bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenomenology, clinical profile, and substance use of patients with unipolar and bipolar depression – A cross-sectional comparative study
Authors: Kathalingam Kanmani Veerappan , Thirumalai Ranganathan
Published: May 2024

Background:

A comparison of the clinical course and symptom profile of unipolar (UP) and bipolar (BP) depression reveals many similarities as well as subtle differences between the two syndromes. Phenomenological and clinical features that would distinguish BP from UP depression can help in appropriate and early treatment. This could, in turn, influence the choice of treatment, clinical course, and outcomes. Misdiagnosing BP depression as a major depressive disorder early may result in manic switch and/or rapid cycling. Most of the published literature in this area is from the Western world. We, therefore, aimed to study phenomenology, clinical factors, and substance use among patients with BP and UP depression. This study would potentially contribute to the existing literature and help in better diagnosis and treatment.

Aim and Objectives:

The aim of this study was to assess the clinical profile and substance use among patients with UP and BP depression and to determine the predictors of bipolarity.

Materials and Methods:

Fifty patients with BP and 50 with UP depression who satisfied the International Classification of Diseases, tenth edition criteria were included in our study. We assessed our participants using the Hamilton Rating Scale for Depression, Brief Psychiatric Rating Scale, Alcohol Use Disorders Identification Test, Fagerstrom Test for Nicotine Dependence, and a self-designed, semi-structured pro forma for obtaining sociodemographic, clinical, and substance use profiles.

Results:

Younger males with a greater number of episodes, earlier onset of illness, greater number of hospitalizations, and higher psychotic symptoms were found in our BP depression group. Logistic regression identified male gender, family history of substance use, history of alcohol dependence, ideas of guilt, forgetfulness, psychomotor agitation, deliberate self-harm, delusion, and hallucinations as predictors of bipolarity (odds ratio = 2.97; 2.25; 9.06; 2.45; 2.43; 16.97; 7.11; 9.33; and 11.46, respectively).

Conclusions:

Young male individuals with a history of substance use, psychotic symptoms, and psychomotor agitation should be carefully evaluated for bipolarity. We need prospective studies with a large sample size to identify early clinical markers of bipolarity.
Neuropsychiatry presentation of acute disseminated encephalomyelitis in a young adult
Authors: Subhas Natasha , Pang Nicholas Tze Ping , Thrichelvam Nathisha
Published: May 2024

Acute disseminated encephalomyelitis (ADEM) is an autoimmune inflammatory demyelinating disease of the central nervous system (CNS) involving the spinal cord and white matter of the brain, usually affecting children and young adults after vaccination or an infection. Neuropsychiatric manifestations are common but are less frequently reported in literature. This case details a young man with no previous comorbidities, who presented with a range of neuropsychiatric manifestations including blank stares, catatonic-like symptoms, selective mutism, irritability, aggression, and visual hallucination. Magnetic resonance imaging showed focal abnormal signal intensity at the splenium of the corpus callosum, notably mildly hypointense on T1W, hyperintense on T2W/FLAIR with restricted diffusion on ADC/DWI. Minimal patchy enhancement was noted postcontrast. Subtle T2/FLAIR hyperintensities were also seen involving the right medial thalamus. He was diagnosed with monophasic ADEM and initiated on intravenous methylprednisolone 1 g daily; however, he developed potential steroid-induced psychosis and was subsequently changed to orodispersible olanzapine and intravenous immunoglobulin (IVIG) 0.4 g/kg/h for 5 days to which he responded satisfactorily. This case report highlights the importance of treating ADEM with steroids and immunoglobulins as it can result in high psychiatric and physical morbidity and mortality if untreated early.
A comparative study of expressed emotions in caregivers of patients with schizophrenia and bipolar affective disorder
Authors: Katta Subhker , Rao Sireesha Srinivas , Boosa Raghuveer Raju , Elukapally Omesh , Molanguri Umashamkar , Bhavana Sai
Published: May 2024

Background:

While expressed emotions (EEs) have been extensively explored in schizophrenia, there is a notable scarcity of literature concerning their study in bipolar affective disorder (BPAD). Few studies have directly compared EEs in these two psychiatric conditions. This research addresses this gap by examining the nuanced dynamics of emotional expression within familial and social contexts in both schizophrenia and BPAD. Hence, this study was done to investigate and compare the EEs in caregivers of patients with schizophrenia and BPAD.

Methodology:

Sociodemographic data were collected in intake pro forma from caregivers of outpatient and inpatients with a diagnosis of schizophrenia and BPAD as per the International Classification of Diseases 10. Primary caregivers of patients who met inclusion criteria were administered the Family Emotional Involvement and Criticism Scale (FEICS). Patients were administered the Positive and Negative Syndrome Scale (PANSS), Young Mania Rating Scale (YMRS), and Hamilton Depression Rating Scale to study psychopathology. Descriptive statistics such as mean, standard deviation (SD), and unpaired t-test were applied for continuous variables. Chi-square for categorical data, Spearman correlation test was used to study the correlation between the psychopathology of patients and EEs among caregivers.

Results:

The mean score of the perceived criticism subscale of FEICS of caregivers of BPAD was found to be 2.22 ± 0.68 SD and the emotional involvement subscale was 1.54 ± 0.58 SD. The mean score of the perceived criticism subscale of schizophrenia caregivers was 1.72 ± 0.73 and the emotional involvement subscale was 1.34 ± 0.471. The EE score across both perceived criticism and emotional involvement subscales was more in BPAD than in schizophrenia (P ≤ 0.001). There was a statistically significant positive correlation between the YMRS score and perceived criticism subscale scores (P ≤ 0.001), and there was also a statistically significant positive correlation between PANSS scores and perceived criticism and emotional involvement subscales of EE (P ≤ 0.001). No association was found between the severity of EE and sociodemographic factors of caregivers.

Conclusions:

The presence of high scores of EE among caregivers of BPAD signifies psychopathology in the family. This calls for providing psychosocial measures for caregivers so that they can take care of their ill family members effectively.
Linguistic equivalence, internal consistency, and factor structure of the Telugu version of the PRIME Screen-Revised, a tool to screen individuals at clinical high risk for psychosis
Authors: Tikka Sai Krishna , Kusneniwar Govindrao N. , Agarwal Neeraj , D’Avossa Giovanni , Katshu Mohammad Zia Ul Haq
Published: May 2024

Background:

Research from India studying individuals at high risk of psychosis is deemed necessary. The Prevention through Risk Identification, Management, and Education (PRIME) Screen-Revised (PS-R) is a commonly used tool to screen individuals at high risk of psychosis. We aimed to translate PS-R into Telugu and assess the linguistic equivalence, reliability (internal consistency), and factor structure of the PS-R, administered in a community youth sample.

Methodology:

PS-R was translated to Telugu by the standard “forward-translation-back-translation” method, and linguistic equivalence was assessed in 20 bilingual youth by Haccoun’s technique. Data for assessing reliability and factor structure were collected using a community-based household study conducted in the Yadadri Bhuvanagiri district of Telangana. Two villages from a rural area, Bommalaramaram, and two wards from an urban area, Bhongir, were chosen. Data from 613 (387 rural and 226 urban) youth aged 15–24 years were included in the analysis. Spearman–Brown coefficient was calculated as a measure of split-half reliability. An exploratory factor analysis was conducted to measure its factor structure.

Results:

Linguistic equivalence was statistically confirmed using inter-version correlation coefficients. Spearman–Brown reliability coefficient was 0.774. Principal component analysis showed that 12 scale items were significantly loaded by 3 latent factors with eigenvalues of 3.105, 1.223, and 1.08, respectively. Factor solution showed that 6, 3, and 2 items correlated with the three factors, respectively.

Conclusions:

We conclude that the Telugu version of the PS-R is fairly reliable and valid for screening individuals at high risk for psychosis among community youth. The three factors represent “positive symptoms of schizophrenia and distress,” “positive schizotypy,” and “apophenia and magical foretelling.”
Neuroleptic Malignant Syndrome with haloperidol in a patient with alcohol withdrawal delirium
Authors: Naik Ajit , Awake Pratik
Published: May 2024

Neuroleptic malignant syndrome (NMS) is a serious side effect of antipsychotic drugs. Alcohol withdrawal delirium and NMS can present with similar symptoms and hence can create confusion. We present a case of a young male who had no underlying medical illness except alcohol use disorder but developed NMS with a single dose of haloperidol (5 mg) in withdrawal delirium state. Alcohol has been reported to cause polymorphism in the D2 dopamine receptors, which is also the site of action for antipsychotic medicines. Apart from this, dehydration, physical exhaustion, and restraint use may have increased the risk of NMS in our patient. We managed both the conditions, alcohol withdrawal delirium and NMS, simultaneously with lorazepam and bromocriptine.
Placental thickness and its relationship to gestational age and fetal growth parameters in normal singleton pregnancies in the central region of Togo
Authors: Gbande Pihou , Tchaou Mazamaesso , Kafupi Pacifique Kwokwo , Sonhaye Lantam , Agoda-Koussema Lama Kegdigoma , Adjenou Komlanvi
Published: May 2024

Introduction:

Accurate determination of gestational age (GA) is necessary for qualitative obstetric care, and ultrasound fetal biometry parameters are used when the last menstrual period is not known. The aim of this study was to measure by ultrasound the placental thickness (PT) and correlate it with GA and fetal growth parameters.

Population and Methods:

This was a descriptive cross-sectional study conducted in the Radiology and Medical Imaging Department of Sokode Regional Hospital. All low-risk pregnancies from the 11thweek were included. Excel and R 4.2.2 software were used. A significance level of 5% was established for the statistical tests.

Results:

A total of 256 pregnancies were recorded. The mean of PT was 29.89 ± 7.42 mm. The mean of PT in the first, second, and third trimesters was 13.50 ± 3.67 mm, 24.61 ± 4.12 mm, and 34.65 ± 4.17 mm, respectively. There was a strong positive linear correlation between PT and GA (r= 0.87,P< 0.00001) and between PT and estimated fetal weight (EFW) (r= 0.80,P< 0.00001). The linear relationship between PT and GA could be expressed by the equation: GA = 0.894*PT-0.103. Similarly, the linear relationship between PT and EFW could be expressed by the equation EFW = 127.314*PT-2563.561. There was a strong linear correlation between PT and parameters such as biparietal diameter (r= 0.88,P< 0.00001), head circumference (r= 0.89,P< 0.00001), and femur length (r= 0.89,P< 0.00001).

Conclusions:

This study demonstrated a correlation between PT and fetal growth parameters, suggesting that PT can be utilized to monitor fetal growth.
Construction of a Multicellular Communication Network Model for Cell Co-Culture Technology and Evaluation of Its Simulation Capability
Authors: Geng Yuan-Yuan , Wei Chao , Chen Guo-Fei , Zhang Bai-Xia
Published: May 2024

Objective:

Cell co-culture technology has been widely used to analyze the effects of drugs on cell proliferation and the expression of some proteins in cells, especially in the field of traditional Chinese medicine (TCM); however, the interactions between cells and the transmission of TCM effects between cells have not been adequately studied.

Materials and Methods:

Using data on gene transcription regulation, biological response, signal channel, and cell-specific expression protein, we built a network for cell types based on entity grammar. Through the correspondence and location information of signal molecules and receptors, type-specific networks of single cells were connected and a multicellular network of smooth muscle cells, neurons, and vascular endothelial cells was constructed. The mechanism of action of nimodipine was analyzed based on the multicellular communication network and its simulation capability was evaluated.

Results:

The outputs generated by the model developed in this study showed that nimodipine inhibited smooth muscle contraction, due to the overload of Ca2+ and the toxicity of excitatory amino acids, and protected neurons and vascular endothelial cells by supporting cell proliferation and inhibiting cell apoptosis. These results were consistent with the known mechanism of nimodipine action, thus confirming that the multicellular network can be used to study the transmission of drug effects among cells.

Conclusions:

This study lays a foundation for the analysis of the transmission of drug effects in multi-cells, tissues, organs, and other spatial scales through multicellular co-culture experiments, based on a multicellular communication network. In addition, it provides a biological network model for the analysis of TCM action mechanisms.
Inhibiting Effect and Mechanism of Aconitum tanguticum (Maxim.) Stapf on Intestinal Fibrosis of CCD-18Co Cells
Authors: Cui Qin-Dan , Shen Li-Dan , Bai Yuan , Azhar Muhammad , Deng Jun , Huang Xian-Ju , Tong Hai-Ying
Published: May 2024

Objective:

The objective of the study was to explore the potential signaling mechanism of Aconitum tanguticum (Maxim.) Stapf (ATS) and its impact on intestinal fibrosis in vitro.

Methods:

Network pharmacology was used to screen the active components of ATS and predict their potential targets in intestinal fibrosis. The protein–protein interaction network graph was constructed using drug–disease intersection targets retrieved from the Search Tool for Retrieval of Interacting Genes/Proteins database. The network diagram was analyzed using Cytoscape 3.6.1’stopology function. The gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were conducted using the database for annotation, visualization, and integrated discovery platform. Intestinal fibroblast model in vitro was constructed using transforming growth factor-β1 (TGF-β1)-induced CCD-18Co cells. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used to verify the network pharmacology-predicted antifibrotic signaling pathway of ATS and the traditional antifibrotic signaling pathway.

Results:

Network pharmacology revealed that there were 19 active components in ATS, suggesting that ATS could be involved in the regulation of mitogen-activated protein kinase 1 (MAPK1), PIK3CA, MAPK3, and other important targets that are present in cancer pathways, including proteoglycans, influenza A, and phosphatidylinositol-3-kinase (PI3K)-protein kinase B (Akt) signaling pathways. The results of quantitative reverse transcription-polymerase chain reaction (qRT-PCR) demonstrated that 0.1–1 μg/mL ATS may suppress tissue inhibitor of metalloproteinase 1, collagen I, and alpha-smooth muscle actin expression levels. The expression of the TGF-β/suppressor of the mother against decapentaplegic (Smad) and PI3K/Akt signaling pathways was controlled by ATS. In addition, ATS inhibited the PI3K/Akt pathway by reducing the expression of MAPK1, HSP90AA1, and PIK3CA.

Conclusions:

It has been confirmed that ATS is a multipathway and multitarget treatment for intestinal fibrosis. This study suggested that ATS might alleviate intestinal fibrosis by blocking both the TGF-β/Smad and the PI3K/Akt pathway.
RoCK blocks for affine categorical representations
Authors: Webster Ben
Published: May 2024

Given a categorical action of a Lie algebra, a celebrated theorem of Chuang and Rouquier proves that the blocks corresponding to weight spaces in the same orbit of the Weyl group are derived equivalent, proving an even more celebrated conjecture of Broué for the case of the symmetric group. In many cases, these derived equivalences are

t

-exact and thus induce equivalences of abelian categories between different blocks. We call two such blocks “Scopes equivalent.” In this paper, we describe how Scopes equivalence classes for any affine categorification can be classified by the chambers of a finite hyperplane arrangement, which can be found through simple Lie theoretic calculations. We pay special attention to the largest equivalence classes, which we call RoCK, and show how this matches with recent work of Lyle on Rouquier blocks for Ariki–Koike algebras. We also provide Sage code that tests whether blocks are RoCK and finds RoCK blocks for Ariki–Koike algebras.
Fecal microbiota transplantation in the treatment of hepatic encephalopathy: A perspective
Authors: Samanta Arghya , Sen Sarma Moinak
Published: May 2024

Due to its complex pathogenesis, treatment of hepatic encephalopathy (HE) continues to be a therapeutic challenge. Of late, gut microbiome has garnered much attention for its role in the pathogenesis of various gastrointestinal and liver diseases and its potential therapeutic use. New evidence suggests that gut microbiota plays a significant role in cerebral homeostasis. Alteration in the gut microbiota has been documented in patients with HE in a number of clinical and experimental studies. Research on gut dysbiosis in patients with HE has opened newer therapeutic avenues in the form of probiotics, prebiotics and the latest fecal microbiota transplantation (FMT). Recent studies have shown that FMT is safe and could be effective in improving outcomes in advanced liver disease patients presenting with HE. However, questions over the appropriate dose, duration and route of administration for best treatment outcome remains unsettled.
Presepsin as a biomarker of bacterial translocation and an indicator for the prescription of probiotics in cirrhosis
Authors: Efremova Irina , Maslennikov Roman , Poluektova Elena , Medvedev Oleg , Kudryavtseva Anna , Krasnov George , Fedorova Maria , Romanikhin Filipp , Zharkova Maria , Zolnikova Oxana , Bagieva Gyunay , Ivashkin Vladimir
Published: May 2024

BACKGROUND

The gut–liver axis and bacterial translocation are important in cirrhosis, but there is no available universal biomarker of cellular bacterial translocation, for which presepsin may be a candidate.

AIM

To evaluate the relationship of the blood presepsin levels with the state of the gut microbiota in cirrhosis in the absence of obvious infection.

METHODS

This study included 48 patients with Child–Pugh cirrhosis classes B and C and 15 healthy controls. The fecal microbiome was assessed using 16S rRNA gene sequencing. Plasma levels of presepsin were measured. A total of 22 patients received a probiotic (Saccharomyces boulardii ) for 3 months.

RESULTS

Presepsin levels were higher in patients with cirrhosis than in healthy individuals [342 (91-2875) vs 120 (102-141) pg/mL; P = 0.048]. Patients with elevated presepsin levels accounted for 56.3% of all included patients. They had lower levels of serum albumin and higher levels of serum total bilirubin and overall severity of cirrhosis as assessed using the Child–Pugh scale. Patients with elevated presepsin levels had an increased abundance of the main taxa responsible for bacterial translocation, namely Bacilli and Proteobacteria (including the main class Gammaproteobacteria and the minor taxa Xanthobacteraceae and Stenotrophomonas), and a low abundance of bacteria from the family Lachnospiraceae (including the minor genus Fusicatenibacter), which produce short-chain fatty acids that have a positive effect on intestinal barrier function. The presepsin level directly correlated with the relative abundance of Bacilli, Proteobacteria, and inversely correlated with the abundance of Lachnospiraceae and Propionibacteriaceae. After 3 months of taking the probiotic, the severity of cirrhosis on the Child–Pugh scale decreased significantly only in the group with elevated presepsin levels [from 9 (8-11) to 7 (6-9); P = 0.004], while there were no significant changes in the group with normal presepsin levels [from 8 (7-8) to 7 (6-8); P = 0.123]. A high level of presepsin before the prescription of the probiotic was an independent predictor of a greater decrease in Child–Pugh scores (P = 0.046), as well as a higher level of the Child–Pugh scale (P = 0.042), but not the C-reactive protein level (P = 0.679) according to multivariate linear regression analysis.

CONCLUSION

The level of presepsin directly correlates with the abundance in the gut microbiota of the main taxa that are substrates of bacterial translocation in cirrhosis. This biomarker, in the absence of obvious infection, seems important for assessing the state of the gut–liver axis in cirrhosis and deciding on therapy targeted at the gut microbiota in this disease.
Mid-8th Century CE Seismic Sequences Along the Dead Sea Transform
Authors: Williams Jefferson
Published: May 2024

A comprehensive examination of textual, archaeoseismic, paleoseismic, tsunamogenic, and paleo-landslide evidence was used A comprehensive examination of textual, archaeoseismic, paleoseismic, tsunamogenic, and paleo-landslide evidence was used to characterize and construct a timeline for a series of earthquakeswhich struck the vicinity of the Dead Sea Transform in the middle of the 8th century CE. Particular attention was paid to nearly coincidental dates reported in Byzantine, Coptic and Judaic sources along with the time of day reported in three different textual accounts: Pseudo-Dionysius of Tell-Mahre, an apparently local and contemporaneous source, along with Severus Ibn al-Muqaffa’ and Mujir al‑Din both of whom sourced earlier accounts which were written in the first person and purport to reproduce eye-witness testimony. The timeline, supported by archaeoseismic evidence in Bet She’an and Pella, suggests that the Sabbatical Year Earthquakes likely struck within 17 hours of each other, the first one at night and the next one the following morning, between the Julian calendar dates of 16 and 19 January in 749 CE rather than being separated by 3 years. Insight from historical scholarship was used in conjunction with other observations to propose reasons why the disparate earthquake accounts present seemingly incompatible reports of earthquake timing. While the conclusions of this article provide a hypothetical rather than a definitive solution to the Sabbatical Year Earthquakes conundrum, it does appear that some sort of seismic unzipping1 occurred within a short amount of time and a number of destructive earthquakes, perhaps as many as six, impacted the Dead Sea Transform in the middle of the 8th century CE leading to widespread devastation from South to North and points in between.
Scintillation Climatology from a Software Defined Radio Receiver over Antarctica
Authors: Imam Rayan , Alfonsi Lucilla , Spogli Luca , Cesaroni Claudio , Ebrahimi Mehr Iman , Minetto Alex , Dovis Fabio
Published: May 2024

Software-Defined Radio (SDR) Global Navigation Satellite System (GNSS) receivers for operational Ionospheric Scintillation Monitoring (ISM) have faced challenges and were deemed failures by many research projects. The need for a highly stable oscillator and a robust real-time signal-tracking capability have been the main challenges. The Istituto Nazionale di Geofisica e Vulcanologia (INGV) led a project called DemoGRAPE (Demonstrator of GNSS Research and Application for Polar Environment) to deploy an SDR GNSS Receiver in SANAE IV Antarctica station, which has been continuously operating since January 2016. The SDR receiver was designed by the Navigation Signal Analysis and Simulation (NavSAS) group in collaboration with the Joint Research Centre (JRC) of the European Commission.  The system deploys the SDR in parallel to a Septentrio PolaRxS ISM receiver. The two receivers are fed by the same receiving antenna (i.e., they share the same field of view and, hence, cross the same portion of the ionosphere) such that they receive quasi-identical signals except for the independent effects of their front-ends. The SDR produces as output a log file, equivalent to the ISM record produced by PolaRxS, that contains the amplitude and phase scintillation indexes. In addition to this, the SDR system records the raw digital samples of the GNSS signal when the internal algorithm of the receiver detects scintillation presence. These data can be used to replicate the scintillation event in the laboratory and perform dedicated post-processing of the raw signal itself. The system has been in operation for over seven years now, spanning more than half a solar cycle. It has recorded several geomagnetic storm events as well as abundant data in quiet conditions. To the best of our knowledge, this is the longest dataset of this nature (co-located PolaRxS and SDR  receivers). We compare the performance of the two receivers by analyzing the scintillation climatology maps obtainable from both receivers' data. Here, the climatology is obtained using the well-established Ground Based Scintillation Climatology (GBSC) technique from the data provided by the two different receivers.  The study shows that the SDR climatology maps under disturbed geomagnetic conditions are equivalent to those obtained from the PolaRxS receiver. Under quiet conditions, the SDR shows more scintillation events than the PolaRxS. Carefully inspecting the differences in the scintillation occurrence between the two receivers, they seem not to happen randomly but mainly concentrated along the expected (climatological) position of the auroral oval. This means that the SDR application for space weather monitoring could be possible and that the SDR could be utilizable as an informative tool by the ionospheric scintillation community.
Remote sensing, archaeology and historical records: looking for 1624 earthquake traces in San Giorgio parish church of Argenta (Italy)
Authors: Pesci Arianna , Fabiana Loddo Fabiana Loddo , Giordano Teza Giordano Teza , Alessandra Rossetti Alessandra Rossetti
Published: May 2024

The present work is part of a research program financed by INGV in order to look for traces of earthquakes occurred in the past on historical buildings. At that aim, a method based on remote sensing techniques was proposed and applied to San Giorgio parish church in Argenta (Ferrara, Italy). That church was chosen because of notable availability of historical and archaeological material, already catalogued in the past years, allowing the identification of structures belonging to periods before and after the 1624 earthquake. Data provided by terrestrial remote sensing techniques (digital photogrammetry supported by laser scanning) made possible the recognition of patterns that could be due to that strong seismic event or, in general, to one or more calamitous events. The results show that the proposed method can provide potentially useful data to help confirming or excluding historical hypotheses or helping to fill information gaps. However, it should be stressed that the proposed approach does not enable the identification of unknown seismic events, providing instead data that can be associated with already known events.
Gece Eğlencelerinde Yeni Bir Deneyim: Girls Night Out
Authors: Tural Goncagül
Published: May 2024

Eğlence anlayışı yıllar boyunca bireylerin ilgi ve ihtiyaçları doğrultusunda gelişmiş ve yeni şekiller almıştır. Kentli insanın eğlence ihtiyacını karşılamak amacıyla kentlerde çeşitli eğlence mekânları açılmıştır. Barlar ve gece kulüpleri kent merkezlerinde açılan eğlence mekânlarındandır. Gece hayatı bakımından dinamik olan Eskişehir, barındırdığı bar ve gece kulüpleriyle her kesimden ve yaş grubundan bireye zengin bir eğlence hizmeti sunmaktadır. Öğrenci şehri olarak da anılan şehirde özellikle öğrencilerin eğlence anlayışlarına yönelik düzenlenen çeşitli konsept partilerle genç kesimin eğlence ihtiyacı karşılanmaya çalışılmaktadır. Düzenlenen partilerden biri de çalışmanın konusunu oluşturan “Girls Night Out” partisidir. Türkiye’de ilk kez, sadece kadınlara özel olarak bir gece kulübünde düzenlenen bu parti ile kadınlara hemcinsleriyle eğlenebilecekleri bir gece kulübü ortamı sunulmuştur. Yazıda, sadece kadınların katılabildiği Girls Night Out adlı parti, yapısal ve işlevsel yönleriyle ele alınmıştır. Çalışmanın verileri gözlem ve derinlemesine mülakat yöntemleri kullanılarak elde edilmiştir. Yapılan değerlendirmeler sonucunda, kadınlara özel düzenlenen partide, kadınların karma bir gece kulübünde olduğundan daha özgür ve güvende hissettikleri, gündelik hayatta tercih etmedikleri kıyafetleri giydikleri ve oluşan bu güvenli ortamın alkol tüketim biçimlerine de yansıdığı görülmüştür.
Intracranial Hypotension Induced by Cervical Chiropraxis
Authors: Kim El
Published: May 2024

Chiropractic care, known for its non-invasive and hands-on approach to healthcare, can occasionally lead to adverse reactions. This case report details an unusual occurrence of intracranial hypotension (IH) in a 30-year-old female who received chiropractic care for neck pain. The patient experienced a throbbing positional headache five days after mobilization and adjustment of the cervical spine. Upon admission, lumbar puncture performed in the lateral position revealed an opening pressure of 55 mm H2O. Magnetic resonance imaging showed subdural fluid collection and diffuse pachymeningeal enhancement in the cerebral hemispheres. Radioisotope cisternography revealed dural leakage at the upper cervical level. Following unsuccessful supportive measures, the patient underwent treatment with an epidural blood patch. After the treatment, her postural headaches completely subsided without recurrence. This report underscores that IH syndrome is a rare yet clinically significant complication that may be associated with manipulation of the upper spine.
Remote Teleassessment and Telerehabilitation of a Comprehensive Exercise Training Protocol for Older Adults: Design and Methodology of a Usability Protocol
Authors: Subramaniam Savitha , Kitsiou Spyros , Bhatt Tanvi
Published: May 2024

Purpose: The design, usability, safety, and feasibility of a telehealth protocol comprising teleassessment and tele rehabilitation to evaluate and improve physical and cognitive function among older adults was assessed. Methods: Healthy older adults (n=23) participated in a pre-post tele-assessment of a 4-week (3 sessions/week) telerehabilitation session. Tele-assessment was performed to evaluate balance, gait function, and cognition. Tele-rehabilitation sessions comprised of balance games, dancing, dual-tasking, yoga, and tai-chi exercises. Results: There were no adverse events reported to indicate concerns with the safety of the current telehealth protocol. Conclusion: The proposed telehealth protocol to assess and improve physical and cognitive function may be feasible for enrolling older adults into a home exercise trial.
Analisis Pengaruh Gender dalam Pemilihan Jurusan Pariwisata di Universitas di Kota Bandung
Authors: Gunawan Putri Keysya , Febriyanto Azfa Bayu , Trisnadiwan Raisya Nazwa Ayudia , Salsabila Raihan Zulfa , Adhisty Dhestrianita , Sugiarto Firdaus Rizqullah , Rozak Rama Wijaya Abdul
Published: May 2024

Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang mempengaruhi pemilihan jurusan pariwisata berdasarkan gender di universitas di Kota Bandung. Penelitian ini menggunakan pendekatan kuantitatif dengan desain penelitian survei menggunakan skala Likert. Hasil penelitian menunjukkan bahwa faktor gender, persepsi prospek karier, kekhawatiran terhadap diskriminasi gender dan pelecehan seksual, serta pertimbangan rasio gender, mempengaruhi pemilihan jurusan pariwisata. Temuan ini menegaskan pentingnya upaya untuk mengatasi stereotip gender dan diskriminasi dalam industri pariwisata.
Analysis of actual nutrition of schoolchildren at different age periods
Authors: Tapeshkina Natalia V. , Logunova Tatyana D. , Korsakova Tatyana G. , Pestereva Dina V.
Published: May 2024

Introduction. A healthy, balanced diet can provide the child with nutritional protection from adverse environmental factors and helps to prevent diseases. Lack
of continuity in nutrition at school and at home creates a deficit in the diet supply of nutrients necessary for a growing body.
The purpose of the investigation is to study the actual nutrition of a group of schoolchildren at different age periods (in the dynamics of 10 years).
Materials and methods. Actual nutrition of a group of schoolchildren in the dynamics over 2009 and 2019. The sample consisted of one hundred fifty 7-years children and the same children aged 17 years (124 children). Actual nutrition was studied using menu-layouts (at school) and the method of 24-hour (daily) nutrition reproduction (at home).
Results. With age, there is a more pronounced imbalance in the supply of basic nutrients in the diet, associated with excess consumption of fats (7–25%), lack of carbohydrates, deficiency of dietary fibers (15–20%), a number of minerals (calcium, magnesium, iron) and vitamins (C, B1, B2, A, PP). Average daily food rations are unbalanced. The structure of children’s food sets becomes more irrational with increasing age. Regardless of the period of the study, diets are deficient in the level of consumption of milk, fish, vegetables, and fruits, and excessive in the level of consumption of foods with high energy value. In dynamics, the percentage of children with the recommended level of consumption of poultry is decreasing by 4.3 times, fish – by 3.8 times, milk – by 3 times, fermented milk products –
by 2.6 times, cottage cheese and sour cream – by 2 times, butter and vegetable – 15.4 and 6.8 times, respectively.
Limitations. This study is limited to a sample of a group of schoolchildren studying from the 1st to the 11th grade (in the dynamics with a ten-year interval).
Conclusion. Persistent long-term violations of the basics of a healthy balanced diet by children create a probable risk of developing diseases in children in the future caused by nutritional factors, and can also be predictors of the development of pathological conditions and diseases in adulthood.
Trend in indices of public health risk caused by air pollution in an industrial center
Authors: Kislitsyna Vera V. , Surzhikov Dmitry V. , Likontseva Yuliya S. , Shtaiger Varvara A.
Published: May 2024

Introduction. In industrialized regions and cities, atmospheric air pollution greatly contributes to the hazard for public health.
The study aim was to assess the state of the atmospheric air in the city of Novokuznetsk over 2017–2022 and determine the levels of risks to public health.
Materials and methods. Data on gross atmospheric emissions and average annual concentrations of the substances was taken from the reports on the state of the environment of the Kemerovo region and Novokuznetsk. Maximum permissible concentrations of atmospheric pollutants were determined according to SanPiN 1.2.3685–21. Calculations of the risks to public health were carried out in accordance with Guideline P 2.1.10.1920–04. The classification of risk levels was carried out on the basis of MR 2.1.10.0156–19. 2.1.10.
Results. Decrease in total atmospheric emissions from 2017 to 2022 amounted to 50.1 thousand tons (about 16%). At the same time, there was revealed an excess of the average annual maximum permissible concentrations of benzo(a)pyrene (3.5-11.2 times); formaldehyde (1.7 and 3.4 times over 2021 and 2022, respectively); suspended substances (1.6 and 2.0 times in 2021 and 2022, respectively); hydrogen fluoride (1.2 times in 2021); nitrogen dioxide (1.6 times in 2022). The hazard coefficients of benzo(a)pyrene were 3.5–11.2 (high level of non-carcinogenic risk); formaldehyde and suspended substances – 1.1–3.0 (alarming level).
In 2022, the hazard coefficient for formaldehyde was 3.4 (high risk level), suspended substances – 2.0, nitrogen dioxide – 1.6 (alarming risk level). Hazard indices of pollutants were detected in the range from 7.0 to 20.1 (high level of risk). The main critical organs and systems were the immune system (hazard indices were 4.0–14.6), development during childhood (hazard indices – 3.5–11.2), respiratory organs (hazard indices – 3.0–8.6). These risk levels range from alarming to high. The highest total individual carcinogenic risk (1.6•10–4) was determined in 2021 (alarming level), the main contribution is made by formaldehyde.
Limitations. In 2022, there were no data on carbon (soot) concentrations, so the level of total carcinogenic risk this year cannot be considered to be correct.
Conclusion. Reducing the total volume of atmospheric emissions does not provide a significant effect on improving the environmental situation and public health, since high concentrations of pollutants remain in the city’s atmosphere. When implementing air protection measures, it is necessary to take into account risk criteria.
Impact of COVID-19 on the Supply Chain of the Food Industry: A Literary Analysis
Authors: Nwagwu Urenna
Published: May 2024

The devastating impact of COVID-19 on different business functions cannot be undermined. This effect was highly disruptive for the food industry where a number of businesses closed down whilst a significant number of businesses had gone bankrupted. Considering this stance, this study explored the impact of COVID--19 on the supply chain of the food industry which was also the objective of this study. The research opted for interpretivism paradigm and qualitative research approach, following which literary analysis of the previous studies conducted within this domain was compared and analyzed. Findings of the study identified that COVID-19 directly hindered the food industry's supply chain in the times of seasonal employment where most of the migrant workers were unavailable due to sickness, lockdown restrictions, or any sort of travel restrictions. Besides that, streamlining and managing the flow of food ensuring that all the stages of the supply chain in the food industry are completed effectively was identified as another key challenge. Likewise, economic shrinkage and reallocation of resources paralyzed the economy of many countries and, hence, hindered governmental institutions' capacity to provide financial incentives to the companies. In addition, logistical efficiency was also affected due to prolonged lockdown, devastating the fine-tuned schedule and causing disruption in the food supply chain. Therefore, many foodproducing companies either closed their operations or had to reduce their production or operational capacity, which further resulted in increased demand, less supply, and less sales or profitability of the food businesses. it is recommended for the food businesses to consider restructuring their business models specifically related to progressive investment in the domain of supply chain. Companies need to foster collaboration among different actors or stakeholders of supply chain including an integration of raw material supply, manufacturing of food products and a streamlined chain of their supply in the market.
A Survey of Simultaneous Localization and Mapping with an Envision in 6G Wireless Networks
Authors: Huang Baichuan , Zhao Jun , Luo Sheng , Liu Jingbin
Published: May 2024

Simultaneous Localization and Mapping (SLAM) achieves the purpose of simultaneous positioning and map construction based on self-perception. The paper makes an overview in SLAM including Lidar SLAM, visual SLAM, and their fusion. For Lidar or visual SLAM, the survey illustrates the basic type and product of sensors, open source system in sort and history, deep learning embedded, the challenge and future. Additionally, visual inertial odometry is supplemented. For Lidar and visual fused SLAM, the paper highlights the multi-sensors calibration, the fusion in hardware, data, task layer. The open question and forward thinking end the paper. The contributions of this paper can be summarized as follows: the paper provides a high quality and full-scale overview in SLAM. It's very friendly for new researchers to hold the development of SLAM and learn it very obviously. Also, the paper can be considered as dictionary for experienced researchers to search and find new interested orientation.
A Geometry-based Ambiguity Validation (GBAV) Method for GNSS carrier phase observation
Authors: Chen Wu , Xu Ying , Weng Duojie , Ji Shengyue
Published: May 2024

Integer ambiguity validation is an indispensable and critical step in GNSS carrier phase positioning for precise and reliable positioning applications. The crucial problems associated with any ambiguity validation methods are as follows. 1) The fixed ambiguity vector can be separated from all other ambiguity candidates under certain tests (separability). 2) The probability of fixing to wrong ambiguity combinations (mis-fixing) can be controlled to an acceptable level based on different application requirements. Traditional ambiguity validation methods, such as the R-ratio and the difference tests which use one statistical test to control both separability and mis-fixing rate, are widely used due to easier computation. The performances of these methods are generally acceptable. However, experiments show that these tests with a fixed threshold can cause either a small percentage of mis-fixing or overly conservative with long observation time. In this paper, we propose a new Geometry Based Ambiguity Validation (GBAV) method which uses two statistical tests to control geometry separability and mis-fixing probability separately. The thresholds for both tests can be strictly determined based on user requirements to control the quality of ambiguity resolution. Three 24-hour GNSS (GPS, BDS) datasets (two short baselines and one middle-range baseline) are processed using the proposed GBAV method, and compared with the popular R-ratio method. The results show that by giving proper control on the mis-fixing probability (0.01%), there is no mis-fixing case in all three datasets.
Analisis Kemampuan Berpikir Kritis dan Berpikir Logis Siswa dalam Memecahkan Masalah Matematis Berbasis Etnomatematika Kain Tenun Tembe Nggoli Bima
Authors: Wahyuni Sry , Kusaeri Al
Published: May 2024

Kemampuan berpikir kritis dan berpikir logis merupakan kemampuan yang diperlukan di abad 21 dimana arus informasi sangat dinamis. Informasi dapat diperoleh dari manapun dan kapanpun dari berbagai sumber yang belum tentu dapat dipertanggungjawabkan kebenarannya.. Penelitian ini bertujuan untuk mendeskripsikan kemampuan berpikir kritis dan berpikir logis siswa dalam memecahkan matematis berbasis etnomatematika kain tenun tembe nggoli Bima. Penelitian deskriptif ini menggunakan pendekatan kualitatif dengan melibatkan 3 subjek yaitu tinggi, sedang dan rendah. Instrumen penelitian ini sebanyak 3 soal yang telah memenuhi kriteria validasi dan reabilitas. Selain itu, pedoman wawancara digunakan untuk menguatkan hasil penelitian. Temuan yang diperoleh adalah siswa yang mempunyai kemampuan tinggi memenuhi 4 indikator KBK dan 3 indikator KBL, kemampuan sedang memenuhi 3 indikator KBK dan 2 indikator KBL dan kemampuan rendah memenuhi 2 indikator KBK dan 1 indikator KBL.
الهدنات البحرية وأثرها على مشيخات الساحل المتصالح العربية في القرن التاسع عشر الميلادي
Authors: Alkhalifa Abdulla Bin Ali
Published: May 2024

لقد تمكنت بريطانيا من إبرام معاهدات الهدنات البحرية مع مشيخات الخليج المتصالح على فترات متتالية من القرن التاسع عشر الميلادي والتي كان مردودها يصب في مصلحة مياه الخليج العربي في الوقت الذي كانت فيه البحرية البريطانية غير كافية لتغطية مياه الخليج العربي من أجل فرض السلم والأمن البحري دون التوغل في البر، وذلك ما كان يهم السياسة البريطانية من أجل مرور وعبور سفنها العسكرية والتجارية من جنوب الخليج العربي إلى شماله بسلام ودون أية عراقيل أمنية. تعتبر الهدنات البحرية ما بين بريطانيا ومشيخات الساحل المتصالح من أهم الروابط السياسية التي تمكنت من خلالها بريطانيا من فرض سيطرتها ونفوذها على الخليج العربي، والتي بدورها انعكست على السلم البحري من بعد تنفيذ أول المعاهدات التي تمكنت من خلالها لندن من ربط المشيخات الخليجية بها سياسياً وأمنياً واقتصادياً منذ مطلع عام 1820م، كما أن معاهدات الهدنات البحرية استخدمت من قبل بريطانيا كأداة قانونية وسياسية ربطت من خلالها بريطانيا المشيخات الخليجية بصيغ قانونية وسياسية ملزمة، تتجلى أهمية البحث في تسليط الضوء على فترة الهدنات البحرية التي أتت كنوع من الضوابط الأمنية البحرية، وكذلك التعرف على موقف المشيخات العربية منها. يسعى البحث في معرفة الآثار السلبية على أفراد القبائل العربية جراء اضطراب الحالة الأمنية والسياسية المفروضة من قبل بريطانيا، إذ فرضت بريطانيا سيطرتها على مياه الخليج العربي، لمصلحتها في الحفاظ على سلامة أساطيلها وتجارتها العالمية، وغفلت عن مردود السلبيات على المشيخات العربية. لقد حُددت الإجابة على إشكالية البحث على الأسباب التي أدّت إلى الهدنات البحرية وعلى ماذا تنص عليه. في حين بُني البحث على فرضية أن تلك الهدنات قد أحدثت تغييراً في مستوى الأمن، وكذلك قد أنهت التعديات البحرية في مياه الخليج العربي. لقد أستلزم البحث الاعتماد على المنهج التاريخي لتتبع الأحداث، والمنهج الوصفي التحليلي الذي يقوم على النقد والتحليل. وخلص البحث إلى أن الهدن البحرية قادت إلى حصول بريطانيا على صلاحيات واسعة، وبموجب ذلك أصبحت مياه الخليج العربي بحيرة بريطانية مغلقة.
Predicting Student Achievement via Machine Learning: Evidence from Turkish Subset of PISA
Authors: Erdoğan Selin , Taştan Hüseyin
Published: May 2024

This study seeks to identify the determinants of academic performance in mathematics, science, and reading among Turkish secondary school students. Using data from the OECD's PISA 2018 survey, which includes several student- and school-level variables as well as test scores, we employed a range of supervised machine learning methods specifically ensemble decision trees to assess their predictive performance. Our results indicate that the boosted regression tree (BRT) method outperforms other methods bagging and random forest regression trees. Notably, the BRT highlights the importance of general secondary education programs over vocational and technical (VAT) education in predicting academic achievement. Moreover, both characteristics specific to student and school environment are demonstrated to be significant predictors of academic performance in all subject areas. These findings contribute to the development of evidence-based educational policies in Turkey.