bluuebunny/crossref_metadata_2025 huggingface dataset:
Telomere fragility in radiology workers occupationally exposed to low doses of ionising radiation
Authors: Tričković Jelena Filipović , Šobot Ana Valenta , Joksić Ivana , Joksić Gordana
Published: April 2022

Ionising radiation damages DNA directly and indirectly through increased production of reactive oxygen species. Although telomeres have been reported as indicators of radiosensitivity, their maintenance in response to occupational exposure to low radiation doses is still a matter of debate. In this work we aimed to investigate telomere length and structure in hospital workers occupationally exposed to X-rays and to relate these findings to oxidation of biomolecules and chromosome aberrations. Blood samples of exposed participants and matching controls were taken during periodical check-ups. Chromosome aberrations and telomere length and structure were analysed in peripheral blood lymphocytes using Q-FISH, whereas oxidative stress parameters [pro/antioxidant balance (PAB), lipid peroxidation, and 8-oxo-dG] were measured in plasma samples. Based on the CA findings we divided the exposed group into two subgroups, of which one had chromosome aberrations in the first division metaphases and the other did not. There was no significant difference in telomere length between any of the groups. However, both subgroups showed significantly higher rate of fragile telomeres and higher lipid peroxidation product and 8-oxo-dG levels than controls. The rate of fragile telomeres significantly correlated with plasma levels of 8-oxo-dG, which suggests that continuous exposure to low radiation doses induces oxidative base damage of guanine resulting in telomere fragility.
Influence of number of visitors and weather conditions on airborne particulate matter mass concentrations at the Plitvice Lakes National Park, Croatia during summer and autumn
Authors: Klaić Zvjezdana Bencetić , Leiva-Guzmán Manuel Andres , Brozinčević Andrijana
Published: April 2022

We investigated the influence of local meteorological conditions and number of visitors on ambient particulate matter (PM) mass concentrations and particle fraction ratios at the Plitvice Lakes National Park between July and October 2018. Outdoor mass concentrations of particles with aerodynamic diameters of less than 1, 2.5, and 10 μm (PM1, PM2.5, and PM10, respectively) and indoor PM1 were measured with two light-scattering laser photometers set up near the largest and most visited Kozjak Lake. Our findings suggest that the particles mainly originated from background sources, although some came from local anthropogenic activities. More specifically, increases in both indoor and outdoor mass concentrations coincided with the increase in the number of visitors. Indoor PM1 concentrations also increased with increase in outdoor air temperature, while outdoor PMs exhibited U-shaped dependence (i.e., concentrations increased only at higher outdoor air temperatures). This behaviour and the decrease in the PM1/PM2.5 ratio with higher temperatures suggests that the production and growth of particles is influenced by photochemical reactions. The obtained spectra also pointed to a daily but not to weekly periodicity of PM levels.
Desplazamiento interno forzado en la sierra de Guerrero, México
Authors: Torres-Oregón Fredyd , Estrada-Rodríguez José Luis
Published: April 2022

Objetivo: discutir el papel de los grupos delictivos en el tejido social de la localidad de estudio y las implicaciones sociales del desplazamiento interno forzado. Metodología: la metodología empleada combina la autoetnografía y la antropología clásica. Resultados: estos muestran que los grupos delictivos condicionan el comportamiento social en la búsqueda de afianzar su poder social y económico. Limitaciones: el trabajo ahonda únicamente en una localidad de la sierra de Guerrero, aspecto que limita extrapolar los resultados para entender el fenómeno del desplazamiento forzado en su total magnitud. Conclusiones: se concluye que los grupos delictivos y su presencia territorial no se ajusta únicamente al control y trasiego de drogas sino intervenir en distintas actividades económicas ante la nula presencia del Estado.
ROB-E – Swarm Robotics for Education in Circular Economy
Authors: Schranz Melanie , Amann Paul , Egger Raphaela , Schifrer Sabrina
Published: April 2022

These days, climate change, robotics and artificial intelligence are discussed on the same level of interest. Our mission is bringing these topics into education: The paper presents the project ROB-E, which aims to pass social and technical skills to pupils of different age groups and school levels (primary and secondary school) in the research fields bionic, robotics, and swarm intelligence encompassing the application of circular economy and environmental protection. This leads to a workshop series that build on one another: After getting into circular-economy-related topics (incl. resource-friendly production, re-use and recycling), pupils design their own robots based on the circular design approach and bionic. They 3D print them with recycled PLA, assemble the individual (electronic) parts and program their robots as a swarm of cleaning robots to collect and sort garbage. Thus, they start an exciting journey with current cutting-edge topics applied on everyday life-situations of pupils.
MATLAB educational tool for teaching Rayleigh random variable
Authors: Jovanovic Dolecek Gordana
Published: April 2022

This paper presents the set of MATLAB demonstrations dedicated to teaching characteristics of Rayleigh random variable, which is important in wireless communication systems, radars, data science, and vibrations, among others. This educational tool is created as a complementary teaching tool in the online classes, during the COVID-19 pandemic, with the aim to help students to better understand the behavior and characteristics of this random variable. The Demo tool consists of three sets of demonstrations:  Description, Parameters and Relation with Other Random Variables, Operations on Rayleigh Random Variable, and Generalization. The demo is made in MATLAB and utilizes all benefits provided by MATLAB, such as simplicity, good graphic environment, and interactive use, among others. Additionally, this demo is used with other demo programs, also made in MATLAB, in teaching/learning process of random variables. Students were very satisfied with this demo tool expressing that helped them understanding better the behavior, and characteristics of the Rayleigh random variable.
Synkretyczne pouczenie jogiczne w Ćarakasanhicie (Śarirasthana 1.137–155)
Authors: Budziszewska Nina
Published: April 2022

A syncretic yogic instruction in Carakasanhita (Śārīrasthāna 1.137–155): Śārīrasthāna (ŚS) 1.137–155, contained in Book 4 of the Ćarakasaṃhitā (1st century BCE — 2nd century CE), is a short treatise on yoga presented for āyurvedic purposes. In its yogic interpretation, the work comprises the Upaniṣads, the Mahābhārata, some Sāṃkhya’s and Vaiśeṣika’s notions as well as the meditative interpretation present in the Buddhist tradition. The ŚS gives a threefold path (ayana) leading to mokṣa (ŚS 150–151), the state of supreme brahman with which the conscious being, bhūtātman, becomes one (ŚS 155): yoga, smṛti, and sāṃkhya. The path to liberation is based on yoga, which is the reinforcement of the manas in the ātman (ŚS 138) and the stopping of suffering by breaking the connection between the erroneous identification of ātman with manas and the senses (ŚS 138–139). On the path of yoga, a powerful eight-fold magical power (eight siddhis) is created through which the yogi is able to overcome external adversities (ŚS 140–141). In the next step, the recognition of the one’s true identity — according to the sāṃkhya — is made through buddhi by the power of jñāna (ŚS 152–153). However, in order for this recognition to be realized, the state of purity of sattva (ŚS 141) must first appear, induced by the practice of the eight-step smṛti realized by eighteen perfections (ŚS 143–147).
Dziewczyńska bajka? O Córce Czarownic Doroty Terakowskiej
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Bednarek Magdalena
Published: April 2022

A Feminist Fairy-Tale? On a novel Witches’ Daughter [Córka Czarownic] by Dorota Terakowska Highly awarded novel by Dorota Terakowska, Witches’ Daughter [Córka Czarownic], is considered by many critics as a piece of a YA feminist writing. The article asks not only if feminist ideas could be present in the novel written in 1988 but also if it could be seen as emancipatory by Polish readers after socio-political transformation (the novel was published for the first time in 1991). The author recreates three contexts to consider this possibilities: formal, socio-cultural and socio-political. Analysis of style, chronotop and characters of the novel prove that fairy-tale elements are only an ornaments in the novel, not always harmonically used in it. The statements about the female fairy tale made by I. Dan and S.S. Jones leads the author to a recognition that structure of a plot in Terakowska’s novel follows not female, but male script of the initiation present in the fairy tales. The socio-political transformation which took place in Poland in 1989 is a milestone put between the writing and publishing of the novel. Changes in women’s rights and women’s movement transformed the ideas that could have been read in 1988 as emancipatory into the backlash traits.
Samodzielne i samotne. O (nie)grzecznych dziewczynkach w prozie dla dzieci Doroty Terakowskiej
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Kwiatkowska Agnieszka
Published: April 2022

Independent and lonely. About polite and naughty girls in the prose for children by Dorota Terakowska The article is an attempt at discussing the construction of heroines in the prose of Dorota Terakowska. These are usually independent and mature girls who rebel against the surrounding evil and against the rules imposed by their carers. Terakowska’s novels are directly targeted at their audience and refer to its experiences. By identifying themselves with the heroines of the story, readers can readily name their own emotions and overcome the sense of loneliness. The autobiographical character of many of the themes allows for the building of a special bond between the author and the audience, which, in turn, contributes to the building of an inter-generational community.
Dorota Terakowska. Między literaturą a dziennikarstwem – w poszukiwaniu autorskiego idiolektu
Authors:   Uniwersytet Wrocławski, Ługowska Jolanta
Published: April 2022

Dorota Terakowska. Between literature and journalism – in search of the author’s idiolect Before Dorota Terakowska explored fiction in her works, her “profession” was journalism, with which she did not part for the rest of her life. Journalism gave her the opportunity to shape the attitudes of readers, influence the choices they make, persuade them to follow a lifestyle she valued. A hallmark of Terakowska’s journalistic style is her constant willingness to use the presented events and situations, the observed “here and now,” to formulate more general patterns of behaviour, her ability to diagnose the current state of the society; her experience gained in the course of sociological studies was undoubtedly useful. Terakowska was also aware of the persuasive function of words, which is visible in, e.g., in the aphoristic character of the writer’s style, her preference to use statements that could become highly readable and evocative for the intended recipient thanks to the author’s intent. These properties of Terakowska’s idiolect may be observed both in her journalism (e.g., in the columns in the “Elle” magazine) and her fiction works. The protagonists in Lord of the Lewaw [Władca Lewawu], Mirror of Mr. Gryms [Lustro pana Grymsa] and Witches’ Daughter [Córka Czarownic] – resonating characters, often porte-parole of the author, are formulating (regardless of their young age!) maxims worthy of a sociologist or even a philosopher, maturely and courageously conversing with persons representing views different from their own. Thus, these protagonists unveil a special kind of power of each word, its specific pragmatic function expressed in the ability to shape attitudes, influence future decisions.
Ona i Ono – przedwczesne macierzyństwo w polskiej literaturze młodzieżowej
Authors:   Uniwersytet Jagielloński, Pielorz Dorota
Published: April 2022

She and It [Ono] – Premature motherhood in Polish youth literature This article concerns ways of portraying premature motherhood in Polish youth literature at the turn of the 21st century. Firstly, this problem is characterized in relation to the psychological lifespan theory and the concept of unpunctual events. Then, the author discusses a number of books in which the central figure is a pregnant teenage girl and describes the image of the heroine and her environment depicted in these books. Compared with sociological and psychological research, the analyzed books are proved not to show the reality as it is. Therefore, in the article, the author tries to point out some possible reasons and consequences of this dichotomy. Dorota Terakowska’s It [Ono] is presented against the background of those books, as it markedly distinguishes itself from the other pieces of Polish youth literature that portray a teenage mother.
The Association of Caregiver Characteristics and Caregivers’ Perceived Difficulty in Medication Management Tasks
Authors: Li Niying , Look Kevin A.
Published: April 2022

Background: Medication management tasks are commonly performed by family caregivers caring for patients with dementia, but caregivers also reported difficulties in performing these tasks.
Objectives: Using the 2017 National Study of Caregiving (NSOC) and the 2017 National Health and Aging Trends Study (NHATS), this study examined the association between caregiver characteristics and caregiver difficulty in performing medication management tasks (e.g., ordering medications, keeping track of medications, giving shots).
Methods: The main independent variable was the number of medication management tasks performed by the caregivers. The dependent variable was difficulty in performing medication management tasks. Other variables of interest included caregiver age, sex, education, co-residence with the care recipient, and use of support services. This study used the Pearlin’s Stress and Coping Model to select other control variables from hundreds of variables contained in the NSOC. A lasso logistic regression model was used to account for the large amount of other control variables.
Results: Caregiver difficulty was found mainly in keeping track of medications or giving shots (42.4%). More medication management tasks were significantly related to caregiver difficulty [OR=2.71; 95% CI (1.84 - 3.99)]. A significant association linking support service use with task difficulty was also observed [OR=1.82; 95% CI (1.06 - 3.13)], which warrants additional research.
Conclusions: Caregiver difficulty was found mainly in keeping track of medications or giving shots. More medication management tasks were significantly related to caregiver difficulty. Since patients with dementia are often on multiple medications, it is crucial to ensure medication management is done correctly to avoid adverse health consequences.
Shifts in Pharmacists’ Responsibilities in Family Medicine Residency Programs during COVID-19
Authors: Montag Schafer Katherine , Harris Ila , Lounsbery Jody , Philbrick Ann M. , Moon Jean
Published: April 2022

Background: The role of clinical pharmacists in family medicine residency programs (FMRPs) has become increasingly commonplace in the last several years, with mixed responsibilities, however largely involving teaching and patient care. The COVID-19 pandemic affected all facets of healthcare, pharmacists included. Assessment of the impact of COVID-19 on the role of the pharmacist in FMRPs is needed.
Methods: A survey tool was developed and distributed through two national listservs clinical pharmacists in FMRPs commonly subscribe to.
Results: A total of 32 responses were received. The majority of pharmacist participants indicated no change in their overall time allocation to the FMRP. Patient care was affected by transitions to virtual or remote care for those in the outpatient setting, which in some cases were sustained changes. Teaching responsibilities increased for the majority, largely impacted by the need to transition to virtual platforms. Barriers to relationship development resulted from both of these transitions. Innovations and positive results were reported by participants in patient care, teaching, and research.
Conclusions: These results highlight the many silver linings of the COVID-19 pandemic. The new challenges, such as the increased teaching need, use of virtual platforms and using creative ways to find connections and build relationships in an ongoing, semi-virtual world, are opportunities for continued innovation for clinical pharmacists as they fit within our strengths and scope within FMRPs.
El nivel de puesto de trabajo y el grado personal con referencia a la función pública local de Canarias
Authors: López González Antonio Miguel
Published: April 2022

El presente estudio tiene como objetivo: 1. analizar la figura jurídica del nivel de puesto de trabajo, desde el punto de vista de su utilidad para el ejercicio de la potestad de autoorganización en materia de ordenación del personal y del derecho a su promoción profesional; 2. extraer, del conjunto del ordenamiento jurídico, aquellos hechos determinantes del ejercicio y control de legalidad de la discrecionalidad administrativa, inherente a dicha potestad de autoorganización, cuando se aplica a determinar y motivar el nivel de puesto de trabajo; y 3. todo ello, combinando el Derecho de Función Pública Estatal Básico y el Autonómico de Canarias, aplicables a la función pública local canaria.
González Ríos, Isabel, Los Entes Locales ante la transición y sostenibilidad energética. Nuevos desafíos jurídicosadministrativos para 2030-2050
Authors: Avila Rodríguez Carmen María
Published: April 2022

Recensión del libro de González Ríos, Isabel: Los Entes Locales ante la transición y sostenibilidadenergética. Nuevos desafíos jurídicos-administrativos para 2030-2050.Thomson Reuters Aranzadi. 2021. 423 pp. Prólogo Ángel Sánchez Blanco.Esta obra analiza, de forma rigurosa y completa, las distintas competencias y el papel que los entes locales tienen que asumir para ser los auténticos protagonistas de la transición justa energética que nos conduzcan a la descarbonización de la economía. La autora presenta interesantes críticas al régimen jurídico vigente y nuevas propuestas lege ferenda.
BILANGAN RAMSEY MULTIPARTIT HIMPUNAN UNTUK KOMBINASI GRAF LINTASAN $P_3$ DENGAN GRAF POHON
Authors: Mardhiyah Asyraf , EFFENDI EFFENDI , SY SYAFRIZAL
Published: April 2022

Misalkan K_{k x j} notasi dari graf multipartit seimbang lengkap yang terdiri dari k himpunan partit yang setiap partit memuat j titik, setiap titik bertetangga kecuali pada himpunan partit yang sama. Misalkan j>= 2 adalah bilangan asli. Untuk graf G dan H, bilangan Ramsey multipartit himpunan M_j(G,H) adalah bilangan asli terkecil p sedemikian sehingga setiap pewarnaan merah-biru pada sisi K_{kx j} senantiasa terdapat G berwarna merah atau H bewarna biru sebagai subgraf. Dalam penulisan ini, penulis menentukan nilai-nilai dari bilangan Ramsey multipartit himpunan M_j(G,H) dimana G adalah graf lintasan P_3 dan H adalah graf pohon T_n.
Fuzzy Time Series Orde Tinggi berdasarkan Rasio Interval
Authors: Vianita Etna , Tjahjana Redemtus Heru , Udjiani Titi
Published: April 2022

Fuzzy time series (FTS) adalah metode peramalan untuk memprediksi data time series dibentuk dalam nilai-nilai linguistik yang diperkenalkan pertama kali oleh Song dan Chissom. Metode peramalan FTS terus berkembang misalnya pengembangan pada partisi interval pembicaraan menggunakan rasio interval oleh Huarng dan pengembangan pada fuzzy logical relationship (FLR) orde tinggi oleh Chen. Penelitian ini memodifikasi metode Chen pada langkah partisi interval pembicaraan menggunakan rasio interval untuk meningkatkan akurasi peramalan. Langkah pertama adalah pembentukan semesta pembicaraan. Kedua, mempartisi semesta pembicaraan menjadi beberapa interval dengan menggunakan rasio interval. Ketiga, fuzzyfikasi. Keempat, membangun relasi logika fuzzy (FLR) dan grup relasi logika fuzzy (FLRG). Kelima, defuzzyfikasi. Hasil penggabungan metode Huarng-Chen dibandingkan dengan metode Chen. Simulasi yang dilakukan menggunakan data produksi karet Indonesia tahun 2000-2020. Hasil dan eror dari metode diuji menggunakan mean square error (MSE) dan average forecasting error rate (AFER). Diperoleh hasil modifikasi menghasilkan eror yang lebih kecil daripada metode sebelumnya.
FAKTOR-FAKTOR YANG MEMPENGARUHI MASA STUDI DAN INDEKS PRESTASI KUMULATIF MAHASISWA DENGAN MODEL REGRESI LOGISTIK BINER BIVARIAT
Authors: Yelfera Siti Rani , YOZZA HAZMIRA , RAHMI HG IZZATI
Published: April 2022

Mutu lulusan suatu perguruan tinggi biasanya sering diukur dari Indeks Prestasi dan masa studi mahasiswa. Pencapaian prestasi akademik mahasiswa dan masaÂ studinya dipengaruhi oleh berbagai faktor baik itu faktor internal maupun faktor eksternal. Pada penelitian ini dilakukan analisis faktor-faktor yang mempengaruhi masa studi dan Indeks Prestasi Kumulatif mahasiswa Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Andalas. Metode yang digunakan adalah regresi logistik biner bivariat. Hasil penelitian ini menunjukkan bahwa dari 15 variabel prediktor yang digunakan yaitu variabel jalur masuk, pilihan jurusan saat mendaftar Universitas Andalas, minat terhadap jurusan, bakat terhadap jurusan, tempat tinggal, biaya hidup perbulan, status penerima beasiswa, metode belajar, dukungan sosial, dukungan keluarga, keaktifan organisasi motivasi belajar, gaya belajar, kondisi kesehatan dan mental, dan fasilitas layanan akademik hanya ada dua variabel prediktor yang signififikan mempengaruhi masa studi dan Indeks Prestasi Kumulatif mahasiswa yaitu variabel jalur masuk dan motivasi belajar.Kata Kunci: masa studi, Indeks Prestasi Kumulatif, regresi logistik biner bivariat.Â
El fenómeno de la poesía juvenil o joven poesía pop a la luz de la Teoría de los Polisistemas
Authors: Suárez Hernán Carolina
Published: April 2022

Este trabajo pretende analizar el fenómeno de la joven poesía o poesía juvenil pop surgida al calor de las redes sociales en la reciente década bajo el prisma de la Teoría de los Polisistemas. El sistema literario y, concretamente, el ámbito poético experimenta en los últimos años interesantes desplazamientos y tensiones que han generado debates y que pueden y deben ser analizados con diferentes herramientas. La joven y nueva poesía se ha venido gestando al margen de los circuitos editoriales tradicionales y, además, presenta la particularidad de integrar un componente femenino sustancialmente más representativo que el que presentaban otros estadios del sistema poético, algo a lo que también debe prestarse la debida atención.Por tanto, el objetivo que nos proponemos es arrojar luz a los entrecruzamientos y desplazamientos que se producen entre el sistema poético central y el sistema poético juvenil y otros periféricos analizando las modificaciones en los distintos elementos de los sistemas mencionados.
María José Ragué Arias, pionera en el estudio del teatro contemporáneo hispánico y catalán con perspectiva de género
Authors:   Universitat de Barcelona (España), Nicolau Jiménez Adriana
Published: April 2022

María José Ragué Arias (Barcelona 1941-2019) was a Catalan scholar, theatre critic, playwright and feminist activist. This article focuses on a particular aspect of Ragué’s career: her contributions to the study of contemporary Hispanic and Catalan theatre from a feminist perspective. Following an overview of her intellectual career, this article explores the different aspects of this part of her work: the study of the contemporary rewritings of ancient Greek theatre female characters, the reception of feminist anglophone theatre studies, the analysis of the theatre field from a gender perspective and the understanding of female authorship as a differential value. The ensemble of these contributions represents a pioneer approach to contemporary theatre within the late 20th century Spanish academia and is still current at multiple levels, standing as a referent to claim for the study of the relationships among gender, feminisms, women and theatre in the 21st Century.
«Sendero Fortún»: María Folguera y el teatro como investigación
Authors:   European University Institute (Italia), Monmeneu González Mónica
Published: April 2022

From November 2019 to March 2020 the Valle-Inclán Theatre in Madrid hosted «Sendero Fortún», a theatrical diptych integrated by Celia en la Revolución and Elena Fortún, aimed to recover and disseminate the figure of Encarnación Aragoneses –alias Elena Fortún– and her work. Through the text and direction of Elena Fortún, María Folguera uses the theatrical device as means to develop a research project that emanates from the revision of Elena Fortún’s public and private texts, postulating itself as a new source of study of the author and her context. This article analyzes the twofold results of Folguera’s work: on the one hand, the posing of a series of observations about the act of writing and female authorship; and on the other, how this necessarily relates to the creation of a collective memory of characters and places pivotal to the life and times of Fortún, among which the importance of the Lyceum Club and its environment stand out.
Firmado Lejárraga, de Vanessa Montfort: la «autorización» de una escritora fantasma
Authors:   Universidad de La Laguna (España), Acosta Mota Alejandra , Castells Molina Isabel ,   Universidad de La Laguna (España)
Published: April 2022

In this article we intend to address the recovery of the authorial figure of one of the most important playwrights of the Spanish Silver Age, through the play by Vanessa Montfort entitled Firmado Lejárraga. To do this, we will first review the main aspects of the concealment of María Lejárraga’s authorship under the Martínez Sierra trademark and how they are reflected in the play. Secondly, we will focus on the specific elements of the dramaturgy proposed by Vanessa Montfort, highlighting her metafictional approach and also paying attention to other works by the author, especially the novel Una mujer sin nombre. Thus, we will try to see how fiction can serve as an effective and necessary process of «authorization», which completes our cultural history by adding the fundamental contribution of female writing
«Performance, horror y cuento»: la dramaturgia de Angélica Liddell y María Folguera
Authors:   Universidad Complutense de Madrid (España), Fernández Suárez Laura
Published: April 2022

Our article will analyze the work Y como no se pudrió... Blancanieves (Artezblai, 2007) by Angélica Liddell (Figueras, 1966) and the work Hilo debajo del agua (Ediciones La Complutense, 2010) by María Folguera (Madrid, 1984). These two works summarize some of the most important characteristics of the production of its authors. On the one hand, the Art of Performance, as a source of inspiration and/or as a tool for staging. On the other hand, the use of the narrative techniques of the tale in his dramaturgy and, finally, the denunciation of the human cruelty of our time. We will analyze the contrasts and similarities between the two works, how the traces of the performance are perceived, what concrete events animated these creations, how they make use of the genre of the tale and what kind of theater results from this wonderful miscellany.
Construções metafóricas na narrativa da criança
Authors: Golembieski Gabriela
Published: April 2022

Neste trabalho, busca-se descrever como se estabelecem as metáforas, concebidas como “transferências analógicas de denominações” (cfe. BENVENISTE, 2020), nos deslocamentos realizados pela criança na linguagem. O viés teórico-metodológico pauta-se na perspectiva enunciativa aquisicional (SILVA, 2009), a qual se baseia em princípios benvenistianos. Neste artigo, ilustra-se o tema com um dado de uma criança de 5 anos. O objetivo é  descrever como se estabelecem as “transferências analógicas de denominações” nos deslocamentos realizados pela criança na linguagem. Compreende-se a metáfora como um arranjo de formas e sentidos que se estabelece no uso da língua pelo falante em determinada situação enunciativa e na relação intersubjetiva com o outro da enunciação. Nas vivências com o outro,  na cultura da sociedade da qual faz parte, a criança vivencia o poder de significação advindo da propriedade simbólica da linguagem, o que lhe permite estabelecer analogias entre formas e sentidos da língua e mobilizar, no discurso, novos empregos para palavras e expressões da língua.
Two-gaps microwave ion engine and its study by aerodynamic method
Authors:   Omsk State Technical University, Vavilov I. S. , Yachmenev P. S. ,   Omsk State Technical University, Fedyanin V. V. ,   Omsk State Technical University, Zharikov K. I. ,   Omsk State Technical University, Stepen P. V. ,   Omsk State Technical University, Lukyanchuk A. I. ,   Omsk State Technical University, Kuzmenko I. A. ,   Omsk State Technical University
Published: April 2022

The article contains the authors’ research in the field of jet propulsion systems with low energy consumption of small spacecraft of the class of nanosatellites. The paper presents a microwave ion engine with double acceleration of ionized gas in the gaps formed by the end surfaces of cylindrical resonators. The results of an experimental study of the pressure force of a jet set of ionized gas by the aerodynamic double angle method are presented. A stand for determining the power parameters of week plasmajet is presented. The design of the prototype is presented. The total energy consumption of the prototype is 5 watts, the accelerated gas flow rate is up to 200 km/s, the jet pressure force on the sensing element of the stand is 0,1 μN. The working body of the prototype is nitrogen at a pressure in a vacuum chamber of 18 Pa.
Pulmonary rehabilitation implementation in Northwest Nigeria: A qualitative study of the views of respiratory health-care professionals
Authors: Babaji Hafsat Umar , Sulaiman Surajo Kamilu , Shittu Aishat , Abubakar Yakubu , Mohammed Jibril
Published: April 2022

Objectives:

Pulmonary rehabilitation (PR) service is a comprehensive program comprising both pharmacological and non-pharmacological (exercise training, counseling, nutritional, etc.) treatment options that have been proven to improve physical and psychological conditions of patients with chronic respiratory diseases (CRDs). Nevertheless, PR is non-existent in most parts of Africa. The objective of this study is to report on the views of respiratory health professionals (pulmonologists and allied health) regarding the implementation of PR in Northwest Nigeria.

Materials and Methods:

Using a qualitative descriptive design, a group of 11 purposively sampled respiratory health professionals working in tertiary hospitals in Northwest Nigeria was contacted to participate in the study. Semi-structured in-depth interviews were conducted with the participants. Information power was used to stop data collection. The data obtained were analyzed using thematic synthesis.

Results:

Six themes emerged from the interviews as follows: (i) Description of PR as a comprehensive life-saving intervention that involves exercises, education, self-care, and nutrition; (ii) absence of PR units; (iii) possession of knowledge of their roles; (iv) possession of basic knowledge of roles of other team members; (v) lack of specialized workforce; and (vi) lack of facilities and equipment. In general, the results of the study indicated that some respondents were more conversant with PR as an intervention in CRDs than others. Furthermore, the respondents had basic knowledge of the roles of other professionals in the delivery of PR. Finally, the major barriers to the utilization of PR services were poor awareness, lack of equipment, and workforce.

Conclusion:

There was a general lack of comprehensive PR services in the study area with respiratory health-care professionals demonstrating variable, but mostly good knowledge of PR.
Case Report of CT Findings in Post Partum Renal Cortical Necrosis
Authors:   Department of Radiodiagnosis, Dr. Ram Manohar Lohia Institute of Medical Science, Lucknow, India, S Neha , RA Gaurav ,   Department of Radiodiagnosis, Dr. Ram Manohar Lohia Institute of Medical Science, Lucknow, India, L Ankur ,   Department of Skin and Venerology, VMMC Safdarjung, New Delhi, India, S Ankur ,   Department of Radiodiagnosis, Dr. Ram Manohar Lohia Institute of Medical Science, Lucknow, India
Published: April 2022

Renal cortical necrosis is ischemic destruction of renal cortex which can be patchy or diffuse caused by significantly reduced arterial perfusion. In addition, direct endothelial injury particularly in setting of sepsis, eclampsia, haemolytic uremic syndrome (HUS) and snake bite may lead to renal ischemia caused by endovascular thrombosis. Progression to end stage renal disease is a rule in diffuse cortical necrosis [1].
Carbon dioxide fixation in RuBisCO is protonation state dependent and irreversible
Authors: Douglas-Gallardo Oscar , Murillo Juliana , Oller Javier , Mulholland Adrian , Vöhringer-Martinez Esteban
Published: April 2022

Most CO2 from the atmosphere is assimilated in photosynthetic organisms by the ribulose 1,5-bisphosphate carboxylase-oxygenase (RuBisCO) enzyme as part of the Calvin cycle. Despite its relevance and many efforts in the last few decades, the mechanistic picture of the catalytic CO2 fixation reaction is still under debate. Here, we combine QM/MM molecular dynamics simulations with high-level electronic structure methods and the projector-embedding approach to provide reference values for the activation and reaction free energies of the catalytic CO2 fixation reaction. Our results show that carboxylation is protonation state dependent and irreversible, making the back reaction (decarboxylation reaction) highly unfavourable. The carbamylated lysine residue, Kcx201, coordinated to the magnesium (II) cation in the active site plays a central role shuffling protons from and to the substrate creating the proper reactive enolate species that adds CO2. The emerging microscopic picture that involves several protonation equilibria and the free energy profile of the CO2 fixation reaction provides insights that may be used in the future to improve enzymatic efficiency in RuBisCO.
Population and Coherence Dynamics in Large Conjugated Porphyrin Nanorings
Authors: Bressan Giovanni , Jirasek Michael , Anderson Harry L. , Meech Stephen R. , Heisler Ismael A.
Published: April 2022

In photosynthesis nature exploits the distinctive electronic properties of chromophores arranged in supramolecular rings for efficient light harvesting. Among synthetic supramolecular cyclic structures, porphyrin nanorings have attracted considerable attention as they have a resemblance to naturally occurring light-harvesting structures but offer the ability to control ring size and the level of disorder. Here, broadband femtosecond transient absorption spectroscopy, with pump pulses in resonance with either the high or the low energy sides of the inhomogeneously broadened absorption spectrum, is used to study the population dynamics and ground and excited state vibrational coherence in large porphyrin nanorings. A series of fully conjugated, alkyne bridged, nanorings constituted of between ten and forty porphyrin units is studied. Pump-wavelength dependent fast spectral evolution is observed. A fast rise or decay of the stimulated emission are observed when large porphyrin nanorings are excited on, respectively, the high or low energy side of the absorption spectrum. Such dynamics are consistent with the hypothesis of a variation in transition dipole moment across the inhomogeneously broadened ground state ensemble. Oscillatory dynamics on the sub-ps time domain are observed in both pumping conditions. A combined analysis of the excitation wavelength-dependent transient spectra along with the amplitude and phase evolution of the oscillations allows assignment to vibrational wavepackets evolving on either ground or excited states electronic potential energy surfaces. Even though porphyrin nanorings support highly delocalized electronic wavefunctions, with coherence length spanning tens of chromophores, the measured vibrational coherences remain localised on the monomers. The main contributions to the beatings are assigned to two vibrational modes localised on the porphyrin cores: a Zn-N stretching mode and a skeletal methinic/pyrrolic C-C stretching and in-plane bending mode.
C3–H Silylation of Furfural Derivatives: Direct Access to a Versatile Synthetic Platform Derived from Biomass
Authors: Curpanen Sébastien , Poli Giovanni , Perez-Luna Alejandro , Oble Julie
Published: April 2022

The sustainable production of industry-relevant chemicals, ranging from biofuels to pharmaceuticals, requires the development of efficient functionalization of biomass-derived building blocks, such as furan derivatives. Herein we report directed iridium-catalyzed C3–H silylation of furfural compounds, which grants access to versatile synthetic platforms. This transformation was developed on furfuryl derivatives, using imines as directing groups, and trialkylsilanes or bis(trimethylsilyl)methylsilane as silylating agents, in the presence of a hydride scavenger. Subsequently, fluoride-mediated activation strategies were applied to the C3–SiMe(OSiMe3)2 furfural derivatives. This strategy enables a wide range of transformations, namely arylation, alkenylation, alkynylation, allylation and alkylation, as well as halogenation and trifluoromethylation. A variety of high value-added products were thus easily obtained from the same common C3-silylated furfural platform.
CONCEPTOS CLAVES DE LA GESTIÓN CULTURAL Vol. II
Authors: Mariscal José Luis
Published: April 2022

Los términos aquí expuestos buscan dar sentido a una práctica que se viene realizando desde hace muchos años y que necesita ser pensada. No pretenden ser homogéneos y hegemónicos, sino contribuir a la reflexión de una gestión cultural que cada vez más se perfila como la posibilidad de constituirse en un referente de la acción cultural en Latinoamérica.
Counselling Services For Peace and Unity Awareness Among Youths in Niger State
Authors: Mamman Ruqayyat Momoh , Abubakar Lukman Zuba , Sarki Isah
Published: April 2022

This study investigated the role of counselling services for peace and unity awareness among youths in Minna metropolis of Niger State. Descriptive survey research was employed to collect information from the sample and conclude base on the targeted population. The population was all youth in Minna metropolis, four wards were randomly selected at twenty youths per ward, eighty youths were used for the sample. The instrument used were the tagged Questionnaire for counselling services for peace and unity awareness among youth (QCSPUAY). It was meant to measure causes of crisis, disunity, place of youth on peace and unity in our communities and the role of counsellors in creating awareness among youth in Minna metropolis. A finding of the study showed that there is severe disunity amongst the youth and that youth play a great role in influencing peace and unity in their various communities. Hence, for the sake of peace and unity, there is an urgent need for counselling services in all forms of education to expose youth to see tremendous advantages of peace and unity. Therefore, the study recommended that youth of different tribes, religions, political affiliations and social-economic status should always pursue peace and unity wherever they found themselves. Also, the services of counsellors should focus on creating awareness that will assist in influencing youth towards embracing peace and unity.
Use of organic acid blends to control spread of salmonella heidelberg in broilers
Authors: Sausen Lourenço , Signor Mendes Angélica , Refatti Sikorski Rosana , Uliana Rosiane de Fátima , Ferreira Zago Cláudia Helena , Trevisan Lucas Renato , Evangelista Guimarães Bruno
Published: April 2022

The objective was to evaluate an organic acid blend supplied via water and feed to control the spread of Salmonella Heidelberg in broilers from 1-31 days of age. The design was a complete randomized block with five treatments and five replicates, 25 experimental units (13 birds per unit, density of 13 birds/m2). 325 one day old female chicks were randomly arranged in five treatments: T1 - Negative Control (no acids + 0,5 ml of physiological solution in water); T2 - Positive control (no acids + 0,5 ml of Salmonella Heidelberg (1.206  CFU) in water); T3 - Via Acid water (inoculation of 0,5 ml of Salmonella Heidelberg (1.206 CFU) in water); T4 - Infeed Acid (inoculation of 0,5 ml of Salmonella Heidelberg (1.206 CFU) in feed); T5 - Acid via water and feed (inoculation of 0,5 ml of Salmonella Heidelberg (1.206   CFU)). The results were analyzed using Bayesian comparisons with 5% of significance and a priori beta distribution. Significant effects of treatments were found on feed conversion at 21, 28 and 31 days, treatment T3 had the best results. Regarding live weight, significant effects at 14, 21, 28 and 31 days were observed in T3, greater than others. The blend of organic acids has shown its numerical effectiveness in reducing the incidence of Salmonella Heidelberg among the treated groups in intestines pool at nine days, drag swab at 16 days and in wattle collection at 31 days. There were no significant differences between the treated groups and control groups.
Mieloma múltiplo não secretor em cão Shih Tzu: relato de caso
Authors: Carrera Alefe Luiz Caliani , Moreno Isabela Ferraro , Luz Marcela Baggio , Requena Ricardo , Russo Cláudia
Published: April 2022

O Mieloma Múltiplo (MM) é uma neoplasia de plasmócitos com origem na medula óssea, sendo de rara ocorrência. Na forma não-secretora não há identificação de gamopatia monoclonal sérica e da proteinúria de Bence-Jones, tornando o diagnóstico mais desafiador. Relata-se um caso de MM não-secretor, em cão da raça Shih Tzu, com histórico de hiporexia e emagrecimento progressivo sem demais manifestações clínicas. Foram encontrados em exames complementares achados inespecíficos iniciais de cardio, hepato e esplenomegalia, além de anemia. Também foram descartadas doenças infecciosas endêmicas. Por meio de radiografia de membros e coluna vertebral, foram evidenciadas lesões líticas ósseas disseminadas, sugerindo MM. Encaminhou-se o paciente para mielograma, na qual foi identificada plasmocitose reativa (>10%). Na eletroforese de proteínas séricas, obteve-se valores normais; e não houve detecção da proteinúria de Bence-Jones. Também foi identificada hipercalcemia. Por meio dos achados descritos acima, foi definido o diagnóstico em MM não-secretor. Instituiu-se o tratamento com Melfalano associado à prednisolona, com melhora do quadro clínico e ausência de efeitos colaterais por 120 dias. Concluiu-se que o MM não-secretor, embora raro, deve ser adicionado à lista de diagnósticos diferenciais em situações de sinais clínicos inespecíficos associados a distúrbios osteomedular. Bem como, o protocolo quimioterápico descrito mostrou-se eficaz como abordagem terapêutica.
Soropositividade para Actinobacillus pleuropneumoniae em suínos na fase de terminação no estado de Pernambuco
Authors: Baptista Raíssa Ivna Alquete de Arreguy , Silva Antonio Samuel Alves da , Barbosa Junior Sebastião André , Cysneiros Bárbara Costa , Barbosa Clara Nilce
Published: April 2022

O objetivo deste estudo foi avaliar a soropositividade para Actinobacillus pleuropneumoniae (App) em suínos da fase de terminação pelo teste imunoenzimático indireto (ELISA-Enzyme-Linked Immunosorbent Assay). As amostras de soros (n=153), coletadas em abatedouros, foram procedentes de municípios pernambucanos, incluindo Camaragibe, Caruaru, Gravatá, João Alfredo, Lagoa do Carro, Paudalho e São Lourenço da Mata. Os resultados revelaram 40,52% de soropositividade e todos os municípios apresentaram animais positivos. Houve diferença estatística significativa (p<0,05) entre os municípios e os resultados dos testes sorológicos. Os municípios Camaragibe, Caruaru, Gravatá e Paudalho apresentaram diferença estatística significativa (p<0,05), nas proporções de soropositividade, quando comparados com João Alfredo, Lagoa do Carro e São Lourenço da Mata. Este estudo mostra a primeira evidência de anticorpos contra App em suínos no estado de Pernambuco.
The linkage between mercury-caused neuro- and genotoxicity via the inhibition of DNA repair machinery: fish brain model
Authors: Nedzvetsky V.S. , Gasso V.Y. , Herrmann B. , Novitskiy R.O.
Published: April 2022

Heavy metals in model conditions as well as industrial pollution launch disturbances in neural cells of different animals and human beings. The neurotoxicity of mercury, which is one of the most toxic heavy metals, has been studied for several decades. However, its low doses chronic exposure effects for neural tissue cells are still poorly understood. Therefore, the basic molecular mechanisms of mercury should be clarified. The purpose of our research is to clarify the mechanism of mercury genotoxicity, the role of the DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in neural tissue cells, and the response to inorganic mercury-induced neurotoxicity. In our model, we used juvenile rainbow trout exposed to mercury chloride with a range of doses 9‑36 µg/L for 60 days to study the cytotoxicity of chronic exposure. We detected the reactive oxygen species (ROS) production as an index of oxidative stress and APE1 as a marker of cellular DNA damage response in a neural cell. The ROS level was measured by using the fluorometric method based on 2',7'-dichlorofluorescein diacetate reaction. The analyses of markers of the DNA repair (APE1) and apoptosis (B cell lymphoma-2 anti-apoptotic protein – Bcl-2) were carried out with western blotting. The mercury chloride chronic exposure induced statistically significant upregulation of the ROS production in the fish brain. Contrary, the mercury low doses stimulated the downregulation of APE1 expression in the brain tissue. Furthermore, mercury chronic exposure inhibited the expression of Bcl-2 in the animals treated with 18 and 36 µg/L mercury chloride. The harmful effect of mercury could be promoted by oxidative stress generation. The downregulation of APE1 expression could lead to a lack of DNA damage response efficacy and initiate the decline in neural cell functioning. Obtained data on the APE1 expression have shown that the neurotoxic effect of mercury could be mediated, at least partially, by the decline in cellular DNA damage response in the brain. The evaluation of decrease in DNA repair response via detection of the APE1 expression can be a prospective tool to reveal the deleterious effects of toxicants in terms of their neuro- and genotoxicity.