bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Negative career shock on employee workplace behavior through emotional exhaustion and moderated by Hostile Climate
Authors: Shafique Ayesha , Hayat Qlander , Waheed Rauza , Khan Muhammad Kamran
Published: September 2024

Purpose - Even though much research has linked effective career management to career development strategies, there is always room for improvement in this area. While career shock has been the subject of increased research as of late, little is known about how negative career shocks relate to boredom in the workplace. Using the framework of the Conservation of Resource Theory (COR), this study aims to examine the effect of a negative career shock on workplace boredom via the mediating function of emotional exhaustion and the moderating role of a hostile climate.
Design/Methodology/Approach-In Pakistan service industry play important role in the development, so the data of 245 service industry workers were taken from different levels of management in Pakistan's twin towns of Rawalpindi and Islamabad. A questionnaire with 22 items using a 7-point Likert scale was used to get responses. We utilized SPSS version 24 to analyse the results.
Findings- The findings demonstrated a positive correlation between negative career shock and boredom on the job. Both emotional exhaustion and a hostile work environment lessen the correlation between emotional exhaustion and boredom on the job.
Implications: This research adds to the growing body of knowledge on the topic of unexpected career setbacks. It also offers useful and relevant conclusions and recommendations for the future of the field of study. Employees can protect themselves from a shock in their careers by building up their skills and connections through internal opportunities for advancement through training and development.
Originality/Value- The study contributes to the career-development literature by providing a causal link between career shock and boredom through empirical analysis.
Examining The Role of Core Self Evaluation and Learning Goal Orientation in Determining Individual Ambidexterity
Authors: Awan Hadia , Kalyar Masood Nawaz , Saleem Sharjeel
Published: September 2024

Purpose-The recent astronomical growth witnessed in the study and the importance of achieving organizational ambidexterity by scholars, the ensuing focus on promoting individual ambidexterity to achieve organizational ambidexterity, and the further focus on the micro-foundations of individual ambidexterity warrants to dig deep into the factors that determine individual ambidexterity. Research has largely missed the individual differences in people that may either promote or hinder their ambidextrous behavior. The purpose of this study is to investigate the role of core self-evaluation as a broad personality trait in determining the ambidextrous behaviors of employees at an individual level. This study also investigates the role of learning goal orientation as a mediator between core self-evaluation and individual ambidexterity.
Design/Methodology/Approach-This study uses data from 396 managerial level employees collected through structured questionnaires in two waves from various organizations across multiple industries. Data is analyzed through Hayes Process Macro using SPSS and Amos v.24.
Findings -The data analysis shows that core self-evaluation has a positive impact on individual ambidexterity and that learning goal orientation mediates the relationship between core self-evaluation and individual ambidexterity.
Practical Implications-This study offers significant implications for human resource managers and top management of the organization by highlighting the importance of selecting employees with positive core self-evaluation and the importance of encouraging those employees to set learning-oriented goals.
Originality/Value-Very few researchers have studied the impact of the personality trait of core self-evaluation on complex but desired behavioural outcomes in organizations. The individual differences between employees play an important role in their behavioural manifestations, hence, understanding the differences is crucial to achieving goals and success. This study positively contributes to the literature on core self-evaluation and individual ambidexterity by demonstrating a positive link between them.
Comparison of Intravenous Lignocaine and Intravenous Dexmedetomidine for Attenuation of Hemodynamic Stress Response to Laryngoscopy and Endotracheal Intubation
Authors: Sana Tariq  , Khan Muhammad Yaqoob  , Arooj Shahid  , Komail Abid  , Muhammad Mughal Ul Haq
Published: September 2024

Objective: To compare the efficacy of Lignocaine and Dexmedetomidine in minimizing the hemodynamic stress response associated with laryngoscopy and endotracheal intubation.
Study Design: quasi-experimental study.
Place and Duration of Study: Department of Anesthesiology, Combined Military Hospital Rawalpindi, Pakistan, from Jul 2020 to Feb 2021.
Methodology: A total of 60 patients, aged 18-55 years were included in this study. They were randomly allocated to one of two groups. Group-L received intravenous Lignocaine, 1.5 mg/kg. Group-D received Dexmedetomidine 1 µg/kg as intravenous infusion 10 minutes before induction. Heart rate and mean arterial pressure were monitored at basal, pre-induction, induction, laryngoscopy and intubation and 1, 3, 5 and 10 minutes afterwards.
Results: Significantly reduced stress response was seen in Group-D as compared to Group-L. A lesser increase in heart rate was observed during intubation as compared to basal level in Group-D (14.14%) while it was 37.66% in Group-L. MAP was also seen to be less increased in Group-D (1.07 %) as compared to Group-L (22.6%).
Conclusion: Dexmedetomidine, when infused at a dose of 1 mcg/kg over 10 min prior to intubation, attenuates the hemodynamic stress response more efficiently, in comparison to 1.5 mg/kg of Lignocaine infusion.
Who Gains from Nonviolent Action? Unpacking the Logics of Civil Resistance
Authors: Amat Consuelo , Trilling Claire
Published: September 2024

Research in conflict studies comparing nonviolent and violent collective action has gained widespread attention due to the counterintuitive finding that nonviolent movements succeed more often than armed movements. However, rising repression and authoritarianism worldwide, alongside
declining success rates for protest movements, highlight the need to further theorize and test the conditions under which nonviolent action succeeds. This article distills the different logics by which excluded minorities are advantaged or disadvantaged in nonviolent action. It also reviews
three new books that advance the field of movement effectiveness in the short and long runs, and that demonstrate that success is context-dependent, with few characteristics universally conferring advantage or disadvantage. We conclude by outlining areas for future research, including the
role of digital technologies.
Qual o lugar da branquitude na educação cearense? Percepções discente e docente de ser branca/o nesse lugar
Authors: Oliveira Anderson
Published: September 2024

A desigualdade racial entre estudantes negros e brancos é um dado cristalizado em pesquisas educacionais (Hasenbalg, 1980; Munanga, 2000; Oliveira, 2019). Durante um tempo considerável, o sujeito negro se tornou objeto de pesquisa para observar essas lacunas entre esses dois grupos raciais. Entretanto, o movimento de pensar o outro personagem das relações raciais – o branco – tem se tornado uma tônica presente nos estudos étnico-raciais, a fim de viabilizá-lo e problematizá-lo nesse debate, campo esse denominado de estudos críticos da branquitude (Ramos, 1995; Cardoso, 2008; Bento, 2002). Nesse sentido, a fim de contribuir com a discussão, o presente artigo tem como objetivo pensar como estudantes brancos de duas escolas públicas de ensino médio do estado do Ceará compreendem sua raça nesse espaço. Além disso, metodologicamente, a observação participante (Caldwell; Atwal, 2005) foi necessária, bem como a realização de entrevistas semiestruturadas (Triviños, 1987) com estudantes que se autodeclaram brancos. Como resultado preliminar, observou-se que, tanto na escola A quanto na B, ainda não existem discussões cristalizadas a respeito do privilégio de pessoas brancas na sociedade. Além disso, percebeu-se que, apenas em uma das instituições, há uma percepção de privilégios, sejam eles materiais ou simbólicos, porém perceptíveis na instituição escolar, como resultado de notas em avaliações.
Defining European Union’s Energy Security from the Perspective of 4A (Availability, Accessibility, Acceptability, Affordability) as an Impact from Russia-Ukraine’s Conflict
Authors: Budiman Nuans Asa S , Ramadhan Iqbal
Published: September 2024

Energy issues become one of dilemma of European Union in Rusia invasion to Ukraine.  The author of this scientific study analyzes European Union policy using Benjamin Sovacool's idea of energy security, including availability, accessibility, acceptability, and affordability. To explore this phenomenon, the author used qualitative research techniques and internet-based research. This study demonstrates how the European Union is putting numerous policies into practice to reduce energy scarcity by seeking out nations that can cooperate with them in the production of oil and gas, like Algeria, Qatar, and Norway. The European Union is also building a network of infrastructure for the distribution of gas and oil so that people in the area may access and affordably buy energy sources. By maximizing renewable energy, the European Union is diversifying its energy mix and reducing its reliance on imports of gas and oil.
The history of representatives of the genus Rhododendron L. and prospects for their use
Authors:   RGAU-MSHA named after K.A. Timiryazev, Ajam Batoul , Kozlova Elena
Published: September 2024

Rhododendrons Rhododendron L. are appreciated for their high decorative value, they are of scientific and practical interest. This genus includes about 1300 wild species and more than 10,000 varieties, represented by evergreen, semi-evergreen and deciduous shrubs, shrubs and rarely trees. This article presents brief facts about the history of the emergence of the rhododendron culture. A brief description of some species and varieties of rhododendrons is presented in terms of their decorative features, with the aim of further selection and use in in-vitro culture. Keywords: INTRODUCTION OF RHODODENDRONS, TYPES OF RHODODENDRONS, WINTER HARDINESS, VARIETIES OF RHODODENDRONS
Original Extension of a Human-Oriented Benefits Platform Using BI And AI For Human Resources Management
Authors: MIŁEK Marzenna , PROTASOWICKI Tomasz , ŻMIGRODZKA Małgorzata
Published: September 2024

The purpose of this article is to present a possibility a platform that is designed for effective human resource management using BI (Business Intelligence) and AI (Artificial Intelligence) human-centric solutions. In particular, this applies to the possibility of extending Carrotspot’s existing benefit platform with a new functional scope using BI. In the literature we can find the examples of applications of artificial intelligence algorithms to the management of the organization however, they do not exhaust the topic presented in the article. The paper was prepared with the use of the critical literature review method mainly in the field of safety culture in aviation and how to manage this problem. The study was also conducted on the basis of the analysis of the capabilities of the Carrotspot’s platform in the field of aviation. Its unique solutions provide a much larger field of development than the previously described research results presented in the available literature. In the article, the authors included the studied phenomenon in a special way taking into account the implementation of the project and an attempt to implement it in the aviation environment in the field of human resource management and the creation of a safety culture using the tools available on the platform.
High risk mitigation measures in the Artificial Intelligence Regulation
Authors: Czaja Jarosław
Published: September 2024

The aim of the article is to determine the extent to which the Artificial Intelligence Regulation of March 13, 2024 (Artificial Intelligence Act) limits the risk of using products in which artificial intelligence systems are used. This is important because it has been considered a source of danger (e.g. UN resolution on AI security of March 21, 2024). The issue of an extensive scope of regulations in the process of designing and developing systems to ensure safety is also considered, which includes a number of obligations imposed on a broadly defined group of responsible entities. This act very carefully introduces, in some areas, a number of legal measures to counteract broadly understood product risk.
The Limits of Academic Freedom
Authors: Huffman James
Published: September 2024

Law school dean James Huffman suggests that academic freedom is widely misinterpreted to mean there are no limits on professorial behavior.
Two Good Words for Colonialism: Hong Kong
Authors: Beauchamp Gorman
Published: September 2024

A recent book about Hong Kong reminds a literary scholar of his time, fresh out of college, teaching English in the vibrant and spirited British colony.
Diverse Identities Are Irrelevant to Science
Authors: Staddon John
Published: September 2024

Duke Psychologist John Staddon says there is little evidence that demographic diversity strengthens scientific research.
The Full Spectrum of Humanity
Authors: Iannone Carol
Published: September 2024

Editor's introduction to the Fall 2023 issue.
The American Psychological Association’s Abortion Bias
Authors: Schmithorst Victor
Published: September 2024

Rather than furthering psychology’s status as a science and relevant field of healthcare, the APA functions as a political apparatus for progressive causes.
ESTUDO EPIDEMIOLÓGICO DOS CASOS DE OSTEOMIELITE NO PERÍODO DE JANEIRO DE 2019 A DEZEMBRO DE 2023 NO ESTADO DE MINAS GERAIS
Authors: Pires Tayná Vieira , Pinheiro Arthur Oliveira , Silva Alan Ferreira , Tabet João Pedro Almeida , Jesus Filho Arnaldo Gonçalves de , Pereira Gabriel Meireles Azevedo
Published: September 2024

Objetivo: Avaliar dados epidemiológicos relacionados a osteomielite no Sistema único de Saúde em Minas Gerais por um período de 5 anos. Método: Coorte retrospectiva, analisando prontuários eletrônicos de pacientes internados pelo SUS, nos estados brasileiros, de janeiro de 2019 a dezembro de 2023, diagnosticados com osteomielite e contabilizados no formulário eletrônico do DATASUS com as informações disponíveis no TABNET. Para o desenvolvimento e discussão teórica dos dados foram utilizados artigos científicos e bibliografias publicadas sobre o tema “osteomielite”. As pesquisas foram realizadas na base de dados da SCIELO e PubMed por meio dos descritores “osteomielite“, “Etiologia da osteomielite“, “mortalidade da osteomielite” e “Epidemiologia da osteomielite”. Resultados: Um total de 9631 internações hospitalares foi registrado, a maioria das internações concentrou-se na faixa etária de 20 a 59 anos, representando 62,4% do total. Os homens foram mais frequentemente internados, totalizando 70,7% dos casos. Ocorreram 138 óbitos por osteomielite, representando 1,43% das internações, sendo mais comum em pessoas com mais de 60 anos, que totalizaram 1,14% das internações. Conclusão: A osteomielite é um dos maiores desafios ortopédicos no país, sendo necessário, maiores investimentos no estudo, tratamento e, principalmente, prevenção dessa patologia.
The Long Road to Entertainment Radio Broadcasting in Germany
Authors: Mathis Wolfgang
Published: September 2024

Abstract. In 2023, the 100th birthday of “Unterhaltungs-Rundfunk” (Entertainment Radio Broadcasting) in Germany was celebrated with numerous special exhibitions and contributions in the press, radio and television. In this context, details on the historical development of this communication medium were also presented. It was not uncommon for references to be made to statements by Hans Bredow, the so-called “Vater des Rundfunks” (Father of Rundfunk), who as State Secretary in the Postal Ministry was responsible for organizing wireless technology in Germany after the First World War. In this article we examine the question of why broadcasting was introduced relatively late in Germany compared to other technically highly developed countries such as the United States, England and France. In order to get closer to a coherent answer based on the current state of entertainment broadcasting history in Germany, it is also necessary to draw on historical sources that do not assume a Bredow-centered perspective. In particular, Bredow's use of the term “Rundfunk” for different communication systems that were developed in Germany during and after the First World War contributed to understanding the road to “Unterhaltungs-Rundfunk” as a linear historical development, which was not the case.
Distinct changes in carbon, nitrogen, and phosphorus cycling in the litter layer across two contrasting forest-tundra ecotones
Authors: Hagedorn Frank , Imboden Joesphine , Moiseev Pavel , Gao Decai , Frossard Emmanuel , Christen Daniel , Gavazov Konstantin , Fetzer Jasmin
Published: September 2024

Abstract. At treeline, plant life forms and species are abruptly changing from low stature plants in the tundra to trees in forests. Our study assesses how this shift in vegetation affects the quality and elemental composition of the litter layer and consequently, the microbial processing and nutrient release during decomposition. We sampled litter layers along elevation gradients across conifer and broadleaf dominated treelines in the Russian subarctic Khibiny mountains and hemiboreal South Urals. In incubation experiments using microlysimeters at 5 and 15 °C, we measured carbon (C) mineralization and the release of inorganic nitrogen (N) and phosphorus (P), reflecting net N and P mineralization. We also measured releases of dissolved organic C and N and analyzed the functioning and stoichiometry of microbial biomass. Results showed that the chemical characteristics of the litter layer fundamentally changed across both treeline ecotones. On average, C:N and C:P ratios decreased by 56 and 65 % from tundra to forest, whereas lignin contents showed a 110 %-increase. The consistent decrease in C:N:P ratios in the litter layer from tundra to forest was paralleled by pronounced increases in net N and P mineralization from the tundra towards the low elevation forest in both treeline ecotones. In contrast to net nutrient mineralization, C mineralization and the release of dissolved organic C and N did not change across both treeline ecotones. In microbial biomass colonizing the litter layer, C:N and C:P ratios decreased on average by 26 and 74 % from tundra towards forest. The metabolic quotient (qCO2) correlated positively with C:N and C:P ratios of the litter layer. In support, the substrate-use efficiency estimated by the microbial use of 13C labelled glucose-6-phosphate increased from the tundra to the forest with decreasing C:N:P ratios. In contrast, potential activity of a range of C-N-P-acquiring extracellular enzymes showed no consistent pattern. Overall, our results give evidence that the vegetation shift from tundra to forest is associated with an abrupt increase in net N and P mineralization in the litter layer, accelerating nutrient cycling and increasing N and P availability. Experimental warming by 10 °C was less important for net N and P mineralization than litter composition. This implies that indirect effects of climatic warming through changes in plant community composition with treeline advances seem to be more important for soil N and P cycling than direct temperature effects.
Urban geography in crisis times: insights from a feminist project
Authors: Peake Linda , Katsikana Mantha , Adeniyi-Ogunyankin Grace , Datta Anindita , Basu Swagata , de Souza Karen , Ip Penn Tsz Ting , Marcus Joy , Ponce Carmen , Razavi Nasya S. , Smyth Araby , Yousuf Biftu
Published: September 2024

Abstract. In this short intervention addressing the impact of crises on geographical knowledge practices, we, members of GenUrb (a multi-sited, longitudinal, partnered urban research project), ask, “what counts as crisis?”, sketching out epistemological and methodological points about our project's engagement with this call. We query the adeptness of dominant Eurocentric epistemologies in addressing crises, adopting the work of Bedour Alagraa, who places crises firmly within a historical–geographical colonial framing that conceptualizes crises not through rupture but through continuation. We illustrate the utility of this epistemological framing of crisis, honing in on the everyday violence that women continually experience, with our research in the cities of Cochabamba, Delhi, Georgetown, Ibadan, Ramallah, and Shanghai, showing that one in every two women participants had experienced intimate partner violence. We further ask what crises mean for the methodologies we adopt, specifically concerning questions of the co-production of knowledge and methods.
Chempath 1.0: An open-source pathway analysis program for photochemical models
Authors: Garduno Ruiz Daniel , Goldblatt Colin , Ahm Anne-Sofie
Published: September 2024

Abstract. We describe the development of Chempath: an open-source pathway analysis program for photochemical models. This algorithm can help understand the results of complex photochemical models by identifying the most important reaction chains (pathways) for the production and destruction of a species of interest in a reaction system. The algorithm can also quantify the contribution of the pathways to the production and destruction of a species. We demonstrate how to apply Chempath to a one-dimensional photochemical model, using an example of a reaction system for Earth's present-day atmosphere. We validate that Chempath can identify well-known chemical mechanisms for O3 production and destruction in this model, suggesting that this algorithm can be applied to understand photochemical models of less well-known atmospheres, like past and exoplanet atmospheres.
Technical note: Monitoring discharge of mountain streams by retrieving image features with deep learning
Authors: Fang Chenqi , Yuan Genyu , Zheng Ziying , Zhong Qirui , Duan Kai
Published: September 2024

Abstract. Traditional discharge monitoring usually relies on measuring flow velocity and cross-section area with various velocimeters or remote-sensing approaches. However, the topography of mountain streams in remote sites largely hinders the applicability of velocity–area methods. Here, we present a method to continuously monitor mountain stream discharge using a low-cost commercial camera and deep learning algorithm. A procedure of automated image categorization and discharge classification was developed to extract information on flow patterns and volumes from high-frequency red–green–blue (RGB) images with deep convolutional neural networks (CNNs). The method was tested at a small, steep, natural stream reach in southern China. Reference discharge data were acquired from a V-shaped weir and ultrasonic flowmeter installed a few meters downstream of the camera system. Results show that the discharge-relevant stream features implicitly embedded in RGB information can be effectively recognized and retrieved by CNN to achieve satisfactory performance in discharge measurement. Coupling between CNNs and traditional machine learning models (e.g., support vector machine and random forest) can potentially synthesize individual models' diverse merits and improve generalization performance. Besides, proper image pre-processing and categorization are critical for enhancing the robustness and applicability of the method under environmental disturbances (e.g., weather and vegetation on river banks). Our study highlights the usefulness of deep learning in analyzing complex flow images and tracking flow changes over time, which provides a reliable and flexible alternative apparatus for continuous discharge monitoring of rocky mountain streams.
The connection between North Atlantic storm track regimes and eastern Mediterranean cyclonic activity
Authors: Sandler Dor , Saaroni Hadas , Ziv Baruch , Tamarin-Brodsky Talia , Harnik Nili
Published: September 2024

Abstract. A unique chain connects the flow over the North Atlantic and the development of cyclones within the Mediterranean basin. One typical mechanism includes several successive processes: upper-level flow perturbations upstream cause Rossby wave breaking (RWB) events along the jet stream, which in turn develop into potential vorticity streamers. These streamers reach the Mediterranean, and through increased baroclinicity they enhance cyclonic activity in the region. Using European Centre for Medium-Range Weather Forecasts (ECMWF) reanalysis v5 (ERA5) data and rain gauge measurements, we provide a systematic analysis connecting wintertime North Atlantic storm track regimes and eastern Mediterranean cyclones and rainfall. To do so, we use different detection algorithms for each element in the chain (RWBs, streamers and cyclones). A cluster analysis of upper-tropospheric eddy kinetic energy reveals a favorable configuration of the storm track where North Atlantic storms are able to propagate farther northeast. This results in upper-level potential vorticity streamers forming more eastward alongside above-average precipitation over the Levant. Meanwhile, other latitudinal positions of the storm track (southward or northward) were found to hinder cyclonic activity in the region and reduce rainfall there. The intense rainy winter of 1991–1992 is brought as a test case to exemplify this mechanism in its extreme. We show that the rain-enhancing storm track regime was prominent throughout most of this season, alongside frequent streamers in the eastern Mediterranean.
Corpus Linguistic Approach for Onomastics in Drama
Authors: Sfeir Maya
Published: September 2024

Proper names and naming are an integral component of dramatic texts. However, to date, scant and fragmented scholarly attention has been given to the connection between proper names and key dramatic elements—namely, stage directions, characterization, and plot progression. This paper adopts corpus linguistics as a method to show how a corpus linguistic approach to onomastics in drama can, on the one hand, provide analysts with a scoping overview of names and naming in plays, and, on the other hand, offer a richer insight into core dramatic elements. Using as a case study Edward Childs Carpenter’s play The Cinderella-Man (1915), it argues that corpus analysis and visualization techniques such as keyword analysis, frequency analysis, concordance analysis, collocation analysis, and dispersion plot analysis can enrich the study of names and naming in drama. The paper contributes to and extends recent research that has called for the incorporation of corpus linguistic approaches in onomastics research.
Note on the ‘toponym’ R Package
Authors: Chevallier Lennart , Wichmann Søren
Published: September 2024

In this note, we describe how to install and use the ‘toponym’ R package, which is designed for mapping and manipulating toponymic data from the GeoNames database. This introduction will allow even unexperienced users of R to efficiently produce maps and perform simple analyses.
Book Review
Authors: DeVinne Christine
Published: September 2024

Names of New York: Discovering the City’s Past, Present, and Future Through Its Place-Names. By Joshua Jelly-Shapiro. New York: Penguin Random House. 2021. Pp. 243. (Hardback) $22.00. ISBN 13: 978-1-5247-4892.
Morphometric analysis of the frontal horns of the lateral ventricles using normal computed tomographic images
Authors:   Department of Human Anatomy and Cell Biology, Delta State University, Abraka, Nigeria, Ominde Beryl S. , Ogbolu Emmanuel C. ,   Department of Human Anatomy and Cell Biology, Delta State University, Abraka, Nigeria, Ikubor Joyce E. ,   Department of Radiology, Delta State University Teaching Hospital, Oghara, Nigeria, Omoro Orovwoghene F. ,   Department of Human Anatomy and Cell Biology, Delta State University, Abraka, Nigeria, Igbigbi Patrick S. ,   Department of Human Anatomy and Cell Biology, Delta State University, Abraka, Nigeria
Published: September 2024

The ventricular system is altered by the normal aging process and various pathological conditions such as Alzheimer’s, schizophrenia, hydrocephalus, and tumors. This study aimed at establishing the normal baseline data regarding the dimensions of the frontal horns of the lateral ventricles in adults Nigerians. This retrospective observational study evaluated CT brain images stored in a Radiology unit in Delta State, Nigeria. Ethical clearance was sought from the Hospital’s ethics board. Images of 202 patients, aged 18 years and above, were included. Measurements of frontal horn length and width were conducted using a standardized digital caliper approach. The data were analyzed based on gender and age groups, employing statistical methods such as t-tests and Pearson correlation. A p-value of < 0.05 in the inferential statistics was deemed statistically significant. The length of the bilateral frontal horns and distance between their tips were significantly higher in males than in females (p<0.05). The left frontal horn length was consistently larger than the right. Both lengths and widths exhibited significant variations across age groups and had a positive correlation with age (p<0.05). The study provides standard reference values for clinicians in the study center to consider during neuroimaging and diagnostic assessments. The gender-, age- and side-related findings enhance the understanding of the normal anatomical diversity, which has crucial clinical implications.
Impacts of Phyllanthus niruri extract on biomarker levels, macrophage count, and lesion area in an endometriotic rat model
Authors: Wulandari Eka T. , Soetrisno Soetrisno , Purwanto Bambang , Reviono Reviono , Wasita Brian , Laqif Abdurrahman
Published: September 2024

Endometriosis is a gynecological disorder characterized by chronic inflammation, anatomical changes, prolonged pain, and infertility. On the other hand, Phyllanthus niruri is recognized for its pharmacological effects, which might be beneficial in managing endometriosis. The aim of the study was to investigate the pharmacological effects of P. niruri as a potential therapy for endometriosis by using an animal model. An experimental laboratory study with randomized, controlled trial, pre-test, and post-test design using 40 female Wistar rats (Rattus norvegicus) was conducted at the Integrated Research and Testing Laboratory (LPPT) of Universitas Gadjah Mada, Yogyakarta, Indonesia, from February to June 2023. Endometriosis was induced in female Wistar rats by suturing a 0.5 cm2 flap from the uterine horn to the peritoneal cavity. Changes in serum interleukin 1β (IL-1β), malondialdehyde (MDA), and matrix metalloproteinase 9 (MMP-9), before and after the treatment, were analyzed using enzyme-linked immunosorbent assay. Hematoxylin and eosin (HE) staining were used to evaluate lesion size and macrophage quantity. The results suggested that the P. niruri extract with a dose of 196 mg/200 g body weight (BW) could significantly attenuate serum IL-1β (p=0.004), MMP-9 (p=0.021), and MDA (p=0.021). Rats receiving the P. niruri extract (196 mg/200 g BW) had significantly higher macrophage counts (p=0.003), but similar lesion area (p=0.093) as compared with the negative control. In conclusion, P. niruri demonstrated promising therapeutical effects on endometriosis by modulating IL-1β, MDA, and MMP-9 levels, although the effect was not pronounced on macrophage counts and lesion area.
Transformasi Ekonomi dan Sosial Melalui Konveksi Pakaian: Keberhasilan Kelompok Usaha Bersama (KUB) Rumah Jahit Lestari (RJL) dalam Implementasi Kewirausahaan Sosial dengan Peran PT Pertamina Hulu Rokan WK Rokan - Wilayah Operasi Bekasap Rokan
Authors:   PT Pertamina Hulu Rokan WK Rokan – Wilayah Operasi Bekasap Rokan, Priawansyah Priawansyah , Azizah Zara ,   PT Pertamina Hulu Rokan WK Rokan – Wilayah Operasi Bekasap Rokan, Harahap Reiki Nauli ,   Universitas Tanjungpura
Published: September 2024

Usaha Mikro, Kecil, dan Menengah (UMKM) sangat penting bagi masyarakat untuk memenuhi kebutuhan sehari-hari dan mendorong pertumbuhan ekonomi lokal. Namun, Pandemi COVID-19, keterbatasan inovasi produk, kapasitas produksi, dan penjualan telah menyebabkan stagnasi pendapatan bagi pelaku UMKM di beberapa kabupaten di Propinsi Riau seperti Bengkalis, Siak, Rokan Hilir, Kampar, Dumai, dan Pekanbaru. Untuk mengatasi hal ini, PT Pertamina Hulu Rokan WK Rokan - Wilayah Operasi Bekasap Rokan menjalin kemitraan dengan Politeknik Negeri Bengkalis (Polbeng) untuk meningkatkan kapasitas dan kemandirian pelaku usaha kecil dengan melakukan pendampingan dan pelatihan dalam merespon pasar sekaligus pengembangannya. Program Pemberdayaan Ekonomi Pemuda dan Perempuan - Kelompok Usaha Bersama (KUB) Rumah Jahit Lestari (RJL) dalam kemitraan itu berfokus pada KUB-RJL di Desa Tambusai Batang Dui, Kecamatan Mandau, Kabupaten Bengkalis. Sejak tahun 2022, Rumah Jahit tersebut telah menciptakan peluang usaha baru melalui bisnis konveksi pakaian, yang memproduksi pakaian kantor, seragam sekolah, dan Flame Resistant Clothing (FRC) untuk industri Migas. Saat ini, KUB-RJL memiliki 60 anggota, termasuk remaja putus sekolah, lansia, wanita, dan penyandang disabilitas. Manfaat program ini telah meluas hingga Desa Bangko Permata dan Bangko Bakti Kecamatan Bangko Pusako, Kabupaten Rokan Hilir, melalui kerjasama dengan BUMDes. Program ini merupakan implementasi dari inisiatif Creating Shared Value (CSV) yang tidak hanya mendukung keberlangsungan bisnis perusahaan tetapi juga menciptakan nilai ekonomi dan sosial bagi masyarakat sekitar. Tulisan ini membahas pentingnya pendampingan dan kemitraan dalam meningkatkan kesejahteraan ekonomi dan sosial melalui kemitraan strategis dan inisiatif peningkatan kapasitas
Optimización de Sistemas Fotovoltaicos para la Iluminación de Edificios Administrativos: El Caso de Villa María del Triunfo
Authors: Mamani Pachari Javier Jesús , Sanchez Ayte Jorge Augusto
Published: September 2024

El presente articulo aborda el diseño y cálculo de un sistema fotovoltaico Off Grid destinado a la iluminación de un edificio administrativo en el Complejo Deportivo Andrés Avelino Cáceres, ubicado en Villa María del Triunfo, Lima. Se detalla el proceso de selección de equipos y cálculo de cargas, iniciando con la identificación de cargas en equipos de iluminación y procediendo al dimensionamiento de los principales equipos basándose en fórmulas y catálogos de fabricantes. Se seleccionaron paneles monocristalinos y otros componentes para cumplir con la demanda energética, validando los cálculos con el software PVSYST 7.4. Este diseño busca reducir la dependencia del sistema interconectado nacional, disminuir emisiones de gases de efecto invernadero y mejorar la imagen institucional mediante la implementación de energías renovables
Students’ Anxiety in Learning German: Types, Levels, Effects and Strategies
Authors: Susianti Hartanti Woro
Published: September 2024

Foreign language anxiety is a psychological factor that significantly influences the process of acquiring a foreign language. This anxiety often manifests as feelings of incompetence triggered by concerns about being monitored, judged, or compared to others. This study on the anxiety experienced by students learning German at Bali Tourism Polytechnic (BiTP) employs a qualitative approach using case study and phenomenological methods. Data were collected through in-depth interviews, participatory classroom observations, and related documents. The data were analyzed using thematic analysis methods. The research findings indicate that students experience various types of anxiety, such as state anxiety, situation-specific anxiety, anxiety in testing situations, facilitating anxiety, and debilitating anxiety. The levels of anxiety experienced by the students were mostly low to moderate. Foreign language anxiety has negative impacts, such as decreased performance, avoidance of language-use situations, and reduced motivation. However, anxiety can also have positive effects when managed well, such as serving as motivation to study harder. To minimize anxiety, instructors can provide positive feedback, prepare adequate materials and exercises, use collaborative and supportive teaching methods, and encourage students to focus on the learning process and their personal development.
Motivation of Domestic Tourists Visiting Bongkasa Pertiwi Village, Bali, Indonesia
Authors: Andreyana I Gede Eka
Published: September 2024

This research, employing a quantitative descriptive approach, aims to understand the motivation of domestic tourists visiting Bongkasa Pertiwi Village, viewed from the dimensions of push and pull factors. Data were collected through questionnaires distributed to 100 respondents and analyzed using confirmatory factor analysis. The results of the study indicate that among the nine push factor dimensions and six pull factors investigated, each has dominant factors influencing domestic tourists to visit Bongkasa Pertiwi Village. The dominant push factors are: 1) wanting to enjoy a different atmosphere and environment, 2) wanting to enjoy the journey, 3) wanting to enjoy tourist attractions for pleasure, 4) wanting to spend time with friends or family, 5) wanting to impress family and friends, 6) wanting to meet and interact with new people, 7) wanting to learn about new cultures, 8) wanting to improve skills and self-evaluate, and 9) wanting to visit a place they have long wanted to visit. Meanwhile, the six dominant pull factors for tourists are: 1) affordable rental facility prices, 2) interesting historical sites, 3) good weather and climate, 4) strategic location, 5) comprehensive tourism facilities, and 6) safety from criminal acts.
The Impact of Non-Muscle-Invasive Recurrence of Upper Tract Urothelial Carcinoma on The Survival of Patients After Radical Nephroureterectomy
Authors: Orlov A. S. , Mager V. O. , Shcheglova V. P. , Kovalenko D. A. , Sorochkin D. A. , Ivanov S. E.
Published: September 2024

Introduction. After radical nephroureterectomy for the upper tract urothelial carcinoma (UTUC), 15–50 % of patients have a relapse in the bladder. Non-muscle invasive relapse in the bladder (NMIR) occurs in 80–90 % of all types of bladder relapses.

The purpose of the study is to evaluate the effect of NMIR on patient survival after RNUE, and study the characteristics of the primary tumor and its effect on the occurrence of NMIR.

Materials and methods. 157 patients underwent surgical treatment for UTUC during the period from 2011 to 2021. Overall (OS), progressive free (PFS), and cancer-specific (CSS) survival in patients with a relapse in the bladder was analyzed. Cox regression analysis was used to estimate the risk of NMIR.

Results. NMIR was observed in 32 patients (20.4 %). 5‑year OS, PFS and CSS of patients with NMIR was higher than in the group of patients without NMIR and amounted to 92.4 %, 96.6 %, 93.4 % versus 61.4 %, 74.9 %, 68.9 % respectively. When comparing the clinical and pathomorphological characteristics, it was found that the primary tumor G3, locally advanced tumor are significantly less common in the NMIRC group, while concomitant bladder cancer, simultaneous lesion of the renal pelvis and ureter, as well as non-muscle-invasive cancer are significantly more common in the NMIRC group. According to the multivariate regression analysis, the risk of NMIRC increases by 2 times with simultaneous tumor lesion of the renal pelvis and ureter (HR — 2.93; 95 % CI — 1.43–7.13; p = 0.005) and concomitant bladder cancer (HR — 2.89; 95 % CI — 1.01–6.11; p = 0.035).

Conclusion. Significantly better survival rates were found for patients with UTUC in the presence of NMIR. Patients with NMIR are significantly less common to have aggressive forms of the primary tumor and a locally advanced disease.
Long-Term Results of Treatment of Patients with Stage IV Malignant Melanoma in the Sverdlovsk Region
Authors: Petkau V. V. , Beloglazova E. P. , Sokolova A. V.
Published: September 2024

Introduction. Despite advances in early diagnosis, in 5–10 % of cases, melanoma is detected at stage IV. In recent years, there have been breakthroughs in the drug treatment of metastatic melanoma. Against this background, modern data on overall survival (OS) of this group of patients in Russia are relevant, but rarely published.

Objective — to assess the OS of patients with stage IV melanoma depending on the clinical and biological characteristics of the tumor and the treatment performed in real clinical practice.

Materials and methods. We retrospectively studied medical documentation in the Medofis medical information system and the regional information system ONKOR of 300 patients, residents of the Sverdlovsk region, with the first stage IV of skin melanoma, first identified from 1 January 2014 to 1 January 2023. Observation was carried out until 1 February 2024.

Results. 61.3 % of patients received antitumor drug therapy. Analysis for the BRAF mutation was performed in 46.3 % of the total number of patients (75.5 % of those who received specialized treatment). A mutation in the BRAF gene was detected in 52.5 % of cases. The 1‑year OS of patients with malignant melanoma of the skin was 47.0 %, the 3‑year OS was 27.3 %. Survival rates for patients receiving targeted or immune therapy were higher. From 2014 to 2023, the proportion of patients receiving targeted therapy or checkpoint inhibitor therapy increased from 11.5 % to 69.7 %.

Conclusions. There was an increase in median OS, 1‑year and 3‑year OS depending on the time of diagnosis of the disease, specialized treatment, number of lines of drug therapy, use of targeted drugs, checkpoint inhibitors.
Evaluation of Ultrasound and Intraoperative Histological Methods in the Diagnosis of Sentinel Lymph Node Metastases in Various Biological Subtypes of Breast Cancer
Authors: Magdalyanova M. I. , Popova A. Y. , Zornikova O. S. , Kazantseva N. V. , Dorofeev A. V. , Beloglazova E. P. , Shevchenko S. A. , Zornikov D. L. , Perfilyev V. D.
Published: September 2024

Introduction. Determination of biological subtypes of breast cancer after clinical and instrumental examination methods is a routine practice to determine individualized treatment tactics, to clarify the prognosis of the disease, and to prevent overtreatment. Polymorphism of breast cancer manifestations is associated with heterogeneity of biological subtypes of breast tumors. Identification of metastatic axillary lymph nodes has clinical and prognostic significance.

Objective — to assess the significance of ultrasound examination of axillary lymph nodes in patients with various biological subtypes of breast cancer in real clinical practice.

Materials and methods. The study included 895 patients aged from 28.8 to 91.8 years with a verified diagnosis of breast cancer, observed at the Sverdlovsk Regional Oncology Center in 2022. All patients underwent clinical, ultrasound evaluation of axillary lymph nodes, histological verification of the tumor at the preoperative stage, as well as routine and intraoperative histological examination of the sentinel axillary lymph nodes. Statistical processing and data visualization were performed using R version 4.3.2 (build 2023-10-31).

Results. In our sample of patients, TNR was less associated with metastasis to axillary LU compared with luminal cancers. There was no effect of different molecular subtypes on the preoperative ultrasound and intraoperative histologic examination parameters.

Conclusions. Among our patients TNC was less associated with metastasis to axillary lymph nodes compared to luminal cancers. There was no effect of different molecular subtypes on the performance of ultrasound and intraoperative histological methods of examination.
Radiomics in the Radiation Diagnosis of Biological Subtypes of Breast Cancer (Literature Review)
Authors: Popova A. Y. , Gazhonova V. E. , Kartashov M. V. , Shevchenko S. A. , Belova O. S.
Published: September 2024

Introduction. Breast cancer (BC) has a leading position among oncological diseases in women. Early diagnosis and search for predictors of malignant neoplasms using radiation imaging methods allows timely diagnosis and treatment, which improves the prognosis for BC. Most of the data obtained by radiological imaging is largely non-specific at the molecular level. Radiomics is engaged in solving these issues, which performs a comprehensive quantitative assessment of tumor phenotypes by extracting a large number of quantitative signs from medical images.

Purpose — systematization of modern scientific directions of radiomics in the radiation diagnosis of BC.

Methods. Comprehensive analysis of PubMed and eLibrary.ru electronic databases over the past 5 years.

Results. Based on the studied literature data, we identified the main promising scientific directions for the development of radiomics in the radiation diagnosis of BC: the study of the prevalence of BC, its risk factors, new screening approaches in the early diagnosis of BC; the search for specific markers and available visualization of signs of a certain molecular type of BC; the search for prognostic predictors and the study of the accuracy of the forecast based on the identified characteristics; identification of the possibilities of personalized therapy, assessment of the most effective treatment and modern management of cancer patients; expansion of the possibilities of radiomics in combination with other scientific fields.
Reconstruction of the Chest Wall During Extensive Resections. Literature Review. Own Experience
Authors: Rudenko M. S. , Kamenev R. O. , Gusev D. A. , Eliseeva A. P.
Published: September 2024

Tumors of the chest wall are a relatively rare disease in clinical practice. Most published studies of chest wall tumors are typically single-center, retrospective studies involving small numbers of patients. Thus, evidence for clinical findings regarding chest wall tumors is currently lacking. The article reviews the literature and highlights the epidemiology of chest wall tumors. The types of materials for reconstruction, the methods used for chest wall plastic surgery for extensive resections, and complications are described in detail. The authors presented their own experience in treating 42 patients who, for one reason or another, underwent resection of the bone structures of the breast. According to the etiology, the tumors were divided into: non-small cell lung cancer with invasions into the chest wall (9 patients, 21.4 %), invasion of breast cancer (2 patients, 4.8 %), sarcomas (chondrosarcomas, osteosarcomas, soft tissue sarcomas; 13 patients, 31 %), metastases of malignant tumors of various origins and localization (9 patients, 21.4 %), benign tumors (8 patients, 19 %), dysmoid tumor (1 patient, 2.4 %). 22 (52.3 %) patients underwent plastic surgery of the resulting defect. Of these, myoplasty, plastic surgery with a diaphragm, local tissues (8 patients, 36.4 %), alloplasty with a polypropylene mesh (6 patients, 27.3 %), alloplasty with a polymer plate (7 patients, 16.7 %). In 3 cases, alloplasty was supplemented by replacement of soft tissues with a thoracodorsal flap. The methods of plastic surgery and the materials used are described. In the postoperative period, the authors did not observe complications associated with paradoxical breathing.