bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrated knowledge-translation in occupational therapists working with high-risk infants in South Africa: An explorative qualitative inquiry
Authors: Dawood Ayesha , Govender Pragashnie , York Samantha J , Rencken Gina , Ogunlana Michael O
Published: September 2023

BACKGROUND: This qualitative study explored the knowledge to practice gaps of occupational therapists who have a vital role in neurodevelopmental supportive care for high-risk infants METHODS: Via purposive sampling, 17 therapists working in public health in South Africa were recruited to participate in virtual focus groups. Data were thematically analysed using a hybrid approach FINDINGS: Five themes emerged, which included (i) occupational therapy and neonatal care in the public health sector, (ii) knowledge acquisition and knowledge synthesis, (iii) knowledge translation and utilisation, (iv) contextual barriers and adaptation and (v) the ideal occupational therapist in the ideal neonatal setting. Facilitators, inhibitors, referrals, and interest in occupational therapy neonatal care were also highlighted CONCLUSIONS: Knowledge to practice gaps in occupational therapy include insufficient training, a decreased interest in neonatal care, staff shortages, multi-disciplinary team rotations and a reduced understanding of the professional role and scope of occupational therapy. Resources, training, and policy development appear to be necessary to inform a standard of care Implication for practice The role of the occupational therapist in supporting high risk infants is generally limited and remains somewhat unknown in current South African contexts. It is essential to identify knowledge-to-practice gaps for occupational therapists supporting high-risk infants in the public health sector for successful implementation of neurodevelopmental supportive care. By the exploration of practitioner opinions and insight through appreciating the role of the occupational therapist in managing high risk infants, contextually specific and relevant knowledge translation interventions may be developed and implemented which have implications for evidence-based practice and more successful outcomes in the high-risk infant.
Internal marketing and employees’ perception of organizational performance in the maritime organization: The mediator and moderator role of satisfaction and work experience
Authors:   Ordu University Fatsa, Ordu, Turkey, Şenbursa Nihan , Tehci Ali ,   Ordu University Fatsa, Ordu, Turkey
Published: September 2023

Purpose. This research aims to bring to light the relationship between organizational performance perceptions of the employees in the maritime sector, employee satisfaction and internal marketing. Study design. The data obtained through a questionnaire from 357 office workers in aTurkish ship-owner company were tested with the Structural Equation Model using SPSS 24.0 AMOS21.0 statistical package program. The large percentage of the study’s participants are men. However, it can be said that the distribution obtained in the research is in parallel with the ratio of female and male employees in the maritime business. Most of the employees work in the operations department of the company, followed by the management, marketing and logistics departments, respectively. Findings. As a result, it was determined that internal marketing has a positive effect on employees’ perception of organizational performance. In addition, job satisfaction has a mediating role in the effect of internal marketing on organizational performance of employees, also work experience has a moderating role in the impact of internal marketing on organizational performance of employees. Value of the results. In the future this study might be applied to sea farers or other maritime industry employees. Authors expect that this study will shed light on both researchers who study on similar subjects and organizations that would like to expand their horizon in terms of employee relations.
The relationship between alexithymia and counterproductive behaviors in the workplace
Authors:   Dogus University, Dogus University, Istanbul, Turkey, Ucok Dilek
Published: September 2023

Purpose. The concept of alexithymia which is expressed as individuals having difficulty defining, regulating, and expressing their emotions, is believed to be on the rise in organizational life. It is argued that it is not possible for employees who have difficulty defining their emotions to build positive relationships in the workplace. Therefore, this study aims to investigate whether alexithymia has an impact on counterproductive work behaviors. Study design. Data were collected through the convenience sampling method from 334 employees working in public and private sector organizations in Turkey. The mean age of the participants is 34.1 years, the mean seniority in the profession is seven years, and the mean seniority in their organizations is three years. The data was collected through asurvey form. The Counterproductive Work Behaviors Scale (CWB) and Toronto Alexithymia Scale (TAS-20) were used in the data collection tool. Findings. The study revealed that alexithymia has a significant contribution to counterproductive work behaviors. Moreover, it was found that alexithymia has a stronger contribution to organizational deviance (Cwb-O) than employee deviance (Cwb-P). As a result of the simple regression analysis carried out to determine to what extent the sub-dimension of alexithymia predicts counterproductive work behaviors in the workplace. “Having difficulty recognizingand verbalizing emotions” significantly predicted counterproductive work behaviors towards the organization (β = .65, t = 15.7, p = .00) and counterproductive work behaviors towards the employee (β = .42, t = 8.52, p = .00). Value of results. The findings of the study will provide a new perspective on counterproductive work behaviors in organizations and contribute to the industrial and organizational psychology literature as it is the first study in Turkey regarding the relationship between alexithymia and counterproductive work behaviors.
Vascular risk factors and carotid atheromatous disease in patients over 65 years of age
Authors: Sónia Mateus , Vanda Pós de Mina , Patrícia Coelho , Francisco Rodrigues , Irene Mendes
Published: September 2023

Introduction: Vascular risk factors are decisive in the evolution of atherosclerotic disease and the carotid and vertebral Doppler ultrasound allows monitoring its onset and progress. The measurement of arterial wall thickening allows the early diagnosis of the disease enhancing its treatment and control of vascular risk factors. Aim: Analysing the presence of atheromatous disease in individuals aged > 65 years and understanding its correlation with vascular risk factors. Materials and methods: This is a cross-sectional observational study, in individuals aged > 65 years and underwent carotid echoDoppler between January 1, 2012, and December 31, 2021. The intimal-media index was calculated, as was the presence of atheromatous plaques, their hemodynamic repercussion and vascular risk factors were recorded. Results: A sample of 5885 individuals was obtained with 41.8% female and 58.2% male. The mean age was 76.59 (± 6.69), with a range between 65 and 98 years. Arterial hypertension was the most prevalent 81.3%. There was a significant positive relationship between the intima-media index and age (p = 0.001). In the presence of plaques, male gender, arterial hypertension, diabetes, dyslipidemia, and smoking it presents a positive correlation. Conclusion: In this sample, non-modifiable vascular risk factors seem to be determinants in the presence of increased arterial wall thickness. In the presence of signs of a more advanced stage of atherosclerotic disease, modifiable vascular risk factors are decisive, corroborating the already-known importance of strict control over them for their treatment.
Korean Elderly’s Demand for Supplying Elderly-friendly Dosage Forms Easy to Swallow
Authors:   The Pharmaceutical Society Of Korea, Lee Eun Joo , Sohn Hyun Soon
Published: September 2023

As the population ages, it has become increasingly important to provide elderly-friendly dosage forms (EFDF) that are easy to take and promote medication adherence to achieve treatment goals. This cross-sectional questionnaire study, conducted during October to November 2021, aimed to investigate the demand for EFDF among elderly individuals aged 65 years or older. Of the 421 respondents, 81.9% were prescription drug users, 34.9% experienced difficulty swallowing pills, and 26.8% had previous experience of not taking medication due to swallowing problems. 64.1% of respondents agreed to necessity of EFDF easy to swallow than oral solid form, their preferred dosage forms were powder (19.7%) and liquid (57.7%). Furthermore, 51.8% showed willingness to pay additional cost for EFDF. The demand for EFDF was significantly higher in women, facility residents such as nursing homes, elderly living alone, and elderly had difficulties in swallowing and experiences of not taking pills. Considering the elderly themselves personal preferences and improvement of medication adherence, we suggest that pharmaceutical industry and government begin further discussion on EFDF more positively.
The Societal/economical Impact of Trastuzumab-deruxtecan in Patients with Human Epidermal Growth Factor Receptor2-positive Metastatic Breast Cancer
Authors:   The Pharmaceutical Society Of Korea, Choi Ahhyung , Ko Hwa Yeon , Hong Bin , Bae Ji-Hwan , Oh In-Sun , Park Sun-Kyeong , Park Yeon Hee , Shin Ju-Yong
Published: September 2023

In the recent DESTINY-Breast03 trial, trastuzumab deruxtecan (T-DXd) has shown significantly prolonged progression free survival (PFS) compared with trastuzumab emtansine (T-DM1) among human epidermal growth factor2- positive metastatic breast cancer (HER2+ MBC) patients. While there is clear evidence of the clinical benefits of T-DXd, evidence on societal effects that go beyond these clinical benefits is yet to be explored. Thus, we estimated the socioeconomic benefits of T-DXd compared to T-DM1 among HER2+ MBC patients. We first calculated the incremental health benefits that T-DXd generates compared to T-DM1 in terms of prolonged PFS. We then translated the incremental PFS into the time spent on paid work and unpaid work hours. Lastly, the overall societal impact of T-DXd was yielded by aggregating the potential gross domestic products that can be generated from both paid and unpaid work hours. We identified 2,212 patients who are eligible for the analyses. Overall, the prolonged PFS of T-DXd resulted in a socioeconomic benefit of approximately 260 billion KRW, which corresponded to 110 million KRW per patient. In conclusion, we observed considerable socioeconomic benefits that come along with the use of the novel drug, T-DXd, which will be helpful for healthcare policymakers in decision-making.
Real world tablet-splitting prescription status of enteric-coated tablets of diclofenac sodium and aspirin
Authors:   The Pharmaceutical Society Of Korea, Yun Seung Won , Chun Pusoon
Published: September 2023

This study aimed to investigate tablet-splitting prescription of enteric-coated tablets of diclofenac sodium and aspirin. We conducted a retrospective cross-sectional study using claims data collected by the Health Insurance Review and Assessment Service (HIRA) of Korea during 2016-2020. Of the 1,227,666 prescriptions of aspirin 100 mg enteric-coated tablet, 941 tablet-splitting prescriptions were identified, accounting for 0.1%. Of the 941 prescriptions, 41.7% (392) were prescribed for the elderly individuals aged 65 years. Of the 334 tablet-splitting cases with 15 or more consecutive days of prescription, 58.7% (196) were found in the elderly. Furthermore, 37.0% (37/100), 37.1% (13/35), and 40.4% (36/89) of cases with consecutive days of prescription of 31-60, 61-90 days, and more than 90 days, respectively, gastrointestinal disorders were found. Of the 53,868 prescriptions of diclofenac sodium 25 mg enteric-coated tablet, 2,248 tablet-splitting prescriptions were identified, accounting for 4.2%. Furthermore, of the 2,248 prescriptions, 53.0% (1,192) were prescribed for children under 5 years old, and 33.1% (744) were prescribed for children aged 5-9 years, respectively. We found that tablet-splitting prescription rate of diclofenac sodium 25 mg was high, especially in children. Gastrointestinal disorders were common in the tablet-splitting prescriptions of aspirin 100 mg, especially in the cases with 15 or more consecutive days of prescription.
Perceived Stress and Social Media Addiction: Mediating Role of Flow Experiences
Authors: KARABACAK ÇELİK Aynur , PEKER Adem
Published: September 2023

Social media addiction is a problem that has been emphasized in recent years and experienced by university students. Researchers have carried out many studies to clarify its antecedents and reduce this addiction. However, little is known about the positive effect of flow experiences in reducing social media addiction. In this context, the goal of this current research is to determine the mediator role of flow experiences in the relations between perceived stress and social media addiction. Participants comprised 542 university students (377 female and 165 male). The research used the Social Media Addiction Scale, the Perceived Stress Scale, and the Flow State Scale. Research results demonstrate that perceived stress and social media addiction have a statistically significant positive correlation, while flow experiences have a negative correlation. The findings also showed a bad correlation between social media addiction and experiences of flow. The mediation analysis results showed that flow experiences have a statistically significant mediating role in the relationships between perceived stress and social media addiction. Research findings underline that the positive effect of flow experiences is essential in reducing perceived stress’s impact on social media addiction.
The significance of the LIFEPLAN's Training and Equipping Programme on the spiritual and general well-being of farmworkers in the Christiana district in South Africa
Authors: Freeks Faizel
Published: September 2023

The main focus of this article is to determine the significance of the LIFEPLAN's programme by employing quantitative research such as questionnaires distributed to selected candidates. The participants were the farm workers (N=151) between 21 and 62 years (mean age=35.81, SD=10.407) who attended the LIFEPLAN's training and who forms part of the intervention programme. An exploratory, interpretive as well as descriptive quantitative contextual design was followed. The results from this quantitative pattern indicated that participants are convinced their life is on the right track after the LIFEPLAN's intervention. In conjunction with this belief, participants indicated that their life has gained a sense of direction or meaning due the LIFEPLAN's programme. Their spiritual well-being, for example, are enriched where 80% indicated that they have a personally meaningful relationship with God. According to participants this meaningful relationship contributes largely to their sense of well-being.
Területfejlesztési források felhasználása Baranya megyében
Authors: Pámer Zoltán , Finta István , Horeczki Réka , Pénzár Árpád , Dombi Péter
Published: September 2023

Baranya több szempontból is sajátos helyzetben lévő megye. Gazdasági szerkezete miatt a rendszerváltás átalakulása komolyan érintette, majd a délszláv háború és a külföldi tőkebefektetések – részben ebből következő – elmaradása mind hozzájárultak perifériára kerüléséhez, melyet tovább fokozott a kimaradás a 2008-as gazdasági válságot követő konjunktúra előnyeiből. A befektetések hiánya miatt az EU-források kiemelt szerepet játszanak a megye fejlődésében.
A tanulmány bevezető része Baranya rendszerváltás óta bejárt fejlődési pályáját vázolja fel, majd áttekinti a meghatározó közjogi-intézményi változásokat és bemutatja a megye fejlesztési dokumentumait. A vizsgált kérdések és alkalmazott módszerek részletezését követően az EU kohéziós politikája keretében allokált források felhasználását elemezzük. Összehasonlítjuk a 2007-2013 és a 2014-2020 közötti programozási időszak felhasznált és kifizetett forrásokra vonatkozó adatait, majd a 2014-2020 közötti Terület és Településfejlesztési Operatív Program megyei adatai alapján részletesen elemezzük a források prioritások szerinti megoszlását a járások fejlettsége, a települések jogállása, valamint településméret-kategóriák alapján. A zárófejezetben javaslatokat fogalmazunk meg a megyei fejlesztéspolitika területalapú jellegének továbbfejlesztésére vonatkozóan.
Vizsgálatunk legfontosabb megállapítása, hogy ugyan a korábbiakhoz képest országosan is csökkent a fejlettebb térségekbe és nagyobb településekre juttatott források mértéke 2014-2020 között, Baranyában a forrásfelhasználást illetően vegyes a kép. A komplex programmal fejlesztendő járások és a kistelepülések aránya elmarad a megye sajátosságai által indokolt mértéktől, így járási szinten nem érvényesül a koncentráció elve, az egyes önkormányzatok által megvalósított projektek pedig nem feltétlenül a helyi kihívásokra reagálnak, így nem járulnak hozzá a perifériák felzárkóztatásához.
Pécs és Baranya megye fejlődése a történetileg változó földrajzi periférián
Authors: Horeczki Réka , Hajdú Zoltán
Published: September 2023

Pécs kapcsolatrendszere már a római időszakban is mikro-, mezo- és makroterületi vonatkozásokat hordozott. A város fejlődése beilleszkedett a mindenkori földrajzi környezetébe, a hatalmi-területi, állami, közigazgatási rendszerbe. A város földrajzi pozíciója korszakonként változott a hatalmi-államterületi átrendeződések következtében, már a magyar honfoglalás előtt is földrajzi-topográfiai periféria volt az éppen aktuális befogadó államában. Az első jelentős regionális szerepkörű intézmény létrejötte Pécsett királyi döntés eredménye volt, amely a török megszállás időszakát leszámítva folyamatosan működött. Baranya vármegye határmegyeként jött létre, lényegi szerepe volt a korai időszakban az ország déli határainak védelmében. Pécs és Baranya a mindenkori országterület déli részén helyezkedett el, periféria-adottsága objektivizálódott, s ez korántsem jelentett mindenkor hátrányt.

A tanulmány egy áttekintő történeti földrajzi bevezetés után az 1945-öt követő folyamatokat részletezi érdemben, hiszen ez a periféria-centrum a kiépülő államszocialista politikai berendezkedés miatt széles lehetőségeket kapott a település- és területfejlesztés folyamatában. A periféria-nagyvárosokkal, Budapest nevesített, tervezett ellenpólusaival, köztük Péccsel, szinte folyamatosan számolt a szak- és nagypolitika egyaránt. A történelmileg objektív országon belüli periféria-helyzet megjelenítése mellett hangsúlyt kap a város megyén belüli elhelyezkedése. A megyében topográfiai elhelyezkedésénél fogva (szinte a megye középpontjában fekszik) mindenkor, minden tekintetben központ volt.
The Status of the Treasurers in the Self-Government of Attorneys-at-Law
Authors: Kępa Monika
Published: September 2023

The professional self-government of attorneys-at-law is one of the functional self-governments established by the Constitution of the Republic of Poland, gathering persons practicing the profession of public trust. The Act on Attorneys-at-Law defines the tasks of this self-government and its internal structure. One of the statutorily distinguished functions in the structure of the self-government are the treasurers of the District Chamber of Attorneys-at-Law and the National Board of Attorneys-at-Law. They are members of the executive bodies of the councils at both levels of self-government units. Apart from the placement of treasurers in executive bodies and the general indication that they are elected by the relevant councils, the Act on Attorneys-at-Law does not explicitly contain any further regulations concerning them. The method of election and the competencies of treasurers are not specified in the Act on Attorneys-at-Law, but in intra-governmental acts issued by authorized bodies of the self-government. Overall, these competencies relate to the financial management carried out by the councils at both levels of self-government. This is an extremely important issue, as it provides the material basis for carrying out the statutory tasks of the self-government that comprise their constitutional functions. Letting the self-government normalize the issues that comprise the status of treasurers indicates the legislature’s belief in its ability to self-regulate. This corresponds to the essence of self-government and the principle of decentralization and independent performance of tasks by this self-government, including those of a public nature.
Res iudicata pro veritate accipitur in the Roman Civil Procedure
Authors: Stankiewicz Sebastian
Published: September 2023

The article attempts to analyze the meaning of the principle of res iudicata pro veritate accipitur in the Roman civil procedure. According to Roman law, once a final judgment was handed down in a lawsuit, it was considered to be truthful and this correspondence was supported by a legal presumption. The truth could correspond to reality (material truth) or emerge from the evidence gathered in the course of a legal case (formal truth). The purpose of the court’s activity in a civil procedure is to find the truth and, consequently, to render a fair court judgment.
Limits of Acceptable Economic Risk Determined by the Business Judgment Rule in the Light of the Assessment of the Elements of the Crime of Mismanagement
Authors: Świeca Karolina
Published: September 2023

This study is a presentation of the business judgment rule, which takes into account acting within the framework of legitimate economic risk as one of the prerequisites for the possibility of excluding legal liability for damage to a capital company. It is also worth noting that this rule is presented as a reference point in assessing the elements of the crime of mismanagement.
An Economy of Distraction: Ray Bradbury’s Vision of Technology in the Modern Age
Authors: Giraud Theodore
Published: September 2023

This article examines the role of technology in Ray Bradbury’s Fahrenheit 451 and a selection of his short stories (including “The Murderer” and “The Pedestrian”) with an emphasis on Bradbury’s views on overreliance on technology. Bradbury’s views on technology are complex and multifaceted, and his works explore the philosophical questions raised by a dependence on an increasingly technological world. Bradbury’s works caution against the dangerous repercussions of overuse of technology and the way in which individuals are often manipulated by it. The article examines the application of Bradbury’s ideas in the modern world and his views on technology’s effect on literacy and attention span, exploring Bradbury’s views on individual autonomy, and common themes within his work including dystopia, paranoia, and technological overreach. The article also examines Bradbury’s interviews and modern critical evaluations of the themes discussed, identifying commonalities within those themes. It seeks to evaluate the modern application of the ideas and themes discussed in Bradbury’s stories, and how those themes have evolved and continue to be relevant as technology progresses.
Development of Vehicle Detection and Counting Systems with UAV Cameras: Deep Learning and Darknet Algorithms
Authors: Rangkuti Abdul Haris , Athala Varyl Hasbi , Indallah Farrel Haridhi
Published: September 2023

This study focuses on identifying and detecting several types of vehicles, with each vehicle’s position depicted by drone technology or an Unmanned Aerial Vehicle (UAV) camera. The vehicle’s position is captured from a height of 350 to 400 meters above the ground. This study aims to identify the class of vehicles that travel on the highway. The experiment employs several convolutional neural network models, including YOLOv4, YOLOv3, YOLOv7, DenseNet201-YOLOv3, and CSResNext50-Panet-SPP, to identify this type of vehicle. Meanwhile, the Darknet algorithm aids the training process by making it easier to identify the type of vehicle depicted in MP4 movies. Several other Convolution Neural Network (CNN) model experiments were conducted in this study, but due to hardware limitations, only these 5 CNN models could produce an optimal accuracy of up to 70%. Following several experiments, the CSResNext50-Panet-SPP model produced the highest accuracy while detecting 100% of video data using UAV technology, including the volume of vehicles detected while crossing the road. Other CNN models produced high accuracy values, such as DenseNet201- YOLOv3 and YOLOv4 models, which can detect up to 98% to 99% of the time. This research can improve its capabilities by detecting other classes that are affordable by UAV technology but require hardware and peripheral technology to support the training process.
Systematic Configuration for Hyperparameters Optimization in Transferring of CNN Model to Disaster Events Classification from UAV Images
Authors: Bunrit Supaporn , Kerdprasop V Nittaya , Kerdprasop Kittisak
Published: September 2023

Deep learning and computer vision-based approaches incorporated with the evolution of the relevant technologies of Unmanned Aerial Vehicles (UAVs) and drones have significantly motivated the advancements of disaster management applications. This research studied a classification method for disaster event identification from UAV images that is suitable for disaster monitoring. A Convolution Neural Network (CNN) of GoogleNet models that were pretrained from ImageNet and Place365 datasets was explored to find the appropriate one for fine-tuning to classify the disaster events. In order to get the optimal performance, a systematic configuration for searching the hyperparameters in fine-tuning the CNN model was proposed. The top three hyperparameters that affect the performance, which are the initial learning rate, the number of epochs, and the minibatch size, were systematically set and tuned for each configuration. The proposed approach consists of five stages, during which three types of trials were used to monitor different sets of the hyperparameters. The experimental result revealed that by applying the proposed approach the model performance can increase up to 5%. The optimal performance achieved was 98.77 percent accuracy. For UAV/drone applications, where a small onboard model is preferred, GoogleNet that is quite small in model size and has a good structure for further fine tuning is suitable to deploy.
Solar Radiation and Weather Analysis of Meteorological Satellite Data by Tensor Decomposition
Authors: Watanabe N. , Ishida A. , Murakami J. , Yamamoto N.
Published: September 2023

In this study, the data obtained from meteorological satellites were analyzed using tensor decomposition. The data used in this paper are meteorological image data observed by the Himawari-8 satellite and solar radiation data generated from Himawari Standard Data. First, we applied Higher-Order Singular Value Decomposition (HOSVD), a type of tensor decomposition, to the original image data and analyzed the features of the data, called the core tensor, obtained from the decomposition. As a result, it was found that the maximum value of the core tensor element is related to the cloud cover in the observed area. We then applied Multidimensional Principal Component Analysis (MPCA), an extension of principal component analysis computed using HOSVD, to the solar radiation data and analyzed the Principal Components (PC) obtained from MPCA. We also found that the PC with the highest contribution rate is related to the solar radiation in the entire observation area. The resulting PC score was compared to actual weather data. From the result, it was confirmed that the temporal transition of the amount of solar radiation in this area can be expressed almost correctly by using the PC score.
Web-Based Application for Malaria Parasite Detection Using Thin-Blood Smear Images
Authors: Swastika Windra , Pradana Benedictus J. , Widodo Romy B. , Sitepu Rehmadanta , Putra Gregorius G.
Published: September 2023

Malaria is an infectious disease caused by the Plasmodium parasite. In 2019, there were 229 million cases of malaria with a death toll of 400.900. Malaria cases increased in 2020 to 241 million people with the death toll reaching 627,000. Malaria diagnosis which is carried out by observing the patient’s blood sample requires experts and if it is not done correctly, misdiagnosis can occur. Deep Learning can be used to help diagnose Malaria by classifying thin blood smear images. In this study, transfer learning techniques were used on the Convolutional Neural Network to speed up the model training process and get high accuracy. The architecture used for Transfer Learning is EfficientNetB0. The training model is embedded in a pythonbased web application which is then deployed on the Google App Engine platform. This is done so that it can be used by experts to help diagnose. The training model has a training accuracy of 0.9664, a training loss of 0.0937, a validation accuracy of 0.9734, and a validation loss of 0.0816. Prediction results on test data have an accuracy of 96.8% and an F1- score value of 0.968.
Chemopreventive Potential of Phytoestrogens on Hormone-Sensitive Cancer - An Updated Review
Authors: Subramani S.Priyadharshini , Selvaraj Jubie , Natarajan Jawahar
Published: September 2023

Hormone-dependent cancers contribute to the majority of cancer deaths in women. Treatment options for hormonal cancer such as breast, endometrial, prostate, and ovarian cancer aim at inhibiting key signalling pathways and hormones responsible for cell proliferation. Hormonal therapies in the long run cause musculoskeletal disorders, Disease reoccurrence, and drug resistance. There is a need for new alternative therapies to prevent and treat hormonal carcinomas. Phytoestrogens, a naturally occurring polyphenol have potent effects on hormonal cancers due to their estrogenic effects. Evidence suggests that phytoestrogens exert their apoptotic potential by interfering with steroidogenesis, gene expressions, and down-regulation of Protein Tyrosine Kinases, Matrix Metalloproteinases. They also act as topo-poisons. This review explains the key mechanisms of phytoestrogens in inhibiting cell proliferation in hormonal cancers by evidence from recent clinical studies, meta-analyses, and cohort study reports. Phytoestrogens have multi-target potential with both preventive and treatment properties on cancer cell lines. Combination therapies with phytoestrogens are more beneficial in controlling cell progression. Hence further research is required to explore their epigenetic properties on tumour suppressor genes which stay an important target in cancer research.
Charcot Spine Arthropathy (CSA)- a Rare Case Report
Authors: Singh Mahendra , Bharwani Nandlal , Ranjan Navendu , Bhati Mahesh
Published: September 2023

Charcot Spine Arthropathy (CSA) is a form of degenerative disease affecting vertebra of lumbar and thoraco-lumbar region. It is commonly seen after injury to the spinal cord or in patients with traumatic paraplegia. It was first described by Kronig in 1884. Case Report- A 35year old male patient presented to our outpatient clinic with complaint of difficulty in changing his position while sitting, lying down, and sitting on a wheel chair. In 2014, he had sustained injury to his spinal cord with bowel and bladder involvement with ASIA-A grade neurology for which long segment fixation was performed from D7-D10 level and the patient was wheel chair bound after surgery. In the present case scenario, the patient was managed conservatively with bed rest, immobilization and medications for pain relief as stated in the existing literature. Conclusion- CSA is a disease of surgical origin commonly seen in patients with spinal cord injury in the past. Although surgery in the form of circumferential arthrodesis is the treatment of choice in most of cases, it is reserved for cases with instability, as it is associated with complications like infections and hardware failure.
Cultivating Progress-The Crucial Link between Seed Selection and Agricultural Transformation in India
Authors: Kumar Pathak Madhwendra , Srivastava R.P. , Lohar Deepak
Published: September 2023

This review article, titled "Cultivating Progress: The Crucial Link Between Seed Selection and Agricultural Transformation in India," intricately examines the pivotal role that seed selection plays in shaping India's agricultural landscape. Through an exploration of seed diversity, indigenous knowledge, and the Green Revolution, it elucidates how the right choice of seeds has driven innovation, sustainability, and empowerment in Indian farming. The review underscores the importance of climate-resilient seeds, equitable access, and the synergy of biotechnology and genetic diversity conservation. As the agricultural journey continues, this article highlights that seeds are not mere commodities but catalysts for progress, resilience, and abundance
Apport des modèles mathématiques et big data pour la prise de décisions de l'entreprise; le cas d'épidémies telles que le SARS-CoV-2 dans le secteur de la santé au Chili
Authors: Matheu Alexis , Juica Paola
Published: September 2023

La pandémie causée par le virus COVID-19 a fait l'objet de nombreuses analyses et études en raison de ses incidences et conséquences graves dans tous les secteurs du développement humain au niveau mondial. Les données rendent compte de son impact non seulement sur le taux de mortalité mais aussi sur les indices économiques des pays. Lorsque l'on analyse tous ces indicateurs, on se demande si certains d'entre eux, tels que le nombre d'incidences et les variables du facteur reproductif effectif de maladie, ne peuvent pas mieux refléter la prédictibilité des cas et ainsi évaluer les mesures permettant d'atténuer l'incidence de nouveaux cas. Cette analyse est particulièrement significative si l'on considère que la pandémie n'est pas terminée et que de plus importantes et meilleurs résolutions sont encore nécessaires pour faire face à la crise en cours. Dans ce contexte, notre étude se propose d'analyser, à partir des modèles théoriques mathématiques, l'apport de ce secteur de la science pour trouver et prévoir de possibles solutions afin de diminuer les effets de cette pandémie. Pour cela, nous utiliserons des analyses statistiques basées sur trois modèles, phénoménologiques non linéaires, configuration de données et modèle logistique généralisé, en espérant qu'ils contribueront à une meilleure évaluation et compréhension des mesures prises face à la crise sanitaire et qui seront adoptées à l'avenir pour faire face à de nouveaux virus, en utilisant mieux les données et les outils technologiques dont dispose l'humanité.
Évolution de la liberté économique dans les pays d'Amérique du Sud et de l'Union Européenne durant les années 1996-2022
Authors: Lach Bartłomiej , Malaga Krzysztof
Published: September 2023

L'objectif de l'article est de décrire et d'évaluer l'évolution de la liberté économique dans les pays d'Amérique du Sud3 et de l'Union Européenne4 dans les années 1996-2022. La base d'inférence sont les coefficients de liberté économique publiés depuis 1995 par The Heritage Foundation à Washington et Wall Street Journal pour 184 pays à travers le monde. L'analyse comparative est effectuée par pays et en trois sous-groupes, qui sont : les pays d'Amérique du Sud, les pays européens qui ont rejoint l'Union européenne avant 2003 (EU1) et après 2003 (EU2). Dans la recherche empirique, les méthodes d'analyse de corrélation, σ-convergence, σ-divergence et analyse comparative multivariée sont utilisées. Le programme R et les packages dtw et dtwclustsont sont également appliqués. En conséquence, une évaluation approfondie de l'évolution de la liberté économique a été réalisée dans les 41 pays évalués, ainsi que séparément dans les trois groupes de pays analysés. Il a été montré qu'en termes de liberté économique, les pays de la EU1 l'emportent sur les pays de la EU2 et d'Amérique du Sud. En conclusion on présente remarques générales sur la relation entre les étapes des changements dans la liberté économique et les réformes institutionnelles visant une démocratisation plus complète des pays et le développement d'une économie de marché moderne.
Prévision à court terme en temps réel de l'épidémie de COVID-19 à Cuba en utilisant la modélisation
Authors: Sebrango Carlos , Sánchez Lizet
Published: September 2023

En l'absence d'information fiable sur les mécanismes de transmission d'une infection émergente, de simples modèles phénoménologiques peuvent apporter une estimation précoce de l'étendue potentielle d'épidémies en temps réel. Un avertissement sur la taille finale d'une épidémie et en particulier de la COVID-19 actuellement actif peut servir aux autorités sanitaires pour y faire face. Une variété de modèles non-linéaires ont été développés pour définir les cas cumulés de maladies épidémiques infectieuses (e.g. Richards, logistique, modèles Gompertz). Tous ces modèles peuvent utiliser correctement les données pour obtenir des prévisions à court terme en temps réel. Typiquement, il s'agit de suivre la procédure d'estimation post-sélection, i.e., de sélectionner un modèle parmi tous ceux disponibles et d'ignorer ceux reposant sur l'incertitude dans l'estimation et l'inférence vu que ces procédures sont basées sur un seul modèle. Dans ce travail, nous établissons une prédiction en temps réel de la taille finale, point crucial de l'épidémie, et des prévisions 10 jours à l'avance de cas cumulatifs en utilisant plusieurs modèles non-linéaires où ces paramètres sont estimés via modélisation. La méthode est appliquée à l'épidémie de COVID-19 en 2020 à Cuba.
Élaboration et approbation d'un index global intellectuel capital orienté sur le sujet pour une analyse comparative sur tout le pays
Authors: Parshintsev Alexander A.
Published: September 2023

De nos jours, l'apprentissage, la formation, les innovations et la numérisation sont devenus des facteurs clés du développement. Dans ces conditions, le capital intellectuel devient l'un des éléments de base qui formatent la compétitivité économique. En supposant que le capital intellectuel contribue à la réalisation de la majorité des objectifs de développement durable, la réalisation d'une évaluation complexe du capital intellectuel revêt un intérêt particulier. L'étude est consacrée à l'élaboration de la méthodologie de calcul de l'indicateur global intégral pour évaluer le niveau de capital intellectuel qui pourrait être utilisé pour une analyse comparative entre les pays. Les auteurs présentent leurs suggestions sur les éléments de l'indice, le contenu et la structure même du capital intellectuel au niveau macro ; l'élaboration d'un système d'indicateurs statistiques pour évaluer l'état et le développement du capital intellectuel sur la base de l'analyse et de la synthèse des données disponibles, en tenant compte de l'expérience internationale dans le contexte du développement de l'innovation ; le développement d'un indice global intégral du capital intellectuel pour les comparaisons entre les pays. Les résultats de l'analyse expresse basée sur la liste restreinte d'indicateurs sont également présentés, mettant en évidence les leaders et les retardataires en 2016 y 2020.
Modèle logistique de désertion à travers des techniques de régression et un arbre de décision pour l'efficience dans la destination des ressources : Le cas d'une université privée chilienne
Authors: Gutiérrez Bastián , Cortés Roberto , Dehnhardt Macarena
Published: September 2023

Lorsque l'éducation est devenue un droit fondamental qu'il faut conserver et consolider, une problématique apparait, qui a suscité de nombreuses discussions académiques et qui prétend considérer de manière holistique et critique le phénomène de massification croissante des offres de formation, manifesté dans l'augmentation exponentielle de l'accès au troisième cycle. Certaines approches postulent que, non seulement il est nécessaire d'implémenter des politiques pour amplifier la couverture de l'accès, mais il faut aussi se pencher sur la qualité de l'éducation, en considérant la désertion et la rétention universitaire. Dans ce contexte, cette recherche vise à établir un modèle d'analyse qui permette le développement de la rétention et la prévention des causes de désertion. Nous emploierons pour cela la méthodologie d'apprentissage supervisé déterminant les variables d'analyse à travers las techniques de régression et un arbre de décision, en créant un modèle logistique de désertion, capable d'améliorer l'efficience dans la destination de ressources. Finalement, ce travail visera à apporter une meilleure compréhension des phénomènes associés à la désertion et la rétention universitaire, pour aider dans la gestion et le processus de prise de décisions par les institutions d'enseignement supérieur.
Concurrence dans la distribution au détail de combustibles liquides: Exploration de la dimension spatiale
Authors: Castillo Pedro
Published: September 2023

Ce travail vise à étudier le niveau de concurrence spatiale entre les stations-services existant sur le marché de distribution au détail des combustibles liquides, à partir de l'analyse comparée de leur positionnement géospatial et de leur influence et variations de prix sur le marché national. Dans le cas du Chili, l'industrie se caractérise par sa forte concentration en nombre de fournisseurs et intégration verticale avec les segments de distribution de gros, transport et stockage, d'où l'importance de l'analyse en matière de concurrence. De plus, il existe une grande différenciation des produits en termes de localisation géographique, ce qui rend l'analyse spatiale essentielle. Ainsi, nous avons analysé en premier lieu l'impact du nombre de stations proches, du même réseau, et d'un réseau rival ou indépendants. Les résultats sont configurés selon deux approches. La première conclut que los résultats numériques sont consistants dans la dynamique des prix et le positionnement territorial des stations, car il apparait que les stations indépendantes ont un effet négatif sur le niveau de prix dans un rayon de 20 minutes, avec un réseau-action moyen de 0,19%. De même, on note un impact supérieur sur la distribution d'essence de 93 octanes et le Diesel que de l'essence de 97 octanes, car les segments de Diesel et 93 octanes sont les plus compétitifs de l'industrie, et dans le contexte où les stations indépendantes participent le plus. Dans la deuxième, les résultats montrent le rôle dominant de l'entreprise Copec : ce réseau est celui de plus grande influence négative sur le niveau des prix de ses rivales. Comme dans le premier modèle, les résultats varient par type de combustible, le rôle des réseaux d'essence de 97 octanes étant le plus important. Les résultats sont hétérogènes au niveau régional, plus élevés dans les zones géographiques densément peuplées par rapport aux zones australes et éloignées des principaux centres urbains.
The use of mobile health applications in empowering self-management of type 2 diabetes: a literature review
Authors: ÖCAL Pelin
Published: September 2023

The use of mobile health applications is vital for achieving glycemic control, promoting lifestyle changes, and empowering self-management in individuals with type 2 diabetes. This literature review aims to assess the effectiveness of mobile health applications in empowering self-management among type 2 diabetes patients. A thorough search was conducted in databases like PubMed, CINAHL, Web of Science, Cochrane Library, Scopus, ULAKBIM National Database, and Medline between January 2020 and March 2023, using keywords such as "mobile health, mobile applications, type 2 diabetes, diabetes self-management, nursing." The search yielded 525 articles, out of which 34 studies in Turkish or English that evaluated the effectiveness of mobile health applications in individuals aged 18 years and above with type 2 diabetes were included in the review. Recent studies demonstrate a growing utilization of mobile health applications for the management of treatment and care in individuals with type 2 diabetes. These applications have been shown to empower self-management by promoting dietary adherence, regular blood sugar monitoring, regular physical activity, reduced medication requirements, and decreased HbA1c levels. Additionally, mobile health applications have been found to reduce face-to-face counseling time and healthcare costs. In conclusion, mobile health applications offer promising solutions for improving self-management and healthcare outcomes for individuals with type 2 diabetes. Further research and continued integration of these applications into clinical practice are essential to optimize their benefits and address the challenges faced by diabetes patients worldwide.
Preliminary bibliometrics of plant-derived health foods over the last decade in the Scopus database
Authors:   Landmark University, Osemwegie OO , Olaniran AF ,   Landmark University, Folorunsho JO ,   Landmark University, Nwonuma CO ,   Landmark University, Ojo OA ,   Landmark University, Adetunde LA ,   CK. Tedam University of Technology and Applied Sciences, Alejolowo OO ,   Landmark University, Oluba OM ,   Landmark University, Daramola FY ,   Cape Peninsula University of Technology
Published: September 2023

A growing interest in the medicinal values of foods can be assessed by the rapidity of research publications on foods that exert health benefits. Many foods that are of health benefit to humans, irrespective of their origin (plants, animals) and subjected level of processing (fermentation, cooking, warming, freezing, vacuum-packaging), are variously designated in scientific literature based on their biofunction. Plant-based foods’ application vagaries, momentum, and research orientation regarding their health functionality awareness are scarcely studied by bibliometrics from a global perspective. Therefore, a bibliometric search was performed on the Scopus database from 2011 (January) to 2021 (April) using a range of search keys covering reports of conceptualized consumable plant-derived foods with health-promoting potential. A total of 362,309 documents on medicinal foods of plant origin were obtained from the database. The data were obtained in comma-separated values (CSV) format and analyzed with Microsoft Excel tools. Of the total documents from the Scopus database on the study, 8.01% (29,036) were contributed by African researchers. Comparatively, lead contributors (global; Africa) by group disciplines include biochemistry, genetics, and molecular biology (118,896; 8,236); pharmacology, toxicology, and pharmaceutics (104,530; 8,581); agricultural and biological sciences (99,053; 9,610), respectively. Similarly, lead contributors by country include China (73,977), India (44,898), USA (44,582), and Nigeria (4,680). This observation shows a higher research propensity towards plant-derived medicinal foods in populous nations due to factors like dietary culture, an increase in vegan and health-nutrition enthusiast populations, and the emergent concerns with the therapeutic use of synthetic pharmaceuticals. The analyzed results gave insights into the research orientation of plant-based foods that promote human health on a global stage and provide future research directions. Knowledge of the various application of plant-based foods may potentiate the United Nations Sustainable Goals initiative on responsible consumption (SDG 12), and health and wellbeing (SDG 3) among the global population. Key words: medicinal plants, health food, nutraceuticals, dietetics, indexation, health, bibliometrics