bluuebunny/crossref_metadata_2025 huggingface dataset:
Lemierre’s Syndrome with Facial Vein Thrombosis and Pulmonary Septic Emboli: A Case Report
Authors: Maia Mariana , Catarino Sara , Freitas Catarina , Castro Carolina , Correia Claudia , Pereira Marco , Pires da Silva Sara
Published: June 2022

Introduction: Lemierre’s syndrome (LS) is a rare and serious condition that often affects school-aged children, adolescents, and healthy young adults. It is defined as an oropharyngeal infection with secondary septicemia, internal jugular vein thrombosis, and septic emboli. Rare cases of atypical LS in which thrombosis occurs in other locations have been reported. Case Presentation: We presented a case of an adolescent with fever, sore throat, and neck tenderness. Physical examination revealed acute pharyngitis and bilateral small cervical lymph nodes. Rapid antigen group A Streptococcus and viral serologic tests were negative. Complete hemogram and blood biochemical analysis showed leukocytosis and elevated serum C-reactive protein (CRP). Cervical computerized tomography (CT) scan revealed a heterogeneous right tonsil and small cervical lymph nodes. The chest radiograph was normal. After admission, the adolescent started complaining of dyspnea and thoracic pain and had a painful small cervical right mass. In the thoracic CT angiography (CTA), several pulmonary septic emboli were apparent throughout the pulmonary parenchyma. Cervical Doppler ultrasound showed right facial vein thrombophlebitis, later confirmed in a CTA. Thromboses in other locations, including the internal jugular vein, were excluded, as well as cervical abscesses. The patient was successfully treated with intravenous antibiotic therapy and anticoagulation. Discussion: To this date, no reports of LS presenting with isolated thrombosis of the facial vein have been described in pediatric patients. We highlighted the importance of early recognition of LS and its atypical variants. Pediatric international guidelines regarding its management and treatment would also greatly affect the outcome of these patients.
Age and gender difference in ICT literacy and biometrics knowledge
Authors: Tomáš Doseděl  , Marcela Petrová Kafková  , Lucie Vidovićová
Published: June 2022

Accelerated digitalization during the COVID-19 pandemic and the transition from mobile phones to smartphones have increased the need for ICT literacy among the general public, including knowledge of the potential risks and their management. Generally, it is assumed that some population groups are more at risk of being left behind. Original empirical data collected in autumn 2020 as part of the PRECOBI project were used to identify the sociodemographic groups at risk of insufficient knowledge of biometrics and ICT safety. The novelty Biometrics Knowledge and ICT Safety Index (BIKIS index) was constructed to identify these and analyzed in the context of the Czech Republic. The OLS regression shows that the combination of higher age and lower education is associated with the highest risk of digital illiteracy, potentially resulting in digital exclusion. Regarding biometrics and ICT safety knowledge, the age of 50 is the cut-off point, with those with elementary and lower secondary education at a disadvantage compared to those with higher levels of education. The results show that in terms of ICT literacy, old age starts considerably earlier than in other societal contexts, which is important to note when designing ICT and biometrics-related risk mitigation strategies. The role of early life educational attainment should be supported to ensure ICT literacy in later life.
Git - gestão integrada de território na região do Conorte: implementação do projeto “Espírito Santo Sem Lixão"
Authors: Motta Helaine do Amaral , Nunes Marcus Antonius da Costa
Published: June 2022

Novas reflexões sobre o paradigma da sustentabilidade se fazem necessárias, para o alcance das soluções e avanço dos desafios estruturais e operacionais, e para isso surge o GIT – Gestão Integrada de Território. A GIT surge como proposta de realinhamentos dos objetivos da sustentabilidade se mostra como um caminho, uma alternativa para suplantar os gargalos que se interpuseram para o alcance do desenvolvimento sustentável. Objetiva-se neste contexto a busca por informações que caracterizam a GIT e as suas formas de atuação econômica x social partindo de premissas e leis que garantam a sua atividade. A metodologia adotada para o desenvolver deste, partiu da pesquisa bibliográfica a partir de livros, artigos, revistas, internet e outros materiais que focam o tema em desenvolvido. Portando conclui-se que a complexidade econômica, social, ambiental e cultural de um território demanda por uma estratégia integrada, uma ferramenta como a GIT, que combina diferentes ações de ministérios, Governos estaduais e municipais, empresas e sociedade, consolidando as relações federativas e tornando mais eficiente a ação do poder público nos territórios não se limitando em atacar problemas específicos mais sim com uma área de ação ampliada e a integração de todos os espaços e atores envolvidos
Indicadores Socioambientais como subsídio à prevenção e controle da Dengue
Authors: Feitosa Flávia Regina Sobral , Sobral Ivana Silva , Jesus Edilma Nunes de
Published: June 2022

Este trabalho teve como objetivo selecionar indicadores ambientais, econômicos e sociais que auxiliem a gestão municipal da saúde de Aracaju a redirecionar o olhar sobre o seu território de cuidado, de forma mais participativa e integrada, segundo o conceito ampliado de saúde. A área de estudo foram dois bairros do município citado: Jabotiana e Cidade Nova. A concepção teórico-metodológica utilizada foi a abordagem integrada, por abranger às dimensões, ambientais, econômicas, políticas e sociais. Trata-se de um estudo descritivo de natureza qualitativa, realizado por meio da coleta e análise de dados bibliográficos e documentais. Os indicadores foram selecionados com base na metodologia Pressão – Estado – Impacto/ Efeito – Resposta (PEI/ER) baseada no modelo Pressão/Estado/Resposta (PER) da Organização para a Cooperação e Desenvolvimento Econômico (WINOGRAD, 1996). Acrescentou-se aos indicadores selecionados, os indicadores prospectivos, que consistem na proposição de ações que poderão auxiliar a gestão na problemática apresentada. Assim, foi gerada uma matriz de vinte e seis indicadores, que poderá servir de ferramenta para o planejamento das ações da vigilância epidemiológica. Espera-se que este estudo possa subsidiar a avaliação das causas e efeitos de incidência dessa doença, podendo contribuir nas políticas públicas de prevenção e controle da infestação pelo Aedes aegypti.
Requirements for event-driven architectures in open BIM collaboration
Authors: Esser S. , Abualdenien J. , Vilgertshofer S. , Borrmann A.
Published: June 2022

Current practice of BIM-based collaboration relies on the exchange of entire domain models, which are managed and shared using Common Data Environments. Such platforms are well standardized in terms of states, roles, and participants. However, the coordination of changes by exchanging entire models requires manual identification of any added, modified, or deleted information from one shared version to another. This paper proposes the application of an eventdriven system architecture, which is in widespread use in modern communication systems. Combining the publish-subscribe design pattern, patch-based update mechanisms for BIM models, and the established concept of asynchronous, decentralized collaboration in BIM projects can significantly ease the process of understanding design changes and reduce the overall overhead of information already shared in previous versions among project members.
Enabling Federated Interoperable Issue Management in a Building and Construction Sector
Authors: Oraskari J. , Schulz O. , Werbrouck J. , Beetz J.
Published: June 2022

A Common Data Environment (CDE)is an agreed-upon source of information on building-related projectsto collect, manage,and exchange data between stakeholders. Theapproach in the AEC domain is to usebuildingSMART’sBIM Collaboration Format (BCF)as thedigital issue communication part ofCDEs.Contrasting with the federated nature of the AEC industry, CDEs are typically organised in a centralised fashion.This work proposes a potential transition of BCF into a distributed environment that servesas an example for further developments inthe distribution of CDEs and CDE-independent data management. We show how a single source of truth over the project data and the advantages of the central approach can be realised in a distributed setupusing a Solid architecture environment,enablingdecentralised authentication and stakeholders’ability to control their data.
Design and validation of a mobile structural health monitoring system based on legged robots
Authors: Smarsly K. , Worm M. , Dragos K.
Published: June 2022

Structural health monitoring (SHM) has been witnessing the transition from cable-based systems to wireless systems, owing to the reduced installation costs and efforts of wireless sensor nodes. However, reliable information on civil infrastructure requires dense arrays of wireless sensor nodes, which may nullify the merits of wireless SHM. This paper proposes a mobile SHM system, comprising maneuverable quadruped robots equipped with sensors for collecting, processing, and analyzing structural response data. The mobile SHM system is validated through field tests on a pedestrian bridge, proving that a minimum deployment of quadruped robots yields the same structural information as an array of wireless sensor nodes. Furthermore, the tests results are compared to results obtained from a benchmark SHM system, showcasing the accuracy of the mobile SHM system. The proposed mobile SHM system marks an advance towards employing fully autonomous robotic fleets for SHM in lieu of stationary wireless sensor nodes.
Investigation of the potential antitumor activity of PLK1 inhibitor SBE13 in colon cancer cell line HT29
Authors: GÖMEÇ Muhammed , YULAK Fatih , ERGÜL Mustafa
Published: June 2022

Background: High levels of Polo-like kinase 1 (PLK1), which have been found to be abnormally expressed in many tumor types, are known to contribute to tumorigenesis and poor prognosis. Therefore, specific targeting of PLK1 is an important strategy for cancer therapy. In this study, it was aimed to investigate the cytotoxic effect of SBE13, one of the PLK1 inhibitors, against HT29 colon adenocarcinoma cells and its apoptotic potential.

Methods: The cytotoxic effect of SBE13 on HT29 was determined by XTT colorimetric assay. Flow cytometry was also used to determine apoptosis.

Results: SBE13 showed a dose-dependent cytotoxic effect in HT29 cells and its IC50 value was calculated as 11.79 µM for 48 h. Moreover, the Annexin V binding assay revealed that SBE13 treatment significantly increased the apoptosis in HT29 cells.

Conclusion: Generally, SBE13 exerts a cytotoxic effect promoted by apoptosis in colon cancer cells HT29. Although the anticancer efficacy of SBE13 in colon cancer is promising, this potential effect should be reinforced by further studies.
Influence of Age on Arterial Stiffness among Healthy Pregnant Women: A Cross-sectional Study
Authors: Gupta Nitesh Kumar , Sangolli Laxmi , Patil Sumangala M , Khodnapur Jyoti P
Published: June 2022

Introduction: Normal pregnancy is associated with physiological cardiovascular system adaptations. Previous studies stated that physiological changes like arterial vasodilatation occurs for successful results for both mother and baby during pregnancy. Also, increased arterial stiffness during pregnancy causes several disorders, such as Pregnancy-Induced Hypertension (PIH) and foetal growth restriction. Aim: To evaluate the influence of age on arterial stiffness among third-trimester healthy pregnant women using Pulse Wave Velocity (PWV). Materials and Methods: This cross-sectional observational study was conducted at BLDE (University), Vijayapur, Karnataka, India, between April 2019 to July 2019. A total of 60 pregnant women were screened and 48 healthy pregnant women between 20-40 years with resting blood pressure <140/90 mmHg, non smokers and subjects not taking medications were included in the present study. The sample size was divided into four groups (Group 1: 20-24 years; Group 2: 25-29 years Group 3: 30-34 years; and Group 4: 35-40 years). Each group contained 12 participants and vascular stiffness parameters like brachialankle PWV (b-a PWV) and carotid-femoral PWV (c-f PWV) were evaluated. Statistical analysis was done using Statistical Package for the Social Sciences (SPSS) software 16.0 version. Comparison between the mean values was done using Analysis of Variance (ANOVA) and Post-Hoc test (LSD) and correlation was assessed using Pearson’s correlation test. The p-value ≤0.05 was considered significant. Results: Mean and standard deviation of b-a PWV (Group 1: 934.82±97.66; Group 2: 970.27±101.92; Group 3: 1077±112.20; Group 4: 1563.2±143.47) c-f PWV (Group 1: 574.78±62.81; Group 2: 662.26±61.88; Group 3: 769.88±65.51; Group 4: 967.96±70.52) showed statistically significant (p<0.001) increase in both b-a PWV and c-f PWV with age among third trimester healthy pregnant women. Pearson’s Correlation test showed significant positive correlation between b-a PWV (r=0.516, p<0.001) and c-f PWV (r=0.532, p<0.001) with age among third trimester pregnant women. The values of present study observed increase in both b-a PWV and c-f PWV with age. Conclusion: Increased arterial stiffness with age among pregnant women, as assessed by PWV, predates the development of cardiovascular risk in women. This study may help obstetricians to reduce cardiovascular complications due to pregnancy in different age groups by suggesting regular physical activity, relaxation techniques and a healthy lifestyle to pregnant women in the early stage.
Influence of Potassium and Sulphur on Growth and Yield of Greengram (Vigna radiata. L)
Authors: Akhil Guggilla , Debbarma Victor , Tejaswi Addanki
Published: June 2022

The experiment was conducted during Zaid season 2021 at KVK, SHUATS, Prayagraj (U.P.) to study the influence of potassium and sulphur on growth and yield of greengram. The treatments consist of potassium 15, 25, 35 kg/ha and sulphur 10, 20, 30 kg/ha. The result reported that application of potassium 35 kg/ha + sulphur 30 kg/ha (Treatment 9) recorded significantly highest Plant height (45.77 cm), maximum number of branches (6.50), maximum number of nodules (21.73), maximum plant dry weight (9.66 g). It is also observed that the maximum grain yield (1,109.67 kg/ha) and stover yield (2,431.00 kg/ha) was obtained with the application of potassium 35 kg/ha along with sulphur 30 kg/ha. It was concluded that application of potassium and sulphur performs positively and improves growth and yield parameters of Greengram.
Effect of Different Levels of Mycorrhization on the Growth Parameters and Nutrient Content of Chilli
Authors: Sarita . , Kumar Rakesh , Mehta Satish , Sharma Lochan , Yadav Pankaj
Published: June 2022

Aim: To evaluate the effect of different levels of Glomus mosseae on plant growth parameters chlorophyll content, mycorrhizal colonization (%), sporocarp number and nutrient content of chilli.

Study Design: The experiment was conducted using a complete randomized design (CRD).

Study Area: To study the mycorrhizal effect on the chilli plants, observations were documented in Sceenhouse and laboratory conditions. Plant Pathology Laboratory, CCS HAU, Hisar was use for the laboratory work. The experiment was undertaken during crop season 2018

Methodology: Mycorrhizal fungi was raised and maintained on wheat and pearl millet in earthen pots. Further experiment was conducted and Plant height, Root length, Dry weight of root and shoot, Mycorrhizal colonization, Sporocarp number, SPAD chlorophyll content and NPK content was observed.

Results: Mycorrhiza is a symbiotic association between a fungus and the root system of vascular plants. Mycorrhizal associations help the host plants to thrive in adverse soil conditions and drought situations by increasing the root surface area and nutrient uptake efficiency. In the present study Glomus mosseae was tested on chilli plant with different inoculum levels (100, 150, 200 and 400 chlamydospores/kg soil) and found that Plant height, Root length, Dry weight of root and shoot, SPAD chlorophyll content, per cent mycorrhizal colonization and sporocarp number were maximum when 400 spores were used for inoculation and minimum were found in untreated plants. Among all the four observation period i.e. 30, 45, 60 and 90 days after transplanting maximum NPK content was observed at 90 days after transplanting.

Conclusion: Among All the inoculum levels (100, 150, 200 and 400 chlamydospores/kg soil) maximum plant growth parameters, NPK content and chlorophyll content was observed when 400 chlamydospores/kg soil were used.
Role of Surface APRIL (A Proliferation Inducing Ligand, CD256) Expression in Patients with Rheumatoid Arthritis
Authors: Raboh Hanaa Mohammed Abd , Saadany Hanan Mohammed El , Mabrouk Maaly Mohamed , Nofal Hanaa El-Sayed
Published: June 2022

Background: A Proliferation Inducing Ligand (APRIL) is a member of the tumour necrosis factor (TNF) superfamily and is released by activated T and B cells, monocytes, dendritic cells, macrophages, neutrophils, myelocytes, astrocytes, and adipocytes. The aim of the study was to evaluate the APRIL; CD256 surface expression on circulating monocytes in rheumatoid arthritis (RA) patients and disease activity.

Methods: This case control study was conducted on 60 subjects They were classified into two groups: group 1: 20 apparently healthy subjects as a reference group., group 2: 40 patients with RA according to DAS28, they were subdivided into two equal subgroups: active rheumatoid arthritis. and inactive rheumatoid arthritis

Results: There was a statistical increase in surface APRIL expression in active group and inactive group when compared to normal controls and there was also statistical increase in surface APRIL expression level in active group when compared to inactive group. There was no significant correlation between surface APRIL expression with RF (p=0.745) Anti CCP (p=0.375), Hb (p= 0.056), PLT (p= 0.980), WBCs (p= 0.252), AMC (p= 0.890).

Conclusions: Surface APRIL expression is increased on circulating monocyte subsets in RA patients where it is highly correlated with the activity of the disease. Monocytes in patients with RA is shifted toward intermediate and non-classical monocytes, populations of monocytes known to produce the inflammatory cytokines TNF-α important in the pathogenesis of RA.
An Ultrafast Self‐Polarization Effect in Barium Titanate Filled Poly(Vinylidene Fluoride) Composite Film Enabled by Self‐Charge Excitation Triboelectric Nanogenerator
Authors: Wang Jian , Wu Huiyuan , Wang Zhao , He Wencong , Shan Chuncai , Fu Shaoke , Du Yan , Liu Hong , Hu Chenguo
Published: June 2022

Although charge excitation is an effective approach to achieve high charge density for triboelectric nanogenerators (TENGs), high output charge is limited by air‐breakdown. Due to capacitor structure, there are two ways to reduce the influence of air‐breakdown in TENG: decrease in thickness and increase in permittivity of dielectric film. Obviously, the increase in permittivity is more reliable in applications. Herein, a double‐layer TENG shared with one floating metal electrode is proposed, on which charge is injected by a self‐excitation circuit. An ultrafast self‐polarization effect is found in two barium titanate filled poly(vinylidene fluoride) composite films in the TENG by high electrical field produced from the floating electrode. According to comparison and analysis, the speed of polarization to saturation of dielectric composite films in self‐charge excitation approach is ≈3 times faster than that of external‐charge excitation. Optimization of various parameters is investigated to enhance the output performance of the TENG. A large output charge density of 1.67 mC m–2 is achieved in the atmosphere with 40% relative humidity due to self‐polarization effect of the dielectric composite film. This study provides insights into understanding the polarized behavior of molecules in dielectrics and further optimizing the output performance of TENGs in self‐charge excitation systems.
Giant Nonlinear Optical Response of Graphene Oxide Thin Films Under the Photochemical and Photothermal Reduction
Authors: Ma Xiaoguang , Wang Yimeng , Hao Xiaojian , Gu Min , Zhang Qiming
Published: June 2022

Thin graphene oxide (GO) films have been widely explored for their outstanding optical properties, especially their large optical nonlinear coefficients, and high tunability of optical nonlinear coefficients under photoreduction. In this work, an experimental observation of giant nonlinear optical response in GO films under two different photoreduction mechanisms is reported. After ultraviolet (UV) light‐induced photochemical reduction and continuous wave (CW) laser‐induced photothermal reduction, the nonlinear optical response of reduced graphene oxide (rGO) via the Z‐scan method using a femtosecond laser beam at a wavelength of 800 nm is characterized. The rGO exhibits a giant optical nonlinearity, especially two‐photon absorption (TPA). A giant TPA coefficient of rGO on the order of ≈105 cm GW−1 is obtained under two photoreduction mechanisms (photochemistry and photothermal). This is the first time that a large enhancement effect of TPA has been observed in graphene‐based materials, and the TPA coefficient is an order of magnitude higher than the highest value previously reported. The versatile optical nonlinear properties imply a huge potential of the GO film in advanced photonic and optoelectronic devices such as broadband ultrafast optical switching and optical limiting.
Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes
Authors: Saito Naoto , Haniu Hisao , Aoki Kaoru , Nishimura Naoyuki , Uemura Takeshi
Published: June 2022

Over the past 15 years, numerous studies have been conducted on the use of nanocarbons as biomaterials towards such applications as drug delivery systems, cancer therapy, and regenerative medicine. However, the clinical use of nanocarbons remains elusive, primarily due to short‐ and long‐term safety concerns. It is essential that the biosafety of each therapeutic modality be demonstrated in logical and well‐conducted experiments. Accordingly, the fundamental techniques for assessing nanocarbon biomaterial safety have become more advanced. Optimal controls are being established, nanocarbon dispersal techniques are being refined, the array of biokinetic evaluation methods has increased, and carcinogenicity examinations under strict conditions have been developed. The medical implementation of nanocarbons as a biomaterial is in sight. With a particular focus on carbon nanotubes, these perspectives aim to summarize the contributions to date on nanocarbon applications and biosafety, introduce the recent achievements in evaluation techniques, and clarify the future prospects and systematic introduction of carbon nanomaterials for clinical use through practical yet sophisticated assessment methods.
Hydrazine Hydrate‐Induced Surface Modification of CdS Electron Transport Layer Enables 10.30%‐Efficient Sb2(S,Se)3 Planar Solar Cells
Authors: Li Jianmin , Zhao Yuqi , Li Chuang , Wang Shaoying , Chen Xueling , Gong Junbo , Wang Xiaomin , Xiao Xudong
Published: June 2022

Antimony selenosulfide (Sb2(S,Se)3), a simple alloyed compound containing earth‐abundant constituents, with a tunable bandgap and high absorption coefficient has attracted significant attention in high‐efficiency photovoltaic applications. Optimizing interfacial defects and absorber layers to a high standard is essential in improving the efficiency of Sb2(S,Se)3 solar cells. In particular, the electron transport layer (ETL) greatly affects the final device performance of the superstrate structure. In this study, a simple and effective hydrazine hydrate (N2H4) solution post‐treatment is proposed to modify CdS ETL in order to enhance Sb2(S,Se)3 solar cell efficiency. By this process, oxides and residual chlorides, caused by CdCl2 treated CdS under a high temperature over 400 °C in air, are appropriately removed, rendering smoother and flatter CdS ETL as well as high‐quality Sb2(S,Se)3 thin films. Furthermore, the interfacial energy band alignment and recombination loss are both improved, resulting in an as‐fabricated FTO/CdS‐N2H4/Sb2(S,Se)3/spiro‐OMeTAD/Au solar cell with a high PCE of 10.30%, placing it in the top tier of Sb‐based solar devices. This study provides a fresh perspective on interfacial optimization and promotes the future development of antimony chalcogenide‐based planar solar cells.
Integrating the right to food in sustainability standards: A theory of change to move global supply chains from responsibilities to impacts
Authors: Beuchelt Tina D. , Schneider Rafaël , Gamba Liliana
Published: June 2022

To address the undesired environmental and social impacts of agricultural export production, the agricultural industry increasingly relies on sustainability standards. These standards neglect food security, although rights‐based food security criteria were recently developed. This research analyses the responsibilities of global supply chain actors for the Right to Food and identifies a feasible implementation pathway to support the operationalization of these criteria. Based on qualitative research, a theory of change was developed and tested in six case studies across the globe. The theory of change discusses relevant stakeholders, necessary changes, expected impacts, and emphasizes the role of market demand and institutional frameworks.
A Collapsible Soft Actuator Facilitates Performance in Constrained Environments
Authors: Rogatinsky Jacob , Gomatam Kiran , Lim Zi Heng , Lee Megan , Kinnicutt Lorenzo , Duriez Christian , Thomson Perry , McDonald Kevin , Ranzani Tommaso
Published: June 2022

Complex environments, such as those found in surgical and search‐and‐rescue applications, require soft devices to adapt to minimal space conditions without sacrificing the ability to complete dexterous tasks. Stacked balloon actuators (SBAs) are capable of large deformations despite folding nearly flat when deflated, making them ideal candidates for such applications. This paper presents the design, fabrication, modeling, and characterization of monolithic, inflatable, soft SBAs. Modeling is presented using analytical principles based on geometry and then using conventional and real‐time finite‐element methods. Both one and three degree‐of‐freedom (DoF) SBAs are fully characterized with regard to stroke, force, and workspace. Finally, three representative demonstrations show the SBA's small‐aperture navigation, bracing, and workspace‐enhancing capabilities.
Successful establishment of endangered springsnails following habitat enhancement and translocations
Authors: Johnson William P. , Beauchamp Jeffrey S. , Butler Matthew J. , Sanchez Jeffrey I.
Published: June 2022

Spring‐associated aquatic invertebrates tend to be narrow‐range endemics. Globally, they are threatened with extinction as a result of habitat loss caused by declining aquifers and by climate change.

Extinction risks to narrow‐range endemics may be reduced by having multiple, separate populations, yet there have been few attempts to use conservation translocations to create new populations.

Pyrgulopsis roswellensis (Roswell springsnail), Juturnia kosteri (Koster's springsnail) and Gammarus desperatus (Noel's amphipod) are range‐restricted, spring‐associated endangered species. Each species has lost one or more populations owing to habitat loss, and their distributions are now largely restricted to Bitter Lake National Wildlife Refuge, New Mexico.

In 2014, Bitter Lake National Wildlife Refuge enhanced a series of springs by re‐routing a channelized section of river away from them. The goal was to create habitat suitable for establishing new populations of P. roswellensis and J. kosteri, and for expansion of G. desperatus. After assessing risks and benefits of translocations, approximately 6,177 P. roswellensis and 8,707 J. kosteri were introduced into the project area from 2015 to 2018.

Efficacy was evaluated by comparing the abundance of invertebrates in the translocation site through time, and by comparing springsnail abundance with three reference spring systems. From 2014 to 2021, invertebrates were monitored twice annually in the translocation area. In reference spring systems, P. roswellensis and J. kosteri were monitored twice annually in 2020 and 2021.

Counts of springsnails in the translocation area were comparable to one or more reference areas, which suggests that translocations were successful. In addition, the proportion of P. roswellensis, the less common springsnail, to J. kosteri was similar to references areas.

G. desperatus did not increase, which may be because some measures of water quality have not stabilized.

Globally, climate change and aquifer declines necessitate immediate consideration be given to conservation translocations as a means of keeping spring‐associated species from becoming extinct.
High Structural Stability and Reaction Mechanism of Porous Carbon Nanobox Encapsulated Monodisperse CoP Nanoparticles for High‐Performance Lithium‐Ion Battery
Authors: Cui Xiang , Liang Minxia , Wang Lei , Li Longgang , Peng Qianqian , Dong Hanghang , Qi Shuo , Sun Weiwei , Lv Li‐ping , Chen Xianfei , Wang Yong , Chen Shuangqiang , Chou Shulei
Published: June 2022

Transition metal phosphides (TMPs) are perplexed by the low electronic/ionic conductivity, volume variations, and unstable reaction interfaces. To tackle these issues, herein, we have proposed a low‐temperature phosphorization strategy by reactions between Co‐based metal‐organic frameworks (MOF) and sodium dihydric hypophosphite to encapsulate monodisperse CoP nanoparticle (∼12 nm) into MOF‐derived hollow and porous carbon nanobox (CoP@PCB). Compared to bare CoP, such CoP@PCB electrode has shown remarkable electrochemical performance, which is highly ascribed to its robust structural feature, pre‐reserved voids, monodisperse CoP nanoparticles, and stable reaction interfaces, as well as fast reaction kinetics. Moreover, the good electrochemical properties of CoP@PCB//LiFePO4 full cells have demonstrated practical possibility. The formation of Co and Li3P as discharged products has corroborated the redox conversion reaction mechanism, as assessed by in‐situ X‐ray diffractions. The favorable function of the carbon shell in boosting both electronic conductivity and lowering diffusion energy barriers has been confirmed by theoretical calculations, demonstrating an important synergistic effect.
Eight years follow‐up of a patient with triple vessel disease patient complicated with heart failure without invasive intervention for home‐based exercise rehabilitation combined traditional Chinese medicine: A case report
Authors: Zhang Sisi , Zheng Huiyang , Liu Xinyu , Meng Xiaoping
Published: June 2022

We report 8‐year follow‐up of a home‐based exercise rehabilitation program combined traditional Chinese medicine for a patient with triple vessel disease patient complicated with heart failure without invasive intervention. Improvements were observed in all outcomes.
Septic shock, acute renal and liver failure following unsafe abortion using bitter leaves and wandering jew in northern Uganda: A case series
Authors: Alobo Gasthony , Reverzani Cristina , Nahurira Violah , Sarno Laura
Published: June 2022

Unsafe abortion is a major problem in Uganda, being one of the leading causes of maternal morbidity and mortality. Abortions are performed mostly under unsafe conditions, by people without medical training. In rural areas in northern Uganda, women often resort to traditional providers, who use local herbs as abortion remedies, usually with adverse outcomes. Little is known about the biological properties of these herbs and their toxicity profile. Here, we present the case series of two women, of 31 and 24 years of age, who underwent unsafe abortion for unintended pregnancy by using herbal medicines, that is, Commelina Africana (wandering jew) and Vernonia amygdalina (bitter leaf), respectively. While the first case resulted in uterine necrosis and pelvic peritonitis, which required multiple surgical interventions and the use of reserve antibiotics, the second case resulted in liver and renal failure that led to the death of the patient. This case series describes the unusual severe toxicity of two herbal medicines that are frequently used to induce abortion in northern Uganda. It highlights possible associations of Commelina Africana (wandering jew) with uterine necrosis complicated by sepsis, and of Vernonia amygdalina (bitter leaf) with acute liver and renal failure.
Eosinophilic gastritis without peripheral eosinophilia and atopy: A case report
Authors: Mishra Aakash , Bhattarai Tulsi Ram , Mishra Aman , Poudel Shekhar
Published: June 2022

Eosinophilic gastritis (EG) is characterized by eosinophilic infiltration of any gastric layers. We report a 65‐year‐female presenting with abdominal pain and vomiting for two months. Chronic gastritis not responding to empirical treatment interrogated further investigations. In the absence of atopy and peripheral eosinophilia, successful treatment of a large solitary antral ulcer with steroids upheld the diagnosis of EG.
Rehabilitation effects of circuit resistance training in coronary heart disease patients: A systematic review and meta‐analysis
Authors: Wu Chunchun , Bu Rongsheng , Wang Yaoguo , Xu Chaoxiang , Chen Youfang , Che Lishuang , Wang Shengnan
Published: June 2022

Background and Hypothesis

The rehabilitation effect of circuit resistance training in coronary heart disease (CHD) patients remains unclear. We perform this review to examine the rehabilitation effect of circuit resistance training in CHD patients and to provide a basis for the formulation of reasonable individual exercise prescriptions for CHD patients.

Methods

Randomized controlled trials (RCTs) were searched on PubMed, Web of Science, The Cochrane Library, Embase, Clinical Trials, and CNKI. About 1232 studies were identified. Nine RCTs were finally used for the present meta‐analysis to determine the rehabilitation effect of circuit resistance training in CHD patients, compared to aerobic training. Individuals enrolled for the studies were at a mean age of 60.5 years old and were all CHD patients. Following the PRISMA guidelines, we extracted basic information about the study and patient characteristics, as well as measurements (e.g., the peak oxygen uptake, the body mass index [BMI], the body fat percentage, the systolic blood pressure, the total cholesterol, and triglycerides). Subsequently, this meta‐analysis determined the overall effect by using standardized mean difference (SMD) and 95% confidence interval (CI).

Results

Compared with aerobic training, circuit resistance training significantly decrease the BMI and the body fat percentage.

Conclusions

As suggested from the present meta‐analysis of RCTs, circuit resistance training is effective in improving the BMI and the body fat percentage in CHD patients and may help delay the progression of CHD. CRT has the advantage of lower load in most cases with a similar effect.
Metal‐Organic‐Framework‐derived Co Nanoparticles Embedded in P, N‐Dual‐doped Porous Carbon/rGO Catalyst for Water Splitting and Oxygen Reduction
Authors: Zhao Wenhua , Gong Jiangfeng , Yan Yuxiang , Wu Niandu , Zhou Boye , Ye Yongchun , Yang Shaoguang
Published: June 2022

Co nanoparticles embedded in P, N ‐dual doped porous carbon/rGO (P, N‐PCCo/rGO) were obtained through electrostatic interaction and high‐temperature pyrolysis with good electrical conductivity and ultrahigh specific surface area. At a current density of 10 mA cm−2, the overpotentials of P,N‐PCCo/rGO during acidic hydrogen evolution (HER) and alkaline oxygen evolution (OER) are 89 mV and 235 mV, respectively. The performance is significantly enhanced with increasing current density, even better than commercial Pt/C and IrO2 in electrocatalytic water splitting. Besides, P,N‐PCCo/rGO have a large half‐wave potential (∼0.872 V) and kinetic current Jk (11.76 mA cm−2) for oxygen evolution reaction (ORR). GO together with porous carbon constrains the growth of Co particles based on assisted synthesis. P, N co‐doped Co particles cause lattice defects of carbon, which form multiple active sites and provide more reaction channels for active species, thereby improving the HER, OER and ORR performance of the P,N‐PCCo/rGO trifunctional catalyst. GO‐assisted preparation of ultra‐thin porous P,N‐PCCo/rGO samples has laid a solid foundation for designing and implementing a series of multifunctional catalysts for graphene oxide‐based heteroatoms (N, P, S, etc.) doped with non‐noble metal embedded porous carbon.
Volunteers Keeping Tabs on Superheroes of the Sea: Florida's Adventure Coast
Authors: Hall-Scharf Brittany J
Published: June 2022

Horseshoe crabs (Limulidae) are ancient superheroes still walking our beaches today. Besides being a favored prey item for many fish, birds, and sea turtles, pharmaceutical companies use the horseshoe crab's unique blue blood to ensure intravenous drugs are free of harmful bacteria. Historically, horseshoe crabs thrived along Florida's extensive shoreline, but population estimates are lacking. Comprehensive surveys across all coastal habitats by paid faculty or staff are financially and logistically impossible. To address data gaps and better inform fishery managers, collaborators created the Florida Horseshoe Crab Watch program. Intricacies of this program are described, with particular emphasis on Hernando County's training regimen. This case study can inform those interested in using effective citizen science programs to answer questions where volunteer involvement may supersede available funding limitations.
Investigation of pollutant‐removal performance and energy efficiency characteristics of wet electrostatic precipitator
Authors: Liu Hanxiao , Wu Liming , Zheng Chenghang , Li Jianguo , Liu Xiaowei , Chen Zhaomei
Published: June 2022

Energy conservation and efficiency enhancement are the options to achieve carbon neutrality in coal‐fired power plants. Wet electrostatic precipitator (WESP) is an important pollutant removal and energy consumption equipment in coal‐fired power plants, which emits a large amount of CO2 indirectly and has a great potential for emission reduction. In this paper, the emission reduction characteristics of multiple pollutants and energy consumption were analyzed by collecting 158 datasets of WESP. The results showed that WESP was effective at removing PM, PM2.5, SO3, droplets, and Hg with the following concentrations at the outlet: 1–10, 3, 1–5, 15, and 5 µg/m3, respectively. The emission factors of different pollutants were sorted in the descending order of size as droplets (average value 51.59 g/MWh), PM (19.15 g/MWh), SO3 (17.32 g/MWh), PM2.5 (8.21 g/MWh), and Hg (9.74 mg/MWh). Specific power/water/alkali consumptions were found as 0.5–2.5×10–4 kWh/m3, 10 × 106 t/m3, and 0.06–9.79 ×10–8 t/m3, respectively. These consumptions were negatively correlated with the inlet concentration of PM/SO3. The average annual emission of CO2 per unit installed capacity by the application of WESP was found to be 13.88 t/MW. It was estimated that the CO2 annual emissions by using WESP in coal‐fired power plants in China were 1.68×106 t. The CO2 annual emission reduction of 7.33×105 t could be achieved through grade 2 energy efficiency WESP (7.83 t/MW) of GB/T 37484‐2019. A further reduction of 3.18×105 t could be achieved if it could be controlled at grade 1 (5.20 t/MW). This study can provide a valuable reference for the subsequent operation of ultra‐low emission units to conserve energy and reduce CO2 emissions. © 2022 Society of Chemical Industry and John Wiley & Sons, Ltd.
The orphan G protein‐coupled receptor GPR149 is a negative regulator of myelination and remyelination
Authors: Suo Na , He Bingqing , Cui Shihao , Yang Ying , Wang Min , Yuan Qianting , Xie Xin
Published: June 2022

Myelin sheath, formed by oligodendrocytes (OLs) in the central nervous system (CNS) and Schwann cells in periphery, plays a critical role in supporting neuronal functions. OLs, differentiated from oligodendrocyte precursor cells (OPCs), are important for myelination during development and myelin repair in CNS demyelinating disease. To identify mechanisms of myelin development and remyelination after myelin damage is of great clinical interest. Here we show that the orphan G protein‐coupled receptor GPR149, enriched in OPCs, negatively regulate OPC to OL differentiation, myelination, as well as remyelination. The expression of GPR149 is downregulated during OPCs differentiation into OLs. GPR149 deficiency does not affect the number of OPCs, but promotes OPC to OL differentiation which results in earlier development of myelin. In cuprizone‐induced demyelination model, GPR149 deficiency significantly enhances myelin regeneration. Further study indicates that GPR149 may regulate OL differentiation and myelin formation via MAPK/ERK pathway. Our study suggests that deleting or blocking GPR149 might be an intriguing way to promote myelin repair in demyelinating diseases.
Expression of interleukin 1, interleukin 27, and TNF α genes in patients with ischemic cardiomyopathy versus idiopathic dilated cardiomyopathy: A case‐control study
Authors: Iravani Saadi Mahdiyar , Salami Javad , Abdi Hanieh , Kheradmand Nadiya , Nabi Abdolyousefi Ehsan , Torkamani Mahmoud , Karimi Zahed , Agah Shahram , Rahimian Zahra , Manafi Alireza
Published: June 2022

Background and Aims

Congestive heart failure is a complex multifactorial syndrome due to tissue hypoperfusion that is affected by some factors like inflammatory cytokines. In our study, we investigated the exact gene expression of three inflammatory cytokines in ischemic and idiopathic cardiomyopathy patients.

Methods

From 49 studied recipients in the ischemic group, 23 (46.9%) were male and from 40 studied recipients in the idiopathic dilated cardiomyopathy group, 19 (47.5%) were male. For the quantitative analysis of interleukin (IL)‐1, IL‐27, and tumor necrosis factor (TNF)‐α messenger RNAs expression level, the SYBR Green real‐time polymerase chain reaction method was performed using SYBRPremix Ex TaqTM II (Tli RNaseH Plus; Takara) and designed primers specific for each gene in an iQ5 thermocycler (BioRad Laboratories) according to the manufacturer's instructions.

Results

Our results showed that the expression level of IL‐1 and TNF‐α were significantly higher in the ischemic patients compared to healthy controls (p < 0.001, p < 0.01, respectively); also, we found higher levels of IL‐1 and IL‐27 gene expressions in idiopathic patients compared to healthy controls (p < 0.001, p < 0.001, respectively). There were not any significant differences in IL‐1, IL‐27, and TNF‐α expression levels between ischemic patients and idiopathic ones.

Conclusion

Although we would introduce IL‐1, IL‐27, and TNF‐α as effective inflammatory cytokines on myocardial functions in ischemic and idiopathic cardiomyopathy patients, there is not any difference between these two groups in gene expression of three main inflammatory cytokines.
Aberrant TRPC1 expression reflects stromal cervical invasion, lymphovascular invasion, elevated FIGO stage, and poor survival in resectable endometrial carcinoma patients
Authors: Wang Yi , Zhang Chun
Published: June 2022

Background

Transient receptor potential channel 1 (TRPC1) promotes tumor growth and metastasis in endometrial carcinoma (EC) cell lines, whereas its clinical role in EC management remains unclear. Therefore, this study aimed to investigate the association of TRPC1 protein expression with the clinical features and survival of EC patients, then was further validated by TRPC1 mRNA measurement and data from The Human Protein Atlas.

Methods

TRPC1 protein expression in tumor tissues and normal endometria of 176 resectable EC patients was determined using immunohistochemistry. Besides, TRPC1 mRNA expression of partial patients (n = 80) was detected using RT‐qPCR. Additionally, survival data from The Human Protein Atlas (derived from The Cancer Genome Atlas [TCGA]) was analyzed.

Results

TRPC1 protein expression was up‐regulated in tumor tissue compared with normal endometrium (p < 0.001). Up‐regulated TRPC1 protein expression was associated with stromal cervical invasion (p = 0.044), lymphovascular invasion (p = 0.032), and increased federation of gynecology and obstetrics (FIGO) stage (p = 0.005). Tumor TRPC1 protein high was linked with shortened accumulating disease‐free survival (DFS) (p = 0.009) and overall survival (OS) (p = 0.026), which were also confirmed by multivariate Cox's regression analysis (both p < 0.050). Further, TRPC1 mRNA validation disclosed that TRPC1 mRNA high was related to shortened accumulating DFS (p = 0.038) and exhibited a correlating trend with declined OS (lacked statistical significance) (p = 0.162). Meanwhile, survival analysis on the data from The Human Protein Atlas (derived from TCGA) also exhibited that TRPC1 mRNA high was correlated with reduced accumulating OS (p < 0.001).

Conclusion

Our findings support TRPC1 as a prognostic biomarker in resectable EC patients.
Problem solving in fawn‐footed mosaic‐tailed rats Melomys cervinipes is not significantly influenced by maternal care or genetic effects
Authors: Rowell Misha K. , Rymer Tasmin L.
Published: June 2022

Innovative problem solving is thought to be a flexible trait that allows animals to adjust to changing or challenging environmental conditions. However, it is not known how problem solving develops during an animal's early life, or whether it may have a heritable component. We investigated whether maternal genetic and nongenetic effects influenced problem‐solving ability in a native Australian rodent, the fawn‐footed mosaic‐tailed rat Melomys cervinipes. We measured direct (time spent grooming and huddling), indirect (time spent nesting), and total amount of maternal care received across pup development (postnatal Days 1–13). We measured problem solving in juveniles using matchbox tasks, and in mothers and adult offspring using six tasks of varying complexity (matchbox, cylinder, obstruction, pillar, tile, and lever tasks). We found no relationship between any maternal care measures and problem‐solving abilities across multiple tests, suggesting limited (if any) maternal nongenetic effects. We also found that, as shown by low heritability estimates, problem solving only had a small heritable component in some tasks, but this was nonsignificant and requires further investigation. These results suggest that problem solving is unlikely to be constrained by maternal effects experienced during early development, and is, instead, more likely to be influenced by other factors (e.g., experience) later in an individual's lifetime.