bluuebunny/crossref_metadata_2025 huggingface dataset:
The Study of Entrepreneurial Leadership on Turnover Intention and Job Commitment: Mediation Effect of Strategic Flexibility
Authors:   Korean Academy of Leadership, Kim Jong Kwan , Wang Fei , Jeong Du Sim
Published: September 2022

Recently, interest in entrepreneurial leadership at home and abroad is increasing, and the importance of entrepreneurial leadership of leaders influencing organizational member behavior is being emphasized.
This study is a study on the effect of organizational members' turnover intention and job commitment based on entrepreneurial leadership, and the mediating effect of strategic flexibility. Specifically, the model of this study predicted that entrepreneurial leadership would have a negative (-) effect on turnover intention and a positive (+) effect on job commitment and strategic flexibility. It was also assumed that strategic flexibility would mediate in the relationship between entrepreneurial leadership, turnover intention, and job commitment.
For empirical analysis, online survey data submitted by 307 small and medium-sized enterprises (SMEs) located in the Beijing metropolitan area of China were used, and regression analysis was used to verify the hypothesis. According to the progress of the analysis, the mediating effect of strategic flexibility in the relationship between entrepreneurial leadership and turnover intention and job commitment as well as the effect of entrepreneurial leadership on turnover intention and job commitment was verified. These findings suggest that business practitioners should recognize the positive effects of entrepreneurial leadership and accept the need for entrepreneurial leadership education.
A Meta-analysis of the Relationship between Leadership and Followership: Focusing on Research in Korean Journals
Authors:   Korean Academy of Leadership, Jun Sun Ho , Park Sang Wook , Kim Hee Bong
Published: September 2022

The purpose of this study is to provide theoretical and practical implications through the meta－analysis on the relationship between leadership and followership. This study meta-analyzed 88 research paper on leadership and followership variables for members of domestic organizations from 2000 to 2021. The major findings are as follows: First, The effect size between the followership and the leadership model was found in the order of authentic leadership, ethical leadership, and servant leadership. Although there were many studies that set the variables of transactional leadership and transformational leadership, the effect size with followership was not high. Second, the leadership component factors with the highest followership and effect size was individual consideration, intellectual stimulation, and ideal influence. Through this, it can be seen that the follower-centered approach is effective for leadership with high followership and effect size. This study has practical significance in that it presents a leadership model and component factors that affect followership by analyzing the effect size as an investigation into the study of leadership and followership variable setting conducted in Korea. In addition, it has academic significance in that it suggests the necessity and implications of a relational view of leadership and followership.
Compromiso renal atípico en amiloidosis de cadena ligera
Authors: Kuratomi Nakamura Kenyi , Mejía Andrés Felipe , Valderrama Cometa Luis Alfonso , Casanova Valderrama María Eugenia
Published: September 2022

Introducción: la amiloidosis de cadena ligera (AL) es una entidad desencadenada por la proliferación de un clon de células plasmáticas que genera la acumulación de cadenas ligeras, las cuales se depositan en forma de fibrillas amiloides generando una disfunción orgánica. El compromiso renal generalmente se manifiesta como síndrome nefrótico, con un deterioro lento y progresivo de la función renal que puede llevar a un requerimiento de terapia dialítica.
Objetivo: demostrar el compromiso renal agresivo y subagudo de la amiloidosis sistémica.
Presentación del caso: paciente masculino de 35 años que consulta por malestar general, visión borrosa, mareos y oliguria con elevación de azoados, y que progresó rápidamente hasta el requerimiento de hemodiálisis en aproximadamente tres meses. Asociado se documenta polineuropatía periférica, infiltración cardiaca y ligera elevación de transaminasas. Ante negatividad de estudios de extensión, se logra documentar la presencia histopatológica de depósitos amiloides con inmunofluorescencia positiva para AL. Actualmente, se encuentra recibiendo esquema de quimioterapia con adecuada estabilidad clínica y tolerancia.
Discusión y conclusión: la amiloidosis AL es una entidad infrecuente, con compromiso multiorgánico importante y altas tasas de morbilidad y mortalidad. Se recalca en este caso el compromiso subagudo con requerimiento temprano de terapia dialítica y además se enfatiza la importancia de una sospecha y un diagnóstico oportuno en pacientes con compromiso renal y otras manifestaciones sistémicas.
Embolización transcatéter del injerto renal en pacientes con síndrome de intolerancia: reporte de tres casos en un grupo de trasplantes
Authors: Anaya Taboada Marco , Cabellero-Tovar Dayana , Patiño Jaramillo Nasly , Garcia Lopez Andrea , Girón Luque Fernando
Published: September 2022

Introducción: el síndrome de intolerancia es un proceso inflamatorio que ocurre hasta en un tercio de los pacientes con pérdida del injerto. Cuando no se obtiene una mejoría de los síntomas con el manejo médico, se indica la realización de nefrectomía del riñón trasplantado, sin embargo, este es un procedimiento invasivo que puede estar asociado a mayor morbilidad y mortalidad. Dada la fragilidad de estos pacientes, se plantea la embolización transcatéter del injerto como una alternativa válida y menos invasiva para el tratamiento de este síndrome.
Objetivo: describir el uso de la embolización transcatéter como tratamiento al síndrome de intolerancia del injerto.
Presentación del caso: se reportan tres casos clínicos de pacientes con sintomatología de entre 15 y 20 días de evolución, consistentes en dolor y tumefacción sobre riñón trasplantado y otros signos y síntomas reportados fueron fiebre, hiporexia, pérdida de peso y hematuria macroscópica. Se describe la evolución de los síntomas que en ninguno de los casos expuestos tuvieron mejoría con el ajuste inmunosupresor, descartando en todos los casos etiología infecciosa y estableciéndose así la sospecha síndrome de intolerancia del injerto. Los pacientes fueron manejados con embolización transcatéter de la arteria del riñón trasplantado y el éxito del tratamiento se definió por la resolución de los síntomas.
Discusión y conclusión: entre las primeras 24-48 horas posprocedimiento, los pacientes presentaron una evolución satisfactoria y, finalmente, egreso. La embolización transcatéter del injerto es una alternativa segura a la nefrectomía del trasplante y que es menos invasiva para el tratamiento del síndrome de intolerancia del injerto.
Rechazo crónico mediado por anticuerpos
Authors: Pinto Ramírez Jessica , Celis Conde Sonia , Camargo Salamanca Alejandro , Garcia Lopez Andrea , Girón Luque Fernando
Published: September 2022

Contexto: el rechazo crónico mediado por anticuerpos (cABMR, chronic antibody-mediated rejection) se considera una de las principales causas de disfunción crónica del injerto.
Objetivo: profundizar en la comprensión de los mecanismos que la ocasionan para diseñar tratamientos efectivos, dado que es muy poco lo que se ha avanzado en el tratamiento de esta patología.
Metodología: en esta revisión narrativa de la literatura, presentamos los factores de riesgo relacionados con la disfunción crónica del injerto, haciendo énfasis en la fisiopatología, el diagnóstico y el tratamiento del cABMR.
Resultados: el factor de riesgo más relevante para el desarrollo de disfunción crónica del injerto es el desarrollo de anticuerpos donante específicos (DSA) y ABMR. Para el diagnóstico de cABMR activo, se requieren los criterios de Banff 2017 (los tres deben estar presentes: Evidencia histológica de lesión tisular crónica, evidencia de inflamación actual en el endotelio vascular ocasionada por anticuerpos y evidencia serológica de DSA. El cABMR no tiene un tratamiento efectivo.
Conclusiones: dado que cABMR no tiene un tratamiento efectivo, es importante disminuir la exposición a los factores de riesgo y hacer un diagnóstico y un tratamiento oportuno de los eventos agudos de lesión renal que contribuyen a la progresión de disfunción crónica del injerto.
Procalcitonina sérica como marcador de la función del injerto en el postrasplante renal inmediato
Authors: Ramírez Flores Diana , Andrade-Sierra Jorge , Rojas-Campos Enrique , Evangelista-Carrillo Luis A. , Heredia-Pimentel Alejandro , Montañez-Fernández José Luis , Pazarín-Villaseñor Leonardo , Cerrillos-Gutiérrez José Ignacio
Published: September 2022

Contexto: la procalcitonina (PCT) podría ser útil en la evaluación de la función del injerto renal (IR) en el postrasplante inmediato, ya que sus niveles se incrementan posterior a la elevación de citocinas inflamatorias (IL-6, TNF-?) durante eventos de disfunción renal.
Objetivo: determinar la asociación de la PCT sérica con la función del injerto renal en el periodo postrasplante inmediato.
Metodología: cohorte retrospectiva de septiembre del 2018 a abril del 2019 en la División de Nefrología y Trasplantes, del Centro Médico Nacional de Occidente (CMNO), del Instituto Mexicano del Seguro Social (IMSS). Se incluyeron 62 receptores de trasplante renal de donante vivo (DV) y fallecido (DF) con determinación de PCT en los primeros 7 días del TR y el registro de eventos de disfunción temprana del injerto (DTI), fueron comparados con pacientes sin DTI (sDTI).
Resultados: los receptores con DTI presentaron niveles más altos de PCT (13,90, 3,90, 1,22 ng/mL) comparado con el grupo sin DTI (0,32, 0,31 y 0,22 ng/ml) en los días 1, 3 y 5 respectivamente; p < 0,05.
Conclusiones: la PCT es un marcador biológico asociado a DTI en el postrasplante renal inmediato.
Impacto de un programa de ejercicio físico domiciliario de intensidad leve-moderada sobre calidad de vida, fuerza, resistencia aeróbica, equilibrio y flexibilidad en pacientes adultos mexicanos trasplantados de riñón
Authors: Piñón Martha Jocelyne , Villanueva Carla Paulina , Barrera Karla
Published: September 2022

Contexto: en México, la enfermedad renal crónica presenta un aumento exponencial y el trasplante renal se ha colocado como la mejor opción de tratamiento. A pesar de ello, los receptores de trasplante presentan una menor capacidad funcional y calidad de vida comparándolos con individuos sanos, lo cual se asocia a un estilo de vida sedentario, sumado con los efectos musculoesqueléticos de los inmunosupresores, sin embargo, la investigación es limitada.
Objetivo: evaluar el impacto en calidad de vida, fuerza, resistencia aeróbica, equilibrio y flexibilidad de un programa domiciliario de ejercicio físico de intensidad leve-moderada, en pacientes adultos mexicanos trasplantados de riñón.
Metodología: participaron nueve pacientes (29 ± 5,2 años), a los cuales se les evaluó la fuerza de agarre manual mediante un dinamómetro; la flexibilidad mediante la prueba de “distancia dedos planta” (sit-and-reach test por su nombre en inglés); su agilidad-equilibrio y fuerza en miembro inferior mediante la prueba de “pararse-sentarse”, y “levántate y anda” (sit-to-stand y get-up-and-go por sus nombres en inglés) respectivamente; su actitud cardiorrespiratoria mediante el test de marcha por seis minutos, y su calidad de vida mediante el cuestionario de salud SF36.
Resultados: se mostraron mejoras estadísticamente significativas en dinamometría manual (P 0,005), “distancia dedos planta” (P 0,016), sentarse y pararse (P 0,0011) y test de marcha por seis minutos (P 0,012). En el cuestionario SF36, hubo mejoría en la función física (P 0,03) y salud general (P 0,01), pero no hubo cambios en los análisis de laboratorio y la tasa de filtración glomerular.
Conclusiones: un programa domiciliario de ejercicio combinado de intensidad leve-moderada parece tener un efecto positivo sobre la capacidad funcional y la calidad de vida de los receptores de trasplante renal, sin embargo, es necesaria una mayor investigación para evaluar la adherencia al programa.
Enfermedad de Fabry: un año en tratamiento con migalastat
Authors: Vasquez Gomez Juan Camilo , Tobón Pereira Juan Carlos
Published: September 2022

Introducción: la enfermedad de Fabry (o enfermedad de Anderson-Fabry) es una enfermedad de depósito lisosomal causada por la deficiencia o ausencia de la enzima ?-galactosidasa A, responsable del catabolismo del glicoesfingolípido globotriaosilceramida (Gb3).
Objetivo: en este artículo se expone el caso de un paciente que, a la edad de 64 años con diagnóstico de enfermedad de Fabry, comienza tratamiento con la nueva chaperona oral (migalastat), con evidencia de mejoría en su historia natural de la enfermedad.
Presentación del caso: paciente masculino de 64 años de edad, oriundo de Porto, Portugal, residente en Medellín, Colombia, con enfermedad de Fabry diagnosticada en el año 2010, que fue causada debido a la actividad de la Alfa Galactosidasa A más la mutación fenotípica C.239G>A.
Discusión y conclusión: este reporte de caso ha demostrado la adecuada respuesta del paciente en el manejo con la chaperona farmacológica migalastat. Por lo tanto, un paciente con enfermedad de Fabry, con manifestaciones típicas y una mutación GLA confirmada y que es susceptible de recibir migalastat, tiene esta excelente opción terapéutica con resultados favorables para sus signos y síntomas.
Migalastat (chaperón farmacológico) es un tratamiento oral eficaz y seguro que se traduce en comodidad y beneficios para el paciente y su entorno, lo que permite una mejora significativa de la calidad de vida del paciente.
NAVEGANDO EN LOS CANALES PATAGÓNICOS. ARQUEOLOGÍA DE LOS GRUPOS CANOEROS DEL ARCHIPIÉLAGO DE LOS CHONOS (43°-47°S) Por Omar Reyes Báez Colección Poblamiento Humano de Fuego-Patagonia. Ediciones Universidad de Magallanes. ISBN: 978-956-6147-03-9, 2021. 358 páginas
Authors: Borrero Luis Alberto
Published: September 2022

Navegando en los canales patagónicos es un libro acerca de adaptaciones marítimas en uno de los archipiélagos que configura la fragmentada costa surpatagónica de Chile. La arqueología de estos archipiélagos, muy especialmente el de los Chonos, es muy poco conocida, razón por la que esta obra era muy esperada. El libro incluye tanto una detallada lista de sitios conocidos y explorados en esa región, como una serie de discusiones sobre distintos aspectos de la adaptación canoera a ese particular ambiente. Esta obra complementa y amplía el reciente libro The Settlement of the Chonos Archipelago, Western Patagonia, Chile, del mismo autor, publicado en 2020.
Reflections of interleukin 33, Fetuin A and Cytokeratin 18 in pericardium and plasma in patients with coronary artery disease
Authors: Dikme Reşat , Aydın Mehmet Salih , Temiz Ebru
Published: September 2022

Background: Interleukin 33, Fetuin A and Cytokeratin 18 are
important inflammatory mediators in coronary artery diseases; however,
although the plasma levels of these markers are generally used for the
evaluation, their pericardial levels have not been explored. This study
aims to determine the pericardial behavior of these mediators in
coronary artery diseases and their regression to plasma.
Methods: The gene expression and protein levels of interleukin
33, Fetuin A and Cytokeratin 18 in plasma and pericardial fluid were
investigated in 40 patients undergone coronary bypass surgery.
Results: According to ELISA findings, Interleukin 33 and Fetuin
A protein levels have been found to be significantly increased in
pericardial fluid compared to plasma, p<.05. Although
cytokeratin 18 protein level was also dramatically increased in
pericardial fluid, it was not statistically significant. Gene
expressions of interleukin 33 and Fetuin A were found to be
significantly increased in pericardial fluid compared to plasma,
corroborating the protein levels. Conclusions: Interleukin 33,
Fetuin A and Cytokeratin 18 levels are clinically important and
biomarkers that should be followed. Fluctuations of these biomolecules
suggest that pericardial fluid has a potential to be used as a source of
biomarkers for coronary artery diseases, even if sampling from the
pericardium is not sustainable. Increased Interleukin 33 and Fetuin A
proposes apoptotic machinery activated in the heart tissues of our
patients. Pericardial fluid is an important target for both diagnosis
and treatment because of its proximity and relationship to the heart
tissue.
Predictive Power of Elevated Preoperative HbA1c Levels for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Surgery - Many Questions to be Asked and Many Answers to be Given.
Authors: Budak Ali Baran
Published: September 2022

The authors performed a detailed retrospective analysis of diabetic
patients undergoing isolated coronary artery bypass graft surgery (CABG)
aiming to investigate the association of the preoperative Glycosylated
hemoglobin with occurance of postoperative atrial fibrillation. Altough
statistical analysis showed a weak relationship between HbA1c values of
9.06% or above and PoAF, they concluded that serum level of HbA1c could
not be used as a predictor for the development of PoAF. But there are
many questions to be asked and answers to be found.
Finite-time stability and optimal control for stochastic credit risk contagion model with sentiment
Authors: Shao Yan , Li Ting , Zhang Weiguo , Zhao Wenting
Published: September 2022

Counterparty sentiment and major uncertain factors always affect credit
risk contagion in credit risk transfer (CRT) market. In order to
effectively analyze credit risk contagion, this paper proposes a
stochastic credit risk contagion model considering sentiments, in which
the stochasticity is driven by Lévy process. Based on the Lyapunov
function method, sufficient condition of finite-time stability is
derived. The impacts of counterparty sentiment and Lévy process on
credit risk contagion are analyzed. To effectively control credit risk
contagion, the stochastic credit risk control model is established, and
the optimal control strategy is given by using Pontryagin’s maximum
principle. Numerical simulating results show the correctness and
effectiveness of the theory.
Factors influencing sensitivity of a rapid influenza diagnostic test in a community-based population of kindergarten through 12th grade students: Wisconsin 2015-2020
Authors: Bell Cristalyne , Birstler Jennifer , Goss Maureen , Temte Emily , Barlow Shari , Chen Guanhua , Uzicanin Amra , Temte Jonathan
Published: September 2022

Rapid influenza diagnostic tests (RIDTs) have variable sensitivity. In a
community-based population of kindergarten through 12th grade (K-12)
students, we assessed factors that may influence RIDT performance using
2,368 paired results from Sofia® Influenza A + B fluorescent immunoassay
and reverse transcription polymerase chain reaction (RT-PCR). RIDT
sensitivity and specificity were 76.1% (95% CI: 72.8—79.1) and
97.2% (96.2—97.9), respectively. Factors associated with sensitivity
included runny nose (OR=3.0, p<0.001), nasal congestion (1.59,
p=0.045), days from symptom onset (per day; 0.75; p<0.001),
myalgia (0.61; p=0.014), age (per 5 years; 0.55; p=0.001), and detection
of another virus (0.50; p=0.043). Understanding these factors can aid in
interpreting negative results.
Longitudinal trends in hospital admissions for physical health diseases in survivors of childhood cancer in Western Australia: a population-based linked data study
Authors: Abdalla Tasnim , Ohan Jeneva L. , Walwyn Thomas , White Daniel , Choong Catherine , Bulsara Max , Preen David B.
Published: September 2022

Background. Population-level estimates of hospitalisations for
physical disease in recently treated populations of childhood cancer
survivors are limited. In the Australian context, the long-term effects
of childhood cancer on survivors and the health system are unclear. We
examined the trends in primary hospitalisations for physical disease in
a whole-population cohort of 5-year childhood cancer survivors (CCS)
diagnosed in Western Australia (WA) from 1982-2014. Methods. We
examined hospitalisation records for 2938 CCS and 24 792 matched
‘non-CCS’ controls, discharged from 1987-2019. Andersen-Gill Cox
regression models for recurrent events were used to examine
hospitalisation risk. Mean cumulative counts were used to examine
hospitalisation burden by time since diagnosis and attained age.
Negative binomial regression models were used to examine the annual
percentage change (APC) in hospitalisations. Results. We
identified a higher risk of hospitalisation for all-cause (HR=1.8,
95%CI 1.6-2.0) physical disease in CCS than controls. Compared to
controls, hospitalisation risk was highest for second malignant
neoplasms (HR=13.2, 95%CI 9.9-17.6) and blood diseases (HR=5.6, 95%CI
1.8-17.1) in CCS. Characteristics associated with higher hospitalisation
rates included female gender, diagnosis with malignant bone tumours,
cancer diagnosis age between 5-9 years, multiple childhood cancer
diagnoses, higher comorbidity, high socio-economic deprivation, and
geographic remoteness. The APC in hospitalisations differed between
groups (CCS APC=-3.8%; controls APC=2.4%, p<0.05).
Conclusions. A higher risk of hospitalisation for physical
disease was observed in CCS compared with children not diagnosed with
cancer, with the risk continuing to increase up to 30 years
post-diagnosis. These findings emphasise the need for continued
specialised care and additional research to understand the unmet needs
in this population.
Noninvasive neurally adjusted assisted ventilation as weaning mode in extremely preterm infants: a meta-analysis and systematic review
Authors: Guo Zhaohong , Qiu Youjun , Deng Chun
Published: September 2022

Background: The long duration of IMV for premature infants
connected to adverse clinical complications. It has been proven that
noninvasive ventilation (NIV) improved the weaning process. Noninvasive
neurally adjusted ventilatory assist (NIV-NAVA) is a new type of NIV,
and its effects on weaning are a subject of debate in clinical practice.
To compare NIV-NAVA and conventional NIV as weaning modes in preterm
neonates, this article was preformed. Methods: Cochrane
Library, Embase, PubMed, Scopus, and Web of Science were comprehensively
searched. Published reports were screened and assessed based on
predetermined inclusion and exclusion criteria. The Cochrane Risk of
Bias tool and the Newcastle-Ottawa Scale were used to evaluate the
quality of reports and bias. Review Manager 5.3 was used in the
meta-analysis. Trial sequential analysis (TSA) was used to avoid
false-positive or false-negative conclusions caused by constantly
updated data. Results: Six studies ( n = 265) were
included. Preterm infants who underwent NIV-NAVA had a lower weaning
failure comparing with conventional NIV (risk ratio 0.37, 95%
confidence interval 0.21–0.67, p = 0.001). In TSA the cumulative
Z‑curve crossed monitoring boundary for the benefit of NIV-NAVA
indicated that NIV-NAVA might improve extubation failure. With respect
to the rates of related adverse clinical events, there was no
statistically significant difference between the NIV-NAVA group and the
conventional NIV group in forest plots. Conclusion: The current
meta-analysis suggests that NIV-NAVA may reduce the rate of extubation
failure compared to conventional NIV.
A first-in-human study of the anti-inflammatory profibrinolytic TMS-007, an SMTP family triprenyl phenol
Authors: Moritoyo Takashi , Nishimura Naoko , Hasegawa Keiko , Shinya Ishii , Kirihara Kenji , Takata Munenori , Kishi-Svensson Akiko , Umeda-Kameyama Yumi , Kawarasaki Shuichi , Ihara Ryoko , Sakanaka Chie , Wakabayashi Yurie , Niizuma Kuniyasu , Tominaga Teiji , Yamazaki Tsutomu , Hasumi Keiji
Published: September 2022

Background: TMS-007, an SMTP family member, modulates plasminogen
conformation and enhances plasminogen-fibrin binding, leading to
promotion of endogenous fibrinolysis. Its anti-inflammatory action
mediated by soluble epoxide hydrolase inhibition contributes to the
efficacy. Evidence suggests that TMS-007 can effectively treat
experimental thrombotic and embolic strokes with a wide time window
while reducing hemorrhagic transformation. Aims: To evaluate the safety,
pharmacokinetics, and pharmacodynamics of TMS-007 in healthy volunteers.
Methods: A randomized, placebo-controlled, double blind, dose-escalation
study, administered as a single intravenous infusion of TMS-007 in
cohorts of healthy male Japanese subjects. There were 6 cohorts planned,
but 5 were completed. In each cohort (n = 8), individuals were
randomized to receive one of 5 doses of TMS-007 (3, 15, 60, 180, or 360
mg; n = 6) or placebo (n = 2). Results: TMS-007 was
generally well-tolerated, and no serious adverse events attributed to
the drug. A linear dose-dependency was observed for plasma TMS-007
levels. No symptoms of bleeding were observed in brain MRI analysis, and
no bleeding-related responses in laboratory testing were found. The
plasma levels of the coagulation factor fibrinogen and the
anti-fibrinolysis factor 2-antiplasmin levels were unchanged after the
TMS-007 dosing. A slight increase in the plasma level of
plasmin-α-antiplasmin complex, an index of plasmin
formation, was observed in some subjects who received 360 mg of TMS-007
(≈ 6 mg kg). Conclusions: TMS-007 is generally
well-tolerated and exhibits favorable pharmacokinetic profiles that
warrant further clinical development.
The time-harmonic electromagnetic wave scattering by a bi-periodic elastic body
Authors: Wei Changkun , Zhu Tielei , Yang Jiaqing
Published: September 2022

This paper concentrates on an interaction scattering problem between the
time-harmonic electromagnetic waves and an unbounded periodic elastic
medium. The uniqueness results of the interaction problem are
established for small frequencies or all frequencies except a discrete
set in both the absorbing and non-absorbing medium, and then the
existence of solutions is derived by the classical Fredholm alternative.
The perfectly matched layer (PML) method is proposed to truncate the
unbounded scattering domain to a bounded computational domain. We prove
the well-posedness of the solution for the truncated PML problem, where
a homogeneous boundary condition is imposed on the outer boundary of the
PML. The exponential convergence of the PML method is established in
terms of the thickness and parameters of the PML. The proof is based on
the PML extension and the exponential decay properties of the modified
fundamental solution.
Spatial phenotypic variability is higher between island than mainland populations worldwide
Authors: Csergő Anna , Healy Kevin , Baudraz Maude , Kelly David , O’Connell Darren , Marcaigh Fionn Ó , Smith Annabel , Villellas Jesus , White Cian , Yang Qiang , Buckley Yvonne
Published: September 2022

Spatial isolation is a key driver of population-level variability in
traits and genotypes worldwide. While geographical distance between
populations can determine isolation, organisms may face additional
barriers when dispersing between suitable habitat patches. Despite the
predicted universal nature of factors underlying isolation, global
comparisons of isolation effects across taxa and geographic systems are
few. We assessed the strength of isolation due to geographic and
macroclimatic distance across island and mainland systems, comparing
published measurements of phenotypic traits and neutral genetic
diversity for 1832 populations of plants and animals worldwide. As
expected, phenotypic differentiation was higher between islands than
mainland populations. However, geographic and macroclimatic distances
had weak effects on phenotypic variability and neutral genetic diversity
in both systems. Our results show that macroecological models of
population variability should consider the spatial structure of
populations in addition to the commonly employed predictors of
environmental conditions or geographic distances between populations.
Comparative Efficacy of Three Surgical Modalities for Recurrent Respiratory Papillomatosis
Authors: Liu SiWei , Wang Jiaqi , Yu Jin-Chao , He Changding , Huang Fang , Shao Jun
Published: September 2022

Abstract Background：Recurrent respiratory papillomatosis (RRP) is
recurring benign papillomatous lesions which still relies on repeated
surgical treatment. However, there is no guidelines of surgical
technique nowadays. Objectives: This retrospective cohort study aims to
obtain a better understanding of RRP, and select the best surgical
modality for RRP among microdebrider, CO2 laser and KTP laser. Study
design: Retrospective cohort study. Methods: Medical records of 112 RRP
patients treated at EYE&ENT Hospital of Fudan University from 2018 to
2021 were reviewed, with at least 6-month follow-up. Three treatment
subgroups(microdebrider, CO2 laser and KTP laser) were analyzed within
AO-RRP and JO-RRP populations respectively. Results: 112 patients (39
JO-RRP and 72 AO-RRP) and a total of 353 surgical procedures were
included. Jo-RRP group had higher Derkay anatomical
score(p<0.05), lower percentage of dysplasia and an earlier
trend in recurrence(p<0.05) than Ao-RRP group. There were no
significant differences among three surgical modalities on median
treatment intervals(MTI) or survival curves(p>0.05), with
the Jo-RRP MTI of the microdebrider(92.5[47.3~200]),
CO2 laser(140[70~255]), KTP
laser(90[62.3~221.3]), and Ao-RRP
microdebrider(267.50[152.5,449.5]), CO2
laser(247.5[145.5,474.7]), KTP laser(107.5[68.3,330.5]).
Conclusion and Significance: The Jo-RRP patients have more concomitant
invasiveness, but less dysplasia than AO-RRP patients. Three surgical
modalities appeare to be equally effective in management of Jo-RRP or
AO-RRP. Key Words: Papillomatosis, surgery, treatment, recurrence,
efficacy.
An externally validated model to predict prolonged induction of labor with an unfavorable cervix: a retrospective cohort study
Authors: Kawakita Tetsuya , Saeed Haleema , Huang Jim
Published: September 2022

Objective: To develop and externally validate a prediction model to
calculate the likelihood of prolonged induction of labor (induction
start to delivery time >36 hours). Design: A retrospective
cohort study Setting: Academic centers in the United States Population:
Nulliparous women with singleton pregnancies and vertex presentation at
term who underwent induction of labor and had a vaginal delivery at a
single academic center. Methods: Analyses were limited to women with an
unfavorable cervix. A backward stepwise logistic regression analysis was
used to identify the factors associated with prolonged induction of
labor. The final model was validated using an external dataset of the
Consortium on Safe Labor after applying the same inclusion and exclusion
criteria. We developed a receiver observer characteristic curve with
area under the curve (AUC). Main outcomes of measures: Prolonged
induction of labor Results: Of 2,118 women, 364 (17%) had prolonged
induction of labor. Factors associated with prolonged induction of labor
included body mass index, hypertension, fetal conditions, and epidural.
Factors including younger maternal age, prelabor rupture of membranes,
and a more favorable simplified Bishop score were associated with a
decreased likelihood of prolonged induction of labor. In the external
validation cohort, 4,418 women were analyzed, of whom 188 (4%) had
prolonged induction of labor. The AUC of the final model was 0.76
(95%CI 0.73-0.80) for the external validation cohort. The online
calculator was created and is available at
https://medstarapps.org/obstetricriskcalculator. Conclusion: Our
externally validated model was efficient in predicting prolonged
induction of labor with an unfavorable cervix.
In confinibus Turcorum
Authors: Salihović Davor
Published: September 2022

The paper discusses the backgrounds and careers of several lesser-known officials who occupied various positions along the Hungarian-Ottoman frontier during the reign of King Matthias Corvinus of Hungary (r. 1458-1490). By examining their biographies and their place within the ruling elite of Corvinus’s Hungary, the study moreover elucidates how changes in King Matthias’s authority in the borderlands were reflected in the changes in his personnel policies, showing that the king gradually gained more control over his southern lands through a growing network of loyal retainers. The latter, moreover, successfully replaced the vestiges of older regimes – whose representatives often stood in opposition to royal politics – thus allowing the introduction of greater royal control.
Žumberački uskoci i potraga Dušana Preradovića za obiteljskom prošlošću
Authors: Matić Tomislav
Published: September 2022

Rad istražuje isprave o obiteljima žumberačkih uskoka prezimena Preradović koje je pretraživanjem raznih arhiva pronašao Dušan Preradović, sin pjesnika Petra Preradovića, te pisma koja je slao povjesničaru Emiliju Laszowskom. Na temelju tih dokumenata rekonstruira se potraga Dušana Preradovića za poviješću njegove obitelji, kao i konstrukcija obiteljske tradicije i identiteta na temelju njegovih pronalazaka. Dušan arhive nije pretraživao osobno, nego je za to angažirao stručnjake poput Hermanna Ignaza Bidermanna i Emilija Laszowskog, a opterećivalo ga je i nedovoljno poznavanje historiografskoga rada. Vjerojatno ga je upravo ta potraga ponukala da poveća svoje poznavanje historiografije. Svoje je nalaze o obiteljskoj prošlosti objavio 1903. u časopisu Vitezović. Prilikom potrage naišao je na više obitelji prezimena Preradović, ali se fokusirao na onu žumberačkoga uskoka Ivana Preradovića jer je na temelju njegove grbovnice, izdane 1626., njegov otac, i on sâm, imao pravo na plemićki status. Pritom je bio svjestan da je njegova obiteljska veza s Ivanom nedovoljno dokazana, pa je nastojao pronaći još isprava, a potragu je proširio ispitivanjem osoba za koje je smatrao da bi mogle znati više o prošlosti Žumberka, poput grkokatoličkoga župnika Jovana Hranilovića. Iako nije uspio pronaći sigurne dokaze o obiteljskoj vezi s Ivanom Preradovićem, on i njegova obitelj smatrali su ga svojim pretkom.
Privatna knjižnica zadarskoga učenjaka Šimuna Ljubavca i kultura čitanja u jednom dalmatinskom gradu 17. stoljeća
Authors: Novosel Filip
Published: September 2022

Višestoljetne veze dviju jadranskih obala rezultirale su razmjenom iskustava na brojnim razinama, a kulturna djelatnost u tom je smislu svakako nezanemariva. U ovom se radu kroz specifičan aspekt konzumiranja kulture u gradu Zadru, na temelju čitalačkih navika jednoga od njegovih istaknutih stanovnika, gradskoga plemića i učenjaka Šimuna Ljubavca (1608. – 1663.), prikazuju intelektualne preokupacije društvenih elita na prostoru istočnoga Jadrana. Analizom inventara Ljubavčevih dobara, koji uz ostalo otkriva i njegovu bogatu privatnu knjižnicu, čitalački afiniteti ovoga učenjaka poslužit će kao paradigma za bolje poznavanje opće kulture čitanja na istočnojadranskom prostoru i definiranje njegove pozicije na relaciji kulturnih središta i periferija onovremenoga Sredozemlja.
The Portfolio Diet and Incident Type 2 Diabetes: Findings From the Women’s Health Initiative Prospective Cohort Study
Authors: Glenn Andrea J. , Li Jie , Lo Kenneth , Jenkins David J.A. , Boucher Beatrice A. , Hanley Anthony J. , Kendall Cyril W.C. , Shadyab Aladdin H. , Tinker Lesley F. , Chessler Steven D. , Howard Barbara V. , Liu Simin , Sievenpiper John L.
Published: September 2022

OBJECTIVE

A plant-based dietary pattern, the Portfolio Diet, has been shown to lower LDL cholesterol and other cardiovascular disease risk factors. However, no study has evaluated the association of this diet with incident type 2 diabetes.

RESEARCH DESIGN AND METHODS

This analysis included 145,299 postmenopausal women free of diabetes at baseline in the Women’s Health Initiative (WHI) Clinical Trials and Observational Study from 1993 to 2021. Adherence to the diet was assessed with a score based on six components (high in plant protein [soy and pulses], nuts, viscous fiber, plant sterols, and monounsaturated fat and low in saturated fat and cholesterol) determined from a validated food-frequency questionnaire. We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95% CIs of the association of the Portfolio Diet, alongside the Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets, with incident type 2 diabetes, with adjustment for potential confounders.

RESULTS

Over a mean follow-up of 16.0 years, 13,943 cases of incident type 2 diabetes were identified. In comparisons of the highest with the lowest quintiles of adherence, the HRs for risk of incident type 2 diabetes were 0.77 (95% CI 0.72, 0.82) for the Portfolio Diet, 0.69 (0.64, 0.73) for the DASH diet, and 0.78 (0.74, 0.83) for the Mediterranean diet. These findings were attenuated by 10% after additional adjustment for BMI.

CONCLUSIONS

Greater adherence to the plant-predominant Portfolio, DASH, and Mediterranean diets was prospectively associated with lower risk of type 2 diabetes in postmenopausal women.
Prescription Patterns of Cardiovascular and Kidney Protective Therapies Among Patients with Type 2 Diabetes and Chronic Kidney Disease
Authors: Lamprea-Montealegre Julio A. , Madden Erin , Tummalapalli Sri Lekha , Chu Chi D. , Peralta Carmen A. , Du Yuxian , Singh Rakesh , Kong Sheldon X. , Tuot Delphine S. , Shlipak Michael G , M. Estrella Michelle
Published: September 2022

  

Objective

To assess the prevalence and correlates of prescription of sodium-glucose co-transporter-2-inhibitors (SGLT2i) and/or glucagon-like peptide-1-receptor agonists (GLP1-RA) in persons with type 2 diabetes mellitus (T2DM) with and without chronic kidney disease (CKD). 

Methods

Cross-sectional analyses of SGLT2i and GLP1-RA prescriptions from January 1st, 2019, to December 31st, 2020, in the Veterans Health Administration System. The likelihood of prescriptions was examined by presence or absence of CKD and by predicted risks of atherosclerotic cardiovascular disease (ASCVD) and end-stage kidney disease (ESKD). 

Results

Of 1,197,880 adults with T2DM, SGLT2is and GLP1-RAs were prescribed to 11% and 8% of patients overall, and to 12% and 10% of those with concomitant CKD, respectively. In adjusted models, patients with severe albuminuria were less likely to be prescribed SGLT2i or GLP1-RA versus non-albuminuric patients with CKD: OR (95% CI) = 0.91 (0.89, 0.93) and 0.97 (0.94, 1.00), respectively. Patients with 10-year ASCVD risk >20% (versus <5%), had lower odds of SGLT2i use (OR=0.55 (0.52, 0.59)) and GLP1-RA prescription (OR=0.54 (0.50, 0.59)). A 5-year ESKD risk >5%, compared with <1%, were associated with lower likelihood of SGLT2i prescription (OR=0.63 (0.59, 0.67)) but higher likelihood of GLP1-RA prescription (OR=1.53 (1.46, 1.61)).

Conclusions

Among a large cohort of patients with T2DM, prescription of SGLT2i and GLP1-RA was low in those with CKD. We observed a “risk-treatment paradox”, whereby patients with higher risk of adverse outcomes were less likely to receive these therapies. 
Design and Studying the Effect of Inner Bore Diameter of Unipolar Lens
Authors: AL-Salih Rafa Y. J. , AL-Janan Mohammed K. A.
Published: September 2022

This work investigated the development of magnetic and optical properties and the invention of a previously unused lens. Many new designs have been suggested for a unipolar magnetic lens based on changing the width of the inner bore and fixing the other geometrical parameters of the lens to improve the performance of unipolar magnetic lenses. The investigation of a study of each design included the calculation of its axial magnetic field the magnetization of the lens in addition to the magnetic flux density using Finite Element Method (FEM). it was found that the best magnetizing properties, the highest value of magnetic flux and the lowest value of band width of the axial magnetic field strength have been obtained when the width of the inner cavity was (55 mm). The effect of current density on the optical properties has been also studied, and it was found that the optical properties have been improved also, and the chromatic and spherical aberration values have decreased significantly. Thus, the lens (55 mm) was chosen as the best design among the proposed designs.
Using Evolving Algorithm with Distance Indicator for Solving Different Non-linear Optimization Problems
Authors: Ayad Saja , T. Abbas Iraq
Published: September 2022

In this paper, we have relied on the dominant control system as an important tool in building the group of leaders because it allows leaders to contain less dense areas, avoid local areas and produce a more compact and diverse Pareto front. Nine standard nonlinear functions yielded this result. MaBAT/R2 appears to be more efficient than MOEAD, NSGAII, MPSOD, and SPEA2. MATLAB was used to generate all the results of the proposed method and other methods in the same field of work.
Academic anatomy of the memory of “The City of Russian Glory”. Review of Volkov, E.V., N.S. Zhuravleva, and I.V. Sibiryakov. “Leningrada chernomorskii brat”: Sevastopol' v sovetskoi kul'turnoi pamyati: monografiya [“Leningrad’s Black Sea brother”: Sevastopol in Soviet cultural memory]. Chelyabinsk: Izdatel'skii tsentr YuUrGU, 2021. (In Russian)
Authors: Popov Aleksei D.
Published: September 2022

The monograph under review is a successful attempt to reconstruct the place of Sevastopol in the cultural memory of the Soviet period by means of in-depth analysis of the system of discourse related to the history of this city, “places of memory,” and commemorative practices (with special attention to the celebration of historical anniversaries). The authors managed to create a holistic image of how the main stages in the history of the “City of Russian Glory” together with the related narratives and personalities were included in the general context of the Soviet politics of history and are presented in the collective consciousness. To achieve the purpose of the study, they gave a detailed description of numerous memorial constructions, museum expositions, works of fine art, musical works, scientific and popular-science literature, memoirs and fiction, theatrical productions, documentaries and feature films – all the things that determined general visual and discourse content of the collective memory of the past in the context of the 20th century. The monograph under review is of great significance for Russian memory studies and is recommended to those who are interested in the history of Sevastopol and engaged in memory studies, new cultural history, symbolic policy, and discourse studies. At the same time, despite the variety of the topics raised and the depth of the analysis conducted, there remains a broad heuristic field for new studies devoted to the legendary “City of Russian Glory” in domestic memorial culture and historical memory.
Assessment of the place and role of student movement in the transformation of socio-political system of Russia in the early 20th century (based on the materials of the journal Osvobozhdenie)
Authors: Smirnov Ivan М. , Dryablov Sergei A.
Published: September 2022

The issue of involving young people in political movement in the process of purposeful activities of political parties remains one of the understudied problems in the history of Russian liberalism and its political and legal thought up to the present. The article analyzes domestic liberal theorists’ search for an answer to the question concerning reasons for the politicization of the youth, primarily the student movement in Russia, which was partially reflected in the publications of the journal Osvobozhdenie [Liberation]. It is noted that two groups of factors are distinguished, those of general nature associated with the shortcomings of the social system as a whole and more specific factors related to the concrete youth policy of the state. The authors pay attention to how the liberals who wrote to the journal determined the place of the youth movement in the process of social transformation. Identification of their positions appears important and necessary in order to answer the question, which the liberal parties and party leaders faced in full growth during the period of the revolution, whether it was possible and reasonable to involve young people in revolutionary processes and in socio-political activities of party organizations. For the liberals, this issue was important due to the significant reflection of the Russian intelligentsia in relation to young people, their youthful radicalism. The article is based on the materials of the pre-parliamentary period in the history of Russian liberalism and covers the years from 1902 to 1905.
On the separation of Neo-Populists and the formation of the Popular Socialist Party
Authors: Protasova Olga L.
Published: September 2022

The article is devoted to the origins of the Popular Socialist Party, which is a question that has not been given a clear answer by modern historiography yet. It considers events and discussions during the founding congress of the Socialist Revolutionary Party (December 25, 1905 – January 2, 1906), where the final separation between Neo-Populists took place. The author identifies and analyses the main contradictions between the left-wing and right-wing Neo-Populists related to the party program and its tactics, which became especially acute during the congress. Main differences in the attitudes towards the illegal methods of political struggle that were accepted by the Socialist-Revolutionaries and rejected by the future Popular Socialists are pointed out. The author also analyses their program differences regarding the solution of the agrarian question in Russia: socialization among the Socialist-Revolutionaries and nationalization among the moderate Populists. The socio-psychological factors that hindered any constructive dialogue between the Socialist-Revolutionaries and the Russkoe bogatstvo group are revealed. The grounds for classifying the moderate Populists in the early 20th century as part of the Socialist Revolutionary community and the arguments in favor of the independent formation of the Popular Socialist Party are presented.