bluuebunny/crossref_metadata_2025 huggingface dataset:
Lymph Node Yield in Gastrointestinal Cancer Surgery With or Without Prior Neoadjuvant Therapy: Protocol for a Systematic Review and Meta-analysis
Authors: Ronellenfitsch Ulrich , Mathis Nika , Friedrichs Juliane , Kleeff Jörg
Published: March 2022

Background

Lymph node yield is the number of lymph nodes retrieved during oncological resection and histopathologically identified in the resection specimen. It is an important surrogate parameter for assessing the oncological radicality of the resection of gastrointestinal carcinomas, as well as a prognostic factor in these diseases. It remains unclear if and to what extent neoadjuvant chemotherapy, radiotherapy, or chemoradiotherapy, which have become established treatments for carcinoma of the esophagus, stomach, and rectum and are increasingly used in pancreatic carcinoma, affect the lymph node yield.

Objective

This systematic review with meta-analysis is conducted with the aim of summarizing the available evidence regarding the lymph node yield, an oncological surrogate marker, in patients with gastrointestinal carcinomas undergoing surgery after neoadjuvant therapy compared to those undergoing surgery without neoadjuvant therapy.

Methods

Randomized and nonrandomized studies comparing oncological resection of esophageal, stomach, pancreatic, and rectal carcinoma with and without prior neoadjuvant therapy are eligible for inclusion regardless of study design. Publications will be identified with a defined search strategy in 2 electronic databases: PubMed and Cochrane Library. The primary endpoint of the analysis is the number of lymph nodes identified in the resected specimen. Secondary endpoints include the number of harvested metastatic lymph nodes, operation time, postoperative complications, pathological TNM staging, and overall and recurrence-free survival time. Using suitable statistical methods, the endpoints between patients with and without neoadjuvant therapy, as well as in defined subgroups (neoadjuvant chemotherapy, radiotherapy, or chemoradiotherapy; and patients with esophageal, gastric, pancreatic, or rectal cancer), will be compared.

Results

The literature search and data collection started in October 2021. Results are expected to be published in mid-2022.

Conclusions

This meta-analysis will provide the most up-to-date and complete summary of the evidence on an association between neoadjuvant therapy and lymph node yield in gastrointestinal cancer surgery. The underlying hypothesis is that neoadjuvant therapy decreases the number and size of lymph nodes through lymphocyte depletion and radiation-induced fibrosis, thus leading to a lower possible lymph node yield. The findings of the meta-analysis will show if this hypothesis is supported by evidence.

Trial Registration

PROSPERO CRD218459; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021218459

International Registered Report Identifier (IRRID)

DERR1-10.2196/35243
Perception of Web-Based Didactic Activities During the COVID-19 Pandemic Among Anesthesia Residents: Pilot Questionnaire Study (Preprint)
Authors: Nozari Ala , Mukerji Shivali , Lok Ling-Ling , Gu Qingrou , Buhl Lauren , Jain Sanjay , Ortega Rafael
Published: March 2022

BACKGROUND

Physical and social distancing recommendations aimed at limiting exposure during the COVID-19 pandemic have forced residency programs to increasingly rely on videoconferencing and web-based resources.

OBJECTIVE

In this pilot study, we aimed to explore the effects of the COVID-19 pandemic on residency training experience, and to delineate the perceived barriers to the successful implementation of web-based medical education.

METHODS

A 19-item survey was compiled and distributed electronically using Qualtrics. This anonymous survey included information on the training level of each resident, their participation in formal didactics before and during the pandemic, and their perception of the ease and limitations of virtual didactics. The resident’s opinions on specific educational resources were assessed, and the effectiveness of new delivery methods on resident engagement and learning was examined.

RESULTS

Thirty anesthesiology residents were surveyed, 19 of whom agreed to participate in the pilot study. One participant with incomplete responses was excluded, yielding a final cohort of 18 respondents. Most residents (56%, 10/18) reported that the COVID-19 pandemic negatively affected their residency training. The time spent on didactic training and independent studies was, nevertheless, not affected by the pandemic for 90% (16/18) of respondents. Nonetheless, 72% (13/18) of residents were less engaged during virtual lectures in comparison to in-person didactics. Important limitations included distraction from the physical environment (67%, 12/18), internet instability (67%, 12/18), less obligation to participate (44%, 8/18), technical difficulty and unmuted microphones (33%, 6/18, each), and people speaking over each other (28%, 5/18). Despite these limitations, most residents stated that they would like to keep a combination of virtual didactics including live Zoom lectures (56%, 10/18), prerecorded web didactics (56%, 10/18), and virtual ground rounds via Zoom (50%, 9/18) as the “new normal.”

CONCLUSIONS

Despite important limitations listed in this report, anesthesia residents would like to keep a combination of virtual lectures and presentations as the new normal after the COVID-19 pandemic.
Associations of maternal and paternal parenting practices with children’s fruit/vegetable intake and physical activity: Preliminary findings from an ecological momentary study (Preprint)
Authors: Lopez Nanette , Lai Mark H-C , Yang Chih-Hsiang , Dunton Genevieve Fridlund , Belcher Britni Ryan
Published: March 2022

BACKGROUND

Childhood obesity prevention interventions routinely focus on changing maternal parenting practices. Failure to assess how fathers’ weight-related (i.e., diet and physical activity) parenting practices contribute to children’s energy-balance behaviors limits the understanding of their paternal role within the family. Examining the independent and interacting effects of fathers’ and mothers’ weight-related parenting practices on children’s diet and physical activity addresses this important research gap.

OBJECTIVE

The current study used ecological momentary assessment (EMA) to investigate the within-subject (WS) and between-subject (BS) independent and interactive effects of maternal and paternal (1) encouragement to eat and preparation of fruits and vegetables (F/V) and (2) encouragement of and taking their child to be physically active on their child’s self-reported F/V intake and physical activity engagement.

METHODS

Participants included mother-father-child triads (n=22 triads, n=205-213 prompts/occasions) in the Mothers and Their Children’s Health Study and the University of Southern California Fathers Study. Simultaneously, mothers and fathers (mean ages=44.2 + 5.6 and 45.2+ 8.1, respectively), and their children (mean age=12.0 + 0.7) completed up to 8 randomly prompted EMA surveys per day on separate smartphones for 7 days. At each prompt, mothers and fathers each reported whether they did the following in the past 2 hours: (1) encouraged their child to eat F/V, (2) prepared F/V for their child, (3) encouraged their child to be physically active, and (4) took their child to be physically active. Children self-reported whether they consumed F/V or were physically active in the past two hours.

RESULTS

Results from Bayesian multilevel logistic models (all in log odd units) indicated that at the WS level, greater maternal encouragement (OR=2.01, CI=0.07-5.34) of eating F/V was associated with greater child report of eating F/V, but paternal encouragement (OR=0.84, CI=-3.71-6.58) showed no additional effects above and beyond maternal encouragement. Additionally, greater than usual paternal encouragement (OR=2.0 CI=0.08-5.24) and maternal encouragement (OR=2.58, CI=0.43-6.41) of physical activity had significant independent additive effects and were associated with greater child report of physical activity. No other WS or BS associations, nor interactive effects were significant.

CONCLUSIONS

Findings from this study suggest that fathers play a role in supporting their children’s physical activity compared to their intake of F/V. Future EMA studies should recruit larger samples to evaluate the interacting roles of mothers’ and fathers’ weight-related parenting practices on child’s obesogenic behaviors.
Antioxidant and Antihyperlipidemic Effect of Purple Sweet Potato Leaf Extract (Ipomoea batatas L.) and Red Yeast Rice Combination In Hypercholesterol Rats
Authors: Mahfudh Nurkhasanah , Mantali Muhammad Fathurrachman , Sulistyani Nanik
Published: March 2022

Hyperlipidemia is a condition of lipid such as cholesterol and triglycerides in the blood are high, which is the cause of other diseases. This condition also causes an increase in free radicals resulting in oxidative stress. Purple sweet potato leaves and red yeast rice have been reported to have antihyperlipidemic and antioxidant activity in several studies. This study aimed to examine the effect of the combination of purple sweet potato leaves extract and red yeast rice on cholesterol and triglyceride levels as well as MDA levels and GPx activity on rats induced by a high-fat diet. Experimental animals were randomly divided into 6 groups of 5 mice each: group 1 being the normal group; group 2 positive control; group 3 negative control; group 4 purple sweet potato leaf extract 400 mg/kg BW; group 5 red yeast rice 40 mg/kg BW; group 6 combination of purple sweet potato leaf extract 360 mg/kg BW and red yeast rice 40 mg/kg BW. Rats were treated with high-fat feed for 28 days, on day 15-28 were given oral preparations. At the end of the study, all rats were blood drawn to measure cholesterol and triglyceride levels, then rats were sacrificed and the liver was taken to measure MDA and glutathione peroxidase levels. The administration of purple sweet potato leaf extract, red yeast rice, and their combination significantly (p<0,05) reduced cholesterol, triglyceride, and MDA levels, and increased GPx activity, with the best effect in the combination group. This finding showed that the combination of purple sweet potato leaf extract and red yeast rice had antihyperlipidemic and antioxidant activity in hypercholesterol rats.
Effect of Pharmacist Interventions on Medication Adherence to Capecitabine in Cancer Patients: A Systematic Review
Authors: Puspitasari Atika Wahyu , Kristina Susi Ari , Satibi  , Prabandari Yayi Suryo
Published: March 2022

Oral chemotherapy poses challenges regarding patient medication adherence. Pharmacists play a vital role in supporting medication adherence to achieve the effectiveness of therapy. This review aimed to evaluate the impact of pharmacist interventions on medication adherence in patients with cancer taking capecitabine. The literature was systematically reviewed using Scopus, ScienceDirect, Sage Journal, Springer Link, PubMed, and Google Scholar. Key text words included “adherence, pharmacist intervention, capecitabine, oral chemotherapy, and cancer.” We collected original articles published from January 2010 to June 2021 in English that reported pharmacist interventions to enhance capecitabine adherence in adult patients with cancer and assessed adherence rates pre- and post-intervention. Two independent researchers extracted data relevant to inclusion criteria and determined the methodological quality of studies using the Joanna Briggs Institute Critical Appraisal Checklist Tools. A total of 4179 articles were retrieved, of which five were eligible for review. The most common pharmacist intervention strategy was a combination of patient education, with oral and written information provided. Components of patient education were the characteristics of capecitabine, including its mechanism of action, side effects, and their management; current therapeutic regimen; importance of adherence; and risk of non-adherence. Pharmacist interventions provide beneficial impacts on medication adherence, beliefs about medication, and tolerability of side effects. The findings suggest that pharmacist interventions support medication adherence improvement and highlight the role of pharmacist interventions in pharmaceutical oncology care services. Further studies are necessary to assess pharmacist interventions’ long-term effects and clinical outcomes.
3 Co-TEAM: A logic model for pharmacy health coaching among substance use disorders patients
Authors: Haryono Alexxander , Ika Puspitasari  , Susi Ari Kristina  , Cecep Sugeng Kristanto  , Erna Prihandiwati
Published: March 2022

ABSTRACT

Background: Pharmacy health coaching on various chronic diseases has been widely used with promising results. Drug addiction is a chronic disease, however, the intervention model of pharmacy health coaching in these patients has not been previously reported.

Objective: Developing a logic model for pharmacy health coaching among substance use disorders patients that can be used by community pharmacists as a tool to support development, innovation, monitoring, and evaluating the performance of pharmacy health coaching.

Methods: A logic model used to develop an intervention model of pharmacy health coaching following a process consisting of four steps: (1) a literature review to identify key values, scope, delivery & tools, the content of the session, and competencies for pharmacy health coaching; (2) focus groups discussion (FGD) to obtain information from specific sources and discuss the results of the literature review; (3) developing a logic model based on the finding from steps 1 and 2; and (4) FGD to discuss and fine-tune the model.

Results: A logic model was successfully constructed and generated 3 Co-TEAM models for pharmacy health coaching among substance use disorders patients. The 3 Co-TEAM consists of communication, collaboration, consultation, training, education, attitude, and motivational interviewing.

Conclusion: The 3 Co-TEAM model for pharmacy health coaching provides steps to implement this service in an objective, organized and comprehensive manner. The proposed model can function as a tool that provides guidance and reference for pharmacists in the process of implementing pharmacy health coaching among substance use disorders patients and collaborating with other health professionals.

 

Keywords: logic model, pharmacy health coaching, substance use disorders, pharmaceutical services, patient-centered care
Application of Ftir-Atr Spectroscopy in Combination With Multivariate Analysis to Analyse Synthetic Drugs Adulterant in Ternary Mixtures of Herbal Medicine Products
Authors: Fatmarahmi Dharmastuti Cahya , Susidarti Ratna Asmah , Swasono Respati Tri , Rohman Abdul
Published: March 2022

To against the increasing number of adulteration reports in herbal medicine products in Indonesia, specifically Jamu in powder dosage form, a rapid, efficient, inexpensive method is required. This study was aimed to develop an approach for quantification and classification of an unadulterated herbal medicine product with synthetic drug (prednisone and metamizole) by combining FTIR Spectroscopy and multivariate calibration (PLSR and PCR) as well as discriminant analysis (DA). The spectra data of three individual types of reducing herbal pain products were scanned and collected by FTIR-ATR in the mid-infrared region and further analyzed by two multivariate calibrations to exhibit the optimum mode for quantification analysis of each sample reducing herbal pain product. Based on statistical parameter value, PCR analysis of each model demonstrated the highest value of R2 in both calibration and validation and the lowest value of root mean square of calibration (RMSEC) and root mean square of prediction (RMSEP). The discriminant analysis (DA) was also performed in this study to classify pure reducing pain herbal medicine products without any drugs contaminant and adulterated with synthetic drugs. The outcome of DA was shown by Cooman’s plot and DA could discriminate adulterated and unadulterated reducing pain herbal medicine products with 100% accuracy level. FTIR-ATR spectroscopy in the mid-infrared region coupled with chemometrics could be a potential analytical technique to detect synthetic drugs contaminant in herbal products.
The Javanese Diaspora in New Caledonia reflected in Ama Bastien’s Le Rêve Accompli de Bandung à Noumea and Marc Bouan’s L’Echarpe et le Kriss
Authors: Hayuningsih Arifah Arum Candra
Published: March 2022

New Caledonia is a French Overseas Territorywhose lit erary works do not take the “center stage” in Francophone literature. In particular, the Javanese diasporic community in this archipelago has received relatively little attention from researchers, with past studies largely focusing on Javanese indentured laborers in Suriname, instead. This research examined the autobiographical novels of two New Caledonian writers, Le rêve accompli de Bandung à Nouméa by Ama Bastien and L’écharpe et le kriss by Marc Bouan. These writers belong to the second generation of Javanese immigrants, whose parents came to New Caledonia at the beginning of the 20th century under the indentured laborer scheme. The analysis employed diasporic and cultural identity as its theoretical framework, along with Steven Tötösy de Zepetnek’s comparative cultural studies method. The results explicate the way in which these novels embody the establishment of identity in the Javanese diaspora in New Caledonia. They also demonstrate how the contestation of identity and memory is inextricably linked to the problems of the Javanese diasporic communities. These findings should contribute to and encourage the further study of diasporic communities related to Southeast Asian indentured labor.
The Capacity of Posyandu Cadres Through Complementary Food for Children by Training
Authors: Sudiarti Trini , Amelia Tiara , Hasanah Indah Jamiatun
Published: April 2022

Nutritionist from Center of Public Health Beji stated that there are still many cadres who have not participated in training on complementary foods for children under two years (baduta). Likewise, nutritional counseling is rarely done in Integrated Services Post (Posyandu) because of the limited knowledge and resources of adequate cadres. The results of research findings in the Depok city area showed that the mothers have knowledge about nutrition and complementary children’s foods is still lacking. The community service program was carried out in the form of training involving 10 Posyandu represented by 28 cadres from Beji and East Beji Villages. The cadres’ engagement method is in a form of training. The purpose of training is to improve the nutrition, knowledge of complementary foods for children, and the skills of cadres in information & education, and counseling. The training took place on 29-30 August 2019. The facilitator from the Depok City Health Office, Center of Public Health Beji, and Universitas Indonesia. Cadres practiced information & education in Posyandu with the target of 129 infant mothers and counseling for twenty mothers under two years of children. The success of training is measured through pre-test and post-test for cadres and observations of skill cadres. An increase in cadre knowledge score after training by 11 points and category knowledge of cadres are sufficient and good. The results of cadre observations while information & education showed there were still shortcomings in terms of verbal reinforcement skills and fun activities such as singing. Cadre counseling activities still need to be improved in terms of conducting studies such as looking at maternal as child health books also recording counseling results. Training of cadres can improve the knowledge of complementary foods and skills of communication & education also counseling for the mother’s baduta
The Empowerment of Livestock Farmers in Subclinical Mastitis Test with GAMA Anti-Haptoglobin in “Sahabat Ternak” Etawah Crossbreed Goat Farm
Authors: Lestari Fajar Budi , Wasissa Madarina , Sahid Muhammad Novrizal Abdi , Salasia Siti Isrina Oktavia
Published: April 2022

Sahabat Ternak is one of the Etawah crossbreed (PE) goat farm groups in Sleman. This farm group focuses on goat milk production and processed goods. Problems that commonly arise in dairy goat farms are the cases of subclinical mastitis, which are quite high. This disease may cause a decrease in milk production and quality. The mastitis subclinical detection method which is often used by the farming community is the somatic cell count (SCC) and California mastitis test (CMT). However, both tests have low accuracy. Recently, a new method named GAMA Anti-Haptoglobin, which is more accurate and can be done easily has been established by livestock farmers. This community service aims to empower livestock farmers in applying GAMA Anti-Haptoglobin as a sensitive, rapid, and accurate subclinical mastitis detection kit in Sahabat Ternak goat farm. The method used in this activity consisted of discussion, socialization, and training for livestock farmers, as well as laboratory testing, evaluation of test findings, and treatment for PE goats. After the training, the livestock farmers were able to apply GAMA Anti-Haptoglobin mastitis detection method effectively. The implementation of this easy and accurate field mastitis detection method, as well as personnel with reliable skills, will support in the decrease of mastitis cases and increase milk production and quality, as well as community welfare.
Readability in Students’ General English Textbooks: An Empirical Study Based on Benchmark
Authors: Huang Chunbao
Published: March 2022

Reading is one of the most reliable sources of language input. As the main source of English input for non-English undergraduates, textbooks for General English play a critical role in developing their reading abilities. Based on the text readability benchmark of the reading tests in national College English Test (CET), this study aims to explore readability of the texts in an English coursebook series for general purpose used by non-English major undergraduates in a university from China, and tries to examine the impact of students’ reading coursebooks on their reading achievements in CET reading tests. Samples include 72 English texts from 4 target textbooks and 72 texts from the reading tests in CET between 2017 and 2021. Results show that the average text readability index from Book 1 to Book 4 is short of scientific variations despite the trend of a descending order. Besides, a noticeable gap in text readability has been discovered between the target books and CET. Given the guiding role CET has been playing in college English teaching and learning, it is proposed that reading materials selected for non-English undergraduates in and out of class should be more scientific by taking the readability benchmark in CET into consideration.
América Latina y el régimen de no proliferación nuclear
Authors: Ortega García Diana Patricia
Published: March 2022

Una de las mayores amenazas a las que se enfrenta la humanidad hoy en día es la posibilidad del uso de armas nucleares, tanto por parte de los Estados que las poseen legalmente como por los que tienen programas nucleares no autorizados internacionalmente. Para mitigar este desafío, el régimen de no proliferación nuclear regula el uso de este tipo de armamento. En contexto, este documento valora el conjunto de normas internacionales del régimen de no proliferación nuclear; por medio de una metodología cualitativa y a partir de una revisión de literatura, describe el proceso evolutivo del régimen, haciendo énfasis en el papel que han jugado los Estados latinoamericanos en la creación y fortalecimiento de esta legislación. Se identifica que el régimen cuenta con múltiples instrumentos para controlar el uso de este tipo de armamento; que América Latina ha hecho aportes positivos y que su territorio es considerado y respetado como un espacio no nuclear, convirtiéndose en un referente mundial en la lucha contra las armas de destrucción masiva.
Review Paper on Energy Management for Home Automation Using AI
Authors: S Sandeep , Patil Halashankar N , HS Arunkumar , S Yathish , K V Prof. Sandeep
Published: March 2022

Abstract: The smart energy management system was developed with the ability to record, store, and process power consumption data for all major home and industrial devices. Artificial intelligence technologies such as decision making and XG Boost have made advances in power electronics and energy engineering. These technologies provide powerful tools for designing, simulating, controlling, estimating, and fault diagnostic control of modern smart grids and renewable energy systems. AI technology has evolved rapidly over the past few decades, and its applications in modern industrial systems are growing rapidly. Power consumption data can be accessed from the web portal and handheld devices. Homeowners and industry companies can track power consumption by appliance, device, facility, or device. This allows you to better adjust your power consumption. Using the weather forecast, the system decides to switch between photovoltaics or grids using a machine learning concept-based deterministic algorithm. Keywords: Control of smart grid, Energy management system, Artificial Intelligence, Machine Learning, Decision making
Solar Roof Top System Structure Analysis and Its Cost Optimization
Authors: Gulalkari Aditya , Kalmegh Prajwal , Bokey Chinmay , Patil Anurodh , Mohod Tushar
Published: March 2022

Abstract: Nowadays the demand for clean, renewable energy sources is increasing. The use of renewable energy resource increasing rapidly. The structure plays an important role in stability of an entire solar mounting structure. The solar structure decide the life period of hole solar panel mounting system solar structure has to withstand different types of loading conditions and bear the weight of photo-voltaic panels. In this review paper, there is consideration about design and analysis and cost optimization of solar panel support structure by considering environmental effect like wind load, structural load and height of structure , material selection and also their properties . The analysis can be done by creating model in software and followed by analysis using different software to determine pressure distribution on the solar panel area and structure, then it can break and will be affect the power generation and also affect the life cycle of the hole solar panel mounting system. Keyword:-Solar panel, types of structures, wind load, structural Analysis, Cost Optimization.
Digital Strategic Governance in the Terrain of Ongoing New Normal: Prospects and Challenges for the Possible Next Normals
Authors: Arangil Arun
Published: April 2022

Abstract: For both businesses and consumers, the COVID-19 conundrum provides an early view into a future where all contacts will be conducted via digital technology, and the adoption curve will be accelerated almost immediately. At this moment in time, businesses have the potential to learn and advance at an unprecedented rate; therefore, playing it safe is often the wrong strategy. Many businesses are ill-equipped to keep up with the rapid rate of change in the marketplace. Digital technology adoption is strongly linked to value generation, according to a study by McKinsey & Co. Amid a crisis, it is crucial to push your digital agenda aggressively. During a crisis, mergers and acquisitions (M&A) can provide access to new goods, services, solutions, and new market and client segments while also helping organizations acquire people and increase capabilities. However, Richard Branson, CEO of McKinsey & Co., maintains that behaving boldly does not mean acting rashly. Exploration has become both required and expected in the wake of the COVID-19 issue. Making the most of this real-world experience will require mastering the art of productivity maintenance. Consider approaches to standardize your learning to promote the growth of digital solutions in the core business activities. It is challenging to keep up with the pace of change in the digital age, so look for ways to move projects along with more quickly. These hugely scaled digital projects are new digital projects for businesses in crisis mode. Many problems have arisen due to the rapid expansion of digital processes and interfaces to full size. It also provides the opportunity to learn where value is created in real-time. Businesses must find ways to streamline operations and avoid becoming overburdened with work. During this phase of forced virtualization, businesses have the opportunity to collect and evaluate client data in real-time for the first time. In studying the interaction effects of various factors, proliferation presents an ideal opportunity to proliferate. Until the crisis subsides, you can increase the possibility of keeping a more significant number of customers by combining unproductive operations and goods while aggressively fixing growing flaws with your services. Consider how you can best accommodate the learning styles of your talented staff
Automatic Liquid Filling Unit Using PLC
Authors: Suramwar Prof. P. V. , Meshram Ashish , Bhadke Pallavi , Pathode Pranali , Thakre Tejeshwini
Published: April 2022

Abstract: An Automation is the utilization of different control techniques for operating equipment’s such as operations in factories, aircraft and other applications with reduced human power. The filling process is a mission performed by a machine that fills liquid products such as water or cold drinks. Traditional bottling method include placing bottles on a conveyor belt and filling only one bottle at a time. In this paper, it has been designed and implement water filling machine system for different types of bottles by using PLC. Where the water filling machine system includes design and implement prototype of a flat belt conveyor with dimensions (300*40) mm and automatic process for water filling machine using the water pump and sensors which gives the appropriate information to control unit then design the controller using PLC. The PLC plays important role to implement automatic filling process by using PLC programing software and ladder diagram language. It was found that the water filling machine using PLC is less operational cost and less power consumption than the traditional control systems, in addition more flexible and time saving Keyword: PLC, conveyor, DC motor, inductive sensor, water pump, Relay, etc,,
TOTAL PRODUCTIVE MAINTENANCE IN LAB SET UP OF EDUCATIONAL SYSTEM – CASE STUDY
Authors: Sivasankaran Panneerselvam
Published: March 2022

Total productive maintenance (TPM) is used to evaluate the performance of equipment used within the manufacturing facility, lab set up etc. TPM Concept used to improve the efficiency of machinery by undergoing serious maintenance activities every day based on the usages. Productivity is defined as maintaining the workplace and surrounding facilities neat and clean. Equipment used for performing work is said to be monitored every time continuously. Due to the continuous observation about the performance of the equipment will help us to note down the conditions of equipment also suitable remedies to further increase its effective usages. In this paper, an attempt has been made to use TPM concepts (Total Productive Maintenance) in the lab to set up the environment within the technical education institution in south India. The case study is conducted to study the quality and effectiveness of lab instruments with the help of TPM concepts used in real-time applications.
Participatory science communication for transformation in Colombia
Authors: Ayure Mabel , Triana Ricardo
Published: March 2022

This essay approaches the question: ‘What does participatory science communication for transformation mean in Colombia?’ The answer comes from an examination of the public policy instruments that have promoted participatory scientific communication through the concept of social appropriation of science, technology, and innovation (STI). In the gaze of these public policy instruments, it is evident how the social appropriation of STI has been intended as a means of transformation.
Improving the Sphere of Customs Administration in Russia Based on the Chinese Experience
Authors: Vorona A. A. , Kalmykov S. P. , Lyashenko M. V.
Published: March 2022

The widespread use of new technologies based on digitalization has recently intensified, due to the processes associated with changes in business organization. Serious attention is paid to this direction of development by business representatives engaged in economic activities in international trade and governments of the leading economies of the world, including China and Russia. The introduction of digitalization processes in various sectors of the economy has become a conscious necessity. In order to theoretically substantiate and subsequently achieve the necessary level of development of information technologies and communications, analytical studies and testing of changes in this area are being conducted in many countries. The economy based on the introduction of digital technologies determines the vector of development of the economies of countries for the long term.

Aim. Analyze the digital transformation of the Chinese economy, identify positive experience in the application of digital solutions and their impact on the simplification of customs procedures and correlate the results with Russia.

Tasks. Consider technological trends in digital transformation; to study the results of the policy in carrying out the digitalization of the economy of China and Russia; to consider possible promising areas for the development of cooperation between China and Russia in the field of digital.

Methods. Statistical analysis of data and synthesis of the results obtained for comparison purposes.

Results. As a result of the study, the following results were obtained: a) a comparative analysis of the changes in the values of indicators on the Global Connectivity Index (GCI) of China and Russia in 2020 compared to 2015 was carried out, the reasons for the changes that occurred were substantiated; b) the dynamics of exports and imports of China, as well as data on trade turnover between China and Russia for the period from 1991 to October 2021; c) the experience of customs administration in China is considered and possible directions of its application in Russia are determined.

Conclusion. The positive experience of China’s customs administration in the light of the digitalization of economic processes can be used in Russia, which can certainly improve the current situation in the field of customs administration in our country.
The architectural evolution of the ancient Lebanese churches in Koura, Batroun and Byblos, from the 8th Century to the 13th Century.
Authors:   Department of Architecture, faculty of Engineering, Democritus University of Thrace – Greece 67100 Xanthi, Aziz Issa Ghassan
Published: April 2022

I think this work is intriguing for a wide circle of readers interested in the history of ancient Lebanese churches. Monumental historical temples are the symbol of cultural identity showing the spiritual value of their old period and reflecting the social, cultural and economic endurance of the past. They are the main part of the architectural heritage that signalizes the continuity of history and the important link between our time and history that helps to understand the development of the architectural features in time and space. Like in many countries, ancient churches need to be identified, classified and then assessed; for this reason, in this research, I will offer an overall picture of the original ecclesiastical parts, which is based on the latest architectural and documental data. The study of these structures is important because it helps to identify the structural forms, the disaster preparedness and the potential hazards. The original damaged and undamaged parts of these churches should be examined in order to achieve proper results, considering the first step to accomplish this, is to recognize them in their original status, so that the applied intervention could be implemented respecting these results. Documentation, protection and conservation of historic monuments are the most important procedures of the cultural heritage preservation, therefore large inventory of these temples should be well documented before starting to detailed analyses and restoration projects.
Entrevista con el Dr. Daniel Camacho Monge
Authors: Katsavavakis Giorgos
Published: March 2022

El sociólogo costarricense Daniel Camacho Monge es uno de los más importantes científicos sociales centroamericanos de los últimos 50 años.
The supercloseness property of the Stoke projection for the transient Navier-Stokes equations and global superconvergence analysis
Authors: Li Minghao , Xiao Liuchao , Li Zhenzhen , CHEN Hong-Ru
Published: March 2022

In this paper, we derive the supercloseness properties and global
superconvergence results for the implicit Euler scheme of the transient
Navier-Stokes equations. Using a prior estimate of finite element
solutions, the properties of the Stokes projection and Stokes operator,
the derivative transforming skill and the H-norm
estimate, we deduce the supercloseness properties of the Stokes
projection for the velocity in
L∞(H)-norm and pressure in
L∞(L)-norm. Then the supercloseness
properties of the interpolation operators are obtained for two pairs of
retangular element: the bilinear-constant element and the Bernadi-Raugel
element. Finally, by the interpolation postprocessing technique, we
obtain the global superconvergent results. The supercloseness analysis
is based on the Stokes projection, which makes the proof more concise.
Compared with previous superconvergence results, a lower regularity of
solution is needed, and no time step restrict is required.
Genomic divergence of Stellera chamaejasme through local selection on the Qinghai-Tibet Plateau and adjacent regions
Authors: Hu Hongyin , Yang Yongzhi , Li Ao , Zheng Zeyu , Zhang Jin , Liu Jianquan
Published: March 2022

Understanding how populations diverge and new species arise is a central
question in evolutionary biology. ‘Allopatric’ divergence through
geographic isolation is considered to be the commonest mechanism
generating species biodiversity in mountainous ecosystems. However, the
underlying genomic dynamics, especially genomic islands of elevated
divergence and genes that are highly diverged as a result of
lineage-specific selection, remain poorly understood. Stellera
chamaejasme is widely distributed on the Qinghai-Tibet Plateau and in
adjacent regions, making it a good model with which to explore genomic
divergence in mountainous ecosystems. We assembled a high-quality,
chromosome-level genome for this species and re-sequenced the genomes of
24 populations across its distributional range. Our population genomic
analyses recovered four distinct genetic lineages corresponding to
geographic distributions with contrasting environments. However, we
revealed that continuous gene flow occurred during the diversification
of these four lineages and inter-lineage hybrids, and plastome
introgressions were frequently found in regions of contact. The elevated
genomic divergences were highly heterogeneous across the genome. The
formation of such genomic islands showed neither correlation with rate
of gene flow nor relationship to time of divergence. The
lineage-specific positively selected genes potentially involved in local
adaptation were found both within and outside genomic islands. Our
results suggest that genomic divergence in S. chamaejasme is likely to
have been triggered and further maintained by local selection in
addition to geographic isolation.
Forced Expiratory Flows and Diffusion Capacity in Infants Born from Mothers with Pre-eclampsia
Authors: Ren Clement , Slaven James , Haas David , Haneline Laura , Tiller Christina , Hogg Graham , Bjerregaard Jeffrey , Tepper Robert
Published: March 2022

Rationale: Animal models suggest pre-eclampsia (Pre-E) affects alveolar
development, but data from humans are lacking. Objective: Assess the
impact of Pre-E on airway function, diffusion capacity, and respiratory
morbidity in preterm and term infants born from mothers with Pre-E.
Methods: Infants born from mothers with and without Pre-E were recruited
for this study; term and preterm infants were included in both cohorts.
Respiratory morbidity in the first 12 months of life was assessed
through monthly phone surveys. Raised volume rapid thoracoabdominal
compression and measurement of diffusion capacity of the lung to carbon
monoxide (DLCO)) were performed at 6 months corrected age. Results:
There were 146 infants in the Pre-E cohort and 143 in the control
cohort. The Pre-E cohort was further divided into non-severe (N=41) and
severe (N=105) groups. There was no significant difference in DCLO and
DLCO/aveolar volume amongst the three groups. Forced vital capacity was
similar amongst the three groups, but the non-severe Pre-E group had
significantly higher forced expiratory flows that the other two. After
adjusting for multiple covariates including prematurity, the severe
Pre-E group had a lower risk for wheezing in the first year of life
compared to the other two. Conclusions: Pre-E is not associated with
reduced DLCO, lower forced expiratory flows, or increased wheezing in
the first year of life. These results differ from animal models and
highlight the the complex relationships between Pre-E and lung function
and respiratory morbidity in human infants.
Deformation and Migration Measurements of U87 Glioma Cell Line using Dielectrophoresis in the Microfluidic Device
Authors: Elitas Meltem , Ozogul Beyzanur , Kaymaz Sumeyra Vural , Islam Monsur
Published: March 2022

Glioblastoma multiforme is the most aggressive malignant primary brain
tumor. We need to better understand its microenvironment to design
effective treatment strategies. Hence, characterization of glioma cells
while providing their genetic and phenotypic stability is crucial. Here,
we used dielectrophoresis (DEP) to underline the deformational
heterogeneity of U87 glioma cell line. We fabricated a gold
microelectrode array within a microfluidic channel and applied 3 V
and 30 kHz to 10 MHz frequencies to generate DEP
forces. We analyzed dielectrophoretic movement and deformation of 100
glioma cells. We observed that U87 glioma cells exhibited crossover
frequency around 100 kHz - 200 kHz. The mean dielectrophoretic
displacements of glioma cells were significantly different at varying
frequencies with the maximum and minimum travel distances of 13.22 µm
and 1.37 µm, respectively. The dielectrophoretic deformation indexes of
U87 glioma cells altered between 0.027 – 0.040. It was 0.036 in the
absence of dielectrophoretic forces. When we applied 3 V
and 30 kHz to 10 MHz frequencies, the mean
deformation indexes of the glioma cells did not significantly vary
between 30 kHz - 500 kHz. The mean value of the deformation index was
0.028 under the influences of strong positive DEP forces when 500 kHz to
10 MHz were applied.
Large-scale Genetic Surveys of a main extant population of wild giant panda (Ailuropoda melanoleuca), reveals a urgent need of human management
Authors: Li Wanyu , Zhou Chuang , Cheng Meiling , Tu Hongmei , Wang Guannan , Mao Yeming , Huang Yaohua , Chen Minghua , Price Megan , Meng Yang , Yue Bisong , Zhang Xiuyue
Published: March 2022

A comprehensive understanding the genetic health status is crucial for
the conservation of vulnerable species. Liangshan Mountains is one of
the main distribution areas of six living giant panda populations and is
outside the newly established Giant panda national Park. In this study,
971 giant panda fecal samples were collected in the heartland of
Liangshan Mountains (Mabian Dafengding Nature Reserve: MB; Meigu
Dafengding Nature Reserve: MG; and Heizhugou Nature Reserve: HZG).
Microsatellite makers and mitochondrial D-loop sequences were used to
establish individual genetic archives and estimate population size and
genetic diversity. We identified 92 individuals (MB: 27, MG: 22, HZG:
43) from the three reserves. Our results showed that: 1) Genetic
diversity of three giant panda populations was medium-low; 2) Quite a
few loci deviated significantly from the Hardy-Weinberg equilibrium and
almost all these deviated loci showed significant heterozygote
deficiencies and inbreeding; 3) Three giant panda populations have
substantial genetic differentiation with the most differentiation
between MB and the two other populations; 4) a large amount of giant
panda feces outside the three reserves were found, implying the
existence of protection gap. These results indicated that the giant
panda population in Liangshan Mountains is at an risk of genetic decline
or extinction given stochastic events and urgent need of human
management. This study revealed that high attention should be paid to
the protection of these giant panda populations outside the Giant panda
national Park, to ensure their survival in their distribution areas.
A Unique Presentation of Subcorneal Pustular Dermatosis
Authors: Ambur Austin , Nyckowski Timothy
Published: March 2022

IgA pemphigus is a rare autoimmune neutrophil predominant blistering
associated with IgA autoantibodies. The condition most commonly presents
as annular vesiculopustular plaques on the trunk, extremities, and
intertriginous regions. SPD may be associated with an underlying
gammopathy such as multiple myeloma.
Incidence and Risk Factors for Totally Implantable Venous Access Device Infections in Pediatric Patients with Cancer: A Study of 20,770 Device-Days
Authors: Lee Joon Kee , Choi Young Bae
Published: March 2022

Background: Totally implantable venous access devices (TIVADs) are
frequently used in pediatric patients with cancer owing to their
multiple benefits. Despite occasional infections with TIVADs, knowledge
of the incidence and risk factors is limited. Methods: This
retrospective study included pediatric patients with cancer who received
TIVAD at Chungbuk National University Hospital from 2001 to 2018. We
collected data on demographics, diagnosis, duration of TIVAD use,
pathogens, and other risk factors. Results: During the study period, 47
TIVADs with 20,770 device-days were applied in 42 patients. There were
14 TIVAD infections (14/47, 29.8%), with an infection rate of 0.25
infections per TIVAD per year (0.69 cases/1000 device-days). TIVAD
infections occurred at a median of 5.5 months (range, 8 days–30 months)
after insertion. The most common causative microorganisms were
methicillin-resistant coagulase-negative staphylococci (n = 8, 57.1%)
followed by Escherichia coli and Streptococcus mitis (n = 2, each). A
platelet count below 150,000/μL at the time of TIVAD insertion and
diagnosis of acute lymphoblastic leukemia (ALL) were the major risk
factors for TIVAD infection. Device removal was the mainstay of
treatment (11/14, 78.6%). Conclusion: TIVAD insertion was safe and
dependable in children with malignancies. Risk factors for TIVAD
infection included a platelet count below the normal range at the time
of device insertion and a diagnosis of ALL. Further studies are needed
to identify preventive factors against TIVAD infections in children with
cancer.