bluuebunny/crossref_metadata_2025 huggingface dataset:
Recognizing Limitations: Overcoming Challenges in Enhancing Health and Preventing Disease
Authors: Alzeer Jawad , Alzeer Jawad , Benmerabet Hamid
Published: June 2023

The advancement of human progress hinges on the ability to identify limitations and develop innovative solutions, particularly in the field of healthcare. While modern medicine has made significant strides in treating various illnesses, it often fails to address the root causes of diseases, impeding the recovery process for many patients. To overcome this challenge, healthcare professionals require a more comprehensive and integrative approach to healthcare that combines rational and logical thinking. Rationality offers a systematic and evidence-based method for understanding and treating diseases, providing healthcare professionals with a strong foundation for developing treatment plans. However, rational thinking has limitations in terms of our observational abilities, which can lead to misdiagnosis and ineffective treatments. On the other hand, logical thinking provides a more creative and flexible approach to problem-solving, which is particularly useful in addressing complex and multifaceted health issues. This approach enables healthcare professionals to think outside the box, consider alternative solutions, and tailor treatment plans to individual needs. By combining rational and logical viewpoints, healthcare providers can enhance their comprehension of a patient's condition, resulting in more favourable treatment results. Halalopathy, which employs a merged thought process, has been introduced to tackle the challenges and limitations of modern medicine. Halalopathy is a holistic healthcare approach that integrates rational and logical thinking, providing a more comprehensive understanding of illness prevention and disease at a physicopsychological level.
Calcium Phosphate Treatment Enhances Osteogenic Differentiation of Porcine Adipose-Derived Stem Cells on Fibrin Scaffolds
Authors: Wheeler Matthew B. , J. Maki Aaron , Chanaka Rabel R. A. , Wheeler Matthew B.
Published: June 2023

This study was designed to develop a fibrin scaffold for optimum in vitro osteogenic differentiation of porcine ASCs. Fibrin scaffolds physically and chemically modified to be stiffer or have higher concentrations of calcium and phosphate ions were hypothesized to enhance osteogenic differentiation compared to control fibrin scaffolds. Treatments during coagulation resulted in six scaffold types for comparison: whole blood controls, red blood cell lysis buffer, calcium chloride, calcium hydrogen phosphate, vacuum, and mechanical compression. Based on the results, fibrin supplemented with granules of calcium hydrogen phosphate (CaHPO4) was determined to be the most suitable formulation of those examined. Using calcium phosphate resulted in a fibrin scaffold that coagulated faster (p = 0.022), had a rougher surface, higher stiffness, and desirable properties for practical use during surgical operations and scaffolds used in bone tissue engineering. Further, osteogenic differentiation was enhanced on scaffolds treated with calcium phosphate. In addition, fibrin scaffolds treated with RBC lysis buffer were also stiffer than untreated controls. These results are partly explained by ASC attachment and fibrin polymerization during coagulation.
A INFLUÊNCIA DOS CRITÉRIOS DO DESENVOLVIMENTO SUSTENTÁVEL PARA A CONSTRUÇÃO DE POLÍTICAS ECONÔMICAS DE INCENTIVO AO DESENVOLVIMENTO AGRÍCOLA BRASILEIRO
Authors: Pscheidt Eduardo Luiz Soletti , Garcia Denise Schmitt Siqueira
Published: June 2023

O estudo desenvolvido aborda a relação entre os critérios do desenvolvimento sustentável e a construção das políticas econômicas de incentivo dentro do ordenamento jurídico brasileiro, dando enfoque ainda ao setor do Agronegócio como pauta, para tanto, o trabalho teve como objetivo geral analisar se o desenvolvimento sustentável é um critério observado para a construção de políticas econômicas de incentivo no ordenamento jurídico brasileiro, abordando ainda, como objeto de enfoque específico incentivos ao desenvolvimento agrícola brasileiro, sobretudo devido a sua influência do setor econômico e seu histórico impacto no meio ambiente. Estabeleceu-se ainda como objetivos específicos a conceituação de Direito Econômico, a identificação dos critérios do desenvolvimento sustentável na Constituição Federal de 1988, a conceituação de Desenvolvimento Econômico e por fim a exemplificação de programas econômicos de incentivo ao desenvolvimento agrícola sustentável. A Metodologia empregada, registra-se que, na Fase de Investigação foi utilizado o Método Indutivo, na Fase de Tratamento de Dados o Método Cartesiano, sendo que a pesquisa teve como Resultado a confirmação da hipótese, de que o Desenvolvimento Sustentável é um critério observado, na teoria, para a construção de Políticas Econômicas de Incentivo.
A EXTRAÇÃO DO OURO POR PARTE DAS EMPRESAS TRANSNACIONAIS EM FACE DO DIREITO AMBIENTAL CONSTITUCIONAL BRASILEIRO
Authors: Fiorillo Celso Pacheco
Published: June 2023

O objetivo deste artigo foi analisar de que maneira a extração do ouro realizada por empresas transnacionais poderá efetivamente se tornar uma alternativa sustentável no plano do desenvolvimento nacional do país em proveito das necessidades nacionais. Restou claramente demonstrado, que a extração do ouro por parte das empresas transnacionais, bem ambiental fundamental para o desenvolvimento de nossa economia, está submetida não só aos princípios fundamentais de nossa Carta Magna, como também aos princípios gerais da atividade econômica com destaque para os princípios da soberania e da defesa do meio ambiente (Arts.1º,IV e 170,I e VI da CF) encontrando no princípio da prevenção os mecanismos concretos destinados a dar efetividade à gestão do referido mineral em proveito de um desenvolvimento verdadeiramente sustentável.

Palavras-chave

Ouro.Empresas transnacionais.Direito ambiental constitucional.
Terminological basis and perspectives of the use of non-timber products of the forests of Ukraine
Authors: Píšová Soňa , Tokarieva Olha , Levchenko Viacheslav
Published: June 2023

In the forests of Ukraine, forestry should be carried out on the principles of continuous and rational use of forests through integrated usage of their resources. Thus, there is a need to distinguish and correctly understand the forestry terms. To harmonize terminology, relevant regulations, as well as Ukrainian and foreign literature, were examined. General scientific theoretical methods – analysis and synthesis – were applied to work with information sources. The paper substantiats the employment and understanding of terminology related to the usage of forest resources. The definition and interpretation of the terms “secondary forest use”, “non-tree forest resources”, “non-timber forest resources” in current legislative and regulatory acts, the explanatory dictionary of the Ukrainian language, the state standard of Ukraine, the Ukrainian encyclopedia of forestry, Ukrainian and foreign forestry literature were summarized. The authors proposes to divide forest resources into woody, non-tree, and non-timber ones, followed by coordination of such classification among forestry scientists and practitioners. The largest volumes of harvesting among secondary forest materials and secondary forest uses for 2010-2020 were established. The distribution of income received according to types of non-timber products of the forest and in the context of regional departments of forestry and hunting for 2021 was analysed. The paper presents the types of wild fruit, medicinal plants and mushrooms common in Ukraine. Promising species for plantation cultivation were proposed. Areas of obtaining added income from the sale of non-timber products of forests were generalized. The analysis and prospects of using non-timber forest products, which can serve as a theoretical and practical basis for sustainable management of multifunctional forestry in Ukraine, were presented. The obtained results can be used for harvesting non-timber products of forests, considering the regional characteristics of the country
UAV data collection parameters impact on accuracy of Scots pine stand mensuration
Authors: Zadorozhniuk Roman
Published: June 2023

A wide range of UAV systems used for forest research requires unified approaches to data collection. The research aims to determine the optimal parameters for UAV data collection to obtain accurate information about stands, considering the cost of resources for its collection. The process of collecting remote sensing data consisted of nine combinations divided into three levels of overlap and three levels of spatial resolution (survey altitude) and changing the degree of filtering of a dense point cloud during image processing. Individual tree detectingin the stand was performed using the R programming language and the ForestTools package. The results of the assessment of the dependence of the radius of tree crowns on their height were used to set the parameters of the variable filter function for finding local maxima for Scots pine stands. Errors in the identification of treetops were estimated using the F-score. The identified heights were compared with the field data of the ground survey. The proportion of classified digital elevation model DEM in the dense point cloud was reduced from the total area of the test site using images of 4.1 cm/pix spatial resolution (150 m survey altitude). The study presents the results of assessing the impact of spatial resolution of optical images collected from UAVs and their overlap on the results of measurements of stands parameters. It is determined that a photogrammetric survey with input images with a longitudinal overlap of less than 90% is not appropriate for the study of forest areas due to the impossibility of aligning all images. The results of the assessment of tree accounting in the stand showed that it is most appropriate to use images with a spatial resolution of up to 3.3 cm/pix (120 m survey altitude), otherwise, the proportion of missed treetops increases. Reducing the spatial resolution of remote sensing data leads to an increase in errors in determining the height of individual trees, and the average heights of the experimental plots had the same trend. Given the combination of the assessed factors, it is not recommended to use images with a spatial resolution of more than 3.3 cm/pix for forestry research due to increased errors in the individual tree detection and tree height determination. The results obtained can be used to select data collection parameters for research on Scots pine stands to assess their growing stock and phytomass
Perlindungan Hukum Terhadap Anak Sebagai Korban Tindak Pidana Pemerkosaan
Authors: Er Tanjung  , Sulastri Lusia , Rabiah Al Adawiah
Published: June 2023

Kejahatan pemerkosaan yang mencemaskan adalah kejahatan yang korbannya anak-anak yang masih di bawah umur. Para pelaku harus dipidana seberat-beratnya karena telah merusak masa depan anak bahkan dapat menimbulkan akibat buruk secara psikologis terhadap perkembangan anak. Anak yang mengalami tindak pidana persetubuhan dapat mengalami trauma yang mendalam dan gangguan psikologis maupun fisiknya karena pada hakikatnya anak harus dilindungi. Tujuan penelitian yang hendak dicapai adalah untuk mengetahui upaya perlindungan hukum terhadap anak yang menjadi korban tindak pidana pemerkosaan dan mengetahui pertanggungjawaban pidana terhadap pelaku pemerkosaan anak di bawah umur. Penelitian ini menggunakan penelitian normatif karena penelitian ini menguraikan permasalahan-permasalahan yang ada untuk selanjutnya dibahas dengan kajian teori-teori hukum yang berlaku. Hasil penelitian ini menunjukkan bahwa upaya perlindungan hukum terhadap anak yang menjadi korban tindak pidana pemerkosaan masih kurang. Perlindungan yang dilakukan baru sebatas pemberian hukuman yang setimpal terhadap pelaku, bahkan menurut penulis hukuman yang diberikan belum cukup setimpal terhadap pelaku, sementara anak sebagai korban mengalami kerugian baik secara materiil maupun immaterial belum mendapatkan perhatian.
Akibat Hukum Terhadap Tidak Dilakukan Penghapusan (Roya) Jaminan Fidusia Setelah Kredit Lunas
Authors: Ni Putu Sawitri Nandari  , Dewa Krisna Prasada  , Kadek Julia Mahadewi  , Tania Novelin  , Dewa Ayu Putri Sukadana
Published: June 2023

Kewajiban hukum adalah sebuah tindakan yang harus dikerjakan oleh seseorang. Setiap tindakan yang dikerjakan tersebut merupakan bentuk dari rasa tanggung jawab dari permasalahan yang sedang terjadi, baik itu secara hukum atau moral. Oleh sebab itu, kewajiban akan selalu melekat pada kehidupan manusia dalam melakukan sosial bermasyarakat. Aaturan mengenai kewajiban bagi penerima fidusia untuk melakukan penghapusan (roya) fidusia apabila hutang yang telah diperjanjikan sudah lunas, namun perlu diketahui juga mengenai akibat hukum apabila kewajiban penghapusan (roya) jaminan fidusia tersebut tidak dilaksanakan maka dapat mengakibatkan kerugian bagi pemberi fidusia. Dalam hal ini muncul permasalahan “Bagaimana akibat hukum  terhadap tidak dilakukannya penghapusan (roya) jaminan fidusia setelah kredit lunas. Metode penelitian yang dipergunakan adalah jenis penelitian yuridis-normatif yaitu yang menempatkan hukum sebagai sistem norma dalam mengkaji dan menganalisis akibat hukum tidak dilakukannya penghapusan (roya) jaminan fidusia. Jenis pendekatan yang dipergunakan adalah pendekatan peraturan perundang-undangan dan pendekatan analisis konsep hukum. Hasil dari kajian pembahasan terkait akibat hukum tidak dilakukannya penghapusan (roya) jaminan fidusia tidak ditemukan aturan yang tegas terkait hal tersebut, baik pada UU No. 42 Tahun 1999, PP No. 21 Tahun 2015, Permenkumham No. 9  Tahun 2013, dan Permenkumham No. 10 Tahun 2013, karena hal yang diatur masih sebatas kewajiban untuk melakukan penghapusan (roya) jaminan fidusia, sehingga tidak ada ancaman hukuman atau sanksi hukum bagi pelanggarnya secara tegas. Sedangkan upaya hukum yang dapat ditempuh pemberi fidusia yang mengalami kerugian atas tindakan penerima fidusia yang lalai dalam melakukan penghapusan (roya) jaminan fidusia tersebut adalah dengan cara mengajukan gugatan Perbuatan Melawan Hukum (PMH).
Pengaturan Pemberlakuan Pembatasan Kegiatan Masyarakat di Provinsi Bali Dalam Upaya Penanggulangan Penyebaran Covid 19 Menuju Bali Era Baru
Authors: Julia  Mahadewi Kadek
Published: June 2023

Tujuan  studi ini mengkaji  keberlakuan  hukum pengaturan  Pembatasan  Kegiatan Masyrakat di  Provinsi  Bali sudah  sesuai  dengan  tata  hukum  Nasional .  Studi  ini menggunakan  pendekatan  hukum  empiris,  dengan sifat  penelitian  yang  deskriptif.Pengaturan  Pembatasan  Kegiatan  Masyarakat  berdasarkan  Peraturan  Gubernur  Provinsi  Bali  No 40  Tentang  Penerapan  Protokol  Kesehatan   ditegaskan  lagi  dikeluarkanya  pada  Surat Edaran  Gubernur  Bali  Nomor 7  Tahun  2021  Tentang  Pengaturan  Pembatasan  Kegiatan  Masyarakat menunjukan  bahwa  belum  efektifnya  penerpan hukum  di dalam  masyarakat  ini  bisa dilihat  masih  tingginya  jumlah   angka  terpapar  Covid 19  sehingga  Pemerintah  terus  memuat  aturan  baru  dan   memperpanjang  Pengaturan  Pemabatasan  Kegiatan  Masyarat  untuk  menekan laju  perkembangan  Covid  19.
Pertanggungjawaban Wali Dalam Menjalankan Kekuasaan Terhadap Harta Anak Di Bawah Umur Setelah Berakhirnya Perwalian
Authors: Kartika Gusmawati  , Masri Esther , Otih Handayani
Published: June 2023

Wali merupakan orang yang diberikan kewenangan untuk melakukan suatu perbuatan hukum demi melindungi kepentingan anak yang tidak memiliki kedua orang tua atau kedua orang tuanya tidak cakap melakukan perbuatan hukum. Pertanggungjawaban wali terhadap pribadi dan harta anak yang berada di bawah perwaliannya hingga anak tersebut dewasa dan cakap dalam melakukan perbuatan hukum. Metode penelitian yang penulis gunakan adalah yuridis normatif yakni penelitian studi kepustakaan dengan menelaah peraturan perundang-undangan yang berkaitan dengan permasalahan atau isu hukum yang sedang dihadapi. Hasil penelitian penulis bahwa harta anak yang di bawah perwalian berupa benda tetap seperti tanah dan bangunan serta kepemilikan hak atas tanahnya masih atas nama wali maka saat berakhirnya perwalian atau anak dinyatakan dewasa wali berkewajiban dan bertanggung jawab menyerahkan seluruh harta anak tersebut dengan melakukan peralihan hak berupa hibah yang harus dibuatkan akta hibah di hadapan Pejabat Pembuat Akta Tanah (PPAT) melalui prosedur hukum yang benar. Kemudian, penerima hibah harus mengurus proses peralihan hak atas tanah ke kantor Badan Pertanahan Nasional agar status hibah tersebut menjadi hak miliknya.
REDUPLIKASI DALAM BAHASA ARAB DAN BAHASA INDONESIA: STUDI KONTRASTIF
Authors: Radhi Billah Muhamad Athfan , Muta’ali Abdul , Asisi Datang Frans
Published: June 2023

Artikel ini bertujuan untuk mendeskripsikan dan membandingkan reduplikasi yang terjadi dalam bahasa Arab dan Indonesia. Artikel ini mencoba menunjukkan hal apa yang menjadi persamaan dari reduplikasi dalam kedua bahasa meskipun reduplikasi jarang terjadi dalam bahasa Arab. Reduplikasi utuh terjadi dalam kedua bahasa, tetapi reduplikasi sebagian dan imitatif hanya terdapat dalam bahasa Indonesia. Dengan analisis deskriptif yang telah dilakukan, ditemukan 11 fungsi reduplikasi dalam bahasa Arab, yaitu urutan berseri, formasi kata, distribusi, penekanan, intensitas, permohonan, tahapan, sumpah, peringatan, subordinasi, dan bagian dari bagian. Sementara itu, dalam bahasa Indonesia ditemukan sedikitnya 16 fungsi, yaitu pluralitas, membentuk adverbia, klausa konsesif, klausa korelatif, bentuk kasual, kontinuitas, intensitas, belum terjadi, urutan berseri, merendah diri, penekanan, varietas, diminutif, kuantifer, timbal balik, indefinit, dan lain-lain. Dengan analisis kontrastif, ditemukan bahwa urutan berseri, penekanan, intensitas, dan adverbia (distribusi dan tahapan) adalah fungsi-fungsi reduplikasi kata yang dapat ditemukan dalam kedua bahasa.
Profile of Sensitization to Allergenic Components in Patients with Respiratory Allergic Pathology
Authors: Lykovа M. A. , Zaikov S. V.
Published: June 2023

Abstract. Respiratory allergic diseases, which include allergic rhinitis and bronchial asthma, are a serious medical and social problem worldwide due to their high prevalence and negative impact on the quality of life of the relevant category of patients. The development of respiratory allergy pathology is usually caused by inhaled allergens, which are divided into seasonal: tree, grass or weed pollen, as well as year-round — house dust mites, mold, pet epithelium. But at the same time, respiratory manifestations of allergic pathology are often combined with its non-respiratory manifestations, which affects the profile of sensitization of patients to various allergens and requires a personalized approach to specific allergy diagnostics and immunotherapy. The aim of this study was to study the profile of sensitization to the components of various allergens in patients with respiratory allergic pathology. Materials and methods. The results of a multiplex study (determination of specific IgE to 112 allergenic proteins using the ImmunoCap ISAC test system) in 291 patients who applied to the Clinic of Allergology and Immunology “Forpost” with signs of respiratory allergic pathology were analyzed. Results. Among the seasonal allergens, the most frequent causes of sensitization were spring tree proteins (PR10) — Bet v1, timothy and meadow grasses Phl p1, and ragweed Amb a1. Among year-round allergens, sensitization to the major allergenic component of cats — uteroglobin Fel d1, major components of house dust mites and mold fungi Alternaria alternata was most often detected. Among the allergenic proteins of dogs, sensitization to urinary kallikrein Can f5 was most common. The vast majority of examined patients also had sensitization to food allergens of three main groups of proteins — thermolabile proteins (PR10), lipid transport proteins (LTP), or tropomyosin. Conclusions. In the structure of sensitization among adult patients, the main components of pollen allergens of spring trees (Bet v1), meadow grasses (Phl p1) and ragweed (Amb a1) play an important role. Year-round allergens include cat allergens (Fel d1), house dust mites (Der р1, Der f1, Der p2, Der f2) and Alternaria alternata mold (Alt a1). In patients with hypersensitivity to dog and house dust mite allergens, it is necessary to determine the presence of antibodies to such important components as Can f5 and Der p23. Sensitization to minor components of allergens was detected much less often, however, the appropriate determination of antibodies to them is also important, as it affects the choice of patient treatment tactics. Sensitization to food products in persons with respiratory allergic diseases is due to cross-properties of inhaled and food allergens due to PR10, LTP and tropomyosin molecules.
Програмні засоби для людей з порушеннями зору: аналіз досліджень у наукометричній базі даних Scopus
Authors: Пірогов Владислав Миколайович , Мінтій Ірина Сергіївна
Published: June 2023

У статті здійснено аналіз досліджень у наукометричній базі даних Scopus за ключовими словами "color blindness", "software", "information technology". Більша частина робіт з даної проблематики належить до медичної галузі і лише 13 джерел стосуються програмного забезпечення чи інформаційних технологій. Це актуалізує і доводить необхідність досліджень щодо розробки програмного забезпечення для людей з порушеннями кольоросприйняття.
Distance learning expert and leader
Authors: Kukharenko Vladimir N. , Shunevych Bohdan I. , Kravtsov Hennadiy M.
Published: June 2023

The paper deals with the theoretical foundations of training experts and leaders of distance learning in order to improve their training program. An expert is a specialist who has an experience in developing distance courses, conducting distance learning classes and has and uses the skills of a content curator. Leaders create the conditions for innovative changes that allow people and organizations to share their vision and move in its direction, contribute to the management and implementation of ideas. The paper describes the basic skills to be developed by an expert and a leader, provides typical mistakes of distance course developers. Training of experts and leaders was based on the distance course ”Distance Course Examination” for experienced developers of distance learning courses and administrators of distance learning systems from different organizations. During the training, students analyzed the purpose of learning according to the Bloom’s taxonomy and its accessibility, the complexity of the text and its design, tasks and learning activities, test quality and evaluation system as well as other elements responsible for the quality of learning. During the pilot training, the results were obtained in the form of reports of students about the examination of the distance course as well as analysis of this work was done. 47 teachers of educational institutions of Ukraine were trained and only 12 teachers successfully completed their training. Based on the results of training and taking into account the experience of emergency training during the pandemic and military actions in Ukraine, the course program has been refined. It is planned to use a team of experts, ”playing” coaches and new methods for conducting distance learning. Particular attention is paid to training experts, leaders and measuring their competencies.
Analysis of Hematological Parameters According to TSH Levels in Thyroid Patients
Authors: YAYLACI Selcuk , DEMİRCİ Taner , ÖZDİN Mehmet
Published: June 2023

Objective: In this study, it was aimed to investigate hematological parameters according to thyroid stimulating hormone (TSH) levels in thyroid patients.

Materials and Methods: Thyroid function tests and hemogram data of 5130 thyroid patients admitted to our hospital between January 2019 and August 2021 were analyzed retrospectively.

Results: There was no significant difference between hemoglobin, MCH, leukocyte, basophil and thrombocyte levels according to TSH levels. When compared in terms of MCV, a significant difference was found between group 1 (TSH
The Influence of Accountability, Participation, and Transparency of Boss Funds on the Financial Performance of Public Elementary Schools in Palembang City
Authors: Putri Dela Septiani , Saftiana Yulia , Siddik Saadah , Kushendar Kushendar
Published: June 2023

This study examines and analyzes the effect of accountability, participation, and transparency of boss funds on the financial performance of public elementary schools in Palembang City. The data used are primary data with a population of all public elementary school financial treasurers in the city of Palembang, as many as 251 people; the sampling method uses probability sampling with the sampling technique, namely simple random sampling, so the study uses 72 people as the research sample. The analysis technique used is quantitative with an analytical tool, namely multiple linear regression. The results showed that accountability and transparency of boss funds had a positive and significant effect on the financial performance of elementary schools. In contrast, participation had a negative and insignificant effect on the financial performance of elementary schools.
The Self-Esteem of Generation Z As Leaders: A Study on The Student Council Board for the 2022/2023 School Year at SMA 1 Rejang Lebong
Authors: Ristianti Dina Hajja
Published: June 2023

Self-esteem or good self-esteem is important for a leader.  This study aims to determine the self-esteem of the student council board of SMA N 1 Rejang Lebong for the 2022/2023 period who is Generation Z. This study was conducted by providing a self-esteem instrument consisting of 40 questions used to reveal the level of valuable or worthless self-assessment seen in general, personal and social. After being given, the instrument is processed manually which begins with checking, sorting answer sheets, correcting according to norms, and printing results individually or in groups. The results showed that the self-esteem of the student council board of SMA N 1 Rejang Lebong for the 2022/2023 period was included in the medium category as much as 64.8%. This shows that the self-esteem of student council administrators must still be strengthened through leadership development, such as internships, training, or mentorship. They also need to strengthen their self-belief, learn from experiences, and seek support from people who trust and support them.
The Relationship Between Learning Discipline and Learning Achievement Students in Civics Subjects
Authors: Loriana Pabalik  , Nani Mediatati  , Yosaphat Haris Nusarastriya
Published: June 2023

This study aims to determine the relationship (correlation) between student learning discipline and student learning achievement in Civics subject in class X SMK Negeri 2 Salatiga. The samples in this study were students of class X TKJ B and X DPIB B who were taken by nonrandom sampling, a total of 70 students. The data collection techniques used questionnaires and documentation. The data analysis technique uses the Product Moment correlation statistical test from Person. Based on the results of the statistical correlation test, it shows that there is a significant positive correlation between learning discipline and Civics learning achievement of class X students of SMK Negeri 2 Salatiga. The results of the correlation analysis (test) between the learning discipline variable and student learning achievement show a positive correlation of r = 0. 302 with a significant level of 0.011 <0.05. With this positive correlation result is shows that learning achievement is not entirely influenced by learning discipline factors, but also influenced by factors outside the learning discipline. Although the contribution (contribution) of learning discipline to learning achievement is small, the habit of learning discipline must still be instilled in students.
PENGARUH VARIASI BEBAN TERHADAP EFISIENSI KINERJA TURBIN GAS UNIT MEB 2 DI PLTGU PANARAN
Authors: Lathif Muhammad , Toar Handri
Published: June 2023

Unit PLTGU Panaran beroperasi secara terus menerus selama 24 jam, akibatnya sering mengalami perubahan beban dan mempengaruhi efisiensi dari pembangkit. Efisiensi yang berbeda disetiap beban kerja akan berdampak pada perbandingan biaya produksi dan jumlah produksi yang dihasilkan. Penelitian ini dilakukan dengan tujuan mengamati pengaruh variasi beban terhadap efisiensi turbin gas unit MEB 2 di PLTGU Panaran. Teknik pengumpulan data yang digunakan yaitu dengan mengumpulkan data primer bulan September 2022 dari Central Control Room. Metode penelitian yang digunakan adalah analisis regresi linear sederhana. Berdasarkan persamaan regresi  Ŷ = 0,269052261 + 0,003088346X menunjukkan bahwa nilai konstanta sebesar 0,269052261. Dari penelitian ini didapatkan bahwa pada beban ±23 MW, ±25 MW, dan ±27 MW nilai rata-rata efisiensi termal masing-masing sebesar 34,15 %; 34,87 %; dan 35,30 %. Pengaruh dari variasi beban terhadap efisiensi kinerja turbin gas yaitu efisiensi termal naik dengan bertambahnya beban.
PENGARUH KINERJA CHILLER TERHADAP TEMPERATUR UDARA MASUK UNTUK MENINGKATAKAN OUTPUT GENERATOR DI PT A UNIT 1
Authors: Nash Muhammad Khoirun , Toar Handri
Published: June 2023

Turbin gas harus dijaga performanya untuk menghasilkan output generator yang optimal. Salah satu faktor yang mempengaruhi performa turbin gas adalah temperatur udara lingkungan turbin gas. Pengaruh temperatur udara lingkungan turbin gas berdampak pada output daya dan efisiensi sistem. Idealnya turbin gas beroperasi dengan kapasitas 100 % pada suhu standar ISO yaitu 15 °C dan suhu ISO lebih rendah dengan suhu ambien di Indonesia. Oleh karena itu dibutuhkan suatu sistem yang dapat menurunkan suhu udara masuk atau suhu ambien pada turbin gas. Dengan menggunakan Chiller maka Inlet Ambient akan turun sehingga mempengaruhi performa dari sistem. Pada penelitian ini kinerja Chiller dilambangkan dengan COP (coefficient of performance). Pada penelitian ini penulis menghitung kinerja Chiller untuk memperoleh nilai COP kemudian dihubungkan terhadap Inlet Ambient Temperature untuk memperoleh nilai Output Generator. Setelah itu penulis membandingkan Output Generator yang sudah didapat dengan Output Generator ketika tidak menggunakan Chiller. Dengan demikian didapatkan hasil peningkatan output rata-rata generator sebesar 2.79 MW dengan penurunan suhu inlet rata-rata sebesar 1.87 °C ketika menggunakan Chiller.
PERUBAHAN NILAI EFEKTIVITAS KONDENSER SEBELUM DAN SESUDAH PEMELIHARAAN UNIT 2 DI PLTGU PANARAN
Authors: Simangunsong Ronaldo , Gozali Muhammad Syafei
Published: June 2023

Kondenser Pembangkit Listrik Tenaga Gas Uap (PLTGU) Batam merupakan peralatan utama yang berfungsi untuk mengubah uap sisa dari turbin menjadi air yang dapat digunakan kembali, dalam prosesnya menggunakan air pendingin dari air laut yang digunakan sebagai media pendingin, pada proses pengambilan air laut masih banyak kotoran yang masuk sehingga dapat membuat kebersihan di dalam tube-tube kondenser, selain itu air laut juga dapat menyebabkan korosi pada waterbox. Hal ini bisa membuat proses perpindahan panas tidak maksimal sehingga membuat efektivitas kondenser akan mengalami penurunan, kegiatan pemeliharaan di PLTGU ini dilakukan pada bulan September 2022. penelitian ini menggunakan metode efektivitas dan perpindahan panas maka akan terlihat faktor yang membuat penurunan pada kondenser. Hasil dari analisa untuk nilai laju perpindahan panas terbesar sebelum pemeliharaan 57.981,117 kW sedangkan nilai laju perpindahan panas (Qcondensing) terbesar sesudah pemeliharaan 58.456,218 kW. Sedangkan untuk efektivitas terbesar kondenser sebelum pemeliharaan 54,8 % setelah pemeliharaan nilai efektivitas kondenser terbesar mengalami kenaikan nilai sebesar 56,9 %.
ANALISIS KONDUKTIVITAS LISTRIK PADA KITOSAN DARI LIMBAH RAJUNGAN DI PACIRAN SEBAGAI BAHAN ELEKTROLIT PADA BIO-BATERAI
Authors: Saputra Trisna jaya , Fadli Ulfa Mahfudli , Basith Abdul
Published: June 2023

Baterai merupakan alat elektrokimia yang dibuat untuk mensuplai energi listrik ke sistem starter mesin, lampu-lampu, sistem pengapian dan komponen kelistrikan lainnya. Baterai merupakan sebuah media yang dapat mengubah energi kimia yang terkandung dalam bahan aktif secara langsung menjadi energi listrik. Elektroda dan elektrolit merupakan komponen utama pada baterai. Prinsip kerja pada baterai menggunakan prinsip elektrokimia dengan memanfaatkan proses reduksi-oksidasi. Elektroda positif (+) disebut anoda sedangkan elektroda negative (-) disebut katoda. Bio-Baterai adalah perangkat penyimpanan energi listrik yang elektrolitnya menggunakan bahan organik, Penggunaan polimer sintesis sebagai bahan elektrolit ternyata masih memiliki beberapa kekurangan. Selain harganya yang mahal, dampak lingkungan akibat menumpuknya sampah kimia juga menjadi salah satu permasalahan berbagai jenis material terus dikembangkan dalam pembuatan elektrolit pada bio-baterai. Kitosan mempunyai sifat pengikat ion, tidak beracun, biodegradable (dapat terurai) dan memiliki gugus pasangan elektron bebas yang bisa dijadikan elektrolit dengan nilai konduktivitas yang baik. Kitosan disintesis melalui tahap demineralisasi, deproteinasi dan deasetilasi kemudian dikarakterisasi menggunakan FTIR untuk memastikan bahwa gugus fungsi kitosan telah terbentuk. Pada pengujian konduktivitas, aquades yang ditambahkan kitosan terjadi peningkatan nilai konduktivitas.
IMPLEMENTASI PROGRAM SANITASI TOTAL BERBASIS MASYARAKAT (STBM) PILAR PERTAMA DI DESA BOLA
Authors: Nirma Oliva Nurhayati , Lado Anita
Published: June 2023

Di Desa Bola, Kecamatan Bola, Kabupaten Sikka melaksanakan Program pemerintah terkait STBM (sanitasi total berbasis masyarakat) dengan indikator pilar sebagai berikut: stop Buang Air Besar Sembarangan (BABS), Cuci Tangan Pakai Sabun, Pengolahan Air Bersih, Pengolahan Sampah, Pengolahan Limbah Cair. Penelitian ini bertujuan untuk mengetahui dampak program STBM khususnya untuk pilar pertama stop BABS di Desa Bola. Peneltian ini menggunakan metode kualitatif dengan metode pemicuan. pembahasan penelitian ini menunjukan bahwa implementasi program STBM pilar pertama telah dilaksanakan dengan baik dan lancar sesuai dengan tahapan-tahapan yang dirancangkan. Semua fasilitator baik dari dinas kesehatan maupun pemerintah desa telah memonitoring serta mengevaluasi  dengan verifikasi terhadap pelaksanaan program pengadaan jamban sehat bagi masyarakat.
ПЕДАГОГІЧНА ПАРАДИГМА М. ДАРМАНСЬКОГО ПРО ХРИСТИЯНСЬКІ ЦІННОСТІ ОСОБИСТОСТІ ПЕДАГОГА
Authors: ПІСОЦЬКА Леоніда
Published: June 2023

У статті розкрито педагогічну парадигму, обґрунтовану М. М. Дарманським, у контексті формування християнських цінностей у педагога і їх вплив на його особистість через трансформування педагогічного та управлінського досвіду. Педагогічну парадигму трактовано як сукупність теоретичних і методологічних підходів, що визначають систему освіти, втілювану в науці і практиці.

На підставі вивчення наукових праць і практичної діяльності М. Дарманського доходимо висновку, що педагог може стати високодуховною особистістю, якщо розуміє свою професійну місію і володіє духовним потенціалом. У статті акцентовано увагу на важливості християнських цінностей у педагогічній діяльності, які сприяють формуванню особистості з альтруїстичними якостями, рефлексією, толерантністю тощо. Аналіз наукових та практичних досліджень М. Дарманського підтверджує, що виховання та навчання є основними факторами розвитку особистості, а педагог повинен мати провідну роль у формуванні християнських цінностей через власну поведінку. Акцентовано увагу на необхідності конкретизації християнських цінностей в освітньому процесі та ролі педагога у цьому. Зазначено, що підготовка педагогів має базуватись на інтеграції фундаментальної, спеціальної та психолого-педагогічної підготовки, а принципами такої підготовки є єдність філософії та освіти, полікультурність.
In situ-formed hyaluronan gel/BMP-2/hydroxyapatite composite promotes bone union in refractory fracture model mice
Authors: Saito Hiroki , Shoji Shintaro , Kuroda Akiyoshi , Inoue Gen , Tazawa Ryo , Sekiguchi Hiroyuki , Fukushima Kensuke , Miyagi Masayuki , Takaso Masashi , Uchida Kentaro
Published: June 2023

BACKGROUND: A combination of synthetic porous materials and BMP-2 has been used to promote fracture healing. For bone healing to be successful, it is important to use growth factor delivery systems that enable continuous release of BMP-2 at the fracture site. We previously reported that in situ-formed gels (IFGs) consisting of hyaluronan (HyA)-tyramine (TA), horseradish peroxidase and hydrogen peroxide enhance the bone formation ability of hydroxyapatite (Hap)/BMP-2 composites in a posterior lumbar fusion model. OBJECTIVE: We examined the effectiveness of IFGs-HyA/Hap/BMP-2 composites for facilitating osteogenesis in refractory fracture model mice. METHODS: After establishing the refractory fracture model, animals were either treated at the site of fracture with Hap harboring BMP-2 (Hap/BMP-2) or IFGs-HyA with Hap harboring BMP-2 (IFGs-HyA/Hap/BMP-2) (n = 10 each). Animals that underwent the fracture surgery but did not receive any treatment were considered the control group (n = 10). We determined the extent of bone formation at the fracture site according to findings on micro-computed tomography and histological studies four weeks following treatment. RESULTS: Animals treated with IFGs-HyA/Hap/BMP-2 demonstrated significantly greater bone volume, bone mineral content and bone union than those treated with vehicle or IFG-HyA/Hap alone. CONCLUSIONS: IFGs-HyA/Hap/BMP-2 could be an effective treatment option for refractory fractures.
Disparities in public understanding, attitudes, and intentions during the Covid-19 pandemic: The role of health literacy
Authors: McCaffery Kirsten J. , Ayre Julie , Dodd Rachael , Pickles Kristen , Copp Tessa , Muscat Danielle M. , Nickel Brooke , Cvejic Erin , Zhang Michael , Mac Olivia , Isautier Jennifer , Cornell Samuel , Wolf Michael S. , Bonner Carissa
Published: June 2023

The Covid-19 pandemic has highlighted the need to address health literacy as a critical priority for public health. Health literacy is crucial during a pandemic for understanding and following health advice and for navigating vast amounts of information and misinformation. However, public health communication globally has inadequately met the needs of low literacy and culturally and linguistically diverse groups. This review examines the role of health literacy and how it is related to Covid-19 related outcomes, as well as how public health communication has routinely failed to follow basic health literacy principles. Lessons from the pandemic about health communication and recommendations for how health literacy needs can be addressed in the future are discussed. Improving public health communication requires an immediate short-term response and longer-term investment to build the health literacy responsiveness of public health units, health organisations, and government departments to meet health literacy population needs.
Longitudinal Effects of Herpesviruses on Multiple Cognitive Outcomes in Healthy Elderly Adults
Authors: Weidung Bodil , Josefsson Maria , Lyttkens Peter , Olsson Jan , Elgh Fredrik , Lind Lars , Kilander Lena , Lövheim Hugo
Published: June 2023

Background: Herpesviruses have been proposed to be involved in Alzheimer’s disease development as potentially modifiable pathology triggers. Objective: To investigate associations of serum antibodies for herpes simplex virus (HSV)-1 and cytomegalovirus (CMV) and anti-herpesvirus treatment with cognitive outcomes in relation to interactions with APOE ɛ4. Methods: The study included 849 participants in the population-based Prospective Investigation of the Vasculature in Uppsala Seniors study. Cognitive performance at the ages of 75 and 80 years was assessed using the Mini-Mental State Examination (MMSE), trail-making test (TMT) A and B, and 7-minute screening test (7MS). Results: Anti– HSV-1 IgG positivity was associated cross-sectionally with worse performance on the MMSE, TMT-A, TMT-B, 7MS, enhanced free recall, and verbal fluency tests (p = 0.016, p = 0.016, p < 0.001, p = 0.001, p = 0.033, and p < 0.001, respectively), but not orientation or clock drawing. Cognitive scores did not decline over time and longitudinal changes did not differ according to HSV-1 positivity. Anti– CMV IgG positivity was not associated cross-sectionally with cognition, but TMT-B scores declined more in anti– CMV IgG carriers. Anti– HSV-1 IgG interacted with APOE ɛ4 in association with worse TMT-A and better enhanced cued recall. Anti– HSV IgM interacted with APOE ɛ4 and anti-herpesvirus treatment in association with worse TMT-A and clock drawing, respectively. Conclusion: These findings indicate that HSV-1 is linked to poorer cognition in cognitively healthy elderly adults, including impairments in executive function, memory, and expressive language. Cognitive performance did not decline over time, nor was longitudinal decline associated with HSV-1.
Association Between Sensory Impairment and Dementia: The Roles of Social Network and Leisure Activity
Authors: Dintica Christina S. , Calderón-Larrañaga Amaia , Vetrano Davide Liborio , Xu Weili
Published: June 2023

Background: Evidence suggests that sensory impairment is linked to dementia; however, the role of social network and leisure activity in this relationship is unclear. Objective: Examine the association of hearing and visual impairment with dementia, and whether a rich social network and leisure activity moderates this association. Methods: Dementia-free older adults from the Swedish National Study on Aging and Care in Kungsholmen (n = 2,579) were followed up for up for a median of 10 years (interquartile range = 6). Visual impairment was assessed with a reading acuity test, and hearing impairment was ascertained via self-report and medical records. Dementia was diagnosed following international criteria. Data on social network and leisure activity was collected via self-report. Hazard ratios (HRs) of dementia risk were derived from Cox regression models. Results: Dual impairment, but not single impairment in hearing and vision was associated with a higher risk of dementia (HR: 1.62, 95% CI: 1.16 to 2.27). Compared to participants with no sensory impairment and a moderate-to-rich social network, those with dual impairment and low social network or leisure activity had higher dementia risk (HR: 2.08, 95% CI: 1.43 to 3.22; HR: 2.08, 95% CI: 1.43 to 3.22, respectively), whereas participants with dual impairment with a moderate-to-rich social network or leisure activity did not have significantly higher dementia risk (HR; 1.42, 95% CI: 0.87 to 2.33; HR; 1.42, 95% CI: 0.87 to 2.33, respectively). Conclusion: A richer social network and participation in stimulating activities may mitigate the higher dementia risk in older adults with dual impairment in vision and hearing.
Sundowning in Patients with Dementia: Identification, Prevalence, and Clinical Correlates
Authors: Toccaceli Blasi Marco , Valletta Martina , Trebbastoni Alessandro , D’Antonio Fabrizia , Talarico Giuseppina , Campanelli Alessandra , Sepe Monti Micaela , Salati Emanuela , Gasparini Marina , Buscarnera Simona , Salzillo Martina , Canevelli Marco , Bruno Giuseppe
Published: June 2023

Background: The term sundowning is used to describe the emergence or worsening of neuropsychiatric symptoms in late afternoon or early evening in people with dementia. Objective: Our aim was to evaluate sundowning’s prevalence and clinical manifestations among patients attending a tertiary memory clinic and to investigate its clinical and neuropsychological correlates. Methods: Patients with dementia attending our memory clinic were enrolled in the study. Sundowning was identified through a specifically designed questionnaire. Sociodemographic and clinical features of sundowners and non-sundowners were compared, and a logistic regression was performed to identify the variables associated with the phenomenon. A subgroup of patients underwent a complete neuropsychological assessment. Results: Among 184 recruited patients, 39 (21.2%) exhibited sundowning, mostly expressed as agitation (56.4%), irritability (53.8%), and anxiety (46.2%). Sundowners were significantly older, had a later dementia onset, exhibited more severe cognitive and functional impairment, more frequent nocturnal awakenings, and hearing loss relative to non-sundowners. They were also more likely to use anticholinergic medications and antipsychotics, and less likely to use memantine. In a multi-adjusted model, the factors significantly associated with sundowning were the Clinical Dementia Rating score (OR 3.88; 95% CI 1.39–10.90) and the use of memantine (OR 0.20; 95% CI 0.05–0.74). Participants with and without sundowning obtained similar results in single domain neuropsychological tests. Conclusion: Sundowning is commonly experienced by patients with dementia and appears as a multiply determined condition. Its presence should always be evaluated in clinical practice and a multidimensional approach should be adopted to identify its predictors.
Alzheimer’s Disease and Neurosyphilis: Meaningful Commonalities and Differences of Clinical Phenotype and Pathophysiological Biomarkers
Authors: Milano Chiara ,   Neurodegeneration Precision Medicine Initiative (NPMI), Hoxhaj Domeniko , Del Chicca Marta , Pascazio Alessia , Paoli Davide , Tommasini Luca , Vergallo Andrea , Pizzanelli Chiara , Tognoni Gloria , Nuti Angelo , Ceravolo Roberto , Siciliano Gabriele , Hampel Harald , Baldacci Filippo
Published: June 2023

Background: Neurosyphilis-associated cognitive and behavioral impairment— historically coined as “general paralysis of the insane”— share clinical and neuroradiological features with the neurodegenerative disease spectrum, in particular Alzheimer’s disease (AD). Anatomopathological similarities have been extensively documented, i.e., neuronal loss, fibrillary alterations, and local amyloid-β deposition. Consequently, accurate classification and timely differential diagnosis may be challenging. Objective: To describe clinical, bio-humoral, brain MRI, FDG-PET, and amyloid-PET features in cases of neurosyphilis with an AD-like phenotypical presentation, as well as clinical outcome in terms of response to antibiotic therapy. Methods: We selected the studies comparing patients with AD and with neurosyphilis associated cognitive impairment, to investigate candidate biomarkers classifying the two neurological diseases. Results: The neuropsychological phenotype of general paralysis, characterized by episodic memory impairment and executive disfunction, substantially mimics clinical AD features. Neuroimaging often shows diffuse or medial temporal cortical atrophy, thus contributing to a high rate of misdiagnosis. Cerebrospinal fluid (CSF)-based analysis may provide supportive diagnostic value, since increased proteins or cells are often found in neurosyphilis, while published data on pathophysiological AD candidate biomarkers are controversial. Finally, psychometric testing using cross-domain cognitive tests, may highlight a wider range of compromised functions in neurosyphilis, involving language, attention, executive function, and spatial ability, which are atypical for AD. Conclusion: Neurosyphilis should be considered a potential etiological differential diagnosis of cognitive impairment whenever imaging, neuropsychological or CSF features are atypical for AD, in order to promptly start antibiotic therapy and delay or halt cognitive decline and disease progression.