bluuebunny/crossref_metadata_2025 huggingface dataset:
New Strain of Bacillus amyloliquefaciens G1 as a Potential Downy Mildew Biocontrol Agent for Grape
Authors: Qiao Wenyan , Kang Xingjiao , Ma Xiwei , Ran Longxian , Zhen Zhixian
Published: July 2024

To obtain effective biocontrol strains for downy mildew of grape, 38 endophytic bacteria were isolated from fruits, seeds, and old stems of six grape varieties. Using spot inoculation mixtures of sporangial suspensions of Plasmopara viticola and biocontrol bacterial suspension, this screen yielded three strains (G1, G5, and G9) with good antagonistic effects against P. viticola. The growth inhibition rate was 100%, which was comparable to the effect of the positive control Bacillus subtilis strain CN181. The enzyme activity and the metabolites of strain G1 were examined on casein hydrolysate medium, sodium carboxymethyl cellulose agar plates, and chrome azurol sulfonate (CAS) agar plates. The antifungal protein component was identified by liquid chromatography–mass spectrometry (LC–MS). The results showed that strain G1 was more effective against Plasmopara viticola after two field trials, and the inhibition rates of strain G1 on the seventh day of the two field trials were 47.5% and 36.9%, respectively. Strain G1 was identified as Bacillus amyloliquefaciens based on morphological examination and 16S rDNA sequence analysis. It produced proteases, cellulases, and siderophores. Crude protein of the strain mainly included the putative segregation protein SpoVG, which inhibited P. viticola.
Early Cholecystectomy after Endoscopic Retrograde Cholangiopancreatography Is Feasible and Safe
Authors: Büyükkasap Çağrı , Algan Deniz , Balakji Nigar , Metindoğan Onur , Karataş Ali , Yavuz Aydın , Göbüt Hüseyin , Dikmen Kürşat , Kekilli Murat , Bostancı Hasan
Published: July 2024

Laparoscopic cholecystectomy (LC) following endoscopic retrograde cholangiopancreatography (ERCP) is the preferred treatment for cholelithiasis with common bile duct stones. However, the optimal timing of LC after ERCP remains controversial. This study aimed to identify the ideal time interval between ERCP and LC. Data from patients who underwent LC after ERCP between November 2016 and August 2022 were retrieved from the electronic medical information system. The patients were categorized into early cholecystectomy (within 72 h of ERCP) and delayed cholecystectomy (after 72 h). The impact of the time interval between ERCP and LC on perioperative outcomes was analyzed. A total of 197 patients were included in the study, with 45 undergoing early cholecystectomy and 152 undergoing delayed cholecystectomy. No significant differences in the preoperative characteristics or operative morbidity were observed between the groups (p = 0.286). However, a significant correlation was found between the time interval from ERCP to LC and the total length of stay (r = −350, p < 0.001). The findings suggest that early cholecystectomy after ERCP is feasible and safe, and performing LC within the first 72 h does not adversely affect postoperative outcomes.
Research on Food Preservation Based on Antibacterial Technology: Progress and Future Prospects
Authors: Chu Zejing , Wang Hongsu , Dong Biao
Published: July 2024

The nutrients present in food are not only prone to a series of physicochemical reactions but also provide conditions for the growth and reproduction of foodborne microorganisms. In recent years, many innovative methods from different fields have been introduced into food preservation, which extends the shelf life while maximizing the preservation of the original ingredients and properties of food. In this field, there is a lack of a systematic summary of new technologies emerging. In view of this, we overview the innovative methods applied to the field of food preservation in recent 3 years, focusing on a variety of technological approaches such as antimicrobial photodynamic therapy based on nanotechnology, electromagnetic radiation sterilization based on radiation technology, and antimicrobial peptides based on biomolecules. We also discuss the preservation mechanism and the application of the different methods to specific categories of products. We evaluated their advantages and limitations in the food industry, describing their development prospects. In addition, as microorganisms are the main causes of food spoilage, our review also has reference significance for clinical antibacterial treatment.
Analysis of Electric Breakup Characteristics of Emulsion Droplets Based on Dissipative Particle Dynamics Method
Authors: Geng Yiyang , Lv Changhai , Yuan Xin , Xu Weiwei
Published: July 2024

Crude oil desalination and dehydration are necessary for storage, transportation, and processing procedures. However, the behaviour of fine emulsion droplets under an electric field has always been questioned. This paper modified the dissipative particle dynamics method (DPD) to study the deformation process of fine emulsion droplets under a high-strength electric field. Compared with the literature data, the reliability of the DPD method is confirmed. The influence of the crude oil properties and the electric field characteristics on the behaviour of the emulsion droplet was analysed, and the effect factors included electric field intensity, electric field frequency, emulsion droplet size, centre distance ratio, conservative force intensity, dissipative strength, and crude oil density. The relationship between critical electric field intensity and emulsion droplet deformation was formulated based on the simulational dates.
Greening the Economy from the Ground Up: How the Minimum Wage Affects Firms’ Pollution Emissions in China
Authors: Ren Haili , Zhu Ming , Lyu Bofei
Published: July 2024

The implications of minimum wage standards have been widely debated, but their effects on firms’ pollution emissions and the underlying mechanisms remain underexplored. This paper finds that the introduction of minimum wage standards significantly reduces emissions of pollutants such as carbon dioxide and sulfur dioxide. Firms respond to rising minimum wages by optimizing their product mix, enhancing technological innovation, and improving managerial efficiency, which collectively curb pollution outputs. Our analysis using a random forest model shows that these effects are most pronounced in regions with higher economic development, stringent environmental regulations, and elevated minimum wage standards. Our findings augment the body of research on minimum wage standards and introduce novel insights for emission reduction strategies for firms.
Integration of Adasyn Method with Decision Tree Algorithm in Handling Imbalance Class for Loan Status Prediction
Authors: Ami Rahmawati  , Yulianti Ita , Mardiana Tati , Pribadi Denny
Published: July 2024

Determining the provision of credit is generally carried out based on measuring credibility using credit analysis principles (5C principles). However, this method requires quite a long processing time and is very susceptible to subjective judgments which might influence the final results. This research uses data mining techniques by developing modeling on loan status prediction datasets. The stages in this research include data preprocessing, modeling, and evaluation using accuracy metrics and ROC graphs. In this analysis, it is known that there is a class imbalance in the processed dataset, so an oversampling technique must be carried out. This research uses the ADASYN (Adaptive Synthetic) Oversampling technique to ensure the class distribution is more balanced. Then, the ADASYN technique is integrated with the Decision Tree Algorithm to build a prediction model. The research results show that the two methods can increase prediction accuracy by 12.22%, from 73,91% to 85.22%. This improvement was obtained by comparing the accuracy results before and after using the ADASYN Oversampling technique. This finding is important because it proves that implementing such integration modeling can significantly improve the performance of classification models and provide strong potential for practical application in helping more effective loan status predictions.
Ethical Sales Behavior Influencing Trust, Loyalty, Green Experience, and Satisfaction in UAE Public Entrepreneur Firms
Authors: Ahli Marwa , Hilmi Mohd Faiz , Abudaqa Anas
Published: July 2024

Customer satisfaction (CST) is a critical focus for both public and private organizations due to its significant impact on business success. In this context, ethical sales behavior, perceived trust, customer loyalty, and green experience are identified as key factors influencing CST. This study aims to examine the relationships among these variables within public sector organizations in the UAE. Primary data were collected from 224 respondents using a structured questionnaire. The data analysis was conducted utilizing descriptive statistics, multivariate assumptions, and a two-step approach that included both measurement and structural models. Structural equation modeling techniques were employed to test the relationships between the variables, grounded in the Resource-Based View (RBV) and expectation confirmation theory. The findings reveal that perceived trust, customer loyalty, and green experience significantly and positively impact customer satisfaction among public firms in the UAE. However, ethical sales behavior did not demonstrate a significant direct effect on customer satisfaction. These results provide valuable insights for policymakers and administrative representatives in the UAE public sector. To enhance customer satisfaction, it is recommended that public sector organizations prioritize building trust and loyalty while integrating green practices into their operations. Although ethical sales behavior does not directly affect customer satisfaction, it remains crucial for influencing trust and loyalty. The study underscores the importance of these factors in driving customer satisfaction and offers practical recommendations for public sector organizations aiming to improve their service quality and customer relations.
Long-Term Management of Chronic Rhinosinusitis with Nasal Polyps with Dupilumab
Authors: Бойко Н.В. , Стагниева И.В. , Лодочкина О.Е. , Курбатова Н.В.
Published: July 2024

Введение. Лечение хронического риносинусита с полипами (ХРСсП) – одна из самых актуальных проблем ринологии, особенно при тяжелом неконтролируемом течении заболевания. Биологическая терапия дает новые возможности для улучшения контроля заболевания и избавления пациентов от необходимости применения системных кортикостероидов и повторных хирургических вмешательств. Цель. Изучить критерии эффективности дупилумаба у пациентов с хроническим риносинуситом с полипами и коморбидной астмой. Материалы и методы. 10 пациентов с ХРСсП и коморбидной астмой получали лечение дупилумабом в течение 24 недель. Комплексное исследование, включающее заполнение пациентами опросников SNOT-22 (Sino-nasal Outcome Test-22) и анкеты по контролю симптомов астмы АСТ (Asthma Control Test), эндоскопическое исследование полости носа, спиральную компьютерную томографию (СКТ) околоносовых пазух, определение уровня системной эозинофилии и содержания общего иммуноглобулина Е (IgE) в сыворотке крови, было проведено перед началом и после 24 недель лечения дупилумабом. Результаты. У всех пациентов, проходивших курс лечения дупилумабом, по истечении 24 недель отмечено уменьшение выраженности клинических признаков как ХРСсП, так и коморбидной астмы. Это подтверждается достоверным уменьшением показателей SNOT-22, шкалы Lund – Mackay, содержания общего IgE в сыворотке крови и увеличением показателя АСТ. Заключение. Маркерами эффективности лечения пациентов с хроническим риносинуситом с полипами и коморбидной астмой могут быть изменения на СКТ околоносовых пазух, характеризуемые по шкале Lund – Mackay, содержание общего IgE в сыворотке крови и динамика SNOT-22 и АСТ.

Introduction. Managing chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most urgent challenges of rhinology, especially in severe uncontrolled course of the disease. Biological therapies offer new opportunities for improving the disease management and relieving patients from the need for systemic corticosteroids and repeated sinus surgeries. Purpose. To study dupilumab efficacy criteria in patients with CRSwNP and comorbid asthma. Materials and methods. 10 patients with CRSwNP and comorbid asthma were treated with dupilumab for 24 weeks. SNOT-22 (Sino-nasal Outcome Test-22), Asthma Control Test (ACT), endoscopic total polyp score (TPS), the Lund – Mackay score were applied, systemic eosinophilia and total serum immunoglobulin E (IgE) level were measured before and after 24 weeks of treatment with dupilumab. Results. All patients treated with dupilumab demonstrated a decrease in the severity of clinical signs of both CRSwNP and comorbid asthma by the end of 24 weeks of therapy. This is confirmed by a significant decrease in SNOT-22, Lund – Mackay score, and total IgE in blood serum, and by an increase in ACT. Conclusion. The Lund – Mackay score, total IgE in the blood serum, and SNOT-22 and ACT trends may be considered as possible dupilumab efficiency markers inpatients with CRSwNP and comorbid asthma.
Pyogenic Granuloma of the External Auditory Canal: A Case Report
Authors: Кузьмин Д.М. , Фионова Т.В. , Кустов М.О.
Published: July 2024

Пиогенная гранулема (капиллярно-дольчатая гемангиома) – это доброкачественная сосудистая опухоль кожи и слизистых оболочек, чаще всего возникающая в области головы и шеи, преимущественно в ротовой полости. В статье представлено описание клинического случая пиогенной гранулемы наружного слухового прохода как редкого явления, подробно изложены жалобы пациента, данные анамнеза, методы диагностики. Хирургическое лечение новообразования выполнялось двумя различными методами в связи с агрессивным ростом и рецидивированием опухоли. После повторного вмешательства с использованием горячего метода достигнуто стойкое рубцевание раны в месте роста пиогенной гранулемы без признаков нейтрофильной экссудации.

Pyogenic granuloma (lobular capillary hemangioma) is a benign vascular tumor of the skin and mucous membranes, most often occurring in the head and neck, mainly in the oral cavity. The article describes a clinical case of pyogenic granuloma of the external auditory canal as a rare phenomenon; the patient’s complaints, anamnesis data and diagnostic methods are described in detail. Surgical treatment of the neoplasm was performed by two different methods due to aggressive growth and recurrence of the tumor. After repeated intervention using the hot method, a persistent scarring of the wound at the site of pyogenic granuloma growth was achieved without signs of neutrophilic exudation.
DIAGNOSTIC POTENTIAL OF C-REACTIVE PROTEIN IN SEPSIS IN ONCOHEMATOLOGICAL PATIENTS
Authors: Наумова Л. А. ,   Surgut State University, Surgut, Russia, Яллыев М. Б. , Басараб В. А. , Петрова Н. В. , Зинина Е. Е. , Колодяжная М. А. , Попова Н. Б. ,   Surgut State University, Surgut, Russia,   Surgut State University, Surgut, Russia,   Surgut State University, Surgut, Russia,   Surgut District Clinical Hospital, Surgut, Russia,   Surgut District Clinical Hospital, Surgut, Russia,   Surgut District Clinical Hospital, Surgut, Russia
Published: July 2024

The study aims to analyze the dynamics, diagnostic, and prognostic significance of C-reactive protein (CRP) in sepsis in oncohematological patients. The CRP levels were compared in 30 patients with lymphoproliferative diseases using two designs. The first design included patients who received cytostatic therapy (groups 1 and 3 with and without complications, respectively), as well as patients who received autologous hematopoietic stem cell transplantation after cytostatic therapy (groups 2 and 4 with and without complications, respectively). The second design consisted of two groups of patients: the first with sepsis (n = 15) and the second without any complications (n = 15). In statistical analysis, the Mann–Whitney U test or Student’s t-test (at p < 0.05) were used to compare quantitative indicators according to the distribution type, and the ROC curve (AUC) was used to assess the diagnostic significance of CRP in predicting a specific outcome. Statistically significant differences were found in the level of CRP in both groups with sepsis compared to the corresponding groups without sepsis (p1–3 < 0.001, p2–4 < 0.001), the level of CRP depending on the outcome (recovery/death) in both study designs (p < 0.05), and the dynamics of CRP when comparing groups with sepsis. When assessing the diagnostic significance of CRP, AUC = 0.862 ± 0.029 with 95 % CI: 0.806–0.918, sensitivity (Se) was 85.7 % and specificity (Sp) was 69.7 %. When predicting 10-day mortality, AUC = 0.756 ± 0.069 with 95 % CI: 0.621–0.892, Se was 57.9 % and Sp was 89.2 %, the model was statistically significant (p < 0.001) in both cases. As an available marker, CRP has good diagnostic value in the comprehensive sepsis diagnosis, in particular in hematological oncology patients.
HUMAN RESPIRATORY SYSTEM’S ADAPTATION TO LOW TEMPERATURE FACTORS IN THE NORTHERN REGION
Authors: Литовченко О. Г. ,   Surgut State University, Surgut, Russia, Литвинова Н. С. ,   Tyumen State Medical University, Tyumen, Russia
Published: July 2024

The article reviews scientific publications on the human respiratory system’s adaptation to low temperature factors in the northern regions of Russia. It is shown that cold, as a pulmonotropic factor, has a significant impact on the human respiratory system, leading to modifications in the respiratory system intended to reduce the trauma caused by prolonged exposure to low temperatures. The present findings show that there is a decrease in maximum voluntary ventilation and forced vital capacity of the lungs with a concomitant increase in residual volume and functional residual capacity of the lungs throughout the process of human respiratory system adapting to the North environment.
Peningkatan Sikap Kerjasama dan Hasil Belajar Menggunakan Model Problem Based Learning Berbantuan Media Audio Visual
Authors: - Adilya Wahyu Ningtyas , Ratnasari Diah Utami
Published: July 2024

Penelitian ini berdasarkan rendahnya hasil belajar pembelajaran IPAS kelas IV SD. Hal tersebut disebabkan karena siswa belum berperan aktif dalam kegiatan pembelajaran sehingga hasil belajar siswa rendah. Perbaikan kualitas pembelajaran dilakukan melalui model PBL berbantu media audio visual yang dapat menunjang kegiatan pembelajaran dan hasil belajar sisiwa. Tujuan dari penelitian ini yaitu untuk mengetahui peningkatan sikap kerjasama dan hasil belajar peserta didik menggunakan model PBL berbantuan media audio visual pada muatan IPAS. Penelitian ini merupakan penelitian tindakan kelas dengan subjek penelitian adala sisiwa kelas IV SD Muhammadiyah 16 Surakarta yang berjumlah 24 siswa. Teknik pengumpulan data dalam penelitian ini menggunakan observasi dan nilai Pengetahuan dengan instrument penelitian sesuai aspek yang dinilai. Teknik analisis data yang digunakan adalah Teknik deskriptif kuantitatif.. Hasil penelitian menunjukkan bahwa penggunaan model Problem Based Learning (PBL) berbantuan media audio visual dapat meningkatkan hasil belajar siswa dan sikap kerjasama pada pembelajaran IPAS, dikarenakan dengan model dan berbantuan media siswa menjadi lebih tertarik untuk mengikuti pembelajaran. Peningkatan hasil belajar ditunjukkan dengan meningkatnya nilai rata-rata siswa  pada siklus I sebesar 73,04, pada siklus II sebesar 80,29.
Agroecologia e território camponês: desafios da formação por alternância na EFAMI
Authors: Baraúna Ian Mendes , Silva Lucimara Santos da , Silva Rosemary Lopes Soares da
Published: July 2024

O presente trabalho analisa a partir dos dados do inventário da realidade como a agroecologia  é materializada no trabalho pedagógico da Escola Família Agrícola dos Municípios Integrados da Região de Irará, identifica os desafios para a formação em agroecologia na EFAMI sob perspectiva das múltiplas dimensões do território camponês, apresenta um inventário da realidade que contempla aspectos diversos do território camponês  e subsidia o trabalho educativo na EFAMI. A metodologia utilizada foi fundamentada no pensamento de Marx, a partir do método do materialismo histórico dialético. O caminho metodológico percorreu a revisão de literatura a partir de estudiosos interessados em explicar o movimento da realidade, que tem a dialética como explicação e a expressão do movimento da realidade, isto é, a dialética como lógica, no campo da filosofia e como teoria do conhecimento, como método de pesquisa. Nesta perspectiva foram analisados os dados do inventário da realidade do território camponês da EFAMI. Inventariar a realidade é um trabalho constante, pois a realidade da escola é dinâmica e multifatorial, interage com os sujeitos em diferentes espaços e tempos, das suas histórias de vida. Estas histórias encontram-se integradas aos condicionantes sociais, históricos e políticos da formação do território brasileiro, com suas mudanças e permanências, o que nos leva a construção de novos trabalhos, novas percepções a partir de observações que modelam a teoria-prática das atividades da EFAMI.
A Literature Review on Cultural Routes: Bibliometric Analysis with Vosviewer
Authors: Zengin Gengörü Esra , Öcalır Ebru Vesile
Published: July 2024

Understanding the evolution of interconnected cultures and individuals, resembling a complex network, cultural routes serve as bridges between the past and the future, offering the key to cultural richness, diversity, and change. Defined as paths gathered around a specific theme, expressing a common value, cultural routes aim to preserve cultural heritage and support sustainable development and local economic growth. The concept of cultural routes, increasingly present in the literature, is addressed by various researchers through publications in different categories. This study aims to conduct a bibliometric analysis by examining publications related to cultural routes to reveal the dimensions of interaction between researchers and the impacts of their work. Utilizing the Web of Science database with data obtained in September 2023 using the keywords “cultural routes” and “cultural route”, a bibliometric analysis was conducted using the VosViewer program, examining a total of 236 publications. The study is considered significant in determining the direction of the trend in the literature regarding cultural routes.
La razón de ser de las jornadas de Derecho Penal económico en la Universidad de Ibagué
Authors: Lozano Delgado Augusto
Published: July 2024

En la Universidad de Ibagué se llevó a cabo la xv Jornada de Derecho Penal Económico el día 7 de septiembre de 2023. En dicho evento tuvo como enfoque el derecho penal económico, sus aspectos criminológicos, la política criminal y la victimología. Este tema es relevante en el ámbito del derecho penal actual. El presente texto tiene la pretensión de exponer varios comentarios sobre las distintas jornadas de derecho penal económico que se han celebrado en dicho claustro universitario.
Reseña de la XV Jornada de Derecho Penal Económico
Authors: Reyes Aldana Natalia Isabela
Published: July 2024

El 7 de septiembre de 2023 se llevó a cabo la xv Jornada de Derecho Penal Económico, organizada por la Facultad de Derecho y Ciencias Políticas, en el auditorio central de la Universidad de Ibagué. Las conferencias, presentadas por profesores de las universidades de Ibagué, Tolima y Javeriana, giraron en torno a los aspectos criminológicos, la política criminal y la victimología. Además, durante el evento se rindió homenaje al Dr. Jorge Augusto Lozano Delgado por sus aportes al derecho penal económico.
„Nie przenoście nam stolicy do Kijowa”
Authors: Łuczaj Kamil
Published: July 2024

The article aims to supplement knowledge on the social consequences of the full-scale aggression against Ukraine launched by Russia in February 2022 with an analysis of the discourse of resentment towards Ukraine and the Ukrainians. Based on a study of online videos posted on YouTube and CDA.pl, the author provides answers concerning who the makers of such messages are, what content makes up the discourse of the so-called “Ukrainization”, and how this content is constructed. The study discussed here constitutes a kind of reflection on the general mechanisms behind the creation and dissemination of xenophobic discourses. Symbolic power exercised through traditional media contributed to the emergence of a media-based narrative of Polish-Ukrainian friendship, of mutual kindness, and of the assistance provided by one side and resulting in the gratitude of the other. However, new information and communication technologies have brought about the dissipation of this power, one of the consequences of which may include the making and watching of niche views incompatible with the grand narrative reiterated in interpersonal interactions and in the prevailing media content.
THE ROLE OF FINANCIAL CONTROLLING IN THE FUNCTIONING OF FINANCIAL MARKET ENTITIES
Authors: Kladnytska Tatiana , Artimonova Iryna , Kemenyash Iryna , Svynous Nadiya
Published: July 2024

Introduction. At the stage of development of the Ukrainian economy, the efficiency of the financial market entities increasingly depends on the applied technologies and management methods. To ensure the manageability of such systems, new management methods are needed that correspond to the complexity of the external and internal environment of financial market entities. In these conditions, it becomes necessary to use the achievements of controlling, which coordinates the work of functional services and provides information and analytical support to management during management decision-making. Methods. For the implementation of the set tasks in the process of scientific research, a logical-dialectical approach and methods of scientific knowledge, such as observation, comparison, abstraction, methods of decomposition, analysis and synthesis, were used. Results. If the enterprise decides to implement a new information system, then it has the following alternative automation of financial controlling: either by implementing an ERP system (Enterprise Resource Planning System), a BPM system (Business Performance Management) or by using a cheaper analytical system . The result of the implementation of financial controlling is a system that contributes to increasing the efficiency of the financial and economic activity of the enterprise and allows predicting the results of this activity. An important stage is the evaluation of the effectiveness of the application of this system. Discussions. The post-war reconstruction of the country's economy will lead to the formation of new requirements for the system of financial controlling of financial market entities, which will lead to the process of adapting foreign methods to the domestic realities of commodity-money relations. Keywords: financial controlling, economic entities, financial market, financial and economic activity, technology.
ASSESSMENT OF THE PRICE SITUATION ON THE MILK MARKET IN THE CONDITIONS OF THE INTRODUCTION OF MARTIAL LAW IN THE COUNTRY
Authors: Paska Igor , Satyr Larisa , Kepko Valentyna
Published: July 2024

Introduction. The market of milk and dairy products is a component of the food market, the level of development of which depends not only on the supply of the population with these most important food products, but also on the food security of the state. The dairy sub-complex is usually one of the most significant and at the same time problematic industries for the national economy. Lagging behind the volume of production of milk and dairy products from the growth of population needs, shortage of quality raw materials, low efficiency of production - these and a number of other negative factors are characteristic of most farms of all forms of management - producers of dairy cattle products. Methods. In accordance with the tasks, the following research methods were used: to study the research object and its individual components, methods of statistical observation, analysis and synthesis, variations were used; to compare indicators by year - methods of comparison, absolute and relative values, series of dynamics. Such methods as abstraction, analogies, calculation-constructive, monographic, etc. have also been widely used in the work. The results. The price situation on the milk market in the conditions of Russia's military aggression against Ukraine is analyzed. Factors affecting the level of purchase prices for milk received both from agricultural enterprises and households for processing have been identified. A comparative analysis of purchase prices for milk of domestic producers and EU countries was carried out. Discussions. We believe that the state should regulate purchase prices for milk, but not by direct intervention, but by means of commodity interventions. This scheme works in all developed countries of the world. when the price of milk falls, the state begins to actively buy milk powder or oil, supporting milk producers. Thus, the price of raw materials increases. When the price rises too much, the government starts selling milk powder and oil stocks, and prices fall. In our opinion, one of the important factors supporting purchase prices is the introduction of a state order for the supply of dairy products, which is financed from the funds of the state and local budgets. Keywords: price, milk, market, state regulation, processing enterprise, agricultural producers.
Gambaran Kejadian Miopia pada Mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi
Authors: Sambulele Ananda P. , Najoan Imelda H. M. , Supit Wenny P.
Published: July 2024

Abstract: Myopia is a condition in which incoming light is focused in front of the retina, causing distant objects to appear blurred. The prevalence of myopia is increasing rapidly and becoming a challenge to quality of life. Myopia is on the rise not only in children, but also in young adults. If left untreated, it can lead to serious complications and even blindness. This study aimed to determine the incidence of myopia among students of the Faculty of Medicine, Universitas Sam Ratulangi. This was a quantitative and descriptive study using a cross-sectional design. Subjects were students of the Faculty of Medicine, Universitas Sam Ratulangi who suffered from myopia taken by purposive sampling technique. The results showed that 31 students suffered from myopia, of which 26 students (83.9%) had low myopia. Myopia was more prevalent in the age group of 21 years with 13 students (41.9%), and in females with 24 students (77.4%). Myopia was found to be high in students with a family history of myopia with 17 students (56.4%). In conclusion, the highest incidence of myopia is found in individuals with low myopia, female, 21 years of age, and a family history of myopia.
Keywords: myopia; degree of myopia; age; sex; family history
 
Abstrak: Miopia adalah suatu kelainan dimana cahaya yang masuk ke mata difokuskan di depan retina sehingga objek yang jauh terlihat buram. Prevalensi miopia mengalami peningkatan pesat baik pada anak maupun dewasa yang menjadi tantangan bagi kualitas hidup masyarakat. Jika tidak tangani, myopia dapat menyebabkan komplikasi serius bahkan kebutaan. Penelitian ini bertujuan untuk mengetahui gambaran kejadian miopia pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ialah deskriptif kuantitatif dengan desain potong lintang. Subjek penelitian ialah mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi yang menderita miopa diambil dengan teknik purposive sampling. Hasil penelitian ini menunjukkan jumlah subjek yang menderita miopia ialah 31 mahasiswa; 26 mahasiswa (83,9%) memiliki derajat ringan. Miopia lebih banyak terjadi pada usia 21 tahun dengan jumlah 13 mahasiswa (41,9%). Kejadian miopia ditemukan paling banyak pada perempuan sebanyak 24 mahasiswa (77,4%). Kejadian miopia ditemukan tinggi pada mahasiswa dengan riwayat keluarga miopia, yakni 17 mahasiswa (56,4%). Simpulan penelitian ini ialah kejadian miopia tertinggi didapatkan pada miopia derajat ringan, jenis kelamin perempuan, usia 21 tahun, dan memiliki riwayat keluarga dengan miopia.
Kata kunci: miopia; derajat miopia; usia; jenis kelamin; riwayat keluarga
Application of Exponential and Logistic Models in Estimating the Population of Bulukumba Regency in 2020-2030
Authors: Sulma Sulma , Nursamsi Nursamsi
Published: July 2024

Population data is useful as planning material in making various policies, including avoiding imbalances between the number of health facilities and services and the population in an area as well as other facilities such as schools, markets, and other public facilities. Ordinary differential equations of exponential and logistic models are used in modeling population dynamics in Bulukumba Regency to obtain population estimates until 2030. The determination of the future population of Bulukumba Regency is based on the growth rate and capacity obtained using the exponential and logistic approaches. The results obtained show that the estimation using the exponential model and the logistic model estimation for 2015-2019 are close to the data from the Central Bureau of Statistics. However, the logistic model is more accurate than the exponential model which is more significantly close to the data from BPS. So that the results of the logistic model are better than the exponential. The logistic model assumes that Bulukumba Regency has a capacity of K = 450000, while the exponential model assumes that the population increases exponentially.
ASSESSING SERUM C-REACTIVE PROTEIN AND LACTATE DEHYDROGENASE AS HEMOTOXICITY INDICATORS IN PATIENTS WITH VASCULOTOXIC SNAKEBITES
Authors: Choudhary Ratan , patil Ravi , Dandekar Vandana
Published: July 2024

Background : Snakebites are a signicant public health issue, particularly in tropical regions, with a
focus on South Asia. It emphasizes the high incidence of snakebites among rural populations and the
challenges of underreporting and underestimation of the problem. The study highlights the diversity of venomous snakes,
particularly in India, and the various effects of snake envenomation on different body systems, emphasizing the importance of
swift diagnosis and treatment. This study aims to investigate the potential of serum C-reactive protein (CRP) and lactate
dehydrogenase (LDH) as markers of hemotoxicity in snakebite cases. Methods: This was a prospective observational study
conducted at MGM Medical College, Navi Mumbai, India, from March 2021 to December 2022 and included 70 snakebite
cases. using convenient sampling. Results: Majority of the subjects were female (81.4%) within the 21-40 age group, with lower
limb snakebites being common, and most patients seeking medical attention within 6 hours. Envenomation severity ranged
from none to severe, and 37.1% of subjects exhibited bleeding manifestations. Variations in CRP and LDH levels were
associated to envenomation severity. Patients with bleeding manifestations displayed signicant increases in CRP and LDH
levels over 24 hours, indicating inammation and cellular damage associated with bleeding. Receiver operating characteristic
(ROC) curve analysis identied CRP and LDH at 24 hours as moderate predictive biomarkers for bleeding manifestations, with
optimal cut- off values of CRP > 5 mg/L and LDH > 300 U/L. Conclusion: Serum CRP and LDH levels demonstrated signicant
variations across envenomation grades, particularly elevated in severe cases, indicating their potential as hemotoxicity
markers in snakebite patients. These markers also aid in distinguishing severe from mild envenomation, facilitating early
assessment and management.
EXPLORING MINDFULNESS: HISTORICAL INSIGHTS AND PRACTICE TYPES
Authors: Bhatia Pooja , Kumar Prashant
Published: July 2024

Mindfulness, a practice rooted in ancient contemplative traditions, has garnered signicant attention in
contemporary psychological research for its potential benets on mental health and well-being. This
article offers a comprehensive overview of mindfulness, highlighting its historical context and the various practice types that
have been integrated into modern clinical settings. We trace the origins of mindfulness from its beginnings in Buddhist
meditation to its adaptation within Western psychological frameworks.
FUNGAL PROFILE OF CLINICAL SPECIMENS FROM A TERTIARY CARE HOSPITAL – A RETROSPECTIVE STUDY.
Authors: Sarkar Kristi , Mullan Summaiya
Published: July 2024

- Fungal infections are emerging as one of the most dreaded groups of infectious diseases
with serious morbidity and mortality. Advanced therapeutics, the use of invasive devices, irrational use of
broad spectrum antimicrobials and other environmental changes have resulted in an alarming increase in fungal diseases.
Studies related to epidemiology, and distribution patterns across various geographical areas are distinct and different and
the actual picture is still unclear. Hence, understanding the spectrum of fungal isolates recovered from clinical specimens will
aid in effective management and control of these infections, ultimately improving patient outcomes and reducing the burden of
fungal diseases in hospital settings. Materials and Methods- A retrospective study was conducted in the Microbiology
Department of Government Medical College, Surat from January 2023 to December 2023. All the samples that were received in
the microbiology laboratory for fungal culture and sensitivity testing was processed using standard microbiological guidelines
for isolation of yeast and mold. Susceptibility testing of different yeast species to available antifungal agents was performed by
using standard guidelines by disc diffusion method as per standard guidelines. Results – Out of a total of 2767 samples
received during study period, 221 fungal isolates were grown in the laboratory after standard processing. Non-candida
albicans were most predominant (48%) which constituted species like Candida tropicalis, Candida krusei, Candida
parapsilosis, etc. Invasive fungal infections were caused by Non-candida albicans, especially Candida tropicalis followed by
Candida krusei. Higher resistance to tested azole agents was seen among yeast isolates retrieved from Intensive care units.
Conclusion -Since fungal diseases exhibit signicant geographical variations, it is critical to ascertain the local pattern of
etiology and other essential parameters of a specic place or institute to aid in future management strategies.
STUDY TO ASSESS THE EFFECT OF STRUCTURED TEACHING PROGRAMME ON ILL-EFFECTS OF CIGARETTE SMOKING AMONG ADOLESCENT BOYS IN SELECTED GOVERNMENT SCHOOL IN THIRUVANANTHAPURAM DISTRICT, KERALA.
Authors: Liza Liza , Christopher Lilly
Published: July 2024

Introduction: Cigarette smoking among adolescents remains a major public health concern given the
frequent persistence of this behavior into adulthood (Colditz & Hunter 2000). WHO estimates that unless
the current smoking pattern is reversed, tobacco will be responsible for 10 million deaths per year by the decade 2020–2030,
with 70% of them occurring in developing countries. (WHO 2007, 2) Adolescents should have knowledge and awareness of the
ill-effects of cigarette smoking, which play an important role in preventing the diseases. Objectives: 1) To assess the pre-test
knowledge score regarding the ill-effects of cigarette smoking among adolescents. 2) To assess the post-test knowledge score
regarding the ill-effects of cigarette smoking among adolescents. 3) To compare the pre-test and post-test knowledge scores
regarding the ill-effects of cigarette smoking among adolescents. 4) To nd the association between the pre-test knowledge
score and selected demographic variables among adolescents. Material And Methods: A quantitative approach and Quasi
experimental one group pre-test post-test design were used for this study. The study was conducted among 60 adolescent boys
at Govt. High School, Perumpazhuthoor. A non-randomized purposive sampling technique was used for this study. The tool
consists of two parts. Section I: demographic variables; and Section II: self-administered knowledge questionnaire. Result:
The ndings in the present study revealed that the paired t value computed at 17.47 (df = 59) by comparison of the mean pre-test
and post-test knowledge scores (10.33 + 4.13, 16.55 + 2.94) was statistically signicant at P< 0.05. The above results revealed
that there was a signicant difference between pre-test and post-test scores among high school children after a structured
teaching program. Conclusion: The high school children had gained knowledge on the ill-effects of smoking after a structured
teaching program in the post test assessment. The mean pre-test and post-test knowledge scores (10.33 + 4.13, 16.55 + 2.94)
were statistically signicant at P< 0.05.
COMPARATIVE ANALYSIS OF MENTAL TOUGHNESS AND ACHIEVEMENT MOTIVATION BETWEEN SHELTER HOME AND HOMEBOUND ADOLESCENTS
Authors: Yadav Renu , Verma Abhishek
Published: July 2024

Adolescence, a critical developmental stage, signicantly impacts an individual's mental toughness and
achievement motivation, key factors in navigating academic, social, and personal challenges. This study
investigates these traits among adolescents from shelter homes and traditional home environments in Varanasi, Uttar Pradesh.
Utilizing Alan Goldberg's Mental Toughness Questionnaire and M.L. Kamlesh's Achievement Motivation Questionnaire, data
were collected from 100 adolescents (50 from each environment, equally divided by gender, aged 14-18 years). The study
employed an independent samples t-test to compare the groups. Results indicated no signicant differences in mental
toughness and achievement motivation between shelter home and homebound boys (t-stat = 1.57, p = 0.12 for mental
toughness; t-stat = 1.72, p = 0.09 for achievement motivation). However, signicant differences were observed among girls, with
homebound girls exhibiting higher mental toughness (t-stat = 4.21, p < 0.05) and achievement motivation (t-stat = 3.05, p <
0.05) compared to their shelter home counterparts. These ndings emphasize the inuence of stable, supportive environments
on the psychological development of adolescents, particularly females, and highlight the necessity for targeted support
programs for those in shelter homes.
PERIPARTUM CARDIOMYOPATHY IN PREGNANT WOMEN PRESENTING WITH DYSPNEA
Authors: R. Megha , L Dwarkanath , H. Indira , B L. Girish
Published: July 2024

Aims and Background: Peripartum cardiomyopathy (PPCM) is a rare but potentially life threatening
form of cardiac failure with a high degree of morbidity and mortality. This study was aimed to screen the
pregnant women for PPCM, to ascertain the role of two dimensional (2D) echocardiography in the diagnosis of PPCM and to
identify important risk factors. Methods: This hospital based crosssectional study was done in the Department of Obstetrics
and gynaecology, Sri Siddhartha Medical College and Hospital, Tumakuru, Karnataka, India for the period of 18 months from
June 2022 to December 2023. A total of 116 women presenting with shortness of breath or other symptoms of PPCM were studied.
Results: Three women (2.59%) were diagnosed with PPCM among them, one women (0.86%) had peripartum and two women
(1.72%) had postpartum cardiomyopathy. Electrocardiogram (ECG) ndings revealed ST changes in two women (1.72%) and
one women (0.86%) had ST changes with T and V2 inversion. The 2D echo ndings revealed dilated left atrium/left ventricle (LV)
and left ventricular dysfunction (LVD), LV ejection fraction (LVEF)<45% in all the three women.During the study period there
were a total of 1381 live births and incidence of PPCM was one per 460 live births.The mean age was 25.18±2.12 years. Most of
the women were housewives(63.79%), from rural locality (61.21%),had singleton pregnancy (99.14%), consumed mixed diet
(69.83%),belonged to lower middle class socioeconomic strata(37.07%), primi para (56.90%). Conclusion: Considerable
number of women are at risk of PPCM. Two dimensional echocardiography helps in early diagnosis of high-risk cases of PPCM.
Further, maternal age, fatigue, chest pain, gestational age and respiratory rate as important risk factors leading to PPCM.
PATERNAL ATTITUDE AND SUPPORT TOWARDS BREASTFEEDING AMONG FIRST-TIME MOTHERS IN A TERTIARY CARE CENTER
Authors: Sahoo Swati , Pradhan Janaki Ballav , Swain Suryakanta , Parida Darshan
Published: July 2024

Introduction:A neonatal first natural food is mother `s milk that provides the energy and nutrients required to sustain
initial few months of life.Initiating and sustaining breastfeeding is the most important.Research on breastfeeding mostly
investigate maternal factors.Hence,this study aimed to determine the associations of father's attitude and support with
the duration of exclusive breastfeeding among new parents. Methods: The study involved 100 new parents in hi tech
medical college, Bhubaneswar Odisha who were admitted in postnatal ward. Parents were interviewed using pre
structured questionnaire within 48hours of delivery of their first child. Fathers' breastfeeding attitude was measured
using Iowa-Infant-Feeding-Attitude-Scale, whereas paternal support using Subjective Norms and PaternalBreastfeeding-Influence-Scale questionnaires. Mothers were asked about breastfeeding practice. Results: Exclusive
breastfeeding duration rates at six months was 35%.Whereas 38% and 35% of fathers had knowledge of colostrum
feeding and timing of first feed initiation respectively. The average score for paternal attitude on breastfeeding was 56.0
±6.3,indicating father's positive attitude towards breastfeeding.The mean score of paternal breastfeeding supports for
subjective norms surrounding breastfeeding and overall support score were 4.3+0.6 and 4.06+0.6, respectively,
demonstrating frequent paternal engaging and support in breastfeeding. Duration of exclusive breastfeeding were
positively associated with the paternal attitude ( =0.23, p=0.027) and overall mean score for breastfeeding support
( =2.046,p=0.032),but negatively associated with support strategies score ( = -2.203,p=0.026).Conclusion: Overall,
paternal support and positive attitude were associated with breastfeeding duration. It is important to increase public
awareness on the important roles of fathers during the breastfeeding process. This will go a long way in decreasing
malnutrition,morbidity and mortality in children
EXPLORING FARMERS' PARTICIPATION IN CROP INSURANCE SCHEMES: A COMPARATIVE ANALYSIS OF SMALL AND MARGINAL FARMERS
Authors: P B Rudramuni , Venkatesh S.
Published: July 2024

Crop insurance schemes play a critical role in mitigating agricultural risks, yet the participation of small and marginal
farmers remains disproportionately low.This research paper investigates the participation patterns of small, marginal,
and other farmers in crop insurance schemes,focusing on the Pradhan Mantri Fasal Bima Yojana (PMFBY) in India.Using
data spanning six years from 2018 to 2023, collected from the PMFBY website, the study employs descriptive statistics
and Compound Annual Growth Rate (CAGR) analysis to explore participation trends,variability,and distribution among
different categories of farmers during both Kharif and Rabi seasons. Findings reveal a troubling trend of declining
participation across all farmer categories,accompanied by notable variability and skewed distribution in participation
levels. Recommendations include targeted interventions to incentivize marginal farmers, address declining
participation among small farmers and others, manage variability and distribution, empower small farmers through
capacity building, and implement consistent monitoring and evaluation practices.The study underscores the need for
comprehensive policy measures to achieve inclusive and sustainable agricultural development by addressing
participation disparities among farmers in crop insurance schemes.
A RARE OCCURRENCE OF ANTROCHOANAL POLYP IN PEDIATRIC AGE GROUP FIVE YEARS
Authors: Soni Sheetal , Siddiqui Yasmeen , Ashraf Mohammad
Published: July 2024

Antrochonal polyp is a benign solitary sino nasal polyp
arising within the maxillary sinus and extending into
nasopharynx via sinus ostium. It is commomly reported in
rd th young adults mainly in 3 to 4 decades . Antrochoanal polyp
accounts 4% to 6% sinonasal polyp in general population and
approximately 33% in pediatric population. Here we are
reporting a case of antrochoanal polyp in just five year old
because of its relative rarity