bluuebunny/crossref_metadata_2025 huggingface dataset:
Lethal cases of lyssavirus encephalitis in humans after contact with bats in the Russian Far East in 2019–2021
Authors: Poleshchuk E. M. , Tagakova D. N. , Sidorov G. N. , Orlova T. S. , Gordeiko N. S. , Kaisarov A. Zh.
Published: March 2023

Introduction. On the territory of Russia four species of lyssaviruses (genus Lyssavirus) were identified, three of them caused human deaths.
The aim of work: to characterize fatal cases in humans after contacts with bats in the Far East in 20182021 and to perform typing of isolated pathogens.
Materials and methods. Lyssavirus infection was confirmed in samples of sectional material from people who died in the Amur Region in 2019, in the Primorsky Krai in 2019 and 2021. Diagnostics was performed by fluorescent antibody test (FAT) and RT-PCR using diagnostic kits of domestic production. Viruses were isolated in a bioassay. The nucleoprotein sequences were analyzed after 1st passage. The analysis of phylogenetic relationships and the construction of a dendrogram were performed using the MEGA7 software.
Results. The viruses that caused the fatal cases in humans in the Amur Region and Primorsky Krai share more than 90% identity to Lyssavirus irkut detected in Russia and China. Together they form a separate monophyletic cluster with 100% bootstrap support.
Conclusion. On the territory of Russia, monitoring of bat populations for infection with lyssaviruses is relevant. The material of people who died from encephalomyelitis of unknown etiology within 1015 days from the onset of the disease must be examined for lyssavirus infection. It is necessary to develop PCR assays that employ genus-specific primers. The use of molecular biological methods is promising for improving the diagnosis of rabies and epidemiological surveillance, as well as increasing the efficiency of the system of biological safety of the population of the Russian Federation.
Shrew-borne hantaviruses (Hantaviridae: Orthohantavirus) in the Far East of Russia
Authors: Yashina L. N. , Ivanov L. I. , Kompanets G. G. , Zdanovskaya N. I. , Kartashov M. Yu.
Published: March 2023

Introduction. Insectivores are newly recognized hantaviral reservoir worldwide. Four distinct shrew-borne hantaviruses (family Hantaviridae) have been identified in two regions located in southern and northern part of the Russian Far East, two genetic variants of Seewis virus (SWSV), Lena River virus (LENV), Kenkeme virus (KKMV) and Yakeshi virus (YKSV). Here, we describe geographic distribution of shrew-borne hantaviruses in southern part of the Russian Far East: Jewish Autonomous region, Khabarovsk Krai, Primorsky Krai and Sakhalin region.
Materials and methods. Lung samples from shrews of genus Sorex, captured in the four regions of Far Eastern Russia, were examined for hantavirus RNA using reverse transcription polymerase chain reaction (RT-PCR). Phylogenetic analysis of the partial nucleotide sequences of viral genome was conducted using MEGA X software.
Results. New genetic variant of YKSV was identified in new reservoir host, long-clawed shrew (S. ungiuculatus) from Sakhalin Island. Genetic variant of SWSV, ARTV-Sc, has been found to circulate among S. caecutiens on the seacoast of Khabarovsk and Primorsky Krai. KKMV virus and second genetic variant of SWSV, ARTV-St, were found in S. roboratus and S. tundrensis, respectively from Jewish Autonomous region.
Conclusion. Sorex-borne hantaviruses were found in all studied regions of Far Eastern Russia. Our results demonstrated co-evolution of SWSV, KKMV, and YKSV viruses throughout the geographic distribution of its hosts.
Tinjauan Pengelolaan Sampah Dengan Sistem Reduce, Reuse, Recycle Dan Replace Di Desa Sampun Dusun 2 Kecamatan Dolat Rayat Kabupaten Karo Tahun 2022
Authors: Tanjung Nelson , Br Sembiring Kiki Aprina , Auliani Restu , Rusli Mustar , Manik Erba Kalto
Published: March 2023

Berdasarkan data Kementrian Lingkungan Hidup dan Kehutanan capaian volume sampah pada tahun 2021 yang terdiri dari 235 kabupaten/kota di indonesia bahwa timbulan sampah 26,739,004.66 ton/tahun. Pengelolaan sampah dengan sistem Reduce, Reuse, Recycle dan Replace menjadi pilihan pengelolaan sampah untuk menurunkan volume sampah. Penelitian ini bersifat deskriptif, populasi jumlah warga di desa sampun dusun 2 sekitar 540 warga dengan sampel 84 warga yang diambil secara simple random sampling. Hasil penelitian menunjukan pengelolaan sampah dengan sistem reduce (sering 22.38%, kadang-kadang 29.04% dan tidak pernah 48.57%), reuse (sering 18.80%, kadang-kadang 9.76% dan tidak pernah 56.90%), recycle (sering 18.33%, kadang-kadang 27.61% dan tidak pernah 65.95%) dan replace (sering 40%, kadang-kadang 28.57% dan tidak pernah 31.43%). Disarankan kepada warga tidak menimbun sampah, tidak membakar sampah dan tidak membuang sampah ke jurang. Sebaiknya pemerintahan di desa sampun menyediakan tong sampah kepada warga agar warga tidak membuang sampah ke jurang, pemerintahan di kecamatan dolat rayat memberikan truk pengangkut sampah sehingga sampah terkelola dengan baik dan juga bekerja sama dengan dinas lingkungan hidup agar dinas lingkungan hidup membuat penyuluhan pengelolaan sampah dan membuat pelatihan pengelolaan sampah secara Reduce, Reuse, Recycle dan Replace.
Risk Factors Associated with 28-Day Mortality of COVID-19 Patients at RSUP Dr. M. Djamil Padang
Authors: Arda Lusi Agustini , Khairsyaf Oea , Russilawati Russilawati , Handayani Tuti
Published: March 2023

Background: The COVID-19 mortality rate varies widely around the world. The COVID-19 death rate in Indonesia is currently relatively higher than the world average and is the highest in Southeast Asia. Data regarding risk factors of COVID-19 mortality in Indonesia, particularly West Sumatra, are still scarce. This study aims to determine the risk factors associated with the 28-day mortality of COVID-19 patients at RSUP Dr. M. Djamil Padang.Methods: This was an observational analytic study with a retrospective cohort approach on confirmed COVID-19 inpatients who were treated at RSUP Dr. M. Djamil Padang between January 1 and March 31, 2021. A bivariate analysis using Chi square was calculated to see the correlation between clinical severity, and routine blood values, markers of inflammation, liver function, kidney function, blood gas analysis, the RALE score and comorbidities with a 28-day mortality outcome. To assess the dominant risk factors, multivariate analysis was performed using logistic regression.Results: From 245 samples, patients aged >50 years and women were the most treated group of patients. Bivariate analysis obtained the following critical clinical grade factors: Hb <10 g/dl, leukocyte level >10.0x103/mm3, monocyte level 8.0%, procalcitonin level >0.5 ng/ml, interleukin-6 level >7 pg/ml, ferritin >159/ml, D-Dimer level >500 ng/dl, SGOT level >38 μ/l, urea >50 mg/dl, creatinine >1.3 mg/dl, PO2 <80 mmHg, SO2 ≤90%, PO2/FiO2 ≤300 mmHg, high RALE score, comorbid of chronic renal failure, hypertension, type II DM; and comorbidities >1 were associated with 28 days of death. Multivariate analysis identified critical clinical severity as the dominant risk factor (OR=8.47; 95% CI=2.55–28.14; P<0.001).Conclusion: Critical clinical severity was the dominant risk factor associated with the 28-day mortality of COVID-19 patients at RSUP Dr. M. Djamil.
Remdesivir in COVID-19: A Retrospective Analysis of Remdesivir Effectiveness and the Relation with Blood Type Variation
Authors: Purba Elsa Vera Denida , Andrajati Retnosari , Syafhan Nadia Farhanah , Wirawan Aditya
Published: March 2023

identify the profile of the effectiveness of Remdesivir (RDV) therapy and its relationship to blood type variations in COVID-19 patients at Universitas Indonesia Hospital (RSUI).Methods: Variations in blood types were examined for their influence on the effectiveness in Covid-19 infected patients with RDV as an antiviral treatment. Data for this study were acquired at RSUI using a retrospective cross-sectional method. The sample is infected patients with COVID-19 from January 2021 to December 2021 who received RDV therapy. The parameters of the effectiveness of the treatment was a reduction of minimally 2 points on the WHO Clinical Progression Scale after 14 days of Remdesivir administration.Results: RDV effectiveness percentage shows 57.5% of patients experienced clinical improvement. The analysis results of the effect of blood type variations on clinical outcomes significantly affect the effectiveness of RDV therapy (OR: 1.705, 95% CI: 1.091–2.665; p = 0.019) but insignificant in terms of mortality status (OR: 0.654, 95% CI: 0.383–1.117; p = 0.120).Conclusion: Blood type variations significantly affected the effectiveness of RDV therapy in infected COVID-19 patients.
p21 Genetic Modification as a Tumor-Suppressor Gene: A Future Target in Lung Cancer Therapy?
Authors: Wibowo Adityo , Saputri Silvana
Published: March 2023

Lung cancer is one of the most common cancers and the leading cause of cancer death worldwide. Although early diagnosis/screening methods and treatment strategies have developed, lung cancer patient survival rates remain low. However, resistance to chemotherapy and radiotherapy causes tumor recurrence and worsening of the disease, thus being the lead cause of treatment failure. In the growth cycle of lung cancer cells, the highest p21WAF1/CIP1 gene expression was found in early-stage lung cancer and decreased in advanced lung cancer. In addition, the association between CDK inhibitors and patient survival showed that inactivation of the p21WAF1/CIP1 and p16INK4a genes was associated with lower overall survival and poor prognosis. In this review, we will focus on the role of genetic modification in lincRNA-p21 in lung cancer therapy and the importance of a combination therapeutic approach.
Fayol’s Purpose Principles of Management: An Analysis of Practices of Heads at Secondary Level in District Poonch Azad Jammu & Kashmir, Pakistan
Authors: Anum Hayat  , Dr. Saira Nudrut  , Syed Jawad Zareen Shah
Published: March 2023

The study aimed to examine the managerial practices of school principals in district Poonch Azad Jammu & Kashmir's private secondary schools, using Henri Fayol's management theory's purpose principles as a framework. The primary goals of the study were to assess how the heads' experience impacted their adherence to Fayol's purpose principles and to compare the implementation of these principles based on gender. The research was founded on Henri Fayol's administrative theory. All the private schools were population of the study which was 94 during the academic year 2012-17. Systematic sampling technique adopted to select the sample. There 76 private schools selected as sample of the study. The data collected through questionnaires. This Instrument had been validated from the experts. Collected data had been entered in Statistical Package for Social Sciences (SPSS). This software supported the scholar for the generation of reports. For data analysis mean, ANNOVA and t-test used to find the relevant results of objectives. Results reported and derived on the basis of data analysis. Some key findings were that principles of Fayol management theory are practiced by heads. However some parts of this theory are being neglected. The implementation of these principles varies based on the previous experience of the team leads. In certain cases, highly experienced individuals may overlook principles that are crucial for those with less experience. The implementation of management principles also varies among leaders based on gender. Based on these variations in results, it is recommended that different performance reviews be provided to the school heads to assess their strengths and weaknesses. In addition, school heads may benefit from proper training sessions and mentoring. It is also suggested that workshops be conducted to raise awareness about management theories
Planning and Execution of the Library's use of Barcode Technology
Authors: - J.S. Vinuta , - Narmada Bhat
Published: March 2023

Aim: The main aim of this research paper is to create consciousness among the librarians to use Barcode technology in the library.
Design: This research paper briefly converses the explanation of the application of Barcode technology in libraries, advantages and its working mechanism. It also tried to discover the technical features of Barcode technology in the library.
Findings: Barcode technology is mostly used in the motion system of a library and most successful due to its speed, accuracy and reliability. Though barcode is relatively an old technology but it is one of the important steps in library automation and is still not extensively used in libraries.
Value: Barcode is very cost-effective technology can be used by every library.
At the Margins: The Socially Excluded Third Gender People
Authors: - Hema Gandotra
Published: March 2023

On the streets of Indian villages one sometimes comes across an unusual sight of a group of closely shaven persons in female attire, singing and dancing, making overtures to the onlookers, cracking sexually charged jokes at men and making loud clapping sounds with their hands. To people these individuals may look very interesting and outlandish freaks of nature. Not because they sing and dance but because of their ambivalent physical appearance. They shave, smoke and talk like men but dress and behave in a more feminine way. On seeing them, one question which would immediately strike relates to who are these people, male or female? And if they are neither males nor females, then what? In the Indian society these peoples are popularly referred to as ‘Hijras’, ‘Khusras’, ‘Asexuals’, ‘Neutrals’, ‘Eunuchs’, etc. All the terms included in the nomenclature are used to describe the identity of these people who have one thing in common and perhaps the most decisive one that there is something wrong with their sexual organs. So one can say that, for years we have looked at Hijras, but never seen or understood them.
Daya Simpan Nugget Oncom Wortel (Ontel) Dan Peluangnya Sebagai Lauk Nabati
Authors: Nurdini Dahlia , Wijayanti Wiwit , Gledya Ribka
Published: March 2023

Penelitian ini bertujuan untuk mengolah oncom menjadi nugget yang disebut dengan Nugget Ontel (Nugget Oncom Wortel) untuk mengetahui lama penyimpanan Nugget Ontel terhadap aspek rasa, aroma, warna, tekstur, dan tingkat kesukaan secara keseluruhan. Penelitian dilakukan di Laboratorium Universitas M.H Thamrin. Metode penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan 4 level dan 2 kali replikasi. Berdasarkan hasil uji friedman menunjukkan bahwa ada pengaruh lama penyimpanan terhadap aspek rasa, aroma, warna, dan tekstur. Berdasarkan aspek rasa pada penyimpanan sampai dengan 5 minggu menunjukkan rasa oncom kurang nyata, aroma yang tidak beraroma oncom, dengan warna kuning kecoklatan dan tekstur yang empuk. Ada pengaruh lama penyimpanan terhadap tingkat kesukaan aspek warna dan tekstur. Tidak ada pengaruh terhadap tingkat kesukaan aspek rasa dan aroma. Tingkat kesukaan nugget ontel yang disimpan sampai dengan 5 minggu terhadap aspek rasa, warna, aroma,  tekstur, dan tingkat kesukaan secara keseluruhan berada pada tingkat suka. Berat satu penukar nugget ontel adalah 42 gr dengan bentuk 2 potong sebesar 7 cm x 2 cm x 2 cm. hasil uji mikroorganisme menunjukkan bahwa nugget ontel yang telah disimpan selama 5 minggu masih aman untuk dikonsumsi.
Faktor yang Mempengaruhi Kejadian Anemia pada Ibu Hamil di Wilayah Kerja Puskesmas Lembursitu Kota Sukabumi (Analisis Data Sekunder)
Authors: Nuraisyah Neneng , Agustin Ratih
Published: March 2023

Anemia pada kehamilan merupakan salah satu masalah nasional karena mencerminkan nilai kesejahteraan sosial ekonomi masyarakat dan pengaruhnya sangat besar terhadap kualitas sumber daya manusia. Anemia pada ibu hamil disebut potensial membahayakan ibu dan anak. Tujuan dari penelitian ini adalah untuk mengetahui faktor yang mempengaruhi kejadian anemia pada ibu hamil di wilayah kerja Puskesmas Lembursitu Kota Sukabumi tahun 2020. Penelitian ini bersifat observasional dengan pendekatan cross sectional, jumlah sampel sebesar 99 ibu hamil diambil menggunakan teknik simple random sampling. Data sekunder berasal dari buku kohort ibu hamil tahun 2020. Data dianalisis secara univariat dan bivariat dengan menggunakan uji chi square. Hasil penelitian menunjukkan ada hubungan bermakna antara status gizi berdasarkan Lila dengan kejadian anemia pada ibu hamil (p-value = 0,024) dengan nilai OR 4,900, artinya ibu dengan status gizi KEK mempunyai odds 4,9 kali lebih tinggi mengalami kejadian anemia pada ibu hamil dibandingkan dengan ibu yang status gizinya tidak KEK. Sedangkan variabel umur ibu hamil, umur kehamilan, paritas, tingkat pendidikan dan pekerjaan ibu tidak ada hubungan bermakna dengan kejadian anemia pada ibu hamil (p-value 0,05). Bagi Dinas Kesehatan perlu adanya upaya pencegahan anemia pada ibu hamil terutama pada ibu hamil dengan status gizi berdasarkan Lila termasuk kategori KEK (Kurang Energi Kronik).
Kepatuhan Penggunaan Alat Pelindung Diri (APD) Pekerja Penanganan Prasarana dan Sarana Umum (PPSU) : Studi Kasus di Jakarta Timur
Authors: Syamsu Firdaus
Published: March 2023

Salah satu upaya penanggulangan terjadinya kecelakaan kerja adalah dengan menggunakan Alat Pelindung Diri (APD). meski menggunakan APD merupakan metode terakhir dalam pengendalian bahaya ditempat kerja, namun upaya ini menjadi sangat penting untuk diperhatikan ketika metode-metode pengendalian teknis pengendalian secara administratif belum maksimal melindungi pekerja dari potensi bahaya. Tujuan penelitian untuk mengetahui kepatuhan penggunaan APD, faktor – faktor yang berhubungan dengan kepatuhan penggunaan APD dan faktor yang paling dominan berhubungan dengan kepatuhan penggunaan APD pada pekerja PPSU di Jakarta Timur. Penelitian ini menggunakan metode analitik observasional dengan desain penelitian cross sectional. Populasi pada penelitian ini adalah pekerja PPSU di 5 kecamatan di Kota Administrasi Jakarta Timur yaitu Kecamatan Kramat jati, Cipayung, Ciracas, Makasar, dan Pasar Rebo, dengan sampel sebesar 250 responden. Analisis data penelitian ini terdiri dari analisis univariat, analisis bivariat (chi square) dan analisis multivariat (regresi logistik). Hasil penelitian didapatkan 50,8% responden kurang baik dalam mematuhi penggunaan APD ketika berkerja dan 49,2% responden baik dalam mematuhi penggunaan APD ketika berkerja. Hasil analisis bivariat didapatkan faktor yang ada hubungan signifikan (p0,05) antara kepatuhan penggunaan APD pada pekerja PPSU adalah faktor pengetahuan (p-value 0,023), faktor dorongan rekan kerja (p-value 0,032), dan faktor sikap (p-value 0,033). Hasil analisis multivariat didapatkan faktor paling dominan dengan kepatuhan penggunaan APD pada pekerja PPSU adalah faktor pengetahuan dan faktor sikap. Melakukan pelatihan Keselamatan dan Kesehatan Kerja (K3) secara berkala, memberikan arahan sebelum melakukan pekerjaan, meningkatkan pengawasan penggunaan APD pada pekerja, memperhatikan kelengkapan, ketersediaan, dan perawatan APD.
Edukasi Virtual Mengenai Hamil Sehat Tanpa Anemia Menggunakan Video Animasi
Authors: Rusmiati Desi
Published: March 2023

Anemia memang sering terjadi pada ibu hamil dan prevalensinyapun cukup tinggi di Indonesia yaitu mencapai 63,5%.Anemia mempengaruhi 58-80% wanita hamil dan tidak saja menjadi penyebab terjadinya volume besar pendarahan selama persalinan. Namun anemia dalam masa kehamilan juga dapat menyebabkan peningkatan kejadian bayi berat lahir rendah kelahiran prematur, serta menyebabkan ibu menjadi anemia pasca melahirkan. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan ibu hamil mengenai bahaya dan pencegahan anemia selama kehamilan, dengan demikian diharapkan ibu hamil dapat melalui masa kehamilannya dengan sehat tanpa anemia. Edukasi virtual ini dilakukan dengan membagikan video animasi berisi informasi mengenai bahaya anemia dan pencegahannya pada masa kehamilan, serta untuk melakukan evaluasi dilakukan pengukuran pengetahuan baik sebelum maupun setelah mendapatkan edukasi. Hasilnya skor pengetahuan ibu hamil sebelum mendapatkan edukasi adalah 6,5 dan setelah mendapatkan edukasi skor pengetahuan ibu menjadi 8,5. Edukasi virtual seperti halnya menggunakan media video animasi mampu meningkatkan pengetahuan ibu hamil, sehingga kegiatan pemberian edukasi dapat dilakukan secara virtual sehingga dapat menjangkau banyak audiens.
Penggunaan Media Audio Visual Dalam Upaya Meningkatkan Pemahaman Remaja Tentang Gizi dan Body Image Di SMA Negeri 8 Depok
Authors: Rusmiati Desi , Djaali Nur Asniati
Published: March 2023

Kelompok remaja menjadi salah satu penentu derajat kesehatan masyarakat sehingga mereka harus berada dalam status gizi yang baik. Permasalahan gizi yang terjadi pada remaja dapat ditangani salah satunya dengan cara memastikan bahwa kelompok remaja memiliki pengetahuan dan pemahaman yang baik tentang gizi dan body image. Tujuan dilakukan kegiatan ini adalah Meningkatkan pengetahuan dan pemahaman remaja tentang gizi, sedangkan secara khusus tujuan kegiatan ini adalah meningkatkan pengetahuan tentang asupan gizi dan status gizi, meningkatkan pemahaman tentang body image, dan menghasilkan media audio visual sebagai media promosi kesehatan yang tepat dalam upaya peningkatan pengetahuan remaja. Mitra dalam kegiatan ini adalah SMA Negeri 8 Depok yang berlokasi di Wilayah Depok berjarak 35 km dari Universitas mohammad Husni Thamrin, berdasarkan sertifikat nomor 02.00/308/BAP-SM/XI/2016, SMA Negeri 8 Depok memiliki akreditasi A. Solusi yang ditawarkan dalam kegiatan ini adalah melakukan penyuluhan terkait asupan gizi dan body image , dan mengembangkan media audiovisual sebagai mdia yang digunakan dalam melakukan penyuluhan. Dengan dilakukannya kegiatan ini diharapkan terjadi pemahaman yang baik tentang asupan gizi dan body image pada remaja sehingga dapat meningkatkan status gizi pada kelompok remaja.
Pemberdayaan Masyarakat Lanjut Usia dengan Akupresur Mandiri untuk Mengatasi Tekanan Darah Tinggi dan Meningkatkan Kualitas Hidup
Authors: Djaali Wahyuningsih , Viventius Yoshua , Lazuardi Didi , Mihardja Hasan , Rukmindar Dion , Mighra Bazzar Ari
Published: March 2023

Penyakit tekanan darah tinggi merupakan salah satu kondisi yang sering tidak terdeteksi dan dapat menyebabkan ganguan gangguan pada jantung hingga serangan stroke. Prevalensi kejadian hipertansi di Provinsi DKI Jakarta menurut data Riskesdas 2018 adalah sebesar 10,17%, di mana sebesar 24,04% didapatkan pada kelompok usia di atas 75 tahun. Kejadian hipertensi dalam jangka waktu yang lama dapat menyebabkan beberapa komplikasi seperti penyakit jantung dan stroke jika terjadi dalam jangka panjang, dan resiko ini lebih tinggi pada pasien berusia lanjut. Kondisi pandemi Covid-19 membuat kesempatan masyarakat untuk mendapatkan akses pelayanan kesehatan menjadi berkurang. Dibutuhkan suatu inovasi untuk melatih masyarakat agar dapat melalukan berbagai upaya untuk meningkatkan kesehatannya. Salah satu yang dapat dilakukan adalah dengan akupresur. Akupresur yang merupakan salah satu modalitas terapi akupunktur yang menggunakan penekanan dengan jari, berdasarkan beberapa penelitian telah terbukti efektif dalam menurunkan tekanan darah. Akupresur dapat dilakukan secara mandiri. Solusi dari permasalahan yang dapat dilakukan adalah dengan memberikan penyuluhan melalui seminar awam mengenai pencegahan hipertensi untuk mengurangi angka kejadian hipertensi dan perbaikan kualitas hidup, memberikan penyuluhan dan pelatihan kepada masyarakat khususnya masyarakat lansia, mengenai cara melakukan akupresur secara mandiri, dan membuat karya video edukasi akupresur mandiri untuk hipertensi pada lansia. Seminar awam dilakukan secara hybrid, yaitu secara offline dan online melalui Zoom. Seminar ini dihadiri oleh 50 orang peserta offline dan 940 orang peserta online. Dari 940 peserta yang hadir secara online, didapatkan hasil nilai pre-test dengan rerata 8,35 dari 940 peserta yang mengisi Google Form, dan didapatkan nilai post-test dengan rerata 9,31 dari 842 peserta yang mengisi Google Form. Dari hasil ini terlihat peningkatan rerata nilai yang menunjukkan meningkatnya pengetahuan peserta mengenai pencegahan hipertensi, pengertian dan manfaat akupresur, dan cara melakukan akupresur secara mandiri.
Peran Remaja Dalam Pencegahan Stunting (Kepedulian Remaja Investasi Generasi)
Authors: Wandini Kartika - , Angesti Annisa Nursita
Published: March 2023

Sebagai agen perubahan, remaja memiliki peran penting dalam pencegahan stunting. Untuk menjadi agen perubahan remaja perlu memahami penyebab, dampak, dan upaya yang dapat dilakukan untuk mencegah kejadian stunting yang di edukasi lewat program pengabdian masyarakat
Peningkatan Pengetahuan Tuberkulosis Pada Siswa di SMK Analis Kesehatan Kota Jakarta Timur
Authors: Fauziah Prima Nanda , Latifah Imas , Masdianto Masdianto , Zuraida Zuraida , Nurdiani Catu Umirestu
Published: March 2023

Tuberkulosis (TB) masih menjadi penyakit dengan jumlah penderita yang tinggi di Indonesia. Bakteri penyebab TB umumnya menyerang sistem pernapasan, namun dapat menyerang organ tubuh lainnya. Di kondisi saat ini, masalah COVID-19 yang melanda dunia termasuk Indonesia mengakibatkan penanggulangan dan target eliminasi TB di Indonesia menghadapi tantangan yang cukup berat. Dinas Provinsi DKI Jakarta menyebutkan pada tahun 2020, TB masih merupakan penyakit infeksi dengan jumlah penderita yang banyak. Persebaran terbanyak terdapat di Jakarta TimurÂ Â sebanyak 12.334 orang. Berdasarkan hasil penelitian yang dilakukan oleh pengusul pada tahun 2021 dengan judul Gambaran MikroskopisÂ Mycobacterium tuberculosisÂ pada Pasien TB, didapatkan bahwa pengetahuan pasien mengenai penyakit TB tergolong rendah yaitu 35%, dan berkorelasi dengan tingginya penularan TB. Kegiatan pengabdian kepada masyarakat ini merasa perlu dilakukan sebagai tindak lanjut dari hasil penelitian tersebut dengan melakukan upaya peningkatan pengetahuan tentang perkembangan dan pemeriksaan penyakit tuberkulosisÂ sedari dini di tingkat sekolah. Karena penderita TB usia anak dan remaja cukup banyak. Sekolah yang di pilih adalahÂ SMKÂ Jurusan Analis KesehatanÂ yang berlokasi di Jakarta Timur. Kegiatan dilakukan secara luring di Auditorium dr. Radjak Lantai 5 Kampus A Universitas Mohammad Husni Thamrin. Kegiatan ini diikuti oleh 89 peserta dari 100 peserta yang terdaftar.Â Â Simpulan, berdasarkan hasilÂ pre test, post testÂ dan antusias peserta yang mendaftar serta mengikuti seminar edukasi ini, maka kegiatan ini dapat menambah pengetahuan siswa dan siswi SMK Jurusan Analis Kesehatan terkait tuberkulosis dan perkembangan pemeriksaan terkini.Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Kata kunci:Â Eliminasi TB, kesehatan, peningkatan pengetahuan, tuberkulosis
The impact at recreation on settlement structure
Authors: Šprincová Stanislava
Published: March 2023

On the example of 177 settlements in the districts of Bruntál and Šumperk (North Moravia, Czechoslovakia) the author finds out the impact of recreation on the development of settlements of various largeness and of various types. She studies particularly some special signs of recreational (second) homing in marginal zones of towns (outskirts) and simultaneously she deals with interactions with the permanent housing, increasing very quickly nowadays. In the article she indicates also the prognosis of future development of second homing in the investigated area.
Prognosing in geography - its preparation for that task
Authors: Macka Miroslav
Published: March 2023

The author deals with the problems of prognosing in geography, especially in Czechoslovakia. According to his conclusion geography in socialist society ought to prefer the prognosis in areas of largest developing of socio-economic sphere. Economic geography has to examine and signal the consequences af intense economic activity on the natural environment; physical geography has to verify the progress of its own prognosis in a respective region or area.
To the erodological terminology
Authors: Zachar Dušan
Published: March 2023

The author deals with the basic erodologic term erosion and tries to define also some other related terms (denudation, transport, ablation, deluation, defflation, planing etc.). This paper ought to be a discussion to the problem provoked by the article of L. Loyda published in our Journal 83:4:258-265 (1978).
Folik Asitin Kanser Hücreleri Üzerine Etkisi ve Sitotoksisitelerinin Değerlendirilmesi
Authors: BALKİS Beyzanur , ÖZKAYA Serap , AYDEMİR Demir , DOĞRU Mehmet Ayberk , OLGUNER Cansu , AYDEMİR Esra
Published: March 2023

Folat ve folik asit, suda çözünen B vitaminin farklı formlarıdır. Folat, besinlerde doğal formda

bulunurken, folik asit ise vitamin takviyesi olarak B vitamininin sentetik formudur. Folat seviyesi yüksek

olan besinler arasında; yeşil yapraklı sebzeler ve kurubaklagil yer almaktadır. Folik asit, insan sağlığı

ve hastalığında önemli bir rol oynamaktadır. Folik asit eksikliği, nöral tüp defekti ve megaloblastik

aneminin yanı sıra kanser, kardiyovasküler hastalık ve zihinsel bozukluklarda da görülmektedir. Kanser

riski ve folat durumunun arasındaki ilişki folat için bilinen biyokimyasal mekanizmaların varlığıyla daha

da güçlendirilmiştir. Folat durumu, sağlıklı insanlarda kanseri önleyebileceği gibi pre-malign ve malign

lezyonların ilerlemesini de sağlayabilir. Bu da folik asitin karsinogenezde ikili bir rolü oynayabileceği

görüşünü desteklemektedir. Yapılan bu çalışmada MDA-MB-231, MCF-7 ve Vero hücrelerine uygulanan

folik asidin sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. İlaç 5,4,3,2,1 mg/ml, 600,400,100 μg/ml doz aralığında hücrelere uygulandı. İlaç uygulamasından sonra hücreler 24, 48 ve 72 saatlik sürelerde inkübasyona bırakıldı. İnkübasyon süresi sonunda yapılan testlerden elde edilen verilere göre sonuçlar değerlendirildi. Sonuçlar folik asidin, MDA-MB-231, MCF- 7 ve Vero hücrelerinin çoğalması üzerinde arttırıcı bir etkiye sahip olduğuna işaret etmektedir .
Kitosan Katkılı Kızılçam (Pinus Brutia Ten, Pinaceae) Kozalağı Ekstraktlarının Antikanser Etkilerinin Araştırılması
Authors: ÖZKAYA Serap , BALKİS Beyzanur , ÖZÇELİK Dide Irmak , OLGUNER Cansu , ULUDAĞ Ramazan , AYDEMİR Esra
Published: March 2023

Kanser, genomdaki birçok mutasyonun birikimi ile ortaya çıkan sistemik bir hastalıktır. Kanser

hastalarında uygulanan birçok farklı tedavi yöntemi bulunmaktadır. Tedavi süreci içerisinde zamanla artan toksisite ve ilaç direnci ortaya çıkmakta ve tedavi başarısını sınırlandırmaktadır. Kanser tedavisindeki bu sınırlandırmaları aşmak için bitkisel ürünler ve sentetik türevleri tercih edilebilmektedir. Bu noktada, geleneksel tıpta günümüze kadar birçok hastalığın tedavisinde kullanılan Kore çamı (Pinus koraiensis) ve uzun zincirli polimer türevi olan kitinin yaklaşık olarak yarısının deasetile edilmesiyle oluşturulan kitosan göze çarpmaktadır . Bu çalışmada kızılçam (Pinus brutia Ten) kozalağı ekstraktının MCF-7, VERO ve HeLa hücreleri üzerinde 24, 48 ve 72 saatlik inkübasyonlar sonundaki etkileri incelenmiştir. Ekstraktlar hücrelere 400, 200, 100, 50 ve 25μg/mL dozlarda uygulanarak maruziyet süreleri sonunda WST-1 sitotoksisite testi analiz edilmiştir. Deney sonuçlarında kitosan katkılı yeşil kozalak ekstraktı 24 saatlik inkübasyon sonunda hücrelerde sitotoksik etki yaratmazken, ekstrakt için 48 saat sonunda IC50 değeri 252.3 μg/mL olarak hesaplanmıştır. 72 saat sonrasında ekstrakt için hesaplanan IC50 değeri 195.5μg/mL ‘dir. Kitosan ilaveli yeşil çam kozalağı ekstraktının HeLa hücrelerinde 24, 48 ve 72 saatlik inkübasyon sürelerinde IC50 değerleri sırasıyla 200.5 μg/mL, 221.9 μg/mL ve 352.3 μg/ml olarak hesaplanmıştır. Kitosan ilaveli siyah çam kozalağı ekstraktında HeLa hücrelerinde 24 ve 48 saatlik inkübasyonlarda IC50 değerleri sırasıyla 262.6 μg/mL ve 161.9 μg/mL olarak hesaplanmıştır .
Özel Yetenekli Öğrencilerin Eğitiminde Bilim ve Sanat Entegresi
Authors: SEVGEN ABACI Hilal , TÜZÜN Ümmüye Nur
Published: March 2023

Bu araştırmada özel yetenekli öğrencilerin öğretim ortamlarının zenginleştirilmesinde bilim

ve sanat entegresi ile onların modern atom teorisi temelinde atom kavram imajlarını, zihinsel

algılarını geliştirmek amaçlanmıştır. Araştırma, Ankara ilinde özel yetenekli öğrencilere

öğretim veren bir kurumda dokuz özel yetenekli öğrenci ile yürütülmüştür. Özel yetenekli

öğrenciler 14-17 yaş aralığındadır. Araştırma biri bilim biri sanat branşlarından olmak üzere iki

araştırmacı tarafından yürütülmüştür. Araştırmanın deseni durum çalışmasıdır. Özel yetenekli

öğrencilerin modern atom teorisi temelinde hidrojen ve helyum atomuna dair zihinsel algılarını

yani imajlarını resmettikleri ve çizimlerini açıkladıkları çalışma yaprakları, araştırmanın veri

toplama aracıdır. Uygulama sürecinde özel yetenekli öğrenciler seçtikleri bir bulutsunun makro

görüntüsüne bulutsusu atomlarının modern atom teorisi temelinde submikroskobik görüntüsünü

harmanlayarak resmetmişlerdir. Uygulama süreci bilimsel tartışma ile desteklenmiştir. Öğrencilerin

yapılandırdıkları resimlerin kompozisyonları, sanatsal yeterlik açısından değerlendirilmiştir.

Uygulama öncesi ve sonrası öğrencilerin atom imajları çalışma yapraklarıyla toplanıp içerik analizi

ile çözümlenmiştir. Çalışma sonucunda özel yetenekli öğrencilerin atom imajlarının modern atom

teorisi temelinde bilim ve sanat entegreli bir multidisipliner uygulama sürecinde iyileştirildiği

bulunmuştur.
Yavaş Şehir Olma Yolunda Bir Sahil Kasabası: Antalya-Kaş Örneği
Authors: UÇAR Gamze
Published: March 2023

“Yavaşlığın düzeyi anının yoğunluğuyla doğru orantılıdır; hızın düzeyi unutmanın yoğunluğuyla doğru
orantılıdır. Yavaşlık ile anımsama, hız ile unutma arasında gizli bir ilişki vardır. Bir şey anımsamak
isteyen kimse yürüyüşünü yavaşlatır. Buna karşılık, az önce yaşadığı kötü bir olayı unutmaya çalışan
insan elinde olmadan yürüyüşünü hızlandırır .” Milan Kundera
Küreselleşme toplumsal yaşamın her alanında kendini göstermektedir. Temel olarak sınırların ortadan
kalkması anlamındaki küreselleşme olgusu, neoliberalizmle birleşince tüketim toplumunu ortaya
çıkarmıştır. Bireyler bir anda kendilerini sonsuz bir tüketim döngüsünün içinde bulmuşlardır. Geleneksel
anlamda tüketim ihtiyaçlara yönelik yapılırken, modern ve postmo-dern dönemde yerini isteklere yönelik
tüketime bırakmıştır. Küresel dünyanın sakinleri kendilerini tükettikleriyle tanımlamakta ve burada
bireyler hazdan çok hıza odaklanmaktadır. Yaşamı yalnızca hıza indirgeyerek basitleştiren bu yaşam
tarzının ise sürdürülebilir olmadığı ortadadır. Ayrıca hızlı ve düzensiz kentleşme, yoğun nüfus artışı,
risk toplumunun getirdiği korkuyla birlikte ortaya çıkan ve özellikle pandemiyle birlikte hızla artan
kitlesel gıda üretimine duyulan kuş-ku sonucunda bu olumsuzlukları tersine çevirmeye yönelik alternatif
yavaş hareketleri de ortaya çıkmıştır. Yavaş hareketlerinin kentsel boyuttaki yansıması olan Cittaslow
felsefesi, yaşamın, yaşamaktan zevk alınacak bir hızda yaşanmasını savunmaktadır. Bu çalışmada
Antalya’nın diğer turizm beldelerinden farklı bir niteliğe sahip olan Kaş ilçesinin yavaş şehir olma
potansiyeli yerel halk ve yerel yönetim perspektifinden değerlendirilmiştir. Çalışmada nitel araştırma
yöntemi ve araştırma deseni olarak fenomenoloji deseni kullanılmıştır. Çalışma kapsamında dördü kadın
ve beşi erkek olmak üzere toplam dokuz katılımcıyla ve Kaş Belediye Başkanı ile yarı yapılandırıl-mış
form kullanılarak derinlemesine görüşmeler yapılmıştır. Görüşmeler betimsel analiz yöntemiyle analiz
edilmiştir. Katılımcıların verdiği cevaplar çerçevesinde genel temalar belirlenip, her temanın altında yer
alan kategoriler tespit edilmiştir. Araştırma bulgularından edinilen sonuçlara göre Kaş’ın sosyal profili
ve sahip oldukları imkanlara bakıldığında konsept olarak yavaş şehir olma potansiyeli taşıdığı ancak
geliştirilmesi gereken yönlerinin de azımsanmayacak düzeyde olduğu görülmektedir. Ayrıca özellikle
yerel halk ve yerel yönetim arasındaki iletişimsizlik bu durumu n gerçekleşebilmesini engellemektedir .
Specifics of normative approaches to small ships
Authors: Назаров А.Г.
Published: March 2023

Малые суда широко используются для отдыха, коммерческой деятельности, служебных целей и рыболовства и являются самостоятельной и многочисленной группой судов. Если говорить о нормативной практике, такие суда находятся в «серой зоне» международного регулирования и требования к ним в разных странах существенно отличаются. В работе анализируется само понятие малого судна исходя из определения длины, пассажировместимости, района плавания. Рассмотрена структура требований к малым судам различного назначения в ряде юрисдикций. Подчёркивается важность создания нормативных ниш малых судов для российского рынка, что позволит создать условия для кратного увеличения числа строящихся судов, в первую очередь для внутренних пассажирских перевозок. На основе выполненного анализа сформулированы предложения по корректировке отечественной нормативной базы.

Small ships are widely used for recreation, commercial activities, special purposes and fishing and are an independent and numerous group of vessels. Talking about regulatory practice, such vessels are in the "gray zone" of international regulation and the requirements for them differ significantly in different countries. The paper analyzes the very concept of a small ship based on the definition of length, passenger capacity, navigation area. The structure of requirements for small craft for various purposes in a number of jurisdictions is considered. The importance of creating regulatory niches for small ships for the Russian market is emphasized, which will create conditions for a multiple increase in the number of ships constructed, primarily for domestic passenger transportation. On the basis of the analysis performed, proposals for improvement the domestic regulatory documents have been formulated.
Applicability substantiation of the semi-empirical hydrofoils calculation method for predicting separation and transient phenomena
Authors: Ромадин Д.С. , Яковлев А.Ю.
Published: March 2023

Целью работы является тестирование разработанного ранее полуэмпирического метода расчета характеристик гидродинамических профилей в части моделирования ламинарно-турбулентного перехода и отрыва пограничного слоя. Полуэмпирический метод основан на расчете потенциального обтекания профиля с помощью метода граничных интегральных уравнений и моделировании пограничного слоя интегральным методом. В качестве эталонного решения используются результаты CFD расчета обтекания профиля NACA0018 с помощью RANSметода в пакете OpenFOAM. Дано описание способа построения сетки, проведена проверка сеточной сходимости. С помощью указанных методов проведены сопоставительные расчеты коэффициентов подъемной силы и сопротивления профиля в диапазоне докритических углов атаки при двух значениях числа Рейнольдса, показано их хорошее согласование. Далее проведено сопоставление величин толщины потери импульса, положения точки ламинарно-турбулентного перехода в пограничном слое на профиле и положение точки отрыва пограничного слоя. Подтверждена хорошая точность прогнозирования этих характеристик с помощью полуэмпирического расчетного метода.

The aim of the work is to test the previously developed semi-empirical method for calculating the characteristics of hydrofoil sections in terms of modeling the laminar-turbulent transition and boundary layer separation. The semi-empirical method is based on the calculation of the potential flow around the hydrofoil section using the boundary integral equations method and modeling of the boundary layer by the integral method. As a reference solution, the results of CFD calculation of flow around the NACA0018 hydrofoil sections using the RANS method in the OpenFOAM package are used. The description of the grid construction method is given, the grid convergence is checked. Comparative calculations of the hydrofoil section lift and drag coefficients in the range of subcritical angles of attack at two values of the Reynolds number were carried out by these methods. The good agreement of the results was shown. Further, the values of the momentum loss thickness, the position of the laminar-turbulent transition point in the boundary layer on the hydrofoil section and the position of the boundary layer separation point were compared. The good accuracy of predicting these characteristics using a semi-empirical calculation method has been confirmed.
Analysis of influence process combustion on convective heat transfer in cylinder of marine high speed diesel
Authors: Руднев Б.И. , Повалихина О.В.
Published: March 2023

При совершенствовании существующих математических моделей локального теплообмена в камере сгорания судовых высокооборотных дизелей до последнего времени считалось, что процесс сгорания топлива оказывает большое влияние на параметры конвективного теплообмена. Однако современные экспериментальные исследования показали, что это влияние незначительно. Величины экспериментальных конвективных тепловых потоков, полученных при работе судового высокооборотного дизеля на топливе и при «чистом» сжатии отличаются в среднем на 6 – 10%. Целью настоящей статьи является представление и обсуждение результатов анализа влияния процесса сгорания на конвективный теплообмен в цилиндре судового высокооборотного дизеля. Представленные в статье экспериментальные данные показывают, что формирование тепловой нагрузки цилиндропоршневой группы в период активного тепловыделения определяется в основном процессом радиационного теплообмена. Это дает проектантам и исследователям возможность создания математических моделей, описывающих процессы локального теплообмена в камере сгорания судовых высокооборотных дизелей с большей точностью и сокращения сроков экспериментальной доводки новых образцов.

For creation modern mathematical models of local heat transfer in marine high speed diesels combustion chamber now is consider that the process of combustion fuel determines large influence to parameters of convective heat transfer. Thus modern experimental investigations have indicated that influence is slightly meaning. Data of experimental convective heat fluxes given for operation marine high speed diesel in fuel and for undreamed compression in contrast to medium 6 – 10 per cent. Purpose this article is presentation and discussion of results analysis for influence combustion process on convective heat transfer in a cylinder marine high speed diesel. Experimental data reveal formation of thermal power cylinder piston details during active radiative heat transfer is determine in this article. Designers and researchers receive opportunity for creation mathematical models writing processes of local heat transfer in marine high speed diesels combustion chamber with high accuracy and decrease of experimental times for drive of modern samples.
Control of heat generation in cogeneration gas-turbine plants with regeneration at partial loads
Authors: Дологлонян А.В. , Матвеенко В.Т. , Клименко А.Г.
Published: March 2023

Предметом рассмотрения в статье является исследование влияния перепуска воздуха мимо регенератора на характеристики когенерационных газотурбинных установок с регенерацией теплоты на частичных нагрузках при генераторном режиме нагружения. Проведенные исследования показали, что относительная теплота, переданная на теплоснабжение, возрастает, а КПД установок падает с понижением относительного расхода воздуха через регенератор при любой нагрузке. Установлено, что для микрогазотурбинных установок (МГТУ) на базе простого цикла (ПЦ) с регенерацией теплоты (Р) относительная теплота, переданная на теплоснабжение, возрастает с понижением относительного расхода воздуха через регенератор и практически не зависит от относительной мощности, а для МГТУ на базе ПЦ с турбокомпрессорным утилизатором (ТКУ) и Р относительная теплота, переданная на теплоснабжение, возрастает с понижением относительного расхода воздуха через регенератор и снижается при уменьшении относительной мощности. Показано, что использование байпасирования воздуха мимо регенератора для МГТУ на базе ПЦ с ТКУ и Р целесообразно при нагрузках близких к номинальным, а для МГТУ на базе ПЦ с Р – во всем диапазоне нагружения. Определено, что на любом режиме эксплуатации МГТУ уменьшение расхода воздуха через регенератор приводит к возрастанию мощности, что необходимо учитывать в процессе регулирования.

The subject of consideration in the article is the study of the effect of air bypass past the regenerator on the characteristics of cogeneration gas turbine plants with regeneration at partial loads in the generator loading mode. The completed studies have shown that the relative heat transferred to heat supply increases, and the efficiency of the plants decreases with a decrease in the relative air flow through the regenerator at any load. It has been established that for micro-gas turbine plants (MGTP) based on a simple cycle (SC) with regeneration (R), the relative heat transferred to heat supply increases with a decrease in the relative air flow through the regenerator and practically does not depend on the relative power, and for MGTP based on PC with a turbocharger utilizer (TCU) and R, the relative heat transferred to heat supply increases with a decrease in the relative air flow through the regenerator and decreases with a decrease in the relative power. It is shown that the use of air bypass past the regenerator for MGTP based on SC with TCU and R is rational at loads close to nominal, and for MGTP based on SC with R – in the all loading range. It has been determined that in any mode of operation of the MGTP, a decrease in air flow through the regenerator leads to an increase in power, which must be taken into account in the regulation process.
Purification of hydrogen for reaction on low-temperature fuel elements of underwater vehicles
Authors: Дядик А.Н. , Маловик Д.С.
Published: March 2023

Статья посвящена вопросам удаления углекислого газа на подводных аппаратах, оснащенных энергетической установкой на основе низкотемпературных топливных элементов (ТЭ). С целью достижения данной задачи рассмотрены варианты удаления диоксида углерода из рабочего газа методами абсорбции и адсорбции. Установлено, что в качестве абсорбента может быть использована забортная вода благодаря высокой растворимости диоксида углерода. Получены зависимости на основе физико-химических процессов, имеющих место в объеме абсорбера. Установлено, что процесс абсорбции углекислого газа жидкостью происходит за счет разности концентраций углекислого газа в пузырьке и окружающей жидкости, по этой причине требуется определение поверхности массообмена, состоящей из суммы поверхностей всех газовых пузырьков в объеме абсорбера для определения эффективности абсорбера. Для повышения степени очистки водорода и его осушки после абсорбера может быть использована адсорбция цеолитами.

The article is devoted to the issues of carbon dioxide removal on underwater vehicles equipped with a power plant based on low-temperature fuel cells (FC). To achieve this goal, options for removing carbon dioxide from the working gas by absorption and adsorption methods are considered. It has been established that seawater can be used as an absorbent due to the high solubility of carbon dioxide. On the basis of physico-chemical processes occurring in the volume of the absorber, the dependences are obtained. It is established that the process of carbon dioxide absorption by a liquid occurs due to the difference in the concentrations of carbon dioxide in the bubble and the surrounding liquid, for this reason, it is necessary to determine the mass transfer surface consisting of the sum of the surfaces of all gas bubbles in the volume of the absorber to determine the effectiveness of the absorber. For increase the degree of purification of hydrogen and its drying after the absorber, adsorption with zeolites can be used.