bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 4 from PIK3CA/PTEN Mutations and Akt Activation As Markers of Sensitivity to Allosteric mTOR Inhibitors
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Do Kim-Anh , Sangai Takafumi , Adkins Farrell , Gonzalez-Angulo Ana Maria , Rashid Asif , Crosby Katherine , Dong Mei , Phan Alexandria T. , Wolff Robert A. , Gupta Sanjay , Mills Gordon B. , Yao James
Published: April 2023

PDF file - 82K
Supplementary Figure 4 from The Rectal Cancer microRNAome – microRNA Expression in Rectal Cancer and Matched Normal Mucosa
Authors: Gaedcke Jochen , Grade Marian , Camps Jordi , Søkilde Rolf , Kaczkowski Bogumil , Schetter Aaron J. , Difilippantonio Michael J. , Harris Curtis C. , Ghadimi B. Michael , Møller Søren , Beissbarth Tim , Ried Thomas , Litman Thomas
Published: April 2023

PDF file, 248K, miRNA networks identified by IPA based on miRNAs that are differentially regulated between tumor and mucosa.
Supplementary Figure 3 from The Rectal Cancer microRNAome – microRNA Expression in Rectal Cancer and Matched Normal Mucosa
Authors: Gaedcke Jochen , Grade Marian , Camps Jordi , Søkilde Rolf , Kaczkowski Bogumil , Schetter Aaron J. , Difilippantonio Michael J. , Harris Curtis C. , Ghadimi B. Michael , Møller Søren , Beissbarth Tim , Ried Thomas , Litman Thomas
Published: April 2023

PDF file, 165K, Little overlap between prediction algorithms.
Supplementary Table 1 from CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity
Authors: de Graan Anne-Joy M. , Elens Laure , Sprowl Jason A. , Sparreboom Alex , Friberg Lena E. , van der Holt Bronno , de Raaf Pleun J. , de Bruijn Peter , Engels Frederike K. , Eskens Ferry A.L.M. , Wiemer Erik A.C. , Verweij Jaap , Mathijssen Ron H.J. , van Schaik Ron H.N.
Published: April 2023

PDF file - 45K, Hardy Weinberg equilibrium.
Supplementary Figure 1 from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
Authors: Gupta Subash C. , Prasad Sahdeo , Sethumadhavan Dhanya R. , Nair Mangalam S. , Mo Yin-Yuan , Aggarwal Bharat B.
Published: April 2023

PDF file - 130K, Nimbolide is bioavailable in the plasma and colorectal tumor tissues of nude mice. A, HPLC chromatogram of pure nimbolide. B, HPLC chromatogram of nimbolide in plasma. C, HPLC chromatogram of nimbolide in tumor tissues.
Supplementary Figure 1 from CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity
Authors: de Graan Anne-Joy M. , Elens Laure , Sprowl Jason A. , Sparreboom Alex , Friberg Lena E. , van der Holt Bronno , de Raaf Pleun J. , de Bruijn Peter , Engels Frederike K. , Eskens Ferry A.L.M. , Wiemer Erik A.C. , Verweij Jaap , Mathijssen Ron H.J. , van Schaik Ron H.N.
Published: April 2023

PDF file - 244K, Amplification plot.
Supplementary Methods from Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence
Authors: Di Martino Maria T. , Leone Emanuela , Amodio Nicola , Foresta Umberto , Lionetti Marta , Pitari Maria R. , Cantafio Maria E. Gallo , Gullà Annamaria , Conforti Francesco , Morelli Eugenio , Tomaino Vera , Rossi Marco , Negrini Massimo , Ferrarini Manlio , Caraglia Michele , Shammas Masood A. , Munshi Nikhil C. , Anderson Kenneth C. , Neri Antonino , Tagliaferri Pierosandro , Tassone Pierfrancesco
Published: April 2023

PDF file - 164K, Cell culture methods, in vitro assays, in vivo models
Supplementary Figure B from Accelerated Tumor Growth Mediated by Sublytic Levels of Antibody-Induced Complement Activation Is Associated with Activation of the PI3K/AKT Survival Pathway
Authors: Wu Xiaohong , Ragupathi Govind , Panageas Katherine , Hong Feng , Livingston Philip O.
Published: April 2023

Supplementary Figure B - PDF file 42K, CHLA136Luc or H524 cells treated with Human sera Complement (HuC') or heat inactivated HuC'(De-HuC') with or without the mAbs (3F8, PGNX and R24) for overnight. De- HuC' was achieved by heating the human complement for 30 min at 56{degree sign}C. Plates were read 2-4hrs after WST-1 addition (1:10 ratio) at 415nm. Figures representing the percent change in cell growth calculated according to formula: (OD of mAb+HuC' or de-HuC' - OD of HuC' or de-HuC')/OD of HuC' or de-HuC') X 100
Supplementary Figures and Legends from USP8 Is a Novel Target for Overcoming Gefitinib Resistance in Lung Cancer
Authors: Byun Sanguine , Lee Sung-Young , Lee Jihoon , Jeong Chul-Ho , Farrand Lee , Lim Semi , Reddy Kanamata , Kim Ji Young , Lee Mee-Hyun , Lee Hyong Joo , Bode Ann M. , Won Lee Ki , Dong Zigang
Published: April 2023

Supplementary Figures and Legends - PDF file 2854K, Supplementary Figure 1. Effect of USP8 knockdown on cell viability Supplementary Figure 2. Effect of USP8 knockdown on EGFR wildtype cells and apoptosis of NSCLC and normal cells. Supplementary Figure 3. Effect of USP8 knockdown on mRNA levels of RTKs. Supplementary Figure 4. Effect of USP8 inhibitor treatment on apoptosis of NSCLC and normal cells. Supplementary Figure 5. Fluorescence Intensity Profiling Supplementary Figure 6. Effect of USP8 knockdown or an USP8 inhibitor on insulin receptor (IR) expression. Supplementary Figure 7. An USP8 inhibitor reduces ERKs and STAT3 phosphorylation levels in tumors
Supplementary Methods from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 175K
Supplementary Table 3 from Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non–Small Cell Lung Cancers
Authors: Heller Gerwin , Weinzierl Marlene , Noll Christian , Babinsky Valerie , Ziegler Barbara , Altenberger Corinna , Minichsdorfer Christoph , Lang György , Döme Balazs , End-Pfützenreuter Adelheid , Arns Britt-Madeleine , Grin Yuliya , Klepetko Walter , Zielinski Christoph C. , Zöchbauer-Müller Sabine
Published: April 2023

PDF file - 31K
Supplementary Figure 2 from Prolonged Inhibition of Glioblastoma Xenograft Initiation and Clonogenic Growth following In Vivo Notch Blockade
Authors: Chu Qian , Orr Brent A. , Semenkow Samantha , Bar Eli E. , Eberhart Charles G.
Published: April 2023

PDF file - 154K, Changes to vascular factors were assessed in the HSR-GBM1 XG2 xenografts.
Supplementary Table 1 from Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non–Small Cell Lung Cancers
Authors: Heller Gerwin , Weinzierl Marlene , Noll Christian , Babinsky Valerie , Ziegler Barbara , Altenberger Corinna , Minichsdorfer Christoph , Lang György , Döme Balazs , End-Pfützenreuter Adelheid , Arns Britt-Madeleine , Grin Yuliya , Klepetko Walter , Zielinski Christoph C. , Zöchbauer-Müller Sabine
Published: April 2023

PDF file - 30K
Supplementary Methods and Supplementary Table 1 from A Five-Gene Hedgehog Signature Developed as a Patient Preselection Tool for Hedgehog Inhibitor Therapy in Medulloblastoma
Authors: Shou Yaping , Robinson Douglas M. , Amakye Dereck D. , Rose Kristine L. , Cho Yoon-Jae , Ligon Keith L. , Sharp Thad , Haider Asifa S. , Bandaru Raj , Ando Yuichi , Geoerger Birgit , Doz François , Ashley David M. , Hargrave Darren R. , Casanova Michela , Tawbi Hussein A. , Rodon Jordi , Thomas Anne L. , Mita Alain C. , MacDonald Tobey J. , Kieran Mark W.
Published: April 2023

Supplementary Methods and Supplementary Table 1. The supplementary data file contains the supplemental methods section describing the source of the patient samples used in the initial validation of the five-gene signature assay and supplementary table 1 which lists the number of patients with MB with tumor samples assessed per the five-gene signature assay from each clinical study as a second validation set.
Supplementary Figure 1 from Early [18F]Fluorodeoxyglucose Positron Emission Tomography at Two Days of Gefitinib Treatment Predicts Clinical Outcome in Patients with Adenocarcinoma of the Lung
Authors: Takahashi Ryo , Hirata Haruhiko , Tachibana Isao , Shimosegawa Eku , Inoue Atsuo , Nagatomo Izumi , Takeda Yoshito , Kida Hiroshi , Goya Sho , Kijima Takashi , Yoshida Mitsuhiro , Kumagai Toru , Kumanogoh Atsushi , Okumura Meinoshin , Hatazawa Jun , Kawase Ichiro
Published: April 2023

PDF file - 64K
Supplementary Table from Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
Authors: Engelke Carl G. , Parsels Leslie A. , Qian Yushen , Zhang Qiang , Karnak David , Robertson Jordan R. , Tanska Daria M. , Wei Dongping , Davis Mary A. , Parsels Joshua D. , Zhao Lili , Greenson Joel K. , Lawrence Theodore S. , Maybaum Jonathan , Morgan Meredith A.
Published: April 2023

PDF file, 78K, Summary of radiosensitization by MK8776.
Supplementary Figure 1 from Combined Alloreactive CTL Cellular Therapy with Prodrug Activator Gene Therapy in a Model of Breast Cancer Metastatic to the Brain
Authors: Hickey Michelle J. , Malone Colin C. , Erickson Kate L. , Lin Amy , Soto Horacio , Ha Edward T. , Kamijima Shuichi , Inagaki Akihito , Takahashi Masamichi , Kato Yuki , Kasahara Noriyuki , Mueller Barbara M. , Kruse Carol A.
Published: April 2023

PDF file - 409K, Individual animal weights plotted over time for treatment groups shown in Figure 6.
Supplementary Tables from microRNA 223 Is Upregulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1
Authors: Streppel Mirte Mayke , Pai Shweta , Campbell Nathaniel R. , Hu Chaoxin , Yabuuchi Shinichi , Canto Marcia Irene , Wang Jean S. , Montgomery Elizabeth A. , Maitra Anirban
Published: April 2023

Supplementary Tables - PDF file 55K, This file contains supplementary tables S1, S2 and S3. Table S1: Literature‐based miR selection for qRT‐PCR validation in a chemo‐radiation na�ve EAC cohort. Two types of miRs were chosen; miRs that may play a role in the development of BE‐ND (BE‐miRs) and miRs that may be involved in the neoplastic progression of BE (Neo‐miRs). Table S2: Quantitative real‐time PCR primers used for the validation of the Illumina microarray results. Table S3: this table contains the microarray results on two biological replicate experiments in OE33 cells. Only the genes that were more than 1.5 fold lower expressed upon miR-223 transfection are listed in this table.
Supplementary Figure 5 from Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
Authors: Engelke Carl G. , Parsels Leslie A. , Qian Yushen , Zhang Qiang , Karnak David , Robertson Jordan R. , Tanska Daria M. , Wei Dongping , Davis Mary A. , Parsels Joshua D. , Zhao Lili , Greenson Joel K. , Lawrence Theodore S. , Maybaum Jonathan , Morgan Meredith A.
Published: April 2023

PDF file, 482K, Phosphorylated Chk1 (S345) in MiaPaCa-2 xenografts and small intestines.
Supplementary Figure 4 from Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
Authors: Engelke Carl G. , Parsels Leslie A. , Qian Yushen , Zhang Qiang , Karnak David , Robertson Jordan R. , Tanska Daria M. , Wei Dongping , Davis Mary A. , Parsels Joshua D. , Zhao Lili , Greenson Joel K. , Lawrence Theodore S. , Maybaum Jonathan , Morgan Meredith A.
Published: April 2023

PDF file, 116K, Animal weight during treatment with MK8776, gemcitabine, and radiation.
Supplementary Methods, Figure 3 from 2-(3-{1-Carboxy-5-[(6-[18F]Fluoro-Pyridine-3-Carbonyl)-Amino]-Pentyl}-Ureido)-Pentanedioic Acid, [18F]DCFPyL, a PSMA-Based PET Imaging Agent for Prostate Cancer
Authors: Chen Ying , Pullambhatla Mrudula , Foss Catherine A. , Byun Youngjoo , Nimmagadda Sridhar , Senthamizhchelvan Srinivasan , Sgouros George , Mease Ronnie C. , Pomper Martin G.
Published: April 2023

PDF file - 153K
Supplementary Table 5 from A Randomized, Multicenter, Placebo-Controlled Clinical Trial of Racotumomab-Alum Vaccine as Switch Maintenance Therapy in Advanced Non–Small Cell Lung Cancer Patients
Authors: Alfonso Sailyn , Valdés-Zayas Anet , Santiesteban Eduardo R. , Flores Yoanna I. , Areces Fernando , Hernández Maurenis , Viada Carmen E. , Mendoza Ivis C. , Guerra Pedro P. , García Elena , Ortiz Ramón A. , de la Torre Ana V. , Cepeda Meylán , Pérez Kirenia , Chong Eric , Hernández Ana María , Toledo Darien , González Zuyén , Mazorra Zaima , Crombet Tania , Pérez Rolando , Vázquez Ana María , Macías Amparo E.
Published: April 2023

PDF file - 137KB, Association of functional capacity of elicited anti-NeuGcGM3 antibodies with patient's survival.
Supplementary Figure 2 from A Randomized, Multicenter, Placebo-Controlled Clinical Trial of Racotumomab-Alum Vaccine as Switch Maintenance Therapy in Advanced Non–Small Cell Lung Cancer Patients
Authors: Alfonso Sailyn , Valdés-Zayas Anet , Santiesteban Eduardo R. , Flores Yoanna I. , Areces Fernando , Hernández Maurenis , Viada Carmen E. , Mendoza Ivis C. , Guerra Pedro P. , García Elena , Ortiz Ramón A. , de la Torre Ana V. , Cepeda Meylán , Pérez Kirenia , Chong Eric , Hernández Ana María , Toledo Darien , González Zuyén , Mazorra Zaima , Crombet Tania , Pérez Rolando , Vázquez Ana María , Macías Amparo E.
Published: April 2023

PDF file - 144KB, Overall survival HRs (racotumomab over placebo) in subgroups according to baseline characteristics.
Supplementary Figures 1 - 9 from Monoclonal Antibody against Cell Surface GRP78 as a Novel Agent in Suppressing PI3K/AKT Signaling, Tumor Growth, and Metastasis
Authors: Liu Ren , Li Xiuqing , Gao Wenming , Zhou Yue , Wey Shiuan , Mitra Satyajit K. , Krasnoperov Valery , Dong Dezheng , Liu Shuanglong , Li Dan , Zhu Genyuan , Louie Stan , Conti Peter S. , Li Zibo , Lee Amy S. , Gill Parkash S.
Published: April 2023

PDF file - 736K, Fig. S1. Generation and characterization of MAb159. Fig. S2. MAb159 induces GRP78 endocytosis through clathrin mediated pathway. Fig. S3. MAb159 induces apoptosis of tumor cells in vitro. Fig. S4. Surface GRP78 Forms Complex with PI3K. Fig. S5. Surface GRP78 level in cancer cell lines. Fig. S6. MAb159 treatment of xenograft tumor leads to reduced vessel density and mTOR signaling. Fig. S7. MAb159 shows no toxicity to normal organs in tumor xenograft study. Fig. S8. Inhibition of primary tumor growth and metastasis by MAb159 in 4T1 orthotopic model. Fig. S9. MAb159 inhibits the growth of hormone refractory mouse prostate cancer cell CE1 in vivo.
Data Supplement from PBX1 Is a Favorable Prognostic Biomarker as It Modulates 13-cis Retinoic Acid–Mediated Differentiation in Neuroblastoma
Authors: Shah Nilay , Wang Jianjun , Selich-Anderson Julia , Graham Garrett , Siddiqui Hasan , Li Xin , Khan Javed , Toretsky Jeffrey
Published: April 2023

Supplementary Figure 3. Longitudinal growth of PBX1-modulated cell lines, in complete media, for the given time points, up to 96 hrs for SK-N-RA cells and 192 hours for SK-N-SH, SK-N-BE(2), and SHSY5Y cells.
Data Supplement from PBX1 Is a Favorable Prognostic Biomarker as It Modulates 13-cis Retinoic Acid–Mediated Differentiation in Neuroblastoma
Authors: Shah Nilay , Wang Jianjun , Selich-Anderson Julia , Graham Garrett , Siddiqui Hasan , Li Xin , Khan Javed , Toretsky Jeffrey
Published: April 2023

Supplementary Figure 4: A) expression of PBX1 in high-risk tumors from 6A; B)EFS of patient set of 6B; C)Subset analysis of patient set in 6C, <18 months of age; D)Subset analysis of patient set in 6C, MYCN-nonamplified tumors.
Supplementary Figure 2 from A Phase I Weekly Dosing Study of Brentuximab Vedotin in Patients with Relapsed/Refractory CD30-Positive Hematologic Malignancies
Authors: Fanale Michelle A. , Forero-Torres Andres , Rosenblatt Joseph D. , Advani Ranjana H. , Franklin Anna R. , Kennedy Dana A. , Han Tae H. , Sievers Eric L. , Bartlett Nancy L.
Published: April 2023

PDF file - 67KB, Median duration of overall objective response and complete remission by Kaplan-Meier analysis.
Supplementary Figure 1 from A Phase I Weekly Dosing Study of Brentuximab Vedotin in Patients with Relapsed/Refractory CD30-Positive Hematologic Malignancies
Authors: Fanale Michelle A. , Forero-Torres Andres , Rosenblatt Joseph D. , Advani Ranjana H. , Franklin Anna R. , Kennedy Dana A. , Han Tae H. , Sievers Eric L. , Bartlett Nancy L.
Published: April 2023

PDF file - 76KB, Dose proportionality. (A) --- Area under the curve for brentuximab vedotin; (B) --- Area under the curve for free MMAE
Related Article from Model T Muscle CARs Can Treat Brain Tumors
Authors: Johnson Laura A.
Published: April 2023

Related Article from Model T Muscle CARs Can Treat Brain Tumors
Data Supplement from Expression of Androgen and Estrogen Signaling Components and Stem Cell Markers to Predict Cancer Progression and Cancer-Specific Survival in Patients with Metastatic Prostate Cancer
Authors: Fujimura Tetsuya , Takahashi Satoru , Urano Tomohiko , Takayama Kenichi , Sugihara Toru , Obinata Daisuke , Yamada Yuta , Kumagai Jimpei , Kume Haruki , Ouchi Yasuyoshi , Inoue Satoshi , Homma Yukio
Published: April 2023

Supplementary Figure S1. Correlation between mRNA expression and immunoreactivity of AR and Klf4.
Supplementary Table 2 from A Comparative and Integrative Approach Identifies ATPase Family, AAA Domain Containing 2 as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma
Authors: Fouret Robert , Laffaire Julien , Hofman Paul , Beau-Faller Michèle , Mazieres Julien , Validire Pierre , Girard Philippe , Camilleri-Bröet Sophie , Vaylet Fabien , Leroy-Ladurie François , Soria Jean-Charles , Fouret Pierre
Published: April 2023

PDF file, 63K, Enrichment q-values of ATAD2-associated modules in the LG cohort for cluster f genes, MYC target genes and GO term 'cell cycle process'.
Supplementary Table 1 from A Comparative and Integrative Approach Identifies ATPase Family, AAA Domain Containing 2 as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma
Authors: Fouret Robert , Laffaire Julien , Hofman Paul , Beau-Faller Michèle , Mazieres Julien , Validire Pierre , Girard Philippe , Camilleri-Bröet Sophie , Vaylet Fabien , Leroy-Ladurie François , Soria Jean-Charles , Fouret Pierre
Published: April 2023

PDF file, 44K, LitVAn significant terms for gene clusters f and i in the unsupervised analysis of gene expression.
Supplementary Table 1 from Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors
Authors: Moon Edmund K. , Wang Liang-Chuan , Dolfi Douglas V. , Wilson Caleph B. , Ranganathan Raghuveer , Sun Jing , Kapoor Veena , Scholler John , Puré Ellen , Milone Michael C. , June Carl H. , Riley James L. , Wherry E. John , Albelda Steven M.
Published: April 2023

PDF file - 38K, CAR TILs upregulate inhibitory receptors.
Supplementary Methods from Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors
Authors: Moon Edmund K. , Wang Liang-Chuan , Dolfi Douglas V. , Wilson Caleph B. , Ranganathan Raghuveer , Sun Jing , Kapoor Veena , Scholler John , Puré Ellen , Milone Michael C. , June Carl H. , Riley James L. , Wherry E. John , Albelda Steven M.
Published: April 2023

PDF file - 74K
Supplementary Figures 1 - 5 from Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors
Authors: Moon Edmund K. , Wang Liang-Chuan , Dolfi Douglas V. , Wilson Caleph B. , Ranganathan Raghuveer , Sun Jing , Kapoor Veena , Scholler John , Puré Ellen , Milone Michael C. , June Carl H. , Riley James L. , Wherry E. John , Albelda Steven M.
Published: April 2023

PDF file - 756K, Supplemental Fig 1. EMP and EMMESO mesothelin expression. Supplemental Fig 2. EMMESO flank tumors retain antigen expression in vivo. Supplemental Fig 3. MesoCAR TILs are unable to secrete IL-2 in response to antigen. Supplemental Fig 4. Supplemental IL-2 helps but is not necessary for CAR TIL recovery. Supplemental Fig 5. IFNγ and TNFα secretion by CAR TILs recovers after resting away from tumor.
Supplementary Figure 5 from Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV
Authors: Yoo Ji Young , Pradarelli Jason , Haseley Amy , Wojton Jeffrey , Kaka Azeem , Bratasz Anna , Alvarez-Breckenridge Christopher A. , Yu Jun-Ge , Powell Kimerly , Mazar Andrew P. , Teknos Theodoros N. , Chiocca E. Antonio , Glorioso Joseph C. , Old Matthew , Kaur Balveen
Published: April 2023

PDF file, 157K, Ex vivo serum rescue assay.
Supplementary Figure 2 from Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV
Authors: Yoo Ji Young , Pradarelli Jason , Haseley Amy , Wojton Jeffrey , Kaka Azeem , Bratasz Anna , Alvarez-Breckenridge Christopher A. , Yu Jun-Ge , Powell Kimerly , Mazar Andrew P. , Teknos Theodoros N. , Chiocca E. Antonio , Glorioso Joseph C. , Old Matthew , Kaur Balveen
Published: April 2023

PDF file, 96K, HSV-1 immuno stained sections of subcutaneous and intracranial tumors treated with PBS or ATN-224 (0.7mg) by daily gavage.
Supplementary Figure 3 from Pharmacokinetic and Pharmacodynamic Analysis of Circulating Biomarkers of Anti-NRP1, a Novel Antiangiogenesis Agent, in Two Phase I Trials in Patients with Advanced Solid Tumors
Authors: Xin Yan , Li Jessica , Wu Jenny , Kinard Rashell , Weekes Colin D. , Patnaik Amita , LoRusso Patricia , Brachmann Rainer , Tong Raymond K. , Yan Yibing , Watts Ryan , Bai Shuang , Hegde Priti S.
Published: April 2023

PDF file, 57K, Ratio of plasma PlGF or cNRP1 to baseline for each subject at all time points evaluated (Days 14, 21) from the Phase Ia study.
Supplementary Figure 1 from NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
Authors: Locke Jennifer A. , Zafarana Gaetano , Ishkanian Adrian S. , Milosevic Michael , Thoms John , Have Cherry L. , Malloff Chad A. , Lam Wan L. , Squire Jeremy A. , Pintilie Melania , Sykes Jenna , Ramnarine Varune Rohan , Meng Alice , Ahmed Omer , Jurisica Igor , van der Kwast Theo , Bristow Robert G.
Published: April 2023

PDF file - 41K, Univariate Kaplan-Meir plot of biochemical relapse-free rate of survival versus time to recurrence for patients who underwent IGRT with differential Prostate Stem Cell Antigen (PSCA) status is displayed. PSCA appears to be a significant prognosticator (Kaplan-Meier estimate bRFR 79% vs. 49%, p=0.0024).
Supplementary Tables 1-2 from Spinophilin Loss Correlates with Poor Patient Prognosis in Advanced Stages of Colon Carcinoma
Authors: Estevez-Garcia Purificacion , Lopez-Calderero Iker , Molina-Pinelo Sonia , Muñoz-Galvan Sandra , Salinas Ana , Gomez-Izquierdo Lourdes , Lucena-Cacace Antonio , Felipe-Abrio Blanca , Paz-Ares Luis , Garcia-Carbonero Rocio , Carnero Amancio
Published: April 2023

PDF file - 49K, Table 1: Clinical and pathologic features of patients in Cohort 1 (Stage II-III CRC); Table 2: Clinical and pathologic features of patients in Cohort 2 (stage IV CRC)
Supplementary Figure 1 from Spinophilin Loss Correlates with Poor Patient Prognosis in Advanced Stages of Colon Carcinoma
Authors: Estevez-Garcia Purificacion , Lopez-Calderero Iker , Molina-Pinelo Sonia , Muñoz-Galvan Sandra , Salinas Ana , Gomez-Izquierdo Lourdes , Lucena-Cacace Antonio , Felipe-Abrio Blanca , Paz-Ares Luis , Garcia-Carbonero Rocio , Carnero Amancio
Published: April 2023

PDF file - 77K, Hypermethylation analysis of Spn promoter in human CCR tumor samples
Supplementary Figure 1 from Targeting the PI3K Pathway in the Brain—Efficacy of a PI3K Inhibitor Optimized to Cross the Blood–Brain Barrier
Authors: Salphati Laurent , Heffron Timothy P. , Alicke Bruno , Nishimura Merry , Barck Kai , Carano Richard A. , Cheong Jonathan , Edgar Kyle A. , Greve Joan , Kharbanda Samir , Koeppen Hartmut , Lau Shari , Lee Leslie B. , Pang Jodie , Plise Emile G. , Pokorny Jenny L. , Reslan Hani Bou , Sarkaria Jann N. , Wallin Jeffrey J. , Zhang Xiaolin , Gould Stephen E. , Olivero Alan G. , Phillips Heidi S.
Published: April 2023

PDF file - 116K, Plot of CNS-MPO score vs. efflux ratio
Supplementary Tables 1 - 5 from Personalized Medicine in a Phase I Clinical Trials Program: The MD Anderson Cancer Center Initiative
Authors: Tsimberidou Apostolia-Maria , Iskander Nancy G. , Hong David S. , Wheler Jennifer J. , Falchook Gerald S. , Fu Siqing , Piha-Paul Sarina , Naing Aung , Janku Filip , Luthra Rajyalakshmi , Ye Yang , Wen Sijin , Berry Donald , Kurzrock Razelle
Published: April 2023

PDF file, 113K, Supplemental Table 1. List of clinical trials by ID number; Supplemental Table 2. Distribution of Molecular Aberrations by Diagnosis; Supplemental Table 3. Distribution of Molecular Aberrations by Diagnosis; Supplemental Table 4. Patient characteristics: tumor types by type of therapy; Supplemental Table 5 Response in patients with a RET mutation and in patients with a mutation other than RET by type of therapy (non-randomized).
Supplementary Figure Legend from Genome-Wide Somatic Copy Number Alterations in Low-Grade PanINs and IPMNs from Individuals with a Family History of Pancreatic Cancer
Authors: Hong Seung-Mo , Vincent Audrey , Kanda Mitsuro , Leclerc Julie , Omura Noriyuki , Borges Michael , Klein Alison P. , Canto Marcia Irene , Hruban Ralph H. , Goggins Michael
Published: April 2023

PDF file, 60KB.
CCR Translation for This Article from Design of a Phase III Clinical Trial with Prospective Biomarker Validation: SWOG S0819
Authors: Redman Mary W. , Crowley John J. , Herbst Roy S. , Hirsch Fred R. , Gandara David R.
Published: April 2023

CCR Translation for This Article from Design of a Phase III Clinical Trial with Prospective Biomarker Validation: SWOG S0819
Supplementary Figure 9 from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 72K, Supplemental Figure 9. Individual chromosome penetrance blots of BRAF/NRAS wild type conjunctival melanomas.
Supplementary Figure 6 from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 46K, Results of the NKp46 demethylation assay performed on HNSCC patient bloods stratified by date of blood draw relative to treatment
Supplementary Figure 5 from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 48K, Results of the NKp46 demethylation assay performed on HNSCC patient bloods stratified by tumor stage
Supplementary Figure 2 from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 46K, Comparison between NK cell level assessment by qMSP and fluorescence activated cell sorting (FACS)
Supplementary Figure 1 from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 60K, Bisulfite pyrosequencing of isolated human leukocytes
Supplementary Tables 1-2 from Chondrolectin Is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer
Authors: Masuda Ken , Takano Atsushi , Oshita Hideto , Akiyama Hirohiko , Tsuchiya Eiju , Kohno Nobuoki , Nakamura Yusuke , Daigo Yataro
Published: April 2023

PDF file - 49K
Supplementary Figure Legends 1-5 from Chondrolectin Is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer
Authors: Masuda Ken , Takano Atsushi , Oshita Hideto , Akiyama Hirohiko , Tsuchiya Eiju , Kohno Nobuoki , Nakamura Yusuke , Daigo Yataro
Published: April 2023

PDF file - 66K
Supplementary Figure Legend from ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Authors: Biddlestone-Thorpe Laura , Sajjad Muhammad , Rosenberg Elizabeth , Beckta Jason M. , Valerie Nicholas C.K. , Tokarz Mary , Adams Bret R. , Wagner Alison F. , Khalil Ashraf , Gilfor Donna , Golding Sarah E. , Deb Sumitra , Temesi David G. , Lau Alan , O'Connor Mark J. , Choe Kevin S. , Parada Luis F. , Lim Sang Kyun , Mukhopadhyay Nitai D. , Valerie Kristoffer
Published: April 2023

PDF file - 82K
Supplementary Figure 4 from ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Authors: Biddlestone-Thorpe Laura , Sajjad Muhammad , Rosenberg Elizabeth , Beckta Jason M. , Valerie Nicholas C.K. , Tokarz Mary , Adams Bret R. , Wagner Alison F. , Khalil Ashraf , Gilfor Donna , Golding Sarah E. , Deb Sumitra , Temesi David G. , Lau Alan , O'Connor Mark J. , Choe Kevin S. , Parada Luis F. , Lim Sang Kyun , Mukhopadhyay Nitai D. , Valerie Kristoffer
Published: April 2023

PDF File - 80K, KU-60019 administered by CED radiosensitizes U1242 tumors.
Supplementary Figure 2 from ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Authors: Biddlestone-Thorpe Laura , Sajjad Muhammad , Rosenberg Elizabeth , Beckta Jason M. , Valerie Nicholas C.K. , Tokarz Mary , Adams Bret R. , Wagner Alison F. , Khalil Ashraf , Gilfor Donna , Golding Sarah E. , Deb Sumitra , Temesi David G. , Lau Alan , O'Connor Mark J. , Choe Kevin S. , Parada Luis F. , Lim Sang Kyun , Mukhopadhyay Nitai D. , Valerie Kristoffer
Published: April 2023

PDF File - 80K, Surrogate dye show excellent distribution in the brain by osmotic pump delivery.
Supplementary Table 3 from A Pharmacodynamic/Pharmacokinetic Study of Ficlatuzumab in Patients with Advanced Solid Tumors and Liver Metastases
Authors: Tabernero Josep , Elez Maria Elena , Herranz Maria , Rico Isabel , Prudkin Ludmila , Andreu Jordi , Mateos Jose , Carreras Maria Josep , Han May , Gifford James , Credi Marc , Yin Wei , Agarwal Shefali , Komarnitsky Philip , Baselga Jose
Published: April 2023

PDF file - 54KB, Ficlatuzumab Study P05670. Post-baseline Versus Baseline Serum HGF Levels.
Supplementary Table 2 from A Pharmacodynamic/Pharmacokinetic Study of Ficlatuzumab in Patients with Advanced Solid Tumors and Liver Metastases
Authors: Tabernero Josep , Elez Maria Elena , Herranz Maria , Rico Isabel , Prudkin Ludmila , Andreu Jordi , Mateos Jose , Carreras Maria Josep , Han May , Gifford James , Credi Marc , Yin Wei , Agarwal Shefali , Komarnitsky Philip , Baselga Jose
Published: April 2023

PDF file - 45KB, Ficlatuzumab Study P05670. Summary of Pharmacodynamic Markers.
Supplementary Figure Legends from PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer
Authors: Khan Mohammad W. , Keshavarzian Ali , Gounaris Elias , Melson Joshua E. , Cheon Eric C. , Blatner Nichole R. , Chen Zongmin E. , Tsai Fu-Nien , Lee Goo , Ryu Hyunji , Barrett Terrence A. , Bentrem David J. , Beckhove Philipp , Khazaie Khashayarsha
Published: April 2023

PDF file - 74K
Supplementary data from A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer
Authors: Eustace Amanda , Mani Navin , Span Paul N. , Irlam Joely J. , Taylor Janet , Betts Guy N.J. , Denley Helen , Miller Crispin J. , Homer Jarrod J. , Rojas Ana M. , Hoskin Peter J. , Buffa Francesca M. , Harris Adrian L. , Kaanders Johannes H.A.M. , West Catharine M.L.
Published: April 2023

Supplementary data
Supplementary Table 2 from Genetic Profiling Identifies Two Classes of Soft-Tissue Leiomyosarcomas with Distinct Clinical Characteristics
Authors: Italiano Antoine , Lagarde Pauline , Brulard Céline , Terrier Philippe , Laë Marick , Marques Bernard , Ranchere-Vince Dominique , Michels Jean-Jacques , Trassard Martine , Cioffi Angela , Piperno-Neumann Sophie , Chevreau Christine , Blay Jean-Yves , Delcambre Corinne , Isambert Nicolas , Penel Nicolas , Bay Jacques-Olivier , Bonvalot Sylvie , Le Cesne Axel , Coindre Jean-Michel , Chibon Frédéric
Published: April 2023

PDF file - 66K, Significant Prognostic Factors for Metastasis-free Survival (MFS) and Overall survival (OS) (univariate analysis)
Supplementary Figure Legend from Genetic Profiling Identifies Two Classes of Soft-Tissue Leiomyosarcomas with Distinct Clinical Characteristics
Authors: Italiano Antoine , Lagarde Pauline , Brulard Céline , Terrier Philippe , Laë Marick , Marques Bernard , Ranchere-Vince Dominique , Michels Jean-Jacques , Trassard Martine , Cioffi Angela , Piperno-Neumann Sophie , Chevreau Christine , Blay Jean-Yves , Delcambre Corinne , Isambert Nicolas , Penel Nicolas , Bay Jacques-Olivier , Bonvalot Sylvie , Le Cesne Axel , Coindre Jean-Michel , Chibon Frédéric
Published: April 2023

PDF file - 34K
Supplementary Figure 1 from Genetic Profiling Identifies Two Classes of Soft-Tissue Leiomyosarcomas with Distinct Clinical Characteristics
Authors: Italiano Antoine , Lagarde Pauline , Brulard Céline , Terrier Philippe , Laë Marick , Marques Bernard , Ranchere-Vince Dominique , Michels Jean-Jacques , Trassard Martine , Cioffi Angela , Piperno-Neumann Sophie , Chevreau Christine , Blay Jean-Yves , Delcambre Corinne , Isambert Nicolas , Penel Nicolas , Bay Jacques-Olivier , Bonvalot Sylvie , Le Cesne Axel , Coindre Jean-Michel , Chibon Frédéric
Published: April 2023

PDF file - 23K, Kaplan-Meier curves of metastasis-free survival (A) and overall survival (B) for the overall population
Supplementary Figure 7 from Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas
Authors: Wakimoto Hiroaki , Tanaka Shota , Curry William T. , Loebel Franziska , Zhao Dan , Tateishi Kensuke , Chen Juxiang , Klofas Lindsay K. , Lelic Nina , Kim James C. , Dias-Santagata Dora , Ellisen Leif W. , Borger Darrell R. , Fendt Sarah-Maria , Vander Heiden Matthew G. , Batchelor Tracy T. , Iafrate A. John , Cahill Daniel P. , Chi Andrew S.
Published: April 2023

PDF file - 294KB, Supplementary Figure S7. PDGFRA and MET amplification sensitize IDH1-mutant glioma TICs to targeted inhibitors.
Supplementary Figure 5 from Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas
Authors: Wakimoto Hiroaki , Tanaka Shota , Curry William T. , Loebel Franziska , Zhao Dan , Tateishi Kensuke , Chen Juxiang , Klofas Lindsay K. , Lelic Nina , Kim James C. , Dias-Santagata Dora , Ellisen Leif W. , Borger Darrell R. , Fendt Sarah-Maria , Vander Heiden Matthew G. , Batchelor Tracy T. , Iafrate A. John , Cahill Daniel P. , Chi Andrew S.
Published: April 2023

PDF file - 266KB, Supplementary Figure S5. Maintenance of genotype upon serial xenotransplantation.
Supplementary Figure Legends from Mesenchymal Stem Cells from Human Fat Engineered to Secrete BMP4 Are Nononcogenic, Suppress Brain Cancer, and Prolong Survival
Authors: Li Qian , Wijesekera Olindi , Salas Sussan J. , Wang Joanna Y. , Zhu Mingxin , Aprhys Colette , Chaichana Kaisorn L. , Chesler David A. , Zhang Hao , Smith Christopher L. , Guerrero-Cazares Hugo , Levchenko Andre , Quinones-Hinojosa Alfredo
Published: April 2023

Supplementary Figure Legends
Supplemental Figure 6 from Mesenchymal Stem Cells from Human Fat Engineered to Secrete BMP4 Are Nononcogenic, Suppress Brain Cancer, and Prolong Survival
Authors: Li Qian , Wijesekera Olindi , Salas Sussan J. , Wang Joanna Y. , Zhu Mingxin , Aprhys Colette , Chaichana Kaisorn L. , Chesler David A. , Zhang Hao , Smith Christopher L. , Guerrero-Cazares Hugo , Levchenko Andre , Quinones-Hinojosa Alfredo
Published: April 2023

Supplemental SFig. 6. hAMSCs-BMP4 decrease TNF-Î± and VEGF in tumor mass in vivo.
Supplementary Figure 1 from microRNA-224 Promotes Cell Proliferation and Tumor Growth in Human Colorectal Cancer by Repressing PHLPP1 and PHLPP2
Authors: Liao Wen-Ting , Li Ting-Ting , Wang Zheng-Gen , Wang Shu-Yang , He Mei-Rong , Ye Ya-Ping , Qi Lu , Cui Yan-Mei , Wu Ping , Jiao Hong-Li , Zhang Chi , Xie Yi-Jun , Wang Jun-Xian , Ding Yan-Qing
Published: April 2023

Supplementary Figure 1 - PDF file 138K, Supplementary Fig.S1. miR-224 promotes human CRC cell growth and proliferation
Supplementary Figure S1 from Alpha-Smooth Muscle Actin (ACTA2) Is Required for Metastatic Potential of Human Lung Adenocarcinoma
Authors: Lee Hye Won , Park Young Mi , Lee Se Jeong , Cho Hyun Jung , Kim Duk-Hwan , Lee Jung-Il , Kang Myung-Soo , Seol Ho Jun , Shim Young Mog , Nam Do-Hyun , Kim Hyeon Ho , Joo Kyeung Min
Published: April 2023

Supplementary Figure S1 - PDF file 84K, Supplementary Figure S1. Verification of specific detection of ACTA2 in lung ADC primary tumors Immunohistochmical staining patterns by two different antibodies against ACTA2 purchased from Dako and Thermo Scientific Pierce were compared in primary lung tumors from ACTA2-High and Low group
Supplementary Figure 5 from BRaf and MEK Inhibitors Differentially Regulate Cell Fate and Microenvironment in Human Hepatocellular Carcinoma
Authors: Breunig Christian , Mueller Bernadett J. , Umansky Ludmila , Wahl Kristin , Hoffmann Katrin , Lehner Frank , Manns Michael P. , Bantel Heike , Falk Christine S.
Published: April 2023

Apoptosis induction, cell proliferation and viability after MAPK inhibitor treatment. (A) Apoptosis was determined in HepG2, Hep3B and Huh-7 cells after treatment with 0.2 (light gray bar), 1 (dark gray bar) or 5µM (black bar) inhibitor or DMSO (white bar) at 48h by measuring the subG1 peak using propidium iodide. (B) Cell division was determined by eFluor670 labeling of HepG2, Hep3B and Huh-7 cells after 96h treatment with the different inhibitor concentrations and detected by flow cytometry. (C) The WST-1 metabolic assay was used to detect the viability/proliferation of the three cell lines after treatment with the respective inhibitors for 72h. Each bar represents the mean {plus minus} SDs from three to six replicates.
Supplementary Table 2 from Inhibition of Protein Kinase C/Twist1 Signaling Augments Anticancer Effects of Androgen Deprivation and Enzalutamide in Prostate Cancer
Authors: Shiota Masaki , Yokomizo Akira , Takeuchi Ario , Imada Kenjiro , Kashiwagi Eiji , Song YooHyun , Inokuchi Junichi , Tatsugami Katsunori , Uchiumi Takeshi , Naito Seiji
Published: April 2023

XLSX file 9K, Ct value of genes in LNCaP and 22Rv1 cells
Supplementary Figure 3C from BRaf and MEK Inhibitors Differentially Regulate Cell Fate and Microenvironment in Human Hepatocellular Carcinoma
Authors: Breunig Christian , Mueller Bernadett J. , Umansky Ludmila , Wahl Kristin , Hoffmann Katrin , Lehner Frank , Manns Michael P. , Bantel Heike , Falk Christine S.
Published: April 2023

Alteration of total protein amount of MEK1, ERK1/2, c-Jun, Akt and ATF2 by MAPK inhibition. Total amount of MEK1, ERK1/2, c-Jun, Akt and ATF2 of HepG2 (A), Hep3B (B) and Huh-7 (C) cells after treatment with 0.2, 1 or 5µM sorafenib, PLX4720, U0126, AZD6244, PD0325901, GW5074 or sunitinib at different time points.
Supplementary Figure 4 from A Peptide-Based Positron Emission Tomography Probe for In Vivo Detection of Caspase Activity in Apoptotic Cells
Authors: Hight Matthew R. , Cheung Yiu-Yin , Nickels Michael L. , Dawson Eric S. , Zhao Ping , Saleh Samir , Buck Jason R. , Tang Dewei , Washington M. Kay , Coffey Robert J. , Manning H. Charles
Published: April 2023

PDF file - 137KB, IHC semi-quantification. Semi-quantitative analysis of cleaved caspase-3 histological samples of DLD-1 and SW620 xenograft tumors treated with vehicle or AZD-1152 (A). Evaluation of multiple low field (2.5x) micrographs revealed a statistical significant difference between vehicle- and drug-treated SW620 (p < 0.0001) tumors but not for analogously treated DLD-1 tumors (p = 0.524). Similar analysis of cleaved caspase-3 histological samples of COLO-205 and LIM-2405 treatment cohorts revealed a statistical significant difference between vehicle-treated and combination-treated COLO-205 (p = 0.025) tumors but not for analogously treated LIM-2405 tumors (p = 0.325) (B).
Supplementary Figure 3 from A Peptide-Based Positron Emission Tomography Probe for In Vivo Detection of Caspase Activity in Apoptotic Cells
Authors: Hight Matthew R. , Cheung Yiu-Yin , Nickels Michael L. , Dawson Eric S. , Zhao Ping , Saleh Samir , Buck Jason R. , Tang Dewei , Washington M. Kay , Coffey Robert J. , Manning H. Charles
Published: April 2023

PDF file - 93KB, Scheme 2. 18FSFB (9) (A) and 18FFB-VAD-FMK (11) (B) synthetic schemes. Compound (9) radiosynthesis was performed systematically using an automated radiochemistry module.
Supplementary Figure 1 from Synergistic Anticancer Effects of Pam3CSK4 and Ara-C on B-Cell Lymphoma Cells
Authors: Lee Sae-Kyung , Chwee Jyh Y. , Ma Cheryl A.P. , Le Bert Nina , Huang Caleb W. , Gasser Stephan
Published: April 2023

PDF file - 523K, Pam3CSK4 enhances Ara-C-induced upregulation of immuno-modulatory molecules on EμM2 and BC2 cells.
Supplementary Table 4 from A Signature Predicting Poor Prognosis in Gastric and Ovarian Cancer Represents a Coordinated Macrophage and Stromal Response
Authors: Busuttil Rita A. , George Joshy , Tothill Richard W. , Ioculano Kylie , Kowalczyk Adam , Mitchell Catherine , Lade Stephen , Tan Patrick , Haviv Izhak , Boussioutas Alex
Published: April 2023

XLS file - 42KB, Probes represented in cluster 27.
Supplementary Table 3 from A Signature Predicting Poor Prognosis in Gastric and Ovarian Cancer Represents a Coordinated Macrophage and Stromal Response
Authors: Busuttil Rita A. , George Joshy , Tothill Richard W. , Ioculano Kylie , Kowalczyk Adam , Mitchell Catherine , Lade Stephen , Tan Patrick , Haviv Izhak , Boussioutas Alex
Published: April 2023

XLS file - 27KB, Top 50 Differentially expressed genes.
Supplementary Figures 1 - 7 from Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma
Authors: Mydlarz Wojciech , Uemura Mamoru , Ahn Sun , Hennessey Patrick , Chang Steven , Demokan Semra , Sun Wenyue , Shao Chunbo , Bishop Justin , Krosting Julie , Mambo Elizabeth , Westra William , Ha Patrick , Sidransky David , Califano Joseph
Published: April 2023

PDF file - 133K, Supplementary Figure 1. miRNA-21 is upregulated in HNSCC tumors. Supplementary Figure 2. RT-qPCR validation of miRNA-21 overexpression by transient transfection. (A) pre-miRNA-21 and (B) miRNA-21 expression level. Supplementary Figure 3. miRNA-21 overexpression stimulates cell proliferation. All measurements were obtained with the Cell Counting Kit -8 cell proliferation assay. ∗p<0.01. Supplementary Figure 4. miRNA-21 loses specificity for CLU transcript when miRNA-21 binding seed sequence is deleted from the CLU 3'UTR sequence. ∗p<0.03. Supplementary Figure 5. Relative expression of CLU-1 in normal and HNSCC cell lines. Supplementary Figure 6. RT-qPCR validation of CLU-1 overexpression by transient transfection. Supplementary Figure 7. CLU-1 has growth inhibitory effects in JHU-O28, FaDu and SCC9 HNSCC cell lines. Overexpression of CLU-1 inhibits cell proliferation. All measurements were obtained by taking direct cell counts at each time point. ∗p<0.05.
Supplementary Figure 3 from The Integrin Inhibitor Cilengitide Affects Meningioma Cell Motility and Invasion
Authors: Wilisch-Neumann Annette , Kliese Nadine , Pachow Doreen , Schneider Thomas , Warnke Jan-Peter , Braunsdorf Werner EK , Böhmer Frank-Dietmar , Hass Peter , Pasemann Diana , Helbing Cornelia , Kirches Elmar , Mawrin Christian
Published: April 2023

Supplementary Figure 3 - PDF file 43K, Overall survival of mice treated with cilengitide and control animals
Supplementary Figure 1 from Toward Prediction of Efficacy of Chemotherapy: A Proof of Concept Study in Lung Cancer Patients Using [11C]docetaxel and Positron Emission Tomography
Authors: van der Veldt Astrid A.M. , Lubberink Mark , Mathijssen Ron H.J. , Loos Walter J. , Herder Gerarda J.M. , Greuter Henri N. , Comans Emile F.I. , Rutten Hugo B. , Eriksson Jonas , Windhorst Albert D. , Hendrikse N. Harry , Postmus Pieter E. , Smit Egbert F. , Lammertsma Adriaan A.
Published: April 2023

PDF File - 1091K, Schematic diagram illustrating the various analyses that were performed to estimate the accumulated amount of docetaxel in tumor tissue.
Supplementary Figure 4 from Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363
Authors: Lamoureux Francois , Thomas Christian , Crafter Claire , Kumano Masafumi , Zhang Fan , Davies Barry R. , Gleave Martin E. , Zoubeidi Amina
Published: April 2023

PDF file - 56 KB, AZD5363 doesn't affect RIP kinase and ROS.
Supplementary Table 3 from Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas
Authors: McCleland Mark L. , Adler Adam S. , Deming Laura , Cosino Ely , Lee Leslie , Blackwood Elizabeth M. , Solon Margaret , Tao Janet , Li Li , Shames David , Jackson Erica , Forrest William F. , Firestein Ron
Published: April 2023

XLS file - 155K, Patient characteristics for tumors used in the LDHB and survival correlation analysis
Supplementary Figure 2 from Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363
Authors: Lamoureux Francois , Thomas Christian , Crafter Claire , Kumano Masafumi , Zhang Fan , Davies Barry R. , Gleave Martin E. , Zoubeidi Amina
Published: April 2023

PDF file - 92 KB, A, AZD5363 fails to induce apoptosis in PC-3 and DU145 cells
Supplementary Figure 5 from Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas
Authors: McCleland Mark L. , Adler Adam S. , Deming Laura , Cosino Ely , Lee Leslie , Blackwood Elizabeth M. , Solon Margaret , Tao Janet , Li Li , Shames David , Jackson Erica , Forrest William F. , Firestein Ron
Published: April 2023

PDF file - 150K, LDHB expression correlates with poor overall survival in lung tumors
Supplementary Figure 3 from Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas
Authors: McCleland Mark L. , Adler Adam S. , Deming Laura , Cosino Ely , Lee Leslie , Blackwood Elizabeth M. , Solon Margaret , Tao Janet , Li Li , Shames David , Jackson Erica , Forrest William F. , Firestein Ron
Published: April 2023

PDF file - 160K, RNAi of KRAS to determine cellular dependence on proliferation and effects on LDHB expression
Figure S7 from Targeting Treatment-Resistant Breast Cancer Stem Cells with FKBPL and Its Peptide Derivative, AD-01, via the CD44 Pathway
Authors: McClements Lana , Yakkundi Anita , Papaspyropoulos Angelos , Harrison Hannah , Ablett Matthew P. , Jithesh Puthen V. , McKeen Hayley D. , Bennett Rachel , Donley Christopher , Kissenpfennig Adrien , McIntosh Stuart , McCarthy Helen O. , O'Neill Eric , Clarke Robert B. , Robson Tracy
Published: April 2023

Figure S7 - PDF file 47K, Figure S7. High FKBPL and low Oct4 expression shows a trend towards better patient survival. Samples with opposing FKBPL and Oct4 expression (high FKBPL/low Oct4 and low FKBPL/high Oct4) were analyzed using microarray data from publically available data set (GSE7390). Samples were stratified based on median expression values of Oct4 and FKBPL. Kaplan-Meier survival curves of breast cancer patients (n=104) presented