bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic and histopathological associations with outcome in pediatric pilocytic astrocytoma
Authors: Cler Samuel J. , Skidmore Alexander , Yahanda Alexander T. , Mackey Kimberly , Rubin Joshua B. , Cluster Andrew , Perkins Stephanie , Gauvain Karen , King Allison A. , Limbrick David D. , McEvoy Sean , Park Tae Sung , Smyth Matthew D. , Mian Ali Y. , Chicoine Michael R. , Dahiya Sonika , Strahle Jennifer M.
Published: February 2022

OBJECTIVE

Pilocytic astrocytomas (PAs) have a generally favorable prognosis; however, progression or recurrence after resection is possible. The prognostic value of histopathological qualifiers (defined below) or BRAF alterations is not well understood. The aim of this study was to identify the prognostic value of genetic and histopathological features of pediatric PAs.

METHODS

Patients treated for a WHO grade I PA at a single institution were analyzed for histopathological and genetic features and outcomes. “Histopathological qualifier” refers to designations such as "WHO grade I PA with increased proliferative index." BRAF alterations include gene fusions and point mutations. Patients with neurofibromatosis type 1 were excluded.

RESULTS

A total of 222 patients were analyzed (51% female, mean age 9.6 years). Tumors were located in the cerebellum/fourth ventricle (51%), optic pathway/hypothalamus (15%), brainstem (12%), and cerebral cortex (11%). BRAF alterations were screened for in 77 patients and identified in 56 (73%). Histopathological qualifiers were present in 27 patients (14%). Resection was performed in 197 patients (89%), 41 (21%) of whom displayed tumor progression or recurrence after resection. Tumor progression or recurrence was not associated with histopathologic qualifiers (p = 0.36) or BRAF alterations (p = 0.77). Ki-67 proliferative indices were not predictive of progression or recurrence (p = 0.94). BRAF alterations, specifically KIAA1549 fusions, were associated with cerebellar/fourth ventricular tumor location (p < 0.0001) and younger patient age (p = 0.03). Patients in whom gross-total resection was achieved had lower rates of progression and recurrence (p < 0.0001).

CONCLUSIONS

Histopathological features/qualifiers and BRAF alterations were not associated with tumor recurrence/progression in pediatric PAs. The extent of resection was the only factor analyzed that predicted outcome.
Subcutaneous panniculitis-like T-cell lymphoma. Clinical case
Authors:   «Vashe zdorovye» Scientific-Research Medical Center, Fatykhova E. Z. , MUKHAMADIEVA V. N. ,   Kazan State Medical University, RAKHIMOVA A. F. ,   Kazan State Medical University, YAKUPOVA S. P. ,   Kazan State Medical University, SIBGATULLIN T. B. ,   Kazan State University, BADEEVA M. Yu. ,   Republic Clinical Hospital
Published: February 2022

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare malignant tumor consisting of mature cellulotoxic α-β Т-lymphocytes, which primarily affects subcutaneous adipose tissue. Its clinical and morphological manifestations resemble panniculitis. The incidence of SPTCL is less than 1% of the non-Hodgkin lymphomas. Although the disease debuts at a median age of 35 years, it is found in all age groups. The article presents a clinical case of panniculitis-like T-cell lymphoma in a patient initially diagnosed with recurrent Weber- Christian panniculitis. However, the insufficiently effective therapy led to re-examination of the diagnosis. The timely involvement of doctors of various specialties from the federal center and the high-quality morphological diagnostics made it possible to rapidly make the correct diagnosis and start chemotherapy.
Rare forms of ectopic pregnancy (clinical observations)
Authors:   Republic Clinical Hospital, MINNULLINA F. F. , EGAMBERDIEVA L. D. ,   Kazan State Medical University, AKHMETSHINA L. R. ,   Republic Clinical Hospital
Published: February 2022

Ectopic pregnancy remains the most pressing problem in obstetrics and gynecology. Despite the improvements of the diagnosis of such forms of pregnancy, problems with the diagnosis of rare forms of extra-tubal ectopic pregnancy persist. Three cases of rare forms of ectopic pregnancy presented in the article are undoubtedly of clinical interest to obstetrician-gynecologists.
Atypical course of sinus thrombosis in combination with venous infarctions in women after the coronavirus infection
Authors:   Republic Clinical Hospital, AKHUNOVA A. G. , BOGDANOV E. I. ,   Republic Clinical Hospital, KHAIRULLOV M. A. ,   Republic Clinical Hospital
Published: February 2022

The article presents clinical cases of sinus thrombosis in women taking oral contraceptives in combination with other risk factors for increased thrombosis.Сancellation of contraceptive use should be considered as a mandatory recommendation along with other means of thromboprophylaxis in patients with the new coronavirus infection.
Features of the new coronavirus infection in a patient with a long history of systemic lupus erythematosus
Authors:   Kazan State Medical University, ISKHAKOVA E. F. , MUKHAMADIEVA V. N. ,   Kazan State Medical University, DYAKOVA E. V. ,   Republic Clinical Hospital, SHAMSUTDINOVA N. G. ,   Kazan State Medical University, ABDRAKIPOV R. Z. ,   Republic Clinical Hospital, SUKHORUKOVA E. V. ,   Republic Clinical Hospital, LAPSHINA S. A. ,   Kazan State Medical University, ABDULGANIEVA D. I. ,   Kazan State Medical University
Published: February 2022

Today the issues related to the management of patients with immunoinflammatory rheumatic diseases and the new coronavirus infection (NCI), despite numerous studies, remain open for discussion. Due to the rare occurrence of systemic lupus erythematosus (SLE), publications devoted to the study of the characteristics of the course of COVID-19 in this group of patients are limited to a description of a small series of cases. The article provides information on possible risk factors for severe NCI in patients with SLE. The article presents our own clinical observation of a patient with a long history of SLE who had bilateral pneumonia caused by SARS-CoV-2, against the background of low activity of the underlying disease, achieved by taking genetically engineered biologic drugs. NCI was accompanied by rapid progression of lung damage, prolonged persistence of fever, respiratory failure, and asthenic syndrome. Further monitoring of the patient’s condition is required.
Vitamin D in prophylactics of contamination and development of severe forms of the new coronavirus infection COVID-19
Authors:   Republic Clinical Hospital of the Republic of Tatarstan, MAKSIMOV M. L. , ZVEGINTSEVA A. A. ,   Republic Clinical Hospital of the Republic of Tatarstan, ISLAMOVA M. A. ,   Kazan State Medical Academy - Branch Campus of the FSBEI FPE RMACPE MOH Russia, KULAGINA T. YU. ,   Republic Clinical Hospital of the Republic of Tatarstan
Published: February 2022

Quarantine measures cannot comprehensively prevent further spread of SARS-CoV-2, as they do not involve the inner mechanisms of antiviral protection; thus, it is necessary to consider other prophylactic methods of contamination and development of severe forms of COVID-19. Low levels of vitamin D in blood determine a more unfavorable course of the disease and are associated with a large number of lethal outcomes of COVID-19. Also, low levels of this vitamin correlate with higher vulnerability to SARS-CoV-2. Meta analysis of 25 randomized studies showed that intake of vitamin D reliably reduces the risk of ARVI contamination by 12% on average and also reduces the risk of repeated ARVI contamination in persons having at least one ARVI episode in a year. It is essential to use the available methods of CO VID-19 prophylactics, one of which is adequate provision with vitamin D.
Gender differences and clinical features of liver and biliary tract diseases
Authors:   Kazan State Medical University of the Ministry of Health of Russia, BODRYAGINA E. S. , AKBEROVA D. R. ,   Kazan State Medical University, MUKHAMETOVA D. D. ,   Kazan State Medical University, ABDULGANIEVA D. I. ,   Kazan State Medical University, ODINTSOVA A. KH. ,   Republic Clinical Hospital
Published: February 2022

The purpose — to reveal the clinical and socio-demographic characteristics of patients with liver and biliary tract diseases depending on nosology; to determine gender differences of the patients. Material and methods. 292 patients with liver and biliary tract diseases were examined. The patients were on inpatient treatment in the Gastroenterology Department of the Republic Clinical Hospital or observed in the outpatient department. Results. Among 292 patients, 123 (42,1%) had steatosis, 11 (3,8%) — cholelithiasis, 6 (2,1%) — Gilbert’s syndrome, 152 (52,0%) — autoimmune liver disease (AILD). The prevalence of females was revealed among patients with both hepatic steatosis (67,9%) and AILD (91%). Male patients with non-alcoholic fatty liver disease (NAFLD) had an earlier age of disease onset compared to female patients (47,1 (2,6) vs 53,8 (1,6)). Associated conditions in patients with NAFLD included obesity, cholelithiasis, acid-related diseases, dyslipidemia, impaired motility of the digestive tract, etc.; in patients with AILD — arthralgia, autoimmune thyroiditis, inflammatory bowel disease and other autoinflammatory conditions. The main focus in the management of NAFLD patients was made on non-drug therapy methods, including changes in eating behavior and prevention of hypodynamia, while in patients with AILD drug therapy (immunosuppressants, corticosteroids) played the main role. Patients with NAFLD had a more favorable course of the disease, which made it possible to observe them in the outpatient department, while patients with AILD mostly got inpatient treatment.
Cognitive impairments in patients after COVID-19
Authors:   Republic Clinical Hospital, DYAKOVA E. V. , SPIRIDONOVA N. S. ,   Republic Clinical Hospital, MINGAZOVA L. I. ,   Republic Clinical Hospital, NIZAMOVA S. R. ,   Republic Clinical Hospital, SHAMSUTDINOVA N. G. ,   Kazan State Medical University, KIRILLOVA E. R. ,   Kazan State Medical University, GAYSINA D. M. ,   Kazan State Medical University, FATYKHOVA A. M. ,   Kazan State Medical University, ABDULGANIEVA D. I. ,   Kazan State Medical University
Published: February 2022

The purpose — to assess the severity of cognitive deficit in patients with previous COVID-19. Material and methods. We examined 20 patients after COVID-19 hospitalized in the Pulmonology Department of Republic Clinical Hospital of the Republic of Tatarstan. All patients underwent general clinical and laboratory examination, computed tomography of the lungs, and tests with a 6-minute walk. To assess the severity of dyspnea, we used the MMRS questionnaire and the Borg scale. We used the Montreal Cognitive Assessment Scale (MoCA), the Mini-Cog test, and the MMSE to identify cognitive functions. Results. After analyzing the data of patients with mild severity (CT 1), we found that cognitive functions and the volume of lung lesions did not have a significant relationship. In patients with large lung lesions (CT 2–4), there was a correlation between the detection rate and the percentage of frosted glass detection on the one hand and the results of the MiniCog test, on the other (r = -0,69 and r = -0,93). Also, in this group of patients, we found a strong positive correlation (r = -0,8) between the frosted glass ratio and the Borg score at rest. It shows that patients with smaller changes in the lungs assess the dyspnea severity more correctly. Conclusion. Patients after COVID-19 have cognitive impairments of varying severity. In the group of patients with more severe lung damage (CT 2–4), there are changes in cognitive functions that correlate with the functional status of the patient.
Der Brückenbauer. Intervista con Dario Siddi
Authors: Usadel Marie , Corgiolu Francesco
Published: February 2022

Dario Siddi was a teacher and a student, theater director and actor, an archaeologist. Born in 1944 he lived and worked as a middle school teacher in Sant’Antioco and Calasetta in Sardinia. In 1988 he founded Il Calderone, a small theater company: however, over time the association would also become active in other areas of social and cultural life in Sant’Antioco, from the integration of immigrants to the organization of cinematic events. After his passing in 2020 his friends called him a bridge-builder, which is probably the best description of the role he played in the archaeological life of Sant’Antioco.

Together with his fellow members of Il Calderone he initiated a cooperation with researchers of the Ruhr-University Bochum (Germany). The resulting archaeological project, under the direction of Constance von Rüden, is aimed at investigating the prehistoric settlement system of the Canai-plain in the southern part of Sant’Antioco with a particular interest in the Nuragic period. Since 2017 there have been annual field campaigns comprising a systematic survey in the plain, targeted prospection of the surrounding Nuragic sites as well as the detailed documentation of the area called Gruttiacqua in the south-western part of the Canai-plain. In 2019 it was possible to begin excavating part of the Nuragic village of Gruttiacqua. Since this project represents one of the rare cases where the archaeologists were chosen by the community and not the other way around, the cooperation between students, international researchers and members of Il Calderone is an essential, original element that directly and more effectively involves the local community.
Disegnare per Osservare, Capire, Raccontare. Conversazione con Agostino Sotgia
Authors: Revello Lami Martina
Published: February 2022

Agostino Sotgia (Roma, 1990) è dottorando in archeologia preistorica presso la “Sapienza – Università di Roma” e la “RUG – University of Groningen”. Si occupa prevalentemente di Landscape Archaeology con particolare attenzione alla ricostruzione dei paesaggi agro-pastorali antichi in Etruria Meridionale a cavallo del I millennio a.C. Precedentemente si è interessato alla cultura materiale con una serie di studi sulle fornaci e le aree produttive per il vasellame ceramico in Italia peninsulare tra Età del bronzo e Età arcaica. All’attività di ricerca ha affiancato anche quella di sorveglianza archeologica nei cantieri per la creazione dell’infrastrutture della fibra ottica e del Gas. Collabora, inoltre, come disegnatore di reperti archeologici presso numerosi gruppi di ricerca e singoli ricercatori.
The Confederazione Italiana Archeologi social media projects during the Covid-19 pandemic in Italy: changing the digital communication approach to the online community.
Authors: Donati Nicolò , Gusberti Elisa , Magliaro Tommaso , Riva Alessandra
Published: February 2022

With the onset of the Covid-19 pandemic, social media has rapidly become a crucial communication tool for sharing information with the public. In this article, we shall examine two media projects: #CIAndremo and Una domenica al museo launched on the social media pages of the CIA - Confederazione Italiana Archeologi following the lockdown stages in Italy in 2020. #CIAndremo is the first original project that our association released on Facebook, Instagram IGTV and YouTube during the pandemic, responding to the social campaign #iorestoacasa (I stay at home) as a measure to contain the epidemic outbreak. We will present the methods and procedures used to produce the videos, the limitations we faced because of the lockdown and the final positive feedback received from the public. The second project was the enhancement of Una Domenica al Museo (Sunday at the Museum), a weekly column born on the CIA Instagram profile, which is advertised with the hashtag #unadomenicaalmuseo. Here we are presenting the adaptation of the format that followed the Italian government lockdown restrictions and how it also changed the interaction with the public.
Estimating the minimal clinically important difference for balance and gait outcome measures in individuals with vestibular disorders
Authors: Wellons Rachel D. , Duhe Sydney E. , MacDowell Sara G. , Hodge April , Oxborough Sara , Levitzky Elizabeth E.
Published: February 2022

BACKGROUND: Vestibular Rehabilitation Therapists (VRT) utilize outcome measures to quantify gait and balance abilities in individuals with vestibular disorders (IVD). The minimal clinically important difference (MCID) in gait and balance outcome measures for IVD is unknown. OBJECTIVE: The purpose of this study is to estimate the MCID of the Activities-specific Balance Confidence Scale (ABC), Functional Gait Assessment (FGA), and Gait Speed (GS) using distribution and anchor-based methods relative to the Dizziness Handicap Inventory (DHI) in IVD. METHODS: Data were collected using a retrospective chart review from two outpatient Vestibular Rehabilitation (VR) clinics. Data included demographic characteristics, diagnosis, VR course, and pre and post outcome measures including DHI, ABC, FGA, and GS. The DHI was used to classify subjects as “responders” or “non-responders” in order to calculate MCID values. RESULTS: The total number of subjects analyzed for each outcome measure was 222 for the ABC, 220 for FGA, and 237 for GS. Subjects made statistically significant improvements in ABC, DHI, FGA, and GS (p < 0.001) from pre to post VR. The MCID calculated for ABC, FGA, and GS using the anchor-based approach was 18.1%, 4 points, and 0.09 m/s respectively. The MCIDs calculated using distribution-based approach for the ABC ranged between 7.5–23.5%, FGA ranged between 1.31–4.15 points, and GS ranged between 0.07 m/s–0.22 m/s. CONCLUSIONS: The anchor-based calculations of the MCID of 18.1%, 4 points, and 0.09 m/s for ABC, FGA, and GS respectively for IVD should be used over distribution-based calculations. This is due to strength of DHI as the anchor and statistical analysis. VRT and researches can use these values to indicate meaningful changes in gait and balance function in IVD.
Vestibulo-ocular reflex gain improvements at peak head acceleration and velocity following onset of unilateral vestibular neuritis: Insights into neural compensation mechanisms
Authors: Cleworth Taylor W. , Kessler Paul , Honegger Flurin , Carpenter Mark G. , Allum John H.J.
Published: February 2022

BACKGROUND AND AIMS: An acute unilateral peripheral vestibular deficit (aUPVD) due to vestibular neuritis causes deficient yaw axis vestibular ocular reflex (VOR) gains. Using video head impulse tests (vHITs), we examined phasic and tonic velocity gains of the VOR over time to determine if these differed at onset and during subsequent improvement. METHODS: The VOR responses of 61 patients were examined within 5 days of aUPVD onset, and 3 and 7 weeks later using vHIT with mean peak yaw angular velocities of 177°/s (sd 45°/s) and mean peak accelerations of 3660°/s2 (sd 1300°/s2). The phasic velocity or acceleration gain (aG) was computed as the ratio of eye to head velocity around peak head acceleration, and the tonic velocity gain (vG) was calculated as the same ratio around peak head velocity. RESULTS: aG increased ipsi-deficit from 0.45 at onset to 0.67 at 3 weeks and 7 weeks later, and vG increased ipsi-deficit from 0.29 to 0.51 and 0.53, respectively, yielding a significant time effect (p < 0.001). Deficit side aG was significantly greater (p < 0.001) than vG at all time points. Deficit side gain improvements in aG and vG were similar. Contra-deficit aG increased from 0.86 to 0.95 and 0.94 at 3 weeks and 7 weeks, and vG contra-deficit increased from 0.84, to 0.89 and 0.87, respectively, also yielding a significant time effect (p = 0.004). Contra-deficit aG and vG were normal at 3 weeks. Mean canal paresis values improved from 91% to 67% over the 7 weeks. CONCLUSIONS: Acceleration and velocity VOR gains on the deficit side are reduced by aUPVD and improve most in the first 3 weeks after aUPVD onset. Deficit side aG is consistently higher than deficit side vG following an aUPVD, suggesting that acceleration rather than velocity sensitive compensatory neural mechanisms are predominant during the compensation process for aUPVD.
Investigations on coronary artery plaque detection and subclassification using machine learning classifier
Authors: Indumathy D. , Ramesh K. , Senthilkumar G. , Sudha S.
Published: February 2022

Coronary artery diseases are one of the high-risk diseases, which occur due to the insufficient blood supply to the heart. The different types of plaques formed inside the artery leads to the blockage of the blood stream. Understanding the type of plaques along with the detection and classification of plaques supports in reducing the mortality of patients. The objective of this study is to present a novel clustering method of plaque segmentation followed by wavelet transform based feature extraction. The extracted features of all different kinds of calcified and sub calcified plaques are applied to first train and test three machine learning classifiers including support vector machine, random forest and decision tree classifiers. The bootstrap ensemble classifier then decides the best classification result through a voting method of three classifiers. A training dataset including 64 normal CTA images and 73 abnormal CTA images is used, while a testing dataset consists of 111 normal CTA images and 103 abnormal CTA images. The evaluation metrics shows better classification rate and accuracy of 97.7%. The Sensitivity and Specificity rates are 97.8% and 97.5%, respectively. As a result, our study results demonstrate the feasibility and advantages of developing and applying this new image processing and machine learning scheme to assist coronary artery plaque detection and classification.
HUBUNGAN DUKUNGAN KELUARGA TERHADAP PRAKTEK PEMBERIAN ASI DI WILAYAH PUSKESMAS SUDIANG RAYA KOTA MAKASSAR
Authors: Fanny Lydia , Lestari Retno Sri , Chaerunnimah Chaerunnimah
Published: February 2022

Backgrounds: Exclusive breastfeeding is beneficial to reduce child mortality and improve maternal health that compatible with the one of Sustainable Development Goals (SDGs) that ensuring the child get exclusive breastfeeding during the first six months of the birth.Objectives: This research aims to determine the relationship of family support to the practice of giving breastmilk to the baby in PuskesmasSudiang Raya Makassar area.Methods: This research is an analytic survey with Cross Sectional design. The population was 126 breastfeeding mothers. The statistical analysis used is the Coefficient of Contingency with α = 0,05.Results: The result showed that mothers who give breastmilk to their babies have a good family support of 57,6% and there is a relationship between family support and the practice of giving breastmilk to the baby in PuskesmasSudiang Raya Makassar area.Conclusions: Good family support can increase the amount of mothers who give breastmilk to their baby.Keywords: Breastmilk, Family Support, Baby, Mother
HUBUNGAN ASUPAN ZAT GIZI PROTEIN DENGAN STATUS GIZI BALITA USIA 6-24 BULAN DI RW 2 WILAYAH PUSKESMAS BATUA KOTA MAKASSAR
Authors: Lala Manji , Inrivianthy Donna , Suaib Fatmawaty
Published: February 2022

Backgrounds:Nutrition problem is a health problem that influenced by many factors. Malnuorished toddlers has slow growth and development than the healthy toddler, if the problem has not solve it can caused health problem until the toddler become mature. Aged of 0-24 months is a golden period of growth and development.Objectives:This research aims to determine the relationship of protein intake with toddler’s nutritional status aged 6-24 months in RW 2 Puskesmas Batua Area Makassar City.Methods:This research is an descriptive-analytic with cross sectional study design. The population were all the toddler aged 6-24 months in RW 2 Puskesmas Batua. Sample was selected by random sampling method. Total sample were 35 toddler. The statistical analysis test that used was chi square with the degree of significancy 0,05.Results:The results showed that protein intake 17 toddler  was good (48,6%) compared to the others (51,4%). Based on data analysis found that there were not significant relationship between protein intake with toddler’s nutritional status aged 6-24 months based on bb/u index with p:0,125, tb/u index with p: 0,380 and bb/tb index with p: 0,323.Conclusions:There were not significant relationship between protein intake with toddler’s nutritional status aged 6-24 months in RW 2 Puskesmas Batua area Makassar cityKeywords: Protein,  Nutritional status and ToddlerHUBUNGAN ASUPAN ZAT GIZI PROTEIN DENGAN STATUS GIZI BALITA USIA 6-24 BULAN DI RW 2 WILAYAH PUSKESMAS BATUA KOTA MAKASSAR
SENAM AEROBIK INTENSITAS SEDANG DAN PENURUNAN BERAT BADAN, PERSEN LEMAK SERTA RASIO LINGKAR PINGGANG PANGGUL MAHASISWA GIZI YANG OVERWEIGHT
Authors: Khusnul Khatimah Khusnul Khatimah Khusnul Khatimah , Mas'ud Hikmawaty , Rauf Suriani
Published: February 2022

Background: Physical training is one of many method for solving overweight, overgrease and to reach the best freshness of body and fungtional capality from someone.Objectives: Knowing the influence of aerobicnastic (SKJ 2012) in middle intentcity for weight lost, grace percent, and hip waist rim for overweight nutrient student in Health Politeknik of Makassar.Methods: This method is research experiment with one group, pre-test and post-test design. The research will be held in nutrient faculty health polyteknik of Makassar. Sample 30 students of nutrient faculty with overweight status have been choosen by purposive sampling.Results: The result showed that the average of weight loss and grace fat amount was 1,42 kg and 1,96 mm, at the same time, the hip waist rim were not decrease. Based on data analysis found that there were a significant relationship between aerobic with middle intencity and weight loss and grace fat (p=0,000), at the same time,there were not significant relationship between aerobic with middle intentcity and hip waist rim (p=0,882).Conclusions: Energi demand is due to the physical activity. Energy source are drived from the fat-burning in the body. Regular aerobic exercise can reduce the fat strored in body so that weight loss occurs.Keyword : Aerobicnastic, Weight, Grase Persent, Hip Waist Rim
ANALISIS KANDUNGAN ZAT GIZI BROWNIES TEMPE SUBTITUSI WORTEL (Daucus carota L.) SEBAGAI ALTERNATIF PERBAIKAN GIZI TERHADAP MASYARAKAT
Authors: A. Ibrahim Irviani , Ibrahim Hasbi , Isma Rabiatul
Published: February 2022

Backgrounds: Brownies are popular food and favored by many people at different ages, including school-age children. In this study, the raw materials used in the brownies are tempe and carrot (Daucus carota L), both materials have a high content of nutrients including iron and vitamin A.Objectives: The study aims to determine the nutrients contents (carbohydrates, protein, fat, vitamin A and fe) and the organoleptic testing of the products of tempe brownies of carrot (Daucus carota L.) subtitution.Methods: The study is a true-experimental research using a completed randomized design (CRD). The results revealed that 4 treatments with different concentrations by adding carrot (Daucus carota L.) are 1:0  (100g tempe), 3:1 (75g tempe, 25g carrot), 1:1 (50g tempe, 50g carrot) and 1:3 (25g tempe, 75g carrot) with three rehashes.Results: The results of Carbohydrates research of 13.78%, protein 11.52%, fat 24.29%, vitamin A 5,17ug/g, iron 36,89ug/g. The organoleptic testing that most preferred and good quality is 1:1 treatment. The Friedman testing of P<0.05 is on scent, taste and the overall quality.Conclusions: The 1:1 ratio is the best product recommendation based on the nutrients and organoleptic testing of four samples.                                        Keywords: Brownies, Tempe, Carrot (Daucus Carota L.), Nutrient
GAMBARAN KONSUMSI GARAM BERDASARKAN PEDOMAN GIZI SEIMBANG PADA IBU RUMAH TANGGA
Authors: Rauf Suriani , Adwiah Rabiatul , Adwiah Rabiatul
Published: February 2022

Background: Excessive salt intake could increase the risk of high blood pressure or hypertension. The recommended dose limits Balanced Nutrition Guidelines (PGS) in 2014 ie 5 g / person / day equivalent to 1 tea spoon.Aims: This study aimed to describe the consumption of salt based on a balanced nutrition guidelines Housewife in Kassi Kebo District of Maros Baru.Method: This research was a descriptive cross sectional study. Samples were housewives who were in the neighborhood Kassi Kebo Village, Baju Bodoa District of Maros Baru numbering 97 people selected by purposive sampling. Salt consumption was obtained by the method of 2 x 24 hour recall questionnaire.Result: The results showed that salt consumption in housewives were generally classified as either 78.6% and the average amount of salt consumed 4.1 grams / day less than the standard PGS was 5 salt / daySuggestion: It was recommended that those housewives in Kassi kebo to keep the amount of salt consumed.Key words : Salt Consumption, PGS 2014
DAYA TERIMA PEMBUATAN MI BASAH DENGAN PENAMBAHAN TEPUNG DAUN KELOR
Authors: Salim Nur , Zakaria Zakaria , Wulandari Desi
Published: February 2022

Background: Mie is one of the staple food that consumed by many people, the problem is minerals and vitamins in the mie is very limited. Therefore it need an effort to add more vitamins and minerals in the mie, one of the ways is adding Moringa leaf powder to the mie. Moringa leaves is a plant that contains nutrients that nearly meet the human nutritional needs and useful as a nutritional improvement.Objectives: This research aims to know acceptability manufacture of wet noodle with adding Moringa leaf powder.Methods: This research is eksperimen research with the study design post test control design.Results: This research’s result is show that acceptability of wet noodle with adding Moringa leaf powder that most preferred is formula with concentration 2% and color aspect as much as 52%, taste aspect as much as 56%, aroma aspect as much as 36%, and texture aspect as much as 52%. Statistical results of anova test showed that there is the effect of adding Moringa leaf powder so followed by Tukey test stating that the panelists gave significantly different assessments (p < 0,05) of the wet noodles with the addition of moringa leaf powder. Comparison of the best material that is preferred by the panelists wet noodles with the addition of Moringa leaf powder is formula concentration of 2% with every additional 20 grams of Moringa leaf powder. Wet noodle received power with the addition of Moringa leaf powder is the most preferred concentration of 2%.Suggestion: It is suggested for further research conduct laboratory testing of nutrient content in the wet noodles with the addition of moringa leaf powder and formula concentration of 2%.Keywords : Acceptability,Wet Noodle, Moringa leaves
Oak Wilt: A Potential Future Threat to Oaks in Florida
Authors: Peacock Kelly , Smith Jason
Published: February 2022

FOR274, a 5-page fact sheet by Kelly Peacock and Jason Smith, provides information on the diagnosis, biology, and management of the disease and should provide guidance for future efforts to identify and manage oak wilt in the state of Florida. Includes references. Published by the UF Department of School of Forest Resources and Conservation, November 2010. Reviewed November 2013.
Decline of Florida Torreya: An Endemic Conifer on the Edge of Extinction
Authors: Smith Jason A. , Trulock Aaron
Published: February 2022

FOR276, a 5-page fact sheet by Jason A. Smith and Aaron Trulock, suggests a new understanding of the cause of decline and discusses current efforts to assess the population and develop a recovery plan. Includes references. Published by the UF Department of School of Forest Resources and Conservation, November 2010.
A biztonságtudatosság fogalma, fejlődése nemzetbiztonsági, terrorelhárítási és magánbiztonsági szempontból
Authors: Regényi Kund Miklós , Jasenszky Nándor , Lippai Zsolt
Published: February 2022

Cikkükben a szerzők összehasonlító megközelítést  alkalmazva mutatják be a biztonságtudatosság aktuális  kérdéskörét. A biztonság fogalmából indulnak ki, majd  áttérnek a biztonságtudatosság fogalmára, és a  nemzetbiztonsági szolgálatok vonatkozásában vázolják  fejlődésének jelentős mozzanatait. Ezt követően röviden  felvillantják a rendőri bűnmegelőzést, majd áttérnek a  biztonságtudatosítás terrorelhárítási szempontú ismertetésére. A cikk a téma magánbiztonsági szempontú  bemutatásával és egy nemzetközi környezetből vett  esettanulmánnyal fejeződik be. Az összegzésben a szerzők hitet tesznek amellett, hogy a hasonló módszertanon túl, a  nemzetbiztonsági, terrorelhárítási és magánbiztonsági  biztonságtudatosság egymást támogatja és kiegészíti.
Biztonságtudatosság – hazai helyzetkép, hazai gyakorlat és példák 2.
Authors: Mezei József , Koncz Veronika , Jasenszky Nándor
Published: February 2022

A 21. század elején számos olyan esemény és változás  történt a világban, amelyek jelentős hatást gyakoroltak a  titkosszolgálatok tevékenységére is. Ezek közül  kiemelkednek a nyugati társadalmakat sokkoló  terrorcselekmények az Amerikai Egyesült Államokban és  Európában, az információtechnológia rohamos fejlődése,  valamint ezzel együtt az ezzel kölcsönhatásban álló  információrobbanás. Ezen tényezők egyik következménye  lett a biztonságtudatosító programok rendszerszintű  megjelenése a nemzetbiztonság területén például a  terrorelhárítással és az információvédelemmel összefüggésben. E két részből álló publikáció célja, hogy  bemutassa a magyar titkosszolgálatok, illetve a  Terrorelhárítási Központ által aktuálisan folytatott, ilyen típusú programokat. A publikációt a Nemzeti Közszolgálati  Egyetem Nemzetbiztonsági Intézete által folytatott ez  irányú kutatás részeként állítottuk össze azzal a céllal, hogy a kutatásban kiindulási alapot biztosítson a nemzetközi  példákat is figyelembe vevő, a hazai programok  eredményességét elősegíteni kívánó módszertani ajánlásokhoz.
Resiliência e Mecanismos de Defesa em Pacientes com Câncer em Quimioterapia Ambulatorial
Authors: Santos Júlia Mariá Azambuja , Lorenzzoni Ana Maria Vieira , Tigre Aline , Heldt Elizeth
Published: February 2022

Introdução: A capacidade de enfrentamento de situações adversas, que e definida como resiliência, auxilia o paciente a superar as dificuldades do tratamento. Entretanto, ainda são poucos os estudos que avaliam a resiliência em pacientes com câncer que realizam quimioterapia ambulatorial. Objetivo: Avaliar a resiliência de pacientes com câncer em tratamento quimioterápico ambulatorial e verificar a correlação com os mecanismos de defesa, sintomas depressivos e de ansiedade. Método: Estudo observacional, de correlação e prospectivo, com pacientes com diagnostico de câncer, de ambos os sexos, maiores de 18 anos, alfabetizados e em início de tratamento com quimioterapia ambulatorial. Os seguintes instrumentos foram aplicados no primeiro dia de tratamento quimioterápico e após 30 a 45 dias: Escala de Resiliência, Defense Style Questionnaire (DSQ-40), Inventario de Depressão de Beck e Inventario de Ansiedade de Beck. Resultados: Um total de 55 participantes foi incluído, sendo 32 (58%) do sexo feminino, com média e desvio-padrão (DP) de idade de 54,1 (DP=12,2) anos. Os diagnósticos mais frequentes foram câncer colorretal, 15 (27%) e câncer de mama, 12 (22%). Observou-se correlação negativa significativa entre sintomas depressivos e de ansiedade com os níveis de resiliência tanto na primeira (p<0,001) como na segunda avaliação (p<0,05). Os mecanismos de defesa maduros (humor e racionalização) apresentaram correlação positiva significativa e os imaturos (atuação e cisão) demonstraram correlação negativa. Conclusão: Os resultados confirmaram que a maior capacidade de resiliência se correlaciona com o uso de mecanismos de defesa adaptativos e com menores níveis de sintomas depressivos e de ansiedade em pacientes durante a quimioterapia ambulatorial.
PENERAPAN EARLY WARNING SYSTEM (EWS) SEBAGAI DETEKSI DINI KEMATIAN DI CRITICAL CARE AREA
Authors: Pujiastuti Diah , Purwaty Enjelia , Janah Janah , Yohanes Ngadhi Pablo , Surianto Paskalis , Chrisna Dewi Rani , Talu Yunince
Published: February 2022

Keperawatan merupakan bagian terpenting dari rumah sakit dalam memberikan asuhan keperawatan yang berkesinambungan. Perawat dan tim medis lainnya dituntut untuk memberikan pelayanan yang cepat dan tepat karena waktu adalah nyawa (Time saving is life saving) dalam pelayanan keperawatan kritis. Perawat sebagai pelaksana dalam memberikan asuhan keperawatan harus melakukan pengkajian secara terfokus dan mengobservasi tanda vital agar dapat menilai dan mengetahui resiko terjadinya perburukan pasien, mendeteksi dan merespon dengan mengaktifkan emergency call. Sistem scoring pendeteksian dini atau peringatan dini untuk mendeteksi adanya perburukan keadaan pasien dengan penerapan Early Warning Scores (EWS). Tujuan memberikan informasi tentang penerapan Early Warning Scores (EWS) sebagai deteksi dini kematian di critical care area. Penelitian ini merupakan literature review lima jurnal dari web www.googlescholar.com, www.pubmed.gov, www.sciencedirect.com yang dipublikasikan dari tahun 2015 sampai dengan 2020. EWS merupakan sistem penilaian fisiologis berdasarkan penilaian cepat dan kuantitatif dari perubahan tanda-tanda vital dan pada awalnya dikembangkan untuk mengidentifikasi dan melacak pasien rawat inap yang berisiko mengalami kerusakan di luar area perawatan kritis untuk memastikan stabilisasi dini dan dipindahkan ke unit perawatan intensif (ICU) jika sesuai, dan untuk mencegah serangan jantung yang dapat dihindari. EWS efektif digunakan di IGD sebagai alat bantu monitoring kondisi pasien selain triase dan dapat memprediksi kemunduran kondisi pasien serta sangat efektif di IGD. EWS memiliki nilai prediktif yang sangat baik dan telah disepakati mempengaruhi pasien dalam kondisi yang kritis. Penerapan EWS dapat mengurangi beban kerja perawat, menurunkan angka mortalitas dan membuat manfaat bagi organisasi rumah sakit.
Prospective observational study to assess the Somatic Growth in Very Low Birth Weight infants
Authors: Janjua Dalwinder , Singh Japna , Agrawal Amit , Jadhav Devendrasing Vijaysing
Published: February 2022

Background: The birth weight is the first weight measured; an infant with low birth weight is more likely to have poor somatic growth during childhood and develop markers of metabolic risk factors at his/her later age. Objectives: To evaluate the somatic growth of very low birth weight (VLBW) infants at discharge and 40 weeks postmenstrual age and to compare the growth of small for gestational age (SGA) and appropriate for gestational age (AGA) babies. Methods: This prospective observational study was conducted over a period of one year at the neonatal unit and high-risk follow-up clinic of a tertiary care hospital. VLBW babies (weight less than 1500 g), admitted within 72 hours of life and discharged alive, were followed up prospectively. The baseline data were collected before discharge from the hospital and babies were followed up till the 40 weeks post-menstrual age. Results: Out of 53 babies enrolled, one baby had a congenital malformation, six died during NICU stay, and four were not followed up. Finally, 42 babies were followed for 40 weeks. The mean gestational age was 30 ± 2.5 weeks and mean birth weight was 1199 ± 216 gm. The mean Z scores for weight, length and head circumference at birth were -0.88, -0.59, and -0.64, respectively. These changed to -1.12, -1.12, and -1.11, respectively at the time of discharge and -1.69, -1.03, and -0.73, respectively at post-menstrual age of 40 weeks. Both SGA and AGA infants exhibited a growth lag during hospital stay as indicated by a fall in Z scores for all three parameters from birth to discharge. Exclusive enteral feeding is feasible for VLBW infants without any difference in growth compared to babies given short term parenteral nutrition. Despite aggressive enteral feeding, only one baby had NEC and none of the babies developed late onset sepsis. Conclusions: In our study, both SGA and AGA infants exhibited a growth lag during hospital stay as indicated by a fall in Z scores for all three parameters from birth to discharge. Exclusive enteral feeding is feasible for VLBW infants without any difference in growth compared to babies given short-term parenteral nutrition. Also, rapid progression of feeds did not have any significant adverse effects in our study population.
Platelet count and its indices-effectiveness in early diagnosis of neonatal sepsis
Authors: Singh Priti , Chandar Vipin
Published: February 2022

Context: Neonatal sepsis is the major cause of morbidity and mortality in developing countries requiring early diagnosis and treatment. The Gold standard Blood culture results are often delayed for 48 h with high false-negative values. Emerging evidence suggests that platelet indices such as plateletcrit, mean platelet volume (MPV), and platelet distribution width (PDW) are reliable biomarkers that are readily available while obtaining routine complete blood counts. Aim: The aim of the study was to evaluate the efficacy of platelet count (Platelets) and its indices in the early diagnosis of sepsis. Settings and Design: Blood samples were collected from all neonates admitted to the hospital with features of suspected sepsis. Materials and Methods: One hundred patients were recruited for this cross-sectional analytical prospective study. All neonates delivered in Himalayan Institute of Medical Sciences and those referred from outside with features of suspected septicemia meeting the inclusion criteria were taken for study purposes. Blood samples were collected at the time of admission. Patients were divided into three groups clinically suspected sepsis (probable sepsis), culture-positive sepsis, and culture-negative sepsis. Non-parametric tests like the Chi-square test were applied to see the association between the variables. The three groups were compared for Platelets and its indices with the Analysis of variance test. Results: MPV was 219.2, 174.8, and 205.7 (p<0.031), PDW 8.3, 12.5, and 11.5 (p<0.174) and MPV as 10.9, 9.94 and 11.9 (p<0.556) in probable sepsis, culture-positive and culture-negative sepsis, respectively. Conclusions: Platelets and its indices can be considered as a diagnostic tool for neonatal sepsis as it is cheap, rapid, and easily available and does not require additional equipment.
Black Mirror, Enhancement and the Impossibility of Forgetting
Authors: Đurković Miša
Published: February 2022

Modern cognitive and experimental science is increasingly working to explore the meaning and importance of forgetting. Forgetting is one of the most important mental functions on an individual level, but also on a
social and national level, since it enables healing, purifies the mind of difficult memories, prevents obsession with problems, and eliminates the possibility of psychosomatic illnesses. The famous British TV series Black Mirror, which has become a symbol of the challenges that modern and futuristic technology brings to man, deals with the problems that arise due to the obsession of the gadget culture with abolishing forgetting through technological enhancement. Several episodes are based on gadgets that expand the potential of memory and make it constantly available to other subjects, in the way that data from a person’s entire history become available. In a dialogue
with Brooker’s ideas, the author re–examines the problems spawned by this future society without forgetting, and searches for possible solutions.
A Prolegomenon on the Philosophical Foundations of Deep Learning as Theory of (Artificial) Intelligence
Authors: Skansi Sandro , Kardum Marko
Published: February 2022

This paper examines the philosophical foundations of deep learning. By pointing to the beginnings of deep learning and artificial neuron as a logical model of a human neuron, it is possible to claim that artificial
intelligence was developed even before its official creation and that it was strongly connected to propositional logic. Bearing in mind some major setbacks in the development of neural networks, we show that deep learning can be treated as the theory of artificial intelligence and that it falls under artificial intelligence paradigm by claiming that everything can be done with learning alone and that all intelligent behavior is learnable. Thus, deep learning is a philosophical or an epistemological approach in which a form of radical empiricism must be advocated. Therefore, there is nothing in the mind that was not in the senses, and there cannot be anything in the mind that is not learnable.
A terapia nutricional nos cuidados paliativos
Authors: Cardoso Camila Castro
Published: February 2022

Os pacientes em cuidados paliativos apresentam um estado de desnutrição agudo devido ao hipercatabolismo ocasionado pela situação de enfermidade em que se encontram. Neste contexto, o presente artigo disserta sobre o uso da terapia nutricional em pacientes no fim da vida, tendo como questão norteadora: o tratamento nutricional pode ser considerado válido e benéfico para a qualidade de vida dos pacientes em cuidados paliativos mesmo que para isso sejam utilizados métodos invasivos e incômodos ao paciente? Portanto, tem como objetivo responder a esta questão referente à aplicação da terapia nutricional em pacientes paliativos. Trata-se de uma revisão narrativa, utilizando as bases de dados Lilacs e Scielo. Como resultado, constatou-se que a terapia nutricional, em alguns casos, parece contribuir para a diminuição da desnutrição, podendo desencadear, até mesmo, algumas outras melhorias no quadro evolutivo do paciente, como o aumento do sistema imunológico. No entanto, para uma parcela de profissionais da saúde, esses benefícios são questionáveis diante das consequências e complicações que esse suporte nutricional pode causar aos pacientes críticos. Devido à escassez de evidências científicas para a decisão da administração da terapia nutricional e pela alimentação ter um forte significado cultural, concluiu-se que esta decisão deverá ser multiprofissional e ter a aceitação da família por escrito, caso o paciente esteja impossibilitado de decidir. Caso o paciente opte por não receber o apoio nutricional, sua decisão deverá ser respeitada e atendida pela equipe e por seus familiares, valorizando sua autonomia.
Uso da telefonoaudiologia para pacientes em atendimento domiciliar durante a pandemia de Covid-19
Authors: Santos Patrícia Rocha dos , Souza Luiz Augusto de Paula , Mendes Vera Lucia Ferreira , Costa Rogério da , Cunha Maria Claudia , Palladino Ruth Ramalho Ruivo
Published: February 2022

Tudo indica que o teleatendimento é uma modalidade de assistência em rápido processo de consolidação, mas de que modo, com quais potencialidades e limites? Este artigo traz reflexões sobre essa atuação durante a pandemia da COVID-19 no contexto de profissionais de saúde que trabalham em atendimento domiciliar. Objetivo: analisar a efetividade da telefonoaudiologia no atendimento domiciliar durante a pandemia de COVID-19, de acordo com a avaliação de um grupo de fonoaudiólogas(os). Método: pesquisa descritiva, realizada por meio da aplicação de questionário on-line, com amostragem não intencional, em um grupo de 137 fonoaudiólogos que atuam na cidade de São Paulo. Resultados: 58% dos profissionais utilizaram o teleatendimento durante a quarentena imposta pela situação da pandemia, destes 63% consideraram o recurso eficaz e 37% ineficaz, com os devidos argumentos para circunstanciar suas respostas. Resultados: o atendimento remoto refere-se à possibilidade de manutenção de relações e de ganhos terapêuticos dos pacientes que já se encontravam em terapia antes da pandemia, nenhum profissional considerou razoável iniciar um processo terapêutico pelo teleatendimento. Por sua vez, a percepção da não-efetividade do teleatendimento sugere, principalmente, que certos perfis clínicos dos pacientes em atendimento domiciliar (gravidade dos casos e necessidade de manejo presencial) impedem ou dificultam o atendimento remoto. Conclusão: É preciso adensar a reflexão sobre o teleatendimento, especificamente, para pacientes em atendimento domiciliar, indagando sobre as peculiaridades desses casos em termos de manejo técnico, critérios éticos e interação com pacientes, cuidadores e familiares.