bluuebunny/crossref_metadata_2025 huggingface dataset:
Juxta articular osteoid osteoma of the calcaneum: a rare case report
Authors: Upadhyay Gunjan
Published: August 2020

Osteoid osteoma of calcaneum in a juxta-articular position is a rare finding, it is most often misdiagnosed. It mimics as arthritis. Osteoid osteoma is benign bone neoplasia mostly in male in 2nd - 3rd decade of life. It has typical features of night pain relieved with salicylates. 35 years old female present with right heel pain. Mother has positive history of rheumatoid arthritis. X-ray and computer tomography were done for diagnosis. Diagnosis was made of juxta –articular position of osteoid psteoma in the calcaneum. Lesion was excised after pre-anesthesia checkup and sent for histopathology. Once investigation was done diagnosis was made as an osteoid osteoma in juxta articular position of calcaneum. Treated by excision of the lesion surgically and specimen sent for biopsy which confirm osteoid osteoma.
A controlled diaphyseal expansion osteotomy for the implantation of a wagner cone prosthesis in a stenotic femoral canal encountered in a polio limb: a case report of the technique
Authors: Kadam Tushar S. , Desai Mohan M.
Published: August 2020

Dysplastic hips pose a significant technical challenge to arthroplasty surgeons. Such deformed hips might be encountered either in congenital and developmental conditions or as sequel of neuromuscular disorders (like poliomyelitis), following infections, or after childhood surgical procedures of the hip. The scientific literature, focussing on total hip arthroplasty (THA), for coxarthrosis in patients with residual poliomyelitis, is relatively rare. Several anatomical distortions seen in dysplastic femurs are described, one of which includes an undersized diaphysis with a stenotic medullary canal. We present a case of a 28 years old male with residual poliomyelitis who underwent a cementless THA for a non united transcervical neck of femur fracture. The patient had an extremely narrow medullary canal which posed a formidable difficulty in the procedure. This was overcome by a novel diaphyseal expansion osteotomy, which enabled the implantation of Wagner Cone prosthesis. This technique, which has hitherto not been described in the literature, can significantly facilitate the implantation of an appropriately sized stem in an undersized femur while at the same time ensuring a good long-term result.
Long term outcome of ipsilateral dislocation of open displaced elbow with close shoulder dislocation: a case report
Authors: Bhardwaj Vitthal , Nahar Kuldeep
Published: August 2020

52 years old man presented with open dislocation of elbow due to road traffic accident was not complaining of another joint injury or pain was radiographed as per protocol of including the adjacent shoulder joint and incidentally discovered with anterior dislocation of shoulder was treated with close reduction of shoulder dislocation and debridement  as well as reduction and trans fixation of ulno-humeral joint with k-wires. Skin coverage later was done. Patient recovery was excellent in terms of motion at both joints. The purpose of reporting of this case is to convey a message that ipsilateral dislocation of shoulder and elbow is a very rare occurrence but do occur and a high degree of suspicion and imaging protocol can save from missing this event.
Dermatosis neglecta: a case report
Authors: Devaraj Yogesh , Mukunda Ranga Swaroop , Shale Mouryabha , Mittamedi Nikitha Reddy , Yadav Priyanka Yogananda , Sundaram Premika Meenakshi
Published: August 2020

Dermatosis neglecta or dermatitis neglecta is a condition which occurs due to inadequate cleansing of a localised area of skin resulting in the accumulation of dirt, sebum, sweat, corneocytes and bacteria. These patients do not clean the area due to various reasons like pain at the site, prior surgery, physical disability, neurological deficit, or psychiatric illness. Vigorous rubbing of the lesion with alcohol soaked gauze results in removal of the lesion. We report a case of dermatosis neglecta in a 50 year old lady with carcinoma breast following mastectomy on the right side. She did not clean the area adequately as she was scared that the area of suture after mastectomy would give way, thus resulting in hyperkeratotic lesions.
MiR-139-5p alleviates neural cell apoptosis induced by spinal cord injury through targeting TRAF3
Authors: Zhang Ziying , Shen Lifang , Yan Yingying
Published: August 2020

Spinal cord injury (SCI) is a neurological trauma that causes loss of locomotor function and sensory deficit. Previous studies showed that miRNAs play a crucial role in SCI. This study further evaluated the potential role of miR-139-5p in the neural cell apoptosis after SCI in rats. A rat SCI model was successfully established and miR-139-5p expression level in SCI rats was down-regulated compared to the sham group (sham operation group) determined by qRT-PCR. MiR-139-5p overexpression via administration with miR-139-5p agomir improved locomotor functional recovery, attenuated allodynia and hyperalgesia and alleviated neural cell apoptosis in SCI rats. In addition, TRAF3 (TNF receptor-associated factor 3 ) was identified to be a target of miR-139-5p by searching the proposed target genes in TargetScan 7.1 database. Co-transfection of miR-139-5p agomir and adenovirus of TRAF3 plasmids significantly improved functional recovery and alleviated neural cell apoptosis. Therefore, TRAF3 mediated the anti-apoptosis effect of miR-139-5p in SCI rats and miR-139-5p could be a promising candidate for SCI therapy by alleviating neural cell apoptosis through targeting TRAF3.
Pharmacist’s attitudes and knowledge of pharmacogenomics and the factors that may predict future engagement
Authors: Hundertmark Megan E. , Waring Stephen C. , Stenehjem David D. , MacDonald Danielle A. , Sperl David D. , Yapel Ann , Brown Jacob T.
Published: August 2020

Background: While pharmacists are well positioned to implement pharmacogenomic testing in healthcare systems, uptake has been limited.

Objective: The primary objective of this survey was to determine how post-graduate education and training influences pharmacist’s knowledge and attitudes of pharmacogenomic testing.

Methods: Survey questions were developed by the study team, and responses were collected electronically using REDCapTM. The electronic survey was sent to all pharmacists (n=161) within a large, multi-state healthcare system by email.

Results: A total of 75 (47%) respondents completed all aspects of the survey. The majority of respondents were female (60%), worked in acute care settings (57%), were full-time employees (80%), and worked in an urban area (85%), with many graduating in or after 2010 (43%). For post-graduate education, 36% of respondents completed a Post-Graduate Year One Residency (PGY-1), and 27% had a board certification. Those that completed a PGY-1 residency were significantly more likely to have received formal training or education on pharmacogenomics than those who had not. They also assessed their own knowledge of pharmacogenomic resources and guidelines higher than those without PGY-1 training. More recent graduates were also significantly more likely to have received formal training or education on pharmacogenomics. Additionally, pharmacists who completed a PGY-1 residency were more likely to respond favorably to pharmacogenomics being offered through pharmacy services. Pharmacists with board certification were more comfortable interpreting results of a pharmacogenomic test than those without board certification.

Conclusions: Pharmacists who have completed a PGY-1 residency or received board certification appear more comfortable with interpretation and implementation of pharmacogenomic testing.
A RELEVÂNCIA DA EXTENSÃO ACADÊMICA SOBRE A PRÁTICA RACIONAL DE MEDICAMENTOS: RELATO DE EXPERIÊNCIA
Authors: Lima Cleanny Sales , Maia Paloma Larissa De Aquino , Santos Leiliane Leite dos , Alves Shirlei Silva Barreto , Feitosa Rhaylanne De Holanda , Gama Andreza Kalline Ferreira , Koga Laryce Rafaelli Sampaio Barros , Tenório Alessandra Cristina , Silva Jaqueline Maria da , Silva Alayde Ricardo da , Soares Hugo De Lira , Da Silva Yolanda Karla Cupertino
Published: August 2020

Objetivos: Apresentar a experiência da extensão acadêmica vivenciada por estudantes do curso de enfermagem, durante um Projeto de Extensão Comunitária pela Faculdade CESMAC do Sertão.   Descrição de experiência: Trata-se de um relato de experiência baseado em ações educativas realizadas em escolas da rede pública e privada no Município de Palmeira dos índios-AL, acerca do uso racional de medicamentos. Relato: As atividades foram desenvolvidas com escolares do ensino fundamental e médio, beneficiando aproximadamente 1200 escolares entre os meses de fevereiro a dezembro do ano de 2017. Os temas foram abordados de acordo com a Política Nacional de Medicamentos e Manuais do Ministério da Saúde. Considerações finais: As atividades desenvolvidas conseguem contribuir de forma significativa para a ampliação da educação em saúde, proporcionando aos beneficiados estratégias simples que garantam o conhecimento sobre o Uso Racional de Medicamentos, além de promover a integração da faculdade e a sociedade.
PERFIL EPIDEMIOLÓGICO DE MULHERES TRABALHADORAS: ANÁLISE DOS REGISTROS NO OESTE DE SANTA CATARINA
Authors: Santin Michelly Carla , Luzardo Adriana Remião , Schneiders Milena , Ramos Alexandre Inácio , Sinski Kassiano Carlos , Da Conceição Vander Monteiro
Published: August 2020

Objetivo: Analisar o perfil epidemiológico de mulheres trabalhadoras envolvidas em acidentes e/ou doenças relacionadas ao trabalho no Oeste de Santa Catarina. Método: Estudo epidemiológico transversal descritivo de caráter observacional, com coleta de dados retrospectiva. Os dados foram coletados no período de 2012 a 2016. Resultados: Os resultados mostraram que a faixa etária predominante de mulheres acidentadas são dos 20 aos 39 anos; os tipos de lesão mais prevalentes são a lesão cortante e traumatismo; quanto aos acidentes destacam-se os com material biológico, LER/DORT, intoxicações exógenas e os acidentes de trabalho não especificados. As profissões mais notificadas são: alimentador da linha de produção, faxineiro e técnico de enfermagem. Conclusão: A notificação dos agravos à saúde do trabalhador é necessária pensando no planejamento e replanejamento das ações, programas e políticas voltadas para a saúde da mulher trabalhadora que auxiliem na prevenção de acidentes e agravos e sobretudo na redução de desfechos desfavoráveis.
ENFERMAGEM E PESQUISA NA ATENÇÃO PRIMÁRIA: CONHECIMENTOS E HABILIDADES PARA A PRÁTICA BASEADA EM EVIDÊNCIA
Authors: Schneider Luana Roberta , Pereira Rui Pedro Gomes , Ferraz Lucimare
Published: August 2020

Objetivo: identificar os conhecimentos e habilidades de enfermeiros para a prática baseada em evidência e suas práticas de pesquisa. Método: estudo realizado com 41 enfermeiros da Estratégia Saúde da Família, de um município no Sul do Brasil. A coleta de dados ocorreu por meio de um questionário, roteiro de questões auxiliares e grupo focal. Para análise utilizou-se estatística descritiva e análise de conteúdo temática. Resultados: identificou-se que há deficiência na formação acadêmica, para habilidades em pesquisa, bem como uma alta demanda de trabalho que dificulta a busca de evidências. Os enfermeiros consideraram a experiência clínica como o principal balizador de suas ações, além de que, carecem de conhecimentos e habilidades para produzir e utilizar estudos científicos. Conclusão: ainda é um desafio desenvolver a prática baseada em evidência, tencionando reflexões acerca do processo de formação profissional e da ênfase que a pesquisa tem na graduação e nos serviços de saúde.
QTL analysis and management of plant productivity in the precision agriculture
Authors: Chesnokov Yu. V.
Published: August 2020

Modern crop cultivation technologies have reached the limits of “saturation” both in the ecological (environmental pollution, suppression of the mechanisms of its self-regulation), energy (exponential growth of irreplaceable energy costs for each additional unit of production), and in production. In this regard, environmental factors (air drought, frosts, active temperatures, etc.), which cannot be optimized, are becoming increasingly important in ensuring a steady increase in the yield of cultivated plant forms. In recent decades, more and more attention has been paid to technogenic and biological systems of agriculture, based on the ecologization and biologization of the intensification processes of adaptive crop production. Such approaches are the precision agriculture system (PA) and QTL analysis. Using these approaches allows not only to ensure a steady increase in productivity due to the combined use of the advantages of precision farming and molecular genetic assessment, including the creation of new forms and varieties that are responsive to РА agricultural practices, but also to level the negative impact of abiotic and biotic environmental factors that limit the size and quality of the crop as well as plant productivity. It is shown that the strategy of adaptive intensification of crop production through the use of the TK system and QTL analysis approaches is not alternative to existing farming systems, however, it focuses modern agriculture on the growth of knowledge-intensive agricultural production as a whole. An analysis of the causes under consideration, the current unfavorable trends in modern crop production and agriculture, clearly shows their scale and long-term nature, and therefore the inevitability of the search for new priorities for intensification of crop production and agriculture, providing a qualitatively new stage of their development in the interests of man.
Fodder beet gene pool from the VIR collection: diversity, potential
Authors: Sokolova D. V.
Published: August 2020

Relevance.As a source of juicy feed for livestock, fodder beet plays a leading role among fodder root crops. It plays an important role to solve the problem of improving domestic feed production, since the production of fodder beet is the most balanced in terms of carbohydrate and protein complex. A large number of feed units from the area of sowing in a complex with a high yield, a balanced mineral complex and the possibility of long-term storage makes the crop in demand for the livestock complex in Russia. The VIR fodder beet collection has a rich gene pool and, given the lack of varieties and hybrids in the State Register of the Russian Federation, is a source of raw material for domestic breeding.

The purposeofthe study is to identify the potential of the collection of fodder beet in the most important areas of modern crop selection.

Materials and methods. The experiment involved a representative sample of 190 accessions that were grown in the vegetable crop rotation of the Research and Production Base of Pushkin Laboratories of the VIR from 2015 to 2019. Description and biochemical studies were carried out according to the VIR Guidelines.

Results.The characteristics of fodder beet cultivars with signs of high yield, productivity, resistance to abiotic and biotic factors, suitability for mechanized harvesting and storability were given. There was a manifestation of axenium resistance of the culture to cercosporosis due to morphophysiological characteristics of the leaf apparatus of plants.

Conclusions.The VIR fodder beet collection has a wide variety and well-studied gene pool, which is the potential to create the modern varieties and hybrids of crops with a complex of economically valuable characteristics, which are necessary for their high-tech production.
The patriarch of Russian vegetable growing has a centenary
Authors: Soldatenko A. V. , Pivovarov V. F. , Pyshnaya O. N. , Gurkina L. K.
Published: August 2020

The article is dedicated to the 100th anniversary of the head institution of the Federal Scientific Vegetable Center - the oldest and leading breeding organization for vegetable crops, better known in the scientific and socio-economic spheres of the Russian Federation by its historical name - VNIISSOK. The center's activity dates back to the creation in 1920 of the Gribovskaya Vegetable Breeding Experimental Station, where, under the leadership of Professor Sergei Ivanovich Zhegalov, a theoretical and practical basis for the development of domestic breeding was laid. In 1970, the experimental station was transformed into the AllUnion Research Institute of Selection and Seed Production of Vegetable Crops, and in 1992 into the All-Russian Research Institute of Selection and Seed Production of Vegetable Crops. Over the years, breeding methods have been developed and improved, including modern biotechnological methods, using molecular marking and interspecies hybridization. The results obtained during this period reflect the traditions of scientific schools and approaches laid down by scientists-breeders, seed growers, vegetable growers, flower growers, both in the field of basic research, and in the creation of varieties and hybrids of vegetable crops. The organizational and structural reform of breeding institutions carried out in 2017 contributed to the formation of the Federal scientific vegetable center (FSBSI FSVC), which includes VNIISSOK as the parent organization and 8 branches located in various ecological and geographical zones. At a new stage of development, the FSBSI FSVC continues its glorious traditions. Scientists have obtained world-class results in basic research and competitive selection achievements in priority applied research. The scientific results and structural changes that have occurred over the hundred-year period of the breeding establishment are the foundation for the further development of the vegetable science in the country.
Morphometric parameters of carrot seed quality and factors determining them.
Authors: Bukharov A. F. , Baleev D. N. , Fefelov F. O. , Eremina N. A.
Published: August 2020

Relevance.The contribution of varietal and environmental factors to the variability of the length of the endosperm and the embryo of carrot seeds was studied.

Materials and methods.The objects of study were the original seeds of Rogneda, Lubava and Chernozemochka, Chantene 2461 and Boyarynya varieties. The seeds were grown at the Voronezh and West Siberian experimental stations. The linear dimensions of the seed and endosperm were measured using a caliper. The length of the embryo was measured using a microscope (Micromed) and a video eyepiece (DCM 300 MD) at х40 magnification. Statistical processing of the research data two-factor experiment was carried out using analysis of variance. Differences in the compared parameters were considered statistically significant at p 0.05.

Results.The linear dimensions of all the main elements of seeds, as well as the index of Ie/z on average for three years significantly differed in the studied carrot varieties (P < 0.001). The maximum length of the seed (3.14±0.02 mm), the length of the endosperm (2.66±0.02 mm) and the length of the embryo (1.23±0.03 mm) on average for three years was observed in the Rogneda variety. The average coefficient of variation (V) of seed length was minimal and varied from 10.1% to 12.9%. The average values of the coefficient of variation (V) for the length of the endosperm varied in a wider range from 12.0% to 14.6%. The length of the embryo had a maximum level of variability from 18.7% in the Rogneda variety to 20.3% in the Chernozemochka variety 21.3%. The variety factor had a predominant influence (from 50.8 % to 86.5 %) on the size of the seed and its morphological elements. The contribution of the environmental conditions of the year of reproduction to the formation of morphometric parameters did not exceed 22.3 %. This allowed us to draw a conclusion about the prospects of selection and the possibility of selective changes in the morphological parameters of the seed.
Adaptive ability and stability genotypes of vegetable peas of different ripeness groups
Authors: Putina O. V. , Besedin A. G.
Published: August 2020

Relevance.The aim of the work is to define the adaptive ability and environmental plasticity of pea genotypes of different ripeness groups which were selected in Krymsk EBS VIR Branch in special conditions of Krasnodar region.

Materials and methods.Eleven pea varieties and one pea strain were sown for studying in fields of Krymsk EBS VIR Branch in 2013-2017. The area of the plot was 10 m2. Each variety was sown three times. The recording of the harvest was made in period of industrial ripeness. The share of influence of different factors on the yield of pea was defined with the help of mathematical methods. The differential ability of environmental and adaptive ability of genotypes, stability and environmental plasticity were also defined.

Results.2013 was the most unfavorable year because of the bad weather conditions. That year the pea yield was only 5/1 tons per hectare. We detected a great influence of the environmental factors (38%), the genotype factors (31) and their cooperative factors (27) on the yield of pea. The main differential ability of environmental was detected in 2016 and 2016. There were average conditions in 2014. During all years of studying there was a high effect of environmental destabilization which showed the great difference between the yields of the different genotypes. The following genotypes were found: the genotypes with a high total adaptive ability – Kudesnik 2, Vesta (k-9352) Berkut (k-8856), G-344/16; stable genotypes – Krasavchik (k-9449) and Istok (k-9353); the genotypes with an environmental plasticity – Alpha (k-7071), Vesta (k-9352), Parus (k-9350), G-344/16. The varieties which were found for breeding purposes on the totality of different characteristics of adaptability, stability and environmental plasticity are Prima (o155213) of a very early ripeness group, Vesta (k-9352) – medium-early, Parus (k-9350, leafless) –medium and the G-344/16 – medium-late.
Identification of resistant tomato genotypesusing the gamete technologies
Authors: Saltanovish T. I. , Doncila A. N.
Published: August 2020

Relevance. High temperatures are among the environmental factors that negatively affect the development of most crops including tomatoes. Thus, important condition for the realization of potential plant productivity is the heat resistance.Methods of the gamete selection in combination with classical approaches can be used to select resistant genotypes and create initial breeding material with resistance to the temperature factor.

Materials and methods.The experiments were carried out with intraspecific hybrids F4 of tomato: Elvira x Milenium, Elvira x Tomis, Elvira x Prestij, Mihaela x Milenium, Mihaela x Tomis, Mihaela x Prestij, Jubiliar х Milenium, Jubiliar x Tomis, Jubiliar x Prestij, Milenium x Elvira, Milenium x  Mihaela. Plants were grown in the field. Flowers were collected, anthers were separated, pollen was isolated. Pollen was heated for 2 or 4 hours at 43°C in the experimental variants. In the control, pollen was maintained at a temperature of 26°C. Then pollen was sown and germinated on a cultural medium. The viability was determined by the length of pollen tubes.

Results.A different reaction of pollen grains to temperature influence was established. The main sources of variability and their contribution to the variability of the pollen and seedling traits were determined. The temperature and genotype mainly determine the variability of the gametophyte and sporophyte. More than half of the hybrids combined high indicators of resistance of both pollen and seedlings, formed a larger number of flowers and better set fruits. Thus, tomato genotypes with good indicators of heat-resistance for applying in breeding have been identified based on a complex of methods for assessing the resistance of hybrids using gametophyte and sporophyte characteristics, as well as results of genetic-statistical analysis.
Vegetable growing in Azerbaijan in modern conditions
Authors: Huseynov H. G. , Jafarov I. G. , Vermeer Mink , Musaev F. B.
Published: August 2020

Relevance. Vegetable growing is a traditional sector of agriculture in Azerbaijan. The republic has all the conditions for its development, both natural and socio-economic.

Materials and methods. The aim of the research was to analyze the current state of vegetable growing in the republic, to identify the strengths and weaknesses of the industry, to determine the terms of support for producers from the state and branch science.

Results. The gross harvest of vegetables has been steadily growing in the last decades, and by 2019 amounted to 1715 thousand tons. The yield of vegetables also increased during this period from 14, 7 to 21.9 t / ha. In door production area is approximately 4800 ha. The production of greenhouse vegetables is focused on the Russian market. The bottleneck in the industry is vegetable seed production, a market with a capacity of almost 20 million euros is occupied by foreign companies. At the same time, the agricultural producers get state support in the form of subsidies and soft loans and a full tax exemption. Industry science is also developing: the Research Institute of Vegetable Production has been reconstructed and fully equipped, special training organized for vegetable growers in the Azerbaijan State Agrarian University. Further development of the industry continues through the intensification and biologization of production, expanding the range and improving product quality.
Nematodes associated with the lychee crop (Litchi chinensis) in Oaxaca, Mexico
Authors: Martínez-Bolaños Misael , Martínez-Bolaños Luciano , Martínez-Reyes Rebeca , Avendaño-Arrazate Carlos Hugo , Cruz-Chávez Marco Antonio , Gálvez-Marroquín Luis Antonio
Published: August 2020

El objetivo de esta investigación fue determinar los principales géneros de nematodos asociados a plantas adultas de litchi y su asociación con el síntoma de clorosis en Oaxaca. Para ello, de marzo a agosto de 2013, en cuatro parcelas comerciales de litchi se colectaron muestras de suelo en la zona de goteo de los árboles; se seleccionaron cinco plantas asintomáticas y cinco con clorosis de las variedades Brewster y Mauritius, en tres etapas fenológicas: floración, cosecha y desarrollo vegetativo. Aphelenchus, Ditylenchus, Helicotylenchus, Hemicriconemoides, Longidorus, Mesocriconema, Pratylenchus, Psilenchus, Rotylenchus, Trichodorus, Tylenchorhynchus, Tylenchus y Xiphinema fueron los principales géneros identificados. El mayor número de nematodos totales se obtuvo en etapa de cosecha en la variedad Mauritius (300.6, p=0.05), mientras que en Brewster fue en floración (576, p=0.05). No se observó una relación directa de la población total de nematodos y el síntoma de clorosis para las diferentes etapas fenológicas evaluadas.
Ejemplos básicos de álgebra lineal con python
Authors: Oviedo Rodríguez Katalina , Jiménez Oviedo Byron
Published: August 2020

En muchas ocasiones, durante el desarrollo de un curso, es realmente difícil (por la premura de abarcar los contenidos) dar ejemplos concretos y aplicaciones de la teoría que se ha desarrollado. Este material ofrece una presentación de algunas aplicaciones o visualizaciones que se pueden desarrollar con los contenidos vistos en curso de álgebra lineal básica, pasando por operaciones matriciales, transformaciones y vectores propios. Para el desarrollo de estos temas se utilizará el lenguaje de programación Python. Por lo cual se recomienda un conocimiento básico en programación o en Python.
Ecuaciones diferenciales ordinarias de primer orden con apoyo interactivo y videos ilustrativos
Authors: Oviedo Ugalde Norberto Gerardo
Published: August 2020

El presente libro comprende el estudio de las ecuaciones diferenciales ordinarias de primer orden mediante aspectos teóricos, ejemplos ilustrativos, ejercicios propuestos y asimismo incluye ligas hacia aplicaciones de carácter interactivo elaboradas en software Mathematica y guardadas bajo la versión gratuita  Wolfram CDF player. Las "aplicaciones interactivas" son un archivo   .cdf que se ejecuta con  Wolfram CDF player y requieren haber instalado en la computadora esta aplicación Wolfram CDFPlayer. Además de las aplicaciones en CDF player se incluye links y códigos QR que llevan a videos ilustrativos de ejercicios y ejemplos resueltos. El objetivo principal del libro es servir como material teórico-práctico en el estudio de los distintos tópicos de las ecuaciones diferenciales ordinarias de primer orden (EDO1), donde las aplicaciones en software y videos sean utilizadas como  herramienta de apoyo para complementar dicho estudio y entendimiento de una forma más dinámica e interactiva.Este trabajo se divide en seis  capítulos que comprenden el estudio de elementos básicos y teorema de exitencia y unicidad, ecuaciones diferenciales en variables separables y homogéneas, ecuaciones diferenciales exactas y con factor integrante, ecuaciones diferenciales lineales de primer orden y de Bernoulli, ecuaciones diferenciales con variable ausente y cambios de variable, finalmente el capítulo de ecuaciones diferenciales especiales (Ricatti, Lagrange y Clairaut).
Etiología y factores asociados a fototoxicidad retinal
Authors: Cristancho Chaparro Angélica María , Rey-Rodríguez Diana V.
Published: August 2020

Los efectos nocivos de la radiación solar en la piel y en la superficie ocular se conocen claramente; sin embargo, los daños fotoquímicos en la retina aún son motivo de investigación. Se ha documentado que incluso el tiempo reducido, único o recurrente de exposición a la radicación puede inducir cambios histológicos que afectan la calidad de la visión, desde alteraciones transitorias hasta maculopatías irreversibles. Pese a esto, existe limitada información sobre la prevalencia e incidencia de los casos relacionados a exposición lumínica ambiental u ocupacional. Esta investigación tuvo propósito identificar la etiología y factores asociados a fototoxicidad retinal adquirida y se utilizó como metodología de investigación la secundaria de tipo revisión narrativa. Como resultado se encontró que la liberación de radicales libres debido a la exposición directa a un estímulo luminoso puede producir daños irreversibles en los fotorreceptores y, consecuentemente, puede existir una reducción de la agudeza visual y anomalías en la percepción del color. Como conclusión, la exposición solar ha sido claramente descrita en la literatura científica como un factor asociado a fototoxicidad retinal. Sin embargo, aunque se conoce que algunas prácticas clínicas y procedimientos quirúrgicos oftalmológicos inducen lesiones toxicas por la liberación de radicales libres sobre la retina, existe escasa documentación sobre el tema
O ESTÁGIO COMO ESPAÇOTEMPO PRIVILEGIADO NA FORMAÇÃO EM EDUCAÇÃO FÍSICA: DIÁLOGOS ENTRE EPISTEMOLOGIA E HERMENÊUTICA
Authors: Rezer Ricardo
Published: August 2020

O objetivo central deste texto é refletir acerca da experiência do estágio como espaçotempo privilegiado para a formação de professores de Educação Física (EF). Procuro demonstrar teoricamente a importância da epistemologia no processo de estágio, compreendida a partir de uma orientação hermenêutica. Trabalho com a hipótese de que, a partir deste movimento teórico, poderá haver significativos impactos para a formação dos estudantes, com possíveis desdobramentos importantes para a EF escolar.
IMPACTOS DA PROVA BRASIL NAS AULAS DE LÍNGUA PORTUGUESA SEGUNDO DIZERES DE ESTUDANTES
Authors: Santos Juliano Vilmar dos , De Sousa Osmar , Torres Rosane
Published: August 2020

A Prova Brasil tem o intuito de verificar o desempenho cognitivo de estudantes nas disciplinas de Língua Portuguesa e Matemática nas séries do quinto e nono ano do Ensino Fundamental.  Com dados de reprovação e evasão, formam o índice da Educação Básica-IDEB. Este índice, segundo a literatura especializada, tem gerado diferentes tensões no contexto escolar, e tal fato motivou analisar as implicações da Prova Brasil nas aulas de Língua Portuguesa a partir das vozes de estudantes avaliados. Os dados são um recorte de duas pesquisas de mestrado já concluídas, sendo uma com o foco no quinto ano e outra com o foco no nono ano, e ambas objetivam compreender os sentidos da Prova Brasil de Língua Portuguesa para os sujeitos avaliados. Para análise dos dados, foi utilizada a teoria enunciativa do Círculo de Bakhtin, que orienta a compreensão de sujeito, sentido e gênero do discurso, e contribuições dos estudos sobre avaliações em larga escala. Este artigo tem como objetivo geral analisar as implicações da Prova Brasil na disciplina de Língua Portuguesa para as turmas de quinto e nono ano de duas escolas do Médio Vale do Itajaí. Como resultados, este trabalho apresenta que as atividades de leituras em sala de aula são orientadas para habilidades técnicas, e as relações dialógicas são esmaecidas em virtude da resolução de testes. Assim, aponta-se para a necessidade de ampliar as discussões sobre a Prova Brasil, incluindo os estudantes avaliados.
ITINERÁRIO DE UMA PESQUISA EM EDUCAÇÃO: REFLEXÕES TEÓRICO-METODOLÓGICAS NO USO DA HISTÓRIA ORAL
Authors: Nietto Rose Méri , Rabelo Giani
Published: August 2020

Neste artigo, discorremos sobre o uso da história oral como metodologia de pesquisa na área da educação, a partir de um estudo acerca do processo de formação política de esquerda de Marlene Soccas, que iniciou sua militância no período da Ditadura Civil-Militar no Brasil e continua militando até a atualidade. Para tanto, tecemos algumas considerações teórico-metodológicas sobre a história oral, descrevemos o processo das entrevistas e procuramos refletir a respeito de algumas implicações éticas inerentes a uma investigação no campo qualitativo.
MATEMÁTICA E LUDICIDADE: CAMINHOS POSSÍVEIS NOS PROCESSOS DE APRENDIZAGEM DOS ANOS INICIAIS DO ENSINO FUNDAMENTAL
Authors: Araújo Michell Pedruzzi Mendes , Gomes Chirley Dias , Ferreira Kamilla Azevedo , Drago Rogério
Published: August 2020

Este estudo traz considerações de docentes e discentes dos anos iniciais do ensino fundamental acerca da relevância da ludicidade como uma ferramenta potencializadora da aprendizagem na área da matemática. Trata-se de um estudo exploratório, embasado na concepção de aprendizagem e desenvolvimento da perspectiva sócio-histórica de Vigotski, que objetivou analisar se a ludicidade está inserida na práxis pedagógica dos docentes e suas respectivas opiniões sobre o uso do lúdico especificamente na área da matemática. Quanto aos discentes, buscou-se compreender suas concepções referentes ao “aprender matemática”: suas opiniões e expectativas sobre a inserção da ludicidade a esta disciplina. Nesse caminho foram obtidos resultados significativos, que corroboram a relevância da ludicidade como facilitadora da aprendizagem da disciplina matemática.
Às voltas com o futuro: Minhas incursões na Educação Física Escolar.
Authors: Castellani Filho Lino
Published: August 2020

Este Ensaio, construído em momento ímpar na história atual do mundo contemporâneo, onde incertezas sobre nosso presente e futuro prevalecem às análises mais otimistas sobre eles, traz reflexões acerca da Educação Física Escolar brasileira a partir das incursões no tema realizadas pelo autor ao longo de sua trajetória profissional, alicerçada em mais de quatro décadas de atuação. Em cenário de pandemia sanitária mundial motivada pelo Covid-19, e pandemônio nacional causado por desastrosas ações políticas do governo federal de nosso país, motivadoras de instabilidade de nossas instituições republicanas, coloca em evidência a política educacional e, nela, a perspectiva que redundou caber à EF Escolar ao longo do tempo passado e presente, deixando em perspectiva seu lugar em futuro próximo.
SEQUÊNCIAS NUMÉRICAS E FRACTAIS: UMA CONEXÃO POSSÍVEL?
Authors: Leivas José Carlos Pinto , Batista Bárbara Regina Da Silveira
Published: August 2020

Este artigo é um fragmento de uma pesquisa de mestrado, de cunho qualitativo, que teve por objetivo investigar quais as contribuições do uso de representação de fractais, quando utilizada para introdução de sequências numéricas, podem ser obtidas com licenciandos em Matemática. O fragmento aqui apresentado constitui-se da análise de um projeto piloto, desenvolvido em uma oficina, com três professores universitários, a fim de vislumbrar erros e acertos antes de sua aplicação aos licenciandos. Foi aplicado um questionário inicial aos professores para identificar sua formação, concluindo-se que todos têm formação em Matemática, dois atuam no Cálculo e um na Educação Básica. A construção do fractal Floco de Neve de Koch, com atividades envolvendo sequências numéricas, áreas e perímetros, permitiu concluir que é possível utilizar tal construção para introduzir o assunto nas disciplinas de Cálculo, de forma incentivadora..
PROJETO HISTÓRICO E PROJETO DE ESCOLARIZAÇÃO: CONTRIBUIÇÕES DAS TEORIAS HISTÓRICO-CULTURAL, PEDAGOGIA HISTÓRICO-CRÍTICA E ABORDAGEM CRÍTICO- SUPERADORA DO ENSINO DA EDUCAÇÃO FÍSICA
Authors: Albuquerque Joelma De Oliveira , Taffarel Celi Nelza Zülke
Published: August 2020

O objetivo do texto é responder as indagações sobre o delineamento de um possível estatuto científico da Educação Física; sobre sua natureza no contexto das teorias pedagógicas e/ou dos campos profissionais; e sobre sua especificidade no campo escolar. Fizemos isso delimitando as respostas às contribuições da teoria Histórico-Cultural, da pedagogia Histórico-Crítica e da abordagem Crítico-Superadora no ensino da Educação Física. Esta opção decorre do acúmulo teórico desenvolvido a partir dos Grupos de Pesquisa articulados pelo LEPEL/FACED/UFBA e, da formação de mestres e doutores que contribuíram no desenvolvimento de uma teoria de base marxista.
PEDAGOGIA DE MOVIMENTO : REFLEXÕES SOBRE A FORMAÇÃO UNIVERSITÁRIA DOS ESTUDANTES DA EDUCAÇÃO FÍSICA NO BRASIL
Authors: Hildebrandt-Stramann Reiner
Published: August 2020

The following contribution assumes the hypothesis that the theory of movement pedagogy is a basis for the formation of Physical Education teachers. Three fundamental topics are presented for a concept of training Physical Education teachers based on a theory of movement pedagogy: 1. the concept of professionalization with the aim of developing a capacity for didactic transformation; 2. the concept of education for the purpose of self-education; 3. the concept of movement with an appeal to the phenomenological view of movement.
EDUCAÇÃO FÍSICA CRÍTICA E EPISTEMOLOGIA: UMA ANÁLISE COMPARADA ENTRE BRASIL E CHILE
Authors: Almeida Felipe Quintão de , Doña Alberto Moreno
Published: August 2020

This paper describes, in comparison with Brazil, the critical experiences of Chilean field of Physical Education after the 1990s. In methodological terms, the study is based on a review of articles that publish on the theme in Chile. The results highlight similarities but, also, differences in the trajectory of critical pedagogy in both countries. The analysis aims to produce a common agenda for critical pedagogy of Physical Education in sense of Latin-Americans reality.
EDUCAÇÃO FÍSICA ESCOLAR: ACERCA DE UMA ESPECIFICIDADE QUE EPISTEMOLOGIA NENHUMA RESPONDE
Authors: Fensterseifer Paulo Evaldo
Published: August 2020

O presente artigo aborda a “natureza” e a especificidade da Educação Física escolar. Para isso, ensaia respostas a três questões: 1) No contexto da formação dos campos científicos, qual o delineamento de um possível estatuto científico da Educação Física? 2) No contexto das teorias pedagógicas e/ou dos campos profissionais, qual a natureza da Educação Física? e 3) Como se dá a especificidade da Educação Física no campo escolar? Diante destes desafios, o estudo realiza uma análise crítica da tentativa de resolução limitada à epistemologia, sustentando que as questões postas necessitam de um equacionamento ético-político. A título de considerações finais, o artigo aponta alguns balizadores considerados importantes para o enfrentamento do conjunto das questões, que nos desafiam no campo educacional em consonância com o campo ético-político que caracteriza a forma de sociabilidade republicana e democrática.
NATUREZA E ESPECIFICIDADE DA EDUCAÇÃO FÍSICA NA ESCOLA
Authors: Lavoura Tiago Nicola
Published: August 2020

O artigo busca discutir a natureza e a especificidade da Educação Física, bem como, possibilidades e limites de ser considerada uma disciplina do currículo escolar estruturada e desenvolvida a partir e por meio de teorizações científicas. Procura elucidar uma propositura defendendo a tese de que uma concepção de Educação Física verdadeiramente edificada sob as bases científicas do conhecimento deve ter o desenvolvimento de três dimensões distintas e inter-relacionadas de fundamentos: a filosófico-metodológica, a teoria pedagógica e a prática pedagógica. Verifica de que forma encontram-se desenvolvidos e articulados tais níveis de fundamentos na abordagem crítico-superadora da Educação Física, incitando que se faça o mesmo com as demais concepções de ensino existentes nesse campo.
THYMIDINE KINASE AS A CAUSATIVE FACTOR FOR TYPE 1 HERPES SIMPLEX VIRUS RESISTANCE AGAINST ACYCLOVIR
Authors: Martina Lefaan Yannie Febby , Setiadhi Riani
Published: August 2020

ABSTRACTBackground: Herpes Simplex Virus (HSV) infection demonstrates a high prevalence in the world. Acyclovir, one of guanine synthetic analogues, is commonly used to treat infections caused by HSV. HSV resistance against acyclovir may occur, especially in immunocompromised and immunocompetent patients, as the consequence of viral mutations. Thymidine kinase (TK) is an HSV tegument protein which plays an important role in HSV-1 resistance against acyclovir. Purpose: The purpose of this article is to review the mechanisms of TK mutation that cause HSV-1 resistance against acyclovir. Review: Acyclovir involves three stages of viral thymidine kinase phosphorylation to form acyclovir triphosphate. It prevents HSV replication by acting as a competitive inhibitor of viral DNA polymerase and a chain terminator in viral DNA synthesis. Resistance is associated with viral TK mutation that is encoded by UL23 gene. Long-term use of acyclovir may promote thymidine kinase mutation in immunocompromised and immunocompetent patients via three mechanisms, namely absolute insufficiency in TK activity (TK-negative), depletion in TK synthesis, and inability in TK phosphorylation which consequently hinders the phosphorylation of acyclovir. Herpes TK gene contains a series of cytosine and guanosine, that are important for the function and the  mutation of HSV by producing incomplete or fewer enzymes as the result of nucleotide addition or elimination in homopolymer process. Conclusion: HSV-1 resistance against acyclovir is evolved from TK mutations, in the form of TK-negative, TK low-producing, and TK altered mutants, that are unable to phosphorylate TK and accordingly disrupt acyclovir phosphorylation to convert acyclovir triphosphate. Keyword : Acyclovir, Herpes simplex virus, Resistance, Thymidine kinase
Physiotherapy in the Covid ward: Where compassion overcomes fear
Authors: Jiandani Mariya Prakash
Published: August 2020

The narrative is an account of the personal experience of a cardiopulmonary physiotherapist inside the Covid ICU, when the city of Mumbai was brought to a standstill. It describes the need to seek an opportunity to face the challenges, guided by intuition and one’s skill set to help those fighting to survive Covid. Facing a new and complex disease meant having to create guidelines for treatment, overcome the patients’ despair, and even cope with the cumbersome protective gear. But the gradual improvement in patients’ health and their joy on recovering inspired us to put in more effort with unity ,dedication and will power, standing together to face the pandemic, enabling us to realise what is required of us, now and in the future – striving to better ourselves in the science of health each day.
Age of the Upper Paleolithic sites in Kapova and Ignatievskaya caves (Southern Ural): revision and interpretations of the radiocarbon dates
Authors: Dublyansky Y.V. , Shirokov V.N.
Published: August 2020

There are two caves containing groups of wall paintings of the Upper Paleolithic age known in the Southern Ural: Kapova (Shulgan-Tash) and Ignatievskaya (Yamazy-Tash). In total, about 200 pictorial motifs have been recorded in the Kapova cave, among which there are life-like depictions of Pleistocene animals (mammoth and rhinoceros). Some 180 pictorial motifs have been found in the Ignatievskaya cave, which also show images of the Pleistocene fauna (mammoth and rhinoceros), although less realistic than those in the Kapova cave. The cultural layers have been discovered in the cave sediments at both sites. Archaeological excavations in the Kapova cave revealed multiple cultural layers which contained remains of the hearths, stone artefacts, fragments of ochre, decorations made of stone and tusk, a piece of burnеd clay cup, bone tools and animal bones (some with traces of ochre paint). In the Ignatievskaya cave, the Paleolithic cultural layer contains numerous fragments of charcoal, stone artefacts, rare fragments of ochre, decorations made from teeth of arctic fox and bison and from mammoth tusk, as well as the bones of Pleistocene animals. In the past two decades, a series of radiocarbon dates has been reported by different researchers based on the charcoal and bones from the cultural layers in both caves. Seventeen dates have been reported for the Kapova cave, including 14 Upper Paleolithic, 2 Bronze Age and 1 modern dates. The materials from the cultural layer of the Ignatievskaya cave have yielded 6 radiocarbon dates; another 3 dates were obtained directly from the charcoal used for the black paintings in the cave. Our analysis of publications, in which the radiocarbon dates from the Upper Paleolithic cultural layers of the Kapova and Ignati-evskaya caves are used, has revealed that the dating results are often reported inaccurately or incompletely, which leads to serious errors in interpretations. In particular, the incorrect use of non-calibrated radiocarbon dates as calendar ages, completely changes the paleoclimatic context of the cave occupation; for the Kapova cave, for instance, such misinterpretation shifts the dates of the cave visiting and painting from the late part of the Last Glacial Maximum and early deglaciation to the Bølling-Allerød interstadial. In this paper, we revisit the published radiocarbon ages for these two Southern Ural sites, provide practical recommendations and re-emphasize the importance for accurate and complete reporting of radiocarbon ages in publications.