bluuebunny/crossref_metadata_2025 huggingface dataset:
Prognostic criteria for the management of temporomandibular disorders using arthrocentesis with normal saline and arthrocentesis with normal saline and platelet-rich plasma
Authors: Ansar Ahmad Syed ,   1. Department of Oral and Maxillofacial Surgery, Jamia Millia Islamia Central University, New Delhi, India,   Ahmad Syed Ansar, Department of Oral and Maxillofacial Surgery, Jamia Millia Islamia Central University, New Delhi, India. E-mail: syedansarahmad@rediffmail.com, Munna Khan ,   2. Department of Electrical Engineering, Faculty of Engineering and Technology, Jamia Millia Islamia Central University, New Delhi, India, Iqbal Asif ,   3. Department of Electrical Engineering, Vivekananda Global University, Rajasthan, India, Mohammad Faisal ,   1. Department of Oral and Maxillofacial Surgery, Jamia Millia Islamia Central University, New Delhi, India, Naved Alam ,   4. Department of Computer Sciences, Jamia Hamdard, New Delhi, India, Shamimul Hasan ,   5. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia Central University, New Delhi, India
Published: November 2022

Temporomandibular joint disorders (TMDs) are ailments affecting the jaws and allied structures, resulting in many pathologies (TMJ hypermobility, internal disc derangement, bone changes, degenerative disorders, and ankylosis). Pain, clicking or crepitus, restricted range of motion, deranged jaw function, and deflected or deviated mouth opening and closing are the commonly observed manifestations in TMDs. Internal derangement refers to an aberrant relation of the articular disc to the condyle and fossa, respectively. Conventional therapies highlight the role of non-invasive conservative treatment strategies, namely joint unloading, anti-inflammatory drugs, and physiotherapy. Current literature has emphasized the use of corticosteroids and platelet-rich plasma (PRP) as treatment strategies in TMDs. This study aimed to evaluate whether intra-articular injection of PRP after normal saline lavage in TMJ minimizes the symptoms of TMDs, as compared to injection of normal saline. Thirty patients with TMD according to research diagnostic criteria (RDC) were selected. One group received arthrocentesis with normal saline, and the other group received arthrocentesis with PRP injection. The patients were assessed for pain, maximum inter-incisal mouth opening, bite force, and TMJ sounds. TMDs treated by PRP injection had slightly better results. More studies are required to substantiate the outcome. Injections of PRP were more effective in reducing the symptoms than arthrocentesis with normal saline.
Anterior accessory great saphenous vein as a cause of postoperative recurrence of veins after radiofrequency ablation
Authors: Svidersky Yrij ,   1. Department of Surgery, Institute of Postgraduate Education, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Goshchynsky Volodymyr ,   1. Department of Surgery, Institute of Postgraduate Education, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Migenko Bogdan ,   1. Department of Surgery, Institute of Postgraduate Education, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine,   Bogdan Migenko, Department of Surgery, Institute of Postgraduate Education, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine. E-mail: migenkob@gmail.com, Migenko Liudmyla ,   2. Second Department of Internal Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Pyatnychka Oleg ,   1. Department of Surgery, Institute of Postgraduate Education, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
Published: November 2022

There are problems of postoperative relapse of veins after radiofrequency ablation (RFA). The study aims to analyze the causes of postoperative recurrence of veins after RFA. 928 patients with varicose veins of the lower extremities, clinical classes C2-C4 according to the CEAP classification, were treated in the ambulatory surgery centers using RFA. The causes of varicose recurrence showed that it was caused by: a) high fusion of the anterior accessory great saphenous vein (AAGSV) with great saphenous vein (GSV) directly in the saphenofemoral junction (SFJ), which was not revealed by preoperative ultrasound (1.7%); a long stump of the GSV after the RFA (7.8%); progression of varicose disease with the small saphenous vein (SSV) and formation of new reflux associated with insufficiency of the saphenopopliteal junction (SPJ) (4.7%); d) insufficiency of perforating veins of the tibioperoneal group (Sherman, Boyd), as well as Gunter (3.8%); e) neovascularization with dilation of small vessels in the area of the saphenofemoral junction (0.97%). A comparative assessment of the quality of life (QL) after different surgery methods 3 years after implementation was carried out. Thus, QL in all patients who underwent surgery significantly improved than before surgery. However, after the RFA GSV+AAGSV, the patients had better QL by all scales than those who underwent only RFA GSV. Operations performed simultaneously on GSV and AAGSV have better functionality than GSV-only RFA.
Chemotherapy-associated oral complications in a south Indian population: a cross-sectional study
Authors: Jena Suvranita ,   1. Department of Oral Medicine and Radiology, SCB Dental College and Hospital, Cuttack, India, Hasan Shamimul ,   2. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India, Panigrahi Rajat ,   3. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha' O' Anusandhan University, Bhubaneswar, India, Das Pinali ,   1. Department of Oral Medicine and Radiology, SCB Dental College and Hospital, Cuttack, India, Mishra Namrata ,   3. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha' O' Anusandhan University, Bhubaneswar, India, Saeed Shazina ,   4. Amity Institute of Public Health, Amity University, Noida, India,   Shazina Saeed, Amity Institute of Public Health, Amity University, Noida, India. E-mail: ssaeed@amity.edu
Published: November 2022

Over the years, chemotherapy (CT) has evolved as an essential therapeutic modality for cancer, with oral manifestations frequently encountered as complications of cancer CT. Our study aimed to assess the prevalence of oral complications during CT and evaluate the significance of independent risk factors (age, gender, socio-economic status, oral hygiene practices etc). A cross-sectional study was carried out in a tertiary cancer hospital in Bhubaneswar, Odisha, India, in which a total of 138 hospitalized patients undergoing CT and fulfilling the inclusion and exclusion criteria were included. Comprehensive history and rigorous clinical examination eliciting the oral manifestations were carried out. Around 60% of patients exhibited oral manifestations. Xerostomia and lichenoid reactions were the highest and lowest recorded manifestations. Higher frequencies of oral lesions occurred in patients with breast cancer, TNM stage III, and with the administration of the docetaxel. Also, patients in the older age group, poor socio-economic status, poor quality of life, poor oral hygiene practices, and longer CT duration demonstrated more oral lesions. Individuals subjected to a dental evaluation either before or during CT exhibited a reduction in the number of oral features. Several oral complications were reported in the present study. All patients undergoing chemotherapy must receive reinforcement of oral hygiene instructions and dental evaluation before, during, and after chemotherapy treatment. The study also emphasizes the importance of oral health physician inclusion in the multidisciplinary cancer treatment team.
Evaluation of HER2/neu expression in different types of salivary gland tumors: a systematic review and meta-analysis
Authors: Javaheripour Aylar ,   1. Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran, Saatloo Maedeh Vakili ,   2. Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America, Vahed Nafiseh ,   3. Research Center for Evidence Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran, Gavgani Leili Faraji ,   3. Research Center for Evidence Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran, Kouhsoltani Maryam ,   1. Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran,   Maryam Kouhsoltani, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical sciences, Tabriz, Iran. E-mail: mkoohsoltani@yahoo.com
Published: November 2022

This study is a systematic review and meta-analysis to assess the overexpression rate of HER2 in patients with salivary gland tumors. We included peer-reviewed publications from 1995 to 2020, indexed in medical databases, using search terms such as “human epidermal growth factor receptor 2 (HER2)” and “salivary gland tumors”, and extracted relevant data. The extracted data were analyzed with RevMan 5.3 software. Intra-and intergroup post hoc analyses of outcome variables were performed using t-tests, and the rates of HER2 positivity among studies were evaluated. 80 studies were included in the analysis. The positive rates of HER2 ranged from 3.3% to 84.0% and 1% to 9% in malignant and benign subtypes, respectively. The highest HER2 overexpression rate among malignant tumors was in salivary ductal carcinomas (SDC), with a 45% positive rate (CI 95%: 21.9–70.3%). Mucoepidermoid carcinoma (MEC) had the highest positive rate of 84% (CI 95%: 74.1–90.0%). Among benign salivary gland tumors, the highest rate was found in myoepithelioma, with a positive rate of 9% (CI 95%: 1.7–33.6%). The highest rate of HER2 overexpression is present in malignant subtypes of salivary gland tumors, more specifically in salivary ductal carcinoma, mucoepidermoid carcinomas, salivary duct carcinoma in situ, and carcinoma ex pleomorphic adenoma.
Prevalence of nutrient canals in mandibular anterior intra-oral periapical radiographs (IOPARS) in patients with chronic systemic diseases – a cross-sectional study
Authors: Hasan Shamimul ,   1. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India,   Shamimul Hasan, Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India. E-mail: shasan1@jmi.ac.in, Jahan Ulfat ,   2. Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India, Saeed Shazina ,   3. Amity Institute of Public Health, Amity University, Noida, India, Kaur Mandeep ,   1. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India, Gombra Virender ,   1. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India, Rai Arpita ,   1. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India, Mansoori Shahnaz ,   1. Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India
Published: November 2022

Nutrient canals (NCs) are passages containing neurovascular bundles (blood vessels, lymph vessels, and nerves). Best visualized on mandibular anterior intraoral periapical radiographs (IOPAR), their presence is usually associated with underlying pathological such as diabetes mellitus (DM), hypertension (HTN), advanced periodontitis, calcium deficiency, tuberculosis, and disuse atrophy. This study aimed to (a) evaluate NC prevalence in patients with DM, HTN, and chronic periodontitis and (b) correlate the detection of NCs as an important preliminary screening tool for inherent systemic diseases like DM, HTN, and chronic periodontitis and as an investigative clue in age and gender determination. This cross-sectional study was conducted on 200 subjects. Patients with complaints of pain in the mandibular anterior teeth, deep dentinal caries, abrasion, and attrition were subjected to IOPAR of the mandibular anterior teeth region to assess NCs. An increased frequency of NCs in DM (84%), HTN (66%), and periodontitis (52%) with a significant p-value was observed. Most NCs were seen beyond the root apex (72.4%). A notable association between the duration of disease and the presence of NCs in the diabetic and hypertensive cohorts (p-value 0.047 & 0.012, respectively) was observed. However, we could not establish any association between the prevalence of nutrient canals with age and gender. Our study suggested that a higher frequency of NCs on mandibular anterior IOPAR may be employed as an ancillary screening and investigative support in underlying systemic disorders.
Terminological Tools to Describe the Connecting Units of the Russian Language
Authors: Kuznetsova N. V. , Pochtareva O. V.
Published: November 2022

Purpose. The article is devoted to the dynamics of theoretical understanding of connecting elements and the development of corresponding terminology in the Russian linguistic tradition. The research analyzes classic works of the founders of traditional Russian grammar as well as the latest linguistic works.

Results. The study reveals three main levels of terminology which is applied to connecting units and related to their very nature: connecting units play an important role in creating the coherence of oral and written speech, and therefore are studied in the linguistics of discourse and text; connecting units are used in the organization of simple and complex sentence, and therefore are studied in syntax; connecting units are special lexical units that receive morphological characteristics. In general, we can say that in the 20th century the part-of-speech paradigm moved to syntactic and textual ones. First linguists tried to determine the place of connecting elements among the classes of words (parts of speech), but since the middle of the 20th century the idea of the priority of syntactic function over morphological characteristic has been increasingly expressed. This tendency was clearly manifested in discursive linguistics studying coherent texts and integrating very heterogeneous phenomena on the basis of common functions.

Conclusion. Despite some inconsistency of the modern Russian terminology describing connecting elements it identifies their semantic-grammatical and functional originality.
The Expression of Certainty / Uncertainty Using the Word “Odin (One)” in Russian in Comparison with the Chinese Counterpart
Authors: Haiyan Zhou
Published: November 2022

Purpose. When discussing the phenomenon of the pronominalization of Russian numerals, the most discussed word is “odin (one)”, which is often used as an indefinite pronoun. However, in fact, the word “odin (one)” is capable of expressing a definitive meaning depending on the context and situation. In this respect, a similar phenomenon is ob served in the Chinese language. Unlike the Chinese word “一 (yi)”, which is used mainly in the function of pronouns and numerals, the Russian word “odin (one)” is able to perform the functions of different parts of speech. Based on a large number of examples, the article examines the semantic features of the opposition “certainty / uncertainty”, reveals the ways of expressing this opposition using the word “odin (one)” in the Russian language in comparison with the Chinese counterpart “一 (yi)”.

Results. The pronominalization of the numeral word “odin (one)” is a phenomenon of grammaticalization, as a result of which there is a semantic reduction, a change in grammatical categories and syntactic functions.

Conclusion. The similarity of the expression of indefinite meaning in Russian and Chinese is explained by the fact that there is no regular expression of uncertainty in both languages, the category of certainty / uncertainty is realized mainly by lexical means.
Siberia as a Symbolistic Topos: Shadows and Echoes (1904) by Pyotr L. Dravert
Authors: Mashtakova L. V.
Published: November 2022

Purpose. Pyotr L. Dravert is a Russian geologist, mineralogist, and a poet connected with Siberia and Urals by his scientific and artistic interests. The studies of Pyotr L. Dravert’s works usually proceed in two directions: either “scientific” or “Siberian”, as it was defined by Efim I. Belenkiy. Boris Ya. Buchstab pointed out the unity of two manifestations of a Dravert’s creative personality: the scientist and the poet. However, the formation of his original poetics was strongly influenced by Russian symbolism (which was noticed in works by Elena I. Dergacheva-Skop, Yury V. Shatin etc.) and this point has been little studied.

Results. The article is devoted to Dravert's first collection of poems Shadows and Echoes (Kazan, 1904) in the context of main works of Russian symbolism. Dravert's poetry can be presented as a unique case of the “Siberian text” where the semiotics of space correlates with the artistic discoveries of the Fin de Siècle.
«Social» in Social Epistemology
Authors: Shevchenko A. A.
Published: November 2022

The paper analyzes the main social contexts constituting social epistemology. It describes external so­cio-political contexts which define the framework and required procedures for open research, scientif­ic consensus and epistemic justice. However, the article argues for special importance of internal social contexts – those of knowledge production in research groups. The treatment of knowledge as a collective enterprise requires, in turn, discussion of a new set of problems: the ways and mechanisms of creating the collective subject of knowledge, ways of overcoming disagreements between individual researchers and research teams, explanation of scientific change and others. The «social turn» in epistemology calls for a careful study of these two types of interacting contexts – external and internal ones.
Heidegger on Authentic and Academic Logic
Authors: Gungov A.
Published: November 2022

Throughout his work M. Heidegger develops the theme of authentic logic contrasting it with the prevailing understanding of the character, essence and goals of academic logic. He pays special attention to the ontological justification of logic, the derivative nature of the truth, the subject-predicate structure of judgement, copula and derivation rules. He also focuses on the status of logical negation and the language ofsymbolic logic. M. Heidegger examines in detail the justificatory role of the law of identity, the relations of difference and the law of sufficient reason, and not just as logical principles but fundamental statements of logic. The conclusion of this paper is the understanding that M. Heidegger’s doctrine of authentic logic is a challenge to academic logic and a decisive step towards philosophical logic in the tradition of continental philosophy.
The Invisible Enemy in Modern Warfare
Authors: Balakleets N. A.
Published: November 2022

The author uses the conceptual and methodological apparatus of social constructivism, perspectivism and phenomenology to discuss the phenomenon of the invisible enemy in the context of modern warfare. The concept of the invisible enemy is explicated in the works of Vladimir Solovyov, Lev Karsavin, Ernst Jünger, Fyodor Stepun and other authors. The article substantiates the legitimacy of the semantic expan­sion of this concept and the possibility of its application to a number of objects. It reveals such personifica­ tions of the invisible enemy as a victim and a violent actor, a fighter and an intelligence officer, a collective and an individual subject. The relationship between the traditional identity of the combatant («the killing one – the one to be killed») and the anthropological structure «the seeing one – the visible one», which is being destroyed in modern wars, are also exposed. The inversion of the categories «visible» and «invisible» in the context of military activity is substantiated.
Effect of progressive tissue contracture on functionality of obturator prosthesis: A 3-year follow-up
Authors: Tripathi Arvind , Gupta Ashutosh , Rai Praveen , Dwivedi Ravi
Published: November 2022

Objectives:

This clinical report describes the long-term effect of tissue contracture on functionality of obturator prosthesis.

Material and Methods:

Eleven patients who underwent maxillectomy confined only to the hard palate and rehabilitated sequentially with immediate surgical obturator followed by interim closed bulb hollow obturator were included in the study. These patients were followed up every 3 months for 3 years and obturator prosthesis was relined at each appointment. All patients were evaluated for retention, resonating frequency, and percentage nasality after wearing obturator prosthesis at every 3 months following relining till 3 years.

Results:

At baseline, mean retention score ± SD (Median), % nasality, and resonating frequency were 7.25 ± 0.62 (7), 12.00 ± 0.74 (12), and 0.12 ± 0.05 (0.115) kHz, respectively. During follow-up intervals, mean retention scores showed a gradual increase from 6-month follow-up itself (7.50 ± 0.52) and reached to the peak value at 24 months (9.17 ± 0.83). With respect to change in % nasality and resonating frequency at different follow-up periods as compared to baseline, a declining trend was observed from the first follow-up (6 months). This declining trend continued in subsequent intervals too with the values reaching to their nadir at 30 months.

Conclusion:

Literature regarding detrimental effects of tissue contracture exists; however, little has been talked about the beneficial role of tissue contracture on the obturator function. This paper provides an insight about the usefulness of tissue contracture as related to obturator function and retention.
An enigmatic tale of the missed and migrated tail
Authors: Nadkarni Trupti Kedar , Kale Deepali Prakash , Shah Puja Mukeshkumar , Sardeshpande Nagendra
Published: November 2022

We, report a case of missing and migrated intrauterine device presenting as vague abdominal pain. The patient had symptoms of vaginal discharge and menstrual disturbances as polymenorrhagia and leukorrhea. She was evaluated for a suspected malignancy of the ovaries. During evaluation on pelvic CT scan, the missing and migrated Intrauterine Contraceptive Device (IUCD) was located in the small bowel and tumor markers were normal. We treated her with antibiotics for presumptive diagnosis of pelvic inflammatory disease and then posted her for the evaluation of the missing IUCD and the tubo-ovarian masses by endoscopy. The missed IUCD was seen embedded in the terminal ileum with intraperitoneal adhesions and the tubo-ovarian masses. The IUCD was removed endoscopically enterotomy of ileum which was sutured. The patient recovered well and was discharged on the 6th post-operative day.
An uncommon diagnosis of a common clinical presentation – Visceral Niemann–Pick disease
Authors: Patil Ruturaj Shivajirao , Venkatesh Sumitra
Published: November 2022

Niemann–Pick (NP) disease is a diverse spectrum of disorders, autosomal recessive in nature, characterized by failure to thrive, visceral involvement in the form of hepatosplenomegaly and neurodegenerative changes. It is caused by an inherited deficiency of acid sphingomyelinase enzyme, leading to deposition of sphingomyelin and cholesterol within the lysosome of reticuloendothelial cells of various organs. We present a 16-month-old developmentally normal, well-grown girl with progressive, insidious onset abdominal distension, and no other symptoms. She was initially misdiagnosed as sepsis, but, on further evaluation was found to be genetically proven NP disease with autosomal recessive inheritance with sphingomyelin phosphodiesterase-1 gene positivity.
Significance of retinal microcirculation disorders as predictors of glaucomatous optic neuropathy progression
Authors:   Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan, Moscow, Kurysheva N.I. , Shatalova E.O. ,   «Clinic of doctor Shatalov», Moscow region, Orechovo-Zuevo
Published: November 2022

Purpose – to assess the significance of retinal microcirculation disorders in progression of glaucomatous optic neuropathy (GON). Material and methods. In this 2-year prospective study 85 patients (124 eyes) the vessel density of the superficial parafoveal plexus (VD parafovea) and peripapillary retina (VD ppr) were measured with optical coherence tomography angiography, peripheral resistance index (RI) and blood flow velocity of the posterior short ciliary arteries (PSCA) and the central retinal artery (CRA) were studied by color Doppler flow mapping method. The predictor properties of each indicator were calculated from the area under the ROC curve (AUC). Results. The results of the study revealed a high significance of the values of relative density of the superficial plexus vessels in the parafoveolar region (VD parafovea AUC 0.70 ± 0.07), and the relative density of the microvasculature of the optic nerve head (ONH) and peripapillary retina (VD ppr 0.715 ± 0.07) as predictors of the progression of GON. Keywords: primary open-angle glaucoma, glaucomatous optic neuropathy, ocular blood flow, optical coherence tomography angiography
Reeling them in: Ph2PSiMe3 in the sequential formation of InP magic-sized clusters
Authors: Gazis Theodore , Matthews Peter
Published: November 2022

Indium phosphide magic-sized clusters (MSCs) have been identified as a key step in the growth of InP quantum dots (QDs). However, the need for elevated temperatures to form QDs from MSCs has limited our understanding of this transformation. Herein, we utilize Ph2PSiMe3 to identify additional MSC intermediate species, which absorb from 365 nm to 490 nm. Excitingly, particle growth was carried out at 100 C without the use of acidic surfactants. We show that despite being discrete, stable, and isolable sizes of MSCs, they form a reaction continuum, thus providing further insight into the growth mechanism of InP.
Photoactive p-type spinel CuGa2O4 nanocrystals
Authors: Kendall Owen , Melendez-Correa Lesly , Ren Jiawen , Ratnayake Samantha , Murdoch Billy , Mayes Edwin , van Embden Joel , Gomez Daniel , Calzolari Arrigo , Della Gaspera Enrico
Published: November 2022

Herein we report the synthesis and characterization of spinel copper gallate (CuGa2O4) nanocrystals (NCs) with an average size of 3.7 nm via a heat-up colloidal reaction. CuGa2O4 NCs have a band gap of ~2.5 eV and strong p-type character, in agreement with ab initio simulations. These novel NCs are demonstrated to be photoactive, generating a clear and reproducible photocurrent under blue light irradiation when deposited as thin films. Crucially, the ability to adjust the Cu:Ga ratio within the NCs, and its effect on the optical and electronic properties of the NCs was also demonstrated. These results position CuGa2O4 NCs as a novel material for optoelectronic applications, including hole transport and light harvesting.
A Unified Approach to the Aminoallylation of Carbonyl Compounds Through Cu-Catalyzed Enantioselective Reductive Coupling of Allenamides
Authors: Klake Raphael , Collins Stephen , Sieber Joshua
Published: November 2022

Herein, we report the development of a highly enantioselective aminoallylation reaction of both aldehyde and ketone electrophiles through the Cu-catalyzed reductive coupling of N-substituted allenes (allenamides). Through optimization of the allenamide to avoid an on-cycle rearrangement, high enantioselectivities could be obtained for a variety of ketone and aldehyde electrophiles in up to >99% ee and >98:2 anti:syn diastereoselectivities. Use of the acyclic allenamides described in this report selectively generated anti-diastereomers in contrast to cyclic allenamides that were previously shown to favor the syn form. Rationale for this change in diastereoselectivity and synthetic applications are also presented.
Lewis Structures and the Bonding Classification of End-on Bridging Dinitrogen Transition Metal Complexes
Authors: Hasanayn Faraj , Holland Patrick , Goldman Alan , Miller Alexander
Published: November 2022

The activation of dinitrogen by coordination to transition metal ions is a widely used and promising approach to the utilization of Earth’s most abundant nitrogen source for chemical synthesis. End-on bridging N2 complexes (µ-N2) are key species in nitrogen fixation chemistry, but a lack of consensus on the seemingly simple task of assigning a Lewis structure for such complexes has prevented application of valence electron counting and other tools for understanding and predicting reactivity trends. The Lewis structures have traditionally been determined by comparing the experimentally observed NN distance to the bond lengths of free N2, diazene, and hydrazine. We introduce an alternative approach here, and argue that the Lewis structure should be assigned based on the total π-bond order in the MNNM core (number of π-bonds), which derives from the character (bonding or antibonding) and occupancy of the delocalized π-symmetry molecular orbitals (π-MOs) in MNNM. To illustrate this approach, the end-on bridging N2 complexes cis,cis-[(iPr4PONOP)MCl2]2(µ-N2) (M = W, Re and Os) are examined in detail. Each complex is shown to have a different number of nitrogen–nitrogen and metal–nitrogen π-bonds, indicated as, respectively: WN–NW, Re=N=N=Re and Os–NN–Os. It follows that each of these Lewis structures represents a distinct class of complexes in which the µ-N2 ligand has a different electron donor number (total of 4e-, 6e-, or 8e-). We show how this classification can greatly aid in understanding and predicting the properties and reactivity patterns of µ-N2 complexes.
Diabetic Neuropathy
Authors: Kishor Sharma Jugal , Rohatgi Anshu , Pandita Neha
Published: November 2022

Diabetes mellitus is one of the most prevalent chronic disease in the world. Diabetes is frequently complicated by diabetic neuropathy. The most common diabetic neuropathy is chronic peripheral sensorimotor neuropathy affecting up to 50 of diabetic population. The most significant risk factors for developing diabetic neuropathy are duration of diabetes and glycemic control. The management of diabetic neuropathy is mainly focussed on controlling the risk factors and early prevention of its complications. Therefore it is necessary to make an early accurate diagnosis so that diabetic neuropathy related complications can be prevented.
Analysis of Somatic Symptoms of Major Depressive Patients
Authors: M. Mahesh* Nosenoor
Published: November 2022

Background and Aims Major depressive patients commonly report psychological and somatic symptoms SS. Reports suggest that the prevalence nature and frequency of reported SS vary depending on the somatization criteria and the way patients are interviewed. We analysed these parameters with or without structured interview in major depressive patients.Methods It was a cohort prospective study. Major depressive patients who satisfied the study criteria were randomly assigned equally for qualitative self-report and quantitative structured interview using SS scale-18 items measurements. Hamilton depression rating scale-17 items was administered to assess the depression severity. A depressive patient who reports at least one SS was counted as somatizing. Collected data were assessed using descriptive statistics and Welchrsquos t-test p lt 0.05.Results Total 510 major depressive patients of both genders aged from 18-60 years were enrolled. Of these finally 251 50.1 patients mean age 30.0 plusmn 18.6 years and 250 49.9 patients mean age 34.65 plusmn 1.6years were respectively assigned for qualitative and quantitative measurements. Prevalence of somatizing depressive patients was found to be 98.8 in qualitative 248251 and quantitative 247250 measurements. The study patients reported 9 and 18 SS to various extents respectively. Sequentially parasthetic sensation 60 149248 and headache 72.5 179247 SS were found to be frequently reported. Over 50 of depressive patients commonly reported headache parasthetic sensation fatigue body pain and heaviness in the head.Conclusions Majority of major depressive patients commonly report SS such as headache paresthetic sensation fatigue body pain and heaviness in the head among others.
Handling of expert knowledge in software product lines development with usage of repertory grids method
Authors: Gamzayev Rustam O. , Tkachuk Mykola V. , Shevkoplias Daria O.
Published: November 2022

The development of software product lines (SPL) is a promising way to create competitive software for the modern IT - market. Because of perpetual changes in user needs and the appearance of new software and hardware components for SPL, maintaining a certain level of variability at all stages of their full life cycle (FLC) becomes an actual problem. One of the most important stages is requirements engineering. To support this process it is advisable to utilize the methods of expert knowledge elicitation and analysis. Based on the recognized multilevel approach to SPL engineering proposed by K. Pohl, the research goal is to develop an approach to correct specification of variability features at the initial stages of SPL FLC. The analysis of methods to extract and process the expert knowledge is carried out, their classification is presented, and the method of repertory grid (RG) is chosen for the further usage. It allows analyzing and structuring expert knowledge in a multidimensional information space and makes it possible to consider various contextual factors that affect relevant requirements for the target SPL. The essentials of the RG method are considered and its formal description is elaborated. The examples of its usage in designing ​ “Smart House” systems which allow analyzing the technical, social and economic aspects of user requirements for software and hardware variability at the conceptual design stage of these systems are considered. As the result, a possibility to automate a process of a corresponding FODA-model creation is shown. That provides variability support at the next FLC stages of such systems.
Linguistic Analysis on Cursive Characters
Authors: Haji Chiai Mohammed
Published: November 2022

Document Analysis has major importance in Information Retrieval Systems. Dredged with vaults of paper and material documents, to protect very important information and the summaries, without losing their meaning and importance, each document need to be properly curated and processed. Ancient written documents possess many types of cursive language character sets, which are very tedious to discriminate the characters and subsequently the right meaning. To overcome the difficulties of reading the cursive language characters and prevent misunderstanding the meaning and the importance of documents, an improvised CNN [6] model to work on OCR and Tesseract API has been proposed in this work. The documents are scanned, curated and preprocessed in the forms of images. CNN are the best algorithms, hitherto in the existing AI and Deep Learning arena. CNN with OCR API could contribute to the development of efficient strategies of character recognition even with complex cursive styles. A method which is adaptable to the classification and segmentation of the text images with cursive styles is proposed I this article. Tesseract is the popular and effective OCR library with rich API that can enrich the CNN-OCR model
Quality of Life among Caregivers of Patients with Chronic Renal Failure Undergoing Hemodialysis in Duhok City
Authors: Naaman Ronak Muhammad , Ahmed Sana Thanoon
Published: November 2022

BACKGROUND: Caregivers of hemodialysis (HD) patients play a critical role in their care which can influence their quality of life. As a result, the present study aimed to examine the quality of life among hemodialysis caregivers and their relationship with some characteristics of caregivers and patients. SUBJECT AND METHODS: This descriptive cross-sectional survey was directed to assess the quality of life among family caregivers of hemodialysis patients. consecutive sampling was done and included (139) caregivers who had inclusion criteria. The period of data collection was from the 2nd of November 2021 to the 10th of February 2022. The Short Form 36 questionnaire was used to collect data. a p-value of < 0.05 was statistically significant. RESULTS: Of 139 caregivers, the mean quality of life, physical and mental component scores were 59.49 ± 22.13, 63.2 ± 25.5, and 52.7 ±27.8 respectively. The scores of the physical functioning domain had the highest score (75.4 ± 24.74), while the Energy/Fatigue domain obtained the lowest score (46.19±25.86). There was a significant negative correlation between age and the quality of life (r=-0.3858, P<0.0001). Additionally, the quality of life was higher among younger, male, single, educated, and employed caregivers at a p-value (<0.0001, =0.0003, <0.0001, =0.0022, and =0.0091) respectively. CONCLUSION: Caregivers of hemodialysis patients had a satisfactory total quality of life score. Energy/Fatigue and mental health, on the other hand, were the most affected domains. These findings emphasize the necessity of addressing the mental health of caregivers, as well as providing them with financial and psychological support
Hāpu Connectedness Project - Rengarenga Marae
Authors:   , Collins Suzanne Aroha
Published: November 2022

Marae (meeting place) are unique to Aotearoa New Zealand, but specifically to Māori culture. They embody ancestors and Māori consider them as tāonga (treasures). They are commonly on hapū (sub-tribe) and iwi (tribe) turangawaewae (place to stand) and equally important, they are central to Māori identity. To have a turangawaewae means having a place to stand, to belong and connect to that place. The dilemma for Ngāti Mōtai is that we do not have a marae, a place to stand and as a result, a vital part of our identity is missing.

Based on semi-structured interviews with descendants of Ngāti Mōtai and complemented with historical narratives derived from Treaty settlement documentation, this thesis explores the history of the traditional marae of Ngāti Mōtai, Rengarenga Marae, and its people. In doing so, I intend  to contribute to hapū aspirations to collate information about the original marae in order to begin rebuilding our marae and re-establishing our identity as a hapū of Rengarenga Marae.    

This research has found that actions of the Crown in the 1880s resulted in Ngāti Mōtai being wrongfully dispossessed of customarily owned land, in particular, Whaiti Kuranui 6C2C West A which contained significant cultural and historic sites, including Rengarenga Marae. The partition of Whaiti Kuranui in the 1880s ultimately led to the alienation of Whaiti Kuranui 6C2C West A and the separation of Ngāti Mōtai from Rengarenga Marae.    

Ngāti Mōtai are currently planning the rebuild of the marae, albeit not  on the original site but on ancestral Ngāti Mōtai land. The Ngāti Mōtai vision for Rengarenga Marae is “A puna (spring) from which to grow” and encapsulates a foundation stone where the mauri (life force) of the marae is kept safe and warm and will provide a turangawaewae for the generations to come. Whānau (family) and hapū are critical to this transformation. 

However, at present, the rebuild is largely uncoordinated. This thesis suggests that by drawing on marae/hapū-based projects from other regions there is scope for increased cohesion and collaboration amongst the hapū in order to develop innovative strategies. The aspirations that we hold for our marae can be achieved by a community-based approach. 
Biological evaluation of selected metronidazole derivatives as anti-nitroreductase via in silico approach
Authors: Adeoye Moriam Dasola , Oyebamiji Abel Kolawole , Ashiru Mojeed Ayoola , Adigun Rasheed Adewale , Olalere Olabisi Hadijat , Semire Banjo
Published: November 2022

The 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (2HMN) is a powerful antibacterial and antiparasitic drug used alongside other drugs against Helicobacter pylori infection and was investigated the effects of substituents: –OH (A), H (B), –SPh (C), –COOH (D), –NO2 (E) and –OCH3 (F) on the interactions of 2HMN with the target nitroreductase Rdxa protein for the treatment of the infection. Spartan 14 (optimization), PyMOL 1.7.4.4 (to treat downloaded protein), Autodock Tool (locate protein binding site), Autodock vina 1.1.2 (docking calculation) were used to discover the nonbonding interaction between docked complexes using SWISSADME and Pre-ADMET software. The band gaps order for the studied compounds were C < A < F < B < D < E, a probability of highest charge distribution and activity for SPh substituted derivatives and the ligands conformed to the Lipinski’s rule of five. Compounds D and E are noninhibitors and nonsubstrate for cytochrome P450 2C9, P450 2D6, P450 2C19 with the same efficient calculated binding affinity (–21.3 kJ mol–1) and inhibition constant (7.8) comparable to the standard compound A.
Eva und Adam – Adam und Eva. Das erste Paar in der Kunst
Authors: Caillieux Thea
Published: November 2022

Die biblischen Erzählungen von Adam und Eva haben auf vielfältige Weise Eingang in die abendländische Kulturgeschichte gefunden, besonders anschaulich in der europäischen Bildtradition. Über die Jahrhunderte prägen die Darstellungen der beiden ersten Menschen unsere Vorstellung davon, was ein Paar ausmacht, wie Frauen und Männer zu sein und wie sie auszusehen haben: Sie zeigen Geschlechterrollen als konstruierte Konventionen. Im Laufe der Kunstgeschichte stehen die Bilder von Eva und Adam in unterschiedlichen gesellschaftlichen Zusammenhängen. Sie dienen der Christianisierung, der Ästhetisierung, der Erotisierung, der Dämonisierung, bis sie schließlich zu Elementen des kulturellen Gedächtnisses werden, derer sich Literatur, Bildende Kunst und Werbeindustrie gleichermaßen bedienen.
CONTENT AND LANGUAGE INTEGRATED LEARNING FOR TEACHING ART HISTORY STUDENTS
Authors:   Russian State University for the Humanities, Suchugova Nataliya Yu.
Published: November 2022

The paper is devoted to the challenges of using Content and Language Integrated Learning while developing language proficiency in the Bachelor’s degree program of “Art History” and “Museology and perseverance of cultural and natural heritage objects”. This type of educating implies getting knowledge in the sphere of future profession (“History of World Art” subject in particular) concurrently with studying a foreign language. Here the foreign language is considered to be a means of education but not a purpose of it. Many advantages of this technique usage are evident: it is more natural way of communication, which helps to realize the peculiarities of the other culture, to solve professionally-oriented cases, to navigate in the information and communication space. Specialists-to-be in the field of Art History acquire and improve the skills of foreign language communication while working with the educational materials which allow them to be confident in using these skills in the professional sphere. The practice of using Content and Language Integrated Learning is analyzed by the example of the “New Insights into Art History: from Prehistoric to Medieval” course book. Basing on the knowledge acquired while working thoroughly with the authentic texts and video resources, students do their case-studies in the particular field and it allows them to work like using the foreign language in the real professional atmosphere.
Provider Initiated Testing and Counseling (PITC) Strategy Increased Coverage of HIV detection among TB Patients
Authors: Kunarisasi Sity , Putri Febianza Mawaddah , At Tauhidah Sarah
Published: November 2022

Indonesia is one of the six countries with a high burden of TB and HIV. The prevalence of TB-HIV cases at all ages is as much as 4.9%; The study aimed to provide an assessment of PITC implementation in high coverage and low coverage in HIV detection among TB patients. This study descriptive, analytic, cross-sectional with the consecutive sampling method. Data used in this research was secondary data collected from January until December 2017 conducted in 5 of the 23 cities with a high burden of TB-HIV. Using a routine reporting system by primary health care and regional health service in the district. The total sample size included TB patients registered in 5 cities 16.097 patients, 8022 patients (2.365 from low PITC, 5657 from high PITC) TB patients who had received the PITC program of this 3,5% were HIV positive. Additionally, was detected by percentage among TB patients in the high-coverage PITC area compared to in the low-coverage PITC area was 4.3:2.6. Male patients had a double risk of having HIV-positive results compared to female patients. Furthermore, the analysis also showed that productive age patients are more likely to have HIV infection compared to other age groups. Male sex aged 26 to 36 years 78-94% of them were at risk of having HIV infection. The implementation of PITC in countries with high TB ​​/ HIV burden has shown an increase in TB-HIV patient detection but still needs to be followed by ARV treatment to reduce mortality.
Mikroba Kontaminan Pada Biji Pala di Pulau Nusalaut: Karakteristik Morfologi, Frekuensi Keberadaan dan Estimasi Kuantitatif
Authors: Uruilal Costanza , Patty Jogeneis
Published: November 2022

Research objectives: 1) Identify internal factors (strengths-weaknesses) and external (opportunities-threats) that affect the home marketing mix of coconut sugar industry in Jeruklegi District. 2) Analyzing alternative marketing mix strategies for the coconut sugar home industry in Jeruklegi District. 3) Analyzing the best marketing mix strategies that are priorities to be applied to the coconut sugar home industry in Jeruklegi District. The method used is a descriptive method with the research location in Jeruklegi District which was determined intentionally (Purposive Sampling) with certain selection considerations. Involving 25 respondents of coconut sugar craftsmen. The formulation of the home marketing mix strategy for the coconut sugar industry was analyzed by SWOT (Strengths, Weaknesses, Opportunities, Threats). (Rangkuti, 2006). The results showed that internal factors were the availability of coconut trees, coconut sugar production activities were carried out continuously, the location of the coconut sugar processing business was quite strategic, the price of coconut sugar products was able to compete, the availability of experienced workers in the coconut sugar processing business, ownership of business capital. craftsmen independently, limited number of coconut trees, product quality does not yet have uniformity (taste, color and shape), lack of marketing information sources, level of production and packaging technology is still traditional, limited working capital of craftsmen, craftsmen have not done bookkeeping management and there is no group / cooperative. The position of the coconut sugar home industry in the Jeruklegi District, Cilacap Regency is in the Aggressive Region with the main strategy being the SO strategy, namely 1) Optimizing geographical conditions that support the agroclimate of natural resources and human resources of craftsmen in producing coconut sugar products continuously with competitive prices for coconut sugar products, 2) Optimizing production activities continuously in order to capture high market share opportunities both domestically and internationally with competitive prices as substitute products through partnership relationships between coconut sugar producers.