bluuebunny/crossref_metadata_2025 huggingface dataset:
Morphofunctional and morphometric features of the small intestine in experimental rats with inflammation of the abdominal cavity
Authors: Abdreshov S.N. , Yessenova M.A. , Yeshmukhanbet A.N. , Demchenko G.A. , Gorchakov V.N. , Atanbaeva G.K. , S.A. Mankibaeva
Published: June 2024

The article presents studies of the effect of fecal suspension by introducing into the abdominal cavity at the rate of 0.5 ml of a 10% solution per 100 g of animal body weight. The morpho-functional state and morphometric analyzes of the small intestine were studied in normal conditions and with inflammation of the abdominal organs by introducing fecal suspension. The results showed that inflammation of the abdominal organs led to significant changes in the wall of the small intestine, multiple hemorrhages and fibrin clots were found. In the intestine, there is a change and violation of the structures of the small intestine, the total thickness of the mucous membrane increases. Violation of goblet cells, villus height and crypt depth occur. Analysis of the study showed that the walls of the small intestine, revealed structural changes, mainly in the mucosa, submucosa and muscle membranes. The mean value of the mucosal thickness in the control group was 526.17±17.11 micrometer; submucous layer – 47.21±1.63 micrometer. Phenomena of edema, inflammatory infiltration, and separation of muscle fibers were noted in both layers of the muscular membrane. The average layer of thickness of the muscular membrane was 145.67±6.92 µm. Changes in the mucous membrane of the small intestine, at one time reflected in the structural changes in the villi-crypt of the small intestine. A violation of microcirculation in the tissues of the small intestine after the inflammatory process was revealed, which leads to aggravation of dystrophic and necrobiotic lesions of the overall state of the small intestine and is combined with the severity of the clinical picture in experimental animals.
Gold content determination in small core-samples by instrumental neutron activation analysis
Authors: Silachyov I. , V.A. Glagolev  , M.N. Kokkuzova
Published: June 2024

Application of instrumental neutron activation analysis (INAA) based on the relative method of concentration standardization was considered to determine Au content in small solid core-samples of the gold-bearing ores and rocks up to 10 g of the mass. The small core-samples about 10 mm in diameter and 22-23 mm in length were cut from the previously collected ore lumps or in-situ using a handheld drilling rig. The studied small core-samples and the polyethylene capsules of the same dimensions filled up with the corresponding certified reference material (CRM) were irradiated for 2 min by a lower density neutron flux with the help of the automated pneumatic transport system (PTS). Maximum mass and dimensions of the core-samples corresponded to the PTS design and to the conditions of its safe operation. A special device was made to fix the transport capsules in the stable counting geometry making possible to eliminate the influence of the neutron flux gradient during irradiation. Due to the substantial differences in CRM and solid sample densities, corrections for neutron self-shielding and for gamma-ray self-absorption by the core-samples were applied. The method was tried to analyze Au content in 170 small core-samples presenting different gold-bearing ores and country rocks from the Kazakhstan’s gold-barite-polymetallic deposit Maikain. This approach, rather simple methodically and requiring no unique equipment, can be used to assess gold resources together with the methods of geostatistics.
Quantifying within-matches tactical behaviors using position data and
notational analysis in soccer
Authors: Moreira Praça Gibson , Brandão Leandro , Moura Felipe , Bedo Bruno L S , Aquino Rodrigo , de Andrade André Gustavo
Published: June 2024

This study aimed to compare the collective and individual tactical positional behavior before the first goal was scored or conceded in official soccer matches. The sample comprised 50 players and 27 official matches played in Brazil during the 2020 and 2021 U-20 seasons. Global Positioning System devices were used to monitor the players’ positional data. Collective – width, length, length per width ratio, and stretching index – and individual – spatial exploration index – variables were calculated and compared between the contextual scenarios by a one-way ANOVA. Results indicated a reduction in the width after scoring a goal (p=.006) and a lower spatial exploration after conceding a goal (p<.001) compared with the draw condition. Therefore, it is concluded that goal-scoring affects the tactical positional responses of the players. Specifically, a higher width concentration, characteristic of defensive tactical behavior, is observed after scoring a goal to keep the current match status. On the other hand, players present difficulties in exploring the space after conceding a goal. The knowledge of these intrinsic game dynamics is helpful for coaches in preparing the strategies to explore changes due to goal scoring in official matches.
INFLUENCE OF NEOTECTONICS ON SEISMICITY OF THE ABINSK SEGMENT, NORTHWESTERN CAUCASUS
Authors:   Lomonosov Moscow State University, Fadeyeva Karina , Zaitsev Vladimir
Published: June 2024

Relief is one of the sources of information about neotectonic activity. Using structural-geomorphological analysis, it is possible to identify weak zones, which often reflect hidden low-amplitude faults and fracture zones under the surface of Quaternary deposits. Using structural-geomorphological analysis, planation surfaces were identified, displacement amplitudes along faults and the magnitude of neotectonic movements were determined for certain periods of time. The results obtained were compared with seismicity and the degree of inheritance was revealed. 3D computer geological modeling of the stress state also helps in identifying zones of increased neotectonic activity, as the most dangerous zones in terms of seismicity. The stress state and directions of the compression axes in the horizontal plane were calculated using the RMS Roxar software. Also, for a more detailed study of the latest geodynamics of the Abinsk segment, the frequencies of earthquakes and the amount of seismic energy released were analyzed, and frequency graphs were plotted. When comparing the growth deformations of neotectonic uplift structures and the values of the latest stress state with seismicity, their significant correlation was revealed.
PALEOGENE COLUMNAR STROMATOLITES FROM THE “KAMYSHINSKIE USHI” LOCATION (LOWER VOLGA REGION)
Authors:   ., Malyonkina Svetlana , Ivanov Aleksey
Published: June 2024

The article discusses the results of our preliminary studies of Paleocene columnar stromatolites from the “Kamyshinskie Ushi” location, near the northwestern periphery of the town of Kamyshin. The morphology, composition and features of the buildings were studied. They can be attributed to the morphological type of columnar non-branching stromatolites; fan-shaped branching stromatolites are less common; their mineral composition differs little from the host rocks and consists mainly of quartz grains cemented by silicon oxide. Dark layers are much more saturated with ore inclusions. The concentration of chromium, molybdenum, wolfram, vanadium, cobalt and nickel in dark varieties increases noticeably, which confirms their stromatolite origin. The deposition settings of their formation remain controversial.
Social Trauma vs Adverse Childhood Experiences of Ukrainian Children of Forced Migrants
Authors: Klymenko Olena , Salnikova Svіtlana , Dembitskyi Serhii
Published: June 2024

The purpose of the article is to study the key problems that Ukrainian children of forced migrants face and experience events of this nature, which are classified as social trauma. The authors reflect on studies focused on migrant children and emphasize taking into account the conditions under which this migration took place, namely: forced spontaneous migration as a result of Russia's military aggression against Ukraine. Considering the scale of forced migration of Ukrainians both in terms of number and prevalence, the increase in the number of social problems caused by migration is an important factor in social transformations in Ukraine and EU countries. The authors emphasize the fact that migrant children go through a unique experience that affects their childhood, provoking the emergence of the “social cryptomnesia” phenomenon and requiring the mobilization of adaptive resources. Aspects of children's application of old social practices in new (sometimes existential) socio-cultural conditions are highlighted separately, which complicates the process of adaptation, integration and acculturation. The authors analyse the traumatic impact on socialization of such negative phenomena as stigmatization, cultural shock, and ethnic dissociation. The research results presented in the article confirm the high level of traumatic experiences of children of forced migrants who survived shelling, life in shelters, occupation, filtration camps, poverty, hunger, etc. It is important to study adaptation resources that help children adapt to new living conditions.
Geliştirilmiş EfficientNet-B0 mimarisi ile Helikobakter Pilorinin Teşhisi
Authors: Alıcı Karaca Demet , Baştürk Akay Bahriye , Karaboga Dervis , Baştürk Alper , Nalbantoğlu Özkan Ufuk
Published: June 2024

Kansere bağlı ölümlerde önde gelen türlerden olan mide kanserine çevresel ve genetik birçok faktör sebebiyet verebilir. Başlıca risk faktörlerinden birisi ise midede gastrit ve ülsere neden olan helikobakter pilori bakteri virüsüdür. Bu virüsün tespit edilebilmesi için histopatolojik değerlendirme yapılmaktadır. Manuel yapılan bu işlem iş yükü, zaman kaybı ve subjektif değerlendirmeden kaynaklı patologlar arası görüş ayrılıklarına sebebiyet vermektedir. Tanı sürecini hızlandırmak ve hastaya zamanında tedavi uygulayarak yaşam süresini uzatmak amacıyla otomatik sistemlere ihtiyaç duyulmaktadır. Bu çalışmada son yıllarda başarımı artarak devam eden derin öğrenme mimarisi histopatolojik tam slayt görüntüden helikobakter pilorinin varlığını teşhis etmek için kullanılmaktadır. Mide biyopsi görüntülerini içeren halka açık DeepHP veri seti kullanılarak Helikobakter pilorinin tanısında uçtan-uca bir derin öğrenme modeli olanEfficientNet-B0 uygulanmıştır. Ayrıca, ağın özellik çıkarma yeteneğini geliştirmek amacıyla son zamanlarda literatüre sunulan çeşitli dikkat mekanizmaları (Etkili Kanal Dikkat, Frekans Kanal Dikkati Ağı, Kapılı Kanal Dönüşümü, Evrişimsel Blok Dikkat Modülü ve Basit, Parametresiz Dikkat Modülü) derin modele entegre edilerek model başarımı üzerindeki etkileri incelenmiştir. Yapılan analizler sonucunda, Frekans Kanal Dikkat Ağı entegre edilen EfficientNet-B0 mimarisinin, histopatolojik görüntülerden helikobakter pilorinin tanısında 0.99835 doğruluğa ulaştığı görülmüştür. Buna göre, önerilen model literatürde yer alan modellerin DeepHP veri seti üzerinde ürettiği sonuçlardan çok daha üstün bir sonuç üretmiştir ve hastalığın tanısında umut vaat edicidir.
Reputação online em festivais: um estudo sobre a perceção de qualidade dos serviços da Oktoberfest Blumenau
Authors: Amorim Tainá Zutter , Quadros Cynthia Morgana Boos , Limberger Pablo Flôres , Pereira Tércio
Published: June 2024

Os festivais são um exemplo do que é influenciado diretamente pela reputação online. A Oktoberfest de Blumenau (SC) possui uma reputação online formada por milhares de avaliações de turistas, o que pode ser decisivo para que os próximos turistas a frequentem. Nesse contexto, o objetivo deste trabalho é analisar a reputação online em festivais, com foco na Oktoberfest Blumenau. A metodologia deste trabalho é de cunho exploratório e descritivo. A primeira etapa foi qualitativa, sendo categorizada e interpretada a partir das dimensões propostas pela escala SERVQUAL. Posteriormente uma análise quantitativa da as ocorrências de comentários online. As informações foram obtidas nas plataformas online TripAdvisor e Facebook no ano de 2019. Os resultados apontam que a maioria dos comentários sobre a festa é referente a experiência de conhecer e desfrutar da cultura alemã em uma estrutura adequada, o que proporciona além de uma ótima gastronomia variada, muita diversão. Fica evidente que, mesmo com comentários negativos, no geral a reputação online é positiva o que influencia a vinda de novos visitantes.
A produção científica sobre mulheres viajantes: uma análise dos periódicos brasileiros de turismo
Authors: Silva Priscilla Teixeira da , Oliveira Natália Araújo de , Gabriel Ketrin Cristina , Almeida Helena de Jesus
Published: June 2024

Este estudo tem por objetivo sistematizar o conhecimento científico produzido em periódicos brasileiros com Qualis A1 a B3 da área do Turismo sobre mulheres, com ênfase, em particular, em mulheres viajantes. A metodologia utilizada caracteriza-se como descritiva e bibliográfica. Primeiramente, a partir de uma consulta realizada na plataforma Sucupira da Capes, foram levantados 12 periódicos brasileiros com Qualis A1 a B3, na área de Administração de Empresas, Ciências Contábeis e Turismo que contivessem a palavra “turismo” ou “hospitalidade” em seu título. Em seguida, foi realizada uma busca nas edições disponíveis nos endereços eletrônicos dos 12 periódicos. No total foram consultados 4.385 artigos, publicados entre os anos de 1990 e 2020, entre os quais, 33 (0,75%) continham algum dos termos: mulher (es); woman; women; mujer (es); feminino; feminina; feminidade em seus títulos e/ou palavras-chave. Destes, apenas dois são pesquisas sobre mulheres viajantes, representando 0,04% do total de artigos publicados nos periódicos consultados. São trabalhos recentes, publicados nos anos de 2019 e 2020, e com investigações realizadas em mídias socias (Facebook e blog). Os artigos abordam, especialmente, as limitações encontradas na mobilidade das mulheres viajantes, bem como evidenciam a importante contribuição das tecnologias na articulação das mulheres.
Luz, Câmera, Ação! A hospitalidade virtual no ensino remoto emergencial durante a pandemia da COVID-19
Authors: Da Cruz Andrade Davi Alysson , Bouças da Silva David Leonardo , Neves Gabrielle Pereira das , Viana Ana Caroline Monte Negro
Published: June 2024

Este artigo objetivou identificar as atitudes que revelam a prática da hospitalidade nas aulas online de uma universidade federal do Nordeste brasileiro. Esta pesquisa foi quantitativa, exploratória e descritiva com 187 alunos dos cursos de Turismo e Hotelaria da referida instituição. Os dados foram coletados com ajuda da plataforma SurveyMonkey, entre julho e agosto de 2020, por meio de um questionário contendo dimensões e variáveis da hospitalidade propostas na literatura consultada, e baseado nas experiências dos autores com atividades acadêmicas online durante a pandemia da COVID-19. As cinco dimensões da hospitalidade definidas foram: Personalização; Recepção Calorosa; Relacionamento Especial; Acessibilidade; Ambiente e Organização. Os resultados indicam que as dimensões consideradas de maior relevância – Acessibilidade e Personalização – são aquelas que tratam de atitudes exclusivas docentes, reforçando seu protagonismo na mudança das aulas presenciais para o Ensino Remoto Emergencial (ERE). Por outro lado, a dimensão apontada como menos relevante – Recepção Calorosa – congrega mais comportamentos discentes, fato que demonstra menor reconhecimento do alunado acerca do seu papel na construção da hospitalidade nas aulas online. Este estudo contribui como debate da hospitalidade virtual no ERE, indicando práticas para uma relação mais hospitaleira, entre professores e alunos, nas aulas online.
Evidências da Relação entre Tecnologia e Interação com os Funcionários na Jornada do Cliente de Parques Temáticos
Authors: Silva Fabíola Fernandes , Barreto Leilianne Michelle Trindade da Silva
Published: June 2024

Atualmente, os clientes interagem com as empresas, incluindo as que atuam nas áreas de turismo e hospitalidade, por meio de inúmeros pontos de contato em vários canais e mídias, resultando em jornadas do cliente mais complexas. Essas mudanças exigem das empresas que querem oferecer aos clientes criação e entrega de experiências positivas integrar várias funções de negócios, entre elas a tecnologia da informação (TI) e recursos humanos. Dessa forma, este estudo tem o intuito de analisar as evidências da relação entre tecnologia e interação com os funcionários na jornada do cliente de parques temáticos. Para tanto, a investigação apresentou caráter descritivo e exploratório, com abordagem qualitativa. A pesquisa foi realizada a partir do conteúdo gerado pelo usuário (CGU) dentro do ciberespaço Tripadvisor.com, sendo o método de pesquisa aplicado a Análise de Conteúdo. Os principais resultados da pesquisa demonstraram que a tecnologia e a interação com o funcionário interferem na jornada do consumidor de parques temáticos e que o ser humano e a tecnologia precisam coexistir nos pontos dessa jornada. As reflexões advindas das implicações teóricas e empíricas desse estudo podem auxiliar gestores de parques temáticos a compreender quais comportamentos e experiências estão ganhando força, permitindo, assim, realizar investimentos direcionados a eles.
Germany as a Nuclear Power?: How Nuclear Taboo Shaped the Discourse on West German Nuclearization
Authors:   Institute of East and West Studies Yonsei University, Philipp Windhab Philipp Windhab , Kim Jaechun
Published: June 2024

A disinformation campaign by the Adenauer administration in the 1950s has led the public to believe that West Germany has never had any intentions on gaining nuclear capabilities. This interpretation is not accurate, as modern research shows and opens a new area of research to be explored. Modern literature on the topic however has mostly been dealing with the problem of German nuclearization from an historical background. While there has been some research on the topic from an international relations perspective, such research has been conducted mostly from a realist perspective. Although the realist perspective has some merits, it is lacking in explanatory power when it comes to the words and behavior of German policy makers and politicians. Constructivist theory of the ‘nuclear taboo’ offers a good supplementary explanation for inner political dynamics during the 1950s and early 1960s. This research examines debates in the Bundestag related to the nuclearization of West Germany during those periods and takes a closer look at what and how congresspeople discussed West Germany going nuclear. It proves that nuclear taboo embraced by the congresspeople discouraged West Germany’s nuclearization.
HCNs’ cultural intelligence as a promoter of knowledge sharing in foreign subsidiaries: Exploring multiple mediation mechanisms
Authors:   Institute of East and West Studies Yonsei University, Shin Ha Jung , Pak Yong Suhk
Published: June 2024

As the strategic importance of knowledge that resides in host county nationals (HCNs) increases, this study begins with the motivation to advance our understanding of HCNs’ cultural intelligence (CQ) as a prominent promoter of their knowledge sharing. Drawing on social identity theory, we hypothesized a serial mediation effect of (i) relationship between HCNs and expatriates, and (ii) HCNs’ organizational identification. We empirically tested the model with 414 responses collected by HCNs working for 16 foreign subsidiaries in Korea. Results from structural equation model show that high CQ of HCNs is positively related to the relationship between expatriates and HCNs. This positive relationship between two parties is found to facilitate organizational identification of HCNs. Lastly, it was shown that HCNs’ organizational identification has a positive impact on their active knowledge sharing within foreign subsidiaries. Moreover, we found that the impact of HCNs’ CQ on their knowledge sharing is fully mediated by two suggested mediators. This research contributes to investigating the role of CQ in knowledge management from the perspective of HCNs, rather than following extant studies that give more focus on expatriates. We also proposed the full mediation model that identifies the process by which HCNs’ knowledge sharing is promoted in a multicultural work environment.
PRIMARY HEADACHES IN ADOLESCENTS WITH DEPENDENCE ON COMPUTER GAMES AND SOCIAL NETWORKS. APPROACHES TO THE TREATMENT AND PREVENTION OF MIGRAINE IN CHILDREN AND ADOLESCENTS
Authors: Kostyuchenko Yu. , Potupchik T. , Evert L. , Shubina M. , Chudinova O.
Published: June 2024

A review of data on the main types of primary cephalgia in adolescents (headache tension and migraine), their prevalence, classification, clinical manifestations, basic principles of treatment and prevention is presented. The results of our own study, which showed a closer relationship between the frequency of occurrence and clinical features of these types of pathology with the presence of addiction to computer games and social networks in adolescents, are included. Of the 5195 surveyed adolescents, 8.1% had an to social media addiction, 10.5% had a Gaming Addiction, including 7.7% moderate and 2.8% severe. The authors come to the conclusion that it is necessary to analyze the characteristics of Internet use and content consumed by adolescents for early diagnosis, treatment and prevention of primary cephalalgia associated with the presence of gaming addiction and dependence on social networks, highlight approaches to the treatment of migraine in adolescents.
EFFECTIVENESS AND SAFETY OF CHONDROGUARD THERAPY IN PATIENTS WITH ENDOCRINE PHENOTYPE OF OSTEOARTHRITIS
Authors: Vasilieva L. , Starodubtseva I. , Evstratova E. , Tkacheva O. , Dudinskaya E. , Sarvilina I.
Published: June 2024

Objective. To evaluate the efficiency and safety of therapy with parenteral chondroitin sulfate (CS) Chondroguard®, CS-Bioactive© (Bioiberica S.A.U., Spain); ZAO “Sotex” PharmFirm, Russia) in patients with Stage II knee osteoarthritis (KOA), grade 1 knee functional insufficiency (FI), and type 2 diabetes mellitus (T2DM). Subjects and methods. A 50-day comparative pilot study involved 80 patients with Kellgren-Lawrence Stage II KOA, grade 1 FI, and T2DM, who were divided into 2 groups; Group 1 (a study group; n=40) received CS (Chondroguard®, 100 mg/ml, intramuscularly, every other day; the first three injections of 1 ml each; if they were well tolerated; starting from injection 4 of ml each; the treatment cycle was 25 injections for 50 days) and therapy for T2DM and its complications; Group 2 (a comparison group; n=40) took oral symptomatic slow acting drugs for osteoarthritis (SYSADOA) agents containing CS, glucosamine, unsaponifiable compounds of avocado and soybean, and therapy for T2DM and its complications. On study days 0 and 50, the investigators calculated in the patients the scores of the visual analogue scale (VAS), WOMAC index, the Lequesne index, those of the WHO and the Narango Therapy Safety Scales, assessed the parameters of the blood hormonal and metabolic profile, free radical oxidation (FRO), antioxidant system (AOS), and the levels of blood proinflammatory factors. Results. In Group 1, therapy with CS was well tolerated and was accompanied by a reduction in pain intensity on VAS at rest and in motion, in functional restrictions on the WOMAS index and the Lequesne index, as well аs by a decrease in blood proinflammatory markers (С-reactive protein, interleukin 6 and 1β, leptin, lipocalin-2), in the concentration of fasting and postprandial glucose, HbA1c, С-peptide, insulin-like growth factor-1, and in FRO-AOS activity (malondialdehyde, protein oxidative modification, superoxide dismutase) as compared with the indicators in Group 2. Conclusion. Chondroguard® was shown to be effective and safe in the combination therapy in patients with Stage II endocrine KOA phenotype, grade 1 FI, and T2DM.
Effect of Equamer on cardialgia and psychoautonomic status in woman with metabolically healthy obesity, estrogen deficiency, and hypertension in the late fertile period
Authors: Khabibulina M. , Shamilov M.
Published: June 2024

A study group included 74 women with metabolically healthy obesity (MHO), estrogen-deficiency, and hypertension in the late fertile period (LFP); their mean age was 39.60±3.51 years) who was prescribed the antihypertensive agent Equamer as part of combination therapy. A control group consisted of 75 women with MHO in the LFP (their mean age was 39.50±3.49 years) with the normal level of estradiol and without hypertension. The study group was found to have an association of hypoestrogenism with psychoautonomic disorders, hypersymptopaticotonia, and cardialgia. After 6 months of therapy, the agent Equamer was shown to have a positive effect on the psychoautonomic status, the episodes of cardalgia in patients with estrogen-deficiency, MHO and hypertension in the LFP. Equamer has a high efficiency, is well tolerated by the patients (no adverse events were seen in the study), levels off the clinical manifestations of hypertension, normalizes blood pressure, lowers the body mass index, and exerts a complex harmonizing effect on a female organism.
ATTITUDE TO HEALTH, PREVENTION AND MEDICAL CARE: GENDER ASPECT
Authors: Akimov А. , Kayumova M. , Novoselov A. , Lebedev E. , Bessonova M.
Published: June 2024

Recent studies have been focused on studying new relationships that demonstrate associations of non-conventional risk factors for cardiovascular diseases in female populations, not only from the standpoint of a possible reduction in cardiovascular risks, but also the search for new technologies for preventive intervention, involving the study of the influence of parameters that reflect the attitude of the population to health, prevention and medical care. At the same time, the number of such studies at the population level, especially on the territory of the Russian Federation, is currently rare. However, their demand due to the consistently high levels of cardiovascular morbidity and mortality in the world and in Russia is obvious and is positioned by leading cardiologists and epidemiologists.
Effect of glycated hemoglobin on the recurrence rate of paroxysmal atrial fibrillation in patients with type 2 diabetes mellitus who used different glucose-lowering agents
Authors: Ignatenko G. , Bagriy А. , Prikolota О. , Prikolota A. , Mikhailichenko Е. , Golodnikov I. , Bagriy O. , Kotova K.
Published: June 2024

Objective. To evaluate the effects of glycated hemoglobin (HbA1c) levels during
different glycemic control regimens on the occurrence of paroxysmal atrial
fibrillation (AF) episodes in patients with concurrent type 2 diabetes mellitus (DM)
(T2DM).
Subjects and methods. The randomized prospective open-label study involved
73 patients (41 males and 32 females; their mean age was 61.4±10.5 years) with
paroxysmal AF and T2DM. According to the prescribed therapy, the patients were
divided into groups: Group 1 included 39 patients who received combination
therapy with dapagliflozin (at a dose of 10 mg/day) and metformin; Group 2
consisted of 34 patients who took sulfonyl urea agents and metformin. The groups
were matched for the main clinical and laboratory parameters.
Results. At a HbA1c level of 6.5–7.0%, the patients had significantly less
frequently episodes of AF in both groups compared to those having an HbA1c 7.0–
7.5% (30.4% versus 77.8%). After treatment, episodes of AF were significantly
less frequently seen in Group 1 than in Group 2 (33.3% versus 58.8%; р<0.05).
Conclusion. It is desirable to achieve target HbA1C values of 6.5–7.0% (in the
absence of contraindications) in patients with paroxysmal AF concurrent with
T2DM during sugar-lowering therapy. It is recommended that sugar-lowering
agents, such as dapagliflozin, with an organ-protective potential, should be used.
DESIGN OF CARBON MONOXIDE (CO) MEASUREMENT TOOL USING SIM900A AND SOLAR PANEL BASED ON WEMOS D1 MINI
Authors: Annisa Risa , Saleh Khairul , Bahtiar Muhamad Rizki , Muallifah Naqiyatun
Published: June 2024

With abundant natural resources, East Kalimantan has a major environmental issue: forest fires. Several cases in East Kalimantan currently garner pros and cons regarding relocating Indonesia's new capital to the region. Fires in peatlands are usually dominated by smoldering processes, resulting in the highest emissions of carbon monoxide (CO) particles. Carbon monoxide gas is odorless, colorless, and tasteless, making it difficult to detect, yet highly toxic, and can cause illness in humans. Considering the dangers caused by CO gas, this research aims to create a CO gas detector to determine air pollution conditions in the environment. This research uses an MQ-7 sensor to detect CO gas, where the data is processed into parts per million (ppm), Wemos D1 Mini as the microcontroller, and SIM900A module as the data transmitter to the website. The system uses solar panels to fulfill its power needs independently. The device's characteristics can measure CO levels ranging from 51.55 to 907.61 ppm with an average accuracy rate of 95.10% and precision of 97.18%. The model performed well overall.
Applications to Support Smart Learning Environments in Project-Based Cooperative Learning Models in Java Programming Courses and Applied in Science
Authors: Melyanti Rika , Ayu Fitri , Mardainis Mardainis , Henda Zupri , Herianto Herianto
Published: June 2024

This research paper proposes the development of an application to support an intelligent learning environment in a project-based cooperative learning model on Java programming courses. The application is built using the Laravel framework where the end result later lecturers can easily see the student portfolio of each learning access on the java programming course. An intelligent learning environment will enable students to learn from their experiences, adapt to new input, and perform project tasks already assigned to lecturers. This application will also help teachers in groups that are adapted from the cooperative learning model of the STAD type. The proposed application will be designed to make it easier for teachers to form groups based on the ability of students from high, medium and low, so that the groups formed are not homogeneous groups. This application will be useful for a variety of study programmer that have practical programming courses devised. This paper will discuss the benefits of cooperative learning, project-based learning, and intelligent learning environments in the context of Java programming courses. It will also provide insights into the proposed application development process.  This application facilitates communication and discussion among students in a group that is easily connected with their lecturer, so that the lecturer can also monitor the activity of the group members. This paper will conclude with a discussion of the potential impact of the proposed applications on the field of education and the future in the learning environment.
Instrumentos de política, subsidios y valor de la producción agrícola: México, Brasil y Chile
Authors: Olvera-Avendaño Aminta , Martínez-Bautista Humberto , Salas-González José María , Zavala-Pineda María Jesica , Sagarnaga-Villegas Leticia Myriam
Published: June 2024

Las transferencias, bajo la modalidad de subsidios, configuran una intervención gubernamental dirigida a impulsar el desarrollo económico. Estas se brindan a través de diversos instrumentos que inciden en la producción y el comercio. La organización para la cooperación y el desarrollo económicos clasifica estos instrumentos en categorías de mayor a menor distorsión. En su estrategia de desregulación del mercado mundial, incentiva el empleo de estos últimos en la política agrícola. Sin embargo, el efecto de esta recomendación sobre el valor de la producción agrícola ha sido escasamente investigado. Este trabajo evaluó la relación entre el monto de apoyo en diferentes instrumentos de política agrícola empleados y el valor de la producción de productos agrícolas subsidiados (VpS) en México, Brasil y Chile durante el periodo 1995-2020, a través de un modelo de regresión lineal múltiple con el procedimiento de eliminación etapa por etapa hacia atrás (stepwise backward). Los resultados muestran que los rubros de las transferencias que resultaron relevantes para explicar el VpS en México fueron: almacenamiento, mercadeo y otra infraestructura física, apoyos basados en superficie y número de animales, servicios de extensión, seguridad e inspección de productos agrícolas e infraestructura institucional (p< 0.05), en Brasil fueron: investigación, precios de mercado y educación (p< 0.05) y en Chile fueron: investigación, almacenamiento, mercadeo y otra infraestructura física y reestructuración de fincas (p< 0.05). Se debe destacar que todos los instrumentos con efecto significativo sobre el VpS están clasificados como menos distorsionantes, con excepción del apoyo a precios de mercado presente en Brasil.
Paces desde abajo en Colombia
Authors: Hernández Delgado Esperanza
Published: June 2024

Paz y construcción de paz son conceptos y realidades interdependientes. La investigación para la paz ha identificado distintas realidades de paz de este país, y dentro de estas un significativo universo de iniciativas civiles de paz. Aquí ubicamos las iniciativas civiles de paz de base social, que son realidades propositivas y esperanzadoras para Colombia.
The Importance of Brand Equity and Branding in Terms of Product / Service Preference and Internationalization: An Analysis of Civil Air Transportation with Marketing Strategies
Authors: Aydın Ahmet
Published: June 2024

In this study, by emphasizing the importance of brand equity and branding in terms of internationalization, the effects of quality brand perception and a strong brand positioning on product/service preference in civil airline transportation have been tried to be explained in line with service marketing strategies and through descriptive content analysis method. The data collected from the literature about civil air transport companies with the traditional compilation method have evaluated in detail through descriptive content analysis. According to the results obtained, it has been understood that the customer-consumer satisfaction factors to be obtained from the purchased products/services and their differences from competing businesses should be explained to customers/consumers in detail, and suggestions have been made to civil airline companies in order to be more preferred and gain customer loyalty.
Specification of Lethal Concentration (LC50) of Boron Toxicity on Daphnia pulex (Leydig, 1860) via Using Probit Model
Authors: Yeşilbudak Burcu
Published: June 2024

Statistical models used in toxicity experiments have been quite useful tools in interpreting the organism's susceptibility, exposure response, amount of tolerable concentration, and function of tolerance time. In order to determine and evaluate the toxic effects of boron on Daphnia pulex (Leydig, 1860), different boron concentrations considered to be tolerable in aquatic ecosystems were tested for D. pulex. Percentage mortality rates at different boron concentrations and probit regression estimates at these concentrations were investigated through the static method. Probit analysis in this study revealed that rising boron concentrations led to mortality, and that finding was statistically significant with P value. These results indicate that the use of episodic boron, which enters the aquatic ecosystem through natural or unnatural means, should be planned due to its potential for stress or toxicity situations on organisms.
AGRICULTURAL SCIENCE: YESTERDAY, TODAY, TOMORROW
Authors:   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, KHLESTKINA E.K. , KHASBIULLINA O.I. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, DAKHNO O.A. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, EFREMOVA O.S. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, SOKOLOVA E.A. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, GAINATULINA V.V. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, PETRUSHA E.N. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources, RUSAKOVA E.A. ,   N.I. Vavilov All-Russian Institute of Plant Genetic Resources
Published: June 2024

Abstracts of the reports presented at the International Scientific and Practical Conference “Agricultural Science: Yesterday, Today, Tomorrow”, dedicated to the 90th anniversary of the commencement of agricultural science in Kamchatka, which was held in Kamchatka on July 26–27, 2023 (hereinafter referred to as the Event/Conference), are published. The Conference was hosted by the Kamchatka Research Institute of Agriculture, a multifunctional specialized scientific institution that provides scientific support for the agroindustrial complex in Kamchatka Territory. In 2023, the Institute was incorporated as a branch into the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) and acquired the status: Kamchatka Research Institute of Agriculture – branch of VIR. The Event was attended by representatives of the largest scientific research and higher education institutions of the Russian Federation and the Republic of Belarus, managers of agricultural enterprises in Kamchatka Territory, executives from the Ministry of Science and Higher Education of the Russian Federation, and other officials. This publication is addressed to a wide range of experts in agriculture, including those employed at the agro-industrial complex enterprises, researchers, lecturers, postgraduate students, and undergraduates from universities and colleges.
Taxpayer's Perception on the Adoption of E-Filling System in Tanzanian Cities
Authors: Munisi Hawa , Mulamula Heri , Omar Fatma
Published: June 2024

Electronic filing system (e-filling) is a recent phenomenon in Tanzania. The Tanzanian Government, through its revenue authority, TRA, in the year 2020 introduced a tax e-filling system for the effective collection of various types of taxes. Since the inception of the tax e-filling system in Tanzania, only a few studies have focused on retailers' perceptions of using such a system. This study adopted a descriptive survey design conducted in Tanzanian cities using a set of closed-ended questionnaires to a random sample of 423 taxpayers. The main finding of the study showed that perceived usefulness and user satisfaction significantly influence users' adoption intention of e-filling ([β = 0.396, p < 0.000; β = 0.343, p < 0.000, respectively]). Additionally, the study indicated a broad discrepancy between the advantages of tax e-filling to taxpayers, hence downplaying its usage/adaptability. The study recommended that awareness-raising campaigns and training be initiated to understand the tax e-filling system better. Policy-wise, the study contributes to the Income Tax Act, Cap. 332 R.E., 2019, the Tanzania Development Vision 2025, and the National Strategy for Growth and Reduction of Poverty I & II.
Sürdürülebilir Enerji Politikaları Kapsamında Yeşil Enerji Kullanımına Yönelik Mali Teşvikler: İzmir ve Manisa Üretim Firmaları ile Anket Çalışması
Authors: Gerger Atakan , Çetin Gerger Güneş , Şavlı Devrim
Published: June 2024

Küresel ısınmanın etkilerinin her geçen gün daha da artması başta Avrupa Birliği üye ülkeleri olmak üzere küresel ölçekte fosil kaynaklı enerji kaynaklarının kullanımının kademeli olarak azalmasına yol açmaktadır. Bu durum; yenilenebilir enerji kaynaklarına yönelimi artırmış ve döngüsel ekonomiyi ön plana çıkarmıştır. Yeşil enerji kaynaklarına yönelim aynı zamanda enerji politikalarının değişmesine neden olmakta ve yeşil enerji kaynaklarına yatırım yapmayı teşvik etmektedir. Bu yönelim uluslararası küresel örgütlerlerin önlemleri ile birlikte firmaların da yeşil dönüşümünü hızlandırmıştır.
Bu araştırmada Türkiye’de ve dünyada sürdürülebilir enerji kaynaklarına ve karbonsuz enerjiye yönelik mali teşvikler incelenmiştir. Mevzuattaki güncel düzenlemeler ile birlikte Avrupa Yeşil Mutabakatına uyumu güçleştiren sorunlar ve başarı faktörleri anket yardımı ile değerlendirilmiştir. Örneklem evreni, Manisa Organize Sanayi Bölgesinde yer alan firmalar ve Ege Bölgesi Sanayi Odasına bağlı İzmir’de yer alan firmalar olarak belirlenmiştir.
Araştırmada gerçekleştirilen analizler sonucunda yeşil enerji kullanımı açısından firmaların durumları, tutumları ve sürdürülebilir ekonomi açısından mevcut sorunları ve farkındalıkları incelenmiştir. Araştırmada örneklem grubunda yer alan firmaların yeşil enerji kullanımına ilişkin mali teşvikler hakkında yeterli bilgiye sahip olup olmadıkları tespit edilmiştir.
Syntactical Pattern of News Headlines in The Jakarta Post and The Diplomat Reporting The 2024 Indonesian Presidential Election
Authors: Panji Artha Nur Restia , Kadir Puspa Mirani , Wagiati Wagiati
Published: June 2024

The research discussed the syntactical pattern in news headlines between two different-country background news report channels, The Jakarta Post and The Diplomat reporting the same case, that was Indonesian Election 2024. The data source consists of twenty different news titles from both channels published on June 6, 2023. A qualitative approach with a descriptive analysis is used in this research. The Syntax underlying tree pattern by Van Valin et al (1997) serves as the framework for this research. The research findings showed that it was found that the Indonesian channel, Jakarta Post, have all sentential headline pattern in their ten news with nine simple sentences and one complex sentence, while The Diplomat which is from America, have eight sentential headlines and two phrased pattern from their ten news with simple sentence form at all headlines.
Occupational health and safety in flour Mills: A research and risk assessment
Authors: Özbakır Okan
Published: June 2024

Flour mills are one of the workplaces with occupational health hazards due to irregular workplaces and environments where insufficient attention is paid to workers’ safety. In this context, considering the extent of difficulties faced by workers in flour mills, hazards and risks that could affect the health and occupational safety of workers were investigated in a sample of flour mills in Iğdır province. The data obtained as a result of the research was ranked using the matrix method. The study identified 68 specific risks, of which 38% were identified as unacceptable risks requiring immediate action and 33% as risks requiring medium-term action. The results show that among the factors negatively affecting the health of workers, the respiratory hazard level of wheat dust with RS:15 (l:3, s:5) and the explosion hazard with RS:20 (l:4, s:5) occupy significant positions. Despite the emphasis on the importance of hygiene standards, serious deficiencies were identified, such as RS:20, which is considered high risk. In addition, the presence of many machines, such as conveyors, silos, compressors and rollers, was found to increase the risks on the system in the range of RS:20-25, which could lead to serious injury or death. Bacteria and microorganisms, such as RS:16-18, proliferate due to the low availability of personal hygiene facilities in the factory. For each identified risk, the necessary control measures are proposed and it is emphasized that protective measures should also be taken even after the implementation of these measures. Among the factors that negatively affect the health of workers in flour mills are the lack of use of personal protective equipment, working in dirty conditions, the presence of elements that can cause respiratory problems, as well as injuries related to carrying heavy loads on slippery floors and using unprotected machinery.
Exploring the Neuroinflammatory Pathway in Epilepsy and Cognitive Impairment: Role of HMGB1 and Translational Challenges
Authors: Ngadimon Irma Wati , Seth Eryse Amira , Shaikh Mohd. Farooq
Published: June 2024

Neuroinflammation has emerged as a shared molecular mechanism in epilepsy and cognitive impairment, offering new insights into the complex interplay between immune responses and brain function. Evidence reveals involvement of High mobility group box 1 (HMGB1) in blood-brain barrier disruption and correlations with epilepsy severity and drug resistance. While anti-inflammatory treatments show promise, translating these discoveries faces challenges in elucidating mechanisms and developing reliable biomarkers. However, strategically targeting neuroinflammation and HMGB1-mediated inflammation holds therapeutic potential. This review synthesises knowledge on HMGB1 and related biomarkers in epilepsy and cognitive impairment to shape future research and treatments targeting these intricate inflammatory processes.
Brain Slice Derived Nerve Fibers Grow along Microcontact Prints and are Stimulated by Beta-Amyloid(42)
Authors: Steiner Katharina , Humpel Christian
Published: June 2024

Background: Alzheimer’s disease is characterized by extracellular beta-amyloid plaques, intraneuronal tau neurofibrillary tangles and excessive neurodegeneration. The mechanisms of neuron degeneration and the potential of these neurons to form new nerve fibers for compensation remain elusive. The present study aimed to evaluate the impact of beta-amyloid and tau on new formations of nerve fibers from mouse organotypic brain slices connected to collagen-based microcontact prints. Methods: Organotypic brain slices of postnatal day 8–10 wild-type mice were connected to established collagen-based microcontact prints loaded with polyornithine to enhance nerve fiber outgrowth. Human beta-amyloid(42) or P301S mutated aggregated tau was co-loaded to the prints. Nerve fibers were immunohistochemically stained with neurofilament antibodies. The physiological activity of outgrown neurites was tested with neurotracer MiniRuby, voltage-sensitive dye FluoVolt, and calcium-sensitive dye Rhod-4. Results: Immunohistochemical staining revealed newly formed nerve fibers extending along the prints derived from the brain slices. While collagen-only microcontact prints stimulated nerve fiber growth, those loaded with polyornithine significantly enhanced nerve fiber outgrowth. Beta-amyloid(42) significantly increased the neurofilament-positive nerve fibers, while tau had only a weak effect. MiniRuby crystals, retrogradely transported along these newly formed nerve fibers, reached the hippocampus, while FluoVolt and Rhod-4 monitored electrical activity in newly formed nerve fibers. Conclusions: Our data provide evidence that intact nerve fibers can form along collagen-based microcontact prints from mouse brain slices. The Alzheimer’s peptide beta-amyloid(42) stimulates this growth, hinting at a neuroprotective function when physiologically active. This “brain-on-chip” model may offer a platform for screening bioactive factors or testing drug effects on nerve fiber growth.