bluuebunny/crossref_metadata_2025 huggingface dataset:
The oral bioaccessibility and gingival cytotoxicity of metal(loid)s in wild vegetables from mining areas: Implication for human oral health
Authors: Tian Wen , Gao Peng , Zong Da-Peng , Liu Jian-Jun , Zhang Meng-Yan , Wang Cheng-Chen , Wang Zhen-Xing , Wang Jian-Min , Niu You-Ya , Xiang Ping
Published: November 2022

Background

Heavy metal(loid)s are frequently detected in vegetables posing potential human health risks, especially for those grown around mining areas. However, the oral bioaccessibility and gingival cytotoxicity of heavy metals in wild vegetables remain unclear.

Methods

In this study, we assessed the total and bioaccessible Cr, As, Cd, Pb, and Ni in four wild vegetables from mining areas in Southwest China. In addition, the cytotoxicity and underlying mechanisms of vegetable saliva extracts on human gingival epithelial cells (HGEC) were studied.

Results

The Plantago asiatica L. (PAL) showed the highest bioaccessible Cr, As, Cd, and Pb, while the greatest bioaccessible Ni was in Taraxacum mongolicum (TMM). The Pteridium aquilinum (PAM), Chenopodium album L. (CAL), and TMM extracts decreased cell viability, induced apoptosis, caused DNA damage, and disrupted associated gene expressions. However, PAL extracts which have the highest bioaccessible heavy metals did not present adverse effects on HGEC, which may be due to its inhibition of apoptosis by upregulating p53 and Bcl-2.

Conclusion

Our results indicated that polluted vegetable intake caused toxic effects on human gingiva. The heavy metals in vegetables were not positively related to human health risks. Collectively, both bioaccessibility and toxic data should be considered for accurate risk assessment.
The causal association between iron status and the risk of autism: A Mendelian randomization study
Authors: Chen Li , Guo Xingzhi , Hou Chen , Tang Peng , Zhang Xin , Chong Li , Li Rui
Published: November 2022

Emerging evidence indicates a connection between serum iron levels and autism, but the underlying causal association is yet unclear. Thus, we performed two-sample Mendelian randomization (MR) analysis to evaluate the causal link between iron status on autism, using genetic instruments (p < 5E–08) strongly associated with iron status (N = 48,972), including serum iron, ferritin, transferrin levels, and transferrin saturation. Summary statistics of autism was obtained from two independent studies conducted by Psychiatric Genomics Consortium (PGC, Ncases = 5,305, Ncontrols = 5,305) and FinnGen Consortium (FC, Round six, Ncases = 344, Ncontrols = 258,095), respectively. Using the inverse-variance weighted (IVW) method, the combined results of PGC and FC demonstrated that genetically determined serum transferrin level was significantly associated with an increased risk of autism [odds ratio (OR) = 1.16, 95% CI: 1.03–1.30, p = 0.013]. There was no significant causal effect of serum iron (OR = 0.99, 95% CI: 0.72–1.37, p = 0.951), ferritin (OR = 0.88, 95% CI: 0.47–1.64, p = 0.676), and transferrin saturation (OR = 0.89, 95% CI: 0.72–1.09, p = 0.252) on autism. No obvious pleiotropy was found in this MR study. Taken together, our findings highlight that elevation of serum transferrin level might be associated with a high risk of autism, suggesting a potential role of iron deficiency in autism development. Future studies are warranted to clarify the underlying mechanism, which will pave a new path for the prevention and treatment of autism.
The 8p11 myeloproliferative syndrome: Genotypic and phenotypic classification and targeted therapy
Authors: Li Taotao , Zhang Gaoling , Zhang Xiaoling , Lin Hai , Liu Qiuju
Published: November 2022

EMS(8p11 myeloproliferative syndrome, EMS) is an aggressive hematological neoplasm with/without eosinophilia caused by a rearrangement of the FGFR1 gene at 8p11-12. It was found that all cases carry chromosome abnormalities at the molecular level, not only the previously reported chromosome translocation and insertion but also a chromosome inversion. These abnormalities produced 17 FGFR1 fusion genes, of which the most common partner genes are ZNF198 on 13q11-12 and BCR of 22q11.2. The clinical manifestations can develop into AML (acute myeloid leukemia), T-LBL (T-cell lymphoblastic lymphoma), CML (chronic myeloid leukemia), CMML (chronic monomyelocytic leukemia), or mixed phenotype acute leukemia (MPAL). Most patients are resistant to traditional chemotherapy, and a minority of patients achieve long-term clinical remission after stem cell transplantation. Recently, the therapeutic effect of targeted tyrosine kinase inhibitors (such as pemigatinib and infigratinib) in 8p11 has been confirmed in vitro and clinical trials. The TKIs may become an 8p11 treatment option as an alternative to hematopoietic stem cell transplantation, which is worthy of further study.
Ultrasound super-resolution imaging for differential diagnosis of breast masses
Authors: Zhang Ge , Lei Yu-Meng , Li Nan , Yu Jing , Jiang Xian-Yang , Yu Mei-Hui , Hu Hai-Man , Zeng Shu-E , Cui Xin-Wu , Ye Hua-Rong
Published: November 2022

Objective

Ultrasound imaging has been widely used in breast cancer screening. Recently, ultrasound super-resolution imaging (SRI) has shown the capability to break the diffraction limit to display microvasculature. However, the application of SRI on differential diagnosis of breast masses remains unknown. Therefore, this study aims to evaluate the feasibility and clinical value of SRI for visualizing microvasculature and differential diagnosis of breast masses.

Methods

B mode, color-Doppler flow imaging (CDFI) and contrast-enhanced ultrasound (CEUS) images of 46 patients were collected respectively. SRI were generated by localizations of each possible contrast signals. Micro-vessel density (MVD) and microvascular flow rate (MFR) were calculated from SRI and time to peak (TTP), peak intensity (PI) and area under the curve (AUC) were obtained by quantitative analysis of CEUS images respectively. Pathological results were considered as the gold standard. Independent chi-square test and multivariate logistic regression analysis were performed using these parameters to examine the correlation.

Results

The results showed that SRI technique could be successfully applied on breast masses and display microvasculature at a significantly higher resolution than the conventional CDFI and CEUS images. The results showed that the PI, AUC, MVD and MFR of malignant breast masses were significantly higher than those of benign breast masses, while TTP was significantly lower than that of benign breast masses. Among all five parameters, MVD showed the highest positive correlation with the malignancy of breast masses.

Conclusions

SRI is able to successfully display the microvasculature of breast masses. Compared with CDFI and CEUS, SRI can provide additional morphological and functional information for breast masses. MVD has a great potential in assisting the differential diagnosis of breast masses as an important imaging marker.
Recommendations of the clinical target volume for the para-aortic region based on the patterns of lymph node metastasis in patients with biliary tract cancer
Authors: Long Xin , Wu Han , Yang Lei , Xu Hui , Dai Jing , Wang Wenbo , Xia Ling , Peng Jin , Zhou Fuxiang
Published: November 2022

Background

Even though the clinical target volume (CTV) in biliary tract cancer (BTC) patients has been proposed by several previous studies, the para aortic CTV for BTC is still not well-defined. The objective of this study was to determine the precise delineation of the para aortic CTV for BTC according to the distribution pattern and failure pattern of lymph nodes.

Methods

Computed tomography (CT)-, magnetic resonance imaging (MRI)- or positron emission tomography-computed tomography (PET-CT)-generated images of patients with BTC from 2015 to 2020 were analyzed retrospectively. The distribution patterns of lymph nodes in different regions were summarized. The diagnosed para aortic lymph nodes (PALNs) were manually mapped to standard axial CT images. The asymmetric CTV expansions from the para aortic were defined according to the distance from the volumetric centre of lymph node to the most proximal border of aorta.

Results

A total of 251 positive lymph nodes were found in the study cohort (n = 61 patients, 92 PALN). All PALNs were projected onto axial CT image of the standard patient. PALNs were concentrated in the 16a2 and 16b1 regions, and the involvement rates were 17% and 13% respectively. Therefore, the upper boundary of 16a2 and the lower boundary of 16b1 were defined as the cranial and caudal border of para aortic CTV, respectively. For the study cohort, the mean distance from the volume center of all lymph nodes in 16a2 and 16b1 to the proximal border of the aorta was 9 mm (range 4-24) in the front, 7 mm (range 3-14) on the left, and 12 mm (range 5-29) on the right. For the validation cohort (n=19 patients, 56 PALN), the mean distance from the center of the lymph node to the border of the aorta were both 10 mm on the left (range 5-20) and right (range 6-23). The mean distance in front of the aorta was 9 mm (range 5–23). Finally, a CTV expansion from the aorta of 18 mm in the front, 12 mm on the left, and 24 mm on the right resulted in 96% (73/76) coverage of PALNs in the study cohort. At the time of the validation, the described CTV could include 96% (47/49) of recurrent PALNs in the validation cohort.

Conclusions

The involvement rates of PALNs in 16a2 and 16b1 were the highest. Based on the distribution of PALNs, a new para-aortic CTV was defined to construct a more accurate target volume for adjuvant radiotherapy in BTC.
Efficacy and safety of glycyrrhizic acid preparation treating comorbid liver injury in COVID-19: A systematic review
Authors: Liu Xu , Tian Xia , Ma Zhipeng , Chen Jiali , Huang Qingsong , Gao Peiyang , Zhang Chuantao
Published: November 2022

Background: No specific drug for COVID-19 has been found, and many studies have found that different degrees of liver injury often occurred after infection with COVID-19. Glycyrrhizic acid preparation (GAP) has been frequently used clinically, often combined with conventional treatments such as antiviral therapy, to improve the prognosis of COVID-19 and patients’ liver function.

Aims: To critically review and analyze clinical evidence on the efficacy and safety of GAP in the treatment of COVID-19 alone and COVID-19 with comorbid liver injury.

Methods: A systematic literature review was performed following a sensitive searching strategy that examines all articles published in “WHO COVID-19 Research Database,” “Cochrane Library,” “VIP,” “CNKI,” “Wanfang,” and “CBM” from 2020 to July 2022. Articles were evaluated by peer reviewers and used Joanna Briggs Institute (JBI) critical appraisal tools to complete the assessment of the risk of bias.

Results: Ten clinical studies were finally included, involving 598 patients with COVID-19, of whom 189 were confirmed to be with comorbid liver injury. The main GAPs used are diammonium glycyrrhizinate and magnesium isoglycyrrhizinate, which have shown efficacy in improving liver function, inhibiting inflammation, and enhancing immunity. We are still seeking more related research.

Conclusion: Glycyrrhizic acid preparations (mainly diammonium glycyrrhizinate and magnesium isoglycyrrhizinate) have a considerable clinical effect on improving liver function in patients with COVID-19 alone or with comorbid liver injury. Further studies on the use of GAP in the treatment of COVID-19 with comorbid liver injury and its mechanism are still needed.

Systematic Review Registration: [www.crd.york.ac.uk/prospero], identifier [CRD42021234647].
Bayesian probability updates using sampling/importance resampling: Applications in nuclear theory
Authors: Jiang Weiguang , Forssén Christian
Published: November 2022

We review an established Bayesian sampling method called sampling/importance resampling and highlight situations in nuclear theory when it can be particularly useful. To this end we both analyse a toy problem and demonstrate realistic applications of importance resampling to infer the posterior distribution for parameters of ΔNNLO interaction model based on chiral effective field theory and to estimate the posterior probability distribution of target observables. The limitation of the method is also showcased in extreme situations where importance resampling breaks.
Mining of chicken muscle growth genes and the function of important candidate gene RPL3L in muscle development
Authors: Lin Shudai , Xian Mingjian , Ren Tuanhui , Mo Guodong , Zhang Li , Zhang Xiquan
Published: November 2022

The birth weight of chickens does not significantly affect the weight at slaughter, while the different growth rate after birth was one of the important reasons for the difference in slaughter weight. Also, the increase in chickens’ postnatal skeletal muscle weight is the main cause of the slaughter weight gain, but which genes are involved in this biological process is still unclear. In this study, by integrating four transcriptome datasets containing chicken muscles at different developmental times or different chicken tissues in public databases, a total of nine candidate genes that may be related to postnatal muscle development in chickens were obtained, including RPL3L, FBP2, ASB4, ASB15, CKMT2, PGAM1, YIPF7, PFKM, and LDHA. One of these candidate genes is RPL3L, whose 42 bp insertion/deletion (indel) mutation significantly correlated with multiple carcass traits in the F2 resource population from Xinghua chickens crossing with White Recessive Rock (WRR) chickens, including live weight, carcass weight, half eviscerated weight, eviscerated weight, breast meat weight, wing weight, leg muscle shear force, and breast muscle shear force. Also, there was a very significant difference between different genotypes of the RPL3L 42 bp indel mutation in these trains. Further experiments showed that RPL3L was highly expressed in chicken skeletal muscle, and its overexpression could promote the proliferation and inhibit the differentiation of chicken myoblasts by regulating ASB4 and ASB15 expression. Our findings demonstrated that the RPL3L 42 bp indel may be one of the molecular markers of chicken weight-related traits.
Callus induction and transcriptomic analysis of in vitro embryos at different developmental stages of peony
Authors: Zhu Xiangtao , Zhu Huijun , Ji Wen , Hong Erman , Lu Zeyun , Li Bole , Chen Xia
Published: November 2022

The efficient induction of peony embryogenic callus is of great significance to the improvement and establishment of its regeneration technology system. In this study, the in vitro embryos of ‘Fengdanbai’ at different developmental stages were selected as explants, the effects of different concentrations and types of plant growth regulator combinations on the induction and proliferation of embryonic callus at different developmental stages were investigated, and comparative transcriptome analysis of callus with different differentiation potentials were performed to explore the molecular mechanisms affecting callus differentiation. The results showed that the germination rate of 90d seed embryo was the best, which was 94.17%; the 70d and 80d cotyledon callus induction effect was the best, both reaching 100%, but the 80d callus proliferation rate was higher, the proliferation rate reached 5.31, and the optimal induction medium was MS+0.1 mg·L–1NAA+0.3 mg·L–1TDZ+3 mg·L–12,4-D, the callus proliferation multiple was 4.77. Based on the comparative transcriptomic analysis, we identified 3470 differentially expressed genes (DEGs) in the callus with high differentiation rate and low differentiation rate, including 1767 up-regulated genes and 1703 down-regulated genes. Pathway enrichment analysis showed that the “Phenylpropanoid biosynthesis” metabolic pathway was significantly enriched, which is associated with promoting further development of callus shoots and roots. This study can provide reference for genetic improvement and the improvement of regeneration technology system of peony.
The heat shock factor GhHSFA4a positively regulates cotton resistance to Verticillium dahliae
Authors: Liu Lu , Wang Di , Zhang Chao , Liu Haiyang , Guo Huiming , Cheng Hongmei , Liu Enliang , Su Xiaofeng
Published: November 2022

Heat shock factors (HSFs) play a crucial role in the environmental stress responses of numerous plant species, including defense responses to pathogens; however, their role in cotton resistance to Verticillium dahliae remains unclear. We have previously identified several differentially expressed genes (DEGs) in Arabidopsis thaliana after inoculation with V. dahliae. Here, we discovered that GhHSFA4a in Gossypium hirsutum (cotton) after inoculation with V. dahliae shares a high identity with a DEG in A. thaliana in response to V. dahliae infection. Quantitative real-time PCR (qRT-PCR) analysis indicated that GhHSFA4a expression was rapidly induced by V. dahliae and ubiquitous in cotton roots, stems, and leaves. In a localization analysis using transient expression, GhHSFA4a was shown to be localized to the nucleus. Virus-induced gene silencing (VIGS) revealed that downregulation of GhHSFA4a significantly increased cotton susceptibility to V. dahliae. To investigate GhHSFA4a-mediated defense, 814 DEGs were identified between GhHSFA4a-silenced plants and controls using comparative RNA-seq analysis. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that DEGs were enriched in “flavonoid biosynthesis”, “sesquiterpenoid and triterpenoid biosynthesis”, “linoleic acid metabolism” and “alpha-linolenic acid metabolism”. The expression levels of marker genes for these four pathways were triggered after inoculation with V. dahliae. Moreover, GhHSFA4a-overexpressing lines of A. thaliana displayed enhanced resistance against V. dahliae compared to that of the wild type. These results indicate that GhHSFA4a is involved in the synthesis of secondary metabolites and signal transduction, which are indispensable for innate immunity against V. dahliae in cotton.
Psychological health, wellbeing and COVID-19: Comparing previously infected and non-infected South African employees
Authors: Hill Carin
Published: November 2022

Most COVID-19 and work-related well-being research is centred around the adverse effects on employees’ psychological well-being and is not focused on the work-related well-being of those infected by SARS-CoV-2. Furthermore, COVID-19 and work-related well-being research is generally aimed at healthcare workers. The current study focused on investigating the difference in the level of burnout, anxiety, depression and stress between previously infected and uninfected participants. This study used a cross-sectional survey design and non-probability quota sampling to collect data. A retrospective pre-post design was used to determine the difference between the level of burnout of the participants before and after infection. Working adults in South Africa were targeted and divided into those previously infected (n = 245) and those not yet infected with COVID-19 (n = 221). Participants completed questionnaires relating to burnout, depression, anxiety, and stress. A comparison of means revealed a significant increase in burnout after being infected. Infected participants had significantly higher burnout, anxiety, depression, and stress levels than their non-infected counterparts. Emotional exhaustion, withdrawal, and stress were the most prevalent psychological ill-health problems. The results of this study indicated that a SARS-CoV-2 infection has a detrimental impact on participants’ psychological well-being and mental health compared to their own initially reported levels of burnout before infection, as well as compared to the levels of burnout, depression, anxiety and depression of the non-infected participants. Based on the findings, specific recommendations to industrial psychologists were made to manage the psychological impact of COVID-19 on employees.
Broadcasters’ expertise and consumers’ purchase intention: The roles of consumer trust and platform reputation
Authors: Li Jie , Zheng Ruyi , Sun Haiqin , Lu Jiaoying , Ma Wenbo
Published: November 2022

Following the outbreak of COVID-19, farmer-assisted live streaming has become a hot topic in China. In this manuscript, we explore the ways in which broadcaster and platform characteristics jointly influence consumers’ purchase intention. To examine our hypotheses, we distributed questionnaires to 261 Chinese consumers who viewed farmer-assisted live streaming. Correlational analyses, regression analyses, and confirmatory factor analyses were conducted to examine our hypotheses. The results show that broadcasters’ expertise is positively related to consumer trust and that platform reputation moderates this relationship. In addition, consumer trust mediates the positive relationship between broadcasters’ expertise and consumer purchase intention. Furthermore, the theoretical and practical implications of these findings are discussed.
The ABC of academic procrastination: Functional analysis of a detrimental habit
Authors: Svartdal Frode , Løkke Jon Arne
Published: November 2022

Academic procrastination – habitually delaying work with academic tasks to the extent that the delays become detrimental to performance, wellbeing, and health – represents a substantial personal, systemic, and societal problem. Still, efforts to prevent and reduce it are surprisingly scarce and often offered as treatment regimens rather than preventive efforts. Based on the principles of functional analysis and a broad examination of factors that are important for academic procrastinatory behaviors, this paper aims to describe a strategy for analyzing individual controlling conditions for procrastination and give parallel advice on how to change those controlling conditions. Both are ideographic, allowing for individual and dynamic analyses of factors responsible for instigating and maintaining procrastination, as well as tailor-made remedies that address controlling conditions in preventive and curative efforts to reduce procrastination. Although functional analysis integrates well with important research findings in the procrastination field, this approach suggests new criteria for identifying procrastinatory behaviors and an alternative model for analyzing their control conditions. We conclude that a functional approach may supplement procrastination research and efforts to prevent and alleviate this detrimental habit.
Predictors of entrepreneurial intentions: The role of prior business experience, opportunity recognition, and entrepreneurial education
Authors: Tian Hongyun , Akhtar Shamim , Qureshi Naveed Akhtar , Iqbal Shuja
Published: November 2022

Entrepreneurship and its influence on the development of the economy are significant in competitive global advancement. Entrepreneurs need entrepreneurial intentions to improve the commercial environment of the country. Therefore, studying entrepreneurial intentions’ influencing predictors is vital for business development. We collected data from small and medium-sized enterprises (SMEs) employees of the developing country and used partial least square structured equation modeling to analyze the proposed relationships. The results assist the literature extension and practically contribute to developing entrepreneurs’ intentions through education and opportunity recognition. The findings aid the institutions in improving course planning and establishing practical business setups. This study facilitates the government’s ideas of commencing entrepreneurial businesses through proper resource provisions for the entrepreneurs.
Hearing the physical condition: The relationship between sexually dimorphic vocal traits and underlying physiology
Authors: Chen Shitao , Han Chengyang , Wang Shuai , Liu Xuanwen , Wang Bin , Wei Ran , Lei Xue
Published: November 2022

A growing amount of research has shown associations between sexually dimorphic vocal traits and physiological conditions related to reproductive advantage. This paper presented a review of the literature on the relationship between sexually dimorphic vocal traits and sex hormones, body size, and physique. Those physiological conditions are important in reproductive success and mate selection. Regarding sex hormones, there are associations between sex-specific hormones and sexually dimorphic vocal traits; about body size, formant frequencies are more reliable predictors of human body size than pitch/fundamental frequency; with regard to the physique, there is a possible but still controversial association between human voice and strength and combat power, while pitch is more often used as a signal of aggressive intent in conflict. Future research should consider demographic, cross-cultural, cognitive interaction, and emotional motivation influences, in order to more accurately assess the relationship between voice and physiology. Moreover, neurological studies were recommended to gain a deeper understanding of the evolutionary origins and adaptive functions of voice modulation.
Expertise-dependent perceptual performance in chess tasks with varying complexity
Authors: Küchelmann Thomas , Velentzas Konstantinos , Essig Kai , Koester Dirk , Schack Thomas
Published: November 2022

Perceptual performance, anticipating opponents' strategies, and judging chess positions especially in subliminal processing is related to expertise level and dependent on chunking processes. It becomes obvious that chess expertise is a multidimensional phenomenon related predominantly to experience. Under consideration of chess expertise categorization, we conducted two priming experiments expanding existing designs by gradually increasing the target and task complexity. The main aim was the evaluation of potential visuocognitive limitations. The results reveal experts' perceptual superiority manifested by their faster reaction times in settings with increased stimulus and task complexity. Further, experts' priming effects seem to be affected by the target content and/ or priming duration. For short prime duration, experts show priming effects only for less complex prime-target content. Interestingly, for longer prime duration and more complex prime-target content, all participants reveal priming effects. In summary, we argue that experts' visuocognitive processing (i.e., detecting or anticipating potential threats to the king) is rooted in a more efficient visuocognition due to stored chunks of checking and mating constellations. We suggest that visuocognitive limitations are related also to the prime-target complexity as well as to the task. Further investigations must be conducted in order to elucidate the factors with an increased impact on chess players' performance.
Convolutional neural networks reveal differences in action units of facial expressions between face image databases developed in different countries
Authors: Inagaki Mikio , Ito Tatsuro , Shinozaki Takashi , Fujita Ichiro
Published: November 2022

Cultural similarities and differences in facial expressions have been a controversial issue in the field of facial communications. A key step in addressing the debate regarding the cultural dependency of emotional expression (and perception) is to characterize the visual features of specific facial expressions in individual cultures. Here we developed an image analysis framework for this purpose using convolutional neural networks (CNNs) that through training learned visual features critical for classification. We analyzed photographs of facial expressions derived from two databases, each developed in a different country (Sweden and Japan), in which corresponding emotion labels were available. While the CNNs reached high rates of correct results that were far above chance after training with each database, they showed many misclassifications when they analyzed faces from the database that was not used for training. These results suggest that facial features useful for classifying facial expressions differed between the databases. The selectivity of computational units in the CNNs to action units (AUs) of the face varied across the facial expressions. Importantly, the AU selectivity often differed drastically between the CNNs trained with the different databases. Similarity and dissimilarity of these tuning profiles partly explained the pattern of misclassifications, suggesting that the AUs are important for characterizing the facial features and differ between the two countries. The AU tuning profiles, especially those reduced by principal component analysis, are compact summaries useful for comparisons across different databases, and thus might advance our understanding of universality vs. specificity of facial expressions across cultures.
Exploring links between Chinese military recruits' psychological stress and coping style from the person-environment fit perspective: The chain mediating effect of self-efficacy and social support
Authors: Wu Chao , Hou Guangdong , Lin Yawei , Sa Zhen , Yan Jiaran , Zhang Xinyan , Liang Ying , Yang Kejian , Zhang Yuhai , Lang Hongjuan
Published: November 2022

The choice of coping style of recruits under psychological stress in the process of military task execution has been an important topic in the promotion of military operations and cohesion of military forces. Taking a positive coping style under psychological stress can help recruits overcome the negative effects of stress and improve military morale and group combat effectiveness. Although soldiers' psychological stress in the process of military mission execution having an impact on coping style has been studied by a large body of literature, very little literature has focused on the mechanism of self-efficacy and social support between recruits' psychological stress and coping style from the person-environment fit perspective. Therefore, this study was conducted to analyze the impact of recruits' psychological stress on coping style through a chain mediation model and to discuss the role of self-efficacy and social support in this relationship. Two waves of survey data were utilized to test the research hypotheses on a sample of 1028 Chinese recruits performing military tasks. The results indicated that recruits' psychological stress negatively impacted positive coping styles and positively correlated with negative ones. In addition, self-efficacy and social support mediated the relationship between psychological stress and positive coping style, and self-efficacy mediated the relationship between psychological stress and negative coping style. More importantly, self-efficacy and social support play the chain mediating effect between psychological stress and positive coping style.
Motor constellation theory: A model of infants’ phonological development
Authors: Ekström Axel G.
Published: November 2022

Every normally developing human infant solves the difficult problem of mapping their native-language phonology, but the neural mechanisms underpinning this behavior remain poorly understood. Here, motor constellation theory, an integrative neurophonological model, is presented, with the goal of explicating this issue. It is assumed that infants’ motor-auditory phonological mapping takes place through infants’ orosensory “reaching” for phonological elements observed in the language-specific ambient phonology,viareference to kinesthetic feedback from motor systems (e.g., articulators), and auditory feedback from resulting speech and speech-like sounds. Attempts are regulated by basal ganglion–cerebellar speech neural circuitry, and successful attempts at reproduction are enforced through dopaminergic signaling. Early in life, the pace of anatomical development constrains mapping such that complete language-specific phonological mapping is prohibited by infants’ undeveloped supralaryngeal vocal tract and undescended larynx; constraints gradually dissolve with age, enabling adult phonology. Where appropriate, reference is made to findings from animal and clinical models. Some implications for future modeling and simulation efforts, as well as clinical settings, are also discussed.
Effects of physical activity and sleep duration on fertility: A systematic review and meta-analysis based on prospective cohort studies
Authors: Zhao Fanqi , Hong Xiang , Wang Wei , Wu Jingying , Wang Bei
Published: November 2022

Objective

Subfertility is a common problem for couples in modern society. Many studies have confirmed that lifestyle factors can affect fertility although there are conflicting conclusions relating to the effects of physical activity and sleep duration on fertility. In this study, we aimed to summarize and analyze the available evidence.

Methods

PubMed, Web of Science, Cochrane, and Embase databases (as of October 14, 2022) were systematically searched for eligible prospective cohort studies. Data were extracted and effect values were combined. We also performed methodological quality and bias risk assessments for all the included studies.

Results

A total of 10 eligible articles were included in our analysis; seven investigated the relationship between physical activity and fertility, and three investigated the effect of sleep duration on fertility. Compared with the lowest level of physical activity, high intensity physical activity (the highest levels of physical activity) was negatively correlated with fertility [odds ratio (OR) = 0.84; 95% confidence interval (CI): 0.70, 1.00, I2 = 64%]. However, we did not find an association between moderate intensity physical activity and fertility (OR = 1.09; 95% CI: 0.98, 1.22, I2 = 60%). We observed an inverse association between limited sleep duration (≤ 7 h) and fertility (OR = 0.92; 95% CI: 0.84, 1.00, I2 = 0%) compared with 8 h of sleep. The relationship between long sleep duration (≥9 h) and fertility was not statistically significant (OR = 0.85; 95% CI: 0.60, 1.21, I2 = 83%). According to the Newcastle-Ottawa Scale score, the overall quality of the research articles included was ranked as medium to high (6–9). Through GRADE system, the quality of evidence for the impact of high intensity physical activity and limited sleep duration on fertility was moderate, while the quality of evidence for the impact of moderate intensity physical activity and long sleep duration on fertility was low.

Conclusion

The current evidence shows that high intensity physical activity and limited sleep time are negatively related to fertility. But there was great heterogeneity among studies, and the quality of research evidence was low to median. Thus, further high-quality research is needed to confirm this conclusion.

PROSPERO registration number

CRD42022298137.
Health conditions among farmworkers in the Southwest: An analysis of the National Agricultural Workers Survey
Authors: Soto Sheila , Yoder Aaron Meck , Nuño Tomas , Aceves Benjamin , Sepulveda Refugio , Rosales Cecilia Ballesteros
Published: November 2022

Agricultural jobs pose many challenges to the health and wellbeing of a disadvantaged population. In the Southwest region, the socioeconomic factors of living along the U.S.-Mexico border, migration patterns, lack of access to health care, low utilization of health care services, lack of health insurance, and highly demanding occupation may uniquely affect health outcomes for farmworkers. This paper presents descriptive information for professionals to improve access to care by tackling barriers afforded by the agricultural industry. The National Agricultural Worker Survey (NAWS) is an employment-based, random-sample survey of U.S. agricultural workers in six regions: East, Southeast, Midwest, Southwest, Northwest, and California. We examined farmworkers' self-reported health conditions, including asthma, diabetes, high blood pressure, other chronic conditions, or any condition by region from 2013 to 2016. We used logistic regression to determine differences in lifetime prevalence of health conditions between farmworkers in the Southwest region (n = 727) and farmworkers in other regions (n = 8,850) using weighted data. After adjusting for age, gender, income, insurance status, and English-speaking ability, the odds of high blood pressure and other condition were similar in all regions. The prevalence of diabetes was almost double in the Southwest (114.2 per 1,000 farmworkers). The odds of diabetes were 1.31 (95% CI 0.99, 1.74) times greater in the Southwest region than in the other regions. Asthma was the only condition that was lower in the Southwest (22 per 1,000 farmworkers) compared to the other regions. The odds of asthma were 0.61 (95% CI 0.36, 1.03) times lower in the Southwest region than in other regions. The results follow previous studies on the prevalence of asthma among the farmworker population and elevated probability of chronic diseases including diabetes among the Latino population in the U.S.
Effects of age and pasture type on the concentration and prevalence of tetracycline and macrolide resistant Enterococcus species in beef cow-calf production system
Authors: Agga Getahun E. , Galloway Hunter O. , Netthisinghe Annesly M. P.
Published: November 2022

Enterococci are a normal flora of the gastrointestinal tracts of humans and animals. Enterococci can also cause life-threatening nosocomial infections. Antimicrobial-resistant Enterococcus species have been reported in the feedlot and dairy cattle productions and in meat and milk products, suggesting their foodborne importance. Cow-calf operations represent a significant segment in the beef production system by producing weaned calves. Weaned calves are brought into the feedlot to be finished for meat, and culled cows are also slaughtered for beef, primarily for ground beef products. Infection dynamics in the cow-calf operation can contribute to meat contamination. This study evaluated the effects of age and wheat grazing on the concentration and prevalence of a macrolide antibiotic erythromycin (ERYr) and tetracycline (TETr) resistant enterococci, associated resistance genes and species distribution in a cow-calf production system. In 2017 and 2018, 32 Angus breed cow-calf pairs were randomly assigned to feed on tall fescue or wheat pasture in two independent field experiments. During the grazing experiments of 2-3 weeks, fecal samples were collected weekly and cultured to enumerate, isolate and identify ERYr, TETr, and generic enterococci, using media supplemented with erythromycin, tetracycline or non-supplemented media, respectively. The two main species frequently associated with human illnesses, Enterococcus faecium and E. faecalis, were widely distributed in the cow-calf groups. Generic and TETr- enterococci were prevalent (96-100% prevalence) and abundant (3.2-4.9 log10 CFU/g) in the cow-calf population; however, ERYr enterococci were enumerable by direct plating only from a single cow despite being detected in at least 40% of the fecal samples after enrichment, showing their low abundance. TET- and ERY-resistance were mainly conferred by tet(M) and erm(B), respectively. Wheat grazing reduced the concentration of TETr enterococci and modified enterococcal species and resistance gene distributions. Hence, it is necessary to further investigate wheat grazing in cow-calf production as a potential strategy to mitigate antimicrobial resistance.
Effects of 5-alpha reductase inhibitors prior to Holmium Laser Enucleation of the prostate: Does increased adenoma density result in prolonged morcellation times?
Authors: Ganesh Meera B. , Lee Matthew S. , Han Joshua G. , Assmus Mark A. , Dean Nicholas , Helon Jessica W. , Krambeck Amy E.
Published: November 2022

Introduction

The use of 5-alpha reductase inhibitors (5-ARIs) has been shown to improve lower urinary tract symptoms (LUTS) and decrease prostate size in men with benign prostate hyperplasia (BPH). 5-ARI therapy could increase prostate tissue density through increased collagen deposition and contraction of stromal/epithelial components. Increased tissue density could prolong morcellation times, but the effects of preoperative 5-ARI exposure on morcellation efficiency during Holmium Laser Enucleation of the Prostate (HoLEP) are not well described. Herein, we examine outcomes after HoLEP of patients on pre-operative 5-ARIs.

Methods

A retrospective review of patients undergoing HoLEP by an expert surgeon from Jan – Oct 2021 was performed. Student t-tests and chi-square tests were performed for continuous and categorical variables, respectively. Matched-pair analysis was performed using SPSS v28 (IBM, 2022). A p-value <0.05 was determined statistically significant. All other statistical analyses were performed using SAS v9.4 (SAS, 2019).

Results

A total of 322 patients underwent HoLEP during the study period and 84 patients had pre-operative 5-ARI exposure. Patients in the 5-ARI group had larger preoperative prostate size (p = 0.016). Morcellation time was longer (p=0.01), specimen weight was higher (p=0.02), and morcellation efficiency (p=0.02) was lower in the 5-ARI group. After matching, there were 67 patients in each chort (total 134) and these associations for size, morcellation time, specimen weight, and morcellation efficiency were no longer seen (p=0.8, 0.6, 0.5, and 0.7, respectively). Furthermore, no associations between 5-ARI and post-operative admissions or ED visits were noted.

Conclusion

In this retrospective study, preoperative use of 5-ARIs did not affect enucleation or morcellation efficiency. Thus, preoperative 5-ARI therapy does not appear to alter outcomes after HoLEP.
A conceptual analysis of maltreatment in sports: A sport social work perspective
Authors: Gattis Courtney , Moore Matt
Published: November 2022

Maltreatment in sports is an epidemic and occurs in many relational forms such as physical, sexual, and emotional abuse or neglect. Maltreatment in sports also exists in forms of non-relational abuse and focuses on mezzo and macro forms of maltreatment such as systematic abuse, organizational abuse, and physiological abuse or neglect (e.g., exploitation and athlete trafficking). It is imperative to study the effects of maltreatment in sports as athletes can be the victims (survivors) as well as perpetrators of abuse. Recent research in the field of social work points to the benefits of Trauma-Informed Sports and Short Focused Brief Therapy (SFBT) as possible interventions. It is imperative for transferability in the field of maltreatment in sports, that practitioners define each form of abuse in the context of maltreatment and trauma. This commentary aims to discuss the different forms of maltreatment in sports that could affect athletes and provide discussion and insights into the void of research surrounding certain forms of non-relational abuse and the role trauma-informed therapies serve in promoting athlete wellbeing from a social work lens.
Soils and olericultural practices in circumpolar region of Russia at present and in the past
Authors: Nizamutdinov Timur , Suleymanov Azamat , Morgun Evgeniya , Yakkonen Kirill , Abakumov Evgeny
Published: November 2022

Circumpolar regions are often associated with activities such as reindeer herding, hunting, fishing, and gathering wild foods, but few know that locals have practiced olericulture since ancient times. Under a changing climate, the agricultural frontier will inevitably shift northward, so it is important to understand the current and past patterns of local soil functioning. Olericultural practices in the Arctic region seem difficult due to the harsh climate; however, it is being implemented. In this paper, we report the agricultural practices used by local residents to increase the yield of crops grown in the Yamal region. We also studied the chemical properties and fertility of soils under private gardens (both active and abandoned). At present, the yields of private olericulture in Yamal even exceed those of industrial vegetable-growing farms. It is revealed that private vegetable growers can achieve an increase in soil fertility by increasing the content of nutrients (P2O5 over 1,500 mg kg−1, K2O up to 500 mg kg−1) and organic carbon up to 17%, as well as the regulation of the acid-alkaline regime. It is also found that soil fertility indicators in private vegetable gardens are higher compared to industrial fields. Such soils are not typical for the cryolithozone and can be classified as Anthrosols. Soils of abandoned vegetable gardens can retain a high level of fertility for a long time due to the specific climatic conditions of the Arctic. As a result, the research showed that it is possible to grow vegetables beyond the Arctic Circle by adapting local soils and applying specific practices typical for cryolithozone.
Potential of traditional Chilean blood-fleshed peach to support livelihood opportunities in local agriculture
Authors: Marchant Lorena , Campos Javiera , Luco Javiera , Ramirez Cesar , Barrientos Freddy , Carrasco Basilio , Silva Herman
Published: November 2022

The blood-flesh peach or vineyard peach is an older heritage cultivar with juicy red-flesh and tart-sweet flavor. They are popular in France, where more than 200 years ago wine growers used to plant them on the vineyards as biological markers to detect the presence of powdery mildew. It is present in countries such as China, Italy, New Zealand, Australia and USA however, it remains a very rare variety worldwide. In Chile, the blood-flesh peach has a centenary presence in rural orchards where is called “Durazno Betarraga.” Reproduced by seeds, it has pass through generations of family farmers and has been adapted to local environmental conditions. This red-flesh peach is a local variety considered part of their traditional diets, however, cultural changes in food consumption, short postharvest life and water scarcity due to climate change are threatening its conservation. One of the objectives of the International Year of Fruits and Vegetables, as defined by the FAO, is to integrate small holders and family farmers into value chains for sustainable production and consumption of fruits and vegetables recognizing the contributions of farmer's landraces to their food security, nutrition, livelihoods and income. To promote this objective, we present the work we have been carry out for several years with a farming community. We have conducted ethnographic research to provide a qualitative description of the agricultural value of the blood peach in a limited territory of the Maule Region defined as the study area. For the quantitative section of our research we analyzed the antioxidant capacity (ORAC) and total polyphenol content and compared them with those of other fruits. To gather information on the presence of the blood-fleshed peach in other regions of Chile, we used a citizen science approach through social networks. We propose that this local variety is an innovative raw material to develop healthy fruit-based food, thus encouraging its conservation and consumption with a positive social and economic impact for the community and the local food system.
Dietary habits during the COVID-19 pandemic. Are work environments part of the problem?
Authors: Tiboni-Oschilewski Ornella , Perez-Silva Rodrigo , Biasini Beatrice , Scazzina Francesca
Published: November 2022

The COVID-19 pandemic pushed a large number of workers out of their offices and to their homes for a significant period of time for teleworking. However, some workers continued to work in their offices and others went home only partially. This arguably exogenous shock to the way in which workers performed their jobs opened the opportunity to evaluate whether work environments are ideal for promoting healthier diets and reducing overweight among office workers. We explore the results of two consecutive surveys (pre- and during-COVID-19) to examine whether workers working from home perceived their situation as more favorable in terms of healthy eating habits and weight gains. Our results show that workers did perceive their homes as places where they can follow healthier eating habits, but this was not accompanied by weight loss. On the contrary, workers fully teleworking were more likely to perceive weight gains and diet-related health problems than their in-office counterparts. Among teleworkers, those only partially teleworking were the most affected. This study opens many questions about food environments at work that remain unanswered. More studies in this area are needed to understand how the food at work affects the worker's health.