bluuebunny/crossref_metadata_2025 huggingface dataset:
Nonrefrigerated Dry Storage Can Have Negative Effects on Postharvest Quality of Cut Lilium
Authors: Chen Yen-Hua , Miller William B.
Published: October 2022

Water uptake is a critical issue for postharvest physiology of cut flowers. After harvest, cut flowers lose access to water from roots and sometimes develop emboli inside the xylem, which can disrupt water uptake and undermine flower longevity. The duration of dry storage (desiccation) before flowers are placed in a vase may affect rehydration capability. Despite the appreciated importance of desiccation time on water balance, the duration of desiccation that might cause irreversible damage in Lilium sp. L. is unknown. Therefore, we investigated effects of pre-vase dehydration on water uptake and postharvest quality of cut lilies. Stems of Lilium ‘Nashville’, ‘Santander’, and ‘Sorbonne’ were subjected to 0, 8, 24, or 48 hours of dehydration at 20 °C, then rehydrated in a solution containing 2% sucrose and a biocide. Water uptake in the first 24 hours of rehydration was significantly greater in dehydrated stems than in control (0 hour) stems. Although dehydration treatments increased water uptake in the first 24 hours after rehydration, total water uptake in dehydrated stems over the ensuing 9- to 10-day vase period was significantly less than in controls. In the vase, 48 hours of dehydration reduced the total water uptake in ‘Nashville’ by 27% and in ‘Sorbonne’ by 48%. Individual flower life and stem vase life were not affected significantly by dehydration treatment; however, ‘Sorbonne’ stems dehydrated for 24 or 48 hours had smaller flowers than controls and those that underwent the 8-hour dehydration treatment. ‘Nashville’ stems dehydrated for 24 hours showed visible leaf yellowing 3 days earlier than controls; ‘Sorbonne’ dehydrated for 48 hours showed leaf yellowing 2 days earlier. We conclude cut lilies have an ability to recover partially from significant dehydration and can restore water uptake initially, but pre-vase dehydration reduces total water uptake and affects some postharvest attributes negatively.
A Systematic Literature Review on the Relationship Between Positive Psychological Capital and Work engagement: Focusing on Korean Journal Articles
Authors:   Human Engagement Institute, Jeon Hyeji , Jo Hyunjeong , Kim Woocheol
Published: October 2022

This study presents implications and future research directions by analyzing the relationship between positive psychological capital and work commitment in Korea and analyzing the relationship between two variables as well as the relationship between two sub-factors, preceding variables, result variables, mediating variables, and moderating variables. The most significant results of analyzing the sub-factors of 53 KCI-listed journal articles that studied the relationship between the two variables are as follows: First, the number of studies on the relationship between positive psychological capital and work commitment has been increasing since 2012, and most of them involved corporate employees and service workers in the fields of management and tourism. Second, when analyzing the relationship between positive psychological capital and work commitment with the relationship between sub-factors controlled, some studies have yielded inconsistent results according to the meanings and structures of the sub-factors. Third, the preceding/mediated/modulated/result variables related to the relationship between the two variables were classified based on the job demand-resource (JD-R) model, and a conceptual integrated model was employed. This study presents its implications and future research directions based on the results.
The origin of Herbaceous hybrid Group peony cultivars of the M. M. Gryshko National Botanical Garden of NAS of Ukraine collection and the prospects for their use
Authors: Gorobets V. F. , Shcherbakova T. O.
Published: October 2022

Purpose. To analyze the origin of the Herbaceous Hybrid Group peony cultivar collection of the M. M. Gryshko National Botanical Garden (NBG) National Academy of Sciences of Ukraine (NAS) and to determine the prospects for their use in breeeding work and decorative horticulture.
Methods. The object of research was peonies of the Herbaceous Hybrid Gp of the NBG peony collection. The plants are grown on sunny open experimental and exposition plots of the NBG. Cultivars studies and phenological observations of plants were carried out during 2012–2022.
Results. Varietal diversity of Herbaceous Hybrid Gp peonies of the NBG collection was analyzed by origin. The analysis showed that 122 varieties were created by US breeders, of which the Saunders breeding is represented by the largest number of varieties in the collection. 38 varieties are of Ukrainian breeding and created in the NBG. The analysis of hybrids obtained by distant crosses made it possible to identify combinations that give fertile offspring and to create promising double and triple hybrids. For decorative horticulture, 165 varieties of world and domestic breeding are recommended. They were grouped into four groups by flower color and two groups by the beginning of flowering. Plants of the early group start flowering before May 22 (± 4 days). The flowering of the late group of varieties occurs at the beginning of the flowering of the variety ‘Red Charm’ (May 22 ± 4 days) and later.
Conclusions. For more than 50 years of introductory work with peony Herbaceous Hybrid Gp, 133 varieties of world breeding were tested at NBG. The main number of varieties was included in the collection in the first years of the 21st century. A comparative study of new varieties showed that most of them are sterile. Varieties ‘Dreamtime’, ‘Greenland’, ‘Quitzin’, ‘Lavender Whisper’, ‘Lemon Chiffon’, ‘Pastelegance’, ‘Pastelorama’, ‘Salmon Dream’, ‘Sunny Boy’, ‘Sunny Girl’, ‘Sunny Day’, ‘The Mackinac Grand’, ‘Vanilla Schnapps’, ‘Triphena Parkin’, ‘Pink Vanguard’, ‘Lavender Whisper’, were fertile and can be successfully used in the hybridization process. It was revealed that the source of early flowering of varieties created in the NBG was introduced wild species of herbaceous peonies: P. peregrina, P. wittmanniana, P. arietina. Peonies with double or semi-double flowers can be obtained by using P. officinalis ‘Rubra Plena’ with double flowers as a maternal component, and P. lactiflora varieties (‘President Taft’, ‘La Pionce’, ‘Lord Kitchener’, ‘Adolphe Roussean’, ‘M-lle Janne Riviere’) as paternal one also with terry flowers
Efficiency of using of wheat-rye translocations (WRT) 1AL/1RS and 1BL/1RS in soft winter wheat breeding
Authors: Lytvynenko M. A. , Holub E. A. , Khomenko T. M.
Published: October 2022

Purpose. To determine the genetic effects of WRT 1AL.1RS and 1BL.1RS on the yield, plant productivity elements and quality indices of recombinant lines, to determine the effectiveness of using each of the WRT for creating more perfect varieties of soft winter wheat in these traits under soil-air drought in the steppe zone of Ukraine and development of breeding techniques to reduce the negative effects of translocation to produce genotypes with high quality indices of valuable and strong wheat grain.
Methods. Field experiments, intraspecific hybridization, evaluation of breeding material in the field, methods of laboratory determination of baking quality indices of grain, electrophoresis of spare proteins, statistical.
Results. Under arid conditions of the South of Ukraine on the large experimental material of breeding process, a positive effect of 1AL.1RS on the yield of recombinant lines and the main elements of plant productivity were determined, which was manifested against the background of simultaneous positive effect of this transposition on the drought and heat tolerance. The use of 1BL.1RS in wheat breeding in this region is less promising technique. It has been determined that introduction of 1AL.1RS, 1BL.1RS translocations into local gene pool of soft winter wheat by hybridization changes the grain quality indices. In particular, the protein content tends to increase more significantly under the influence of 1BL.1RS translocation. It has been shown that the frequency of obtaining recombinant lines which combine high yield and sufficient level of baking properties (not lower than valuable and strong wheat) is quite low (1,7–6,1%), but introgressive lines with 1AL.1RS have the advantages in this parameter. Using such genetic factors as hybridization combining WRT with alleles with high positive effect on baking properties, and also creating heterogeneity in the composition of genotypes with and without WRT, one can purposefully reduce the negative impact of WRT on the quality of soft winter wheat grain and create varieties with quality parameters of valuable and strong wheat.
Conclusions. In general, the results achieved give reason to assert that the use of WRT 1AL.1RS is a promising direction for further breeding increase of genetic capacity of soft winter wheat varieties in the arid conditions of the South of Ukraine. As a result of full cycle of breeding process on the material with 1AL.1RS WRT a series of varieties of soft winter wheat ‘Zhytnytsia odeska’, ‘Oktava odeska’, ‘Liha odeska’, ‘Duma odeska’, ‘Versiia odeska’, providing 10 – 15% increase in yield to standards was created and included in the State Register of Ukraine and Moldova.
Introduced and registered switchgrass varieties (Panicum virgatum L.) as a source material for breeding for biomass productivity
Authors: Kulyk M. I. , Rozhko I. I.
Published: October 2022

Purpose. On the basis of multi-year research on the complex of economically valuable characteristics, the best switchgrass varieties (Panicum virgatum L.) ‘Patfinder’, ‘Carthage’, ‘Blackwell’, ‘Morozko’, ‘Liadovske’ and ‘Zoriane’ were singled out as a source material for breeding for productivity.
Methods. The research was conducted during 2017–2021 on the basis of the Poltava State Agrarian University. The soils of the experimental site of the “Energy Crops” collection are typical chernozems with a humus content of 3.4%. Plots were planted with randomized placement of options in four-fold repetition according to the methods of experimental work in agronomy. Also, approved scientific-practical and methodical recommendations for growing energy crops were applied. To confirm the significant difference between the studied varieties, dispersion analysis using Excel and Statistica programs was used.
Results. Switchgrass varieties were grouped according to the duration of the growing season into: early- (up to 160 days), medium- (161–171 days) and late ripening (more than 170 days). The complex resistance of switchgrass varieties to drought, frost and plant lodging: ‘Cave-in-Rock’, ‘Zoriane’, ‘Morozko’ and ‘Liadovske’ was revealed. It was determined that economically valuable characteristics depend to a greater extent on varietal characteristics than on growing conditions. The yield of ground vegetative mass based on dry residue for the studied varie­ties varied from 12.1 to 15.6 t/ha.
Сonclusions. The varieties ‘Cave-in-Rock’, ‘Zoriane’, ‘Morozko’, ‘Liadovske’ were the most adaptable to growing conditions. The switchgrass varieties ‘Kanlow’ and ‘Cave-in-rock’ provided the highest plant stand and switchgrass variety ‘Dacotah’ provided the lowest plant stand. Varieties ‘Pathfinder’, ‘Blackwell’, ‘Shelter’, ‘Carthage’ and ‘Zoriane’ were singled out according to the number of stems and productivity. The latter, together with the Ukrainian variety ‘Zoriane’, are recommended to be used as starting material for crop selection based on biomass productivity.
Ética de la tecnociencia
Authors: Mendieta Lemin
Published: October 2022

Nos acercamos a la tecnociencia desde uno de los espacios más discutidos en la actualidad, cuál es el de la ética como disciplina que estudia el comportamiento moral de quienes investigan en el campo de la tecnociencia. El objetivo es aproximarnos a los fundamentos filosóficos y científicos para presentar una postura que cribe las relaciones existentes entre ciencia-filosofía-técnica y ética y, analizar las implicaciones de la tecnociencia en la ética. Realizamos revisiones a los planteamientos de algunos filósofos para entramar la ética con la tecnociencia y está con el hombre como ser vital. Concluimos que la filosofía tiene como tarea necesaria vital el reflexionar, criticar y presentar sus posturas ante el desarrollo de la tecnociencia como nueva forma de construir el mundo, que debe estar alerta ante los embates de esta y delimitar desde el campo de la ética aquellos caminos que deben seguir los tecno científicos, así también, que el ser humano es mente y cuerpo, que es y será vida y la máquina por más inteligente que sea, es y será máquina.
Adiciones a la flora arbórea de Ayacucho: La Mar, Distrito Oronccoy, San Martin de Chupón - Belén Chapí (VRAEM)
Authors: Suclli Efrain , Vargas Luis , Ventura Richar , Huaranccay Jhoel
Published: October 2022

Se da a conocer 30 nuevas adiciones de plantas vasculares de porte arbóreo a la Flora de Ayacucho, emplazados en el bosque montano oriental y el límite superior del bosque tropical estacional seco del río Apurímac, comprendido entre las localidades de San Martin de Chupón y Belén Chapí, del distrito de Oronccoy, provincia de La Mar, región Ayacucho. Esta contribución al conocimiento de la flora regional, es el resultado del trabajo de campo y de herbario tras dos campañas exploratorias en un territorio inhóspito y vacío en información biológica. Considerando que a la fecha se tienen documentadas 1070 especies de flora vascular para la región (Brako & Zarucchi, 1993), los taxones reportados se presentan en la categoría de nuevos registros y una posible nueva especie perteneciente al género Cereus.
Security for Multi-hop Communication of Two-tier Wireless Networks with Different Trust Degrees
Authors: Thai Chan , Bao Vo Nguyen Quoc , Thai Uyen Han Thuy
Published: October 2022

Many effective strategies for enhancing network performance have been put forth for wireless communications’ physical-layer security. Up until now, wireless communications security and privacy have been optimized based on a set assumption on the reliability or network tiers of certain wireless nodes. Eavesdroppers, unreliable relays, and trustworthy cooperative nodes are just a few examples of the various sorts of nodes that are frequently categorized. When working or sharing information for one another, wireless nodes in various networks may not always have perfect trust in one another. Modern wireless networks’ security and privacy may be enhanced in large part by optimizing the network based on trust levels. To determine the path with the shortest total transmission time between the source and the destination while still ensuring that the private messages are not routed through the untrusted network tier, we put forth a novel approach. Toexamine the effects of the transmit SNR, node density, and the percentage of the illegitimate nodes on various network performance components, simulation results are provided.
Assessing wastewater pollution from outdoor night markets and its impacts on river quality
Authors: Kang Shyh-Fang , Lin Jen-Yang , Chong Kean-Yip , Lin Yu-Tse , Chen Chi-Feng
Published: October 2022

Night markets are attractive tourist sites in Asian cities. However, the outdoor activities produce different types of pollutants. Air pollution and solid waste in night markets have received much attention, but wastewater pollution from night markets has rarely been examined. The untreated wastewater are discharged into roadside gutters and might contaminate receiving waterbodies. In this study, night markets in Taipei city, Taiwan, were surveyed to clarify the characteristics of wastewater. The sampled wastewater showed high levels of organic substances, oil and grease, and phosphorous but low levels of nitrogen compounds. In addition, the unit pollution loads in night market stalls were obtained. The BOD load of each stall in the night markets was 2,509 g/day, which is higher than the sewage emissions of 50 people. In order to know the impacts of night market wastewater on the receiving waterbody, a water quality model, the Water Quality Analysis Simulation Program (WASP), was used in the studied river, Keelung River. If night market wastewater could be collected (not discharged), the BOD concentration could be reduced by 9.8%, but the NH3-N and DO concentration could be reduced by less than 1%.
Lactoferrin: An Effective Weapon in the Battle Against Bacterial Infections
Authors: Avalos-Gómez Christian , Ramírez-Rico Gerardo , Ruiz-Mazón Lucero , Sicairos Nidia León , Serrano-Luna Jesús , de la Garza Mireya
Published: October 2022

The emergence of multidrug-resistant bacterial strains with respect to commercially available antimicrobial drugs has marked a watershed in treatment therapies to fight pathogens and has stimulated research on alternative remedies. Proteins of the innate immune system of mammals have been highlighted as potentially yielding possible treatment options for infections. Lactoferrin (Lf) is one of these proteins; interestingly, no resistance to it has been found. Lf is a conserved cationic nonheme glycoprotein that is abundant in milk and is also present in low quantities in mucosal secretions. Moreover, Lf is produced and secreted by the secondary granules of neutrophils at infection sites. Lf is a molecule of approximately 80 kDa that displays multiple functions, such as antimicrobial, anti-viral, anti-inflammatory, and anticancer actions. Lf can synergize with antibiotics, increasing its potency against bacteria. Lactoferricins (Lfcins) are peptides resulting from the N-terminal end of Lf by proteolytic cleavage with pepsin. They exhibit several anti-bacterial effects similar to those of the parental glycoprotein. Synthetic analog peptides exhibiting potent antimicrobial properties have been designed. The aim of this review is to update understanding of the structure and effects of Lf and Lfcins as anti-bacterial compounds, focusing on the mechanisms of action in bacteria and the use of Lf in treatment of infections in patients, including those studies where no significant differences were found. Lf could be an excellent option for prevention and treatment of bacterial diseases, mainly in combined therapies with antibiotics or other antimicrobials.
Bone Marrow Stromal Stem Cell Fate Decision: A Potential
Mechanism For Bone Marrow Adipose Increase with Aging-related
Osteoporosis
Authors: Tian Li , Lu Lingyun , Meng Yang
Published: October 2022

Objective:

Osteoporosis is a systemic bone disease that seriously threatens
the health and quality of life in middle-aged and older adults. In this review, we
describe the relationship between bone marrow adipose tissue and aging osteoporosis
and mainly focus on bone marrow mesenchymal stem cell osteogenic-adipose differentiation
fate with aging along with the relevant mechanisms responsible for these
changes.

Methods:

We summarized recent advances in regulating the bone marrow mesenchymal
stem cell differentiation due to aging in this review.

Results:

Aging-related bone mass loss is accompanied by expanding bone marrow
adipose because of an imbalance of bone marrow mesenchymal stem cell differentiation,
resulting in adipogenesis. Ectopic adipocytes in the bone marrow increase with
age and are a key factor responsible for the aging-related bone mass decrease.
Transcription factors and classical regulating pathways are involved in this process
during aging.

Conclusion:

As the global aging population increases, not only older women but also
older men face a great fracture risk. Therefore, finding molecular mechanisms controlling
the stimulating adipogenesis in BMSC during aging is important for providing the
new cue for prevention and therapeutics for aging-related bone loss. Furthermore,
upon physical examination of older people, except for the bone mineral density and
bone turnover biochemical marker, the bone marrow adipose measurement should be
taken into account when assessing the fracture risk and treatment plan that will be
beneficial in clinical practice.
Cerebrospinal Fluid CSF Flow Artifacts are Associated with Brain
Pulsation in Patients with Severe Carotid Artery Stenoses
Authors: Imaizumi Toshio , Nomura Tatsufumi , Komura Shoichi , Inamura Shigeru , Tamada Tomoaki , Kanno Aya , Nonaka Tadashi
Published: October 2022

Objective:

We investigated the factors associated with cerebrospinal fluid (CSF) flow
artifacts on fluid-attenuated inversion recovery imaging in patients with carotid artery (CA) stenosis.

Methods:

Each CSF artifact grade was defined by comparing the highest intensity in a given region
of interest (ROI) to those in reference ROIs, as follows: higher than the intensity of normal white
matter in the centrum semiovale = 2 points; equal to or less than the white matter, and higher than
CSF = 1 point; and equal to CSF = 0. CSF flow scores in eight sites were measured and added to the
total score (0 -16). The prevalences of each finding, specifically white matter lesions, CA stenoses
and brain atrophy, were compared using multivariate logistic regression models.

Results:

We evaluated the findings in 54 patients with CA stenosis treated by CA stenting (CAS)
and 200 adults with no history of neurological disorders (control group). Adjusted by stroke risk
factors, a CSF flow score ≤ 11 was positively associated with CA stenosis, heart rate > 70 / min, and
brain atrophy, and negatively with the female gender. The score was 12.8 ± 1.8 in the control group
and 12.0 ± 2.0 in CA stenosis group after CAS, which was significantly higher than before CAS
(10.4 ± 2.8, p<0.001).

Conclusions:

The CSF flow score was associated with female gender, brain atrophy, heart rate, and
severe CA stenosis, and was found to be elevated after revascularization.
Electro-acupuncture Promotes Angiogenesis via Exosomal miR-210 in the
Hypoxia-induced HUVECs Mediated HIF-1α/VEGF/Notch 1 Signal Pathway
Authors: Peng Yong-Jun , Xu Shu-Ying , Ni Si-Ming , Zeng Chun-Li
Published: October 2022

Background:

Acupuncture has been wildly applied for cerebral ischemia treatment in
China for thousands of years, while the specific mechanism remains uncertain. Recently, many studies
have shown that acupuncture promotes angiogenesis after ischemia occurs. Here, we examined
the effect of electro-acupuncture (EA) exosomes on angiogenesis in hypoxia-induced human umbilical
vein endothelial cells (HUVECs).

Objective:

To investigate whether EA exosomal miR-210 promotes angiogenesis in the hypoxiainduced
HUVECs via the HIF-1α/VEGF/Notch 1 signal pathway.

Methods:

The middle cerebral artery occlusion (MCAO) model was established and treated with EA
therapy. Then, exosomes were identified and isolated from rats' plasma in the MCAO+EA group by
transmission electron microscopy (TEM), surface markers expressions, and PKH26 reagent. MiR-
210 mimic, miR-210 inhibitor, and HIF-1α were transfected. Flow cytometry, CCK-8 assay, and
Transwell assay were conducted to assess the migration, apoptosis, and proliferation of each group
of cells. Western blot and quantitative PCR were performed to detect the CD34, HIF-1α, VEGF,
Notch 1, and miR-210 expression levels in each group.

Results:

MiR-210 was significantly upregulated in exosomes of the MCAO plasma, and further
enhanced by EA therapy. EA-EXOs and miR-210 mimic inhibited cell apoptosis, promoted cell
proliferation and cell migration in hypoxia-induced HUVECs. However, the miR-210 inhibitor reversed
the proliferation and migration number induced by EA-EXOs. Besides, EA-EXOs and miR-
210 mimic further enhanced those HIF-1α, VEGF, and Notch 1 levels compared to the hypoxia
treatment only. Silencing HIF-1α or miR-210 reversed the high expressions of those three angiogenic
factors induced by hypoxia and EA-EXO. qPCR showed similar trends with their relative
mRNAs. To analyze these associations quantificationally, Spearman's rank correlation coefficient
was calculated. As revealed by results, the expression of proteins and mRNA were highly correlative
with each other.

Conclusions:

These results indicated that EA-EXO miR-210 promotes angiogenesis in hypoxia conditions
via HIF-1α/VEGF/Notch 1 signal pathway.
Polyphyllin VII as a Potential Drug for Targeting Stemness in Hepatocellular Cancer via STAT3 Signaling
Authors: Li Fangzhou , Xi Xueyan , Xu Liuhang , Chen Ziqi , Wang Yangbin , Li Yulin , Wang Zhongyu
Published: October 2022

Background:

At present, the treatment of hepatocellular carcinoma (HCC) is disturbed by the treatment failure and recurrence caused by the residual liver cancer stem cells (CSCs). Therefore, drugs targeting HCC CSCs should be able to effectively eliminate HCC and prevent its recurrence. In this study, we demonstrated the effect of Polyphyllin VII (PP7) to HCC CSCs, and explored their potential mechanism.

Methods:

HepG2 and Huh7 cells, were used to analyze the antitumor activity of PP7 by quantifying cell growth and metastasis as well as to study the effect on stemness.

Results:

Our results demonstrated that PP7 promoted apoptosis and significantly inhibited proliferation and migration of both HepG2 and Huh7 cells. PP7 also inhibited tumor spheroid formation and induced significant changes in the expression of stemness markers (CD133 and OCT-4). These effects of PP7 were mediated by the STAT3 signaling.

Conclusion:

PP7 can effectively suppress tumor initiation, growth, metastasis, and inhibit stemness through regulation of STAT3 signaling pathway in liver cancer cells. Our data would add more evidence to further clarify the therapeutic effect of PP7 against HCC.
Overexpression of Bromodomain and Extraterminal Domain is Associated with
Progression, Metastasis and Unfavorable Outcomes: Highlighting Prognostic and
Therapeutic Value of the BET Protein Family in Gastric Cancer
Authors: Ghaffari Seyed H. , Fard Shahrzad S. , Kouchaki Shaghayegh , Salimian Zahra , Sotoudeh Masoud , Mousavi Seyed A. , Alimoghaddam Kamran
Published: October 2022

Background:

As epigenetic readers, Bromodomain and extraterminal domain (BET) proteins have attracted
immense interest in developing novel therapies targeting this family to inhibit cancer progression. Although the impact
of BRD4 in the carcinogenesis of various tumors has been widely investigated, little is known about the potential roles
of the BET family in gastric cancer.

Methods:

In this cohort study, we have screened the expression profile of the BET protein family, including three
members, BRD2, BRD3 and BRD4, in fresh gastric cancer (GC), adjacent non-tumor and normal gastric tissues, as
well as the anti-cancer effects and molecular mechanisms of BET inhibition in GC cell lines.

Results:

Among GC patients, BRD2, BRD3 and BRD4 showed overexpression, 48.07% (25/52), 61.5% (32/52) and
63.46% (33/52), respectively. The overexpression of BRD3 and BRD4 were remarkably associated with unfavorable
outcomes (HR = 2.023, P = 0.038; HR = 3.874, P = 0.001, respectively). However, multivariate Cox regression analysis
indicated that BRDs mRNA expression could not be used as an independent prognostic factor for GC patients after
adjustment with other variables. I-BET151, a potent pan-inhibitor, suppressing the BET family, decreased cell growth,
migration and invasion of GC cells. Interestingly, I-BET151 induced G1 cell cycle arrest through down-regulation of
c-Myc and its target, CDK2/Cyclin D1 complex.

Conclusions:

Our data provide insights into the prognostic role of the BET family in GC and proposed BET inhibition
as a therapeutic strategy for GC patients.
Technology transfer method of Tantri Darmaswami dance theater as a virtual work
Authors: Suteja I Ketut , Mawan I Gede
Published: October 2022

The COVID-19 pandemic has become a scourge for performing arts activists. The impact narrows the movement of art life, both formal and non-formal. Creative people try to be creative in finding breakthroughs to overcome this stagnation. This cannot be done unilaterally, it needs cooperation with the Business World and the Industrial World (DUDI) to communicate the results of the work. Solving problem, through the Diktiristek Matching Fund Program, the Faculty of Performing Arts (FSP) of the Indonesian Arts Institute (ISI) Denpasar in collaboration with PT. Bali Ranadha Television, created the work of Darmaswami Tantri Dance Theatre, which combines elements of tantri dance theater with cinematographic techniques into a virtual masterpiece. Using the technology transfer method is the transfer of the ability to utilize, master science, and technology. The goal is to increase art knowledge, produce quality creations, continue artistic work, and can be enjoyed by the public through virtual communication
Adsorbent technology platform for pretreatment of Biofuels
Authors:   Imerys, Williams Neal , Gittins David ,   Imerys, Smith Tony ,   Imerys
Published: October 2022

This presentation goes into detail on the types of filter aids; bleaching earth, silica gel, etc. and mechanisms such as adsorption, chelation, and hydration and the latest developments for optimal impurity removal for biorefineries.
Filter Media Options in Renewable Fuels and Edible Oils
Authors:   Dicalite Management Group, Inc., Galberd Zachary , Appelbaum Eric ,   Dicalite Management Group, Inc.
Published: October 2022

With the additional capacity being brought on in the biofuel space, additional filter media options must be considered. Adding capacity to the North American Diatomaceous Earth (DE) marketplace is a challenge but perlite and cellulose are viable alternatives. Both Biodiesel and Renewable Diesel are derived from fats and oils. These fats and oils can often present processing challenges due to contaminants that interfere with the efficiency of the reaction which need to be treated with adsorbent clays to protect catalyst activity. The use of DE, perlite or cellulose will improve the performance of the leaf filters, which also improves the performance of safety and polish filters. DE is the most well-known filter aid in this space, the use of perlite and cellulose offers many strategic benefits. Perlite offers greater efficiencies and economies than DE when used as a precoat for the treatment of fats and oils. Cellulose although not the most economical option, offers additional benefits that can counter its higher cost. This presentation looks at perlite and cellulose as alternatives to DE and highlight the benefits of each of them.
Pengaruh Frekuensi Penyiangan Gulma dan Jenis Pupuk Terhadap Hasil Tanaman Buncis Tegak (Phaseolus vulgaris L)
Authors: Subakti Harun , Wijaksono Karuniawan Puji
Published: October 2022

Tumbuhan invasif adalah semua jenis tumbuhan yang telah menyebar ke dalam suatu komunitas dan menyebabkan gangguan terhadap jenis tumbuhan lain. Studi mengenai spesies yang diintroduksi atau spesies yang berasal dari luar belum banyak dilakukan di Indonesia. Studi mengenai pengaruh lingkungan terhadap salah satu jenis asing invasif paling berbahaya yaitu Chromolaena odorata pun masih minim sehingga diperlukan adanya penelitian terkait hal tersebut. Penelitian ini dilaksanakan di lahan percobaan Jatimulyo, Lowokwaru, Kota Malang. Percobaan menggunakan Rancangan Acak Kelompok 1 faktor, yaitu intensitas naungan. Taraf naungan meliputi tanpa naungan/0% naungan (S1), naungan 50% (S2), naungan 70% (S3), dan naungan 90% (S4). Diulang sebanyak 6 kali, sehingga total unit percobaan sebanyak 24 unit. Metode pengambilan sampel berupa metode destruktif. Analisis Ragam menggunakan ANOVA dengan F tabel 5%. Uji lanjut menggunakan Beda Nyata Terkecil (BNT) pada taraf 5%. Hasil penelitian menunjukkan bahwa Peningkatan taraf naungan meningkatkan nilai rerata tinggi tanaman, luas daun, luas daun spesifik, dan nisbah luas daun. Disisi lain, menurunkan nilai rerata jumlah daun, bobot kering daun, bobot kering akar, bobot kering tanaman, bobot kering tajuk, laju asimilasi bersih dan laju pertumbuhan relatif Kirinyuh (Chromolaena odorata)
Pengaruh Frekuensi Penyiangan Gulma dan Jenis Pupuk Terhadap Hasil Tanaman Buncis Tegak (Phaseolus vulgaris L)
Authors: Praseptyo Ricky , Sebayang Husni Thamrin
Published: October 2022

Tanaman buncis berdasarkan data produksi tahun 2018-2020 diketahui mengalami kenaikan dan penurunan. Faktor eksternal yang mempengaruhi produksi berasal lingkungan seperti kesuburan tanah yang menurun sehingga kebutuhan tanaman tidak terpenuhi dan tumbuhnya gulma disekitar tanaman budidaya yang mengakibatkan penurunan produksi dikarenakan adanya persaingan unsur hara, air, dan penerimaan cahaya matahari serta ruang lingkup untuk tumbuh. Penelitian dilakukan dengan tujuan mempelajari jenis pupuk dan frekuensi penyiangan gulma yang baik untuk menghasilkan bobot kacang buncis paling optimal dan mempejalari jenis gulma yang mendominansi tanaman buncis tegak. Penelitian dilaksanakan pada bulan Maret-Juni 2021 berlokasi lahan penelitian Jatimulyo, Kecamatan Lowakwaru, Kabupaten Malang menggunakan Rancangan Acak Kelompok Faktorial (RAKF) yang terdiri dari 2 faktor yaitu jenis pupuk ( P1 = Pupuk Anorganik, P2 = Pupuk Organik, P3 = Pupuk Organik + Anorganik) dan frekuensi penyiangan gulma ( G0 = Tanpa Penyiangan, G1 = Penyiangan 14, 28 HST, G2 = Penyiangan 14, 21, 28 HST) Berdasarkan kedua faktor yaitu jenis pupuk dan frekuensi penyiangan gulma maka diperoleh kombinasi perlakuan sebanyak 9 dengan 3 pengulangan maka hasil keseluruhan diperoleh 27 petak percobaan. Hasil penelitian menunjukkan perlakuan pupuk organik dan anorganik dengan frekuensi penyiangan sebanyak 3x pada umur 14, 21 dan 28 HST memiliki berat kering tanaman dan bobot panen lebih tinggi dibandingkan dengan perlakuan penggunaan pupuk organik dengan tanpa penyiangan. Pada pengamatan SDR sebelum tanam didominansi oleh jenis gulma yaitu Ageratum conyzoides (35,67%) dan Ludwigia octovalvis (23,63%) sedangkan setelah dilakukan penanaman dominansi digantikan oleh Eleusine indica dengan rata-rata SDR keseluruhan perlakuan menjadi 24,13%.
Uji Daya Hasil Pendahuluan Pada 16 Galur Jagung Ungu (Zea mays L. var ceratina Kulesh)
Authors: Wahyuli Khairum Tri , Sugiharto Arifin Noor
Published: October 2022

Jagung ungu merupakan salah satu jenis jagung yang berpotensi untuk dikembangkan karena memiliki sifat ungul berupa kandungan antosianin yang bermanfaat bagi kesehatan manusia. Pada proses pengembangan jagung ungu, uji daya hasil perlu dilakukan untuk mengetahui potensi hasil dari suatu galur. Tujuan dari penelitian uji daya hasil pendahuluan pada 16 galur jagung ungu ini yaitu untuk mengetahui potensi hasil dari masing-masing galur yang diujikan sehingga didapatkan galur potensial untuk diseleksi. Penelitian ini dilaksanakan pada bulan Januari – April 2022 bertempat di Desa Jati Baru, Kecamatan Tanjung Bintang, Kabupaten Lampung Selatan. Percobaan ini menggunakan rancangan acak kelompok (RAK) dengan 17 Perlakuan dan 3 ulangan. Pengamatan dilakukan pada karakter kualitatif dan kualitatif tanaman. Analisis data kualitatif dilakukan menggunakan skoring dominan data. Sedangkan analisis data kuantitatif dilakukan menggunakan analisis ragam anova dan dilanjutkan dengan uji lanjut Beda Nyata Jujur (BNJ) dengan taraf 5%, serta perhitungan nilai KKG, KKF dan nilai heritabilitas. Hasil dari penelitian yang didapatkan bahwa setiap galur yang diuji memiliki tingkat skor keseragaman karakter kualitatif yang berbeda-beda. Sedangkan pada karakter kuantitatif, setiap karakter tanaman yang diuji menunjukan perbedaan yang nyata. Secara keseluruhan nilai penampilan karakter kuantitatif, didapatkan bahwa galur UB-UL 2, UB-UL 5, UB-UL 6, UB-UL 9, UB-UL 12, UB-UL 13, UB-UL 14 dan UB-UL 17 memiliki potensi tinggi untuk dikembangkan. Selain itu didapatkan bahwa nilai heritabilitas termasuk dalam kategori sedang – tinggi.
Ik zie, ik zie wat jij niet ziet... : Werken op het snijvlak van de biomedische en sociale wetenschappen in onderzoek naar groei van kinderen
Authors: Haisma Hinke
Published: October 2022

Ondervoeding, overgewicht en kindersterfte zijn belangrijke gezondheidsproblemen en veel onderzoek is gericht op het voorkomen ervan. Hoewel we er in slagen deze problemen gedeeltelijk aan te pakken, blijft kindersterfte, ondervoeding en overgewicht een hardnekkig probleem. En met name de ongelijkheid hierin is schrijnend. Capability model Modellen worden gebruikt om de werkelijkheid schematisch weer te geven. Elke discipline kijkt op zijn eigen manier naar deze werkelijkheid en de modellen verschillen dus ook per discipline. Voor onderzoek naar ondervoeding, overgewicht en sterfte zijn er modellen vanuit de demografie, de voedingswetenschappen, en vanuit de antropologie. Vanuit mijn onderzoeksteam voegen wij daar een model aan toe: het Capability-model voor groei van kinderen. Dit model is gebaseerd op de capability approach van Amartya Sen en Martha Nussbaum, waarbij niet uitkomsten (zoals voedingsstatus of sterfte) centraal staan, maar kansen en mogelijkheden van ouders en kinderen om te zorgen voor een goede groei. Die kansen en mogelijkheden liggen op andere terreinen dan alleen voeding en voedsel en kunnen ook gaan over vragen zoals: is er een dak boven het hoofd, hebben de ouders voldoende tijd om voor hun kind te zorgen? Een dergelijk model kan als basis dienen om niet alleen op individueel niveau, maar ook op programma- en populatieniveau op een andere manier naar groei van kinderen te kijken en dat te monitoren. Dit is relevant voor ouders die met hun kinderen naar het consultatiebureau gaan, maar ook voor het monitoren van voortgang betreffende de Sustainable Development Goals. Elkaars perspectief leren begrijpen In mijn onderzoek komen een aantal disciplines samen: demografie, voedingswetenschappen, sociologie, antropologie, ontwikkelingsstudies, economie en filosofie. Omdat deze disciplines de realiteit elk op hun eigen manier en met hun eigen modellen bekijken is het belangrijk voldoende tijd te nemen om elkaars perspectief te leren begrijpen. Dat vraagt ruimte voor contemplatie, reflectie, overleg en debat. De huidige wetenschapscultuur met zijn focus op veel publiceren en in hoogstaande tijdschriften is daarvoor niet altijd de beste broedplaats. Om tot nieuwe inzichten te komen is het echter wel belangrijk om die tijd te nemen. In mijn onderzoek hebben we die tijd genomen en ik hoop daarmee als voorbeeld en inspiratie te kunnen dienen dat minder vaak meer is. Maar dat het een lange adem vraagt.
Hepatitis B Reactivation in HBsAg Negative Renal Transplant Patients with Evidence of Previous HBV Infection: A Not Neglectable Occurrence
Authors: Leopercio Ana Paula , Emori Christini , Neiva Elisabete Calore , Silva Souza Ana Lucia , Amaral Ana Cristina , Vieira Gustavo Almeida , Gama Raimundo Araujo , Medina-Pestana Jose Osmar , Ferraz Maria Lúcia
Published: October 2022

Hepatitis B virus (HBV) infection is frequent among patients with chronic kidney disease (CKD). HBV reactivation after kidney transplant (KT) is more common in patients with HBsAg+; however, it can also occur in previously infected individuals, particularly those with HBsAg negative and total antiHBc positive (HBsAg-/antiHBcT+). However, reactivation in this population has scarce and conflicting data. This study aimed to assess the reactivation risk in KT recipients with previous HBV infection (antiHBcT+). A retrospective cohort study was conducted, including patients with KT between January 1993 and December 2012 with HBsAg+ (G1) and with previous HBV infection (antiHBcT+) (G2). A total of 10,493 transplants were performed in this period. A total of 203 patients were included (122 HBsAg+ and 81 HBsAg-/anti-HBcT+). The reactivation of infection occurred in 24.6% (30/38) patients and 9.8% (8/30) in G1 and G2, respectively. Detectable HCV RNA, indicating HCV coinfection, was the only variable related to reactivation in patients with antiHBcT+, protecting its occurrence (p: 0.001). In conclusion, reactivation of HBV infection in KT recipients with the previous infection, occurring in approximately 10% of cases, should be considered. Complete HBV serology is recommended before KT, and patients with HBsAg-/anti-HBcT+ should be monitored after the procedure. Prophylaxis may be indicated when adequate follow-up is not feasible. HCV coinfection appears to be a protective factor for reactivation.
Quality Assessment of Hypertension Treatment–Related Information on WeChat: Cross-sectional Study
Authors: Yang Yuting , Hou Mengchi , Gong Xue , Guo Rui , Feng Xing Lin , Tian Rui
Published: October 2022

Background

The WeChat platform has become a primary source for medical information in China. However, no study has been conducted to explore the quality of information on WeChat for the treatment of hypertension, the leading chronic condition.

Objective

This study aimed to explore the quality of information in articles on WeChat that are related to hypertension treatment from the aspects of credibility, concreteness, accuracy, and completeness.

Methods

We searched for all information related to hypertension treatment on WeChat based on several inclusion and exclusion criteria. We used 2 tools to evaluate information quality, and 2 independent reviewers performed the assessment with the 2 tools separately. First, we adopted the DISCERN instrument to assess the credibility and concreteness of the treatment information, with the outcomes classified into five grades: excellent, good, fair, poor, and very poor. Second, we applied the Chinese Guidelines for Prevention and Treatment of Hypertension (2018 edition) to evaluate the accuracy and completeness of the article information with regard to specific medical content. Third, we combined the results from the 2 assessments to arrive at the overall quality of the articles and explored the differences between, and associations of, the 2 independent assessments.

Results

Of the 223 articles that were retrieved, 130 (58.3%) full texts were included. Of these 130 articles, 81 (62.3%) described therapeutic measures for hypertension. The assessment based on the DISCERN instrument reported a mean score of 31.22 (SD 8.46). There were no articles rated excellent (mean score >63); most (111/130, 85.4%) of the articles did not refer to the consequences—in particular, quality of life—of no treatment. For specific medical content, adherence to the Chinese Guidelines for Prevention and Treatment of Hypertension was generally low in terms of accuracy and completeness, and there was much erroneous information. The overall mean quality score was 10.18 (SD 2.22) for the 130 articles, and the scores differed significantly across the 3 types (P=.03) and 5 sources (P=.02). Articles with references achieved higher scores for quality than those reporting none (P<.001). The results from the DISCERN assessment and the medical content scores were highly correlated (ρ=0.58; P<.001).

Conclusions

The quality of hypertension treatment–related information on the WeChat platform is low. Future work is warranted to regulate information sources and strengthen references. For the treatment of hypertension, crucial information on the consequences of no treatment is urgently needed.
A TiO2/polyurethane Composite for Photodegradation of Formaldehyde via Covalently Incorporation of Amino-functionalized TiO2
Authors: Zhu Yifan , Tian Saiqi
Published: October 2022

In this study, a TiO2/polyurethane composite (PU-TiO2) for photodegradation of formaldehyde was prepared based on TiO2 amino-functionalized with 3-aminopropyltriethoxysilane (APTS). FTIR, XPS, TG and TEM measurements demonstrated the successful amino-functionalization of TiO2 by APTS. Then the NH2-TiO2 were incorporated into polyurethane (PU) through urea linkages, and the thermal stability, mechanical properties as well as degradation efficiency of PU-TiO2 were investigated. PU-TiO2 possessed good thermal stability both in the storage and application. Compared with PU physically blended with TiO2, PU-TiO2 showed improved compatibility between PU and NH2-TiO2, evidenced by the enhanced mechanical properties. Most importantly, PU- TiO2 presented a good photoactivity for the degradation of formaldehyde.
Non-Majority Faculty Perceptions of Diversity and Inclusion at a Predominately White and Historically Black University
Authors: Campbell-Whatley Gloria , Freeman-Green Shaqwana , O’Brien Christopher , Sun Ting
Published: October 2022

In this study, we conducted survey research to examine perceptions of diversity and inclusion among majority and non-majority faculty at a Predominately White University (PWI) and a Historically Black University (HBCU), as these public institutions have distinct historical foundations regarding orientation to cultural diversity and inclusion. The study is rooted in the current national efforts to establish Inclusive Excellence (Williams et al., 2005) on university campuses. Unique in this study was an effort to examine perceptions of inclusion and diversity based on identity relative to race, gender, and sexuality given patterns historical marginalization in the context of the majority culture. T-tests and Analysis of Variance (ANOVAs) were used to determine if there are differences in faculty experiences. Results indicated significant differences between the groups and universities in perceptions and experiences of diversity and inclusion.
Review of Spin Doctors: How Media and Politicians Misdiagnosed the COVID-19 pandemic
Authors: Ma Adrian
Published: October 2022

A review of: Spin Doctors: How Media and Politicians Misdiagnosed the COVID-19 pandemic by Nora Loreto.
Minimal change disease associated with Graves’ disease and methimazole use
Authors: Rodríguez-Gutiérrez Andrés Fernando , Cabezas Sandra Liliana
Published: October 2022

Introduction. Graves' disease causes kidney injury through multiple mechanisms, including the treatment for this condition. Nephrotic syndrome due to minimal change disease (MCD) is an unusual form of such kidney injury; the association between methimazole use and MCD is also rare.

Case presentation. 36-year-old woman with a history of Graves' disease in use of methimazole for several months, who presented with edematous syndrome due to nephrotic syndrome associated with a KDIGO stage 3 acute kidney injury. Thionamide-induced hypothyroidism and the need of thyroid hormone replacement therapy  was evidenced at the time of consultation. Based on a renal biopsy, the patient was diagnosed with MCD. Her condition worsened as she experienced oliguria and hypervolemia, and renal replacement therapy with hemodialysis was temporarily required. Methimazole administration was suspended, and treatment consisting of prednisolone administration and levothyroxine supplementation was started, achieving hemodialysis suspension, gradual improvement of proteinuria until remission and full and maintained recovery of renal clearance. Radioiodine therapy was implemented as definitive treatment for Graves' disease, obtaining a successful outcome.

Conclusions. Graves' disease and methimazole use are possible causes of minimal change disease. Systemic corticosteroid therapy is a possible management. However, further basic, clinical and epidemiological research on this subject is required.
SITUASI PERDAGANGAN INTERNASIONAL DAN ANALISIS PENGARUH FAKTOR HARGA DAN PRODUKSI TERHADAP VOLUME EKSPOR KARET ALAM INDONESIA TAHUN 2015-2020
Authors: FAUZI IIF RAHMAT
Published: October 2022

Dalam beberapa tahun terakhir, perkembangan volume ekspor karet alam Indonesia menunjukkan tren yang negatif. Kondisi tersebut sejalan dengan tren produksi dan harga karet di Indonesia. Penelitian bertujuan menganalisis perkembangan volume ekspor karet alam Indonesia, pengaruh produksi, dan harga terhadap volume ekspor karet alam Indonesia tahun 2015 - 2020. Metode yang digunakan dalam penelitian ini mencakup analisis deskriptif dan analisis regresi linier berganda. Penelitian ini merupakan studi kuantitatif dengan deret waktu bulanan, yaitu Januari 2015 s.d Juni 2020. Hasil penelitian menunjukkan bahwa produksi dan harga memiliki pengaruh positif dan signifikan terhadap perkembangan volume ekspor karet alam Indonesia. Hasil uji koefisien determinasi sebesar 0,6209. Hal tersebut menunjukkan 62,09% variasi variabel terikat yang dapat dijelaskan dengan variasi variabel bebasnya. Sebagai rekomendasi hasil penelitian, upaya penanggulangan pandemi COVID-19 dan penyakit gugur daun Pestalotiopsis mutlak harus segera dilakukan dalam jangka pendek. Sementara secara fundamental pemerintah Indonesia harus mampu mendorong tercapainya peningkatan kualitas produksi dan perluasan pasar ekspor karet alam serta peningkatan produktivitas lahan perkebunan karet alam Indonesia dalam jangka panjang.