bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospects for Wood Pellet Production in Kazakhstan: A Case Study on Business Model Adjustment
Authors: Kogabayev Timur , Põder Anne , Barth Henrik , Värnik Rando
Published: August 2023

Biomass and renewable resources are becoming substitutes for fossil-based resources, providing opportunities for more sustainable environmental management and reductions in environmental damage. This paper studies the prospects for wood pellet production in Kazakhstan through the lens of business model adjustment in a microenterprise in Kazakhstan. This study focuses on answering the following questions: (1) How do microenterprises propose, create, deliver and capture value through business models in the wood industry? (2) What are the opportunities and challenges relating to these business models in the context of wood pellet production in Kazakhstan? Kazakhstan has a high potential for biomass production, providing a particularly interesting case for analysing how microenterprises can tap into this potential to create value. This paper combines an analysis of bioenergy and forestry trends with a qualitative case study. The analysis of the business model is based on Osterwalder’s business model canvas. The value proposition of the enterprise studied herein is to provide a local biomass-based alternative to fossil fuels. The overall growth of wood-based industries in Kazakhstan and the national movement towards renewable energy create favourable prospects for microenterprises engaged in the production of wood pellets; however, these industries are also characterised by high institutional and regulatory dependencies.
A Novel Strategy for Constructing Large-Scale Forest Scene: Integrating Forest Hierarchical Models and Tree Growth Models to Improve the Efficiency and Stability of Forest Polymorphism Simulation
Authors: Lei Kexin , Zhang Huaiqing , Qiu Hanqing , Yang Tingdong , Liu Yang , Zhang Jing , Hu Xingtao , Cui Zeyu
Published: August 2023

Modeling large-scale scenarios of diversity in real forests is a hot topic in forestry research. At present, there is a common problem of simple and poor model scalability in large-scale forest scenes. Forest growth is often carried out using a holistic scaling approach, which does not reflect the diversity of trees in nature. To solve this problem, we propose a method for constructing large-scale forest scenes based on forest hierarchical models, which can improve the dynamic visual effect of large-scale forest landscape polymorphism. In this study, we constructed tree hierarchical models of corresponding sizes using the detail attribute data of 29 subplots in the Shanxia Experimental Forest Farm in Jiangxi Province. The growth values of trees of different ages were calculated according to the hierarchical growth model of trees, and the growth dynamic simulation of large-scale forest scenes constructed by the integrated model and hierarchical model was carried out using three-dimensional visualization technology. The results indicated that the runtime frame rate of the scene constructed by the hierarchical model was 30.63 fps and the frame rate after growth was 29.68 fps, which met the operational requirements. Compared with the traditional integrated model, the fluctuation value of the frame rate of the hierarchical model was 0.036 less than that of the integrated model, and the scene ran stably. The positive feedback rate of personnel evaluation reached 95%. In this study, the main conclusion is that our proposed method achieves polymorphism in large-scale forest scene construction and ensures the stability of large-scale scene operation.
Quantification of Pork, Chicken, Beef, and Sheep Contents in Meat Products Using Duplex Real-Time PCR
Authors: Wang Yanwen , Teo Emily , Lin Kung Ju , Wu Yuansheng , Chan Joanne Sheot Harn , Tan Li Kiang
Published: August 2023

Accurate methods for meat speciation and quantification are essential for ensuring the supply of safe and wholesome meat and composite products with animal origins to negate the potential associated hazards, aid classification of consignments at the import control system, and thwart food fraud committed for financial gain. To better enhance meat safety control and combat food fraud, this study developed two duplex real-time polymerase chain reaction (real-time PCR) systems specifically designed for chicken, pork, sheep, and beef, using single-copy, chromosomally encoded, species-specific gene sequences to accurately measure the content of each meat type in meat products. DNA extracted from the raw and boiled reference materials prepared in varying proportions (ranging from 1% to 75%) were used in the development of the duplex assay to derive calibration factors to determine the meat content in different meat products. The method was further validated using proficiency test samples and market monitoring samples. Our findings showed that this method exhibits high specificity and sensitivity, with a significant accuracy range of 0.14% to 24.07% in quantifying the four meat types in both raw and processed meat products. Validation results further confirmed the effectiveness of our method in accurately quantifying meat content. Thus, we have demonstrated the duplex qPCR assays as promising approaches for implementation in routine analysis to strengthen meat safety control systems and combat meat fraud, thereby safeguarding consumer health and trust in the meat industry.
Dynamics of the Three-Compartment Financial Bubble Model under the Mittag-Leffler Operator
Authors: Li Bo , Chen Kaiwen , Zhang Bo
Published: August 2023

This paper presents an investigation into the dynamics of the emerging three-compartment financial bubble problem using a new non-singular kernel Atangana–Baleanu derivative operator. The problem is tested for at least one solution, and a unique root is determined using an iterative Newton approximation method, providing a globally stable fractional analysis technique. Curve sketches of the globalized model are provided, considering integers and other conformable orders. Sensitivities of the fractional order and other model parameters are examined, offering insights into their impact on the system dynamics. This research contributes to understanding financial bubbles and lays the groundwork for future studies in this field.
A Multibreed Genome-Wide Association Study for Cattle Leukocyte Telomere Length
Authors: Igoshin Alexander V. , Yudin Nikolay S. , Romashov Grigorii A. , Larkin Denis M.
Published: August 2023

Telomeres are terminal DNA regions of chromosomes that prevent chromosomal fusion and degradation during cell division. In cattle, leukocyte telomere length (LTL) is associated with longevity, productive lifespan, and disease susceptibility. However, the genetic basis of LTL in this species is less studied than in humans. In this study, we utilized the whole-genome resequencing data of 239 animals from 17 cattle breeds for computational leukocyte telomere length estimation and subsequent genome-wide association study of LTL. As a result, we identified 42 significant SNPs, of which eight were found in seven genes (EXOC6B, PTPRD, RPS6KC1, NSL1, AGBL1, ENSBTAG00000052188, and GPC1) when using covariates for two major breed groups (Turano–Mongolian and European). Association analysis with covariates for breed effect detected 63 SNPs, including 13 in five genes (EXOC6B, PTPRD, RPS6KC1, ENSBTAG00000040318, and NELL1). The PTPRD gene, demonstrating the top signal in analysis with breed effect, was previously associated with leukocyte telomere length in cattle and likely is involved in the mechanism of alternative lengthening of telomeres. The single nucleotide variants found could be tested for marker-assisted selection to improve telomere-length-associated traits.
Can High-Fidelity Patient Simulation Be Used for Skill Development in Junior Undergraduate Students: A Quasi-Experimental Study
Authors: Wong Florence M. F. , Chan Alice M. L. , Lee Natalie P. M. , Luk Kevin K. H.
Published: August 2023

High-fidelity patient simulation (HFPS) is widely used in professional training to enhance students’ competence in clinical management. A guideline for HFPS provides a systematic approach to direct students to learning during the simulation process. Problem-solving (PS) and clinical reasoning (CR) skills are essential to developing students’ professional competence in safe and effective care. These two skills should be initiated in the early training. A structured guideline was developed for HFPS. This study aimed to investigate the effects of the structured HFPS guideline on the development of PS and CR skills in junior nursing students. The students were required to go through four sessions, pre-briefing, simulation design, facilitation, and debriefing, for the HFPS; the study utilized the Problem-Solving Inventory (PSI) and the Nurses’ Clinical Reasoning Scale (NCRS) to measure PS and CR abilities before and after HFPS. Bivariate analysis, a one-sample t-test, and an independent t-test were performed to evaluate the performance of the PS and CR skills during the two study periods. A total of 189 students were recruited, with 92 in the intervention group and 97 in the control group. The research assistant was responsible for student recruitment through email invitations and allocating the students into the control group or the intervention group. A Wilcoxon analysis was performed and revealed significant differences in PS and CR between the two groups (p < 0.001). The analytic results showed that the PSI, particularly in domains of Problem-Solving Confidence (PSC) (p < 0.001) and overall PS (p < 0.001), and the CR (p < 0.001) had significant improvement after HFPS, particularly in the intervention group. The study concluded that the structured HFPS guideline significantly improved the students’ problem-solving and clinical reasoning abilities. Nurse educators play an important role in providing explicit learning instructions in a simulation guideline that directs and guides students to learn at each stage of HFPS. The students can be directed to be engaged in their learning through HFPS to enhance their competence in knowledge and skill development (PS and CR) for their personal and professional development.
Clinicians’ and Advanced Cancer Patients’ Estimates of Treatment Efficacy and Toxicity in Oncologic Treatment
Authors: Lee Eun Mi , Jiménez-Fonseca Paula , Carmona-Bayonas Alberto , Hernández Raquel , Cruz-Castellanos Patricia , Obispo Berta , Antoñanzas-Basa Mónica , Palacín-Lois María , Castillo-Trujillo Oscar A. , Calderon Caterina
Published: August 2023

The purpose of the study was to compare curability expectations between clinicians and patients and examine the influence of sociodemographic and clinical variables on these expectations and satisfaction within the clinician-patient relationship. This prospective study, conducted from February 2020 to May 2023, involved 986 advanced cancer patients. The patients completed questionnaires assessing treatment efficacy and toxicity predictions and the Scale to Assess the Therapeutic Relationship (STAR). Seventy-four percent of advanced cancer patients had an inaccurate perception of treatment curability. Clinicians perceived male patients with lung or digestive cancer without adenocarcinoma at locally advanced stages, with fewer comorbidities and better functional status (ECOG), as having higher curability expectations. Clinicians tended to have more realistic expectations than patients, since they had to consider the presence of treatment’s side effects, while patients underestimated the possibility of experiencing these adverse effects. Patients who had more favorable expectations regarding survival and quality of life were found to be more satisfied with the care provided by their oncologists. It is crucial for patients to understand the treatment goals and establish realistic expectations in order to actively participate in decision-making and achieve a better quality of life at the end of life.
Clinical Efficiency and Acceptability of EMDR and MOSAIC Therapy for PTSD
Authors: Flatot-Blin Deborah , Rey Arnaud , Derynck Flavie , Fossard Olivier , Khalfa Stephanie
Published: August 2023

Eye movement desensitization and reprocessing (EMDR) therapy is one of the therapies recommended by the World Health Organization (2013) to treat posttraumatic stress disorder (PTSD). Although efficient, repeated exposure to the traumatic memory may reduce its acceptability to patients. The therapy “eye movement and alternate stimulation for brain integration” (MOSAIC in French) was developed to improve acceptability and reduce pain by drawing on the patient’s internal resources. MOSAIC therapy focuses on the body sensations that the patient wants to experience and avoids having to relive the traumatic memories. This observational study aimed to compare the clinical efficiency of EMDR and MOSAIC therapy for PTSD and to measure the well-being generated by both therapies. Twenty-six PTSD patients (17 females and 9 males, mean age 37.01 years, SD = 13.06) received treatment by psychiatrists and/or psychologists trained with EMDR or MOSAIC therapy. Both patient groups achieved a significant decrease in PTSD symptoms as measured with the PCL-5. However, fewer sessions were required with the MOSAIC therapy than with EMDR therapy. As expected, the level of well-being experienced by the patient during the therapy, assessed using the Lickert scale, was higher with MOSAIC than with EMDR therapy from the first session. These findings provide the first evidence of the efficacy of MOSAIC therapy treatment, which now needs to be corroborated in a larger randomized clinical trial.
HMM-Based Map Matching and Spatiotemporal Analysis for Matching Errors with Taxi Trajectories
Authors: Qu Lin , Zhou Yue , Li Jiangxin , Yu Qiong , Jiang Xinguo
Published: August 2023

Map matching of trajectory data has wide applications in path planning, traffic flow analysis, and intelligent driving. The process of map matching involves matching GPS trajectory points to roads in a roadway network, thereby converting a trajectory sequence into a segment sequence. However, GPS trajectories are frequently incorrectly matched during the map-matching process, leading to matching errors. Considering that few studies have focused on the causes of map-matching errors, as well as the distribution of these errors, the study aims to investigate the spatiotemporal characteristics and the contributing factors that cause map-matching errors. The study employs the Hidden Markov Model (HMM) algorithm to match the trajectories and identifies the four types of map-matching errors by examining the relationship between the matched trajectories and the driving routes. The map-matching errors consist of Off-Road Error (ORE), Wrong-match on Road Error (WRE), Off-Junction Error (OJE), and Wrong-match in Junction Error (WJE). The kernel density method and multinomial logistic model are further exploited to analyze the spatiotemporal patterns of the map-matching errors. The results indicate that the occurrence of map-matching errors substantially varies in time and space, with variation significantly influenced by intersection features and road characteristics. The findings provide a better understanding of the contributing factors associated with map-matching errors and serve to improve the accuracy of map matching for commercial vehicles.
Fluid Biomarkers of Neuro-Glial Injury in Human Status Epilepticus: A Systematic Review
Authors: Giovannini Giada , Meletti Stefano
Published: August 2023

As per the latest ILAE definition, status epilepticus (SE) may lead to long-term irreversible consequences, such as neuronal death, neuronal injury, and alterations in neuronal networks. Consequently, there is growing interest in identifying biomarkers that can demonstrate and quantify the extent of neuronal and glial injury. Despite numerous studies conducted on animal models of status epilepticus, which clearly indicate seizure-induced neuronal and glial injury, as well as signs of atrophy and gliosis, evidence in humans remains limited to case reports and small case series. The implications of identifying such biomarkers in clinical practice are significant, including improved prognostic stratification of patients and the early identification of those at high risk of developing irreversible complications. Moreover, the clinical validation of these biomarkers could be crucial in promoting neuroprotective strategies in addition to antiseizure medications. In this study, we present a systematic review of research on biomarkers of neuro-glial injury in patients with status epilepticus.
A Probabilistic Approach to Modeling Students’ Interactions in a Learning Management System for Facilitating Distance Learning
Authors: Karapiperis Dimitrios , Tzafilkou Katerina , Tsoni Rozita , Feretzakis Georgios , Verykios Vassilios S.
Published: August 2023

Learning mostly involves communication and interaction that leads to new information being processed, which eventually turns into knowledge. In the digital era, these actions pass through online technologies. Formal education uses LMSs that support these actions and, at the same time, produce massive amounts of data. In a distance learning model, the assignments have an important role besides assessing the learning outcome; they also help students become actively engaged with the course and regulate their learning behavior. In this work, we leverage data retrieved from students’ online interactions to improve our understanding of the learning process. Focusing on log data, we investigate the students’ activity that occur close to and during assignment submission due dates. Additionally, their activity in relation to their academic achievements is examined and the response time in the forum communication is computed both for students and their tutors. The main findings include that students tend to procrastinate in the submission of their assignments mostly at the beginning of the course. Furthermore, the last-minute submissions are usually made late at night, which probably indicates poor management or lack of available time. Regarding forum interactions, our findings highlight that tutors tend to respond faster than students in the corresponding posts.
Hydrogen Incorporation in RuxTi1−xO2 Mixed Oxides Promotes Total Oxidation of Propane
Authors: Wang Wei , Wang Yu , Timmer Phillip , Spriewald-Luciano Alexander , Weber Tim , Glatthaar Lorena , Guo Yun , Smarsly Bernd M. , Over Herbert
Published: August 2023

A rational synthetic approach is introduced to enable hydrogen insertion into oxides by forming a solid solution of a reducible oxide with a less reducible oxide as exemplified with RuO2 and TiO2 (Ru_x, a mixture of x% RuO2 with (100−x)% TiO2). Hydrogen exposure at 250 °C to Ru_x (Ru_x_250R) results in substantial hydrogen incorporation accompanied by lattice strain that in turn induces pronounced activity variations. Here, we demonstrate that hydrogen incorporation in mixed oxides promotes the oxidation catalysis of propane combustion with Ru_60_250R being the catalytically most active catalyst.
Cyanoacrylate in Colorectal Surgery: Is It Safe?
Authors: D’Amore Anna , Anoldo Pietro , Manigrasso Michele , Aprea Giovanni , De Palma Giovanni Domenico , Milone Marco
Published: August 2023

Anastomotic leakage (AL) of a gastrointestinal (GI) anastomosis continues to be an important complication in GI surgery. Since its introduction more than 60 years ago, Cyanoacrylate (CA) has gained popularity in colorectal surgery to provide “prophylaxis” against AL. However, although in surgical practice it is increasingly used, evidence on humans is still lacking. The aim of this study is to analyze in humans the safety of CA to seal colorectal anastomosis. All consecutive patients from Jannuary 2022 through December 2022 who underwent minimally invasive colorectal surgery were retrospectively analyzed from a prospectively maintained database. Inclusion criteria were a histological diagnosis of cancer, a totally minimally invasive procedure, and the absence of intraoperative complications. 103 patients were included in the study; N-butyl cyanoacrylate with metacryloxisulfolane (Glubran 2®) was used to seal colorectal anastomosis, no adverse reactions to CA or postoperative complications related to inflammation and adhesions occurred; and only one case of AL (0.9%) was recorded. We can consider this study an important proof of concept on the safety of CA to seal colorectal anastomosis. It opens the possibility of starting prospective and comparative studies in humans to evaluate the effectiveness of CA in preventing colorectal AL.
Patient-Reported Outcome Measures in Patients with Thrombotic Thrombocytopenic Purpura: A Systematic Review of the Literature
Authors: Soares Ferreira Junior Alexandre , Pinheiro Maux Lessa Morgana , Kaplan Samantha , Coles Theresa M. , Terrell Deirdra R. , Onwuemene Oluwatoyosi A.
Published: August 2023

Health-related quality of life (HRQoL) impacts of thrombotic thrombocytopenic purpura (TTP) have been captured in clinical studies using patient-reported outcome (PRO) measures (PROMs) that are validated for other diseases. However, the validity evidence to support the use of existing PROMs in patients with TTP is unknown. In a systematic review of the literature, including studies of adults and children with TTP, we assessed the validity evidence for use of PROMs in clinical research and clinical practice, characterized HRQoL, described the integration of PROMs in clinical practice and evaluated PRO scores for patients with TTP compared with reference populations. From an initial 4518 studies, we identified 14 studies using 16 PROMs to assess general HRQoL domains in patients in remission. No identified studies assessed the validity of PROMs for the context of use of TTP and no studies described PROM integration into TTP clinical practice or evaluated PROMs that were specific for patients with TTP. Moreover, PRO scores were worse in patients with TTP compared with reference populations and other chronic conditions. We conclude that, in patients with TTP, PROMs pick up on important patient experiences not captured by clinical outcomes at present. There is, therefore, a need for studies that assess the validity of existing PROMs in patients with TTP to determine if TTP-specific PROMs specific to patients with TTP should be developed.
Massive Transfusion Increases Serum Magnesium Concentration
Authors: Malinowska Justyna , Małecka-Giełdowska Milena , Pietrucha Katarzyna , Górska Gabriela , Kogut Dagmara , Ciepiela Olga
Published: August 2023

(1) Background: The massive transfusion of packed red blood cells (RBCs) is a lifesaving procedure, but it is associated with complications, e.g., dysmagnesemia. Since magnesium is an intracellular ion, the transfused RBCs can significantly influence the magnesium concentration in the recipient’s blood. (2) Methods: A retrospective study was performed among 49 patients hospitalized in the Central Clinical Hospital of the Medical University of Warsaw who received a massive blood transfusion (≥4 units/h). Data on laboratory results and patient history were collected from the hospital database. The intracellular RBCs magnesium concentration was measured in 231 samples using the colorimetric method. (3) Results: There were statistically significant changes in the mean serum magnesium concentration preoperatively and 24 h postoperatively (0.87 ± 0.13 vs. 1.03 ± 0.14, p < 0.00001) and 48 h postoperatively (0.87 ± 0.13 vs. 1.06 ± 0.15, p < 0.00001). Patients who died had significantly higher serum magnesium concentrations (p < 0.05). The median intracellular magnesium concentration in RBCs was 0.91 (0.55–1.8) mmol/L, which is below the reference values of 1.65–2.65 mmol/L. (4) Conclusions: Transfused RBCs significantly increased the serum magnesium concentration 24 h and 48 h postoperatively. It could be a result of mild hemolysis, as the median intracellular magnesium concentration in RBCs was below the reference values.
Kenaf Fiber and Hemp Fiber Multi-Walled Carbon Nanotube Filler-Reinforced Epoxy-Based Hybrid Composites for Biomedical Applications: Morphological and Mechanical Characterization
Authors: Anand Praveena Bindiganavile , Nagaraja Santhosh , Jayaram Nagendra , Sreenivasa Shashank Paidi , Almakayeel Naif , Khan T. M. Yunus , Kumar Raman , Kumar Raman , Ammarullah Muhammad Imam
Published: August 2023

This study used a hybrid combination of kenaf and hemp fibers and the multi-walled carbon nanotube (MWCNT) reinforcements in the matrix phase to synthesize the composites. A kenaf/hemp fiber blend with MWCNTs in epoxy was used for the specific concentration. The procedure used three composite materials chosen from pilot trials. The ratio of MWCNT filler particles was altered up to the agglomeration limit based on initial trials. Two specimens (2 and 3) were supplemented with MWCNTs in a concentration range of 0.5 wt. % to 1 wt. %, with the fiber concentration being maintained in equilibrium with the epoxy resin, all of the materials were tested under the same conditions. The hybrid nanocomposite was characterized for its morphological and mechanical properties; the tensile properties were higher for 1% MWCNTs concentration (specimen 2), while the flexural properties were higher for 0.5% MWCNTs, with values of 43.24 MPa and 55.63 MPa, correspondingly. Once the MWCNT concentration was increased to 1 wt. %, the maximum impact strength was achieved (specimen 3). In the limits of the Shore-D scale, the kenaf fiber and hemp fiber matrix composite (specimen 1) gained a hardness index of 84. Scanning electron microscopy was carried out to analyze the morphological features of the fractured samples and to assess the adhesion between the fiber, matrix, and surface. Among the various fillers tested, the kenaf fiber/hemp/MWCNT composite (specimen 3) demonstrated superior binding and reduced the incidence of fiber pull-out, breakage, and voids. In addition to the comparative analysis, the addition of 0.5 wt. % MWCNTs resulted in better mechanical properties compared to the other two combinations.
Exercise Prescription Principles among Physicians and Physical Therapists for Patients with Impaired Glucose Control: A Cross-Sectional Study
Authors: Petrie Michael A. , Johnson Kristin A. , Dubey Olga , Shields Richard K.
Published: August 2023

Exercise confers a multitude of benefits with limited adverse side effects, making it a powerful “medication” for a plethora of diseases. In people living with uncontrolled glucose levels, exercise can be an effective “medication” to assist in the management of hyperglycemia. We sought to survey healthcare providers (physicians and physical therapists) to determine the current state of exercise recommendation for people with glucose control issues. Healthcare providers were surveyed from six academic medical centers in the Midwest to determine the recommended exercise parameters (type, frequency, duration, intensity, and timing) for patients with glucose control issues. Data from 209 practitioners who completed the survey were used for analysis. Chi-square tests were used to determine differences in exercise recommendations between physical therapists (PTs) and physicians (MD/DOs). PTs and MD/DOs recommended similar exercise parameters. Of all respondents, 78.9% recommended exercise to patients with glucose control issues. Respondents who considered themselves to be active exercisers were more likely to recommend exercise than those who were not exercisers. Only 6.1% of all respondents recommended post-meal exercise. Healthcare providers overwhelmingly recommended exercise for people with glucose control issues, but the “timing” is not congruent with best practice recommendations.
Dynamic Response Analysis of Submarines Based on FEM-ALE Coupling Method in Floating Ice Conditions
Authors: Chen Zhongyu , Zhao Weidong , Chen Zhanyang , Feng Guoqing , Ren Huilong , Gui Hongbin
Published: August 2023

To address global challenges, research on the safety of polar navigation is indispensable. However, most of studies focus on traditional surface vessels, with few research studies on submarine. The dynamic response of submarine during surface navigation in floating ice channels under special conditions is studied in this work. Firstly, a model of the submarine incorporating an intact internal frame was established. Subsequently, the FEM-ALE coupled method was employed to simulate the structure-ice interaction, and the obtained results was verified by the Colbourne method. Then, the parametric study (navigation speed, ice thickness, and floating ice size) were analyzed from the perspectives of ice resistance, stress and plastic strain. Finally, an empirical equation suitable for the interaction between submarine and floating ice during surface navigation is improved based on the Colbourne method.
Runoff and Sediment Yield Processes in a Tropical Eastern Indian River Basin: A Multiple Machine Learning Approach
Authors: Moghaddam Nia Alireza , Misra Debasmita , Kashani Mahsa Hasanpour , Ghafari Mohsen , Sahoo Madhumita , Ghodsi Marzieh , Tahmoures Mohammad , Taheri Somayeh , Jaafarzadeh Maryam Sadat
Published: August 2023

Tropical Indian river basins are well-known for high and low discharges with high peaks of flood during the summer and the rest of the year, respectively. A high intensity of rainfall due to cyclonic and monsoon winds have caused the tropical Indian rivers to witness more runoff. These rivers are also known for carrying a significant amount of sediment load. The complex and non-linear nature of the sediment yield and runoff processes and the variability of these processes depend on precipitation patterns and river basin characteristics. There are a number of other elements that make it difficult to forecast with great precision. The present study attempts to model rainfall–runoff–sediment yield with the help of five machine learning (ML) algorithms—support vector regression (SVR), artificial neural network (ANN) with Elman network, artificial neural network with multilayer perceptron network, adaptive neuro-fuzzy inference system (ANFIS), and local linear regression, which are useful in river basins with scarce hydrological data. Daily, weekly, and monthly runoff and sediment yield (SY) time series of Vamsadhara river basin, India for a period from 1 June to 31 October for the years 1984 to 1995 were simulated using models based on these multiple machine learning algorithms. Simulated results were tested and compared by means of three evaluation criteria, namely Pearson correlation coefficient, Nash–Sutcliffe efficiency, and the difference of slope. The results suggested that daily and weekly predictions of runoff based on all the models can be successfully employed together with precipitation observations to predict future sediment yield in the study basin. The models prepared in the present study can be helpful in providing essential insight to the erosion–deposition dynamics of the river basin.
Caradiophyodidae, a New Family of Micro-Wasps (Hymenoptera: Platygastroidea) Based on the Description of Caradiophyodus saradae gen. et sp. nov. in Mid-Cretaceous Burmese Amber
Authors: Poinar George , Vega Fernando E.
Published: August 2023

The female micro-wasp in mid-Cretaceous Burmese amber is described as a new genus and species in the extinct family Caradiophyodidae fam. nov. (Hymenoptera: Platygastroidea). Features of the specimen are its small body size (1.3 mm), no elbows, elongated, 15-segmented antennae, a deep cleft in the top of its head, a tarsal formula of 5-5-5, a reduced venation with a small pterostigma but no uncus in the forewing, no anal lobe in the hind wing, and a possible coiled ovipositor in the metasoma. Large unidentified expanded structures, considered to be possible seeds, plant secretions, or host eggs, are attached to each antenna.
Chronic Prostatitis/Chronic Pain Pelvic Syndrome and Male Infertility
Authors: Graziani Andrea , Grande Giuseppe , Martin Michel , Ferraioli Giordana , Colonnello Elena , Iafrate Massimo , Dal Moro Fabrizio , Ferlin Alberto
Published: August 2023

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is defined as urologic pain or discomfort in the pelvic region, associated with urinary symptoms and/or sexual dysfunction, lasting for at least 3 of the previous 6 months. The rate of symptoms related to prostatitis has a mean prevalence of 8–8.2%. CP/CPPS is most frequent in men younger than 50 years, among whom it is the most common urologic diagnosis. In the last decades, many studies have been published on CP/CPPS and its association with male infertility. The pathophysiologic relation between CP/CPPS and male infertility involves several aspects, which are not well studied yet. A reduction in semen parameters has been demonstrated in patients with CP/CPPS, and several mechanisms have been proposed to represent putative pathophysiological links between CP/CPPS and infertility, including male accessory gland inflammation, metabolic syndrome, inflammatory bowel disease, HPV co-infection and autoimmunity. In light of this evidence, a multidisciplinary approach is advocated for patients with known CP/CPPS, and particular attention is needed for male patients of infertile couples in order to evaluate male accessory glands correctly. In addition, it is advisable that future studies dealing with the treatment of CP/CPPS take into consideration all the different pathophysiological aspects implicated.
The Effect of the Cu Interlayer on the Interfacial Microstructure and Mechanical Properties of Al/Fe Bimetal by Compound Casting
Authors: Liu Shiyuan , Xu Hong , Zhang Baohong , Zhang Guowei , Bai Long , Song Heqian , Zhang Dan , Chang Chao , Yu Huan , Yang Chenglong
Published: August 2023

Al/Fe bimetals prepared by a compound casting method, combining the excellent properties of both the Al alloy and the ductile cast iron, exhibit great potential for application in achieving engine weight reduction. However, the problem of insufficient interfacial bonding ability because of the difference in thermophysical properties of Al and Fe is particularly prominent. Therefore, in this work, the electrodeposited Cu coating on the surface of the Fe matrix was used as the interlayer of Al/Fe bimetal fabricated by coupling hot-dipping with compound casting to solve the above problem. The effect of Cu interlayer thickness on the interfacial microstructure and shear strength of bimetal was investigated. The experimental results showed that the shear strength up to 77.65 MPa in regard to Al/Fe bimetal with a 5 μm Cu interlayer was obtained. No Cu element was detected at the interface of bimetal regardless of the thickness of the Cu interlayer. The diffusion behavior of the Cu atom at the interface and the influence of the Cu layer at the atomic scale on diffusion reaction and the Al/Fe interface were further revealed by combining first-principle and molecular dynamics calculations. The simulation results revealed that the Cu layer gradually dissolved into an Al alloy at 750 °C, thereby promoting the diffusion reaction of the Al/Fe interface. Meanwhile, the protective role of the Cu layer against oxidation on the surface of the Fe matrix was confirmed. As a result, the interfacial bonding performance was enhanced when the Cu interlayer was introduced.
A Discrete-Finite Element Analysis Model Based on Almen Intensity Test for Evaluation of Real Shot Peening Residual Stress
Authors: Wang Chengan , Park Yujin , Kim Taehyung
Published: August 2023

In this study, a combined discrete-finite element model based on the Almen intensity measurement test was proposed to evaluate the real shot peening residual stress. The discrete element analysis was utilized to simulate the random behavior of numerous shot balls, while the finite element analysis was employed to quantitatively predict the residual stress induced by shot peening. Moreover, the Almen intensity, an essential factor in the actual shot peening process, was taken into account. Initially, an Almen strip analysis model was established, and the multi-random impact analysis was performed to validate the good agreement between the analytical Almen curve and experimental Almen curve. Subsequently, the unit cell discrete-finite element analysis model was expanded for predicting the peening residual stress, incorporating the Almen intensity. The analysis results showed a significant correlation between the predicted peening residual stress and the XRD (X-ray diffraction) experimental residual stress. Therefore, it was confirmed that the proposed discrete-finite element random impact analysis model in this study could serve as an effective analytical technique capable of substituting for the actual shot peening process.
Effects of Wire Electrical Discharge Finishing Cuts on the Surface Integrity of Additively Manufactured Ti6Al4V Alloy
Authors: Oniszczuk-Świercz Dorota , Świercz Rafał
Published: August 2023

The Selective laser melting (SLM) technology of recent years allows for building complex-shaped parts with difficult-to-cut materials such as Ti6Al4V alloy. Nevertheless, the surface integrity after SLM is characterized by surface roughness and defects in the microstructure. The use of additional finishing technology, such as machining, laser polishing, or mechanical polishing, is used to achieve desired surface properties. In this study, improving SLM Ti6Al4V alloy surface integrity using wire electrical discharge machining (WEDM) is proposed. The influence of finishing WEDM cuts and the discharge energy on the surface roughness parameters Sa, Svk, Spk, and Sk and the composition of the recast layer were investigated. The proposed finishing technology allows for significant improvement of the surface roughness by up to 88% (from Sa = 6.74 µm to Sa = 0.8 µm). Furthermore, the SEM analyses of surface morphology indicate improving surface integrity properties by removing the balling effect, unmelted particles, and the presence of microcracks. EDS analysis of the recast layer indicated a significant influence of discharge energy and the polarization of the electrode on its composition and thickness. Depending on the used discharge energy and the number of finishing cuts, changes in the composition of the material in the range of 2 to 10 µm were observed.
A Hypersurfaces of Revolution Family in the Five-Dimensional Pseudo-Euclidean Space E25
Authors: Li Yanlin , Güler Erhan
Published: August 2023

We present a family of hypersurfaces of revolution distinguished by four parameters in the five-dimensional pseudo-Euclidean space E25. The matrices corresponding to the fundamental form, Gauss map, and shape operator of this family are computed. By utilizing the Cayley–Hamilton theorem, we determine the curvatures of the specific family. Furthermore, we establish the criteria for maximality within this framework. Additionally, we reveal the relationship between the Laplace–Beltrami operator of the family and a 5×5 matrix.
Inverse Problem for a Fourth-Order Hyperbolic Equation with a Complex-Valued Coefficient
Authors: Imanbetova Asselkhan , Sarsenbi Abdissalam , Seilbekov Bolat
Published: August 2023

This paper studies the existence and uniqueness of the classical solution of inverse problems for a fourth-order hyperbolic equation with a complex-valued coefficient with Dirichlet and Neumann boundary conditions. Using the method of separation of variables, formal solutions are obtained in the form of a Fourier series in terms of the eigenfunctions of a non-self-adjoint fourth-order ordinary differential operator. The proofs of the uniform convergence of the Fourier series are based on estimates of the norms of the derivatives of the eigenfunctions of a fourth-order ordinary differential operator and the uniform boundedness of the Riesz bases of the eigenfunctions.
Polymicrobial Bacterial Meningitis in a Patient with Chronic Suppurative Otitis Media: Case Report and Literature Review
Authors: Vâţă Andrei , Irimie-Băluţă Erika , Roşu Florin Manuel , Onofrei Ioana Maria , Loghin Isabela Ioana , Perţea Mihaela , Avădanei Andrei Nicolae , Miron Mihnea , Rădulescu Luminiţa , Eşanu Irina , Luca Cătălina Mihaela
Published: August 2023

Polymicrobial meningitis is a rare entity in the adult population, especially in the antibiotic era. However, disorders such as chronic suppurative otitis media (CSOM) or even poor oral hygiene are considered risk factors for the development of such cerebral infection. We report a case of polymicrobial meningitis associated with oto-mastoiditis in a 64-year-old female patient known to have CSOM. The patient presented atypical symptoms for community-acquired meningitis, showing subacute evolution of headache, without fever or neck stiffness. The aerobe microorganisms Streptococcus anginosus and Corynebacterium spp., sensitive to beta-lactamines, and the anaerobe Prevotella spp., resistant to penicillin and metronidazole, were isolated from CSF specimens, while Proteus mirabilis and Enterococcus faecalis were identified from the ear drainage. The diversity of pathogens identified in our case led us to the hypothesis of two different sources of meningitis: otogenic and/or odontogenic. Favorable evolution was obtained after a multi-disciplinary approach, combining surgery and broad-spectrum antibiotics. In addition, we performed a literature review that highlights the low incidence of polymicrobial mixed aerobe–anaerobe meningitis.
Bilateral Bi-Level Erector Spinae Plane Blocks as a Part of Opioid-Sparing Multimodal Analgesia in Scoliosis Surgery: A Case Series of Six Pediatric Patients
Authors: Domagalska Malgorzata , Ciftci Bahadir , Kolasinski Jerzy , Kowalski Grzegorz , Wieczorowska-Tobis Katarzyna
Published: August 2023

Background and Aim: Postoperative pain after scoliosis surgery is severe and usually requires long-term intravenous opioid therapy. Local anesthetic options, such as wound infiltration, are limited and include neuraxial analgesia. However, they are rarely used due to side effects and inconsistent efficacy. We report an opioid-sparing multimodal analgesia regimen with bilateral erector spinae plane blocks. This case series evaluated the analgesic effect of the bilateral bi-level erector spinae plane blocks (ESP) in congenital and neurogenic scoliosis surgery. Patients and Methods: Six pediatric patients with congenital or neurogenic scoliosis underwent posterior spinal fusion involving 5 to 12 vertebral levels. Bilateral single-injection ESPB was performed at one or two levels before incision. Preoperatively, patients received intravenous dexamethasone. General anesthesia with endotracheal intubation and volume-controlled ventilation was performed via TIVA with remifentanil and propofol. During and after the procedure, the basic hemodynamic parameters, opioid consumption, pain scores (numerical rating scale/NRS), and possible block complications were monitored. Results: All the patients experienced minimal postoperative pain levels. In addition, on the first day after surgery, they had low opioid requirements with no side effects. Conclusions: ESPB in patients undergoing congenital and neurogenic scoliosis correction surgery seems to be an essential analgesic technique that may reduce both severities of pain and opioid consumption.
Metal Recovery and Separation from Wastes
Authors: Wang Lijun , Liu Shiyuan
Published: August 2023

With the development of society, large amounts of solid waste (slag, sludge, tailing, electronic waste, etc [...]
Cr2S3-Cr2O3/Poly-2-aminobenzene-1-thiol as a Highly Photocatalytic Material for Green Hydrogen Generation from Sewage Water
Authors: Rabia Mohamed , Elsayed Asmaa M. , Abdallah Alnuwaiser Maha
Published: August 2023

This study highlights the utilization of the Cr2S3-Cr2O3/P2ABT nanocomposite photoelectrode for efficient and highly sensitive photon absorption, enabling the generation of green hydrogen through the production of hot electrons upon illumination. The nanocomposite is synthesized via a one-pot reaction using K2Cr2O7 and 2-aminobenzene-1-thiol monomer, and the presence of Cr2S3-Cr2O3 is confirmed by XRD and XPS analysis within the composite. The optical properties of the Cr2S3-Cr2O3/poly-2-aminobenzene-1-thiol composite exhibit wide spectral coverage from UV to IR, with a bandgap of 1.6 eV. The diverse morphological behavior observed in the composite correlates with its optical properties, with the cleft spherical particles of the pure polymer transforming into rod-like structures embedded within the polymer matrix. The generated hydrogen gas demonstrates an impressive efficiency of 40.5 mole/10.cm2.h through electrochemical testing. The current density (Jph) values are evaluated under different light frequencies using optical filters ranging from 730 to 340 nm, resulting in Jph values of 0.012 and 0.014 mA.cm−2, respectively. These findings present a promising avenue as green hydrogen for industrial applications, leveraging the potential of the Cr2S3-Cr2O3/P2ABT nanocomposite photoelectrode.
Aspergillus nomiae and fumigatus Ameliorating the Hypoxic Stress Induced by Waterlogging through Ethylene Metabolism in Zea mays L.
Authors: Rahman Khalil Ur , Ali Kashmala , Rauf Mamoona , Arif Muhammad
Published: August 2023

Transient and prolonged waterlogging stress (WS) stimulates ethylene (ET) generation in plants, but their reprogramming is critical in determining the plants’ fate under WS, which can be combated by the application of symbiotically associated beneficial microbes that induce resistance to WS. The present research was rationalized to explore the potential of the newly isolated 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase-producing fungal endophytic consortium of Aspergillus nomiae (MA1) and Aspergillus fumigatus (MA4) on maize growth promotion under WS. MA1 and MA4 were isolated from the seeds of Moringa oleifera L., which ably produced a sufficient amount of IAA, proline, phenols, and flavonoids. MA1 and MA4 proficiently colonized the root zone of maize (Zea mays L.). The symbiotic association of MA1 and MA4 promoted the growth response of maize compared with the non-inoculated plants under WS stress. Moreover, MA1- and MA4-inoculated maize plants enhanced the production of total soluble protein, sugar, lipids, phenolics, and flavonoids, with a reduction in proline content and H2O2 production. MA1- and MA4-inoculated maize plants showed an increase in the DPPH activity and antioxidant enzyme activities of CAT and POD, along with an increased level of hormonal content (GA3 and IAA) and decreased ABA and ACC contents. Optimal stomatal activity in leaf tissue and adventitious root formation at the root/stem junction was increased in MA1- and MA4-inoculated maize plants, with reduced lysigenous aerenchyma formation, ratio of cortex-to-stele, water-filled cells, and cell gaps within roots; increased tight and round cells; and intact cortical cells without damage. MA1 and MA4 induced a reduction in deformed mesophyll cells, and deteriorated epidermal and vascular bundle cells, as well as swollen metaxylem, phloem, pith, and cortical area, in maize plants under WS compared with control. Moreover, the transcript abundance of ethylene-responsive gene ZmEREB180, responsible for the induction of the WS tolerance in maize, showed optimally reduced expression sufficient for induction in WS tolerance, in MA1- and MA4-inoculated maize plants under WS compared with the non-inoculated control. The existing research supported the use of MA1 and MA4 isolates for establishing the bipartite mutualistic symbiosis in maize to assuage the adverse effects of WS by optimizing ethylene production.