bluuebunny/crossref_metadata_2025 huggingface dataset:
An Article Review Step by Step About Preventive Measures to Prevent Infection by Covid-19 in Dental Clinic
Authors: Ali Mohammed Hussein
Published: October 2024

A huge public health concern is the advent of the COVID-19 pandemic. As dentists, both our dental staff and our patients have significant roles in reducing their susceptibility to infection. The team is at a high risk of infectious infection and likely spread of viruses because of the existence of our job. One of the best strategies to combat this pandemic is to facilitate successful social isolation. As dental professionals, though, we are confronting the double task of shielding our staff and shielding our patients from exposure to the environment from all sides by ensuring that our patients continue to be able to receive urgency / emergency dental services. Both the dentist / dental staff and the patient are at a strong risk of cross-infection because of their existence, and this is for many reasons, the most two important reasons which are 1) the needed distancing between dental worker and the patient (which is about one to two meters) that we can’t save it during dental treatment. 2) The dental treatment is applied inside the oral cavity which is the biggest source of contamination with the virus especially when we use high speed hand piece with cooling water that lead to highly spread of aerosols, which are loaded by blood and saliva droplet containing viruses, that spread to the environment of dental room and surfaces.
 Therefor the COVID-19 pandemic, has led to the absolute requirement for strict and effective infection control protocols beyond those that already exist within the dental setting. The purpose of this position statement is to establish a standard operating protocol for dental practice
La influencia de la inteligencia artificial en la creatividad y el pensamiento crítico en estudiantes universitarios.
Authors: Loáiciga Gutiérrez Jorge Luis , Chanto Espinoza Carlos Luis , Chaves Jaén Cristhian
Published: October 2024

Este artículo tiene como objetivo de investigación las conocer consecuencia de la Inteligencia Artificial (IA) en el pensamiento crítico y la creatividad en la formación educativa por parte de la población estudiantil universitaria, tomando como referencia la Universidad Nacional de Costa Rica (UNA), Campus Liberia. Para ello, se ha recopilado información de una muestra de 160 personas estudiantes matriculados en el primer ciclo del año 2024, utilizando un enfoque mixto y una encuesta en línea por medio de Google form. Como resultados se destaca que los estudiantes participantes se muestran indecisos tras evidenciar una opción de neutralidad en cuanto a los efectos de la IA con la creatividad donde si existe sumisión en el uso de aplicaciones IA y muestran perdidas de destrezas de pensamiento crítico y el análisis exhaustivo de las situaciones se ve afectado por la inmediatez de los datos disponibles. Finalmente, se presentan siete percepciones o preocupaciones que tiene el estudiantado ante la IA: la holgazanería, la inmediates de los resultados, conformismo, perdida de razonamiento, preocupa el empleo, no hay efectos y adaptabilidad.
Effectiveness of Online Information Sources on Medication Knowledge, Health-Behavior and Health Management Practices Associated with Osteonecrosis of the Jaw among Dental Professionals
Authors: Ofluoglu Duygu
Published: October 2024

Background: Medication-related osteonecrosis of jaw (MRONJ) is referred to as a complication which impacts patients' both mental and physical health conditions and requires antiangiogenic or antiresorptive therapy, particularly when they feel traumatic toothache, neuralgia in
maxillofacial area and sleep disorders. Besides effective treatment, such patients also need a complete knowledge of medication and health behavioral management strategies associated with MRONJ. Methodology: This study focuses on evaluating the effectiveness of online information sources
on Medication Knowledge, Health behavior as well as Health Management Practices associated with MRONJ among dental professionals. For this purpose, a cross-sectional research design was used with a sample of 240 participants, comprising 160 dental professionals and 80 dental trainees, in Turkey.
The data was gathered via an electronic self-administered questionnaire. SPSS software was used for the data analysis and the level of significance was maintained at p < 0.05. At the same time, a chi-square test was performed for comparing categorical variables. Results: The results
obtained from this study showed that 160 of the participants utilized online sources in order to obtain Medication Knowledge for antiresorptive medications while 80 of the participants used these sources for obtaining information regarding antiangiogenic medications. However, insignificant
differences were obtained in this regard, emphasizing the increased utilized for different online information sources to improve the Medication Knowledge regarding antiangiogenic or antiresorptive therapy in the context of MRONJ among dental professionals.
Estrategias para fomentar la participación del modelo STEM con equitativa de género en TecNM Roque
Authors: Rodríguez Segura Erik Fabian , Cupul Moreno Laura , Mondragón Moreno Wendy , Guevara Acevedo Luis Patricio
Published: October 2024

Este articulo busca documentar una propuesta de aprendizaje mediante la investigación y la experimentación, motivando al estudiante a descubrir, llegar a conclusiones y diseñar métodos para ejecutar lo que ha sido investigado. La enseñanza en contexto, para serle fiel al concepto meta-disciplinario de la metodología STEM para los Tecnológicos. Si no se enseña en contexto, se estaría, simplemente, enseñando ciencia o matemática de forma aislada. Se pretende mejorar la retención de los conceptos aprendidos, importante su promoción en relación a la toma de decisiones para la formación de investigadores y líderes con competencias resolutivas frente a los desafíos de una sociedad cada vez más avanzada. Al plantear una estrategia de mejora y el desarrollo de habilidades para fomentar la participación equitativa de género del modelo de aprendizaje desarrollo de habilidades e identificar estrategias para fomentar la participación equitativa de género del modelo de aprendizaje STEM en el TecNM Roque se busca contrarrestar la percepción negativa de sí mismas que las mujeres pueden tener en relación con las disciplinas.
Qué piensan los tripulantes pesqueros de las transformaciones del trabajo y crisis de la pesca industrial en Iquique
Authors: Ocaranza Sepúlveda Yerko
Published: October 2024

El presente artículo recoge los resultados de una investigación sobre la experiencia de los tripulantes pesqueros de los complejos Camanchaca y Corpesca, en Iquique, relacionándola con los cambios del trabajo en el rubro (específicamente en el barco) y las crisis que han golpeado a la industria pesquera en Tarapacá. Se reconstruyen las trayectorias laborales de estos trabajadores y se describen configuraciones que establecieron en ámbitos cotidianos de la faena de pesca. También se indaga en torno a las percepciones de los periodos de crisis que atraviesan el sector, las estrategias de adaptación que los tripulantes han implementado y su posición sobre el declive de la industria.
Medicina culinária: relato de experiência de uma disciplina eletiva para alunos de medicina
Authors: Bueno Marina de Andrade Maia Galvão , Watanabe Juliana Aiko , Katekawa Adriana , Cruz Marcela Rassi da , Alvarenga Tassiane , Machado Ghina Katharine Eugenia Dourado Meira , Yarak Samira , Martinez Daniel , Nascimento Paula Pires , Szajubok Nicole Tanenbaum , Ahrens Caroline
Published: October 2024

Introdução: O aumento global da alimentação não saudável está intimamente ligado a uma tendência de redução na preparação da comida feita em casa. Já existem estudos que mostram uma associação positiva entre o aumento das habilidades culinárias e a redução de risco cardiovascular. O baixo tempo destinado à educação nutricional no currículo das faculdades de Medicina contrasta com as altas taxas de mortalidade atribuíveis à má alimentação. A medicina culinária (MC), que traz uma nova abordagem educacional, baseada em evidências científicas, cujo objetivo é ensinar o poder que a comida tem sobre a saúde e melhorar os comportamentos alimentares dos profissionais de saúde e, consequentemente, de seus pacientes. Metodologia: Trata-se de um relato da experiência em que se desenvolveu uma disciplina eletiva de MC na Escola Paulista de Medicina da Universidade Federal de São Paulo (Unifesp) que resultou em um relato de experiência, com abordagem qualitativa, realizado com 18 alunos que participaram de encontros semanais durante cinco semanas de forma 100% online, por meio da plataforma Zoom. Os dados deste estudo foram coletados por meio de portfólios, com relato da experiencia. A avaliação do material foi feita por meio de análise temática. Aplicou-se um questionário que avaliou o Índice de Habilidades Culinárias, tendo como referencial teórico o Guia Alimentar para a População Brasileira. Resultados: Existem inúmeros desafios, como a conscientização dos médicos sobre a importância desse assunto, que muitas vezes parece ser mais prático do que técnico, e a subjetividade do tema sobre mudança de comportamento de médicos e pacientes. Os resultados deste estudo evidenciam que os alunos que realizaram a eletiva acreditam que essa reformulação curricular é extremamente importante e urgente. Conclusão: Observa-se uma tendência mundial de transformação da grade curricular dos profissionais da saúde, e acredita-se que esse processo pode ser iniciado nas faculdades de Medicina por meio de disciplinas eletivas de MC como a que foi implementada na Escola Paulista de Medicina da Unifesp.
A Rare Entity of Idiopathic Clitoromegaly with HBsAg Positive Status Managed with Dorsal Nerve Sparing Clitoroplasty
Authors: Maharjan N , Pokharel PB , Lamichhane A , Dahal P
Published: October 2024

Clitoromegaly, defined as an enlarged clitoris with a clitoral index of more than 35 mm2 is a frequently seen congenital malformation but an idiopathic entity is a rare one. The most acceptable method of treatment of clitoromegaly is clitoroplasty with preservation of neurovascular pedicle to glans to achieve normal genital anatomy and to preserve tactile sensation. We present a rare case of idiopathic clitoromegaly managed by dorsal nerve sparing reduction clitoroplasty in an HBsAg-positive patient.
Revitalizing Ancestral Values through Technology: Using Wayang Kulit to Engage Gen Z in Cultural and Educational Innovation
Authors: Kasinathan Vinothini , Rubasundram Geetha A. , Fuu Wong Chai
Published: October 2024

“Wayang Kulit” is a cultural heritage that combines art, storytelling, education and creativity. Although it has many charms, the lack of awareness as well as opportunity to witness this art and the perceived indifference amongst the younger generation is slowing diminishing the impact of the Wayang Kulit especially in line with ancestral values and education. This research aimed to assess if technology and education using the Wayang Kulit could be an attractive learning tool for Gen Z to apply ancestral culture and values within a modern context. In order to make it more attractive and relevant from a technology perspective, the participants selected were undergraduates from Asia Pacific University of Technology and Innovation (APU) pursuing courses in Multimedia and Games Development. The participants were required to create a short video between 2 to 3 minutes embedding the art of “Wayang Kulit” using popular stories linking it to the Sustainable Development Goals (SDG) for a competition known as “Videre Lumina”. The participants were also interviewed to understand further their experience and whether the “Wayang Kulit” could potentially be a strong asset in educational innovation. This qualitative study used the Social Learning Theory (SLT) and analyzed the videos and interviews using Pragmatist Thinking and Interpretative Phenomenological Analysis. The results reflected positive feedback towards “Wayang Kulit” and the stories behind it. The students were also enthusiastic with the learning process and the ability to communicate their story-telling skills from a multitude of ways including expressing themselves digitally through the stories, backgrounds, music, characters and the puppets. The link to culture was especially noted when participants of different backgrounds portrayed the same characters as hero’s or villain’s depending on their culture or heritage stories. Therefore, the “Wayang Kulit” is definitely an intangible asset that should be continued and celebrated as its benefits and charm can impact education, values and be used as a social engineering tool. The use of technology also provides further opportunities to expand the opportunity to watch this art and further create awareness and appreciation for its value.
Desafíos éticos y metodológicos de la inteligencia artificial generativa en educación superior: Revisión bibliométrica
Authors: Fanning Balarezo María Margarita , Vásquez Pérez María Rosa , Noblecilla Montealegre Emma Virginia
Published: October 2024

La inteligencia artificial generativa es una tecnología con aplicaciones significativas en la educación superior, pero presenta desafíos éticos y metodológicos en su implementación en la academia. Este estudio analizó, mediante métodos bibliométricos, la producción científica sobre la inteligencia artificial generativa y su integración en la educación superior, identificando los desafíos mencionados. Se revisaron 903 documentos publicados en Scopus entre 1986 y 2024. Los resultados evidencian un notable aumento en la producción científica desde 2014. Autores como Hwang GJ y Wang Y han contribuido significativamente mediante colaboraciones internacionales e interdisciplinarias. Revistas como "Sustainability (Switzerland)" e "International Journal of Educational Technology in Higher Education" son las más influyentes en este campo. Geográficamente, Estados Unidos y China lideran la producción científica. La investigación cubre diversas áreas del conocimiento, con una concentración en ciencias de la computación y sociales, lo que resalta la naturaleza multidisciplinaria del campo. Los temas principales incluyen la alfabetización en inteligencia artificial y su conexión con la industria 4.0, mientras que la gestión de grandes datos aún requiere mayor atención. La espectroscopía muestra tres periodos clave: 1951,2020 y 2023 en la producción y aplicación de la IA. Los desafíos éticos, comprenden la privacidad y protección de datos, el sesgo algorítmico y la transparencia en el uso de la inteligencia artificial; y, en los metodológicos se destaca la necesidad de desarrollar infraestructuras tecnológicas adecuadas, proporcionar formación continua a los docentes e integrar la inteligencia artificial en el currículo educativo. Las limitaciones incluyen la resistencia al cambio, desigualdades en infraestructura y altos costos de implementación. Se subraya la importancia de políticas claras y regulaciones para el uso ético y responsable de la inteligencia artificial generativa, así como el desarrollo de más investigaciones longitudinales que consideren el contexto cultural y socioeconómico.
A Decision Theoretic Approach to Student Placement
Authors: Higgins James , Schwenke James
Published: October 2024

A decision theoretic approach is proposed for scheduling a student into a future course when there is more than one possible choice. The statistical aspects of the decision theoretic placement procedure are discussed in detail. A linear model approach is given for utilizing items in a student’s records to estimate the probabilities of attaining various levels of performance or achievement as measured by an appropriate criterion. The probabilities so obtained are combined with subjective judgements via a utility function to arrive at a placement decision. An example is included illustrating the procedure for placing junior high mathematics students into one of two possible math courses.
LA HUELLA ECOLÓGICA EN LOS DESTINOS TURÍSTICOS DE QUINTANA ROO: RAZÓN PARA FOMENTAR EL TURISMO COMUNITARIO
Authors: Ken Rodríguez Crucita Aurora , Vargas García Daniel
Published: October 2024

El turismo de sol y playa que coincide con el de masas está repercutiendo en el patrimonio natural de los destinos más concurridos. Quintana Roo, por excelencia, atrae este tipo de turismo, desde Cancún hasta Bacalar, es el tipo de turismo más recurrido por los visitantes y es apoyado por el gobierno en programas de mercadotecnia turística. Existe, iniciativas de turismo rural, sustentable en todo el territorio que no recibe mayor atención de las políticas públicas. Este estudio exploratorio presenta una revisión de la literatura sobre la huella ecológica, el turismo de masas y el comunitario, luego esboza resultados de estudios de la huella ecológica causada por el turismo de masas en Quintana Roo y finalmente señala resultados de investigaciones sobre el turismo comunitario en Quintana Roo y su relación con la sustentabilidad. El objetivo de este estudio es esbozar la huella ecológica causado por los destinos turísticos de Quintana Roo y la posibilidad de mitigación por medio del turismo comunitario. Se trabaja con datos estadísticos y documentos disponibles. Lo anterior permite definir que el rumbo sustentable del turismo en Quintana Roo es el turismo comunitario al provocar una menor huella ecológica.
ANÁLISIS Y VISUALIZACIÓN DE PERCEPCIONES DE ALUMNOS DE INGENIERÍA INFORMÁTICA SOBRE COMPETENCIAS GENÉRICAS
Authors: Lázaro Hernández Pablo , Suárez Téllez Liliana
Published: October 2024

Este estudio tiene como propósito aportar en los proyectos del eje estratégico de fortalecimiento de la calidad educativa del TecNM, en los proyectos de Actualización del modelo educativo y de Evaluación de los programas educativos. El rediseño curricular es un proceso integral y complejo orientado a garantizar la pertinencia del perfil del egresado y los medios, estrategias y recursos para lograrlo. Este artículo se concentra en la percepción de logro de las competencias genéricas de cuatro grupos de estudiantes de la carrera de Ingeniería Informática del TESCHA. Para el desarrollo de la metodología se usan técnicas de análisis y visualización de datos. Entre los principales resultados, los estudiantes perciben que desarrollan las competencias de Análisis y síntesis, Conocimientos generales básicos y Manejo de la computadora. Por el contrario, hay área de oportunidad en las competencias de Comunicación con profesionales de otras áreas, Conocimiento de culturas y costumbres de otros países y Conocimiento de una segunda lengua. Incluso una muestra no representativa es un indicador de los grandes retos que tiene el TESCHA en el ámbito curricular.
IMPACTOS DAS ALTERAÇÕES RECENTES NA LEI MARIA DA PENHA: UMA ANÁLISE CRÍTICA DAS NOVAS MEDIDAS DE PROTEÇÃO ÀS MULHERES VÍTIMAS DE VIOLÊNCIA DOMÉSTICA
Authors: Lima Paulo Rolon de
Published: October 2024

The Maria da Penha Law (Law No. 11,340/2006) is a milestone in the fight against domestic and family violence against women in Brazil, and is internationally recognized for its relevance. However, over the years, it has been necessary to adapt it to face new challenges and ensure its effectiveness. This research analyzes the changes made to the Law, seeking to identify the potentialities and limitations of these changes in strengthening protection measures for women victims of violence. The objective of this research is to understand the impact of these changes on the fight against domestic and family violence and on the protection of women. To this end, a bibliographic review was used as a methodology, complemented by a detailed analysis of the laws that modified the Maria da Penha Law. The relevance of this research lies in the need to evaluate legislative advances in addressing gender-based violence, a social problem deeply rooted in Brazilian culture. The research is justified by the urgency of analyzing the effectiveness of legislative changes, considering the social context and the importance of improving public policies aimed at protecting women. The results show that the main recent changes include improvements in police and forensic services, criminalization of non-compliance with emergency protective measures and increased enforcement of the law, regardless of the condition or motivation of those involved.
EFEITOS DAS ALTERAÇÕES RECENTES NO ESTATUTO DO DESARMAMENTO: UMA ANÁLISE DAS IMPLICAÇÕES PARA A SEGURANÇA PÚBLICA NO BRASIL
Authors: Lima Paulo Rolon de
Published: October 2024

This research addresses recent changes to the Disarmament Statute in Brazil and their implications for public safety. The Disarmament Statute, established by Law No. 10.826/2003, was created to reduce the circulation of firearms in the country and reduce violence rates. However, in recent decades, significant changes in legislation have made access to weapons more flexible, sparking debates about the possible impacts of these changes on the security and crime scenario. The relevance of the research lies in the fact that gun control is a central issue for public safety, being widely discussed in various political and social contexts. Thus, the research is justified by the need to understand the possible effects of changes to the Disarmament Statute, considering the increased flexibility of access to weapons. The main objective of this research was to analyze these recent changes to the Disarmament Statute and evaluate their effects on the regulation of access to weapons and on violence and crime rates in Brazil. To achieve this objective, the methodology adopted was based on a bibliographic review and analysis of laws related to the topic. The results of this research showed that recent changes to the Disarmament Statute have the potential to significantly impact public safety in Brazil. The analysis of the legislative changes revealed that, with the relaxation of access to and possession of weapons, there is an increased risk of weapons circulating in the hands of the civilian population, which can aggravate situations of violence and crime.
The role of microenvironmental factors in the pre-ovulatory oocyte in the pathogenesis of “poor” ovarian response to in vitro fertilization (IVF) programs
Authors: Dzhalilova E. R. , Bashmakova N. V. , Gazieva I. A. , Chistyakova G. N. , Pestryaeva L. A.
Published: October 2024

Background. The “poor” response to ovarian stimulation during IVF (in vitro fertilization) cycles depends on various factors, including the biochemical composition of the follicle microenvironment. Recent studies have focused on the relationship between vascular tone regulators, angiogenic factors, oxidative stress, and the quality of oocytes. Despite this, there is still no consensus on the exact eﬀect of these factors on folliculogenesis or their role in “poor” responses.

Objective. To evaluate the content of biochemical factors and regulators of vascular tone and angiogenesis in follicular fluid in patients with a “poor” ovarian response to stimulation in IVF programs, compared to similar indicators in women with a normal ovarian response.

Materials and methods. An open prospective cohort study was conducted, including 56 patients who were part of the IVF program. The criterion for separating the cohort of women was their response to controlled ovarian stimulation during the IVF cycle. Women with a “poor” response (n=32) were placed in the main group, while those with a normal response (n=24) were in the comparison group. Follicular fluid samples from women with a “poor” response were divided into two subgroups based on the presence or absence of an oocyte-cumulus complex in the follicle. The biochemical and soluble regulatory factors in follicular fluid were analyzed in both groups after controlled ovarian stimulation was completed. Statistical analysis of the data was done using methods from variation statistics. A critical level of significance for the diﬀerences was set at p ≤0.05.

Result. The levels of urea, glucose, high-density lipoprotein, and total antioxidant status (TAOS) in follicular fluid (FF) from patients with a “poor” ovarian response were statistically significantly higher compared to those in the control group. The levels of bilirubin, low-density lipoprotein, and uric acid were also significantly lower in VF from patients in the main group compared to the control group, p<0.05. The indices of vascular endothelial growth factor (VEGF-A) and vascular endothelial growth receptor-2 (VEGFR-2) in FF from women with a “poor” response were significantly lower than those from patients with a normal response, while the levels of endogenous nitric oxide were significantly higher in the former group compared to the latter, p<0.05.

Conclusion. The absence of an oocyte-cumulus complex in the pre-ovulatory follicle, which is associated with a “poor” response of the ovary to stimulation, is likely due to a disruption in vascularization processes. This is supported by a decrease in the levels of pro- and anti-angiogenic factors, such as VEGF-A and VEGFR-2.
Morphological verification of the effects of dynamic quadripolar radio frequency in patients of reproductive age with pelvic organ prolapse
Authors: Iuminova A. V. , Mikhelson A. A. , Lazukina M. V. , Chistyakova G. N. , Grishkina A. A.
Published: October 2024

Background. Pelvic organ prolapse is a common pathology that has a significant impact on women’s quality of life. According to literature data, 30% of women of reproductive age have symptomatic forms of pelvic organ prolapse (POP). 13% of patients undergo surgical treatment of POP. However, some patients again complain about the symptoms of genital prolapse, despite the surgical correction.

Objective. To evaluate the eﬀect of dynamic quadripolar radio frequency on the histological picture of the vaginal mucosa in patients of reproductive age with pelvic organ prolapse.

Materials and methods. A prospective comparative study was conducted, which included 38 patients of reproductive age. The patients were randomized and divided into 2 groups 2 months before the surgical treatment of POP. The first group (n=17) of patients underwent preoperative preparation using dynamic quadripolar radio frequency (DQRF) before surgical treatment. The second group (n=21) did not undergo preoperative preparation. Both groups of women received surgical treatment in volume — plastic surgery of genital prolapse with their own tissues. A biopsy of the vaginal mucosa was obtained intraoperatively, and its histological assessment was performed. The material was stained with hematoxylin-eosin, light microscopy was performed using an Axioplan 2 microscope (CarlZeissJena, Germany).

Results. Increased vascularization of the vaginal mucosa, absence of signs of inflammation and fibrosis, and ordering of collagen bundles were noted in patients who underwent preoperative preparation using DQRF.

Conclusion. Changes in the histological picture of the vaginal mucosa after the use of DQRF indicate an increased regenerative ability of tissues, which may be a predictor of better healing after surgical treatment and may aﬀect the long-term results of surgical treatment.
Modern view on predicting outcomes after fetoscopic laser coagulation of placental anastomoses in polyuria-oliguria syndrome (review)
Authors: Pospelova Ya. Yu. , Kosovtsova N. V.
Published: October 2024

The purpose of this literature review is to analyze the results of fetoscopic laser photocoagulation of placental anastomoses, obtained in various studies published in foreign and domestic medical publications in recent years.

Materials and methods. The review included published data over the last 10 years. The literature search was conducted in Medline, Scopus, Web of Science, Google Scholar, PubMed, Wiley and Cochrane Library databases.

Result. As a result of the analysis, the main ultrasound and fetoscopic markers influencing the outcome of the surgical treatment were determined: the location of the placenta on the anterior and posterior walls, the location of the umbilical cord attachment, the number of placental anastomoses; abnormal graphs of blood flow rates in the umbilical cord arteries; the distance between the attachment points of the umbilical cord; dissociated growth of the fetuses; the duration of gestation and the stage of severity of twin-to-twin transfusion syndrome, as measured with the R. Quintero staging system, at the time of the operation; the experience of the operating surgeons; and the duration of the operation.

Conclusion. Analysis of the literature data has shown that these markers are extremely unreliable in predicting the chances of survival for one or both fetuses. Further study of ultra-sound and fetoscopy predictors of adverse outcome of laser photocoagulation of placental anastomoses will allow for a more balanced approach to the choice of surgical tactics and personalized consultations with patients.
Modern aspects of preimplantation genetic testing of embryos in assisted reproductive technology programs (literature review)
Authors: Bashmakova N. V. , Khramtsova A. Yu. , Danishevskaya A. A.
Published: October 2024

Background. The success of assisted reproductive technologies depends on many factors, the main ones being the quality and genetic status of the embryo and endometrial receptivity. Preimplantation genetic testing is a tool that aims to reduce the risk of selecting an aneuploid embryo for transfer. Disputes surrounding the use of preimplantation genetic testing are conducted in the context of older patients, with recurrent miscarriage, with genetic karyotype abnormalities in a married couple, as well as multiple unsuccessful attempts at ART in the anamnesis.

Purpose of review. To summarize and analyze the available data on current trends in the use of preimplantation genetic testing (PGT-A).

Materials and methods. The review includes published data over the past 10 years regarding the eﬀectiveness of ART programs and pregnancy outcomes after the use of preimplantation genetic testing. The literature search was conducted in Medline, Scopus, Web of Science, Google Scholar, PubMed, Wiley and Cochrane Library databases.

Results. According to most authors, preimplantation genetic testing does not improve live birth rates per patient in the general population, but it does improve live birth rates when performing PGT-A on blastocyst-stage embryos in women over 35 years of age, as well as in women with a history of pregnancy loss to reduce risk miscarriage of a subsequent pregnancy.

Conclusion. Preimplantation genetic testing is a valid method for assessing euploidy and mosaicism of an embryo before transfer. The feasibility of use, according to research results, is more related to conditions in which the risk of embryonic aneuploidy may increase, and is justified in high-risk patients, while the use of this technique in patients with a good prognosis is still questionable. First, trophectoderm biopsies may not reflect the ploidy of the inner cell mass. Secondly, even if we assume that this is the case, we cannot be sure that the embryonic cell line will not self-correct. In other words, once a diagnosis of PGT-A is received suggesting mosaicism or aneuploidy, the likelihood of a false-positive diagnosis is high.
الاستمالات الإقناعية في الإعلانات التجارية لدى المؤثرين على شبكات التواصل الاجتماعي ودورها في تسويق المنتجات لدى الشباب الجامعي الأردني
Authors:   Mohammad O.  Shorman, Najadat Prof. Ali
Published: October 2024

Persuasions Grooming' in Commercial Advertisements Among the Influencers on Social Media and Their Role in Marketing Products Among the University Jordanian Youth The study aimed to identify the habits and patterns of university Jordanian youth’s exposure to advertisements presented by Social Media Influencers and their confidence in them and the persuasion techniques they contain. This study is classified as descriptive-analytical research, which relied on the survey methodology, where the sample of the study consisted of (393) items from the study community, represented by the students of Yarmouk University and Jadara University in the northern part of Jordan, who use social networks and follow the advertisements of influencers on them. To achieve the study's objectives, the researchers relied on the questionnaire as a data collection tool. The study found that the degree of university Jordanian youth’s follow-up to Social Media Influencers and their follow-up to commercial advertisements presented by them was (Medium), it also showed that the degree of university Jordanian youth’s confidence in commercial advertisements presented by influencers was also (Medium). The study showed that psychological persuasion ranked first as the most prominent persuasion that works to attract university youth to the advertisements presented by Social Media Influencers. The study also found that the most prominent factor that drives university Jordanian youth to pay attention to commercial advertisements presented by influencers is the influencer himself, followed by the way the advertisements are presented. It revealed a significant direct correlation between the extent to which university youth trust commercial advertisements submitted by Social Media Influencers and the extent to which they respond to advertisements submitted by them in terms of purchasing the product or not.
Poésie et musique à la Renaissance
Authors: Millet Olivier , Tacaille Alice
Published: October 2024

À l’heure où un volume croissant de sources et d’instruments de recherche renouvelle notre connaissance de la culture poético-musicale de la Renaissance, les savoirs littéraires et musicologiques ont tout intérêt à croiser leurs regards sur un objet commun, la poésie chantée. C’est ici dans la plus grande diversité de leurs aspects et de leurs manifestations que les relations entre poésie et musique sont examinées, dans le cas de la France, sur l’ensemble d’un siècle brillant et inventif.

Comme ces objets particuliers, le livre de poésie à chanter, le recueil de chansons, de chansons musicales ou de cantiques, portent-ils, à partir de Marot et parallèlement à la diffusion manuscrite, une ambition sonore nouvelle au début de l’époque moderne, et quel rôle cette part sonore peut-elle jouer dans les évolutions successives des premières poétiques modernes ? Comment l’immense et polymorphe chantier de la langue française du XVIe siècle, dont se saisissent grammairiens, typographes et poètes, travaille-t-il les aspects les plus mécanisables des deux langues pour tenter de les faire coïncider « à plus haut sens », et au bénéfice de quels idéaux ? Comment ces plongées dans la matière sonore, qui absorbaient autant Du Bellay, Louise Labé, Ronsard ou Baïf, que Le Jeune, Goudimel, Janequin ou Muret, inspirent-elles d’abord, dans les années 1550, puis contribuent-elles ensuite aux ambitions harmoniques de la politique de Charles IX (création de l’Académie de musique et de poésie en 1570) ? Musiciens et poètes, sans toujours la formaliser de manière aussi volontariste que dans le cas des vers mesurés, mettent en œuvre une véritable approche commune du sonore poétique.
En vestjysk herredsskriver og hans baggrund
Authors: Bøggild-Andersen Boel
Published: October 2024

Inkluderer desuden yderligere litteratur anvist i "på dialekt om dialekt" på s. 30.
Response surface methodology for rapid removal of an azo dye methyl orange by indigenous bacterial strain (Bacillus cereus J4)
Authors: Rani Jyoti , Bera Surojit , Gaur Vinita , Singh Joginder , Goutam Umesh
Published: October 2024

Sulfonated azo dyes like Methyl Orange (MO) are widely used in industries such as textiles, paper, food, and printing, but their discharge into wastewater poses a serious threat to aquatic life. This study aimed to isolate and optimize bacterial strains for the bioremediation of MO from textile effluents. Eleven bacterial strains were isolated from industrial effluents in Panipat, India, with Bacillus cereus J4 demonstrating the highest decolorization efficiency, removing up to 98% of MO within 48 hours. To optimize the decolorization process, two methods were employed Plackett–Burman (PB) design and Response Surface Methodology (RSM). PB design identified significant factors affecting decolorization, while RSM provided a more comprehensive optimization by considering interactions among factors. RSM reported an optimal removal rate of 89.8% MO at 50 mg/l dye concentration, pH 7, 37°C, and 2% urea. In conclusion, Bacillus cereus J4 showed promising potential for MO bioremediation under optimized conditions. Future studies should explore scaling up the process and examining the strain’s effectiveness on other industrial dyes to develop a broad-spectrum bioremediation strategy.
Ultra-high vacuum measurement based on 7Li cold atoms manipulation
Authors: Cheng Yong-Jun , Dong Meng , Sun Wen-Jun , Wu Xiang-Min , Zhang Ya-Fei , Jia Wen-Jie , Feng Cun , Zhang Rui-Fang ,   Science and Technology on Vacuum Technology and Physics State Key Laboratory, Lanzhou Institute of Physics, Lanzhou 730000, China
Published: October 2024

The redefinition of the International System of Units (SI) promotes the transformation of the vacuum measurement system toward quantization, and the quantization of vacuum parameters is one of the most leading, prospective and subversive research directions in the field of international vacuum metrology, and the quantum vacuum measurement is based on the quantum effect of the microscopic particle system, and the use of optical means and the theory of quantum mechanics to realize the precision measurement of the vacuum parameters. We develop a lithium-cooled atom vacuum measurement apparatus, which mainly consists of a 7Li atom trap system and a continuous expansion vacuum system. In this work, an experimental study of ultrahigh vacuum measurement is carried out by manipulating 7Li atoms and utilizing the loss characteristics of lithium cold atoms in magneto-optical and magnetic traps, and the results show that for the four commonly used gas molecules in vacuum, namely N2, Ar, He, and H2, in the vacuum range of (3×10–8–4×10–5) Pa, the maximum measurement uncertainty is 7.6%–6.0% (k = 2) based on 7Li cold atoms, and the cold atom vacuum measurement results are in good agreement with those of the traditional ionization vacuum gauges, and their relative sensitivities are in good agreement with those of the ionization vacuum gauges, and the maximal deviation of the relative sensitivity factor is less than 8%, which verifies the accuracy and reliability of the cold-atom quantum vacuum measurements. The research results are of great significance in promoting the development of new cross-generation vacuum measurement technology and meeting the needs of space science exploration, ultra-precision measurement and high-end equipment manufacturing.
Laser envelope control of strong field excited Rydberg states
Authors: Zhao Ling-Yi , Liu Jin-Lei , Jiang Tao , Lang Yue , Zhao Zeng-Xiu ,   College of Science, National University of Defense Technology, Changsha 410073, China,   Hunan Key Laboratory of Extreme Matter and Applications, National University of Defense Technology, Changsha 410073, China
Published: October 2024

Rydberg atoms are important building blocks for quantum technologies, and because of their unique tunable quantum properties, they possess new applications in quantum computing, quantum communication, and quantum sensing. Besides the widely-used few-photon resonant excitation for the specific Rydberg state, multiple Rydberg states can be populated coherently and efficiently through the frustrated tunneling ionization or the Coulomb potential recapture effect in a strong laser field. The excitation of Rydberg states in a strong field provides an opportunity for realizing the ultrafast quantum control on Rydberg atom and bridging the gap between strong field physics and quantum information technology. Using the classical trajectory Monte Carlo method and Qprop package to solve time-dependent Schrödinger equation, we calculate the population of Rydberg states. Our results show that the population increases with the increase of parameter of the asymmetric laser envelope. Based on the quantitative rescattering theory, the calculated time-dependent recapture rate is negatively related to the laser envelope and the residual laser interaction time, which is termed the envelope effect. Combined with the carrier-wave effect, an analytic formula can be used to calculate the Rydberg state population: \begin{document}$ Y(t) \propto $\end{document}\begin{document}$ W_0\left(t\right) \dfrac{t-\tau+c}{f\left(t\right)} \cos \left(\omega t+\phi\right) . $\end{document} This result opens the way to enhancing the generation of Rydberg states by using the laser envelope control, which is beneficial to the future quantum technology based on the Rydberg states generated in the strong laser field.
Stability analysis of Fermi-Pasta-Ulam-Tsingou phenomenon in nonlinear optical fibers
Authors: Hu Zhi , Li Jin-Hua , Li Meng-Meng , Ma You-Qiao , Ren Hai-Dong ,   School of Mathematics and Physics, Anhui Jianzhu University, Hefei 230601, China,   School of Physics and Optoelectronic Engineering, Nanjing University of Information Science & Technology, Nanjing 210044, China,   State Key Laboratory Cultivation Base of Atmospheric Optoelectronic Detection and Information Fusion, Nanjing University of Information Science & Technology, Nanjing 210044, China,   Xiamen Xiang Fu Xing Technology Co., Ltd., Xiamen 361000, China
Published: October 2024

Stability plays a significant role in successfully observing Fermi-Pasta-Ulam-Tsingou (FPUT) phenomenon in experiment. However, there are few relevant studies in the literature. The primary object of this work is to study the stability of FPUT phenomenon in the nonlinear fibers numerically. In this study, we take the sinusoidally perturbed continuous waves (CWs) with white noise as the imposed initial condition, which can be readily realized in real experiments. We find that both the perturbation amplitude and phase difference between the perturbation and pump can drastically affect the stability of the resulting FPUT phenomenon. Firstly, as the perturbation amplitude increases, the FPUT phenomenon becomes much more stable. When the perturbation amplitude reaches a critical value, the most stable FPUT phenomenon can be observed. With the further increase of the perturbation amplitude, the stability of the resulting FPUT phenomenon weakens. Secondly, the phase difference between the perturbation and pump takes distinct effects on the stability of FPUT phenomenon for perturbation frequency located inside and outside the conventional modulation instability (MI) band. For the perturbation frequency located inside the conventional MI band, as the phase difference between the perturbation and pump increases from zero, the corresponding FPUT phenomenon first is less stable, and then becomes most instable at a critical phase difference; after that, the stability of the FPUT phenomenon is enhanced again. For the perturbation frequency located outside the conventional MI band, the stability of FPUT phenomenon is enhanced monotonically as the phase difference increases from 0 to π/2.

In order to observe a much more stable FPUT phenomenon, as shown in the above results, the perturbation amplitude should be moderately large, and the phase difference between the perturbation and the pump should be appropriate to avoid the most instable FPUT phenomenon.
Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity
Authors: Yu Hong , Nishio Hiroshi , Barbi Joseph , Mitchell-Flack Marisa , Vignali Paolo DA , Zheng Ying , Lebid Andriana , Chang Kwang-Yu , Fu Juan , Higgins Makenzie , Huang Ching-Tai , Zhang Xuehong , Li Zhiguang , Blosser Lee , Tam Ada , Drake Charles G , Pardoll Drew M
Published: October 2024

The adaptive T cell response is accompanied by continuous rewiring of the T cell’s electric and metabolic state. Ion channels and nutrient transporters integrate bioelectric and biochemical signals from the environment, setting cellular electric and metabolic states. Divergent electric and metabolic states contribute to T cell immunity or tolerance. Here, we report that neuritin (Nrn1) contributes to tolerance development by modulating regulatory and effector T cell function. Nrn1 expression in regulatory T cells promotes its expansion and suppression function, while expression in the T effector cell dampens its inflammatory response. Nrn1 deficiency causes dysregulation of ion channel and nutrient transporter expression in Treg and effector T cells, resulting in divergent metabolic outcomes and impacting autoimmune disease progression and recovery. These findings identify a novel immune function of the neurotrophic factor Nrn1 in regulating the T cell metabolic state in a cell context-dependent manner and modulating the outcome of an immune response.
Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity
Authors: So Jisun , Strobel Olivia , Wann Jamie , Kim Kyungchan , Paul Avishek , Acri Dominic J , Dabin Luke C , Peng Gang , Kim Jungsu , Roh Hyun Cheol
Published: October 2024

Single nucleus RNA sequencing (snRNA-seq), an alternative to single cell RNA sequencing (scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA, persistently hindering its applications. Here, we present a robust technique for isolating nuclei across various tissue types, remarkably enhancing snRNA-seq data quality. Employing this approach, we comprehensively characterize the depot-dependent cellular dynamics of various cell types underlying adipose tissue remodeling during obesity. By integrating bulk nuclear RNA-seq from adipocyte nuclei of different sizes, we identify distinct adipocyte subpopulations categorized by size and functionality. These subpopulations follow two divergent trajectories, adaptive and pathological, with their prevalence varying by depot. Specifically, we identify a key molecular feature of dysfunctional hypertrophic adipocytes, a global shutdown in gene expression, along with elevated stress and inflammatory responses. Furthermore, our differential gene expression analysis reveals distinct contributions of adipocyte subpopulations to the overall pathophysiology of adipose tissue. Our study establishes a robust snRNA-seq method, providing novel insights into the biological processes involved in adipose tissue remodeling during obesity, with broader applicability across diverse biological systems.
Clinico-Radiological Manifestations of Cochlear Schwannomas
Authors: Hashim Noor Dina , Misron Khairunnisak , Moon Seo Jin , Noh Hae Eun , Kim Jinna , Moon In Seok
Published: October 2024

Background and Objectives: Cochlear schwannomas, which are categorized into intracochlear and intravestibulocochlear schwannomas (ICs and IVCs, respectively) are rare and may cause hearing loss (HL). The affected region is invariably correlated with tumor location, which can be detected on magnetic resonance imaging (MRI). We describe the cochleovestibular manifestations of ICs and IVCs. Subjects and Methods: The study included 31 patients with ICs or IVCs. Tumor extent and exact locations were delineated using MRI. Types of HL were subcategorized into the low-to-mid frequency (250 Hz to 1 kHz), mid-to-high frequency (>1 kHz), and all-frequency (universal) HL groups. Results: The tumors involved the entire cochlear turn (two ICs) or extended beyond the cochleae (nine IVCs) in 11 patients, and 20 ICs were located in specific locations as follows: 14 in the basal, 3 in the middle, and 3 in the middle and apical turns. No patient showed tumor invasion of the internal auditory canal or middle ear. The pattern of HL usually reflects the location or extent of a tumor. We observed HL at all frequencies, at low-to-mid frequencies, and at mid-to-high frequencies in 13, 4, and 14 patients, respectively. Dizziness or tinnitus was observed in >50% of patients. Surgical tumor removal was performed in 10 patients, and the remaining patients are undergoing annual monitoring. Conclusions: Cochlear schwannomas may be associated with HL, which may worsen over time and reflect tumor location. Therefore, these lesions should be considered in the differential diagnosis in patients who present with idiopathic, fluctuating, progressive or sudden HL.