bluuebunny/crossref_metadata_2025 huggingface dataset:
Fetomaternal outcome in pregnancies complicated by fibroid
Authors: Singh Leimapokpam Roshan , Mahajan Kaushik , Singh Nandeibam Balchand , Singh Wairokpam Prabinkumar , Athokpam Kabita , Jinaluxmi R. K.
Published: July 2021

Background: Fibromyoma (leiomyoma) is the most common benign tumour of the uterus. Approximately 10% to 30% of women with uterine fibroids developed complications during pregnancy. The aim of the study was planned to ascertain the fetomaternal outcome in pregnancies complicated by fibroid.Methods: A hospital based cross-sectional study was conducted among pregnant women with documented uterine fibroid who was admitted for any complication or delivered in the department of obstetrics and gynaecology, RIMS, Imphal from September 2017 to August, 2019 in the department of obstetrics and gynaecology in collaboration with department of paediatrics, Regional institute of Medical Sciences, Imphal. Detailed clinical history and socio-demographic profile were recorded in pre-designed proforma. General physical examination and systemic examination and obstetrical examination was carried out for the participants.Results: Major proportions was in the age group of 30-39 years (73.9%). Fibroids were more frequent in primigravida (76.1%) followed by P1 (15.2%) and ≥P2 (8.7%). Out of 46 patients 43 (93.5%) delivered by CS (69.76%), NVD (25.58%) and instrumental delivery (4.65%) while 3 patients (6.5%) undergo spontaneous abortions. Most common myoma found in this study was intramural (47.8%) followed by submucous (34.8%) and subserosal (17.4%). Out of 43 deliveries most common complications found was atonic PPH (6.97%) and placenta previa (6.97%) followed by degenerations (2.32%), abruptio placentae (2.32%), malpresentations (2.32%). Out of 43 deliveries 6.9% baby born with low birth weight, IUGR (6.9%), IUFD (4.6%), NICU admission (4.65%) and early neonatal death (2.32%).Conclusions: Pregnancies with fibroids are considered as high-risk pregnancy associated with complications during the antepartum, intrapartum, postpartum period. Pregnant women with myoma can be advised for regular ANC along with TAS for early diagnosis and management of complication.
Meta-analysis on maternal deaths and assessing significant factors for heterogeneity between states of India during 2016
Authors: Perumal Vanamail
Published: July 2021

Objective of the study was to provide a more precise estimate of maternal mortality (MM), maternal mortality ratio (MMR) and to identify significant factors contributing for heterogeneity between the states in India. “Metaprop” procedure in STATA software, which are specific to binomial data was applied on state wise MM data published by sample registration system (SRS) during 2014-16. An overall MM estimate and potential sources of heterogeneity could be identified using meta-regression. Corrected estimates of MMR by states were compared. SRS published the MM data by 17 Major states. Overall reported MM was 8.8 per 100, 000 women. Estimate obtained by random effect model was 8.3 (95% CI: 5.9-11.1) per 100,000 women. Heterogeneity between states was very high (I2-statistics =91.9%), and egger regression revealed no reporting bias (p=0.672). Meta-regression analysis indicated that the percent women attending full antenatal care (ANC) visits found to be highly significant (p<0.001) for MM with inverse relationship implying that the states with a higher percentage of women with full ANC visits are likely to have lesser MM. While the estimate of MMR by SRS was 130 per 100,000 live births, corrected MMR was 123 (95% CI: 87-164) accounting for 26% reduction from previous estimate 167 obtained in 2013. This paper provided a precious estimate of both MM and MMR adjusted for sampling weight. Further, the importance of either full ANC visits or four ANC visits could be demonstrated for reduction in MMR on achieving the Millennium development goal (MDG) in the country.
Maternal and perinatal outcome in rupture of unscarred uterus: a case series
Authors: Kurian Ancy M. , Roy Indrani , Saikia Neelotparna , Mihsill Kerlin
Published: July 2021

Uterine rupture is one of the main contributory factors of maternal morbidity and fetal mortality. The aim of this study was to study the maternal and perinatal outcome in rupture of unscarred uterus and to identify the etiology, risk factors, diagnosis and management in a tertiary care centre. This case series study was often cases of rupture of unscarred uterus conducted at the department of obstetrics and gynecology, Nazareth hospital, Shillong, Meghalaya from July 2018 to February 2021. During the study period there were 7840 deliveries and ten patients presented with rupture of unscarred uterus, the incidence being 0.127 %. The patients were referred from different primary health centres and all patients presented with history of trial of home delivery. All patients were multigravida and the highest parity was a patient with para 11. The cases were between the gestational age of 39 to 41 weeks. Rupture was observed in the lower uterine segment in 5 patients, left lateral wall in 3 and right lateral wall in 2 patients. Five patients underwent hysterectomy, and 4 patients had repair of the rupture. There was one maternal death. Grand multipara and trial of home delivery were the most common identifiable risk factors along with obstructed labour. Identifying high risk women, prompt diagnosis, early referral from periphery and active management is the key factor to avoid adverse maternal and perinatal outcome.
An interesting case of intrauterine torsion of ovarian cyst in a female fetus
Authors: Barla Jaya , Nayak Vaishali K. , Patil Kalpesh
Published: July 2021

Fetal ovarian cysts are usually benign and managed conservatively. We report an interesting case of fetal ovarian cyst diagnosed in the antenatal period. Post-delivery, neonate was operated for torsion of the ovarian cyst. The baby recovered well.
Endometrioma mimicking ovarian malignancy in a post-menopausal woman
Authors: Zutshi Vijay , Gupta Shreshtha , Ahluwalia Charanjeet , R. Monica
Published: July 2021

Endometriosis is an estrogen dependant disorder of reproductive-age women. It is uncommon after menopause, however, peripheral estrogen production may account for endometriosis in post-menopausal women. We reported a case of a 68 year old post-menopausal woman with an adnexal mass suspected malignant ovarian tumor on imaging and normal serum CA 125 levels. Total hysterectomy with bilateral salpingo-oophorectomy was done. The final histopathology revealed the diagnosis of ovarian endometriosis. Rarely, ovarian endometrioma can mimic ovarian malignancy in a post-menopausal woman.
Bleeding abdominal scar endometriosis-a case report
Authors: Das Badal , Sarkar Malay , Roy Debobroto , Das Krishna Pada , Khatun Nazmin , Moulick Aritrick
Published: July 2021

Presence of functional endometrial tissue anywhere outside the uterine mucosa is called endometriosis. It is hormone dependent and almost exclusively it affects the women of reproductive age. Abdominal scar endometriosis is a rare condition and it is due to deposition of endometriotic tissue in the wound site during various obstetric or gynecological operative procedures. Scar endometriosis followed by lower segment caesarean section (LSCS) is very rare and presents with co-menstrual pain and bleeding. Our case presented with active bleeding from abdominal LSCS scar during menstruation which is extremely a rare presentation. Wide excision and histo-pathological examination confirm the diagnosis. A 28-year-old lady with previous history of LSCS 2 years back presented with complaining of swelling and bleeding from the previous LSCS scar during menstruation, persisting for 4-5 days, repeatedly in every menstrual cycle for last 6 months. On examination a swelling with active bleeding from it was noted over the previous LSCS scar. Routine investigation and coagulation profile was with in normal limit and on ultrasonography a firm mass was noted. After wide excision and histo-pathological Examination, the diagnosis was confirmed. Co-menstrual swelling, pain and bleeding from the previous LSCS scar should not be neglected and may be due to scar endometriosis.
Optimized outcome of pregnancy in a woman with Glanzmann thrombasthenia with multidisciplinary approach
Authors: Radhakrishnan Sujithradevi , Dorairajan Gowri , Subbaiah Murali , Sharma Jyotsna
Published: July 2021

Glanzmann thrombasthenia (GT), an autosomal recessive disorder of defective platelet aggregation due to abnormalities of platelet receptor GPIIb/IIIa, can result in complication of bleeding during pregnancy. We report multidisciplinary management of a case with optimized outcome. 23 years old short statured (142 cm) primigravida was referred for contracted pelvis at term in labour. She was diagnosed with GT at 12 years of age during evaluation of gum bleeding, easy bruising, and prolonged post traumatic bleeding. She was born of a second-degree consanguineous marriage. At admission she was hemodynamically stable but moderately pale. Her hemoglobin was 8.7 g%, with 4.6 lacs platelets and clotting time of 15 minutes. Multidisciplinary team of hematologist, transfusionist and anesthetist was activated. Arranging single donor platelets in a short notice was challenging. Emergency cesarean section under general anesthesia was performed after transfusing two units packed red blood cell and 2 single donor platelets to deliver an alive male baby of 3.3 kg. Hemostasis was secured with cautery and ligatures. Tranexamic acid infusion and sublingual misoprostol was given prophylactically. she was transfused another 4 random donor platelets during operation and postoperatively. The case details will be presented. GT have normal to high platelet counts though they are normal morphologically, they are dysfunctional. This fact needs to be recognized and referred early to equipped centres. We used component transfusion, active management of third stage and tranexamic acid for optimizing outcome due to haemorrhage. At present, there is lack of consensus regarding optimum treatment of post-partum hemorrhage in patients with GT.
A case of placenta increta in placenta previa: a rare case report
Authors: Das Badal , Roy Debobroto , Sarkar Malay , Das Krishna Pada , Khatun Nazmin , Moulick Aritrick
Published: July 2021

Placenta increta, one type of morbidly adherent placenta, is characterized by entire or partial absence of the decidua basalis, and by the incomplete development of the fibrinoid or Nitabuch’s layer and villi actually invading the myometrium. When the internal os is covered partially or completely by placenta, it is described as a placenta previa. Simultaneously these two complications occurring in a post LSCS scarred uterus is a very rare scenario and anticipated frequently to cause catastrophic obstetric outcome. A 32-years-old woman of second gravida, para 1, with previous history of LSCS 7 years back, with living issue one, admitted in our hospital at 35 weeks 5 days gestation with asymptomatic placenta previa with placenta increta. The case was diagnosed effectively by ultrasonography. Intra-operatively, compression sutures and bilateral uterine artery ligature was tried to control hemorrhage which were failed and a quick decision of caesarean hysterectomy was done. Preserving both ovaries, total hysterectomy was the only option to save the mother in our case. Other options attempting to preserve uterus could have ended up with grave consequences in this case. This was a very rare case of asymptomatic placenta previa with placenta increta in a post LSCS scarred uterus and it was successfully managed by judicious caesarean hysterectomy.
Changing trends in the management of corpus luteum haemorrhage
Authors: Gupta Avantika , Nayak Deepthi , Tiwari Purnima
Published: July 2021

Corpus luteal haemorrhage usually causes only mild symptoms and resolve spontaneously, however, it can cause massive bleeding in certain patients with coagulation or bleeding disorders. Over a decade, the management of corpus luteum haemorrhage has shifted from surgical to conservative management. This article focuses on selection of patients for conservative management so that the morbidities associated with the surgery can be avoided. Conservative management includes optimization of oxygen carrying capacity of blood, correction of coagulopathy and appropriate analgesia. It can be recurrent in certain high-risk group of patients who will need long term suppression of ovulation.
DOS MERCADOS MEDIEVAIS AOS SHOPPING CENTERS: UM ESTUDO SOBRE AS DINÂMICAS TERRITORIAIS DO EMPRESÁRIO DO COMÉRCIO
Authors: Santos Clenio Ricardo Fonseca , Nonato Eunice Maria Nazarethe
Published: July 2021

O presente artigo busca apresentar as dinâmicas territoriais da microempresa, pessoa jurídica de considerável importância no desenvolvimento da economia brasileira, pela sua atuação em shopping centers, ambientes que agregam lazer e serviços ao comércio, com o objetivo de atrair pessoas para mais consumir e gerar mais receita. A existência dessa forma de exercício da atividade comercial, os shopping centers, decorre do surgimento dos halles, os mercados localizados nas praças locais das primeiras cidades europeias destinados à troca de mercadorias e interação de comunidades distantes, vindo esse espaço de troca de mercadorias e venda dos excessos de produção a se constituir no ápice do consumo, o que culmina com o desenvolvimento de uma nova territorialidade do empresário do comércio nesse local.
Medicinal plants used in cosmetics for skin and hair care
Authors: Tamboli Firoj A , Kolekar Yogesh S , More Harinath N , Mulani Sajid A , Mali Nitin P
Published: July 2021

This study aimed at reviewing the importance of medicinal plants for the treatment of common hair problems such as baldness, alopecis hair fall, gray hair, dryness and most comman drandruff. The various herbal ingredient are used in the formation are Aloe, Amla, Curry leaves, Camphore, Coconut oil, Eclipta alba, Hibiscus, Heena, Neem, Fenugreek, Sage, Apamarg, Onion, grape seeds, Jatamanshi, Rosamary, Thyme, Tulsi, Garlic and Neem. All ingredients provide essential nutrients such as Vitamin, terpenoids and many essential oils to maintain normal function of sebaceous gland and overall care of skin and hair.
Chemical classification of MDM2 inhibitors
Authors: Gohil Chirag J , Noolvi Malleshappa N , Patel Chhaganbhai N , Sen Dhrubo Jyoti
Published: July 2021

MDM2 inhibitors class of anti-neoplastic drugs has been evolve after the successful discovery of the nutlins and other potent inhibitors. MDM2 inhibitors can specifically target the tumour cells in the body, by selectively reactivating the inhibited p53 function in the tumour cells.

None of the compound of this class has been entered into the market till date, all are under clinical trials. Hence, various researcher classifies them according to their p53 topology mimetic property and as per their peptide type or non-peptide type.

Synthetic peptide type of inhibitors can mimic the conformation of p53 helix. Whereas, small organic molecule (non-peptide) type of MDM2 inhibitors have been further subdivided as Non α-helix mimetics (small molecule inhibitors) and α-helix mimetics.

In a line with synthetic inhibitors, many potent MDM2 inhibitors are derived from the natural origin (marine, fungus). Therefore, keeping in a view of all these characteristics, here we have classified them as per best of our knowledge.
Development of gastroretentiv floating tablets of losartan potassium by sublimation method
Authors: Bhusara Hiral S , Patel Ara T , Patel Mayuree D
Published: July 2021

The purpose of present study was to formulate and Evaluate Sustained release floating tablet of losartan Potassium using Camphor and Polyethylene Oxide as Pore formation for floating and release retarding agent respectively to improve gastric residence time and patient compliance in management of hypertension. The tablet was prepared by direct compression by using HPMC K4 as dry binder. Camphor and PEO as floating and release retarding agent for sustained release floating tablet. Post compression was done to increase the hardness and floating time of tablet. Release modifier was used to speed up the release of drug from sustained release floating tablet. The effect of two independent variables like amount of Sublimating agent (camphor) and amount of Polyethylene oxide (PEO) on Q30min, Q360min, and Q720min was optimized using 32 factorial design and analyzed using the software design expert 10.0.3. The observed (actual values) responses were coincided well with the predicted values, given by the optimization technique. The floating tablet were characterized by FTIR for drug excipient compatibility.
Study on prevalence of obesity in urban and rural adolescents in Odisha: Implications for public health strategies
Authors: Kar Manoj , Behera Sasmita
Published: July 2021

Obesity and overweight have become a worldwide public health challenge and there is an urgent need to examine prevalence of obesity among adolescents. The aim of the present research is to determine health status with respect to obesity of urban & rural adolescents. The data were derived from cross-sectional sampling of adolescent boys and girls of urban and rural population. Age, gender and body mass Index was used to define overweight and obesity. The overweight and obesity were considered using an updated body mass index reference based on the revised consensus guidelines for India. It is observed that the average height and weight, physical growth of adolescents of urban area is greater than that of rural area irrespective of their gender. The BMI (Body Mass Index) of urban adolescents are more than their counterparts in rural area, but the mean BMI of rural and urban adolescents are significantly different. On the other hand BMI do not show any variation due to gender, area and gender considered together. Most of the adolescents irrespective of their area of residence, in spite of their long hours of sedentary behavior are falling under normal category.

The result showed physical activities did influence change in BMI, which has a strong independent association with family history of obesity in both rural and urban adolescents. This study analysis showed an increase in prevalence of overweight and obesity in urban adolescents especially with male gender, calling for an urgent need for targeted preventive measures targeting undernutrition and overweight involving public health nutrition interventions for healthy public policies and implementation of equitable nutrition interventions for optimizing public health outcomes for those populations in greater need.
State of the Climate Report: Suriname: Summary for Policy Makers
Authors: Solaun Kepa , Resomardono Chiquita , Hess Katharina , Antich Helena , Alleng Gerard , Flores Adrián
Published: July 2021

Several factors contribute to Surinames particular vulnerability to the effects of climate change. It is dependent on fossil fuels, has forests liable to decay, fragile ecosystems, and its low-lying coastal area accounts for 87% of the population and most of the countrys economic activity. Many sectors are at risk of suffering losses and damage caused by gradual changes and extreme events related to climate change. For Suriname to develop sustainably, it should incorporate climate change and its effects into its decision-making process based on scientific- evidence. The State of the Climate Report analyzes Surinames historical climate (1990-2014) and provides climate projections for three time horizons (2020-2044, 2045-2069, 2070-2094) through two emissions scenarios (intermediate/ SSP2-4.5 and severe/ SSP5-8.5). The analysis focuses on changes in sea level, temperature, precipitation, relative humidity, and winds for the seven subnational locations of Paramaribo, Albina, Bigi Pan MUMA, Brokopondo, Kwamalasamutu, Tafelberg Natural Reserve, and Upper Tapanahony. The Report also analyzes climate risk for the countrys ten districts by examining the factors which increase their exposure and vulnerability on the four most important sectors affected by climate change: infrastructure, agriculture, water, and forestry, as well as examining the effects across the sectors. The State of the Climate provides essential inputs for Suriname to develop and update its climate change policies and targets. These policies and targets should serve as enablers for an adequate mainstreaming of climate change adaptation and resilience enhancement into day-to-day government operations.
EL HISPANISMO Y LA HISPANOFILIA: UNA PERSPECTIVA HISTÓRICA
Authors: Payne Stanley G.
Published: July 2021

Se plantea un análisis de la evolución del hispanismo como especialidad historiográfica, a partir de una definición básica del mismo para conocer las claves de dicha evolución desde el siglo XVIII. Se compara la escuela de hispanistas franceses con la amplitud de temas y perspectivas del hispanismo anglonorteamericano. Se realiza un estudio más detallado de las aportaciones de los hispanistas norteamericanos y se desglosan tanto los tópicos como los contenidos temáticos y diferentes visiones que se han realizado desde los Estados Unidos. Se plantean unas conclusiones con reflexiones que aspiran a ser provechosas para un mejor conocimiento del significado del hispanismo en la actualidad.
CALATRAVA LA VIEJA (CARRIÓN DE CALATRAVA, CIUDAD REAL) EN LAS POSTRIMERÍAS DE LA EDAD DEL BRONCE (CA. 1200-800 A.C.)
Authors: Naranjo Pedro Miguel
Published: July 2021

Las campañas arqueológicas llevadas a cabo en Calatrava la Vieja desde 1984 han sacado a la luz materiales de época protohistórica que revelan fases de ocupación previas a la fundación de la ciudad andalusí en el siglo VIII d. C. Entre los materiales exhumados se han seleccionado las cerámicas del Bronce Final, situadas cronológicamente en función de la posición estratigráfica de estos materiales en los yacimientos circundantes. Esta etapa es, según la documentación disponible, la más antigua del yacimiento hasta la actualidad. Las formas registradas revelan una amplia red de contactos con otros ámbitos peninsulares en los que Calatrava jugó un papel destacado en el contexto del Alto Guadiana.
Escenarios sonoros del poder municipal en España durante la Edad Moderna: el caso de Jerez de la Frontera
Authors: Moreno Arana Juan Antonio
Published: July 2021

En el marco temporal que transita entre fines de la Edad Media y a lo largo de la Edad Moderna fructifica la progresiva integración de la música dentro de las prácticas sociales, ceremoniales y festivas que ponen en escena la imagen de las oligarquías urbanas. Este trabajo estudia la evolución de este fenómeno a partir de las completas fuentes documentales del Archivo Municipal de Jerez de la Frontera.
La altura de las estancias en el siglo XVIII en Burgos
Authors: Sanz de la Higuera Francisco José
Published: July 2021

Aunque, lamentablemente, no son muchos los datos disponibles en los memoriales del Catastro de Ensenada para la evaluación de la altura de las estancias de los interiores domésticos en las casas burgalesas del Setecientos, estas páginas nos acercan al análisis de dicha magnitud, en la medida de lo posible. El interrogante esencial deviene de la consideración de cuántos metros –“varas” en el XVIII– separaban los suelos de los techos en las habitaciones de las viviendas y el cómo se adaptaba la talla de los burgaleses a tal contraste constructivo.
Desiguales ante la muerte. Un estudio de caso en el Sur de España (1850-1950)
Authors: Luque de Haro Víctor A. , Sánchez Picón Andrés
Published: July 2021

El presente trabajo analiza las diferencias sociales en la mortalidad, poniendo en relación el desarrollo económico y las condiciones de vida de la población a partir del estudio de un caso: Vera, una localidad del sudeste español. La mayor parte de los datos se han extraído de censos de población y libros de defunciones parroquiales. La relación entre las tasas de mortalidad estandarizadas de cada uno de los grupos socioeconómicos ha sido el principal indicador utilizado para observar las diferencias en las condiciones de vida entre categorías ocupacionales. Los resultados muestran una progresiva reducción de la desigualdad social ante la muerte entre la población adulta desde el año 1860, momento en el que comienza nuestro análisis, hasta los años 30 del siglo XX. Este proceso de convergencia se trunca dramáticamente en los años de la posguerra. El comportamiento de la mortalidad desagregado por categorías socioeconómicas parece estar en línea con la evolución de los factores nutricionales y los relacionados con los avances higiénicos y en la salud pública.
Identification and validation of tumor microenvironment-related lncRNA prognostic signature for uveal melanoma
Authors:   Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China, Liao Chen-Lu , Sun Xing-Yu ,   Department of Gynecology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China, Zhou Qi ,   Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China, Tian Min ,   Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China, Cao Yang ,   Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China, Lyu Hong-Bin ,   Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Published: July 2021

AIM: To investigate the role of tumor microenvironment (TME)-related long non-coding RNA (lncRNA) in uveal melanoma (UM), probable prognostic signature and potential small molecule drugs using bioinformatics analysis.
METHODS: UM expression profile data were downloaded from the Cancer Genome Atlas (TCGA) and bioinformatics methods were used to find prognostic lncRNAs related to UM immune cell infiltration. The gene expression profile data of 80 TCGA specimens were analyzed using the single sample Gene Set Enrichment Analysis (ssGSEA) method, and the immune cell infiltration of a single specimen was evaluated. Finally, the specimens were divided into high and low infiltration groups. The differential expression between the two groups was analyzed using the R package ‘edgeR’. Univariate, multivariate and Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression analyses were performed to explore the prognostic value of TME-related lncRNAs. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional analyses were also performed. The Connectivity Map (CMap) data set was used to screen molecular drugs that may treat UM.
RESULTS: A total of 2393 differentially expressed genes were identified and met the criteria for the low and high immune cell infiltration groups. Univariate Cox analysis of lncRNA genes with differential expression identified 186 genes associated with prognosis. Eight prognostic markers of TME-included lncRNA genes were established as potentially independent prognostic elements. Among 269 differentially expressed lncRNAs, 69 were up-regulated and 200 were down-regulated. Univariate Cox regression analysis of the risk indicators and clinical characteristics of the 8 lncRNA gene constructs showed that age, TNM stage, tumor base diameter, and low and high risk indices had significant prognostic value. We screened the potential small-molecule drugs for UM, including W-13, AH-6809 and Imatinib.
CONCLUSION: The prognostic markers identified in this study are reliable biomarkers of UM. This study expands our current understanding of the role of TME-related lncRNAs in UM genesis, which may lay the foundations for future treatment of this disease.
Detection and Cooperative Communications for Deployment Sensor Networks
Authors: Benaissa Bedr-Eddine , Lahfa Fedoua , Naima Khatir , Lorenzini Giulio , Inc Mustafa , Menni Younes
Published: July 2021

In a sensor network, and more specifically with a single-hop deployment policy, sensor measurements contain a lot of redundancy either in the measurement dimensions of a single sensor, or between the measurement dimensions of different sensors due to of the spatial correlation either in the temporal dimension of the measurements. The goal is to reduce this redundancy by deploying fewer sensors, while ensuring high measurement accuracy and maximizing service life. The proposed method minimizes the complexity in terms of communication and calculation and maximizes the lifetime of the network based on an aggregation and consensus system to reduce the spatio-temporal dimension of the data captured and consequently the number of sensors deployed. The results show a visible performance compared to the standard method of transmission on the free platform of the COOJA/Contiki simulator allowing to simulate network connections of wireless sensors and to interact with them.
Gesture Recognition of Somatosensory Interactive Acupoint Massage Based on Image Feature Deep Learning Model
Authors: Jia Yukun , Ding Rongtao , Ren Wei , Shu Jianfeng , Jin Aixiang
Published: July 2021

During rehabilitation, many postoperative patients need to perform autonomous massage on time and on demand. Thus, this paper develops an individualized, intelligent, and independent rehabilitation training system for based on image feature deep learning model acupoint massage that excludes human factors. The system, which innovatively integrates massage gesture recognition with human pose recognition. It relies on the binocular depth camera Kinect DK and Google MediaPipe Holistic pipeline to collect the real-time image feature data on joints and gestures of the patient in autonomous massage. Then the system calculates the coordinates of each finger joint, and computes the human poses with VGG-16, a convolutional neural network (CNN); the calculated results are translated, and presented in a virtual reality (VR) model based on Unity 3D, aiming to guide the patient actions in autonomous massage. This is because the image feature of the gesture recognition and pose recognition is hindered, when the hand or the human is occluded by the body or other things, owing to the limited recognition range of the hardware. The experimental results show that, the proposed system could correctly recognize up to 84% of non-occluded gestures, and up to 93% of non-occluded poses; the system also exhibited a good real-time performance, a high operability, and a low cost. Facing the lack of medical staff, our system can effectively improve the life quality of patients.
A DWT Based Novel Multimodal Image Fusion Method
Authors: Panguluri Sumanth Kumar , Mohan Laavanya
Published: July 2021

Nowadays multimodal image fusion has been majorly utilized as an important processing tool in various image related applications. For capturing useful information different sensors have been developed. Mainly such sensors are infrared (IR) image sensor and visible (VI) image sensor. Fusing both these sensors provides better and accurate scene information. The major application areas where this fused image has been mostly used are military, surveillance, and remote sensing. For better identification of targets and to understand overall scene information, the fused image has to provide better contrast and more edge information. This paper introduces a novel multimodal image fusion method mainly for improving contrast and as well as edge information. Primary step of this algorithm is to resize source images. The 3×3 sharpen filter and morphology hat transform are applied separately on resized IR image and VI image. DWT transform has been used to produce "low-frequency" and "high-frequency" sub-bands. "Filters based mean-weighted fusion rule" and "Filters based max-weighted fusion rule" are newly introduced in this algorithm for combining "low-frequency" sub-bands and "high-frequency" sub-bands respectively. Fused image reconstruction is done with IDWT. Proposed method has outperformed and shown improved results in subjective manner and objectively than similar existing techniques.
An Approach of Detecting the Age of a Human by Extracting the Face Parts and Applying the Hierarchical Methods
Authors: Kathi Mohan Goud , Shaik Jakeer Hussain
Published: July 2021

One of the key challenges that the computer vision is facing is the age prediction. A well efficient CNN is selected for age prediction by performing various CNN operations by taking the categories as age 40 and above age 40. The selected CNN method obtained a training accuracy of 100% at more than 100 epochs. Hence, 100 epochs is considered for training. At this, the validation accuracy achieved is 84.9%. Three kinds of age phases with an age gap of 20,10 and 5 are used to predict the age. The normal method results in very less accuracy. Hence a hierarchical method is formulated. Under the hierarchical method, CNN is trained to estimate the age gaps in decreasing order. Hence not a single classifier, a group of classifiers are used for testing the image. From traditional method to hierarchical method, the 20 age gap accuracy increased from 27% to above 60%, ten age gap increased from 12% to above 35%, and five age gap increased from 5.5% to above 21%. To improve further, the features of the face parts are derived and combined which improves the efficiency compared to normal method, but not good accuracy as Hierarchical method. The combination of hierarchical method along with the face feature extraction method results in a considerable improvement in accuracy.
Contrast Enhancement of Poor-Quality Satellite Images Through Morphological Operations
Authors: Rao Gutta Srinivasa , Srikrishna Atluri
Published: July 2021

As a fruit of technological advancement, satellite images have been applied in many scientific fields, especially in surveillance. However, some satellite images are taken from an ultrahigh orbit in very dim situation. Data loss might occur due to the weak contrast between the dull pixels in such images, which cover a vast geographical area. Thus, it is necessary to improve the quality and contrast of satellite images. There are only a few techniques to improve the view and contrast of these images. To make matters worse, the contrast enhancement methods face many drawbacks. After estimating the brightness of each pixel, this paper integrates improved discrete wavelet transform (IDWT) with improved fuzzy C means clustering (IFCM) segment each poor-quality satellite image into multiple homogenous parts, and carries out morphological operations to enhance the contrast of the image. In addition, the proposed method was compared with traditional approaches. The results show that our method achieved the best performance in improving the quality of satellite images.
An Efficient Signal Processing Model for Malicious Signal Identification and Energy Consumption Reduction for Improving Data Transmission Rate
Authors: Alapati Yaswanth Kumar , Ravichandran Suban
Published: July 2021

One of the fields which needs the most security is Ad hoc Network (ANET). The term ANET guarantees that there is no central authority so as to administer the signals. Security is a basic issue while using ANET for establishing communication. A ANET is an assortment of remote signals that can progressively be set up at anyplace and whenever without utilizing any prior system framework. Because of its volatile nature, it has mobility issues to improve the arrangement of the system. One of the difficulties is to recognize the malicious signals in the system. Because of malicious signals, data loss or high energy consumption will occur which reduce the overall performance of the ANET. There are a few circumstances when at least one signal in the system become malevolent and will destroy the limit of the system. The point of this work is to recognize the malignant signals quickly to avoid loss of data. The conventional strategy for firewall and encryption isn't adequate to secure the system. In this way a malicious signal identification framework must be added to the ad hoc network. A signal needs to be secured when utilizing the resources and to provide secure communication. The ad hoc networks have several issues like, congestion, overload, data loss and energy consumption. In the proposed work a framework for Rapid Malicious Signal Detection with Energy Consumption Reduction (RMSDwECR) Method is proposed. The proposed method is compared with the traditional methods in terms of load in the network, data loss ratio, signal transmission rate, energy consumption levels, malicious signal identification time and throughput levels. The proposed method exhibits better performance than the traditional methods.
Jinwu Jiangu Capsule affects synovial cells in rheumatoid arthritis through PI3K/Akt/mTOR signaling pathway
Authors: Wang Qiuyi , Yao Xueming , Xu Hui , Lu Daomin , Huang Ying , Tang Fang , Xiao Lina , Ma Wukai
Published: July 2021

Jinwu Jiangu Capsule is a medicinal formula from the Chinese Miao nationality. Leflunomide is recommended in organizational guidelines for the treatment of rheumatoid arthritis (RA). To investigate the effect of Jinwu Jiangu Capsule on PI3K/Akt/mTOR signal pathway in cells taken from RA patients New Zealand rabbits were administrated with Jinwu Jiangu Capsule suspension to prepare serum containing medicine. Lyophilized powder was prepared from this serum for cell treatment. The expression of LC3-II and PI3K, AKT, mTOR were detected by IF and western blot. Moreover, the levels of Atg1, Atg5, Atg14 were detected by RT-qPCR. The results showed that the expression of LC3-II was increased, and fluorescence spot of LC3-II was obvious in high-dose of Jinwu Jiangu Capsule group. Jinwu Jiangu Capsule decreased the level of PI3k, Akt, and mTOR protein, and increased the levels of Atg1, Atg5 and Atg14. Specially, the high-dose of Jinwu Jiangu Capsule had the most obvious inhibitory and up-regulation effects. However, there was no significant difference in the expression of Akt, mTOR and Atg1 in the medium-dose of Jinwu Jiangu Capsule group compared with the leflunomide group. In conclusion, Jinwu Jiangu Capsule regulates autophagy by inhibiting the PI3K/AKT/mTOR pathway in RA.
Socio-Economic Development of the Republic of Crimea in 2018-2020
Authors: Uznarodov Dmitry I.
Published: July 2021

The article examines features of the socio-economic development of the Republic of Crimea in 2018-2020; in the article the main problems that have a negative impact on the socio-economic processes in the republic are highlighted. Using the method of statistical data analysis, the most and least economically prosperous municipalities of the Republic of Crimea are identified. Problems, that have a negative impact on the socio-economic processes in the republic, include a low GRP per capita, high prices for food products, too fast growth rates of prices for utilities, significant differentiation of municipalities of the republic in terms of average wages of the population and the level of unemployment. In conclusion, in the article the recommendations for reducing the overall level of social tension in the republic are given.
The Number of North Caucasian Abazins in the Middle of the 18th Century
Authors: Karmov Ruslan K.
Published: July 2021

The calculation of the number of Abazins in 1744-1753 is held in the article. Existing and newly discovered archival materials are taken into account. Determining the number of the Abaza population will give wide opportunities for a more complete study of the processes that took place in the past. The article analyzes statistical data regarding the Abaza people who lived and live on the northern slope of the Caucasian ridge. The present number of Abazins is compared with the population of Kabarda in the 18th century. It is concluded that the Abazins in the study period were a fairly large ethnic group, only slightly inferior to the Kabardins. New information on this topic is confirmed by archival documents and map data from 1744.
Popularization of Books and Reading Culture in Soviet City in the 1950s-1960s
Authors: Yarmolich Fedor K.
Published: July 2021

The readership of the Soviet Union was considered to be one of the most massive in the world, which was facilitated by the purposeful policy of the Soviet government in popularizing the printed word: the creation of an extensive library network in the city; propaganda through the mass media of book products; explanation of how to work with book, magazine; holding reader conferences, etc. This example of the popularization of the printed word among the population in the USSR can be relevant at the present time, when a significant part of the Russian population spends less and less of their leisure time reading books, when the skill of a person's work on the scientific text, popular science or artistic content is lost. The involvement of sociological research, periodicals and archival documents allows not only to restore the mechanism of popularization of the book in the Soviet Union, but also to trace how it became possible to instill in a person a culture of reading a wide range of literature from ideological to popular science.
The Consequences of School Dropout in the Kadey Division of Batouri; East Region of Cameroon
Authors: Ndjouma Wedjou Maurice
Published: July 2021

The agenda for sustainable development 2030 has been established and approved by the general assembly of the United Nations in 2015. This agenda includes 17 goals adopted by several countries to promote the development of local communities by tackling and reducing the consequences of school dropout. The continent of Africa through the agenda 2063 endorses different aspirations that have to be met by the year 2063 to minimize the consequences of school dropout, which would lead to a peaceful and protected Africa. The Cameroon Vision 2035 also defined a practical vision of long-term development in the country of Cameroon founded on the eradication of the consequences of school dropout. However, school dropout remains a reality worldwide and generates several consequences which drastically impact the lives of people. It is on this evidence that this research work aimed at exploring the consequences of school dropout in the Kadey Division, East Region of Cameroon.  This study refers to the qualitative research method using the subjectivism ontology and the inductive approach. The epistemology is interpretivism and the axiology is value-bias. The research also employs interviews as the sampling strategy, and 20 respondents gathered in 4 focus groups representing the educational stakeholders of the Kadey Division have volunteered to participate in these interviews. Data were analyzed through the various coding of the grounded theory including open coding, axial coding, and selective coding. The social, education, and economic consequences of school dropout were identified as well. Parents and educators must acknowledge that school failure has this particularity that it penalizes a child for the rest of his life. Any student who stops his studies before having completed his secondary school or vocational training has fewer opportunities to grow within the society. This study recommends that the community stakeholders in the Kadey Division, East region of Cameroon must work collaboratively on minimizing the consequences of school dropout to contribute to the sustainable development of this locality
Escrita acadêmica e (re)construção do dizer: a busca pela autoria do texto na reapropriação da palavra alheia
Authors: Zaidan Bicalho Fonseca Janaina
Published: July 2021

Este trabalho objetiva problematizar a escrita produzida na universidade, tomando como ponto de partida uma experiência didática realizada com acadêmicos do 2º período do curso de História, na disciplina de Leitura e Produção de Textos, durante o segundo semestre de 2019. Para a execução deste estudo, fiei-me nas possibilidades de reconstrução dos dizeres acionados pelos estudantes, com a finalidade de analisar como as tessituras textuais feitas por eles indiciam ou não uma escrita autoral. O referencial teórico girou em torno de uma perspectiva discursiva de língua, principalmente das contribuições de Foucault e Bakhtin.
Editor's Note
Authors: Schussler Aura-Elena
Published: July 2021

The present volume is dedicated to the 2nd Edition of the National Conference “Human Nature, Culture, Technology (NUCT 2021)” with the theme: Life and Death in the Context of the COVID-19 Crisis—A Posthumanist Approach. The volume provides a really exciting opportunity for the reader, with respect to the context of the current COVID-19 pandemic, analyzed in the posthuman paradigm, to take into account the importance of posthumanist critiques, at a time of great changes at the existential level. The contributors to this volume include several scholars from various fields of analysis including philosophy, ethics, medicine, technology, politics, culture, and communication—and their reflections in the critical posthumanism parameters, with regard to how life and death (both at a human and non-human level) was and still is managed during the COVID-19 pandemic.
Experience with dexmedetomidine for sedanalgesia during rhinosurgery
Authors:   Penza Institute for Advanced Training of Doctors, a branch of DPO RMANPO, Penza, 440060, Russia, Grigor’kina E. S. , Vingovatova N. M. ,   Clinical Hospital „RZD-Medicine“, Penza, 440000, Russia, Emelina N. G. ,   Clinical Hospital „RZD-Medicine“, Penza, 440000, Russia, Nedovarov V. G. ,   Clinical Hospital „RZD-Medicine“, Penza, 440000, Russia
Published: July 2021

The aim of this work was to study the possibility of rhinosurgical interventions using the drug dexmedetomidine for controlled sedoanalgesia. Materials and methods: 118 rhinological interventions (polysinusotomy, pansinusotomy, septoplasty) were performed under combined sedation: 56 with dexmedetomidine and 62 with sibazone. Intraoperatively, the amount of narcotic analgesic and local anesthetic, pain level and depth of sedation, hemodynamic and respiratory parameters, bleeding intensity and operating visibility were considered; in the postoperative period - the level of pain, bleeding when removing tampons from the nose, satisfaction of the surgeon and the patient. Results: during sedanalgesia with dexmedetomidine, the optimal level of sedation was achieved, the amount of narcotic and local anesthetic was reduced, hemodynamic parameters were comfortable for the surgeon (lower than in the control group, blood pressure), which, first of all, provided good operational visibility. In the postoperative period, there was a higher satisfaction of the patient and the surgeon with the performed anesthetic aid. Conclusions: sedoanalgesia with the drug dexmedetomidine can be used in uncomplicated cases during rhinosurgical interventions as an alternative to endotracheal anesthesia, providing optimal pain relief and comfortable work of the surgeon.
Case report of two patients with silent sinus syndrome
Authors:   Saint Petersburg Research Institute of Ear, Throat, Nose and Speech,  Saint Petersburg, 190013, Russia, Zakharova G. P. , Ivanov N. I. ,   Saint Petersburg Research Institute of Ear, Throat, Nose and Speech,  Saint Petersburg, 190013, Russia
Published: July 2021

SMS is a rare pathology of the paranasal sinuses, accompanied by such symptoms as pain in the eye area, enophthalmos and hypophthalmos on the side of the localization of the process, facial asymmetry caused by a decrease in the volume of the maxillary sinus due to its atelectasis in the presence of chronic inflammation in it. The disease, as a rule, proceeds under the primary diagnosis of chronic rhinosinusitis. The main pathogenetic link of the disease is generally accepted as the block of the anastomosis and the emergence of the valve mechanism of ventilation of the maxillary sinus. However, the immediate cause of the onset of atelectasis remains a subject of discussion to this day. The only effective surgical treatment is to restore ventilation of the maxillary sinus by expanding the anastomosis and eliminating the cause of its block. With a pronounced asymmetry of the face due to the lowering of the orbit, the plastic of the lower wall of the orbit is performed. The article discusses modern ideas about the silent sinus syndrome, its etiology, pathogenesis, clinical course and treatment tactics for patients, presents two clinical observations of patients with silent sinus syndrome and describes the options for surgical treatment and its results.