bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of photodynamic therapy as an adjunctive to mechanical debridement on the nonsurgical treatment of peri-implant mucositis: A randomized controlled clinical trial
Authors: Pourabbas Reza , Khorramdel Azin , Sadighi Mehrnoosh , Kashefimehr Atabak , Mousavi Seyed Amin
Published: January 2023

Background:

The use of photodynamic therapy (PDT) has been evaluated as an adjunctive technique for bacterial decontamination of implants with peri-implantitis. Given the controversies over the efficacy of the application of PDT to treat peri-implant diseases, the present clinical study aimed to evaluate the posttherapeutic clinical parameters and cytokine levels in peri-implant crevicular fluid in patients with peri-implant mucosal inflammation, receiving mechanical debridement (MD) alone or in association with PDT.

Materials and Methods:

In this double-blinded randomized clinical trial, 52 patients with peri-implant mucosal inflammation were selected and they were randomly assigned to 2 treatment groups: a MD group and an MD + PDT group using an 805 nm laser and indocyanine green (ICG). Although the decrease in bleeding on probing was the primary outcome, pocket depth, PUS, pain on probing, clinical attachment level, gingival recession, tumor necrosis factor-α, interleukin (IL)-1β, IL-6 and matrix metalloproteinase-8 were also evaluated at baseline, 2-week, and 3-month postintervention. Repeated measure analysis of variance was used to analyze inter-group differences and a P ≤ 0.05 was considered for significant differences between tested parameters.

Results:

Statistically significant improvements (P < 0.001) were detected for all variables after comparison of baseline data with those collected at each time interval of the study. Nevertheless, the inter-group comparisons of these variables between the baseline, 2-week, and 3-month intervals did not reveal any significant decrease in sites treated with either MD alone or MD + PDT.

Conclusion:

The application of PDT using 805-nm laser and ICG as an adjunct therapy to MD did not provide any additional improvements in the clinical or biologic parameters of peri-implant mucosal inflammation.
Effect of hydrochloric acid, sodium hypochlorite, and autoclave sterilization on the force characteristics of orthodontic NiTi-closed coils
Authors: Noorollahian Saeed , Khaleghi Amin
Published: January 2023

Background:

This study presented a cleaning method for orthodontic NiTi-closed coils and evaluated its effect on the force characteristics of these coils.

Materials and Methods:

In this in vitro study, 160 orthodontic NiTi-closed coils, 160 orthodontic NiTi-closed coils (9 mm) from two brands G and H and DB, randomly assigned into four groups. Group 1: Three times of immersion in the 10% hydrochloric acid (HCI) solution for 1 min followed by the immersion in 5.25% sodium hypochlorite solution for 5 min. Group 2: Three times autoclave sterilization. Group 3: Three times of immersion in 10% HCI solution for 1 min, followed by the immersion in 5.25% sodium hypochlorite solution for 5 min and autoclave sterilization. Group 4: No immersion and no sterilization. The forces of coils were measured at 25, 23, 21, 19, and 17 mm extension. To measure the force characteristics of coils, an electromechanical universal testing machine was used. For the statistical analysis, Kolmogorov–Smirnov, Kruskal–Wallis, and Mann–Whitney U-tests were used at 0.05 significance level.

Results:

In G and H coils, no significant differences between the mean forces of different groups were found in any extensions. In DB coils, only in 25 mm extension, there were no significant differences between the groups (P = 0.144). In 17-, 19-, and 21-mm extensions, significant differences (P < 0.001) were found like in 23 mm extension (P = 0.05). In both brands, more extension makes significant more forces statistically (P < 0.01). In all extensions, G and H coils have significant less forces (P < 0.001).

Conclusion:

Immersion in HCl, 10% for 1 min followed by the immersion in NaOCl, 5.25% for 5 min followed by autoclave sterilization, even three times repeating of this process, did not result in significant changes in the force characteristics of A-NiTi-closed coils.
Robotic-assisted microsurgery in andrology: a systematic review
Authors: Douroumis Konstantinos , Spartalis Eleftherios , Stravodimos Konstantinos , Levis Panagiotis K , Tsourouflis Gerasimos , Dimitroulis Dimitrios , Nikiteas Nikolaos I
Published: January 2023

Robot-assisted surgery is the gold standard of treatment in many fields of urology. In this systematic review, we aim to report its usage in andrology and to evaluate any advantages. A systematic search of the PubMed and Cochrane Library databases was conducted to identify articles referring to robotic-assisted microsurgery in andrology. The search strategy was in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Cochrane Handbook. The articles were then reviewed by two authors. A qualitative analysis of the articles that met the inclusion criteria was performed. Thirty-one articles that met the inclusion criteria were reviewed. The first results for robot-assisted vasovasostomy (RAVV) are encouraging as excellent patency rates, short operative times, and learning curves were achieved. Interestingly, patency rates were greater in some case series for RAVV than for microsurgical vasovasostomy, with a statistically significant difference. In addition, robot has been shown to be of great use in bypassing fibrotic changes in cases of iatrogenic vasal injuries, difficulties encountered with traditional microsurgery. In addition, the feasibility of robot-assisted microsurgery has been proven for varicocelectomy and microsurgical denervation of the spermatic cord, with acceptable improvement in sperm parameters and pain, respectively. The current evidence suggests that there are potential advantages of the use of robots in andrology. However, for robotic surgery to become incorporated into the daily use of the andrologists, large, multicenter randomized trials are needed. As robotics systems are becoming standard in urology practice, it is reasonable for one to believe that they will also find their place in andrology.
A decade of WHO 2010: total sperm number temporal trend and role of lifestyle factors
Authors: Cargnelutti Francesco , Pallotti Francesco , Carlini Tania , Faja Fabiana , Vestri Anna Rita , Fegatelli Danilo Alunni , Lenzi Andrea , Lombardo Francesco , Paoli Donatella
Published: January 2023

After a huge decline in sperm concentration between 1938 and 1991 was reported, many researchers investigated the possibility of a worsening of human sperm quality. Despite massive efforts, published evidence is still controversial. Similarly, the role of lifestyle factors on semen parameters is debated. We conducted a monocentric Italian study to evaluate the total sperm number trend over the last 10 years (from 2010 to 2019). Additionally, we evaluated the association between lifestyle factors and total sperm number in order to identify possible damaging factors. We performed a retrospective study analyzing subjects aged 18–55 years who had their semen analyzed between 2010 and 2019. A total of 3329 subjects were included: 1655 subjects referred to our department (Department of Experimental Medicine, Sapienza University of Rome, Roma, Italy) for idiopathic infertility and 1674 subjects referred for preconceptional or andrological screening with no confirmed andrological diseases. Semen samples were examined according to World Health Organization (WHO) 2010 criteria by two seminologists with the same training and the same equipment. For statistical evaluations, only total sperm number (×106 per ejaculate) was taken into consideration. We detected no significant changes in mean total sperm number during the last decade, in either the entire population or the two subgroups (infertile group and control group). In a multivariate analysis total sperm number was significantly associated with the history of infertility, body mass index (BMI) and cigarette smoking. Our results suggest that infertile men are “vulnerable” subjects, particularly susceptible to several negative factors, many of which still remain unknown. Our study highlights the need for studies addressing men’s lifestyle in order to find and reduce deleterious agents.
Cholinergic Deficiency in the Cholinergic System as a Pathogenetic Link in the Formation of Various Syndromes in COVID-19
Authors: Lysenkov Sergey Petrovich , Muzhenya Dmitriy Vitalevich , Tuguz Aminat Ramazanovna , Urakova Tamara Ur'evna , Shumilov Dmitriy Sergeevich , Thakushinov Ibragim Askarbievich , Thakushinov Rustem Askarbievich , Tatarkova Elena Anatolevna , Urakova Diana Muratovna
Published: January 2023

According to recent data, several mechanisms of viral invasion of the central nervous system (CNS) have been proposed, one of which is both direct penetration of the virus through afferent nerve fibers and damage to the endothelium of cerebral vessels. It has been proven that the SARS-CoV-2 virus affects pathologically not only the human cardiorespiratory system but is also associated with a wide range of neurological diseases, cerebrovascular accidents, and neuromuscular pathologies. However, the observed post-COVID symptom complex in patients, manifested in the form of headache, “fog in the head,” high temperature, muscle weakness, lowering blood pressure, does it make us think about the pathophysiological mechanisms that contribute to the development of this clinical picture? One possible explanation is a disruption in the signaling of the acetylcholine system (AChS) in the body. Viral invasions, and in particular COVID-19, can negatively affect the work of the AChS, disrupting its coordination activities. Therefore, the main goal of this literature review is to analyze the information and substantiate the possible mechanisms for the occurrence of post-COVID syndrome in people who have had COVID-19 from the standpoint of AChS dysfunctions.
Clinical Significance of Repeat Fine-Needle Aspiration in Managing Patients with Suppurative Lesion
Authors: Elancheran M , Siva K , Sriram V , Archana V , Ragavendran S
Published: January 2023

Background:

Fine-needle aspiration (FNA) has been challenged about its role in the management of patients with clinical suspicion of infective or neoplastic etiology but cytological picture showing features of acute suppuration. This study emphasizes the need to perform repeat FNA cytology (FNAC), especially if the mass lesion is indicating suppuration and has not responded to the initial course of antibiotics.

Materials and Methods:

All patients with a previously diagnosed suppurative lesion on cytology smears who have undergone repeat FNA were included in the study. Insufficient material on FNA and the nonavailability of slides were excluded from this study.

Results:

Repeat FNA assisted in the detection of malignant lesions (3), tubercular lesions (20), fungal lesions (9), and benign lesions (9) out of the 123 cases of previously diagnosed acute suppurative lesions. Comparison of FNAC findings with histopathological specimens was available for 52 cases, following which repeat FNA had a sensitivity of 66.67% (95% confidence interval 34.89%-90.08%) in detecting neoplastic, specificity was 100%, positive predictive value was 100%, negative predictive value was 90.91%, and the total diagnostic accuracy was 92.31%.

Conclusion:

Patients with acute suppurative lesions should be followed by repeat FNA, especially if the lesion is not responded to initial antibiotic therapy. Repeat FNA will enhance the diagnostic accuracy of malignant lesions and many other lesions, such as fungal or tubercular infections. It will reduce the need for surgical interventions and molecular detection of infectious diseases.
Low Back Pain Among Nurses as Related to Work Environment
Authors: Osunde Ngozi Rosemary , Nwozichi Chinomso Ugochukwu , Olorunfemi Olaolorunpo , Sodimu Jaminat Omotade , Olorunfemi Omotayo Mercy
Published: January 2023

Background:

Low back pain (LBP) is a major problem in the nursing profession and it is been reported that more nurses experience LBP during the nursing practice. Studies show that only 15.9% of nurses had LBP before coming into nursing while 84.5% complained they had LBP after working in the nursing environment.

Aim:

The aim of this study was to determine factors responsible for low back ache, as related to the work environment in the University of Benin Teaching Hospital, Benin City, Nigeria.

Materials and Methods:

A cross-sectional descriptive study was conducted from January 2019 to February 2020, with probability sampling to select a sample size (n = 260). Data collected were analyzed using tables; percentages, bivariate analysis, and and multivariate logistic regression were used for data analysis at 0.05 level of significance, through a statistical package for the social science software.

Results:

Among 260 nurses with backache, 159 (61.15%) were male and most of the participants' ages were between 25 and 34 years, with a mean age of 26.5 (0.37). The multivariate logistic regression analysis showed that heavy manual lifting (odd ratio [OR] 0.21, 95% confident interval [CI] 0.54–0.73), body posture (OR 0.31, 95% CI 0.20–1.08), the length of working shift (OR 0.60, 95% CI 0.74–0.86), awkward postures (OR 0.68, 95% CI 0.65–1.10), and prolonged standing during nursing care (OR 0.73, 95% CI 0.52–1.00) were the major factors for LBP among nurses, with <0.001, 0.001, 0.002, 0.002, and 0.003, respectively.

Conclusions:

The finding implies that all effort should be directed toward policies which have positive effects on proper management of the work environment and other conditions, such as health and safety training. Prevention of work overloads through appropriate work shifting, and the mechanism of body posture should be improved. Furthermore, periodical flexing of feet, knees, and hip is necessary in a condition where there is a need to stand for a long period of time.
Intrapartum Electronic Fetal Monitoring and Perinatal Outcomes
Authors: Kumari Minakshi , Abraham Anuja , Abraham Kavitha , Navaneethan Preethi , Karuppusami Reka , Sridhar Santhanam , Regi Annie
Published: January 2023

Aim:

The aim of this study was to assess the components of cardiotocography (CTG) during labor to identify the variables associated with the risk of adverse perinatal outcomes and to ascertain the mode of delivery in these women.

Materials and Methods:

This prospective observational study included 191 women at term with singleton pregnancy in labor. The CTG findings including baseline heart rate, accelerations, beat-to-beat variability, and type and severity of decelerations were noted as per the International Federation of Gynecology and Obstetrics classification and grouped into Category II or III patterns as per the National Institute of Child Health and Human Development classification. Low APGAR score, cord PH <7, neonatal intensive care unit admission, respiratory distress, and hypoxic-ischemic encephalopathy were considered adverse neonatal outcomes.

Results:

Persistent fetal tachycardia, poor beat-to-beat variability, and severe variable deceleration showed a significant association with adverse neonatal outcome and delivery by cesarean section (P < 0.05). Adverse neonatal outcomes were noted in 4.2% of babies and 40.9% of babies born to mothers whose CTG was categorized as II and III patterns, respectively (P < 0.001). Birth by cesarean section was significantly different between those with Category II and Category III patterns, 33.7% and 65.4%, respectively (P < 0.01).

Conclusion:

Reduction in the beat-to-beat variability and presence of severe variable decelerations are independent risks for adverse neonatal outcomes, irrespective of the category of CTG pattern. Category III fetal heart rate pattern shows a significant association with adverse outcomes and risk of cesarean delivery. Grading the Category II patterns may help in identifying variables that are truly associated with acidemia and further research into this is recommended.
Comparative Evaluation of Push-Out Bond Strength of AH-Plus, MTA-Fillapex and Epiphany SE Root Canal Sealers
Authors: Chandarani Sagolsem , Gundappa Mohan , Chowdhary Zoya , Singh Deepika , Swarup Neeti , Mehrotra Shalabh
Published: January 2023

Background:

A successful root canal (RC) treatment depends upon creation of a fluid impervious seal that is commonly built by using a RC sealer along with gutta-percha. The bond strength of the RC sealer is a hallmark as it will minimize the risk of treatment failure by reducing the possibility of filling detachment from dentin.

Aim:

To evaluate and compare the push-out bond strength of AH-Plus and MTA-Fillapex with Gutta-Percha and Epiphany Self Etch/Resilon system using the Universal Testing Machine.

Materials and Method:

About 60 mandibular premolars with single canals were prepared apically with Hyflex CM files upto size #30. Out of total, 20 teeth were obturated with AH-Plus/GP (group 1), 20 with MTA-Fillapex/GP (group 2), and other 20 with Epiphany Self Etch/Resilon system (group 3). Teeth were sectioned into three slices of 2 mm each and were subjected to Universal Testing Machine.

Statistical Analysis:

The data obtained were tabulated and statistically evaluated using SPSS version 21.0 statistical analysis software (IBM, Chicago, Illinois, USA).

Results:

The mean push-out bond strength was highest for AH–Plus (14.32 MPa) followed by MTA-Fillapex (12.18 MPa) and then Epiphany SE (8.44 MPa). The results were statistically significant.

Conclusion:

Significantly, higher push out bond strength was displayed by AH-Plus sealer than MTA-Fillapex and least being Epiphany SE sealer. The push out bond strength was significantly highest at apical third and lowest at coronal third.
Knowledge, Attitudes, and Beliefs Among Dental Students and Faculty Members Regarding COVID-19 Vaccines in Dental Colleges of Haryana, India - A Cross-Sectional Study
Authors: Chauhan Neha , Manjunath BC , Kumar Jadhav Sachin , Yadav Vipul , Sabbarwal Bhavna , Kumar Adarsh
Published: January 2023

Aim:

To assess knowledge, attitudes, and beliefs among dental students and faculty members regarding COVID-19 vaccines in dental colleges in Haryana, India.

Objectives:

To assess knowledge level, attitudes, and beliefs differences among BDS, MDS students and faculty members and find association between knowledge and COVID-19 vaccine inoculation among study participants.

Materials and Methods:

A cross-sectional study was carried out among students and faculty members of dental colleges in Haryana, India. Data collection was done via an online questionnaire based on questions to assess the knowledge, attitude and beliefs regarding COVID-19 vaccines.

Results:

The present study comprised of 270 study participants, where majority, i.e., 81.5% have reported COVID-19 vaccine inoculation. The mean knowledge score of the participants was reported to be 5.54 ± 2.19. A significant difference was found in the mean knowledge score of faculty members (7.81 ± 1.69), MDS (6.72 ± 1.49), and BDS (4.39 ± 1.68) students. COVID-19 vaccine inoculation was found to be significantly associated with average knowledge score of participants (OR = 6.1, P < 0.01).

Conclusion:

Dental professionals have an adequate degree of knowledge and attitude level regarding COVID-19 vaccines and are generally optimistic about resolving the pandemic situation with the immunization.
Assessment of Biological Risk among Dentists during the COVID-19 Pandemic—A Cross-Sectional Study
Authors: Devaraj Divya K. , Hussain Alikunju Syed Khaja , Murugesan Mohandoss
Published: January 2023

Background:

The health and life of a healthcare worker are repeatedly under threat due to the rising number of epidemics and pandemics. The COVID-19 pandemic is said to be fatal in people with a risky biological, demographic profile and working environment. This study is the first of its kind carried out on the dentist population from India, who were most affected during the COVID-19 pandemic.

Aims and Objective:

The present study aims to assess the biological risk of dentists based on the objective risk stratification (ORS) tool developed by Strain et al.

Materials and Methods:

This was a cross-sectional study of dentists in government dental colleges of Kerala using the online form of the ORS tool consisting of questions which included certain demographic characteristics and comorbid conditions of the individual. An additional question was added to the tool, to categorise the work of the dentist depending on the exposure to aerosol (non-aerosol, minimal aerosol and aerosol).

Results:

Out of the 74 dentists, 48.6% reported high aerosol and 31% with minimal aerosol. The median score of the study participants was 2 (ranging from 1 to 12). Using the ORS tool, 16.2% had medium risk and only 2.7% had high risk. When the ORS tool was stratified with the aerosol generation, 5.4% had minimal and 6.7% had significant with medium-risk scores. Also, 2.7% with a high-risk score had minimal aerosol generation.

Conclusion:

Identifying the high-risk category to allocate duties accordingly and decrease the morbidity and mortality among dentists has to be kept a top priority in the event of a pandemic.
Comparative Effectiveness of Herbal and Conventional Toothpaste on Prevention of Dental Caries
Authors: Kengadaran Shivashankar , Anusha Divvi , Baskar Kavya , Muthukrishnan Kavitha , Pooraninagalakshmi J , Prabakar Jayashri
Published: January 2023

Dental caries is a global oral health problem caused due to localized demineralization of the enamel. Chemical plaque control is used as an adjuvant to mechanical plaque control in removing biofilm, thereby preventing dental caries. In recent times, there has been a renewed interest in nature-based products. This systematic review aimed to analyse the existing literature to compare the effectiveness of herbal and conventional dentifrices on prevention of dental caries. A search was done in the databases of PubMed and Google Scholar in July 2020 for the related topic. A hand search was done from the references of primary studies and other clinical trial registry sites. Randomized control trials, comparative clinical trials, and in vitro studies in which the effectiveness of herbal and conventional dentifrices on prevention of dental caries were included after review by the reviewers. The systematic search revealed a total of thirty-two publications from which ten publications were included. Five studies were clinical studies and five were in vitro studies. All the studies used microbiological analysis for the determination of cariogenic microorganisms in plaque and saliva, whereas one study used pH of plaque and saliva. Among the included studies, all studies had a high risk of bias with level 2 evidence. With the evidence available, it can be concluded that herbal dentifrices and fluoride dentifrices have similar antimicrobial activity against cariogenic microorganisms.
The Effect of Metallic Dental Restorations and Implants in Causing Patient Discomfort and Artefacts During Magnetic Resonance Imaging of the Head and Neck
Authors: Ashok Aiswarya , Ayyadanveettil Pramodkumar , Devarajan Ellezhuthil , Thavakkara Vinni , Latha Neethu , Saraswathy Arya
Published: January 2023

Context:

Patients with metallic dental objects in their oral cavity are often associated with discomfort or artefacts during magnetic resonance imaging (MRI) of the head and neck.

Aim:

This study was conducted to evaluate the effects of metallic dental objects in causing patient discomfort and artefacts during MRI of the head and neck region.

Design:

This is an observational study including 538 participants from various specialized MRI centres in Kozhikode.

Methods and Material:

MRI records of 538 participants who underwent head and neck MRI as a part of their medical treatment were collected. With the help of questionnaire and clinical examination, the type of metallic dental object in the patient's oral cavity was identified. After examining the MRI images, four categories of artefacts were established. In MRI brain, artefacts in three different sequences were also studied.

Statistical Analysis Used:

The significance of the difference between proportions was analysed by the Chi-square test.

Results:

Artefacts were found in 65 cases with metallic dental objects but none of the participants had experienced any kind of discomfort. The artefact formation significantly depended on the type of metallic dental restoration in the patient's oral cavity. Orthodontic braces and titanium bone plate created severe artefacts in head and neck MRI making interpretation almost impossible. In the MRI brain, diffusion-weighted imaging is most sensitive to artefact followed by fluid-attenuated inversion recovery.

Conclusions:

Artefacts were found in 65 cases with metallic dental restorations but none of the participants had experienced any kind of discomfort.
Effectiveness of Molecular-Targeted Chemotherapy in Ameloblastomas
Authors: Yoithapprabhunath Thuckanaickenpalayam R. , Srichinthu Kenniyan K. , Gupta Deepak , Singh Diksha , Pasupuleti Swetha , Nirmal Ramdas M.
Published: January 2023

Ameloblastoma is a benign, locally aggressive neoplasm that needs extensive surgical resection. The goal of this article is to obtain an in-depth review of benign ameloblastomas to determine the available level of evidence and the possible benefit of targeted therapeutics for the treatment of ameloblastoma and BRAF V600E mutation in ameloblastoma. An electronic literature search was conducted according to PRISMA guidelines in PubMed/MEDLINE, EBSCO, and Web of Science for eligible studies published between 1975 and 2021. The systematic review is registered with INPLASY (INPLASY202260018). The review included 2 case series and 17 case reports. The histopathological type, anatomic location, expression of BRAF mutation, additional mutations, and molecular-targeted therapies of the 19 reviewed articles were summarized and tabulated. Interestingly, the majority of the primary site of ameloblastoma was located in the mandible (80.9%) compared to the maxilla (17%). The tumour size was reported in nine of the included studies. Most of the included studies in the review exhibited ameloblastoma with BRAF V600E mutations and responded to molecular-targeted therapies. Molecular therapies employing BRAF and/or MEK inhibitors in ameloblastoma with BRAF V600E mutations proved to be an appropriate treatment based on the limited available evidence. It is essential further to deepen our understanding at the clinical and molecular level to enhance the precision of management of ameloblastoma.
Multi-Disciplinary Orthodontic Camouflage Treatment of a Severe Skeletal Class III Malocclusion with 1 Year Follow-Up – A Case Report
Authors: Adeni Moina K. , Parameswaran Ratna , Vijayalakshmi Devaki , Sainulabdeen Junaid
Published: January 2023

Rationale:

Orthodontic camouflage serves its purpose in treating mild to moderate skeletal dysplasia and in conditions where the patient is reluctant to opt for orthognathic surgery or when it is contraindicated.

Patient Concerns:

A 22-year-old male was concerned about his irregular teeth.

Diagnosis:

Angle's dentoalveolar class III malocclusion on class III skeletal on an average mandibular plane angle with anterior crossbite, deep bite, crowding in maxillary and mandibular anteriors, proclined maxillary anteriors and retroclined mandibular anteriors with reverse overjet and congenitally missing 12, 22, palatally impacted 13 and retained deciduous 63 and palatally placed 23.

Treatment:

Orthodontic camouflage with a multi-disciplinary approach.

Outcome:

Optimal functional and dentofacial aesthetics were achieved by 22 months.

Take-Away Lesson:

The limitations of camouflage must be kept in mind and explained to the patient. The biomechanics need to be customized and integrating different specialties helps maximize the treatment benefits.
Burden of Oral Precancer and Cancer among an Indigenous Tribal Population of South India – An Evaluative Study
Authors: Muthanandam Sivaramakrishnan , Babu Bontha V. , Muthu Jananni , Rajaram Suganya , Sundharam B Sivapatha , Kishore M
Published: January 2023

Context:

Oral cancer is of major concern in the Indian subcontinent and is found to be high among low socioeconomic groups. One such high-risk group is considered to be the tribal people, who are economically and socially marginalised.

Aims:

The aim of the present study is to assess the prevalence of oral cancer and precancer lesions among the Narikurava population in Puducherry state, India.

Methods and Material:

A total of 329 Narikurava tribal people were included in this study. Data was collected by clinical examination of the oral cavity by door-to-door screening. The oral cavity was examined for white/red lesions, ulcerative changes, leathery changes and tissue growths.

Statistical Analysis Used:

Prevalence was calculated in terms of percentages. Descriptive statistics included the calculation of percentages, mean, and standard deviation.

Results:

The prevalence of precancer in the population is 48.3%. The majority of the lesions were observed in the buccal mucosa: 41.6% had white lesions, 9.1% had red lesions, 0.3% had ulcerations or growth, and 28.3% had leathery changes followed by the labial mucosa: 0.6% had white lesions, 0.6% had red lesions, 0.3% had ulcerations or growth and 16.4% had leathery changes.

Conclusions:

The present study observed a high prevalence of precancerous lesions among the Narikurava tribe. The main reason for the high prevalence is attributed to tobacco and tobacco-related habits. Hence, cancer control activities should be prioritised. Designing a model to detect precancer and cancer early and to constantly monitor the detected cases in such populations is of utmost importance.
Evaluation of Serum and Gingival Crevicular Fluid Levels of Vitamin D Binding Protein in Subjects with Clinically Healthy Periodontium and Chronic Periodontitis
Authors: Chakravarthy Yashaswini , Mishra Ashank , Krishnan Preeti , Pathakota Krishnajaneya Reddy , Vijaya V , Kamatham Shanthi Naidu
Published: January 2023

Background:

Advances in oral and periodontal disease diagnostic research are moving towards methods wherein periodontal risk can be identified and quantified by objective measures such as bio-markers. Given the roles of vitamin D binding protein (DBP) in modulating the immune response and in the transport of vitamin D, it is hypothesised that quantitative changes of vitamin DBP are associated with periodontal disease.

Aim:

The aim of the current study is to measure DBP levels in serum and gingival crevicular fluid (GCF) of patients with generalised chronic periodontitis, in comparison to healthy controls.

Materials and Methods:

The present cross-sectional clinico-bio-chemical study includes 30 systemically healthy subjects with 15 periodontally healthy and 15 chronic periodontitis subjects who were recruited from the out-patient Department of Periodontics. GCF and blood samples were collected from all the patients. DBP estimation was performed in both the samples using a commercially available ELISA kit.

Results:

Serum and GCF DBP levels in chronic periodontitis subjects were significantly higher when compared to the periodontally healthy group. There were no significant correlations found among serum and GCF DBP levels with gender and increasing age in both the groups. An increase in disease severity measured by the increase in probing pocket depth and clinical attachment loss did not show correlation with the GCF and serum DBP levels in the chronic periodontitis group.

Conclusion:

Based on the findings of the present study, increased serum and GCF DBP levels in chronic periodontitis seem to be a probable marker for identifying ongoing periodontal destruction.
Secular Trends in Prevalence of Overweight and Obesity Over a Decade in Urban and Rural South Indian Children Integrated with Geographic Information System
Authors: Chanchala HP , Madhu B , Nagaraja Manjunatha S. , Shanbhog Raghavendra
Published: January 2023

Context:

The globalization in the process most of the rural sectors are also upgrading technically with digitalization with more availability of smart phones and gaming along with the refined food influences on the present-day children is causing a trend of overweight among the children.

Aims:

To arrive at the prevalence of overweight and obesity considering the Indian Academy of Pediatrics (IAP) cut-offs for growth standards among children aged 12 years from the rural and urban areas of Mysuru District.

Methods and Material:

The present program was the third large scale community intervention project carried out including the 7 talukas of Mysuru District which focused on the measurement of the Body mass index (BMI). In this phase between the year 2019 and 2020 anthropometric measurements were undertaken in 1602 urban and rural children aged 12 years from government-funded and privately-funded schools of Mysuru District.

Statistical Analysis Used:

The results were analysed statistically using SPSS for Windows (version 23.0) and the t-test, Chi-square test and proportion tests, P value were reported. Results: As per the IAP reference ranges the prevalence of obesity was 5.5% and overweight was 7.1% among children of Mysuru District.

Conclusions:

We report that this increase was significantly higher in girls than boys. There was an increasing trend in rural sectors; however, the obese children were more predominantly distributed among the urban sectors. This calls for a precise preventive measure to fulfil the goal of the World Health Organization (WHO) to control prevalence of childhood obesity by the year 2022.
Analysis of Intraoperative Squash Cytology of Central Nervous System Lesions and Its Correlation with Immunohistopathology and Radiology
Authors: Philip Shilpa Accamma , Bai Earla Lakshmi , Padmaja G. J. Vani , Kumari Swarajya
Published: January 2023

Context:

Central nervous system lesions are diverse and remain one of the most challenging domains for neuropathologists. Intraoperative cytological diagnosis is now a universally accepted technique in diagnosis of central nervous system (CNS) lesions.

Aims:

1) To analyze and compare cytomorphological features of CNS lesions in intraoperative squash smears with histopathology, immunohistochemistry, and preoperative radiological diagnosis and 2) to determine the diagnostic accuracy, sensitivity, and specificity of intraoperative squash cytology.

Settings and Design:

Prospective study conducted at a tertiary healthcare centre over a period of two years.

Methods and Material:

All biopsy materials which underwent squash cytology and histopathological examination were collected, evaluated, classified, and graded according to WHO classification of CNS Tumors, 2016. The squash cytosmear diagnosis was compared with histopathological features and radiological diagnosis. Discordances were evaluated.

Statistical Analysis Used:

The cases were categorized into true positives, false positives, true negatives, and false negatives. Diagnostic accuracy, sensitivity, and specificity were calculated from 2*2 table.

Results:

A total of 190 cases were included in the study. A total of 182 cases (95.70%) were neoplastic of which 87.36% were primary CNS neoplasms. Diagnostic accuracy in non-neoplastic lesions was 88.8%. Most common neoplastic lesions were glial tumors (35.7%), meningioma (17.3%), tumors of cranial and spinal nerves (12%), and metastatic lesions (12%). Diagnostic accuracy of squash cytology was higher in glial tumors (93.8%), meningioma (96.7%), and metastatic lesions (95.45%). Diagnostic accuracy of radiological modalities was 85.78%.

Conclusions:

A good familiarity with cytomorphological features of CNS lesions, clinical details, radiological findings, and intraoperative impression of neurosurgeon enables the pathologist to improve diagnostic accuracy and reduce errors.
Deep Model Training and Deployment in Heterogeneous IoT Networks
Authors: Lu Bowen , Lai Shiwei , Tang Yajuan , Cui Tao , Fan Chengyuan , Ou Jianghong , Fan Dahua
Published: January 2023

As a typical form of machines learning, deep learning has attracted much attention from researchers. It can independently construct (train) basic rules according to the sample data in the learning process. Especially in the field of machine vision, neural networks are usually trained by supervised learning, that is, by example data and predefined results of example data. In this paper, we firstly overview the current research progress on the deep model training and deployment on the heterogeneous Internet of Things (IoT) networks, by taking into account both the latency and energy consumption from various devices in the system. We then summarize the existing challenges on the model training and model deployment on the heterogeneous IoT devices. We further give some feasible solutions to solve the challenges on the model training and model deployment on the heterogeneous IoT devices. The study in this paper can serve as an important reference for the development of deep model training and model deployment for heterogeneous IoT networks.
Design a framework for IoT- Identification, Authentication and Anomaly detection using Deep Learning: A Review
Authors: Shoukat Aimen , Hassan Muhammad Abul , Rizwan Muhammad , Imad Muhammad , Farhatullah  , Ali Syed Haider , Ullah Sana
Published: January 2023

The Internet of Things (IoT) connects billions of smart gadgets so that they may communicate with one another without the need for human intervention. With an expected 50 billion devices by the end of 2020, it is one of the fastest-growing industries in computer history. On the one hand, IoT technologies are critical in increasing a variety of real-world smart applications that can help people live better lives. The cross-cutting nature of IoT systems, on the other hand, has presented new security concerns due to the diverse components involved in their deployment. For IoT devices and their inherent weaknesses, security techniques such as encryption, authentication, permissions, network monitoring, \& application security are ineffective. To properly protect the IoT ecosystem, existing security solutions need to be strengthened. Machine learning and deep learning (ML/DL) have come a long way in recent years, and machine intelligence has gone from being a laboratory curiosity to being used in a variety of significant applications. The ability to intelligently monitor IoT devices is an important defense against new or negligible assaults. ML/DL are effective data exploration techniques for learning about 'normal' and 'bad' behavior in IoT devices and systems. Following a comprehensive literature analysis on Machine Learning methods as well as the importance of IoT security within the framework of different sorts of potential attacks, multiple DL algorithms have been evaluated in terms of detecting attacks as well as anomaly detection in this work. We propose a taxonomy of authorization and authentication systems in the Internet of Things based on the review, with a focus on DL-based schemes. The authentication security threats and problems for IoT are thoroughly examined using the taxonomy supplied. This article provides an overview of projects that involve the use of deep learning to efficiently and automatically provide IoT applications.
Data Transmission of Digital Grid Assisted by Intelligent Relaying
Authors: He Shuangbai , Yang Chun , Li Yuda , Xie Binyu , Zhao Jiaqi
Published: January 2023

In this paper, we study the relaying and cache aided digital grid data transmission, where the relaying may be equipped by caching or not, depending on specific applications. For both cases, we evaluate the impact of relaying and caching on the system performance of digital grid data transmission through theoretical derivation. To this end, an analytical expression on the outage probability is firstly derived for the data transmission. We then provide an asymptotic expression on the system outage probability. Finally, some simulation results are provided to verify the correctness of the derived analysis on the system performance, and show the impact of relaying and caching on the data transmission of digital grid system. In particular, the usage of caching at the relaying can help strengthen the data transmission performance of the considered system effectively. The results in this paper could provide some reference to the development of wireless transmission and scalable information systems.
A standardized pathology report for gastric cancer: 2nd edition
Authors: Park Young Soo , Kook Myeong-Cherl , Kim Baek-hui , Lee Hye Seung , Kang Dong-Wook , Gu Mi-Jin , Shin Ok Ran , Choi Younghee , Lee Wonae , Kim Hyunki , Song In Hye , Kim Kyoung-Mee , Kim Hee Sung , Kang Guhyun , Park Do Youn , Jin So-Young , Kim Joon Mee , Choi Yoon Jung , Chang Hee Kyung , Ahn Soomin , Chang Mee Soo , Han Song-Hee , Kwak Yoonjin , Seo An Na , Lee Sung Hak , Cho Mee-Yon ,   The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists
Published: January 2023

The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago. Since then, significant advances have been made in the pathologic diagnosis, molecular genetics, and management of gastric cancer (GC). To reflect those changes, a committee for publishing a second edition of the report was formed within the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists. This second edition consists of two parts: standard data elements and conditional data elements. The standard data elements contain the basic pathologic findings and items necessary to predict the prognosis of GC patients, and they are adequate for routine surgical pathology service. Other diagnostic and prognostic factors relevant to adjuvant therapy, including molecular biomarkers, are classified as conditional data elements to allow each pathologist to selectively choose items appropriate to the environment in their institution. We trust that the standardized pathology report will be helpful for GC diagnosis and facilitate large-scale multidisciplinary collaborative studies.
Characterizing slopes for the -pretzel knot
Authors: McCoy Duncan
Published: January 2023

In this note, we exhibit concrete examples of characterizing slopes for the knot
$12n242$
, also known as the
$(-2,3,7)$
-pretzel knot. Although it was shown by Lackenby that every knot admits infinitely many characterizing slopes, the nonconstructive nature of the proof means that there are very few hyperbolic knots for which explicit examples of characterizing slopes are known.
Formularze dyspozycji czynności prawnych na dokumentach książąt wielkopolskich do 1296 r. – cz. 1: zamiana, kupno-sprzedaż i zastaw
Authors: Pytel Marcin
Published: January 2023

Artykuł jest poświęcony formularzom dyspozycji dokumentów książęcych w Wielkopolsce. W pierwszej jego części zajmuję się formularzami zamiany, kupna-sprzedaży i zastawu. Analizuję te formularze z punktu widzenia dyplomatyki, tak jak dotąd analizowano pozostałe części formularza średniowiecznego dokumentu.

Legal Transaction Disposition Forms on the Documents of Wielkopolska Dukes until 1296 – Part 1: Exchange, Purchase/Sale, and Security

The article is devoted to the disposition forms of ducal documents in Wielkopolska (Great Poland). Its first part discusses the forms for exchange, purchase/sale, and security. The forms are analyzed from the perspective of diplomatics, as have the remaining parts of the form of the medieval documents been so far analyzed.
Насельники Уманського Василіянського Монастиря (1816–1834 роки): Біографічні нотатки
Authors: Stetsyk Yuriy , Kryvosheya Igor
Published: January 2023

W artykule przedstawiono okoliczności powstania i likwidacji klasztoru. Zaprezentowano rezultaty badań autora dotyczących poprzednich okresów historii klasztoru. Prześledzono działania podjęte przez rosyjskie władze okupacyjne w celu ograniczenia działalności i zamknięcia klasztorów bazylianów w prawobrzeżnej Ukrainie. Ukazano działalność szkoły powiatowej przy klasztorze w Humaniu. W załączeniu życiorysy mieszkańców klasztoru. Monitorowano dynamikę liczby mnichów i uczniów szkoły klasztornej. Analizowane są główne cechy prozopograficzne monastycyzmu bazyliańskiego w Humaniu: etapy formacji duchowej i intelektualnej, obowiązki, struktura wieku i czasu.

The circumstances of the foundation and liquidation of the monastery have been revealed. The results of the author's research on previous periods of the history of the monastery are presented. The measures taken by the Russian occupation authorities to limit the activities and close the Basilian monasteries in Right Bank Ukraine were traced. The activity of the Uman district school at the monastery was considered. Biographies of the inhabitants of the monastery are attached. The dynamics of the number of monks and students of the monastery school were monitored. The main prosopographic characteristics of the Uman Basilian monasticism are analyzed: stages of spiritual and intellectual formation, duties, age and time indicators.
Demographic and Economic Characteristics of Population as Determinants of the Revenue From The Real Property Tax in the Slovak Republic
Authors: Maličká Lenka , Lukáčová Jana , Hadačová Daniela
Published: January 2023

This paper examines how the demographic and economic structure of the municipalities´ population relates to the share of real property tax on local tax revenue in the Slovak republic. Shares of the productive population, unemployed population pupils, the population aged less than 14 years, and the population aged over 65 years in the total municipal population are involved in the regression analysis based on the panel data. The research covers 2,926 municipalities in the period 2005-2020. Estimation results show a positive relationship between the dependent variable and variables referring to the productive population, unemployed population, and population aged less than 14 years. A negative relationship is observed in the case of variables referring to pupils and the population aged over 65 years.
Effect of Specific Yogic Asana on Mental Toughness and Stress Level of College Cricketers
Authors: Dr. Kulvinder Singh Bagga
Published: January 2023

Today we see that yoga is being applied in not less than 20 fields quite successfully including other sports like Kabaddi then why not other sports. Remarkably it is also true that many top sports stars are already practicing yoga postures and taking the best advantage. Cricket is long duration playing game which needs mentally strong and tough players to win matches and championships. Due to paramount importance of mental toughness in sports and particular in cricket that present paper focused to compare. Yoga has both preventive and therapeutic benefits. It has been shown to offer both physical and mental benefits to the body and the mind. , the present study was based on a pre-test, post-test design, a total of 100 male subjects were randomly selected from various colleges of Agra university. The subjects were College level batsman, with minimum 5 years of playing experience. The age of the subjects ranged between 20 to 22 years, the mean age was found to be 20.8 years. A pre test was taken of all the selected sports persons on the selected variables of Attention level and stress level, thereafter a yogic Asana program was implemented for 8 weeks and a post test is taken. For the collection of the data mental toughness was checked by Dr. Alan Goldberg (2004) Mental Toughness Questionnaire and stress questionnaire developed by Dave Hompes (2001) were selected. . The collected data was analyzed by computing descriptive statistics followed paired sample t test. A significant difference has been found in the pre and post test values of mental toughness and stress level of the Cricket players due to the yogic practice.