bluuebunny/crossref_metadata_2025 huggingface dataset:
The severity of COVID-19 is accompanied by a change in the expression of the surface marker CD38 in T lymphocytes and NK cells
Authors: Vavilova Julia D. , Boyko Anna A. , Streltsova Maria A. , Kust Sofya A. , Yusubalieva Gaukhar M. , Novikova Oksana N. , Sotnikova Anna G. , Bychinin Mikhail  V. , Ischakov Rustam N. , Sapozhnikov Alexander M. , Kovalenko Elena I.
Published: November 2022

BACKGROUND: COVID-19 mediates activation of immunocompetent cells. Little is known about the phenotypic marker CD38 on the surface of T and NK cells and its association with the severity of COVID-19.
AIM: To analyze the distribution of the surface marker CD38 in subsets of T and NK cells at the different stages of their differentiation in the groups of patients with COVID-19 and convalescents, and to reveal the relationship between the level of CD38 expression in subpopulations of T and NK cells with the severity of COVID-19.
MATERIALS AND METHODS: Peripheral blood mononuclear cells (PBMC) from patients and donors were isolated using ficoll density gradient followed by cytofluorimetric analysis of the surface markers: CD3, CD56, CD38.
RESULTS: In PBMC samples the level of CD38 expression on NK cells (CD3CD56+), including CD56bright and CD56dim subsets, as well as on T lymphocytes, differentiating conventional CD56(CD3+CD56) and NKT-like (CD3+CD56+) cells, were analyzed. Among CD56 T cells and NKT-like cells the highest levels of CD38 expression were registered in the groups of patients of moderate severity and convalescents, and, in contrast, the decreased CD38 levels were detected in the group of patients from the intensive care unit.
CONCLUSIONS: The findings suggest that the level of CD38+ T cell in COVID-19 may be of use as diagnostic value.
Method of obtaining purified SARS-CoV-2 antigen for structural and immunological studies in whole-virion vaccines against coronavirus infection
Authors: Zyrina Anna N. , Tselykh Irina O. , Bogdan Anastasia S. , Kovpak Anastasia , Ivin Yury Yu. , Vasilenko Vladislav E. , Piniaeva Anastasia N. , Shishova Аnna A.
Published: November 2022

BACKGROUND: Despite the large-scale development of vaccines against coronavirus infection, there is still no complete information about the antigenic structure of the SARS-CoV-2 virus particles. This article describes a method of obtaining a pure concentrated whole-virion sample that can be used in various studies.
AIM: The goal is to develop an optimal method of purification of the inactivated SARS-CoV-2 virus in order to obtain a standard with parameters of purity and antigen content sufficient for structural and immunological studies.
MATERIALS AND METHODS: To obtain a pure concentrated virus SARS-CoV-2 we used the sucrose density gradient ultracentrifugation. Fractions with the highest content of viral particles were evaluated based on the concentration of nucleocapsid N and glycoprotein S. The purity of the pooled fractions (the purified sample) was evaluated by the presence of impurity proteins, toxins and bovine serum albumin.
RESULTS: The optimal conditions for obtaining the inactivated purified SARS-CoV-2 whole virus were determined. A standard sample of the inactivated SARS-CoV-2 virus was isolated and characterized.
CONCLUSIONS: The obtained standard sample can be used in enzyme immunoassay to measure the amount of antigen in whole-virion vaccines against coronavirus infection, as well as in various structural studies of SARS-CoV-2 virus particle.
Alphacoronaviruses detected in fecal samples of bats captured in Moscow and Rostov-on-Don in 2021
Authors: Korneenko Elena V. , Samoilov Andrei E. , Artyushin Ilya V. , Yusefovich Alexander P. , Dolotova Sofya M. , Klyuchnikova Ekaterina O. , Sbarzaglia Valeriya A. , Gladkikh Anna S. , Dedkov Vladimir G. , Speranskaya Anna S.
Published: November 2022

BACKGROUND: Bats are a reservoir of a large number of viruses, including coronaviruses. Monitoring viruses in bats is an important task.
AIM: To detect viruses belonging to Coronaviridae family in bats which habitat in European part of Russia.
MATERIALS AND METHODS: We used PCR amplification of viral genome fragments, followed by high-throughput sequencing.
RESULTS: RdRp gene fragments of at least two different alphacoronaviruses (Bat coronavirus, Coronaviridae) were revealed in four bats of three species.
CONCLUSIONS: Our results demonstrate the presence of viruses of the Alphacoronavirus genus in 4 of 17 bats. Coronavirus-positive animals were captured in 2021 in Moscow, Moscow Region and Rostov-on-Don, these four animals have been found to be carriers of different isolates of the same alphacoronavirus, which allows us to suggest the possibility of transmission of this virus between animals between different species. One animal was found as carrier of genome fragments of two different alphacoronaviruses.
Immunotropic effects of hypoglycemic agents on coronavirus infection: a view from the perspective of pharmacogenetics
Authors: Gurevich Konstantin G. , Sorokina Yulia A. , Urakov Alexander L. , Sinyushkina Snezhana D. , Pryazhnikova Maria I. , Gorinova Alyona V. , Lovtsova Lyubov V. , Zanozina Olga V.
Published: November 2022

Diabetes mellitus is a predictor of the severe course of a new coronavirus infection and high mortality, in this regard, the selection of appropriate hypoglycemic therapy is a vital issue. In this article, we paid attention to dipeptidyl peptidase-4 (DPP-4) inhibitors, since this group of drugs has features like low risk of hyperglycemia and immuno-mediated effects. For the most effective treatment, it is necessary to take into account the individual characteristics of each patient, namely, the achievements of pharmacogenetics. The genetic variability of the response to therapy with DPP-4 inhibitors is due to a variety of polymorphisms, several main variations are considered in the review. The ambiguity of the available studies on the effectiveness of DPP-4 inhibitors in patients with type 2 diabetes with COVID-19 indicates the need to continue pharmacogenetic studies. The combination of knowledge about the subtleties of the mechanisms of pharmacological action of drugs and individual characteristics of pharmacodinamics will ensure the greatest effectiveness and safety of personalized therapy of diabetes mellitus against the background of coronavirus infection.
Emergency contraception: knowledge, attitude and awareness of its usage among medical students in a private medical college of Davangere
Authors: Chandramohan Malavika Jabin , Prabhudev Prema
Published: November 2022

Background: Emergency contraception (EC) is the contraception used to prevent pregnancy after unintended or unprotected sexual intercourse. EC can be used after contraceptive failure or misuse (as in slippage or breakage of condoms, forgotten pills). It is used before the time of implantation and prevents pregnancy in 75-99% of the cases. EC is available as pills or IUCD.Methods: A cross-sectional study involving final year medical students was conducted at SSIMS and RC, Davangere, Karnataka, India. A 32-point questionnaire encompassing the socio-demographic details, knowledge and attitude towards EC was answered by a total 146 participants. The data were entered in Microsoft excel sheet and the descriptive statistics were analysed using Epi-info softwareResults: Majority of the participants had heard about EC and also knew the trade name under which it is available. The main indication for EC usage was thought to be unprotected sex by 76% participants. Nearly 90% participants knew that EC does not protect against STDs. 85% participants thought that failures can happen despite EC usage. On assessing the attitude, majority disagreed to the notion that EC usage promotes promiscuity and using EC is a sinful act.Conclusions: Knowledge and attitude regarding EC and its usage was fairly good among the medical students in our study. The inclusion of EC in medical curriculum has added to their knowledge. Being the responsible future physicians, their knowledge with regard to EC is deemed important. Similarly, an awareness regarding EC should be spread across the general public to prevent the unwanted pregnancies and its consequences.
KİTAP DEĞERLENDİRME/BOOK REVIEW: Selim Ahmetoğlu, DEVRİM GÜNLERİNDE TRABZON II. MEŞRUTİYET, İTTİHATÇILIK VE TOPLUMSAL DÖNÜŞÜM (1908-1914).
Authors: AKSOY Volkan
Published: November 2022

KİTAP DEĞERLENDİRME/BOOK REVIEW

Selim Ahmetoğlu, DEVRİM GÜNLERİNDE TRABZON II. MEŞRUTİYET, İTTİHATÇILIK VE TOPLUMSAL DÖNÜŞÜM (1908-1914), 1. Baskı, Timaş Yayınları, İstanbul 2022, 334 s.
KİTAP DEĞERLENDİRME/BOOK REVIEW: Önder Duman, MEŞRUTİYET’TEN “BEYAZ DEVRİM”E CANİK - SAMSUN’DA SEÇİMLER VE SİYASET (1877-1950).
Authors: BAŞAR Oğuzhan
Published: November 2022

KİTAP DEĞERLENDİRME/BOOK REVIEW: Önder Duman, MEŞRUTİYET’TEN “BEYAZ DEVRİM”E CANİK - SAMSUN’DA SEÇİMLER VE SİYASET (1877-1950), Canik Belediyesi, Samsun 2015, 413 s.
The Models of Social Activity in Russia in 1917–1920
Authors:   Saratov State University, Gumenyuk A. A.
Published: November 2022

In this article the main directions of social преобразований in Russia since 1917 to 1920 was analyzed. The author has given main attention of the Public commissary of social provision. Materials on the data of the Russian legal and some publications were prepared.
The Statement of the British Administration in Quebec and the Problem of Adaptation of the Traditional Colonial Policy (the Middle of 1760th)
Authors:   Chelyabinsk State University, Nohrin I. M.
Published: November 2022

Article is devoted to studying of policy of Great Britain in Quebec in the first years after the termination of Seven-year war. The author has concentrated his attention on researching of factors of its formation: the governmental course, policy of governor-generals, the conflict of interests of English merchants and the French community. The special attention is given to a problem of formation of administration political course on the basis of struggle of «old» and «new» social groups.
Neolithization process in Euro-Asian Area Abstract
Authors:   Kalmyk State University named after B.B. Gorodovikov, Koltsov P. M.
Published: November 2022

The process of neolithization and introduction of producing forms of economics did not take place in different parts of Euro-Asia simultaneously. South Asia and South-East Asia zones are considered to be first in the selection and domestication of animals.In the Northern part of the Caspian Sea area the neolithization took place on the basis of intensification and specialization of appropriating forms of activities. Further assertion of the advanced experience of Southern focus led to the formation of cultures with pricked and dashed ceramics and micro stone industry in North Caspian Sea area. Gradually the process of assertion of new production and enrichment of rational knowledge covered both Southern steppes and forest-steppe territories penetrating deep into West Europe.
Isolated Chest Wall Tuberculosis Presenting As an Abscess
Authors: Maalouf Hani , Ghattas Souad , Saber Toufic , Malek Alexandre
Published: November 2022

Lebanon is a relatively low Tuberculosis burden country but has a high proportion of extrapulmonary tuberculosis. Tuberculosis involving the chest wall is found in around 1% of all skeletal tuberculosis cases. We present the case of an 81-year-old immunocompetent patient who presented with 3 months history of a painful lump in the anterior chest wall. PCR for MTB (mycobacterium tuberculosis) was positive and a diagnosis of the tubercular abscess of the chest wall was made mimicking a pyogenic abscess.
MOOCs as a Research Agenda: Changes Over Time
Authors: Zhang Shunan , Che ShaoPeng , Nan Dongyan , Kim Jang Hyun
Published: November 2022

MOOCs (massive open online courses) have attracted considerable attention from researchers. Fueled by constant change and developments in educational technology, the trends of MOOCs have varied greatly over the years. To detect and visualize the developments and changes in MOOC research, 4,652 articles published between 2009 and 2021 were retrieved from Web of Science and Scopus with the aid of CiteSpace. This study sought to explore the number of publications, co-citation network, cluster analysis, timeline analysis, burstness analysis, and dual-map overlays based on co-citation relationships. The first finding was that the number of publications on MOOCs had increased consistently, and grew especially quickly between 2013 and 2015. Second, the main topic of the top 10 co-cited studies revolved around the problem of learner continuance. Third, blended programs, task-technology fit, and comparative analysis have emerged as popular subjects. Fourth, the development of MOOC research has followed distinct phases, with 2009 to 2012 the starting phase, 2013 to 2015 the high growth phase, 2016 to 2018 the plateau phase, and 2019 to 2021 another peak phase. Lastly, both cluster analysis and dual-map overlays provided empirical evidence of cross-disciplinary research. Our findings provided an in-depth and dynamic understanding of the development and evolution of MOOC research and also proposed novel ideas for future studies.
Using Low-immersive Virtual Reality in Online Learning: Field Notes from Environmental Management Education
Authors: Rawson Rebecca , Okere Uchechukwu , Tooth Owen
Published: November 2022

Recent research in the field of virtual reality (VR) education is dominated by the application, experience, and effectiveness of high-immersive environments. However, high-immersive VR may not be accessible to all learners, with online distance learning students in particular unable to fully engage without being supplied with appropriate accessories. These field notes shed light on the role of low-immersive VR as a desktop tool for online distance learning students, exploring student experience of using 360° virtual spaces to undertake a summative assessment. Primary data collection in the form of an anonymous online survey was employed to gather feedback from postgraduate environmental management students who used low-immersive VR to undertake an environmental management system audit of a university campus. Quantitative results were analysed using descriptive statistics and qualitative responses using thematic analysis. Findings indicated that with guidance from the academic teaching staff and practice using the software, the majority of students felt both prepared and happy to undertake a summative assessment using VR spaces. Skills development and an appreciation of the effectiveness of the assessment approach were also highlighted as positive outcomes reinforcing findings from literature on the value of VR to improve learning outcomes particularly with practical tasks. Limitations of the assessment content and software were however noted by students, but both could be resolved with adaptations to the tool. It is hoped this research will be valuable to online education providers to demonstrate the value of using low-immersive VR within their programmes.
The Origins and Dynamics of Inflation in Turkey: An SVAR Approach
Authors: SIKLAR Emel , SIKLAR Ilyas
Published: November 2022

This study aims to present empirical evidence on the relative importance of supply and demand-side factors in determining the fluctuations in the general level of prices in the Turkish economy. The employed strategy uses the view that supply and demand pressures can be distinguished from each other depending on the direction of their effects on price and quantity. After classifying the related economic variables as supply, demand, and common factors, the main determinants of domestic supply and demand were estimated econometrically using sample data from 2003:1–2021:4, and their relative contribution to inflation was calculated. By using these basic determinants, the estimated structural vector autoregressive (SVAR) model shows that the pressures arising from the supply side are more dominant than the pressures of the demand side on the inflationary process in Turkey. The results indicate that the methodology suggested in this study will be useful in separating the factors that contribute to inflation, which has recently gotten out of control in Turkey and is gradually moving away from the targeted inflation. Policymakers considering these findings can reach optimal decisions in conducting the monetary policy toward the targeted level of inflation.
Classification of Review Text using Hybrid Convolutional Neural Network and Gated Recurrent Unit Methods
Authors: Rachim Fiqih Fathor , Damayanti Auli , Winarko Edi
Published: November 2022

Consumer reviews are opinions from buyers to sellers based on service satisfaction or product quality. The more consumer reviews cause the process of analyzing manually will be difficult. Therefore, an automated sentiment analysis system is needed. Each review will be grouped into a sentiment class which is divided into positive and negative classes. This study aims to classify review texts using the Convolutional Neural Network (CNN) and Gated Recurrent Unit (GRU) methods. The research stages in this study include collecting data on Tokopedia review texts, extracting hidden information from review texts using CNN, conducting learning on review texts using GRU. A total of 1000 review texts were divided into 80% training data and 20% test data. The review text is converted into matrix using One Hot Encoding algorithm and then extracted using CNN. The CNN process includes the convolution calculation, the calculation of the Rectified Linear Unit (ReLU) activation function, and the pooling stage. The extraction results in the CNN process are continued in the GRU process. The GRU process includes initializing parameters, GRU feed forward, Cross-Entropy Error calculation, GRU feedback, and updating weights and biases. The optimal weight is obtained when the error value in the training is less than the expected minimum error or the training iteration has reached the specified maximum iteration. Optimal weight is used for validation test on test data. The implementation of review text classification using the hybrid Convolutional Neural Network (CNN) and Gated Recurrent Unit (GRU) method was made using the python programming language. The accuracy of the validation test is 88.5%
Analisis Kestabilan dan Kontrol Optimum pada Model Penyebaran Penyakit Influenza dengan Adanya Populasi Cross-Immune
Authors: Fajar Bertha Aurellia Pamudya , Miswanto  , Windarto
Published: November 2022

Influenza is a respiratory tract infection known as flu. Caused by an RNA virus from Orthomyxoviridae family. This thesis aims to analyze the stability of the equilibrium point in the mathematical model of influenza transmission with Cross-Immune population and applying optimal control variables in the form of prevention and treatment. In this mathematical model of influenza transmission with Cross-Immune population, we obtain two equilibriums namely, the non- endemic equilibrium and the endemic equilibrium. Local stability and the existence of endemic equilibrium depend on the basic reproduction number (R0). The spread of influenza does not occur in the population when R0 < 1 and the spread of influenza persist in the population when R0 > 1. Furthermore, the problem of control variables in the mathematical model of influenza transmission is determined through the Pontryagin Maximum Principle method. The numerical simulation results show that treatment efforts are more effective in suppressing the spread of influenza disease than prevention efforts. However, giving control variables in the form of prevention and treatment at the same time is very effective in minimizing the number of human populations expose to and infected with influenza.
Penugasan Tutor Sebaya dengan Metode Pinalti
Authors: Batlajery Hardy , Ilwaru Venn
Published: November 2022

This research focuses on the assignment of peer tutors in the Mathematics Study Program, Mathematics Department, FMIPA Unpatti. The purpose of this study was to obtain the completion of peer tutor assignments with the penalty method. The penalty method is a method used to solve the problem of unbalanced assignments. The processed two parts, namely finding the initial solution and finding the optimal solution. The column penalty method or the row penalty method is used to get the initial solution. In this study, the row penalty method is used because the number of rows is less than the number of columns, and the optimal solution is sought. The data used are student names, courses, and final grades. The results obtained using the Penalty method are that David becomes a tutor in the Statistical Method course, Alfito becomes a tutor in the Operations Research course, Christin becomes a tutor in the Linear Program course, Gabriella becomes a tutor in the Analytical Geometry course and Navila becomes a tutor in the course Elementary Statistics.
The effect of the team games tournament learning model assisted by question card media on student learning outcomes
Authors: Arizka Najihan , Khairuna Khairuna
Published: November 2022

This study aimed to improve student learning outcomes and determine the effect of the Team Games Tournament (TGT) learning model assisted by question card media on human reproductive system material. This study employed a quantitative research type, with a quasi-experimental research design. Class XI science 1 student totalled 36, and class XI science 2 students totalled 36, with research instruments consisting of hand-held elective tests administered during post-test and pre-test. Using version 20 of the SPSS software, descriptive and paired simple t-test analyses of data were conducted. The average pre-test scores for the experimental group were 24.17, whereas those for the control group were 22,78. The average post-test scores of the experimental group were 80,14, on the other hand, those of the control group were 69. In the paired simple t-test, the 2-tailed sign value was 0,00 < 0,05, and the tcount > ttable which was 47,61 > 2,03. This demonstrates that the TGT learning model assisted by media question cards can enhance learning outcomes and significantly impact the biology learning process. TGT learning aided by question cards may be one way for educators to optimise learning processes and outcomes. Abstrak Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Team Games Tournament (TGT) berbantuan media question card pada materi sistem reproduksi manusia dan meningkatkan hasil belajar peserta didik SMA kelas XI IPA. Jenis penelitian berupa penelitian kuantitatif dengan desain penelitian berupa  quasi eksperimen. Sampel penelitian yaitu siswa kelas XI IPA 1 berjumlah 36 siswa dan kelas XI IPA 2 berjumlah 36 siswa dengan instrument penelitian berupa tes pilihan bergandan yang diberikan saat dilakukan uji post-test dan pre-test. Analisis data berupa analisis deskriptif dan uji paired simple t-test dengan bantuan software SPSS versi 20. Adapun hasil rata-rata pre-test pada kelas eksperimen yaitu 24,17 dan pada kelas kontrol yaitu 22,78. Hasil rata-rata post-test kelas eksperimen yaitu 80,14 dan  kelas kontrol yaitu 69,72.  Pada uji paired simple t-test nilai sig. 2-tailed 0,00 < 0,05 dengan nilai thitung > ttabel yaitu 47,61 > 2,03. Hal ini menunjukan bahwa model pembelajaran TGT berbantuan media question card dapat meningkatkan hasil belajar siswa dan juga memiliki pengaruh yang signifikan dalam proses pembelajaran biologi. Pembelajaran TGT berbantuan question card dapat menjadi salah satu solusi bagi guru untuk mengoptimalkan proses dan hasil belajar.
Development of website-based e-poster learning media on the digestive system material of class XI MA Madani Alauddin Pao-Pao students
Authors: Alamsyah Nur , Taufiq Ainul Uyuni , Rivai Andi Tenri Ola
Published: November 2022

Rapid technological advances must be used optimally, especially in compiling learning media to create effective and efficient learning activities. This research aims to develop an e-poster learning media based on a website on digestion system material for grade XI of MA Madani Alauddin Pao-Pao that is valid, practical, and effective. This research uses the ADDIE development model's type of research and development. The developed product is tested through validity, practicality, and effectiveness tests. The subjects were 27 students of grade XI MIA MA Madani Alauddin Pao-Pao. The instruments used in the study were media validation sheets, student response questionnaires, educator response questionnaires, and learning outcomes test items. The results of the data analysis obtained a validity level of 3.60 (very valid), the practicality level of student responses is 3.18 (practical), and the educators' response is 3.06 (practical). Learning outcomes test students is 88.88% (effective). Based on the research, e-poster learning media based on a website on digestion system material deserves to be used. The result of the research is in the form of teaching media. Researchers hope that students can be motivated to learn independently and that teachers can make it easier to distribute the material being taught.Abstrak Kemajuan teknologi yang kian pesat perlu dimanfaatkan secara optimal, khususnya dalam menyusun media pembelajaran sehingga tercipta kegiatan belajar yang efektif dan efisien. Penelitian ini bertujuan untuk mengembangkan media pembelajaran e-poster berbasis website pada materi sistem pencernaan siswa kelas XI MA Madani Alauddin Pao-Pao yang bersifat valid, praktis, dan efektif. Penelitian ini menggunakan jenis penelitian dan pengembangan dengan model pengembangan ADDIE. Produk yang dikembangkan diuji melalui uji validitas, uji kepraktisan dan uji keefektifan. Subjek dalam penelitian ini adalah peserta didik kelas XI MIA MA Madani Alauddin Pao-Pao sebanyak 27 orang. Instrumen yang digunakan dalam penelitian adalah lembar validasi media, angket respon peserta didik, angket respon pendidik, dan butir-butir tes hasil belajar. Hasil penelitian menunjukkan bahwa media yang dikembangkan memiliki tingkat validitas yaitu 3.60 (sangat valid), tingkat kepraktisan berdasarkan penilaian respon peserta didik yaitu 3.18 (praktis) dan respon pendidik yaitu 3.06 (praktis). Tes hasil belajar peserta didik mencapai 88.88% (efektif), sehingga media pembelajaran e-poster berbasis website layak digunakan. Hasil penelitian berupa media ajar, peneliti berharap siswa termotivasi belajar secara mandiri dan bagi guru dapat memudahkan menyalurkan materi yang diajarkan.
The effect of digital booklets “Crustaceae diversity at mangrove Sangiang Island” on students' conservation attitude using problem-based learning
Authors: Wahyuni Indria , Ratnasari Dwi , Mahrawi Mahrawi , Inayah Inayah
Published: November 2022

The rapid advancement of technology causes educators to be ready to use digital-based learning media. This study aims to determine the effect of the digital booklet on the diversity of mangrove crabs on Sangiang Island in the Problem Based Learning (PBL) model on students' conservation attitudes. This research method uses a quasi-experimental design with a post-test-only control group design. The research sample was taken using a purposive sampling technique. This study used two sample groups, namely the control and experimental groups. Data collection uses a questionnaire which is accessed via a Google form. The questionnaire contains questions about the conservation attitudes character of as many as 50 items; with a value scale from 1-4. The results showed an effect of using digital booklets on the conservation attitude of students at SMA Negeri 4 Serang City. The average conservation attitude in the experimental class got a fairly high score of 55, while the control class got a score of 54. This value is the result of the accumulation of five characteristics of attainment of conservation attitudes, namely knowledge, concern, skills, attitudes, and participation. Based on these results, using digital media, one of which is a booklet, can be a solution for achieving the competence of students' conservation attitudes.Abstrak Pesatnya kemajuan teknologi menyebabkan para pendidik harus siap memanfaatkan media pembelajaran berbasis digital. Penelitian ini bertujuan untuk mengetahui pengaruh booklet digital keanekaragaman kepiting bakau di pulau Sangiang dengan model Problem Based Learning (PBL) terhadap sikap konservasi siswa. Metode penelitian ini menggunakan quasi experiment dengan rancangan post-test only control group design. Pengambilan sampel penelitian menggunakan teknik purposive sampling. Penelitian ini menggunakan dua kelompok sampel yaitu kelompok kontrol dan eksperimen. Pengumpulan data menggunakan angket yang diakses melalui Google form. Angket berisi pertanyaan tentang karakter sikap konservasi sebanyak 50 butir soal, dan dilengkapi dengan skala nilai dari 1-4. Hasil penelitian menunjukkan adanya pengaruh penggunaan booklet digital terhadap sikap konservasi siswa di SMA Negeri 4 Kota Serang. Rata-rata sikap konservasi di kelas eksperimen mendapatkan nilai yang cukup tinggi yaitu sebesar 55 sedangkan untuk kelas kontrol memperoleh nilai 54. Nilai tersebut adalah hasil akumulasi dari lima karakter ketercapaian sikap konservasi yaitu pengetahuan, kepedulian, keterampilan, sikap, dan partisipasi. Berdasarkan hasil tersebut, penggunaan media digital salah satunya berbentuk booklet dapat menjadi solusi untuk ketercapaian kompetensi sikap konservasi peserta didik.
WORK ANALYSIS OF HYDRAULIC STATIC PILE DRIVER EQUIPMENT ON PILE FOUNDATION WORK IN TERMS OF TIME AND COST
Authors: Azhar Abnu , Eliatun Eliatun
Published: November 2022

To make a building requires a strong foundation to withstand the load on it. the Physical Work Project, Renovation and Expansion of the District Court Building requires heavy equipment management in the form of piles, the piling method used is the Hydraulic Static Pile Driver. The pile management is needed to find out the estimated working time on the entire building so that the implementation goes according to or does not exceed the planned project time. Therefore, it is necessary to analyze the efficiency of the piling tool. The results of the descriptive analysis in this study obtained the production value of the Hydraulic Static Pile Driver tool. The highest production value was 0.23 meters/minute, and the lowest value was 0.21 meters/minute. The time required to complete the project erection work based on the planning is nine weeks, while the realization in the field to complete it in seven weeks. The planned implementation cost to complete the erection work for this project is Rp. 2,073,360,000. Meanwhile, the cost of field realization is Rp. 2,481,150,000. this means that the implementation costs in the field are greater than the planning costs of Rp. 407,790,000 this was due to the addition of 828.00 m3 of pile procurement volume and 828 m3 of piling and handling work, and 138 nos of pile connections.
IMPLEMENTATION OF 4D BUILDING INFORMATION MODELING (BIM) ON THE FLAT BUILDING PROJECT OF BBPJN XI/PJN I KALIMANTAN
Authors: Hafizurahman Akhmad , Khatimi Husnul
Published: November 2022

The BBPJN XI/PJN I Kalimantan Flats construction project only applies manual scheduling in the form of an S curve. This building consists of 9 floors with reinforced concrete material. Currently, there is BIM technology that can minimize problems caused by manual scheduling in controlling time. So in this study, a study will be conducted on the application of 4D BIM-based project scheduling using the Tekla Structures 2020 software from manual project scheduling.The building modeling refers to the plan drawings, including piling and reinforced concrete structural work in the Tekla Structures 2020 software. Scheduling is made using the Task Manager extension found in Tekla referring to the RAB, S curve, and interviews with the project party. The modeling results are then inputted into the Task Manager to provide 4D visualization with the help of the Object Representation extension combined with the Project Status Visualization extension.Based on the results of monitoring project progress (tracking) inputted into the Task Manager, it is known that lower structural work was completed two weeks earlier. Upper structural work started from the ground floor starting one week earlier, and all structural work was completed 16 days earlier than scheduled plan. The duration of the work generated by Tekla Structures 2020 is 126 calendar days. The work starts from October 19, 2020, to February 21, 2021. So, with several extensions owned by Tekla, it can be said that the use of Tekla Structures 2020 software in the implementation of 4D BIM can be relied on for monitoring and minimizing errors in scheduling.
COMPARISON OF THE EFFECTIVENESS OF BUILDING INFORMATION MODELING BASED COST ESTIMATION AGAINST THE CONTRACTOR'S COST BUDGET PLAN IN DEVELOPMENT PROJECT OF BANJARBARU BAUNTUNG MARKET
Authors: Adipratama Muhammad Hanugrah , Khatimi Husnul
Published: November 2022

This study focuses on the use of Building Information Modeling (BIM) which begins with creating a 3D digital model (virtual building) which serves as a means for planning, designing, implementing development, and maintaining the building and its infrastructure for all parties involved in the project. Unlike other studies that use concrete structures, this study refers to the Bauntung Banjarbaru Market building with a steel structure. BIM software program is specific and correct. Specific is within the use of BIM information is taken and adapted to real conditions within the area. Correct is a constructible model, that is, the model that is created is the same as the model that was constructed. Besides, when there is a change in the model, the resulting cost estimate can change automatically.Modeling of building structures includes modeling of reinforced concrete structures and steel structures. The modeling is done using a software called Tekla Structures with a South-East Asia environment that refers to the plan drawing. After the modeling is complete, the work unit price is inputted into the software. The output of this modeling is direct cost estimation for structural work. For manual cost estimation using cost budget plan that has been obtained from the contractor in the form of a Microsoft Excel file.From the results of the analysis of the two cost estimates, the resulting comparison of the cost difference is quite scanty. The difference between manual cost estimation and BIM based cost estimation is 0.26%. So, it can be concluded that the use of BIM based cost estimation can be used because it produces cost estimates that are faster than using manual calculations made by contractors.The use of BIM can reduce costs and inaccuracies in the calculation of estimates in projects because it can be done more thoroughly. Keywords: BIM-based cost estimation, Tekla Structures, building structures
PENGARUH MANAJEMEN PERILAKU KOMBINASI TELL-SHOW-DO DAN PENGGUNAAN GAME SMARTPHONE SEBELUM PROSEDUR PERAWATAN GIGI TERHADAP TINGKAT KECEMASAN DENTAL ANAK (Literature Review)
Authors: Maharani Sonia Dewi , Dewi Nurdiana , Wardani Ika Kusuma
Published: November 2022

ABSTRACTBackground : Anxiety and fear are factors that influence children's emotions so that they are less cooperative during dental treatment process. Non-pharmacological methods can be used to overcome these problems, such as by tell-show-do, modeling, enhancing control, voice control, behavior formation, distraction, and magic tricks. Smartphone game applications are very popular among children since it provides an overview of the dental care experience through various features available in it.Objective: To determine the effect of tell-show-do combination behavior management and the use of smartphone games before dental procedures on children's dental anxiety levels. Method: This research was literature review. Literature searches were performed through PubMed, Science Direct, and Google Scholar.Results: There are 30 journals that meet the inclusion criteria, that are journals published in 2015-2020, written in Indonesian and English, using objects of children aged 6-12 years, and available in full text. The main interventions reviewed in the journal are the used of tell-show-do behavior management and game dentistry in smart phone. Conslusion:The combination of tell-show-do behavior management and the use of smart phone games had an effect on reducing children's anxiety levels.Keywords:  Behavior Management, Children Dental Anxiety, Game, Smartphone,Tell-Show-DoABSTRAKLatar Belakang: Rasa cemas dan takut menjadi salah satu faktor yang mempengaruhi emosi anak sehingga kurang kooperatif selama proses perawatan ketika berkunjung ke dokter gigi. Terdapat metode nonfarmakologi yang dapat diberikan untuk menangani kecemasan anak, yaitu tell-show-do, modelling, meningkatkan kontrol, kontrol suara, pembentukan perilaku, distraksi, dan trik sulap. Aplikasi game smartphone sangat disukai anak-anak karena dapat memberikan gambaran pengalaman perawatan gigi dari berbagai fitur yang tersedia di aplikasi tersebut. Tujuan: Mengetahui pengaruh manajemen perilaku kombinasi tell-show-do dan penggunaan game smartphone sebelum prosedur perawatan gigi terhadap tingkat kecemasan dental anak. Metode: Menggunakan metode literature review atau tinjauan pustaka. Penelusuran literatur dilakukan menggunakan PubMed, Science Direct, dan Google Scholar.  Hasil: Didapatkan 30 jurnal yang memenuhi kriteria inklusi yaitu jurnal yang terbit pada tahun 2015-2020, jurnal berbahasa Indonesia dan Inggris, jurnal dengan subjek anak-anak usia 6-12 tahun, jurnal tersedia dalam bentuk full text, intervensi utama yang ditelaah pada jurnal adalah penggunaan manajemen perilaku tell-show-do dan dentist game smartphone. Kesimpulan: Manajemen perilaku kombinasi tell-show-do dan penggunaan game smartphone berpengaruh dalam menurunkan tingkat kecemasan anak.Kata kunci : Game, Kecemasan Dental Anak, Manajemen Perilaku, Smartphone, Tell-Show-Do
PENGARUH PERENDAMAN KITOSAN SISIK IKAN HARUAN (Channa striata) TERHADAP STRUKTUR EMAIL GIGI
Authors: Balad Duhan Kanzu , Tri Putri Deby Kania , Oktiani Beta Widya
Published: November 2022

ABSTRACTBackground: Acidic water from South Borneo peat land is one of the causes of enamel structure damage. Haruan fish (Channa striata) have scales that can be processed into chitosan. Chitosan contains amino and hydroxyl groups react with acid ions, increasing the environment pH and interfering the demineralization process. Purpose: To determine immersion effect of haruan fish scales chitosan on tooth enamel structure. Method: The research design was true experimental post test only with control group design. The treatment consisted of 4 groups, group I was the baseline, group II was the negative control group of teeth immersed in phosphoric acid 5.2 pH, groups III and IV were groups of teeth soaked with phosphoric acid 5.2 pH and chitosan solution with a concentration 2.5% and 5%. Data results were in the form of images from the buccal enamel surface observed with Scanning Electron Microscope. Results: Group III with 2.5% concentration of chitosan solution had less damage to enamel surface than negative control, and group IV with solution 5% chitosan concentration showed no damage and had better visualization than baseline group. Conclusion: Haruan fish scales chitosan has been shown to inhibit tooth enamel demineralization and play role in tooth remineralization process. Keywords :     Chitosan, Demineralization, Enamel, Haruan Fish Scales, SEM. ABSTRAKLatar Belakang: Air dari lahan rawa gambut Kalimantan Selatan yang bersifat asam merupakan salah satu penyebab kerusakan struktur email gigi. Ikan haruan (Channa striata) memiliki sisik yang dapat diolah menjadi kitosan. Kitosan mengandung gugus amino dan hidroksil bereaksi dengan ion-ion asam, meningkatkan pH lingkungan serta menghambat proses demineralisasi. Tujuan: Untuk mengetahui pengaruh perendaman kitosan sisik ikan haruan terhadap struktur email gigi. Metode: Desain penelitian true experimental post test only with control group design. Perlakuan terdiri dari 4 kelompok, kelompok I sebagai baseline, kelompok II adalah kelompok gigi yang direndam dengan asam fosfat 5,2 pH sebagai kontrol negatif, kelompok III dan IV adalah kelompok gigi yang direndam dengan asam fosfat 5,2 pH dan larutan kitosan dengan konsentrasi 2,5% dan 5% dan data berupa gambar dari hasil pengamatan permukaan email pada bagian bukal dengan Scanning Electron Microscope. Hasil: Kelompok III dengan larutan kitosan konsentrasi 2,5% memiliki kerusakan permukaan email lebih minimal daripada kontrol negatif, dan kelompok IV dengan larutan kitosan konsentrasi 5% tidak menunjukkan kerusakan dan memiliki visualisasi yang lebih baik daripada kelompok baseline. Kesimpulan: Kitosan sisik ikan Haruan telah terbukti dapat menghambat demineralisasi email gigi dan berperan dalam proses remineralisasi gigi. Kata kunci :  Demineralisasi, Email, Kitosan, SEM, Sisik Ikan Haruan.
PENGARUH EKSTRAK DAUN KARAMUNTING (Rhodomyrtus tomentosa) TERHADAP JUMLAH SEL NAUTROFIL PADA PULPA
Authors: Dahliani Reisa , Ichrom Nahzi Muhammad Yanuar , Setyawardhana Raden Harry Dharmawan
Published: November 2022

ABSTRACTBackground: Caramunting leaf (Rhodomyrtus tomentosa) is an alternative pulp capping material that can provide anti-inflammatory effects. Phytochemical screening showed that caramunting leaf has secondary metabolites that inhibit oxidant production by neutrophils, monocytes, and macrophages. The decrease in inflammatory activity was marked by a decrease in the number of neutrophils on 3rd day as the inflammatory process decreased. Purpose: To determine and analyze the effect of Karamunting leaf extract (Rhodomyrtus tomentosa) at the dose of 800mg/KgBB on the neutrophil number in pulp inflammation of Wistar rats on 1st and 3rd day. Methods: This study was true experimental research (post-test only with control group design) using 30 Wistar rats divided into 6 groups which were given pulp capping material on the 1st and 3rd day using calcium hydroxide, Karamunting leaf extract, and without pulp capping material. The number of neutrophils was observed microscopically on the 1st and 3rd day. Results: One-way ANOVA and Post hoc Bonferroni test showed significant differences (p<0.05) in all groups. Conclusion: The administration of Karamunting leaf extract (Rhodomyrtus tomentosa) at the dose of 800mg/KgBB had a significant effect on reducing the neutrophil number in pulp inflammation of Wistar rats on 1st and 3rd day. Keywords: Karamunting leaf (Rhodomyrtus tomentosa), neutrophils, pulp capping. ABSTRAKLatar Belakang: Daun Karamunting (Rhodomyrtus tomentosa) merupakan salah satu bahan alternatif pulp capping yang dapat memberikan efek antiinflamasi. Skrining fitokimia menunjukan daun karamunting memiliki metabolit sekunder yang menghambat produksi oksidan oleh neutrofil, monosit dan makrofag. Penurunan aktivitas inflamasi salah satunya ditandai oleh penurunan jumlah neutrofil dihari ke-3 seiring berkurangnya proses inflamasi. Tujuan: Mengetahui dan menganalisis pengaruh pemberian ekstrak daun karamunting (Rhodomyrtus tomentosa) dosis 800mg/KgBB terhadap jumlah sel neutrofil pada inflamasi pulpa tikus wistar di hari ke-1 dan ke-3. Metode: Penelitian ini merupakan penelitian eksperimental murni dengan rancangan post-test only with control group design menggunakan 30 ekor tikus wistar dibagi menjadi 6 kelompok yang akan diberikan bahan pulp capping pada hari ke-1 dan ke-3 menggunakan kalsium hidroksida, ekstrak daun karamunting, dan tanpa pemberian bahan pulp capping. Jumlah neutrofil diamati secara mikroskopis di hari ke-1 dan hari ke-3. Hasil: One-way Anova dan Post hoc bonferroni menunjukkan perbedaan bermakna (p<0,05) pada semua kelompok. Kesimpulan: Pemberian ekstrak daun karamunting (Rhodomyrtus tomentosa) dosis 800mg/KgBB memberikan pengaruh yang signifikan terhadap penurunan jumlah sel neutrofil pada inflamasi pulpa tikus wistar di hari ke-1 dan ke-3. Kata kunci : daun karamunting (Rhodomyrtus tomentosa), neutrophil, pulp capping.
HUBUNGAN PENGETAHUAN DAN SIKAP IBU TENTANG KESEHATAN GIGI DAN MULUT TERHADAP TINGKAT KEPARAHAN EARLY CHILDHOOD CARIES PADA BALITA (Literature Review)
Authors: Ahmad Anandita , Azizah Aulia , Dewi Renie Kumala
Published: November 2022

ABSTRACT Background: Cases of Early Childhood Caries (ECC) are recognized as a significant health problem. ECC can cause health complications in children such as persistent pain, loss of appetite, difficulty eating and abscesses. WHO data in 2018 states that there are 60% -90% of caries cases that occur in children. Many parents, especially mothers, are still not aware that maintaining healthy teeth and mouth is important. Objective: To find out how the level of knowledge and attitudes of mothers about oral health on the severity of ECC in early childhood are related. Methods: The method used in this study is a literature review with a narrative review procedure. Results: The results of the review of the articles stated that mother's knowledge was in the good category, mother's attitude was in the positive category and ECC conditions in children under five based on def-t included in the high category. Conclusion: There is a correlation between knowledge and attitudes of mothers about oral health on early childhood caries in children under five.Keywords: Early childhood caries, Mother’s attitude, Mother’s knowledge.ABSTRAKLatar Belakang: Early Childhood Caries (ECC) dikenal sebagai masalah kesehatan yang signifikan. ECC dapat menimbulkan komplikasi kesehatan pada anak seperti nyeri yang persisten, kehilangan nafsu makan, kesulitan makan dan abses. Data WHO tahun 2018 menyebutkan ada 60%-90% kasus karies yang terjadi pada anak-anak. Orang tua terutama ibu masih banyak yang belum menyadari bahwa menjaga kesehatan gigi dan mulut adalah hal yang penting. Tujuan: Untuk mengetahui bagaimana hubungan tingkat pengetahuan dan sikap ibu tentang kesehatan gigi dan mulut terhadap tingkat keparahan ECC pada balita. Metode: Metode penelitian ini adalah literature review dengan prosedur narative review. Hasil: Mayoritas pengetahuan ibu masuk dalam kategori kurang baik, mayoritas sikap ibu masuk dalam kategori negatif dan kejadian ECC berdasarkan indeks def-t masuk dalam kategori tinggi. Kesimpulan: Terdapat hubungan antara pengetahuan dan sikap ibu tentang kesehatan gigi dan mulut terhadap early childhood caries pada anak balita.Kata kunci: Early childhood caries, Pengetahuan ibu, Sikap ibu.