bluuebunny/crossref_metadata_2025 huggingface dataset:
Manufacture of Activated Carbon Adsorbents from Jackfruit Waste for Removal of Heavy Metals and Dyes from Wastewater: A Review
Authors: Tran Kim Ngan Thi , Hoang Bich Ngoc , Nguyen Kim Oanh Thi , Nguyen Hong Tham Thi , Phung Sy Chi , Do Huong Tra , Ngo Cam Quyen Thi
Published: April 2022

: Jackfruit is a fruit tree species distributed mainly in Southeast Asia and Brazil. The pulp and skin of jackfruit are widely used in various fields such as food, medicine, and interior decoration. However, the jackfruit processing into edible and usable products generates a large quantity of agricultural waste. In this review, we focused on summarizing the environmental applications of jackfruit waste in wastewater treatment. Specifically, the potential and application of activated carbon synthesized from jackfruit waste were assessed concerning the adsorption of organic dyes and metals from wastewater. In practical water treatment applications, the adsorption kinetic and isothermal models have been evaluated for activated carbon's suitability and adsorption capacity. This study acts as the basis for further development of the by-product materials to environmental treatment application and to reduce the negative impact of agricultural by-products on the environment.
Computational Design of Nanobody Binding to Cortisol to Improve Their Binding Affinity Using Molecular Docking and Molecular Dynamics Simulations
Authors: Baroroh Umi , Setiani Nur Asni , Mardiah Irma , Astriany Dewi , Yusuf Muhammad
Published: April 2022

Currently, nanobody binding cortisol has been deposited in the database. Unfortunately, the affinity is still in micromolar order. Substituting hydrophobic residues in the binding pocket and utilizing CDR2 and CDR3 is the strategy to improve the affinity. A single and double substitution at positions 53 and 101 have been introduced to the nanobody structure through molecular modeling. The affinity toward cortisol was evaluated using molecular docking to get the binding pose. The highest binding energy pose was used as the initial coordinate to analyze further using 100 ns molecular dynamics simulations. The binding affinities calculated by MMGBSA showed that MT3, MT5, and MT6 have better binding affinity than WT. In contrast, the ligand movement through MD simulations reveals that MT1, MT3, and MT5 are relatively stable. Hence, docking and MD simulations showed that MT3 is the best mutant than others. This mutant is substituting the threonine to isoleucine at position 53. New hydrophobic interactions occurred and caused the increase of binding. Eventually, this study provides valuable structural information to improve the binding affinity of nanobody binding cortisol for further development of this molecule to antibody-based biosensor design.
Carl Jung and Education
Authors: Murphy Rich
Published: April 2022

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Does STEM Education Make a difference to Students’ Views of Nature of Science? A Survey in Elementary Schools
Authors: Tian Saiqi , Chen Yinyan , Zhu Jinxing
Published: April 2022

This study aims to examine views of Nature of Science (VNOS) among elementary students, and to determine if STEM education make a difference to their VNOS. Data for this study was gathered from two elementary schools in China. One has never implemented STEM education. The other one implements STEM education as a course once or twice a week for students at different grades. Participants’ VNOS was gathered through responses to Likert scale questions from the Nature of Science “Mars Mission” questionnaire. Some students and their teachers were interviewed after questionnaire survey. It was found that students who have been received STEM education show higher score of VNOS than who have never been exposed to STEM education. In different dimensions, STEM education makes a significant difference to scientific worldview, and makes a difference to scientific inquiry as well as scientific enterprise. For students never received STEM education, no relation was found between grade and their VNOS. With regards to students regularly exposed to STEM education, grade shows a strong positive relation with their VNOS. The earlier students contact with STEM education, the better their view of the nature of science.
Desbalance del sistema antioxidante causado por la exposición a nanopartículas de óxido de zinc y óxido de cobre
Authors: Geraldo León Jesus Alberto , Vázquez-Duhalt Rafael , Juárez Moreno Karla Oyuky
Published: April 2022

Los nanomateriales (NM) sintetizados a partir de óxidos metálicos, como las nanopartículas de óxido de zinc (NPsZnO), son uno de los más utilizados en la industria alimentaria como recubrimientos para envases de alimentos y excipientes, y dentro de la industria cosmética en la fabricación de cremas, protectores solares, maquillajes y otros productos de belleza. Al incrementar su uso, también aumentan los escenarios de exposición y potencial efecto a la salud. El interés por estudiar sus posibles efectos tóxicos y el impacto en el ambiente se ha incrementado por consecuencia. La via de exposición y las propiedades fisicoquímicas del NM define sus interacciones moleculares y toxicidad. Los NM que ingresan a la célula interactuan con diferentes organelos, induciendo estrés oxidativo e incrementando la producción de especies de oxígeno altamente reactivas (ROS), siendo este uno de los mecanismos de nanotoxicidad mas frecuentes. Independientemente de la existencia de muchos estudios sobre la generación de ROS por las NPs, poca atención se ha dedicado a conocer si las NPs son capaces de alterar el sistema antioxidante de la célula. En este trabajo mostramos algunos ejemplos de cómo las NPsZnO y CuO, alteran las funciones antioxidantes de los hepatocitos para brindar elementos que ayuden a explicar los mecanismos moleculares de la toxicidad celular inducida por NPs.
Nanopartículas incorporadas al PMMA y sus propiedades antimicrobianas: una revisión sistemática
Authors: Lango-López Diana Guadalupe , Mireles-Ramírez Jennifer , Flores-Castro Neslie Jimena , Moreno-Fonseca María Valeria , Mendoza-Sánchez Ángela Araceli , Chávez-Granados Patricia Alejandra , Manisekaran Ravichandran
Published: April 2022

El polimetilmetacrilato (PMMA) es uno de los materiales más conocidos en la fabricación de prótesis e implantes dentales, con propiedades óptimas para su aplicación odontológica debido a las características favorecedoras como son: buena estética, biocompatibilidad, bajo nivel de absorción en agua, ser transparente, ligero y fuerte. Pese a todas estas beneficiosas propiedades, se considera que posee desventajas que se verían mejoradas con la adición de nanopartículas de distintos materiales. En la presente revisión sistemática, se identifica como problema principal la adhesión microbiana al PMMA cuando este se encuentra en cavidad oral. El objetivo se centró en comparar el uso de las nanopartículas (NPs) de diferentes metales (plata – Ag y cobre – Cu) así como de fosfato de magnesio – MgP, con el PMMA. Dentro de los principales resultados, la mayoría de los artículos mostraron efectos antimicrobianos positivos o mejorados en comparación con el PMMA convencional.
IoT Based Temperature and Soil Monitoring System with Motor Pump Control
Authors: Ghumatkar Rutuja S. , Hulbatte Megha K. , Gaikwad Mohini M. , Gurav Mrs. R. B.
Published: April 2022

Abstract: To serve the humanity nowadays technology is playing an exquisite role and a man’s basic and first need is food indeed. It will be said that about over 85% of individuals of India are directly, indirectly relied on agriculture. Proper irrigation by pump can not be maintained because of frequent power outages, unavailability of grid lines in remote areas and scarcity/cost of fuel to run pumps. to create the sustainable irrigation system and field monitoring system for convalescing crops growth also as best production, this IOT based Automatic irrigation system is proposed. during this system IOT and WSN are wont to control and monitor the irrigation system. IOT is employed to get stored data monitoring and real time monitoring of varied contents of soil. WSN is employed to create a totally wireless system to form a user-friendly system to cultivate and irrigate water properly to the sphere. Different types of sensors are used. This report presents a totally automated drip irrigation system which is controlled and monitored by using “Thinks peak Cloud Server”. Temperature and also the humidity content of the soil are frequently monitored. The system informs user about any abnormal conditions like less moisture content and temperature rise, even concentration of water by sending notifications through the wireless module.
Calidad de la atención en salud en ataque cerebrovascular en un hospital de referencia en Colombia
Authors: Martfnez-Villota Viviana Alexandra , Bernal-Bastidas Bertha Ligia , Bernal-Bastidas Wiston Vicente , Miramag-Cánchala Johnny Alexander , Mera-Martínez Paulo Francisco , Cuenca-Valencia María Fernanda , Guerrero-Montero Aída Gabriela , Portillo-Miño José Darío
Published: April 2022

INTRODUCCIÓN:
La evaluación de la calidad de la atención del ataque cerebrovascular (ACV) es una prioridad para los sistemas de salud, debido a su relación con la disminución de la discapacidad y la muerte. En este estudio se analizan los marcadores de calidad en ACV en un hospital de referencia en Nariño, Colombia.

OBJETIVO:
Evaluar los marcadores de calidad de atención en ACV en el Hospital Universitario Departamental de Nariño E. S. E., entre junio del 2018 y diciembre del 2019. Como referencia se comparó con los registros de Colombia en la plataforma RES-Q.

MATERIALES Y MÉTODOS:
Estudio descriptivo retrospectivo de pacientes con ACV atendidos intrahospitalariamente. La recolección de datos se realizó mediante la plataforma RES-Q, en tanto que el análisis se efectuó por medio de estadísticos descriptivos y frecuencias absolutas y relativas y las diferencias con pruebas analíticas.

RESULTADOS:
Se evaluaron 457 pacientes con predominio de ACV isquémico y se llevó a cabo trombólisis endovenosa al 7,2% en el 2018 y al 9,2 % en el 2019, el 27,7 % con tiempo puerta aguja menor a 60 minutos en el 2018 y el 42,8 % en el 2019. Entre los marcadores de calidad, se encontró mejoría en realización de NIHSS, evaluación de disfagia en las primeras 24 horas, realización de doppler carotideo en los primeros siete días. En comparación con Colombia, se encontró un porcentaje inferior en trombólisis endovenosa y trombectomía. La mayoría de los indicadores de atención en ACV es similar al promedio nacional.

CONCLUSIONES:
La mejoría en el cumplimiento de marcadores de calidad en ACV refleja el impacto de programas de atención en ACV. El monitoreo de los parámetros de calidad permite generar programas para fortalecer la atención integral del ataque cerebrovascular en la región.
ensino remoto de Educação Física em narrativa
Authors: Leite Leilane Shamara Guedes Pereira , Costa Alan Queiroz da , Oliveira Marcio Romeu Ribas de , Araújo Allyson Carvalho de
Published: April 2022

A literatura tem apostado na compreensão coevolutiva entre tecnologia e educação destacando o professor como peça-chave neste processo. O objetivo do texto é problematizar a vivência pedagógica de uma professora de Educação Física da rede estadual de ensino durante a pandemia de covid-19, sob as lentes do neotecnicismo e das literacias emergentes. Adotou-se a metodologia qualitativa a partir dos estudos narrativos, dos casos pedagógicos e suas contribuições para formação docente. Como resultados percebeu-se o sentimento de incompetência para lidar com plataformas digitais, o apoio de uma rede de colaboração por pares, a urgência do “como utilizar ferramentas tecnológicas” e, em segundo plano, “o que ensinar”. Considera-se, por fim, que pensar o ensino remoto de Educação Física na pandemia é mais do que pensar em tecnologia, mas antes é refletir sobre como o professor se forma pela experiência e as possibilidades de modificação na percepção de aula de Educação Física neste contexto.
Atividade física para saúde, Covid-19 e mídias sociais:
Authors: Parris Zac , Cale Lorraine , Harris Jo , Casey Ashley
Published: April 2022

Este estudo concentra-se no uso de mídias sociais por professores de Educação Física (EF) para o ensino de atividade física para saúde durante a pandemia de covid–19. Com base na pesquisa apreciativa e utilizando uma metodologia de teoria fundamentada em dados (Grounded Theory), a análise de duas entrevistas e uma tarefa digital permitem apresentar três principais temas: (1) Mídias Sociais como Ferramenta de Ensino; (2) Um Legado Digital Duradouro?, e; (3) Desigualdade do Aprendizado Remoto. Esses temas destacam a urgência em utilizar mídias sociais quando os espaços físicos da EF foram removidos, o reconhecimento de que o ensino poderia ser diferente no futuro e os desafios inerentes aos espaços digitais. Em conclusão: (1) defendemos a efetiva formação inicial e continuada de professores e no uso positivo de tecnologias digitais; (2) sugerimos que atividades on-line futuras incorporadas ao aprendizado, e; (3) exigir aos governos ações para nivelar as desigualdades tecnológicas.
Virtually learning
Authors: Ovens Alan Patrick , Philpot Rod , Bennett Blake
Published: April 2022

This paper reports on the first phase of a three-year project in which we explored ways to adapt and evolve our pedagogies in relation to the use of new and emerging digital technologies. Our aim is to develop a shared understanding and resourcefulness for teaching in an age where pedagogy in a university setting is an increasingly complex and novel problem. We focus specifically on our experiences of emergency remote teaching (ERT) where we pivoted mid semester from on-campus classroom-based teaching to exclusively online delivery and assessment. Through a dialogical approach enabled by the self-study, we support each other, describe the key challenges we have experienced, and identify the key assumptions that underpin our practices as teachers in digital learning contexts. The themes found in this dialectical relationship were named as: the visibility of students, the constraints of technology, and the fact that we are neophyte lecturers again.
enseñanza de la Educación Física
Authors: Rodriguez Victor Amar
Published: April 2022

El covid ha modificado la cotidianeidad de una estudiante de magisterio (en la mención de educación física), su forma de aprender y relación con las tecnologías. La metodologia será la cualitativa-narrativa, con el propósito de conocer y compreender el parecer de Pao. Mientras que los resultados evidencian su pasión por el fútbol sala feminino, además de mantener una alta estima a la educación como factor de transformación social y ve en las tecnologías un acicate para el cambio y mejora docente, para su autoformación y la necesidad de atender al currículo de manera más abierta y flexible. Ella presenta a la familia, como un valor para la educación de los menores, o la educación física, como una posibilidad para dar respuesta al sedentarismo o la obesidad.
Relationships to knowledge and (self)educative experiences in Physical Education
Authors: Venâncio Luciana , Sanches Neto Luiz , Charlot Bernard , Craig Cheryl J.
Published: April 2022

Although new forms of media and technology have contributed to teaching and learning in Physical Education Teacher Education (PETE) since the turn of this century, an abrupt expansion in the use of interactive technologies occurred more recently due to the need for social distancing on a global scale because of the Covid-19 (SARS-CoV-2) pandemic. In the Brazilian context, pedagogical relationships became mediated synchronously and asynchronously via online platforms. This reconfiguration restricted movement-related experiences in Physical Education, which affected the diversity of students’ embodiment of knowledge and their relationships to knowledge as “subject-bodies”. We understand that there is an anthropological foundation in the theory of the relationship to knowledge — pointed out by Charlot (2020) — that comes close to the anthropological demands explained by Daolio (2001) in Physical Education.
Miscibility in blended approaches to PETE practice
Authors: Fletcher Tim , Melvold Hordvik Mats
Published: April 2022

In this paper, we discuss findings from a collaborative self-study we conducted on enacting a blended approach (i.e. consisting of online and in-person components) to a Physical Education Teacher Education (PETE) course. Data consisted of reflective journals and recorded conversations. We examine assumptions about the structure, content, and pedagogies of “blended” approaches using the metaphor of miscibility, where liquids mix to form a homogeneous solution. The blended PETE course was not conceptualized or enacted in a way that made it miscible (i.e. it was immiscible), in that the in-person and online components were viewed as separate entities. This meant there were missed opportunities to offer formative experiences from one format to shape experiences in the other. Following the pandemic it will be important to consider the strengths of both in-person and online formats so that students experience the ways one can benefit the other.
Application of the Pediatric Early Warning Score in predicting the severity of influenza
Authors: Zhou Yuanlin , Liu Li , Shang Jin , Wen Xiaobin , Shen Xiaojia , Liu Yan , Tang Lin , Li Qian , Gan Jingqiu
Published: April 2022

Objectives: Influenza is a rapidly spreading acute respiratory
infectious disease. This disease has a high prevalence and morbidity.
Patients with critical influenza require timely admission. Identifying
patients with critical influenza and ensuring early admission for such
patients is important. The pediatric early warning score (PEWS) is
useful for the timely recognition of critical illnesses. However,
evidence supporting the efficacy of the PEWS in assessing critical
influenza is limited. This study aimed to explore the usefulness of the
PEWS as a predictive tool for critical influenza. Methods: One hundred
pediatric patients with influenza were included into this study. Their
PEWS scores were measured at the emergency department. Unconditional
logistic regression was conducted to investigate the association of each
parameter between the mildand critical influenza groups. The PEWS and
parameters were compared. Receiver operating characteristic (ROC) curves
were analyzed. Results: The difference in the PEWS and mean corpuscular
hemoglobin (MCH) levels were significantly different between the two
groups. Combinations of the PEWS and MCH achieved an R score of 0.501;
the square of the R score was 0.2506, and the area under the curve was
0.791 with a cut-off value of 0.4118. The score of the predictive model
made up of the PEWS and MCH was: 2.035+0.18*PEWS-0.073*MCH. When the
score was higher than 0.4118, the patients tended to have critical
influenza. Conclusion: Our predictive model is helpful in the
identification of patients with critical influenza; this will help in
ensuring timely admission of such cases, and thereby improving their
outcomes.
The Serbian version of the Brunnsviken brief quality of life scale: reliability, validity, and psychometric features among the population of high school students
Authors: Pantic Milica , Rancic Nemanja , Djokovic Danijela , Mihajlovic Goran
Published: April 2022

Background/Aim. Measuring the quality of life (QoL) is vital in daily clinical practice because it shows significant in-formation in addition to symptoms. There are a large number of scales for assessing the QoL. The Brunnsviken Brief Quality of Life scale (BBQ) measures importance-adjusted satisfaction across six life areas. A validation study of the BBQ scale showed good questionnaire features (high con-current and convergent validity, internal and test-retest reliability, and sensitivity to change). Therefore, the BBQ scale is excellent for use in psychiatric patients to measure outcomes, as well as for everyday screening. Methods. This prospective cross-sectional study was performed among the final-year students in five high schools in Kragujevac, Serbia. Students completed the BBQ questionnaire. Statistical analysis was performed using a standard statistical method for scale validation and standardization. Results. Our study showed that the BBQ scale had high internal consistency (Cronbach?s alpha = 0.687). That result showed that the scale had good reliability in our study. The average BBQ score was 69.63 ? 16.70 (male: 69.66 ? 18.46; female: 69.83 ? 15.78, p = 0.944). Conclusion. The Serbian version of BBQ satisfies all the criteria of successful validation. There-fore, this scale can be helpful in assessing the QoL in the healthy youth population in Serbia.
Risk factors for cerebral palsy
Authors: Demesi-Drljan Cila , Mikov Aleksandra , Krasnik Rastislava , Knezevic Aleksandar , Zvekic-Svorcan Jelena , Mikov Igor
Published: April 2022

Background/Aim. Cerebral palsy (CP) etiology is multi-factorial and heterogeneous, manifesting as damage to the developing brain. The associated risk factors can arise in the prenatal, perinatal, or postnatal period. The aim of this study was to determine the risk factors for CP and examine the associations between CP type, gestational age, and perinatal risk factors. Methods. The study sample comprised 206 children with CP. Pertinent data were collected from medical records and included participants? gestational age at birth, medical history, and CP clinical characteristics. Risk factors were divided according to the timing of brain injury into prenatal, perinatal, and neonatal. Results. Hormonally maintained pregnancy (55.3%), twin pregnancy (28.9%), vaginal bleeding after the 20th week of gestation (21.1%), threatened abortion in the first half of pregnancy (13.2%), and maternal infection (10.5%) were identified as the main prenatal risk factors for CP. Prematurity (54.5%) was the leading perinatal risk factor, followed by low birthweight (50.8%), Apgar score < 7 (41.7%), assisted delivery (41.4%), and breech presentation (13.5%). Respiratory distress syndrome (16%), need for treatment in the Neonatal Intensive Care Unit (22.3%), assisted ventilation (18.4%), hypoxic-ischemic encephalopathy (11.2%), and neonatal convulsions (5.8%) were identified as the leading neonatal risk factors for CP. A statistically significant difference was found in the total number of perinatal risk factors in relation to gestational age (p < 0.001) and CP type (p = 0.006). Perinatal risk factors were most prevalent in preterm infants and children affected by the CP of spastic bilateral type. A statistically significant difference was noted in the distribution of CP types de-pending on the gestational age (p < 0.001). In particular, spastic bilateral CP type was most prevalent in the group of preterm-born children. Conclusion. CP is characterized by heterogeneous risk factors and is a result of interaction among multiple risk factors.
The Accounting Financial Expertise of the Audit Committee Chair and Oversight Effectiveness
Authors: Krishnamoorthy Ganesh , Bruynseels Liesbeth , De Groote Sander , Wright Arnold M. , Van Peteghem Mathijs
Published: April 2022

Prior research finds that the presence of accounting financial expertise (AFE) on the audit committee (AC) enhances financial reporting quality. The current study provides a broad examination of the effect of the AFE residing in the AC chair on the monitoring of financial reporting quality and the audit process. Based on a sample of over 13,840 observations from U.S. public companies, we find that AFE of the AC chair is associated with lower levels of earnings management and enhanced monitoring of the audit process. When augmented by AC members with AFE, AC chair AFE is also negatively associated with reduced misstatement risk. This finding suggests appointing an AFE to the AC may not in itself be sufficient to fully enhance oversight quality, unless the committee also has a chair who possesses AFE. Finally, chair AFE is also found to enhance the likelihood of reporting material control weaknesses and goodwill impairments.
A Machine Learning–Based Predictive Model to Identify Patients Who Failed to Attend a Follow-up Visit for Diabetes Care After Recommendations From a National Screening Program
Authors: Okada Akira , Hashimoto Yohei , Goto Tadahiro , Yamaguchi Satoko , Ono Sachiko , Ikeda Kurakawa Kayo , Nangaku Masaomi , Yamauchi Toshimasa , Yasunaga Hideo , Kadowaki Takashi
Published: April 2022

OBJECTIVE

Reportedly, two-thirds of the patients who were positive for diabetes during screening failed to attend a follow-up visit for diabetes care in Japan. We aimed to develop a machine-learning model for predicting people’s failure to attend a follow-up visit.

RESEARCH DESIGN AND METHODS

We conducted a retrospective cohort study of adults with newly screened diabetes at a national screening program using a large Japanese insurance claims database (JMDC, Tokyo, Japan). We defined failure to attend a follow-up visit for diabetes care as no physician consultation during the 6 months after the screening. The candidate predictors were patient demographics, comorbidities, and medication history. In the training set (randomly selected 80% of the sample), we developed two models (previously reported logistic regression model and Lasso regression model). In the test set (remaining 20%), prediction performance was examined.

RESULTS

We identified 10,645 patients, including 5,450 patients who failed to attend follow-up visits for diabetes care. The Lasso regression model using four predictors had a better discrimination ability than the previously reported logistic regression model using 13 predictors (C-statistic: 0.71 [95% CI 0.69–0.73] vs. 0.67 [0.65–0.69]; P < 0.001). The four selected predictors in the Lasso regression model were lower frequency of physician visits in the previous year, lower HbA1c levels, and negative history of antidyslipidemic or antihypertensive treatment.

CONCLUSIONS

The developed machine-learning model using four predictors had a good predictive ability to identify patients who failed to attend a follow-up visit for diabetes care after a screening program.
Experimental Study on Magnetorheological Damper Prototype and Obtaining Its Equivalent Damping Coefficients
Authors: ERGİN Turgay , ALTIPARMAK Duran
Published: April 2022

In this work, a magnetorheological (MR) damper prototype that provides controllable damping force was designed, manufactured and tested. The design and dimensions of the MR damper piston were determined according to the static magnetic analysis results made in ANSYS/Emag (Electromagnetics) software. The MR damper’s damping performance was tested in laboratory by utilizing a damper testing device. The tests were carried out under different currents applied to coil of the MR damper. According to the test results, the equivalent damping coefficients of the MR damper were calculated for different currents. The test results show that the highest damping force is 169.4 N with frequency of 3.18 Hz and applied current of 2 A. In this case, the equivalent damping coefficient is 302 Ns/m. The equivalent damping coefficient is 181 Ns/m when no current is supplied to the coil. The area of the dynamic force range also becomes larger with increasing the applied current. In addition, according to the quarter car model based simulation results in MATLAB/Simulink, it was seen that the semi-active suspension system using MR damper was more effective and successful in vibration mitigation.
The Effect of Suplementation of Sambiloto (Andrographis paniculata) Extract Through Drinking Water on Total Erythrocytes and Total Leucocytes of Broiler
Authors: Sirat Muhammad Mirandy Pratama , Hartono Madi , Santosa Purnama Edy , Ermawati Ratna , Fauzi Teo Achmad , Aini Nur , Arzakiyah Fina , Widodo Imam , Fauzan Teo Achmad
Published: April 2022

The aim of this study was to determine the effect and the best dose of Sambiloto (Andrographis paniculata) extract supplementation on total erythrocytes and total leukocytes in broilers. The study was conducted for 6 months, May – October 2021. Maintenance and treatment of broilers for 30 days was carried out at the Karang Anyar Farm broiler cage unit in Karang Anyar Village, Jati Agung District, South Lampung Regency, Lampung Province. The experimental study used a completely randomized design with five treatments. Each treatment consisted of 25 broilers of the Cobb CP 707 strain which were divided into 5 cages, so a total of 125 broilers in 25 cages. Sambiloto (Andrographis paniculata) as an immunomodulator was added to drinking water with different doses according to broiler body weight, namely drinking water without a liquid extract of Sambiloto (Andrographis paniculata) (P0); drinking water with Sambiloto liquid extract 0.05 cc/kg BW (3 mg/kg BW) (P1); 0.1 cc/kg BW (6 mg/kg BW) (P2); 0.2 cc/kg BW (12 mg/kg BW) (P3); 0.4 cc/kg BW (24 mg/kg BW) (P4). Total of 25 blood samples from 30-day-old broiler were taken through the brachial vein using a 3 mL syringe and stored in a 5 mL EDTA tube. Calculation of total erythrocytes and total leukocytes at the Palembang Health Laboratory and then the data were analyzed descriptively. The highest total erythrocyte in broilers was P0, the lowest was P4, the mean total erythrocyte was within normal limits for all treatments. The highest broiler leukocyte total was P2, the lowest was P3, the average total leukocyte for all treatments was above the normal range. The active compound in Sambiloto (Andrographis paniculata) is andrographolide which can act as an immunostimulant for specific and non-specific immune functions through NK cells, macrophages, and cytokine induction. The flavonoid content in sambiloto will also send intracellular signals to cell receptors to increase its activity when immune system activity is reduced which can increase the production of IL-2 thereby increasing lymphocyte proliferation, increasing the proliferation and differentiation of B and NK cells. The conclusion was that supplementation of Sambiloto (Andrographis paniculata) extract through drinking water can maintain the number of erythrocytes within normal limits and increase the number of leukocytes as an immune response after vaccination with the best supplementation dose in drinking water of 6 mg/kg BW which is equivalent to a volume of 0.1 cc/liquid extract. kg BB broiler.
Fingerprint Based Smart Home Automation and Security System
Authors: Al Rakib Md Abdullah , Rahman Md Moklesur , Uddin Salah , Alam Anik Md Shamsul , Talukder ABM Hasan , Samad Museum , Abbas Fysol Ibna
Published: April 2022

Wireless Controlled by Voice Automation in the Home Based on Bluetooth, a project that is moving forward with cell (application) in addition to giving the workspace to the elderly and injured, so they may control household utilities. Voice interest is based on their phone. The gadget is disguised in such a manner that it will be quick to pass on, present, figure out, run, and keep up with the dark person. Wires for house automation are also utilized to interconnect the many electrical equipment that are used in a home. This work may be run with a variety of options, such as a fingerprint sensor that will lock and unlock the door, or any other security system that will be installed in a home or business. And a leakage detector will track the system, and if it detects a leak, an automated SMS will be delivered to the user through GSM.
EKSISTENSI HIMPUNAN MAHASISWA JURUSAN SEBAGAI ORGANISASI INTERNAL DI FAKULTAS ILMU SOSIAL UNIMED
Authors: Simorangkir Lukas Partogi , Andayani Trisni
Published: April 2022

Penelitian ini bertujuan untuk mengetahui Eksistensi Himpunan Mahasiswa Jurusan di Fakultas Ilmu Sosial Unimed. Himpunan Mahasiswa Jurusan tersebut diangkat peneliti menjadi karya tulis karena peneliti merasa tertarik akan eksistensi yang dimiliki HMJ tersebut. Eksistensi HMJ sebagai organisasi di Fakultas Ilmu Sosial memang sangat popular di kalangan mahasiswa. Sehingga dalam penelitian ini penulis mengungkapkan bagaimana eksistensi HMJ tersebut. Jenis penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif. Adapun teknik pengumpulan data yang dilakukan adalah observasi dan wawancara secara mendalam. Teori yang digunakan dalam penelitian ini menggunakan teori organisasi Cyril soffer dan struktural fungsional. Informan dalam penelitian menggunakan 5 orang ketua dan dimisioner HMJ, 1 orang kepala bidang HMJ. Adapun hasil penelitian bahwasanya sebagai organisasi di fakultas HMJ pada awal dibentuknya sebagai wadah berdiskusi bagi mahasiswa. Jurusan membutuhkan sosok yang dapat menyalurkan berbagai informasi kepada mahasiswa dan mahasiswa kepada jurusan juga sebagai perencana program-program ekstrakulikuler. Bebrapa pelanggaran yang di dapatkan penulis dari informan merupakan pelanggaran yang sama perihal melaksanakan inagurasi yang dinilai merupakan tindakan kekerasan kepada mahasiswa baru, kegiatan tersebut sudah diilegalkan oleh universitas, tetapi tetap masi dilaksanakan oleh pihak terkait. Beberapa juga melakukan pelanggaran pribadi oleh mahasiswa untuk menjatuhkan nama baik jurusan di mata universitas.
Indahan Tukkus Jagar-jagar Pasae Robu dalam Adat Pernikahan Suku Batak Angkola di Kelurahan Tanobato Kecamatan Padangsidimpuan Utara Kota Padangsidimpuan
Authors: Siregar Mery Romaito , Malau Waston
Published: April 2022

Upacara pernikahan dalam adat suku Batak Angkola memiliki berbagai macam tradisi adat. Salah satu diantaranya, pemberian Indahan Tukkus Jagar-jagar Pasae Robu. Tradisi adat ini tidak lepas dari nilai-nilai sosial dan spiritual (perilaku), sehingga dalam pembuatan makanan adat ini harus melibatkan beberapa orang masyarakat, adapun yang menjadi arti penting dari makanan tersebut untuk mengarahkan kedua pengantin dalam menjalani hidup berumah tangga yang baik. Tujuan penelitin ini adalah untuk mengungkapkan secara jelas dapat melestarikan budaya lokal tersebut yang masih dipegang teguh oleh masyarakat suku Angkola. Penelitian ini menggunakan metode kualitatif dengan teknik observasi, wawancara, dan dokumentasi. Informan dari penelitian ini terdiri dari: harajaon, hatobangon, dalihan na tolu, dan ibu-ibu yang membuat indahan tukkus jagar-jagar pasae robu. Hasil dari penelitian bahwa masyarakat masih mengetahui cara pembuatan, penyajian, dan makna simbol yang terdapat dalam indahan tukkus jagar-jagar pasae robu. Apabila adat ini sudah terlaksana pada kedua pengantin maka selesailah adat orangtua terhadap anak gadisnya yang akan menikah. Diharapkan pada masyarakat dan generasi muda agar tetap melestarikan adat budaya lokal daerah sendiri dibandingan dengan budaya luar.
Defining the family as a legal category and a special phenomenon of social relations
Authors: Padun R.
Published: April 2022

The article compares different definitions of “family”, as the category of family is complex not only in terms of family law, but also in many sciences, such as philosophy, psychology, pedagogy, ethnography, demography, economics and sociology. Each branch of knowledge is of interest to the family in the “context” of their subject and methodology.In legal science, primarily in family law, this category is considered from the standpoint of its legal protection, primarily in connection with the protection of the rights and interests of individual family members. To properly understand the category of the family, it is necessary to define the functions of the family, which will ultimately determine the legal category of the family.It was found that no consensus was reached on the characteristics of the family. Among the features of the family - cohabitation, coexistence and residence, in addition to them - the existence of mutual rights and responsibilities, joint management, mutual moral and material support, etc., so the following legal definition of the family was proposed: “Seven is a legal relationship between persons based on marriage, kinship, adoption and other legal grounds, which is expressed in the fact that they are equally endowed with mutual personal non-property and property family, rights and responsibilities, common life, common interests and mutual legal responsibility “.                                                                                                                                                                     Taking into account the specifics of family rights guaranteed by Art. 8 of the Convention, the settlement of legal facts in the family law must take into account the limits of state influence on family relationships, as well as to maintain a balance in the regulation of general legal relations and private family relations of a personal nature, which in general should not be regulated by law or should be subject to minimal regulatory influence.Having a legal record of the term “family” will determine which social relations in the family should be protected by law, and which - to leave to regulate morals, customs, traditions, as family law should not regulate. all the relationships between people in the family, but only the most important among them.
The role of civil society in the formation of state ethno-national unity policy in Ukraine: legal principles
Authors: Motsa Andrii
Published: April 2022

The article analyzes the role, significance and influence of civil society on the formation of ethno-national unity policy in Ukraine. The prospects for solving the specified issues by improving national legislation in the field of state ethnopolitics are outlined.The specified topic analyzes the norms of the Constitution, the Laws of Ukraine «About National Minorities in Ukraine», «About Local Self-Government in Ukraine», «About Public Associations», the Electoral Code, as well as the Declaration of the Rights of Nationalities of Ukraine.Based on the analysis, in order to improve the legal base, which regulates relations in the field of national minorities, changes to the Constitution of Ukraine, developing of a new edition of the Law of Ukraine «About National Minorities in Ukraine» were proposed.Due to the lack of understanding of the concept of national-cultural autonomy, its place among other public institutions, the expediency of developing and adopting the laws of Ukraine «About national-cultural autonomy» and «About the Concept of State Ethnic Policy of Ukraine» was expained. It is determined that national-cultural autonomy has nothing to do with the administrative-territorial division of the state and the right to use representatives of national minorities, regardless of their accommodation, which is especially relevant for dispersed minorities. The proposed laws should correspond to the challenges of modern times, and in their basis a model of cooperation and partnership between civil society and the state must be placed.The necessity of developing and adopting the Law of Ukraine «About the procedure for attracting public associations to the process of formation and implementation of state policy in Ukraine», which will provide an opportunity to improve the mechanism of implementing the state responsibility before civil society, ensuring its systematic and consistent character was discovered.
Administrative mediation in the light of institutional transformations in Ukraine
Authors: Melenko O. , Stratiy O. , Hrindei L.
Published: April 2022

The article highlights the social significance of administrative mediation, which consists in the organization and development of civil society institutions (for example, public associations of mediators), including their public control over public administration as a system of bodies and organizations designed to implement goals and objectives given by the political (representative) power of the state. With the help of administrative mediation, society can legally «signal» to the representative authorities about certain problems in public relations (for example, on the basis of depersonalized statistical information and reports provided by associations of mediators), eliminate and find compromise in overcoming shortcomings of public administration together with the government and, finally, to move the process of modernization of the executive branch towards finding consensus at all levels of interaction between the state and society. The article proposes the author’s definition of «administrative mediation» as an extra- judicial legal form of voluntary settlement of an administrative dispute involving two or more parties, one of which is a subject of power, and a professional mediator arising from a violation of administrative law. The article presents a number of special features and characteristics of administrative mediation, which, unlike other types of mediation, require the application of specific institutions. For instance: inequality of the parties, the dispute is based on the public interest; the principles of confidentiality and voluntariness are relative; complex structure of the mediator’s financial reward; requires the involvement of independent experts; special requirements for the mediator. The article proposes the criteria according to which an administrative dispute can or cannot be resolved through the procedure of administrative mediation. The article proposes a number of legislative initiatives regarding the institutionalization and development of the institution of administrative mediation in Ukraine. Among them, it is proposed to introduce a special section in the Code of Administrative Procedure of Ukraine «Mediation» (as was done in Poland), where, among other things, clearly define the restrictive framework (criteria) for administrative disputes, according to which the procedure of administrative mediation can be applied.
Concepts and types of special administrative and legal status
Authors: Pushkareva N.
Published: April 2022

The article is devoted to the study of the concepts of “legal status”, “administrative and legal status” and “special administrative and legal status”. This article presents the author’s views on the content of the concepts of legal status, administrative and legal status and special administrative and legal status, considers the types of special administrative and legal status, subjects (carriers) of special administrative and legal, formulates the definition of “administrative guardianship”. examples of legislative acts containing legal norms regulating special administrative and legal status are given.

It is established that the general administrative-legal status is inherent in all persons, while the special administrative-legal status covers the circle of those people who are endowed with special rights and responsibilities in a certain sphere of public administration. These special rights and responsibilities arise on the basis of holding a certain position (for example, the administrative and legal status of a police officer, civil servant, serviceman) or in the case of a citizen’s will and special permit (firearms permit, hunting permit). Legal status requires the will of a state body to grant such a person or group of people such administrative and legal status. in territories with a special legal regime, it is acquired in the absence of the will of a person - a resident of the territory to obtain a special administrative and legal status. The presence of a special administrative and legal status can not only expand residents of territories with a special legal regime.
Preventive measures to ensure the sea fishing regime
Authors: Zagorodniuk S.
Published: April 2022

Marine areas that contain living resources are subject to international protection; their species, one of which is the maritime economic zone, have a special legal status: they can be marine - fishing and territorial areas of general

purpose. The legislation of Ukraine actualizes the problem of environmental protection, creation of conditions of inviolability of law enforcement activity of a set of norms of various branches of law.

The general causes and conditions of environmental crime are in the system of contradictions that arise from the interaction of man, society and nature. Their essence is that society, being part of the biosphere, resists the ecosystem due to limited opportunities for nature.

The growth of environmental crime is facilitated by the shortcomings of current legislation and its protection by relevant government agencies, the lack of mechanisms for its effective implementation.

Within the zones of general definition, the laws of Ukraine apply to all offenses. Such a zone is recognized as the territory of the respective state and the laws apply to persons who have committed the relevant offenses. In this case, there may be peculiarities in the application of laws that contain a blanket disposition. An example is environmental offenses, the responsibility for which is based on other regulations. In the conditions of such zones, the corresponding normative acts have specifics which distinguish their application in the territory of other states.

Within the exclusive (marine) economic zone, coastal states have the right to carry out exploration, development, management of natural resources, to exercise jurisdiction over the conservation of the marine environment, to conduct marine research
Transformation of the principle of freedom of contract in the process of historical development
Authors: Rasʹko Yu.
Published: April 2022

The article examines the formation of freedom of contract in the process of historical development of civil law regulation of social relations. The understanding of the essence of freedom and freedom of contract in Roman law, periods of medieval and bourgeois law, as well as in the modern period is analyzed. The purpose of restricting the freedom of contract has been studied.

It has been established that in the 19th century freedom of contract became a universal principle of maintaining free competition, and in the 20th century there were processes of restricting contractual freedom, which was due to the following factors: increasing number of standard contracts, state intervention in contractual relations and consumer protection.

It was found that despite the lack of legislative enshrinement of the principle of freedom of contract in the civil codes of the Soviet period, elements of dispositiveness and contractual freedom were present in civil law, which was completely natural due to the legal nature of the contract based on freedom and expression.

It is substantiated that freedom of contract is both a principle and an element of the essential system of "human freedom". Freedom determines the state and capabilities of man in society, is also a fundamental value, the basis for determining the boundaries of legal regulation of civil relations. It is established that at the beginning of the XIX century freedom of contract became a legally defined universal principle of maintaining free competition and the basis of private law relations, and since the end of this century it is limited by law.

Freedom of contract also allows concluding a contract that is not provided by the norms of the Central Committee of Ukraine. The position of scholars is supported that a contract that is not provided by law is a contract that is not defined by type or type. For such contracts, it is recommended to first apply the rules that define a similar type of contract (analogy of law), and in the absence - general civil law.