bluuebunny/crossref_metadata_2025 huggingface dataset:
Surgical Outcomes and Prognostic Factors of G3 Pancreatic Neuroendocrine Carcinomas: A Consecutive Analysis Based on Previous Study Results
Authors: Luo Xinmei , Yang Min , Tian Bole , Liu Xubao , Duan Kaiti , Zhang Yi
Published: June 2022

In 2017, the World Health Organization (WHO) officially defined pancreatic neuroendocrine neoplasms into well-differentiated tumors, namely G1/G2/G3 pancreatic neuroendocrine tumors, and poorly differentiated carcinomas referring to G3 pancreatic neuroendocrine carcinomas (p-NECs). However, the surgical outcomes and prognostic factors of G3 p-NECs are still unclear. Methods: We retrospectively collected and analyzed the data of eligible patients with G3 p-NECs defined by the WHO 2017 grading classification. Results: We eventually identified 120 patients with G3 p-NECs, including 72 females and 48 males, with a median age of 53 y. The 3-year overall survival (OS) of G3 p-NECs by Kaplan–Meier method was 37.3%. The 3-year OS for functional G3 p-NECs was 57.4%, which was statistically longer than 23.0% of non-functional ones (p = 0.002). Patients with surgical resection presented a significantly better 3-year OS than those with palliative operation (43.3% vs. 13.1%; p < 0.001). The 3-year OS for Stage Ⅰ, Stage Ⅱ, Stage Ⅲ, and Stage Ⅳ was 87.1%, 56.5%, 12.9%, and not applicable, respectively (p < 0.001). We demonstrated in a Cox regression model that palliative operation (p = 0.013), vascular infiltration (p = 0.039), lymph node involvement (p = 0.024), and distant metastasis (p = 0.016) were independent predictors of poor outcome for patients with surgically treated G3 p-NECs. Conclusion: Our data in the present analysis indicated that patients with G3 p-NECs could significantly benefit from surgical resection. Meanwhile, vascular infiltration, lymph node involvement, and distant metastasis were independent predictors of poor outcome for these patients.
Visual Outcomes of Pupilloplasty in Ocular Trauma and Iatrogenic Damage
Authors: Nowomiejska Katarzyna , Haszcz Dariusz , Adamczyk Katarzyna , Brzozowska Agnieszka , Bonfiglio Vincenza , Toro Mario Damiano , Rejdak Robert
Published: June 2022

Purpose: To report the visual outcomes of different techniques for iris pupilloplasty in eyes after traumatic and iatrogenic damage. Methods: 70 consecutive eyes with posttraumatic (80%) and postoperative (20%) iris damage were included. According to the preoperative diagnosis, the eyes were divided into three groups: mydriasis (50%), partial iris defects (24%), and iridodialysis (26%). Multiple techniques were performed: the Siepser slip-knot technique, the “lasso” technique, and suturing to the sclera. These techniques were combined in some cases. Results: The best improvement of visual acuity was found for the Siepser slip-knot technique with a median of 0.7 (SD ± 0.83) before surgery and 0.52 logMAR (SD ± 0.65) after surgery with regard to the surgical technique, and for mydriasis with a median of 0.7 (SD ± 0.75) before surgery and 0.52 logMAR (SD ± 0.49) after surgery with regard to preoperative diagnosis. Pupilloplasty was combined with additional surgery (corneal suturing, secondary intraocular lens implantation, anterior or pars plana vitrectomy) in 80% of cases. Apart from corneal suturing, all additional procedures ensured improvement in visual acuity. Conclusions: The slip-knot technique was the only suturing technique that resulted in a significant improvement in visual acuity. Other surgical procedures are usually needed in the majority of cases that undergo pupilloplasty, and they also give visual gain.
Home-Based Adaptation to Night-Time Non-Invasive Ventilation in Patients with Amyotrophic Lateral Sclerosis: A Randomized Controlled Trial
Authors: Volpato Eleonora , Vitacca Michele , Ptacinsky Luciana , Lax Agata , D’Ascenzo Salvatore , Bertella Enrica , Paneroni Mara , Grilli Silvia , Banfi Paolo
Published: June 2022

Background: Initiation to Non-Invasive Ventilation (NIV) in amyotrophic lateral sclerosis (ALS) can be implemented in an inpatient or outpatient setting. Aims: We aimed to evaluate the efficacy of adaptation (the number of needed sessions) to home-based NIV compared to an outpatient one in ALS in terms of arterial carbon dioxide (PaCO2) improvement. NIV acceptance (mean use of ≥5 h NIV per night for three consecutive nights during the adaptation trial), adherence (night-time NIV usage for ≥150 h/month), quality of life (QoL), and caregiver burden were secondary outcomes. Methods: A total of 66 ALS patients with indications for NIV were involved in this randomized controlled trial (RCT): 34 underwent NIV initiation at home (home adaptation, HA) and 32 at multiple outpatient visits (outpatient adaptation, OA). Respiratory function tests were performed at baseline (the time of starting the NIV, T0) together with blood gas analysis, which was repeated at the end of adaptation (T1) and 2 (T2) and 6 (T3) months after T1. NIV adherence was measured at T2 and T3. Overnight cardiorespiratory polygraphy, Short Form Health Survey (SF-36), Caregiver Burden Inventory (CBI), Caregiver Burden Scale (CBS), and Zarit Burden Interview (ZBI) were performed at T0, T2, and T3. Results: Fifty-eight participants completed the study. No differences were found between groups in PaCO2 at T1 (p = 0.46), T2 (p = 0.50), and T3 (p = 0.34) in acceptance (p = 0.55) and adherence to NIV at T2 and T3 (p = 0.60 and p = 0.75, respectively). At T2, the patients’ QoL, assessed with SF-36, was significantly better in HA than in OA (p = 0.01), but this improvement was not maintained until T3 (p = 0.17). Conclusions: In ALS, adaptation to NIV in the patient’s home is as effective as that performed in an outpatient setting regarding PaCO2, acceptance, and adherence, which emphasizes the need for further studies to understand the role of the environment concerning NIV adherence.
Endothelial Dysfunction and Arterial Stiffness in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Authors: Wu Hao , Xu Meihua , Hao Hong , Hill Michael A. , Xu Canxia , Liu Zhenguo
Published: June 2022

Population-based studies have suggested that patients with inflammatory bowel disease (IBD) might be at an increased risk for cardiovascular diseases. A meta-analysis was performed on clinical studies to evaluate endothelial function, arterial stiffness, and carotid intima-media thickness (cIMT) in patients with IBD, after searching PubMed, Embase, Cochrane library, and Web of Science databases. A random-effects model was used to allow for the pooling of studies and for determination of the overall effect. After exclusion, a total of 41 eligible studies with 2330 patients with IBD and 2032 matched controls were identified and included for the analysis. It was found that cIMT was significantly increased in patients with IBD as compared with that in matched controls (Cohen’s d: 0.63; 95% CI: 0.34, 0.93; I2 = 91.84%). The carotid–femoral pulse wave velocity was significantly higher in patients with IBD compared to that in matched controls (Cohen’s d: 0.76; 95% CI: 0.54, 0.98; I2 = 70.03%). The augmentation index was also significantly increased in patients with IBD compared to matched control subjects (Cohen’s d: 0.35; 95% CI: 0.08, 0.63; I2 = 61.37%). Brachial artery flow-mediated dilatation was significantly decreased in patients with IBD than that in matched controls (Cohen’s d: −0.73; 95% CI: −1.10, −0.36; I2 = 81.02%). Based on the meta-analysis, it was found that patients with IBD exhibit significant endothelial dysfunction, increased arterial stiffness, and cIMT. Thus, patients with IBD may benefit from aggressive risk stratification for cardiovascular diseases.
Effects of Electromyographic Biofeedback on Functional Recovery of Patients Two Months after Total Knee Arthroplasty: A Randomized Controlled Trial
Authors: Sklempe Kokic Iva , Vuksanic Matko , Kokic Tomislav , Peric Ivan , Duvnjak Ivana
Published: June 2022

The incidence of total knee arthroplasty (TKA) is steadily increasing worldwide. Therefore, it is crucial to develop efficient rehabilitation protocols and investigate the innovations in medical technology, which could improve rehabilitation outcomes. The aim of the study was to investigate the effect of adding electromyographic biofeedback (EMG-BF) to the conventional program of rehabilitation after TKA on quality of life, intensity of pain, and functional performance. The study was designed as a randomized controlled trial. A total of 131 patients were randomly assigned to two groups: an experimental group (n = 67; median age 70 (IQR 10)), and a control group (n = 64; median age 69 (IQR 9)). Both groups participated in an inpatient program of 21 days of rehabilitation, including land-based and aquatic exercise therapy, electrotherapy, and education. In the experimental group, a portion of land-based exercise therapy was supplemented by EMG-BF. A numeric rating scale (NRS), Knee Injury and Osteoarthritis Outcome Score (KOOS), use of mobility aids, 30 s chair stand test (CST), and timed up and go (TUG) test were used to measure outcomes. Both groups improved their functional abilities from day 1 to day 21 of rehabilitation. A higher proportion of participants did not use a walking aid (p < 0.002), and their NRS, KOOS, 30 s CST and TUG scores improved (p < 0.001). There were no significant differences between the groups in the outcomes. EMG-BF did not provide additional benefits to the conventional rehabilitation after TKA.
Effect of Subgingival Instrumentation on Neutrophil Elastase and C-Reactive Protein in Grade B and C Periodontitis: Exploratory Analysis of a Prospective Cohort Study
Authors: Eickholz Peter , Asendorf Anne , Schröder Mario , Schacher Beate , Oremek Gerhard M. , Schubert Ralf , Wohlfeil Martin , Zuhr Otto
Published: June 2022

Background: Assessment of the effect of subgingival instrumentation (SI) on systemic inflammation in periodontitis grades B (BP) and C (CP). Methods: In this prospective cohort study, eight BP and 46 CP patients received SI. Data were collected prior to and 12 weeks after SI. Blood was sampled prior to, one day, 6, and 12 weeks after SI. Neutrophil elastase (NE), C-reactive protein (CRP), leukocyte count, lipopolysaccharide binding protein, interleukin 6 (IL-6) and IL-8 were assessed. Results: Both groups showed significant clinical improvement. NE was lower in BP than CP at baseline and 1 day after SI, while CRP was lower in BP than CP at baseline (p < 0.05). NE and CRP had a peak 1 day after SI (p < 0.05). Between-subjects effects due to CP (p = 0.042) and PISA (p = 0.005) occurred. Within-subjects NE change was confirmed and modulated by grade (p = 0.017), smoking (p = 0.029), number of teeth (p = 0.033), and PISA (p = 0.002). For CRP between-subjects effects due to BMI (p = 0.008) were seen. Within-subjects PISA modulated the change of CRP over time (p = 0.017). Conclusions: In untreated CP, NE and CRP were higher than in BP. SI results in better PPD and PISA reduction in BP than CP. Trial registration: Deutsches Register Klinischer Studien DRKS00026952 28 October 2021 registered retrospectively.
Knowledge Spillover through Blockchain Network in Tourism: Development and Validation of Tblock Questionnaire
Authors: Avdimiotis Spyros , Moschotoglou Panagiotis
Published: June 2022

With the advent of disruptive technologies, blockchain is considered to be the most prominent technology that has the potential to have a significant influence on the knowledge management field, particularly knowledge sharing, knowledge transfer and knowledge spillover. This paper outlines the development and validation of the Knowledge Spillover through Tourism Blockchain Questionnaire, the TBlockQ. The purpose of this questionnaire is to acknowledge the key factors aligned with the level of knowledge spillover generated within a blockchain network. The TBlockQ was a synthesis of 29 5-point Likert scaled questions. A total of 422 correspondents participated in this study. The results of this study outline the reliability and validation of this questionnaire. The reliability statistics of all the items are high. Three factors, revealed from the factor analysis, identifying the knowledge spillover from a blockchain network in the tourism industry were: (a) networking expansion, improvement and spillover intention, (b) entrepreneurial and future prospects and (c) trust and security.
Unearthing the Alleviatory Mechanisms of Brassinolide in Cold Stress in Rice
Authors: Xu Qingshan , Wei Qianqian , Kong Yali , Zhu Lianfeng , Tian Wenhao , Huang Jing , Pan Lin , Jin Qianyu , Zhang Junhua , Zhu Chunquan
Published: June 2022

Cold stress inhibits rice germination and seedling growth. Brassinolide (BR) plays key roles in plant growth, development, and stress responses. In this study, we explored the underlying mechanisms whereby BR helps alleviate cold stress in rice seedlings. BR application to the growth medium significantly increased seed germination and seedling growth of the early rice cultivar “Zhongzao 39” after three days of cold treatment. Specifically, BR significantly increased soluble protein and soluble sugar contents after three days of cold treatment. Moreover, BR stimulated the activity of superoxide dismutase, catalase, peroxidase, and ascorbate peroxidase; thereby alleviating cold-induced damage and increasing glutathione content and the GSH/GSSG ratio while concomitantly reducing H2O2 content. BR upregulated the expression levels of cold-response-related genes, including OsICE1, OsFer1, OsCOLD1, OsLti6a, OsSODB, OsMyb, and OsTERF2, and downregulated that of OsWRKY45, overall alleviating cold stress symptoms. Thus, BR not only upregulated cellular osmotic content and the antioxidant enzyme system to maintain the physiological balance of reactive oxygen species under cold but, additionally, it regulated the expression of cold-response-related genes to alleviate cold stress symptoms. These results provide a theoretical basis for rice breeding for cold resistance using young seedlings.
Microstructure Formation and Carbon Partitioning with Austenite Decomposition during Isothermal Heating Process in Fe-Si-Mn-C Steel Monitored by In Situ Time-of-Flight Neutron Diffraction
Authors: Onuki Yusuke , Umemura Kazuki , Fujiwara Kazuki , Tanaka Yasuaki , Tomida Toshiro , Kawano Kaori , Sato Shigeo
Published: June 2022

Retained austenite is a key feature used to realize the transformation-induced plasticity in bainitic high strength steels. In this study, the authors focused on the formation of metastable austenite in Fe-0.61C-1.9Si-0.98Mn (mass%) during isothermal heating processes using in situ neutron diffraction techniques. Quantitative discussion of carbon partitioning processes is enabled by applying an in situ phase fraction analysis considering crystallographic textures, in addition to the carbon concentration estimation based on the lattice parameter of austenite. The carbon partitioning behavior is inhomogeneous, resulting in a bimodal carbon concentration distribution in austenite. The carbon enriched, high carbon austenite is stable during isothermal heating at 673 K and is retained even after cooling to room temperature. The remainder is low carbon austenite, which is gradually consumed by bainite transformation. Above 723 K, the high carbon austenite also decomposes to ferrite and cementite due to the fast diffusion of Si. Conversely, below 623 K, cementite is stabilized even without the diffusion of Si. These cementite formation mechanisms prevent the formation and retention of high carbon austenite. The inhomogeneous carbon distribution and cementite formation must be carefully considered to precisely predict the microstructure formation in Si-added bainitic steels.
Scan-Centric, Frequency-Based Method for Characterizing Peaks from Direct Injection Fourier Transform Mass Spectrometry Experiments
Authors: Flight Robert M. , Mitchell Joshua M. , Moseley Hunter N. B.
Published: June 2022

We present a novel, scan-centric method for characterizing peaks from direct injection multi-scan Fourier transform mass spectra of complex samples that utilizes frequency values derived directly from the spacing of raw m/z points in spectral scans. Our peak characterization method utilizes intensity-independent noise removal and normalization of scan-level data to provide a much better fit of relative intensity to natural abundance probabilities for low abundance isotopologues that are not present in all of the acquired scans. Moreover, our method calculates both peak- and scan-specific statistics incorporated within a series of quality control steps that are designed to robustly derive peak centers, intensities, and intensity ratios with their scan-level variances. These cross-scan characterized peaks are suitable for use in our previously published peak assignment methodology, Small Molecule Isotope Resolved Formula Enumeration (SMIRFE).
Treatment Reducing Endothelial Activation Protects against Experimental Cerebral Malaria
Authors: Mota Sabrina , Bensalel Johanna , Park Do Hee , Gonzalez Sandra , Rodriguez Ana , Gallego-Delgado Julio
Published: June 2022

Cerebral malaria (CM) is the most severe neurological complication of malaria caused by Plasmodium falciparum infection. The available antimalarial drugs are effective at clearing the parasite, but the mortality rate remains as high as 20% of CM cases. At the vascular level, CM is characterized by endothelial activation and dysfunction. Several biomarkers of endothelial activation have been associated with CM severity and mortality, making the brain vascular endothelium a potential target for adjunctive therapies. Statins and Angiotensin II Receptor Blockers (ARBs) are drugs used to treat hypercholesterolemia and hypertension, respectively, that have shown endothelial protective activity in other diseases. Here, we used a combination of a statin (atorvastatin) and an ARB (irbesartan) as adjunctive therapy to conventional antimalarial drugs in a mouse experimental model of CM. We observed that administration of atorvastatin–irbesartan combination decreased the levels of biomarkers of endothelial activation, such as the von Willebrand factor and angiopoietin-1. After mice developed neurological signs of CM, treatment with the combination plus conventional antimalarial drugs increased survival rates of animals 3–4 times compared to treatment with antimalarial drugs alone, with animals presenting lower numbers and smaller hemorrhages in the brain. Taken together, our results support the hypothesis that inhibiting endothelial activation would greatly reduce the CM-associated pathology and mortality.
Introducing Three-Dimensional Scanning for Phenotyping of Olive Fruits Based on an Extensive Germplasm Survey
Authors: Manolikaki Ioanna , Sergentani Chrysi , Tul Safiye , Koubouris Georgios
Published: June 2022

Morphological characterization of olive (Olea europaea L.) varieties to detect desirable traits has been based on the training of expert panels and implementation of laborious multiyear measurements with limitations in accuracy and throughput of measurements. The present study compares two- and three-dimensional imaging systems for phenotyping a large dataset of 50 olive varieties maintained in the National Germplasm Depository of Greece, employing this technology for the first time in olive fruit and endocarps. The olive varieties employed for the present study exhibited high phenotypic variation, particularly for the endocarp shadow area, which ranged from 0.17–3.34 cm2 as evaluated via 2D and 0.32–2.59 cm2 as determined by 3D scanning. We found significant positive correlations (p < 0.001) between the two methods for eight quantitative morphological traits using the Pearson correlation coefficient. The highest correlation between the two methods was detected for the endocarp length (r = 1) and width (r = 1) followed by the fruit length (r = 0.9865), mucro length (r = 0.9631), fruit shadow area (r = 0.9573), fruit width (r = 0.9480), nipple length (r = 0.9441), and endocarp area (r = 0.9184). The present study unraveled novel morphological indicators of olive fruits and endocarps such as volume, total area, up- and down-skin area, and center of gravity using 3D scanning. The highest volume and area regarding both endocarp and fruit were observed for ‘Gaidourelia’. This methodology could be integrated into existing olive breeding programs, especially when the speed of scanning increases. Another potential future application could be assessing olive fruit quality on the trees or in the processing facilities.
Fluid Production Dataset for the Assessment of the Anthropogenic Subsidence in the Po Plain Area (Northern Italy)
Authors: Eid Celine , Benetatos Christoforos , Rocca Vera
Published: June 2022

Fluid produced/injected volumes from/into underground natural formations and their spatial allocation play a key role in addressing the superposition of anthropogenic subsidence effects, but the definition of coherent datasets is usually very challenging. In this paper, the creation of a gas and water production dataset for the Po Plain area in northern Italy is presented, focusing on the Emilia-Romagna region (an industrialized, highly-populated area characterized by rapid subsidence). The produced volumes and their spatial/temporal allocation are gathered from different sources, analyzed, and organized via dedicated georeferenced maps. The geological framework of the Po Plain is delineated, with attention to the superficial aquifers. Reference ranges of petrophysical and pseudo-elastic parameters are reported for both aquifer and reservoir formations. Water extractions from the superficial unconsolidated sediments are widespread, both in space and time; instead, primary gas production and underground storage of natural gas, involving deeper formations, are spatially and temporally well constrained. Drastic increases in water production and high concentrations of gas production temporally coincided between the 1950s and 1970s. The ‘hotspots’ of the strongest superposition are recognized in Piacenza, Ferrara, Bologna, and Ravenna provinces. Qualitative and quantitative information represent a reference source for both Oil and Gas Societies and Regional/National authorities in addressing the subsidence analysis to plan the field production life and predict the environmental consequences.
How Generic Is Eternal Inflation?
Authors: Greenwood Ross , Aguirre Anthony
Published: June 2022

Everlasting inflation has far-reaching implications for cosmology and the standing of self-localizing inferences made by observers, which have been subjects of renewed interest in light of the growing acceptance of theory landscapes and the attendant anthropic arguments. Under what assumptions and to what extent does inflation generically produce an eternal “multiverse,” without fine-tuning with respect to measures over the space of inflationary cosmologies driven by a single minimally coupled scalar field? We address this and related questions with numerical simulations of inflationary dynamics across populations of randomly generated inflation models, instantiating a few particular simply-defined measures.
The Effects of Investment in Major Construction Projects on Regional Economic Growth Quality: A Difference-In-Differences Analysis Based on PPP Policy
Authors: Wang Fang , Yao Ming , Huang Xianhua , Guo Hao , Zheng Penghui , Yu Hongwei
Published: June 2022

The investment in Major Construction Projects (MCPs) has a counter-cyclical impact on quantitative GDP increases during the recession period. However, its impact on the quality of economic growth is still unknown. Based on the data of prefecture-level cities in China from 2008 to 2017, we construct an economic Quality Growth Index (QGI) including sustainable development factors and take the PPP (Public–Private Partnership projects) policy as a quasi-natural experiment to design a Difference-In-Differences (DID) strategy for the first time to estimate the effects of the MCPs investment on the sustainable development of regional economies. We find that the MCPs investment can significantly improve the quality of regional economic growth. The MCPs investment can improve the quality of regional economic growth by enhancing innovation and entrepreneurship at the regional levels. Our findings may provide empirical evidence to support the policy of increasing investment into infrastructure constructions to promote sustainable development in the current economic recession under the COVID-19 pandemic.
A Systematic Literature Review of the Contribution Accumulation Makes to Psychological and Physical Trauma Sustained through Childhood Maltreatment
Authors: Bryce India , Collier Simone
Published: June 2022

The pervasive effects of cumulative harm resulting from adverse childhood experiences influence all aspects of an individual’s life course. Research highlights a relationship between accumulation and trauma symptomology across all domains of harm and risk. A systematic literature review was conducted to explore and synthesize the current evidence base for the contribution accumulation makes to psychological and physical injury of childhood trauma. A search was conducted relevant to two areas of interest: (a) “cumulative harm” or “cumulative trauma” and (b) “consequences and outcomes”. Database searches and further manual searches yielded a total of 1199 articles, and 12 studies satisfied all the inclusion criteria. Only studies that were peer-reviewed and published between January 2011 and January 2022 were included. The evidence from the review indicated that multiplicity and polyvictimization, parental history and intergenerational transmission of trauma, systemic cumulative harm, and developmental lifespan outcomes were associated with the likelihood and impact of the accumulation of physical and psychological injury. The findings of this review contribute valuable knowledge to allow for a better understanding of the physical and psychological impact of accumulated and chronic childhood trauma. This knowledge will improve intervention, prevention, and management strategies for helping professionals working with traumatized or vulnerable children and adults.
Multifactorial Analysis to Determine the Applicability of Wind Power Technologies in Favorable Areas of the Colombian Territory
Authors: Rodriguez-Caviedes Andrés , Gil-García Isabel C.
Published: June 2022

Colombia has an energy matrix that is mostly hydroelectric and includes renewable energies such as wind power, which represents a minor contribution. The only operational wind farm is in the northern part of the country, where more projects will be implemented in the future in search of increasing the installed capacity and electricity generation. However, the wind potential and behavior of other areas of the national territory have been little reviewed. The most recommended method to characterize the potential in different areas of Colombia is to use real data, generating vertical extrapolations and respecting the good practices of the wind industry. The foregoing not only allows the generation of statistical and descriptive characterizations but also, together with the climatological, geographical, and technological variables (turbines), an estimate of the generable energy that can be obtained. In the described study, we applied specialized software to generate a rating matrix, from which it was possible to issue an opinion on five possible locations obtained from the theoretical development of micrositing, where 14 factors were reviewed. There is no published research of this nature for the country, so it is relevant in terms of novelty. Finally, it can be concluded that in Colombia, the wind potential should not be associated with a specific region, since there are data throughout the territory where this type of research can be replicated.
Pass-by noise prediction of motor vehicles using gradient boosted models and physical calculations of longitudinal driving dynamics
Authors: Knappe F. , Rosskopf J.
Published: June 2022

In the prior decades, automotive manufacturers have steadily improved the vibroacoustics performance of their products. This process is highly influenced by the continuously rising requirements on regulations of noise emissions of motor vehicles, also known as pass-by noise. The legal
requirements, demanding the reduction of the exterior noise emissions of motor vehicles, are caused by the impact of noise on human health. The latest legal norm of the Economic Commission for Europe (ECE) is the ECE R51.03 test, including continuous reductions of the allowed pass-by noise
sound pressure level of motor vehicles. Additionally, the need for faster development cycles results in more intensive use of digital models to predict the expected physical behavior of future products. These models extend the so-called digital twin, which has gained a high importance in automotive
manufacturing. Acoustic state-of-the-art simulation and analysis methods fail at the complexity of the over-all pass-by noise, consisting of multiple partial sound sources. These multiple sources are partly correlated, resulting in the absence of trivial deconvolution methods. This paper presents
a digital representation of motor vehicles regarding their noise emissions by using machine learning techniques combined with physical calculations of longitudinal driving dynamics. Gradient boosted models are used to predict the exterior sound pressure levels of motor vehicles. The developed
algorithm permits the possibility to predict the expected pass-by noise of future cars in early stages of the digital development process. This allows original equipment manufacturers to detect necessary changes to concepts and construction models of future cars. The prediction results are
validated for three engines.
Acoustic performance of cavities with gradient changes of cavity numbers under low lattice constant in a soft elastic medium
Authors: Wang Shibo , Hu Bo , Li Song , Zhang Lanyue , Shi Jie
Published: June 2022

Air cavities with particular arrangements embedded in elastic layers are generally used as anechoic coatings. In this paper, an idea of cavity numbers with gradient changes is introduced in a soft elastic medium that comprises periodical cylindrical cavities to enhance the low-frequency
absorption capacity effectively. The presented model provides a sound absorption coefficient that is higher than 0.5 in the frequency ranges of 75 to 95 Hz and 380 to 720 Hz. Thus, validating the idea can effectively enhance the low-frequency absorption capacity compared with those in previous
literature. Analytical results based on effective medium approximation theory are compared with those obtained numerically using the finite element method. These results indicate that the invalidity of the analytical model is due to the coupling between cavities under low lattice constant.
Power density dissipation and displacement vectors are plotted to study sound absorption mechanism, thereby showing that the dissipated energy is mainly resulted from the multiple-scattering effect. The scattering between cavities induces the transverse wave caused by the wave mode conversion
dissipates in the elastic medium and results in sound absorption. Simulation results show that the absorption peaks can be effectively manipulated by tuning the gradient profile of the cavity numbers. The proposed model is then verified by the corresponding experiment. Results obtained numerically
and experimentally are agreed well, and its feasibility is verified. The presented model would offer a new approach for the metamaterial design on low-frequency broadband sound absorption and could have potential applications on the design of anechoic coatings.
PERANCANGAN SISTEM INFORMASI PUBLIKASI DIGITAL PADA USAHA KULINER BERMODAL SEDERHANA
Authors: Raharjo Riyanto Dwi , Hasugian Leonardi Paris
Published: June 2022

Dalam industri kuliner terdapat dua kategori usaha yakni bermodal besar, dan bermodal sederhana. Kedua kategori ini memiliki perbedaan yang cukup signifikan. Sering kali terlihat banyak dari usaha kuliner yang tidak bertahan lama dalam operasinya, terutama kuliner sederhana. Salah satu penyebab dari masalah ini adalah minimnya publikasi pada kuliner sederhana. Jangkauan informasi kuliner sederhana juga tidak begitu luas. Banyak platform kuliner digital seperti Zomato atau Foodsesive. Dengan platform seperti zomato kuliner besar dapat melakukan publikasi dengan lebih efektif yang akan berdampak pada jangkauan dan jumlah pelanggan. Banyak usaha kuliner sederhana yang gagal berkembang akibat kurangnya pelanggan. Penyebab utamanya adalah informasi kuliner sederhana tidak tersebar luas. Penelitian ini bermaksud untuk membangun sistem informasi publikasi digital khusus untuk kuliner sederhana. Sistem akan menyediakan lahan bagi pelanggan dan pemilik usaha untuk berbagi informasi. Dimulai dari alamat, harga, hidangan, hingga penilaian pelanggan. Metode deskriptif digunakan dalam penyusunan penelitian, guna menghasilkan penelitian mendetail terhadap lingkungan usaha, objek penelitian, serta kerangka sistem yang berjalan pada objek penelitian. Hasil pembangunan sistem informasi publikasi ini adalah sebagai sistem informasi publikasi digital bagi kuliner sederhana yang membutuhkan tempat menyebarkan informasi dan memasarkan usahanya dengan lebih baik.
SISTEM REGISTRASI SURAT PERINTAH TUGAS (SPT) DI DINAS PEKERJAAN UMUM, PENATAAN RUANG DAN PERTANAHAN PROVINSI KEPULAUAN RIAU
Authors: Adiwijaya Fakhrian Fadlia , Amaruloh Dikri Salik , Mulya Andre Riana
Published: June 2022

Dinas PUPR merpakan salah satu dinas yang ada di bawah pemerintahan kota Tanjungpinang Provinsi kepulauan riau, lingkup pekerjaannya meliputi bidang pekerjaan umum dan tata ruang di pemerintahaan kota Tanjungpinang. Dalam melaksanakan tugasnya diperlukan surat perintah tugas (SPT) yang diserahkan ke bidang sekretariat. Pencatatan SPT yang dilakukan saat ini memiliki kekurangan saat akan melakukan pencarian data yang sudah dicatat, dan pembuatan laporan SPT setiap bulannya, sehingga diperlukan aplikasi untuk membantu registrasi SPT di dinas PUPR tersebut. Aplikasi yang akan dibangun akan menggunakan teknologi website dengan Bahasa pemrograman PHP dan database MySQL. Berdasarkan hasil pengujian, aplikasi yang dibangun dapat membantu pelaksanaan registrasi SPT dari mulai penyimpanan, pencarian data, serta pembuatan laporan bulanan di dinas PUPR.
SUPPORT VECTOR MACHINE UNTUK EKSTRAKSI DOKUMEN KARYA ILMIAH
Authors: Jihad Jihad , Widiastuti Nelly Indriani , Dewi Kania Evita
Published: June 2022

Ekstraksi informasi dokumen karya tulis ilmiah proses ekstraksi karya ilmiah secara otomatis untuk mendapatkan informasi terstruktur. Penelitian bertujuan untuk mengukur performansi Support Vector Machine (SVM) dalam mengektrak informasi didalam karya ilmiah. Dokumen karya ilmiah yang digunakan dalam penelitian ini adalah berupa lembar sampul dan abstrak dari skripsi, yang tersimpan dalam bentuk format .pdf. Setiap dokumen diubah terlebih dahulu ke format text. Hasil mengubah format dokumen masuk ke dalam tahapan persiapan, yaitu filtering, segmentasi, tokenizing, pelabelan, ektraksi fitur, dan seleksi fitur. Fitur yang digunakan dalam penelitian ini ada sebanyak 14 fitur. Hasil dari seleksi fitur setiap dokumen masuk kedalam proses klasifikasi untuk menentukan mengklasifikasi 16 kelas dari setiap dokumen tersebut. Di dalam penelitian ini performansi dari model yang dibuat oleh SVM mengunakan akurasi. Berdasarkan pengujian yang telah dilakukan dengan nilai gamma=0.5, dihasilkan akurasi tanpa Information Gain sebesar 90.68% sementara akurasi dengan Information Gain sebesar 90.99%. Untuk nilai error rate sebesar 9.32%, nilai precision sebesar 93.79%, nilai recall sebesar 90.74% dan nilai f-1 score sebesar 89.21%. Kesalahan yang paling banyak terjadi, pada pengklasifikasian judul lembar sampul. Kesalahan ini terjadi dikarenakan didalam penelitian ini dokumen yang digunakan, lembar sampul dan abstrak karya ilmiah, berasal dari sebuah dokumen yang sama, sehingga judul lembar sampul dan abstrak berisi hal yang sama, sehingga judul lembar sampul sering terklasifikasi judul abstrak.
PENGARUH KETERLIBATAN SUAMI DAPAT MENURUNKAN KECEMASAN IBU HAMIL DENGAN MALARIA
Authors: Runtuwene Linda , Ahmad Mardiana , Syamsuddin Saidah , Massi Nasrum , Arifuddin Sharvianty , Usman Andi Nilawati
Published: June 2022

Stres pada ibu hamil adalah risiko komplikasi, yang dapat membahayakan janin. Kontribusi risiko komplikasi tersebut salah satunya adalah kehamilan dengan malaria. Keterlibatan suami memberikan efek positif pada kesiapan persalinan ibu hamil. Penelitian ini bertujuan untuk mengetahui keterlibatan suami terhadap tingkat kecemasan ibu hamil multigravida trimester tiga dengan malaria ringan. Metode: Desain penelian yang digunakan adalah quasi experimental dengan rancangan pre-test post-test design dengan penelitian sebanyak 85 responden dengan tehnik consecutive sampling pada ibu hamil multigravida trimester tiga dengan malaria ringan di Puskesmas Timika, Puskesmas Timika Jaya, Puskesmas Pasar Sentral dan Puskesmas Wania di Kabupaten Mimika Provinsi Papua pada bulan November – Desember 2019 dengan menggunakan kuesioner Hamilton Anxiety Rate Scale (HARS) untuk mengukur tingkat kecemasan, kuesioner dukungan/keterlibatan suami untuk mengukur dukungan/keterlibatan suami terhadap kehamilan dan persiapan persalianan, kuesioner tingkat pengetahuan tanda dan bahaya malaria pada kehamilan. Memberikan edukasi tanda dan bahaya malaria dalam kehamilan. Analisis penelitian ini menggunakan uji Wilcoxon. Hasil uji statistik memperlihatkan bahwa terdapat perbedaan tingkat kecemasan pada ibu hamil dengan malaria sebelum dan setelah diberikan edukasi, dengan nilai rerata skor tingkat kecemasan cenderung menurun dari 21,54 menjadi 19,06, berada pada kecemasan sedang dan ringan. Kesimpulan: Ada perbedaan tingkat kecemasan ibu hamil setelah dilakukan edukasi dengan pendampingan suami
Sobre a matemática do ensino como objeto teórico de pesquisa
Authors: Valente Wagner Rodrigues , Luciane de Fatima Bertini
Published: June 2022

Os capítulos que seguem este primeiro intentam caracterizar “matemáticas”. Os estudos movem-se por elementos considerados fundamentais para a configuração da matemática do ensino. Tratam os capítulos de matemáticas a ensinar e de matemáticas para ensinar. Tais objetos teóricos construídos pela pesquisa histórica realizada pelos autores permitem a caracterização da matemática do ensino. Tal matemática relaciona objetos de trabalho do professor - a matemática a ensinar - com ferramentas que devem ser utilizadas pela docência - a matemática para ensinar.
To the issue of the classification of administrative and legal methods of fiscal control
Authors: Tatarova Tetiana , Sabluk Serhii , Chubenko Anton , Kozin Serhii , Kobylnik Dmytro
Published: June 2022

In the article, based on the analysis of scientific views of scientists and the norms of the current legislation, the scientific task, which is to establish a circle and classify the administrative and legal methods of fiscal control, is solved. The methodological basis for the article is a number of methods of scientific knowledge, including: logical and semantic, monographic, logical, dialectical methods, methods of analyses and synthesis, systematization and classification, method of summarization. The scientific novelty of the article is that it presents the author’s classification of methods of fiscal control. The results of the study can be used to conduct further research on fiscal control methods, enabling the scientists to develop their own classifications and generalizations of such methods. The originality of the article is that the proposed groups of fiscal methods, according to the view of the researches, are also divided into voluntary, voluntary and compulsory one, and strictly coercive ones.
Innovative potential of the consumer sector of the economy: financial, economic and legal aspects
Authors: Loiko Valeriia , Teremetskyi Vladyslav , Loiko Daria , Ivanova Anna , Pozdieieva Kateryna
Published: June 2022

The authors of the article have analyzed the legal, financial and economic aspects of the innovative capacity of the consumer sector of the national economy of Ukraine. The problems that slow down the process of forming the innovative capacity of the consumer sector of the national economy have been identified. The results of theoretical and methodological research of the essence of the innovative capacity of the consumer sector of the national economy have been presented. It has been offered to consider the following the most influential financial and economic aspects for the formation of the innovative capacity of the consumer sector of the national economy: the dynamics of issuing security documents for industrial property facilities in Ukraine; volumes and sources of financing of innovation activity in Ukraine; motivation to intensify innovation activity. It has been concluded that Ukraine has created a regulatory legal base for regulating innovation activity, but it needs further improvement and adaptation to European legislation. It has been determined that the innovative capacity of education as a component of the consumer sector of the national economy is influenced by several factors, namely: the dynamics of budget funding of general secondary educational institutions and the dynamics of changing in the number of such institutions. The authors have suggested the list of resources, which are expedient to involve at acceleration of the process of the formation of innovative capacity of the consumer sector of the national economy.
Judicial precedent and practice of the ECHR in criminal law
Authors: Jafarov Habib Rahim , Tsekhan Dmytro , Lutsyk Vasyl , Baranenko Dmytro
Published: June 2022

The source of law, the case-law of the European Court of Human Rights (hereinafter – the ECtHR), is playing an increasingly significant role in the practice of judicial proceedings in Ukraine. The activities of the ECtHR significantly affect the implementation of the principle of the rule of law in Ukraine in criminal proceedings. Therefore, the phenomenon of judicial precedent and the application of ECtHR practice in criminal law requires comprehensive analysis. The work aims to study the case law and practice of the ECHR in criminal law, problems of theory and practice of application of court precedents by national courts, and ways to solve them. The research methodology consists of such methods as historical and legal; comparative law; formal and logical; empirical; cognitive; method of analogy; synthesis method; method of analysis. The value of ECtHR decisions is that such decisions, more quickly than other criminal procedural means, make adjustments to the law enforcement process of public authorities, thus improving the mechanism of criminal procedural regulation to guarantee conventional and constitutional human rights. In addition, the recognition of the case law of the ECtHR as a source of law is necessary for the adaptation of national legislation of Ukraine to the legislation of the European Union. Although legal precedent is not officially recognized as a source of law in Ukraine, the decision of the ECtHR recognizing case law can be considered in Ukraine as a rule of law.
Innovative technologies as alternative means of improving the efficiency of criminal justice in Ukraine
Authors: Husieva Vlada , Avdieiev Oleksandr , Kornienko Volodymyr , Kryvoruchko Larysa
Published: June 2022

The purpose of the article is to study investigative and judicial practice, as well as international experience to determine the prospects for the introduction of innovative technologies in criminal justice in Ukraine in modern conditions, to reveal their capabilities in the context of improving investigative (investigative) actions and trials.

In order to achieve the goal of the article, a comparative legal method was used, which allowed to determine the internationally tested innovative methods of improving criminal justice. Methods of analysis and generalization have helped to identify current problems that arise in investigative and judicial practice, which can be solved through the introduction of modern forensic tools.

In the article, the authors argued that an alternative way to increase the efficiency of criminal justice in Ukraine is the introduction of innovative technologies that have been tested in some countries. Forensic innovations, the need for which is urgent now and the implementation of which is justified by the needs of investigative and judicial bodies of Ukraine, we include those aimed at automation, digitalization of pre-trial investigation and trial. Prospects for the introduction of an electronic system of expert opinions, artificial intelligence technologies, laser three-dimensional scanning are identified. The need to improve the electronic justice system was emphasized.
Autoavaliação na aprendizagem de programação introdutória: uma revisão sistemática da literatura / Self-assessment in introductory programming learning: a systematic literature review
Authors: Da Silva Bárbara Gabriela Sousa , Fontes Laysa Mabel de Oliveira , Freitas Brígido Conrado de Brito
Published: June 2022

O processo de aprendizagem de programação em cursos introdutórios é desafiador para alunos, professores e instituições de ensino, já que, devido a diversas dificuldades, os alunos tendem a evadir dos cursos por não se acharem capazes de aprender os conceitos de programação ou sentirem dificuldades durante seu aprendizado que não são supridas pelos professores. Diante desse contexto, este artigo busca, por meio de uma revisão sistemática da literatura, fazer um levantamento sobre o estado atual e as principais características da autoavaliação na aprendizagem de programação introdutória, para que os resultados levantados possam ser utilizados em contextos reais de sala de aula, com a finalidade de prover uma melhoria no processo de ensino e aprendizagem. O protocolo seguido, permitiu a busca de artigos em bases conhecidas na área de informática para educação, onde foram aplicados os critérios de inclusão e exclusão para posterior análise de qualidade e seleção final para leitura na íntegra desses estudos, para que assim, pudesse ser feita a extração dos dados que responderam às questões de pesquisa da obra. Os resultados apontam que nos últimos 5 anos: (i) a principal abordagem de autoavaliação utilizada foi o uso de feedback personalizado; (ii) a principal técnica utilizada foi o feedback; (iii) as principais limitações reportadas pelos autores foram limitações relacionadas à abordagem utilizada; (iv) dentre os benefícios, o que obteve mais relevância foi a melhoria na compreensão do conteúdo; (v) a abordagem de medição mais adotada foi a análise de performance; e (vi) as tecnologias que mais auxiliam no processo de autoavaliação, foram as ferramentas.
Educação infantil e pandemia COVID- 19: o que dizem as pesquisas / Early childhood education and pandemic COVID- 19: what the research says
Authors: Rodrigues Juliana Antônia Fraga dos Santos
Published: June 2022

No ano de 2019 foi identificado na China o primeiro caso do novo Coronavírus (Covid-19), que se espalhou rapidamente no mundo todo, chegando ao Brasil em 2020. Desde então as escolas começaram a oferecer uma modalidade de ensino emergencial para todos os alunos da educação básica. Esse trabalho objetiva analisar por meio de pesquisas o cenário da pandemia COVID-19 na Educação Infantil pública brasileira, tentando analisar por meio de referência bibliográfica e documental quais os impactos causados aos alunos desse nível de ensino nas escolas públicas brasileiras, no que se refere as consequências dessa modalidade emergencial. A pesquisa foi realizada com base em pesquisa bibliográfica e documental, a metodologia aplicada foi por meio de análises de documentos referentes a pandemia. Conclui-se que por meio de pesquisas bibliográficas que o período pandêmico nos afeta e deixará marcas na trajetória da educação das crianças, pois o ensino emergencial foi realizado sem as condições materiais necessárias e tampouco sem considerar as desigualdades presentes no Brasil. Uma série de discussões poderá então surgir a partir desse cenário, questões sobre como ficará o ensino dessas crianças? Os professores prestaram assistências a todas as crianças? Teve qualidade no ensino? As crianças aprenderam alguma coisa? Nesse momento o que podemos de fato afirmar é que a desigualdade social ficou mais visível e que muitas escolas com seu corpo docente se esforçaram ao máximo para que todas essas indagações fossem positivas e que mesmo assim não foi o suficiente.