bluuebunny/crossref_metadata_2025 huggingface dataset:
IDENTIFICAÇÃO E ANÁLISE DE PATOLOGIAS CONSTRUTIVAS EM UNIDADE EDUCACIONAL PÚBLICA DE PRESIDENTE EPITÁCIO, SP
Authors: Silva Lucas  Henrique  Pereira , Tamashiro Jacqueline  Roberta , Antunes Patrícia Alexandra
Published: June 2020

The inspection of pathologies in a building is necessary for the diagnosis of the state of conservation, the operating conditions, the prediction of lifetime and the prior identification of faults for possible maintenance projects. This paper identified and analyzed the pathological manifestations in the roof and ceramic coatingsof an educational building in Presidente Epitácio, São Paulo.The results indicated that the incorrect sizing of the rainwater system allowed the accessof humiditythat contributed to the early appearance of other pathologies. Moreover, wasfound ahigh degree of detachment of ceramics in the wet areas of the building, which requires furtherteststo determine their causes.
ABORDAGEM ODONTOLÓGICA EM PACIENTE PORTADOR DE LEUCEMIA LINFOIDE AGUDA: REVISÃO DE LITERATURA
Authors: Zocante Pricila Trindade , Silva Pedro Cardoso , Parizi Arlete Gomes Santos
Published: June 2020

The objective in this study wasanalyze information found inliterature that discussesthe need for dental evaluationsand assistance in patients with leukemia,so thata multiprofessional team can provide the patient with a less aggressive reality of the disease, treatment or maintenance.The present study was developed through documentary analysis of the bibliographic production obtained in the following databases: Virtual Health Library (VHL), LILACS, MEDLINE, PubMed and SciELO. Dental intervention reduces the frequency of problems, minimizing the risk of oral infections and associated complications. Therefore, the dental appointment of a newly diagnosed patient with leukemia should be done as soon as possible, so that there is sufficient time to take proper care before the start of cancer therapy. Although the dentist not being responsible for treating cancer is important in treating the oral complications of the diseases.
A Quantitative Approach to Analyze Modifiability in Software Architectural Design of Agile Application Systems
Authors: Philip Milu
Published: June 2020

The present-day software application systems require a high degree of agility during development and operational phases due to the advancements in software technologies and also because of the need to support the variation points in software architecture. A single architectural style will not be adequate for the architectural design of such application systems. This paper proposes a composite architectural style involving three different architectural styles, namely model view controller, pipes and filters and reflection architectural pattern. A metric to evaluate the extent to which the proposed architectural design is modifiable is defined and formulated. The number of direct connections between the components and their modes of operation are the various factors that will determine the extent to which the architectural design is modifiable. The model has been tested successfully for a prototype document processing application system. The composite architectural design is quite generic and it can be used for any real-time application system where the three modes of operation - data stream mode, user interaction and dynamic invocation mode exist together.
A Meminductor-based Chaotic System
Authors: Qi Aixue , Ding Lei , Liu Wenbo
Published: June 2020

We propose a meminductor-based chaotic system. Theoretical analysis and numerical simulations reveal complex dynamical behaviors of the proposed meminductor-based chaotic system with five unstable equilibrium points and three different states of chaotic attractors in its phase trajectory with only a single change in circuit parameter. Lyapunov exponents, bifurcation diagrams, and phase portraits are used to investigate its complex chaotic and multi-stability behaviors, including its coexisting chaotic, periodic and point attractors. The proposed meminductor-based chaotic system was implemented using analog integrators, inverters, summers, and multipliers. PSPICE simulation results verified different chaotic characteristics of the proposed circuit with a single change in a resistor value.
Multiclass Membership Determination Integrating an ID-Bound Method with Bloom Filter
Authors: Chen Lu-I , Ma Heng
Published: June 2020

Membership determination with classification is an essential function for a variety of applications, such as network routing and packet inspection. We aim to constitute a mechanism capable of performing such a service with the considerations of efficiency and error ratio issues. The proposed method employs an array structure, in which each unit composes of multiple bits. The array houses a circular bound representation and a Bloom filter, where the former encodes the members and makes judgments of queries, while the latter acts as a secondary means for programming cases indeterministic by the former. Experimental results show that the error ratios were competitive and consistent with different levels of classification, as well as the memory space utilized. The lookup time decreased as the memory space increased. We depict specific characteristics for tackling the problem, including simplicity of data structure for encoding the members, avoidance of checking all classification IDs in the lookup process, and adoption of an auxiliary means for improving the error ratios. The ID-bound method is novel, and with the Bloom filter as the assistant, the proposed approach is robust in performances of both efficiency and error ratio.
New Product Information Diffusion in Firm–Hosted Online Communities Based on User Influence
Authors: Zhang Jing , Guo Wei , Zhao Nan , Wang Jinliang , Wang Lei
Published: June 2020

The diffusion of new product information in firm–hosted online communities depends on the information interaction between users. Especially in the early stage of new product online sales, user influence based on interactive behavior is the critical factor that affects the wide and sustainable diffusion of new product information, makes users respond to firm’s announcement of new product releases in time, and improves the new product competitiveness. Since very little work has been done on the effect of user influence on the new product information diffusion, this paper proposes a model based on user influence for the diffusion of new product information in firm–hosted online communities to fill this gap. Moreover, focusing on the hot topics of new product innovation functions, we present a new method to measure user influence from the perspective of user interaction, which provides a quantitative theoretical basis for the diffusion probability of influencing user state change in new product information diffusion. Finally, our model tests a well–known firm–hosted online community in China. The results reveal that the model can effectively describe the dynamic evolution of information diffusion, explain the key dynamic factors, and accurately predict the peak time of information diffusion.
Richterliche Macht ohne richterliche Verantwortung: Warum es den Roboter-Richter nicht geben darf
Authors: Greco Luís
Published: June 2020

Neue technologische Durchbrüche im Bereich der künstlichen Intelligenz lassen in nicht allzu ferner Zukunft den Roboter-Richter erwarten. Der Beitrag legt dar, weshalb dieser Entwicklung widersprochen werden muss. „Computer können juristische Entscheidungen treffen und psychiatrische Urteile fällen. Sie können auf viel ausgesuchtere Weise Münzen werfen als das geduldigste menschliche Wesen. Der Punkt ist, daß ihnen solche Aufgaben nicht übertragen werden sollten.“
Schutz und Verantwortung in der digitalen und globalen Arbeitswelt
Authors: Kurt Simge
Published: June 2020

Die digitale und globale Arbeitswelt verbindet Elemente der Abhängigkeit und Unabhängigkeit. Die Herbeiführung eines angemessenen Ausgleichs zwischen Schutz und Freiheit gewinnt als Schutzzweck an Bedeutung. Das ermutigt zu einem Verständnis, das sich davon entfernt, das Arbeitsrecht auf ein „Schutzrecht“ zu reduzieren und dahin übergeht, dieses als „Schutz- und Verantwortungsrecht“ mit nach Effektivität zu bestimmenden Trägern zu begreifen. Dieser Herausforderung stellt sich die Dissertation. Sie konzentriert sich auf den Gesundheitsschutz, analysiert die Verschiebung von Abhängigkeiten und Freiheiten und nimmt am Beispiel der Selbstgefährdung eine rechtsbereichsübergreifende Annäherung mit Fokus auf das Arbeitsschutzgesetz vor.
Near-field Communication (NFC)
Authors: Singh Neeraj Kumar
Published: June 2020

Libraries are the central agencies for the dissemination of knowledge. Every library aspires to provide maximum opportunities to its users and ensure optimum utilization of available resources. Hence, libraries have been seeking technological aids to improve their services. Near-field communication (NFC) is a type of radio-frequency technology that allows electronics devices—such as computers, mobile phones, tags, and others—to exchange information wirelessly across a small distance. The aim of this paper is to explore NFC technology and its applications in modern era. The paper will discuss potential use of NFC in the advancement of traditional library management system.
Measuring the Impact of Digital Heritage Collections Using Google Scholar
Authors: Borrego Ángel
Published: June 2020

This study aimed to measure the impact of digital heritage collections by analysing the citations received in scholarly outputs. Google Scholar was used to retrieve the scholarly outputs citing Memòria Digital de Catalunya (MDC), a cooperative, open-access repository containing digitized collections related to Catalonia and its heritage. The number of documents citing MDC has grown steadily since the creation of the repository in 2006. Most citing documents are scholarly outputs in the form of articles, proceedings and monographs, and academic theses and dissertations. Citing documents mainly pertain to the humanities and the social sciences and are in local languages. The most cited MDC collection contains digitized ancient Catalan periodicals. The study shows that Google Scholar is a suitable tool for providing evidence of the scholarly impact of digital heritage collections. Google Scholar indexes the full-text of documents, facilitating the retrieval of citations inserted in the text or in sections that are not the final list of references. It also indexes document types, such as theses and dissertations, which contain a significant share of the citations to digital heritage collections.
A NOVEL HYBRID MODEL BY USING CONVOLUTIONAL NEURAL NETWORK AND LONG SHORT-TERM MEMORY FOR TEXT SENTIMENT ANALYSIS
Authors: MA XIAOHUI
Published: June 2020

Machine learning has been widely applied in sentiment analysis. However, natural language has a structure-dependent relationship, relying on a single network for feature extraction, which limits the precision of text sentiment classification. To extract semantic features and perform classification effectively, the convolutional neural network and long short-term memory model (CNN–LSTM) was proposed in the study. The Word2vec method was employed to train the initial word vector. The CNN convolutional layer and the max-pooling layer were introduced to extract the local features of the text. The LSTM module was adopted to capture the long-term dependencies between word sequences. The features extracted with LSTM and CNN were fused, and efficiency was improved using dropout regularization technology. A case study was performed on the movie review dataset to analyze the classification effect utilizing the traditional and proposed methods. Results demonstrate that compared with the single CNN and LSTM models, the evaluation index F1 of this model improves by 1.93% and 0.97%, respectively. Compared with the randomly initialized feature vector, the precision of the model improves 2.74% by the word embedding.The proposed method can receive parallel input of the text information, which reduces the training time of the network model. The mechanism combining CNN and LSTM compensates for the shortcomings of relying only on word embedding for feature extraction, enabling the model to obtain in-depth sentiment feature and effectively-identified sentiment polarity without external knowledge such as dependency syntax analysis. The proposed method provides a specific reference for the sentiment classification of comment texts in social media.

Keywords: Sentiment analysis, CNN, LSTM, Feature fusion
Kolonier ‘for Kirke og Folkelivets Vækst og Udvikling’ Spatial mediering af dansk-amerikansk grundtvigianisme i USA, ca. 1900
Authors: Larsen Tina Langholm
Published: June 2020

ENGLISH ABSTRACT: This article examines how the ethnoreligious immigrant organization Danish People’s Society utilized ethnic colonies as spatial mediums to promote and foster preservation of the Danish cultural and spiritual heritage in the USA. Informed by theoretical insights gained in the research fields of medium theory and human geography, I highlight place-naming and physical construction of the places as symbolic and material strategies employed by Danish People’s Society to establish the colonies as mediums. Based on the historical development of the colonies, the article argues that place-naming matters; place-naming may function as a powerful political and socially excluding act. In conclusion, I suggest that a more comprehensive understanding of the meaning, agency, and implications of spatial mediums requires that we approach these places as social, symbolic, and material constructions that are continually reconfigured and ascribed identity through interaction.

DANSK RESUMÉ: Med udgangspunkt i to tidligere dansk-amerikanske kolonier undersøger denne artikel, hvorledes den etnoreligiøse immigrantorganisation Dansk Folkesamfund benyttede sig af etniske kolonier som spatiale medier til at facilitere og generere dansk folkeoplysning og kulturarvsbevaring i USA. Ved brug af teoretiske indsigter fra forskningsfelterne ‘medium theory’ og humangeografi fremhæver jeg navngivning og fysisk bebyggelse af steder som en henholdsvis symbolsk og materiel strategi, hvormed Dansk Folkesamfund etablerede kolonierne som medier. Baseret på stedernes historiske udvikling argumenterer jeg, at navngivningen af fysiske steder bør tages seriøst; stednavngivning kan være en magtful politisk og socialt ekskluderende handling. På denne baggrund konkluderes det, at vi for at få en mere fyldestgørende forståelse af den betydning og agens samt de implikationer, spatiale medier kan have, må tilgå dem som både symbolske, sociale og materielle konstruktioner, der kontinuerligt rekonfigureres og tilskrives identitet gennem interaktion.
Multisygdom
Authors: Sodemann Morten
Published: June 2020

Multisygdom har altid eksisteret, men blev desmaskeret af hyperspecialiseringen i sundhedsvæsnet, der har gjort denne gruppe af patienter til et problem, de ikke var tidligere. Dét der opfattes som en epidemi af komplekse patienter, der skyl-ler ind over et forsvarsløst sundhedsvæsen, er i virkeligheden et problem, der primært blev skabt af en ukontrolleret hyperspecialisering, hvor præmissen er, at patienter har én sygdom.
Breve recorrido por los catálogos de exposiciones relacionadas con Picasso: 1900 – 2017
Authors: Ortiz Tello María
Published: June 2020

El catálogo expositivo actúa como resultado y testigo de la exhibición afín, estableciéndose como un elemento clave para su investigación cuando esta ya ha sido clausurada. En la actualidad son auténticos libros de arte, que no solo dejan constancia de una exposición conjunta, sino que van más allá, ofreciendo auténticas investigaciones de carácter científico. Pero no siempre fue así. Este tipo de publicación ha sufrido variaciones muy significativas a medida que transcurría el siglo XX. En este artículo se presenta un recorrido a través de su evolución, desde los primeros folletos hasta los grandes estudios actuales, tomando como ejemplo los catálogos de decenas de exposiciones que incluyen obras de Picasso, uno de los grandes artistas del siglo XX. De este modo, se expondrá las particularidades que han presentado los catálogos expositivos a lo largo de las décadas, y cómo han ido modificándose hasta alcanzar el grado de cientificidad actual.
Los fanales del Niño Jesús y la construcción simbólica de la virtud femenina en los monasterios de Córdoba del Tucumán (fines s. XVIII- comienzos s. XIX)
Authors: Scocchera Vanina
Published: June 2020

El presente trabajo se propone desarrollar un estudio de los fanales del Niño Jesús existentes en repositorios de la ciudad de Córdoba cuya procedencia de monasterios femeninos ha sido ampliamente documentada. No obstante, nuestra disciplina carece de investigaciones que aborden el estudio de estos objetos desde una perspectiva que responda a las sucesivas manipulaciones, apropiaciones y resignificaciones simbólicas y materiales que atravesaron a lo largo de su vida. Para responder a estos interrogantes, el presente trabajo se propone iniciar un estudio cultural de la vida cotidiana desplegada en dichos monasterios femeninos para comprender las prácticas de elaboración de dichos objetos, a la vez que, propone desarrollar un análisis iconográfico y material de sus elementos que nos permita comprender sus sentidos simbólicos, usos y funciones. En este sentido, el presente trabajo abordará los imaginarios construidos en torno de la virtud femenina como una meta a la que las monjas debían aspirar en un camino de perfección y dónde las prácticas contemplativas se entroncaron con las activas y, entre otros, dieron por resultante la elaboración de fanales del niño Jesús dotados de sentidos polisémicos y eficaces para recordar el destino asumido por estas monjas como mujeres virtuosas y sacrificiales.
The unlimited potential of the great pond snail, Lymnaea stagnalis
Authors: Fodor István , Hussein Ahmed AA , Benjamin Paul R , Koene Joris M , Pirger Zsolt
Published: June 2020

Only a limited number of animal species lend themselves to becoming model organisms in multiple biological disciplines: one of these is the great pond snail, Lymnaea stagnalis. Extensively used since the 1970s to study fundamental mechanisms in neurobiology, the value of this freshwater snail has been also recognised in fields as diverse as host–parasite interactions, ecotoxicology, evolution, genome editing and 'omics', and human disease modelling. While there is knowledge about the natural history of this species, what is currently lacking is an integration of findings from the laboratory and the field. With this in mind, this article aims to summarise the applicability of L. stagnalis and points out that this multipurpose model organism is an excellent, contemporary choice for addressing a large range of different biological questions, problems and phenomena.
Visualization and quantification of mimetic musculature via DiceCT
Authors: Dickinson Edwin , Atkinson Emily , Meza Antonio , Kolli Shruti , Deutsch Ashley R. , Burrows Anne M. , Hartstone-Rose Adam
Published: June 2020

The muscles of facial expression are of significant interest to studies of communicative behaviors. However, due to their small size and high integration with other facial tissues, the current literature is largely restricted to descriptions of the presence or absence of specific muscles. Using diffusible iodine-based contrast-enhanced computed tomography (DiceCT) to stain and digitally image the mimetic mask ofEulemur flavifrons(the blue-eyed black lemur), we demonstrate—for the first time—the ability to visualize these muscles in three-dimensional space and to measure their relative volumes. Comparing these data to earlier accounts of mimetic organization with the face of lemuroidea, we demonstrate several novel configurations within this taxon, particularly in the superior auriculolabialis and the posterior auricularis. We conclude that DiceCT facilitates the study these muscles in closer detail than has been previously possible, and offers significant potential for future studies of this anatomy.
Diversity and spoilage potential of microbial communities associated with grape sour rot in eastern coastal areas of China
Authors: Gao Huanhuan , Yin Xiangtian , Jiang Xilong , Shi Hongmei , Yang Yang , Wang Chaoping , Dai Xiaoyan , Chen Yingchun , Wu Xinying
Published: June 2020

As a polymicrobial disease, sour rot decreases grape berry yield and wine quality. The diversity of microbial communities in sour rot-affected grapes depends on the cultivation site, but the microbes responsible for this disease in eastern coastal China, has not been reported. To identify the microbes that cause sour grape rot in this important grape-producing region, the diversity and abundance of bacteria and fungi were assessed by metagenomic analysis and cultivation-dependent techniques. A total of 15 bacteria and 10 fungi were isolated from sour rot-affected grapes. High-throughput sequencing of PCR-amplicons generated from diseased grapes revealed 1343 OTUs of bacteria and 1038 OTUs of fungi. Proteobacteria and Firmicutes were dominant phyla among the 19 bacterial phyla identified. Ascomycota was the dominant fungal phylum and the fungi Issatchenkia terricola, Colletotrichum viniferum, Hanseniaspora vineae, Saprochaete gigas, and Candida diversa represented the vast majority ofmicrobial species associated with sour rot-affected grapes. An in vitro spoilage assay confirmed that four of the isolated bacteria strains (two Cronobacter species, Serratia marcescens and Lysinibacillus fusiformis) and five of the isolated fungi strains (three Aspergillus species, Alternaria tenuissima, and Fusarium proliferatum) spoiled grapes. These microorganisms, which appear responsible for spoiling grapes in eastern China, appear closely related to microbes that cause this plant disease around the world.
Prevalence and correlates of depressive symptoms among Chinese patients with cataracts treated in tertiary general hospitals
Authors: Liu Zhong-Hua , Chen Chang-Zheng , Gao Cong , Zhou De-Yi
Published: June 2020

Background

Previous studies recruited unrepresentative samples of Chinese patients with cataract and reported a wide range of prevalence of depressive symptoms in this patient population (18.0–89.7%). The present study determined the prevalence and correlates of depressive symptoms among a consecutive sample of Chinese patients with cataract treated in tertiary general hospitals.

Methods

A total of 339 patients with cataract were consecutively selected from ophthalmology departments of two large general hospitals in Wuhan, China. Depressive symptoms were assessed with the Chinese Hospital Anxiety and Depression Scale. Logistic regression was used to identify factors that were associated with depression.

Results

The prevalence of depressive symptoms was 23.9% (95% CI [19.4–28.4]%) among patients with cataract. Correlates for depressive symptoms include an education level of primary school and below (OR = 1.93, P = 0.038), marital status of “others” (OR =3.15, P < 0.001), poor family economic status (OR = 2.26, P = 0.010), nuclear cataract (OR =4.32, P < 0.001), and mixed cataract (OR = 2.76, P = 0.017).

Conclusions

Depressive symptoms are common among Chinese patients with cataract treated in large general hospitals. Patients who are poorly educated, have a marital status other than “married”, have poor family economic status, and suffer from nuclear and mixed cataracts are at greater risk for depressive symptoms.
Directoras de cine argentinas y españolas. Una década re-creando imaginarios
Authors:   Universidad de Sevilla (España), Núñez Domínguez Trinidad , Vera Balanza María Teresa ,   Universidad de Málaga (España)
Published: June 2020

Aunque el cine latinoamericano está muy afianzado, existen insuficientes estudios comparados. Este artículo presenta un inventario de directoras y películas argentinas y españolas, desde 2000 a 2010, un período marcado por el relevo generacional en la industria cinematográfica de ambos países y determinado por un contexto sociopolítico consolidado democráticamente y lastrado por los vaivenes económicos. El objetivo es doble: dar visibilidad a las realizadoras y a las temáticas que abordan, y valorar puntos de encuentro y divergencias entre temáticas y representaciones de la realidad. Como método se opta por un diseño descriptivo y la aplicación de un análisis comparativo, tanto cuantitativo como cualitativo. Se efectúa una recopilación, síntesis y correlación de obras y temáticas que alcanza un corpus de 72 directoras y 138 producciones. Los resultados muestran que existen hilos comunes que delatan la denuncia de situaciones no resueltas para las mujeres: la maternidad, la homosociabilidad femenina o las ideas sobre el amor y el sexo, la vivencia o el recuerdo de la represión, la violencia estructural del estado autoritario y las transformaciones de los modos de vida. Acusan diferencias en cuanto a los tiempos y oportunidades, los estilos y los géneros, propias de la coexistencia de trayectorias fílmicas diversas, pero creadoras todas de unos relatos que rompen con modelos sociales limitados y que se abren al compromiso social.
Stress and burnout in chiropractic students of European chiropractic colleges:
Authors: Rank Maike Perelló , de la Ossa Pablo Pérez
Published: June 2020

Objective

High levels of stress and burnout are known to negatively impact academic success, quality of life, and well-being of students. The purpose of this study was to investigate the degrees of stress and burnout levels of students from several European chiropractic colleges.

Methods

Stress and burnout were assessed using the Perceived Stress Scale (PSS-10) and the Maslach Burnout Inventory–Student Survey (MBI-SS). Surveys were delivered electronically in November 2017 to chiropractic students from 4 different chiropractic colleges. Data were analyzed using t test and 1-way ANOVA to determine differences between demographic data. Scores in perceived stress and burnout subscales were compared to the general, chiropractic, and medical student populations.

Results

Both the MBI-SS and PSS had similar response rates (30%–34%) and demonstrated statistically significant differences between institutions, with C-3 demonstrating the highest levels of exhaustion (p < .001) and the highest levels of perceived stress (p = .012). MBI-SS results show that in the general chiropractic student population, 26.4% presented high emotional exhaustion, 18.2% high cynicism, and 43.8% low academic efficacy. Meanwhile, the PSS score indicated “moderate” levels of stress.

Conclusions

European chiropractic students experience higher levels of perceived stress than the general population and they may suffer levels of burnout similar to those of medical students. These results suggest that colleges should monitor stress and burnout levels in their students. This may help to establish student support systems in order to improve students' quality of life and academic performance, as well as help new graduates transition to their professional lives.
USO DO KAHOOT E DE ESTRATÉGIA DE GAMIFICAÇÃO NO ENSINO SUPERIOR: relato de experiência da aplicação do peer instruction como metodologia de ensino
Authors: Cavaignac Selma
Published: June 2020

O objetivo do presente artigo é relatar aplicação de uma metodologia ativa de ensino, em específico o método Peer Instruction, com uso da plataforma Kahoot e estratégia didática de gamificação. O Kahoot foi utilizado para inserir um recurso tecnológico interativo que se apropria de elementos dos jogos, buscando engajar os alunos na aprendizagem. A experiência foi desenvolvida em uma turma de 1º período, de um curso de Jornalismo, em uma universidade de São Luís – Maranhão, durante o primeiro semestre de 2019. A metodologia utilizada foi o estudo de caso. A pesquisa foi aplicada para 35 alunos da disciplina de Processos e Técnicas de Jornalismo. Ao final, foi aplicado um questionário eletrônico da Microsoft Forms, com perguntas abertas e fechadas. Concluiu-se que o método Peer Instruction, criado há mais de 20 anos, pode ser aplicado com o uso de recursos e estratégias de aprendizagem diversificadas, que dinamizem a construção do conhecimento e estejam em sintonia com o atual contexto de transformação da educação. A participação ativa dos alunos em sala de aula, aliada aos depoimentos positivos em relação ao método adotado, mostram que é possível modificar a dinâmica de sala aula utilizando as novas tecnologias e ferramentas de comunicação para reelaborar os métodos de ensino, aumentando a interação e a motivação dos alunos.
A CURADORIA DIGITAL COMO MEIO DE PRESERVAÇÃO E DIFUSÃO DA COLEÇÃO DE TESES E DISSERTAÇÕES DO INSTITUTO MILITAR DE ENGENHARIA
Authors: Belchior Vanessa Ferreira , Hollós Adriana Cox
Published: June 2020

Este artigo tem o objetivo de propor a utilização da curadoria digital como meio de difundir e preservar a coleção de teses e dissertações do Instituto Militar de Engenharia. Insere-se no contexto atual tendo em vista que se refere aos debates sobre a preservação da produção científica acadêmica na área de ciência e tecnologia e parte do pressuposto que não há futuro sem passado, ou seja, a preservação, neste caso, digital faz-se necessária. Caracteriza a importância do acervo do Instituto Militar de Engenharia - IME, que foi a primeira escola de engenharia das Américas e terceira do mundo, assim como faz uma análise sobre alguns marcos teórico-conceituais como repositórios institucionais, preservação digital e curadoria digital. Apresenta dados consolidados em relação ao acervo da Biblioteca General Armando Ferreira Dubois e todas as publicações ali contidas. Por fim conclui que o Instituto Militar de Engenharia necessita preservar sua produção acadêmica através de um projeto de digitalização em curso para que assim este material seja disponibilizado no repositório institucional do Exército Brasileiro, a Biblioteca Digital do Exército - BDEx, alcançando assim a preservação de seu acervo científico e seguindo as normas e padrões nacionais e internacionais que garantem a acessibilidade, integridade, confiabilidade e a disseminação da informação.
ROS Scavenging Biopolymers for Anti‐Inflammatory Diseases: Classification and Formulation
Authors: Zhang Jianhua , Fu Yu , Yang Peng , Liu Xianhu , Li Yiwen , Gu Zhipeng
Published: June 2020

Reactive oxygen species (ROS), the byproducts of aerobic metabolism, is a class of crucial molecules in physiological processes, nevertheless, would induce a series of inflammatory responses when overexpression. Excessive or inappropriate inflammation contributes to a range of acute and chronic human inflammatory diseases. In recent years, ROS scavenging agents have been widely regarded as a kind of potential therapeutic substances due to their abilities of delaying and/or inhibiting the oxidative stress in physiological microenvironments. ROS scavenging biopolymers are a group of agents that commonly have strong ROS scavenging ability and pharmacokinetic potential compared to similar low molecular weight agents. In this review, the generation and clearance of ROS in physiological processes, as well as the effects of ROS inflammatory diseases are introduced. Furthermore, the classification, macromolecular structure, and scavenging mechanism of those antioxidant polymers are systematically described and discussed, which aim to provide a guiding theoretical reference of designing effectively ROS scavenging biopolymers for anti‐inflammatory disease therapy.
Light Tracking and Light Guiding Fiber Arrays by Adjusting the Location of Photoresponsive Azobenzene in Liquid Crystal Networks
Authors: Liu Li , del Pozo Marc , Mohseninejad Fateme , Debije Michael G. , Broer Dirk J. , Schenning Albert P. H. J.
Published: June 2020

The integration of light tracking and light guiding within fiber arrays is an intriguing challenge. In this study, an advanced drop casting/drawing method is applied to fabricate a fiber array capable of not only performing sunflower‐inspired light tracking, but also light guiding. The fiber arrays are constructed with various liquid crystal networks by adjusting the location of photoresponsive azobenzene moieties in the polymer network to understand the correlation between the extent of photoresponse and azobenzene location. Incorporating the azobenzene in the main chain oligomer renders these fibers with advanced photoresponse in both air and water. The fibers are able to track a light source and to guide the collected light, making these responsive actuator arrays potentially attractive for advanced photovoltaic and optical elements.
Iron‐Promoted Domino Dehydrogenative Annulation of Deoxybenzoins and Alkynes Leading to β‐Aryl‐α‐Naphthols
Authors: Zhu Xue‐Qing , Guo Rui‐Li , Zhang Xing‐Long , Gao Ya‐Ru , Jia Qiong , Wang Yong‐Qiang
Published: June 2020

A strategy for synthesis of β‐aryl‐α‐naphthols has been established through an iron‐promoted domino C(sp3)−H/C(sp)−H and C(sp2)−H/C(sp)−H dehydrogenative coupling of deoxybenzoins and alkynes. The synthesis uses inexpensive materials with a broad substrate scope and features simple operations with excellent regioselectivity. This study provides an alternative access to various β‐aryl‐α‐naphthols and the synthetic protocol should have potential applications in medicinal, materials science, and related areas.

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Gas–liquid–solid reaction system for CO2 electroreduction to formate without using supporting electrolyte
Authors: Díaz‐Sainz Guillermo , Alvarez‐Guerra Manuel , Solla‐Gullón José , García‐Cruz Leticia , Montiel Vicente , Irabien Angel
Published: June 2020

The use of bismuth‐based catalysts is promising for formate production by the electroreduction of CO2 captured from waste streams. However, compared to the extensive research on catalysts, only a few studies have focused on electrochemical reactor performance. Hence, this work studied a continuous‐mode gas–liquid–solid reaction system for investigating CO2 electroreduction to formate using Bi‐catalyst‐coated membrane electrodes as cathodes. The experimental setup was designed to analyze products obtained in both liquid and gas phases. The influence of relevant variables (e.g., temperature and input water flow) was analyzed, with the thickness of the liquid film formed over the cathode surface being a key parameter affecting system performance. Promising results, including a high formate concentration of 34 g/L with faradaic efficiency for formate of 72%, were achieved.
Flow characteristics of blade unit of a tridimensional rotational flow sieve tray under concurrent gas–liquid flow
Authors: Wang Hongkai , Tang Meng , Wang Dewu , Liu Yan , Zhang Yishuo , Hu Baisong , Wang Ruojin , Zhang Shaofeng
Published: June 2020

The flow characteristics of the blade unit of a tridimensional rotational flow sieve tray were investigated. First, the flow patterns are defined under different liquid arrangement methods. They are bilateral film flow, continuous perforated flow, and dispersion‐mixing flow in overflow distribution, film and jet flow and jet and mixed flow in spray distribution. Second, the time and frequency domain analysis of the differential pressure pulsation signal in the blade unit is carried out, the main frequencies range is 2.0−5.5 Hz. The influence of perforation and mixing intensity on the flow pattern transition is clarified. Third, the rotational flow ratio of the gas–liquid phase is measured, the gas phase rotational flow range is 0.55–0.78, and the liquid phase range is 0.15–0.42. The influence of the operating conditions on the distribution of the rotational and perforated flow is investigated. Finally, a prediction model for the rotational flow ratio is proposed.
Salivary lactoferrin as biomarker for Alzheimer's disease: Brain‐immunity interactions
Authors: Bermejo‐Pareja Félix , del Ser Teodoro , Valentí Meritxell , de la Fuente Mónica , Bartolome Fernando , Carro Eva
Published: June 2020

Objective

We aim to explain why salivary lactoferrin (Lf) levels are reduced in patients suffering mild cognitive impairment (MCI) and sporadic Alzheimer's disease (sAD).1 We also will discuss if such Lf decrease could be due to a downregulation of the sAD associated systemic immunity.

Background

Several non‐neurological alterations have been described in sAD, mainly in skin, blood cell, and immunological capacities. We reviewed briefly the main pathophysiological theories of sAD (amyloid cascade, tau, unfolder protein tau, and amyloid deposits) emphasizing the most brain based hypotheses such as the updated tau‐related neuron skeletal hypothesis; we also comment on the systemic theories that emphasize the fetal origin of the complex disorders that include the low inflammatory and immunity theories of sAD.

New/updated hypothesis

Lf has important anti‐infectious and immunomodulatory roles in health and disease. We present the hypothesis that the reduced levels of saliva Lf could be an effect of immunological disturbances associated to sAD. Under this scenario, two alternative pathways are possible: first, whether sAD could be a systemic disorder (or disorders) related to early immunological and low inflammatory alterations; second, if systemic immunity alterations of sAD manifestations could be downstream of early sAD brain affectations.

Major challenges for the hypothesis

The major challenge of the Lf as early sAD biomarker would be its validation in other clinical and population‐based studies. It is possible the decreased salivary Lf in early sAD could be related to immunological modulation actions, but other different unknown mechanisms could be the origin of such reduction.

Linkage to other major theories

This hypothesis is in agreement with two physiopathological explanations of the sAD as a downstream process determined by the early lesions of the hypothalamus and autonomic vegetative system (neurodegeneration), or as a consequence of low neuroinflammation and dysimmunity since the early life aggravated in the elderly (immunosenescence).
Further understanding the connection between Alzheimer's disease and Down syndrome
Authors: Snyder Heather M. , Bain Lisa J. , Brickman Adam M. , Carrillo Maria C. , Esbensen Anna J. , Espinosa Joaquin M. , Fernandez Fabian , Fortea Juan , Hartley Sigan L. , Head Elizabeth , Hendrix James , Kishnani Priya S. , Lai Florence , Lao Patrick , Lemere Cynthia , Mobley William , Mufson Elliott J. , Potter Huntington , Zaman Shahid H. , Granholm Ann‐Charlotte , Rosas H. Diana , Strydom Andre , Whitten Michelle Sie , Rafii Michael S.
Published: June 2020

Improved medical care of individuals with Down syndrome (DS) has led to an increase in life expectancy to over the age of 60 years. In conjunction, there has been an increase in age‐related co‐occurring conditions including Alzheimer's disease (AD). Understanding the factors that underlie symptom and age of clinical presentation of dementia in people with DS may provide insights into the mechanisms of sporadic and DS‐associated AD (DS‐AD). In March 2019, the Alzheimer's Association, Global Down Syndrome Foundation and the LuMind IDSC Foundation partnered to convene a workshop to explore the state of the research on the intersection of AD and DS research; to identify research gaps and unmet needs; and to consider how best to advance the field. This article provides a summary of discussions, including noting areas of emerging science and discovery, considerations for future studies, and identifying open gaps in our understanding for future focus.
Mapping the Insula with Stereo‐Electroencephalography: The Emergence of Semiology in Insula Lobe Seizures
Authors: Singh Rinki , Principe Alessandro , Tadel Francois , Hoffmann Dominique , Chabardes Stéphan , Minotti Lorella , David Olivier , Kahane Philippe
Published: June 2020

Objective

Insula epilepsy is rare and can be evaluated effectively by Stereotactic intracerebral EEG (SEEG). Many previous studies of insulo‐opercular seizures have been unable to separate insular and opercular onset. With adequate sampling of the insula, this study shows this is possible.

Methods

We analyzed intrainsular dynamics and extrainsular propagation in 12 patients with “pure” insula epilepsy (n = 9) or insular and only deepest opercular involvement (n = 3) at seizure onset. Review of semiology defined clinical groups, agglomerative cluster, and principal component analysis of semiological features were performed. Quantitative epileptogenicity, and intrainsular and extrainsular propagation were computed via time frequency analysis and epileptogenicity mapping.

Results

Seizure onset patterns were heterogeneous; the seizure onset zone was focal. Seizure onset and first ictal change within insula functional subdivision correlated with aura and reflex component. No paninsular spread occurred; contralateral insular spread was very early. While the discharge was intrainsular, clinical signs related to aura or vegetative signs. Extrainsular propagation was early and related to the emergence of the majority of clinical signs. Cluster analysis found an anterior, intermediate, and posterior insula seizure onset group. The largest principal component separated anterior insula manifestations, including early hypermotor signs, early recovery, and no aura from posterior insula features of early dystonia, early tonic motor features, and sensorimotor aura.

Interpretation

Aura is vital to identifying seizure onset and relates to insula functional subdivision. Seizures are heterogenous; extrainsular propagation occurs early, accounting for most of the semiology. With adequate sampling, "pure" insula epilepsy can be identified and focal curative resection is possible. ANN NEUROL 2020;88:477–488
Study on the liquid crystal display mask photo‐curing of photosensitive resin reinforced with graphene oxide
Authors: Xie Jiaqing , He Yunsheng , Ma Wenqiang , Liu Tao , Chen Jun
Published: June 2020

Graphene oxide has the characteristics of high specific surface area, high strength, and high modulus. The tensile and compressive properties of the cured resin part can be reinforced after the graphene oxide is mixed into the photosensitive resin. A self‐developed liquid crystal display (LCD) mask photo‐curing machine is adopted to prepare photosensitive resin parts mixed with graphene oxide. The influence of graphene oxide content on the surface roughness, tensile, and compressive properties of the cured resin is analyzed by the combination of finite element simulation and experiment. It is concluded that the accumulation of graphene oxide is the main reason affecting the tensile and compressive properties of the cured part. By applying ultrasonic vibration and extending the time of magnetic stirring at 80°C, the dispersion uniformity of graphene oxide is improved, the agglomeration of graphene oxide is reduced, and the tensile and compressive strength of cured parts are strengthened.
Extreme Greenland blocking and high‐latitude moisture transport
Authors: Barrett Bradford S. , Henderson Gina R. , McDonnell Erin , Henry Major , Mote Thomas
Published: June 2020

Blocked atmospheric flows over Greenland and the North Atlantic Arctic (NAA) can be defined by the appearance of an anomalous ridge, many times off the western margin of continents, that deflects traveling cyclones from their usual storm tracks. Atmospheric blocking often produces a strong equatorward deflection of polar air on the eastern flank of the anticyclone, including severe cold episodes in winter, and severe droughts and heat waves in summer. Recent changes in low‐frequency atmospheric circulation in the NAA have increased sensible heat and moisture advection from the mid‐latitudes into this region. In this study, we explore the frequency and seasonality of extreme Greenland blocking, and we explore the relationship between extreme blocking and moisture transport into and over the region.

We quantify atmospheric flow blocking over Greenland using the Greenland Blocking Index, and extreme blocking is defined from 1980 to 2019 at the 90th, 95th, 97th, and 99th percentiles for both summer (June to August) and winter (December to February) seasons. Moisture transport over Greenland was defined by calculating daily integrated vapor transport from the ERA‐Interim reanalysis over the region from 15° to 85°W and 55° to 80°N. The frequency of extreme blocking over Greenland was found to have increased in the most recent two decades (2000–2019) compared to the period 1980–1999. In addition, the probability of above‐average moisture transport occurring on a day with extreme blocking is high in both summer and winter, with the highest probability of high moisture transport during an extreme Greenland Blocking Index day in winter. These findings are unique to this work and suggest future work on the role of moisture transport in developing or sustaining blocks over Greenland.
Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population-based study
Authors: Väyrynen V , Wirta E-V , Seppälä T , Sihvo E , Mecklin J-P , Vasala K , Kellokumpu I
Published: June 2020

Background

This population-based study aimed to examine the incidence, patterns and results of multimodal management of metastatic colorectal cancer.

Methods

A retrospective population-based study was conducted on patients with metastatic colorectal cancer in Central Finland in 2000–2015. Clinical and histopathological data were retrieved and descriptive analysis was conducted to determine the pattern of metastatic disease, defined as synchronous, early metachronous (within 12 months of diagnosis of primary disease) and late metachronous (more than 12 months after diagnosis). Subgroups were compared for resection and overall survival (OS) rates.

Results

Of 1671 patients, 296 (17·7 per cent) had synchronous metastases, and 255 (19·6 per cent) of 1302 patients with resected stage I–III tumours developed metachronous metastases (94 early and 161 late metastases). Liver, pulmonary and intraperitoneal metastases were the most common sites. The commonest metastatic patterns were a combination of liver and lung metastases. The overall metastasectomy rate for patients with synchronous metastases was 16·2 per cent; in this subgroup, 3- and 5-year OS rates after any resection were 63 and 44 per cent respectively, compared with 7·1 and 3·3 per cent following no resection (P < 0·001). The resection rate was higher for late than for early metachronous disease (28·0 versus 17 per cent respectively; P = 0·048). Three- and 5-year OS rates after any resection of metachronous metastases were 78 and 62 per cent respectively versus 42·1 and 18·2 per cent with no metastasectomy (P < 0·001). Similarly, 3- and 5-year OS rates after any metastasectomy for early metachronous metastases were 57 and 50 per cent versus 84 and 66 per cent for late metachronous metastases (P = 0·293).

Conclusion

The proportion of patients with metastatic colorectal cancer was consistent with that in earlier population-based studies, as were resection rates for liver and lung metastases and survival after resection. Differentiation between synchronous, early and late metachronous metastases can improve assessment of resectability and survival.