bluuebunny/crossref_metadata_2025 huggingface dataset:
OPTIMIZING HVAC EFFICIENCY AND RELIABILITY: A REVIEW OF MANAGEMENT STRATEGIES FOR COMMERCIAL AND INDUSTRIAL BUILDINGS
Authors:   Master of Engineering Management, College of Engineering, Lamar University, Beaumont, Texas, USA, Islam Muhammad Mohiul , Shofiullah Shaikh ,   Master of Engineering Management, College of Engineering, Lamar University, Texas, USA, Sumi Sayeda Sufia ,   Master of Industrial Engineering, College of Engineering, Lamar University, Beaumont, Texas, USA, Shamim CM Ariful Haque ,   Master of Electrical Engineering, College of Engineering, Lamar University, Beaumont, Texas, USA
Published: October 2024

This study presents a comprehensive review of strategies to optimize HVAC systems in commercial and industrial buildings, focusing on enhancing energy efficiency, system reliability, and environmental sustainability. HVAC systems are major energy consumers, contributing significantly to operational costs in large buildings. With increasing energy costs, regulatory pressures, and the push for sustainability, technological advancements and management strategies have emerged to improve HVAC performance. Following PRISMA guidelines, this review analyzed 58 high-quality peer-reviewed studies published between 2010 and 2023. Key findings show that energy management systems (EMS) can reduce energy consumption by up to 30%, while Building Management Systems (BMS) enhance system reliability through centralized control and predictive maintenance. The adoption of eco-friendly refrigerants and energy-efficient designs, such as heat recovery and variable refrigerant flow (VRF) technologies, further lowers energy usage and environmental impact. Additionally, integrating renewable energy sources like solar and geothermal into HVAC systems can reduce energy consumption by as much as 40%. Green building certifications, such as LEED and BREEAM, drive the adoption of optimized HVAC technologies, delivering both environmental and financial benefits. This review underscores the crucial role of HVAC optimization in reducing energy consumption, lowering carbon footprints, and improving the operational performance of buildings, offering valuable insights for building managers, engineers, and policymakers.
"THE YEAR OF SOLIDARITY FOR A GREEN WORLD" IS THE RESULT OF A GREAT POLITICAL COURSE OF AN IRREPLACEABLE LEADER
Authors: Cəfərova İnarə
Published: October 2024

The article is devoted to the pressing issue of environmental problems that have always been in the attention of the great leader. The main goal of the environmental policy implemented in Azerbaijan is the efficient use of natural resources to meet the needs of current and future generations. Consistent actions and work in this area have given impetus to achieving new successes in the field of ecology and environmental protection.
THE IMPACT OF EVENTS HELD IN CONNECTION WITH “THE YEAR OF SOLIDARITY FOR A GREEN WORLD” ON THE FORMATION OF BEHAVIORAL CULTURE IN PRESCHOOL CHILDREN
Authors: Məmmədova Kifayət
Published: October 2024

The article talks about the factors influencing the formation of preschoolers' behavior towards living and inanimate nature, ecological culture, and the characteristics of ecological culture. In this regard, in connection with the announcement of 2024 as the "Year of Green World Solidarity" in the Republic of Azerbaijan, the article provides detailed information on the formation of skills and feelings of nature con¬servation, respectful attitude and love for it, as well as projects and events held in a number of preschool ed¬ucational institutions of our republic. It should be noted that educators and teachers of preschool educational institutions benefit from the content and structure of such events held in our republic and operating in a net¬work mode, practical examples that they apply in the course of various activities, as well as the involvement of parents in this work, turns children into active participants in the process, and in them lives and cares for inanimate nature, protects greenery, cares for it, etc. creates the basis for the formation and development of ethical skills.
LITERARY ENVIRONMENT OF SHUSHA
Authors: İbişov Aydın
Published: October 2024

The article provides information on the study of the literary environment of Shusha. The literary environment of Shusha originates from this rich source. As elsewhere in Azerbaijan, the first literary samples were created in Karabakh by Russian poets, which is reflected in the works of poets and writers. Shusha is not only the cultural center of Azerbaijan, but also the birthplace of outstanding and talented personalities, artists, writers, composers, singers.
ARMENIA'S ECOLOGICAL TERRORISM AGAINST AZERBAIJAN
Authors: Əkbəri Təranə
Published: October 2024

Since 1988, 20% of Azerbaijan's lands have been occupied as a result of the war waged by Armenia to pursue its territorial claims against Azerbaijan. After a long occupation, during the 44-day Patriotic War and 24-hour local anti-terrorist operations, our lands, which had been in the hands of the enemy for almost 30 years, were liberated by our brave Army. However, in the territories we liberated from occupation, the enemy left behind ruins and an environmental disaster. For almost 30 years, Armenia deliberately tried to destroy our nature, carried out environmental terrorism against Azerbaijan, spontaneously exploited natural resources, including our occupied territories, polluted drinking water reservoirs with industrial waste, and disrupted the ecological balance of the environment. During the occupation, the enemy committed the great¬est acts of vandalism on our lands; the occupying forces destroyed forests, national parks, nature reserves, valuable trees and other rare examples of biodiversity. The rivers that are the source of Azerbaijan's drinking water are contaminated with chemical, biologi¬cal and other radioactive waste flowing from the territory of Armenia. Over the past years, contamination of water sources flowing from the occupied territories has led to the death of valuable fish species and the depletion of fish stocks. 7 ecologically important relic lakes and 10 reservoirs in the liberated territories of Azerbaijan were subject to serious anthropogenic impact from the occupying Armenia.
ACOMPANHAMENTO DE PACIENTES PORTADORES DE CIRROSE HEPÁTICA E OS DESAFIOS DA GESTÃO
Authors: Braga Christiane Lourenço , Alves Gabriel Ferreira Braga , Almeida Isis Santos da Costa de , Castro Manuella Villela Vaz Moreira de , Bonorino Natália Camilo , Pereira Nicole Gondim , Hernandes Rebecca Almeida Anselme , Rojas Yasmin Lorennza Gusmão , Araújo Andrea de Paula Barros , Ribeiro Wanderson Alves
Published: October 2024

Introduction: Liver cirrhosis is a chronic condition in which liver cells are destroyed or compromised, leading to the formation of scars, nodules or fibrosis. This factor contributes to a decrease in the partial or total functioning of the organ. Objectives: The main objective of this study was to investigate the challenges faced by management in the treatment and monitoring of patients with liver cirrhosis. Methodology: This is an integrative review of the literature searched in the following databases: PUMED and Virtual Health Library (VHL/SCIELO) between the years 2019 to 2023. Results: After the search and selection according with the inclusion and exclusion criteria, 09 articles were selected to compose this study. Conclusion: Public management faces challenges related to the shortage of specialized professionals, unequal distribution of these professionals and limited financial resources, along with restrictions on organs for liver transplantation. To face such obstacles, it is vital to prioritize the integration of health services, the efficient allocation of resources and the implementation of policies that raise awareness among the population about the causes and importance of early detection of the disease. These measures aim to ensure timely and effective treatment, in addition to improving the quality of life of patients with liver cirrhosis.
ANÁLISE DA PERCEPÇÃO DE PAIS E RESPONSÁVEIS SOBRE A EQUOTERAPIA PARA CRIANÇAS COM AUTISMO: UMA REVISÃO DA LITERATURA DE 2013 A 2023.
Authors: Souza Camila Fernanda de , Moreira William da Costa , Luz Larissa Djanilda Parra da
Published: October 2024

Equine therapy brings numerous benefits to practitioners, improving motor, cognitive, and emotional development. Due to this range of contributions, doctors and multidisciplinary teams recommend equine therapy as an alternative therapy, especially for children with autism spectrum disorder due to its benefits. Animal-assisted therapy has been demystified over time and has become the option for caregivers and/or parents. The basis of the scientific study will be basic research with a bibliographic review of the literature. Objective: The project is based on the bias of presenting the perception of parents and/or guardians of children diagnosed with autism in relation to the care process offered by an equine therapy center. Method: It used the Integrative Literature Review (ILR) in six stages, addressing everything from problem definition to critical data analysis. Articles in Portuguese and Spanish from 2013 to 2023 were included, using the LILACS, PubMed, and Google Scholar databases with descriptors related to equine therapy and autism. Results: Indicate that equine therapy provides significant benefits, such as increased self-esteem, improvements in socialization, anxiety control and development of social skills. The research highlights the importance of the bond between practitioners and animals, as well as the fundamental role of the multidisciplinary approach in treatment. Parents in all reviewed studies reported improvements in the quality of life of practitioners. Conclusion: Equine therapy shows itself to be a promising therapy for children with Autism Spectrum Disorder, contributing significantly to the development of self-esteem, mental health, social skills, emotional control and independence. Parents' perceptions are fundamental to understanding the effectiveness of these therapies, but reveal gaps when compared to professionals' views. This highlights the need for research on the topic.
MANEJO DO PACIENTE ONCOLÓGICO PRÉ E PÓS RADIOTERAPIA DE CABEÇA E PESCOÇO COM AUXÍLIO DA LASERTERAPIA NA CICATRIZAÇÃO E NO TRATAMENTO DAS MUCOSITES: RELATO DE CASO
Authors: Cardoso Ana Paula Oliveira , Melo Tiago Teixeira , Nascimento Arací Loorany Loiola do , Chagas Murilo Fernandes Ferreira , Heimlich Fernanda Vieira , Santos Júnior João Pereira dos
Published: October 2024

Dental treatment for patients with head and neck cancer before and after treatment continues to be extremely important due to the impacts caused by the disease and the effects of its treatment, which in turn end up debilitating the health of these patients. In these cases, patients may present with oral and oropharyngeal mucositis and osteoradionecrosis, which are complications of head and neck radiotherapy. The aim of this paper is to report the clinical case of a 65-year-old male patient diagnosed with Non-Keratinizing Squamous Cell Carcinoma in the left parotid region. The patient sought dental care at the Dentistry Clinic of Faculdade São Lucas in Porto Velho – RO, referred for multiple extractions prior to chemotherapy and radiotherapy treatment. During intraoral inspection, it was possible to observe very poor oral hygiene, periodontal disease, fractured teeth, biofilm and dental caries. Surgical planning was therefore carried out for the extraction of 11 teeth in two sessions. In order to achieve this objective, the method used was the clinical case and a bibliographic review of scientific articles published in the last ten (10) years, without language restrictions, and indexed on the following search sites: PUBMED, ScientificElectronic Library (SciELO) and Google Scholar using the following keywords: “cancer patient”, “mucositis”, “laser therapy” and “head and neck radiotherapy”. Of all the articles found using the strategy described above, only twenty (20) met the inclusion and exclusion criteria.
O EMPREGO DO CANABIDIOL NA TERAPÊUTICA DO TRANSTORNO DO ESPECTRO AUTISTA: REVISÃO SISTEMÁTICA
Authors: Quintino Aliny de Jesus , Quintino Bianca de Jesus , Pimenta Carlos Eduardo Souza , Rodrigues Sayma Caldas , Souza Mariana Menezes , Sousa Maryana Gomes de , Moreira Sara Ribeiro , Peixoto Samuel Silva , Eguchi Victor Mesquita , Fagundes Valéria de Castro
Published: October 2024

Objective: To analyze the applicability of cannabidiol in the complementary treatment of Autism Spectrum Disorder. Methods: The present work is characterized as a systematic literature review, which was carried out by searching for studies available in the Google Scholar, MedLine, PubMed and SciELO indexers. Results: 163 articles were found on the researched platforms, of which 19 were included for full reading and 11 were chosen to be part of the literature review. Conclusion: The effectiveness of cannabidiol as a complementary therapy for ASD is concluded, as long as it is indicated and monitored by a medical professional. However, it appears that drugs derived from Cannabis are not free from adverse effects, requiring assessment of their long-term safety profile.
EFEITOS DOS EXERCÍCIOS NA MELHORA DA DOR PACIENTES COM FIBROMIALGIA: REVISÃO INTEGRATIVA
Authors:   Nathalya Caitano Silva, Braga Júnior Ademir Pereira ,   Waueverton Bruno Wyllian Nascimento Silva
Published: October 2024

FM is a complex rheumatic condition characterized by chronic pain without evident inflammation. It primarily affects women between the ages of 55 and 74, impairing quality of life due to pain, fatigue, sleep disturbances, and emotional symptoms. Objective: To identify and report the effects of physical exercise on pain improvement in patients with FM. Methodology: An integrative literature review was conducted using the PICo strategy, covering primary studies from randomized clinical trials published between 2019 and 2024. The search was carried out in the LILACS, PubMed, SciELO, and PEDro databases, focusing on the benefits of exercise in pain management. The inclusion criteria were limited to full-text articles in Portuguese and English. Results: A total of 642 studies were analyzed, of which 9 were included in the final sample. These studies showed that aerobic, resistance, aquatic, and stretching exercises significantly contributed to the reduction of pain and fatigue. Additionally, there was an improvement in sleep quality, functional capacity, and emotional well-being, with a decrease in symptoms such as anxiety and depression. However, some studies did not show statistically significant results. Conclusion: It is concluded that physical exercise, when supervised and adjusted to individual needs, is an effective intervention in the management of fibromyalgia, providing pain relief and improving quality of life. Further studies are needed to investigate the interaction of exercises with other treatments, such as pharmacotherapy, and to evaluate long-term effects.
INCLUSÃO DOS ALUNOS TEA NA AULAS DE EDUCAÇÃO FÍSICA
Authors: Oliveira Irinaldo Carlos de
Published: October 2024

The inclusion of students with Autism Spectrum Disorder (ASD) in Physical Education classes is a topic of growing relevance and interest in the field of inclusive education. The present study aims to carry out a literature review on this topic, analyzing the current state of research, identifying gaps in knowledge and providing insights for effective inclusive practices. The justification for this study lies in the importance of promoting an education accessible to all students, regardless of their abilities and needs, and Physical Education plays a fundamental role in this process. The methodology used was a literature review, which involved searches in academic and institutional databases using descriptors related to the topic. The selected studies were critically analyzed to identify patterns, trends and gaps in the literature on the inclusion of students with ASD in Physical Education classes. It is concluded that the effective inclusion of students with ASD in Physical Education classes faces significant challenges, but is essential to ensure their full participation in school and society, promoting a more inclusive and accessible education for all.
TRATAMENTO DE INFECÇÕES ODONTOGÊNICAS: DA ABORDAGEM AMBULATORIAL AO MANEJO HOSPITALAR- UMA REVISÃO DE LITERATURA
Authors: Valente Rafael Jorge , Filippetti Nicholas Pascuotte , Kiyochi Júnior Hélio de Jesus , Marinho Kelly Cristine Tarquinio , Alves Levy Anderson Cesar , Harmitt Débora Dias da Silva
Published: October 2024

Introdução: As infecções odontogênicas representam um desafio clínico significativo na prática odontológica, com potencial para evoluir de quadros localizados a complicações sistêmicas graves, como a Angina de Ludwig e mediastinite. Esta revisão visa abordar as evidências recentes sobre o manejo dessas infecções, explorando o manejo ambulatorial e hospitalar. Métodos: A revisão de literatura foi realizada utilizando as bases de dados Google Acadêmico, PubMed e periódicos indexados no Journal Of Infection e Science Direct. Os termos de busca incluíram “infecções odontogênicas”, “complicações”, “antibioticoterapia” e “manejo”. Foram incluídos 19 artigos em inglês e português publicados nos últimos cinco anos, além de três livros de referência em Cirurgia e Traumatologia Bucomaxilofacial. Objetivo: O objetivo desta revisão é analisar criticamente as abordagens terapêuticas atuais para o tratamento de infecções odontogênicas, com foco em manejos para minimizar complicações graves e melhorar o desfecho clínico dos pacientes, tanto de maneira ambulatorial, quanto hospitalar. Discussão: A revisão revelou divergências entre os autores sobre as abordagens mais eficazes para o manejo das infecções odontogênicas, particularmente em relação ao uso de antibioticoterapia e intervenções cirúrgicas. Enquanto alguns autores defendem uma abordagem cirúrgica agressiva para evitar complicações graves, outros ressaltam a importância de adaptar a antibioticoterapia com base em culturas microbiológicas para prevenir resistência bacteriana. Também há variações na recomendação sobre o uso de antibióticos, refletindo a complexidade do manejo dessas infecções e a necessidade de uma abordagem personalizada. Conclusão: As infecções odontogênicas continuam a representar um desafio significativo na odontologia, exigindo uma abordagem diagnóstica e terapêutica abrangente. O reconhecimento precoce e o tratamento adequado são fundamentais para prevenir complicações e promover a recuperação da saúde. A revisão enfatiza a necessidade de uma abordagem integrada e atualizada no manejo dessas infecções
PROSES MANAJEMEN DAN ADMINISTRASI DI DEPARTEMEN PERENCANAAN DAN PENGADILAN, DIVISI HARKAN, PT. PAL INDONESIA
Authors: Siti Anisah  , Radjikan
Published: October 2024

Praktik Kerja Lapangan adalah salah satu mata kuliah wajib yang harus ditempuh mahasiswa semester tujuh jurusan administrasi negara FISIP UNTAG Surabaya. Mata kuliah ini membekali mahasiswa pengetahuan tentang kegiatan pendidikan dan pelatihan dengan bekerja secara langsung, secara sistematik dan terarah dengan supervisi yang kompeten. Tujuan penelitian ini adalah : 1) Untuk mengetahui pengelolaan sumber daya manusia Divisi Harkan di PT PAL Indonesia, 2) untuk mengetahui proses administrasi di Divisi Harkan. Metode penelitian ini adalah kualitatif deskriptif. Penelitian dilaksanakan di Divisi Harkan PT. PAL Indonesia. Hasil penelitian diperoleh : 1) Proses alur bisnis Divisi Harkan sudah berjalan sesuai dengan ketentuannya, 2) Pengalokasian pegawai sudah teralokasikan sesuai dengan kebutuhan personil yang ada, 3) Proses administrasi bisnis/ organisasi Divisi Harkan sudah berjalan dengan baik.
Results of electrocardiography in children born at very early preterm birth
Authors: Zakharova S. Yu. , Pokusaeva O. S.
Published: October 2024

Background. Children born at extremely early preterm birth (EPL) are at high risk of developing cardiovascular diseases, including heart rhythm disorders (HRDs) and conduction disorders throughout life.

Objective: To study electrocardiographic features in children of the first year of life born at term SPR.

Materials and methods. The main group consisted of 51 children born at term. Depending on body weight, the main group was divided into 2 subgroups. Subgroup 1 consisted of children weighing 500-750 g (n=15). Subgroup 2 — children weighing 751 g or more (n=36). The comparison group included 28 children born at a gestational age of 32-36 weeks. Children were examined at the ages of 6 and 12 months. Electrocardiography was performed on children at rest in 12 standard leads with a paper tape speed of 50 mm/sec. Analysis of ECG indicators was carried out using a Sicard electrocardiograph from Siemens AG, according to generally accepted methods.

Results and discussion. In children born at gestational age during 1 year of life, clinical manifestations of impaired functional state of the cardiovascular system were observed in the form of vegetative-vascular dysfunction, NSR, and changes in the characteristics of heart sounds. According to the ECG results, NSR was identified in the form of sinus arrhythmia, sinus tachy- and bradycardia, extrasystole, atrial rhythm, pacemaker migration, supraventricular paroxysmal tachycardia, WPW syndrome, long QT interval syndrome, which amounted to 86.7% of cases in children of subgroup 1, in children of the 2nd subgroup 82.2% and 60.7% in children of the comparison group. A direct strong correlation has been established between the clinical manifestations of autonomic dysfunctions at the age of 12 months and the frequency of identified dysfunctions. By 12 months of life, the number of children with sinus bradycardia, sinus arrhythmia and ectopic rhythm increases. There is no positive trend in the frequency of detection of ECG phenomena during the first year of life.

Conclusion. Children born at very early preterm birth require cardiac monitoring, including blood pressure measurement, electrocardiography and the development of personalized clinical follow-up programs.
Gestational diabetes mellitus as a predictor of health disorders and lipid metabolism in newborns and infants (literature review)
Authors: Zakharova S. Yu. , Deryabina E. G. , Ladoshina K. S.
Published: October 2024

Background. Diseases of the endocrine system in their mothers, namely gestational diabetes mellitus (GDM), have a significant impact on the increase in morbidity in newborns. The main adverse outcome for children of mothers with GDM is macrosomia, as prenatal exposure to hyperglycemia increases the risk and programs the oﬀspring to develop diabetes and/ or obesity in adulthood.

Objective. To summarize modern scientific ideas about the impact of GDM on immediate and long-term disorders of health and lipid metabolism in newborns and young children.

Material and methods. An extensive literature review was conducted using the MEDLINE database (PubMed) using keywords and filter: randomized controlled trial, meta-analysis, systematic review.

Research results. This review summarizes the main evidence on the impact of maternal hyperglycemia on the health of her child and provides new information on the role of GDM in lipid disorders in newborns and young children.

Conclusion. Children born to mothers with GDM have an increased risk of developing obesity and impaired glucose tolerance from a very early age and throughout all periods of child-hood. Maternal hyperglycemia aﬀects both during pregnancy and the rate of physical development of children in early life. These studies are important given that neonatal fat, rather than birth weight, is an important risk factor for the development of obesity later in life.to summarize modern scientific ideas about the eﬀect of GDM on immediate and long-term disorders of health and lipid metabolism in newborns and young children.
Effect of glucagon-like peptide 1 receptor agonists on oral hormonal contraception (literature review)
Authors: Deryabina E. G. , Melkozerova O. A.
Published: October 2024

Background. Glucagon-like peptide 1 (GLP-1) is an incretin hormone whose mechanism of action also includes a slight delay in gastric emptying (GE). Due to the prevalence of type 2 diabetes mellitus and obesity, GLP-1drugs are prescribed to many patients, including women of reproductive age who are also taking COCs. For oral contraceptives, malabsorption may result in ineﬀective pregnancy prevention.

The purpose of this literature review was to review data from studies on the eﬀect of GLP-1 agonists on oral hormonal contraceptives (COCs) and to analyze data on the safety of concomitant use of COCs and GLP-1 agonists.

Methods. PubMed and ClinicalTrials.gov were searched for publications using keywords. A total of 3 clinical studies were selected for inclusion in the literature review.

Results. Studies involving GLP-1 have not revealed a statistically or clinically significant difference in drug-drug interactions with COC drugs.

Conclusion. This review compared the eﬀects of currently available GLP-1 on COCs in three clinical studies. Due to the prevalence of type 2 diabetes and obesity, GLP-1 is likely to be prescribed to many patients, including women of reproductive age who are also taking COCs. These drugs may aﬀect the pharmacokinetics of COCs. Changes in the area under the curve, maximum concentration, and time to maximum plasma concentration of oral drugs can be avoided by taking these drugs 1 hour after GLP-1.
Features of the functional state of the endothelium and the hemocoagulation system in the formation of placental insufficiency in patients with gestational diabetes mellitus without insulin requirement
Authors: Sytykh O. N. , Putilova N. V. , Tretyakova T. B.
Published: October 2024

Background. There is a lot of data in the literature showing the state of the hemostatic system and endothelium separately in patients with gestational diabetes mellitus (GDM) and placental insuﬃciency (PI). However, with the combination of the above complications of pregnancy, there is very little research, therefore, the problem requires detailed study.

Objective. To determine the contribution of the functional state of the endothelium and the hemocoagulation system to the formation of placental insuﬃciency in patients with gestational diabetes mellitus without insulin requirement.

Materials and methods. A longitudinal cohort comparative study was conducted. The study included 120 patients in the II-III trimester of pregnancy with GDM without insulin requirement. The main group consisted of 70 women whose pregnancy was complicated by sub- and decompensated forms of PN. The comparison group included 50 pregnant women without pathology of the fetoplacental complex. The hemostasis system was studied using clotting tests and thromboelastometry. The concentrations of VEGF-A, total nitrite (NO2 total), endogenous nitrite (NO2 endogenous), nitric oxide (NO) in peripheral blood were determined by ELISA. Comparison of continuous quantitative data was carried out using the Mann-Whitney test, which was calculated using the MedCalc 15.8 application program. The null hypothesis was rejected at p<0.05.

Result. The value of the integral index of coagulation, onset time and initial speed of clot formation in the main group was statistically significantly higher than in patients in the comparison group, p<0.05. The level of VEGF-A in pregnant women of the main group was statistically significantly lower than that in the comparison group, p<0.05. The indicator of total NO2 and NO in the main group was statistically significantly lower than in the comparison group, p<0.05. The endogenous NO2 indicator did not diﬀer statistically significantly between groups.

Conclusion. In patients with GDM on diet therapy and PN, endothelial dysfunction and, as a consequence, hypercoagulation occur.
Features of the course of external genital endometriosis due to cervical pathology
Authors: Avseenko M. A. , Timerchanova E. О. , Melkozerova O. A. , Mikhelson A. A.
Published: October 2024

Background. In modern literature, there is a limited number of publications devoted to the characteristics of the course of endometriosis in patients with cervical diseases (CD), the choice of management tactics for cervical diseases and the prevention of relapses of these diseases.

Objective. To analyze clinical, anamnestic and laboratory data in patients of reproductive age with a combination of benign cervical diseases and external genital endometriosis.

Materials and methods. A retrospective cohort study was conducted that included 100 women of reproductive age with external genital endometriosis. The main group consisted of 56 patients with a combination of benign cervical diseases and external genital endometriosis. The comparison group consisted of 44 patients with external genital endometriosis without cervical cancer. An assessment was made of clinical and anamnestic data, the results of a cytological examination of a cervical smear, extended colposcopy and the level of hormones AMH, FSH, estradiol, performed by enzyme immunoassay on days 2-5 of the menstrual cycle. Statistical analysis was carried out using the SPSS Statistics 26.0 program.

Results. External genital endometriosis in 56% of cases is associated with benign cervical diseases, in the structure of which non-inflammatory diseases predominate (63%). Inflammatory diseases of the cervix were observed in 16% of patients, and combined pathology of the cervix was observed in 21% of women with external genital endometriosis. The presence of concomitant cervical pathology in 83.3% of cases is accompanied by endometriosis-associated infertility, this is significantly more common than in patients with inflammatory (22.2%) and non-inflammatory (42.9%) cervical diseases, p < 0.05. Surgical treatment of endometriosis did not lead to pregnancy within one year after surgery in any planning patient with concomitant cervical pathology (0/11); this figure in women with non-inflammatory cervical diseases was 14.3% (4/32), whereas in 75.0% (3/4) with inflammatory diseases of the cervix, pregnancy occurred within a year after surgery, p<0.05. In turn, the presence of inflammatory cervical diseases was associated with a significantly lower level of AMH (1.4±0.5 ng/ml) compared to patients with non-inflammatory cervical diseases (3.0±0.4 ng/ml) and combined cervical cancer pathology (3.4±0.5 ng/ml), p<0.017. A significant decrease in ovarian reserve in the future can also lead to impaired fertility in this category of patients.

Conclusion. The results of the study indicate the need for a comprehensive assessment of the condition of the cervix in patients with genital endometriosis, including a thorough history taking, cytological examination and extended colposcopy in combination with determination of HPV virus carriage. Timely measures for the diagnosis and treatment of cervical diseases in patients with endometriosis-associated infertility will improve fertility rates in this category of patients.
Dijitalleşme ve eğitimde yapay zekâ: Eğitim yönetimine yansımaları
Authors: Polat Murat
Published: October 2024

Bu akademik görüş yazısında dijitalleşmenin ve yapay zekâ (YZ) teknolojilerinin eğitim yönetimi üzerindeki etkileri ele alınmıştır. Özellikle YZ’nin, veri tabanlı karar destek sistemleri aracılığıyla eğitim liderlerine sunduğu fırsatlar ve karşılaşılabilecek zorluklar tartışılmıştır. Eğitim yönetiminde YZ kullanımının, stratejik karar alma süreçlerinde verimliliği artırdığı, kişiselleştirilmiş öğrenme fırsatları sağladığı ve öğrenci performansını izlemeye katkı sunduğu belirtilmiştir. Bununla birlikte, teknolojik eşitsizlikler, veri gizliliği ve etik sorunlar gibi zorlukların da sürecin önemli unsurları olduğu ifade edilmiştir. Bu bağlamda, YZ’nin eğitimde sürdürülebilir kalkınmaya katkısı ve eğitim politikalarıyla uyumlu bir şekilde nasıl entegre edileceği tartışılmıştır.
YESUS DI GETSEMANI SEBAGAI UNGKAPAN CINTA AGAPE (REFLEKSI TEOLOGIS MATIUS 26:36-46
Authors: Parhusip Bintang , Situmorang Kalaudius Willy R.
Published: October 2024

The focus of this paper is to explain agape love through the story of the passion of Jesus in Gethsemane. Matthew 26:36-46 tells of Jesus prayer in Gethsemane as a model for building agape love. The methodology used in this research is a literature study to explore the theological reflections on Matthew 26:36-46 and its relation to the love of Peter and Judas. The passion story of Jesus shows the journey of eros love to agape love. The scheme of the triple prayer in Gethsemane shows the transformation of Jesus love. At the last point, Jesus was able to let go of everything and surrender to the will of the Father. This is the real proof of agape love, namely total obedience and self-sacrifice. This agape love is what Jesus passed on to Peter and Judas. Both have free will to choose, Peter chose to die for faith in Christ while Judas chose to despair and commit suicide. Peter was able to achieve agape love while Judas was entangled in eros love. The story of Peter and Judas becomes the foundation for the faithful to live love more deeply. Human life is a journey of love, namely from eros love to agape love which is Jesus himself.
PARADIGMA GABE-AUFGABE DALAM PERUMPAMAAN YESUS TENTANG TALENTA DAN RELEVANSI PASTORAL BAGI UMAT KRISTIANI
Authors: Senda Siprianus S.
Published: October 2024

Jesus' sermon in Matthew 24-26 is part of what is called a sermon about the end of time. One of the sermons in this section is the sermon on talents in chapter 25:14-30. This sermon has a rich theological meaning as a lesson for the Christian faithful. This paper attempts to explore the richness of the theological passages about this sermon and draw its relevance to the lives of the Christian faithful. The method used is the method of literature with a descriptive analysis approach to find theological messages based on the interpretations of experts. The results of the study show that the Gabe-Aufgabe paradigm is very strong in this parable as a form of life learning for Christians in managing God's grace according to His will for the goodness and salvation of Christians as followers of Christ.
MENGKAJI PEMAHAMAN UMAT TENTANG LITURGI SABDA DALAM PERAYAAN EKARISTI DI PAROKI SANTO YOSEPH NAIKOTEN KEUSKUPAN AGUNG KUPANG
Authors: Rusae Yohanes
Published: October 2024

The celebration of the Eucharist is central to all Catholic life. There are four parts to the celebration of the Eucharist: the Opening Rites, the Liturgy of the Word, the Liturgy of the Eucharist, and the Closing Rites. In the Liturgy of the Word there are readings of Scripture, psalms, homilies and prayers of the people. People believe that Christ Himself speaks through His Word. In this research the author uses a qualitative research method using content analysis in which problems or findings in the field are verified with empirical data. Researchers use a descriptive level of explanation, so that they hear more input from informants as a data source in order to find the root of the problem. The results of this research show that the people do not properly appreciate the celebration of the liturgy of the Word because the main inhibiting factor is the absence of catechesis or socialization about the Liturgy of the Word and also the lack of awareness within the people about the Liturgy of the Word in the Eucharist Celebration. So, from the results of this research, it is hoped that the parish can provide outreach regarding the liturgy of the Word for the people.
Celebrando 15 Años de Difusión del Conocimiento Marítimo: Revista Derrotero, Promoviendo la Conciencia Naval y Fluvial
Authors: Gómez Torregrosa Cedrid
Published: October 2024

Presentamos con mucho gusto el número diecisiete de la Revista Derrotero, de la Escuela Naval de Cadetes “Almirante Padilla”, en la que colaboran autores y evaluadores comprometidos en promover la conciencia marítima, fluvial y costera en nuestro país bioceánico y plurifluvial.
Den har så månne ywwn
Authors: Bøggild-Andersen Boel
Published: October 2024

Indeholder også "Fra Jysk Ordbogs trykmanuskript".
On taxation of small business in the context of integration of new regions
Authors: Pianova Marina Vladimirovna
Published: October 2024

The subject of the study is the mechanism of tax support for small businesses from the perspective of successful adaptation of taxpayers of southwestern subjects to the tax conditions of the Russian Federation. The paper examines the peculiarities of taxation of small businesses in the Donetsk and Lugansk People's Republics, Zaporizhia and Kherson regions, identifies some specific features of the development of small business in regions with high-risk conditions of activity. The hypothesis is formulated that changes in tax legislation regarding the simplified taxation system, which come into force on 1.01.2025, may be extremely negative for the absolute majority of taxpayers in the analyzed regions. The author focuses on the need to introduce temporary norms aimed at maintaining the level of tax burden of small businesses, even in conditions of low budget provision of new subjects of the Russian Federation, along with traditional methods of scientific analysis, such methods as a retrospective analysis of the development of small businesses; analysis of forms of statistical tax reporting of the Federal Tax Service of Russia; elements of the modeling method – for forecasting the performance indicators of taxpayers and the tax burden in the event of changes in tax legislation In the course of the study, the following tasks were solved and the relevant conclusions were formulated: - the dynamics of the number of small businesses in the southwestern regions of the Russian Federation is analyzed; it is determined that the growth rate of the number of taxpayers significantly exceeds the national average, while almost 80% of taxpayers belong to micro-businesses; - the specifics of taxation of small businesses in new territories and its impact on the level of tax burden are studied taxpayers. It has been revealed that the tax burden of SMEs in the new subjects of the Russian Federation is significantly lower than in regions with a comparable level of "subsidization" due to the introduction of reduced regional tax rates and a reduced tariff of insurance premiums; - assumptions are formulated that the new norms of the Tax Code of the Russian Federation regarding taxpayers of the USN may be the reason for a significant increase in the tax burden of small businesses; - separate recommendations have been formulated on the introduction of temporary tax measures that ensure the preservation of the tax burden and promote integration processes.
Analysis of the strategies of China and the United States in Central Asia: a look at the "C5+1" mechanism
Authors: Cao Huan
Published: October 2024

The subject of the study is a comparison of the policy of China and the United States in the Central Asian region within the framework of the "C5+1" model. Both the United States and China, being the major powers of the modern world, seek to protect their interests in this region. In addition to existing bilateral and multilateral dialogue platforms, the United States and China have established a C5+1 dialogue mechanism with Central Asia. This mechanism has developed differently in both countries, each of which has created its own unique model and achieved a number of diplomatic results. The methodological basis of this research consists in an integrated historical and sociological approach. The authors used a historical approach to analyze the main factual information covered in the article as a whole. The innovation of this article is to scrutinize and compare the development of the “C5+1” model in China and the United States. The conclusion is that each US government has its own strategic priorities and diplomatic plans, the US “C5+1” mechanism has developed unevenly. Compared with the US mechanism, China's mechanism is more complete and at the same time has a higher level. Both China and the United States have developed their strategies in Central Asia according to their own interests, and that the main goal of the United States' current Central Asian strategy is to create a counterweight to Russia and China. For China, preserving sovereignty and stability as well as economic development are its primary interests.
Assessment of genetic stability of micropropagated Curculigo latifolia from Indonesia by RAPD and ISSR
Authors: Muslihatin Wirdhatul , Saputro Triono Bagus , Wibowo Anjar Tri , Manuhara Yosephine Sri Wulan
Published: October 2024

Micropropagation of Curculigo latifolia is very important because this plant has high economic value including containing Curculin and Neoculin as sweetener and taste-modifying proteins. Micropropagated plants may experience genetic changes like somaclonal variation so it is necessary to assess their genetic stability. The purpose of this study was to obtain a micropropagation method of C. latifolia that is more efficient than the previous research and to assess the genetic stability of micropropagated C. latifolia. The plant material used was sterile leaves obtained from sterile seedlings raised from C. latifolia seed germination. Leaves were grown on a callus induction medium containing 5 mg l−1 indole-3-butyric acid and 3 mg l−1 BA in a dark room. Callus formed were subcultured to growth selection medium and shoots formed were subcultured to Murashige and Skoog-free growth regulator medium with the addition of 6 g l−1 agar and 3% sucrose. The cultures were incubated at 23ºC ± 2ºC under 1,500 lux white LED (PhilipTM TL) on a 16 hour/8 hour light/dark photoperiod. The cultures were incubated for 14 weeks. Genetic stability of in vitro propagated C. latifolia from Indonesia was assessed by molecular markers, RAPD and ISSR. The micropropagation method produces an efficient protocol because each growth stage occurs in a free growth regulator medium except for callus induction. Based on the results of the assessment using molecular markers, no polymorphism in DNA amplification using RAPD and a high percentage of genetic stability (66.67%) from ISSR analysis were obtained. In sum, the in vitro micropropagation protocol created can be used commercially to produce C. latifolia on a large scale that is genetically stable.
Isolation and identification of indigenous lactic acid bacteria with inhibitory activity against Aeromonas hydrophila in Vinh Long province
Authors: Quach Thi Van Cao , Nguyen Thuy Phuong , Truong Tat Quoc , Trung Nguyen Bao
Published: October 2024

Aeromonas hydrophila is a common cause of hemorrhagic disease that seriously harms several economically valuable farmed fish species in Vietnam and worldwide. Therefore, the objective of this investigation was to isolate and identify indigenous lactic acid bacteria (LAB) strains that inhibit the growth of A. hydrophila, causing hemorrhagic illness in farmed striped catfish in Vinh Long province. This finding yielded a total of 45 isolates of LAB from the intestine of healthy pangasius catfish. Using the well diffusion agar method, the results showed that 30 out of 45 isolated LAB strains (66.67%) had antibacterial activity against A. hydrophila. Among them, 10 out of 30 strains (33.33%) had strong activity, 15 out of 30 strains (50%) showed moderate activity, and 5 out of 30 strains (16.67%) exhibited weak activity, with mean inhibition diameters of 18.8 ± 3.52, 12.02 ± 1.32, and 5.89 ± 0.73 mm, respectively. With the exception of lipase activity, the enzyme activities of proteases and amylases were found in strain TMT1. Phylogenetic analysis using the 16S rRNA gene sequence showed that strain TMT1 was identified as Lactobacillus casei. The results of the research indicate that isolate TMT1 may be used to produce probiotics that help prevent pangasius hemorrhagic sickness.
Colonization pattern of arbuscular mycorrhizal fungi in invasive plant species of tropical dry deciduous forest of Belgahna range of Central India
Authors: Gautam Sakshi , Chaurasia Bhaskar
Published: October 2024

Arbuscular mycorrhizal fungi (AMF) are the key factor for the growth of plants in nature. In the present study, 10 common invasive plant species and one native dominant tree species Tectona grandis were selected to understand the colonization pattern of AMF in the roots. Rhizosphere soil and root samples of selected invasive plant species were taken from the Tropical Dry Deciduous Forest of Belgahna Range of Bilaspur district, Chhattisgarh. The roots were observed under a microscope followed by clearing with KOH and staining with lactophenol cotton blue. In all invasive plant species and in T. grandis, arbuscular mycorrhizal (AM) colonization was more than 85% (89.00 ± 1.70 to 97.70 ± 0.88). All three morphological types of AM colonization, i.e., Arum-type, Paris-type, and Intermediate-type were observed in all samples. The shape of vesicles ranged from irregular to rounded shape. Different intra-radical vesicles’ sizes and shapes suggested that different species of AM fungus had colonized roots. In most of the samples, vesicles were mostly irregular in shape, elliptical, oval, spherical, and rectangular, indicating the dominance of Acualospora spp. and Glomus spp. The present study, regarding the occurrence of AM fungi in 10 invasive plants and 1 native plant T. grandis will provide basic information on the diversity of AM colonization patterns, which may be utilized to understand the interaction between AMF and invasive plant’s roots. The similarity in colonization patterns in invasive and native species shows that AMF association may be one of the reasons for the existence and proliferation in the Tropical Forest of the Central region.
Optimizing cultivation conditions for enhanced productivity Limnothrix planctonica through pH variation and light quality
Authors: Chamarat Prachaya , Sanevas Nuttha
Published: October 2024

The survival and growth of cyanobacteria in diverse environments are influenced by several critical factors when cultivating them for research or industrial purposes. Ensuring their optimal growth necessitates consideration of these factors that potentially impede pigment and biomass production. Therefore, optimizing light conditions and pH levels enhances biomass and pigment yield productivity in cyanobacterial cultivation. This study investigates the cultivation conditions of Limnothrix planctonica (KU.B3) in a BG-11 liquid medium, focusing on pigment production, growth response to light and pH variations, and photosynthetic efficiency assessment. Results demonstrated efficient growth of L. planctonica (KU.B3) under white, orange, and red light within the pH range of 7.4–9.0. Cultivation at pH 7.4, yielded the highest biomass (3.59 ± 0.35 μg ml−1) and phycocyanin content (0.016 ± 0.01 mg g−1 dry weight). Red light-induced significant phycocyanin yield (5.49 ± 1.21 mg g−1 dry weight), while white light promoted substantial biomass production (10.03 ± 1.28 μg ml−1). Conversely, exposure to blue light reduced biomass but exhibited the highest photosynthetic efficiency (Fv / Fm = 0.48 ± 0.06). The study underscores the tradeoff between productivity and photosynthetic efficiency, emphasizing the need for further research to optimize conditions for both parameters, especially for industrial-scale applications.