bluuebunny/crossref_metadata_2025 huggingface dataset:
Al-‘Alāmah al-Tijāriyyah wa Ḥimāyatuhā fī al-Qānūn al-Indūnīsī: Dirāsah Fiqhiyyah Taqwīmiyyah
Authors: Haq Husnul , Arif Arif Ali
Published: February 2021

The trademark plays an important role in economic life, as it is a way for the merchant to distinguish his products from those produced by others. It also helps consumers to identify the products they want. Therefore, the countries of the world have agreed to conduct agreements to protect it, on top of which is the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS). When the State of Indonesia agreed to sign this agreement, it had to provide legal cover in the field of the trademark. The research aims to demonstrate trademark protection in Indonesian law and Islamic jurisprudence. This research falls within the library search, and its description is an analytical and critical description. After careful consideration, the research concludes that Indonesian law and Islamic jurisprudence are in agreement of considering the trademark as property and right. So, they agree on the necessity of trademark protection and imposing the punishment for the aggressor. Meanwhile, they differ in the imprisonment; the law considers it as a basic punishment while Islamic jurisprudence considers it as a secondary punishment
Trade in-Game Meat in Jagaraga Village, West Lampung from an Islamic Law Perspective
Authors: Sandriansyah Sandriansyah , Qiftiyah Maratul
Published: February 2021

This study aims to see the legal status of the game meat trade in Islamic law. This type of research is field research, using observation and interviews with hunters and players who buy and sell game meat. Trading in-game meat must not violate religious and state regulations. This paper finds that hunting and trading animal meat in the field against protected animals is prohibited by Islamic law. Hunting needs to be supervised by those who care so that the ecosystem is well preserved.
Comparison of anaerobic phosphorus release from activated sludge with three carbon sources
Authors: Dai Xiaohu , Gu Zhanbei , Dai Lingling , Shen Changming , Zhou Wei , Huang Jihui , Wang Wei , Liu Zhigang
Published: February 2021

Three carbon sources, namely sodium acetate, sewage and effluent, were used to simulate the process of phosphorus release in an actual sewage treatment plant, in order to explore the phosphorus release performance of the sludge, the relationship between phosphorus release and chemical oxygen demand (COD) in sewage, and the stability of phosphorus-rich sludge. The results showed that the type and concentration of carbon sources had significant effects on the rate of phosphorus release, reaction equilibrium time and phosphorus release amount. When sodium acetate was used as the carbon source, the phosphorus release rate reached 12.54 mg P (g VSS·h)−1, and tended to be stable at 4.0 hours. The phosphorus release amount in the first 2.5 hours accounted for 36.88% of the total phosphorus in the sludge. When sewage was used as the carbon source, the phosphorus release rate did not reach equilibrium even at 5.0 hours, and the phosphorus release amount increased by 1.0 mg L−1 for every 10.5 mg L−1 increase sewage COD within a certain range. When effluent was used as the carbon source, the visual phosphorus release amount was only 0.83 mg L−1 after standing for 24 hours and the actual phosphorus release amount was 17.98 mg L−1. These conclusions can provide technical support for the optimization of phosphorus removal in sewage treatment plants.
Capital cultural y trayectorias de migración interna de estudiantes de recién ingreso a la universidad Veracruzana
Authors: Suárez Domínguez José Luis , Vasquez Feria Alim Getze Mani Eden
Published: February 2021

En este artículo abordamos el perfil migratorio de los estudiantes de nuevo ingreso a las universidades. Los desplazamientos estudiantiles han sido reconocidos recientemente en el campo de los estudios migratorios por su presencia en regiones altamente centralizadas. El objetivo es analizar esta modalidad migratoria de los estudiantes de recién ingreso que cambiaron su residencia para iniciar sus estudios en la Universidad Veracruzana, en México. Empleando la teoría de Bourdieu y una metodología mixta, identificamos dos grupos de estudiantes según el capital cultural que poseen, el cual conforma trayectorias escolares y migratorias, y define el valor de los estudios universitarios.
TYUMEN “STALINKAS” AND THEIR INHABITANTS IN SOVIET AND POST-SOVIET EVERYDAY LIFE
Authors: SKIPINA Irina V. , Nemkov Andrey N.
Published: February 2021

This article studies a topical problem: the history of Tyumen “Stalinkas” in the 1930s-1950s and the everyday urban life of their inhabitants. The authors aim to show the process of pre- and post-war construction of residential buildings to provide apartments for Tyumen residents. Housing is considered as a necessary component of human activity.
The object of the study is an architectural ensemble of pre- and post-war Tyumen, which reflected the realities of the 1930-1950s. It was a time when slogans of equality were proclaimed, the authorities said that they would provide the same opportunities for life and self-realization for all Soviet citizens. However, the houses in the center of the city with spacious apartments were built for the Soviet elite, and small apartments of poor quality on the outskirts of the city — for workers. Housing for workers was located far from educational, leisure, and retail outlets.
Using the new documentary data, introduced for the first time into academic circulation, and taking into account a comprehensive approach to the study of the topic, the authors show the impact of housing development on urban daily life. “Stalinkas” are considered a legacy of the era of the cult of personality, which allows studying people’s everyday life, taking into account their social stratification based on their life, housing, everyday practices, and opportunities to participate in urban life.
The results show that “Stalinkas” are not only our past, but also our present, they are a clear proof of the construction of a bright future, which has proven to be unattainable, and their construction stopped shortly after Stalin’s death. Further study of urban ordinariness and everyday practices of citizens will bring us closer to understanding the phenomenon of the “Soviet” as an essential part of Russian identity.
INTERLANGUAGE TRANSFORMATIONS IN THE TRANSLATION FROM RUSSIAN INTO CHINESE OF G. SH. YAKHINA’S NOVEL “ZULEIKHA OPENS HER EYES”
Authors: ANDREEVA Iana Ye. , LABUNETS Natalia V.
Published: February 2021

This article deals with the lexical and grammatical transformations in the translation of G. Sh. Yakhina’s novel “Zuleikha Opens Her Eyes” into Chinese. Currently, the theoretical and practical issues of translation in the aspect of the Russian-Chinese language pair remain relevant. At the same time, the problems of translation equivalence and adequacy are getting more recognition.
This study aims to identify the specifics of interlingual transformations of Russian-Chinese translation based on a comparative analysis of the novel by G. Sh. Yakhina “Zuleikha Opens Her Eyes” (2015) and its Chinese translation (2017). It is the first such study of the presented literary text in terms of comparative-comparative linguistics. To comprehend the interlanguage transformations performed by the translator in the process of translation, the authors have used a comparative analysis of the texts in the source language and the translation.
The significance of the differences in the grammatical structure of the Russian and Chinese languages explains the particular interest towards the study of the translation of a work of fiction. At the lexical level, the authors examine the specifics of the transmission of the nationally-marked corpus of the Tatar vocabulary into Chinese, which acquires special significance in the representation of the ethnocultural component of a literary text. In addition, the features of lexical transformations during translation are revealed through an appeal to the ideological vocabulary of the Soviet period. At the grammatical level, the authors analyze the morphological and syntactic transformations, as well as the transmission of verb forms.
As a result of the study, the reasons for lexical, morphological and syntactycal translation transformations were established, and interlanguage barriers that reduce the equivalence of translation were identified.
Targeting Viral RNA-Dependent RNA Polymerases as an Antiviral Therapy
Authors: Miranda Daniel , Sanchez David Jesse
Published: February 2021

Progressive globalization of our society brings not only worldwide integration,
it also increases and promotes our exposure to new viral pathogens with evident impacts
on our global health. Especially with the emergence of SARS-CoV-2, our biomedical research
infrastructure has never been more compelled to rapidly develop antiviral regimens
that demonstrate improved efficacy against these pathogens. Here, we showcase 3 poignant
antivirals against the lucrative target, RNA-dependent RNA polymerase (RdRP) of
RNA viruses – a timely and relevant topic given the present efforts against COVID-19.
While effective drug designs against RdRP are important, their benefit and potential as a
standard of care truly relies on them standing out in well-designed clinical trials.
Docking Investigation on Bis (Nitro Indazolyl) Methanes; Synthesis and
Antimicrobial Activity Towards Breast Cancer Applications
Authors: Jagadeesan S. , Karpagam S.
Published: February 2021

:

Bismuth (III) nitrate pentahydrate (BN) was found to be a mild and efficient catalyst for the electrophilic condensation of 5-nitroindazole with a wide range of aldehydes to obtain Bis (5-nitro indazolyl) methanes 3 (a-h) at ambient
temperature. This was structurally confirmed from FTIR, NMR, and HR-MS technique. Molecular docking studies of all
compounds was carried out using breast cancer-causing human estrogen receptor (ER) from Molegro Virtual Docker software. Hydroxy Bis (nitro indazolyl) methanes (3b) were shown better binding affinities and the score obtained was -150.146
Kcal/mol compared with Tamoxifen drug. The major H-bond interactions were observed with the compound 3f and the
value was -5.679. The antimicrobial activity results revealed that compounds 3b and 3d showed promising activity against
bacteria Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, and Pseudomonas aeruginosa and maximum inhibition against Aspergillus niger and Aspergillus flavus. Methoxy derivatives of Bis (nitro indazolyl methanes) (3e) have
shown better antioxidant activity and low MIC (6.25 µg/ml) observed for the compounds 3a and 3b. The synthesized compounds have a very promising starting point for the development and improvement of anti-breast cancer drugs.
New Genetic Polymorphisms as an Epidemiological Factor of Arterial
Hypertension in Patients with Hyposodical Diet
Authors: López-Toledo Sabina , Ramírez-García Sergio A. , Cabrera-Pivaral Carlos E. , Flores-Alvarado Luis Javier , Ruiz Dalia Madrigal , Aguilar Aldrete María E. , Parada-Luna Felipe
Published: February 2021

Hypertension is a major public health problem, affecting more than a quarter of the world's population that causes serious cardiovascular problems. In recent years, different polymorphisms have been studied and helped to identify some candidate genes and hereditary syndromes associated to the molecular mechanisms involved in the development of hypertension. Therefore, it is important to identify these molecular mechanisms. This review exposes all the genes and polymorphisms that increase or decrease the risk of hypertension in different populations that are related to the renin angiotensin aldosterone system, G protein, salt excretion, aldosterone synthesis, lipid metabolism, mechanism of insulin resistance, vitamin metabolism, purines and sodium reabsorption. This document can be a useful tool in clinical practice, in addition to serving as a support for future research on this topic.
Highlighting Exosomes’ Function in Cardiovascular Diseases
Authors: Laksono Sidhi , Setianto Budhi , Prawara Ananta Siddhi , Dwiputra Bambang
Published: February 2021

:

Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in
the cell to cell communication. The cargos and surface protein of exosomes have been known to affect
the cardiovascular system both positively and negatively in chronic heart failure, ischemic
heart disease, and atherosclerosis. There have been several exosomes that emerged as potential diagnostic
and prognostic markers in cardiovascular patients. However, the conditions affecting the
patients and the method of isolation should be considered to create a standardized normal value of
the exosomes and the components. CPC-derived exosomes, ADSCs-derived exosomes, and telocyte-
derived exosomes have been proven to be capable of acting as a therapeutic agent in myocardial
infarction models. Exosomes have the potential to become a diagnostic marker, prognostic
marker, and therapeutic agent in cardiovascular diseases.
The Clinical Difference between Gabapentin and Pregabalin: Data from a Pilot Comparative Trial
Authors: Gammoh Omar , Al-Smadi Ahmed , Shawagfeh Mohammad Q. , Abadi Thani , Kasawneh Jawad , Malkawi Sukaina , Zein Sima
Published: February 2021

Background:

Similar anticonvulsants, such as gabapentin and pregabalin are recommended
in neuropathic pain management, however little is known about their clinical differences
in cases of low back pain. This paper aims to highlight some of the possible clinical differences between
gabapentin and pregabalin in low back pain.

Methods:

Patients with moderate to severe low back pain were recruited. Eligible patients were randomised
to receive either pregabalin (300 mg/day)or gabapentin (800 mg/day) for six weeks.

:

The primary outcome measure was pain intensity according to the Visual Analogue Score (VAS) at
baseline and at six weeks. The secondary outcome measures were: anxiety, insomnia, fatigue and
the self-rated (GCI), measured at baseline, second, fourth, and the sixth week.

Results:

A total of 64 patients, pregabalin group (n=28), gabapentin group (n=36) completed the
study. While pregabalin group showed a significantly lower pain score (p=0.039). The gabapentin
group showed significant improvement in anxiety (p=0.001), insomnia (p=0.001), general fatigue
(p=0.009), physical fatigue (p=0.001), reduce activity (p=0.001), and mental fatigue (p=0.014)
higher than that of pregabalin. No difference in (GCI) was seen at six weeks.

Conclusion:

This is the first trial aimed at comparing gabapentin with pregabalin in NLBP. Although
the results are preliminary, in our pilot study pregabalin was found to be superior in pain reduction,
gabapentin demonstrated better effect on anxiety, insomnia and fatigue symptoms. The results
are preliminary and studies with a larger sample size are still required.
Dara McAnulty. Diary of a Young Naturalist
Authors: Fleming Hannah
Published: February 2021

On the 20th August in 2018, 15-year-old Greta Thunberg sat for the first time outside the Swedish parliament demanding action be taken to tackle the climate crisis. The day before that, 14-year-old Dara McAnulty was walking through Tollymore forest when he came across ‘something discarded but utterly beautiful: a nest’ (118). He describes in his diary how he carried the nest with him, marvelling at the intricacy of the craftsmanship, before reluctantly setting it back down on the forest floor to provide shelter and the possibility of food for a nearby garden cross spider. This entry by McAnulty—a conservationist and environmental activist from Nothern Ireland—appears just over half-way through the book. The first and last diary entries are exactly one year apart, marking the end of Winter and the beginning of Spring, and in McAnulty’s mind, the midway point separating his late childhood from his adulthood.
A Cognitive-Semantic Study of Conceptual Metaphors in English News Reports
Authors: Jawad Hoshang Farooq , Noori Aram Kamil
Published: February 2021

This study explores how the development of the conceptual metaphor theory opened new horizons into the way language can be manipulated in the portrayal of the world and our immediate and distant environment of which news, including political news are part. Moreover, political news is the most pervasive type we continually come into contact in our daily communication.  Conceptual metaphor is a relation between two conceptual domains, namely, source domain which is concrete, and target domain which is abstract. For example, ARGUMENT IS WAR. We conceptualize and understand "ARGUMENT", the target domain, in terms of "WAR", and the source domain via a process called "mapping". The goal of the study is to carry out a cognitive analysis of conceptual metaphors used in political news reports and how reports of the two newspapers construe political issues reflected in their reports. Accordingly, the study aims to provide answers to such questions as:  How common are conceptual metaphors in English news reports of the online political register?  What types of conceptual metaphors are used in news reports in English newspapers?  How conceptual metaphors are experimentally based to human beings' life experiences? Based upon these research questions, it is hypothesized that Conceptual metaphors are argued to be as common in the news reports of the political register as they are in daily conversational language. Some types of conceptual metaphors are argued to be more common than others in the register in question. Moreover, all the conceptual metaphors are argued to have experiential bases which are related to our life experiences.

Index Terms— conceptual metaphor, source domain, target domain, invariance principle, news reports.
Monitoring of Sitting Postures With Sensor Networks in Controlled and Free-living Environments: Systematic Review
Authors: Kappattanavar Arpita Mallikarjuna , Steckhan Nico , Sachs Jan Philipp , Freitas da Cruz Harry , Böttinger Erwin , Arnrich Bert
Published: February 2021

Background

A majority of employees in the industrial world spend most of their working time in a seated position. Monitoring sitting postures can provide insights into the underlying causes of occupational discomforts such as low back pain.

Objective

This study focuses on the technologies and algorithms used to classify sitting postures on a chair with respect to spine and limb movements.

Methods

A total of three electronic literature databases were surveyed to identify studies classifying sitting postures in adults. Quality appraisal was performed to extract critical details and assess biases in the shortlisted papers.

Results

A total of 14 papers were shortlisted from 952 papers obtained after a systematic search. The majority of the studies used pressure sensors to measure sitting postures, whereas neural networks were the most frequently used approaches for classification tasks in this context. Only 2 studies were performed in a free-living environment. Most studies presented ethical and methodological shortcomings. Moreover, the findings indicate that the strategic placement of sensors can lead to better performance and lower costs.

Conclusions

The included studies differed in various aspects of design and analysis. The majority of studies were rated as medium quality according to our assessment. Our study suggests that future work for posture classification can benefit from using inertial measurement unit sensors, since they make it possible to differentiate among spine movements and similar postures, considering transitional movements between postures, and using three-dimensional cameras to annotate the data for ground truth. Finally, comparing such studies is challenging, as there are no standard definitions of sitting postures that could be used for classification. In addition, this study identifies five basic sitting postures along with different combinations of limb and spine movements to help guide future research efforts.
A Uniquely Targeted, Mobile App-Based HIV Prevention Intervention for Young Transgender Women: Adaptation and Usability Study
Authors: Kuhns Lisa M , Hereth Jane , Garofalo Robert , Hidalgo Marco , Johnson Amy K , Schnall Rebecca , Reisner Sari L , Belzer Marvin , Mimiaga Matthew J
Published: February 2021

Background

Young transgender women (YTW) are a key population for HIV-related risk reduction, yet very few interventions have been developed to meet their needs. Mobile health interventions with the potential for both efficacy and wide reach are a promising strategy to reduce HIV risk among YTW.

Objective

This study aims to adapt an efficacious group-based intervention to a mobile app, Project LifeSkills, to reduce HIV risk among YTW, and to test its acceptability and usability.

Methods

The group-based intervention was adapted to a mobile app, LifeSkills Mobile, with input from an expert advisory group and feedback from YTW collected during user-centered design sessions. A beta version of the app was then tested in a usability evaluation using a think-aloud protocol with debriefing interviews, recordings of screen activity, and assessments of usability via the Post-Study System Usability Questionnaire (PSSUQ) and the Health Information Technology Usability Evaluation Scale (Health-ITUES).

Results

YTW (n=8; age: mean 24 years, SD 3 years; racial or ethnic minority: 7/8, 88%) provided feedback on the app prototype in design sessions and then tested a beta version of the app in a usability trial (n=10; age: mean 24 years, SD 3 years; racial or ethnic minority: 8/10, 80%). Both usability ratings (Health-ITUES: mean 4.59, SD 0.86; scale range: 1-5) and ratings for satisfaction and accessibility (PSSUQ: mean 4.64, SD 0.90; scale range 1-5) were in the good to excellent range. No functional bugs were identified, and all mobile activities were deployed as expected. Participant feedback from the usability interviews indicated very good salience of the intervention content among the focal population. Participants’ suggestions to further increase app engagement included adding animation, adding audio, and reducing the amount text.

Conclusions

We conclude that the LifeSkills Mobile app is a highly usable and engaging mobile app for HIV prevention among YTW.
Moderated Online Social Therapy for Young People With Active Suicidal Ideation: Qualitative Study
Authors: Bailey Eleanor , Robinson Jo , Alvarez-Jimenez Mario , Nedeljkovic Maja , Valentine Lee , Bendall Sarah , D'Alfonso Simon , Gilbertson Tamsyn , McKechnie Ben , Rice Simon
Published: February 2021

Background

Web-based interventions are a promising approach to support youth at risk of suicide, and those incorporating peer-to-peer social networking may have the added potential to target interpersonal states of perceived burdensomeness and thwarted belongingness. Owing to feasibility and safety concerns, including fear of contagion, this had not been tested until recently. In 2018, we conducted a pilot evaluation to test the feasibility, safety, and acceptability of a Moderated Online Social Therapy intervention, called Affinity, with a sample of young people with active suicidal ideation.

Objective

The aim of this study is to report qualitative data collected from study participants regarding their experience of the web-based social network and the consequent safety features.

Methods

Affinity is a closed website incorporating 3 key components: therapeutic content delivered via comics, peer-to-peer social networking, and moderation by peers and clinicians. Semistructured interviews were conducted with 17 young people who participated in the pilot study after 8 weeks of exposure to the intervention. Interview data from 2 young people who did not use Affinity were excluded from the analysis. The interviews were analyzed using thematic analysis, with the frequency of responses characterized using the consensual qualitative research method. The results are reported in accordance with the Consolidated Criteria for Reporting Qualitative Research checklist.

Results

A total of 4 overarching themes were identified: a safe and supportive environment, the importance of mutual experiences, difficulty engaging and connecting, and the pros and cons of banning discussions about suicide. Interestingly, although Affinity was perceived to be safe and free of judgment, concerns about negative evaluation and triggering others were significant barriers to posting on the social network. Participants generally supported the banning of conversations about suicide, although for some this was perceived to reinforce stigma or was associated with frustration and distress.

Conclusions

The results not only support the safety and potential therapeutic benefit of the social networking aspect of Affinity but also highlight several implementation challenges. There is a need to carefully balance the need for stringent safety and design features while ensuring that the potential for therapeutic benefit is maximized.
Barriers to and Facilitators of User Engagement With Digital Mental Health Interventions: Systematic Review
Authors: Borghouts Judith , Eikey Elizabeth , Mark Gloria , De Leon Cinthia , Schueller Stephen M , Schneider Margaret , Stadnick Nicole , Zheng Kai , Mukamel Dana , Sorkin Dara H
Published: February 2021

Background

Digital mental health interventions (DMHIs), which deliver mental health support via technologies such as mobile apps, can increase access to mental health support, and many studies have demonstrated their effectiveness in improving symptoms. However, user engagement varies, with regard to a user’s uptake and sustained interactions with these interventions.

Objective

This systematic review aims to identify common barriers and facilitators that influence user engagement with DMHIs.

Methods

A systematic search was conducted in the SCOPUS, PubMed, PsycINFO, Web of Science, and Cochrane Library databases. Empirical studies that report qualitative and/or quantitative data were included.

Results

A total of 208 articles met the inclusion criteria. The included articles used a variety of methodologies, including interviews, surveys, focus groups, workshops, field studies, and analysis of user reviews. Factors extracted for coding were related to the end user, the program or content offered by the intervention, and the technology and implementation environment. Common barriers included severe mental health issues that hampered engagement, technical issues, and a lack of personalization. Common facilitators were social connectedness facilitated by the intervention, increased insight into health, and a feeling of being in control of one’s own health.

Conclusions

Although previous research suggests that DMHIs can be useful in supporting mental health, contextual factors are important determinants of whether users actually engage with these interventions. The factors identified in this review can provide guidance when evaluating DMHIs to help explain and understand user engagement and can inform the design and development of new digital interventions.
Bed Sensor Technology for Objective Sleep Monitoring Within the Clinical Rehabilitation Setting: Observational Feasibility Study (Preprint)
Authors: Hendriks Maartje M S , van Lotringen Jaap H , Vos-van der Hulst Marije , Keijsers Noël L W
Published: February 2021

BACKGROUND

Since adequate sleep is essential for optimal inpatient rehabilitation, there is an increased interest in sleep assessment. Unobtrusive, contactless, portable bed sensors show great potential for objective sleep analysis.

OBJECTIVE

The aim of this study was to investigate the feasibility of a bed sensor for continuous sleep monitoring overnight in a clinical rehabilitation center.

METHODS

Patients with incomplete spinal cord injury (iSCI) or stroke were monitored overnight for a 1-week period during their in-hospital rehabilitation using the Emfit QS bed sensor. Feasibility was examined based on missing measurement nights, coverage percentages, and missing periods of heart rate (HR) and respiratory rate (RR). Furthermore, descriptive data of sleep-related parameters (nocturnal HR, RR, movement activity, and bed exits) were reported.

RESULTS

In total, 24 participants (12 iSCI, 12 stroke) were measured. Of the 132 nights, 5 (3.8%) missed sensor data due to Wi-Fi (2), slipping away (1), or unknown (2) errors. Coverage percentages of HR and RR were 97% and 93% for iSCI and 99% and 97% for stroke participants. Two-thirds of the missing HR and RR periods had a short duration of ≤120 seconds. Patients with an iSCI had an average nocturnal HR of 72 (SD 13) beats per minute (bpm), RR of 16 (SD 3) cycles per minute (cpm), and movement activity of 239 (SD 116) activity points, and had 86 reported and 84 recorded bed exits. Patients with a stroke had an average nocturnal HR of 61 (SD 8) bpm, RR of 15 (SD 1) cpm, and movement activity of 136 (SD 49) activity points, and 42 reported and 57 recorded bed exits. Patients with an iSCI had significantly higher nocturnal HR (t18=−2.1, P=.04) and movement activity (t18=−1.2, P=.02) compared to stroke patients. Furthermore, there was a difference between self-reported and recorded bed exits per night in 26% and 38% of the nights for iSCI and stroke patients, respectively.

CONCLUSIONS

It is feasible to implement the bed sensor for continuous sleep monitoring in the clinical rehabilitation setting. This study provides a good foundation for further bed sensor development addressing sleep types and sleep disorders to optimize care for rehabilitants.
A Social Network Analysis of Pro-maskers and Anti-maskers on Twitter during the COVID-19 Pandemic (Preprint)
Authors: Ahmed Wasim , Khan Laeeq , Malik Aqdas
Published: February 2021

BACKGROUND

Online debates surrounding face masks as a precautionary measure against COVID-19 pandemic have been raging on social media platforms like Twitter. Users against or in favor of masks have be vocal in sharing their opinions about the masks wearing, practices, and consequences. Through a social network analysis (SNA), we unearth the important contributors to the debate on Twitter surrounding pro and anti-masks.

OBJECTIVE

The aim of this study is to develop an understanding of the content and influencers on Twitter related to anti-mask and pro-mask debates.

METHODS

In this study 18,000 tweets related to keywords that were either pro mask and anti-mask from 12th December 2020, to 18th December 2020, and 18,000 tweets from 9th of December to the 18th of December 2020. The two datasets were analysed using social network analysis in Gephi, meanwhile NodeXL was used to produce network metrics and identify the key users, websites, and content within the data.

RESULTS

Discussions for both the cases revolved around prominent political figures and their supporters. The anti-mask discussions contained frequent mentions to Donald Trump’s Twitter account which made the account the most influential within the anti-mask network. On the contrary, for tweets that were pro-mask the most influential user was Joe Biden. Our network visualization further identified several clusters within the network and found that influential accounts appeared with sizeable clusters. Keywords used by Twitter users for pro-masking revolved around words that were in support of masking. Whereas tweets related to anti-masks appeared to be broader and included words related to news stories of popular figures not wearing face masks. For pro-mask discussions, popular websites also appeared to support the idea of wearing masks whereas the anti-mask data contained references to news stories of popular figures not wearing masks and of news stories related to a study which noted not wearing a mask was safer than wearing a used mask.

CONCLUSIONS

The current study highlights how discussions around pro-mask and anti-mask revolved around the key political figures. Our results are likely to be of interest to public health authorities involved in encouraging the public to wear masks. The study highlighted key users that could be targeted for information dissemination about face masks. The study further provided insight into narratives and online resources shared through pro-masking and anti-masking accounts.
IN SILICO DESIGN OF QUINOXALINE BEARING THIAZOLIDINONE DERIVATIVES AS PPARγ AGONIST IN DIABETES MELLITUS
Authors: T POORNIMA , PT MANJU , E ANJANA
Published: February 2021

Objective: Diabetes mellitus is a set of metabolic disease in which there is increased blood sugar level over a long period. The objective of the study is in silico design of quinoxaline bearing thiazolidinone derivatives as peroxisome proliferator-activated receptor gamma (PPARγagonist in diabetes mellitus.

Methods: In silico design of proposed derivatives was conducted by ACD Lab ChemSketch 12.0 and derivatives obeying Lipinski’s rule of five were selected for docking studies. Docking was carried out using AutoDock Vina software.

Results: Molinspiration results revealed that the designed derivatives had physical and chemical properties meant for an orally available drug. Based on the docking results derivatives, QNT1 and QNT2 exhibited high docking score which indicates that these derivatives possess high-affinity and high polar interaction toward protein 1PRG (ligand-binding domain of human peroxisome proliferator-activated receptor gamma).

Conclusion: The designed quinoxaline bearing thiazolidinone derivatives were found to possess good binding affinity and good interaction in the binding pocket of target 1PRG, so these derivatives are expected to exhibit good antidiabetic property with minimal side effects.
BIOSYNTHESIZED SILVER NANOPARTICLES USING CATHARANTHUS ROSEUS AND THEIR ANTIBACTERIAL EFFICACY IN SYNERGY WITH ANTIBIOTICS; A FUTURE ADVANCEMENT IN NANOMEDICINE
Authors: GUPTA MONIKA
Published: February 2021

Objective: This research work develops an approach to synthesize silver nanoparticles (AgNPs) by reduction of leaf extract of Catharanthus roseus plant. This study produces synthesized nanoparticles that have process-controlled attributes which make their antibiotic action highly efficient. These attributes include smaller size, proper morphology, uniform dispersion, metal ion content, and formation of functional groups. By optimizing the reduction process parameters, AgNPs gain the desired properties.

 Methods: The biosynthesis of AgNPs process was performed using reaction of 10% (w/v) C. roseus leaf extract with AgNO3. The optimum conditions and concentration used for synthesis of nanoparticles were: 1 mM AgNO3, pH 5, and temperature 80°C with an incubation time of 72 h. All the above parameters were analyzed by ultraviolet-visible spectrophotometer with the surface plasmon resonance peak obtained at 440 nm.

Results: Various characterization techniques were performed, namely, scanning electron microscopy, energy-dispersive X-ray, transmission electron microscopy, photoluminescence study, X-ray diffraction spectroscopy, Fourier transform infrared, dynamic light scattering, and atomic force microscopy. The results obtained from characterization confirmed the spherical morphology of the nanoparticles with size between 50 and 87 nm. In the current investigation, the antimicrobial activity of biosynthesized AgNPs was also determined using minimum inhibitory concentration and zone of inhibition methods against six different bacteria at different doses of AgNPs (100, 150, and 200 μg/ml) alone and also in combination with antibiotic-streptomycin.

Conclusion: The results revealed that high concentration of AgNPs inhibits the bacterial growth. Furthermore, AgNPs revealed much stronger antibacterial action in synergy with streptomycin against antibiotic-resistant bacteria.
STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION OF FIMASARTAN BY REVERSE-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY IN BULK AND PHARMACEUTICAL DOSAGE FORM
Authors: A SRUTHI , PRASAD PANIGRAHY UTTAM
Published: February 2021

Objective: A rapid, sensitive and specific reverse phase High performance liquid Chromatography (RP-HPLC) method was developed for the estimation of Fimasartan in bulk and pharmaceutical dosage form.

Method: The RP-HPLC analysis was performed isocratically on a Primacel C18 column (150 mm × 4.6 mm internal diameter, 5 μm particle size) using mobile phase of composition Acetonitrile and 0.1% orthophosphoric Acid in 80:20, v/v proportions with a flow rate of 0.8 ml/min.

Results: The analyte was monitered with UV-detector at 265 nm. In the developed method Fimasartan elutes at a typical retention time of 2.4 min. The proposed method is having linearity in the concentration ranging from 5-30 μg/ml of Fimasartan.

Conclusion: : The method was statistically validated and had been applied to analysis of the drug in bulk and pharmaceutical dosage form.
EXTENSIVE EPIDEMIOLOGICAL STUDY OF TRAUMATIC PNEUMOTHORAX IN SAUDI ARABIA’S POPULATION
Authors: ALRASHIDI NASSER
Published: February 2021

Objectives: Traumatic pneumothorax is one of the causes of trauma mortality and morbidity. It is a problem for developing countries as many accidents can be avoided and there are few epidemiological data to support programs injury prevention. The main objective of the current study was to determine demographic characteristics, patterns, and severity of the injury, thoracic, and extra-thoracic related injuries in a Level 1 trauma center, Riyadh, Saudi Arabia (SA).

Methods: This retrospective observational study used the King Abdulaziz Medical City Trauma Center’s trauma registry to review the data of traumatic pneumothorax patients admitted to the hospital from January 2001 to December 2018. Demographic characteristics, admission date and time, type and mechanism of injury, involved body area, and severity rates were analyzed.

Results: A total of 708 patients of whom 92.3% were males. Blunt trauma (75.8%) is the most common cause of injury. Motor Vehicle Accidents (MVA) were the most common cause (57%) of traumatic pneumothorax. Rib fractures (36.5%), lung contusions (31.5%), and hemothorax (23.5%) were the most common clinical forms of chest injury associated with traumatic pneumothorax. On the other hand, the head injury (34.8%) was the most common extra thoracic part associated. The mean Injury Severity Score in the current study was found to be 20.1.

Conclusion: This study showed the trends of traumatic pneumothorax injuries in a Level 1 trauma center, Riyadh, SA, showing MVA are the leading cause of traumatic pneumothorax in our region. These demographic data will be crucial for local health-care systems to be optimally resourced.
STEVENS-JOHNSON SYNDROME DUE TO ADVERSE DRUG REACTIONS: A CASE SERIES
Authors: ANSARI ZAFAR MASOOD , SRIVASTAVA BHAVANA , ROHATGI ARUNIMA
Published: February 2021

Stevens-Johnson syndrome (SJS) is a rare, serious disorder affecting skin and mucous membranes. It is one of the few serious dermatological adverse effects of drugs encountered in clinical practice which is characterized by blisters and rash on skin, mucous membranes, swelling over face and lips, and hyperpigmentation. After that, the outer layer of affected skin becomes dead, sheds, and starts to heal after several days of inflicting injury. Here, we present a case series of ofloxacin and chloroquine induced SJS after the consent given by patients. First case is a 62 years old male received Ofloxacin and second patient is a 40 years old male received chloroquine. Both patients experienced a severe skin reaction which was diagnosed as SJS. The above-mentioned medications will be implicated in cases of SJS. We should prescribe these medications with extreme caution.
PATTERN OF SUSPECTED ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL – A CROSS-SECTIONAL STUDY
Authors: KORUTHARA MOHANAN LIMA , HARICHANDRAN DHANYA THIROOKARAN , KB SANALKUMAR
Published: February 2021

Objective: The objective of the study was to study the pattern of suspected adverse drug reactions (ADRs) in a tertiary care hospital.

Methods: This is a cross-sectional study conducted in the Department of Pharmacology of a Tertiary Care Teaching Hospital, Kerala. As part of pharmacovigilance activities, the ADRs were collected in Central Drug Standard Control Organization Suspected ADR reporting form from various departments during a period of 3 months and recorded in Pharmacovigilance register maintained by the pharmacology department. As part of our study, we collected the details such as patient’s initials, age, gender, reporting department of hospital, description of the ADR, duration of the reaction, name of suspected ADRs, and outcome from the Pharmacovigilance register. Descriptive statistics will be used for data analysis by statistical package for the social science for windows 16.

Results: Two hundred and twenty-two ADR from 141 patients obtained during a period of 3 months. The maximum ADR reports were in age group more than 50 years of age. The skin and appendages were most affected followed by gastrointestinal tract. Antineoplastic drugs accounted for 59.7% of drug class suspected for ADRs followed by use of more than one drug (14.1%). Among antineoplastic drugs, cyclophosphamide and carboplatin accounted for majority causes of ADR. The antibiotics accounted for 12.7% of all drugs. Among the antibiotics penicillin and cephalosporins caused most of the ADRs.

Conclusion: The maximum number of ADR reported in our study was with the use of antineoplastic drugs and most common ADR reported was alopecia.
Family Education and Child Socialization in Observant Muslim Community of the Republic of Tatarstan
Authors: Guzelbaeva G. Yu.
Published: February 2021

The paper is devoted to the study of practices of Islamic education in right-wing observant Muslim families, namely of their homeschooling. The paper focuses on (1) how Muslims and their children cope with difficulties in observing Islamic precepts and performing the ritual side of religion in public schools, (2) what aspects of standard secular education and school environment prevent children from adopting Islamic worldview, (3) what educational practices are used by parents for religious education of children. As observant respondents affirm, homeschooling provides opportunities for maximum immersion of a child in the environment of a religious community. An informal approach to educational process and an individual schedule frees up some time for learning the basics of Islam as well as allows children to spend more time with parents and the external religious environment. According to advocates of homeschooling, this ensures a smooth and non-violent adoption of religious values and better acquisition of moral norms. However, the paper concentrates also on the opinion of Muslims, who do not support homeschooling. Namely these respondents argue for desirable control over religious homeschooling, which should be provided by state institutions as well as by registered religious organizations.
“The Mukri Kurds” by O. L. Vilchevsky: What and Why Has Been Deleted Before Publication?
Authors: Pobedonostseva-Kaya A. O.
Published: February 2021

The article deals with the problem of political inﬂuence on scholarship. It analyses the existing versions of an ethnographic essay by Oleg Vilchevsky, a prominent Soviet Orientalist. Alongside a published version the ethnographic essay “The Mukri Kurds” — an author’s typescript, “Mukri Kurdistan,” has been found in the Scientiﬁc Archive of Peter the Great Museum of Anthropology and Ethnography (the Kunstkamera) of the Russian Academy of Sciences. The ﬁrst materials for this essay were collected by Vilchevsky during his journey to Iran in 1942 as he prepared a military-political description of the Kurdish regions. Before publication, the state-controlled structures removed or made the author remove from the essay a number of important thematic blocks, e. g., on interconfessional relations in Mukri Kurdistan of Iran (focusing on Mahabad), descriptions of various meetings Vilchevsky held with Kurdish activists. The paper analyses the content of this scholarly study and the problems related to the publication of the essay in the context of Vilchevsky’s participation as a Soviet military officer in the implementation of the Soviet Middle Eastern policies in 1942–1954. The author of the essay “The Mukri Kurds” apparently strived to maintain scholarly neutrality yet the facts and argumentation contained in the different variants of this study were consistently reviewed and added or omitted depending on the existing political situation. The paper raises the question about the subjectivity or autonomy of a scholar serving a government — something effectively dismissed and neglected in the work of Edward Said on the relationship between politics and scholarship in the ﬁeld of Middle Eastern studies.
Exact and approximate continuous-variable gate decompositions
Authors: Kalajdzievski Timjan , Quesada Nicolás
Published: February 2021

We gather and examine in detail gate decomposition techniques for continuous-variable quantum computers and also introduce some new techniques which expand on these methods. Both exact and approximate decomposition methods are studied and gate counts are compared for some common operations. While each having distinct advantages, we find that exact decompositions have lower gate counts whereas approximate techniques can cover decompositions for all continuous-variable operations but require significant circuit depth for a modest precision.
Bendable UHF RFID tag antenna for retail garments using non-uniform meandered lines
Authors: Kumar Manoj , sharma ashwani , Zuazola Ignacio J. Garcia
Published: February 2021

A bendable UHF RFID tag antenna using non-uniform meandered lines for
retail garments in the textile industry is presented. Based on an
earlier UHF RFID tag antenna using nonuniform meandered lines, the
proposed tag is fully bendable and aimed to be embedded in retail
garments for long-life cycles. As a result, a relatively low cost, wide
band, compactness and good conjugate matching with good dipole-like read
range is presented. Results showed an antenna with a wide bandwidth of
900MHz and a long read range of 10.1m making the UHF RFID tag antenna
using non-uniform meandered lines a potential candidate for retail
garments in bendable applications of the textile industry. Simulations
are corroborated by measurements and are in fairly agreement.
Research on construction engineering safety Risk Control based on IAHP-TOPSIS
Authors: DU Minggang , HAN Tongyin
Published: February 2021

Based on the improved analytic hierarchy process (IAHP) and TOPSIS
method to build the construction project safety evaluation index system
used to evaluate the safety management of construction projects in the
construction stage, so as to control the safety risk of the project,
prevent the occurrence of safety accidents, and improve the level of
safety management. Through make a statistical analysis of the recent
safety accidents in construction projects in China, comprehensively
consider the four aspects of human, object, environment and management,
establish 12 evaluation indexes of construction project safety
management. Through improved analytic hierarchy process (AHP) to
determine evaluation index weights vector, combined with the ideal
solutions for sorting method, put forward a IAHP method and TOPSIS
method based on the safety evaluation model.The research results show
that the model can accurately show the deficiencies of the safety
management of the evaluation object, and directly reflect the safety
management level of the evaluation object. The research conclusion is
consistent with the actual situation of the project, which can provide
guidance for the improvement of safety redundancy and safety risk
control of construction engineering.