bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Phytochemical Characteristics of Walnut (Juglans regia) Leaves: Determination of Nutritional Value and Quantitative Content of Phenolic Compounds
Authors: Gaviley Olena , Pankova Svitlana , Poliakova Lydmila , Chorna Ganna
Published: September 2024

This study aimed to assess the nutritional value of walnut leaves (Juglans regia), investigate the content of major polyphenolic compounds in walnut leaves, and assess the potential of walnut leaves as a phytogenic supplement to poultry diets. The nutritional composition of dried ground walnut leaves (crude protein, crude fat, crude fiber, calcium, phosphorus, vitamin E, b-carotene) was assessed according to generally accepted methods. The quantitative content of individual groups of polyphenols, such as total phenols, hydroxycinnamic acids, flavonoids, and juglon, was determined spectrophotometrically. The content of the sum of tannins was determined by the titrimetric method. Walnut leaves contain a high content of b-carotene (295.0 μg/g) and natural antioxidant vitamin E (128.8 μg/g). The protein content was noted at the level of 12.5%, the fiber content - 12.86%. In a significant amount, calcium and phosphorus accumulated in walnut leaves - 2.04% and 0.23%, respectively. The content of the total hydroxycoric acids in terms of chlorogenic acid in walnut leaves was 24.3 mg/g, the total content of phenolic compounds in gallic acid equivalent was 14.4 mg/g, flavonoids in rutin equivalent was 20.2 mg/g, and juglone was 2.72 mg/g. The content of total tannins in walnut leaves was 124.5 mg/g. The high nutritional value of walnut leaves compared to alfalfa meal and the presence of a number of biologically active polyphenolic compounds in a significant amount give grounds to consider this phyto-raw material not only as a valuable feed component, but also as a source of natural antioxidants.
“Sandwich”-like keyed algorithm based on the “Streebog” hash function
Authors:   LLC “SFB Lab”, Kiryukhin Vitaly A. ,   JSC ",   InfoTeCS", Sergeev Andrey M. ,   LLC “SFB Lab”
Published: September 2024

We propose a keyed cryptographic algorithm based on the “Streebog” hash function. We do not make any structural changes to the hash function itself, but only introduce a special type of padding. As a result, the key appears on both sides of the message in so-called “sandwich” manner - hence the name Streebog-S for our construction. “Sandwich” properties make it possible to simplify defenses against side-channel attacks while maintaining their effectiveness. We prove that Streebog-S and other algorithms based on “Streebog”, HMAC-Streebog and Streebog-K, remain secure as pseudorandom functions (PRF) and message authentication codes (MAC) even when almost all internal states are leaked to the adversary. This leakage resistance requires additional properties from the underlying compression function, namely collision- and preimage-resistance.
Calculation of error-correcting pairs for an algebraicgeometric code
Authors:   Immanuel Kant Baltic Federal University, Kuninets Artem A. , Malygina Ekaterina S. ,   National Research University Higher School of Economics
Published: September 2024

For an arbitrary algebrogeometric code and its dual, error-correcting pairs are explicitly calculated. Such a pair consists of codes that are necessary for an efficient decoding algorithm for a given code. The type of pairs depends on the powers of the divisors, with the help of which both the source code and one of the codes included in the pair are constructed. For an algebraic geometric code CL(D, G) of length and associated with a functional field F/Fq of genus g, pairs correcting t = ⌊(n - deg( G) - g - 1)/2⌋ errors, under certain restrictions on the degrees of divisors involved in their construction, are pairs of codes (Cl(D,F),Cl(D,G + F)⊥) or (CL(D,F⊥),Cl(D,F - G)). Restrictions on the degrees of divisors of codes (CL(D,F), CL(D,G - F)) constituting a pair correcting t = ⌊(deg( G) - 3g + 1)/2⌋ errors for the dual code CL(D, G)⊥) Cases where one of the codes involved in constructing a pair belongs to class of MDS codes and the parameters under which this situation is possible are derived. In addition, possible bounds for the divisors involved in the construction of error-correcting pairs for the subfield subcodes CL(D,G)|fp and CL< are calculated /sub>(D, G)⊥)|Fp of the original algebrogeometric code and its dual, with the expansion degree m = 2 (Fq = Fp2).
Vulnerability To Disinformation In Older Age
Authors: Meini Cristina , Rosola Martina
Published: September 2024

Disinformation poses a significant challenge to contemporary society, as it has the potential to undermine the stability of democratic systems, put public health at risk, and undermine the credibility of science. We explore the question of whether certain groups of people are especially exposed to disinformation and, in particular, we focus on older people. We examine the purported impact of cognitive and linguistic factors, such as source amnesia and the need for consistency, the decline of pragmatic skills in recognizing intentions and decoding figurative language, as well as motivational factors like the need for affiliation. Taken together, these empirical data suggest that there may indeed be specific vulnerabilities associated with older age. This hypothesis calls for finding ways to protect a category of people who already suffer from numerous other vulnerabilities.
Experimental determination of creep coefficients for sintered flyash lightweight aggregate based concrete and verification with creep models
Authors:   Birla Institute of Technology & Sciences Pilani, Pilani & Group Manager at National Council for Cement & Building Materials, Ballabgarh, India, Singh Brijesh , Singh Shamsher Bahadur ,   Department of Civil Engineering, Birla Institute of Technology & Sciences Pilani, Pilani, India, Barai Sudhirkumar V. ,   Department of Civil Engineering, Birla Institute of Technology & Sciences Pilani, Pilani, India, Singh Abhishek ,   Dalmia Cement (Bharat) Limited, India, Ojha P N ,   National Council for Cement & Building Materials, Ballabgarh, India
Published: September 2024

The experimental creep coefficient has been determined for two concrete strengths of about 40 MPa and 60 MPa using sintered flyash lightweight aggregate and granite aggregate in creep rig with capacity of 1500kN as per ASTM C-512. The creep results indicate that despite both density and modulus of elasticity being on lower side for sintered flyash lightweight based concrete, the creep coefficient has been lower than that of normal weight concrete with granite aggregate for same strength level. The comparison of existing creep models has been carried out with experimental results for both normal and lightweight concrete considering parameters in models such as relative humidity level, concrete mix ingredients, aggregate properties, oven dry density, elastic modulus of both concrete types etc. considered in study. The creep coefficients have been obtained experimentally at loading age of 28-day and testing period of 365 days and has been compared with existing creep models such as B-3, B-4, ACI-209, EN:1992/FIB. For the similar compressive strength level, creep coefficient of structural grade lightweight concrete is found to be lower in comparison to creep coefficient of normal weight concrete as the internally stored water in porous aggregates keeps capillary pores almost saturated and leaves minimal chance for seepage to occur
La arqueología en articulación con los museos de la Región Pampeana argentina. Desafíos actuales y temas pendientes
Authors:   Universidad Nacional del Centro de la Provincia de Buenos Aires, Chaparro María Gabriela , Pupio María Alejandra ,   Universidad Nacional del Sur, Lanzelotti Sonia ,   Universidad de Buenos Aires, Caro Petersen Agueda ,   Comisión Nacional de Energía Atómica- Centro Atómico Bariloche, Molinengo María Belén ,   Universidad Nacional de Rosario, Arias Morales Cecilia ,   Universidad Nacional de Rosario, Rouco Rosana ,   Museo Histórico Regional "Marta Inés Martínez”, Salerno Virginia ,   Universidad de Buenos Aires
Published: September 2024

Los museos de la región pampeana argentina en los últimos años se han posicionado como espacios articuladores en el territorio y han comenzado a replantear sus exposiciones y narrativas museales, el trabajo con los públicos, sus prácticas educativas, de conservación y de investigación. En este escenario, desde la arqueología y la antropología se profundizaron los debates sobre la historia y el quehacer disciplinar en vínculo con los espacios museísticos. Además, un grupo de profesionales de estas disciplinas ha ocupado diferentes lugares y se ha articulado con estas instituciones. En este espacio presentamos cuatro experiencias de trabajo en museos y analizamos esta vinculación, las fortalezas, los desafíos actuales y los temas pendientes que requieren pronta resolución.
Marcadores biológicos de conducta suicida en paciente con enfermedad mental grave: revisión narrativa
Authors:   Universidad de Antioquia, Cárdenas-Urbano Rafael Santiago , Vera-Henao Sebastián ,   Universidad de Antioquia, García-Valencia Jenny ,   Universidad de Antioquia, López-Jaramillo Carlos ,   Universidad de Antioquia
Published: September 2024

Introducción: el suicidio es un problema de salud pública importante. Entre sus factores de riesgo se destacan las enfermedades mentales. En la búsqueda de la detección temprana de conductas suicidas, se han estudiado varios marcadores de predicción en población psiquiátrica. Objetivos: presentar una revisión narrativa acerca de marcadores biológicos relacionados con suicidio. Metodología: se realizó una búsqueda bibliográfica en las bases de datos PubMed, SCIELO, Science Direct y EMBASE, utilizando como términos: “enfermedad mental grave”, “trastorno afectivo bipolar”, “depresión grave”, “esquizofrenia”, “suicidio”, “marcadores”. Se tuvieron en cuenta estudios en español e inglés y fueron incluidos artículos disponibles hasta agosto del 2023, sin distinción en el diseño. Se excluyeron artículos relacionados con otras enfermedades mentales. Resultados: los marcadores biológicos que más se han estudiado en relación con conductas suicidas en enfermedad mental grave constituyen los sistemas de monoaminas y moléculas inflamatorias sistémicas. Los marcadores genéticos, principalmente en relación con la serotonina y con el eje hipotálamo-hipófisis-suprarrenal (HHS), también han cobrado importancia en los últimos años. Conclusiones: ha sido notable el estudio de marcadores biológicos en relación con la conducta suicida en población con enfermedad mental grave; sin embargo, hace falta investigación sobre otros mecanismos fisiopatológicos del suicidio.
Tropical grasses used in haylage production: An integrative review
Authors:   Universidade Federal do Piauí, de Almeida Duarte Ana Beatriz , Dias-Silva Tairon Pannunzio ,   Universidade Federal do Piauí, Correa-Viana Wesleyson Cristian ,   Universidade Federal do Piauí, Chaves-Gurgel Antonio Leandro ,   Universidade Federal do Piauí, de Araújo Marcos Jácome ,   Universidade Federal do Piauí, Rocha-Bezerra Leílson ,   Universidade Federal de Campina Grande, Rodrigues do-Nascimento Romilda ,   Universidade Federal de Campina Grande, Torreão-Marques Carlo Aldrovandi ,   Universidade Federal do Rio grande do Norte, Loiola-Edvan Ricardo ,   Universidade Federal do Piauí, Vinhas-Ítavo Luis Carlos ,   Universidade Federal de Mato Grosso do Sul, Chay-Canul Alfonso Juventino ,   Universidad Juárez Autónoma de Tabasco
Published: September 2024

Background: Haylage is a way of preserving forage with good nutritional value, consisting of the partial removal of water from the plant through the wilting technique. Objective: To identify the main tropical grasses used in haylage production, we developed an integrative review. Methods: Through the PVO mnemonic strategy, which consists of population (P): tropical forage grasses, variables (V): haylage production, and outcome (O): qualitative parameters, we raised the following question: “What are the main tropical forage grasses used in haylage production?” Papers were selected from three different databases: SCOPUS (Elsevier), Web of Science, and Science Direct. Results: The search identified 1,049 articles, but only 10 were considered suitable and included for data extraction. Among the grasses used, 50% were of Cynodon spp., 30% of Panicum maximum, 10% of Festuca rubr, 10% of Dactylis glomerata, and 10% of Trisetum flavescens. Conclusion: We conclude that the main forage grasses used in pre-dried silage production belong to the genera Cynodon spp. and Panicum spp., highlighting Tifton-85 grass and Tanzania grass, respectively.
Penyuaian Model Analisis Penyampulan Data: Bukti Empirikal daripada Institusi Wakaf
Authors: Md Razali Nurul Hidayah , Yakob Rubayah , Isa Zaidi , Bangaan Abdullah Mohd Hafizuddin Syah
Published: September 2024

Analisis Penyampulan Data (APD) ialah kaedah analisis bukan parametrik yang boleh menghitung skor kecekapan dengan mempertimbangkan input dan output. Model APD telah melalui beberapa semakan sejak awal diperkenalkan oleh Farrell pada tahun 1957. Model awal, yang dikenali sebagai Model CCR, telah diperkenalkan oleh Charnes, Cooper dan Rhodes pada tahun 1978. Ini diikuti oleh Model BCC, dibangunkan oleh Bankers, Charnes, dan Cooper pada tahun 1984. Dari masa ke masa, APD telah berkembang menjadi model yang lebih rumit yang dikenali sebagai APD Dinamik. Contohnya, Model TT, yang diasaskan oleh Tone dan Tsutsui pada tahun 2010. Penggunaan Model TT memfokuskan kepada pengiraan kecekapan yang mengambil kira kesinambungan aktiviti bawaan atau peralihan. Oleh itu, objektif kajian ini adalah untuk menentukan model APD yang paling sesuai untuk mengukur kecekapan. Tiga model APD yang diuji ialah BCC, CCR dan TT. Data kajian merangkumi data input dan output institusi wakaf di Malaysia yang merangkumi tahun 2014 hingga 2021. Bagi Model BCC dan CCR, 4 data input digunakan terdiri daripada perbelanjaan kutipan dana, perbelanjaan gaji kakitangan, perbelanjaan operasi dan kutipan dana wakaf tunai. Manakala 2 data output merangkumi nilai projek wakaf dan keuntungan pelaburan dana wakaf tunai. Berbeza dengan Model TT yang mempunyai tambahan data baharu menerusi aktiviti bawaan atau peralihan iaitu kutipan dana wakaf tunai. Keputusan kajian menunjukkan Model BCC mengatasi dua model lain. Penemuan ini mengukuhkan dan mempertingkatkan kedudukan Model BCC sebagai APD termaju yang menggabungkan andaian yang lebih tepat melalui Pulangan Berubah Mengikut Skala. Penemuan kajian dijangka menawarkan pandangan yang berharga kepada ahli akademik, menunjukkan bahawa model berasaskan andaian yang lebih realistik mempunyai kesan yang lebih besar, menggambarkan kecekapan sebenar dengan tepat dan mendedahkan kesinambungan aktiviti bawaan atau peralihan yang tidak membantu dalam memberikan skor kecekapan yang lebih tinggi. Tambahan pula, adalah penting untuk mengakui kepentingan menggabungkan Model BCC dengan model lain sebagai penanda aras perbandingan dalam mana-mana kajian yang berkaitan dengan APD.
Synergistic Effect of Plant Growth Promoting Rhizobacteria and Cirsium arvenseagainst Black Scurf Disease of Potato
Authors: Ali Zohaib Karamat , Bashir Uzma , Khan Iqra Haider , Javaid Arshad , Anwar Waheed
Published: September 2024

Potato (Solanum tuberosum L.) is an important cash crop of Pakistan. Black scurf of potato is a very important disease that is caused by Rhizoctonia solaniKühn. In this study, management of black scurf of potato was done through biocontrol method by using plant growth promoting rhizobacteria (PGPR) and dry biomass of a weed, Cirsium arvense(L.) Scop. In vitro antagonistic interactions were carried out to assess the potential of two strains of PGPR namely Bacillus megaterium ZMR6 and Pseudomonas fluorescence PF180 against the fungal growth. P. flourescensshowed marked antagonistic activity causing 65% reduction in growth of the fungus as compared to 43% reduction due to B. megaterium. Likewise, in laboratory bioassays, methanolic extract of 2, 4 and 6% concentrations of leaf, stem, and root of C. arvense reduced biomass of R. solaniby 64-71%, 42-53% and 26-47%, respectively. In pot experiment, the two PGPR species and different doses of C. arvensedry biomass (CDB) viz. 1, 2 and 3% (w/w) were used as soil amendment separately as well as in combination to control the disease. There were 13 treatments, which included a negative control; a positive control (R. solanionly); 1, 2 and 3% CDB (separately) together with R. solani, two PGPR species (separately) plus R. solani; different combinations of two PGPR species and CDB together with R. solani. Potato variety Sante was used as test plant. The highest disease incidence (91%) and disease severity (rating scale 4) were observed in positive control (with R. solani only). R. solanisignificantly reduced biomass of tubers by 52% over negative control. All the treatments significantly enhanced tuber biomass by 18-166% over positive control. The best combination was 3% CDB + P. florescence where minimum disease incidence (3%) and severity (mean disease rating 0.2) were recorded. This treatment also showed the highest tubers yield that was 29% and 166% higher as compared to negative and positive control treatments, respectively. It concluded that P. florescence in combination with 3% dry biomass of C. arvensecan control black scurf disease and enhance potato yield.
TYPOLOGY OF NEGATIVE CONSTRUCTIONS IN WEST GERMANIC LANGUAGES
Authors:   Borys Grinchenko Kyiv Metropolitan University, Kyiv, Ukraine, Horodilova Tetiana Mykolayivna
Published: September 2024

The article displays a typological analysis of negation in West Germanic languages. The attention is focused on the structural characteristics of negative sentences in the languages under consideration. Present-day West Germanic languages exhibit singular negation pattern, which is different from the Old Germanic one. There have been highlighted the changes that took place in the system of sentence negation in the history of West Germanic languages. At the early stages of their development the languages in question demonstrated double negation, that is, the phenomenon of negative concord. It is characterized by two or more negative markers resulted in a single semantic core of negation. On the evolutionary path preverbal negative particles were eliminated from the negation pattern both due to their weakening and the rise of a new negative element. The last one was grammaticalized from the structurally full-content lexical unit wiht ‘thing’ into a relatively independent particle. The rise of the additional reinforcing element is considered to be a part of the common Germanic negation pattern. The English language with its AUX VERB NOT pattern, different from the other West Germanic languages, occupies a special place in the picture of West Germanic negation. The gradual changes, which occurred as a result of the general restructuring of language systems, led to the elimination of redundant elements. Despite individual character and systemic differences, German, Dutch, English, and Frisian went through a common path of eliminating redundant elements and established grammaticalized negation patterns in their present-day form. The given discussion makes it possible to justify the assumption about common shifts in formation of the Old Germanic negation pattern, namely, the linguistic constant.
THE PSYCHOLOGICAL PORTRAIT OF JUDAS ISCARIOT IN THE SHORT STORY BY DAZAI OSAMU “AN URGENT APPEAL”
Authors:   Ivan Franko National University of Lviv, Lviv, Ukraine, Horoshkevych Olena Heorhiyivna
Published: September 2024

The article analyzes the psychological portrait of Judas Iscariot, drawn by a Japanese writer of the 20th century Dazai Osamu in the short story “An Urgent Appeal”. We see the goal of this article in revealing the features of the author`s psychoanalytic of this image. Methods of contextual analysis, comparative analysis, biographical and hermeneutic analysis were used. The reasons for the author`s appeal to Christian themes and biblical images are considered$ peculiarities of the narrative of the work$ intertextual connections of the work with the texts of the Gospels; reception of the work in Japanese literary discourse. According to the form of the narrative, it is the confession of one hero, presented as a stream of feverish consciousness driven to insanity. The narrative of the story has a frame structure: the dotted frame is the address of the narrator (Judas Iscariot) to someone who has the authority to seize and punish Jesus; embedded stories – scene from the Bible and their perception by Judas. In a feverish confession full of contradictions, the reader is presented with a character with a narcissistic grandeur complex who is driven to crime by the maddened passions raging in his soul. The tragic mode of the work can be seen in the analysis of the character’s obsession, the depiction of his pathological mental state. That is, the understanding of the archetype of the traitor in the story of Dazai Osamu takes the form of a psychoanalytic analysis: the tragedy of an ordinary person is described, who found himself next to someone whose greatness and nature of this greatness he could not understand. Prospects for further research can be seen in the analysis of Christian motifs and images in other works of Dazai Osamu. As well as in the analysis of the intertextual component in the works of this autor.
SCALAR GRADATION OF EPISTEMIC WORDS TO DENOTE DOUBT/CONFIDENCE
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Xiaomeng Le
Published: September 2024

This article analyzes the scalar gradation of epistemic words expressing doubt and confidence. To measure the degree of confidence, a confidence scale is introduced, with negation and affirmation at opposite ends. The research material consists of epistemic words with the semantics of doubt and confidence, selected from 10 interviews in Russian, totaling 18,205 characters. During the analysis, epistemic verbs were classified into two categories based on the degree of expression of confidence and doubt: 1) verbs of opinion and assumption, and 2) verbs of knowledge and confidence. Our calculations indicate that verbs of knowledge dominate media discourse, reflecting the speaker’s confidence in their message and their desire to influence conversation participants. In addition to epistemic verbs, epistemic modality can also be expressed through introductory words and other modal elements. These elements are categorized into affirmative and conjectural based on their degree of reliability. In the reviewed media texts, epistemic verbs are more frequently used than epistemic modal words. Linguistic means with the semantics of conjecture are employed much more often than affirmative modal elements. This is likely because the speaker wants to leave room for maneuvering in the dialogue, thereby making the expressions more indirect and euphemistic. Our analysis shows that doubt is close to complete denial but not equivalent to it; confidence is close to affirmation but not equivalent to it. There is no clear transition between direct denial and doubt, doubt and assumption, assumption and certainty, or certainty and affirmation.
Application of Foresight Technology inVocational Guidance Work with Students of Pre-university Educational Institutions Ministries of Defense of the Russian Federation
Authors: Antsibor Y.A.
Published: September 2024

The article presents the results of a case study on the use of innovative tools when conducting career guidance work with students of pre-university educational organizations of the Ministry of Defense of the Russian Federation. The specifics of these organizations leave their mark on the forms and methods of career guidance work with students and require the search and implementation of new, effective forms of work. The study involved 161 students in grades 10-11 of the Moscow Suvorov Military School, 50% of whom were additionally given a cycle of classes throughout the year based on the foresight session method. To assess the impact of foresight technology on the quality of career guidance work, the questionnaires «Military Professional Motivation» (B.V. Ovchinnikov, A.F. Borovikov) and «Readiness for Military Professional Activity», developed at the Moscow Suvorov Military School, were used. The results obtained confirmed the effectiveness of using foresight technology in working with students to develop military-professional motivation.
Professional Burnout of Secondary School Teachers under Conditions of a Terrorist Threat
Authors: Senatorova E.N. , Balan A.S. , Gatsutsyn V.V.
Published: September 2024

This study aims to clarify the methodological status of the category “activity experience”. The characteristics of professional burnout and work passion among teachers from two regions are studied: a region with an indefinitely high (yellow) level of terrorist threat and a regular region. Subjects: 29 people. Group 1: 10 people – school teachers from a region with a terrorist threat, 20% men, 80% women, average age: 49.5 years. Group 2; 19 people from a region with no terrorist threat, 16% men, 84% women, average age: 41.2 years. Methods: Questionnaire “Utrecht Work Engagement Scale” adapted by D.A. Kutuzova, Maslach Burnout Questionnaire in Russian adaptation), Mann-Whitney U-criteria for unmatched groups. Results: the yellow level of terrorist threat in the region has an impact on the work of educational organizations (some classes are held remotely, the load associated with ensuring the safety of the educational institution increases). However, no differences were found in indicators of work passion (enthusiasm, energy, involvement) between teachers in different regions. There are also no differences in overall professional burnout and indicators of emotional exhaustion and depersonalization. The reduction in professional achievements among teachers from a region with a terrorist threat is significantly lower. Conclusions: the terrorist threat that lasts for six months does not have a direct impact on professional burnout and work commitment of teachers in the region. Perhaps it corresponds to the first stage of stress (anxiety) development, when internal resources are mobilized. Teachers need psychological support to prevent the development of deeper stages of stress.
Diplomatic Relations and Intercultural Communication of the Russian Empire and the Kingdom of Italy in the Risorgimento Era
Authors: Dergacheva I.V.
Published: September 2024

The article provides an analysis of the document circulation that occurred during the period of Risorgimento as a result of the diplomatic relations between Italy, including the Vatican, and the Russian empire. The funds of the Archive of Foreign Policy of the Russian Empire (AFPRE) of the Ministry of Foreign Affairs were examined and individual documents giving an idea of close diplomatic and intercultural relations between the two countries were analyzed and put into scientific circulation for the first time. In addition, the materials of the Russian State Historical Archive (Petersburg), also concerning the established links between the Russian Empire and the Papal States, were analyzed and for the first time introduced into scientific circulation.
The Assessment of “Sick Talent” as an Oxymoron
Authors: Ledeneva V.V.
Published: September 2024

Based on the material of the epistolary of the 90s of the 19th century, N.S. Leskov's perception of the oxymoron characteristic "sick talent" in relation to his personality and creativity is comprehended; the volume of semantics of the word "talent" in the writer's mental and linguistic complex is analyzed as one of the means of broadcasting the concept of "Giftedness".
The Role of Data Engineering in Facilitating Ps5 Launch Success: A Case Study
Authors: Paulraj Balachandar
Published: September 2024

The paper presents the role of data engineering in the successful launch of PS5 by Sony Interactive Entertainment. It underlines the analysis of how data has been used for optimising supply chains, improving system performance, shaping marketing strategy, and bringing critical support during console development and release. It follows that through secondary research and thematic analysis, such findings allow the understanding that data engineering at Sony enabled it to surmount issues of global supply chain disruption, improve the loading time in games, and offer personalised customer engagement. These would also account for the commercial success of the PS5 while setting new industry standards for future gaming consoles. This substantiates the use of data engineering in developing not only operational efficiency but also consumer satisfaction.
Sklerostin ve Wnt Sinyal Yolu Arasındaki İlişki
Authors: Şemsi Rabia , Sepici Dinçel Aylin
Published: September 2024

Sklerostin, kemik metabolizmasında ve iskelet bozukluklarında önemli rol oynayan bir glikoproteindir. Omurgalılar arasında yüksek oranda korunmuş olan SOST geninden üretilir. Sklerostin üreten kemik hücreleri olan osteositler, bu proteini osteoblastlardaki kanonik Wnt sinyal yolunu antagonize etmek için kullanır. Bu yol, osteoblastların çoğalmasını, farklılaşmasını ve hayatta kalmasını desteklediği için kemik oluşumu için gereklidir. Bununla birlikte, sklerostin bu yolu inhibe ettiğinde, yeni kemik dokusu üretimini azaltır. Hayvanlar üzerinde yapılan çalışmalar, mekanik yüklemenin SOST gen ekspresyonunu azaltarak osteositlerde sklerostin sentezini azaltabileceğini göstermiştir. Bu, kemikler egzersiz veya ağırlık kaldırma gibi mekanik strese maruz kaldığında, SOST geninin ifadesinin azaldığı ve sklerostin üretiminde bir azalmaya yol açtığı anlamına gelir. Bu azalma da Wnt sinyalinin ve kemik oluşumunun artmasını sağlar. Tersine, uzun süreli hareketsizlik dönemlerinde olduğu gibi mekanik yük ortadan kalktığında, sklerostin sentezi artarak kemik oluşumunda azalmaya yol açar. Sklerostinin kemik oluşumunu engellemesi, yüksek kemik kütlesine sahip çeşitli hastalıklarla ilişkilendirilmiştir. Örneğin sklerostin eksikliği, kemik yoğunluğunun ve kalınlığının artmasıyla karakterize nadir bir genetik bozukluk olan sklerosteoza yol açar. Benzer şekilde, van Buchem hastalığı olarak bilinen başka bir nadir genetik bozukluk, SOST genindeki bir mutasyondan kaynaklanır ve bu da sklerostin üretiminde bir azalmaya ve kemik yoğunluğunun artmasına neden olur. Bu derleme, Wnt sinyalizasyonunun temellerini, kemik metabolizması ve iskelet bozukluklarındaki rolünü tartışmaktadır. Ayrıca kemik sağlığını etkileyen iki yaygın durum olan osteoporoz ve osteoartritte Wnt sinyalinin klinik önemini ve gelecekteki etkilerini de değerlendirmektedir. Genel olarak, sklerostin ve Wnt sinyalizasyonunun karmaşık mekanizmalarını anlamak, kemikle ilgili hastalıklar için yeni tedaviler geliştirmek ve kemik sağlığını iyileştirmek için çok önemlidir
Disarmament in history and at present: theory vs practice
Authors: Arbatov A.G.
Published: September 2024

Without delving into medieval history, we can expect that after World War I, disarmament issues became an important object of world politics, and after World War II, they took a central place in it. The monstrous destructive power, speed and constant readiness of nuclear weapons, capable of destroying entire states in a few hours, have fundamentally transformed the dialectics of politics and war.
Clausewitz’s sacramental formula: “War is (:ontimiation of the policy by other, violent means” - has now become a street with a ‘two-way movement.' These violent means are tangible, influence politics, and sometimes dictate the rules for its behavior. Hence the logic of disarmament: influencing the means of war through agreements on their limitation and elimination to reduce the likelihood of war, to reduce its destructive effects and the economic costs of an arms race. However, practice has shown that these elements of the classical ‘triad’ of disarmament do not always harmoniously complement each other, and often come in conflict with each other. Fundamental disarmament issues remain unresolved to this day or are being re-initiated as the world order changes and science and technology develop. Worse, at the moment, the collapse of the disarmament treaty system built over decades is leading to a new arms race, while there is a possibility of transferring control over their use to supercomputers. At the same time, the half-century history of disarmament negotiations has shown that, with the creation of favorable political conditions, compromises are achievable on the most complex strategic and technical issues - with the goodwill of government leaders, the support of political elites and the persistent efforts of military and civilian professionals.
Responsible urban development policy: criteria, subjects, prospects
Authors: Bardin A.L. , Pantin V.I.
Published: September 2024

This article examines the primary directions of contemporary urban development policy, along with the issues and contradictions associated with its scientific research and practical implementation. The study aims to conceptualize the concept of “responsible urban development” as a complex of approaches and practices that hold promise for integration into practical urban and regional development policies, and to typologize potential approaches to implementing such policies. The authors use an institutional approach, the methodology of identity studies, the structural-functional approach and a case study. The article investigates quantitative and qualitative indicators, the key challenges and tasks of urban development policy, with a particular focus on the resources of modern urban development. The authors note that relying on a limited set of indicators does not provide the capacity for decision-making necessary to update and transform urban development policy to ensure its ability to promptly and flexibly respond to the numerous problems and challenges arising under conditions of socio-political instability. The article addresses and analyses several cases of contemporary urban development and the implementation of corresponding policies. Based on this analysis, the authors conclude that one of the central and most pressing issues in the policy of responsible urban development and the socio-political dynamics of cities is the inefficiency of the communication process between civil actors and stakeholders, on the one hand, and city authorities and the city administration, on the other. This communication deficit can only be partially addressed through digitalization, as the primary obstacles to improved communication are administrative barriers and the dominance of the interests of certain groups, such as large corporations and financial institutions.
Ideological segmentation of mass strata of the population under conditions of aggravated confrontation with the West (empirical analysis)
Authors: Tikhonova N.E.
Published: September 2024

Using the data from surveys conducted by IS FCTAS RAS over a number of years, it is shown that despite the absence of the segmentation traditionally used for ideological structuring in the mass strata of the population, it still exists, but is based on different grounds. Moreover, the importance of ideological contradictions in the perception of Russians themselves has grown significantly over the past decade, and the majority of the country's citizens now have internally consistent ideological views. The comparative role of their various components changes over time under the influence of external events. The main line of demarcation in the ideological segmentation is the attitude to the West in modern conditions, which is based on different attitudes to the civilizational specifics of Russia and, in turn, influences their assessment of the vector of the country's development, their trust in the authorities, attitude to the special military operation, etc. It is also shown that in recent years, in the course of active crystallization and polarization of ideological views of Russians', an ideological majority and an ideological minority have been formed in the country, comprising almost two-thirds and about one-third of the population, respectively. The normative-value basis of the former is the recognition of the priority of state interests over human rights and the conviction that Western values are not suitable for Russians. The ideological majority is divided into a core and a peripheral group, which differ in the degree of consistency of their views and assessments, including those regarding to the special military operation in Ukraine. The ideological minority, which is characterized by the desire for Russia to adhere to the norms proposed by Western countries, is also heterogeneous. It includes, firstly, a group that is consistent in its negative attitude towards the current course of Russia, which makes up about a quarter of the population, and whose moods are primarily influenced by the unfavorable socio-economic situation these people are experiencing. The other group includes representatives who are loyal to the authorities and the course being implemented but would like Russia to follow the Western-oriented path in future. The normative value basis of the views of the members of the ideological minority is the recognition of the priority of human rights over the interests of the state.
Edukasi life skills pencegahan perilaku bermasalah pada siswa sekolah menengah pertama
Authors: Riskiyani Shanti , Thaha Ridwan Mochtar , Seftiani Chintia , Haris Alfina Riyanti , Linggi Irayanti Randa , Ningtyas Chikita Alya Cahya , Lazarus Jonathan , Dorliyanti Emy , Rachmat Muhammad
Published: September 2024

Life skills atau kecakapan hidup adalah kemampuan untuk menyesuaikan diri dan melakukan suatu perilaku tidak menyimpang yang bertujuan agar setiap individu bisa menghadapi persoalan dalam kehidupannya, khususnya bagi remaja. Kegiatan edukasi ini bertujuan meningkatkan pengetahuan dan pemahaman siswa tentang life skills pencegahan perilaku bermasalah berupa perilaku merokok, konsumsi alkohol, dan penggunaan obat-obatan terlarang pada siswa SMP, serta dapat memahami life skills yang sesuai sebagai bentuk pencegahan terhadap perilaku bermasalah. Edukasi ini dilakukan dengan cara pemaparan materi menggunakan metode ceramah dan curah pendapat yang diikuti oleh 20 orang siswa kelas tujuh, serta melibatkan peserta kegiatan untuk ikut berperan aktif dalam diskusi terkait perilaku bermasalah. Hasil analisis menggunakan uji Wilcoxon signed rank menunjukkan perbedaan skor pengetahuan peserta sebelum dan sesudah diberikan edukasi (p-value=0,043; p<0,05). Hasil ini diharapkan dapat mencegah perilaku bermasalah pada siswa SMP seperti perilaku merokok, konsumsi alkohol, dan penggunaan obat-obatan terlarang dan mengembangkan potensi manusiawi peserta didik untuk menghadapi perannya di masa yang akan datang.
Comparative efficacy of autologous platelet rich plasma and conventional dressing in the management of chronic ulcers
Authors: Bishnoi Anuj , Gupta Jagdish , Verma Neeraj , Bishnoi Monika , Chauhan Pallavi , Chaudhary Mayank
Published: September 2024

Background: Chronic ulcers pose a major global healthcare challenge. The use of platelet-rich plasma (PRP) for treating these wounds has garnered interest because of its potential healing benefits. Objective were to determine the effect of autologous PRP therapy on the percentage of surface area reduction/healing in chronic ulcers.
Methods: This randomized controlled trial was conducted at the department of general surgery of M.M. institute of medical sciences and research (M.M.I.M.S.R.) Mullana, Ambala from May 1, 2023, to April 30, 2024. Patients aged 18-80 years of either gender with chronic ulcers were enrolled. Patients were randomly allocated to the PRP group and control group. PRP group was administered autologous PRP once in two weeks for 6 weeks after debridement, while for the control group conventional saline dressings were done after debridement. Final assessment was done at 8 weeks.
Results: Of the 60 patients, the mean age was 53.90±11.23 years. There were 49 (82%) males and 11 (18%) females. At 8 weeks, the PRP group achieved 83.78% (SD=2.99) reduction in surface area of ulcers, whereas the control group had a 57.78% (SD=1.32) reduction in surface area of ulcers, with a p=0.0000 indicating a significant difference. The small sample size and 56-day follow-up period are insufficient to assess long-term treatment effects.
Conclusions: A better outcome of PRP was observed compared to conventional dressing in patients with chronic non-healing ulcers.
Well differentiated squamous cell carcinoma mimicking occipital lipoma
Authors: Ohiaeri Ikenna Chimuanya , Egboduku Emmanuel
Published: September 2024

Squamous cell carcinoma is the second most common cancer arising from keratinocytes which can present as benign lesions. We present a case of well differentiated carcinoma mimicking an occipital lipoma. A 39-year-old female presented with occipital swelling of 8 years duration with associated pain which on examination showed a firm, well-defined lobulated, mildly tender mass attached to the skin but not underlying structures. Ultrasound showed lipoma with degenerative changes and histology showed well differentiated squamous cell carcinoma. She subsequently had wide local excision. Our case is similar to other reports showing squamous cell carcinoma resembling benign conditions. There is therefore a need to have a high index of suspicion when evaluating benign lesions especially of the scalp.
Expert perspectives on the prescription pattern of levocetirizine₊montelukast and fexofenadine₊montelukast for the management of allergic rhinitis in the Indian settings
Authors: S. Manjula , M. Krishna Kumar
Published: September 2024

Background: Studies have shown that oral antihistamines are considered as the gold-standard therapy for allergic rhinitis. However, there is dearth of studies among clinicians, so this study aimed to gather expert opinion on the prescribing pattern of levocetirizine₊montelukast and fexofenadine₊montelukast for managing AR in India.
Methods: This cross-sectional study, conducted through a multi-response questionnaire comprising 24 questions, gathered insights from experts across diverse Indian settings. It explored perspectives on clinical observations, experiences, demographic profiles, treatment characteristics in AR, and the utilization of fexofenadine₊montelukast and levocetirizine₊montelukast for AR management in clinical practice. The data were analyzed through descriptive analysis.
Results: Majority of clinicians (52%) preferred levocetirizine₊montelukast for AR, with half of them recommending a 2-week course. Additionally, 38% of clinicians noted its effectiveness in addressing all AR symptoms. Most clinicians agreed that levocetirizine and montelukast combination therapy was effective in improving nighttime nasal symptoms (74%) and nasal congestion (69%). Furthermore, majority of clinicians acknowledged that the combination offers both immediate (74%) and long-term (56%) relief from AR symptoms. Approximately 58% of the healthcare providers reported overall improvement across categories with fexofenadine₊montelukast, encompassing daytime nasal symptoms, nighttime nasal symptoms, and daytime eye symptoms.
Conclusion: Clinicians recommended the combination of levocetirizine₊montelukast and fexofenadine₊montelukast to manage AR. Levocetirizine₊montelukast combination was preferred by clinicians for its efficacy in alleviating nighttime nasal symptoms and congestion. Fexofenadine₊montelukast combination was also endorsed for overall improvement across various symptoms.
The impact of mitomycin C in endoscopic sinus surgeries: a comprehensive review
Authors: Manglik Shivangi , Kalra Vijay
Published: September 2024

Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinus linings, often resulting in various debilitating symptoms. Functional endoscopic sinus surgery (FESS) is a common treatment for CRS, aiming to alleviate symptoms by restoring sinus drainage and mucosal repair. However, postoperative complications, including adhesion formation, remain a concern. This systematic review aims to evaluate the effectiveness of mitomycin-C (MMC) in reducing postoperative complications, particularly adhesion formation, in patients undergoing ESS. A systematic review of available evidence on the role of MMC in FESS was conducted. Studies were selected based on predefined inclusion criteria, and relevant data were extracted and synthesized. Nineteen studies met the inclusion criteria, encompassing a total of 763 subjects. The majority of studies reported a reduction in postoperative adhesion formation with MMC use, although statistical significance varied. MMC dosages and application methods varied across studies, contributing to heterogeneity in outcomes. Overall, MMC showed promise in reducing adhesion formation and improving surgical outcomes in FESS. However, further high-quality, prospective, randomized controlled trials are warranted to establish optimal dosage, application methods, and long-term efficacy of MMC in FESS for CRS.
A rare expediting killer-primary thyroid gland sarcoma
Authors: Ghin Ern Annie Chieng , Hong Wong Chyau , Yahya Mohammad Nasyatmuddin , Tang Chian Ling
Published: September 2024

Primary thyroid malignancies can be classified into differentiated type (follicular, papillary, medullary, and anaplastic) and un-differentiated type or non-epithelial malignancies, particularly lymphomas and sarcomas. The reported frequency of primary thyroid sarcoma (PTS) cases ranges from 0.01% to 1.5%. Based on this fact, we present a case report of rare primary thyroid sarcoma (PTS) in Hospital Sibu, Sarawak. Our patient is a 78-year-old lady with multiple co-morbidities and her clinical deterioration is so rapid that its progression mimics thyroid anaplastic carcinoma which is commonly seen in female elderly as well. To diagnose such uncommon thyroid malignancy, the histopathology of the tumour needs to be conducted with immunohistochemical staining. Radiographic imaging such as computed tomography or magnetic resonance imaging of whole body is required for staging purpose and to look for metastasis. We analyze the clinical presentations of PTS and discuss its treatment and prognosis. The treatment of PTS must be assessed individually on case-by-case basis as currently there is no general consensus on treating this cancer.
Cemento-ossifying fibroma: an extensive fibro-osseous lesion involving paranasal sinuses
Authors: Patel Reena , Parelkar Kartik , Puthenpurayil Susanna jose , Kothiya Mayur Rameshbhai
Published: September 2024

Cemento-ossifying fibroma (COF) is a fibro-osseous lesion arising from cells of the periodontal ligament. This tumor typically occurs in individuals during their third and fourth decades of life, with a predilection for women. COF primarily affects the maxillofacial region, most commonly the mandible. Its localization in the paranasal sinuses and skull base is unusual. However, we present a rare case of COF involving the right paranasal areas of the maxillofacial region in an 18-year-old female. Computed tomography (CT) revealed an expansile lesion measuring 52.45×32×74.29 mm involving the right maxillary sinus, expanding into both the anterior and posterior choanae. The patient underwent endoscopic sinus surgery (ESS) with preservation of adjoining vascular structures. Clinical, radiographic, and histologic features are presented, and differential diagnosis is discussed.