bluuebunny/crossref_metadata_2025 huggingface dataset:
Boundaries of the X Phases in Sb–Te and Bi–Te Binary Alloy Systems
Authors: Kifune Kouichi , Wakiyama Takuya , Kanaya Hiroki , Kubota Yoshiki , Matsunaga Toshiyuki
Published: August 2019

Sb–Te and Bi–Te compounds are key components of thermoelectric or phase change recording devices. These two binary systems form commensurately/incommensurately modulated long-period layer stacking structures known as homologous phases that comprise discrete intermetallic compounds and X phases. In the latter, the homologous structures are not discrete but rather appear continuously with varying stacking periods that depend on the binary composition. However, the regions over which these X phases exist have not yet been clarified. In this study, precise synchrotron X-ray diffraction analyses of various specimens were conducted. The results demonstrate that the X phase regions are located between Sb20Te3 and Sb5Te6 in the Sb–Te system and between Bi8Te3 and Bi4Te5 in the Bi–Te system.
Effect of Annealing Ambient on SnO2 Thin Film Transistors Fabricated via An Ethanol-based Sol-gel Route
Authors: Lee Hyunjae , Ha Seunghyun , Bae Jin-Hyuk , Kang In-Man , Kim Kwangeun , Lee Won-Yong , Jang Jaewon
Published: August 2019

The effect of annealing ambient on SnO2 thin-film transistors (TFTs) fabricated via an ethanol-based sol-gel route was investigated. The annealing ambient has a significant effect on the structural characteristics and chemical composition and, in turn, the device performance. Although the crystalline-grain size of the SnO2 films annealed in air was the smallest, this size yielded the highest field-effect mobility. Compared with the minimization of boundary scattering via crystalline-size increase, augmentation of the free carrier concentration played a more critical role in the realization of high-performance devices. The fabricated SnO2 TFTs delivered a field-effect mobility, subthreshold swing, and on/off current ratio of 10.87 cm2/Vs, 0.87 V/decade, and 107, respectively.
Dynamic Motion Planning for Autonomous Assistive Surgical Robots
Authors: Sozzi Alessio , Bonfè Marcello , Farsoni Saverio , De Rossi Giacomo , Muradore Riccardo
Published: August 2019

The paper addresses the problem of the generation of collision-free trajectories for a robotic manipulator, operating in a scenario in which obstacles may be moving at non-negligible velocities. In particular, the paper aims to present a trajectory generation solution that is fully executable in real-time and that can reactively adapt to both dynamic changes of the environment and fast reconfiguration of the robotic task. The proposed motion planner extends the method based on a dynamical system to cope with the peculiar kinematics of surgical robots for laparoscopic operations, the mechanical constraint being enforced by the fixed point of insertion into the abdomen of the patient the most challenging aspect. The paper includes a validation of the trajectory generator in both simulated and experimental scenarios.
Microfluidics-Based Four Fundamental Electronic Circuit Elements Resistor, Inductor, Capacitor and Memristor
Authors: Stojanović Goran , Paroški Milivoj , Samardžić Nataša , Radovanović Milan , Krstić Dejan
Published: August 2019

The microfluidics domain has been progressing rapidly recently, particularly considering its useful applications in the field of biomedicine. This paper presents a novel, microfluidics-based design for four fundamental circuit elements in electronics, namely resistor, inductor, capacitor, and memristor. These widely used passive components were fabricated using a precise and cost-effective xurography technique, which enables the construction of multi-layered structures on foil, with gold used as a conductive material. To complete their assembly, an appropriate fluid was injected into the microfluidic channel of each component: the resistor, inductor, capacitor, and memristor were charged with transformer oil, ferrofluid, NaCl solution, and TiO2 solution, respectively. The electrical performance of these components was determined using an Impedance Analyzer and Keithley 2410 High-Voltage Source Meter instrument and the observed characteristics are promising for a wide range of applications in the field of microfluidic electronics.
Predicting Performance of a District Heat Powered Adsorption Chiller by Means of an Artificial Neural Network
Authors: Halon Tomasz , Pelinska-Olko Ewa , Szyc Malgorzata , Zajaczkowski Bartosz
Published: August 2019

In this paper, the feasibility of a multi-layer artificial neural network to predict both the cooling capacity and the COP of an adsorption chiller working in a real pilot plant is presented. The ANN was trained to accurately predict the performance of the device using data acquired over several years of operation. The number of neurons used by the ANN should be selected individually depending on the size of the training base. The optimal number of datasets in a training base is suggested to be 35. The predicted cooling capacity curves for a given adsorption chiller driven by the district heating are presented. Predictions of the artificial neural network used show good correlation with experimental results, with the mean relative deviation as low as 1.36%. The character of the cooling capacity curve is physically accurate, and during normal operation for cooling capacities ≥8 kW, the errors rarely exceed 1%.
A Fast Online State of Health Estimation Method for Lithium-Ion Batteries Based on Incremental Capacity Analysis
Authors: Qu Shaofei , Kang Yongzhe , Gu Pingwei , Zhang Chenghui , Duan Bin
Published: August 2019

Efficient and accurate state of health (SoH) estimation is an important challenge for safe and efficient management of batteries. This paper proposes a fast and efficient online estimation method for lithium-ion batteries based on incremental capacity analysis (ICA), which can estimate SoH through the relationship between SoH and capacity differentiation over voltage (dQ/dV) at different states of charge (SoC). This method estimates SoH using arbitrary dQ/dV over a large range of charging processes, rather than just one or a limited number of incremental capacity peaks, and reduces the SoH estimation time greatly. Specifically, this method establishes a black box model based on fitting curves first, which has a smaller amount of calculation. Then, this paper analyzes the influence of different SoC ranges to obtain reasonable fitting curves. Additionally, the selection of a reasonable dV is taken into account to balance the efficiency and accuracy of the SoH estimation. Finally, experimental results validate the feasibility and accuracy of the method. The SoH estimation error is within 5% and the mean absolute error is 1.08%. The estimation time of this method is less than six minutes. Compared to traditional methods, this method is easier to obtain effective calculation samples and saves computation time.
A Novel Direct Load Control Testbed for Smart Appliances
Authors: Garrido-Zafra Joaquín , Moreno-Munoz Antonio , Gil-de-Castro Aurora , Palacios-Garcia Emilio J. , Moreno-Moreno Carlos D. , Morales-Leal Tomás
Published: August 2019

The effort to continuously improve and innovate smart appliances (SA) energy management requires an experimental research and development environment which integrates widely differing tools and resources seamlessly. To this end, this paper proposes a novel Direct Load Control (DLC) testbed, aiming to conveniently support the research community, as well as analyzing and comparing their designs in a laboratory environment. Based on the LabVIEW computing platform, this original testbed enables access to knowledge of major components such as online weather forecasting information, distributed energy resources (e.g., energy storage, solar photovoltaic), dynamic electricity tariff from utilities and demand response (DR) providers together with different mathematical optimization features given by General Algebraic Modelling System (GAMS). This intercommunication is possible thanks to the different applications programming interfaces (API) incorporated into the system and to intermediate agents specially developed for this case. Different basic case studies have been presented to envision the possibilities of this system in the future and more complex scenarios, to actively support the DLC strategies. These measures will offer enough flexibility to minimize the impact on user comfort combined with support for multiple DR programs. Thus, given the successful results, this platform can lead to a solution towards more efficient use of energy in the residential environment.
Pathway Analysis of a Zero-Emission Transition in the Nordic-Baltic Region
Authors: Lund Peter D. , Skytte Klaus , Bolwig Simon , Bolkesjö Torjus Folsland , Bergaentzlé Claire , Gunkel Philipp Andreas , Kirkerud Jon Gustav , Klitkou Antje , Koduvere Hardi , Gravelsins Armands , Blumberga Dagnija , Söder Lennart
Published: August 2019

A zero-emission pathway for the Nordic and Baltic region in Europe is described based on the comprehensive policy and scenario analyses, accompanied by energy system modelling. The analyses show that a least-cost strategy would massively employ renewable energy, particularly in the power sector. Through strong coupling across energy sectors and countries, electricity would play a central role in the decarbonization of the main energy sectors. In particular power-to-heat conversion, where heat storage appears important in addition to existing hydropower. Technical and regulatory barriers in front of increased sector coupling and flexibility were identified, and policy measures are proposed to overcome these. In addition to a high carbon price, dynamic tariffs and taxation of electricity would be important to allow market signals for flexibility to reach end-users. A stronger power transmission connection from the Nordics to the mainland-Europe and the United Kingdom would be beneficial for the emission reductions and renewable energy use. The transition pathway analysis points out socio-technical issues such as social acceptance of large-scale new infrastructures (e.g., wind, cables). The energy system optimizations indicate that most of the investments needed for the zero-emission pathway until 2050 would take place already by 2030.
Analysis of Oil Price Effect on Economic Growth of ASEAN Net Oil Exporters
Authors: Kriskkumar Karunanithi , Naseem Niaz Ahmad Mohd
Published: August 2019

In this paper, the linear and nonlinear effects of oil price on growth for Association of Southeast Asian Nations (ASEAN)—3 net oil-exporting countries, namely Brunei, Malaysia and Vietnam, are investigated. The empirical analysis applies the augmented autoregressive distributed lag model (ARDL) bound test approach and the nonlinear autoregressive distributed lag model (NARDL) methodology over the period of 1979 to 2017. Evidence suggests that ignoring nonlinearities may lead to misleading results. Specifically, results reveal that the effect of oil price is asymmetric for the case of Brunei, while the effect oil price is deemed insignificant for the case of Malaysia and Vietnam, both linear and nonlinear model. Brunei’s high dependency on oil revenue makes it susceptible to negative oil price shock. This suggests that oil price still plays a significant role as the main driver of economic progress for Brunei.
Looking at the Origin: Some Insights into the General and Fermentative Microbiota of Vineyard Soils
Authors: Alonso Alejandro , de Celis Miguel , Ruiz Javier , Vicente Javier , Navascués Eva , Acedo Alberto , Ortiz-Álvarez Rüdiger , Belda Ignacio , Santos Antonio , Gómez-Flechoso María Ángeles , Marquina Domingo
Published: August 2019

In winemaking processes, there is a current tendency to develop spontaneous fermentations taking advantage of the metabolic diversity of derived from the great microbial diversity present in grape musts. This enological practice enhances wine complexity, but undesirable consequences or deviations could appear on wine quality. Soil is a reservoir of important microorganisms for different beneficial processes, especially for plant nutrition, but it is also the origin of many of the phytopathogenic microorganisms that affect vines. In this study, a meta-taxonomic analysis of the microbial communities inhabiting vineyard soils was realized. A significant impact of the soil type and climate aspects (seasonal patterns) was observed in terms of alpha and beta bacterial diversity, but fungal populations appeared as more stable communities in vineyard soils, especially in terms of alpha diversity. Focusing on the presence and abundance of wine-related microorganisms present in the studied soils, some seasonal and soil-dependent patterns were observed. The Lactobacillaceae family, containing species responsible for the malolactic fermentation, was only present in non-calcareous soils samples and during the summer season. The study of wine-related fungi indicated that the Debaryomycetaceae family dominates the winter yeast population, whereas the Saccharomycetaceae family, containing the most important fermentative yeast species for winemaking, was detected as dominant in summer.
Fire Exclusion Destroys Habitats for At-Risk Species in a British Columbia Protected Area
Authors: Hoffman Kira M. , Wickham Sara B. , McInnes William S. , Starzomski Brian M.
Published: August 2019

Fire exclusion and suppression has altered the composition and structure of Garry oak and associated ecosystems in British Columbia. The absence of frequent low severity ground fires has been one of the main contributors to dense patches of non-native grasses, shrubs, and encroaching Douglas-fir trees in historical Garry oak dominated meadows. This case study uses remote sensing and dendrochronology to reconstruct the stand dynamics and long-term fire history of a Garry oak meadow situated within Helliwell Provincial Park located on Hornby Island, British Columbia. The Garry oak habitat in Helliwell Park has decreased by 50% since 1950 due to conifer encroachment. Lower densities and mortalities of Garry oak trees were associated with the presence of overstory Douglas-fir trees. To slow conifer encroachment into the remaining Garry oak meadows, we recommend that mechanical thinning of Douglas-fir be followed by a prescribed burning program. Reintroducing fire to Garry oak ecosystems can restore and maintain populations of plants, mammals, and insects that rely on these fire resilient habitats.
Cyclogenesis and Density Currents in the Middle East and the Associated Dust Activity in September 2015
Authors: Francis Diana , Alshamsi Noor , Cuesta Juan , Gokcen Isik Ayse , Dundar Cihan
Published: August 2019

The first 10 days of September 2015 were marked by intense dust activity over the Middle East and the Arabian Peninsula. This study examines the atmospheric conditions at the origin of the large dust storms during this period. We particularly investigate the atmospheric dynamics leading to the development of a large dry cyclone over Iraq on 31 August 2015 which in turn generated an intense dust storm that affected most of the countries around the Arabian Gulf and lasted for 5 days. We found that the cyclone developed over Northwest Iraq as a transfer to low levels of a cut-off low which had formed two days earlier at upper levels over Turkey. Large dust loads exceeding 250 tons were emitted and moved southeast in a cyclonic shape toward the Arabian sea. The second large dust storm on 6-8 September 2015 occurred over Syria and affected all the coastal countries on the eastern side of the Mediterranean Sea. It was associated with the occurrence of a series of density currents over northeast Syria emanating from deep convection over the mountainous border between Syria and Turkey. The unusual development of deep convection over this area was associated with a blocking high and interaction with orography. Both the cut-off high and the cut-off low occurred during a period characterized by a meandering polar jet and an enhanced subtropical jet causing unstable weather over mid-latitudes which in turn led to highly polluted atmosphere by natural dust in the affected countries.
Magic Lantern Glass Slides Materials and Techniques: The First Multi-Analytical Study
Authors: Rodrigues Beatriz , Santos Ângela , Melo Maria J. , Otero Vanessa , Vilarigues Márcia
Published: August 2019

This paper presents the first systematic investigation of hand-painted magic lantern glass slides using multi-analytical techniques combined with a critical analysis of historical written sources of the painting materials and techniques used to produce them. The magic lantern was an optical instrument used from the seventeenth to the twentieth century that attained great success and impact on the entertainment industry, science, religion, and advertisement industry. The glass, colorants, and organic media of five magic lantern slides from the Museum of Natural History and Science of the University of Lisbon were studied. By means of energy-dispersive X-ray fluorescence spectrometry, the glass was characterized and the oxide quantification unveiled that the glass substrate was possibly produced between 1870 and 1930. Ultraviolet-Visible, Raman and Fourier transform infrared spectroscopies allowed the characterization of the colorants: Prussian blue, an anthraquinone red lake pigment of animal origin (such as cochineal), an unidentified organic yellow, and carbon black. The remaining colors were achieved through mixtures of the pure pigments. Infrared analysis detected a complex fingerprint in all colors, nevertheless, a terpenoid resin such as shellac was identified. Metal carboxylates were also detected, contributing to the assessment of the state of conservation of the paints.
Coupled Stress-Dependent Groundwater Flow-Deformation Model to Predict Land Subsidence in Basins with Highly Compressible Deposits
Authors: Rashvand Mojtaba , Li Jiang , Liu Yi
Published: August 2019

In this study, a stress-dependent groundwater model, MODFLOW-SD, has been developed and coupled with the nonlinear subsidence model, NDIS, to predict vertical deformation occurring in basins with highly compressible deposits. The MODFLOW-SD is a modified version of MODFLOW (the USGS Modular Three-Dimensional Groundwater Flow Model) with two new packages, NONK and NONS, to update hydraulic conductivity and skeletal specific storage due to change in effective stress. The NDIS package was developed based on Darcy–Gersevanov Law and bulk flux to model land subsidence. Results of sample simulations run for a conceptual model showed that hydraulic heads calculated by MODFLOW significantly overestimated for confining units and slightly underestimated for aquifer ones. Moreover, it showed that applied stress due to pumping changed initially homogeneous layers to be heterogeneous ones. Comparison of vertical deformations calculated by NDIS and MODFLOW-SUB showed that neglecting horizontal strain and stress-dependency of aquifer parameters can overestimate future subsidence. Furthermore, compared to the SUB (Subsidence and Aquifer-System Compaction) package, NDIS is more likely to provide a more accurate compaction model for a complex aquifer system with vertically variable compression ( C c ), recompression ( C r ) , and hydraulic conductivity change ( C k ) indices.
Methods of Measuring and Processing Signals during Tests of the Exposure of a Motorcycle Driver to Vibration and Noise
Authors: Figlus Tomasz , Szafraniec Piotr , Skrúcaný Tomáš
Published: August 2019

The paper presents a new method of measuring a motorcycle driver’s exposure to vibration and noise. This method uses the simultaneous measurement of vibration and noise at the points of their direct influence on the motorcycle driver, and the measurement is carried out in real traffic conditions. The vibration of the motorcycle’s handlebars, footrest and seat as well as the noise reaching the beginning of the motorcyclist’s ear canal are recorded. These signals correspond to the direct impact of vibration energy on the upper and lower limbs as well as the torso of a motorcycle driver and the acoustic energy reaching the motorcyclist’s hearing organs. The paper also proposes a signal processing method which enables determination of vibroacoustic effects on the motorcyclist without frequency correction of signals and with taking into account the current standards, and therefore with the use of appropriate frequency corrections. The measurement section of the paper presents examples of results of measurements of the actual exposure of the motorcycle driver to vibration and noise.
A Systematic Review of the Antecedents and Prevalence of Suicide, Self-Harm and Suicide Ideation in Australian Aboriginal and Torres Strait Islander Youth
Authors: Dickson Joanne M. , Cruise Kate , McCall Clare A. , Taylor Peter J.
Published: August 2019

Suicide and self-harm represent serious global health problems and appear to be especially elevated amongst indigenous minority groups, and particularly amongst young people (aged 24 years or younger). This systematic review investigates for the first time the antecedents and prevalence of suicide, self-harm and suicide ideation among Australian Aboriginal and Torres Strait Islander youth. Web of Science, PubMed, PsychINFO, CINAHL databases and grey literature were searched from earliest records to April 2019 for eligible articles. Twenty-two empirical articles met the inclusion criteria. The data confirmed that indigenous youth in Australia have elevated rates of suicide, self-harm and suicidal ideation relative to the nonindigenous population. Risk factors included being incarcerated, substance use and greater social and emotional distress. Notably, though, information on predictors of suicide and self-harm remains scarce. The findings support and justify the increasing implementation of public health programs specifically aimed at tackling this crisis. Based on the review findings, we argued that Aboriginal communities are best positioned to identify and understand the antecedents of youth self-harm, suicide ideation and suicide, and to take the lead in the development of more effective mental health preventive strategies and public policies within their communities.
Physical Activity of Adolescents with and without Disabilities from a Complete Enumeration Study (n = 128,803): School Health Promotion Study 2017
Authors: Ng Kwok , Sainio Päivi , Sit Cindy
Published: August 2019

Evidence suggests that adolescent males take part in more moderate-to-vigorous physical activity (MVPA) than females, and that adolescents with disabilities participate in even less. Public health data are typically based on the international physical activity (PA) recommendations of at least 60 minutes of MVPA daily. However, it appears that data are lost because a person who reports MVPA 0–6 days a week is grouped together and is considered as ‘inactive’. Therefore, the purposes of this study were to report differences among adolescents with and without disabilities who were ‘active’ and ‘inactive’ and to explore differences by sex. A complete enumeration study (2017 School Health Promotion Survey; n = 128,803) of Finnish adolescents aged between 14–19 years old was conducted. The single item self-report MVPA was used with items from the Washington Group on Disability Statistics. Data were grouped into physiological and cognitive disabilities and were split into active and inactive adolescents based on the PA recommendations; subsequently, binary logistic regression analyses were performed. Data from the inactive participants were analyzed with multivariate analysis of covariance and effect sizes were reported. Approximately 10% of males and 17% of females reported disabilities. There were fewer adolescents with disabilities who took part in daily PA (OR = 0.90, CI = 0.85–0.94), especially among those with cognitive disabilities (OR = 0.86, CI = 0.82–0.91). There were more active male than female adolescents (OR = 1.48, CI = 1.43–1.52). Of the inactive adolescents, females reported similar MVPA to males, with and without disabilities after controlling for age, school type, and family financial situation. Inactive adolescents with walking difficulties reported the least amount of MVPA (males; mean = 2.24, CI = 2.03–2.44, females; mean = 2.18, CI = 1.99–2.37). The difference in means with adolescents without disabilities according to Cohen’s d effect size was medium for males (0.56) and females (0.58). The effect sizes from all other groups of disabilities were small. The difference in PA between males and females has diminished among the inactive groups, yet there is still a need to improve the gap between males and females, especially for those who meet the PA recommendations. More strategies are needed to improve MVPA among adolescents with disabilities, especially those with cognitive disabilities.
Who Are the Beneficiaries of China’s New Rural Pension Scheme? Sons, Daughters, or Parents?
Authors: Zhang Zhaohua , Luo Yuxi , Robinson Derrick
Published: August 2019

By applying a fuzzy regression discontinuity design, this study investigates whether sons, daughters, or parents are the beneficiaries of China’s New Rural Pension Scheme. Using data drawn from the China Health and Retirement Longitudinal Survey, our results indicate that pension income crowds out approximately 27.9% of the monetary support from adult sons and decreases the likelihood that adult sons live with their parents by 6.5%. However, we do not find a significant effect of pension income on the likelihood that adult daughters live with their parents. In regards to the well-being of parents, which is measured by consumption and health outcomes, the results show that pension income increases food and non-food consumption by 16.3 and 15.1%, respectively, and improves the psychological health of the elderly. Accounting for the different effects of pension income for those with different income levels, our results show that the New Rural Pension Scheme only has a significant effect on the poor elderly.
Methods and Application of Archeological Cloud Platform for Grand Sites Based on Spatio-Temporal Big Data
Authors: Wu Yongxing , Lin Shaofu , Peng Fei , Li Qi
Published: August 2019

Grand sites are important witnesses of human civilization. The archeology of grand sites has the characteristics of a long period, interdisciplinary study, irreversibility and uncertainties. Because of the lack of effective methods and valid tools, large amounts of archeological data cannot be properly processed in time, which creates many difficulties for the conservation and use of grand sites. This study provides a method of integrating spatio-temporal big data of grand sites, including classification and coding, spatial scales and a spatio-temporal framework, through which the integration of archeological data of multiple sites or different archeological excavations is realized. A system architecture was further proposed for an archeological information cloud platform for grand sites. By providing services such as data, visualization, standardizations, spatial analysis, and application software, the archeological information cloud platform of grand sites can display sites, ruins, and relics in 2D and 3D according to their correlation. It can also display the transformation of space and time around archeological cultures, and restored ruins in a 3D virtual environment. The platform provides increased support to interdisciplinary study and the dissemination of research results. Taking the Origin of Chinese Civilization Project as a case study, it shows that the method for data aggregation and fusion proposed in this study can efficiently integrate multi-source heterogeneous archeological spatio-temporal data of different sites or different periods. The archeological information cloud platform has great significance to the study of the origin of Chinese civilization, dissemination of Chinese civilization, and the public participation in archeology, which would promote the sustainable development of the conservation and use of grand sites.
Direction-Aware Continuous Moving K-Nearest-Neighbor Query in Road Networks
Authors: Dong Tianyang , Yuan Lulu , Shang Yuehui , Ye Yang , Zhang Ling
Published: August 2019

Continuous K-nearest neighbor (CKNN) queries on moving objects retrieve the K-nearest neighbors of all points along a query trajectory. They mainly deal with the moving objects that are nearest to the moving user within a specified period of time. The existing methods of CKNN queries often recommend K objects to users based on distance, but they do not consider the moving directions of objects in a road network. Although a few CKNN query methods consider the movement directions of moving objects in Euclidean space, no efficient direction determination algorithm has been applied to CKNN queries over data streams in spatial road networks until now. In order to find the top K-nearest objects move towards the query object within a period of time, this paper presents a novel algorithm of direction-aware continuous moving K-nearest neighbor (DACKNN) queries in road networks. In this method, the objects’ azimuth information is adopted to determine the moving direction, ensuring the moving objects in the result set towards the query object. In addition, we evaluate the DACKNN query algorithm via comprehensive tests on the Los Angeles network TIGER/LINE data and compare DACKNN with other existing algorithms. The comparative test results demonstrate that our algorithm can perform the direction-aware CKNN query accurately and efficiently.
Synovial Cytokines Significantly Correlate with Osteoarthritis-Related Knee Pain and Disability: Inflammatory Mediators of Potential Clinical Relevance
Authors: Nees Timo A. , Rosshirt Nils , Zhang Jiji A. , Reiner Tobias , Sorbi Reza , Tripel Elena , Walker Tilman , Schiltenwolf Marcus , Hagmann Sébastien , Moradi Babak
Published: August 2019

The aim of this study was to identify inflammatory mediators of potential clinical relevance in synovial fluid (SF) samples of patients with knee osteoarthritis (OA). Therefore, radiographic OA severity, knee pain and function of 34 OA patients undergoing unicompartmental (UC) and bicompartmental (BC) knee arthroplasty were assessed prior to surgery and SF samples were analyzed for a broad variety of inflammatory mediators, including interleukins (ILs), interferons (IFNs), C-X-C motif ligand chemokines (CXCLs), and growth factors (nerve growth factor; NGF, vascular endothelial growth factor; VEGF, and stem cell growth factor β; SCGF-β) using multiplex assay. Significant differences were observed between the SF levels of different inflammatory markers. When compared to UC OA, significantly higher concentrations of IL-7, IL-8, IL-10, IL-12, IL-13, IFN-γ, VEGF and CXCL1 were detected in BC OA. Correlation analyses revealed significant associations between OA severity and IL-6, IL-8, IFN-γ, SCGF-β, VEGF, CXCL1. Interestingly, increases in both anti- (IL-10, IL-13) and pro-inflammatory (IL-7, IL-12, IFN-γ) cytokines, as well as growth factors (SCGF-β, VEGF), correlated significantly with the level of knee pain. Poorer knee function was associated with higher IL-6, IL-10, IL-12, IL-13, IL-18, βNGF, SCGF-β, VEGF and CXCL9 levels. In conclusion, this study provides an extensive profile of synovial inflammatory mediators in knee OA and identifies cytokines of potential clinical relevance. In fact, five of the mediators examined (IL-10, IL-12, IL-13, SCGF-β, VEGF) significantly correlate with both knee pain and function.
Depth Selection and In Situ Validation for Offshore Mussel Aquaculture in Northeast United States Federal Waters
Authors: Mizuta Darien Danielle , Wikfors Gary H.
Published: August 2019

As mariculture progresses offshore in the US Exclusive Economic Zone, technical and ecological challenges need to be overcome, such as the choice of suitable sites that favor the production of target species. The offshore culture of blue mussels, Mytilus edulis, is performed with submerged longlines and mussels need to withstand more motion than on coastal sites. Temperature affects the ability of the byssus to adhere to farming rope, while chlorophyll concentration provides an estimation of food availability. Together, these are important factors in predicting the suitability of offshore mussel farms. To identify suitable depth of submersion for mussel ropes in New England federal waters, historical oceanographic data of temperature and chlorophyll a from 2005 to 2012 were used. The results suggest that mussel ropes were submerged during summer to a minimum depth of 15 m in northern and a 20-m depth in southern areas of New England where temperature is at a species-optimum and phytoplankton biomass is abundant. For the site offshore Massachusetts, in situ biodeposition measurements validated predicted depth, confirming satisfactory mussel performance. Promising local areas have shallow thermoclines, such as offshore Long Island, Cape Ann and New Hampshire. Recommended depths can be adjusted to future temperature increases associated with climate change.
Control Stimuli in Experimental Code-Switching Research
Authors: Koronkiewicz Bryan
Published: August 2019

The current study investigates whether there is variation among different types of control stimuli in code-switching (CS) research, how such stimuli can be used to accommodate heterogeneity, and how they can also be used as a baseline comparison of acceptability. A group of native Spanish–English bilinguals (n = 20) completed a written acceptability judgment task with a 7-point Likert scale. Five different types of control stimuli were included, with three types considered to be completely acceptable (complex-sentence switches, direct-object switches, and subject–predicate switches) and two types considered to be completely unacceptable (pronoun switches and present–perfect switches). Additionally, a set of present–progressive switches were included as a comparison, as their acceptability status is still actively debated. The participants as a whole exhibited the expected grammatical distinctions among the control stimuli, but with a high degree of individual variability. Pronoun switches and auxiliary verb switches were rated significantly lower than the complex-sentence switches, direct-object switches, and subject–predicate switches. These results show that control stimuli can also establish a baseline comparison of acceptability, and recommendations for inclusion in experimental CS research are provided.
The Effect of Thermocycling on Surface Layer Properties of Light Cured Polymer Matrix Ceramic Composites (PMCCs) Used in Sliding Friction Pair
Authors: Pieniak Daniel , Walczak Agata , Niewczas Agata M. , Przystupa Krzysztof
Published: August 2019

This paper discusses the problem of thermocycling effect of light-curing polymer–ceramic composites. Cyclic thermal shocks were simulated in laboratory conditions. As a rule, these loads were supposed to reproduce the actual conditions of biomaterials exploitation. Periodically variable stresses occurring in dental restorations are associated with the wear of cold and hot foods and beverages. They lead to changes in the properties of composites, including the properties of the surface layer. The aim of the work was to assess the impact of cyclic hydrothermal interactions on the properties of the surface layer of composites relevant to the operational quality. Two commercial materials manufactured by the world’s leading producer (3M ESPE)—Filtek Z550, Filtek Flow and two experimental, micro-hybrid and flow type composites marked Ex-mhyb(P) and Ex-flow(P), respectively. All tests were carried out before and after hydro-thermal cycles (flowing water thermocycling). Micro-hardness test using the Vickers method, indentation hardness, and resistance to tribological wear in a ball–disc system in sliding friction conditions were performed. In addition, observations of the surface layer of composites on the SEM (scanning electron microscope) were carried out. It was noticed that semi-liquid composites, containing a smaller amount of filler, retain higher stability of mechanical and tribological properties of the surface layer under cyclic hydro-thermal loads. Coefficient of friction of samples after hydro-thermal cycles increased for micro-hybrid materials and Filtek Flow (FFlow) composite. In the case of Ex-flow(P) material, the coefficient of friction decreased. The microhardness of composites also changed, the variability of this size depended on the type of material. Composites with a higher content of filler particles were characterized by greater variability of microhardness under the influence of thermocycles. The resistance to tribological wear also changed in a similar way. Composites containing higher volume fraction of inorganic filler showed higher tribological wear after thermocycling. The wear resistance of flow composites changed to a lesser extent, after thermocycling increased. The paper also showed that, in real kinematic nodes, the surface layer of light-curing ceramic–polymer composites is exposed to significant non-tribological (erosive, thermal, and chemical) defects that synergize with tribological ones. In slip pairs loaded dynamically, under mixed friction conditions, tribological wear of PMCCs (polymer matrix ceramic composites) is manifested by spalling (spalling of the material flakes, in particular the polymer phase) and pitting (crushing wear caused by wear products, in particular large filler particles or clusters, previously adhesively extracted).
Mechanochemistry of Metal Hydrides: Recent Advances
Authors: Huot Jacques , Cuevas Fermín , Deledda Stefano , Edalati Kaveh , Filinchuk Yaroslav , Grosdidier Thierry , Hauback Bjørn C. , Heere Michael , Jensen Torben R. , Latroche Michel , Sartori Sabrina
Published: August 2019

This paper is a collection of selected contributions of the 1st International Workshop on Mechanochemistry of Metal Hydrides that was held in Oslo in May 2018. In this paper, the recent developments in the use of mechanochemistry to synthesize and modify metal hydrides are reviewed. A special emphasis is made on new techniques beside the traditional way of ball milling. High energy milling, ball milling under hydrogen reactive gas, cryomilling and severe plastic deformation techniques such as High-Pressure Torsion (HPT), Surface Mechanical Attrition Treatment (SMAT) and cold rolling are discussed. The new characterization method of in-situ X-ray diffraction during milling is described.
Experimental Investigation of a Slip in High-Performance Steel-Concrete Small Box Girder with Different Combinations of Group Studs
Authors: Gautam Bishnu Gupt , Xiang Yiqiang , Liao Xiaohui , Qiu Zheng , Guo Shuhai
Published: August 2019

Due to the significant advantages of steel-concrete composite beams, they are widely used for accelerated bridge construction (ABC). However, there is still a lack of experimental research on the proper design of ABC, especially in the slip with a different group of shear connectors. As a component of steel-concrete composite structure, shear studs play a vital role in the performance of composite structures. This paper investigates the influence of group studs in simply supported and continuous box girders. To this end, three sets of simply supported steel-concrete composite small box girders and two continuous steel-concrete composite small box girders were made with different groups of shear studs, and the slip generated along the beams was recorded under different caseloads. The results were then compared with the proposed simplified equations. The results show that the slip value of the test beam is inversely proportional to the degree of shear connection. The slip of Simply Supported Prefabricated Beam-3 (SPB3) is 1.247 times more than Simply Supported Prefabricated Beam-1 (SPB1), and 2.023 times more than Simply Supported Prifabricated Beam-2 (SPB2). Also, the slip value of Experimental Continuous Beam-1 (ECB1) is 1.952 times more than Experimental Continuous Beam-2 (ECB2). The higher the degree of shear connection, the smaller the maximum slip value.
Non-Rectangular Dynamic Range of the Drive System: A New Approach for the Choice of Motor and Transmission
Authors: Cusimano Giancarlo
Published: August 2019

This paper deals with the choice of the motor-transmission couple to drive a joint in the frequent case in which the limit curve of the dynamic operating range of the drive system depends on the motor speed. The paper considers a given drive system and proposes a method that resorts to a succession of instant analyses during the reference task: for a transmission with no energy dissipation the result, if it exists, is a range of transmission ratios that can be coupled with the given motor in order to perform the reference task. The extension of the method to a real transmission is a diagram that correlates the transmission ratio and the direct and inverse efficiency of the reducer and that offers the designer an overview of the transmissions that can be coupled with the given motor to perform the reference task.
More Buildings Make More Generalizable Models—Benchmarking Prediction Methods on Open Electrical Meter Data
Authors: Miller Clayton
Published: August 2019

Prediction is a common machine learning (ML) technique used on building energy consumption data. This process is valuable for anomaly detection, load profile-based building control and measurement and verification procedures. Hundreds of building energy prediction techniques have been developed over the last three decades, yet there is still no consensus on which techniques are the most effective for various building types. In addition, many of the techniques developed are not publicly available to the general research community. This paper outlines a library of open-source regression techniques from the Scikit-Learn Python library and describes the process of applying them to open hourly electrical meter data from 482 non-residential buildings from the Building Data Genome Project. The results illustrate that there are several techniques, notably decision tree-based models, that perform well on two-thirds of the total cohort of buildings. However, over one-third of the buildings, specifically primary schools, performed poorly. This example implementation shows that there is no one size-fits-all modeling solution and that various types of temporal behavior are difficult to capture using machine learning. An analysis of the generalizability of the models tested motivates the need for the application of future techniques to a board range of building types and behaviors. The importance of this type of scalability analysis is discussed in the context of the growth of energy meter and other Internet-of-Things (IoT) data streams in the built environment. This framework is designed to be an example baseline implementation for other building energy data prediction methods as applied to a larger population of buildings. For reproducibility, the entire code base and data sets are found on Github.
Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA
Authors: Finol-Urdaneta Rocio K. , McArthur Jeffrey R. , Korkosh Vyacheslav S. , Huang Sun , McMaster Denis , Glavica Robert , Tikhonov Denis B. , Zhorov Boris S. , French Robert J.
Published: August 2019

µ-Conotoxin PIIIA, in the sub-picomolar, range inhibits the archetypal bacterial sodium channel NaChBac (NavBh) in a voltage- and use-dependent manner. Peptide µ-conotoxins were first recognized as potent components of the venoms of fish-hunting cone snails that selectively inhibit voltage-gated skeletal muscle sodium channels, thus preventing muscle contraction. Intriguingly, computer simulations predicted that PIIIA binds to prokaryotic channel NavAb with much higher affinity than to fish (and other vertebrates) skeletal muscle sodium channel (Nav 1.4). Here, using whole-cell voltage clamp, we demonstrate that PIIIA inhibits NavBac mediated currents even more potently than predicted. From concentration-response data, with [PIIIA] varying more than 6 orders of magnitude (10−12 to 10−5 M), we estimated an IC50 = ~5 pM, maximal block of 0.95 and a Hill coefficient of 0.81 for the inhibition of peak currents. Inhibition was stronger at depolarized holding potentials and was modulated by the frequency and duration of the stimulation pulses. An important feature of the PIIIA action was acceleration of macroscopic inactivation. Docking of PIIIA in a NaChBac (NavBh) model revealed two interconvertible binding modes. In one mode, PIIIA sterically and electrostatically blocks the permeation pathway. In a second mode, apparent stabilization of the inactivated state was achieved by PIIIA binding between P2 helices and trans-membrane S5s from adjacent channel subunits, partially occluding the outer pore. Together, our experimental and computational results suggest that, besides blocking the channel-mediated currents by directly occluding the conducting pathway, PIIIA may also change the relative populations of conducting (activated) and non-conducting (inactivated) states.
Can Visceral Adiposity Index Serve as a Simple Tool for Identifying Individuals with Insulin Resistance in Daily Clinical Practice?
Authors: Štěpánek Ladislav , Horáková Dagmar , Cibičková Ľubica , Vaverková Helena , Karásek David , Nakládalová Marie , Zapletalová Jana
Published: August 2019

Background and objectives: The visceral adiposity index (VAI), estimating visceral adiposity dysfunction through a simple formula, could serve as a useful tool for identifying individuals at higher cardiometabolic risk. Its relationship with insulin resistance (IR), assessed using the homeostasis model assessment of IR (HOMA-IR), and metabolic syndrome (MetS) components remains unclear. The study aimed to investigate the association of VAI with both HOMA-IR and MetS. Materials and Methods: After undergoing anthropometric and biochemical studies, 783 individuals were divided into three groups according to a number of present MetS components. The VAI cut-offs signaling MetS and HOMA-IR were determined by maximizing the sum of the sensitivity and specificity. Correlation analysis was performed to explore the associations between VAI and other tested parameters. A logistic stepwise regression analysis was applied to identify statistically significant determinants of HOMA-IR. Given the variability of reference values, two thresholds of HOMA-IR were applied, namely 2.0 and 3.8. Results: VAI increased significantly between the groups with a rising number of MetS components. The VAI cut-off for MetS was 2.37, with a sensitivity of 0.86 and a specificity of 0.78. The same cut-off point identified subjects with HOMA-IR = 3.8, with a sensitivity of 0.79 and a specificity of 0.66. The VAI cut-off for HOMA-IR = 2.0 was 1.89, with a sensitivity of 0.74 and a specificity of 0.68. The strongest correlations of VAI were noted with HOMA-IR (r = 0.51) and insulin (r = 0.49), respectively, while the strongest correlation of HOMA-IR was with waist circumference (r = 0.54). Not one of the routine parameters was a significant predictor in the regression analysis. Conclusions: The obtained results show an existing association of VAI with HOMA-IR. The high sensitivity and specificity of the cut-offs may allow the application of VAI in common clinical practice.