bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Efficacy of Tofacitinib versus Betamethasone Pulse Therapy in the Treatment of Vitiligo
Authors: Shafquat Hira , Ahmed Hafiz Bashir , Memon Abeer , Shah Madiha , Memon Nazish , Khan Bedar Bakhat
Published: December 2024

Vitiligo is a chronic autoimmune skin disorder characterized by depigmentation due to melanocyte destruction, significantly impacting patients' quality of life. Emerging treatments, including Janus kinase inhibitors like tofacitinib, offer promising alternatives to conventional therapies such as corticosteroids. Objective: To compare the efficacy of tofacitinib with betamethasone pulse therapy in achieving re-pigmentation in vitiligo patients. Methods: This quasi experimental study was conducted on 42 patients of vitiligo of either gender with ages between 12 and 65 years and had a history of vitiligo for over one year with a body surface area affected by vitiligo exceeding 5%, and a vitiligo area scoring index score of more than 10 were included in the study. Patients were divided into 2 equal groups using alternate assignments. Group A were treated with betamethasone pulseerapy of 4mg twice a week. Group B were treated with tofacitinib at a dose of 5 mg twice a day. Results: Optimal recovery (vitiligo area scoring index decrease ≥20% from baseline) was observed in 14 (66.7%) of the tofacitinib group compared to 6 (28.6%) in the betamethasone group, highlighting tofacitinib’s superior efficacy in achieving significant vitiligo area scoring index reduction. Over three months, the BSA affected by vitiligo decreased in both groups, with a significantly greater reduction in Group B (tofacitinib) compared to Group A (betamethasone). Conclusions: It was concluded that tofacitinib may be more effective than betamethasone pulse therapy in reducing both the extent and severity of vitiligo.
“Arheološka istraživanja” Tome Dragičevića u sjeveroistočnoj Bosni / “Archaeological research” by Tomo Dragičević in Northeastern Bosnia
Authors: Mujkanović Ago
Published: December 2024

The paper presents an overview of archaeological research in Northeastern Bosnia, conducted by the ordnance sergeant Tomo Dragičević, which is poorly known in today’s science. This paper contains data on the aforementioned research, discoveries, and conclusions reached by scientists of the time. The data presented in this paper were mainly collected from the Austro-Hungarian press, scientific journals, and archival sources. The aim of this research was to collect data based on archival sources, analyze the data, systematize them, and present them to the scientific public. This paper presents archaeological research in northeastern Bosnia that has been poorly known to date. One of the first researchers we know of who showed interest in antiquities and archaeological sites was the ordnance sergeant Tomo Dragičević. The review of Tomo Dragičević’s archaeological research is presented in chronological order, as presented in scientific journals.
THÚC ĐẨY PHÁT TRIỂN KINH TẾ TƯ NHÂN TRONG NÔNG NGHIỆP Ở VIỆT NAM THỜI KỲ HỘI NHẬP QUỐC TẾ
Authors: Nhung Nguyễn Thị Hồng
Published: December 2024

Kinh tế tư nhân ngày càng phát triển và trở thành lực lượng quan trọng, có nhiều đóng góp trong công cuộc đổi mới và hội nhập quốc tế của Việt Nam. Để nông nghiệp Việt Nam phát triển vững mạnh, có khả năng cạnh tranh trên trường quốc tế, kinh tế tư nhân trở thành yếu tố then chốt, đóng vai trò hạt nhân. Kinh tế tư nhân góp phần đẩy mạnh tái cơ cấu nền nông nghiệp đất nước, tham gia mô hình liên kết để tạo chuỗi giá trị nông sản. Tuy nhiên, kinh tế tư nhân trong nông nghiệp ở Việt Nam phát triển chậm do nhiều yếu tố khách quan và chủ quan. Từ thực trạng phát triển kinh tế tư nhân trong nông nghiệp, bài viết khuyến nghị sáu giải pháp thúc đẩy phát triển kinh tế tư nhân trong nông nghiệp ở Việt Nam thời kỳ hội nhập quốc tế.Từ khóa: hội nhập quốc tế, kinh tế tư nhân, nông nghiệp, Việt Nam.
DIỄN NGÔN VỀ NGƯỜI PHỤ NỮ TRONG SÔNG CÔN MÙA LŨ CỦA NGUYỄN MỘNG GIÁC TỪ ĐIỂM NHÌN ĐỊNH GIỚI
Authors: Tịnh Thy Nguyễn Thị
Published: December 2024

Trong tiểu thuyết Sông Côn mùa lũ của Nguyễn Mộng Giác, người phụ nữ với nhiều thành phần, nhiều lứa tuổi, nhiều tính cách và số phận khác biệt đã được xây dựng nên bằng điểm nhìn định giới. Dựa trên khung lý thuyết về giới được trình bày trong cuốn sách Khái niệm then chốt trong nghiên cứu giới, bài báo này phân tích điểm nhìn định giới qua ba nội dung chính sau: điểm nhìn định giới phủ nhận vai trò lịch sử của người phụ nữ, khẳng định người phụ nữ là nạn nhân của lịch sử, vai trò của định giới trong việc xây dựng tính cách nhân vật. Nghiên cứu này sử dụng kết hợp các phương pháp lịch sử, cấu trúc - hệ thống và liên ngành. Thông qua phân tích này, bài báo hướng đến nhận diện diễn ngôn về người phụ nữ của Sông Côn mùa lũ, qua đó xác định tư tưởng và nghệ thuật sáng tác của nhà văn.
PENARAPAN PENGURANGAN HUKUMAN TINDAK PIDANA BERDASARKAN RESTORATIF JUSTICE MENURUT PERMA NOMOR 1 TAHUN 2024
Authors: Agus Sugiyatmo  , Ermania Widjajanti
Published: December 2024

Restorative Justice bertujuan untuk mengubah paradigma penegakan hukum yang lebih berfokus pada pemulihan daripada hukuman. Restorative dalam pidana adalah upaya terakhir (ultimum remedium). Restorative Justice sebenarnya sudah diterapkan pada jaman nenek moyang kita yang orang timur dengan penyelesaikan masalah dengan musyawarah mufakat. Perkembangan Restorative justice di Indonesia secara formal muncul dalam sistem hukum Indonesia melalui Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak (UU SPPA), yang menekankan pada pengalihan proses peradilan pidana ke proses diluar peradilan pidana (diversi) untuk anak yang berhadapan dengan hukum. Lalu berkembang berbagai peraturan dan kebijakan di tahap penyidikan di Kepolisian dengan Peraturan Polri Nomor 8 Tahun, tahap penuntutan di Kejaksaan dengan Peraturan Kejaksaan Nomor 15 Tahun 2020, dan ditahap Pengadilan di Mahkamah Agung dengan Peraturan Mahkamah Agung Nomor 1 Tahun 2024. Masing – masing peraturan internal lembaga tersebut dengan UU Nomor 1 Tahun 2023 (KUHP Baru) sebagai aturan yang lebih tinggi, dengan harapan adanya pemetaan peraturan – peraturan tersebut dapat diketahui perlunya penyesuaian atau pencabutan peraturan tersebut dengan adanya KUHP Baru. Ke depannya hasil asesmen tersebut dapat berkontribusi sebagai masukan dalam penyusunan revisi Undang – Undang  Nomor 8 Tahun 1981 tentang Hukum Acara Pidana (KUHAP).
MODEL ARIMA BOX-JENKINS UNTUK PERAMALAN PERGERAKAN HARGA SAHAM PT. ASTRA INTERNATIONAL TBK
Authors: Shalahuddin M. , Oktaviyani Henny
Published: December 2024

Peramalan harga saham merupakan salah satu aspek yang penting dalam analisis keuangan dikarenakan berperan penting bagi investor dalam membuat strategi investasinya. Ketepatan dalam memprediksi harga saham tidak hanya membantu investor dalam mengoptimalkan keuntungan yang didapatkan tetapi juga membantu investor dalam meminimalkan risiko kerugiannya. Penelitian ini bertujuan untuk menentukan model yang paling akurat dalam meramalkan harga saham penutupan PT. Astra International Tbk menggunakan pendekatan Box-Jenkins ARIMA (Autoregressive Integrated Moving Average). Data yang digunakan berupa data kuantitatif harga saham penutupan bulanan PT. Astra International Tbk dari Juli 2009 hingga Juni 2024, yang diolah menggunakan perangkat lunak Minitab. Hasil analisis menunjukkan bahwa model terbaik adalah ARIMA (1,1,1), yang terdiri dari komponen AR orde 1, MA orde 1, dan satu kali proses differencing. Model ARIMA (1,1,1) terbukti memenuhi kriteria signifikansi pada setiap komponennya dan memiliki residual yang bersifat white noise atau acak.
Digital production and new media convergence publishing practice of scientific and technological periodicals based on XML integration: The case of Acta Scientiae Circumstantiae
Authors: Yang Guihua , Bu Qingjie , Wang Hu , Li Yonghuan
Published: December 2024

Background: This study aims to systematically summarize the advantages of using a digital publishing platform for scientific and technological journals based on extensible markup language (XML)-integrated production. It also seeks to analyze the effects of the fusion of digital production and new media practices in order to provide a reference for China's digital publication of scientific and technological journals and its combination with new media. Methods: Taking Acta Scientiae Circumstantiae as an example, this study builds a model of digital production and new media fusion publishing for scientific and technological journals based on XML integration by reviewing the shortcomings of traditional production models. The advantages and practical applications of digital production and new media fusion publishing are analyzed. Results: The adoption of an XML-integrated production platform results in producing content once and its diverse publication. Single articles or entire issues can be quickly released, allowing these to be immediately published four months ahead of the network first release and thus shortening the publication cycle. The platform is seamlessly connected with journal websites and WeChat, achieving simultaneous priority publication and full-issue publication on the PC and mobile ends and realizing media convergence and multichannel dissemination. During the initial period, the average downloads per article significantly increased, with single-article downloads reaching 1961 times. Conclusion: Using an XML-integrated production platform can optimize the publishing process, improve the level of digitalization, and increase work efficiency. It helps shorten the publication cycle, accelerate the speed of dissemination, and enhance the academic influence of a journal.
A one-stop solution for generating, inserting, and verifying quick response codes in scientific journals based on Python
Authors: Niu Xinyue , Qi Lijuan , Fang Mei
Published: December 2024

Background: This study aims to make quick response (QR) code processing operable, reliable, and efficient. It discusses the exploration and practice of QR code processing in Computer Systems & Applications, providing a useful reference for editors. Methods: Common problems encountered when manually handling QR codes are summarized and analyzed. A QR code-integrated tool is designed using Python language to propose an integrated solution for QR codes, and the tool is compared with manual solutions. Results: The self-developed QR code-integrated tool can realize the automatic processing of tasks, such as generating, inserting, and verifying QR codes, thereby achieving high efficiency and reliability. For example, it takes about 2 hours to handle 45 papers by hand, whereas automated operations require only about 30 seconds, without any errors. The use of tools to automatically verify QR codes no longer relies on uniform resource locator (URL) activation, achieving perfect integration between QR code processing flow and the traditional editorial publishing process. Conclusion: Using Python, this study demonstrates that high-quality QR code settings can be achieved efficiently in single articles in scientific journals. Computer automation operations have high efficiency and strong reliability in dealing with repetitive work. Scientific journal editors should think creatively and continuously improve their work efficiency by adopting computer technology to refine workflow.
Technical skills talent development in a vocational undergraduate program: Case study of a modern communication engineering program
Authors: Wang Yongxue , Wu Weiqiang , Wang Sunan
Published: December 2024

The development of the digital economy represents a strategic decision aimed at addressing the demands of the current scientific and technological revolution and industrial transformation. Vocational undergraduate programs in modern communication engineering play a crucial role in developing high-level technical talent within the information and communication sector to bolster the advancement of the digital economy. This necessitates the delineation of talent development objectives, the methodical formulation of talent training schemes, investigations into synergistic models of industry-education integration, and the establishment of the professional attributes characteristic of vocational undergraduate education. Using the Modern Communication Engineering program at Shenzhen Polytechnic University as a case study, we describe a talent cultivation model and practical experiences within the field of modern communication engineering. This model encompasses the technology-driven, project-based and competency-based integration of practice and experience within a comprehensive curriculum and professional certification system and offers insights into the furtherance of high-quality vocational undergraduate education in modern communication engineering.
Sino-German cooperation in vocational teacher training: A macro-micro-macro analysis of good intentions and unintended outcomes in China
Authors: Cao Wenyu , Schmees Johannes Karl , Li Jun , Grunau Janika
Published: December 2024

In this paper, we use the exemplary case of Sino-German cooperation to develop teacher training for technical and vocational education and training (TVET) in order to demonstrate both incongruent understandings of TVET systems in intercontinental cooperation and missing links between macrolevel objectives and micro level actions. To illustrate these problems, we use Coleman's boat model. Using this model, we conceptualize the objectives of an intercontinental cooperation project for TVET teacher training at the macrolevel and contrast these objectives with four different student types (enterprise-oriented students, TVET researcher-oriented students, TVET teacher-avoiding students, and TVET teacher-oriented students) who used their opportunities within this project to enhance their own educational endeavors. These endeavors were not necessarily in line with the objectives and eventually caused the termination of the undergraduate TVET teacher training program. As a result, only students of the fourth type decided to become TVET teachers, but mostly at the tertiary level in higher TVET colleges. Reasons for choosing a different career path include the attractiveness of other professional fields. For the TVET teacher training, we therefore recommend curricular modifications and raising students' awareness of the importance of TVET and its teachers in society.
The evolution of vocational education colleges and institutes in Canada: An analysis of trends and challenges
Authors: Jones Glen A.
Published: December 2024

Canada has placed a strong emphasis on the provision of vocational and technical education, and this paper provides an overview and critical analysis of the development, trends and challenges associated with the public colleges and institutes sector, as well as private career colleges. Under Canada's federal arrangements, postsecondary education is the responsibility of the provinces, and each province and territory has created a somewhat unique system. This paper provides a review of the development of vocational and technical education colleges, both public colleges established by governments and private career colleges established by private industry, drawing on the existing research literature. Common trends are discussed, such as a transition in credentials offered by colleges, including degrees in some provinces, a focus on student pathways and mobility within postsecondary systems, increasing international student enrolment as a source of revenue generation, expanding roles in applied research, and the emergence in some provinces of self-governing Indigenous institutes serving the needs of Indigenous communities. A core conclusion emerging from this analysis is that the traditional boundaries that have separated the public university and college sectors have been blurring in response to shifting labour market and student demands.
Screening signals or capability enhancement: The educational effect on the starting salary of engineering master's graduates
Authors: Guo Hui , Liu Lusen , Wang Chunxiao
Published: December 2024

The employment of college graduates has become a pressing social concern. Based on classical human capital theory and screening theory, this study analyzes the effects of human capital and educational background on the starting salary of engineering master's graduates. Educational background and hard engineering skills were found to have a distinct salary effect on engineering master's students; however, the salary effect of educational background was not based on the promotion of human capital development and exhibited clear characteristics of institution and specialty screening. Moreover, significant disparities exist between factors affecting starting salaries in engineering versus nonengineering roles. To enhance the attractiveness and quality of engineering master's programs, it is crucial to promote a diversified higher education system and develop market-driven talent cultivation models.
Pemetaan Sumber Daya Lokal Kota Pekalongan untuk Mendukung Kebutuhan Kawasan Industri Terpadu Batang
Authors: Musyarofah Siti Afiani , Tontowi Alva Edy
Published: December 2024

Berdirinya Kawasan Industri Terpadu Batang (KITB) membuka peluang ekonomi dengan menyerap tenaga kerja dan memenuhi kebutuhan berbasis sumber daya lokal. Kota Pekalongan yang berbatasan dengan KITB berpeluang memperoleh keuntungan finansial dan sosial, mengurangi ketimpangan pembangunan daerah, serta meningkatkan Pendapatan Asli Daerah (PAD). Namun, Kota Pekalongan belum memiliki peta potensi sumber daya yang komprehensif sesuai kebutuhan KITB. Penelitian ini bertujuan untuk membangun peta potensi Sumber Daya Kota Pekalongan yang lebih komprehensif sesuai kebutuhan KITB. Analisis kualitatif deskriptif digunakan untuk menganalisis multiplier effect KITB dan pemetaan sosial untuk pemetaan sumber daya manusia sesuai kebutuhan KITB. Sementara itu, analisis kuantitatif dengan shift-share dan location quotient digunakan untuk analisis ekonominya. Terakhir, dilakukan analisis SWOT untuk mendeskripsikan strategi pengembangan potensi sumber daya lokal di Kota Pekalongan. Hasil penelitian menunjukkan bahwa terdapat empat (4) sektor unggulan dan potensial untuk dikembangkan sebagai penggerak perekonomian di Kota Pekalongan, yaitu: (1) Penyediaan akomodasi dan makan minum; (2) Penyediaan air bersih; Pengelolaan sampah, limbah, dan daur ulang; (3) Konstruksi; dan (4) Pelayanan kesehatan dan kegiatan sosial. Berdasarkan hasil analisis dampak pengganda, terdapat 10 sektor usaha di Kota Pekalongan yang sangat erat kaitannya dengan kebutuhan KITB, seperti industri pengolahan, industri kreatif, penyediaan akomodasi serta makan minuman, dan lain-lain. Sebanyak 56,89% dari angkatan kerja yang menganggur terbuka di Kota Pekalongan berpeluang untuk diserap menjadi tenaga kerja di berbagai tenant industri KITB dan dengan keterampilan yang dimilikinya dan telah disesuaikan dengan kebutuhan di 18 perusahaan, yaitu: keterampilan menjahit/garmen, informatika, konstruksi, dan pengelasan. Selain itu, beberapa strategi yang diusulkan Pemerintah Kota Pekalongan untuk mengembangkan potensi sumber daya lokal.
Sosyal Bilimlerde Araştırma Etiği
Authors: Dolanbay Hacer
Published: December 2024

Bilim, düşünce ve deneyler ile merak edilen bilinmezlikleri sistematik biçimde araştırma sürecidir. Bir problemin ortaya konularak bilimsel yöntemlerle incelenmesi ve değerlendirilmesi sürecini ifade eden bilimsel araştırmada bilim insanlarının belirli kurallara uyması gerekmektedir. Bu çalışmanın amacı sosyal bilimlerde araştırma etiği hakkında bilgi sunmaktır. Bu amaç doğrultusunda ulusal ve uluslararası literatür taranmış ve bölümler oluşturulmuştur. Araştırmada nitel araştırma yöntemlerinden doküman analizi yöntemi kullanılmıştır. Bu bağlamda var olan, araştırma konusu hakkında diğer kişi ya da kurumlar tarafından yazılmış belgeler incelenerek veriler elde edilmiştir. Bu bağlamda öncelikle etik ve bilim etiği kavramları açıklanarak bilim etiğinin tarihçesi hakkında bilgi verilmiştir. Sonrasında bilimsel araştırmalarda katılımcılar, araştırma süreci ve sonucu, araştırmacılarla ilgili, yazarlarla ilgili, yayınla ve araştırmaların değerlendirilesiyle ilgili uyulması gereken etik kurallar açıklanmıştır. Çalışmanın sonunda sosyal bilimlerde bilimsel etikle ilgili sorunların çözümü için bazı öneriler sunulmuştur.
Art Nouveau’nun Psikedelik Afişler Üzerindeki Etkisi ve Güncel Çalışmalara Yansımaları
Authors: Dinçer Sebahat Gökçen
Published: December 2024

Sanat akımlarının geçmişten günümüze kadar birbirlerini etkilemesi tarih boyunca sanatta yeni düşünce biçimlerinin ve görsel etkilerin doğmasına sebep olmuştur. Sanat akımlarının sınırlarının bulanıklaşmasıyla daha zengin bir estetik anlayış gelişmiştir. Akımların felsefi görüşleri ve biçimsel özellikleri sanatın çeşitlenmesine, işlevsel hale gelmesi ise tasarımın sanattan ayrışmasına zemin oluşturmuştur. Özellikle bu ayrışmada Art Nouveau önemli bir rol oynamış ve birçok sanat akımını derinden etkilemiştir. Etkisi altında kalan sanat akımları arasında psikedelik sanat da yer almaktadır. Art Nouveau’da görülen ideoloji ve biçimsel özelliklerin psikedelik estetikte yeniden görülmesi bu çalışmanın temelini oluşturmaktadır. Tarihsel bir inceleme niteliğinde olan bu çalışma, Art Nouveau etkisinin iz düşümlerini açığa çıkarırken diğer bir yandan akımlar arasındaki benzerliklerin günümüz tasarımlarına etkisini göstermeyi amaçlamaktadır. Bu bağlamda geçmişten ve günümüzden tasarımcıların çalışmaları mercek altına alınmıştır.
1960’lı Yıllarda Türk Sinema Dergilerinin Yayımlanma Motivasyonları Üzerine Bir İnceleme: Niçin Çıkıyoruz?
Authors: Yılmaz Muzaffer Musab
Published: December 2024

Türk sinema tarihi içerisinde 1960’lı yılların önemli bir yeri vardır. Bu dönemde üretilen film sayısı artmış ve seyirci ile güçlü bir bağ kurulmuştur. Sinema alanı ile doğru orantılı bir biçimde sinema yayıncılığı alanı da bu dönemde oldukça hareketli ve çok seslidir. Popüler bir kitle yayıncılığını takip eden dergilerin yanında Türk ve dünya sineması üzerine teorik bir perspektif çizen dergiler de hayat bulmuştur. Bu çalışmada, 1960'lı yıllarda yayın hayatına başlayan sinema dergilerinin çıkış motivasyonları incelenmiştir. Bu doğrultuda 1960’lı yıllarda sinema yayıncılığı alanına dahil olan 43 adet sinema dergisi belirlenmiştir ve bu dergilerin sunuş yazıları içerik analizi yöntemiyle ele alınmıştır. Sunuş yazılarında derginin neden kurulduğu ve temelde neyin amaçlandığı türünden bilgilerin yanında Türk sinemasına yönelik tutuma dair de bilgiler elde edilebilmektedir. Çalışmanın sonucunda, dönemin sinema dergileri ortamının çok sesli olduğu görülmüştür. Türk sinemasının büyüyen ve seyircisi ile güçlü bağlar kuran ulusal bir sinema olmasından dolayı entelektüel düzlemde onunla yüzleşme ya da onun gelişimine katkı sunma amaçlarının var olduğu görülmüştür. Film şirketleri, işletmeciler ve sinema derneklerinin de kendi faaliyetlerini ve sinemasal görüşlerini paylaşma ihtiyacı duyduğu ortaya çıkarılmıştır. Ayrıca, bu dönemde çıkan çok sayıda kitle dergisinin de seyircinin popüler film ve oyuncuları daha yakından tanıma ihtiyacını giderme amacıyla yayın hayatına dahil olduğu görülmüştür.
MCE CHATBOT-AI
Authors:   Computer Science And Engineering Malnad College Of Engineering,Hassan,Karnataka, DEEPTHI J. , V HEMASRI , V LEKHA , ML MAYURA
Published: December 2024

The Malnad College of Engineering Chat-Bot is an innovative application of Artificial Intelligence (AI) aimed at enhancing the communication between students, faculty, and staff within the college ecosystem. Designed to assist users with a wide array of queries ranging from academic information to administrative procedures, the chatbot uses Natural Language Processing (NLP) techniques to deliver accurate and efficient responses. The system was developed to improve accessibility, streamline student services, and reduce human intervention in routine inquiries, offering an interactive and user-friendly platform that supports the college's goal of digital transformation. This paper discusses the architecture, features, and implementation of the chatbot, along with its potential benefits and challenges, highlighting its role in revolutionizing the student experience at Malnad College of Engineering.

Index Terms
Artificial Intelligence (AI), Natural Language Processing (NLP), Chatbot, Machine Learning (ML), Educational Technology, College Chatbot, Student Services Automation, Digital Transformation, Context-Aware Conversations, Data Privacy, User Experience, Multilingual Support, Voice Recognition, Modular Design, Real-Time Responses.
Deep crop care: advanced Ai for loss prevention in cash crops
Authors:   Presidency School of Computer Science and Engineering Presidency University Bengaluru, Karnataka , India, Pattanashetti  Pallavi , A H  Keerthi , C S Manasa , M Nagarathna , K Marimuthu
Published: December 2024

Agriculture is vital to the Indian economy, with cash crops playing a significant role in rural income. Farmers face challenges such as pest infestations, crop diseases, and climate unpredictability, resulting in severe financial losses. This study introduces an integrated platform leveraging machine learning (ML), image processing, and web-based technologies to mitigate these issues. Modules include disease detection using Convolutional Neural Networks (CNN), crop yield prediction with Random Forest, and fertilizer recommendations using soil health parameters. These modules are integrated into a Django/flask-based web application, offering a user-friendly interface. Results demonstrate high accuracy and scalability, providing actionable insights to empower farmers. This initiative addresses agricultural challenges through data-driven solutions, promoting sustainable farming practices and improved productivity.

Keywords: Agriculture, Machine Learning, Crop Yield Prediction, plant disease Detection, Fertilizer Recommendation, Sustainable Farming
ANALISIS JENIS KERUSAKAN DAN PENANGANAN RUAS JALAN DESA PELING LALOMO BERDASARKAN METODE SURFACE DISTRES INDEX (SDI)
Authors: Lutfie Mukhtar , Fatahuddin Suriyati
Published: December 2024

Ruas jalan Desa Peling Lalomo merupakan salah satu jalan yang menggunakan perkerasan lentur sebagai penopang beban lalu lintas. Studi terhadap kondisi jalan diperlukan sebelum dilakukan perawatan, perbaikan dan rekonstruksi. Metode yang digunakan meliputi pengumpulan dan pengolahan data kerusakan jalan secara kuantitatif.  Penelitian ini bertujuan untuk mengetahui jenis kerusakan dan penanganan pada ruas jalan Desa Peling Lalomo dengan mengkaji jenis dan luas kerusakan berdasarkan metode SDI. Pelaksanaan penelitian ini meliputi menilai kondisi perkerasan secara visual dengan metode SDI dengan membagi ruas jalan 100 m per segmen sepanjang 2.000 meter, lebar perkerasan jalan 4,6 m. Hasil penelitian ini mengetahui jenis kerusakan yang terjadi pada jalan yaitu retak, lubang, dan bekas roda. Jenis kerusakan terbesar adalah retak dan lubang. Dari data yang diperoleh, memperlihatkan ruas Jalan Desa Peling Lalomo Kecamatan Buko Kabupaten Banggai Sulawesi Tengah Khususnya di segmen 10 mempunyai kondisi rusak berat, yaitu retak, lubang, dan bekas roda. Nilai SDI rata-rata dan kondisi permukaan yang terdapat pada ruas jalan Desa Peling Lalomo sebesar 207 dengan kondisi permukaan rusak berat. Persentase kondisi permukaan jalan rusak berat 85% dan rusak sedang 15%. Dari hasil perhitungan nilai SDI memperlihatkan bahwa jenis penanganan jalan Desa Peling Lalomo termasuk dalam program rekonstruksi jalan bagi kondisi jalan rusak berat dan pemeliharaan berkala bagi kondisi jalan rusak sedang.
Phytochemical and anti-oxidant properties of Pandanus odorifer of Andaman and Nicobar Islands
Authors:   Division of Natural Resource Management, ICAR-Central Island Agricultural Research Institute, Port Blair, Andaman and Nicobar Islands, India- 744 105, I. Jaisankar , Jerard B. Augustine ,   Project Coordinator, AICRP on Palms, ICAR- Central Plantation Crops Research Institute, Kasaragod, Kerala, Pari Prabhu ,   Division of Natural Resource Management, ICAR-Central Island Agricultural Research Institute, Port Blair, Andaman and Nicobar Islands, India- 744 105, T Subramani ,   Division of Natural Resource Management, ICAR-Central Island Agricultural Research Institute, Port Blair, Andaman and Nicobar Islands, India- 744 105, Moses Manasseh ,   Division of Natural Resource Management, ICAR-Central Island Agricultural Research Institute, Port Blair, Andaman and Nicobar Islands, India- 744 105, Asokan Hari Nivas ,   Field crop Improvement section, ICAR-Central Island Agricultural Research Institute, Port Blair, Andaman and Nicobar Islands, India- 744 105
Published: December 2024

In present study, the seed, seed oil, pulp and leaf of P. odorifer from three different geographical locations of Andaman and Nicobar Islands were analysed for its phytochemical and antioxidant properties which revealed that the pulp had excellent amount of carbohydrate (76.343 ± 1.531 %) as well as notable ascorbic acid (0.086 ± 0.112 %), added with good anti-nutritional contents like phenols (4.903 ± 0.967 %), flavonoids (17.223 ± 1.113 %), saponins (9.503 ± 1.194 %) and oxalate (0.593 ± 0.695 %) content. In addition, it also had good TSS (5.56 ± 1.064˚ Brix) content with exceptional antioxidant activity like DPPH (93.933 ± 3.95 % RSA) and ABTS (36.14 ± 0.118 % RSA). Notably, the seed had good protein (23.81 ± 2.757 %) content and the leaf had good tannin (10.98 ± 1.005 %), chlorophyll (5.278 ± 1.048 µg/g) and carotenoid (10.56 ± 1 µg/g) concentration added with notable hydroxyl radical scavenging activity (88.5 ± 4.951 %RSA). Exceptionally, the seed oil recorded good superoxide radical scavenging activity (89.14 ± 6.836 %RSA). Further correlation studies revealed strong correlation ascorbic acid with carbohydrates (r =1, p ≤ 0.05), DPPH (r =0.99, p ≤ 0.05) and carbohydrates itself with DPPH (r =0.97, p ≤ 0.05), saponins (r =0.90, p ≤ 0.05) and TSS (r =0.88, p ≤ 0.05). Good correlation levels of ABTS with tannins (r =0.94, p ≤ 0.05) and phenols (r =0.93, p ≤ 0.05) as well as flavonoids (r =0.81, p ≤ 0.05) were also observed. On analysis, these plant parts could have potent applications in the field of food, nutraceutical and pharmaceutical industries due to their exemplary antioxidant potential.
An Open-Labeled, Randomized Clinical Trial to Study the Performance and Safety of an Intravenous Line Organizer (IVO) in a Tertiary Care Hospital
Authors:   Director, Pharexcel Consulting Private Limited, Tata New Haven, Seshagirirao Palya Village, Dasanpura Hobli, Bengaluru North Taluka, Karnataka, India., Vikram Baburao , Venkatesh Renuka ,   Professor & HOD, Department of Community Medicine, Sapthagiri Institute of Medical Sciences and Research Centre, Navy Layout, Chikkabanavara, Bengaluru, Karnataka, India, Shetty Shruthi ,   Associate Professor, Department of Community Medicine, Sapthagiri Institute of Medical Sciences and Research Centre, Navy Layout, Chikkabanavara, , Karnataka, India, DS Priyanka ,   Assistant Professor, Department of Community Medicine, Sapthagiri Institute of Medical Sciences and Research Centre, Navy Layout, Chikkabanavara, Bengaluru, Karnataka, India, Kumar S Saveen ,   Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India, Burke Derryl ,   Independent Researcher, Mine Road, Bolton East, Quebec J0E IG0, Canada
Published: December 2024

Background: Medical line and tube entanglement poses a significant threat causing unintentional consequences to the patients.

Objectives: To study the clinical performance and safety of the IVO (intravenous line organizer) for providing patient autonomy, mobility, and comfort.

Methods: Patients aged <18 years (pediatrics) and >18 years (adults) who were admitted to the hospital for treatment were included in the study. Tools like the Global Scale, Ease of Operability Scale, Severity of Intravenous Line Entanglement by Medical Line Entanglement Scale, Subjective Presumption Questionnaire, and Skin Irritation Scale, and adverse and serious adverse events were assessed and analyzed.

Results: A total of 120 subjects who participated in the study were randomized into Groups-A (with IVO) and B (without IVO). The majority of patients in Group-A demonstrated better autonomy toward lines and tubes compared to Group-B in both adult and pediatric populations (86.3% vs 20%: Pediatric, 83.3% vs 26.6%: Adult), p<0.0001. Also, on mobility the Group-A patients reported improved movements with reduced restriction compared to Group-B (76.3% vs 26.6%, p<0.0001). Further, on the design and usability of IVO, 73.3% of patients in Group-A showed greater interest in the operability and usability compared to 27% in Group-B. No entanglement was reported in Group-A compared to the 12 (10%) patients facing potential harm of levels 2 & 3 who were in the standard-of-care group (without IVO). No significant adverse events were reported in patients using IVO.

Conclusion: The IVO provided patients with the safe organization of intravenous tubes with greater autonomy, mobility, and comfort in managing the IV lines.

Keywords: Intravenous Line Organizer, Autonomy, Mobility, Comfort, Entanglement
Effects of Girdling Treatments at Different Periods and Thicknesses on Grape Quality in Yalova Çekirdeksizi (V. vinifera L.) Grape Variety
Authors: Şahin Esra , Dardeniz Alper
Published: December 2024

This research was carried out in 2022 and 2023 to determine the effects of different thickness and single–double girdling treatments on grape quality in different phenological periods of Yalova Seedless grape variety grown in the 'Table Grape Varieties Application and Research Vineyard' located in the ‘ÇOMÜ Dardanos Campus, Faculty of Agriculture, Plant Production Research and Application Unit’. Within the scope of the research, a total of 9 treatments, including the control, were carried out in two different phenological periods pre–bloom and post–berry set, followed by two different thicknesses of single repeated girdling treatments, and double repeated girdling treatments during the veraison period. As a result; the decrease in yield in the 5 mm girdling treatments may be due to the removal of a thicker bark+phloem layer, resulting in a later closure of the wound tissues compared to the 3 mm girdling treatments, and thus a decrease in assimilate products to the main root and old parts. Therefore, it was concluded that although 5 mm girdling treatments continue to give positive results in terms of grape quality in many parameters, it is not appropriate to repeat them two years in a row in terms of average yield.
Trend Analysis of the Flow and Water Quality Data for the Broad River Basin, South Carolina, USA
Authors: Mete Betül , Nacar Sinan , Bayram Adem
Published: December 2024

Water quality is vital for human health and the protection of natural ecosystems. The demand for quality water is increasing day by day. It is known that changes in precipitation and temperature regimes due to climate change directly or indirectly affect water quantity and quality. In order to understand the potential effects of climate change on water resources, it is very important to know the changes in flow and water quality data over time. In this study, monthly, seasonal, and annual changes of dissolved oxygen (DO), water temperature (WT), discharge (Q), and specific conductance (SC) parameters, which are measured and recorded daily between 1987 and 2022 at four monitoring stations (two in the main branch and two in the tributaries) in the Broad River Basin (South Carolina, USA), were investigated using Mann-Kendall test and innovative trend analysis. Electrical conductivity (EC) values, calculated by considering SC and WT values, were considered. Mann-Kendall test and innovative trend analysis identified significant trends in 32.4 and 64.6% of the 272 time series analyzed, respectively. It was determined that innovative trend analysis was more sensitive in identifying decreasing trends. While the spatially and temporally varying trends in the river DO concentration and EC values were associated with human activities, it was concluded that the increasing trends in WT values and decreasing trends in Q values may be due to climate change on precipitation and air temperature parameters.
The Effects of Compost and Fertilization Applications on Plant Growth, Development and Nutrient Content in Leaves in Cut Tulip Cultivation
Authors: Alkaç Onur Sefa , Güneş Mehmet
Published: December 2024

In this study, grape pomace from a food processing factory was composted to create a new organic growing medium. The resulting compost was tested in cut tulip cultivation with 20% and 40% additions to the growing medium. In addition to the use of compost, chemical fertilization at different electrical conductivity (EC) levels (EC 0.75 dS m-1, EC 1.10 dS m-1, and EC 1.45 dS m-1) was applied. Phenology, pomology, and foliar nutrient contents were analyzed to determine the effects on tulip growth and flowering quality. Considering the results obtained, the highest flower stalk length (33.94 cm) and the longest perianth (42.71 mm) were found in the medium containing 20% compost. The longest vase life (8.94 days) was recorded in the medium containing 40% compost and EC level of 1.45 dS m-1. The highest branch weight (28.29 g) was measured in the medium containing 20% compost and EC level of 1.45 dS m-1. In the tulip variety ‘Jan van Nes’, 20% compost showed more favourable results than the control and 40% compost. Regarding fertilization, increasing EC levels limited plant growth. Nutrient contents in leaves increased macro and micro element contents with increasing EC levels and compost rates. In this study, it is suggested that the use of 20% compost can be used as an alternative organic material in growing media.
Foreign Capital Dynamics and Macroeconomic Performance in South Asia
Authors: Mouneer Salma , Yaqoob Iqra
Published: December 2024

Foreign capital is regarded as a vital resource for raising a developing nation's standard of living and wellbeing. Researchers and academics are concentrating on analyzing how foreign capital affects emerging nations. This study examines how foreign capital affects the economic growth of six South Asian nations between 2001 and 2020. The primary measures of foreign capital utilized in this study are official development assistance, foreign direct investment, and migrant remittances. The GDP growth rate is a measure of macroeconomic performance. The empirical analysis is conducted using sophisticated panel data estimate methods, Fully Modified Ordinary Least Square (FMOLS), and Dynamic Ordinary Least Square (DOLS). The study concludes that official development assistance has a negative impact on economic growth, whereas remittances and foreign direct investment have a beneficial effect.
Bacterial Morphology and Microscopic Advancements: Navigating from Basics to Breakthroughs
Authors: Sheikh Jahanzeb , Tian Swee Tan , Malik Sameen , Saidin Syafiqah , Suan Chua Lee
Published: December 2024

Bacterial morphology is critical in determining how these ubiquitous organisms function and behave. This study delved into the intriguing world of bacterial morphologies, offering thorough research regarding microorganisms' variable shapes and structures. It sheds light on the distinct traits and functions associated with their morphologies. Initially, the study highlighted the most common bacterial morphologies, ranging from the traditional rod and cocci to more complex patterns, including spirals, helices, and flat-wave structures. Each morphology revealed the structural traits that separate one from another. Moreover, a particular focus was placed on emerging advancements in the field, from conventional to recent advances in microscopic technologies that provided unique insights into microbial architecture. Furthermore, the review emphasized the importance of bacterial surface appendages, including flagella and pili, influencing microbial behavior and interactions. For instance, the corkscrew-like motion of helical bacteria is investigated in motility, emphasizing its importance in the survival and adaptability of specific species. Furthermore, in the realm of microscopic technologies, various options exist. However, recent literature revealed that scanning electron microscopy (SEM), field-emission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM) stand out as the most advanced microscopic techniques. Specifically, advancements such as super-resolution microscopy techniques, including structured illumination microscopy (SIM) and stochastic optical reconstruction microscopy (STORM), have revolutionized our understanding of pathogenesis and drug delivery. In conclusion, this review strengthens our understanding of bacterial morphologies while emphasizing the importance of taking a more diverse approach to investigating microbial structures. The combination of traditional knowledge and cutting-edge microscopy opens up new possibilities for discovery, promising a better understanding of bacterial shape and its consequences in scientific and medical fields.
Pharmacogenomics of Prostate Cancer: A Review of Recent Progress in Diagnosis, Personalized Medicine and Future Challenges
Authors: Bashir Fawad , Farooq Kinza , Irfan Ayesha
Published: December 2024

Prostate adenocarcinoma, in men, is the fifth leading cause of cancer casualties. Prostate cancer (PCa) is slow-growing with relatively low-grade aggressiveness. The prostate gland in the male reproductive system synthesizes and stores semen and seminal fluid. It sits inferior to the bladder, surrounds the superior part of the urethra and anterior to the rectum, and weighs approximately 20g in adult men. The prostate contains numerous small glands that produce 20% of the seminal fluid. In PCa, the cells of these glands undergo a malignant transformation and become cancerous. Single nucleotide polymorphisms (SNPs) are the most common type of gene variation, and many SNPs are associated with PCa risk. SNPs are small mutations in DNA sequences that can alter the structure and function of proteins. They are often inherited from parents and can vary frequently among different populations. SNPs in candidate genes, such as those involved in cell growth and differentiation, have been proven to increase susceptibility to prostate adenocarcinoma. Identifying SNPs linked with PCa risk can potentially upgrade early detection and disease prevention. The research on SNPs in PCa is still in its early stages. However, the findings to date suggest that SNPs have the potential to be valuable tools for the advancement of the diagnosis, prevention, and treatment of this devastating disease. For instance, rs6983267 and rs1447295 at the 8q24 gene in Caucasians and Asians have a strong association with prostate adenocarcinoma. In contrast, rs16901979 in the same gene in African Americans has shown a significant association with prostate malignancy. Meanwhile, in the European population, rs138213197 has a notable association with PCa. In addition to the association with the disease, SNPs may also be involved in treatment failure or toxicities in patients battling prostate carcinoma. For example, in the English population, rs4646487 CYP4B1 and rs2227291 ATP7A are responsible for toxicities in the treatment of prostate gland carcinoma. In this review, we summarize our understanding of how common genetic variations, SNPs, contribute to the development of PCa and how they may be used to screen for and manage the disease. SNPs are linked with a greater risk of aggressive PCa and represent essential biomarkers. However, in addition to confirming the association of these SNPs in larger cohorts, there remains a need to identify additional clinically relevant genetic biomarkers for screening, detection, validation of diagnosis, prevention, and treatment of prostate cancer.
Genetic Variation in CYP2D6 and Adverse Effects in Cardiovascular Patients on Metoprolol Therapy
Authors: Rafique Mehwish , Nasir Ayesha , Saleem Nida
Published: December 2024

The CYP2D6 genetic variation seems to be important for several clinically used drugs including metoprolol. The frequency of adverse effects of metoprolol may vary depending upon the genotype of CYP2D6.  However, how CYP2D6 genetic variation affects metoprolol's adverse effects is not well understood in the Pakistani population. In this study, we prospectively included Pakistani patients who started metoprolol treatment for cardiovascular indications. Decisions on inclusion and exclusion were made without awareness of the CYP2D6 genotype. Before intake of the first metoprolol dose, detailed medical history, baseline clinical characteristics, and laboratory indices were obtained. For CYP2D6 polymorphism examination, 5 ml of venous blood was collected and stored in a −80°C refrigerator until analysis. This study was approved by the Ethics Board of the Kohat University of Science & Technology and was conducted in line with the ethical guidelines of the 1975 Declaration of Helsinki. Our results showed that all the patients were wild type for this CYP2D6*6 (rs5030655) and no variant allele was found. For CYP2D6*4(rs1065852), 60 patients were wild type, 27 were heterozygous and only 3 patients were homozygous mutants for this single nucleotide polymorphism. Dizziness, bradycardia, and hypotension were more frequently observed adverse effects than lightheadedness and syncope. The frequency of adverse effects was hypotension (20), bradycardia (21), lightheadedness (16), dizziness (45), and syncope (13). The distribution of adverse effects in different genotypes of CYP2D6*4(rs1065852) reveals that this genetic variation is not associated with the adverse effects experienced by metoprolol users in a Pakistani cohort with cardiovascular indications.
La referencialidad clásica en la bipoética y transpoética costarricenses
Authors: Campos López Ronald
Published: December 2024

En este artículo se analiza hermenéuticamente la referencialidad clásica como recurso de bitextualización y transtextualización en una muestra de seis poemas costarricenses: “Hierba”, de Ioan Vidal (1960); “Dialéctica elemental” y “Razón de vida”, de Alfonso Chase (1978); “Sueño con Circe”, de Julieta Dobles (1992); “Preámbulo ante las puertas del laberinto”, de Johnny Mora Delgado (1993); “Ítaca”, de Randall Roque (2016); e “inercia 3–fiesta”, de Víctor Alba de la Vega (2022). Dichos textos se analizan desde la propuesta de los tres paradigmas de la poesía queer, y a partir de la identificación de siete figuras clásicas: Dioniso, Apolo, Circe, Calipso, Odiseo, Zeus y las ninfas. En estos casos, la referencialidad clásica funciona como recurso ya sea para pseudorrealizar o conseguir fantasiosamente el deseo transerótico; o bien, para expresar, política y estéticamente, el deseo y el ser libres de los sujetos bisexuales.
Revisión de mitos en la escritura feminista no mimética del siglo XXI
Authors: Vigna Gaetano Antonio
Published: December 2024

A lo largo de estas páginas, y teniendo como base cinco relatos hallados en la narrativa no mimética del siglo XXI, veremos cómo sus autoras (Patricia Esteban Erlés, Mónica Crespo, Ana Cristina Rossi, Tanya Tynjälä, María Fernanda Ampuero) se sirven del contenido mitológico y lo subvierten para visibilizar y cuestionar las prácticas de sexualización promovidas por la dominación masculina. Este empleo revisionista del género, que hace de la alteración de la materia mitológica una herramienta de revancha femenina y feminista, resemantiza los elementos de la tradición y arroja luz sobre las fuerzas que operan sobre el cuerpo de las mujeres.
Reseña: "Mujer, historia y mito en la dramaturgia femenina del México contemporáneo" (2023), de Carmen Alemany (ed.)
Authors: Martínez Campuzano Paola
Published: December 2024

Reseña: "Mujer, historia y mito en la dramaturgia femenina del México contemporáneo" (2023), de Carmen Alemany (ed.)
(D)escribir el Mundo: Construcción y Reconstrucción del Mito. Introducción al dosier
Authors: Ballester Pardo Ignacio , Munizza Elisa , Riesgo Ferran
Published: December 2024

Introducción al dossier