bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of heterovalently substituted slab perovskites Sr 2–xLnxBIV1–xBxIIIO4(BIV = Sn, Ti, BIII = Sc, In)
Authors: Titov Y.A. , Slobodyanik M.S. , Chumak V.V. , Tymoshenko M.V.
Published: March 2021

The possibility of the heterovalent substitution of A- and B-positions atoms in a single-layer slab perovskitelike structure of strontium titanate and stannate Sr2BIVO4 (BIV = Ti, Sn) by type Sr2–xLnxBIV1–xBxIIIO4 (Ln = La – Tb, BIV = Ti, Sn, BIII = Sc, In) has been established by X-ray powder diffraction methods. The boundaries of the heterovalent substitution of A- and B-positions atoms and the crystallographic parameters of the synthesized Sr2–xLnxBIV1–xBxIIIO4 phases with a single-layer structure are determined. The continuous phase area formation with a single-layer structure has been observed in 10 systems: Sr2–xLnxTi1–xScxO4 (Ln = La, Pr, Nd, Sm, Eu), Sr2–xLnxTi1–xInxO4 (Ln = La, Pr), Sr2–xLaxSn1–xScxO4, Sr2–xLnxSn1–xInxO4 (Ln = La, Pr). Increasing the degree of heterovalent substitution of atoms in these systems leads to a reduction of the sym metry of the crystal lattice of phases from the tetragonal (space group I4/mmm) to the interconnected rhombic one. In the rest of the studied Sr2–xLnxBIV1–xBxIIIO4 systems, the existence of a narrow (x value significantly less than 1) phase region with a single-layer structure based on Sr3BIVO7 is observed. The character of the phase relations in the Sr2–xLnxBIV1–xBxIIIO4 systems (Ln = La – Tb, BIII = Sc, In) (BIV = Sn, Ti) and the linear type of concentration dependences of the parameters of the reduced tetragonal unit cells of Sr2–xLnxBIV1–xBxIIIO4 phases with a single-layer structure indicate that, by their nature, these phases are series of solid solutions in the pseudobinary systems Sr2BIVO4 – SrLnBIIIO4 (BIV = Ti, Sn, BIII = Sc, In). The obtained data can be used to regulate the functional properties of titanates and stannates Sr2BIVO4 and materials based on them, as well as to solve the problem of a purposeful search for new compounds of the type An+1BnO3n+1 with a slab perovskite-like structure.
Koshland’s model as a method for the analysis of enzymatic deracemization reactions
Authors: Verovka О.S. , Kolodiazhna А.О.
Published: March 2021

Koshland’s four-point location model is applied to consider some enzymatic reactions of deracemization. The sequential model is a theory describing the cooperativity of protein subunits. It postulates that the conformation of the protein changes with each binding of a ligand, thus sequentially changing its affinity to ligands at adjacent binding sites. When the substrate binds to the active site of one subunit of the enzyme, the remaining subunits are activated. The possibility of the alternative binding of both substrates and products of the enzymatic reaction can be assessed on the basis of the known data on the structure of all four substituents at the chiral atom and their correspondence to the ligand specificity of the corresponding subsets of the enzyme. The made theoretical conclusions were tested by the example of the enzymatic deracemization of some hydroxyphosphonic acids. The replacement of ethoxyl groups at the phosphorus atom by isopropoxy groups and an increase in the volume of the substituent led to a significant increase in the enantiomeric excess of the hydrolysis product of hydroxyphosphonate. Hence, the conclusion is drawn that the key criterion for the efficient or inefficient passage of the reaction is the ratio of the sizes and the degree of hydrophobicity of the corresponding substituents at the asymmetric reaction center.
Lambl’s filaments as a cause for cardiogenic embolism of cerebral vessels and coronary arteries
Authors: Bogdan T.V. , Lizogub V.G. , Savchenko O.V. , Bogdan V.V. , Vinokurova А.S. , Orzheskovsky V.V.
Published: March 2021

The article presents a specific clinical case and literature data on a rare finding in the heart cavity — Lambl’s fila ments. Histologically, these are cells of fibroelastic tissue covered with stroma and epithelial layer. They do not have a vascular sheath, so they are devoid of granulation tissue. Lambl’s growths occur on both their own and prosthetic heart valves. Very rarely, threads can also be seen in areas other than heart valves such as the papillae, atria, and chords. These lesions can be seen on the echocardiogram accidentally or in connection with serious complications such as embolic stroke or acute coronary syndrome after their separation and distribution to distant organs. Lambl’s growths occur in adults and children, but the prevalence is higher in the former and increases with age. On the echocardiogram, the incidence reaches a peak between the ages of 61 and 70, and then decreases due to the aging of heart valves, which are increasingly calcified. The disease is more common in men than in women.
OLD INDUSTRIAL REGIONS OF UKRAINE: PROBLEMS AND TRENDS OF CONTEMPORARY DEVELOPMENT (ON THE CASES OF DONETSK AND LUHANSK OBLASTS)
Authors:   Nizhyn Mykola Gogol State University, Nizhyn, Baranovskyi M.O. , Smal V.V. ,   The United Nations Development Programme (UNDP) in Ukraine, Kyiv, Baranovska O.V. ,   Nizhyn Mykola Gogol State University, Nizhyn
Published: March 2021

Old industrial regions are the areas of concentration of numerous problems. Donetsk and Luhansk oblasts with their economic profile formed at the turn of the XIX-XX centuries belong to such type of territories. The main purpose of this study is the analysis of the development features, the search for the mechanisms to revitalise the regions of eastern Ukraine, especially after the beginning of the armed conflict in 2014. The development problems of the old industrial regions of Donbas are addressed in the article on the basis of in-depth statistical analysis and modern conceptual approaches to the reform of such territories. The study found that by the beginning of the armed conflict, the development path of Donetsk and Luhansk oblasts were typical of the old industrial regions. Due to the uneven extent of occupation of the economic potential, the regions of eastern Ukraine reacted differently to the events of 2014. Based on the analysis of the dynamics of macroeconomic indicators, the structure of the economy and investments, the article proves that currently Donetsk oblast has almost retained the main trends of previous development. However, the part of Luhansk oblast controlled by the government of Ukraine is gradually turning into an agro-industrial region and losing the features of the old industrial region. The recovery of the old industrial regions of Donbas should be based on real reindustrialization and post-industrialization, should include measures aimed at human capital development (change of mentality, overcoming paternalistic approaches, intensification of entrepreneurial activity) and the formation of a favourable business climate. The main tasks for Luhansk oblast now are overcoming regional disparities, logistical alienation of the northern districts and integration of the territory on new economic ties. The scientific novelty of the research lies in defining the features of the transformation of Donetsk and Luhansk oblasts economic landscape since the beginning of the armed conflict, substantiating the most relevant approaches to reforming the old industrial regions of Donbas.
FORMATION OF LAND USE RESTRICTIONS BY GEOINFORMATION ANALYSIS METHODS IN SPATIAL PLANNING (ON THE EXAMPLE OF TERRITORY AROUND THE AIRFIELDS)
Authors:   National Academy of Agrarian Sciences of Ukraine, Kyiv, Novakovskyi Leonid , Martyn Andrii ,   National University of Life and Environmental Sciences, Kyiv, Novakovska Iryna ,   National Aviation University, Kyiv, Slavin Igor ,   National Aviation University, Kyiv, Skrypnyk Liliia ,   National Aviation University, Kyiv
Published: March 2021

The purpose of the publication is revealing the features of the geospatial analysis implementation and special software for effective territorial development on the example of the interaction of aviation land use with adjacent territories and global urbanization centers. The necessity of using remote sensing data together with GIS technologies for creation of models and visualization of future synergetic connections of airport infrastructure development and urban land use have been substantiated. Ways of improvement the implementation of planning decision-making processes and regional development under the condition of using high-tech remote sensing-GIS methods as a basis for increasing the level of economically efficient, environmentally balanced, socially orderly land use have been proposed. Changes and additions are offered according to normative-legal acts of regulation of the land use system of aviation transport.
The Determinants of Economic Growth: Empirical Study of 10 Asia-Pacific Countries
Authors: Nasir Muhammad Safar , Wibowo Ana Rahmawati , Yansyah Dedy
Published: March 2021

The purpose of this research to examine influence several independent variables, especially corruption, foreign direct investment (FDI), population growth, and government expenditure on the economic growth of 10 Asia-Pacific countries, and prove the hypothesis of the sand wheels theory whether corruption causes a decline and a slowdown in economic growth. This study uses panel data. The results showed that the variables of corruption have a negative impact on economic growth, foreign direct investment (FDI), and government expenditure have positives that significantly affect the level of economic growth in 10 Asia-Pacific countries. However, population growth does not significantly affect economic growth. The result implies that corruption has a negative effect on economic growth in 10 Asia-Pacific countries. Such an outcome provides evidence and confirms the hypothesis that corruption can sand the wheel of an economy. Countries must eradicate all forms of corruption and maintain a conducive investment climate so that there is a level of trust, especially in the Asia-Pacific countries, to create productive economic growth.JEL Classification: O47, D73, C12How to Cite:Nasir, M. S., Wibowo, A. R., & Yansyah, D. (2021). The Determinants of Economic Growth: Empirical Study Of 10 Asia-Pacific Countries. Signifikan: Jurnal Ilmu Ekonomi, 10(1), 149-160. https://doi.org/10.18752/sjie.v10i1.15310.
Policy Model for Muslim State Inflation Control
Authors: Firmansyah Hamdan
Published: March 2021

Inflation is a problem which is not simple and is classified as an economic disease. Inflation is one important indicator in analyzing a country's economy, especially with regard to its broad impact on macroeconomic variables: economic growth, external balance, competitiveness, and even income distribution. Inflation is characterized by high and continuous increases in prices not only causing some adverse effects on economic activity, but also on the prosperity of individuals and society. An increase in the price of one or two items alone cannot be called inflation, unless the increase extends to an increase in the majority of other goods.
An application of the SERVQUAL model to study the quality perceived by customers in a pizzeria
Authors: Dos Santos Lucas Oliveira , Muniz Emerson Cleister Lima , Pereira Emily Nadine , Dandolini Gertrudes Aparecida , De Souza João Artur
Published: March 2021

Purpose - To propose a set of measures to improve the services provided by a company in the food sector by adapting and applying the SERVQUAL model.Design/methodology/approach – This study uses a survey to collect data and information about the object being analyzed by giving questionnaires to the company's customers. For this, the population was defined along with the ideal sample to be achieved using the Simple Random Sampling method, considering a 5% sampling error and 95% reliability.Findings - The findings indicate a negative general evaluation in all five dimensions of quality analyzed, highlighting that only 17.4% of the 23 items analyzed in the study had positive results in the relational analysis between expectation and perception compared to the 82.6% that do not present this.Originality/Value - The in-depth analysis carried out in this study gave entrepreneurs a more detailed view of the actual state of the establishment, indicating the points that need to be improved urgently and that have directly affected the negative evaluation obtained by the establishment. The need to set up a better marketing plan, a change to the location of the establishment, and the urgent improvement of safety, were highlighted as items identified that need immediate change.Keywords: Food services. Quality in services. SERVQUAL. Satisfaction analysis. Pizzerias.
Estudo dos processos de fabricação de estruturas metálicas para linha de transmissão
Authors: Sabino Hélia Rejane Torres , Loos Mauricio Johnny
Published: March 2021

Objetivo - Descrever os processos de uma linha de produção na fabricação de estruturas metálicas para linha de transmissão.Desenho / metodologia / abordagem - O trabalho adota o estudo de caso como abordagem metodológica. Para a coleta dos dados foram utilizadas fontes diretas, o conhecimento do pesquisador e a experiência adquirida no dia a dia do trabalho na empresa, bem como a coleta de dados juntamente com o fornecedor.Resultados - Os resultados mostram que todos os processos envolvidos nas atividades da linha de produção são acompanhados pelo Sistema de Gestão da Qualidade, o qual analisa os projetos para que à produção de todos os componentes das estruturas metálicas estejam de acordo com as especificações e normas técnicas.Originalidade / valor - O estudo descritivo não só analisa os processos de produção em massa em estruturas metálicas, como também aplica padrões exigidos conforme Normas.Palavras-chave - Processos. Fabricação. Produção. Qualidade. Projetos.
Systematic literature review of Brazilian research on multivariate control charts
Authors: Ueda Renan Mitsuo , Da Rosa Leandro Cantorski , Da Silva Wesley Vieira , Agostino Ícaro Romolo Sousa , Souza Adriano Mendonça
Published: March 2021

Purpose – This paper aims to present a Systematic Literature Review (SLR) of studies in Brazil with applications of multivariate control charts indexed in journals on the Web of Science.Design/methodology/approach – The following steps were carried out: a detailed synthesis was performed on the general characteristics of the corpus, co-citation and collaboration networks analyzed; and a co-occurrence of terms in the text corpus was verified. A Systematic Literature Review was carried out using the protocols set out by Biolchini et al. (2007), Kitchenham (2004) and Tranfield, Denyer and Smart (2003). Papers were selected from the Web of Science database, and after applying filters, results for 29 articles were given to compose the corpus.Findings – A tendency was found for an increase in publications, along with more international research on the issue. The journal most used for publication was the Microchemical Journal. This analysis provided relevant authors for research in this area: Harold Hotelling, Douglas Montgomery, and John Frederick MacGregor. Important Brazilian researchers were highlighted who work mainly in the pharmaceutical and biodiesel industry.Originality/value – No articles were found that had carried out a Systematic Literature Review of Brazilian research on multivariate control charts. The main contributions to this manuscript related to an increase in scientific know-how in the area of multivariate and bibliometric analysis.Keywords - Multivariate Control Charts. Systematic literature review. Bibliometric analysis.
Organization Culture and Quality Management System: A Systematic Literature Review
Authors: Sanches Rafael Augusto de Oliveira , Ferreira Eric de Paula , Parreiras Fernando Silva
Published: March 2021

Purpose – Aiming to fulfill the need to consolidate and carry out a critical analysis of the studies developed on Organizational Culture and Quality Management Systems, this study aims to understand the relationship between these concepts through a systematic review of the literature.Design/methodology/approach – This study is descriptive and is predominantly classified as a quantitative approach. Using the systematic literature review technique, publications contained in the Materials Science & Engineering Database, Emerald Insight, OneFile (GALE), Taylor & Francis Online - Journals, ScienceDirect Journals (Elsevier), Elsevier (CrossRef), Directory of databases were analyzed Open Access Journals (DOAJ), MEDLINE / PubMed (NLM), Library & Information Science Collection and Springer (CrossRef) and 22 studies that deal with the topics in an integrated manner were used.Findings – The analysis shows that the Cameron and Quinn (2011) and Hofstede (2003) models are the most used. Regarding the business sectors in which studies were carried out, no research relating to the topics studied in utilities companies had been carried out, with most of the studies (38%) carried out in companies in the industrial sector.Originality/value – With regard to aspects of quality management relating to organizational culture, there is a balance between the hard and soft elements in the literature and that most studies put forward the management levels of companies as the target audience for the data source.Keywords - Organizational Culture, Management System, Quality Management System, Systematic Literature Review.
Analysis of waste collection using different modes of transport: Planning scenarios through system dynamics
Authors: Rodrigues Glauco Oliveira , Santos Wellington Furtado , Simonetto Eugênio De Oliveira , Zazyki Marco Aurélio Denis , Silva Ricardo Cesar , Dalmolin Luiz Cláudio , Modro Nilson Ribeiro
Published: March 2021

Purpose – This paper aims to compare rail and road modes of transport to carry Municipal Solid Waste using a simulation based on the Systems Dynamics of the financial and environmental differences between both.Design/methodology/approach – For modeling, the methodology proposed by Law (2015) based on Systems Dynamics was adopted. As such, the Systems Dynamics methodology helped to map structures for the system developed, seeking to examine its interrelation in a broad context. Through this simulation, the applied dynamics sought to understand how the system in question evolved over time and how changes in its parts affect its behavior. From this understanding, the system could be diagnosed and predicted, in addition to allowing more scenarios to be simulated over time. The time horizon used was eleven years.Findings – The findings show that, as seen from a financial perspective, there is a large difference between road and rail modes of transport to carry MSW. Therefore, it demonstrates the importance of valuing the railroads, in addition to being another option for managers to collect and transport waste generated in the municipalities studied.Originality/value – The model developed can be used by managers in the area of Municipal Solid Waste as a focus to help in the decision-making process to choose logistical options to transport waste.Keywords – Municipal Solid Waste; Modes of Transport; Systems Dynamics; Rail, Road.
A THEORETICAL STUDY OF OSCILLATIONS OF TWO IMMISCIBLE FLUIDS IN A LIMITED TANK
Authors:   Bauman Moscow State Technical University (Moscow, Russian Federation), Win Ko Ko , Temnov A.N. ,   Bauman Moscow State Technical University (Moscow, Russian Federation)
Published: March 2021

In the paper, the nonlinear oscillations of a two-layer fluid that completely fills a limited tank are theoretically studied. To determine any smooth function on the deflected interface, the Taylor series expansions are considered using the values of the function and its normal derivatives on the undisturbed interface of the fluids. Using two fundamental asymmetric harmonics, which are generated in two mutually perpendicular planes, the differential equations of nonlinear oscillations of the two-layer fluid interface are investigated. As a result, the frequency-response characteristics are presented and the instability regions of the forced oscillations of the two-layer fluid in the cylindrical tank are plotted, as well as the parametric resonance regions for different densities of the upper and lower fluids. The Bubnov-Galerkin method is used to plot instability regions for the approximate solution to nonlinear differential equations. At the final stage of the work, the nonlinear effects resulting from the interaction of fluids with a rigid tank that executes harmonic oscillations at the interface of the fluids are theoretically studied.
The impact of Ki-67 index, squamous differentiation and several clinicopathologic parameters on the recurrence of low and intermediate-risk endometrial cancer
Authors: Ocak Birol , Atalay Fatma Öz , Sahin Ahmet Bilgehan , Ozsen Mine , Dakiki Bahar , Türe Seray , Mesohorli Merve , Odman Hikmet Utku , Tanrıverdi Özgür , Ocakoğlu Gökhan , Bayrak Mehmet , Ozan Hakan , Demiröz Candan , Sali Seda , Orhan Sibel Oyucu , Deligönül Adem , Cubukcu Erdem , Evrensel Türkkan
Published: March 2021

Endometrial endometrioid carcinoma (EEC) represents approximately 75–80% of endometrial carcinoma cases. Three hundred thirty-six patients with EEC followed-up in the authors’ medical center between and 2010–2018 were included in our study. Two hundred seventy-two low- and intermediate- EEC patients were identified using the European Society for Medical Oncology criteria and confirmed by histopathological examination. Recurrence was reported in 17 of these patients. The study group consisted of patients with relapse. A control group of 51 patients was formed at a ratio of 3:1 according to age, stage, and grade, similar to that in the study group. Of the 17 patients with recurrent disease, 13 patients (76.5%) were stage 1A, and 4 patients (23.5%) were stage 1B. No significant difference was found in age, stage, and grade between the case and control groups (p>0.05). Body mass index, parity, tumor size, lower uterine segment involvement, SqD, and Ki-67 index with p<0.25 in the univariate logistic regression analysis were included in the multivariate analysis. Ki-67 was statistically significant in multivariate analysis (p=0.018); however, there was no statistical significance in SqD and other parameters. Our data suggest that the Ki-67 index rather than SqD needs to be assessed for recurrence in patients with low- and intermediate-risk EEC.
Effects of learning style based differentiated activities on gifted students’ creativity
Authors: DEMİR Serkan
Published: March 2021

This study aims to investigate how effective are differentiation and enrichment of an instructional design in revealing and improving creative thinking skills of gifted and talented learners. Pre-test and post-test experiment-control group quasi-experimental design was used in this study. The subjects of the study consisted of 72 students aged 10 to 11 years, who were identified as gifted and talented and who are currently attending the same Science and Arts Center (BİLSEM) in the province of Istanbul. When the findings were interpreted, it is possible to conclude that the instructional design that was differentiated and enriched by means of the Kolb’s learning styles the Bloom’s taxonomy had positive effects on revealing and improving creative thinking skills of gifted and talented learners. Based on the findings obtained within this study, we could recommend that teachers, who would like to support and develop their students’ creative thinking skills, should first start with identifying the potentials, interests and learning styles of their students; then provide them with a learning environment where the students can demonstrate their creativity, defend their ideas freely, and produce unique solutions to the problems that they face; and finally employ the approaches, methods, or techniques that improve creative thinking and whose effectiveness is scientifically proven in the literature.
Gifted and talented students in sports in the Slovenian primary school system
Authors: VOLMUT Tadeja , KUKANJA GABRIJELCIC Mojca , RAJOVEC Nıka
Published: March 2021

The aim of this study was to determine the attitudes of the educational staff and their assessment of their competence in the field of discovering and working with gifted and talented students in sports. Forty classroom teachers and 40 physical education teachers were included in the study. We used a questionnaire designed for the purposes of this study. The results show that teachers are aware of the role and importance of discovering and working with gifted and talented students, but that they need additional professional training to avoid possible mistakes and problems they might encounter in their work. The teachers believe that their school takes the serves the area of discovering gifted and talented students (X ̅= 3.50 (0.91); p ˂ 0.001), somewhat less the area of educational work with them (X ̅ = 3.39 (0,77); p <0.001) and for the systemic and operational regulation of the education of gifted and talented students (X ̅= 3.35 (0.94); p = 0.001). Physical education teachers identified more children who were gifted or talented in sports than class teachers (t(78) = -5,979, p< 0,000). The scientific contribution represents an important contribution in the field of work with talented and talented students, as for the first time in Slovenia the views of the pedagogical staff and their assessment of competence with such a group of students are presented. We conclude with a critical presentation of some gaps and an overview of the existing situation as well as with some guidelines for further pedagogical and scientific research.
Staphylococcal Protein-A and Chimeric Protein-LAG sandwich ELISA v1
Authors: A Justiz-Vaillant Angel
Published: March 2021

This ELISA was used to study the interactions between Staphylococcal protein-A (SpA) and protein-LAG (PLAG) with different immunoglobulin preparations from mammalian and avian species.
Chimeric Protein-LAG and Protein LA sandwich ELISA v1
Authors: A Justiz-Vaillant Angel
Published: March 2021

This ELISA was used to study the interactions between protein-LAG (PLAG) and protein-LA (SpLA) with different immunoglobulin preparations from mammalian and avian species.
The effect of prophylactic use of intravenous tranexamic acid in abdominal hysterectomy
Authors:   Associate Professor, Ananta Institute of Medical Sciences and Research Centre (A.I.M.S.R.C), Rajsamand, Rajasthan, India, Barya Dr. Smita , Goyal Dr. Sameer ,   Associate Professor, PDCC Cardiac Anaesthesiology, Pacific Medical College and Hospital (PMCH), UDAIPUR, Rajasthan, India
Published: March 2021

Introduction: Hysterectomy is one of the frequently performed major gynecological surgicalprocedures for various uterine pathologies. The objective of this study is to assess the effect ofintravenous tranexamic acid in reducing intraoperative and postoperative blood loss in womenundergoing abdominal hysterectomy. Materials and Methods: The study was a randomizeddouble-blind study, involving a total of 120 women undergoing abdominal hysterectomy for benignetiology were randomly assigned to two groups: Group 1 (non TA): (n=60) women receiving normalsaline and Group 2 (TA): (n=60) women receiving prophylactic Tranexamic Acid in 100 ml saline IVjust before skin incision. The primary outcome was intraoperative, postoperative, and all blood lossestimation. Results: Group 2 (TA) showed a great reduction in intraoperative and postoperativeblood loss (blood in the intra-abdominal drain) compared with Group 1 (non TA), (P = 0.0001,0.0001), so the overall estimated blood loss in groups 2 showed significant reduction compared withGroup 1 (P = 0.0001). Conclusion: Intravenous tranexamic acid is a safe and reliable method tohelp decrease blood loss during and after abdominal hysterectomy.
The role of biomarkers in the early diagnostics of breast cancer
Authors: Ismagilov A. Kh. , Khuzina D. R. , Vanesyan A. S. , Zaysteva V. V.
Published: March 2021

One of the main priorities in modern oncology is the identification and clinical application of biomarkers that can be helpful in the diagnostics and prognostication of cancer. The aim of this article was to review biomarkers for early diagnosis and prediction of prognosis of breast cancer. There were reviewed three main groups of biomarkers in this article: familial breast cancer biomarkers with high and low penetration (BRCA1, BRCA2, TP53, etc.), biomarkers of breast cancer molecular subtypes (luminal A and luminal B, HER2/neu, basal and low in claudine) and biomarkers of early stage breast cancer progression (multigenic panels).
MAIN DIRECTIONS OF REGULATING SPORTS ACTIVITIES IN THE UN
Authors: Zakharova L. I.
Published: March 2021

The article outlines main directions of international legal regulation of physical culture and sport in the United Nations system at the present stage. The author analyzes the powers of the UN General Assembly and its subsidiary body — the Human Rights Council, the UN Security Council, and the Department of Economic and Social Affairs of the UN Secretariat. The author demonstrates how an unfavourable outcome of a football match can become a catalyst for aggravating an interstate dispute and its subsequent transfer to the International Court of Justice. The article describes the interaction between the Olympic movement and two of the UN specialized agencies — the United Nations Educational, Scientific and Cultural Organization and the World Health Organization.
UNITED NATIONS ACTION IN THE FIELD OF TRADE FACILITATION
Authors: Sidorov V. N. , Sidorova E. V.
Published: March 2021

Trade is defined as one of the key enabler of implementation of the Sustainable Development Goals Agenda 2030. Trade facilitation is important trend of trade in sustainable development, as expected will promote of growth acceleration and international trade and also will enhance economic, ecological and social aspects of sustainable development. In article is offered to consider the main activities of the United Nations in the trade facilitation. In the article it is offered to consider the main activities of the UN in the sphere simplification of procedures of trade The article considers the work of the United Nations in the of trade facilitation field, in particular the work of the United Nations, sustainable development, trade facilitation, International law, United Nations Commission on International Trade law, United Nations Conference on Trade and Development, United Nations Industrial Development Organization, United Nations Economic Commission for Europe, United Nations Centre for Trade Facilitation and Electronic Business, United Nations Economic and Social Commission for Asia and the Pacific, United Nations Network of Experts for Paperless Trade in Asia and the Pacific.
Notas sobre la vivienda rural en Asturias entre los siglos XIX y XX a través de las topografías médicas
Authors: Rodríguez Pérez Santiago
Published: March 2021

Las topografías médicas son trabajos en los que se estudian las condiciones ambientales y materiales de un territorio, con el objetivo de realizar acciones preventivas para mejorar la sanidad y la higiene públicas. En ellas, además de cuestiones sanitarias, se analiza también la geografía, clima, fauna y flora, urbanismo, demografía, economía, historia, etc. Este género de literatura científica, que tuvo su apogeo a finales del siglo XIX y principios del XX, es una fuente de interés para la investigación histórica. En el caso asturiano además resulta excepcional, ya que se realizaron más de cincuenta trabajos que cubren buena parte del territorio de la comunidad. A partir de los datos que proporcionan sobre las condiciones de vida en el medio rural, ofrecemos una breve síntesis de la situación del hábitat doméstico, sus problemas y transformaciones en las primeras décadas del siglo XX.
Arraigados en la tierra
Authors: Fernández García Noelia
Published: March 2021

Reseña del libro Arraigados en la tierra. 30 muebles seleccionados de una colección privada, publicado en 2020 por Mónica Piera Miquel.
Dionisio Aguilar. "Aparejador de las obras del nuevo Palacio Real de Madrid en el ramo de maderas finas"
Authors: Sanchez Casado Antonio
Published: March 2021

El Real Taller de Puertaventanería ha sido uno de los grandes olvidados a pesar de la importancia que tuvo en la segunda mitad del siglo XVIII. Obras como la Biblioteca de Carlos IV, La Librería de la Real Botica o la de el Observatorio Astronómico de Madrid, justificarían su puesto entre los mejores trabajos de la ebanistería real. Dionisio Aguilar fue su director durante más de cincuenta años y la historia del mueble debe colocar su nombre en el lugar que le corresponde.
Los muebles de la familia Montal-Pascual, un conjunto de ebanistería de Francesc Mogas
Authors: De la Fuente Bermúdez Vicente
Published: March 2021

El descubrimiento de un conjunto de muebles, de los cuales una parte se pueden asignar con seguridad al taller de ebanistería de la familia Mogas, aporta nuevo datos respecto al tipo de clientela y el funcionamiento, de este tipo de talleres; pequeñas industrias de caracter familiar, con una producción de alta calidad destinada a las clases medias y burguesas de la ciudad y que, en la línea marcada por los grandes artífices, contribuyeron a difundir las nuevas modas y dotar a los interiores barceloneses del confort y modernidad exigido por los nuevos estilos de vida.
Management of pregnant women in times of COVID-19 our experience from Kashmir valley
Authors: Naseer Syed , Andrabi Syed Uzma , Andrabi Syed Ishfa , Tabasum Humaira
Published: March 2021

Background: The coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, is a global public health emergency. COVID-19 is a rapidly evolving situation, and there is limited data reporting its impact on pregnant women. Our study aimed to find the symptomatology, clinical courses and outcome of pregnant women with COVID-19 and to assess the vertical transmission potential of COVID-19 in pregnancy.Methods: This prospective observational study was conducted at Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Medical College, Department of Gynaecology and obstetrics, Srinagar from May 2020 to September 2020. All COVID-19 positive pregnant patients admitted in our institution were included in our study.Results: The study included 100 Covid-19 positive pregnant women. Most of them were between 30 to 40 years of age. Median gestational age was 32.8 weeks. Comorbidity was present in 18 of our patients. 7 patients had gestational diabetes and 1 with overt diabetes, 5 were hypertensive, 3 had hypothyroidism, 1 with anti-phospholipid antibody syndrome (APLA) and 1 with asthma.44 patients were primigravidae and 56 were multigravidae. 27 patients delivered preterm and 44 with term pregnancy. 47 had undergone caesarean section and 24 normal vaginal delivery.88% of our patients were asymptomatic for covid-19 disease while as 12 patients had Covid-19 disease symptoms. The main complaints reported by patients related to covid-19 disease was mild dry cough and fever (9%). Two patients developed severe covid-19 pneumonia with ARDS and were put on ventilator, expired after 20 days of illness. All neonates were subjected to RT-PCR with none producing positive results.Conclusions: Appropriate and timely management of Covid-19 positive pregnant women is a principle for safe motherhood and healthy offspring in times of global pandemic. The present data do not suggest an increased risk of severe disease among pregnant women. We encourage the breast feeding immediately after delivery as benefits overweigh any potential risks of virus transmission if any.
Awareness and knowledge of hearing loss, hearing management modalities, speech and language pathology among general public in Buraidah, Saudi Arabia
Authors: Alsaawi Omar Khalid , Alharbi Saif Mohammed , Althunian Abdulrahman Mohammed , Alahmad Mohammed Fahad
Published: March 2021

Background: Awareness toward ear health, hearing loss hearing management modalities, speech and language pathology is necessary for early treatment and management. Methods: This is a cross-sectional study that was conducted at two malls during October 2020 in Buraidah city, Qassim province. The questionnaire was designed to examine the demographics, education and awareness. Specific awareness questions about hearing loss, hearing management modalities, speech and language pathology were included to examine their knowledge about these pathologies. All statistical analyses were carried out using SPSS version 21. Results: The overall mean awareness score of hearing loss was 5.03±1.78 out of 13 points with poor and good level had been detected among 62.6 and 37.4% of respondents, respectively. For the awareness of ear and hearing management, the overall awareness score was 4.82±1.36 out of 7 points with 52.7 and 37.4% being classified into poor and good level, respectively. In the awareness toward speech development, the total awareness score was 2.64±0.98 out of 4 points with 41.8 and 58.2% were considered as poor and good awareness level, respectively. Statistical test revealed that individuals >25 years had significantly better awareness toward hearing loss (T=-4.331; p<0.001) and awareness toward speech development (T=-2.628; p=0.009).Conclusions: The awareness toward hearing loss, ear and hearing management seems to be lacking. More awareness campaigns, lectures, advertisement in social media about these pathologies and other educational methods are needed in order to fill the gaps in general awareness, more importantly in the awareness of hearing loss, ear and hearing management.
Luteal Phase Defect (LPD): A necessary tool in assisted reproductive techniques
Authors: Pant P R , Shrivastava Uma , Simkhada Sabina , Sharma Swasti , Shrestha Chetna , Shrestha Usha , Lacoul Tumla
Published: March 2021

In Luteal Phase Defect (LPD), endogenous progesterone is insufficient to maintain a functional secretory endometrium and also inhibit embryo growth and implant. In 1960, it was estimated that 20 million pregnancies were exposed to Dydrogesterone in utero. LOTUS I and LOTUS II two major multicenter Phase III studies were conducted on patients who were planning to undergo Fertilization (IVF) with or without Intracytoplasmic Sperm Injection (ICSI). The result of both studies shows that Dydrogesterone was non-inferior to micronized vaginal progesterone, which was the presence of fetal heartbeats at 12 weeks of gestation. Progesterone which can be administered either by oral preparation, vaginal administration along with optimal use of estrogen and Gonadotropin-Releasing Hormon (GnRH) agonist drugs is used in the treatment of LPD. Studies have suggested the use of Dydrogesterone in fresh IVF cycles and Luteal Phase Support (LPS) is continued till 10–12 weeks. However, it may be stopped at the time of β-hCG becoming positive or visualization of a fetal heartbeat.
Decline in blood loss with use of tranexamic acid in cases of hysterectomy: A retrospective observational study in a teaching hospital of central India
Authors: Shikha  , Jain Sapna Bajaj
Published: March 2021

: Hysterectomy the most commonly performed gynaecological surgery world over is mostly a planned surgery commonly done for benign uterine conditions, though relatively high rates of complications have been reported. Blood loss during surgery seems to be a major complication. Anaemia being prevalent in Indian women, adds to the risk of prolong recovery time and postoperative morbidity with excessive blood loss intra operatively. Tranexamic acid (TXA) being an anti fibrinolytic agent have been found to decrease blood loss and requirement of blood transfusion in various surgical procedures and aids in better recovery.

To find the effectiveness of tranexamic acid in decreasing blood loss in patients undergoing hysterectomy for benign indications and the need for blood transfusion.

Type of study- Retrospective observational study over a period of 1 year in 200 patients.

Study was conducted in Obstetrics and Gynaecology department of L.N. medical college, J.K hospital and research centre Bhopal.

Approval for conducting study from ethical committee of hospital was taken. A retrospective analysis of all patients record was done who underwent hysterectomy for benign indications over the study period of one year and patient were sorted out in two groups, one (group 1) who received tranexamic acid (TXA) during surgery and other one (group 2) who did not receive TXA during surgery.

Outcome of the study was assessed on following parameters - amount of blood lost (measurement of blood loss was done by the amount of blood collected in suction bottle and soiled mops), postoperative haemoglobin level after 24 hours of surgery, blood transfusion requirement, duration of hospital stay.

Significantly less intraoperative loss of blood and need for blood transfusion was found in group 1 as compared to group 2. (P=0.0001).

In the present study we concluded that a single dose of tranexamic acid given during surgery significantly reduces the blood loss, operating time and need for blood transfusion in patients undergoing hysterectomy for benign indications. Tranexamic acid being an anti fibrinolytic agent can be safely recommended as prophylactic measure for reducing blood loss in hysterectomies specially in low resource setting.
A retrospective analysis of spectrum of presentation of adenomyosis in tertiary centre
Authors: G S Anitha , K Rashmi , Radhika  , S Sukanya , C Savitha
Published: March 2021

Benign invasion of endometrial tissue into the myometrium of uterus is known as adenomyosis. It is found typically between the age of 35-50 years. Prevalence is 6- 39%. Modern imaging techniques, both ultrasound (TAS, TVS) and MRI have made possible, for the first time, a non-invasive identification of adenomyosis.

To analyse the spectrum of presentation of adenomyosis and to determine the accuracy of clinical examination and imaging modalities in the diagnosis.

It is a retrospective study done at hospitals attached to Bangalore Medical College & Research Institute during august 2016-august 2017. The HPE reports and case records of all the hysterectomy specimens were reviewed. Data regarding age, parity, symptoms, obstetric history, examination, co morbidities, investigation findings, associated pathology and treatment modality were noted. They were tabulated and analysed.

Out of the 50 patients, 56% were in the age group of 41-50 years. The prevalence of adenomyosis in our study was only 10% in post-menopausal women when compared to the age group 41-50yrs (56%). Multiparous women had 94% incidence of adenomyosis. 26% of women had prior uterine surgeries. 22% of cases had history of infertility in this study. 56% had menstrual disturbances. Dysmenorrhea & Dyspareunia were the next common symptoms. Fibroid was the commonest associated pathology (38%). 34% had hyperplasia of endometrium whereas 66% had no pathology. Imaging picked up only 40% of cases contrary to 36% of clinical diagnosis and was raised to 66% with gross examination of specimen and 100% with HPE.

Adenomyosis has a varied presentation. Ultrasound fails to diagnose all the cases. Clinical examination is a better modality. Associated pathology may mask the clinical features of adenomyosis, and diagnosis may be missed. Presently HPE is probably the gold standard for diagnosing adenomyosis.
A comparative study of efficacy of DIPSI and O’Sullivan’s method of screening for GDM in a high risk tertiary referral hospital
Authors: G S Anitha , K Rashmi , D Tejaswini , Radhika  , S Sukanya
Published: March 2021

There is an increasing trend of making Diabetes one of the most common non-communicable diseases globally. Gestational Diabetes Mellitus (GDM) is defined as “carbohydrate intolerance variable severity that is first diagnosed during present pregnancy, regardless of the need for insulin or persistence of the diabetic state after delivery”. Diabetes Mellitus is the most common disorder of pregnancy, although the prevalence is usually reported as 2 to 5% of pregnant women, it can be as high as 14% in high risk groups.

To note the Foetal Outcome of pregnancy with impaired and abnormal glucose tolerance detected with DIPSI.

Total of 200 patients was included in the study from Vanivilas hospital for 1 year. A detailed history from antenatal patients was taken to reveal all risk factors. The procedure of the study was explained and required consent for the study was taken. Examination of the patients was done and all relevant data was obtained. Fasting blood glucose was taken of all antenatal patients at their first visit. Pregnant women at 24-28 weeks were tested with 50g oral glucose load or 75g oral glucose load, at random. Patients were give 50g glucose irrespective of the meal and 1 hour venous blood sample was collected. Patients of 75 g of oral glucose were asked to come in fasting state, 75g of glucose was given, and following which 2 hour venous sample was collected. Blood glucose was tested by GOD-POD method. Diagnosis of GDM was made when the plasma glucose of >140mg/dL and impaired glucose tolerance diagnosis was made when plasma glucose was between 120-140mg/dl.

High prevalence rate of GDM was obtained in our study, GDM has adverse maternal and fetal outcome. GDM when identification early and treatment initiated for mothers, maternal and fetal complications can be reduced. In conclusion, intensive care of GDM mothers can help primary prevention of obesity, impaired glucose tolerance and diabetes in the offspring.
Lantern on Saint Paul’s dome - A case report of cervical fibroid
Authors: Geetha A Mangala
Published: March 2021

Leiomyoma are the commonest benign tumors affecting the female reproductive tract and constitute to around 18-20% of the uterine pathologies that are seen in women of the reproductive age group. Depending on its location in the uterus, fibroids are classified as uterine, cervical and ligamentary of which the cervical fibroids are the rarest and make up only around 2-2.5% of the total incidence of fibroids. Large cervical fibroids give a typical appearance known as “Lantern on St. Paul’s dome” where the small sized normal uterus sits on top of the cervical fibroid mimicking the Lantern on the dome of famous St. Paul’s Cathedral of Russia. This is a report of a case of cervical fibroid which showed the typical appearance and was successfully operated with no organ damage or blood loss.
Ectopia cordis with omphalocele and exencephaly – A case report
Authors: Derkar Surabhi
Published: March 2021

Ectopia cordis is an extremely rare congenital anomaly where the heart is in extrathoracic location partially or completely. We report a case of a 25-year-old primigravida with uneventful pregnancy, no relevant family or personal history, in which the prenatal fetal ultrasound performed at 19 weeks of gestation revealed an anterior abdominal wall defect with exteriorisation of the heart and exencephaly. The pregnancy was terminated after counselling parents with baby weighing 119 gm. Sonographic findings were confirmed on post-natal examination.
Vaginal leiomyoma in a post menopausal woman
Authors: Jayaram Surya , Mayadevi Sarojini
Published: March 2021

Leiomyomas or fibroids are the commonest gynaecological tumours. It is only very rarely reported as vaginal lesion. It is usually treated by excision of the lesion. This is an interesting case of a 72-year-old lady who presented with vaginal pain and found to have a firm, mobile mass of 4cms x 5cms size located in the middle third of anterior wall of vagina. MRI showed a well-encapsulated solid, round mass with peripheral enhancement localised to anterior vaginal wall. This mass was removed vaginally under anaesthesia. Histopathologic examination of the mass showed leiomyoma.
Molar pregnancy with false negative urine pregnancy test, the hook effect
Authors: Gupta Bhavana
Published: March 2021

Molar pregnancy is characterized by high level of serum β hcg which can be usually detected by urine pregnancy test as a first screening test. Urine pregnancy test is also used as the first screening test for patients of reproductive age presenting with gynecological problem in order to exclude pregnancy. Rarely large amounts of β human chorionic gonadotrophin (hcg) may cause a false negative result due to over saturation of the assay system, known as, ‘the hook effect’. This can result clinical dilemma in the diagnosis and delay in the management. When there is clinical features of molar pregnancy, the knowledge of “The Hook Effect” will help at arriving at the diagnosis.