bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 1 from FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth
Authors: Du Xiangnan , Wang Qian-Rena , Chan Emily , Merchant Mark , Liu Jinfeng , French Dorothy , Ashkenazi Avi , Qing Jing
Published: April 2023

XLS file - 97KB, List of genes that showed significant changes upon FGFR3 knockdown.
Supplementary Methods and Materials and Figure Legends from FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth
Authors: Du Xiangnan , Wang Qian-Rena , Chan Emily , Merchant Mark , Liu Jinfeng , French Dorothy , Ashkenazi Avi , Qing Jing
Published: April 2023

PDF file, 114KB, This section includes Supplemental Materials and Methods. It also contains the legends to Supplemental Figures 1-9.
Supplementary Figures 1-9 and Supplementary Table 2 from FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth
Authors: Du Xiangnan , Wang Qian-Rena , Chan Emily , Merchant Mark , Liu Jinfeng , French Dorothy , Ashkenazi Avi , Qing Jing
Published: April 2023

PDF file - 800KB, Figure S1 Identification of FGFR3-regulated genes. Figure S2 FGFR3 knockdown in RT112 bladder cancer cells reduces the expression of genes involved in sterol and fatty acid biosynthesis and metabolism. Figure S3 Inhibition of FGFR3 reduces the expression of genes involved in sterol and fatty acid biosynthesis and metabolism in UMUC-14 cells. Figure S4 FGF1 stimulates SREBP1 activation and lipogenesis in bladder cancer cells. Figure S5 FGFR3 signaling promotes the accumulation of matured SREBP1 and SCD1 expression via PI3K-mTORC1 pathway but not MEK-MAPK pathway in Cal29 cells. Figure S6 SCD1 knockdown induces apoptosis in bladder cancer cells. (A) FGFR3 signaling in SW780 bladder cancer cells. Figure S7 SCD1 knockdown inhibits bladder cancer cell proliferation in a fatty acid desaturation-dependent manner. Figure S8 SCD1 inhibitor suppresses cell proliferation in a fatty acid desaturation-dependent manner in SW780 cells. Figure S9 SCD1 inhibitor A37062 activates caspase 3 in UMUC-14 xenograft tumors.Supplemental Table 2 Mutational status of FGFR3 and pathway activity in bladder cancer cell lines
Supplementary Figure Legends 1-3 from Cytomegalovirus Infection Leads to Pleomorphic Rhabdomyosarcomas in Trp53+/− Mice
Authors: Price Richard L. , Bingmer Katherine , Harkins Lualhati , Iwenofu O. Hans , Kwon Chang-Hyuk , Cook Charles , Pelloski Christopher , Chiocca E. Antonio
Published: April 2023

PDF file - 77K
Supplementary Table 2 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer
Authors: Nikolaidis Georgios , Raji Olaide Y. , Markopoulou Soultana , Gosney John R. , Bryan Julie , Warburton Chris , Walshaw Martin , Sheard John , Field John K. , Liloglou Triantafillos
Published: April 2023

PDF file - 46K, Statistical Power Simulation for the estimating the bronchial washing study size
Supplementary Figure 2 from Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion
Authors: Ferrari-Amorotti Giovanna , Fragliasso Valentina , Esteki Roza , Prudente Zelia , Soliera Angela Rachele , Cattelani Sara , Manzotti Gloria , Grisendi Giulia , Dominici Massimo , Pieraccioli Marco , Raschellà Giuseppe , Chiodoni Claudia , Colombo Mario Paolo , Calabretta Bruno
Published: April 2023

PDF file - 153K, Effect of LSD1 silencing on migration and invasion of HCT116 cells
Supplementary Table 5 from An Integrated Genome-Wide Approach to Discover Tumor-Specific Antigens as Potential Immunologic and Clinical Targets in Cancer
Authors: Xu Qing-Wen , Zhao Wei , Wang Yue , Sartor Maureen A. , Han Dong-Mei , Deng Jixin , Ponnala Rakesh , Yang Jiang-Ying , Zhang Qing-Yun , Liao Guo-Qing , Qu Yi-Mei , Li Lu , Liu Fang-Fang , Zhao Hong-Mei , Yin Yan-Hui , Chen Wei-Feng , Zhang Yu , Wang Xiao-Song
Published: April 2023

PDF file - 56K, Age and sex distribution of the lung patient and healthy cohorts, and the autoantibody responses in lung cancer patients at different clinical stages
Supplementary Figure S1 from Hypoxia Triggers Hedgehog-Mediated Tumor–Stromal Interactions in Pancreatic Cancer
Authors: Spivak-Kroizman Taly R. , Hostetter Galen , Posner Richard , Aziz Meraj , Hu Chengcheng , Demeure Michael J. , Von Hoff Daniel , Hingorani Sunil R. , Palculict Timothy B. , Izzo Julie , Kiriakova Galina M. , Abdelmelek Mena , Bartholomeusz Geoffrey , James Brian P. , Powis Garth
Published: April 2023

Figure S1 - PDF file 65K, Specificity of SHH antibodies to SHH vs. IHH and DHH
Supplementary Figure 7 from Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling
Authors: Liu Yu-Peng , Yang Chih-Jen , Huang Ming-Shyan , Yeh Chi-Tai , Wu Alexander T.H. , Lee Yu-Cheng , Lai Tsung-Ching , Lee Chien-Hsin , Hsiao Ya-Wen , Lu Jean , Shen Chia-Ning , Lu Pei-Jung , Hsiao Michael
Published: April 2023

PDF file - 138K, The role of Notch signaling in enrichment of CD133+ cells and multi-drug resistance of H661 cells
Supplementary Figure 4 from Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling
Authors: Liu Yu-Peng , Yang Chih-Jen , Huang Ming-Shyan , Yeh Chi-Tai , Wu Alexander T.H. , Lee Yu-Cheng , Lai Tsung-Ching , Lee Chien-Hsin , Hsiao Ya-Wen , Lu Jean , Shen Chia-Ning , Lu Pei-Jung , Hsiao Michael
Published: April 2023

PDF file - 139K, Enrichment of ALDH+ cells by cisplatin treatment
Supplementary Figure 3 from Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling
Authors: Liu Yu-Peng , Yang Chih-Jen , Huang Ming-Shyan , Yeh Chi-Tai , Wu Alexander T.H. , Lee Yu-Cheng , Lai Tsung-Ching , Lee Chien-Hsin , Hsiao Ya-Wen , Lu Jean , Shen Chia-Ning , Lu Pei-Jung , Hsiao Michael
Published: April 2023

PDF file - 289K, Carboplatin induced DNA damage and CD133+ cell enrichment
Supplementary Figure 6 from Roles for Endothelin Receptor B and BCL2A1 in Spontaneous CNS Metastasis of Melanoma
Authors: Cruz-Muñoz William , Jaramillo Maria L. , Man Shan , Xu Ping , Banville Myriam , Collins Catherine , Nantel Andre , Francia Giulio , Morgan Sherif S. , Cranmer Lee D. , O'Connor-McCourt Maureen D. , Kerbel Robert S.
Published: April 2023

PDF file - 108K, Confirmation of ET1 and ET3 expression in brain and lung
Supplementary Figure 1 from Functional Genomics Identifies Drivers of Medulloblastoma Dissemination
Authors: Mumert Michael , Dubuc Adrian , Wu Xiaochong , Northcott Paul A. , Chin Steven S. , Pedone Carolyn A. , Taylor Michael D. , Fults Daniel W.
Published: April 2023

PDF file - 112K, Expression of CCRK and LHX1 in an independent set of human medulloblastomas. Box plots showing relative expression of CCRK (A), and LHX1 (B) in normal cerebella (CB; n=11) and medulloblastoma samples (MB; n=187) profiled on Affymetrix exon arrays
Supplementary Table 3 from Detection of Redundant Fusion Transcripts as Biomarkers or Disease-Specific Therapeutic Targets in Breast Cancer
Authors: Asmann Yan W. , Necela Brian M. , Kalari Krishna R. , Hossain Asif , Baker Tiffany R. , Carr Jennifer M. , Davis Caroline , Getz Julie E. , Hostetter Galen , Li Xing , McLaughlin Sarah A. , Radisky Derek C. , Schroth Gary P. , Cunliffe Heather E. , Perez Edith A. , Thompson E. Aubrey
Published: April 2023

Supplementary Table 3 from Detection of Redundant Fusion Transcripts as Biomarkers or Disease-Specific Therapeutic Targets in Breast Cancer
Supplementary Table 1 from Galectin-3 Contributes to Melanoma Growth and Metastasis via Regulation of NFAT1 and Autotaxin
Authors: Braeuer Russell R. , Zigler Maya , Kamiya Takafumi , Dobroff Andrey S. , Huang Li , Choi Woonyoung , McConkey David J. , Shoshan Einav , Mobley Aaron K. , Song Renduo , Raz Avraham , Bar-Eli Menashe
Published: April 2023

PDF file, 61K, Oligos used for experiments
Supplementary Table 1 from Detection of Redundant Fusion Transcripts as Biomarkers or Disease-Specific Therapeutic Targets in Breast Cancer
Authors: Asmann Yan W. , Necela Brian M. , Kalari Krishna R. , Hossain Asif , Baker Tiffany R. , Carr Jennifer M. , Davis Caroline , Getz Julie E. , Hostetter Galen , Li Xing , McLaughlin Sarah A. , Radisky Derek C. , Schroth Gary P. , Cunliffe Heather E. , Perez Edith A. , Thompson E. Aubrey
Published: April 2023

Supplementary Table 1 from Detection of Redundant Fusion Transcripts as Biomarkers or Disease-Specific Therapeutic Targets in Breast Cancer
Supplementary Table 1 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 62K
Supplementary Methods from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 131K
Supplementary Figure 7 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 1.8MB
Supplementary Figure 6 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 376K
Supplementary Table 1 from NEDD9 Depletion Destabilizes Aurora A Kinase and Heightens the Efficacy of Aurora A Inhibitors: Implications for Treatment of Metastatic Solid Tumors
Authors: Ice Ryan J. , McLaughlin Sarah L. , Livengood Ryan H. , Culp Mark V. , Eddy Erik R. , Ivanov Alexey V. , Pugacheva Elena N.
Published: April 2023

Supplementary Table 1 - PDF file 26K
Supplementary Figure 2 from NEDD9 Depletion Destabilizes Aurora A Kinase and Heightens the Efficacy of Aurora A Inhibitors: Implications for Treatment of Metastatic Solid Tumors
Authors: Ice Ryan J. , McLaughlin Sarah L. , Livengood Ryan H. , Culp Mark V. , Eddy Erik R. , Ivanov Alexey V. , Pugacheva Elena N.
Published: April 2023

Supplementary Figure 2 - PDF file 143K
Supplementary Figure 4 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 260K
Supplementary Figure 3 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 1MB
Supplementary Figure 2 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 549K
Supplementary Figure 1 from Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Authors: Brahimi-Horn M. Christiane , Ben-Hail Danya , Ilie Marius , Gounon Pierre , Rouleau Matthieu , Hofman Véronique , Doyen Jérôme , Mari Bernard , Shoshan-Barmatz Varda , Hofman Paul , Pouysségur Jacques , Mazure Nathalie M.
Published: April 2023

PDF file - 105K
Supplementary Figures 1-6 from T-Cell Trafficking Facilitated by High Endothelial Venules Is Required for Tumor Control after Regulatory T-Cell Depletion
Authors: Hindley James P. , Jones Emma , Smart Kathryn , Bridgeman Hayley , Lauder Sarah N. , Ondondo Beatrice , Cutting Scott , Ladell Kristin , Wynn Katherine K. , Withers David , Price David A. , Ager Ann , Godkin Andrew J. , Gallimore Awen M.
Published: April 2023

PDF file - 234K, S Figure 1 - Levels of Foxp3+ Tregs and T cell activation following various doses of DT treatment. S Figure 2 - Efficient depletion of Foxp3+ Tregs leads to T cell activation and proliferation. S Figure 3 - T cell accumulation in tumors of DT treated mice. S Figure 4 - Reduced tumor growth rate following depletion of Foxp3+ Tregs does not correlate with the extent of T cell activation S Figure 5 - Treg-HEV+ tumors do not contain LTi cells. S Figure 6 - Restriction of TCR repertoire in a tumor of DT treated mouse
Supplementary Table 2 from Genetically Mediated Nf1 Loss in Mice Promotes Diverse Radiation-Induced Tumors Modeling Second Malignant Neoplasms
Authors: Choi Grace , Huang Brian , Pinarbasi Emile , Braunstein Steve E. , Horvai Andrew E. , Kogan Scott , Bhatia Smita , Faddegon Bruce , Nakamura Jean L.
Published: April 2023

PDF file - 35K, Trp53 exon sequencing primers
Supplementary Figure 4 from IFNβ Produced by TLR4-Activated Tumor Cells Is Involved in Improving the Antitumoral Immune Response
Authors: Núñez Nicolás Gonzalo , Andreani Virginia , Crespo María Inés , Nocera David Andrés , Breser María Laura , Morón Gabriel , Dejager Lien , Libert Claude , Rivero Virginia , Maccioni Mariana
Published: April 2023

PDF file - 165K
Supplementary Figure 3 from IFNβ Produced by TLR4-Activated Tumor Cells Is Involved in Improving the Antitumoral Immune Response
Authors: Núñez Nicolás Gonzalo , Andreani Virginia , Crespo María Inés , Nocera David Andrés , Breser María Laura , Morón Gabriel , Dejager Lien , Libert Claude , Rivero Virginia , Maccioni Mariana
Published: April 2023

PDF file - 71K
Supplementary Figure 2 from IFNβ Produced by TLR4-Activated Tumor Cells Is Involved in Improving the Antitumoral Immune Response
Authors: Núñez Nicolás Gonzalo , Andreani Virginia , Crespo María Inés , Nocera David Andrés , Breser María Laura , Morón Gabriel , Dejager Lien , Libert Claude , Rivero Virginia , Maccioni Mariana
Published: April 2023

PDF file - 70K
Supplementary Figure Legends 1-3 from Genetically Mediated Nf1 Loss in Mice Promotes Diverse Radiation-Induced Tumors Modeling Second Malignant Neoplasms
Authors: Choi Grace , Huang Brian , Pinarbasi Emile , Braunstein Steve E. , Horvai Andrew E. , Kogan Scott , Bhatia Smita , Faddegon Bruce , Nakamura Jean L.
Published: April 2023

PDF file - 63K
Supplementary Figure 1 from IFNβ Produced by TLR4-Activated Tumor Cells Is Involved in Improving the Antitumoral Immune Response
Authors: Núñez Nicolás Gonzalo , Andreani Virginia , Crespo María Inés , Nocera David Andrés , Breser María Laura , Morón Gabriel , Dejager Lien , Libert Claude , Rivero Virginia , Maccioni Mariana
Published: April 2023

PDF - 114K
Supplementary Figure 3 from Genetically Mediated Nf1 Loss in Mice Promotes Diverse Radiation-Induced Tumors Modeling Second Malignant Neoplasms
Authors: Choi Grace , Huang Brian , Pinarbasi Emile , Braunstein Steve E. , Horvai Andrew E. , Kogan Scott , Bhatia Smita , Faddegon Bruce , Nakamura Jean L.
Published: April 2023

PDF file - 227K, Taqman Real-Time PCR Data for NF1 genotyping
Supplementary Figure 1 from Genetically Mediated Nf1 Loss in Mice Promotes Diverse Radiation-Induced Tumors Modeling Second Malignant Neoplasms
Authors: Choi Grace , Huang Brian , Pinarbasi Emile , Braunstein Steve E. , Horvai Andrew E. , Kogan Scott , Bhatia Smita , Faddegon Bruce , Nakamura Jean L.
Published: April 2023

PDF file - 678K, Abdominal Irradiation set up
Supplementary Figure 3 from PDGF Receptor Alpha Is an Alternative Mediator of Rapamycin-Induced Akt Activation: Implications for Combination Targeted Therapy of Synovial Sarcoma
Authors: Ho Alan L. , Vasudeva Shyamprasad Deraje , Laé Marick , Saito Tsuyoshi , Barbashina Violetta , Antonescu Cristina R. , Ladanyi Marc , Schwartz Gary K.
Published: April 2023

PDF file - 220K, Rapamycin decreases IRS-1 phosphorylation and Grb10 levels in HS-SY-II cells, but not SYO-1 cells; western blots evaluating changes in IRS-1 phosphorylation and Grb10 levels with rapamycin treatment
Supplementary Figure 6 from miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma
Authors: Wei Jun , Wang Fei , Kong Ling-Yuan , Xu Shuo , Doucette Tiffany , Ferguson Sherise D. , Yang Yuhui , McEnery Kayla , Jethwa Krishan , Gjyshi Olsi , Qiao Wei , Levine Nicholas B. , Lang Frederick F. , Rao Ganesh , Fuller Gregory N. , Calin George A. , Heimberger Amy B.
Published: April 2023

Supplementary Figure 6 - PDF file 131K,viR-124 modulates Th1, Th17, and inducible Treg differentiation. CD4+CD45RA+CD45RO-na�ve T-cells were isolated from healthy donor PBMCs and stimulated with plate-bound anti-CD3 and soluble anti-CD28 under Th1, Th17, and inducible 3 Treg polarization conditions before miR-124 transfection. After 3 rounds of T-cell stimulation and polarization, cytokine production in the different Th populations was quantified by intracellular cytokine FACS. One representative se t of data was shown, but similar results were obtained from two additional independent experiments
Supplementary Figure 3 from miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma
Authors: Wei Jun , Wang Fei , Kong Ling-Yuan , Xu Shuo , Doucette Tiffany , Ferguson Sherise D. , Yang Yuhui , McEnery Kayla , Jethwa Krishan , Gjyshi Olsi , Qiao Wei , Levine Nicholas B. , Lang Frederick F. , Rao Ganesh , Fuller Gregory N. , Calin George A. , Heimberger Amy B.
Published: April 2023

Supplementary Figure 3 - PDF file 37K, miR-21 expression is higher in gCSCs and glioblastoma tumors than in normal brain and is inhibited by miR-124 overexpression. (A) Relative expression levels of miR-21 were detected by TaqMan quantitative P CR. There were significant differences in the relative expression levels of miR-21 between normal brain tissues, gCSCs and GBM specimens. (B) T-cell proliferation was detected by flow cytometry analysis with CFSE staining after 3 days of treatment with medium alone, gCSC-scramble-transfected conditioned medium, or gCSC-miR-21-transfected conditioned medi um. miR-21 up regulation caused further inhibition in T-cell proliferation compared with the gCSC-scramble-transfected conditioned medium. (C) Forced overexpression of miR-124 in the gCSCs resulted in the down modulation of miR-21 expression
Supplementary Figure Legends 1-5 from A Single-Nucleotide Substitution Mutator Phenotype Revealed by Exome Sequencing of Human Colon Adenomas
Authors: Nikolaev Sergey I. , Sotiriou Sotirios K. , Pateras Ioannis S. , Santoni Federico , Sougioultzis Stavros , Edgren Henrik , Almusa Henrikki , Robyr Daniel , Guipponi Michel , Saarela Janna , Gorgoulis Vassilis G. , Antonarakis Stylianos E. , Halazonetis Thanos D.
Published: April 2023

PDF file - 60K
Supplementary Figure 2 from miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma
Authors: Wei Jun , Wang Fei , Kong Ling-Yuan , Xu Shuo , Doucette Tiffany , Ferguson Sherise D. , Yang Yuhui , McEnery Kayla , Jethwa Krishan , Gjyshi Olsi , Qiao Wei , Levine Nicholas B. , Lang Frederick F. , Rao Ganesh , Fuller Gregory N. , Calin George A. , Heimberger Amy B.
Published: April 2023

Supplementary Figure 2 - PDF file 25K, Schema demonstrating how miR-124 exerts target effects on the STAT3 pathway in gCSC cells. STAT3 can be activated by a variety of ligands such as IL-6 or EGFR. miR-124 can not only down-modulate SHC1, STAT3, P-STAT3 in all tested gCSC cell lines but also, occasionally, pMAPK1/3, probably in a contextual fashion when the IL-6R ligand is not present and the gCSC is dependent on EGFR signaling
Supplementary Figure 2 from Genome-Wide Association Study of Genetic Predictors of Overall Survival for Non–Small Cell Lung Cancer in Never Smokers
Authors: Wu Xifeng , Wang Liang , Ye Yuanqing , Aakre Jeremiah A. , Pu Xia , Chang Gee-Chen , Yang Pan-Chyr , Roth Jack A. , Marks Randolph S. , Lippman Scott M. , Chang Joe Y. , Lu Charles , Deschamps Claude , Su Wu-Chou , Wang Wen-Chang , Huang Ming-Shyan , Chang David W. , Li Yan , Pankratz V. Shane , Minna John D. , Hong Waun Ki , Hildebrandt Michelle A.T. , Hsiung Chao Agnes , Yang Ping
Published: April 2023

PDF file - 57K, Q-Q plot.
Supplementary Methods and Figure Legend from NLRR1 Enhances EGF-Mediated MYCN Induction in Neuroblastoma and Accelerates Tumor Growth In Vivo
Authors: Hossain Shamim , Takatori Atsushi , Nakamura Yohko , Suenaga Yusuke , Kamijo Takehiko , Nakagawara Akira
Published: April 2023

PDF file, 90K.
Supplementary Figure 1 from NLRR1 Enhances EGF-Mediated MYCN Induction in Neuroblastoma and Accelerates Tumor Growth In Vivo
Authors: Hossain Shamim , Takatori Atsushi , Nakamura Yohko , Suenaga Yusuke , Kamijo Takehiko , Nakagawara Akira
Published: April 2023

PDF file, 103K, EGF-mediated phosphorylation of EGFR and ERK. EGF stimulation enhances EGFR phosphorylation in the cells. U0126 and AG1478 effectively inhibit EGF-mediated phosphorylation of ERK and EGFR, respectively.
Supplementary Table 6 from Characterization of Gene–Environment Interactions for Colorectal Cancer Susceptibility Loci
Authors: Hutter Carolyn M. , Chang-Claude Jenny , Slattery Martha L. , Pflugeisen Bethann M. , Lin Yi , Duggan David , Nan Hongmei , Lemire Mathieu , Rangrej Jagadish , Figueiredo Jane C. , Jiao Shuo , Harrison Tabitha A. , Liu Yan , Chen Lin S. , Stelling Deanna L. , Warnick Greg S. , Hoffmeister Michael , Küry Sébastien , Fuchs Charles S. , Giovannucci Edward , Hazra Aditi , Kraft Peter , Hunter David J. , Gallinger Steven , Zanke Brent W. , Brenner Hermann , Frank Bernd , Ma Jing , Ulrich Cornelia M. , White Emily , Newcomb Polly A. , Kooperberg Charles , LaCroix Andrea Z. , Prentice Ross L. , Jackson Rebecca D. , Schoen Robert E. , Chanock Stephen J. , Berndt Sonja I. , Hayes Richard B. , Caan Bette J. , Potter John D. , Hsu Li , Bézieau Stéphane , Chan Andrew T. , Hudson Thomas J. , Peters Ulrike
Published: April 2023

PDF file - 55K, Further information about main finding
Supplementary Methods from RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development
Authors: Yin Zhengyu , Menendez Daniel , Resnick Michael A. , French John E. , Janardhan Kyathanahalli S. , Jetten Anton M.
Published: April 2023

PDF file - 96K, Generation of RAP80 null Mice and Real-time qRT-PCR analysis
Supplementary Table 3 from Characterization of Gene–Environment Interactions for Colorectal Cancer Susceptibility Loci
Authors: Hutter Carolyn M. , Chang-Claude Jenny , Slattery Martha L. , Pflugeisen Bethann M. , Lin Yi , Duggan David , Nan Hongmei , Lemire Mathieu , Rangrej Jagadish , Figueiredo Jane C. , Jiao Shuo , Harrison Tabitha A. , Liu Yan , Chen Lin S. , Stelling Deanna L. , Warnick Greg S. , Hoffmeister Michael , Küry Sébastien , Fuchs Charles S. , Giovannucci Edward , Hazra Aditi , Kraft Peter , Hunter David J. , Gallinger Steven , Zanke Brent W. , Brenner Hermann , Frank Bernd , Ma Jing , Ulrich Cornelia M. , White Emily , Newcomb Polly A. , Kooperberg Charles , LaCroix Andrea Z. , Prentice Ross L. , Jackson Rebecca D. , Schoen Robert E. , Chanock Stephen J. , Berndt Sonja I. , Hayes Richard B. , Caan Bette J. , Potter John D. , Hsu Li , Bézieau Stéphane , Chan Andrew T. , Hudson Thomas J. , Peters Ulrike
Published: April 2023

PDF file - 67K, Descriptives for smoking, BMI, height, dietary variables, alcohol, sex, and NSAID use.
Supplementary Figure 6 from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 1437K, Supplemental Figure 6. Wnt signaling is inhibited by the OMP-18R5 therapeutic.
Supplementary Figure 1 from Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI
Authors: Halle Cathinka , Andersen Erlend , Lando Malin , Aarnes Eva-Katrine , Hasvold Grete , Holden Marit , Syljuåsen Randi G. , Sundfør Kolbein , Kristensen Gunnar B. , Holm Ruth , Malinen Eirik , Lyng Heidi
Published: April 2023

PDF file - 34K, Prognostic significance of DCE-MRI parameters kep and kel
Supplementary Figure 4 from Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy
Authors: Ramakrishnan Rupal , Huang Chun , Cho Hyun-Il , Lloyd Mark , Johnson Joseph , Ren Xiubao , Altiok Soner , Sullivan Daniel , Weber Jeffrey , Celis Esteban , Gabrilovich Dmitry I.
Published: April 2023

PDF file - 39K, Redistribution of MPR to the cell surface after chemotherapy
Supplementary Figure S1 from Radioresistant Cancer Cells Can Be Conditioned to Enter Senescence by mTOR Inhibition
Authors: Nam Hae Yun , Han Myung Woul , Chang Hyo Won , Lee Yoon Sun , Lee Myungjin , Lee Hyang Ju , Lee Byoung Wook , Lee Hee Jin , Lee Kyung Eun , Jung Min Kyo , Jeon Hyesung , Choi Seung-Ho , Park Neung Hwa , Kim Sang Yoon , Kim Seong Who
Published: April 2023

Supplementary Figure S1 - PDF file 214K, Clonogenic survival of cancer cell lines
Supplementary Figure 1 from Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy
Authors: Ramakrishnan Rupal , Huang Chun , Cho Hyun-Il , Lloyd Mark , Johnson Joseph , Ren Xiubao , Altiok Soner , Sullivan Daniel , Weber Jeffrey , Celis Esteban , Gabrilovich Dmitry I.
Published: April 2023

PDF file - 86K, The effect of chemotherapy on expression of MPR in vivo
Supplementary Figure 6 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 57K
Supplementary Figure 4 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 56K
Supplementary Figure 2 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 2.8MB
Supplementary Figure 1 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 2.3MB
Supplementary Figure 4 from CD73-Deficient Mice Are Resistant to Carcinogenesis
Authors: Stagg John , Beavis Paul A. , Divisekera Upulie , Liu Mira C.P. , Möller Andreas , Darcy Phillip K. , Smyth Mark J.
Published: April 2023

PDF file - 3.5MB
Supplementary Figure 8 from HMGA2 Is a Driver of Tumor Metastasis
Authors: Morishita Asahiro , Zaidi M. Raza , Mitoro Akira , Sankarasharma Devipriya , Szabolcs Matthias , Okada Yasunori , D'Armiento Jeanine , Chada Kiran
Published: April 2023

Supplementary Figure 8 - PDF file 82K, There is no statistically significant difference in Snail and Twist mRNA expression in ectopic HMGA2 transfected cells (MCF7-HMGA2 cells)
Supplementary Figure 7 from HMGA2 Is a Driver of Tumor Metastasis
Authors: Morishita Asahiro , Zaidi M. Raza , Mitoro Akira , Sankarasharma Devipriya , Szabolcs Matthias , Okada Yasunori , D'Armiento Jeanine , Chada Kiran
Published: April 2023

Supplementary Figure 7 - PDF file 97K, Schematic of liver metastasis. Metastatic cancer cells (4TO7 cells stably over-expressing HMGA2 and 4T1 cells) are located in Glisson's capsule (GC) and Liver parenchyma (LP)
Supplementary Figure 6 from HMGA2 Is a Driver of Tumor Metastasis
Authors: Morishita Asahiro , Zaidi M. Raza , Mitoro Akira , Sankarasharma Devipriya , Szabolcs Matthias , Okada Yasunori , D'Armiento Jeanine , Chada Kiran
Published: April 2023

Supplementary Figure 6 - PDF file 132K, (A) HMGA2 was detected at the edge of the metastatic lung tumor (left, arrows) and from the vessel of the liver stroma to the parenchyma in the metastatic liver tumor (right, arrows). Scale bars represent 100 microm. (B) Liver metastases (arrows) were induced in 4TO7 cells stably over-expressing HMGA2 (4TO7-HMGA2)
Supplementary Figure 1 from Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors
Authors: Duraiswamy Jaikumar , Kaluza Karen M. , Freeman Gordon J. , Coukos George
Published: April 2023

Supplementary Figure 1 - PDF file 56K, Splenic T cells in CT26-bearing mice express low levels of PD-1 or CTLA-4. Representative and summary data showing the frequency of PD-1 and CTLA-4 expression on CD8+ (A) and CD4+ (B) T cells from spleen of CT26 tumor bearing mice
Supplementary Figure 5 from Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Authors: Hu Bin , Nandhu Mohan S. , Sim Hosung , Agudelo-Garcia Paula A. , Saldivar Joshua C. , Dolan Claire E. , Mora Maria E. , Nuovo Gerard J. , Cole Susan E. , Viapiano Mariano S.
Published: April 2023

PDF file - 451K, Fibulin-3 knockdown slows cell growth and increases cell death
Supplementary Figure 1 from Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Authors: Hu Bin , Nandhu Mohan S. , Sim Hosung , Agudelo-Garcia Paula A. , Saldivar Joshua C. , Dolan Claire E. , Mora Maria E. , Nuovo Gerard J. , Cole Susan E. , Viapiano Mariano S.
Published: April 2023

PDF file - 473K, Conservation of the DSL motif in fibulin-3 and canonical Notch ligands
Supplementary Methods from Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State
Authors: Teng Michele W. L. , Vesely Matthew D. , Duret Helene , McLaughlin Nicole , Towne Jennifer E. , Schreiber Robert D. , Smyth Mark J.
Published: April 2023

PDF file - 70K, Methods include mice info, tumor models, MAbs and cell depletions, and statistical analysis
Supplementary Figure Legends 1-5 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: April 2023

PDF file - 19K
Supplementary Figure Legends and Materials and Methods and Tables 1-5 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 155K, Supplementary Table 1: Antibodies used for FACS sorting. Supplementary Table 2: Antibodies used for IHC. Supplementary Table 3: Primers used for QPCR. Supplementary Table 4: Antibodies used for Western blotting.Supplementary Table 5: Primers used for Methylation Specific. PCR
Supplementary Figure 6 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 130K, Analysis of epithelial and stromal populations from PTENKO and PTENKO/Kras tumors.
Supplementary Figure 3 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 183K, Measurement of proliferative index and ER � expression in PTENKO tumors treated under different hormonal conditions.
Supplementary Figure 3 from Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation
Authors: Yi Lan , Lu Chiwei , Hu Wenwei , Sun Yvonne , Levine Arnold J.
Published: April 2023

PDF file - 88K, Different from P53, P63 and P73 were not directly involved in iPSC generation.
Supplementary Figure 1 from Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation
Authors: Yi Lan , Lu Chiwei , Hu Wenwei , Sun Yvonne , Levine Arnold J.
Published: April 2023

PDF file - 14.9MB, Loss of P53 expedited the kinetics of MEF cell reprogramming
Supplementary Figure Legends 1-6, Table Legends 1-2 from ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Authors: Faget Julien , Bendriss-Vermare Nathalie , Gobert Michael , Durand Isabelle , Olive Daniel , Biota Cathy , Bachelot Thomas , Treilleux Isabelle , Goddard-Leon Sophie , Lavergne Emilie , Chabaud Sylvie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: April 2023

PDF file - 68K
Supplementary Figure Legends 1-4 from Tumor-Derived Chemokine CCL5 Enhances TGF-β–Mediated Killing of CD8+ T Cells in Colon Cancer by T-Regulatory Cells
Authors: Chang Li-Yuan , Lin Yung-Chang , Mahalingam Jayashri , Huang Ching-Tai , Chen Ten-Wen , Kang Chiao-Wen , Peng Hui-Min , Chu Yu-Yi , Chiang Jy-Ming , Dutta Avijit , Day Yuan-Ji , Chen Tse-Ching , Yeh Chau-Ting , Lin Chun-Yen
Published: April 2023

PDF file - 96K
Supplementary Table 2 from Exploiting the Mutanome for Tumor Vaccination
Authors: Castle John C. , Kreiter Sebastian , Diekmann Jan , Löwer Martin , van de Roemer Niels , de Graaf Jos , Selmi Abderraouf , Diken Mustafa , Boegel Sebastian , Paret Claudia , Koslowski Michael , Kuhn Andreas N. , Britten Cedrik M. , Huber Christoph , Türeci Özlem , Sahin Ugur
Published: April 2023

XLS file - 56K
Supplementary Figure 8 from Cardiac Inflammation after Local Irradiation Is Influenced by the Kallikrein-Kinin System
Authors: Sridharan Vijayalakshmi , Tripathi Preeti , Sharma Sunil K. , Moros Eduardo G. , Corry Peter M. , Lieblong Benjamin J. , Kaschina Elena , Unger Thomas , Thöne-Reineke Christa , Hauer-Jensen Martin , Boerma Marjan
Published: April 2023

PDF file - 163K, Western-Blot analysis of c-Jun at 3 months after sham-irradiation or local heart irradiation with 24 Gy
Supplementary Table 1 from Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein–Coupled Receptor
Authors: Aguilar Berenice , Choi Inho , Choi Dongwon , Chung Hee Kyoung , Lee Sunju , Yoo Jaehyuk , Lee Yong Suk , Maeng Yong Sun , Lee Ha Neul , Park Eunkyung , Kim Kyu Eui , Kim Nam Yoon , Baik Jae Myung , Jung Jae U. , Koh Chester J. , Hong Young-Kwon
Published: April 2023

PDF file - 91K, Regulation of the expression of the RGS genes by KSHV in BECs
Supplementary Figures 1-4 from Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein–Coupled Receptor
Authors: Aguilar Berenice , Choi Inho , Choi Dongwon , Chung Hee Kyoung , Lee Sunju , Yoo Jaehyuk , Lee Yong Suk , Maeng Yong Sun , Lee Ha Neul , Park Eunkyung , Kim Kyu Eui , Kim Nam Yoon , Baik Jae Myung , Jung Jae U. , Koh Chester J. , Hong Young-Kwon
Published: April 2023

PDF file - 491K, Supplemental Figure 1. Absence of RGS4 expression in KS tumor cells. Supplemental Figure 2. Blood vessel-specific expression of RGS4. Supplemental Figure 3. Morphometric vascular analyses of control and RGS4-expressing tumors of similar sizes that were harvested at various time points from NSG mice. Supplemental Figure 4. Expression of blood- and lymphatic-signature genes in SVECs and derivative cells.
Supplementary Figure 5 from Estrogen Receptor Alpha Mediates Progestin-Induced Mammary Tumor Growth by Interacting with Progesterone Receptors at the Cyclin D1/MYC Promoters
Authors: Giulianelli Sebastián , Vaqué José P. , Soldati Rocío , Wargon Victoria , Vanzulli Silvia I. , Martins Rubén , Zeitlin Eduardo , Molinolo Alfredo A. , Helguero Luisa A. , Lamb Caroline A. , Gutkind J. Silvio , Lanari Claudia
Published: April 2023

PDF file - 160K, ER� increase PR activity. MDA-MB-231 cells were stably transfected with human PRB (pSG5-PRB) or with the empty vector (pSG5) and different clones were obtained. The expression of PRB was evaluated by Western blot (A), using T47D cells as a positive control of hormone receptors, or by immunofluorescence (B, bar: 30�m). (C) MDA-MB-231 pSG5 clone (3) and pSG5-PRB clone (1) cells were transiently transfected with human ER� (pSG5-HEGO) and its expression was evaluated by immnunofluorescence. Bar: 15�m. (D) MDA-MB-231 pSG5 clone (3) and pSG5-PRB clone (1) cells were co-transfected with ER� and PRE-Luc vectors. After 24 h starvation in 1% chFCS, cells were incubated with MPA for another 24 h and the activity of luciferase was evaluated.
Supplementary Figure 5 from Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor
Authors: Cavel Oren , Shomron Olga , Shabtay Ayelet , Vital Joseph , Trejo-Leider Leonor , Weizman Noam , Krelin Yakov , Fong Yuman , Wong Richard J. , Amit Moran , Gil Ziv
Published: April 2023

PDF file - 25K, The effect of PYP1 on the PDA cells proliferation. As revealed by XTT assay, PYP1 (2mum) had no effect on cancer cell proliferation induced by the EMPhi conditioned media.
Supplementary Figure 3 from Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor
Authors: Cavel Oren , Shomron Olga , Shabtay Ayelet , Vital Joseph , Trejo-Leider Leonor , Weizman Noam , Krelin Yakov , Fong Yuman , Wong Richard J. , Amit Moran , Gil Ziv
Published: April 2023

PDF file - 178K, Scratch assays of MiaPaCa2 cells in the presence or absence of EMPhi-CM. (a) Representative pictures taken after 24 and 48 hours showing increased motility of cancer cells incubated with EMPhi-CM (lower row) relative to normal medium (DMEM- upper row). (b) Summary of the data showing statistically significant increase in cancer cell motility after incubation in EMPhi-CM compared to normal media (n=6, P<0.001).
Supplementary Figure 2 from Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor
Authors: Cavel Oren , Shomron Olga , Shabtay Ayelet , Vital Joseph , Trejo-Leider Leonor , Weizman Noam , Krelin Yakov , Fong Yuman , Wong Richard J. , Amit Moran , Gil Ziv
Published: April 2023

PDF file - 79K, Characterization of macrophages according to the M1 and M2 terminology. Monocyte-derived human macrophages were incubated in three conditions: M-CSF; LPS and condition media from MiaPaCa2 (PDA-CM). We positioned the activated macrophages in the M1/M2 spectrum (classically activated/alternatively activated), by testing the expression of CD86 and CD163, typical M1 and M2 markers, respectively. (a) Incubation with LPS resulted in pure M1 (CD86-positive) population. (b) Incubation with M-CSF produced M2 (CD163-positive) population. (c) Incubation with PDA-CM resulted in mixed M1/M2 population.
Supplementary Figure 1 from Aptamer Identification of Brain Tumor–Initiating Cells
Authors: Kim Youngmi , Wu Qiulian , Hamerlik Petra , Hitomi Masahiro , Sloan Andrew E. , Barnett Gene H. , Weil Robert J. , Leahy Patrick , Hjelmeland Anita B. , Rich Jeremy N.
Published: April 2023

PDF file - 86K, TIC- specific aptamers display specificity for TICs.
Supplementary Methods from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 85K
Supplementary Figure 6 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 128K, T-cell analyses in C57Bl/6 mice bearing B16-Ova tumors C57Bl/6 mice bearing B16-Ova tumors were injected intratumorally. Lymph nodes, spleens and tumors were collected 8 days after first virus injection, homogenized and cultured for 24 hours. Analysis of Ova-specific CD8+CD19- was performed by flow cytometry gating the CD19- population and plotting SIINFEKEL marker of Ova with CD8. Results are represented as percentage of double positive CD8 and SIINFEKEL peptide and plotted as mean +SEM. *, P<0.05.
Supplementary Figure 4 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 91K, Nude mice bearing MB49 tumors were injected with Ad5/3-CMV-mCD40L, Ad5/3-Luc1 or PBS (Mock) on days 0,2 and 4. Eight days after first virus injection mice were killed and spleens and tumors were collected, smashed and cultured for 24 hours. Homogenates were analyzed for NK+ cells (left side) and CD19+ (right side). Results are presented as mean from 6 mice + SEM. *, P<0.05, **, P<0.01.
Supplementary Table 1 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: April 2023

PDF file - 2984K, Oligonucleotide and primer sequences
Supplementary Figure 6 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: April 2023

PDF file - 3105K, TWIST1 is required for melanoma cell migration towards and invasion through collagen type I
Supplementary Table 3 from Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages
Authors: Osawa Tsuyoshi , Tsuchida Rika , Muramatsu Masashi , Shimamura Teppei , Wang Feng , Suehiro Jun-ichi , Kanki Yasuharu , Wada Youichiro , Yuasa Yasuhito , Aburatani Hiroyuki , Miyano Satoru , Minami Takashi , Kodama Tatsuhiko , Shibuya Masabumi
Published: April 2023

PDF file - 24K, List of genes upregulated in response to hypoxia and nutrient starvation double stress in human and mouse cancer cells.
Supplementary Figure 2 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: April 2023

PDF file - 3308K, High TWIST1 expression allows for melanoma spheroid outgrowth
Supplementary Figure 1 from A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
Authors: Gill Bartley J. , Gibbons Don L. , Roudsari Laila C. , Saik Jennifer E. , Rizvi Zain H. , Roybal Jonathon D. , Kurie Jonathan M. , West Jennifer L.
Published: April 2023

PDF file - 19K, echanical testing of differently stiff hydrogels with cells encapsulated at Day 1 and Day 12 (compared to acellular) shows no change in mechanical property difference with cell encapsulation
Supplementary Figures 1 - 4 from Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells
Authors: Chen Ke , Wu Kongming , Cai Shaoxin , Zhang Wei , Zhou Jie , Wang Jing , Ertel Adam , Li Zhiping , Rui Hallgeir , Quong Andrew , Lisanti Michael P. , Tozeren Aydin , Tanes Ceylan , Addya Sankar , Gormley Michael , Wang Chenguang , McMahon Steven B. , Pestell Richard G.
Published: April 2023

PDF file - 293K, Supplemental Figure 1. Reduced DACH1 mRNA in NSCLC. Supplemental Figure 2. DACH1 and p53 co-localized in a nuclear extranucleolar location.Supplemental Figure 3. Western blot analysis of H1299 cells treated with 5-Aza-2'- deoxycytidine (5MM) for 5 days and Trichostatin A (1MM, 8hrs).Supplemental Figure 4. EGFR and DACH1 expression in NSCLC vs. SCLC.
Supplementary Figure Legend from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 51K
Supplementary Figure 7 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 42K, TP53 is frequently altered in lung SqCC lines and its activation correlates with radiation resistance.
Supplementary Figure 4 from Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
Authors: Licciulli Silvia , Avila Jacqueline L. , Hanlon Linda , Troutman Scott , Cesaroni Matteo , Kota Smitha , Keith Brian , Simon M. Celeste , Puré Ellen , Radtke Fred , Capobianco Anthony J. , Kissil Joseph L.
Published: April 2023

PDF file, 267K, Effect of hypoxia on Notch1 expression and Akt activation.
Supplementary Figure 1 from Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
Authors: Licciulli Silvia , Avila Jacqueline L. , Hanlon Linda , Troutman Scott , Cesaroni Matteo , Kota Smitha , Keith Brian , Simon M. Celeste , Puré Ellen , Radtke Fred , Capobianco Anthony J. , Kissil Joseph L.
Published: April 2023

PDF file, 398K, Analysis of recombination of Notch1 alleles after Ad-Cre administration.
Supplementary Figure 2 from A Novel Model for Evaluating Therapies Targeting Human Tumor Vasculature and Human Cancer Stem–like Cells
Authors: Burgos-Ojeda Daniela , McLean Karen , Bai Shoumei , Pulaski Heather , Gong Yusong , Silva Ines , Skorecki Karl , Tzukerman Maty , Buckanovich Ronald J.
Published: April 2023

PDF File - 9042K, TVM antibodies do not cross-react with murine tumor vessels.
Supplementary Figure 1 from A Novel Model for Evaluating Therapies Targeting Human Tumor Vasculature and Human Cancer Stem–like Cells
Authors: Burgos-Ojeda Daniela , McLean Karen , Bai Shoumei , Pulaski Heather , Gong Yusong , Silva Ines , Skorecki Karl , Tzukerman Maty , Buckanovich Ronald J.
Published: April 2023

PDF File - 11199K, Co-localization of TVM expression with hCD31 expression.