bluuebunny/crossref_metadata_2025 huggingface dataset:
Isolated unilateral rupture of the alar ligament
Authors: Wong Sui-To , Ernest Kimberly , Fan Grace , Zovickian John , Pang Dachling
Published: March 2014

Only 6 cases of isolated unilateral rupture of the alar ligament have been previously reported. The authors report a new case and review the literature, morbid anatomy, and pathogenesis of this rare injury. The patient in their case, a 9-year-old girl, fell head first from a height of 5 feet off the ground. She presented with neck pain, a leftward head tilt, and severe limitation of right rotation, extension, and right lateral flexion of the neck. Plain radiographs and CT revealed no fracture but a shift of the dens toward the right lateral mass of C-1. Magnetic resonance imaging of the cervical spine showed signal hyperintensity within the left dens-atlas space on both T1- and T2-weighted sequences and interruption of the expected dark signal representing the left alar ligament, suggestive of its rupture. After 12 weeks of immobilization in a Guilford brace, MRI showed lessened dens deviation, and the patient attained full and painless neck motion.

Including the patient in this case, the 7 patients with this injury were between 5 and 21 years old, sustained the injury in traffic accidents or falls, presented with marked neck pain, and were treated with external immobilization. All patients had good clinical outcome. The mechanism of injury is hyperflexion with rotation. Isolated unilateral alar ligament rupture is a diagnosis made by excluding associated fracture, dislocation, or disruption of other major ligamentous structures in the craniovertebral junction. CT and MRI are essential in establishing the diagnosis. External immobilization is adequate treatment.
Posterior lumbar interbody fusion with stand-alone Trabecular Metal cages for repeatedly recurrent lumbar disc herniation and back pain
Authors: Lequin Michiel B. , Verbaan Dagmar , Bouma Gerrit J.
Published: March 2014

Object

Patients with recurrent sciatica due to repeated reherniation of the intervertebral disc carry a poor prognosis for recovery and create a large burden on society. There is no consensus about the best treatment for this patient group. The goal of this study was to evaluate the 12-month results of the placement of stand-alone Trabecular Metal cages in these patients.

Methods

The authors performed a retrospective analysis of 26 patients with recurrent disc herniations treated with stand-alone posterior lumbar interbody fusion (PLIF) with Trabecular Metal cages. At 1 year patients were evaluated using the Roland Morris Disability Questionnaire (RMDQ) and a visual analog scale (VAS) for back and leg pain. Furthermore, Likert scores of perceived recovery and satisfaction with the treatment were recorded. Lumbar spine radiographs after 1 year were compared with postoperative radiographs to measure subsidence. Stability of the operated segment was assessed using dynamic radiography.

Results

The patient group consisted of 26 patients (62% male) with a mean age of 45.7 ± 11.4 years (± SD). Patients had a history of 1 (31%), 2 (42%), or more (27%) discectomies at the same level. The mean follow-up period was 15.3 ± 7.3 months. At follow-up the mean VAS score for pain in the affected leg was 36.7 ± 27.9. The mean VAS score for back pain was 42.5 ± 30.2. The mean RMDQ score at follow-up was 9.8 ± 6.2. Twelve (46%) of the 26 patients had a global perceived good recovery. With respect to treatment satisfaction, 18 patients (69%) were content or very content with the operation and would recommend it. Disc height was increased immediately postoperatively, and at the 1-year follow-up it was still significantly higher compared with the preoperative height (mean 41% ± 38.7%, range −25.7 to 126.8, paired t-test, both p < 0.001), although a mean of 7.52% ± 11.6% subsidence occurred (median 2.0% [interquartile range 0.0%–10.9%], p < 0.003). No significant correlation between subsidence and postoperative back pain was found (Spearman's rho −0.2, p = 0.459). Flexion-extension radiographs showed instability in 1 patient.

Conclusions

Although only 46% of patients reported a good recovery with significant reductions in back and leg pain, 85% of patients reported at least some benefit from the operation, and a marked improvement in working status at follow-up was noted. In view of previously published poor results of instrumented lumbar fusion for patients with failed back surgery syndrome, the present data indicate that Trabecular Metal interbody fusion cages can be used in a stand-alone fashion and should not always need supplemental posterior fixation in patients with recurrent disc herniation without spinal instability, although a long-term follow-up study is warranted.
Fluorescence Indices for the Proximal Sensing of Powdery Mildew, Nitrogen Supply and Water Deficit in Sugar Beet Leaves
Authors: Leufen Georg , Noga Georg , Hunsche Mauricio
Published: March 2014

Using potted sugar beet plants we aimed to investigate the suitability of four fluorescence indices to detect and differentiate the impact of nitrogen supply, water deficit and powdery mildew in two sugar beet cultivars (Beta vulgaris L.). Plants were grown inside a polytunnel under two nitrogen levels combined with water deficit or full irrigation. Changes in plant physiology were recorded at two physiological stages with a multiparametric handheld fluorescence sensor and a fluorescence imaging system. The analysis of chlorophyll content and osmotic potential served as reference. Based on our results, the fluorescence indices “Nitrogen Balance Index” and “Simple Fluorescence Ratio” responded quite sensitively to drought stress and mildew infection. Moreover, the blue-to-far-red fluorescence ratio revealed significant stress-induced alterations in the plant physiology. In all, fluorescence indices might be used as single or combined indices for successful stress sensing. However, a robust stress differentiation by using only one fluorescence ratio could not be accomplished.
Signal Transduction of Platelet-Induced Liver Regeneration and Decrease of Liver Fibrosis
Authors: Murata Soichiro , Maruyama Takehito , Nowatari Takeshi , Takahashi Kazuhiro , Ohkohchi Nobuhiro
Published: March 2014

Platelets contain three types of granules: alpha granules, dense granules, and lysosomal granules. Each granule contains various growth factors, cytokines, and other physiological substances. Platelets trigger many kinds of biological responses, such as hemostasis, wound healing, and tissue regeneration. This review presents experimental evidence of platelets in accelerating liver regeneration and improving liver fibrosis. The regenerative effect of liver by platelets consists of three mechanisms; i.e., the direct effect on hepatocytes, the cooperative effect with liver sinusoidal endothelial cells, and the collaborative effect with Kupffer cells. Many signal transduction pathways are involved in hepatocyte proliferation. One is activation of Akt and extracellular signal-regulated kinase (ERK)1/2, which are derived from direct stimulation from growth factors in platelets. The other is signal transducer and activator of transcription-3 (STAT3) activation by interleukin (IL)-6 derived from liver sinusoidal endothelial cells and Kupffer cells, which are stimulated by contact with platelets during liver regeneration. Platelets also improve liver fibrosis in rodent models by inactivating hepatic stellate cells to decrease collagen production. The level of intracellular cyclic adenosine monophosphate (cyclic AMP) is increased by adenosine through its receptors on hepatic stellate cells, resulting in inactivation of these cells. Adenosine is produced by the degradation of adenine nucleotides such as adenosine diphosphate (ADP) and adenosine tri-phosphate (ATP), which are stored in abundance within the dense granules of platelets.
Current Strategies to Improve the Bioactivity of PEEK
Authors: Ma Rui , Tang Tingting
Published: March 2014

The synthetic thermoplastic polymer polyetheretherketone (PEEK) is becoming a popular component of clinical orthopedic and spinal applications, but its practical use suffers from several limitations. Although PEEK is biocompatible, chemically stable, radiolucent and has an elastic modulus similar to that of normal human bone, it is biologically inert, preventing good integration with adjacent bone tissues upon implantation. Recent efforts have focused on increasing the bioactivity of PEEK to improve the bone-implant interface. Two main strategies have been used to overcome the inert character of PEEK. One approach is surface modification to activate PEEK through surface treatment alone or in combination with a surface coating. Another strategy is to prepare bioactive PEEK composites by impregnating bioactive materials into PEEK substrate. Researchers believe that modified bioactive PEEK will have a wide range of orthopedic applications.
Tunneling Conductivity and Piezoresistivity of Composites Containing Randomly Dispersed Conductive Nano-Platelets
Authors: Oskouyi Amirhossein , Sundararaj Uttandaraman , Mertiny Pierre
Published: March 2014

In this study, a three-dimensional continuum percolation model was developed based on a Monte Carlo simulation approach to investigate the percolation behavior of an electrically insulating matrix reinforced with conductive nano-platelet fillers. The conductivity behavior of composites rendered conductive by randomly dispersed conductive platelets was modeled by developing a three-dimensional finite element resistor network. Parameters related to the percolation threshold and a power-low describing the conductivity behavior were determined. The piezoresistivity behavior of conductive composites was studied employing a reoriented resistor network emulating a conductive composite subjected to mechanical strain. The effects of the governing parameters, i.e., electron tunneling distance, conductive particle aspect ratio and size effects on conductivity behavior were examined.
Structural Properties of Zinc Oxide Nanorods Grown on Al-Doped Zinc Oxide Seed Layer and Their Applications in Dye-Sensitized Solar Cells
Authors: Kim Kyung , Utashiro Kazuomi , Abe Yoshio , Kawamura Midori
Published: March 2014

We fabricated zinc oxide (ZnO) nanorods (NRs) with Al-doped ZnO (AZO) seed layers and dye-sensitized solar cells (DSSCs) employed the ZnO NRs between a TiO2 photoelectrode and a fluorine-doped SnO2 (FTO) electrode. The growth rate of the NRs was strongly dependent on the seed layer conditions, i.e., thickness, Al dopant and annealing temperature. Attaining a large particle size with a high crystallinity of the seed layer was vital to the well-aligned growth of the NRs. However, the growth was less related to the substrate material (glass and FTO coated glass). With optimized ZnO NRs, the DSSCs exhibited remarkably enhanced photovoltaic performance, because of the increase of dye absorption and fast carrier transfer, which, in turn, led to improved efficiency. The cell with the ZnO NRs grown on an AZO seed layer annealed at 350 °C showed a short-circuit current density (JSC) of 12.56 mA/cm2, an open-circuit voltage (VOC) of 0.70 V, a fill factor (FF) of 0.59 and a power conversion efficiency (PCE, η) of 5.20% under air mass 1.5 global (AM 1.5G) illumination of 100 mW/cm2.
Effect of Native Oxide Film on Commercial Magnesium Alloys Substrates and Carbonate Conversion Coating Growth and Corrosion Resistance
Authors: Feliu, Jr. Sebastián , Samaniego Alejandro , Bermudez Elkin , El-Hadad Amir , Llorente Irene , Galván Juan
Published: March 2014

Possible relations between the native oxide film formed spontaneously on the AZ31 and AZ61 magnesium alloy substrates with different surface finish, the chemistry of the outer surface of the conversion coatings that grows after their subsequent immersion on saturated aqueous NaHCO3 solution treatment and the enhancement of corrosion resistance have been studied. The significant increase in the amount of aluminum and carbonate compounds on the surface of the conversion coating formed on the AZ61 substrate in polished condition seems to improve the corrosion resistance in low chloride ion concentration solutions. In contrast, the conversion coatings formed on the AZ31 substrates in polished condition has little effect on their protective properties compared to the respective as-received surface.
Assessment of the Pozzolanic Activity of a Spent Catalyst by Conductivity Measurement of Aqueous Suspensions with Calcium Hydroxide
Authors: Velázquez Sergio , Monzó José , Borrachero María , Payá Jordi
Published: March 2014

The pozzolanic activity of the spent catalyst produced by fluid catalytic cracking (FCC) has been studied by various methods in recent years. However, no quick and easy method has been reported for this activity based on the associated studies. In this work, the pozzolanic activity of a spent catalyst was investigated by measuring its electrical conductivity in aqueous suspensions of pozzolan/calcium hydroxide. The behavior of the FCC catalyst residue was compared to that of reactive and inert materials of similar chemical compositions. Further, the influence of temperature on the suspension was studied, and also, a new method was proposed in which the pozzolan/calcium hydroxide ratio was varied (with the initial presence of solid Ca(OH)2 in the system). It was concluded that the method is effective, fast and simple for evaluating the high reactivity of the catalyst. Therefore, this method is an alternative for the evaluation of the reactivity of pozzolanic materials.
Bismuth Telluride and Its Alloys as Materials for Thermoelectric Generation
Authors: Goldsmid H.
Published: March 2014

Bismuth telluride and its alloys are widely used as materials for thermoelectric refrigeration. They are also the best materials for use in thermoelectric generators when the temperature of the heat source is moderate. The dimensionless figure of merit, ZT, usually rises with temperature, as long as there is only one type of charge carrier. Eventually, though, minority carrier conduction becomes significant and ZT decreases above a certain temperature. There is also the possibility of chemical decomposition due to the vaporization of tellurium. Here we discuss the likely temperature dependence of the thermoelectric parameters and the means by which the composition may be optimized for applications above room temperature. The results of these theoretical predictions are compared with the observed properties of bismuth telluride-based thermoelements at elevated temperatures. Compositional changes are suggested for materials that are destined for generator modules.
Increased Adipogenic and Decreased Chondrogenic Differentiation of Adipose Derived Stem Cells on Nanowire Surfaces
Authors: Trujillo Nathan , Popat Ketul
Published: March 2014

Despite many advances in tissue engineering, there are still significant challenges associated with restructuring, repairing, or replacing damaged tissue in the body. Currently, a major obstacle has been trying to develop a scaffold for cartilage tissue engineering that provides the correct mechanical properties to endure the loads associated with articular joints as well as promote cell-scaffold interactions to aid in extracellular matrix deposition. In addition, adipogenic tissue engineering is widely growing due to an increased need for more innovative reconstructive therapies following adipose tissue traumas and cosmetic surgeries. Recently, lipoaspirate tissue has been identified as a viable alternative source for mesenchymal stem cells because it contains a supportive stroma that can easily be isolated. Adipose derived stem cells (ADSCs) can differentiate into a variety of mesodermal lineages including the adipogenic and chondrogenic phenotypes. Biodegradable polymeric scaffolds have been shown to be a promising alternative and stem cells have been widely used to evaluate the compatibility, viability, and bioactivity of these materials. Polycaprolactone is a bioresorbable polymer, which has been widely used for biomedical and tissue engineering applications. The fundamental concept behind successful synthetic tissue-engineered scaffolds is to promote progenitor cell migration, adhesion, proliferation, and induce differentiation, extracellular matrix synthesis, and finally integration with host tissue. In this study, we investigated the adhesion, proliferation, and chondrogenic and adipogenic differentiation of ADSCs on nanowire surfaces. A solvent-free gravimetric template technique was used to fabricate polycaprolactone nanowires surfaces. The results indicated that during the growth period i.e., initial 7 days of culture, the nanowire surfaces (NW) supported adhesion and proliferation of the cells that had elongated morphologies. However, cell on surfaces without nanowires had non-elongated morphologies. Further, immunofluorescence imaging of marker proteins showed that the nanowires surfaces did not appear to support chondrogenic differentiation whereas supported adipogenic differentiation of ADSCs.
Isothermal Time-Temperature-Precipitation Diagram for an Aluminum Alloy 6005A by In Situ DSC Experiments
Authors: Milkereit Benjamin , Giersberg Lydia , Kessler Olaf , Schick Christoph
Published: March 2014

Time-temperature-precipitation (TTP) diagrams deliver important material data, such as temperature and time ranges critical for precipitation during the quenching step of the age hardening procedure. Although the quenching step is continuous, isothermal TTP diagrams are often applied. Together with a so-called Quench Factor Analysis, they can be used to describe very different cooling paths. Typically, these diagrams are constructed based on mechanical properties or microstructures after an interrupted quenching, i.e., ex situ analyses. In recent years, an in situ calorimetric method to record continuous cooling precipitation diagrams of aluminum alloys has been developed to the application level by our group. This method has now been transferred to isothermal experiments, in which the whole heat treatment cycle was performed in a differential scanning calorimeter. The Al-Mg-Si-wrought alloy 6005A was investigated. Solution annealing at 540 °C and overcritical quenching to several temperatures between 450 °C and 250 °C were followed by isothermal soaking. Based on the heat flow curves during isothermal soaking, TTP diagrams were determined. An appropriate evaluation method has been developed. It was found that three different precipitation reactions in characteristic temperature intervals exist. Some of the low temperature reactions are not accessible in continuous cooling experiments and require isothermal studies.
The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12®
Authors: Jungersen Mikkel , Wind Anette , Johansen Eric , Christensen Jeffrey , Stuer-Lauridsen Birgitte , Eskesen Dorte
Published: March 2014

This review presents selected data on the probiotic strain Bifidobacterium animalis subsp. lactis BB-12® (BB-12®), which is the world’s most documented probiotic Bifidobacterium. It is described in more than 300 scientific publications out of which more than 130 are publications of human clinical studies. The complete genome sequence of BB-12® has been determined and published. BB-12® originates from Chr. Hansen’s collection of dairy cultures and has high stability in foods and as freeze dried powders. Strain characteristics and mechanisms of BB-12® have been established through extensive in vitro testing. BB-12® exhibits excellent gastric acid and bile tolerance; it contains bile salt hydrolase, and has strong mucus adherence properties, all valuable probiotic characteristics. Pathogen inhibition, barrier function enhancement, and immune interactions are mechanisms that all have been demonstrated for BB-12®. BB-12® has proven its beneficial health effect in numerous clinical studies within gastrointestinal health and immune function. Clinical studies have demonstrated survival of BB-12® through the gastrointestinal tract and BB-12® has been shown to support a healthy gastrointestinal microbiota. Furthermore, BB-12® has been shown to improve bowel function, to have a protective effect against diarrhea, and to reduce side effects of antibiotic treatment, such as antibiotic-associated diarrhea. In terms of immune function, clinical studies have shown that BB-12® increases the body’s resistance to common respiratory infections as well as reduces the incidence of acute respiratory tract infections.
Structures of Two New Flavonoids and Effects of Licorice Phenolics on Vancomycin-Resistant Enterococcus Species
Authors: Eerdunbayaer  , Orabi Mohamed , Aoyama Hiroe , Kuroda Teruo , Hatano Tsutomu
Published: March 2014

Since our previous study revealed that several licorice phenolics have antibacterial effects on methicillin-resistant Staphylococcus aureus (MRSA), and suppressive effects on the oxacillin resistance of MRSA, we further investigated effectiveness of licorice constituents on vancomycin-resistant Enterococcus (VRE) bacteria, and purified 32 phenolic compounds. Two flavonoids among them were characterized structurally, and identified their structures as demethylglycyrol (31) and 5,7-di-O-methylluteone (32), respectively. Examination of antibacterial effects of licorice phenolics showed that 3-arylcoumarins such as licoarylcoumarin (9) and glycycoumarin (26), and 2-arylcoumarones such as gancaonin I (17), have moderate to potent antibacterial effects on the VRE strains used in this study.
Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta
Authors: Bórquez Jorge , Ardiles Alejandro , Loyola Luis , Peña-Rodriguez Luis , Molina-Salinas Gloria , Vallejos Javier , Collado Isidro , Simirgiotis Mario
Published: March 2014

The new mulinane diterpenoids 1 and 2 were isolated from the EtOAc extract of Mulinum crassifolium, while the rearranged mulinane 5, which was isolated for the first time from a natural source, was isolated from Azorella compacta. Compounds 1–2 were prepared by semi-synthesis thorough acetylation of the diterpene 17-acetoxymulinic acid (3). A mechanism of reaction was proposed, while the structures of the new compounds were elucidated on the basis of comprehensive spectroscopic analysis and computational methods.
Electrochemical Synthesis of Mesoporous CoPt Nanowires for Methanol Oxidation
Authors: Serrà Albert , Montiel Manuel , Gómez Elvira , Vallés Elisa
Published: March 2014

A new electrochemical method to synthesize mesoporous nanowires of alloys has been developed. Electrochemical deposition in ionic liquid-in-water (IL/W) microemulsion has been successful to grow mesoporous CoPt nanowires in the interior of polycarbonate membranes. The viscosity of the medium was high, but it did not avoid the entrance of the microemulsion in the interior of the membrane’s channels. The structure of the IL/W microemulsions, with droplets of ionic liquid (4 nm average diameter) dispersed in CoPt aqueous solution, defined the structure of the nanowires, with pores of a few nanometers, because CoPt alloy deposited only from the aqueous component of the microemulsion. The electrodeposition in IL/W microemulsion allows obtaining mesoporous structures in which the small pores must correspond to the size of the droplets of the electrolytic aqueous component of the microemulsion. The IL main phase is like a template for the confined electrodeposition. The comparison of the electrocatalytic behaviours towards methanol oxidation of mesoporous and compact CoPt nanowires of the same composition, demonstrated the porosity of the material. For the same material mass, the CoPt mesoporous nanowires present a surface area 16 times greater than compact ones, and comparable to that observed for commercial carbon-supported platinum nanoparticles.
Assessment and Correction of on-Orbit Radiometric Calibration for FY-3 VIRR Thermal Infrared Channels
Authors: Xu Na , Chen Lin , Hu Xiuqing , Zhang Liyang , Zhang Peng
Published: March 2014

FengYun-3 (FY-3) Visible Infrared Radiometer (VIRR), along with its predecessor, Multispectral Visible Infrared Scanning Radiometer (MVISR), onboard FY-1C&D have had continuous global observation more than 14 years. This data record is valuable for weather prediction, climate monitoring, and environment research. Data quality is vital for satellite data assimilations in Numerical Weather Prediction (NWP) and quantitative remote sensing applications. In this paper, the accuracies of radiometric calibration for VIRR onboard FY-3A and FY-3B, in thermal infrared (TIR) channels, are evaluated using the Low Earth Orbit (LEO)-LEO simultaneous nadir overpass intercalibration method. Hyperspectral and high-quality observations from Infrared Atmosphere Sounding Instrument (IASI) onboard METOP-A are used as reference. The biases of VIRR measurements with respect to IASI over one-and-a-half years indicate that the TIR calibration accuracy of FY-3B VIRR is better than that of FY-3A VIRR. The brightness temperature (BT) measured by FY-3A/VIRR is cooler than that measured by IASI with monthly mean biases ranging from −2 K to −1 K for channel 4 and −1 K to 0.2 K for channel 5. Measurements from FY-3B/VIRR are more consistent with that from IASI, and the annual mean biases are 0.84 ± 0.16 K and −0.66 ± 0.18 K for channels 4 and 5, respectively. The BT biases of FY-3A/VIRR show scene temperature-dependence and seasonal variation, which are not found from FY-3B/VIRR BT biases. The temperature-dependent biases are shown to be attributed to the nonlinearity of detectors. New nonlinear correction coefficients of FY-3A/VIRR TIR channels are reevaluated using various collocation samples. Verification results indicate that the use of the new nonlinear correction can greatly correct the scene temperature-dependent and systematic biases.
Morphological characterization of fullerene–androsterone conjugates
Authors: Ruiz Alberto , Suárez Margarita , Martin Nazario , Albericio Fernando , Rodríguez Hortensia
Published: March 2014

Here we report on the self-organization characteristics in water of two diastereomer pairs of fullerene–androsterone hybrids that have the hydrophobic C60 appendage in the A and D ring of the androsterone moiety, respectively. The morphology and particle size in aqueous solution were determined by transmission electron microscopy (TEM) and dynamic light scattering (DLS), with satisfactory agreement between both techniques. In general, these fullerene derivatives are shown to organize into spherical nano-scale structures with diameters in the ranges of 10–20 and 30–50 nm, respectively.
APPLICATION OF TERRESTRIAL PHOTOGRAMMETRY TO THE CREATION OF A 3D MODEL OF THE SAINT HEDWIG CHAPEL IN THE KAŇOVICE
Authors: Mikoláš Milan , Jadviščok Petr , Molčák Vlastimil
Published: March 2014

The present article focuses on application of terrestrial photogrammetry for the purposes of creation of photogrammetric documentation of building structures with the use of digital camera – a widely accessible device. First, the article briefly describes the individual intermediate operations of the whole process leading to the creation of a three-dimensional structure. Next, attention is given to operations related to camera calibration, reconnaissance of the locality of interest, photographing itself, creation of the 3D model as well as to presentation of graphical output. In conclusion, the article focuses on determining the accuracy of photogrammetric measuring.
ANTI-SPACE: THE POLITICAL COMPLEXION OF AN INNER CITY ART GALLERY
Authors: Vickery Jonathan P.
Published: March 2014

The subject of this paper is an inner city artist-run gallery called Eastside Projects. As part of an historical trend in artistrun spaces, Eastside Projects have innovated a strategic approach to post-industrial space, their location and role within the city of Birmingham, UK. This paper outlines their approach in the context of the recent cultural policy frameworks impressed on publicly funded city-based art organisations. It attempts to extend the conceptualisation of contemporary art in the city within urban studies generally, specifically investigating the theoretical potential of Eastside Project’s curatorial strategy. How can we define public agency for art in the neoliberal city? For Eastside Projects, agency is defined principally through space and the aesthetics of space. This paper proposes a theoretical framework for articulating the political aesthetics of new public spaces for art.
L'ayatollah Mesbah Yazdi et le Front de la persistance, ou le radicalisme en République islamique
Authors: Fourquet Thomas
Published: March 2014

L’élection de Hassan Rohani et les premiers mois de saprésidence ont été marqué par un consensus relatif qui tranche avec les deux mandats précédents, marqués par des scissions successives. Est-ce le nouveau cours de la politique iranienne, voire une évolution du régime vers une plus grande modération ? Quoi qu’il en soit, la tendance radicale regroupée autour de l’ayatollah Mohammad-Taqi Mesbah Yazdi se trouve marginalisée après l’échec de son candidat, Said Jalili. Il nous a cependant paru utile de revenir sur l’histoire d’un courant dont l’intransigeance, voire la violence, rappellent les premières années de la Révolution. Philosophe ayant fait une entrée fracassante en politique à la fin des années 90, directeur d’un institut d’enseignement très richement doté, l’institut Emam Khomeini, et d’un séminaire qui a formé de nombreux cadres des services de renseignement, Mesbah reste néanmoins une figure isolée, qui suscite la méfiance jusque dans son propre camp. La raison en est qu’en défendant une version radicalement anti-démocratique de la velayate faqih, il met la République islamique face à ses propres contradictions.
Strategies for the evaluation and selection of potential vaginal probiotics from human sources: an exemplary study
Authors: Domig K.J. , Kiss H. , Petricevic L. , Viernstein H. , Unger F. , Kneifel W.
Published: March 2014

During the last years, the application of probiotics in gynaecological clinical practice has gained increasing relevance regarding therapy and prevention. This trend has also provoked the need for having tailored pharmaceutical preparations containing powerful microbial strains with defined properties. For the development of such preparations, several factors and criteria have to be considered, thereby not only focusing on identity and safety aspects as well as individual properties of the bacterial strains, but also on technological issues, such as stability and targeted release from the preparation. Against this background, this report exemplarily addresses the development procedure of a probiotic bacterial formulation for gynaecological application, covering the search for suitable strains, assessing their microbiological, molecular biological and physiological characterisation, and the selection for their use in clinical trials. In detail, starting with 127 presumptive lactobacilli isolates of vaginal origin, a step-by-step selection of candidate strains meeting special criteria was thoroughly examined, finally leading to a preparation consisting of four individual Lactobacillus strains that possess particular significance in women's urogenital health. Relevant issues and quality criteria of probiotic preparations used in gynecology are addressed and exemplarily introduced.
Gut carbohydrate metabolism instead of fat metabolism regulated by gut microbes mediates high-fat diet-induced obesity
Authors: Li M. , Gu D. , Xu N. , Lei F. , Du L. , Zhang Y. , Xie W.
Published: March 2014

The aim of this study was to investigate the mechanisms underlying the involvement of gut microbes in body weight gain of high-fat diet-fed obesity-prone (obese) and obesity-resistant (lean) mice. C57BL/6 mice were grouped into an obese group, a lean group and a normal control group. Both obese and lean mice were fed a high-fat diet while normal control mice were fed a normal diet; they were observed for six weeks. The results showed that lean mice had lower serum lipid levels, body fat and weight gain than obese mice. The ATPase, succinate dehydrogenase and malate dehydrogenase activities in liver as well as oxygen expenditure and rectal temperature of lean mice were significantly lower than in obese mice. As compared with obese mice, the absorption of intestinal carbohydrates but not of fats or proteins was significantly attenuated in lean mice. Furthermore, 16S rRNA abundances of faecal Firmicutes and Bacteroidetes were significantly reduced in lean mice. In addition, faecal β-D-galactosidase activity and short chain fatty acid levels were significantly decreased in lean mice. Expressions of peroxisome proliferator-activated receptor gamma 2 and CCAAT/enhancer binding protein-β in visceral adipose tissues were significantly downregulated in lean mice as compared with obese mice. Resistance to dyslipidaemia and high-fat diet-induced obesity was mediated by ineffective absorption of intestinal carbohydrates but not of fats or proteins, probably through reducing gut Bacteroidetes and Firmicutes contents and lowering of gut carbohydrate metabolism. The regulation of intestinal carbohydrates instead of fat absorption by gut microbes might be a potential treatment strategy for high-fat diet-induced obesity.
Degradation of zearalenone in swine feed and feed ingredients by Bacillus subtilis ANSB01G
Authors: Lei Y.P. , Zhao L.H. , Ma Q.G. , Zhang J.Y. , Zhou T. , Gao C.Q. , Ji C.
Published: March 2014

Zearalenone (ZEA) and its derivatives are mycotoxins that can cause oestrogenic effects and impair the reproductive physiology of animals, especially in female swine. Strategies to reduce or eliminate ZEA contamination in foods and feeds are very much needed. Among 36 bacterial isolates obtained from a variety of animal intestinal chyme, mouldy foods and feeds, soils, etc., five isolates demonstrated the ability to reduce more than 50% of ZEA in a liquid medium; ANSB01G isolate taken from normal broiler intestinal chyme reduced ZEA the most, by 88.65%. Using physiological, biochemical, and 16S rRNA gene sequence analysis methods, the ANSB01G isolate was identified as Bacillus subtilis. Under simulated intestinal tract conditions, the ANSB01G B. subtilis isolate degraded 84.58, 66.34 and 83.04% of ZEA in naturally contaminated maize, dried distillers’ grains with solubles, and swine complete feed, respectively. The highest degradation of ZEA occurred when the mycotoxin was co-incubated with the whole bacterial culture, resulting in a reduction of 88.65%, followed by 75.60% using culture supernatant, 26.11% using cell extracts, and 15.06% using viable cells. Treatments consisting of both heating and addition of proteinase K significantly reduced the rate of ZEA degradation in the culture supernatant, indicating that the ZEA degradation might be enzymatic. B. subtilis ANSB01G displayed resistance to simulated gastrointestinal tract environments and antimicrobial activities against several common bacterial pathogens, including Escherichia coli, Salmonella typhimurium and Staphylococcus aureus. These properties of B. subtilis ANSB01G suggest the possibility of its potential to effectively degrade ZEA in feed and to develop functional feed products for livestock industries.
Penile fracture: Penoscrotal approach with degloving of penis after Magnetic Resonance Imaging (MRI)
Authors: Antonini Gabriele , Vicini Patrizio , Sansalone Salvatore , Garaffa Giulio , Vitarelli Antonio , De Berardinis Ettore , Von Heland Magnus , Giovannone Riccardo , Casciani Emanuele , Gentile Vincenzo
Published: March 2014

Fracture of the penis, a relatively uncommon emergency in Urology, consists in the traumatic rupture of the tunica albuginea of the corpus cavernosum. Examination and clinical history can be highly suspicious of penile fracture in the majority of cases and ultrasonography (USS) can be useful to identify the exact location of the tunical rupture, which is proximal in 2/3 of cases and therefore manageable through a penoscrotal approach. Although expensive and not readily available in the acute setting, Magnetic Resonance Imaging (MRI) may play a role in the differential diagnosis with rupture of a circumflex or dorsal vein of the penis or when the tunical rupture is not associated with tear of the overlying Buck’s fascia. This form of imaging is more sensitive than USS at identifying the presence of a tunical tear. The treatment of choice is immediate surgical repair, which allows preserving erectile function and minimizing corporeal fibrosis.
Penile strangulation: An unusual sexual practice that often presents an urological emergency
Authors: Dell’Atti Lucio
Published: March 2014

Placement of constricting devices around the penis for autoerotic purposes or increasing of sexual performance represents a well-known challenge for urologists. Penile incarceration is a urologic emergency with potentially severe clinical consequences. In many cases a rapid intervention and a sudden removal of the foreign body it is enough so that patients need no further intervention. We report three different cases of strangulating objects (metallic ring, metal bearing and plumbing pipe) presented at our emergency department and three different methods of devices extraction practiced. Remove these devices can be challenging and often requires resourcefulness and multidisciplinary approach.
Rare case of intra-testicular adenomatoid tumour
Authors: Migliorini Filippo , Baldassarre Roberto , Artibani Walter , Martignoni Guido , Brunelli Matteo
Published: March 2014

Adenomatoid tumors are rare benign neoplasms considered of mesothelial origin. They are usually asymptomatic and slow growing masses. They account for 30% of paratesticular tumors and very rarely involve the testicular parenchyma. Only ten such cases have been reported in the literature so far. Ideal treatment should be excision of the tumor avoiding orchidectomy. Nevertheless, because of the rarity of the lesion and the difficulty of distinguishing it from malignancy, radical orchidectomy is often performed. We describe a case of a 31 years old caucasian man who presented with a moderately symptomatic left testicular mass, normal tumor markers and normal sex hormones levels. The ultrasound showed an hypoechoic intratesticular nodule of 0.8 cm in diameter. The patient underwent intraoperative frozen section of the nodule which could not exclude malignancy with certainty. A radical orchiectomy was therefore performed. Subsequent definitive histological and molecular report described an adenomatoid tumor involving the parenchyma of the testis.
The 2011 Nabro eruption, a SO2 plume height analysis using IASI measurements
Authors: Clarisse L. , Coheur P.-F. , Theys N. , Hurtmans D. , Clerbaux C.
Published: March 2014

Abstract. In the wake of the June 2011 Nabro eruption, large stratospheric plumes were observed by several instruments up to altitudes of 21 km, much higher than initial reported injection heights. It has been debated whether deep convection associated with the Asian Summer Monsoon anticyclone played a vital role in the vertical transport of the plume. Here we present a new and fast SO2 height retrieval algorithm for observations of the Infrared Atmospheric Sounding Interferometer (IASI). A comprehensive validation with forward trajectories and coincident CALIOP measurements is presented which indicates an accuracy better than 2 km for plumes below 20 km and SO2 columns up to the 1 DU level. We use this new product to analyse the Nabro eruption. Our findings indicate an initial plume located mainly between 15 and 17 km for which the lower parts underwent in succession rapid descent and uplift, within the Asian Monsoon anticyclone circulation, up to the stable thermal tropopause between 16 and 18 km, from where it slowly ascended further into the stratosphere. Evidence is presented that emissions in the first week of the eruption also contributed to the stratospheric sulfur input. This includes a second eruption between 15 and 17 km on the 16th and continuous emissions in the mid-troposphere of which some were also entrained and lifted within the anticyclonic circulation.
Tropical deep convection and density current signature in surface pressure: comparison between WRF model simulations and infrasound measurements
Authors: Costantino L. , Heinrich P.
Published: March 2014

Abstract. Deep convection is a major atmospheric transport process in the tropics, affecting the global weather and the climate system. In the framework of the ARISE (Atmospheric dynamics Research InfraStructure in Europe) project, we combine model simulations of tropical deep convection with in situ ground measurements from an IMS (International Monitoring System) infrasound station in the Ivory Coast to analyze the effects of density current propagation. The WRF (Weather Research and Forecasting) model is firstly run in a simplified (referred to as "idealized case") and highly resolved configuration to explicitly account for convective dynamics. Then, a coarser three-dimensional simulation (referred to as "real") is nudged towards meteorological reanalysis data in order to compare the real case with the idealized model and in situ observations. In the 2-D run, the evolution of a deep convective cloud generates a density current that moves outward up to 30 km away from storm center. The increase in surface density (up to 18 g m−3 larger than surrounding air) is mostly due to the sudden temperature decrease (down to −2 °C, with respect to the domain-averaged value) from diabatic cooling by rain evaporation near ground level. It is accompanied by a dramatic decrease in relative humidity (down to −50%), buoyancy (down to −0.08 m s−2), equivalent potential temperature (25 °C lower than the planetary boundary layer (PBL)) and the rapid enhancement of horizontal wind speed (up to 15 m s−2). If temperature and density changes are strong enough, surface pressure becomes largely affected and high-frequency disturbances (up to several tens of Pa) can be detected at the leading edges of density current. The moister and warmer air of subcloud layer is lifted up and replaced by a more stable flow. The resulting thermodynamical instabilities are shown to play a key role in triggering new convection. If the initial environment is sufficiently unstable, they can give rise to continuous updrafts that may lead to the transition from single-cell to multicell cloud systems, even without the presence of an initial wind shear. The overall consistence and similarity between idealized and real simulation, and the good agreement of the real case with in situ retrievals of temperature, pressure, wind speed and direction, seem to confirm the ability of 2-D and 3-D models to well reproduce convective dynamics. Surface pressure disturbances, simulated in both the idealized and real cases as a consequence of cold pool propagation, are very similar to those recorded in the Ivory Coast. Present results stress the direct link between mesoscale convective system activity and high-frequency surface pressure variations, suggesting the possibility of developing a new method for real-time rainstorm tracking based on the ground-based infrasound monitoring of pressure field.
Probabilistic approach to cloud and snow detection on Advanced Very High Resolution Radiometer (AVHRR) imagery
Authors: Musial J. P. , Hüsler F. , Sütterlin M. , Neuhaus C. , Wunderle S.
Published: March 2014

Abstract. Derivation of probability estimates complementary to geophysical data sets has gained special attention over the last years. Information about a confidence level of provided physical quantities is required to construct an error budget of higher-level products and to correctly interpret final results of a particular analysis. Regarding the generation of products based on satellite data a common input consists of a cloud mask which allows discrimination between surface and cloud signals. Further the surface information is divided between snow and snow-free components. At any step of this discrimination process a misclassification in a cloud/snow mask propagates to higher-level products and may alter their usability. Within this scope a novel probabilistic cloud mask (PCM) algorithm suited for the 1 km × 1 km Advanced Very High Resolution Radiometer (AVHRR) data is proposed which provides three types of probability estimates between: cloudy/clear-sky, cloudy/snow and clear-sky/snow conditions. As opposed to the majority of available techniques which are usually based on the decision-tree approach in the PCM algorithm all spectral, angular and ancillary information is used in a single step to retrieve probability estimates from the precomputed look-up tables (LUTs). Moreover, the issue of derivation of a single threshold value for a spectral test was overcome by the concept of multidimensional information space which is divided into small bins by an extensive set of intervals. The discrimination between snow and ice clouds and detection of broken, thin clouds was enhanced by means of the invariant coordinate system (ICS) transformation. The study area covers a wide range of environmental conditions spanning from Iceland through central Europe to northern parts of Africa which exhibit diverse difficulties for cloud/snow masking algorithms. The retrieved PCM cloud classification was compared to the Polar Platform System (PPS) version 2012 and Moderate Resolution Imaging Spectroradiometer (MODIS) collection 6 cloud masks, SYNOP (surface synoptic observations) weather reports, Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) vertical feature mask version 3 and to MODIS collection 5 snow mask. The outcomes of conducted analyses proved fine detection skills of the PCM method with results comparable to or better than the reference PPS algorithm.
The role of phosphorus dynamics in tropical forests – a modeling study using CLM-CNP
Authors: Yang X. , Thornton P. E. , Ricciuto D. M. , Post W. M.
Published: March 2014

Abstract. Tropical forests play a significant role in the global carbon cycle and global climate. However, tropical carbon cycling and the feedbacks from tropical ecosystems to the climate system remain critical uncertainties in the current generation of carbon–climate models. One of the major uncertainties comes from the lack of representation of phosphorus (P), currently believed to be the most limiting nutrient in tropical regions. Here we introduce P dynamics and C–N–P interactions into the CLM4-CN (Community Land Model version 4 with prognostic Carbon and Nitrogen) model and investigate the role of P cycling in controlling the productivity of tropical ecosystems. The newly developed CLM-CNP model includes all major biological and geochemical processes controlling P availability in soils and the interactions between C, N, and P cycles. Model simulations at sites along a Hawaiian soil chronosequence indicate that the introduction of P limitation greatly improved the model performance at the P-limited site. The model is also able to capture the shift in nutrient limitation along this chronosequence (from N limited to P limited), as shown in the comparison of model-simulated plant responses to fertilization with the observed data. Model simulations at Amazonian forest sites show that CLM-CNP is capable of capturing the overall trend in NPP (net primary production) along the P availability gradient. This comparison also suggests a significant interaction between nutrient limitation and land use history. Model experiments under elevated atmospheric CO2 ([CO2]) conditions suggest that tropical forest responses to increasing [CO2] will interact strongly with changes in the P cycle. We highlight the importance of two feedback pathways (biochemical mineralization and desorption of secondary mineral P) that can significantly affect P availability and determine the extent of P limitation in tropical forests under elevated [CO2]. Field experiments with elevated CO2 are therefore needed to help quantify these important feedbacks. CO2 doubling model experiments show that tropical forest response to elevated [CO2] can only be predicted if the interactions between C cycle and nutrient dynamics are well understood and represented in models. Predictive modeling of C–nutrient interactions will have important implications for the prediction of future carbon uptake and storage in tropical ecosystems and global climate change.