bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Staffing Strategy on Competitive Advantage: in Jordanian Pharmaceutical Industry Companies
Authors: Alrawashdeh Sabah Adel , Allafi Khaled Khalf
Published: December 2022

This study aimed to identify the impact of the staffing strategy on competitive advantage in Jordanian pharmaceutical companies. The study population was represented by the managers of senior management in companies working in the Jordanian pharmaceutical industry counted (21) companies. A proportional stratified sample was drawn for the purposes of representing the study population. The study sample was (178) and the study relied on the descriptive analytical approach. To achieve its objectives, a questionnaire was used to collect data. The study used statistical program (SPSS) to analyze the data. The results showed that there is an impact from human resource staffing on the competitive advantage in Jordanian pharmaceutical companies. The researchers recommended the need to enhance and benefit from the components of human resource staffing strategies to study the organizational environment in Jordanian pharmaceutical companies to achieve competitive advantage.
Pengendalian Internal pada Pondok Pesantren Al I’tishom Kubu Raya
Authors: Ruci Dewa , Lestary Dini
Published: December 2022

Islamic boarding school is a non-profit organization. Internal control over financial reporting in religious entities, especially Islamic boarding schools, is rarely a special concern in practice and scientific studies. In making financial reports, trust is needed to separate organizational interests and personal interests, this is to avoid conflicts of personal interest in taking advantage of the organization. The researcher wants to dig deeper into the concept of amanah, and Islamic boarding school administrators account for Islamic boarding schools' finances, not only to the people but also to know the understanding of accountability to Allah as God. Islamic boarding schools on financial management. This research method is qualitative followed by an interpretive paradigm that provides guidelines for choosing the right research methodology, namely case studies. the method of collecting and analyzing the research data is by observation, interviews, and document analysis. The results of this study are that the Al I'tishom Kubu Raya Islamic Boarding School is in accordance with the internal control structure which consists of 5 (five) components namely Control Environment, Risk Assessment, Control Activities, Information and Communication, and Supervision, at this time it has been fulfilled even though it is not overall. Likewise, the financial reports of the Al I'tishom Kubu Raya Islamic Boarding School at this time do not compile financial reports independently, but are only tasked with reporting all forms of transactions that occur at the Islamic boarding school to the financial sector. Islamic boarding school financial records are made by the assistant treasurer by keeping simple bookkeeping accompanied by proof of transactions. The existence of valid evidence and records is also a manifestation of the mandate and internal control that is applied to the Al I'tishom Kubu Raya Islamic Boarding School.
DETERMINATION OF ANTHOCYANIN LEVEL IN KIDNEY BEAN (Phaseolus vulgaris L.) TEMPEH AS A HEPATOPROTECTIVE AGENT
Authors: Anggraini Devina Ingrid , Mirantana Listiya Pramesti
Published: December 2022

Liver is a part of body that is used as a toxin neutralizer as well as a target for increasing free radicals. In counteracting free radicals, body needs antioxidants in one of the plant secondary metabolites, namely anthocyanins. Anthocyanins are organic compounds from the water-soluble flavonoid family that give red, blue, and violet colors. Fermentation can increase anthocyanin levels in kidney beans. This study aimed to determine the presence of anthocyanins in kidney bean (Phaseolus vulgaris L.) tempeh which can be used as a hepatoprotective agent and to determine the anthocyanin levels in kidney bean (Phaseolus vulgaris L.) tempeh. Qualitative analysis using HCl and NaOH with positive results showed the color change to solid red then to bluish green and then faded. Determination of total anthocyanin levels was carried out using UV-Vis spectrophotometric method with the pH differential principal in anthocyanin showed in mg/100gram sample at a maximum wavelength of 525.5 nm. The result was that the average anthocyanin content was 40.37mg/100gram with a variant coefficient is 0.325%.
Phenomena in Romance verb paradigms: Syncretism, order of inflectional morphemes and thematic vowel
Authors: Baldi Benedetta , Savoia Leonardo M.
Published: December 2022

This article aims to propose a treatment of the internal morphological organization of words, based on the idea that morphology is part of syntactic computation. We disagree with Distributed Morphology model, whereby morphology is identified with a post-syntactic component conveying an information ‘separated from the original locus of that information in the phrase marker’ (Embick and Noyer 2001: 557) by rules manipulating syntactic nodes. We also consider inadequate the costly and complex syntactic structures that cartographic approach maps into inflectional strings. We pursue a different conceptualization assuming that morphology is governed by the same rules and principles of syntax. Sub-word elements, including inflections, thematic exponents and clitics, are fully interpretable and enter (pair-)merge operations (in the sense of Chomsky 2020a,b, 2021) according to their content, giving rise to complex words.
Frames and political choice in Scottish election campaigns
Authors: Jakusné Harnos Éva , Gergi-Horgos Mátyás
Published: December 2022

The paper presents interdisciplinary research using the framework of cognitive linguistics based metaphor theory and nationalism studies of political science. Frames of movement are placed under scrutiny during the discourse analysis of the 2016 and 2021 election manifestos of the Scottish National Party and social media posts. In relation to metaphors of movement, images describing the future of an independent Scotland are also detected. The authors attempt to analyse and interpret findings both from the perspective of cognitive linguistics and ethno-symbolism. Apart from the texts of the manifestos, the timeframe of the research involved social media posts two months preceding and two months following the elections in both cases. Methodology was issue-driven and computer assisted but supervised: key words linked to movement were extracted from the manifestos and clustered. Their occurrence and frequency in the social media posts was checked. In the qualitative analysis phase, messages of the manifestos and of the posts were contrasted in order to answer our research question what kind of persuasive political discourse was used when options for the citizens were outlined.
Ground Zero: A bibliometric analysis of L2 vocabulary research 1986-1990
Authors: Meara Paul
Published: December 2022

This paper uses a co-citation analysis to examine the research on vocabulary acquisition that was published in 1990. Two analyses are presented. The first is a detailed account of the 1990 research on its own terms. The second analysis places this work in a larger context by looking at research published in a five-year window covering 1986-1990.
E-Training Penyusunan Karya Tulis Ilmiah Best Practice Bagi Guru dan Kepala Sekolah untuk Meningkatkan Profesionalitas
Authors: Tri Satyawati Sophia , Dwikurnaningsih Yari , Ismanto Bambang , Iriani Ade , Wasitohadi Wasitohadi , Waruwu Marinu
Published: December 2022

Principals and teachers play a strategic role in improving the quality of education as shown by the best experience (Best Practice) in carrying out their main tasks and functions. Best practices need to be disseminated and published in order to be a reflection and inspiration for others to improve the quality of education. However, the facts show that principals and teachers do not yet have adequate knowledge and skills in compiling best practice scientific papers. This community service activity aims to improve skills in compiling best practice scientific papers for teachers and principals at  Private Education Foundations. The training is carried out online with the following methods: lecture, question and answer, discussion, guidance, and performance. The success of community service is shown by: 1) the number of participants exceeding the target of 50 increases to 53 people; 2) attendance reached 92.96% (very good); 3) The increase in the pre test - post test scores reached 76% (Good); 4) The number of training products reached 71.69% (Good) with a product quality score of 77.80 (Good). This success shows the enthusiasm of the participants and very high awareness of the importance of writing best practices for increasing the professionalism of teachers and principals.
AN EFFECTIVE AND EFFICIENT FEATURES VECTORS FOR RANSOMWARE DETECTION VIA MACHINE LEARNING TECHNIQUE
Authors: A. Khalil Nawaf , M. Khammas Ban
Published: December 2022

Ransomware is a high major danger program that may harm any company or person and cost them hundreds of billions. Its number growing rapidly across the years.  As a result, creating a strong defense strategy against this crucial virus is required. Ransomware has grown in importance, and its consequences are becoming more severe. To solve the problem of effectively detecting ransomware, so this paper introduces a new technique to detect ransomware based on five machine learning techniques. To evaluate the proposed method, different evaluation metrics have been used.  The approach was captured n-gram characteristics based on static analysis and used n-gram vector with CF-NCF values to build the models. Using real datasets, the proposed approach shows Its ability to reliably identify between goodware and ransomware files successfully with an accuracy of classification of equal to 98.33%.
DİJİTAL EFEKTLER ÇAĞINDA GÖRSEL DEVAMLILIĞI SAĞLAMAK: BLADE RUNNER ve BLADE RUNNER 2049 ÜZERİNE
Authors: SEÇMEN Emre Ahmet
Published: December 2022

Günümüzde dijital üretim sistemi film yapımcılığının temel yöntemini oluşturmaktadır. Kurgu aşamasının bilgisayar ortamına geçişi ile başlayan dijitale geçiş süreci, pelikülün terk edilmesi ve gösterimin dijitalleşmesi ile tamamlanmıştır. Görsel efekt kategorisi de dijital üretim sürecinde kurgu sonrası bilgisayar ortamına taşınan ve sonrasında orada kalıcı hale gelen üretim başlıklarından biri haline gelmiştir. Bilgisayar desteği veya tamamen bilgisayar yaratımı olmaksızın bir efekt üretimi artık söz konusu değildir. Bu dönüşüm dijital öncesi dönemde daha çok yapım öncesi ve yapım sürecinde gerçekleştirilen efekt üretimini, tamamen yapım sonrası aşamasına kaydırmıştır. Bilgisayar tabanlı üretime geçilmeye başlanan 70’li yılların sonlarında
görsel efekt üretimi açısından üretimi zor olan bilimkurgu, fantastik ve distopya temalarına sahip projeler, gelişen üretim teknolojisi ile birlikte üretimi mümkün hale gelmiş ve günümüzde kült niteliğine erişmiştir.

2000’li yıllardan itibaren tamamen dijital üretime yönlenen sinema endüstrisinde, dijital dönem öncesi üretimi yapılan bir film veya film serisinin günümüzde devam ettirilmesi sık karşımıza çıkan bir tercihtir. Bu türde üretimlerde hem filmi üreten hem de filmi izleyenler için önemli olan noktalardan biri de görsel devamlılık olacaktır. Görsel devamlılıkta efektlerin üretimi son derece hassasiyet gerektirmekle birlikte, teorikte ve pratikteki temel tartışma da bilgisayarlarda üretilen dijital efektler ile dijital dönem öncesi yapılan özel efektlerin gerçekliğe yakınlığı, yapaylığı ve görsel devamlılığı eksenlerinde sürmektedir. Bu araştırmada yapım tasarımında özel efekt kullanımı ile öne çıkan 1982 yapımı Blade Runner ile bu hikâyenin 30 yıl sonrasını anlatan 2017 yapımı Blade Runner 2049 (Bıçak Sırtı 2049) filmleri arasındaki görsel devamlılığın sağlanmasında dijital efektlerin rolünün tartışılması amaçlanmaktadır. Keşif amaçlı bir alan araştırması olan bu çalışmada filmler arası betimsel analiz yöntemi kullanılmış, filmlerin yapım sürecinde görev alan ekip üyelerinin kamera arkası röportajlarından ayrıca yararlanılmıştır. Araştırmada farklı üretim dönemlerinde gerçekleştirilen görsel efektlerin her iki filmde de yapaylığa düşmeden ve birbirleri arasında bir uyum yakalama konusunda hassasiyet gösteren bir sistemle üretildiği, görsel devamlılığa uyum sağladığı sonucuna varılmaktadır.
Germany’s Cybersecurity Policy
Authors: Brzostek Agnieszka
Published: December 2022

The German Federal Republic is one of the states whose state policy in the field of cybersecurity is considered to be coherent and effective. However, even Germany is a country exposed to numerous attacks. Ubiquitous technology in every aspect of our lives, and in addition the COVID-19 pandemic, introducing widespread mobile work and online education, have created even greater threats. By adapting internal legislation, indicating strategic and specific goals, Germany is part of the EU cybersecurity policy in its cybersecurity strategies. Prior to the adoption of the NIS 2 directive, Germany had already created a legal basis that would effectively and efficiently protect German cyberspace. In order to strengthen the effectiveness of their cybersecurity policy, Germany is strengthening cooperation between federal authorities, business, science and strengthening digital sovereignty.
Concordia or Consent. Catholics Utrisque Ritus of the Lviv Ecclesiastical Province in the Orbit of Canon Law and Customary Regulations
Authors: Osadczy Włodzimierz
Published: December 2022

In the area of the Lviv church province the coexistence of Christians of the Greek and Latin traditions had developed for centuries. After the introduction of the church union in the dioceses of Lviv and Przemyśl at the beginning of the 18th century, the entire Christian population found itself within the Catholic Church. Despite the doctrinal community, Catholics of various rites were subject to different religious customs and functioned according to different calendars. During the widespread nationalisation of the local people on the basis of religious traditions, various national identities emerged, becoming more and more radical and hostile to each other. Hence, on the ecclesiastical level, initiatives appeared to alleviate tensions and introduce order and harmony resulting from Christian teaching. Concordia of 1863 was such an attempt at an agreement, which under the canon law consolidated the established customs that had been present in the religious life of Galicia for centuries.
Selected Medical and Legal Problems of a Surgeon’s Assistant as a New Speciality in the Polish Healthcare System
Authors: Sitarz Robert , Poździk Rafał
Published: December 2022

On 26 November 2021, a new speciality concerning surgical physician assistance (Polish: chirurgiczna asysta lekarza) was introduced in a regulation of the Polish Minister of Health. The term ‘surgeon’s assistant’ refers to an independent healthcare professional authorised to perform certain medical and surgical procedures under the supervision of a specialist surgeon. Undoubtedly, the successful introduction of this new speciality depends primarily on the appropriate training process. Then, it will be necessary to change the internal procedures existing at medical facilities, to ensure that the work of surgeon’s assistants is organised properly and enables their effective cooperation with other qualified practitioners. The introduction of a new speciality is a great challenge for hospitals, surgeons and society in general. It requires taking many additional legal and organisational measures by hospitals as well as at the national level.
Detailed Characteristics of the Limitation of the Right of Access to Public Information Due to Regulations on the Recapitalization of Certain Institutions and Governmental Financial Stabilization Instruments
Authors: Tomaszewska Katarzyna
Published: December 2022

As a public subjective right, the general right to public information is subject to limitations at both the constitutional and statutory levels. Significant in this respect are the provisions of Article 61(3) and Article 31(3) of the Constitution of the Republic of Poland of 2 April 1997 and Article 5 of the Act of 6 September 2001 on access to public information. Paragraph 2b of Article 5 of the Law on Access to Public Information indicates a specific type of restriction related to the regulations of the Law of February 12, 2010 on the Recapitalization of certain institutions and governmental financial stabilization instruments. The focus of the deliberations conducted has been centered on detailing the essence and nature of this limitation.
The Effects of the Action of Chromium, Aluminum, Nickel and Iron on Human Fibroblast and Stem Cell Cultures
Authors: Górska Aleksandra , Markiewicz-Gospodarek Agnieszka , Chilimoniuk Zuzanna , Kuszta Piotr , Czarnek Katarzyna
Published: December 2022

This review is a collection of general information about chromium, aluminum, nickel and iron. We tried to include not only the data about absorption, metabolism, interactions with other elements and the importance of those microelements in the human body but also their toxic and mutagenic effects. Moreover, we examined their effect on human fibroblast and stem cell cultures which may be important due to abuse of supplementation in the population nowadays.
ENVIRONMENTAL IMPACTS OF SWINE FARMING
Authors: De Brito Soraya Abrantes Pinto , Duarte Grazielly Diniz , Sobral Felipe Eduardo da Silva , Christoffersen Martin Lindsey
Published: December 2022

In this study we carried out bibliographical research on the impacts that pig production can cause on the environment, highlighting what is necessary for its production. During the research, some current manuscripts on this theme were used in the Google Scholar tool. Brazil is the fourth largest producer and exporter of pork. Despite the importance of this activity, the environmental impacts linked to swine farming have caused extremely relevant effects on the surrounding environment. The high consumption of water resources and the emission of liquid and gaseous objects into the environment are notable among these effects. The undue discharge of untreated waste into rivers, lakes and the soil can cause diseases (worms, allergies, hepatitis), in addition to zoonoses, causing discomfort to the population. The objective of this work is to identify environmentally sustainable alternatives with regard to the disposal of manure and the waste of water from pig farming. Swine farming requires a waste control program for its correct management. Waste treatment, in order to fulfill its final objective and to be effective, needs to convert waste into harmless material when returned to the environment. We have biodigesters as a form of treatment that is an efficient tool contributing to the minimization of waste that goes into the environment.
The Instrument Construction for Students' Religious Moderation: Psychometric Analysis
Authors: Halik Al , Khumairo Aisyah , Yawisah Umi
Published: December 2022

Religious moderation is becoming a prevalent focus to achieve social harmony and peace, preventing extremism, intolerance, and acts of violence. The current study aims to investigate the psychometric properties of an instrument measuring students' religious moderation attitudes. The research method used is the quantitative construction of measuring instruments. The scale development indicator uses the four dimensions of religious moderation developed by the Indonesian Ministry of Religion. The scale development procedure involved 10 experts consisting of academics and employees of the Metro City Ministry of Religion. 135 Respondents for the instrument trials were drawn using a random sampling technique, taking into account students of IAIN Metro in semesters 3, 5, and 7 who were still active. The results show that based on the consistency value of experts, which is known through the interquartile range (Q), there are 60 items out of 78 declared significant. The content validation category based on Aiken's V count is 0.693, which is interpreted as a moderate category. The items have been validated by experts and fulfilled the discriminatory power criteria according to the psychometric analysis prerequisites. Based on the validity test results, using the baseline correlation on 60 items, 36 items fulfilled the validity level. Reliability testing shows a coefficient of 0.800 (reliable) means that this scale is consistent. These findings are expected to benefit the measurement of students' religious moderation attitudes and serve as a need assessment in the establishment of regulations and policies in higher education.
Sexual Orientation and Identification of Islamic Guidance and Counseling Approaches to Lesbian in Rejang Lebong
Authors: Verolyna Dita , Yusro Ngadri
Published: December 2022

The current study aims to determine the factors that cause women to become lesbians and Islamic counseling guidance methods for lesbians. This study uses a qualitative method with a phenomenological study approach. A total of four lesbians, two butch and two femme lesbians, voluntarily participated in this study at Rejang Lebong in 2021. The data were collected through in-depth interviews. The research results revealed that there are several factors that cause women to have homosexual orientation; biological factors, life trauma, environmental support, lack of religious knowledge and lack of attention from parents. Analyzed using the self-disclosure theory, the results showed that femme lesbians tended to be shy and introverted, so the approach was taken individually and personally. In contrast, butch-labeled lesbians are more open so that they can be done in groups. The decision to become a lesbian is not caused by a single factor but a combination. However, only femme-labeled lesbians are caused by a life trauma. This research only focuses on the causes of being a lesbian and appropriate Islamic counseling guidance approach techniques based on the type of lesbian. This study did not look at the final product after counseling was carried out. It is recommended for future studies to investigate concrete steps of Islamic counseling guidance for lesbians.
Kur’ân’daki “Nefislerinizi Öldürün/Öldürmeyin” (اقتلوا/لاتقتلوا انفسكم) İfadelerine Dair Bir Değerlendirme
Authors: YAKAR Hüseyin
Published: December 2022

Kur’an’da “ktl” (قتل) fiilinin emir veya nehyiyle “enfüseküm” lafzının buluştuğu ayetler tefsir kaynakları ve meallerde farklı yorumlanmaktadır. Çalışmamızda söz konusu buluşmanın görüldüğü وَلَا تَقْتُلُٓوا اَنْفُسَكُمْۜ “nefislerinizi öldürmeyin”, ثُمَّ اَنْتُمْ هٰٓؤُ۬لَٓاءِ تَقْتُلُونَ اَنْفُسَكُمْ “sonra işte sizler nefislerinizi öldürüyorsunuz (öldürmeyin)”(en-Nisâ 4/29, el-Bakara 2/85) nehiyleri ile اقْتُلُٓوا اَنْفُسَكُمْ “nefislerinizi öldürün” (el-Bakara 2/54, en-Nisâ 4/66) emirlerinin nasıl yorumlandığı ve yorumlanması gerektiği ele alınmıştır. Anlam yakınlıklarına bağlı olarak ilgili ayetler emir ve nehiy kipleri olmak üzere iki başlıkta tasnif edilmiştir. Söz konusu ifadeler kapsamında öncelikle tefsir kaynaklarımız üzerinden bilgi aktarılmıştır. İlgili bölümde tefsir kaynaklarımızdaki veriler daha çok tasvir metoduyla ortaya konulmuş, yer yer bazı görüşler ile ilgili tarafımızca değerlendirmelerde bulunulmuştur. Araştırmamızın son bölümünde ise ilgili ifadeler tarafımızca değerlendirilmiştir. Zikri geçen ayetler değerlendirilirken emir ve nehiy olmak üzere ikişerli olarak dört ayetin anlam bakımından bütünselliği, Kur’an’da “enfüs” lafzının mef'ûl makamında olduğu ayetler, ilgili ayetlerin siyak-sibak bakımından durumu, sebeb-i nüzule dair rivayetler, olgusal gerçeklik ve Tevrat verileri dikkate alınmıştır.
İbn Sînâ Felsefesinde Ahlaki Öznellik
Authors: KILIÇ Emrullah
Published: December 2022

Sembolik hikâyeler, felsefî üslûp içinde önemli bir anlatı biçimi olarak karşımıza çıkmaktadır. Sembolik hikâyeyi yazanlar, alışılagelmiş kavramsal karşılıklar yerine, kullanımına bağlı olarak olguları kendine özgü başka anlamlara dönüştürmektedir. Bu bağlamda İbn Sînâ da ahlâkî öznelliğe dair temellendirmelerini daha çok sembolik hikâyeler üzerinden ortaya koyar. İbn Sinâ, nefs teorisine bağlı olarak inşa ettiği ahlâkî görüşlerini sembolik dilin yaratıcılığı ile genişleterek makullük-rasyonellik formatının sınırlarına taşımıştır. Bu bağlamda İbn Sînâ kendinden önceki pek çok filozofun yaptığının aksine olgusal gerçekliği sadece kavramsal analizlerle izâh etmemiş onun öznenin potansiyeline uygun biçimde yorumlanmasına olanak sağlamıştır. Nesneleştirmeden ziyade sembolik bir yaklaşımla ahlâkî öznelliğini inşa etmeye çalışan filozof bu bağlamda ilkelere yönelerek bunu “yolculuk” üzerinden temellendirmiştir. Bu bağlamda hikâyeler, hikâyede anlatılan olayları aşan bir ufuk ile varlığın idraki üzerine kurulu tecrübeyi seslendirir. İbn Sînâ’nın Hayy b. Yakzan, Salaman ve Absal ve Et-Tayr hikâyelerini merkeze alan çalışmamız, nihai anlamda onun ahlâkî görüşlerinin bugün ihtiyaç duyulan çoğulcu ve bütünlükçü ahlâkî yapılara ufuk verebileceğine işaret etmektedir.
İslam Aile Hukukunda Aile Hakemliği ve Günümüzdeki Aile Problemlerinin Çözümünde Uygulanabilirliği
Authors: KAŞDİBİ Ahmet , YILMAZ Sinan
Published: December 2022

Bu çalışmada, günümüz hukuk sistemlerinde uygulanmakta olan aile arabuluculuğu ile İslam kültürünün etki alanında olan toplumlarda tarih boyunca uygulanmış olan aile hakemliği uygulamaları karşılaştırmalı olarak incelenmeye çalışılmıştır. Araştırmanın genelinde İslam dinindeki arabuluculuk uygulamaları ile ilgili olarak öncelikle İslam dininin temel dayanakları olan ayet ve hadislerde yer alan hükümler ile bu hükümlere dayalı olarak İslam’daki farklı mezhepler tarafından ortaya atılan arabuluculuk çözümlerinin neler olduğu incelenip tartışılmıştır. Aile arabuluculuğu yönteminin İslam Aile Hukuku’ndaki temel uygulaması olan “Aile Hakemliği” müessesesi de ayrıca ele alınmıştır. Araştırmada ailede ortaya çıkan sorunlar değerlendirilirken toplumun eşler arasında ortaya çıkan sorunlar ve çözüm yolları ile ilgili düşünceleri de nicel verilerle desteklenmeye çalışılmıştır. Araştırmanın temelini oluşturan İslam kültüründeki aile hakemliği müessesesinin tarihsel gelişimi ve mezheplerin görüşleri ele alındıktan sonra aile hakemliği müessesesinin günümüz koşullarında uygulanabilirliği tartışılmıştır. Araştırmada ayrıca hakemlerin görev ve yetki sınırlarının neler olduğu konusuna da değinilmiştir.
Recent Advances in Advance Prostate Cancer
Authors: Lohia Nishant
Published: December 2022

Prostate cancer being the second most frequent and fifth leading cause of mortality has led to conduct of many new clinical trials and development of newer therapeutic agents. In the last decade with better understanding of biology of disease there is dramatic improvement and sea change in survival outcomes in advanced prostate cancer with advent of chemotherapy, targeted therapy immunotherapy besides androgen deprivation therapy. Varied newer drugs and combinations in recent years have improved the outcome of prostate cancer in terms of both overall survival(OS) and metastases free survival(MFS). Some of the latest drugs which have cleared regulatory approval are Abiraterone, Enzalutamide,Apulatamide, Sipuleucel-T etc. However still more needs to be explored to negate and overcome the resistant mechanisms. Here in this article we have summarized the varied newer and recent developments in advanced prostate cancer.
COVID-19 Vaccine and Bladder Cancer: Friend or Foe?
Authors: Qi Kevin Z. , Palomino Miriam P. , Murray Justin D. , Agee Madeline N. , Wakefield Mark R. , Fang Yujiang
Published: December 2022

This is a letter to the editor on the discussion on COVID-19 vaccine and bladder cancer.
Korunma Motivasyonu Kuramı Kapsamında Sırtçantalıların Gıda Güvenliği Davranışları
Authors: CUMHUR Öznur , BİNGÖL Serhat
Published: December 2022

Seyahat esnasında tüketilen yiyecek ve içeceklerin güvenli olması seyahat deneyiminin önemli bir parçasıdır. Gezginler seyahatleri sırasında gıda seçim kararları ve tüketim davranışları sebebiyle potansiyel gıda tehlikeleriyle karşı karşıya kalmaktadırlar. Gezginlerin yiyecek ve içeceklere yönelik davranışlarını açıklamak ve tahmin etmek için çeşitli teorik modeller kullanılabilir. Bu modeller içerisinde korunma motivasyonu kuramı kapsamlı olarak ön plana çıkanlardan bir tanesidir. Korunma motivasyonu kuramı korku çekiciliği ve tutum değişikliği arasındaki boşluğu incelemek için geliştirilen ve sağlık davranışı alanı başta olmak üzere, risk içeren birçok alanda kullanılan bir modeldir. Model riskli durumlarda tutum ve davranış değişikliğinin nedenini anlamak için bir çerçeve sunar. Kavramsal bir çalışma olan bu araştırmanın amacı, gezginlerin maruz kaldığı gıda kaynaklı riskleri sunmak ve gezginlerde güvenli gıda tüketimi için korunma motivasyonu kuramının nasıl kullanılabileceğini araştırmaktır. Bu kapsamda korunma motivasyonu kuramı sırt çantalı gezginler özelinde değerlendirilmiş ve güvenli gıdaya erişim noktasında sürece nasıl destek olacağı tartışılmıştır. Bu tartışma sonucunda, korunma motivasyonu kuramı ile sırt çantalı gezginlerin gıda riskleri karşısındaki niyet ve davranışlarının tahmin edilebileceği ve yönlendirilebileceği anlaşılmıştır. Kuramın risk iletişim sürecinde kurum ve kuruluşların gıda riskleri karşısında sunduğu koruyucu önlemleri desteklemek için de kullanılabileceği ortaya koyulmuştur.
Penerapan Konsep Internet of Things pada Pengembangan Aplikasi Portal Alumni di Universitas Terbuka
Authors: Arif Erman , Julianti Eka , Paulina Soko Imelda
Published: December 2022

Internet of things merupakan salah satu pilar dari Industri 4.0 sehingga kompetensi akan konsep dan praktiknya merupakan hal yang sangat berguna. Dunia pendidikan tidak bisa eksis tanpa alumni, namun keberadaan mereka seringkali terdokumentasi dengan buruk sehingga menimbulkan kesenjangan antara data alumni dan keadaan sebenarnya. Banyak program studi di Universitas Terbuka setiap tahun meluluskan ribuan mahasiswa. Karena UT saat ini belum memiliki portal alumni seperti kebanyakan universitas lainnya, sulit untuk mencari data dan informasi tentang alumni dan komunikasi antar alumni tidak berjalan dengan baik setelah lulus. agar alumni dapat berkomunikasi secara efektif dan bertukar informasi melalui Portal ini. Sehingga dengan adanya Portal ini alumni dapat berkomunikasi dengan baik dan dapat bertukar informasi. Saat ini Alumni UT hanya bertukar informasi melalui social media seperti WhatsApp Group, Facebook, dll. Dan hal tersebut belum bisa dikontrol oleh UT. Oleh karena hal tersebut diperlukan sebuah Portal yang mampu menjadi solusi dari permasalahan tersebut. Studi ini bertujuan untuk membuat sebuah Portal Alumni dengan penerapan Internet of Things dalam bentuk sebuah website online menggunakan metode Research and Development (R&D). Pengembangan aplikasi dibatasi sampai dengan prototipe karena untuk penerapan diperlukan studi lebih lanjut.
Evaluasi Tingkat Kepuasan Mahasiswa Terhadap Pelayanan Akademik Menggunakan Metode Klasifikasi Algoritma C4.5
Authors: Widiastuti Tri , Karsa Koko , Juliane Christina
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh layanan akademik terhadap kepuasan mahasiswa agar mahasiswa tidak merasa kecewa terhadap pelayanan akademik. Penelitian ini melakukan pengukuran tingkat kepuasan mahasiswa terhadap layanan akademik yang ada pada Universitas Jenderal Achmad Yani Cimahi. Data set hasil survey kepuasan mahasiswa terhadap layanan akademik di Unjani ini digunakan untuk menghasilkan model, rule dan nilai akurasi  kepuasan mahasiswa  dengan menggunakan metode klasifikasi data mining algoritma Decision Tree C4.5, untuk melihat hasil nilai akurasi dari beberapa atribut yaitu tangible, empaty, responsiveness, reliability dan assurance. Hasil dari dari pengujian yang dilakukan dengan aplikasi rapidminer nilai akurasi dari pengujian 7 (Tujuh) Fakultas di Unjani menghasilkan nilai diatas 90% yang artinya nilai tersebut menandakan bahwa pelayanan yang sudah berjalan selama ini dianggap sangat baik. Pengujian survei kepuasan mahasiswa tentunya harus dilakukan secara periodik untuk dapat terus meningkatkan pelayanan akademik kepada mahasiswa  menjadi semakin baik.
Performance Measurement Design as a Company Performance Improvement Strategy Using the Balanced Scorecard Method
Authors: Al Qadri Diaz , Effendy Lukman , Astuti Widia
Published: December 2022

This research purposes to determine the performance of PT XX and what strategies can be implemented to improve the company's performance. This research uses a qualitative approach with descriptive analysis on case studies. The types of data used in this research are primary and secondary data as well as qualitative descriptive data analysis techniques. From the research results obtained by researchers, performance measurement using the balanced scorecard method can be concluded that researchers get several variations of the results. From a financial perspective, the company's ROA and NPM ratios show good results, the customer perspective which has been measured by the level of customer satisfaction and customer profitability also shows good results
Teaching marine engineering terms through online methods in maritime training courses
Authors: Smirnov Igor Olegovich , Dokuto Bozhena Borisovna , Kondratiev Alexey Ivanovich
Published: December 2022

Verbal communication is an integral part of seafarers’ professional activity and a compulsory condition of vessels’ safety, the prevention of marine environment pollution, the fulfillment of international and national legislation in the field of sea transport, and the organization and management of sea transport traffic involving multinational crews. The present study contributes to the resolution of professional communication linguistic support problems within the framework of the marine engineer’s activities. Additionally, it ensures safety at sea by developing the terminological component of the foreign-language competence of marine engineers. The purpose of the research presented in this article is to identify patterns of teaching the English maritime engineering term system used in oral professional communication and technical documentation engaging the Moodle Platform. The concept of marine engineering terminology, as well as the principles of distinguishing it from a more general concept of «maritime terminology», was considered in order to achieve this goal. The article suggests a combination of the most efficient Moodle tools that can be used to develop trainees’ specific terminological competence.
Highlights 

A comprehensive analysis has allowed identifying differences in the functioning of ship engineering terms in technical documentation and oral professional communication
The elements of this terminological system under analysis form hierarchical paradigms
The functioning of ship-engineering terms in professional communication is complicated by the presence of synonyms within the terminological system and pseudo-international vocabulary
Marine engineering terms can be successfully taught through a combination of several Moodle instruments, which enables trainees to conduct comprehensive structural-semantic comparative analysis of the English ship engineering terminological system
Mathematical model to assess energy consumption using water inflow-drainage system of iron-ore mines in terms of a stochastic process
Authors: Sinchuk Oleg , Strzelecki Ryszard , Sinchuk Igor , Веridzе Теtуаnа , Fedotov Vladyslav , Baranovskyi Vladyslav , Budnikov Kyrylo
Published: December 2022

Purpose is to develop a unified mathematical model to assess energy efficiency of a water inflow-drainage process as the real variant of stochastic method for water pumping from underground workings of iron-ore mines. Methods. The research process was based upon the methods of probability theory as well as stochastic modelling methods. The stochastic function integration has been reduced to summation of its ordinates and further transition to a proper boundary. Findings. A mathematical model of a water inflow-drainage system as a stochastic process has been developed in terms of input parameters of a standard operating iron-ore mine. The abovementioned has made it possible to assess realistically, substantiate, and obtain possibilities for a specific production facility as well as for generalization of the results involving determination of stochastic characteristics of drainage process. Originality. For the first time, a mathematical model of drainage from underground levels of iron-ore mines has been developed as a stochastic process. The process characteristics have been identified relying upon randomness of a water pumping technique. In contrast to the available settings, the new model parameters characterize their dispersion. Possibility to obtain complete characteristics of energy consumption has been obtained: for drainage; for water accumulation volume in underground water collectors; for water pumping from the specified mine depths over the specific period as random processes. A number of drainage features have been analyzed and differentiated being determined with the help of nor-mal law of water accumulation velocity in the underground water collectors in iron-ore mines. Practical implications. In terms of operating iron-ore mine, a generalized drainage mathematical model has been developed as a stochastic process using statistical data concerning water accumulation velocity in the underground water collectors. It has been proved that if the ordinates of water accumulation velocity in the underground water collectors obey the normal distribution law then it is expedient to characterize drainage as a stochastic process. The developed methods, studying drain-age as a stochastic process, help expand the research boundaries involving other auxiliary operations performed during underground mining of iron ore raw materials.
Analytical and numerical study of one-dimensional and two-dimensional stress distribution within an elastic semi-infinite material under the action of an arbitrary rectangular uniform loading
Authors: Maleki Farid Sh , Chakeri Hamid , Chehreghani Sajjad , Soula Hossein Azad
Published: December 2022

Purpose. The study of stress distribution within an elastic semi-infinite material under the action of an external loading is of great importance in the theory of elasticity. In most cases, the lack of knowledge about the stress distribution within a material can result in incomplete and inappropriate engineering designs, leading to unsatisfactory consequences. The latter include cracks and fractures, created inside the concrete segmental lining in TBM tunneling, as well as indentations that occur in floors due to the lack of pillar design not only in underground mining, but even in civil projects. This study focuses on the one-dimensional and two-dimensional internal stress distribution induced by arbitrary rectangular–square loading, in other words, that applied to an elastic semi-infinite material. Methods. Firstly, this paper uses an analytical method and, subsequently, a numerical method. In the analytical study, the point load equations of Boussinesq and Westergaard are used. Extending these equations to the rectangular loading area, four new equations are introduced. Using the Abaqus finite element software, the numerical study is performed in 3D space. Findings. The results show that the answers from the introduced equations are in high consistency with numerical ones. However, the result of the extended Boussinesq point load equation is closer to the answer obtained by the numerical method. Originality. Four new equations, presented in this paper, describe one-dimensional and two-dimensional stress distribution. Practical implications. The presented equations can provide a simple and convenient way to solve rectangular load problems in many cases such as foundation, civil and mining projects. This study uses initial information on specific segments in the Tabriz Metro line-2 Project.
Slope failure characterization: A joint multi-geophysical and geotechnical analysis, case study of Babor Mountains range, NE Algeria
Authors: Boubazine Leila , Boumazbeur Abderahmene , Hadji Riheb , Fares Kessasra
Published: December 2022

Purpose. The research purpose is to apply an original combined approach to the study of landslide occurrence in the Tarzoust region, based on geophysical approaches. This is extremely important because landslides damage roads and buildings in many parts of North Africa, especially in the city of Tarzoust, NE Algeria. Significant slope failures have resulted in serious disasters in the region. Methods. In this study we use Vertical Electric Soundings (VES) and Seismic Refraction Method (SRM) for underground exploration, as well as Electrical Resistivity Tomography (ERT) to support the latter two methods. Findings. The clayey nature of the terrain is confirmed, very often covered by a mantle of superficial colluvium formations. The depth of the bedrock and shear surface has been precisely determined. The ERT reveals that the terrain has already experienced instability in the past. Originality. The originality of this study is in the combination of data from various sources and different approaches for the purpose of planning the deployment and use of land. Practical implications. Our approach has proven that the combination of geological and geotechnical data with geophysical deterministic methods can help engineers and decision-makers in land management. Our recommendations consist of topographic, inclinometric and piezometric monitoring for slip development and the effectiveness of reinforcement measures for new housing, and equipment programs for regional planning.
The Reve’s Puzzle with single relaxation of the Divine rule
Authors: Majumdar Abdullah Al Kafi
Published: December 2022

This paper proposes a new version of the Reve’s puzzle, allowing at most one violation of the “divine rule”. Letting S(n) be the minimum number of moves required to solve the problem with n(³ 1) discs, an scheme is given to find the dynamic programming equation satisfied by S(n). A closed- form expression of S(n) is derived.
J. Bangladesh Acad. Sci. 46(2); 213-217 December 2022
Iron (II) and Zinc (II) complexes of gemifloxacin mesylate: synthesis, characterization, serum binding profiling, and evaluation of antimicrobial activity
Authors: Aktar Fahima , Hossain Md Jamal , Sultan Md Zakir , Rashid Mohammad A
Published: December 2022

Gemifloxacin mesylate is a synthetic fluoroquinolone derived antimicrobial    agent. Two metal complexes of gemifloxacin mesylate were synthesized viz. gemifloxacin-Fe and gemifloxacin-Zn. The formed complexes were characterized by using TLC, TGA and FT-IR spectra analyses. The formed complexes were then evaluated for antimicrobial activity. The newly formed two complexes were assessed against nine bacterial and one fungal strain, where gemifloxacin (30 µg/disc) was used as a reference standard. The new complexes showed better activity than the standard reference drug against Klebsiella pneumoniae among nine bacterial strains. But two bacterial species, Acinetobacter lwoffii and Enterococcus faecium, and the fungal strain Candida albicans showed complete resistance to the newly synthesized complexes and the reference standard.  The drug protein interaction with the Bovine Serum Albumin (BSA) was also studied. The interaction mechanism was explored, suggesting that gemifloxacin and its Zn (II) complex interact with BSA via a static process while the Fe (II) complex interacts via a dynamic process and the lower Ksv value also indicated that drug -BSA complexes were formed in ground-state.
J. Bangladesh Acad. Sci. 46(2); 203-211: December 2022
Clinical Presentation and Outcome of Management of Congenital Heart Diseases Associated with Down Syndrome in a Tertiary Care Hospital
Authors: Ferdous Jannatul , Begum Nurun Nahar Fatema , Rashid Md Harun Or
Published: December 2022

Introduction: Treatment of children with Down syndrome having congenital heart defects has not been reported well in Bangladesh. This study has been carried out to inform practitioners about findings from cases in Combined Military Hospital, Dhaka.
Methods: Three years retrospective observational study (clinical data, hospital course and follow-up) was carried out on 114 patients (49 males and 65 females, age range 1 month to 12 years) who underwent diagnostic and therapeutic work up in the pediatric cardiology department CMH Dhaka between January 2018 and December 2020.
Results: Among 114 patients ,64 were (57%) were infants and 50 were older children (43%) , twenty-five had congestive cardiac failure and eighteen had hypothyroidism. The study showed that 33.3% were atrioventricular septal defect (AVSD), 28.1% were patent ductus arteriosus (PDA),8.75% were tetralogy of Fallot (TOF) ,5.25% were coartation of aorta (COA) ,3.5% were patent ductus arteriosus with coarctation of aorta 3.5%, double outlet right ventricle with pulmonary stenosis were 3.5%, ventricular septal defect were 7% whereas atrial septal defect along with ventricular septal defect were 5.3% ,atrial septal defect were 3.5%, transposition of great arteries with multiple ventricular septal defect were 1.8%.Forty (35%) patients using per cutaneous intervention,had 100% procedural success and no mortality .45 patients underwent surgery,few of them were not operated due to severe pulmonary hypertension.
Conclusion: Congenital heart disease was more frequent in DS children,having worse prognosis.Children with DS required special attention due to increased risk of pulmonary hypertension. Delayed treatment was an important risk factor for poor prognosis.So early diagnosis is needed in order to provide optimal intervention and surgery ,before occurrence of irreversible PAH.
J Bangladesh Coll Phys Surg 2023; 41: 7-14
PENINGKATAN PENDAPATAN UMKM DI KELURAHAN TEMBESI DENGAN PENDAMPINGAN DAN PENYULUHAN METODE PEMASARAN PADA MASA PANDEMI COVID-19
Authors: Nurlaila Qomarotun , Siketang Faradila Ramadhani , Nainggolan Aliato , Rezki Muhammad , Siahaan Natal Wijaya , Sirait Cristi Romauli
Published: December 2022

Tujuan dari pelaksanaan kegiatan pengabdian ini adalah untuk meningkatkan pendapatan UMKM di kelurahan Tembesi dengan melakukan pendampingan dan penyuluhan tentang metode pemasaran pada masa pandemi Covid-19. Metode yang digunakan adalah dengan melakukan pengecekan langsung masalah yang dihadapi oleh pelaku UMKM. Mitra dari kegiatan pengabdian masyarakat adalah enam pelaku UMKM di Kelurahan Tembesi yaitu Es campur, Distera taylor, tempe mendoan, warung makan, empek-empek, rujak. Pendapatan dari para mitra pelaku UMKM terpengaruh oleh pandemi Covid-19. Semua pelaku belum melakukan promosi dengan media sosial, sedangkan di masa pandemi Covid-19 mayoritas masyarakat mengurangi kegiatan diluar dan melakukan pembelian secara online. Pelaku UMKM yang bergerak dibidang makanan dan minuman, mayoritas belum memperhatikan kemasan dan tidak menggunakan label sebagai identitas dari pelaku UMKM. Dalam proses pendampingan dan penyuluhan mayoritas pelaku UMKM mengikuti arahan dari pelaku pengabdian masyarakat, meskipun ada 2 pelaku UMKM yang tidak bersedia menerapkan promosi dengan media sosial yaitu UMKM tempe mendoan dan rujak. Secara keseluruhan, pelaksanaan pengabdian masyarakat memberikan perubahan positif terhadap pendapatan pelaku UMKM.