bluuebunny/crossref_metadata_2025 huggingface dataset:
Development evelopment and use of resistance and immune status indices in pig breeding
Authors: Fedyuk Victor V. , Chertov Arkadi A.
Published: January 2021

Relevance and methods. Selection indices for indicators of natural resistance (NR) and immune status (IS) have been proposed. To assess the state of pig natural resistance, 8 indicators that reflect the state of four protective properties of blood have been studied. They are: bacteriostatic, antigen-binding, bacteriolizing and phagocytic. To assess the immune status, a set of standard and unified tests of the first and second levels has been developed.

Results. The first includes rosette formation reactions for quantitative determination of T- and B-lymphocytes, determining Ig G, Ig A, and Ig M count in blood serum by radical immunodiffusion (RID) in gel, and quantitation of active phagocytes from neutrophilic granulocytes in reaction with inert particles of melamine-formaldehyde latexes. Tests of the second level of immune status assessment include determining the number of T-lymphocytes of various subpopulations in the lymphocytotoxic test. The pig population has been evaluated and young animals have been selected according to the resistance index in order to increase resistance to conditionally pathogenic microflora.
Spring barley initial forms for breeding on productivity in the Middle Volga region’s conditions
Authors: Stolpivskaya Evgeniya V.
Published: January 2021

Relevance. Evaluation of initial forms for breeding is one of the stages of the selection process. The global gene pool of spring barley (Hordeum vulgare L.) is replenished annually with hundreds of new varieties containing a different combination of genes. In this regard, it is relevant to constantly study accessions of different geographical origins according to various criteria, including productivity indicators. The research was conducted to identify genotypes for creating a new highly productive breeding material for spring barley.

Methods. The objects of study were 59 accessions of spring barley (Hordeum vulgare L.), represented by forms from Russia, CIS countries, Europe and the USA. The study of the initial forms was carried out according to The guidelines for the study of the collection of barley and oats (VIR, 1981).

Results. As a result of the study of the spring barley initial material in condition of the Samara region (Kinel) in 2017-2019, 22 varieties were identified that are characterized by consistently high values of productivity indicator: Signal (K-30846, Altai region), Anna (K-30829, Orenburg region), T-12 (K-30990, Orenburg region), Lun’ (K-31101, Penza region), Vityaz (Samara region) — by the value of the indicator “weight thousand grain” above 40 g, recommended as sources for creating breeding material with high values of this criterions. The following varieties are recommended as sources for breeding work to increase the weight of 1000 grains, productive bushiness and plant productivity in the Middle Volga region: Veles (K-30982, Belgorod region), Volgar (K-29831, Samara region), Orlan (Samara region), Omsky 90 (K-30721, Omsk region) and Sasha (K-31110, Omsk region), Charivny (K-31063, Ukraine), KWS Tessa (Germany), AC 06/659/48/2 (Denmark), local (K-9267, Turkey).
Formation of grain quality of new varieties of spring soft wheat in the middle volga region
Authors: Kincharov Alexander I. , Mullayanova Olga S. , Demina Elena A. , Taranova Tatyana Yu. , Chekmasova Kristina Yu.
Published: January 2021

Relevance. The article presents the results of studying the formation of grain quality indicators in varieties of competitive testing of spring soft wheat. The purpose of the research is to study local new varieties of spring soft wheat according to the most important quality indicators for the middle Volga region and to identify varieties that consistently form high grain quality for further breeding and seed production.

Materials and methods of researches. The object of research was 36 varieties of spring soft wheat of competitive testing, created in the Volga Scientific Research Institute of Selection and Seed-Growing named after P.N. Konstantinov. The study of varieties was carried out according to the Methodology of the state variety testing of agricultural crops (1985). Grain quality indicators were determined according to current standards.

Results. The greatest variability over the years was observed in the indicators of grain vitreous (CV = 5.40–10.0%), protein content (CV = 3.75–10.48%) and gluten content (CV = 7.62–10.20%), that is, in indicators that depend on growing conditions. As a result of a comprehensive assessment of varieties, valuable sources are identified that annually form high-quality grain. These are the Kinelskaya 59, Kinelskaya niva, Kinelskaya 2010, Kinelskaya yubileynaya varieties included in the register, the Kinelskaya Zarya variety undergoing State testing, and the new promising lines Erythrospermum 3898, Erythrospermum 4112, Erythrospermum 4171, Erythrospermum 5289, Lutescens 6029. The varieties that were selected during the study are recommended for use in breeding programs for creating high — quality forms for contrasting weather conditions, zoned varieties — for wide use in commodity production, new lines-for preparation and transfer to State testing
Study of the contribution of horizontal stability in the probability model of the “hostpathogen” interaction system on the basis of millet varieties susceptible to smut
Authors: Vilyunov Sergey D.
Published: January 2021

Digital control of breeding process, creation of mathematical models of living objects and management of plant life cycle is an urgent problem of modern times. Сreation of technologies that ensure implementation of the concept of advanced digital "smart" agriculture is impossible without basic mathematical models of "mass interactions" of natural living objects. This primarily affects the spread of certain diseases in populations. In the plant world, such a convenient model object is the well-studied "host-pathogen" system by the example of the interaction of millet and its smut disease. At present, the knowledge of the patterns of development of this disease in the millet plant is of a qualitative nature (virulence), and the quantitative characteristics (aggressiveness) are approximate. Only mathematical modeling of this process can accurately describe the development of the disease. This paper examines a probabilistic model and certain aspects of mathematical modeling using the example of identifying the laws of horizontal resistance to smut in susceptible millet genotypes.
Qualidade de Vida e Estratégias de Enfrentamento em Mulheres com e sem Linfedema Pós-Câncer de Mama
Authors: Alegrance Fabia Cristina , Souza Camila Bernardes de , Mazzei Ricardo Lencioni
Published: January 2021

O linfedema, complicação do tratamento de câncer de mama, pode levar às limitações físicas, funcionais, psicológicas e sociais. O objetivo deste estudo foi verificar o impacto do linfedema nos fatores biopsicossociais das portadoras, identificando as estratégias de enfrentamento e avaliando a qualidade de vida de mulheres com e sem linfedema após câncer de mama. Os instrumentos de avaliação foram: questionário de caracterização; questionários de qualidade de vida European Organization for Research and Treatment of Câncer (EORTC) QLQ-30 e BR-23; e Inventário de Estratégias de Coping. Foram entrevistadas 82 mulheres, idade média de 57,4 anos (DV12,3), submetidas ao tratamento de neoplasia mamária. O linfedema apresentou-se em 39,03% e parece não interferir muito na qualidade de vida dessas mulheres, sendo a função social a mais prejudicada. Nas portadoras de linfedema, apenas os sintomas relacionados aos braços foram estatisticamente maiores, e o autocontrole foi a estratégia de enfrentamento estatisticamente mais utilizada. Outras estratégias utilizadas foram: reavaliação, resolução de problemas, fuga, suporte social e autocontrole. Conclui-se que o uso de estratégias ativas e positivas para enfrentar o câncer de mama parece resultar na boa adaptação psicossocial.
Adenocarcinoma de Tuba Uterina: Relato de Dois Casos
Authors: Sousa Rodrigo Beserra , Lages Rafael Bandeira , Pereira Filho Edgard , Santos Lina Gomes dos , Vieira Sabas Carlos
Published: January 2021

Os tumores malignos primários de tuba uterina são os menos frequentes do aparelho genital feminino, correspondendo de 0,1 a 0,5% do total desses tumores. O pico de incidência é em torno dos 60 anos. Devem-se aplicar critérios muito rigorosos para considerar uma lesão neoplásica primária da tuba, pois a proximidade da mucosa endometrial e do ovário dificulta o diagnóstico. O primeiro caso é de uma paciente de 44 anos de idade que se submeteu à laparatomia por apresentar um tumor pélvico. Identificou-se uma massa na tuba uterina direita, realizando-se histerectomia total com salpingectomia direita, ooforectomia esquerda, preservando-se o ovário direito. O histopatológico demonstrou adenocarcinoma pouco diferenciado na tuba direita, bem como a presença de dois focos metastáticos no ovário esquerdo. Iniciou-se quimioterapia adjuvante. Após seis ciclos, notaram-se lesões pélvica e para-aórtica, além de lesão de cúpula vaginal. A paciente submeteu-se à ooforectomia direita e linfonodectomia pélvica e para-aórtica, não havendo doença neoplásica no estudo histológico dos espécimes. O segundo caso é de uma paciente de 63 anos de idade com uma lesão cística em anexo uterino esquerdo e mista em anexo direito. Submeteu-se a uma cirurgia sendo realizada salpingooforectomia bilateral. Ao histopatológico, evidenciou-se adenocarcinoma de tuba moderadamente diferenciado em tuba direita. Após esse diagnóstico, fez-se histerectomia e omentectomia, que não apresentaram doença no histopatológico. Ambas as pacientes encontram-se bem e sem evidência de doença neoplásica em atividade, 40 e 72 meses após a primeira cirurgia, respectivamente.
O Percentual de Fragmentos Acometidos na Biópsia como Preditor da Extensão do Câncer de Próstata: Revisão Sistemática
Authors: Andrade Rógerson Tenório de , Pontes Filho Nicodemos Teles de , Lucena Roberto Gonçalves de , Santos Jr. Misael Wanderley , Lima Salvador Vilar Correia , Silva Vilma Maria da
Published: January 2021

O objetivo do presente estudo foi realizar uma revisão sistemática de estudos que avaliaram a associação do percentual de fragmentos acometidos por câncer na biópsia prostática com a extensão tumoral na peça cirúrgica. Com base em estratégia de revisão sistemática do programa de pós-graduação da Universidade Federal de Pernambuco, foram identificadas 979 publicações nas bases de dados: PubMed, Lilacs, SciELO e Medline; entre as quais, por um conjunto de critérios de inclusão/exclusão, foram selecionados 20 artigos publicados entre 2000 e 2009. Em 13 artigos, o percentual de fragmentos acometidos foi considerado como um excelente preditor do estadiamento cirúrgico. Em dois trabalhos na literatura, os autores sugeriram dois pontos de corte diferentes (“cut-off”), de 33% e 37,5%, no percentual de fragmentos acometidos para a estratificação de doença extraprostática em baixo e alto riscos. Concluiu-se que o percentual de fragmentos acometidos na biópsia prostática é uma ferramenta importante na avaliação prognóstica do paciente, e deve ser utilizada em conjunto com as outras ferramentas já consagradas para oferecer a melhor opção terapêutica.
Contribuição da Fisioterapia no Tratamento das Alterações Funcionais Decorrentes da Doença Enxerto-Versus-Hospedeiro Crônica Esclerodermoide: uma Revisão de Literatura
Authors: Ferreira Daniele Bittencourt , Luz Laércio Lima , Mattos Inês Echenique
Published: January 2021

A doença-enxerto-hospedeiro crônica esclerodermoide é considerada uma das complicações mais severas em pacientes submetidos ao transplante de células-tronco hematopoiéticas, devido à diminuição da amplitude de movimento articular, resultando em alterações funcionais e limitação na realização de atividades de vida diária. Este estudo teve como objetivo discutir a contribuição da fisioterapia no tratamento de pacientes que apresentam redução da amplitude de movimento decorrente da doença-enxerto-hospedeiro crônica esclerodermoide, com base em revisão da literatura. Trata-se de uma revisão sistemática da literatura, através da busca de artigos publicados entre Janeiro de 2000 e Janeiro de 2010, nas bases de dados Medline, Pubmed, SciELO e Lilacs, utilizando os seguintes descritores: doença enxerto-hospedeiro e amplitude de movimento articular. Foram incluídos artigos que abordavam o tratamento fisioterapêutico na doença enxerto-hospedeiro crônica esclerodermoide. No período selecionado, foram encontrados cinco artigos, mas apenas três preenchiam os critérios de seleção estabelecidos para essa revisão, sendo todos relatos de casos. Os participantes dos estudos apresentavam alterações funcionais semelhantes e se submeteram a tratamento fisioterapêutico, sendo que a maioria evoluiu com melhora funcional e maior independência na realização de atividades de vida diária. Apesar das limitações encontradas nos estudos avaliados, os resultados sugerem que a fisioterapia pode contribuir para a melhora funcional desses pacientes. Desta forma, são necessários outros estudos que utilizem metodologias mais consistentes para que se possa avaliar, de modo mais objetivo, a contribuição da intervenção fisioterapêutica nos pacientes com alterações funcionais decorrentes da doença-enxerto-hospedeiro crônica esclerodermoide.
Definição do conceito de Propriedade Imobiliária na Doutrina e no Sistema Jurídico Constitucional – Cível positivado brasileiro e internacional: Artigo 1.225, Inciso I, da Lei 10.406 de 10 de janeiro de 2002 instituinte do Código Civil Brasileiro
Authors: Costa Josécley Dos Santos
Published: January 2021

O oferecimento deste ofício tem como objetivo definir o conceito da propriedade imobiliária. Traçando um panorama geral evolutivo histórico, desde à pré-história até os dias contemporâneos, referente ao Direito Real, em uma escala global, relacionando as razões históricas, dos sistemas sociais e econômicos ao tocante da propriedade imobiliária, que conduziu o seu aparecimento e desenvolvimento até os conglomerados que instituíram as cidades. Inclusive a criação do seu conceito em caráter nacional e internacional, ordenado por sistemas de governos em seus regimes governamentais, com enfoque interdisciplinar, fornecendo não somente de base, mais também de compreensão dos fatores da indústria da construção civil, motriz do vetor econômico dos vagões das pequenas economias, das propriedades públicas e privadas através do cotidiano, visualizando a trajetória da observação de um pesquisador até o resultado deste trabalho, do qual foi conduzido em uma sequência lógica. A metodologia se pautou na pesquisa bibliográfica, numa abordagem sobre o problema, usando-se dos métodos: indutivo, procedimento histórico, com o da observação da vida real, correspondendo a delimitação do tema, conduzindo para um caminho específico, ou seja, definir o conceito da propriedade imobiliária. Indo das constatações mais particulares, às leis e teorias doutrinárias, numa comunicação ascendente. A indagação e o problema deste trabalho residem na pergunta: o que é a propriedade imobiliária? Vale elucidar, o direito do proprietário e sua faculdade, presente no Código Civil Brasileiro vigente. A origem da propriedade imobiliária na história surge na Idade Antiga, na Idade Média surge a faculdade do proprietário, dentre outros surgimentos, a exemplo: do condomínio, da dicotomia: terras públicas e privadas, da posse, da nomenclatura: Direito Real, etc. Em várias Constituições, Códigos e Legislações Internacionais, não se encontrou a definição deste conceito.
RELATIONS BETWEEN INSTRUCTOR FEEDBACK, SELF-REGULATION, ASSIGNMENT COMPLETION AND ACADEMIC ACHIEVEMENT IN THAI HIGHER LEARNING INSTITUTIONS
Authors: Suamuang Wuttiporn , Easter Matthew A. , Suksakulchai Surachai
Published: January 2021

Purpose â€“ Assignments have been linked with various benefits, including a higher quality of learning and academic achievement. The purpose of this study was to explore the relationship between assignment completion and academic achievement in higher education. Specifically, it investigated the impact of instructor feedback and three constructs of self-regulation (self-efficacy, time management, and help-seeking) on assignment completion (time spent on assignments and number of assignments completed) and academic achievement. Methodology â€“ The study employed a correlational research design and a self-report survey. Data was collected from 1,106 undergraduate students in six universities in Thailand through a convenience sampling approach. Structural equation modelling was used to establish the strength of the relationships among the constructs of the model. Findings â€“ The number of assignments completed was found to have a strong association with academic achievement. Time management was the strongest predictor of the number of assignments completed as well as time spent on assignments. Time management was also the mediator between self-efficacy and the number of assignments completed. However, help-seeking was negatively associated with both the number of assignments completed and academic achievement. Significance â€“ These results have educational implications, and should be helpful for instructors, instructional designers and educators who may use the information to offer undergraduate students appropriate learning tools, strategies and environments for supporting assignment completion and academic achievement.
EXAMINING THE EFFECT OF DIRECTED ACTIVITY RELATED TO TEXTS (DARTs) AND GENDER ON STUDENTSâ€™ ACHIEVEMENT IN QUALITATIVE ANALYSIS IN CHEMISTRY
Authors: Shamsulbahri Mohamad Mahathir , Zulkiply Norehan
Published: January 2021

Purpose â€“ The present study examined the effect of Directed Activity Related to Texts (DARTs) and gender on student achievement in qualitative analysis in chemistry. It focused on the qualitative analysis component of the Chemistry course, which for students has been perceived as being the most difficult aspect of their mastery of the subject. Methodology â€“ The study involved 120 secondary four science stream students from two local fully residential schools. In a quasi-experiment, participants studied the topic of qualitative analysis of salt, using one of the following three instructional methods: Experiment, DARTs, and Combination of Experiment and DARTs. The participants in the three groups were then tested on their knowledge about salt. Findings â€“ Results of a two-way independent ANOVA performed on the experiment data revealed a significant main effect corresponding to the type of instructional method that the three groups were treated to â€” the mean scores for the Combined method group was the highest, followed by the DARTs group, and then the Experiment group. Further analysis using an independent t-test showed that the difference in mean scores between the DARTs and Experiment groups was significant. It is argued that participantsâ€™ learning in the Combined method group might have been enhanced by the DARTs instructional method. The effect of gender and the interaction effect between the variables were not significant. Significance â€“ The findings of the study has provided clear experimental evidence regarding the role of the DARTs instructional method in enhancing qualitative analysis learning in chemistry. These findings also provided important insights to educators on DARTs as an alternative method of teaching and learning the topic on qualitative analysis in chemistry.
ANALISIS POLA PENJUALAN HASIL KOMODITI PADI SAWAH DI DESA RIAS KECAMATAN TOBOALI KABUPATEN BANGKA SELATAN
Authors: Oktia Sela , Setiawan Iwan , Agustina Fournita
Published: January 2021

Penelitian ini bertujuan mendeskripsikan pola penjualan hasil komoditi padi sawah di Desa Rias Kecamatan Toboali Kabupaten Bangka Selatan, menganalisis faktor- faktor yang mempengaruhi keputusan petani dalam memilih pola penjualan hasil komoditi padi sawah dalam bentuk gabah dan beras di Desa Rias Kecamatan Toboali Kabupaten Bangka Selatan, menganalisis perbedaan pendapatan petani yang memilih pola penjualan dalam bentuk gabah dan beras di Desa Rias Kecamatan Toboali Kabupaten Bangka Selatan. Penelitian ini dilaksanakan pada bulan Juni 2019 sampai dengan Januari 2020 di Desa Rias Kecamatan Toboali Kabupaten Bangka Selatan. Metode penelitian yang digunakan adalah metode survei. Metode penarikan contoh yang digunakan adalah sampling insidental dengan sampel dua kelompok petani yang melakukan pola penjualan yang berbeda (gabah dan beras). Jumlah sampel petani yang menjual dalam bentuk gabah sebanyak 35 orang dan jumlah sampel petani yang menjual dalam bentuk beras sebanyak 35 orang. Metode analisis data menggunakan statistik deskriptif, analisis kuantitatif (regresi binary logistik, compare independent samples t-test). Hasil penelitian menunjukkan pola penjualan yang dilakukan petani di Desa Rias yaitu pola penjualan dalam bentuk gabah dan pola penjualan dalam bentuk beras . Variabel yang berpengaruh terhadap keputusan petani dalam memilih pola penjualan gabah dan beras yaitu usia, harga ditingkat produsen dan modal yang dimiliki dengan nilai pada Nalgelkerke R Square sebesar 84,2%.  Terdapat perbedaan pendapatan rata-rata gabah sebesar Rp.4.725.751,43 dan pendapatan petani beras sebesar Rp.13.040.380,00 dengan rentang selisih pendapatan penjualan gabah dan beras yaitu sebesar Rp8.314.629.
Study on Optimum Free-face Condition of Cutting Hard Rock with Tunnel Boring Machine Hob
Authors: Zhang Xuhui , Yashi Liao  , Zhongxiang Chen  , Yimin Xia  , Kui Zhang
Published: January 2021

To explore the rock-breaking characteristics of cutting hard rock under free-face condition by tunnel boring machine (TBM) hob and obtain the optimum free-face condition, the rock-breaking processes such as crack propagation, amount of micro crack and reaction force with penetration depth are first investigated based on discrete element simulation method. Then, the crack length, rock chip area, specific energy consumption etc. with different free-face spacing (S) and free-face height (H) are studied combined with rock-cutting simulation and experiment. The research results show that the formation of the rock chip under free-face condition by TBM hob is driven by tensile failure, and it exists an optimum free-face condition with the S of 80 mm and the H of 200 mm to promote main crack propagation and enhance the rock-cutting efficiency, which can provide a reference for the application of rock-breaking technology under the free-face.
Determinant of Sharia Bank's Financial Performance during the Covid-19 Pandemic
Authors: Ichsan Reza Nurul , Suparmin Sudirman , Yusuf Mohammad , Ismal Rifki , Sitompul Saleh
Published: January 2021

Financial performance as a measuring instrument to know the process of implementing financial resources owned by the company. The Covid-19 pandemic has impacted the banking sector, resulting in poor financing due to debtors' disbursements as a result of the large number of people losing their jobs and difficulties in financing payments. This research aims to analyze the financial performance of Islamic Banks during the Covid-19 pandemic, using records of annual financial statements from 2011 to 2020 through Multiple Linear Regression testing and linearity testing of the model used ramsey test. As a result of this study, the results of the t test found that the Capital Adequacy Ratio (CAR), Operating Costs to Operating Income (BOPO), Financing to Deposit Ratio (FDR) had a positive and significant effect on financial performance (ROA) while Not Performing Financing (NPF) had a negative and insignificant effect on financial performance (ROA). Furthermore, simultaneously capital adequacy ratio (CAR), Operating Costs to Operating Income (BOPO), Financing to Deposit Ratio (FDR) and Not Performing Financing (NPF) significantly influenced the financial performance (ROA) of Sharia banks in Indonesia.
Madrasah Management Model in Langkat District Based on Islamic Spiritual Entrepreneurship
Authors: Sadri Muhammad , Ananda Faisar , Siregar Saparuddin
Published: January 2021

This study aims to identify and know the madrasa management model in Langkat District based on Islamic Spiritual Entrepreneurship. This model will be used as a madrasah management strategy in Langkat District for the continuation of madrasas in the future. This research is descriptive quantitative and explanatory research. The research instrument used was a questionnaire that was accompanied by a brief interview to the research respondents. The data used are primary data and secondary data. Then the data is processed using SEM (Structural Equation Modeling) analysis techniques using AMOS. The study population is all employees implementing or managing madrasa management in Langkat District with a sample of 300 respondents selected according to the SEM analysis standard chosen by accidental sampling technique. The results showed that the management of madrasa based on Islamic values (combined with the values of professionalism) was considered capable of supporting madrasah management and sustainability in the future. There are several factors that support the management of madrasa based on Islamic values, its known honest behavior as the most important factor, the concept of worship to Allah SWT, blessing factor from Allah SWT. But Islamic values (siddiq, amanah, tabligh and fathanah), thankful behavior do not have a significant effect because the measurement is difficult to objectively carry out because it is related to the individual character of a nature that not everyone can or does not want to be measured directly and openly. Therefore it is necessary to have character education, the existence of spirituality education for management managers and optimal management supervision.
Pre-Flood Design Assessment Based on the Needs of the Jambi Community (Case Study of Three Districts / Cities)
Authors: Subandi Andy , Noerjoedianto Dwi , Amir Andy
Published: January 2021

The community's role during a disaster within the first 24 - 72 hours before having government's aid is crucial in making the condition under control in a timely manner, disaster management institution, especially at local level, has not had any models for preparedness training through participative approach based on the local wisdom of Jambi community to reduce disaster risks. The research process is carried out in three stages, (1) the first part is a literature study conducted to obtain information about how to deal with natural disasters, (2) Field studies conducted in several areas related to floods in Jambi Province, (3) ) Analysis Community needs are carried out by reviewing the design of the pre-disaster disaster planning system and the needs of the Flood Preparedness Community in three districts of Jambi province. A sample of 1000 people was divided into 3 groups. Each group will be completed in accordance with the pre-response system and community needs, then analyzed qualitatively. Meanwhile, to find out the management system design. Obtained preparedness data in the three villages with a total subject of 1000 people that 52.33% did not get information about the disaster or disaster preparedness, 64.6% never made an emergency plan for the family when there was a disaster, 68.67% never prepared emergency equipment (food, water, or emergency supplies), 68.27% had not attended disaster preparedness training in the past year, but only 6.2% had never discussed with neighbors about what to do in the event of a disaster. Based on the results of the research, several stages can be planned in the making of the pre-disaster assessment design as an alternative to minimize losses from disasters, which can then be developed as a disaster plan process and making mitigation in accordance with the needs of each district..
Perfil químico da farinha extrusada de sorgo do genótipo BRS 305 por paper spray
Authors: Correia Vinícius Tadeu da Veiga , D'Angelis Danielle Fátima , Macedo Maria Clara Coutinho , Ramos Ana Luiza Coeli Cruz , Vieira Ana Luiza Santos , Queiroz Valéria Aparecida Vieira , Augusti Rodinei , Ferreira Andreza Angélica , Fante Camila Argenta , Melo Júlio Onésio Ferreira
Published: January 2021

O objetivo deste trabalho foi determinar os constituintes químicos da farinha extrusada de sorgo (FES) do genótipo BRS 305 empregando-se a espectrometria de massas com ionização por paper spray (PS/MS), um método que apresenta alta precisão, sensibilidade e possui baixo custo de operação. Foram preparados extratos metanólicos a partir da amostra de farinha extrusada de sorgo e posteriormente avaliados nos modos de ionização positivo e negativo. No modo negativo de ionização foi possível identificar 21 compostos, compreendendo as classes dos flavonoides (48,0%), fenilpropanoides (28,0%), ácidos orgânicos (9,0%), taninos condensados, ácidos graxos e carboidratos (5,0% cada). Adicionalmente no modo de ionização positivo foi possível identificar 9 compostos, pertencentes às classes dos flavonoides (34,0%), carboidratos (22,0%), aminoácidos (22,0%), ácidos graxos e terpenoides (11,0% cada). A espectrometria de massas por paper spray mostrou-se uma técnica eficiente para rápida obtenção de finger prints da amostra de FES avaliada, sendo capaz de identificar um total de trinta compostos químicos, reforçando as propriedades nutricionais e bioativas atribuídas à alguns genótipos de sorgo como o BRS 305.
Unusual treatment for calcifying odontogenic cyst using decompression tube to prevent pathological fracture
Authors: Siqueira Natália Barbosa de , Costa Filho João Roberto Trindade , Rodrigues João Victor Soares , Hochuli-Vieira Eduardo , Okamoto Roberta , Vasconcelos Belmiro Cavalcanti do Egito
Published: January 2021

The calcifying odontogenic cyst (COC) is an uncommon lesion, with variable clinical and histopathological behavior. The cystic form is the most frequent and the most common histological characteristic is the presence of a variable number of phantom cells in the epithelial component. The standard treatment for this injury is enucleation followed by curettage or excision. However, when other factors are associated, this single-step approach can lead to complications such as pathological fractures. A common treatment for keratocysts and dentigerous cysts, but uncommon for COC has been showing high effectiveness. Thus, a two-stage approach using a tubular object to perform initial decompression of the lesion and later excision of the lesion can be performed in order to prevent complications. Here we report a two-stage treatment, through initial surgical decompression, of a COC associated with a lower second molar in the mandibular basilar region, using a tubular device, in which a pathological fracture was prevented. The results of this case corroborate the use of decompression applied to the treatment of COC.
Ozonioterapia como coadjuvante na irrigação do sistema de canais radiculares
Authors: Fernandes Karina Gonzalez Camara , Andreani Dora Inés Kozusny , Tim Carla Roberta , Bazan Lara Gimenez , Moreti Lucieni Cristina Trovati , Simonato Luciana Estevam , Garcia Lívia Assis
Published: January 2021

Na prática clínica da odontologia, é evidenciado que apesar dos avanços na área da endodontia, agentes microbianos e erros técnicos são os principais fatores responsáveis pelo insucesso endodôntico.  O preparo químico mecânico tem como objetivo remover tecido necrosado, vital, microrganismos e seus subprodutos do sistema de canais radiculares. No entanto, este preparo não é suficiente para a limpeza satisfatória em virtude da complexidade anatômica do sistema de canais radiculares, podendo gerar a permanência de microrganismos que poderão continuar viáveis e ativos, interferindo no processo de reparação dos tecidos perirradiculares. Desta forma se faz necessário a busca por soluções químicas irrigadoras ideais que possam proporcionar melhores resultados no tratamento endodôntico. Dentro deste contexto, o objetivo deste estudo é proporcionar, através de uma revisão narrativa, uma compreensão das evidências atuais disponíveis sobre a importância da utilização do ozônio O3, como coadjuvante à irrigação do sistema de canais radiculares na terapia endodôntica. A pesquisa realizada caracteriza-se como exploratório-descritiva, tratando-se da abordagem, consiste em uma pesquisa qualitativa. As buscas foram realizadas nas bases de dados bibliográficas do PubMed/MEDLINE, Biblioteca virtual da saúde (BVS), Web of Science e SciELO. As evidências encontradas nesse estudo direcionam que o ozônio é capaz de inativar microrganismos através da oxidação direta de seus componentes estruturais, podendo ser proposto como um coadjuvante em tratamentos endodônticos contra microrganismos (Gram positivo e Gram negativo) presentes na cavidade oral e canais radiculares. Entretanto, faz-se necessário ensaios clínicos controlados e randomizados para endossar sua eficácia e dosimetrias ideias na prevenção e tratamentos endodônticos.
Toxic effects in Aphanomyces brasiliensis and zebrafish embryos caused by oomyceticides
Authors: Ferreira KdeS , Tachibana L , Colombo DRdaS , Paixão SCOda , Ferreira CM , Badaró-Pedroso C
Published: January 2021

In fish farming, high losses occur during egg incubation and larviculture due to diseases caused by oomycetes. This study aimed to identify the oomycete species that occurs in zebrafishDanio rerioeggs and to evaluate the oomyceticidal effect of copper sulfate, bronopol and methylene blue on the mycelial growth of this organism, as well as to determine the lethal and sublethal toxicity of these compounds in embryos ofD. rerio. The isolates were cultivated in yeast-starch medium to determine the concentration necessary to inhibit mycelial growth by 50% (IC50) and 100% (minimum oomyceticidal concentration) after a 96 h exposure to these compounds. In addition, tests withD. rerioeggs were conducted to determine the lethal concentrations for 50% of the organisms (96h-LC50), and the concentrations that inhibited 17% of the eggs hatching (96h-IC17) after 96 h. The organism responsible for the mortality ofD. rerioeggs was classified by classical and molecular methods asAphanomyces brasiliensis, representing the first report of this pathogen in zebrafish eggs. IC50 values could be determined for both bronopol and copper sulfate, whereas methylene blue had low effectiveness against the oomycete. Copper showed high toxicity toD. rerioeggs at low concentrations, while methylene blue and bronopol toxicity was low and similar to each other. The use of bronopol at a concentration of 4.8 mg l-1for the treatment of zebrafish eggs allows controlling the pathology without causing deleterious effects to the treated organisms.
Amphibian chytrid infections along the highest elevational gradient of the Brazilian Atlantic Forest
Authors: Zornosa-Torres C , Lambertini C , Toledo LF
Published: January 2021

Environmental variation along elevational gradients shapes conditions for pathogen development, which influences disease outcomes. Chytridiomycosis is a non-vectored disease caused by the aquatic fungus Batrachochytrium dendrobatidis (Bd) and is responsible for massive declines of amphibian populations all over the world. Several biotic and abiotic factors are known to influence Bd infection dynamics in amphibians, including temperature and host species richness. Here, we quantified Bd prevalence and load along an elevational gradient in the Caparaó National Park (CNP), Brazil, and tested for associations of Bd infections with elevation, temperature, and species richness. We hypothesized that Bd infections would increase as local species richness decreased with elevation. We detected Bd along the entire elevational gradient and found a negative association between infection load and elevation. We did not detect significant associations between infection prevalence and elevation. Our findings are consistent with other wide elevational gradient studies, but are contrary to 2 other studies performed in the Atlantic Forest. We did not find the minimum elevational range that should be sampled to detect the influence of elevation on Bd variation. Our study represents the widest elevational gradient that has been sampled in Brazil and contributes to a better understanding of Bd distribution and dynamics in natural systems.
MYANMAR1962: FEMINISM IN THE POST MILITARY JUNTA ERA
Authors: Sari Artha Karyn , Fadlilah Afifatul , Romadhona Olvira , Nakajima Riko
Published: January 2021

Aung San Suu Kyi is a feminist activist who opposes the Military Junta government.  She highly upholds gender equality and strives for all people to have the right to live.  However, she ended up in prison for years because of his bold actions. After being released from the detention center, Aung San Suu Kyi campaigned on Feminism, which has influenced many women to fight for their rights.  Because of Aung San Suu Kyi, more and more women, both students, workers, and business people, also voiced their goals, especially women's participation in various sectors and women's freedom in leading the country.  The participation of women they strive for participates in the media, public administration, politics, and the student movement. This movement was implementing because women can also contribute to advancing the country's economy and politics. The U.N role is also very influential in this case through its campaigns that include men to voice gender equality.  Because gender equality is not only for women, but everyone has the right to gender equality. Due to, to achieve the same goal, namely peace between humans
Collagen Synthesis, Nitric Oxide and Asymmetric Dimethylarginine
in Diabetic Subjects Undergoing Hyperbaric Oxygen Therapy
Authors: Gurdol F , Cimsit M , Oner-Iyidogan Y , Kocak H , Sengun S , Yalcinkaya-Demirsoz S
Published: January 2021

The main pathological condition in patients with impaired wound
healing is diabetes mellitus. These patients have significantly low
circulating nitric oxide (NO) levels because the stimulatory action
of insulin on NO synthesis is absent. Additionally, asymmetric
dimethylarginine (ADMA), an inhibitor of NO synthase, is
increased owing to the generation of oxidative stress. NO was
thought to contribute to wound healing. Hyperbaric oxygen
(HBO) treatment is generally used in order to accelerate the
healing of wounds. The aim of this study was to determine the
changes in plasma procollagen type I and III N-terminal peptides
(PINP and PIIINP), total nitrite/nitrate (NOx) and ADMA levels;
and to evaluate their relation to healing during the HBO
treatment of foot ulcers. Data obtained from 18 diabetic patients
before and after the HBO therapy were compared statistically by
the Wilcoxon test. NOx was increased in 11 and ADMA was
decreased in 12 patients following HBO treatment. Both PINP
(32.6±29.4 μg/l vs 44.3±33.4 μg/l) and PIIINP (6.97±3.01 μg/l
vs 7.92±2.49 μg/l) were significantly increased (p<0.05).
Progressive reductions were observed in wound areas, as
assessed by the digital wound imaging. In 12 patients, wounds
healed by 50 % or higher; whereas only two subjects had
minimal improvements (15 % or less healing). The duration of
diabetes correlated negatively with wound healing (r = -498,
p<0.05). This study suggests that increased collagen synthesis is
associated with wound healing during hyperbaric oxygen therapy.
Nitric oxide generation may also contribute to the healing
process.
Levels of Circulating Biomarkers at Rest and after Exercise
in Coronary Artery Disease Patients
Authors: Danzig V , Míková B , Kuchynka P , Benáková H , Zima T , Kittnar O , Škrha J , Linhart A , Kalousová M
Published: January 2021

As traditional risk factors are unable to fully explain the
pathogenesis of coronary artery disease (CAD), novel
mechanisms became a target of many investigations. Our aim
was to study the response of selected markers to physical
exercise. High-sensitive C-reactive protein (hs-CRP), matrix
metalloproteinases 2 and 9 (MMP-2, MMP-9), advanced oxidation
protein products (AOPP), soluble receptor for advanced glycation
end-products (sRAGE), pregnancy-associated plasma protein A
(PAPP-A), E-selectin, vascular endothelial growth factor (VEGF)
and B-type natriuretic peptide (BNP) levels were measured in
serum of 21 CAD patients and in 22 healthy controls at rest and
after exercise bicycle stress test performed up to the maximal
tolerated effort. At rest, hs-CRP, AOPP, MMP-9 and BNP were
significantly elevated in the CAD patients as compared with
controls. In contrast, P-selectin was significantly lower in CAD
patients and a tendency to lower levels of sRAGE was noted.
After exercise MMP-9 and BNP, increased significantly in both
groups. In conclusions, CAD patients have elevated hs-CRP,
AOPP, MMP-9 and BNP - novel markers related to cardiovascular
risk or left ventricular overload. MMP-9 and BNP increase
significantly with exercise in both healthy individuals and CAD
patients.
Remifentanil Protects Myocardium through Activation of AntiApoptotic Pathways of Survival in Ischemia-Reperfused Rat Heart
Authors: Kim H S , Cho J E , Hong S W , Kim S O , Shim J K , Kwak Y L
Published: January 2021

Remifentanil is a commonly used opioid in anesthesia with
cardioprotective effect in ischemia-reperfused (I/R) heart. We
evaluated the influence of remifentanil on myocardial infarct size
and expressions of proteins involved in apoptosis in I/R rat heart
following various time protocols of remifentanil administration.
Artificially ventilated anesthetized Sprague-Dawley rats were
subjected to a 30 min of left anterior descending coronary artery
occlusion followed by 2 h of reperfusion. Rats were randomly
assigned to one of five groups; Sham, I/R only, remifentanil
preconditioning, postconditioning and continuous infusion group.
Myocardial infarct size, the phosphorylation of ERK1/2, Bcl2, Bax
and cytochrome c and the expression of genes influencing Ca2+
homeostasis were assessed. In remifentanil-administered rat
hearts, regardless of the timing and duration of administration,
infarct size was consistently reduced compared to I/R only rats.
Remifentanil improved expression of ERK 1/2 and anti-apoptotic
protein Bcl2, and expression of sarcoplasmic reticulum genes
which were significantly reduced in the I/R rats only.
Remifentanil reduced expression of pro-apoptotic protein, Bax
and cytochrome c. These suggested that remifentanil produced
cardioprotective effect by preserving the expression of proteins
involved in anti-apoptotic pathways, and the expression of
sarcoplasmic reticulum genes in I/R rat heart, regardless of the
timing of administration.
[3H]SCH 23390 binding in various brain regions of C57BL/6J mice with repeated experience of victory or social defeat in agonistic interactions
Authors: Avgustinovich D F , Alekseyenko O V
Published: January 2021

The binding of [3H]SCH 23390 has been studied in various brain
regions of male mice with the experience of repeated victory
(winners) or defeat (losers) gained over 10 (T10) and 20 (T20)
days of daily agonistic confrontations. In the frontal cortex, Bmax
of [3H]SCH 23390 binding sites was found to be increased in T10
losers and decreased in T20 losers when compared to the control
mice. In the striatum, T10 and T20 winners had reduced values
of [3H]SCH 23390 binding sites than the ones in the control mice.
The Kd was increased in the frontal cortex of T10 losers and T10
winners as well as in the amygdala of T20 losers. Reduced Kd
values were found in the striatum of all experimental groups as
well as in the amygdala of T20 winners. Thus, both specific
changes relating to social behavior patterns and non-specific
ones in [3H]SCH 23390 binding were found in the brain regions
of mice after 10 and 20 days of intermale confrontations.
The Effects of Short-Term Norepinephrine Up-Titration
on Hemodynamics in Cardiogenic Shock
Authors: Rokyta R , Tesařová J , Pechman V , Gajdoš P , Kroužecký A
Published: January 2021

A higher mean arterial pressure (MAP) achieved by
norepinephrine up-titration may improve organ blood flow in
critically ill, whereas norepinephrine-induced afterload rise might
worsen myocardial function. Our aim was to assess the effects of
norepinephrine dose titration on global hemodynamics in
cardiogenic shock. We prospectively evaluated 12 mechanically
ventilated euvolemic patients (aged 67±12 years) in cardiogenic
shock (10 patients acute myocardial infarction, 1 patient dilated
cardiomyopathy, 1 patient decompensated aortic stenosis).
Hemodynamic monitoring included arterial and Swan-Ganz
catheters. The first data were obtained at MAP of 65 mm Hg,
then the norepinephrine dose was increased over 40 min to
achieve MAP of 85 mm Hg. Finally, the norepinephrine-dose was
tapered over 40 min to achieve MAP of 65 mm Hg.
Norepinephrine up-titration increased MAP to the predefined
values in all patients with concomitant mild increase in filling
pressures and heart rate. Systemic vascular resistance increased,
whereas cardiac output remained unchanged. During
norepinephrine down-titration, all hemodynamic parameters
returned to baseline values. We observed no changes in lactate
levels and mixed venous oxygen saturation. Our data suggest
that short-term norepinephrine dose up-titration in cardiogenic
shock patients treated or pretreated with inotropes was tolerated
well by the diseased heart.
UPAYA MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH SISWA MELALUI MODEL PEMBELAJARAN INQUIRY
Authors: Br Harianja Nurmauli
Published: January 2021

This study aims to improve students' ability in problem solving, for that we need learning that can accommodate the stages in achieving learning objectives in the form of drawing conclusions through hypotheses and data collection, the right learning model, one of which is the inquiry learning model. This research was conducted in class VI B SDN 9 Mandau. The research was carried out from March to April 2019. . The research instrument used the observation sheet of students' problem solving abilities. The results showed that the problem solving ability of students in the first cycle was 73.37 with the total classical completeness of 62.96% where only 17 students reached the KKM. In cycle II the students' problem solving ability reached 81.01 with a total classical completeness of 92.59% where 25 students reached the predetermined KKM. Based on the results of the study, it can be concluded that the inquiry learning model can improve the problem solving abilities of the VI B grade students of SDN 9 Mandau.