bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical methods for the multiplicative partial differential equations
Authors: Yazıcı Muhammet , Selvitopi Harun
Published: November 2017

We propose the multiplicative explicit Euler, multiplicative implicit Euler, and multiplicative Crank-Nicolson algorithms for the numerical solutions of the multiplicative partial differential equation. We also consider the truncation error estimation for the numerical methods. The stability of the algorithms is analyzed by using the matrix form. The result reveals that the proposed numerical methods are effective and convenient.
Modulation of Ether-à-Go-Go Related Gene (ERG) Current Governs Intrinsic Persistent Activity in Rodent Neocortical Pyramidal Cells
Authors: Cui Edward D. , Strowbridge Ben W.
Published: November 2017

While cholinergic receptor activation has long been known to dramatically enhance the excitability of cortical neurons, the cellular mechanisms responsible for this effect are not well understood. We used intracellular recordings in rat (both sexes) neocortical brain slices to assess the ionic mechanisms supporting persistent firing modes triggered by depolarizing stimuli following cholinergic receptor activation. We found multiple lines of evidence suggesting that a component of the underlying hyperexcitability associated with persistent firing reflects a reduction in the standing (leak) K+current mediated by Ether-a-go-go-Related Gene (ERG) channels. Three chemically diverse ERG channel blockers (terfenadine, ErgToxin-1, and E-4031) abolished persistent firing and the underlying increase in input resistance in deep pyramidal cells in temporal and prefrontal association neocortex. Calcium accumulation during triggering stimuli appears to attenuate ERG currents, leading to membrane potential depolarization and increased input resistance, two critical elements generating persistent firing. Our results also suggest that ERG current normally governs cortical neuron responses to depolarizing stimuli by opposing prolonged discharges and by enhancing the poststimulus repolarization. The broad expression of ERG channels and the ability of ERG blocks to abolish persistent firing evoked by both synaptic and intracellular step stimuli suggest that modulation of ERG channels may underlie many forms of persistent activity observedin vivo.

SIGNIFICANCE STATEMENTPersistent activity, where spiking continues beyond the triggering stimulus, is a common phenomenon observed in many types of neurons. Identifying the mechanism underlying this elementary process of memory is a step forward in understanding higher cognitive function including short-term memory. Our results suggest that a reduction in the currents normally mediated by Ether-a-go-go-Related Gene (ERG) K+channels contributes to persistent firing in neocortical pyramidal cells. ERG currents have been previously studied primarily in the heart; relatively little is known about ERG function in the brain, although mutations in ERG channels have recently been linked to schizophrenia. The present study is among the first to describe its role in neocortex in relation to biophysical correlates of memory function.
RelationCRIPs with Dramaturgy: The Intervention of the Dramaturge in Devised CRIP Theatre
Authors: Chrystian Tonya Rae
Published: November 2017

Disability theatre has a complex Canadian history according to disability studies scholar Kirsty Johnson, and “Canadian artists with disabilities have found many and provocative ways to ‘get on stage’” (Johnson 4). The formation of disability art and theatre is as multifaceted and diverse as disability itself, but there will always remain a part of the process that must confront the ableism and exclusion perpetuated by the social models of oppression both on and offstage.  As disability theatre seeks to challenge dominant narratives, relocate the status of the disabled body, and positively re-imagine the value of disability, one of the important components is the role that dramaturgy can play in the formation of disability theatre, particularly in the case of devised CRIP theatre. This paper will explore some of the interventions and approaches dramaturgy may subsume to support the creation of experiential theatre that expresses the lives and narratives of disabled and mixed communities. The arguments explored in this paper will be supplemented with material taken from the collaborative production of Love in the Margins that was part of the 2016 Chinook Series in Edmonton, Alberta, becoming the first professional presentation of disability theatre in Edmonton.  This paper will also explore topics such as the role of playwriting and dramaturgy in devised, experiential, and social-justice theatre, how the word “professional” can be inclusively re-defined, and the problems, processes, and ethical questions of journeying from devised community theatre to professional theatre.
Review of Diedrich, L. (2017), "Indirect Action: Schizophrenia, Epilepsy, AIDS and the Course of Health Activism"
Authors: Day Ally
Published: November 2017

In her recent monograph, Indirect Action: Schizophrenia, Epilepsy, AIDS and the Course of Health Activism, Lisa Diedrich has undertaken the project of expanding/re-vising/exploding our current narrative of the AIDS epidemic for the purpose of expanding what we think of as activism.
Review of Hill Collins, P., & Bilge, S. (2016), "Intersectionality"
Authors: Jones Chelsea
Published: November 2017

Ready or not: intersectionality is sweeping across classrooms in largely student-led strokes. Luckily, Patricia Hill Collins and Sirma Bilge, women who’ve penned texts to the tune of critical inquiry and praxis for years, remind us what intersectionality means and how it emerges in their latest collaboration, Intersectionality. Their book highlights concerns with intersectionality’s institutionalization while simultaneously arguing that many colleges and universities have missed opportunities to connect with the ways students live intersectionally (through jobs, sports, care-roles, and so on) (47). Urging readers away from insincere “diversity” and “cultural competence” claims, they explain that readers with vested interested in education work in contexts where “some forms of diversity remain more desirable than others” and that taking intersectionality seriously means engaging in critical, collaborative, coalition-building work “with people who really are different” (174, 169).
Norwegian bare singulars revisited
Authors: Rosén Victoria , Borthen Kaja
Published: November 2017

Borthen (2003) analyzed bare singulars in Norwegian. In this paper some of the claims made there are reexamined by searching in NorGramBank. The study provides new empirical to support to some of the claims put forth in the earlier work, but it also reveals problems with the prior analysis.
Microcirculatory parameters in compensated and decompensated type 2 diabetes mellitus
Authors: Suchkova O V , Gurfinkel Yu I , Sasonko M L
Published: November 2017

Aim. To reveal the features of microcirculatory parameters in compensated and decompensated type 2 diabetes mellitus (T2DM). Subjects and methods. A total of 196 patients with T2DM were examined and divided into 2 groups: 1) 52 patients (40.4% of men) aged 52.8±8.7 years with compensated T2DM (glycated hemoglobin (HbA1с), 6.3±0.5%); 2) 68 patients (38.2% of men) aged 52.8±8.1 years with decompensated T2DM (HbA1с, 9.4±1.7%). Both patient groups had concomitant hypertension (its prevalence, degree, stage of hypertension were comparable). A control group consisted of 76 volunteers (40.8% of men) aged 52.2±8.7 years with normal carbohydrate metabolism and without signs of cardiovascular disease (HbA1с, 5.3±0.49%). Capillary blood flow in the finger nail-fold area was investigated in all the participants. A digital optical capillaroscope with image-processing software was used to obtain quantitative blood microcirculatory parameters. The diameters of arterial and venous capillary segments were measured, by calculating the remodeling rate. The degree of capillary tortuosity, network density, and polymorphism and the size of the perivascular zone (PZ) were estimated. Blood rheological properties and capillary blood flow velocity were also investigated. Results. The decompensated T2DM group compared to the compensated T2DM group was found to have a narrowing of the arterial capillary segment diameter (8.4±2.0 µm; p=0.009) and an increase in remodeling rates (1.47±0.22; p=0.000). The tendency of the PZ size to be larger in patients with decompensated T2DM compared to those with compensated T2DM (p=0.080) and the increase in this indicator compared to the control group (p=0.001) reflect the presence of edema syndrome in Group 2, as laboratory confirmed by a statistically significantly elevated sodium level (p=0.000; p=0.006). The enlarged venous capillary segment demonstrates involvement of the venous component in microcirculatory disorders in T2DM. The reduction in the density of the capillary network and the increase in capillary tortuosity and polymorphism, which were also observed in the patients of both groups versus the control group, are referred to as disorders that are characteristic of T2DM. Conclusion. In decompensated T2DM, capillary bed structural and functional changes are found as a narrowing of the arterial capillary segment, an increase in the rate of remodeling, and enlargement of the PZ. Digital capillaroscopy opens up new possibilities for assessing the magnitude of changes in the microcirculatory system in DM and can simultaneously evaluate the efficiency of treatment, by monitoring the status of the microvasculature.
Shereshevsky-Turner syndrome: Estrogen replacement therapy and cardiovascular risk factors
Authors: Yevstigneeva O A , Andreeva E N , Grigoryan O R , Volevodz N N , Melnichenko G A , Dedov I I
Published: November 2017

Aim. To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT. Subjects and methods. From 2010 to 2012, a total of 41 patients aged 14 to 35 years with STS were examined in the framework of a prospective observational study. 100 STS case histories in 2000 to 2009 were retrospectively analyzed. The indicators of the so-called cardiometabolic risk, such as body mass index (BMI), lipidogram readings, venous plasma glucose levels, and blood pressure, were estimated in relation to the type of MHT. In the prospective part of the investigation, an angioscan was used to estimate vessel characteristics (stiffness, wall tone, endothelial function (EF)), by using the examination data. Results. 90% of the patients with STS were found to have risk factors for CVEs: atherogenic dyslipidemia (85%; 51% in the general female population of the same age), diastolic hypertension (36%; no more than 5% that is not typical for age-matched healthy general female population). In addition to increased arterial wall stiffness (AWS), obvious EF disorder is typical for STS patients. MHT was accompanied by a dose-dependent (estradiol, at least 2 mg) reduction in diastolic blood pressure by an average of 13% over 24 months, an increase in high density lipoprotein levels by more than 10% over 24 months and also contributedto a decrease in AWS and an improvement in EF. Conclusion: By favorably affecting the EF of vessels and reducing the severity of atherogenic dyslipidemia, MHT potentially enables a reduction in CV risk in patients with STS.
Associations between metabolic syndrome and reduced lung function in young people
Authors: Kovalkova N A , Ragino Yu I , Travnikova N Yu , Denisova D V , Shcherbakova L V , Voevoda M I
Published: November 2017

Aim. To reveal possible associations between metabolic syndrome (MS) and reduced lung function. Subjects and methods. In 2013—016, a cross-sectional survey was conducted in 908 Novosibirsk dwellers, which included spirometry to evaluate external respiratory function (ERF). For the detection of MS, the investigators used the 2009 All-Russian Research Society of Cardiologists criteria: waist circumference (WC) > 80 cm for women and >94 cm for men in combination with two of the following criteria: blood pressure (BP) ≥130/85 mm Hg, triglycerides (TG) ≥1.7 mmol/l, high-density lipoproteins (HDL) cholesterol
Progressive pulmonary hypertension in a patient with type 1 Gaucher disease
Authors: Ponomarev R V , Model S V , Averbukh O M , Gavrilov A M , Galstyan G M , Lukina E A
Published: November 2017

Gaucher disease is the most common form of hereditary enzymopathies combined into a group of lysosomal storage diseases. The basis for the disease is a hereditary deficiency of the activity of acid β-glucosidase, a lysosomal enzyme involved in the catabolism of lipids, which results in the accumulation of nonutilized cellular metabolism products in the macrophage lysosomes. The main clinical manifestations of type 1 Gaucher disease are cytopenia, hepatomegaly, and splenomegaly, and bone lesion. One of the atypical clinical manifestations of Gaucher disease is damage to the lungs with the development of pulmonary hypertension, which is usually considered within the underlying disease — the development of pneumosclerosis due to macrophage dysfunction. The paper describes a case of progressive pulmonary hypertension in a patient with type 1 Gaucher disease.
Endothelial dysfunction and arterial wall stiffness: New targets in diabetic nephropathy
Authors: Murkamilov I T , Sabirov I S , Fomin V V , Yusupov F A
Published: November 2017

In recent years, one of the promising areas in clinical medicine is the study of impaired ments in endothelial function and arterial wall stiffness, which can be referred to as one of the important predictors of cardiovascular events in patients with chronic kidney disease, including that of diabetic etiology. There is strong evidence that endothelial function and great artery stiffness may be used as reliable clinical and instrumental indicators to evaluate the efficiency of therapeutic measures and the rate of progression of cardiovascular disorders in type 2 diabetes mellitus. The article presents data on the role of endothelial dysfunction and arterial wall stiffness in the progression of chronic kidney disease in type 2 diabetes mellitus and discusses the possibility of their correction with pharmacological agents.
Plate Reader experiment v1
Authors: Behle Anna
Published: November 2017

This protocol covers the inoculation, cultivation, IPTG-induction and plate reader measurement of E. coli BL21 strains carrying constructs with various toehold switch devices from Green et al., 2014.
HBV genotyping of S and C genes. v1
Authors: Bivigou-Mboumba Berthold , Amougou-Atsamac Marie , Njouomc Richard , François-Souquière Sandrine
Published: November 2017

HBV genotyping was performed by sequencing and phylogenetic analyses of the surface (S) and core (C) fragments. Briefly, HBV DNA was first extracted from 400 µL of plasma and eluted in 100 µL of pure water, using the QIAamp Viral DNA Mini Kit (QIAGEN, Courtaboeuf, France) followed by semi-nested PCR amplification of the S (930 bp) and C (1010 bp) gene fragments using MP Taq Core Kits 25 (MP Biomedical Diagnostic, Europe). The S fragment amplification was performed as described elsewhere. (Hu X, et al., 2000 [PMID:10677515] ; Makuwa M et al., 2006 [PMID: 16847965]; Olinger CM et al.,2006 [PMID: 16603517]) The first round was performed using primers sets 58P (5’-CCT GCT GGT GGC TCC AGT TC-3’) and 979 (5’-ATT GGA AAG TAT GTC AAA GAA TTG TGG GTC TTT TG-3’). The 50 µL final reaction mixture contained 31.4 µL of RNase DNase Free water, 5 µL of buffer 10X with MgCl2 (25 mM), 0.4 µL of dNTPs (25 mM), 1.5 µL of each primer (10 µM), 0.2 µL of Taq polymerase (5 U/µL) and 10 µL of extracted DNA. The second round PCR used the 58P/Mc2r (5’-TGGAAGTTGGGGATCATTGCC-3’) primer on a 50 µL final reaction mixture containing 36.4 µL of RNase DNase Free water, 5 µL of buffer 10X with MgCl2 (25 mM), 0.4 µL of dNTPs (25 mM), 1.5 µL of each primer (10 µM), 0.2 µL of Taq polymerase (5 U/µL), and 5 µL of first round PCR product. The PCR program was the same for the first and second round PCRs including denaturation at 94°C for 5 min followed by 40 cycles of denaturation at 94°C for 1 min, annealing at 55°C for 30 s and elongation at 72°C for 1 min, followed by final elongation at 72°C for 5 min. For the C fragment amplification, the couplet of primers BCP1F (5’-GCA TGG AGA CCA CCG TGA AC-3’) / 2853N (5’-TCA CCA TAT TCT TGG GAA CA-3’) was used for the first round and the couplet BCP2F(5’-CAT AAG AGG ACT CTT GGA CT-3’) / 2853N for the second round. The amplification conditions were the same as for the S fragment. The PCR products were purified using QIAquick PCR Purification Kit (Qiagen, Courtaboeuf, France) and submitted for sequencing at Macrogen Inc (Meibergdreef, Netherlands).
Klassifikation des Arbeitsfortschritts
Authors: Niedersteiner Sascha , Lang Jonas , Pohlt Clemens , Schlegl Thomas
Published: November 2017

Steigende Anforderungen an die Qualität von zum Teil manuell gefertigten Produkten führen dazu, dass Handarbeitsplätze mit Assistenzsystemen für die Unterstützung der am Arbeitsplatz arbeitenden Mitarbeiterinnen und Mitarbeiter ausgestattet werden. Der Beitrag beschreibt einen neuen Ansatz, um mittels Verfahren des maschinellen Lernens die Objekterkennung sowie die Transitionen eines, den Arbeitsprozess repräsentierenden Zustandsautomaten eines solchen Systems einzulernen. Hierfür werden nach einer Vorverarbeitung Daten aus einer Tiefenkamera in drei Stufen durch Support Vector Machines (SVM) klassifiziert und das Ergebnis mit dem Zustandsautomaten verknüpft. Das Konzept wird an einem industriellen Montageprozess überschaubarer Komplexität evaluiert; es zeigt gute Ergebnisse hinsichtlich der Robustheit gegenüber Fehlern bei der Objektklassifikation.
ECONOMIC INTEGRATION OF UKRAINE WITH THE EU IN TECHNICAL STANDARDS REGULATION AREA
Authors: Shnyrkov O.
Published: November 2017

The structural reforms in Ukraine are taking place under extraordinary and unprecedented for international economy circumstances. The annexation of Crimea, the war in Donbas region, the loss of important economical potential, human causalities, lack of territorial integrity guaranties from other countries formed a new system of challenges not only for our country but for the whole world in total. Under the external aggression and trade war with Russia the Association Agreement with the European Union should become the main and effective Ukraine’s economical structural changes mechanism. The economical part of Association Agreement with the EU and the deep free trade agreement are characterized as liberalization of mutual trade and regulatory convergence especially including the technical standards regulation field. Modern liberalization in mutual trade between Ukraine and EU has low tariff protection of the EU market for Ukrainian goods and doesn’t not affect the common volume of trade. That is why the technical barriers remains the main obstacles in Ukrainian goods export to the European single market.
THE CONCEPT OF GENOCIDE IN INTERNATIONAL LOW
Authors: Holovchenko V.
Published: November 2017

The article spotlights genesis and essence of genocide concept, nature of contemporary genocide tragedies based on historical and philosophical, chronological and comparative analysis methods, and founds theirs compliance with international legal definition of genocide’s term in the context of not avoiding criminal responsibility for crimes against humanity. It was affirmed that even for the unsteady post-bipolar era roots of tragedies of genocide remains an idea of the nature or historically formed social inequality of ethnic, racial, religious, cultural, linguistic, territorial, social class and other groups and communities, and the desire to increase vital natural or a public resource of one community (group) at the expense of another. It is recognized that term “genocide” is not immediately received wide recognition and was initially not quite identical to the concept of “crimes against humanity”. Generally speaking, lawyers and politicians for some time came out that genocide – only one of the possible crimes against humanity. Therefore, the tragedy of the Armenian people 1915-16 still classified in the world as a crime against humanity. Genocide always aims at complete or partial destruction of a national, ethnic, racial or religious group.
К вопросу о рациональной системе показателей состояния и развития научной сферы
Authors: Башина Ольга Эмильевна , Николенко Владимир Николаевич
Published: November 2017

В статье рассматривается действующая система показателей состояния науки, критикуются отдельные ее положения. Рассматриваются показатели, которые должны более объективно и в большем соответствии с природой научного знания отражать состояние научной сферы.

 
О теоретико-методологических основаниях биосоциологии
Authors: Юдин Борис Григорьевич
Published: November 2017

Статья составлена из ответов выдающегося российского философа и всемирно признанного специалиста по биоэтике Бориса Григорьевича Юдина (1945–2017) на вопросы Вал. А. Лукова в связи с формированием нового научного направления «биосоциология молодежи». Ответы содержатся в частном письме, которое Б. Г. Юдин направил 29.07.2013 г. В полном объеме публикуются впервые.

 
Técnicas de restauración de suelos basadas en el uso de residuos orgánicos: seis años de beneficios sobre las propiedades de un suelo forestal
Authors: Hueso-González P. , Martínez-Murillo J.M. , Ruiz-Sinoga J.D.
Published: November 2017

Restaurar la vegetación nativa es una de las maneras más efectivas de recuperar la calidad de los suelos forestales. Después de la repoblación, durante el enraizamiento del plantón, los beneficios de la vegetación sobre el suelo aún no se manifiestan y los suelos siguen siendo altamente vulnerables a la erosión y pérdida de carbono orgánico. Los procesos de degradación podrían minimizarse mediante la implementación de enmiendas orgánicas. El objetivo es analizar los beneficios del uso de diferentes enmiendas orgánicas sobre algunas propiedades del suelo. Los tratamientos seleccionados fueron: (i) suelos reforestados y enmendados con un acolchado de restos de paja; (ii) suelos reforestados y enmendados con un acolchados de astillas de pino carrasco (Pinus halepensis Mill.); (iii) suelos reforestados y enmendados con lodos de depuradora; (iv) suelos reforestados y enmendados con estiércol de origen vacuno y; (v) no enmendados. Todas las enmiendas se aplicaron a dosis de 10 Mg ha-1. Seis años después de su aplicación, únicamente la adición de enmiendas orgánicas, tipo acolchado de paja o poda, han supuesto un incremento significativo de los valores de carbono orgánico del suelo respecto a la reforestación bajo condiciones de suelo desnudo. Este aumento estaba directamente relacionado el aumento de la actividad microbiológica que favorece el incremento de la estabilidad media de los agregados. Los tratamientos con lodos de depuradora o estiércol de origen vacuno, no serían métodos útiles para la mejora de la calidad del suelo.
Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa
Authors: Kerkar Shantadurga S. , Bhandare Padma N.
Published: November 2017

Background: CVDs have emerged as a leading cause of mortality and morbidity in the world as well as in India. Drug usage is life saving and at times many drugs may be needed. Drug utilization studies aid to find the appropriateness of treatment, identify shortcomings if any, and provide a feedback to the healthcare providers to improve their management with drugs. So such types of studies are of vital importance in every hospital.

Methods: This was a prospective, observational study of 180 patients with CVDs admitted in medicine and cardiology wards of a tertiary care hospital, conducted through case records and patients’ interviews. Data was represented as mean±SD, number and frequency.  

Results: Incidence of cardiovascular diseases was more in males (56.67%) than the females (43.33%). Average number of drugs prescribed per patient was 9.16 and that of cardiovascular drugs was 5.08 ± 2.15. Antiplatelets (88.88%) were the most commonly prescribed cardiovascular drugs followed by hypolipidemics (82.22%). About 15.06% of injectables and 1.2% of fixed dose combinations (FDCs) were prescribed. Drugs prescribed by generic names were 1.6% and those from the National List of Essential Medicines were 92.79%.

Conclusions: The results of this study suggested: polypharmacy, overuse of injections and low prescribing habits from essential drug list. Though antiplatelet, hypolipidemic use was higher, these are an essential part of treatment of certain CVDs. 
Papillary mucous cystadenoma of parotid gland
Authors: Anuradha Ananthaneni , Suresh Babu Undavalli , Vignatha Penumala , Bhavana Bagalad S.
Published: November 2017

Cystadenomas are rare benign salivary gland tumours characterised by prominent epithelium-lined papillary projections into the cystic spaces. Cystadenoma accounts for 2% of all salivary gland tumors, occurring most commonly in major salivary glands. Histopathologically there are two variants, papillary and mucinous variant. However very few cases are being reported in literature. We report a case of papillary cystadenoma occuring in parotid gland in a 28 year old male patient. Clinically, it presents as a soft, fluctuant, sessile and non-tender swelling measuring about 4×3.5 cm in diameter. Excisional biopsy was performed. The histopathological features were characteristic of papillary cystadenoma. This article highlights its clinical and histopathological features along with review of literature. 
Assessing disease severity by hsCRP as a biochemical marker for psoriasis
Authors: Jain Kriti , Krishna Arvind , Rathore B. S.
Published: November 2017

Background: For a complex chronic disease like psoriasis, having a biomarker to objectively assess the clinical severity can be very helpful in disease management.

Methods: In a hospital based prospective study, 70 patients of psoriasis diagnosed clinically, were studied. The extent of disease severity was assessed using PASI and BSA and patients were grouped into having mild, moderate and severe disease using these scores. Serum high sensitivity C-reactive protein (hsCRP) levels were then estimated for each group.

Results: Of the 70 psoriasis cases enrolled, 46 patients were male and 24 females. Patients with early onset psoriasis were associated with higher values of hsCRP than those with late onset (r=-0.063; p=0.012). A positive correlation was seen between the PASI score and hsCRP levels (r=0.891; p≤0.001). On comparing mean PASI and mean hsCRP in severity groups (mild, moderate and severe), hsCRP was higher in the group with maximum severity (p≤0.001).

Conclusions: A negative correlation between the age of onset and hsCRP implies that, earlier the age of onset, higher is the value of hsCRP. Our study shows a positive correlation between the body surface area and PASI score both of which varied linearly with hsCRP values. The findings also suggest that patients with severe psoriasis have higher mean serum hsCRP levels than patients with mild psoriasiss.We proposed hsCRP as a useful marker of psoriasis severity that could be used to monitor psoriasis and, together with PASI, as a global index of disease severity.

 
PENGARUH SPONSORSHIP DALAM MENINGKATKAN BRAND AWARENESS (Studi pada Sponsorship Garuda Indonesia Terhadap Liverpool FC sebagai Global Official Airline Partner)
Authors: Salma Aqidah Nuril
Published: November 2017

Garuda Indonesia is the first and the only airline in Indonesia that implement sponsorship programs with international soccer club, Liverpool FC. This study uses sponsorship dimension consisting of target audience reach, compatibility with the company’s or brand positioning, and message capacity. This research applies quantitative approach and involves 83 respondents as samples collected by non-probability and snowball sampling techniques. The results suggest that sponsorship has a strong effects towards brand awareness. Futher, multiple regression analysis also indicates that the dimensions of sponsorship compatibility with the company’s or brand positioning have the biggest influence towards brand awareness than the other two dimensions.
Beyond the “Haves and Have Nots”: Using an Interdisciplinary Approach to Inform Federal Data Collection Efforts with Indigenous Populations
Authors: Lee C. Aujean
Published: November 2017

This study demonstrates how multiple methods can inform national survey data collection efforts for Indigenous populations using Pacific Islanders as a case study. National data surveys are oftentimes limited in how they collect data on small populations due to data suppression, and they lack nuance in how they aggregate distinct populations. I conduct linear regression models of U.S. Census data to demonstrate that Pacific Islanders lag behind Whites in income, even after controlling for household characteristics and geography. Further analyses of oral histories and interviews with Pacific Islanders demonstrate that income disparities exist in part because of remittances, competing financial demands, and citizenship status. I argue that it is important to add survey questions that capture migrant experiences to improve national data survey collection efforts. By utilizing and improving both types of data collection, researchers can better comprehend the barriers and opportunities for decreasing the racial income and wealth gap, which will strengthen the economic stability of Pacific Islanders in the United States.
PROPAGACIÓN VEGETATIVA DE PLÁTANO Y BANANO CON LA APLICACIÓN DE BENZILAMINOPURINA (6-BAP) Y ACIDO INDOLACETICO (AIA)
Authors: Canchignia Martínez Hayron Fabricio , Benavides Velasquez Gonzalo Rafael , Espinoza Roca Marjorie Dolores , Carranza Patiño Mercedes Susana , Cevallos Falquez Orly Fernando , Saucedo Aguiar Silvia Gicela
Published: November 2017

En la propagación vegetativa de dos variedades de Banano (Valery y Orito) y una de Plátano (Barraganete), se sometió a diferentes tratamientos hormonales, para evaluar el número de brotes, la concentración 30 mg L-1 de BAP alcanzó el mayor promedio, con 2.36 brotes para todas las variedades. En longitud y diámetro de brotes, la concentración que logró el mayor promedio fue C0, no encontrándose diferencias entre las concentraciones de 6-BAP y AIA. La variedad que presentó la mayor longitud y diámetro de brotes fue el banano Orito con 55.65 y 2.97 cm, respectivamente. El mayor porcentaje de vigor alto de brote lo demostró el tratamiento con 40 mg L-1 BAP + 12 mg L-1 AIA con 24.17%; el mayor porcentaje de vigor medio lo alcanzó el tratamiento con 30 mg L-1 BAP y sin hormona con 72.22%, la supervivencia de cepas, en las variedades Barraganete y Orito presentaron el 100% de cepas vivas, superando al banano Valery quien obtuvo un promedio de 91.67%.
EFECTO DE LOS REGULADORES DE CRECIMIENTO PARA LA PROPAGACIÓN in vitro DE LA MALANGA (Xanthosoma sagittifolium (L) SCHOTT)
Authors: Saucedo Aguiar Silvia Gicela , Ramos Gavilanes Luís , Reyes Chancay Ximena
Published: November 2017

En este trabajo se ensayaron varias concentraciones y combinaciones de reguladores de crecimiento tanto para el establecimiento y multiplicación in vitro de yemas, como para el enraizamiento y aclimatación Ex Vitro de explantes de Malanga (Xantomona sagittifolium (L) Schott.). El 68.75% de las yemas establecidas en un medio de cultivo conformado por la totalidad de las sales del MS suplementado con 0.1 mg L-1 de BAP sobrevivieron sin contaminarse. En el mejor de los casos, los brotes se multiplicaron 1.91 veces y crecieron hasta 4.86 cm en el primer subcultivo que utilizó la totalidad de las sales del MS suplementado con 3 mg L-1 BAP + 1.5 mg L-1 AIA. En la fase de enraizamiento y aclimatación sobrevivieron el 75% de los explantes testigo, a pesar de que desarrollaron las raíces más largas (6.92 cm). Con el tratamiento conteniendo 500 mg kg-1 tanto de ANA como de AIB; sobrevivieron el 80% de los brotes, los cuales desarrollaron en promedio 9.14 raíces de 5.9 cm c/u. Los tratamientos mencionados, con las concentraciones de auxina más bajas, presentaron los mejores resultados para el enraizamiento y aclimatación de las vitroplantas.
IMPLEMENTACIÓN DE LA PCR (REACCIÓN EN CADENA DE LA POLIMERASA) PARA EL DIAGNÓSTICO DE LA BRUCELOSIS DE BOVINOS EN EL ECUADOR
Authors: Cevallos Falquez Orly Fernando , Motte Emerick , Canchignia Martínez Hayron Fabricio , Carranza Patiño Mercedes Susana , Saucedo Aguiar Silvia Gicela , Cedeño Virna
Published: November 2017

En el presente trabajo se implementó la técnica de PCR para la detección de Brucella abortus, en muestras de sangre, en comparación con la prueba Rosa de bengala. La amplificación del ADN se realizó utilizando tres oligonucleotidos homólogos correspondientes a la secuencia 16 ARNr de Brucella abortus, dando una amplificación de 900 y 725 pb respectivamente. Un total de 172 muestras de sangre fueron recolectadas de 4 hatos con prevalencia histórica de presencia de brucelosis. Resultaron 142 negativas con la prueba de serológia y 143 con PCR, 30 resultaron positivas con la prueba serológica Rosa de bengala y 29 salieron positivas con PCR. Todos los animales que salieron positivos con Rosa de bengala, 4 presentaban síntomas clínicos como son; abortos, terneros débiles, baja producción de carne y leche. Los otros 26 animales resultaron negativos con PCR y estos animales no presentaron los síntomas clínicos. De los 142 animales que dieron negativo con Rosa de bengala, 25 resultaron positivos con PCR. Los resultados muestran que la detección de los animales positivos mediante la PCR fue más especificas y sensibles que la prueba serológica de Rosa de bengala, por lo tanto es una herramienta muy útil en el diagnóstico de Brucella abortus.
Efectos de los huracanes en el pasado. Bacalar, 1785
Authors: Peniche Moreno Paola
Published: November 2017

El objetivo de este artículo es analizar los efectos de un huracán que golpeó Bacalar en 1785 destacando tres variables geo-históricas: a) la ubicación de Bacalar, lejos de Mérida, y rodeado de madereros ingleses y mayas rebeldes; b) la disputa por la tala del palo de tinte (Haematoxylum campechianum); c) la agricultura de temporal como base de la subsistencia. Su pertinencia radica en las fuentes analizadas que narran detalladamente la experiencia vivida, así como en el enfoque que permite mirar más allá de la devastación. Se concluye que además de la intensidad del fenómeno natural, el desastre se detonó por el contexto vulnerable en el cual se encontraba el Partido de Bacalar, en medio de una disputa por el control y manejo de recursos estratégicos, principalmente el Palo de Tinte.
Perancangan dan Pembuatan Serious Game Sebagai Simulasi Aktivitas Bisnis dan Akuntansi Menggunakan Pendekatan Agent-Based Modelling
Authors: Wijaya Angga Ari , Bukhori Saiful , Oktavia Nelly
Published: November 2017

Permainan memiliki efek positif dalam mendukung kemampuan motorik seseorang untuk berkembang. Salah satu bahasan menarik dalam permainan adalah simulasi bisnis yang memiliki kategori serious game untuk dijadikan alternatif media pembelajaran dalam memahami konsep dasar bisnis dan aktivitas akuntansi. Gameplay dibuat dengan menciptakan artificial bisnis level UKM yang melakukan aktivitas jual beli, dimana di dalamnya terdapat game world, pelanggan dan toko yang berinteraksi untuk menghasilkan fenomena sebuah pasar. Aktivitas jual beli menjadi dasar siklus akuntansi untuk pemain belajar dan memahami kejadian finansial. Setiap agent diberi attribute yang digunakan sebagai parameter untuk membentuk personality-trait dan pengambilan keputusan pembelian serta aktivitas yang membentuk tingkah laku sehari - hari melalui State Machine dan Rule Based System (RBS). Simulasi perilaku konsumen dalam pasar virtual digunakan sebagai trigger aktivitas utama bisnis yaitu transaksi penjualan. Kejadian finansial yang terjadi dari proses simulasi menghasilkan proses jurnal untuk memberikan pemain pengalaman dalam memproses transaksi dengan contoh sumber aktivitas buatan.Kata Kunci: Serious Game, Perilaku Konsumen, Agent-based Model, A Star, Stack Finite State Machine, Rule-Based System.
The effects of audio-video instruction in brushing teeth on the knowledge and attitude of young slow learners in Cirebon regency
Authors: Sopianah Yayah , Sabilillah Muhammad Fiqih , Oedijani O.
Published: November 2017

Background: Young slow learners are children with special needs who require special attention to satisfy their personal hygiene needs, especially those of dental hygiene since they are particularly susceptible to tooth decay. Changing the knowledge and attitudes of those slow learners can be achieved by a proper method. Purpose: This study aimed to analyze the effects of teaching effective methods of brushing teeth by means of an audio video approach on the knowledge and attitude of young slow learners in Cirebon regency. Methods: This study was quasi-experimental in nature using pre test-post test methods within a two-group design. The sampling technique employed was purposive in nature. The number of young slow learners as respondents in this research totalled 31 individuals. Those children were, subsequently, divided into two groups; Group I containing 16 children, instructed in tooth brushing techniques by means of an audio video method and Group II composed of 15 children who were taught tooth brushing techniques manually. The variables measured consisted of subjects’ knowledge of and attitude towards how to brush teeth most effectively identified by means of a questionnaire, in order that the interval data could be collected. Results: The results of an independent T-test showed there to be significant differences in the mean scores of the knowledge variable and the attitude variable (p = 0.003 and p = 0.000 respectively) between Groups I and II, at that stage of the investigation. Conclusion: It can be concluded that instructional audio-videos on how to brush teeth most effectively can improve both the knowledge and attitude of children with slow learning problems.
Scaffold combination of chitosan and collagen synthesized from chicken feet induces osteoblast and osteoprotegerin expression in bone healing process of mice
Authors: Winias Saka , Ernawati Diah Savitri , Ariani Maretaningtias Dwi , Rahayu Retno Pudji
Published: November 2017

Background: Over 500.000 of the 2,3 million surgical treatments requiring bone grafting procedures that are performed annually are likely to be necessitated by or will result in bone defects that will not regenerate. Treatment to regenerate new tissues is needed, especially for hard tissue repair, which not only relies on a natural osseointegration process, but also requires a physical support to guide the differentiation and proliferation of cells into the targeted functional tissue. Chitosan and collagen extracted from chicken feet combinations are expected to enhance the bioactive surface and provide mechanical strength as a bone graft scaffold. Purpose: The aim of this study was to investigate the role of chitosan and collagen scaffold synthesized from chicken feet applications to increase the expression of Osteoprotegerin (OPG) and osteoblast cells on the fourteenth day of bone healing. Methods: Eighteen three-month old, adult, male, Rattus novergicu strain rodents with a body weight ranging from 200-350 g were kept under controlled environmental conditions. The mice were randomly divided into three groups consisting of three subjects, each treated with collagen, chitosan, chitosancollagen combination (50:50) scaffolds. On the 14th post-treatment day, three members of each group were sacrificed. Examination of Osteoprotegerin (OPG) expression was conducted by means of immunohistochemistry staining with anti-OPG polyclonal antibodies. Meanwhile, osteoblast cell examination was performed by means of hematoxilin-eosin (HE) staining. Results: The mice treated with collagen and a chitosan-collagen combination scaffold presented an increase in the expression of Osteoprotegerin (OPG) and the number of osteoblast cells respectively. Conclusion: A combination of chitosan-collagen (50:50) scaffold extracted from chicken feet increased the expression of OPG and the number of osteoblasts in the bone healing process. The combination scaffolds demonstrated the highest OPG expression and number of osteoblasts compared to the other groups.
O dever de anulação administrativa previsto no artigo 168.º, n.º 7, CPA – em busca de uma solução eurocompatível
Authors: Fernandes Sophie Perez
Published: November 2017

O objetivo do presente texto é analisar a solução consagrada no n.º 7 do artigo 168.º do Código de Procedimento Administrativo vigente desde 2015. Esta disposição estabelece o dever de anulação administrativa de atos administrativos definitivos contrários ao direito da União Europeia e procura fazer eco da jurisprudência do Tribunal de Justiça que tem no acórdão Kühne a sua landmark decision. No entanto, uma leitura atenta da disposição revela que a mesma não é inteiramente compatível com a jurisprudência do Tribunal de Justiça à qual à primeira vista se reporta. Depois de qualificar essa disposição nacional como uma regra relevante do direito administrativo da União Europeia, propomos decifrar o seu significado e alcance à luz da jurisprudência relevante, a fim de encontrar uma solução interpretativa compatível com o direito da União.
Italian regular immigration public policy: between exclusion, assimilation and integration
Authors: Calabrò Marco
Published: November 2017

The work hereof intends to analyse some profiles of the regular migration phenomenon in Italy, by examining the most recent and relevant regulatory interventions in the welfare sector, both at state and local level. In particular, we intend to demonstrate that at least three approaches regarding the reaction of the legal system towards the access of the “other” currently co-occur in Italy. To this end, the first to be analyzed will be some examples of “exclusionary” operations will be analysed, which are based on the defense of the national cultural identity and the promotion of citizenship in its formal sense (C. Schmitt) – as they are found in several ordinances of local Authorities which restrict access to social rights for foreigners, as well as in some Regional Laws on social welfare. In addition to these exclusionary operations, even a second relational model will be examined, which is inclusive and assimilative, and therefore, opposite to the previous one, while it finds its most clear expression in the Integration Agreement, which an immigrant seeking a residency permit needs to adhere to. Finally, we will focus on a “third way”, inspired by an integrative approach based on the concept of permeable identity (J. Habermas), pursuant to which both they who welcome and who are welcomed are called upon to hold an attitude of mutual listening and understanding, not aimed at the incorporation of the weaker in the stronger, but rather, at the identification of common areas of dialogue that can lead to the best integration possible of two new identities (as both have made contact with the “other”). In this context, this paper aims at enhancing the role of the new public integration policies – especially at the local level – on sustainable development of current pluralist societies. In this regard, the legal instruments which are most effective in terms of developing an approach which is resilient and open-minded to communities that welcome regular immigrants, by facilitating the creation of (institutionalized and spontaneous) moments of dialogue and the sharing of knowledge of each other’s cultures.
The Khüne obligation under the Portuguese Code of Administrative Procedure – In search of a Euro-compatible solution
Authors: Fernandes Sophie Perez
Published: November 2017

The purpose of this text is to analyse the solution enshrined in Article 168 (7) of the Portuguese Code of Administrative Procedure, which has been in force since 2015. The provision establishes a duty of administrative annulment of final administrative acts contrary to EU law and seeks to echo the case-law of the Court of Justice of the European Union (CJEU) which has the Kühne judgment as its landmark decision. However, a closer reading reveals that that provision is not entirely compatible with the case-law of the CJEU to which it, at first sight, relates to. After qualifying that national provision as a relevant rule of EU Administrative law, we will seek to decipher its meaning and scope, in light of the relevant case-law in order to find an interpretative solution that is compatible with EU law.
Effect of Nutrient Management in Lowland Rice for Improving Productivity, Profitability and Energetics under the Mid Hill of Nagaland
Authors: KUMAR MANOJ , RAJKHOWA D. J. , MEENA K. L. , KUMAR RAKESH , ZELIANG PATU K. , KIKON E. LIRENI , RANGNAMEI K. LILY , NAMEI A.
Published: November 2017

On-Farm trail was conducted in Longleng district of Nagaland during the kharif season of 2014-15 and 2015-16 to find out the most suitable nutrient management practices viz. recommended doses of fertilizers (RDF) 80:60:40 kg NPK/ha, locally available weed biomass (Eupatorium @ 10 t/ha) and farmers practices at farmers field of Krishi Vigyan Kendra, Longleng, Nagaland. The experiment was laid out in Completely Randomized Block Design. Result revealed that growth and yield parameters were recorded maximum under RDF and followed by Eupatorium @ 10 t/ha compared to farmers practice. The maximum grain yield (3590 kg/ha) was with RDF closely followed by weed biomass @10t/ha (3270 kg/ha) over the farmer's practices (2730 kg/ha), respectively. Grain yield was increased by 31.5 % in RDF and 11.8 % in Eupatorium @ 10 t/ha compared to the farmer's practices. Similarly, production efficiency was recorded the highest with RDF (28 kg/ha/day) followed by Eupatorium @ 10 t/ha (25.5 kg/ha/day) and farmers practice (21.3 kg/ha/day). With respect to economics, the maximum net returns and benefit: cost ratio (B: C ratio) were recorded with RDF (Rs.18850/ha and 1.91) as compared to other treatments. Economic efficiency was also noted highest under RDF (Rs.147.27/ha/day) followed by Eupatorium @10 t/ha (Rs.128.36/ha/day). Hence, it may be concluded that the farmer’s practices can be replaced with the adoption of RDF or locally available weed biomass (Eupatorium) as a source of nutrition for achieving the higher productivity and profitability of the lowland rice under the mid-hill altitude condition of Nagaland