bluuebunny/crossref_metadata_2025 huggingface dataset:
STREET FOOD: ASSESSING ITS IMPACT ON PUBLIC HEALTH, ECONOMY, AND SOCIETY IN LIGHT OF NUTRITIONAL BENEFITS AND MICROBIAL RISKS – A NARRATIVE REVIEW
Authors: Gonçalves Bruna Vilarinho , Da Silva Beatriz Virgínia , Andrade Anderson Assunção
Published: December 2024

Street food serves as a global culinary phenomenon, reflecting cultural diversity and enriching tourism experiences. However, concerns arise regarding its safety due to microbial contamination, posing significant public health risks. This narrative review assesses the interplay between street food, public health, economy, and society. It explores microbial risks, emphasizing deficient hygiene practices among vendors and inadequate infrastructure. Despite nutritional benefits, street food consumption contributes to foodborne diseases, disproportionately affecting vulnerable populations, especially in low- and middle-income countries. Moreover, street food vendors, predominantly women in developing nations, face socioeconomic challenges despite their crucial role in the economy. Legalizing and regulating street food operations are imperative for enhancing food safety, supporting livelihoods, and fostering socioeconomic empowerment. Overall, understanding and addressing the multifaceted impact of street food are essential for promoting public health and sustainable development.
AS FUNÇÕES DE FORMINAS, KLF6, TUSC3, CYP11A1 E FOXN1 NO DESENVOLVIMENTO EMBRIONÁRIO: CONEXÕES IMPROVÁVEIS, MAS POSSÍVEIS. UMA REVISÃO DA LITERATURA
Authors: Freitas Beatriz Cubero , Vannucchi Portari Guilherme , Simon Claudio Roberto
Published: December 2024

Durante o desenvolvimento animal, diversos genes agem em “circuitos” que evoluíram e tornaram-se indispensáveis para os diferentes processos do desenvolvimento embrionário. As distintas funções gênicas na embriogênese têm sido identificadas por diversas técnicas experimentais in vivo, ex vivo e in sílico. Muitas vezes são laboriosas, de alto custo e às vezes limitadas na identificação de interações de proteínas com estruturas moleculares distintas. Identificar novos “circuitos” formados por genes e proteínas de características diversas é ferramenta valiosa para melhor compreensão do desenvolvimento embrionário normal e disfuncional. Neste trabalho, através de uma revisão narrativa da literatura, visamos a identificação de possíveis relações entre: os genes codificadores de membros da família de proteínas forminas e também dos genes: TUSC3, KLF6, CYP11A1 e FOXN1 com a embriogênese animal. A extensa, variada e evolutivamente conservada família de forminas codifica proteínas reguladoras do citoesqueleto, envolvidas em vários processos do desenvolvimento. TUSC3 uma proteína do complexo Oligossacariltransferase, atua na N-glicosilação, na supressão tumoral e também na maturação sexual. O gene KLF6 (Kruppel Like Factor 6) codifica uma proteína nuclear com domínios dedos-de-zinco, que regulam múltiplos genes. A proteína codificada por CYP11A1 faz parte da membrana mitocondrial interna e atua na esteroidogênese e espermatogênese, enquanto o gene FOXN1, é expresso principalmente em células epiteliais do timo e da pele com distintas funções. A análise dos artigos selecionados evidencia a participação desses genes em uma grande variedade de processos do desenvolvimento animal e em diferentes espécies animais. Forminas e KLF6 atuam em processos similares de desenvolvimento e podem eventualmente interagir. CYP11A1 também atua similarmente à KLF6 e forminas em menor grau. TUSC3 e FOXN1, a despeito de seus papéis fundamentais, atuam no desenvolvimento animal em contextos mais específicos. A investigação experimental dessas possíveis interações deve contribuir para o melhor entendimento de suas funções no desenvolvimento, nos processos comuns do desenvolvimento animal aqui apontadas.
PALAVRAS-CHAVE: embriogênese animal, circuitos genéticos, função gênica
Legal Support of the Economic Security of Russia: Experience of Extraordinary Regulation
Authors:   Leading Research Scientist of the Research and Expert Center of the Institute of Law and National Security of the Russian Presidential Academy, Vanin Vitaliy V. , Karpenko Gleb M. ,   Postgraduate Student of the Department of Administrative and Information Law of the M.M. Speransky Law Faculty of the Institute of Law and National Security
Published: December 2024

The article examines the problems of forming a legal mechanism for ensuring economic security, taking into
account the experience of extraordinary regulation aimed at overcoming the negative consequences of extraordinary
circumstances and external sanctions. The main approaches to the legal model of ensuring economic security are
outlined, which consist in the normative formalization of a system of quantitative indicators, which should be monitored
by authorized executive authorities using the unified digital platform of the Russian Federation GOSTECH, as well as in
the normative consolidation in the federal law of a system of legal protective measures aimed at overcoming threats to
economic security.
Domestic Violence
Authors:   Associate Professor of the Department of Criminal Law of the Orenburg State University, PhD (Pedagogy), Associate Professor, Filippova Elena O.
Published: December 2024

The article examines the general characteristics of violent crimes that occur within the framework of family and household
relations, and also examines the main provisions affecting the essence, types and conditions of violent crimes, the causes
and conditions of their occurrence in family and household relations. It should be noted that the complexity and versatility
of the topic under study predetermined the need to refer to the works of researchers and materials of judicial practice.
The paper reveals aspects related to the characteristics of violent crimes in the field of family and household relations, as well
as examines the features and problems affecting the problems of their prevention. It is necessary to review the balance of
measures that are traditionally used to prevent crimes in the field of family and household relations and measures of social
adaptation and support aimed at victims.
Presentación
Authors: Sandoval Javier H.
Published: December 2024

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Switch-Level Interleaved Converter: Circuit Operation, Output Ripple and Circulating Current
Authors: Biajo Vítor H. M. , Lobato Gideon I. C. , Silva Sidelmo M.
Published: December 2024

This paper discusses an interleaved converter topology for DC-AC conversion in power electronics applications. The proposed topology leverages a switch-level interleaving technique to overcome the limitations of conventional interleaved inverters. Through comprehensive analysis and simulation studies, it is demonstrated that the interleaved inverter achieves higher power density and improved ripple frequency as compared to conventional counterparts. In this paper, different figures of merit are considered in order to assess the proposed converter scheme performance such as current ripple parameters, circulating current and semiconductor losses. One of the main advantages of the proposed technology over conventional interleaving converters is the use of a single inductor, which enables its use not only in grid-tied applications but also in electric drives.
Educação Ambiental Crítica na modernidade/colonialidade: reflexões a partir de Enrique Dussel
Authors: Costa Cesar Augusto , Loureiro Carlos Frederico
Published: December 2024

O foco desta reflexão é abordar a contribuição da Educação Ambiental Crítica frente à dinâmica da modernidade/colonialidade capitalista a partir das contribuições teórico-políticas de Enrique Dussel. O texto, apoiado na pesquisa bibliográfica, está dividido em quatro momentos integrantes: no primeiro momento, contextualizamos alguns elementos da relação totalidade, natureza e trabalho na sociedade no capitalismo à luz das contribuições de Dussel; no segundo, pontuamos os elementos da colonialidade/modernidade/ eurocentrada, e o debate da natureza, conforme discutida no projeto modernidade/colonialidade; no terceiro momento, indicamos algumas notas sobre o Sistema-mundo moderno-colonial no contexto da Educação Ambiental Crítica. Ao fim, tratamos das contribuições dusselianas para a EA crítica no contexto da modernidade/colonialidade capitalista na América Latina.
Propiedades psicométricas del SRQ-Motivación Lectora en estudiantes de primaria de Lima
Authors: Dammert Martin , Matos Lennia , Gargurevich Rafael
Published: December 2024

La presente investigación analizó las propiedades psicométricas del Cuestionario de Autorregulación-Motivación Lectora (SRQ-Motivación Lectora) en contextos académicos de lectura; específicamente, en el espacio de la biblioteca escolar. En una muestra de 235 estudiantes de cuarto y quinto grado de primaria de una escuela privada de Lima, se estudió la estructura interna de la escala a partir de análisis factoriales confirmatorios. Los resultados evidenciaron un modelo de dos factores que hacen referencia a la motivación autónoma y la motivación controlada hacia la lectura. Los resultados obtenidos de las evidencias de validez convergente y discriminante fueron conforme a lo esperado. La confiabilidad de las puntuaciones obtenidas en las escalas también fue adecuada. Los resultados son discutidos a la luz del lado claro y el lado oscuro de la motivación desde el marco de la Teoría de la Autodeterminación.
Necessidades de intervenção diferenciadas de acordo com o modelo risco-necessidade-responsividade: Evidências de uma tipologia empírica de adolescentes infratores brasileiros
Authors: Sette Galinari Lais , Rezende Bazon Marina
Published: December 2024

Para o modelo teórico e metodológico do Risco-Necessidade-Responsividade, considera-se as necessidades interventivas aqueles aspectos dinâmicos que devem ser trabalhados em um contexto interventivo com foco na prevenção da reincidência. O estudo teve objetivo de caracterizar as necessidades interventivas dos adolescentes da amostra considerando o pertencimento a diferentes perfis, identificados previamente. Os 400 adolescentes em conflito com a lei pertencentes aos diferentes perfis foram caracterizados por meio de análises de ANOVA e pós-teste de Bonferroni. Foi identificado que os quatro perfis se diferenciavam entre si em relação as necessidades interventivas apontadas como relevantes de serem avaliadas segundo o modelo R-N-R. Os resultados reforçam a hipótese da heterogeneidade entre adolescentes em conflito com a lei, o que demandaria a realização de intervenções diferenciais e personalizadas.
Why is so difficult to coexist with passengers in the subway?
Authors: Beramendi Maite Regina , Marini Noemi , Zubieta Elena Mercedes
Published: December 2024

This study explores the coexistence challenges among Buenos Aires subway passengers. It focuses on analyzing coexistence problems, perceptions, and participation in conflicts, as well as tolerance towards norm deviations. An online survey with 768 riders revealed that conflicts among passengers reproduce violence and create a social climate of mistreatment, normalizing disrespectful behaviors. Participants reported a stressful environment leading to contradictory behaviors: they are both vigilant and detached, paying less attention to others’ needs and more tolerance towards uncivil behavior. The findings suggest that the lack of adherence to social norms exacerbates the tense atmosphere, highlighting the need for better regulation and enforcement to improve passenger coexistence.
Effect of replacing fish meal and ground nut cake by doc soya on weight gain, digestibility and blood biochemical profiles in growing pigs
Authors: Kumar Hemant , Kumar Basant , Singh S.K.
Published: November 2024

The present study was carried out on 36 growing piglets to evaluate the possibility of soybean meal as protein source in place of fish meal (FM) and ground nut cake (GNC) in feed mixture. The diets were prepared by replacing the 100% FM by DOC Soya (T2) and 100% replacing both FM and GNC by DOC soya (T3) of basal diet (T1). Significantly higher daily weight gain in growing piglet during the experimental period of 91 days was recorded in T3 (0.46±0.04 kg) and T2 (0.43±0.04 kg) than T1 (0.35±0.04 kg). CP and NFE digestibility were higher in group T3 followed by T2 and T1, the value being 67.00 and 75.60%, 74.76 and 80.81% and 78.89 and 84.83%, respectively. The balances of N, Ca and P were in positive direction and were higher in T3 than T2 and lowest in T1. Hematological indices were also higher in T3 followed by T2 and T1.
Pathomorphology of Acute Duck Cholera Infection in Meat Ducks
Authors: Srinivasan P. , Murthy T.R.G. , Gopal K. , Saravavn S. , Gowthaman V.
Published: December 2024

Background: Duck farming is one of the major income generating enterprise, promoting rural economy in India. The occurrence of infectious diseases is the major bottle neck in the profit generation process of duck rearing. Duck cholera is one of the major bacterial infections, commonly noticed in 4 to 11 weeks age of egg laying ducks caused by Pasteurella multocida, leading to high mortality in ducklings whereas adult as well as meat type ducks are resistant. The present communication describes pathomorphology of acute duck cholera in Vigova Super M meat type breeder flock. Methods: An investigation was carried out to ascertain the possible cause of increased mortality in an intensively maintained 1000 Vigova Super M meat type breeder flock of 25 week old during the month of July 2023. Necropsy examination conducted on five dead birds and samples collected and subjected for bacteriological and pathological examination. Result: Affected breeder duck flocks showed cumulative mortality of 18 per cent. Clinical signs of depression, inappetance, mild conjunctivitis and mucus discharge from nostril for one or two days followed by death were noticed. At necropsy, hepatomegaly and splenomegaly with multifocal cream-colored foci randomly distributed throughout the parenchyma, vascular changes in various visceral organs were noticed. Impression smear of visceral organs of dead birds revealed bipolar organisms which was confirmed as Pasteurella multocida by cultural and biochemical examination. Microscopically, there was multifocal splenic and hepatic necrosis with intralesional rod-shaped bacteria. In conclusion, this investigation indicated that the adult breeder ducks susceptible to duck cholera, exhibiting pathomorphological features similar to young ducklings.
Discerning genetic diversity among super early pigeonpea germplasm using microsatellite markers
Authors: Pushpavalli* SNCVL , Rajeswari R. Raja
Published: November 2024

In the present study genetic diversity studies have been carried out using twenty four polymorphic SSR markers in a set of thirty five super early pigeonpea germplasm. The primers amplified a total of 69 alleles with 24 primers having highest PIC of 0.74. The SSR markers grouped the germplasm into four clusters based on jaccard’s similarity coefficient. To test the goodness of fit of a clustering to a set of SSR data, cophenetic correlation coefficient or cophenetic value was estimated using the COPH and MXCOMP options in NTSYS-pc program. The cophenetic value of 0.94 obtained using the SSR data indicated a very good fit. The polymorphic SSR primers could clearly distinguish the determinate germplasm and non-determinate germplasm. PCA revealed that phenotypic variation explained by the SSRs with first four PCs accounted to 65.4% of total variation. Analysis of molecular variance of pigeonpea germplasm has shown that approximately 1.2% of genetic diversity was within super early germplasm, 71% among germplasm, and 27% among determinate and indeterminate types.
Marco regulatorio de Biotecnología moderna y edición génica agropecuaria de Costa Rica
Authors: Pérez Jason , Garro-Monge Giovanni , Barboza-Fallas Luis , Hernández-Soto Alejandro , Gatica-Arias Andrés
Published: November 2024

La biotecnología es un motor de desarrollo global para el sector agropecuario, influyendo en la economía mundial y el avance de las metas de desarrollo sostenible. El control biológico, la seguridad alimentaria y el secuestro de carbono, son solo algunas de las áreas de mayor impacto. En este contexto, Costa Rica se destaca en la región gracias a sus desarrollos e investigaciones en biotecnología, contando con 87 empresas, 42 centros de investigación y generación de empleos, lo que equivale al 1,05% del PIB nacional. Desde 1998, el país ha establecido el marco legal que regula el uso de organismos convencionales, orgánicos, organismos vivos modificados (OVM) y editados, fomentando así el desarrollo económico basado en biotecnología. Este marco incluye mecanismos que aseguran la gestión de los OVMs y la coordinación interinstitucional para evaluar y otorgar permisos de uso. El presente artículo detalla la normativa de biotecnología moderna y edición génica. Gracias a estos esfuerzos, se han establecido manuales, instructivos y documentos, que orientan a los usuarios en el uso de OVMs. En cuanto a la edición génica, la normativa costarricense guarda similitudes con otras normas internacionales. Los organismos resultantes de esta tecnología son comparados y definidos como equivalentes a los obtenidos por métodos convencionales. La percepción positiva de la tecnología en el sector agrícola fortalece aún más este panorama para un desarrollo económico. De esta manera, Costa Rica se posiciona como un entorno amistoso para el desarrollo económico e inversiones impulsadas por biotecnología, en línea con las metas de desarrollo sostenible.
Estado actual de las cutinasas en la problemática de la degradación de plásticos de un solo uso
Authors: Arrieta-Fonseca Marcel
Published: November 2024

El consumo generalizado de plásticos de un solo uso ha ocasionado una crisis ambiental debido a su sobreacumulación en los ecosistemas. Este artículo explora el estado actual de las cutinasas, uno de los principales tipos de enzimas con potencial para degradar plásticos de un solo uso. Las cutinasas (EC 3.1.1.74) son serina hidrolasas del grupo de las hidrolasas α/β capaces de catalizar reacciones que degradan polímeros, principalmente tereftalato de polietileno (PET) y polibutilenadipato-co-tereftalato (PBAT), y son producidas por bacterias, hongos filamentosos y levaduras. Cada enzima posee características diferentes según su microorganismo de origen, siendo las de hongos y levaduras más similares entre sí que las bacterianas. Las herramientas biotecnológicas, como la biología sintética, han demostrado ser estrategias innovadoras capaces de mejorar la eficiencia y estabilidad de las cutinasas en la degradación de plásticos, capaces de ofrecer una posible solución sostenible para la crisis ambiental causada por estos materiales.
Diálogo entre hongos y plantas en la raíz y el suelo
Authors: Rivera-Méndez William , Watson-Guido William
Published: November 2024

Los hongos son organismos presentes en todos los ecosistemas terrestres y cumplen diversos papeles ecológicos en los nichos que habitan. El suelo es una matriz de intenso intercambio de señales, que los hongos ha aprovechado para establecer todo tipo de interacciones. Sus relaciones particulares con las raíces de las plantas están determinadas por procesos de comunicación que se establecen entre ambos organismos a nivel celular y tisular. Si bien el concepto de inteligencia en organismos que no sean animales es todavía un tema controversial, existen evidencias científicas que apuntan al menos a un nivel basal de inteligencia para guiar estos procesos de comunicación y respuesta. En este contexto se describen los conocimientos más recientes sobre los hongos rizosféricos, micorrícicos y endófitos; donde se destacan sus efectos en la regulación del crecimiento de las plantas, la nutrición y el intercambio de carbono y agua, la inducción o la supresión de la resistencia sistémica, la colonización celular y la producción de metabolitos secundarios, ya sea en relaciones simbióticas o patogénicas. Pese a los nuevos avances, existen grandes oportunidades de investigación básica y aplicada para el aprovechamiento de este diálogo molecular. El objetivo de esta revisión fue presentar algunos de los fenómenos descritos en la interacción hongo-planta en el suelo y mostrar su relevancia desde la perspectiva de una “comunicación inteligente”.
Optimización de la embriogénesis somática en Coffea arabica: evaluación de la orientación y punto de origen del explante foliar
Authors: Vargas-Morera Daniela , Vargas-Delgado Roselind , Ceciliano-Castro Steven
Published: November 2024

El cultivo del café (Coffea arabica) en Costa Rica afronta diversos desafíos debido a los cambios climáticos y a las fluctuaciones del mercado. La búsqueda de variedades más resistentes y de mayor calidad ha llevado a explorar métodos de propagación alternativos, como la embriogénesis somática (ES), que permite la multiplicación de nuevas variedades en condiciones controladas de laboratorio. Cuando se realiza directamente, sin callo de por medio, la orientación del segmento foliar y el punto de origen de la muestra poseen influencia evidente en el éxito del explante. Para comprobarlo, en este estudio se evaluó el efecto de la disposición adaxial y abaxial de las hojas de C. arabica obtenidas de puntos distales, proximales y mediales de vitroplantas para la inducción de embriogénesis somática directa. Secciones de las hojas fueron introducidas en un medio de cultivo Murashige y Skoog (MS) suplementado. Se realizó un análisis multivariado para conocer cuál combinación de tratamientos generó una mejor respuesta en la ES, denotado mediando un mapa de calor. Se obtuvo un 36% de callo de regeneración al introducir explantes de forma adaxial con una oxidación reducida. Asimismo, la parte distal y medial exhibieron mayor capacidad de regeneración. La orientación adaxial de las hojas de café aumentó la inducción de embriones somáticos, posiblemente al favorecer el intercambio gaseoso por la característica hipoestomática de C. arabica. Con esta optimización, se podría facilitar el proceso de introducción de plantas a partir de hojas con un mayor porcentaje esperado de éxito.
Agentes químicos que dañan al ADN: inducción de genotoxicidad en la vida diaria, riesgo y prevención
Authors: Montero-Campos Virginia , Huang-Qiu Ying Yi , Rodríguez-Sevilla Henry
Published: November 2024

Los agentes genotóxicos son sustancias que tienen la capacidad de inducir daño en el ADN; este daño puede ser causado por agentes químicos, biológicos y físicos. Su capacidad de inducir daño está influida por la dosis recibida, el tiempo y la vía de exposición, y la constitución genética del individuo, y puede estar relacionada con hábitos de vida y el lugar de residencia. Relacionado directamente con la genotoxicidad está la epigenética; esta ciencia es el estudio de los cambios en la función de los genes que son hereditarias y que no se pueden atribuir a alteraciones de la secuencia de nucleótidos en el ADN. Estos procesos regulan la expresión de genes por medio de la modulación de la estructura de la cromatina. La interacción de factores genéticos y no genéticos involucrados en el control de patrones hereditarios puede degenerar en enfermedades o trastornos complejos como cáncer, infertilidad, procesos inflamatorios, enfermedades degenerativas y disrupción endocrina, padecimientos que pueden ser transmitidos a la descendencia. Varios estudios epidemiológicos han demostrado que los cambios en el estilo de vida y los hábitos alimentarios podrían prevenir o reducir la incidencia del cáncer, especialmente mediante el aumento del nivel de antioxidantes y disminuyendo la formación de radicales libres con efecto intracelular. En el Centro de Investigación en Biotecnología del Instituto Tecnológico de Costa Rica se investigan diversos agentes genotóxicos a los cuales está expuesto la población en Costa Rica, incluyendo bacterias como Helicobacter pylori, microplásticos en especies marinas de consumo humano, y metales pesados en aguas potables y en suelos. Estas investigaciones son relevantes para determinar la presencia de estos agentes genotóxicos en el país, evaluar el riesgo de exposición de la población, y así generar estrategias de prevención y mitigación del daño.
Edición especial: 30 Aniversario del Centro de Investigación en Biotecnología
Authors: Calvo-Castro Laura A.
Published: November 2024

Presen
The cause of the current of the problem of palliative medicine in the “mirror” of shmerian-akkadian mythology
Authors: Ivanov Konstantin V.
Published: November 2024

The unreliability of modern methods of treating existential distress in incurable patients draws the attention of a number of specialists to the possibility of using such an effective means of combating thanataphobia as gaining a symbolic experience of death – rebirth in palliative care, the simplest and most effective way of generating which is the use of entheogens. However, the topic of psychedelic therapy of the dying patients causes a wary attitude of society, despite the habitually high level of narcotic saturation of the field of palliative medicine. This attitude seems to be clearly conditioned by the cultural tradition of the prohibition of eating fruits from the Tree of Life, traced back to the era of Sumer and Akkad. Interpretation and analysis of the content of the mythological works of this ancient civilization give grounds to assert that the initial reason for the historical taboo on entheogens was the effect of the experience of symbolic rebirth in the form of the formation of the so-called psychological “wholeness”, i.e. a state of complete inner serenity, accompanied by a sharp decrease in the need for “external” adaptive activity. This circumstance, without a doubt, posed a fundamental threat to the well-being and security of society in the conditions of the archaic availability of this class of psychotropic substances. Such an “adaptive-civilizational” nature of the ban raises the question of its expediency in relation to those incurable patients for whom palliative means of distress therapy used by modern medicine turn out to be untenable.
Book of Abstracts: Federation of Societies of Experimental Biology (FeSBE) XXXVIII Annual Meeting
Authors:   Federação de Sociedades de Biologia Experimental (FeSBE)
Published: December 2024

The XXXVIII Annual Meeting of the Federation of Experimental Biology Societies (FeSBE) was held from July 2 to 5, 2024, on the UNICAMP campus. This event, one of the most traditional in Brazilian science, has significantly marked the trajectories of countless scientists. FeSBE, and its 24 federated societies in the areas of biomedical research and experimental biology, brings together 10 thousand scientists spread across all states of Brazil. FeSBE is one of the largest federations of scientific societies present in Brazil and its contribution to the production of national science is significant. FeSBE meetings are recognized for their comprehensive program, addressing themes that cut across all areas of science, as well as topics specific to each federated society. It is an excellent space to create networks and foster collaborations between colleagues from different areas and societies, making it a true celebration of experimental biomedical science.
SARCASM IN HABIB JA'FAR'S LOG-IN CONTENT ON DEDDY CORBUZIER'S YOUTUBE CHANNEL
Authors: Anjayuni Efa , Malayati Robi'ah Machtumah , Rahmah Shofa Nadya
Published: December 2024

Sarcasm in this study is represented through language signs in Habib Ja'far's da'wah on Log-In content on Deddy Corbuzier's YouTube account. This research uses an interpretive qualitative method through Ferdinand de Saussure's semiotics to analyze the signs and meaning of da'wah language. The results showed that Habib Ja'far's da'wah is propositional Sarcasm, Lexical Sarcasm, 'Like'-Prefixed Sarcasm, Illocutionary Sarcasm. Habib Ja'far's sarcastic humor aims to reduce tension and sensitivity to sensitive issues related to religion, social, and culture. Habib Ja'far's use of sarcastic humor serves to create a lighter and more open atmosphere without offending, aiming to reduce tension and sensitivity to sensitive issues related to religion, social, and culture.
Antibacterial Activity of Commiphora Gileadensis Bark Extract Against Staphylococcus Aureus as Cream, Gel and Ointment Formulations
Authors: Maqlam Tareq , Bin kardous Ali
Published: November 2024

The Bisham plant (Commiphora gileadensis) is one of the most popular traditional medicinal plants used in Yemen. The bark of the plant is useful to treat burns and skin infections. This study was aimed to investigate the antibacterial activity of the bark as extract and as pharmaceutical ointment, cream and gel against Staphylococcus aureus. The study was carried out using agar cup plate method. The results showed that antibacterial activity of C. gileadensis bark extract by maceration extract had a inhibition zone on S. aureus using 40% extract was 16.3 mm, at 60% extract it was 17.3 mm, while in 80% the inhibition zone was 18.7 mm, on the other hand, the using of soxhlet was showed a sensitivity zone 14.8 mm for 40% extract. 16.2 mm for 60% extract, and 17.7 mm for 80% extract. Formulation of 10% C. gileadensis bark methanolic extract as cream showed 13.3 mm inhibition zone and 15.7 mm for gel which showed greater antibacterial activity than the standard cterimide cream (13.3 mm inhibition zone). It turns out that the Bisham extract can be formulated efficiently as cream and gel pharmaceutical products.
Advances in external beam radiation for hepatocellular carcinoma, stereotactic body radiation therapy (SBRT) and particle therapy
Authors: Seth Lokesh , Stephans Kevin L.
Published: November 2024

Hepatocellular carcinoma (HCC) represents a leading cause of cancer-related mortality globally. Due to frequently complex disease presentation and comorbid underlying cirrhosis, many patients are not ideal candidates for surgical resection, transplantation, or other local ablative treatments. External beam radiation therapy (EBRT) has emerged as a promising alternative. EBRT has gained prominence due to advancements in targeting and treatment delivery technology. Advanced modalities such as intensity-modulated radiotherapy (IMRT), image-guided radiotherapy (IGRT), stereotactic body radiation therapy (SBRT), and proton beam therapy (PBT) have dramatically improved the precision of radiation delivery, resulting in a far more favorable therapeutic ratio. Here we cover the evolution of current practice and future prospects of EBRT in treating HCC, emphasizing the enhanced efficacy and reduced toxicity provided by these advanced technologies, and improved integration with other loco-regional and systemic therapies in reviewing the current indications for treatment.
Age-related hearing loss: possible associations with Alzheimer’s disease
Authors: Ma Ying , Yang Yanyan , Zhou Yufan , Le Weidong , Chai Renjie
Published: November 2024

With the increasing aging of the population, there has been a growing focus on the association between age-related hearing loss (ARHL) and Alzheimer’s disease (AD). Given the extended latency period of AD, it has been assumed that mechanisms contributing to its pathogenesis may also contribute to ARHL. Abnormal deposition of beta-amyloid (Aβ) and tau protein in the brain serves as the primary etiological marker for AD, being produced long before the symptomatic onset of AD. The neurotoxicity induced by their unique oligomers not only exerts significant effects on the central nervous system but also exhibits similar impacts on certain peripheral organs. In this review, we analyze the factors leading to β-amyloid and tau production, explore their cascading effects and roles in AD progression, discuss the possible influence of auditory deprivation on cognitive functions, and investigate the potential causes of hearing loss by examining other peripheral organs in AD patients and model animals as examples. These findings provide further evidence supporting ARHL as an early indicator of AD.
Dual magnetic particles modified carbon nanosheets in CoFe/Co@NC heterostructure for efficient electromagnetic synergy
Authors: Wu Zhanming , Huang Jun , Zeng Xiaojun
Published: November 2024

Dual magnetic particles-modified carbon materials have great potential in terms of ultrathin thickness (≤ 2 mm) and super electromagnetic wave (EMW) absorption (≤ -70 dB). Herein, using CoFe-metal-organic framework (MOF)-derived CoFe/Co@NC heterostructures composed of hollow CoFe nanospheres, solid Co nanospheres, and nitrogen-doped carbon (NC) nanosheets, we demonstrate how the dual magnetic particles regulate the electromagnetic response behavior of the heterostructure and thus steer the efficient EMW absorption performance. That is, CoFe/Co@NC heterostructure inherits an ultra-strong reflection loss (R L) of -73.8 dB at 1.78 mm. The effective absorption bandwidth (EAB) value is also available up to 5.4 GHz. Moreover, computer simulation technology (CST) simulations reveal the good radar stealth effect of heterostructures. Experimentally, the outstanding EMW absorption of CoFe/Co@NC heterostructure is due to a large number of heterointerfaces, good conductive networks and dual magnetic nanoparticles, which bring considerable interface polarization, conduction loss, and magnetic loss characteristics. These findings underscore the importance of electromagnetic synergy induced by dual magnetic particles for steering the electromagnetic response of EMW absorbers.
The impact of Neo-Liberal frameworks on student mobility and internationalisation in African higher education
Authors: Woldegiorgis E. T.
Published: December 2024

Internationalization and academic mobility have traditionally been pivotal components within higher education, each serving distinct roles. Internationalization has been instrumental in promoting academic exchange, enabling knowledge dissemination, fostering research collaborations, and driving shared innovation. However, the emergence of neoliberal ideologies has embedded global capitalism's market dynamics into higher education systems globally, aligning the sector increasingly with market-oriented values. This paper investigates the effects of neoliberalism on the internationalization of higher education in Africa, with particular emphasis on evolving trends in international student mobility. It contends that neoliberal influences on international mobility extend beyond mere market considerations, touching on issues of hegemony within global knowledge frameworks that often marginalize African nations and institutions. The study is based on published sources and accessible statistical data from governmental and non-governmental entities. By exploring the intersections of neoliberalism and internationalization in higher education, this paper highlights the complex and nuanced nature of these dynamics and their concrete implications for the movement of students across borders. Furthermore, the article considers how neoliberal entanglements may shape the future trajectory of internationalization within African higher education contexts.
Keywords: internationalization, student mobility, neoliberalism, Africa, brain drain
Non-degreed youth’s employability, career adaptability, and psychological capital at an educational institution
Authors: Van Vuuren J. , Oosthuizen R. M. , Steyn L.
Published: December 2024

Technological developments and the Fourth Industrial Revolution (4IR) make employability more important than employment. The youth are forced to adopt a protean career and constantly adjust their skills, knowledge and behaviour to maintain their employability and skills relevance. Psychosocial career resources assist them in coping with career challenges and setbacks through career adaptability and remaining employable. The study investigated the relationship between employability, career adaptability, and psychological capital amongst non-degreed youth at an educational institution. To cope with contemporary work environment demands, the youth must be equipped with the competencies and know-how to flex their careers appropriately. At the time of the study, no research had examined the relationship between employability, career adaptability and psychological capital. The study used a cross-sectional, quantitative, non-experimental research approach to explore the interrelatedness of the variables. The results demonstrated a strong, positive and significant relationship between employability and career adaptability; employability and psychological capital; and career adaptability and psychological capital. The relationship between employability and career adaptability was more conspicuous than the relationship between employability and psychological capital. Cultivating employability attributes, career adaptability, and psychological support may strengthen the youths’ self-perceived employability and improve how they adjust their careers according to work environment demands. The study explains how employability, career adaptability, and psychological capital relate. Its findings can be used to advance youth employability.
Keywords: career adaptability, employability, psychological capital, psychosocial career resources, Fourth Industrial Revolution
THEOLOGIENS PAR EFFRACTION: LES PLUS PAUVRES RENOUVELLENT L’INTELLIGENCE DE LA FOI
Authors: Grieu Etienne
Published: November 2024

La conception de la théologie ici présentée refuse de séparer l’élaboration de son savoir de la quête du plus pauvre, du dernier des humains, seul et abandonné dans sa misère. Une telle perspective doit beaucoup à la pensée du P. Joseph Wresinski et du mouvement ATD Quart Monde, qui appelle à un déplacement assez radical de perspective, jusqu’à ce que le plus pauvre ait été entendu. Une théologie qui prend au sérieux cet appel en est renouvelée dans sa manière de penser la révélation et de se rapporter au Christ, notamment dans sa dimension corporelle.
MOTS CLES: Option pour les pauvres. Révélation. Corps du Christ. Théologie du politique. Théologie de la libération. Épistémologie de la théologie.
ERA C. S. LEWIS UM INCLUSIVISTA?
Authors: Caldas Carlos
Published: November 2024

C. S. Lewis (1898-1963) foi um dos principais pensadores cristãos do século passado. Autor prolífico, escreveu sobre muitos temas, dentre os quais destacam-se a crítica literária, a teoria da educação, a literatura de fantasia e a exposiçao teológica. O presente artigo pretende verificar a questão de como Lewis entendia o lugar das religiões na experiência da salvação. No cristianismo a soteriologia, entendida como reflexão sobre a experiência da salvação, tem sido ao longo dos séculos identificada com a posição exclusivista, que nega a todas as demais tradições religiosas qualquer possibilidade de valor salvífico. A partir da segunda metade do século XX outras compreensões têm surgido. Uma delas, o inclusivismo, entende que, em Cristo, não cristãos podem ter a experiência da salvação. A hipótese que se pretende demonstrar no artigo é que Lewis defendia a perspectiva inclusivista.
PALAVRAS-CHAVE: Inclusivismo. Soteriologia. Cristologia. Diálogo inter-religioso. C. S. Lewis.
Estimation of Chronic Academic Stress Among College Students Using Short Form Video Contents
Authors: Aadhithya A Aadharsh , Sundaram M Kalyan , Sunil Sreya , Bijlani Kamal , Kumar S Sachin , K.P. Soman
Published: December 2024

Chronic stress, especially among young adults, is a pervasive threat that can lead to various mental and physical illnesses. Measuring stress is crucial for timely intervention, but existing methods like self-reporting scales and physiological sensors are often invasive, require specialized equipment, or suffer from response biases. This research investigates whether engagement patterns with popular short-form video content can serve as an indirect estimator of chronic mental stress levels. The underlying premise is that interacting with short videos through likes/reactions has become a habitual behavior, especially among youth, potentially alleviating biases from voluntary responses. The study aims to develop multimodal representations for short form videos in Indic languages and analyze engagement data from 22 participants to identify possible stressors and construct a causal model linking video content, engagement patterns, and inferred stress levels,this method could allow us to discreetly understand their mental health status, so we can provide help and support when needed.
Some Submaximal Elements of the Lattice of Finitary Operations on a Finite Set
Authors: Joseph Djoumessi , Etienne Romuald Temgoua Alomo
Published: December 2024

The set of Boolean functions has a simple basis formed by the meet and the negation. Is it possible to have a similarly basis for any subset of finitary operations on a finite set with more than three elements? It is known that any set of finitary operations on a finite set can be expressed as a set of operations preserving some relations on this set. A clone on a finite set is a set of finitary operations on this set containing all the projections and stable by composition. It is also known that the set of clones on a finite set is a complete lattice. The maximal elements of this lattice was completely described by Rosenberg in 1965. In this paper, we determine clones of the form $\Pol \sigma \cap \Pol \lambda$ sited directly below $\Pol \lambda$ where $\lambda$ is a fixed regular relation and $\sigma$ a binary relation to be characterized.
Fluid Loss in Conglomerate Reservoir Considering Heterogeneous Distribution of Gravel
Authors: Zhang Xinghua , Chen Guangfeng , Wang Xuxing , Guo Bumin , Gao Kechao
Published: December 2024

The sand conglomerate has strong heterogeneity, great difference in rock mechanical properties, and serious filtration loss of fracturing fluid. In order to describe the effect of heterogeneous gravel distribution on the filtration loss of conglomerate reservoir, a dual media filtration model was established based on the equivalent flow principle, and the heterogeneous distribution relationship was characterized by Fuller gradation and solved by numerical method. The degree of non-uniformity, formation gravel characteristics and pressure process parameters were taken into account for simulation analysis and calculation. The results show that the average filtration rate of 60% gravel content is 54.2% lower than that of 20% gravel content. When the degree of non-uniformity is 6, the average filtration rate is 73% higher than that of uniformity. Injection rate and injection pressure have a great influence on the filtration loss of fracturing fluid. The research results can provide theoretical support for fracturing optimization design.
Testing the Feasibility of a Cross-Setting Measure to Address the Rising Trend in Hospital Outpatient TJA Procedures
Authors: Wallace Lori R. , Tan Zhen , Barthel Andrea , Sáenz Matthew P. , Grady Jacqueline N. , Balestracci Kathleen M.B. , Bozic Kevin J. , Myers Raquel , McDonough Dena L. , Lin Zhenqiu , Suter Lisa G.
Published: December 2024

Background:

Elective primary total hip and total knee arthroplasty (collectively, total joint arthroplasties [TJAs]) are commonly performed procedures that can reduce pain and improve function. TJAs are generally safe, but complications can occur. Although historically performed as inpatient procedures, TJAs are increasingly being performed in the outpatient setting. We sought to develop a scientifically acceptable cross-setting measure for evaluating care quality across inpatient and outpatient settings.

Methods:

Using Medicare administrative claims and enrollment data for qualifying TJA patients, we respecified the Centers for Medicare & Medicaid Services (CMS) inpatient-only risk-standardized TJA complications measure to assess complication rates following elective primary TJAs performed in an inpatient or outpatient setting. We aligned inpatient and outpatient coding practices and used hierarchical logistic regression to calculate hospital-specific, risk-standardized complication rates (RSCRs). Lower rates correspond to better quality. Using accepted approaches for CMS measures, we tested measure reliability and vetted key measure decisions with patient and provider input.

Results:

A single combined model including the procedure setting as a risk variable produced the highest discrimination (C-statistic for a single combined model with a setting indicator: 0.664, C-statistic for the inpatient-only model: 0.651, C-statistic for the outpatient-only model: 0.638). Among the 2,747 hospitals with at least 25 TJAs, the mean RSCR (using the combined model with a setting indicator) was 2.91% (median RSCR: 2.85%; interquartile range: 2.59% to 3.18%). The median odds ratio for complication occurrence at a higher-risk hospital compared with a lower-risk hospital was 1.33.

Conclusions:

We respecified a measure to assess hospital inpatient or outpatient TJA performance and evaluated the reliability and validity of the measure. The findings showed variation in hospital-level complication rates across settings as indicated by this measure, supporting the feasibility of evaluating hospital performance using a more representative population than inpatient TJAs alone.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Accelerating SDGs to Alleviate Poverty: Synergy Between National Amil Zakat Agency (BAZNAS) and Islamic Financial Institutions (IFI)
Authors: Retnowati May Shinta , Yusuf M. Asror , Cahyani Meitria , Hidayat Iman Nur , Al Faruqi Musta’an
Published: November 2024

The low level of progress in poverty alleviation in Indonesia is the responsibility of all elements of society. To achieve the realization of the success of the Sustainable Development Goals (SDGs) in 2030, it must be able to be realized. This is not limited to achieving rather than a target but also a need of each country. Through the collaboration of the National Amil Zakat Agency (BAZNAS) and Islamic Financial Institutions (IFI), it has great potential in realizing the goals of the SDGs to eradicate poverty. This type of research is qualitative with descriptive analysis. The results of the study show that Islamic financial institutions can function as potential partners of BAZNAS in providing a zakat collection platform that is easily accessible to the public. With the integration of Islamic financial services, such as internet banking and mobile banking, customers can easily distribute their zakat, infaq, and shadaqah through IFI.
Covid-19 Pandemic as an Event of Force Majeure in Agreements (Case Study of Indonesian Court Decisions)
Authors: Fadlan Mochamad Lailul , Fidhayanti Dwi
Published: November 2024

The legal uncertainty regarding the categorization of the regarding whether or not the Covid-19 pandemic Covid-19 pandemic as a force majeure condition has led to inconsistent interpretations for those directly impacted by the situation. Therefore, considerations can be accepted as a reason for force majeure in agreements need further analysis, both in terms of written law and judicial practice. The objective of this research is to determine the legitimacy of the Covid-19 pandemic as force majeure condition and to describe the basis of the court’s reasoning in deciding whether the pandemic can be accepted as a valid reason for force majeure in contractual agreements. This research adopts a normative juridical methodology, utilizing a statue approach, case approach, and conceptual approach. The findings reveal that the Covid-19 pandemic may be considered as force majeure, provided that the debtor (in the contract) can demonstrate fulfillment of the force majeure criteria as stipulated in Article 1244-1245 of the Indonesian Civil Code, as well as the International Chamber of Commerce’s Force Majeure and Hardship Clauses. In practice, in determining whether the Covid-19 pandemic qualifies as force majeure, the court evaluates whether the following elements are satisfied, the event is unexpected (i.e., the Covid-19 pandemic), the event is beyond the debtor’s control, there is no element of negligence of intent, and there is good faith in the part of the debtor.