bluuebunny/crossref_metadata_2025 huggingface dataset:
Proand anti-inflammatory cytokines in children with various clinical forms of chronic glomerulonephritis
Authors: Beglyarov R O
Published: December 2017

Aim. Study of the level of pro- and anti-inflammatory cytokines, their relationship and changes, depending on the activity of various variants of chronic glomerulonephritis in children. Methods. 104 children with nephrotic form of chronic glomerulonephritis (group 1), 9 children with hematuric form (group 2) and 88 children with mixed form (group 3) were examined. The average age of children was 10.63±3.88 years. The remission was observed in 130 (45.1%), exacerbation - in 158 (54.9%) patients. The concentration of proinflammatory (interleukin-1β, -8, tumor necrosis factor α, interferon γ) and anti-inflammatory cytokines (interleukin-10 and -4) was determined in the blood by ELISA. Results. A significant increase in the levels of interleukin-1β and -8, tumor necrosis factor α, interferon γ was revealed. The index of cytokines in nephrotic and mixed variant was 2.6 standard units, in hematuric form - 2.5 standard units. More pronounced imbalance of pro- and anti-inflammatory cytokines was revealed in nephrotic and mixed forms of chronic glomerulonephritis. Regardless of the form, an increase was revealed in the ratio of interleukin-1β/interleukin-4 (p 0.05), tumor necrosis factor α/interleukin-4 and tumor necrosis factor α/interleukin-10 (p 0.01). Conclusion. Children with different clinical variants of chronic glomerulonephritis were found to have imbalance of cytokines with the shift towards predominance of proinflammatory cytokines; the most pronounced differences were observed in the content of interleukin-1β and tumor necrosis factor α; both in exacerbation and remission phases cytokine index is higher than 1 which is indicative of active inflammatory process.
Study of the influence of medicinal preparations on the indicators of mixed saliva in patients with essential hypertension
Authors: Vavilova T P , Ostrovskaya I G , Yamaletdinova G F , Dukhovskaya N E , Akhmedov G D , Aligishieva Z A
Published: December 2017

Aim. To identify the effect of drugs on the functional state of the salivary glands in patients with essential hypertension. Methods. A total of 38 hypertensive patients were examined. Depending on the prescribed drug therapy, all patients were divided into four groups: group 1 received an angiotensin-converting enzyme inhibitor; group 2 received a beta-blocker; group 3 received a slow calcium channel blocker, group 4 received a statin. For the analysis of salivary glands, the salivation rate was calculated, pH of the mixed saliva and activity of lactate dehydrogenase, alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase were measured. Results. In the mixed saliva of hypertensive patients, the salivation rate decreased in patients taking statins. The pH values of saliva in all groups were within neutral values, from 6.80 to 7.04. The amount of total protein was increased in patients taking angiotensin-converting enzyme inhibitors and statins, and was reduced in patients taking beta-adrenoblockers and slow calcium channel blockers. High activity of lactate dehydrogenase and aspartate aminotransferase was detected in patients taking statins, which indicates activation of anaerobic bacteria and inflammatory processes in the oral cavity. The increased activity of alkaline phosphatase, noted in patients taking beta-adrenoblockers, suggests possible violation of the processes of enamel mineralization. High activity of alkaline phosphatase and aspartate aminotransferase in the mixed saliva of observed patients coincides with the increase of papillary marginal alveolar index up to 27±4.6%, which indicates the development of pathology in the periodontal tissues. Conclusion. In patients receiving statins salivation function was suppressed; increased activity of lactate dehydrogenase and aspartate aminotransferase in the mixed saliva indicates activation of anaerobic microflora and tissue protein breakdown in the oral cavity.
Evaluation of effectiveness of the use of toothpastes in treatment of non-carious teeth diseases
Authors: Alekberova G I , Ostrovskaya U A , Vavilova T P
Published: December 2017

Aim. To assess the effectiveness of the use of therapeutic and prophylactic toothpastes containing hydroxyapatite nanoparticles or sodium fluoride in patients with non-carious lesions. Methods. Mixed saliva was studied in 40 individuals. All subjects were divided into three groups. Group 1 (n=15) used toothpaste №1 containing zinc citrate and sodium fluoride for tooth brushing, group 2 (n=15) brushed teeth with a paste №2 with hydroxyapatite nanoparticles which contained materials removing dental plaque due to antioxidant β-glycyrrhetinic acid possessing anti-inflammatory activity. The control group included 10 subjects with healthy oral cavity. Hyperesthesia of teeth was assessed using Shiff air sensitivity scale, indices of prevalence of tooth hyperesthesia and intensity of tooth hyperesthesia in %, periodontal condition (papillary marginal alveolar index) in % and the oral hygiene score were determined. The activity of lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase (U/l) before and after tooth brushing with toothpastes containing hydroxyapatite particles or sodium fluoride, was also measured. Results. After tooth brushing with both pastes for three months, a decrease of tooth hyperesthesia was observed, as evidenced by the values of Shiff test, index of prevalence of hyperesthesia and intensity of tooth hyperesthesia. Oral hygiene and periodontal state improved. The best effect was observed with a paste №2, containing anti-inflammatory and abrasive components and hydroxyapatite nanoparticles. This is confirmed by a decrease of the activity of lactate dehydrogenase present in anaerobic bacteria, as well as activity of aspartate aminotransferase and alanine aminotransferase, reflecting a decrease of inflammation in the periodontal tissues. Conclusion. Use of toothpastes containing hydroxyapatite nanoparticles or sodium fluoride reduces hyperesthesia of the enamel and inflammation in the periodontium and is accompanied by decreased activity of enzymes in mixed saliva.
Post-hypoxic reaction of astrocytes of the visual cortex in the experiment
Authors: Drozdova G A , Samigullina A F , Nurgaleeva Ye A , Bayburina G A , Sorokin A A
Published: December 2017

Aim. To study the nature of reactive changes in astrocytic glia and oxidative metabolic status in the visual cortex of experimental animals after acute circulatory arrest. Methods. A series of experiments was performed on 47 mature males of noninbred white rats weighing 150-180 g. Under general ethereal anesthesia, a 5-minute anoxia was modelled by intrathoracic clamping of the vascular bundle of the heart followed by resuscitation and observation of the general state dynamics of the animals within 5 weeks after revitalization. Morphometric characteristics of reactive astrogliosis were studied with evaluation of a neurospecific protein (glial fibrillary acidic protein) by immunohistochemistry. The processes of free radical oxidation in brain homogenates were evaluated by determination of products reacting with thiobarbituric acid and by chemiluminescence analysis. The state of antioxidant system in the studied tissues was determined by recording the activity of superoxide dismutase and the level of reduced glutathione. Results. Regarding astroglial link, significant expression of glial fibrillar acidic protein was recorded throughout the observation period with maximum intensification on day 21 of the experiment. In the early periods and during the second week after recovery, the increase of the light sum of iron-induced chemiluminescence was noted, followed by a prolonged accumulation of secondary metabolites of lipid peroxidation. The investigated level of superoxide dismutase significantly increased not only on days 1-3, but also during the second week of the postresuscitation period. When assessing the level of reduced glutathione, a significant increase of its content occured during the first three days after recovery. Conclusion. The revealed activation of a neurospecific protein production with preceding shifts in pro- and antioxidative systems is indicative of hyperreactive character of astrogliosis formed in brain structures against the continuous oxidative stress, disrupting the functioning of neural networks in the visual cortex of experimental animals.
Comparative characteristics of the hemostasis system state during hypothermic and early reactive periods of general freeze injury in rats
Authors: Lycheva N A , Shakhmatov I I , Moskalenko S V
Published: December 2017

Aim. To study the hemostasis system state in rats during hypothermic and post-hypothermic periods. Methods. Male Wistar rats (53 individuals) were used in the study. The animals from the experimental group underwent single immersion cooling in water at a temperature of 5 °C until profound hypothermia was reached, the control group of the animals was placed in water at a temperature of 30 °C. From the animals of the first group, blood was taken immediately after reaching profound hypothermia and from the second group - 24 hours after cooling was stopped. Results. Comparative analysis of the results showed that immediately after the end of a single cold exposure, significant increase in platelet aggregation activity occured, as well as appearance of thrombinemia markers in the bloodstream and inhibition of fibrinolytic system activity. 24 hours after the experimental exposure, these parameters returned to the initial values. When assessing the activity of external and internal ways of coagulation immediately after the termination of cooling, development of hypocoagulation was established, both with routine tests and from thromboelastography. After 24-hour period, hypocoagulation, recorded immediately after reaching the sought rectal temperature, persisted. Thus, after the end of a 24-hour period after cold exposure termination, most of the parameters of hemostatic system that had deviated immediately after the end of the experiment, returned to the normal level. The delayed effect of hypothermia in such cold exposure regimen manifested only by hypocoagulative shift at the initial stages of coagulation. Conclusion. Signs of abnormal hemostasiological blood properties, recorded immediately after the cooling termination, disappear within 24 hours, and only hypocoagulation persists in the blood.
Association of Fat Mass and Obesity-associated Gene (FTO) rs9939609 Variant with Early Onset Obesity among Bataknese and Chinese Children in Indonesia: A Case-control Study
Authors: Lubis Siska Mayasari , Fattah Miswar , Damanik Harun Alrasyid , Batubara Jose Rizal Latief
Published: December 2017

BACKGROUND: Childhood obesity is associated with the risk of adult obesity and obesity-related chronic disease. The fat mass and obesity-associated gene (FTO) rs9939609 variant are of particular interest because of its association with body mass index (BMI) and obesity-related phenotypes. This study was conducted to investigate the association between FTO gene rs9939609 variant with early onset obesity among Bataknese and Chinese children in Medan, Sumatera Utara, Indonesia.METHODS: The case-control study was carried out at 10 elementary schools in Medan. There were 212 children recruited; 56 early onset obesity and 61 control Bataknese and 49 early onset obesity and 46 control Chinese children. This study included a questionnaire, anthropometric measurements, and blood test analysis. rs9939609 polymorphism genotyping was performed using RT-PCR. Logistic regression, odds ratio (OR) and 95% confidence interval (CI) were calculated to determine the risk of obesity associated with the risk alleles, p<0.05 was considered as statistically significant.RESULTS: This study found a significant association between rs9939609 and early onset obesity in Chinese children (p=0.01), but not in Bataknese. The frequency of AA genotype was lower in the early onset obesity than in the normal weight children, while an OR of 0.69 showed that this genotype may protect against weight gaining and that the TT genotype may predispose to obesity.CONCLUSION: We concluded that the FTO gene rs9939609 is associated with early onset obesity in Chinese ethnicity but not in Bataknese.KEYWORDS: pediatric obesity, FTO gene, rs9939609, polymorphism, Indonesia
Telomere in Aging and Age-Related Diseases
Authors: Meiliana Anna , Dewi Nurrani Mustika , Wijaya Andi
Published: December 2017

BACKGROUND: The number of elderly population in the world keep increasing. In their advanced ages, many elderly face years of disability because of multiple chronic diseases, frailty, making them lost their independence. Consequently, this could have impacts on social and economic stability. A huge challenge has been sent for biomedical researchers to compress or at least eliminate this period of disability and increase the health span.CONTENT: Over the past decades, many studies of telomere biology have demonstrated that telomeres and telomere-associated proteins are implicated in human diseases. Accelerated telomere erosion was clearly correlated with a pack of metabolic and inflammatory diseases. Critically short telomeres or the unprotected end, are likely to form telomeric fusion, generating genomic instability, the cornerstone for carcinogenesis. Enlightening how telomeres involved in the mechanisms underlying the diseases’ pathogenesis was expected to uncover new molecular targets for any important diagnosis or therapeutic implications.SUMMARY: Telomere shortening was foreseen as an imporant mechanism to supress tumor by limiting cellular proliferative capacity by regulating senescence check point activation. Many human diseases and carcinogenesis are causally related to defective telomeres, asserting the importance of telomeres sustainment. Thus, telomere length assessment might serve as an important tool for clinical prognostic, diagnostic, monitoring and management.KEYWORDS: telomerase, cellular senescence, aging, cancer
A internacionalização do ensino superior: um desafio para as universidades
Authors: Zanchet Beatriz Maria Boéssio Atrib , Selbach Paula Trindade , Vighi Catia Simone Becker
Published: December 2017

O interesse em compreender como as universidades vêm se movimentando na implantação do processo da internacionalização provocou a pesquisa em que se buscou compreender as concepções e ações presentes nos movimentos de duas universidades do Extremo-Sul do País. Procuramos evidenciar as aproximações e os distanciamentos entre elas a partir dos discursos sobre a implementação desse processo. Por meio da análise dos dados oriundos de seis entrevistas com gestores, percebemos que a concepção de internacionalização passa pela perspectiva dos acordos nacionais e internacionais, incluindo a participação de alunos em programas de mobilidade estudantil com expressivo interesse dos gestores em relação ao significado desse processo mais amplo de internacionalização no contexto do ensino superior. Houve destaque ao estabelecimento de cooperação no contexto “sulino” e ao desenvolvimento regional como resultado da internacionalização. Concluímos que a compreensão dessa complexa temática é frágil no contexto das universidades pesquisadas e que há forte indício da necessidade de potencializar mais ações no sentido da internacionalização.
O trabalho de fim de curso como contributo para a formação inicial de professores: uma análise focada no instituto superior de ciências da educação (ISCED) de Cabinda, Angola
Authors: Canhici Maria Helena , Leite Carlinda , Fernandes Preciosa
Published: December 2017

No artigo expõe-se sobre a opção, no Instituto Superior de Ciências da Educação (ISCED) de Cabinda, por um Trabalho de Fim de Curso (TFC) como contributo para a formação inicial de professores. Recorrendo a entrevistas, no estudo analisam-se as opiniões dos responsáveis da Decania e dos chefes dos departamentos de ensino e investigação. Na opinião dos responsáveis pelo ISCED, o modelo de formação adotado proporciona conhecimentos gerais de conteúdos de ensino e de investigação, embora não forneça conhecimentos específicos relativos a práticas docentes. Considerando a opinião dos entrevistados, embora a opção curricular por um TFC em vez de um estágio com relatório não seja considerada a ideal para a formação de futuros professores, ela permite que os estudantes desenvolvam competências investigativas nos domínios dos estudos que realizam, habilitando-os a um desempenho melhor no curso.
A pedagogia do estético na formação docente: uma proposta de (re)(des)construção de conceitos sobre famílias
Authors: Oliveira Júnior Isaias Batista de
Published: December 2017

Neste texto o objetivo é problematizar o conceito de família ideal e família desestruturada de professores da educação básica da rede pública de ensino. Para atender ao objetivo proposto, traz-se o recorte de uma pesquisa de doutoramento, na qual elaborou-se, desenvolveu-se e aplicou-se uma proposta de formação para 15 docentes da educação básica. A metodologia consistiu na transmissão de obras fílmicas, em um total de oito encontros, cuja temática central era famílias não convencionais. Durante a intervenção aplicamos de forma individual um conjunto de instrumentos para coleta de dados, no entanto, neste artigo enfatizam-se os resultados obtidos mediante aplicação do inventário com ênfase no trabalho de Associação Livre de Palavras (ALP), o qual foi proposto no primeiro e no último encontro. Os dados obtidos foram categorizados com o auxílio do software EVOC e discutidos com base na Teoria das Representações Sociais (TRS), com apoio da Teoria do Núcleo Central (TNC). Concluiu-se que o cinema associado a outras estratégias que problematizem o conceito de família possibilita mobilizar e ressignificar sentidos associados aos conceitos de família ideal e família desestruturada.
Gestão democrática e participação na composição de conselhos municipais de educação no Paraná
Authors: Flach Simone de Fátima , Sakata Kelly Letícia da Silva
Published: December 2017

A partir de pesquisa bibliográfica e análise documental, no presente texto tem-se como objetivo discutir o entendimento e a efetivação da gestão democrática em Conselhos Municipais de Educação no Paraná. Para tanto, apresentam-se discussões a respeito da democracia e as possibilidades de sua efetivação na educação, a forma como a composição e o funcionamento de Conselhos Municipais de Educação colaboram (ou não) para a efetivação do princípio constitucional, e como esta ocorre em um dos municípios pesquisados. Ao final, considera-se que tanto a composição quanto a atuação dos órgãos colegiados são contraditórias, pois, ao mesmo tempo que possibilitam a participação de diferentes segmentos sociais, sofrem interferências políticas locais, as quais limitam a atuação coletiva.
Sobre a capa
Authors: Diersmann Admin Débora
Published: December 2017

Sobre a capa
Adiós a las fojas. Reglas procesales, autos acordados y tramitación electrónica en Chile
Authors: Larroucau Torres Jorge
Published: December 2017

El sentido de implementar una tramitación electrónica en Chile no se limitó a la gestión de las causas judiciales –terminar con los expedientes en papel, ahorrar más espacio en los juzgados y, en general, promover un trabajo eficiente–, sino que dio cuenta de una concepción de la administración de justicia que se aleja de la manera tradicional de entender la tarea judicial como una simple aplicación del derecho. En este artículo, junto con identificar los antecedentes tanto internos como externos de esta reforma procesal, así como los cambios que introdujo en la justicia civil, se analiza una de las aristas más complejas de esta concepción no tradicional de la relación entre justicia y ciudadanía: el rol que le correspondería a la Corte Suprema en la creación de las reglas procesales mediante autos acordados.
The comparison of Polish and Norwegian policy and research on work-life balance – current state of knowledge and future perspectives. Narrative review
Authors: Stańczak Aleksander , Merecz-Kot Dorota , Jacukowicz Aleksandra
Published: December 2017

The sense of work-life balance has an undoubted impact not only on employees’ quality of life and work performance, but also on the functioning of companies. Therefore, efforts to maintain work-life balance are beneficial to workers, employers, authorities and researchers. Poland and Norway are the examples of European countries with different work-life balance policies both on legal and organizational levels. This paper aims to compare legal solutions in two economically different countries and review current research on work-life balance issues therein. Norway is a much richer country, disposing of higher possibilities in supporting citizens. The state, however, guarantees similar solutions in Poland, except for parental leaves system. Polish researchers, unlike Norwegian ones, focus more on the use and the availability of different benefits. Norwegian studies, in turn, show psychological determinants and effects of work-life (im)balance. The authors of this paper also give some suggestions for future research that could help shaping proper family-friendly policies, both in Poland and Norway.
Aktywność stowarzyszeń biegaczy–amatorów w Polsce. Kilka uwag o generowaniu zasobów kapitału społecznego
Authors: Stempień Jakub Ryszard
Published: December 2017

W artykule zostały przedstawione wyniki badania własnego dotyczącego działalności stowarzyszeń biegaczy-amatorów (tzw. klubów biegacza) w Polsce. Badanie zostało wykonane z wykorzystaniem analizy danych zastanych on-line (ang. desk research), obejmując 99 zidentyfikowanych organizacji tego typu. Pomiar uwzględniał aktywność badanych podmiotów w 2014 i 2015 roku. Zebrane dane dotyczą lokalizacji (województwo, wielkość miejscowości), liczby członków oraz rodzajów działań podejmowanych przez kluby biegacza, w układzie ich współpracy z jednostkami samorządu terytorialnego, innymi organizacjami pozarządowymi oraz firmami komercyjnymi. Uzyskane wyniki mogą być interpretowane w perspektywie teorii kapitału społecznego, w ujęciu proponowanym przez Roberta D. Putnama.
Weed management options in transgenic stacked and non transgenic maize (Zea mays) hybrids-A review
Authors: Sivagamy K. , Chinnusamy C. , Parasuraman P.
Published: December 2017

Weeds are generally hardy species having fast growth, deep root system and capable of competing very efficiently with cultivated crops for the available resources and adversely affect the crop growth and yield. Weed management systems that rely on post emergence control assume that crops can tolerate competition for certain periods of time without suffering yield losses. Initial slow growth particularly at early crop growth stages and wider plant spacing of maize crop encourages fast and vigorous growth of weeds. It is of paramount importance that, competition from weeds must be minimized to achieve optimum yield. Among the different weed control methods, chemical method bears many advantages in suppressing weed growth and to get healthy and vigorous crop stand. Non-selective herbicide molecules with a variety of mode of action were discovered, developed and marketed for successful weed control programme.
Effect of mulching on soil and water conservation -A review
Authors: Sharma Rupali , Bhardwaj Sandeep
Published: December 2017

The need to increase food production and improve the quality of our environment has prompted a search for materials to control wind and water erosion. This paper is a review of research and development associated with application, methods, and amounts of mulch types-crop residues, chemical soil stabilizers, and feedlot wastes (manure)-required to control wind erosion. An effective wind erosion control treatment is one that can resist a 38.0 m/s wind as measured at 15.2 m. Mulching has becomes an important practice in modern field production. Mulch paper reduces the application of chemical fertilizer and herbicide, weed control and maintain the land temperature. This article reviews the published research on mulches and discusses the opportunities that they solving the problem in agriculture.
La producción fotográfica escolar de Ezequiel Fernández Santana 100 años después (1915-2015)
Authors: Soto Vázquez José , Pérez Parejo Ramón
Published: December 2017

Recientes estudios han demostrado las interesantes aportaciones de la fotografía escolar al ámbito de la investigación en Historia de la Educación. En este contexto, las fotografías de Ezequiel Fernández Santana, tomadas entre 1915 y 1938, constituyen un hito en la historia de la fotografía escolar de España. Los cristales originales fueron hallados en un vertedero, después fueron restaurados y digitalizados, según los criterios contemporáneos para fondos documentales, así como catalogados para su correcta identificación, cronología, y tema. Su conservación actual permitirá el estudio de la fotografía escolar con fines artísticos y propagandísticos, dado que estos materiales constituyen un ejemplo único en este sentido. El corpus supone un material inédito y exclusivo, no solo por proceder de un mismo fotógrafo, sino también por su cantidad (220 imágenes), su unidad temática, y su perspectiva pedagógica. De  este modo se aúna en su figura el valor de la fotografía tomada in media res por el mismo maestro.

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Contextualización: Idioma Maya Mam

Contextualizador: Rosendo Ordóñez Maldonado

Ministerio de Educación de Guatemala

CH’IN TUMILAL

Matz’el  nikyb’aj  ti’j   tb’inchb’en  tib’lal jaku  onin nimxix ti’j  xpich’b’il   ti’j  tza’n  matzaj b’et  xnaq’tzb’il teitz tx’otx’ kyxol,  xjal.  Atzun  txilen qe  tib’lal  machib’ant   tu’n  Ezequiel Fernández Santana tuj          t-ab’q’iyil  1915 ex 1938, ntq’ama’n  txilen  titz’jleni  qe tib’lal   toj  xnaq’tzb’il  twitz  kytx’otx’   kyxe’cil  amq’   jlajxi  nim  a’.    Nti’taq   okq’0’n  kyipumal  tej   kykanet  tnejil  kyu’n  xjal   toj  jun tenb’il  nyaxix tb’anil,  oktzun  jun aq’untl ti’j  tun tb’aj  b’inchet  ex  tu’n  tkoletqe kyjatzun   okq’o’n  xpich’b’il  ti’j   jatumil itzaj  kanet  ex   ti’   nkyq’ama’n  tuj  ju’jun  anb’il tej  kyb’inchet.    Atzun jun kyb’an  ja’lu  tu’n  tb’aj  q’amet ex tu’n  txiyek’at  tonb’il  ti’j  ju’njun xnaq’tzb’il   ex   tza’n  tu’n  tajb’en  qu’n   tuj   tumilalxix.   Kyaqiltzun   b’ib’il aju  nti’  lo’maj  kyu’n  xjal,  b’ele  tu’ntlaj   taq’anb’en  junx  xjal y  nimxix tajlal   tu’n   tb’aj  nuk’b’et,  ti’j   xnaq’tzb’il   ex tu’n  tel  qniky’  ti’  ntaq’a’n   ju’jun   tib’lal.   Kyjatzun a jun tumilal nkyq’ama’n  tib’lal  twitz  qnab’il   ntzaj qe’ tmij jun tanq’ib’il  xjal

 

Tipumal yol: Ujb’il q’ol  tnab’il xnaq’tzb’il; b’inchab’il; yek’b’il ex xnaq’tzb’il; jaxnaq’tz,  tib’lal
Utilization of Supported Liquid Membrane (SLM) in Separation of Pb(II) by Varying Concentration of Carrier and Feed Solution
Authors: Indarti Dwi , Novitasari Novitasari , Sulistyo Yudi Aris
Published: December 2017

Supported liquid membrane (SLM) was prepared by reacting host material with carrier compounds. Carrier compound was Polyethylene Glycol-400 (PEG-400) that have been used with the variation of concentration 0, 2, 4, and 6%. The effect of its variations in SLM was characterized by FTIR and the performance was examined by transporting feed solution Pb(NO3)2 with variation 1, 5, 10, 15, and 25 ppm for 3 hours in pH 3. FTIR spectra depicted that the increasing concentration of PEG would arise the intensity of typical PEG’s functional groups such as -OH, C-O-C, and CH2-CH2 sp3. The optimum transport Pb(II) was achieved by SLM with 6% PEG. Variation of feed solution concentration showed the main effect in SLM activity. The higher of feed solution concentration would decrease of transport activity. The % extract and % recovery 1 ppm was higher than 25 ppm with 72,5% and 70,27% than 6,1% and 3,59%, respectively.

Keywords: supported liquid membrane, Pb(II), poly ethylene glycol, extraction and recovery, carrier compound
The Odd Harmonious Labeling on Variation of the Double Quadrilateral Windmill Graphs
Authors: Firmansah Fery
Published: December 2017

A Graphis calledif it hasvertices and edqes. The graphis said to be an odd harmonious if there exists an injectionsuch that induced mappingis a bijection and is said to be an odd harmonious labeling of. In this paper, we construct the odd harmonious labeling on variation of the double quadrilateral windmill graph with . Moreover, we also give odd harmonious labeling construction for generalized variation of the double quadrilateral windmill graph withand . Keywords: Odd harmonious labeling, variation, double quadrilteral, windmill graph.
Development Design Labako Batik with Combine Fractal Geometry Dragon Curve and Tobacco Leaf Motif
Authors: Wulandari Eka Yuni , Purnomo Kosala Dwidja , Kamsyakawuni Ahmad
Published: December 2017

Labako Batik is a typical batik Jember, derived from the term "La Bako" is the language of Madura that describes the activities of farmers to plant and process the leaves of tobacco. The resulting motives are inspired by the potential of natural resources in Jember such as tobacco, cocoa, dragon fruit, coffee, bamboo, birds and butterflies. The selection of tobacco leaf pattern because Jember Regency as one of the best tobacco producing cities in Indonesia, so that the form of tobacco leaf becomes the most dominant characteristic in making Batako Labako. In recent years the application of fractal forms in batik began to be popularly known as fractal batik. Fractal batik is batik whose design is made with mathematical formulas done with computer technology. Development of Labako batik motif by generating the pattern of tobacco leaves using L-System and then combining with the fractal geometry of dragon curve that has been modeled, using techniques of geometry transformation in Matlab software. Keywords: labako batik, tobacco leaf, fractal, dragon curve, l-system
ANALISIS PERSEDIAAN BAHAN BAKU PADA AGROINDUSTRI KRIPIK BUAH SANUR DI KABUPATEN MALANG
Authors: Ratih Nineng Puspito , Suwandari Anik , Rondhi M
Published: December 2017

Various fruits can be tranformed into delicious edible foods like chips. That was a basic idea which inspired “Sanur” Fruit Chips Agroinduntry to make chips which based on fruits processing. This agroindustry still performs traditional methods to manage its fruit inventory as raw material. This lead to a fluctuation and uncertainty in inventory stock. The traditional inventory in this agroindustry also caused a bottleneck in production process. The research was aimed to : (1) determine the economic order quantity of fruit chips agroindustry. (2) determine the most efficient re-order point of inventory in “Sanur” Fruit Chips Agroindustry. The research was descriptive and analytical. The key informant was selected purposively based on some criteria. Data was collected by using interview and observation. The result showed that : (1) economic order quantity was more preferable than Lot for Lot and tradional methods. (2) the traditional re-order point method in “Sanur” fruit chips agroindustry was not efficient. It was indicated by the safety stock, the amount of procurement and the inventory of minimum raw materials which showed full uncertain.
ANALISIS PRODUKTIVITAS DAN PENDAPATAN TENAGA KERJA PENYADAP KARET DI KABUPATEN JEMBER
Authors: Harieswantini Retno , Subagja Hariadi , Muksin Muksin
Published: December 2017

Rubber plantation development has proven to be the economic driver of the region with a variety of multiplier effect. East Java is one of the potential areas for rubber plantations development. Rubber production in East Java in 2012 amounted to 6,085 tons. This study aims to determine the factors that influence the labor productivity of rubber tappers and differences in productivity, revenue, revenue contributions. This research was conducted by taking locations in Jember by taking Sumberwadung and Durjo plantations as research objects. Data analysis technique used is multiple linear recreation and different test. The analysis show: Labor productivity in plantation rubber tapper Sumberwadung influenced by the outpouring of hours of work, education and training and the environment and work climate. Labor productivity in plantation rubber tapper Durjo influenced by age, environment and climate and the number of family members.Productivity and revenue between growers and Durjo Sumberwadung no different. Labor income between growers and Durjo different Sumberwadung
TINGKAT MOTIVASI PETANI DALAM BETERNAK SAPI DI KECAMATAN SAMBAS KABUPATEN SAMBAS
Authors: 2017 Harmoko
Published: December 2017

Farmers as cattle ranchers, the impetus for raising cows can provide benefits. In addition to the results from farming, cattle results can be used as a "treasure savings". The presumption treasure savings in rural communities in the form of livestock that can provide benefits when needed at the times when it was needed the money. The purpose of this study to determine the level of motivation of farmers to raise cattle and determine the factors that influence it. The research uses descriptive analytical method that aims to describe the motivation of farmers to raise cattle. Samples taken at random from a group of farmers in the villages in the subdistrict of Sambas. Analysis of data using multiple regression. The results showed that the level of motivation of farmers to raise cattle is very high. Factors that affect the motivation of farmers to raise cattle is attitude. In order for farmers positive attitude, do increase the capacity of farmers through workshops, seminar and workshops themed livestock.
PENGEMBANGAN KAWASAN AGRIBISNIS JAGUNG DAN MANGGA DI KABUPATEN BLORA
Authors: Antriyandarti Ernoiz , Ani Susi Wuri
Published: December 2017

Blora is one of the main producers of corn and mango in Central Java which have highcontribution to the national production. Therefore, Agribusiness Region Development of cornand mango in Blora is very important to stimulate economy growth based on regional potencyinvolved by all actors of agribusiness such as government, farmer, and private sector in Blora.The objective of this research is to determine comparative advantage of corn and mango in Blora and to formulate how to develop those commodities. This study applied farming analysis and Policy Analysis Matrix (PAM). The result of the study show that agribusiness of corn and mangoare profitable and there are not any diseconomies resulted from those agribusiness activites.Therefore, agribusiness of those commodities can be developed further.
NO ASSOCIATION OF RECURRENT RESPIRATORY PAPILLOMATOSIS AGGRESSIVENESS AND HUMAN PAPILLOMAVIRUS TYPE 6 AND 11
Authors: Perdana Rizka Fathoni , Herawati Sri , Suroso Bakti , Aksono Eduardus Bimo
Published: December 2017

Recurrent Respiratory Papillomatosis (RRP) is the most common benign neoplasm of the larynx among children as a result of HPV infection mainly type 6 and 11. RRP is still considered as serious problem since papilloma in the airway can cause hoarseness and obstruction which later described as aggressive and non aggressive types. Patients underwent multiple surgeries to keep airway patency and in order to communicate vocally. Previous studies reported that HPV-11 was associated with a more aggressive disease course. This study aim is to determine the association of RRP aggressiveness with HPV-6 and 11. Papilloma specimens were taken from patients who underwent surgical treatment of RRP patients and subjected HPV typing. All 17 patients with completed data and epidemiologic questionaires were defined for their staging to disease severity. Informations in the database were analyzed to identity statistically significant relationship with HPV type and knowing the HPV type is to predict the disease course. 17 patients RRP (12 males and 5 females) with age at onset 3,15 + 2,28 years and age at diagnosis 3,81 + 2,51 years. Surgery was performed 2,71 ± 1,16 times per year and 9 patients treated more than 3 surgeries per year. 10 patients had distal papilloma and 11 patients had tracheotomy. Agrressive disease was show found in 14 patients among 17 patients. HPV-11 was detected in 10 patients, HPV-6 was detected in 7 patients. According to the statisitcal analysis (Chi square test), there is no relationship between HPV type and disease aggressiveness. HPV-6 and 11 are not the only cause that affect the aggressiveness of Recurrent Respiratory Papillomatosis.
INTEGRATING THE ROLES OF STAKEHOLDERS IN PREVENTING THE HIV/AIDS TRANSMISSION IN EAST JAVA, INDONESIA
Authors: Koesbardiati Toetik , Kinasih Sri Endah , Mas’udah Siti
Published: December 2017

HIV/AIDS prevention is very important and absolutely necessary. HIV transmission is now entering a fairly alarming level, in which people with HIV/AIDS in certain subpopulations are emerging. Special steps and resources are thus needed to cope with the condition. There are some phenomena potentially encourage HIV transmissions, such as the increasingly common free sex, homosexuality, the use of unsafe and unsterile syringes in narcotics consumption, commercial sex workers and various high-risk sexual activities. One of the crucial concerns that arises when sending prostitutes back to their hometowns without any coordinated and holistic mechanism is that the prostitutes may cause the spreading of HIV/AIDS in their hometowns. The research objective is to provide the material (input) how the prostitutes themselves may cause the spreading of HIV/AIDS. The research employed descriptive method with a qualitative approach. The results showed that the implementation and the role division in the closure have been highly coordinated and holistic. The leading sector in the role division is the Social Welfare epartment of the Government in Surabaya. In terms of health aspects for the former prostitutes sent back to their hometowns, there has been no policies related to medical screening designed to identify the disease early. Screening is very important for early diagnosis during the post-closure phase. The screening mechanism is that the Provincial Health Department has to optimize the monitoring, coordination, cooperation, agreements and partnerships with stakeholders such as the Local Health Department and the National/Provincial/Distric AIDS Commission, NGOs that are concerned with the problems of HIV-AIDS, international organizations, professional organizations, community leaders, religious leaders and universities.
AN EVALUATION STUDY OF ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA) USING RECOMBINANT PROTEIN GRA1 FOR DETECTION OF IgG ANTIBODIES AGAINTS TOXOPLASMA GONDII INFECTIONS
Authors: Muflikhah Nina Difla , Artama Wayan Tunas
Published: December 2017

Toxoplasmosis is an infectious disease caused by Toxoplasma gondii, an intracellular protozoan parasite that live inside the cells of the reticulo endothelial and parenchymal cells of human and animals (mammals and birds). Some cases of toxoplasmosis usually have no symptoms, but in any cases caused severe symptoms, such as hydrocephalus, microcephalus, intracranial calcification, retinal damage, brain abscess, mental retardation, lymphadenopathy, and others. Its severe symptoms usually showed a long time after first exposure, except symptoms showed by congenital transmission caused by infected mother. Early diagnosis is important to prevent the illness but methods for toxoplasmosis screening are still too expensive for developing country. Enzyme-linked immunosorbent assay (ELISA) allow the testing of a large number samples within short time frame and based on antibody or antigen detection. This study aimed to know the sensitivity and specificity of recombinat protein GRA1 as antigen using ELISA methods. We tested the sensitivity and spesificity of GRA1 protein as antigen in ELISA methods to diagnose toxoplasmosis and compared with ELISA Kit Commercial. Reliable laboratory testing is important to detect Toxoplasma gondii infection, and focused to improving the low cost and easy-to-use diagnostic instrument. Seventy sera collected and tested using both indirect ELISA, commercial ELISA kit and GRA1 protein coated as antigen. Fourty eight and fifty one samples showed positive IgG antibody result of ELISA-GRA1 and ELISA kit. Negative sample tested by ELISA-GRA1 was 22 samples and 19 sample tested by ELISA Kit. The sensitivity and specificity of GRA1-based on ELISA were 100% and 86.36%, positive prediction value (ppv) was 94.11%. These data indicate that the recombinant protein GRA1 is a highly immunogenic protein in human toxoplasmosis and become a promising marker for the screening of toxoplasmosis.
Cirurgia de alta frequência no colo uterino: análise dos fatores de recidiva
Authors: Arruda Pâmela Mendes , Coelho Raquel Autran , Rebouças Karinne Cisne Fernandes , Tavares Amanda Zélia de Sousa , Lima Gabriele Santana Sá
Published: December 2017

Introdução: o tratamento da lesão intraepitelial de alto grau do colo uterino (LIEAG), precursora de carcinoma invasor, é realizado preferencialmente por conização. Objetivo: correlacionar a evolução clínica de pacientes acometidas por LIEAG submetidas a conização com dados do espécime cirúrgico e com fatores epidemiológicos. Metodologia: estudo retrospectivo de 60 pacientes submetidas a conização por cirurgia de alta frequência (CAF) de 2012 a 2015, cujo acompanhamento da evolução foi realizado com exame citopatológico e colposcópico. Foram excluídas as pacientes gestantes, imunossuprimidas, que tinham se submetido apenas à biópsia, conização a frio ou histerectomia e resultados anatomopatológicos sem descrição das margens cirúrgicas. Resultados: a medida da altura da peça variou de 0,5 a 3,3 cm. Dez pacientes apresentaram recidiva. Não houve influência de idade ou fumo e contracepção. Houve diferença significativa entre a profundidade da peça e a ocorrência de margens comprometidas.Visando diminuir as complicações da conização, observa-se uma tendência a redução do tamanho das peças. Este estudo mostrou aumento do risco de margens comprometidas em tais situações, sem repercussão na recidiva de doença. Conclusão: a ocorrência de margens comprometidas foi maior em espécimes menores de conização, mas esse tamanho não influenciou no risco de recidiva de lesão induzida pelo HPV (Papiloma Vírus Humano).
Tratamento endovascular de estenose de artéria renal em rim transplantado
Authors: Albuquerque Francisca Jovita de Oliveira Veras , Pereira Rafael Augusto Oliveira , Macedo Carolina Teles de , Andrade Filho João Edison de , Linhares Filho Frederico Augusto de Carvalho , Leão Filho Carmelo Silveira Carneiro
Published: December 2017

Introdução: a estenose de artéria renal transplantada (EART) é a complicação vascular mais frequente do transplante renal. O diagnóstico é realizado através da arteriografia e o tratamento consiste na angioplastia transluminal percutânea (ATP). Objetivo: avaliar o sucesso clínico, a patência primária e secundária da ATP, bem como a sobrevida dos pacientes após o tratamento endovascular. Métodos: análise retrospectiva dos pacientes com EART tratados por ATP no período de janeiro de 2008 a dezembro de 2016 no Hospital Universitário Walter Cantídio. Resultados: 28 pacientes foram tratados por EART através do método endovascular. A pressão diastólica reduziu de 91,62 mmHg para 76 mmHg, em média, após 6 meses do tratamento (p<0,05). Observou-se uma redução nos níveis de creatinina após 3, 6 e 24 meses da angioplastia (p=0,005). As taxas de patência primária em 1, 3, 6, 12 e 24 meses foram de 89,3% +/- 5,8%, 85,6% +/- 6,7%, 81,8% +/- 7,4%, 78,1% +/-7,9% e 68,9% +/- 9,3%, respectivamente. A taxa de patência secundária foi de 100%. A taxa de sobrevida em 1, 3, 6, 12 e 24 meses foi de 96,4% +/- 3,5%, 96,4% +/-3,5%, 92,6% +/- 5,1%, 92,6% +/- 5,1% e 83,8% +/- 7,5%, respectivamente. Conclusão: o tratamento endovascular de EART apresenta boas taxas de patências primária e secundária e é efetivo em restaurar e manter a função renal em dois anos.
Associação de transfusão de concentrado de hemácias (CH) e enterocolite necrosante (ECN): relato de caso
Authors: Otsutsumi Junior Jun , Fontenele Maria Marcia Farias Trajano , Lavor Maria Francielze Holanda , Brunetta Denise Menezes
Published: December 2017

A Enterocolite necrosante é uma síndrome clínicopatológica caracterizada por sinais e sintomas gastrintestinais e sistêmicos. De etiologia incerta, atinge um em cada 1.000 nascidos vivos. Alguns eventos levam à suspeita da síndrome, a qual pode estar associada à transfusão de hemácias. Objetivou-se relatar o caso de um recém-nascido prematuro que apresentou sinais de enterocolite necrosante após uma transfusão sanguínea com concentrado de hemácias. Recém-nascido, internado em uma Maternidade Escola de Fortaleza, Ceará, apresentava bom desenvolvimento e anemia, com hemoglobina 9,34 e hematócrito 30,1, sendo indicada transfusão. Na primeira transfusão, não apresentou reação clínica pós-transfusão; com 51 dias de vida, devido a outro quadro de anemia, foi indicada nova transfusão, apresentando hipoatividade, distensão abdominal e dois episódios de queda de saturação; após 66 dias, houve nova indicação para transfusão, a qual após infusão de 5,1ml evoluiu com novo episódio de taquidispneia, distensão abdominal e hiposaturação. O caso demonstrou evidência e clareza conforme achados na literatura. Observou-se que o uso da imagem como exame complementar para o diagnóstico identifica precocemente os achados da doença.
Five Phases Music Therapy (FPMT) in Chinese Medicine: Fundamentals and Application
Authors: Zhang Hui , Lai Han
Published: December 2017

Music therapy has served as complementary and alternative medicine for various neurological disorders. Five Phases Music Therapy (FPMT) employs the theory of five phases and five music scales or tones (宫Gong (do), 商Shang (ri), 角Jue (mi), 徵Zhi (so) and 羽Yu (la)) to analyze and treat mind-body illness. In Chinese Medicine (CM), the five music scales are used to connect the human body and the universe, interpret personalities and constitution and analyze the influences of climatic changes on health. FPMT has a self-contained theory and routine of practice application. Large amounts of clinical and fundamental reports have been available and clinical benefits have been obtained. However more systemic clinic research esp. evidence-based and random controlled trials must be performed to validate and optimize its routines and biological and neurological mechanism must be further explored. It’s reasonable to believe that the effective music therapy will attract more attention from the world outside China with the introduction of FPMT.
Democracia e responsabilidade: breve análise dos instrumentos de responsabilização política nas democracias contemporâneas
Authors: Iensue Geziela , Sgarbossa Luis Fernando
Published: December 2017

A temática da responsabilidade política dos governantes é um problema clássico da teoria política e da teoria constitucional. Não obstante, continua a suscitar questões importantes tanto para a análise teórica quanto no que diz respeito a situações práticas, especialmente em termos de adoção das instituições adequadas para promover a responsabilidade dos governantes sem incorrer em excessiva instabilidade ou até mesmo desbordar em eventual crise de governabilidade. O presente artigo pretende examinar alguns institutos cujo escopo é a promoção da responsabilidade governamental, evidenciando seus benefícios e eventuais custos em termos de estabilidade governamental. O trabalho evidenciará a existência de uma relação inversa entre responsabilidade e estabilidade governamental, e sustentará a dificuldade em se encontrar, até o momento, um modelo que promova a responsabilidade no maior grau possível com os menores custos em termos de estabilidade e governabilidade, e vice-versa.