bluuebunny/crossref_metadata_2025 huggingface dataset:
Immediate Psychosocial Impact on Healthcare Workers During COVID-19 Pandemic in China: A Systematic Review and Meta-Analysis
Authors: Dong Fei , Liu Hong-liang , Yang Ming , Lu Chun-li , Dai Ning , Zhang Ying , Robinson Nicola , Liu Jian-ping
Published: May 2021

Objectives: The corona virus disease-2019 (COVID-19) pandemic spread globally, and we aimed to investigate the psychosocial impact on healthcare workers (HWs) in China during the pandemic.

Methods: In this systematic review and meta-analysis, we searched seven electronic databases for cross-sectional studies on psychosocial impact on HWs in relation to COVID-19 from January 1, 2020 to October 7, 2020. We included primary studies involving Chinese HWs during the pandemic, and data were extracted from the published articles. Our primary outcome was prevalence of anxiety, depression, and stress disorders. We pooled prevalence value with their 95% confidence interval using random effect models and assessed study quality on the basis of an 11-item checklist recommended by the Agency for Healthcare Research and Quality. The study protocol was registered in PROSPERO (CRD42020195843).

Results: We identified 25 articles comprising a total of 30,841 completed questionnaires and 22 studies for meta-analysis. The prevalence of anxiety, depression, and stress disorders was 34.4% (29.5–39.4%), 31.1% (24.5–37.7%), and 29.1% (24.3–33.8%) for HWs. The pooled prevalence of anxiety disorders for HWs from late January to early February was 46.4% (42.9–49.9%), significantly higher than those in mid-term February (28.0%, 23.9–32.1%) and after late February (27.6%, 16.0–39.2%). The pooled prevalence of depression disorders for HWs from late January to early February was 46.5% (38.8–54.2%), significantly higher than those in mid-term February (27.1%, 19.8–34.5%) and after late February (32.9%, 16.2–49.5%). HWs working in Hubei Province had a higher prevalence of anxiety (37.9 vs. 30.8%) and a lower prevalence of depression (27.5 vs. 34.7%) than those working in other regions. Nurses had a higher prevalence of anxiety (44.1 vs. 29.0%) and depression (34.1 vs. 29.2%) than other HWs.

Conclusions: About one-third of HWs in China suffered anxiety, depression, and stress at the early epidemic of COVID-19. HWs in Hubei Province, especially nurses, had a higher prevalence of psychological disorders. During the pandemic, a negative psychological state may persist in a proportion of Chinese HWs, fluctuating with the control of the pandemic. The long-term impact should continue to be observed. Attention should be paid to HWs for their psychological impact due to the pandemic.

Systematic Review Registration: The study protocol was registered with PROSPERO (CRD42020195843).
Design and Validation of an Observational System for Penalty Kick Analysis in Football (OSPAF)
Authors: Pinheiro Guilherme de Sousa , Nascimento Vitor Bertoli , Dicks Matt , Costa Varley Teoldo , Lames Martin
Published: May 2021

The analysis of penalty kick has played an important role in performance analysis. The study aims are to get formal feedback on the relevance of variables for penalty kick analysis, to design and validate an observational system; and to assess experts’ opinion on the optimum video footage in penalty kick analysis. A structured development process was adopted for content validity, reliability and agreement on video usage. All observational variables included in OSPAF showed Aiken’s V values above the cut-off (for 5-scale V> 0.64; for 2-scale = V > 0.75; p < 0.05). Cohen’s Kappa resulted in mean intra- and inter-rater reliability values of 0.90 and 0.86, respectively. It is recommended to combine at least three different viewing angles (V = 0.90; p = 0.006) with standardization of video quality (V = 0.95; p = 0.006). Changing the viewing angles may influence the observer perception (V = 0.86; p = 0.006). The aerial and pitch-level viewing angle behind the penalty taker and pitch-level viewing angle behind the goalkeeper were indicated as most appropriate for observational analysis (V = 0.97; p = 0.01). The OSPAF met all requirements of instrument validation. It may be recommended as basis of future observational systems on penalty kicks.
Monitoring and Behavior of Biomotor Skills in Futsal Athletes During a Season
Authors: Stochi de Oliveira Ricardo , Borin João Paulo
Published: May 2021

Futsal is a sport that presents alternation of high and low intensity moments, which lacks investigations regarding the effects of the organization of the training load on biomotor skills. In this sense, this study aims to verify the monitoring of the training load throughout the season and the behavior of biomotor skills in futsal athletes. Twelve futsal athletes (24.5 ± 4.9 years, 1.79 ± 0.6 m, 72.4 ± 9.4 kg, and 9.4 ± 4.3% fat) from the adult category who competed in the first division of the Paulista championship participated in the study. Throughout the season the internal training load (ITL) was calculated, through the relationship between volume (minutes) and the rate of perceived exertion (RPE), monotony, and training strain. The training periods were divided into: preparatory, competitive and competitive II, for a total of four moments of evaluation: M1: at the beginning of the preparatory period; M2: 5th week, at the end of the preparatory period; M3: 13th week, in the middle of the competitive period; and M4: at the start of the competitive period II. The tests used were: (i) Power of lower limbs: counter movement jump (CMJ); (ii) Displacement speed, over the 10-meter distance (V10m); and (iii) Aerobic power, by the Carminatti test (T-CAR). The variables analyzed were compared at the different moments of evaluation, normally distributed variables (Volume, S-RPE, strain, and monotony) were analyzed using the ANOVA ONE-WAY variance test followed by the Tukey. Variables that did not show normality (lower limb power, speed, and aerobic power) were compared using the Friedman test followed by Dunn's multiple comparisons test and was presented by median and interquartile interval. The significance value adopted was p < 0.05. A significant improvement (p < 0.05) was observed in the power of lower limbs from M1 (37.5 ± 5.5 cm) to M3 (40.8 ± 5.7 cm), from M2 (38.9 ± 5.5 cm) to M3 (40.8 ± 5.7 cm), and from M1 (37.5 ± 5.5 cm) to M4 (40.2 ± 5.4 cm). Aerobic power showed a significant increase (p < 0.05) from M1 (12.1 ± 0.7 km/h) to M3 (12.7 ± 7 km/h) and from M1 (12.1 ± 0.7 km/h) to M4 (12.73 ± 1.04 km/h). The internal training load showed a difference between competitive I and II in relation to the preparatory period (p < 0.05). In conclusion, the proposed training organization was sufficient to improve the power of the lower limbs and the aerobic power.
Psychological Well-Being in Chinese College Students During the COVID-19 Pandemic: Roles of Resilience and Environmental Stress
Authors: Tan Yuanfa , Huang Chienchung , Geng Yun , Cheung Shannon P. , Zhang Shuyan
Published: May 2021

Psychological well-being is an important indicator of well-being and has been found to be associated with a multitude of positive life outcomes. Using data collected from 1,871 Chinese college students from September 23 to October 5, 2020, this study examined students' psychological well-being during the COVID-19 pandemic and investigated how resilience and pandemic-related environmental stress may affect psychological well-being. Results showed that resilience had strong positive effects on psychological well-being during the pandemic. Meanwhile, environmental stress had a moderate effect and marginally reduced psychological well-being. The magnitudes of the estimates suggested that increasing resilience can effectively buffer the negative effect of environmental stress on psychological well-being.
What Still Needs to be Noted: Pseudo-Clefts in the Academic Discourse of Applied Linguistics
Authors: Zhou Hui , Chen Ming
Published: May 2021

Pseudo-clefts are the building blocks of coherent discourse progression and serve as a rhetorical toolkit to construct an authorial stance in the academic discourse. Despite an increasing interest in grammatical constructions in the academic discourse, researchers have not treated pseudo-clefts in much detail. This paper explores the features of pseudo-clefts in the corpus of academic discourse in the field of applied linguistics. Here, we take the textual and the interpersonal perspectives, focusing on the use of pseudo-clefts in terms of their distribution in generic structure, discourse functions with reference to clefted constituents, and evaluative meaning. The results show that pseudo-clefts were more frequently used in “Results and Discussion” and Literature Review, performing the functions such as the specification of key terms, generalization of the literature, the description and explanation of findings, etc. They are facilitative in creating information gaps and establishing a logic-semantic expansive relationship between the clauses. The findings also suggest that the pseudo-clefts are evaluative devices and are involved in the construction of authorial identities.
Social Isolation During COVID-19 Pandemic. Perceived Stress and Containment Measures Compliance Among Polish and Italian Residents
Authors: Grabowski Jakub , Stepien Joanna , Waszak Przemyslaw , Michalski Tomasz , Meloni Roberta , Grabkowska Maja , Macul Aleksandra , Rojek Jakub , Lorettu Liliana , Sagan Iwona , Bidzan Leszek
Published: May 2021

Background

In this study, we analyze the association of social isolation in the first phase of the pandemic with perceived stress among residents of Poland and Italy with a look at how these populations adjust to and comply with implemented regulations, guidelines, and restrictions.

Materials and Methods

Internet survey with Perceived Stress Scale (PSS-10) and questions regarding mobility patterns, attitude, and propensity to adjust toward the implemented measures and current health condition was made among Polish and Italian residents (Cronbach’s alpha 0.86 and 0.79, respectively). The sample size was 7,108 (6,169 completed questionnaires in Poland and 939 in Italy).

Results

The Polish group had a higher stress level than the Italian group (mean PSS-10 total score 22,14 vs 17,01, respectively;p< 0.01). There was a greater prevalence of chronic diseases among Polish respondents. Italian subjects expressed more concern about their health, as well as about their future employment. Italian subjects did not comply with suggested restrictions as much as Polish subjects and were less eager to restrain from their usual activities (social, physical, and religious), which were more often perceived as “most needed matters” in Italian than in Polish residents.

Conclusion

Higher activity level was found to be correlated with lower perceived stress, but the causality is unclear. Difference in adherence to restrictions between Polish and Italian residents suggests that introducing similar lockdown policies worldwide may not be as beneficial as expected. However, due to the applied method of convenience sampling and uneven study groups, one should be careful with generalizing these results.
Equal Opportunity Interference: Both L1 and L2 Influence L3 Morpho-Syntactic Processing
Authors: Abbas Nawras , Degani Tamar , Prior Anat
Published: May 2021

We investigated cross-language influences from the first (L1) and second (L2) languages in third (L3) language processing, to examine how order of acquisition and proficiency modulate the degree of cross-language influences, and whether these cross-language influences manifest differently in online and offline measures of L3 processing. The study focused on morpho-syntactic processing of English as an L3 among Arabic-Hebrew-English university student trilinguals (n = 44). Importantly, both L1 (Arabic) and L2 (Hebrew) of participants are typologically distant from L3 (English), which allows overcoming confounds of previous research. Performance of trilinguals was compared to that of native English monolingual controls (n = 37). To investigate the source of cross-language influences, critical stimuli were ungrammatical sentences in English, which when translated could be grammatical in L1, in L2 or in both. Thus, the L3 morpho-syntactic structures included in the study were a mismatch with L1, a mismatch with L2, a Double mismatch, with both L1 and L2, or a no mismatch condition. Participants read the English sentences while their eye-movements were recorded (online measure), and they also performed grammaticality judgments following each sentence (offline measure). Across both measures, cross-language influences were assessed by comparing the performance of the trilinguals in each of the critical interference conditions to the no-interference condition, and by comparing their performance to that of the monolingual controls. L1 interference was evident in first pass sentence reading, and marginally in offline grammaticality judgment, and L2 interference was robust across second pass reading and grammaticality judgments. These results suggest that either L1 or the L2 can be the source of cross-language influences in L3 processing, but with different time-courses. The findings highlight the difference between online and offline measures of performance: processing language in real-time reflects mainly automatic activation of morpho-syntactic structures, whereas offline judgments might also involve strategic and meta-linguistic decision making. Together, the findings show that during L3 processing, trilinguals have access to all previously acquired linguistic knowledge, and that the multilingual language system is fully interactive.
Sinisan Protects Primary Hippocampal Neurons Against Corticosterone by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway
Authors: Zhang Mingjia , Zhang Yi , Sun Haitao , Ni Hui , Sun Jialing , Yang Xuemei , Chen Weicong , Zhao Wenting , Zhong Xiaodan , He Chunyu , Ao Haiqing , He Songqi
Published: May 2021

Objective: Corticosterone causes significant neurotoxicity in primary hippocampal neurons which is associated with depression. Dysfunctional autophagy is implicated in cognitive impairment and depressive-like behavior. The traditional Chinese medicine Sinisan (SNS) is highly effective in clinical treatment of depression. However, the molecular mechanisms underlying therapeutic effects of SNS are unknown.

Purpose: The aim of this study was to elucidate the protective effect of SNS and the underlying mechanisms against corticosterone-induced neuronal damage.

Study Design: The effects of serum derived from rats containing SNS (or untreated controls) on the expression of autophagy-related molecules in primary rat hippocampal neurons exposed to different concentrations of corticosterone for different intervals were explored.

Methods: CCK-8 assay, LDH assay were used to analyze cell viability and LDH activity. Western blot, qRT-PCR, and immunofluorescence assays were used to determine protein and mRNA expression levels of molecules such as LC3, p62, Beclin1, ULK1, PI3K, p-PI3K, Akt p-Akt, mTOR, p-mTOR, p70S6, p-p70S6, 4ebp1 and p-4ebp1.

Results: Corticosterone induced a dose- and time-dependent reduction in cellular viability. Moreover, corticosterone (100–400 μM) treatment for 24 h increased LC3-II/LC3-I protein ratio, increased Beclin1 and ULK1 protein expression levels, and decreased p62, PI3K, p-PI3K, p-Akt, p-mTOR, p-p70S6, and p-4ebp1 protein expression levels. Notably, SNS-containing serum reversed corticosterone-induced reduction of neuronal viability, and increased p62, PI3K, p-Akt, p-mTOR, p-p70S6, and p-4ebp1 protein and mRNA expression levels. In addition, SNS-containing serum decreased LC3-II/LC3-I protein ratio, and downregulated Beclin1, and ULK1 protein and mRNA expression in primary hippocampal neurons.

Conclusion: SNS protects primary hippocampal neurons against corticosterone-induced neurotoxicity by preventing excessive autophagy through activation of PI3K/AKT/mTOR pathway.
The Differential Impact of Lockdown Measures Upon Migrant and Female Psychiatric Patients – A Cross-Sectional Survey in a Psychiatric Hospital in Berlin, Germany
Authors: Moran James K. , Bretz Joachim , Winkler Johanna , Gutwinski Stefan , Brandl Eva J. , Schouler-Ocak Meryam
Published: May 2021

The COVID-19 pandemic could have major effects on already vulnerable individuals with psychiatric disorders. It is important to assess how different patient groups respond to stress related to the pandemic, and what additional factors influence it, including family-related stress, migration background, and sex. We conducted a survey in a sample of 294 psychiatric patients in a large outpatient clinic in Berlin, measuring level of distress in relation to COVID-19 lockdown as well as family-related distress. We also measured potential influencing factors such as media consumption and medical support. In the migration background group, we found that women had more lockdown related psychological distress than men. This was not apparent in those patients with a German background. We found that females were more strongly affected by family-related distress, particularly those with a migration background. People with PTSD were most strongly affected by family-related distress, whereas people with psychotic disorders and addiction reported the least distress. There were no effects of media consumption. There were no differences in ability to abide by the lockdown related restrictions across diagnoses. Our results support earlier findings on differential vulnerability of diagnostic groups to these stressors. Thus, clinicians can optimize treatment by taking family-related stressors into account particularly for females and people with a migrant background.
Improvements on Clinical Status of Adolescents With Anorexia Nervosa in Inpatient and Day Hospital Treatment: A Retrospective Pilot Study
Authors: Zanna Valeria , Cinelli Giulia , Criscuolo Michela , Caramadre Anna Maria , Castiglioni Maria Chiara , Chianello Ilenia , Marchili Maria Rosaria , Casamento Tumeo Chiara , Guolo Stefano , Tozzi Alberto Eugenio , Vicari Stefano
Published: May 2021

Introduction: Medical and psychiatric complications and treatment compliance are important considerations in determining the treatment program for patients with severe anorexia nervosa (AN). Clinical practice guidelines agree that an outpatient program is the first choice for the treatment of most eating disorders, but vary in supporting these programs for AN. However, inpatient care is known to be costly and the risk of relapse and readmission is high. This pilot study aimed to describe the first data on an Italian partial hospitalization care program for AN adolescents [high-level care treatment (HLCT)], evaluating its impact on patients' clinical status, average hospitalization time, and the hospital costs compared to inpatient treatment (IP).

Methods: For this retrospective pilot study, we have selected a group of 34 females with AN aged 11–18 years, divided between those who followed inpatient treatment and those who received HLCT treatment; they were matched for age and severity. We investigated the differences in treatment and outcomes between the two groups in terms of heart rate, length of treatment, weight gain, psychological characteristics, and hospital costs. Statistics for non-parametric distributions were used to compare the two groups.

Results: No differences between the two groups were found at admission. At discharge, patients in the HLCT group presented a lower number of in-hospital treatment days, a higher increase of weight, and a significant improvement in outcomes compared to the inpatient group. No significant differences were found in heart rate and hospital costs.

Conclusions: This study represents a first comparison between inpatient care and the HLCT treatment program, which suggests that day hospital treatment could represent a meeting point between inpatient and outpatient treatment, combining the merits of both forms of treatment. Further studies are needed in order to better investigate the different treatment programs for severe AN in adolescence.
The COVID-19 Family Stressor Scale: Validation and Measurement Invariance in Female and Male Caregivers
Authors: Prime Heather , Wade Mark , May Shealyn S. , Jenkins Jennifer M. , Browne Dillon T.
Published: May 2021

The COVID-19 pandemic has raised significant concerns regarding the effect of social disruptions on parental mental health, family well-being, and children's adjustment. Due to the pace of the pandemic, measures of pandemic-related disruption have not been subject to rigorous empirical validation. To address this gap, a multi-national sample (United Kingdom, 76%; United States, 19%; Canada, 4%, and Australia, 1%) of 372 female caregivers and 158 male caregivers of 5–18-year-old children was recruited online. Participants completed a survey including a 25-item scale indexing disruption in finances, basic needs, personal and family welfare, career/education, household responsibilities, and family relationships related to the pandemic. An exploratory factor analysis yielded an optimal three-factor solution: factors included Income Stress (five items related to income, debt, and job loss; loadings ranged from 0.57 to 0.91), Family Stress (seven items related to family altercations and child management; loadings from 0.57 to 0.87), and Chaos Stress (four items related to access to supplies, crowded shopping areas, news coverage; loadings from 0.53 to 0.70). Multiple-group confirmatory factor analysis demonstrated measurement invariance of each factor across female and male caregivers, indicating that factor structure, loadings, and thresholds were equivalent across groups. Composites reflective of each factor were computed, and Mann-WhitneyUtests indicated that female caregivers consistently scored higher than male caregivers on COVID-19 stressors related to income, family, and chaos. Finally, concurrent validity was demonstrated by significant bivariate correlations between each scale and caregiver, family, and child outcomes, respectively. This demonstrates the validity of the COVID-19 Family Stressor Scale for use with female and male caregivers in family-based research. The current sample was predominantly White-European, married/common-law, and had at least some post-secondary education. Additional sampling and validation efforts are required across diverse ethnic/racial and socioeconomic groups.
Mental Health Outcomes of Healthcare Providers During COVID-19 Pandemic in Saudi Arabia: A Cross-Sectional Study
Authors: Alhurishi Sultana A. , Almutairi Khalid M. , Vinluan Jason M. , Aboshaiqah Ahmad E. , Marie Mohammed A.
Published: May 2021

Objective: In this descriptive cross-sectional study we aimed, to assess the level of depression, anxiety, insomnia and distress symptoms experienced by healthcare providers during the COVID-19 pandemic in Saudi Arabia.

Methods: All healthcare providers currently working in different hospitals were invited to participate in this study. Data gathering started in March 2020 to May 2020. The participants answered a five-part questionnaire which includes demographic data, a 9-item Patient Health Questionnaire, a 7-item Generalized Anxiety Disorder, a 7-item Insomnia Severity Index, and a 22-item Impact of Event Scale-Revised, which assess the level of depression, anxiety, insomnia, and distress.

Results: Out of 200 healthcare providers, 40% were males. 52% were aged 31–40 years old, 61% were married. The majority of the participants were Saudi nationals (84%), 74% were nurses, 11% were physicians and 15% were other healthcare providers. More than half of the participants worked as front-liners (57%). Overall, 73, 69, 62, and 83% of all healthcare providers reported symptoms of depression, anxiety, insomnia, and distress, respectively. The analysis showed severe symptoms level of depression for physicians and nurses was 35% and 20% (p < 0.05), respectively. Only three of the independent variables made a unique contribution to the model (gender, profession, and working position) (p < 0.05).

Conclusion: COVID-19 pandemic has a significant impact on the mental health of healthcare providers in Saudi Arabia. Female nurses and healthcare providers working in the frontline who were directly treating patients with COVID-19 are at increased risk of severe depression, anxiety and distress.
IMPAACT 2016: Operationalizing HIV Intervention Adaptations to Inform the Science and Outcomes of Implementation
Authors: Libous Jennifer L. , Montañez Nicole A. , Dow Dorothy E. , Kapetanovic Suad , Buckley Janice , Kakhu Tebogo Jacqueline , Kamthunzi Portia , Maliwichi Limbika A. , Vhembo Tichaona , Chawana Tariro Dianah , Nematadzira Teacler , Donenberg Geri R.
Published: May 2021

Introduction: Uptake of evidence-based interventions for adolescents and young adults living with HIV (AYA-LWH) in sub-Saharan Africa (SSA) is complex, and cultural differences necessitate local adaptations to enhance effective implementation. Few models exist to guide intervention tailoring, yet operationalizing strategies is critical to inform science and implementation outcomes, namely acceptability, appropriateness, feasibility, fidelity, and sustainability. This paper describes operationalizing the ADAPT-ITT framework applied to a manualized trauma-informed cognitive behavioral therapy (TI-CBT) intervention addressing mental and sexual health for AYA-LWH in SSA in preparation for a randomized controlled trial (RCT).

Methods: Phase 1 of the RCT focused on operationalizing ADAPT-ITT steps 3–7 to tailor the intervention for use in eight sites across Botswana, Malawi, South Africa, and Zimbabwe. Well-defined processes were developed to supplement the general guidelines for each step to provide clear, consistent direction on how to prepare and conduct each step, including documenting, assessing, and determining adaptations, while maintaining intervention fidelity. The processes provided efficient standardized step-by-step progression designed for future replication. All sites participated in Phase 1 using the created tools and strategies to translate and present the TI-CBT to community stakeholders for feedback informing local adaptations.

Results: The research team developed and operationalized materials guiding adaptation. A translation review process verified local adaptability, maintained core concepts, and revealed differing interpretations of words, idioms, and culturally acceptable activities. Strategically designed tools comprised of feedback and translation verification forms resulted in meticulous management of adaptations. Robust collaborations between investigators, research managers, site personnel, and topical experts maximized multidisciplinary expertise, resulting in ~10–15 personnel per site facilitating, collecting, assessing, and integrating local feedback. Processes and tools operationalized in steps 3–7 effectively addressed implementation outcomes during community engagements (n = 108), focus groups (n = 5–8 AYA-LWH and caregivers per group), and strategic training of youth leaders.

Discussion: This paper offers a novel generalizable approach using well-defined processes to guide intervention adaptation building on the ADAPT-ITT framework. The processes strengthen the science of implementation and provide much-needed specificity in adaptation steps to optimize and sustain real-world impact and help researchers and community stakeholders maximize existing infrastructure, culture, and resources to inform implementation strategies.
Nationwide Subjective and Objective Assessments of Potential Talent Predictors in Elite Youth Soccer: An Investigation of Prognostic Validity in a Prospective Study
Authors: Höner Oliver , Murr Dennis , Larkin Paul , Schreiner Robert , Leyhr Daniel
Published: May 2021

Recent studies have provided empirical evidence on the prognostic relevance of objective performance diagnostics in the soccer talent identification and development process. However, little is known about the prognostic validity of coaches' subjective evaluations of performance. This study evaluated objective and subjective assessments within a nationwide talent development program and addressed motor, perceptual skill, and personality-related performance factors. Male players (N = 13,869; Mage = 12.59 ± 1.07 years) from the age groups U12 to U15 of the German soccer talent development program participated in this study. Participants completed an objective motor diagnostic (sprint, agility, dribbling, ball control, juggling) and were subjectively rated by their coaches (kicking skills, endurance, individual tactical skills, psychosocial skills). All nine predictors were assessed with sufficient psychometric properties (α ≥ 0.72; except dribbling and ball control: α ≥ 0.53). Players' success three seasons later was operationalized by achieving professional youth academy level or not (success rate, 9%). Independent-samples t-tests analyzed univariate mean group comparisons between future selected and non-selected players. Logistic regression models examined the multivariate prognostic validity of all assessments by predicting success with subjective (model 1), objective (model 2), and both groups of predictors (model 3). Confirming the univariate prognostic validity, future selected outperformed non-selected players regarding all predictors (each p < 0.001, except for agility in U15: p < 0.01). Tactical skills, kicking skills, and sprint were of highest predictive value (d ≥ 0.61 in each age group). Multivariate results provided empirical evidence for the subjective (7% ≤ Nagelkerke's R2 ≤ 11%; each p < 0.001) and objective (8% ≤ Nagelkerke's R2 ≤ 13%; each p < 0.001) assessments' prognostic validity. However, model 3 revealed the best statistical explanatory power in each age group (0.15 ≤ Nagelkerke's R2 ≤ 0.20; p < 0.001). In this combined assessment model, sprint, tactical skills, and dribbling were found to be the most predictive variables. In conclusion, this study reinforces the call for multidimensional diagnostics integrating objective and subjective assessments. Future research is needed to address the demands for longitudinal analyses of subjective ratings, the integration of biological maturation, and empirical evidence for female soccer.
Posterior Mediastinal Epithelioid Angiosarcoma Arising in Schwannoma: A Case Report and Review of the Literature
Authors: Xiang Yingming , Yan Liping , Lin Xia , Zhang Xiangyan , Zhang Fangbiao , Wu Zhijun
Published: May 2021

Epithelioid angiosarcoma arising in schwannoma is an extremely rare mesenchymal tumor that accounts for only 1 to 2% of all sarcomas. This type of tumor occurs in all parts of the body, most often in the skin and soft tissues and rarely in the mediastinum. The present study describes the case of an asymptomatic, 58-year-old male who presented with epithelioid angiosarcoma in the posterior mediastinum during a physical examination. Enhanced computed tomography of the chest revealed a 3.5 × 3.1-cm mass in the posterior mediastinum. Thoracoscopic mediastinal mass resection was performed under general anesthesia due to the possibility that the tumor was malignant. Pathological examination revealed the presence of angiosarcoma and schwannoma components. Immunohistochemical staining for cluster of differentiation (CD) 31, CD34, early growth response (EGR), vimentin, Sry-related HMG box (SOX)-10 and S-100 was strongly positive. The patient recovered and was discharged on postoperative day 5. Two months postsurgery, the patient returned for evaluation, and no evidence of tumor recurrence was observed.
Assessment of Volume Status and Fluid Responsiveness in Small Animals
Authors: Boysen Søren R. , Gommeren Kris
Published: May 2021

Intravenous fluids are an essential component of shock management in human and veterinary emergency and critical care to increase cardiac output and improve tissue perfusion. Unfortunately, there are very few evidence-based guidelines to help direct fluid therapy in the clinical setting. Giving insufficient fluids and/or administering fluids too slowly to hypotensive patients with hypovolemia can contribute to continued hypoperfusion and increased morbidity and mortality. Similarly, giving excessive fluids to a volume unresponsive patient can contribute to volume overload and can equally increase morbidity and mortality. Therefore, assessing a patient's volume status and fluid responsiveness, and monitoring patient's response to fluid administration is critical in maintaining the balance between meeting a patient's fluid needs vs. contributing to complications of volume overload. This article will focus on the physiology behind fluid responsiveness and the methodologies used to estimate volume status and fluid responsiveness in the clinical setting.
Impact of Fermented or Enzymatically Fermented Dried Olive Pomace on Growth, Expression of Digestive Enzyme and Glucose Transporter Genes, Oxidative Stability of Frozen Meat, and Economic Efficiency of Broiler Chickens
Authors: Ibrahim Doaa , Moustafa Amira , Shahin Sara E. , Sherief Wafaa R. I. A. , Abdallah Karima , Farag Mohamed F. M. , Nassan Mohamed A. , Ibrahim Seham M.
Published: May 2021

The use of dried olive pomace as complementary energy sources in poultry feed is still limited due to its low protein and high fiber contents. Bioconversion of olive pomace through solid-state fermentation with or without exogenous enzymes is considered as a trial for improving its nutritional value. This study aimed to evaluate the effects of fermented olive pomace with or without enzymatic treatment on the growth, modulations of genes encoding digestive enzymes and glucose transporters, meat oxidative stability, and economic efficiency of broiler chickens. A total of 1400 day-old broiler chicks (Ross 308) were randomly allocated to seven dietary treatments with 10 replicates of 20 birds/replicate. Treatments included control (basal corn–soybean diet) and other six treatments in which basal diet was replaced by three levels (7.5, 15, and 30%) of fermented olive pomace (FOPI) or enzymatically fermented olive pomace (FOPII) for 42 days. The highest body weight gain was observed in groups fed 7.5 and 15% FOPII (increased by 6.6 and 12.5%, respectively, when compared with the control group). Also, feeding on 7.5 and 15% FOPII yielded a better feed conversion ratio and improved the digestibility of crude protein, fat, and crude fiber. The expression of the SGLT-1 gene was upregulated in groups fed FOPI and FOPII when compared with the control group. Moreover, the expression of the GLUT2 gene was elevated in groups fed 7.5 and 15% FOPII. By increasing the levels of FOPI and FOPII in diets, the expression of genes encoding pancreatic AMY2A, PNLIP, and CCK was upregulated (p < 0.05) when compared with the control. Fat percentage and cholesterol content in breast meat were significantly reduced (p < 0.05) by nearly 13.7 and 16.7% in groups fed FOPI and FOPII at the levels of 15 and 30%. Total phenolic and flavonoid contents in breast meat were significantly increased in groups fed 15 and 30% FOPI and FOPII when compared with the control group and even after a long period of frozen storage. After 180 days of frozen storage, the inclusion of high levels of FOP significantly increased (p < 0.05) the levels of glutathione peroxide and total superoxide dismutase and meat ability to scavenge free radical 1,1-diphenyl-2-picrylhydrazyl. Furthermore, the highest net profit and profitability ratio and the lowest cost feed/kg body gain were achieved in groups fed 7.5 and 15% of FOPII, respectively. The results of this study indicated that dietary inclusion of 15% FOPII could enhance the growth performance and economic efficiency of broiler chickens. Moreover, a higher inclusion level of FOPI or FOPII could enhance the quality and increase the oxidative stability of frozen meat and extend the storage time.
Choice of Modern Food Distribution Channels and Its Welfare Effects: Empirical Evidence from Taiwan
Authors: Chang Yun-Cih , Wei Min-Fang , Luh Yir-Hueih
Published: May 2021

The determinants and/or economic effects of modern food distribution channels have attracted much attention in previous research. Studies on the welfare consequences of modern channel options, however, have been sparse. Based on a broader definition of modern food distribution channels including midstream processors and downstream retailers (supermarkets, hypermarkets, brand-named retailers), this study contributes to the existing body of knowledge by exploring the distributional implications of farm households’ choice of modern food distribution channels using a large and unique farm household dataset in Taiwan. Making use of the two-step control function approach, we identify the effect of modern food distribution options on farm households’ profitability. The results reveal selling farm produce to modern food distributors does not produce a positive differential compared to the traditional outlets. Another dimension of farm household welfare affected by the choice of modern food distribution channel is income inequality. We apply the Lerman and Yitzhaki decomposition approach to gain a better understanding of the effect of the marketing channel option on the overall distribution of farm household income. The Gini decomposition of different income sources indicates that the choice of modern food distribution channels results in an inequality-equalizing effect among the farm households in Taiwan, suggesting the inclusion of smallholder farmers in the modern food distribution channels improves the overall welfare of the rural society.
Cotton Emergence and Yield Response to Planter Depth and Downforce Settings in Different Soil Moisture Conditions
Authors: Virk Simerjeet , Porter Wesley , Snider John , Rains Glen , Li Changying , Liu Yangxuan
Published: May 2021

US cotton producers are motivated to optimize planter performance to ensure timely and uniform stand establishment early in the season, especially when planting in sub-optimal field conditions. Field studies were conducted in 2017, 2018 and 2019 to evaluate the effect of seeding depth and planter downforce on crop emergence and yield in cotton planted in different soil moisture conditions. Field conditions representative of dry, normal and wet soil moisture conditions were attained by applying 0, 1.27 and 2.54 cm of irrigation within the same field. Two cotton cultivars (representing a small-seeded and a large-seeded cultivar, 9259–10,582 and 11,244–14,330 seeds kg−1, respectively), were planted at seeding depths of 1.3, 2.5 and 3.8 cm with each seeding depth paired with three different planter downforces of 0, 445 and 890 N in each block. Cotton was planted in plots that measured 3.66 m (four-rows) wide by 10.67 m long. Results indicated that crop emergence was affected by the seeding depth across most field conditions and higher crop emergence was observed in the large-seeded cultivar at 1.3 and 3.8 cm seeding depths in dry and wet field conditions, respectively. Lint yield was also higher for the large-seeded cultivar at the 3.8 cm seeding depth across all field conditions in 2017, and in dry field conditions in 2018. Planter downforce effect on crop emergence varied among the cultivars where the large-seeded cultivar exhibited higher crop emergence than the small-seeded cultivar at 445 and 890 N downforce. Planter downforce of 445 N yielded greater than the 0 and 890 N treatment in dry field conditions in 2017. The study results suggest that matching planter depth and downforce settings for prevalent soil moisture conditions at planting along with appropriate cultivar selection can help in achieving optimal emergence and yield in cotton.
Changes in Microstructure, Germination, Sprout Growth, Phytochemical and Microbial Quality of Ultrasonication Treated Adzuki Bean Seeds
Authors: Chiu Kai-Ying
Published: May 2021

Sprout is a nutritious ready-to-eat vegetable. In this study, we examined the effects of ultrasonication treatments (treated with 28, 40 or 80 kHz frequency for 10 min at 25 °C) on the changes in microstructure, seed hydration and germination, sprout growth, sprout quality, and microbial load of two adzuki bean (Vigna angularis) varieties (Kaohsiung 8 and Kaohsiung 10). The results indicated that the ultrasonication at 40 kHz or 80 kHz improved seed hydration and enhanced germination; this is linked to the ultrasound-induced microstructure changes in the hilum and seed coat surface of treated seeds. The ultrasonication-increased sprout growth and yield were possibly attributable to the increased α-amylase activity during germination. Ultrasonication also improved total polyphenols, total flavonoids, and total saponins contents and further enhanced the anti-oxidative activities (FRAP and DPPH) of produce sprouts. The results further indicated that the 40 kHz or 80 kHz treatment decreased microbial loads of treated sprouts to an acceptable level; therefore, these two treatments can be used for germination improvement and an effective microbial control treatment for adzuki bean sprout production.
Mare’s Milk from a Small Polish Specialized Farm—Basic Chemical Composition, Fatty Acid Profile, and Healthy Lipid Indices
Authors: Czyżak-Runowska Grażyna , Wójtowski Jacek Antoni , Danków Romualda , Stanisławski Daniel
Published: May 2021

The objective of this study was to determine the chemical composition, fatty acid profile, and values of healthy indices of milk from a specialized farm of Polish Coldblood mares of different ages, birth orders, and lactation stages. Milk samples (n = 48) were collected for analysis in weeks 10, 15, and 25 of lactation from mares aged between five and 14 years. The study showed that the stage of lactation has a significant effect on the fatty acid (FA) profile of the milk produced on the farm. The highest concentration of monounsaturated and polyunsaturated FAs was found in milk produced from the 15th week of lactation. The milk was also characterized by low values of atherogenic and thrombogenic indices, which indicate the health benefits of milk with respect to the content of fatty acids and their potential to prevent or cause atherosclerosis and thrombosis. The study also found a significant correlation between the number of foalings (birth order), the fatty acid profile, and atherogenic index of milk produced on the farm. The findings from the study indicate that it is possible to modify the fatty acid profile of bulk tank milk through appropriate management of the age structure of the herd of mares. To confirm this dependence, the study will be continued on a larger group of mares.
In Vitro Neutral Detergent Cellulase Method and Chemical Composition to Predict In Vivo Fermentable Organic Matter of Roughages
Authors: Liu Yue , Li Rui , Wu Hao , Meng Qingxiang , Khan Muhammad Zahoor , Zhou Zhenming
Published: May 2021

In Vivo fermentable organic matter (FOM) reflects the energy production and the potential of rumen’s microbial protein synthesis. However, the in vivo method with fistulated animals for FOM measurement compromises animal welfare and is laborious as well as expensive. Although the alternative in situ nylon bag technique has been widely used, it is also costly and requires rumen liquor. Therefore, the present study was performed to compare the in situ nylon bag technique with the in vitro neutral detergent cellulase (NDC) method or chemical composition to estimate in vivo FOM of roughages. For this purpose, we selected 12 roughages, including six each from forages and crop residues. Our results have shown the strong correlation equations between FOMin situ and FOMNDC of forages (n = 6; R2 = 0.79), crop residues (n = 6; R2 = 0.80), and roughages (n = 12; R2 = 0.84), respectively. Moreover, there were also strong correlations between the chemical composition of roughages and FOMin situ (n = 12; R2 = 0.84–0.93) or FOMNDC (n = 12; R2 = 0.79–0.89). In conclusion, the in vitro NDC method and chemical composition were alternatives to in situ nylon bag technique for predicting in vivo FOM of roughages in the current experiment.
Determinants of Bird Species Literacy—Activity/Interest and Specialization Are More Important Than Socio-Demographic Variables
Authors: Randler Christoph , Heil Felicitas
Published: May 2021

Biodiversity is declining, and knowledge about biodiversity declines in a similar way. Previous studies have already addressed predictors of species knowledge. Here, we studied bird species knowledge related to demographics, but also to individual differences in affinity to nature, by including (i) birding specialization and (ii) bird-related activities/interest. Data were collected from July to October 2020 via an online questionnaire, containing demographic data, birding specialization, interest/activity, and images of 28 bird species native to Germany. Participants were adult students, lecturers and administrative staff of the Eberhard Karls University Tübingen. A total of 1967 questionnaires were returned in this study (35.3% male, 53.8% students, 69% had access to a garden). Mean identification score was 16.31 ± 6.38. Thus, participants were able to identify more than half of the species (total species n = 28). Men identified more species than women, garden owners had higher identification scores than non-owners, while hometown size was not significant. A distance to the next forest patch >10 km was related to lower identification scores. Employees scored higher than students. Correlation between species knowledge and birding specialization was high, as was the correlation with bird interest/activity. Higher scores were found in older people. In the linear univariate model, birding specialization and bird interest were the most influential predictors of species knowledge, followed by distance to next forest patch and occupation (student vs employees). Other variables were not significant. We suggest including such measures (interest, attitude, etc.) into further studies and move forward from the urban–rural narrative to more complex analyses of living circumstances.
Compared with Cotrimoxazole Nitroxoline Seems to Be a Better Option for the Treatment and Prophylaxis of Urinary Tract Infections Caused by Multidrug-Resistant Uropathogens: An In Vitro Study
Authors: Dobrindt Ulrich , Wami Haleluya T. , Schmidt-Wieland Torsten , Bertsch Daniela , Oberdorfer Klaus , Hof Herbert
Published: May 2021

The resistance of uropathogens to various antibiotics is increasing, but nitroxoline remains active in vitro against some relevant multidrug resistant uropathogenic bacteria. E. coli strains, which are among the most common uropathogens, are unanimously susceptible. Thus, nitroxoline is an option for the therapy of urinary tract infections caused by multiresistant bacteria. Since nitroxoline is active against bacteria in biofilms, it will also be effective in patients with indwelling catheters or foreign bodies in the urinary tract. Cotrimoxazole, on the other hand, which, in principle, can also act on bacteria in biofilms, is frequently inactive against multiresistant uropathogens. Based on phenotypic resistance data from a large number of urine isolates, structural characterisation of an MDR plasmid of a recent ST131 uropathogenic E. coli isolate, and publicly available genomic data of resistant enterobacteria, we show that nitroxoline could be used instead of cotrimoxazole for intervention against MDR uropathogens. Particularly in uropathogenic E. coli, but also in other enterobacterial uropathogens, the frequent parallel resistance to different antibiotics due to the accumulation of multiple antibiotic resistance determinants on mobile genetic elements argues for greater consideration of nitroxoline in the treatment of uncomplicated urinary tract infections.