bluuebunny/crossref_metadata_2025 huggingface dataset:
DYNAMICS OF CHANGES IN THE SERUM MINERAL METABOLISM OF YOUNG PEOPLE WITH GENERALIZED PERIODONTITIS ON THE BACKGROUND OF PRIMARY HYPOTHYROIDISM
Authors: Repetska O.M. , Rozhko M.M. , Dmytryshyn T.M. , Kostyshyn A.B.
Published: April 2021

At present, there is no definitive opinion on the effect of thyroid hormones on bone metabolism, as the dualism of their effects has been proven. Various studies show mixed data on metabolic changes in periodontal tissues on the background of thyroid dysfunction. Bone tissue plays a key role in the complex system of mechanisms of regulation of calcium and phosphorus homeostasis in the body. The processes of modeling and remodeling of bone and its mineralization are closely related to calcium metabolism. The biochemical manifestation of osteoporotic processes in the cell bone in generalized periodontitis is a violation of calcium-phosphorus homeostasis on the background of altered markers of bone metabolism. According to the literature, it is known that the main indicator of calcium-phosphorus metabolism is the content of calcium in the serum. However, for the metabolic characteristics of the inflammatory-dystrophic process in the cell bone, it is necessary to study the level of inorganic phosphorus and calculate the molar ratio of calcium / phosphorus. The calcium / phosphorus ratio in the blood is important for the study of calcium deposits in bone tissue. Maintenance of normal bone structure depends on the exchange of phosphates between blood and bone tissue. Magnesium along with calcium is needed to achieve optimal bone mineral density. Magnesium helps maintain normal levels of calcium in bone tissue, its constant renewal in bone, prevents calcium loss. With limited intake of magnesium, the formation of calcium phosphate is inhibited. In order to establish indicators that would reflect the peculiarities of metabolic disorders in the organic matrix of the cell process, which is the main component of the periodontium, we conducted biochemical studies, which included the study of calcium-phosphorus metabolism and serum magnesium in patients with primary hypothyroidism and persons without endocrine pathology. According to the results of studies, in young people with generalized periodontitis on the background of reduced thyroid function, there were violations of calcium-phosphorus metabolism in the serum, which consisted of hypocalcemia and decreased calcium-phosphorus ratio. This may indicate abnormalities in calcium intake and absorption in patients with hypothyroidism. We attribute this fact to the fact that for the normal absorption and metabolism of calcium, thyroid hormones are needed, the production of which is reduced in this endocrine pathology. Data on the negative changes of calcium-phosphorus homeostasis, and especially the violation of calcium absorption by patients with generalized periodontitis in young people with primary hypothyroidism, should be considered when developing schemes for the treatment and prevention of periodontal disease in this category of patients.
ANTIMICROBIAL EFFECT OF IODOFORM AND CHLORHEXIDINE ON MUSEUM STRAINS OF MICROORGANISMS
Authors: Chumak Yu. V. , Ananieva M. M. , Faustova M. O. , Loban G. A. , Havryliev V. M.
Published: April 2021

Surgical tooth extraction can result in a number of complications. Alveolitis is an infectious and inflammatory process in the walls of a tooth socket that may occur after tooth extraction during at the oral surgery outpatient appointment. This condition is characterized by a partial or complete absence of a blood clot, called as "dry socket", and pain syndrome. There are various factors, which can contribute to the development of this process, but the most common are traumatic and infectious ones. For the local treatment of alveolitis, a number of drugs are used to eliminate inflammatory manifestations and pain syndrome. During an outpatient appointment for the treatment of alveolitis, antiseptic drugs as iodoform and chlorhexidine are most often used. Iodoform is an antiseptic widely used locally in oral surgery and in endodontics. Chlorhexidine is also widely used in dentistry as an antiseptic. The aim of this in vitro study is to investigate the antimicrobial properties of iodoform and chlorhexidine using museum strains of microorganisms. Materials and methods. Museum strains of Staphylococcus aureus ATCC 25923, Staphylococcus epidermidis ATCC 14990, Enterococcus faecalis ATCC 29212, Esherichia coli ATCC 25922, Candida albicans ATCC 10231 were used the studied cultures of microorganisms. The antimicrobial effect of iodoform and chlorhexidine was determined by a quantitative method of serial dilutions in broth and agar. For this purpose, we used iodoform suspension, which corresponded to 200.0 mg / ml of the working concentration of the agent. A 0.05% solution of chlorhexidine bigluconate was used that corresponded to 500 μg / ml of the working concentration of the agent. Results and discussion. Iodoform as powder in the studied concentrations caused an insignificant static effect on museum strains of E. faecalis, E. coli, but did not exhibit a bactericidal effect against them. In relation to the C. albicans strain, iodoform demonstrated fungiostatic properties. The S. epidermidis and S. aureus strains were resistant to iodoform. Chlorhexidine caused both inhibitory and microbicidal action on all studied strains of microorganisms.
Heterotopia as an Environmental and Political Concept: The Case of Hannah Arendt's Philosophy
Authors: Lisowska Urszula
Published: April 2021

The paper offers a new model of politics adequate for the Anthropocene epoch. It uses the concept of ‘heterotopia’ to argue for the environmental potential of Arendtian political philosophy. The adopted meaning of heterotopia combines its Foucauldian (as interpreted by L. De Cauter and M. Dehaene) and medical sources. It is argued that, thus understood, the concept can be applied to the Arendtian idea of judgment. In this capacity, the concept of heterotopia is both politically foundational and environmentally relevant. It helps us maintain the idea of politics as humanely construed activity, while recognising that political actors are also natural beings, whose actions draw on and affect the non-human world.
The Acoustic Effect of Urdu Phonological Rules on English Speech
Authors: Farooq Mahwish , Mahmood Asim
Published: April 2021

The paper is about the acoustic effect of Urdu phonological rules on Pakistani Urdu speakers' English speech. The objective of the study is to discuss the phenomenon of multiple pronunciations of an English word that has the same spellings, meaning, and part of speech but different pronunciations in the English speech of Urdu speakers. Sometimes these alternative pronunciations are considered mispronunciation rather than multiple pronunciations. The primary purpose of this study is to make a boundary-line between mispronunciations and multiple pronunciations of English vocabulary. Thus, an acoustic analysis of Urdu speakers' English speech has been done by collecting speech data of 30 Urdu speakers from the Public sector universities of Pakistan. Consequently, this paper caters to language-dependent variations of Urdu. This paper only deals with three phonological rules, i.e., segment alternation, ellipsis, epenthesis, which become the cause for re-syllabification of English words. These three foci of research have been selected because the data analysis has confirmed that the 'multiple pronunciation' is mainly occurred due to these three elements. These three categories cover several sub-categories that cover many instances in the data analysis. The data also confirms that phonological variations occur due to stress shifting in Urdu speakers' English speech in Pakistan.
Visión de túnel y persecución penal
Authors: Beltrán Román Víctor
Published: April 2021

El presente comentario analiza una sentencia absolutoria del Tribunal de Juicio Oral en lo Penal de Colina que tuvo como principal fundamento la vulneración al debido proceso, como consecuencia de la visión de túnel que afectó a los funcionarios policiales durante la etapa de investigación. El objetivo del presente comentario es entregar una breve noción general del concepto visión de túnel, para luego comentar la decisión absolutoria, sistematizando el razonamiento del tribunal.
Design of a dynamic positioning for unmanned surface vehicles using GPS/INS (VIAM-NAVI-M)
Authors: TRAN HUY NGOC , Cuong Nguyen Tu
Published: April 2021

Today, Unmanned Surface Vehicles (USV) maintain the direction and fixed position necessary for many different applications such as security patrol, transmit information, water sampling, environmental monitoring... With USV model with two hull, control and propulsion systems, both of which are specifically designed to allow the vehicel to perform this task flexibly, omnidirectional and maneuverable. With environmental effects, such as wind, waves and currents ..., it has a large impact on ships, leading to large errors or fluctuations. Therefore, a controller designed to produce better performance for USV under changing noise conditions is essential. To improve the ability of navigation for vehicles, Viam-Navi-M GPS/INS Module: integration of Inertial Navigation System (INS) and Global Positioning System (GPS) is developed with low-cost, highly accurate and stable navigation system. At the same time, the article will present the process of system development and software architecture design. Finally, with the four engine and controller propulsion system built and tested, it shows that the boat is well controlled, its ability to maintain specific direction and position for long periods of time. The postion error is maintained less than 1 meter most of the experimental time and the heading error is between -5 and +5 degrees.
Fabrication technology for aluminium-alloy tanks carrying petroleum and chemical substances in Viet Nam
Authors: Hung Dao Quoc , Trần Thanh Dũng , Đinh Văn Thắng , Huỳnh Nhật Duy , Thượng Công Lập
Published: April 2021

Compared to steels, aluminium-alloys are comparably strong but 3 times lighter, inoxidable and unfavorable to producing mechanical sparks. Aluminium alloys are therefore attractive materials and have been widely applied to transportation industry in developed countries since 1950s. An alunimium-alloy tank has upto 20% more useful volume than a steel tank for the same total weight. Interior and exterior protective coatings are unnecessary, significantly saving annual maintenance costs and preventing any contamination from abrasion of interior protective coatings. In additional, an aluminim-alloy tank does not ignite a fire in traffic accident. In G7 regions as well as many developed countries in Europe and Asia, only tanks made from aluminim alloys are approved for carrying danger liquids such as petroleum and chemical substances. In Vietnam, International Machine And Equipment (IMAE) Company is considered as a pioneer in designing and manufacturing aluminium alloy-tanks satisfying American DOT 406 Standard for tank trucks and semi-trailers. With optimized designing and manufacturing processes in conjunction with quality control system and continuous improvement, product quality is strictly maintained, quickly providing benefits to customers. Using an aluminium-alloy tank for carrying petroleum for 25 years, a complete payback can be achieved after only 7 months although initial investment is considerablely high.
Vibration Analysis of a Bus’s Air Spring Suspension Subjected to Random Road Profile
Authors: Nhan TRAN Huu
Published: April 2021

Vehicle dynamics model in type of 1/4 is used for vibration analysis under the effect of random road profile with different grades. The mathematical model to describe the used random road profile is able to change the type of investigated road grades by selecting the corresponding power spectral density parameter of the road grade according to the ISO 8608 standard. Random road profile is ivestigated in the range of frequency domain from 0 to 50 (Hz). The air spring stiffness and the damping coefficience are determined on the basis of reference to the practical vehicle. The variation of relative displacement amplitude of the suspension in the range of investigation domain is small, the air spring stiffness used in the calculation is constant. The obtained results corresponding to different grades of road surface roughness including displacement and acceleration parameters. Relative displacement is a parameter that aims to verify the ability to ensure safe working of the suspension, namely rattle spacing. Acceleration is used to evaluate the vehicle's comfort. Calculation results are analyzed as the basis for evaluating the influence of the air spring stiffness and road surface conditions on the comfort of the vehicle, as the basis for changing the air spring stiffness in accordance with adjusting the pressure of it according to the type of road profile quality.
COMPARISON BETWEEN SERUM CREATININE AND SERUM CYSTATIN C LEVEL IN DIAGNOSING EARLY DIABETIC NEPHROPATHY IN NEWLY DIAGNOSED TYPE 2 DIABETES MELLITUS
Authors: Prasad Janmeshwar , Singh Manish Kumar , Anwer Md. Rashid , . Shyama
Published: April 2021

Background: This study was done to evaluate clinical usefulness of cystatin C levels of serum and urine in predicting renal impairment in normoalbuminuric patients with type 2 diabetes and to evaluate the association between albuminuria and serum/urine cystatin C. Cockroft-Gault equation was previously used for GFR calculation. The most recently advocated formula for calculating the GFR are The modification of diet in renal disease study group ,CKD-EPI equation(2009),CKD-EPI cystatin C(2012), CKD-EPI creatinine –cystatin C(2012). The cystatin C levels of serum and urine could be useful markers for renal dysfunction in type 2 diabetic patients with normoalbuminuria.

Conclusion; This finding has major implications for clinical research and early intervention to prevent development of chronic kidney disease in patients with type 2 Diabetes mellitus.

Keywords: Cystatin C, Diabetic Nephropathies, Albuminuria
PHYTOCHEMICAL SCREENING AND ANTIACNE ACTIVITY OF LEAVES EXTRACT OF LAGERSTROEMIA INDICA
Authors: Vishwakarma Vandana , Patel Narendra , Budholiya Prabhakar
Published: April 2021

Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Secondary constituents contain alkaloids, flavonoids, phenol, sapon in, steroids and tannins. Medicinal plants have anticancer, antimicrobial, antidiabetic, antidiuretic and anti-inflammation activities. The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. In Indian Ayurvedic system, Lagerstroemia Indica (Lythraceae) are well-known plants used for major and minor ailments. The aim of the present study is to examine leaf of Lagerstroemia Indica for phytochemical profile, antioxidant potential, antimicrobial including anti acne activity. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by FolinsCiocalteau reagent method and aluminium chloride method respectively. Phytochemical analysis revealed the presence of phenols, flavonoids, tannins, saponins, alkaloids, fixed oil and fats. The present study concluded that the crude extract of Lagerstroemia Indica is a rich source of secondary phytoconstituents which impart significant antioxidant potential.  The extract of Lagerstroemia Indica possess antimicrobial effectiveness againt P. acne and other microbes, In Vitro anti acne activity. The findings of the present study will be helpful to phytochemists, pharmacologists and pharmaceutical industries.

Keywords: Lagerstroemia Indica, Phytochemical, Antioxidant, Antiacne.
Another approach on elaborating frequency tables using GAUSS´s normal distribution theory
Authors: Victorino Samuel Carlos
Published: April 2021

The correct organization of data is of extreme importance for the analysis in the process of statistical inference, aiming at the elaboration of valid conclusions and generic recommendations on a certain subject under study. The specialized scientific literature describes several procedures for the organization of data in frequency distribution tables. However, it is not often that inaccuracies are made in the use of data organization tools. These inaccuracies have resulted in distorted analyzes and incongruous conclusions. This paper presents a critical analysis of the methods and procedures of data organization described in the literature, specifically the distribution of data in frequency distribution tables and proposes a different approach in the elaboration of class frequency distribution tables. For all variables with predefined categories, these and their respective reference values serve as the body of the table. For the variables that do not have pre-defined categories, the use of Gauss’s normal distribution theory as a criterion for categorization is proposed and justified. The categories generated serve as a table body. It is concluded that the frequency distribution tables can be distinguished into two types, that is, frequency distribution tables of predefined classes or categories and tables of frequency distribution of classes or categories to be defined, thus suggesting their adoption as concept.
Desenvolvimento de Uma Aplicação de Gerenciamento de Projetos Arquitetônicos Baseada no Toolkit HCD
Authors: Francisco Alesson Delmiro , Andrade Danyllo Gomes Figueredo de , Gouveia Roberta Macêdo Marques
Published: April 2021

Este artigo apresenta o desenvolvimento de uma aplicação computacional de gerenciamento de projetos arquitetônicos, com base no Toolkit HCD (Human Centered Design), com vistas a auxiliar o gerenciamento de projetos de arquitetura. Dentre os objetivos do trabalho, tem-se o desenvolvimento de um protótipo, utilizando a plataforma proto.io, visando prover um meio de comunicação eficiente e confiável para arquitetos e clientes. A ferramenta de gerenciamento de projetos de arquitetura proposta neste trabalho dispõe de uma boa interface humano-computador, por meio dos critérios de usabilidade de Jakob Nielsen. Em relação à metodologia do trabalho, são contempladas as duas primeiras fases do Toolkit HCD, a fase “ouvir” e a fase “criar”, que são fundamentais para que se alcance um bom resultado na criação de produtos inovadores.
Exemption des appels d’offres dans les achats publics de l’État du Pará
Authors: Marzzoni David Nogueira Silva , Oliveira Mario Cesar Sousa de , Barcelos Tiago Soares
Published: April 2021

Cet article présente une analyse des contrats directs prévus par la loi n° 8 666/1993 et la loi n° 13 979/2020, pendant la pandémie de Covid-19. Cela dit, il vise à déterminer combien ont été les dépenses engagées par l’État de Pará au cours des 10 dernières années pour des contrats directs exécutés, en particulier par le biais de l’exemption des appels d’offres. Il s’agit d’une recherche bibliographique sur le sujet, qui visait à contribuer et à mettre en évidence la compréhension des aspects qui couvrent les marchés publics. Dans l’intervalle, il est encore caractérisé comme une étude de cas qui visait à identifier les montants dépensés par le gouvernement sur les achats, effectués uniquement par l’État du Pará. Pour mener à bien la recherche, les données recueillies ont été obtenues au moyen des portails de transparence des achats « compraspara.pa.gov.br » qui ont fait en sorte que les processus de passation des marchés publics soient effectués par les organismes et les « transparenciacovid19.pa.gov.br » associés aux achats d’urgence et aux contrats liés à Covid-19, et plus tard, une analyse du contenu du thème proposé a été effectuée. En bref, selon les résultats, il a été possible de vérifier qu’il y avait une anticipation de l’État du Pará à dépenser 202 millions en achats au début de la pandémie alors qu’il y avait peu de données scientifiques à l’appui des décisions politiques, qui à la fin du premier semestre de 2020 avaient déjà atteint 419 millions. Ces dépenses n’ont pas empêché l’État du Pará de présenter le taux le plus élevé de cas signalés et de décès confirmés parmi les unités fédératives, dépassant même l’État du Minas Gerais, qui, s’il est comparé, compte deux fois plus d’habitants.
A inserção das novas tecnologias digitais na educação em tempos de pandemia
Authors: Lima José Maria Maciel
Published: April 2021

O presente estudo se caracteriza como uma pesquisa bibliográfica, com uma abordagem de cunho qualitativa, com dados e informações colhidas em websites, blogs, artigos científicos e livros. Tem como principal objetivo discutir a inserção das novas tecnologias da informação e comunicação, nas práticas pedagógicas remotas, em tempos de Pandemia. Inicialmente, aborda-se o contexto educacional no momento pandêmico, enfatizando o fechamento das escolas, o distanciamento social e a difícil realidade dos professores em ter que se habituar ao “novo normal” das aulas remotas. Em seguida, aborda-se a inserção das novas tecnologias digitais na educação e suas contribuições para o ensino remoto, salientando o papel do professor como um agente fundamental para dar continuidade as atividades pedagógicas fora do ambiente tradicional de sala de aula. Endossando esta seção, no próximo tópico, segure-se algumas ferramentas do Google que podem ser bastante úteis, se o professor souber aproveitá-las, tanto em momento pandêmico, quanto em outras situações. E para finalizar, apresenta-se um relato de experiência de uma professora da rede municipal de ensino, do município de Carnaíba (PE). Em linhas gerais, os estudos nos revelaram que as tecnologias da informação e comunicação devem ser integradas a educação, não somente por causa da pandemia, mas por fazerem parte da vida da maioria dos alunos, e serem ferramentas e recursos que podem contribuir com a formação plena dos discentes, protagonizando os seus projetos de vida e prepará-los para viverem na sociedade do século XXI.
O ensino de língua inglesa com ênfase nas habilidades comunicativas: Ler, escrever, falar e ouvir
Authors: Lima José Maria Maciel
Published: April 2021

O presente trabalho tem como objetivo discutir e propor estratégias de ensino que contemplem as quatro habilidades linguísticas para o ensino de Língua Inglesa, que podem ser úteis para desenvolver a competência comunicativa no educando e contribuir com a formação integral do aluno, como prevê os PCNs de LEM, a LDB 9394/96 e outras diretrizes curriculares. Para isso, parte-se de uma investigação bibliográfica de cunho qualitativo, para fazer uma breve abordagem sincrônica e diacrônica do ensino de Língua Inglesa, nas Escolas Públicas brasileira, procurando verificar como era no passado e como está na atualidade a situação e a oferta do Inglês, como disciplina obrigatória que compõe o currículo nacional. Além disso, faz-se uma breve discussão sobre as dificuldades de se trabalhar com as quatro habilidades, nas escolas públicas brasileiras, considerando a carência de material didático e as condições física-estruturais dos estabelecimentos de ensino, defendendo que essas dificuldades podem ser substituídas pela criatividade do professor. Para isso, utilizou-se como principal fonte bibliográfica os PCNs de LEM (1998) e diversos estudiosos que discutem o assunto. Em seguida, é feito uma abordagem teórica sobre a importância das quatro habilidades para desenvolver a competência comunicativa no aluno. E por fim, sugerem-se algumas estratégias de ensino que podem ser úteis para o ensino de língua inglesa, contemplando todas as habilidades comunicativas. Após essas considerações e análises, conclui-se que é possível aprender inglês nas escolas pública brasileiras, sendo necessário para isso, esforço, criatividade, formação continuada, motivação, investimento do governo em recursos tecnológicos e dedicação do professor.
ОЦІНКА ФІНАНСОВОЇ СТІЙКОСТІ БАНКІВСЬКОЇ СИСТЕМИ НА ОСНОВІ ІНДИКАТОРІВ ТА ЕКОНОМІЧНИХ НОРМАТИВІВ НБУ ЯК ІНСТУМЕНТІВ МОНЕТАРНОГО РЕГУЛЮВАННЯ
Authors: Лінтур Інна , Демчик Світлана
Published: April 2021

Стаття присвячена аналізу основних індикативних показників діяльності банківської системи України з ціллю оцінки її фінансової стійкості з метою монетарного регулювання. Охарактеризовано інструментарій регулювання банківської діяльності через фінансів індикатори економіці нормативи Національного банку України. Проаналізовано моніторинг та аналіз фінансів індикаторів фінансової стійкості банків, що дозволило сформувати висновки про існуючі показники та ймовірність виникнення відхилень розвитку банківської системи, розробити пропозиції щодо застосування інструментів управління банківським сектором. Сформовано висновки про неефективну діяльність комерційних банків, внаслідок якої банки зазнають збитків та відбувається скорочення капіталу банків і триває тенденція до погіршення їх фінансової стійкості та ефективності діяльності.
СУЧАСНИЙ СТАН СИСТЕМИ УПРАВЛІННЯ ДЕРЖАВНИМИ ЛІСОГОСПОДАРСЬКИМИ ПІДПРИЄМСТВАМИ ТА ШЛЯХИ ЇЇ УДОСКОНАЛЕННЯ
Authors: Хорошко Олег
Published: April 2021

Проаналізовано існуюче законодавче регулювання системи управління лісовою галуззю в світовій практиці та окремо описано його стан в Україні. Проаналізовано погляди науковців на зміст головних понять та наведено найкращі підходи до їх трактування. Оцінено економічний стан лісової галузі в системі економіки України та розглянуті шляхи удосконалення системи управління державними лісогосподарськими підприємствами. Наголошено, що пріоритетними напрямами удосконалення системи управління державними лісогосподарськими підприємствами України є: інституційні зміни – вибір організаційної моделі управління та встановлення розподілу численних функцій; удосконалення фінансово-економічного механізму функціонування лісового господарства; формування у державних структур управління лісовим господарством належного мотиваційного механізму; створення умов для організації об’єктивного контролю дотримання нормативно-правових актів щодо використання та відтворення лісів.
СУЧАСНІ НАПРЯМКИ РОЗВИТКУ КУРОРТНОГО ГОТЕЛЮ
Authors: Кирпіченкова Оксана , Ущаповський Артем , Боброва Ярослава
Published: April 2021

В даній статті пропонуються сучасні рішення для курортного готелю в місті Приморськ Запорізької області, які пов’язані з морськими екскурсіями та інноваційним підходом до кейтерингу. Вітчизняні готелі залучають нових гостей нестандартними послугами, зручностями, доброзичливою атмосферою, відпочинком, обстановкою, романтикою, емоціями, адреналіном. Запропоновано ряд морських екскурсій різної тривалості, що будуть супроводжуватися кейтерингом. Кейтеринг нині є одним із найбільш динамічних секторів ресторанного бізнесу в Україні. Крім того, важливе значення має не лише постачання їжі, а й організація відповідних масових заходів. Окрім прослуховування екскурсій на суднах, гостей також залучатимуть в процес створення страв – найбільш затребуваний сьогодні прийом.
Медико-психологический подход в лечении пациентов с полной адентией съемными конструкциями зубных протезов с опорой на дентальные имплантаты, установленные с применением хирургических шаблонов
Authors: Рубникович С.П. , Грищенков А.С.
Published: April 2021

Лечение пациентов с полной адентией съемными конструкциями зубных протезов, с опорой на дентальные имплантаты, установленные по индивидуальным хирургическим шаблонам, обеспечивает восстановление функции и эстетики, а также формирует правильное отношение к процессу реабилитации. Цифровые технологии в рамках медико-психологического подхода способствуют не только должному планированию хирургического и ортопедического этапов, но и коррекции патологических эмоциональных и поведенческих особенностей личности.
Цель исследования. Выявить особенности медико-психологического подхода при лечении стоматологических пациентов с полной адентией съемными конструкциями зубных протезов с опорой на дентальные имплантаты, установленные по индивидуальным хирургическим шаблонам.
Объекты и методы исследования. В основу клинической части работы положены результаты обследования и лечения 20 пациентов в возрасте 45–65-ти лет с полной адентией верхней и нижней челюстей. Комплексная реабилитация, включающая изготовление съемных ортопедических конструкций, с опорой на дентальные имплантаты, в том числе с использованием индивидуальных хирургических шаблонов.
Результаты исследования и их обсуждение. Данные, полученные при обследовании пациентов первой и второй групп, указывают на высокую эффективность терапевтического ресурса. Детальное планирование и визуализация для пациента будущего процесса лечения, интеграция его в этот процесс, установка дентальных имплантатов с использованием хирургических шаблонов определяет успех будущей терапии.
Заключение. Использование систем дентальных имплантатов в совокупности с цифровыми методами планирования позволяет добиться высокой эффективности в реабилитации пациентов с полной адентией.
A unidade didática e dialética do trabalho de campo com a sala de aula
Authors: Ferreira Vinicius Cavalcanti
Published: April 2021

Fundamentada na psicologia do desenvolvimento, na pedagogia crítica, ativa e intuitiva, e no materialismo dialético, a presente exposição faz cuidadosa reflexão sobre: o método de ensino, o trabalho de campo, a didática e a prática de ensino da geografia. Disserta-se aqui à construção de um método consistente, estruturado na integração do trabalho de campo com a sala de aula. Destarte, encontram-se neste artigo os argumentos de validação desta integração metodológica, seus fundamentos teóricos, suas possibilidades, tais quais: seu potencial à multidisciplinaridade, à atividade e à criatividade na construção do conhecimento escolar, de maneira a unir teoria e prática, concreto e abstrato, numa unidade didática e dialética.
Estado neoliberal e políticas educacionais: discutindo sobre a formação de professores de geografia no Brasil
Authors: Araujo Junior Aloysio Marthins de
Published: April 2021

No Brasil, no início dos anos 1990, ao menos duas importantes medidas de caráter econômico foram impostas: diminuir a influência do Estado sobre as atividades produtivas e aumentar a produtividade por trabalhador. A escola e a educação de modo geral, deveriam também ser reorganizadas, sendo avaliados por sua qualidade e eficiência, com o objetivo de a educação básica formar estudantes capacitados para o mercado de trabalho. Intensificadas desde 2016, estão em andamento algumas ações sobre a educação básica e o ensino superior. Outro dado, é o incremento dos cursos à distância, muitos deles, voltados à formação inicial de professores (tais como a Geografia e a Pedagogia). Isto significa uma maior massificação do ensino superior, mas distante de uma formação integral. Tais reformulações objetivam retirar as responsabilidades do Estado e transferir à iniciativa privada tais encargos. O objetivo deste artigo é discutir a as políticas neoliberais sobre o sistema educacional e a formação de professores de geografia, especificamente. A metodologia desta pesquisa se caracteriza por uma abordagem qualitativa (conceituação, descrição e caracterização) e exploratória, cujos procedimentos indicam-se como bibliográficos, utilizando-se a análise dos resultados de maneira interpretativa (significantes, relações, causas e consequências). Conclui-se, mesmo que ainda parcialmente, que as reformas do Estado brasileiro sobre o ensino, visam criar uma educação utilitarista, menosprezando a formação integral do jovem e do futuro professor; se busca aumentar a participação do setor privado na educação em todos os níveis e, ainda, os professores têm que buscar melhor qualificação individualmente (e não como um projeto coletivo).
Resenha do filme Gabriel e a Montanha
Authors: Scheuenstuhl Bruno
Published: April 2021

O filme perfaz a última etapa da viagem do brasileiro Gabriel Buchmann à África em 2009 antes de morrer no Monte Mulanje, no sul do Malaui.
Educação ao ar livre e Geografia: caminhos possíveis no currículo brasileiro
Authors: Pereira Paola Gomes , Castrogiovanni Antonio Carlos
Published: April 2021

Nesse trabalho abordamos novas metodologias de ensino e aprendizagem e refletimos sobre resultados possíveis que possam emergir através dessas práticas. A Educação ao Ar Livre (Outdoor Education) é uma área de ensino bastante presente em países europeus, em especial, países de origem anglo-saxônica e germânica. No Brasil, a educação ao ar livre em alguns momentos é incorporada por institutos e organizações não governamentais, mas ainda é pouco explorada no ensino escolar. Pensamos sobre os caminhos possíveis que possam ser construídos através do diálogo com essa área no Brasil. Uma das nossas dúvidas é: o que diferencia a Educação ao Ar Livre de uma prática pedagógica realizada fora da sala de aula? Essa é uma das perguntas que orientará nossas reflexões nesse trabalho. Buscamos nessa pesquisa pensar a Educação ao Ar Livre voltada para o lugar, na qual o descobrimento da comunidade local e do espaço vivido está presente nas práticas de ensino e aprendizagem que buscam o exercício da cidadania. Dessa forma, uma educação que instigue o envolvimento com a comunidade local, a compreensão das características naturais do lugar e uma sensação de corresponsabilidade pelo espaço, pode contribuir para a formação cidadã e o cuidado com o espaço vivido. A pesquisa ainda se encontra em suas etapas iniciais e a metodologia desenvolvida até então foi constituída da construção de referencial teórico que permita refletir sobre os conceitos relacionados a temas como a Complexidade, a Educação ao Ar Livre, o ensino de Geografia, a Paisagem e o Lugar. Realizamos uma análise da Base Nacional Comum Curricular do Brasil, considerando os anos finais do Ensino Fundamental, na área das Ciências Humanas no componente curricular de Geografia, para a partir das competências pensadas para o componente, identificar as possibilidades de aplicação de práticas de educação ao ar livre para o desenvolvimento destas. Refletimos sobre a forma como a educação ao ar livre permite a construção de competências geográficas e transformações pessoais, e apresentamos através de atividades as potencialidades dessas práticas.
O trabalho de campo de geografia escolar como ferramenta de ressignificação do lugar para estudantes periféricos: uma proposta a partir do bairro carioca de Santa Cruz
Authors: Pimenta José Renato Soares
Published: April 2021

A importância do trabalho de campo para a Geografia é inconteste. Na Geografia Escolar o trabalho de campo permite ganho num processo de ensino-aprendizagem que busque a aprendizagem significativa, pois abrem-se como possibilidades a averiguação de conceitos abordados em sala de aula, a complexificação da visão de mundo, a ressignificação do lugar, entre outras. Este trabalho tem por objetivo analisar o trabalho de campo de Geografia como procedimento didático que busque a ressignificação do lugar para alunos residentes em áreas periféricas, bem como elaborar uma proposta de uma sequência de trabalhos de campo no bairro de Santa Cruz, localizado no extremo oeste do município do Rio de Janeiro. Tais escolhas de recortes se deram por este autor atuar como professor do Ensino Fundamental numa escola da rede pública na área em tela. A relevância desta pesquisa encontra-se na concepção do trabalho de campo como prática espacial insurgente de ressignificação do lugar, aumentando o sentimento de pertencimento, aguçando o pensamento crítico e empoderando-os com a noção de que suas ações espaciais podem melhorar a qualidade de vida deles próprios e de suas comunidades.
Türkiye’de Sektörel Enerji Kullanımındaki Değişimlerin İtici Güçleri: Ayrıştırma Analizi
Authors: TÜRKÖZ Kumru
Published: April 2021

Bu çalışmada, 1970-2018 döneminde ekonomik ve demografik yapısında önemli değişiklikler meydana gelen Türkiye’de sektörel enerji kullanımındaki değişikliklerin itici güçlerini incelemek amaçlanmaktadır. Buradan hareketle çalışmada, bu değişikliklerin tarım, sanayi, konut ve hizmetler ile ulaştırma gibi birincil sektörlerdeki enerji kullanımı üzerindeki etkileri toplamsal tipte ayrıştırma analizi (Logarithmic Mean Divisia Index [LMDI]) yöntemi kullanılarak araştırılmaktadır. Analiz sonuçları; incelenen dönemde ortalama olarak sektörel enerji kullanımının her bir sektörde çıktı etkisi ile arttığını, tarım sektörü hariç diğer sektörlerde ise yoğunluk etkisi ile azaldığını göstermektedir. Diğer bir ifade ile çıktı etkisi üretim artışı kanalıyla sektörel enerji kullanımı üzerinde yoğun bir etkiye sahipken, yoğunluk etkisi sektörlerdeki enerji yoğunluğunun kısmen düşme eğilimi içinde olması nedeniyle sektörel enerji kullanımı üzerinde düşürücü bir etki yaratmaktadır. Yapısal etki ise tarım ve sanayi sektörlerinde enerji kullanımını düşürücü, konut ve hizmetler ile ulaştırma sektörlerinde ise enerji kullanımını arttırıcı etki yaratmaktadır. Sektörlerin enerji kullanımlarında meydana gelen bu etkilerin farklılaşmasının, incelenen dönemde meydana gelen yapısal dönüşüme bağlı olarak ülkenin izlediği ekonomi politikalarının farklılaşmasından kaynaklandığı düşünülmektedir.
Çevre Etiği Bağlamında Medyanın Çevre Sorunlarına Yönelik Sorumluluğu: Kırgızistan Gazeteleri Örneği
Authors: YOĞURTÇU Gökçe
Published: April 2021

Doğayı koruma ve onu gelecek nesillere sağlıklı bir şekilde bırakma sorumluluğu, etik değerlerin ve siyasetin kurucu unsurlarından biri haline gelmiştir. Bu sorumluluğun farkına varılması tüm dünya ülkeleri için olduğu gibi Kırgızistan için de önemlidir. Kırgızistan coğrafi konumu gereği çeşitli çevresel riskler altındadır. Bu sorunlara yönelik farkındalık yaratmak ve çevre politikalarına yön vermek açısından medyanın potansiyel bir güç olması beklenmektedir. Bu çalışmanın amacı da Kırgızistan basınının çevre sorunlarına ilişkin halkı bilgilendirme ve farkındalık yaratma sorumluluğuna dikkat çekmektir. Bu amaçla araştırmada, Kırgızistan’daki çevre sorunlarının basına nasıl yansıdığı sorusuna yanıt aranmıştır. Analiz kapsamında Kırgızistan’ın tirajı en yüksek kamu gazetesi olan “Kırgız Tuusu” ve tirajı en yüksek özel gazetesi olan “Süper İnfo” gazeteleri örneklem olarak seçilmiştir. Bu gazetelerin internet sitelerinde 1 Temmuz 2019 – 01 Temmuz 2020 tarihleri arasında yer alan çevre sorunlarıyla ilgili toplam 103 haberin “içerik analizi” yapılmıştır. Elde edilen bulgular; gazetelerin çevre sorunlarına “insan merkezli” yaklaştığını ve çevre haberciliği perspektifinin yetersiz olduğunu göstermektedir.
Удосконалення технології отримання пектинового концентрату з вичавків червоного буряку для медичної та фармацевтичної промисловості
Authors: Бушуєв А.С. , Шапкін В.П. , Мороз О.В. , Котова В.В.
Published: April 2021

Проведені дослідження по створенню удосконаленої і безвідходної технології отримання стійкого до окислення харчового бурякового пектину з його вичавків для медичної та фармацевтичної промисловості, а також виробництва хлібобулочних і кондитерських виробів, желейного мармеладу тадиєтичних  продуктів харчування, що дозволили скоротити тривалість технологічного процесу з одночасним зменшенням енерговитрат. Удосконалена технологія отримання пектину в порівнянні з відомими технологіями, яка відрізняється безвідхідністю і екологічністю, так як в екстракції використовуються в якості екстрагента дешева лимонна кислота в невеликих концентраціях, що отримується при переробці лимонів в соки, а також для виділення пектину застосовується відновлений дистиляцією етиловий спирт. Оптимізовано умови екстракції пектину з бурякового жому, що дозволяють отримати пектин з виходом до 30%, який відповідає даним з літературних джерел. Показано, що неутилізуємі відходи від екстракції пектину використовуються для біопалива або для технологічних потреб у виробництві матеріалів медичного призначення.
Моделювання аварій та дослідження ризиків при зберіганні зріджених вуглеводневих газів за допомогою програмного комплексу «Різекс-2»
Authors: Король Д.Р. , Грановський Е.О. , Глікіна І.М. , Глікін М.А.
Published: April 2021

У статті розглянуто питання щодо оцінки небезпеки, яка може виникнути при зберіганні зріджених вуглеводневих газів. Оцінку виникнення аварійних ситуацій, розвитку аварійних ситуацій та розміри вражаючих факторів, які потенційно можуть завдати шкоду людині, зроблено за допомогою програмного комплексу «Різекс-2». Виконано розрахунок ризику, вражаючих факторів різних сценаріїв розвитку аварійної ситуації.
Про використання відходів водопідготовки в якості вторинної сировини для виробництва мінеральних, органо-мінеральних та органічних добрив
Authors: Кузенна А.О. , Канарова К.І. , Корчуганова О.М.
Published: April 2021

Розробка нових ефективних добрив останнім часом є одним з актуальних напрямків розвитку агрохімії. Водночас, зменшення кількості накопичених відходів, озеленення технології виробництва, відповідає цілям сталого розвитку. Метою роботи було встановлення можливості комплексного використання відходів водопідготовки, які є одним з видів багатотоннажних відходів промисловості. В статті розглянуто потенціальні можливості використання відходів водопідготовки в ефективні органо-мінеральні добрива, розглядаються можливості використання всіх складових відходів.
Вплив кавітаційної обробки гексану та пентану одноатомними спиртами
Authors: Кудрявцев С.О. , Леоненко С.В. , Целіщев О.Б. , Лорія М.Г. , Пономарьов С.О.
Published: April 2021

На сьогоднішній день попит  світлі нафтопродукти а саме бензи, з великою швидкістю збільшується не зважаючи кількості попиту на дизельне палив та альтернативні види палив. У статті представлено загальне поняття компаундування, поняття гідродинамічної кавітації та інші види кавітації. Були проведені дослідження гідродинамічної кавітації на обробку модифікованого гептану та гексану одноатомними спиртами та вплив на значення їх детонаційної стійкості. Експериментально було доведено що кавітація впливає на збільшення октанового числа вуглеводнів модифікованих одноатомними спиртами на 4,5-4,6 пункти при концентрації спирту не більше 1 %.
Pevonedistat and azacitidine upregulate NOXA (PMAIP1) to increase sensitivity to venetoclax in preclinical models of acute myeloid leukemia
Authors: Cojocari Dan , Smith Brianna N. , Purkal Julie J. , Arrate Maria P. , Huska Jason D. , Xiao Yu , Gorska Agnieszka , Hogdal Leah J. , Ramsey Haley E. , Boghaert Erwin R. , Phillips Darren C. , Savona Michael R.
Published: April 2021

Dysregulation of apoptotic machinery is one mechanism by which acute myeloid leukemia (AML) acquires a clonal survival advantage. B-cell lymphoma protein-2 (BCL2) overexpression is a common feature in hematologic malignancies. The selective BCL2 inhibitor, venetoclax (VEN) is used in combination with azacitidine (AZA), a DNAmethyltransferase inhibitor (DNMTi), to treat patients with AML. Despite promising response rates to VEN/AZA, resistance to the agent is common. One identified mechanism of resistance is the upregulation of myeloid cell leukemia-1 protein (MCL1). Pevonedistat (PEV), a novel agent that inhibits NEDD8-activating enzyme, and AZA both upregulate NOXA (PMAIP1), a BCL2 family protein that competes with effector molecules at the BH3 binding site of MCL1. We demonstrate that PEV/AZA combination induces NOXA to a greater degree than either PEV or AZA alone, which enhances VEN-mediated apoptosis. Herein, using AML cell lines and primary AML patient samples ex vivo, including in cells with genetic alterations linked to treatment resistance, we demonstrate robust activity of the PEV/VEN/AZA triplet. These findings were corroborated in preclinical systemic engrafted models of AML. Collectively, these results provide rational for combining PEV/VEN/AZA as a novel therapeutic approach in overcoming AML resistance in current therapies.
Study Design in Medical Research
Authors: Choudhury Shahnaz , Amin Md Nurul
Published: April 2021

An appropriate study design is key to answer the research question or to test the hypothesis of a study. A study design is, in fact, how a study can be conducted in a given situation. A study design is more important than analysis of data, for a faulty study design can never be retrieved once it is applied, whereas a poorly analysed study can be retrieved and reanalyzed if needed. Therefore, appropriate study design is an effective way to draw a meaningful conclusion from the research data. Here we highlight the key concept of study design, their types and formulating a study design based on research question and hypothesis.

Ibrahim Cardiac Med J 2012; 2(2): 41-47
Outcome of Early Disposal of Lower Uterine Caesarean Section Patient from Hospital - A Randomized Clinical Trial
Authors: Moon Moon TH Johra , Begum Kohinoor , Sharmin Sabina , Begum Zinat
Published: April 2021

Background and Objectives: Uncomplicated caesarean section patients are usually discharged from the hospital on the 7th postoperative day. Prolonged hospital stay increases the chance of nosocomial infections and facilitates them to spread rapidly. Experience shows that early discharge of patients reduces the chance of maternal and neonatal morbidities. The present study was done to assess the outcome patients discharged early from the hospital following caesarean section.

Patients & Methods: The present randomized clinical trial was conducted in Dhaka Medical College Hospital, Dhaka Bangladesh from July 2006 - December 2006. A total of 300 term pregnant women admitted consecutively in the Obstetrics & Gynaecology Department of the Hospital and underwent elective or emergency caesarean section were included in the study. The patients were randomly divided into two study groups - early discharge group and usual discharge group. Patients of Group-A were discharged 72 hours after caesarean section and were advised to visit after 7th postoperative day for follow up, while the patients of Group-B stayed in the hospital for 7 days (including the day of operation) and outcome was evaluated on 7th postoperative day at discharge. The maternal outcome measures were urinary and respiratory tract infections (UTI and RTI), wound infection and puerperal sepsis and neonatal outcome variables were umbilical cord sepsis, septicemia and respiratory distress syndrome.

Results: Of the 4,494 labour patients admitted during the 6 months study period, 1744(38%) needed caesarean section. Of them, 300 consecutive cases fulfilling the enrolment criteria were included in the study. The demographic variables studied were age, parity, socioeconomic condition. Types of caesarean section (elective or emergency) were also recorded. In 'Early discharge group' (discharge on 3rd postoperative day) out of 150 patients, only 50 patients returned for follow up on 7th postoperative day. Majority (84%) of them was free from any sorts of complications and very few of their neonates have had any complications. In 'Usual discharge group'(discharge on 7th postoperative day) out of 150 patients, 69(46%) cases developed complications. Of them wound infection was the leading complication (36%) followed by UTI (16%), RTI (9.3%), puerperal sepsis (8.0%), wound dehiscence (6.7%). Umbilical cord sepsis of newborn was also significant (17.3 %) in them. Other complications were considered negligible. Occurrence of overall complication was staggeringly lower in the former group than that in the later group (8% vs. 46%, p < 0.001).

Conclusions: Early discharge of patients of caesarean delivery from hospital is safe for both mothers and neonates. It reduces unnecessary hospital burden and saves hospital resources.

Ibrahim Cardiac Med J 2014; 4(1): 22-26