bluuebunny/crossref_metadata_2025 huggingface dataset:
Producción de pigmentos procedentes de Arthrospira maxima cultivada en fotobiorreactores
Authors: Romero Maza Lolymar De los Ángeles , Guevara Miguel Ángel , Gómez Bladimir José , Arredondo-Vega Bertha , Cortez Roraisy , Licet Berenice
Published: June 2017

El cultivo de cianobacterias, como Arthrospira, puede realizarse en sistemas abiertos y sistemas cerrados o fotobiorreactores. El objetivo de la presente investigación fue evaluar la producción de pigmentos de Arthrospira maxima cultivada en dos tipos de fotobiorreactores. El cultivo se realizó de forma discontinua (Batch) bajo ambiente controlado, en fotobiorreactores helicoidales y cilíndricos, durante 30 días, en medio Zarrouk. La determinación de los pigmentos se realizó en las fases de crecimiento exponencial y estacionario. Para los pigmentos liposolubles, la biomasa se sometió a extracción con acetona 90%, y posterior determinación por Cromatografía Líquida de Alta Eficiencia, y para la extracción de los pigmentos ficobiliproteínicos se ensayaron cuatro métodos: 1. regulador de fosfatos/enzimas; 2. solución alcalina, previo tratamiento con CaCl2; 3. buffer de fosfato, previo tratamiento con hielo seco y 4. agua (4ºC), y posterior determinación por Espectrofotometría UV-Visible. Los mayores valores de pigmentos liposolubles fueron obtenidos en los cultivos realizados en fotobiorreactor helicoidal durante la fase exponencial (clorofila a 11,08±0,006 µg mL-1; β-caroteno 1,82±0,003 µg mL-1; zeaxantina 0,72±0,002 µg mL-1); mientras que los mayores contenidos de los pigmentos ficobiliproteínicos se obtuvieron en fotobiorreactor cilíndrico, durante la fase estacionaria, utilizando el buffer de fosfato tratado con hielo seco para la extracción. Dentro de las ficobiliproteínas, fue la ficocianina la que se encontró en mayor proporción (FC = 77,74±0,767 mg L-1), seguido por la aloficocianina y ficoeritrina. Se concluye que la biomasa de Arthrospira maxima presenta potencial biotecnológico por sus altos contenidos de pigmentos.
Regeneración in vitro de plantas de piña (Ananas comosus) ecotipo amazónico Gobernadora
Authors: Blanco Flores Héctor Alexander , Vargas Cedeño Teresa Edith , García de García Eva Cristina
Published: June 2017

En Venezuela existen cultivares y ecotipos de piña (A. comosus) de importancia local, entre ellos los amazónicos, cultivados principalmente por los aborígenes Piaroa. Ellos siembran los propágulos lo cual restringe la disponibilidad de material para el cultivo a gran escala. Se abordó la limitación recurriendo al cultivo de tejidos vegetales para la propagación in vitro de plantas de piña, ecotipo amazónico Gobernadora, mediante embriogénesis somática (ES) y organogénesis adventicia (OA). El material vegetal empleado correspondió a secciones basales e intermedias de hojas. Sólo las secciones de base foliar (SBF) fueron morfogénicamente inducidas. El mayor número de vitroplantas (1,58 plantas/explante) se obtuvo del callo embriogénico inducido en medio MS con Picloram 10 mg.L-1 + Tidiazuron 2 mg.L-1, transferido a MS sin hormonas. En el proceso organogénico, se obtuvo el mayor número de plantas/explante (5) por vía directa en MS con ácido naftalenoacético 5 mg.L-1 + bencilaminopurina 0,25 mg.L-1, transferido a MS. Siendo este último el mejor sistema de cultivo in vitro por su productividad y por ser una ruta que minimiza la variación somaclonal.
The Evaluation and Management of Fetal Growth Restriction
Authors: Ryu Aeli
Published: June 2017

Fetal growth restriction (FGR) occurs due to various reasons and is associated with increased fetal and neonatal mortality and morbidity. FGR has been defined as having birth weight less than the 10th centile. The first clinically relevant step is the detection of true FGR, pathological small fetuses, associated with signs of abnormal placental insufficiency and poorer perinatal outcome. The role of obstetric management is to identify growth restricted fetuses at risk of chronic hypoxia in uterus, to monitor their wellbeing, and to deliver when the adverse outcome is imminent. The purpose of this document is to review the FGR with diagnosis, antenatal surveillance tools, and guidance for management and timing of delivery.
Clinical Features of Patients with Congenital Hypothyroidism Due to Ectopic Thyroid
Authors: Kang Heejeong , Lee Jeongho , Lee Dong Hwan
Published: June 2017

Objective: This study aimed to describe the clinical features of patients with congenital hypothyroidism due to ectopic thyroid including locations of ectopic thyroid, thyroid function, age of treatment, and starting dose of medication. Methods: A total of 71 children with congenital hypothyroidism due to ectopic thyroid diagnosed by thyroid ultrasonography (USG) or 99mTc-petechnetate thyroid scan in the department of pediatrics, Soonchunhyang University Seoul Hospital from 1992 to 2015 were enrolled and analyzed retrospectively. Results: Among 71 patients, 26 patients (36.6%) were male and 45 patients (63.4%) were female as the gender ratio was 1:1.73. The locations of ectopic thyroid confirmed by USG or scan were found to be sublingual in 52 patients (73.2%), lingual in 17 patients (23.9%), prelaryngeal in 1 patient (1.4%), and combined in 1 patient (1.4%), respectively. The average value of serum thyroid stimulating hormone was 267.5 μIU/mL and free thyroxin was 0.63 ng/dL. The average value of thyroglobulin (TG) was 217.6 ng/mL. Fifty two patients (73.2%) started treatment within the 1 month of age and 19 patients (26.8%) started after the 1 month of age. The average of the medication starting dose was 12.2 μg/kg/day. There was no significant difference on TG value and starting medication dose. Conclusion: As the previous literatures, the presence of ectopic thyroid was more common in female than male. It was coincident with this study. It is generally accepted that lingual ectopic thyroid is most common ectopic location, but in this study, proportion of sublingual thyroid was most common.
The Effect of Different Oxygen Flow Rates via Nasal Cannula in Recovery Room after Pectus Excavatum by the Nuss Procedure
Authors: Seo Yonghan , Chung Jin Hun , Jeong Minyoung , Gong Hyungyoun
Published: June 2017

Objective: In pectus excavatum patients, Nuss procedure provides excellent cosmetic results, but it cause hypoxemia and hypercarbia by the reduction of alveolar ventilation due to severe thorax expansion and pain after operation. This study was designed to evaluate the effect of different oxygen flow rates via a nasal cannula in recovery room after correction of pectus excavatum by Nuss procedure. Methods: Forty patients (3–12 years old) undergoing pectus excavatum repair were randomly assigned and divided into two groups. Patients were given 200 mL/kg/min flow of 100% oxygen (group 1) and 100 mL/kg/min flow of oxygen (group 2) via nasal cannula in the recovery room. Arterial blood gas analysis and peripheral oxygen saturation were measured at arrival and after 5, 10, 15, and 30 minutes in the recovery room. Results: In group 1 compared with group 2, decrease of PaCO2 (partial pressure of CO2 in arterial blood) accumulation was observed in 5, 10, and 15 minutes. Arterial oxygen pressure (PaO2) difference was not significant between the group. But, in comparison within groups, PaO2 level was significantly higher at 5, 10, 15, and 30 minutes than just after arrival at the recovery room. In both group, heart rate and systolic blood pressure were no significant difference. Conclusion: We recommend that 200 mL/kg/min flow of 100% oxygen should be administered to patients who were taken Nuss procedure for prevention of hypoxemia and hypercarbia in recovery rooms.
Risk Factors for Persistent Storage Symptoms after Holmium Laser Enucleation of Prostate
Authors: Yang Heejo , Chang Sanghoon , Jeon Younsoo
Published: June 2017

Objective: Holmium laser enucleation of prostate (HoLEP) is as fast-paced treatment that is one of the standard treatment for benign prostate hypoplasia. However, there is a rare case that the satisfaction rate of surgery is lowered due to storage symptoms such as frequency and urgency. We investigated the risk factors of bladder irritation symptoms persisted after holmium laser enucleation of prostate. Methods: From January 2009 to December 2014, 220 patients underwent HoLEP in Soonchunhyang University Cheonan Hospital. Among them, 133 patients were selected who did not have any problem that could affect the voiding function including urologic cancer, neurogenic bladder, urinary tract infection, and bladder stone disease. At 3 months after surgery patients were divided into two groups: postoperative International Prostate Symptom Score (IPSS) storage symptom scores <8 (group I) and ≥8 (group II). The two groups were analyzed the parameters: preoperative (prostate size, uroflowmetry, IPSS, prostate calcification), intraoperative (operative time, resected prostate weight), and postoperative (IPSS, uroflowmetry). Results: Of the 133 patients, 94 patients were assigned to group I and 39 patients were group II. Age of the patients, the prostate size, and maximal urinary flow rate showed no statistical difference in both groups. Preoperative storage symptom scores were significantly higher in group II (P<0.05) and IPSS voiding-to-storage subscore ratio was lower in group II without significance (P<0.05). The prostate calcification, periurethral prostatic calcification, and intravesical prostatic protrusion was no difference in the two groups. Postoperative IPSS, maximal urinary flow rate, and post-void residual urine volume was improved in two groups but storage symptom score was not improved in group II. Operative time and resected prostate weight were not found the differences, and postoperative parameters (maximal urinary flow rate, post-void residual urine volume) were showed no difference in both groups. However all of the IPSS was higher in group II. Conclusion: Many symptom improvements after HoLEP were observed but some patients may have difficulties due to persistent bladder irritation. Because bladder irritation sign could persist after surgery if preoperative storage symptom score was higher, it is necessary for a detailed description before surgery.
Comparison of Clinical Features between Noroviral and Rotaviral Gastroenteritis
Authors: Song Jee In , Park Min Jee , Lee Yoo Min , Kim Chun Dong , Lee Hee Kyung , Kim Sung Soo , Lee Jong Hyun
Published: June 2017

Objective: Rotavirus and norovirus are the most common pathogens causing acute gastroenteritis in children. As the incidence of noroviral gastroenteritis increases, it is becoming more important to identify the clinical features of noroviral infection. We compared the clinical features of noroviral gastroenteritis and rotaviral gastroenteritis. Methods: This study included 79 children with noroviral and 151 children with rotaviral gastroenteritis, who were admitted to the Soonchunhyang University Gumi Hospital between January 2013 and December 2014. We reviewed their medical records and compared the clinical features of gastroenteritis between the two groups respectively. Results: In those belonging to the norovirus group, the mean age was 29.65 months, which was younger than that of the rotavirus group, at 34.74 months. Patients suffering from noroviral gastroenteritis experienced more vomiting (5.6 episodes/day) than diarrhea (3.5 episodes/day). Vomiting, diarrhea, and fever were all less severe in those suffering from noroviral gastroenteritis. It is commonly noted that patients with noroviral infection have vomiting and diarrhea without fever (55.0%), while those with rotaviral infection present with vomiting, diarrhea, and fever (44.3%). Conclusion: Although noroviral gastroenteritis is less severe than rotaviral gastroenteritis, the incidence of noroviral infection is increasing, and the mean age group infected with this virus is getting younger; thus, noroviral infection must be considered in the differential diagnoses in young patients with gastroenteritis.
Four Consecutive Recurrent Abortions in Patient with Essential Thrombocythemia
Authors: Seo Hui-Gyeong , Park Haena , Jeon Hye-Ji , Kim Yun-Sook
Published: June 2017

Essential thrombocythemia (ET) is characterized by most cases in which platelet counts exceed 1 million/μL. ET is usually no symptoms during non-pregnancy, but arterial and venous thrombosis and hemorrhage may develop in pregnancy. Pregnancy in these patients is associated with many complications in both pregnant women and fetuses such as recurrent abortion, intrauterine fetal growth restriction, preterm delivery, preeclampsia, and stillbirth. In these patients, aspirin, low-molecular-weight heparin (LMWH), and interferon alpha (INF-α) are recommended during pregnancy. We report a case of four consecutive abortions despite being treated with INF-α, low dose aspirin, and LMWH in patient with ET.
Posterior Reversible Encephalopathy Syndrome Following Meningitis in Pregnancy
Authors: Park Haena , Kim Yun-Sook
Published: June 2017

Posterior reversible encephalopathy syndrome (PRES) is a clinical-neuroradiological entity characterized by headache, vomiting, mental change, and seizures as well as images suggesting leptomeningeal edema involving in most cases posterior regions of the brain, as proven by magnetic resonance imaging. PRES occurred in association with severe infection, autoimmune disease, post-chemotherapy, and preeclampsia-eclampsia. Meningitis is an inflammation of the meninges. The most common causes of meningitis are viral and bacterial infections. While PRES is usually reversible, the early recognition and treatment of this syndrome is important to prevent permanent neurological disorders. The treatment is elimination of causal factors. We report a rare case of PRES after meningitis during pregnancy being treated with medical and rehabilitation treatment.
Isolated Unilateral Hypoglossal Nerve Palsy Following Transoral Endotracheal Intubation for Endoscopic Sinus Surgery
Authors: Shin Jinsub , Cho Sung Hwan , Koo Bon Sung , Chung Yang Hoon
Published: June 2017

Hypoglossal nerve palsy is a rare complication of endotracheal intubation. The mechanism of nerve palsy is mainly attributed to stretching or compression of the nerve during airway manipulation. The cuff pressure can also contribute to the occurrence of hypoglossal nerve palsy. Since it is often accompanied by other cranial nerve palsies, meticulous overall cranial nerve examination is necessary. The main treatment is supportive with respiratory monitoring. The prognosis is favorable. Majority of patients achieve nearly full recovery of nerve function. Here, we report a case of unilateral hypoglossal nerve palsy following usual, uneventful endotracheal intubation and review the literature.
Brain Stem Infarction Due to Basilar Artery Dissection in a Patient with a Parotitis and Hyperhomocysteinemia
Authors: Ahn Byoung June
Published: June 2017

A 29-year-old man developed sudden dysarthria and right-sided weakness 3 days before admission to hospital. He was diagnosed with parotitis in the emergency room of Soonchunhyang University Gumi Hospital. The plasma levels of homocysteine were elevated (30.48 mg/dL). A brain magnetic resonance imaging scan revealed a high signal intensity lesion in the left paramedian pons and computed tomography angiography showed a marked narrowing of the mid-basilar artery. We report a rare case of spontaneous basilar artery dissection caused by a recent infection and hyperhomocysteinemia.
Adrenal Tuberculosis Mimicking a Malignant Tumor with Primary Adrenal Insufficiency
Authors: Kim Woo Seok , Lee Jin Hyung
Published: June 2017

Adrenal tuberculosis is a relatively infrequent cause of primary adrenocortical insufficiency in developed countries. Isolated adrenal tuberculosis, especially with enlargement of adrenal glands, can cause diagnostic problems and requires differentiation from primary or secondary neoplasms. A 40-year-old woman presented to Soonchunhyang University Gumi Hospital with altered consciousness. She showed biochemical evidence of adrenal insufficiency without signs of tuberculosis. Abdominal computed tomography (CT) scan showed a calcified mass 3.3×2.3 cm in size and peripheral enhancement of the left adrenal gland. A laparoscopic adrenalectomy was performed for a diagnosis of left adrenal malignant tumor. The diagnosis of adrenal tuberculosis was confirmed by a final histological examination.
Ovarian Squamous Cell Carcinoma Associated with Endometriosis: Poor Response to Chemotherapy
Authors: Jeon Seob
Published: June 2017

The occurrence of ovarian squamous cell carcinoma associated with ovarian endometriosis is extremely rare. Several studies revealed poor prognosis for ovarian squamous cell carcinoma especially when associated with endometriosis. We report a case of ovarian squamous cell carcinoma that invades the parametrium that is also associated with ovarian endometriosis. A 41-year-old woman with stage IIB ovarian squamous cell carcinoma was treated with debulking surgery followed by six courses combination chemotherapy composed of paclitaxel and carboplatin. Twenty months after the last course of chemotherapy (3 months after normal positron emission tomography–computed tomography [CT] scanning), upper abdominal pain developed and abdomen CT scan revealed multiple metastasis in liver and paraaortic lymph node. Although two cycles of paclitaxel and cisplatin was administrated, she died of disease three months after the recurrence.
Ruptured Tubal Pregnancy with Massive Retroperitoneal Hemorrhage
Authors: Mun Seong Taek , Ryu Aeli
Published: June 2017

Ectopic pregnancy is an implantation of the fertilized ovum on a place except the endometrium. Most of the ectopic pregnancies are located at the fallopian tube. Few cases of retroperitoneal hematoma associated with ectopic pregnancy have been reported on previously; in each the retroperitoneal space had been the site of implantation. In contrast, we treated a patient with an ectopic pregnancy that implanted in the tube and then perforated through into the retroperitoneal space. To our knowledge this is very rare case of retroperitoneal hematoma caused by a ruptured tubal pregnancy.
Acute Sheehan’s Syndrome Associated with Postpartum Hemorrhage
Authors: Kim Deokkyeong , Min Jiwon , Kim Yun-Sook , Ryu Aeli
Published: June 2017

Sheehan’s syndrome is postpartum hypopituitarism due to the necrosis of the pituitary gland. Usually, it is the result of severe hypotension caused by massive hemorrhage during or after delivery. A 40-year-old woman who had been performed cesarean section delivery was complicated by hemorrhage due to uterine atony. After transfusion and hysterectomy, she is gradually recovering her general condition. On 16th day after operation, she visited emergency room in critical condition with nausea, vomiting, and general weakness and laboratory finding was hyponatremia. So, we medicated her with hydrocortisone and thyroxine. Sheehan’s syndrome should be considered in the differential diagnosis of hyponatremia in the early postpartum period.
Broken Metallic Intubation Stylet after Tracheal Intubation in Pediatric Patient
Authors: Jung Ho-Soon , Kang Jin-Ku
Published: June 2017

A 6-year-old male patient underwent general anesthesia for laparoscopic appendectomy. During induction of intubation, metallic intubation stylet was broken. Broken piece was confirmed by bronchoscopy and chest radiography and was rapidly removed using a surgical forceps. The patient was discharged on the fifth postoperative day without any adverse effects.
Delayed Recovery of Motor Block Following Radiofrequency Ablation of Varicose Veins with Femoral Nerve Block and Tumescent Anesthesia
Authors: Jun Mi Roung , Kim Young Eun , Yoon Sang Chul , Kim Mun Gyu
Published: June 2017

Femoral nerve block with tumescent anesthesia is used to perform the radiofrequency ablation of varicose veins. The surgery can be done as day-case. But if recovery from motor block is delayed, it can make hospital discharge difficult. Prolonged femoral nerve blocks with motor blockade of the quadriceps have been noted after the use of bupivacaine. The motor blockade lasted up to 30–40 hours when 15–30 mL of 0.5% bupivacaine was used. However, it was rarely reported in ropivacaine. We report that femoral nerve block with 15 mL of 0.375% ropivacaine induced prolonged motor blockade up to 30 hours.
Pneumomediastinum and Pneumoretroperitoneum Induced by Foreign Body in Bronchus
Authors: Bang Hyunho , Kim Seung Soo
Published: June 2017

A 5-year-old boy was on medication after diagnosed with infantile spasm, and had regular diet with bedridden state. The patient had intermittent fever and cough lasting 1 week before admission. Symptom was worsened from the night before the first day of admission, and chest swelled up on the day of admission. Chest computed tomography (CT) was performed and showed extensive subcutaneous emphysema in neck, thorax, and abdomen. Pneumomediastinum, pneumoretroperitoneum, and right lung atelectasis was accompanied. An emergency bronchoscopy was performed because of the suspicion of complete obstruction of left main bronchus. The distal part of left main bronchus was completely obstructed by multiple polypoid masses. The mass was removed with a laser incision, and a foreign body surrounded by mucus was found. It was removed with a forceps. At 2 days after the removal, the subcutaneous emphysema was improved, and the chest CT taken 14 days later showed stenosis but no obstruction.
Rosai-Dorfman Disease of 4-Year-Old Girl
Authors: Gang Jun Seak , Kim Young-Chang , Lee Young Man , Cho Junhun , Suh Won Suk , Park Kyeong Bae
Published: June 2017

Rosai-Dorfman disease also known as sinus histiocytosis with massive lymphadenopathy is a benign, rare systemic disease characterized by a histiocyte proliferation which presents with lymphadenopathy. We report a case of a 4-year-old girl who presented with recurrent cervical lymphadenopathy with tenderness, without any other symptoms. After 1 month of medical treatment, her lymphadenopathy still remained, so we performed complete excision and biopsy. She was diagnosed on cytology as a case of Rosai-Dorfman disease. She responded well to become asymptomatic without recurrence by 1 month.
Polineuropatia, Hepatoesplenomegalia, Gamapatia monoclonal e Plasmocitoma
Authors: Pessuti Fernando , Fontes Cristina Asvolinsque Pantaleão , Ferri Lucila Pessuti , Nascimento Vagner Ferreira
Published: June 2017

Homem, 70 anos, com diagnóstico prévio de hipotireoidismo é internado para investigação de quadro clínico de perda de peso significativa (25 Kg em um ano) associada a parestesia bilateral e simétrica em pés, que evoluiu após quatro meses para paresia em membros inferiores e superiores, e posteriormente para fraqueza muscular em membros inferiores nos dois meses seguintes.

Durante a internação foram realizados exames laboratoriais e tomografia computadorizada (TC) de tórax e abdome que gamapatia monoclonal, plasmocitoma em parede torácica direita, hepatomegalia, esplenomegalia, ascite e derrame pleural à direita, assim como pela polineuropatia periférica e perda de peso.
AVALIAÇÃO DO CONSUMO DE DERIVADOS DE TRIGO POR MEIO DE QUESTIONÁRIO DE FREQUÊNCIA DO CONSUMO ALIMENTAR EM MARINGÁ, PR
Authors: Munhoz Raquel Riccomini , Aquino Magda Pires Correa Rivabene , Carvalho Isabelle Zanquetta , Souza Alexandra Perdigao Maia de
Published: June 2017

O trigo é amplamente utilizado na alimentação humana e ocupa o primeiro lugar em volume de produção mundial. Esta pesquisa teve como objetivo avaliar o consumo de derivados de trigo pela população de Maringá, Paraná, e sua correlação com fatores demográficos e estado nutricional. A pesquisa foi de natureza quantitativa com coleta de dados transversal. Foram avaliados 270 indivíduos adultos com idade entre 20 a 59 anos, de ambos os sexos. Os indivíduos foram abordados nos supermercados da cidade de Maringá, Paraná. Utilizaram-se dois questionários para coleta de dados. No primeiro continham perguntas sobre o perfil dos indivíduos entrevistados (sexo, idade, cor, escolaridade, renda familiar, peso, estatura e Índice de Massa Corporal – IMC). No segundo continha o Questionário de Frequência Alimentar Quantitativo (QFA), utilizado para avaliar o consumo de derivados de trigo. As informações de peso e estatura serviram para o cálculo do IMC: peso (kg)/estatura(m)2, e então se detectou o estado nutricional segundo os pontos de corte estabelecidos pela Organização Mundial da Saúde (OMS). As associações entre o consumo de derivados de trigo e fatores demográficos e estado nutricional foram realizadas por meio de análise estatística, para a qual se utilizou o programa Epi Info versão 7.2.0.1. Os dados foram submetidos ao teste de Mann-Whitney (p
Соотношение тревожности и мотивационных диспозиций у лиц с ограниченными возможностями здоровья
Authors: Комолов Олег Евгеньевич
Published: June 2017

В статье проводится краткий обзор и анализ современных исследований по проблеме соотношения тревожности и мотивационных диспозиций у лиц с ОВЗ.
Френсис Фукуяма: ради идеологически нагруженной русофобии все средства хороши
Authors: Ильин Алексей Николаевич
Published: June 2017

В последние годы средства массовой информации Запада проявили себя как средства массовой дезинформации. Одновременно с повышением градуса русофобии в них понижается градус объективности.  В статье разоблачаются теоретические построения Ф. Фукуямы, которые являются необоснованно русофобскими и совершенно противоречащими исторической, политической и геополитической реальности. Делается вывод, что позиция Фукуямы антинаучна и идеологически нагружена. Тотальная безответственность за свои слова давно стала нормой среди многих политических и геополитических аналитиков «цивилизованного» мира.
The long-term outcome of the modified external dacryocystorhinostomy
Authors: Rakhmanov Vyacheslav V , Potemkin Vitaly V , Meshveliani Elena V , Pirgunova Alyona A , Alchinova Aisa S , Morina Ksenia Y , Ageeva Elena V
Published: June 2017

External dacryocystorhinostomy (DCR) is still the gold standard procedure for treating nasolacrimal duct obstruction or chronic dacryocystitis.

Purpose: to evaluate the long-term functional outcome of the modified technique of external dacryocystorhinostomy.

Materials. 55 patients (61 eyes) with lacrimal drainage system disorders who underwent the modified technique of external DCR between 2013-2015 were involved in the study. In this modified procedure of external DCR, anastomosis was created by suturing only anterior flaps of the lacrimal sac and nasal mucosa and excision of the posterior flaps. The mean age of the patients was 65.8 12.38 years (range, 27-87 years), including 47 females and 8 males. The mean follow-up time was 19.4 6.9 months (range, 4-33 months). The success rate was recorded during the follow-up period. Cosmetic result of surgery was interpreted by the patients.

Results. Criteria for surgical success were defined as no or minimal intermittent epiphora, no reflux on lacrimal irrigation postoperatively and a positive functional dye test. The modified external DCR with only anterior flap anastomosis had a success rate of 93.4%. 4 patients (6.6%) had recurrence of epiphora and not patent lacrimal system to irrigation. In our study, the operation time of DCR varies from 25-40 minutes. After surgery 15 of 55 patients (27.3%) described the incision scar as invisible and 3 of 55 patients (5.5%) graded it as very visible, hypertrophic scar. Five of 55 patients (9.1%) were not satisfied with the appearance of the incision.

Conclusion. The present study concludes that modified external DCR with anterior flaps anastomosis only is a simple, less time consuming surgical technique that is easy to perform and the outcome is comparable to conventional DCR.
Effect of crosslinking with riboflavin and ultraviolet a (UVA) on the scleral tissue structure
Authors: Bikbov Mukharram M. , Surkova Valentina K. , Usubov Emin L. , Nikitin Nikolaj A. , Astrelin Mikhail N.
Published: June 2017

Aim. To evaluate the effect of scleral crosslinking with riboflavin and ultraviolet A (UVA) on scleral tissue structure in vitro.

Material and methods. The study was performed on seven porcine cadaver eyes. Two parallel scleral strips were excised from each eyeball; one was subjected to the crosslinking procedure (instillation of 0.1% aqueous solution of riboflavin mononucleotide for 20 min followed by UV irradiation of 3 mW/cm2 for 30 min), and the other was used as control. Scleral structure was evaluated using light (Van Giesons stain) and electron microscopy. Special software was used to perform morphometric analysis of the microphotographs.

Results. As a result of crosslinking, the average packing density of collagen fibers increased by 8.2%, the intermediate space decreased by 5.2%, and the average diameter of collagen fibrils increased by 12%. There were no pathological changes in the scleral structures.

Conclusion. Obtained results confirm the efficacy of scleral crosslinking with riboflavin/UVA in forming additional crosslinks and the safety of the procedure for the scleral tissue.
La escuela para la democracia, arquitectura escolar y II República en Bilbao
Authors: Muñoz Fernández Francisco Javier
Published: June 2017

Con la constitución de la II República, el Estado entendió que la educación era fundamental para asentar la democracia, por lo que emprendió un programa de mejoras en la enseñanza que también influyeron en la forma de concebir la arquitectura escolar, según servicios de una mayor trascendencia social y espacios acordes con ideas pedagógicas más activas. En Bilbao, el resultado de esta política educativa se tradujo en la construcción de un grupo escolar municipal modelo que dio forma a una nueva manera de entender la escuela, según una arquitectura igualmente moderna que marcó las pautas que siguieron otras iniciativas posteriores.
El martiri dels temples a la Diòcesi de Barcelona (1936-1939)
Authors: Elias Cao Carles
Published: June 2017

Reseña de libro
Robert Venturi y el análisis de la arquitectura de Alvar Aalto
Authors: García Escudero Daniel , Bardí i Milà Berta
Published: June 2017

En el año 2012 se han cumplido cincuenta años de la redacción del libro Complexity and Contradiction in Architecture, publicado en 1966, aunque redactado mayoritariamente en 1962. Este artículo aprovecha la efeméride para rescatarlo y focalizar ahora la mirada en la obra de Alvar Aalto, uno de los arquitectos que, en palabras del propio Venturi, más le influyó: “Aalto es para mí la fuente más rica para aprender por su arte y su técnica”. El análisis de Venturi representa una alternativa a la visión “clásica” que se construye sobre Aalto durante los cincuenta, y marca el camino de estudios posteriores.
La maison cachée de Le Corbusier. Hábitat y habitar en rue Jacob, 1917-1934
Authors: Alonso Pereira José Ramón
Published: June 2017

Edificado en condiciones de Ville Radieuse —según expresión de Le Corbusier—, Porte Molitor ha sido siempre considerado el hábitat corbuseriano por excelencia. Ello ha oscurecido otro lugar donde vivió diecisiete largos y fecundos años: la casa apartamento junto a Saint Germain, donde residió entre 1917 y 1934. Es el hábitat desconocido: la maison cachée de Le Corbusier. Esta monografía pretende analizar esta casa escondida en su doble aspecto del hábitat y del habitar. Descubrir el lugar y el espacio donde Le Corbusier vivía y su modo de habitarlo, haciendo de la maison cachée un antecedente del hábitat radieuse.
El relieve de Jorge Oteiza en la planta baja de su vivienda en Irun: escultura, arquitectura y espacio público
Authors: López Bahut Emma
Published: June 2017

Gracias al hallazgo de nuevo material documental, se demuestra la autoría de Jorge Oteiza del relieve en el forjado superior de la planta baja de su vivienda en Irún, hasta ahora desconocido. A partir de esta intervención, se profundiza en la relación del escultor con el mundo arquitectónico en tres aspectos: la aplicación en la arquitectura de conceptos espaciales que descubre previamente en la escultura; la propuesta concreta de un modo de integración del arte y la arquitectura; su consideración como el primer trabajo en el que Oteiza plantea una relación directa con el espacio urbano y su habitante.
La iglesia de San Paolo en Rho (Milán, 1978/90)
Authors: Longhi Andrea
Published: June 2017

Las superficies sinuosas de la iglesia de San Paolo ofrecen una doble cara. Hacia el interior, responden a la articulación de la acción litúrgica; hacia el exterior, se insertan en la trama verde del paisaje periurbano, en el límite entre la ciudad y el contexto rural. Espacio litúrgico y ambiente externo establecen, por tanto, una fuerte relación dinámica: una correspondencia física (de reciprocidad volumétrica entre las paredes cóncavas y convexas), pero sobre todo, una correspondencia visual y lumínica, gracias a las vidrieras polícromas que permiten una dialéctica siempre diversa entre los volúmenes marmóreos de los polos litúrgicos, las superficies blancas que los acogen y la luz coloreada que los ilumina.
José Ignacio Linazasoro. La mirada del orden
Authors: Sainz Gutiérrez Victoriano
Published: June 2017

Reseña de libro
Luis Gil y Cristina Nieto. El asiento como arquitectura. La arquitectura como asiento
Authors: Río Vázquez Antonio Santiago
Published: June 2017

Reseña de libro
Caja de Resonancia. El patio de la casa MMI de Sostres
Authors: Vázquez Díaz Sonia
Published: June 2017

Buscando el distanciamiento radical de la tradición, el patio de la casa MMI se despoja de todo elemento orgánico y renuncia a establecer relaciones visuales tanto con el espacio exterior como entre ámbitos interiores de la casa. Este drástico ensimismamiento resulta aún enigmático para algunos críticos. A través del análisis espacial y perceptivo, en este artículo se exploran los resultados de este hermetismo: alcanzar las máximas cotas de abstracción y preservar la percepción de los fenómenos estéticos más sutiles.
Fibroblast growth factors and their effects in pancreas organogenesis
Authors: Gnatenko D.A. , Kopantzev E.P. , Sverdlov E.D.
Published: June 2017

Fibroblast growth factors (FGF) – growth factors that regulate many important biological processes, including proliferation and differentiation of embryonic cells during organogenesis. In this review, we will summarize current information about the involvement of FGFs in the pancreas organogenesis. Pancreas organogenesis is a complex process, which involves constant signaling from mesenchymal tissue. This orchestrates the activation of various regulator genes at specific stages, determining the specification of progenitor cells. Alterations in FGF/FGFR signaling pathway during this process lead to incorrect activation of the master genes, which leads to different pathologies during pancreas development. Understanding the full picture about role of FGF factors in pancreas development will make it possible to more accurately understand their role in other pathologies of this organ, including carcinogenesis.
Possible involvement of neuronal nicotinic acetylcholine receptors in compensatory brain mechanisms at early stages of Parkinson's disease
Authors: Kryukova E.V. , Shelukhina I.V. , Kolacheva A.A. , Alieva A.Kh. , Shadrina M.I. , Slominsky P.A. , Kasheverov I.E. , Utkin Y.N. , Ugrumov M.V. , Tsetlin V.I.
Published: June 2017

A role of nicotinic acetylcholine receptors (nAChR) in the development of Parkinson's disease (PD) has been investigated using two mouse models corresponding to the presymptomatic stage and the early symptomatic stage of PD. Quantitative determination of nAChR in the striatum and substantia nigra (SN) was performed using the radioactive derivatives of epibatidine, -conotoxin MII, and -bungarotoxin as ligands. The number of ligand-binding sites changed differently depending on their location in the brain, the stage of the disease and the receptor subtype. Epibatidine binding decreased in the striatum to 66% and 70% at the presymptomatic and early symptomatic stages, respectively, whereas in SN a 160% increase was registered at the presymptomatic stage. The -conotoxin MII binding on striatal dopaminergic axonal terminals at the presymptomatic stage decreased by 20% and at the symptomatic stage it demonstrated a further decrease. The increase in -bungarotoxin binding at the presymptomatic stage and a decrease at the early symptomatic stage was observed in the striatum. In SN, the level of -bungarotoxin binding decreased at the presymptomatic stage and kept constant at the symptomatic stage. The significant decrease in the expression of Chrna4 and Chrna6 genes encoding 4 and 6 nAChR subunits was observed in SN at the early symptomatic stage, while a 13-fold increase in expression of the Chrna7 gene encoding the 7 nAChR subunit was detected at the presymptomatic stage. The data obtained suggest possible involvement of nAChR in compensatory mechanisms at early PD stages.
The Impact of Customer Relationship Management and its Significant Relationship to Customers’ Satisfaction in Cooperative Banking (A Case Study of Kangra Central Co-operative Bank)
Authors: Singh Tandon Manvinder , Nath Sharma Narender , Kumar Bhulal Vipan
Published: June 2017

Customer relationship management is the durable and the most effective approach in maintaining and creating relationship with customers. Once this personal and emotional relationship is built, it is very easy for any organization to identify the actual needs of customer and help them to serve them in a better way. Business organization would not flourish until and unless their customers are happy; this is the reason, why Customer Relationship Management (CRM) is so important? In the present competitive business environment attracting and retaining customers is a challenging task for business organization. To grow, businesses do any only need to attract new customers but also to hold on to existing customers. CRM facilitates organization not only to gain customers but also to retain them. It focuses on improving sales and productivity by effectively catering to customer demands, queries and complaints. Though the traditional method of maintaining good customer relations is still being used yet the importance of CRM cannot be neglected. The more effectively a business can use information about its customer to meet their needs the more profitable it would be for the organization. Companies can provide excellent customer service if they are aware about their customers’ needs and react to those needs effectively. CRM helps you to understand, anticipate and respond to your customers’ needs and react in a consistent way. The paper analyses how organization use CRM as a technique to gain business distinction.
Impact Study of Women Empowerment through Self-Help Groups - A Study of Haryana
Authors: Setia Minaxi , Singh Tandon Manvinder , Brijpal ,
Published: June 2017

Women empowerment is emerging as a key challenge for all the communities of a country specially India. In a number of countries, women have to struggle for their rights and living values. To beat such issues various steps have been taken by private, public and non-governmental organizations. A Self Help Group is one of these steps, which is radically contributing in the way of women empowerment. Self Help Groups give opportunities to the poor women to manage their lives through savings along with running small-scale businesses. Numerous studies have been conducted and results show that the Self Help Group is crucial for rural finance services and is also helpful in enhancing work opportunities. The present study is based on quantitative impact analysis of SHGs of Hisar district, state Haryana, India. Data has been collected and analyzed through questionnaires and that was moreover an interview. Target for the respondents were women living in this district who had joined SHGs. Descriptive statistics of this study show the significance of the SHGs in the way of improvement of women’s socio-economic conditions in the district.
Study of Factors Influencing the Stock Prices of Selected IT, Cement and Pharmaceutical Companies in Indian (2011-2016)
Authors: Agnihotri Anurag
Published: June 2017

This paper investigate the factors which influence the stock price of any company with a focus on selected Cement, Pharmaceutical and IT company. The future price of any stock depends on certain factors such as EPS, DPS and PE. The studies explain that dividend and P/E Ratio impact the stock prices but they have not taken the EPS as factor responsible for stock price. So for this paper we have taken three factors EPS, Dividend and Price earnings Ratio as factors which may influence the price of stock with specific reference to Cement, Pharma and IT sector companies. For this research paper, research methodology is exploratory in nature. The statistical tools like correlation and regression were used to analyzed the data. It was observed that EPS, DPS and PE highly correlated to the future price of many companies of different sectors however few are influenced by the PE Ratio.
Speech Recognition using Wavelet based Feature Extraction Techniques
Authors: Sangwan Pardeep , Sheoran Dinesh , Bhardwaj Saurabh
Published: June 2017

Speech recognition by machine may be defined as the conversion of human speech signal into textual form automatically by the machine without any human intervention. Two feature extraction techniques utilizing DWT (Discrete Wavelet Transform) and WPD (Wavelet Packet Decomposition) for speech recognition are discussed in the present article. The comparison of two speech recognizer, first, based on Discrete Wavelet Transform and the second based on Wavelet Packet Decomposition, and with four classifiers has been done in this paper. The proposed method is implemented for a database consisting of ten digits and two hundred speakers, making it a database of 2000 speech samples. The results present the accuracy rate of the respective speech recognizers.
Provide Developing Countries with Free or Low Cost Access to Academic and Professional Peer-Reviewed Content Online- Research4life
Authors: Board Editorial
Published: June 2017

Research4Life is a public-private partnership of the WHO, FAO, UNEP, WIPO, Cornell and Yale Universities, the International Association of Scientific, Technical & Medical Publishers and up to 185 international scientific publishers. The goal of Research4Life is to reduce the knowledge gap between high-income countries and low- and middle-income countries by providing affordable access to critical scientific research. Since 2002, the four programmes – Research in Health (Hinari), Research in Agriculture (AGORA), Research in the Environment (OARE) and Research for Development and Innovation (ARDI) – have provided researchers at more than 8200 institutions in more than 115 low- and middle-income countries with free or low-cost online access to up to 77,000 leading journals and books in the fields of health, agriculture, environment, and applied sciences.
Deskera is a Truly Make in India ERP Software Product Company Developed and Managed by a Group of IITians
Authors: Board Editorial
Published: June 2017

Deskera is a truly make in India ERP Software product company developed and managed by a group of IITians. It is one of the fastest growing ERP business software provider in Asia Pacific. Deskera was recognized as the #1 Integrated Business Applications as a Service (SaaS) provider in the South East Asian market by Frost & Sullivan. Deskera is developed in India at Pune based development Centre – where an expert team of developers and business analysts ensure that world class cloud software is developed, managed and deployed for the entire South East Asian market.
Elderly people and their quality of life – challenges for geography
Authors: Klima Ewa , Janiszewska Anna , Mordwa Stanisław
Published: June 2017

The article raises the issue of the quality of life of elderly people. It focuses on the significance of the phenomenon and possible routes for approaching it within the framework of social geography. The importance of the problem of the quality of life of the elderly is not only a result of demographic conditions related to the increase in the size of this group, but it is also related to the scope of care over elderly people. When describing the quality of life of the elderly, one must refer to four basic categories: (social) communication, health, autonomy and utilisation of institutional services. Studies into the quality of life of the elderly conducted by various scientists help expand the knowledge on this subject and approach these matters from different angles depending on the specific character of each study related to a different area of science. The authors of the study emphasise the role of social geography in this area, not only for explaining the spatial aspects of the phenomenon of the quality of life of elderly people.
Słowa i czyny. O społecznej (nie)odpowiedzialności uniwersytetu
Authors: Rotengruber Przemysław
Published: June 2017

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El lenguaje del juego, de Daniel Sada: ¿Un lugar para observar la violencia?
Authors: Sperling Christian
Published: June 2017

Este artículo analiza críticamente la representación de la violencia en El lenguaje del juego de Daniel Sada. La construcción narrativa de la novela reside en una rígida dicotomía entre la figura idealizada de la familia y los elementos criminales, la cual conduce a la oposición de los dos ámbitos de la normalidad y la anomia. La novela orienta a su lector intencionado con respecto a ambos extremos por medio de guiños metaficcionales, que lo llevan a un “viaje (no) normal” propio del thriller, convención que condiciona el sentido que adquiere la violencia representada. Este artículo contextualiza esta construcción de sentido dentro de las coordenadas del mercado transnacional de libros y del discurso hegemónico sobre los actores criminales en México.
Danaé Torres de la Rosa. Avatares editoriales de un “género”: tres décadas de la novela de la Revolución mexicana. México: Bonilla Artigas Editores/ Instituto Tecnológico Autónomo de México/ Iberoamericana, Vervuert.
Authors: Negrín Edith
Published: June 2017

El presente libro se propone, como describe su título, estudiar el mercado editorial en el que surge y se consolida la novela de la Revolución mexicana. Para llevar a cabo este objetivo central, la autora se plantea varias inquietudes teóricas e históricas fundamentales. La primera, si puede considerarse un “género” ese caudal variopinto conocido como novela de la Revolución.