bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH EMISI OBLIGASI TERHADAP PENDAPATAN SEWA MODAL DENGAN PENDEKATAN MODEL DINAMIS AUTOREGRESSIVE PADA PT. PEGADAIAN (PERSER0)
Authors: Nurulhuda Elly Soraya , Lutfiati Anis , Purnama Oktarian Trisna
Published: February 2022

This study aims to determine the effect of Bond Issuance Value on Capital Lease Income at PT. Pegadaian (Persero). The sample used in this research is the financial statements of PT. Pegadaian that issued bonds in 2007, 2009, 2011, 2012, 2013, 2014, 2015, 2017 and 2018. The independent variable of this study is the value of the bond issuance. The dependent variable is capital rental income. The analysis used is an autoregressive dynamic model with the Koyck approach. The results show that the value of bond issuance and capital lease income from the previous year has a significant effect on capital rental income.
PENGARUH KOMPENSASI DAN MOTIVASI TERHADAP KEPUASAN KERJA KARYAWAN
Authors: Lestari Sri . , Rachmasari Putri
Published: February 2022

This study aims to determine and analyze the Effect of Compensation and Motivation on Employee Job Satisfaction (Case Study at the Kota Kasablanka Branch Paperclip). Collecting data in this study using primary data obtained from questionnaires. The sample in this study were 48 employees of the Kota Kasablanka Paperclip Branch. The analysis technique used is simple regression analysis. Based on the results of the study, partially the compensation variable (X1) has a positive and significant effect on employee job satisfaction (Y) with the results of tcount 4.303> t table 1.679 with t sig 0.000  ttable 1,679 with t sig 0,000> than 0.05. The coefficient of determination means the effect of the contribution between compensation (X1) and motivation (X2) on employee job satisfaction (Y). Testing the coefficient of determination (R2) obtained on the compensation variable on employee job satisfaction is 0.287 or 28.7% while the remaining 71.3% is influenced by other. The coefficient of determination (R2) on the motivation variable on employee job satisfaction is 0.445 or 44.5% while the remaining 55.5% is influenced by other factors.
DETERMINAN PENGHINDARAN PAJAK DENGAN KOMISARIS INDEPENDEN SEBAGAI PEMODERASI PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2015-2019
Authors: Wicaksana Satya Adi , Djaddang Syahril , Darmansyah Darmansyah
Published: February 2022

The study aimed to test the effect of leverage, company size, inventory intensity and liquidity on tax avoidance.In addition, this study also aims to test the influence of independent commissioners who act as moderation. This study was conducted by moderate regression analysis method with sample selection method that is purposive sampling with a sample of 21 manufacturing sector companies during the period 2015-2019.The results showed that leverage positively affects tax avoidance and liquidity negatively affects tax avoidance,while the size of companies and inventory intensity have no influence on tax avoidance.In addition, independent commissioners as moderation strengthen the influence of leverage on tax avoidance.
DAMPAK FAKTOR VOLUME PENAWARAN SAHAM TERHADAP RISIKO SISTEMATIS : PENERAPAN DENGAN REGRESI DATA PANEL METODE COMMON EFFECT (STUDI PADA SAHAM-SAHAM DALAM JII DI BURSA EFEK INDONESIA PERIODE JANUARI – APRIL 2020) KAJIAN STUDI PADA KONDISI PANDEMI VIRUS
Authors: Sunaryo Sunaryo
Published: February 2022

Abstrak. Penelitian ini bertujuan untuk mengetahui dampak Volume Penawaran Saham terhadap Risiko Sistematis. Penelitian ini menggunakan obyek saham-saham dalam kelompok JII (Jakarta Islamic Index) yang terdaftar di Bursa Efek Indonesia (BEI) untuk periode Januari hingga April 2020 dengan sampel jenuh (sensus sampling) sebagai metode. Terdapat 20 saham yang dipilih sebagai sampel. Metode analisis penelitian ini adalah regresi data panel dengan metode common effect. Penelitian menemukan hasil volume penawaran saham berpengaruh positif dan signifikan terhadap risiko sistematis.  

Kata kunci: Volume Penawaran Saham dan Risiko Sistematis
PENGARUH DISIPLIN KERJA DAN PELATIHAN KERJA TERHADAP KINERJA KARYAWAN
Authors: Lestari Sri , Afifah Dilla
Published: February 2022

This study aims to determine the effect of work and training on employee performance (a case study at PT Ardena Artha Mulia in the production section). The number of samples is 50 employees, all of which are respondents in this study. The data technique used a questionnaire, the data were analyzed using the SPSS version 25 program. The analysis performed was regression and regression analysis, coefficient of determination, f test, and t test. Based on the results of hypothesis testing partially work discipline has no effect on employee performance with a significance level of 0,108 > 0,05 and tcount 1,639 < 1,678. Partially job training has a positive and significant effect on employee performance with a significance level of 0,000 < 0,05 and tcount 5,112 > 1,678. The coefficient of determination (R2) for the work discipline variable is 0,317, meaning that it provides a contribution of the influence of work influence on employee performance by 31,7% and the remaining 68,3% from other factors such as: compensation, motivation, leadership style, and others. The coefficient of determination (R2) for the job training variable is 0,536, meaning that it provides a contribution of the effect of training on employee performance by 53,6% and the remaining 46,4% is influenced by other factors such as: work
THE ANALYSIS ON CANONICAL CORRELATION OF GLOBAL INDEX AND MACRO ECONOMY WITH INDONESIAN CAPITAL MARKET
Authors: Amir Afriza , Sadalia Isfenti , Fachruddin Khaira Amalia
Published: February 2022

Capital market is one of the media which gives the opportunity for individual and insttutional investors to invest. The Indonesia Stock Exchange and Indonesian capital market has 11 types of stock priced index which as continously spread through printed and electronic mass media, as one of the guidelines for investor to invest in capital market. The development of indonesian capital market (LQ45 Index and IHSG Index) is closely related to global index and macro economy. The objective of the reseach was to examine the canonical correlation of global index (Dow Jones Index and EIDO Index) and macro economy (Rupiah Exchange Rate and SBI interest rate) with indonesian capital market (LQ45 Index and IHSG Index). The sample were limited to the period of 2011-2013 (36 months).The data were analyzed by using canonical correlation at the significant level of 5%. The result of the research showed that global index (Dow Jones Index and E10) and macro economy (rupiah exchange rate and SBI interest rate) had significant correlation with indonesian capital market (LQ45 and IHSG), with canonical coefficients perfect weight for L045 (1.00) and almost perfect for JCI (0.98). This means that the Dow Jones. EIDO exchange rate, interest rate SBI has a significant positive relationship towards LQ45 Index and IHSG Index are listed on the Indonesia Stock Exchange in the period 2011 to 2013 Individually Dow Jones (0.67), EIDO (0.54) and Exchange Rate (0.37) has a positive relationship with the capital market indices Indonesia (L045 Index and IHSG Index), which means when the Dow Jones. EIDO, and Rupiah Exchange high, then LQ45 and IHSG will be high, or vice versa when the Dow Jones, EIDO, and Exchange Rate is low, then the Index will be lower LQ45 and IHSG. Instead SBI rate (-0.29) had a negative correlation with stock market indices Indonesia (LQ45 Index and IHSG Index), which means if the SBI interest rate is high, then LQ45 and IHSG will be low, or vice versa when the Indonesian interest rate is low, then LQ45 and IHSG will be high
PENGARUH KECERDASAN EMOSIONAL DAN KOMITMEN ORGANISASI TERHADAP KINERJA KARYAWAN PADA PT. RISMAWAN PRATAMA BERSINAR SUKABUMI
Authors: Firmansyah Dery , Raspati Galih , Hidayat Erwin Rinaldy
Published: February 2022

The purpose of this study was to determine the effect of emotional intelligence and organizational commitment on employee performance at PT. Rismawan Pratama Shining Sukabumi. The design in this study uses a survey method with descriptive-quantitative approach and associative methods. To test the analysis of the research instruments used validity test, reliability test and classic assumption test, then to test statistical analysis and relationship analysis used Pearson product moment correlation, coefficient of determination, multiple linear regression and to test the hypothesis used the t test and F test. Based on the results of research that has been done, it can be seen that simultaneously emotional intelligence and organizational commitment significantly influence employee performance. By comparing Fcount with Ftable (183.9719 > 3.10), it means that H0 is rejected and H1 is accepted, so the research hypothesis proposed in this study is proven that emotional intelligence and organizational commitment together (simultaneously) affect the performance of employees. The magnitude of the contribution of the influence of emotional intelligence and organizational commitment to employee performance by 80.5%, while the remaining 19.5% is influenced by variables not examined
EFFECT OF DIVIDEND POLICY (DPR), LIQUIDITY (CR) AND PROFITABILITY ON SHARE PRICE AT TRADE, SERVICE AND INVESTMENT SECTORS AT INDONESIA STOCK EXCHANGE IN PERIOD OF 2014-2018
Authors: Ariesa Yeni , Br. Sitepu Yolanda Pebrina Cristy
Published: February 2022

Stock price is one indicator that shows investor interest in owning a company's stock. An investor always expects a stable stock price and has a pattern of movement that tends to rise from time to time, but in fact the stock price tends to fluctuate. Fluctuating stock prices become a risk for investors. Therefore, an investor must understand the issues that must be considered in determining investment decisions. The research variables are Dividend Payout Ratio (DPR), Liquidity (CR), and Profitability (NPM) and Share Prices. The research populations were Trade, Service and Investment Sector Companies listed on the Indonesia Stock Exchange in 2014-2018. The research samples were drawn by using a purposive sampling technique. The research samples were 17 company financial statements that met the criteria as a sample of the company. The datacollection was performed by documentation techniques and the research data were analyzed by using multiple linear analysis. Hypothesis testing shows that the Individual Payout Ratio (DPR) and Liquidity (CR) do not have a significant effect on stock prices. Profitability (NPM) has a significant effect on Stock Prices. The value of Adjusted R Square was 0.275 indicating that variations in the DPR, CR, and NPM can explain variations in the variable Stock Price up to 27.5% while the remaining 72.7% can be explained by other factors outside the variables that have not been examined.
Pengaruh Struktur Modal, Net Profit Margin (NPM) dan Ukuran Perusahaan terhadap Kebijakan Dividen pada Perusahaan Sub Sektor Consumer Goods yang terdaftar di Bursa Efek Indonesia Periode 2011-2015
Authors: Lubis Mahmuddin Syah , - Yusneni Afrita Nasution , - Elim Suryenti
Published: February 2022

The objective of the research was to examine and analyze the influence of capital structure, net profit margin and company size on dividend policy in consumer goods sub-sector companies listed in the Indonesia Stock Exchange period 2011-2015. The research used descriptive research methode. The population was 40 companies in the consumer goods sub-sector listed in the Indonesia Stock Exchange for the period 2011 – 2015, and 17 of them were used as the samples, taken by using purposive sampling technique. The data were analyzed by using multiple linear regression using SPSS. The results of the research showed that the variables of Capital Structure, Net Profit Margin and Company Size simultaneously had influence on Dividend Policy. Partially, Capital Structure had insignificant influence on Dividend Policy, Net Profit Margin had positive and significant influence on Dividend Policy and Company Size had positive and significant influence on Dividend Policy.
Pengaruh Current Ratio, Debt To Equity Ratio, dan Inventory Turn Over terhadap Return On Asset pada Perusahaan Sektor Property dan Real Estate yang Terdaftar di BEI Tahun 2014-2018
Authors: Ramayana Endalit , - Abd. Wahid Rizki Sahputra , - Ivonia Florensia , - Siska Ika Sartika , - Januardin
Published: February 2022

This study aims to determine the effect of Current Ratio, Debt To Equity Ratio and Inventory Turn Over on Return On Asset This study was taken from property and real estate sector companies listed on the Indonesia Stock Exchange in 2014-2018. The population contained in the property and real estate sector is 48 companies. The samples studied are 27 companies selected using purposive sampling techniques so that the total sample to be used for 5 years becomes 135 samples. The analysis method used is multiple linear regression analysis with tools help SPSS 20. The results of the F test show that simultaneously the independent variables Current Ratio, Debt To Equity ratio and Inventory Turn Over influence and significantly affect Return On Asset The t test results indicate that partially, Current Ratio, Debt To Equity Ratio and Inventory Turn Over have significant and significant influence on Return On Asset.
Pengaruh Kualitas Produk dan Promosi terhadap Keputusan Pembelian Golden Farm French Fries pada PT. Sukanda Djaya Medan
Authors: Sitompul Melva Melany
Published: February 2022

Marketing activities in the company are the main thing in keeping the company able to provide products in accordance with customer expectations. The company’s ability to provide products that meet customers expectations will certainly be a value for customers in giving trust to the company and continuously buying these products.This of course will also make the income owned by the company able to increase.Purchasing decisions are decisions that are given determining which product to choose and to buy.Purchasing decisions are important when the company is able to maintain customer confidence properly, it will create repeat purchases from consumers which of course will make profits for the company.Product quality is a product’s ability to meet consumer expactations. High product quality will give a good impression to consumers when consuming these products. All consumers expect good quality when buying a product. Product quality factors are closely related to consumer choice. Promotion is an activity to introduce the features of product to cunsumers.Promotion is very important in managing and supporting companies in selling the products they have. With the promotion the company will be better able to introduce products to consumers in the company.
Pengaruh Komunikasi dan Disiplin Kerja terhadap Kinerja Karyawan pada PT. Mitra Butterindojaya
Authors: - Nathania Mulkan , - Yeni Ariesa
Published: February 2022

The research was conducted at PT Mitra Butterindo Jaya as the object of the research. PT. Mitra Butterindo Jaya is a company engaged in the distribution of cake ingredients. For this study, researchers only took special research employees at the Medan head office in charge of the sales of PT. Mitra Butterindo Jaya. In interviews and preliminary research observations, there were problems with poor employee performance, such as the number of employees who did not complete their tasks on time, decreased employee accuracy in carrying out their duties and responsibilities within the company and difficulties in cooperation between employees. This also resulted in a decrease in sales experienced by the company. The problem with communication problems is the clarity of communication between employees that has not been going well, the communication that is carried out is often not correct in conveying language and the flow of communication that is carried out is still often an error. This results in frequent errors in carrying out work. The total population of 80 people and 30 people were taken from other companies for validity and reliability testing. Theories used to support research are human resource management theories related to discipline, work stress and compensation for performance. The research method used is a quantitative approach with quantitative descriptive research type. Methods of data collection by interview, distribution of questionnaires and documentation study. The analytical method used is multiple linear regression, coefficient of determination and simultaneous testing (F-test) (72,231> 3,12) with value and partially (t-test) (6,730> 1,991) and (2,163> 1,991). The results showed that communication and work discipline simultaneously and partially had a significant positive effect on employee performance with a determination coefficient of 64.3% which affected employee performance variables.
Jóvenes qom en el Gran Buenos Aires
Authors: Beiras del Carril Victoria
Published: February 2022

En este trabajo se observa el uso, la difusión y los sentidos construidos sobre la lengua qom y la palabra escrita a través de los espacios virtuales de una banda de “rap originario” de jóvenes qom del Gran Buenos Aires. Nos interesa analizar de qué modo se pone en juego su repertorio lingüístico y cómo este uso colabora con la visibilización de la lengua indígena y desafía la preeminencia de lo monolingüe y el español. A su vez, al ser un discurso escenificado para audiencias mayores, exploramos de qué modo los jóvenes se apropian de las tendencias globales y las vinculan con las locales de maneras innovadoras.
Pueblos indígenas y la enseñanza de la historia en perspectiva intercultural en la escuela secundaria del sur bonaerense (Argentina)
Authors: Perrière Hernán
Published: February 2022

En este artículo abordo la enseñanza de la Historia en tres escuelas secundarias de la ciudad de Bahía Blanca desde una perspectiva etnográfica, con la intención de problematizar los supuestos nacionalizadores presentes en los discursos escolares tendientes a invisibilizar a los pueblos indígenas. Cuestionar estos discursos, permitió analizar cómo se reactualizan las visiones de nacionalidad que históricamente han justificado el genocidio indígena. Además, estudiar las tensiones entre la continuidad del mandato nacionalista dominante y la incorporación de la perspectiva intercultural según la Ley de Educación Nacional (2006). Para esto presento tres planos de análisis: el de la larga duración que marca una continuidad en el tratamiento de la nacionalidad desde mediados del siglo XIX. El de la continuidad relativa que incorpora el análisis de las normativas escolares destacando la menciones a la interculturalidad y por último el análisis de la enseñanza de la Historia en la cotidianeidad escolar.
¿Es posible conservar una Salamanca? Reflexiones sobre arqueología, conservación y usos locales del patrimonio desde una cueva con arte rupestre de Catamarca
Authors: Gheco Lucas , Oviedo Melisa Rodriguez , Gastaldi Marcos , Quesada Marcos
Published: February 2022

Este trabajo se concentra en una cueva con arte rupestre ubicada en la provincia de Catamarca del noroeste argentino. Pero dicho abrigo rocoso es mucho más que un sitio arqueológico; también es una potente salamanca, evento/lugar de adquisición de dones extraordinarios mediante pactos diabólicos. Frente a este caso de estudio paradigmático, nos preguntamos: ¿es posible conservar una salamanca? A partir de dicho interrogante y de nuestra particular experiencia al visitar la cueva, este trabajo tiene como objetivo discutir y reflexionar sobre los alcances, tensiones y disputas en torno a las nociones de patrimonio y conservación, pero también sobre las afectaciones en el trabajo de campo. ¿Cómo deberíamos actuar, en tanto arqueologxs, frente a las implicancias legales de proteger el “sitio arqueológico”? ¿Es posible conciliar dichas acciones de conservación/restauración con los usos actuales de la cueva? ¿En qué medida el abrigo es solo un “sitio arqueológico”? Enredadxs en estas preguntas, a lo largo de este ensayo presentamos algunos puntos problemáticos en donde se anudan la conservación, la arqueología y los usos locales del patrimonio.
“Vamos abriendo caminos…”Experiencias de formación en educación intercultural en la provincia de Neuquén
Authors: Trpin Verónica , Gonzalez Mariana
Published: February 2022

La interculturalidad surge vinculada al campo educativo y a los procesos de escolarización de niños/as pertenecientes a Pueblos Originarios. Sin embargo, particularmente en la Argentina, lejos de agotarse en la escolarización de grupos étnicos, el campo de la educación interculturalse ha configurado como un espacio de disputa, de reflexión teórica y política y de generación de prácticas pedagógicas que ponen en cuestión la naturaleza homogeneizadora de los sistemas educativos tradicionales. Es así como la educación intercultural necesita ser pensada como un conjunto de estrategias pedagógicas situadas y atravesadas por procesos culturales, económicos, políticos y sociales y que involucran múltiples actores/as comprometidos/as. En este artículo, nos focalizaremos en el recorrido de experiencias en formación en interculturalidad coordinadas desde la articulación de organismos nacionales y organizaciones sociales en la provincia de Neuquén, las cuales expresan debates en torno a cómo posicionarnos sobre la educación intercultural y sus alcances en los territorios.
Trayectorias escolares y estrategias de permanencia entre jóvenes indígenas universitarios (Salta, Argentina)
Authors: Rodríguez Nuria Macarena , Ossola María Macarena
Published: February 2022

En este artículo se presenta un análisis de las dinámicas de inclusión-exclusión presentes en las trayectorias educativas de los jóvenes indígenas que conforman la Comunidad de Estudiantes Universitarios de Pueblos Originarios, en la Universidad Nacional de Salta. El interés está puesto en explicar de qué forma las experiencias previas, en la educación formal, permean y condicionan las estrategias de retención y permanencia que se desarrollan en la Universidad. En el desarrollo de trabajo se reconocen las experiencias y huellas que los estudiantes universitarios traen consigo de sus años de escolarización, no sólo en lo que refiere a contenidos escolares, sino también en lo que concierne a la construcción de expectativas.
Light-Emitting Diodes Based on Two-Dimensional Nanoplatelets
Authors: Guo Yating , Gao Feng , Huang Pan , Wu Rong , Gu Wanying , Wei Jing , Liu Fangze , Li Hongbo
Published: February 2022

Colloidal semiconductor nanocrystals (NCs) attract significant interest in recent years due to their narrow and tunable emission wavelength in the visible range, as well as high photoluminescence quantum yield (PLQY), which are highly desired in display technologies. The high-quality NCs have been recognized as vital luminescent materials in realizing next-generation display devices. With further development, NCs with near-unity PLQY have been successfully synthesized through engineering of the core/shell heterostructure. However, as the external quantum efficiency (EQE) of the nanocrystal light-emitting diodes (LEDs) approaches the theoretical limit of about 20%, the low out-coupling factor proposes a challenge of enhancing the performance of a device when using the spherical QDs. Hence, the anisotropic NCs like nanoplatelets (NPLs) are proposed as promising solutions to improve the performance of nanocrystal LEDs. In this review, we will summarize the synthetic strategies of two-dimensional (2D) NPLs at first. Then, we will introduce fundamental concepts of LEDs, the main approaches to realize LEDs based on nanoplatelets, and the recent progress. Finally, the challenges and opportunities of LEDs based on anisotropic NCs are also presented.
Методика розрахункової оцінки гідродинамічної повздовжньої сили на корпусах перспективних швидкісних засобів при русі по водній поверхні різного стану
Authors: Расстригін Олександр Олексійович , Зірка Андрій Леонідович , Бєляєв Данило Миколайович
Published: February 2022

У статті розглядаються методичні аспекти побудови вдосконаленої методики щодо оцінки гідродинамічної повздовжньої сили при розрахунках гідродинамічних характеристик швидкісних засобів, що рухаються по водній поверхні (безпілотні літальні апарати, безекіпажні надводні засоби, швидкісні судна, гідроплани, екраноплани, глісируючі засоби ураження, тощо), а також можливості обґрунтування та формування тактико-технічних вимог до них й прийняття проектних рішень на етапі їх концептуального проектування
Formalization of the Problem of Optimization of Base Places and Routes of the UAV Group
Authors: Hulianytskyi Leonid , Rybalchenko Oleg
Published: February 2022

Introduction. The problem of planning the mission of a set of heterogeneous unmanned aerial vehicles (UAVs)is considered, which is to survey and/or service a given set of targets in the field. A mathematical model of the problem and algorithms for its solving that is based on deterministic local search, as well as optimization by ant colonies are proposed. The efficiency of algorithms is investigated based on the results of solving problems with real objects in the field. The relative error of the results of each algorithm was obtained, which allowed to compare their efficiency.
The purpose of the paper is to solve a routing problem in different ways to reduce overall mission cost and compare the efficiency. The problem statement considers multiple starting points and destinations (depots) for UAVs with determined capacity, so algorithms proposed in the paper are designed to optimize the initial placement. Each UAV has a maximum flight distance because of an energy limit, though vehicles can be recharged by visiting one of previously placed depots. The mission goal is to visit all the given targets while minimizing the overall cost, so fuel consumption over distance, depot placement, and resources needed to survey and/or service of the target by each UAV are considered as components of the final cost metric to be minimized considering a set of specific constraints.
Results. To solve the given UAV routing problem, a max-min algorithm of ant systems was developed, which features step-by-step interaction of ants to form solutions, a hybrid taboo search algorithm and a deterministic local search algorithm - the decay vector method. The developed algorithms were tested both on the known travelling salesman problems, and on specially developed problems with multiple depots and additional restrictions.
Conclusions. The proposed algorithms which are based on ant colony optimization are compared both in terms of accuracy and computation time. A hybrid algorithm achieved slightly better score, though computation time has increased. Keywords: routing, combinatorial optimization, UAV, local search, ant colony optimization algorithms.
Biographies of the Kuravars in Tamil Novels
Authors: N Rathnakumar
Published: February 2022

Although realist novels in Tamil are largely colossal (Panjum Pasiyum, Malarum Sarugum, Thaagam) there is very little room for the minority race and are included in some parts of the novel. After the year of Two thousand, translation novels (Marathi) about tribes such as Lakshman Keikwat's Uchalia, Lakshman Mane's Upara, and Chandabai Kale's Kulathi changed the course of Tamil novels. The unbridled ethnographic biographies presented by these novels set the stage for other marginalized ethnic groups to come out of fiction, as well as the expansive boundaries of the Dalit novels. It is to be welcomed that the trend of writing novels focusing on the biographies of the Tamil ‘Kuravargal’ has developed in the Tamil context. Their cultural movements, such as the beliefs, rituals, diets, cults, habitat, and occupational crises of ethnic minorities, have begun to feature in recent narratives. In particular, Pandiyakkannan's novels Salavan, Malaipparai and Nugathadi can be read as doco- fictions. This article summarizes the center, format, and commentary of the novels.
Microscopic Eclipses Novel from an Anthropological Point of view
Authors: S Arputharani
Published: February 2022

Anthropology is the scientific fact about the origin, development, etc. of the human race. The human race has evolved spontaneously for thousands of years. There are unique historical messages for different types of social and ethnic peoples in the world. There are many differences in their marriage, birth, death, worship, rituals, occupations, and ceremonies. Okkalikars are significant among the various ethnic groups in Tamil Nadu. The cow is worshiped as a deity. These clans are seen as a tradition of worshiping the house deity and the clan deity. They worship the deity once in 12 years. Mothers are prominent in all wedding ceremonies. Urumi will kneel for any ritual. They are not in the habit of cutting down trees and sitting on a mat made of reed grass. This article explains the anthropological perspective of the Okkalikars people who migrated from Karnataka in the novel Nunveli kiraganangal under the headings of science, Microspheres of Humans, Synopsis, Okkalikars Name, History, Lifestyles, Customs and Rituals.
Application of Security System Legal Documents Reviewer Letters Using Blockchain Technology
Authors: Amelia Sindy , Widya Ningrum Oktaviana
Published: February 2022

the popularity of blockchain technology has been widely used in aspects of life in various fields and industries. Because previously blockchain technology was used as crypto or known as digital currency which has developed towards technology and digital is growing rapidly. Where the use of blockchain technology is a new innovation that is increasingly developing in data security systems to suit the times and become one of the modern technologies in the world of education. However, nowadays there are often crimes in the illegal falsification of reviewer letters that can be carried out by irresponsible people for personal interests and can harm the parties concerned. For that we need a data security technology without the need for a third party called blockchain that can maintain the authenticity of the reviewer's letter from the criminal actions of irresponsible parties in forging intentionally or unintentionally. Raharja College has applied blockchain technology to a tool called ABC (data security) and has been implemented on the adimas website which has been going on for two years. Blockchain technology has an encryption hash code or a unique code that is a sign that a letter that has been verified with the blockchain can be seen as different from the original or fake. Because blockchain technology has a level of data security with a block system that is interconnected and has an encryption hash code. This paper uses the literature study method by looking at previous papers with the same theme. This research has the aim that future researchers can produce new innovations in improving data security and improving the quality of technology that can produce new findings in more modern data security systems.
Comparative Analysis of Cryopreservation Methods for Expanded Ex Vivo Natural Killer Cells: Recommendations for Optimizing Research Technologies
Authors: Ласюков Е.А. , Вашкевич Е.П. , Мухаметшина А.С. , Новикова М.А. , Липай Н.В. , Шман Т.В.
Published: February 2022

Цель. На основании сравнительного анализа известных технологий криоконсервации экспансированных ex vivo естественных киллерных клеток рекомендовать к использованию наиболее эффективные в отношении сохранения жизнеспособности ЕК-клеток. Материалы и методы. В исследование было включено 10 образцов экспансированных ex vivo ЕК-клеток человека, замороженных в 4 типах криопротекторных смесей с использованием различных технологий заморозки и хранившихся в течение 30 суток в парах жидкого азота. Сохранность образцов после размораживания оценивали по показателям жизнеспособности, цитотоксической активности (ЦТА) и фенотипическому профилю клеток. Результаты. Среди исследованных нами криопротекторных смесей наилучшие показатели сохранения жизнеспособности и цитотоксической активности экспансированных ex vivo ЕК-клеток после криохранения были получены для двух вариантов смесей, в одной из которых ключевыми компонентами явились эмбриональная телячья сыворотка (ЭТС) (25%) и диметилсульфоксид (ДМСО) (10%), а во второй - декстран и ДМСО (5%). Заключение. Среди исследованных криопротекторных смесей наилучшие показатели сохранения жизнеспособности и цитотоксической активности экспансированных ex vivo ЕК-клеток после криохранения были получены для двух вариантов смесей: ключевыми компонентами одной из них являются ЭТС (25%) и ДМСО (10%); компонентами другой - декстран и ДМСО (5%).

Purpose. On the basis of a comparative analysis of known cryopreservation technologies for expanded ex vivo natural killer cells, to recommend for use the most effective NK cells in terms of preserving the viability. Materials and methods. The study included 10 samples of expanded ex vivo human EK cells, frozen in 4 types of cryoprotective mixtures using various freezing techniques and stored for 30 days in liquid nitrogen vapor. The safety of the samples after thawing was assessed in terms of viability, cytotoxic activity, and phenotypic cell profile. Results. Among the cryoprotective mixtures studied by us, the best results of preserving the viability and cytotoxic activity of expanded ex vivo NK cells after cryostorage were obtained for two variants of mixtures: the key components of the first mixture are FBS (25%) and DMSO (10%); the second components are dextran and DMSO (5%). Conclusion. Among the studied cryoprotectant, the best results of viability and cytotoxic activity of expanded ex vivo EK cells after cryostorage were obtained for two variants of agents: the key components of one of them are ETS (25%) and DMSO (10%); the other components are dextran and DMSO (5%).
Immunosuppressive Potential of Placenta-Derived Mesenchymal Stem Cells
Authors: Лях Е.Г. , Исайкина Я.И. , Шитикова М.Г. , Новикова М.А. , Савич Ю.В. , Жерносеченко А.А.
Published: February 2022

Введение. Мезенхимальные стволовые клетки (МСК) модулируют иммунный ответ путем взаимодействия с широким спектром иммунных клеток. Одним из источников МСК является послеродовая плацента, преимуществом использования которой является доступность исходного материала. Цель. Исследование иммунных взаимодействий между Т-лимфоцитами и МСК, полученными из различных тканей плаценты в смешанной культуре. Материалы и методы. С помощью проточной цитофлуориметрии устанавливали количество Т-лимфоцитов (CD3+) и их основных субпопуляций: Т-хелперов с иммунофенотипом CD3+CD4+ и цитотоксических Т-лимфоцитов (CD3+CD8+) на ранней и поздней стадиях активации по экспрессии CD38 и HLA-DR соответственно. Результаты. Иммуносупрессивная активность МСК, полученных из амниотической оболочки, хориона и децидуальной ткани плаценты, не различалась, и все МСК достоверно снижали пролиферацию активированных CD3+ лимфоцитов, Т-хелперов и цитотоксических Т-лимфоцитов (p<0,05) как на стадии ранней активации, так и на стадии поздней. Установлено, что плацентарные МСК и МСК костного мозга сопоставимо редуцируют количество CD3+ лимфоцитов. Заключение. МСК плаценты могут служить перспективным материалом для клеточной иммунотерапии.

Introduction. Mesenchymal stem cells (MSCs) modulate the immune response by interacting with a wide range of immune cells. A full-term placenta is one of the source MSCs with the easily accessible features. Purpose. To study the immune interactions between T lymphocytes and MSCs obtained from various tissues of the placenta in a mixed culture. Materials and methods. Using flow cytometry, the number of cells in the subpopulations of T lymphocytes CD3+, CD3+CD4+, CD3+CD8+at the early (CD38+) and late (HLA-DR+) stages of activation was determined. Results. The results showed that the immunosuppressive activity of MSCs obtained from the amniotic membrane, chorion, and decidual tissue of the placenta did not differ, and all MSCs significantly reduced the proliferation of activated CD3+ lymphocytes, T helper cells and cytotoxic T lymphocytes (p<0.05), at the early and late stage of activation. It was found that placental MSCs and bone marrow MSCs reduced the number of CD3+ lymphocytes in a comparable manner. Conclusion. Placental MSCs could serve as a promising material for cell based immunotherapy.
Graft-Versus-Host Disease after Prophylactic Donor Lymphocytes Infusion in Children with Acute Leukemia and JMML
Authors: Цветкова Л.А. , Паина О.В. , Кожокарь П.В. , Фролова А.С. , Рахманова Ж.З. , Екушов К.А. , Субора Н.В. , Шевелева П.В. , Доценко А.А. , Семенова Е.В. , Кулагин А.Д. , Зубаровская Л.С.
Published: February 2022

Профилактические инфузии донорских лимфоцитов используют у пациентов с высоким риском развития рецидива заболевания после алло-ТГСК. Данные по безопасности раннего введения ИДЛ у детей крайне ограничены. В работе отражены частота клинически значимой реакции «трансплантат против хозяина» (РТПХ) и ее связь с общей и безрецидивной выживаемостью. Проанализированы 37 детей с острыми лейкозами и ЮММЛ, получивших профилактические ИДЛ в течение первых 6 месяцев после алло-ТГСК. Развитие острой/хронической РТПХ средней степени выявлено у 7 из 37 детей (19%), не отмечено тяжелых форм РТПХ. Наиболее часто диагностировали кожную форму хронической РТПХ в сочетании с поражением печени. Случаи летальности, связанные с осложнениями после ИДЛ, не были зарегистрированы. Напротив, индукция острой/хронической РТПХ улучшала показатели безрецидивной выживаемости и не влияла на общую выживаемость, p=0,04 и p=0,3 соответственно.

Prophylactic donor lymphocytes infusion (DLI) is used in patients with a high risk of relapse after allo-HSCT. The data about safety of early start DLI in children are extremely limited. This study demonstrates the incidence of clinically significant graft versus host disease (GVHD) and correlation with overall and disease-free survival. We analyzed 37 children with acute leukemia and JMML, who had received prophylactic DLI within the first 6 months after HSCT. Moderate acute/chronic GVHD was diagnosed in 7/37 children (19%), nobody developed severe GVHD. The most children had chronic GVHD with involvement of skin and liver. There were no cases GVHD-related mortality. The induction of acute/chronic GVHD improved the relapse-free survival and did not influence on overall survival, p=0.04 and p=0.3, respectively.
Treatment of Large Plasmacytoma in Patients with Multiple Myeloma (Clinical Case)
Authors: Терентьева М.А. , Искров И.А. , Козак О.Н. , Траханов Д.Э.
Published: February 2022

Множественная миелома на сегодняшний день из разряда неизлечимых заболеваний перешла в разряд хронических. Улучшение общей выживаемости связано с включением в лечение высокодозной химиотерапии с последующей аутологичной трансплантацией гемопоэтических стволовых клеток, а также с использованием в лечении новых классов препаратов. Обычно у пациентов с множественной миеломой пролиферация клональных плазматических клеток ограничена костным мозгом. Однако у части пациентов также развивается экстрамедуллярная миелома, характеризующаяся присутствием клональных плазматических клеток за пределами костного мозга. С точки зрения клинического исхода наличие экстрамедуллярной плазмоцитомы на момент постановки диагноза ассоциировано с неблагоприятным прогнозом. Рецидив заболевания в виде экстрамедуллярной плазмоцитомы характеризуется более агрессивным течением с длительностью общей выживаемости менее 6 месяцев. В качестве методов лечения используют лучевую терапию, хирургическое лечение, системную химиотерапию, однако результаты лечения пациентов с экстрамедуллярной плазмоцитомой остаются неудовлетворительными, и необходимы новаторские стратегии.

Сurrently the multiple myeloma has moved from the category of incurable diseases to the category of chronic ones. The improvement in overall survival is associated with the inclusion of high-dose chemotherapy in treatment, followed by autologous hematopoietic stem cell transplantation, as well as new classes of drugs in the treatment. Typically, in patients with multiple myeloma, clonal plasma cell proliferation is limited to the bone marrow. However, some patients also develop extramedullary myeloma, characterized by the presence of clonal plasma cells outside the bone marrow. As regards clinical outcome, the presence of extramedullary plasmacytoma at the time of diagnosis is associated with a poor prognosis. Relapse of the disease in the form of extramedullary plasmacytoma is characterized by a more aggressive course with an overall survival of less than 6 months. Radiation therapy, surgical treatment, and systemic chemotherapy are used as treatment options, but the results of ones in patients with extramedullary plasmacytoma remain unsatisfactory, and innovative strategies are required.
Mechanistic determination of tear film thinning via fitting simplified models to tear breakup
Authors: Luke Rayanne , Braun Richard , Begley Carolyn
Published: February 2022

Purpose: Little quantitative or mechanistic information about tear film breakup can be determined directly via current imaging techniques. In this paper, we present simplified mathematical models based on two proposed mechanisms of tear film breakup: evaporation of water from the tear film and tangential fluid flow within the tear film. We use our models to determine whether one or a combination of the two mechanisms causes tear film breakup in a variety of instances. In this study, we estimate related breakup parameters that cannot currently be measured in breakup during subject trials, such as tear film osmolarity and thinning rates. The present study validates our procedure against previous work.Methods: Five ordinary differential equation models for tear film thinning were designed that model evaporation, osmosis, and various types of tangential flow. Eight tear film breakup instances occurring within a time interval of 1–8 s postblink of five healthy subjects thatwere identified in fluorescence images in previous work were fit with these five models. The fitting procedure used a nonlinear least squares optimization that minimized the difference of the computed theoretical fluorescent intensity from the models and the experimental fluorescent intensity from the images. The optimization was conducted over the evaporation rate and up to three tangential flow rate parameters. The smallest norm of the difference was determined to correspond to the model that best explained the tear film dynamics.Results: All of the breakup instances were best fit by models with time-dependent tangential flow. Our optimal parameter values and thinning rate as well as tangential fluid flow profiles compare well with previous partial differential equation model results in most instances.Conclusion: Our fitting results suggest that a combination of tangential fluid flow and evaporation cause most of the breakup instances. Comparison with results from previous work suggests that the simplified models can capture the essential tear film dynamics in most cases, thereby validating this procedure for wider usage.
Gambaran Kejadian Kehamilan Ektopik Terganggu
Authors: Aravianti Ni Luh Sri , Darmapatni Made Widhi Gunapria , Somoyani Ni Ketut
Published: February 2022

Ectopic pregnancies occur in 19,7 cases out of 1000 pregnancies, and is the leading cause of maternal death in the first trimester.  Risk factors for disrupted ectopic pregnancy include age, gravidity, medical history, past obstetric history, and history of contraception. The purpose of this study was to describe the incidence of disrupted ectopic pregnancy at the Wangaya Regional General Hospital, Denpasar City. This type of study was descriptive with a cross sectional approach. The results of this study are the incidence of disrupted ectopic pregnancy occurred at an average age of 27.65 years, and the most at the age of 20-35 years, multigravida, without a history of sexually transmitted infections and pelvic inflammatory disease, without a history of disrupted ectopic pregnancy, abortion, caesarean section, and tubal surgery, and no history of contraception. The study suggest that pregnant women of productive age and multigravida to carry out more routine antenatal care and carry out ultrasound at least once in early pregnancy. In future study, it is recommended to use primary data.

 

Keywords: Disrupted ectopic pregnancy, Age, Gravidity, Medical history, Past Obstetrics History.
Faktor-Faktor yang Mempengaruhi Nyeri Punggung Ibu Hamil Trimester III: Literatur Review
Authors: Arummega Melati Nur , Rahmawati Alfiah , Meiranny Arum
Published: February 2022

Back pain is caused by pain in the lumbosacral area.  The increase in intensity with increasing gestational age results from a shift in the center of gravity and changes in body posture.  Back pain from sacroiliac/lumbar can be a long term back pain if not treated promptly.  Literature review aims to examine more deeply about back pain in pregnant women in the third trimester, there were factors that influence it by reviewing.  Methods literature review by searching on Google Scholar and PubMed.  The keyword criteria are "pregnancy", "back pain", "low back pain pregnancy factors", "back pain pregnant women activities".  After the study was conducted, national articles 9 and 15 were obtained. Factors that affect back pain in third trimester pregnant women can be classified from gestational age, age, parity, daily activities that affect back pain and body relaxation can reduce back pain  .

 

Keywords: Daily Activities, 3rd Trimester Of Pregnancy, Back Pain
Faktor Risiko Terjadinya Persalinan Prematur
Authors: Panada Sedianing Drastita  , Hardianto Gatut , Fitriana Farida , Utomo Martono Tri
Published: February 2022

Preterm labor is an early delivery that occurs at gestational age after 20 weeks and before 37 weeks. In 2016, Indonesia was ranked 7th with the highest number of toddler deaths caused by compilations of premature birth. This study aims to analyze the relationship of risk factors dor preterm labor at RSU Dr. Wahidin Sudiro Husodo Mojokerto. The study was held from January until June in 2021. Research Method used analytic observasional with case control design. The instruments used is medical records. Analyse data used bivariate with Chi Square. The result age p = 0,005);anemia (p=0,018); PPROM (p =0,009); and previous preterm labor (p=0,49). The conclusions that age, anemia, and PPROM there are significant relationship with preterm labor statiscally. In this study there was no relationship between previous preterm labor with occurance of preterm labor in next pregnancies.

 

Keyword: Preterm Labor, Age, Anemia, PPROM, Previous Preterm Labor
Isparta’da Üretilen Hazır Betonların İstatistiksel Analizi
Authors: TOPÇU İlker Bekir , TUNA Abdullah
Published: February 2022

Isparta bir üniversite şehri olduğu için son yıllarda hızlı bir nüfus artışı dikkat çekmektedir. Bu nüfus artışına bağlı olarak bölgedeki yapılaşma da artmaktadır. Bununla birlikte Isparta ili deprem riski haritasında genel olarak birinci derece deprem kuşağı üzerinde yer alması sonucu kentsel dönüşüm çalışmalarının günümüz ihtiyaç ve beklentilerini karşılaması gerekmektedir. Bu nedenle yapılarda kullanılan betonun kalitesi önem kazanmıştır. Çalışmada Isparta’da 2019-2020 yıllarında farklı beton santrallerinde üretilip, farklı şantiyelere dökülen hazır betonlardan alınan numunelerden C30/37 sınıfı betonların basınç dayanım deney sonuçlarının istatistiksel analizi yapılmıştır. 15x15x15 cm boyutlarında toplam 681 adet numuneye ait dayanım sonuçlarından yararlanılarak, Isparta’da C30/37 sınıfına göre beton kalitesinin ne seviyede olduğu belirlenmeye çalışılmıştır. Sonuç olarak Isparta ilinde dayanım deneyleri yapılan C30/37 sınıfı hazır beton numunelerinde standartların büyük ölçüde sağlandığı görülmüştür. Ayrıca bir üst beton sınıfına sarkmaların fazla olması nedeniyle 2019-2020 yıllarında Isparta ilinde standartlara uygun ve aynı zamanda ekonomik olmayan beton üretildiği sonucuna varılmıştır.