bluuebunny/crossref_metadata_2025 huggingface dataset:
INFLUENCE OF HEPATOCELLULAR CARCINOMA ETIOLOGY IN THE SURVIVAL AFTER RESECTION
Authors: LOPES Felipe de Lucena Moreira , COELHO Fabricio Ferreira , KRUGER Jaime Arthur Pirolla , FONSECA Gilton Marques , ARAUJO Raphael Leonardo Cunha de , JEISMANN Vagner Birk , HERMAN Paulo
Published: July 2016

ABSTRACT Background: Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer and its incidence is increasing around the world in the last decades, making it the third cause of death by cancer in the world. Hepatic resection is one of the most effective treatments for HCC with five-year survival rates from 50-70%, especially for patients with a single nodule and preserved liver function. Some studies have shown a worse prognosis for HCC patients whose etiology is viral. That brings us to the question about the existence of a difference between the various causes of HCC and its prognosis. Aim: To compare the prognosis (overall and disease-free survival at five years) of patients undergoing hepatectomy for the treatment of HCC with respect to various causes of liver disease. Method: Was performed a review of medical records of patients undergoing hepatectomy between 2000 and 2014 for the treatment of HCC. They were divided into groups according to the cause of liver disease, followed by overall and disease-free survival analysis for comparison. Results: There was no statistically significant difference in the outcomes of the groups of patients divided according to the etiology of HCC. Overall and disease-free survival at five years of the patients in this sample were 49.9% and 40.7%, respectively. Conclusion: From the data of this sample, was verified that there was no prognostic differences among the groups of HCC patients of the various etiologies.
COST-EFFECTIVENESS OF PERIOPERATIVE IMMUNONUTRITION IN GASTROINTESTINAL ONCOLOGIC SURGERY: A SYSTEMATIC REVIEW
Authors: REIS Audrey Machado dos , KABKE Geórgia Brum , FRUCHTENICHT Ana Valéria Gonçalves , BARREIRO Taiane Dias , MOREIRA Luis Fernando
Published: July 2016

ABSTRACT Introduction: Costs, length of hospital staying and morbidity are frequently and significantly increased as a result of infections and other complications following surgical procedure for gastrointestinal tract cancer. Recently, improving host defence mechanisms have become a target of interest. Immunonutrition aims at improving immunity, most likely providing key nutrients to maintain T-lymphocyte and other host defence. Aim : To evaluate the immunonutrition in cancer patients who are operated by digestive diseases and assess the cost-effectiveness of this supplementation. Methods: This study consisted of a systematic review of the literature based on reference analyses retrieved from current databases such as PubMed, Lilacs and SciELO. The search strategy was defined by terms related to immunonutrition [immunonutrition, arginine, omega-3 and nucleotides] in combination with [costs, cost-effective and cost-effectiveness] as well as [gastrointestinal cancer surgery, oesophageal, gastric or pancreatic surgery] in English, Portuguese or Spanish language. For cost analyses, currencies used in the manuscripts were all converted to American dollars (US$) in order to uniform and facilitate comparison. Six prospective randomized studies were included in this review. Conclusion: The cost-effectiveness was positive in most of studies, demonstrating that this diet can significantly reduce hospital costs in the North hemisphere. However, similar studies needed to be carried to determine such results among us.
ESTABILIDADE E ADAPTABILIDADE EM TESTES DE PROGÊNIES DE MYRACRODRUON URUNDEUVA SOB QUATRO SISTEMAS DE PLANTIO
Authors: Canuto Daniela Silvia de Oliveira , Silva Alexander Marques da , Moraes Mario Luiz Teixeira de , Resende Marcos Deon Vilela de
Published: July 2016

RESUMO A espécie Myracrodruon urundeuva, ou aroeira, possui madeira resistente, porém de crescimento lento, sendo recomendável o seu plantio consorciado com outras espécies como uma alternativa de renda até seu completo crescimento e desenvolvimento. Assim este trabalho teve como objetivo avaliar a estabilidade e adaptabilidade em quatro testes de progênies de Myracrodruon urundeuva sob diferentes formas de plantio: consórcio com essências arbóreas (TP-1), homogêneo (TP-2), SAF com culturas anuais (TP-3) e SAF com eucalipto (TP-4), instalados em 1997 na Fazenda de Pesquisa, Extensão e Ensino da UNESP, campus Ilha Solteira - SP no município de Selvíria - MT, cujas sementes foram coletadas de 30 árvores matrizes localizada na Estação Ecológica de Paulo de Faria - SP. Foram avaliados a altura total (m), o diâmetro à altura do peito - DAP (cm) e a forma do fuste, aos dez anos idade. Foi utilizado o delineamento experimental de blocos casualizados. Para as estimativas de componentes de variância, parâmetros genéticos e estabilidade e adaptabilidade (MHPRVG) foi utilizado o software SELEGEN. A aroeira teve melhor desempenho quanto a altura no TP-3, DAP no TP-2 e a forma do fuste foi semelhante nos quatro TP. Os parâmetros genéticos indicaram que o DAP apresentou o maior controle e variação genética e correlação genótipos e ambientes. A seleção simultânea apresentou as melhores progênies idênticas a seleção do MHPRVG, o que indica ser este, um método mais refinado de seleção.
UTILIZAÇÃO DA TÉCNICA SUNSET LASER PARA DISTINGUIR SUPERFÍCIES USINADAS DE MADEIRA COM QUALIDADES SIMILARES
Authors: Andrade Anna Carolina de Almeida , Silva José Reinaldo Moreira da , Braga Junior Roberto Alves , Moulin Jordão Cabral
Published: July 2016

RESUMO A norma ASTM D 1666-11 (AMERICAN SOCIETY FOR TESTING AND MATERIALS - ASTM, 2011) classifica a qualidade da superfície de peças de madeira, após o seu processamento mecânico, embora essa classificação seja difícil de ser realizada visualmente e o uso de algumas ferramentas, como o laser de estado sólido, pode facilitar tal classificação. Assim, o objetivo foi avaliar o uso da técnica sunset laser para qualificar superfícies processadas mecanicamente com qualidades visuais semelhantes. Utilizou-se a tora da base de uma árvore de Khaya ivorensis e outra de K. senegalensis, ambas com 11 anos. Foram confeccionados 22 corpos de prova de dimensões 600x140x30 mm (CxLxE) de cada espécie. Os corpos de prova foram aplainados com velocidades de 2400, 3600 e 4000 min-1 e as velocidades de avanço foram pré-determinadas em 6 e 15 m.min-1. Em seguida, os corpos de prova foram iluminados com a técnica sunset laser e fotografados na alta resolução, as imagens foram transferidas para o software Image J. Para avaliar a qualidade da superfície pela técnica sunset laser utilizou-se as áreas de defeitos na madeira que são classificadas como regular e ruim pela norma ASTM D 1666-11 (ASTM, 2011). Houve diferença de classificação dos defeitos da madeira entre os dois métodos utilizados, sendo que 31 corpos de prova classificados como regular pela análise visual, 8 deles foram classificados como ruim pelo método do laser. A utilização do laser de estado sólido na técnica sunset laser mostrou-se mais eficiente para avaliar pequenas diferenças de defeitos da madeira processada mecanicamente em comparação com a avaliação visual.
MICROMORFOMETRIA FOLIAR DE PALICOUREA RIGIDA KUNTH. (RUBIACEAE) EM AMBIENTE DE CERRADO E CAMPO RUPESTRE
Authors: Gavilanes Manuel Losada , Castro Evaristo Mauro de , Pires Marinês Ferreira , Pereira Fabricio José , Pereira Márcio Paulo
Published: July 2016

RESUMO Este trabalho teve como objetivo um estudo anatômico descritivo e quantitativo da estrutura foliar de Palicourea rigida Kunth. (Rubiaceae), espécie que ocorre em áreas de cerrado e campo rupestre. As observações anatômicas foram realizadas em folhas de material fresco ou fixado, tratadas segundo metodologias usuais em anatomia vegetal. Foram observadas as seguintes características: epidermes do pecíolo e da lâmina foliar uniestratificadas; presença de tricomas tectores, simples, unisseriados, próximos, ou sobre as nervuras; estômatos do tipo paracítico presentes somente na face abaxial da folha; mesofilo com parênquima paliçádico de uma só camada de células; parênquima esponjoso com sete a nove camadas celulares com formas irregulares e tamanhos variados; idioblastos cristalíferos, observados em todos os parênquimas do pecíolo e lâmina foliar; feixes vasculares, do tipo colateral; colênquima observado, subepidermicamente, no pecíolo e nervuras de maior porte, em ambas faces; o padrão geral de nervação da espécie é pinado, camptódromo, broquidódromo. As análises micromorfométricas revelaram diferenças significativas em todos os itens analisados, sendo as médias mais elevadas encontradas nas folhas das plantas crescendo no cerrado. Isto sugere que a influência de fatores ambientais pode ter modulado respostas morfológicas nas plantas, visto que o tipo e distribuição dos tecidos não sofreram alterações nos dois ambientes.
BIOMASSA E ATIVIDADE MICROBIANA SOB DIFERENTES COBERTURAS FLORESTAIS
Authors: Braga Rafael Malfitano , Sousa Fabrizio Furtado de , Venturin Nelson , Braga Francisco de Assis
Published: July 2016

RESUMO Neste estudo avaliou-se a fertilidade do solo, a biomassa e atividade microbiológica do solo sob coberturas florestais de Eucalyptus grandis, Eucalyptus pilularis, Eucalyptus cloeziana e Corymbia maculata; Pinus caribaea var. hondurensis, com 40 anos de idade, e um fragmento de Floresta Estacional Semidecidual, localizados no campus da Universidade Federal de Lavras. Em amostras de solo coletadas na camada de 0-5 cm foram determinados parâmetros de fertilidade, a respiração basal e o carbono de biomassa microbiana. Os resultados mostraram que as espécies E. grandis e E. cloeziana mantiveram teores de carbono de biomassa microbiana mais elevados dentre os ecossistemas avaliados e iguais àqueles observados sob a floresta nativa. Em contraste, o solo sob pinus apresentou os menores índices microbiológicos. Sob C. maculata e E. pilularis os teores foram intermediários para este parâmetro. A respiração basal de todos os ecossistemas foi igual. O nível de fertilidade foi extremanente baixo sob todos os tipos de cobertura vegetal avaliados.
ÁREAS DE CONSERVAÇÃO, POBREZA E DESIGUALDADE SOCIAL: AVALIAÇÃO UTILIZANDO INDICADORES SOCIOECONÔMICOS EM MINAS GERAIS, BRASIL
Authors: Sálvio Geraldo Majela Moraes , Fontes Marco Aurélio Leite , Silveira Junior Wanderley Jorge da , Silva Helder Antônio da
Published: July 2016

RESUMO Neste estudo objetivou-se avaliar as possíveis correlações entre os indicadores de desenvolvimento socioeconômico dos municípios do estado de Minas Gerais, Brasil, e a presença de unidades de conservação (UC), tanto de uso sustentável como de proteção integral. Os valores de Índice de Desenvolvimento Humano (IDH) e Índice de Gini (IG) foram comparados entre os municípios com e sem UC pelo teste não paramétrico Wilcoxon-Mann-Whitney. Testaram-se as correlações entre IDH e IG de cada município e suas áreas ocupadas por UC através do teste não paramétrico de correlação de Spearman. Identificaram-se 560 UC nos 853 municípios do estado. Os municípios com UC não apresentaram IDH significativamente diferentes dos demais, mas encontraram-se diferenças significativas nos valores de IG, superiores nos municípios com UC. Não se encontraram correlações significativas entre os IDH dos municípios e suas áreas ocupadas por UC. Mas encontraram-se correlações significativas entre IG e as áreas ocupadas por UC, associando as UC a maiores desigualdades socioeconômicas. Deve-se incorporar as populações aos esforços de conservação por meio de programas que as beneficiem, em especial o pagamento por serviços ambientais, entre outras estratégias conservacionistas.
MODELAGEM E PROGNOSE DO PREÇO DE CARVÃO USANDO UM SISTEMA NEURO-FUZZY
Authors: Araújo Júnior Carlos Alberto , Silva Liniker Fernandes da , Silva Marcio Lopes da , Leite Helio Garcia , Valdetaro Erlon Barbosa , Donato Danilo Barros , Castro Renato Vinícius Oliveira
Published: July 2016

RESUMO Utilizando dados da série temporal mensal de preços de carvão vegetal em Minas Gerais no período de janeiro de 2000 à setembro de 2014, este estudo teve como objetivo avaliar o uso do sistema neuro-fuzzy para modelagem e previsão de preços. Foram utilizados quatro estruturas de modelagem considerando diferentes defasagens da variável preço (1, 2, 3, 4 e 5 defasagens). A estrutura mais adequada para o sistema neuro-fuzzy foi escolhido com base nos valores de raiz quadrada do erro médio quadrático, erro médio absoluto, erro médio quadrático, erro médio percentual absoluto e máximo erro percentual absoluto para o período de previsão. Com os resultados encontrados, é possível concluir que um sistema neuro-fuzzy pode ser usado para prever corretamente os preços do carvão vegetal.
ADSORPTION OF NANOWOLLASTONITE ON CELLULOSE SURFACE: EFFECTS ON PHYSICAL AND MECHANICAL PROPERTIES OF MEDIUM-DENSITY FIBERBOARD (MDF)
Authors: Taghiyari Hamid Reza , Majidi Roya , Jahangiri Asghar
Published: July 2016

ABSTRACT Effects of nanowollastonite (NW) adsorption on cellulose surface were studied on physical and mechanical properties of medium-density fiberboard (MDF) panels; properties were then compared with those of MDF panels without NW-content. The size range of NW was 30-110 nm. The interaction between NW and cellulose was investigated using density functional theory (DFT). Physical and mechanical tests were carried out in accordance with the Iranian National Standard ISIRI 9044 PB Type P2 (compatible with ASTM D1037-99) specifications. Results of DFT simulations showed strong adsorption of NW on cellulose surface. Moreover, mechanical properties demonstrated significant improvement. The improvement was attributed to the strong adsorption of NW on cellulose surface predicted by DFT, adding to the strength and integrity between wood fibers in NW-MDF panels. It was concluded that NW would improve mechanical properties in MDF panels as a wood-composite material, as well as being effective in improving its biological and thermal conductivity.
A política do erotismo na maturidade feminina: um estudo sobre as relações entre os estados hipocondríacos e melancólicos
Authors: Gromann Regina Maria Guisard
Published: July 2016

Este artigo enfoca as relações entre estados hipocondríacos e melancólicos presentes na passagem da maturidade feminina, isto é, no período do climatério e da menopausa, atravessado pela perda radical da capacidade biológica da procriação. Salienta-se o pathos feminino nesta etapa e a necessidade da mulher estabelecer uma nova política erótica que surge do seu corpo em transição, por meio da reedição préedípica e edípica vivida a partir da regressão e da transferência no processo analítico.
Para pensar o afeto
Authors: Menezes Aluisio Pereira de
Published: July 2016

Apresentação de um conjunto de formulações relativas ao “afeto” anteriores ao surgimento da psicanálise. Dificuldade da psicanálise em construir uma concepção propriamente psicanalítica. Contribuição da fenomenologia de Husserl para o estudo do afeto. Atualidade das concepções do afeto marcadas pelas neurociências. As maneiras principais de ver o problema da conceituação do afeto no pensamento psicanalítico.
Esperança não é esperar, é caminhar. Reflexões filosóficas sobre a esperança e suas ressonâncias na teoria e clínica psicanalíticas
Authors: Rocha Zeferino
Published: July 2016

Depois de uma breve introdução na qual são definidos o objetivo e o roteiro do artigo, o autor comenta, na primeira parte, dois fragmentos de Heráclito de Éfeso, como ponto de partida para uma abordagem filosófica da esperança, e, em seguida, define seu papel e função na dinâmica da temporalidade humana. Na segunda parte, são discutidas as possíveis ressonâncias desta visão filosófica da esperança sobre a questão dos ideais, o trabalho do luto e da melancolia, bem como seu papel no tratamento analítico dos assim chamados “clientes sem esperança”.
A catástrofe de Kraepelin
Authors: Câmara Fernando Portela
Published: July 2016

A psiquiatria moderna nasce de uma descontinuidade histórica que a leva a uma mudança súbita radical, tendo Kraepelin como o agente dessa transformação. Os fatos analisados mostram que essa mudança manifestou-se como um típico salto qualitativo, sendo analisados sob o método interpretativo da Teoria da Catástrofe.
O banzo e outros males: o páthos dos negros escravos na Memória de Oliveira Mendes
Authors: Oda Ana Maria Galdini Raimundo
Published: July 2016

Este artigo analisa o estudo sobre o tráfico negreiro e as doenças dos escravos, escrito por Luis Antonio Oliveira Mendes, em 1793.
Air pollution and respiratory diseases: ecological time series
Authors: Nascimento Luiz Fernando Costa , Vieira Luciana Cristina Pompeo Ferreira , Mantovani Kátia Cristina Cota , Moreira Demerval Soares
Published: July 2016

ABSTRACT CONTEXT AND OBJECTIVE: Exposure to air pollutants is one of the factors responsible for hospitalizations due to respiratory diseases. The objective here was to estimate the effect of exposure to particulate matter (such as PM2.5) on hospitalizations due to certain respiratory diseases among residents in Volta Redonda (RJ). DESIGN AND SETTING: Ecological time series study using data from Volta Redonda (RJ). METHODS: Data on hospital admissions among residents of Volta Redonda (RJ), between January 1, 2012, and December 31, 2012, due to pneumonia, acute bronchitis, bronchiolitis and asthma, were analyzed. Daily data on PM2.5 concentrations were estimated through the CCATT-BRAMS model. The generalized additive Poisson regression model was used, taking the daily number of hospitalizations to be the dependent variable and the PM2.5 concentration to be the independent variable, with adjustment for temperature, relative humidity, seasonality and day of the week, and using lags of zero to seven days. Excess hospitalization and its cost were calculated in accordance with increases in PM2.5 concentration of 5 µg/m3. RESULTS: There were 752 hospitalizations in 2012; the average concentration of PM2.5 was 17.2 µg/m3; the effects of exposure were significant at lag 2 (RR = 1.017), lag 5 (RR = 1.022) and lag 7 (RR = 1,020). A decrease in PM2.5 concentration of 5 µg/m3 could reduce admissions by up to 76 cases, with a decrease in spending of R$ 84,000 a year. CONCLUSION: The findings from this study provide support for implementing public health policies in this municipality, which is an important steelmaking center.
Economic evaluation of the new oral anticoagulants for the prevention of thromboembolic events: a cost-minimization analysis
Authors: Marcolino Milena Soriano , Polanczyk Carisi Anne , Bovendorp Ana Carolina Caixeta , Marques Naiara Silveira , Silva Lilian Azevedo da , Turquia Cintia Proveti Barbosa , Ribeiro Antonio Luiz
Published: July 2016

ABSTRACT CONTEXT AND OBJECTIVE: Randomized clinical trials have shown that the new oral anticoagulants have at least similar impact regarding reduction of thromboembolic events, compared with warfarin, with similar or improved safety profiles. There is little data on real costs within clinical practice. Our aim here was to perform economic analysis on these strategies from the perspective of Brazilian society and the public healthcare system. DESIGN AND SETTING: Cost-minimization analysis; anticoagulation clinic of Hospital Municipal Odilon Behrens, Belo Horizonte, MG, Brazil. METHODS: Patients at the anticoagulation clinic were recruited between August and October 2011, with minimum follow-up of four weeks. Operational and non-operational costs were calculated and corrected to 2015. RESULTS: This study included 633 patients (59% women) of median age 62 years (interquartile range 49-73). The mean length of follow-up was 64 ± 28 days. The average cost per patient per month was $ 54.26 (US dollars). Direct costs accounted for 32.5% of the total cost. Of these, 69.5% were related to healthcare professionals. With regards to indirect costs, 52.4% were related to absence from work and 47.6% to transportation. Apixaban, dabigatran and rivaroxaban were being sold to Brazilian public institutions, on average, for $ 49.87, $ 51.40 and $ 52.16 per patient per month, respectively, which was lower than the costs relating to warfarin treatment. CONCLUSION: In the Brazilian context, from the perspective of society and the public healthcare system, the cumulative costs per patient using warfarin with follow-up in anticoagulation clinics is currently higher than the strategy of prescribing the new oral anticoagulants.
Splenic diffuse red-pulp small B-cell lymphoma associated with hepatitis B virus: a report of two cases
Authors: Kerbauy Mariana Nassif , Fernandes Carolina Melo , Bezerra Evandro Dantas , Lage Luis Alberto de Padua Covas , Siqueira Sheila Aparecida Coelho , Pereira Juliana
Published: July 2016

ABSTRACT CONTEXT: Splenic diffuse red-pulp small B-cell lymphoma is a rare disease, representing less than 1% of all non-Hodgkin lymphomas (NHL). This entity is characterized by involvement of bone marrow sinusoids and peripheral blood. The majority of cases are at an advanced stage when diagnosed. Its pathogenesis is still poorly understood. CASE REPORTS: We report on two patients with chronic non-replicating hepatitis B virus (HBV) who developed splenic diffuse red-pulp small B-cell lymphoma. Both of them were in stage IV at diagnosis and evolved with aggressive disease. Both of them achieved a complete response through chemotherapy, but one of them died due to infectious complications during bone marrow transplantation. The other decided not to undergo transplantation and continues not to show any evidence of disease today (three years after treatment). Some studies have shown a possible association between B-cell NHL and HBV. Nonetheless, the mechanism through which this oncogenic virus interacts with B-cell NHL is still poorly understood. HBV is lymphotropic and may insert into the host's genome, thus causing overexpression of oncogenes and downregulation of tumor suppressor genes. Therefore, chronic stimulation by HBV can increase B-cell proliferation, which promotes monoclonal expansion of these cells and results in malignancy. CONCLUSION: HBV may be implicated in the pathogenesis of this lymphoma, although no direct association between these two entities could be proved in the present study. Further investigations are necessary.
The domestic participation in birth assistance in the mid-twentieth century
Authors: Díaz Elena Andina , González José Siles
Published: July 2016

Abstract Objective: to describe how the progressive creation of the Social Security (providing widespread health care) affected the birth assistance in Spain from the 1940s to the 1970s in a rural area. Method: historical ethnography. Twenty-seven people who lived at that time were selected and interviewed guided by a semistructured script. Based on their testimonies, a chart was built with the functional elements involved in birth assistance in this region. Results: three agents performed such care: traditional midwives, women of the family/neighbors and health workers. Conclusion: although birth assistance had been transferred to the hands of the health workers from the forties in this region, women in labor continued to count on the domestic resources until the early seventies, when births were compulsorily transferred to hospitals. This research brings to light the names and recognizes the work performed by these female characters of the popular sphere, who helped women in labor of that community to give birth, for at least three decades.
Work ability and health of security guards at a public University: a cross-sectional study
Authors: Godinho Marluce Rodrigues , Ferreira Aldo Pacheco , Greco Rosangela Maria , Teixeira Liliane Reis , Teixeira Maria Teresa Bustamante
Published: July 2016

Abstract Objective: to evaluate the work ability and health status of security guards at a public University. Methods: a cross-sectional, descriptive, and analytical study was carried with 119 security guards. The following instruments were used: Work Ability Index (WAI), Patient Health Questionnaire (PHQ-9), International Physical Activity Questionnaire (IPAQ, short), Alcohol Use Disorders Identification Test (AUDIT), Medical Outcomes Study (MOS), and Demand-Control-Support (DCS). Descriptive statistics were used to describe the study samples and the Spearman's coefficient correlation was performed to assess the WAI. Significance level was set at 5%. Results: samples were composed by men; the mean age was 54.9 years (SD=5.7); 80% had partners, and 75% had basic education. The majority (95%) had only one job, the average length of service was 24.8 years (SD=11), ranging from 3 to 43 years. 88.9% worked ≤40 hours and 75% did not work at night shift or rotating shifts. The average score given to work ability was good (40.7 points), with significant correlation to social support at work (p-value=0.002), health conditions (p-value=0.094), and depression symptoms (p-value=0.054). Conclusion: this study showed that many characteristics might affect the work ability scores. Considering the results, we note that healthy life habits and a reorganization of work environments should be encouraged.
Labor stimulation with oxytocin: effects on obstetrical and neonatal outcomes
Authors: Hidalgo-Lopezosa Pedro , Hidalgo-Maestre María , Rodríguez-Borrego María Aurora
Published: July 2016

Abstract Objective: to evaluate the effects of labor stimulation with oxytocin on maternal and neonatal outcomes. Method: descriptive and analytical study with 338 women who gave birth at a tertiary hospital. Obstetric and neonatal variables were measured and compared in women submitted and non-submitted to stimulation with oxytocin. Statistics were performed using Chi-square test, Fisher exact test, Student t-test; and crude Odds Ratio with 95% confidence interval were calculated. A p < 0.05 was considered statistically significant. Results: stimulation with oxytocin increases the rates of cesarean sections, epidural anesthesia and intrapartum maternal fever in primiparous and multiparous women. It has also been associated with low pH values of umbilical cord blood and with a shorter duration of the first stage of labor in primiparous women. However, it did not affect the rates of 3rd and 4th degree perineal lacerations, episiotomies, advanced neonatal resuscitation, 5-minute Apgar scores and meconium. Conclusion: stimulation with oxytocin should not be used systematically, but only in specific cases. These findings provide further evidence to health professionals and midwives on the use of oxytocin during labor. Under normal conditions, women should be informed of the possible effects of labor stimulation with oxytocin.
In-house coordination project for organ and tissue procurement: social responsibility and promising results
Authors: Silva Vanessa Silva e , Moura Luciana Carvalho , Martins Luciana Ribeiro , Santos Roberta Cristina Cardoso dos , Schirmer Janine , Roza Bartira de Aguiar
Published: July 2016

Abstract Objectives: to report the results of evaluation regarding changes in the number of potential donor referrals, actual donors, and conversion rates after the implementation of an in-house organ and tissue donation for transplantation coordination project. Methods: epidemiological study, both retrospective and transversal, was performed with organ donation data from the Secretariat of Health for the State and the in-house organ donation coordination project of a beneficent hospital. The data was compared using nonparametric statistical Mann-Whitney test, and the Student's t-test, considering a significance level of 5% (p <0.05). Results: there were statistically significant differences (p < 0.05), before and after the implementation of the project on the number of potential donor notification/month (3.05 - 4.7 ), number of actual donor/month (0.78 to 1.60) and rate of conversion ( 24.7 to 34.8 %). The hospitals 1, 2, 7 and 8 had significant results in potential donor, actual donor or conversion rate. Conclusion: the presence of an in-house coordinator is promising and beneficial, the specialist is important to change the indicators of efficiency, which consequently reduces the waiting lists for organ transplants.
Perfil das alterações vasculares periféricas em dependentes de crack acompanhados em Centro de Atenção Psicossocial para Álcool e Drogas (CAPS-AD)
Authors: Costa Júnior Antônio Fagundes da , Baldaçara Leonardo Rodrigo , Silva Sílvio Alves da , Tavares Ana Célia de Freitas Ramos , Orsolin Ederson de Freitas , Prehl Vinícius Barros , Gondo Fernando Hirohito Beltran , Santana Hernani Lopes
Published: July 2016

Resumo Contexto O consumo de crack é um dos grandes desafios em saúde pública, e o uso dessa droga tem efeitos diretos na saúde de seus usuários. Objetivos Avaliar o perfil das alterações vasculares em pacientes com dependência de crack em Centro de Atenção Psicossocial para Álcool e Drogas (CAPS-AD) e observar os possíveis efeitos vasculares periféricos. Métodos Trata-se de um estudo observacional, descritivo, de corte transversal. Os pacientes da amostra foram submetidos a um questionário objetivo para avaliar questões demográficas, padrão de uso da droga, coexistência de diabetes melito, hipertensão arterial ou tabagismo, exame físico e ecográfico. Os dados foram sumarizados e analisados estatisticamente com teste qui-quadrado ou teste exato de Fisher. Resultados A média de idade da amostra foi de 33,29 (±7,15) anos, e 74% eram do gênero masculino. A média de idade de início de uso da droga foi de 23,4 (±7,78) anos, com tempo médio de uso de 9,58 (±5,64) anos. O consumo médio diário de pedras de crack foi de 21,45 (±8,32) pedras. A alteração de pulsos em membros inferiores foi mais frequente em mulheres. A prevalência do espessamento da parede arterial nos membros inferiores foi de 94,8%. O tempo de uso da droga apresentou associação estatística (p = 0,0096) com alteração do padrão de curva espectral das artérias dos membros inferiores. Conclusões Há alterações vasculares periféricas em usuários de crack. O tempo de uso da droga exerceu um maior impacto nesse sistema, o que sugere associação entre o uso do crack e a diminuição de fluxo arterial.
Trombocitopenia induzida por heparina em paciente com oclusão arterial aguda
Authors: Pimenta Rafael Elias Farres , Yoshida Winston Bonetti , Rollo Hamilton Almeida , Sobreira Marcone Lima , Bertanha Matheus , Mariúba Jamil Victor de Oliveira , Jaldin Rodrigo Gibin , Camargo Paula Angeleli Bueno de
Published: July 2016

Resumo A trombocitopenia induzida por heparina é uma complicação grave da terapêutica anticoagulante com heparina e está associada à formação de anticorpos antifator IV plaquetário. Costuma surgir a partir do quinto dia do tratamento, com queda de pelo menos 50% da contagem plaquetária. Em decorrência da ativação plaquetária concomitante, pode ocorrer quadro de trombose, venosa ou arterial, com repercussões clínicas graves. Apresentamos um caso de paciente portador de síndrome do anticorpo antifosfolípide, com quadro de oclusão arterial aguda, que foi tratado cirurgicamente e recebeu heparina não fracionada no intra e pós-operatório. No quinto dia de tratamento anticoagulante, apresentou queda maior de 50% da contagem de plaquetas em relação à contagem pré-heparina. A suspeita de trombocitopenia induzida por heparina e seus aspectos diagnósticos e terapêuticos serão abordados neste desafio terapêutico.
Topical vs. intravenous administration of tranexamic acid in knee arthroplasty and prevalence of deep venous thrombosis: a randomized clinical trial
Authors: Zekcer Ari , Del Priori Ricardo , Tieppo Clauber , Silva Ricardo Soares da , Severino Nilson Roberto
Published: July 2016

Abstract Background Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative bleeding. Since TXA inhibits fibrinolysis, there is concern that it may increase the risk of thromboembolic events. Objectives To verify the prevalence of deep venous thrombosis (DVT) in patients receiving TXA during total knee arthroplasty and to compare topical with intravenous administration of the drug. Methods All patients admitted for total knee arthroplasty due to primary arthrosis between June and November of 2014 were recruited consecutively. Thirty patients were randomized to a “topical group” (1.5 g TXA diluted in 50ml saline sprayed over the area operated, before tourniquet release), 30 to an “intravenous group” (20mg/kg TXA in 100 ml of saline, given at the same time as anesthesia), and 30 to a control group (100 ml of saline, given at the same time as anesthesia). All patients had duplex ultrasound scans of the legs on the 15th postoperative day. Results Deep venous thrombosis events occurred in five of the 90 patients operated (one out of 30 in the topical group [3.3%], four out of 30 in the control group [13.3%], and zero in the intravenous group). All were confirmed by duplex ultrasound scans and all were asymptomatic. Prevalence rates of DVT were similar between groups (p = 0.112 for control vs. intravenous; p = 0.353 for control vs. topical; and p =1.000 for intravenous vs. topical, according to two-sided exact tests). Conclusions Both topical and intravenous administration of TXA are safe with regard to occurrence of DVT, since the number of DVT cases in patients given TXA was not different to the number in those given placebo.
Achados incidentais de aneurismas torácicos e abdominais
Authors: Góes Junior Adenauer Marinho de Oliveira , Mascarenhas Bárbara Íris , Rodrigues Sofia Cunha , Andrade Mariseth Carvalho de , Franco Reinaldo Sergio Monteiro
Published: July 2016

Resumo Contexto Os aneurismas de aorta abdominal (AAAs) são os mais comuns. A incidência anual de ruptura do AAA é de oito casos por 100.000 habitantes. A detecção incidental pode beneficiar o paciente, desde que o diâmetro seja monitorado e o paciente receba o tratamento adequado. Objetivos Estimar a prevalência do diagnóstico incidental de aneurisma de aorta torácica (AAT) e de AAA em tomografias computadorizadas (TCs); avaliar a prevalência de sexo e idade dos pacientes e determinar quais as artérias acometidas e as características morfológicas dos aneurismas; determinar quais as indicações de TC mais associadas ao diagnóstico incidental de aneurismas. Métodos Estudo descritivo, retrospectivo e randomizado. Critérios de inclusão: pacientes com 50 anos ou mais submetidos a TC de tórax, abdome ou pelve. Critérios de exclusão: acompanhamento ou suspeita diagnóstica de aneurismas. Foram utilizados protocolos com questões sobre dados demográficos e anatômicos. Resultados Foram analisados 1.202 laudos radiológicos. Detectados 27 aneurismas (prevalência de 2,2%). Pacientes: 60% do sexo masculino e 40% do sexo feminino (p < 0,05). Localização: 13 casos (48,2%) na aorta ascendente (AAT); 7 (25,9%) na aorta infrarrenal (AAA); 2 (7,4%) aorta na transição toracoabdominal (ATA); 2 (7,4%) na ilíaca comum; 1 (3,7%) na ilíaca interna; 1 (3,7%) na artéria esplênica; e 1 (3,7%) na artéria renal. Conclusões A maioria dos pacientes foi do sexo masculino (60%); houve maior frequência de AAT (diâmetro médio de 4,1 cm), seguido de AAA (diâmetro médio de 4,0 cm) e ATA (diâmetro médio de 3,9 cm). A principal indicação para a realização de TC associada ao diagnóstico incidental de aneurismas foi em função de sintomas respiratórios.
A geometria dinâmica do círculo de Apolônio
Authors: Oliveira Jr. Reynaldo Lopes de
Published: July 2016

Neste trabalho, apresento uma nova questão referente à aplicação do círculo de Apolônio no contexto do design de games. Ao invés de determinarmos o ponto de encontro a partir das condições iniciais; na nova questão proposta decidiremos previamente o ponto de encontro/interceptação e calcularemos o instante em que o torpedo deve ser lançado. Na questão proposta em [1] o torpedo e o navio partem ao mesmo tempo (em trajetória retilínea) rumo a interceptação. E se esperarmos um certo tempo t para lançarmos o torpedo? Ou então, e se apontarmos o torpedo para uma determinada posição e desejarmos saber em que instante o navio será interceptado nesta posição? Estas são as novas questões trazidas nesta nota.
A lei de Hooke e as molas não-lineares, um estudo de caso
Authors: Aranha Norberto , Oliveira Jr José Martins de , Bellio Luis Oscar , Bonventi Jr Waldemar
Published: July 2016

Neste trabalho pretende-se analisar elementos elásticos com respostas linear e não linear. Foi realizado o estudo comparativo entre três molas helicoidais, sendo uma linear e duas não lineares, e um tubo de látex. O estudo envolveu o levantamento das curvas de força versus distância e seus respectivos ajustes matemáticos para cada elemento elástico. A proposta é apresentar diferentes formas de abordar o tema elasticidade nas aulas de física, visando chamar a atenção do aluno de que a linearidade que trata a lei de Hooke aplica-se apenas para uma pequena faixa de valores de força e que em várias situações os elementos elásticos tem um comportamento não linear, sendo necessário lançar mão de outras relações matemáticas que se ajustem aos dados experimentais.
Os cem anos do átomo de Sommerfeld
Authors: Braga J. P.
Published: July 2016

O presente trabalho discute o modelo do átomo de Sommerfeld não relativístico no contexto da mecânica quântica antiga. No intuito de deixar o trabalho completo são também discutidas as energias da partícula na caixa, rotor rígido e oscilador harmônico. Uma introdução histórica da mecânica quântica antiga e uma discussão qualitativa do correspondente modelo relativístico são também elaborados. O texto apresentado pode ser acompanhado por estudantes de graduação.
Evaluation of the symptoms and treatment prescribed to hospitalized patients
Authors: Roldi Mariana da Silva , Moritz Rachel Duarte
Published: July 2016

Summary Objective: Evaluation of the presence of symptoms and suitability in the treatment of patients admitted to medical wards at HU-UFSC. Identification of patients eligible for palliative care (PC). Method: A prospective cohort study, which evaluated patients in the first 48 hours of hospitalization (D1) and after 48 hours (D2). On D1, palliative performance and symptom assessment scales were applied (PPS/ESAS). The treatment established for the control of detected symptoms was also identified. On D2, the ESAS scale was applied again, and the medical prescription reviewed. When the presence of severe symptoms was found, the attending physician was informed. Patients who presented PPS≤60 were eligible for PC prioritization. For statistical analysis Student’s t and χ2 tests were used. Results: 168 patients were studied. Of these, 26.8% had PPS≤60. PC was described in one medical chart. Patients with mild symptoms reported significant worsening in the second evaluation, especially worsening in pain (32.3%) and well-being (49.3%). Symptoms considered severe showed significant improvement. There was no control of pain reported as moderate. Prescriptions for pain control were predominantly “if necessary”, prevailing the use of non-opioid analgesics and weak opioids. The attending physician was informed of 116 (69%) patients with ESAS score≥4. Conclusion: The control of symptoms, especially those considered mild, was unsatisfactory. Drug prescription was inadequate to control pain, and non-existent for some reported symptoms. There was no adequate prioritization of PC. There is a need for optimization and dissemination of PC among health professionals.
Prevalence of fungemia in a tertiary hospital: Analysis of the last decade
Authors: Castro Luísa Lima , Schütze Manuel , Bücker Daniel Henrique , Vasconcellos Leonardo de Souza
Published: July 2016

Summary Introduction: The prevalence of nosocomial fungemia has increased worldwide, and mortality caused by this disease is high. Objective: To assess progress in the last decade, and the prevalence and profile of fungal agents isolated in blood cultures performed in a tertiary university hospital. Method: All the results of blood cultures processed at Hospital das Clínicas, Universidade Federal de Minas Gerais (HC-UFMG), in the time intervals 2001-2003 and 2011-2013 were analyzed retrospectively. For each three-year period, the number of collected blood cultures, the overall positivity rate and the percentage of fungemia were recorded. In addition, all identified fungal species were cataloged. All blood samples were incubated in the BacT/ALERT® (bioMérieux) automation system. Results: In 2001-2003, 34,822 samples were evaluated, with 5,510 (15.8%) positive results. In 2011-2013, the number of blood cultures processed increased to 55,052 samples, with 4,873 (8.9%) positive results. There was an increase in the number of positive cultures for fungi in the analyzed period (2001-2003: 4.16%; 2011-2013: 5.95%; p<0.001). Among the agents, candidemias were predominant, especially those caused by non-albicans Candida species (2001-2003: 57.64%; 2011-2013: 65.17%; p<0.05). There was also an increase in fungemia caused by other genera (2001-2003: 2.62%; 2011-2013: 4.48%; p<0.01). Conclusion: There was an increase in the prevalence of fungemia in the last decade at HC-UFMG. Although candidemias have been responsible for most of the cases, there has been an increase in fungemias caused by other species.
Profile of pediatric eye trauma at Hospital de Base do Distrito Federal (HBDF), Brasília, Brazil
Authors: Rohr Juliana Tessari Dias , Santos Procópio Miguel dos , Santos Regina Candido Ribeiro dos , Vieira Camila Viana , Fé Lylian Moura , Solano Rodrigo Luis , Reis Túlio Frade , Leão Marcell de Oliveira , Guimarães Vinícius da Costa
Published: July 2016

Summary Objective: To describe the epidemiological profile of ocular trauma in children at the HBDF emergency department. Method: Descriptive, cross-sectional study. We evaluated 103 cases of ocular trauma in children less than 15 years between July 2012 and January 2013. The factors evaluated through semi-structured questionnaire available online were: age, gender, adult supervision, mechanism, type of trauma, time and place, site and nature of injury, visual acuity, need for hospitalization and/or surgery, type of surgery, mother’s level of education, and family income. Results: The average age of patients studied was 7.5 years. Boys (68%) predominate in all age groups. Blunt trauma prevailed (55.3%), followed by open (20%). Most of the cases occurred at home, 14 to 20 hours before seeking hospital care. The most common causes were: wood, stone, bicycle, broken glass, and falls. The cornea was affected in 54%. Visual acuity was ≥20/40 in 68.9%. Primary repair of the eye wall was indicated in 70.37% (p-value=0.022). Open traumas were more severe (p-value=0.005) and had more need for intervention (p-value=0.000). The injuries occurred despite the presence of adult supervision in 54% (p-value=0.002). The most severe injuries predominated in the age range 7-15 years (p=0.001). Conclusion: Ocular trauma was more frequent among boys. The mechanisms of injury are the most diverse, and prevail at home. Blunt trauma prevails, but the visual impact is due to open trauma. Programs of prevention and education on child ocular trauma are needed.
Trends of teenage pregnancy in Brazil, 2000-2011
Authors: Vaz Raquel Ferreira , Monteiro Denise Leite Maia , Rodrigues Nádia Cristina Pinheiro
Published: July 2016

Summary Objective: To evaluate the frequency of teenage pregnancy in Brazil, from 2000 to 2011, in all five Brazilian macroregions and age groups (10-14 and 15-19 years), correlating it with the human development index (HDI). Method: Descriptive epidemiological study, with cross-sectional design, performed by searching the database of the National Health System (Datasus), using information from the Information System (Sinasc). Results: There was a decrease in the percentage of live births (LB) from teenage mothers (10-19 years) in Brazil (23.5 % in 2000 to 19.2 % in 2011). This reduction was observed in all Brazilian macroregions in the group of mothers aged 15 to 19 years. The number of LB increased by 5.0% among mothers aged 10-14 years (increase in the North and Northeast and decline in the other macroregions). The proportion of LB shows an inversely proportional trend to HDI score, with the Southeast having the highest HDI and the lowest proportion of LB to teenage mothers in the country. Conclusion: Brazil shows a decline in the percentage of LB to adolescent mothers, tending to be inversely related to HDI score. It is important to empower strategies to address the problem, so that teenage pregnancy is seen as a personal decision rather than the result of a lack of policies targeting adolescent health.
Spatial data analysis and the use of maps in scientific health articles
Authors: Nucci Luciana Bertoldi , Souccar Patrick Theodore , Castilho Silvia Diez
Published: July 2016

Summary Introduction: Despite the growing number of studies with a characteristic element of spatial analysis, the application of the techniques is not always clear and its continuity in epidemiological studies requires careful evaluation. Objective: To verify the spread and use of those processes in national and international scientific papers. Method: An assessment was made of periodicals according to the impact index. Among 8,281 journals surveyed, four national and four international were selected, of which 1,274 articles were analyzed regarding the presence or absence of spatial analysis techniques. Results: Just over 10% of articles published in 2011 in high impact journals, both national and international, showed some element of geographical location. Conclusion: Although these percentages vary greatly from one journal to another, denoting different publication profiles, we consider this percentage as an indication that location variables have become an important factor in studies of health.
Family history of cardiovascular disease and non-HDL cholesterol in prepubescent non-obese children
Authors: Strufaldi Maria Wany Louzada , Souza Fabíola Isabel Suano de , Puccini Rosana Fiorini , Franco Maria do Carmo Pinho
Published: July 2016

Summary Objective: To describe the values of non-HDL cholesterol (NHDL-c) and the frequency of a family history of early cardiovascular disease (family HCVD) in healthy prepubescent children. Analyze the association between NHDL-c and family HCVD, and possible associations with other risk factors for cardiovascular disease (CVD). Method: Cross-sectional study including 269 prepubescent (aged 6-10 years) schoolchildren with a normal body mass index (+1SD-2SD). Data collected: Family HCVD; weight and height, waist circumference and systemic blood pressure; lipid profile (total cholesterol TC, HDL-c, triglycerides and LDL-c), NHDL-c calculation (CT-HDL-c, cut-off = 145 mg/dL) and insulin resistance (HOMA-IR). Results: High levels were found for NHDL-c in 10 (3.7%) of these schoolchildren, and family early HCVD was found in 46 (17.1%) of them. There was a weak association between family HCVD and NHDL-c (Cramer’s-V-test = 0.120; p=0.050). Among the children with NHDL-c≥145 mg/dL, 4 (40%) have family HCVD. The presence of family HCVD was not associated with the variables being studied. The variables independently associated with NHDL-c ≥ 145 mg/dL were: HOMA-IR (OR=1.7; 95CI 1.1-2.6) and diastolic blood pressure (OR=1.1; 95CI 1.02-1.2). Conclusion: NHDL-c values were associated with blood pressure and insulin resistance. Family HCVD was not associated with other classic risk factors for CVD, even though the frequency found was five times higher than that of high NHDL-c.