bluuebunny/crossref_metadata_2025 huggingface dataset:
Tailoring Metal–Oxide Interfaces via Selectively CeO2-Decorated Pd Nanocatalysts with Enhanced Catalytic Performance
Authors: Liu Ziwen , Zhang Guizhen , Niu Lijuan , Sun Zaicheng , Li Zhenguo , He Hong
Published: January 2025

Metal–oxide interfaces play a prominent role in heterogeneous catalysis. Tailoring the metal–oxide interfaces effectively enhance the catalytic activities and thermal stability of noble metal catalysts. In this work, polyvinyl alcohol-protected reduction and L-arginine induction methods are adopted to prepare Pd catalysts (Pd/Al2O3-xCeO2) that are selectively decorated by CeO2, which form core–shell-like structures and generate more Pd-CeO2 interfacial sites, so that the three-way catalytic activity of Pd/Al2O3-xCeO2 catalysts is obviously significantly enhanced due to more adsorption oxygen at the interface of Pd-CeO2 and good low-temperature reducibility. At the moment, the Pd/Al2O3-xCeO2 catalysts exhibit excellent thermal stability after being calcined at 900 °C for 5 h, owing to the Pd species being highly redispersed on CeO2 and part of the Pd species being incorporated into the lattice of CeO2. This is a major reason for the Pd/Al2O3-xCeO2 catalysts to maintain high catalytic activity after aging at high temperatures. It is concluded that the metal–oxide interfaces and the interaction between Pd NPs and CeO2 are responsible for the excellent catalytic performance and stability of Pd/Al2O3-xCeO2 catalysts in three-way reactions.
The Role of Somatic Mutations in Ischemic Stroke: CHIP’s Impact on Vascular Health
Authors: Kinzhebay Aiman , Salybekov Amankeldi A.
Published: January 2025

Clonal hematopoiesis of indeterminate potential (CHIP) is increasingly recognized as a significant contributor to ischemic stroke and other cardiovascular diseases due to its association with somatic mutations in hematopoietic cells. These mutations, notably in genes like DNMT3A, TET2, and JAK2, induce pro-inflammatory and pro-atherosclerotic processes, promoting vascular damage and stroke risk. With the prevalence of CHIP rising with age, its presence correlates with higher mortality and morbidity rates in ischemic stroke patients. This article explores the mechanisms through which CHIP influences vascular aging and stroke, emphasizing its potential as a biomarker for early risk stratification and a target for therapeutic intervention. The findings highlight the necessity of integrating CHIP status in clinical evaluations to better predict outcomes and personalize treatment strategies in stroke management.
Efficiency of Nitrate Removal from Groundwater by Adsorption on Raw and Treated Bentonite
Authors: Kheliel Oussama , Youcef Leila , Youcef Soufiane , Bouaziz Mohamed Ghrissi , Chebbi Meriem
Published: January 2025

The objective of this study was to treat groundwaters with a high initial nitrate (NO3−) content (125 mg/L, and 177 mg/L) by adsorption onto a local bentonite in its raw state (RB), treated with a ratio of H2SO4/bentonite = 0.2 (B0.2), and another treated with a ratio of H2SO4/bentonite = 0.6 (B0.6). Non-linear modelling of the nitrate adsorption kinetics of two water samples showed the pseudo-first-order model was the best fit, confirming that nitrate retention on each adsorbent was due to chemisorption. The intra-particle diffusion curves were multi-linear, indicating that there are other mechanisms influencing nitrate ion adsorption on bentonite than intra-particle diffusion. The effectiveness of the adsorbents tested was in the following order: B0.6 > B0.2 > RB. This finding demonstrates that acid activation of the clay improves its characteristics. The optimal adsorbent dose was found to be 1 g/L after changing the bentonite dose from 0.1 to 4 g/L. The pH of the treatment affects nitrate removal rates. The greatest results are achieved at pH levels close to 6. It also appears that the treatment was more effective for water with low initial nitrate levels.
High β-Glucan Whole Grain Barley Reduces Postprandial Glycemic Response in Healthy Adults—Part One of a Randomized Controlled Trial
Authors: Kellogg Julianne A. , Monsivais Pablo , Murphy Kevin M. , Perrigue Martine M.
Published: January 2025

Background/Objectives: The effects of sweetened and unsweetened high β-glucan whole grain barley on postprandial blood glucose response in normoglycemic human subjects were evaluated in a randomized, controlled, crossover clinical trial. Methods: Sixteen healthy, over-night fasted participants were studied on four or eight separate occasions. Participants consumed an unsweetened preload condition (n = 16): white glutinous rice (WR; 0 g β-glucan), low β-glucan barley (LB; ~4 g), medium β-glucan barley (MB; ~5 g), or high β-glucan barley (HB; ~6 g); or a sweetened condition with high fructose corn syrup (HFCS; n = 8): WR + 50 g HFCS, LB + 50 g HFCS, MB + 50 g HFCS, or HB + 50 g HFCS. After consuming the preload as a breakfast food, participants self-administered blood glucose tests every 15 min for four hours. Results: In both sweetened and unsweetened conditions, higher β-glucan content was associated with lower blood glucose peak response and incremental area under the curve estimates (iAUC). In comparison to the unsweetened conditions, the sweetened conditions resulted in less prominent decreases in mean blood glucose response and iAUC blood glucose as β-glucan content increased. Conclusions: By attenuating postprandial glycemic response, high β-glucan whole grain barley foods could play a role in helping to control blood glucose.
Evaluating Bioactive-Substance-Based Interventions for Adults with MASLD: Results from a Systematic Scoping Review
Authors: Handu Deepa , Stote Kim , Piemonte Tami
Published: January 2025

Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a chronic condition affecting a broad population. This review aimed to identify and summarize the current evidence on bioactive-substance-based interventions for adults with MASLD, formerly known as nonalcoholic fatty liver disease (NAFLD), covering publications from 2000 to 2023. Methods: A search was conducted across six databases (MEDLINE, CINAHL, Cochrane CENTRAL, Cochrane Database of Systematic Reviews, Food Science Source, and SPORTDiscus) for randomized controlled trials and other study types (e.g., prospective cohort studies and systematic reviews), reflecting the scoping nature of this review. The search was limited to studies in adults (>18 years old), with an intervention of interest and at least one comparator group. Results: A total of 4572 articles were retrieved, with 201 full-text articles screened for eligibility. Of these, 131 primary studies and 49 systematic reviews were included in the scoping review. The most studied bioactive substances were Curcumin (Turmeric) (n = 25), Silymarin (Milk Thistle) (n = 17), Resveratrol (n = 10), Coffee (n = 7), Green Tea (n = 5), and Berberine (n = 5 each). Moreover, 46 studies reported on 36 other bioactive substances with 2 or fewer articles each. Among the included systematic reviews, 13 focused on Curcumin, 12 on Coffee or Tea, 10 on bioactive substance combinations, 6 on Resveratrol, and 2 each on Silymarin and Artichoke Leaf. The included studies showed substantial heterogeneity in reported outcomes, which primarily focused on hepatic health, body weight, adverse events, glycemic control, blood lipids, and body composition. Conclusions: This scoping review highlights a range of bioactive substances used in the treatment of MASLD. While evidence is abundant for bioactive substances like Curcumin and Silymarin, further research and synthesis of findings is necessary to establish the clinical efficacy of all bioactive substances.
Pyroptosis: A Novel Therapeutic Target for Bioactive Compounds in Human Disease Treatment? A Narrative Review
Authors: Yang Bei , Qi Zexiu , Armas Diaz Yasmany , Cassotta Manuela , Grosso Giuseppe , Cianciosi Danila , Zhang Di , Zou Xiaobo , Quiles José L. , Battino Maurizio , Giampieri Francesca
Published: January 2025

Background/Objectives: Bioactive compounds possess the ability to maintain health and improve diseases by regulating inflammation and cell death processes. Pyroptosis is programmed cell death related to inflammation and exerts a critical role in the development and progression of different types of diseases. This narrative review aims to investigate and discuss the effects of dietary bioactive compounds on pyroptosis in different common human pathologies, such as inflammatory disease, bacterial infection, injury disease, cancer, diabetes and heart disease, etc. Method: Studies published in the major databases until December 2024 in English were considered, for a total of 50 papers. Results: The current evidence demonstrated that the bioactive compounds are able to regulate the pyroptosis process by modulating different inflammasome sensors (NLRP1, NLRP3, and AIM2), caspase family proteins (caspase-1, caspase-3, and caspase-11), and gasdermins (GSDMD and GSDME) in many pathological conditions related to inflammation, including cancer and cardiovascular diseases. Conclusions: Bioactive compounds have powerful potential to be the candidate drug for pyroptosis modulation in inflammatory diseases, even if more clinical studies are needed to confirm the effects and establish efficient doses for humans.
Application of Global Warming Potential Star (GWP*) Values to the AUSNUT 2011-13 Food Composition Database: Creation of the GWP*-AUSNUT 2011-13 Database
Authors: Neale Elizabeth , Balvert Troy , Crinnion Hannah , Craddock Joel , Lambert Kelly , Charlton Karen
Published: January 2025

Background/Objectives: The Global Warming Potential Star (GWP*) refers to the amount of carbon dioxide equivalents produced by food items, with values available for n = 232 Australian food products. The aim of this study was to apply GWP* values to the AUSNUT 2011-13 food composition database to facilitate the calculation of the climate footprint of Australian dietary data. Methods: To create the GWP*-AUSNUT 2011-13 database, all n = 5740 food and beverage items in AUSNUT 2011-13 were reviewed and GWP* values applied or calculated via a systematic approach. Direct or approximate matches to a single GWP* value were prioritised. GWP* values were then calculated for composite foods with multiple ingredients. Finally, GWP* values were approximated based on food group, adjusted using other GWP* values, or foods were excluded if no appropriate match could be found. Results: A total of n = 5502 (95.85%) AUSNUT 2011-13 foods were matched to a GWP* value, with the majority requiring calculation based on multiple ingredients. Mean ± standard deviation GWP* values ranged from 0.18 ± 0.12 kg CO2e/kg (‘Dairy and meat substitutes’) to 5.63 ± 7.55 kg CO2e/kg (‘Meat, poultry and game products and dishes’). Conclusions: The GWP*-AUSNUT 2011-13 database can be applied to Australian dietary data to identify the climate footprint of different dietary patterns or to provide insight into dietary changes required to decrease greenhouse gas emissions. Future research is now required to develop new GWP* values for a broader range of foods and to update this database when new Australian food composition databases are released.
Factors Associated with Workplace Injuries Among Shift Work Nurses: A Cross-Sectional Study in an Ecuadorian Sample
Authors: Prados Germán , Mendoza-Vinces Ángela , Holguín Martha , Cambil-Martín Jacobo , Fernández-Puerta Laura
Published: January 2025

Background/Objectives: Shift work schedules and mental and physical workloads affect the sleep homeostasis of nurses, increasing the risk of occupational injuries. This study aimed to investigate the relationship between sleep disturbances caused by shift schedules and the occurrence of needlestick and sharps injuries (NSIs) among nurses, considering significant worker and occupational factors. Methods: A total of 348 nurses from five hospitals of Santiago de Guayaquil, Ecuador, participated in this cross-sectional survey. Data on sociodemographic and occupational characteristics, work schedules, and NSI incidents during the previous six months were collected. Emotional status, sleepiness, and insomnia symptoms were assessed using validated questionnaires. Additionally, nurses with night shifts (fixed or rotating) were specifically assessed to estimate the relationship between NSIs and insomnia or sleepiness symptoms related to these types of shift work using logistic regression analyses. Results: Nurses whose schedule included night shifts showed a higher prevalence of NSIs than those with other shifts (33.2% vs. 29.0%; p < 0.05). High levels of depression, anxiety, and stress were associated with having had an NSI in the previous six months. Logistic regression showed that female sex (adjusted odds ratio, aOR 4.62, 95% CI: 1.65–12.97), less experience in the current clinical setting (aOR 3.12, 95% CI: 1.46–6.57), the use of psychotropic drugs (aOR 4.46, 95% CI: 1.51–13.17), and insomnia and sleepiness symptoms due to shift work (aOR 2.61, 95% CI: 1.15–5.91) increased NSI risk among nurses with night shifts. Conclusions: There is an acute need to explore the complex relationship between sleep troubles linked to shift work schedules, occupational factors, and the risk of occupational injuries and propose preventive strategies for enhancing nurses’ sleep health and workplace safety.
Pharmacokinetic and Pharmacodynamic Study of Folic Acid-Modified Chitosan–Stearic Acid Nanomicelles Loaded with Tetrandrine for Rheumatoid Arthritis
Authors: Ma Shuai , Xue Fei , Yang Lan , Chen Long , Liu Pei , Chang Jinhua , Wang Ruxing
Published: January 2025

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease, and it is currently incurable. Tetrandrine (TET) has an obvious curative effect with therapeutic efficacy on RA, but its use is limited due to its poor water-solubility and bioavailability. Therefore, TET-loaded nanomicelles modified with chitosan, stearic acid, and folic acid (FCST) was prepared in the study, and the pharmacokinetics and pharmacodynamics were studied. Methods: The plasma concentrations of FCST and TET were measured by the PLC-MS/MS method at different times, and the pharmacokinetic parameters were calculated. A collagen-induced arthritis (CIA) model was established with rats. On the 16th day after the first immunization, 50 rats were randomized into five groups with 10 rats in each group according to the arthritis score. The drugs were administered by intraperitoneal injection for 30 days. The swelling degree and joint score of the rats were tested during each administration. In addition, the pro-inflammatory factors IL-1β, IL-6, IL-17, and TNF-α in the serum of the rats were tested by an ELISA kit, and their joints were examined by histopathology. Results: Pharmacokinetic studies showed that the AUC0–72h of FCST was 1.93 times that of TET. FCST demonstrated higher bioavailability compared to TET (p < 0.05). Pharmacodynamic studies demonstrated that FCST had significant anti-inflammatory effects, and its anti-inflammatory activity was stronger compared to the same dose of TET, as evidenced by measuring toe thickness and observing toe appearance. It significantly reduced the expression of IL-1, IL-6, IL-17, and TNF-α in rats with rheumatoid arthritis (p < 0.05). Conclusions: FCST can significantly improve bioavailability and has a significant therapeutic effect on rheumatoid arthritis.
Current Status of Pulsatilla patens in Latvia—Population Size, Demographic and Seed Viability Indicators, Soil Parameters and Their Relationships
Authors: Kļaviņa Dace , Osvalde Anita , Tabors Guntis , Jakobsone Gunta
Published: January 2025

Pulsatilla patens (L.) Mill. (Eastern pasque flower) is classified as a highly endangered and declining species in Europe. The present research assessed the current status of P. patens in Latvia by collecting data on its distribution in historical places, Natura 2000 territories, and other areas, largely covering the entire country. We aimed to analyze the relationships between P. patens populations size, demographic indicators, and soil parameters, in order to gain knowledge on the impact of local ecological factors and optimal growth conditions, which are important for conservation and potential reintroduction. Although P. patens was not detected in more than a third of the surveyed 624 locations, more than 18 thousand individuals were recorded. Our results indicate that optimal growth conditions for P. patens occurred near highways, forest roads, and paths, that is, in places with reduced competition from other species and improved lighting conditions. The seed viability ranging from 22% to 62% can be considered potentially sufficient for the continuation of the species if enough flowering plants and moss-free spaces for germination are maintained. Although P. patens tolerates a broad soil pH range, in Latvia this species mainly grows in acidic sandy soils with an average pHKCl of 4.07. The soil parameters that most strongly positively correlated with P. patens regional population size and performance included higher soil pH level and plant available nutrient content, particularly P, K, Ca, Mg, Mn and B. Increased soil P and Mn levels significantly enhanced flowering, while high organic matter content could be associated with reduced population sizes. Despite its still large current population, long-term risks remain without active management. Conservation measures, such as creating open soil areas, where vegetation is removed and shading is reduced, are necessary to mitigate population decline.
Theobroma mariae: Bioactive Compound-Rich Flowers
Authors: Silva Laila Y. S. , Cavalcante Débora N. , Oliveira Edinilze S. C. , Salvador Andreia M. , Pereira Zilanir C. , Consentini Julia C. C. , Furlaneto Gabriela , Campelo Pedro H. , Sanches Edgar A. , Azevedo Luciana , Bezerra Jaqueline de A.
Published: January 2025

Edible flowers have gained attention as unconventional food sources due to their nutritional and functional properties. This study provides novel information on the chemical composition, cytotoxicity and antiproliferative effects of Theobroma mariae flowers. The objective of this paper was to identify bioactive compounds in its flowers using one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS). The phenolic fraction of the flowers revealed bioactive compounds such as hyperoside, guaijaverin, astragalin, juglalin, and kaempferol. The results confirmed the potential of T. mariae flowers as a source of phenolic compounds, emphasizing their feasibility for possible applications in the development of functional foods. Moreover, the antiproliferative assay demonstrated that the phenolic fraction inhibits cell proliferation (GI50) while presenting low cytotoxicity in both cancer and normal cells.
Biochar Nanoparticles Reduce Ciprofloxacin Accumulation and Restore Growth and Hormonal Balance in Rice Seedlings
Authors: Chen Xiaohan , Chen Jieyu , Zhang Yanhong , Ling Chen , Shen Yu
Published: January 2025

Ciprofloxacin (CIP), a widely used fluoroquinolone antibiotic, poses a growing environmental concern due to its persistence in agricultural soils and potential adverse effects on crop production. While previous studies have documented CIP’s negative impacts on plant growth, effective strategies to protect crops from antibiotic stress remain limited. Biochar-based approaches show promise, but their application at the nanoscale for antibiotic stress management is largely unexplored. This study demonstrates how biochar nanoparticles (BNPs) effectively mitigate CIP-induced stress in rice seedlings through adsorption mechanisms. Rice seedlings were treated with 5 and 10 mg L−1 CIP, with and without 0.2 g L−1 BNPs. Results showed that CIP significantly disrupted plant growth, decreasing shoot length by 20.5% and root length by 45.2%, along with reduced biomass. Application of BNPs effectively reduced CIP bioavailability by over 80%, leading to a decreased CIP accumulation of 49.7% in shoots and 33.1% in roots. The addition of BNPs mitigated these growth impacts by restoring shoot length to 98.2% of control levels at 5 mg L−1 CIP and improving root growth and biomass accumulation. BNPs also mitigated CIP-induced hormone imbalance, evidenced by a recovery in IAA levels by 8.9%, an increase in 6-BA by 152.6%, and an enhancement in SA levels by 12.7–13.6%. These findings demonstrate the significant potential of nanoscale biochar in reducing antibiotic stress in agricultural systems and provide insights into plant responses under these conditions. This research offers a promising strategy for enhancing crop resilience in areas affected by pharmaceutical pollutants.
Effect of Exogenous γ-Aminobutyric Acid (GABA) on the Growth, Photosynthetic Pigment, Antioxidant and GABA Metabolism of Festuca arundinacea (Tall Fescues) Under Cadmium Stress
Authors: Geng Wan , Zhang Yangyang , Li Caihua , Song Guilong , Shi Shengqing
Published: January 2025

γ-Aminobutyric acid (GABA), an endogenous amino acid widely found in living organisms, has important functions in plants such as regulating growth and development, maintaining carbon and nitrogen nutrient balance, and coping with adversity. In this study, we investigated the effects of exogenous 0.5 mmol/L GABA on the growth, antioxidant metabolism, and GABA shunt metabolism of tall fescue under 20 μmol/L Cd stress, using tall fescue (Festuca arundinacea) ‘Ruby II’ under hydroponics conditions. The results showed that (1) applying GABA for 3, 7, 11, and 15 d under Cd stress inhibited Cd transport from roots to leaves and promoted plant height, alleviating the effects of Cd stress on plant growth. (2) Exogenous 0.5 mmol/L GABA had an interesting regulatory effect on the activation of the antioxidant enzyme system induced by stress at different stages, which was accompanied by a decrease in malondialdehyde (MDA) contents and alleviated the degree of cell membrane lipid peroxidation under cadmium stress. Specifically, peroxidase (POD) enzyme activity reactions initially responded on the 3rd and 7th days of stress, and the changes in catalase (CAT) enzyme activities concentrated on the 11th and 15th days of the later stage. Ascorbate peroxidase (APX) enzyme was active throughout the whole stress period in the roots. Multiple factorial analyses further proved that the antioxidant pathway strongly influenced the survival and growth of tall fescue under stress in the presence of GABA. (3) Application of exogenous GABA activated the branching pathway for GABA synthesis from Glu decarboxylation (GABA shunt) with a higher contribution in the leaves, which induced changes in glutamate content, and plants maintained a higher endogenous GABA content and signal to regulate the plant antioxidant system and reduce cell membrane damage, thus improving the tolerance of plants to Cd stress.
From Recognition to Response: Resistance–Effector Gene Interactions in the Brassica napus and Leptosphaeria maculans Patho-System
Authors: Qayyum Zuhra , Thomas William J. W. , Amas Junrey C. , Pazos-Navarro Maria , Batley Jacqueline
Published: January 2025

Blackleg disease, caused by the hemibiotrophic fungal pathogen Leptosphaeria maculans, poses a serious threat to Brassica crops and requires a broad understanding of the plant defence mechanisms. The Brassica. napus-L. maculans pathosystem provides a useful model to understand plant resistance response to hemibiotrophs. This review aims to explain the mechanisms underlying R-Avr interaction, signalling cascades, and the hypersensitive response (HR) produced by B. napus towards L. maculans, causing local cell death that restricts the pathogen to the site of infection. The role of transcription factors is pivotal to the process of HR, coordinating the regulation of genes involved in pathogen recognition and the activation of SA responsive genes and production of secondary metabolites. The R-Avr interaction signalling cascade involves production of reactive oxygen species (ROS), calcium ion influx, Salicylic acid (SA) hormonal signalling and mitogen activated protein kinases (MAPKs), which are critical in the HR in B. napus. The in-depth understanding of molecular signalling pathway of the R-Avr interaction between B. napus-L. maculans pathosystem provides valuable information for future research endeavours regarding enhancing disease resistance in Brassica crops.
Thermal Insulating and Mechanically Strong Polyimide Aerogel Composites Reinforced by Polyhedral Oligomeric Silsesquioxane-Grafted Carbon Nanotubes
Authors: Wang Yating , Yang Ruirui , Zhang Zhe , Shan Zicheng , Zhang Liying
Published: January 2025

In the ship industry, developing thermal insulation materials with exceptional high-temperature resistance, structural stability and light weight is essential. Herein, polyimide (PI) composite aerogels were synthesized. Carbon nanotubes (CNTs) introduced cross-linking structures within the aerogel matrix, effectively reducing shrinkage and forming micrometer-scale pores. Furthermore, the rigid cage-like structure of polyhedral oligomeric silsesquioxane (POSS) generated additional nanoscale pores. This multiscale pore structure enhanced both compressive strength and thermal insulation properties. The PI-CNT-POSS composite aerogel with a 2 wt% CNT content (PI-CP2) demonstrated outstanding overall performance, with compressive strength, modulus and thermal conductivity values of 167.7 KPa, 360.3 Kpa and 40.6 mW/(m·K), respectively, possessing remarkable advantages over the neat PI aerogel. Consequently, this PI composite aerogel can be used as a promising material for heat management in complex environments.
From Waste to Worth: Innovative Pyrolysis of Textile Waste into Microporous Carbons for Enhanced Environmental Sustainability
Authors: Anceschi Anastasia , Trotta Francesco , Zoccola Marina , Caldera Fabrizio , Magnacca Giuliana , Patrucco Alessia
Published: January 2025

The generation of synthetic textile waste is a growing global concern, with an unsustainable rate of expansion. This study addresses the growing issue of synthetic textile waste by converting polyester–polyurethane (PET-PU) post-industrial scraps into microporous carbon materials, which can be utilized for wastewater treatment. Using a straightforward pyrolysis process, we achieved a high specific surface area (632 m2/g) and narrow porosity range (2–10 Å) without requiring chemical activation. The produced carbon materials effectively adsorbed methylene blue and orange II dyes, with maximum adsorption capacities of 169.49 mg/g and 147.56 mg/g, respectively. Kinetic studies demonstrated that adsorption followed a pseudo-second-order model, indicating strong interactions between the adsorbent and dyes. Regeneration tests showed that the C-PET-PU could be reused for multiple cycles with over 85% retention of its original adsorption capacity. Preliminary life cycle assessment (LCA) and life cycle cost (LCC) analysis highlighted the environmental and economic advantages of this upcycling approach, showing a reduced global warming potential and a production cost of approximately 1.65 EUR/kg. These findings suggest that transforming PET-PU waste into valuable adsorbents provides a sustainable solution for the circular economy and highlights the potential for broader applications in environmental remediation.
The Study of the Common Rail Pipe Geometrical Parameters on Fuel Flow and Fuel Pressure Characteristics
Authors: Li Ruichuan , Chen Lanzheng , Li Zhengyu , Yuan Wentao , Xu Jikang
Published: January 2025

The influence of the geometric parameters of the common rail pipe on the in-rail fuel flow and pressure is a key issue in the study of high-pressure common rail systems. In this study, based on the principle of fluid dynamics, the effects of the geometric parameters of the common rail pipe inlet on the fuel flow characteristics and pressure distribution in the common rail pipe are analyzed using a combination of numerical simulation and experiment. It was found that the best pressure stabilization was achieved when the fuel inlet was conical with an angle of 120°, which indicates that both the geometry and angle of the fuel inlet have a significant effect on the fuel flow in the common rail pipe. The optimized design in this study has reduced the rail pressure fluctuation value by 3.3 MPa compared to the initial geometry parameters. It is expected to play a role in improving fuel efficiency as well as enhancing system reliability.
A Lightweight Dynamically Enhanced Network for Wildfire Smoke Detection in Transmission Line Channels
Authors: Zhang Yu , Jiao Yangyang , Dou Yinke , Zhao Liangliang , Liu Qiang , Zuo Guangyu
Published: January 2025

In view of the problems that mean that existing detection networks are not effective in detecting dynamic targets such as wildfire smoke, a lightweight dynamically enhanced transmission line channel wildfire smoke detection network LDENet is proposed. Firstly, a Dynamic Lightweight Conv Module (DLCM) is devised within the backbone network of YOLOv8 to enhance the perception of flames and smoke through dynamic convolution. Then, the Ghost Module is used to lightweight the model. DLCM reduces the number of model parameters and improves the accuracy of wildfire smoke detection. Then, the DySample upsampling operator is used in the upsampling part to make the image generation more accurate with very few parameters. Finally, in the course of the training process, the loss function is improved. EMASlideLoss is used to improve detection ability for small targets, and the Shape-IoU loss function is used to optimize the shape of wildfires and smoke. Experiments are conducted on wildfire and smoke datasets, and the final mAP50 is 86.6%, which is 1.5% higher than YOLOv8, and the number of parameters is decreased by 29.7%. The experimental findings demonstrate that LDENet is capable of effectively detecting wildfire smoke and ensuring the safety of transmission line corridors.
Highly Efficient Recovery of Bioactive Puerarin from Roots of Pueraria lobata Using Generally Recognized as Safe Solvents
Authors: Yang Eunjeong , Kwon Hyeok Ki , Lee Jeongho , Kim Seunghee , Lee Giwon , Lee Taek , Chun Youngsang , Lee Soo Kweon , Yoo Hah Young , Park Chulhwan
Published: January 2025

Puerarin (daidzein-8-C-glucoside), one of the bioactive isoflavones, has attracted attention in various industries due to its excellent pharmacological effects such as antioxidant effect, estrogen-like activity, reduction of blood sugar, and neuroprotective effect. Puerarin is most abundantly found in the roots of Pueraria lobata (RPL) among various biomass sources. To improve the utilization feasibility of puerarin, a high-yield extraction process should be designed for RPL. This study aimed to optimize the extraction process to more efficiently recover puerarin from RPL while using generally recognized as safe solvents as extraction solvents, considering the potential industrial applications of puerarin. The extraction variables were optimized by the one-factor-at-a-time method, response surface methodology, and time profiling study. As a result, puerarin yield was achieved at 60.56 mg/g biomass under optimal conditions (ethanol concentration of 46.06%, extraction temperature of 65.02 °C, ratio of extraction solvent to biomass of 11.50 mL/g, and extraction time of 22 min). High puerarin yield achieved in this study contributed to improving the industrial applicability of puerarin.
The Effect of Yellowing on the Corrosion Resistance of Chromium-Free Fingerprint-Resistant Hot-Dip Al-Zn-Coated Steel
Authors: Qiao Degao , Li Jian , Tang Xingchang , Shi Yongjing , Wang Yi , Cao Youzhi , Zhang Zhengqian , Li Yang , Yuan Xiaofeng , Zhang Deyi
Published: January 2025

Inorganic/organic composite passivation film can significantly improve the corrosion resistance performance of hot-dip Al-Zn-coated steel. However, yellowing of the passivation film always leads to obvious performance degradation in corrosion resistance. Investigating the yellowing mechanism of the passivation film and its impact on corrosion resistance would provide a foundation for enhancing its yellowing resistance property. This study primarily focuses on the yellowing mechanism of the passivation film based on the copolymer of N-vinylpyrrolidone and N-vinylcaprolactam. It is found that the oxidation and semi-carbonization of butyramide and valeroamide generated by C–N bond cleavage in the copolymer at high temperatures are responsible for the yellowing of the passivation film. The cracking of the passivation film caused by yellowing degree exposes more of the bare Al-Zn coating, further accelerating the degradation in the corrosion resistance. Additionally, it is observed that the impact of yellowing on the corrosion resistance is negligible when the color difference (ΔE*) caused by yellowing is less than 3.0, whereas ΔE* values above 3.0 result in rapid degradation in the corrosion resistance of the passivation film. The formula y = 0.77 − 0.07x + 0.023x2 + 0.0039x3 effectively expresses the relationship between corrosion area (y) and ΔE* (x) (R2 = 0.995).
In-Situ Stress Prediction of Deep Coal Reservoir Considering Anisotropy: A Case Study of the North-Central Zijinshan Block, North China
Authors: Li Hao , Wang Hui , Zhang Kaichao , Jiang Ke , Zhang Xiaobin , Sun Xiaolei , Qiu Yongkai , Cai Yidong
Published: January 2025

Hydraulic fracturing can significantly enhance coalbed methane production, with in-situ stress playing a crucial role in this process. Our study focuses on calculating in-situ stress in the deep 8+9# coal seam in the north-central Zijinshan block. Leveraging data from acoustic logging and hydraulic fracturing tests, we developed a stress prediction model tailored to the area’s geology. We analyzed stress’s impact on fracturing behavior and the origins of mechanical anisotropy in deep coal reservoirs using μ-CT imaging. Our results show that the Anderson-modified model, accounting for transverse isotropy, offers greater accuracy and applicability than traditional models. The study area exhibits a normal faulting stress regime with significant stress contrasts and maximum horizontal principal stress aligned with the east-west geological stress direction. After hydraulic fracturing, fractures form a complex fracture system resembling elongated ellipses in the coal reservoir, primarily extending in the vertical direction. To control fracture height and prevent penetration through the roof and floor, regulatory measures are essential. μ-CT analysis revealed the distribution of primary fractures, pores, and minerals in the coal, contributing to mechanical anisotropy. This research advances CBM development in the Zijinshan block and similar regions by refining stress prediction and fracturing propagation methods.
Stress State and Fatigue Life Assessment of the Bolts at the Outlet End of Fracturing Pump
Authors: Liu Haibo , Wang Xiaogang , Wang Yuanyuan , Shi Xian , Tian Wang , Wang Bingsheng , Sun Rui
Published: January 2025

The fracturing pump serves as a critical piece of equipment in enhancing oil and gas recovery rates. However, under the coupled action of high-pressure fluid pulsation circulation in the pump body and the vibration of fracturing equipment, the bolts connecting the fracturing pump and fracturing manifold flange are prone to fatigue failure. In this paper, a three-dimensional finite-element model of the threaded bolt connection structure at the fracturing pump outlet end with a fine thread structure was established, and the measured vibrational displacement of the fracturing pump under different driven modes was used as the load to obtain the internal stress state of the full-thread bolt and the double-headed bolt used in the fracturing operation site. Based on the stress state, the fatigue life of the two types of bolts under various loading conditions was then simulated using the Brown—Miller fatigue damage criterion. The results indicate that for bolts of the same structural type, the maximum stress and stress variation amplitude increase in the sequence of the diesel-driven, single-motor-driven, and dual-motor-driven methods. Additionally, under the same load, the stress of the full-thread bolt is lower than that of double-headed bolt. The fatigue life analysis results show that under the vibrational load of diesel drive, the full-thread bolt can obtain a longer fatigue life of approximately 2042.89 h. However, under the load of dual-motor-driven method, the fatigue life of double-headed bolt is the lowest, only 717.46 h. A comparison with the fatigue life of bolts in actual engineering projects indicates that the predicted fatigue life of the bolts is consistent with the actual service life, which can provide effective guidance for the inspection and maintenance of fracturing pump equipment.
Process Integration and Optimization of the Integrated Energy System Based on Coupled and Complementary “Solar-Thermal Power-Heat Storage”
Authors: Guo Lei , Zhang Di , Mi Jiahao , Li Pengyu , Liu Guilian
Published: January 2025

Within the context of “peak carbon and carbon neutrality”, reducing carbon emissions from coal-fired power plants and increasing the proportion of renewable energy in electricity generation have become critical issues in the transition to renewable energy. Based on the principles of cascaded energy utilization, this paper improves the coupling methodology of an integrated solar thermal and coal-fired power generation system based on existing research. A parabolic trough collector field and a three-tank molten salt thermal energy storage system are connected in series and then in parallel with the outlet of the reheater. ASPEN PLUS V14 and MATLAB R2018b software were used to simulate a steady-state model and numerical model, respectively, so as to study the feasibility of the improved complementary framework in enhancing the peak load capacity of coal-fired units and reducing their carbon emissions. Actual solar radiation data from a specific location in Inner Mongolia were gathered to train a neural network predictive model. Then, the peak-shaving performance of the complementary system in matching load demands under varying hours of thermal energy storage was simulated. The findings demonstrate that, under constant boiler load conditions, optimizing the complementary system with a thermal energy storage duration of 5 h and 50 min results in an energy utilization efficiency of 88.82%, accompanied by a daily reduction in coal consumption by 36.49 tonnes. This indicates that when operated under the improved coupling framework with optimal parameters, the peak regulation capabilities of coal-fired power units can be improved and carbon emission can be reduced.
Bioelectrical Impedance Analysis as a Helpful Tool in Pediatric Obesity Monitoring: A Case Report
Authors: Przytula Agata , Popiolek-Kalisz Joanna
Published: January 2025

Background and Clinical Significance: Childhood obesity and its associated complications are an emerging public health problem; thus, non-communicable chronic disease prevention should be implemented as early as possible. On the other hand, obesity management in children is a challenge in terms of achieving fat tissue reduction without any adverse outcomes on overall development. This is why close cooperation with young patients and their parents is crucial for success. Moreover, non-invasive but detailed monitoring guaranties insight in this process’s progress and safety. As obesity is a chronic disease with a tendency for recurrence, further follow-up should also be considered. Case Presentation: We present a case of a 10-year-old boy who was referred to a dietitian due to concerns about a diagnosis of obesity and metabolic complications including abnormal lipid profile and liver function. During the dietary consultation, body composition assessment with bioelectrical impedance analysis was conducted, which confirmed obesity. A detailed interview allowed for the identification of improper dietary patterns. The implemented lifestyle education and qualitative diet modifications led to fat mass reduction without any significant muscle loss after just one month. The metabolic profile was also improved. The patient remained under the care of a dietitian for the next 4 years with constant body composition monitoring, which enabled the relevant parties to address if body mass gain was a part of his normal development or if he suffered from obesity recurrence. The patient and his parents benefited from an individualized, patient-centered approach including dietary education, overall lifestyle modification, and detailed body composition monitoring. This way, the patient succeeded in fat content reduction with the constant assessment of the safety of this process. Moreover, the dietary education impacted the whole family’s lifestyle. Conclusions: This case emphasizes the role of body composition assessment in children. Obesity and metabolic complications resulting from an improper lifestyle can affect pediatric patients. Bioelectrical impedance analysis is a non-invasive tool that can improve the safety and effectiveness of nutritional interventions and could be included in routine pediatric obesity assessment.
Unmasking an Intracardiac Shunt in a Case of Persistent Unexplained Hypoxia: A Case Report
Authors: Sivalokanathan Sanjay , Saeedullah Usman , Locke Auston , Trivieri Maria Giovanna
Published: January 2025

Background and Clinical Significance: Pulmonary hypertension (PH) is characterized by an increase in mean pulmonary arterial pressure and pulmonary vascular resistance. It is frequently encountered in patients with significant intracardiac shunts, often necessitating the implementation of a closure device or surgical correction. Nevertheless, the occurrence of a concomitant atrial septal defect (ASD) with a right-to-left shunt inducing left ventricular dysfunction is a rare phenomenon. Case Presentation: A 69-year-old female patient with a history of heart failure (with preserved ejection fraction) and end-stage renal disease on hemodialysis presented to an outside facility, with syncope and hypoxia. She was recently diagnosed with severe pulmonary hypertension (measuring 86 mmHg). Right heart catheterization (RHC) revealed precapillary pulmonary hypertension (88/37/54 mmHg), prompting the initiation of intravenous epoprostenol. Nevertheless, the patient was persistently hypoxic, raising the possibility of a concomitant diagnosis. Upon review of the prior echocardiogram, which included a bubble study, an intracardiac shunt was identified. It was hypothesized that a combination of right ventricular failure and the right-to-left shunt resulting from the ASD contributed to the persistent hypoxemia. In light of this, prostacyclin therapy was continued alongside adjunctive vasopressors, resulting in clinical stabilization. The patient was eventually discharged with a treatment regimen that included subcutaneous Treprostinil. Conclusions: It is important to recognize that the consequences of PH are extensive, and that a rare yet significant etiology for persistent hypoxemia may be attributed to right-to-left shunting.
A Multilevel Surrogate Model-Based Precipitation Parameter Tuning Method for CAM5 Using Remote Sensing Data for Validation
Authors: Wu Xianwei , Hu Liang , Zheng Juepeng , Wang Lanning , Lu Haitian , Fu Haohuan
Published: January 2025

The uncertainty of physical parameters is a major factor contributing to poor precipitation simulation performance in Earth system models (ESMs), particularly in tropical and Pacific regions. To address the high computational cost of repetitive ESM runs, this study proposes a multilevel surrogate model-based parameter optimization framework and applies it to improve the precipitation performance of CAM5. A top-level surrogate model using gradient boosting regression trees (GBRTs) was constructed, leveraging the candidate point (CAND) approach applied to balance exploration and exploitation. A bottom-level surrogate model was then built based on a small, selected dataset; we designed a trust region approach to adjust the sampling region during the bottom-level tuning process. Experimental results demonstrate that the proposed method achieves fast convergence and significantly enhances precipitation simulation accuracy, with an average improvement of 19% in selected regions. In integrating optimization results through a nonuniform parameterization scheme and parameter smoothing, substantial improvements were observed in the South Pacific, Niño, South America, and East Asia. Comparisons with remote sensing data confirm that the optimized precipitation simulations do not introduce significant biases to other variables, validating the effectiveness and robustness of the proposed method.
Analyzing Travel and Emission Characteristics of Hazardous Material Transportation Trucks Using BeiDou Satellite Navigation System Data
Authors: Zou Yajie , Hu Qirui , Han Wanbing , Zhang Siyang , Chen Yubin
Published: January 2025

Road hazardous material transportation plays a critical role in road traffic management. Due to the dangerous nature of the cargo, hazardous material transportation trucks (HMTTs) have different route selection and driving characteristics compared to traditional freight trucks. These differences lead to unique travel and emission patterns, which in turn affect traffic management strategies and emission control measures. However, existing research predominantly focuses on safety aspects related to individual vehicle behavior, with limited exploration of the broader travel and emission characteristics of HMTTs. To bridge this gap, this study develops a comprehensive framework for analyzing the travel patterns and emissions of HMTTs. The methodology begins by applying a Gaussian mixture distribution model to identify vehicle stop points, eliminating biases associated with subjective settings. Origin–destination (OD) pairs are then determined through stop time clustering, followed by the extraction of travel characteristics using non-negative matrix factorization. Emissions are subsequently calculated based on the identified trip data. The relationship between emissions and land use characteristics is further analyzed using geographically weighted regression (GWR). Crucially, this study leverages data from the BeiDou Satellite Navigation System, focusing on HMTTs operating within Shanghai. The processed data reveal three distinct travel modes of HMTTs, categorized by spatiotemporal patterns: Daytime—Surrounding cities, Early morning—In-city, and Midnight—Scattered. Moreover, unlike other road vehicles, HMTT emissions are heavily influenced by industrial and company-related points of interest (POIs). These findings highlight the significant role of BeiDou Satellite Navigation System data in optimizing HMTT management strategies to reduce emissions and improve overall safety.