bluuebunny/crossref_metadata_2025 huggingface dataset:
Interrupted Coalescent Nitinol Clip versus Continuous Suture Coronary Anastomosis: A Comparative Endothelial Function Study
Authors: Demaria Roland G. , Fortier Simon , Malo Olivier , Carrier Michel , Perrault Louis P.
Published: March 2015

Background: A new penetrating stapled anastomotic system using nitinol microclips (Coalescent Surgical U-Clip) has been developed to facilitate the construction of compliant interrupted sutures for minimally invasive and robotic surgery as well as for conventional procedures. The purpose of this study was to determine the effect of nitinol U-Clips used for coronary anastomosis in the development of endothelial dysfunction, compared with conventional running sutures. Methods: In a porcine model, both internal thoracic arteries were harvested, and the heart was removed. In a Krebs solution, 2 anastomoses were realized ex vivo between internal thoracic arteries and the left anterior descending artery. One was carried out with 12 Coalescent microclips, and the other used conventional running 7-0 polypropylene suture material (Prolene). Coronary rings on the anastomotic sites were then placed in organ chambers filled with oxygenated Krebs solution. Vascular reactivity studies were performed in standard organ chamber experiments. After the contraction of the coronary arteries in response to prostaglandin F2a, the endothelium-dependent relaxation response to bradykinin was studied. The other coronary arteries served as controls. Results: There was no statistically significant difference among the groups (P > .05) in the amplitude of the contraction response to KCl and prostaglandin F2a. There were no statistically significant differences in endothelium-dependent relaxation response to bradykinin between the nitinol microclip group and controls, between the suture group and controls, and between the nitinol microclip and suture groups. Conclusions: Coalescent nitinol U-Clips used as anastomotic devices do not induce an endothelial dysfunction and allow a compliant anastomosis under satisfactory conditions.
New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans
Authors: Kim Hyun-Min , Colaiácovo Monica P
Published: March 2015

Although a growing number of studies have reported the importance of SUMOylation in genome maintenance and DNA double-strand break repair (DSBR), relevant target proteins and how this modification regulates their functions are yet to be clarified. Here, we analyzed SUMOylation of ZTF-8, the homolog of mammalian RHINO, to test the functional significance of this protein modification in the DSBR and DNA damage response (DDR) pathways in the Caenorhabditis elegans germline. We found that ZTF-8 is a direct target for SUMOylation in vivo and that its modification is required for DNA damage checkpoint induced apoptosis and DSBR. Non-SUMOylatable mutants of ZTF-8 mimic the phenotypes observed in ztf-8 null mutants, including reduced fertility, impaired DNA damage repair, and defective DNA damage checkpoint activation. However, while mutants for components acting in the SUMOylation pathway fail to properly localize ZTF-8, its localization is not altered in the ZTF-8 non-SUMOylatable mutants. Taken together, these data show that direct SUMOylation of ZTF-8 is required for its function in DSBR as well as DDR but not its localization. ZTF-8’s human ortholog is enriched in the germline, but its meiotic role as well as its post-translational modification has never been explored. Therefore, our discovery may assist in understanding the regulatory mechanism of this protein in DSBR and DDR in the germline.
An Rtf2 Domain-Containing Protein Influences Pre-mRNA Splicing and Is Essential for Embryonic Development in Arabidopsis thaliana
Authors: Sasaki Taku , Kanno Tatsuo , Liang Shih-Chieh , Chen Pao-Yang , Liao Wen-Wei , Lin Wen-Dar , Matzke Antonius J M , Matzke Marjori
Published: March 2015

Alternative splicing is prevalent in plants, but little is known about its regulation in the context of developmental and signaling pathways. We describe here a new factor that influences pre-messengerRNA (mRNA) splicing and is essential for embryonic development in Arabidopsis thaliana. This factor was retrieved in a genetic screen that identified mutants impaired in expression of an alternatively spliced GFP reporter gene. In addition to the known spliceosomal component PRP8, the screen recovered Arabidopsis RTF2 (AtRTF2), a previously uncharacterized, evolutionarily conserved protein containing a replication termination factor 2 (Rtf2) domain. A homozygous null mutation in AtRTF2 is embryo lethal, indicating that AtRTF2 is an essential protein. Quantitative RT-PCR demonstrated that impaired expression of GFP in atrtf2 and prp8 mutants is due to inefficient splicing of the GFP pre-mRNA. A genome-wide analysis using RNA sequencing indicated that 13–16% of total introns are retained to a significant degree in atrtf2 mutants. Considering these results and previous suggestions that Rtf2 represents an ubiquitin-related domain, we discuss the possible role of AtRTF2 in ubiquitin-based regulation of pre-mRNA splicing.
Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease
Authors: Qin Wenning , Dion Stephanie L , Kutny Peter M , Zhang Yingfan , Cheng Albert W , Jillette Nathaniel L , Malhotra Ankit , Geurts Aron M , Chen Yi-Guang , Wang Haoyi
Published: March 2015

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system is an adaptive immune system in bacteria and archaea that has recently been exploited for genome engineering. Mutant mice can be generated in one step through direct delivery of the CRISPR/Cas9 components into a mouse zygote. Although the technology is robust, delivery remains a bottleneck, as it involves manual injection of the components into the pronuclei or the cytoplasm of mouse zygotes, which is technically demanding and inherently low throughput. To overcome this limitation, we employed electroporation as a means to deliver the CRISPR/Cas9 components, including Cas9 messenger RNA, single-guide RNA, and donor oligonucleotide, into mouse zygotes and recovered live mice with targeted nonhomologous end joining and homology-directed repair mutations with high efficiency. Our results demonstrate that mice carrying CRISPR/Cas9-mediated targeted mutations can be obtained with high efficiency by zygote electroporation.
Further Results on Designs Arising from Some Certain Corona Graphs
Authors: Sumathi M.P. , Alwardi Anwar
Published: March 2015

In this paper, we determine the partially balanced incomplete block designs and association scheme which are formed by the minimum dominating sets of the graphs C3°K2, and C4°K2. Finally, we determine the number of minimum dominating sets of graph G = Cn°K2 and prove that the set of all minimum dominating sets of G = Cn°K2 forms a partially balanced incomplete block design with two association scheme.
Music Education As Part Of Estonian Basic School Students`Values Education
Authors: Kiilu Kristi , Muldma Maia
Published: March 2015

In today’s educational landscape of Estonia one of the priorities is values education, which is viewed as the main component in the development of students’ personality at school. Each educational activity immanently carries values, which, when recognised and purposefully implemented, may increase the effect of education in the desired area. With this study, the researchers are turning the spotlight on the opportunities for applying the potential effect of music in the process of the transfer from knowledge-based education to values-based education at Estonian schools. The objective is to ascertain the ways of expression of the effect of music education on the development of values in students of forms seven to nine. The study looked for the answers to the following questions: 1) What do students of the third stage of study of basic schools consider values and who has influence on them?; 2) What basis do music lessons provide for the development of students’ values?; 3) What music activities support the development of students’ values? Quantitative method was utilised to conduct the study. As the research instrument questionnaire was selected, which allowed involving a large number of respondents (n=243) and thus increase the reliability of study results. The results of this study confirm that through its learning activities music education gives diverse support to the formation and development of students’ values, because the emotional and communicative nature of music allows students to first of all get to know and thereafter develop themselves.
The Perception of Psychotherapy in Turkey
Authors: Coşan Deniz
Published: March 2015

This research explores the perception of psychotherapy in Turkey. The main aim of this study is to understand participants living in Turkey in relation to their views and experiences of psychotherapy, and to examine several aspects of the perception of psychotherapy in Turkey by using in-depth interviews with twenty participants. Some themes are highlighted by using the information gathered by interviews. These include: the family is very important in Turkish culture and so the family`s attitude affects people’s views and experiences; keeping family secrets hidden is valued, so telling them to a psychotherapist in order to solve them may not be a solution; the high cost of private psychotherapy in Turkey is the main factor affecting people’s attitudes towards it; state hospitals, in which psychotherapy services are free, may not be preferred because of negative beliefs about state workers and state hospitals. The data gathered may present some shared views of the Turkish people, however it is important to consider that, Turkey has a large population and a homogenous culture including many different languages, religions, sects, habits, views and life styles, so it is not possible to reflect all.
Reducing invasiveness of laparoscopic surgery using natural orifices and abdominal wall defects for extraction of the specimen
Authors: Lukovich Péter , Bokor Attila
Published: March 2015

Introduction: Due to significant technical evolution complex surgeries can be performed laparoscopically nowadays. However, laparotomy is needed frequently for the extraction of the specimen, which decreases the advantages of laparoscopy. Aim: The aim of the authors was to analyse and present their experience on the use of natural orifices and abdominal wall defects for extraction of the surgical specimen. Method: From 2009 the authors used natural orifices (stomach, vagina, rectum) when viscerotomy was an obligate part of laparoscopic surgery and, in a special gastrointestinal laparoscopic operation, the gate of the inguinal hernia for specimen extraction. Results: In 3 patients benign lesions of the stomach were extracted using gastroscope. In 6 patients with bowel endometriosis, in whom the wall of the vagina was completely infiltrated, the resected bowel was extracted transvaginally, and in 5 patients transrectal extraction of the specimen was performed. In 2 patients the inguinal hernia was used for the surgical specimen extraction after laparoscopic sigmoid resection, and in one patient a single-port was inserted into the gate of the hernia during laparoscopic cholecystectomy. Complications occurred only after transvaginal specimen extraction (rectovaginal fistula in 2 patients). Conclusions: Use of natural orifices and abdominal wall defects for surgical specimen extraction further decreases the invasiveness of laparoscopic surgery, if indications made appropriately. Orv. Hetil., 2015, 156(14), 552–557.
Thrombotic events and importance of IPSET thrombosis risk evaluation score in essential thrombocythaemia
Authors: Pósfai Éva , Marton Imelda , Nemes Attila , Borbényi Zita
Published: March 2015

Introduction: Thrombo-haemorrhagic complications contribute to both morbidity and mortality in patients with essential thrombocythaemia. Aim: The aim of the authors was to estimate the incidence of thrombotic events and to examine the clinical utility of IPSET thrombosis risk evaluation score against conventional two-categorical (low and high) risk assessment. Method: A retrospective analysis was carried out on 155 patients with essential thrombocythaemia (106 females; median age, 61 years) in a period between 1999 and 2014. Results: The analysis revealed 55 (35.5%) major thrombotic events before and 25 (16.1%) major thrombotic complications after establishment of the haematologic diagnosis. Significant differences were observed in thrombosis-free survival between the different IPSET groups (p = 0.002). Conclusions: The IPSET model was first examined in this cohort of patients with essential thrombocythaemia diagnosed in a single Hungarian haematologic centre. The results suggest that this score may provide more information than the conventional thrombosis risk assessment. Orv. Hetil., 2015, 156(14), 558–563.
Inventory of mammals in protected reserves and natural habitats of Tripura, northeast India with notes on existing threats and new records of Large Footed Mouse-eared Bat and Greater False Vampire Bat
Authors: Majumder Joydeb , Majumdar Koushik , Bhattacharjee Partha Pratim , Agarwala Basant Kumar
Published: March 2015

Twenty-four species representing 21 genera, 16 families and 7 orders of mammals were recorded in the Tripura state, northeast India, from an inventory done from 2006 to 2012. Ten of these species were found in wildlife sanctuaries as well as in primary forests. Four species were recorded exclusively from the wildlife sanctuaries and ten species were recorded only from primary forests. Order Primates was the most diverse group represented by 6 species from 4 genera in 3 families. Frequency sightings data showed that 11 species were rare, 2 species were occasional, one species was frequent, and another 10 species were common. Two species, Large-footed Mouse-eared Bat, Myotis sp., and Greater False Vampire Bat, Megaderma lyra, are new records from the study area.  Overall, 23 of the 24 species recorded are listed in the IUCN Red List, 14 species are listed in CITES, and 14 species are protected under the Indian Wildlife Protection Act, 1972. Threats being faced by many of the recorded mammals from human encroachments are highlighted.
Notes on rare clavarioid species (Fungi: Basidiomycota) in Patagonia, Argentina
Authors: Messuti María Inés , Lorenzo Laura Emma
Published: March 2015

The distributions of two clavarioid species, Clavulinopsis laeticolor (Berk. and M.A. Curtis) R.H. Petersen (Agaricales, Clavariaceae) and Lentaria rionegrensis R.H. Petersen (Gomphales, Lentariaceae), are extended and updated. Both species are poorly known in Argentina, and specifically in Patagonia; these species were cited only once in the 1960s and 1990s, respectively.
First reports of Bactrophora dominans Westwood, 1842 (Orthoptera: Romaleidae) from Venezuela and French Guiana (South America), with comments on biology, ecology and distribution of the species
Authors: González Jorge Manuel , Shea Jeff , Brewer-Carías Charles
Published: March 2015

New records of Bactrophora dominans Westwood, 1842 collected for the first time in Venezuela (Tepui Ichum), and French Guiana (Bélizon and Regina), are presented. Description of the insect, its colors, as well as ecological and biological notes and a historical overview of the known specimens in the genus and species are also included.
Formation of 17-18 yrs age girl students’ visual performance by means of visual training at stage of adaptation to learning loads
Authors: Bondarenko S.V. , Darzinska N.O. , Sіdilo L.V.
Published: March 2015

Purpose: substantiation of health related training influence of basketball and volleyball elements on functional state of 1 st year students’ visual analyzers in period of adaptation to learning loads with expressed visual component. Material: in experiment 29 students of 17-18 year age without visual pathologies participated. Indicators of visual performance were determined by correction table of Tagayeva and processed by Weston methodic. Accommodative function was tested by method of mechanical proximetry. Results: the authors worked out and tested two programs of visual training. Influence of visual trainings on visual performance’s main components (quickness, quality, integral indicators) was studied as well as eye’s accommodative function (by dynamic of position of the nearest point of clear vision). Conclusions: Application of visual trainings at physical education classes permits to improve indicators of visual analyzer’s performance as well as minimize negative influence of intensive learning loads on eye’ accommodative function.
New approaches to the organization of prestart preparation of qualified athletes in single combats (on an example of fencing)
Authors: Lopatenko G.O. , Kosik N.S. , Kosik N.L.
Published: March 2015

Purpose : to develop and investigate the effectiveness of complex extra-training means to enhance the prelaunch qualified athletes in fencing. Material : the study involved 12 qualified male fencers. Measurements were made of the latent period of simple and complex visual-motor response. Results: recommended set of proposed actions prelaunch 45 minutes before the start of the competition. The maximum stimulating effect of the experimental complex extra-training means in terms of neural properties of the organism is observed from the tenth to thirty minutes after the impact. Conclusions : We have reached the stimulatory effects of reduced overall duration of the workout to twenty minutes, allowing you to more efficiently organize the process of prelaunch qualified athletes in fencing as opposed to using traditional means.
Morphological functional and psychological indicators of 11-12 yrs age boys’ (members of preparatory special health groups of urban and countryside schools) development
Authors: Tamozhanskaya G.V.
Published: March 2015

Purpose: determination of anthropometrical and somatic indicators and factors of school anxiety of 11-12 yrs age boys - members of special health groups at urban and countryside schools. Material: in researches 50 boys of 11-12 years age participated. Results: the author determined difference between morphological-functional indicators and kinds of boys’ diseases. Besides, attendance of physical culture classes in respect to other subjects was analyzed. Comparative factors of children’s school anxiety were outlined. Schoolboys from countryside are more anxious about opinion of peers about themselves. Conclusions: boys’ morphological-functional indicators shall be considered as factor of determination and revelation of defects in harmonious development in system of physical education. Attention should be paid to different kinds of diseases and anxiety among boys of preparatory group.
Body weight satisfaction and disordered eating among youth who are active in sport in Singapore
Authors: Michael Chia , Marcus Lee
Published: March 2015

Purpose : The research examined the relationship between body weight satisfaction and disordered eating among youth who are active in sport in Singapore. Method : 137 youths (82 boys and 55 girls; age 12-13) enrolled in school sport completed two self-report questionnaires- SCOFF for disordered eating and body weight satisfaction- on two separate occasions that were six months apart (T1 vs. T2). Results : Body mass index for age classifications revealed that 5.1% were severely underweight; 1.5% underweight; 88.3% acceptable weight; 4.4% overweight and 0.7% were severely overweight. Conclusions : (i) the prevalence of disordered eating was 46% at baseline measurement and this remained stable at 45.3% six months later; (ii) there was no sex difference for disordered eating on the two measurement occasions (T1 vs. T2, p>0.05); (iii) the prevalence of youths unsure of their bodyweight satisfaction was 26.6-21.2% which compared to 88.3% adjudged to be of healthy weight; across T1 and T2, more male subjects wanted to gain bodyweight while more female subjects wanted to lose bodyweight; and (iv) subjects who were dissatisfied with their bodyweight had significantly greater odds of being at risk for developing DE. Holistic education programmes based upon body image and nutrition, are recommended.
O PAPEL DA VERDADE NA TEORIA DA RACIONALIDADE DE THOMAS KUHN
Authors: Silva Adan John Gomes da
Published: March 2015

O trabalho tem como objetivo investigar a relação existente entre as ideias de Thomas Kuhn acerca da racionalidade científica e aquelas que dizem respeito à relação entre ciência e realidade. Nesse sentido, coloca o antirrealismo deste autor como um elemento essencial da teoria da racionalidade desenvolvida ao longo de sua obra, relação que deve ser corroborada ao explicar como esse antirrealismo é antes um pressuposto dessa teoria da racionalidade do que uma implicação necessária das observações históricas de Kuhn. No fim, o trabalho espera deixar claro que qualquer leitura desse autor que separe essas duas dimensões de sua obra correrá o risco de ignorar a profundidade de seu pensamento.
AS TECNOLOGIAS DIGITAIS NA EDUCAÇÃO À LUZ DA QUESTÃO DA TÉCNICA EM HEIDEGGER
Authors: Cambraia Adão Caron , Fensterseifer Paulo Evaldo
Published: March 2015

O artigo apresenta alguns aspectos acerca da questão da técnica em Heidegger e faz um exercício de aproximação com as tecnologias digitais na educação. Essa reflexão objetiva fazer uma atualização do pensamento do filósofo, que demonstra uma crescente necessidade de domínio e usos sem reflexão da tecnologia na vida e nas escolas. Foi elaborado a partir de Heidegger e Arendt e da pesquisa bibliográfica de autores como: Shery Turkle, Giovanni Sartori e Francisco Rudiger. Apontamos para a necessidade de questionar a técnica para chegarmos a essência da técnica e construirmos um caminho de liberdade do pensamento, ou seja, uma outra relação com esse fenômeno.
O SERTANEJO: CAMINHOS E (DES) CAMINHOS DA LIBERTAÇÃO
Authors: Miranda Angela Luzia , Souza Leonardo Da Rocha Bezerra de
Published: March 2015

Ao longo do Século XX, ocorreram diversas mudanças no cenário geopolítico e cultural brasileiro, em especial na região nordeste, onde o fluxo de migrantes para a região sudeste do Brasil (SP, MG, RJ) provocou grandes transformações na vida do nordestino, trabalhador do campo, também chamado de “sertanejo”, do ponto de vista da sua identidade cultural. A identificação deste processo está evidenciada na obra do cantor e compositor Luiz Gonzaga (1912 – 1989), que retratou as muitas fases e faces dessas transformações, demonstrando, através da música, os impactos sofridos pelos sertanejos, do ponto de vista da sua cultura. Este trabalho propõe analisar, através da obra de Luiz Gonzaga, o confronto do sertanejo em termos de cultura e identidade, com o novo cenário em que foi submetido, involuntariamente, através do processo migratório para as regiões mais industrializada do país. Analisaremos estes recortes através das categorias da Filosofia da Libertação, como: Alienação, Totalidade e, sobretudo, através da categoria de Exterioridade, presentes na obra do filósofo argentino Enrique Dussel.
DO MATERIAL AO ESPIRITUAL: UMA LEITURA DA “CHAMA” A PARTIR DE WALTER BENJAMIN ENTRE “PONTOS NODAIS” E “FARNEL” DO ARTISTA ARTUR SOUZA
Authors: Marinho Clayton Rodrigo da Fonsêca , Kangussu Imaculada Maria Guimarães
Published: March 2015

A proposta de trabalho é realizar uma leitura da passagem entre as obras da exposição “Pontos Nodais” e “Farnel” do artista Artur Souza, tendo como condutor da leitura a ideia de “chama” a partir do filósofo judeu-alemão Walter Benjamin. Tencionando a busca de um “teor coisal” e “teor de verdade”, a filosofia parece vacilar em tentar apreender essa chama alquímica e não necessariamente os elementos que a compõe.
RAZÃO E MORAL EM KANT
Authors: Bezerra Hildemar De Araújo
Published: March 2015

Sob a ótica da Filosofia Moral de Kant, esse texto tem como objetivo responder (ou refletir sobre) a seguinte pergunta: por que devemos ser morais? Trata-se de apresentar a Moral como uma exigência da faculdade prática da razão e como fazendo parte da natureza humana. Neste sentido, como se verá, agir moralmente é agir de acordo com nossa natureza racional. Tendo em vista isso, o esforço filosófico kantiano será o de mostrar como a moralidade é derivada da razão, se apresentando como uma obrigação ou um DEVER para todo ser dotado de razão, ou pelo menos, àqueles que ajam de acordo com sua natureza racional.
CIÊNCIA E MATEMÁTICA, NA REPÚBLICA, DE PLATÃO
Authors: Araújo Hugo Filgueiras de
Published: March 2015

O presente trabalho tem o intuito de entender como Platão na República aborda os conceitos de matemática e ciência, mais especificamente nos livros V, VI e VII desse diálogo. Primeiramente foram levantadas algumas questões consideradas preliminares em relação ao modo peculiar com o qual Platão desenvolveu sua escrita, no caso o estilo dialógico que pede todo um cuidado em sua leitura, como também levantou-se a problemática das traduções feitas do grego para o português que, por vezes, dificulta seu entendimento. Em um segundo momento foi abordado o entendimento do termo ciência nos gregos, fazendo uma relação com a matemática. Como ponto de partida, foi tomado o pressuposto de que para Platão a matemática não se enquadra na classificação de ciência. Busca-se nessa pesquisa entender estes conceitos na filosofia platônica, e não há como realizar tal propósito sem lançar mão das questões que mais são relevantes na filosofia platônica (epistemologia e ontologia), tomando mão dos argumentos da Reminiscência e da Teoria das Formas. O trabalho termina por concluir que ciência só é considerada na filosofia platônica aquela que pode ter o conhecimento da realidade, e essa, segundo o filósofo, é a dialética; ficando a matemática, por conseguinte, enquadrada dentro de um âmbito do conhecimento que Platão na República diz estar entre a opinião (doxa) e a própria ciência (epistême) que é o entendimento (dianóia).
QU’EST-CE QU’UN SAVOIR POPULAIRE ? TRANSMISSION POPULAIRE SAVANTE DES SAVOIRS NON ECRITS
Authors: Mokaddem Salim
Published: March 2015

Os problemas relacionados à educação e à transmissão são muito frequentemente confrontados com os do registro e da memória escrita; a patrimonialização dos saberes ainda passa, majoritariamente, pelas vias clássicas da alfabetização, do discurso escrito e dos sistemas acadêmicos (currículos, diplomações, concursos, cartas de motivação, avaliações etc). No entanto, os saberes orais e as práticas não-discursivas – no sentido da oralidade da transmissão – são tão formativas e transmissoras quanto os saberes e as verdades formais normalizadas por processos dos quais Foucault analisou as ordens e as lógicas específicas de inclusão, de exclusão, de ordem e de produção. Nós gostaríamos de introduzir um corpo de reflexão a partir de uma história heteromórfica em relação àquela que a Universidade continua e santifica pela consagração dos saberes escritos, homologados e reconhecidos nas validações, o corpus que ela ritualiza, a forma institucional que ela impõe, os textos que ela produz, autoriza, proíbe ou canoniza, muitas vezes recorrendo a tipos de soberanias ou reconhecimentos legítimos, rejeitando justamente o que não está sob seu próprio poder.
EXPERIÊNCIA AMOROSA ON-LINE E NARRATIVA
Authors: Silva Vergas Vitória Andrade da
Published: March 2015

O artigo se propõe a estudar, segundo o olhar da filosofia contemporânea, o fenômeno do namoro virtual através da observação do Orkut, rede social on-line. Para tanto, analisa os debates travados em fóruns e enquetes de uma de suas comunidades virtuais, chamada Conheci meu amor pela internet. A análise empírica demonstra que esses fóruns e enquetes apresentam-se enquanto um fenômeno social que dá origem a uma forma particular de apresentação do eu na internet. No ensejo por apresentarem-se, os mesmos atores acabam por construir narrativas de si. O que se observa nessas narrativas de namoros virtuais é a predominância de uma intriga, cujo desfecho revela-se exitoso, de resultado satisfatório, feliz. Os narradores elegem casos de namoros virtuais que se desenrolam sob a forma de uma felicidade amorosa associada a ideais românticos como dignos de serem retratados. O teor dessas narrativas é desses aspectos tributário. Portanto, a partir dessas formulações, defende-se neste trabalho a tese segundo a qual as narrativas de namoros virtuais são um misto de fato e ficção, na medida em que são narrativas tecidas com empréstimo tanto do imaginário romântico quanto da própria experiência amorosa vivida nos namoros. Em resumo, esta pesquisa esforça-se por compreender fóruns e enquetes cujo cotidiano amoroso é ficcionalizado e dramatizado através de jogos performáticos compostos pela fabulação romântica e pela experiência de concretude dos namoros virtuais.
Editorial
Authors: Lima Jorge Dos Santos
Published: March 2015

A DIALEKTIKÉ é um periódico de Filosofia do Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte (IFRN). Esta edição tematiza, entre outros, os seguintes pensadores:  Dretske, Enrique Dussel, Foucault, Heidegger, Kant, Paul Ricoeur, Platão, Thomas Kuhn e Walter Benjamin. Neste volume (Vol. 1, 2014), além de autores do IFRN, há contribuições advindas de diversas instituições como o Instituto Federal de Educação, Ciência e Tecnologia Farroupilha, a Universidade Regional do Noroeste do Estado do Rio Grande do Sul, a Escola de Ciências e Tecnologias da Universidade Federal do Rio Grande do Norte, a Universidade Federal de Ouro Preto (UFOP), a Universidade Federal do Ceará e uma instituição estrangeira, a Université Montpellier 2/França. Desse modo, agradecemos a confiança dos autores e a colaboração dos avaliadores ad hoc e convidamos a todos vocês, pesquisadores ou não, a apreciarem nossa primeira edição com a leitura dos textos aqui publicados.
Bedeutung der Biotechnologie beim Rind in Europa
Authors: Stinshoff H. , Wrenzycki C.
Published: March 2015

Die Biotechnologie in der Reproduktionsmedizin bietet vielfältige Anwendungsbereiche und beinhaltet ein hohes Innovationspotenzial bei Nutztieren. Angesichts der globalen Entwicklungen können die neuen Erkenntnisse und Techniken wichtige Hilfsmittel sein, um zukünftigen Herausforderungen besser begegnen zu können. So kann der Einsatz biotechnologischer Verfahren im Bereich der Tierproduktion die Versorgung der Bevölkerung mit ausreichenden Mengen qualitativ hochwertiger Nahrungsmittel gewährleisten. Tiergenetische Ressourcen lassen sich durch die Anlage von Sperma- und Embryonenbanken erhalten. Durch die frühzeitige Diagnose von Erbfehlern, die Erzeugung von Nachkommen mit vorherbestimmtem Geschlecht und die Vermeidung von Zuchttiertransporten durch die Versendung tiefgefrorener Embryonen kommt es zu einer Verbesserung des Tierschutzes. Eine besondere Anwendungsmöglichkeit bietet sich außerdem durch den Einsatz speziesübergreifender Modelle, die auch für die assistierten Reproduktionstechniken in der Humanmedizin eine wichtige Rolle spielen. Daraus resultiert nicht nur in Deutschland ein erhöhter Bedarf in der Nutzung der biotechnologischen Verfahren und deren Weiterentwicklung durch die Förderung von Forschungsprojekten.
Short-term Response of Holcus lanatus L. (Common Velvetgrass) to Chemical and Manual Control at Yosemite National Park, USA
Authors: Jones Laura J. , Ostoja Steven M. , Brooks Matthew L. , Hutten Martin
Published: March 2015

One of the highest priority invasive species at both Yosemite and Sequoia and Kings Canyon national parks is Holcus lanatus L. (common velvetgrass), a perennial bunchgrass that invades mid-elevation montane meadows. Despite velvetgrass being a high priority species, there is little information available on control techniques. The goal of this project was to evaluate the short-term response of a single application of common chemical and manual velvetgrass control techniques. The study was conducted at three montane sites in Yosemite National Park. Glyphosate spot-spray treatments were applied at 0.5, 1.0, 1.5, and 2.0% concentrations, and compared with hand pulling to evaluate effects on cover of common velvetgrass, cover of other plant species, and community species richness. Posttreatment year 1 cover of common velvetgrass was 12.1% ± 1.6 in control plots, 6.3% ± 1.5 averaged over the four chemical treatments (all chemical treatments performed similarly), and 13.6% ± 1.7 for handpulled plots. This represents an approximately 50% reduction in common velvetgrass cover in chemically- treated plots recoded posttreatment year 1 and no statistically significant reduction in hand pulled plots compared with controls. However, there was no treatment effect in posttreatment year 2, and all herbicide application rates performed similarly. In addition, there were no significant treatment effects on nontarget species or species richness. These results suggest that for this level of infestation and habitat type, (1) one year of hand pulling is not an effective control method and (2) glyphosate provides some level of control in the short-term without impact to nontarget plant species, but the effect is temporary as a single year of glyphosate treatment is ineffective over a two-year period.
«GREEN» STANDARDS AND «GREEN» BUILDING DEVELOPMENT
Authors: LEKAREVA N. A
Published: March 2015

The article is devoted to burning theme for contemporary architecture and city-building, concerned the high-technological approach to architectural projecting, taking into account the requirements of ecology, energy-efficiency and the increase of building quality with minimum expenses and maximum comfort. The national standards of green building are meant to adapt international requirements for development of energy-efficient, ecological and comfortable building or complex to local conditions. The examples of ecological and high-technological approach in russian and foreign projecting practice are presented.
SOCIAL ADDRESS OF THE DESIGN OF RESIDENTIAL AND MIXED RESIDENTIAL GROUP WITH CONSIDERATION OF THE NEEDS OF THE COMMUNITY
Authors: ZhOGOLEVA A. V
Published: March 2015

The decision of the socially-focused problems of residential group design is directed to the creation of residential group environment, as the steady socially-spatial complex, promoting formation of the neighbourhood. This article explores the architectural- planning characteristics of residential group, associated with the needs of neighbours community, such as functional and planning organization of territory, differentiation of territory on ownership and control, design of heterogeneous socio-cultural living environment, etc.
Immediately Sequential Bilateral Cataract Surgery—A Global Perspective
Authors: Arshinoff Steve A ,   Directing Partner, York Finch Eye Associates, Humber River Hospital, Toronto, Ontario, Canada; Assistant Professor, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Assistant Clinical Professor, Surgery (Adjunct), McMaster University, Hamilton, 2115 Finch Ave W #316, Toronto, Ontario, Canada M3N 2V6. E: ifix32is@gmail.com
Published: March 2015

By the mid 1990s, the evolution of progressively safe and predictable cataract surgery saw the resurgence of centuries of interest in performing immediately sequential bilateral cataract surgery (ISBCS). Within 10 years ISBCS had become generally accepted and the International Society of Bilateral Cataract Surgeons (iSBCS) was formed (September 2008) to “promote education, mutual cooperation, and progress in simultaneous bilateral cataract surgery.” The first initiative of the society members was to create a document “iSBCS General Principles for Excellence in ISBCS 2009,” which was intended to disseminate information about the best practices they had discovered to assist novice ISBCS surgeons. Next, ISBCS needed to be studied. Soon, data began to clarify some advantages of ISBCS, and risks were carefully evaluated. It soon became apparent that the main impediment to the performance of ISBCS, globally, was money, in that many jurisdictions financially penalized surgeons who performed ISBCS. Presently, we know that ISBCS carries many benefits to the patient, his/her family, the surgical facility, and society. The feared risks for simultaneous bilateral endophthalmitis, the requirement to adjust intraocular lens (IOL) selection for second eyes, based on first eye results, and others, have simply not been borne out under scrutiny. ISBCS is now rapidly increasing in its performance and acceptance globally, but the financial factors remain to be solved.
Comparison of Contact Lens and Intraocular Lens Correction of Monocular Aphakia During Infancy
Authors: Weil Natalie , Lambert Scott R ,   Pediatric Ophthalmology Fellow,   R Howard Dobbs Professor of Ophthalmology and Pediatrics, Emory University, Atlanta, Georgia, US. E: scott.lambert@emory.edu
Published: March 2015

The Infant Aphakia Treatment Study recommended primary intraocular lens (IOL) implantation be reserved for infants with parents unable to manage contact lenses. The best baseline predictor of a good visual outcome was private health insurance. IOL implantation was associated with more adverse events, but lower direct costs to parents.
Small Incision Lenticule Extraction (SMILE) in 2015
Authors: Reinstein Dan Z ,   Medical Director, London Vision Clinic, 138 Harley Street, London W1G 7LA, UK. E: dzr@londonvisionclinic.com; Clinical Professor of Ophthalmology, Department of Ophthalmology, Columbia University Medical Center, New York, NY, US; Clinical Professor of Ophthalmology, Centre Hospitalier National d’Ophtalmologie, Paris, France
Published: March 2015

Following the early work by Sekundo et al. and Shah et al., small incision lenticule extraction (SMILE) using the VisuMax femtosecond laser (Carl Zeiss Meditec) has become increasingly popular. The accuracy of the lenticule dimensions has been verified using very-high-frequency digital ultrasound and optical coherence tomography. Visual and refractive outcomes and safety have been shown to be similar to LASIK. A number of studies have demonstrated a lower reduction and faster recovery of corneal sensitivity and subbasal nerve fiber density after SMILE than LASIK, as expected since the anterior stroma is disturbed only by the small incision. The potential biomechanical advantages of SMILE have been modeled based on the nonlinearity of tensile strength through the stroma. Extraction of an intact lenticule has also given rise to new applications such as cryopreservation of the lenticule for later reimplantation, and a new procedure, endokeratophakia, in which a myopic SMILE lenticule is implanted into a hyperopic patient.
Toward Safer Treatment Options for Advanced Keratoconus
Authors: Parker Jack , Konder Ricarda M , van Dijk Korine , Melles Gerrit RJ ,   Ophthalmology Resident; Ophthalmology Resident, UAB Callahan Eye Hospital, Birmingham, Alabama, US,   Research Fellow,   Optometrist; Melles Cornea Clinic, Rotterdam, The Netherlands,   Director, Netherlands Institute for Innovative Ocular Surgery, Rotterdam, The Netherlands. E: research@niios.com; Melles Cornea Clinic, Rotterdam, The Netherlands; Amnitrans EyeBank Rotterdam, The Netherlands
Published: March 2015

Keratoconus is a bilateral and progressive corneal disease characterized by a significant increase in irregular astigmatism and corneal thinning. Numerous treatments—including penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK), ultraviolet-crosslinking (UV-CXL), and intracorneal ring segments—are available for halting progression and/or obtaining (partial) visual rehabilitation. Recently, midstromal Bowman layer transplantation has been introduced as a new treatment option for advanced keratoconus. This technique has shown significant promise in halting disease progression and postponing riskier procedures such as PK or DALK.
When Should We Perform Incisional Glaucoma Surgery?
Authors: Vinod Kateki , Panarelli Joseph F ,   Ophthalmologist, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th Street, New York, NY 10003, US. E: jpanarelli@nyee.edu,   Assistant Professor of Ophthalmology, Icahn School of Medicine, Mount Sinai; Associate Residency Program Director, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, US
Published: March 2015

Deciding when to perform glaucoma surgery can be challenging despite evidence in the literature supporting its safety and efficacy. In addition to clinical examination, visual field testing, and optic nerve imaging, other patient factors such as age, family history, and ocular comorbidities influence the decision-making process and are especially helpful in patients with borderline intraocular pressure and/or equivocal progression. The potential for a complicated postoperative course and lack of immediate visual benefit makes glaucoma surgery less straightforward than other ophthalmic procedures. The decision to operate is ultimately based on a discussion between each individual patient and the glaucoma surgeon, with careful consideration of disease severity, risk for progression, and quality of life.
Development of a Stem Cell Therapy for Glaucoma
Authors: Doorenbos Marianne , Shi-Jiang Lu , Chen Dong Feng ,   Medical Student, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands,   Senior Director of Research, Ocata Therapeutics, Marlborough, Massachusetts, US,   Associate Professor of Opthalmology, Schepens Eye Research Institute, Massachusetts Ear and Eye, Department of Ophthalmology, Harvard Medical School, 20 Staniford Street, Boston, MA 2114, US. E: dongfeng_chen@meei.harvard.edu
Published: March 2015

Glaucoma is the most common form of optic neuropathy and a major cause of blindness worldwide. Currently, there is no cure for glaucoma. Damage to retinal ganglion cells and optic nerve caused by the diseases is permanent. Stem cells, which can divide indefinitely and differentiate into various cell types, offer a great premise for cell-replacement therapy. Recent breakthroughs in stem cell research that enable generation of pluripotent stem cells from adult somatic cells by reprogramming technology have opened new therapeutic possibilities. However, besides the common factors in inducing directed and homogenous cell differentiation and integration into the host tissue and establishing functionality, stem cell therapy for glaucoma is especially challenged by difficulties in driving optic nerve regeneration or repair. On the contrary, stem cell transplantation may still gain functional benefits by secreting neurotrophic factors and promoting neural plasticity. This review will discuss these advances and challenges in stem cell therapy.
Recent Advances in Topical Therapeutics for Vitreoretinal Diseases
Authors: Gibson Jonathan M , McGinnigle Samantha ,   Professor of Ophthalmology; Department of Optometry, Vision Sciences Building, Aston University, Birmingham, B4 7ET, UK. E: j.m.gibson@aston.ac.uk,   Optometrist, School of Life and Health Sciences, Aston University, Birmingham, UK
Published: March 2015

Eye drops are convenient for patients, but achieving therapeutic doses and maintaining sustained drug release without frequent re-application to treat diseases of the retina has been largely unsuccessful. Topical administration of drugs is hindered by the anatomy, physiology, and biochemistry of the eye and its highly effective defence mechanisms. Advances in nanotechnology have led to the experimental use of topical permeation-enhancing liposomes, emulsions, and microspheres to enhance absorption and penetration of drugs across membranes; allow controlled release of the drug; and to target drugs at distinct tissues to allow sufficient local bioavailability. In the near future it is hoped that improved technologies may provide means of sustained topical drug delivery for retinal therapy, with improved side-effect profiles and reduced cost compared with currently available clinical treatments.
New Technologies for the Developing World
Authors: Feldman Brad H ,   Ophthalmologist, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, US. E: bradhfeldman@gmail.com
Published: March 2015

Ophthalmic innovation is nearly always driven by wealthy nations, and poorer populations with higher rates of blindness are rarely the targets or recipients of such advances. A symposium at the 2014 American Academy of Ophthalmology’s annual meeting addressed this mismatch of innovation and need by looking at the various approaches being taken to create solutions specifically aimed at the developing world.
β2‐Glycoprotein I‐Dependent Anti‐Cardiolipin Antibodies Associated With Periodontitis in Patients With Systemic Lupus Erythematosus
Authors: Wang Chen‐Ying , Chyuan I‐Tsu , Wang Ya‐Li , Kuo Mark Yen‐Ping , Chang Ching‐Wen , Wu King‐Jean , Hsu Ping‐Ning , Nagasawa Toshiyuki , Wara‐aswapati Nawarat , Chen Yi‐Wen
Published: March 2015

Background: It was reported that patients with systemic lupus erythematosus (SLE) exhibited increased levels of anticardiolipin (anti‐CL) antibodies, a class of antiphospholipid antibodies associated with thrombosis. β2‐glycoprotein I (β2GPI) has been considered as the actual target antigen for anti‐CL antibodies. This study investigates the association of periodontal infection with anti‐CL antibodies in patients with SLE.

Methods: Fifty‐three SLE female patients and 56 healthy female volunteers were recruited in this case‐control study. All participants received periodontal examinations. The presence of Porphyromonas gingivalis and Treponema denticola in saliva and plaque samples was detected by polymerase chain reaction. Levels of serum anti‐CL and anti‐β2GPI antibodies were examined using enzyme‐linked immunosorbent assay.

Results: Patients with SLE exhibited more periodontal attachment loss and increased titers of serum anti‐CL and anti‐β2GPI antibodies compared with healthy controls. Patients with active SLE who harbored P. gingivalis or P. gingivalis together with T. denticola intraorally exhibited significantly higher anti‐CL and anti‐β2GPI antibodies than those without these bacteria. Anti‐CL and anti‐β2GPI antibody levels correlated positively with clinical attachment level. Furthermore, increased anti‐β2GPI antibody levels were significantly associated with C‐reactive protein and erythrocyte sedimentation rate.

Conclusions: Elevated anti‐CL and anti‐β2GPI antibody levels were associated with periodontopathic bacteria and periodontal breakdown in patients with SLE. Periodontitis might be a modifiable risk factor for SLE.
Black Barley as a Means of Mitigating Deoxynivalenol Contamination
Authors: Choo Thin Meiw , Vigier Bernard , Savard Marc E. , Blackwell Barbara , Martin Richard , Wang Junmei , Yang Jianming , Abdel‐Aal El‐Sayed M.
Published: March 2015

Fusarium head blight (FHB) is a destructive disease of barley (Hordeum vulgare L.) in many countries. The disease can result in mycotoxin contamination such as deoxynivalenol (DON) in the grain. The objective of this study was to determine if black barley is more resistant to DON accumulation than yellow barley as the former contains a high level of phenolic compounds. In one experiment, 100 recombinant inbred lines (RILs) were derived from each of the two barley crosses: AC Klinck/CH9403‐2 and AC Legend/CH9403‐2 with half of them being black and the other half yellow. These lines along with their parents were evaluated for resistance to DON accumulation under natural infection conditions at Harrington (Prince Edward Island) for 3 yr (2005–2007). They were also evaluated for resistance to FHB incidence and DON accumulation under artificial inoculation conditions at Ottawa (Ontario) in 2005 and 2006 and at Hangzhou (China) in 2005–2006. Black RILs on average contained 17 to 59% less DON than yellow RILs under natural conditions in both crosses in two tests. Black RILs had 2 to 20% lower FHB incidence than yellow RILs in both crosses in two tests and contained 16 to 18% less DON in one test. In another experiment, 26 hulless accessions were evaluated at Ottawa in 2011 and 2012. Black accessions on average contained 53% less DON than the yellow accessions in 2012 and they contained 46% less DON when the DON data were combined over 2 yr. In conclusion, black barley can be used as a means of mitigating DON contamination.