bluuebunny/crossref_metadata_2025 huggingface dataset:
Matrix stiffness regulates microvesicle-induced fibroblast activation
Authors: Schwager Samantha C. , Bordeleau Francois , Zhang Jian , Antonyak Marc A. , Cerione Richard A. , Reinhart-King Cynthia A.
Published: April 2019

Extracellular vesicles released by cancer cells have recently been implicated in the differentiation of stromal cells to their activated, cancer-supporting states. Microvesicles, a subset of extracellular vesicles released from the plasma membrane of cancer cells, contain biologically active cargo, including DNA, mRNA, and miRNA, which are transferred to recipient cells and induce a phenotypic change in behavior. While it is known that microvesicles can alter recipient cell phenotype, little is known about how the physical properties of the tumor microenvironment affect fibroblast response to microvesicles. Here, we utilized cancer cell-derived microvesicles and synthetic substrates designed to mimic the stiffness of the tumor and tumor stroma to investigate the effects of microvesicles on fibroblast phenotype as a function of the mechanical properties of the microenvironment. We show that microvesicles released by highly malignant breast cancer cells cause an increase in fibroblast spreading, α-smooth muscle actin expression, proliferation, cell-generated traction force, and collagen gel compaction. Notably, our data indicate that these phenotypic changes occur only on stiff matrices mimicking the stiffness of the tumor periphery and are dependent on the cell type from which the microvesicles are shed. Overall, these results show that the effects of cancer cell-derived microvesicles on fibroblast activation are regulated by the physical properties of the microenvironment, and these data suggest that microvesicles may have a more robust effect on fibroblasts located at the tumor periphery to influence cancer progression.
Acyloxyacyl hydrolase modulates depressive-like behaviors through aryl hydrocarbon receptor
Authors: Aguiniga Lizath M. , Yang Wenbin , Yaggie Ryan E. , Schaeffer Anthony J. , Klumpp David J. ,   MAPP Research Network Study Group
Published: April 2019

Corticotropin-releasing factor (CRF) regulates stress responses, and aberrant CRF signals are associated with depressive disorders. Crf expression is responsive to arachidonic acid (AA), where CRF is released from the hypothalamic paraventricular nucleus (PVN) to initiate the hypothalamic-pituitary-adrenal axis, culminating in glucocorticoid stress hormone release. Despite this biological and clinical significance, Crf regulation is unclear. Here, we report that acyloxyacyl hydrolase, encoded by Aoah, is expressed in the PVN, and Aoah regulates Crf through the aryl hydrocarbon receptor (AhR). We previously showed that AOAH-deficient mice mimicked interstitial cystitis/bladder pain syndrome, a condition frequently associated with comorbid anxiety and depression. With the use of novelty-suppressed feeding and sucrose preference assays to quantify rodent correlates of anxiety/depression, AOAH-deficient mice exhibited depressive behaviors. AOAH-deficient mice also had increased CNS AA, increased Crf expression in the PVN, and elevated serum corticosterone, consistent with dysfunction of the hypothalamic-pituitary-adrenal axis. The human Crf promoter has putative binding sites for AhR and peroxisome proliferator-activated receptor (PPARγ). PPARγ did not affect AA-dependent Crf expression in vitro, and conditional Pparγ knockout did not alter the AOAH-deficient depressive phenotype, despite previous studies implicating PPARγ as a therapeutic target for depression. In contrast, Crf induction was mediated by AhR binding sites in vitro and increased by AhR overexpression. Furthermore, conditional Ahr knockout rescued the depressive phenotype of AOAH-deficient mice. Finally, an AhR antagonist rescued the AOAH-deficient depressive phenotype. Together, our results demonstrate that Aoah is a novel genetic regulator of Crf mediated through AhR, and AhR is a therapeutic target for depression.
Aging changes in protective balance and startle responses to sudden drop perturbations
Authors: Sanders Ozell , Hsiao Hao Yuan , Savin Douglas N. , Creath Robert A. , Rogers Mark W.
Published: April 2019

This study investigated aging changes in protective balance and startle responses to sudden drop perturbations and their effect on landing impact forces (vertical ground reaction forces, vGRF) and balance stability. Twelve healthy older (6 men; mean age = 72.5 ± 2.32 yr, mean ± SE) and 12 younger adults (7 men; mean age = 28.09 ± 1.03 yr) stood atop a moveable platform and received externally triggered drop perturbations of the support surface. Electromyographic activity was recorded bilaterally over the sternocleidomastoid (SCM), middle deltoid, biceps brachii, vastus lateralis (VL), biceps femoris (BF), medial gastrocnemius (MG), and tibialis anterior (TA). Whole body kinematics were recorded with motion analysis. Stability in the anteroposterior direction was quantified using the margin of stability (MoS). Incidence of early onset of bilateral SCM activation within 120 ms after drop onset was present during the first-trial response (FTR) for all participants. Co-contraction indexes during FTRs between VL and BF as well as TA and MG were significantly greater in the older group (VL/BF by 26%, P < 0.05; TA/MG by 37%, P < 0.05). Reduced shoulder abduction between FTR and last-trial responses, indicative of habituation, was present across both groups. Significant age-related differences in landing strategy were present between groups, because older adults had greater trunk flexion ( P < 0.05) and less knee flexion ( P < 0.05) that resulted in greater peak vGRFs and decreased MoS compared with younger adults. These findings suggest age-associated abnormalities of delayed, exaggerated, and poorly habituated startle/postural FTRs are linked with greater landing impact force and diminished balance stabilization.

NEW & NOTEWORTHY This study investigated the role of startle as a pathophysiological mechanism contributing to balance impairment in aging. We measured neuromotor responses as younger and older adults stood on a platform that dropped unexpectedly. Group differences in landing strategies indicated age-associated abnormalities of delayed, exaggerated, and poorly habituated startle/postural responses linked with a higher magnitude of impact force and decreased balance stabilization. The findings have implications for determining mechanisms contributing to falls and related injuries.
Oscillating Cosmological Solutions in the Modified Theory of Induced Gravity
Authors: Zaripov Farkhat
Published: April 2019

This work is the extension of author’s research, where the modified theory of induced gravity (MTIG) is proposed. In the framework of the MTIG, the mechanism of phase transitions and the description of multiphase behavior of the cosmological scenario are proposed. The theory describes two systems (stages): Einstein (ES) and “restructuring” (RS). This process resembles the phenomenon of a phase transition, where different phases (Einstein’s gravitational systems, but with different constants) pass into each other. The hypothesis that such transitions are random and lead to stochastic behavior of cosmological parameters is considered. In our model, effective gravitational and cosmological “constants” arise, which are defined by the “mean square” of the scalar fields. These parameters can be compared with observations related to the phenomenon of dark energy. The aim of the work is to solve equations of MTIG for the case of a quadratic potential and compare them with observational cosmology data. The interaction of fundamental scalar fields and matter in the form of an ideal fluid is introduced and investigated. For the case of Friedmann-Robertson-Walker space-time, numerical solutions of nonlinear MTIG equations are obtained using the qualitative theory of dynamical systems and mathematical computer programs. For the case of a linear potential, examples joining of solutions, the ES and RS stages, of the evolution of the cosmological model are given. It is shown that the values of such parameters as “Hubble parameter” and gravitational and cosmological “constants” in the RS stage contain solutions oscillating near monotonically developing averages or have stochastic behavior due to random transitions to different stages (RS or ES). Such a stochastic behavior might be at the origin of the tension between CMB measurements of the value of the Hubble parameter today and its local measurements.
Global Path Planning for Unmanned Surface Vehicle Based on Improved Quantum Ant Colony Algorithm
Authors: Xia Guoqing , Han Zhiwei , Zhao Bo , Liu Caiyun , Wang Xinwei
Published: April 2019

As a tool to monitor marine environments and to perform dangerous tasks instead of manned vessels, unmanned surface vehicles (USVs) have extensive applications. Because most path planning algorithms have difficulty meeting the mission requirements of USVs, the purpose of this study was to plan a global path with multiple objectives, such as path length, energy consumption, path smoothness, and path safety, for USV in marine environments. A global path planning algorithm based on an improved quantum ant colony algorithm (IQACA) is proposed. The improved quantum ant colony algorithm is an algorithm that benefits from the high efficiency of quantum computing and the optimization ability of the ant colony algorithm. The proposed algorithm can plan a path considering multiple objectives simultaneously. The simulation results show that the proposed algorithm’s obtained minimum was 2.1–6.5% lower than those of the quantum ant colony algorithm (QACA) and ant colony algorithm (ACA), and the number of iterations required to converge to the minimum was 11.2–24.5% lower than those of the QACA and ACA. In addition, the optimized path for the USV was obtained effectively and efficiently.
Incremental Multiple Hidden Layers Regularized Extreme Learning Machine Based on Forced Positive‐Definite Cholesky Factorization
Authors: Liu Jingyi , Le Ba Tuan
Published: April 2019

The theory and implementation of extreme learning machine (ELM) prove that it is a simple, efficient, and accurate machine learning method. Compared with other single hidden layer feedforward neural network algorithms, ELM is characterized by simpler parameter selection rules, faster convergence speed, and less human intervention. The multiple hidden layer regularized extreme learning machine (MRELM) inherits these advantages of ELM and has higher prediction accuracy. In the MRELM model, the number of hidden layers is randomly initiated and fixed, and there is no iterative tuning process. However, the optimal number of hidden layers is the key factor to determine the generalization ability of MRELM. Given this situation, it is obviously unreasonable to determine this number by trial and random initialization. In this paper, an incremental MRELM training algorithm (FC‐IMRELM) based on forced positive‐definite Cholesky factorization is put forward to solve the network structure design problem of MRELM. First, an MRELM‐based prediction model with one hidden layer is constructed, and then a new hidden layer is added to the prediction model in each training step until the generalization performance of the prediction model reaches its peak value. Thus, the optimal network structure of the prediction model is determined. In the training procedure, forced positive‐definite Cholesky factorization is used to calculate the output weights of MRELM, which avoids the calculation of the inverse matrix and Moore‐Penrose generalized inverse of matrix involved in the training process of hidden layer parameters. Therefore, FC‐IMRELM prediction model can effectively reduce the computational cost brought by the process of increasing the number of hidden layers. Experiments on classification and regression problems indicate that the algorithm can be effectively used to determine the optimal network structure of MRELM, and the prediction model training by the algorithm has excellent performance in prediction accuracy and computational cost.
Pleural Cryobiopsy versus Flexible Forceps Biopsy in Subjects with Undiagnosed Exudative Pleural Effusions Undergoing Semirigid Thoracoscopy: A Crossover Randomized Trial (COFFEE Trial)
Authors: Dhooria Sahajal , Bal Amanjit , Sehgal Inderpaul Singh , Prasad Kuruswamy Thurai , Muthu Valliappan , Aggarwal Ashutosh Nath , Agarwal Ritesh
Published: April 2019

Background: There is no randomized study comparing pleural cryobiopsy (CB) and flexible forceps biopsy (FFB) in subjects undergoing medical thoracoscopy for the diagnosis of pleural effusions. Objective: In this crossover study, we compared the diagnostic yield of CB versus FFB in subjects undergoing semirigid thoracoscopy. Methods: Subjects undergoing semirigid thoracoscopy for undiagnosed pleural effusions were subjected to both CB and FFB, with the order of performing the biopsy randomized in a 1:1 ratio. The primary outcome was the diagnostic yield obtained with CB versus FFB. The secondary outcomes included the biopsy size, depth, histologic interpretability, artefacts, the difficulty of performing biopsy on an operator-rated visual analog scale, the severity of bleeding observed at the time of the biopsy, and the duration of the procedure. Results: Of the 201 subjects screened, 50 (mean age 52.4 years; 18 women) were included. The diagnostic yield of CB (78.0%) was not different from FFB (76.0%, p = 1.00). CB yielded a larger specimen than FFB (median size 7.0 vs. 4.0 mm; p < 0.001), and a greater depth of specimens (up to the pleural fat or deeper, CB vs. FFB 65.2 vs. 40.8%; p = 0.02). The CB procedure was quicker than FFB (median duration 10 vs. 15 min; p < 0.001). There were no significant differences in the difficulty of performing the biopsy, the severity of bleeding, histologic interpretability, or artefacts in the specimens between the CB and FFB groups. Conclusion: The diagnostic yield of pleural CB was comparable to FFB during semirigid thoracoscopy.
Assessing Inspiratory Muscle Strength for Early Detection of Respiratory Failure in Motor Neuron Disease: Should We Use MIP, SNIP, or Both?
Authors: Janssens Jean-Paul , Adler Dan , Iancu Ferfoglia Ruxandra , Poncet Antoine , Genton Graf Laurence , Leuchter Igor , Escher Imhof Monica , Héritier Barras Anne-Chantal
Published: April 2019

Background: Motor neuron disease (MND) invariably impacts on inspiratory muscle strength leading to respiratory failure. Regular assessment of sniff nasal inspiratory pressure (SNIP) and/or maximal mouth inspiratory pressure (MIP) contributes to early detection of a requirement for ventilatory support. Objectives: The aim of this study was to compare the feasibility, agreement, and performance of both tests in MND. Methods: Patients with MND followed by a multidisciplinary consultation were prospectively included. Pulmonary follow-up included forced expiratory volumes, vital capacity (VC) seated and supine, MIP, SNIP, pulse oximetry, and daytime arterial blood gases. Results: A total of 61 patients were included. SNIP and MIP could not be performed in 14 (21%) subjects; 74% of the subjects showed a decrease in MIP or SNIP at inclusion versus 31% for VC. Correlation between MIP and SNIP (Pearson’s rho: 0.68, p < 0.001) was moderate, with a non-significant bias in favor of SNIP (3.6 cm H2O) and wide limits of agreement (–34 to 41 cm H2O). Results were similar in “bulbar” versus “non-bulbar” patients. At different proposed cut-off values for identifying patients at risk of respiratory failure, the agreement between MIP and SNIP (64–79%) and kappa values (0.29–0.53) was moderate. Conclusions: MIP and SNIP were equally feasible. There was no significant bias in favor of either test, but a considerable disparity in results between tests, suggesting that use of both tests is warranted to screen for early detection of patients at risk of respiratory failure and avoid over diagnoses. SNIP, MIP, and VC all follow a relatively linear downhill course with a steeper slope for “bulbar” versus “non-bulbar” patients.
An Autopsy Case of Anaplastic Pancreatic Ductal Carcinoma (Spindle Cell Type) Multiple Onset in the Pancreas
Authors: Ito Hiroyuki , Hiraiwa Shin-ichiro , Sugiyama Tomoko , Tajiri Takuma , Yoshii Hisamichi , Izumi Hideki , Yamaji Yoko , Kaneko Motoki , Tsuda Shingo , Ichikawa Hitoshi , Nagata Junko , Kojima Seiichiro , Takashimizu Shinji , Shirai Takayuki , Watanabe Norihito
Published: April 2019

This is a case of a 75-year-old man who was diagnosed with anaplastic pancreatic ductal carcinoma (spindle cell type). His image findings showed pancreatic head cysts and pancreatic head, body, and tail tumors respectively. EUS-FNA was performed to the pancreatic head and pancreatic body tumors, and the same high atypical type cells suspected of cancer were obtained from either specimen, and finally total pancreatectomy was performed. On the specimen, there were 4 lesions in the pancreas; histology showed that the same anaplastic pancreatic ductal carcinoma (spindle cell type) was obtained from the pancreatic head cyst and the pancreatic tumors.
Sepsis-Associated Acute Kidney Injury: A Problem Deserving of New Solutions
Authors: Kellum John A. , Wen Xiaoyan , de Caestecker Mark P. , Hukriede Neil A.
Published: April 2019

Sepsis-associated acute kidney injury (S-AKI) significantly worsens patient prognosis, and recent evidence suggests that the injury process begins early and may be sustained by therapies used to treat the sepsis (e.g., fluids resuscitation, antibiotics). While efforts to develop less-injurious treatments are making progress, some degree of secondary injury is to be expected. So too is the inevitable nature of organ injury, which is often present at the time the patient seeks medical attention. We recently found that most patients presenting with septic shock and developing AKI had evidence of kidney damage at the time of, or within 24 h of their admission. In such patients, prevention is not a viable option, as injury has already occurred by the time of presentation. Since S-AKI patients are at increased risk of developing chronic kidney disease, a fundamental target for interventions in S-AKI is to prevent fibrosis (maladaptive repair) while stimulating regeneration (proliferation of viable epithelial cells). Using a pathway-agnostic, proliferation-based phenotypic assay, we discovered phenylthiobutanoic acid, a small molecule histone deacetylase inhibitor, that enhances renal recovery and reduces fibrosis in both zebrafish and mouse models of AKI.
The Needs For Contextual In Teaching Materials On Writing Kid Stories Grade 4th Elementary School
Authors: Utami Yermia Tri , Slamet St. Y. , Winarno Winarno
Published: April 2019

The aims of research consist of the following (1) to know need analyze teaching materials related to the matter on writing kid stories in the fourth grade of elementary school, (2) to develop teaching material on writing kid stories based on contextual. The study employs descriptive qualitative and evaluative method which the data are collected by interview, observation, document analysis, and Forum Group Discussions (FGD), questionnaire, and test. Result of the research (1) The teachers still need the addition of teaching materials on writing kid stories as support, (2) Teachers need the new innovation about the developing og teaching materials on writing kid stories. Teaching materials on writing kid stories on contextual basis which can help the teachers as the teaching media in enlanging the sight on writing kid stories and the students are motivated in expressing idea, opinion and mind in a story. The results of the development of teaching materials to writing kid stories based on contextual grade 4th can be received well by learners.
Factors Affecting Student’s Academic Performance in Ahuntegen General Secondary School, North Wollo Zone, Ethiopia
Authors: Getachew Birhan
Published: April 2019

The Academic performance of the student depends on a number of factors such as teachers, student and school related variables. Hence, this study was conducted to analyze the factors which affect the academic performance of students. Primary and secondary data were used for the study. In this paper, students’ results were taken from record office. Multiple regressions, chi-square test, correlation analysis were used to analyze the data. The result of the chi-square test and correlation analysis portrayed that teachers educational level, experience, subject matter knowledge, students interest towards education, attendance, parents educational level, parents income, distance of the school from the students home, the availability of materials, text book and language skill of students have an influence for the academic success of students. Besides, keeping other variables constant, 14.8 % and 62.7% variability of students’ academic performance was explained by teacher and school related variables whereas the overall 74.2 % of variations of students’ results were explained by 19 variables applied for this study. The overall relationship was statistically significant (F19, 23=8.592, P0.001). It is recommended that analyzing and understanding of teachers, students, parents, school educational expert and related variables are very essential to improve the academic performance of students.
Cultivating Morals Students through Character Education: A Case Study
Authors: Abdullah Anzar
Published: April 2019

This research aims to describe: First, the application of character education in SMP Negeri 16 Makassar. Second, the impact of the application of character education the school in SMP Negeri 16 Makassar. This was a qualitative research employing the naturalistic approach, carried out in SMP Negeri 16 Makassar. The data were collected through observations in debt interview, and document. The research finding, the following conclusions are drawn: (1). The development of school culture to build character in SMP Negeri 16 Makassar, consisting of planning, application, supervision, and evaluation, runs well. The application of character education in SMP Negeri 16 Makassar runs well, supported by the school personal and school committee. (2). The impacts of character, among others, manifested in: caring cleanliness; religious service obedience; conformity to the rules; mutual respect politeness, and family like relationship; honesty and responsibility; togetherness; and all personal school, including teacher and staff participation.
The Application of Safety Education in Primary School Directorate in Indonesia
Authors: Widowati Evi , Koesyanto Herry , Sugiharto Sugiharto
Published: April 2019

Primary school children are included in the vulnerable group because they are still in a growth and development phase. In Indonesia, many accidents involve children due to their lack of knowledge, excessive energy, and high curiosity. Therefore, it is important to evaluate the application of safety values in formal education material, in order to evaluate how adequate the current teaching materials in encouraging children to practice safety culture.Petompon 2, one of the primary school used in this study, showed that 60% subjects in grade 1 contain application of safety values, and subjects from grade 2 to 6 showed that 14.3%, 90%, 100%, 87.5%, and 50% subjects, consecutively, already contain safety education.The solutions offered are improving teacher’s capacity in learning process and integrating the safety values into education subjects, such as: in sport education, natural science, social science, citizenship education, Islamic religion, mathematics, and Indonesian language. Other methods available are integrating safety values into extracurricular activities and introducing educative game on safety values to primary school students.
The Development of Oriented on Multicultural Islamic Religious Education in School
Authors: Suradi Ahmad
Published: April 2019

This article describes the development of oriented on multicultural Islamic religious education in school. Multicultural-oriented religious education is a vehicle to give awareness to learners about the people of Indonesia is a plural society that has cultural diversity, beliefs, languages, races and tribes. Therefore, demanding a multicultural education, in order to anticipate the occurrence of a sharp conflict among the existing differences. Multicultural education as an education on cultural diversity in responding to demographic changes and environmental cultures of particular communities, even the world as a whole. The values of Islamic religious education with a multicultural insight have a significant influence in the effort to form patterns of religious understanding among learners. The values are not only contained in the curriculum content of Islamic religious education, but also reflected from the understanding of teachers applied with the approach and methods used in the process of Islamic religious education. Positive views and understanding for religious teachers on pluralism and multiculturalism in turn will be able to transform patterns of understanding Indications of failure is inseparable from the role of religious education teachers in providing religious understanding to learners.
Cognitive Conflict Strategy and Simulation Practicum to Overcome Student Misconception on Light Topics
Authors: Wartono Wartono , Batlolona John Rafafy , Putirulan Apilya
Published: April 2019

One way to reduce misconceptions can be overcome by cognitive conflict learning strategies with the help of simulation practicum instead of actual practicum. This study aims to determine whether there are differences in students' misconceptions before and after learning with cognitive conflict strategies as an effort to reduce misconceptions on light material. Research sample of 31 students. Data on the degree of misconception before the study was 0, 36 and after doing research was 0.17. The t-paired test results for the mean percentage of students' misconceptions on light material before and after learning differed at a significance level of 0.05. While, the results of N-Gain calculations to student achievement increase in overcoming misconceptions on light material were 0.3, that means the average students’ achievement in dealing with misconceptions are in the medium category and cognitive conflict strategies combined with simulation practicum have a strong effect on reducing students' misconceptions on light material with a range of 2.91. Based on the results of the study it can be concluded that cognitive conflict strategies combined with simulation practicum can be used to reduce misconceptions that lead to increased student learning achievement. Further research is needed to explore students' misconceptions on other physics topics and can measure student misconceptions at each meeting so that students are more organized and developed in learning.
Analysis of students’ metacognition level in solving scientific literacy on the topic of static fluid
Authors: Pamungkas Zakaria Sandy , Aminah Nonoh Siti , Nurosyid Fahru
Published: April 2019

The purpose of this study is to describe students’ metacognition level in solving scientific literacy. This research use the descriptive method. The subject of this research is 99 students of grade XI in SMA Batik 2 Surakarta. Data collection methods used are test methods which its instruments based on an indicator of scientific literacy and metacognition ability. Data analysis techniques use quantitative descriptive analysis. The results showed that the achievement of scientific literacy in science as a body of knowledge, science as a way of thinking, science as a way of investigating, and science as an interaction between technology and society is still low at below 35%. This is due to 84%  student occupy in low metacognition level that is 30% students in tacit use level, 54% students in aware use level, and only 16% students occupy in high metacognition level that is in strategic use level.
The effect of organization restructuring on organization performance viewed from employee performance and leadership effectiveness at maluku provincial education office
Authors: Notanubun Zainuddin , Ririhena Ribka Lemi , Batlolona John Rafafy
Published: April 2019

The focus of this research is to comprehensively analyze the effect of organization restructuring on the performance of the organization, directly or indirectly, involving 276 employees in the education office and the Ministry of Education and Culture offices and collected by survey method. Data analysis was done using causal correlation technique to see the effect of organization restructuring on organization performance. The results of the research indicate that there is a direct influence of organization restructuring on organization performance. Another result is that there is an indirect effect of restructuring through employee performance and leadership effectiveness on organization performance. The influence of organization performance improvement is due to, organization restructuring implemented in Maluku Province education office has lead to behavior change, where the employees of education office were able to improve individual performance and can work together with the leadership as an efficient and effective structure. This has an impact on improving organization performance.
Improving mathematical literacy of problem solving at the 5th grade of primary students
Authors: Zainiyah Umi , Marsigit Marsigit
Published: April 2019

This quantitative descriptive study aims to describe the Mathematical Literacy of Grade 5 of Primary Students regarding their mathematical problem-solving abilities. The samples of this study were 35 5th-grade-students at Muhammadiyah Condongcatur Elementary School in academic year 2017/2018. The data were collected through observations and tests with five questions containing indicators of mathematical literacy regarding mathematical problem-solving abilities; two experts have validated the test instruments. Moreover, the test estimated Cronbach's alpha of 0.749 proved reliability. The data analysis in this study was carried out descriptively based on the average score, the standard deviation, the maximum score, the minimum score, the total score, and the percentage correct answer. The results showed that the mathematical literacy of the 5th-grade students at SD Muhammadiyah Condongcatur was generally at the high category (indicated by the problem-solving abilities). Students have been able to understand a problem, to use logic to describe the solution to a problem, and to choose the most appropriate solution to solve a problem.
Developing the capacity of school management to build understanding of vision and mission
Authors: Sukaningtyas Dwi , Satori Djam’an , Sa’ud Udin Syaefudin
Published: April 2019

In many schools, the vision mission just "exist" and not become a guideline especially implementation of learning. The school just execute school routine without knowing the meaning of implementation. This is unfortunate, because the vision and mission is a unique destination that covers the activity and can be utilized as the power of quality of the service organization. How is the capacity of school management in developing the vision and mission? The goal of the research is to describe and analyze the capacity of school management in developing the vision and mission. This study used a qualitative approach with case studies. Data collection methods used are interviews, observation, and study of the document/artifact. The validity of the data is done with credibility, transferability, dependability, and confirmability. The results shows that schools which establish vision and mission based on noble values of the founders have a strong base for the development.
What should be the object of research with respect to the notion of mathematical proof?
Authors: Ndemo Zakaria , Mtetwa David J , Zindi Fred
Published: April 2019

Despite its central place in the mathematics curriculum the notion mathematical proof has failed to permeate the curriculum at all scholastic levels. While the concept of mathematical proof can serve as a vehicle for mathematical thinking, studies have revealed that students experience serious difficulties with proving that include: not knowing how to begin the proving process, the proclivity to use empirical verifications for tasks that call for axiomatic methods of proving, resorting to rote memorization of uncoordinated fragments of proof facts. While several studies have been conducted with the aim of addressing students’ fragile grasp of mathematical proof the majority of such studies have been based on activities that involve students reflecting and expressing their level of convincement in arguments supplied by the researchers thereby compromising the voice of the informants. Further, research focus has been on the front instead of the back of mathematics. Hence, there is a dearth in research studies into students’ thinking processes around mathematical proof that are grounded in students’ own proof attempts. Therefore current research strides should aim at identifying critical elements of students’ knowledge of the notion of proof that should be informed by students’ actual individual proof construction attempts.
Dimmer and neon transformer as a power controllable generator for atmospheric pressure plasma jet
Authors: Zin Rosnah Mohd , Soon Chin Fhong , Yusof Nadhia Mohd , Rizon Elfa Rizan , Tee Kian Sek , Ahmad Mohd Khairul , Nayan Nafarizal
Published: April 2019

The feasibility of a dimmer and neon transformer to provide power control to the atmospheric pressure plasma jet (APPJ) is presented in this paper. The standard neon transformer was previously shown applicable to power up a plasma torch to generate plasma irradiation of an APPJ at 8.64kv and 35kHz. However, the plasma emission is not controllable. In this study, a lamp dimmer was proposed to function as a power controller to the neon transformer which drives the generation of plasma and discharged with argon gas. With the dimmer output voltage adjustable from 60 - 220V, the power and current of the dimmer were variable from 8.4 to 83.6 W and 0.08 and 0.38 A, respectively. The temperature measured at the quartz tube and sample exposure site were less than 50oC suggested that the APPJ produced were non-thermal. A simple test by exposing plasma plume to a leaf sample showed that the plasma produced were non-damaging to the leaf. This portable system can provide control to the APPJ and applicable for bioengineering studies. 
Design and analysis of 2-coil wireless power transfer (WPT) using magnetic coupling technique
Authors: Ali A. , Yasin M.N.M , Husin M.F.C. , Hambali N.A.M Ahmad
Published: April 2019

2-coil non-radiative wireless power transfer (WPT) is studied to find the coil diameter ratio to effective distance of power transfer efficiency (PTE). Single circular coil and spiral coil are designed and simulated using CST software to compare the result of coil diameter versus effective distance of PTE by using S21 value. Accordingly, the quality factor (Q) of both coils are presented as Q factor is one of the parameter that affect the performance of WPT system. The result is promising as the effective distance is more than the coil diameter with (PTE) more than 50% using spiral coil as compare to single coil design.
The linear quadratic regular algorithm-based control system of the direct current motor
Authors: Nguyen Trong-Thang
Published: April 2019

This research aims to propose an optimal controller for controlling the speed of the Direct Current (DC) motor. Based on the mathematical equations of DC Motor, the author builds the equations of the state space model and builds the linear quadratic regulator (LQR) controller to minimize the error between the set speed and the response speed of DC motor. The results of the proposed controller are compared with the traditional controllers as the PID, the feed-forward controller. The simulation results show that the quality of the control system in the case of LQR controller is much higher than the traditional controllers. The response speed always follows the set speed with the short conversion time, there isn't overshoot. The response speed is almost unaffected when the torque impact on the shaft is changed.
Economical and efficient technique for a static localized maximum sun lux determination
Authors: Ali Ahmed H. , Nada Adel S. , Shalaby Ahmed S.
Published: April 2019

Solar energy is one of the most promising renewable sources that is currently being used worldwide to contribute for meeting rising demands. In this paper solar irradiance measurement will experimentally carried out in two different regions in Egypt; Cairo and Luxor cities. This paper proposes a simple solar lux measurement using a light dependent resistor (LDR) with an arduino kit. This technique is based on two approaches which are coarse and fine maximum sun lux determination. This is based on the predetermined 260 vertical slop of the LDR. Coarse tuning determines one of the reach sun lux quarter (900) of horizontal quad. The fine tuning allocates the optimized 100 in which; the maximum sun lux can be obtained. The optimal values of sun lux were found between the (90o–180o) quarter. This study confirms that the narrow ten degrees (95o-105o) are the optimized static sun lux extraction for the two site field measurements. This novel technique can be used for locating the angle of best installations for the solar cell at which maximum solar energy can be extracted. 
Mycophagous Drosophilidae (Diptera) guild and their hosts in the Brazilian Amazon
Authors: Santa-Brígida Rosângela , Wartchow Felipe , Medeiros Priscila Sanjuan , Gottschalk Marco Silva , Martins Marlúcia Bonifácio , De Carvalho Claudio José Barros
Published: April 2019

The composition and potential hosts of mycophagous Drosophilidae from a section of the Brazilian Amazon forest in the Caxiuanã National forest were investigated. Sampling was performed in three different periods at long the wet season (January (beginning) and July (end) 2013 and May (middle) 2014). The samples were collected from existing trails by actively searching for fungal fruiting bodies where Drosophilidae were present. We present composition and richness analysis over two years of sampling sampling Drosophilidae and Fungi. We evaluate sampling completeness using asymptotic species richness estimators. Out of 159 fruiting body samples and 64 fungal species, 5,124 drosophilids belonging to 55 species and 5 genera were collected. The mycophagous Drosophilidae richness values estimated by Jackknife 1 and Bootstrap were 69 and 61, respectively. The estimated fly richness correlated positively with fungal richness and abundance. Among the Drosophilidae species identified in this study, approximately 5% represent new occurrences for Brazil and 56% represent new species. Four genera belonging to the Zygothrica genus group are found in the Amazon region, and these genera represent 80% of the fungus-associated fauna known to date for the tropics. In conclusion, our results show that the fungal richness and abundance were the factors that determined the high diversity of mycophagous Drosophilidae.
Brachionus rotundiformis Tschugunoff, 1921 from the Brachionus plicatilis species complex (Rotifera: Monogononta): A new record from Galápagos Archipelago, Ecuador
Authors: López Carlos , Steinitz-Kannan Miriam , Stamou Georgia , Michaloudi Evangelia , Papakostas Spiros , Fontaneto Diego , Segers Hendrik
Published: April 2019

The presence of the rotifer species Brachionus rotundiformis from the B. plicatilis species complex in Lake Arcturo, a saline lake in the Genovesa Island of the Galápagos Islands, is here reported. This is the first record of the species for the rotifer fauna of Ecuador as well as of the species complex to the Galápagos Islands. This finding is consistent with the idea of high dispersion capacity, and of cosmopolitan distribution of this species complex. Because Genovesa Island is uninhabited, passive transport by wind currents and zoochory by migrant birds seem to emerge as the most plausible factors in this process of colonization. Integrative studies on the morphological variations, genetic, molecular, and ecological aspects are still required to further understand the process of dispersion and the ecology of this member of the B. plicatilis species complex in this remote and isolated locality, and the exact taxonomical position of the island’s population to the other members of the complex.
Padrão tensivo dos argumentos indutivo, dedutivo e abdutivo
Authors: Saraiva José Américo Bezerra
Published: April 2019

Com este artigo pretendemos render homenagem ao criador da semiótica tensiva, Claude Zilberberg, falecido recentemente. Procuramos demonstrar o alcance da tese central de suas postulações teóricas, a da omnipresença do afeto em todo e qualquer produto discursivo, das artes às lógicas da ciência. As grandezas afetivas, de fato, têm alta relevância na economia do sentido, pois, conforme tentaremos mostrar, cifram inclusive o grau de coesão interna dos três tipos de argumento identificados por Peirce: dedutivo, indutivo e abdutivo. Estes três tipos de argumento diferem uns dos outros em função do grau de saliência da conclusão no interior da estrutura argumental e do poder de doxalidade referentemente às proposições que preparam a conclusão.
Investigações sobre o racismo: contribuições da semiótica francesa
Authors: Farias Iara Rosa
Published: April 2019

Em pleno século XXI, diante de grandes avanços tecnológicos, ainda nos deparamos com atitudes racistas. O racismo está presente, infelizmente, nas práticas discursivas de várias sociedades, cotidianamente. Neste trabalho, pretendemos  fazer um  percurso histórico do termo raça e como as suas aplicações afetou discursos de uma época. Buscamos entender, por esse viés, como o racismo em relação ao negro se tornou possível e que permanece até os dias de hoje. Para abordar as transformações decorrentes do uso do termo raça vamos nos pautar nos conceitos valência e valor apresentados pela Semiótica tensiva desenvolvida no trabalho de Fontanille e Zilberberg (2001). Para fazer o percurso histórico do conceito raça e abordar o seu uso nos discursos, recorremos aos trabalhos de  Mbembe (2012), Munanga (2000) Ianni (2004) e Bonciani (2016) entre outros pesquisadores.

 

Palavras-chave: Valência. Valor. Paradigma. Raça. Racismo.
Um modelo catenário e tensivo para a estrutura do quadrado semiótico
Authors: Beividas Waldir
Published: April 2019

Este artigo visa explorar uma sugestão de Zilberberg, quando, numa reflexão en passant, propunha que “o categórico pressupõe o gradual que o funda” e que “o categórico é obtido pela suspensão dos termos catenários e conservação dos termos extremos” (1981, p. 10). Catenária – do latim catena [cadeia] – é definida em dicionário como uma curva na qual pende, sob a influência de seu próprio peso, um fio suspenso pelas extremidades. Essa figura geométrica permite “espelhar” o gradiente de tensividade – figura de um L, eixo intensivo na vertical e eixo extensivo na horizontal – acoplado a seu espelho (um L invertido), um segundo eixo intensivo e extensivo. O primeiro L responderia pela “tonicidade” (na verticalidade intensiva) e sua “degradação” (na horizontalidade extensiva) do termo primeiro (S1); o L invertido responderia pela tonicidade e degradação do termo segundo (S2). Em suma, duplica-se o gradiente tensivo para acolher os dois termos categoriais do quadrado semiótico que, assim, se “tensivisa”.
Claude Zilberberg: a semiótica estetizada
Authors: Discini Norma
Published: April 2019

Algirdas Julien Greimas (2014), em estudo sobre o crer e o saber, faz breve alusão à conversão do ato epistêmico em fazer interpretativo e em processo discursivo, para o que coteja o conceito de aspecto com o papel do observador leitor. Na mesma obra, ao discutir a semiose do mundo, alude a um sujeito “paciente”, que, distinto daquele ativo ou agente, é confrontado com o estatuto modal do objeto contemplado. Claude Zilberberg (2011), por sua vez, ancora a noção de aspecto num espaço tensivo, enquanto cria condições para que se descreva o sujeito como o que se apresenta atropelado por um acontecimento extraordinário. Em nossas reflexões, cotejaremos como as questões de processamento aspectual e de formação de um sujeito “paciente”, vindas à luz no âmbito da narratividade, ressoam na semiótica tensiva, enquanto se confrontam estilos esboçados nos gêneros discursivos e configurados como estilos autorais. Somos movidos pelo desejo de homenagear Zilberberg, que, tendo partido recentemente desta vida, deixa para nós um legado epistemológico que nos permite entender a estesia constitutiva da linguagem, do sujeito e dos discursos, advindos todos dos mais diversos campos do conhecimento.
Nascimento: cesura, catástrofe e psicanálise
Authors: Komniski Paula Cristina Nogueira Vieira , Chatelard Daniela Shienkman
Published: April 2019

Este artigo tem como objetivo discutir, à luz da teoria psicanalítica, alguns dos aspectos psicológicos presentes no momento do nascimento. Para tanto, exploraremos o termo “cesura”, utilizado por Freud em 1926 e retomado por diferentes autores para tratar da complexidade dessa experiência, marcada, dentre outros eventos, pela prematuridade do bebê e sua relação de dependência absoluta no início da vida. Dependência esta que se estenderá, de forma relativa, por muitos anos, sem nunca deixar de estar presente nas relações humanas. Trataremos também da importância da figura materna, representante do ambiente, para o acolhimento e sustentação psíquica do bebê que acaba de nascer. A mudança radical de ambiente vivenciada pelo bebê, que passa do mundo aquático para o mundo aéreo – assim como a reorganização dopsiquismo materno que acontece com a chegada de um filho são experiências radicais, resultando no que será considerado por alguns autores como experiência catastrófica. O artigo busca compreender essa maneira de abordar tal acontecimento, procurando explorar o sentido de tal descrição, assim como suasimplicações nas formas afetivas de se relacionar do humano.
Risco, detecção e prevenção: sobre a contribuição da psicanálise no trabalho institucional com crianças desnutridas
Authors: Neves Beatriz Sernache de Castro , Lima Maria Celina Peixoto , Oliveira Débora Passos de
Published: April 2019

O presente trabalho testemunha a experiência clínico-institucional no setor de intervenção psicanalítica do Instituto da Primeira Infância, situado na cidade de Fortaleza – Ceará, cujo ofício se dirige a famílias em condições de vulnerabilidade social e, em particular, a crianças que apresentam estado de desnutrição. Partindo de uma contextualização crítica das noções de vulnerabilidade e risco, o artigo tem como objetivo apresentar um dispositivo institucional voltado para a detecção e prevenção de risco psíquico, orientado pelas contribuições advindas da teoria psicanalítica sobre a constituição psíquica e, mais recentemente, da clínica com bebês. Destaca-se um caso clínico acompanhado pelo setor.
Função do semelhante como fundamento do trabalho com as crianças em grupos
Authors: Tiussi Carolina Cardoso
Published: April 2019

Tese de Doutorado no Instituto de Psicologia da Universidade de São Paulo.
Rompendo idealizações
Authors: Lessa Fábio De Souza
Published: April 2019

Neste texto, pretendemos discutir modelos de representação dos corpos dos atletas gregos nas imagens áticas do período clássico. Defenderemos que o esquema iconográfico que privilegiava o modelo apolíneo do corpo dos atletas gregos, por mais que fosse hegemônico, não era único. Os corpos que se distanciam desse modelo e que foram agrupados por John D. Beazley no “Fat Boy Group” serão priorizados nesta análise.
Louros a Esparta
Authors: Silva Maria Aparecida Oliveira da
Published: April 2019

O objetivo deste artigo é demonstrar a relação entre educação (ἀγωγή) e competição (ἀγών) em Esparta no contexto dos Jogos Olímpicos da antiga Hélade