bluuebunny/crossref_metadata_2025 huggingface dataset:
More Than a Platform
Authors:   , Rosenberg Ren , Yau Pamela
Published: February 2023

This thesis investigates how arts and culture organizations are incorporating social justice and activism into their organizational structure. As our society becomes more polarized, increased social and economic pressures have caused a shift towards a more robust and active approach to social justice from arts and culture organizations. In pursuit of these goals, arts and culture organizations have sought more intentional, wholistic, and transgressive social justice work, as well as more horizontal approaches to creative, operational, and management structures. This thesis uses exploratory research to examine how arts and culture organizations are going about this work, what their motivations are, and how they view the role of arts and culture organizations in social change work. This research includes interviews of three arts organizations in the Philadelphia area actively pursuing structural approaches to social justice: Mendelssohn Chorus of Philadelphia, Eastern State Penitentiary, and the Environmental Justice Department of Mural Arts Philadelphia. Interviews with administrators at these organizations, as well as additional data collected from websites, financial documents, and publicized writings and interviews, demonstrated common themes among these institutions. All three organizations made significant strategic, programmatic, and operational efforts to better address issues of social justice, activism, and inclusion. Each institution's methods for furthering social change followed some precedent in the field but aligned strategically with the individual organization's mission and history. Actions taken by each organization were led primarily and fervently by institutional leaders. Funding for the organizations focused on diversity, equity, and inclusion, as well as criminal justice, were boons and motivators for those organizations, while funding for the Mural Arts Environmental Justice Department proved a continuing challenge. Each organization faced resistance from many stakeholders, but all emphasized resistance from internal, mostly mid-level members and staff. The efforts by all organizations have been slow and methodical processes, involving many research phases and partnerships in order to pursue their goals meaningfully and ethically. Finally, all organizations expressed views that their efforts were not only morally necessary, but imperative for the survival of the organization. The implications of this research suggest that arts and culture organizations are perceiving a heightened need to participate in activism and social justice movements, and using various, mission and history-based methods to meet those needs.
Monoclonal antibody: a cell specific immunotherapy to treat cancer
Authors: Rahman M. Ashikur , Islam Fargana , Hasan Mahedi , Joya Irin S. , Mithila Maisha M. , Islam M. Fahim , Rahman M. Rashedur
Published: February 2023

Fundamentally, the therapy technique which is utilized in malignancy immunotherapy, monoclonal antibodies (mAb), is one of them, and it is used extensively as a treatment for the disease. To achieve more successful treatment, novel combination treatments and treatment procedures must be created. The purpose of this study is the improvement of mAb treatment and detail late advance and new limits, particularly in cancer therapy. With various keywords, we searched Google Scholar, PubMed, and Scopus for monoclonal antibody therapy as an alternate form of chemotherapy. The number of patients who received each therapy regimen, and the recovery rate are all displayed in this study, also a comparative study between monotherapy and chemotherapy. The result showed that rituximab had a greater overall response rate than other drugs, at 68%. In the combination treatment group (monotherapy+chemotherapy), 100% of patients had adverse events, compared to 84.2 percent in the monotherapy group. The pharmaceutical industry's fastest-growing medications, monoclonal antibodies are increasingly being examined in Clinical trials as stand-alone treatments or in conjunction with other therapies. It has a promising future since it will provide better tailored therapy and combination therapy for the treatment of cancer.
Psychological distress in relation to blood pressure among Andhra Pradesh state road transport corporation bus drivers, Vijayawada
Authors: Y. Mary Chaitanya , Harish K.  , J. Bharani Parasuram , Amarnath M.  , Ravikumar J.
Published: February 2023

Background: One of the major health problem worldwide is elevated blood pressure (BP). Prior research had shown that hypertensives experience psychological distress, although pre-hypertensives have not yet been subject to this research. Objectives were to assess the major risk factors of increasing BP among bus drivers and to assess psychological distress in relation to BP levels.
Methods: A cross sectional study was conducted among Bus drivers aged above 20 years, study was carried out between July to October of 2022, a sample of 135 was taken. Inferential statistics such as Pearson Chi square test and an unpaired independent-sample t-test was used to assess the difference between pre-hypertensive and hypertensive individuals on GHQ score.
Results: In the present study (n=135), 47% were normotensive, 34% were in hypertensive stage and 19% were in pre-hypertensive stage. On assessment of psychological distress in relation to BP among bus drivers the mean of (General health questionnaire) GHQ-12 was found to be 17.57 among hypertensives and 17.86 among pre-hypertensives. Two tailed significance value of 0.768 was observed between pre-hypertensive and hypertensive individuals indicating that psychological distress had significant effects.
Conclusions: The prevalence of hypertension and pre-hypertension was among bus drivers, leading to cardio vascular diseases which in turn causes increased morbidity and mortality, lowering individual productivity and having an impact on the national economy. The prevalence of non-communicable diseases should be monitored by lifestyle changes and periodic screenings.
Digitilized Radiographic Analysis of Coronal Pulp for Age Estimation in Adults using Tooth Coronal Index Method – A Pilot Study
Authors: Joparti Sailaja , Kiran Madala Jaya , Rao Guttikonda Venkateswara , Sivaranjani Yeluri , Thakur Moni , Pradeepthi Katakam
Published: February 2023

Background: Teeth have become a valuable index to estimate age of an individual in forensic odontology. Although various methods have been reported in forensic literature for age estimation, radiographic methods are simple and require less expertise. Digitalization of panoramic radiographs and intraoral periapical radiographs helps in obtaining the more precise images and accurate measurements. Secondary dentin continuously gets deposited on pulpal surface throughout the life thus reducing the size of the pulp cavity. The Tooth Coronal Index (TCI) method is the indirect assessment of secondary dentin deposition for age estimation. Aim: This study aims to estimate the Tooth Coronal Index of mandibular first molar and its correlation with chronological age to derive a regression equation. Materials and Methods: A total of 50 adults above 20 years of age were selected from the outpatient department of our college. Digital intraoral periapical radiographs were taken by using Radiovisiography (RVG) for mandibular first molar. The crown height and Coronal Pulp Cavity Height were measured and then TCI was calculated. Further the data were subjected to statistical analysis. Results: Statistically significant difference was observed between age and TCI (p<0.05*) and statistically insignificant difference observed between gender and TCI (p>0.05). Conclusion: The Tooth Coronal Index provides more accurate estimation of age and it is a simple, non invasive and cost-effective method that could be easily applied for both living and dead individuals without any highly specialized equipment.
Significance of Stem Cells in Forensic Dentistry
Authors: Karthika B. , Nisa Shamsul
Published: February 2023

In forensic point of view and for genetic study, biological samples collected at a crime scene serve as a significant tool, in order to resolve crimes by identifying the person. In some scenarios, individual identification gets masked by chimera persons, where the chimera person cells will have different DNA. The use of biological traces which are recorded by a person’s touch while handling items raises the chance of forensic study system. Therefore, DNA profiling can be obtained from items that were touched, which inturn becomes an useful means for forensic mode of investigation. Chimerism investigations are recognized processes to examine the condition of Hematopoietic Stem Cell Transplantation (HSCT) to analyze peripheral blood and recipient’s bone marrow samples for non-malignant and malignant hematologic diseases. In adults, ectomesenchymal cells identified in oral and maxillofacial tissues are promising for future dental stem cell therapies, because the oral tissues area rich source for stem cells. Dental stem cells have various expressive profiles and exist in specific niches. Apart from these applications, this review article highlights dental stem cells significances in forensic dental investigations.
Biological Invasion Threat to Wetlands IN Urban Areas of White River, Mbombela in Mpumalanga Province, South Africa: A Case Study
Authors: Mafuwane Hluphi Constance , Muchie Mammo
Published: February 2023

Purpose: Wetlands are assets in the country, and they help make cities lockable and attractive. The study aims to assess the spread of alien invasive plants that affect the wetlands and construct a policy framework that could be used to preserve and conserve groundwater resources (Wetlands) in urban areas of Mpumalanga Province, specifically White River. This research will answer why alien invasives are a threat to wetlands.

Methodology: The study was conducted in White River on Longtom Street. A single observer conducted fixed-width line transect surveys to investigate species richness and abundance for all the untreated species detected next to the wetland. Three transects per habitat type were visited twice through twice per week.

Main Findings: During the survey, seven different alien invasive species were observed. The leading species was Solanum mauritianum, followed by Chromolaena odorata species; the third most dominant species was Lantana camara and Tecoma stans. Most species observed were illegally dumped by the residents that stay closer to the wetland, and no awareness, information, and training about the importance of wetlands were provided to the residents.

Implications: The framework can do more to help local communities manage urban wetlands, identifying opportunities for mapping and functional assessment to improve restoration and protection efforts. It can facilitate research and peer-to-peer exchange on innovative funding and financing methods for nature-based projects.

Novelty: Findings and recommendations resulting from this study will be summarized into a strategic guide by the end of 2023. It is recommended that all alien invasive plants in the wetland be eradicated. Wetlands must be protected to improve human health and well-being.
Świadomość czy samoświadomość ubezpieczonych
Authors: Wieteska Stanisław
Published: February 2023

There is a term ‘self-avareness’ in the literature of insurance and opinion on the insurance market. On the base of the insurance data it is concluded that Poles hale a low level of awareness. The level increases when random event occurs. The aim of his article is an attempt to define a term ‘self-awareness’ and point its connection with life and property insurances.
Spatial Analysis of Soil Texture using GIS based Geostatistics Models and Influence of Soil Texture on Soil Hydraulic Conductivity in Melur Block of Madurai District, Tamil Nadu
Authors: Rajalakshimi P. , Mahendran P.P. , Mary P. Christy Nirmala , Ramachandran J. , Kannan P. , . ChelviRamessh , Selvam S.
Published: February 2023

Background: Soil texture is one of the important property constitute ultimate size particles. Proportions of these ultimate soil particles depend on the pedogenesis and mineralogical composition of parent material and also decide all other soil properties. Due to the imprudent crop selection and imperfect agricultural methods, the very fertile soil is becoming denser and low productive. Geostatistics is a set of Models and tools developed for statistical analysis of continuous data. A critical aspect of agriculture ecosystem and environment modeling is the accurate prediction for the spatial variability of soil properties. Methods: In this study, Geostatistical modeling based Kriging techniques has been used to identify the textural variation of soil in the present scenario of Melur Block of Madurai district. Totally, 150 soil samples were collected across Melur block of Madurai district based on grid soil survey and geo coordinates. Result: Geostatistical soil textural maps have been generated based on Kriging tools and these would be utilized for Land Use Pattern, precision agriculture, conservation practices, as well as land management in the research region. The characterization of the spatial variability and influence of soil texture on hydraulic conductivity is essential to accomplish a better understanding of intricate relations between soil properties and environmental factors.
Technical and environmental features of the application of renewable energy for decentralized power supply zones
Authors: Dolgikh N. N. , Osipov D. S. , Osipova N. D.
Published: February 2023

A feature of the geographical location of the Khanty-Mansiysk Autonomous Okrug - Yugra is the presence of a large number of zones of decentralized power supply. For a comparative environmental assessment of renewable energy installations, it is necessary to take into account the emissions of the entire life cycle. Throughout the presented cycle from mining to the production of power plant structures and then the disposal of the facility, a significant part of CO2 emissions is present. The problem of dismantling and recycling of spent structures of wind power plants is becoming essential. Wind turbines cause the death of birds, violate the conditions of comfortable living for people and animals

From a technical point of view, it is necessary to take into account the regime parameters: indicators of the quality of electricity at the point of connection, voltage levels at load nodes, operating modes of energy storage devices. To assess the operating parameters of an isolated power supply system with renewable energy sources, this paper proposes to use the wavelet transform method. The Haar wavelet was used as a basic function in the paper. A mathematical model is presented that makes it possible to obtain a low-frequency (trend) component and a high-frequency component using the wavelet transform. The model allows for the optimal choice of a hybrid energy storage device for a renewable energy source - a battery and a supercapacitor.
La construcción de sujetos sociales en los programas de formación de la lengua extranjera: retos y oportunidades
Authors: Ramos Holguín Bertha , Aguirre Morales Jahir
Published: February 2023

Este artículo reporta los resultados parciales de un proyecto de investigacióncuyo objetivo es interpretar la manera como los actores sociales en los programas de Licenciatura en Lenguas Extranjeras comprenden los sentidos de la educación. Por lo tanto, este artículo es un primer intento por entender que los programas de formación de docentes de inglés se han concebido desde modelos económicos que se enfocan en la construcción de habilidades relacionadas con el conocimiento de la disciplina, en vez de proveer espacios que fortalezcan la construcción de sujetos sociales. Concluimos que para los programas de formación de docentes de inglés esnecesario orientarse hacia lo que les permita a los futuros maestros ser conscientes de sus interculturalidades a fin de convertirse en sujetos sociales. Esto requiere que los futuros docentes negocien con sus comunidades, evalúen de manera crítica el material que utilizan y comprendan sus contextos locales.
Normalización filosófica o la naturalización de la colonialidad filosófica: consideraciones desde la filosofía intercultural
Authors: Rosero José
Published: February 2023

El carácter marcadamente racional que el paradigma eurocéntrico atribuye a la filosofía occidental, legitima la marginación de toda forma de pensamiento que no se ajuste al arquetipo que representa la tradición filosófica iniciada en la Grecia clásica, descartando así cualquier eventual aporte de las culturas orientales, africanas y americanas. Dentro de estas últimas, la invisibilización filosófica del pueblo mapuche encuentra como factor adicional la alteración sistemática de su imagen que la literatura chilena realizó entre los siglos XVI y XX, negando, entre otros rasgos, precisamente su capacidad reflexiva. De esta manera, a pesar de no conformar un grupo unitario como tal, la identificación de conceptos morales que podrían –de modo general– dar forma a un pensamiento ético mapuche requiere de un distanciamiento con el eurocentrismo, tanto de su influjo en la epistemología como en la noción misma de filosofía que ha desarrollado.
Students’ perspectives regarding the institutional English courses in Universidad Surcolombiana
Authors: Yara Falla Karla Tatiana , Collazos Perdomo Maria Ximena
Published: February 2023

This narrative research study allows us to learn about the usefulness of the mandatory institutional English courses at the Universidad Surcolombiana, Neiva branch, for students of other undergraduate programs in English and their academic, professional, and personal impact. It uses the open interview anonymously to collect their experiences and to promote free expression by using questions related to the courses and based on their environment and previous contact with English using Spanish to better understand. Likewise, the English for Specific Purposes model was taken into account and presented as an idea to the students as a strategy to implement it in the different programs. The results indicated that the benefits obtained in these courses were very limited for English learning and improving the level of students, evidencing the need for English according to their program for the adequate professional development of each one.
Evaluación del impacto del Covid-19 en la educación básica de México y Colombia
Authors: Villa-Guardiola Vera Judith , Romero-González Zilath , Hernández-Ramírez Sandra Lucero
Published: February 2023

El presente artículo evalúa la situación de la educación básica en las repúblicas de México y Colombia, a raíz de la emergencia sanitaria causada por el Covid-19. La investigación se desarrolló a través del método analítico-sintético, bajo el paradigma holístico de investigación, que permitió la comprensión del fenómeno estudiado mediante técnicas e instrumentos de análisis y comparación de datos. En ambos países se observan desigualdades en materia de acceso a la educación, causadas en especial por la falta de servicios y herramientas digitales y la falta de conocimiento del uso de las nuevas tecnologías por parte de estudiantes y maestros. Lo anterior se convierte en una limitante del progreso, de los cambios sociales y en causal de un mayor distanciamiento de la esperada justicia social, imposibilitando percibir, difundir y respetar los derechos humanos y brindar alta calidad educativa a las nuevas generaciones de ciudadanos.
Factores intrínsecos a la sobrecarga laboral en el estrés del profesorado
Authors: Suárez Oscar , Suárez-Riveros Lilian , Lizarazo-Osorio Julio
Published: February 2023

El objetivo de este estudio fue encontrar los factores intrínsecos al estrés laboral del profesorado activo en Colombia, México y Perú, distintos a la sobrecarga laboral (SL). Además, buscó establecer, con un modelo no supervisado, cómo los factores identificados predicen la SL. El enfoque fue principalmente cuantitativo, apoyado en el análisis de componentes principales y en la regresión lineal por introducción para construir el modelo. El instrumento indagó las categorías: emociones laborales, demandas laborales, recursos laborales, burnout y recursos tecnológicos para la actividad laboral. Los resultados muestran un alfa global de 0,856. Se obtuvieron diez factores intrínsecos que explican el 71,331 % de la varianza, de los cuales, seis contribuyen a predecir la SL: trabajo en casa, apoyo social, resiliencia didáctica tecnológica, motivación del estudiante, autocontrol emocional e incertidumbre laboral. A manera de conclusión, se encontró que el profesorado tuvo la capacidad resiliente tecnológica y didáctica, que le permitió adaptarse a la presencialidad remota; y que el trabajo colaborativo entre docentes contribuye a disminuir el estrés académico por SL. No obstante, la incertidumbre laboral incide en la SL.
The Relationship Between Coronary Slow Flow and Myocardial Ischaemia Evaluated with Timi Frame Count and Myocardial Perfusion Scintigraphy
Authors: YILMAZTEKİN Mehmet Zeki , KAYAPİNAR Osman , AKTÜRE Gülşah , COŞKUN Gökhan , AŞIK Muhammet , AFŞİN Hamdi
Published: February 2023

Objective: Coronary slow flow (CSF) is known as a form or early stage of common atherosclerotic disease. Myocardial perfusion scintigraphy (MPS) is a valuable technique in the diagnosis of coronary artery disease and prediction of prognosis. The aim of this study was to investigate the relationship between the myocardial defect score and ischaemia in patients with CSF.

Methods: A total of 168 patients who applied with the complaint of angina pectoris and underwent SPECT as a non-invasive test followed by coronary angiography were included in this retrospective study. 9 patient was excluded from the study for various reasons. The study population comprised determined with CSF and no obstructive stricture in the coronary arteries and with normal flow. The mean age of the patients was 56±12 years. The scores obtained from Quantitative Perfusion SPECT (QPS) and Quantitative Gated SPECT (QGS) software were used in the myocardial perfusion evaluation. The TIMI frame counts were compared with the myocardial defect and ischaemia scores. The TIMI frame count method was used in the determination of CSF.

Results: In patients with slow flow in the circumflex (Cx) coronary artery, the stress total perfusion defect Cx (sTPD-Cx) was found to be 0.1 (range, 0.0-1.3), and in those with normal flow, it was 0.0 (range, 0.0-0.28) (p=0.002). The stress score Cx (sscore-Cx) was found to be 1.0 (range, 0.0-3.0) in patients with slow flow and 0.0 (range, 0.0-2.0) in those with normal flow (p=0.031). A linear correlation was determined between the Cx TIMI frame count and the sTPD-Cx and sscore-Cx values (r=0.207, p=0.009; r=0.159, p=0.045). No relationship was found between slow flow and the defect and ischemia scores in other myocardial regions.

Conclusion: In patients with slow flow in the Cx coronary artery, the sTPD-Cx and the sscore-Cx values were found to be significantly high. Although at a weak level, a linear correlation was found between the Cx TIMI frame count and the sTPD-Cx and the sscore-Cx values
Vladimir Sergeyeviç Solovyov ve Rus Kozmizmi
Authors: MÜMİNOĞLU Kasım
Published: February 2023

Kozmizm felsefesinin kökü Antik Yunan felsefesine dayanmakla birlikte 20. yüzyılın başlarında bir dizi dini-felsefi, mistik, sanatsal, estetik ve bilimsel gelecek hakkında düşünceler ileri süren hareket olup insan ve insanlık hakkındaki fikirlerin varlığına dayanan tek bir toplulukta birleştirilir. İnsanın âlemdeki yeri ve önemi bir mikro-kozmoz olarak belirlenmeye çalışılır. Rus Kozmizmi felsefi geleneği de dünya felsefe literatüründe bu manada kendi yerini geçte olsa XIX. yüzyıl ortalarında almıştır. Rus düşünürü Vladimir Sergeyeviç Solovyov’un Rus Kozmizmindeki yeri ve önemi oldukça büyüktür. Solovyov Platon, Aristoteles ve Plotinus gibi Antik dönem filozoflarından etkilenerek Rus Ortodoks düşüncesini yeni Kabalacı unsurla işleyerek kendi ‘sophia’ düşüncesini inşa etti. Bu makalenin amacı Solovyov’un “Birlik Metafiziği” hakkındaki düşüncelerinin kültürel ve felsefi açıdan Rus Kozmizmine temel taşı olup olmadığı konusunu incelemektir. Araştırmamızda Solovyov’un ‘Tanrı’, ‘Ruh’, ‘Maneviyat’ ve ‘Sophia’ kuramlarının ontolojik yapısının Antik dönem felsefesi ile olan bağları üzerinde durmayı hedeflemekteyiz.
Odnos med depresivnostjo, naučeno nemočjo, spolom in šolskim uspehom pri mladostnicah in mladostnikih
Authors: Jehart Daša , Fekonja Urška , Komidar Luka
Published: February 2023

V raziskavi smo proučevali povezanost naučene nemoči in depresivnosti pri mladostnikih in mladostnicah z njihovim spolom ter učnim uspehom. Zanimal nas je tudi odnos med naučeno nemočjo in depresivnostjo ter pri katerih šolskih predmetih se mladostniki in mladostnice počutijo najbolj nemočne. V vzorec je bilo vključenih 297 dijakov in dijakinj, starih med 16 in 18 let. Za ocenjevanje depresivnosti smo uporabili Lestvico depresivnosti (CESD), naučeno nemoč pa smo ocenili z Vprašalnikom odpornosti na naučeno nemoč (CCQ). Oblikovali smo tudi kratek vprašalnik za učitelje razrednike in učiteljice razredničarke, s katerim smo pridobili podatke o zaznani naučeni nemoči ter pogostosti pojavljanja takšnih vedenj pri vsakem mladostniku in mladostnici posebej. Rezultati so pokazali, da obstaja statistično značilen pozitiven odnos med depresivnostjo in naučeno nemočjo pri mladostnikih in mladostnicah. Mladostnice so v večji meri poročale o simptomih depresivnosti in vedenjih naučene nemoči kot mladostniki, za učno bolj uspešne mladostnike in mladostnice pa je bila značilna nižja raven depresivnosti kot za učno neuspešne. Učno neuspešni mladostniki so v povprečju izražali več naučene nemoči kot učno uspešni mladostniki, medtem ko je bil pri mladostnicah učinek učnega uspeha ravno obraten. Obenem so rezultati pokazali, da mladostniki in mladostnice največ naučene nemoči doživljajo pri slovenščini, fiziki in matematiki, sledijo jim nemščina, kemija, biologija in angleščina. Najmanj nemočne pa se počutijo pri glasbi, zgodovini, športni vzgoji, likovni vzgoji in geografiji. Glede na to, da mladostniki in mladostnice v šolskem okolju preživijo velik del svojega časa, je pomembno izpostaviti vlogo učiteljev in strokovnih delavcev, ki bi jih bilo smiselno opolnomočiti za prepoznavanje in preventivno delovanje pri preprečevanju razvoja depresivne simptomatike in naučene nemoči pri njihovih dijakih.
Depression and Suicide in Regards to Sex
Authors: Matošić Ana , Pašić Hanna , Silić Ante , Vidrih Branka , Puljić Antonia , Vilibić Maja
Published: February 2023

Psychiatric disorders represent one of the leading problems of the public health community in the modern world today, especially because their incidence is steadily increasing and they are one of the main reasons for the overall disease burden in Europe. One of the most frequently diagnosed, yet under recognized diseases, is depression. Depression, whether a symptom, part of a syndrome or an independent diagnosis, is characterized by feelings of sadness, loss of interest and pleasure in activities that normally bring joy to a person, and can affect how a person feels, thinks and behaves. It affects all age and social groups, as well as both sexes, it is often comorbid with other physical diseases, and increases the risk of developing other physical diseases. There are certain differences between the sexes in the prevalence, the way a certain sex group deals with problems caused by depression, and the possible causes of these differences, which we present in more detail in this paper. Differences are observed in all cultures, environments and across different age groups. Patients suffering from depression have a particularly high risk of committing suicide. Suicide is a psychopathological phenomenon of multifactorial aetiology that is most often associated with psychiatry and mental disorders and is not a diagnosis in itself, but a complication of many psychiatric disorders. here are many differences in the rate of suicide by age and sex, as well as in the method of suicide, which we also present in more detail in this paper.
Sex Differences in the Therapy of Advanced Movement Disorders
Authors: Vuletić Vladimira
Published: February 2023

The influence of sex differences in movement disorders is still under-recognized. There are significant sex differences in the pathophysiology, epidemiology, clinical manifestations, and treatments outcome of many of movement disorders especially Parkinson’s disease. Importance of sex specific differences in invasive treatment outcomes emphasize the importance of their considering when devising patient’s individual management strategies. Increased recognition and future prospective studies specifically addressing sex differences in invasive treatments’ outcomes may help and provide a tailored therapeutic and precision medicine approach to movement disorders. We highlight the most relevant invasive treatment’s effects in advanced movement disorders that differ between men and women. But also, the differences in selection of invasive methods. Increased recognition of sex differences and their impact on treatment of advanced phase of movement disorders, that are very disabling, is very important for future studies and precise and personalized medicine. In this article, we provide a review of sex- related differences in treatment of advanced movement disorders, mostly Parkinson’s diseases.
Brain Infarction in the Artery of Percheron Supply Area due to Reversible Cerebral Vasoconstriction Syndrome
Authors: Meštrović Andrija , Raifi Zurap , Sruk Ana , Budišić Mislav , Kalousek Vladimir , Roje Bedeković Marina , Budinčević Hrvoje
Published: February 2023

An ischemic stroke caused by the occlusion of the artery of Percheron encompasses both posterior thalami, and the resulting clinical presentation can mask the clinical presentation of a stroke. We present the case report of a 62-year-old female patient who was admitted to our emergency department in a soporous state after initial headache and dizziness. A neurological exam found left-sided spasticity and a flexor response to pain. Systemic thrombolysis was administered after an urgent computerized tomography (CT) of the brain with angiography. The interventional radiologist proposed a digital subtraction angiography which found a vasospasm in the right medial cerebral artery from the M2 seg- ment reaching distally, and a balloon dilation was done. Following the endovascular procedure, a CT scan showed ischemia in both posterior thalami. Additionally, the patient’s neurological impairment improved at that moment showing Parinaud syndrome, drowsiness, and left-sided palsy. The patient experienced a possible reversible cerebral vasoconstriction syndrome, the cause of which is still unknown, which resulted in an ischemic stroke. The typical clinical presentation of that syndrome was lacking, probably due to the presence of the artery of Percheron ipsilateral to the vasospasm. Our goal in presenting this case study is to draw attention to the artery of Percheron syndrome as a potential clinical sign of an acute ischemic stroke that can easily lead us to be misled.
Female with Fibromuscular Dysplasia
Authors: Pintarić Melanija , Vukasović Rafaela , Lovrenčić-Huzjan Arijana
Published: February 2023

Fibromuscular dysplasia (FMD) is a noninflammatory, nonatherosclerotic disorder that cause arterials steno- sis, occlusion, aneurysm, dissection, and artery tortuosity. The etiology of FMD remains unknown. The most frequently involved arteries are the renal, internal carotid, vertebral arteries and visceral. Among adults, FMD is more common in females. Most common symptoms are renovascular hypertension, headache, pulsatile tinnitus, neck pain, and abdominal pain. We present a 62-year old female patient who was diagnosed with grade 3 arterial hypertension at the age of twenty -nine. During diagnostic treatment, narrowing of the right renal artery was determined and percutaneous transcutaneous angioplasty of the right renal artery was performed. Diagnosis of fibromuscular dysplasia was suspected. After this procedure, the value of blood pressure was normalized. At the age of forty, the patient was re-introduced with antihypertensive, and CT angiography showed 50 % lumen stenosis of the right renal artery. She was referred to a neurologist. The patient has been complaining about frequent headaches, pulsatile tinnitus in the right ear, increased fatigue, and occasional abdominal pain for many years. Neurosonological testing showed partially wall thickening in the left common carotid artery and multiple stenosis and dilatation of the left internal carotid artery. The left vertebral artery has multiple stenoses and dilatations in the distal V1 segment. The findings indicated changes in fibromuscular dysplasia and the diagnosis of FMD was confirmed.
Modeling and innovation using artificial intelligence in accelerating handling the COVID-19 pandemic: A bibliometric study
Authors: Sadat Anwar , Lawelai Herman
Published: February 2023

This study aims to analyze previous publications with the theme of modeling and innovation using artificial intelligence in accelerating the handling of COVID-19. The data of this study come from the Scopus database. This study uses VOSviewer to evaluate keywords from 575 publications in the Scopus database with research topics. Next, analysis of Scopus database search results visualizes features and trends of related journals, authors, and themes. This study found that articles on modeling and innovation using artificial intelligence in accelerating the handling of COVID-19 have been published in 267 journals, with the most popular journals being Chaos, Solitons, and Fractals. The results of bibliometric analysis show that there are ten popular journals, with The Lancet Infectious Diseases receiving the most citations. Likewise, in this study there are authors who have the most article documents, namely J.S. Suri with 4 (four) documents, and X. Xu is the most popular author with the most citations. The results of this study show that an AI approach can help in the dissemination of important information around the world while reducing the spread of misinformation about COVID-19. This study suggests that focused, effective, and efficient collaboration, coordination, and harmonization are needed between the central government, local governments, and commercial entities.
Entropic Dynamics in a Theoretical Framework for Biosystems
Authors: Summers Richard L
Published: February 2023

Central to an understanding of the physical nature of biosystems is an apprehension of their ability to control entropy dynamics in their environment.  To achieve ongoing stability and survival, living systems must adaptively respond to incoming information signals concerning matter and energy perturbations in their biological continuum (biocontinuum).  Entropy dynamics for the living system are then determined by the natural drive for reconciliation of these information divergences in the context of the constraints formed by the geometry of the biocontinuum information space.  The configuration of this information geometry is determined by the inherent biological structure, processes and adaptive controls that are necessary for the stable functioning of the organism.  The trajectory of this adaptive reconciliation process can be described by an information-theoretic formulation of the living system’s procedure for actionable knowledge acquisition that incorporates the axiomatic inference of the Kullback Principle of Minimum Information Discrimination (a derivative of Jaynes’ principle of maximal entropy). Utilizing relative information for entropic inference provides for the incorporation of a background of the adaptive constraints in biosystems within the operations of Fisher biologic replicator dynamics.  This mathematical expression for entropic dynamics within the biocontinuum may then serve as a theoretical framework for the general analysis of biological phenomena.
Autonomous Pick and Place for Mechanical Assembly WRS 2020 Assembly Challenge
Authors: Sidki Nahid
Published: February 2023

The World Robot Summit (WRS) 2020 Assembly Challenge aims to realize the future of industrial robotics by building agile and lean production systems that can (1) respond to ever-changing manufacturing requirements for high-mix low-volume production, (2) be configured easily without paying a high cost for system integration, (3) be reconfigured in an agile and lean manner, and (4) be implemented as agile one-off manufacturing for the industry. One of the technical challenges of assembly is the detection, identification, and classification of a small object in an unstructured environment to grasp, manipulate, and insert it into the mating part to assemble the mechanical system. We presented an end-to-end system solution based on flexibility, modularity, and robustness with integrated machine vision and robust planning and execution. To achieve this, we utilized the behavior tree paradigm and a hierarchy of recovery strategies to ensure effective operation. We selected the behavior tree approach because of its design efficiency in creating complex systems that are modular, hierarchical, and reactive, and offer graphical representations with semantic meaning. These properties are essential for any part assembly task. Our system was selected for the WRS 2020 Assembly Challenge finals based on its successful performance in qualifying rounds.
Development of Automatic Inspection Systems for WRS2020 Plant Disaster Prevention Challenge Using Image Processing
Authors: Shimizu Yuya , Kamegawa Tetsushi , Wang Yongdong , Tamura Hajime , Teshima Taiga , Nakano Sota , Tada Yuki , Nakano Daiki , Sasaki Yuichi , Sekito Taiga , Utsumi Keisuke , Nagao Rai , Semba Mizuki
Published: February 2023

In this article, an approach used for the inspection tasks in the WRS2020 Plant Disaster Prevention Challenge is explained. The tasks were categorized into three categories: reading pressure gauges, inspecting rust on a tank, and inspecting cracks in a tank. For reading pressure gauges, the “you only look once” algorithm was used to focus on a specific pressure gauge and check the pressure gauge range strings on the gauge using optical character recognition algorithm. Finally, a previously learned classifier was used to read the values shown in the gauge. For rust inspection, image processes were used to focus on a target plate that may be rusted for rust detection. In particular, it was necessary to report the rust area and distribution type. Thus, the pixel ratio and grouping of rust were used to count the rust. The approach for crack inspection was similar to that for rust. The target plate was focused on first, and then the length of the crack was measured using image processing. Its width was not measured but was calculated using the crack area and length. For each system developed to approach each task, the results of the preliminary experiment and those of WRS2020 are shown. Finally, the approaches are summarized, and planned future work is discussed.
Langerhans Cell Histiocytosis Presenting as a Lesser Trochanter Fracture in an Adolescent
Authors: McCambridge Teri Metcalf , Papakyrikos Cole , Levin Adam
Published: February 2023

Case:

We present the case of an 18-year-old man with right hip pain who was found to have a lytic lesion of the lesser trochanter of the right femur with cortical destruction and a lytic lesion of the left inferior pubic ramus. Additional imaging and pathology testing confirmed a diagnosis of multifocal, single-system Langerhans cell histiocytosis (LCH) of the bone.

Conclusion:

LCH is a rare pediatric disease most commonly diagnosed in toddlers and young school-age children. Its epidemiologic characteristics are poorly described for young adults and older adolescents, in whom clinical suspicion should be maintained when evaluating multifocal osseous lesions.
Neglected Metatarsophalangeal Joint Dislocation of the Lesser Toe with Associated Metatarsal Fracture Malunion in a 4-Year-Old Child
Authors: Chandankere Vidyasagar , Rachakonda Kamalakar Rao , Maryada Venkateshwar Reddy , Reddy Guruva A.V.
Published: February 2023

Case:

A 4-year-old girl presented with a 5-week-old, neglected fourth metatarsophalangeal (MTP) joint dislocation with malunion of the fourth metatarsal. A previous attempt at closed reduction had failed. The reduction was hindered by dynamic stabilizing of soft tissues around the MTP joint. Open reduction of the fourth MTP joint dislocation and corrective osteotomy of the fourth metatarsal was performed. The patient was pain-free without any cosmetic deformity at the 1-year follow-up.

Conclusion:

Prompt recognition of a MTP dislocation is vital. The long extensor tendon to the toe can hinder the closed reduction of the MTP dislocation. Osteotomy of the metatarsal malunion is necessary for stable reduction.

Level of Evidence:

4
Suspected Brown Recluse Spider Envenomation: Missed Diagnosis and Delayed Treatment of Loxoscelism
Authors: Gómez-Muñoz Eduardo , Pérez-Úbeda María José , Garríguez-Pérez Daniel , Echevarría-Marín Marta , Gimeno María Dolores , Marco Fernando
Published: February 2023

Case:

We report the case of a previously healthy 51-year-old man who presented to our hospital after worsening clinical appearance of his left ring finger, despite antibiotics and previous surgical drainage for suspected abscess at an outside institution 3 weeks ago. He was admitted to our hospital for surgical debridement and decompression. After suspicion of cutaneous loxoscelism based on the clinical record and corticosteroid administration, the patient presented a favorable evolution.

Conclusion:

Cutaneous loxoscelism caused by a spider bite is present in Europe, mainly in the Mediterranean area, and should be considered in cases of skin infections which do not respond to antibiotics.
An Unexpected Postsurgical Phenomenon After Total Knee Arthroplasty: Nummular Eczema
Authors: Kost Yana , Shokrian Neda , Nazarian Roya S. , Mattis Daiva M. , Amin Bijal , McLellan Beth N. , Kamara Eli
Published: February 2023

Cases:

Two elderly women each presented with a unilateral, erythematous rash 1 year after total knee arthroplasty (TKA) for osteoarthritis. Both cases were diagnosed as postsurgical nummular eczema (NE) and treated successfully with topical corticosteroids.

Conclusion:

We highlight a novel clinical presentation of postsurgical NE associated with TKA, previously reported only with breast reconstruction. Postsurgical NE may mimic periprosthetic infection or implant-related allergic contact dermatitis. Timely diagnosis and appropriate treatment in these cases prevented unnecessary testing and hospital admission for revision surgery. This case series highlights the varied presentation and wide differential diagnosis associated with postsurgical NE.
A Novel Hemiarthroplasty Design for Treatment of Post-traumatic Elbow Ankylosis and Distal Humerus Nonunion
Authors: Gabig Andrew M. , Malmquist Jacob A. , Brady Christina I. , Dutta Anil K.
Published: February 2023

Case:

A 26 year old man sustained a blast injury to the right elbow, resulting in chronic distal humerus nonunion and post-traumatic ankylosis. After debridement and flap coverage, a custom distal humerus hemiarthroplasty construct with extramedullary orthogonal plating was used. Satisfaction and functional outcomes were maintained through 6 years of follow-up.

Conclusion:

This case presents a unique 1-stage surgical solution which demonstrates the potential for uncemented extramedullary hemiarthroplasty fixation with simultaneous compression plate osteosynthesis across a nonunion site. The potential for hemiarthroplasty designs to be linked to orthogonal plates preserves the intramedullary canal for future conversion to total elbow arthroplasty if necessary.
Repair of a Reverse Humeral Avulsion of the Glenohumeral Ligament and a Supraspinatus Tear in a Division I Collegiate Football Player
Authors: Bouck Trevor T. , Beyer Julia , Miller Jacob D.
Published: February 2023

Case:

We present the case of a 21-year-old male, collegiate division I wide receiver, with a humeral avulsion of the posterior glenohumeral ligament (RHAGL) and near-full-thickness supraspinatus tear after falling on his outstretched arm. He returned to full collegiate participation with symptom resolution after arthroscopic repair of each tear.

Conclusion:

This case report emphasizes the importance of imaging studies in the diagnosis of RHAGL and details a treatment approach that provided an excellent result in a young, active patient. This information will bring attention to these rare injuries and provides reference for providers who encounter patients with similar symptoms or pathology.
Diffuse Pulmonary Metastases at Presentation of Giant Cell Tumor of Bone
Authors: Leland Christopher R. , Pratilas Christine A. , Gross John M. , Levin Adam S.
Published: February 2023

Case:

We present a 23-year-old man with acute-on-chronic shoulder pain with an aggressive-appearing, destructive lesion of the left proximal humerus and diffuse lung metastases. Biopsy revealed conventional giant cell tumor of bone (GCTB) without sarcomatous differentiation, treated with resection and proximal humerus reconstruction. Without systemic treatment, his pulmonary metastases demonstrated modest spontaneous regression, with no impairment of pulmonary function.

Conclusions:

Although GCTB is known to metastasize to lungs, these deposits most commonly follow local recurrence. We describe a young adult with diffuse pulmonary nodules at initial presentation, although still following an indolent clinical course without the need for additional systemic therapy.
Cephalic Vein Intravascular Foreign Body After a Penetrating Injury
Authors: Stark Michael , Matzon Jonas L.
Published: February 2023

Case:

A 65-year-old man presented with a right forearm metallic foreign body after a projectile injury while using a table saw. The area in question appeared infected prompting a surgical incision and drainage. In the operating room, the metallic foreign body was noted to be entirely intravascular within the lumen of the cephalic vein. It was ultimately removed, and the patient recovered without complication.

Conclusion:

Although foreign bodies after traumatic injury are common, it is exceedingly rare to encounter an intravascular foreign body. However, the consequences of proximal migration can be devastating and thus should be in the differential diagnosis for all treating surgeons.
Pediatric Medial Malleolus Reconstruction and Cartilage Preservation Using Iliac Crest Bone Graft After Ankle Trauma
Authors: Moody Derek , Cornelius Canon , Traver Jessica , Younas Shiraz
Published: February 2023

Case:

This case report describes cartilage preservation and medial malleolus reconstruction using tricortical iliac crest autograft in a pediatric patient who sustained an ankle injury resulting in near-complete medial malleolus bone loss.

Conclusion:

Medial malleolar bone loss precluding open reduction and internal fixation is a challenging surgical problem, and there are few studies describing treatment. Our case report adds to the literature because our described technique resulted in a successful outcome for this patient.
Mucormycosis in the Hand
Authors: Jerome J. Terrence Jose , Thirumagal K.
Published: February 2023

Case:

We report a 25-year-old insulin-dependent woman with extensive soft tissue infection in the left hand. The tissue cultures grew methicillin-resistant Staphylococcus aureus, and histology identified mucor species. The patient received a course of intravenous liposomal amphotericin B and vancomycin. Wound debridement, intravenous antimicrobial, and timely groin flap coverage to wound salvaged the hand and allowed her to return to daily work.

Conclusions:

Mucormycosis of the hand is rare and is associated with high morbidity and amputation. Little is known about reconstructing the mucor-infected wounds in hand. The pedicled groin flap is safe and reliable and can reconstruct complex defects on the hand, especially mucor-resultant wounds.