bluuebunny/crossref_metadata_2025 huggingface dataset:
Acuchimay: asentamiento prehispánico de época Warpa y Wari en la cuenca de Ayacucho
Authors: Carhuas Tenorio Héctor
Published: January 2022

Se presenta parte de un trabajo de investigación que involucra a la arqueología de la Sierra surcentral del territorio andino, correspondiente al marco cronológico del Periodo Intermedio Temprano y Horizonte Medio. Acuchimay es uno de los asentamientos prehispánicos adyacentes al sitio arqueológico de Rudaqasa, localizado en el corazón de la actual ciudad de Ayacucho, que guarda el testimonio de una ocupación antigua de época Warpa y Wari, al igual que otros sitios, ubicados a lo largo de la cuenca del río Huarpa. El objetivo fundamental es conocer y recuperar toda la información posible existente para definir la importancia del sitio durante las épocas Warpa y Wari. El método empleado es descriptivo y síntesis a partir de la visita realizada alrededor de Acuchimay y del material cultural recuperados de la superficie; asimismo, se complementa con algunas colecciones particulares existentes en las propiedades de la población moderna del sitio. En base a las evidencias arqueológicas alcanzamos una visión general acerca de la característica del sitio para comprender sobre lo que fue la dinámica sociocultural en la antigua cuenca de Ayacucho.
Agentenbasierte cyberphysische Produktionssysteme
Authors: Vogel-heuser Birgit , Schütz Daniel , Schöler Thorsten , Pröll Sebastian , Jeschke Sabina , Ewert Daniel , Niggemann Oliver , Windmann Stefan , Berger Ulrich , Lehmann Christian
Published: January 2022

Obwohl die Anforderungen in der modernen Produktionstechnik durch wechselnde Kundenwünsche bestimmt werden, unterstützen aktuelle Automatisierungslösungen vor allem die geforderte Flexibilität für Losgröße 1 nicht in ausreichendem Maße. Der Beitrag gibt einen Überblick über eine prototypische Architektur für agentenbasierte cyber-physische Produktionssysteme. Mit dieser Architektur wird die standortübergreifende horizontale und vertikale Integration von Produktionssystemen vorgestellt und verschiedene sich daraus ergebende Potenziale werden aufgezeigt.
Das Internet der Dinge, Dienste und Menschen
Authors: Drath Rainer
Published: January 2022

Industrie 4.0 prognostiziert die Einführung von Internettechnologien in die Produktion, mit vielversprechenden Potenzialen und komplexer Interaktion. Die Folgen sind schwer abschätzbar. Eine Kernfrage lautet: Werden die Mittel und Methoden, mit denen wir steigende Komplexität beherrschen schneller wachsen als die Komplexität, die wir beherrschen wollen? Ein Fragenkomplex beschäftigt sich dabei mit der Rolle des Menschen in der zukünftigen Produktion. Im Beitrag diskutieren die Autoren am Beispiel des Roboters YuMi, der sich durch seine Fähigkeit zur Zusammenarbeit mit dem Menschen auszeichnet, welche Potenziale und Konsequenzen sich durch die intelligente Verbindung von Geräten, Software und dem Menschen im Kontext von Industrie 4.0 ergeben.
Notfallplan Wassergewinnungsanlage Mannsgrab (Bad Saulgau)
Authors: Treskatis Christoph
Published: January 2022

Am Beispiel der Wassergewinnungsanlage Mannsgrab wird die Erarbeitung eines Notfallplanes im Sinne des DVGWHinweises W 1001 „Sicherheit in der Trinkwasserversorgung“ zum Schutz der Trinkwasserbrunnen vor Beeinträchtigungen durch Stoffe aus Verkehrsunfällen aufgezeigt. Ein Abwehrbrunnen ist formell vorhanden; es besteht aber weder eine Ableitungsmöglichkeit in einen Vorfluter oder Kanal noch ist eine Aufbereitungsanlage vorhanden. Hydrogeologische Untersuchungen zeigten, dass Störstoffe aus Unfällen in den hoch durchlässigen Schottern rasch versickern können. In ungünstigen Fällen beträgt die Verweilzeit in der ungesättigten Zone weniger als zwei Stunden. Es wurde geschlussfolgert, dass ein effizienter Notfallplan zur Vermeidung einer unfallbedingten Grundwasserverunreinigung vor allem eine sehr schnelle Reaktion der Feuerwehr erfordert, um die Stoffe einzudämmen, aufzunehmen und den kontaminierten Bodenbereich zu sanieren.
Energiemanagementsystem für den Zweckverband Wasserver- und Abwasserentsorgung „Mittleres Erzgebirgsvorland“ (ZWA) Hainichen
Authors: Voltz Thomas , Musche Fabian , Pötzsch Ulrich , Hälsig Ramona , Bahner Philipp , Jungmann Claus , Eichler Axel , Marx Axel , Radisch Mandy , Grischek Thomas
Published: January 2022

Zwischen Juni 2014 und Oktober 2015 wurde beim Zweckverband für Wasserver- und Abwasserentsorgung „Mittleres Erzgebirgsvorland“ (ZWA) Hainichen ein Energiemanagementsystem (EnMS) gemäß der DIN EN ISO 50001 eingeführt und zertifiziert. Die gesamte Energienutzung des ZWA wurde sichtbar gemacht und kann nun gemanagt werden. In zahlreichen Beratungen mit ZWA-Mitarbeitern wurden Arbeitsprozesse analysiert, Schwächen und Stärken aufgezeigt. Das Energieeffizienz-Netzwerk des ZWA wurde deutlich gestärkt und ein Mitarbeiter als Energiemanager gewonnen. Energieeffizienz besitzt nun einen höheren Stellenwert und wird durch Maßnahmen kontinuierlich gefördert.
Promoting Admiration of Foucault Hiding his Defense of Rape and Pederasty
Authors: Valls Rosa , Elboj Carmen , Serradell Olga , Díez-Palomar Javier , Aiello Emilia , Racionero Sandra , Vidu Ana , Roca Esther , Joanpere Mar , López de Aguileta Ane
Published: January 2022

Foucault has been quoted as a great intellectual contributor to feminism and education, despite his defense of decriminalizing rape and pederasty. Since the MeToo movement, there is an increasing criticism of Foucault’s persona and works. However, in order to avoid recognizing their mistake, some authors say that Foucault’s defense of sexual violence was unknown before. This article shows this is not backed by evidence. Data was collected via interviews with 19 subjects with diverse profiles, employing the communicative methodology. The results shed light on the fact that some professors who have included Foucault’s works in their classes hid Foucault’s position in favor of sexual violence to their students. Interviewees state that there are several reasons why they think those professors hid this fact: a) the most critical thinker; b) the transgressor; c) a relativist intellectual; d) “a shield to hide behind”; and e) the idea that the intellectual must be separated from the person. This study indicates that in transmitting those images and hiding or even justifying Foucault instead of critically analyzing the implication of his works and his defense of sexual violence, perpetuating its justification, such professors act as his “hooligans”.
Digital Competencies for New Journalistic Work in Media Outlets: A Systematic Review
Authors: Reyes-de-Cózar Salvador , Pérez-Escolar Marta , Navazo-Ostúa Pablo
Published: January 2022

Media organizations operate in a rivalry-charged ecosystem nowadays, as a consequence of emerging patterns of news production, distribution, and consumption. Furthermore, the growing of public social media manifestations and the arrival of digital journalism require new professional roles, responsibilities, and skills inside the media industry. In this context, Faculties of Communication need to equip students with the digital competencies that are relevant to new media outlets and journalistic work. Based on this approach, the main objective of this study is to answer the following questions: What does the literature suggest about the digital skills that new professional profiles should acquire in the field of journalism? Which dimensions of digital competence are gaining visibility and which dimensions are being neglected? To answer the scientific objectives, a systematic review has been carried out following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The application of the two models of digital competence, Bloom’s taxonomy (1956), and digital competence in education (Redecker, 2017), serves as a framework in two ways: to determine the level of digital competence development, and to identify the dimensions on which greater emphasis is being placed. The results show a lack of studies linked to key aspects of digital competence, especially those related to personal growth, emotional state (Redecker, 2017), and the development of a deep level of acquisition of this competence (Bloom, 1956). This article proposes to reflect on whether we want to train professionals according to the model demanded by the media outlets nowadays, or whether we prefer to train communication professionals with a deep level of digital competence, since they are able to respond to the future and changing needs of the 21st century.
Preoperative planning of arterial chemoembolization with drug-saturated microspheres for women with recurrent pelvic tumors complicated by bleeding
Authors: Zvezdkina E. A. , Kedrova A. G. , Lebedev D.  P. , Greyan T. A. , Panchenkov D. N. , Stepanova Yu.  A.
Published: January 2022

Arterial chemoembolization is an X-ray surgical method that is used for recurrent pelvic tumors complicated by bleeding. It combines occlusion of tumor vessels and local chemotherapy, for which a cytostatic and drug-saturated microspheres are used. To obtain a result, two conditions must be met: carefully close all tumor afferents, treat the maximum tumor volume with saturated microspheres.

The aim of the work: to define the key points of preoperative planning for recurrent pelvic tumors in women in order to achieve reliable hemostasis and cytoreduction.

An analysis of 17 women with recurrent tumors complicated by tumor bleeding is presented. The first group consisted of 7 patients in whom the uterus was not removed, the second group consisted of 10 patients with removed uterus. For preoperative planning, magnetic resonance imaging of pelvis and selective angiography of the branches of the anterior and posterior trunk of the internal iliac artery were used. The sources of blood supply to the tumor were different and depended on the localization of the process in the upper, middle, and lower levels of pelvis. Multidisciplinary planning made it possible to achieve reliable hemostasis in all cases, to prevent complications from the pelvic organs.
Heterogeneity of EpCAM-positive cells in low-grade serous ovarian carcinoma ascitic fluid: a clinical case
Authors: Kaigorodova E. V. , Kovalev O.  V. , Chernyshova A. L. , Vtorushin S. V. , Shpileva O.  V.
Published: January 2022

Ovarian cancer is one of the most malignant and aggressive tumors of the female reproductive system. Late diagnosis is one of the most significant problems: more than two-thirds of cases are detected only at stage III–IV. Ovarian cancer is characterized by a unique metastatic process. Implantation is the earliest and most common way of metastasis. It is often accompanied by fluid accumulation in the abdominal cavity, known as ascites. We report a case of low-grade serous ovarian carcinoma with a large heterogeneity of tumor cells in the ascitic fluid detected using multicolor flow cytometry. We demonstrated the advantages and benefits of this method in the diagnosis of ovarian cancer. Multicolor flow cytometry opens new horizons for liquid biopsy in oncology.
Computer analysis and of oil and gas refining processes
Authors: Korneev Dimitri Sergeevich , Kotvanova Margarita K.
Published: January 2022

The article is a review of the scientific works of Professor A. A. Novikov. The possibilities and prospects of computer simulation of industrial operations of oil and gas processing, proposed by Professor A. A. Novikov are shown. The results on the physicochemical properties and composition of oils from Western Siberia are presented. Use of them makes it possible to choose the most efficient and rational ways of extraction, transportation and oil processing.
La admiración portuguesa de Lope de Vega
Authors: Cuiñas Gómez Macarane
Published: January 2022

This article investigates Lope de Vega’s relationships with Portuguese authors. To do this, it studies the lyrics of his final stage, that of the thirties of the 17th century, and the elegiac poems of Portuguese writers published at his death.
Application Portfolio Profiling and Appraisal as Part of Enterprise Adoption of Cloud Computing
Authors: Chimakurthi Venkata Naga Satya Surendra
Published: January 2022

Computation resources have never been more affordable, powerful, or readily available than they are now, thanks to the Internet and the rapid advancement of processing and storage technologies. In response to this new trend in technological development, a brand-new computer paradigm is known as "cloud computing" has emerged. Resources are made available to end-users as general utilities that can be rented and released on-demand over the Internet. More and more corporate processes are being moved to the cloud as firms experience using the technology. Cloud adoption is substantially more complicated than we first thought when it comes down to data management, system integration, and managing various cloud providers. As cloud migration has grown more common, a number of have been plagued by failed application modernization initiatives or migration. However, many firms worldwide are finding that cloud computing is more expensive and more difficult to implement than they expected. Is cloud computing still up to the task in this scenario? Failures are largely due to a lack of planning in the early stages of identifying which legacy applications are best suited for private or public cloud deployment, resulting in cost and time overruns. Application portfolios need deliberate decision-making to reduce the risk of overruns and delays in migration. Consequently, a rough estimate of cloud operating costs (ROM) is required for inclusion in the planning phase of IT governance. ROM cloud run costs must first be gathered through an automated discovery process, followed by quantitative analysis. Accordingly, to assist in making an informed decision about whether or not to migrate legacy applications, we propose two methods: (1) gathering initial data through Application Portfolio Profiling (APP), and (2) performing Application Portfolio Assessment (APA). An Enterprise Cloud Computing Considerations Framework (CCCC) framework is used to help a corporation decide which legacy applications should be moved as part of the adoption process for Cloud Computing. In light of the shift in business models, infrastructure requirements, and other issues that arise when cloud computing is implemented, this decision is crucial.
Penerapan Model Pembelajaran Blended di MII Subah pada Masa Pandemi Covid-19
Authors: Ratih Koesoemo , Prayitno Harun Joko , Prasetyo Wibowo Heru , Irmawati Ika , Safitri Azka Dina
Published: January 2022

The covid-19 pandemic caused many problems on to the implementation of learning in schools. A blended learning strategy is by mixing two or more learning models. The learning model was implemented at Madrasah Ibtidaiyah Islamiyah (MII) Subah by combining face-to-face learning and online learning since it is more efficient and effective during the new normal during the Covid-19 pandemic. However, schools experience several obstacles, such as limited facilities and infrastructure to support the implementation of online learning and limited time for face-to-face learning at school. Therefore, schools need well-calculated time management to be utilized optimally. This service aimed to apply the blended learning model in increasing student interest and encouraging maximum learning outcomes. The service applied the advocacy method by providing direct assistance to students. The results of the advocacy indirectly proved that the application of blended learning strategies to help students in minimizing the obstacles of fully online learning. This service provided many benefits for students to appreciate time and opportunities for better learning.
Organ Transplantation in Russia: An Anthropological Perspective
Authors: Mikhel Dmitriy
Published: January 2022

This article offers an anthropological perspective on organ transplantation in Russia. The author employs approaches and principles of medical anthropology and ontological turn in anthropology and attempts to present a novel human-object history of organ transplantation. This research focuses primarily on human collectives, such as medical communities and the rest of society, but also on certain objects, including donor organs and the infrastructure created by the technology. The article discusses the following questions: How does transplantation technology transform the medical community? How is it built into the social and cultural context? How is it perceived by the rest of society? How do some doctors try to adapt this technology to the traditional values of Russian society? This research was conducted at two large Russian organ transplantation centers. The analyzed materials include anthropological and medical publications, and mass media sources.
„W oku” kinematografu… „Leśmian” Leszka Barona (1990) (wstępny rekonesans)
Authors: Grodź Iwona
Published: January 2022

The main topic of the article is to indicate the lyrical and — somewhat on the margin — biographical strategies used by Leszek Baron in the ﬁlm Leśmian from 1990, the aim of which was, on the one hand, to tell about a selected fragment of the life of the Polish poet Bolesław Leśmian (1877–1937); and, on the other, the use of ﬁlm means as an equivalent of the poetic imaging characteristic of the author of W malinowym chruśniaku. The research material is primarily the ﬁctional ﬁlm about Leśmian. The aim of the text is to show how Baron understood the psychology of Leśmian’s work and the speciﬁcity of his poetry. This entails the need to problematize individual dimensions of the production, that is, to analyze the perspectives adopted by the director. Ultimately, it leads to answering the question: how does Baron try to present the ﬁgure and work of Leśmian to new recipients who already belong to a different space-time?
Kryminał, komedia, parodia — przekroczenia gatunkowe w filmie kryminalnym „Na noże” Riana Johnsona
Authors: Szyngiel Elżbieta
Published: January 2022

The article deals with the problem of genre transgressions in contemporary crime cinema. The issue is discussed using the example of the ﬁlm Knives Out, directed by Rian Johnson. The author brieﬂy discusses the development of criminal literature in a detective version and its way to the cinema screen, focusing at the same time on changes taking place in the ﬁeld of portraying a detective. In the next step, the author discusses the character of investigator Benoit Blanc, one of the ﬁlm’s protagonists. His ﬁgure to some extent fulﬁlls the model of a classic detective, but at the same time questions it in many respects.
The author points out that the way of presenting Blanc is dictated by modiﬁcations in the structure of the ﬁlm itself, which deviates from the formula of classic crime cinema, where social themes appear, enriched with comedy and parody themes.
In conclusion, the author notes that the detective crime ﬁlm subgenre still offers many opportunities for formal, narrative and aesthetic experiments. As a result, it is eagerly used by creators looking for new forms of expression, which is particularly important in the context of the weight of the genre and the commercial requirements of the audience.
Eksperymenty letrystów i ich wpływ na autonomizację filmowej mowy we francuskim kinie autorskim
Authors: Poborca Tomasz
Published: January 2022

This article is an attempt to analyze Lettrist ﬁlm experiments — especially Traité de Bave et d’Éternité and Le ﬁlm est déjà commencé? — and the concept of montage discrépant in the context of the development of sound-editing techniques. The author, referring to early ﬁlm theory and Gilles Deleuze’s notion of sound-image, tries to ﬁll in the ideological blank between them with Isidore Isou’s manifesto. The ideas and works of Isidore Isou and Maurice Lemaître in the 1950s are compared with later ﬁlms directed by French avant-garde artists. The comparison reveals heavy inﬂuence and allows us to treat the Lettrist experiments as the missing link in the process of autonomization of cinematic sound. In the course of this analysis, the author proposes a new translation of French terminology on account of the previous one not expressing the meaning properly and leading to probable misunderstandings.
PEMIKIRAN FILSAFAT POLITIK ABDOLKARIM SOROUSH
Authors: Bunardi Adi
Published: January 2022

The ideas of freedom, justice, democracy and secularism are the main themes in the study of political philosophy. This article attempts to explain Abdolkarim Soroush's political philosophy with the boundaries of themes regarding freedom, justice, secluralism and democracy. Abolkarim Soroush is a thinker in the contemporary Islamic world.
FILSAFAT JIWA IKHWAN AL-SHAFA SEBAGAI BASIS KONSEP PENDIDIKAN
Authors: Rum Muhamad
Published: January 2022

Penelitian ini bertujuan untuk membantah pernyataan kaum materialisme yang cenderung menolak keberadaan jiwa sebagai dimensi yang penting bagi manusia khususnya yang berkaitan dengan pendidikan. Adapun latar belakang masalahnya adalah aliran materialism menyatakan bahwa realitas fisiklah yang hakiki dan kelompok ini juga menolak adanya realitas immateri. Dalam kaitannya dengan pendidikan fisiklah yang berperan secara total dalam proses abstraksi. Dengan pendidikan dimaksudkan dapat menjadikan manusia semakin baik dan mampu meningkatkan ekonomi yang lebih baik pula. Disamping itu, Pendidikan kaum borjuis disebut sebagai proses produksi, yakni memproduksi pengetahuan, manusia yang bisa mereka gunakan dalam kehidupan kapitalisme. Tujuan pendidikan semacam ini akan mereduksi makna pendidikan sebagai sarana untuk mengembangkan kemampuan dan potensi yang dimiliki manusia. Potensi ruhaniah manusia akan terlupakan dan tidak penting untuk dikembang dengan maksimal. Oleh karenanya penulis menyanggah argumen diatas menggunakan pemikiran Ikhwan AL-Shafa yang menyatakan bahwa pendidikan pada dasarnya adalah proses aktualisasi potensi-potensi jiwa yang bertujuan untuk mendekatkan diri kepada sang pencipta. Jika keberhasilan pendidikan materialisme diukur dengan berhasilnya seseorang dalam peningkatan kualitas sosial dan meningkatkan kualitas hidupnya sedangkan keberhasilan pendidikan menurut Ikhwan Al-Shafa adalah apabila manusia mampu mencerminkan akhlak yang mulia dan semakin dekat dengan tuhannya.  Metode yang penulis gunakan dalam penelitan ini adalah metode deskriptif dan analaisis dengan mengacu pada sumber-sumber primer Rasail Ikhwan Al-Shafa dan sekunder yang terkait dengan penelitian ini.  Kesimpulan penelitaian ini adalah pendidikan tidak bisa dilepaskan dengan aspek immateri berupa jiwa yang mana segala potensi yang terdapat pada manusia bersumber pada potensi jiwa, selain itu jiwa juga menjadi penggerak raga dalam melaksanakan setiap aktifitasnya. Dengan demikian, jiwalah yang menjadi dasar dalam pendidikan manusia bukan berbasis pada materi.
ETOS KERJA PADA NOVEL PERSEMBAHAN TERUNTUK BAPAK KARYA ADI ZAMZAM DAN PEMANFAATANNYA SEBAGAI BAHAN AJAR DI SMA
Authors: Fauziah Cucu , Muhtarom Imam , Mujtaba Sahlan
Published: January 2022

Permasalahan yang timbul seperti kemiskinan, pengangguran, kesenjangan sosial dan lain-lain disebabkan oleh rendahnya etos kerja. Penelitian ini bertujuan untuk mendeskripsikan unsur-unsur intrinsik dan etos kerja pada novel Persembahan Teruntuk Bapak karya Adi Zamzam dan manfaatnya sebagai bahan ajar di SMA. Metode yang digunakan pada penelitian ini yaitu dengan menggunakan metode kualitatif deskriptif. Penelitian ini menggunakan subjek karya sastra yaitu novel karya Adi Zamzam yang berjudul Persembahan Teruntuk Bapak. Fokus yang diangkat pada penelitian ini yaitu berupa permasalahan yang berkaitan dengan etos kerja. Teknik pengumpulan data untuk penelitian ini dilakukan dengan teknik baca dan catat. Analisis data dilakukan dengan cara reduksi data, penyajian data, dan kesimpulan atau verifikasi data. Data pada penelitian ini berupa kalimat dan paragraf narasi. Hasil penelitian ini menunjukkan adanya  etos kerja yang tinggi pada novel Persembahan Teruntuk Bapak yang tercermin melalui para tokoh di antaranya yaitu: pantang menyerah, sabar, tanggung jawab, kerja sama, kerja keras, terampil, jujur, disiplin dan bijaksana. Hasil penelitian ini memenuhi kriteria sebagai bahan ajar sastra kelas X di SMA, khususnya pada kompetensi dasar menulis teks novel melalui model Cooperative Integrated Reading and Composition (CIRC). Kesimpulan penelitian ini sebagai berikut. Novel Persembahan Teruntuk Bapak menyajikan para tokoh utama yang memiliki etos kerja tinggi sehingga para guru dimungkinkan menggunakannya sebagai sumber pembelajaran sastra di SMA.
ANALISIS RAGAM PLATFORM E-LEARNING DALAM PEMBELAJARAN BIOLOGI KELAS XI SMA DAN MA NEGERI DI KOTA SEMARANG
Authors: Zahro' Anisatuz , Khoiri Nur , Wijayanti Erna
Published: January 2022

The emergence of Coronavirus-19 disease has caused all educational institutions to switch the face-to-face learning mode to distance learning with an online system. Online learning requires teachers and students to use a tool to help teaching and learning activities, namely the e-learning platform. The purpose of this study is to analyze the various e-learning platforms used by biology teachers in grade 11 of public senior high schools (SMA) and Islamic public high schools (MA) in Semarang City. This research is a qualitative descriptive study using the analysis of the Miles and Huberman model. The purposive sampling technique was used by considering the geographical location of the school and the diversity of platforms used. The samples were 5 schools: 3 high schools (SMA) and 2 Islamic Public high School of Madrasah Aliyah. Data collection techniques used semi-structured interviews and documentation studies. The results show that the e-learning platforms used by biology teachers are very diverse, ranging from instant messaging platforms such as WhatsApp, video conferencing platforms such as Google Meet and Microsoft Team, and Learning Management System (LMS) platforms such as Moodle, Google Classroom, Microsoft Office 365, and Madrasah e-learning. Each school uses a different type of platform and is adapted to school policies and student needs. Some schools develop their own e-learning platforms for online learning so that their use is mandatory, but this does not limit teachers from integrating other platforms so that learning objectives can be achieved perfectly.
Students’ Learning Outcomes and Activities: The Use of Video Conference during COVID-19 Pandemic
Authors: Arieny Mutiara , Tibrani Mgs. Muhammad , Santri Didi Jaya
Published: January 2022

This research was motivated by problems during the covid-19 pandemic, it showed that the students’ activity and learning outcomes of the topic of Ecosystem at Public High School  10 Palembang remain  low. Based on observations of the electronic learning process carried out at the school, the teacher mostly applies asynchronous learning, thus the interactivity between teacher and students is not performed well. This study aimed to find out the effect of using video conferencing on the topic of Ecosystem toward the activities and learning outcomes of students. This study was set up as a quasi-experiment, using a nonequivalent control group design with two groups. The experimental group (Grade 10 of MIA 2) which do e-learning using video conference and the control group (Grade 10 of MIA 4) where e-learning without using video conference. Both groups were selected randomly. Data collection instruments were learning activity observation sheets and biology learning outcomes tests. Learning activity was analyzed quantitatively, while the learning outcomes data were also run quantitatively on a prerequisite test, hypothesis testing and the N-gain test.  The results show the average percentage of experimental class learning activities increased from 39.5% to 42.5% while the control class did not increase. The Ancova test showed a significance value of 0.000 or less than = 0.05 and the N-gain test was 0.36. Based on the results, the use of video conferencing on the topic of Ecosystem significantly affected the learning outcomes improvement.
STUDI ANALISIS PENGEMBANGAN E-MODUL IPA BERBASIS INKUIRI TERBIMBING DENGAN SUMBER BELAJAR POTENSI LOKAL TERHADAP KEMAMPUAN LITERASI SAINS
Authors: Herdiana Lilis Eka , Sunarno Widha , Indrowati Meti
Published: January 2022

Penelitian ini merupakan studi analisis terkait e-modul (elektroknik modul) berbasis inkuiri terbimbing yang memanfaatkan potensi lokal untuk meningkatkan kemampuan literasi sains siswa. Penelitian ini merupakan tahap awal menganalisis (analysis) yang termasuk dalam model ADDIE. Instrumen yang digunakan dalam penelitian ini adalah kuesioner yang diisi online melalui link google form oleh guru dan siswa di beberapa sekolah di Kabupaten Ponorogo. Data yang didapatkan dianalisis menggunakan analisis deskriptif kualitatif. Hasil menunjukkan bahwa 93% responden menyatakan perlu dan setuju apabila dilakukan pengembangan elektronik modul (e-modul) IPA berbasis inkuiri terbimbing dengan memanfaatkan sumber belajar potensi lokal untuk meningkatkan literasi sains siswa. Hasil studi analisis digunakan untuk rancangan pengembangan e-modul IPA berbasis inkuiri terbimbing dengan memanfaatkan sumber belajar potensi lokal Kabupaten Ponorogo, yaitu: Telaga Ngebel.
The Effect of Lemon Aromatherapy, Nausea and Vomiting on Trimester I Pregnant Women in Paramitra Clinic
Authors: Wati Puri Kresna
Published: January 2022

Background: Nausea and vomiting occur in 60-80% of primigravidas and 40-60% in multigravidas. The survey results obtained from 36 pregnant women 21 pregnant women experiencing nausea and vomiting. The research objective was to determine the effect of lemon aromatherapy on the intensity of nausea and vomiting in pregnant women in the first trimester of the Clinic and RB Paramitra Medika 1 in 2020.

Sample and method: The study design was pre-experimental research design (one group pre-test and post-test design). The sample of pregnant women who experience nausea and vomiting is 30 pregnant women by quota sampling. The instrument used was the Standard Operating Procedure (SOP) and the PUQE SCORE questionnaire using the Paired Samples T-test with a significant level of 0.05.

Result: The results showed that the pre-test mean value was 7.97 and posttest was 5.7 with an average decrease in the nausea and vomiting scale of 2.3, the statistical test obtained the t value for nausea and vomiting= 6.643 and p=0.000, where p<0.05, then H1 is accepted.

Conclusion: There is an effect of lemon aromatherapy on the intensity of nausea and vomiting in pregnant women in the first trimester at the Paramitra Clinic.
THE IMPROVED PERFORMANCE OF EDITORS IN FINISHING DRAFTS FOR PUBLICATION
Authors: Djatmika Djatmika , Santosa Riyadi , Marmanto Sri , Wiratno Tri , Wibowo Agus Hari
Published: January 2022

Improvement of editors in performing their jobs. Training on effective language exploitation was conducted to editors of publishers in Klaten Regency. Drafts representing their job before and after the training were colleted to be compared on their language performance in improving the texts. The results show that in general the editors have better performance in finishing the drafts for publication. They are more sensitive in identifying grammar mistakes as well as lexical inappropriateness, so that the texts are more effectively revised and improved.
Study of the Optimum Thermal Insulation Thickness of a Calorimeter Wound with Linen Insulation
Authors: THIAM Mame Fadiamé , FAYE Seydou , DIONE Babou
Published: January 2022

In this article, the object of the study is focused on the influence of local insulating materials in the design of a calorific model for the conservation of hot water for a fixed period. The short hollow cylinder is wound with thermal insulation flax between the two walls of the cylindrical device to insulate the interior temperature. The objective of this study is to see the behavior of the thermal resistance of the material as a function of the insulation thickness. The cylinder is modeled by applying the transient analytical method with the heat equation. This analytical resolution of the thermal equation makes it possible to determine the detailed expression of the thermal resistance but also to visualize the evolution curves of this resistance according to the thickness of the insulation under the influence of the contact resistance thermal and heat exchange coefficient on the outside cylinder wall. The results obtained show that the optimum insulation thickness of linen at a temperature of 90 °C is 3.7 cm under the influence of the thermal resistance of the material and 4 cm under the influence of the exchange coefficients thermal.
Composição bromatológica de silagens de milho comerciais produzidas no Brasil
Authors: Faria T.F.R. , Pinese F. , Gimenes F.M.A. , Demarchi J.J.A.A. , Campos F.P. , Premazzi L.M. , Mattos W.T. , Gerdes L.
Published: January 2022

Objetivou-se realizar a análise exploratória dos resultados bromatológicos e uso de modelos para estimativa de nutrientes digestíveis totais de amostras de silagens de milho, por meio dos dados gerados a partir de 12 anos de análises comerciais do Laboratório de Nutrição Animal do Instituto de Zootecnia (IZ), em Nova Odessa, SP, Brasil. Como critério, utilizaram-se dados de amostras de silagens de milho sem nenhum tipo de aditivos, somando 220 amostras nos períodos de 2004 a 2015 e agrupados em quatro triênios. Estes foram caracterizados quanto à sua composição bromatológica através de análise estatística descritiva, correlações de Pearson e pela utilização de modelos de estimativas de NDT, utilizando-se quatro modelos de equações: uma da Universidade de Clemson, uma segundo Harlan e duas segundo Kearl (1 e 2). O valor nutricional das amostras de silagens de milho mostrou-se de qualidade mediana, com valores de FDN (49,2 a 57,2% da MS) acima do ideal de 37 a 45% da MS. Todas as equações puderam ser utilizadas na estimativa do NDT (variação de 54,3 a 67,0% nos triênios) sendo que a de Kearl 1 e Clemson apresentaram a maior e a menor variação entre os triênios, respectivamente. O aumento do valor nutritivo e de NDT nos triênios 3 e 4 indica melhoria na qualidade da silagem.
Uso del polimorfismo del gen de la β-caseína en términos de preservación del ganado lechero marrón
Authors: Ladyka V. , Pavlenko Y. , Sklyarenko Y.
Published: January 2022

Los componentes biológicamente importantes de la leche son la grasa, la proteína, la lactosa y los minerales. Gracias a ellos, es una parte significativa y esencial de la dieta humana. En los últimos años, entre los componentes de la proteína, la beta-caseína ha ganado gran importancia y popularidad entre las personas que se preocupan por su salud. Por lo tanto, la composición beta-caseína de proteínas lácteas y productos lácteos se ha convertido en una característica de cría importante de los animales lácteos. Este estudio tiene como objetivo evaluar las perspectivas para el uso del polimorfismo del locus de beta-caseína en la selección de ganado marrón para determinar la posibilidad de crear rebaños de piscina genética con características únicas de la leche – exclusivamente con beta-caseína A2. La estructura genética identificada de las vacas y toros de la raza Lebedyn por beta-caseína, la participación de los toros de la raza original de la raza suiza marrón (BS) según el modelo recíproco propuesto, permite formar poblaciones homocigotas de genotipos A2A2 en generaciones posteriores. Un enfoque individual para las cuestiones de coincidencia y selección, control, con la ayuda de métodos de diagnóstico de ADN, por los procesos de transmisión de genes de padres a descendientes, permitirá reponer rebaños con portadores del gen A2. El modelo de cría propuesto en combinación con el uso de espermatozoides sexados y el genotipado de novillas, tiene la mayor aceleración de selección de la creación de una población homocigota para beta-caseína A2A2.
Penerapan Strategi Joyfull Learning Dalam Penanaman Sikap Tanggung Jawab Siswa (Studi Kasus Pembelajaran IPS di SMP Negeri 1 Mlarak)
Authors: Arsyad Muhammad Sajjad  , Muhammad Widda Djuhan
Published: January 2022

This research was motivated by the low responsibility of students due to the assignments given by the teacher at SMP Negeri 1 Mlarak. Therefore it is necessary to implement learning strategies that are simple and fun for students so that they can instill an attitude of student responsibility. The purpose of this study was to determine the increase in student responsibility attitudes through five steps in the Joyful Learning strategy. This qualitative research carried out three techniques in data collection with interview, observation and documentation techniques. The subjects of this study were social studies teachers and students at SMP Negeri 1 Mlarak. The instruments used were interview sheets, observation and documentation of student responsibility attitudes. The results showed that the joyful learning strategy in cultivating students' responsibility towards assignments had increased, namely first, completing assignments well and on time. Second, enthusiastic and eager to accept the assignment given by the teacher.
Joey e sua mecânica do “corpo”: um olhar sobre a escolha do sujeito autista de se alienar parcialmente à linguagem
Authors: Silva Elisangela Maria da
Published: January 2022

O objetivo do presente estudo é discutir a escolha do sujeito autista: a de se alienar parcialmente ao Outro, partindo das contribuições teóricas de Maleval no tocante ao autista não deixar de manter um domínio sobre o objeto a, seja por retenção ou pela construção de borda. Metodologicamente, realizamos uma discussão teórica sobre as defesas autísticas como proteção da angústia. Numa tentativa de abordar empiricamente o objetivo proposto, recorremos, a título de exemplificação, a recortes do caso Joey de Bruno Bettelheim.
Adverse Obstetric and Perinatal Outcomes in 2333 Singleton Pregnancies Conceived After Different Endometrial Preparation Protocols: a Retrospective Study in China
Authors: Yang Zexin , Bai Xuelian , Han Ying , Zou Zhangxiang , Fan Yazhen , Wang Xinyan , Luo Haining , Zhang Yunshan
Published: January 2022

Background: Frozen-thawed embryo transfer is rising worldwide. One adverse effect of programmed frozen embryo transfer (FET) reported in some studies is an increased risk of adverse obstetric and perinatal outcomes. Meanwhile, body mass index (BMI) also has adverse effect on obstetric and perinatal outcomes. In this study, we investigated that the influence of different endometrial preparation protocols on obstetric and perinatal outcomes and the role of BMI in it.Method: This retrospective study included 2333 singleton deliveries after frozen-thaw embryo transfer at our centre between 2014 and 2021, including 550 cycles with programmed FET, 1783 cycles with true natural cycle FET (tNC-FET). In further analysis according to BMI grouped by Asian criterion, group A (18.5kg/m2≤BMI<24.00kg/m2) included 1257 subjects, group B (24kg/m2≤BMI<28.00kg/m2) included 503 subjects and group C (BMI≥28 kg/m2) included 573 subjects. Baseline characteristics of the two groups were compared and analyzed. Binary logistic regression analyses were performed to explore the association between obstetric and perinatal outcomes and endometrial preparation protocols.Results: There were no significant differences in the placenta previa, gestational diabetes mellitus(GDM), preterm premature rupture of membranes (PPROM), cesarean section (CS) and macrosomia between the tNC-FET and programmed FET groups (P>0.05). The risk of hypertensive disorders in pregnancy (HDP) was increased in programmed FET group compared with the tNC-FET group (7.3% vs 4.4%, crude OR 1.714[1.156-2.542]; adjusted OR 1.845[1.031-3.300]). After dividing the patients into three groups according to the BMI, the risk of HDP in group C (14.4% vs 6.2%，crude OR 2.545 [1.424-4.548]; adjusted OR 4.712 [1.769-12.547]) was increased in programmed FET group compared with the tNC-FET group. But there was no statistically significant difference in group A and group B. Programmed FET group compared with the tNC-FET group, the risk of HDP increase as the body mass index increase.Conclusion: This study showed a tendency toward increasing risk of HDP in programmed FET cycle compared with the tNC-FET cycle, and the risk of HPD increases as BMI increases. Increased risk of preterm birth and low birth weight is linked to increased risk of HPD.
The Effect of Mildly Stimulated Cycle Versus Artificial Cycle On Pregnancy Outcomes In Overweight/Obese Women With PCOS Prior To Frozen Embryo Transfer: A Retrospective Cohort Study
Authors: Guan Lu , Xiang Shan , Wu Haicui , Wei Chaofeng , Pang Conghui , Liu Danqi , Yu Xiaona , Lian Fang
Published: January 2022

Background: Previous studies have shown that frozen embryo transfer (FET) resulted in increased live birth rates (LBR) and reduced the risk of ovarian hyperstimulation syndrome (OHSS) than did fresh embryo transfer in women with polycystic ovary syndrome (PCOS). In addition, overweight/obese women with PCOS are at increased risk of subfertility and complications of pregnancy, compared with normal-weight women. The ovarian stimulation and artificial hormone regimes are the two more commonly used endometrial preparation protocols in PCOS patients.This retrospective study aims to compare the pregnancy outcomes of mildly stimulated cycles (mSTC) and artificial cycles (AC) prior to FET in overweight/obese women with PCOS. Methods: A retrospective analysis was conducted in overweight/obese women with PCOS who underwent their first FET cycles from January 2018 to December 2020. Two endometrial preparation protocols were used: the mildly stimulated cycles (N=173) and the artificial cycles (N=507). All pregnancy outcomes were analyzed by Student’s t-test, Chi-square (χ2) statistics and multivariable logistic regression analyses.Results: This study enrolled 680 cases of FET cycles. The mSTC group exhibited significantly higher LBR compared with the AC group (49.7% vs. 41.0%; P=0.046), while the rate of miscarriage was significantly lower (6.4% vs. 23.0%; P<0.001). No statistically significant differences were observed in positive pregnancy rate (57.8% vs. 60.0%, P=0.618), clinical pregnancy rate (54.3% vs. 55.6%, P=0.769), and ectopic pregnancy rate (2.1% vs. 3.2%, P=0.860) between two groups. After adjusting for possible confounding factors, multivariate logistic regression analysis also yielded similar results. Conclusions: For overweight/obese women with PCOS, mSTC-FET demonstrated a higher LBR and a lower pregnancy loss rate than that in the AC-FET. When considering the most cost-effective treatment with the least adverse effects on patients, the mSTC for FET endometrial preparation may be considered. To corroborate our findings, additional prospective randomized clinical trials with larger sample sizes are required.
Dual Effect of CB1R Antagonist on Motor and Psychological Behaviors in 6OHDA-Induced Parkinsonism Model: Probable Role of Ih Currents
Authors: Soti Monavareh , Ranjbar Hoda , Kohlmeier Kristi A. , Razavinasab Moazamehosadat , Masoumi-Ardakani Yaser , Shabani Mohammad
Published: January 2022

Based on data from our lab and others, the endocannabinoid system (ECBS) appears to be involved in PD-related processes. Therefore, we compared the motor and non-motor effects of the cannabinoid receptor type 1 (CB1R) WIN 55,212-2 (WIN) and selective antagonist (AM251), on motor and non-motor symptoms (NMS) of PD in a mice model generated by an intracerebroventricular (i.c.v.) injection of 6-hydroxydopamine (6-OHDA). To provide further knowledge about the link of CB1R with hyperpolarization-activated current (Ih), we conducted ex vivo investigations in the ventral tegmental area (VTA). In the current study, pharmacological blockage of CB1R ameliorated explorative behaviors, balance, muscle strength, and passive avoidance memory deficits induced by 6-OHDA, however, anxious, and depressive-like behaviors were heightened. 6-OHDA exposure induced severe alterations in the spontaneous and evoked firing behavior of DA neurons as evidenced by a significant increase in the mean number of spikes and a decrease in half-width, respectively. Interestingly, an increase in the amplitude of the sag voltage and in the amplitude of the steady state Ih currents was seen. WIN exacerbated 6-OHDA-induced actions by further reducing the spike half-width and increasing the firing frequency, as well as increasing sEPSP amplitudes. The effects of 6-OHDA on sag voltage, Ih currents amplitude, and firing frequency were reversed by administration of AM251. These results suggest that ECBs might underlie some of the 6-OHDA-induced electrophysiological alterations in VTA DA neurons in this animal model of PD and antagonist of this receptor could be effective in modulating the devastating effects of 6-OHDA.
A self-developed MyD88 inhibitor across the blood-brain barrier fully reverses acute cerebral ischemia-reperfusion injury
Authors: Li Zeyang , Zhao Minghui , Zhang Xiaoqian , Lu Yiran , Yang Yang , Xie Yalong , Zou Zhimiao , Zhou Liang , Shang Runshi , Zhang Limin , Jiang Fengchao , Du Dunfeng , Zhou Ping
Published: January 2022

Background: The acute ischemia-reperfusion injury that occurs after an ischemic stroke is almost inevitable. In treating ischemic stroke, the prevention and treatment of cerebral ischemia-reperfusion injury (CIRI) is an undeniable difficulty clinically. Despite increasing studies being done on the subject, medicines showing effective neurological improvements after reperfusion is still minimal. This study aims to investigate the effects of a self-developed MyD88 inhibitor (TJ-M2010-5) on CIRI and its mechanism.Methods: The middle cerebral artery occlusion (MCAO) model was used to simulate CIRI in mice. BV-2 cells were cultured for the mechanism study by LPS stimulation in vitro. Neurological deficit score and cerebral infarction volume were studied. Immunofluorescence staining was used to measure neuronal damage and apoptosis in the brain. The anti-inflammation effect of TJ-M2010-5 was evaluated by analyzing the expression of inflammatory cytokines, activation of microglia and infiltration of peripheral myeloid cells. The expression of TLR4/Myd88/NF-κB signaling pathway protein was detected by Simple Western. The concentrations of TJ-M2010-5 in blood and brain were analyzed by LC-MS methods.Results: The cerebral infarction volume decreased in mice treated with TJ-M2010-5, with the most prominent decrease in approximately 80% of the original infarction volume. Moreover, the downregulation of apoptosis and NeuN protein expression in the brain of infarction area further indicated that neuronal damage was alleviated. TJ-M2010-5 treatment also reduced the infiltration ratio of peripheral myeloid cells in the cerebral infarction area and increased the proportion of inactive microglia. The inflammatory cytokines decreased after TJ-M2010-5 treatment in infarction area and supernatant. TJ-M2010-5 downregulated the expression of iNOS and inhibited TLR4/MyD88/NF-κB signaling pathway in vivo and in vitro. In addition, TJ-M2010-5 could freely pass through the blood-brain barrier.Conclusions: TJ-M2010-5 has shown to have an excellent therapeutic effect on CIRI by inhibiting TLR4/Myd88/NF-κB signaling pathway to decrease excessive inflammatory response, showing the potential to change the history that there is no effective medicine for the treatment of CIRI. and also has the potential to be utilized in brain neuroinflammatory diseases.