bluuebunny/crossref_metadata_2025 huggingface dataset:
AI-Assisted Wearable Devices for Promoting Human Health and Strength Using Complex Interval-Valued Picture Fuzzy Soft Relations
Authors: Hatamleh Raed , Al-Husban Abdullah , Zubair Sulima Ahmed Mohammed , Elamin Mawahib , Saeed Maha Mohammed , Abdolmaleki Eisa , Fujita Takaaki , Nordo Giorgio , Khattak Arif Mehmood
Published: January 2025

Wearable technology allows users to monitor and track various fitness-related activities and data, including calories burned, distance traveled, heart rate, and sleep patterns. To choose best app for fitness, here introduced a new innovation in fuzzy algebra named as complex interval valued picture fuzzy soft relations (CIVPFSR) by defining the cartesian product (CP) of two complex interval valued picture fuzzy soft sets (CIVPFSS). Additionally, the many kinds of CIVPFS relations are described, and their outcomes are also mentioned in this article. The CIVPFSS has a complex structure that includes multidimensional variables for membership, abstinence, and non-membership degrees. As a result, this research offers modeling techniques for wearable technology that are based on CIVPFSR. The score function for best human decision making is also formulated in this process. Lastly, a comparison of current structures is done to demonstrate the viability of the suggested work with the conclusion highlighting its potential to significantly advance wearable technology. Additionally, a topological space is developed for CIVPFSR, providing a geometric interpretation of these relations and offering insights into their behavior in multi-dimensional decision spaces. The basic operations, operators, related theorems, and results are discussed. Results concerning the interiors and closures are also addressed.
New Newton Group Iterative Methods for Solving Large-Scale Multi-Objective Constrained Optimization Problems
Authors: Cheng Peng , Sulaiman Jumat , Ghazali Khadizah , Ali Majid Khan Majahar , Xu Ming Ming
Published: January 2025

With the rapid development of big data and artificial intelligence technologies, we are facing increasingly complex data and decision-making problems. Solving large-scale multi-objective constrained optimization problems can help to solve many practical engineering and scientific problems. The weighted and Lagrange multiplier methods are considered to be classical and effective methods for dealing with multiple objectives and constraints, but there are some difficulties in solving the processed unconstrained optimization problems.The Newton method is a commonly used method for solving this type of problem, but it requires a high computational complexity. In order to solve these difficulties, we combine four methods such as the Weighted method, Lagrange multiplier method, Newton's method and Explicit Group Gauss-Seidel iterative method to propose new Newton Group iterative methods such as 2 and 4-point Explicit Group Gauss-Seidel iterative methods namely as Newton-2EGGS and Newton-4EGGS for solving large-scale multi-objective constrained optimization problems. Also, the convergence analysis of the proposed method is presented. To test the superiority of the proposed method by comparing the computational results, the Newton-4EGGS iteration is more efficient than both Newton-2EGGS iterative method and the Newton-Gauss-Seidel iterative method (Newton-GS), especially in terms of the number of iterations and the computational time.
Handling Degeneracy in Multi-objective Transportation Problem: An Efficient Branch-and-Bound Algorithm
Authors: Mezali Zineb , Chergui Mohamed El-Amine
Published: January 2025

In today’s competitive market, practically all models are designed to address transportation problems involving multiple, often conflicting, objectives, such as minimizing transportation cost, minimizing transportation time, maximizing reliability, minimizing environmental impact, maximizing social equity, and minimizing product deterioration. In this respect, this paper proposes a method to optimize a multi-objective transportation problem (MOTP). We developed a branch-and-bound-based algorithm coupled with a classical transportation method to find the non-dominated points in the criteria space, in a finite number of steps. The algorithm utilizes reduced costs of all the criteria cost matrices to define the promising regions that may containnon-dominated points. This algorithm is strengthened by efficient bounds allowing us to prune a large number of nodes in the search tree and hence eliminate many dominated points. Efficient bounds further enhance the algorithm by pruning a large number of search tree nodes and eliminating dominated points. The suggested approach effectively addresses the non-degenerate case as well as the degenerate case, the latter of which, to our knowledge, has not been discussed in prior studies on MOTP. To handle degeneracy, we integrated the improved N-tree method into our approach. The effectiveness of our algorithm was assessed by comparing it to Isermann’s method for the non-degenerate case, where it was noticed that our approach gives better results. Additionally, computational experiments confirmed its efficiency in handling degenerate cases. Two numericalexamples are presented to illustrate the step-by-step application of the proposed method.
More on Ideal Topological Groups
Authors: Alammar Saud M. , Alshumrani Mohammed , Özel Cenap
Published: January 2025

In this article, we define and study the concept of ideal topological groups. We study its relation to topological groups. We present examples that show that ideal topological groups and topological groups are independent concepts. We give a sufficient condition for a topological group to be an ideal topological group as well as we give a sufficient condition for an ideal topologicalgroup to be a topological group. Unlike topological groups, ideal topological groups are not nicely behaved with regard to subgroups. We give an example of a subgroup of an ideal topological group that is not an ideal topological group. We show that every open subgroup of an ideal topological group is also an ideal topological group. Moreover, we investigate I-connectedness of ideal topological groups.
Quasi $\theta(\tau_1,\tau_2)$-continuity for Multifunctions
Authors: Pue-on Prapart , Sama-Ae Areeyuth , Boonpok Chawalit
Published: January 2025

This paper presents new classes of multifunctions called upper quasi $\theta(\tau_1,\tau_2)$-continuousmultifunctions and lower quasi $\theta(\tau_1,\tau_2)$-continuous multifunctions. Furthermore, several characterizations and some properties concerning upper quasi $\theta(\tau_1,\tau_2)$-continuous multifunctions and lower quasi $\theta(\tau_1,\tau_2)$-continuous multifunctions are established.
Almost Weakly $(\tau_1,\tau_2)$-continuous Functions
Authors: Boonpok Chawalit , Sompong Supunnee , Khampakdee Jeeranunt
Published: January 2025

This paper is concerned with the concept of weakly $(\tau_1,\tau_2)$-continuous functions. Furthermore, several characterizations and some properties of almost weakly $(\tau_1,\tau_2)$-continuous functions are investigated.
Fourth Order Functional Differential Equations of Neutral Type: Enhanced Oscillation Theorems
Authors: Muhsin Waed , Almarri Barakah , Jazmati Mohammad S. , Moaaz Osama , Elabbasy Elmetwally M.
Published: January 2025

In this paper, we investigate the oscillatory properties of fourth-order neutral delay differential equation solutions in the canonical situation. To our knowledge, this equation has received minimal research. We prove new improved features and relationships for the solution and the accompanying function. Based on these relationships, oscillation theorems were developed that guarantee oscillation of all solutions to the considered equation. The comparison principle used in our results is one of the most significant methods for investigating the oscillatory behavior of delay differential equations. The findings of our study extend and develop a number of previous findings in the literature.
On r-fuzzy Soft δ-open Sets with Applications in Fuzzy Soft Topological Spaces
Authors: Alshammari Ibtesam , Taha Osama , El-Bably Mostafa , Taha Islam
Published: January 2025

In the present paper, we introduce the notion of r-fuzzy soft δ-open sets in fuzzy soft topological spaces. Furthermore, we define and characterize the notions of fuzzy soft δ-closure (δ-interior) operators. After that, we explore the notions of fuzzy soft δ-continuous (semi-continuous and pre-continuous) functions, which are weaker forms of fuzzy soft continuity. We also study some properties of these functions along with their mutual relationships with the help of some problems. Moreover, we present a decomposition of fuzzy soft semi-continuity. Lastly, as a weaker form of fuzzy soft continuity, we define and study the notions of fuzzy soft almost (weakly) continuous functions. Also, we explore the notion of continuity in a very general setting called fuzzy soft (L, M, N, O)-continuity and introduce a historical justification.
Impulsive Protocols for Scaled Consensus in Edge-Dynamic Multi-Agent Systems
Authors: Donganont Siriluk , Witthayarat Uamporn , Donganont Mana
Published: January 2025

This study addresses the challenge of achieving scaled consensus in multi-agent systems with edge dynamics, a critical aspect for practical applications such as traffic networks and distributed energy systems. Utilizing graph theory, matrix analysis, and Lyapunov stability, we propose impulsive consensus protocols designed for both directed and undirected topologies. Theseprotocols enable agents to converge proportionally to desired ratios among states, generalizing classical consensus approaches while significantly reducing communication and control costs. We establish sufficient conditions for achieving scaled consensus, demonstrating that it requires the line graph of the communication network to be connected and contain a spanning tree. Numerical simulations validate the robustness and efficiency of the proposed protocols, highlighting their scalability and adaptability in dynamic and resource-constrained environments. The findings provide a solid foundation for real-world applications, including autonomous vehicles, distributed energy systems, and robotic coordination, where proportional state alignment is essential.
Variables que influyen en las constantes fisiológicas en bovinos Simmental y Simbrah en el occidente de México
Authors: Torres-Heredia Angelica , Vega-Murillo Vicente Eliezer , Villaseñor-González Fernando , Palacios-Fránquez José Antonio , Martínez-Velázquez Guillermo , Guzmán-Rodríguez Luis Felipe , Flores-López Hugo Ernesto , Montaño-Bermúdez Moisés
Published: January 2025

El estrés calórico es una desventaja para la producción de ganado en el trópico. La temperatura no es el único factor que modifica las constantes fisiológicas. En México, las razas Simmental y Simbrah contribuyen a la producción nacional de carne en diferentes zonas agroecológicas, por lo cual evaluar los factores ambientales que modifican las principales constantes fisiológicas en animales Simmental y Simbrah en el occidente de México es importante. Se utilizaron 341 ejemplares distribuidos en 6 unidades de producción. Con 147 ejemplares pertenecientes a la raza Simmental y 194 a la raza Simbrah machos y hembras con una edad promedio de 18 meses. Se midió la Frecuencia Respiratoria (FR), Frecuencia Cardiaca (FC), Temperatura Rectal (TR) y niveles de ITH en los meses de junio y julio de los años 2018 y 2019. En ambas mediciones (6:00 y 13:00 h.) se presentaron niveles de peligro de ITH. El análisis estadístico de las mediciones de las constantes fisiológicas se llevó a cabo mediante análisis de varianza de medidas repetidas, utilizando PROC MIXED de SAS, versión 9.4. La comparación de medias se realizó con la prueba de comparaciones múltiples de t protegida de Fisher. Los efectos de año y mes presentaron diferencias en las constantes teniendo mayor medición de FC en el año 2018 y mayor medición en la TR y FR en el mes de julio. El efecto de edad e ITH presentaron diferencias estadísticas significativas (p < 0.05) para la TR, FC y FR. Las constantes fisiológicas de los bovinos se ven afectadas por la diferencia de ITH presente en diferentes horarios (6:00 y 13:00 h) asociado a la implementación de mecanismos de termorregulación.
Influencia de los factores biológicos, psicológicos y socioculturales en el cuidado podológico de adultos mayores con diabetes tipo II
Authors: Cortes Montelongo Diana Berenice , Hurtado Sanchez Eduardo , Nuncio Domínguez José Luis , CORTEZ GONZALEZ LUIS CARLOS
Published: January 2025

Resumen
Objetivo: Determinar la influencia de las variables factores personales biológicos (edad, sexo) psicológicos (deterioro cognitivo y estado de salud percibido)y socioculturales (estado civil, escolaridad y nivel socioeconómico), sobre el cuidado podológico de adultos mayores que padecen diabetes tipo II. Metodología: Estudio descriptivo-correlacional predictivo, con una muestra de 100 personas adultas mayores ≥ 60 años, con diabetes tipo 2; se usó un muestreo no probabilístico a conveniencia. Se utilizó una cédula de datos personales, socioculturales (estado civil, escolaridad e ingreso económico). Cuestionario de Pfeiffer, Cuestionario de salud percibida SF-12v2  y Cuestionario de cuidados podológicos en personas con DT2. Se aplicó la prueba de Kolmogorov-Smirnov con corrección de Lilliefors, se utilizó estadística no paramétrica.Las pruebas estadísticas inferenciales que se emplearon fueron el Coeficiente de Correlación de Spearman y Modelo de Regresión Lineal Múltiple.  Resultados Se encontró en las PAM, una valoración cognitiva normal, una mala percepción del estado de salud, el cuidado podológico fue aceptable.  La edad, el estado cognitivo y el ingreso mensual influyen en el cuidado podológico un 31.3%, siendo estadísticamente significativo (F=14.565, p=.000).
ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) AGAINST PEAK EXPIRATORY FLOW IN COPD PATIENTS
Authors: Yuniarti Enny Virda
Published: January 2025

COPD patients often experience the accumulation of secretions in the respiratory tract. To overcome the buildup of secretions in the respiratory tract, the Active Cycle Of Breathing Technique (ACBT) can be applied to the respiratory tract and increase the value of peak expiratory flow. This study aims to determine the effect of active cycle of breathing technique therapy (ACBT) therapy on peak expiratory flow in COPD patients. This research is a Pre-experimental type research that uses a One Group Pretest-Posttest design with the provision of ACBT intervention done 1x on the respondent. Instruments in evaluating lung function lung function of this study using the Peak Flow Meter. The sample in this study amounted to 30 respondents who had been selected through purposive sampling based on inclusion and exclusion criteria by researchers. Data analysis technique data in this study using the Paired T-Test test with the help of the SPSS program. Before being given ACBT intervention, the average value of peak respiration flow was found to be 83.67 lpm and after the ACBT intervention, the average value of peak flow of respiration was found to be 185.00 lpm. The results of statistical test analysis using Paired T-test obtained the results of p-value obtained 0.000 < α0.05 then there is a difference in the average value of peak expiratory flow before and after ACBT in patients with Chronic Obstructive Pulmonary Disease. This study concludes that there is a significant effect of the application of the Active Cycle of Breathing Technique (ACBT) intervention on the value of peak respiration flow in COPD patients.
Gamificación en la educación de negocios y finanzas: Impacto de juegos digitales en el aprendizaje
Authors: Bermejo Rodríguez Gabriela Alejandra
Published: January 2025

Este trabajo analiza el impacto de la gamificación en la educación de negocios, con énfasis en conceptos clave, motivación y compromiso en Finanzas. Se realizó un estudio cuantitativo descriptivo-correlacional con 64 estudiantes de quinto semestre de la Preparatoria Tec, campus Eugenio Garza Lagüera, en Monterrey, Nuevo León. Los participantes, entre 17 y 19 años, cursaron previamente Gestión Empresarial y participaron en actividades gamificadas durante el semestre iniciado en agosto de 2024. Un cuestionario basado en literatura previa evaluó motivación, compromiso y comprensión. Los resultados muestran que la gamificación mejora significativamente estos aspectos, destacando su utilidad como estrategia educativa en la formación de futuros profesionales de negocios.
Academic strategy for teachers of engineering to obtain a B2 English proficiency certification
Authors: López-Cuéllar Enrique , Arroyo Reyna Edgar Fernando , Aguilar-Garib Juan Antonio , Treviño-Cubero Arnulfo
Published: January 2025

This paper describes an academic strategy for Mexican university teachers of engineering aiming to obtain the B2 Cambridge FCE (called First Certificate in English). Its goal was formative, focusing on distinguishing language knowledge from the skills for the exam. Teachers identified at B1 level enrolled in a training course with exercises resembling the FCE exam, helping them assess their current level, build confidence, and adapt to exam conditions especially time constraints. About 87% of participants who completed the process achieved their B2 certification, showing that training professors who had certain level of English could level it up and reach the certification mostly in the target level. The strategy described in this article could be considered by other institutions to get professors to obtain a certification worldwide recognized of their proficiency in English.
INVESTIGATION OF A COMPACT MICROSTRIP PATCH ANTENNA FOR WIRELESS COMMUNICATIONS
Authors: Dubey Poornanand
Published: January 2025

Indicates the comparative characterization of a microstrip patch antenna array with defective geostructure for biomedical application. Compared to traditional antennas, various antennas have advantages in terms of small dimension, low volume, light weight, ease of construction, as well as low interference and good performance after which all understudies use mobile phones to go to classes and educators to take web classes use cell phones. For the above use we need a fast 5G organization with high Bandwidth. This paper proposes a reduced 5G Microstrip patch antenna with DGS structure for better approach for 5G wireless applications. The DGS idea is widely used to improve the radiation properties of the reception device. In the proposed work, a 5G Microstrip patch antenna with 0.4mm thickness FR4 substrate and Dielectric constant (฀r) of 4.4 is planned.
Leveraging LangGraph and AutoGen for Agentic AI Frameworks
Authors: Gaurav Samdani  , Yawal Dixit  , Ganesh Viswanathan
Published: January 2025

This research examines how LangGraph and AutoGen improve Agentic AI models by enabling improved autonomous functioning in dynamic environments. Researchers examine LangGraph's language-based system and AutoGen's generative model as independently working tools for agent autonomous performance in intricate situations. Our study uses quality-benchmarking data and test simulations to examine modeling effects on AI agents' behavior and decision-making. The study shows that LangGraph boosts language understanding effectiveness while AutoGen improves the system's ability to adjust decisions swiftly in real-time. Our conclusion points to combined advancements enabling us to develop smarter AI systems that can operate autonomously under unpredictable real-world conditions.
A prospective study of antibiotic susceptibility pattern of uropathogens in a tertiary care hospital
Authors: Andrea Assuez  , Amrutha Murali  , Athul K Rajan  , Cijo George  , Chitra C Nair  , Beena P
Published: January 2025

Background: Urinary tract infection (UTI) is a frequent condition encountered in primary care. Treatment is usually empirical without urine culture and susceptibility testing because the causative uropathogens and their antimicrobial susceptibility profiles are considered to be predictable. However, there is increasing evidence of antimicrobial resistance in community- acquired uropathogens. This study aimed to assess the prevalence and antimicrobial susceptibility pattern of uropathogens causing UTI.

Methods: A prospective study was conducted over a period of six months in a tertiary care hospital in Kerala, India. A total of 100 patient case records satisfying the inclusion criteria were analysed to determine the prevalence of uropathogens causing UTI and also to determine antibiotic sensitivity pattern of uropathogens to various antibiotics. All the relevant and necessary data of the patient were collected from patient’s case record and microbiology department to study the rational prescribing of antibiotics before and after culture sensitivity test. Data analysis was conducted using Chi-squared test and descriptive statistics.

Result: In this study, we observed a higher incidence of UTIs in females, particularly among individuals aged over 70 years. The primary microorganisms isolated from these cases were Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Upon conducting culture sensitivity tests, approximately half of the initially prescribed antibiotics were altered. Penicillin class of antibiotic was frequently substituted, predominantly with drugs from the carbapenem class. Our analysis of antibiotic sensitivity revealed that Imipenem exhibited the highest sensitivity, followed by meropenem and colistin within our study cohort.

Furthermore, a chi-square test was conducted, yielding a chi-square value of 12.25 with a p-value less than 0.001, implies that there is a significant difference between drugs given before and after C/S was done. These findings underscore the importance of tailored antibiotic selection based on microbial sensitivity profiles, especially in elderly female patients, to ensure effective treatment outcomes for UTIs.

Conclusions: According to the research, UTIs are the most common public health issue, primarily affecting women. Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosawere the most common isolated organisms in our study that caused UTIs in IndiaMost isolates exhibited resistance to widely used antibiotics.Thus, regular surveillance and monitoring are essential for improved patient care.
Adaptation of the Quality of Sibling Experience Scale for Individuals with Special Needs Siblings into Turkish: A Methodological Study
Authors: Ozdemir Tugba , Karadağ Gülendam , Bektaş Murat
Published: January 2025

Purpose: The relationship between siblings, which is a lifelong bond, affects both the individual with special needs and their healthy sibling in many ways. This study was conducted to do the Turkish validity and reliability study of the Siblings’ Experience Quality Scale (SEQS).
Material and Methods: The study was carried out with individuals who were aged over 18 and had a sibling enrolled in the Guidance and Research Center of a province. Shapiro-Wilk normality test, Pearson correlation analysis, content validity index, Cronbach’s Alpha coefficient, McDonald’s omega test, confirmatory factor analysis, and t-test were used in data analysis.
Results: The healthy siblings of 171 students with special needs voluntarily participated in the study. The scale explained 54.8% of the total variance. The omega reliability coefficient value for the overall scale was determined as 0.81. As a result of CFA, the fit indices were found as X2=247.893, df=128, X2/df=1.93, RMSEA=0.074, GFI=0.86, IFI=0.85, NFI=0.73, TLI=0.81, CFI=0.84, and AGFI=0.819.
Conclusion: The SEQS was proven to be a valid and reliable measurement tool in the Turkish population
The Relationship Between Anticipatory Nausea and Vomiting with Social Support and Anxiety in Cancer Patients Undergoing Chemotherapy
Authors: Yaşa Yağmur , Karadağ Ezgi
Published: January 2025

Abstract
Purpose: This study aims to investigate the relationship between anticipatory nausea and vomiting in
cancer patients undergoing chemotherapy with social support and anxiety.
Material and Methods: This descriptive-correlational study involved 134 cancer patients receiving
chemotherapy at a university hospital and experiencing anticipatory nausea. Anxiety levels were
measured using the Beck Anxiety Inventory (BAI), while the severity of nausea was assessed using
the Visual Analog Scale (VAS-nausea), and social support levels were evaluated using the Cancer
Patient Social Support Scale (CPSSS). Descriptive statistics were employed to analyze demographic
characteristics. Independent sample t-tests, Kruskal-Wallis, one-way analysis of variance (ANOVA),
Mann-Whitney U test, Cronbach's alpha coefficient, and Pearson correlation analysis were used for
data analysis.
Results: Results showed that 62.7% experienced moderate to severe nausea post-chemotherapy,
with 57.5% having received prior chemotherapy. 61.2% reported minimal anxiety. Patients under
moderately emetogenic treatments exhibited higher anticipatory nausea scores. Anxiety inversely
correlated with social support, but no significant link was found between anticipatory nausea severity
and anxiety/social support levels.
Conclusion: The findings indicate that there is no relationship between anticipatory nausea and
vomiting, social support, and anxiety among cancer patients undergoing chemotherapy.
Examination Of The Relationship Between Body Mass Index And The Skin-Epidural Space Distance Measured By Ultrasound In The Lumbar Region
Authors: Kaytancı Damla , Küçükgüçlü Semih , Büyükçoban Sibel , Şimşek Muhammet Kürşat , Barış Mustafa Mahmut , Ellidokuz Hülya
Published: January 2025

The aim of the study; to investigate whether there is a relationship between body mass index (BMI), waist circumference, and abdominal subcutaneous adipose tissue and the skin-epidural space distance measured by ultrasonography.
Healthcare Professionals' Knowledge Level Regarding Forensic Cases in The Intensive Care and Operating Room
Authors: Özkan Esra , Sürmeli Şeyma , Albayrak Tuna
Published: January 2025

Purpose: Forensic cases are encountered in not only emergency units but also operating rooms, and intensive care units. It is believed that increasing the level of knowledge about forensic cases in these areas will improve the quality of healthcare services. This plays an important role in fulfilling ıntensive care professional responsibilities and contributes to the legal process. This study aims to assess the knowledge and practices of healthcare professionals in operating rooms and intensive care units regarding forensic cases.

Material and Methods: A descriptive comparative design study was conducted, involving healthcare professionals from a university hospital in the Eastern Black Sea Region between March 17 and May 1, 2023 (n=116). Data were collected through a questionnaire developed by the researchers, and analysis was performed using descriptive statistics, t-tests, variance analysis, and correlation analysis.

Results: Participants had a mean age of 30.6±7.7 years, with 56% working in operating rooms and 56.9% being nurses. While 53.4% had received training on forensic cases, 82.8% had encountered such cases. Education significantly influenced both knowledge level (p=0.00) and application (p=0.02), with a moderate positive correlation between knowledge and application (r=0.541, p=0.000).

Conclusion: The study highlights a lack of knowledge and practices among healthcare professionals in operating rooms and intensive care units regarding forensic cases. It recommends providing detailed and regular training on forensic events and suggests further research with a larger sample size to address this issue comprehensively.
Differential Effects of Sertraline and Penfluridol on EMT and ECM Remodeling in Glioblastoma Cell Lines
Authors: Keleş Bartık Didem , Sipahi Murat , İnanç-sürer Şeniz , Oktay Gülgün
Published: January 2025

Background and Purpose: Glioblastoma multiforme (GBM) is an aggressive brain tumor with poor prognosis due to rapid recurrence, chemoresistance, and limited efficacy of standard therapies. Epithelial-to-mesenchymal transition (EMT) and matrix metalloproteinase (MMP)-mediated extracellular matrix (ECM) remodeling are critical processes in GBM progression and metastasis. The aim of this study is to examine the potential effects of sertraline and penfluridol on the EMT process and gelatinase activity in human glioblastoma cell lines.
Methods: U87 and U251 human glioblastoma cells were treated with sertraline and penfluridol at previously identified IC50 doses. Protein levels of EMT markers, E-cadherin, vimentin, Snail, Slug, Twist1, phospho-Akt (p-Akt), and tissue inhibitor of metalloproteinases-2 (TIMP-2), were evaluated using Western blotting. Additionally, the impact of sertraline and penfluridol on the release and activity of MMP-2 and MMP-9 were assessed through gelatin zymography.
Results: Both sertraline and penfluridol significantly reduced vimentin expression in U251 cells, indicating inhibition of the mesenchymal phenotype. Conversely, these drugs increased vimentin levels in U87 cells, highlighting cell line-specific differences. Sertraline and penfluridol also increased TIMP-2 levels in U251 cells but not in U87 cells. Neither drug altered MMP-2 or MMP-9 activity in either cell line, suggesting that their effects on ECM remodeling may be mediated through TIMP-2 upregulation rather than direct modulation of gelatinase activity.
Conclusion: These findings suggest that sertraline and penfluridol potentially inhibit EMT and reduce ECM degradation in U251 cells but exert contrasting effects in U87 cells. This highlights the heterogeneity of GBM tumors and the importance of personalized therapeutic approaches.
THE INFLUENCE OF CUSTOMER INCIVILITY ON HOTEL FRONTLINE EMPLOYEES' RESPONSES AND SERVICE SABOTAGE: DOES CO-WORKER SUPPORT MATTER?
Authors:   Higher Institute for Specific Studies, Hotel Management Department, Heliopolis, Cairo, Egypt, e-mail: mohamadfathy.eg@gmail.com, AGINA Mohamed Fathy , FARRAG Dalia Abdelrahman ,   Qatar University, Management and Marketing Department, College of Business & Economics, Doha, Qatar, e-mail: dfarrag@qu.edu.qa, JABER Humoud Mohamed ,   King Khalid University, Tourism Department, College of Tourism and Hospitality, Abha, Saudi Arabia, e-mail: hjaber@kku.edu.sa, FAYYAD Sameh ,   Suez Canal University, Hotel Studies Department, Faculty of Tourism and Hotels, Ismailia, Egypt, e-mail: sameh.fayyad@tourism.suez.edu.eg, ABBAS Tamer M. ,   King Salman International University, Faculty of Tourism and Hospitality, Cairo, Egypt, e-mail: Tamer.abbas@ksiu.edu.eg, SALAMEH Anas A. ,   Prince Sattam bin Abdulaziz University, Department of Management Information Systems, College of Business Administration, Al-Kharj, Saudi Arabia, e-mail: a.salameh@psau.edu.sa, ELZINY Mohammed N. ,   Helwan University, Hotel Management Department, Faculty of Tourism and Hotel Management, Cairo, Egypt, e-mail: MOHAMED.NAGY@fth.helwan.edu.eg
Published: January 2025

Customer incivility poses a difficulty for service industries since employees' negative responses to such customers
may threaten the organization's success. Service industries implement stringent display guidelines and keep an eye on how
Frontline Employees' Responses (FLEs) engage with customers. This study aims to investigate the impact of customer
incivility on FLEs' negative responses and service sabotage, and to evaluate the moderating effect of co-worker support. The
data is collected from 386 Sharm El-Sheikh hotel employees. The PLS-SEM results revealed that customer incivility
positively affects service sabotage, FLEs rumination, and retaliation intention. Similarly, the study findings proved that FLEs'
rumination and retaliation intention positively affect service sabotage behavior. Accordingly, both FLEs' rumination and
retaliation intention, based on the results, succeeded in mediating the linkage between customer incivility and service
sabotage behavior. In addition, the current study strived to use co-worker support as a strategy to mitigate customer incivility
consequences by investigating its influence as a moderator on the relationships of customer incivility towards both FLEs'
rumination and retaliation intention, and the result demonstrated that co-worker support succeeded in mitigating the customer
incivility negative impacts. The study's results broaden our understanding of the effect of customer incivility on two different
types of employee responses (psychological and behavioral). The practical contributions recommend the need to train FLEs to
give them sufficient experience and skills to deal with customer incivility behaviors, and mutual support behaviors must be
developed among workers.
Human Biofield Components Explained: A Tensegrity-Based Biophysical Framework for Energy Medicine.
Authors: Sá Rick
Published: January 2025

This review explores how electric, magnetic and biophysical fields interact with biological structures such as tissues, cells and DNA. Furthermore, it is suggested that these interactions create an integrated system of internal communication, with potential to promote therapeutic benefits. The Biofield-Tissue Tensegrity Matrix (BTTM) model is suggested by combining concepts from physics, biology and medicine to explain how energy therapies, such as biofield therapies, can influence biological processes. Finally, it is proposed that this model may offer new scientific avenues for traditional medical practices and help to develop therapeutic approaches for diseases in energy medicine.
CHOAMs are All You Need: Using Urban Chains of Activities to Uncover the Interplay Between Mobility, Diversity, and Value
Authors: Baciu Dan Costa
Published: January 2025

This article explores the complex relationship between mobility, diversity, and perceived urban value by studying urban “chains of activities” that define city life. Introducing chains-of-activities-models (CHOAMs), we present a method for systematically analyzing how individuals move through the city and engage in a variety of urban activities. We also show that changing mobility options or the supply of activities can directly influence the ways people experience and the extent to which they value the urban environment. By facilitating rapid modeling and testing of scenarios, our research framework empowers urban planners, designers, and policymakers to envision cities as dynamic systems and leverage the relationship between mobility and diversity to optimize human-scale benefits. Through these insights obtainable through CHOAMs, the present article opens the door to a future of automated, proactive, and value-driven urban design.
CHOAMs are All You Need: Using Urban Chains of Activities to Uncover the Relationship Between Mobility, Diversity, and Value
Authors: Baciu Dan Costa
Published: January 2025

This article explores the complex relationship between mobility, diversity, and perceived urban value by studying urban “chains of activities” that define city life. Introducing chains-of-activities-models (CHOAMs), we present a method for systematically analyzing how individuals move through the city and engage in a variety of urban activities. We also show that changing mobility options or the supply of activities can directly influence the ways people experience and the extent to which they value the urban environment. By facilitating rapid modeling and testing of scenarios, our research framework empowers urban planners, designers, and policymakers to envision cities as dynamic systems and leverage the relationship between mobility and diversity to optimize human-scale benefits. Through these insights obtainable through CHOAMs, the present article opens the door to a future of automated, proactive, and value-driven urban design.
Comparing color qualia structures through a novel similarity task in young children versus adults
Authors: Moriguchi Yusuke , Watanabe Ryoichi , Sakata Chifumi , Zeleznikow-Johnston Ariel , Wang Jue , Saji Noburo , Tsuchiya Naotsugu
Published: January 2025

Examination of the subjective qualitative aspects of an experience, or ‘qualia’ in short, is a fundamental and core aspect of consciousness research. How can we characterize the particular quality of redness or a red quale? Based on a recent proposal of the structural characterization of qualia, which did not rely on verbal descriptions, we developed a task that obtained pairwise similarity judgments at four graded levels, with easy and intuitive visual interfaces designed to engage young children. We examined color qualia structures in children (3–12-year-old in Japan and 6–8-year-old in China) and compared these with those of Japanese adults. Approximately half of the assessed 3-year-old children completed the experiment via our touch panel device version of the task and had reliable responses. Despite known developmental and/or cultural effects of color term usage, we found that color qualia structures were quite similar across the age groups and cultures. Our finding supports the view that color qualia structures emerge early. We also observed age-related differences in the evaluations of some color pairs, which implied subtle changes in the structures behind color experience.
Towards a transition to renewable energy sources in Central Asian countries
Authors: Bayarkhuu T. , Belov V. I.
Published: January 2025

The article discusses the main approaches to implementing the transition to renewable energy sources in the countries of Central Asia. The authors analyze the current situation with the use of traditional energy sources, as well as the advantages and prospects for using renewable resources. The article highlights the main problems and challenges associated with the transition to renewable sources, such as lack of funding, lack of necessary infrastructure and technology, etc. The advantages of using solar, wind and hydropower in the context of sustainable development, environmental security and energy inde5pendence are discussed. In conclusion, recommendations are offered for the successful implementation of energy policy based on renewable sources in Central Asia. The article is of interest to researchers, politicians, business representatives and anyone interested in energy and sustainable development in the Central Asian region.
Kinetic characterization of parsley drying (petroselinum sativum var. Latifolium)
Authors: Hernández Fernández Yaisely Orquídea
Published: January 2025

The study addresses the characterization of two parsley drying technologies. To this end, two seasoning dehydration procedures were compared: the artificial method in an oven at 40 °C and an average relative moistureof 50% and natural drying in trays with a metal mesh bottom arranged on cemented plates. The kinetic characterization of both procedures was carried out by fitting three mathematical models. The determination of quality was carried out according to the determinations of: moisture content, appearance and water activity. The results provide the productive base with the technical elements that can be decisive for the selection of artificial or natural technology for the dehydration of this highly perishable condiment species. It was demonstrated that the thermal gradient generated in the artificial technology caused greater dynamics of moisture extraction and better colorimetric quality in the seasoning compared to what was obtained in the natural process.
Traditional Medicine in The Developing and Developed Countries and Expected Trends in Future
Authors: Haider Rehan
Published: January 2025

Traditional Medicine has been practiced all through the whilst in almost all countries, imparting increased health care. Traditional drugs have also been used for this purpose.locally accessible plant, animal, and mineral supplies and proceed to supply healthcare for humans, in several developing countries. Traditional Medicine (TM) has developed over time and continues to be the primary health service of rural communities and the poorest stage of society. Presently there is a developing reliance on regular health care using city populations.WHO defines frequent treatment as “diverse health practices, approaches, knowledge and beliefs incorporating plant animal and/ or mineral-based medicines, spiritual therapies, information techniques, and exercising routines utilized singularly or in combination to keep well-being as appropriate as to treat, diagnose or prevent illness” In Asia, there are formalized traditions/systems which have theoretical frameworks. With hooked-up traditions of training, formalized educational processes, recorded materia medica with many preparations, and scientific practices with a variety of preventative and therapeutic modalities, such as Traditional Chinese Medicine, Ayurvedic Medicine, Traditional Vietnamese Medicine, Unani, and Siddha.
DNA and RNA Applications and Roles in Forensic Science
Authors: Heidari Alireza
Published: January 2025

The paper affords the consequences of a list of questions survey carried out with the aid of The (extremely cautious, crime-solving, technological know-how-based) laboratory of the country wide Bureau of (act of asking questions and trying to find the fact about something) (NBI-FL), aiming to get a precis of the modern-day reputation of (related to surrounding conditions or the health of the Earth) (extraordinarily careful, crime-solving, technological know-how-based totally) technology (EFS) and (related to surrounding situations or the health of the Earth) crimes (act of asking questions and trying to find the fact approximately something) inside the (associated with Europe) network.
Transforming Glomerulonephritis Care Through Emerging Diagnostics and Therapeutics
Authors: A. Addissouky Tamer
Published: January 2025

Background: Glomerulonephritis refers to a range of conditions involving inflammation and injury to the kidneys' glomeruli, often leading to significant morbidity if left untreated.

Purpose: This review aims to examine emerging advancements in the prevention and treatment of glomerulonephritis, and highlight progress in transforming the prognosis of this spectrum of diseases, while also identifying gaps requiring ongoing effort.

Main body: Novel targeted immunotherapies utilizing engineered delivery platforms and biologicals like monoclonal antibodies are progressing in research pipelines, potentially offering safer, more efficacious alternatives to current standard immunosuppression. High-throughput biomarker assays and AI/machine learning algorithms have demonstrated the ability to improve early detection of kidney damage and guide personalized treatment plans. Further prevention opportunities emerge from modulating microbiome-immune interactions, lifestyle factors, and vaccinations shielding against infections triggering renal disorders.

Conclusion: Although challenges remain, recent advancements in unraveling the pathogenesis of glomerulonephritis coupled with the emergence of cutting-edge diagnostics and targeted interventions set the stage for a new era combating the risk and progression of this spectrum of diseases.
A Comprehensive Review of the Pathological Mechanism of Evans Syndrome
Authors: Asadi Shahin
Published: January 2025

Evans syndrome is a rare disease in which the immune system produces antibodies that mistakenly destroy red blood cells, platelets, and sometimes some white blood cells called neutrophils. This leads to abnormally low levels of these blood cells in the body (cytopenia). The premature destruction of red blood cells (hemolysis) is known as autoimmune hemolytic anemia, or AIHA. The symptoms and severity of Evans syndrome can be very different from person to person, as can the onset, course and duration of this disorder. Most people show a chronic course with periods of worsening of symptoms (exacerbation) and usually transient improvement with treatment. Most symptoms are caused by low levels of certain blood cells in the body. The exact cause of Evans syndrome is unknown. Evans syndrome is an autoimmune disease. It occurs when the immune system produces antibodies that mistakenly attack healthy tissue, particularly red blood cells, platelets, and sometimes some white blood cells.
Cuerpo, memoria y emociones: el dominio masculino en los mazahuas de San Felipe del Progreso, México
Authors:   Universidad Intercultural del Estado de México, Gómez Sánchez David , Bruno Rosas Sonia Liliana ,   Universidad Intercultural del Estado de México
Published: January 2025

En el contexto actual, las sociedades indígenas de México enfrentan una constante interacción
con las dinámicas de un mundo globalizado. Sin embargo, muchas de estas comunidades
preservan características endógenas que perpetúan sus normas y comportamientos
tradicionales. Este estudio se enfoca en la cultura mazahua, específicamente en el municipio
de San Felipe del Progreso, Estado de México, para analizar cómo el dominio masculino
continúa configurándose como una forma de vida aceptada y naturalizada. Desde una
perspectiva etnográfica, exploramos no solo las experiencias de hombres y mujeres en relación
con los roles de género, sino también las vivencias de personas con orientaciones sexuales
diversas. Asimismo, contextualizamos prácticas disciplinarias, como el uso de “la calilla”, y
sus implicaciones en la educación y socialización mazahua. Los resultados evidencian que
el dominio masculino se inscribe como memoria en el cuerpo y las emociones, moldeando
el modo de vida y la concepción de la propia identidad desde edades tempranas. Esto
refuerza jerarquías sociales y roles de género, perpetuando un sistema de poder que afecta
profundamente las relaciones familiares y comunitarias
Uncertain Relations
Authors: Strathern Marilyn
Published: January 2025

In 2023, the SIEF convenors set out the multivalent character of “uncertainty” as at once opening up terrains riddled by catastrophe, reminding us of a quality of everyday being, while also promising alternative paths and possibilities. This talk, presented in Brno as the Congress Keynote, offered one way to engage with this complex field. It proposed to interrogate the notion of uncertainty through another multivalent notion, “relations”. Might our ability to perceive relations – activate them, embody them, and enquire with them – help us acknowledge the role that uncertainty plays in our lives? Might thinking of relations as uncertain in their capacities and effects throw light on what we ask from knowledge practices in order to enlarge and/or shrink the world in which we live? From global crises to fieldwork encounters, presenting certain ways of thinking uncertainty through relations hoped to sketch something of the broader themes of that Congress.
Hitchhacking, Passenger Ethnography, and Four-Wheeled Hospitality
Authors: Martínez Francisco , Laviolette Patrick
Published: January 2025

This article proposes hitchhacking as a way of problematising contemporary mobility and as a practice of what we call “passenger ethnography”. To this end, we review some of the literature on hitchhiking and hosting, offering empirical examples from artistic projects and field vignettes in Estonia, Russia, and Finland. We also reflect on how hitching can be experienced as a means of knowledge production. Accordingly, we discuss how travelling together by car provides a particular type of socialisation. Finally, we refer to hitchhiking as a form of gift-giving in which no direct reciprocation is required. The article's key contributions are thus threefold: (1) to rethink the transgressive and heuristic potential of hitchhiking in the present; (2) to reflect on the methodological implications of doing ethnographic research on/in vehicles; and (3) to reconsider mobility disruptions in a context of extensive digital technology usage and novel forms of datafication and accountability.