bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S3 from The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment
Authors: Qian Yanyan , Yuan Jupeng , Hu Huili , Yang Qifeng , Li Jisheng , Zhang Shuqian , Jiang Baichun , Shao Changshun , Gong Yaoqin
Published: March 2023

Supplementary Figure S3. Increased generation and impaired maturation of CD11b+Gr-1+ cells in naïve Cul4b CKO mice.
Supplementary Figure S1 from The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment
Authors: Qian Yanyan , Yuan Jupeng , Hu Huili , Yang Qifeng , Li Jisheng , Zhang Shuqian , Jiang Baichun , Shao Changshun , Gong Yaoqin
Published: March 2023

Supplementary Figure S1. Lack of CUL4B in hematopoietic system promotes the growth of tumor grafts and the accumulation of MDSCs.
Supplementary Figure 4 from Suppression of Intratumoral CCL22 by Type I Interferon Inhibits Migration of Regulatory T Cells and Blocks Cancer Progression
Authors: Anz David , Rapp Moritz , Eiber Stephan , Koelzer Viktor H. , Thaler Raffael , Haubner Sascha , Knott Max , Nagel Sarah , Golic Michaela , Wiedemann Gabriela M. , Bauernfeind Franz , Wurzenberger Cornelia , Hornung Veit , Scholz Christoph , Mayr Doris , Rothenfusser Simon , Endres Stefan , Bourquin Carole
Published: March 2023

Supplementary Figure 4-Inducible secretion of CCL22 by CT26-CCL22dox cells.
Supplemental Figure S5 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: March 2023

Supplemental Figure S5. Akti-treated murine CD8+ T cells have enhanced expression of "naïve/memory"-associated genes (e.g. Klf2, Tcf7, Lef1, Foxo1, and Sell) and decreased expression of "effector"-associated genes (e.g. Eomes, Prf1, GzmB, and Klrg1).
Supplemental Figure S4 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: March 2023

Supplemental Figure S4. Akti-treated tumor-specific Pmel CD8+ T cell have reduced phosphorylation of Akt and substrates in presence of pharmacologic inhibition of Akt.
Supplementary Material and Figure Legends from Immuno-PET Imaging of Engineered Human T Cells in Tumors
Authors: Mall Sabine , Yusufi Nahid , Wagner Ricarda , Klar Richard , Bianchi Henrique , Steiger Katja , Straub Melanie , Audehm Stefan , Laitinen Iina , Aichler Michaela , Peschel Christian , Ziegler Sibylle , Mustafa Mona , Schwaiger Markus , D'Alessandria Calogero , Krackhardt Angela M.
Published: March 2023

Supplementary Material and Figure Legends
Supplementary Table S9 from PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells
Authors: Rahme Gilbert J. , Zhang Zhonghua , Young Alison L. , Cheng Chao , Bivona Eric J. , Fiering Steven N. , Hitoshi Yasuyuki , Israel Mark A.
Published: March 2023

Primers used for genotyping.
Supplementary Table 2 from Copy Number Alterations in Enzyme-Coding and Cancer-Causing Genes Reprogram Tumor Metabolism
Authors: Sharma Ashwini Kumar , Eils Roland , König Rainer
Published: March 2023

iMetCG calculated statistics for all cancer types.
Supplementary Table S1 from PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells
Authors: Rahme Gilbert J. , Zhang Zhonghua , Young Alison L. , Cheng Chao , Bivona Eric J. , Fiering Steven N. , Hitoshi Yasuyuki , Israel Mark A.
Published: March 2023

Antibodies used and dilutions.
Supplementary Figure Legends from NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells
Authors: Joo Jung Hee , Oh Hyunjin , Kim Myungjin , An Eun Jung , Kim Rae-Kwon , Lee So-Young , Kang Dong Hoon , Kang Sang Won , Keun Park Cheol , Kim Hoguen , Lee Su-Jae , Lee Daekee , Seol Jae Hong , Bae Yun Soo
Published: March 2023

Supplementary Figure S1: Interaction between NoxO1 and Grb2 Supplementary Figure S2: Interaction domains between NoxO1 and Grb2 Supplementary Figure S3: Stability of Nox1 and NoxA1 Supplementary Figure S4: Target of ubiquitination is not p47phox Supplementary Figure S5: PKC-dependent NoxO1 phosphorylation Supplementary Figure S6: Subcellular localization of NoxO1 and NoxA1 Supplementary Figure S7: Effect of NoxO1 on Erk activation
Supplementary References from Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies
Authors: Lee Hee-Sheung , Lee Nicholas C.O. , Kouprina Natalay , Kim Jung-Hyun , Kagansky Alex , Bates Susan , Trepel Jane B. , Pommier Yves , Sackett Dan , Larionov Vladimir
Published: March 2023

Supplementary References.
Supplementary Figures S1-S3 from Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies
Authors: Lee Hee-Sheung , Lee Nicholas C.O. , Kouprina Natalay , Kim Jung-Hyun , Kagansky Alex , Bates Susan , Trepel Jane B. , Pommier Yves , Sackett Dan , Larionov Vladimir
Published: March 2023

Depletion of several genes critical for proper chromosome segregation results in an increased rate of EGFP-HAC loss (S1); Effect of cells treatment by combinations of drugs targeting mitosis and necroptosis (S2); Rates of HAC loss in response cold- or heat-shock combined with the cells treatment by either taxol or LMP400 (S3).
Supplementary Figure S1 from RANK Signaling Blockade Reduces Breast Cancer Recurrence by Inducing Tumor Cell Differentiation
Authors: Yoldi Guillermo , Pellegrini Pasquale , Trinidad Eva M. , Cordero Alex , Gomez-Miragaya Jorge , Serra-Musach Jordi , Dougall William C. , Muñoz Purificación , Pujana Miguel-Angel , Planelles Lourdes , González-Suárez Eva
Published: March 2023

RANK and RANKL expression during MMTV-PyMT tumor progession
Supplementary Figures S1-S8 from Novel Morphologic and Genetic Analysis of Cancer Cells in a 3D Microenvironment Identifies STAT3 as a Regulator of Tumor Permeability Barrier Function
Authors: Park Min Chul , Jeong Hyobin , Son Sung Hwa , Kim YounHa , Han Daeyoung , Goughnour Peter C. , Kang Taehee , Kwon Nam Hoon , Moon Hyo Eun , Paek Sun Ha , Hwang Daehee , Seol Ho Jun , Nam Do-Hyun , Kim Sunghoon
Published: March 2023

Supplementary Figure S1. Characterization of cancer spheroids. Supplementary Figure S2. Characteristics of spheroids based on morphologic classification. Supplementary Figure S3. Validation of spheroid morphology-dependent characteristics. Supplementary Figure S4. Validation of PLS-DA model. Supplementary Figure S5. Network models describing cellular processes associated with spheroid subtypes. Supplementary Figure S6. Drug penetration test in spheroids using bimolecular fluorescence complementation (BiFC). Supplementary Figure S7. Molecular signature of GBM patient-derived round type spheroid. Supplementary Figure S8. Xenograft model to validate JAK-STAT pathway for drug sensitivity.
Supplemental Figure 1 from Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer
Authors: Cook Katherine L. , Soto-Pantoja David R. , Clarke Pamela A.G. , Cruz M. Idalia , Zwart Alan , Wärri Anni , Hilakivi-Clarke Leena , Roberts David D. , Clarke Robert
Published: March 2023

LCC9 (A) or ZR-75-1 (B) cells were transfected with control siRNA, GRP78 siRNA, or GRP78 cDNA for 24 hours and then plated in an ACEA E-plate in the presence of vehicle or 100 nM 4-OHT; cell index was measured by electrical impedance every 12 hours for 72 hours. n=3, *p<0.05 C. LCC9 tumor sections were stained using GRP78 antibodies or a no antibody control and visualized at 40x. D. PI3K p110 subunit, pAKT (Ser473 and Thr308), and AKT protein levels were measured in LCC9 control, TAM, human targeting GRP78M, and human targeting GRP78M+TAM treated xenograft tumor lysates by Western blot hybridization. Equivalence of protein loading was confirmed by measuring beta-actin.
Supplemental Materials and Methods from Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer
Authors: Merino Vanessa F. , Nguyen Nguyen , Jin Kideok , Sadik Helen , Cho Soonweng , Korangath Preethi , Han Liangfeng , Foster Yolanda M.N. , Zhou Xian C. , Zhang Zhe , Connolly Roisin M. , Stearns Vered , Ali Syed Z. , Adams Christina , Chen Qian , Pan Duojia , Huso David L. , Ordentlich Peter , Brodie Angela , Sukumar Saraswati
Published: March 2023

Supplemental Materials and Methods and Supplemental References
Supplementary Figure S6 from Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial
Authors: Erdem-Eraslan Lale , van den Bent Martin J. , Hoogstrate Youri , Naz-Khan Hina , Stubbs Andrew , van der Spek Peter , Böttcher René , Gao Ya , de Wit Maurice , Taal Walter , Oosterkamp Hendrika M. , Walenkamp Annemiek , Beerepoot Laurens V. , Hanse Monique C.J. , Buter Jan , Honkoop Aafke H. , van der Holt Bronno , Vernhout René M. , Smitt Peter A.E. Sillevis , Kros Johan M. , French Pim J.
Published: March 2023

Distinct molecular subtypes as defined by the TCGA of GBM show a trend towards benefit from Beva/CCNU treatment.
supplementary data figure legends from Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell–Mediated Antitumor Immunity
Authors: Brentville Victoria A. , Metheringham Rachael L. , Gunn Barbara , Symonds Peter , Daniels Ian , Gijon Mohamed , Cook Katherine , Xue Wei , Durrant Lindy G.
Published: March 2023

figure legends
Supplementary Figure S1 from Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin–GUCY2C Paracrine Signaling Axis
Authors: Lin Jieru E. , Colon-Gonzalez Francheska , Blomain Erik , Kim Gilbert W. , Aing Amanda , Stoecker Brian , Rock Justin , Snook Adam E. , Zhan Tingting , Hyslop Terry M. , Tomczak Michal , Blumberg Richard S. , Waldman Scott A.
Published: March 2023

Relative guanylin expression in proximal (PC) and distal (DC) colons of mice on lean or high fat (HF) diets.
Supplementary Table S1 from Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
Authors: Picon-Ruiz Manuel , Pan Chendong , Drews-Elger Katherine , Jang Kibeom , Besser Alexandra H. , Zhao Dekuang , Morata-Tarifa Cynthia , Kim Minsoon , Ince Tan A. , Azzam Diana J. , Wander Seth A. , Wang Bin , Ergonul Burcu , Datar Ram H. , Cote Richard J. , Howard Guy A. , El-Ashry Dorraya , Torné-Poyatos Pablo , Marchal Juan A. , Slingerland Joyce M.
Published: March 2023

Primer Sequences.
Supplementary Table S1 from Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo
Authors: Rao Shreyas S. , Bushnell Grace G. , Azarin Samira M. , Spicer Graham , Aguado Brian A. , Stoehr Jenna R. , Jiang Eric J. , Backman Vadim , Shea Lonnie D. , Jeruss Jacqueline S.
Published: March 2023

Characterization of micro-porous PLG and PCL scaffolds (N = 10).
Supplementary Figure S2 from ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis
Authors: Rodriguez Calleja Lidia , Jacques Camille , Lamoureux François , Baud'huin Marc , Tellez Gabriel Marta , Quillard Thibaut , Sahay Debashish , Perrot Pierre , Amiaud Jerome , Charrier Celine , Brion Regis , Lecanda Fernando , Verrecchia Franck , Heymann Dominique , Ellisen Leif W. , Ory Benjamin
Published: March 2023

miR-527 and miR-665 repress Smad4 and TÎ²RII, respectively.
Supplemental Figure S1 from MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell–Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages
Authors: Yamada Kazuya , Uchiyama Akihiko , Uehara Akihito , Perera Buddhini , Ogino Sachiko , Yokoyama Yoko , Takeuchi Yuko , Udey Mark C. , Ishikawa Osamu , Motegi Sei-ichiro
Published: March 2023

This file contains supplementary figure S1. Supplemental Figure S1: Proliferation and mRNA levels of MFG-E8 in MSC derived from BM in WT mice cultured under normoxia or hypoxia condition for 48 hours.
Supplemental Figure 5 from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: March 2023

DC-derived BAFF protects T-cells from activation-induced cell death.
Supplementary Figure Legends from Activation of Hematopoietic Stem/Progenitor Cells Promotes Immunosuppression Within the Pre–metastatic Niche
Authors: Giles Amber Jin , Reid Caitlin Marie , Evans Justin DeWayne , Murgai Meera , Vicioso Yorleny , Highfill Steven Lorenz , Kasai Miki , Vahdat Linda , Mackall Crystal Lee , Lyden David , Wexler Leonard , Kaplan Rosandra Natasha
Published: March 2023

Legends for Supplementary Figures 1-6.
Figure S6 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: March 2023

2D graph, showing normalized read count of the shared binding sites for ERalpha and FOXA1 (blue), ERalpha only (red) and FOXA1 only (green) in ChIP-seq datasets of all indicated transcriptional regulators in the endometrial cancer cell line Ishikawa (ENCODE, see Supplementary table S4).
Supplementary Table S6 from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: March 2023

Supplementary Table S6. TF and miRNA co-regulatory network for the Cell cycle and DNA repair pathways.
Supplementary Figures from Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma
Authors: Rao Shuyun , Cai Kathy Q. , Stadanlick Jason E. , Greenberg-Kushnir Noa , Solanki-Patel Nehal , Lee Sang-Yun , Fahl Shawn P. , Testa Joseph R. , Wiest David L.
Published: March 2023

This file contains supplementary figures 1-4. Supplementary Figure 1 provides supporting information for the effects of Rpl22 loss on thymic cellularity and supports Figure 1. Supplementary Figure 2 describes the phenotypes of periperhal T lineage cells, both normal and transformed, in Rpl22-sufficient and Rpl22-deficient mice. It supports the data in Figure 3. Supplementary Figure 3 depicts the maturation of single positive thymocytes in MyrAkt Tg Rpl22-deficient mice, revealing that maturation is not impaired. These data support Figure 5. Supplementary figure 4 depicts the effect of Rpl22 mutation on expression of KLF2 and S1PR1 in human T-ALL. It supports the data in Figure 6.
Supplementary Table S1,4 and Figures from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: March 2023

Supplementary Tables 1,4 and Figures.docx Supplementary Table S1: Summary of RNA-seq and smRNA-seq data Supplementary Table S4: The information of cancer related pathways Supplementary Figure S1: Project design and flowchart of the study Supplementary Figure S2: Cluster of differentially expressed genes Supplementary Figure S3: Heatmap of the expression of key TFs and miRNAs in the transformation Supplementary Figure S4: Regulatory network for K562-MVs highly expressed TFs and miRNAs Supplementary Figure S5: Expression of miR-146b-5p in K562-MVs after infection Supplementary Figure S6: Level of NUMB mRNA in the recipient cells when NUMB-lentivirus was transfected
Supplemental Information from Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function
Authors: Wang Weihuan , Zimmerman Grant , Huang Xiaoran , Yu Shuiliang , Myers Jay , Wang Yiwei , Moreton Stephen , Nthale Joseph , Awadallah Amad , Beck Rose , Xin Wei , Wald David , Huang Alex Y. , Zhou Lan
Published: March 2023

Supplemental Materials and Methods This file contains detailed methods of IHC, WB, CHIP assay, luciferase reporter assay, qRT-PCR and 2-photon imaging analysis and etc.
Supplementary Figure 4 from Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis
Authors: Nakajima Kosei , Kho Dhong Hyo , Yanagawa Takashi , Harazono Yosuke , Hogan Victor , Chen Wei , Ali-Fehmi Rouba , Mehra Rohit , Raz Avraham
Published: March 2023

Created customized anti-CRD antibody recognizes CRD of Gal-3.
Supplemental Figure 3 from STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis
Authors: Jones Laura M. , Broz Miranda L. , Ranger Jill J. , Ozcelik John , Ahn Ryuhjin , Zuo Dongmei , Ursini-Siegel Josie , Hallett Michael T. , Krummel Matthew , Muller William J.
Published: March 2023

Supplemental Figure 3:Stat3flx/flx/MTB/MIC tumors are unable to colonize the lungs in the presence or absence of an innate immune system
Supplementary Figure S4 from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: March 2023

Temporal profiles of 4 metabolic features identified by random forest analysis of control versus IR treated mice (taken from Table 1).
Supplementary Figure S3 from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: March 2023

Temporal profiles of a few selected metabolites.
Supplementary Materials and Methods from Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition
Authors: Herkert Barbara , Kauffmann Audrey , Mollé Sandra , Schnell Christian , Ferrat Thomas , Voshol Hans , Juengert Janina , Erasimus Hélène , Marszalek Grégory , Kazic-Legueux Malika , Billy Eric , Ruddy David , Stump Mark , Guthy Daniel , Ristov Mitko , Calkins Keith , Maira Sauveur-Michel , Sellers William R. , Hofmann Francesco , Hall Michael N. , Brachmann Saskia M.
Published: March 2023

Supplementary materials and methods.
Supplementary Figure 2 from Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival
Authors: den Hollander Petra , Rawls Kathryn , Tsimelzon Anna , Shepherd Jonathan , Mazumdar Abhijit , Hill Jamal , Fuqua Suzanne A.W. , Chang Jenny C. , Osborne C. Kent , Hilsenbeck Susan G. , Mills Gordon B. , Brown Powel H.
Published: March 2023

Supp Fig 2 - Cleaved caspase 7 is selective increased in basal-like breast cancers with low PTP4A3 expression.
Supplementary Figure Legends from PDLIM1 Stabilizes the E-Cadherin/β-Catenin Complex to Prevent Epithelial–Mesenchymal Transition and Metastatic Potential of Colorectal Cancer Cells
Authors: Chen Hai-Ning , Yuan Kefei , Xie Na , Wang Kui , Huang Zhao , Chen Yan , Dou Qianhui , Wu Min , Nice Edouard C. , Zhou Zong-Guang , Huang Canhua
Published: March 2023

Supplementary Figure Legends
Supplementary Table 2 from Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas
Authors: Tang Xiaohu , Wu Jianli , Ding Chien-Kuang , Lu Min , Keenan Melissa M. , Lin Chao-Chieh , Lin Chih-An , Wang Charles C. , George Daniel , Hsu David S. , Chi Jen-Tsan
Published: March 2023

Supplementary Table 2. Metabolomics of 786-O VHL-deficient and -restored cells upon cystine deprivation
Supplemental Table 1 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

List of potential ODC inhibitors generated by using computer screening.
Supplementary Figure Legends from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: March 2023

Supplemental figure legends
Supplementary Figure 6 from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: March 2023

Supplementary Figure 6. Downregulation of miR-892b is attributed to hypermethylation of its promoter.
Supplementary table 5 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: March 2023

Microarray and qPCR data showing no induction of PEMT mRNA levels by estrogen in MCF7 and T47D cells
Supplementary figure legends from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: March 2023

Legends of figures S1 to S9
Supporting data Fig 3A, 3B, 4D, S6 from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: March 2023

This file contains the following: source data for the graphs shown in Figure 3A (GI50, Z sub G1, and Z G1 increase); source data for the heatmap and graph shown in Figure 3B (expression fold change, log2 fold change, and gene score); qPCR source data for the heatmap and graph in Figure 4D; measurements of Western blotting band intensity from Figure S6.
Supplementary tables from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: March 2023

This file contains 4 supplementary tables: Table S1 provides the expression values of the indicated genes (RMA) in BETi sensitive and insensitive cell lines; Table S2 shows the enrichment of subtypes of cell lines following selection with the indicated criteria; Table S3 shows SNP analysis of parental and BETi tolerant A375 cells; Table S4 shows SNP analysis of parental and BETi tolerant NOMO-1 cells.
Figure S10 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: March 2023

Scheme showing the proposed relation between Pax3-FoxO1 induced expression of HO-1 and miR-206 dependent pathway.
Figure S1 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: March 2023

Comparison of SMS-CTR eRMS (SMS) and CW9019 aRMS (CW) cell lines cultured under standard conditions. Expression of VEGF, VEGFR-1, VEGFR-2, HIF-1, HIF-2 and miR-146a genes.
Supplemental Tables S1-S2 from Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages
Authors: Zhao Jun-Long , Huang Fei , He Fei , Gao Chun-Chen , Liang Shi-Qian , Ma Peng-Fei , Dong Guang-Ying , Han Hua , Qin Hong-Yan
Published: March 2023

Table S1: Primers and oligonucleotides used for PCR. Table S2: Antibodies and related reagents used in this study.
Supplementary Materials and Methods, Supplementary Tables 1 and 2 and Supplementary Figures 1 through 5 from PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers
Authors: Labbé David P. , Uetani Noriko , Vinette Valérie , Lessard Laurent , Aubry Isabelle , Migon Eva , Sirois Jacinthe , Haigh Jody J. , Bégin Louis R. , Trotman Lloyd C. , Paquet Marilène , Tremblay Michel L.
Published: March 2023

Supplementary Materials and Methods. Table S1: List of the different oligonucleotides used for mouse genotyping. Table S2: Phenotypic evaluation of prostate-specific PTP1B-overexpressing mice. Figure S1: Ptpn1 status does not alter the transition to mPIN in PtenPE-/- mice. Figure S2: Examples of mild and moderate desmoplasia. Figure S3: HFD drives invasive prostate cancer in the AP only in absence of Ptpn1. Figure S4: Ptpn1 status does not modulate mPIN formation in PtenPE+/- mice. Figure S5: Ptpn1 status influences PtenPE-/- phenotype in a dose-dependent manner.
Figure S9 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: March 2023

miR-214 and miR-148b affect migration and invasion ability
Figure S3 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: March 2023

miR-214 expression modulations in normal or tumor breast cells
Supplementary Table 6 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: March 2023

List of the Tumor types having mutations in both MYH9 and RHOA genes in the cBioPortal for Cancer Genomics database
Supplementary Table 5 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: March 2023

List of SNVs identified in the analyzed genes
Figure S10 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: March 2023

miR-214 inhibition and miR-148b overexpression impair melanoma cell extravasation
Supplementary Table 1 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: March 2023

Whole genome sequencing data analysis of 10 MPM tumor and matched DNA generated by Complete Genomics platform
Supplementary Figure 2 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: March 2023

Schematic representation of the SNVs and/or chromosomal aberrations identified in BAP1, NF2, TP53, MYH9, RHOA, MYH6, MYH10, PIK3C2A, TNFRSF1A, and 22q and 9p in a panel of 147 MPM tumors.
Supplementary Figure 1 and 2 from Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations
Authors: Riquelme Erick , Behrens Carmen , Lin Heather Y. , Simon George , Papadimitrakopoulou Vassiliki , Izzo Julie , Moran Cesar , Kalhor Neda , Lee J. Jack , Minna John D. , Wistuba Ignacio I.
Published: March 2023

EZH2 and MEK-ERK and PI3K/AKT signaling pathway expression in lung adenocarcinoma and HBEC cell lines KRAS wild-type and with different amino acid substitutions in codon 12 KRAS mutants and Sensitivity in vitro to AZD6244 and MK2206 was significantly increased in the presence of highly selective EZH2 inhibitor GSK343, EPZ6438 and GSK126 in NSCLC cells expressing mutant KRASG12C and KRASG12D, respectively
Supplementary Figure S4 from Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models
Authors: O'Connor James P.B. , Boult Jessica K.R. , Jamin Yann , Babur Muhammad , Finegan Katherine G. , Williams Kaye J. , Little Ross A. , Jackson Alan , Parker Geoff J.M. , Reynolds Andrew R. , Waterton John C. , Robinson Simon P.
Published: March 2023

MRI relationship to Hoechst 33342 and H&E
Supplemental Table 2 from Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease
Authors: Murphy Stephen J. , Hart Steven N. , Halling Geoffrey C. , Johnson Sarah H. , Smadbeck James B. , Drucker Travis , Lima Joema Felipe , Rohakhtar Fariborz Rakhshan , Harris Faye R. , Kosari Farhad , Subramanian Subbaya , Petersen Gloria M. , Wiltshire Timothy D. , Kipp Benjamin R. , Truty Mark J. , McWilliams Robert R. , Couch Fergus J. , Vasmatzis George
Published: March 2023

Combined Mate Pair and Whole Exome Sequencing data for all 24 tumors described in this study.
Supplementary Table S3 from Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
Authors: Popova Tatiana , Manié Elodie , Boeva Valentina , Battistella Aude , Goundiam Oumou , Smith Nicholas K. , Mueller Christopher R. , Raynal Virginie , Mariani Odette , Sastre-Garau Xavier , Stern Marc-Henri
Published: March 2023

Summary for structural alterations detected by paired-end WGS for 25 TCGA ovarian tumors
Supplementary Methods from Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
Authors: Popova Tatiana , Manié Elodie , Boeva Valentina , Battistella Aude , Goundiam Oumou , Smith Nicholas K. , Mueller Christopher R. , Raynal Virginie , Mariani Odette , Sastre-Garau Xavier , Stern Marc-Henri
Published: March 2023

Supplementary Materials and Methods and References
Supplementary Table S1 from PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling
Authors: Hein Ashley L. , Seshacharyulu Parthasarathy , Rachagani Satyanarayana , Sheinin Yuri M. , Ouellette Michel M. , Ponnusamy Moorthy P. , Mumby Marc C. , Batra Surinder K. , Yan Ying
Published: March 2023

Clinical characteristics of the PDAC specimens used for the study of PR55Î± expression by IHC
Supplementary Figure S3 from PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling
Authors: Hein Ashley L. , Seshacharyulu Parthasarathy , Rachagani Satyanarayana , Sheinin Yuri M. , Ouellette Michel M. , Ponnusamy Moorthy P. , Mumby Marc C. , Batra Surinder K. , Yan Ying
Published: March 2023

Effect of PR55Î± expression on mobility of pancreatic cancer cells.
Supplementary Figure S1 from PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling
Authors: Hein Ashley L. , Seshacharyulu Parthasarathy , Rachagani Satyanarayana , Sheinin Yuri M. , Ouellette Michel M. , Ponnusamy Moorthy P. , Mumby Marc C. , Batra Surinder K. , Yan Ying
Published: March 2023

Effect of PR55Î± expression on BAD and Î²-catenin
Supplementary Figures S1-S11 from Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma
Authors: Perumal Deepak , Kuo Pei-Yu , Leshchenko Violetta V. , Jiang Zewei , Divakar Sai Krishna Athaluri , Cho Hearn Jay , Chari Ajai , Brody Joshua , Reddy M.V. Ramana , Zhang Weijia , Reddy E. Premkumar , Jagannath Sundar , Parekh Samir
Published: March 2023

Mechanism of ON123300 induced MM cell death (S1); PD0332991 less significantly induces apoptosis in MM1.S cell and does not induce apotosis in NCI-H929 cells (S2); PD0332991 induces cell cycle arrest in MM1.S cells and not in NCI-H929 cells (S3); ON123300 induces cell cycle arrest in MM cells (S4); Molecular effects of treatment with PD0222991 in MM cell lines (S5); Effects of ARK5 depletion on MM cell viability by siRNA transfected MM1.S and NCI-H929 cells (S6); Anti-MM activity of SRT1720 (S7); Effect of ARK5 silencing by siRNA induces apoptosis in MM (S8); Effect of ARK5 silencing by siRNA enhances G1/S cell cycle arrest in MM (S9); ON123300 overcomes bone marrow stromal cell (BMSC) induced growth of MM Cells (S10); In vivo MM xenograft ON123300 inhibition (S11).
Supplementary Figure legends from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: March 2023

Supplementary Figure legends
Supplementary Figure S6 from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: March 2023

Prodigiosin-mediated p53 pathway restoration and cell death involves c-Jun activation.
Supplementary Figure S5 from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: March 2023

Prodigiosin-mediated p53 pathway restoration, cell death and anti-CRCSC effect involves inhibition of Î”Np73.
Supplementary Figure Legends from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: March 2023

Supplementary figure legends
Supplementary Figure 7 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: March 2023

Fig. S7 LF3 reduces tumor growth without showing toxicity in vivo.
Supplementary Figure 3 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Authors: Crottès David , Rapetti-Mauss Raphael , Alcaraz-Perez Francisca , Tichet Mélanie , Gariano Giuseppina , Martial Sonia , Guizouarn Hélène , Pellissier Bernard , Loubat Agnès , Popa Alexandra , Paquet Agnès , Presta Marco , Tartare-Deckert Sophie , Cayuela Maria Luisa , Martin Patrick , Borgese Franck , Soriani Olivier
Published: March 2023

Control experiments showing specificity of PLA assay between hERG and β1 integrin
Supplementary Figure 4 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: March 2023

Fig. S4 LF3 doesn't cause apoptosis or cell death.
Supplementary Figure 1 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: March 2023

Fig. S1 Technology and protein production for the primary High Throughput Screen (HTS).
Supplementary Table S3 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: March 2023

Multivariate analysis of recurrence-free survival regarding prognostic information of SMAD2 phosphorylation.
Supplementary Figures 1 through 5 from Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer
Authors: Concha-Benavente Fernando , Srivastava Raghvendra M. , Trivedi Sumita , Lei Yu , Chandran Uma , Seethala Raja R. , Freeman Gordon J. , Ferris Robert L.
Published: March 2023

Supplementary Figure 1. IFNγ-induced PD-L1 upregulation is not PI3K dependent. Supplementary Figure 2. IFNα induces pSTAT1 and HLA class I upregulation. Supplementary figure 3. A. STAT1 and STAT3 siRNA knockdown efficiency. Supplementary figure 4. EGF induces JAK2 phosphorylation. Supplementary figure 5. Knockdown efficiency of STAT1 siRNA in HNC cell lines.
Supplementary Materials and Methods, Supplementary Figure Legends, and Supplementary Tables 1 through 5 from SSBP1 Suppresses TGFβ-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling
Authors: Jiang Hong-Lin , Sun He-Fen , Gao Shui-Ping , Li Liang-Dong , Huang Sheng , Hu Xin , Liu Sheng , Wu Jiong , Shao Zhi-Ming , Jin Wei
Published: March 2023

Supplementary Materials and Methods, Supplementary Figure Legends, Supplementary Table S1 Alteration of SSBP1 protein expression levels in relation to clinicopathological characteristics in breast cancer patients. Supplementary Table S2 Antibodies used in this study. Supplementary Table S3 Primers for plasmid construction. Supplementary Table S4 Primers for ChIP. Supplementary Table S5 iTRAQ: Dysregulated proteins with gene symbol.
Supplementary Figure S1 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: March 2023

Flow chart of SBII2 cohort study design regarding analysis of TGFBR2 and pSMAD2 biomarker.
Supplementary Table 1 from NFAT1 Directly Regulates IL8 and MMP3 to Promote Melanoma Tumor Growth and Metastasis
Authors: Shoshan Einav , Braeuer Russell R. , Kamiya Takafumi , Mobley Aaron K. , Huang Li , Vasquez Mayra E. , Velazquez-Torres Guermarie , Chakravarti Nitin , Ivan Cristina , Prieto Victor , Villares Gabriel J. , Bar-Eli Menashe
Published: March 2023

Top potential genes downregulated after silencing NFAT1
supplemental figure legends from Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone–Related Protein
Authors: Kim Wonnam , Takyar Farzin M. , Swan Karena , Jeong Jaekwang , VanHouten Joshua , Sullivan Catherine , Dann Pamela , Yu Herbert , Fiaschi-Taesch Nathalie , Chang Wenhan , Wysolmerski John
Published: March 2023

supplemental figure legends
Supplementary Figure 2 from NFAT1 Directly Regulates IL8 and MMP3 to Promote Melanoma Tumor Growth and Metastasis
Authors: Shoshan Einav , Braeuer Russell R. , Kamiya Takafumi , Mobley Aaron K. , Huang Li , Vasquez Mayra E. , Velazquez-Torres Guermarie , Chakravarti Nitin , Ivan Cristina , Prieto Victor , Villares Gabriel J. , Bar-Eli Menashe
Published: March 2023

Relative mRNA expression of NFAT1, IL-8, and MMP-3
Supplemental Figure Legends from Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy
Authors: Pilon-Thomas Shari , Kodumudi Krithika N. , El-Kenawi Asmaa E. , Russell Shonagh , Weber Amy M. , Luddy Kimberly , Damaghi Mehdi , Wojtkowiak Jonathan W. , Mulé James J. , Ibrahim-Hashim Arig , Gillies Robert J.
Published: March 2023

Supplemental Figure Legends
Supplementary Figure 1 from Alox5 Blockade Eradicates JAK2V617F-Induced Polycythemia Vera in Mice
Authors: Chen Yaoyu , Shan Yi , Lu Min , DeSouza Ngoc , Guo Zhiru , Hoffman Ronald , Liang Aibin , Li Shaoguang
Published: March 2023

Supplemental Figure 1. Comparison of transduction efficiency of JAK2V617F retrovirus between WT and Alox5-/- donor bone marrow cells. Bone marrow cells from WT or Alox5-/- donor mice were transduced with JAK2V617F retrovirus, and transduced with the same virus again 24 hours later. Prior to injection into recipient mice, the percentages of GFP+ cells were analyzed by FACS. Some cells were cultured for two more days (72 hours after initial viral transduction), and then the percentages of GFP+ cells were analyzed.
Supplementary Tables 1 though 7 from Balancing Protein Stability and Activity in Cancer: A New Approach for Identifying Driver Mutations Affecting CBL Ubiquitin Ligase Activation
Authors: Li Minghui , Kales Stephen C. , Ma Ke , Shoemaker Benjamin A. , Crespo-Barreto Juan , Cangelosi Andrew L. , Lipkowitz Stanley , Panchenko Anna R.
Published: March 2023

Table S1. Classification of mutations and definition of different classes. Table S2. P-values for different null hypotheses calculated by two-sample t-test. Table S3. Top 25% cancer mutations with the largest energy changes for each state in CBL activation cycle. Table S4. Binding free energy for wild-type CBL-E2-S and pCBL-E2-S states. Table S5. Pearson correlation coefficients (R) between experimental densitometry values and predicted changes in stability and binding affinity. Table S6. True positive rates are listed corresponding to different false positive rates. Table S7. Experimental relative densitometry values for HEK293T cell line, predicted changes in stability, binding affinity and comparison with other methods for 15 experimentally tested mutations.
Supplementary Figure S2 from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: March 2023

Verification of computational E. coli typing based on fimH mutation patterns. (A) Estimation of the factorization rank r in nonnegative matrix factorization (NMF). NMF analysis using 4 as the factorization rank r revealed that fimH could be classified into four types. (B) Consensus sequence of each type of fimH. Consensus sequences were illustrated by WebLogo using stacks of symbols. The size of symbols indicates the relative frequency of each base at that position.
Supplementary Figure Legends from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: March 2023

Legends of Supplementary Figure S1-S4
Supplementary Table S3 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Summary of Validation Studies.
Supplementary Figure S5 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: March 2023

Arginase expression analysis