bluuebunny/crossref_metadata_2025 huggingface dataset:
Devonian succession in the East-Zilair zone: conodont-based subdivision and paleontological verification
Authors: Artushkova O. V. , Maslov V. A.
Published: March 2022

Research subject. Conodont-based biostratigraphic subdivision of the monotonous siliceous-terrigenous sequence stratigraphically underlying the Famennian Zilair Formation.Materials and methods. Conodont imprints on the bedding planes from our own collections along with the data from other researchers were used for dating and subdivision of siliceous formations.Results. Our study of conodonts from the deposits underlying the Zilair Formation at a number of intersections on the eastern side of the Zilair synclinorium showed that the stratigraphic scale of the straton, previously recognised as the “Betrinskaya Formation”, should be revised. Numerous collections from well-known and many new localities have proved that the terrigenous-siliceous deposits occurring stratigraphically below the graywackes of the Zilair Formation, in fact constitute the sequence of the entire Devonian section and include characterised by conodonts intervals of the upper Pragian and Emsian stages of the Lower Devonian, the Eifelian and Givetian stages of the Middle Devonian, and the Frasnian stage of the Upper Devonian. These deposits compose a lithologically homogeneous straton – the Novousmanovo succession with siliceous rocks prevailing in its section. The isolation of indicative siliceous members, in particular the Ibragimov horizon, is inexpedient due to the lithological uniformity of the succession as a whole, and its facies variability along the lateral. The limestone members included in it are dated by conodonts. They belong to different stratigraphic intervals and occur in situ in the section.Conclusions. The sediments stratigraphically underlying the Zilair Formation and fully comparable with the identified Novousmanovo succession are developed in the Kuragan-Sakmara zone (Akchura (D1), the remote facies of the Utyagulovo (D2 ef) and Sarbai (D2-D3f) Formations). In the West Magnitogorsk zone in the Voznesenka-Sakmara subzone below the Zilair Formation in a similar siliceous succession, a sequence in conodont zones of stratigraphic intervals of the Eifelian and Givetian stages (D2) and Frasnian stage (D3) united into the Aktau Formation are revealed.
Acute demyelinating encephalomyelitis and transverse myelitis in a child with COVID-19
Authors: Poyrazoğlu Hatice Gamze , Kırık Serkan , Sarı Mehmet Yusuf , Esen İhsan , Toraman Zülal Aşçı , Eroğlu Yeşim
Published: March 2022

Background. Corona virus disease 2019 (COVID-19) includes a wide range of diseases with varying pathophysiology in children and adults. Although the disease mainly affects the respiratory tract, neurological involvement is also reported in the literature. The most common neurological complaints due to COVID-19 are headache, dizziness and anosmia. Acute necrotizing myelitis, acute demyelinating encephalomyelitis (ADEM), acute axonal neuropathy, acute transverse myelitis, and Guillian-Barre syndrome have been reported as neurological dysfunctions associated with COVID-19.
Case. A ten-year-old male patient presented with complaints of fever, headache and generalized muscle pain. The patient developed inability to walk and significant muscle weakness during the disease course, and he was diagnosed with ADEM and transverse myelitis on magnetic resonance imaging (MRI). As the etiological agent, COVID-19 was detected in both the respiratory panel sample and the cerebrospinal fluid (CSF) sample by the polymerase chain reaction (PCR) technique. Pulse steroid, IVIG, and plasmapheresis treatment were administered. He started to stand with support during follow-up.
Conclusion. We presented a case of COVID-19 related ADEM and transverse myelitis who responded to pulse steroid, IVIG, and plasmapheresis.
Chest imaging for COVID-19: a single-center comparative results in pediatric patients
Authors: Özcan H Nursun , Özsürekci Yasemin , Oğuz Berna , Oygar Pembe Derin , Gürlevik Sibel Laçinel , Karakaya Jale , Tekşam Özlem , Ceyhan Mehmet , Haliloğlu Mithat
Published: March 2022

Background. Chest computed tomography (CT) appears to be an important radiological modality for the diagnosis of COVID-19 in adults. Studies comparing the findings of such children with those of other viral infections have not been reported either. The aim of this study was to present comparative imaging findings of 75 pediatric COVID-19 patients and four patients with other viral upper respiratory tract infections. We also aimed to demonstrate the possible association between the radiological and laboratory findings in the COVID group.
Methods. From 11 March 2020 to 20 June 2020, 79 children (aged < 18 years) were enrolled. COVID-19 was detected by RT-PCR or antibody testing. A plain chest X-ray was obtained from all subjects. Non-contrast chest CT was performed for symptomatic patients.
Results. Seventy-five patients had COVID-19 and 4 were infected with other pathogens i.e. adenovirus, rhinovirus, parainfluenza virus B, respiratory syncytial virus. The ages of the patients (36 M, 43 F) ranged from 7 months to 17 years old. The sensitivity of chest X-ray (as compared to RT-PCR) was 10.67% (95 CI%: 4.72 - 19.94%). From 23 chest CT`s five of them were normal and nine of them had only nodules ( < 5mm). The sensitivity of CT was 78.26% (95CI%: 54.30 - 92.54%), false-negative rate was 21.7%.
Conclusions. The sensitivity of chest CT was found to be low and any significant correlations could have not been depicted, between the radiological parameters and the presence of lymphopenia. Clinical follow-up combined with corresponding pathogen detection, and chest CT of the symptomatic COVID-19 patients might be a feasible/prompt protocol in children.
The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
Authors: Gazi Umut , Sayan Murat , Çakır Nedim , Süer Kaya , Beyitler İlke , Dalkan Ceyhun , Şanlıdağ Burçin , Ruh Emrah , Sarıoğlu Ayşe Arıkan , Şanlıdağ Tamer
Published: March 2022

Background. While children were initially thought to have serious contributions to the coronavirus disease 2019 (COVID-19) transmission, recent studies suggest otherwise. However, the possible effect of asymptomatic pediatric spread still has not yet received enough attention. The aim of our study was to estimate asymptomatic infection rates among children in the Turkish Republic of Northern Cyprus, by using pediatric patients admitted to a university hospital without any COVID-19-associated symptoms.
Methods. Blood samples collected from 80 pediatric patients with no symptoms and history of COVID-19 infection, who were admitted to a university hospital between September 2020 and January 2021, were included in the retrospective study. Isolated serum samples were tested by Dia.Pro SARS-CoV-2 IgG ELISA assays.
Results. The patient group included 40 (50%) male and 40 (50%) female patients. The average age of children was 7.6 ± 4.0 years, with min-max ages ranging from 2 to 15 years. Among the 80 patients tested, only one (1.3%) was detected positive by the Dia.Pro IgG ELISA kit.
Conclusions. The asymptomatic seropositivity reported in our study suggests the use of randomly performed serologic tests to monitor SARS-CoV-2 infection among the pediatric population in schools that would contribute to the public health fight against COVID-19.
The role of immature granulocyte percentage in predicting acute chest syndrome and the severity of the vaso-occlusive crisis in sickle cell disease
Authors: Karahan Feryal , Ünal Selma , Topçu Dilara Bal , Öztaş Yeşim , Bozlu Gülçin
Published: March 2022

Background. Sickle cell disease (SCD) is an inflammatory disease that can result in both chronic and acute inflammation. Immature granulocytes (IG) are not-yet-mature white blood cells that can be easily detected in complete blood count (CBC) tests. In recent studies it has been suggested that IG may play a role in determining the prognosis of inflammatory diseases. The aim of our study was to investigate the role of IG percentage on predicting acute chest syndrome (ACS) and the severity of vaso-occlusive crisis (VOC) in patients with SCD.
Methods. The study cohort consisted of 49 SCD patients admitted to the emergency department for VOC. If symptoms did not regress despite appropriate treatment including hydration and analgesia, they were hospitalized. Patients whose symptoms regressed were discharged from the emergency department within 24 hours. Blood samples, including CBC and C-reactive protein (CRP), a marker of inflammation, were taken within the first hour of admission. Steady state laboratory parameters from the previous visit in the last three months were collected from patient files.
Results. The mean age was 18±4 (range 8-25) years. Most were hospitalized (41/49; 83.7%) and 8 of 49 were discharged from the emergency department after their treatment for VOC. ACS developed in 13 of 49 (26.5%). White blood cell, neutrophil and nucleated red blood cell counts, percentage of IG (IG%) and CRP levels were significantly increased in patients with VOC. IG% of patients with ACS was significantly higher than patients without ACS. However, ROC analysis showed that IG% was not associated with the development of ACS or hospitalization for VOC.
Conclusions. Despite a small SCD cohort, the significant increase in the IG% in patients with VOC compared to their baseline values has suggested a role for IG% in predicting VOC. Although IG% was higher in ACS, its utility in predicting ACS was poor.
INVESTIGATION OF THE PROCESS AND PRODUCTS OF CALCINATION OF COMPOSITE GRANULES BASED ON HYDROXYAPATITE, WOLLASTONITE AND GELATINE
Authors:   Omsk State Medical University, Omsk, Russia, Solonenko A. P. , Shevchenko A. E. ,   Omsk State Medical University, Omsk, Russia, Rozdestvensky A. A. ,   Omsk State Medical University, Omsk, Russia, Dzyuba G. G. ,   Omsk State Medical University, Omsk, Russia
Published: March 2022

Контроль состава биоматериалов после проведения термической обработки имеет важное значение при создании новых их вариантов, поскольку многие биосовместимые синтетические вещества неустойчивы при высоких температурах, а в многокомпонентных системах возможно взаимодействие между составляющими с образованием новых продуктов. В данной работе выполнено исследование процесса прокаливания композитных гранул с варьируемым содержанием гидроксиапатита и волластонита и желатина, выполняющего роль связующего полимера. Установлено, что термическая обработка материалов сопровождается изменением их фазового состава, вызванного разложением апатита, фазовым переходом β-CaSiO3 в α-форму и образованием силикофосфата кальция (в образцах, где апатит - основной компонент). При этом состав продуктов прокаливания зависит от пропорции апатит/волластонит в материале.
New Fluorescent Powders for the Development of Latent Fingermarks
Authors:   Punjab Forensic Science Agency, Home Department, Government of the Punjab, Lahore, Pakistan, MI Ashiq , M Ur Rehman ,   Punjab Forensic Science Agency, Home Department, Government of the Punjab, Lahore, Pakistan, A Ali ,   Punjab Forensic Science Agency, Home Department, Government of the Punjab, Lahore, Pakistan, SA Wattoo ,   Punjab Forensic Science Agency, Home Department, Government of the Punjab, Lahore, Pakistan, M Amjad ,   Punjab Forensic Science Agency, Home Department, Government of the Punjab, Lahore, Pakistan, MA Tahir ,   Punjab Forensic Science Agency, Home Department, Government of the Punjab, Lahore, Pakistan
Published: March 2022

New and inexpensive fluorescent powders have been prepared and used for the development of latent fingermarks on non-porous and semi porous surfaces. 10mM solutions of rhodamine 6G and basic yellow 40 dyes were used to prepare dye coated fluorescent silica gel powders. Results of these new fluorescent powders were compared with results of commercially available fluorescent powders. The new powders have shown results comparable with those of commercially available powders so can be easily prepared and used as an alternate, if commercial fluorescent powders are not available.
One Hundred Years Ago New and Original Way for Teaching, Learning, Going Under the Surface
Authors:   Department of Clinical Medicine, University of Milan, Italy, F Carelli
Published: March 2022

It is the explanation and the unusual and special way through new and original ways for teaching and learning, also in very young ages, going under the surface, involving and how to create the interest and how to maintain it through the time. It involve active participation, creativity, imagination, looking from different points of view so to maintain this attitude lifelong and to maintain interest as well, sustaining interest for further discoveries. In teaching our medical students, we push and encourage and motivate them, for instance, asking how they feel about themselves in situations they have to face going under the appearances.
Russian Spatial Development Strategy: blind spots in regional specialisations
Authors: Kozyr N. S.
Published: March 2022

The state “Russian Spatial Development Strategy for the period up to 2025” has not only aroused interest in the scientific community, but has also been the object of criticism on the issues of  consistency of the prospective economic specialisations of the constituent entities of the Russian Federation to spatial development objectives. To identify gaps in the content of this strategy, the article compares the economic specialisations of the constituent entities of the Russian Federation with the types of activities described in the “Russian Classification of Economic Activities (OKVED-2) 2021”. The data obtained were compared with the gross value added statistics of the Russian industry structure. The representation of high-tech and knowledge-intensive industries in promising regional economic specialisations was analysed. The results of the study extend the list of criticisms from the Russian scientific community regarding the indicated document. However, a review of foreign studies has shown that the difficulties of strategy development are also inherent in countries with strong planning traditions. An unambiguous conclusion is the need to create a new structure and content document, taking into account the trends in the world and society technological development.
Monitoring the efficiency of organisation’s internal control and economic security system
Authors: Ageeva O. A. , Matytsyna Yu. D.
Published: March 2022

The article reviews the content and economic role of monitoring financial and economic activities. The aim of the study is to determine the essence of one of the main elements that make up the internal control system, namely: monitoring, which ensures the economic entity economic security. The subject is an indicative monitoring system, with the help of which risks are identified in a certain segment of the enterprise activity, that is, at the micro level. The research methodology consisted in the information collection and generalisation in order to build a scientific hypothesis about the subject under study, as well as in the recommendations development to improve the internal control system efficiency in the direction of ensuring the economic entity economic security. As a result, the authors proposed a monitoring algorithm that ensures the internal control system and economic security effectiveness.
Economy regional features and specialist training structure
Authors: Lebedev K. V. , Vasilyeva L. V. , Sumenova E. S.
Published: March 2022

In recent years, special attention is paid to increasing the regional role in training personnel for the economy and social sphere, to implementing the “Strategy for Scientific and Technological Development of the Russian Federation”, and to balanced development of the entire territory of Russia. The purpose of the article is to study the regional economic features of the Russian Federation members in relation with a personnel training structure with higher education. The sectoral specialisation of the Russian Federation members is assessed in the article on the example of the Siberian Federal District. The assessment is based on a comprehensive analysis of the sectoral structures of the Russian Federation members, economic activities localisation, population employment. It is emphasised that a degree of sector production concentration, which characterise the sectors importance in a national scale, must be taken into account. This will make it possible to optimise the personnel training structure with higher education. A comparison of specialists graduation in terms of specialties and areas enlarged groups with the population employment structure has shown that the regions specifics are not sufficiently taken into account by the training areas of higher education institutions. The results of the study can be useful to the top management of higher education institutions in the Russian regions.
Automated Bioanalytical Workflow for Ligand Binding Based Pharmacokinetic Assay Development
Authors: Evans Brad , Yeung Lai , Beck Armen , Li Annie , Lee Dong Hun , Chopra Gaurav , Bateman Kevin
Published: March 2022

The growth of therapeutic monoclonal antibodies continues to accelerate due to their success as treatments for many diseases. As new therapeutics are developed, it is increasingly important to have robust bioanalytical methods to measure the pharmacokinetics of the circulating therapeutic monoclonal antibodies (mAbs) in serum. Ligand-binding assays such as enzyme-linked immunosorbent assays (ELISA) utilizing anti-idiotypic (anti-ID) antibodies against the variable regions of the antibody, are a sensitive and specific bioanalytical method routinely used to measure levels of therapeutic antibodies in a biological matrix. Screening and selecting optimal reagents and assay format are critical steps in the development of robust assays. An additional complication exists for soluble circulating drug, mAb targets that could interfere with the anti-IDs binding to the therapeutic mAb resulting in underestimation of total drug concentrations. Therefore, the selection of anti-IDs and the assay format that are not impacted by soluble antigen is paramount to development of a successful pharmacokinetic (PK) assay. We have developed an automated workflow and scoring system that allows for ranking of candidate anti-IDs on a variety of criteria. A primary generic automated indirect ELISA was utilized to shortlist the anti-IDs that need to be labeled and screened in pairs. A secondary screen using a sandwich ELISA with labeled-anti-ID pairings tested multiple PK assay formats to identify the best anti-ID pairing/PK assay format. We demonstrate the use of automation and a scoring system that allows for screening of anti-IDs and identification of the most robust PK assay format in a significantly reduced timeframe compared to standard approaches.
Umpolung of Indoles: Triflic Acid-Mediated C3-Regioselective Hydroarylation of N-H Indoles
Authors: Sabat Nazarii , Zhou Weiping , Gandon Vincent , Guinchard Xavier , VINCENT Guillaume
Published: March 2022

The direct dearomative addition of arenes to the C3-position of unprotected indoles is reported under operationally simple condi-tions, using triflic acid at room temperature. The present regioselective hydroarylation is a straightforward manner to generate an electrophilic indole at the C3-position without the need of a deactivating acetyl group at the indolic nitrogen as in previously reported strategies. This atom economical method delivers biologically relevant 3-arylindolines and 3,3-spiroindolines in high yields and regioselectivities from both intra- and intermolecular processes. DFT computations suggest the stabilization of cationic or dicationic intermediates with H-bonded (TfOH)n clusters.
CoPriNet: Deep learning compound price prediction for use in de novo molecule generation and prioritization.
Authors: Sanchez-Garcia Ruben , Havasi Dávid , Takács Gergely , Robinson Matthew C. , Lee Alpha , von Delft Frank , Deane Charlotte M.
Published: March 2022

Compound availability is a critical property for design prioritization across the drug discovery pipeline. Historically, and despite its multiple limitations, compound-oriented synthetic accessibility scores have been used as proxies for this problem. However, the size of the catalogues of commercially available molecules has dramatically increased over the last decade, redefining the problem of compound accessibility as a matter of budget. In this paper we show that if compound prices are an alternative proxy for compound availability, then synthetic accessibility scores are not effective strategies for assessing availability. Instead, we learn how to predict prices directly from the catalogues. Our approached, CopriNet, is a retrosynthesis-free deep learning model trained on pairs of compound/prices extracted from the Mcule catalogue. CoPriNet is able to provide price predictions that exhibit far better correlation with actual compound prices than any synthetic accessibility measurement. Moreover, unlike standard retrosynthesis methods, CoPriNet is rapid, comparable in execution time to popular synthetic accessibility metrics and thus is suitable for high-throughput experiments including virtual screening and de novo compound generation.
Enhanced methanol production over non-promoted Cu-MgO-Al2O3 materials with ex-solved 2 nm Cu particles: Insights from an Operando spectroscopic study
Authors: Cored Jorge , Mazarío Jaime , Cerdá-Moreno Cristina , Lustemberg Pablo G. , Ganduglia-Pirovano M. Verónica , Domine Marcelo , Concepción Patricia
Published: March 2022

Enhanced methanol production is obtained over a non-promoted Cu-MgO-Al2O3 mixed oxide catalyst derived from a Cu-Mg-Al hydrotalcite precursor (HT) containing narrowly distributed small Cu NPs (2 nm). Conversions close to the equilibrium (20%) with a methanol selectivity of 67% are achieved at 230 °C, 20 bar and space velocity of 571 mL.gcat-1.h-1. Based on operando spectroscopic studies, the striking activity of this Cu based catalyst is ascribed to the stabilization of Cu+ ions favored under reaction conditions due to lattice reorganization associated with the “HT-memory effect”, promoted by water. Temperature resolved IR-MS experiments have enabled the discernment of monodentate formate species, stabilized on Cu+ as the intermediate in methanol synthesis, in line with the results of DFT calculations. These monodentate formate species are much more reactive than bridge formate species, behaving the last ones as intermediates in methane and CO formation. Moreover, poisoning of the Cu0 surface by strongly adsorbed species behaving as spectators is observed under reaction conditions. This work represents a detailed spectroscopic study highlighting the influence of the reaction pressure on the stabilization of active surface sites, and the possibility of enhancing methanol production on usually less active non-promoted nano-sized copper catalysts, providing that the proper support is selected, allowing the stabilization of doped Cu+. Thus, methanol formation rate of 2.6·10-3molMeOH·gcat-1·h-1 at 230 °C, 20 bar and WHSV = 28500 mL·gcat-1·h-1, is obtained on the Cu-MgO-Al2O3 HT-derived catalyst with 71% methanol selectivity, compared to 2.2·10-4 molMeOH·gcat-1·h-1 with 54% methanol selectivity obtained on a reference Cu/(Al2O3-MgO) catalyst not derived from a HT structure.
Transformer Oil Nanofluids by Two Dimensional hexagonal Boron Nitride Nanofillers
Authors: Bhunia Mississippi Missouri , Chattopadhyay Paramita , Chattopadhyay Kalyan Kumar
Published: March 2022

This paper explores the fascinating properties of two-dimensional (2D) nanofillers based transformer oil (TO) nanofluids. Nanofluids of 2D hexagonal boron nitride (h-BN) nanosheets in TO demonstrate stable dispersion with improved dielectric breakdown strength and superior thermo physical properties like thermal conductivity, viscosity and stability. An appreciable augmentation in AC breakdown voltage (BDV) is observed compared to the state-of-the-art boron nitride (BN) particles. This enhancement in BDV is elucidated by the role of the greater surface area of Maxwell-Garnet ‘oil-sheet’ interfacial region of the 2D morphology in charge trapping perspective. The faster rate of heating and cooling along with noteworthy enhancement in thermal conductivity is due to the interfacial heat transfer via 2D nanoadditives prompting good phonon transport which agrees with Maxwell's forecasts. Addition of 2D nanofiller at diluted concentration exhibits better stability and high thermal efficiency compared to its particle counterpart. Hence, 2D nanofillers are better choices for next generation transformer oil nanofluids, due to their high surface area, lower filler fraction and better stability.
LabInform: A Modular Laboratory Information System Built From Open Source Components
Authors: Biskup Till
Published: March 2022

A framework for reproducible data analysis is only half the battle if it comes to reproducible research. Additional essential requirements are a way to safely store both, raw data and metadata and a method to uniquely refer to a dataset or any piece of information. Such unique identifier is fully independent of the actual place the information referred to is stored and does not change over time. Additionally, numeric IDs for samples and alike come in quite handy. A knowledge base and an electronic lab notebook, both based on wiki software and thus easily accessible requiring only a web browser and connection to the intranet, complete the system. Overarching design rules are simplicity, robustness and sustainability, focussing on small-scale deployment of the system retaining compatibility with future developments and community efforts. Key aspects in setting up the system are its use of well-proven open-source tools combined with maximal modularity, resulting in a low entry threshold and allowing to implement and develop it along the way of focussing on actual research.
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Authors: Prakash Gnana
Published: March 2022

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Authors: Prakash Gnana
Published: March 2022

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A New Book on Historiography and Source Studies of Siberia
Authors:   Institute of Russian History RAS, Yurganova I. I.
Published: March 2022

Review of the book “Essays on Historiography and source studies of the History of Siberia of the Empire era (18th – early 20th centuries)”.
Pelos silêncios das Tisanas, de Ana Hatherly
Authors: Araujo Rodrigo da Costa
Published: March 2022

A poesia e a obra de arte, nos dinamismos que lhes são inerentes, instituem um espírito de crítica e um afã interpretativo, em busca de um redimensionamento de sua criatividade. O objetivo dessa crítica assume um questionamento da própria realidade que a obra/poesia procura representar e influenciar. Assim também são os traços delicados do livro de poesias Tisanas, da artista plástica, poeta, romancista, ensaísta e tradutora portuguesa, Ana Hatherly (1929-2015).
Caracterización de agentes de consumo energético en el sector residencial del Ecuador basada en una encuesta nacional y en los sistemas de información geográfica para modelamiento de sistemas energéticos
Authors: Moya Diego , Copara Dennis , Amores Jorge , Muñoz Espinoza Manolo , Pérez-Navarro Ángel
Published: March 2022

El sector residencial es un ejemplo de los retos que se presentan al momento de modelar la heterogeneidad del sistema energético en búsqueda de la evaluación de la política energética. Algunas de las características que influyen en la oferta y demanda de energía del sector residencial son el tipo de consumo, el ingreso de los hogares, la composición familiar, el tipo de vivienda, la zona climática de residencia, entre otras.
El objetivo de esta investigación es caracterizar los agentes de consumo energético en el sector residencial del Ecuador. Para lograrlo, en este artículo se presenta una metodología que combina una encuesta nacional (en línea y puerta a puerta) con sistemas de información geográfica (SIG). La encuesta permite definir las principales motivaciones, objetivos de inversión y método de decisión de los agentes al momento de renovar o mantener tecnologías energéticas del hogar. Para esto, se ha clasificado a los agentes con base en su nivel de ingresos. Los SIG permiten localizar espacialmente a los agentes y tener una estimación sobre la población que pertenece a cada agente por el nivel de ingreso. Los resultados se presentan por nivel de ingreso para cada grupo de agentes y se geolocalizan caracterizándolos de forma espacial. Se determina los atributos cuantitativos de cada agente con el fin de ser utilizados en modelación de sistemas de energía.
Pengaruh Independensi, Pengetahuan Keuangan, dan Gender Komite Audit Terhadap Ketidakpatuhan Pengungkapan Keuangan (Studi Kasus Pada Perusahaan Publik yang Mendapat Teguran Publik Oleh Bursa Malaysia Tahun 2014-2020)
Authors: Nurliani Dinda , Icih Icih
Published: March 2022

This research aims to determine the influence of independence, financial knowledge, and gender audit committees on non-compliance with financial disclosure. The independent variables in the study were the independence, financial knowledge, and gender of the audit committee. The study sample represents 19 companies that were publicly reprimanded by Bursa Malaysia in the period 2014-2020. Sampling method using purposive sampling method. Data analysis methods use logistic regression methods. The results of this study showed that the independence, financial knowledge, and gender of the audit committee had no effect on the non-compliance of financial disclosures. However, if assessed simultaneously the variables of independence, financial knowledge, and gender of the audit committee affect the non-compliance of financial disclosure.
ANALISIS PENERAPAN SISTEM INFORMASI PEMERINTAH DAERAH (SIPD) PADA BADAN PENGELOLA KEUANGAN DAN ASET DAERAH (BPKAD) KOTA MEDAN
Authors: Nasution Muhammad Irfan , M.Si Nurwani
Published: March 2022

SIPD or local government Information System is an information system used in medan city government as a regional development planning system, regional financial system, as well as other local government systems, including the system of coaching and supervision of local government. However, the application of SIPD, especially in Medan, has not been carried out properly because of the quality of the system that is still lacking, in addition to the lack of efficiency in terms of time or the short time needed to conduct technical guidance causes many SKPD not yet accustomed to using SIPD. The purpose of this research is to find out how sipd implementation in Medan.. Research method used is descriptive research using qualitative approach. Based on the results of the research that has been carried out, it shows that the Medan City BPKAD has used the Regional Government Information System (SIPD) application to carry out the policies needed to carry out various activities which are programs from the Medan city government. and Based on the information obtained, the Regional Government Information System (SIPD) functions to contain the regional development planning system and regional financial system, as well as other regional government systems, including the regional government guidance and supervision system.
The sleep problems diagnosed among children with autistic spectrum disorder (ASD).
Authors: Sehar Ashraf  , Taimoor Hassan  , Sana Saeed  , Sidra Siddique  , Amina Tahir  , Zahid Hussain
Published: March 2022

Objective: To find the sleep problems in children who are diagnosed with Autism Spectrum Disorder between the age ranges from 3 to 12 years. Study Design: Cross-sectional Observational study. Setting: Department of the Developmental Pediatrics Children Hospital Lahore and Department of Occupational Therapy, Rising Sun, Lahore. Period: February 2017 to November 2017. Material & Methods: This study included 300 children who were diagnosed with ASD having sleep problems between ages 3-12 years. All other children were excluded. Data was collected by using Albany sleep problem scale. The sample size was determined by utilizing WHO Software for test size assurance in wellbeing considers. Results: Results demonstrated that majority of the kids presented with different sleep disorders such as (83%) of the children took a lot of time to sleep. Moreover, (43.2%) of the children depicted continuous awakening during night time. (63.4%) of the kids faced Respiratory problems. (53%) children showed restlessness during sleep. Furthermore, (83.3%) of the children remained consciousness during sleep. Conclusion: Study concluded that most habitually sleep issues in ASD kids are nodding off, fretful rest, not falling stay in own bed, take an hour to sleep, kicking legs and successive enlightenments. Less commonly sleep problems were sleep strolling, sleep talking, and resistance to go in bed, excessive sleep-in day screams uproariously.
İŞ-AİLE ZENGİNLEŞMESİNİN YAŞAM TATMİNİ, KARİYER TATMİNİ VE İŞ YÜKÜ FAZLALIĞI ALGISINA ETKİSİ: ISPARTA İLİ BANKA ÇALIŞANLARI ÜZERİNE BİR ARAŞTIRMA
Authors: OKUDUR SABUNCU Betül , ATİLLA Gaye
Published: March 2022

Bu çalışma iş-aile zenginleşmesinin, yaşam tatmini, kariyer tatmini ve iş yükü fazlalığı algısına etkisini ölçmeyi hedeflemektedir. Araştırma Isparta il merkezindeki banka çalışanlarının tamamını kapsamaktadır. Araştırmada anket yöntemi kullanılmış, veriler kolayda örnekleme yoluyla elde edilmiştir. Çalışmaya 200 banka çalışanı katılmıştır. Araştırmada Carlson vd. (2006) tarafından geliştirilen iş-aile zenginleşmesi ölçeği’nin Kaçmar vd. (2014) tarafından oluşturulan kısa formu kullanılmıştır. Yaşam tatminini ölçmek amacıyla Diener vd. (1985), kariyer tatmini için Greenhaus vd. (1990) ve iş yükü fazlalığı için Imosili (1985) tarafından geliştirilen iş yükü fazlalığı ölçeği kullanılmıştır. Bununla birlikte cinsiyet, medeni durum, çocuk sayısı, kurum türü gibi bazı demografik sorulara yer verilmiştir.

Araştırmada regresyon analizi, korelasyon analizi ve bağımlı değişkenin demografik özelliklere göre farklılık gösterip göstermediğini ölçmek üzere t testi uygulanmıştır. Toplanan verilerin analizinde SPSS 22.0 programından yararlanılmıştır. Araştırma sonucunda, iş-aile zenginleşmesinin; kariyer ve yaşam tatmini ile pozitif, iş yükü fazlalığı ile negatif yönde ilişkili olduğu görülmüştür. Regresyon analizine göre, işten aileye zenginleşmenin kariyer tatmini, yaşam tatmini ve iş yükü fazlalığı algısını etkilediği, aileden işe zenginleşmenin de kariyer tatminini, yaşam tatminini ve iş yükü fazlalığı algısını etkilediği görülmüştür. Ayrıca iş-aile zenginleşmesinin, banka personelinin eşinin çalışma durumuna, çalıştığı kurumun türüne, yapısına ve çalıştığı birime göre farklılık gösterdiği sonucuna ulaşılmıştır.
KIRGIZİSTAN BURANA'DAKİ (BALASAGUN) KÜLTÜR VARLIKLARININ DURUMU
Authors: AYKAÇ Razan
Published: March 2022

Özet: Burana (Balasagun), V- XI yüzyıllar arasında İpekyolu’nun önemli şehirlerinden biri olmuştur. Şehir X. yüzyılda, Karahanlıların hâkimiyetine geçtikten sonra, Orta Çağ Türk-İslam kent dokusuna uygun olarak yeniden inşa edilmiştir. Buna göre; etrafı surla tahkim edilmiş dış kale, şehristanda Cuma Camisi, pazar yerleri, mahalleleri ve mahalle camileri, medreseleri, türbeleri, hamamları, dükkânları, sivil konutları ile iç kaleden oluşan bir kent olduğu anlaşılmaktadır. Karahanlı dönemi Orta Çağ Türk-İslam şehir dokusunu yansıtan ilk örnek olması açısından Burana (Balasagun) şehri oldukça önemlidir.

Şehrin Cuma Camisi’nin minaresi olan Burana Minaresi, mahalle camisi olan Burana Cami ayrıca I, II ve III no.lu türbelerde XIX ve XX. yüzyılda sondaj çalışmaları yapılmıştır. Kısmı tamir de geçiren bu yapılar plan, süsleme ve İslami dönem kent dokusunu yansıtması açısından öncü yapılardır.

1976 yılında Kırgız Hükümeti tarafından Burana (Balasagun) şehri ören yeri olarak devlet korumasına alınmış, burası Açık Hava Müzesi özelliği kazanmıştır. Başta şehirdeki eserler olmak üzere çevredeki müzelik eserler burada sergilenmektedir. Eserler arasında; Burana Minaresi (Cuma Camisi’nin minaresi), Burana (Mahalle) Camisi ayrıca I, II ve III no.lu türbeler, petroglifler, balballar ile İslami dönem mezar taşları yer almaktadır.

Bu makalede ilk Türk-İslam devleti olan Karahanlıların başkenti Burana (Balasagun) şehri ve içindeki eserler kent dokusu bağlamında ele alınmıştır.
Effect of probiotics on the formation of intestinal microbiocenosis and feed digestibility in broiler chickens
Authors: Sidorenko S.V. , Ryzhkova G.F.
Published: March 2022

This work was devoted to the influence of probiotics "Vetom 4" and "Zoonorm" in broiler chickens ration on the formation of intestinal microbiocenosis: on its quantitative and qualitative composition as well as on the feed digestibility and body weight dynamics of chickens. The studies show that probiotic preparations optimize the composition of the intestinal microbiota, increasing the content of representatives of normoflora: bifidobacteria and lactobacilli and reducing the content of pathogenic and conditionally pathogenic microflora: staphylococci, enterococci and BSCP. For example, the use of probiotic "Vetom 4" increased the amount of bifidobacteria by 1.09 Lg CFU/g, lactobacilli - by 0.98 Lg CFU/g, reduced the percentage of staphylococci, enterocococci and BSCP relative to all groups of determined bacteria. At the same time, because of the balance experiment, there was an increase in the digestibility of feed nutrients relative to the control group counterparts. Digestibility of organic matter increased by 2,38 %, crude protein by 2,45%, crude fat by 1,37%, percentage of nitrogen taken with feed by 2,5%, percentage of calcium by 3,53%. When probiotic "Zoonorm" was added to the diet, the content of lactobacilli increased by 1,77 Lg CFU/g, bifidobacteria - by 1,36 Lg CFU/g, while the percentage of staphylococci, enterocococci and BSCP decreased. Digestibility coefficients were also increased: organic matter by 3.6%, crude protein by 2.38%, crude fat by 1.06%, percentage utilization of nitrogen taken with feed by 2.25%, percentage utilization of calcium by 3.26%. In addition, by weighing the broiler chickens individually, we found higher dynamics of growth of body weight of chickens, which at the end of the experiment was 301 g more than the control values by adding probiotic "Vetom 4" to the diet and 230 g more when "Zoonorm" probiotic was added to the diet.
Epizootic situation with invasive diseases in Kursk region
Authors: Suvorova V.N. , Payukhina M.A.
Published: March 2022

The article analyzes the data for five years, from 2017 to 2021, the most common invasive diseases of agricultural and domestic animals. It was noted that in cattle, the extensiveness of infestation for fasciolosis decreased from 4.5% to only 0.5%, for dictyocaulosis from 2.9% to 0.2%, while strongylatosis became more frequent by 0.7% and trichocephalus by 1.2%. It was found that in small ru-minants dictyocausalosis occurred less frequently than in cattle. The rate of inva-sion by fasciolosis was decreased by 4%, by strongylosis - by 0,1%, the rate of trichocephalosis decreased from 1,9% to 0,2%. The incidence of ascariasis among pigs decreased from 0.55% to 0.2%, esophagostomosis from 0.2% to 0.1%. Among horses a marked decrease in the extensiveness of invasion by parascarido-sis from 8.7% to 8.3% is noted. The extensiveness of invasion of dogs has been determined as for dirofilariosis during five years it decreased from 3% to 0.9%, for toxocariasis and trichocephalosis from 61.7% to 15.7% and for pyroplasmosis it became more frequent by 26.1%. The region has established close work between the veterinary service and scientists of the Department of Veterinary Medicine, and courses are held annually to im-prove the skills of livestock workers. A system for monitoring and prophylaxis of carnivore dyrofilariosis has been developed jointly. The system offers routine, tar-geted monitoring of canine blood tests for dirofilariasis in the amount of at least 200 samples per year per subject. On a monthly basis, animal disease control sta-tions and inter-district veterinary laboratories submit information to the rehabilita-tion unit on the number of dogs inspected and found to be infected, with the names and addresses of their owners. The results are used to eliminate the source of infes-tation by microfilarial treatment of identified infested animals.
A study of vocabulary in oral expressions of Indonesian students learning Turkish as a foreign language in terms of diverse variables
Authors:   Bursa Uludag University, Turkey, Eroglu Suleyman
Published: March 2022

One of the essential characteristics of the human being as social existence is his ability to communicate with his environment. There are many ways for people to communicate. However, the most preferred form of communication in interpersonal relations was primarily speaking. Effective use of speaking skills can be said to be possible if individuals have sufficient vocabulary. This research aims to examine the vocabulary of Indonesian students learning Turkish in their oral expressions in terms of various variables. The research study group consists of 25 Indonesian students who have completed Turkish language education at the C1 level and are studying in different faculties and departments of Bursa Uludağ University. The primary data of the research consists of interviews with Indonesian students who learn Turkish as a foreign language. A semi-structured interview form was used to collect data in the study. The vocabulary of Indonesian students in their oral expressions was obtained by calculating the number of words they used once, the number of different words they used, and the total number of words they used. SCP 4.07 and SPSS 25.0 package programs were used in the numerical analysis of the data. Data were analyzed with Mann-Whitney U and Kruskal-Wallis tests. In line with the findings, it was concluded that the vocabulary in the oral expressions of Indonesian students who learn Turkish shows a significant difference in the number of languages they know other than Turkish and the frequency of reading newspapers.
Lecturas desde las Cartas Anuas. Contribuciones al estudio de los jesuitas en Hispanoamérica
Authors: Nájera Nájera Guillermo Antonio , Crespo María Fernanda
Published: March 2022

La presencia de los jesuitas en América fue uno de los componentes clave en la formación y consolidación de la sociedad colonial. Su influencia y trascendencia histórica es uno de los factores que, bajo múltiples mediaciones, tienen profunda significación en el espacio latinoamericano actual. Este libro reúne contribuciones al conocimiento y la reflexión acerca de la rica historia jesuítica de los siglos XVI al XVIII. En él se presentan estudios de alta especialización, completamente originales, que aportan nuevo conocimiento en sus campos específicos. Investigaciones realizadas principalmente mediante la utilización de las denominadas litterae annuae, las cartas anuas, informes periódicos particularizados y complejos de la actividad jesuita, dirigidos a los generales de la Compañía de Jesús en Roma.
La construcción de la paz
Authors: Anichiarico González Angélica María , López Santamaría Ramsés , Tapia Vega Ricardo
Published: March 2022

La construcción de la paz es una obra que nos conduce a la reflexión sobre diversos temas relativos a la cultura de la paz, su concepción, promoción y algunas líneas de acción para su realización, desde diversas cosmovisiones, que en un eje nos permite mirar ópticas nacionales (México y Colombia), y en otro, ópticas multidisciplinares (derecho, pedagogía, sociología, política, administración, contabilidad, economía, agroecología, salud, arquitectura, psicología y filosofía), constituyendo un producto policromático que se aproxima muy bien a la realidad, que lejos de ser unidimensional es, más bien, siempre multidimensional. Este libro es también la conjunción de los ánimos profesionales de investigadoras e investigadores de la Universidad Autónoma del Estado de Morelos (México) y de la Corporación Universitaria Autónoma del Cauca (Colombia), que acrisola y da evidencia de la posibilidad del trabajo académico transdisciplinar y transfronterizo, coordinado en éste caso por Ricardo Tapia Vega, Angélica María Anichiarico González y Ramsés López Santamaría. La obra se compone de 20 trabajos de investigación que han sido arbitrados con el método de pares ciegos, divididos en dos bloques nacionales: mexicano y colombiano. Se presenta en coedición internacional bajo los respetables sellos de las universidades antes referidas.
Analisis Technological Pedagogical Content Knowledge Terhadap Kemampuan Menyusun Perangkat Pembelajaran Matematika Daring Calon Guru SD
Authors: Amrina Zulfa , Anwar Vita Nova , Alvino Joni , Sari Syafni Gustina
Published: March 2022

Peningkatan penggunaan teknologi dalam pembelajaran matematika di Sekolah Dasar menuntut calon guru SD untuk harus menguasai teknologi, pengetahuan konten materi dan kemampuan pedagogi. Tujuan dari penelitian ini adalah untuk menganalisis technological pedagogical content knowledge (TPACK) terhadap kemampuan menyusun perangkat pembelajaran matematika daring calon guru SD. Sampel pada penelitian merupakan mahasiswa PGSD Universitas Bung Hatta yang sedang mengambil mata kuliah pembelajaran matematika II pada semester genap tahun 2020/2021. Desain penelitian yang digunakan adalah mixed method embedded experimental model. Instrumen perlakuan adalah enam buah satuan acara perkuliahan (SAP), angket TPACK yang terdiri dari TK, CK, PK, PCK, TCK, TPK dan rubrik penilaian perangkat pembelajaran matematika. Hubungan antara variabel TPACK dengan kemampuan menyusun perangkat pembelajaran dilihat menggunakan SEM AMOS. Dari hasil penelitian terdapat peningkatan kemampuan TPACK mahasiswa calon guru SD sebelum dan sesudah diberikan perlakuan. Kemudian diperoleh hasil dari confirmatory factor analysis bahwa kemampuan TPACK sangat dipengaruhi oleh kemampuan menyusun RPP. Dari hasil analisis secara keseluruhan diperoleh hasil bahwa calon guru yang mempunyai kemampuan TPACK yang tinggi akan berpengaruh positif terhadap kemampuan menyusun perangkat pembelajaran matematika secara daring.
Co-creating research integrity education guidelines for research institutions
Authors: Labib Krishma , Evans Natalie , Pizzolato Daniel , Aubert Bonn Noémie , Widdershoven Guy , Bouter Lex , Konach Teodora , Langendam Miranda , Dierickx Kris , Tijdink Joeri K.
Published: March 2022

Background: To foster research integrity (RI), research institutions should develop a continuous approach to RI education, addressing various target groups. To support research institutions achieve this, we developed RI education guidelines together with RI experts and research administrators, exploring similarities and differences in recommendations across target groups, as well as recommendations about RI education using approaches other than formal RI training. Methods: We used an iterative co-creative process. After exploring the literature, we conducted four half-day online co-creation workshops with 16 participants. In the first two workshops, participants generated ideas for guidelines’ content focusing on different target groups and various approaches to RI education, based on which we developed first drafts of the guidelines. Participants in the third and fourth workshop refined those drafts. We next organized a working group which further prioritized, reorganized, and optimized the content of the guidelines. Results: We developed four guidelines on RI education focusing on a) bachelor, master and PhD students; b) post-doctorate and senior researchers; c) other RI stakeholders; as well as d) continuous RI education. Across guidelines, we recommend mandatory RI training; follow-up refresher training; informal discussions about RI; appropriate rewards and incentives for active participation in RI education; and evaluation of RI educational events. Conclusions: Our work provides experience-based co-created guidance to research institutions on what to consider when developing a successful RI education strategy. Each guideline will be offered as a distinct, publicly available tool in our toolbox (https://sops4ri.eu/toolbox/) which institutions can access, adapt and implement to meet their institution-specific RI education needs.