bluuebunny/crossref_metadata_2025 huggingface dataset:
Screening of anti-inflammatory activity of 4.5-dihydroisoxazol-5-carboxamide (PAR-2 inhibitors) based on formaldehyde oedema model among white lab rats
Authors: Korsakov Mikhail K. , Fedorov Vladimir N. , Smirnov Nikolay A. , Shetnev Anton A. , Leonova Olga V. , Volkhin Nikita N. , Andreyev Aleksandr I.
Published: January 2024

Introduction: Rheumatoid arthritis (RА) is an immune-inflammatory disease intrinsic to up to 1.0% of the world’s population. Standard drugs for RA therapy are basic medications, glucocorticoids and non-steroid anti-inflammatory drugs, which often only ease or hinder the course of disease, not curing the patient completely. Also, on the average 20-50 % of patients are unresponsive to treatment, allergic to the prescribed drugs or find them ineffective. That is why medications with a different mechanism of action are being widely researched, some of them being antagonists of proteinase-activated receptors (PAR-2).

Materials and Methods: The inflammatory process was reproduced by injecting a 2% solution of neutral formalin in a volume of 0.1 mL under the aponeurosis of the posterior left foot. A total of 84 white rats were used in the experiment. Diclofenac sodium was administered as a reference drug.

Results and Discussion: An experiment on researching the impact of 5 samples of derivatives of 4.5-dihydroisoxazol-5-carboxamide on formalin oedema development among rats showed that the compound R001, compared with other substances studied, differs in the late onset of the therapeutic effect when ingested; the restoration of the foot volume to the initial level occurs only after the introduction of R005, R004 and R002. R005 to a greater extent than other compounds prevents the development of edema and has greater therapeutic efficacy than diclofenac sodium both with intragastric administration and subcutaneous injection.

Conclusion: All five compounds in question showed anti-inflammatory activity, with the spectrum not so unequivocal both in qualitative and quantitative values.
New Emerging Spiritualism Lifestyle: A Case Study of Erphan Halghehgroup
Authors: Jabrian Nafiseh , Zolfalifam Jafar
Published: January 2024

The present article is a descriptive and qualitative research on the life style of the newly emerging spiritualist group of Erphan Halgheh, which was conducted on 14 continuous and discrete members of this group with semi-structured interviews. The results show that participation in this collection has created significant changes in their lifestyles and has changed their consumption patterns to a God-worshipping spiritual approach.
Estimation of HIV Prevalence among the Female Population in South India: A Bayesian Approach
Authors: Arumugum Elangovan , Joshua Vasna
Published: January 2024

Introduction: The HIV Sentinel Surveillance (HSS) conducted by National AIDS Control Organization (NACO) is the predominant data source for HIV estimations in India. While the HSS targets the key populations at risk of HIV infection, the National Family Health Survey (NFHS) measures the community- based HIV prevalence. Improvised HIV estimates in India were attributed to the HIV prevalence data obtained from the NACO-HSS and NFHS.
Methods: Bayesian analysis was performed to determine the state-level prevalence of HIV among females in seven South Indian States. The analysis involved plotting the prior, likelihood, and posterior distributions, facilitating a visual assessment of the data. The HIV prevalence among females calculated from the NFHS (2015-16) survey data was used for prior distributions. HIV prevalence among pregnant women obtained from the HIV Sentinel Surveillance 2019 was used for likelihood. Bayesian analysis was performed using the R programming (RStudio 2022.02.0). A posterior probability distribution was obtained using the prior distribution and the likelihood by applying the Bayes theorem. Graphical representation was achieved through R's plotting functions. Kerala and Pondicherry were not included in the analysis due to zero or very low prevalence reported in both NFHS and HSS.
Results: The Bayesian estimates of HIV prevalence among females were 0.38 % [95% CI:0.29 - 0.47] in Andhra Pradesh, 0.28 [95% CI:0.23 - 0.35] in Karnataka, 0.27 [95% CI:0.20 - 0.34] Odisha, 0.27 % [95% CI:0.19 - 0.36] in Telangana and 0.19 [95% CI:0.15 - 0.24] in Tamil Nadu.
Conclusion: Bayesian techniques present a versatile and robust strategy for modelling and analysing HIV- related data, offering a flexible and powerful approach to data analysis.
Coincidence of nasopalatine duct cyst and dentigerous cyst: a rare case report
Authors: Sadeghian Ali , Taheri Anita , Bakhshaei Pedram
Published: January 2024

Dentigerous cyst is one of the most common odontogenic cysts of the jaw that slowly grows around an unerupted tooth crown. Nasopalatine duct cyst is a non-odontogenic common jaw cyst. Co-oc- currence of nasopalatine duct cyst and dentigerous cyst in the same location of the same jaw is ex- tremely rare. Odontogenic and non-odontogenic cysts occurring simultaneously in non-syndromic patients is rare. The lesions must be fully extracted by surgery. We report the treatment procedure of a patient suffering from this rare phenomenon.
Comparison of Imipenem Prescription Model in Imam Khomeini and Taleghani Educational Center of Urmia
Authors: Shiva Afshin , Divanbeigi Maryam
Published: January 2024

Introduction: Drug utilization evaluation (DUE) studies are designed to evaluate the rational use of drugs. Our purpose in this study is to evaluate the pattern of Imipenem, a broad-spectrum antibiotic used in different parts of Imam Khomeini and Taleghani Educational Center of Urmia.
Method and material: This is a cross-sectional and retrospective study. The study was conducted by reviewing medical records of 200 admitted patients who received Imipenem during March 2016 to 2017.
Results: In the study Imipenem was prescribed most frequently for intra-abdominal infection in 71 cases (35.5%), 41cases (20.5%) respiratory infection, 31 cases (15.5%) urinary tract infection, 25 cases (12.5%) skin infection, 15 (7.5%) cases septicemia infection, 7 (3.5%) cases bone and neutropenic infection, endocarditis infection were reported in 3 cases (1.5%). The highest incidence was related to intra-abdominal infections. 61% of Talehgsni hospital patients and 46% of Imam Khomeini hospital patients received Imipenem less than a week. The used dose in all patients was between one to four grams per day and the frequency of use was not correct in 7% of Taleghani hospital patients and 23% of patients in Imam Khomeini hospital.
Conclusion: Some AB combination was proved to be inappropriate to the guidline consedering the indication or the microorganism to be covered. It is necessary to take action to improve prescribing habit in order to reduce the unnecessary usage of antibiotic thus enhance rational antibiotic use.
Implementing Accreditation Standards in Academic Medical Programs is Necessary to Trust Higher Education: The Experience of Two Academic Programs at Qassim University, Kingdom of Saudi Arabia
Authors: Hassan Mohieldein Abdelmarouf
Published: January 2024

Background: Quality assurance (QA) is becoming more critical in higher education (HE) worldwide. Quality in HE can be managed by QA, quality improvement, and quality control. This systematic review demonstrates the benefits of QA and academic accreditation in HE by examining the National Commission for Academic Accreditation and Assessment (NCAAA) accreditation standards and two accredited academic programs at Qassim University (QU) in the Kingdom of Saudi Arabia (KSA).
Methods: Elton B. Stephens Company (EBSCO) e-library was used to collect and retrieve literature from December 2022 to January 2023. Only English-language full-text papers were reviewed and cited.
Results: To assure medical education quality and encourage healthcare workforce confidence, medical educational institutions must be overseen by a QA system, such as a formal accreditation system. The World Federation of Medical Education set “Trilogy” global standards for quality improvement in medical education. The ambitious “Vision 2030” of KSA invests a large percentage of its Gross Domestic Product in education to address the significant challenges of educational quality management. The sole statutory organization in KSA that evaluates and accredits all public and private HE institutions and programs is the National Commission for Academic Accreditation and Assessment (NCAAA). The NCAAA’s accreditation standards are generally acknowledged as good practice in HE worldwide and have been adapted to KSA higher education’s special circumstances. NCAAA has recently granted accreditation to two academic programs offered by the College of Applied Medical Sciences, QU.
Conclusion: Accreditation promotes “added value” under the win-win-win “WWW” paradigm, where stakeholders win first, then the program, and finally the community.
Clinical and Demographic Patterns of Pulmonary Tuberculosis in Patients with Diabetes Mellitus: Impact of Diabetes Mellitus on Patient
Authors: Vyas Yagnang , Leuva A. T.
Published: January 2024

Background: Tuberculosis (TB) is a communicable infectious disease and one of the leading causes of death. Until the coronavirus pandemic, tuberculosis was the leading cause of death from a single infectious agent, more than HIV/AIDS. Due to urbanization and rapid social and economic development, there is a rapidly increasing diabetes mellitus (DM) epidemic and India has the second largest number of DM patients in the world. There are around 74.2 million DM cases and 40.1 million people with impaired glucose tolerance. Tuberculosis is more common in low- and middle-income countries. The increasing trend of the two diseases poses a major challenge for the tuberculosis control program.
Methods: The main goal of this research was to investigate clinical and demographic patterns of pulmonary tuberculosis in patients with DM. It is a prospective, observational, in-hospital study. We studied 165 PTB patients associated with DM who were at least scanty/1+ positive on smear or had Mycobacterium TB sputum CBNAAT detected.
Results: Of the 165 patients, 127 PTB-DM patients were male and 38 were female. The most common symptom was cough, which occurred in 164 (99.4%) patients. Fever was the second most common symptom in 152 (92.1%) patients and anorexia was the third most common symptom, occurring in 119 (72.1%) patients.
Conclusion: The majority of patients were from IPD 88 (54%), suggesting that PTB–DM cases have a more severe and complicated presentation. Male patients are affected more frequently than female patients. People in the age group 31–60 years often suffer from PTB–DM. Cough, fever, and anorexia are the most common symptoms, while chest pain and breathlessness are more common in the older age group. The history of PTB in DM patients is also of concern as the present study shows that there is a possible association with relapse or reactivation of PTB as well as drug resistance of PTB.
Application of R.E.N.A.L Nephrometry Score in Planning Type of Surgery and Predicting Complications in RCC Patients in Gezira Hospital
Authors: Shakir Ali Yousif Muzafr , Shakir Ali Yousif Ahmed , Gamal Abdelmagid Marwa , Mohammed Osman Yassin , Mahjoub Taha Sami
Published: January 2024

Background: Adult renal cell carcinomas account for 80–85% of all renal tumors, making them the most common primary renal tumors. As a method for categorizing renal masses by anatomical characteristics, R.E.N.A.L score is suggested to study the effect on surgical approach in addition to perioperative outcomes and complications.
Methods: A cross-sectional prospective hospital-based study enrolled 48 RCC patients in GHRDS in the period between September 2020 and September 2021. Data regarding demographics, histological subtypes, surgical approach, intraoperative and postoperative complications were collected. Based on R.E.N.A.L score, the complexity of renal tumors is grouped into low, moderate, and high.
Results: The study sample size was 48. Twenty-five participants (52.1%) were men with a mean age of 51 years. Most cases had clear cell RCC 22 (45.8%) and papillary RCC 19 (39.6%). Thirty-nine (81.5%) patients underwent radical nephrectomy (flank incision [extraperitoneal] in 32 [82.1%] and midline incision [transperitoneal] in 7 [17.3%]), and 9 (18.5%) patients underwent partial nephrectomy. One-third of the patients 15 (31.2%) had intraoperative complications and 7 (14.6%) had postoperative complications. All intraoperative and most postoperative complications were associated with radical nephrectomy (P = 0.001). According to complexity, 21 (43.8%) patients had moderate complexity, 15 (31.2%) high complexity, and 12 (25%) low complexity.
Conclusion: Most RCC patients had moderate complexity and were subjected to radical nephrectomy. High complexities were linked to the decision of radical nephrectomy, and intraoperative and postoperative complications. More prospective research with large sample size and multi-centered studies is essential to ensure the generalizability of study findings.
An Updated Review on Rheumatoid Arthritis (RA): Epidemiology, Pathophysiology, Diagnosis, and the Current Approaches for Its Treatment
Authors: Ashiq Kanwal , Ashiq Sana , Mobashar Aisha , Abid Farah , Yasmeen Anam , Shehzadi Naureen , Tanveer Khan Muhammad , Hussain Khalid
Published: January 2024

Rheumatoid arthritis (RA) is a systemic self-inflicted inflammatory disease that primarily affects middle-aged women. Globally, 1% of people live with RA. This review aims to provide updated information on the different aspects of RA, including its epidemiology, pathophysiology, diagnosis, treatment, and management. A web-based literature search was conducted through various databases, including PubMed, Google Scholar, and Science Direct, to identify the most relevant studies. Epidemiological studies have suggested that the prevalence and occurrence of RA have remained inconsistent across geographical areas in different periods. Many factors such as age, gender, inheritances, and environmental exposure can contribute to the severity of the disease. The acute form of RA usually presents with pain, and if left untreated, it can result in joint deformities and influence a patient’s quality of life (QoL). RA diagnosis is usually based on the manifestation of pain with inflammation. Currently, many therapeutic strategies are available for the cure of RA. The management of daily routine activities is required with treatment to curtail the damage, avoid future deformities, and ultimately minimize the aching trouble of the patient.
The Intervention of Anchovy (Stokphorus commrsouli) Calcium Extract Could Elevate Calcium Levels during Pregnancy and Give Birth and Promote Bone Development: An in vivo Study
Authors: . Supriyana , Siregar Irma HY , Sunarjo Lanny , Aryati Endah , Fatmawati Dina
Published: January 2024

Background: During pregnancy, calcium deficiency has become a frequent phenomenon. Calcium intake is essential for supporting maternal and fetal health to maintain calcium homeostasis and promotes bone formation. Anchovy is a high calcium source from marine. The anchovy diet impact on fetal development during pregnancy is inconclusive. Therefore, Anchovy Calcium Extract (ACE) effect on calcium homeostasis and bone formation was studied. Methods: Female Sprague Dawley rats were grouped into three: without ACE administration, with ACE administration prior to mating until two weeks post-labor and with ACE administration after pregnancy confirmation until two weeks post-labor. Blood calcium levels and bone hardness were measured. Result: ACE improved maternal’s and offspring’s calcium levels. ACE also provided adequate blood calcium levels during pregnancy, labor and breastfeeding. In addition, ACE improve maternal bone firmness but has no significant effect on its offspring. In conclusion, ACE has excellent potential as a dietary supplement to promote adequate calcium requirements for maternal and infant health.
Prevalence and molecular characterization of Multidrug-Resistant ESBL-Producing E. coli in commercial poultry
Authors: Sakthikarthikeyan Sengamani , Sivakumar Mani , Manikandan Rajendran , Kumar Periyathambi Senthil , Kumar Veerapandian Suresh , Malmarugan Shanmugasamy , Prabhu Manimuthu , Ramakrishnan Vijayaragavan
Published: January 2024

Background: Rural poultry farmers are gradually changing from the backyard poultry production to intensive production, which made poultry more vulnerable to diseases and lead to indiscriminate use of antimicrobials in poultry production. As per OIE, FAO and WHO, multiple spread antimicrobial resistant pathogenic bacteria are a serious global human and animal health problem. Hence the study has been carried out to know the antimicrobial resistance status of poultry in Tirunelveli, Tamil Nadu, India. Methods: The study was aimed to find the occurrence of extended spectrum beta lactamases (ESBLs) producing E. coli from poultry origin. Caecum samples from the broiler (n=180), desi chicken (n=180) and Japanese quail (n=180) were processed for the isolation and phenotypic identification of ESBL E. coli. The isolates were tested for antimicrobial susceptibility test and characterization of ESBL and virulence genes done by PCR. Result: On phenotypic confirmation of ESBL producing E. coli by combined disk diffusion test (CDDT), a total of 9.63% samples were positive for extended spectrum beta lactamase producer (ESBL). Multi drug resistance (MDR) was observed in 38.23% of the broiler isolates, 27.27% and 57.14% in desi chicken and Japanese quail isolates, respectively. All the phenotypically confirmed ESBL producing E. coli isolates (n=52) were positive for uspA gene by PCR confirming the isolates as E. coli. The overall presence of the blaTEM gene was 57.69%, with broiler isolates having the highest prevalence of 67.47%, followed by desi chicken 36.36% and Japanese quail 42.85%. In contrast, the blaSHV gene was found in only 17.64% of the broiler isolates, but none were positive for the blaCTXM and blaOXA-1 gene.
In vitro Evaluation of Nerium oleander Leaf Extract against Sarcoptes scabiei var. cuniculi Mite Isolated from Naturally Infested Rabbits
Authors: Murshed Mutee , Mares Mohammed M. , Aljawdah Hossam M.A. , Al-Quraishy Saleh
Published: January 2024

Background: Infestation of the mite Sarcoptes scabiei var. cuniculi is one of the most frequent skin diseases in rabbits all over the world. Disease is characterized by intense pruritus, alopecia, erythema, scales and crusts around the head, neck, trunk, feet, ears, nose and genitals, resulting in hypertensive reactions, considerable losses in body weight and productivity causing significant economic losses in rabbit production. Methods: This study is aimed to evaluate the efficacy of Nerium oleander extract against S. scabiei var. cuniculi mite in vitro. Acaricidal bioassay, a dipping method was conducted on mites isolated from naturally infested rabbits. PBS and ivermectin were used as the negative and positive controls, respectively. In addition, three different concentrations of extract (100, 200 and 400 μg/ml) weretested at different periods and changes over time in the viability of mites were registered for (0.5, 1, 2, 4 and 8 hours). A chemical assay was performed via GC-MS to investigate the presence of several anticipated active chemical compounds in Nerium oleander leaf extract. Result: The results showed that the extract had high efficacy in killing mites at 100%, 78% and 49% and ivermectin 91%, respectively, for 8 hours. The results indicate that Nerium oleander possesses effective compounds as a valuable therapeutic method for treating scabies. Further studies are needed to determine the precise active chemicals present in Nerium oleander leaf extract and their modes of action and application in vivo.
In vitro Sporulation, Oocysticidal Sporulation Inhibition of Eimeria papillate and Cytotoxic Efficacy of Methanolic Extract of Thymus daenensis Leaves
Authors: Maodaa Saleh N. , Al-Shaebi Esam M. , Hailan Waleed Ali Qaid , Abdel-Gaber Rewaida , Alatawi Afaf , Alawwad Sarah A. , Al-Quraishy Saleh
Published: January 2024

Background: Thymus daenensis is a phenol-rich species of the Thymus genus that possesses many biological and pharmaceutical activities. Methods: This study used five groups of TDLE extract (50, 100, 200 and mg/mL). Distilled water and mebendazole (10 mg/ml) were used as negative and positive controls. Five worms of similar size were placed in each Petri plate, together with the extract test solution (20 mL). The present work aims to study the phytochemical profiling, evaluation of anticancer properties and in vitro oocysticidal activity of methanolic T. daenensis leaves extracts (TDLE). Results: Infrared spectroscopy (FT-IR) of TDLE proved eleven different active classes of chemical compounds. The extract is characterized by higher phenolic contents (250.5±2.7 mg/g of gallic acid) and flavonoids (25±0.3 mg/g of quercetin). Also, TDLE showed moderate cytotoxicity against breast cancer cell lines (MCF-7) and lung cancer cell lines (A549) using MTT assay with LC50 attributed to 388.66±3.5 ìg/ml and 354.33±2.5 ìg/ml, respectively. The in-vitro study revealed that TDLE concentrations of 300 mg/ml caused significant suppression of Eimeria. papillata oocysts sporulation and increased percent of sporulation inhibition compared to the other commercial products which showed different levels of sporulation. Our findings indicate that TDLE has anticoccidial activity, which encourages the conduct of numerous In vivo investigations to find an effective treatment.
Variability and stability of essential oil composition in Ukrainian hop varieties
Authors: Protsenko Lidia , Janse Liliya , Koshytska Nina , Ryzhuk Serhii , Liashenko Mykola , Bober Anatolii , Gunko Sergiy
Published: January 2024

The aim of the study was to evaluate the variation in essential oil content and composition within nine distinct Ukrainian hop varieties, with a particular focus on their genetic stability and suitability for brewing applications over 11 years of their cultivation. The hydrodistillation method (Analytica-EBC 7.10) was used to evaluate hop essential oil content and gas-liquid capillary chromatography (Analytica-EBC 7.12) to discern its qualitative composition. Variability was evaluated using statistical parameters. The essential oil content across the studied varieties spanned from 0.51 to 2.58 ml/100 g of dry hop cones. The highest content was measured in the bitter-aroma variety with a special aroma – Ruslan. The predominant essential oil components, including myrcene, caryophyllene, humulene, and farnesene, collectively constituted 70.0–84.2% of the total amount. The aroma varieties displayed myrcene content typical for European varieties (with the level up to 56.2% in the Ruslan variety). Farnesene content exhibited significant variation ranging from 0.3 to 17.6% with the highest content in Saaz-type varieties (Klon 18, Zlato Polissya, and National) and the bitter type Promin variety. Humulene content ranged from 13.2 to 32.6%. Among all studied varieties, Alta displayed the least variability for all parameters evaluated (Cv = 15.2%). This study underscores the genetic basis of essential oil composition in hops, emphasizing its potential as a biochemical criterion for identifying hop breeding varieties. The study revealed, that despite annual fluctuations, the essential oil content and composition remained within passport data declared for the variety. The findings provide valuable insight into a sustainable cultivation and optimal utilization of hops in the brewing industry.
Caracterisasion Geochimique des Deblais du Substratum de la Baie du Banco, Abidjan, Basse Cote d‘Ivoire
Authors: Ferdinand Yao Diby , Jean Paul Assale Fori , Jonas Alla Amani , Bruno Digbehi Zeli
Published: January 2024

L’étude géochimique réalisée s’est éffectuée sur les déblais du substratum de la baie du Banco situé au Sud-est du bassin sédimentaire côtier de la Côte d’Ivoire. Cette étude vise à caractériser le substratum de la baie du Banco à partir des éléments chimiques ainsi que la détermination des paléoconditions des environnements de dépôt. La spectrométrie par fluorescence à rayon x (XRF) a permis de déterminer  les éléments majeurs ainsi que des éléments traces présents dans les lutites noirâtres du substratum de la baie. Les éléments majeurs identifiés sont par ordre décroissant le Silicium (45,33 %), le Fer (35,56 %), l’Aluminium (9,24 %), le Potassium (2,31 %), le Calcium (2,22 %), le Titane (2 ,15 %), le Chlore (2,04 %) et le Phosphore (1,12 %). L’analyse géostatistique a permis de mettre en évidence de fortes corrélations entre la matière organique et le fer réduit (Fe 2+), l’étain (Sn), l’arsenic (As) et le soufre (S). Le substratum de la baie du Banco est caractérisé par une forte concentration en soufre variant de 12475 à 75752 ppm et une bioproductivité primaire plus importante en profondeur qu’en surface. Les éléments traces U, V et Mo ont permis d’identifier un milieu euxinique à interface eau-sédiment en subsurface du substratum (0- 32 m) tandis qu’en fin de forage (78-80 m), on distingue un milieu suboxique à anoxique. Ces différents résultats ont permis de caractériser le substratum de la baie du Banco.

 

The geochemical study was carried out on cuttings from the Banco Bay bedrock in the southeastern part of the Côte d'Ivoire coastal sedimentary basin. The study aimed to characterize the Banco Bay bedrock based on chemical elements and to determine the paleo conditions of the depositional environments. X-ray fluorescence spectrometry (XRF) was used to determine the major and trace elements present in the blackish lutites of the bay bedrock. The major elements identified were, in descending order, Silicon (45.33%), Iron (35.56%), Aluminium (9.24%), Potassium (2.31%), Calcium (2.22%), Titanium (2.15%), Chlorine (2.04%) and Phosphorus (1.12%). Geostatistical analysis revealed strong correlations between organic matter and reduced iron (Fe 2+), tin (Sn), arsenic (As), and sulfur (S). The Banco Bay bedrock is characterized by high sulfur concentrations ranging from 12475 to 75752 ppm, and higher primary bioproductivity at depth than at the surface. Trace elements U, V, and Mo identified an euxinic environment at the water-sediment interface in the subsurface of the bedrock (0-32 m), while at the end of the borehole (78-80 m), a suboxic to anoxic environment was distinguished. These results have enabled us to characterize the bedrock of the Banco Bay.
Rendement et Composition Chimique du Tourteau de Tetracarpidium conophorum (Müll. Arg.) Hutch. & Dalz Produit par Pression Mécanique et Hydrodistillation
Authors: Ntsoumou M.V. , Adzona P.P. , Ndoulou T.M , Banga Mboko H.
Published: January 2024

Les tourteaux, principales sources de protéines végétales, sont les sous-produits de l’usinage des graines traitées pour en extraire l’huile selon les techniques de pressage à chaud et d’extraction par les solvants. L’objectif de ce travail était de produire le tourteau de Tetracarpidium conophorum et évaluer son rendement et sa composition chimique par deux techniques de production : la presse mécanique et la méthode d’hydrodistillation. Le rendement du tourteau à partir du broyat a été de : 73,63% et 72,50% respectivement pour la presse mécanique et l’hydrodistillation. (P> 0,05). Quant à la composition physico-chimique du tourteau, les différences significatives ont été observées (p<0,05) en faveur de la méthode par presse mécanique notamment sur la MS (91,10% contre 97,63%) ; lipides (10,78% contre 14,46%) ; protéines brutes (24,63% contre 43,75%) ; calcium (1,94% contre 3,17%) ; phosphore (0,46% contre 0,85%). La faible composition chimique du tourteau en protéines brutes du tourteau produit par hydrodistillation par rapport à celle du tourteau produit par pression mécanique suscite la maitrise de la température de l’eau.    

 

Oil cakes are by-products of seeds treated to extract oil by using many ways. The objective of the present study was to produce the oil cake of Tetracarpidium conophorum and to evaluate its yield and their chemical composition by two techniques of production mainly the pressure in cold and the hydrodistillation methods. There was no significant difference in yield in both techniques used. (P> 0, 05). Whereas, chemical composition was significantly higher in oil cake produced by using pressure in cold than by hydrodistillation mainly (p<0,05) the DM (91,10% versus 63%); lipids (10,78% vs 14,46%); crude proteins (24,63% vs 43,75%); calcium (1,94% vs 3,17%); phosphorus (0,46% vs 0,85%). The lower chemical composition of the crude protein oil cake produced by hydrodistillation compared to that of the oil cake produced by cold pressures may be due to the uncontrolled temperature of the water during the process of delipidation.
Scaling to Technological Readiness Levels 6 in the Bio-Environmental Laboratory
Authors: Scotti Adalgisa
Published: January 2024

In this work, we present the Bio- Environmental Engineering scaling laboratory; that is located in Los Reyunos, Regional Development Technology Center. Its objective is the scaling of concept proof to pilot or prototype test for technology transfer suitable in real environments. We suggest the laboratory as an automatized Technological Demonstrator that allow us to adapt the work conditions making possible that the technology scope the degree of innovation with TRL 6. That scale test allows to know the parameters to apply in the territory mainly about ph, Eh, inlet flow, bioremediation system, kind irrigation, relationship between cycles.
Pemahaman Moderasi Beragama dan Tingkat Toleransi pada Milenial Muslim di Perkotaan
Authors: Putra Ilham Mirzaya
Published: January 2024

Penelitian ini bertujuan untuk menganalisis pemahaman moderasi beragama di kalangan milenial muslim di perkotaan provinsi Sumatera Utara. Penelitian ini merupakan jenis penelitian deskriptif, komparatif, serta korelatif dengan menggunakan pendekatan kuantitatif. Sampel dalam penelitian ini berjumlah 672 muslim milenial yang berasal dari 7 kota di Sumatera Utara. Pengumpulan data menggunakan kuesioner, observasi, dan dokumentasi. Analisis data menggunakan analisis Deskriptif, Anova Satu Arah, dan Regresi Sederhana. Hasil penelitian menunjukkan bahwa 1) Kaum milenial muslim di perkotaan Provinsi Sumatera Utara telah memahami moderasi beragama; 2) terdapat perbedaan yang signifikan dalam memahami moderasi beragama antar kota di Sumatera Utara; 3) tingkat toleransi generasi muslim milenial di perkotaan Provinsi Sumatera Utara adalah di tingkat Anerkennung dan Achtung. 3 kota berada pada level Achtung, sedangkan 7 kota lainnya berada pada level Anerkennung; dan 4) pemahaman moderasi beragama berpengaruh positif signifikan terhadap toleransi.
Pengaruh Rasio Keuangan Early Warning System terhadap Tingkat Solvabilitas pada Perusahaan Asuransi yang Terdaftar di Bursa Efek Indonesia
Authors: Prayogi Feri , Inayah Nurul , Daulay Aqwa Naser
Published: January 2024

Penelitian ini bertujuan untuk menguji pengaruh rasio likuiditas, rasio beban klaim, dan rasio pertumbuhan premi terhadap tingkat solvabilitas yang diproksikan dengan Risk Based Capital (RBC). Adapun populasi dalam penelitian ini adalah 16 perusahaan asuransi yang terdaftar di Bursa Efek Indonesia (BEI). Sampel yang digunakan berjumlah 10 perusahaan yang diperoleh dengan menggunakan metode purposive sampling. Data yang diperoleh dari laporan tahunan perusahaan yang diperoleh dari website resmi BEI yaitu www.idx.co.id dengan metode analisis data menggunakan uji statistic deskrptif, uji regresi linear berganda, uji t parsial, uji f simultan dan uji koefisien determinasi. Hasil penelitian menunjukkan bahwa: Likuiditas berpengaruh positif dan signifikan terhadap risk based capital artinya menunjukkan bahwa likuiditas memberikan kontribusi yang besar terhadap risk based capital; Rasio beban klaim berpengaruh positif dan signifikan terhadap risk based capital artinya menunjukkan bahwa rasio beban klaim memberikan kontribusi yang besar terhadap risk based capital; Pertumbuhan premi berpengaruh positif dan signifikan terhadap risk based capital artinya menunjukkan bahwa pertumbuhan premi memberikan kontribusi yang besar terhadap risk based capital. Berdasarkan Uji F, likuiditas, rasio beban klaim, dan pertumbuhan premi berpengaruh positif dan signifikan terhadap risk-based capital.
Komunikasi Politik dan Pemilu 2024: Upaya Pemerintah Daerah Kabupaten Bima Menuju Pemilu yang Bermartabat
Authors: Tasrif Tasrif
Published: January 2024

Penelitian ini bertujuan untuk menganalisis upaya Pemerintah Daerah Kabupaten Bima dalam memastikan pemilu yang bermartabat adalah langkah yang tak terhindarkan dalam memperkuat demokrasi di tingkat lokal dan nasional. Penelitian ini adalah penelitian kualitatif, yang menggabungkan pendekatan deskriptif dan eksploratif.  Adapun Teknik Pengumpulan Data dilakukan melalui wawancara, observasi Partisipatif kemudian Analisis Dokumen. Hasil penelitian menunjukan bahwa Pemerintah daerah Kabupaten Bima harus mengakui peran krusial komunikasi politik dalam Pemilu 2024 dan berusaha untuk menerapkannya secara efektif. Dengan menggabungkan transparansi, partisipasi masyarakat, dan pendidikan politik, pemilu di Kabupaten Bima dapat berjalan dengan integritas dan memberikan hasil yang mewakili keinginan rakyat. Selain itu Pemerintah juga berperan sentral dalam dalam menciptakan penyelenggaraan pemilu yang adil, meningkatkan partisipasi masyarakat, menyediakan informasi yang jelas, menjaga keamanan, dan mempromosikan etika pemilu, dan memastikan bahwa Pemilu 2024 di Kabupaten Bima berjalan dengan baik dan sesuai dengan prinsip-prinsip demokrasi yang kuat.
Pengembangan Karakter Tanggung Jawab Siswa Melalui Penciptaan Peraturan dan Dukungan Siswa
Authors: Syarofah Syarofah , Aziz Rahmat , Ratnasari Dewi
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pengaruh aktivitas kelas terhadap karakter tanggung jawab siswa di dua sekolah yang berbeda yaitu MTs (Malang) dan SMP (Lamongan). Pendekatan penelitian yang digunakan yaitu pendekatan kuantitatif, dengan menggunakan teknik  multisage random sampling yaitu siswa kelas VII, VIII dan IX dengan jumlah keseluruhan responden sebanyak 207. Teknik pengumpulan data menggunakan observasi, kuesioner (angket), wawancara, dan dokumentasi. Adapun teknik analisis data yang digunakan dalam penelitian ini diantaranya uji normalitas, uji linearitas, uji analisis statistik deskriptif dan uji regresi simultan dan parsial. Hasil penelitian menunjukkan bahwa terdapat pengaruh yang signifikan antara aktivitas kelas dan tanggung jawab siswa, yang ditunjukkan dari nilai uji regresi dengan tingkat signifikansi sebesar 0,000 < 0,05 yang artinya model regresi dapat dipakai untuk memprediksi pengaruh variabel aktivitas kelas (X) terhadap variabel tanggung jawab (Y). Juga dilakukan uji normalitas dengan menggunakan uji kolmogrov-smirnov test diperoleh hasil signifikansi 0,200 yang berarti lebih besar dari taraf sig 0,05 sehingga terdistribusi normal. Selanjutnya dilakukan uji linear dan diperoleh hasil sebesar 0,024, maka data tersebut linear karena lebih besar dari taraf sig 0,05. Maka dapat disimpulkan terdapat hubungan linear signifikan antara variabel aktivitas kelas (X) dan variabel tanggung jawab (Y).
Efektivitas Media Scramble dalam Meningkatkan Fokus Pembelajaran Siswa pada Mata Pelajaran PAI dan Budi Pekerti
Authors: Aziz Amirul , Astutik Anita Puji
Published: January 2024

Penelitian ini bertujuan untuk  mencari solusi terhadap tantangan kesulitan belajar bagi siswa yang berada di SMP Muhammadiyah 5 Ngoro melalui Media Scramble. Penelitian ini menggunakan teknik Penelitian Tindakan Kelas (PTK) yang melalui  siklus dengan setiap siklusnya berisikan 4 tahap yaitu perencanaan, pelaksanaan, observasi, refleksi. Jika ditelusuri lebih lanjut Media Pembelajaran Scramble , dapat meningkatkan pemahaman literasi pada siswa SMP Muhammadiyah 5 Ngoro dengan ditunjukkan ketika Pra-tindakan skor rata-rata 60,66 dengan presentase kelulusan 0%, meningkat pada Siklus 1 skor rata-rata 64,11 dengan presentase kelulusan tetap diangka 0%. Setelah melalui proses evaluasi dilanjutkan siklus 2 mendapatkan skor rata-rata 74,66 dengan presentase kelulusan 55,56%, sebagaimana komitmen penulis diawal bahwasannya untuk minimal kelulusan adalah sebesar 77,78% dari jumlah siswa kelas VII SMP Muhammadiyah 5 Ngoro  maka siklus  disempurnakan dan memberikan hasil skor rata-rata 81,56 dengan presentase kelulusan menjadi 100%.
POPULISMO E MELODRAMA: a intimidade em vídeo nas redes sociais de Jair Bolsonaro
Authors: Lepri Adil Giovanni , Baltar Mariana
Published: January 2024

Este artigo busca refletir sobre o papel da retórica melodramática em mobilizar efeitos de uma intimidade partilhada, consolidando sensações de proximidade que sustem projeções afetivas e empáticas e, com elas, ajudando a formar uma base de apoio pautada nesta ordem de engajamento passionais. Nesse sentido, focaremos nos audiovisuais das redes sociais de Jair Bolsonaro para demonstrar como uma retórica do perseguido é agenciada fortalecendo, através de uma gestão melodramática do discurso político, um regime de passionalidade central para a sustentação do populismo.
USOS E GRATIFICAÇÕES DA VIOLÊNCIA NA MÍDIA: o que sabemos sobre os motivos para a exposição e seus efeitos no receptor
Authors: Marques Carriço Ferreira Raquel , Oliveira Santana Dhione
Published: January 2024

Estudos constatam o crescimento quantitativo e “qualitativo” da violência nas mídias, como o que aponta que 80% dos conteúdos são violentos[1]. Mas mensagens violentas tornam sua audiência também violenta? Essa indagação tem sido objeto de investigação de tradições que privilegiam os “efeitos” sobre o comportamento do indivíduo. Para o possível efeito, entretanto, as motivações do receptor, bem como suas características particulares ao selecionar conteúdos violentos devem ser examinadas. Nesse sentido, realizamos uma revisão de literatura  dos estudos de Usos e Gratificações que exploram o desenvolvimento do comportamento violento. Para além das características fundamentais para desenvolver tais comportamentos, categorizamos os fatores para a exposição à violência: 1. Hábito; 2.Gerenciamento do Humor; 3.Integração Pessoal e 4.Interação Social. Muito embora os motivos e a exposição à violência das mídias sejam consistentes com o desenvolvimento de comportamentos agressivos, esses não são os predecessores mais significativos associados a tal comportamento.

 

[1] Ver WEAVER (2011).
RECONFIGURAÇÕES DO TRABALHO E DA IDENTIDADE DE JORNALISTAS: reflexões com base em pesquisa no período de pandemia de Covid-19
Authors: Figaro Roseli , Molini João Augusto , Pachi Filho Fernando Felício , Nonato Cláudia
Published: January 2024

Este artigo traz uma reflexão acerca do quese delineia como identidade profissionaldos jornalistas. A análise parte de umapesquisa realizada pelo CPCT-ECA/USP em2021, e cujo corpus é composto porrespostas dos profissionais de todos osEstados, que trabalham no jornalismo e emáreas correlatas. A relação das respostasválidas apontou que mais da metade dosrespondentes declarou se identificar comojornalista; informação que vemacompanhada, ao longo da pesquisa, peladeclaração da função e da atividade querealizam como jornalistas, razão que noslevou a essa reflexão. Para tanto,apresentamos os dados da pesquisa,discutimos o que se entende por identidadeprofissional, vinculada a valores e, por fim,fazemos algumas ponderações à título deconclusão.
SOCIAL MEDIA FOR PROMOTION AND COMMERCIALIZATION IN FAMILY FARMING: a resource application perspective
Authors: Rossi Scalco Andrea , Fracari de Souza Amanda , Hengler Côrrea Bernardo Cristiane , Bernardo Roberto , Satolo Eduardo Guilherme
Published: January 2024

Family farming provides food diversityworldwide. If, on the one hand, there is itsproductive efficiency, within the scope ofthe management of diverse cultures, on theother hand, there is the challenge in thepromotion and commercialization of familyfarming products. This article seeks to,through a Systematic Literature Review (SLR)and the use of the StArt tool, analyze theresearch published in the databases Scopusand Web of Science, so as to verify the useof social media for promotion andcommercialization in family farming. Theresults indicate that the use of social mediain family farming is beneficial, bringingpositive results, however, it lacks incentives,investments, and attention from publicpolicies.
GRAMÁTICA	DA PAQUERA ONTEM E HOJE EM GURUPI (TO)
Authors: Anjos Ana Carolina Costa dos , Batista Lívia dos Santos , Lima Paulo Roberto Albuquerque de , Lima Alessandra Gomes Duarte de
Published: January 2024

A discussão sobre as gramaticas de relacionamentos e regimes de desejo são temas transversais à debates da e na sociedade contemporânea. Neste artigo, buscamos discutir o que há em comum e as possíveis mudanças nas demonstrações de interesse afetivo-amoroso-sexual entre pessoas jovens, em dois momentos distintos (1999 e 2019), no município de Gurupi, especificamente narrado em dois suportes, a saber: secção Recadinhos do jornal local Cocktail e perfil no Instagram Crush Gurupi. Para tanto, valemo-nos dos pressupostos metodológicos da Análise Crítica da Narrativa de Motta (2013). Compreendemos que há a existência de modelos de relacionamento e regime de desejos ‘amor romântico’ e ‘amor neoliberal’/líquido, os quais são apresentados por meio de narrativas com léxicos tácitos de cada época.
O EU APAIXONADO: A escolha e o significado da atividade de lecionar li e a afinidade com a língua e a profissão
Authors: Costa Rosemeire Parada Granada Milhomens da , Andrade Karylleila dos Santos
Published: January 2024

Este artigo se insere no campo de estudos da Linguística Aplicada LA e tem como objeto de pesquisa discutir o auto-olhar do profissional de Língua Inglesa LI, ou seja, o delineamento de suas identidades, tendo em vista o cenário da globalização pós- moderna. Trata-se de um estudo de caso de natureza qualitativa no qual foram entrevistadas quatro professoras de uma escola de inglês de curso livre da cidade de Gurupi, estado do Tocantins, nomeadas como P1, P2, P3 E P4. O objetivo geral é conhecer o profissional de escolas de idiomas e compreender como elas lidam com as próprias identidades de professoras de LI e com a responsabilidade cultural e social de ensinar uma língua estrangeira. O suporte teórico para este trabalho foi ancorado em teóricos como: Bauman (2005), Celani (2006), Leffa (2012), Rajagopalan (2014) entre outros. Os resultados demonstraram que as participantes apresentaram uma relação íntima de admiração pela língua, além disso, identificamos que questões sociais e/ou ideológicas que permeiam as identidades dessas profissionais são temas pouco discutidos e relativamente novos para elas, por conseguinte, causando uma precária reflexão em suas práxis pedagógica.
NOTAS METODOLÓGICAS PARA UMA ANÁLISE DA SEMÂNTICA GLOBAL DE ENUNCIADOS JORNALÍSTICOS
Authors: Cabra Scabin Nara Lya
Published: January 2024

Este artigo discute as possibilidades e potencialidades da transposição de conceitos da Análise do Discurso (AD), nomeadamente, a noção de “semântica global do discurso” de Dominique Maingueneau (2008), a corpora compostos por materiais jornalísticos. Para tanto, investiga a cobertura de jornais brasileiros sobre a o dia internacional da mulher entre 1978 a 2018. As reflexões apontam para a consolidação de características manifestas em diferentes planos dos enunciados jornalísticos sobre a condição da mulher, sugerindo certa estabilização recente nos modos de enunciar sobre o tema, e destacam a pertinência de proposições da AD Francesa a estudos do Jornalismo.
THE CONSUMPTION OF FOOD PRODUCTS IN SHORT CHAINS: the case of social and reputational labels
Authors: Rodrigues João Augusto , Scalco Andrea
Published: January 2024

There have been an increasing demand for products of short food supply chains, which enable consumers to identity of the product and its origin, which is established through information transmitted by labels and certifications. This article analyzed consumers’ motivations for demanding products with labels of local or social reputation. A survey was conducted with consumers in São Paulo. Descriptive statistics was used to raise the consumer's profile and their motivations for consuming these products. The consumer's motivations are related to aspects of the place of origin, as well as the benefits of acquiring it, without considering price aspects.
THE HYBRID WORK OF JOURNALISTS AND THE REIFICATIONS OF COMMUNICATIVE CAPITALISM
Authors: Souza Rafael Bellan Rodrigues de
Published: January 2024

Hybrid work emerges as a new modality formany journalists. This article seeks to reflecton how the digital gears of communicativecapitalism invade the spheres of productionand reproduction of journalists' lives on aglobal scale, demonstrating how forms ofremote work, consolidated in the pandemiclaboratory of technological experiments,intensify processes of reification in everydaylife. of the workers. The encounter betweenreified productive activity and fetishisticconsumption seems to hold hands in thedigital territory of capital metabolism. Thehybrid work of journalists expresses thecontradictions of this approach.
ATENDIMENTO EDUCACIONAL ESPECIALIZADO PARA ALTAS HABILIDADES: um estudo de caso de pensamento computacional
Authors: Corrêa Lacerda Thiago , De Carvalho Ribeiro Neyse , Da Silva Soares Ivani , Arruda Dias Kátia
Published: January 2024

Estudantes com Altas Habilidades/Superdotação constituem um número expressivo nas classes escolares, embora sejam invisibilizados pela comunidade escolar. Com o objetivo de expandir as reflexões acerca dessa temática, esse trabalho apresenta um estudo de caso sobre um adolescente diagnosticado com Altas Habilidades e que apresenta Pensamento Computacional. Trata-se de uma pesquisa bibliográfica e qualitativa, em que foi aplicado ao adolescente um questionário contendo sete perguntas e um campo para observações. Os resultados obtidos apontam para um dado sensível de falta de Atendimento Educacional Especializado para os alunos com Altas Habilidades/Superdotação nos espaços escolares. Isso nos leva a concluir que estamos perdendo a possibilidade de encontrar, estimular e desenvolver talentos e potenciais nesses estudantes.
A INOVAÇÃO E INTERNACIONALIZAÇÃO NO CONTEXTO DA PEÇA ARTESANAL DE CAPIM DOURADO
Authors: Pacheco Flavio Augustus da Mota , Rebouças Porto Júnior Francisco Gilson Rebouças
Published: January 2024

Este estudo teve como objetivo analisar o comportamento de pequenas empresas produtoras de capim-dourado em relação à inovação e internacionalização. A pesquisa segue uma abordagem quantitativa e é considerada uma investigação exploratória e descritiva com pesquisa de campo, utilizando um questionário estruturado com perguntas fechadas. A unidade de análise para este estudo foi um grupo de 16 artesãos. O instrumento foi aplicado digitalmente e formulado através do Google Forms, e o pré-teste envolveu 7 artesãos. Este estudo conclui que, devido ao baixo grau de inovação entre os artesãos, a exportação tem sido negativamente impactada. Além disso, à luz da literatura revisada, infere-se que, dado o baixo nível de comportamento inovador, a exportação entre artesãos é frágil.

Palavras-chave: Inovação; Internacionalização; Artesanato; Capim Dourado.