bluuebunny/crossref_metadata_2025 huggingface dataset:
Testosterone as a biomarker of colorectal cancer in the South Indian population
Authors: Younis Mohd , Gezici Sevgi , Sudershan Amrit , Digra Sanjeev Kumar , Gupta Ashma , Meyyazhagan Arun , Kumar Parvinder , Anand Vijaya
Published: October 2023

Colorectal cancer (CRC) is a highly life-threatening disease associated with a significant mortality rate. It has been proposed that testosterone levels may play a role in predisposing individuals to such devastating conditions. Testosterone primarily governs the maturation of the male reproductive system while also exerting physiological effects in both genders. In the present study, we investigated testosterone levels in CRC patients among the South Indian population. Blood samples were collected in the hospitals in Tamil Nadu, South India, and a cohort of healthy controls was selected for comparative analysis. A total of 130 subjects participated in the study, consisting of 65 CRC patients and an equal number of healthy controls. Approximately 7 mL of blood was collected from each subject for radioimmunoassay. The results of radioimmunoassay on the blood samples were analyzed using SPSS to assess differences between discrete and continuous data variables. Chi-square and t-tests were conducted for statistical evaluation. CRC patients exhibited significantly (P < 0.0001) reduced mean testosterone levels (06.68 ± 2.15 nmol/L) compared to controls (22.54 ± 8.85 nmol/L). Further stratification by smoking status revealed that non-smoker CRC patients had lower testosterone levels (06.81 ± 2.21 nmol/L) than non-smoking controls (10.15 ± 2.48 nmol/L), with a statistically significant difference (P < 0.0001). Adjusting for alcohol consumption, CRC patients displayed decreased mean testosterone levels (06.31 ± 2.30 nmol/L) compared to controls (07.96 ± 2.45 nmol/L), and this difference was found to be significant (P < 0.022). These findings support the notion that reduced testosterone levels serve as a critical risk biomarker in the pathogenesis of CRC.
Essential roles of BRD4 in cancer: DNA damage, transcription regulation, and signal transduction
Authors: Sun Sylvia Y.
Published: October 2023

During cancer progression, bromodomain and extra-terminal (BET) families regulate chromatin and recruit enzymes that are associated with chromatin regulation to control gene expression. The bromodomain-containing protein 4 (BRD4) plays an important role in DNA damage repair, nuclear factor kappa B (NFκB) signaling, interaction with c-Myc, and transcription regulation of genes essential in carcinogenesis, as well as links transcription at enhancers and genes to regulate enhancer transcription. The colocalization of BRD4 with enhancer and promoter-proximal gene regions enables the elongation activation at enhancer genes. The inactivation of BRD4 has been demonstrated to inhibit cancer development, corroborating BRD4 as a promising therapeutic target. In addition, small-molecule inhibitors targetting functional domains of BRD4 are under investigation for their potential therapeutic applications in cancer and other diseases. This review presents an overview of BRD4 function and its dysfunction in cancer progression, as well as discusses how the potential of BRD4 as a therapeutic target.
Dynamic-passive correction of hallux valgus and associated static foot deformities
Authors: Dygut Jacek M. , Strąk Joanna , Detyna Jerzy , Piwowar Monika W.
Published: October 2023

Purpose

The paper presents, the effects of hallux valgus correction and coexisting static deformities of the foot (transversely-plano and plano-valgus foot) obtained with a new dynamic-passive method of treatment.

Methods

The study involved 50 patients; 26 with full big toe correction after the passive correction grip (group I) and 24 with big toe correction requiring additional passive abduction (group II). The patients regularly performed exercises using the designed device according to the planned schedule. The progress of the correction was assessed by a medical examination and additional tests.

Results

Results: The cross-sectional area [cm2] of the abductor hallucis muscle in three-time points among I and II groups of patients with the Hallux Valgus was measured based on MRI images. The STIR examination showed among other the abductor hallucis muscle edema after exercises with the DPc device were carried out. It evidences that exercises with the new device activate the muscle. Alignment of the big toes of both feet in groups I and II were obtained with a statistically significant result (p<0.05). The percentage progression of correction for HV and I/II IM was calculated.

Conclusions

Based on the new correction approach the alignment of the big toe phalanges and the remaining toes was obtained. The passive setup of the tendons with their distal inserts at the level of the big toe phalanges to the correct path of their course with the withdrawal of articular subluxations was obtained. Simultaneously, the big toe's passive correction was dynamically consolidated through a specially selected set of exercises.\
The impact of fatigue on static balance in people with chronic ankle instability
Authors: Kowalczyk Małgorzata , Truszczyńska-Baszak Aleksandra
Published: October 2023

Purpose

The aim of the study was to assess static postural stability under fatigue in subjects with chronic ankle instability – “coopers” in comparison to healthy controls.

Methods

We conducted a prospective study on a group of 60 young, physically active subjects, who we divided into 3 groups: I- 14 subjects with unilateral ankle instability, II - 15 subjects with bilateral ankle instability, 31 healthy subjects, without ankle instability. The fatigue trial was based on modified Short-Term Fatigue Protocol. Static stabilography was performed with the use of HUR platform.

Results

Results showed an increase in the value of COP trace length after fatigue test in study population I. The level of COP trace length Z before fatigue was significantly lower than after fatigue. Subjects from study population I had higher levels of COP trace length Z in comparison with the control group. The main effect for the group also proved to be significant. Study population I had higher levels of COP trace length Z in comparison with the control group. For the measurement after fatigue there was significant difference only between the study population I and the control group.

Conclusions

1. The incidence of structural ankle instability was not correlated with functional instability. Subjects with ankle instability, or “copers”, had good functional levels, enabling them to perform sports activities.

2. “Copers” had weakened proprioception in static stabilography tests.
Balance Control via Tactile Biofeedback in Children with Cerebral Palsy
Authors: Argunsah Hande , Yalcin Begum
Published: October 2023

Purpose

Children with Cerebral Palsy have limitations in utilizing neural information to perform smooth movement and maintain balance during walking. This study aimed to develop a wearable sensor that tracks balance continuously and provides haptic biofeedback to its user through real-time vibration stimulus to assist patients with balance and postural control impairments such as cerebral palsy.

Methods

Twelve children with cerebral palsy and 12 age-matched typically developed children used the sensor during walking at a self-selected speed. The lower extremity joint kinematics, center of mass, and spatial-temporal parameters were recorded with Xsens MVN during “with” and “without” biofeedback conditions.

Results

The sensor did not disturb healthy gait. Pearson Correlation Coefficient and Root Mean Square Error techniques showed that biofeedback regulated the gait parameters and trunk stability of the CP group when biofeedback was given. The extended stance percentage (without BF: 73.91% ± 10.42, with BF: 63.53% ± 2.99), step width (without BF: 0.20m ± 0.05, with BF: 0.18m ± 0.07), and step time (without BF: 1.55s ± 1.07, with BF: 0.73s ± 0.14) parameters decreased; similarly, cadence and walking speed increased.

Conclusions

Obtained results indicated that this wearable sensor can be integrated into the physical therapy and rehabilitation process of children with balance and postural control impairments to improve motor learning and balance control. The present findings contribute to a better understanding of the adaptation of innovative engineering applications with rehabilitation processes, which in turn could assist patients with balance impairments and facilitate their integration into society.
Analysis of Muscle Activity During Rowing Stroke Phases
Authors: Czajkowska Urszula , Świątek-Najwer Ewelina , Jankowski Ludomir
Published: October 2023

Purpose

Rowing engages large muscle groups, and EMG analysis is used to assess athletes' condition and refine sports technique. The aim of the experiment was to evaluate the muscle activation level during different phases of the rowing cycle on an ergometer.

Methods

In a study involving one professional and five amateurs, the mean EMG amplitudes from the quadriceps, gastrocnemius, biceps, and triceps brachii were analyzed during different phases of rowing. A comparison was made between the degree of muscle engagement during the exercise between the professional and inexperienced individuals, as well as among the different individuals during recordings obtained at different rowing speeds. The correlation coefficient between the values recorded using a strain gauge and the EMG amplitude recorded from the surface of the biceps and triceps brachii muscles was evaluated.

Results

The muscle activation pattern during rowing has a predictable character. A difference in the muscle activation pattern during rowing between the professional and amateurs was observed. The EMG signal is correlated with the force recorded by the resistive strain gauge only in the experienced rower at a pace of 20 and 25 cycles per minute.

Conclusions

Electromyographic analysis can be useful for assessing the correctness of rowing techniques. The activation pattern of muscles during rowing has a predictable nature. The force generated by the participants increases with an increase in rowing frequency.
Jamaican Place Names
Authors: Higman B.W. , Hudson Brian J.
Published: October 2023

B.W. Higman is Emeritus Professor of History, University of the West Indies, and Emeritus Professor of History, Australian National University. He is the author of eleven books on Caribbean history, archaeology and geography, including the award-winning publications Slave Population and Economy in Jamaica, 1807–1834; Slave Populations of the British Caribbean, 1807–1834; Jamaica Surveyed: Plantation Maps and Plans of the Eighteenth and Nineteenth Centuries; Montpelier, Jamaica: A Plantation Community in Slavery and Freedom, 1739–1912; Writing West Indian Histories; Plantation Jamaica, 1750–1850: Capital and Control in a Colonial Economy; and Jamaican Food: History, Biology, Culture. His most recent books are A Concise History of the Caribbean and How Food Made History.
George Padmore's Black Internationalism
Authors: Worrell Rodney
Published: October 2023

In George Padmore’s Black Internationalism, Rodney Worrell traces the main features of Padmore’s social and political thought. Worrell explores Padmore’s use of the ideologies of Marxism and pan-Africanism as vehicles to liberate Africa and the Caribbean from the grip of European imperialism. As an engaged Marxist revolutionary, Padmore played a leading role in the Soviet Union’s black internationalism project during the early 1930s. After he severed his ties with the Comintern, he became one of the leading pan-African activists in Britain from the mid-1930s until he migrated to Ghana in 1957, where he made his mark as a member of the International African Service Bureau, the Pan-African Federation, and in organizing the Fifth Pan-African Congress in Manchester, England, in 1945. Padmore became a major theorist of the unification of the African continent and worked assiduously to see this become a reality as Kwame Nkrumah’s advisor on African affairs. Worrell provides a sound and thorough account of Padmore’s strident anti-imperialism and radical anti-colonial critiques while simultaneously outlining his championing of self-determination. This engrossing work scrutinizes Padmore’s political praxis and illuminates his invaluable contribution to pan-Africanism and his dedication to the liberation of Africa and the Caribbean from colonial rule.
Low-Income Housing & The State in the Eastern Caribbean
Authors: Potter Robert B.
Published: October 2023

The first comprehensive analysis of housing conditions and State policies in three countries of the eastern Caribbean: Grenada, St. Lucia, and St. Vincent and the Grenadines. The study focuses on the interrelationships between the poor, low-income housing, and the policies of the State. The author concludes that 'in the realm of State housing policy and provision, the efforts of low-income groups to house themselves have been almost totally neglected as a socio-cultural resource of major importance. -Handbook of Latin American Studies, v. 57
Penatalaksanaan pada Pasien Laki-Laki Usia 50 Tahun dengan Tinea Pedis melalui Pendekatan Kedokteran Keluarga
Authors: Qanit Ismalia , Nusadewiarti Azelia
Published: October 2023

Tinea pedis merupakan infeksi jamur dermatofita yang memiliki sifat mengikis keratin di jaringan, khususnya pada kaki. Tinea pedis didapatkan pada orang dengan higien diri, lingkungan sekitar, dan perawatan kaki yang buruk. Pencegahan tinea pedis dapat dilakukan dengan cara pemakaian APD pada saat melakukan kontak dengan faktor penyebab atau memperbaiki higien diri. Tujuan penelitian ini adalah Mengidentifikasi faktor risiko, masalah klinis, serta memberi penatalaksanaan pada pasien dengan penerapan pelayanan dokter keluarga secara holistik berbasis evidence based medicine. Metode studi ini adalah laporan kasus. Data primer diperoleh melalui anamnesis dan pemeriksaan fisik. Data sekunder diperoleh dari rekam medis pasien di Puskesmas. Penilaian dilakukan berdasarkan diagnosis holistik dari awal, proses, dan akhir studi secara kuantitatif dan kualitatif. Hasil penelitian ini adalah laki-laki usia 50 tahun, datang dengan keluhan gatal dan nyeri pada kaki kanan. Gatal dirasakan sejak 1 minggu lalu. Pasien mengatakan keluhan sering berulang. Diketahui pasien seorang petani dan sering berkontak dengan air karena setiap hari selalu menggunakan sepatu tertutup dalam waktu yang lama. Pasien jarang memperhatikan kebersihan diri setelah beraktifitas.. Diketahui bahwa pasien tinggal bersama dengan 6 anggota keluarga lain dan rumah sedikit lembab. Pasien didiagnosis sebagai tinea pedis. Hasil evaluasi yang didapatkan adalah penurunan gejala klinis dan peningkatan pengetahuan pasien dan keluarganya.  Kesimpulan yaitu telah dilakukan penatalaksanaan holistik dengan pendekatan dokter keluarga pada Tn.H dengan tinea pedis yang disesuaikan dengan EBM. Intervensi yang dilakukan telah menambah pengetahuan pasien dan mengubah beberapa perilaku pasien dan keluarganya, yang ditunjukkan dengan perbaikan pada diagnostik holistik akhir.
Pengaruh Video Animasi Pencegahan Kekerasan Seksual terhadap Sikap Anak Jalanan
Authors: Suryati Suryati , Setyawan Aris , Sari Dian Nur Adkhana , Purnomosidi Faqih
Published: October 2023

Kehidupan anak jalanan di lingkungan masyarakat tidak jauh dari berbagai macam kekerasan. Anak jalanan merupakan anak yang paling rentan terhadap kekerasan seksual, terutama anak jalanan dengan jenis kelamin perempuan dan berusia dibawah 18 tahun. Kekerasan seksual seringkali  ditemui pada anak jalanan perempuan, baik ketika sedang mencari rezeki di jalanan, maupun di dalam komunitasnya sendiri atau sesama anak jalanan. Dampak kekerasan seksual tidak hanya merusak fisik melainkan merusak psikologis. Dalam penelitian ini upaya pencegahan terjadinya kekerasan seksual yang dilakukan yaitu dengan pemberian edukasi menggunakan media video animasi. Penelitian ini bertujuan untuk mengetahui pengaruh pendidikan kesehatan menggunakan media video animasi terhadap sikap tentang pencegahan kekerasan seksual pada anak jalanan di Yayasan Rumah Impian Yogyakarta. Jenis penelitian ini adalah Pra Eksperimen dan desain penelitian yang digunakan adalah One Group Pre Test-Post Test Design. Teknik sampling yang digunakan  Simple Random Sampling dan sampel dalam penelitian berjumlah 30 responden.Uji statistik yang digunakan adalah Uji Wilcoxon. Hasil uji wilcoxon didapatkan nilai ρ value 0,000 kurang dari 0,05 maka hasil tersebut dapat diartikan bahwa terdapat pengaruh yang signifikan terhadap sikap anak dalam pencegahan kekerasan seksual.
Pengaruh Pemberian Terapi Akupresur terhadap Penurunan Tekanan Darah pada Lansia Penderita Hipertensi
Authors: Yulisda Devi , Arjuna Arjuna , Permatasari Indah
Published: October 2023

Hipertensi merupakan salah satu penyakit degeneratif. Dengan bertambahnya usia, denyut jantung maksimum dan fungsi lain jantung juga berangsur menurun. Untuk provinsi kepulauan Bangka Belitung pada tahun 2020 sampai 2022 terjadi peningkatan yang sangat signifikan. Untuk wilayah Bangka Tengah pada tahun tahun 2020 penderita hipertensi sebanyak 2.608 orang di Bangka Tengah dan pada tahun 2021-2022 penderita hipertensi mencapai 5.602 orang di Bangka Tengah. Berdasarkan kasus di Puskesmas Koba berjumlah 1102 orang penderita hipertensi pada lansia. Tujuan penelitian untuk mengetahui pengaruh pemberian terapi akupresur terhadap penurunan tekanan darah pada lansia penderita hipertensi di puskesmas koba tahun 2023.Penelitian ini dilakukan dengan metode desain penelitian kuantitatif dengan metode penelitian Quasi Eksperimen dengan Pretest dan Postest with control group. Populasi dalam penelitian ini adalah pasien hipertensi di Puskesmas Koba Kelurahan Koba pada 1 tahun terakhir pada bulan desember tahun 2022. Sampel dalam penelitian ini adalah masyarakt yang tekanan darah sistolik ≥ 140 mmHg dan diastolik ≥ 80 mmHg di Puskesmas Koba.Hasil penelitian ini menunjukka bahwa tekanan darah sistolik dan diastolik pada kelompok perlakuan menunjukkan perbedaan yang signifikan dibandingkan dengan kelompok kontrol sebelum dan setelah dilakukan terapi akupresur dimana p value sistolik = 0,000 dan p value diastolik = 0,0048. Kesimpulannya ada perbedaan tekanan darah pada pasien hipertensi sesudah dilakukan tehnik akupresur.
Hubungan Motivasi Kerja dengan Kinerja Perawat dalam Memberikan Asuhan Keperawatan di Rumah Sakit Umum
Authors: Wardani Intan Kusuma , Sumarni Tri , Siwi Adiratna Sekar
Published: October 2023

Kinerja perawat adalah memberikan mutu pelayanan kepada rumah sakit yang dicapai seseorang pegawai dalam melaksanakan tugas sesuai tanggung jawab yang diberikan. Salah satu faktor yang mempengaruhi kinerja adalah motivasi kerja. Selain itu, pengaruh motivasi kerja terhadap kinerja seseorang tergantung pada banyaknya intensitas pemberian motivasi terhadap seseorang, hal ini terjadi pada pelaksanaan peran perawat sebagai pelaksanaan asuhan keperawatan. Tujuan penelitian ini adalah untuk mengetahui hubungan antara motivasi kerja dengan kinerja perawat dalam pemberian asuhan keperawatan di RSU Amanah Sumpiuh Banyumas. Desain penelitian ini menggunakan metode kuantitatif dengan pendekatan cross sectional. Populasi dalam penelitian ini berjumlah 50 responden yang seluruh perawat RSU Amanah Sumpiuh Banyumas dengan menggunakan teknik total sampling. Instrumen yang digunakan penelitian ini berupa kuesioner. Analisis data uji bivariat menggunakan uji korelasi kendall’s tau. Hasil penelitian yang diperoleh terutama sebagian besar responden berusia 23-30 tahun sebanyak 39 responden (78%), berjenis kelamin perempuan sebanyak 34 responden (68,0%), tingkat pendidikan D3 Keperawatan sebanyak 30 responden (60%) dan lama kerja 1-2 tahun sebanyak 26 responden (52%). Sebagian besar responden motivasi kerja tinggi sebanyak 31 responden (62,0%) dan kinerja perawat yang baik sebanyak 45 responden (90,0%). Berdasarkan  hasil uji korelasi kendall’s Tau diperoleh hasil p value sebesar 0.043 dengan taraf signifikan 5% yang berarti terdapat hubungan yang signifikan antara motivasi kerja dengan kinerja perawat dalam memberikan asuhan keperawatan di RSU Amanah Sumpiuh Banyumas.
Gambaran Pengetahuan Ibu Hamil Risiko Tinggi tentang Kesehatan Mental
Authors: Priyanto Rofiko Roli , Utami Tin , Ningrum Ema Wahyu
Published: October 2023

Kehamilan pada setiap perempuan memiliki risiko terjadi kehamilan dengan risiko tinggi. Salah satu sebab Angka Kematian Ibu (AKI) dan komplikasi pada janin disebabkan karena pengetahuan yang salah atau kurang pada ibu hamil risiko tinggi. Pentingnya kesehatan mental bagi ibu hamil risiko tinggi dalam mewujudkan kesehatan yang menyeluruh tidak lepas dari pengetahuan yang baik. Upaya pencegahan yang dapat dilakukan untuk menekan terjadinya komplikasi pada ibu hamil risiko tinggi adalah dengan mengidentifikasi gambaran pengetahuan ibu hamil risiko tinggi tentang kesehatan mental. Penelitian bertujuan untuk mengetahui gambaran pengetahuan ibu hamil risiko tinggi tentang kesehatan mental di Puskesmas Cilacap Utara 1. Metode penelitian ini adalah deskriptif analitik. Teknik pengambilan sampel dalam penelitian ini dilakukan dengan metode total sampling yaitu 35 responden. Ibu hamil dengan risiko tinggi yang bersedia mengisi kuesioner pengetahuan ibu hamil risiko tinggi tentang kesehatan mental yang telah diuji validitas di Puskesmas Cilacap Utara 2 dengan hasil uji validitas 12 item pernyataan pada 30 responden yang mempunyai nilai r hitung >0,374 r tabel dan hasil uji reliabilitas menggunakan Cronbach’s Alpha dengan nilai sebesar 0,826. Hasil penelitian menunjukan sebagian besar usia responden adalah 20-35 tahun sebesar 77%, Paritas pada responden adalah primipara sebesar 40%, dan multipara 40%, Usia kehamilan pada responden adalah masa kehamilan trimester 3 dengan angka 46%, Jenis kehamilan risiko tinggi yang ada di Puskesmas Cilacap Utara 1 mencapai angka sebesar 66%, Pengetahuan Ibu Hamil Risiko Tinggi di Puskesmas Cilacap Utara 1 dengan kategori cukup sebesar 70%.
Asuhan Keperawatan Pola Nafas Tidak Efektif dengan Balloon Blowing pada Pasien Chronic Kidney Disease
Authors: Prayulis Ita , Susanti Indri Heri
Published: October 2023

Penyakit ginjal kronis atau Chronic Kidney Disease (CKD) merupakan salah satu masalah kesehatan utama di dunia adanya peningkatan kasus secara signifikan dan menjadi masalah kesehatan serius. Sesak nafas sering kali ditemukan pada penderita Chronic Kidney Disease (CKD). Jika ginjal terganggu, maka proses pembentukan sel darah merah di sumsum tulang juga akan ikut terganggu yang dapat menyebabkan jumlah oksigen yang bisa dihantarkan ke seluruh tubuh ikut berkurang. Sehingga penderita CKD tidak bisa bernafas secara normal dan mengalami sesak nafas. Teknik ballon blowing dilakukan untuk mengurangi keluhan sesak napas yang di tandai dengan frekuensi napas membaik dan saturasi oksigen membaik. Tujuan penelitian ini adalah untuk mengetahui asuhan keperawatan pola nafas tidak efektif dengan balloon blowing pada pasien Chronic Kidney Disease. Penelitian ini menggunakan metode studi kasus. Teknik pengumpulan data dilakukan dengan wawancara (hasil wawancara berisi tentang identitas klien, keluhan utama, riwayat penyakit sekarang dan dahulu), observasi serta pemeriksaan fisik. Penelitian ini dilaksanakan di RSUD Kardinah Tegal selama 3  hari. Analisis data dalam studi kasus ini dilakukan secara deskriptif dan  data disajikan dalam bentuk narasi yang meliputi pengkajian, diagnosa, intervensi, implementasi sampai evaluasi. Hasil studi kasus pasien Chronic Kidney Disease dengan pola napas tidak efektif mengalami perubahan dihari ketiga setelah diberikan terapi balloon blowing, dimana terjadinya frekuensi pernapasan yang menurun dalam responden yakni di hari ke dua menjadi 24x/menit dan hari ketiga menjadi 20x/menit sehingga masalah teratasi dan intervensi dihentikan. Berdasarkan hasil evaluasi masalah pola napas tidak efektif dapat teratasi dengan terapi balloon blowing.
Hubungan Derajat Merokok (Indeks Brinkman) dengan Deteksi Dini Penyakit Paru Obstruktif Kronis (PUMA)”
Authors: Khasanah Sallma Kurnia , Hendra Basuki Samudra Prihatin , Setiyabudi Ragil
Published: October 2023

PPOK adalah pencetus terjadinya kematian ketiga  di dunia. Merokok adalah penyebab utama hingga 3,23 juta kematian tahun 2019. Di Indonesia angka PPOK menjangkau 9,2 juta orang kisaran 3,7%. Jateng PPOK mencapai 3,4%. Kabupaten Purbalinga tahun 2017 penderita PPOK terdiagnosis oleh Puskesmas dan jaringannya sebanyak 156 orang. Tujuan dari penelitian ini untuk mengidentifikasi karakteristik responden, derajat merokok, deteksi dini PPOK dan untuk mengetahui hubungan derajat merokok dengan deteksi dini PPOK. Metode menggunakan desain penelitian observasional analitic dengan penedekatan cross sectional. Responden pada penelitian ini berjumlah 60 responden diambil dengan teknik pengambilan sampel Total Sampling. Instrumen penelitian memakai kuisoner PUMA. Analisa data uji statistik bivariat menggunakan uji nonparametrik correlations spearmans. Hasil menunjukkan karakteristik responden semua berjenis kelamin laki-laki, usia minimum 40 tahun dan maksimum 81 tahun, pendidikan terbanyak SMA, jenis pekerjaan terbanyak wiraswasta, derajat merokok terbanyak kategori sedang, deteksi dini PPOK mayoritas beresiko ringan. Hasil uji bivariat menunjukkan nilai signifikansi 0,000 dengan α <0,05 sehingga (H0) ditolak dan (HI) diterima. Besar koofisien determinasi uji tersebut sebesar 68.9% artinya terdapat hubungan antara derajat merokok dengan deteksi dini PPOK.
Profil Hemodinamik Pasien Sectio Caesarea yang Mengalami Kejadian Hipotensi Intra Anestesi Spinal
Authors: Pontoh Nanda Aisyia , Setyawati Martyarini Budi , Adriyani Fauziah Hanum Nur
Published: October 2023

Anestesi spinal adalah teknik anestesi yang sering digunakan pada operasi sectio caesarea dibandingkan dengan anestesi lainnya. Meskipun demikian, penggunaan anestesi spinal mempunyai efek samping berupa hipotensi.  Tujuan penelitian ini adalah untuk mengetahui gambaran profil hemodinamik pasien sectio caesarea yang mengalami kejadian hipotensi intra anestesi spinal di Rumah Sakit Umum Daerah Dr. Soedirman Kebumen. Penelitian ini merupakan jenis studi kuantitatif yang menerapkan metode deskriptif. Penelitian ini juga menggunakan pendekatan cross-sectional dalam desain penelitiannya. Penelitian ini melibatkan 46 responden yang dipilih sebagai sampel dengan menggunakan metode purposive sampling. Uji univariat dipakai untuk analisis data. Pengumpulan data menggunakan bedside monitor dan lembar observasi untuk mencatat hasil monitoring hemodinamiknya. Hasil Penelitian didapatkan bahwa usia terbanyak pada responden yaitu usia 31,15 tahun, Indeks Masa tubuh yang paling dominan yaitu obesitas IMT ≥ 27 sebanyak 17 responden (37.0%). Kejadian hipotensi terhadap pasien sectio caesarea intra anestesi spinal yang paling dominan mengalami hipotensi terdapat pada menit ke-10 sebanyak 37 responden dengan presentase (80.4%), terdapat 29 orang mengalami hipotensi ringan dengan presentase (63.0%). Hemodinamik pasien sectio caesarea yang mengalami kejadian hipotensi intra anestesi spinal terdapat perubahan hemodinamik antara pre anestesi dan intra anestesi pada menit ke-5, 10, dan 15 dimana perubahan TDS yaitu sebesar 7.54 mmHg. TDD sebesar 6.11 mmHg. MAP sebesar 6.54 mmHg. HR sebesar 5.27 x/menit. RR sebesar -0.07 x/menit. Dan SpO2 sebesar 0.09 %.
Pengaruh Pemberian Terapi Guided Imagery terhadap Kecemasan pada Pasien Pre Operasi Sectio Caesarea
Authors: Sari Niken Liyana Octa , Yudono Danang Tri , Novitasari Dwi
Published: October 2023

Gangguan psikologis yang ditemui sebelum menjalani operasi caesarea meliputi timbulnya rasa ketakutan dan kecemasan. Jika tidak diatasi, situasi tersebut dapat menghambat proses persalinan. opsi untuk mengurangi kecemasan adalah melalui terapi imajinasi terbimbing, yang melibatkan teknik relaksasi untuk menciptakan perasaan kenyamanan dan merangsang pelepasan endorfin sehingga dapat mengurangi tingkat kecemasan. Tujuan dari penelitian ini mengidentifikasi dampak dari pemberian terapi imajinasi terbimbing dalam meminimalisir tingkat kecemasan terhadap pasien sebelum menjalani operasi caesarea. Dalam penelitian ini, digunakan metode kuantitatif dengan mengadopsi pendekatan desain pre-eksperimental satu kelompok pretest-posttest. Populasi penelitian ini yaitu pasien sebelum menjalani operasi caesarea, jumlah sampel sebanyak 57 individu yang terpilih melalui teknik purposive sampling. Tingkat kecemasan diukur melalui penggunaan lembar observasi Hamilton Anxiety Rating Scale (HARS), dan sesi terapi imajinasi terbimbing diberikan dua kali, masing-masing dengan durasi 15-20 menit. Pengolahan data dilakukan melalui penggunaan uji Wilcoxon Signed Ranks. Hasil menunjukan jika nilai dari Asymp. Sig. (2-tailed) yaitu sebesar 0,000 < 0,05 maka Ho ditolak serta Ha diterima serta nilai mean rank pretest-posttest 29.00 Ini mengindikasikan bahwa terdapat perbedaan antara nilai pretest dan posttest, Selain itu, terapi guided imagery berpengaruh terhadap tingkat kecemasan pasien sebelum menjalani operasi caesarea dan penurunan kecemasan yang signifikan. Kesimpulannya bahwa terapi imajinasi terbimbing mampu mengurangi tingkat kecemasan terhadap pasien sebelum menjalani operasi caesarea.
Analisis Pemberian Makanan Tambahan (MP-ASI) pada Anak Tinggi Badan Pendek
Authors: Sary Lolita , Sari Fitri Eka , Hermawan Dessy , Aryastuti Nurul , Rahayu Henni Puji Lestari
Published: October 2023

Pemberian makanan tambahan (MP-ASI) merupakan faktor yang berperan dalam kejadian stunting. Tujuan penelitian ini adalah diketahui hubungan pemberian makanan tambahan (MP-ASI) dengan kejadian tinggi badan pendek. Jenis penelitian kuantitatif pendekatan cross-sectional. Penelitian ini dilaksanakan di wilayah kerja Puskesmas Gading Rejo Kabupaten Pringsewu bulan Agustus-September 2023. Populasi adalah seluruh ibu yang mempunyai balita usia 6-24 bulan dengan jumlah 691 orang dan sampel sebanyak 146 orang dengan teknik simple random sampling. Uji statistik yang digunakan Chi-Square dan regresi logistik ganda. Hasil  analisis didapatkan tinggi badan anak sebagian besar normal sebanyak 80,8%, pemberian MP-ASI yang tepat sebanyak 78,1%, pemberian MP-ASI yang adekuat sebanyak 74,7%, pemberian MP-ASI yang aman sebanyak 77,4%, responsive feeding yang baik sebanyak 74,0%. Terdapat hubungan  antara ketepatan pemberian MP-ASI (p=0,000; OR=39,6), pemberian MP-ASI yang adekuat (p=0,000; OR=34,1), keamanan pemberian MP-ASI (p=0,000; OR=35,6), responsive feeding (p=0,000; OR=23,3), faktor yang paling berhubungan dengan tinggi badan pendek di Wilayah Kerja Puskesmas Gadingrejo Kabupaten Pringsewu Tahun 2023 adalah pemberian MP-ASI yang adekuat (OR=8,2).
Penatalaksanaan Holistik pada Pasien Pria Wanita 40 Tahun dengan Herpes Zoster dengan Pendekatan Kedokteran Keluarga
Authors: Muhammad Emir Yusuf , Gilang Muhammad , Saftarina Fitria
Published: October 2023

Herpes zoster dikenal juga sebagai cacar ular (shingles). Herpes zoster adalah suatu penyakit neurokutaneus yang disebabkan oleh reaktivasi atau aktivasi varicella zoster virus. Karakteristik herpes zoster berupa vesikel berkelompok dengan dasar kemerahan yang terasa nyeri pada daerah persarafan ganglion yang bersifat unilateral dan dermatomal. Herpes zoster merupakan penyakit yang dapat rekuren sewaktu-waktu, sehingga pasien yang menderita herpes perlu diberikan tatalaksana secara holistik. Tujuan penelitian ini adalah menerapkan pelayanan dokter keluarga berbasis evidence based medicine pada pasien dengan mengidentifikasi faktor risiko, masalah klinis, serta penatalaksanaan pasien berdasarkan kerangka penyelesaian masalah pasien dengan pendekatan patient centred dan family approach. Studi ini adalah laporan kasus. Data primer diperoleh melalui anamnesis, pemeriksaan fisik, kunjungan rumah untuk melengkapi data keluarga dan psikososial, serta lingkungan. Penilaian berdasarkan diagnosis holistik dari awal, proses dan akhir studi secara kuantitatif dan kualitatif. Responden yang digunakan berdasarkan beberapa faktor, yaitu jenis kelamin, usia, pendidikan, dan pekerjaan. Pasien seorang wanita usia 40 tahun dengan herpes zoster. Faktor internal pada kasus ialah riwayat menderita varisela saat remaja. Faktor eksternal meliputi kurangnya pengetahuan pasien dan keluarga terhadap penyakit herpes zoster yang diderita serta kurangnya menjaga kebersihan diri dan lingkungan. Dilakukan intervensi farmakologis berupa asiklovir tablet, salep asiklovir, paracetamol, dan cetirizine dan non farmakologis berupa edukasi untuk mencegah rekurensi. Penegakan diagnosis dan penatalaksanaan pada pasien ini telah dilakukan secara holistik, patient centered, family approach dan berdasarkan beberapa teori dan penelitian terkini. Pada proses perubahan perilaku, pasien dan keluarga sudah mencapai tahap adoption.
Comparison of Methods for Calculating Indirect Upstream Carbon Emissions from Information and Communication Technology Manufacturing
Authors: Jha Abhishek Kumar Rajesh , Andrae Anders S. G. , Mainali Brijesh
Published: October 2023

The use of Information Communication technology (ICT) is rapidly increasing in an age of digitalization. Measurement of carbon dioxide equivalent (CO2e) emissions from ICT is crucial for reducing them. Most ICT organizations focus on Scope 1 and 2 emissions as they have greater control over them, commonly ignoring Scope 3 emissions. Scope 3 Category 1 (S3C1) emissions occur throughout the raw material acquisition and manufacturing stages of an ICT product's life cycle accounting for a large portion of the sector's overall CO2e emissions and energy consumption. By not reporting Scope 3 emissions, companies lose the ability to reduce their overall CO2e corporate emissions. Although Category 1 and 11 under Scope 3 account for 85% of ICT's worldwide CO2e emissions, the methodologies for calculating S3C1 emissions in ICT are understudied. This study focuses on these emissions in the framework of Sustainable Development Goals 9, 12, and 13. Product life cycle assessment (PLCA) and Spend-based methods have been used to analyze S3C1 emissions in the ICT sector with two case examples of laptop computers and smartphones. The Excel Management Life Cycle Assessment (EMLCA) tool has been used for the S3C1 emissions estimation. PLCA and Spend-based methods are compared on their ability to calculate CO2e emissions. It is concluded that the Spend-based is faster than PLCA for predicting ICT emissions with modest uncertainty for smartphone and laptop components. Furthermore, this work explores the advantages and downsides of both methods.
Quick Response Code As A Game-Changer of Indonesian Digital Transactions
Authors: Sofwatunnisa Anggun Arikatus , Kartawinata Budi Rustandi , Akbar Aldi , Pradana Mahir
Published: October 2023

The purpose of this study is to elaborate on the Quick Response Code Indonesia Standard (QRIS) and its significant impact on digital transactions in Indonesia are covered in this publication. The QRIS standard for QR codes is a cutting-edge and effective electronic payment solution. The purpose of this study is to assess QRIS adoption and its effects on digital transactions in Indonesia. We use a systematic review and bibliometric analysis to discuss QRIS in this work. We draw some significant conclusions about this topic's writers and literature from our investigation.
On Transmission of COVID-19 in Terms of Semigraph
Authors: Bhattarai Kamal , Rohman Abdur , Nath Surajit Kr.
Published: October 2023

Semigraph Theory plays a significant role in most of the areas of science and technology. Every situation can be understandably articulated in terms of suitable graphs by using various approaches of Semigraph theory. Considering the recent advent of the pandemic in the world and the precautions taken for prevention of the COVID-19, it is the most appropriate way to utilize the Semigraph models with practical as well as theoretical aspects to prevent this epidemic. This work defines the two types of variable sets depending on the time factor. In this project, the mechanism of infection of the virus has been described in a simple way. The prevention method of the virus infection includes the partition of the semigraph i.e. isolating from other non-infected persons. The whole world is using the same method while controlling the infection of viruses.
Deep Learning based Brain Stroke Detection using Improved VGGNet
Authors: Arthi R Srisabarimani K.
Published: October 2023

Brain stroke is one of the critical health issues as the after effects provides physical inability and sometimes death. The inability of focus in the brain due to bleeding or clogged blood vessels leads to stroke. Early treatment and diagnosis are crucial in and following manual procedures takes more time which further increases the criticalness. Artificial intelligence and machine learning techniques hands together in medical domain and numerous applications are developed to reduce the diagnosis time and to improve the accuracy. Incorporating machine learning techniques in brain stroke detection is a familiar research arena and numerous research works are evolved with better solutions. However, the drive towards developing better system for brain stroke detection is still in progress. Thus, in this research work, deep learning-based brain stroke detection system is presented using improved VGGNet. Simulation analysis using a set of brain stroke data and the performance of learning algorithms are measured in terms of accuracy, sensitivity, specificity, precision, f-measure, and Jaccard index. The better performance of proposed model is comparatively analyzed with traditional machine learning algorithms like support vector machine, Naïve Bayes, Decision tree, K-Nearest neighbor, and recent deep learning models like ResNet, Squeeze Net, Alex Net, and Google Net algorithms. Experimental results validates that the Improved VGG model attained better performance for all the parameters. Specifically with 96.86% of detection accuracy improved VGG model detects the brain strokes effectively compared to other learning algorithms.
The Use of Technical Tools for the Protection of Copyright and Related Rights on the Internet
Authors:   Russian State University of Justice, Moscow, Russia, Kunin Evgeny I.
Published: October 2023

Problem statement. The specifics of the illegal distribution of copyright and related rights, namely the number of violations and the speed of their distribution, makes it impossible to identify and eliminate violations in an automated mode. The goals and objectives. To analyze the existing technical means that should be used to protect copyright and related rights on the Internet; to form an original classification of technical means in terms of their functional features; to develop a functional scheme of the protocol of actions of the copyright holder to stop the violation of copyright and/or related rights and to identify steps that can be automated using technical means. Results. Based on the analysis of statistical information on the number of network users, registered domain names and detected pirate sites, it was concluded that it is impossible to manually search and respond to violations of copyright and/or related rights.
On Responsibility for the Dissemination of Knowingly False Information and Discrediting the Use of the Armed Forces: A Comparative Analysis
Authors:   Russian State University of Justice, Moscow, Russia, Brilliantov Aleksandr V.
Published: October 2023

The article is devoted to the analysis of the elements of crimes “Public dissemination of knowingly false information about the use of the Armed Forces of the Russian Federation, the performance of their powers by state bodies of the Russian Federation” (Article 207.3 of the Criminal Code of the Russian Federation) and “Public actions aimed at discrediting the use of the Armed Forces of the Russian Federation in order to protect the interests of the Russian Federation and its citizens, maintain international peace and security or execution by state the bodies of the Russian Federation of their powers for these purposes” (art. 280.3 of the Criminal Code of the Russian Federation). The objects of crimes, elements of objective and subjective sides are compared, an attempt is made to distinguish between these elements. On the basis of the analysis, the problems associated with the practical application of the norms on the offenses in question are shown, and it is concluded that it is necessary to make adjustments to the criminal and administrative legislation. Judicial practice, materials of decisions of the Plenum of the Supreme Court of the Russian Federation are widely used.
Foreword: The Epstein Distinguished Speakers Collection
Authors: Montandon Seth A.
Published: October 2023

Foreword
ANTECEDENTS OF DIGITAL FINANCING ON MSME IN BANK SYARIAH INDONESIA (BEFORE AND AFTER MERGER)
Authors: Kusumaningsih Ani , Sudiyatmoko Agus
Published: October 2023

The aim of this research is to analyze the antecedents (factors which influence) of digital financing at Bank Syariah Indonesia (BSI). This study is focus on data before and after merger. The population of this study is employees of BRI (Bank Rakyat Indonesia) Syariah (before merger) and BSI (after merger) This study have eight objectives to analyze the effect of antecedents (accountability, adequacy of funds, accounting information, operational risk, internal control, and credit analysis) on digital financing for MSME at BSI. The sample was determined based on the random sampling method, in which 100 respondents were obtained using the Slovin formula. All respondents were asked to fill out the questionnaire that had been prepared based on indicators of variables. Data analysis was performed using Partial Least Square-Structural Equation Modeling (PLS-SEM). The research results indicate that from eight hypothesis, six of them are affect and two of them are not affect before merger, but after merger the results show that five of them are affect and three of them are not affect.
PENGARUH PEMBERIAN KOMPENSASI DAN MOTIVASI TERHADAP KINERJA KARYAWAN GUNUNG AGUNG SENAYAN CITY MALL JAKARTA PUSAT
Authors: Kustini Endang , Prasetiyani Desi , Guruh Muhamad
Published: October 2023

This research aims to determine the effect of compensation (X1) and motivation (X2) together on employee performance (Y), the effect of motivation (X2) on (Y) employee performance and the effect of compensation (X1) on employee performance (Y). The type of research carried out was a quantitative research method by distributing and collecting questionnaires about employee compensation, motivation and performance to 58 respondents. The analysis technique carried out is using Validity Test, Reliability Test, Classical Assumption Test, Regression Analysis, Correlation Coefficient Analysis, Determination Coefficient Analysis and Hypothesis Testing. The research results show that providing compensation has a positive and significant effect on employee performance at Gunung Agung Senayan City Mall. This is proven by the value obtained for the regression equation Y = 8.463 + 0.668X1. Hypothesis test results were also obtained for the Compensation variable (X1) on Employee Performance (Y) of 0.000 < 0.05 or a calculated t value of 5.736 > t table 2.003. Motivation has a positive and significant effect on employee performance at Gunung Agung Senayan City Mall). This is proven by the value obtained for the regression equation Y = 9.822 + 0.610X2. Hypothesis test results were also obtained for the Motivation variable (X2) on Employee Performance (Y) of 0.000 < 0.05 or a calculated t value of 5.063 > t table 2.003. And providing compensation and motivation together have a positive and significant effect on employee performance at Gunung Agung Senayan City Mall. This is proven by the value obtained for the regression equation Y = 3.500 + 0.489X1 + 0.389X2, for the influence of the compensation variable (X1) and the motivation variable (X2) on the employee performance variable (Y) is 0.000 < 0.05.
PENGARUH KETAHANMALANGAN DAN KOMUNIKASI INTERPERSONAL TERHADAP ETOS KERJA GURU SEKOLAH DASAR SWASTA DI KECAMATAN CILANDAK JAKARTA SELATAN
Authors: Putren Irenne
Published: October 2023

Research conducted has proven that there is an influence of Adversity Quotient and interpersonal communication on the work ethic of private elementary school teachers in Cilandak sub-district, South Jakarta. The research used is research with survey methods and data collection with questionnaires. It can be seen from the result that there is a positive direct effect on each variable. Research shows that the level of resilience to adversity has a positive influence on the work ethic of private elementary school teachers in Cilandak District, South Jakarta. This means that teachers who have a higher level of resilience tend to have a stronger work ethic. The research results also show that interpersonal communication has an important role in influencing teacher work ethic. Teachers who are able to communicate effectively with fellow teachers, students and other related parties tend to have a better work ethic.
LITERATURE REVIEW: PERAN CAREER DEVELOPMENT DALAM MENINGKATKAN WORK ENGAGEMENT DOSEN
Authors: Muchtadin Muchtadin , Zainal Veithzal Rivai , Riyanto Setyo , Nurhayati Mafizatun
Published: October 2023

Work engagement is one of the crucial aspects that a lecturer must possess. This research aims to provide an overview of the relationship between career development and work engagement among employees, including lecturers. The references for this study were obtained from Google Scholar, with specific criteria spanning from 2014 to 2023, focusing on work engagement dimensions of vigor, dedication, and absorption. The research findings indicate variations in the connection between career development and work engagement. These differences are believed to be attributed to organizational support and length of service factors. Over the past decade, no significant association has been found between career development and work engagement among lecturers in Indonesia.
PENGARUH DISIPLIN KERJA DAN PROMOSI JABATAN TERHADAP KINERJA KARYAWAN PADA HYPERMART PEJATEN VILLAGE PASAR MINGGU DI JAKARTA SELATAN
Authors: Hermawati Rahmi , Sopandi Andi , Sari Ratna
Published: October 2023

This research aims to determine the influence of work discipline and job promotion on employee performance, both partially and simultaneously. The research method used is quantitative, and the nature of the research is associative, with linear regression analysis. Based on the test results, it was found that work discipline has a positive and significant influence on employee performance, with a calculated t-value of 5.613 > tabled t-value of 1.983 and a significance value (sig) of 0.000 < 0.05. This indicates that the better the work discipline of employees in the company, the higher their performance. Job promotion also has a positive and significant influence on employee performance, with a calculated t-value of 4.672 > tabled t-value of 1.983 and a significance value (sig) of 0.000 < 0.05. This shows that the more frequent a company provides job promotions to employees, the higher their performance will be. Both work discipline and job promotion have a positive and significant influence on employee performance, with a calculated F-value of 53.952 > tabled F-value of 3.09 and a significance value (Sig) of 0.000 < 0.05. This indicates that if work discipline and job promotion can be improved and enhanced, employee performance will increase. The adjusted coefficient of determination (Adjusted R Square) is 0.505, indicating that the variables of work discipline and job promotion contribute 50.5% to employee performance, while the remaining 49.5% is influenced by other factors outside the scope of this study.