bluuebunny/crossref_metadata_2025 huggingface dataset:
Information and Communication Technology for Managing Social Isolation and Loneliness Among People Living With Parkinson Disease: Qualitative Study of Barriers and Facilitators (Preprint)
Authors: Thangavel Gomathi , Memedi Mevludin , Hedström Karin
Published: April 2023

BACKGROUND

Parkinson disease (PD) is a complex, noncurable, and progressive neurological disease affecting different areas of the human nervous system. PD is associated with both motor and nonmotor symptoms, which negatively affect patients’ quality of life and may cause changes in socialization such as intentional social withdrawal. This may further lead to social isolation and loneliness. The use of information and communication technology (ICT) plays an important role in managing social isolation and loneliness. Currently, there is a lack of research focusing on designing and developing ICT solutions that specifically address social isolation and loneliness among people living with PD.

OBJECTIVE

This study addresses this gap by investigating barriers and social needs in the context of social isolation, loneliness, and technology use among people living with PD. The insights gained can inform the development of effective ICT solutions, which can address social isolation and loneliness and improve the quality of life for people living with PD.

METHODS

A qualitative study with 2 phases of data collection were conducted. During the first phase, 9 health care professionals and 16 people living with PD were interviewed to understand how PD affects social life and technology use. During the second phase, 2 focus groups were conducted with 4 people living with PD in each group to gather insights into their needs and identify ways to manage social isolation and loneliness. Thematic analysis was used to analyze both data sets and identify key themes.

RESULTS

The results showed that the barriers experienced by people living with PD due to PD such as “fatigue,” “psychological conditions,” “social stigma,” and “medication side effects” affect their social life. People living with PD also experience difficulties using a keyboard and mouse, remembering passwords, and navigating complex applications due to their PD-related physical and cognitive limitations. To manage their social isolation and loneliness, people living with PD suggested having a simple and easy-to-use solution, allowing them to participate in a digital community based on their interests, communicate with others, and receive recommendations for social events.

CONCLUSIONS

The new ICT solutions focusing on social isolation and loneliness among people living with PD should consider the barriers restricting user’s social activities and technology use. Given the wide range of needs and barriers experienced by people living with PD, it is more suitable to adopt user-centered design approaches that emphasize the active participation of end users in the design process. Importantly, any ICT solution designed for people living with PD should not encourage internet addiction, which will further contribute to the person’s withdrawal from society.
Potensi Tanaman Rambutan (Nephelium lappaceum L.) sebagai Antibakteri
Authors: Bina Yohana Maria , Utomo Yoanes Fransiskus Regis Widyo , Prjanaparamita Anandha Nabila , Mahadhika Jullius Ivan , Mawarni Maria Theresia , Setyaningsih Dewi , Riswanto Florentinus Dika Octa
Published: April 2023

Tingginya curah hujan dan rendahnya sanitasi dapat mengakibatkan munculnya berbagai infeksi oleh bakteri. Untuk mengatasi hal tersebut, agen antibakteri yang sesuai dapat digunakan. Resistensi antibiotik merupakan masalah global yang mendesak menyebabkan berkurangnya efektivitas antibiotik dalam mengatasi infeksi bakteri. Permasalahan ini perlu diatasi dengan pencarian alternatif senyawa dengan aktivitas antimikroba, termasuk yang berasal dari bahan alam. Rambutan (Nephelium lappaceum L.) merupakan tanaman yang berasal dari Indonesia dan Malaysia, serta tersebar di Asia Tenggara. Tanaman rambutan telah terbukti memiliki khasiat dalam pengobatan, seperti antelmintik dan antidiare. Beberapa penelitian ilmiah telah menunjukkan bahwa daun, biji, dan kulit buah rambutan memiliki aktivitas antibakteri. Aktivitas tersebut ditunjukkan oleh ekstrak atau fraksi yang diperoleh melalui berbagai metode dan pelarut yang berbeda. Aktivitas antibakteri ini dapat timbul karena adanya kandungan berbagai senyawa, termasuk senyawa-senyawa fenolik, seperti geraniin, ellagic acid, kuersetin, dan corilagin. Beberapa penelitian telah menunjukkan adanya aktivitas antibakteri dari tanaman rambutan terhadap bakteri yang resisten. Artikel review ini disusun menggunakan metode studi pustaka melalui penelusuran artikel penelitian, artikel ilmiah, dan review jurnal pada database elektronik seperti internet, Google Scholar, Pubmed, ScienceDirect, dan Elsevier. Artikel review ini bertujuan untuk membahas dan memberikan informasi hasil penelitian terbaru terkait aktivitas antibakteri tanaman rambutan yang diharapkan dapat menjadi informasi acuan para peneliti di masa mendatang untuk mengambangkan riset yang terkait.
Activity and Selectivity of Mesoporous Silica Catalyst for Hydrocracking Process of Used Palm Oil into Biogasoline
Authors: Suseno Ahmad , Wijaya Karna , Heraldy Edy , Hakim Lukman , Saputri Wahyu Dita , Gunawan Gunawan
Published: April 2023

Research on the synthesis of mesoporous silica catalyst, as well as its activity and selectivity in the hydrocracking of used palm oil, has been carried out. The research involved the preparation of mesoporous silica catalyst by varying the volume ratio of TEOS:CTAB at 2:1, 4:1, and 8:1, then calcined at 500 °C. Synthesis success was confirmed by FTIR, XRD, SEM-EDX, GSA, and hydrocracking selectivity by GC-MS analysis. The results showed that the more TEOS added, the silica bond composition, crystallinity, pore size, and product selectivity increased. The best catalyst performance was obtained from a TEOS:CTAB ratio of 8:1 at a calcination temperature of 500 °C (MCT81-500), which indicated the presence of Si-OH and Si-O-Si groups with a Si percentage of 45.31%, pore size diameter of 31.912 nm, and a total pore volume of 0.040 cc/g. In addition, the application of MCT81-500 in the hydrocracking process of used palm oil can produce a bio-gasoline (C5-C12) and kerosene (C12-C15) of 92.24 and 7.76 wt.%, respectively. This study shows that mesoporous silica has good potential for catalytic activity to convert used cooking oil waste into an environmentally friendly energy source.
New Heterocyclic Organo-Chalcogenide Compounds: Synthesis, Physicochemical Characterization, and Evaluation of Anticancer Activity against Breast Cancer Cells
Authors: Abbas Hayat Hamza , Al-Luaibi Majeed Yacoob , Al-Assadi Mohammed Jassem
Published: April 2023

This work aimed to synthesize, characterize and evaluate the thermal stability of new sulfur and selenium organochalcogenide derivatives and to test the cytotoxic activity against breast adenocarcinoma cell line (MCF-7) through conducting MTT assay and AO/EB dual staining-technique. Two series of ten organo-chalcogen compounds: 4-(substituted)phenylthiomorpholine-3,5-dione and 4-(substituted)phenylselenomorpholine-3,5-dione were prepared by the reaction of Na2S·3H2O and NaHSe with N-(substituted)phenyl-2-chloro-N-(2-chloroacetyl)acetamide, respectively, under nitrogen atmosphere to give the corresponding cyclic chalcogenide ligands. All new compounds were characterized by melting point, FTIR, elemental analysis, UV-Visible, 1H-NMR and 13C-NMR. Meanwhile, TG/DTA analysis of some of these ligands was conducted to evaluate the thermal stability, kinetic, and characteristic thermodynamic parameters. Absorption spectroscopy was used to investigate these compounds with human DNA. The experimental results investigated a hypochromic effect via intercalation binding mode. The role of the prepared ligands in breast cell lines has been investigated by conducting MTT assay via spectroscopic techniques on HBL100 and MCF-7, normal and cancer breast cell lines, respectively. Cell death was seen after AO/EB dye staining method employing the fluorescence microscopy technique. The results revealed that these compounds possess cytotoxic activity on the MCF-7 and HBL-100 cell lines at a fixed concentration.
Synthesis and Biological Activity Study of Co and Cr Complexes with α-(2-Salsayl)-N-phenyl Nitrone and Oxide Nanoparticles
Authors: Issa Dhamiaa Abdul-Shaheed , Abdullah Hayder Baqer , Al-Mashal Faeza Abdulkareem
Published: April 2023

This paper describes the synthesis of two complexes from the ligand α-(2-Salsayl)-N-phenyl nitrone with CoCl2 and CrCl2. The ligand was characterized by several spectroscopic techniques (ultraviolet/visible (UV/Vis), nuclear magnetic resonance (1H-NMR and 13C-NMR), Fourier-transform infrared spectroscopy (FTIR), and mass spectrometry (MS). While infrared, ultraviolet-visible (UV-Vis), thermal analysis, and job method studies were used to reveal the structure of the complexes. The synthesized complexes were then synthesized by the sonochemical method, and the copper and chromium oxide nanoparticles were produced using the thermal decomposition method. Scanning electron microscopy (SEM), Energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) characterization confirmed the formation of Co3O4 and Cr2O3 nanoparticles. Antimicrobial studies of the complexes against some microorganisms, such as Staphylococcus epidermis and Escherichia coli, utilizing the disk diffusion method, revealed the antibacterial activity of the complexes.
Fast Microwave-Assisted Green Synthesis of Silver Nanoparticles Using Low Concentration of Seminyak (Champeria sp.) Leaf Extract
Authors: Ananda Muhammad Bagas , Sanjaya Fathan Aditya , Bachrurozy Tami , Ar Rasyid Helmi Majid , Barlian Anggraini , Aimon Akfiny Hasdi , Qulub Fitriyatul , Widiyanti Prihartini , Wibowo Arie
Published: April 2023

Silver nanoparticles (AgNPs) are fascinating materials for biomedical applications thanks to their strong antibacterial activity and biocompatibility. This study applied the green synthesis method using 0.5 wt.% Seminyak leaf extract and assisted with one min microwave irradiation to enhance AgNPs formation. Extremely small sizes AgNPs with an average particle size of 9.1 ± 4.1 nm and spherical shapes were obtained. The synthesized AgNPs displayed potent antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria with a zone of inhibition of 12.3 ± 0.1 and 13.7 ± 0.7 mm, respectively. The MTT assay results demonstrated that the cells’ viability of the obtained AgNPs was 88.5 ± 7.0 %, implying biocompatibility for biomedical applications.
Oxygen Reduction Reaction (ORR) of Pt/C Standard in Different Electrolyte Solutions and Terbium(III) Monoporphyrinato Complex
Authors: Wibowo Atmanto Heru , Wati Annisa Nur Buana , Santria Anas , Masykur Abu , Firdaus Maulidan
Published: April 2023

Electrocatalytic parameters of a Pt/C standard and a sample of terbium(III) monoporphyrinato were investigated in different solutions. N electron transfer, Tafel slope, Eonset, and overpotential of the catalyst of Pt/C in different solutions were calculated and analyzed using a rotating ring disk electrode (RRDE) in 0.5 M H2SO4, 0.1 M HClO4 and 0.1 M NaOH. In the RRDE measurements, a bipotentiostat at a potential range of 1.03 to 0.05 V vs RHE (Ering = 1.2 V vs RHE) with a scan rate of 5 mV/s and rotation rates of 200, 400, 900, 1600 and 2500 rpm was used. Hereafter, the test of terbium(III) monoporphyrinato compound formulated in [Tb(TPP)(cyclen)]Cl (TPP = 5,10,15,20-tetraphenylporphyrinato; cyclen = 1,4,7,10-tetraazacyclododecane) as a candidate material for ORR electrocatalyst was also done. The results showed that the measurement of Pt/C standards was satisfactory according to the literature for all parameters with the n electron transfer close to 4 in all electrolytes media. [Tb(TPP)(cyclen)]Cl had an n electron transfer value of 2.38, suggesting that the [Tb(TPP)(cyclen)]Cl compound has less potential for ORR catalysts.
Comparative Study of Soft Template on Gunningite Synthesis for Ibuprofen Adsorption Application
Authors: Ulfa Maria , Apriliani Windi
Published: April 2023

This study aimed to investigate the effect of soft template variations on Zinc Sulfate Hydrate (Gunningite) synthesis and the maximum adsorption capacity of ibuprofen. This study employed the soft template method and hydrothermal at 100 °C, followed by calcination at 550 °C. Here, ZnSO4 heptahydrate was used as the precursor for different templates. XRD analysis exhibited that the crystal sizes of Gunningite-F127G, Gunningite-F127, Gunningite-P123G, Gunningite-P123, and Gunningite-G were 18.35; 25.33; 25.67; 27.30; and 24.24 nm with crystallinity degrees of 36.89; 42.62; 46.83; 41.27; and 40.62%, respectively. FTIR examination indicated that the five samples contained functional groups of OH stretching at 3170 cm–1, Zn-O-Zn at 1637 cm–1, Zn-S=O symmetric and asymmetric at 900 and 1056 cm–1, and Zn-O at 521 cm–1. Furthermore, SEM-EDX investigation revealed that the morphology of all Gunningite samples was inhomogeneous due to agglomeration. Besides that, the elemental compositions in the samples were dominated by Zn and O elements. The maximum adsorption capacity obtained from each sample was 221.1 mg/g (Gunningite-F127G); 226.06 mg/g (Gunningite-F127); 234.23 mg/g (Gunningite-P123G); 229.76 mg/g (Gunningite-P123); and 222.85 mg/g (Gunningite-G). Moreover, the Gunningite kinetic model of ibuprofen adsorption followed Ho and McKay's pseudo-second-order kinetic model.
Effect of Activated Carbon Particle Size on Methylene Blue Adsorption Process in Textile Wastewater
Authors: Musthofa Akhmad Masykur Hadi , Syafila Mindriany , Helmy Qomarudin
Published: April 2023

Up to 60–70% of the total textile dyes produced are azo dyes. An example of azo dye is methylene blue, which is commonly used in dyeing wool, silk, and cotton. This substance possessed harmful effects on the environment. Therefore, the removal process is mandatory. The adsorption process is a common method for dye removal in wastewater. One innovation to increase adsorption efficiency even further is by reducing adsorbent particle size. To understand the effect of adsorbent particle size on the adsorption process, in this study, granular activated carbon (GAC) was pulverized into powder (PAC) and superfine powder (SPAC). Adsorbent characterizations, isotherm, kinetics, and thermodynamics tests were conducted. Based on this study, surface area, pore volume, and adsorption capacity were increased for smaller adsorbent particle sizes. Isotherm and kinetic analysis showed that there was no difference in the isotherm and kinetic models that applied to each activated carbon, but there was an increase in the isotherm and kinetic coefficient values at smaller particle sizes. Meanwhile, based on the thermodynamic test, there were differences in the dominant adsorption mechanism for each activated carbon. In GAC and SPAC, the dominant adsorption mechanism was electrostatic interactions, while in PAC was van der Waals forces.
SIMULAKRA PADA FOTO IKLAN BANK DANAMON KARYA ANDRY DILINDRA
Authors: Shofwan Teuku Ade Nur
Published: April 2023

Perkembangan teknologi fotografi terus memainkan perannya dalam merepresentasikan perubahan dan dapat berfungsi sebagai kendaraan komunikasi massa dan propaganda. Karakteristik dari medium seni dua dimensi ini juga dapat dipergunakan dalam berbagai hal, salah satunya pada dunia periklanan. Iklan merupakan representasi dari segudang pengalaman emosional yang pernah manusia alami, juga bentuk lain dari sebuah penggambaran harapan. Psikologi harapan dan emosional adalah senjata utama yang setiap hari menyerang masyarakat dari berbagai sisi kehidupan ekonomi kapitalistik. Akibatnya, iklan menjadi semacam katarsis di tengah himpitan kebutuhan yang terus meningkat. Baudrillard memandang sistem objek konsumen dan sistem komunikasi pada dasar periklanan, adalah sebagai pembentukan ‘sebuah kode signifikansi,’ yang mengontrol objek dan individu di tengah masyarakat. Kode tersebut dapat dianalisis melalui studi kasus pada seri iklan Bank Danamon yang merupakan karya fotografer iklan bernama Andry Dilindra. Pada iklan tersebut seolah-olah menawarkan kemudahan, namun pada sisi lain, juga merupakan gambaran kondisi pelipatan ruang-waktu yang dapat bermanifestasi menjadi pelipatan gaya hidup dalam kehidupan sosial. Pelipatan ruang-waktu yang ditunjukkan pada iklan ini menjadi sebuah ekstasi bagi manusia yang menjadikan dirinya dikuasai eskalasi dan berada dalam proses perputaran di luar kontrol yang kehilangan kebermaknaan dan esensi. Ia merupakan kode signifikansi yang mencengkram dunia sosial dan mencapai tahap fraktal dimana kondisi manusia tidak lagi dapat mendeteksi perbedaan antara yang nyata dan imajiner atau menciptakan dunia yang disebut Baudrillard sebagai ekstasis. Semuanya hanya hiperrealitas.
MUSIC INTERACTION AND MOVEMENT IN JAVANESE DANCE: CASE STUDY ON BEKSAN BEDHAYA GANDAKUSUMA MANGKUNEGARAN STYLE
Authors: Sriyadi Sriyadi
Published: April 2023

The music and movement patterns in Javanese dance occupy a significant position, which both of them have an integral relationship in forming the construction of a dance.  It represented through the relationship between dance music and the technique of composing and executing movement patterns. This article examines the integral relationship between dance music and movement patterns to determine the importance of these two components in the formation of Javanese dance . The case study chosen to show this integral relationship is the Mangkunegaran style of Bêdhåyå Gåndåkusumå dance. The bêdhåyå dance is the result of absorption carried out by K.G.P.A.A. Mangkunegara VII (1916-1944) through a learning system at Kridha Beksa Wirama Yogyakarta. This research uses an ethnochoreological approach in the form of qualitative research. The position of dance as a multidimensional object in the ethnochoreological approach is seen through the choreographic dimension, which is expected to be able to describe the integral relationship between dance music and movement patterns in forming a Javanese dance construction. Data collection techniques were carried out through participatory observation, literature study, and interviews. Based on research results in the Bêdhåyå Gåndåkusumå dance, the technique for composing movement patterns always pay attention to the instrument colotomy  of dance music. Gêndhing rhythms have contributed to realizing the aesthetic stability of the execution of a series of movements.
Inclement Weather and Risk of Missing Scheduled Hemodialysis Appointments among Patients with Kidney Failure
Authors: Remigio Richard V. , Song Hyeonjin , Raimann Jochen G. , Kotanko Peter , Maddux Frank W. , Lasky Rachel A. , He Xin , Sapkota Amir
Published: April 2023

Background

Nonadherence to hemodialysis appointments could potentially result in health complications that can influence morbidity and mortality. We examined the association between different types of inclement weather and hemodialysis appointment adherence.

Methods

We analyzed health records of 60,135 patients with kidney failure who received in-center hemodialysis treatment at Fresenius Kidney Care clinics across the Northeastern US counties during 2001–2019. County-level daily meteorological data on rainfall, hurricane and tropical storm events, snowfall, snow depth, and wind speed were extracted using National Oceanic and Atmosphere Agency data sources. A time-stratified case-crossover study design with conditional Poisson regression was used to estimate the effect of inclement weather exposures within the Northeastern US region. We applied a distributed lag nonlinear model framework to evaluate the delayed effect of inclement weather for up to 1 week.

Results

We observed positive associations between inclement weather and missed appointment (rainfall, hurricane and tropical storm, snowfall, snow depth, and wind advisory) when compared with noninclement weather days. The risk of missed appointments was most pronounced during the day of inclement weather (lag 0) for rainfall (incidence rate ratio [RR], 1.03 per 10-mm rainfall; 95% confidence interval [CI], 1.02 to 1.03) and snowfall (RR, 1.02; 95% CI, 1.01 to 1.02). Over 7 days (lag 0–6), hurricane and tropical storm exposures were associated with a 55% higher risk of missed appointments (RR, 1.55; 95% CI, 1.22 to 1.98). Similarly, 7-day cumulative exposure to sustained wind advisories was associated with 29% higher risk (RR, 1.29; 95% CI, 1.25 to 1.31), while wind gusts advisories showed a 34% higher risk (RR, 1.34; 95% CI, 1.29 to 1.39) of missed appointment.

Conclusions

Inclement weather was associated with higher risk of missed hemodialysis appointments within the Northeastern United States. Furthermore, the association between inclement weather and missed hemodialysis appointments persisted for several days, depending on the inclement weather type.
Kidney Stone Events after Kidney Transplant in the United States
Authors: Ganesan Calyani , Holmes Malorie , Liu Sai , Montez-Rath Maria , Conti Simon , Chang Timothy C. , Lenihan Colin R. , Cheng Xingxing S. , Chertow Glenn M. , Leppert John T. , Pao Alan C.
Published: April 2023

Background

Kidney stone disease is common and can lead to complications such as AKI, urinary tract obstruction, and urosepsis. In kidney transplant recipients, complications from kidney stone events can also lead to rejection and allograft failure. There is limited information on the incidence of kidney stone events in transplant recipients.

Methods

We identified 83,535 patients from the United States Renal Data System who received their first kidney transplant between January 1, 2007, and December 31, 2018. We examined the incidence of kidney stone events and identified risk factors associated with a kidney stone event in the first 3 years after transplantation.

Results

We found 1436 patients (1.7%) who were diagnosed with a kidney stone in the 3 years after kidney transplant. The unadjusted incidence rate for a kidney stone event was 7.8 per 1000 person-years. The median time from transplant to a kidney stone diagnosis was 0.61 (25%–75% range 0.19–1.46) years. Patients with a history of kidney stones were at greatest risk of a kidney stone event after transplant (hazard ratio [HR], 4.65; 95% confidence interval [CI], 3.82 to 5.65). Other notable risk factors included a diagnosis of gout (HR, 1.53; 95% CI, 1.31 to 1.80), hypertension (HR, 1.29; 95% CI, 1.00 to 1.66), and a dialysis of vintage of ≥9 years (HR, 1.48; 95% CI, 1.18 to 1.86; ref vintage ≤2.5 years).

Conclusions

Approximately 2% of kidney transplant recipients were diagnosed with a kidney stone in the 3 years after kidney transplant. Risk factors of a kidney stone event include a history of kidney stones and longer dialysis vintage.

Podcast

This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/CJASN/2023_06_08_CJN0000000000000176.mp3
Lo digital es político: universitarias frente a la violencia digital hacia las mujeres
Authors: Gómez Cruz Brenda Magali
Published: April 2023

El presente artículo tiene como objetivo analizar las experiencias de mujeres universitarias de la FES Zaragoza (UNAM) ante la violencia digital, los significados que le otorgan y la manera en que le hacen frente. A través de una etnografía digital y mediante un análisis narrativo con perspectiva de género feminista, se encontró que las universitarias en el espacio digital consideran que: 1) este tipo de violencia está normalizada socialmente, 2) hay más condiciones de vulnerabilidad para las mujeres que para los hombres y 3) es necesario implementar prácticas de cuidado personal y colectivo que les permitan sentirse más seguras en dicho espacio. Se concluye que «lo digital es político», en términos de que está atravesado por el poder, ante lo cual las universitarias se organizan para transformar su condición de género.
A Batch Based Approach for Tweeting Geotags of Social Media Attributes
Authors: Rajabushanam Dr. , K Francy. , G Rakshitha , Vaishnavi G. Y. K. , G Meghana Reddy.
Published: April 2023

Abstract: Online evaluation systems play an vital position in influencing client conduct and choice making, attracting many spammers to insert faux remarks to review content material and rankings. To increase advantages and improve user experience, some online evaluation systems permit customers to shape social relationships with every different and inspire their interaction. In this text, we purpose to provide an powerful and green method to pick out assessment spammers, incorporating social relationships primarily based on two assumptions, that human beings are much more likely to help opinions from the ones associated with them as straightforward and evaluate spammers are less probably to guide. Extremely good community relationships with everyday users. The contribution of this article is -fold: (1) we give an explanation for how social relationships may be covered in the estimation of estimation prediction and we suggest a version of accept as true with estimation prediction the usage of proximity as a accept as true with weight, and (2) we increase a trust-based estimation model. An instance The detection version is primarily based on a discrepancy assessment that iteratively calculates the overall reliability rating for a selected consumer as a spam sign. Experiments with a questionnaire accrued from Yelp.Com display that the consider-primarily based prediction technique offers better accuracy than the standard CF approach, and that there is a strong comparison among social attitudes and overall believe ratings.
Tackling the Fake News Epidemic using Machine Learning Algorithm
Authors: Singh Rahul Kumar , Bharati Rajesh
Published: April 2023

Abstract: Fake news has been a problem since the internet boom. Websites that keep us up to date with what's going on in the world are the perfect breeding ground for bad news and fake news. Fighting fake news is important because the world is knowledge-based. People do not make important decisions based on information; they also form their own ideas. Incorrect information can cause serious damage. It is not possible to identify all messages from a contact. This article attempts to speed up the fake news detection process by recommending a reliable fake news classification method. Machine learning contains different algorithms like naive Bayes, passive-aggressive classifiers and deep neural networks used eight different datasets from different sources. The text also includes the analysis and results of each model. With the right standards and the right tools, the task of detecting fake news will not be trivial.
Examining the Economic Impact of Cayenne Pepper in Traditional Markets of Makassar City: A Price Analysis Study
Authors: Diansari Pipi , Rukmana Didi , Wahyudi
Published: April 2023

The price fluctuation of cayenne pepper has significant impacts on traders' cost performance and income. Therefore, determining the economic price for selling cayenne pepper is crucial. Economic price refers to the fair price for the sale of a commodity or product. This research aims to determine the economic price of cayenne pepper at Kalimbu Market in Makassar City, using 20 traders as respondents and primary data analysis. Cost analysis and break-even point techniques were employed to determine the basic price of cayenne pepper, followed by a switching value analysis to assess the percentage change in costs that could be tolerated. The study findings reveal that the economic price for kiosk cayenne pepper traders is Rp. 57,664/Kg, while the other economic price for kiosk cayenne pepper traders is Rp. 58,068/Kg. These results imply that the selling price set by the cayenne pepper trader is IDR 60,000, resulting in a small profit that is insufficient to meet the personal and family needs of traders.
Sweetening the Deal: Investigating the Impact of Product Quality and Price on Honey Purchase Behavior at PT Kembang Joyo Sriwijaya, Malang
Authors: Nursahid Imron Dwi Nursahid , Mufriantie Fithri
Published: April 2023

Consumer purchasing decisions are complex individual processes that involve numerous considerations before making a purchase. Product quality and price are two significant factors that influence consumer purchasing decisions. Understanding the influence of these factors is crucial for businesses seeking to improve their sales and meet the expectations of their customers. This study aims to investigate the impact of product quality and price on consumer purchasing decisions for honey at PT Kembang Joyo Sriwijaya Malang. The study employed a quantitative research design, using accidental sampling to select consumers who had purchased honey from the store more than once. Data was collected from 75 respondents, and structural equation modeling (SEM-PLS) was used to analyze the data. The analysis involved examining the relationship between product quality and price with consumer purchasing decisions. The findings of the study showed that product quality and price had a significant positive effect on consumer purchasing decisions. Product quality had a positive relationship with purchasing decisions, influencing 20.6% of the variance (path coefficient=0.206, t-statistic=2.410, p-value=0.016). Price had a stronger positive relationship, influencing 65.4% of the variance (path coefficient=0.654, t-statistic=10.534, p-value=0.000). These results suggest that both product quality and price are essential factors to consider when seeking to improve sales and meet customer expectations in the honey market at PT Kembang Joyo Sriwijaya Malang.
MARS-PD: Meridian Activation Remedy System for Parkinson’s Disease
Authors: Park Miso S. , Kim Chan-young , Choi In-woo , Chae In-cheol , Hur Wangjung , Park SangSoo , Yoo Horyong
Published: April 2023

Objective: There are currently no disease-modifying medications or definite long-term sustainable interventions for patients with Parkinson’s disease (PD), indicating an unmet treatment need. Our goal was to create a long-term sustainable intervention for PD patients that can be used in Korean medicine clinics.Methods: The Meridian Activation Remedy System (MARS) was created to stimulate a patient’s 12 meridians and sinew channels using a combination of acupoint stimulation and exercise. The acupoints and motions used in MARS were selected through literature studies and expert advice. The methodologies were refined using observational and case studies. With slow and fast movements, the MARS intervention was intended to activate both slow- and fast-twitch muscle fibers. Intradermal acupuncture and motion that shift the center of gravity were employed to enhance the patient’s balance and proprioception. In addition, the intervention included alternating movement exercises to address the complex cognitive decline commonly occurring in PD patients.Results: The following acupoints were chosen for the MARS intervention: bilateral Hegu (LI4), Houxi (SI3), Waiguan (TE5), Neiguan (PC6), Zhongchong (PC9), Yuji (LU10), Zusanli (ST36), Yanglingquan (GB34), Taichong (LR3), Kunlun (BL60), and Taixi (KI3). We also developed actions that can stimulate the body’s 12 meridians.Conclusion: We developed the MARS intervention, which combines acupuncture and exercise, to address the unmet therapeutic needs of PD patients. We hope that with additional research, the MARS intervention can be set as an effective therapeutic program for PD patients.
Федеральный закон № 73-ФЗ и вопросы организации системы охраны объектов культурного наследия
Authors: Митягин Сергей , Шевченко Элеонора , Семенцов Сергей
Published: April 2023

Охрана объектов культурного наследия как явление и как процесс характеризует уровень цивилизацион­ного развития конкретной общественной формации в данном административно-государственном образовании. В структуре объектов культурного наследия, с точки зрения организации их охраны, наибольшую сложность занимают экстерьерные объекты материально-пространственной среды в виде функционирующих и руинированных комплексов. Охрана этих объ­ектов требует установления разного рода ограничений хозяйственной деятельности как, собственно, и в их пространстве, так и на окружающих территориях. Определению типологических характеристик и общих подходов к охране рукотворных и природных объектов культурного наследия, а также выделению зон охраны и регламентных ограничений на окружающих эти объекты территориях посвящена настоящая статья.
Развитие методов прогнозирования долговечности строительных конструкций на основе разработки теории и моделей коррозии бетонов с учетом явлений тепломассопереноса и формирования градиентных состояний
Authors: Чернышов Евгений , Федосов Сергей , Румянцева Варвара
Published: April 2023

Светлой памяти академика РААСН, доктора технических наук, профессора Евгения Михайловича Чернышова (17.07.1936 - 03.10.2021)

В статье представлены результаты научных исследований и инженерных разработок, связанных с теоретическими и экспериментальными исследованиями процессов массопереноса при коррозии бетона и железобетона в жидких агрессивных сре­дах. Исследуются проблемы долговечности и надёжности строительных конструкций, разрабатываются научные, методологические основы и средства решения таких проблем. Изучается кинетика и динамика развития процессов коррозии бетона и железобетона, которая позволяет определять условия возникновения деструктивных процессов, причины их ускорения или ослабления, разра­батывать математический аппарат для описания и прогнозирования развития коррозионных процессов, что в совокупности даёт возможность управления процессами коррозионной деструкции строительных материалов и конструкций. Разработаны математи­ческие модели, описывающие процессы коррозии железобетона в жидких средах различной степени агрессивности. Предложена новая теория прогнозирования процессов коррозии железобетона на основе феноменологических уравнений массопереноса и теории управления потенциалом коррозионной стойкости конструкции. Устанавливаются сроки накопления в бетоне достаточного для развития коррозии арматуры количества агрессивных веществ при различных условиях воздействия.
Comunicação e acessibilidades: um guia para práticas hospitaleiras
Authors: Caldas Pessoa Sônia , Mantovani Camila , Salgueiro Marques Ângela , Pereira Jácome. Phellipy
Published: April 2023

Por mais que uma pessoa sem deficiência faça o exercício de imaginar situações de acessibilidades em produtos midiáticos, processos de produção e práticas de recepção, interpretação, circulação e compartilhamento das mensagens e conteúdos, dificilmente vai chegar próximo das necessidades de alguém cuja deficiência impõe limites para ver, ouvir, compreender, sentir, se movimentar... Talvez esse seja um desafio imposto aos profissionais de comunicação: traçar caminhos em direção a produtos de mídia acessíveis sem poder ter certeza de que estão efetivamente contemplando as necessidades de alguém. Mas se não tentarmos, como saberemos que as regras de acessibilidade podem fazer uma diferença significativa para milhares de pessoas? E se não acreditamos na relevância, nos privamos de buscar alguns atalhos, com dicas práticas, e o caminho pode ser mais longo. Movidos pela utopia de tocar profissionais, estudantes e professores de comunicação para um olhar cuidadoso para a sua própria produção midiática nos encorajamos e seguimos os nossos guias. Estes sim, sujeitos inspiradores não pela deficiência, mas pela provocação que nos apresentam. Pessoas com deficiência cujos depoimentos estão neste livro foram, espontaneamente, nos abrindo caminhos, nos acompanharam e nos dirigiram em direção a um aprendizado necessário: ouvir o outro, saber que a sua existência não é igual às de tantos outros, e de algum modo compreender a complexidade da comunicação para diferentes grupos ou pessoas que estão, por conta da deficiência à margem de um público imaginado
Urinary Incontinence in Pregnancy and after Childbirth
Authors: Popovicova Maria , Babecka Jozef
Published: April 2023

Introduction: The development of incontinence depends on many factors and more often affects women who have already given birth. It is related to the growth of the fetus and the pressure of the head and fetus on the bladder and pelvic floor muscles. Hormonal influences also play an important role, as they relax the muscles and also affect the pelvic ligament. Due to this fact, in the research, we investigated urinary incontinence in a selected research sample and determined the degree of connection between incontinence of the respondents and factors such as pregnancy, number of births and the method of delivery. Methods: Using Microsoft Excel, we performed a mathematical-statistical evaluation of the data, which we expressed as a percentage in the attached graphic and tabular processing. We verified the hypotheses with the correlation coefficient, the Spearman coefficient and the non-parametric Kruskal-Wallis test. We made the decision about the existence of statistical significance based on the calculated p value and the significance level of 0.05.                                                      Results: By processing the results, we pointed out the degree of connection of urinary incontinence with several factors, namely pregnancy, the method of delivery and the number of births. For stress and overflow incontinence, the differences between the groups are very small. In urge incontinence, the differences are more pronounced between means and the mean ranks. However, even here, significant difference between the groups was not confirmed. Also, the connection between the number of births and urinary incontinence was not confirmed. However, we found a connection between the method of delivery and overflow and urge incontinence. Conclusion: Urinary incontinence during pregnancy and after childbirth is a significant burden for a woman. It covers the issues of the women it concerns in all spheres of life. Urinary incontinence is a certain burden for the whole society, not only for the affected woman. Therefore, one cannot forget exact drug therapy and other conservative treatment procedures, including the often underappreciated special therapeutic gymnastics – pelvic floor strengthening.
Modelo de la conducta planificada para la promoción del turismo civilizado: caso Villa de Leyva (Boyacá, Colombia)
Authors: Neme-Chaves Samir Ricardo , Forero-Molina Sara Catalina , Lesmes Ortiz Lizeth Viviana
Published: April 2023

El comportamiento del turista en los destinos es un factor relevante de la planificación turística y de gestión de los territorios, buscando con ello generar procesos de desarrollo económico alineados con la sostenibilidad ambiental, social y cultural. No obstante, el crecimiento masivo del turismo en municipios como Villa de Leyva, en Boyacá (Colombia), presenta desafíos en el equilibrio de la actividad económica con la mitigación de problemas ambientales e impacto a la calidad de vida de los habitantes, provocados por los comportamientos incivilizados de los turistas. En este sentido, la presente investigación buscó evaluar los factores clave que influyen en los comportamientos civilizados de los turistas en el contexto de turismo en Villa de Leyva, a través del modelo de la conducta planeada, en la cual participaron 287 personas entre los dieciocho y setenta y seis años. La metodología aplicada se abordó a partir del análisis factorial confirmatorio y modelado de ecuaciones estructurales. Los resultados mostraron que el modelo tiene índices de ajuste adecuados, CFI 0.99, TLI 0.98, RMSEA 0.037. Finalmente, se evidencia que, tanto las actitudes como el control conductual percibido, influyen positiva y significativamente en la intención de comportamiento civilizado en el contexto de turismo de Villa de Leyva. Se discuten las implicaciones teóricas y de gestión de los hallazgos.
A Match Made in Rural: Interpreting Match Rates and Exploring Best Practices
Authors: Longenecker Randall , Oster Natalia V. , Peterson Lars , Andrilla C. Holly A. , Schmitz David F. , Evans David V. , Morgan Zachary J. , Pollack Samantha W. , Patterson Davis G.
Published: April 2023

Background and Objectives: Although rural family medicine residency programs are effective in placing trainees into rural practice, many struggle to recruit students. Lacking other public measures, students may use residency match rates as a proxy for program quality and value. This study documents match rate trends and explores the relationship between match rates and program characteristics, including quality measures and recruitment strategies.
Methods: Using a published listing of rural programs, 25 years of National Resident Matching Program data, and 11 years of American Osteopathic Association match data, this study (1) documents patterns in initial match rates for rural versus urban residency programs, (2) compares rural residency match rates with program characteristics for match years 2009-2013, (3) examines the association of match rates with program outcomes for graduates in years 2013-2015, and (4) explores recruitment strategies using residency coordinator interviews.
Results: Despite increases in positions offered over 25 years, the fill rates for rural programs have improved relative to urban programs. Small rural programs had lower match rates relative to urban programs, but no other program or community characteristics were predictors of match rate. Match rates were not indicative of any of five measures of program quality nor of any single recruiting strategy.
Conclusions: Understanding the intricacies of rural residency inputs and outcomes is key to addressing rural workforce gaps. Match rates likely reflect challenges of rural workforce recruitment generally and should not be conflated with program quality.
Antibiosis, Chronic Pharyngitis Mitigation and Toxicology of Astragalus bhotanensisi
Authors: Xu-Dong * , Yang Ai , Huang Ying , Tao Yu-Xuan , Tang Rui-Dan , Yang Lan-Kun , Xiao Yan-Fen , Xiong Chen-Rui , Yao Ting , Yu Qiu-Man , Zhang Yi , Yang Xing-Xin
Published: April 2023

In China, Astragalus bhotanensis Baker (AB) has been used for
thousands of years and used to treat chronic pharyngitis (CP). In this
study, the disk diffusion method was used to assess the antibacterial
activities of AB on four bacterial strains. A rat model of CP induced by
β-hemolytic streptococcus (HS) was used to evaluate the ability
of AB against CP and its underlying mechanism. Mice were administrated
AB at a dose of 20 g/kg, and the survival status, organ index and
histopathology, blood routine and biochemistry were measured to evaluate
the toxicity of AB. Our results show that AB inhibited the growth of HS,
Diplococcus pneumoniae, Staphylococcus aureus, and
Escherichia coli. AB decreased serum levels of CRP, PEG2, TNF-α,
COX-2, MCP-1, 5-HT, ICAM-1, IL-6, LTC4, and IL-1β. AB reduced
infiltration and diffusion of pharyngeal inflammatory cells. AB also
decreased the expression of phosphorylated p38 and NFкB, and TLR4 in the
throat tissue. At a dose of 20 g/kg AB, routine blood levels and
biochemistry were not significantly different. In addition, AB increased
the spleen index of mice, but other organ indexes and histopathology
were not pathological changes. Our data indicate that AB alleviated
HS-induced CP by inhibiting inflammatory responses, which may be
involved with regulation of TLR4/p38MAPK/NFкB pathway. A dose of 20 g/kg
of AB did not exhibit toxicity in mice, except for the potential
toxicity to spleen, and may be the maximum tolerance of mice. AB
therefore offers a novel strategy to inhibit inflammatory responses to
further alleviate CP.
Reduction of Geomagnetically Induced Current Impacts by Optimized Neutral Point Connections
Authors: Schachinger Philipp , Albert Dennis , Renner H.
Published: April 2023

Solar storms impact electrical power grids by causing DC neutral point
currents in transformers. These currents lead to half-cycle saturation
as well as other related and unwanted effects in the grid. To reduce the
effect of these currents on the grid, DC-blocking devices can be
installed or changes in the grid topology can be made. However, these
counter measures often have unwanted side effects or cannot be applied
to the grid due to operational restrictions. In this work, a novel
mitigation approach, based on the distribution of currents on more
transformers, is presented. The number and location of grounded
transformer neutral points is optimized, taking grid related constraints
such as the minimal number of transformer connections into account. It
is shown that the algorithm can effectively reduce the stress on
transformers without any additional assets and thus increase system
security.
The Irminger Gyre as a key driver of the subpolar North Atlantic overturning on monthly timescales
Authors: Sanchez-Franks Alejandra , Holliday N. Penny , Evans Dafydd Gwyn , Fried Nora , Tooth Oliver John , Chafik Léon , Fu Yao , Li Feili , Jong Marieke Femke de , Johnson Helen Louise
Published: April 2023

The lower limb of the Atlantic meridional overturning circulation (AMOC)
is the equatorward flow of dense waters that have been transformed due
to the cooling and freshening of the poleward-flowing upper limb. In the
subpolar North Atlantic (SPNA), upper limb variability is primarily set
by the North Atlantic Current, whereas lower limb variability is less
well understood, particularly at subseasonal timescales. Using
observations from a SPNA mooring array, we show that variability of the
AMOC’s lower limb is connected to poleward flow in the interior Irminger
Sea. We identify this flow as the northward branch of the Irminger Gyre
(IG), accounting for 55% of the AMOC’s lower limb variability on
monthly timescales. Further, wind stress curl fluctuations over the
Labrador and Irminger Seas drives the IG and AMOC variability on monthly
timescales. On interannual timescales, however, increasing thickness of
intermediate water within the Irminger Sea coincides with decreasing IG
recirculation.
Data-Driven Equation Discovery of a Cloud Cover Parameterization
Authors: Grundner Arthur , Beucler Tom , Gentine Pierre , Eyring Veronika
Published: April 2023

A promising method for improving the representation of clouds in climate
models, and hence climate projections, is to develop machine
learning-based parameterizations using output from global
storm-resolving models. While neural networks can achieve
state-of-the-art performance, they are typically climate model-specific,
require post-hoc tools for interpretation, and struggle to predict
outside of their training distribution. To avoid these limitations, we
combine symbolic regression, sequential feature selection, and physical
constraints in a hierarchical modeling framework. This framework allows
us to discover new equations diagnosing cloud cover from coarse-grained
variables of global storm-resolving model simulations. These analytical
equations are interpretable by construction and easily transferable to
other grids or climate models. Our best equation balances performance
and complexity, achieving a performance comparable to that of neural
networks ($R^2=0.94$) while remaining simple (with only 13
trainable parameters). It reproduces cloud cover distributions more
accurately than the Xu-Randall scheme across all cloud regimes
(Hellinger distances $<0.09$), and matches neural networks
in condensate-rich regimes. When applied and fine-tuned to the ERA5
reanalysis, the equation exhibits superior transferability to new data
compared to all other optimal cloud cover schemes. Our findings
demonstrate the effectiveness of symbolic regression in discovering
interpretable, physically-consistent, and nonlinear equations to
parameterize cloud cover.