bluuebunny/crossref_metadata_2025 huggingface dataset:
Differential expression of USP54 in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding ubiquitin specific peptidase 54, USP54, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. USP54 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of USP54 in primary tumors of the breast was correlated with overall survival in patients with basal and HER2+ subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. USP54 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Psychische Gesundheit von LGBT*-Jugendlichen in Österreich: Scoping Review und Forschungsempfehlungen auf Basis internationaler Evidenz [Mental health of sexual and gender minority youth in Austria: Scoping review and research agenda based on international evidence]
Authors: Siegel Magdalena , Noestlinger Christiana , Dürrauer Flo , Kirchner Stefanie , Niederkrotenthaler Thomas , Zemp Martina
Published: August 2022

A robust body of international evidence documents that lesbian, gay, bisexual, transgender, and other youth with diverse sexual orientations and/or gender identities (i.e., sexual and gender minority youth) face unique mental health vulnerabilities but are also equipped with unique resources. However, it is unclear to what extent these findings are applicable to sexual and gender minority youth in Austria, because the sociolegal and developmental contexts differ across countries. According to PRISMA guidelines, we conducted a systematic scoping review (1) to identify published studies on the mental health of sexual and gender minority youth in Austria, and, based on this, (2) to derive research recommendations supplemented by international evidence. We searched five scientific databases (PsycInfo, PSYNDEX, PubMed, Scopus, Web of Science; March 2022) and additionally contacted researchers and community leaders to find pertinent studies. Only two published empirical studies on the mental health of sexual and gender minority youth in Austria could be located, reflecting the sparse state of research in Austria. Against this background, we outline a detailed research agenda following a socio-ecological approach. Including sexual orientation and non-binary gender identities in population-based studies to assess onset, prevalence, and trajectory of mental health burdens, as well as conducting targeted, resource-based, and developmentally sensitive research on all levels seem paramount to reduce health disparities and societal stigma and to support sexual and gender minority youth in their development.
Parents’ intention to vaccinate their children against COVID-19
Authors: Kentoš Michal , Kačmár Pavol , Vargová Lenka , Fedáková Denisa , Babjáková Jaroslava , Adamkovic Matus
Published: August 2022

Usually, parents and caregivers are the ones responsible for children's vaccination, their intention to vaccinate children depending on many factors. In a society where almost half of adults have refused to take a jab against COVID-19, it is important to know which factors increase or decrease the odds of a child getting vaccinated. In the present study, we examined parents’ reasons for/against children vaccination and predictors of this intention. We found that about 30% of parents intended to have their children vaccinated to protect the health of children and their close ones. On the other hand, parents who did not intend to have their children vaccinated were typically afraid of long-term consequences of vaccination and its side effects, with less than one fifth of them being skeptical about vaccination per se. Using logistic regression analyses, we found that a higher willingness to vaccinate was in male, older parents, and those with higher (socio)economic status. Parents with a higher adherence to restrictions, and higher trust in government and authorities were more likely to vaccinate their children. Moreover, parents who had themselves been vaccinated or were more positive towards vaccination in general were much more willing to vaccinate their children. On the contrary, belief in conspiracy theories decreased this intention 10-times. No other variables (e.g., demographic characteristics, mental health indicators, or direct experience with COVID-19) significantly predicted parents’ intention to vaccinate their children. The study offers several implications related to the complexity of factors which determine hesitant parents’ intention to vaccinate their children. We aimed to answer questions on how, when, and by whom parents should be approached to improve their awareness on vaccination decisions.
A time series analysis of group cohesion, group flow, and mood changes that occur throughout quasi-therapeutic singing sessions
Authors: Akagi Fumiho , Ichinose Tomoko , Takehara Naomi , Masuko Tsutomu , Kawase Satoshi
Published: August 2022

Introduction: Group singing sessions have been observed to result in positive mood changes. One reason for this mood enhancement property is the sense of unity generated by the resulting group cohesion. Based on this sense of unity, the concept of group flow is then likely related to the overall group’s cohesion to a certain degree. However, a question remains surrounding the time changes in the factors of group cohesion and flow during sessions in accordance with the therapist’s expectations. Method: To investigate this, quasi-therapeutic group singing sessions were employed. The present study conducted a time series analysis to examine changes in group cohesion, group flow, and participants’ moods by examining the influence of the song orders that a therapist used for effective mood enhancement. Results: The main findings were that (1) group singing sessions enhanced group cohesion and flow between members; (2) group cohesion and group flow of participants was altered in accordance with the order of the presentation of songs, as per our original expectation. Finally, we found that group singing sessions enhance participants’ positive mood through the resulting changes to the group cohesion and flow. Discussion: These results are applicable for those involved in the organizing of the structures of music therapy sessions, as well as future research into this therapeutic mode.
Psychosocial development is negatively correlated with political extremism
Authors: Martin Tim , Hartin Travis
Published: August 2022

Previous research indicates that in college samples there is a positive correlation between psychosocial development and economic conservatism. We tested the generality of this relationship with a nationally representative sample of respondents from the United States. The result was instead consistent with an alternative hypothesis that psychosocial development is related to political extremism. To our knowledge, this is the first report of an association between psychosocial development and political orientation.
Pengurangan Hasil Tangkapan Pada Alat Tangkap Togok dengan Menggunakan BRD (Bycatch Reduction Device) Tipe Rope BRD di Kuala Tungkal, Provinsi Jambi
Authors: Mauliddin Muhamad , Jhonnerie Romie , Nofrizal Nofrizal
Published: August 2022

Togok is a fishing gear in the form of a conical net body whose arms are on two poles and the success of catching it relies on currents, togok fishing gear is used to catch Rebon shrimp (Acetes japonicas) but in its operation, many catches are found bycatch. The high bycatch will have an impact on capture sustainable fisheries, one of the efforts to reduce bycatch is by using BRD (Bycatch Reduction Devices), the use of BRD has been widely carried out on trawl fishing gear but on togok fishing gear, it has never been done. This study aimed for knowing the reduction in catches of main catch, bycatch, and discard the togok fishing gear that has been installed with rope BRD and knows the reduction in catches of shrimp and fish species. This study uses experimental fishing, namely by carrying out direct fishing operations with local fishermen for 20 days of catch. The reduction of togok catch using BRD type rope BRD in the main catch is 8.4%, in bycatch is 11.8% and discard is 17, 1% and the reduction in catch of shrimp species ranged from 8,4% - 13,5% and reduction in catch of fish species ranged from 10,9% - 22,6%.
Strategi Komunikasi Lingkungan dalam Pelestarian Hutan Lindung pada Masyarakat Adat di Kenegerian Sentajo Kabupaten Kuantan Singingi
Authors: Rahmadi Rahmadi , Salam Noor Efni , Zulkarnain Zulkarnain
Published: August 2022

Kenegerian Sentajo protected forest serves as a protector of the community and natural life support systems, regulates water systems, prevents floods, controls erosion, and maintains soil fertility. The management of forest resources by the community is quite unique because it is still communally regulated, which is closely related to the kinship system and leadership of local indigenous peoples. This encourages the formation of strong communication relationships or interactions between communities and their forest resources. However, in reality, the indigenous people of Sentajo Regency have not obeyed the customary rules, which resulted in the forest that was originally preserved has begun to be converted to function by the community. The forest, whose precedence is beautiful, has now partially turned into plantation land and building houses for residents. This study aims to 1) Analyze environmental communication planning in the preservation of the Kenegerian Sentajo protected forest in Kuantan Singingi Regency; 2) Analyze the implementation and evaluation of environmental communication in the preservation of the Kenegerian Sentajo protected forest in Kuantan Singingi Regency. This research uses qualitative methods. Data collection techniques are carried out through interviews, observations, and documentation. Informants totaled 8 (eight) purposively determined persons. The data analysis technique used in this study is carried out in several stages, namely data reduction, data presentation and drawing conclusions, and testing the validity of the data using triangulation. The results of this study show that: First, the planning stage begins with an assessment which includes analyzing the situation and identifying the problem of environmental damage that occurs, Analysis of parties or actors involved, Then, planning which includes developing communication strategies, motivating and mobilizing communities with the division of indigenous territories and the selection of media and communicators. Second, this implementation stage begins with the production stage, which includes the design of the message to be delivered. Furthermore, the implementation stage is in the form of the application of customary norms, the application of socio-cultural values, and community empowerment through tree and rattan planting, their implementation, and documentation after evaluation.
Strategi Pengendalian Pencemaran Sungai Siak yang Berkelanjutan Menggunakan Pendekatan Multi Criteria Decision Making (MCDM)
Authors: Suprayogi Imam , Fauzi Manyuk , Alfian Alfian , Suprasman Suprasman , Nurdin Nurdin , Zulkifli Zulkifli
Published: August 2022

The main objective of the research is to establish a sustainable Siak River pollution management strategy, in an effort to accelerate (quick win) the strategic policy of Siak River pollution management which is one of the National Strategic category rivers located in the Sumatra Region based on Presidential Decree No. 12 of 2012 concerning the Determination of the River Basin, because the Siak River has a very large function and role in regional and economic development both locally, regionally and nationally. The approach method used is Multi Criteria Decision Making (MCDM) with the selected method of Analytical Hierarchy Process (AHP). The primary data is in the form of questionnaire data with the aim of being assessed by experts (expert judgment) who are considered competent in assessing the processing of Siak River pollution. Seven respondents identified who have the potential and are representative to contribute to obtaining expert judgment recommendations consist of Universities represented by the University of Riau (UR), the Riau Province Environmental Agency (BLH), the Sumatran Ecoregion Development Control Center, Non-Governmental Organizations (NGO) Jikalahari, Center for Watershed Management (BPDAS) Indragiri Rokan. Regional Research and Development Agency for Riau Province and the River Basin Center (BWS) III Sumatra.            The main results of the study stated that the Siak River water pollution control strategy using the AHP approach sequentially was to rearrange the spatial function, determine the pollution load capacity (DTBP), coordination of stakeholder synergies, program socialization and counseling, supervision and monitoring, law enforcement and development. Wastewater Treatment Plant (WTP).
Impact of Human Body Dissection on First Year Undergraduate Medical Students
Authors: Shah Sandip , Koirala Sarun , Khanal Laxman , Baral Presha
Published: August 2022

Background: The first contact with the dissection hall is an unforgettable, stressful but important step in the medical education. The present study aimed to assess the stress experienced just after one week of first dissection (IES1) and compare it with impact after 12 weeks (IES2) of first experience.
Methods: In this prospective cohort study, we enrolled 100 first year medical students of B. P. Koirala Institute of Health Sciences attending the cadaveric dissection. The questionnaire for Impact Event Scale (IES) was administered on two separate occasions after the human body dissection. Along with overall score for impact event, we also assessed the sub-scores of Intrusion and Avoidance.
Results: The percentage of students having clinically important reaction (a score of 20 or above) after one week of first cadaveric dissection in both sub-scales of Intrusion and Avoidance were 2% and 6% respectively but were found to be reduced to 1% each after 12 weeks. The overall scores indicating traumatic stress reaction was found to be reduced to 2% from 8%. The comparison between IES1 and IES2 using Wilcoxon signed ranked test showed statistically significant difference (p < 0.001). The bivariate correlation analysis between IES 1 and IES 2 showed positive correlation with statistically significant level (rs = 0.25; p < 0.001).
Conclusion: Overall score in students having traumatic stress reaction dropped by 6% after 12 weeks. The stress related to the human body dissection with respect to both Intrusion and Avoidance sub-scales in medical students reduced after the period of 12 weeks of first cadaver dissection.
Median Nail Dystrophy due to Habit Tic: A Case Report
Authors: Baaniya Bibisha , Shah Nidhi
Published: August 2022

Median dystrophy of nails may present with diagnostic difficulty. We present a case of a 30-year old male with multiple serial transverse ridges involving the median part of the bilateral great toe nails and the right thumb nail of approximately 10 years duration. On probing, the patient was found to have the habit of picking over the proximal nail folds. Habit of tic may not be noticed by the patient, however, may be the cause of dystrophy of nails.
Mucormycosis in COVID-19 Patients: A Hospital-based Study
Authors: Gurung Kishor , Pant Prabesh , Pokhrel Sandeep , Neupane Dhan Raj , Gurung Samjhana
Published: August 2022

Background: Fungal infections are increasingly being seen and mucormycosis is increasingly being isolated in COVID-19 patients, especially in those needing prolonged hospitalization. This cross-sectional study was carried out to isolate different fungi and identify their species in COVID-19 patients admitted for more than one month.

Methods: Sputum samples were taken from all the consecutive COVID-19 patients admitted in the hospital for more than one month and their health condition not improving despite the administration of antibiotics during May to July 2020. The samples were subjected to 10% KOH mount and Gram’s stain, and cultured onto Sabouraud Dextrose Agar. This was visualized under direct microscopy. Fungus was identified based on its morphology.
Results: Out of the 100 patients enrolled during the study period, 74 were male and 26, female. The different species of fungi were isolated from eight samples (8%) out of which two cases were confirmed to be mucormycosis (2%).
Conclusion: We conclude that fungal infections, including mucormycosis, are not uncommon in post-COVID patients with long-term hospital stay. We recommend that the investigation and identification of fungus may be routinely followed.
Let's Promote Clinical Trials
Authors: Gyawali Rajesh
Published: August 2022

Not available
Devastating Outcome of Late Onset Preeclampsia in a Multiparous Woman: A Case Report
Authors: Khatiwada Sindhu , Nepal Muna
Published: August 2022

Late onset preeclampsia may occur nascently in a multiparous woman. Although, early onset preeclampsia is associated with more adverse maternal and perinatal outcomes, late onset type in a multiparous woman can occur unexpectedly, and may progress rapidly to a life threatening situation. We report a case of late onset preeclampsia with HELLP syndrome and intracranial haemorrhage in a multiparous woman, who succumbed to death during the course of her treatment. We conclude that preeclampsia is a potential threat for dreadful outcomes, irrespective of its type, parity and duration of onset.
Evaluation of the Diagnostic Utility of Spinal Magnetic Resonance Imaging in Low Back Pain Patients
Authors: Sharma Bhoj Raj , Singh Sushma , Timilsina Madhu Maya
Published: August 2022

Introduction: Low back pain secondary to degenerative disc disease is a condition that affects young to middle-aged persons with peak incidence at approximately 30-39 years. Magnetic Resonance Imaging (MRI) is the standard modality for detecting disc pathology. This study is being conducted to review the pattern of spinal degenerative diseases in patients referred to our institution.
Methods: A retrospective study was conducted at Gandaki Medical College Teaching Hospital & Research Centre (GMCTHRC) from January 2018 to April 2018 with approval from the Institutional Review Committee of Gandaki Medical College Teaching Hospital and Research Centre. The MRI findings were noted i.e. disc desiccation, disc bulge (diffuse, symmetrical and asymmetrical), disc protrusion, neural foramen narrowing, traversing nerve root compression, exiting nerve root compression and posterior annular ligament tear.
Results: Out of 98 patients enrolled in the study mean age being 41 years. Disc bulge as most common finding seen in 89 (90.8%) followed by protrusion 50 (51.1%) neural foraminal narrowing (NFN) 72 (73.4%) traversing nerve roots (TNR) compression 58 (59.1%) and exiting nerve root (ENR) compression 22 (22.4%).
Conclusions: The study shows that degenerative disc diseases remain the cause of morbidity in the most productive years of life (30-40 years). Large volumes of MRIs performed for this condition represent a significant economic and healthcare burden in a developing country like Nepal.
Evaluation of the Diagnostic Quality of Chest Radiographs
Authors: Suwal Sundar , Koirala Surakshya , Chataut Dinesh
Published: August 2022

Introduction: With the advancement of conventional radiography to digital, digital radiography of the chest is commonly performed these days. The role and importance of diagnostic quality of radiographs are to help the radiologists and the clinicians in the diagnosis of diseases and their management, as well as to prevent the misdiagnosis of any pathology. This study was an attempt to quantify the diagnostic quality of chest radiographs by evaluating the quality of depiction of the anatomical details as well as other technical factors.
Method: A total of 450 chest radiographs, produced at Tribhuvan University Teaching Hospital, were selected for study over two months period. Five image quality criteria i.e. anatomical coverage, rotation, adequate penetration, adequate inspiration, and scapula out of lung fields were evaluated and tabulated.
Results: Out of the 450 radiographs taken for study, only 22.2% of the radiographs fulfilled all the image quality criteria, the rest 77.8% either lacked one or more of the quality criteria.
Conclusion: Many technical factors affect the image quality of digital chest radiographs. However, the radiographer/technologist should always try to maintain adequate image quality of the radiographs.
Complications of Ultrasonography Guided Percutaneous Renal Biopsy in Children: A Retrospective Study in a Tertiary Hospital in Nepal
Authors: Devkota Karun , Yadav Shankar Prashad , Adhikari Bijay
Published: August 2022

Introduction:  Percutaneous renal biopsy is done under ultrasonographic guidance in recent times due to which the diagnostic yield has increased and complications have been severely curtailed. We aimed to retrospectively evaluate the complications following kidney biopsy in children.
Methods: After obtaining ethical clearance, retrospective evaluation of sixty pediatric renal biopsies done in BPKIHS from October 1, 2018, to September 30, 2020, were included in the study. Biopsies were done by 18G biopsy guns under ultrasound guidance and the complications were evaluated.
Results: Of sixty patients, 13.33% had gross hematuria, 3.33% had a perirenal hematoma and the biopsy failure rate was 3.3%. None of the patients required blood transfusion and had major complications requiring further intervention.
Conclusions: Percutaneous renal biopsy under ultrasonographic guidance is a safe procedure with a better success rate.
Incidence of Ectopic Pregnancy and its Diagnostic Accuracy by Clinical, Ultrasound and Intraoperative Findings
Authors: Shrestha Shreejana , Dwa Yogita , Jaiswal Pooja , Maharjan Dinesh , Karki Prabhat , Shrestha Sarada Duwal
Published: August 2022

Introduction: In an ectopic pregnancy, most patients present with 5 to 9 weeks of amenorrhea, mild pelvic pain and vaginal spotting which triggers the evaluation of ectopic pregnancy. The presence of an extrauterine gestational sac containing a yolk sac or embryo is the most specific sonographic finding whereas an echogenic tubal ring in the adnexa is the most common finding.1  This study aimed to find the accuracy of ultrasound findings versus clinical presentation, intraoperative findings and histological findings.
Methods: This is a retrospective study. All patients with histopathological diagnoses of ectopic pregnancy were included in the study and data regarding clinical diagnosis, ultrasound diagnosis and intraoperative diagnosis were retrieved and compared with their histopathological diagnosis.
Result: There were 216 cases of ectopic pregnancy with an overall incidence of ectopic pregnancy was 0.88%. The sensitivity with ultrasound diagnosis was 99.52% and specificity 11.11% with positive and negative predictive values were 96.2 % and 50 % respectively and overall diagnostic accuracy of 95.83%. The sensitivity was 97.6% and specificity was 11.1% for clinical diagnosis of ectopic pregnancy. The sensitivity was 100% for intraoperative diagnosis of ectopic pregnancy with a positive predictive value is 95.83%.
Conclusion: Clinical diagnosis, intraoperative findings and ultrasound findings were highly sensitive to detecting ectopic pregnancy in the study population. The overall diagnostic accuracy was highest for the ultrasound finding.
Comparison of Actual Birth Weight with the Ultrasonographic and Clinical Estimation of Fetal Birth Weight: A Prospective Study
Authors: Gurung Sangeeta Devi , Shrestha Junu , Gauchan Eva , Subedi Anjali , Shrestha Aashika , Thapa Sudikshya
Published: August 2022

Introduction: Determination of fetal weight is important for the management during labour and delivery. It helps in determining the mode of delivery and aids in diagnosing low birth weight, macrosomia, and intrauterine growth restriction fetus. Ultrasound may not be available in under-resourced settings. Therefore, it is important to study the accuracy of clinical estimation of fetal weight with the sonographic and actual birth weight.

Methods: One hundred and fifty women fulfilling the inclusion criteria were enrolled for the study. Clinical estimation of fetal weight was done by using the Johnson formula. Then the women were subjected to ultrasound. Sonographic estimation of fetal weight was done by the Hadlock method. The two estimated fetal weights were then compared with the actual birth weight. Data were analyzed using SPSS (VERSION 16).

Results: Actual birth weight has a strong correlation with the ultrasonographic birth weight (p=0.01). However, the clinical birth weight estimation was less correlating to the actual birth weight (p=0.638)

Conclusion: The ultrasound method is better in determining the actual birth weight as compared to the clinical method. Hence, ultrasound has to be recommended whenever available.
Speech-language Pathologist: A Team Member for Management of Head and Neck Cancer Patients
Authors: Bhattarai Biraj
Published: August 2022

Head and Neck cancer is one of the most prevalent conditions in the world and so is in Nepal. Head and Neck cancer causes speech, language, and swallowing disorder that affects the quality of life of a patient. A multidisciplinary team is needed for the management of the cancer patient. A Speech Language Pathologist is one important team member involved in the rehabilitation of communication and swallowing issues. The role of Speech Language pathologists should be understood by other medical professionals and need to be integrated into the team to provide a holistic health care facility to an individual with head and cancer.
Causes of Blindness and Visual Impairment Among Children Studying in Schools for the Blind in Central Development Region of Nepal
Authors: Shrestha Jyoti Baba , Adhikari Pragati Gautam , Shrestha Gauri Shankar
Published: August 2022

Introduction: This study was done to find out the causes of visual impairment in students studying in schools for the blind in the central development region of Nepal.
Materials and Methods: The study was done in six schools for the blind in the central development region of Nepal. It was conducted by a team of Eye care professionals using standard eye examination protocols of the World Health Organization Prevention of Blindness Program in the year 2009.
Results: A total of 133 students (5 - 21 years age group) enrolled in six schools for the blind were examined. 52.6% of children were visually impaired at birth and 12% developed vision impairment within one year of age. Twenty-one students (15.8%) had mild visual impairment, 5 students (3.8%) had severe visual impairment and 101 students (76%) were blind. The main cause of vision impairment was found to be lens-related anomaly 23.3% and retinal diseases, 18% followed by corneal lesions, 16.5%, and problems with the whole globe, optic nerve, and glaucoma accounting for 12.03%, 11.3%, and 7.5% respectively. The etiology could not be identified in 48.1% followed by hereditary causes (31.6%) and childhood factors (12%). Of the total students examined, 37.6% were visually impaired due to avoidable causes; preventable in 22.6% and treatable in 15% of cases.
Conclusions: A high proportion of childhood blindness in schools for the blind in the central development region of Nepal is avoidable.
Use of Brain Stimulation to Improve Swallowing in a Brainstem Stroke Patient with Cricopharyngeal Spasm: Case Report
Authors: Sanghavi Tanvi
Published: August 2022

In India, post-stroke dysphagia affects between 37 and 78 percent of people. In recent years, research into transcranial magnetic stimulation has enhanced our understanding of the neurological aspects of swallowing, thanks in great part to Hamdy and colleagues' pioneering work. TMS has been shown to help with depressive symptoms, anxiety, and parkinsonian symptoms, however, there is no study on how it can help with swallowing. This case study looked at the effects of transcranial magnetic stimulation and transcranial direct current stimulation in combination with standard swallowing training on swallowing function in brainstem stroke patients with cricopharyngeal spasms.
Comparative Study of Modified Alvarado Score and Eskelinen Score in Diagnosing Acute Appendicitis
Authors: Dahal Isha
Published: August 2022

Introduction: Despite many advances in diagnosis, diagnosing appendicitis remains difficult. Various diagnostic scoring systems have been developed in an attempt to improve the diagnostic accuracy of acute appendicitis. The study aimed to determine the accuracy of the Modified Alvarado and Eskelinen score in diagnosing acute appendicitis and to correlate the histopathological findings with the severity of acute appendicitis.
Materials and Methods: A prospective study was conducted in TUTH including 84 patients with a clinical diagnosis of acute appendicitis managed surgically for 10 months. Modified Alvarado and Eskelinen Score were calculated and histopathological findings were correlated for predicting the severity of appendicitis.
Results: Out of 84 patients  Modified Alvarado Score had sensitivity and specificity of 67.79% and 32% when the score was taken as 7  and Eskelinen Score had sensitivity and specificity of 70.17% and 29.62% when the score was taken as 55. However, the sensitivity of the Modified Alvarado Score increased to 92.85% and specificity to 14.28% when the cut-off score was taken as 6. Modified  Alvarado Score predicted 67% and 63% of uncomplicated and complicated appendicitis respectively and Eskelinen Score predicted 72% of uncomplicated and 67% of complicated appendicitis when the score was taken as 7 and 55 respectively.
Conclusions: Both Modified Alvarado and Eskelinen Scores have low sensitivity in diagnosing acute appendicitis. With cut off for Modified Alvarado Score taken as 6, sensitivity increased. There was no correlation between the severity of appendicitis with the increase in Modified Alvarado and Eskelinen Score.
Recurrence of Renal Hydatid Cyst
Authors: Basnet Robin Bahadur , Regmi Prabodh , Adhikari Baikuntha , Gharti Binod Babu , Basnet Surendra , Mishra Udita
Published: August 2022

Hydatid cyst is a zoonotic disease caused by Echinococcus granulosus, transferred through the oral-fecal pathway by eating vegetables and food contaminated with dog stool containing eggs of the parasite. Hydatid cyst is most commonly found in the liver; however, dissemination can occur in other organs such as the lung and rarely in the heart, breast, thyroid, soft tissue of the neck, and kidney. The surgical approach remains the treatment of choice in hydatid. Meticulous handling of hydatid is important preoperatively and care should be taken against spillage of the contents and daughter cysts. In this case report, we report a case of recurrence of renal hydatidosis.
Comparative Study of Clinical Profile and Outcome Among Variceal and Nonvariceal Bleeding in a Tertiary Referral Hospital of Nepal During Covid Pandemic
Authors: Karki Binod , Sherpa Tshering Wagdi , Deo Rajeeb Kumar , Aryal Egesh , Regmi Binit Upadhyaya , Adhikari Alisha , Katawal Srijana , Mandal Sujit Kumar
Published: August 2022

Introduction: Upper Gastrointestinal Bleeding is a common medical emergency that is broadly classified into variceal and non-variceal bleeding. Preendoscopicemperical treatment is based on clinical findings and laboratory parameters. The article aimed to compare these parameters among variceal and non-variceal bleeding.
Materials and Methods: This is a retrospective descriptive study conducted in a tertiary level referral hospital after taking approval from the Institutional review board. The data included was from September 2020 to August 2021. All patients with relevant data who underwent upper GI endoscopy were enrolled. The clinical and laboratory parameters were compared using appropriate statistical tests.
Results: A total of 85 patients were studied with 40 (47.06%) in the variceal and 45 (52/94%) in the non-variceal group. Significantly more patients in the variceal bleeding group had a history of alcohol consumption (85% vs 60%) and smoking history (52.50 % vs 31.10%) compared to the non-variceal group. Jaundice, ascites, splenomegaly, low platelet count, and high INR all were predictors of variceal bleeding (p<0.005). In the variceal group, 39 (97.5%) needed endo therapy compared to only 4 (8.9%) in the non-variceal group.
Conclusions: Clinical and laboratory parameters differ significantly in the variceal and non-variceal groups which can guide the pre-endoscopic management of the patients.
The Milan System for Reporting Salivary Gland Cytopathology: A 3-year Retrospective Analysis in Patan Hospital
Authors: Gautam Dipti , Thapa Rojin
Published: August 2022

Introduction: The characteristics of salivary gland lesions identified by fine-needle aspiration cytology are varied and may overlap, which makes diagnosis difficult for cytopathologists. To provide consistency in the reporting of salivary gland cytology and to enhance clinic-pathologic communication, the "Milan system for reporting salivary gland cytopathology" has been introduced, which offers guidelines for diagnosis and treatment based on various categories of malignancy risk.
Material and Methods: In this retrospective study, Fine needle aspiration cytology was done for all salivary gland lesions for three years and were retrieved from the Department of pathology, Patan hospital. All the cases were recategorized according to the Milan system for reporting salivary gland cytology with histopathology follow-up wherever available. Consistency of the two different types of assessment techniques (Milan category and primary cytology diagnosis) were assessed and the k score was calculated
Results: A total of 58 cases were included in the study of which histological follow-up was available in 27 cases. Out of 58 cases, maximum cases 32 (55.1%) were classified under IVA followed by 15.5% cases classified under II, 8.6% of cases under Category IVB), 6.8% under category Vand 5.1% cases under category VI. Kappa's score was 0.58 which represents a moderate agreement.
Conclusions: Milan system for reporting salivary gland cytopathology is a recently proposed six-category scheme, which places salivary gland fine needle aspiration cytology into well-defined categories that limit the possibilities of false negative and false positive cases.
Risk Analysis Using Multi-Attribute Failure Mode Analysis Approach in Mybeb Social Payment Application
Authors: Adam Bob Maulana , Tarigan Zeplin Jiwa Husada
Published: August 2022

MyBeb is a social payment application owned by one of the FinTech companies in the Sidoarjo area, East Java Province. Mybeb itself is an application that provides social media features as well as payments. In running the product, several obstacles and operational risks arise that have not been handled properly, and not a few users have not been properly educated in the use of this application. This study aims to identify risk priorities and corrective actions that must be taken using the MAFMA method. The method is to detect failure points that have great potential to be overcome. Then get the results and benefits of the analysis method that will affect the company using the methods. From the methods, the risk with the highest value was at the risk of the P10 value, which was 0.482. At the same time, the lowest risk is at P1 risk with a risk level value of 0.251. Then for managerial implications for the proposed improvement to the method with the highest risk level at P10 risk, a page for a list of friends using referral links from users is given to those who have done uploading profile photos.
Fractional Gradient Based Optimization for Nonlinear Separable Data
Authors: Hapsari Dian Puspita , Fahrur Rozi Muhammad
Published: August 2022

The Support Vector Machine or SVM classifier is one of the machine learning algorithms whose job is to predict data. Traditional classifier has limitations in the process of training large-scale data, tends to be slow. This study aims to increase the efficiency of the SVM classifier using a fractional gradient descent optimization algorithm, so that the speed of the data training process can be increased when using large-scale data. There are ten numerical data sets used in the simulation that are used to test the performance of the SVM classifier that has been optimized using the Caputo type fractional gradient descent algorithm. In this paper, we use the Caputo derivative formula to calculate the fractional-order gradient descent from the error function with respect to weights and obtain a deterministic convergence to increase the speed of the Caputo type fractional-order derivative convergence. The test results show that the optimized SVM classifier achieves a faster convergence time with iterations and a small error value. For further research, the optimized SVM linear classifier with fractional gradient descent is implemented on the problem of unbalanced class data.
An X-Ray Tomography Primer
Authors: Levine Zachary H.
Published: August 2022

X-ray tomography has been rapidly gaining acceptance in the semiconductor industry since the first demonstration of its use on IC interconnect in 1999. As failure analysts are discovering, X-ray imaging is more powerful than visible light microscopy and can be used to analyze larger samples than those that fit in an electron microscope. This article provides an introduction to the physics, signal processing, and algorithms involved in X-ray imaging and tomography and the factors that affect resolution.
SOSIALISASI DAUR ULANG SAMPAH SEBAGAI UPAYA PENINGKATAN KESADARAN LINGKUNGAN PADA MASYARAKAT BANTARAN SUNGAI KAPUAS
Authors: Anggela Rika , Rina Rina , Rosanti Rosanti , Eviliyanto Eviliyanto
Published: August 2022

Tujuan dalam pengabdian masyarakat ini adalah dapat meningkatan kesadaran lingkungan pada masyarakat melalui sosialisasi daur ulang sampah rumah tangga pada masyarakat bantaran Sungai Kapuas di sekitar Gang H. Hasan Pontianak Tenggara. Metode dalam sosialisasi daur ulang sampah sebagai upaya peningkatan kesadaran lingkungan pada masyarakat Bantaran Sungai Kapuas dibagi menjadi 3 (tiga) tahapan yaitu, persiapan, pelaksanaan dan evaluasi. Kegiatan yang dilaksanakan meliputi sosialisasi tentang dampak yang ditimbulkan sampah, penyuluhan daur ulang sampah dengan melakukan praktek dalam daur ulang sampah non organik dan kegiatan edukatif-kreatif dalam bentuk perlombaan kreativitas daur ulang sampah. Segala kegiatan yang dilakukan berjalan lancar sesuai dengan target dan luaran yang telah direncanakan. Berdasarkan hasil angket diketahui bahwa kesadaran masyarakat terhadap lingkungan sebelum program pengabdian masuk kriteria Cukup persentase 43.75% dan setelah dilakukan program pengabdian berada pada kriteria Baik dengan persentase 15.6% dari 32 responden. Kegiatan yang dilaksanakan memberi gambaran bahwa kegiatan ini membawa peningkatan kesadaran terhadap lingkungan pada masyarakat meliputi Pengetahuan, sikap dan tindakan terhadap lingkungan khususnya sungai. Program ini juga memberi inspirasi kepada masyarakat bahwa sampah bukan akhir dari efektifitas suatu barang namun dengan daur ulang, sampah dapat menjadi barang yang lebih bernilai kreatif dan ekonomis.
EDUKASI MASYARAKAT TERKAIT KOSMETIKA AMAN DI DESA CIDATAR KABUPATEN GARUT JAWA BARAT
Authors: Sriarumtias Framesti Frisma
Published: August 2022

Kosmetika merupakan bagian penting dalam kehidupan wanita. Penggunaan kosmetika adalah untuk menyamarkan ketidaksempurnaan pada kulit. Tetapi sayangnya masyarakat belum bisa membedakan terkait kosmetika yang aman. Tujun dari perngabdian ini adalah untuk mengedukasi masyarakat terkait ciri-ciri kosmetika yang aman serta efek merugikan dari kosmetika yang tidak aman. Metode pengabdian kali ini yaitu dengan sosialisasi berupa pemaparan materi dilanjutkan dengan simulasi untuk melakukan cek nomor registrasi secara online di website BPOM serta dilakukan diskusi. Hasil pengabdian kali ini memberikan informasi kepada masyarakat bagaimana cara mengetahui kosmetika yang aman dan teregistrasi di BPOM. Kesimpulan dalam pengabdian kali ini masyarakat bisa melakukan cek registrasi melalui laman BPOM secara online.
PENYULUHAN DAN SOSIALISASI “CHILD TRAFFICKING” ANAK USIA SEKOLAH DI DESA SUNGAI BARU KECAMATAN TELUK KERAMAT KABUPATEN SAMBAS
Authors: Yuliananingsih Yuliananingsih , Novianty Fety , Firmansyah Syarif
Published: August 2022

Tujuan kegiatan ini adalah mensosialisasikan kepada anak atau remaja usia sekolah akan bahaya “child trafficking” yang merupakan salah satu tindak kejahatan terhadap anak. Kegiatan ini diharapkan memberikan manfaat agar anak-anak atau remaja mengetahui hak-hak mereka, sebagai anak dan manusia, agar anak mendapatkan pendidikan yang lebih layak dan tidak putus sekolah, agar anak-anak atau remaja juga mengetahui dan memahami Undang-Undang Perlindungan Anak, agar anak-anak atau remaja usia sekolah terhindar dari “child trafficking”. Metode yang digunakan dalam pelaksanaan kegiatan ini adalah sosialisasi dan penyuluhan tentang “child trafficking”, dampak putus sekolah, bahaya “child trafficking”, dengan memberikan contoh membawa salah satu korban dari “child trafficking” atau “human trafficking”. Hal-hal yang dapat dievaluasi dari kegiatan ini adalah respons anak-anak atau remaja usia sekolah terhadap sosialisasi dan penyuluhan ini, pemahaman anak-anak atau remaja usia sekolah terhadap bahaya“child trafficking”.
OPTIMALISASI PERAN DESA DALAM PENCEGAHAN PENYEBARAN COVID-19 DI DUSUN PRANGKO’AN KABUPATEN MAGELANG
Authors: Sasongko Dimas , Ulfah Maryatul , Ulfah Maryatul , Prihatiningsih Aris , Prihatiningsih Aris , Lestari Murni , Lestari Murni , Sodik Jafar , Sodik Jafar , Ardian Agit , Ardian Agit
Published: August 2022

Pencegahan dan penanganan pandemi Covid-19 menjadi tugas dan tanggung jawab bersama warga Desa Prangko’an. Selain penanganan penyebaran Covid-19 perangkat desa bertanggung jawab untuk mengatasi permasalahan perekonomian warganya. Tujuan kegiatan pengabdian yang dilaksanakan adalah membantu memberikan edukasi dan pencegahan penyebaran Covid-19. Diharapkan dengan adanya program Pengabdian Kepada Masyarakat penanggulangan Covid-19 di Desa Prangko’an dapat membantu mengoptimalkan program pencegahan penyebaran Covid-19. Metode penyelesain masalah dalam program Pengabdian Kepada Masyarakat terdiri dari pembuatan alat peraga seperti poster untuk edukasi tentang Covid-19 dan penanggulangannya, pendataan warga prioritas, pembagian sembako kepada masyarakat prioritas, penyemprotan desinfektan, pembagian masker, dan memberikan dana untuk membatu pembagian sembako gratis. Hasil kegiatan Pengabdian Kepada Masyarakat ini adalah warga Desa Prangko’an telah mendapatkan informasi dan edukasi tentang bahaya virus Covid-19; warga Desa Prangko’an telah mendapatkan informasi dan edukasi tentang cara pencegahan dan penaggulangan dari Virus-19; dan Desa Prangko’an menjadi Desa Tanggap Covid-19 yang siap untuk menjaga warga masyarakatnya dari pandemi Covid-19.
Seminar Pendidikan dalam Rangka Peningkatan Motivasi Siswa Kelas XII untuk Melanjutkan Pendidikan di Perguruan Tinggi
Authors: Wiguna Muhammad Zikri , Alimin A A
Published: August 2022

Pengabdian ini bertujuan untuk meningkatkan motivasi siswa-siswi kelas 12 SMA Pemangkat Kalimantan Barat masuk perguruan tinggi. Peserta pengabdian adalah seluruh siswa kelas XII SMA Negeri 1 Pemangkat. Metode pengabdian berupa seminar dan penyampaian materi oleh narasumber. Alat pengumpul data yang digunakan adalah angket motivasi siswa untuk melanjutkan ke jenjang perguruan tinggi. Hasil analisis angket dapat dilihat bahwa sebesar 22.2% siswa berminat melanjutkan ke perguruan tinggi. Berdasarkan temuan tersebut, disarankan agar sekolah selalu menginspirasi dan memberikan dukungan kepada para siswanya yang bersemangat dan mempunyai motivasi tinggi untuk melanjutkan pendidikan ke perguruan tinggi.
Pelatihan Recycle Kain Sisa Konveksi dengan Teknik Patchwork Quilting pada Remaja LKSA Rumah Pengharapan Baru
Authors: Putri Aulia W. A , Janty Tan Indra , Dennisa Lois , Permanasari Rosa , Oetomo Angel Octavia , Dafis Tasha Putri , Candra Graciella Natalie
Published: August 2022

Fast traslate Icon translate     Fast traslate Icon translate     Fast traslate Icon translate     Fast traslate Icon translate     Fast traslate Icon translate     Fast traslate Icon translate Pandemi Covid-19 ini menuntut semua lapisan masyarakat untuk memilikikesadaran yang tinggi akan kebersihan hingga pengendalian terhadap laju sampahdan limbah dengan tujuan menjaga dan memperpanjang umur bumi dan isinyadalam sebuah gerakan sustainable lifestyle. Limbah tekstil yang dihasilkan dalamproses produksi garmen dan konveksi yang tidak ditangani dengan baik menjadisalah satu penyumbang sampah industri khususnya di Kota Bandung. RumahPengharapan Baru merupakan sebuah Lembaga Kesejahteraan Sosial Anak(LKSA) yang memiliki misi mendukung dan melengkapi perkembangan anaksesuai bakat dan minatnya, hal ini sejalan dengan Program Studi D-3 Seni Rupadan Desain Universitas Kristen Maranatha yang aktif dalam kegiatan pengabdianmasyarakat dengan memberikan pelatihan kepada warga sekitar kampus maupun lembaga-lembaga yang membutuhkan. Pelatihan ini dilaksanakan untukmengasah keterampilan soft skill dan pengetahuan eksplorasi teknik pesertadengan metode praktik patchwork quilting pada kain perca sisa konveksi sehingga hal tersebut dapat menjadi bekal dalam pemanfaatan limbah tekstil secara mandiri untuk dikembangkan menjadi produk kreatif siap pakai yang memiliki nilai daya jual dan peluang dalam industri kreatif/wirausaha kecil rumah tangga.
Coaching Clinic Teknik Dasar Sepak Bola Bagi Anak-Anak
Authors: Jumain Jumain , Wahyudhi Andi Sultan Brilin S.E , Baan Addriana B , Agusman Agusman
Published: August 2022

Coaching clinic merupakan program pelatihan sepak bola singkat yang bertujuanuntuk meningkatkan pengetahuan dan keterampilan bermain sepak bola. Tujuandari program kegiatan Coaching clinic yaitu agar anak-anak SSB (Sekolah SepakBola) dapat meningkatkan pengetahuan dan keterampilan bermain Sepak Bola,terutama dalam aspek teknik dasar. Masalah dalam pengabdian ini adalah (1)masih rendahnya teknik dasar SSB Rauf Junior dan SSB Tunas Kaili, (2) masihrendahnya pengetahuan pelatih SSB terhadap pemberian latihan kemampuanteknik dasar bermain sepak bola. Metode yang digunakan dengan merencanakan, mengaktualisasi, mengontrol kegiatan coaching clinic dan melakukan pendampingan kepada mitra. Peserta dalam coaching clinic sepak bola dalam meningkatkan sumber daya manusia SSB sebanyak 30 orang peserta dari 2 SSB, yang dilaksanakan selama 3 hari. Hasil yang dicapai menambah wawasan peserta maupun pelatih dalam melakukan latihan, selain itu ada peningkatan motivasi, minat maupun gerakan teknik dasar bermain sepak bola dan ada peningkatan skill setiap individu peserta SSB.