bluuebunny/crossref_metadata_2025 huggingface dataset:
El tratamiento de la mitología en los dramas con música realizados para ámbitos privados en la primera mitad del siglo XVIII
Authors: Presas Villalba Adela
Published: April 2019

RESUMENAparte de las funciones teatrales y cortesanas, de gran aparato escénico, existió durante el siglo XVIII la costumbre de representar zarzuelas, y otros tipos de obras dramáticas con música, tanto en casas particulares como en ámbitos privados, escolares o culturales. Es además constatable que estas obras estuvieron siempre basadas en la mitología, y aunque este es un rasgo común en el teatro músico del siglo XVII y de la primera mitad del XVIII en España, es interesante observar si recibe, en este caso, un tratamiento diferenciado. En el presente artículo se plantea la interacción que se produce entre el elemento musical (formato y contenido textual) y la temática mitológica en estas obras dedicadas a un público diferente al de los teatros, ya sean cortesanos o populares, y para un entorno privado que contaba, además, con unas limitaciones evidentes tanto en el aspecto escenográfico como, especialmente, en el musical.PALABRAS CLAVEZarzuela, mitología, teatro musical español, siglo XVIII, funciones privadas. TITLEThe treatment of mythology in dramas with music made for private circles in the fi rst half of the 18th centuryABSTRACTApart from the theatrical and court performances, of great scenic apparatus, there was during the eighteenth century the custom of representing zarzuelas, and other types of dramatic works with music, both in homes as well as in private school and cultural areas. It is also verifiable that these works were always based on mythology, and although this is a common feature in the music theatre of the seventeenth century and first half of the eighteenth century in Spain, it is interesting to note whether it receives, in this case, a differentiated treatment. This article puts forward the interaction between the musical element (format and textual content) and the mythological subject in these works devoted to a different audience than that of the theatres, either court or popular, and for a private milieu which had, in addition, obvious limitations both in the scenography and, especially, in the musical features.KEY WORDSZarzuela, mythology, Spanish musical theatre, eighteenth century, private performance.
La tradición clásica en la obra poética de Manuel Fermín de Laviano. Apuntes para su estudio
Authors: Escalante Varona Alberto
Published: April 2019

RESUMENEn este artículo se propone un estudio de dos poemas de Manuel Fermín de Laviano como ejemplo de poemas de encomio, dentro de la tradición dieciochesca: los "Endecasílabos a los Infantes Gemelos" y el "Canto al Arco del Duque de Híjar". Se rastrea la influencia de la tradición clásica en la composición de estos textos. Para ello, se propone un modelo de análisis atendiendo a la incidencia genérica y relación cultural entre los textos clásicos y la literatura occidental moderna. A continuación, se comentan ambos poemas: editamos también el "Canto".PALABRAS CLAVEGenethliakón, géneros epidícticos, poesía de circunstancias, Carlos IV. TITLEThe Classical Tradition in Manuel Fermín de Laviano’s Poetic Texts. Some Notes for its StudysABSTRACTIn this paper, we study two poems by Manuel Fermín de Laviano, as encomium poems in the Spanish Enlightenment tradition: the "Endecasílabos a los Infantes Gemelos" and the "Canto al Arco del Duque de Híjar". We search for the influence of Classical Tradition in the writing process of these texts. For that purpose, we analyse both poems due to its generic characteristics and the cultural relationship between them and classical literature. At last, we comment them, and we edite the "Canto".KEY WORDSGenethliakon, epideictic genres, circumstances poetry, Charles IV.
Antonio T. REGUERA RODRÍGUEZ, «La carta geométrica. Los antecedentes del Mapa Topográfico Nacional», León, Universidad de León, 2017, 646 págs.
Authors: Alvargonzález Rodríguez Ramón
Published: April 2019

SIN RESUMEN
Francisco SÁNCHEZ-BLANCO, «"El Censor". Un periódico contra el Antiguo Régimen», Sevilla, Ediciones Alfar, 2016, 292 págs.
Authors: Urzainqui Inmaculada
Published: April 2019

SIN RESUMEN
EL DISEÑO DE INTERIORES EN EL CINE DE BILLY WILDER

Interior Design in Billy Wilder's Filmography
Authors: Argüelles Quirós Celia
Published: April 2019

Billy Wilder está considerado uno de los mejores directores de la Historia del Cine. Nacido a principios del siglo XX en el Imperio Austrohúngaro, a lo largo de su vida mantuvo una importante relación con el arte y el diseño. La valiosa colección de arte contemporáneo que llegó a atesorar y su amistad con el matrimonio de diseñadores Ray y Charles Eames, hace que resulte muy interesante analizar el diseño de interiores en sus películas. Este artículo supone un recorrido a través del hogar y los lugares de trabajo de la sociedad americana del siglo XX.
Диалектика Судного дня: гонка вооружений и их ограничения
Authors: Арбатов Алексей
Published: April 2019

Мир сомнамбулически бредет к принципиально новому этапу состояния международной безопасности – жизни в условиях гонки ядерных и иных вооружений безо всяких ограничений, правил и обмена военной информацией. Почти неизбежна денонсация Договора о ликвидации ракет средней и меньшей дальности (ДРСМД); Договор СНВ-3, скорее всего, не будет продлен после 2021 г.; предстоящая в 2020 г. очередная конференция по рассмотрению Договора о нераспространении ядерного оружия (ДНЯО) практически обречена на провал. Между тем важный опыт прошедшего полувека состоит в том, что отказ от договоров в этой сфере не укреплял безопасность государств, а всегда ослаблял ее. За это же время история 27 гонки вооружений дала немало примеров того, как первенство в создании нового оружия впоследствии оборачивалось для безопасности той или иной стороны большим ущербом, а не выигрышем. Самый главный урок заключается в том, что ядерное сдерживание может быть гарантией мира только в сочетании с сохранением и расширением системы и режимов договорно-правового контроля над ядерным оружием. Сегодня первоочередная задача – спасение Договора РСМД, что все еще возможно. Затем на очереди – соглашение о продлении Договора СНВ-3 после 2021 г. или срочное начало переговоров по следующему договору СНВ. После этого – меры по укреплению ДНЯО. Лишь последовательные шаги разоружения – параллельно с позитивными изменениями международной политической и стратегической среды – способны укрепить всеобщую безопасность в грядущем веке.
Interrelaciones entre el medio televisivo y los videojuegos: historias continuadas, historias conectadas
Authors: García Mirón Silvia , Legerén Lago Beatriz
Published: April 2019

La convergencia multimedia y creación de sinergias entre distintos medios de comunicación ha supuesto la respuesta en la creación de historias de ficción o el planteamiento de estrategias en la oferta de contenidos —principales o complementarios al eje narrativo—, resultando de interés para aquellos espectadores o usuarios que demandan un tipo de consumo profundizando en tramas y subtramas o en el que puedan ser partícipes e incluso detonadores de la evolución en la narrativa o el devenir de los personajes así como para ofrecer alternativas para sus intereses como fan. En este sentido, la interrelación entre videojuegos y otros medios ha sido desde hace décadas unaconstante con determinados títulos y personajes y en ambas direcciones. De este modo, y observando los videojuegos más vendidos en los últimos dos años, advertimos que las relaciones entre este sector y el medio cinematográfico o televisivo es una realidad que se mantiene a día de hoy. Nos detendremos con la presente investigación, por tanto, en ofrecer una propuesta de las posibles relaciones (interrelaciones) que se producen, en concreto, entre los videojuegos y el medio televisivo, ya sea desde un punto de vista estético y/o visual, técnico, narrativo o de contenido. El diseño de la investigación ofrece un carácter descriptivo y exploratorio con la finalidad de que este texto sirva como punto de partida para profundizar sobre las confluencias entre los videojuegos y otros sectores audiovisuales planteándonos observar a corto y medio plazo nuevas posibilidades de relaciones así como casos significativos de análisis en este sentido.
Patrones de autoridad e influencia en instagram para la gestión de la comunicación organizacional y de las marcas personales
Authors: Sixto García José
Published: April 2019

Con más de 800 millones de usuarios activos al mes Instagram se ha convertido en la red de moda para la distribución de contenido audiovisual, especialmente fotografía y vídeo corto, las denominadas historias. Lapertinencia de la red para la explotación de las marcas personales la demuestran los ejemplos de influencers que han nacido en Instagram y que ahora actúan como prescriptores de otras marcas comerciales. Sin embargo,¿cómo pueden aprovechar las organizaciones esta red para acercarse a los públicos y mejorar los niveles de engagement?En este texto analizamos las posibilidades y los recursos que ofrece Instagram para la gestión de la comunicación en las organizaciones, diferenciando entre las prácticas propias de usuarios particulares y las estrategias orientadas a un tratamiento profesional de la marca. Se presta especial atención a las potencialidades del contenido autodestruible que la red permite materializar a través de las historias para determinar su pertinencia de uso en la planificación de community management. Se describen y analizan los patrones y los modelos de gestión que denotan autoridad e influencia y se examina qué cuentas alcanzan mayor notoriedad en la red. Se concluye valorando los estándares de analítica que se han de considerar para la medición de audiencias, del retorno y de la inversión realizada.
Terrorismo: efeitos dos “new media” na difusão informativa
Authors: Fernandes Brigas Joaquim Manuel , De Sousa Marques Simões Pedro Miguel , Aguiar Engrácio Handerson Webber
Published: April 2019

O terrorismo sempre esteve presente nas sociedades contemporâneas, fazendo, infelizmente, parte do nosso dia-a-dia. Dessa forma, são importantes definições precisas desse fenómeno; suas diferenças e interações sociais; definir as formas de difusão das mensagens, sua interação através dos media, assim como, tentar minimizar os seus efeitos. A sociedade da hipercomunicação em que vivemos atualmente facilita a visibilidade pública, e as ações que os terroristas tentam dinamizar, tem por base a comunicação como chave principal na difusão pública dos seus atos. A alteração dos paradigmas da comunicação, resultantes acima de tudo, de um crescente aumento das capacidades tecnológicas, acessíveis a todos, torna possível a difusão de itens por todo o Mundo, moldando a opinião pública e concedendo uma posição de destaque aos terroristas na gestão da informação e comunicação. O facto de os media atuais trabalharem numa perspetiva “cyber” e através de dispositivos multi-plataformas, permite a concretização de forma maisabrangente e célere os objetivos dos terroristas, conseguindo atingir uma franja de público muito mais atenta aos seus interesses, capazes de interagir de forma muito mais positiva. A análise das reações através das redes sociais por parte das comunidades afetadas pelo terrorismo, pode ser particularmente interessante, assim como das que são suas “oponentes”, como no caso das sociedades cristãs e muçulmanas aquando de atentados terroristas pelos radicais islâmicos na Europa, de que é exemplo o atentado de Londres em março de 2017. Um aspeto que trataremos num estudo de caso de um fórum português.
Two mathematical approaches to study the phosphorus eutrophication of a wetland in Puerto Rico
Authors: Paredes Gutiérrez Marlio , Torres Velasquez Brenda Carolina , Sanchez Colon Yashira Marie , Schaffner Gibbs Fred Charles
Published: April 2019

Introduction: Laguna Cartagena (LC), a wetland in Lajas, Puerto Rico, has been negatively impacted by nutrients, mainly phosphorus run-off from agricultural activities until the end of sugar cane cultivation in the late 1900s.  This led to P concentration remain high at hypereutrophic state that was irremediable even after a 5-fold reduction in source water nutrient concentration.

Objective: The main goal of this research paper is to apply two different mathematical approaches to assess the eutrophication level of a wetland in Puerto Rico.

Method:   Grey Cluster Method (GCM) was used to classify LC’s eutrophic state by applying the International and Chinese trophic standards and two parameters, total phosphorous (TP) and total nitrogen (TN).  Mean TP and TN from LC consolidated bottom substrate and flocculence samples were used to classify LC.  To address whether LC can recover, soluble reactive phosphorus (SRP) and TP from LC inlet, outlet and center water samples were used to model (differential equation) the input and loss of phosphorus in LC and determine whether an equilibrium point exists.  GCM analysis classified LC as a eutrophic wetland using the International standard and hypereutrophic using the Chinese standard.

Results:  Trophic state classification did not vary with use of consolidated bottom substrate versus flocculence samples. The differential equation model showed that SRP and TP levels within LC were higher than levels of SRP and TP entering LC, which could be caused by a nutrient recycling process within LC that may predict failure of remediation efforts.  An equilibrium point was found at the eutrophic level, which means that even if there is a reduction in phosphorus input, there will not be a change in LC’s eutrophic state.

Conclusions: Chinese trophic standard indicated LC was in a hypertrophic state. Similar results were found using the international standard. The differential equation model showed that LC is irreversible.
Feminidades, cuerpo y equipo
Authors: González Sánchez Diana
Published: April 2019

Este artículo se compone de una serie de extracciones de mi tesis de pregrado. El nuevo texto intenta recoger el lado más etnográfico de mi proyecto de grado y a través de este se dispone a mostrar cómo por medio del campo que realicé con el equipo femenino de fútbol de la Universidad Icesi y siendo parte de este, hago un análisis de escenarios como el partido, el entreno y el camerino. Desde aquí muestro la forma en que se dan las relaciones dentro del colectivo, hablo sobre lo que significa integrarse y pertenecer a él. Esta vivencia también me permite explorar lo que significa ser una jugadora de fútbol universitario desde aspectos físicos y emocionales, saber qué se siente, qué duele o aqueja, ver cómo el deporte se refleja en mi cuerpo y concientizar las influencias de él en mi como mujer.
Therapeutic evaluation of efficacy of intralesional bleomycin in common warts including palmo-plantar and periungual warts: a prospective study
Authors: Kumar Prabal , Mehta Karaninder Singh , Mahajan Vikram , Chauhan Pushpinder Singh
Published: April 2019

Background: Commonly used destructive treatment modalities for common warts though effective, are associated with pigmentary changes, scarring and recurrences. Treatment with immune modulators or immunotherapy has shown variable results. We evaluated efficacy and safety of intralesional bleomycin for treating common warts including palmoplantar and periungual warts.

Methods: Two hundred patients with common, palmar, plantar and periungual warts (having 753 warts) were treated with two intralesional injections of bleomycin 1 mg/ml at two weekly intervals. They were followed up at 4weeks and 12 weeks for cure, adverse effects and partial clearance or recurrence.

Results: Only 183 (M: F 95:88) patients having 703 warts completed the study. Overall, complete clearance in 669 (95.16%) warts in 156 (85.2%) patients and partial clearance in 24 (3.4%) warts in 21 (11.4%) patients were observed. Patients with complete/partial clearance were highly satisfied from the treatment. Recurrence was seen in 6 (3.27%) patients. Most patients had injection site pain for 2-3 days not warranting discontinuation of treatment. Other adverse effects included temporary hyperpigmentation in 46, altered skin texture in 12 and injection site infection in 6 patients, respectively.

Conclusions: Intralesional bleomycin appears effective, safe, and acceptable treatment modality for common warts including palmoplantar and periungual warts. It carries the advantage of low dose, insignificant adverse effects and high patient satisfaction. 
Conselhos Escolares para que? Análise de uma Experiência com Gestão Escolar Democrática
Authors: Euzébios Filho Antonio
Published: April 2019

Esse artigo relata a experiência de dois anos de um projeto de extensão com foco no fortalecimento dos Conselhos Escolares, realizado por membros do curso de psicologia de uma universidade do interior do Estado de São Paulo. O projeto aconteceu em três escolas municipais de ensino fundamental, no bojo do Programa municipal de fortalecimento dos Conselhos. Encontrou subsídio teórico em referências da psicologia escolar e da psicologia social, articulados pelo materialismo histórico e dialético. Durante o período de execução do projeto, foram realizadas ações como: encontros de formação com membros dos Conselhos Escolares (professores, funcionários, estudantes e pais), diagnósticos participativos, apoio no processo eleitoral e na elaboração coletiva de planos de trabalho das gestões eleitas, entre outras. Finalmente, intersecionando nossa experiência com o arcabouço teórico concluímos que, apesar dos avanços históricos da gestão escolar democrática e da política de estimulo aos Conselhos no município, foram identificadas barreiras para que essas instâncias não sejam figurativas ou acessórias das direções instituídas das escolas. A superação desse quadro começa pelo questionamento dos limites da própria democracia formal, dentro e fora da escola.
Nurses Between the Hammer and the Anvil: Analyzing the Role of the Workplace Prevention Climate in Reducing Internal and External Violence
Authors: Viotti Sara , Guidetti Gloria , Converso Daniela
Published: April 2019

The aim of this study was to test a model including relationships among internal and external violence, workplace violence-prevention climate, exhaustion, and intention to leave (ITL) in a sample of nurses. Data were collected by a self-report questionnaire involving nurses (n = 313) from two multispecialist hospitals in Italy. The survey was cross-sectional and nonrandomized. Path analyses showed the presence of the mediating role of internal violence between workplace prevention climate and exhaustion, as well as the mediating function of both types of violence between workplace prevention climate and ITL. Moreover, an indirect effect through exhaustion between internal violence and ITL was highlighted. These findings suggested that organizations that invest in preventive measures may reduce incidents of violence and, in turn, prevent negative consequences on worker well-being.
Effects of Poly-Victimization Before Age 18 on Health Outcomes in Young Kenyan Adults: Violence Against Children Survey
Authors: Nguyen Kimberly H. , Kegler Scott R. , Chiang Laura , Kress Howard
Published: April 2019

Children's exposure to poly-victimization, which is the experience of multiple types of victimization, has been found to be associated with negative health outcomes and risk behaviors. We examined the collective effects of childhood sexual, physical, and emotional violence on selected self-reported health outcomes among young Kenyan females and males using the Violence Against Children Survey (VACS). Overall, 76.2% of females and 79.8% of males were victims of sexual, physical, or emotional violence prior to age 18, and one-third (32.9% and 34.5%, respectively) experienced two or more types of violence. Poly-victimization was significantly associated with current feelings of anxiety, depression, and suicidal thoughts in females and males, as well as self-reported fair or poor health in males (p < .05) as compared to those who experienced no violence. The study data demonstrate an urgent need to reduce all types of violence against children, as well develop appropriate strategies for its prevention.
KADAR DEBU SEMEN TERHIRUP MENGGUNAKAN PERSONAL DUST SAMPLER DAN GANGGUAN FAAL PARU PADA OPERATOR UNIT FINISH MILL
Authors: Rachmani Glori Abdiningsih
Published: April 2019

Exposure to dust in the work environment is a potential factor that can cause impaired pulmonary function. Concentration of dust in the air is one factor that affects the severity caused. Higher exposure to dust in the air, increase the risk of impaired pulmonary function. The objective of the research was to analyze the exposure to respirable cement dust and pulmonary function impairment of Finish Mill operators in PT. Semen Indonesia, Tuban Regency. This study used a cross-sectional study design, with the number of sample using purposive sampling method as many as 10 people. The level of inhaled semen dust is measured using a Personal Dust Sampler (PDS). The characteristics of workers are also seen include age, length of employment, smoking habits, use of personal protective equipment and respiratory complaints felt. The results of this study were 90% of operators with respirable dust levels > 3 mg/m3. The highest respirable dust content was 26,7151 mg/m3. The lowest respirable dust content was 1.4665 mg/m3. In addition, 22.2% of operators who have inhaled dust levels > 3 mg/m3 have impaired pulmonary function. Conclusions can be drawn pulmonary function impairment more experienced by operators aged 36 - 45 years, with a working period of more than 15 years. Smoking habits and respiratory history may be seen from operator respiratory complaints.Keywords: finish mill operators, pulmonary function test, respirable cement dust.
ANALISIS RISIKO SIKAP KERJA DENGAN KELUHAN MUSCULOSKELETAL DISORDER PADA PORTER STASIUN SURABAYA GUBENG
Authors: Puspitasari Ervin Putri
Published: April 2019

Musculoskeletal disorders (MSDs) is a type of disorder in the body structure caused or compounded by a unergonomic work attitude. One of jobs at Surabaya Gubeng Station which possible to increase the risk of Musculoskeletal disorders is porter. This study aimed to analyze risk of work attitude with complaint of Musculoskeletal Disorders at Surabaya Gubeng Station’s porter. This study was analytic observational research with cross sectional research design. Data obtained from 60 porters who worked at Surabaya Gubeng Station. Musculoskeletal disorders were obtained from Nordic Body Map (NBM) observation sheet. Characteristics of respondents obtained from interview. Work attitude risk was obtained by Rapid Entire Body Assessment (REBA) method. In this study the independent variable was the risk of work attitude. Dependent variable was a complaint of Musculoskeletal disorders. Data were tested using Cramer Coefficient. The prevalence of MSDs found in this study was 86.7% with low category was counted 96.2% and medium category was 3.8%. Musculoskeletal disorders in the porter occur at night before bed and frequency of Musculoskeletal disorders occurs every 1-2 times/ week. Porter experienced most MSDs complaints on the body at the right shoulder, left shoulder, right calf, and left calf. Cramer coefficient showed a value of 0.197 on risk of right body work attitude and Cramer Coefficient of 0.046 on risk of left body work attitude. The conclusion of this research was the risk of right and left body work attitude was not affect complaint of Musculoskeletal Disorder. Keywords: musculoskeletal disorder, porter, station, risk of work attitude
HUBUNGAN PENERAPAN MUSIK KERJA ISLAMI DENGAN KEJADIAN STRES KERJA DI SAKINAH SUPERMARKET
Authors: Baitur Rozaq Jiana Rofik
Published: April 2019

Job stress is a physical and emotional disturbance as a result of a mismatch between capability, resources or the needs of workers coming from the worker's environment. Job stress is one of the most important issues discussed in the world of health, as some studies found its impacts on workers and productivity. To reduce the incidence of this work stress one of the Health Safety Environment (HSE) program was created. One of the Health Safety Environment (HSE) program which applied by Sakinah Supermarket is Islamic job music. The purpose of this study is to determine the relationship between Islamic music work with the incidence of job stress at Sakinah Supermarket. Quantitative research approach with cross sectional research design. The population in this research consist 68 workers, where research sample counted 40 workers. The variables studied were acceptance of Islamic music work and stressful work events. The data collection instrument used a questionnaire modification of the NIOSH Job Generic Stress Questionnaire. To test the relationship between variables Spearman correlation test used. The result of the research shows that workers' acceptance on Islamic music work in the high category (52.5%) is very high (45%) and the incidence of work stress does not exist where majority of respondents are in light work stress category (72.5%). Based on the Spearman correlation test the relationship between the two significant variables.Keywords: HSE program, islamic job music, job stress
The Meaning of the Microprocessor: Accounting for Evolution of Structural-Functional Novelty in the Canonical microRNA Biogenesis Pathway
Authors: Robinson Jeffrey
Published: April 2019

Subsidiary to detection and assignment of novel microRNAs in non-model taxa, it is standard to identify and compare genomic or transcript sequence of Drosha and Pasha. Detection of both (1) bona fide microRNAs and (2) presence of Drosha/Pasha orthologs is often assumed to represent a functional canonical eumetazoan microRNA biogenesis pathway. However, this is not often experimentally confirmed in non-model taxa, and therefore the assumption is not necessarily valid. Below I describe several lines of evidence for this assertion.
Farmer Awareness to the Dangers of Heavy Metal Cadmium (Cd) Pollution due to Over-Fertilization in Sragen Regency Central Java
Authors: Pradika Visnu , Masykuri Mohammad , Supriyadi Supriyadi
Published: April 2019

P fertilization can add Cd metal content to agricultural land because the raw material for making P fertilizer comes from phosphate rock which naturally contains Cd metal. Farmers assume that by providing fertilizers with high doses can provide maximum results. Community’s knowledge of heavy metals in the environment is still low. This study aims to examine the awareness of farmers in Sragen Regency Central Java to the potential of heavy metal pollution that occurs. This research was conducted from July to December 2017. The type of this research is quantitative descriptive research using a questionnaire with the number of respondents amounting to 10% of the number of farmers, namely 30 farmers. The results show that about 61.11% of the community doesn’t understand that the presence of heavy metals in the environment can cause many problems. About 60% of the community doesn’t understand that the inorganic fertilizers commonly used by them contain heavy metals (especially Cd metal). People unaware of heavy metal pollution due to over-fertilization is 65.01%. Although the community's knowledge and awareness of heavy metals are still low, the community awareness about environmentally friendly agriculture is high (61.33%). About 53.34% of the community doesn’t know that their behavior in using inorganic fertilizers in the long term will increase the accumulation of Cd metal in agricultural land and rice plant tissue. About 70% of the community doesn’t know that agricultural land that is used continuously to plant (without interspersed with non-paddy crops) will cause land degradation.
The Analysis of the Learning Efficiency of Bidikmisi Students
Authors: Kuswanto Kuswanto
Published: April 2019

This study aims to determine the factors that influence student learning outcomes and the level of efficiency of the use of these inputs. Respondents in this study were the recipients of the 2015 - 2017 Bidikmisi class at the PIPS Department of the University of Jambi FKIP, namely 53 people. This study uses quantitative methods. Data were analyzed using the Stochastic frontier production function approach. The results showed that, first the use of books / modules had a positive and significant effect on the learning output of bidikmisi recipient students. Second the use of material photocopy material has a positive and significant effect on learning output. And, third, the use of pulses for internet access has a positive and significant effect. The level of student learning efficiency in using learning inputs averaged 94 percent. Student learning inefficiency is influenced by organizational activities and interaction with Bidikmisi managers, significant at Î± = 5 percent.
Marketing Mix-7Ps: The Effect on Customer Satisfaction
Authors: Saidani Basrah , R Sudiarditha I Ketut
Published: April 2019

Business competition is getting tougher making the marketing mix used as a tool for tactical marketing tools that can be controlled to produce the desired response in the target market. This study aims to determine the magnitude of the influence of marketing mix-7Ps on consumer satisfaction for the elderly in the Special Capital Region of Jakarta. The research method uses a survey with a questionnaire as a data collection tool. Samples were taken using simple random sampling technique produced 70 respondents. Data is processed using multiple regression analysis techniques. The results of the study show that: (1) empirically proven products, prices, distributions, promotions, and processes have a significant influence on customer satisfaction; meaning that the better the product, price, distribution, promotion and process, the more customer satisfaction increases. (2) Empirically proven physical facilities and people do not affect consumer satisfaction; meaning that physical facilities and people do not significantly result in customer satisfaction. Thus the findings of this study prove that physical facilities and people are not the main ones in consuming a product, but the most important thing is the quality of the product itself which can be used according to its function.
The Diagnostic Accuracy of an Intelligent and Automated Fundus Disease Image Assessment System with Lesion Quantitative Function (SmartEye) in Diabetic Patients
Authors: XU Yi , WANG Yongyi , LIU Bin , TANG Lin , LV Liangqing , LU Lina , KE Xin , LING Saiguang , ZOU Haidong
Published: April 2019

Background

With the diabetes mellitus (DM) prevalence increasing annually, the human grading of retinal images to evaluate DR has posed a substantial burden worldwide. SmartEye is a recently developed fundus image processing and analysis system with lesion quantification function for DR screening. It is sensitive to the lesion area and can automatically identify the lesion position and size. We reported the diabetic retinopathy (DR) grading results of SmartEye versus ophthalmologists in analyzing images captured with non-mydriatic fundus cameras in community healthcare centers, as well as DR lesion quantitative analysis results on different disease stages.

Methods

This is a cross-sectional study. All the fundus images were collected from the Shanghai Diabetic Eye Study in Diabetics (SDES) program from Apr 2016 to Aug 2017. 19904 fundus images were acquired from 6013 diabetic patients. The grading results of ophthalmologists and SmartEye are compared. Lesion quantification of several images at different DR stages is also presented.

Results

The sensitivity for diagnosing no DR, mild NPDR (non-proliferative diabetic retinopathy), moderate NPDR, severe NPDR, PDR (proliferative diabetic retinopathy) are 86.19%, 83.18%, 88.64%, 89.59%, and 85.02%. The specificity are 63.07%, 70.96%, 64.16%, 70.38%, and 74.79%, respectively. The AUC are PDR, 0.80 (0.79, 0.81); severe NPDR, 0.80 (0.79, 0.80); moderate NPDR, 0.77 (0.76, 0.77); and mild NPDR, 0.78 (0.77, 0.79). Lesion quantification results showed that the total hemorrhage area, maximum hemorrhage area, total exudation area, and maximum exudation area increase with DR severity.

Conclusions

SmartEye has a high diagnostic accuracy in DR screening program using non-mydriatic fundus cameras. SmartEye quantitative analysis may be an innovative and promising method of DR diagnosis and grading.
Improving Perception and Confidence Toward Bystander Cardiopulmonary Resuscitation and Public Access Automated External Defibrillator Program: How Does Training Program Help?
Authors: Liaw Siew Yee , Chew Keng Sheng , Zahedi Ahmad Zulkarnain Ahmad , Wong Shirly Siew Ling , Singmamae Nariman , Kaushal Dev Nath , Chan Hiang Chuan
Published: April 2019

Background: In conjunction with an automated external defibrillator (AED) placement program at various locations within a public university in Malaysia, a series of structured training programs were conducted. The objectives of this study is to (1) evaluate the effectiveness of a structured training program in improving the perception of the importance of AED and CPR (2) evaluate the confidence of the employees in using an AED and performing bystander CPR (3) identify the fears and concerns of these employees in using AED and performing CPR (4) determine the perception of these employees towards the strategy of the AEDs placed at various locations within the university.
Methods: In this single center observational study, a validated questionnaire aimed to assess the university employees' attitude and confidence in handling AED and performing CPR before (pre-test) and immediately after (post-test) the training program was conducted.
Results: A total of 184 participants participated om this study. Using Wilcoxon signed-rank test, the training programs appeared to have improved the perception that “using AED is important for unresponsive victims” (z = 4.32, p<0.001) and that “AED practice drills should be performed on a regular basis” (z = -2.41, p = 0.02) as well as increased the confidence to perform CPR (z = -8.56, p<0.001), use AED (z = -8.93, p<0.001), identify victims with no signs of life (z = -7.88, p<0.001) and the willingness to perform CPR and AED without hesitancy (z = -8.91, p<0.001). Fears and concerns on performing CPR and using AED also appeared to have been significantly reduced and the perception on placement strategies of these AEDs were generally positive.
Conclusion: Using the theory of planned behavior as the explanatory framework, training programs appears to be helpful in improving the perception and the confidence of the participants towards performing CPR and using AED through the promotion of positive attitude, positive societal expectation and a positive sense of empowerment. But whether this positive effect will translate into actual CPR performance and AED application in a real cardiac arrest is yet to be seen.
Cytomegalovirus Seroprevalence and Titres in Solid Organ Transplant Recipients and Non-transplant Individuals in Seoul, South Korea
Authors: La Yeonju , Kwon Da Eun , Yoo Seul Gi , Lee Kyoung Hwa , Han Sang Hoon , Song Young Goo
Published: April 2019

Background: Cytomegalovirus (CMV) can cause poor outcomes in solid organ transplant (SOT) recipients and have relation to cardiovascular diseases (CVD) in general population. The anti-CMV immunoglobulin G (IgG) seroepidemiology is useful for identifying the risk of post-SOT CMV infection or disease as well as immunosenescence or CVD. However, recent CMV seroprevalence and titre have not been fully evaluated with respect to age distribution and comparison between SOT recipients and non-transplant individuals.
Methods: We retrospectively retrieved all anti-CMV IgG results from 12658 individuals aged of > one years screened between July 2006 and Nov. 2017 at the Severance Hospital at Seoul. The cohort excluding hematopoietic stem cell transplant recipients and subjects with equivocal values included 2184 SOT recipients and 9738 non-transplant individuals. All IgG results in SOT recipients were measured at pre-transplant period, and only first values among subjects with repeated tests were included in the analyses.
Results: The overall IgG seroprevalence and titres were significantly higher among SOT recipients relative to non-transplant individuals (98.7% vs. 94.8%, p < 0.001 and 64.7 ± 44.3 vs. 54.7 ± 38.9 arbitrary units [aU]/mL, p < 0.001, respectively). The lowest seropositive rates were observed among both SOT recipients and non-transplant individuals aged 11–15 years (70.6% and 70.2%, respectively). The frequency of seropositivity among adults aged ≥ 41 years increased to ≥ 99% in both groups. Age and SOT group were independently associated factors with higher CMV seroprevalence (OR, 1.12, 95% CI, 1.11-1.12, p < 0.001 and OR 2.43, 95% CI, 1.65-3.59, p < 0.001, respectively). Although liver (99.7%, 80.1 ± 54.5 aU/mL) and lung (100%, 84.3 ± 68.3 aU/mL) transplants had significantly higher seropositive rates and titres compared to kidney (98.3%, 59.4 ± 36.1 aU/mL) and heart (97.0%, 58.1 ± 46.9 aU/mL) transplant (overall p = 0.024 and < 0.001, respectively), the different transplant organs did not affect the seroprevalence in multivariate regression analysis.
Conclusions: CMV seropositivity was lowest among school-aged children. IgG testing revealed that most adult SOT recipients in South Korea faced an intermediate serostatus risk of post-transplant CMV infection and disease.
Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to differences in gene expression
Authors: Reimer Michael J , Pulakanti Kirthi , Shi Linzheng , Abel Alex , Liang Mingyu , Malarkannan Subramaniam , Rao Sridhar
Published: April 2019

Background: The Tet protein family (Tet1, Tet2, and Tet3) regulate DNA methylation through conversion of 5-methylcytosine to 5-hydroxymethylcytosine which can ultimately result in DNA demethylation and play a critical role during early mammalian development and pluripotency¬. While multiple groups have generated knockouts combining loss of different Tet proteins in murine embryonic stem cells (ESCs), differences in genetic background and approaches has made it difficult to directly compare results and discern the direct mechanism by which Tet proteins regulate the transcriptome. To address this concern, we utilized genomic editing in an isogenic pluripotent background which permitted a quantitative, flow-cytometry based measurement of pluripotency in combination with genome-wide assessment of gene expression and DNA methylation changes. Our ultimate goal was to generate a resource of large-scale datasets to permit hypothesis-generating experiments.
Results: We demonstrate a quantitative disparity in the differentiation ability among Tet protein deletions, with Tet2 single knockout exhibiting the most severe defect, while loss of Tet1 ¬alone or combinations of Tet genes showed a quantitatively intermediate phenotype. Using a combination of transcriptomic and epigenomic approaches we demonstrate an increase in DNA hypermethylation and a divergence of transcriptional profiles in pluripotency among Tet deletions, with loss of Tet2 having the most profound effect in undifferentiated ESCs.
Conclusions: We conclude that loss of Tet2 has the most dramatic effect both on the phenotype of ESCs and the transcriptome compared to other genotypes. While loss of Tet proteins increased DNA hypermethylation, especially in gene promoters, these changes in DNA methylation did not correlate with gene expression changes. Thus, while loss of different Tet proteins alters DNA methylation, this change does not appear to be directly responsible for transcriptome changes. Thus, loss of Tet proteins likely regulates the transcriptome epigenetically both through altering 5mC but also through additional mechanisms. Nonetheless, the transcriptome changes in pluripotent Tet2-/- ESCs compared to wild-type implies that the disparities in differentiation can be partially attributed to baseline alterations in gene expression.
Resistant Pepper Carrying N, Me1, and Me3 have Different Effects on Penetration and Reproduction of Four Major Meloidogyne species
Authors: Hajihassani Abolfazl , Rutter William B. , Luo Xuelin
Published: April 2019

Root-knot nematode (Meloidogyne spp.) exhibits a substantial problem in pepper production, causing reduction in yield throughout the world. Continued assessment for root-knot resistance is important for developing new resistance cultivars. In this study, the effect of Me and N genes on the penetration and reproduction of M. incognita race 3, M. arenaria race 1, M. javanica, and M. haplanaria was examined under controlled greenhouse conditions using susceptible and resistant pepper lines/cultivars (Mellow Star, Yolo Wonder B, Charleston Belle, HDA-149, HDA-330, PM-217, and PM-687) differing in the presence or absence of resistant genes. The penetration and resistance responses of these pepper lines differed depending on the nematode species. More second-stage juveniles penetrated roots of susceptible control cultivar Mellow Star than roots of resistant cultivars/lines. Although, there was no significant difference in the nematode penetration among resistant lines 1 and 3 days after inoculation (DAI), variability in the penetration of M. incognita, M. javanica, and M. haplanaria was observed 5 DAI. This demonstrates the variability among different nematode resistance genes to invasion by Meloidogyne spp. Based on nematode gall index (GI) and reproduction factor (RF), Charleston Belle, HDA-149, PM-217 and PM-687 showed very high resistance (GI < 1 and RF < 0.1) to M. incognita, M. arenaria, and M. javanica. Although, all the Meloidogyne-resistant pepper lines evaluated were resistant to M. javanica and M. haplanaria, the susceptible cultivar Mellow Star was a good host for all nematode species having an RF ranging from 8.1 to 34.7. The N, Me1, and Me3 genes controlled resistance to reproduction of all species of Meloidogyne examined.
The quench control of water estimates in convergent margin magmas
Authors: Gavrilenko Maxim , Krawczynski Michael , Ruprecht Philipp , Li Wenlu , Catalano Jeffrey G.
Published: April 2019

Here we present a study on the quenchability of hydrous mafic melts. We show via hydrothermal experiments that the ability to quench a mafic hydrous melt to a homogeneous glass at cooling rates relevant to natural samples has a limit of no more than 9 ± 1 wt% of dissolved H2O in the melt. We performed supra-liquidus experiments on a mafic starting composition at 1–1.5 GPa spanning H2O-undersaturated to H2O-saturated conditions (from ~1 to ~21 wt%). After dissolving H2O and equilibrating, the hydrous mafic melt experiments were quenched. Quenching rates of 20 to 90 K/s at the glass transition temperature were achieved, and some experiments were allowed to decompress from thermal contraction while others were held at an isobaric condition during quench. We found that quenching of a hydrous melt to a homogeneous glass at quench rates comparable to natural conditions is possible at water contents up to 6 wt%. Melts containing 6–9 wt% of H2O are partially quenched to a glass, and always contain significant fractions of quench crystals and glass alteration/devitrification products. Experiments with water contents greater than 9 wt% have no optically clear glass after quench and result in fine-grained mixtures of alteration/devitrification products (minerals and amorphous materials). Our limit of 9 ± 1 wt% agrees well with the maximum of dissolved H2O contents found in natural glassy melt inclusions (8.5 wt% H2O). Other techniques for estimating pre-eruptive dissolved H2O content using petrologic and geochemical modeling have been used to argue that some arc magmas are as hydrous as 16 wt% H2O. Thus, our results raise the question of whether the observed record of glassy melt inclusions has an upper limit that is partially controlled by the quenching process. This potentially leads to underestimating the maximum amount of H2O recycled at arcs when results from glassy melt inclusions are predominantly used to estimate water fluxes from the mantle.
Effect of bubble characteristics and nozzle size on the membrane distillation enhanced by gas–liquid two-phase flow
Authors: Zhang Dashuai , Zhang Xiaopeng , Chen Li , Lili Wang , Di Wu , Xiong Yuqin , Lin Qiang , Shi Zaifeng
Published: April 2019

This study investigates the membrane performance and fouling control in bubble-assisted sweeping gas membrane distillation with high concentration saline (333 K saturated solution) as feed. The results show that a longer bubbling interval (3 min) at a fixed bubbling duration of 30 s can most efficiently increase the flux enhancement ratio up to 1.518. Next, the flux increases with the gas flow rate under a relatively lower level, but tends to plateau after the threshold level (1.2 L·min−1). Compared to the non-bubbling case, the permeate flux reaches up to 1.623-fold at a higher bubble relative humidity of 80%. It was also found that greater flux enhancement can be achieved and, meanwhile, dramatic flux decline can be delayed for an intermittent bubbling system with a smaller nozzle size. These results accord well with the observations of fouling deposition in situ on the membrane surface with scanning electron microscope (SEM).
Kurds HLA Genes: Its Implications in Transplantation and Pharmacogenomics
Authors: Amirzargar Ali , Rey Diego , Muñiz Ester , Palacio-Grüber Jose , Nikbin Behrouz , Nicknam Hosein , Khosravi Farideh , Joshghan Hamidreza , Areces Cristina , Enríquez-de-Salamanca Mercedes , Martinez-Quiles Narcisa , Martín-Villa José Manuel , Arnaiz-Villena Antonio
Published: April 2019

HLA genes (class I and II) have been studied in a Kurd population from Iran (North West towns of Saqqez and Baneh, close to Irak border). Kurds speak an Iranian language. HLA Kurd profile has been compared with those of Central Asians, Siberians, Mediterraneans and other worldwide populations; a total of 7746 chromosomes were used for computer comparisons. Both Neighbor-joining and correspondence genetic analyses place Kurds in the Mediterranean population cluster, close to Iranians, Europeans and Caucasus populations (Svan and Georgian). New extended HLA haplotypes are described, being A*02:01-B*35:01-DRB1*01:01-DQB1*05:01 and A*24:02-B*18:09-DRB1*11:01- DQB1*03:01 the most frequent ones; other Kurd extended haplotypes are also found in Azeris and Palestinians. This research work may be useful for: 1) future Iranian Kurds transplantation regional programs, 2) HLA pharmacogenomics in order to practise a preventive Medicine and drug side effects, and 3) Epidemiology of HLA-associated diseases in Kurds.
Molecular Identification of Mycobacterium Species of Public Health Importance in Cattle in Zimbabwe by 16S rRNA Gene Sequencing
Authors: Padya Leah , Chin'ombe Nyasha , Magwenzi Marcelyn , Mbanga Joshua , Ruhanya Vurayai , Nziramasanga Pasipanodya
Published: April 2019

Mycobacteriumspecies are naturally found in the environment as well as in domestic animals such as cattle. So far, more than 150 species ofMycobacterium, some of which are pathogenic, have been identified. Laboratory isolation, detection and identification ofMycobacteriumspecies are therefore critical if human and animal infections are to be controlled. The objective of this study was to identifyMycobacteriumspecies isolated in cattle in Zimbabwe using 16S ribosomal RNA gene amplification and sequencing. A total of 134 cow dung samples were collected throughout Zimbabwe and mycobacteria were isolated by culture. Only 49 culture isolates that were found to be acid-fast bacilli positive by Ziehl-Neelsen staining. The 16S rRNA gene was successfully amplified by PCR in 41 (84%) of the samples. There was no amplification in 8 (16%) of the samples. Out of the 41 samples that showed amplification, 26 (63%) had strong PCR bands and were selected for DNA sequencing. Analysis of the DNA sequences showed that 7 (27%) belonged toMycobacterium neoaurum, 6 (23%) belonged toMycobacterium fortuitum, 3 (12%) toMycobacterium goodii, 2 (1%) toMycobacterium arupense, 2 (1%) toMycobacterium peregrinumorM. septicumand 1 isolate (0.04%) toMycobacterium elephantis. There were 5 (19%) isolates that were non-mycobacteria and identified as Gordonia terrae, a close relative ofMycobacterium. The study therefore provided a molecular basis for detection and identification ofMycobacteriumspecies in animals and humans.