bluuebunny/crossref_metadata_2025 huggingface dataset:
Lipophilicity and ADMET Analysis of Quinoline-1,4-quinone Hybrids
Authors: Kadela-Tomanek Monika , Jastrzębska Maria , Chrobak Elwira , Bębenek Ewa
Published: December 2022

Lipophilicity is one of the basic properties of a potential drug determining its solubility in non-polar solvents and, consequently, its ability to passively penetrate the cell membrane, as well as the occurrence of various pharmacokinetic processes, including adsorption, distribution, metabolism, excretion, and toxicity (ADMET). Heterocyclic compounds containing a nitrogen atom play a significant role in the search for new drugs. In this study, lipophilicity as well as other physicochemical, pharmacokinetic and toxicity properties affecting the bioavailability of the quinolone-1,4-quinone hybrids are presented. Lipophilicity was determined experimentally as well as theoretically using various computer programs. The tested compounds showed low values of experimental lipophilicity and its relationship with the type of 1,4-quinone moiety. Introduction of the nitrogen atom reduced the lipophilicity depending on the position at the 5,8-quinolinedione moiety. The bioavailability of the tested compounds was determined in silico using the ADMET parameters. The obtained parameters showed that most of the hybrids can be used orally and do not exhibit neurotoxic effects. Similarity analysis was used to examine the relationship between the ADMET parameters and experimental lipophilicity. The ability of hybrids to interact with biological targets was characterized by global reactivity descriptors. The molecular docking study showed that the hybrids can inhibit the BCL-2 protein.
BFSS Matrix Model Cosmology: Progress and Challenges
Authors: Brahma Suddhasattwa , Brandenberger Robert , Laliberte Samuel
Published: December 2022

We review a proposal to obtain an emergent metric space-time and an emergent early universe cosmology from the Banks–Fischler–Shenker–Susskind (BFSS) matrix model. Some challenges and directions for future research are outlined.
Assessing Asymmetry in Exercise Intensity Domains between Lower Limbs in Persons with Multiple Sclerosis: A Pilot Study
Authors: Farrell John W. , Shipman Shelby , D. Black Christopher , Ade Carl J. , Larson Rebecca D.
Published: December 2022

Persons with multiple sclerosis (PwMS) experience a variety of physical impairments that can present in an asymmetrical pattern, resulting in significant differences between contralateral limbs (i.e., >10%). Asymmetries in PwMS have been associated with walking impairment and postural instability. Exercise intensity has been shown to influence the degree of asymmetry outcomes in healthy populations, and may have an impact on appropriate exercise prescriptions. The purpose of the current pilot study was to investigate the potential presence of asymmetry in metabolic events demarcating exercise intensity domains during single-leg cycling in PwMS. Five PwMS (Expanded Disability Status Scale range 2.0 to 4.5) completed a single leg incremental cycling test (SLICT) and a series of single-leg constant power time-to-exhaustion trials to determine gas exchange threshold (GET), peak oxygen consumption (VO2peak), peak power output (PPO), critical power (CP), and W’ (exercise tolerance above CP) for both lower limbs. Statistical analysis revealed no significant between-limb differences for VO2peak, GET, CP, PPO, and W’. Only W’ asymmetry score was significantly (49.5 ± 28.7 vs. 10.0, p = 0.04) greater than 10%. No significant differences between asymmetry scores at the GET, CP, and PPO were observed. Results from the current pilot investigation suggest that exercise intensity may not influence asymmetry outcomes in PwMS. Future studies with larger sample sizes and those with higher disability levels are required to fully understand the influence of exercise intensity on asymmetry in PwMS.
Assessing Heat Tolerance in Creeping Bentgrass Lines Based on Physiological Responses
Authors: Fan Qianqian , Jespersen David
Published: December 2022

Heat stress is a major concern for the growth of cool-season creeping bentgrass (Agrostis stolonifera L.). Nonetheless, there is a lack in a clear and systematic understanding of thermotolerance mechanisms for this species. This study aimed to assess heat tolerance in experimental lines and cultivars to determine important physiological and biochemical traits responsible for improved tolerance, including the use of OJIP fluorescence. Ten creeping bentgrass lines were exposed to either control (20/15 °C day/night) or high temperature (38/33 °C day/night) conditions for 35 d via growth chambers at Griffin, GA. Principal component analysis and clustering analysis were performed to rank stress performance and divide lines into different groups according to their tolerance similarities, respectively. At the end of the trial, S11 729-10 and BTC032 were in the most thermotolerant group, followed by a group containing BTC011, AU Victory and Penncross. Crenshaw belonged to the most heat-sensitive group while S11 675-02 and Pure Eclipse were in the second most heat-sensitive group. The exceptional thermotolerance in S11 729-10 and BTC032 was associated with their abilities to maintain cell membrane stability and protein metabolism, plus minimize oxidative damages. Additionally, among various light-harvesting steps, energy trapping, dissipation and electron transport from QA to PQ were more heat-sensitive than electron transport from QA to final PSI acceptors. Along with the strong correlations between multiple OJIP parameters and other traits, it reveals that OJIP fluorescence could be a valuable tool for dissection of photosynthetic processes and identification of the critical steps responsible for photosynthetic declines, enabling a more targeted heat-stress screening. Our results indicated that variability in the level of heat tolerance and associated mechanisms in creeping bentgrass germplasm could be utilized to develop new cultivars with improved thermotolerance.
A New Benzothiadiazole Derivative with Systemic Acquired Resistance Activity in the Protection of Zucchini (Cucurbita pepo convar. giromontiina) against Viral and Fungal Pathogens
Authors: Spychalski Maciej , Kukawka Rafal , Prasad Raghavendra , Borodynko-Filas Natasza , Stępniewska-Jarosz Sylwia , Turczański Krzysztof , Smiglak Marcin
Published: December 2022

The ability of plant resistance inducers to provide protection against viral diseases is one of their main advantages over conventional pesticides. In the case of viral diseases that cannot be controlled directly with pesticides, insecticides are used to control the vectors of viruses. However, the effectiveness of such treatments is strictly dependent on the time of application. The plant response to the application of systemic acquired resistance (SAR) inducers, as a result of the stimulating action of these substances, does not depend on the time of application as it triggers the plant’s natural defence mechanism. The best-recognised substance showing SAR inducer activity is acibenzolar-S-methyl ester (ASM, BTH). As its activity against different plant pathogens of crops has been well documented, the current research is concentrated on the search for novel substances of the type. The tested substance, N-methoxy-N-methylbenzo(1,2,3)thiadiazole-7-carboxamide (BTHWA), is an amide derivative of benzothiadiazole, showing plant resistance-inducing activity. This article presents the activity of BTHWA that has led to increased resistance of zucchini (Cucurbita pepo convar. giromontiina) towards viral infections. In addition, since the occurrence of the fungal pathogen, powdery mildew, was also observed during the two-year field experiments, the activity of BTHWA related to the reduction of infection with this fungus was also investigated. The substance was applied in two different variants either four or eight times, over the whole vegetation season. Surprisingly, the variant of four applications performed at the beginning of the vegetation season proved more effective in protection against viruses and fungus. A possible explanation may be the occurrence of the growth–immunity trade-off phenomenon that is known in the literature. Disturbance in plant metabolism resulting from eight applications may lead to lower yields of plants treated with SAR inducers. Perhaps such overstimulation of the plants we treated eight times may not have brought the optimum increase in plant resistance.
Selenium Regulates Antioxidant, Photosynthesis, and Cell Permeability in Plants under Various Abiotic Stresses: A Review
Authors: Liu Haodong , Xiao Chunmei , Qiu Tianci , Deng Jie , Cheng Hua , Cong Xin , Cheng Shuiyuan , Rao Shen , Zhang Yue
Published: December 2022

Plant growth is affected by various abiotic stresses, including water, temperature, light, salt, and heavy metals. Selenium (Se) is not an essential nutrient for plants but plays important roles in alleviating the abiotic stresses suffered by plants. This article summarizes the Se uptake and metabolic processes in plants and the functions of Se in response to water, temperature, light, salt, and heavy metal stresses in plants. Se promotes the uptake of beneficial substances, maintains the stability of plasma membranes, and enhances the activity of various antioxidant enzymes, thus alleviating adverse effects in plants under abiotic stresses. Future research directions on the relationship between Se and abiotic stresses in plants are proposed. This article will further deepen our understanding of the relationship between Se and plants.
Multiomic Approaches Reveal Hormonal Modulation and Nitrogen Uptake and Assimilation in the Initial Growth of Maize Inoculated with Herbaspirillum seropedicae
Authors: Irineu Luiz Eduardo Souza da Silva , Soares Cleiton de Paula , Soares Tatiane Sanches , Almeida Felipe Astolpho de , Almeida-Silva Fabrício , Gazara Rajesh Kumar , Meneses Carlos Henrique Salvino Gadelha , Canellas Luciano Pasqualoto , Silveira Vanildo , Venancio Thiago Motta , Olivares Fabio Lopes
Published: December 2022

Herbaspirillum seropedicae is an endophytic bacterium that can fix nitrogen and synthesize phytohormones, which can lead to a plant growth-promoting effect when used as a microbial inoculant. Studies focused on mechanisms of action are crucial for a better understanding of the bacteria-plant interaction and optimization of plant growth-promoting response. This work aims to understand the underlined mechanisms responsible for the early stimulatory growth effects of H. seropedicae inoculation in maize. To perform these studies, we combined transcriptomic and proteomic approaches with physiological analysis. The results obtained eight days after inoculation (d.a.i) showed increased root biomass (233 and 253%) and shoot biomass (249 and 264%), respectively, for the fresh and dry mass of maize-inoculated seedlings and increased green content and development. Omics data analysis, before a positive biostimulation phenotype (5 d.a.i.) revealed that inoculation increases N-uptake and N-assimilation machinery through differentially expressed nitrate transporters and amino acid pathways, as well carbon/nitrogen metabolism integration by the tricarboxylic acid cycle and the polyamine pathway. Additionally, phytohormone levels of root and shoot tissues increased in bacterium-inoculated-maize plants, leading to feedback regulation by the ubiquitin-proteasome system. The early biostimulatory effect of H. seropedicae partially results from hormonal modulation coupled with efficient nutrient uptake-assimilation and a boost in primary anabolic metabolism of carbon–nitrogen integrative pathways.
Mining Sources of Resistance to Durum Leaf Rust among Tetraploid Wheat Accessions from CIMMYT’s Germplasm Bank
Authors: Huerta-Espino Julio , Singh Ravi P. , Villaseñor-Mir Héctor Eduardo , Ammar Karim
Published: December 2022

A collection of 482 tetraploid wheat accessions from the CIMMYT Germplasm Bank was screened in the greenhouse for resistance to leaf rust disease caused by the fungus Puccinia triticina E. The accessions were screened against two races CBG/BP and BBG/BP in the field at two locations: against race CBG/BP at the Norman E. Borlaug Experimental Station (CENEB) located in the Yaqui Valley in the northern state of Sonora in Mexico during the 2014–2015 growing season; and against race BBG/BP at CIMMYT headquarters in El Batan, Texcoco, in the state of Mexico in the summer of 2015. Among the accessions, 79 durum genotypes were identified, of which 68 continued demonstrating their resistance in the field (past the seedling stage) against the two leaf rust races. An additional set of 41 genotypes was susceptible at the seedling stage, but adult plant race-specific resistance was identified in the field. The 79 seedling-resistant genotypes were tested against 15 different leaf rust races at the seedling stage to measure the usefulness of their resistance in a breeding program. Among the 79 accessions tested, 35 were resistant to all races used in the tests. Two sample sources, CIMMYT (18/35) pre-breeding germplasm and Ethiopian landraces (17/35), showed seedling resistance to all races tested except for seven landraces from Ethiopia, which became susceptible to the Cirno race identified in 2017.
Water and Nitrogen Coupling Increased the Water-Nitrogen Use Efficiency of Oilseed Flax
Authors: Cui Zhengjun , Effah Zechariah , Yan Bin , Gao Yuhong , Wu Bing , Wang Yifan , Xu Peng , Wang Haidi , Zhao Bangqing , Wang Yingze
Published: December 2022

Increasing water shortages and environmental pollution from excess chemical nitrogen fertilizer use necessitate the development of irrigation-nitrogen conservation technology in oilseed flax production. Therefore, a two-year split-plot design experiment (2017–2018) was conducted with three types of irrigation (I) levels (no irrigation (I0), irrigation of 1200 m3 ha−1 (I1200), and 1800 m3 ha−1 (I1800)) as the main plot and three nitrogen (N) application rates (0 (N0), 60 (N60) and 120 (N120) kg N ha−1) as the subplot in Northwest China to determine the effects of irrigation and N rates on oilseed flax grain yield, yield components, water-use efficiency (WUE), and N partial factor productivity (NPFP). The results show that I1800 optimized the farmland water storage and water storage efficiency (WSE), which gave rise to greater above-ground biomass. Under I1800, the effective capsule (EC) number increased significantly with increasing irrigation amounts, which increased significantly with increasing nitrogen application rate (0–120 kg ha−1). Both irrigation and nitrogen indirectly affect GY by affecting EC; the highest grain yield was observed at the I1800N60 treatment, which increased by 69.04% and 22.80% in 2017 and 2018 compared with the I0N0 treatment, respectively. As a result, both irrigation and N affect grain yield by affecting soil water status, improving above-ground biomass, and finally affecting yield components. In addition, I1800N60 also obtained a higher WUE and the highest NPFP due to a higher grain yield and a lower N application rate. Hence, our study recommends that irrigation with 1800 m3 ha−1 coupled with 60 kg N ha−1 could be a promising strategy for synergistically improving oilseed flax WUE, grain yield and yield components within this semi-arid region.
Machine Learning-Based Crop Stress Detection in Greenhouses
Authors: Elvanidi Angeliki , Katsoulas Nikolaos
Published: December 2022

Greenhouse climate control systems are usually based on greenhouse microclimate settings to exert any control. However, to save energy, water and nutrients, additional parameters related to crop performance and physiology will have to be considered. In addition, detecting crop stress before it is clearly visible by naked eye is an advantage that could aid in microclimate control. In this study, a Machine Learning (ML) model which takes into account microclimate and crop physiological data to detect different types of crop stress was developed and tested. For this purpose, a multi-sensor platform was used to record tomato plant physiological characteristics under different fertigation and air temperature conditions. The innovation of the current model lies in the integration of photosynthesis rate (Ps) values estimated by means of remote sensing using a photochemical reflectance index (PRI). Through this process, the time-series Ps data were combined with crop leaf temperature and microclimate data by means of the ML model. Two different algorithms were evaluated: Gradient Boosting (GB) and MultiLayer perceptron (MLP). Two runs with different structures took place for each algorithm. In RUN 1, there were more feature inputs than the outputs to build a model with high predictive accuracy. However, in order to simplify the process and develop a user-friendly approach, a second, different run was carried out. Thus, in RUN 2, the inputs were fewer than the outputs, and that is why the performance of the model in this case was lower than in the case of RUN 1. Particularly, MLP showed 91% and 83% accuracy in the training sample, and 89% and 82% in testing sample, for RUNs 1 and 2, respectively. GB showed 100% accuracy in the training sample for both runs, and 91% and 83% in testing sample in RUN 1 and RUN 2, respectively. To improve the accuracy of RUN 2, a larger database is required. Both models, however, could easily be incorporated into existing greenhouse climate monitoring and control systems, replacing human experience in detecting greenhouse crop stress conditions.
How Temperatures May Affect the Synthesis of Fatty Acids during Olive Fruit Ripening: Genes at Work in the Field
Authors: Contreras Cibeles , Pierantozzi Pierluigi , Maestri Damián , Tivani Martín , Searles Peter , Brizuela Magdalena , Fernández Fabricio , Toro Alejandro , Puertas Carlos , Trentacoste Eduardo R. , Kiessling Juan , Mariotti Roberto , Baldoni Luciana , Mousavi Soraya , Fernandez Paula , Moschen Sebastián , Torres Mariela
Published: December 2022

A major concern for olive cultivation in many extra-Mediterranean regions is the adaptation of recently introduced cultivars to environmental conditions different from those prevailing in the original area, such as the Mediterranean basin. Some of these cultivars can easily adapt their physiological and biochemical parameters in new agro-environments, whereas others show unbalanced values of oleic acid content. The objective of this study was to evaluate the effects of the thermal regime during oil synthesis on the expression of fatty acid desaturase genes and on the unsaturated fatty acid contents at the field level. Two cultivars (Arbequina and Coratina) were included in the analysis over a wide latitudinal gradient in Argentina. The results suggest that the thermal regime exerts a regulatory effect at the transcriptional level on both OeSAD2 and OeFAD2-2 genes and that this regulation is cultivar-dependent. It was also observed that the accumulated thermal time affects gene expression and the contents of oleic and linoleic acids in cv. Arbequina more than in Coratina. The fatty acid composition of cv. Arbequina is more influenced by the temperature regime than Coratina, suggesting its greater plasticity. Overall, findings from this study may drive future strategies for olive spreading towards areas with different or extreme thermal regimes serve as guidance for the evaluation olive varietal patrimony.
Encapsulation with Natural Polymers to Improve the Properties of Biostimulants in Agriculture
Authors: Jíménez-Arias David , Morales-Sierra Sarai , Silva Patrícia , Carrêlo Henrique , Gonçalves Adriana , Ganança José Filipe Teixeira , Nunes Nuno , Gouveia Carla S. S. , Alves Sónia , Borges João Paulo , Pinheiro de Carvalho Miguel Â. A.
Published: December 2022

Encapsulation in agriculture today is practically focused on agrochemicals such as pesticides, herbicides, fungicides, or fertilizers to enhance the protective or nutritive aspects of the entrapped active ingredients. However, one of the most promising and environmentally friendly technologies, biostimulants, is hardly explored in this field. Encapsulation of biostimulants could indeed be an excellent means of counteracting the problems posed by their nature: they are easily biodegradable, and most of them run off through the soil, losing most of the compounds, thus becoming inaccessible to plants. In this respect, encapsulation seems to be a practical and profitable way to increase the stability and durability of biostimulants under field conditions. This review paper aims to provide researchers working on plant biostimulants with a quick overview of how to get started with encapsulation. Here we describe different techniques and offer protocols and suggestions for introduction to polymer science to improve the properties of biostimulants for future agricultural applications.
ITS Metabarcoding Reveals the Effects of Oregano Essential Oil on Fusarium oxysporum and Other Fungal Species in Soil Samples
Authors: Karapetsi Lefkothea , Pratsinakis Emmanouil , Xirakias Fotis , Osathanunkul Maslin , Vagelas Ioannis , Madesis Panagiotis
Published: December 2022

The destructive effects of Fusarium wilts are known to affect the production of many crops. The control of Fusarium oxysporum and other soilborne pathogens was mainly based on soil fumigation (methyl bromide), which has long been prohibited and, nowadays, is based on a limited number of available fungicides due to legislation restrictions on residue tolerances and environmental impacts. Alternatively, natural and environmentally safe compounds, such as essential oils, are being investigated for their efficacy in the control of soilborne diseases. The great fungicidal ability of the oregano essential oil components (carvacrol and thymol) has been reported to inhibit the germination and the mycelial development of several fungal species, including F. oxysporum. The aim of our study was to demonstrate how the metabarcoding approach can provide valuable information about the positive or negative impacts of two different doses of oregano essential oil on Fusarium oxysporum and other fungal species which were present in the studied soil samples through the amplification of the ITS1 and ITS2 regions, which were analyzed on a MiSeq platform. A higher dose of oregano essential oil decreased the abundance of F. oxysporum, along with other fungal species, but also had negative effects on Trichoderma evansii and Mortierella chlamydospora, species with possible fungicidal properties. Soil properties, essential oil properties, the fungal composition, and interactions between fungal species should be considered as factors influencing the effectiveness of essential oils as biological control agents for soilborne pathogens.
Rebalancing Nutrients, Reinforcing Antioxidant and Osmoregulatory Capacity, and Improving Yield Quality in Drought-Stressed Phaseolus vulgaris by Foliar Application of a Bee-Honey Solution
Authors: Alghamdi Sameera A. , Alharby Hesham F. , Bamagoos Atif A. , Zaki Safi-naz S. , Abu El-Hassan Abdelmonam M. A. , Desoky El-Sayed M. , Mohamed Ibrahim A. A. , Rady Mostafa M.
Published: December 2022

Bee-honey solution (BHS) is considered a plant growth multi-biostimulator because it is rich in osmoprotectants, antioxidants, vitamins, and mineral nutrients that can promote drought stress (DtS) resistance in common bean plants. As a novel strategy, BHS has been used in a few studies, which shows that the application of BHS can overcome the stress effects on plant productivity and can contribute significantly to bridging the gap between agricultural production and the steady increase in population under climate changes. Under sufficient watering (SW (100% of crop evapotranspiration; ETc) and DtS (60% of ETc)), the enhancing impacts of foliar application with BHS (0%, 0.5%, 1.0%, and 1.5%) on growth, productivity, yield quality, physiological-biochemical indices, antioxidative defense ingredients, and nutrient status were examined in common bean plants (cultivar Bronco). DtS considerably decreased growth and yield traits, green pod quality, and water use efficiency (WUE); however, application of BHS at all concentrations significantly increased all of these parameters under normal or DtS conditions. Membrane stability index, relative water content, nutrient contents, SPAD (chlorophyll content), and PSII efficiency (Fv/Fm, photochemical activity, and performance index) were markedly reduced under DtS; however, they increased significantly under normal or DtS conditions by foliar spraying of BHS at all concentrations. The negative impacts of DtS were due to increased oxidants [hydrogen peroxide (H2O2) and superoxide (O2•−)], electrolyte leakage (EL), and malondialdehyde (MDA). As a result, the activity of the antioxidant system (ascorbate peroxidase, glutathione reductase, catalase, superoxide dismutase, α-tocopherol, glutathione, and ascorbate) and levels of osmoprotectants (soluble protein, soluble sugars, glycine betaine, and proline) were increased. However, all BHS concentrations further increased osmoprotectant and antioxidant capacity, along with decreased MDA and EL under DtS. What is interesting in this study was that a BHS concentration of 1.0% gave the best results under SW, while a BHS concentration of 1.5% gave the best results under DtS. Therefore, a BHS concentration of 1.5% could be a viable strategy to mitigate the DtS impairment in common beans to achieve satisfactory growth, productivity, and green pod quality under DtS.
Pathogen Resistance Depending on Jacalin-Dirigent Chimeric Proteins Is Common among Poaceae but Absent in the Dicot Arabidopsis as Evidenced by Analysis of Homologous Single-Domain Proteins
Authors: Esch Lara , Kirsch Christian , Vogel Lara , Kelm Jana , Huwa Nikolai , Schmitz Maike , Classen Thomas , Schaffrath Ulrich
Published: December 2022

MonocotJRLs are Poaceae-specific two-domain proteins that consist of a jacalin-related lectin (JRL) and a dirigent (DIR) domain which participate in multiple developmental processes, including disease resistance. For OsJAC1, a monocotJRL from rice, it has been confirmed that constitutive expression in transgenic rice or barley plants facilitates broad-spectrum disease resistance. In this process, both domains of OsJAC1 act cooperatively, as evidenced from experiments with artificially separated JRL- or DIR-domain-containing proteins. Interestingly, these chimeric proteins did not evolve in dicotyledonous plants. Instead, proteins with a single JRL domain, multiple JRL domains or JRL domains fused to domains other than DIR domains are present. In this study, we wanted to test if the cooperative function of JRL and DIR proteins leading to pathogen resistance was conserved in the dicotyledonous plant Arabidopsis thaliana. In Arabidopsis, we identified 50 JRL and 24 DIR proteins, respectively, from which seven single-domain JRL and two single-domain DIR candidates were selected. A single-cell transient gene expression assay in barley revealed that specific combinations of the Arabidopsis JRL and DIR candidates reduced the penetration success of barley powdery mildew. Strikingly, one of these pairs, AtJAX1 and AtDIR19, is encoded by genes located next to each other on chromosome one. However, when using natural variation and analyzing Arabidopsis ecotypes that express full-length or truncated versions of AtJAX1, the presence/absence of the full-length AtJAX1 protein could not be correlated with resistance to the powdery mildew fungus Golovinomyces orontii. Furthermore, an analysis of the additional JRL and DIR candidates in a bi-fluorescence complementation assay in Nicotiana benthamiana revealed no direct interaction of these JRL/DIR pairs. Since transgenic Arabidopsis plants expressing OsJAC1-GFP also did not show increased resistance to G. orontii, it was concluded that the resistance mediated by the synergistic activities of DIR and JRL proteins is specific for members of the Poaceae, at least regarding the resistance against powdery mildew. Arabidopsis lacks the essential components of the DIR-JRL-dependent resistance pathway.
An Evidence Theory and Fuzzy Logic Combined Approach for the Prediction of Potential ARF-Regulated Genes in Quinoa
Authors: Sghaier Nesrine , Essemine Jemaa , Ayed Rayda Ben , Gorai Mustapha , Ben Marzoug Riadh , Rebai Ahmed , Qu Mingnan
Published: December 2022

Quinoa constitutes among the tolerant plants to the challenging and harmful abiotic environmental factors. Quinoa was selected as among the model crops destined for bio-saline agriculture that could contribute to the staple food security for an ever-growing worldwide population under various climate change scenarios. The auxin response factors (ARFs) constitute the main contributors in the plant adaptation to severe environmental conditions. Thus, the determination of the ARF-binding sites represents the major step that could provide promising insights helping in plant breeding programs and improving agronomic traits. Hence, determining the ARF-binding sites is a challenging task, particularly in species with large genome sizes. In this report, we present a data fusion approach based on Dempster–Shafer evidence theory and fuzzy set theory to predict the ARF-binding sites. We then performed an “In-silico” identification of the ARF-binding sites in Chenopodium quinoa. The characterization of some known pathways implicated in the auxin signaling in other higher plants confirms our prediction reliability. Furthermore, several pathways with no or little available information about their functions were identified to play important roles in the adaptation of quinoa to environmental conditions. The predictive auxin response genes associated with the detected ARF-binding sites may certainly help to explore the biological roles of some unknown genes newly identified in quinoa.
Biopolymer Gels as a Cleaning System for Differently Featured Wooden Surfaces
Authors: Lee Chaehoon , Di Turo Francesca , Vigani Barbara , Weththimuni Maduka L. , Rossi Silvia , Beltram Fabio , Pingue Pasqualantonio , Licchelli Maurizio , Malagodi Marco , Fiocco Giacomo , Volpi Francesca
Published: December 2022

The cleaning of some wooden artefacts can be challenging due to peculiar surface roughness and/or particular finishing treatments that favour the deposition of dirt and contaminants. The most common cleaning system used by conservators is agar gel, characterized by its rigidity and brittleness, which challenges the cleaning of rough and irregular surfaces typical of most wooden artefacts. In this work, alginate crosslinked with calcium (CA) and konjac glucomannan crosslinked with borax (KGB) gels were proposed to solve this issue. They were prepared and applied to smooth- and rough-surfaced mock-ups replicating wooden musical instruments’ surfaces that had been subsequently covered by artificial soiling and sweat contaminants. The mechanical properties of CA and KGB gels, including their stability over a 60-day storage time, were evaluated by a texture analyzer, while cleaning efficacy was analytically evaluated by non-invasive X-ray fluorescence mapping and profilometric investigation. CA gel appeared to have a higher tensile strength and elongation at break. KGB gel was shown to be soft and resilient, indicating its suitability for cleaning rough surfaces. After repeating the cleaning application three times on the rough-surfaced mock-ups, both the CA and KGB gels were shown to have cleaning efficacy. The results obtained with CA and KGB were compared with those from the Agar application.
A Comparative Evaluation of the Effects of Manufacturing Parameters on Mechanical Properties of Additively Manufactured PA and CF-Reinforced PA Materials
Authors: Tutar Mumin
Published: December 2022

Nowadays, 3D printers, which have a wide range of applications, continue to become widespread and are more and more common. As a result, in addition to the visuality of the parts produced with this method, their mechanical properties have gained importance depending on where they are used. In addition to the many conveniences, it provides during the design and production phases according to traditional methods the features of the printing parameters used, especially the printing direction and angle, which vary depending on the direction. For this reason, it is necessary to determine how the mechanical properties change depending on these parameters. In this study, compression, tensile, and bending tests were carried out with samples produced by the FDM method using polyamide (PA) and carbon fiber reinforced PA (PA-CF) filaments. The effects of fiber reinforcement, raster angle, and frame on the mechanical properties were evaluated. The porosity of manufactured parts was also discussed.
Electric Field Improvement for High-Voltage Bushings
Authors: Li Li , Li Qi , Xu Shuxin , Liu Rui , Dong Manling , Ying Si , Tian Jieyuan , Xin Wanpeng , Haddad Manu , Jiang Xingliang
Published: December 2022

Resin-impregnated paper (RIP) bushing has gained significant interest due to its extended application in Extra High Voltage (EHV) and Ultra High Voltage (UHV) electricity transmission systems. However, the design criterion of its overall structure, the geometry parameters of the condenser layers, and stress release devices, etc., are still not fully understood. This article proposes a unique electric field optimization technique to integrate both the analytical and the numerical methods. The charge simulation method (CSM) is employed to create the overall equipotential surface, within which the finite element analysis (FEA) is adapted to study the localized field enhancement effects, taking into consideration the multi-physics coupled fields. A case study is performed on an actual UHV bushing. The results are compared to the traditional methods, to demonstrate the benefit of the hybrid method.
Tensile Properties and Fracture Mechanism of Thermal Spraying Polyurea
Authors: Zhang Haotian , You Yongyuan , Jia Yongsheng , Hu Jianian , Li Peibo , Xie Quanmin
Published: December 2022

In this study, polyurea was experimentally tested under various spraying temperatures and pressures. The number of holes and the pore size produced after the tensile fracture of the polyurea were counted to illustrate the effect of the various spraying temperatures and pressures on the performance of the polyurea. The tensile characteristics of polyurea were greatly influenced by the spraying temperatures and pressures, according to the experimental findings and statistical analysis. The polyurea tensile performance was best when the spraying pressure was 17.25 MPa with a spraying temperature of 70 °C. The fracture mechanism was illustrated by the silver streaking phenomenon generated during the tensile stretching process. The fracture energy was absorbed by the fracture holes and pores during silver streaking, thus creating the huge gap in tensile properties.
Influence of Herbal Fillers Addition on Selected Properties of Silicone Subjected to Accelerated Aging
Authors: Sarraj Sara , Szymiczek Małgorzata , Jurczyk Sebastian
Published: December 2022

This work aims to assess the impact of the type and percentage of powdered herbs on selected properties of silicone-based composites. The matrix was an addition cross-linked platinum-cured polydimethylsiloxane. The fillers were powdered thyme and sage, which were introduced at 5, 10, and 15 wt.%. The introduced fillers differed in composition, morphology, and grain size. The grain morphology showed differences in the size and shape of the introduced fillers. The qualitative and quantitative assessment resulting from the incorporation was conducted based on tests of selected properties: density, wettability, rebound resilience, hardness, and tensile strength. The incorporation slightly affected the density and wettability of the silicone. Rebound resilience and hardness results differed depending on the filler type and fraction. However, tensile strength decreased, which may be due to the matrix’s distribution of fillers and their chemical composition. Antibacterial activity evaluation against S. aureus proved the bacteriostatic properties of the composites. Accelerated aging in PBS solution further deteriorated the mechanical properties. FTIR and DSC have demonstrated the progressive aging of the materials. In addition, the results showed an overall minimal effect of fillers on the silicone chemical backbone and melting temperature. The developed materials can be used in applications that do not require high mechanical properties.
True Molecular Composites: Unusual Structure and Properties of PDMS-MQ Resin Blends
Authors: Bakirov Artem V. , Krasheninnikov Sergey V. , Shcherbina Maxim A. , Meshkov Ivan B. , Kalinina Aleksandra A. , Gorodov Vadim V. , Tatarinova Elena A. , Muzafarov Aziz M. , Chvalun Sergey N.
Published: December 2022

Poly(dimethyl siloxane)-MQ rubber molecular composites are easy to prepare, as it does not require a heterophase mixing of ingredients. They are characterized by perfect homogeneity, so they are very promising as rubber materials with controllable functional characteristics. The manuscript reveals that MQ resin particles can significantly, more than by two orders of magnitude, enhance the mechanical properties of poly(dimethyl siloxane), and, as fillers, they are not inferior to aerosils. In the produced materials, MQ particles play a role of the molecular entanglements, so rubber molecular weight and MQ filler concentration are the parameters determining the structure and properties of such composites. Moreover, a need for a saturation of the reactive groups and minimization of the surface energy of MQ particles also determine the size and distribution of the filler at different filler rates. An unusual correlation of the concentration of MQ component and the interparticle spacing was revealed. Based on the extraordinary mechanical properties and structure features, a model of the structure poly(dimethyl siloxane)-rubber molecular composites and of its evolution in the process of stretching, was proposed.
Improvement of Fire Resistance and Mechanical Properties of Glass Fiber Reinforced Plastic (GFRP) Composite Prepared from Combination of Active Nano Filler of Modified Pumice and Commercial Active Fillers
Authors: Rakhman Andry , Diharjo Kuncoro , Raharjo Wijang Wisnu , Suryanti Venty , Kaleg Sunarto
Published: December 2022

Glass fiber reinforced plastic (GFRP) composites have great potential to replace metal components in vehicles by maintaining their mechanical properties and improving fire resistance. Ease of form, anti-corrosion, lightweight, fast production cycle, durability and high strength-to-weight ratio are the advantages of GFRP compared to conventional materials. The transition to the use of plastic materials can be performed by increasing their mechanical, thermal and fire resistance properties. This research aims to improve the fire resistance of GFRP composite and maintain its strength by a combination of pumice-based active nano filler and commercial active filler. The nano active filler of pumice particle (nAFPP) was obtained by the sol–gel method. Aluminum trihydroxide (ATH), sodium silicate (SS) and boric acid (BA) were commercial active fillers that were used in this study. The GFRP composite was prepared by a combination of woven roving (WR) and chopped strand mat (CSM) glass fibers with an unsaturated polyester matrix. The composite specimens were produced using a press mold method for controlling the thickness of specimens. Composites were tested with a burning test apparatus, flexural bending machine and Izod impact tester. Composites were also analyzed by SEM, TGA, DSC, FT-IR spectroscopy and macro photographs. The addition of nAFPP and reducing the amount of ATH increased ignition time significantly and decreased the burning rate of specimens. The higher content of nAFPP significantly increased the flexural and impact strength. TGA analysis shows that higher ATH content had a good contribution to reducing specimen weight loss. It is also strengthened by the lower exothermic of the specimen with higher ATH content. The use of SS and BA inhibited combustion by forming charcoal or protective film; however, excessive use of them produced porosity and lowered mechanical properties.
Burnout among Male Physicians: A Controlled Study on Pathological Personality Traits and Facets
Authors: Holzgang Sarah Andrea , Pazhenkottil Aju Paul , Princip Mary , Auschra Bianca , Euler Sebastian , von Känel Roland
Published: December 2022

There is a high prevalence of job burnout in physicians, impacting both the professional and personal levels. This study aimed to investigate whether physicians with burnout show specific pathological traits and facets of their personalities compared with healthy controls, according to the dimensional personality models in the ICD-11 and DSM-5. The role of perceived stress, anxiety, and depression were exploratively investigated regarding group differences. Male physicians (n = 60) were recruited into two groups (burnout vs. healthy). The Personality Inventory for the DSM-5 Brief Form Plus (PID5BF+) and the Maslach Burnout Inventory (MBI) were applied. The Wilcoxon rank-sum test (WRS) showed group differences in five of the six traits and in six of the seventeen facets of the PID5BF+. Multiple binary logistic regression, controlling for age, showed that deceitfulness (3.34 (1.36–9.35), p = 0.013) and impulsivity (10.20 (2.4–61.46), p = 0.004) significantly predicted burnout. Moreover, the WRS showed significant group differences in perceived stress, depressive, and anxiety symptoms (all p < 0.00)]. The findings suggest a relationship between pathological personality facets and burnout in a sample of male physicians. In particular, the facets of deceitfulness and impulsivity appear to play an important role. Furthermore, burnout showed well-known associations with perceived stress, depressive, and anxiety symptoms.
Art Together, Prayer Together: Relational and Revelatory Practices of Joseph Beuys, Dietrich Bonhoeffer and Leslie Iwai
Authors: Burke Meaghan
Published: December 2022

This paper investigates a theology of prayer embedded within social and artistic practice. It considers how conceptual art broadened social possibilities for art, and how for Joseph Beuys and later Leslie Iwai, these possibilities probe spiritual realities. Beuys’ democratic methodologies, considering everyone as performing the world-shaping work of the artist, were central to his practice and described by Beuys as representations of Christ. In Life Together, the artist’s contemporary, Dietrich Bonhoeffer offers his own approach to Christ’s presence within sociality. The book reflects on his time directing a seminary where communal life was not only shaped by spiritual exercises like prayer, but also enriched by the arts. Consequently, one may read Life Together as grounding for socially and spiritually attuned artistic endeavours. This has been the case in Leslie Iwai’s conceptually and communally motivated artistic practice, which has developed alongside prayer practices and her own readings of Life Together. Social-spiritual features of Beuys’ conceptual art—seeing Christ and one another concurrently—are extended in Bonhoeffer’s articulation of prayer—not only revealing God and each other but also a means of presenting one another to God. Affinities between conceptual art and prayer emerge: both may be disclosive, holding together seen and unseen realities. Iwai can be seen to work from a conceptual mode of social-spiritual disclosure, and from consonant revelatory and intercessory practices of prayer echoing those of Bonhoeffer’s Life Together.
Multi-Mode Surface Wave Tomography of a Water-Rich Layer of the Jizhong Depression Using Beamforming at a Dense Array
Authors: Wu Qingyu , Li Qiusheng , Hu Xiangyun , Lu Zhanwu , Li Wenhui , Wang Xiaoran , Wang Guangwen
Published: December 2022

Urban structure imaging using noise-based techniques has rapidly developed in recent years. Given the complexity of the cross-correlation function in high-frequency signals, here, the beamforming (BF) method was used to analyze one data set taken from a dense array in the Jizhong Depression and obtain multi-mode dispersion curves. Multi-mode surface waves improved inversion stability, reduced non-uniqueness, and yielded a one-dimensional shear wave (S-wave) velocity model. Interpolation yielded a high-resolution three-dimensional (3D) S-wave velocity model for the study area. The model shows that velocity gradually changed in the horizontal direction and greatly increased in the vertical direction, which is largely consistent with changes in the sedimentary environment related to the continuous subsidence of the Jizhong Depression since the Quaternary. A low-velocity anomaly at a depth of ~300–400 m was revealed and determined to be caused by either a deep-buried ancient river course or low-lying area. This study demonstrates the potential of the BF method for processing dense array data sets of urban exploration. The high-resolution 3D S-wave velocity model provides a new reference for studying the Quaternary structure of the Jizhong Depression, as well as groundwater resources, urban infrastructure, and underground spaces.
Use of Remotely Sensed Data for the Evaluation of Inter-Row Cover Intensity in Vineyards
Authors: Palazzi Francesco , Biddoccu Marcella , Borgogno Mondino Enrico Corrado , Cavallo Eugenio
Published: December 2022

Information on vegetation cover and soil management is used in hydrological and soil erosion modeling, but in most cases, reference values are used solely based on land use classification without considering the actual spatial and temporal variation adopted at the field scale. This work focused on the adoption of satellite optical data from the Copernicus Sentinel-2 (S2) mission to evaluate both spatial and temporal variations of vineyard ground cover. First, on a wider scale, fields were mapped by photointerpretation, and a cluster analysis was carried out. Results suggest that vineyards can be classified according to different inter-row soil management, with the best results obtained using NDVI and NDWI. A pilot area in the municipality of Carpeneto, in the wine-growing area of Alto Monferrato, was also analyzed due to the availability of reference data on inter-row vegetation cover from experimental plots. Those are set on sloping areas and present different inter-row soil managements (conventional tillage—CT, and permanent grass cover—GC). Time series of different vegetation indices (VIs) have been obtained, and both S2 native bands and the derived VIs were evaluated to assess their capability of describing the vineyard’s inter-row coverage growth trends at plot level for the agrarian year 2017–2018. Results suggest that a seasonality effect may be involved in the choice of the most suitable band or index that better describes soil coverage development at a given moment of the year. Further studies on open-source remotely sensed (RS) data could provide specific inputs for applications in erosion risk management and crop modeling.
Long-Term Variability of Atmospheric Visual Range (1980–2020) over Diverse Topography of Pakistan
Authors: Javed Sadaf , Shahzad Muhammad Imran , Abbas Sawaid , Nazeer Majid
Published: December 2022

A substantial drop in atmospheric visibility or visual range (VR) is documented in several parts of the world. We examined the long-term spatiotemporal variability in ground-based VR data for ten airports in Pakistan from 1980 to 2020. Average VR time series analysis was performed using nonparametric tests of Mann–Kendall (MK), Modified Mann–Kendall (MMK), Sen’s Slope (SS), and Sequential Mann–Kendall (SMK), followed by spatiotemporal mapping. Bad VR (<5 km) conditions prevailed over more than 60% of the study period. Noticeably, VR was better during 1991–2000 due to the high average annual rainfall (905 mm) during the 1990s. Plain areas such as Faisalabad experienced the greatest number of bad VR days with hourly (92.85%), daily (95.35%), monthly (90.97%), and seasonal (90.97%) measurements, followed by Sialkot and Multan. The VR of lowlands in central, southern, and eastern Punjab and northern, central, and eastern Sindh showed decreasing trends. In contrast, the VR in coastal areas of south and southwestern Sindh, in the western highlands, and parts of Khyber Pakhtunkhwa (KPK) province, have indicated positive trends. The results of this study will support policymakers in catering to the issue of declining VR in the region by supporting and developing strategies to limit the factor associated with VR.