bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN REWARD DAN PUNISHMENT TERHADAP KINERJA PEGAWAI BAGIAN DIVISI KEPEGAWAIAN DI KEMENTRIAN KOPERASI DAN UKM JAKARTA SELATAN
Authors: Octaviani Elisabeth , Sembiring Carrolina F. , Tampubolon Emma
Published: June 2024

Research conducted at the Ministry of Cooperatives and SMEs in South Jakarta to determine the relationship of reward and punishment to employee performance. To find reward and punishment with the performance of employees in the Ministry of Cooperatives and SMEs in South Jakarta. Data obtained through field research and library research, and the distribution of questionnaires. This research was conducted at the personnel division in the Ministry of Cooperatives and SMEs Jl.H.R.Rasuna Kav.3-4 Said in South Jakarta. The research model used in this study ie the method of literature study, field studies and questionnaires conducted systematically in accordance with the purpose of research. Samples in this study were 21 employees. The analytical method used is the T test (partial) and Spearman rank correlation analysis. The results of this study indicate that the variable reward has a positive relationship with employee performance. This has been proven through the test t, where t test results showed that the t value (2.285)> t table (2,093). And the outcome variables punishment also has a positive relationship with the employee's performance as evidenced by t, where t test results showed that the t value (2.216)> t table (2,093) Of the two independent variables most dominant have a relationship with the employee's performance is reward (X1). Advice writer is a variable reward should be considered again in the offering to employees, so that employees who have competence good performance can receive a reward with justice for what he has given to the company because in this study the variable reward also have a positive relationship to the performance of employees.
HUBUNGAN KUALITAS PELAYANAN DAN KEPERCAYAAN TERHADAP LOYALITAS PELANGGAN PADA KONSUMEN DI PT. INASA LAFACOS
Authors: Siregar Yuli Astuti , Sinaga Sautman , Tarigan Lukas
Published: June 2024

The research was carried out in PT. Inasa Lafacos to know the relationship of quality of service and trust of customer loyalty on all parts of the consumer at PT. Inasa Lafacos. As for the purpose of this research is to know the relation of quality service to customer loyalty, loyalty towards the trust relationship customers in all parts of the consumer at PT. Lafacos Inasa. The research is descriptive-correlation with sample as much as 97 of the consumer and the data were analyzed using analysis of Rank Spearman. The results of this study suggest that (1) there is a significant relationship between the quality of service of customer loyalty on the whole consumer PT. Inasa Lafacos. This is attempted with the obtained t hitung (27.809) greater than t tabel (1,985). (2) There is a significant relationship between confidence in the loyalty of customers in all parts of the consumers of PT. Inasa Lafacos. This is attempted with the obtained t hitung (13.105) greater than t tabel (1,985). Based on the results of the research, it can be concluded that the overall quality of service and trust have better relationship towards customer loyalty, then the company should further increase as do concern employees against customers, employees can meet consumer complaints properly and also employees can serve consumers well. Need for improved performance of employees at PT. Inasa Lafacos by providing training (Traning) so that employees can improve or master the skills and techniques against the implementation of a particular work. PT. Inasa Lafacos need to do a survey to consumers by way of providing a questionnaire or interview is directly related to the perceived satisfaction of consumers.
ANALISIS KEPUASAN KONSUMEN TERHADAP PELAYANAN MINI MARKET INDOMARET CIPINANG ASEM DI KELURAHAN KEBON PALA KECAMATAN MAKASAR JAKARTA TIMUR
Authors: Sitanggang Herpina Roulina , Sembiring Carolina F. , Rajagukguk Wilson
Published: June 2024

This study aims to determine how the level of customer satisfaction on service performance Indomaret Cipinang Asem. The data used in this study derived from primary data, ie data obtained by distributing questionnaires to 100 respondents. As for the secondary data obtained from the study of literature and other sources that is certainly related to this research. The method used in this study is the importance of performance analysisdengan using ANOVA tables for processing the data, while the data collection techniques using Likert scale questionnaire contained therein Cartesian diagram. Conclusions can be drawn based on the diagram Cartesian are attributes that are in quadrant A, the employees handling customer complaints properly, employees serve customers quickly, employees are scrupulous in airport shopping deals, priced accordingly between listed with the data in the computer, the availability of products in Indomaret Asem Cipinang complete, the product availability in Cipinang Indomaret Asem, the availability of adequate parking places. The attributes of the attribute that most influences customer dissatisfaction Indomaret Cipinang Asem is atibut 10 is a discrepancy between the price specified by the data on the computer. Advice can be given to Indomaret Cipinang Asem Kebon Pala is Better Indomaret Cipinang Asem Kebon Pala more attention and improve pelayananannya contained in the attributes in quadrant A, which mainly attributes 10 that is a discrepancy between listed with the data in the computer because these attributes important for customers but implementation in Cipinang Indomaret Asem not meet the interests of customers.
HUBUNGAN BUDAYA ORGANISASI DAN MOTIVASI TERHADAP KINERJA KARYAWAN BAGIAN ADMINISTRASI DI AUTO 2000-CAO JAKARTA
Authors: Anggraini Nenny , Simamora Engelina Lawita , Lumbantoruan Rutman
Published: June 2024

Research conducted at the AUTO 2000 - CAO Jakarta to determine the relationship of organizational culture and motivation on employee performance of Administration. The purpose of this study was to determine the relationship of organizational culture and employee performance, motivation and performance of employee relations, cultural relations organization and motivation on the performance of employees in the Administrative AUTO 2000-CAO Jakarta. This research is descriptive-correlational by as many as 30 employees, and the data were analyzed using Spearman Rank analysis and correlation. The results of this study indicate that (1) there is a significant relationship between organizational culture and employee performance of Administration AUTO 2000-CAO Jakarta. It ditujukkan with the obtained t (2.309) is greater than t table (2.048). (2) there is a significant relationship between motivation and performance of employees of the Administration AUTO 2000-CAO Jakarta. It ditujukkan with the obtained t (4.105) is greater than t table (2.048). (3) there is a significant relationship between organizational culture and motivation simultaneously with employee performance of Administration AUTO 2000-CAO Jakarta. It ditujukkan with Fhitung obtained (4.771) greater than F table (3,354). Based on the results, it can be concluded that the organizational culture in the company is very strong and must be protected and maintained. Organizations need to be more enthusiastic in enhancing innovation to improve the quality of work. Work motivation has also been very strong in the company. Bosses and employees motivate each other to each other and thus creating an increase in the employee morale. While in terms of performance also has been very good and still be maintained by the briefing or coffe morning in order to create good communication between employees.Key word : organizational culture, motivation, employee performance
The Effect of Inventory Management, Executive Compensation, Intelectual Capital and Leverage on Company Performance
Authors: Zulaecha Hesty Erviani
Published: June 2024

This study aims to determine the effect of inventory management, intellectual capital, executive compensation and leverage on the performance of companies in manufacturing companies listed on the Indonesia Stock Exchange with Automotive subsektor. The number of samples of this study are 14 companies in 5 periods, namely from 2011-2015. The research method used is multiple linear regression method using SPSS version 24 program. The result of this research stated that inventory management and leverage have no significant effect to company performance, while executive compensation and Intellectual Capital have positive and significant influence to company performance.Keywords: Inventory Management, Executive Compensation, Intellectual Capital, Leverage, Company Performance
The Literature Review: Corruption Behaviour and Causes
Authors: Siregar Santi Lina
Published: June 2024

Corruption is identified as a deviation from public employees against the norms held by society with the aim for personal gain. Corruption at various levels is still seen as commonplace. This paper wants to see the causes of corruption behavior. The method is literature review especially from the book of Anti Corruption Education for Higher Education from the Ministry of Education and Culture of the Republic of Indonesia. Factors that can lead to corrupt behavior can come from both internal and external. In general, factors causing corruption can occur due to political, legal, economic, and organizational factors.Keywords: Corruption Behavior, Internal Factors, External Factors.
ANALISIS PENGARUH INFORMASI AKUNTANSI DAN NON AKUNTANSI TERHADAP UNDERPRICING (STUDI PADA PERUSAHAAN SEKTOR JASA, PERDAGANGAN
Authors: Lestari Novita , Rasyid Elly , Lumbantoruan Rutman
Published: June 2024

The objective of this research is to examine the effect of companyâ€™s age, companyâ€™s size, Debt to Equity Ratio (DER), Return on Assets (ROA) and Earning Per Share (EPS). Testing hypotheses are conducted using multiple regression models with observation from 35 sample IPO in service trade and investment companies that listed in Indonesia Stock Exchange during the period of 2008-2016. The empirical result show that companyâ€™s age and DER have negative significant effect on underpricing level. However companyâ€™s size, ROa and EPS have no significant effect on underpricing level.Keywords : IPO, Underpricing, companyâ€™s age, companyâ€™s size, Debt to Equity Ratio (DER), Return on Assets (ROA), and Earning Per Share (EPS).
The Effect of EPS and Return on BEI IDX using Value Investing from Benjamin Graham
Authors: Sitorus Frangky Yosua , Hutasoit Posma Sariguna Johnson Kennedy
Published: June 2024

This study intends to analyze the value of existing companies in Indonesia Stock Exchange (BEI) to select stocks which will gain a high level of return in the long term. Using fundamental analysis method of value investing Benjamin Graham, this method is used to select undervalued stocks, stocks that are expected to provide high returns over the long term. This study was conducted on 20 companies selected according to the criteria of value investing Graham of 331 companies that listed on the BEI in the period 2005 to 2012. With those datas, the research analyze the effect of Earning Per Share (EPS) and Return of the Shares on IHSG. Pooled Least Square method with the regression equation will be obtained. The result said that changes in the value of EPS is not a significant effect on changes IHSG in BEI, but changes in the value of stock returns has significant impact on IHSG changing, while the variable IHSG simultaneously influenced by both variables, EPS and stock return variable.
The Review of National Defense Budget Policy to the Indonesian Economy
Authors: Kennedy Posma Sariguna Johnson , L.Tobing Suzanna Josephine , Lumbantoruan Rutman
Published: June 2024

In building the power of the nation, there are two main factors that must be considered, namely economic and defense factors. The ups and downs of the defense budget generally have an impact on the national economy, while the economy and defense are the main components in building the strength of a nation. The general objective from this research is to look at the picture of the effect of the threat level of Indonesia's strategic environment on defense budget policy and its effect on the national economy. From the study show that the effect of the defense budget on the economy is still very small. But indirectly, it can still keep the demand and production process, and eliminate potential threats to disturbances on aggregate demand and supply, although the potential threat from the strategic environment shows an upward trend. Increased defense budgets do not lead to a reduction in other welfare budgets such as the education budget. However, increased threats must be considered because the education process can be disrupted. Therefore, the determination of defense budget, education budget, and other welfare budget must be taken into account in a balanced manner so as to give effect of low cost opportunity.
Keywords: economy, defense, defense budget policy.
The Analysis of Bandwidth Management Implementation at Christian University of Indonesia by Using the PS3500 Bluecoat Device
Authors: Lumbantoruan Rutman
Published: June 2024

Traffic discovery is an identification process of software and traffic which passes wide area network (WAN) link. In one analyzing process, traffic discovery could identify 10 most active application in bandwidth usage, average bit use per second, and total percentage of bandwidth usage from each application. A study showed traffic network pattern and mirrored bandwidth usage pattern will change in future orderly. Network assessment report encourages traffic pattern. The key is web traffic  Hypertext Transfer Protocol (HTTP), If there is an application is considered important traffic, it should become priority. Various non business applications which in network should be limited or time controlled. Recreational traffic such as facebook and youtube will make traffic of critical application slower, it should be limited, controlled, or banned
Kata Kunci : Bandwidth, Traffic, Bluecoat
THE INFLUENCE OF CORPORATE SOCIAL RESPONSIBILITY AND CAPITAL INTENSITY TO AGGRESSIVENESS A TAX ON MINING COMPANIES THAT
Authors: Ambarita Sulastri , Pakpahan Johnson , Sidharta Juaniva
Published: June 2024

The purpose of this research to know whether there were influence corporate social responsibility (CSR) and capital intensity of tax aggressiveness company. Independent variable used in research is disclosure of corporate social responsibility and capital intensity, while dependent variable the research is aggressiveness tax. The data used funded by primary data company to a period of five years from 2011 up to 2015. The methodology used writer is the kind of research causal, to know relations independent variable and dependent variable. The hypothesis used is H0 :Î²i = 0 (no influence between CSR and capital intensity to aggressiveness taxes). HA : Î²i â‰  0 (Is influence between CSR and capital intensity to aggressiveness taxes). Significant level of used 0.05 if the value of the significance of smaller than 5 percent free Independent variable significant on dependent variables. This research result indicates that CSR and capital intensity simultaneously not affect significantly to aggressiveness tax .Keywords: CSR, capital intensity, aggressiveness tax.
THE INFLUENCE OF MACROECONOMICS VARIABLES: RUPIAH / USD, BI RATE
Authors: Sahetapy Mendy Thensya , Kennedy Posma Sariguna Johnson
Published: June 2024

2008 global economic crisis has led to poor growth across all sectors in Indonesia. The crisis also had an impact on stock market conditions that exist in Indonesia, including the shares of the manufacturing sector. The stock price itself more easily influenced by external factors or changes in macroeconomic conditions. Macroeconomic factors will continue to experience growth and development as always turmoil fluctuation, well after the global crisis well so far. Therefore, this study aims to determine how large the macro-economic factors that influence the stock return of the manufacturing sector. Macroeconomic factors that will be examined is the exchange rate USD / USD, BI rate, inflation and oil prices. The analytical method used in this research is multiple regression analysis were performed with SPSS 23. One of the requirements to perform multiple test analysis necessary to test classic assumptions. This is necessary so that the resulting regression equation is BLUE (Best, Linear, Unbiased, Estimator). In addition to assessing the goodness of fit of a model made for the t-test, F, and test the coefficient of determination. This study uses monthly data from 2006-2015. The results of this study indicate that the variable Exchange Rate / USD, oil prices negatively affect Sunia Stock Return manufacturing sector 2006-2008 period and a variable BI Rate, Oil Price Inflation influence positively and negatively affect the manufacturing sector Stock Return period 2010-2015.Keywords: global crisis in 2008, Manufacturing Sector, Exchange Rate, BI Rate, Inflation, Oil Price, Stock Return.
THE NORMATIVE STUDY ON THE AREA/SPACE STRUCTURE POLICY OF STATE BORDER IN MALUKU PROVINCE
Authors: Kennedy Posma Sariguna Johnson , L.Tobing Suzanna Josephine , Heatubun Adolf , Lumbantoruan Rutman
Published: June 2024

The purpose of this paper is to review the management of border area functions in accordance with the mandate of Law no. 43 of 2008 on National Territory. This study is based on the Master Plan for State Boundary Management, and the Priority Location Master Plan, which is a common reference for all stakeholders. In this research, as the methodology used is the review literature using qualitative normative method. This means to review the regulations related to the arrangement of spatial function of State Border Area in Maluku Province. Spatial Planning of Border Areas in Maluku Province aims: To create a state defense and security function that ensures the integrity of the territorial sovereignty and order which borders are the State of Timor Leste and the State of Australia; Effective protected areas to protect biodiversity, protected forests, and coastal borders including in small outer islands (PPKT) and; Make border areas that are self-reliant and competitive.Keywords: State Border Area, National Strategic Activities Center (PKSN), Priority Location (Lokpri), Spatial Plan (RTRW)
The Analysis of Training Factors and Motivational Factors to Improve the Performance of Employees of PT. Bank Victoria (PT.BA)
Authors: Novita Yohana , Tobing Suzanna Josephine L. , Kennedy Posma Sariguna Johnson
Published: June 2024

This study aims to analyze (1) whether there was a relationship between training factors and the performance of employees of PT. Bank Victoria International Tbk (PT.BV); (2) is there a relationship between motivational factors and the performance of employees of PT. Bank Victoria. The next results in this study are (1) there is a relationship between training factors and the performance of employees of PT. Bank Victoria. This is indicated by the significance value smaller than 0.05 is (0,000) <(0.005). With Spearman rank correlation coefficient of 0.481. (2) there is a relationship between motivational factors and the performance of employees of PT. Bank Victoria. This is indicated by the significance value smaller than 0.05 is (0,000) < (0.005). With Spearman rank correlation coefficient of 0.453. Keyword : training factors, motivation factors, employee performance
ANALISIS RATIO LAPORAN KEUANGAN PERUSAHAAN DAGANG MENGGUNAKAN ZAHIR ACCOUNTING VERSI 5.1
Authors: Ela Revita Maria Lapriska Dian , Rahmayani Fanny , Ariyati Indah
Published: June 2024

The role of information technology is very important because the existence of information technology can facilitate operations in their business fields. One of the information that is needed by the company is financial report to find out how the company is developing. The financial statements are information used by management for the decision making of the Bekasi Amanah Telaga Harapan Cooperative having its address at Danau Duta Utara Blok D1, Harapan Baru Sub-District, North Bekasi District. Currently the Amanah Telaga Harapan Bekasi Cooperative in making financial reports for the period every month is still manua.. The computerized system is able to produce more precise and accurate information to help smooth daily work. By using the zahir accountuing application version 5.1, companies can easily and quickly obtain Financial Statements and Financial Statement Analysis that are beneficial to the company and its business management and face competition. By analyzing the financial statements the company can identify some of the company's financial strengths and weaknesses. Financial Statement Analysis is also useful as a tool for predicting / estimating assets, debt, capital, cash flow, profit sharing in the future, and predicting the bankruptcy of a company in the future. The use of this application program can be beneficial for the company, so the company can evaluate the financial position and financial performance of the company so that it can improve services to members of the cooperative, related parties, determine corrective measures so you can win the competition and make the best profit.
 
Keywords: Financial Statement Analysis, Trading Companies, Zahir Accounting
ANALISIS BRAND EQUITY, BRAND AWARENESS, DAN ATTITUDE TERHADAP PURCHASE INTENTION AIR MINUM DALAM KEMASAN MEREK LE MINERALE (STUDI KASUS MAHASISWA DI UNIVERSITAS KRISTEN INDONESIA)
Authors: . Meysyahdamay , Tobing Fenny BNL. Tobing
Published: June 2024

Le Minerale is a brand of bottled mineral in Indonesia, purchased by PT. Tirta Fresindo Jaya which isa subsidiary of Mayora Indah, Engaged in the beverages sector. Brand equity, brand awareness, andattitudestowards consumersâ€™ purchase intentionof the Le Minerale brand, to students atChristian University of Indonesia, Jakarta.The research method used by author is qualitative descriptive. For data analysis techniques carried out by author is usingquality test data (validity and reliability test) Spearman Rank test, and Likert Score to prove or know the statistical test.
 Keywords : brand equity, brand awareness, attitude, purchase intention, atittudes and Spearman Rank
DAFTAR ISI DAN PEDOMAN PENULISAN
Authors: Lumbantoruan SE., MM Rutman
Published: June 2024

-
The Influence of Profitability Liquidity, Leverage and Growth on Dividend Policies and Free Cash Flow as Moderating Variable In The Companies Listed on The Indonesia Stock Exchange Year 2015-2017
Authors: Situmorang Humala
Published: June 2024

One of the objectives of investors to invest is to increase their wealth. Added wealth is obtained through dividends distributed by company management. Management’s decision to divide dividends (dividend policy) is an attraction for investors to buy company shares even at high prices so that it will strengthen the company’s cash position to be used to run company operations with the aim of gaining high profits and increasing company value. The high value of the company will make it easier for management to raise funds. Logically high profits will produce high liquidity, with high liquidity in addition to being able to pay off all of its obligations as well as being able to finance the growth of the company and set aside free cash to be distributed to shareholders as dividends. Therefore the purpose of this study is to examine whether free cash flow can strengthen or weaken profitability, liquidity, leverage and growth towards management policies to pay dividends. Using a sampling purpose, the company’s sampling consists of 31 companies listed on the Indonesia Stock Exchange in 2015-2017. For testing used logistic regression analysis consisting of logistic regression test, significant test of fit model with the approach of maximum likelihood method and partial test and model formation. The results of this study indicate that free cash flow cannot encourage / strengthen the influence of profitability, liquidity, leverage and growth on dividend policy, so that profitability, liquidity, leverage and growth have no effect on dividend policy. Keywords: Profitability, liquidity, leverage, growth, free cash flow and dividend policy.
THE INFLUENCE OF FINANCIAL PERFORMANCE TOWARDS FOOD SUBSTRATE MANUFACTURING COMPANY'S RETURNBEVERAGES IN THE PACKAGES ARE EXISTING AND REGISTERED IN INDONESIA STOCK EXCHANGE PERIOD OF 2013-2017
Authors: Sipayung Monita Herawaty , Tarigan Lukas
Published: June 2024

He problem of the main objective of investors to invest their funds in the capital market is, among others, to get a maximum return on certain risks. Investors are interested in stocks that have positive and high returns because they will improve the welfare of investors. To attract investors, companies and improve their financial performance. Measurement of financial on thee performance can be done using financial ratios. so in this case if the financial performance of a company is good, it will automatically also affect the stock price movements in the capital market. As study To determine whether the measured financial performance is through the financial ratios of Gros Profit Margin (GPM) Earning Per Share (EPS), Debit to Equity Ratio (DER), Return on Equity (ROE), Return on Assets ( ROA) has a significant effect on stock returns. there is also a method that is used in this fixing is Addit Market Value (MVA) analysis, t test analysis and also F test is used by a sample of 8 companies through purposive sampling method. The results obtained in this study prove that the MVA analysis proves that the company's development moves simultaneously and is seen partially only Gros Profit Margin (GPM), which affects the Stock Return, but if viewed simultaneously addressing the four variables that affect significant to Stock Returns.
 
Keywords: Gros Profit Margin , Earning Per Share, Debit to Equity Ratio, Return on Equity, Return on Asset
THE Implementation and Analysis of Internet Networking Monitoring System with Hillstone Hardware at Indonesian Christian University
Authors: Lumbantoruan Rutman
Published: June 2024

Computer Internet Network Monitoring is a computer system managing activity connected to many servers in an organization. This monitoring system is used to help adjusting and monitoring server network continuously. Internet connection monitoring has benefit in bandwidth usage monitoring for every user, either it is being used or not. Network monitoring is created by installing Hillston Hardware in Information System Implementation Unit. A trouble usually happened when slow loading time occurred in online registration hence error network in consequence. A result obtained after Hillstone Hardware implementation is centre of data staffs could detect network trouble and simplify its handling. Hillstone is reliable to monitor undergoing internet data services in user and network, also activates warning system to user connecting to improper internet network or bandwidth.
 
Keywords: Monitoring, Internet connection analysis, Hillstone, server, bandwidth
THE INFLUENCE OF SALES GROWTH, CAPITAL INTENSITY, AND CORPORATE SOCIAL RESPONSIBILITY TO TAX AGGRESSIVENESS CASE STUDIES OF MANUFACTURING COMPANIES REGISTERED ON THE IDX 2014-2018
Authors: Ambarjati Laurensia Hanny , Siswoadmojo Sistomo , Regina Desideria
Published: June 2024

The purpose of this research is to see whether there is an influence between sales growth, capital intensity, and corporate social responsibility on tax aggressiveness in manufacturing companies listed on the IDX in 2014-2018. This study uses a quantitative approach, and usesmultiple regression analysis to test sales growth, capital intensity, and corporate social responsibility towards tax aggressiveness. From the results of statistical tests, it is found that sales growth and capital intensity have no partial or significant effect on tax aggressiveness, while corporate social responsibility has a partial and significant effect on tax aggressiveness.Keywords: Sales Growth, Capital Intensity, tax aggressiveness
THE RELATIONSHIP BETWEEN LEADERSHIP STYLE AND ORGANIZATIONAL COMMUNICATION ON EMPLOYEE PERFORMANCE
Authors: Claudia Rosalita , Tampubolon Emma , Sunaryo Tarsicius
Published: June 2024

This research aims to determine how the relationship between leadership style and organizational communication on employee performance at Pondok Kelapa coffee shop. The data used in this study are secondary data in the form of primary data and secondary data. Primary data used by providing a list of questions (questionnaire) to respondents and secondary data through journals that support this research. The data analysis method used is non-parametric statistics using SPSS (Statistical Package for Social Sciences) software which can be used in social research. The hypothesis used is the Spearman Rank correlation analysis statistical technique. Based on the results of data analysis, there is no significant relationship between leadership style and employee performance of Kopiyor Pondok Kelapa as indicated by the value of tcount (1.760) <ttable (2.160). There is a significant relationship between organizational communication and employee performance of Kopiyor Pondok Kelapa which is indicated by the value of t (3.267) <t table (2.160). The author's suggestions regarding the leadership style of the leader must be able to provide motivation when employees work and continue to improve in providing direction to employees so that employee performance increases. Regarding organizational communication, the leader must be able to properly accept any complaints while working and regarding the performance of employees, employees must be able to make decisions on minor problems, fellow employees must help each other in completing tasks.
Keywords:leadership style, organizational communication and employee performance.
ENGLISH LANGUAGE PROFICIENCY AS LINGUISTIC CAPITAL AMONG BANGLADESHI GRADUATES
Authors: RAMALINGAM Selvajothi , ISLAM Md Tarikul
Published: June 2024

English language proficiency is considered an essential tool for Bangladeshi graduates to use in various aspects such as ensuring job security, attaining higher education, securing international business, using social networking, and communicating with friends and families. English language proficiency in personal development relates to Pierre Bourdieu’s (1986) concept of cultural capital in language learning and practice among Bangladeshi graduates. This study aimed to identify how graduates use English language as linguistic capital in the Bangladeshi context. This qualitative research utilised a phenomenological research design and thematic analysis. Purposive sampling technique was used to collect the data through face-to-face interviews involving 20 Bangladeshi graduates in the capital city Dhaka. The results indicate that English language proficiency is used as linguistic capital, which converts into economic capital in developing a career, earning money, and gaining prestige in communication. This study contributes to promoting an awareness among graduates to use English as linguistic capital in individual and national development.
Radioprotective effect of polyvinylpyrrolidone modified selenium nanoparticles and its antioxidation mechanism in vitro and in vivo
Authors: Li Wei , Lu Xianzhou , Jiang Liangjun , Wang Xiangjiang
Published: June 2024

Objective

Polyvinylpyrrolidone (PVP) is a commonly used biomedical polymer material with good water solubility, biocompatibility, low immunogenicity, and low toxicity. The aim of this study is to investigate the antioxidant mechanism and clinical potential of PVP modified selenium nanoparticles (PVP-Se NPs) as a new radioprotective agent.

Methods

A laser particle size analyzer and transmission electron microscope were used to characterize PVP-Se nanoparticles prepared by chemical reduction. Human umbilical vein endothelial cells (HUVECs) were used to evaluate the radiation protective effects of PVP-Se NPs. SD rats were employed as an in vivo model to identify the most effective concentration of PVP-Se NPs and assess their potential radioprotective properties. Western blot (WB) was used to detect the expression of nuclear factor kappa-B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling proteins in human umbilical vein endothelial cells (HUVECs) and rat liver and kidney tissues.

Results

PVP-Se NPs could reduce the oxidative stress injury and inflammatory response caused by X-ray irradiation in HUVECs and rats, and inhibit cell apoptosis by modulating NF-κB and MAPK signaling pathways. PVP-Se NPs could increase HUVECs viability, reduce apoptosis, inhibit inflammatory factors IL-1β, IL-6 and TNF-α, improve the survival rate of rats, promote antioxidant enzyme activities in cells and rats, reduce malondialdehyde concentration in serum, and reduce the expression of inflammatory factors such as IL-1β, IL-6 and TNF-α in cell supernatant and liver and kidney tissues. PVP-Se NPs could significantly reduce the phosphorylation levels of NF-κB and MAPK pathway-associated proteins in HUVECs and rat liver and kidney tissues (p < 0.05).

Conclusion

PVP-Se NPs can protect against radiation-induced oxidative damage by modulating NF-kB and MAPK pathways, providing a theoretical basis and experimental data for their use as an effective radioprotective agent.
Biomechanical analysis of the tandem spinal external fixation in a multiple-level noncontiguous lumbar fractures model: a finite element analysis
Authors: Chen Huarong , Kang Yu , Yan Yiguo , Wang Hu , Peng Wen , Liao Yijia , Zou Mingxiang , Xu Zhun , Song Xizheng , Wang Wenjun , Wang Cheng
Published: June 2024

Objective

This study aimed to investigate the biomechanical characteristics of the tandem spinal external fixation (TSEF) for treating multilevel noncontiguous spinal fracture (MNSF) using finite element analysis and provide a theoretical basis for clinical application.

Methods

We constructed two models of L2 and L4 vertebral fractures that were fixed with the TSEF and the long-segment spinal inner fixation (LSIF). The range of motion (ROM), maximum stresses at L2 and L4 vertebrae, the screws and rods, and the intervertebral discs of the two models were recorded under load control. Subsequently, the required torque, the maximum stress at L2 and L4 vertebrae, the screws and rods, and the intervertebral discs were analyzed under displacement control.

Results

Under load control, the TSEF model reserved more ROM than the LSIF model. The maximum stresses of screws in the TSEF model were increased, while the maximum stresses of rods were reduced compared to the LSIF model. Moreover, the maximum stresses of L2 and L4 vertebrae and discs in the TSEF model were increased compared to the LSIF model. Under displacement control, the TSEF model required fewer moments (N·mm) than the LSIF model. Compared to the LSIF model, the maximum stresses of screws and rods in the TSEF model have decreased; the maximum stresses at L2 and L4 in the TSEF model were increased. In the flexion condition, the maximum stresses of discs in the TSEF model were less than the LSIF model, while the maximum stresses of discs in the TSEF model were higher in the extension condition.

Conclusion

Compared to LSIF, the TSEF has a better stress distribution with higher overall mobility. Theoretically, it reduces the stress concentration of the connecting rods and the stress shielding of the fractured vertebral bodies.
The association between lactate dehydrogenase to serum albumin ratio and in-hospital mortality in patients with pulmonary embolism: a retrospective analysis of the MIMIC-IV database
Authors: Hu Jingjing , Zhou Yidan
Published: June 2024

Background

Lactate dehydrogenase (LDH) and albumin (ALB) were found to be significantly correlated with mortality in pulmonary embolism (PE) patients. However, data regarding the LDH/ALB ratio (LAR) in patients with acute PE are scanty. Therefore, the aim of this study was to investigate the association between LAR and the risk of mortality in patients with acute PE.

Methods

A retrospective cohort study was conducted on patients with acute PE represented in the Medical Information Mart for Intensive Care IV (MIMIC-IV). A receiver operating characteristic (ROC) curve analysis and calibration curve were used to assess the accuracy of the LAR for predicting mortality in patients with acute PE. We utilized Cox regression analysis to determine adjusted hazard ratios (HR) and 95% confidence interval (CI). Survival curves were used to evaluate a connection between the LAR and prognosis in patients with acute PE.

Results

The study comprised 581 patients, and the 30-day all-cause mortality rate was 7.7%. We observed a higher LAR in the non-survival group compared to the surviving group (21.24 ± 21.22 vs. 8.99 ± 7.86, p < 0.0001). The Kaplan–Meier analysis showed that patients with an elevated LAR had a significantly lower likelihood of surviving the 30-day mortality compared to those with a low LAR. Cox regression analysis showed that LAR (HR = 1.04, 95% CI: 1.03–1.05) might have associations with 30-day mortality in patients with acute PE. This result was supported by sensitivity analyses. According to the results of the ROC curve analysis, the LAR's prediction of 30-day mortality in patients with acute PE yielded an area under the ROC curve of 0.73. A calibration curve showed LAR is well calibrated.

Conclusion

Our research suggests LAR monitoring may be promising as a prognostic marker among patients with acute PE.
Childhood craniopharyngioma: a retrospective study of children followed in Hôpital Universitaire de Bruxelles
Authors: Magerman Clémentine , Boros Emese , Preziosi Marco , Lhoir Sophie , Gilis Nathalie , De Witte Olivier , Heinrichs Claudine , Salmon Isabelle , Fricx Christophe , Vermeulen Françoise , Lebrun Laetitia , Brachet Cécile , Rodesch Marine
Published: June 2024

Introduction

Craniopharyngiomas (CPs) are benign brain tumors accounting for 5 - 11% of intracranial tumors in children. These tumors often recur and can cause severe morbidity. Postoperative radiotherapy efficiently controls and prevents progression and recurrence. Despite advancements in neurosurgery, endocrinological, visual, and neuropsychological complications are common and significantly lower the quality of life of patients.

Methods

We performed a retrospective study, including all patients younger than sixteen diagnosed with CP between July 1989 and August 2022 and followed up in Hôpital Universitaire de Bruxelles.

Results

Nineteen children with CP were included, with median age of 7 years at first symptoms and 7.5 at diagnosis. Common symptoms at diagnosis were increased intracranial pressure (63%), visual impairment (47%), growth failure (26%), polyuria/polydipsia (16%), and weight gain (10.5%). As clinical signs at diagnosis, growth failure was observed in 11/18 patients, starting with a median lag of 1 year and 4 months before diagnosis. On ophthalmological examination, 27% of patients had papillary edema and 79% had visual impairment. When visual disturbances were found, the average preoperative volume was higher (p=0.039). Only 6/19 patients had gross total surgical resection. After the first neurosurgery, 83% experienced tumor recurrence or progression at a median time of 22 months. Eleven patients (73%) underwent postsurgical radiotherapy. At diagnosis, growth hormone deficiency (GHD) was the most frequent endocrine deficit (8/17) and one year post surgery, AVP deficiency was the most frequent deficit (14/17). Obesity was present in 13% of patients at diagnosis, and in 40% six months after surgery. There was no significant change in body mass index over time (p=0.273) after the first six months post-surgery.

Conclusion

CP is a challenging brain tumor that requires multimodal therapy and lifelong multidisciplinary follow-up including hormonal substitution therapy. Early recognition of symptoms is crucial for prompt surgical management. The management of long-term sequelae and morbidity are crucial parts of the clinical path of the patients. The results of this study highlight the fundamental importance of carrying out a complete assessment (ophthalmological, endocrinological, neurocognitive) at the time of diagnosis and during follow-up so that patients can benefit from the best possible care.
Correlation between degeneration of cervical intervertebral disc and degeneration of paravertebral muscle
Authors: Li Qiujiang , Long Xingxia , Wang Rui , Niu Pengying , Cai Lijun , Wang Lei , Song Yueming
Published: June 2024

Objective

To investigate the relationship between degeneration of cervical intervertebral disc and degeneration of paravertebral muscles[multifidus (MF), cervical semispinalis (SCer), semispinalis capitis (SCap) and splenius capitis (SPL)].

Methods

82 patients with chronic neck pain were randomly selected, including 43 males and 39 females, with 50.73 0.7.51 years old. All patients were scanned by 3.0T MRI Philips Ingenia performed conventional MRI sequence scanning and fat measurement sequence mDIXON-Quant scanning of cervical. Fat infiltration (FI) and cross-sectional area (CSA) of cervical paravertebral muscle (MF, SCer, SCap and SPL) at central level of C5–6 disc were measured by Philips 3.0T MRI image post-processing workstation. According to Pfirrmann grading system, there was no grade I in the included cases. The number of grade IIr IV cases were n=16, 40, 19 and 7 respectively. CSA and FI of cervical paravertebral muscles were compared with t test or one-way ANOVA, Spearman correlation analysis was used to evaluate the correlation between age, disc degeneration, and CSA, FI of cervical paravertebral muscles, and multiple linear regression analysis was used to analyze the independent influencing factors of CSA and FI.

Results

CSA of cervical paravertebral muscles in male patients was significantly higher than that in female patients (all P<0.001), but there was no significant difference in FI (all P>0.05). Age was weakly correlated with CSA of MF+SCer, moderately correlated with CSA of SCap and SPL (r=-0.256, -0.355 and -0.361, P<0.05), weakly correlated with FI of SCap and SPL (r= 0.182 and 0.264, P<0.001), moderately correlated with FI of MF+SCer (r=0.408, P<0.001). There were significant differences in FI with disc degeneration (P<0.001, P=0.028 and P=0.005). Further correlation analysis showed that disc degeneration was strongly correlated with FI of MF+SCer (r=0.629, P<0.001), and moderately correlated with FI of SCap and SPL (r=0.363, P=0.001; r=0.345, P=0.002). Multiple linear regression analysis showed that sex and age were the influencing factors of CSA of SCap and SPL, sex was the independent influencing factor of CSA of MF+SCer, and disc degeneration was the independent influencing factor of FI.

Conclusions

Age is negatively correlated with CSA and positively correlated with FI. Disc degeneration was correlated with FI of paravertebral muscles, especially with FI of MF and SCer. Sex and age were the influencing factors of CSA, while disc degeneration was the independent influencing factor of FI.
Identifying and evaluating a disulfidptosis-related gene signature to predict prognosis in colorectal adenocarcinoma patients
Authors: Li Ming , Wang Jin , Zhao Yuhao , Lin Changjie , Miao Jianqing , Ma Xiaoming , Ye Zhenyu , Chen Chao , Tao Ke , Zhu Pengcheng , Hu Qi , Sun Jinbing , Gu Jianfeng , Wei Shaohua
Published: June 2024

Disulfidptosis, a regulated form of cell death, has been recently reported in cancers characterized by high SLC7A11 expression, including invasive breast carcinoma, lung adenocarcinoma, and hepatocellular carcinoma. However, its role in colon adenocarcinoma (COAD) has been infrequently discussed. In this study, we developed and validated a prognostic model based on 20 disulfidptosis-related genes (DRGs) using LASSO and Cox regression analyses. The robustness and practicality of this model were assessed via a nomogram. Subsequent correlation and enrichment analysis revealed a relationship between the risk score, several critical cancer-related biological processes, immune cell infiltration, and the expression of oncogenes and cell senescence-related genes. POU4F1, a significant component of our model, might function as an oncogene due to its upregulation in COAD tumors and its positive correlation with oncogene expression. In vitro assays demonstrated that POU4F1 knockdown noticeably decreased cell proliferation and migration but increased cell senescence in COAD cells. We further investigated the regulatory role of the DRG in disulfidptosis by culturing cells in a glucose-deprived medium. In summary, our research revealed and confirmed a DRG-based risk prediction model for COAD patients and verified the role of POU4F1 in promoting cell proliferation, migration, and disulfidptosis.
Research progress of SIRTs activator resveratrol and its derivatives in autoimmune diseases
Authors: Yu Xiaolong , Chen Mingkai , Wu Jiabiao , Song Ruixiao
Published: June 2024

Autoimmune diseases (AID) have emerged as prominent contributors to disability and mortality worldwide, characterized by intricate pathogenic mechanisms involving genetic, environmental, and autoimmune factors. In response to this challenge, a growing body of research in recent years has delved into genetic modifications, yielding valuable insights into AID prevention and treatment. Sirtuins (SIRTs) constitute a class of NAD-dependent histone deacetylases that orchestrate deacetylation processes, wielding significant regulatory influence over cellular metabolism, oxidative stress, immune response, apoptosis, and aging through epigenetic modifications. Resveratrol, the pioneering activator of the SIRTs family, and its derivatives have captured global scholarly interest. In the context of AID, these compounds hold promise for therapeutic intervention by modulating the SIRTs pathway, impacting immune cell functionality, suppressing the release of inflammatory mediators, and mitigating tissue damage. This review endeavors to explore the potential of resveratrol and its derivatives in AID treatment, elucidating their mechanisms of action and providing a comprehensive analysis of current research advancements and obstacles. Through a thorough examination of existing literature, our objective is to advocate for the utilization of resveratrol and its derivatives in AID treatment while offering crucial insights for the formulation of innovative therapeutic approaches.