bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of hand eczema severity on quality of life in workers engaged in lock making: A cross-sectional study from tertiary care hospital
Authors: Siddiqui Moin Ahmad , Sarshar Fariz , Saraswat Ambika
Published: February 2023

Objectives:

Hand eczema is a frequent condition that dermatologists commonly encounter. It leads to considerable impact on quality of life (QOL) by significant functional impairment, disruption of work, and discomfort in the working population. The symptoms range from a minor discomfort to a serious debilitating and long-term conditions. Workers engaged in lock making constitute an economically poor section of society. They are exposed to different kinds of allergens, hence are predisposed to develop hand eczema. The aim of this study was to study the impact of hand eczema on the QOL in workers engaged in lock making.

Materials and Methods:

A total of 65 workers engaged in lock making and suffering from hand eczema, who visited the out-patient department of dermatology for 6 months, were included in this study. Data on QOL were obtained through a questionnaire devised by Finlay et al. Hand eczema severity index (HECSI) was used to assess the severity of disease. Associations were drawn regarding Dermatology Life Quality Index (DLQI) and HECSI scores with age, sex, duration of disease, number of episodes of illness, and number of sick leaves.

Results:

Sixty-five patients suffering from hand eczema and engaged in lock making participated in this study, of which 52 (80%) were male and 13 (20%) were female. The commonest age group affected was 36–40 years (41.53%). The most common morphological pattern seen was hyperkeratotic palmar eczema in 50.7% (n = 33) patients followed by chronic dry fissured eczema in 35.3% (n = 23). The mean HECSI score was 19.52 (Standard deviation [SD] = 9.416) and mean DLQI score was 9.92 (SD = 2.426). A significant association of DLQI was seen with duration of disease (P = 0.011), number of episodes of eczema (P = 0.003), and number of sick leaves taken (P = 0.005). Similarly, HECSI score showed significant association with duration of disease (P = 0.002) but not with number of episodes of eczema (P = 0.056). No significant association was found between hand eczema severity and QOL. Being a OPD-based study, it may not truly reflect the community data. Patch test could not be done as workers were poor and could not afford it.

Conclusion:

Lock makers with hand eczema showed considerable impairment of their QOL. Further, they are more prone to absenteeism from work.
An N-terminal peptide of Tar DNA binding Protein 43 lacking nuclear localization signal translocates to the nucleus of GC-1 spermatogonial cells
Authors: Varghese Divya Saro , Vysakh Gopinath , Kumar Pradeep G.
Published: February 2023

Objectives:

TAR DNA-binding protein of 43 kDa (TDP-43) is an RNA/DNA binding protein expressed in the brain and the testis. Mutations in TDP-43 lead to mislocalization and cytoplasmic aggregation of this protein causing neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal dementia. TDP-43 has also been implicated in maintaining spermatogenesis. While homodimerization of TDP-43 is critical for its physiological functions, higher-order aggregation of this protein impairs its functions. This study was aimed to map the critical amino acids of the N-terminus of this protein in mediating its homodimerization.

Materials and Methods:

We generated deletion constructs of Tdp-43 containing NRRM1 domain alone (TDP-43∆3-183) and N-terminal peptide of TDP-43 which lacks the nuclear localization signal (NLS) (TDP-43∆1-50) with fluorescent reporters having non-overlapping emission properties. These constructs were co-transfected into a mouse spermatogonial cell line to examine their dimerization and nuclear translocation capabilities in vitro.

Results:

We found that TDP-43∆3-183 alone was not capable of homodimerization. On the other hand, TDP-43∆1-50 when co-transfected into GC1-spg cells along with full length TDP-43 translocated to the nucleus oligomerized with the latter and translocated to the nucleus, indicating the importance of amino acids 1-50 of TDP-43 in dimerization.

Conclusion:

The N-terminal segment of TDP-43 spanning amino acids 1-50 is responsible for dimerization, while that spanning amino acids 51-183 directs it to the nucleus.The physiological and pathological implications of this finding need to be examined.
Investigating the Impact of Growth Temperatures on the ZnO Nanorods Properties Grown with Simplest Spray Technique
Authors: Jaqsi Mohammed Kadhim , Kareem Awaz , Abdulrahman Ahmed
Published: February 2023

The simplest chemical spray approach has been used to grow the zinc oxide (ZnO) nanorods (NRs). For spraying, a basic perfume automizer was employed. Additionally, utilizing a variety of characterization techniques, the effects of various growth temperatures on the ZnO NRs properties were looked into and evaluated. The results of the investigation demonstrated that the growing temperature significantly affects all-characteristics properties of the ZnO NRs fabricated using the most straightforward spray approach. At various growth temperatures, the average diameters (size) and average crystalline sizes along with (002) of grown ZnO NRs were in the ranges of (47.89-51.29) nm and (44.128-52.565) nm, respectively. The hexagonal wurtzite plane was the optimum direction for ZnO NRs to be oriented, and as growth temperatures are raised. The absorption edge changed toward longer wavelengths and as growth temperature increased, the average absorbance also increased. The optical analysis reveals that the direct Eg. of the produced ZnO NRs lies in the (3.182-3.250) eV range.
THE USE OF CRISPR IN ANIMAL HUSBANDRY AND AQUACULTURE
Authors: Жаркова Е.К. , Селионова М.И. , Жевнеров А.В.
Published: February 2023

Неизменный рост спроса на продукцию животноводства и аквакультуры диктует разработку новых и совершенствование существующих технологий увеличения продуктивности животных и рыбы, повышения их устойчивости к болезням, контроля восприимчивости к возбудителям зоонозных заболеваний. Для генетического улучшения экономически важных признаков скота и ценных видов водных биоресурсов разработаны CRISPR-ориентированные технологии редактирования геномов. В тоже время такие методы не безошибочны и могут приводить к нежелательным результатам, что требует дальнейших исследований и совершенствования приемов геномных изменений.

The constant growth livestock and fish farming products demand creates prerequisites for correcting economically valuable traits, increasing resistance to diseases, and controlling susceptibility to pathogens of zoonotic diseases. CRISPR genome editing technologies have been developed for livestock and valuable aquaculture species genetic improvement, but such methods are not infallible and can lead to undesirable results.
VARIABILITY OF MORPHOLOGICAL TRAITS OF THE PURPLE APPLE TREE IN THE COLLECTION OF GBS RAS
Authors: Донских В.Г. , Аниськина Т.С. , Бондорина И.А. , Крючкова В.А.
Published: February 2023

Яблоня является наиболее распространенной плодовой культурой в мире. Она обладает широким адаптивным потенциалом. Данные по Malus x purpurea собраны в 2021 году в коллекции ботанического сада в Москве. Отмечено 17 количественных и описаны 26 качественных признаков побега, листа, цветка и плода. Установлено, что признаки цветка и листа имеют преимущественно очень низкую вариацию (степень полиморфизма средняя у длины пыльника 24,9% и у длины черешка 19,8%). Высокая вариация отмечена у числа семян в плоде (50,3%) и у массы семян (55,3%), а у массы плода – средняя (20,9%). Установлен размах изменчивости признаков для всех количественных признаков и рассчитаны уравнения регрессии для массы плода, массы семян, диаметра плода, числа семян в плоде, числа цветков в щитке.

The apple tree is the most widespread fruit crop in the world. It has a wide adaptive potential. Data on Malus x purpurea were collected in 2021 from the collection of the Botanical Garden in Moscow. 17 quantitative and 26 qualitative signs of the shoot, leaf, flower and fruit were noted. It was found that the characteristics of the flower and leaf have predominantly very low variation (the degree of polymorphism is average for the length of the anther 24.9% and for the length of the petiole 19.8%). A high variation was noted in the number of seeds in the fruit (50.3%) and in the mass of seeds (55.3%), and in the mass of the fruit – average (20.9%). The range of trait variability for all quantitative traits was established and regression equations were calculated for fruit weight, seed weight, fruit diameter, number of seeds in a fruit, and number of flowers in a corymb.
FLORISTIC ANALYSIS OF PLANT COMMUNITIES WITH PARTICIPATION OF TROLLIUS EUROPAEUS L. ON THE TERRITORY OF THE TRANS-URALS OF THE REPUBLIC OF BASHKORTOSTAN
Authors: Ильина И.В. , Папян Э.Э. , Суюндуков И.В. , Ягафарова Г.А. , Кужина Г.Ш. , Бускунова Г.Г.
Published: February 2023

В настоящей работе приведены результаты флористического анализа растительных сообществ лугов Башкирского Зауралья с участием ресурсного вида Trollius europaeus L. Проанализирована таксономическая структура растительных сообществ. Изучены экологическая структура сообществ и их принадлежность к экологическим группам растений, происхождение видов сообществ, а также ресурсное значение видов сообществ с участием Trollius europaeus.

This paper presents the results of a floristic analysis of plant communities of meadows of the Bashkir Trans-Urals with the participation of the resource species Trollius europaeus L. The taxonomic structure of plant communities is analyzed. The ecological structure of communities and their belonging to ecological groups of plants, the origin of community species, as well as the resource value of community species with the participation of Trollius europaeus have been studied.
MORPHOLOGICAL FEATURES OF SPIRAEA BETULIFOLIA PALL. AND ITS VARIETIES 'TOR' AND 'TOR GOLD' IN THE CONDITIONS OF THE CITY OF MOSCOW
Authors: Крючкова В.А. , Симахин М.В. , Пашутин В.Р. , Горбунов Ю.Н.
Published: February 2023

Спирея березолистная – распространенный декоративный кустарник, используемый в групповых и одиночных посадках. Отличается достаточно высокой зимостойкостью, низкой засухоустойчивостью, устойчивостью к засолению. Сорт ‘Tor’ является отборной формой из сеянцев спиреи березолистной, получен в Швеции, сорт ‘Tor Gold’ – его естественная мутация, отобранная в Нидерландах. Анализ изменчивости морфологических признаков типовой формы и ее сортов, проведенный в одинаковых условиях выращивания, позволил выявить некоторые диагностические признаки. По большинству качественных признаков, за исключением плотности кроны для сортов ‘Tor’ и ‘Tor Gold’ и окраски листовой пластинки сорта ‘Tor Gold’ отличий от типовой формы не обнаружено. Сорта отличаются от типовой формы меньшей высотой, а сорт ‘Tor Gold’ – более мелкими листьями, диаметром соцветия и меньшим числом цветков в соцветии. Существенных отличий, кроме размеров растения и плотности кроны, для сорта ‘Tor’ не обнаружено, сорт ‘Tor Gold’ отличается от типовой формы и сорта ‘Tor’ модификациями количественных признаков, не отличаясь по комплексу качественных, кроме окраски листовой пластинки, что исключает возможность их происхождения в результате межвидовой гибридизации.

Birch-leaved spirea is a common ornamental shrub used in group and single plantings. Differs in rather high winter hardiness, low drought resistance, resistance to salinity. Variety ‘Tor’ is a selective form from seedlings of birch leaf spirea, obtained in Sweden, variety ‘Tor Gold’ is its natural mutation, selected in the Netherlands. An analysis of the variability of morphological characters of the type form and its varieties, carried out under the same growing conditions, made it possible to identify some diagnostic characters. For most qualitative traits, with the exception of the density of the crown for the varieties ‘Tor’ and ‘Tor Gold’ and the color of the leaf blade of the ‘Tor Gold’ variety, no differences from the type form were found. The cultivars differ from the type form in their lower height, while ‘Tor Gold’ cultivar differs in smaller leaves, inflorescence diameter and fewer flowers per inflorescence. No significant differences, except for plant size and crown density, were found for 'Tor' cultivar, 'Tor Gold' cultivar differs from the type form and 'Tor' cultivar by modifications of quantitative traits, not differing in a complex of qualitative characteristics, except for the color of the leaf blade, which excludes the possibility their origin as a result of interspecific hybridization.
GENERALIZATION OF THE SPATIAL ELECTROMECHANICAL MODEL OF THE EXOSKELETON FOR THE CASE OF AN ARBITRARY NUMBER OF LINKS OF VARIABLE LENGTH
Authors: Блинов А.О. , Борисов А.В. , Кончина Л.В. , Маслова К.С.
Published: February 2023

В статье представлены в обобщенном векторно-матричном виде результаты изучения структуры систем дифференциальных уравнений движения для моделей с одним, двумя, тремя звеньями в виде обобщения на случай многозвенной модели экзоскелета, состоящего из произвольного конечного количества звеньев переменной длины, дополненные уравнениями асинхронного электродвигателя.

The article presents in a generalized vector-matrix form the results of studying the structure of systems of differential equations of motion for models with one, two, three links in the form of a generalization for the case of a multi-link exoskeleton model consisting of an arbitrary finite number of links of variable length, supplemented by the equations of an asynchronous electric motor.
A METHOD FOR CONTROL OF THE SPATIAL MOVEMENT OF A LINK OF VARIABLE LENGTH AND ADJUSTABLE RIGIDITY EXOSKELETON WITH A PAYLOAD AND CALCULATION OF ENERGY COSTS
Authors: Блинов А.О. , Борисов А.В. , Кончина Л.В. , Новикова М.А.
Published: February 2023

В статье предложена модель звена экзоскелета переменной длины с управляемой жесткостью. Звено моделирует опорную ногу. В верхней точке звена приложена полезная нагрузка, моделирующая вес корпуса, головы, рук и переносимой ноги. Записаны дифференциальные уравнения движения и уравнение для определения напряженности магнитного поля. Предложен метод управления движением на основе задания кинематических характеристик движения, определены управляющие моменты, сила и напряженность внешнего магнитного поля.

The article proposes a model of an exoskeleton link of variable length with controlled stiffness. The link models the supporting leg. At the top of the link, a payload is applied that simulates the weight of the body, head, arms, and carried leg. The differential equations of motion and the equation for determining the magnetic field strength are written down. A motion control method based on setting the kinematic characteristics of motion is proposed, the control moments, the strength and intensity of the external magnetic field are determined.
MICROORGANISMS – CAUSATIVE AGENTS OF MASTITIS IN CATTLE
Authors: Жаркова Е.К. , Вертипрахов В.Г. , Жевнеров А.В.
Published: February 2023

Воспаление вымени у крупного рогатого скота молочного направления является наиболее распространенной болезнью. Микроорганизмы, принадлежащих к различным систематическим группам, а также продукты микробного синтеза способны приводить к возникновению мастита при проникновении в молочную железу коров. Обилие видов микроорганизмов – патогенов обуславливает необходимость уточнения методов терапии в каждом конкретном случае.

Udder inflammation in dairy cattle is the most common disease. Systematically different Microorganisms belonging to various systematic groups, as well as products of microbial synthesis, can lead to the appearance of mastitis when entering the mammary gland of cows. The abundance of pathogenic microorganism species forces to clarify the methods of therapy in each specific case.
CAUSES AND DEGREE OF DEGRADATION OF AGRICULTURAL LANDS OF TUVA
Authors: Самбуу А.Д. , Оксюлюк А.О. , Дугержаа Ч.Ш.
Published: February 2023

В статье рассматривается оценка трансформации земель сельскохозяйственного назначения Республики Тыва в сравнении их состояния на период с 1965 г. по 2022 г. Выявлено, что особенно сильно деградированы земли сельскохозяйственных угодий степных межгорных котловин. Более возвышенная северо-восточная часть территории Тувы входит в подтаежную зону, поэтому эрозионными процессами затронута незначительно. Наиболее деградированы земли южных и центральных сельскохозяйственных районов с индексом аридности 0.16–0.40, т.е. на сухостепных и полупустынных территориях. Цель работы – изучение причин деградации земель сельскохозяйственного назначения и оценка степени их деградации в Республике Тыва.

The article considers the assessment of the transformation of agricultural lands of the Republic of Tyva in comparison with their condition for the period from 1965 to 2022. It was revealed that the agricultural lands of the steppe intermountain basins are especially severely degraded. The more elevated northeastern part of the territory of Tuva is included in the subtaiga zone, therefore, it is slightly affected by erosion processes. The lands of the southern and central agricultural regions with an aridity index of 0.16–0.40 are the most degraded, i.e. in dry-steppe and semi-desert territories. The purpose of the work is to study the causes of degradation of agricultural lands and assess the degree of their degradation in the Republic of Tyva.
THE EFFECT OF SOME POLLUTANTS ON THE PROPERTIES OF BUILDING MATERIALS
Authors: Шершнева М.В. , Бенза Е.В.
Published: February 2023

В статье рассмотрены проблемы воздействия тяжелых металлов на некоторые свойства строительных материалов. Показана возможность управления механо-физическими свойствами клинкерных минералов, фосфатных вяжущих и пенобетонов различной плотности. Приведены данные по зависимости свойств строительных материалов от доли вводимого загрязнителя.

The article deals with the problems of the impact of heavy metals on some properties of building materials. The possibility of controlling the mechanical and physical properties of clinker minerals, phosphate binders and foam concrete of various densities is shown. Data on the dependence of the properties of building materials on the proportion of the introduced pollutant are presented.
PROSPECTS FOR THE USE OF SOLID MINERAL WASTE FOR REHABILITATION AND LAND RECLAMATION
Authors: Шершнева М.В. , Бенза Е.В. , Лагздина А.С.
Published: February 2023

В статье рассмотрены проблемы санации и рекультивации городских земель. Показана необходимость поиска перспективных и доступных материалов для очистки земель от загрязнений различной природы. Приведены данные по обезвреживающей способности хлоритового щебня по отношению к ионам тяжелых металлов, растворенным нефтепродуктам и биологическим загрязнениям.

The article deals with the problems of sanitation and reclamation of urban lands. The need to search for promising and affordable materials for cleaning land from pollution of various nature is shown. The data on the neutralizing ability of crushed chlorite in relation to heavy metal ions, dissolved oil products and biological contaminants are given.
NATURAL CONDITIONS OF SOIL FORMATION IN UBSUNUR BASIN
Authors: Самбуу А.Д. , Нажик М.К.
Published: February 2023

Территория Убсунурской котловины, где проводились исследования, представляет собой обширную тектоническую котловину с одноименным соленым озером, ограниченную с севера хребтами Танну-Ола, с юга хребтом Хан-Хухей, принадлежащего к системе гор Хангая. Озеро Убсу-Нур входит в Котловину Больших Озер. Убсунурская котловина, находящаяся между двумя различными природными единицами: Алтае-Саянской горной областью и областью опустыненных степей и пустынь бессточных котловин Северной Монголии, характеризуется большим разнообразием форм рельефа, неоднородностью растительного покрова, своеобразием распределения гидротермических факторов и геологической истории. Согласно “Почвенно-географическому районированию СССР” [1], территория исследований относится к Тувинской сухостепной провинции темно-каштановых и каштановых почв. Эта провинция состоит из двух почвенных округов, приуроченных к крупным межгорным относительно пониженным глубоким депрессиям (котловинам), разделенным хребтом Танну-Ола: Центрально-Тувинской или Улуг-Хемской и Убсунурской. Цель работы – изучение природных условий почвообразования в Убсунурской котловине.

The territory of the Ubsunur basin, where the research was conducted, is an extensive tectonic basin with the salt lake of the same name, bounded on the north by the Tannu-Ola ridges, on the south by the Khan-Huhey ridge, belonging to the Hangai mountain system. Lake Ubsu-Nur is part of the Basin of Large Lakes. The Ubsunur basin, located between two different natural units: the Altai-Sayan mountain region and the region of desolate steppes and deserts of the drainless basins of Northern Mongolia, is characterized by a wide variety of relief forms, heterogeneity of vegetation cover, the peculiarity of the distribution of hydrothermal factors and geological history. According to the “Soil-geographical zoning of the USSR” [1], the research area belongs to the Tuva dry-steppe province of dark chestnut and chestnut soils. This province consists of two soil districts confined to large intermountain relatively lowered deep depressions (hollows) separated by the Tannu-Ola ridge: the Central Tuva or Ulug-Khem and Ubsunur. The purpose of the work is to study the natural conditions of soil formation in the Ubsunur basin.
CONDITIONS FOR THE ORIGIN AND FORECAST OF HAIL IN THE EUROPEAN TERRITORY OF RUSSIA
Authors: Асауляк И.Ф. , Белолюбцев А.И. , Обухов М.О.
Published: February 2023

Проведен анализ оправдываемости методов прогноза града на Европейской территории России по методам Н.С. Шишкина, Г.Д. Решетова и радиолокационного зондирования атмосферы.

The analysis of the feasibility of hail forecasting methods in the European territory of Russia using the methods of N.S. Shishkin, G.D. Reshetov and radar sounding of the atmosphere is carried out.
STRUCTURAL CHANGES OF NATURE MANAGEMENT IN THE TERRITORY BAIDARSKAYA VALLEY
Authors: Воробьева Т А. , Горецкая А Г. , Кириллов С.Н. , Слипенчук М.В.
Published: February 2023

В работе проанализированы основные этапы хозяйственного освоения Байдарской долины, повлекшие изменение структуры природопользования в прошлом и начале этого века.

The main stages of the economic development of the Baydarskaya Valley were analyzed, which led to a change in the structure of nature management in the past and early this century.
ANALYSIS AND SYNTHESIS OF STRUCTURES AND MECHANISMS OF THE FIRST SUBFAMILY OF THE FIRST FAMILY
Authors: Вовкотруб В.В. , Савицкий Ю.А. , Терехов В.В.
Published: February 2023

В статье авторами рассмотрены особенности синтеза структур механизмов первого подсемейства первого семейства. Найдены решения, описывающие организацию и структурные формулы цепей нулевой подвижности первого семейства. Авторами приведен полный состав решений для первого подсемейства первого семейства механизмов при τ = 3 и числе подвижных звеньев от 3 до 4. Используя данные приведенные в Таблице 1 можно найти все без исключения схемы механизмов первого подсемейства первого семейства при заданных параметрах. Для этого вначале необходимо вычертить кинематическую схему механизма с виртуальными парами, т.е. парами, на место которых могут быть поставлены пары II, III, IV или V классов согласно полученному решению. Далее на место виртуальных кинематических пар ввести пары определенного класса с конкретным комплексом движений.

In the article, the authors consider the features of the synthesis of structures of mechanisms of the first subfamily of the first family. Solutions describing the organization and structural formulas of zero mobility chains of the first family are found. The authors present a complete set of solutions for the first subfamily of the first family of mechanisms at τ = 3 and the number of moving links from 3 to 4. Using the data given in Table 1, it is possible to find all, without exception, the schemes of mechanisms of the first subfamily of the first family under the given parameters. To do this, it is first necessary to draw a kinematic scheme of the mechanism with virtual pairs, i.e. pairs, in place of which pairs of classes II, III, IV or V can be put according to the solution obtained. Then, in place of virtual kinematic pairs, introduce pairs of a certain class with a specific set of movements.
AVIATION PISTON ENGINES OF RUSSIA AT THE INTERNATIONAL ENGINE BUILDING FORUM (IEBF-2022)
Authors: Кузнецов Г.А. , Мальков А.Д. , Гильмияров М.Р.
Published: February 2023

В статье проведен анализ авиационных поршневых двигателей (АПД) России, представленных на МФД-2022. Отмечено возрождение поршневого двигателестроения и лидирующая роль ЦИАМ в этом процессе. За последние 10 лет в ЦИАМ созданы перспективные образцы АПД, которые могут служить современной платформой для формирования модельного ряда эффективных силовых установок.

The article analyzes the aircraft piston engines (APEs) of Russia, presented at the IEBF-2022. The revival of piston engine building and the leading role of CIAM in this process are noted. Over the past 10 years, CIAM has created promising models of APEs, which can serve as a modern platform for the formation of a model range of efficient power plants.
A COMPLEX AGENT STIMULATING THE GROWTH OF PINE SEEDLINGS BASED ON BACTERIA AND HUMIC SUBSTANCES TO INCREASE THE CARBON DEPOSITING EFFECT IN WOODY PLANTS
Authors: Четверикова Д.В. , Четвериков С.П. , Тимергалин М.Д. , Арасланова Л.Х. , Назаров А.М.
Published: February 2023

Изучено влияние двух ростстимулирующих штаммов Pseudomonas, гуминовых веществ и их композиций на ростовые характеристики саженцев сосны обыкновенной в рамках концепции «ускорение роста саженцев деревьев – подход к сокращению углеродного следа». Обе бактерии усиливали рост побегов и корней саженцев сосны, что объяснялось их способностью синтезировать ауксины. Штамм P. protegens DA1.2 оказался более эффективным, чем Pseudomonas sp. 4CH. В варианте сочетания штамма бактерий P. protegens DA1.2 и гуминовых веществ было обнаружено увеличение длины стволиков и корней на 52,7% и 69,7%, соответственно, относительно контрольного варианта без обработки.

The influence of two growth-stimulating strains of Pseudomonas, humic substances and their compositions on the growth characteristics of Scots pine seedlings was studied within the concept of «acceleration of the growth of tree seedlings – an approach to reducing the carbon footprint». Both bacteria enhanced the growth of shoots and roots of pine seedling, which was explained by the ability to synthesize auxins. The P. protegens DA1.2 strain proved to be more effective than Pseudomonas sp. 4CH. In the combination of the bacterial strain P. protegens DA1.2 and humic substances, an increase in the length of shoots and roots by 52,7% and 69,7%, respectively, was found relative to the control variant without treatment.
К ПРОБЛЕМАМ ВЗАИМОДЕЙСТВИЯ УНИВЕРСИТЕТОВ В РАМКАХ ПРОВЕДЕНИЯ СОВМЕСТНОГО МЕЖДУНАРОДНОГО ПРОЕКТА
Authors: Бубнова Ю.В.
Published: February 2023

Статья посвящена проблемам, связанным с организацией, взаимодействием вузов и проведением совместного международного проекта. Цель данной работы – раскрыть преимущества и недостатки данного способа обучения в вузах и наметить пути ешения возникающих проблем в ходе его применения.
KAWASAN AGROWISATA DI KABUPATEN KAYONG UTARA DENGAN PENDEKATAN ARSITEKTUR BIOKLIMATIK
Authors: Wati Nisma , Putro Jawas Dwijo , Alhamdani Muhammad Ridha
Published: February 2023

The development of tourism areas is one of the high priority sectors in Indonesia. One of the tourism sectors that has the potential to be developed in Indonesia is agrotourism. Sukadana is one of the sub-districts as well as the capital of North Kayong Regency which has many tourist destinations in the form of beaches, mountains and other natural beauty such as paoh hills, mangrove forests, etc. In addition to the tourism sector, Sukadana is also very famous for its durian products. Durian is one of the many varieties of fruits found in Sukadana District. However, in recent years there has been a decline in durian fruit sales. This is due to the pandemic period which sometimes limits the access of people outside the Sukadana District to visit. With this problem, the idea was created to create an agro-tourism area in North Kayong Regency that can support the distribution of fruits both during the pandemic and during normal times. The design of this agro-tourism area uses a bioclimatic architectural approach that pays attention to the relationship between architectural forms and their environment, especially in matters relating to the climate of the area. This agro-tourism area applies the concept of a Tourism and Education Village (Tourism And Education Village) where in addition to traveling, visitors can also get education related to agriculture and plantations. With the existence of this agro-tourism area, it is expected to affect the rate of economic growth in North Kayong Regency, especially the people of Sukadana District.
METODE PENGUKURAN PADA EVALUASI KONDISI BANGUNAN BERSEJARAH TERHADAP KEMIRINGAN ATAU PERBEDAAN ELEVASI (STUDI KASUS MASJID JAMI KESULTANAN SAMBAS)
Authors: Wijaya Vita Ilona , Zain Zairin , Purnomo Yudi
Published: February 2023

According to the Law of the Republic of Indonesia Number 11 of 2010, the forms of cultural heritage are very diverse and one of them is in the form of buildings. Sambas is one of the areas that have a long-standing cultural heritage building, namely the Jami Mosque of the Sambas Sultanate. This building has been standing since 1727 and is one of the witnesses to the history of the sultanate government in Sambas in the past. The age of the mosque is now more than 100 years and attention to the condition of the building is needed, especially to the slope or difference in elevation. Therefore, this study was conducted to evaluate the condition of the historic building of the Jami Mosque of the Sultanate of Sambas on the slope or difference in elevation. This research was conducted by quantitative descriptive with field observation data collection methods and literature review. Field observations were carried out through manual measurements. The measurement data will be processed to evaluate its condition. Measurements will be carried out on one of the rooms in the Jami Mosque of the Sambas Sultanate, namely the Storage Room. From the results of measurements of the floor of the Storage Room, the results showed that there was a deflection of the floor at one of the measuring points. This can indicate a slope, so further inspection is needed to determine the factors causing the slope, as well as recommendations for improvement to minimize the risk of the slope getting worse.
Opportunities for improving the processes of preparing legal acts by public authorities based on the process mining
Authors: Vasilieva E. V. , Dolganova O. I.
Published: February 2023

The processes of creating legal acts must meet such criteria as transparency, controllability, compliance with regulations. However, currently the procedures are extremely bureaucratic, pre-planned and go through many instances during the preparation, approval and signing. Of course, most of these processes are necessary, time-tested and legally fixed. At the same time, there are operations that require optimisation, including due to their automation or robotisation. To identify them and ensure that the procedure meet the changing needs of the state, it is important to create conditions for continuous monitoring, timely identification and operational adaptation and optimisation of the rule-making activities of the authorities. In this regard, the issue of applying contemporary technologies and approaches to analysis and the formation of recommendations for improving proactive processes seems extremely relevant. The purpose of this study is to examine the currend specifics of the preparation of the legal acts by the federal executive authorities and to identify areas for this normative documents’ improvement based on the process mining. The research methods used were a literature review and the Russian legal framework analysis, a questionnaire survey and process modelling. The authors analyse how draft legal documents (government and presidential acts, federal laws) are developed in the Russian Federation. They demonstrate the need for a transition to smart management. Its principles will ensure efficiency and flexibility in the preparation of normative legal acts. The metrics for monitoring and controlling the execution of the relevant instructions are formulated and the prospects for the development of their information support as a result of the implementation of process mining technologies are highlighted.
Particle Size and Pore Size Selection on Ordered Mesoporous Silica
Authors: Li Tianyu
Published: February 2023

Controlling both particle size and pore size is critical when using mesoporous silica for fundamental studies. Pore size can be adjusted by modifying the reaction conditions during synthesis, but achieving a narrow particle size selection can be challenging. However, by allowing mesoporous silica to sediment in water, we can take advantage of the fact that particles of different sizes settle at different speeds in liquid. This approach enables us to obtain mesoporous silica particles with the exact pore size but different particle sizes or particles with varying pore sizes but the same particle size. This fine-tuning of particle size and pore size ensures precise control of the properties of mesoporous silica and is essential for many applications in various fields.
Fractional-Electron and Transition-Potential Methods for Core-to-Valence Excitation Energies Using Density Functional Theory
Authors: Jana Subrata , Herbert John
Published: February 2023

Methods for computing x-ray absorption spectroscopy at the self-consistent field level are examined, based on a constrained core hole (possibly containing a fractional electron), and in some cases promoting an electron or a fraction of an electron into the virtual space. These methods are based on Slater's transition concept and its generalizations (including the transition-potential method), wherein core-to-valence excitation energies are determined using Kohn-Sham orbital energies. Variants of this idea are systematically tested, revealing a best-case accuracy of 0.3-0.4 eV with respect to experiment for K-edge excitation energies, although errors are much larger in many cases. For higher-lying near-edge transitions, even the best of these methods affords errors of ~2 eV. Absolute errors are reduced below 1 eV by introducing an empirical shift based on a charge-neutral transition-potential method, in conjunction with functionals such as SCAN, SCAN0, or B3LYP. This procedure affords an entire excitation spectrum from a single fractional-electron calculation, at the cost of ground-state density functional theory and without the need for state-by-state calculations. This shifted transition-potential approach may be especially useful for simulating transient spectroscopies or in complex systems where excited-state Kohn-Sham calculations are challenging,
Orbitrap mass spectrometry and high-field asymmetric waveform ion mobility spectrometry (FAIMS) enable the in-depth analysis of human serum proteoforms
Authors: Kline Jake , Belford Michael , Boeser Cornelia , Huguet Romain , Fellers Ryan , Greer Joseph , Greer Sylvester , Horn David , Durbin Kenneth , Dunyach Jean-Jacques , Ahsan Nagib , Fornelli Luca
Published: February 2023

Blood serum and plasma are arguably the most commonly analyzed clinical samples, with dozens of proteins serving as validated biomarkers for various human diseases. Top-down proteomics may provide additional insights into disease etiopathogenesis since this approach focuses on protein forms, or proteoforms, originally circulating in blood, potentially providing access to information about relevant post-translational modifications, truncation, single amino acid substitutions and many other sources of protein variation. However, the vast majority of proteomic studies on serum and plasma are carried out using peptide-centric, bottom-up approaches which cannot recapitulate the original proteoform content of samples. Lengthy sample preparation and the need for extensive prefractionation to mitigate proteoform dynamic range issues are likely factors preventing clinical laboratories from routinely performing top-down experiments. In this study, we describe a straightforward protocol for intact proteoform sample preparation based on depletion of albumin and immunoglobulins followed by simplified fractionation of remaining serum proteins via polyacrylamide gel electrophoresis. After molecular weight-based fractionation, we supplemented the traditional liquid chromatography tandem mass spectrometry (LC-MS2) data acquisition with high-field asymmetric waveform ion mobility spectrometry (FAIMS), which served as an additional separation dimension to further simplify serum proteoforms mixtures. This LC-FAIMS-MS2 method led to the identification of over 1,000 serum proteoforms <30 kDa using a reduced number of experiments, more than doubling the number of proteoforms identified in previous studies.
Silver(I)-Catalyzed Synthesis of Cuneanes from Cubanes and their Investigation as Isosteres
Authors: Smith Elliot , O'Brien Luke , Jones Kieran , Argent Stephen , Salome Christophe , Lefebvre Quentin , Valery Alain , Newton Graham , Lam Hon Wai
Published: February 2023

Bridged or caged polycyclic hydrocarbons have rigid structures that project substituents into precise regions of 3D space, making them attractive as linking groups in materials science and as building blocks for medicinal chemistry. The efficient synthesis of new or underexplored classes of such compounds is therefore an important objective. Herein, we describe the silver(I)-catalyzed rearrangement of 1,4-disubstituted cubanes to cuneanes, which are strained hydrocarbons that have not received much attention from the synthetic community. The synthesis of 2,6-disubstitued or 1,3-disubstituted cuneanes can be achieved with high regioselectivities, with the regioselectivity being dependent on the electronic character of the cubane substituents. A preliminary assessment of cuneanes as scaffolds for medicinal chemistry was also performed, which suggests cuneanes could serve as isosteric replacements of trans-1,4-disubstituted cyclohexanes and 1,3-disubstituted benzenes.
Reactivity of Alloxydim: Force and Reaction Electronic flux profiles
Authors: Villaverde Juan José , Sandn-España Pilar , Alonso-Prados José Luis , Alcami Manuel , lamsabhi Al Mokhtar
Published: February 2023

The Reaction force profile and the electronic reaction flux concepts were explored for Alloxydim and some of its derivatives at B3LYP/6-311G(d,p) level of theory. The exploration was achieved by varying the dihedral angle located nearby the most reactive region. The main objective is to understand the response of the oxime group against this perturbation together with highlighting the intrinsic structural and the electronic reorganization. The results show that the rotation of the dihedral angle triggers the alloxydim to go through three transition states. The first step of the transformation begins by the rupture of the hydrogen bond and is characterized by a pronounced structural reorganization. To return to the same structure in the last step of the process the electronic reorganization are more important. In between, N-O bond goes through different state of the reinforcement and weakening showing the ideal conformer where the oxime fragment might be dissociated.
Urban Housing & Community: A Case for Collective City Living at High-Density
Authors:   , Cook Ashleigh
Published: February 2023

Aotearoa New Zealand is experiencing a housing crisis. The cost of housing is rising, and supply cannot keep up with demand, leaving many people in desperate need of better housing options within our city centres. A commonly proposed solution is to provide urban housing in the form of high-density apartments. This is a housing typology that many New Zealanders are resistant to and begs an innovative response to the question of liveability in high-density housing in New Zealand.

This thesis asks, ‘How can shared space and facilities in dense urban housing environments improve liveability?’This research highlights two opportunities for urban housing: firstly, to improve liveability through provision of desirable, community focused high-density apartments; secondly, to address the urgent need for accessible, diverse, alternative housing models in Aotearoa. Following an iterative design-led research approach, this thesis proposes highdensity collective housing as an alternative model to improve apartment liveability. The design results in site-specific development of a high-density mixed-use housing project on Wellington’s waterfront.

The thesis concludes with five key findings. 1. Sharing space and facilities improves urban liveability. They provide opportunities for social connection, inclusivity, mutual support, safety, affordability, and housing stability, among other benefits. 2. Diversity provides choice and results in more desirable urban housing. A variety of unit designs and tenure models are necessary appeal to potential occupants. 3. Mixed-uses help to integrate communities. Providing a variety of public mixed-use spaces and activities allows for the wider neighbourhood community to integrate with the collective housing community in neutral territory. 4. Housing liveability needs to reflect Aotearoa’s housing values. The qualities of safety, warmth, natural light, spaciousness, and access to the outdoors are valued highest amongst New Zealanders (Yeoman & Akehurst, 2015). 5. Privacy gradients improve liveability. When there is an understanding of space as either private or shared, and an obvious boundary between each level of privacy, the liveability of collective housing is improved.
Tejidos residenciales en Guayaquil: indicadores urbanos relativos a la compacidad y la funcionalidad
Authors: Pérez de Murzi Teresa , Orejuela Gaudy
Published: February 2023

Las Zonas Pascuales y Norte representan el avance más reciente de la huella urbana de Guayaquil en la frontera norte del cantón homónimo. Allí conviven diversas formas residenciales que van haciendo ciudad, a su propio ritmo y con sus propias lógicas. Este artículo tiene como objetivo presentar un análisis comparativo de tejidos residenciales a partir de la cualificación de su morfología y el uso de indicadores relacionados con la compacidad y la funcionalidad, uno de los objetivos básicos del urbanismo sostenible. Los tejidos residenciales fueron clasificados inicialmente por su origen, tipo de promoción y permeabilidad. El análisis, a través de un sistema de comparación homogéneo y utilización de parámetros cuantitativos asociados a la compacidad y la funcionalidad, permite visualizar el comportamiento, a escala barrial, de esta urbe ecuatoriana y establecer un esquema metodológico susceptible de integrarse a los diagnósticos con fines de planificación. Los resultados apuntan a importantes carencias en estos contextos fundamentales de la vida local, indiferentemente de sus orígenes y de los actores vinculados en su producción: déficit de espacios públicos, densidades inadecuadas y mezcla de usos y funciones urbanas, derivada principalmente de la improvisación.
Contribuciones de space syntax en la investigación sobre la historia morfológica y social del espacio urbano: los casos de Morella y Montblanc
Authors: Beltran Borràs Júlia
Published: February 2023

El objetivo principal de este artículo es explorar las aportaciones de space syntax en la investigación histórica sobre las relaciones interactivas entre la forma urbana y el uso social del espacio. Desarrollando este tema, el articulo explora la estructura configuracional de los recintos amurallados de Morella y Montblanc, poniendo especial atención en los portales de acceso. La teoría y métodos de space syntax se han aplicado sobre el trazado urbano actual y sobre planos antiguos de ambas ciudades, y la información analítica extraída se ha contrastado con observaciones etnográficas y con documentos históricos, para proporcionar contextos y resolver ambigüedades. Los resultados del análisis en Morella muestran que, cuando un portal de la ciudad desaparece, se modifica completamente la cultura espacial del lugar; sin embargo, la historia social queda inscrita en la historia morfológica. En el caso de Montblanc, el estudio de la evolución de la forma urbana aporta nuevos datos sobre la significación cultural de los portales de la muralla en la ciudad del pasado. Tal como concluye este trabajo el space syntax está haciendo contribuciones significativas a la investigación sobre la historia morfológica y la historia social del espacio urbano, que pueden tener repercusión directa en la toma de decisiones de diseño en la recuperación y/o gestión del patrimonio.
Análisis espaciotemporal del comercio: dinámicas pre y post-COVID en Gros, San Sebastián
Authors: Berra-Sandín Mikel
Published: February 2023

La caída de la actividad comercial que viene sucediendo en la última década ha sido recientemente acentuada por el COVID, con efectos sobre la habitabilidad de las ciudades y el espacio público. El presente trabajo analiza las actividades en planta baja en el barrio de Gros, en San Sebastián, España, observando tanto su evolución temporal como su distribución espacial. El estudio realiza dos tomas in situ de datos geolocalizados en enero y agosto de 2020, inmediatamente antes y después del confinamiento por COVID en España. A partir de ellos, analiza la distribución y evolución de los espacios en planta baja dedicados a actividades de concurrencia pública. El estudio concluye que las actividades han sufrido una caída del 1,8% en el periodo analizado, y que aquellas actividades sitas en calles peatonalizadas o con menos carriles han sufrido menos cierres. A su vez, el trabajo muestra qué esfuerzos requiere la colección de datos in situ que puedan ayudar a guiar políticas urbanas.
JAVIER MONCLÚS, BORJA RUÍZ-APILÁNIZ (EDS.) - Forma Urbana y Desarrollo Sostenible
Authors: Cuchí Burgos Albert
Published: February 2023

Javier Monclús, Borja Ruíz-Apilániz (eds.)Forma Urbana y Desarrollo SostenibleNúmero monográfico 2022 de la revista Ciudad y Territorio Estudios Territoriales.Ministerio de Transportes, Movilidad y Agenda Urbana. Madrid, Vol. LIV, 2022. Idioma: español.Disponible en https://recyt.fecyt.es/index.php/CyTET/indexISSN(P): 1133-4762ISSN(E): 2659-3254DOI: 10.37230/CyTET.2022.M22
JORGE GALLEGO SÁNCHEZ-TORIJA - Máquinas de habitar. Hacer arquitectura con las instalaciones
Authors: Gálvez Huerta Miguel Angel
Published: February 2023

Jorge Gallego Sánchez-TorijaMáquinas de habitar. Hacer arquitectura con las instalacionesMadrid: Ediciones Asimétricas, 2022. 165 pp. Tapa blanda. Idioma: español. 19,00 €ISBN: 978-84-19050-11-3
JORGE PÉREZ JARAMILLO - Medellín. Urbanismo y sociedad
Authors: Garrido Ginés
Published: February 2023

Jorge Pérez JaramilloMedellín. Urbanismo y sociedadMadrid: Turner, 2019. 256 pp. Tapa blanda. Idioma: español. 22,00 €ISBN: 9-788417-866099
EDUARD CALLÍS FREIXAS - Arquitectura de los pantanos en España
Authors: Carbajal-Ballell Nicolás
Published: February 2023

Eduard Callís FreixasArquitectura de los pantanos en EspañaSevilla: Universidad de Sevilla e Instituto Universitario de Arquitectura y Ciencias de la Construcción, 2021. 276 pp. Tapa blanda. Idioma: español. 19,00 €ISBN: 978-84-472-2310-7
MIGUEL GUITART - Behind Architectural Filters. Phenomena of Interference
Authors: Labarta Aizpún Carlos
Published: February 2023

Miguel GuitartBehind Architectural Filters. Phenomena of InterferenceNew York: Routledge, 2022. 302 pp. Tapa dura. Idioma: inglés. 36,26 €ISBN: 978-1-032-07748-2
ROSER MARTÍNEZ-RAMOS E IRUELA - La Gran Vía de Colón de Granada. Reconstrucción del proyecto y obra de una cala urbana 1891-1931
Authors: Pérez Escolano Víctor
Published: February 2023

Roser Martínez-Ramos E IruelaLa Gran Vía de Colón de Granada. Reconstrucción del proyecto y obra de una cala urbana 1891-1931Granada: Editorial Universidad de Granada / Diputación de Granada, 2021. 320 pp. Tapa blanda. Idioma: español. 23,75 €ISBN: 9788478077014