bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and testing of the method and algorithm for forming coalitions of experts in the study of the functioning of communication networks
Authors:   Voronezh Institute of the Ministry of Internal Affairs of Russia, Popov Aleksey V.
Published: June 2023

The issues related to the use of expert assessment methods in order to increase the optimality and objectivity of developed management decisions are considered. The expediency of involving experts is formulated when a collegial management decision is necessary. The basic stages of the research related to the application of the expert assessment method are given. The relevance of the chosen topic is justified by the need to develop effective methods and algorithms aimed at automating the processes of analysis and processing of data obtained during the expert survey, as well as summarizing its results. The aim of the study is to develop and test an algorithm for finding coordinated groups (coalitions) of experts, as well as a method that makes it necessary to work out the final decision on the results of the expert survey. The proposed algorithm for finding coalitions is based on the application of the mathematical apparatus of the theory of sets and algebra of relations; it uses a strict criterion in their formation and replenishment of coalitions, but does not exclude the belonging of experts to several coalitions, which provides a high informative value of the results of expert assessment. The method includes the calculation of weighting coefficients assigned to the formed coalitions taking into account the degrees of experts' membership in them. The resulting decision is formed on the basis of the data obtained by the coalition, which has the maximum dimensionality and the required degree of consistency. The developed method and algorithm were tested on the results of an expert survey for determining the degrees of significance of the processes implemented in communication networks. As a result, coalitions of experts who agreed with each other were formed, as well as the experts, whose opinions are more deviated from the rest, were identified. The coherence of the coalitions is evaluated using the concordance coefficient, and the final decision is formed on the basis of the method of average arithmetic ranks assigned to the studied processes of functioning of communication networks by the experts belonging to the largest coalition.
Borsa İstanbul şirketlerinde karbon emisyonu ve temerrüt riski ilişkisi
Authors: ECE ÇOKMUTLU Meltem , ÖZEN Selin
Published: June 2023

Şirketler faaliyetlerini gerçekleştirirken ortaya çıkan en önemli sera gazlarından birisi de karbondur. Karbon emisyonları küresel ısınma ve iklim değişikliğine olan etkisi nedeni ile emisyonunun azaltımına ilişkin pek çok düzenlemenin yapıldığı bir sera gazıdır. Gerek bu düzenlemeler gerekse çevresel sürdürülebilirlik nedeni ile günümüz şirketleri karbon emisyonlarını ölçmekte, açıklamakta ve emisyonların azaltımına ilişkin birçok faaliyet gerçekleştirmektedir. Bu çalışmada Borsa İstanbul’da faaliyet gösteren şirketlerin karbon emisyonu ve temerrüt riski arasında bir ilişkinin olup olmadığı eğer bir ilişki var ise bu ilişkinin şirketin temerrüt riski üzerindeki etkisinin tespit edilmesi amaçlanmıştır. Bu amaçla şirketlerin toplam karbon emisyonları bağımlı değişken olarak belirlenmiş ve Merton modeli ile hesaplanan temerrüde olan uzaklık (DD) değişkeni ile regresyon analizine tabi tutulmuştur. Analizde varlıkların getirisi, kaldıraç ve şirket büyüklüğü kontrol değişkenleri olarak belirlenmiştir. Analiz sonuçlarında karbon emisyonlarının temerrüt riski üzerinde anlamlı bir etkisi olduğu görülmüştür. Şirketlerin regresyon katsayılarına bakıldığında karbon emisyonu arttıkça temerrüt riski artmaktadır. Kontrol değişkenleri ile temerrüt riski arasında da anlamlı ilişkiler bulunmuştur. Karbon emisyonlarının temerrüt üzerindeki anlamlı etkisi nedeni ile işletme kararlarında karbon yönetiminin ve azaltımının da dikkate alınması gerektiği görülmektedir.
Çok Büyük ve Çok Küçük Sayıların Bilimsel Gösterimi ile İlgili Kavram Yanılgıları Nelerdir?
Authors: HACISALİHOĞLU KARADENİZ Mihriban , ÇALIŞKAN Yasemin
Published: June 2023

Bu çalışma, nitel bir metodoloji izleyen durum çalışması yöntemi kullanılmıştır. Çalışma, 8. sınıf öğrencilerinin çok büyük ve çok küçük sayıların (ÇBÇKS) bilimsel gösterimi kavramına ilişkin olası kavram yanılgılarını ortaya çıkarmayı amaçlamaktadır. Araştırmacılar tarafından çalışmanın amacına uygun olarak “Bilimsel Gösterim Kavram Yanılgıları Tanı Testi” hazırlanarak Orta Karadeniz Bölgesinde bulunan bir ortaokulda öğrenim gören 8.sınıf öğrencileri arasından rastlantısal örnekleme yoluyla seçilen 40 öğrenciye uygulanmıştır. Elde edilen verilerin yorumlanmasında betimsel istatistik yöntemi kullanılmıştır. Öğrencilerin sahip oldukları kavram yanılgıları, türlerine göre frekans değerleri (f) belirlenerek araştırmacılar tarafından yorumlanmıştır. Öğrencilerin sahip oldukları yanılgılar; kavram yanılgısı türleri bağlamında incelenmiştir. Çalışma sonucunda, öğrencilerin en çok “aşırı özelleme” ve en az “aşırı genelleme” türlerinde kavram yanılgılarına sahip oldukları ortaya çıkmıştır. Mevcut çalışmada elde edilen önemli sonuçlardan biri ise, öğrencilerin çok büyük ve çok küçük sayıları bilimsel gösterim ile ifade etme konusunun ön öğrenmesi niteliğinde olan bir sayıyı 10’un farklı tam sayı kuvvetlerini kullanarak ifade etmede yaşadıkları işlemsel zorluklardan ötürü cevaplarını bilimsel gösterim ile ifade edemedikleri tespit edilmiştir.
Anxa1 Immunostaining v1
Authors: not provided connor.davidson
Published: June 2023

Protocol for perfusion, slicing, and immunostaining for Anxa1 in the striatum.
Quantifying Synaptic Colocalizations with SynBot (Manual Thresholding) v1
Authors: T Savage Justin
Published: June 2023

Protocol for quantifying synapse numbers using the manual thresholding method in SynBot.
Quantifying Synaptic Colocalizations with SynBot (ilastik Thresholding) v1
Authors: T Savage Justin
Published: June 2023

Protocol for quantifying synapse numbers using the ilastik thresholding method in SynBot.
Clinical characteristics of different forms of myotonic dystrophy type 1
Authors: Erokhina E. K. , Melnik E. A. , Vlodavets D. V.
Published: June 2023

Myotonic dystrophy type 1 (DM1) is one of the most common neuromuscular diseases with an autosomal dominant type of inheritance associated with expansion in the DMPK gene. A distinctive feature of the disease is the presence of muscle symptoms and multisystemic. Depending on the age of onset and the number of CTG repeats, there are congenital, infantile, juvenile, classic (adult) form and a form with a late onset. Each form is characterized by its own features of the onset, course of the disease, heterogeneity of clinical manifestations, which makes it difficult to make a timely diagnosis. Increasing the awareness of physicians of all specialties about the nature of the course of various forms will make it possible to diagnose MD1 at an earlier stage, improve the prognosis and quality of life of patients. The article provides a literature review that demonstrates the spectrum of clinical manifestations in various forms of MD1.
CTNNB1 syndrome (CTNNB1-NDD) in a child with cerebral palsy: a case report
Authors: Golosnaya G. S. , Ermolenko N. A. , Krasnorutskaya O. N. , Efimova V. L. , Larionova T. A. , Tysyachina M. D.
Published: June 2023

In this article, we report a case of CTNNB1 syndrome (CTNNB1-NDD) in a child with cerebral palsy and also provide a literature review on the problem. CTNNB1 syndrome is an exceedingly rare and poorly studied disorder, which makes it particularly interesting due the difficulties associated with its diagnosis and description of the disease phenotype, as well as highly polymorphic clinical manifestations. Verification of the diagnosis is important to determine the prognosis of a child with cerebral palsy and visual impairment, as well as for reproductive planning in the family.
Endoscopic differential diagnosis of the gastritis-like form of primary non-Hodgkin’s lymphomas and neuroendocrine tumors of the stomach
Authors: Lozovaya V. V. , Malikhova O. A. , Tumanyan A. O. , Malikhov A. G. , Gusarova O. A.
Published: June 2023

Background. The gastritis-like form of primary non-Hodgkin’s lymphomas (NHL) of the stomach is the rarest macroscopic variant of malignant neoplasms of the stomach, endoscopically resembling inflammatory changes in the mucous membrane and, in single observations, polypoid and flatly elevated forms of neuroendocrine tumors (NET) of the stomach. Despite the great experience gained in the diagnosis and treatment of primary NHL of the stomach and NET of the stomach, in clinical practice there are examples that cause difficulties in the correct interpretation of the endoscopic picture and the timely diagnosis.

Aims. To analyze the data of a comprehensive endoscopic examination of patients with diagnoses of a gastritis-like form of primary NHL and NET of the stomach, and to identify the main differentially significant endoscopic criteria characteristic of each individual type of neoplasia.

Materials and methods. In a prospective study conducted at the FSBI “N.N. Blokhin national medical Research Center of Oncology” of the ministry of Health of Russia in the period from 2017 to 2022, data from endoscopic and morphological studies of 69 patients with gastritis-like malignancies were analyzed. All patients underwent a comprehensive endoscopic examination of the upper gastrointestinal tract – esophagogastroduodenoscopy using all clarifying examination methods (narrow-spectrum mode, examination in magnification mode, a combination of narrow-spectrum examination with magnification mode), accompanied by the taking of biopsy material for the purpose of morphological verification of the diagnosis, and endosonographic study.

Results. According to the results of a morphological study, the diagnosis of primary NHL of the stomach was confirmed in 38 patients (55.1 %), NET of the stomach – in 31 patients (44.9 %). A change in diagnosis based on the results of a morphological study occurred in 3 (4.3 %) of 69 (100 %) patients. The sensitivity and diagnostic accuracy of complex endoscopic examination were higher compared to endoscopic examination in white light mode, and amounted to 92.11, 95.65 and 13.16 %, 52.17 %, respectively.

Conclusion. for a correct assessment of the endoscopic picture, it is necessary to conduct a comprehensive endoscopic examination using all clarifying diagnostic methods, which shows greater sensitivity and specificity compared to examination in white light mode.
Surgical aspects of stoma formation in oncology. Literature review
Authors: Gorbunova A. S. , Kuzmichev D. V. , Mamedli Z. Z. , Aniskin A. A. , Polinovsky A. V. , Aleksantsev D. V. , Korshak A. V.
Published: June 2023

The formation of intestinal stoma is performed during routine and emergency operations. This review provides a brief historical overview of the main stages of development of methods colo- and ileostomy. The article presents indications, as well as possible complications that may happen during operative treatment. It is occurred that there is little evidentiary material of colo- or ileostomy in evaluating complications that are associated with the various surgical methods of intestinal stoma formation. The purpose of this review is to summarize the current data on stoma formation and determine the method to use.
THE HISTORY OF THE POLISH-UKRAINIAN BORDERLAND AS AN IMPERATIVE FOR THE CREATIVITY OF THE LITERARY GROUP “ZIEWONIA”
Authors:   Lesya Ukrainka Volyn National University, Sukhareva Svitlana
Published: June 2023

The article highlights the historical motives and inspirations of the literary group “Ziewonia”. Attention is drawn to the influence of the historical era (the period of the November Uprising of the Poles and being under Russian oppression), as well as previous milestones in Polish and Ukrainian history, which were signposts to national liberation. The peculiarities of the development of Ukrainophilism within the general Slavophilism of the first half of the 19th century are taken into account. The place of the scientific concept of Zorian Dołęga-Chodakowski on the transformation of the historical approach to the reception of Slavic literature in general, and Polish and Ukrainian in particular, is determined. In addition to the influence of famous historians, it is also worth highlighting the extraordinary role of the Society of Friends of Science in Lviv. It was from there that ideas about the transformation of historical models came in order to revive the people’s struggle and patriotic sentiments in society. Along with chronicle historicism and Walterscottism, the writers of the “Ziewonia” group in their works highlight the principles of folk historicism, which is largely based on Ukrainian folklore. Song folk images and plots, historical events from Dum are the basis of most of the poetic works of representatives of the “Ziewonia” group. Some of them have clearly expressed anti-Ottoman motives. Thus, Seweryn Goszczyński’s work “Kościelisko” was written in the spirit of folk historicism, as it depicts the struggle of the inhabitants of the Carpathian region against the Tatar army. The presence of a common enemy among the Ukrainian and Polish peoples from previous centuries is transferred to the first half of the 19th century, when such an enemy was the Russian Empire and other imperialist conquering states. Therefore, inspirations of national liberation can be found everywhere in the poetry, prose and drama of “Ziewonia”. The key in historical inspiration was the image of a folk hero or a Cossack. Slavophilic writers successfully put into practice the program principle of “Ziewonia” dedicated to history, in particular literary and critical reflections on the place of Galician writing.
Adaboost CNN with Horse Herd Optimization Algorithm to Forecast the Rice Crop Yield
Authors: Chandraprabha M. , Dhanaraj Rajesh Kumar
Published: June 2023

Over three billion people use rice every day, and it occupies about 12% of the nation's arable land. Since, due to the growing population and the latest climate change projections, it is critical for governments and planners to obtain timely and accurate rice yield estimates. The proposed work develops a rice crop yield forecasting model based on soil nutrients. Soil nutrients and crop production statistics are taken as an input for the proposed method. In ensemble learning, there are three categories, they are Boosting, Bagging and Stacking. In the proposed method, Boosting technique called Adaboost with Convolutional Neural Network is used to achieve the High accuracy by converting weak classifiers to strong classifiers. Adaptive data cleaning and imputation using frequent values are used as pre-processing approaches in the projected technique. A novel technique known as Convolutional neural network with adaptive boosting (Adaboost) technique is projected and can precisely handle more imbalanced datasets. The data weights are initialized; also the initial CNN is trained utilizing original weights of data. The weights of the second CNN are then modified utilizing the first CNN. These actions will be performed sequentially for all weak classifiers. An optimization algorithm called Horse Herd (HOA) is passed down in the proposed technique to find the optimal weights of the links in the classifier. The proposed method attains 95% accuracy, 87% precision, 85% recall, 5% error, 96% specificity, 87% F1-Score, 97% NPV and 12% FNR value.Thus the designed model as predicted the crop yield prediction in the effective manner.
Abstractive Summarization with Efficient Transformer Based Approach
Authors: Karnik Madhuri P. , Kodavade D.V.
Published: June 2023

One of the most significant research areas is how to make a document smaller while keeping its essential information because of the rapid proliferation of online data. This information must be summarized in order to recover meaningful knowledge in an acceptable time. Text summarization is what it's called. Extractive and abstractive text summarization are the two types of summarization. In current years, the arena of abstractive text summarization has become increasingly popular. Abstractive Text Summarization (ATS) aims to extract the most vital content from a text corpus and condense it into a shorter text while maintaining its meaning and semantic and grammatical accuracy. Deep learning architectures have entered a new phase in natural language processing (NLP). Many studies have demonstrated the competitive performance of innovative architectures including recurrent neural network (RNN), Attention Mechanism and LSTM among others. Transformer, a recently presented model, relies on the attention process. In this paper, abstractive text summarization is accomplished using a basic Transformer model, a Transformer with a pointer generation network (PGN) and coverage mechanism, a Fastformer architecture and Fastformer with pointer generation network (PGN) and coverage mechanism. We compare these architectures after careful and thorough hyperparameter adjustment. In the experiment the standard CNN/DM dataset is used to test these architectures on the job of abstractive summarization.
A Hybrid Convolutional Network and Long Short-Term Memory (HBCNLS) model for Sentiment Analysis on Movie Reviews
Authors: Dubey Gaurav , Khera Richa , Grover Ashish , Kaur Amandeep , Goyal Abhishek , Rajkumar Rajkumar , Khatter Harsh , Srivastava Somya
Published: June 2023

This paper proposes a hybrid model (HBCNLS) for sentiment analysis that combines the strengths of multiple machine learning approaches. The model consists of a convolutional neural network (CNN) for feature extraction, a long short-term memory (LSTM) network for capturing sequential dependencies, and a fully connected layer for classification on movie review dataset. We evaluate the performance of the HBCNLS on the IMDb movie review dataset and compare it to other state-of-the-art models, including BERT. Our results show that the hybrid model outperforms the other models in terms of accuracy, precision, and recall, demonstrating the effectiveness of the hybrid approach. The research work also compares the performance of BERT, a pre-trained transformer model, with long short-term memory (LSTM) networks and convolutional neural networks (CNNs) for the task of sentiment analysis on a movie review dataset..
ADVERSE CHILDHOOD EXPERIENCES IN PSYCHOACTIVE SUBSTANCE USE DISORDERS: A STRUCTURED LITERATURE REVIEW
Authors: Bebere Sabīne , Vrubļevska Jeļena
Published: June 2023

Adverse childhood experiences include psychological, physical, and sexual forms of abuse, as well as dysfunction in the home, including substance abuse among family members, and mental health problems in the family. These experiences are among the most intense and frequent sources of stress that children can experience early in life, and they also increase their risk of various behavioural disorders and substance abuse. Aim: The study aimed to investigate the prevalence and potential impact of childhood adverse experiences in connection to alcohol and other psychoactive substance abuse and addiction. Methods: A structured literature review was conducted, and an electronic search of the PubMed database was performed. The review process initially identified 653 articles, of which 11 were included in the review. Results: Smokers and alcohol users are more likely to report an adverse childhood experience compared to people who do not report harmful habits. Parental divorce was one of the most common negative experiences that affected 17-59.5% of the respondents. The results of the Adverse Childhood Experiences Survey are a potentially significant predictor of risky behaviour.
Predicting the Work-Life Balance of Employees Based on the Ensemble Learning Method
Authors: SUNAR Ayşe Saliha , TÜMEN Vedat
Published: June 2023

Work-life has a great impact on other parts of people’s lives. The effort made in the workspace would cause attrition, exhaustion, and health problems. Employers need to take necessary measures to keep employees motivated by helping them balance work and personal lives. Employers could use many different techniques to measure their workers’ work-life balance and analyze them such as questionnaires and machine learning techniques. This research has been carried out to cluster the employees based on the level of attrition using effort and work-life balance parameters. In order to accomplish this, machine learning including ensemble learning techniques is used. An ensemble learning algorithm, random forest, performed almost the same as the support vector machine with the highest score, 95%. Almost all algorithms whether or not they are a member of ensemble learning performed with the f-score of 86%. However, one of the ensemble learning models, xGBoost, performed poorly with the lowest f-score of 69%. All algorithms predicted the lowest and the highest work-life balance scores, however, confused predicting the middle scores (class 2 and class 3).
Sentiment Analyzing from Tweet Data’s Using Bag of Words and Word2Vec
Authors: AYDIN Yıldız
Published: June 2023

Twitter sentiment classification is an artificial approach for examining textual information and figuring out what people's publicly tweets from a variety of industries are experiencing or thinking. For instance, a large number of tweets containing hashtags are posted online every minute from one user to some other user in the commercial and politics fields. It can be challenging for scientists to correctly comprehend the context in which specific tweet terms are used, necessitating a challenge in determining what is actually a positive or negative comment from the vast database of twitter data. The system's authenticity is violated by this issue and user dependability may be significantly diminished. In this study, twitter data sent to interpret movies were classified using various classifier and feature methods. In this context, the IMDB database consisting of 50000 movie reviews was used. For the purpose of anticipating the sentimental tweets for categorization, a huge proportion of twitter data is analyzed. In the proposed method, bag of words and word2vec methods are given by combining them instead of giving them separately to the classifier. With both the suggested technique, the system's effectiveness is increased and the data that are empirically obtained from the real world situation may be distinguished well. With experimental efficiency of 90%, the suggested approach algorithms' output attempts to assess the reviews tweets as well as be able to recognize movie reviews.
Recycling Wastewater with Membrane Technology and The Case of Singapore
Authors: YENİÇERİ Mikail , TORTUM YENİÇERİ Kübra
Published: June 2023

In this review study, as an alternative to rapidly depleting water resources as a result of increased use of water over the world, it has been discussed how wastewater can be treated and reused by membrane technology and reuse of wastewater as drinking water by using NEWater application in Singapore.
Lichens as Biomonitors of Air Pollutants Deposition: Strategically Important Element Pollution
Authors: ARSLAN TOPAL Emine Işıl , TOPAL Murat , ÖBEK Erdal , ASLAN Ali
Published: June 2023

Investigation of various species of lichen as biomonitors of air pollutants deposition and evaluation of element pollution were aimed. Maximum accumulation was 43.9±2.1 mg/kg in X. somloensis. Strontium in lichen species was quite high. Percentages of strontium for L.pulmonaria, C.furcata, U.longissima, X.somloensis, and F.caperata were between 58% and 78% indicating the efficient accumulation of strontium. Lichens were also accumulated strategically important elements. Maximum contamination factors in lichens were for strontium and tantalum. Maximum contamination factors of hafnium, niobium, lithium, gallium, and bismuth were for L. pulmonaria while maximum contamination factors of strontium, yttrium, scandium, and cerium were for X.somloensis. Maximum contamination factor of tantalum was for F.caperata. Enrichment factors for L.pulmonaria, C.furcata, and F.caperata were higher than 10, only for bismuth while lower than 10 for U.longissima. Enrichment factors for X.somloensis were higher than 10. Pollution load indexes for L.pulmonaria and U.longissima were higher than 1. Presence of strategically important elements in lichens showed that lichen species can be used as biomonitors of air pollutants.
Estimating The Location of a Buried Body from Magnetic Anomaly Through Normalized Full Gradient: A Case Study from The Sapinuwa Ancient City, Turkey
Authors: ÖZYALIN Şenol , AKÇIĞ Zafer
Published: June 2023

In geophysics, whether the structure is close to the surface or deeper, information about the depth and location of the structure can be obtained by using magnetic data. The importance of this study is an example of the application of the Normalized Full Gradient (NFG) method to an archaeological site to find the depth and location of structures that cause magnetic anomalies collected at the archaeological site. One of the parameters affecting the shape and size of the magnetic anomaly is the depth of the source causing the anomaly. For this reason, it is significant to determine the location of the source correctly. One of the methods used to determine the depth of structure using magnetic field data is NFG technique. In the application of downward analytical continuation, distortions due to the passage of mass depth occur and this method invalidates this. The NFG technique was tested on anomalies caused by prism-shaped synthetic models. Test studies on synthetic models with the NFG technique have yielded satisfactory findings. Based on the findings, the NFG technique was carried out to the real magnetic anomaly collected in the ancient city of Sapinuwa. The findings were compared with the building remains unearthed as a result of the proposed trench excavations. The obtained results have shown satisfactory results.
Adaptación del cuestionario de valoración de competencias digitales en educación superior
Authors: Revuelta-Domínguez Francisco-Ignacio , Suárez-Guerrero Cristobal , Rivero-Panaqué Carol , Cartagena-Beteta Mario-Armando
Published: June 2023

En este trabajo se presenta un estudio realizado en Perú con la población de estudiantes Beca 18 del Ministerio de Educación, ayuda social que inyecta el gobierno peruano a los estudiantes de Alto rendimiento del Perú. Pretende ofrecer un enfoque psicométrico del instrumento Cuestionario de Competencias Digitales en Educación Superior (CDES) en dicha población, así como su adaptación transcultural. La muestra final es amplia (N=10842) lo que permite desgranar y conocer la relevancia asociada entre la valoración que ofrece esta muestra específica de estudiantes superiores sobre las competencias digitales cuando se presenta una falta de recursos económicos previa. Las condiciones ofrecen varias lecturas interpretativas. Finalmente, se observa que el instrumento es adecuado y pertinente para muestras específicas corroborándose los datos de validación y translación cultural. Además, se observan valores muy elevados de relevancia e importancia de las competencias digitales significativa y derivada de condiciones sociales desfavorecidas.
Chemerin as a cardiovascular biological marker: Present and future
Authors: Alieva Amina M. , Reznik Elena V. , Teplova Natalia V. , Baykova Irina E. , Shnakhova Lidiya M. , Kotikova Irina A. , Shekshebekova Alpiyat M. , Nikitin Igor G.
Published: June 2023

Cardiovascular diseases are the leading cause of invalidity and mortality in the majority of developed countries and are recognized by the international community as a pandemic problem. An important task of modern cardiology is the search and study of new biological markers.
This literature review aimed to consider chemerin as a new diagnostic and prognostic marker for cardiovascular pathologies. Thus far, studies on chemerin indicate the possibility of its use as a marker of cardiovascular pathology. Evidence points to the important role of chemerin in the development and progression of cardiovascular diseases. As an adipokine, chemerin modulates glucose, and lipid levels, thereby influencing lipid deposition in the endothelium and progression of atherosclerosis. As a chemoattractant, it facilitates the mobilization and interaction of macrophages with dendritic cells and natural killer cells in the vascular system and induces endothelial angiogenesis. The established role of chemerin in vascular inflammation, angiogenesis, and blood pressure modulation opens serious prospects for the development of therapeutics targeting this biomarker for the treatment of cardiovascular diseases. Several candidates targeting chemerin and the CMRK1 signaling pathway have shown promising potential in reducing vascular dysfunction in in vitro and in vivo studies. Further studies analyzing the efficacy and safety of new chemerin-targeting drugs are needed to assess their potential.
Use of fibrin glue in the treatment of decubital ulcers in patients after brain damage, as a stage of conservative treatment
Authors: Shaibak Alexander A. , Horobrykh Tatiana V. , Altukhov Evgeny L. , Osmanov Elkhan G. , Yakovlev Alexey A.
Published: June 2023

BACKGROUND: Patients with brain damage require specific treatment for decubitus ulcers. Given the seriousness of their condition and decompensation of concomitant pathology, surgical treatment is not always possible. Conservative therapy can take a long time, which is aggravated by the unsolvable problem of patient immobilization, microcirculatory tissue disorders, and inevitable chronicity of the purulentinflammatory process. Most authors and practitioners are inclined toward a combined approach in the treatment of decubitus ulcers.
AIM: To evaluate the results of using fibrin glue in the treatment of bedsores in patients with severe brain damage.
MATERIALS AND METHODS: The article presents the experience of using fibrin glue in the conservative treatment of bedsores. The study included patients in a chronic critical state because of severe brain damage, with a decubitus ulcers area of 80 cm2 (stage III according to the Agency For Health Care Policy and Research classification). In the main group, treatment included the use of fibrin glue in accordance with the Russian Federation Patent No. 2777483 dated 08/04/2022. In the control group, treatment included standard dressings with levomekol ointment. Both groups received treatment for 21 days. Changes in the wound process were assessed using the BatesJensen scale and cytological examination at control points.
RESULTS: The study analyzed 58 patients, who were divided into two groups: group 1 (main) included 32 patients (15 men, 17 women), and group 2 (control) included 26 patients (12 women, 14 men). In the main group, after 1 week of applying dressings with fibrin glue, positive changes were noted, such as active marginal epithelialization, disappearance of undermining and swelling of wound edges, appearance of juicy bright granulations, and absence of exudates. After 22.5 weeks, epithelialization exceeded 50% of the total area of the decubitus ulcers (56.2% of cases), and exudation was completely absent. In a cytological study, the percentage of cells responsible for tissue proliferation increased and inflammation decreased in the main group. No significant effect was noted in the control group. In 7.7% of cases, 50% epithelialization was noted on days 2835; in three patients, re-infection of the decubitus ulcers occurred, and ischemia developed, which significantly lengthened the total duration of inpatient treatment and rehabilitation by 1.01.5 months.
CONCLUSION: The use of fibrin glue promotes decubitus ulcers epithelization, thereby reducing their size, up to complete healing.
To the сentenary of the department of maxillofacial surgery and dentistry of the Pirogov Russian National Research Medical University
Authors: Khelminskaya Natalya M. , Posadskaya Aleksandra V. , Kravets Viktor I. , Eremin Dmitriy A. , Pakhomova Elisaveta S.
Published: June 2023

The article is devoted to the transformation of the scientific directions of the Department of Maxillofacial Surgery and Dentistry of the Pirogov Russian National Research Medical University over a 100-year period of development, the history of the creation of the first department of this profile in Russia, modern work on clinical bases.
Modern aspects of diagnosis and treatment of subjective manifestations and accommodation disorders in patients — professional users of personal computers (systematic review)
Authors: Belikova Elena I. , Gatilov Denis V. , Ovechkin Nikolai I. , Eskina Erika N.
Published: June 2023

A systematic review was performed in the RSCI and PubMed databases using the following keywords: Computer vision syndrome, Digital eye strain, Accommodation, Accommodative asthenopia, RTS, and Quality of life. Eligible articles were evaluated in accordance with the criteria for prospective or retrospective studies. A total of 792 sources were analyzed, further using systematic review filters and authors knowledge of the topic. The retrospective analysis spanned 7 years (20162022).
Data indicated that accommodative asthenopia (AA), as a functional visual disorder, is a natural state of the accommodative system of the eye caused by long-term exposure to visually intense work on a personal computer. AA is characterized by a wide range of subjective manifestations (complaints) and indicators of the examination of the patients vision, associated primarily with objective accommodation. A differentiated approach to the diagnosis of various forms of AA, such as habitual excessive stress of accommodation and asthenic form of accommodative asthenopia, is important to provide adequate treatment based on methods with direct physical effects on the eye (such as low-energy laser radiation, magnetophoresis, and stimulation of accommodation), opto-reflex treatment, and an outpatient course as part of home training.
Penerapan manajemen asi eksklusif dan MP-ASI kepada masyarakat Kelurahan Temas Kota Batu
Authors: Katmawanti Septa , Paramita Farah , Kurniawan Agung , Samah Dea Aflah , Adisa Meyralda Dara , Hafizhah Nabila Alifatus , Zahro Nimas Dewi Aninatus , Pahlevi Reza
Published: June 2023

Desa Temas adalah salah satu desa di Kecamatan Batu Kota Batu yang memiliki jumlah penduduk pada tahun 2020 sebanyak 18.081 jiwa Ada beberapa masalah kesehatan yang terjadi di masyarakat Desa Temas. Salah satunya adalah rendahnya cakupan ASI eksklusif dan MP-ASI di wilayah Dinas kesehatan Batu cenderung rendah. Oleh karena itu, diperlukan upaya penerapan manajemen ASI eksklusif dan MP-ASI. Masyarakat masih belum memprioritaskan buruknya status gizi anak sebagai masalah kesehatan masyarakat dan tidak hanya pilihan gaya hidup. Oleh karena itu, dibutuhkan program untuk meningkatkan manajemen pemberian ASI eksklusif dan MPASI dengan cara sosialisasi dan praktik. Metode dalam pengabdian ini meliputi beberapa tahapan, yakni: 1) Koordinasi dengan mitra terkait; 2) Persiapan tempat dan fasilitas untuk Abdimas; 3) Sosialisasi mengenai Manajemen ASI eksklusif dan MP-ASI; 4) Lomba kreasi menu MP-ASI. Kegiatan ini dapat meningkatkan pengetahuan ibu mengenai manajemen ASI eksklusif dan MPASI, sehingga secara tidak langsung akan berkontribusi dalam peningkatan status gizi balita.
Upaya penurunan masalah gizi pada anak melalui kegiatan orientasi motivator ASI di Dinas Kesehatan Kabupaten Jombang
Authors: Nuriyah Sayyidatina Alfu , Ningtyias Farida Wahyu , Wahyuningsih Sri
Published: June 2023

Permasalahan gizi pada anak yang saat ini masih menjadi prioritas di Wilayah Kerja Dinas Kesehatan Kabupaten Jombang adalah gizi buruk. Gizi buruk adalah suatu keadaan yang terjadi karena rendahnya konsumsi makanan dengan kandungan energi dan protein dan atau diakibatkan karena adanya gangguan penyakit tertentu. Gizi buruk dapat menyebabkan terjadinya masalah pada metabolisme karbohidrat, protein, hormon, lemak, reseptor, dan gen yang mengakibatkan terjadinya penyakit kardiovaskular dan degeneratif di masa mendatang. Kegiatan Orientasi Motivator ASI dilakukan sebagai upaya untuk menurunkan kejadian gizi buruk di Kabupaten Jombang. Kegiatan Orientasi Motivator ASI yang dilaksanakan di Seksi Kesehatan Keluarga dan Gizi Masyarakat, Bidang Kesehatan Masyarakat Dinas Kesehatan Kabupaten Jombang. Peserta Orientasi Motivator ASI adalah bidan desa sebanyak 75 orang yang dibagi dalam 3 angkatan, satu angkatan terdiri dari 25 orang dari 34 Puskesmas. Kegiatan dilakukan dengan 3 tahapan yaitu perencanaan, pelaksanaan, dan pengawasan. Evaluasi kegiatan dilakukan melalui Quiz, Pre Test, dan Post Test. Hasil yang diperoleh yaitu peserta yang sudah dilatih dalam Kegiatan Orientasi Motivator ASI mampu menjadi Pembina Kelompok Pendamping ASI (KP-ASI) yang baik dan melanjutkan program tersebut di wilayah dan instansi masing-masing, sehingga ada keberlanjutan program dan menghasilkan perubahan perilaku pada ibu balita dalam pemberian ASI Eksklusif yang akan berdampak pada penurunan gizi buruk di Kabupaten Jombang.
Penerapan dynamic stretching dan latihan fisik anak usia 10-13 tahun melalui training of trainer pelatih sekolah sepak bola
Authors: Amiq Fahrial , Hariyoko Hariyoko , Hariyanto Eko
Published: June 2023

Di dalam olahraga sepak bola, pemanasan harus melibatkan aktifitas-aktifitas yang dapat meningkatkan suhu tubuh serta otot, yang berguna untuk mempersiapkan tubuh untuk game atau sesi latihan selanjutnya. Salah satu model pemanasan yang sering dilakukan oleh pemain atau tim sepak bola profesional adalah pemanasan dinamis. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk memberikan pengetahuan dan pemahaman kepada para pelatih sekolah sepak bola di Kota Malang tentang model-model pemanasan dinamis serta model latihan fisik untuk anak usia 10-13 tahun. Metode yang dilaksanakan dalam kegiatan pengabdian kepada masyarakat ini adalah dengan menggunakan metode teori dan praktek. Bentuk kegiatan pengabdian masyarakat ini dilaksanakan dengan cara menyelenggarakan workshop kepada pelatih Sekolah Sepak Bola Kota Malang yang berjumlah 30 orang tentang penerapan pemanasan dinamis dan latihan fisik untuk anak usia 10-13 tahun. Materi-materi yang disampaikan oleh narasumber dalam kegiatan pengabdian ini meliputi; definisi stretching dan pemanasan, pendapat yang menentang stretching statis sebelum sesi latihan atau pertandingan, pola pemanasan yang ideal, definisi latihan fisik, biomotorik dasar, karakteristik anak usia 10-13 tahun, model-model latihan fisik anak usia grassroot (10-13 tahun). Hasil dari kegiatan workshop ini adalah pelatih Sekolah Sepak bola Kota Malang memahami fungsi dari pemanasan dinamis dan bentuk-bentuk pemanasan dinamis dalam permainan sepak bola, serta memahami model latihan fisik untuk anak usia 10-13 tahun.
Table of Contents
Authors: The Ohio Academy of Science
Published: June 2023

No abstract available.
Back Matter
Authors: The Ohio Academy of Science
Published: June 2023

No abstract available.
“Essa Cidade Também é Minha”: o graffiti como manifestação da psique de sujeitos urbanos excluídos
Authors: Echegaray Luciana
Published: June 2023

Resumo: O artigo tem por objetivo demonstrar que o modo como a cidade é planejada influencia na formação de subjetividade humana. Este trabalho tematiza, por meio dos métodos de revisão bibliográfica, depoimentos e registro fotográfico, questões relacionadas à ocorrência do graffiti no espaço urbano como forma de insurgência e de protesto ao modelo de urbanismo hegemônico e excludente, vigente principalmente nas grandes cidades. Neste cenário emergem os grafiteiros, grupo que procura redefinir a paisagem urbana através de intervenções estéticas, funcionais e visuais, em sua busca por pertencer ao lugar, ao mesmo tempo em que denunciam sua exclusão desse espaço. A narrativa foi construída através de abordagem hipotético-dedutiva, com caráter exploratório, descritivo, explicativo e qualitativo. Como decorrência, conclui-se que o graffiti acaba também por revelar a psique e as subjetividades dos sujeitos produtores desta expressão simbólica e material.

(Pesquisa aprovada pelo CEP/UFRGS/ Comitê de Ética em Pesquisa da UFRGS, inscrita no CAAE sob número 16292919.6.0000.5347, parecer final de aprovação número 3.480.294).

Palavras-chave: Graffiti; Insurgência; Exclusão Socioespacial; Invisibilidade; Psique.
THE USE OF STATISTICAL METHODS IN PEDAGOGICAL RESEARCH IN HIGHER EDUCATION
Authors: Hrebnieva Iryna , Pakhnenko Iryna , Melnyk Alla , Lysenko Yanina , Tielietova Svitlana
Published: June 2023

In the article, based on the analysis of the state of the theory and practice of using statistical methods by teachers in pedagogical research, a research hypothesis is formulated: information and pedagogical support for the use of statistical methods in pedagogical research. The organizational-pedagogical and ethical-pedagogical conditions for designing information and pedagogical support for the use of statistical methods in pedagogical research are determined. The structure of information and pedagogical support for the use of statistical methods in pedagogical research has been developed. The stages are identified and the content of the system of information and pedagogical support for the use of statistical methods in pedagogical research by means of theoretical modeling is determined. The criteria of teachers' readiness to use statistical methods in pedagogical researches are revealed. The effectiveness of the system of information and pedagogical support for the use of statistical methods in pedagogical research has been proved.
TRAUMA THEORY IN MARY WOLLSTONECRAFT’S MARIA
Authors: Adhikari Anasuya , Rezaul Karim Mohammed , Saha Birbal , Sen Subir
Published: June 2023

Maria: or, The Wrongs of Woman, asserts and protests strenuously against the rigid laws that enslave women. The piece of work sheds light on the prevailing morality, which believes that chastity, repentance and submission should be the only virtues of women. Mary Wollstonecraft’s posthumous work is equipped with such powerful political statements. Maria’s character is nothing but a written defence against her oppressive and abusive husband’s misconducts against her. Wollstonecraft pens this feminist manifesto to denounce the numerous wrongs that are done to women. Her proclamation stands tall, demanding women’s right to be free of male oppression. In this research work, we would like to draw not only on the measurements of Maria: or, The Wrongs of Woman but also take a different path, focusing on a theme that is central to the novel and its feminist politics which has received little attention so far: trauma. The novel is a structuring of intertwined life events of suffering and ruptured relationships. We would here delve deep into the novel; the protagonist’s life events and the writer’s concerns through Trauma Theory.
PROVIDING INCLUSIVE LEARNING AT HIGHER SCHOOL
Authors: Nahorna Olena , Lytovchenko Svitlana , Tripak Marian , Serhiienko Tamara , Khmil Iryna
Published: June 2023

Providing inclusive learning at higher school is fulfilled on the basis of using specialized infrastructure, pedagogical practice and pedagogical workers’ effective work. An important direction of the study in the academic paper is the analysis of the key principles of forming inclusive learning at higher school using the experience of developed countries and its implementation in pedagogical practice. The issue of ensuring inclusive education is an urgent one for the social policy of any country, as it plays a significant role in ensuring the development of human capital and promoting demographic policy. The purpose of the present academic paper is to analyze the features of organizing inclusive learning at higher school. The state policy for inclusive education formation should include several measures aimed at improving the educational environment, training highly qualified pedagogical workers and a number of tools used during the educational process. The academic paper studies the key principles of organizing inclusive learning and the basis for its further development. Particular attention is paid to the issue of using the means of organizing inclusive education aimed at developing emotional and academic intelligence. The scientific article outlines the basic principles of establishing inclusive education and opportunities for improving the implementation quality. The research results indicate the necessity to improve the state social policy, the introduction of innovative infrastructure and specialized means used to improve the quality of inclusive education. The obtained results can be used for modern higher schools in order to ensure an effective educational process.
National Evaluation of the Professional Nurse Advocate Programme in England: SUSTAIN – Supervision, Support, Advocacy for Improvement in Nursing, Mixed Methods study.
Authors:   Coventry University, UK, Lees-Deutsch Liz , Kneafsey Rosie ,   Coventry University, UK, Rodrigues Amorim Adegboye Amanda ,   Coventry University, UK, Bayes Natasha ,   University of Northampton, UK, Palmer Shea ,   Cardiff University, UK, Chauntry Aiden ,   The University of North Carolina at Chapel Hill, North Carolina, USA, Khan Mariam ,   Coventry University, UK
Published: June 2023

The Professional Nurse Advocate (PNA) programme is a clinical and professional leadership programme delivered by Higher Education Institutions (HEI) which equips nurses with the skills to deliver restorative clinical supervision to colleagues in England. The programme has been gradually rolled out across England during 2021/22 with the aim of ensuring there will be PNAs in place to support colleagues in the following specialties: Critical care, Mental Health (Adult Acute & Children and Young Peoples inpatient settings) Community, Learning Disabilities (Adult), Children and Young People, Safeguarding, Health & Criminal Justice settings (HCJ), and International Nurses. In February 2022, NHSE sought an evaluation of the PNA programme. A research team from Coventry University was commissioned to undertake this work. This Executive Summary Report sets out the methods, activities, findings, and recommendations as requested by commissioners.
Amino Acid Profile of Luminal A and B Subtypes Breast Cancer
Authors: Panigoro Sonar Soni , Kurniawan Arif , Ramadhan Ramadhan , Sukartini Ninik , Herqutanto Herqutanto , Paramita Rafika Indah , Sandra Ferry
Published: June 2023

BACKGROUND: Amino acids are important for proliferation and maintenance of tumor cells. Breast cancer patients were found to have significant changes in the number of amino acids, which are assumed to be correlated with the molecular subtypes of breast cancer. Therefore, current study was conducted to analyze plasma amino acids in breast cancer patients with luminal A and B subtypes.METHODS: Breast cancer and control subjects were recruited, and venous blood was collected for the measurement of plasma amino acids. Total 19 plasma amino acids were measured using reverse-phase high-performance liquid chromatography with C18 column. Mean comparison for normally distributed and homogeneous data was further analzyed using independent sample T-test, with p<0.05 was considered as significant.RESULTS: From total 19 amino acids, only 7 amino acids; cysteine, glutamic acid, histidine, ornithine, threonine, tyrosine, valine, were statistically different between the healthy control and breast cancer subjects. Eventhough no amino acids was found to be statistically different between breast cancer subjects with luminal A and B subtypes, but some amino acids were found to be significantly different when correlated to various breast cancer risk factors.CONCLUSION: Amino acid profile of patients with Luminal A and B subtypes of breast cancer differs compared to healthy controls and is also correlated with breast cancer risk factors. Increase in cysteine level in Luminal A subtype patients and decrease of alanine and leucine in Luminal B subtype patients can be used as a biomarker.KEYWORDS: amino acid, plasma, breast cancer, risk factor, biomarker