bluuebunny/crossref_metadata_2025 huggingface dataset:
An Artistic Image Fusion Method with Improved Cartoon-Texture Decomposition
Authors: Meng Zhou
Published: May 2022

When the art images are restored by the virtual restoration method, there are problems such as insufficient clarity and more noise in the reference image. An improved cartoon-texture decomposition method for art image fusion is proposed. The nonlinear local total variation component is used as the indicator function of image decomposition to obtain the image cartoon structure component and texture oscillation component. According to the oscillation component’s strong repetitiveness and structural directionality, the image texture part is filtered by combining the improved directional diffusion algorithm. Using the sparse coefficients of the fused cartoon component and the sparse coefficients of the texture component, the cartoon and texture of the image is inverse transformed and weighted and summed to obtain the recovered image after fusion. The experimental results show that this paper has a good effect after image fusion, and the recovered clarity is higher, which can better express the basic information of the source image; compared with several decomposition fusion methods commonly used at present, this paper has better recovery performance and detail processing ability and preserves the edge information of essential details in the image while filtering and denoising and is more excellent in objective performance evaluation indexes such as PSNR and SSIM. It can be used as a reference basis in the restoration process of art images.
A Systematic Review on Hybrid Intrusion Detection System
Authors: Maseno Elijah M. , Wang Zenghui , Xing Hongyan
Published: May 2022

As computer networks keep growing at a high rate, achieving confidentiality, integrity, and availability of the information system is essential. Intrusion detection systems (IDSs) have been widely used to monitor and secure networks. The two major limitations facing existing intrusion detection systems are high rates of false-positive alerts and low detection rates on zero-day attacks. To overcome these problems, we need intrusion detection techniques that can learn and effectively detect intrusions. Hybrid methods based on machine learning techniques have been proposed by different researchers. These methods take advantage of the single detection methods and leverage their weakness. Therefore, this paper reviews 111 related studies in the period between 2012 and 2022 focusing on hybrid detection systems. The review points out the existing gaps in the development of hybrid intrusion detection systems and the need for further research in this area.
Emotion Analysis Method of Teaching Evaluation Texts Based on Deep Learning in Big Data Environment
Authors: Li Liqin
Published: May 2022

Accurate emotion analysis of teaching evaluation texts can help teachers effectively improve the quality of education and teaching. In order to improve the precision and accuracy of emotion analysis, this paper proposes an emotion recognition and analysis method based on deep learning model. First, LTP tool is used to effectively process the teaching evaluation texts data set to improve the completeness and reliability of the data. Based on bidirectional long short-term memory (BiLSTM) network, an emotion analysis model is constructed to enhance the long-term memory ability of the model, so as to learn the emotion feature information more fully. On the basis of this model, the attention interaction mechanism module is introduced to pay attention to the important information in the attribute sequence, mine the deeper emotion feature information, and further ensure the accuracy of emotion recognition of teaching evaluation texts. Experimental simulation results show that the accuracy and precision of emotion recognition of the proposed method are 0.9123 and 0.8214, which can meet the needs of accurate emotion analysis of complex teaching evaluation texts.
Cochlear Implantation in a Patient with Neurofibromatosis Type 2 and an Intracochlear Schwannoma: A Case Report and Literature Review
Authors: Zhang Dejun , Fu Zeming , Han Shuang , Guo Fang , Tang Na , Zhao Ying , Guan Guofang
Published: May 2022

A primary intracochlear schwannoma (ICS) is a unique type of vestibular schwannoma (VS); the tumor originates from the terminal branches of the cochlear nerve and is confined to the cochlea. An ICS is the most common subtype of schwannoma in the inner ear. As an ICS is clinically rare, diagnosis and treatment remain challenging. We report a rare case of cochlear implantation (CI) in a patient with neurofibromatosis type 2 and an ICS. The patient exhibited bilateral, profound, sensorineural hearing loss. The tumor on one side was a common VS treated via tumor and acoustic nerve resection and that on the other side an ICS. To ensure auditory rehabilitation via CI, we performed CI while removing part of the ICS via an enlarged round window. Auditory rehabilitation was satisfactory. Thus, ICS patients, especially those who urgently require auditory rehabilitation, can undergo simultaneous CI and (total or partial) tumor removal. However, the long-term results require close observation.
Stiff Person Syndrome: A Case Report with Sudden Onset and Coexistence of Sero-Positive Antibodies to Glutamic Acid Decarboxylase and Anti-SOX1 Antibodies
Authors: Nguyen Phuong Minh , Vu Dung Duy , Vu Kien Dung , Nguyen Hai Thanh , Nguyen Dinh Van
Published: May 2022

Stiff Person Syndrome (SPS) is an extremely rare neurological condition characterized by muscle stiffness and painful muscle spasms. The symptoms often progress slowly and can cause disability. Antibodies to glutamic acid decarboxylase (anti-GAD) have been reported in up to 80% of the classic type of SPS. Paraneoplastic syndrome comprises 5% of SPS cases. These patients present with different malignancies including lung, thymus, breast, colon, and lymph nodes. In this paper, we report a case of a 25-year-old Vietnamese female patient with SPS presenting with unusual clinical manifestations of sudden onset, rapidly progressive spinal, abdominal, and lower limb rigidity accompanied by painful spasms, autonomic disorders, and severe, multiple bone fractures. Serologic tests detected high-titer anti-GAD, combined with anti-SOX1 antibodies, suggesting paraneoplastic SPS. Intravenous immunoglobulin has been employed as the main treatment therapy, and the patient has had a complete remission.
Transactional Relations between Child Functioning and Parenting Stress in the First Years of Life: A Longitudinal Study among Psychosocially Burdened Families
Authors: Evers Oliver , Georg Anna Katharina , Wegener Charlotte , Sidor Anna , Taubner Svenja
Published: May 2022

Introduction: Previous research reported transactional relations between child functioning and parenting stress. There is limited evidence whether a transactional developmental model also fits children below the age of 12 months, especially in psychosocially burdened families. This study aims to test the fit of a transactional model during the first 3 years of life and examines whether the model differs between families with low and high psychosocial burden. Methods: A total of 302 psychosocially burdened families were observed over 3 years at age 4, 12, 24, and 36 months. Child behavioral problems and parenting stress were assessed via self-report while psychosocial burden was assessed via external rating at baseline. Cross-lagged panel analysis was used to investigate the fit of a transactional model. Results: A transactional model fitted the data significantly better (Δχ2 = 81.87, p < 0.001) than an autoregressive model reaching acceptable to good fit indices (CFI = 0.96, RMSEA = 0.09). The model indicated moderate stability within and reciprocal effects between child behavioral problems and parenting stress from age 12 to 36 months. From age 4 to 12 months, parenting stress predicted child behavioral problems but not vice-versa. Model fit indices and transactional relations did not substantially differ between families with low and high psychosocial burden, except for child effects on parenting stress during the first year of life, which were only evident in higher burdened families. Conclusion: Transactional relations among child and parent variables are evident in the first 3 years of life. Child effects in the first year of life may be restricted to highly psychosocially burdened families. Future research may focus on potential mediating variables such as parental sensitivity or contextual variables like significant life events. Targeted prevention strategies should be adapted to the level of psychosocial burden to account for the differing transactional relations.
Looking at Interleukin-22 from a New Dermatological Perspective: From Epidermal Homeostasis to Its Role in Chronic Skin Diseases
Authors: Prignano Francesca , Donetti Elena
Published: May 2022

Twenty years after the cloning, characterization, and identification of interleukin (IL)-22 in 2000, the precise biological role of this cytokine in healthy and unhealthy skin is not completely known. The aim of this review is to provide an overview on the recent knowledge available in literature about the origin, sources, targets, molecular mechanism of action, and clinical issues regarding IL-22. Last but not least, recent experimental evidence obtained in a 3D model of organotypic culture of normal human skin highlights its homeostatic role and will be discussed in detail, as personal observations. As most of the data concerning IL-22 immunomodulating activity are obtained from mouse models, this work offers a new perspective on its clinical role. The hypothesis herein advanced is that IL-22 profoundly affects keratinocyte terminal differentiation, whereas, in order to induce a proliferation impairment, a more complex psoriatic-like microenvironment is needed.
Side-Viewing Duodenoscope versus Forward-Viewing Gastroscope for Endoscopic Retrograde Cholangiopancreatography in Billroth II Gastrectomy Patients
Authors: Marques de Sá Inês , Chaves Carlos Borges , Correia de Sousa João , Fernandes João , Araújo Tarcísio , Canena Jorge , Lopes Luís
Published: May 2022

Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with Billroth II gastrectomy is still a challenging procedure. The optimal approach, namely the type of endoscope and sphincter management, has yet to be defined. Aim: To compare the efficacy and safety of forward-viewing gastroscope and the side-viewing duodenoscope in ERCP of patients with Billroth II gastrectomy. Methods: We conducted a retrospective, single-center cohort study of consecutive patients with Billroth II gastrectomy submitted to ERCP in an expert center for ERCP between 2005 and 2021. The outcomes assessed were: papilla identification, deep biliary cannulation, and adverse events (AEs). Multivariate analysis was performed to evaluate potential associations and predictors of the main outcomes. Results: We included 83 patients with a median age of 73 (IQR 65–81) years. ERCP was performed using side-viewing duodenoscope in 52 and forward-viewing gastroscope in 31 patients. Patients’ characteristics were similar in the two groups. The global rate of papilla identification was 66% (n = 55). The rate of deep cannulation was 58% considering all patients and 87% in the subgroup of patients in which the papilla major was identified. Cannulation was performed with standard methods in 65% of cases and with needle-knife fistulotomy in 35%. AEs occurred in 4 patients. There was no difference between duodenoscope and gastroscope in papilla identification (64% [95% CI: 51–77] vs. 71% [55–87]). Although not statistically significant, duodenoscope had a lower deep cannulation rate when considering all patients (52% [15–39] vs. 68% [7–35]) and a higher AEs rate (8% [1–15] vs. 0% [0–1]). In a multivariate analysis, the use of gastroscope significantly increased the deep cannulation rate (OR = 152.62 [2.5–9,283.6]). Conclusion: This study demonstrates that forward-viewing gastroscope is at least as effective and safe as side-viewing duodenoscope for ERCP in patients with Billroth II gastrectomy. Moreover, our study showed that gastroscope is an independent predictor of successful cannulation.
Bilateral Vocal Cord Paralysis Associated with Meningeal Carcinomatosis from Lung Adenocarcinoma
Authors: Yamada Gohei , Toyoda Takanari , Katada Eiichi , Matsukawa Noriyuki
Published: May 2022

Cranial neuropathy is a clinical manifestation of meningeal carcinomatosis (MC); however, the glossopharyngeal and vagus nerves are rarely impaired. Therefore, dysphagia and bilateral vocal cord paralysis (BVCP) are extremely rare manifestations of MC. Here, we present a case of MC from a lung adenocarcinoma presenting with dysphagia and BVCP. An 84-year-old man with a 4-year history of left lung adenocarcinoma developed dysphagia and hoarseness. Flexible nasopharyngoscopy revealed BVCP. Ten days later, the patient developed stridor and respiratory distress. A tracheotomy was performed to prevent airway obstruction. Gadolinium-enhanced magnetic resonance imaging (MRI) of the brain showed enhancement of the bilateral glossopharyngeal and vagus nerves, and several enhancing lesions in the right internal auditory canal, left cerebellum, fourth ventricle, pons, cerebral aqueduct, and right frontal lobe, suggesting MC and brain metastasis. Based on the clinical history of malignancy and the MRI findings, the patient was diagnosed with MC. As the patient refused additional treatment, including chemotherapy and radiation, only palliative care was provided. To the best of our knowledge, this was the first case of MC from a solid tumor presenting with BVCP. When patients with malignancy present with BVCP, MC should be considered.
Angiolipoma of the Colon: A Rare Cause of Gastrointestinal Bleeding
Authors: Patel Maya , Kim Eugene , Zhou Wendi , Ratuapli Shiva
Published: May 2022

Angiolipomas are benign, subcutaneous tumors that are rarely found in the gastrointestinal tract. Still, because they may present with abdominal pain and rectal bleeding, it is important to recognize the clinical, radiological, and endoscopic findings associated with these masses. Herein we report a case of an angiolipoma of the colon diagnosed in a 49-year-old male presenting with self-limited gastrointestinal bleeding who subsequently underwent surgical resection without complications.
Bruton’s Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae
Authors: Liu Zhe , De Porto Alexander P.N.A. , De Beer Regina , Roelofs Joris J.T.H. , De Boer Onno J. , Florquin Sandrine , Van’t Veer Cornelis , Hendriks Rudi W. , Van der Poll Tom , De Vos Alex F.
Published: May 2022

Humans with dysfunctional Bruton’s tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against infections is controversial. In this study, we determined the contribution of Btk in B cells and neutrophils to host defense against the extracellular bacterial pathogen Klebsiella pneumoniae, a common cause of pulmonary infections and sepsis. Btk−/− mice were highly susceptible to Klebsiella infection, which was not reversed by Btk re-expression in B cells and restoration of natural antibody levels. Neutrophil-specific Btk deficiency impaired host defense against Klebsiella to a similar extent as complete Btk deficiency. Neutrophil-specific Btk deficiency abolished extracellular reactive oxygen species production in response to Klebsiella. These data indicate that expression of Btk in neutrophils is crucial, while in B cells, it is dispensable for in vivo host defense against K. pneumoniae.
Tacrolimus Optic Neuropathy Mimicking Papilledema
Authors: Hussein Isra M. , Micieli Jonathan A.
Published: May 2022

Tacrolimus (FK506) is a potent and effective immunosuppressive agent, mainly utilized after solid organ transplantation. We report the clinical features of tacrolimus optic neuropathy (TON) in a patient on tacrolimus therapy that had an exhaustive workup not revealing any additional cause. The patient was a 60-year-old man post-cardiac transplantation who presented with a 5-month history of vision loss OD and 10 days of vision loss OS. Dilated exam showed significant optic disc edema in both eyes (OCT RNFL 442 μm OD and 330 μm OS). Multiple lumbar punctures showed a normal opening pressure. After discontinuation of tacrolimus, he noticed gradual improvement in his vision and 10-month follow-up revealed significantly improved visual function and resolved optic disc edema. This case report adds significant optic disc edema to the clinical characteristics of TON. TON should be suspected in any patient on this medication with a new optic neuropathy and negative workup for infectious or inflammatory causes. Discontinuation of the medication and change to cyclosporine can result in improvement in vision.
Pseudomembranous Conjunctivitis following Exposure to Arisaema ringens Sap: A Case Report
Authors: Ono Takashi , Nejima Ryohei , Kinoshita Katsuhito , Mori Yosai , Iwasaki Takuya , Miyata Kazunori
Published: May 2022

Plants of the Araceae family exude a sap containing calcium oxalate, a toxic substance that causes dermatitis. However, ocular injury due to exposure to Araceae sap has rarely been reported. Herein, we present a case of severe pseudomembranous conjunctivitis following exposure to Arisaema ringens, an Araceae species and popular houseplant in Japan. A 67-year-old man presented with pain in his right eye after exposure to the sap of A. ringens. At presentation, the best corrected visual acuity and intraocular pressure in the right eye were 20/800 and 15 mm Hg. Slit-lamp examination showed strong hyperemia, conjunctival chemosis, and corneal edema with many pseudomembranes, and fluorescein staining revealed corneal epithelial defects in the central area of the cornea. We washed the ocular surface with saline and initiated treatment with topical instillations of 1.5% levofloxacin and 0.1% betamethasone, combined with ofloxacin eye ointment. After repeatedly removing the pseudomembranes and increasing the frequency of the topical instillations, pseudomembranous conjunctivitis and corneal erosion gradually improved. One week following the injury, the corneal epithelial defects were no longer detectable, and the patient’s best corrected visual acuity recovered to 20/25. It is important for ophthalmologists and primary care physicians to be aware of the ocular toxicity of A. ringens and should counsel their patients accordingly. Moreover, preventative measures, such as the use of protective eyewear, should be taken when cutting this houseplant.
The Stem Cell Potential of O-2A Lineage Astroglia
Authors: Zhang Ye , Sun Yan-Yun , Xu Min , Shen Ling-Ling , Xia Chun-Lin
Published: May 2022

Astrocytes are the most common glial type in the central nervous system. They play pivotal roles in neurophysiological and neuropathological processes. Mounting evidence indicates that astrocytes may act as neural stem cells and contribute to adult neurogenesis. In previous reports, freshly isolated O-2A progenitors were shown to revert to neural stem-like cells (NSLCs) when cultured with a serum-containing glial medium or bone morphogenic proteins for 3 days and with basic fibroblast growth factor consecutively. NSLCs possess self-renewal and multipotential capacities that can give rise to neurons and glial cells, which suggests that they have stem cell-like properties. However, the underlying molecular mechanisms and cell fate commitment when exposed to a neural conditioned medium remain obscure. In this study, we demonstrated that NSLCs grown in the serum-containing neurobasal medium can differentiate into induced neural-like cells (iNLCs). It was noteworthy that astroglia mixed in these cells, particularly in iNLCs, were gradually replaced by neural phenotypes during this glia-neuron conversion. Remarkably, these glial cells can maintain high levels of proliferation and self-renewal ability by activating the NF-κB and MAPK signals. Finally, we found that Notch, STAT3, autophagy, bHLH, and Wnt signals appear to be critical modulators of these intricate events. Altogether, these data demonstrate that O-2A lineage astroglia can function as neural stem cells and display neurogenic plasticity. Dissecting the regulatory pathways involved in these processes is essential to the understanding of glial cell fate and its precise functions. This finding may foster a better understanding of astrocytic heterogeneity and lead to innovative ways to readily apply stem-like astroglia cells as candidate cell sources for neural repair.
Unstable Angina as a Component of Primary Composite Endpoints in Clinical Cardiovascular Trials: Pros and Cons
Authors: Kristensen Anna Meta Dyrvig , Pareek Manan , Kragholm Kristian Hay , Sehested Thomas Steen Gyldenstierne , Olsen Michael Hecht , Prescott Eva Bossano
Published: May 2022

Background: Unstable angina (UA) is a component of acute coronary syndrome that is only occasionally included in primary composite endpoints in clinical cardiovascular trials. The aim of this paper is to elucidate the potential benefits and disadvantages of including UA in such contexts. Summary: UA comprises <10% of patients with acute coronary syndromes in contemporary settings. Based on the pathophysiological similarities, it is ideal as a part of a composite endpoint along with myocardial infarction (MI). By adding UA as a component of a primary composite endpoint, the number of events and feasibility of the trial should increase, thus decreasing its size and cost. Furthermore, UA has both economic and quality of life implications on a societal and an individual level. However, there are important challenges associated with the use of UA as an endpoint. With the introduction of high-sensitivity troponins, the number of individuals diagnosed with UA has decreased to rather low levels, with a reciprocal increase in the number of MI. In addition, UA is particularly challenging to define given the subjective assessment of the index symptoms, rendering a high risk of bias. To minimize bias, strict criteria are warranted, and events should be adjudicated by a blinded endpoint adjudication committee. Key Messages: UA should only be chosen as a component of a primary composite endpoint in cardiovascular trials after thoroughly evaluating the pros and cons. If it is chosen to include UA, appropriate precautions should be taken to minimize possible bias.
Conceptual Understanding of Students Towards COVID-19 Pandemic: Basis for Inclusion in Science, Technology and Society (STS) Curriculum
Authors: Dantic Marshall James
Published: May 2022

The study has utilized a multi-methodology research design with assessment tests and a structured interview guide as instruments in gathering the data. In class 2020, there are 72 students and 8 Teachers of Science, Technology and Society (STS) who served as participants in the study. The assessment test was validated by three experts, Science, Technology and Society teachers with sciences as specialization and a professional education teacher. There are two types of instruments were used to gather data, these are (a) an assessment test and (b) structured interview guide. The assessment test is compose of two parts (I) the traditional multiple choice assessment test that is composed of 20 questions and (II) close-ended essay  which consists of five questions. The structured interview guide is composed of one question “In your perspective, should ‘COVID-19 Pandemic’ be included in a STS curriculum? Why?” The results of the study have concluded: level of understanding of the students based from the traditional and essay assessment tests are both fairly satisfactory; level of conceptual understanding based from the relationship between the assessment tests has moderate positive correlation; the perspectives of the teachers regarding the inclusion of COVID-19 Pandemic concept in the STS curriculum, seven themes have emerged. The themes focused on addressing COVID disparities experience across multiple dimension and use it for curriculum formulation and empowerment of STS literacy. The study has recommended; heighten and strengthen the students’ conceptual understanding toward COVID 19 Pandemic through series of topics and teaching approaches; strategically include the concept of COVID-19 pandemic in the curriculum.
Training and Development of Business Instructors in Relation to Faculty Performance
Authors: Pallega Lovelle P.
Published: May 2022

The study aims to describe the relationship between trainings and development of business educators and their performance in one of the state universities in Zamboanga Peninsula. Data mining technique was used in determining the profile of business educators, the number of seminars and trainings attended, and performance rating. Business instructors included the part-time, temporary and permanent faculty members. Results of the study revealed that faculty received more trainings related to instructions but very few in research, extension and production. Business educator’s performance were mostly very satisfactory across the four core functions despite the limited number of trainings received on some functions particularly to the new and young faculty. Further, there is a significant difference on the performance rating based on their employment status. However, study reveals that trainings and development have no significant relationship with performance. The study provides significant managerial implications on the evaluation of faculty performance and highlights the need to develop a framework for training and development. Moreover, the study recommends the need for the administration to revise its performance evaluation tool to obtain a more concrete and objective analysis in gauging how well the university performs in achieving its goals and targets.
Problems Encountered by School-Based Feeding Program Beneficiaries and Their Academic Performance
Authors: Vizcocho Daren Joy D.
Published: May 2022

Based Feeding Program beneficiaries and their academic performance in selected public school of Subic. This study was limited only to the three hundred forty (340) SBFP recipients of grade 4-6 elementary students in the District of Subic who were randomly selected. The study used descriptive survey method design.

The major findings include the following: There was significant difference between the academic performance of students before and after the implementation of the school-based feeding program. Social, Behavioral and Economic problems encountered had low negative relationship with academic performance of beneficiaries before and after the implementation. The null hypothesis was rejected; hence there is significant relationship between the problems encountered and the academic performance of SBFP.

The following recommendations are Employed parents may not take their child’s health nutritional status for granted by ensuring enough time to supervise their feeding habits of their child. School feeding coordinators may also look into the problems of the beneficiaries and not just providing them food during feeding time. School advisers and teachers may collaborate with parents/guardian of the SBFP beneficiaries in minimizing and eliminating the sources and cause of problems to attain higher level, if not the highest level of academic performance.
processamento da repetição no gênero textual entrevista televisiva
Authors: Melo Junior José Nildo Barbosa de , Morais Eduardo Pantaleão de
Published: May 2022

Este artigo pretende analisar a maleabilidade funcional da repetição como uma atividade de formulação textual da entrevista televisiva. O embasamento teórico fixa-se na Linguística Textual e na Análise da Conversação, por meio de Hoffnagel (2003), Fávero et al (2010), Koch (2010a, 2010b), Marcuschi (2015), Xavier (2006), Melo Junior (2017), além de outros autores. A metodologia é de linha qualitativo-interpretativa (FLICK, 2009), estabelecendo, processual e indutivamente, pontos de intersecção entre a teoria e as marcas textual-interativas no gênero. A amostragem constitui-se por uma entrevista gravada e transcrita do Programa do Jô, exibido na data 17/06/2016, iniciada aos 12m e 43s e finalizada aos 15m e 43s. O estudo aponta que a repetição não constitui um mero recurso tautológico, mas uma prática de construção do texto falado, a qual possibilita a manutenção da interação verbal entre entrevistador e entrevistado (sujeitos L1 e L2), a partir dos tipos vários de repetição.
Caracterização morfológica dos prenomes mais populares no Brasil nas décadas de 1930 a 2000: um estudo exploratório
Authors: Seide Marcia Sipavicius
Published: May 2022

Tanto nas gramáticas escolares quanto nos manuais de Morfologia pouca atenção é dada aos traços morfológicos dos nomes próprios pessoais. Diante dessa lacuna, este artigo apresenta um estudo exploratório baseado em dados do IBGE sobre os primeiros nomes mais populares do período de 1930 a 2000. Na amostra formada pela união das listas de nomes geradas pelo IBGE, há 13 sufixos na antroponímia masculina e 13 na antroponímia feminina, na qual também houve nome formado por composição aglutinante. A análise do valor de uso de cada sufixo mostrou que, enquanto o morfema feminino -a predomina na antroponímia feminina, há uso frequente dos morfemas zero, -el , -ão e -os na antroponímia masculina. Quanto à utilização dos sufixos no eixo cronológico, seu ciclo de uso é de três décadas na antroponímia masculina e dois na feminina. Em relação ao uso do par opositivo -o e -a em pares de prenomes populares em uma mesma década, os dados mostram que houve um ciclo de moda que durou duas décadas (1950 e 1960), não obstante seu uso ter sido constante ao longo de todo o período.
Notes on the Text of Diogo do Couto’s O Soldado Prático
Authors: Gorey Matthew M.
Published: May 2022

Despite its fame among critics and historians of Portuguese literature, the revised second version of Diogo do Couto’s O Soldado Prático has presented significant challenges to scholars seeking to establish a definitive edition of the dialogue. While the most recent edition, that of García Martín (2009), is a welcome improvement over earlier editions by Brasil (1988), Lapa (1937), and Amaral (1790), there remain a handful of passages in which the text can be further improved by a closer study of the Spanish books that Couto used as sources for the dialogue’s many classical anecdotes. This article proposes a number of corrections and emendations to García Martín’s edition by comparing the readings of the most reliable manuscript, BNP 463, with four 16th-century books that Couto consulted as sources of ancient sayings for his own dialogue.
Normal Values for Myocardial Work Indices Derived From Pressure-Strain Loop Analyses: From the CCHS
Authors: Olsen Flemming Javier , Skaarup Kristoffer Grundtvig , Lassen Mats Christian Højbjerg , Johansen Niklas Dyrby , Sengeløv Morten , Jensen Gorm Boje , Schnohr Peter , Marott Jacob Louis , Søgaard Peter , Gislason Gunnar , Svendsen Jesper Hastrup , Møgelvang Rasmus , Aalen John Moene , Remme Espen Wattenberg , Smiseth Otto Armin , Biering-Sørensen Tor
Published: May 2022

Background:

Pressure-strain loop analyses is a noninvasive technique capable of evaluating myocardial work. Reference values are needed to benchmark these myocardial work indices for clinical practice.

Methods:

Healthy participants from a general population study were used to establish reference values for global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE) measured by pressure-strain loop analyses. The relation to age and sex was examined. We furthermore examined the proportion of abnormal work indices according to low, intermediate, and high cardiovascular risk by the Framingham risk score.

Results:

The healthy sample consisted of 1827 participants (median age, 45 years; 39% men). Lower reference values were GWI, 1576 mm Hg%; GCW, 1708 mm Hg%; and GWE, 93.0% and upper reference value for GWW was 159 mm Hg%. Women exhibited significantly higher GWI, GCW, and GWW and lower GWE. Sex significantly modified the association between all indices and age (
P
for interaction: 0.001 for GWI, 0.009 for GCW, 0.003 for GWW, and 0.009 for GWE). For men, only GCW increased with age, whereas the other indices did not change with age. For women, GCW increased linearly with increasing age, whereas GWI, GWW, and GWE changed in a curvilinear fashion with age such that GWI increased in younger participants, GWW increased in elderly, and GWE declined concordantly. Abnormalities in myocardial work indices became more frequent with increasing Framingham risk score category (abnormal GWI: 2% versus 4% versus 5%,
P
=0.001; abnormal GCW: 2% versus 3% versus 4%,
P
=0.006; abnormal GWW: 3% versus 6% versus 11%,
P
<0.001; abnormal GWE: 3% versus 4% versus 11%,
P
<0.001).

Conclusions:

Myocardial work indices differ between sexes and change with age in a sex-dependent manner. Accordingly, we established age- and sex-specific reference values from a general population sample. Abnormal work indices become more frequent with higher clinical risk.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02993172.
School Gardens Education Plan through the Awareness of Elementary and Middle School Parents
Authors: Hong In-Kyoung , Yun Hyung-Kwon , Jung Young-Bin , Lee Sang-Mi , Lee Sang-Deok
Published: May 2022

Background and objective This study was conducted on the value and operation of school garden education. It will be presented as basic data in considering the necessity of a policy for revitalizing school gardens and financial support, and can be used to find ways to facilitate education through school gardens. Methods The collected data were analyzed using the χ2 test to obtain the frequency and weight of each measurement item, and the importance of each value was calculated by giving it a relative weight and directly evaluated so that the sum of importance was 100%. Results In terms of the effectiveness of each value indicator of school gardens, parents of children who had experienced school gardens perceived them as having educational value (4.35 points) and parents of children who had not experienced school gardens perceived them as having health value (4.38 points). The average amount parents were willingness to pay voluntarily as a fee for school garden programs was 5,889 won and the highest amount was 30,000 won, and the average amount of government budget support parents saw as appropriate was 6,705 won and the highest was 100,000 won. Regarding the appropriate rate of education tax increase from the current rate of 30% the maximum percentage acceptable was 0.531–0.545%. Both parents of elementary and middle school students answered that educational value is the most important of the specific values of school garden service. Regarding the necessity of expanding school garden education, 89.8% of parents answered that the trend of increasing school garden education is appropriate, 93.2% answered that they were willing to have their children participate in school garden education in the future, and 81.2% answered that they would like to participate in school garden education in the future. Conclusion The creation and utilization of school gardens is expected to continue to increase due to the diverse values and social atmospheres of school gardens, and this study provides policy data to vitalize school garden education in the future.
Semantic Network Analysis of Newspaper Articles related to Agro-healing
Authors: Park Yumin , Shin Yong-Wook
Published: May 2022

Background and objective Despite the fact that the COVID-19 pandemic has increased the demand for mental health services, access has been limited, resulting in service gaps and severance. Agro-healing, which is expected to be utilized successfully to promote mental health for both individuals and communities, could be a solution. This study was conducted to provide basic data for revitalizing policies and research related to agro-healing by analyzing the trends in big data of online news articles over the last decade. Methods A total of 2,310 news articles related to agro-healing were collected from January 1, 2012 to December 31, 2021 by crawling Naver News. To extract nouns with practical meaning, the Okt morphological analysis of the KoNLPy module in Python 3.9 was employed. Semantic network analysis was conducted to validate degree centrality, betweenness centrality, and eigenvector centrality in order to understand the centrality and connectivity of significant keywords. The data was visualized using Gephi 0.9.2 by performing CONCOR analysis to generate clusters. Results The keywords with the highest degree centrality were agro-healing, followed by healing, care farm, vitality, RDA, citizens, and rural tourism. Agro-healing, Healing, stress, urban, disabilities, care farm, dementia, and rural area were highest in terms of betweenness centrality. The eigenvector centrality was highest in agro-healing, followed by vitality, healing, care farm, and effect. As a result of the CONCOR analysis, four clusters were identified: ‘agro-healing characteristics’, ‘agro-healing resources’, ‘agro-healing activities’, and ‘agro-healing target and effect’. Conclusion According to the findings, social expectations and need for agro-healing to improve public health became a significant part of the discourses. This research is expected to help determine future research and policy directions, as the vitality of agro-healing continues to provide national welfare services and seek sustainable growth in agricultural and rural areas.
Harpochilus corrugatus (Acanthaceae), a new and endangered chiropterophylous species from the highlands of central-southern Bahia, Brazil
Authors: SILVA FABIO ARAÚJO , ALBUQUERQUE-LIMA SINZINANDO , TAYLOR NIGEL P. , ZAPPI DANIELA C.
Published: May 2022

During floral biology studies in Northeastern Brazil, populations of Harpochilus from central-southern Bahia have been found to differ from H. neesianus. Following extensive fieldwork and floral visitor observations, studies of all available specimens, coupled with micromorphology of indumentum and pollen, we have gathered sufficient evidence to recognize these populations as distinct and a new species. H. corrugatus is hereby described and illustrated. Harpochilus corrugatus differs from its closest ally, H. neesianus, by having sessile, corrugate, deltoid leaves and yellow flowers with a brownish-purple hue. A distribution map and identification key to distinguish the three species of the genus are presented, and the IUCN category of threat for the new species was assessed as Endangered. Glossophaginae bats were observed to be the floral visitor, suggesting that this is another bat-pollinated species of that genus from the Caatinga biome.
Two new Staurosirella species (Staurosiraceae, Bacillariophyta) observed in an historic Rabenhorst sample
Authors: VAN DE VIJVER BART
Published: May 2022

During a survey of some exsiccata samples from Rabenhorst’s Die Algen Sachen’s und Europa’s, two Staurosirella taxa that could not be identified using the currently available literature were observed in a sample from the Swiss Alps, collected in 1863 CE. The two taxa occurred together with a large population of S. neopinnata and were studied using detailed light and scanning electron microscopy. Based on the obtained observations on their morphology, and after comparing both taxa with all currently known Staurosirella and some Staurosira species, both are described as new. Staurosirella coutelasiana Van de Vijver sp. nov. is characterized in having a linear-lanceolate to lanceolate, isopolar valve outline with small apical pore fields on both apices. The second new species, S. minutissima Van de Vijver sp. nov., is a small-celled Staurosirella species and possesses short lineolae, an almost flat valve surface and small apical pore fields. Both species are extensively illustrated and discussed. Their ecological preferences are derived from the associated diatom flora in the sample and point to oligotrophic, calcium-carbonate rich, oligosaprobic conditions.
A new species of Conognatha (Pithiscus) from Minas Gerais State in Brazil (Coleoptera: Buprestidae)
Authors: PINEDA CRISTIAN R. , KOIKE RICARDO M. , BARROS RAFAEL C.
Published: May 2022

Conognatha (Pithiscus) continua Pineda, Koike & Barros sp. nov. (Coleoptera: Buprestidae: Stigmoderini), from southeast Brazil is described and illustrated. A simplified identification key for the Conognatha (P.) continua species-group is proposed.
Treatment and Nursing Role in Coronary Heart Disease and Phylogenetic Analysis of a Novel Compound Extracted from Populus ilicifolia
Authors: Wang Hong-Ying , Zhang Ling
Published: May 2022

Cardiovascular disease, the top killer endangering human health, has spread worldwide and is a major disaster in many countries. Populus ilicifolia has attracted the interest of researchers owing to the various biological activities of its different secondary metabolites. Therefore,
in this research, the important role of a new compound extracted from P. ilicifolia in coronary heart disease (CHD) treatment and nursing was explored, and its associated mechanism was analyzed. An animal model of CHD was constructed. After treatment with the compound, the levels of
inflammatory cytokines that were released into plasma were tested through ELISA. Real-time RT-PCR was carried out to test the activation of the NF-κB signaling pathway. The genetic relationship between P. ilicifolia and other tree species was also explored on the basis
of the chloroplast genome.
Polydopamine Nanoparticles Loaded with EPB41L4A-AS2 Promote Ovarian Cancer Cell Apoptosis Through Activation of Mitogen-Activated Protein Kinase Signaling Pathway
Authors: Wu Xiao-Ying , Xing Xue-Feng , An Ming
Published: May 2022

Ovarian cancer (OC) is one of known gynecologic malignant tumors, posing a serious threat to women’s life, and this disorder is often not diagnosed until it’s more advanced. This study aimed to identify the efficacy of polydopamine (PDA) nanoparticles loaded with EPB41L4A-AS2
(EPB) on OC. PDA nanoparticles-loaded EPB (PDA-EPB) were prepared, and OC cells were administrated with 10 μmol/LPDA-EPB nanoparticles or 10 μmol LHBSS buffer (control group). Untreated cells were taken as control group, and CCK-8 assay was conducted 24 h after treatments,
to detect cell proliferation, while Transwell assay was used to detect invasion. Apoptosis was evaluated by flow cytometry along with analysis of Bax, Bcl-2, and caspase-3 apoptosis genes expression as well as the expression of Erk1/2, JNK, and p38 proteins. PDA-EPB nanomaterials presented
uniform nanoparticle size of 100 nm and hydrated particle size of 190 nm. Treatment with composite nanoparticles decreased proliferation of OC cells over time. The increased concentration of nanoparticles occurred with decreased proliferation activity and 10 μmol/L was the best intervention
concentration. Besides, PDA-EPB nanomaterials resulted in decreased number of invaded and migrated cells (41.03±3.95%) and increased apoptosis rate (33.59±3.23%), compared with the other two groups. The apoptosis ability was significantly higher, P < 0.05. Meanwhile,
in the presence of PDA-EPB nanoparticles, the experimental group presented low expressions of Bad (1.96 ±0.23), Bcl-2 (1.56± 0.34), Caspase-3 (2.89± 0.28) and (0.98 ±0.39), JNK (0.53±0.31), and p38 (0.79±0.26). PDA-EPB nanoparticles therefore decreased
cell proliferation and induced apoptosis through specifically binding to the MAPK signaling pathway to activate the expression of Erk1/2, JNK, and p38 in OC.
Standing on the Shoulders of Giants: Leveraging Management Research on Grand Challenges
Authors: Dorado Silvia , Antadze Nino , Purdy Jill , Branzei Oana
Published: May 2022

We advance research on how businesses engage with the complex social problems currently known as Grand Challenges. We study the concepts that preceded the term Grand Challenges, the connected ontologies that ground them, and the diversity of perspectives they offered. We construct a knowledge map that includes well-researched obstacles, such as governance obstacles hindering engagement and sensemaking obstacles limiting the ideation of novel and creative efforts. But we also build on prior research to identify curation obstacles, which precede engagement and define which problems receive social attention, and adaptation obstacles, which create uncertainty over workable solutions and bias the momentum of social systems toward the status quo. Our broader view on the obstacles defining Grand Challenges opens new pathways and identifies underexplored levers by which to understand and influence business engagement with complex social problems.
International Students who Became U.S. Counseling Psychology Faculty Members: A Collaborative Autoethnography
Authors: Consoli Andrés J. , Çiftçi Ayşe , Poyrazlı Şenel , Iwasaki Michiko , Canetto Silvia Sara , Ovrebo Elin , Wang Chiachih D. C. , Forrest Linda
Published: May 2022

International students have a considerable presence in U.S. counseling psychology programs; what happens when they pursue academic counseling psychology positions in U.S. institutions? Seven counseling psychology faculty who started as international students in the United States used collaborative autoethnography to examine this matter. We found that our identification with counseling psychology philosophy and our lifelong, self-reflective process as cultural insiders/outsiders have proven crucial. Likewise, we found that our academic career development has been shaped by extra challenges encountered when dealing with ethnocentric aspects of U.S. psychology and by unique opportunities generated by our multinational professional identities and multilingual abilities. Three themes recurred across our reflections: Overcoming Linguistic Differences, Learning to Thrive Across Cultures, and Mentoring as a Valued Experience. We offer advice for international counseling students considering careers in U.S. academia and discuss the implications of our findings for research, training, and advocacy.
“Infrastructuring” Pleasure: Montjuïc Before and After the Lights of the 1929 Barcelona International Exhibition
Authors: Castro-Varela Aurelio
Published: May 2022

Montjuïc is a long flat-topped hill overlooking the harbor of Barcelona from the southeast border of the city. From 1915 onwards, it underwent a profound transformation turning it into the site of the 1929 International Exhibition. This article revolves around this turning point, examining the aesthetic role of infrastructures in delivering pleasure on the hill before and during the dazzling, monumental display that characterized the event. The sociocultural practices at play in Montjuïc before its re-urbanization are thus recalled and considered in terms of their environmental and bodily features, utterly different from the visual journey later offered within and around the Exhibition venue. I delve into these two regimes of pleasure by theorizing their material forms as functional to and expressive of specific ways of having fun. Consequently, this enquiry concerns the ambient conditions, sensorial landscapes and architectural elements through which pleasure took shape in Montjuïc from the mid-nineteenth century to 1936.
Reporting Interaction Effects: Visualization, Effect Size, and Interpretation
Authors: Murphy Kevin R. , Aguinis Herman
Published: May 2022

Most management theories include hypotheses about interaction effects (i.e., the relation between two variables depends on values of another), but it is common for articles to present results that make it difficult to evaluate the nature, strength, and importance of the effect. We offer recommendations for improving the reporting of interaction effects by focusing on (a) visualizations, (b) effect size estimates, and (c) assessments of the nature, meaning, and importance of interactions for theory and practice.