bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Elevated Homocysteine and Metabolic Syndrome in a Community-Dwelling Middle-Aged and Elderly Population in Taiwan
Authors: Shih Yu-Lin , Shih Chin-Chuan , Huang Tzu-Cheng , Chen Jau-Yuan
Published: January 2023

(1) Background: Metabolic syndrome has become a serious health problem in society. Homocysteine is a biomarker for cardiovascular disease. We investigated the relationship between homocysteine levels and metabolic syndrome. (2) Methods: A total of 398 middle-aged and elderly individuals were included in our study. First, we divided the participants into two groups: the metabolic syndrome group and the nonmetabolic syndrome group. Second, according to tertiles of homocysteine levels from low to high, the participants were divided into first, second, and third groups. Pearson’s correlation was then calculated for homocysteine levels and metabolic factors. Scatterplots are presented. Finally, the risk of metabolic syndrome in the second and third groups compared with the first group was assessed by multivariate logistic regression. (3) Results: In our study, the metabolic syndrome group had higher homocysteine levels, and the participants in the third group were more likely to have metabolic syndrome. Multivariate logistic regression revealed that the third group, which had the highest homocysteine level, was associated with metabolic syndrome with an odds ratio of 2.32 compared with the first group after adjusting for risk factors. (4) Conclusions: We concluded that high plasma homocysteine levels were independently associated with MetS in our study population.
A Lymph Node Ratio Model for Prognosis of Patients with Pancreatic Neuroendocrine Tumors
Authors: Osher Esther , Shalabna Eiman , Klausner Joseph M. , Greenman Yona , Stern Naftali , Shibolet Oren , Scapa Erez , Yakir Oz , Shor Dana Ben-Ami , Bar-Yishay Iddo , Shamai Sivan , Sofer Yael , Lubezky Nir , Goykhman Yaacov , Lahat Guy , Wolf Ido , Pelles Sharon , Aizic Asaf , Blachar Arye , Geva Ravit
Published: January 2023

The objective of this study was to determine the prognostic value of lymph node (LN) involvement and the LN ratio (LNR) and their effect on recurrence rates and survival in patients with pancreatic neuroendocrine tumors (PNETs) undergoing surgery. This single-center retrospective study reviewed the medical records of 95 consecutive patients diagnosed with PNETs who underwent surgery at our medical center between 1997 and 2017. The retrieved information included patient demographics, pathology reports, treatments, and oncological outcomes. Results: 95 consecutive potentially suitable patients were identified. The 78 patients with PNETs who underwent surgery and for whom there was adequate data were included in the analysis. Their mean ± standard deviation age at diagnosis was 57.4 ± 13.4 years (range 20–82), and there were 50 males (64%) and 28 females (36%). 23 patients (30%) had LN metastases (N1). The 2.5- and 5-year disease-free survival (DFS) rates for the entire cohort were 79.5% and 71.8%, respectively, and their 2- and 5-year overall survival (OS) rates were 85.9% and 82.1%, respectively. The optimal value of the LNR was 0.1603, which correlated with the outcome (2-year OS p = 0.002 HR = 13.4 and 5-year DFS p = 0.016 HR = 7.2, respectively, and 5-year OS and 5-year DFS p = 0.004 HR = 9 and p = 0.001 HR = 10.6, respectively). However, the multivariate analysis failed to show that the LNR was an independent prognostic factor in PNETs. Patients with PNETs grade and stage are known key prognostic factors influencing OS and DFS. According to our results, LNR failed to be an independent prognostic factor.
Long-Interval Intracortical Inhibition and the Cortical Silent Period in Youth
Authors: Ahern Kelly B. , Garzon Juan F. , Yuruk Deniz , Saliba Maria , Ozger Can , Vande Voort Jennifer L. , Croarkin Paul E.
Published: January 2023

Background: The cortical silent period (CSP) and long-interval intracortical inhibition (LICI) are putative markers of γ-aminobutyric acid receptor type B (GABAB)-mediated inhibitory neurotransmission. We aimed to assess the association between LICI and CSP in youths. Methods: We analyzed data from three previous studies of youth who underwent CSP and LICI measurements with transcranial magnetic stimulation and electromyography. We assessed CSP and LICI association using Spearman rank correlation tests and multiple linear regression analyses adjusted for demographic and clinical covariates. Results: The sample included 16 healthy participants and 45 participants with depression. The general mean (SD) age was 15.5 (1.7), 14.3 (1.7) for healthy participants, and 15.9 (1.6) years for participants with depression. Measures were nonnormally distributed (Shapiro–Wilk, p < 0.001). CSP and LICI were not correlated at 100-millisecond (ρ = −0.2421, p = 0.06), 150-millisecond (ρ = −0.1612, p = 0.21), or 200-millisecond (ρ = −0.0507, p = 0.70) interstimulus intervals using Spearman rank correlation test. No correlations were found in the multiple regression analysis (p = 0.35). Conclusions: Although previous studies suggest that cortical silent period and long-interval intracortical inhibition measure GABAB receptor-mediated activity, these biomarkers were not associated in our sample of youths. Future studies should focus on the specific physiologic and pharmacodynamic properties assessed by CSP and LICI in younger populations.
Enhanced Coloration Time of Electrochromic Device Using Integrated WO3@PEO Electrodes for Wearable Devices
Authors: Kwon Haneul , Kim Soohyun , Ham Mirim , Park Yewon , Kim Haekyoung , Lee Wonmok , Lee Hyunjung
Published: January 2023

Electrochromic technologies that exhibit low power consumption have been spotlighted recently. In particular, with the recent increase in demand for paper-like panel displays, faster coloration time has been focused on in researching electrochromic devices. Tungsten trioxide (WO3) has been widely used as an electrochromic material that exhibits excellent electrochromic performance with high thermal and mechanical stability. However, in a solid film-type WO3 layer, the coloration time was long due to its limited surface area and long diffusion paths of lithium ions (Li-ions). In this study, we attempted to fabricate a fibrous structure of WO3@poly(ethylene oxide) (PEO) composites through electrospinning. The fibrous and porous layer showed a faster coloration time due to a short Li-ion diffusion path. Additionally, PEO in fibers supports Li-ions being quickly transported into the WO3 particles through their high ionic conductivity. The optimized WO3@PEO fibrous structure showed 61.3 cm2/C of high coloration efficiency, 1.6s fast coloration time, and good cycle stability. Lastly, the electrochromic device was successfully fabricated on fabric using gel electrolytes and a conductive knitted fabric as a substrate and showed a comparable color change through a voltage change from −2.5 V to 1.5 V.
Eu2O3@Cr2O3 Nanoparticles-Modified Carbon Paste Electrode for Efficient Electrochemical Sensing of Neurotransmitters Precursor L-DOPA
Authors: Mijajlović Aleksandar , Ognjanović Miloš , Manojlović Dragan , Vlahović Filip , Đurđić Slađana , Stanković Vesna , Stanković Dalibor
Published: January 2023

There are ten million people in the world who have Parkinson’s disease. The most potent medicine for Parkinson’s disease is levodopa (L-DOPA). However, long-term consumption of L-DOPA leads to the appearance of side effects, as a result of which the control and monitoring of its concentrations are of great importance. In this work, we have designed a new electrochemical sensor for detecting L-DOPA using a carbon paste electrode (CPE) modified with Eu2O3@Cr2O3 composite nanoparticles. Rare earth elements, including Eu, are increasingly used to design new electrode nanocomposites with enhanced electrocatalytic properties. Europium has been considered a significant lanthanide element with greater redox reaction behavior. We conducted a hydrothermal synthesis of Eu2O3@Cr2O3 and, for the first time, the acquired nanoparticles were used to modify CPE. The proposed Eu2O3@Cr2O3/CPE electrode was investigated in terms of its electrocatalytic properties and then used to develop an analytical method for detecting and quantifying L-DOPA. The proposed sensor offers a wide linear range (1–100 µM), high sensitivity (1.38 µA µM−1 cm−2) and a low detection limit (0.72 µM). The practical application of the proposed sensor was investigated by analyzing commercially available pharmaceutical tablets of L-DOPA. The corresponding results indicate the excellent potential of the Eu2O3@Cr2O3/CPE sensor for application in real-time L-DOPA detection.
Online Inspection of Browning in Yali Pears Using Visible-Near Infrared Spectroscopy and Interpretable Spectrogram-Based CNN Modeling
Authors: Hao Yong , Li Xiyan , Zhang Chengxiang , Lei Zuxiang
Published: January 2023

Browning is the most common physiological disease of Yali pears during storage. At the initial stage, browning only occurs in the tissues near the fruit core and cannot be detected from the appearance. The disease, if not identified and removed in time, will seriously undermine the quality and sale of the whole batch of fruit. Therefore, there is an urgent need to explore a method for early diagnosis of the browning in Yali pears. In order to realize the dynamic and online real-time detection of the browning in Yali pears, this paper conducted online discriminant analysis on healthy Yali pears and those with different degrees of browning using visible-near infrared (Vis-NIR) spectroscopy. The experimental results show that the prediction accuracy of the original spectrum combined with a 1D-CNN deep learning model reached 100% for the test sets of browned pears and healthy pears. Features extracted by the 1D-CNN method were converted into images by Gramian angular field (GAF) for PCA visual analysis, showing that deep learning had good performance in extracting features. In conclusion, Vis-NIR spectroscopy combined with the 1D-CNN discriminant model can realize online detection of browning in Yali pears.
Salivary Glucose Detection with Laser Induced Graphene/AgNPs Non-Enzymatic Sensor
Authors: Aparicio-Martínez Eider Pedro , Vega-Rios Alejandro , Osuna Velia , Dominguez Rocio Berenice
Published: January 2023

The tailoring of novel nanomaterials for sensitive glucose detection through a non-enzymatic mechanism is currently under intensive research. Here, we present a laser-induced graphene (LIG) electrode decorated with silver nanoparticles (AgNPs) as a catalytic element for the direct electrooxidation of glucose. The AgNPs were synthesized through cyclic voltammetry using LIG as a template, resulting in a porous tridimensional assembly with anchored nanostructures. The characterization corroborated the formation of LIG/AgNPs composite with distinctive peaks attributed to Ag2O and AgO interaction with glucose. The proposed non-enzymatic sensors were successfully applied for non-enzymatic amperometric detection, exhibiting a linear range from 1 to 10 mM in the first peak (+0.7 V) and a narrow range from 1 to 2 mM with higher sensitivity of 52.2 mA/mM and improved LOD of 45 μM in the second peak (+0.55 V). The applicability of the LIG/AgNPs sensor was evaluated with spiked artificial saliva in a PoC format using a smartphone potentiostat, showing an average recovery rate of 91%. The analysis was performed in a portable, mobile, and low-cost fashion using a simulated non-invasive sample, with promising results in clinical ranges.
The Role of Beta-Endorphin in Food Deprivation-Mediated Increases in Food Intake and Binge-Eating
Authors: Tolentino Laica , Iqbal Asif , Rahman Shafiqur , Lutfy Kabirullah
Published: January 2023

Food deprivation and binge eating represent significant public health concerns. Previous studies have implicated that hypothalamic opioids are affected following food deprivation. However, the role of each opioid peptide is not fully understood. Therefore, we investigated the role of endogenous beta-endorphin in food deprivation-mediated increases in food intake and binge eating. Male mice lacking beta-endorphin and their respective controls were subjected to 24 h food deprivation and then were randomly assigned to receive a regular diet (RD) or a high-fat diet (HFD). After four to five weeks, animals were re-exposed to an HFD to assess if previous exposure to HFD would enhance binge-eating behavior. We report that food deprivation significantly increases food intake; however, beta-endorphin may not be involved in this process. In addition, our findings suggest that prior exposure to an HFD promotes binge-eating behavior in wildtype mice, and that these effects were modestly decreased in beta-endorphin knockout mice. Overall, our results support that beta-endorphin may play a modest role in mediating palatability-driven feeding, but not hunger-associated feeding. A better understanding of neural mechanisms involved in binge eating and deprivation-induced increases in food intake may inspire new prevention or treatment options to decrease the burden of eating disorders.
Maximal Safe Resection in Glioblastoma Surgery: A Systematic Review of Advanced Intraoperative Image-Guided Techniques
Authors: Bonosi Lapo , Marrone Salvatore , Benigno Umberto Emanuele , Buscemi Felice , Musso Sofia , Porzio Massimiliano , Silven Manikon Poullay , Torregrossa Fabio , Grasso Giovanni
Published: January 2023

Glioblastoma multiforme (GBM) represents the most common and aggressive central nervous system tumor associated with a poor prognosis. The aim of this study was to depict the role of intraoperative imaging techniques in GBM surgery and how they can ensure the maximal extent of resection (EOR) while preserving the functional outcome. The authors conducted a systematic review following PRISMA guidelines on the PubMed/Medline and Scopus databases. A total of 1747 articles were identified for screening. Studies focusing on GBM-affected patients, and evaluations of EOR and functional outcomes with the aid of advanced image-guided techniques were included. The resulting studies were assessed for methodological quality using the Risk of Bias in Systematic Review tool. Open Science Framework registration DOI 10.17605/OSF.IO/3FDP9. Eighteen studies were eligible for this systematic review. Among the selected studies, eight analyzed Sodium Fluorescein, three analyzed 5-aminolevulinic acid, two evaluated IoMRI imaging, two evaluated IoUS, and three evaluated multiple intraoperative imaging techniques. A total of 1312 patients were assessed. Gross Total Resection was achieved in the 78.6% of the cases. Follow-up time ranged from 1 to 52 months. All studies assessed the functional outcome based on the Karnofsky Performance Status scale, while one used the Neurologic Assessment in Neuro-Oncology score. In 77.7% of the cases, the functional outcome improved or was stable over the pre-operative assessment. Combining multiple intraoperative imaging techniques could provide better results in GBM surgery than a single technique. However, despite good surgical outcomes, patients often present a neurocognitive decline leading to a marked deterioration of the quality of life. Advanced intraoperative image-guided techniques can allow a better understanding of the anatomo-functional relationships between the tumor and the surrounding brain, thus maximizing the EOR while preserving functional outcomes.
Evaluation of High Intracranial Plaque Prevalence in Type 2 Diabetes Using Vessel Wall Imaging on 7 T Magnetic Resonance Imaging
Authors: Shozushima Masaharu , Mori Futoshi , Yashiro Satoshi , Todate Yusuke , Oda Tomoyasu , Nagasawa Kan , Hasegawa Yutaka , Takebe Noriko , Sasaki Makoto , Ishigaki Yasushi
Published: January 2023

Background: While type 2 diabetes (T2D) is a major risk for ischemic stroke, the associated vessel wall characteristics remain essentially unknown. This study aimed to clarify intracranial vascular changes on three-dimensional vessel wall imaging (3D-VWI) using fast spin echo by employing 7Tesla (7T) magnetic resonance imaging (MRI) in T2D patients without advanced atherosclerosis as compared to healthy controls. Methods: In 48 T2D patients and 35 healthy controls, the prevalence of cerebral small vessel diseases and intracranial plaques were evaluated by 3D-VWI with 7T MRI. Results: The prevalence rate of lacunar infarction was significantly higher in T2D than in controls (n = 8 in T2D vs. n = 0 in control, p = 0.011). The mean number of intracranial plaques in both anterior and posterior circulation of each subject was significantly larger in T2D than in controls (2.23 in T2D vs. 0.94 in control, p < 0.01). In T2D patients, gender was associated with the presence of intracranial plaques. Conclusion: This is the first study to demonstrate the high prevalence of intracranial plaque in T2D patients with neither confirmed atherosclerotic disease nor symptoms by performing intracranial 3D-VWI employing 7TMRI. Investigation of intracranial VWI with 7T MRI is expected to provide novel insights allowing early intensive risk management for prevention of ischemic stroke in T2D patients.
Sporadic Spinal-Onset Amyotrophic Lateral Sclerosis Associated with Myopathy in Three Unrelated Portuguese Patients
Authors: Oliveira Santos Miguel , Gromicho Marta , Pronto-Laborinho Ana , de Carvalho Mamede
Published: January 2023

Amyotrophic lateral sclerosis (ALS) and myopathy have been already described as part of a common genetic syndrome called multisystem proteinopathy. They may occur together or not, and can be associated with other clinical features such as frontotemporal dementia and Paget’s bone disease. In addition, primary skeletal muscle involvement has been also reported in inherited forms of lower motor neuron disease, in spinal–bulbar muscular atrophy and in spinal muscular atrophy. We aim to characterize three sporadic, spinal-onset ALS patients, one with a concurrent non-specific myopathy, and two with a previous diagnosis of myopathy before upper and lower motor neuron signs emerged. Perhaps our sporadic ALS cases associated with myopathy share a common, but still unknown, pathogenic background. These cases raise the paradigm of a possible interplay between skeletal muscle degeneration and motor neuron damage.
Anatomical Variations of the Common Carotid Arteries and Neck Structures of the New Zealand White Rabbit and Their Implications for the Development of Preclinical Extracranial Aneurysm Models
Authors: Boillat Gwendoline , Franssen Tim , Wanderer Stefan , Rey Jeannine , Casoni Daniela , Andereggen Lukas , Marbacher Serge , Gruter Basil E.
Published: January 2023

Background: Rabbit models involving neck arteries are of growing importance for the development of preclinical aneurysm models. An optimal understanding of the anatomy is primordial to allow the conception of models while minimizing mortality and morbidity. The aim of this study is to give reliable anatomical landmarks to allow a standardized approach to the neck vessels. Methods: We performed a necropsy on nine specimens from ongoing experimental studies. We measured the distance between the origins of the right and left common carotid artery (rCCA/lCCA) and between the rCCA and the manubrium sterni (MS). The structures at risk were described. Results: Female New Zealand White rabbits (NZWR) weighing 3.7 ± 0.3 kg and aged 25 ± 5 weeks were included. The rCCA origin was located 9.6 ± 1.2 mm laterally and 10.1 ± 3.3 mm caudally to the MS. In all specimens, the lCCA originated from the aortic arch, together with the brachiocephalic trunk (BCT), and 6.2 ± 3.1 mm proximally to the rCCA origin. The external and internal jugular veins, trachea and laryngeal nerve were the main structures at risk. Conclusions: The data help to localize both CCAs and their origin to guide surgical approaches with the manubrium sterni as a main landmark. Special attention has to be paid to the trachea, jugular veins and laryngeal nerves.
How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research
Authors: Grant Shara S. , Kim Kye , Friedman Bruce H.
Published: January 2023

Caffeine substantially affects cardiovascular functioning, yet wide variability exists in caffeine control procedures in cardiovascular reactivity research. This study was conducted in order to identify a minimal abstention duration in habitual coffee consumers whereby cardiovascular reactivity is unconfounded by caffeine; Six hours (caffeine’s average half-life) was hypothesized. Thirty-nine subjects (mean age: 20.9; 20 women) completed a repeated measures study involving hand cold pressor (CP) and memory tasks. Caffeinated and decaffeinated coffee were administered. The following cardiovascular indices were acquired during pre-task, task, and post-task epochs prior to coffee intake, 30 min-, and six hours post-intake: Heart rate (HR), high-frequency heart rate variability (HF-HRV), root mean squared successive differences (RMSSD), systolic and diastolic blood pressures (SBP, DBP), mean arterial pressure (MAP), pre-ejection period (PEP), left ventricular ejection time (LVET), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI). Results support the adequacy of a six-hour abstention in controlling for caffeine-elicited cardiovascular changes. The current study offers a suggested guideline for caffeine abstention duration in cardiovascular research in psychophysiology. Consistent practice in caffeine abstention protocols would promote validity and reliability across such studies.
Navigated Transcranial Magnetic Stimulation Motor Mapping and Diffusion Tensor Imaging Tractography for Diencephalic Tumor in Pediatric Patients
Authors: Baro Valentina , Sartori Luca , Caliri Samuel Luciano , Furlanis Giulia Melinda , D’Amico Alberto , Meneghini Giulia , Facchini Silvia , Ferreri Florinda , Corbetta Maurizio , Denaro Luca , Landi Andrea
Published: January 2023

Background. In deep-seated brain tumors, adequate preoperative planning is mandatory to assess the best surgical corridor to obtain maximal safe resection. Functional diffusor tensor imaging (DTI) tractography based on navigated transcranial magnetic stimulation (nTMS) motor mapping has proven to be a valid preoperative examination method in adults. The aim of this paper is to present the application of nTMS and functional DTI tractography in a series of pediatric diencephalic tumors. Material and methods. Three patients affected by thalamic (one) and thalamopeduncular tumor (two) were successfully examined with nTMS motor mapping and DTI tractography between October 2020 and October 2021 (F:M 3:0, mean age 12 years ± 0.8). Cortical representation of leg, hand and mouth were determined in the affected hemisphere and the positive stimulation spots were set as seeds point for tractography. Results. Mapping of the motor cortex and tracts reconstruction for leg and hand were successful in all patients, while facial function was properly mapped in one patient only. In all cases, the procedure was well tolerated and no adverse events were recorded. Spatial relationships between tumor and functional tissue guided the surgical planning. Extent of the resection varied from 96.1% to 100% with a postoperative new motor deficit in one patient. Conclusions. nTMS and DTI fiber tracking is a feasible, effective and well-tolerated method to identify motor pathway in deep-seated lesion in pediatric population.
The Psychosocial Risks and Impacts in the Workplace Assessment Tool: Construction and Psychometric Evaluation
Authors: Roussos Petros L.
Published: January 2023

Psychosocial risks constitute one of the major contemporary challenges for occupational health and safety. As early identification is the first step towards psychosocial risk management, the psychometric tool presented in the paper has been constructed in order to measure psychosocial risks as well as their impacts. The Psychosocial Risks and Impacts in the Workplace Assessment Tool (PRIWA) has been developed in Greek during the early years of the economic crisis. The paper presents the tool and the studies that were conducted to evaluate its psychometric characteristics. Six large samples of employees from many different Greek companies were administered the PRIWA and other tools. The results of the exploratory factor analysis demonstrated a seven-factor structure of the PRIWA, which was later confirmed by confirmatory factor analysis. Analyses were also performed to test internal consistency, item-to-scale homogeneity, and concurrent validity of the PRIWA. The results indicated that PRIWA is a reliable and valid psychometric tool, which gives its users the opportunity to conduct research, develop prevention plans, and/or design customized interventions.
Poor School Academic Performance and Benign Epilepsy with Centro-Temporal Spikes
Authors: Vetri Luigi , Pepi Annamaria , Alesi Marianna , Maltese Agata , Scifo Lidia , Roccella Michele , Quatrosi Giuseppe , Elia Maurizio
Published: January 2023

Background: Poor academic performance of students with epilepsy seems to be a multifactorial problem related to difficulties in reading, writing, math, and logic skills. Poor school and academic performances refer to learning problems in a specific academic area due to learning disorders and learning difficulties not excluding the ability to learn in a different manner during school and academic life. Sometimes, school, academic difficulties, and Rolandic epilepsy can coexist together, and there may be comorbidities. Consequently, the risk of impaired academic performance in people with epilepsy is high. Methods: This review analyzed the relationship between Benign Epilepsy with Centro-Temporal Spikes (BECTS) and poor school and academic performance (PSAP) in children and adolescents (aged 6 to 19), and in adults (aged 20 to no age limit). The PRISMA guideline was used to guide our review strategy. Results: This research shows that Benign Epilepsy with Centro-Temporal Spikes (BECTS) and poor school and academic performances are strongly correlated. An early onset age, as well as a long persistence of seizures, correlate more closely with PSAP. On the other hand, it appears that good pharmacological control of seizures and remission from the acute phase of the pathology support better school performance. Conclusions: This review highlights how neuropsychological aspects are also involved in patients with BECTS and PSAP, both in the greater predisposition to the establishment of other neuropsychiatric conditions and in the possibility that stigma conditions and poor academic results may have repercussions on the adaptation and functioning of these subjects. Global management of the subject with BECTS and PSAP is essential, which also pays attention to the aspects of social and scholastic inclusion, both to achieve age-appropriate educational and behavioral objectives, to give the necessary tools for the growth of the individual, and to allow a serene transition to adulthood, favoring autonomous learning and better outcomes.
Transformational Change and Digitalization—The Case of the Swedish Road and Transport Administration
Authors: Molin Fredrik , Norrman Brandt Eva
Published: January 2023

Background: Digitalization is one of the drivers of change in both public and private organizations. It is therefore relevant to understand how a government agency like the Swedish Transport Administration manage and experience change. Methods: In this qualitative study, interviews (n = 15) with respondents with insight and connection to digitalization and change highlight factors related to digitalization and change-capacity within the agency. Results: The results of the interviews are presented in a thematic analysis. Five themes were identified: Digitalization, management control, stability requirements, organizational culture, and lack of a comprehensive view. The research literature in the field of change creates a fund for a discussion about the Administration’s situation regarding digitalization, development, and transformational change. Conclusions: The results indicate that the Transport Administration still has a long way to travel in terms of organizational readiness for change. To address this issue, the Transport Administration should prioritize the development and implementation of a comprehensive change management strategy including clear communication, active engagement, and participation from all employees, and a focus on building a culture of adaptability and continuous improvement.
How Outstanding Universal Value Attractiveness and Tourism Crowding Affect Visitors’ Satisfaction?
Authors: Nian Sifeng , Chen Min , Zhang Xiaowan , Li Donghe , Ren Jingya
Published: January 2023

A World Heritage Site is a masterpiece of mankind and/or nature that possesses outstanding universal value (OUV). In this regard, the 5Cs strategic objectives (credibility, communication, capacity-building, conservation, and community) set by the World Heritage Committee have become a main issue for WHS sustainable development. As one of the key stakeholders of WHS, tourist’s perceived OUV attractiveness, congestion, and attitudinal behavior have significant implications for heritage protection and tourism’s sustainable development. Based on the perspectives of OUV attractiveness and perceived tourist crowding, and taking into account destination attachment, the influencing factors and mechanisms of tourist satisfaction are investigated. In view of the 536 questionnaire responses from tourists of Mount Sanqingshan National Park, the structural equation modeling approach was employed to study tourist satisfaction. The conclusions were sketched: (1) tourist crowding perception did not have a significant negative effect on OUV attractiveness; destination attachment, and tourist satisfaction, and the degree of crowding perception was low; (2) the OUV attractiveness has a significant positive influence on destination attachment and tourist satisfaction, which fully highlights the charm of OUV and its important role in shaping tourists’ attitudes/behaviors; (3) destination attachment has a significant positive effect on tourist satisfaction, indicating that tourists’ heritage-place attachment contributes to tourist satisfaction. Finally, the analysis of tourism crowding, OUV, and the satisfaction framework proposed broaden the horizons of visitor satisfaction research, which is also a positive response to the strategic objectives of the 5Cs of WHS, with some practical implications for heritage preservation and visitor management in World Heritage Sites.
Contributions of Multilevel Family Factors to Emotional and Behavioral Problems among Children with Oppositional Defiant Disorder in China
Authors: He Ting , Meza Jocelyn , Ding Wan , Hinshaw Stephen P. , Zhou Qing , Akram Umair , Lin Xiuyun
Published: January 2023

Oppositional defiant disorder (ODD) is one of the most prevalent childhood mental health disorders and is extremely affected by family factors. However, limited studies have addressed the issue from the perspective of family systems. The current study examines the associations between multilevel family factors (i.e., family cohesion/ adaptability at system level, mother–child and father–child attachment at a dyadic level, and child self-esteem at an individual level) and emotional and behavioral problems among children with ODD in China. The participants were 256 Chinese children with ODD and their parents and class master teachers. A multiple-informant approach and structural equation model were used. The results revealed that system level factors (family cohesion/adaptability) were associated with child emotional and behavior problems indirectly through factors at the dyadic level (mother–child attachment) and the individual level (child self-esteem) in sequence. Mother–child, but not father–child, attachment, mediated the linkage between family cohesion/adaptability and the emotional problems of children with ODD. Moreover, child self-esteem mediated the association between mother–child attachment and child emotional and behavioral problems. The findings of the present study underscored that multilevel family factors are uniquely related to emotional and behavioral problems in children with ODD.
Effects of Investment Experience on the Stock Investment Task: The Mediating Role of Risk Perception
Authors: Li Zewei , Wu Qi , Hong Pengfei , Tian Runzhi
Published: January 2023

Due to the limitations of traditional financial analysis and the non-specificity of laboratory-based gambling tasks, it is difficult for researchers to isolate the independent contributions of risk perception and initial investment experience on novice investors’ behaviors. Thus, it is still necessary for researchers to describe the process by which investment experience affects the investment behavior of novice investors by employing the methods of psychological experiments that can control and eliminate these confounding variables in the laboratory. The current study created a stock investment task based on the balloon analogy risk task to simulate the stock market in the laboratory. Two hundred and twenty Chinese college students were recruited as participants. Chain intermediary model analysis showed that initial investment experience influences a novice investor’s behavior through risk perception. In addition, risk perception displayed the characteristics of continuity, in which the initial risk perception would affect later risk perception. These results indicate that investment experience does influence investment behavior. Different early investment experiences have correspondingly significant effects on the novice investors’ investment behavior through their risk perception. The results also suggest that novice investors can partly correct the effects of their initial investment experience through continuous feedback from the stock market.
Quantifying Multifactor Effects on Mud Cake Formation Risk for a Tunnel Boring Machine with the Analytical Hierarchy Process
Authors: Ding Xiaobin , Xie Arnold Yuxuan , Yang Huitai , Li Shijia
Published: January 2023

Tunnel boring machines often encounter clogging during excavation in strata with rich clay content. The clogging can damage the cutterhead and interrupt excavation. Cutting tool clogging, also known as mud cake formation, has a strong effect on excavation work efficiency. While current studies are focusing on the mechanism of clogging, engineering practice still heavily relies on qualitative empirical judgement. To quantitatively assess the risk of mud cake formation, we carefully selected 22 influential parameters to reflect the effect of geological, machinal, and operational risk factors in the tunneling process and established a rubric for risk factor contributions using the analytical hierarchy process (AHP). The results imply the liquidity index, plasticity index, cutterhead torque, and total thrust force contribute to around 45% of the total influence on mud cake formation, while machinal factors are less influential than geological and operational factors. We verified the framework with a tunnel section from the Guangzhou Metro Line 22 that had mud cake formation reported. Rings labelled as high risk for mud cake formation by our framework concurred with those rings with mud cake actually observed. Project log and operational parameter variations were incorporated to explore the connection between mud cake formation and treatment.
Digital Quality Control System—A Tool for Reliable On-Site Inspection and Documentation
Authors: Hussamadin Raafat , Jansson Gustav , Mukkavaara Jani
Published: January 2023

The construction industry has seen an increase in its complexity. This has meant an increased need for time-consuming and costly quality control. Moreover, the construction industry continues to perform detection-based quality controls with little to no focus on prevention. Quality control documentation is a source of information and data that can support the development of construction processes toward prevention. However, current documentations are ambiguous and subjective, so they remain ineffectual. A case study was performed to explore the causes of the ambiguity and subjectivity of traditional quality control documentation, and to analyze the identified project-variable procedure’s transformation into standardized or even automated documentation. Evaluating the traditional quality control’s preparation, inspection, and documentation phases highlighted unique challenges requiring tailored solutions. This study identifies the challenges of inaccurate data creation and data entry, unusable documentation, and inefficient documentation. Therefore, the usefulness of data structuring and process standardization became apparent. Hence, the study explores two solutions: a digitalized quality control system (DQCS) that ensures one accurate structured data entry method, and a centralized unit that prepares the necessary data for quality control inspections, instead of the unique preparation for each project. The results show the benefits of increased accuracy, usability, and efficiency for reliable on-site inspection and documentation.
Combined Annoyance Assessment of Ship Structural Vibration and Ambient Noise
Authors: Liu Hongmin , Lin Xincheng , Gong Zhihao , Shi Jieyuan
Published: January 2023

Background: Noise and vibration are environmental pollutants that endanger people’s productivity and sleep quality in ships, but the coupled effect in ship cabins has not been studied. This study aimed to assess the coupled effect of noise and vibration in ship cabins and propose a comfortable range of noise and vibration. Methods: Three different accommodation cabins were chosen to measure noise and vibration levels and investigate their satisfaction. A revised model combining exponential membership functions was proposed to reveal the relationship between noise and vibration level and its response. The annoyance rate from greater to lesser was classified as A, B, C, D, and E. Results: All measurement levels were satisfied with the acceptance ranges of standards. While subjects felt high annoyance in the crew lounge, subjects in passenger and dining cabins felt slightly annoyed. Conclusions: By combining measurements and subjective investigations, the prediction performance of the revised annoyance model was verified. The noise level reached 57.5 dB(A), and the acoustic condition had a greater impact on subjective feelings than the vibration level. For grade E demands, the vibration level should be lower than 0.095 m/s2, and the noise level should be less than 54 dB(A).
Experimental Application of Robotic Wire-and-Arc Additive Manufacturing Technique for Strengthening the I-Beam Profiles
Authors: Kloft Harald , Schmitz Linus Paul , Müller Christoph , Laghi Vittoria , Babovic Neira , Baghdadi Abtin
Published: January 2023

In recent years, the use of Wire-and-Arc Additive Manufacturing (WAAM) for strengthening standardized steel elements received significant interest within the research community. The reason for this lies in the theoretical potential of WAAM to improve the economic and environmental aspects of contemporary steel construction through efficient material consumption. As efficiency is often obtained through detailed design study, the paper presents a design exploration of suitable stiffener geometries under the assumption of infinite geometrical freedom. The assumption is eventually invalidated as process constraints specific to the generated geometries emerge from test trials. Once identified, process constraints are documented and overcome through adequate and precise path planning. Feasibility analysis is an important step between design and fabrication, especially in the case of large-scale or geometrically complex components. With reference to the case of stiffeners, a feasibility analysis is necessary to take into account the specific geometrical limits of the build volume, which is not typically the case for conventional WAAM fabrication. The current research provides the first investigation to understand the means for future on-site WAAM strengthening of existing steel structural elements.
Out-of-Plane Dynamic Response of Elliptic Curved Steel Beams Based on the Precise Integration Method
Authors: Li Xiaofei , Zhai Haosen , Zhao Dongyan
Published: January 2023

The dynamic response of curved steel beams has long been a research focus in curved bridges. The formula for the dynamic response under a moving load was derived according to the basic principles of the precise integration method. Combined with the necessary conditions of this method, the stiffness matrix of a variable-curvature beam was obtained using matrix inversion, and the mass matrix of the structure was obtained using the concentrated mass method. The dynamic response of the structure was obtained by applying moving loads and masses at different speeds to the curved beam. Finite element simulation and laboratory curved-beam models of the variable-curvature steel beam were established. By comparing the laboratory measurement results against the theoretical data obtained in this study, we propose that our theory has practical engineering significance. It can be used as a theoretical basis for the study of variable curvature steel beam structures and for guiding the construction of curved beams.
The Impact of Internal Courtyard Configuration on Thermal Performance of Long Strip Houses
Authors: Sun Qianqian , Luo Zhixing , Bai Lujian
Published: January 2023

A courtyard is an essential space for natural lighting and natural convective ventilation of residential buildings in hot-humid climates. This study focuses on the internal courtyard configuration on the thermal performance of long strip houses (LSH) in the hot-climate area of Hainan Island, China. The aim is to identify the best design parameters for the courtyard to improve thermal comfort in modern LSH design. Appropriate strategies, including Mahoney table, field investigation, and CFD simulation, are used to determine thermal performance. As a result, the design guidelines of the courtyard are proposed to optimize the thermal comfort towards energy saving. The study reveals the spatial characteristics and climate regulation of internal courtyards in traditional LSH. In addition, the simulation results show that the enclosure with a shaded cover and a high ratio of H/D is conducive to thermal environment and ventilation, and the section of contracted shape from bottom to top is a preferred option in the internal courtyard configuration. This study should, therefore, be of value in designing practical projects with an interior courtyard for architects.
Exploring the Global Research Trends of Supply Chain Management of Construction Projects Based on a Bibliometric Analysis: Current Status and Future Prospects
Authors: Wen Shiping , Tang Handong , Ying Fei , Wu Guangdong
Published: January 2023

With the increasing scale and complexity of construction projects, a considerably growing number of studies have focused on managing supply chain scientifically to improve performance. To explore this field in depth, this paper uses the Bibliometrix R encapsulation tool to conduct a bibliometric analysis and visually display key findings on construction project supply chain management from 1998 to 2021. By using a series of indexes in econometric analysis, this paper introduces an overview of construction project supply chain research. Further, the current situation, historical evolution, and development of this field are explored using the content analysis of keywords. The results suggest that: (1) the number of publications in the field of the supply chain management of construction projects has increased over time and entered a period of rapid growth after 2015. During this period, articles related to ‘sustainability’, ‘prefabricated housing’, ‘reverse logistics’, and ‘lean management’ were widely cited by scholars, but the most frequently cited was ‘partnership’. (2) The keywords in the field of construction project supply chain management can be divided into ‘simulation research’, ‘sustainable research’, ‘method research’, ‘cooperation and integration’, ‘whole life cycle,’ ‘trust and communication’, and so on. The keywords ‘Radio Frequency Identification’ (RFID), ‘waste management’, ‘case study’, and ‘social responsibility’ are the current research hotspots. (3) The theme development of construction project supply chain management can be divided into supply chain integration and management, supply chain process design and optimization, the application of advanced technology, and sustainable supply chain management. This paper summarizes the main discoveries and developments in construction project supply chain management.
Water-Cased Kicker Charges for Use in Explosive Demolition
Authors: Bauer Rachel L. , Pitzel Paul , Johnson Emily M. , Johnson Catherine E.
Published: January 2023

Demolition projects involving explosives often incorporate cutting charges to sever columns in conjunction with kicker charges that “move” the columns out of alignment. Traditional kicker charges use dynamite secured to the column above a linear-shaped cutting charge. This study investigates the use of water-cased kicker charges for use in explosive demolition. The goal is to reduce the fragmentation of steel members and the quantity of explosive needed due to the increased density, incompressibility, and impedance mismatch water provides. Simulations and experimental tests were utilized to determine what type of charges provide the optimal column movement and water placement. Water charges and traditional charges were placed on hanging steel columns that swung freely from a top pivot and analyzed for the fragmentation and velocity of the column. Tests were recorded with high-speed video to calculate velocity and impulse. Simulations showed the same results as experimental tests, with water-cased charges moving the column faster and with more impulse than traditional charges. Experimental testing showed that water-cased charges moved the column 53% faster than traditional in contact charges while simulations showed that water-cased charges moved the column 43% faster than traditional in contact charges. Simulations showed the water tamped behind the charge increased beam velocity 32% while water in front of the charge reduced pressure 38% through dispersion.
Hands-On Quantum Sensing with NV− Centers in Diamonds
Authors: Sánchez Toural J. L. , Marzoa V. , Bernardo-Gavito R. , Pau J. L. , Granados D.
Published: January 2023

The physical properties of diamond crystals, such as color or electrical conductivity, can be controlled via impurities. In particular, when doped with nitrogen, optically active nitrogen-vacancy centers (NV), can be induced. The center is an outstanding quantum spin system that enables, under ambient conditions, optical initialization, readout, and coherent microwave control with applications in sensing and quantum information. Under optical and radio frequency excitation, the Zeeman splitting of the degenerate states allows the quantitative measurement of external magnetic fields with high sensitivity. This study provides a pedagogical introduction to the properties of the NV centers as well as a step-by-step process to develop and test a simple magnetic quantum sensor based on color centers with significant potential for the development of highly compact multisensor systems.