bluuebunny/crossref_metadata_2025 huggingface dataset:
Does continuous wear of a face mask affect your tear film?
Authors: Gunaganti Sony , Koduri Manisai , Mereddy Sravani , Akhter Md Sohail
Published: July 2022

The study's objective was to assess the effect of type of mask wear and duration, including short-term wear of mask on TBUT. This was a cross-sectional, comparative study. A total of 90 subjects were categorized into three groups, each comprising 30 subjects. Either the groups were given a surgical, cloth, or N95 masks to wear. Baseline TBUT was collected after 30 mins without mask wear; subsequently after 1 min of mask wear and after every 30 mins for 3.5 hours among all the three groups. TBUT changes within the groups and between the groups were compared using Friedman ANOVA and the Kruskal Wallis test. TBUT was stable among N95 wearers for first 30 minutes and declined among cloth & surgical mask users. A continuous significant difference was evident only from 2 hours among surgical and cloth mask users and at 3.5 hours within N95 users. N95 wearers have a higher TBUT, and surgical having the least. Surgical mask wears significantly influence tear film stability, followed by cloth mask wear because of air leak from nose wire. TBUT is minimally affected by N95 wear.
survey on prophylactic measures taken by the hyderabadi’s during the 2nd wave of COVID-19
Authors: Priya Shanmuka , Sindhushavishwanatha Sindhushavishwanatha , Kadiri Sunil Kumar , Mallik Arunabha
Published: July 2022

The study's goal is to conducta survey on prophylactic measures taken by the hyderabadi’s during the 2nd wave of covid-19.The current online survey has been conducted by posing 18 questions regarding the extent of prophylactic measures taken by the Hyderabadis during the second wave of the SARS COVID-19 by distributing online Google forms randomly to a large group of the Hyderabadi population which includes 3000 individuals. The Google form contained 18 prominent questions regarding the preventive measures of Covid-19.The results obtained from the survey indicated that 46.3% of individuals were interested to wear an ordinary mask without compulsion, 35.3% of individuals used a surgical mask, 51.5% of individuals followed double masking during the second wave of the COVID-19 and 78.7% majority of individuals had not been tested positive for COVID-19. Few individuals of the population were found to be more prone to consume antibiotics (28.7%), especially Azithromycin and corticosteroids (8.1%) such as betamethasone and dexamethasone as a prophylactic measure for the corona infection.
Analysis of patient health condition based on hybrid machine learning algorithm
Authors: Kumar Anil N. , Vanaja D. S. , Reddy Alumuru Mahesh , Das Susmita , Dey Sharmistha , Sucharitha Yadala
Published: July 2022

In data mining, the classification methods are used to determine the relationships between the various objects of the interactions database. In this research, the objective is predominantly focused on the prediction of three types of functioning test level. The main purpose of the research work is to analyze human health condition, realised by fluctuation of specific ranges such as Bilirubin, Albumin, Prothrombin time (INR), Ascites, Encephalopathy , Bicarbonate, Calcium etc. It can improve the disease by taking medical diagnosis based on Apriori algorithm by generating rule for the most significant parameters of all three functioning test level. In this article, the experiment can be carried out by using a variety of different sizes of support count based on the association factor of attributes in the kidney and liver functional test data from a wide range of patients. The goal of the experiment is to gain an understanding of the effect that the Apriori algorithm has on the amount of time it takes for the execution, the precision of the best rule discovered from the mining of frequent patterns, and the number of association rules that are generated.
Internet of medical things
Authors: Kawale Sheetalrani R. , Narmadha D. , Nancy R. Golden , Mule Shumye Birhan , Verma Basant Kumar , Reddy Pundru Chandra Shaker
Published: July 2022

Internet of Medical Things (IOMT) is playing critical role in healthcare business to boost the accuracy, reliability and efficiency of electronic equipment. Researchers are working towards a computerized healthcare system by integrating the existing medical resources and healthcare services. As IOT converging different sectors but our emphasis is connected to research contribution of IOT in healthcare domain. This study covers the peoples contribution of IOT in healthcare sector, application and future problems of IOT in term of medical services in healthcare. We do expect that our study will be valuable for academics and practitioners in the area, allowing them to comprehend the tremendous potential of IoT in medical domain and identification of important problems in IOMT. This investigation would also allow the academics to comprehend applications of IOT in healthcare area. This input would allow the academics to comprehend the prior contribution of IOT in healthcare business.
AI based contactless attendance monitoring and management system
Authors: Nithya J. , Vignesh S. R. , Devadarsan A. , Venkatesh S.
Published: July 2022

The traditional methods of attendance marking need to be replaced with an Artificial Intelligence based attendance monitoring system. The process of checking attendance using the existing methods is time consuming and open to easy fraud. The usage of Bio-metrics poses the threat of viruses. A contact-less Attendance Management System (CAMS) is proposed to overcome the above challenges. AI based attendance monitoring system will record the students attendance automatically while they enter the class, by recognizing their faces. The in-time and out-time of the students are also recorded on a regular basis. The Holistic Face Matching algorithm is used to compare the facial images. The total time duration, the students were present inside the class can be easily calculated. There is no chance of fake attendance as each student has to record his or her facial identity. The main objective is to achieve reliability, accessibility and security in a very efficient way. The results showed that by interfacing a face recognition system with a server, a real-time attendance system can be built and be monitored automatically. Finally, the student’s attendance details can be updated in the academic management system.
Online E-voting system by using blockchain technology
Authors: Dhivya V. P. , Thangalakshmi J. , Sri Anitha R. , Pavatharani S.
Published: July 2022

Fundamental legitimate to cast a ballot or really balloting in decisions administration the reason of a majority rules government the way of behaving of intermittent forceful participatory believable and peaceful races is one of the significant measuring sticks used to conclude the popularity based circumstance of a country in Nigeria decisions had been done the utilization of the aide device of balloting ever because we started rehearsing a majority rule government in 1999 anyway those decisions the utilization of the aide approach had been damaged with heaps of electing acts of neglect and hitches of fierce attack at the electorate final product controls vote looking for distance of surveying offices, etc. those are adequate thought processes that requires the design and formation of an advanced balloting contraption that is going a lengthy way in tending to limit of those inconveniences the e-balloting device focuses to get rid of the bottlenecks prominent with inside the aide balloting device alongside the delayed enlistment system pointless transportation political race viciousness and over the long haul the amazingness of the votes this become finished through growing a period strong enrollment stage which enrolls a citizen and doles out a citizen their electorate card.
Production potential of transplanted rice as influenced by pre and post emergence herbicides
Authors: Prasath V. Rajendra , Ramesh S. , Sundari A. , Sriramachandrasekharan M. V.
Published: July 2022

A study was designed on the way to evaluate and identify the pre and post emergence herbicide combinations in transplanted rice variety ‘ASD 16’ during February-May 2020 at the Experimental Farm, Department of Agronomy, Annamalai University, Tamil Nadu, India. The experiment was laid out in randomized block design with three replications and fourteen treatments. The treatment details includes sequential application of pre and post emergence herbicide viz., pre-emergence herbicides (butachlor, pretilachor and pyrazosulfuron ethyl) and post emergence herbicides (bispyribac sodium, metsulfuron methyl + chlorimuron ethyl, fenoxaprop-p-ethyl and triafamone + ethoxysulfuron), hand weeding twice (20 and 40 DAT) and unweeded control plot. All the weed management practices were found to be significantly influenced the weed biometrics, growth attributes, grain and straw yields of transplanted rice. The result of the study clearly showed that hand weeding twice at 20 and 40 days after transplanting (DAT) significantly registered lesser weed dry matter production, weed index, maximum weed control index (WCI), higher growth attributes viz., plant height, number of tillers hill-1, DMP, grain and straw yields.
In silico ADMET screening & molecular docking of some 1-(5-(4-chlorophenyl)-1,3,4-oxadiazol-3(2H)-yl) ethanone derivatives to be developed as triple mutant T790M/C797S EGFR inhibitors
Authors: Magar Sagar D. , Pawar Pratap Y.
Published: July 2022

EGFRs' high expression and/or adaptive activation coincides with the pathogenesis and development of many tumors, making them appealing candidates for both diagnosis and therapy. Several strategies for targeting these receptors and/or the EGFR-mediated effects in cancer cells have been established. A lot of in silico models are developed for prediction of chemical ADMET properties. However, it is still not easy to evaluate the drug-likeness of compounds in terms of so many ADMET properties. In present study, we have designed some 1-(5-(4-chlorophenyl)-1, 3, 4-oxadiazol-3(2H)-yl) ethanone derivatives to be developed as potential EGFR inhibitors for the treatment of cancer. The designed derivatives were screened through Lipinski rule, Veber’s rule, ADMET analysis, drug-likeness properties and molecular docking.  We concluded that all the compounds sm1, sm2, sm3, sm8, sm9, sm10, sm11, sm12, sm13, sm14, sm15, sm18, and sm19 were found to possess drug-likeness properties and therefore were subjected for molecular docking studies. From molecular docking studies it was observed that Molecules Sm3, Sm8, Sm9, Sm10, Sm12, and Sm2 had formed either three or two conventional hydrogen bonds with EGFR enzyme and hence selected for synthesis which can be developed further to get more promising molecules for the treatment of cancer.
Influence of monopoly game "MonAS" in increasing Posyandu Cadre's knowledge of stunting
Authors: Sari Dewi Indah , Wahyuni Ninik
Published: July 2022

Stunting is a chronic nutritional problem caused by multifactor, one of which is the lack of maternal knowledge about exclusive breast milk. Kader Posyandu who is the chosen person in the community becomes an extension of the health workers in providing health information so that the knowledge needed is needed in order to be able to convey the information obtained. The aim of the study was to increase cadre knowledge regarding stunting prevention with Exclusive breast milk through monopoly games.  This type of research pre-experimental design one group pretest – posttest. The sample used in this study is the population of Posyandu cadres of Tambakbaya village of Cibadak Kab.Lebak District which is as many as 45 people. Intervention in this research is a monopoly game that has been modified which is in accordance with the purpose of the research.  The results obtained that the monopoly game MonAS has a significant influence on the increase in the knowledge of posyandu cadres regarding stunting. With the results of this study is expected to be a new method in dreaming health information to cadres, namely through games.
use of English neologisms in social media
Authors: Sabir Paiman Hama Salih
Published: July 2022

This study examines a linguistic phenomenon, which is using English neologisms by Iraqi Kurdish Facebook users on their Facebook platforms. Nowadays, hundreds of newly established English lexical units such as blogger, tweet, Facebook, WhatsApp, share, etc.… flow into English lexicon daily due to the innovative technology, internet websites, and all sorts of social media; hence, some of these new words find their way into world language’s vocabulary through the netzines communications. The paper aims to (1) explore the extent of using English neologisms by Iraqi Kurd Facebook users on Facebook, (2) determine the morphological classes of these words (3) reveal the most prominent reasons and factors behind using such English neologisms, and (4) pinpoint their significance in Kurdish lexicon. To achieve the aims of the study, data are obtained in two ways; first, compiling a list of 500 English neologisms through a thorough observation from numerous Kurdish public page posts and updates and comments of a reliable number of personal FB accounts of Iraqi Kurd FB users. Second, ask 56 active FB users, who are all BA, MA and PhD holders with good English background to tick the English neologisms from the list above.
Study the effect fe doped tin oxide for gas sensing applications
Authors: Mahmoud Arshad Ahmed , Mohammad J. F.
Published: July 2022

Nanocrystalline transparent conductive tin dioxide (SnO2) and Fe doped SnO2 films were prepared by the chemical spray pyrolysis technique (CSPT). X-ray diffraction (XRD) pattern shows that the SnO2 ﬁlms are polycrystalline of tetragonal structure with the preferential orientation of (110) direction and intensity decreases with increasing Fe doping. The results of the film morphology study by SEM show that the films contain nanoparticles with different size distributed on the film. The study of the optical properties reveals that SnO2 films have high transmittance in the visible region and decrease with Fe doping. The optical energy gaps of the SnO2 thin ﬁlms decrease slightly from 3.87 eV to 3.63 eV due to the increase in Fe doping.
Study of immune response of immune mediator interleukin (17 and 23) against dermatophytes infection
Authors: Nawfal Basim Namah , Zghair Fadhil Sami
Published: July 2022

Dermatophytosis (superficial fungal infections) is a type of fungal infection that arises mostly on dead keratin found in the top layer of the skin, hair, and nail. Dermatophytes are classified into three genera: Trichophyton (which causes diseases on the skin, hair, and nails), Epidermophyton (which causes infections on the skin, hair, and nails), and Microsporum (which causes infections on the skin, hair, and nails) (causing infections on skin and hair). Molecular methods for the differentiation between the genotyping characteristics of the species of dermatophytes are more specific, precise, and rapid than traditional methods, and they can discriminate between closely related species while being less susceptible to interference from external factors such as temperature variations and chemotherapy, among others. Trichophyton rubrum is the most common fungi that causes dermatophytosis, Molecular diagnosis is the best and most accurate method for diagnosing fungi, There is a clear variation in the genetic structure of local and global fungal isolates. High rate of interleukins (IL17, IL23) with fungal infections Culture on Sabouraud's Dextrose Agar ( SDA ) , required for species identification, was positive in 30 ( 28.3 % ) and negative in 76 (71.7 % ) of cases.
Avifauna associated with two fragments of tropical dry forest located near airports in La Guajira – Colombia
Authors: Leyn Castro-Vásquez  , Yamileth Dominguez-Haydar  , Edisson Castro-Escobar
Published: July 2022

Introduction: In Colombian territory, some aerodromes are close to natural areas, of which there is no information on their biodiversity. This research recorded the avifauna of two Tropical Dry Forests (TDF) near airports, becoming the first work of its kind in Colombia. Objective: to establish an approximation of the avifauna and the conservation status present in TDF fragments near the airports in La Guajira - Colombia. Materials and methods: linear transects were carried out in the TDF close to the Jorge Isaacs and Almirante Padilla airports, in addition, their avifauna was compared with that reported in two TDF of La Guajira, these were: Rancherias Itaka and Alto Pine (secondary source of information). The degree of similarity between the four TDF was determined by Jaccard's coefficient. Results: In the TDF of the Jorge Isaacs airport, a total of 45 species were reported and for the Almirante Padilla airport, 34 species. Little affinity was obtained between the birds of the TDF de las Rancherias and the Almirante Padilla with the Jorge Isaacs, which could be related to the presence of human settlements near these forests, observing Hemisynanthropic birds. In the Jorge Isaacs, the environmental pressure was limited to that exerted by aeronautical activities, therefore, Anisanthropic species were recorded, which would indicate the maintenance of the vegetation cover. Conclusion: The TDF near airports in La Guajira represent important sites for bird conservation, for this reason, it is necessary to continue studying them and seek strategies that guarantee their conservation.
Waist circumference and waist-to-hip ratio as indicators of abdominal obesity
Authors: Neha Singh  , Nupur Hooja  , Angela Yadav  , Premlata Mital  , Aditi Jaiswal  , Pooja Bairwa
Published: July 2022

Obesity is linked to various gynaecological conditions like polycystic ovary syndrome (PCOS) and leads to metabolic syndrome. Early diagnosis of visceral obesity would help control the occurrence and progression of these diseases The aim of the study was to compare waist circumference and waist-to-hip ratio with body mass index (BMI) as indicators of abdominal obesity. This cross-sectional study was conducted on 44 women with Polycystic ovary syndrome (PCOS) fulfilling Rotterdam criteria over a period of one year. Height, weight, waist circumference and hip circumference were measured. BMI and waist to hip ratio were calculated. These were compared with each other. Overall, average waist circumference and waist to hip ratio were found to be 68. 69 cm and 0. 82 respectively and mean BMI was 23. 07 kg/m2. The prevalence of obesity by BMI was 69%, abdominal obesity for WC was 59. 1% while for WHR 61. 36 %. Waist circumference was found to have high positive correlation with BMI (r=0. 75) compared to waist to hip ratio (r=0. 40). Thus, waist circumference and waist hip ratio are easy methods of measuring fat distribution and can be used for the monitoring the development of metabolic syndrome in PCOS.
Transformação Comunicacional na Aprendizagem da Língua Portuguesa: um Estudo na Universidade Nacional Timor Lorosa’e.
Authors: M. Faria Paulo , Soares Susana
Published: July 2022

O contexto coloca sempre renovados desafios a professores e alunos. Também o processo de ensinar e aprender está cada vez mais associado à utilização de recursos digitais, que se traduz numa abordagem multiliterácita e multimodal no ensino da língua. No contexto de ensino superior da Universidade Nacional Timor Lorosa’e, o smartphone é um recurso que se privilegia em diversas tarefas desenvolvidas nas sequências didáticas de uma unidade curricular de 1.º ano do ensino de língua portuguesa. Quanto à metodologia, optou-se por realizar um estudo que incide numa abordagem de natureza qualitativa, embora se apresentem resultados estatísticos decorrentes dos dados recolhidos por questionário e por diário de bordo. Os instrumentos de recolha de dados possibilitaram identificar i) as características biográficas e socioeconómicas do grupo; ii) o acesso a meios digitais e o uso que deles é feito; iii) as atividades para as quais se recorreu ao telemóvel em contexto de sala de aula e iv) a perceção sobre essas atividades em termos de vantagens e desvantagens. Deste artigo, que constitui a primeira fase de um estudo mais amplo, pode concluir-se que, apesar de a utilização de meios digitais colocar exigências suplementares à docência, esse é um caminho sem retorno. Por conseguinte, a necessidade de desenvolver nos alunos novas competências de análise discursiva, a ponto de os capacitar para representar o mundo a partir de diferentes modos semióticos, deve constituir um ponto central na organização e dinamização das atividades pedagógicas.
Linguagem como um Sistema Formal e Rede de Práticas da Comunicação.
Authors: Paulino Vicente
Published: July 2022

Neste artigo pretende-se falar da linguagem como um sistema formal e uma rede de práticas da comunicação e da produção de sentidos. Procurando definir o que é a comunicação e a linguagem, do mesmo modo, a forma como se produz o sentido do dizer de um algo, ou querer dizer (significar) um algo. Pretende-se explicar a produtividade e a sistematicidade da linguagem e os usos convencionais de muitas elocuções na produção de sentido do ato da fala, incluindo ‘dizer é fazer’ numa compreensão da linguagem enunciativa e jogos da linguagem na comunicação.
On the Enigma of the Portuguese Diamond.
Authors: Pinto Casquilho José
Published: July 2022

The Portuguese Diamond is the largest faceted diamond in the National Gem Collection of the National Museum of Natural History, Washington DC; with an emerald cut at 127.01 carats is almost a perfect octagonal gem. Its name was given by the last private owner, Harry Winston, on the basis that once it had belonged to the Portuguese crown jewels. Yet, the mystery follows in that several authors say, with greater emphasis nowadays, that the name “The Portuguese Diamond” came from a mistaken legend. The first goal of this paper is to show that there is strong iconic evidence that the diamond belonged to King José I of Portugal in the eighteenth century and, presumably, with a lesser degree of certainty, to other following sovereigns of the house of Bragança (Braganza). Subsidiary goals are the disambiguation with some other Brazilian precious stones mentioned in news or other sources. One will also look for establishing a plausible documented origin of the Portuguese Diamond, then giving some possible clues on the fate and oblivion of the diamond for about a century, until its resurgence in the USA. Last, it is sketched a framework of its semiotic convolution as an object of desire and an index of power, from the Portuguese royalty into the veil of secrecy, and then to the American capitalist democracy.
An Integrated QFD Models with Variety Management
Authors: Zhang Jingzhi
Published: July 2022

Improving Design for Variety (DFV) can satisfy more customer requirements, but increase the complexity of product design and manufacturing. QFD, also known as House of Quality (HOQ), is a method that transforms Customer Requirements (CRs) into Engineering Characteristics (ECs), and then transforms ECs into Components Design (CDs). DFV include the variety in products and in components, and the product variety needs to be realized in component variety. With QFD, it is possible to transfer the requirement of CR to the requirement of CD including variety requirement. How QFD responds to DFV management so that it can plan ECs considering the impact of design changes on CDs was examined. This paper proposed a QFD optimization model that can quantify the interrelationships among ECs and support DFV management. A case study on an automobile development verified the effectiveness and feasibility of the proposed model.
Tencent’s Business Model and Business Strategy
Authors: Shang Yufei
Published: July 2022

In the competitive practice, a set of practical and unique corporate business models is the key to superiority in the market competition. Nevertheless, since the different perspectives of the researchers, resulting in the lack of unified understanding of the basic concept, structural system, and theoretical scope of business models, the research on enterprise business models has not formed a unified theoretical framework yet. Based on that, to better guide Chinese enterprises in successful enterprise business models, this paper explores the strategies for the design and innovation of enterprise business models, and attempts to provide ideas for the change of existing business models. Through the basic science research of Tencent's official, it could be found that the official operation model is roughly divided into three parts: Internet technology value-added services, mobile communication value-added services, and Internet advertising. The sales market began to be occupied by the official QQ of Tencent, and a large number of visitors were attracted, resulting in a fixed customer base. By maintaining a high number of hits and popularity, further development of other regions was carried out to gain profits. Tencent officials know their customer base well enough to provide them with a satisfactory service, no matter where the customer is. Most of Tencent's official business processes are aimed at the younger demographic. Taking advantage of customers' blind comparisons, curiosity, and other psychology, they deduct specific fees from various Unicom value-added services to gain profits.
In search of pedagogical approaches to teaching business ethics in the era of digital transformation
Authors: Swartz Ethne , Brennan-Tonetta Margaret , Jain Rashmi , Johnson Marina , Mamanov Stanislav , Hale Matthew , Jayaraman J.D.
Published: July 2022

The authors explore the challenges in teaching business ethics in an era of digital transformation, provide an understanding of the limitations of traditional ethics approaches, and explore emerging approaches that may more effectively deal with the ethical complexities of the new digital era. Building on prior research conducted during December 2018 and January 2019 regarding the skills required for jobs in the big data field, the authors argue that business ethics must be an essential skill for those working in this field.  Ethical frameworks in big data and information management are explored including Universalist, Integrative Social Contract Theory and Care Theory, as well as agency, disciplinary, contextual and outcomes considerations. The authors posit that traditional ethical frameworks such as Universalist approaches, are no longer sufficient to guide decision making in an era of digital transformation and the “datafication” of society. Therefore, business educators have a duty to cultivate critical thinking mindsets in their students and the adoption of “responsible innovation” principles, similar to those developed in the science and technology innovation literature.
Four-Class Emotion Classification Problem using Deep Learning Classifiers
Authors: Zhou Miaojie , Tripathi Abhishek , Srinivasan Satish Mahadevan
Published: July 2022

Social media sites and blogs generate a vast amount of emotionally rich data in the form of tweets, status updates, blog posts etc. Such textual data are a good representative of emotions expressed by an individual or a group of people on any given topic. By analyzing the emotions within these textual data, we can get an idea about how an individual or a community expresses their views. Analytical techniques are widely used for analyzing emotions within these texts. However, due to the imbalanced nature of the training datasets the supervised classifiers fail to clearly classify the different emotion classes. As a result, these classifiers demonstrate a poor performance in identifying emotions within the texts. Here, using a constructed heterogeneous training dataset from well-known training datasets we have trained two deep learning models namely the Convolutional Neural Network (CNN), and Recurrent Neural Network (RNN) to address a four-class emotion (Anger, Sadness, Happy, Surprise) classification problem. By appropriately tuning the hyper parameters of the deep learning classifiers our study reveals that the CNN classifier has a slightly better performance (77%) than the RNN classifier (76%) for a four-class emotion classification problem.
Textual Data Distributions: Kullback Leibler Textual Distributions Contrasts on GPT-2 Generated Texts, with Supervised, Unsupervised Learning on Vaccine & Market Topics & Sentiment
Authors: Samuel Jim , Palle Ratnakar , Soares Eduardo Correa
Published: July 2022

Efficient textual data distributions (TDD) alignment and generation are open research problems in textual analytics and NLP. It is presently difficult to parsimoniously and methodologically confirm that two or more natural language datasets belong to similar distributions, and to identify the extent to which textual data possess alignment. This study focuses on addressing a segment of the broader problem described above by applying multiple supervised and unsupervised machine learning (ML) methods to explore the behavior of TDD by (i) topical alignment, and (ii) by sentiment alignment. Furthermore, we use multiple text generation methods including fine-tuned GPT-2, to generate text by topic and by sentiment. Finally we develop a unique process driven variation of Kullback-Leibler divergence (KLD) application to TDD, named KL Textual Distributions Contrasts (KL-TDC) to identify the alignment of machine generated textual corpora with naturally occurring textual corpora. This study thus identifies a unique approach for generating and validating TDD by topic and sentiment, which can be used to help address sparse data problems and other research, practice and classroom situations in need of artificially generated topic or sentiment aligned textual data.
An overview of the general characteristics, pathogenicity, transmission, and diagnosis of human papilloma virus (HPV)
Authors:   Department of Microbiology, Faculty of Natural Sciences, Ibrahim Badamasi Babangida University, Lapai, Nigeria, MAGAJI YAHAYA GARBA , KOLO IBRAHIM ,   Department of Microbiology, Faculty of Natural Sciences, Ibrahim Badamasi Babangida University, Lapai, Nigeria, BABA JOHN ,   Department of Microbiology, Faculty of Natural Sciences, Ibrahim Badamasi Babangida University, Lapai, Nigeria, SULEIMAN KAFILAT OLAYEMI ,   Nile University, Abuja
Published: July 2022

Mucous membrane infections are brought on by the double-standard DNA virus known as human papillomavirus (HPV). Cervix cell alterations are caused by a sexually transmitted illness. E6 and E7 oncogenes play a critical role in HPV infection. Finding these genes to identify HPV strains, particularly the HPV16 strain, will have a significant impact due to its exceptional sensitivity, the dielectric electrochemical biosensor stands out among other pathogen detection methods. Recent evidence suggests that E6 and E7 are also important in inhibiting the innate immune response of the host cell to HPV. Viral replication is mediated by the E1 and E2 proteins in conjunction with other biological stimuli. E2 has also been linked to viral and cellular transcriptional regulation. Despite decades of research, the function of other viral proteins still remains unclear. Therefore, analysis of Human Papilloma Virus (HPV) characteristics, pathogenicity, transmission and diagnosis were reviewed. We concluded that we now have the tools and methodologies necessary to answer this critical question about viral tropism. The discovery of efficient treatments to cure or prevent HPV-induced illness is just as vital as studying the underlying mechanisms of HPV pathogenesis. The identification of drugs specifically to treat HPV infection has not been highly successful due to the complexities of the HPV life cycle and the limited number of enzymatic activities identified for HPV proteins. The development of drug treatments for existing HPV disease is an important undertaking that deserves further attention. In this regard, the development of therapeutic vaccines and self-protection are promising area of investigation and needs to be further supported.
Plant species diversity along an altitudinal gradient in Simbalwara wildlife sanctuary, Himachal Pradesh
Authors: Verma R. , Subramani S. , Kapoor K. , Kumar Surinder
Published: July 2022

The composition of forest vegetation along an altitudinal gradient (400 to 650m) in Simbalwara Wildlife Sanctuary was studied during August, 2003. The forest is composed of 53 species of trees, 32 of shrubs and 175 of herbs. The plant communities identified at 400-525m and 525-650m elevation range were Shorea robusta – Mallotus philippensis and Shorea robusta – Terminalia alata respectively. On the basis of importance value index (IVI), Shorea robusta was the dominant tree species at both the elevation ranges. The distribution pattern of plant species was random and contiguous at both the altitudes. The concentration of dominance was lower and index of diversity higher for plant species at both the altitudes Index of diversity for trees was 4.390 and 3.942 at 400-525m and 525-650m elevation range respectively. The index of similarity for trees, shrubs and herbs between two altitudes was 0.64, 0.65 and 0.54 indicating remarkable degree of similarity in plant species. The population structure of tree species is represented mainly by two patterns, one represented by greater proportion of individuals in seedlings stage indicating frequent reproduction and another indicating more individuals in intermediate girth classes with absence of seedlings. If the latter trend continues for longer period, the species may disappear from the area in near future.
C40: Plasmocytome solitaire rachidien : Prise en charge au service de neurochirurgie de l’hôpital Général Idrissa Pouye (HOGIP)
Authors: Faye M , Gaye M , Dial M C , Doumbia N , Fondo I A , Sakho Y
Published: July 2022

INTRODUCTION : Le plasmocytome solitaire rachidien est une tumeur maligne représentant environ deux à 5% de l'ensemble des proliférations plasmocytaires. MATERIELS ET METHODES : Il s'agit d'une étude rétrospective portant sur sept patients pris en charge dans le service de Neurochirurgie de l’Hôpital Général Idrissa Pouye pour un plasmocytome solitaire rachidien avec preuve histologique de prolifération plasmocytaire et une lésion unique du corps vertébral à l’imagerie. RESULTATS : Cinq hommes et deux femmes ont été colligés. L’âge moyen était de 51,3 ans (23 – 75). La topographie des lésions était dorsale dans trois cas, lombaire dans trois cas et cervicale dans un cas. Six des sept patients ont été opérés dans le service et le prélèvement envoyé au service d’Anatomopathologie de HOGIP (laminectomie associée à une ostéosynthèse par voie postérieure dans trois cas, un abord antérieur chez un patient et une laminectomie simple dans deux cas). Un patient a bénéficié d’une biopsie vertébrale scanno-guidée. Tous les patients ont été secondairement envoyés au service d’Hématologie Clinique de l’Hôpital Dalal Diam où un traitement complémentaire a été mis en route en collaboration avec le service de Radiothérapie. Avec un suivi moyen de 11,6 mois (huit à 36), une récidive locale a été notée chez deux patients à six et neuf mois. Une évolution vers un myélome multiple a été noté après un an de traitement chez un patient. Quatre de nos patients sont actuellement en rémission. Un décès a été noté. CONCLUSION : La radiothérapie associée à la chirurgie d’exérèse constitue un traitement efficace du plasmocytome solitaire vertébral. Son pronostic est affecté par l'évolution vers le myélome multiple, ce qui justifie une surveillance rigoureuse après traitement.
C41: Cancers du côlon gauche en occlusion au service des urgences du Centre Hospitalier Régional de Thiès (Sénégal)
Authors: Ba P A , Diop B , Ken K C , Diouf A
Published: July 2022

INTRODUCTION : L’occlusion intestinale représente une complication évolutive des cancers du côlon gauche. Elle représente un facteur de mauvais pronostic indépendant pour cette pathologie. L’objectif de notre travail était d’étudier les différentes options thérapeutiques chirurgicales et les résultats. MATERIELS ET METHODES : Il s’agit d’une étude rétrospective descriptive menée sur une période de huit ans (Mars 2012 à Décembre 2020). Etaient inclus tous les patients opérés au niveau du service des Urgences du Centre Hospitalier Régional de Thiès pour une occlusion intestinale aiguë secondaire à un cancer du côlon gauche avec confirmation anatomopathologique de la pathologie tumorale. RESULTATS : Vingt-sept patients répondaient à nos critères d’inclusion. La moyenne d’âge des patients était de 51,18 ans (27– 85 ans). Nous avions noté une prédominance féminine avec un sex-ratio de 0,50. Le taux de résécabilité était de 85,19%. Quinze patients (65,22%) avaient eu une colectomie segmentaire et huit une hémi-colectomie gauche (34,78%). La chirurgie en un temps était pratiquée chez 12 patients (44,44%). L’intervention en deux temps était effectuée dans 40,74% des cas, dont deux cas de colostomie première et neuf cas de résection suivie d’une stomie. Sept patients avaient bénéficié secondairement d’un rétablissement de la continuité digestive. Chez quatre patients (14,81%) une chirurgie palliative était effectuée (une dérivation iléo-rectale, une dérivation iléo-colique gauche et deux stomies latérales définitives). Dix patients (37,04%) présentaient des complications précoces à type de troubles ioniques et de suppuration pariétale. Un patient (3,70%) était décédé des suites d’une défaillance cardiovasculaire. Sur le plan histologique, toutes les tumeurs étaient des adénocarcinomes majoritairement Lieberkuhniens. Vingt-cinq patients (92,5%) avaient été orientés pour une chimiothérapie. La mortalité globale dans notre série était de 33,33%. CONCLUSION : La prise en charge des cancers du côlon gauche en occlusion implique la levée de l’occlusion en urgence mais aussi le traitement de la pathologie tumorale. Le traitement doit aussi s’inscrire dans une stratégie pluridisciplinaire, en prenant en compte l’état du patient et l’expérience du chirurgien.
C42: Taux de survie des cancers colorectaux en Afrique : Revue systématique et méta-analyse
Authors: Diallo A C , Ndong A , Thiam J I A T , Ba M B , Dieng P S , Somé R O , Diouf D , Dieng M M , Ka S , Dem A
Published: July 2022

INTRODUCTION : Le cancer colorectal est le troisième cancer le plus fréquent au monde et la quatrième cause de mortalité. L’incidence augmente régulièrement d’année en année dans les pays occidentaux et on note une augmentation des cas en Afrique. Malgré cette incidence et cette mortalité non négligeable, il existe peu de données factuelles sur ce cancer. L’objectif de cette étude était d’avoir une vue globale de la prise en charge des cancers colorectaux et de mesurer la survie globale des cancers colorectaux en Afrique. MATERIELS ET METHODES : Une recherche systématique de la littérature a été réalisée concernant les études sur les cancers colorectaux en Afrique. Les données concernant le nom de l’auteur, l’année de publication, la période de l’étude, la taille de l’échantillon, le pays de l’étude et la survie à un an, trois ans et cinq ans ont été recueillies. Les études prenant en compte d’autres localisations cancéreuses ont été exclues. La qualité des études a été évaluée par l’échelle de Newcastle-Ottowa pour les études de cohorte. L’hétérogénéité des études a été évaluée avec le Cochran Test (avec une significativité de moins de 0,1) et le I2 test (p-value de 0,5). Si les données sont hétérogènes, un random effect-model sera utilisé pour interpréter les résultats de la méta-analyse basée sur les survies à un an, trois ans et cinq ans. Dans le cas contraire, l’interprétation se basera sur un fixed-effect model. Toutes les analyses ont été faites grâce au logiciel MedCalc© version 14.8.1. RESULTATS : Vingt-trois études ont été incluses dans notre revue systématique. La plus ancienne était en 2003 et la plus récente en 2021. L’âge moyen de survenue des cancers colorectaux était de 49,93 ± 8,58 ans (31,25 – 64,1 ans).  La survie à un an était de 61,74% [IC 95% (46,27-76,07)]. La survie à trois ans était de 26,24% [IC95% (18,01-35,42)]. La survie à cinq ans était de 19.56% [IC95% (7,51-35,54)]. CONCLUSION : Le cancer colorectal est l'une des tumeurs malignes de meilleur pronostic. S’il est diagnostiqué à un stade précoce, les taux de survie des patients augmentent considérablement. Les résultats de cette étude indiquent que ces taux de survie, en particulier à cinq ans, sont inférieurs à ceux des autres régions du monde. Une amélioration des programmes de dépistage, du traitement des cancers colorectaux pourrait augmenter la survie globale.
C45: Syndrome de Wilkie : A propos de 6 observations
Authors: Gueye M L , Seye Y , Sarr I S S , Faye P M , Ndiaye M , Thiam O , Touré A O , Seck M , Cissé M , Ka O , Dieng M
Published: July 2022

INTRODUCTION : Le syndrome de la pince aorto-mésentérique ou syndrome de Wilkie est une entité rare. Il est défini par la compression de la troisième portion duodénale au niveau de l’angle formé par l'artère mésentérique supérieure et l'aorte abdominale. La tomodensitométrie permet de poser le diagnostic. Les étiologies sont variées et le traitement peut être conservateur ou chirurgical. Sa prise en charge ne doit souffrir d’aucun délai sous peine de grever le pronostic. Nous rapportons 6 cas de syndrome de Wilkie, d’étiologies et de pronostics divers. OBSERVATIONS : Il s’agissait de six patients, dont trois de sexe masculin ; l’âge moyen était de 34,2 ans. Le motif de consultation était un syndrome de sténose digestive haute (six). Les circonstances de survenue étaient une chirurgie d’arthrodèse du rachis pour une scoliose idiopathique à J3 post-opératoire (un) ; un amaigrissement récent important faisant suite à une gastroentérite sévère sur terrain diabétique (un) ; une toux vespéro-nocturne avec syndrome infectieux (deux) et un terrain d’anxiété avec anorexie (un) et une tumeur antro-pylorique (un cas). La TDM abdominale montrait dans tous les cas (six) : un angle aorto-mésentérique inférieur à 22 degrés. La distance aorto-mésentérique était également inférieure à huit mm dans les six cas. Trois patients avaient un taux de protidémie bas. Un traitement conservateur était instauré chez trois patients, avec la mise sous nutrition parentérale exclusive chez ces patients. L’évolution était marquée chez ces trois patients par une régression des symptômes (un), un décès (un) par probable syndrome de Mendelson, et une irritation péritonéale au 3ème jour de la nutrition parentérale, imposant une exploration chirurgicale (un). Celle-ci montrait une nécrose gastrique étendue sur un estomac hyper dilaté et une compression du D3. Chez les trois autres patients, l’indication chirurgicale était retenue d’emblée. Les gestes réalisés (trois) étaient : une duodéno-jéjunostomie trans-mésocolique sur D3 (un), une gastro-entéro-anastomose trans-mésocolique (un) et une gastrectomie totale avec anastomose œso-jéjunale (un). CONCLUSION : Le syndrome de Wilkie est une affection rare, qui se manifeste par un syndrome de sténose digestive haute. Un amaigrissement récent ou une chirurgie du rachis sont des terrains à rechercher systématiquement devant cette symptomatologie. Le traitement repose sur une nutrition parentérale, qui en cas d’échec, impose une chirurgie dans les meilleurs délais.
On the Hausdorff dimension distortions of quasi-symmetric homeomorphisms
Authors: Huo Shengjin
Published: July 2022

In this paper, we first prove that for a Fuchsian group \(G\) of divergence type and non-lattice, if \(h\) is a quasi-symmetric homeomorphism of the real axis \(\mathbb{R}\) corresponding to a quasi-conformal compact deformation of \(G\), then \(h\) is not strongly singular for divergence groups. This generalizes a result of Bishop and Steger (1993). Furthermore, we show that Bishop and Steger's result does not hold for the covering groups of all \(d\)-dimensional 'Jungle Gyms' (\(d\) is any positive integer) which generalizes Gönye's results (2007) where the author discussed the case of 1-dimensional 'Jungle Gym'.
Влияние установки на восприятие «Я»- и «не-Я»-феноменов на уровни их конструирования
Authors: Медведев Богдан
Published: July 2022

Представлен краткий обзор активно развивающейся и набирающей популярность среди зарубежных исследователей теории конструктов разного уровня (Construal Level Theory). Утверждается фундаментальная взаимосвязь между психологической дистанцией до феномена и уровнем (абстрактностью) его конструирования (репрезентации) в сознании субъекта. Описываются предпосылки и возможная научная значимость выделения двух специфичных видов конструирования: «Я»- и «не-Я»-феноменов. Предполагается, что уровни их конструирования в некоторых ситуациях могут изменяться независимо друг от друга. С целью изучения данного вопроса было проведено экспериментальное исследование, в котором приняли участие 130 человек. Испытуемым предлагалось поочередно выполнить три задания: пре-теста, основного задания и пост-теста. С помощью основного задания (называния в течение 5 минут только «Я»- или «не-Я»-феноменов, или же отсутствие ограничения для контрольных групп) формировалась установка на восприятие «Я»- или «не-Я»-феноменов. Во время пре- и пост-тестов испытуемым предлагалось назвать 10 «Я»- или «не-Я»-феноменов, уровень абстрактности которых оценивался тремя независимыми экспертами. Было обнаружено, что формирование установки на восприятие «не-Я»-феноменов приводит к снижению уровня конструирования «Я»-феноменов при сохранении уровня конструирования «не-Я»-феноменов и наоборот. Также было проведено качественно-количественное сравнение «Я»- и «не-Я»-феноменов. Было выявлено, что «Я»-феномены, в среднем, конструируются на значимо более высоком уровне, чем «не-Я»-феномены. В силу специфики экспериментальной процедуры – осознанного разделения испытуемым феноменов на относящиеся к «Я» или «не-Я» (очевидно, не так часто проводящегося в повседневной жизни), более широкая экстраполяция полученных результатов требует проведения дополнительных исследований.
Teori Konstruktivistik dan Implikasinya dalam Pembelajaran
Authors: Suryana Ermis , Aprina Marni Prasyur , Harto Kasinyo
Published: July 2022

Melihat praktik pendidikan di negara Indonesia, konsep kontruktivistik ini belum sepenuhnya terwujud, padahal konsep tersebut telah tertuang di dalam kurikulum KTSP. Fakta lainnya tentang pendidikan di Indonesia adalah di tahun 2006, Program for International Student Assessment (PISA) mengungkapkan seberapa baik kesiapan seorang peserta didik yang berusia 15 tahun dalam menghadapi kehidupan, Indonesia menempati peringkat ke-50 dari 57 negara dalam bidang sains, membaca, dan matematika. Untuk itu penulis menganggap penting untuk membahas mengenai teori kontruktivistik dan mengimplikasinya dalam pembelajaran dan pendidikan di Indonesia. Teori konstruktivistik berbeda dengan teori belajar lainnya, implikasi teori konstruktivistik teori konstruktivistik dalam pembelajaran yaitu: peran siswa sebagai konsumen ide telah bergeser ke arah peran produser ide. Sementara itu, peran guru tergeser dari peran penghambat proses pembelajaran yang sering terjadi secara tidak sengaja menjadi peran fasilitator proses pembelajaran. Hasil penelitian menunjukkan pada intinya konsep kontruktivistik ini telah tertuang dalam kurikulum di Indonesia yaitu kurikulum KTSP, namun dalam praktiknya konsep tersebut belum diimplementasikan dengan baik. Untuk itu, perlu pembenahan dalam pendidikan di Indonesia dengan menggunakan pendekatan kontruktivistik ini agar peserta didik dapat mencapai potensinya secara maksimal dan pendidikan di Indonesia menjadi lebih maju dan berkualitas.