bluuebunny/crossref_metadata_2025 huggingface dataset:
Leveraging Very-High Spatial Resolution Hyperspectral and Thermal UAV Imageries for Characterizing Diurnal Indicators of Grapevine Physiology
Authors: Maimaitiyiming Matthew , Sagan Vasit , Sidike Paheding , Maimaitijiang Maitiniyazi , Miller Allison J. , Kwasniewski Misha
Published: October 2020

Efficient and accurate methods to monitor crop physiological responses help growers better understand crop physiology and improve crop productivity. In recent years, developments in unmanned aerial vehicles (UAV) and sensor technology have enabled image acquisition at very-high spectral, spatial, and temporal resolutions. However, potential applications and limitations of very-high-resolution (VHR) hyperspectral and thermal UAV imaging for characterization of plant diurnal physiology remain largely unknown, due to issues related to shadow and canopy heterogeneity. In this study, we propose a canopy zone-weighting (CZW) method to leverage the potential of VHR (≤9 cm) hyperspectral and thermal UAV imageries in estimating physiological indicators, such as stomatal conductance (Gs) and steady-state fluorescence (Fs). Diurnal flights and concurrent in-situ measurements were conducted during grapevine growing seasons in 2017 and 2018 in a vineyard in Missouri, USA. We used neural net classifier and the Canny edge detection method to extract pure vine canopy from the hyperspectral and thermal images, respectively. Then, the vine canopy was segmented into three canopy zones (sunlit, nadir, and shaded) using K-means clustering based on the canopy shadow fraction and canopy temperature. Common reflectance-based spectral indices, sun-induced chlorophyll fluorescence (SIF), and simplified canopy water stress index (siCWSI) were computed as image retrievals. Using the coefficient of determination (R2) established between the image retrievals from three canopy zones and the in-situ measurements as a weight factor, weighted image retrievals were calculated and their correlation with in-situ measurements was explored. The results showed that the most frequent and the highest correlations were found for Gs and Fs, with CZW-based Photochemical reflectance index (PRI), SIF, and siCWSI (PRICZW, SIFCZW, and siCWSICZW), respectively. When all flights combined for the given field campaign date, PRICZW, SIFCZW, and siCWSICZW significantly improved the relationship with Gs and Fs. The proposed approach takes full advantage of VHR hyperspectral and thermal UAV imageries, and suggests that the CZW method is simple yet effective in estimating Gs and Fs.
Coral Bleaching Detection in the Hawaiian Islands Using Spatio-Temporal Standardized Bottom Reflectance and Planet Dove Satellites
Authors: Xu Yaping , Vaughn Nicholas R. , Knapp David E. , Martin Roberta E. , Balzotti Christopher , Li Jiwei , Foo Shawna A. , Asner Gregory P.
Published: October 2020

We present a new method for the detection of coral bleaching using satellite time-series data. While the detection of coral bleaching from satellite imagery is difficult due to the low signal-to-noise ratio of benthic reflectance, we overcame this difficulty using three approaches: 1) specialized pre-processing developed for Planet Dove satellites, 2) a time-series approach for determining baseline reflectance statistics, and 3) a regional filter based on a preexisting map of live coral. The time-series was divided into a baseline period (April-July 2019), when no coral bleaching was known to have taken place, and a bleaching period (August 2019-present), when the bleaching was known to have occurred based on field data. The identification of the bleaching period allowed the computation of a Standardized Bottom Reflectance (SBR) for each region. SBR transforms the weekly bottom reflectance into a value relative to the baseline reflectance distribution statistics, increasing the sensitivity to bleaching detection. We tested three scales of the temporal smoothing of the SBR (weekly, cumulative average, and three-week moving average). Our field verification of coral bleaching throughout the main Hawaiian Islands showed that the cumulative average and three-week moving average smoothing detected the highest proportion of coral bleaching locations, correctly identifying 11 and 10 out of 18 locations, respectively. However, the three-week moving average provided a better sensitivity in coral bleaching detection, with a performance increase of at least one standard deviation, which helps define the confidence level of a detected bleaching event.
Terahertz Frequency-Scaled Differential Imaging for Sub-6 GHz Vehicular Antenna Signature Analysis
Authors: Solano-Perez Jose Antonio , Martínez-Inglés María-Teresa , Molina-Garcia-Pardo Jose-Maria , Romeu Jordi , Jofre-Roca Lluis , Ballesteros-Sánchez Christian , Rodríguez José-Víctor , Mateo-Aroca Antonio
Published: October 2020

The next generation of connected and autonomous vehicles will be equipped with high numbers of antennas operating in a wide frequency range for communications and environment sensing. The study of 3D spatial angular responses and the radiation patterns modified by vehicular structure will allow for better integration of the associated communication and sensing antennas. The use of near-field monostatic focusing, applied with frequency-dimension scale translation and differential imaging, offers a novel imaging application. The objective of this paper is to theoretically and experimentally study the method of obtaining currents produced by an antenna radiating on top of a vehicular platform using differential imaging. The experimental part of the study focuses on measuring a scaled target using an imaging system operating in a terahertz band—from 220 to 330 GHz—that matches a 5G frequency band according to frequency-dimension scale translation. The results show that the induced currents are properly estimated using this methodology, and that the influence of the bandwidth is assessed.
A Distributed Radio Beacon/IMU/Altimeter Integrated Localization Scheme with Uncertain Initial Beacon Locations for Lunar Pinpoint Landing
Authors: Mu Rongjun , Li Yuntian , Luo Rubin , Su Bingzhi , Shan Yongzhi
Published: October 2020

As a growing number of exploration missions have successfully landed on the Moon in recent decades, ground infrastructures, such as radio beacons, have attracted a great deal of attention in the design of navigation systems. None of the available studies regarding integrating beacon measurements for pinpoint landing have considered uncertain initial beacon locations, which are quite common in practice. In this paper, we propose a radio beacon/inertial measurement unit (IMU)/altimeter localization scheme that is sufficiently robust regarding uncertain initial beacon locations. This scheme was designed based on the sparse extended information filter (SEIF) to locate the lander and update the beacon configuration at the same time. Then, an adaptive iterated sparse extended hybrid filter (AISEHF) was devised by modifying the prediction and update stage of SEIF with a hybrid-form propagation and a damping iteration algorithm, respectively. The simulation results indicated that the proposed method effectively reduced the error in the position estimations caused by uncertain beacon locations and made an effective trade-off between the estimation accuracy and the computational efficiency. Thus, this method is a potential candidate for future lunar exploration activities.
Data-Driven Anomaly Detection Approach for Time-Series Streaming Data
Authors: Zhang Minghu , Guo Jianwen , Li Xin , Jin Rui
Published: October 2020

Recently, wireless sensor networks (WSNs) have been extensively deployed to monitor environments. Sensor nodes are susceptible to fault generation due to hardware and software failures in harsh environments. Anomaly detection for the time-series streaming data of sensor nodes is a challenging but critical fault diagnosis task, particularly in large-scale WSNs. The data-driven approach is becoming essential for the goal of improving the reliability and stability of WSNs. We propose a data-driven anomaly detection approach in this paper, named median filter (MF)-stacked long short-term memory-exponentially weighted moving average (LSTM-EWMA), for time-series status data, including the operating voltage and panel temperature recorded by a sensor node deployed in the field. These status data can be used to diagnose device anomalies. First, a median filter (MF) is introduced as a preprocessor to preprocess obvious anomalies in input data. Then, stacked long short-term memory (LSTM) is employed for prediction. Finally, the exponentially weighted moving average (EWMA) control chart is employed as a detector for recognizing anomalies. We evaluate the proposed approach for the panel temperature and operating voltage of time-series streaming data recorded by wireless node devices deployed in harsh field conditions for environmental monitoring. Extensive experiments were conducted on real time-series status data. The results demonstrate that compared to other approaches, the MF-stacked LSTM-EWMA approach can significantly improve the detection rate (DR) and false rate (FR). The average DR and FR values with the proposed approach are 95.46% and 4.42%, respectively. MF-stacked LSTM-EWMA anomaly detection also achieves a better F2 score than that achieved by other methods. The proposed approach provides valuable insights for anomaly detection in WSNs by detecting anomalies in the time-series status data recorded by wireless sensor nodes.
Towards Sustainable Cities: Utilizing Floating Car Data to Support Location-Based Road Network Performance Measurements
Authors: Braun Maximilian , Kunkler Jan , Kellner Florian
Published: October 2020

Road network performance (RNP) is a key element for urban sustainability as it has a significant impact on economy, environment, and society. Poor RNP can lead to traffic congestion, which can lead to higher transportation costs, more pollution and health issues regarding the urban population. To evaluate the effects of the RNP, the involved stakeholders need a real-world data base to work with. This paper develops a data collection approach to enable location-based RNP analysis using publicly available traffic information. Therefore, we use reachable range requests implemented by navigation service providers to retrieve travel times, travel speeds, and traffic conditions. To demonstrate the practicability of the proposed methodology, a comparison of four German cities is made, considering the network characteristics with respect to detours, infrastructure, and traffic congestion. The results are combined with cost rates to compare the economical dimension of sustainability of the chosen cities. Our results show that digitization eases the assessment of traffic data and that a combination of several indicators must be considered depending on the relevant sustainability dimension decisions are made from.
Sustainable Co-Creation Behavior in a Virtual Community: Antecedents and Moderating Effect of Participant’s Perception of Own Expertise
Authors: Rubio Natalia , Villaseñor Nieves , Yagüe MªJesús
Published: October 2020

Value co-creation by users in a virtual community is a key element of the community’s value and sustainability. This paper first analyzes the effect on co-creation behavior of (1) users’ altruism and (2) users’ interactivity with the different firms housed in the virtual community. It considers different sustainable co-creation behaviors based on intensity, distinguishing between moderate or high intensity, where recommendation of the service represents a moderate level of co-creation and co-innovation at a high level. Both behaviors are oriented not only to the firms housed in the virtual community, but also to the virtual platform itself. Second, the study proposes whether users’ perception of their expertise about the services and/or firms housed in the community exerts a moderating effect on the proposed modelling. Empirical contrast is performed using the virtual community TripAdvisor. This study contributes to current academic research on co-creation and sustainability. The results show that the user’s altruism is the determining factor in encouraging moderate sustainable co-creation behavior (recommendation of the service), whereas user–firm interactivity is the critical antecedent for fostering high-level co-creation in the form of co-innovation activities. The results vary, however, depending on the segment of virtual community users analyzed (expert vs. non-expert). This study also contributes to formulation of business strategies to foster sustainable co-creation behavior with greater repercussions for long-term participation in the virtual community.
Characteristics of a Novel Target Antigen against Myeloma Cells for Immunotherapy
Authors: Matsushita Maiko , Saito Saku , Yokoe Shinya , Ichikawa Daiju , Hattori Yutaka
Published: October 2020

Despite the availability of therapeutic treatments, multiple myeloma is an incurable haematological disorder. In this study, we aimed to clarify the role of CXorf48 as a therapeutic target in multiple myeloma. Based on a previously identified HLA-A*24:02-restiricted epitope from this novel cancer/testis antigen, we characterized the activities of cytotoxic T lymphocytes (CTLs) specific to this antigen against myeloma cells and evaluated the effects of demethylating agents in increasing antigen expression and enhancing the cytotoxic activity of CTLs. CXorf48 expression was examined by reverse transcription polymerase chain reaction (RT-PCR) using nine myeloma cell lines. Cell lines with low CXorf48 expression were treated by demethylating agents (DMAs), 5-azacytidine (5-aza), and 5-aza-2’-deoxycytidine (DAC) to evaluate gene expression using quantitative RT-PCR. Furthermore, CXorf48-specific CTLs were induced from peripheral blood mononuclear cells of HLA-A*24:02-positive healthy donors to evaluate antigen recognition using ELISpot and 51Cr cytotoxicity assays. CXorf48 was widely expressed in myeloma cells, and gene expression was significantly increased by DMAs. Furthermore, CXorf48-specific CTLs recognized DMA-treated myeloma cells. These findings suggest that CXorf48 is a useful target for immunotherapy, such as vaccination, in combination with demethylating agents for the treatment of patients with myeloma.
Use of Ensemble-Based Gridded Precipitation Products for Assessing Input Data Uncertainty Prior to Hydrologic Modeling
Authors: Pokorny Scott , Stadnyk Tricia A. , Lilhare Rajtantra , Ali Genevieve , Déry Stephen J. , Koenig Kristina
Published: October 2020

The spatial and temporal performance of an ensemble of five gridded climate datasets (precipitation) (North American Regional Reanalysis, European Centre for Medium-Range Weather Forecasts interim reanalysis, European Union Water and Global Change (WATCH) Watch Forcing data ERA-Interim, Global Forcing Data-Hydro, and The Australian National University spline interpolation) was evaluated towards quantifying gridded precipitation data ensemble uncertainty for hydrologic model input. Performance was evaluated over the Nelson–Churchill Watershed via comparison to two ground-based climate station datasets for year-to-year and season-to-season periods (1981–2010) at three spatial discretizations: distributed, sub-basin aggregation, and full watershed aggregation. All gridded datasets showed spatial performance variations, most notably in year-to-year total precipitation bias. Absolute minimum and maximum realizations were generated and assumed to represent total possible uncertainty bounds of the ensemble. Analyses showed that high magnitude precipitation events were often outside the uncertainty envelope; some increase in spatial aggregation, however, enveloped more observations. Results suggest that hydrologic models can reduce input uncertainty with some spatial aggregation, but begin to lose information as aggregation increases. Uncertainty bounds also revealed periods of elevated uncertainty. Assessing input ensemble bounds can be used to include high and low uncertainty periods in hydrologic model calibration and validation.
Medical Aspects of Ensuring Safety of the ISS-60/61/62 Crew Members in a Space Flight (Express Analysis).
Authors: Bogomolov V.V. , Pochuev V.I. , Alferova I.V. , Khorosheva E.G. , Krivolapov V.V.
Published: October 2020

The paper shows results of medical support of the ISS-60/61/62 Expedition and gives a brief description of the medical support system. As well, the paper sums up results of the implementation of the program for monitoring of cosmonauts' health state and use of onboard means meant for maintaining the health and performance of humans in space.
Main Results of Training and Activity of the ISS Crew for Expedition 60/61/62 When Carrying Out the Mission Plan.
Authors: Skripochka O.I. , Oreshkin G.D. , Kondrat A.I. , Medvedev А.А. , Saburov P.A.
Published: October 2020

The paper represents the ISS crew for Expedition 60/61/62 as well as main tasks and results of training. The great attention is paid to the results of the crew’s activities aboard the “Soyuz MS-15” manned transport vehicle (MTV) and International Space Station (ISS). The preliminary analysis of the implementation of the Russian scientific applied research and experiments is made. Extravehicular operations (EVA) under the programs of the ISS USOS are also briefly represented.
Synthesis and properties of composite materials based on zinc oxide nanoparticles in an insulating matrix
Authors: Karankova S. Y. , Tikhonov I. A. , Chubenko E. B.
Published: October 2020

A composite material based on zinc oxide nanoparticles synthesized by the chemical hydrothermal method and a polymer insulated matrix of sodium silicate was obtained. Free zinc oxide nanoparticles were formed by heating an equimolar solution of zinc nitrate and hexamethylenetetramine with different pH values (3–5). Nanoparticles were introduced into an aqueous sodium silicate solution and applied on a silicon substrate by centrifugation. Using scanning electron microscopy, we studied the structure and morphology of zinc oxide nanoparticles on a silicon substrate in unbound state and after their introduction into the sodium silicate matrix. It was found that the obtained particles have a hexagonal crystal lattice and a bimodal size distribution. After introduction in the matrix of sodium silicate, only smaller zinc oxide nanoparticles with an average diameter of 45 nm remain in it. Studying of the photoluminesclence spectra of a composite material, including zinc oxide nanoparticles obtained at different pH values of the initial solution, showed the presence of exciton and defectrelated photoluminescence bands with intensity’s maximums located at 383 and 590 nm, respectively. Zinc oxide nanoparticles in the stabilizing matrix of sodium silicate exhibit a higher relative intensity of exciton photoluminescence than unbound particles. The highest value of the relative intensity of exciton photoluminescence was achieved for a composite material including zinc oxide nanoparticles synthesized at pH=3,35 of the initial solution. The resulting composite materials can be used in optoelectronic and photovoltaic devices, and as an optical medium of non-cavity lasers.
Ontological approach to Chinese text processing
Authors: Longwei Q.
Published: October 2020

To implement natural language user interface and an intelligent answer to questions, the knowledgebased semantic model for Chinese language processing is proposed. The article gives careful consideration to the existing methods and various knowledge bases for natural language processing. The analysis of these methods has led to the conclusion that in natural language processing, the knowledge base is the most fundamental and crucial part. The knowledge base makes it possible to ensure processing of a natural language based on initially described knowledge and to explain the processing operations. By virtue of the analysis of various methods for constructing knowledge bases about the English and Chinese languages, an ontological approach to the Chinese language processing was proposed. The Chinese language processing model has two main aspects: the design of knowledge base about the Chinese language and the development of ontology-based knowledge processing machine. The proposed approach is aimed at developing a semantic model of knowledge on the Chinese language. As a stage in the implementation of the approach, I designed the ontology of the Chinese language that can be applied for further processing of the language. This paper considers the preliminary version of the ontology and the principle of building a knowledge base about the Chinese language. There are no uniform standards and evaluation system for designing an ontology. Expansion, refinement and evaluation of the ontology require further research.
ANALYSIS OF THE RESULTS OF LABORATORY STUDIES OF ORAL FLUID AND BLOOD SERUM OF PATIENTS IN THE RETENTION PERIOD OF ORTHODONTIC TREATMENT
Authors: Stepanov GV V , Ayupova IO O , Ulyanova LG G
Published: October 2020

In the course of complex treatment of patients with dentomaxillofacial abnormalities, two periods are distinguished: the period of active apparatus treatment and the retention period (consolidation of the results of orthodontic treatment). Ensuring the stability of the treatment results in patients with abnormalities of occlusion and irregular position of the teeth depends on the correct diagnosis and treatment plan. There are special methods, confirming the effectiveness of orthodontic treatment (anthropometric, radiological, photometric). Analysis of the results of laboratory studies of oral fluid and blood serum of patients who are in the retention period allows evaluation of the effectiveness of treatment and the stability of results. Aim - studying of the results of laboratory indicators of oral fluid and blood serum of patients in the retention period of orthodontic treatment. Material and methods. The total number of examined orthodontic patients was 156. At the first stage of the study, 96 patients were examined and divided into 3 groups. At the second stage, 60 people were examined (4th group). We performed the diagnostics of gingival crevicular fluid as the most promising material in terms of diagnostic capabilities, noninvasiveness and the ease of obtaining samples, and the possibility of retaking of biomaterial. All the patients underwent the study of biochemical and immunological parameters of blood serum, oral and gingival fluid. Results. At the end of treatment, biochemical indices are aligned, and osteoblastic activity decreases, which indicates the completion of the active adjustment and normalization of bony tissue.
COMPOSITION OF ESSENTIAL OIL OF TANACETUM VULGARE L. FROM SAMARA REGION
Authors: Kurkin V A , Sazonova O V , Kurkina A V , Ryazanova T K , Khusainova A I
Published: October 2020

Aim - to analyze the essential oil isolated from the tansy (Tanacetum vulgare L.) flowers harvested from the spontaneous flora of Samara region. Materials and methods. The analysis was made on head flowers of Tanacetum vulgare harvested from the spontaneous flora of Samara region during the flowering stage (July), in 2016. The isolation of the essential oil was made in accordance with the Pharmacopeia of the Russian Federation XIIIth Edition. The essential oil was analyzed using a gas chromatograph coupled with mass-spectrometer apparatus. GCMS analysis was performed using an Agilent Technologies 7820F gas-chromatograph, series MSD, Agilent 5975. Results. It was determined that the major compounds of essential oil are represented by 2 isomers of thujone, eucalyptole (1,8-cineole) and yomogi-alcohol. According to the results of headspace analysis, the main identified components were artemisia alcohol, sabinene, eucalyptole (1,8-cineole). Conclusion. The knowledge of phytochemical characteristics of Tanacetum vulgare L. is important for the correct identification of the plant material for medical purposes.
EVALUATION OF EFFECTIVENESS OF ACLIDINIUM BROMIDE FOR PATIENTS WITH OCCUPATIONAL CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
Authors: Vakurova NV V , Azovskova TA A
Published: October 2020

Aim - evaluation of effectiveness and safety of the innovative medicinal product aclidinium bromide for patients with occupational COPD (chronic obstructive pulmonary disease). Materials and methods. The research was performed during 2015-2016 in the Samara Regional Center for Occupational Pathology. The study included 44 patients with the diagnosis of occupational chronic obstructive pulmonary disease. The diagnosis was based on the history of professional data, sanitary characteristics of working conditions, and complete clinical, functional and instrumental examination of the patients. The patients were randomly divided into two groups: 22 patients were given 322 micrograms of aclidinium bromide via inhalation twice a day during 24 weeks, while 22 patients from the comparison group were given 50 micrograms of glycopyrronium bromide once daily. The respiratory function test was carried out both before and after the treatment; the dynamics of dyspnea was measured and the quality of patients’ life was estimated. The following aspects were examined: the quantity of days when emergency medicinal treatment was not required; the quantity of required daily inhalations of rescue medications; the frequency of exacerbations; the period before the first exacerbation happens; compliance; adverse drug reactions. Statistical processing of the data was performed using SPSS 21 software package. Results. Aclidinium bromide has advantages over glycopyrronium bromide concerning the following aspects: functional indices (FEV1 forced expiratory volume during the first second), clinical data (dyspnea), quality of patients’ life, frequency of exacerbations, the period before the first exacerbation happens, and patients’ compliance. Conclusion. Aclidinium bromide has proven to be an effective and safe medication for medical treatment of patients who suffer from moderately severe occupational COPD.
BRAIN-COMPUTER INTERFACE: FUNDAMENTAL AND CLINICAL ASPECTS OF DEVELOPMENT AND IMPLICATION OF THE TECHNOLOGY
Authors: Kolsanov AV V , Avdeeva EV V
Published: October 2020

The article discusses the results of the III International Scientific and Practical Conference "Brain-Computer Interface: Science and Practice. Samara - 2017 ". The review covers the scientific studies dealing with fundamental and applied aspects of brain research and development of brain-computer interfaces (BCI) presented at the conference by leading domestic and foreign scientists. Clinical application of BCI is discussed in terms of neurorehabilitation of patients with motor and speech disorders, as well as the possibility of its use in diagnosis and correction of psychiatric diseases and disorders.
EPIDEMIOLOGICAL DATA ON LARYNGEAL PAPILLOMATOSIS IN THE MOSCOW REGION
Authors: Mustafaev D M , Egorov V I
Published: October 2020

Im - to evaluate the prevalence of laryngeal papillomatosis in adults and children, to analyze the structure of the disease and to generalize the dynamics of the disease in the Moscow region. Materials and methods. The authors have carried out an epidemiological analysis of laryngeal papillomatosis in the Moscow region in the period from 2008 to 2014. Results. According to the received data, the prevalence of laryngeal papillomatosis in the Moscow region is 2.3 per 100000 children and 1.95 per 100000 adults. Discussion. Based on the epidemiological data, the significance of laryngeal papillomatosis in adults and children has been proved, and increased morbidity has been revealed. Laryngeal papillomatosis is one of the most important social and health problems. Taking into account the significant increase in the incidence of laryngeal papillomatosis in adults and children, it is necessary to focus on the organization of preventive measures aimed not only at preventing relapses, but also against the spread of HPV infection among healthy population in the Moscow region. To conclude, it is necessary to carry out annual analysis of the structure and course of the disease in the Moscow region.
VOICE REHABILITATION OF PATIENTS AFTER LARYNGECTOMY BY MEANS OF TRACHEOESOPHAGEAL SHUNTING AND VOICE PROSTHETICS
Authors: Chujkova A Yu , Vozdvizhenskij M O , Makhonin A A
Published: October 2020

Aim - to evaluate the effectiveness of voice rehabilitation with the use of voice prosthesis, and to review the existing methods of voice rehabilitation with their advantages and disadvantages in order to define the most effective one. Materials and methods. 26 clinical cases include patients aged 54-70 years who underwent laryngectomy as a part of the throat cancer treatment. Voice prostheses were used for their rehabilitation. Results. Tracheoesophageal shunting with voice prosthesis has remarkable advantages over the other methods of restoring the normal voice function.
CHRONIC INFLAMMATION OF THE TONSILS ASSOCIATED WITH EPSTEIN-BARR VIRUS
Authors: Baryshevskaya L A , Vladimirova T Yu , Zeleva O V , Koldova E V
Published: October 2020

Aim - to identify the prevalence of chronic tonsillitis in the Samara region and the causes of its recurrence. Materials and methods. The authors analyzed the frequency of occurrence of chronic tonsillitis among the patients of the Samara Diagnostic Center for the period from 2011 to 2016, the frequency of quinsy and paratonsillar abscesses. Middle-aged and elderly people with signs of chronic tonsillitis were examined for the presence of Epstein-Barr virus. Results. 56 adult and elderly patients aged from 44 to 75 years (18 men - 31% and 38 women - 65.5%) underwent additional examination of saliva and blood for the presence of Epstein-Barr virus. The analyses were taken on an empty stomach in the morning. When taking saliva, hygienic treatment of the oral cavity was not carried out. Saliva was investigated by a qualitative method of PCR diagnostics. We also performed serodiagnostic assay by ELISA. DNA of Epstein-Barr virus was discovered in 16 patients (27.6%), IgG antibodies to nuclear antigen (EBNA) - in 13 patients (22%), and 1 patient (1.7%) had IgM antibodies to capsid antigen (VCA). Thus, 1.7% of Epstein-Barr virus was diagnosed at an early stage, 22% of patients had infection in the past and 27.6% had recent infection. Conclusions. Presented evidence suggests that it is necessary to combine examination of the content of tonsillar lacunae with PCR and ELISA diagnostics for Epstein-Barr virus not only in young patients of working age with chronic tonsillitis, but also in middle-aged and elderly patients with chronic tonsillitis in order to improve the efficiency and quality of the treatment at the stage of outpatient visit.
THE USE OF VESTIBULAR REABILITATION IN PATIENTS WITH VIOLATIONS OF THE VESTIBULAR ANALYZER
Authors: Nasretdinova M T , Karabaev H E
Published: October 2020

Aim - to present the results of the observational program, the purpose of which was to reduce visual disorders associated with vestibular dysfunction, and restore balance, thereby reducing the risk of falls. Materials and methods. 46 patients took part in the observational study. Determination of the optimal duration of vestibular rehabilitation in patients with unilateral non-progressive peripheral vestibular disorder. Results. It was found that the optimal duration of treatment is no less than 2 months.
RISK FACTORS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA: RISK STRATIFICATION AND TREATMENT TACTICS
Authors: Simerzin Vasilii V. , Krasovskaya Margarita A. , Gagloev Anton V.
Published: October 2020

This review focuses on traditional and occasional risk factors in patients with familial hypercholesterolemia (FH) that influence their medical condition along with the level of the extreme hypercholesterolemia and their age (time of exposure to hypercholesterolemia). The risk factors in question can define the patients' stratification in groups of high and extreme risk, assist in treatment tactics and strategy.
SCHOOLCHILDREN AND ADOLESCENTS HEALTH PROBLEMS IN SAMARA: CURRENT TRENDS
Authors: Poretskova Galina Yu. , Tyazheva Alena A. , Rapoport Irina K. , Voronina Evgeniya N.
Published: October 2020

Objectives - to reveal the health dynamics in schoolchildren in Samara, to identify the types of pathological conditions. Material and methods. We used data from school medical records of pupils in grades 1-4 (2070 children), clinical examination of adolescents aged 14 years (788 people), and data of dynamic monitoring of schoolchildren aged 15-17 years (1002 people). Statistical processing was carried out according to the standard procedure using a package of Windows applications (Excel, Word), Statistica. Results. We revealed the decrease in the number of healthy children from 1st to 4th grade from 27.2% to 8.8%, and an increased quantity of pupils with functional and chronic health conditions. The morbidity analysis of the 1st grade schoolchildren demonstrated the high ranks of nervous system diseases, mental and behavioral disorders (289.3% and 241.6%), the third place was taken by musculoskeletal system pathologies (200.0%), in the fourth - diseases of the respiratory system (148.8%), in the fifth - diseases of the eye (144.1%). In the 4th grade the leader was the diseases of the musculoskeletal system (548.5%), diseases of the eye (374.4%), diseases of the digestive system (167.4%). In adolescents the pathology of musculoskeletal system was most often registered (376.0%), vision impairment was the following (346.6%). Conclusion. In respect to the nosology and dynamics of health problems in schoolchildren it is necessary to identify the risk factors and to implement targeted prevention programs.
Prognosis of the combination therapy results in patients with synchronous metastases of colorectal cancer
Authors: Kozlov S. V , Kaganov O. I , Moryatov A. A , Kozlov A. M , Borisov A. P
Published: October 2020

Objectives - to optimize the indications for radiofrequency thermal ablation in patients with synchronous multiple metastases of colorectal cancer to the liver on the basis of prognostic treatment results. Material and methods. The study group included 78 patients with colorectal cancer with synchronous multiple bilobar liver metastases, who have underwent combined treatment in the period of 2007- 2015, such as cytoreductive surgery removing the primary intestinal tumor in combination with RFA of metastases in the liver, followed by chemotherapy. Results. A computer program for preoperative risk assessment of disease progression was developed and introduced in clinical practice. It is based on the results of the analysis of the factors, predicting the risk of relapse during the first year after cytoreductive surgery with RFA of synchronous multiple CRC liver metastases. Conclusion. The index of metastatic liver damage (the product of the sum of the diameters of metastatic liver lesions by their number), the mutational status of the KRAS gene, CEA values are significant factors in predicting the progression of the disease, which can optimize indications for radiofrequency thermal ablation in the treatment of patients with stage IV CRC with synchronous metastases to the liver.
Features of microcirculation and effectiveness of conservative therapy in exacerbation of chronic tonsillitis
Authors: Ovchinnikov Andrey Y. , Burenkov Evgenii S.
Published: October 2020

Objectives - to study the characteristics of microcirculation in patients with chronic tonsillitis, caused by Streptococcus pyogenes with confirmed sensitivity to the group of inhibitor-protected penicillins. Material and methods. The study of micro vascular blood flow in the tonsils was performed with laser Doppler flowmetry, using the multifunctional diagnostic complex "LAKK-M" (Russia, 2010). Results. The analysis of the microcirculation parameters of patients in group I showed significant changes in the functioning of their micro vascular blood flow, if compared to patients in the control group. The intensity of blood flow in the tonsils was significantly less in the individuals with low sensitivity to antibacterial therapy. Conclusion. 1. In case of the clinical inefficacy of the antibacterial therapy in patients with microflora, sensitive in vitro to the same antibiotics, it is necessary to study the microcirculation in their tonsils. 2. Perfusion indicators can be used as an additional express-criterion for predicting the effectiveness of the conservative therapy. 3. If there is a significant change in the micro vascular blood flow, it is necessary to consider the possibility of surgical treatment of patients with chronic tonsillitis.
The main aspects of improvement of emergency medical care for patients with acute coronary syndrome
Authors: Breusov Aleksey V. , Kharchenko Vladimir V. , Breusov Dmitriy A.
Published: October 2020

Objectives - to develop the main strategies of emergency medical care improvement for patients with acute coronary syndrome, in order to to reduce the morbidity and mortality in the population of a large industrial region. Material and methods. The study was conducted on the basis of the Moscow regional ambulance station. We used the content analysis, logical, system analysis, the method of mathematical statistics. Results. In the period 2017-2018, in the region's population, there is a tendency for decrease in the number of calls for ambulance teams caused by acute coronary syndrome. During the analyzed period, we noticed the reduction of the number of cases of pre-hospital thrombolytic therapy (by 17.5%). The response time to the patient's call not more than 20 minutes was observed in 92.9% of cases, the number of lethal outcomes in presence of the ambulance team decreased by 4. 6%. The results can be explained by the dynamic development of the infrastructure of cities and districts of the Moscow Region, by the improvement of road networks, by the complete renewal of the service's motor vehicle fleet, and by the opening of a number of new specialized medical institutions. A set of medical and organizational measures has been developed and put into practice in the ambulance service of the region, aimed at further improvement of the system of ambulance care for patients with acute coronary syndrome at the prehospital stage. Conclusion. The mortality reduction, preservation and improvement of public health can be achieved only through the comprehensive sustainable development of the region’s infrastructure, improvement of the organizational structure of the emergency medical service, mandatory use of algorithms and standards for the provision of medical care to patients at all stages.
Investigating judge as a new figure in the Kyrgyz Republic criminal procedure
Authors: Shestakova Sof'ya , Imanalieva Uulzhan
Published: October 2020

The article iis devoted to the research of the institution of investigative judge introduced into the criminal procedure of the Kyrgyz Republic in 2019. The authors analyze the conceptual foundations of this institution, its procedural significance, as well as the legal model under Kyrgyz legislation in its comparative perspective with the legislation of Germany and some former Soviet republics. Two main achievements: the organizational and functional isolation of an investigating judge during the criminal procedure and granting them the power of deposition are seen by the authors as advantages of the Kyrgyz model of the institution of an investigative judge. The former is aimed at guaranteeing the objectivity, impartiality and neutrality of the judge considering the case on the merits, who is discharged judicial control in pre-trial procedure nowadays. The latter is aimed at implementing for the prosecution and defense the right to be equal parties of procedural opportunities to participate in evidence as an integral element of the adversarial principle.
Actual issues of systematization of scientific knowledge on the conditions of shot in the forensic ballistics
Authors: Latyshov Igor' , Samuylenko Fedor
Published: October 2020

In this research, there was considered a challenge of constructing a system of scientific knowledge of the shot conditions in judicial ballistics. It was observed that there are underlying factors that are intended to ensureits [scientific knowledge] consistency: identification of the list of shot conditions, which require consideration when solving expert-level research tasks on weapons, cartridges and traces of their action; determination of the communication systems in the course of objects’ interaction, which present the result of exposure to the conditions of the shot; classification of the shot conditions based on the grounds significant for solving scientific and practical problems. The article contains the characteristics of a constructive, functional factor (condition) of weapons and cartridges influence, environmental and fire factors, the structure of the target and its physical properties, situational and spatial factors, and projectile energy characteristics. Highlighted are the forms of connections formed in the course of objects’ interaction, proposed are the author’s classifications of forensically significant shooting conditions with them being divided on the basis of the following criteria: production from the object of interaction, production from a natural phenomenon, production method, results weapon operation and utilization, duration of exposure, type of structural connections between interaction objects, number of conditions that apply when firing and the forming traces.
Psychological features of the socio-psychological adaptation of employees of internal affairs bodies with a different level of personal adaptation potential
Authors: Popinako Ekaterina , Goncharova Natal'ya
Published: October 2020

Socio-psychological adaptation of the employee is an important condition for the success of professional activities, determining the effectiveness and reliability of the subject in performing operational tasks. The scientific significance of the problem is actualized in the professions of social orientation and requires not only physiological adaptations, but analysis of prospects predict the dynamics of adaptation, a constructive interaction and cooperation in socio-professional environment. Current empirical studies show that law enforcement problems of professional adaptation involve a lot of social regulatory factors, value and moral content. In the presented results of empirical research the peculiarities of socio-psychological adaptation of employees of internal Affairs bodies with different level of personal adaptive capacity are discussed. Statistical analysis of indicators of two groups of adapted and unadapted staff allowed us to establish reliably significant differences in the adaptation on physical, psychological and social levels. It was revealed that employees with low levels of adaptive capacity are different in asthenic reactions, neuropsychological instability, emotional discomfort, severity of negative emotional state. The overall profile of socio-psychological adaptation is characterized by low level of behavioral self-regulation and communicative potential difficulties in establishing a constructive relationship, deconditioning disorders. It was found that employees with a high level of personal adaptive capacity are different in activity and performance, neuro-psychological stability, the capacity for behavioral self-control, communicative abilities and moral normativity. Indicators of socio-psychological adaptation demonstrate the ability to adequate perception of social norms, the availability of professional motives in the activities, alignment of personal interests with the interests of the service activities, goodwill in the relationship, cooperation and responsibility.
Personnel support of the police of the Irkutsk province during the period of anti-Bolshevik power in 1918–1919
Authors: Sinichenko Vladimir , Kaveckiy Dmitriy
Published: October 2020

The article aims to study the activities of the police of the Irkutsk province during the Civil War. The object of the study in the article was the units of the people’s (civilian) police, created in early March 1917 and acting on the basis of the Regulation adopted on April 17, 1917 by the Provisional Government. On October 28 (November 10), 1917, the PKIB of the RSFSR issued a new decree «On the Workers’ Police», but after the overthrow of Soviet power in the summer of 1918 in the east of the country, the eastern regions returned to the Regulation of April 17. The functioning of the police in 1918–1919, based on the principles of the Provisional Government and became the object of analysis in this work. The subject of the study is the personnel work carried out during this period in the law enforcement agencies of the Baikal region. Along with general scientific methods (analysis, synthesis, deduction, induction etc.), the work used problem-chronological and comparative methods that revealed the dynamics of historical events in Eastern Siberia, their impact on politics, on decision-making, and revealed similarities and differences in the forms, organization and manifestation of police actions operating in eastern Russia in the indicated historical period of time. It is concluded that the activities of the authorities of the Irkutsk province to recruit police units were unskilled. Of course, leaders at various levels, to the extent of their limited resources, tried to strengthen the public order authorities, but the lack of systemic organization of law enforcement work had a negative impact on the activities of the police. Neither the Omsk government, nor the civilian and military authorities of the Irkutsk province, could provide at the proper level not the material supply of the police, nor its personnel support. As a result, the police of the Irkutsk province not only did not defend the authorities against the Bolsheviks, but also could not cope with the functions of law enforcement. The increase in criminal criminality in 1918 and 1919 is recorded by all printed publications of the Irkutsk province of that time, as well as statistical reports of the provincial police.
The Utilization of Sweet Potatoes as Prebiotics on The Performance of Lactobacillus sp. in The Vanamei Shrimp Digestion (Litopenaeus vannamei)
Authors: Theresia Maria , Aslamyah Siti , Sriwulan Sriwulan
Published: October 2020

The use of probiotics (Lactobacillus  sp.) in feed is one alternative that is done to improve immunostimulants, growth stimulants, and can be used as a balance of microorganisms in digestion. This study aimed to evaluate the growth performance of vanamei shrimp fed with the addition of Lactobacillus  sp. with sweet potatoes in feed. This study used a completely randomized design (CRD) with 4 treatments and 3 replications. The treatment was by feeding with different sweet potato concentrations: A) The dose of sweet potato in feed was 0% (as control); B) The dose of sweet potato in feed was 10%; C) 1The dose of sweet potato in feed was 15%; and D) The dose of sweet potato in feed was 20%. Data were analyzed using variance analysis (ANOVA) and continued with W-Tuckey's further test. The research parameters were digestive enzyme activity, nutrient digestibility, and growth. The results of the variance analysis showed the addition of various sweet potato concentrations with Lactobacillus sp. has no significant effect (p> 0.05) of the growth rate. The specific growth rate of vannamei shrimp ranges from 3.06 to 3.23% / day. Based on the results of the analysis on the utilization of sweet potatoes as a prebiotic on the performance of Lactobacillus sp. in the vannamei shrimps (Litopenaeus vannamei) digestive tract can be concluded that the growth performance does not have a significant effect after being fed with the addition of Lactobacillus sp. and sweet potatoes in feed.
Keywords: Enzymes, Digestion, Growth, Lactobacillus sp., Prebiotic, Probiotic.