bluuebunny/crossref_metadata_2025 huggingface dataset:
A Sleep Analysis of Elite Female Soccer Players During a Competition Week
Authors: Thomas Craig , Jones Helen , Whitworth-Turner Craig , Louis Julien
Published: March 2021

Purpose: (1) To compare the sleep of female players from a professional soccer team to nonathlete controls across an in-season week and (2) to compare the sleep of core and fringe players from the same team on the night after a match to training nights. Methods: Using an observational design, 18 professional female soccer players and 18 female nonathlete controls were monitored for their sleep via wristwatch actigraphy across 1 week. Independent-sample t tests and Mann–Whitney U tests were performed to compare sleep between groups, while an analysis of variance compared sleep on training nights to the night after a match. Results: Soccer players had significantly greater sleep duration than nonathlete controls (+38 min; P = .009; d: 0.92), which may have resulted from an earlier bedtime (−00:31 h:min; P = .047; d: 0.70). The soccer players also had less intraindividual variation in bedtime than nonathletes (−00:08 h:min; P = .023; r: .38). Despite this, sleep-onset latency was significantly longer among soccer players (+8 min; P = .032; d: 0.78). On the night after a match, sleep duration of core players was significantly lower than on training nights (−49 min; P = .010; d: 0.77). In fringe players, there was no significant difference between nights for any sleep characteristic. Conclusions: During the in-season period, sleep duration of professional female soccer players is greater than nonathlete controls. However, the night after a match challenges the sleep of players with more match involvement and warrants priority of sleep hygiene strategies.
The age of dust—A new hydrological indicator in arid environments?
Authors: Turner Simon , Handley Heather , Hesse Paul , Schaefer Bruce , Dosseto Anthony
Published: March 2021

Dust plays important roles in the environment, and there has been much interest in the formation, provenance, and age of the world's dust deposits. Ongoing debates are concerned with the importance of glacial grinding versus eolian abrasion and fluvial transport in the formation of silt-sized particles. Short-lived uranium-series isotopes afford new insights because they can be used both for provenance fingerprinting and for constraining the integrated age of chemical and physical weathering and subsequent transport and storage of sediments. Here we present trace element and Sr, Nd, and U-series isotope analyses from a number of Australian dusts and suspended river sediments remobilized during floods a year later. The inferred ages of the Australian dust appear to be linked to aridification and the loss of inland megalakes ∼30–120 k.y. ago. This provides preliminary evidence that the age of dust may provide a new hydrological indicator in arid environments.
Efficacy of Traditional Chinese Medicine Combined with Selective Serotonin Reuptake Inhibitors on the Treatment for Parkinson’s Disease with Depression: A Systematic Review and Meta-Analysis
Authors: Feng Si-Tong , Wang Xiao-Le , Wang Ya-Ting , Yuan Yu-He , Li Zhi-Peng , Chen Nai-Hong , Wang Zhen-Zhen , Zhang Yi
Published: March 2021

Depression is a common neuropsychiatric symptom of Parkinson’s disease (PD), resulting in a lower quality of life and cognitive impairment in PD patients. Traditional Chinese medicine (TCM) formulas have been widely used in neurodegenerative disease and neuropsychic disorders to improve life quality of patients in ethnomedicine. TCM formulas combined with selective serotonin reuptake inhibitors (SSRIs) also have a positive effect on depressed PD compared with SSRIs as reported by several clinical studies. However, the results are discordant and failed to be conclusive. We aim to evaluate the efficacy of TCM formulas combined with SSRIs for depressed PD in this systematic review. We searched literatures from PubMed, Web of Science, Medline, Embase, Google Scholar, Chinese National Knowledge Infrastructure, Wanfang Database, and VIP Information Database before July 2020. We included randomized controlled trials investigating the efficacy of TCM formulas combined with SSRIs on depressed PD patients. This analysis was according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. Eleven randomized clinical trials involving 861 subjects were enrolled in this analysis. The overall results showed that TCM formulas combined with SSRIs significantly improved the depression score [weighted mean difference (WMD): −4.920, 95% confidence interval (CI): (−5.999, −3.840); [Formula: see text]¡ 0.001] and had a statistical significance on Unified Parkinson’s Disease Rating Scale II score [WMD: −1.209, 95% CI: (−1.561, −0.857); [Formula: see text] < 0.001]. Furthermore, we observed that Chai-Hu-Shu-Gan Powder combined with SSRIs had a significant improvement on the depressive symptom in PD compared to the SSRIs alone [WMD: −5.390, 95% CI: (−7.66, −3.11); [Formula: see text] < 0.001]. No severe side events were reported in these included trials. This systematic review provided the evidences that TCM formulas combined with SSRIs might be helpful and safe in the treatment of depression of PD, including Chai-Hu-Shu-Gan Powder. Also, more randomized double-blinded trials with reliable design are required in the future.
Cosmological consequences of modified Friedmann equations according to holographic equipartition law
Authors: Jawad Abdul , Saleem Sidra , Qummer Saba
Published: March 2021

We examine thermodynamically an extra driving term for the flat universe by applying Sharma Mittal entropy to Padmanabhan’s holographic equipartition law. Deviations from the Bekenstein–Hawking entropy by using this law, we generate an extra driving in the acceleration equation. By using the constant and parametrized equation of state parameter, we investigate the different cosmological parameters like deceleration parameter, squared speed of sound, Om-diagnostic and statefinder parameter through graphical approach. We observe compatible results with current observational data in both models. Generalized second law of thermodynamics also remains valid in both cases.
On w-Convergence and s-Convergence in Intuitionistic Fuzzy Pseudo Normed Spaces
Authors: Dinda Bivas , Ghosh Santanu Kumar , Samanta T. K.
Published: March 2021

This paper analyzes the study of convergence in intuitionistic fuzzy pseudo normed linear space (IFPNLS) in two different directions. First, we study the weaker (more general) concept of convergence in IFPNLS called w-convergence and characterize the principal IFPNLS in which w-convergence and convergence are equivalent. Then we study a stronger concept of convergence said to be [Formula: see text]-convergence in IFPNLS and investigate the properties of s-convergence.
Anodic Dissolution of Copper in the Acidic and Basic Aluminum Chloride 1-Ethyl-3-methylimidazolium Chloride Ionic Liquid
Authors: Reidy Lorlyn , Wang Chen , Hussey Charles L.
Published: March 2021

The anodic dissolution of copper was investigated at a copper RDE in the Lewis acidic and basic composition regions of the room-temperature AlCl3-EtMeImCl ionic liquid (IL) to assess the utility of chloroaluminate liquids as solvents for the electrochemical machining and electropolishing of copper. In the Lewis acidic IL (60 mol % AlCl3), the dissolution of Cu0 proceeds under mixed kinetic-mass transport control with an exchange current density of 7.00 mA cm−2 at 306 K and an apparent activation free energy of 19.7 kJ mol−1. A formal potential of 0.843 V was obtained for the Cu+/Cu0 reaction from potentiometric measurements. In the basic IL (< 50 mol % AlCl3), potentiometric measurements showed that the oxidation of Cu0 resulted in the formation of [CuCl2]−. In this case, the formal potential of the [CuCl2]−/Cu0 reaction is −0.412 V. At small positive overpotentials, the reaction exhibited mixed control and was first order in the chloride concentration, indicating that only a single Cl− is involved in the RDS. However, at more positive overpotentials, the reaction transitions to mass transport control, and a well-defined limiting current is observed for the anodization process. This limiting current scales linearly with the free chloride concentration in the IL.
Fluidity Influencing Factors Analysis and Ratio Optimization of New Sealing Materials Based on Response Surface Method
Authors: Guo Xin , Xue Sheng , Li Yaobin , Zheng Chunshan , Yang Gege
Published: March 2021

The borehole sealing material is one of the key factors affecting the gas drainage effect of a borehole. This paper takes the compressive strength, fluidity, expansion rate, and setting time of the sealing material as the main research indicators and explores the influence of each key influencing factor on the performance of the high-fluid sealing material through the single factor experiment method. Using the Design-Expert 8.0.5 Trial software designed orthogonal experiments and establishing a quadratic model between liquidity and each test factor, which showed the impact of each key factor on the fluidity. Finally, by adjusting the amount of admixtures, the optimal ratio of high-fluidity borehole sealing materials was obtained. The results showed that the key factors had the following order of significance:

water
–
cement
 
reducing
 
agent
>
water
–
cement
 
ratio
>
retarder
>
expansion
 
agent

. With the water-cement ratio and the amount of water reducing agent increase, the fluidity of the material will increase; and with the increase of the retarder and expansion agent, the fluidity will decrease. In actual use, the fluidity is the main factor, but the expansion rate, compressive strength, and setting time are also considered. The optimal percentages were found for the high-fluidity borehole sealing material: a water-cement ratio of 1, along with 0.03% retarder, 0.5% water reducer, and 8% expansion agent. These research results could provide a reference for improving the performance of gas drainage borehole sealing materials and enhancing the effect of gas drainage.
Ndufs1 Deficiency Aggravates the Mitochondrial Membrane Potential Dysfunction in Pressure Overload‐Induced Myocardial Hypertrophy
Authors: Zou Rongjun , Tao Jun , Qiu Junxiong , Shi Wanting , Zou Minghui , Chen Weidan , Li Wenlei , Zhou Na , Wang Shaoli , Ma Li , Chen Xinxin
Published: March 2021

Mitochondrial dysfunction has been suggested to be the key factor in the development and progression of cardiac hypertrophy. The onset of mitochondrial dysfunction and the mechanisms underlying the development of cardiac hypertrophy (CH) are incompletely understood. The present study is based on the use of multiple bioinformatics analyses for the organization and analysis of scRNA‐seq and microarray datasets from a transverse aortic constriction (TAC) model to examine the potential role of mitochondrial dysfunction in the pathophysiology of CH. The results showed that NADH:ubiquinone oxidoreductase core subunit S1‐ (Ndufs1‐) dependent mitochondrial dysfunction plays a key role in pressure overload‐induced CH. Furthermore, in vivo animal studies using a TAC mouse model of CH showed that Ndufs1 expression was significantly downregulated in hypertrophic heart tissue compared to that in normal controls. In an in vitro model of angiotensin II‐ (Ang II‐) induced cardiomyocyte hypertrophy, Ang II treatment significantly downregulated the expression of Ndufs1 in cardiomyocytes. In vitro mechanistic studies showed that Ndufs1 knockdown induced CH; decreased the mitochondrial DNA content, mitochondrial membrane potential (MMP), and mitochondrial mass; and increased the production of mitochondrial reactive oxygen species (ROS) in cardiomyocytes. On the other hand, Ang II treatment upregulated the expression levels of atrial natriuretic peptide, brain natriuretic peptide, and myosin heavy chain beta; decreased the mitochondrial DNA content, MMP, and mitochondrial mass; and increased mitochondrial ROS production in cardiomyocytes. The Ang II‐mediated effects were significantly attenuated by overexpression of Ndufs1 in rat cardiomyocytes. In conclusion, our results demonstrate downregulation of Ndufs1 in hypertrophic heart tissue, and the results of mechanistic studies suggest that Ndufs1 deficiency may cause mitochondrial dysfunction in cardiomyocytes, which may be associated with the development and progression of CH.
Effects of autoclaving (Pleurotus osteratus) spent mushroom substrate water extract on the minerals, elicitors, cassava yield and the management of African cassava mosaic virus
Authors: E. Okere S. , E. Ataga A.
Published: March 2021

Farmers all over the world spend millions of dollars to partially control plant diseases that attack their crops using agrochemicals that pollute the environment. Plant diseases reduces crop yield, quality and shelf life. Enhancing the inherent ability of plants to resist diseases using elicitors and minerals is one of the neglected, sustainable, low cost and environmental friendly approaches to ensure the continued supply of food and fiber.Therefore the aim of this paper is to evaluate the composition of the elicitors and minerals in autoclaved and unautoclaved water extract of Pleurotus osteratus spent mushroom substrate and the effects of its application on the management of African cassava mosaic virus (ACMV), growth and yield of cassava. The treatments for this investigation comprised of Pleurotus osteratus water extract spent mushroom substrate (POWESMS), Pleurotus osteratus autoclaved spent mushroom substrate (POAWESMS) and untreated cassava plants as control. The mineral compositions and the elicitors in the treatments were evaluated using standard procedures. The data generated were subjected to analysis of variance (ANOVA) at (p=0.05). The results obtained from this investigation revealed significant differences in the values of resistant elicitors and minerals. Significant differences were also recorded for the growth, yield parameters and disease severity evaluated at 4 weeks interval. The results showed that unautoclaved water extract performed significantly better than the autoclaved in reducing ACMD severity which did not translate to higher crop yield.
Manifestations and Outcome of Cardiac Sarcoidosis and Idiopathic Giant Cell Myocarditis by 25‐Year Nationwide Cohorts
Authors: Nordenswan Hanna‐Kaisa , Lehtonen Jukka , Ekström Kaj , Räisänen‐Sokolowski Anne , Mäyränpää Mikko I. , Vihinen Tapani , Miettinen Heikki , Kaikkonen Kari , Haataja Petri , Kerola Tuomas , Rissanen Tuomas T. , Kokkonen Jorma , Alatalo Aleksi , Pietilä‐Effati Päivi , Utriainen Seppo , Kupari Markku
Published: March 2021

Background

Cardiac sarcoidosis (CS) and giant cell myocarditis (GCM) share many histopathologic and clinical features. Whether they are parts of a one‐disease continuum has been discussed.

Methods and Results

We compared medical record data of 351 CS and 28 GCM cases diagnosed in Finland since the late 1980s and followed until February 2018 for a composite end point of cardiac death, aborted sudden death, and heart transplantation. Heart failure was the presenting manifestation in 50% versus 15% (
P
<0.001), and high‐grade atrioventricular block in 21% versus 43% (
P
=0.044), of GCM and CS, respectively. At presentation, left ventricular ejection fraction was ≤50% in 81% of cases of GCM versus in 48% of CS (
P
=0.004). The median (interquartile range) of plasma NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) was 5273 (2782–11309) ng/L on admission in GCM versus 859 (290–1950) ng/L in CS (
P
<0.001), and cardiac troponin T exceeded 50 ng/L in 17 of 19 cases of GCM versus in 48 of 239 cases of CS (
P
<0.001). The 5‐year estimate of event‐free survival was 77% (95% CI, 72%–82%) in CS versus 27% (95% CI, 10%–45%) in GCM (
P
<0.001). By Cox regression analysis, GCM predicted cardiac events with a hazard ratio of 5.16 (95% CI, 2.82–9.45), which, however, decreased to 1.58 (95% CI, 0.71–3.52) after inclusion of markers of myocardial injury and dysfunction in the model.

Conclusions

GCM differs from CS in presenting with more extensive myocardial injury and having worse long‐term outcome. Yet the key determinant of prognosis appears to be the extent of myocardial injury rather than the histopathologic diagnosis.
Prevalence and outcome of young stroke patients with middle cerebral artery stenosis
Authors: Xu Wenjuan , Zhang Xiaoyu , Chen Huan , Zhao Zhangning , Zhu Meijia
Published: March 2021

Background

Etiologies of acute ischemic stroke in young adults are heterogeneous. Middle cerebral artery (MCA) stenosis is a common finding in Asians which may be an important cause of stroke in young adults. However, studies of stroke in young Asian populations are rare. Our study was to investigate the prevalence and outcome of young stroke patients with MCA stenosis in Chinese populations.

Methods

Young patients with MCA territory infarction between January 2013 and September 2018 were retrospectively recruited. Subjects were defined as stenosis group (MCA stenosis ≥50%) and no-stenosis group (MCA stenosis<50% or no stenosis) by their MCA stenosis. For patients in stenosis group, they were categorized as uni-MCA stenosis subgroup and multiple stenosis subgroup. Demographic data, risk factors, imaging feature and complications were compared between groups. Prevalence of MCA stenosis and risk factor score (score ≥ 2 or 3) in different age groups were investigated. Modified Rankin Scale (mRS) was used for evaluating functional outcome at discharge (unfavorable outcome: 3–6). Binary logistic regression was performed to determine independent risk factors of unfavorable outcome.

Results

Two hundred forty-nine young stroke patients were included in our study and 110 (44.2%) patients were defined as stenosis group. 55 (50%) patients were categorized as uni-MCA stenosis subgroup and 55 (50%) were multiple stenosis subgroup. The most common traditional vascular risk factors included hypertension, hyperlipemia, smoking, hyperhomocysteinemia and alcohol consumption. Prevalence of risk factor score ≥ 2 or 3 increased with age, but not incidence of MCA stenosis. By TOAST classification, the most common etiologies were large-artery atherosclerosis (41.0%) and small vessel disease (33.7%). Compared with no-stenosis group, patients in stenosis group were more likely to have large territorial infarct, develop complications and have unfavorable outcome. No significant difference was found between patients in uni-MCA stenosis and multiple stenosis subgroups except history of stroke/TIA, risk factor score ≥ 3 and silent infarct. By logistic regression, hypertension (OR = 3.561; 95%CI, 1.494 to 8.492;p = 0.004), NIHSS scores at admission (OR = 1.438; 95%CI, 1.276 to 1.620;p = 0,000) and infarct size (p = 0.015) independently predicted unfavorable outcome.

Conclusions

Forty-four point two percent young Chinese adults with MCA territory infarction had MCA stenosis. Prevalence of MCA stenosis did not increase with age. Patients with MCA stenosis had worse clinical outcome, however, only hypertension, NIHSS scores at admission and infarct size were independent predictors.
The effect of nutrition and reproductive health education of pregnant women in Indonesia using quasi experimental study
Authors: Permatasari Tria Astika Endah , Rizqiya Fauza , Kusumaningati Walliyana , Suryaalamsah Inne Indraaryani , Hermiwahyoeni Zahrofa
Published: March 2021

Background

Almost one-third of children under 5 years old in Indonesia suffer from stunting. Stunting can be prevented optimally during pregnancy as the initial phase of the first 1000 days of life. This study aims to determine the effect of nutrition and reproductive health education of pregnant women in Bogor Regency, Indonesia.

Methods

A quasi-experimental study was conducted among 194 pregnant women from August to November 2019. The pregnant women were randomly selected from four different villages in Bogor Regency. The intervention group (n = 97) received 2 h of nutrition and reproductive health education in small groups (four or five mothers per group) every 2 weeks for 3 consecutive months. This interactive education was given by facilitators using techniques such as lectures, role-playing, simulation, and games. The control group (n = 97) received regular health care services. A structured questionnaire was applied to collect data consisting of maternal characteristics, nutritional and reproductive health knowledge, attitudes, and practices in the intervention and control groups. Data were analysed using t-test and chi-square analysis.

Results

Pregnant women in the intervention group indicated a significant increase in knowledge, attitudes, and practices regarding nutrition and reproductive health after receiving education. The pre-test and post-test mean scores in the intervention group were 55.1 and 83.1 for overall knowledge, 40.2 and 49.0 for attitudes, and 36.2 and 40.2 for practices, respectively. In the control group, there was no significant difference between the pre-test and post-test mean scores for these three variables. There was a significant difference (P < 0.001) in the post-test mean between the intervention group and the control group, but the difference was not significant (P > 0.05) in the pre-test.

Conclusion

Providing nutrition and reproductive health education through small groups with interactive methods improves the knowledge, attitudes, and practices of pregnant women. This intervention has the potential to be replicated and developed for large-scale implementation by optimising collaboration between government, non-governmental organizations, and maternal and child health service providers.
MERIT: a mentor reflection instrument for identifying the personal interpretative framework
Authors: Loosveld Lianne M. , Van Gerven Pascal W. M. , Driessen Erik W. , Vanassche Eline , Artino Anthony R.
Published: March 2021

Background

Essential to the professional development of mentors is making explicit and critically challenging the knowledge and beliefs underpinning their mentoring practice. This paper reports on the development of a survey instrument called MERIT, MEntor Reflection InstrumenT, which was designed to support mentors’ systematic reflection on the how, what and why of their practice.

Methods

In 2019, a twenty-item survey instrument was developed and piloted. Initial validation data (N = 228) were collected by distributing the survey through the authors’ network. An exploratory factor analysis (EFA) was conducted and internal consistency reliability coefficients were calculated.

Results

The Principal Axis EFA with Direct Oblimin rotation (Delta = 0) resulted in four factors: 1) supporting personal development, 2) modelling professional development, 3) fostering autonomy, and 4) monitoring performance. The four factors explained 43% of the total variance of item scores. The Cronbach’s alphas for the subscale scores were between .42 and .75.

Conclusions

The MERIT can help mentors reflect on their beliefs and professional knowhow. These reflections can serve as input for the faculty development initiatives mentors undertake, which may ultimately improve their knowledge and skills as a mentor.
Best approximations of the ϕ-Hadamard fractional Volterra integro-differential equation by matrix valued fuzzy control functions
Authors: Rezaei Aderyani Safoura , Saadati Reza
Published: March 2021

In this article, first, we present an example of fuzzy normed space by means of the Mittag-Leffler function. Next, we extend the concept of fuzzy normed space to matrix valued fuzzy normed space and also we introduce a class of matrix valued fuzzy control functions to stabilize a nonlinearϕ-Hadamard fractional Volterra integro-differential equation. In this sense, we investigate the Ulam–Hyers–Rassias stability for this kind of fractional equations in matrix valued fuzzy Banach space. Finally, as an application, we investigate the Ulam–Hyers–Rassias stability using matrix valued fuzzy control function obtained through the Mittag-Leffler function.
The prevalence of depression symptoms among infertile women: a systematic review and meta-analysis
Authors: Kiani Zahra , Simbar Masoumeh , Hajian Sepideh , Zayeri Farid
Published: March 2021

Background

Infertile women’s mental health problems, including depression, are key fertility health issues that affect infertile women more severely than infertile men. Depression may threaten the health of individuals and reduce the quality of their lives. Considering the role and impact of depression on responses to infertility treatments, a systematic review and meta-analysis were conducted to investigate the prevalence of depression symptoms among infertile women.

Methods

International databases (PubMed, Cochrane Library, Web of Sciences, Scopus, Embase, and PsycINFO), national databases (SID and Magiran), and Google Scholar were searched by two independent reviewers for articles published from 2000 to April 5, 2020. The search procedure was performed in both Persian and English using keywords such as “depression,” “disorders,” “infertility,” “prevalence,” and “epidemiology.” The articles were evaluated in terms of their titles, abstracts, and full texts. The reviewers evaluated the quality of the articles using the Newcastle–Ottawa Scale, after which they analyzed the findings using STATA version 14. The I2 and Egger’s tests were performed to examine heterogeneity and publication bias, respectively.

Results

Thirty-two articles were subjected to the meta-analysis, and a random effects model was used in the examination given the heterogeneity of the articles. The samples in the reviewed studies encompassed a total of 9679 infertile women. The lowest and highest pooled prevalence rates were 21.01% (95% confidence interval [CI]: 15.61–34.42), as determined using the Hospital Anxiety and Depression Scale, and 52.21% (95% CI: 43.51–60.91), as ascertained using the Beck Depression Inventory, respectively. The pooled prevalence values of depression among infertile women were 44.32% (95% CI: 35.65–52.99) in low- and middle-income countries and 28.03% (95% CI: 19.61–36.44) in high-income countries.

Conclusion

The prevalence of depression among infertile women was higher than that among the general population of a given country. Especially in low- and middle-income countries, appropriate measures, planning, and policy that target the negative effects of depression on infertile women’s lives should be established to reduce related problems.
The Nonlinear Linkage Between Earnings Homogamy and Earnings Inequality Among Married Couples
Authors: Shen Yifan
Published: March 2021

More married couples today consist of two high-earning or two low-earning partners (i.e., earnings homogamy), which leads to greater earnings inequality in married-couple families. Surprisingly few studies have examined this relationship by earnings level, leaving open the question of whether the increase in earnings homogamy at each level of earnings contributes equally to between-couple earnings inequality. I address this question using data on urban China during 1988–2013. Changes in earnings homogamy account for 6% to 11% of the increase in between-couple inequality, but importantly, decomposition reveals that 57% to 68% of the overall impact is driven by the growing earnings homogamy among the top 20% of husbands and their wives. I reach the same finding by replicating the analyses using data from the United States. Two explanations account for this finding: (1) earnings homogamy has increased more among high earners; and (2) all else being equal, increases among high earners are mechanically more influential in shaping the level of between-couple inequality. These findings have important theoretical and policy implications.
Interactions among brand credibility, brand affect and brand behavioural intentions in professional sports teams: the moderation role of brand affect and live stadium attendance
Authors: Yağız Kadir
Published: March 2021

The purpose of this study was to investigate the effect of brand credibility and brand affect on behavioural intentions of professional sports team consumers toward their teams, and also investigating the moderating role of their brand affect level, live attendance frequency in stadium and gender on this relationship. Results showed that brand credibility and brand affect had a significant and positive effect on behavioural intentions. Also, the importance sports consumers attached to brand credibility of a team in respect to their behavioural intentions differed at their varying level of brand affect, live attendance frequency and gender. Through this study it was presented to sports managers about the mechanisms through which brand credibility exerts its effect on consumers' behavioural intentions across the varying level of brand affect, live attendance frequency and gender which would guide in their strategic brand management implementations.
Konvergensi media pada perkembangan radio komersial di Yogyakarta (studi kasus pada radio Geronimo FM dan radio Swaragama FM)
Authors: Annisa Fitriana Nur
Published: March 2021

Perkembangan teknologi memungkinkan media konvensional khususnya media penyiaran televisi dan radio yang bersifat satu waktu dapat berubah bersifat multi-channel yang juga merupakan bagian dari sifat konvergensi media. Konvergensi media merupakan salah satu perkembangan media massa yang banyak melibatkan faktor teknologi dalam prosesnya. Kehadiran internet membuat media konvensional menerapkan konsep konvergensi media yang memunculkan tren seperti munculnya e-paper, e-book, radio streaming, dan media sosial. Dalam penelitian ini, penulis memfokuskan pada bagaimana radio sebagai media tradisional dapat terus berkembang dengan menerapkan konvergensi media. Garis besar tulisan ini membahas radio yang mulai berkolaborasi dengan media baru dan pengaruhnya terhadap perkembangan Radio Geronimo FM dan Radio Swaragama FM di Yogyakarta. Penelitian ini menggunakan metode studi kasus dengan teknik pengumpulan data berupa wawancara mendalam, observasi, dan dokumentasi dengan pihak internal Radio Geronimo FM dan Radio Swaragama FM. Hasil dari penelitian ini adalah kedua radio sudah sangat memaksimalkan konvergensi media dengan baik yang dibuktikan dengan perluasan jangkauan pendengar, memperbesar kesempatan pengiklan dengan media sosial, dan perluasan ekonomi mengacu konglomerasi ekonomi.
KORELASI PERSEPSI TENTANG EFEK SAMPING KEMOTERAPI DENGAN KUALITAS HIDUP PASIEN KANKER PAYUDARA
Authors: Sari Shanti Lesmana , Indra Rani Lisa , Lestari Raja Fitriana
Published: March 2021

Chemotherapy treatments undergone by breast cancer patient’s have several side effect. From the side effects that, each patient perceives the side effects that will interfere with their daily lives which in turn affect the quality of life. This research was made for showing the correlation of chemotherapy side effect with the quality of life of breast cancer patient’s in Arifin Achmad Hospital in Riau Province. The research was one of quantitative correlation research with cross-section method that had been done to 63 respondents in Arifin Achmad Hospital in Riau Province by using consecutive sampling technique bye used was questionnaire. The test used unpaired t-test. This research result was gotten if Pvalue=0.216 (Pvalue=0.05), which mean is no correlation between chemotherapy side effect perspective and quality of life of breast cancer patient’s. Based on the result, we hope Arifin Achmad Hospital in Riau Province develop more health service to the community to increase positive judgement from chemotherapy treatment and quality of life of breast cancer patient’s.
HUBUNGAN MEKANISME KOPING DENGAN TINGKAT KECEMASAN PASIEN KANKER YANG MENJALANI KEMOTERAPI
Authors: Andinata Aryati , Marni Erna , Erianti Susi
Published: March 2021

Chemotherapy refers to a procedure treatment by using drugs that can kill cancer cells. The chemotherapy can cause anxiety of patient because they feel frightened physically and mentally. Therefore, the proper coping mechanism should be done to face this problem. This research aims to know about the correlation between coping mechanism and the anxiety level of the patient with cancer who was doing chemotherapy at RSUD Arifin Achmad Riau Province. This is quantitative research with descriptive correlation design and cross-sectional approach. The instrument used in this research is questionnaire. There is 96 respondent involved as the sample for this research. All of the respondents is the patient with cancer who was doing chemotherapy at RSUD Arifin Achmad Riau Province. The author used an accidental sampling method. The analysis style used in this research is the single variable with frequency distribution and two variable with the Kolmogorov-Smirnov statistic test. The result of this research shows that there is no significant effect of coping mechanism towards the anxiety level with p-value = 1,00 (p ≥ 0,05). The author gives a suggestion to RSUD Arifin Achmad Riau Province to increase the quality of coping mechanism to their patient.
Kemitraan berbasis masjid: pemutaran compact disc “sehat jiwa raga” untuk sosialisasi perilaku hidup bersih dan sehat
Authors: Hartiningsih Dini , Agustin Helfi
Published: March 2021

The Yogyakarta City Government launched an innovation in health promotion at mosques, named the "healthy inside and outside"  in 2015. This program is a partnership with the mosque keeper to promote clean and healthy living habits. No studies have yet evaluated the extent of the success of the program. This study aims to see the effectiveness of the program in changing people's healthy behaviour. This type of research is an analytic survey with a cross-sectional study approach.  The research location is in the working area of the Umbulharjo Community Health Center. The population is 4608 families. The number of samples is 108 people who live around the mosque. The inclusion criteria is housewives because they have a lot of time at home, so there are more opportunities to be exposed to Compact Disc (CD) in mosques than other people who work outside the home. The exclusion criteria were people who were unwilling and deaf. The sampling technique is a probability proportionate to size, namely by taking the sample referring to mosques that play CDs and those that do not play with 2: 1 ratio. The control variables are age and level of education. Data were collected through a questionnaire and analyzed by Mann Whitney-test. The results showed a difference in the community's mean knowledge and attitudes around the mosque playing  (69.44) and not playing the health promotion CD (60.14). The Mann Whitney-test results obtained a p-value of 0.00, which means there is an effect of CD health promotion playing on the level of public knowledge about PHBS. The playing CD  health promotion at mosques in Umbulharjo District, Yogyakarta, has benefited from increasing housewives' knowledge about healthy and clean behaviour.
Cerita bergambar kuliner seru bersama sahabat buah: media alternatif edukasi pemilihan jajanan sehat
Authors: Dwi Jatmika Septian Emma , Laila Farikhah Nur , Mufidatusholihah Mufidatusholihah , Andinie Ravika , MWH Fitri Rekyan
Published: March 2021

Children often have problems with snacks. They need health education to be able to choose healthy foods to meet optimal nutritional intake. This study aims to see the effect of using picture book media on increasing knowledge about healthy culinary tourism at Public Elementary School Gedongkiwo Yogyakarta. This type of study is quasi-experimental research. The survey designed is One Group Pretest Post Test Design. The research participants were 25 grade 2 elementary school students. The data analysis technique used the Paired Sample T-Test statistical test. The result obtained is that picture books do not affect knowledge about healthy culinary tourism (p-value 0.770> 0.05). A total of 9 students experienced a decrease in their level, seven students experienced an increase, and nine students did not experience a reduction or increase in knowledge. It is possible because the method used is combining lectures with visual story media during class. The conditions are different if students read pictorial stories themselves during leisure time. The next researcher will be able to study using a more simple method, for example, while having group discussions so that there is a two-way exchange of information.
Practices in research, surveillance and control of neglected tropical diseases by One Health approaches: A survey targeting scientists from French-speaking countries
Authors: Molia Sophie , Saillard Juliette , Dellagi Koussai , Cliquet Florence , Bart Jean-Mathieu , Rotureau Brice , Giraudoux Patrick , Jannin Jean , Debré Patrice , Solano Philippe
Published: March 2021

One health (OH) approaches have increasingly been used in the last decade in the fight against zoonotic neglected tropical diseases (NTDs). However, descriptions of such collaborations between the human, animal and environmental health sectors are still limited for French-speaking tropical countries. The objective of the current survey was to explore the diversity of OH experiences applied to research, surveillance and control of NTDs by scientists from French-speaking countries, and discuss their constraints and benefits. Six zoonotic NTDs were targeted: echinococcoses, trypanosomiases, leishmaniases, rabies, Taenia solium cysticercosis and leptospiroses. Invitations to fill in an online questionnaire were sent to members of francophone networks on NTDs and other tropical diseases. Results from the questionnaire were discussed during an international workshop in October 2019. The vast majority (98%) of the 171 respondents considered OH approaches relevant although only 64% had implemented them. Among respondents with OH experience, 58% had encountered difficulties mainly related to a lack of knowledge, interest and support for OH approaches by funding agencies, policy-makers, communities and researchers. Silos between disciplines and health sectors were still strong at both scientific and operational levels. Benefits were reported by 94% of respondents with OH experience, including increased intellectual stimulation, stronger collaborations, higher impact and cost-efficiency of interventions. Recommendations for OH uptake included advocacy, capacity-building, dedicated funding, and higher communities’ involvement. Improved research coordination by NTD networks, production of combined human-animal health NTD impact indicators, and transversal research projects on diagnostic and reservoirs were also considered essential.
Epidemiology of human leptospirosis in urban and rural areas of Brazil, 2000–2015
Authors: Galan Deise I. , Roess Amira A. , Pereira Simone Valéria Costa , Schneider Maria Cristina
Published: March 2021

Background

Leptospirosis is one of the most widespread zoonosis in the world and Brazil has the highest number of cases in Latin America. Transmission occurs mainly through exposure to water and soil contaminated by the urine of infected animals. The goals of this study are to describe the geographic distribution, demographic characteristics and exposure factors of urban and rural cases of leptospirosis, and identify spatial clusters in urban and rural areas of Brazil.

Methods/results

A retrospective epidemiological study was carried out using 16 years (2000–2015) of surveillance data from the Brazilian Ministry of Health. Cases were described by age, sex and race, and exposure factors were characterized in urban and rural areas. A spatial autocorrelation analysis was conducted using local Moran’s I to identify urban and rural clusters of disease. On average 3,810 leptospirosis cases were reported annually with higher numbers in urban areas. National urban and rural incidence rates were the same (1.9 cases/100,000 population), however, regional differences were observed. Urban incidence rates were higher in the North and Northeast regions, while rural incidence rates were higher in the Southeast and South. The main exposure factor reported in urban and rural areas was exposure to places with signs of rodents, followed by flood in urban areas and agriculture and animal farming in rural areas. Clusters of leptospirosis were identified in densely populated urban areas of the North, Southeast and South regions, while rural clusters were concentrated in of the Southern region with large agriculture and animal farming practices.

Conclusions

This study highlights that leptospirosis is an important public health problem in both urban and rural areas of Brazil. The results provide decision-makers with detailed information about where disease incidence is high and can be used in the development of prevention and control strategies for priority areas and risk groups.
Design of facile technology for the efficient removal of hydroxypropyl guar gum from fracturing fluid
Authors: Xu Shiliang , Cui Mengke , Chen Renjie , Qiu Qiaoqing , Xie Jiacai , Fan Yuxin , Dai Xiaohu , Dong Bin
Published: March 2021

With the increasing demand for energy, fracturing technology is widely used in oilfield operations over the last decades. Typically, fracturing fluids contain various additives such as cross linkers, thickeners and proppants, and so forth, which makes it possess the properties of considerably complicated components and difficult processing procedure. There are still some difficult points needing to be explored and resolved in the hydroxypropyl guar gum (HPG) removal process, e.g., high viscosity and removal of macromolecular organic compounds. Our works provided a facile and economical HPG removal technology for fracturing fluids by designing a series of processes including gel-breaking, coagulation and precipitation according to the diffusion double layer theory. After this treatment process, the fracturing fluid can meet the requirements of reinjection, and the whole process was environment friendly without secondary pollution characteristics. In this work, the fracturing fluid were characterized by scanning electron microscopy (SEM), Energy dispersive X-ray (EDX), X-ray diffraction (XRD) and Fourier transformed infrared (FTIR) spectroscopy technologies, etc. Further, the micro-stabilization and destabilization mechanisms of HPG in fracturing fluid were carefully investigated. This study maybe opens up new perspective for HPG removal technologies, exhibiting a low cost and strong applicability in both fundamental research and practical applications.
The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1
Authors: He Wencan , Azzi-Martin Lamia , Velasco Valérie , Lehours Philippe , Dubus Pierre , Djavaheri-Mergny Mojgan , Ménard Armelle
Published: March 2021

Humans are frequently exposed to bacterial genotoxins of the gut microbiota, such as colibactin and cytolethal distending toxin (CDT). In the present study, whole genome microarray-based identification of differentially expressed genes was performedin vitroon HT29 intestinal cells while following the ectopic expression of the active CdtB subunit ofHelicobacter hepaticusCDT. Microarray data showed a CdtB-dependent upregulation of transcripts involved in positive regulation of autophagy concomitant with the downregulation of transcripts involved in negative regulation of autophagy. CdtB promotes the activation of autophagy in intestinal and hepatic cell lines. Experiments with cells lacking autophagy related genes, ATG5 and ATG7 infected with CDT- and colibactin-producing bacteria revealed that autophagy protects cells against the genotoxin-induced apoptotic cell death. Autophagy induction could also be associated with nucleoplasmic reticulum (NR) formation following DNA damage induced by these bacterial genotoxins. In addition, both genotoxins promote the accumulation of the autophagic receptor P62/SQSTM1 aggregates, which colocalized with foci concentrating the RNA binding protein UNR/CSDE1. Some of these aggregates were deeply invaginated in NR in distended nuclei together or in the vicinity of UNR-rich foci. Interestingly, micronuclei-like structures and some vesicles containing chromatin and γH2AX foci were found surrounded with P62/SQSTM1 and/or the autophagosome marker LC3. This study suggests that autophagy and P62/SQSTM1 regulate the abundance of micronuclei-like structures and are involved in cell survival following the DNA damage induced by CDT and colibactin. Similar effects were observed in response to DNA damaging chemotherapeutic agents, offering new insights into the context of resistance of cancer cells to therapies inducing DNA damage.
A Critical Evaluation of the Estonian Cyber Incident
Authors: Buresh Donald L.
Published: March 2021

This paper evaluates the effect of the Estonian cyber incident on Estonia, Russia, the United States, the European Union, and the North Atlantic Treaty Organization, also known as NATO. The paper employs the Valeriano and Maness criteria for evaluating a cyber incident critically. The article asks how did the Estonian cyber incident come to pass, what were the foreign policy and international relationship effects, what was the impact on Estonia, and how did Estonia react to the attack. The essay concludes that the Estonian cyber incident was a catalyst, prompting the nations listed herein to address the effects of cyber-attacks, and then search for acceptable solutions.
Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
Authors: Silvestre Ramona A. , Almería Lafuente Alejandro , Jiménez-Mendiguchía Lucía , García-Cano Ana , Romero López Rubén , García-Izquierdo Belén , Pardo de Santayana Cristina , Iglesias Pedro , Diez Juan J. , Arribas Gómez Ignacio , Bernabeu-Andreu Francisco A.
Published: March 2021

Objectives

Graves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard TRACE-immunofluorescence; (ii) to determine the diagnostic validity of the three methods.

Methods

A retrospective study in 194 patients with a TRAb determination request. TRAb were determined by immunofluorescence (Kryptor, ThermoFisher) and chemiluminescence (Immulite, Siemens and Maglumi, Snibe). Clinical validation: medical records were reviewed and categorized according to thyroid function. Statistical analysis: Differences in quantitative variables were assessed by intraclass correlation coefficient, Bland–Altman plot, and mean differences (mD). Qualitative variables were dichotomized by cut-off points; Kappa coefficient was calculated. Correlations were evaluated by Pearson’s coefficient and Passing-Bablok regression analysis. The diagnostic validity of the three methods was investigated.

Results

Kryptor-Immulite: mD: 1.2 (95%CI: −16 to >18). Passing-Bablok: Constant error (95%CI: −0.8349 to −0.5987). Proportional error (95%CI: 0.7862–1.0387). ICC: 0.86 (95%CI: 0.82–0.89). Kappa coefficient: 0.68 (95%CI 0.59–0.78). Kryptor-Maglumi: mD: −0.3 (95%CI: −12 to >12). Passing-Bablok: Constant error (95%CI: −0.7701 to >0.1621. Proportional error (95%CI: 0.8571 to 1.3179. ICC: 0.93 (95%CI: 0.89–0.97). Kappa coefficient: 0.53 (95%CI: 0.32–0.74). Diagnosis of Graves’ disease was confirmed in 113 patients (Kryptorf showed better specificity and positive predictive value, whereas Immulite demonstrated better sensitivity and negative predictive value).

Conclusions

The three methods have a good diagnostic performance for Graves’ disease, with superimposable results on Bland–Altman plot. Interchangeability was not confirmed on the regression and agreement analysis, with the presence of biases.