bluuebunny/crossref_metadata_2025 huggingface dataset:
Anxiolytic Effects, Antioxidant and Anti-inflammatory Activities of the Methanol Extract of Jatropha tanjorensis Leaf
Authors: Aiwonegbe Anthony E. , Omoruyi Uwaila , Ogbeide Osahon K. , Imoukhuede Blessing O. , Gabrielsson Benjamin O.
Published: October 2022

The methanol leaf extract of Jatropha tanjorensis was analyzed for its bioactive components, in-vitro antioxidant, antidepressant, anxiolytic and anti-inflammatory activities using established methods. The phytochemicals detected were saponins, tannins, terpenoids, phenolic compounds, alkaloids, flavonoids and eugenols. The total phenolic content (TPC) was 36.48 mgGAE/g, while the total flavonoid content (TFC) was 145.92 mgQE/g of the extract. 1, 1-diphenyl-2-picrylhydrazyl radical scavenging activity gave an IC50 of 185.02 and 5.15 µg/mL for the extract and ascorbic acid (standard), respectively. The 50% lethal dose (LD50) was greater than 5000 mg/kg, while graded doses of 50, 100 and 200 mg/kg of the plant extract relieved depression in mice to 93.3, 100 and 80.8%, respectively when compared with 10 mg/kg amitriptyline (positive control). A significant anxiety reduction, exemplified by a decrease in the frequency of head dip, was observed for animals administered with the plant extract compared with untreated control (p < 0.05). The reduction of formalin-induced paw edema was significant (p < 0.01) at 50 mg/kg of the plant extract, when compared with the control. The methanol extract of J. tanjorensis leaf is therefore a potential source of plant medicine with remarkable pharmacological activities.

Keywords:    Jatropha tanjorensis; anxiolytic; antidepressant; anti-inflammatory; antioxidant; phytochemicals
Bogusław Przywora, Normatywny model przedsądowej nieodpłatnej pomocy prawnej w Polsce, Wydawnictwo C.H. Beck, Warszawa 2019, ss. 434
Authors: Zaleśny Jacek
Published: October 2022

Bogusław Przywora, Normative Model of Unpaid Pre-Litigation Legal Aid in Poland, Warsaw 2019, pp. 434

In the reviewed monograph, Bogusław Przywora constructs a normative model of unpaid pre-litigation legal aid in Poland. It is an important issue (both theoretically and practically) from the point of view of the realization of human rights and freedoms. It is also essential for the legal culture and legal awareness of participants in legal relations. The author poses an important research problem: how is the normative model of unpaid pre-litigation legal aid in the Constitution of the Republic of Poland, international and EU law? As part of the main research problem posed in this way, the author poses detailed research questions. Answering them required a number of considerations: theoretical-legal, comparative-law, legislative, and legal acts. The applied multifaceted approach to the issue allowed the Author to explain it and propose really important directions for the desired changes. They are intended to improve the legal solutions already used in Poland for unpaid pre-litigation legal aid. This monograph is not only interesting but also inspiring. The proposals contained in it are characterized by high application values.
Development of written L2 French: a longitudinal study of learners in the Norwegian school context
Authors: Woldsnes Anne-Kathrine
Published: October 2022

This paper presents a longitudinal multiple case study that focused on the development of the written interlanguage of four learners over their three years of learning French as a second language (L2) in upper secondary school in Norway. The development of macro-level syntactic complexity and the development of micro-level measures of accuracy in morphosyntactic features specific to written French were examined. In order to trace development of syntactic complexity, we used two well-established measures in the SLA literature: T-unit length and the number of dependent clauses per T-unit (Wolfe-Quintero et al., 1998; Verspoor et al., 2017), whereas the morphosyntactic features representing the basis for our analysis of accuracy were gender and number in the noun phrase in French. The results illustrated that the written French of all four learners clearly became more syntactically complex over the three years of the study. As regards the development at the morphosyntactic level, progress was less straight forward in the individual learners, and the developmental tendencies varied according to the nature of the features studied.
STUDIES ON THE GROWTH AND PRODUCTION PERFORMANCE OFROHU (LABEO ROHITA) AT DIFFERENT STOCKING DENSITIES ININTENSIVE AQUACULTURE SYSTEMS USING FLOATING FEED
Authors: Arifuzzaman Md. , Rahman Md. Hashibur , Haque Mohammad Mahfujul , Islam Md. Nasirul
Published: October 2022

The study was conducted to assess the growth and production of rohu (Labeo rohita) in intensive aquaculture system in relation to feed conversion ratio (FCR). To assess the weight gain, SGR and FCR, the experiment was performed in six concrete tanks under a shed located on the southern th rd corner of Faculty of Fisheries, BAU for 100 days from 26 June to 3 September, 2018. Rohu fry was released at the rate of 4 fry per tank equivalent to the stocking density of 160 fishes/decimal for treatment 1 T and at the rate of 8 fry per tank equivalent to the stocking density of 320 fishes/decimal for treatment 1 2 T . Floating feeds were used for feeding the fish in both treatments. There were three (3) replications 2 for each treatment. During experimental period, feed was given at the rate of 12%, 8%, and 4% of the body weight in first 30 days, second 30 days and final 40 days, respectively. The weight gains of fish were 42.89±1.509 g and 23.49±4.039 g for T and T respectively. The mean percent weight gain of rohu 1 2, was higher in T (588.12±0.00) than T (319.29±0.00). Feed conversion ratio (FCR) in T and T were 1 2 1 2 2.21 and 2.99, respectively. The specific growth rate (SGR) of rohu in T and T were 1.92±0.275 and 1 2 1.43±0.108, respectively. The SGR for T was higher and FCR was lower in production cycle than T . 1 2 The total production was obtained 201.56±0.00 g in T and 248.08±0.00 g in T , respectively with 100% 1 2 survival rate in both the treatments.
CIRCUMSPOROZOITE PROTEIN (CSP) GENETIC DIVERSITY IN INDIAN PLASMODIUM VIVAX
Authors: Siwal Nisha
Published: October 2022

India is one of the Plasmodium vivax endemic countries and contributes the highest number of malaria cases worldwide. P. vivax CSP (PvCSP) is one of the most extensively studied antigen and is considered to be a leading malaria vaccine candidate gene. VK210 and VK247 are the two variants described in the central repeat region of P. vivax CSP gene. VK210 (98%) is found to be more prevalent as compared to VK247 (2%) in Indian context. It was noticed that different geographical regions show diversity in nucleotides as well as in haplotype with respect to PvCSP gene of Indian isolates. As natural selection always plays an important role in shaping genomic diversity in Indian P. vivax, the central repeat region of PvCSP gene of all the five-populations found to be under strong purifying selection. In this region, a number of synonymous mutations were found to be higher in number as compared to non-synonymous mutation, which clearly indicated that PvCSP gene is involved in invasion of hepatocytes in the host body and the parasite can't afford non-synonymous changes in this region. The present study helps us to understand the nature of P. vivax population in India, and also that might be helpful in planning the development of PvCSP-based vaccine in India.
extremismo ideológico e o apolitismo
Authors: Alencar Alves Pereira Thiago
Published: October 2022

O presente artigo científico tem como objetivo geral estudar a relação existente atualmente entre sociedade e representantes do povo, uma vez que se observa apatia social com a classe política, o que denota certa depressão democrática e risco ao Estado Constitucional de Direito, como idealizado na contemporaneidade. Para melhor organizar o raciocínio, o objetivo específico foi centrado em estudar qual o papel do povo no Estado, a função dos representantes do poder e o movimento democrático contemporâneo. A metodologia utilizada é a indutiva, utilizando-se de conceitos pré-existentes de Estado, Poder e democracia. A conclusão, portanto, é que existe o desinteresse social pela política é fruto do distanciamento dos representantes do povo da ética e da moral, tendo em vista que os discursos e promessas políticas não se convalidam quando chegam ao Poder.

 

Palavras-chave: Democracia. Ética. Poder. Política. Povo.
Direitos reprodutivos
Authors: Dias Antunes Amanda
Published: October 2022

O presente artigo se propõe a abordar, incialmente e de forma mais ampla, a judicialização da política na atualidade. Para tanto, faz-se essencial contextualizar tais fenômenos em um cenário de instabilidade constitucional e democrática que se percebe em escala global. Especificamente, pretende-se investigar possibilidades de desenvolvimento da pauta dos direitos das mulheres, em especial os direitos reprodutivos, pela via judicial, sopesando tal caminho com os tradicionais revezes políticos e sociais inatos ao sistema democrático. Nesse ponto, além da análise do caso brasileiro, aborda-se o debate sobre backlash desencadeado pelo julgamento histórico Roe v. Wade. O que se objetiva, assim, de forma específica é explorar caminhos de acesso a direitos fundamentais de forma estratégica e compromissada com a democracia como sistema de debate e inclusão em que diversos personagens devem se entender como parte de um amplo encadeamento político.
Role of Governance, Trade, and Tourism in Foreign Direct Investment in Pakistan
Authors: Fatima Areeba , Safdar Noreen , Afzal Naureen
Published: October 2022

The Primal objective of this research is to reveal the role of governance, tourism, and trade in the stimulation of FDI inflows in Pakistan. These forces have been integrated for empirical methodology after a detailed examination of past studies. The study took data set for selected variables from World Development Indicators (WDI) and World governance indicators (WGI) for the past two decades (2000-2021). Except for governance, tourism, and trade, this research incorporates macroeconomic stability and financial development as the stimulators of FDI inflows in Pakistan. In statistical data estimation, after using the ADF test, the ARDL technique is applied based on the variable's cointegration order. Both short and long-run estimates of ARDL confirmed the statistical significance of all studied variables that are governance (GOVEF), tourism (LTRSM), trade (TD), gross savings (GS), and broad money (BM). Bound test and CUSUM disclosed that there is long-run cointegration and the examined model is statistically significant and stable. Overall findings disclosed that GOVEF and trade are positively correlated, while LTRSM confirmed a negative association with FDI inflows for the case of Pakistan.
N-acetylcysteine Alleviates Depression through Up-regulation of Synaptophysin, Inhibition of Reactivity Astrocytes, and Anhedonia in the Forced Swim Test Animal Model
Authors:   Department of Anatomy, Faculty of Basic Medical Sciences, Edo State University, Uzairue, Nigeria, Memudu Adejoke
Published: October 2022

Depression is a mental disorder of global concern, with chronic psychological stress being one of the underlying predisposing factors. This study evaluated the role of the antioxidant, N-acetylcysteine (NAC), as an antidepressant using the forced swim test (FST) animal model. Thirty adult male Wistar rats (250 g average weight) were randomly grouped into six (n=5): Control (1 ml/day of normal saline); FST model; NAC (200 mg/kg/day); Fluoxetine (20 mg/kg/day); FST model treated with NAC (200 mg/kg/day), and FST model treated with Fluoxetine (20 mg/kg/day). All the treatments were orally. The FST, sucrose-preference test (SPT), and brain weights were assessed, and data analysed. The histo-architecture of the prefrontal cortex (PFC), as well as the immunohistochemistry of astrocytes and synaptophysin were also assessed. Findings showed that NAC prevented FST-induced depressive behaviour demonstrated by increased SPT and mobility time. NAC also prevented the FST-induced decreased brain weights and neuronal loss, reduced proliferation of reactive astrocytes, and diminished synaptophysin immunoreactivity in the PFC similar to that of fluoxetine, a standard antidepressant drug. NAC exhibited its neuroprotective mechanism via inhibiting the proliferation of reactive astrocytes, and protecting neurons and synapses from oxidative tissue damage induced by FST, hence, an increase in synaptophysin activity that culminated in increased neural activity, increased SPT, and reduced immobility time.
Analysis of the Effect of Knowledge on the Implementation of Management Functions of Public Health Centers in Bengkulu Province
Authors:   Widyaiswara Ahli Madya UPTD Pelatihan Kesehatan Bengkulu, Yandrizal Yandrizal
Published: October 2022

Background: Community Health Center carrying out the authority task to implement the stages of management functions. The application of management requires good knowledge to be able to implement planning, mobilizing implementation, monitoring, and controlling assessments optimally. Materials/Methods: The research was conducted using a quantitative method with a cross-sectional approach. The research population is the Head in charge of health efforts at Public Health Center throughout Bengkulu Province. The data was collected using a questionnaire and analyzed using the Chi-Square Test with the help of the SPSS 22 application. Result: The research affects planning knowledge, Organizing Actuating, monitoring, and linearly controlling the assessment. Knowledge of supervision control appraisal has less effect on the implementation of management functions simultaneously. Conclusion: Applying knowledge management in health services will improve service quality for targeted and sustainable services. Knowledge management in health services can be improved to help improve the quality, efficiency, and effectiveness of services. Mobilizing the implementation of health programs must pay attention to available resources to optimize their respective roles and functions. Resource based mobilization is useful in adding perspective to knowledge mobilization in healthcare organization
The Validity of the Power of Attorney Based on the Parties’ Forgive Documents
Authors:   1Student of Master in Notary Study Program of Universitas Sebelas Maret, Rizqillah Intan Novia Putri , Suryono Arief ,   Lecturer in Faculty of Law Universitas Sebelas Maret, Ciptorukmi N Anjar Sri ,   Lecturer in Faculty of Law Universitas Sebelas Maret
Published: October 2022

: Notaries as officials have the authority to make authentic deeds as well as other authorities as regulated in Law Number 2 of 2014 concerning Notary Position Regulations. Notaries are responsible for what is witnessed, seen, and also carried out by the notary himself as a public official who carries out his position. This research is a normative research with a descriptive analytical approach to legislation. The purpose of this research is to examine and further analyze the validity of the notarial deed made based on forged documents by the appearers. The results of the study indicate that the making of a Power of Attorney based on a forged document is null and void and the Notary is not responsible if the appearers provide false documents because the notary is not obliged to investigate materially about everything presented by the appearers.
Driving Factors in the Implementation of Digital Transformation Strategy
Authors:   Autonomous University Of Guerrero Mexico, Torrez JuliÃ¡n Miranda
Published: October 2022

The objective was to identify the factors that drive the implementation of the digital transformation strategy. It was based on the theories of organization, strategic management, and digital technologies. The method, a qualitative analysis and systematic review of recently published and high impact documents was carried out. As a result, a model was proposed that relates the factors and the strategy through propositions at four levels of analysis: individual, organization, ecosystems, and geopolitics. Originally, the knowledge of digital transformation is expanded by associating it with the theoretical perspectives of strategy, organizations, and management.
Pilates . Efectos en la función física y sus limitaciones. Revisión sistemática y metaanálisis (Pilates . Effects on physical function and its limitations. Systematic review and metaanalysis)
Authors: López Mesa Mario Manuel , Rodríguez González Eva María
Published: October 2022

El objetivo principal de esta revisión es realizar un análisis, síntesis e integración de los resultados de los efectos de los ejercicios del método de Pilates en la función física, las limitaciones por problemas de salud física (rol físico) y el dolor corporal, evaluados con la escala de nivel de calidad de vida SF-36. Se efectuó búsqueda en las bases de datos de Pubmeb, PEDRo, Scopus, Scielo, Google Scholar y Semantic Scholar, identificando un total 170 artículos, después de realizar los procesos de selección, elegibilidad e inclusión, se seleccionaron diez artículos. En relación a la función física, se observan cambios estadísticamente significativos en siete de los diez estudios y el tamaño promedio de los efectos pueden ser considerados medianos (Cohen´s d= 0,71 [IC del 95%: 0,45 a 0,98]) y con relación a las limitaciones por problemas de salud física y al dolor corporal, se observan cambios estadísticamente significativos en cinco de los diez estudios, el tamaño promedio de los efectos pueden ser considerados medianos (limitaciones por problemas de salud física Cohen´s d= 0,78 [IC del 95%: 0,51 a 1,05]; dolor corporal Cohen´s d= 0,59 [IC del 95%: 0,30 a 0,89]). Con base en estos resultados, los ejercicios de pilates son una forma eficiente de terapia física y mejoran moderadamente la calidad de vida relacionada con la función física y sus limitaciones
Palabras claves
Pilates, Cuestionario de Calidad de Vida SF-36, calidad de vida, función física, Rol físico, dolor corporal.
Abstract. The main objective of this review is to carry out an analysis, synthesis and integration of the results of the effects of the Pilates method exercises on physical function, limitations due to physical health problems (physical role) and body pain, evaluated with the SF-36 quality of life level scale. A search was carried out in the Pubmeb, PEDRo, Scopus, Scielo, Google Scholar and Semantic Scholar databases, identifying a total of 170 articles. After carrying out the selection, eligibility, and inclusion processes, ten articles were selected. In relation to physical function, statistically significant changes are observed in seven of the ten studies and the average size of the effects can be considered medium (Cohen's d= 0.71 [95% CI: 0.45 to 0.98 ]) and in relation to limitations due to physical health problems and bodily pain, statistically significant changes are observed in five of the ten studies, the average size of the effects can be considered medium (limitations due to physical health problems Cohen's d = 0.78 [95% CI 0.51 to 1.05]; body pain Cohen's d = 0.59 [95% CI 0.30 to 0.89]). Based on these results, Pilates exercises are an efficient form of physical therapy and moderately improve quality of life related to physical function and its limitations.
Keywords. Pilates, Quality of Life Questionnaire SF-36, quality of life, physical function, physical role, body pain.
Assessing emotional, empathic and coping skills in Spanish undergraduates in Health Sciences and Social Sciences
Authors: Martínez-Lorca Manuela , Zabala-Baños Mª Carmen , Morales Calvo Sonia , Romo Roberto Aguado , Martínez-Lorca Alberto
Published: October 2022

Background: Higher education is considered to be one of the phases in the life cycle that produces psychological distress and academic pressure. The aim of the study was to assess to assess the emotional, empathic and coping skills of undergraduate students of Health Sciences and Social Sciences undergraduates using an explorative approach in a cross sectional study.
Methods: A sample of 693 first-to-fourth-year students enrolled in different degree courses. We used an “ad hoc” questionnaire, the Trait Meta-Mood Scale (TMMS-24), Trait Meta-Mood Scale (TMMS-24), The Interpersonal Reactivity Index (IRI) and Brief COPE.
Results: We found higher scores in capacity for empathy using the IRI, in emotional intelligence by TMMS-24 and a good coping style and adaptive strategies measured on the COPE, however, emotion regulation scores in DERS were medium. We found interesting relationships between female, first-year course, sport, anxiety and degree course in empathy, emotional intelligence, adaptative strategies and emotional regulation.
Conclusions: Preventive and train measures in emotional and psychosocial resources are needed in higher education to achieve the highest possible level of psycho- emotional well-being.
Keywords: emotional intelligence, empathy, coping skills, subjective well-being, students.
Physical fitness levels in students with and without training capacities – A comparative study in physical education classes
Authors: Martins Júlio , Honório Samuel , Cardoso João
Published: October 2022

Introduction: The practice of Physical Activities is a cultural habit and as such it must be acquired in childhood so that there is a greater probability of being continued throughout life. Physical Activities on a regular and duly regulated basis, even if they are at ages where this component is absolutely fundamental, not only for their motor development but for their socialization and creation of healthy lifestyles. Objective: The study aims to evaluate the levels of Physical Fitness of middle-school students, between students who practice Physical Education and those who, in addition to this, performed a training programme. Methods: Participated 32 students of both genders aged between 10 and 11 years old divided into two groups with the same number of students (16): the Training Group which, in addition to attending Physical Education classes, benefited from a training programme and the other group that only attended the physical education classes. The Fitnessgram battery tests was applied for flexibility, strength and aerobic capacity. Results: Through this study, it was presented that the use of a physical training programme, eight weeks before the final moment, allowed the training group to obtain significant differences, in the tests results, from the initial moment to the final moment in terms of physical fitness when compared with the group that only attended physical education classes. Conclusions: This study allows us to understand that the fact that the Training Group benefited from a Physical Skills Training, improved the performance levels of the students in this group at the final moment.
Key words: Physical Fitness, Fitnessgram, Physical Education, Training capacities.
Application of intervention strategies for behavior management in autism spectrum disorder in childhood and adolescence. a systematic review
Authors: Teresa Penagos Paola , Meneses Castaño Cyndi Yacira , Álvarez Toro Lina Johana
Published: October 2022

Introduction and objectives: autism spectrum disorder (ASD) is a neurodevelopmental disorder, which exhibits symptoms such as early-onset impairment of interaction and social communication, as well as repetitive and restricted sensory and motor behavior. This study aims to carry out a systematic review regarding the application of intervention strategies for behavior management in autism spectrum disorder in childhood and adolescence. Methods: A systematic search of Randomized Controlled Clinical Trials conducted between January 2016 and June 2021 found in PubMed, Scient direct y Scopus was performed. Keywords used were “Psychomotor, disorder, autism, behavior, intervention”. Results: 2 845 records were found, and, after further analysis, 45 articles were obtained for the final analysis, with a number of participants (n=3 439), age range: 8-17 years of age, confirmed diagnosis of autism spectrum disorder. As a result, we found The use of technological resources is associated with a significant reduction in clinical severity of ASD, functioning global assessment, and social manifestations of anxiety. Conclusions: the authors to conclude that there are several strategies used for behavior management in autism spectrum disorder, the use of technological tools stands as a promising option as they are highly beneficial and contribute to achieve behavioral therapeutic objectives.
Keywords: Psychomotor, disorder, autism, behavior, intervention.
Effects of Capital Structure on the Financial Performance of Listed Consumer Goods Firms in Nigeria (2011-2021)
Authors:   Department of Accounting, Ekiti State University, Ado-Ekiti, Nigeria, C. O Olaoye
Published: October 2022

The study investigated the effect of capital structure on the financial performance of listed consumer goods firms in Nigeria between 2011 and 2021. A sample of ten firms was purposively selected from the study’s population of twenty four consumer goods firms listed on the Nigerian Stock exchange. The study employed secondary source of data obtained from the financial statements of the selected firms and the data collected was analyzed using random effects model. Findings from the study showed that the coefficient of share capital is negative (−1.86262) and insignificant (p=0.7961>0.05) and the beta value of short-term debt is positive (5.08662) and insignificant (P=0.1596 >0.05). The coefficient of long-term debt is also positive (6.78568) and statistically significant (p=0.0298<0.05) and the beta value of retained earnings is positive (3.55649) and insignificant (p=0.2617>0.05) for the same firms in Nigeria. The study concluded that share capital has a negative and significant effect on the financial performance, while retained earnings, short-term debt and long-term debt have positive effects on the firms’ financial performance. The study recommended that the consumer goods firms in Nigeria should avoid financing their operations with share capital without taking remedial actions on it persistence negative effect on their performance and Nigerian governments should be formulating new industrial policies that will rebrand the local enterprises including consumer goods firms instead of insisting on their annual corporate tax increase.
Avance del proceso de evaluación de riesgo de extinción de los mamíferos en Colombia
Authors: Gómez-Valencia Bibiana , Baptiste Maria P. , Ramírez-Chaves Hector E. , Noguera-Urbano Elkin A. , Suarez-Castro Andres Felipe , Torres-Martínez María M. , Pantoja-Peña Gabriel , Lizcano Diego J.
Published: October 2022

La evaluación de riesgo de extinción de los mamíferos de Colombia se ha realizado heterogéneamente en los últimos 16 años. Sin embargo, las evaluaciones de los mamíferos de Colombia están desactualizadas. Por esta razón, se hace necesario renovar la evaluación del riesgo de extinción de los de mamíferos de Colombia. Este proceso se realiza de manera articulada y con el apoyo de expertos y entidades según los criterios de la Unión Internacional para la Conservación de la Naturaleza (IUCN). Esta labor ha servido además, para consolidar información de especies pobremente documentadas con información de colecciones biológicas o con fototrampeo. El proceso de evaluación terminará en 2022 con los esfuerzos de la Sociedad Colombiana de Mastozoología, el Instituto de Investigación de Recursos Biológicos Alexander von Humboldt, la Asociación Colombiana de Zoología y el apoyo de otras organizaciones.
Factors Influencing Persons with Disability Participation in Socioeconomic Development in Seme Sub-County, Kenya
Authors: Okoth Nancy , Wamalwa Fred
Published: October 2022

Purpose: The study examined the factors influencing persons with disability participation in socioeconomic development in Seme sub-county, Kenya. This study answered the research questions with regards to the education level, public infrastructure and cultural practices influence on the involvement of persons with disability on socio economic development in the Seme sub-county?

Methodology: The study was anchored on the margin and empowerment theories. Qualitative and research method was applied through a descriptive survey design. Questionnaires and interviews were the data collection instruments administered to 208 respondents. Quantitative data were analyzed using descriptive statistics.

Findings: The study established that low levels of education, lack of inclusive public infrastructure, and cultural influences/ stigmatization had a significant negative influence on persons with disability involvement in socioeconomic activities.

Unique Contribution to Theory, Practice and Policy: The study recommends that institutions supporting persons with disabilities and the Sub-county administration should invest in disabled supporting education, public infrastructure and perception changes in the community with regards to cultural barriers. provision of formal education and advocacy on the rights of persons with disability. Finally the study fills research gaps in marginalization and empowerment theories in education, infrastructure and culture and stigma towards persons with disabilities.
The Efficacy and Safety of Percutaneous Cystolithotripsy for Vesical Calculus in Children: A Single-Center Study
Authors: Khan Mohammad Kamran , Hassan Asiya , Hanif Mohammad , Alam Gohar , Ali Liaqat , Naveed Mohammad , Ullah Ihsan
Published: October 2022

Purpose: The study aimed to assess the outcome and safety of PCCL in the pediatric population coming with bladder stones in developing countries.

Methodology: Patients of pediatric age with vesical calculus were evaluated for PCCL. Department of Peads Urology Institute of Kidney Diseases Thirty participants were included in the single center study, with enrollment beginning in January 2000 and ending in August 2021. General anesthesia was used for the operation. Following a cystoscopy examination, a suprapubic puncture was performed, and the urethral tract was dilated to a maximum of 26 Fr. Pneumatic lithotripsy was used to break up the stone. A nephroscope was used to see where it was lodged so it could be removed. A percutaneous urethral catheter was inserted was taken out after 48 postoperative hours.

Findings: The patients' median age was 4.1 (1-10). Patients tended to be men. The typical size of a gem was 10.1 millimeters. The average operational time to successfully remove the stones was just 30 minutes. Hematuria, infection, and mild mucosal damage were the only serious complications seen during or after surgery, and all were treated conservatively. Ammonium acid urate comprised the bulk of the stones and the nucleus in 26 cases (86%). Percutaneous suprapubic lithotripsy is a tested and reliable method with a high success rate for treating bladder stones in children. The procedure is short and has few adverse effects.
A Comparative Performance Evaluation of IPv4/IPv6 Using Network Simulation and Virtualization Tools
Authors: Almutlaq W.M. , Elfadil N.
Published: October 2022

Internet users are expected to grow from 4.5 billion in 2020 to 5.3 billion by 2023. In terms of the population, this represents 66% of the global population. However, the growth of connected devices and internet users is going very fast. Not yet as the number of the internet of things (IoT) applications such as video surveillance, smart meters, and tracking and the machine to machine increased as well. The address space of the IPv4 cannot meet these requirements and this growth in the connected devices. According to that another IP address scheme designed to meet the requirements and the needs for the IoT & M2M and the growth of the number of internet users. This is the IPv6 which consist of 128 bit and can provide a huge number of addresses. The limitation of the addressing space was solved by the IPv6 but the problem arises in the migration from IPv4 to IPv6 as the migration cannot happen overnight so transition mechanisms developed to allow the communication between both IPv4 and IPv6 network. This paper aims to study the performance parameters such as the delay, the throughput, and the TCP establishment time which could be affected by the transition mechanism. The methodology that used in this project is using a network simulation tools such as GNS3 and virtual box to simulate the network scenarios and network performance check such as Wireshark and iperf3 tools to analyse the traffic. The results in this project show that if the delay is the main concern, then the tunneling machine will be the best choice, behind that when the TCP flow playing an important role for the network engineer then the tunneling machine will be the best option. However, the dual-stack method is considered the best in terms of throughput.
Role of ICT in Library Administration with its Impact
Authors: Pazare Anil Pudlik , Jain Sunita
Published: October 2022

The term "information" refers to any form of know-how, facts, or data. Information should be repackaged to make it more easily digestible for users. Knowledge is transformed into information through the act of "externalization," or the act of communicating it to others. Communication technologies are only useful if they allow users to access information quickly, cheaply, and reliably. The library at the university offers a wide variety of ICT-enabled services, such as online catalogue (OPAC), electronic resources (e-resources), and more. Research has been conducted to determine the effects of information and communication technology (ICT) on various sections of the CUSAT library by monitoring the operations of these areas, interviewing staff and patrons, and examining library databases. This paper serves as a presentation of the research findings.
The Effects of Structured Instrument-Playing for the Elderly in R esidential C are on t heir S ub jective Happiness and Depression
Authors:   Korean Association of Music Therapy and Psychological Rehabilitation, Park Jin-sol , Moon Soyoung
Published: October 2022

This study investigated the effects of structured instrument-playing on the improvement of subjective happiness and the reduction of depression of the elderly in residential care. The experimental group consisted of 10 elderly people from S residential care in city “J,” and the control group had 10 elderly people from C, S residential care in city “J.” Before implementing the structured instrument-playing, the subjects were pre-tested to obtain measures of their subjective happiness and depression levels.
For the experimental group, the experimental procedure was carried out for a total of 14 sessions, 50 minutes each, during the period of February 13 to March 31, 2017. After these sessions, post-tests were conducted to both groups to track any changes in the participants’ subjective happiness and depression levels. Following is the summary of the major findings: First, structured instrument-playing appeared to have a positive effect on improving the subjective happiness of elderly people in residential care. Also, the data also showed that structured instrument-playing had a positive effect on the participants’ inner happiness, external happiness, and self-control happiness. Second, structured instrument-playing also had a positive effect on reducing depression of elderly people in residential care. By proving that this study works, the findings of this study suggest that structured instrument-playing program can be effective for improving the elderly residents’ subjective happiness and depression. Also, the study suggests that structured instrument-playing can be applied to improve the effectiveness of programs for not only the elderly in residential care but also to nursing home elderly, frail and dementia elderly.
Comparison of Power flow Enhancement for varying loads using different Controllers
Authors: Agrawal Niharika , Ahmed Khan Faheem , Gowda Mamatha
Published: October 2022

The power demand is continuously increasing due to population growth and changes in lifestyle. Due to shortage of generation and transmission facilities it is desired to increase the existing transmission line power transfer capacity in order to meet the rising demand. Fixed capacitors(FC) and TCSC FACTS device are used to increase the power flow of the line .The advantage in TCSC is that it provides variable compensation instead of fixed compensation by FC. In the present work the comparison of power flow enhancement by fixed capacitors , single TCSC and two modules of TCSC are done for three cases . The three cases are load is suddenly increased and decreased, load is suddenly decreased and increased, load is increased and then further increased. Various Power quality issues like voltage sag ,voltage swell are discussed. The THD voltage and receiving end voltage with different controllers/devices are shown. The power flow is more with TCSC in the system than with FC. The power flow is further enhanced using two modules of TCSC in the system.
La inviolabilidad regia y sus límites en el ordenamiento jurídico español
Authors: Fernández Iriondo Jon
Published: October 2022

Este artículo aborda el posible conflicto entre la inviolabilidad regia y los principios que caracterizan a un Estado social y democrático de Derecho como el Reino de España, y tiene por objetivo explorar los límites de la inviolabilidad del Monarca tanto desde una perspectiva de interpretación de la legislación vigente como desde la propuesta de reforma. Se asume la hipótesis de que “inviolabilidad” no equivale a “impunidad” —o al menos no debería— en un Estado social y democrático de Derecho que propugna la igualdad y la justicia, entre otros, como valores superiores de su ordenamiento jurídico. Tras aclarar los conceptos de inviolabilidad, irresponsabilidad y refrendo, se aborda las diferentes posiciones doctrinales respecto a delimitación de esta prerrogativa regia en términos temporales, materiales y en relación al poder legislativo. Finalmente, se esboza una modesta propuesta de reforma.
La fallida justicia poética del Tribunal Constitucional en el amparo parlamentario sobre la designación de senadores autonómicos: comentario a la Sentencia 56/2022
Authors: Ortega Santiago Carlos
Published: October 2022

La Sentencia 56/2022 del Tribunal Constitucional resuelve un recurso de amparo con criterios que ponen en cuestión la atribución de los Parlamentos autonómicos para designar senadores, en favor de la facultad de los grupos parlamentarios para proponer los candidatos a esa designación. La decisión supone un paso más en la deconstrucción de la representación política tradicional y en la definición de una nueva articulada de manera casi exclusiva en los partidos políticos y los grupos parlamentarios.
The Arab world on the verge of the energy transition: Challenges, ambitions, and limits to growth
Authors: Filonik A. O. , Baturina V. N.
Published: October 2022

Nowadays the socio-economic and political agenda of almost all countries of the Arab East includes the issues of sustainable development and green energy. The natural conditions of the region and its vulnerability to natural disasters prioritize the issues of environmental security and transition to renewable energy sources. The research has two objectives. Firstly, the authors attempt to outline prospects for enhancing capacities in clean energy production and replacing traditional energy sources that emerged in recent years in the Arab countries. Secondly, the paper assesses challenges and limits for green practices dissemination, as well as their capabilities of providing environmental security for the countries in the region. The authors note that an alternative approach to power generation is gradually taking root in the region and, judging by the scale of major projects being implemented, it has good prospects, especially in the field of solar energy. At the same time, despite the advantages of such projects, they have serious economic and technological constraints including pricing issues, problems of energy storage and waste disposal. However, the authors emphasize that the main obstacle to a coherent and effective climate policy for the entire Arab East stems from strong disproportions in economic development of the regional actors. The article thoroughly examines the experience of the most advanced Arab countries in the areas of renewable energy — the United Arab Emirates and Saudi Arabia. The authors note that these countries actively experiment with all known renewable energy sources, including hydrogen-based, but at the same time, they are seeking to develop nuclear power. However, their ambitious projects do not reflect the real situation in the region as a whole, where most countries are extremely cautious in making risky, expensive decisions on energy and climate policy. They are not ready to unconditionally adopt Western approaches to ‘greening’ economy and take a wait-and-see attitude. This may explain certain inertia towards renewable energy sources that is shown by most countries of the Arab East.
Correction of the Mitochondrial NADH Oxidase Activity, Peroxidation and Phospholipid Metabolism by Haplogenin-7-Glucoside in Hypoxia and Ischemia
Authors: Umidakhon Yusupova , Erkin Botirov , Ulugbek Gayibov , Bahadir Niyazmetov , Karim Almatov
Published: October 2022

In this study, it was used haplogenin-7-glucoside flavonol (C16H12O8) isolated from the plant Haplophyllum perforatum. It was studied the effect of haplogenin-7-glycoside on NADH oxidase activity, peroxidation, and phospholipid metabolism in rat liver mitochondria under in vitro conditions. Incubation of mitochondria at 37 ℃ leads to disruption of the integrity of mitochondrial membranes, as a result, in cytochrome с desorption from the inner membrane into the intermembrane space, which leads to a decrease in the activity of rotenone-sensitive NADH oxidase and an increase in the activity of rotenone-insensitive NADH oxidase. Haplogenin-7-glucoside exhibits membrane stabilization by reducing these alterations. Under ischemia conditions, the effect of haplogenin-7-glucoside on the LPO process in mitochondria decreases LPO in mitochondria. Quantitative changes in phosphatidylserine in mitochondrial membranes under LPO conditions during incubation of mitochondria at 37 ℃ were observed to accelerate controlled (auto-oxidation) LPO over time (0 - 90 min). Peroxidation of phosphatidylserine in mitochondria when the addition of haplogenin-7-glucoside to the incubation medium at 30, 60 and 90 min, LPO was found to be reduced. The increasing amount of phosphatidylinositol has not happened depend on time. However, a slight increase was found under the influence of haplogenin-7-glucoside.

HIGHLIGHTS

Cytochrome c desorption from the inner membrane into the interstitial space leads to a decrease in the activity of rotenone-sensitive NADH-oxidase and an increase in the activity of non-rotenone-sensitive NADH-oxidase

Haplogenin-7-glycoside showed membrane-stabilizing properties by significantly reducing these changes; the addition of haplogenin-7-glucoside to mitochondria leads to a decrease for MDA, a decrease in the LPO process

At incubation of mitochondria at 37℃, the amount of phosphatidic acid and lysophosphatidic acid in mitochondria under LPO conditions was also found to be less than control under the influence of haplogenin-7-glucoside. Thus, haplogenin-7-glucoside reduces the rate of peroxidation of phospholipids in liver mitochondria and has a corrective effect

GRAPHICAL ABSTRACT
Koncepcja odporności systemów społeczno-ekologicznych wobec innych aktualnych koncepcji rozwoju oraz uwagi krytyczne
Authors: Masik Grzegorz
Published: October 2022

The aim of the article is to identify the concepts of development concerning the functioning of socio-ecological systems that share common elements with the concept of resilience. The second aim is to identify critical remarks relating to the concept of resilience, which are seldom raised by researchers and practitioners. The above goals were achieved on the basis of a query of mainly international literature relating to the concept of resilience of socio-ecological systems. The results of the research indicate that in the literature dealing with the issue of resilience, links with the concept of vulnerability and sustainable development are relatively often indicated. Critical comments relate to understanding resilience as an objective feature independent of the adopted axiology, understanding resilience in a purely positive context, and understanding resilience as the ability to withstand negative shocks rather than the ability to constantly adapt.
El trabajo por proyectos como una estrategia educativa para el fomento de la creatividad y la motivación del alumnado. Tres proyectos de creación artística en el ámbito de la formación inicial del profesorado
Authors: García Roldán Ángel
Published: October 2022

En el siguiente artículo se analizan tres experiencias docentes que en el ámbito de la educación artística dentro de la formación inicial del profesorado hacen uso de una metodología educativa basada en el trabajo colectivo por proyectos, estableciendo distintas dinámicas para el aprendizaje autónomo y colaborativo dentro del aula. Gracias al desarrollo de los distintos mapas creativos puestos en juego en estas experiencias se plantean nuevas formas de aprender y enseñar, obligando a reconsiderar la estructura tradicional educativa basada en la relación profesor-alumno, sus formas de interacción y las herramientas y procedimientos de evaluación para favorecer, además, una educación en competencias más acorde con los contextos y requerimientos sociales actuales.
La regeneración de los sentidos
Authors: Cano Rojas Guillermo
Published: October 2022

Presentación vol. 2.
Investigación y arte. La investigación y la difusión desde la experiencia estética
Authors: Díaz Bucero Jesús , Sánchez Pérez María Dolores
Published: October 2022

La investigación en Arte y la introducción de la creatividad en los trabajos científicos crea debates y conflictos que marcan el desarrollo de tesis doctorales e investigaciones. Debates que surgen de espacios intermedios entre el conocimiento lógico y emocional. Este trabajo se presenta bajo la forma de experiencia y recoge nuestro enfoque del conflicto y cómo hemos abordado la investigación dentro de él a través de la experiencia estética. Se muestra como el lugar donde crecer en la investigación desde Bellas Artes en un punto intermedio entre el sentimiento y la razón, en una conjunción de ambas y se utiliza la razón estética expuesta por Chantal Maillard como un tipo de conocimiento que permite estudiar el arte desde su experimentación. Estas líneas muestran la importancia otorgada a la experiencia estética en nuestro trabajos desde tres puntos diferentes, teniendo presentes que todos son consecuentes y dependientes de los otros: La comunicación desde la experiencia estética (donde se sitúan las capacidades comunicativas de toda obra de arte en función de las capacidades receptivas del espectador), la investigación desde la experiencia estética (donde se muestra cómo la emoción puede combinarse en la investigación científica gracias al conocimiento sensible) y la difusión científica desde la experiencia estética, que propone usar la forma básica de comunicar en arte dentro de la investigación: difundir a través de la creación.
Entrevista al profesor Román de la Calle. Investigar en los dominios de las Bellas Artes. (2ª Parte)
Authors: Martínez Barragán Carlos , Cerezuela Juan Antonio
Published: October 2022

Durante el mes de noviembre de 2012 el equipo editorial de la Revista Sonda pudo entrevistar a Román de la Calle -Alcoy (Alicante), 1942- Catedrático de Estética y Teoría del Arte de la Universitat de Valéncia-Estudi General, ensayista y crítico de arte, se ha dedicado profesionalmente a la docencia durante más de cuarenta años. Actualmente es el Presidente de la Real Academia de Bellas Artes de San Carlos. Las contribuciones del profesor Román en el campo de las humanidades y del arte, muy especialmente en Valencia, forman parte de la historia viva de la cultura y la creación en España. En esta segunda entrega el profesor Román hace hincapié en la necesidad ética de toda acción humana, en cómo ésta ética se convierte en uno de los valores inalienables de la obra de arte. Y también revisa las diferentes corrientes filosóficas con la que se ha generado la investigación en las artes desde el espacio universitario.