bluuebunny/crossref_metadata_2025 huggingface dataset:
patrimônio cultural no Plano Diretor de São Paulo
Authors: Cavalcanti Pessoa Mariana , Muniz Claudia , Kimie da Silva Nito Mariana , Brito do Nascimento Flávia
Published: October 2023

O presente artigo discute as políticas de patrimônio cultural no município de São Paulo nas suas relações com o planejamento urbano. O texto recupera a trajetória histórica dos planos diretores na Capital paulista, problematizando os conceitos e instrumentos para a salvaguarda do patrimônio. Do Plano Diretor de Desenvolvimento Integrado do Município (PDDI) de 1971 até a atual revisão do Plano Diretor Estratégico de 2014,  discutimos criticamente as potencialidades, os limites e os impasses que foram sendo impostos à efetiva participação das políticas de planejamento urbano no campo do patrimônio, no seu sentido alargado.
Subsídios para a revisão do Plano Diretor Estratégico do Município de São Paulo de 2014
Authors: Nobre Eduardo
Published: October 2023

A Constituição Federal definiu que o plano diretor é o instrumento básico da política de desenvolvimento e de expansão urbana, definindo os parâmetros do cumprimento da função social da propriedade e da cidade, sendo que o Estatuto da Cidade instituiu que ele deve ser revisto pelo menos a cada dez anos. O município de São Paulo instituiu seu primeiro Plano Diretor Estratégico seguindoessas as diretrizes em 2002, que foi revisto pela lei no 16.050/2014 previsto para um prazo de quinze anos. Em 2021 a Secretaria Municipal de Urbanismo e Licenciamento (Smul) iniciou o processo de revisão intermediária do plano. O presente trabalho busca contribuir para as discussões desta revisão trazendo resultados de pesquisa que contou com financiamento do Edital Universal do CNPq e do Projeto Regular da Fapesp. A primeira seção faz algumas considerações sobre os objetivos e as inovações implantadas pelo plano, a segunda analisa sua implementação, considerando os impactos sobre o mercado imobiliário, a captura da valorização imobiliária e sua redistribuição através das obras públicas e o atendimento dessas aos objetivos do plano, considerando a gestões municipais envolvidas, para concluir sobre a evolução de implementação do plano.
Encontros Plurais
Authors: Whitaker João
Published: October 2023

Trata-se de uma entrevista com o arquiteto e urbanista João Whitaker, diretor da Faculdade de Arquitetura e Urbanismo da Universidade de São Paulo, sobre a revisão do Plano Diretor Estratégico da Cidade de São Paulo, realizada no dia 23 de maio de 2023, no programa Encontros Plurais, promovido pela Escola de Gestão e Contas Públicas do TCMSP.
importância dos Tribunais de Contas para o processo de convergência da contabilidade aos padrões internacionais
Authors: Souza Gustavo Felipe Ripper Chalréo Tupinambá de , Carvalho Júnior Jorge Pinto de
Published: October 2023

Considerando o atual cenário brasileiro de busca por informações financeiras dotadas dos atributos de fidedignidade e tempestividade, o setor público passa por um momento de desafios na adaptação da contabi­lidade por meio do processo de convergência dos procedimentos contábeis às normas inter­nacionais. O presente estudo visou analisar a importância dos Tribunais de Contas brasilei­ros, como órgãos públicos responsáveis pela fiscalização e controle dos gastos públicos, nes­se contexto de padronização às Normas Inter­nacionais de Contabilidade Aplicadas ao Setor Público (IPSAS). Para tanto, é fundamental que os Tribunais de Contas participem ativamente desse processo para verificar o atendimento das exigências das novas normas, com o objetivo de assegurar maior adequação das demonstra­ções contábeis dos entes públicos aliado a uma maior transparência dos dados contábeis.
Lei Maria da Penha
Authors: Fernandes Angélica
Published: October 2023

O presente artigo se propõe a analisar os processos de institucionalização do cumprimento da Lei Maria da Penha, Lei 11.340/2006, no município de São Paulo e o papel do Controle Externo. É importante ressaltar que a Lei Maria da Penha regula­menta o direito da mulher vítima de violên­cia familiar e doméstica à assistência social, à saúde e à segurança pública. Seu arcabouço jurídico contém diversas ações afirmativas de caráter preventivo, assistencial e pedagógico, como também enuncia diretrizes para o cum­primento de políticas públicas através de ações sistêmicas de responsabilidade de cada ente fe­derativo. Os conteúdos do artigo são produto da reflexão de diversas autoras acerca do tema, dos resultados alcançados na implantação das políticas públicas e das contribuições do Con­trole Externo em diferentes dimensões. Ini­cialmente apresento os pressupostos teóricos que orientam a análise, e se detém em alguns conceitos estruturantes que explicam a neces­sidade do conjunto de ações propostas pela Lei 11.340/2006. Neste contexto, é mister desta­car como esse tema adquire relevo nos proces­sos sócio-políticos dinâmicos. Outro elemento abordado é o papel do investimento de recursos públicos para efetivação das iniciativas e servi­ços para combater a violência contra as mulhe­res previstos na Lei Maria da Penha através do acompanhamento da execução orçamentária. E neste contexto, como o Controle Externo pode atuar de forma preventiva e colaborativa na efe­tivação de direitos e no enfrentamento das as­simetrias denotadas na relação entre mulher e homem presente na sociedade e, em particular, na cidade de São Paulo.
Políticas de proteção à criança vítima de violência sexual. E o abusador? Merece atenção?
Authors: Foyen Simone Simone
Published: October 2023

Este trabalho tem por objetivo apresentar um panorama atual sobre a violência sexual contra a criança no âmbito do­méstico, assim como demonstrar a forma como a criança é tratada enquanto sujeito de direitos na atualidade. O tema é de bastante relevância, pois revela que tais condutas são praticadas na clandestinidade, em geral por pessoas do con­vívio dessa criança, com as quais preservam la­ços de afeto e carinho. Por este motivo, a análise dos meios pelos quais tais informações chegam ao sistema processual traça o cenário necessário para a compreensão destes fenômenos. Algumas iniciativas vêm sendo tomadas para minimizar o abalo emocional suportado pelas crianças e al­gumas ações do Poder Público sinalizam para a atenção a ser dispensada ao abusador como meio de romper o ciclo da violência sexual contra crianças no âmbito doméstico.
relevância dos Tribunais de Contas na consolidação do Estado democrático e de direito
Authors: Lima Daniel Alves Dias Caetano de , Meyer-Pflug Samantha Ribeiro
Published: October 2023

O presente artigo tem por escopo demonstrar a relevância e a essencialidade dos Tribunais de Contas, em todos os âmbitos da Federação, para a manutenção do Estado Demo­crático de Direito, principalmente após a promul­gação da Constituição Federal de 1988, analisando, desta forma, suas principais atribuições constitu­cionais, em especial, o controle das contas públicas e o auxílio ao Poder Legislativo no controle exter­no da Administração Pública. Ademais, mostrar-se-á, que tais Cortes de Contas são Instituições sui generis, uma vez que não pertencem e nem estão subordinadas a nenhum dos três Poderes do Es­tado, ocupando, portanto, um lugar peculiar em nosso sistema político-organizacional. Além disso, restará demonstrado que os Tribunais de Contas são fundamentais para a transparência dos atos pú­blicos e para a probidade administrativa, temas que são de suma importância no cenário atual, tendo em vista a crise política, econômica, ética e moral em que nos encontramos.
Organização do Sistema Único de Saúde (SUS): características fundamentais
Authors: Martins Manoel Henrique , Costa André Galindo da , Tonelo Daniel
Published: October 2023

0 Sistema Único de Saúde (SUS) brasileiro está dentre os mais universais e complexos sistemas de oferta de serviços e ações públicas de saúde do mundo. Este artigo tem o objetivo de descrever algumas caracte­rísticas importantes de organização do SUS, bem como aspectos relacionados à sua forma­ção histórica. Para o desenvolvimento dessa pesquisa foi realizada uma investigação biblio­gráfica, uma análise das normas e leis relacio­nadas ao SUS.
Controle Externo no Estado Democrático de Direito
Authors: Nogueira Fábio Túlio Filgueiras
Published: October 2023

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Papel da Câmara Municipal no Exercício do Controle Externo
Authors: Tuma Eduardo
Published: October 2023

O presente artigo tem por finalidade trazer ao leitor a importância do exercício do controle externo pela Câmara Municipal com o auxílio do Tribunal de Contas, como forma de garantir a correta utilização dos recursos públicos, a fim de que o Estado cumpra sua missão de solucionar os problemas da população, em observância ao princípio da primazia do interesse público.
Novos Tempos, Novos Caminhos
Authors: Cruz Dilson Ferreira da
Published: October 2023

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O Desafio da Educação 4.0
Authors: Nalini José Renato
Published: October 2023

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Vigilância governamental e a pandemia da Covid-19
Authors: Rolim Sofia Bordin
Published: October 2023

O presente artigo se propõe a examinar o uso de aplicativos de rastreamento de contatos durante a pandemia da Covid-19, em um contexto de vigilância governamental e autoritarismo digital crescentes. Através de uma perspectiva de proteção de dados, consideramos atributos chaves desses aplicativos, como sua arquitetura de sistema e gerenciamento de dados, examinando as principais implicações para privacidade. Exploramos brevemente alguns dos métodos de vigilância empregados ao redor do mundo e refletimos sobre suas implicações para as liberdades individuais e a democracia. Por fim, nós examinamos os resultados de uma revisão sistemática sobre a eficácia do rastreamento de contato automatizado para a prevenção da propagação do novo coronavírus.
São Paulo City Hall and the Covid-19 Pandemic
Authors: Bellamy Marian Salles Gomes , Santos Ricardo Ferreira , Di Pietro Eduardo Emílio Lang , Aly Vitor Levy Castex
Published: October 2023

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Government Surveillance Amid the Covid-19 Pandemic
Authors: Rolim Sofia Bordin
Published: October 2023

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Jurimetria e o Tribunal de Contas do Município de São Paulo
Authors: Garcia Gilson Piqueras , Lima Clara Bonfim Carvalho , Mota Eliezer Galdino da , Paula Karoline Dias Sales de , Souza Wilson de
Published: October 2023

Este trabalho tem o objetivo de descrever como se distribuem as variáveis dos processos de acompanhamento de licitações e contratos no Tribunal de Contas do Município de São Paulo (TCMSP). A pesquisa é quantitativa e o instrumento de análise de dados é a Jurimetria, que é a estatística aplicada ao Direito. O estudo é, portanto, descritivo. Este trabalho se justifica na medida em que é necessário conhecer quantitativamente a aplicação concreta da lei pelos Tribunais de Contas. Para tanto foi realizado levantamento dos julgamentos proferidos pelo mencionado Tribunal, através de pesquisa documental e os dados foram coletados na seção de jurisprudência do sítio eletrônico do TCMSP. Com base nos dados colhidos, pode-se verificar as distribuições das variáveis e duração dos processos de acompanhamento de licitações e contratos do TCMSP.
Planejamento Estratégico e Tribunais De Contas
Authors: Garcia Gilson Piqueras , Mosquetti Filho Cláudio , Braz Eli Moura , Sado Júlio Shizuo , Oliveira Thiago De
Published: October 2023

Assim como na iniciativa privada, o planejamento estratégico nas organizações públicas tem tensionado requisitos de Governança Corporativa (GC). O objetivo principal desta pesquisa foi identificar na conformação textual dos Planos Estratégicos (PLEs) dos Tribunais de Contas (TCs) nacionais, se estão explícitas a mentalidade de risco e a comunicação com as partes relacionadas como fruto de um Pensamento Estratégico (PTE) enraizado, impregnado e institucionalizado na Cultura Organizacional (CO), em detrimento de uma concepção de ferramentas prescritivas descoladas e isoladas do processo de Planejamento Estratégico (PE).Tratou- -se de uma pesquisa documental com finalidade exploratória, a qual utilizou métodos qualitativos de análise. Os resultados apontam que a maioria das abordagens sobre os mecanismos de GC ficaram na superfície e carregaram abstrações quanto à linguagem escrita e textual dos PLEs dos TCs nacionais. Além de repetições de termos técnicos de caráter instrumental e prescritivo, a ausência de elementos centrais confirma que há muito a se construir.
Urban Pandemic
Authors: Holston James
Published: October 2023

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Auditoria operacional na área da educação sob a ótica da eficiência
Authors: Mury Luiz Gilberto Monclaro
Published: October 2023

Este artigo visa apresentar um caso prático de auditoria operacional na área de educação a partir de análise comparativa entre a eficiência de escolas públicas do ensino fundamental em cinco municípios do Rio Grande do Sul, selecionados por meio da técnica de clusterização. Com base na metodologia Análise Envoltória de Dados, e usando as seguintes variáveis de entrada: gasto por aluno, número de alunos por computador/ tablet, número de alunos por professor e nível socioeconômico dos estudantes, e, como variável de saída, o Índice de Desenvolvimento da Educação Básica - Ideb 2019, objetivou-se medir o nível de eficiência das escolas desses municípios. A pesquisa conduzida identificou que do universo amostral de 21 escolas com dados disponíveis, apenas 4 alcançaram 100% de eficiência.
Os indicadores da pobreza no Brasil e a formulação de políticas públicas para o seu enfrentamento.
Authors: Saldanha Freitas Xavier de Souza Lorraine
Published: October 2023

O presente artigo tem como campo de estudo predominante as políticas públicas, na medida em que serão abordados os mecanismos básicos de identificação de problemas, a exemplo dos indicadores sociais, responsáveis por fornecer à sociedade e aos formuladores de políticas públicas dados quantitativos e qualitativos sobre a pobreza absoluta e a segurança alimentar em nosso país. A partir de uma pesquisa bibliográfica e documental, objetiva-se desenvolver a ideia de que as políticas públicas podem ser o meio adequado para o combate da pobreza no nosso país, dada sua capacidade de equacionar, ainda que minimamente, diretrizes de atuações governamentais voltadas ao desenvolvimento econômico e social. A partir da análise de gráficos contendo dados sobre a pobreza no Brasil, concluiremos que o conhecimento efetivo da realidade social pode ser capaz de conferir inteligibilidade ao problema da pobreza no país, incutindo nos governantes o conhecimento objetivo da realidade social a ser transformada. O resultado da conjugação destes critérios de análise é revestir de propósito e racionalidade o processo pré-decisório de formulação das políticas públicas, o que pode impactar diretamente a busca pela igualdade socioeconômica no Brasil e na América Latina.
Ansatser til en agential realistisk tænkning om læring
Authors: Plauborg Helle
Published: October 2023

Denne artikel udforsker, hvad man kan forstå ved læring med udgangspunkt i agential rea- listisk tænkning. En agential realistisk tænkning om læring gør en dyd ud af at udvise sensitivitet overfor den kompleksitet, læring som fænomen er karakteriseret ved. Læring er derfor en dynamisk og emergerende stør- relse, der er kendetegnet ved hele tiden at være i processer af at blive til, ligesom det også er kendetegnende for agential realistisk tænkning om læring, at spektret af kompo- nenter, der tillægges handlekraft i relation til læring, udvides markant. I artiklen fokuseres på materiel-diskursivitet, spatialitet og tem- poralitet. Derudover gentænkes begreber som tilegnelse og transfer, og der argumenteres med udgangspunkt i et observationsnotat for, at intra-aktivitet og “spring” er karakteristiske egenskaber ved læring. I en agential realistisk tænkning om læring er begrebet re-konfigura- tioner et omdrejningspunkt og med det brydes en tendens til at forstå læring som enten mere af det samme eller radikal forandring i form af “tiører der falder”. For skønt læreproces- ser, der ikke genkendes som “aha-oplevelser”, ikke gør meget væsen af sig, er det sådan, de forekommer flest.
Forestillinger om lykke
Authors: Storm Ida , From Ditte-Marie
Published: October 2023

Denne artikel undersøger forestillinger om lykke i moderskabet. I Danmark screenes ny- bagte mødre for depression to måneder efter fødslen. Hvis de scorer lavere end cut-off værdien for depression, men tilstrækkeligt højt til at indikere mistrivsel, så udløser det i flere kommuner tilbud om støttegrupper for mødre med efterfødselsreaktioner. Artiklen er baseret på analyser af seks kvalitative interview med mødre, der alle har deltaget i sådanne støttegrupper. De præsenterede analyser fremstiller mødrenes forventninger til det normale moderskab som karakteriseres ved lykke, sundhed og kontrol – egenskaber som mødrene idealiserer og efterstræber. Mødrenes fortællinger disku- teres i forhold til normen om det lykkelige mo- derskab og de afvigerpositioner, som normen samtidig udstikker.

Analyserne er teoretisk inspireret af kulturforsker Sara Ahmeds lykkeforskning. De er formet af en kulturelt betinget forestilling om, at lykke i dag konstrueres og betragtes som den vellykkede selvstyrings effekt og belønning. Fra dette perspektiv belyser artiklen de ikke-lykkelige mødres selvbebrejdelser, ek- sempelvis i form af skyld og skam over deres mistrivsel.

Denne mangel på trivsel analyseres gennem Mitchell Deans perspektiv på refleksiv styring og Erving Goffmans teorier om illegitime identiteter og front stage performance.

Artiklen udleder subjektpositioner som er tilgængelige for de kvinder, der oplever lykken som helt eller delvist fraværende i deres moderskab, og undersøger hvordan disse kvin- der positionerer sig for at tilpasse sig kulturelt betingede forventninger om moderlykke. Analyserne belyser, hvordan normen om det lykkelige moderskab afføder afvigerpositioner for de ikke-lykkelige mødre. Disse mødre frygter eksklusion fra de normale mødres fællesskab – et fællesskab, der associeres med samfundets mere velstillede lag. En afvigelse fra normen om det lykkelige moderskab forbinder sig så- ledes også med frygten for social devaluering.

Derfor har mødrene tendens til at skjule deres mistrivsel for omverdenen, enten gennem social isolation eller skuespil, ved at spille rollen som lykkelig mor i hverdagslivets sociale møder.

Som et overordnet resultat præsenterer denne artikel et nyt styringsperspektiv: performance of conduct – som et bidrag til de eksisterende analyser af selvstyring i vestlige samfund. Mødrene skjuler deres afvigelse ved at udføre selvstyringens skuespil for at overbevise omverdenen om deres normalitet og værd som mødre. Denne lykke-performance kan vanskeliggøre muligheden for at opdage og tilbyde støtte til de ikke-lykkelige mødre, hvis de kæmper med mistrivsel, selvbebrejdelse og skam i det skjulte. Samtidig forhindrer disse lykke-performances en mere omfattende udfordring af det lykkelige moderskab som norm.
ЗЕМЉА У ПОКРЕТУ: ДРУШТВЕНО-КУЛТУРОЛОШКИ ПРЕГЛЕД ИСТОРИЈЕ МИГРАЦИЈА БОСНЕ И ХЕРЦЕГОВИНЕ
Authors: Леро Никола
Published: October 2023

Миграције играју интегралну улогу у социо-културном ткиву Босне и Херцеговине, аспект који се често истражује, али је у литератури фрагментиран, укаљан историјским ревизионизмом и недостаје му дубинска, квалитативна анализа. Овај рад настоји да исправи ове недостатке, користећи објектив транснационализма да сецира замршену историју кретања становништва у овом региону. Методологија комбинује полуструктурирани преглед литературе и тематску анализу извора из различитих база података и библиотека. Резултат је систематски хронолошки преглед миграција на територији Босне и Херцеговине, подијељен у три јасна друштвено-историјска периода. Испитује се низ миграционих трендова који су обиљежили историју региона: од насељавања Илира и Словена до миграција у средњем вијеку, отоманске и хабзбуршке владавине, до модерних расељавања као што су миграције гастарбајтера и насилна расељавања становника усљед ратова. Синтетизујући перспективе запад- них, локалних и регионалних научника, рад наглашава да је историја миграција у Босни и Херцеговини сложен, међусобно повезан спектакл у којем је људска мобилност досљедно обликовала социокултурни контекст. Ова сложеност је наглашена главним увидом чланка – миграције на овим просторима су ризоматски феномен, фокални друштвено-културолошки маркер који дефинише не само прошлост већ и будућност Босне и Херцеговине. У том циљу, овај рад наглашава потребу за будућим квалитативним социо-антрополошким истраживањима миграција у Босни и Херцеговини како би се даље разоткрили њени дубоки утицаји и импликације на земљу и регион у цјелини.
Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction
Authors: Latini Sara , Venafra Veronica , Massacci Giorgia , Bica Valeria , Graziosi Simone , Pugliese Giusj Monia , Iannuccelli Marta , Frioni Filippo , Minnella Gessica , Marra John Donald , Chiusolo Patrizia , Pepe Gerardo , Helmer-Citterich Manuela , Mougiakakos Dimitrios , Boettcher Martin , Fischer Thomas , Perfetto Livia , Sacco Francesca
Published: October 2023

Currently, the identification of patient-specific therapies in cancer is mainly informed by personalized genomic analysis. In the setting of acute myeloid leukemia (AML), patient-drug treatment matching fails in a subset of patients harboring atypical internal tandem duplications (ITDs) in the tyrosine kinase domain of the FLT3 gene. To address this unmet medical need, here we develop a systems-based strategy that integrates multiparametric analysis of crucial signaling pathways, patient-specific genomic and transcriptomic data with a prior-knowledge signaling network using a Boolean-based formalism. By this approach, we derive personalized predictive models describing the signaling landscape of AML FLT3-ITD positive cell lines and patients. These models enable us to derive mechanistic insight into drug resistance mechanisms and suggest novel opportunities for combinatorial treatments. Interestingly, our analysis reveals that the JNK kinase pathway plays a crucial role in the tyrosine kinase inhibitor response of FLT3-ITD cells through cell cycle regulation. Finally, our work shows that patient-specific logic models have the potential to inform precision medicine approaches.
Notes from the editors
Authors: Nimehchisalem Vahid , Hung Yueh-Nu
Published: October 2023

This is our final issue in the eleventh volume of IJELS. As our readers may have noticed, since our previous issue, we have started to classify the articles under different sections depending on the area of literacy that they cover. The articles in the current issue fall into 10 different areas of literacy, including linguistic literacy, music and art literacy, numeracy literacy, social science literacy, sports literacy, historical literacy, emotional literacy, leadership studies literacy, science literacy, and finally, information literacy.
Cultural Studies and Heritage Education of Nanyin Performance Art in Quanzhou City, Fujian Province, China
Authors: He Xian , Sornyai Phiphat
Published: October 2023

Nanyin, a traditional Chinese music genre originating from Fujian Province, China, encompasses a wide range of singing and instrumental playing techniques. This study aims to analyze the historical development and performance form of Nanyin in Quanzhou, Fujian, China, employing an interdisciplinary approach that incorporates musicology, ethnomusicology, historical musicology, and organology, the study aims to gain a comprehensive understanding of Nanyin and its relevance to cultural studies and heritage education. Key informants, interviews, and observations were utilized as primary research tools, and a systematic data analysis approach was employed. The research results emphasize the enduring popularity and recognition of Nanyin. Nanyin’s development is traced through different periods, highlighting its ancient origins, fusion with diverse musical influences, professionalization, and contemporary revitalization. The performance forms of Nanyin encompass various styles, including duet singing, chorus singing, enchant singing, rotating singing, and group singing, demonstrating the artistic versatility and expressive capabilities of this cultural heritage. The research findings align with theoretical principles in the field of musicology and contribute to a deeper understanding of Nanyin’s cultural significance and its role in preserving China’s traditional culture.
Achievement Goal Orientations and Self-regulated Learning Levels among Pre-service Music Teachers: A Comparative Study
Authors: Boon İlkay Ebru Tuncer , Yurdabakan İrfan
Published: October 2023

This study examines how 2×2 Achievement Goal Orientations (AGO) relate to Self-Regulated Learning (SRL) levels in pre-service music teachers, considering variables that influence these orientations. The research found that female pre-service music teachers showed higher achievement orientations than males, especially in Learning-Approach and Learning-Avoidance Orientations. Different grade levels and study habits also impacted these orientations. Students who studied more displayed greater Learning-Approach Orientation and SRL. Females had higher SRL scores, particularly in Planning, Goal Setting, and Strategy Use. Academic achievers showed more positive orientations and lower Learning Dependency. These insights can guide interventions and support systems for pre-service music teachers, enhancing learning outcomes and teacher education programs.
Social Studies in Out-of-Class Learning Environments: A study on Teacher Candidates’ Views and Awareness
Authors: Adalar Hayati , Kılıç Hamide , Subaşı Yakup
Published: October 2023

This research aimed to investigate the awareness of out-of-class learning environments that can be utilized in social studies courses among both social studies teacher candidates and primary school teacher candidates. Social studies, with its interdisciplinary nature, has the potential to provide a wide array of out-of-class learning opportunities, and we aimed to explore this aspect. In pursuit of this objective, we sought to evaluate the extent of teacher candidates’ familiarity with these learning environments and their ability to establish connections between these settings and the content of the social studies course. In our research we used the descriptive case study which is one of the types of qualitative research methods. In this context, we carried out the qualitative data collection process within the framework of the interview technique through a ‘semi-structured interview form’ for the participating teacher candidates. We analyzed all the collected data using descriptive analysis. As a result of our analyses, we found that teacher candidates from both programs who had taken this course were able to identify a wide range of out-of-class learning environments and that the most common examples they mentioned were ‘museums, libraries, schoolyard, canteens and historical sites/places, excursions and laboratories’. However, we found that both groups had relative difficulty in associating these learning environments with the social studies curriculum and content. When we assessed whether this finding indicated a difference in the extent of the teacher candidates’ own branches and the course hours they had taken, we found that the examples of association of the teacher candidates with less social studies field education were far behind the examples of the social studies teacher candidates. Another significant finding from the research is that the teacher candidates were more capable of offering robust examples of associations related to out-of-class in-school learning environments compared to those associated with out-of-school learning environments.
The Effect of Gamification on Math Achievement, Motivation, and Learning Strategies in Flipped Classrooms
Authors: Pehlivan Fatma , Arabacioglu Taner
Published: October 2023

The aim of this research is to examine the effect of the gamification elements usage in the flipped classroom model on students’ academic success, motivation, and learning strategies in the 9th grade mathematics course clusters subject. The method of the study is a quasi-experimental research design with a pretest/post-test control group. The sample of the study comprises 38 vocational high school students who attend 9th grade. The experimental process was conducted for five weeks in the mathematics lesson on “Clusters.” Motivated Strategies for Learning Questionnaire (MSLQ) and achievement tests were used as data collection tools. According to the results of the research, while gamification did not make a significant difference in academic achievement and motivation, it caused a significant difference in the elaboration and peer learning dimensions of the learning strategies scale. Although this is not reflected in academic success in the research, it is considered to contribute positively to student performance. In addition, taking the group as the basis instead of the individual in the design of gamification is thought to prevent negativities, such as anxiety and jealousy, that may develop because of gamification, as well as contribute positively to student performance.
Development and Validation of a Teacher Self-Efficacy Scale for the Education of Refugee Students
Authors: Bağcı Can , Kayir Gökhan
Published: October 2023

Good education is only possible with highly qualified teachers. Being aware of these competences or deficiencies is also important for teachers’ professional development. In the last 15 years, refugee migration from the Middle East and Central Asia to Europe has challenged Turkey with the problem of refugee education. The aim of this research is to develop and assess a measurement tool to gauge teachers’ self-efficacy perceptions towards refugee students. The validity and reliability studies of the scale with 14 items and 4 sub-factors were carried out by exploratory and confirmatory factor analysis from the pool of 45 items created as a result of literature review. A second factor analysis was conducted to see whether the data fit into the predetermined factors. In the exploratory factor analysis phase of the study, 210 primary school teachers participated. The sampling group of the confirmatory factor analysis consisted of 200 teachers. It was concluded that the developed scale is a valid and reliable scale and can be used in the field of refugee education.
Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins
Authors: Sinegubova Maria V. , Orlova Nadezhda A. , Vorobiev Ivan I.
Published: October 2023

Background

The Chinese hamster ovary (CHO) cell line is the main host for the high-titer production of therapeutic and diagnostic proteins in the biopharmaceutical industry. In most cases, plasmids for efficient protein expression in CHO cells are based on the cytomegalovirus (CMV) promoter. The autologous Chinese hamster eukaryotic translation elongation factor 1α (EEF1A1) promoter is a viable alternative to the CMV promoter in industrial applications. The EEF1A1 promoter and its surrounding DNA regions proved to be effective at maintaining high-level and stable expression of recombinant proteins in CHO cells. EEF1A1-based plasmids’ large size can lead to low transfection efficiency and hamper target gene amplification. We hypothesized that an efficient EEF1A1-based expression vector with a long terminal repeat fragment from the Epstein-Barr virus (EBVTR) could be truncated without affecting promoter strength or the long-term stability of target gene expression.

Methods

We made a series of deletions in the downstream flanking region of the EEF1A1 gene, and then in its upstream flanking region. The resulting plasmids, which coded for the enhanced green fluorescent protein (eGFP), were tested for the level of eGFP expression in the populations of stably transfected CHO DG44 cells and the stability of eGFP expression in the long-term culture in the absence of selection agents.

Results

It was shown that in the presence of the EBVTR fragment, the entire downstream flanking region of the EEF1A1 gene could be excluded from the plasmid vector. Shortening of the upstream flanking region of the EEF1A1 gene to a length of 2.5 kbp also had no significant effect on the level of eGFP expression or long-term stability. The EBVTR fragment significantly increased expression stability for both the CMV and EEF1A1 promoter-based plasmids, and the expression level drop during the two-month culture was more significant for both CMV promoter-based plasmids.

Conclusion

Target protein expression stability for the truncated plasmid, based on the EEF1A1 gene and EBVTR fragment, is sufficient for common biopharmaceutical applications, making these plasmid vectors a viable alternative to conventional CMV promoter-based vectors.
Evaluation of SARS-CoV-2 identification methods through surveillance of companion animals in SARS-CoV-2-positive homes in North Carolina, March to December 2020
Authors: Gin Taylor E. , Petzold Elizabeth A. , Uthappa Diya M. , Neighbors Coralei E. , Borough Anna R. , Gin Craig , Lashnits Erin , Sempowski Gregory D. , Denny Thomas , Bienzle Dorothee , Weese J. Scott , Callahan Benjamin J. , Woods Christopher W.
Published: October 2023

We collected oral and/or rectal swabs and serum from dogs and cats living in homes with SARS-CoV-2-PCR-positive persons for SARS-CoV-2 PCR and serology testing. Pre-COVID-19 serum samples from dogs and cats were used as negative controls, and samples were tested in duplicate at different timepoints. Raw ELISA results scrutinized relative to known negative samples suggested that cut-offs for IgG seropositivity may require adjustment relative to previously proposed values, while proposed cut-offs for IgM require more extensive validation. A small number of pet dogs (2/43, 4.7%) and one cat (1/21, 4.8%) were positive for SARS-CoV-2 RNA, and 28.6 and 37.5% of cats and dogs were positive for anti-SARS-CoV-2 IgG, respectively.
From the Cloud to the Landfill: The Case of the Agbogbloshie Makerspace Platform and Akwasi Bediako Afrane’s TRONS
Authors: Khalatbari Cyrus
Published: October 2023

This contribution sheds light on discarded electronics repair in Accra, Ghana. After placing these practices in dialogue with the Western and Eurocentric narratives around the materiality of digital interactions and infrastructure, it delves into two arts and design contexts that gravitate around the electronic waste landfill and processing site of Agbogbloshie (Ghana). The first case study is the Agbogbloshie Makerspace (AMP), a critical making (and unmaking) platform empowering local repairers and dismantlers through open-source collaborative design methods. The contribution then focuses on the work of Akwasi Bediako Afrane, a Ghanaian media artist who re-appropriates discarded computers to critique and speculate on our sociotechnical condition. Situating these initiatives in the light of our broader dominant internet and computing narratives, the article situates the importance of these practices in order to tackle and raise awareness about the planetary electronic waste condition we live in.
Going for Gold: A Medal of Dishonor
Authors: Fry Tony , Detonante Diseño
Published: October 2023

The work sets out to show the imperative of design and its ambiguity. The methodology used was narrative theory. The result was a polemic. The conclusion was: for repair to be ethical, it has to be predicated upon ethical norms.
Principles of Teaching English to Young Learners: Preservice Teachers’ Applications in Young Learner Classrooms
Authors: KARA Selma
Published: October 2023

The success of teaching foreign languages to children depends on teachers’ professional preparation; therefore, it is important to view teacher education programs. The current study investigated the preservice teachers’ perceptions of the principles of teaching a foreign language to young learners, their stated activity usage, and the compatibility of their teaching practices with the theory and principles that they learned in their teacher education program. The participants were 50 preservice teachers who were studying at a foreign language teaching department and practicing teaching at primary schools. Data was obtained through a questionnaire, interviews, lesson plans, and observations, which were compared and cross-checked to verify reliability and validity. The results revealed that preservice teachers are aware of the characteristics of young learners; they know the principles of teaching a foreign language to young learners and implement visuals, games, and puzzles in their teaching practice. However, they do not implement storytelling or role-play activities. The study found that preservice teachers know the theory and principles but have difficulties with their implementation during their practice teaching. It is concluded that by gaining insights into preservice teachers’ implementations of the theory and principles of teaching young learners, teacher educators may better design teacher training programs.
Lisans Öğrencilerinin Paranormal İnanç Düzeylerinin Değerlendirilmesi
Authors: ULUKAYA ÖTELEŞ Ülkü , KOÇOĞLU Erol , DEMİR Fatıma Betül
Published: October 2023

Paranormal inançlar, bilimsel manada açıklanamayan astroloji, batıl inanç, olağandışı yaşam formları gibi duyu dışı olgulardır. Bu olgular toplumların yaşam biçimleri üzerinde etkili olmakla birlikte bazı toplumların çağ dışı tutum ve davranışlara sahip olmasına yol açmaktadır. İlgili durum toplumların bilimsel dünyaya uyumu ve gelişimini zorlaştırmaktadır. Bu inançlar özellikle gençlerin yaşam biçimleri ve geleceklerini şekillendirme noktasında ön plana çıkmaktadır. Genç nüfusun önemli bir kısmının lisans düzeyinde yer alması ve bu düzeyde yer alan gençlerin bilimde karşılığı olmayan olgu ve durumlar olan paranormal inançları daha bilinçli bir şekilde değerlendirebilecekleri düşünülmektedir. Bu bağlamda yapılan bu araştırmada, lisans öğrencilerinin paranormal inanç düzeylerinin belirlenerek, değerlendirilmesi amaçlanmıştır. Paralel karma yöntem deseni ile tasarlanan bu araştırmanın nicel çalışma grubunu 357 lisans öğrencisi, nitel çalışma grubunu ise 30 lisans öğrencisi oluşturmaktadır. Araştırmada veri toplama aracı olarak “Paranormal İnanç Düzey Ölçeği” ve “Yarı Yapılandırılmış Görüşme Formu” kullanılmıştır. Elde edilen nicel verilerin analizinde parametrik testlerden t-testi, ANAVO; nitel verilerin analizinde ise içerik analizi kullanılmıştır. Araştırmadan elde edilen sonuçlara göre, lisans öğrencilerinin paranormal inançlarının orta düzeyde olduğu ve çeşitli değişkenler (cinsiyet, sınıf düzeyi vb.) bağlamında farklılık gösterdiği görülmektedir. Ayrıca lisans öğrencileri paranormal inançların günlük yaşamlarına çeşitli yansımaları olduğunu belirtmişlerdir. Bu sonuçlar doğrultusunda, öğrencilere verilecek bilimsel eğitim ile paranormal inançları eleştirel bağlamda değerlendirmelerine katkı sağlanabilir.
Categorization of a Universal Coding System to Distinguish Use of Durable Medical Equipment and Supplies in Pediatric Patients
Authors: Hotz Arda , Sprecher Eli , Bastianelli Lucia , Rodean Jonathan , Stringfellow Isabel , Barkoudah Elizabeth , Cohen Laurie E. , Estrada Carlos , Graham Robert , Greenwood Jonathan , Kyle Jennifer , Mann Nina , Pinkham Maria , Solari Toni , Rosen Rachel , Saleeb Susan , Shah Ankoor S. , Watters Karen , Wells Sarah , Berry Jay G.
Published: October 2023

Importance

Although durable medical equipment and supplies (DMES) are commonly used to optimize the health and function in pediatric patients, little is known about the prevalence of use and spending on DMES.

Objective

To categorize the Healthcare Common Procedure Coding System (HCPCS) for distinguishing DMES types, and to measure the prevalence and related spending of DMES in pediatric patients using Medicaid.

Design, Setting, and Participants

This study is a cross-sectional analysis of the 2018 Merative Medicaid Database and included 4 569 473 pediatric patients aged 0 to 21 years enrolled in Medicaid in 12 US states from January 1 to December 31, 2018. Data were analyzed from February 2019 to April 2023.

Exposure

DMES exposure was identified with the Centers for Medicare & Medicaid Services HCPCS codes. Three pediatricians categorized HCPCS DMES codes submitted by vendors for reimbursement of dispensed DMES into DMES types and end-organ systems; 15 expert reviewers refined the categorization (2576 DMES codes, 164 DMES types, 14 organ systems).

Main Outcomes and Measures

The main outcome was DMES prevalence & Medicaid spending. The χ2 test was used to compare DMES prevalence and Wilcoxon rank sum tests were used to compare per-member-per-year (PMPY) spending by complex chronic conditions (CCC).

Results

Of the 4 569 473 patients in the study cohort, 49.3% were female and 56.1% were aged 5 to 15 years. Patients used 133 of 164 (81.1%) DMES types. The DMES prevalence was 17.1% (95% CI, 17.0%-17.2%) ranging from 10.1% (95% CI, 10.0%-10.2%) in patients with no chronic condition to 60.9% (95% CI, 60.8%-61.0%) for patients with 2 or more CCCs. The PMPY DMES spending was $593, ranging from $349 for no chronic condition to $4253 for 2 or more CCCs. Lens (7.9%), vision frames (6.2%), and orthotics for orthopedic injury (0.8%) were the most common DME in patients with no chronic condition. Enteral tube / feeding supplies (19.8%), diapers (19.2%), lower extremity orthotics (12.3%), wheelchair (9.6%), oxygen (9.0%), and urinary catheter equipment (4.2%) were among the most common DMES in children with 2 or more CCCs.

Conclusions and Relevance

In this cross-sectional study, HCPCS distinguished a variety of DME types and use across pediatric populations. Further investigation should assess the utility of the HCPCS DMES categorization with efforts to optimize the quality and safety of DMES use.
Exploiting signaling rewiring in cancer cells with co‐existing oncogenic drivers
Authors: Chiarle Roberto , Ambrogio Chiara
Published: October 2023

The development of tailored therapies designed to specifically target driver oncogenes has initiated a revolutionary era in cancer biology. The availability of a growing number of selective inhibitors has generated novel experimental and clinical paradigms. These represent an opportunity and a challenge for researchers and clinicians to delve deeper into the intricate dynamics of cancer development and response to treatment. By directly inhibiting key driver oncogenes involved in tumor initiation and progression, scientists have an unprecedented opportunity to conduct longitudinal and clonal evolutionary studies of how cancer cells adapt, rewire, and exploit conflictive or overlapping signaling dependencies in response to treatment in vitro and in vivo. This challenge has to be progressively resolved to discover more effective and personalized cancer therapies.
A marsh multimodel approach to inform future marsh management under accelerating sea‐level rise
Authors: Mitchell Molly , Nunez Karinna , Herman Julie , Tombleson Christine , Mason Pam
Published: October 2023

Accelerating sea‐level rise combined with the stresses of human land use threatens the persistence of tidal marshes. The proper management of existing marshes and the conservation of lands for marsh migration require a synthesis of factors affecting future marsh evolution.

There are a number of existing marsh models, with different parameters and run at different scales, that can assist in this type of assessment. However, as with many models forecasting future conditions, there is no clearly identified ‘best’ model and they all perform slightly differently across different scenarios and with different suites of available data inputs.

In this paper, we worked with local and regional managers to inform the development of an ensemble methodology that uses results from multiple marsh models in conjunction with social, land use and environmental data to inform marsh management, conservation and restoration under sea‐level rise.

The methodology was developed and tested in three locations in the Virginia portion of the Chesapeake Bay, United States, using existing marsh migration models already run throughout the Bay. Stakeholder groups of local decision makers and a steering committee composed of regional managers were engaged in the process to ensure that the resulting methodology met current management needs.

The need for a multimodel approach to identifying marsh migration pathways was supported by the marsh migration comparison done during methodology development which showed disparate results from multiple marsh migration models. Five existing marsh model outputs were combined into a single Marsh Migration Corridor Envelope (MMCE), which encompasses the potential area of current upland expected to become marsh under a selected sea‐level rise scenario.

Within the identified MMCE, land covers were assessed for suitability for marsh support and the socio‐economic context of the parcels of land was considered. Last, the current condition of existing marsh on the properties was assessed to determine preservation activities that can increase their longevity. Together, these pieces of information inform a physical and sociological understanding of tidal marshes that can allow for a management framework that incorporates both current and future concerns.
T1−/T2‐weighted ratio reveals no alterations to gray matter myelination in temporal lobe epilepsy
Authors: Denis Colin , Dabbs Kevin , Nair Veena A. , Mathis Jedidiah , Almane Dace N. , Lakshmanan Akshayaa , Nencka Andrew , Birn Rasmus M. , Conant Lisa , Humphries Colin , Felton Elizabeth , Raghavan Manoj , DeYoe Edgar A. , Binder Jeffrey R. , Hermann Bruce , Prabhakaran Vivek , Bendlin Barbara B. , Meyerand Mary E. , Boly Mélanie , Struck Aaron F.
Published: October 2023

Short‐range functional connectivity in the limbic network is increased in patients with temporal lobe epilepsy (TLE), and recent studies have shown that cortical myelin content correlates with fMRI connectivity. We thus hypothesized that myelin may increase progressively in the epileptic network. We compared T1w/T2w gray matter myelin maps between TLE patients and age‐matched controls and assessed relationships between myelin and aging. While both TLE patients and healthy controls exhibited increased T1w/T2w intensity with age, we found no evidence for significant group‐level aberrations in overall myelin content or myelin changes through time in TLE.
Fixed‐time tracking control of manipulators based on a fast variable power reaching law
Authors: Li Dan , Chen Ming , Li Yingsen , Peng Kaixiang , Wu Libing
Published: October 2023

As for the problem of trajectory tracking of a two‐joint series manipulator, a novel fixed‐time control scheme is proposed based on non‐singular fast terminal sliding mode (NFTSM) control and a fast variable power reaching law. The innovation of the proposed method is: (1) by employing the NFTSM surface, we solve the singularity problem existed in traditional terminal sliding mode surface. (2) The convergence rate is increased by 50% by the combination of fixed‐time control and NFTSM surface control. (3) A new fast variable power reaching law is presented, which combines the advantages of the double power reaching law and the fast power reaching law, and it effectively improves the reaching rate and reduces the amplitude by 40–60 N m. Theoretical analysis proves that the better tracking performance is obtained, and its convergence time upper limit is not affected by the initial states of the system. Finally, the effectiveness and feasibility of our controller are verified through a numerical simulation.