bluuebunny/crossref_metadata_2025 huggingface dataset:
Enfoques en las relaciones civiles-militares y la cultura de defensa
Authors: De León Rodríguez, ERD General de Brigada Luis Francisco
Published: May 2024

Los temas relacionados con las relaciones civiles militares y cultura de defensa son muy limitados, a pesar de los estu­dios e investigaciones que se divulgan sobre los mismos. Los cambios sociales y culturales que se han vivido en las últimas décadas y que han repercutido en el aspecto social del queha­cer militar, tanto en el plano organizacional, como en sus di­mensiones de profesión, de institución y como grupo social, llama a preocupación, toda vez que entran en contradicción el ser con el deber ser militar. Junto con resaltar la impor­tancia de estos temas, se busca estimular su profundización por parte de quienes trabajan en el área de la defensa, y sobre todo, por aquellos llamados a ejercer el liderazgo militar en el futuro.
Las Fuerzas Armadas frente al COVID-19
Authors: Mercedes Cepeda, ERD Mayor General Víctor
Published: May 2024

Los Estados, desde su fundación, siendo entes previsores ante las posibles afectaciones a sus soberanías y autodeter­minación crean las organizaciones que con sus empeños garantizan su supervivencia; estas son las Fuerzas Armadas misionadas a la prevención de las amenazas y a dar las res­puestas adecuadas y oportunas. Junto con el desarrollo, el progreso, la evolución global y sus consecuencias, las ame­nazas cambian, mutan, y se crean hasta el punto de que las convencionales pasan a un lejano segundo plano ante la presencia de amenazas emergentes, que rompen los con­ceptos tradicionales del empleo de las Fuerzas Armadas, obligando a establecer doctrinas sobre nuevos e inimagi­nables paradigmas de las amenazas que sobrepasan todos los límites, convirtiéndose en crisis que llegan a trascender los espacios geográficos de los Estados donde se originan y pasan a ser crisis regionales o globales, esto debido a que al no poder preverse la amenaza, sus efectos, su alcance, le­talidad y consecuencias, las respuestas se hacen, de inicio, como simple acción inmediata fruto de la sorpresa, y por desconocerse la respuesta efectiva, así como el verdadero daño a la población, a las organizaciones del Estado o a sus objetivos nacionales, lo que compromete a todas las insti­tuciones, obliga al estamento político a su total atención, daña la economía y ocupa en su totalidad a las Fuerzas de la Defensa y de la Seguridad, tal es el caso de la pandemia COVID-19.
Enfoque estratégico-operacional en la cooperación hemisférica occidental y lecciones aprendidas por la Fuerza Aérea de República Dominicana ante la crisis sanitaria
Authors: Rivas Díaz, FARD Coronel Piloto (DEMA) Mario Alberto
Published: May 2024

La incidencia del nuevo coronavirusSARS-CoV-2; un enemigo invisible e intangible que golpea a las naciones de forma volátil e inesperada y que desafortunadamente ha dejado a su paso cifras mortales alarmantes, pone de manifiesto la importancia de las fuerzas militares cuando toman cursos de acción para mitigar esos efectos. Ante tal adversidad, el liderazgo del componente aéreo del hemisferio occidental ha sido referente en el apoyo a nuestros pueblos, empleando sus capacidades eficazmente ante este escenario incierto y complejo, de una crisis sanitaria global que no presenta un cese visible a su impacto. La Fuerza Aérea de República Dominicana ha empeñado sus medios a responder tomando de referencia lecciones aprendidas de sus aliados regionales e implementando buenas prácticas para sostener las operaciones y respaldar al mando estratégico, apoyar a otras organizaciones de respuesta de emergencia y garantizar la protección del espacio aéreo nacional en medio de la pandemia.
El control restrictivo de la frontera México-EUA con pretexto de la migración irregular. Síntoma de un capitalismo en crisis
Authors: Morales Cardiel Dr. Jorge
Published: May 2024

La frontera norte mexicana que comparte con Estados Unidos juega un papel fundamental en el tratamiento político y administrativo de las migraciones irregulares provenientes del Sur Global. Su creciente securitizacion la ha convertido en uno de los síntomas más marcados de las crisis y contradicciones del capitalismo, debido a esto se presenta un control restrictivo en este espacio transfronterizo con pretexto de la migración.
Entre la defensa y la integración fronteriza: Una aproximación desde el turismo
Authors: Llugsha Guijarro Víctor , Salazar Duque Diego
Published: May 2024

Al analizar la cuestión de defensa y seguridad de las fronteras, nos enfrentamos a un fenómeno de continuos cambios y gran complejidad. Ante la necesidad de proteger los territorios estatales, la visión que se tiene de las fronteras responde a un enfoque de la defensa de la soberanía, por lo que el enfoque militarista en la gestión de estas áreas se ha impuesto a lo largo del tiempo. Por otra parte, el crecimiento del turismo ha generado una mayor apertura de las fronteras, sobre todo cuando está asociado a la posibilidad de mejorar el desarrollo económico del territorio, situación que plantea nuevos retos en términos de seguridad.El turismo, impulsado por esta apertura de fronteras, representa una oportunidad de desarrollo para las regiones limítrofes.El turismo fronterizo aprovecha la fusión cultural de las regiones limítrofes y depende de las asimetrías complementarias que le son inherentes. Sin embargo, las diferencias socioeconómicas y la inestabilidad política pueden afectar tanto a los residentes como a los turistas. Las fronteras presentan un reto multidimensional en cuanto a seguridad y defensa, pero también ofrecen oportunidades de desarrollo a través del turismo. Es crucial abordar estos desafíos de manera integral, teniendo en cuenta tanto los aspectos de defensa como las posibilidades económicas y culturales que el turismo puede brindar a las regiones fronterizas.
Impact of agricultural price policy on farm harvest and wholesale prices of legumes in Maharashtra
Authors: AB Thakare  , NV Shende  , AA Bhopale
Published: May 2024

Legumes have been used as an entry point to improve productivity, food security in terms of nutrition and availability aspect and income for smallholder farmers. The findings reveal that the growth in the area of soybean, tur and gram was significantly increased and the production growth in all the selected crops was significantly increased. Productivity growth was significantly increased in gram on the other hand it was stagnant in case of soybean. The high variability in WSPs in almost all the selected crops indicated that all the crops were volatile in terms of prices and also that large variability in MSP were observed. Significantly positive growth rates were observed for FHP and MSP of all the selected crops.
The Polish Armed Forces at the 25th Anniversary of Poland’s NATO Membership
Authors: Kowalik Tomasz Krzysztof
Published: May 2024

Streszczenie

25-letnie członkostwo Polski w NATO w 2024 r. nasuwa pewne refleksje i wnioski. Siły Zbrojne RP odgrywają rosnącą rolę w NATO, a ich wpływ na zdolności operacji obronnej NATO rośnie. Skutkuje to rekomendacjami dotyczącymi dalszego rozwoju sojuszniczych struktur dowodzenia w Polsce, rozbudowy sojuszniczej infrastruktury wojskowej w regionie, obsady stanowisk natowskich przez Polskę, zwiększenia rotacyjności kadry, wzmocnienia zakresu doskonalenia znajomości języka angielskiego u kadry Wojska Polskiego, a także niektórych dalszych kierunków rozwoju SZ RP.

Cel i metody badawcze

Celem artykułu jest przedstawienie rozwoju i aktualnego stanu Sił Zbrojnych RP w dobie 25-lecia ich członkostwa w NATO, a zarazem na podstawie osobistych doświadczeń empirycznych służby w strukturach natowskich jak i krajowych oraz analizy literatury i dokumentów normatywnych NATO, przeprowadzenie dyskusji i dokonanie oceny potencjału Sił Zbrojnych RP do przejęcia dowodzenia potencjalną multidomenową operacją obronną NATO.

Wnioski / rekomendacje

- Zacząć traktować struktury sojusznicze NATO jako dowództwa, które włączą się w operację obronną Polski.
- Synchronizacja planów sojuszniczych i narodowych.
- Zacieśniać współdziałanie pomiędzy korpusami na terenie Polski i dążyć do ich zwiększonej interoperacyjności.
- Nadać dywizji MNDNE odpowiedni priorytet i podporządkować jej jednostki bojowe i jednostki wsparcia.
- Zaoferować przeniesienie dowództwa JLSG w Brunssum na stałe do Polski.
- Ubiegać się przez jednostki SZ RP o udział w ćwiczeniach CPX w JFTC.
- Ubiegać się o rozbudowę sojuszniczej infrastruktury na terenie Polski za pomocą funduszy NSIP.
- Dążyć do rozbudowy systemu rurociągów CEPS z Niemiec do Polski.
- Dążyć do przekształcenia natowskiej batalionowej grupy bojowej FLF w Brygadę FLF.
- Przywrócić w Ustawie o Obronności Ojczyzny zasadę kadencji i wprowadzić zasadę cyklicznej rotacji kadr.
- Przyjąć strategię uzyskania w SZ RP wskaźnika 100% znajomości języka angielskiego u kadry oficerskiej.
Multinational division north-east in the NATO command system
Authors: Hadam Grzegorz
Published: May 2024

Sytuacja geopolityczna na świecie zmienia się obecnie bardzo dynamicznie. Wszystkie te zmiany uwidaczniają jednak, że środkiem ciężkości wysiłków NATO jest flanka wschodnia. Autorzy opracowania przedstawiają jak w świetle tych zmieniających się uwarunkowań ewoluuje podejście NATO do zagrożeń ze wschodu. Przedstawiona jest geneza powstania i historia Dowództwa Wielonarodowej Dywizji Północny-Wschód. Nakreślone zostały jej główne zadania i plany rozwoju jako ważnego elementu w architekturze bezpieczeństwa sojuszu na wschodniej flance NATO.
Solution Focused Trifecta: A Guide to Being Solution Focused. Workbook for School Counsellors by Joe George
Authors: Blond Booth Lisa
Published: May 2024

Joe George’s workbook on the Solution Focused model is easy-to-read, thoughtful and concise. Geared towards school counsellors and conversations that might be shorter than a standard therapy session, it supports an informal SF model well attuned to school environments, making it equally easily to co-construct both quick hallway conversations with students or contacts with colleagues and families.
Jaja Bebangkit as an Embodiment of the Offering Which Contains Aesthetic Value
Authors: Budiarta I Dewa Putu Gede , Buana Anak Agung Ngurah Gede Surya
Published: May 2024

Hinduism in Bali is a religion that is very full of offerings as gratitude to God in all His manifestations, as well as offerings to the ancestors, also to the Rsi which is translated as a debt, so that all people feel obliged to do the offering. In carrying out the obligation to make offerings with a series of ceremonies, it is always packed with a series that is very symbolic and has a high aesthetic value. Beauty or aesthetics is a very important consideration in carrying out a series of offerings, starting from objects as manifestations of ceremonies, mantra words pronounced in beautiful rhythms, to the attitudes of the performers of offerings with beautiful attitudes and movements in the form of dances. Bebangkit is a series of ceremonies with symbolic meaning which means the manifestation of the great world, contained with symbols of all contents in this universe.
Visualization Values of Pranayama in Abstract Statue Art Works
Authors: Merta I Dewa Putu
Published: May 2024

This article is the creation of research-based works related to the values of Pranayama. Pranayama is one of the yoga activities that puts more emphasis on breathing, body movement and is combined with concentration. There is a holy relationship or a combination of breathing, body work and concentration which can create a balance between body and soul (subtle body and gross body). The union between body and soul can occur when the combination of breath, body movement (hand movement), and concentration. The meaning contained in pranayama tantra is balance. This theme is taken from a meaning contained in tantra pranayama. The emergence of this theme explicitly refers to the object itself based on the fact that an artist has a sense of sensitivity in observing, dismantling, and peeling off an object as a source of inspiration. The method of creation is a method developed by Hawkins to create works of art systematically. The stages of creating an art work that outlines the design process for the creation of an art work according to the stages of the work, from the inspiration (idea) to the design, to the embodiment of the artwork. By cultivating the balance value contained in tantra pranayama it is visually manifested into three-dimensional works of art. The concept of space and field is the basis for visualizing it, so that it can give birth to monumental abstract sculptures.
Algorithmic Decision Making: Can Artificial Intelligence and the Metaverse Provide Technological Solutions to Modernise the United Kingdom’s Legal Services and Criminal Justice?
Authors: Singh C.
Published: May 2024

Artificial intelligence (AI), machine learning (ML) and deep learning (DL) have had a profound impact on various sectors including Banking (Fin Tech), Health (HealthTech) and Charitable Fundraising (Charity Tech). The ‘natural’ ability of an AI system to independently perform and, often, outthink its human-counter parts by developing ‘intelligence’(simulating human intelligence) through its own experiences and processing deep layers of information i.e., complex representations of data, and learn has resulted in astounding improvements in the completion of tasks that are complex and technical, time-consuming.AI, with the ease of working with the most granular level of detail, can identify people and objects, recognise voices, uncover patterns and, in advance, screen for problems. Yet, RegTech (or LawTech/LegalTech) has not seen the same level of advancement. AI can provide solutions and enormous economic, political, and social benefits – in terms of public service administration. The purpose of this article is to explore advents in AI (ML and DL) and whether the criminal justice system, in the United Kingdom (UK), which is heavily overburdened, could benefit from some of the advances that have taken place in other sectors and jurisdictions, and whether automation and algorithmic decision making could be used to modernise it. This research draws on domestic and international published law, regulation, and literature, and isset out in six parts, the first partre views the position of the criminal justice system i.e., issues, part two then looks at relative technological advancements in AI, and the Metaverse. Part three explores current advents in AI relating to RegTech (LawTech/LegalTech) and how, if at all, the CJS can use this technology. Part four explores what aspects of the U.K.’s CJS would be fit for automation. Part five focuses on those matters pertaining to AI that pose problems in relation to matters in part 4 i.e., AI discrimination and bias, and explores safeguarding and mitigation including the requirement for explanation as set out in the GDPR. Part six concludes the discussion with some recommendations, as at, January 2024. It is suggested that AI and algorithmic decision making, with the correct legal framework and safeguards in place, could assist in modernising the CJS focussed legal functions, services in law firms, innovating for the next decade. This work is original and timely given the increased debate relating to how AI can assist in modernising the U.K.’s CJS, the global criminal justice challenges, solutions, and what, if any, role the Metaverse can play.
Guía didáctica para mejorar la fluidez de la lectura: caso de la Unidad Educativa Reino de Inglaterra
Authors: Pinos Sumba Erika Yadira , Herrera Navas Cristopher David
Published: May 2024

Es fundamental que los estudiantes desarrollen destrezas para comunicarse y comprender el mundo mediante la palabra escrita, sin embargo, es notoria la presencia de dificultades en la fluidez lectora, que impactan negativamente el desarrollo estudiantil. El objetivo de este estudio fue crear una guía didáctica para la mejora de la fluidez lectora en los estudiantes de tercer año. La metodología posee un enfoque mixto, diseño anidado concurrente de varios niveles, alcance explicativo y método inductivo. Se empleó un muestreo por conveniencia, seleccionado 18 estudiantes y un docente. La técnica de recolección de datos empleada fue la observación directa. Como instrumentos, se han diseñado y validado un cuestionario semiestructurado para comprender el problema de la fluidez lectora; y una lista de cotejo para el pretest y postest. Como resultados, el pretest diagnosticó que los estudiantes tienen dificultades en todos los indicadores de la fluidez lectora (ritmo, precisión, pausas, volumen y parámetro lector). Asimismo, la docente menciona emplear como principal método, las lecturas individuales para la enseñanza. Por ello, se aplica una guía didáctica desde el juego y la interactividad como principios durante 12 clases, logrando que los estudiantes alcancen las destrezas para la fluidez lectora, 44% en ritmo, 39% en precisión, 50% en volumen y 33% en parámetro lector. Se concluye que, el problema diagnosticado requiere de una intervención permanente y continua para obtener resultados mayores, pese a que la guía a tenido un impacto significativo, se debe continuar cambiando la cultura de enseñanza, fomentando la aplicación de estrategias activas
El uso de podcasts para mejorar las habilidades auditivas de los estudiantes de 9º grado en una escuela secundaria privada en la ciudad de Milagro
Authors: Eras Oñate Evelin Gicely , Hoyos Zárate Lady Mariam , Rivas Ortiz Margarita Fabiola , Estrada Alarcón Diana Xiomara
Published: May 2024

En Ecuador, los estudiantes de inglés como lengua extranjera perciben la escucha como una de las habilidades más complejas de dominar. Debido a los desafíos que conlleva el dominio de esta habilidad, se ha identificado la necesidad de encontrar soluciones efectivas. La integración de herramientas tecnológicas como los podcasts es una forma efectiva de mejorar las habilidades de escucha, ya que son recursos altamente motivadores y atractivos y se pueden seleccionar de acuerdo con los intereses, niveles y edad de los estudiantes de EFL. Por lo tanto, la presente investigación, realizada en una escuela secundaria privada en la ciudad de Milagro, Guayas, Ecuador, tuvo como objetivo descubrir qué tan efectivo es el uso de podcasts para mejorar las habilidades auditivas de los estudiantes de inglés como lengua extranjera de noveno grado. Durante el estudio, se empleó un enfoque cuantitativo y los participantes fueron 20 estudiantes de noveno grado cuyas edades oscilaban entre los 12 y los 13 años y tenían un nivel de competencia A1. De acuerdo con los resultados, durante el pre-test, la mayoría de los participantes obtuvieron puntajes 'regulares' y 'malos'; Por el contrario, en el post-test, la mayoría mejoró a puntuaciones "regulares" y "buenas". Por lo tanto, se concluyó que hubo una mejora significativa en las habilidades de escucha de los participantes después de recibir lecciones de comprensión auditiva empleando podcasts como principal recurso didáctico.
KDM3A knockdown regulates COMP, LOX, COL8A1 and ACOT1 genes in myocardial fibrosis
Authors:   Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, Alzhrani Abrar A , Rasool Mahmood ,   Center of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, Karim Sajjad ,   Center of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, Alhejin Ahmed ,   Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, Haque Absarul ,   King Fahd Medical Research Center, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Morsi Mohamed ,   Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, Nabil Alama Mohamed ,   Department of Cardiology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia, Pushparaj Peter Natesan ,   Center of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
Published: May 2024

Cardiovascular disease (CVD) is one of the main causes of death in Saudi Arabia. Cardiac remodeling plays a critical role in the pathophysiology of heart failure. Major focus of our study was to identify crucial genes involved in the pathological remodeling of the heart caused by pressure overload. We utilized various in-silico tools to analyze and interpret microarray data obtained from the Gene Expression Omnibus (GEO) database (GSE120739), including GEO2R analysis, Metascape analysis, WebGestalt analysis, and IPA (Ingenuity pathway analysis). Our findings indicate that certain genes, including Cartilage Oligomeric Matrix Protein (COMP), collagen type VIII alpha 1 chain (COL8A1) and Lysyl Oxidase (LOX) under the influence caused by knockdown of KDM3A, were down regulated by the extracellular matrix pathway. Moreover, genes, such as Acyl-CoA Thioesterase 1 (ACOT1) were up regulated by the fatty acid metabolism pathway. Overexpression of lysine-specific demethylase 3A (KDM3A) leads to the up regulation of fibrosis-related genes COMP, COL8A1, and LOX and the down regulation of ACOT1, result in enhanced fibrosis and heart failure. Our results suggest that COMP, COL8A1, LOX, and ACOT1 warrant further investigation in the development of cardiac fibrosis and as potential biomarkers for causing heart failure.
In vitro analysis of material micro-leakage in pit and fissure sealants
Authors:   Department of Pedodontics and Preventive Dentistry, Government Dental College and Hospital, Ahmedabad, Gujarat, India, Mittal Swati , Panwar Pratyaksha Singh ,   Department of Dentistry, Government Doon Medical College, Dehradun, Uttarakhand, India, Rawal Aabha ,   Department of Conservative Dentistry and Endodontics, Faculty of Dental Science, Dharamsinh Desai University, Nadiad, Gujarat, India, Mansuri Mohomedkaif ,   Department of Public Health Dentistry, Ahmedabad Dental College and Hospital, Ahmedabad, Gujarat, India, Bagchi Anandamoy ,   Department of Pedodontics & Preventive Dentistry, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, India, Pandey Monika ,   Department of Paediatric and Preventive Dentistry, R.K.D.F. Dental College and Research Center, Bhopal, Madhya Pradesh, India, Surana Pratik ,   Department of Pedodontics and Preventive Dentistry, Maitri College of Dentistry and Research Centre, Durg, Chhattisgarh, India
Published: May 2024

A preferable choice of material offers superior resistance against micro-leakage for clinical applications in preventing dental caries in pits and fissures is of interest. A total of 45 extracted human premolars were cleaned, stored in a saline solution, and randomly divided into three groups, each intended for treatment with one of the sealants: Fuzi VII, ClinPro, and Embrace Wetbond. The application of the sealants followed the manufacturers' instructions strictly. The teeth were subjected to thermal cycling to simulate oral conditions. Marginal micro-leakage was then assessed by dye penetration method using a 0.5% methylene blue dye. Teeth were sectioned, and dye penetration was measured under a stereomicroscope. The results showed that all the tested materials exhibited some degree of micro-leakage. Within the limitations of this in vitro study, it was concluded that Embrace Wetbond exhibited superior performance in terms of minimizing marginal micro-leakage among the tested pit and fissure sealants.
Congenital ocular and its adnexal anomalies among Indian pediatric age
Authors:   Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India, Chava Preethi , Chaitra MC ,   Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India, Raveena J ,   Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India, Padmini Amulya ,   Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India
Published: May 2024

An analysis of the congenital etiologies of ocular morbidity in children of age 0-12 years is of interest. Hence, this study was conducted over a period of 2 years from Jan 2021- Dec 2023 at RL Jalappa Hospital and Research center that is attached to Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, India. Out of 56 patients, 57% were male and 43% were female children. 31 (55%) of mothers belonged to age group between 20-30 years and 24 (43%) between 31-40 years and 1(2%) between 41-50 years. Out of 56 patients, 14 (25%) of them had positive family history. 34 (61%) of them had consanguious marriage. 14 parents (41%) out of 34 are married to second degree consanguinity (brother/sister/grandparent/grandchild) and 20 (59%) belonged to third degree consanguinity (aunt/uncle/niece/nephew/great-grandparent/great-grandchild). Bilateral involvement was seen in 31 (55%). Nasolacrimal duct anomalies were found to be the most common (32%) followed by congenital esotropia (14%). Education, awareness, counseling about risks of consanguinity and other risk factors such as maternal age, infections, medications during pregnancy, vaccination must be a routine practice in healthcare set up. This can significantly reduce morbidity and prevent blindness.
Dimensional stability and surface hardness of inter-occlusal recording materials
Authors:   Department of Prosthodontics Crown and Bridge, Maharaja Ganga Singh Dental College and Research Centre, Sri Ganganagar, Rajasthan, India, Gosai Khyati N , Patel Ina B ,   Department of Prosthodontics Crown and Bridge, AMC Dental College and Hospital, Ahmedabad, Gujarat, India, Poonia Pooja ,   Department of Prosthodontics Crown and Bridge, Ahmedabad Dental College, Ahmedabad, Gujarat, India, Sutaria Bhagyashree ,   Department of Prosthodontics Crown and Bridge, Siddhpur Dental College and Hospital, Gujarat, India, Trivedi Mahima ,   Dental Studio, Vadodara, Gujarat, India, Mori Sarita ,   Department of Periodontology, Ahmedabad Dental College, Ahmedabad, Gujarat, India
Published: May 2024

It is important to choose the appropriate interocclusal registration material for precise articulation and successful dental prosthesis fabrication. 3 types of interocclusal registration materials: Bite registration wax, polyvinyl siloxane bite registration paste and Bisacryl-based bite registration paste were evaluated for dimensional stability and surface hardness at 4 different time intervals. One way ANOVA test, multiple Post Hoc Tukey HSD test and nonparametric test were performed. Bisacryl-based bite registration material exhibited better dimensional stability and surface hardness than polyvinyl siloxane and bite registration wax at all 4 time intervals. Thus dimensional stability and surface hardness of interocclusal registration material was influenced by both the type of material and the time duration.
Linking IL-6 and hsCRP among Indian patients with myocardial infarction
Authors:   Department of Medicine, Rajarshi Dashrath Autonomous State Medical College, Ayodhya, India, Verma Virendra , Sharma Pavan Kumar ,   Department of Biochemistry, Rama Medical College Hospital & Research Centre, Kanpur, India, Singh Shashi Prabha ,   Department of Biochemistry, Maa Vindhyavasini Autonomous State Medical College, Mirzapur, India, Sarmah Devajit ,   Department of Biochemistry, Rajarshi Dashrath Autonomous State Medical College, Ayodhya, India, Patel Rajni ,   Department of Anatomy, Autonomous State Medical College, Etah, India, Verma Poonam ,   President, Society for Scientific Research, Barabanki, India, Tripathi Shiv Shanker ,   Department of Emergency Medicine, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India, Arya Deepa ,   Department of Biochemistry, Rama Medical College Hospital & Research Centre, Kanpur, India, Verma Manish Kumar ,   Department of Biochemistry, Rajarshi Dashrath Autonomous State Medical College, Ayodhya, India
Published: May 2024

The association between serum interleukin-6 (IL-6) and highly sensitive C - reactive protein (hsCRP) as predictors of the risk factors for Myocardial Infarction. The study included a total of 50 patients with Myocardial Infarction, aged between 25 to 74 years. The levels of hsCRP were measured using the immunoturbidimetry method, while Interleukin 6 was estimated using the sandwich ELISA method. Statistical analysis was conducted using SPSS version 21.0, with p values calculated using Quartile ratio, ANOVA unpaired t-test, and Kaplan-Meier Curve Method. A p-value of less than 0.05 was considered statistically significant. All participants underwent a questionnaire, physical examination, medical history assessment, and laboratory tests. The results of the study showed that there was a significant correlation between IL-6 and hsCRP levels in the Quartile groups, as well as with lipid profiles. The Kaplan-Meier method also demonstrated a significant association between IL-6 and hsCRP levels in participants. The comparison of biomarkers further supported these findings. Thus, data shows that elevated levels of hsCRP and IL-6 could serve as valuable diagnostic markers for predicting Acute Myocardial Infarction. Our study strongly suggests that IL-6 could be a powerful marker in evaluating the Myocardial Infarction.
Efficacy of pregabalin, amitriptyline, and gabapentin for neuropathic pain
Authors:   GMERS Medical College, Himmatnagar, Gujarat , India, Trived Prachi Dilipkumar , Posani Sarojini ,   Dr. Parveen Multi-speciality Clinic, Kothagudem, India, Balla Neeharika ,   Maharajah's Institute of Medical Sciences, Vizianagaram, India, Sheezan Mohommed Mujtaba ,   Medical University of Lodz , Poland, Hussain Ayesha Salim ,   Medical Officer, Ziva hospital, Kharar, Chandigarh, India, Xavier Roshni ,   Medical Officer at Carewell Hospital, Padapparamba, Malappuram, Kerala , India, Popatbhai Kachhadia Meet ,   P.D.U Medical College, Civil hospital campus, Rajkot, Gujarat, India, Mateen Mohammed Abdul ,   Shadan Institute of Medical Sciences Teaching hospital and Research Centre, Hyderabad, India, Prajjwal Priyadarshi ,   Neurology, Bharati Vidyapeeth University Medical College, Pune, India, Marsool Marsool Mohammed Dheyaa ,   University of Baghdad/Al-Kindy College of Medicine, Baghdad, Iraq
Published: May 2024

Neuropathic pain largely influences the well-being of patients. Anticonvulsant and antidepressant medications, such as Pregabalin, Gabapentin, and Amitriptyline, are routinely prescribed as initial treatments for neuropathic pain. The study sample has a total of 270 patients who meet the inclusion criteria and are further distributed into three equally sized groups (A, B, and C). Group A was administered with Gabapentine 300mg, Group B with Pregabalin 75 mg, and Amitriptyline 10 mg to Group C. The occurrence of any adverse drug response was documented using the ADR reporting form, while the pain of the patient's post-medication was recorded using a numerical pain rating scale (NPRS). The comparison of the NPRS scores of all three groups "by using ANOVA test" both at baseline and after 15 days reveal that the differences between the three groups are statistically insignificant (p > 0.089). However, after one month of continuous use, the difference becomes slightly significant (I.e., p = 0.003). Gabapentin, pregabalin, and amitriptyline demonstrate similar effectiveness in alleviating neuropathic (NeP) pain. The study concludes that gabapentin is superior to both pregabalin and amitriptyline with fewer adverse effects, leading to improved patient adherence for long-term use.
Measurement of mandibular incisive canal diameter using cone beam computed tomography
Authors:   Department of Oral Medicine and Radiology, Narshinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India, Anand Prachi , Mehta Dhaval N ,   Department of Oral Medicine and Radiology, Narshinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India, Kumar Dewanshu ,   Department of Prosthodontics Crown and Bridge, Maharana Pratap Dental College and Hospital, Kanpur, Uttar Pradesh, India, Thakur Richa ,   Department of Oral Medicine and Radiology, Dental College of Azamgarh, Purvanchal University, Azamgarh, Uttar Pradesh, India, Malviya Rohit ,   Department of Prosthodontics Crown and Bridge Career Post Graduate Institute of Dental Sciences, Dr.Ram Manohar Lohia Avadh University, Ayodhya, Uttar Pradesh, India, Kumar Rohit ,   Department of Oral medicine and Radiology, Bhabha college of dental sciences, Bhabha University, Bhopal, Madhya Pradesh, India
Published: May 2024

Cone beam computed tomography was used for measuring the diameter of a Mandibular incisive canal. The dental practice can now visualize small bone structures with low dose and high spatial resolution due to the introduction of CBCT (Cone Beam Computed Tomography). Therefore, it is of interest to measure the diameter of the MIC (Mandibular Incisive Canal) using the CBCT. Fifty CBCT scans obtained for implant placement preoperative planning were included in the study material. Observers carefully examined the CBCT data to determine the MIC’s presence & position. The inner diameter of the MIC was measured by taking the longest distance between the inner cortical borders of the canal which was further analyzed using software CS3D software. The collected data were further subjected to statistical analysis. The average mean of the population was 1.7130±.5178. The average diameter of MIC in males was 1.735±.5406 and in females was 1.6800±.4934. Complications from implant surgery in the anterior mandible may be prevented by utilizing CBCT scans to analyze the smallest diameter of the MIC.
Screening, awareness and challenges for colorectal cancer treatment in Saudi Arabia: an update
Authors:   Department of Biological Science, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Hassan Alqarni Samer Mohammed , Alamri Mohammed Saad ,   Department of Biological Science, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Pushparaj Peter Natesan ,   Center of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Rather Irfan ,   Department of Biological Science, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Lqbal Zafar ,   King Saud Bin Abdul Aziz University, King Abdullah International Medical Research Center, Al Ahsa, Saudi Arabia, Asif Muhammad ,   Department of Biotechnology, & ORIC, Balochistan University of Information Technology, Engineering & Management Sciences, Quetta, Pakistan, Rasool Mahmood ,   Center of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
Published: May 2024

Colorectal cancer (CRC) is the second most common cancer in the world. In Saudi Arabia, CRC is the most common cancer in males and the third most common in females, and its incidence rate is rising as the country continues to develop. However, the country does not have a national CRC screening program for CRC. This review aims to review recent studies that have attempted to address and rectify this issue and discern the most notable and prevalent barriers. Despite these efforts, guidelines are still lacking. Two prospective studies have been conducted in recent years, one of which was a national pilot screening program conducted by the Ministry of Health (MOH). While both had a similar number of participants, the colonoscopy rate for patients with a positive fecal immunochemical test (FIT) in the MOH program was only 20% compared to 75.8% in the Al-Kharj program. Awareness of the Saudi population regarding CRC and its screening appears to be insufficient. The most common barriers to patients' willingness to undergo screening were embarrassment, fear, and pain. Barriers to physicians are mostly related to factors outside their hands, such as lack of equipment and time. We conclude that efforts should be made to establish a national screening program and improve awareness of the population and physicians.
Filosofi Pendidikan Yang diusung Oleh Ki Hadjar Dewantara dan Evolusi Pendidikan di Indonesia
Authors: Tia Basana Hutagalung  , Liesna Andriany
Published: May 2024

The foundation of education is a universal human aspiration; therefore, in addressing educational issues, complex solutions with philosophical foundations are necessary to ensure that the resulting solutions benefit all segments of society. One of the figures with strong philosophical views on education is Ki Hadjar Dewantara. Ki Hadjar Dewantara, a nobleman from the Yogyakarta Sultanate, firmly held a high concern for the development of education. The philosophical views put forward by Ki Hadjar Dewantara have become the basis for educational development in Indonesia. Ki Hadjar Dewantara expressed that the essence of education is an effort to internalize cultural values ​​into the souls of children with the aim of shaping them into complete human beings, both spiritually and mentally. This educational philosophy is known as the "Sistem Among," which emphasizes the basic ability of children to overcome the problems they face by providing them with broad freedom of thought. Ki Hadjar Dewantara formulated his philosophy by applying indigenous Indonesian culture, selectively adopting Western values ​​to fit the trikonic theory, and then adapting them wisely. Ki Hadjar Dewantara also made several contributions to Indonesian education, including the implementation of the leadership trilogy in education, the three educational centers, and the paguron system. Education is an effort to develop the human potential of learners, both physically, intellectually, emotionally, and morally, so that this potential can be realized and beneficial to their lives.
DOMINÓ DAS EQUAÇÕES: RECURSO LÚDICO PARA O APRENDIZADO DA ÁLGEBRA EM UMA ESCOLA PÚBLICA DA CIDADE DE PARAÍSO DO TOCANTINS-TO
Authors: De Castro da Silva Kênia , De Freitas Cruz Rayanne , Melo Viroli Sérgio Luis
Published: May 2024

Álgebra é um conteúdo matemático que exige um intenso nível de abstração, devido aos valores numéricos expressos na forma literal, ou seja, uso de letras para expressar valores numéricos, podendo não apresentando significado para a maioria dos alunos, situação, que pode provocar uma considerável queda do aprendizado, iniciando uma incompreensão dos conteúdos matemáticos escolares. Diante do contexto, a pesquisa teve como objetivo utilizar e avaliar o jogo dominó das equações do 1º grau para auxiliar o processo de ensino-aprendizagem em sala de aula. O estudo foi desenvolvido de forma quantitativa, visando avaliar um jogo desenvolvido para auxiliar a aprendizagem de equações do 1º grau. O jogo foi aplicado no mês de agosto, em uma turma com 40 alunos do 1º ano do Ensino Médio, no período matutino, com duração de 50 minutos, em uma escola pública localizada na cidade de Paraíso do Tocantins, Estado do Tocantins. Após a utilização do jogo, os alunos foram convidados a responder um questionário com as seguintes 3 (três) questões fechadas e 2 (duas) abertas. O diagnóstico A análise da aplicação do jogo Dominó das equações do 1º grau, demostra que a abordagem lúdica realizada apresentou valores iguais ou superiores a 70% em todos os quesitos questionados, evidenciando boa aceitação e contribuindo para um aprendizado significativo sobre o conteúdo de álgebra estudado. O jogo dominó das equações do 1º grau proporcionou uma situação de socialização em ambiente descontraído e interativo, gerando uma aprendizagem contextualizada e mais próxima do cotidiano do aluno. Portanto, o uso da atividade lúdica foi uma estratégia auxiliar de grande relevância para o aprendizado e fixação do estudo da álgebra e operações matemáticas básicas, apoiando o professor a contextualizar o conteúdo e motivar os alunos.
An Innovative Approach on Yao’s Three-Way Decision Model Using Intuitionistic Fuzzy Sets for Medical Diagnosis
Authors: Ali Wajid , Shaheen Tanzeela , Haq Iftikhar Ul , Smarandache Florentin , Toor Hamza Ghazanfar , Asif Faiza
Published: May 2024

In the realm of medical diagnosis, intuitionistic fuzzy data serves as a valuable tool for representing information that is uncertain and imprecise. Nevertheless, decision-making based on this kind of knowledge can be quite challenging due to the inherent vagueness of the data. To address this issue, we employ power aggregation operators, which prove effective in combining several sources of data, such as expert thoughts and patient information. This allows for a more correct diagnosis; a particularly crucial aspect of medical practice where precise and timely diagnoses can significantly impact medication policy and patient results. In our research, we introduce a novel methodology to the three-way decision idea. Initially, we revamp the three-way decision model using rough set theory and incorporate interval-valued classes to handle intuitionistic fuzzy data. Secondly, we explore the use of intuitionistic fuzzy power weighted and intuitionistic fuzzy power weighted geometric aggregation operators to consolidate attribute values within the data system. Furthermore, we present a case study in the medical field to exhibit the validity and efficiency of our offered technique. This innovative method enables us to classify participants into three distinct zones based on their symptoms. The manuscript concludes with a summary of key points provided by the authors.
Exploring Factors Influencing Trust in Banks: A Multifaceted Analysis
Authors: Sanneh Tumani , Qamar Ayesha , Muzamir Mafabi
Published: May 2024

The intricate dynamics of trust formation within financial institutions, particularly in the banking sector, are explored in this research, combined with an exploration of the influence of attitudes and sociodemographic factors. Employing an ordered-logistic regression model on a different sample, we scrutinized the nexus between individuals' trust in banks and various factors such as age, educational attainment, technological proficiency, religious affiliations, marital status, income level, and family size. Our findings reveal several significant correlations: technological proficiency, age, and education all boost individuals' confidence in banks, whereas religious beliefs exhibit a negative relationship. Conversely, we have noted that the total number of children in a family, income level, and marital status exert adverse effects on trust in banking institutions. These discoveries underscore the complex interplay between personal attributes and attitudes in shaping perceptions of the trustworthiness of financial organizations. Policymakers and banking professionals must comprehend these dynamics to foster trust and stability within the banking sector.
The Effectiveness of an Interactive Video-Based Program in Developing the Skills of Comparing and Ordering Numbers Among Individuals with Hearing Disabilities
Authors: Albalhareth Ali Hamad , Saleem Suhib Saleem
Published: May 2024

The aim of the current research is to enhance the skills of comparing and ordering numbers through the utilization of interactive videos among students with hearing disabilities, including those who are hearing impaired or deaf. Employing a quasi-experimental design, the study adopts a one-group pretest-posttest approach, involving (12) students who received instruction through interactive videos. Initially, pretest measures were administered, followed by the experimental intervention, and subsequently, posttest evaluations of comparing and ordering number skills were conducted. The study employed specific tools, including a test assessing comparing and ordering numbers skills, as well as an interactive video program. The findings of the study underscore the efficacy of the interactive video-based training program in fostering the development of comparing and ordering number skills among the sampled individuals. Moreover, the research revealed no statistically significant disparities, at a significance level of 0.05, in the posttest scores among students, attributed to variations in the severity of their disabilities. Furthermore, no statistically significant differences were observed, at the same significance level, between the posttest scores and those obtained during the follow-up assessment, indicating the sustained effectiveness of the program over time. In conclusion, the study culminates in a series of recommendations and proposed avenues for further research in this domain.
Regulation of mitochondrial function by FOXOs in ischemic stroke and Alzheimer’s disease
Authors: Asadi Yasin , Wang Hongmin
Published: May 2024

Transcriptional control is a pivotal mechanism governing various cellular processes. FOXO proteins, a subgroup of the forkhead family of transcription factors, play a key role in determining cell fate. The localization and function of FOXO proteins are regulated by post-translational modifications to control target gene expression, with a pronounced impact on various aspects of mitochondrial function, including mitochondrial dynamics, biogenesis, and quality control. Mitochondria stand out as the primary target of FOXO transcription factors, which recruit downstream signaling factors to govern mitochondrial processes. Essential signaling pathways are modulated by FOXOs, exemplified by their regulation of mitochondrial biogenesis through SIRT1-Pgc1a and NRF1-TFAM, as well as their influence on mitochondrial dynamics involving Mfn1, Mfn2, Drp1, and Fis1. Furthermore, FOXOs demonstrate the ability to upregulate and downregulate genes that serve as modulators in oxidative and apoptosis cascades. The functional role of FOXO proteins is highly context-dependent, varying with cell type, organ, and specific FOXO isoform. Notably, FOXOs emerge as prominent players in various pathological conditions, including ischemic conditions, neurodegenerative diseases, cancer, and metabolic disorders. Unraveling the complex role of FOXOs in mammalian cell pathology positions them as promising therapeutic targets receptive to pharmacological treatment. This review aims to provide insights into the intricate roles of FOXOs in mitochondria, illuminating their potential as therapeutic targets amenable to pharmacological intervention in diverse pathological contexts, particularly in ischemic stroke and Alzheimer’s disease.
SUPPRESSION OF EPILEPTIC ACTIVITY IN RABBITS THROUGH SEROTONIN-MODULATING ANTICONSOLIDATION PROTEIN
Authors: Panahova E.N. , Allahverdiyeva A.M. , Mekhdiyeva A.A. , Mekhtiev A.A.
Published: May 2024

The article concerns molecular basis of epileptic seizures development and elaboration of novel ways of their suppression through upregulation of serotonergic system activity on subcellular level by administration of serotonin-modulating anticonsolidation protein (SMAP). This protein had been purified earlier from the rat brains, possesses with Mr 186 kDa and is being in linear relationship with serotonin. Epileptic seizures were formed in Shinshilla rabbits by microapplication of 300 units of sodium penicillin solution into the brain amygdala. The evoked potentials (EP) to light flashes were fixed in the visual cortex, colliculus superior and retina. The epileptic seizures reached their peak for 50 min and lasted for 3 h. During their development, strengthening of the EP in the form of increasing their positive components, advent of interictal spikes and visually myoclonical seizures was observed. Administration of SMAP (3.5 ml, 1.5 mg/ml, i.m.) to rabbits 30 min after induction of epileptic seizures led to their suppression and elimination of their all manifestations including interictal spikes. The conclusion is done that upregulation of SMAP leads to suppression of epileptic seizures.