bluuebunny/crossref_metadata_2025 huggingface dataset:
Panax notoginseng Saponins Promote Cell Death and Chemosensitivity in Pancreatic Cancer through the Apoptosis and Autophagy Pathways
Authors: Yao Li-Chao , Wu Lun , Wang Wei , Zhai Lu-Lu , Ye Lin , Xiang Feng , Tang Zhi-Gang
Published: November 2020

Background:

Panax notoginseng Saponins (PNS) is used as a traditional Chinese medicine for
ischemic stroke and cardiovascular disease; it has been proven to possess anticancer activity recently.

Objective:

In this study, we aimed to explore the curative anticancer effect and potential mechanisms of PNS in
pancreatic cancer cells.

Methods:

Pancreatic cancer Miapaca2 and PANC-1 cells were treated with PNS and Gemcitabine (Gem), respectively. Then the cell
viability was assessed by CCK-8 assay, cell proliferation was tested by colony formation assay and EdU cell proliferation assay, cell
migration and invasiveness were tested by wound healing assay and transwell assay respectively, and cell apoptosis was detected by flow
cytometry. Finally, we detected the expression levels of proteins related to migration, apoptosis and autophagy through Western blotting.

Results:

PNS not only inhibited the proliferation, migration, invasion and autophagy of Miapaca2 and PANC-1
cells, but also induced apoptosis and promoted chemosensitivity of pancreatic cancer cells to Gem.

Conclusion:

PNS may exhibit cytotoxicity and increase chemosensitivity of pancreatic cancer cells to Gem by
inhibiting autophagy and inducing apoptosis, providing a new strategy and potential treatment option for
pancreatic cancer.
Implementasi pendidikan karakter melalui pembelajaran pendidikan Pancasila dan kewarganegaraan di sekolah berbasis pesantren
Authors: Lestari Yuni Niki , Marzuki Marzuki
Published: November 2020

The purposes of this research are to describe the implementation of character education, identifying the affected factors and to analyze the right solution to solve the problem in the implementation of character education through the learning process of Civic and Pancasila Education for the students of Islamic boarding (pesantren) based school. This research is a descriptive qualitative research. The selection of the research subject is used by purposive technique. The data collection of the research is used by non-participant observation, interview and documentation. The validity of the research is used by triangulation. The data analysis process is based on the interactive model proposed by Miles and Huberman which include the data reduction, data display and drawing conclusion. The results showed that; (1) The implementation of character education through the learning process of Civic and Pancasila Education is through three phases namely plan, action and evaluation; (2) The supporting factors for character education include the boarding school environment of the islamic boarding school, the majority of teachers are alumni of the Islamic boarding school, and scout extracurriculer activity, while the inhibiting factors include the different characteristics of the santri, the distance between the santri male dormitory and the madrasah which is so far that the teacher cannot communicate directly, and the learning duration is small; (3) the possible solutions that will optimalize the learning results are the point system; when the students breaking the rules is 25 points as a warning and 50 points to reprimand the students, and the coordination and cooperation between madrasah and the boarding house.
Pendidikan lingkungan berbasis experiential learning untuk meningkatkan literasi lingkungan
Authors: Hayati Riza Sativani
Published: November 2020

Damage to the ecosystem and decline in the amount of biodiversity continues. Ecosystem damage due to human activities has become a global problem. This destructive activity reflects the low of the community’s environmental literacy. Environmental education can be a solution to improve community’s environmental literacy. The objectives of environmental education are (1) awareness; (2) knowledge; (3) attitude; (4) skills; and (5) participation. One effective method in environmental education is based on experiential learning. This article aims to explain the concept of environmental education based on experiential learning which can be an alternative integration of environmental education in schools. This article discusses the urgency of environmental literacy, how environmental education can improve environmental literacy, and detailed concepts of how to implement environmental education based on experiential learning in schools. Experiential learning-based environmental education means instilling Kolb’s learning cycle in learning and environmental education programs. The Kolb cycle consists of: (1) Concrete Experience; (2) Observation and Reflection; (3) Forming Abstract Concept; (4) Testing in New Situation. Experiential learning based environmental education will provide provisions for students to be able to design pro-environment actions or participate in providing solutions to environmental problems.
Pemanfaatan media pembelajaran dalam meningkatkan motivasi dan hasil belajar PAI di sekolah dan madrasah
Authors: Sartika Fitria , Desriwita Elni , Ritonga Mahyudin
Published: November 2020

This study discusses the use of instructional media in increasing motivation and learning outcomes of Islamic Religious Education in Schools and Madrasas. Learning media is an important thing used by teachers to attract interest and foster student motivation in learning, especially Islamic religious subjects, so that students easily understand the material presented without feeling bored and tired of listening to the teacher's submission. With the aim that PAI learning materials can really be understood and practiced by students after being studied at school and madrasa. The method used in this research is a quantitative qualitative approach that is described descriptively. The findings state that the Rasulullāh sebagai as an excellent educator has also used various forms of media in conveying Islamic education to friends, so that friends are able to understand the teachings of Islam properly and correctly. The results of the study of the use of instructional media show that learning media can provide an increase in student motivation, greatly assisting teachers in implementing the teaching and learning process to achieve the objectives of a learning material. The use of instructional media is also able to provide a great influence in improving student learning outcomes in PAI learning in schools and madrasas.
Model manajemen Madrasah Aliyah Pembangunan Universitas Islam Negeri (UIN) Jakarta
Authors: Achmad Widodo Syukri Fathudin , Sudrajat Ajat , Sugiyono Sugiyono
Published: November 2020

The article aims to see the Management Model of Madrasah Aliyah Laboratorium from the aspects of planning, organizing, implementing, and monitoring. At Madrasah Aliyah Pembangunan (MAP) UIN Jakarta. The research method used is qualitative. The results showed the Madrasah Aliyah Laboratory management model consists of the first three components: the organizational structure of the Madrasah Aliyah Laboratory, including management (Director) and Madrasah Implementer (Madrasah Head), the second existing culture (culture). in Madrasah Aliyah Laboratory including academic and non-academic including custom curriculum, reading habits, English-Arabic days and the three figures who play a role in Madrasah Aliyah Laboratorium, both head of a madrasah, teachers, and madrasah committee
A Relationship between Theory of Mind and Pragmatic Language in Adolescents with Mild Intellectual Disabilities
Authors: Cheon Jeongmin , Kim Whasoo
Published: November 2020

Purpose: The purpose of this study was to investigate the characteristics of pragmatic language ability, which is known to be closely related to the performance level of mind-reading ability of adolescents with mild intellectual disabilities, the theory of mind, and the relationship among them.Methods: A total of 40 (20 adolescents with mild intellectual disabilities aged 19-21 years; 20 children with language age-matched) participated in this study. Mind-reading ability and pragmatic language ability of adolescents with mild intellectual disability and those of children with language age-matched were evaluated and compared.Results: The adolescents with mild intellectual disabilities showed significantly lower performance in mind-reading ability and pragmatic language ability when compared to the control group. Among subtasks of pragmatic language ability, only nonverbal communication was positively correlated with faux pas of mind-reading ability.Conclusion: The present study suggests that mind-reading ability can be related to pragmatic language ability in adolescents with mild intellectual disabilities. We believe that current findings support to understand essential Knowledge required to develop and establish language intervention and communication-related assessment tools that encompass the mind-reading ability of adolescents with mild intellectual disabilities.
A Study on the Media Literacy Through an Analysis on SNS Writing Errors of Adults with Mild Intellectual Disabilities
Authors: Lim Soyeon , Kim Whasoo
Published: November 2020

Purpose: The purpose of this preliminary research attempted for media literacy from a linguistic perspective was to analyze writing errors in social network service (SNS) usage on adults with mild intellectual disabilities and to use it as preliminary data of writing education using media such as SNS.Methods: A total of 30 peoples (15 for adults with mild intellectual disabilities and 15 for general adults) participated. Data were extracted writing errors in SNS usage at random and analyzed them qualitatively and quantitatively.Results: The qualitative analysis showed that total score of adults with mild intellectual disability was lower than that of the general adults while there was same pattern in all 5 subcategories . In the quantitative analysis, there was a significant difference in the use of postposition between two groups. Also, both groups showed a positive correlation among three subcategories such as spelling, word spacing, and postposition.Conclusion: This study have significance in conducting an analysis on spontaneity of adults with mild intellectual disabilities that appears on SNS that was not sufficiently attempted previously and this researcher expects the analysis result to be used as a preliminary data of developing writing-related education using media such as SNS.
Development and Validation of an Automated Algorithm to Detect Atrial Fibrillation Within Stored Intensive Care Unit Continuous Electrocardiographic Data: Observational Study
Authors: Walkey Allan J , Bashar Syed K , Hossain Md Billal , Ding Eric , Albuquerque Daniella , Winter Michael , Chon Ki H , McManus David D
Published: November 2020

Background

Atrial fibrillation (AF) is the most common arrhythmia during critical illness, representing a sepsis-defining cardiac dysfunction associated with adverse outcomes. Large burdens of premature beats and noisy signal during sepsis may pose unique challenges to automated AF detection.

Objective

The objective of this study is to develop and validate an automated algorithm to accurately identify AF within electronic health care data among critically ill patients with sepsis.

Methods

This is a retrospective cohort study of patients hospitalized with sepsis identified from Medical Information Mart for Intensive Care (MIMIC III) electronic health data with linked electrocardiographic (ECG) telemetry waveforms. Within 3 separate cohorts of 50 patients, we iteratively developed and validated an automated algorithm that identifies ECG signals, removes noise, and identifies irregular rhythm and premature beats in order to identify AF. We compared the automated algorithm to current methods of AF identification in large databases, including ICD-9 (International Classification of Diseases, 9th edition) codes and hourly nurse annotation of heart rhythm. Methods of AF identification were tested against gold-standard manual ECG review.

Results

AF detection algorithms that did not differentiate AF from premature atrial and ventricular beats performed modestly, with 76% (95% CI 61%-87%) accuracy. Performance improved (P=.02) with the addition of premature beat detection (validation set accuracy: 94% [95% CI 83%-99%]). Median time between automated and manual detection of AF onset was 30 minutes (25th-75th percentile 0-208 minutes). The accuracy of ICD-9 codes (68%; P=.002 vs automated algorithm) and nurse charting (80%; P=.02 vs algorithm) was lower than that of the automated algorithm.

Conclusions

An automated algorithm using telemetry ECG data can feasibly and accurately detect AF among critically ill patients with sepsis, and represents an improvement in AF detection within large databases.
Physiotherapists’ Use of Web-Based Information Resources to Fulfill Their Information Needs During a Theoretical Examination: Randomized Crossover Trial
Authors: Doherty Cailbhe , Joorabchi Arash , Megyesi Peter , Flynn Aileen , Caulfield Brian
Published: November 2020

Background

The widespread availability of internet-connected smart devices in the health care setting has the potential to improve the delivery of research evidence to the care pathway and fulfill health care professionals’ information needs.

Objective

This study aims to evaluate the frequency with which physiotherapists experience information needs, the capacity of digital information resources to fulfill these needs, and the specific types of resources they use to do so.

Methods

A total of 38 participants (all practicing physiotherapists; 19 females, 19 males) were randomly assigned to complete three 20-question multiple-choice questionnaire (MCQ) examinations under 3 conditions in a randomized crossover study design: assisted by a web browser, assisted by a federated search portal system, and unassisted. MCQ scores, times, and frequencies of information needs were recorded for overall examination-level and individual question-level analyses. Generalized estimating equations were used to assess differences between conditions for the primary outcomes. A log file analysis was conducted to evaluate participants’ web search and retrieval behaviors.

Results

Participants experienced an information need in 55.59% (845/1520) MCQs (assisted conditions only) and exhibited a mean improvement of 10% and 16% in overall examination scores for the federated search and web browser conditions, respectively, compared with the unassisted condition (P<.001). In the web browser condition, Google was the most popular resource and the only search engine used, accounting for 1273 (64%) of hits, followed by PubMed (195 hits; 10% of total). In the federated search condition, Wikipedia and PubMed were the most popular resources with 1518 (46% of total) and 1273 (39% of total) hits, respectively.

Conclusions

In agreement with the findings of previous research studies among medical physicians, the results of this study demonstrate that physiotherapists frequently experience information needs. This study provides new insights into the preferred digital information resources used by physiotherapists to fulfill these needs. Future research should clarify the implications of physiotherapists’ apparent high reliance on Google, whether these results reflect the authentic clinical environment, and whether fulfilling clinical information needs alters practice behaviors or improves patient outcomes.
Evaluating Behavioral and Linguistic Changes During Drug Treatment for Depression Using Tweets in Spanish: Pairwise Comparison Study
Authors: Leis Angela , Ronzano Francesco , Mayer Miguel Angel , Furlong Laura I , Sanz Ferran
Published: November 2020

Background

Depressive disorders are the most common mental illnesses, and they constitute the leading cause of disability worldwide. Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed drugs for the treatment of depressive disorders. Some people share information about their experiences with antidepressants on social media platforms such as Twitter. Analysis of the messages posted by Twitter users under SSRI treatment can yield useful information on how these antidepressants affect users’ behavior.

Objective

This study aims to compare the behavioral and linguistic characteristics of the tweets posted while users were likely to be under SSRI treatment, in comparison to the tweets posted by the same users when they were less likely to be taking this medication.

Methods

In the first step, the timelines of Twitter users mentioning SSRI antidepressants in their tweets were selected using a list of 128 generic and brand names of SSRIs. In the second step, two datasets of tweets were created, the in-treatment dataset (made up of the tweets posted throughout the 30 days after mentioning an SSRI) and the unknown-treatment dataset (made up of tweets posted more than 90 days before or more than 90 days after any tweet mentioning an SSRI). For each user, the changes in behavioral and linguistic features between the tweets classified in these two datasets were analyzed. 186 users and their timelines with 668,842 tweets were finally included in the study.

Results

The number of tweets generated per day by the users when they were in treatment was higher than it was when they were in the unknown-treatment period (P=.001). When the users were in treatment, the mean percentage of tweets posted during the daytime (from 8 AM to midnight) increased in comparison to the unknown-treatment period (P=.002). The number of characters and words per tweet was higher when the users were in treatment (P=.03 and P=.02, respectively). Regarding linguistic features, the percentage of pronouns that were first-person singular was higher when users were in treatment (P=.008).

Conclusions

Behavioral and linguistic changes have been detected when users with depression are taking antidepressant medication. These features can provide interesting insights for monitoring the evolution of this disease, as well as offering additional information related to treatment adherence. This information may be especially useful in patients who are receiving long-term treatments such as people suffering from depression.
Preliminares (a unas Teoría/S "archipiélicas")
Authors: Vauthier Bénédicte
Published: November 2020

Abstract
Para una historia del relato de viaje hispánico (siglos XIX-XXI): noticia de una investigación en marcha
Authors: Peñate Rivero Julio
Published: November 2020

El autor del ensayo empieza destacando la extraordinaria presencia de la narrativa de viaje en la literatura occidental y sus conexiones con  otras disciplinas literarias y humanísticas (autobiografía, autoficción, etnografía, etc.). A continuación, tras abordar el estado de la cuestión en torno al relato factual de los dos últimos siglos, se refiere a sus propias investigaciones en este campo insistiendo en la metodología del análisis textual y en la función peculiar de elementos discursivos como la ficcionalidad, la descripción y la digresión. Finalmente, presenta una etapa capital en la historia de la narrativa viática española, la del siglo xix, ilustrándola con  las variantes del relato africanista, tan escasamente conocido hasta hoy.
Voltage-gated calcium channels (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database
Authors: Catterall William A. , Perez-Reyes Edward , Snutch Terrance P. , Striessnig Jörg
Published: November 2020

Calcium (Ca2+) channels are voltage-gated ion channels present in the membrane of most excitable cells. The nomenclature for Ca2+channels was proposed by [120] and approved by the NC-IUPHAR Subcommittee on Ca2+ channels [68]. Ca2+ channels form hetero-oligomeric complexes. The α1 subunit is pore-forming and provides the binding site(s) for practically all agonists and antagonists. The 10 cloned α1-subunits can be grouped into three families: (1) the high-voltage activated dihydropyridine-sensitive (L-type, CaV1.x) channels; (2) the high-voltage activated dihydropyridine-insensitive (CaV2.x) channels and (3) the low-voltage-activated (T-type, CaV3.x) channels. Each α1 subunit has four homologous repeats (I-IV), each repeat having six transmembrane domains and a pore-forming region between transmembrane domains S5 and S6. Voltage-dependent gating is driven by the membrane spanning S4 segment, which contains highly conserved positive charges that respond to changes in membrane potential. Many of the α1-subunit genes give rise to alternatively spliced products. At least for high-voltage activated channels, it is likely that native channels comprise co-assemblies of α1, β and α2-δ subunits. The γ subunits have not been proven to associate with channels other than the α1s skeletal muscle Cav1.1 channel. The α2-δ1 and α2-δ2 subunits bind gabapentin and pregabalin.
Reseña: La empresa en el siglo XXI. Un estudio multidisciplinar de carácter jurídico empresarial. Eduardo Carlos Dittmar (2019)
Authors: Vargas Portillo Patricia
Published: November 2020

Eduardo Carlos Dittmar es vicedecano de investigación de EAE Business School, así como editor de la revista Harvard Deusto Business Research. Su investigación presenta carácter interdisciplinar, pudiendo calificarse de frontera entre las ciencias empresariales y el mundo jurídico. Una formación jurídica que supere la perspectiva meramente normativa e incluya otras dimensiones —como, entre otras, la económica, empresarial, política, histórica, sociológica o filosófica— suministraría al operador jurídico diferentes instrumentos que le darían la oportunidad de comprender, con una mayor amplitud, los fenómenos sociales y aplicar las normas respecto a la realidad social.
Polimedicação e doenças crônicas apresentadas por idosos de uma instituição de longa permanência
Authors: Cecchin Luana , Lima Alisson Padilha de , Tomicki Camila , Portella Marilene Rodrigues
Published: November 2020

Introdução: Os efeitos prejudiciais envolvendo medicamentos pela população idosa impulsionam pesquisas para desenvolvimento e aplicação de diversos métodos e instrumentos para identificar padrões inadequados de prescrição e uso. Objetivo: Avaliar a polimedicação e as doenças crônicas apresentadas por idosos de uma instituição de longa permanência. Materiais e Métodos: Estudo transversal, por meio de análise de prontuários de todos os pacientes acima de 60 anos em uma instituição de longa permanência para idosos, para a classificação dos medicamentos foi adotado os Critérios de Beers versão 2012, que classifica os medicamentos potencialmente inapropriados para idosos. Resultados: Foram avaliados 47 idosos com média de 77,68 anos com média de 6,32 medicamentos ao dia por idoso, sendo que destes 55,31% utilizavam medicamentos potencialmente inapropriados. Conclusão: Esses resultados indicam a necessidade da adoção de estratégias como a implantação de protocolos clínicos, mudanças no ensino médico e acompanhamento multiprofissional dos pacientes idosos, para evitar a automedicação e prescrição de medicamentos potencialmente inapropriados para a população idosa.
Autocuidado postural: educação em saúde com adolescentes do meio rural
Authors: Silva Márcia Regina da , Ferraz Lucimare , Marchiori Paula Marco , Braghini Cássia Cristina , Ferretti Fátima , Rech Ana Paula , Ferrazzo Jilciane Fatima
Published: November 2020

O presente estudo teve por objetivo promover o autocuidado postural aos adolescentes do meio rural, pois se percebeu a necessidade de desenvolver ações de educação em saúde com os adolescentes do meio rural sobre os aspectos posturais para que ao se apropriarem de conhecimento possam exercer o autocuidado, bem como tornar-se um multiplicador do saber em suas famílias e comunidade. Nesse artigo buscamos rever o conceito de postura corporal; a relação problema postural, dor/desconforto musculoesquelético dos trabalhadores com a postura e movimento corporal adotado durante a jornada de trabalho e resgatamos a prática de educar em saúde considerando o aspecto cultural. Trata-se de uma pesquisa-ação, desenvolvida com 65 estudantes do 7º e 8º ano de duas escolas do meio rural de um município do Oeste de Santa Catarina (SC), no primeiro semestre de 2013. A análise dos dados coletados foi realizada por meio de estatística descritiva. A pesquisa demonstrou que a maioria dos estudantes apresentou hábitos posturais inadequados, destacando a postura sentada na cadeira, a forma de carregar material escolar e de levantar objetos leves e pesados do chão, fato que evidencia a importância do desenvolvimento de atividades educativas que abordem tais questões.
Influência da cinoterapia e perfil do animal durante exercícios fisioterapêuticos na Síndrome de Smith Lemli Optiz
Authors: Menegazzo Aline Dupont , Souza Vanessa Stéfani Winck , Conceição Josilene S. , Fiório Franciane Barbieri
Published: November 2020

A cinoterapia é uma modalidade de tratamento que utiliza o cão como facilitador para a realização das atividades, promovendo a saúde física através de mecanismos básicos que incluem, a diminuição da solidão, depressão e ansiedade, aumento do estímulo para prática de exercícios, melhora da saúde social, emocional e cognitiva, além dos efeitos sobre o sistema nervoso simpático. No entanto, para a realização da atividade, o animal deve ter um perfil adequado. O estudo objetivou avaliar o efeito motivador da cinoterapia em uma criança com diagnóstico de Síndrome de Smith Lemli Optiz, bem como a influência do perfil do cão na execução dos exercícios. A pesquisa foi realizada com uma criança do sexo feminino, com idade de 4 anos de idade. O protocolo de tratamento consistiu em alongamento dos músculos isquiotibiais e abdutores de quadril, estimulação à postura ajoelhada e ajoelhada com rotação de tronco, transferência do sentado para a ortostase, a ortostase e o deambular, nos quais foi analisado o tempo de realização através de filmagem. Para a avaliação da motivação foi realizado o teste adaptado de McAuley, Duncan & Tammen (1987). Os resultados encontrados mostram que a cinoterapia teve influência positiva no tempo de realização dos exercícios e que o perfil do animal quando não é adequado à realização da cinoterapia exerce influencia negativa.
A música como auxílio no tratamento fisioterapêutico em pacientes com autismo: estudo de caso
Authors: Trindade Nelson Guilherme , Prestes Everson , Farias Nayara Correa
Published: November 2020

Introdução: A música pode ser utilizada como meio de intervenção em déficits sociais, comunicativos e cognitivos em indivíduos com autismo, promovendo muitos benefícios quando associada à fisioterapia. Objetivo: Avaliar e promover ganhos nos aspectos afetivos, cognitivo e motor. Métodos: Caracteriza-se por ser um estudo quanti-qualitativo, com uma amostra de- três crianças com autismo, com idades entre 5 a 7 anos. Foi  utilizado a avaliação diagnóstica Childhood Autism Rating Scale – (CARS), pré e pós-intervenção. Foi desenvolvido um protocolo de condutas fisioterapêuticas com auxilio da música em um período de dois meses. Resultados: Verificou-se através das observações dos vídeos e em sala de aula, evolução no aprendizado cognitivo, motor e funcional em todos os indivíduos. Segundo a pontuação CARS, não houve evolução significativa. Conclusão: Identificaram-se ganhos cognitivos, motores e de interação social no grupo estudado. Necessitando-se de um maior período de intervenção e instrumentos de avaliações diagnósticas mais precisas e sensíveis para esta população.
Postura e dor cervical e lombar em professores de uma escola pública de Guaíba/RS
Authors: Rocha Eduardo de Souza , Sant'Anna Patrícia Cilene Freitas , Karolczak Ana Paula Barcellos , Andriola André Hillebrand
Published: November 2020

Introdução: A dor nas regiões lombar e/ou cervical estão entre as maiores queixas de dor entre professores. Objetivo: Avaliar a associação entre desordens posturais e a presença de dor lombar e/ou cervical em professores de uma escola estadual de Guaíba/RS. Metodologia: Trata-se de um estudo transversal, com amostra composta por 24 docentes, de ambos os sexos, que apresentavam ou não dor na coluna vertebral. Para a coleta dos dados foi realizada uma avaliação postural e aplicado um questionário com questões referentes à idade, tempo de serviço, IMC, carga horária e intensidade da dor. Para a análise dos dados, a associação dos achados posturais e o local de dor foi obtida através do teste de qui-quadrado (p<0,05). Resultados: A média de idade foi de 45±8,85 anos, sendo a maioria do sexo feminino (62,5%). A dor mais prevalente foi na coluna cervical (33,3%), seguida de dor lombar (29,2%) e dor em ambas as regiões (20,8%). Observou-se que dos 16 pontos avaliados, houve associação entre o desalinhamento escapular e dor nas regiões cervical e lombar e entre a anteriorização da cabeça e a dor cervical. Conclusão: A alta prevalência de dor na coluna vertebral entre os participantes revela o quanto os professores estão expostos aos riscos posturais, o que favorece o surgimento de dores.
Museus de ciência e a mediação entre ciência e sociedade
Authors: Massarani Luisa
Published: November 2020

Como atores não clássicos no sistema de ciência, tecnologia e inovação (CT&I), os museus e centros de ciência têm uma posição privilegiada por conta de seu papel conciliador entre o público e a CT&I. Central na atividade cotidiana dos museus e centros de ciência é a mediação entre o público e as exposições e atividades oferecidas por essas organizações. Nesta edição de ‘JCOM América Latina’, representantes de sete museus de ciência ibero-americanos refletem sobre o papel dos mediadores em seus espaços e o tipo de formação fornecida a esses profissionais. A edição inclui, ainda, uma discussão sobre os desafios de mediadores de iniciativas itinerantes no Brasil e de voluntários científicos em um assentamento do primeiro milênio antes de Cristo na Espanha. Para arrematar a edição, trazemos uma iniciativa de divulgação das matemáticas em um bairro marginalizado no México e um ‘book review’ sobre o potencial educativo dos dioramas.
Dioramas: el desafío de renovar la mirada
Authors: Murriello Sandra
Published: November 2020

“Janelas para a natureza” es una compilación de textos de raigambre brasilera que permiten visibilizar el potencial educativo de los dioramas, representaciones tridimensionales frecuentes en museos de historia natural desde fines del siglo XIX. De manera sencilla los autores dan cuenta de diversas experiencias educativas en base a dioramas y nos permiten conocer algo de la historia de este recurso museográfico.
“SE É PERMITIDO FUGIR DIANTE DA AMEAÇA DE MORTE” LUTERO E A EPIDEMIA DA PESTE EM WITTENBERG
Authors: Wachholz Wilhelm
Published: November 2020

A morte é companheira da vida. Ela é caroneira da vida. A consciência da existência humana encontra-se no tempo e perante a morte. O reformador Martim Lutero tinha consciência da morte, que lhe foi companheira constante na vida. Este artigo tem por objetivo analisar manifestações de Lutero em meio aos surtos da peste, em particular, em Wittenberg. Após contextualização do ressurgimento e da expansão da peste a partir do século XIV, analisaremos prédicas, cartas e o principal escrito de Lutero sobre o tema, Se é permitido fugir diante da ameaça de morte (1527). Teologia e prática pastoral de Lutero fi cam evidenciadas ao se pesquisar o tema da peste em seus escritos. A saúde frágil de Lutero, a experiência da morte de pessoas próximas, por peste ou outras doenças, aguçaram a sensibilidade do reformador sobre o tema da morte, mas, especialmente, do cuidado aos enfermos: sua própria casa tornou-se, em vários momentos, um hospital.
IGREJA CATÓLICA E FÉ CRISTÃ EM TEMPOS DE CORONAVÍRUS/COVID-19
Authors: Wolff Elias
Published: November 2020

A pandemia do novo coronavírus/Covid-19 leva a humanidade a repensar o sentido e a forma de viver e de conviver. Questionam-se os critérios utilizados para a organização da vida pessoal e coletiva e propõe-se uma reinvenção da humanidade. É comum a afirmação de que “depois da pandemia, nada será como antes!”. Será? Este estudo tem como objetivo verificar em que medida o atual contexto de mudanças diz respeito também à igreja, aqui considerada na tradição católico-romana no Brasil. Analisa como, durante a pandemia, a igreja enfrenta o desafio por mudanças na forma de realizar a missão e de celebrar a fé; identifica os principais âmbitos dessas mudanças e analisa sua eficácia para o acompanhamento dos fiéis durante a pandemia. Finalmente, levanta a questão se tais mudanças apontam para uma reinvenção da igreja para os tempos pós-pandêmicos, pari passu com a reinvenção da humanidade.
Industry effects in directors’ dealings and abnormal stock returns: Results from the German stock market
Authors: Grimberg Julia , Herberger Tim A.
Published: November 2020

While the occurrence of insider profits from directors’ dealings has been discovered for international stock markets, the industry effects of executives’ transactions have been scarcely part of previous research. Since on a firm-specific level, there are indications for a positive relation between companies’ investments in research and development (R&D investments) and abnormal returns, this paper examines whether these results also hold on an industry level. We elaborate and apply an event study for all companies listed in the HDAX at the German stock market between January 2013 and August 2018, firstly on an overall level and secondly on an industry level within the HDAX. Additionally, we analyze the switch in the regulatory framework from national to EU legislation (WpHG to MAR) in 2016 and the potential consequences for directors’ dealings and stock market reactions. Our analysis shows that insiders in general act as contrarian investors. However, our analysis of directors’ dealings related to potential industry effects does not lead to significant abnormal returns. The shift in insider trading regulation from German to European legislation in the middle of the sample period leads to a decreasing in abnormal returns over time. Our results are robust to different market models as well as size effects. We conclude that outside investors cannot profit from monitoring and analyzing directors’ dealings on an industry level and recommend a firm-specific level.
Synthesis and dyeing performance of some amphiphilic naphthalimide azo disperse dyes on polyester fabrics
Authors: Ameuru Umar , Yakubu Mohammed , Bello Kasali , Nkeonye Peter , Halimehjani Azim
Published: November 2020

A series of monoazo disperse dyes were synthesized by coupling diazotized
4-amino-N-dodecyl-1,8-naphthalimide with N,N-dialkyl anilines and naphthol
derivatives. The synthesized intermediates and the dyes were characterized
using FTIR, 1H-NMR, 13C-NMR, mass spectroscopy and elemental analysis (CHN).
Visible absorption spectra of the dyes were examined in solvents of
different polarities. The electronic absorption spectra cover a wavelength
(?max) range of 515-535 nm in DMF at uniformly absorption intensity between
1.59-3.00?104 L mol-1 cm-1. The dyes gave deep and bright intense hues of
light violet, maroon, pink and neon red on polyester fabrics. The dyes
generally showed good washing and perspiration rating but poor to moderate
light fastness properties on woven polyester fabric and could be recommended
for commercial outlets.
Differences in physiological responses to cardio-pulmonary exercise testing in adults with type 1 diabetes and controls without type 1 diabetes – a pooled analysis
Authors: Eckstein Max L. , Farinha Juliano Boufleur , McCarthy Olivia , West Daniel J. , Yardley Jane E. , Bally Lia , Zueger Thomas , Stettler Christoph , Boff Winston , Reischak-Oliveira Alvaro , Riddell Michael C. , Zaharieva Dessi P. , Pieber Thomas R. , Müller Alexander , Birnbaumer Philipp , Aziz Faisal , Brugnara Laura , Haahr Hanne , Zijlstra Eric , Heise Tim , Sourij Harald , Roden Michael , Hofmann Peter , Bracken Richard M. , Pesta Dominik , Moser Othmar
Published: November 2020

OBJECTIVE

To
investigate physiological responses to cardio-pulmonary exercise (CPX) testing
in adults with type 1 diabetes compared to age-, sex- and body mass index-
(BMI) matched controls without type 1 diabetes.

RESEARCH DESIGN AND METHODS

We
compared results from CPX tests on a cycle ergometer in individuals with type 1
diabetes and controls without type 1 diabetes. Parameters were peak and
threshold variables of oxygen uptake, heart rate and power output. Differences
between groups were investigated via restricted maximum likelihood modelling
and post-hoc tests. Differences between groups were explained by stepwise
linear regressions (p<0.05).

RESULTS

Among
303 individuals with type 1 diabetes (age 33 [22; 43] years, 93 females, BMI 23.6 [22; 26] kg/m2,
HbA1c 6.9 [6.2; 7.7]%; 52 [44; 61]
mmol/mol), peak oxygen uptake (32.55
[26.49; 38.72] vs. 42.67 ± 10.44) (mL/kg/min), peak heart rate (179 [170; 187] vs. 184 [175; 191]) (bpm) and peak power (216 [171; 253] vs. 245 [200; 300]) (Watt) were lower in comparison to 308 controls without type 1 diabetes (all
p<0.001). Individuals with type
1 diabetes displayed an impaired degree and direction of the heart rate to
performance curve compared against controls
without type 1 diabetes (0.07
[-0.75; 1.09] vs. 0.66 [-0.28; 1.45] (p<0.001)). None of the exercise physiological responses were
associated with HbA1c in individuals with type 1 diabetes.

CONCLUSIONS

Individuals
with type 1 diabetes show altered responses to CPX testing, which cannot be
explained by HbA1c. Intriguingly, the participants in our cohort
consisted of people with recent-onset type 1 diabetes, heart rate dynamics were
altered during CPX testing.
Island climate change adaptation and global public goods within the Belt and Road Initiative
Authors: Li Chunlin , Chen Jianqing , Grydehøj Adam
Published: November 2020

The Belt and Road Initiative (BRI), a project conceptualized and developed by the Chinese state, aims to enhance international cooperation, address issues of shared regional and global concern, and create opportunities for foreign direct investment in struggling economies. The BRI can be seen as a system for supplying global public goods, including sustainable development within which issues related to climate change sit. A great many small island states and territories are participating in the BRI, particularly in its constituent 21st-Century Maritime Silk Road. However, the BRI has not yet placed sufficient focus on climate change adaptation or issues specific to small islands. Furthermore, the BRI’s conceptual basis in rhetoric of mutual dependence and a community of common destiny have not always been evident in the individual activities that have been carried out within the BRI. If the BRI’s goals are to be taken seriously, it must do more to focus on the needs and perspectives of island communities, particularly with regard to climate change adaptation. This paper presents a framework for action to strengthen the BRI’s approach to islands and climate change adaptation in terms of information sharing, scientific and technological cooperation, financial support, and capacity building within a global governance framework.
PENERAPAN STRATEGI PRACTICE REHEARSAL PAIRS PADA MATA KULIAH SENI TARI DAN DRAMA DI UPGRIS
Authors: Arisyanto Prasena , Untari Mei Fita Asri , Sundari Riris Setyo
Published: November 2020

This study aims to measure student learning outcomes and analyze the character education process in dance and drama courses at UPGRIS PGSD Study Program through practice rehearsal pairs. The research method used is a quantitative-qualitative mixed method. The target of this research is focused on dance and drama lectures in the even semester 2017/2018. The research was conducted at the Elementary School Teacher Education Study Program, Faculty of Education, University of PGRI Semarang. There are 4 data collection techniques used in this study, namely observation, interview, questionnaire and document study. The data validity technique used is triangulation technique and source triangulation. Data analysis techniques use the Gain index formula for quantitative analysis, and analysis of learning concepts and character education for qualitative analysis.The results showed that the application of rehearsal pairs practice strategies can improve student learning outcomes in the appreciation of dance material by bringing Dolalak dance. Measurement of learning outcomes is done by Gain index and get the result of g = 1,02 or g bigger than 0,7 which is included in the high category. Increasing student learning outcomes are influenced by learning materials, learning methods, and student factors themselves. Students become more enthusiastic to practice outside of lecture hours because there are friends who become their study partners. The adoption of pairs of rehearsal practice strategies can also strengthen character education for students, including caring, cooperation, responsibility, and democratic character, which is strengthened through face-to-face lecture processes and independent training tasks.
PENGEMBANGAN MODEL PEMBELAJARAN GUIDED PROJECT BASED LEARNING UNTUK MAHASISWA SLOWLEARNER
Authors: Kurniawan Rahmat
Published: November 2020

This research and development aims to developing a learning model Guided Project Based Learning that can be implemented for slow learners or slow learners or normal students in one learning environment. This model was applied in Multimedia II course in STIKI Malang visual communication design study program for five meetings.The development method for developing this Guided Project Based Learning learning model uses the ADDIE model developed by Dick Carey. The steps of developing a learning model using the ADDIE development model consist of 5 steps, namely: 1) Analysis, 2) Design, 3) Development, 4) Implementation, 5) Evaluation. The sample in this study was the 5th semester visual communication design student where there were slowlearner students. Data was collected by mapping through the stages of psychological testing.The results of the mapping found 1 student with special needs slow learner type. Implementation of the GPBL model proves students can understand the material and follow systematically the design of simple games. In addition, the student is actively able to explain game design concepts.
ANALISIS PERMINTAAN DAN PENAWARAN LULUSAN SMK DALAM PEMENUHAN PASAR TENAGA KERJA
Authors: Perdana Novrian Satria
Published: November 2020

The objectives of this study are (1) to analyze DUDI demand on the competence ofvocational graduates in an effort to achieve a balance of the labor market, and (2) analyzethe supply of vocational graduates needed by DUDI in an effort to achieve a balance of thelabor market. In this study using qualitative approaches primary data analysis methods.This research was conducted in Central Java Province in 2018. The results of this studyare: (1) the qualifications of the workforce needed for DUDI in the middle to upper scaleare primarily having a certificate of competence, having IT and foreign language skills,and having experience working in the field the same for 1 year, and (2) the competencies ofvocational graduates produced have been sought to adjust DUDI's needs, but there arelimitations in the ability of vocational graduates because of the lack of facilities andinfrastructure in schools and the limited ability of educators.
UTILIZING WHATSAPP APPLICATION FOR TEACHING INTEGRATED ENGLISH (A CASE STUDY AT UNIVERSITY OF TECHNOLOGY YOGYAKARTA)
Authors: Dewi Septi Riana
Published: November 2020

This study aimed to illustrate some learning activities in Integrated English class byutilizing WhatsApp application and how the students respond to its implementation. The study was conducted in Accounting Department at University of Technology Yogyakarta. The subject of this study was 66 students in Accounting Class A of 2018/2019 Academic Year. The instruments to gather the data were observation, questionnaires and unstructrured interview. The result of this study showed that WhatsApp Application could be utilized as one of the beneficial devices to assist students in learning integrated English and there were positive responses from students during the implementation of WhatsApp in their learning process.
Early Repolarization, Fragmented QRS and Tpeak-Tend Interval as Electrocardiographic Markers in Patients with Idiopathic Ventricular Arrhythmias: a Brief Review
Authors: Vásquez Javier Pinos , Leiria Tiago Luiz Luz , Froemming Jr Clóvis , Finkler Bruno Schaaf , Zanotta Danilo Barros , Moreira Thiago Camargo , Kruse Marcelo Lapa , Pires Leonardo Martins , Lima Gustavo Glotz de
Published: November 2020

Introduction: Idiopathic ventricular tachycardia and ventricular fibrillation, as causes of sudden cardiac death, are entities with mechanisms poorly studied and understood to date. The electrocardiogram (ECG) is a simple tool, but with great diagnostic and prognostic value, which has allowed the identification of certain markers associated with increased risk of development of malignant ventricular arrhythmias and sudden cardiac death. Methods: To identify the electrocardiographic markers related to the risk of developing idiopathic malignant ventricular arrhythmias, a review of the literature was performed, looking for the most recent articles with the greatest scientific impact on the topic. Outcome: Although the number of studies published to date is scarce, the published evidence has shown three electrocardiographic risk markers that have emerged in recent years and which have been related to the development of idiopathic malignant ventricular arrhythmias: the early repolarization (ER) pattern, QRS fragmentation (QRSF) and the Tpeak-Tend (Tp-Te) interval. The ECG marker that has shown most evidence to date is the pattern of ER, as a cause of changes in both ventricular depolarization and repolarization. The QRSF and the Tp-Te interval have also been related to the development of idiopathic ventricular arrhythmias, although with less evidence in this regard. Conclusion: In the last years, three electrocardiographic markers have appeared as variables related to the development of malignant ventricular arrhythmias, as is the case of ER, QRSF and Tp-Te interval. However, evidence is scarce in this specific patient profile and further randomized clinical trials are necessary to demonstrate its true relationship and usefulness.
Tempo de travessia: narrativas da trajetória de uma professora alfabetizadora | Crossing time: Narratives of a literacy teacher’s trajectory
Authors: Costa Dania Monteiro Vieira , Monteiro Alzenira Barcelos
Published: November 2020

O artigo apresenta a história acadêmica e profissional de uma professora que trabalhou durante muitos anos em classes de alfabetização na rede pública municipal de ensino em Vila Velha (ES). Propõe, a partir de narrativas, desenvolver uma compreensão ativa e responsiva a respeito das transformações pelas quais passou a professora em relação às políticas, especialmente em relação aos programas de formação continuada de professores alfabetizadores, organizados no âmbito educacional, sob a justificativa de que minimizariam os problemas de aprendizagem das crianças que frequentavam/frequentam as salas de aula de alfabetização. Utiliza a abordagem qualitativa de pesquisa por meio da narrativa como fonte e método de investigação científica. Fundamenta-se na perspectiva bakhtiniana de linguagem, especificamente na noção de evento, que evidencia o ser no mundo a partir de uma consciência que se constitui na relação com o universo sociocultural. Conclui que o processo de compreensão ativa e responsiva por meio da escrita-evento, que se dá no ato de narrar sua história profissional em um processo de reflexão e diálogo, pode contribuir para a constituição do professor/sujeito de seu trabalho à medida em que desenvolve um posicionamento fundamentado em análises críticas sobre o fazer do processo ensinoaprendizagem com vistas à tomada de decisões, tendo como foco a criatividade e a inventividade que envolvem os atores do ato educativo.