bluuebunny/crossref_metadata_2025 huggingface dataset:
Part I: The Biological System of the Chemical Elements (BSCE) and the role of Lithium for mental health care
Authors: Markert Bernd , Wünschmann Simone , Rinklebe Jörg , Fränzle Stefan , Ammari Tarek
Published: May 2019

Background: In order to account for the physiological effects of chemical elements in living organisms using some Biological System of Elements (BSE) established by Markert in 1994 [1], the familiar Periodic Chemical System of Elements (PSE) according to Mendelejew and Meyer from 1869 was completed and modified using the Geochemical System of Elements (GSE) by Railsback [2-4, 5]. BSE goes beyond accumulating essentiality investigations, despite obvious technical and analytical limitations. In correlation among abundances of elements in different samples of biological origins, there are deep-rooted biochemical factors and relationships which these authors began studying and describing in more detail in the late 1990´s. Until the end of 2017, the BSCE was referred to as the Biological System of Elements (BSE).Lithium is not considered a vital or essential trace element. However, lithium is present in our body and has important functions, especially for the psyche. Specifically, lithium is important for mental health. The application of Li as pharmaceutical therapeutic equivalent for bipolar disorders (formerly called manic depressive disorders) is a well-known example of the use of a monovalent cation on neurological therapy. One of the main scientific objectives of this review and future research is the use of functional food in supporting and balancing the therapeutic dose of Li in the human body. In order to describe a possible application of a "functional food therapy by Li” and to meet its “scientific philosophy" a first look was given to Li-accumulating plants. We explain the use of plants containing high amounts of Li and described possible effects of increased Li concentrations in the human body.Finally, we should confirm if "natural food therapy” (for instance “green pills”) can positively support mental human health care benefits by fitting the ratio of Li / neurological diseases. For example, diseases like chronic bipolar disorders. Accordingly, the BSCE will continue to identify and investigate other chemical elements for using them in an effective Functional Food Therapy (FFT) of chronic neurological diseases and possibly other diseases. Keywords: Biological System of Chemical Elements (BSCE), Lithium (Li), Bipolar Disorders, Neurology, Functional Food Therapy (FFT), Chronic diseases
Functional foods, conventional treatment and bioactive compounds, assist in management of inflammatory bowel disease
Authors: Castaneda Lluvia , Singharaj Bryan , Martirosyan Danik
Published: May 2019

Background:Ulcerative colitis, ileal, and colonic Crohn’s disease are the most common inflammatory bowel diseases (IBS). The etiology of this group of diseases is complex and is still not entirely elucidated. Nonetheless, IBS is at least partially attributed to microbiota imbalance, which leads to an abnormal immune response. Due to the gravity of this condition, its impact of quality of life, and its increasing incidence, many investigations have been conducted with respect to conventional and alternative treatments. While conventional medicine is partially beneficial, it is unable to completely control the disease. Frequent relapses, symptomatology often persists. Specific diets, functional foods, and herbal medicine may offer a solution to restore intestinal microbiota and gut health and ameliorate some symptomatology. This review will focus on the diagnosis and management of IBD with respect to functional foods, bioactive compounds, and the potential of conventional treatment. Keywords: IBD, Crohn’s disease, ulcerative colitis, inflammation, treatment, microbiota, functional foods, bioactive compounds, bioactive ingredients, remission, effect.
Immunonutrition: Modulating the immune response in critically ill and surgical patients through nutrition
Authors: Louis-Jean Scarlet , Martirosyan Danik
Published: May 2019

Background: Immunonutrition is a term given to nutritional interventions that modulate the immune and inflammatory responses in critically-ill and surgical patients.  This is accomplished via the enteral or parenteral administration of formulas containing an array of immunonutrients in amounts greater than normally found in the diet. Some of the more commonly used immunonutrients include arginine, glutamine, branched-chain amino acids, omega-3 (n-3) fatty acids, trace metals (e.g. zinc, copper, iron), and nucleotides or antioxidants.
Effects of Namya Kanom Jeen powder extract on hypoglycemic and anti-oxidant properties in Alloxan-induced diabetic rats
Authors: Dat-arun Preeya , Leelawattana Rattana , Chinachoti Pavinee
Published: May 2019

Background: Diabetes mellitus (DM) is a major health care problem worldwide.  Major intervention control of DM is by using medical treatments and dietetic therapy.  Spices and herbs have been known to have anti-oxidant, anti-inflammation and anti-diabetic properties. Southern Thai foods known to contain phytochemicals in large amount, have been demonstrated to exhibit such properties and Namya Kanom Jeen (NKJ), a Southern Thai soup, shown to be most promising.  Here, we studied the effect of NKJ water extracts on hypoglycemic and anti-oxidant properties in Alloxan-induced diabetic rats.Methods: This study aimed to assess the effect of NKJ water extract on blood glucose, insulin, malondialdehyde (MDA), homeostatic model assessment of insulin resistance (HOMA-IR) and high sensitive C-reactive protein (hs-CRP) levels in Alloxan-induced diabetic (DM) rats for 3 weeks.Results: In Alloxan-induced diabetic rats, the NKJ water soluble extracts at 200, 1,000 and 2,000 mg/kg body weight doses (n=7) significantly lowered blood glucose, insulin, MDA, HOMA-IR levels compared to diabetic control (Metformin, p < 0.05). Conclusion: In summary, feeding of NKJ aqueous extract effectively lowered baseline blood glucose, insulin, MDA and HOMA-IR in diabetic rats.Keywords: Diabetes mellitus; Anti-oxidant; Glycemic; Insulin resistance; HOMA-IR, Namya Kanom Jeen powder
Hydroxypterocarpans with estrogenic activity in Aguaje, the fruit of Mauritia flexuosa (Peruvian moriche palm)
Authors: Shimoda Hiroshi , Takeda Shogo , Takarada Toru , Kato Yurina , Shimizu Norihito , Toda Kazuya , Nakamura Masafumi , Hanada Hiroshi , Nakamura Seikou , Matsuda Hisashi
Published: May 2019

Background: Phytoestrogens in edible plants, including soybean isoflavones and pomegranates, have been used for alleviation of premenopausal/postmenopausal syndromes and osteoporosis. Mauritia flexuosa (moriche palm) is grown in Peru and Brazil for its edible fruit that is said to contain phytoestrogens, but the relevant estrogenic compounds have not been identified. We investigated the constituents of moriche palm fruit extract and evaluated their estrogenic ability.Materials and methods: Ethyl acetate fraction of dried moriche palm was purified by column chromatography and HPLC chromatography. To evaluate estrogenic activity, we performed [1] simulation of binding to the human estrogen receptor (ER), [2] investigation of the proliferative effect on MCF-7 cells, and [3] the estrogen-chemically activated luciferase gene expression (E-CALUX) assay.Results: Two hydroxypterocarpans were isolated including lespeflorin G8 (LF) and 8-hydroxyhomopterocarpan (8-HHP).  The binding affinity of LF to ERa was higher than that of 8-HHP, with inhibition constants of 81.9 nM and 1.99 mM, respectively. However, LF and 8-HHP exhibited a similar proliferative effect on MCF-7 cells at 10 mM. The E-CALUX assay demonstrated that LF is a full ER agonist and 8-HHP is a partial agonist.Conclusion: LF was identified as a major estrogenic compound in the fruit of Mauritia flexuosa.Keywords: Mauritia flexuosa, moriche palm, lespeflorin G8, homopterocarpan, estrogenic activity, MCF-7, E-CALUX
Konsum als politische Praxis? Transformation des Alltags als Herausforderung und Chance
Authors: Witterhold Katharina
Published: May 2019

Ethische oder politische Anliegen nebenbei, beim täglichen Einkauf (mit-)zuverfolgen, gilt als niederschwellige Beteiligungsform. Doch ist der gelegentliche Kauf von Bio-Produkten mit anderen Formen politischer Beteiligung gleichzusetzen? Der ethnographische Blick auf den Alltag politischer Verbraucherinnen und Verbraucher zeigt, dass das Konzept eines nur marktvermittelten politischen Konsums zu kurz greift.
Erfolgsbedingungen für gesellschaftliche Veränderungsprozesse
Authors: Kristof Kora
Published: May 2019

Ressourcenleicht, immissionsneutral, gerecht ─ das sind die zentralen Ziele der anstehenden großen Veränderungen, wenn wir die Belastungsgrenzen des Systems Erde, das Wohlergehen aller Menschen und die Idee einer globalen, generationenübergreifenden Gerechtigkeit ernst nehmen. Dafür reicht es nicht, sich mit dem „Was soll sich ändern?“ zu beschäftigen. Zu fragen ist auch: „Was sind die zentralen Erfolgsfaktoren für gesellschaftliche Veränderungen?“
Marktwächter Digitale Welt: Schöne neue Shopping-Welt?
Authors: Dautzenberg Kirsti
Published: May 2019

Seit dem Jahr 2009 kann ein stetiger Anstieg des Gesamtumsatzes im deutschen Online-Handel beobachtet werden; nahezu drei Viertel aller Deutschen kaufen im Internet ein. Die Marktwächter beobachten und analysieren Verbraucherprobleme in der digitalen Welt. Anhand zweier vertiefender Untersuchungen werden exemplarisch Chancen und Risiken für Verbraucherinnen und Verbraucher im Online-Handel dargestellt und diskutiert.
Who cares? Sorgearbeit als individuelle Aufgabe und gesellschaftliche Herausforderung
Authors: Häußler Angela
Published: May 2019

Care-/Sorgearbeit im Haushalt wird überwiegend von Frauen übernommen, verbunden mit Einschränkungen für Lebensgestaltung und Einkommen. Aufgrund der ökonomischen und gesellschaftliche Ignoranz gegenüber unbezahlter, aber individuell und gesellschaftlich notwendiger Sorgearbeit entsteht eine strukturelle Rücksichtslosigkeit gegenüber Familien. In der Folge ist Care-Arbeit zu einer knappen Ressource geworden.
Active Involvement of People with Dementia: A Systematic Review of Studies Developing Supportive Technologies
Authors: Suijkerbuijk Sandra , Nap Henk Herman , Cornelisse Lotte , IJsselsteijn Wijnand A. , de Kort Yvonne A.W. , Minkman Mirella M.N.
Published: May 2019

Although there are promising benefits of supportive technology in dementia care, use of these technologies is still limited. It is challenging for researchers and developers in this field to actively involve people with dementia in development. This review updates and builds on existing knowledge by including a contemporary and relevant perspective. This perspective was gained by including search words and search databases from the field of Human Computer Interaction (HCI) and Design, as these fields were expected to supply novel insights in the complex task of actively involving people with dementia in developing supportive technologies. A total of 49 out of 3456 studies were included which describe the development of a great variety of technologies. Often people with dementia were involved in the generative or evaluative phase of the development. Interviews and observations were most commonly used methods. In seven articles the people with dementia were co-designers. This literature review reflects that people with dementia can influence the development of technology in regards to content, design, and even the initial idea, although the impact on how they experience their own involvement remains largely unknown. There is a lack of specific knowledge on appropriate methods and materials for active involvement of people with dementia in supportive technology development, even when including articles from the field of HCI and Design. Future research is needed to further appreciate and improve the desired role of people with dementia in meaningful technology development.
O-GlcNAcylation of Amyloid-β Protein Precursor by Insulin Signaling Reduces Amyloid-β Production
Authors: Kwon Oh Hoon , Cho Yoon Young , Kim Tae-Wan , Chung Sungkwon
Published: May 2019

Alzheimer’s disease (AD) is caused by the accumulation of neurotoxic amyloid-β (Aβ) peptides. Aβ is derived from amyloid-β protein precursor (AβPP). In the non-amyloidogenic pathway, AβPP is cleaved by α-secretase and γ-secretase at the plasma membrane, excluding Aβ production. Alternatively, AβPP in the plasma membrane is internalized via endocytosis, and delivered to early endosomes and lysosomes, where it is cleaved by β-secretase and γ-secretase. Recent studies have shown that insulin in the periphery crosses the blood-brain barrier, and plays important roles in the brain. Furthermore, impaired insulin signaling has been linked to the progression of AD, and intranasal insulin administration improves memory impairments and cognition. However, the underlying molecular mechanisms of insulin treatment remain largely unknown. To investigate the effects of insulin on AβPP processing, we tested the effects of insulin on neuroblastoma SH-SY5Y cells overexpressing AβPP, and cultured rat cortical neurons. We found that insulin increased the level of cell surface AβPP, decreasing the endocytosis rate of AβPP. Insulin reduced Aβ generation through upregulation of AβPP O-GlcNAcylation via Akt insulin signaling. Our present data suggest that insulin affects Aβ production by regulating AβPP processing through AβPP O-GlcNAcylation. These results provide mechanistic insight into the beneficial effects of insulin, and a possible link between insulin deficient diabetes and cerebral amyloidosis in the pathogenesis of AD.
A Pilot Study of Changes in Medial Temporal Lobe Fractional Amplitude of Low Frequency Fluctuations after Sildenafil Administration in Patients with Alzheimer’s Disease
Authors: Samudra Niyatee , Motes Michael , Lu Hanzhang , Sheng Min , Diaz-Arrastia Ramon , Devous Michael , Hart John , Womack Kyle B.
Published: May 2019

Alzheimer’s disease (AD) is the most common cause of neurodegenerative cognitive impairment, defined by abnormal accumulations of amyloid-β and tau. Approaches directly targeting these proteins have not resulted in a disease modifying therapy. Neurovascular unit dysfunction is a feature of AD offering an alternative target for intervention. Sildenafil, a phosphodiesterase 5 (PDE5) inhibitor, improves cognitive functioning in mouse models of AD. Recent work in AD patients has demonstrated increased cerebral blood flow, as well as brain oxygen utilization after a single dose of sildenafil. Its effect on nitric oxide-cGMP signaling may have downstream effects on neuroplasticity, amyloid-β processing, and improved neurovascular unit function. Fractional amplitude of low frequency fluctuations (fALFF) assesses spontaneous neural activity via resting state fMRI BOLD signal (0.01–0.08 or 0.10 Hz). In AD, other assessments have revealed increased fALFF in hippocampi and parahippocampal gyri. Here, we examined the effects of a single dose of sildenafil on fALFF in a cohort of 10 AD patients. We found a decrease ( p < 0.03, α= 0.05) in fALFF an hour after sildenafil administration in the right hippocampus. Additionally, cerebral vascular reactivity in response to carbon dioxide inhalation, a measure of neural vascular reserve previously collected on most of these participants, was not significantly correlated with this decrease, implying that change in fALFF may not have been solely due to altered vascular reactivity to CO2. We demonstrate that in patients with AD, hippocampal fALFF decreases in response to sildenafil, suggesting a normalization. These findings support further investigation into the effects of sildenafil in AD.
Challenges to and Facilitators of Recruitment to an Alzheimer’s Disease Clinical Trial: A Qualitative Interview Study
Authors: Clement Clare , Selman Lucy E. , Kehoe Patrick G. , Howden Beth , Lane J. Athene , Horwood Jeremy
Published: May 2019

Background:

Low participation in clinical trials is a major challenge to advancing clinical Alzheimer’s disease (AD) research and care. Factors influencing recruitment to AD trials are not fully understood.

Objective:

To identify barriers to, and facilitators of, recruitment in a UK multi-center, secondary care AD trial (Reducing pathology in Alzheimer’s Disease through Angiotensin TaRgeting (RADAR) trial) and implications for improving recruitment to AD trials.

Methods:

Semi-structured qualitative telephone interviews with a purposive sample of 17 trial site staff explored the RADAR trial recruitment pathway and views and experiences of recruitment. Interviews were analyzed thematically.

Results:

Diagnostic and care pathways hindered identifying patients with mild-moderate AD, with a lack of up-to-date patient records and data access problems affecting screening. Research is not routinely embedded in AD care but facilitated recruitment when it was. Clinicians’ and patients’ favorable view of the trial purpose facilitated recruitment, although the complexity of participant information sheets and requirement for study companion created challenges.

Conclusion:

These findings have important implications for the design of future AD trials and for planning how to best interface with clinical commitments to ensure sufficient and timely recruitment. Challenges to AD trial recruitment can occur at care pathway, clinician, and patient and companion levels. Recruitment can be facilitated by: improving diagnostic processes and systems for recording and sharing patient information, embedding research into routine patient care, collaborating with a range of services to identify and approach eligible patients, training and engaging trial staff, and providing patients with clear and concise study information.
Serum Insulin-Like Growth Factor I Deficiency Associates to Alzheimer’s Disease Co-Morbidities
Authors: Zegarra-Valdivia Jonathan A. , Santi Andrea , Fernández de Sevilla Maria Estrella , Nuñez Angel , Torres Aleman Ignacio
Published: May 2019

Increasing evidence supports the notion that Alzheimer’s disease (AD), a condition that presents heterogeneous pathological disturbances, is also associated to perturbed metabolic function affecting insulin and insulin-like growth factor I (IGF-I). While impaired insulin activity leading to insulin resistance has been associated to AD, whether altered IGF-I function affects the disease is not entirely clear. Despite the limitations of mouse models to mimic AD pathology, we took advantage that serum IGF-I deficient mice (LID mice) present many functional perturbations present in AD, most prominently cognitive loss, which is reversed by treatment with systemic IGF-I. We analyzed whether these mice display other pathological traits that are usual co-morbidities of AD. We found that LID mice not only display cognitive disturbances, but also show altered mood and sociability, increased susceptibility to epileptiform activity, and a disturbed sleep/wake cycle. Collectively, these data suggest that reduced IGF-I activity contributes to heterogeneous deficits commonly associated to AD. We suggest that impaired IGF-I activity needs to be taken into consideration when modeling this condition.
Vibrating Tail, Digging, Body/Face Interaction, and Lack of Barbering: Sex-Dependent Behavioral Signatures of Social Dysfunction in 3xTg-AD Mice as Compared to Mice with Normal Aging
Authors: Torres-Lista Virginia , Giménez-Llort Lydia
Published: May 2019

Modeling of Alzheimer’s disease (AD), classically focused on the subject-environment interaction, foresees current social neuroscience efforts as improving the predictive validity of new strategies. Here we studied social functioning among congeners in 13–14-month-old mice with normal aging in naturalistic and experimental conditions and depicted behavioral signatures of dysfunction in age-matched 3xTg-AD mice. The most sensitive variables were vibrating tail, digging, body/face and self-grooming, that can be easily used in housing routines and the assessment of strategies. Sex-specific signatures (vibrating tail, digging, and grooming) defined female 3xTg-AD mice ethogram. All animals sleep huddled while barbering was only found in females with normal aging.
PREVENTIVE REGULATIONS TO REMOVE ENVIRONMENTAL DAMAGE TO MANGROVE ECOSYSTEM AT EAST KALIMANTAN, INDONESIA
Authors: Kotijah Siti , Ventyrina Ine
Published: May 2019

Indonesia is an archipelago state composed with thousands of large and small islands. Mangrove restoration got widespread attention given the high economic and social value of ecosystem ecology. Restoration may raise the value of mangrove biodiversity resources, give the livelihoods of the population, prevent damage to the beach, keepbiodiversity, fisheries, and others. This paper proposes legal frameworks to support to counteract damage to mangrove ecosystem at East Kalimantan based on Indonesian regulations.
ANALISIS PRIORITAS PEMBANGUNAN DAERAH BERDASARKAN PENGARUH REGIONAL, SPESIALISASI DAERAH, DAN KEUNGGULAN KOMPETITIF EKONOMI SEKTORAL DI KABUPATEN ACEH JAYA
Authors: Pradana Reza Septian
Published: May 2019

Penelitian ini bertujuan untuk mengidentifikasi sektor-sektor ekonomi yang akan dijadikan prioritas pembangunan daerah berdasarkan pengaruh regional, spesialiasi daerah, dan keunggulan kompetitif ekonomi sektoral di Kabupaten Aceh Jaya. Penelitian ini menggunakan analisis model shift share dan analisis inferensia dengan metode regresi linear berganda. Hasil estimasi dengan analisis linier berganda menunjukkan bahwa variabel spesialisasi daerah yang diukur dengan nilai Proportionality Shift (PS) dan keunggulan kompetitif yang diukur dengan nilai Differential Shift (DS) secara signifikan berpengaruh postif terhadap Pertumbuhan Ekonomi sedangkan variabel pengaruh daerah yang diukur dengan nilai Regional Share (RS) tidak berpengaruh secara signifikan terhadap Pertumbuhan Ekonomi. Prioritas Pembangunan Daerah dapat diarahkan pada pembangunan sektor-sektor ekonomi yang memiliki tingkat spesialisasi daerah dan keunggulan kompetitif yang tinggi. Berdasarkan hasil analisis Model Shift Share, dua sektor yang memiliki tingkat spesialisasi daerah tertinggi yaitu Sektor Pertanian, Kehutanan, dan Perikanan dan Sektor Konstruksi. Kemudian, dua sektor yang memiliki tingkat keunggulan kompetitif tertinggi yaitu Sektor Pertambangan dan Penggalian dan Sektor Industri Pengolahan.
TEKNIK PENANAMAN JAJAR LEGOWO UNTUK PENINGKATAN PRODUKTIVITAS PADI SAWAH DI JAWA TENGAH
Authors: Prasetyo Octavia Rizky , Kadir Kadir
Published: May 2019

Penelitian ini bertujuan menganalisis sebaran implementasi sistem tanam jajar logowo dalam budidaya tanaman padi sawah di Provinsi Jawa Tengah serta dampaknya terhadap peningkatan produktivitas tanaman padi. Data yang digunakan adalah hasil Survei Struktur Ongkos Usaha Tanaman Pangan 2017 yang dilaksanakan oleh BPS. Analisis spasial dan estimasi model regresi OLS digunakan untuk mencapai tujuan. Hasil penelitian menunjukkan meski sistem tanam jajar legowo menjanjikan produktivitas yang lebih tinggi, proporsi rumah tangga padi sawah yang menerapkan teknik ini masih relatif kecil, yakni hanya sebesar 32,05 persen dari total rumah tangga usaha tanaman padi sawah. Kabupaten/kota dengan tingkat implementasi sistem tanam Jajar Legowo relatif tinggi terkonsentrasi di Kabupaten Prubalingga, Banjarnegara, Grobogan, Kudus, Demak, Temanggung, dan Kendal. Sementara itu, hasil estimasi regresi OLS mengkonfirmasi bahwa sistem tanam jajar legowo berdampak signifikan terhadap peningkatan produktivitas sampai dengan 16 persen dibandingkan dengan teknik penanaman lainnya. Karena itu, meningkatkan partisipasi petani dalam implementasi sistem tanam ini dapat menjadi salah satu upaya yang dapat ditempuh untuk meningkatkan produksi padi secara signfikan di Provinsi Jawa Tengah. Selain itu, meningkatkan kapasitas petani, penggunaan benih unggul dan alsintan, dan meningkatkan akses petani untuk mendapatkan pinjaman modal dari bank juga berdampak signifikan dalam meningkatkan produktivitas tanaman padi sawah yang dibudidayakan oleh petani.
ALIHFUNGSI LAHAN MENGUBAH WAJAH DESA
Authors: Leonis Gerald Noveriano
Published: May 2019

Desa merupakan suatu unit sosial penting dalam ruang hidup yang juga mengalami dinamikanya. Berbeda dengan kota, desa memberikan kita perpsektif tentang konstruksi nilai dan historis. Dengan perkembangan serta ledakan penduduk yang tidak terkontrol berdampak pula pada perubahan wajah desa. Kota yang padat memaksa penduduknya bermigrasi mencari lahan di desa. Penelitian ini bertujuan untuk memaknai perubahan wajah desa akibat dari migrasi penduduk kota. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus. Pengumpulan data dilakukan dengan wawancara, observasi dan studi dokumen. Penelitian ini mengambil responden dari masyarakat awal, pendatang (penduduk kota) yang membangun hunian di desa, serta aparatur desa. Berdasarkan hasil penelitian, ada beragam dampak yang terjadi akibat dari migrasi penduduk kota ke desa. Bangunan hunian yang berbeda, kemapanan ekonomi yang lebih baik memberikan signal akan terjadi kesenjangan sosial di desa, dan hal ini memberikan impuls terjadinya dekohesivitas sosial.
Celebrity Endorsement’s Effects on Youths’ Cosmetic Buying Behavior: A Study in a Malaysian University
Authors: Lai Meng Lee , Hui Meian Kok
Published: May 2019

The Malaysian cosmetic industry is currently operating in a competitive market. For brands to stand out and gain a competitive advantage over others, marketers are turning towards the use of celebrity endorsement in advertisements. Therefore, it is important for advertisers of cosmetic brands to be aware of the properties in celebrity endorsement that can influence their customer’s buying behavior. The objective of this study is to investigate the significant effects of celebrity credibility, attractiveness and popularity on female youth’s cosmetic buying behavior. This quantitative cross sectional study utilizes data obtained from a personally administered questionnaire. A sample of 253 female youths from a university was chosen using the convenience sampling method. Various statistical analyses were conducted via the SPSS statistical package. The findings indicate that the properties of celebrity attractiveness and popularity had positive and significant effects on consumer buying behavior, however, celebrity credibility did not. This suggests that female youths are more concerned about the physical attractiveness and likeability of the endorsers when making decisions, whilst not concerned about the credibility of the endorser such as expertise and trustworthiness. The study concludes with the discussion and implications as well as limitations and suggestions for future re-search.
Enfrentamento, Dificuldades e Práticas de Autocuidado de Pacientes com Doença Renal Crônica Submetidos à Diálise Peritoneal
Authors: Gomes Hanna Lorena Moraes , Monteiro Iago Orleans Pinheiro , Pina Rizioléia Marina Pinheiro , Toledo Noeli das Neves , Almeida Gilsirene Scantelbury de
Published: May 2019

Objetivos: Compreender o enfrentamento, as dificuldades e as práticas de autocuidado utilizadas por pessoas com doença renal crônica, submetidas ao tratamento por diálise peritoneal, por meio de uma síntese de estudos, primários e elegíveis, encontrados na literatura. Resultados: Foram selecionados 09 artigos provenientes das bases de dados LILACS, IBECS e BDENF, com base nos critérios de inclusão e exclusão. Sendo, quatro na língua portuguesa, dois na língua inglesa e três na língua espanhola. Os resultados foram discutidos em categorias específicas. Conclusão: A experimentação de um novo momento da vida do individuo acometido por Doença Renal Crônica que consequentemente, o leva ao tratamento por Diálise Peritoneal. Essa doença traz grandes mudanças no estilo de vida do acometido. Toda essa situação deve ser muito bem considerada pelo profissional de enfermagem que será o principal intermediador para o êxito nesse processo de tratamento. É esse profissional de saúde que deverá dá suporte para a família do enfermo e conduzir o paciente a receber um tratamento com todos os cuidados necessários para obter um bem-estar físico e emocional em sua nova etapa de vida.
Disiplin Soruşturmalarında Hukuka Aykırı Deliller
Authors: Fiş Üstün Gül
Published: May 2019

Kamu görevlilerinin çalıştıkları kurumun düzenini bozan veya kurumun sunduğu hizmetin düzgün

yürütülmesini engelleyen faaliyetleri disiplin hukukunun konusunu oluşturmaktadır. Disiplin hukuku

söz konusu ihlalleri gerçekleştiren kamu görevlisinin daha dikkatli ve özenli davranmasını sağlayacak,

mali haklarına ve mesleki statüsüne etki yapmaya yönelik disiplin cezalarını ve bu cezalara ilişkin

başvurulabilecek yolları ve disiplin cezasının tesisi için gereken disiplin soruşturma sürecini konu

almaktadır.

Disiplin soruşturmasını yürüten soruşturmacı; soruşturma konusuyla sınırlı olmak üzere her nevi

evrakı incelemeye, ilgili kurumlardan ve kişilerden bilgi ve belge almaya, tanık dinlemeye, mahallinde

keşif yapmaya, hakkında soruşturma yapılan memurun savunmasını almaya, soruşturma raporu

düzenlemeye yetkilidir. Ancak, soruşturmacıya tanınan bu yetkilerin kullanımı sırasında veya

soruşturma raporunun tesisi sırasında yapılan değerlendirmelerde bazı hatalar, hukuka aykırılıklar

meydana geldiği de görülmektedir.

Danıştay’ ın bir kısım kararlarında, disiplin hukukunun bağımsız olduğu, ceza soruşturmalarından

disiplin soruşturmalarını bağlamadığı ilkeleri zikredilerek, hukuka aykırı delillerin disiplin

soruşturmalarında kullanılmasına engel olmadığı yönünde hükümler tesis edilmiştir. Ancak, Danıştay

yakın dönemlerde kararlarını değiştirmiş, Anayasamızın 38. maddesinde öngörülen hukuka aykırı

elde edilen bulguların delil olarak kullanılmamasını yönündeki ilkenin disiplin soruşturmalarında

uygulanması mümkün hale gelmiştir.
Anayasacılığın Uluslararası Hukuk Bakımından Uygulanabilirliğinde Dikkate Alınması Gereken Bazı Temel Hususlar
Authors: Akkutay Ali İbrahim
Published: May 2019

Anayasacılık, uluslararası hukukun tartışma konusu olan en güncel konularından birisidir. Uluslararası hukukta meşruiyet başta olmak üzere pek çok sorunun ancak anayasacılık yoluyla çözülebileceğini savunan çok sayıda yazar bulunmaktadır. Bununla birlikte anayasacılığın uygulanmasına yönelik savunulan fikirlerin ve üzerinde durulan hususların kapsamı yazarların konuya yaklaşımına göre farklılık gösterebilmektedir. Çalışmada anayasacılığın, uluslararası hukukun güncel haliyle uygulanmasının ilişkili olduğu bazı temel hususlara dair değerlendirmelerde bulunulmaktadır.
Türk Hukukunda Kültür Varlıklarının Mülkiyeti
Authors: Özel Sibel
Published: May 2019

Kültür varlıklarının korunması meselesi kültür varlıkları üzerindeki mülkiyet hakkıyla yakından bağlantılıdır. Bu nedenle kültür varlığı açısından zengin kaynak ülkeler bir kanun hükmüyle kendi topraklarında bulunan bütün objeler üzerinde devlet mülkiyeti tesis etmeyi tercih etmektedir. Böylelikle menşe ülke ipso iure bulunan objelerin maliki olmaktadır. Türkiye de bir kaynak ülke olarak 1884’den beri bulunan bütün arkeolojik objelerin kanun gereği devlet mülkiyetine tâbi olduğu prensibini kabul etmiştir.Bununla birlikte özel mülkiyete tâbi diğer çeşit kültür varlıkları da bulunmaktadır. Kanun kapsamında kültür varlığı tanımı ile kültür varlığı üzerinde devlet mülkiyeti kavramı birbirinden farklıdır. Bu makalede kamu mülkiyeti tanımı ile kültür varlığı tanımı arasındaki farklar irdelenmektedir.
Die Prüfung der Sachentscheidungsvoraussetzungen in der Neuen Türkischen Zivilprozessordnung
Authors: Özkaya Ferendeci Özden
Published: May 2019

In der vorliegenden Arbeit wir die bis dato strittige Prüfungsreihenfolge der Sachentscheidungsvoraussetzungen, die in der neuen türkischen Zivilprozessordnung mit der Gesetzesnummer 6100 in § 114 das erste mal eine normative Grundlage bekommen haben, untersucht. Die rechtliche Natur der Sachentscheidungsvoraussetzungen sind, dass sie der ordre public angehören und somit wie wichtige Voraussetzung für den Prozess darstellen. Das Gericht muss das Vorliegen der Sachentscheidungsvoraussetzungen von Amts wegen in jedem Verfahrensabschnitt beachten und auch die Parteien können in jedem Verfahrensabschnitt das Fehlen der Sachentscheidungsvoraussetzungen geltend machen. Es wird der Frage nachgegangen, ob beim Fehlen einer Sachentscheidungsvoraussetzung die Klage sofort als unzulässig abzuweisen ist, oder ob trotzdem noch die folgenden Sachentscheidungsvoraussetzungen zu überprüfen sind. Hierbei wird auch auf die Prozessökonomie verwiesen und der Unterschied einer Klageabweisung wegen Unzulässigkeit und Begründetheit herausgearbeitet. Insofern wird auch darauf hingewiesen, dass eine Klage nur auf ihre Begründetheit hin überprüft werden kann, wenn alle Sachentscheidungsvoraussetzungen vorliegen und auch während des ganzen Prozesses bestehen bleiben. In diesem Zusammenhang wird auch untersucht, wie das Gericht handeln muss, wenn die bei Prozessbeginn fehlende Sachentscheidungsvoraussetzung nicht bemerkt wurde und wenn das Fehlen im Laufe des Prozesses geheilt wird.
Anayasa Mahkemesi’nin 2014/12321 Başvuru Numaralı ve 20.07.2017 Tarihli Tari Kararı’nın Değerlendirilmesi
Authors: Çavdar Pelin
Published: May 2019

Arsa payı karşılığı inşaat sözleşmesinde yüklenici, finansal veya ticari sebeplerle, arsa sahibi ile yapmış olduğu arsa payı karşılığı inşaat sözleşmesinden doğan alacağını üçüncü kişiye devredebilir. Karara konu uyuşmazlıkta da, yüklenicinin bağımsız bölüm ve arsa paylarının devrinin talebine ilişkin alacak hakkını alacağın devri yoluyla üçüncü kişiye devrettiği anlaşılmaktadır. Yüklenici ise sözleşmede kararlaştırılan şekilde inşaatı tamamlamadığı için, arsa sahibinin yüklenici ve üçüncü kişi adına tescil edilmiş olan tapu kayıtlarının iptali ve kendi adına tescili istemi ilk derece mahkemesi, Yargıtay ve Anayasa Mahkemesi tarafından kabul edilmiştir. Kanaatimizce, verilen karar sözleşmeden dönme teorileri, tapu siciline egemen olan ilkeler ve TMK md.2 bağlamında uyandırılan güvene aykırı davranış (çelişkili davranış yasağı) oluşturması ve hukuki güvenlik ilkesini de göz ardı etmesi gerekçeleriyle yerinde değildir.
Uzlaştırmanın Kapsamı ve Şartları
Authors: Çakır Kerim
Published: May 2019

   
Tanzimat Sonrası Vergi Reformlarının Anayasal Vergilendirme İlkeleri Çerçevesinde Değerlendirilmesi
Authors: GÜNAY Berrin , TEKİR Asım Furkan
Published: May 2019

Günümüz vergi hukukunun köklerini ve ruhunu özellikle Tanzimat sonrası olmak üzere geç dönemOsmanlı vergi reformlarında bulmak mümkündür. Bu tarihî devir, anayasal vergilendirme ilkelerininnasıl bir değişim yarattığının aşama aşama gözlenebildiği bir gözlem alanı olarak esaslı bir önem veelverişlilik arz etmektedir. Bu çalışma, işbu döneme günümüzde ayrıntılı bir şekilde tanımlanmış olananayasal vergilendirme ilkeleri ışığında bakmayı amaçlamıştır. Bu çerçevede, öncelikle vergilendirmeilkelerinin neler olduğu ortaya konulmaya çalışılmış, daha sonra klasik Osmanlı vergi sisteminin builkeler bakımından ne durumda olduğu kısaca değerlendirilmiş, ardından vergi konusundaki Tanzimatdöneminden Meşrutiyet dönemini de kapsayacak biçimde Cumhuriyete kadarki anayasal ve diğerhukukî düzenlemeler ve somut tarihî vakıalar ve gelişmeler yorumlanarak nihayetinde ilkelere neölçüde riayet edildiği hakkında bir sonuca varılmaya çalışılmıştır.
Tüketici Hukukunda İş Görme (Hizmet) Sözleşmelerinde Ayıplı İfa
Authors: BAŞ SÜZEL Ece
Published: May 2019

6502 sayılı Tüketicinin Korunması Hakkında Kanun’un kapsamı, eski Kanun’a kıyasla genişletilmiş ve hizmet sözleşmeleri adı altında, bir işin görülmesine yönelik sözleşmelerin de kapsama dahil olduğu kabul edilmiştir. Buna örnek olarak, vekâlet sözleşmesi, sigorta sözleşmesi, taşıma sözleşmesi, kira sözleşmesi ve eser sözleşmesi gösterilebilir. Bu sözleşmelerin bazılarında ayıplı ifa söz konusu olabilecektir. Ancak bazılarında ise, bir sonuç taahhüdü bulunmadığından, ayıplı ifadan söz edilemez. TKHK m. 15, ayıplı ifa halinde tüketicinin sahip olduğu hakları düzenlemektedir. Ancak bunların işin niteliğine ne kadar uygun olduğu tartışılmalıdır.
Ceza Koşulunun Borçlunun Borca Aykırı Davranıştaki Kusuru İle İlişkisi Nedir?
Authors: AKSOY Hüseyin Can
Published: May 2019

İsviçre hukukunda ceza koşulunun borçlunun kusuruna bağlı olduğu konusunda neredeyse görüş birliği bulunmaktadır. Türk hukukunda ise ceza koşulu ve kusur arasındaki ilişki tartışmalıdır. Zira kimi yazarlar, cezanın yalnızca borçlunun kusuruyla borca aykırı davrandığı hallerde istenebileceğini kabul ederken, diğer bir görüşe göre cezanın istenebilmesi borçlunun kusuruna bağlı değildir. Bu görüşlerden hangisinin kabul edilmesi gerektiğinin tespiti, Türk Borçlar Kanunu’nun 180/2 ve 182/2 maddelerinin, hazırlık çalışmalarını da dikkate alarak, sözüyle ve özüyle yorumlanmasını gerektirir. Kanımızca, bu yorum neticesinde varılacak sonuç, taraflarca aksine anlaşma yapılmadıkça, borçlunun sözleşmeyle belirlenen cezayı ödeme borcunun kusurundan bağımsız olduğudur.
Uluslararası Ticaret ve Yatırım Hukuku Bakımından Tütün Ürünlerinin Düz Paketlenmesi Meselesi
Authors: KAYA Talat
Published: May 2019

Dünya Sağlık Örgütü bünyesinde kabul edilen Tütün Kontrolü Çerçeve Sözleşmesi sonrasında başta Avustralya olmak üzere, birçok ülke tarafından tütün ürünlerinin düz paketlenmesine yönelik düzenlemeler kabul edilmiştir. Düz paket düzenlemeleri ile tüm tütün mamullerinin ilgili otorite tarafından belirlenecek standart bir renkte paketlenmesi zorunlu kılınmaktadır. Ayrıca, paket üzerinde marka ve ürün adının ilgili otorite tarafından belirlenecek belli bir yazı tipi stili ve boyutunda yer alması dışında logolarının, marka tasvirlerinin, renklerin ve tanıtım metinlerinin tütün ürünleri ve perakende paketleri üzerine konulması yasaklanmaktadır. Tütün firmalarınca uygulamanın başta fikri mülkiyet hakları olmak üzere ulusal ve uluslararası düzeyde ticaret ve yatırım kurallarını ihlal ettiği ileri sürülmüş ve düz paket uygulamasına geçen ülkelere karşı dava süreçleri başlatılmıştır. Söz konusu davaların önemli bir kısmı tamamlanmış olmakla birlikte, halen süren davalar da bulunmaktadır. Bu davalar ile ileride açılması muhtemel davaların sonuçları, düz paket uygulamasının dünya çapında geleceğini belirleyecektir.
First record of the fireworm Hermodice carunculata preying on colonies of the threatened staghorn coral Acropora Cervicornis in the southeastern outplanting sites of the Dominican Republic
Authors: Calle-Triviño Johanna , Cortés-Useche Camilo , Sellares Rita , Arias González Jesús Ernesto
Published: May 2019

Several fireworms Hermodice carunculata (Pallas, 1766) were observed feeding on coral colonies or transplanted fragments of the threatened staghorn coral Acropora cervicornis (Lamarck, 1816), in outplanting sites at Bayahibe, Dominican Republic. The fireworm H. carunculata has a highly negative impact on A. cervicornis populations, causing several lesions on the living tissue of branches and partial or complete mortality at the outplanting sites. This is the first report of predation on transplanted colonies in a coral restoration program in the Dominican Republic.
Nuevos registros fósiles de vertebrados terrestres para Las Llanadas, Sancti Spíritus, Cuba
Authors: Aranda Ernesto , Martínez López Joao G. , Jiménez Osvaldo , Alemán Luna Carlos , Viñola López Lázaro William
Published: May 2019

El depósito paleontológico Las Llanadas es un manantial con sedimento rico en materia orgánica. Estudios del sitio a principios del siglo XX, dieron a conocer materiales fósiles de perezosos, cocodrilos, tortugas terrestres, y jutías. Dos especies de perezosos, Acratocnus antillensis y Neocnus gliriformis, fueron nuevas para la ciencia. En el presente trabajo se dan a conocer nuevos registros fósiles de anuros, un reptil y aves para el depósito: Peltophryne empusus, Osteopilus septentrionalis, Cyclura nubila, Tyto alba, Buteogallus borrasi y Boromys ofella. Huesos recientes de Lithobates catesbeianus y Capromys pilorides se encontraron entre los materiales, lo que indica que el depósito se mantiene activo en la recepción de especímenes. De un total de 2030 piezas solo 3% pudo ser identificado taxonómicamente, debido al alto nivel de fragmentación.
Primer hallazgo de la familia Trischizostomatidae Lilleborg, 1865 (Amphipoda: Gammaridea: Lysianassoidea) en el Mar Caribe
Authors: Varela Carlos , Bracken-Grissom Heather D.
Published: May 2019

Se presenta el primer registro para el Mar Caribe de una especie de la familia Trischizostomatidae.
On the relationship among birds and Trema micrantha in montane forests of Hispaniola
Authors: Latta Steven C.
Published: May 2019

Avian frugivores are of great interest to ecologists because they play an important role in ecosystem functioning, and can serve as important components in habitat restoration. In the Neotropics, observational studies have demonstrated the importance of a variety of fruit trees to numerous bird species, but undoubtedly other tree species exist that are a key resource for birds. I explored the relationship between Trema micrantha (L.) Blume, which produces superabundant fruit nearly continuously, and its disperser assemblage in Hispaniolan pine forest and montane broadleaf forest in the Sierra de Bahoruco, Dominican Republic. In 174 hours of observation at sixteen trees I recorded 513 visits by nineteen species of birds. Birds did not visit Trema in numbers reflecting their relative abundance in each habitat. The most frequent consumer of Trema fruit was the migratory Cape May Warbler, Setophaga tigrina (Gmelin, 1789), but other frequent visitors included the Black-throated Blue Warbler, S. caerulescens (Gmelin, 1789), and the endemic Palmchat, Dulus dominicus (Linnaeus, 1766), and Hispaniolan Highland-Tanager, Xenoligea montana (Chapman, 1917). I recorded 85 aggressive interactions among nine species of birds in Trema trees, with female Cape May Warblers involved in most of these. There was no evidence that Trema was dependent on any one species of bird for dispersal of its seeds, and despite the large proportion of visits by the Cape May Warbler, I found no evidence that any species of bird was dependent upon fruit from Trema. Rather, because male Cape May Warblers dominate females and defend nectar sources in these habitats, I suggest that for female  Cape May Warblers, these scattered Trema trees represent a known, reliable, and accessible source of food which they can defend. Trema trees will benefit these bird species as a food resource, but may also function as a target for many other birds moving across the landscape, thereby facilitating the dispersal of a wider variety of seeds and the restoration of deforested sites.
Distribución y abundancia del pez león Pterois volitans en la zona costera de uso turístico de Holguín, Cuba
Authors: Reynaldo Enrique , Vega Antonio , Fernández Alejandro , Cruz José , Córdova Elier , Cruz Pedro
Published: May 2019

En Cuba, a partir del 2007, se detectó la presencia de Pterois volitans, comúnmente llamado Pez León, especie invasora causante de grandes daños a comunidades ictiológicas autóctonas en diferentes regiones del mundo. Este trabajo se propuso determinar la distribución y abundancia del Pez León en diferentes sitios de muestreo en la zona costera de uso turístico de Holguín. El estudio se realizó en ocho campañas de muestreo durante el período abril-noviembre de 2016. Se seleccionó un total de siete sitios de monitoreo distribuidos en dos municipios de la provincia Holguín (Rafael Freyre y Banes). Se determinó la abundancia promediando los valores de cada recorrido lineal (individuo por cada 100 m2). Se determinó la talla y el peso por estación de muestreo con una cinta métrica y una balanza digital. La comparación múltiple de medias se realizó por PERMANOVA con 10 000 permutaciones empleando la distancia euclidiana. Se registró un total de 365 individuos. El sitio con mayor densidad fue Playa Blanca,  con 12.42 ind/100 m2 y el de menor abundancia playa Don Lino, con 3.66 ind/100 m2, detectando solamente diferencia estadística entre este sitio con el resto de los sitios monitoreados.  El mes con mayor densidad en el año de estudio fue abril, con 13.14 ind/100 m2, registrándose diferencias estadísticas significativas en cuanto a la abundancia entre este y los meses de  mayo (6.42 ind/100 m2), julio (7.28 ind/100 m2) y agosto (6.71 ind/100 m2). La comparación de la abundancia poblacional entre años del Pez León, registrada en el 2016 con años anteriores demuestra diferencia estadística entre los años 2013 (p<0.001) y 2012 (p<0.01).
Checklist of the centipedes (Chilopoda) of Hispaniola
Authors: Martínez-Muñoz Carlos A. , Perez-Gelabert Daniel E.
Published: May 2019

Ten years have passed since the last checklist of Hispaniolan Chilopoda was done and the last bibliographic compendium was published. In this work we expand the former list of species and bibliography, update the taxonomic classification and provide an assessment on Chilobase records. A new intensive literature review was performed and both recent and formerly overlooked myriapodological works were included. The treatment of supraspecific taxonomic ranks was updated and follows Chilobase 2.0. This catalogue lists 4 fossil taxa as well as 24 extant species of centipedes from Hispaniola, 9 of which are endemic. For each extant species considered, there is information on Hispaniolan synonymies and geographic distribution. Included are some clarifications on synonymies and locality problems, and species with uncertain taxonomic status are indicated. Chilobase 2.0 was tested for completeness and accuracy. We propose several updates, grouped by incorrect species records, records not  backed by known literature and species not under their currently accepted synonym. We also recommend chilopodologists to maintain active collaboration and send their updates to this useful database.
The vulnerability of leaflitter ants to forest disturbances in the island of Puerto Rico, Greater Antilles
Authors: García Miguel A.
Published: May 2019

Reduced biodiversity and high number of endemics characterize island ecosystems. Island natives and endemics are considered more vulnerable than continental species to exotic species invasions and habitat changes. The effect of replacing a native forest by an exotic wood plantation was studied on the assemblage of native and endemic ant species. The main hypothesis was that endemic and native ant species were more vulnerable to habitat changes than the exotic ant species. Nevertheless, it was found that native ants were more numerous and specious in both native and exotic plantations. Also, high numbers of two endemic ants were detected within exotic plantations, while only one exotic ant Hypoponera opacipeps was relatively abundant, particularly on native forest. In conclusion, exotic ant species did not dominate the communities studied nor the native and endemic ant assemblages seemed to be affected negatively by the forest replacement.
Citizen science enables a new locality record for a critically endangered toad, Peltophryne Florentinoi Moreno & Rivalta, 2007
Authors: Díaz Luis M. , Lemm Jeffrey M. , Briggs Erick M. , Clark Sharon , Dannenberg Andrew L. , Gamber Russell G. , Kelly Jane , Laughlin Patrick , Markowski Gary , Shelley Erin L. , Van Bakel Adrian B.
Published: May 2019

The Zapata Toad (Peltophryne florentinoi) is reported from a new locality, Guajimico, which extends the distribution of this species to the Cienfuegos Province, in the central region of Cuba.
Inventario de las arañas (Arachnida: Araneae) de la Reserva Ecológica Limones-Tuabaquey, Sierra De Cubitas, Camagüey, Cuba
Authors: Alayón García Giraldo , Sánchez-Ruiz Alexander , Martín Castejón Yulianis , Ramírez Ruiz Maylen , Cala Riquelme Franklin
Published: May 2019

Se realiza un inventario rápido de las arañas de la Reserva Ecológica Limones-Tuabaquey, Sierra de Cubitas, Camagüey, Cuba. En total, se registran para el área protegida 71 especies, agrupadas en 59 géneros y 26 familias. Se registra por primera vez para Cuba y las Antillas Mayores la especie Homalometa nigritarsi Simon, 1897 (Tetragnathidae) y se amplia además la distribución conocida de cinco especies: Ariamnes mexicanus Exline y Levi, 1962, Anisaitis squamata Bryant, 1940 (Salticidae), Scytodes blanda Bryant, 1940 (Scytodidae), Theridion antillanum Simon, 1894 (Theridiidae) y Episinus gratiosus Bryant, 1940 (Theridiidae). Se determinan 17 especies endémicas, las cuales se consideran objetos de conservación del área protegida, particularmente Anisaitis squamata Bryant, 1940 y Scytodes blanda Bryant, 1940; especies raras que sólo se conocen de pocas localidades en el archipiélago cubano.