bluuebunny/crossref_metadata_2025 huggingface dataset:
Carbon Dioxide As a Standard of Care for Zero Contrast Interventions: When, Why and How?
Authors: Bisdas Theodosios , Koutsias Stylianos
Published: November 2019

Background:

Traditional contrast media containing iodine remain the gold standard for vessel visualization
during endovascular procedures. On the other hand, their use has several side effects and implications and
may cause contrast medium-induced nephropathy. Carbon dioxide (CO2) angiography is an old alternative technique
used only for critical patients in order to prevent kidney damages or allergic reactions.

Zero contrast procedure:

The availability of automated CO2 injectors has led to an increase in the use of CO2
angiography, providing an option for zero contrast interventions, preserving patient renal function and saving
costs for the hospital facility. Taking advantage of the properties of CO2 gas, it is possible to improve the performance
of some complex procedures such as atherectomy and the detection of type II endoleaks after EVARs.
However, a learning curve is needed to get good imaging, and learn about the qualities and limitations of the
technique.

Conclusions:

The use of automatic delivery systems for CO2 angiography appears to be a good choice for the use
of CO2 as the first imaging option. The standardization of injection protocols and the extensive use of this technique
could lead to significant benefits both for the patient's prospects and health facilities.
Approach to Neurotoxicity using Human iPSC Neurons: Consortium for Safety Assessment using Human iPS Cells
Authors: Shirakawa Takafumi , Suzuki Ikuro
Published: November 2019

Neurotoxicity, as well as cardiotoxicity and hepatotoxicity, resulting from administration of a test article is considered a major adverse effect both pre-clinically and clinically. Among the different types of neurotoxicity occurring during the drug development process, seizure is one of the most serious one. Seizure occurrence is usually assessed using in vivo animal models, the Functional Observational Battery, the Irwin test or electroencephalograms. In in vitro studies, a number of assessments can be performed using animal organs/cells. Interestingly, recent developments in stem cell biology, especially the development of Human-Induced Pluripotent Stem (iPS) cells, are enabling the assessment of neurotoxicity in human iPS cell-derived neurons. Further, a Multi-Electrode Array (MEA) using rodent neurons is a useful tool for identifying seizure-inducing compounds. The Consortium for Safety Assessment using Human iPS Cells (CSAHi; http://csahi.org/en/) was established in 2013 by the Japan Pharmaceutical Manufacturers Association (JPMA) to verify the application of human iPS cell-derived neuronal cells to drug safety evaluation. The Neuro Team of CSAHi has been attempting to evaluate the seizure risk of compounds using the MEA platform. Here, we review the current status of neurotoxicity and recent work, including problems related to the use of the MEA assay with human iPS neuronal cell-derived neurons, and future developments.
Urea Transporters Identified as Novel Diuretic Drug Targets
Authors: Li Min , Zhang Shun , Yang Baoxue
Published: November 2019

Background:

Urea Transporters are a family of membrane channel proteins that facilitate
the passive transport of urea across the plasma membrane. UTs are divided into two subgroups, UT-A
and UT-B. UT-As are primarily located in renal tubule epithelia and UT-Bs are highly expressed in
renal descending vasa recta and extrarenal multiple tissues. Various urea transporter knockout mice
exhibit low urine concentrating ability, which suggests that UTs are novel diuretic targets. With highthroughput
screening of small molecule drug-like compound libraries, various potent UT inhibitors
with IC50 at nanomolar level were identified. Furthermore, selective UT inhibitors exhibit diuretic activity
without disturbing electrolyte and metabolism balance, which confirms the potential of UTs as
diuretic targets and UT inhibitors as novel diuretics that do not cause electrolyte imbalance.

Objective:

This review article summarizes the identification and validation of urea transporter as a potential
diuretic target and the discovery of small molecule UT inhibitors as a novel type of diuretics.

Conclusion:

UTs are a potential diuretic target. UT inhibitors play significant diuresis and can be developed
to diuretics without disturbing electrolyte balance.
Alzheimer’s Disease: A Contextual Link with Nitric Oxide Synthase
Authors: Dubey Harikesh , Gulati Kavita , Ray Arunabha
Published: November 2019

Nitric oxide (NO) is a gasotransmitter with pleiotropic effects which has made
a great impact on biology and medicine. A multidimensional neuromodulatory role of NO
has been shown in the brain with specific reference to neurodegenerative disorders like
Alzheimer’s disease (AD) and cognitive dysfunction. It has been found that NO/cGMP
signalling pathway has an important role in learning and memory. Initially, it was
considered that indirectly NO exerted neurotoxicity in AD via glutamatergic excitotoxicity.
However, considering the early development of cognitive functions involved in the
learning memory process including long term potentiation and synaptic plasticity, NO
has a crucial role. Increasing evidence uncovered the above facts that isoforms of NOS
viz endothelial NO synthase (eNOS), neuronal NO synthase (nNOS) and inducible NO
synthase (iNOS) having a variable expression in AD are mainly responsible for learning
and memory activities. In this review, we focus on the role of NOS isoforms in AD
parallel to NO. Further, this review provides convergent evidence that NO could provide
a therapeutic avenue in AD via modulation of the relevant NOS expression.
Characteristics of Gamblers Who Use the French National Problem Gambling Helpline and Real-Time Chat Facility: Longitudinal Observational Study
Authors: Darbeda Stéphane , Aubin Henri-Jean , Lejoyeux Michel , Luquiens Amandine
Published: November 2019

Background

Problem gambling is a growing public health issue that is characterized by low rates of face-to-face help seeking. Helplines and real-time chat services could reduce shortfalls in treatment.

Objective

This study aimed to (1) describe the characteristics of gamblers contacting a government-funded help service, (2) study the evolution of their characteristics over time, (3) evaluate the differences between subgroups (ie, gender, media used for gambling, and media used to contact the service), and (4) explore factors influencing referral to care.

Methods

From January 2011 to December 2015, a government-funded gambling helpline and real-time chat website in France received 9474 contacts from gamblers. Counselors filled in a form for each contact, collecting demographics, gambling characteristics, and referrals. Time-series analyses were performed. Univariate logistic models were used to assess differences across subgroups. A multivariate analysis was conducted to determine the variables related to an actual referral.

Results

Gamblers were predominantly men (7017/9474, 74.07%); the average age was 41 years (SD 14). Compared with the men, the women were older (mean 50.7 years, SD 14.0 vs mean 37.9 years, SD 13.0, respectively; P<.001), were more often solely offline gamblers (1922/2457, 78.23% vs 4386/7017, 62.51%, respectively; P<.001), and had different gambling patterns. Compared with helpline contacts, real-time chat contacts were more often men (124/150, 82.7% vs 3643/4881, 74.64%, respectively; P=.04), younger (mean 32.8 years, SD 12.9 vs mean 41.3 years, SD 14.3, respectively; P<.001), more often poker gamblers (41/150, 27.3% vs 592/4881, 12.13%, respectively; P<.001), and more often web-based gamblers (83/150, 55.3% vs 1462/4881, 29.95%, respectively; P<.001). Referral was positively associated with betting (adjusted odds ratio [aOR] 1.46, 95% CI 1.27-1.67; P<.001), casino gambling (aOR 1.38, 95% CI 1.21-1.57; P<.001), scratch cards (aOR 1.83, 95% CI 1.58-2.12; P<.001), poker gambling (aOR 1.35, 95% CI 1.14-1.61; P<.001), lottery (aOR 1.27, 95% CI 1.03-1.56; P=.03), weekly gambling (aOR 1.73, 95% CI 1.40-2.15; P<.001), request for referral (aOR 17.76, 95% CI 14.92-21.13; P<.001), and a history of suicide attempts (aOR 2.13, 95% CI 1.51-3.02; P<.001), and it was negatively associated with web-based gambling (aOR 0.86, 95% CI 0.75-0.98; P=.030) and refusal to be referred (aOR 0.35, 95% CI 0.26-0.49; P<.001).

Conclusions

The governmental helpline and chat contacts included a broad range of sociodemographic profiles. Compared with the helpline, real-time chat exchanges reached a younger population of web-based gamblers, which was the target population. The development of the gambling helpline and help online website is a considerable challenge for the future.
A Weekly, Evidence-Based Health Letter for Caregivers (90Second Caregiver): Usability Study
Authors: Milios Athena , McGrath Patrick , Baillie Hannah
Published: November 2019

Background

Informal caregivers are family members or close friends who provide unpaid help to individuals with acute or chronic health conditions so that they can manage daily life tasks. The greatest source of health information is the internet for meeting the needs of caregivers. However, information on the internet may not be scientifically valid, it may be written in language that is difficult to read, and is often in very large doses. 90Second Caregiver is a health letter whose aim is to disseminate knowledge to caregivers in a user-friendly, weekly format, in order to improve their wellbeing.

Objective

The main objective was to test a sample of 90Second Caregiver health letters in order to assess their usability and to optimize the design and content of the health letters.

Methods

Usability research themes were assessed using semi-structured phone interviews, incorporating the Think Aloud method with retrospective questioning.

Results

Usability was assessed in the context of five main themes: understandability and learnability, completeness, relevance, and quality and credibility of the health letter content, as well as design and format. Caregivers generally provided positive feedback regarding the usability of the letters. The usability feedback was used to refine 90Second Caregiver in order to improve the design and content of the series. Based on the results of this study, it may be of maximum benefit to target the series towards individuals who are new to caregiving or part-time caregivers, given that these caregivers of the sample found the letters more useful and relevant and had the most positive usability experiences.

Conclusions

The findings assisted in the improvement of the 90Second Caregiver template, which will be used to create future health letters and refine the letters that have already been created. The findings have implications for who the 90Second Caregiver series should be targeting (ie, newer or part-time caregivers) in order to be maximally impactful in improving mental health and wellbeing-related outcomes for caregivers, such as self-efficacy and caregiving knowledge. The results of this study may be generalizable to the examination of other electronic health information formats, making them valuable to future researchers testing the usability of health information products. In addition, the methods used in this study are useful for usability hypothesis generation. Lastly, our 90Second delivery approach can generate information useful for a set of similar products (eg, weekly health letters targeted towards other conditions/populations).
The Adoption of a Virtual Reality–Assisted Training System for Mental Rotation: A Partial Least Squares Structural Equation Modeling Approach
Authors: Chang Chen-Wei , Yeh Shih-Ching , Li Mengtong
Published: November 2019

Background

Virtual reality (VR) technologies have been developed to assist education and training. Although recent research suggested that the application of VR led to effective learning and training outcomes, investigations concerning the acceptance of these VR systems are needed to better urge learners and trainees to be active adopters.

Objective

This study aimed to create a theoretical model to examine how determining factors from relevant theories of technology acceptance can be used to explain the acceptance of a novel VR-assisted mental rotation (MR) training system created by our research team to better understand how to encourage learners to use VR technology to enhance their spatial ability.

Methods

Stereo and interactive MR tasks based on Shepard and Metzler’s pencil and paper test for MR ability were created. The participants completed a set of MR tasks using 3D glasses and stereoscopic display and a 6-degree-of-freedom joystick controller. Following task completion, psychometric constructs from theories and previous studies (ie, perceived ease of use, perceived enjoyment, attitude, satisfaction, and behavioral intention to use the system) were used to measure relevant factors influencing behavior intentions.

Results

The statistical technique of partial least squares structural equation modeling was applied to analyze the data. The model explained 47.7% of the novel, VR-assisted MR training system’s adoption intention, which suggests that the model has moderate explanatory power. Direct and indirect effects were also interpreted.

Conclusions

The findings of this study have both theoretical and practical importance not only for MR training but also for other VR-assisted education. The results can extend current theories from the context of information systems to educational and training technology, specifically for the use of VR-assisted systems and devices. The empirical evidence has practical implications for educators, technology developers, and policy makers regarding MR training.
Ecological Momentary Assessment Within a Digital Health Intervention for Reminiscence in Persons With Dementia and Caregivers: User Engagement Study (Preprint)
Authors: Potts Courtney , Bond Raymond , Ryan Assumpta , Mulvenna Maurice , McCauley Claire , Laird Elizabeth , Goode Deborah
Published: November 2019

BACKGROUND

User-interaction event logs provide rich and large data sets that can provide valuable insights into how people engage with technology. Approaches such as ecological momentary assessment (EMA) can be used to gather accurate real-time data in an individual’s natural environment by asking questions at any given instant.

OBJECTIVE

The purpose of this study was to evaluate user engagement and responses to EMA questions using InspireD, an app used for reminiscence by persons with dementia and their caregivers. Research findings can be used to inform EMA use within digital health interventions.

METHODS

A feasibility trial was conducted in which participants (n=56) used the InspireD app over a 12-week period. Participants were a mean age of 73 (SD 13) and were either persons with dementia (n=28) or their caregivers (n=28). Questions, which they could either answer or choose to dismiss, were presented to participants at various instants after reminiscence with personal or generic photos, videos, and music. Presentation and dismissal rates for questions were compared by hour of the day and by trial week to investigate user engagement.

RESULTS

Overall engagement was high, with 69.1% of questions answered when presented. Questions that were presented in the evening had the lowest dismissal rate; the dismissal rate for questions presented at 9 PM was significantly lower than the dismissal rate for questions presented at 11 AM (9 PM: 10%; 11 AM: 50%; χ21=21.4, P<.001). Questions asked following reminiscence with personal media, especially those asked after personal photos, were less likely to be answered compared to those asked after other media. In contrast, questions asked after the user had listened to generic media, in particular those asked after generic music, were much more likely to be answered.

CONCLUSIONS

The main limitation of our study was the lack of generalizability of results to a larger population given the quasi-experimental design and older demographic where half of participants were persons with dementia; however, this study shows that older people are willing to participate and engage in EMA. Based on this study, we propose a series of recommendations for app design to increase user engagement with EMA. These include presenting questions no more than once per day, after 8 PM in the evening, and only if the user is not trying to complete a task within the app.
An Electronic Clinical Decision Support System for the Management of Low Back Pain in Community Pharmacy: Development and Mixed Methods Feasibility Study (Preprint)
Authors: Downie Aron Simon , Hancock Mark , Abdel Shaheed Christina , McLachlan Andrew J , Kocaballi Ahmet Baki , Williams Christopher M , Michaleff Zoe A , Maher Chris G
Published: November 2019

BACKGROUND

People with low back pain (LBP) in the community often do not receive evidence-based advice and management. Community pharmacists can play an important role in supporting people with LBP as pharmacists are easily accessible to provide first-line care. However, previous research suggests that pharmacists may not consistently deliver advice that is concordant with guideline recommendations and may demonstrate difficulty determining which patients require prompt medical review. A clinical decision support system (CDSS) may enhance first-line care of LBP, but none exists to support the community pharmacist–client consultation.

OBJECTIVE

This study aimed to develop a CDSS to guide first-line care of LBP in the community pharmacy setting and to evaluate the pharmacist-reported usability and acceptance of the prototype system.

METHODS

A cross-platform Web app for the Apple iPad was developed in conjunction with academic and clinical experts using an iterative user-centered design process during interface design, clinical reasoning, program development, and evaluation. The CDSS was evaluated via one-to-one user-testing with 5 community pharmacists (5 case vignettes each). Data were collected via video recording, screen capture, survey instrument (system usability scale), and direct observation.

RESULTS

Pharmacists’ agreement with CDSS-generated self-care recommendations was 90% (18/20), with medicines recommendations was 100% (25/25), and with referral advice was 88% (22/25; total 70 recommendations). Pharmacists expressed uncertainty when screening for serious pathology in 40% (10/25) of cases. Pharmacists requested more direction from the CDSS in relation to automated prompts for user input and page navigation. Overall system usability was rated as excellent (mean score 92/100, SD 6.5; 90th percentile compared with similar systems), with acceptance rated as good to excellent.

CONCLUSIONS

A novel CDSS (high-fidelity prototype) to enhance pharmacist care of LBP was developed, underpinned by clinical practice guidelines and informed by a multidisciplinary team of experts. User-testing revealed a high level of usability and acceptance of the prototype system, with suggestions to improve interface prompts and information delivery. The small study sample limits the generalizability of the findings but offers important insights to inform the next stage of system development.
Stunting Diagnostic and Awareness: Impact assessment study of sociodemographic factors of stunting among school-going children of Pakistan (Preprint)
Authors: Ponum Mahvish , Khan Saadia , Hasan Osman , Mahmood Muhammad Tahir , Abbas Asad , Iftikhar Mehwish , Arshad Reema
Published: November 2019

BACKGROUND

Stunting is a major public health issue in most of developing countries. Although, its worldwide prevalence is decreasing slowly but the number of stunted children is still rising in Pakistan. Stunting is highly associated with several long-term consequences, including higher rate of mortality and morbidity, deficient cognitive growth, school performance, learning capacity, work capacity and work productivity. To prevent stunting, we proposed Stunting Diagnostic and Education app. This app includes detailed knowledge of stunting and it’s all forms, symptoms, causes, video tutorials and guidelines by the Pediatricians and Nutritionists.

OBJECTIVE

The aim and objective of this study is to assess the prevalence of stunting in school-going children in Multan District of Punjab Pakistan and to analyze the risk factors associated with stunting in children under and over 5 age. This study presents Stunting Diagnostic and Education app to prevent the stunting in children under 5 age and children over 5 age (where required).

METHODS

A cross-sectional study has been conducted in schools of Multan District, Pakistan for the period of January 2019 to June 2019. Sample data of 1420 children, aged 4 to 18 years using three age groups, were analyzed by using SPSS version 21.0 to assess the prevalence of stunting and to analyze the main factors associated with it. Chi square test was applied in comparison with rural and urban participants and p-value <0.05 was considered as significant. This study includes distribution of sociodemographic characteristics, parental education, working status of mothers, dietary patterns of school going children and prevalence of stunting in school going children. After getting study results, Stunting Diagnostic and Education app was developed according to the instructions of child experts and nutritionists.

RESULTS

354 (24.93%) participants were stunted out of 1420, 11.9 % children were obese and 63.17% children were normal. Out of 354 stunted children, higher ratio of stunting was found in the age group of 8-11 years children with 51.98 percentage. 37.85% stunted children were found in the age group of 4-7 years and 10.17% stunting was found in the age group of 12-18 years children. It was observed in the study that male children were highly stunted than female with 57.91 % and 42.09% respectively. Children living in rural areas were more stunted affected as compared to the children living in urban society with percentage 58.76 and 41.24 respectively.

CONCLUSIONS

Our study concluded that 24.93% children were stunted, out of which, age group of 8-11 years children were highly stunted. The study showed that the literacy of mother or caregiver had high impact on children’s health. Therefore, Stunting Diagnostic and Education app was developed to educate mothers to prevent stunting.
Screening for Hearing Impairment in Older Adults by Smartphone-Based Audiometry, Self-Perception, HHIE Screening Questionnaire, and Free-Field Voice Test: Comparative Evaluation of the Screening Accuracy With Standard Pure-Tone Audiometry (Preprint)
Authors: Li Lok Yee Joyce , Wang Shin-Yi , Wu Cheng-Jung , Tsai Cheng-Yu , Wu Te-Fang , Lin Yaoh-Shiang
Published: November 2019

BACKGROUND

Hearing impairment is the most frequent sensory deficit in humans, affecting more than 360 million people worldwide. In fact, hearing impairment is not merely a health problem, but it also has a great impact on the educational performance, economic income, and quality of life. Hearing impairment is therefore an important social concern.

OBJECTIVE

We aimed to evaluate and compare the accuracy of self-perception, Hearing Handicap Inventory for the Elderly-Screening (HHIE-S) questionnaire, free-field voice test, and smartphone-based audiometry as tests for screening moderate hearing impairment in older adults in China.

METHODS

In this study, 41 patients were recruited through a single otology practice. All patients were older than 65 years. Patients with otorrhea and cognitive impairment were excluded. Moderate hearing impairment was defined as mean hearing thresholds at 500, 1000, 2000, and 4000 Hz >40 dB hearing loss (pure-tone average > 40 dB hearing loss). All patients completed 5 hearing tests, namely, the self-perception test, HHIE-S questionnaire test, free-field voice test, smartphone-based audiometry test, and standard pure-tone audiometry by the same audiologist. We compared the results of these tests to the standard audiogram in the better-hearing ear.

RESULTS

The sensitivity and the specificity of the self-perception test were 0.58 (95% CI 0.29-0.84) and 0.34 (95% CI 0.19-0.54), respectively. The sensitivity and the specificity of the HHIE-S questionnaire test were 0.67 (95% CI 0.35-0.89) and 0.31 (95% CI 0.316-0.51), respectively. The sensitivity and the specificity of the free-field voice test were 0.83 (95% CI 0.51-0.97) and 0.41 (95% CI 0.24-0.61), respectively. The sensitivity and the specificity of the smartphone-based audiometry test were 0.92 (95% CI 0.60-0.99) and 0.76 (95% CI 0.56-0.89), respectively. Smartphone-based audiometry correctly diagnosed the presence of hearing loss with high sensitivity and high specificity.

CONCLUSIONS

Smartphone-based audiometry may be a dependable screening test to rule out moderate hearing impairment in the older population.
Tolerance of T2 Generation ‘Kitaake’ Rice (Oryza sativa L.) CRISPR/Cas9-OsGA20ox-2 Mutant Strains to Drought Condition
Authors: Mubarok Husni , Basunanda Panjisakti , Santoso Tri Joko
Published: November 2019

Rice (Oryza sativa L.) is important staple crop in Indonesia. Food demand that continues to rise while inadequate land could be managed by assembling superior cultivar using CRISPR-Cas9 system method. Editing the genome by mutating the GA20ox-2 gene could improve both crop yield and ability to thrive in marginal land (drought). This experiment aims to obtain non-transgenic mutant plants (non Cas9 and hpt genes), gain information on GA20ox-2 gene expression levels, and study the tolerance levels of the CRISPR /Cas9-OsGA20ox-2 mutant lines 'Kitaake' T2 generation against drought conditions. Planting material using a mutant gene GA20ox 2 ‘Kitaake’ (K23.1, K15, K29.1, K19.1) and wild-type comparison. From 20 plants, respectively the K23.1, K15, K29.1, and K19.1 lines have 50%, 50%, 0%, and 45% of non-transgenic plants. DNA mutations in the form of deletion 44 bases (K23.1, K29.1, K19.1) and insertion of two bases (K15) are transcribed into RNA. The transcription results in a number of lower amino acids compare to its wild type (389 amino acids). The lines K23.1, K29.1, K19.1 have 373 amino acids and the K15 line has 300 amino acids (frameshift). Differences in the number of amino acids result in different phenotypic expressions. K15 mutant line has lower plant height and leaf length than the other mutant lines and wild type. The decrease does not decrease the potential of the crop. Mutations in the K15 line did not indicate better tolerant response to drought stress than other mutant lines and wild type in both vegetative and generative phase.
The Growth, Production, and Quality of Shallot at Inland Quartz Sands (Quarzipsamments) in the off Season
Authors: Firmansyah Anang , Bhermana Andy
Published: November 2019

The development of shallot cultivation at back quartz sand during rainy or off season  can be considered as new innovation. The objectives of this study is to obtain shallot varieties that are adaptive in terms of the growth, production, and quality parameters. The research was conducted during off season in Palangkaraya. The experimental design used in this research is randomized block design (RBD) 4x3 with 4 treatments of varieties (Maja Cipanas, Tajuk, Bauji and Bima Brebes), and 3 replication for each treatment. The results showed that soil bulk density increased with the deepening of the soil, however soil water content decreased. Based on growth parameter, Tajuk showed the best results and significantly different comparing to Bima Brebes, with plant height consecutively 46.88 cm and 39.52 cm, number of leaves 70.7 and 35.27  and number of shoot 13.43 and 6.60. For production parameter, the weight of varieties of Maja Cipanas, Bauji dan Bima Brebes is 10 grams more than Tajuk with weight is 6,97 grams only. The produstion of Tajuk is low and not significantly different from Bima Brebes, with production is respectively 15.28 ton/ha and 13.31 ton/ha, while the varieties of Bauji showed the highest dry production of 22.4 ton/ha although it is not significantly different with Maja Cipanas that can produce 18.49 ton/ha. For quality parameter,  the varieties of Bima Brebes showed the optimum results in terms of parameter of hardness of tubers and total dissolved solids (TDS) with the value of 4.9 kg /cm2 and 16,42 % respectively.
THE VALUE OF FOOD BEHAVIOR OF THE MILITARY FOR IMPROVEMENT OF THE FOOD SERVICE SYSTEM IN THE ARMED FORCES AND THE NAVY OF THE RUSSIAN FEDERATION
Authors: Lopatina V. F. , Lopatin S. A. , Kuznetsov S. M. , Novoselov S. A.
Published: November 2019

Eating behavior is a selection of definite food subconsciously aimed at meeting physiological needs from main nutrients and energy. Genetic aspects of human metabolism as well as various environmental factors including social-psychological factors have a significant impact on the appearance and a further retention of definite food excesses of each person. Healthy lifestyle promotion (including compliance with nutrition prescription, preference to balanced daily rations cor responding with the level of daily energy needs) helps to form human eating behavior based on nutrition laws that promotes preservation and strengthening of public health (the military personnel). Formation of proper eating behavior may become an important preventive measure for preservation and strengthening of the health of the military personnel of the Armed Forces of the Russian Federation and the Navy of the Russian Federation. Increasing of daily energy needs due to introduction of new model of physical fitness in the Armed Forces of the Russian Federation exerts a considerable impact on an eating behavior in the military personnel. Correction of an eating behavior in the military draft servicemen in the Armed Forces of the Russian Federation as well as observance of the principles of healthy nutrition may be conducted by means of outreach interviews with specified cohort. Possible changes in eating behavior may be monitored using special tests and questionnaires allowing to execute its overall assessment. Dynamic assessment of eating behavior may take rightful place in the system of scientific study of lifestyle of the military and also be in active use on further improvement of food service system of the Armed Forces of the RF and the Navy of the RF. Significance of assessment of eating behavior in the military will not be irrelevant in the near future but, to the contrary, will gradually increase in connection with advances in science, promotion of food fit to personal genetic aspects and improvement of food service system of the Army Forces of the RF.
HISTORY OF MILITARY TRAINING IN CRIMEAN MEDICAL ACADEMY NAMED AFTER S. I. GEORGIEVSKY
Authors: Ivanova N. V. , Kutsenko S. N. , Astapenko V. P. , Kudinov V. V. , Malchenko A. G.
Published: November 2019

The present paper represents main periods of military and medical training in the Crimean Medical University named after S. I. Georgievsky from 1945 to 2010. The first period (1945–1970). Training of army medical officers for Army Forces was carried out at the Military Arts Division. In 1960, due to reduction in Army Forces by 1200000 servants the division was dissolved. From 1960 to 1968, training in Crimean Medical Institute was not conducted. In 1968, the Military Arts Division was restored and to 1970, the training of army medical officers for Army Forces was continued. The second period (1970–1991). In 1970, the Naval Division was found and training of surgeons for the Navy was started. The third period (1991–2010). The Naval Division was renamed in the Military Arts Division where training of army medical officers for Army Forces was started. The division was further changed its name twice to the Division of Extreme and Military Medicine and the Division of Disaster Medicine. In 2010, the government of Ukraine made a decision regarding cutbacks of the Division of Disaster and Military Medicine in the Crimean Medical University. In the same year, the last graduation of army medical officers was held. Throughout the military training period, of the more than 7000 graduates of the Crimean Medical Institute (University) were certified as reserve officers of Medical Service for the Navy and of the more than 8000 graduates — as reserve officers of Medical Service for the Armed Forces.
Comparative analysis of the selected land consolidation projects
Authors: Atkoceviciene Virginija , Jukneliene Daiva , Valciukiene Jolanta , Orechovaite Diana
Published: November 2019

Land consolidation is an important stage for agriculture and rural development. During the land reform, parcels of irrational size and shape were formed, which became difficult to cultivate efficiently. In essence, land consolidation projects must primarily be developed in areas with large, viable farms, and land parcels forming land holdings are not compact, distant from each other and from centers. Land consolidation projects have been under development for many years, but it is appropriate to pay attention to the expediency of implemented projects. Land consolidation goals and procedures vary from country to country, as the development of this procedure in each country is determined by historical trends, culture, traditions and land consolidation legislation. Many of those who have analyzed this topic emphasize the need for consolidation, but it is very important that landowners understand the importance of this process and make sure of its opportunities and benefits. Land consolidation must be designed so that the benefits of the project are higher than the results of the conversion works before the project. The purpose of this article is to compare land consolidation projects which were prepared in different areas of Lithuania. Two objects of the research in which land consolidation projects had been carried out and implemented in 2013 were selected, where the number of sites in units decreased: 41.8% in one project and 28% in the other. Changes in parcel configuration were also noticeable, when in one of the projects analyzed even 92 percent of land parcels have become regular - close to rectangular - shapes. The average size of land parcels in this project increased from 5.32 ha to 9.14 ha.
Places to sit for senior citizens located in urban space: Warsaw city as a case study
Authors: Skibińska Maja , Denis Małgorzata , Wieczorek Mariusz
Published: November 2019

Ławki to meble miejskie, które gwarantują komfort wszystkim użytkownikom, co jest ważne zwłaszcza w kontekście potrzeb starzejących się społeczeństw. Ich lokalizacja, liczba i konstrukcja mają ogromne znaczenie. Niniejszy artykuł opiera się na wynikach projektów badawczych dotyczących ławek miejskich w przestrzeni publicznej Warszawy. Zakres merytoryczny opracowania obejmuje identyfikację bieżących problemów związanych z miejscami do siedzenia na obszarach miejskich oraz związanych z nimi potrzeb osób starszych. Zgodnie z wynikami badań ławki powinny mieć oparcie lub oparcie i podłokietniki, być umieszczone w regularnych odstępach, w pobliżu miejsca zamieszkania i punktów handlowo-usługowych. Niniejszy artykuł stanowi wkład w dyskusję na temat kształtowania przestrzeni publicznej, która jest wygodna dla seniorów.
Landscape forms in the architecture of waste management facilities in cities
Authors: Wowrzeczka Bogusław
Published: November 2019

Obiekty architektoniczne i budowle inżynierskie naśladujące w sposób rzeczywisty lub wyobrażony naturę opierają się na wzorcach spotykanych w naturalnym krajobrazie. W miastach sztuczne krajobrazy stały się istotnym elementem innowacyjnych koncepcji ekologicznych zmierzających do renaturyzacji środowiska miejskiego. Dokonano przeglądu przykładów architektury obiektów związanych z przetwarzaniem, recyklingiem i ze składowaniem odpadów oraz zaklasyfikowano je do trzech typów sztuczności natury, które reprezentują: kontynuujący naturę, naśladujący naturę i sugerujący naturę. W artykule przedstawiono badanie, w jaki sposób architekci sztucznych krajobrazów poszukując nowych rozwiązań, inspirowani są rzeczywistymi modelami natury oraz w jaki sposób je przekształcają, tworząc innowacyjne rozwiązania obiektów przemysłowych w środowisku miejskim.
Decomposition mechanism of dihydroxylammonium 5,5'-bis(tetrazole)-1,1'-diolate on Al(111) surface by periodic DFT calculation
Authors: Zhao Ying , Xing Xiaoling , Zhao Shengxiang , Ju Xuehai
Published: November 2019

The generalized gradient approximation (GGA) of density function theory (DFT) methods are employed to investigate the decomposition of TKX- -50 molecule on the Al(111) surface. The calculation employs an Al supercell slab model and periodic boundary conditions. Five kinds of adsorption configurations for TKX-50 on Al surface are studied. The TKX-50 is adsorbed on Al surface to form the N?Al, O?Al and OH?Al bonds. The adsorption energies are in the range from ?113.15 to ?1334.40 kJ/mol. The activation energies of all configurations are in the range of 100.34?354.10 kJ/mol. The N1-N2 ruptures in V1 and N2-N3 ruptures in V2 takes place easily. The activation energies of these two bonds rupture (100.34 and 108.06 kJ/mol, respectively) are less than that of pure TKX-50 (161.58 and 215.99 kJ/mol). Al atoms promote the breaking of the tetrazole ring of TKX-50. The quantities of electron transfer from Al atoms to TKX-50 are in range of 1.42?4.90 e.
Relationship between the frequency of falls, fear of falling and functional abilities in women aged 65 and over
Authors: Ivanovic Suncica , Trgovcevic Sanja , Kocic Biljana , Tomasevic-Todorovic Snezana , Jeremic-Knezevic Milica , Knezevic Aleksandar
Published: November 2019

Background/Aim. An increased tendency to fall and subsequent occurrence of injuries due to decline in the functional abilities are some of the many problems in older persons. The aim of the study was t o determine the differences in functional abilities and the expressiveness of fear of falling be-tween the women aged 65 and over who experienced a fall in the past 12 months (G1) and those that did not (G2). Methods. In this cross-sectional study, 236 women aged 65 and over were included. Fall history was based on self?reporting, the fear of a fall was estimated based on The Falls Efficacy Scale International ? FESI, while the functional ability was measured by The Lawton Instrumental Activities of Daily Living ? IADL. Results. Just under half of the women in the sample reported that one or more falls occurred in the last 12 months. Through the connectivity analysis, in both groups (G1 and G2), coefficients of correlation achieved statistical significance between the functional ability and fear of falling. A strong and negative correlation between IADL and FESI score in both groups, G1 (? = -0.695; p < 0.001) and G2 (? = -0.657; p < 0.001), was confirmed. Conclusion. The improvement of functional ability in women aged 65 and over could lower the risk of falling in this population.
Centre for Health Record Linkage
Authors: Irvine Katie , Hall Rick , Taylor Lee
Published: November 2019

ContextThe Centre for Health Record Linkage (CHeReL) was established in 2006 as a dedicated health and human services data linkage facility for two Australian jurisdictions, New South Wales and the geographically-nested Australian Capital Territory. The two jurisdictions have their own Governments and separate Health and Human Service systems.
Purpose and OperationsThe primary purpose of the CHeReL is to make linked administrative and routinely collected healthdata available to researchers and government within relevant regulatory and governance frameworks.The CHeReL’s data governance and technical operations draw on international best practice andhave been refined by learnings from other data linkage centres.
OutcomesOver twelve years of operation, more than 2,320 unique investigators from 140 institutions haveused the CHeReL, producing 615 publications in peer-reviewed literature. A robust pipeline of newdevelopment is expected to further amplify the use of linked data for cutting edge medical researchand support a vision of data-informed policy and data-driven government services.
Abordagem multiprofissional na Promoção da Saúde: o contexto de olhares, profissional, e do sujeito do cuidar
Authors: Silva Luzia Wilma Santana da , Almeida Mauricio Andrade , Squarcini Camila Fabiana Rossi , Silva Juciara De Santana , Pires Eulina Patrícia Oliveira Ramos , Novaes Isabela Gonçalves
Published: November 2019

Objetivou-se avaliar a abordagem multiprofissional no contexto do olhar profissional e do sujeito da ação do cuidar de um programa de atividade física regular. Como metodologia, o estudo de método misto, fundamentado no modelo RE-AIM (Reach = alcance, Efficacy = eficácia, Adoption = adoção, Implementation = implementação, Maintanance = manutenção), realizado entre outubro/2015 a agosto/2016, em um município do interior da Bahia, por meio de entrevista semiestruturada com profissionais e pessoas adulto-idosas com doença crônica não transmissível, participantes de um programa de atividade física regular, e inquérito documental em prontuário de saúde. Os resultados evidenciaram os benefícios do trabalho integrador à ação social coletiva em saúde das pessoas, no processo de formação profissional e na melhoria da saúde das pessoas, impactando nos índices pressóricos, de modo à sua diminuição aos níveis limítrofes à promoção da qualidade da saúde e viver humano. Como conclusões: A promoção da qualidade de vida e saúde de pessoas em enfrentamento crônico é alavancada quando exercida através de abordagem multiprofissional e enfoque interdisciplinar, elementos necessários à potencialização de políticas públicas e programas de saúde de impacto à saúde pública.
Corporate Volunteering: a Tool for Promoting a Strategy for Internal Corporate Social Responsibility Integrating Retirees
Authors: Cosenza José Paulo , Gil María Isabel Saz , Alegría Ana Isabel Zardoya
Published: November 2019

RESUMO: Este artigo tem como objetivo realizar uma análise exploratória da efetividade da implementação de um programa de Voluntariado Corporativo voltado ao contexto dos trabalhadores aposentados das empresas, como instrumento em prol de um envelhecimento participativo e saudável. O estudo centrou-se na importância social da participação social dos aposentados em uma empresa como interesse prioritário para o desenvolvimento de programas de Voluntariado Corporativo e aprofundamento do desempenho socialmente responsável das organizações, em ações de voluntariado realizadas por seus funcionários aposentados. Os resultados mostram que o desempenho dos aposentados nas atividades de voluntariado de uma empresa pode usufruir de suportes teóricos intimamente conectados e está diretamente relacionado à Responsabilidade Social Empresarial, contribuindo para promover uma velhice ativa, saudável e justa, com benefício social para a comunidade.
Grau de dependência e funcionalidade familiar do idoso
Authors: Brito Luiza Rocha , Lopes Arianna Oliveira Santana , Oliveira Alessandra Sousa de , Reis Luciana Araújo dos , Oinhos João Paulo Quinelato
Published: November 2019

Objetivou-se avaliar o grau de dependência do idoso e sua relação com a funcionalidade familiar. Estudo exploratório, descritivo de abordagem quantitativa, realizado com 37 idosos dependentes. Verificou-se que 81,1% deles são idosos dependentes; e 51,4% apresentam uma família altamente funcional. Evidenciou-se que a maioria desses idosos apresentavam uma certa dependência e que, apesar de não ter sido identificada uma relação direta entre as variáveis estudadas, destacou-se a importância de bem compreendê-las.
Análise dos Programas de Preparação para Aposentadoria (PPA) desenvolvidos por instituições públicas brasileiras
Authors: França Lucia Helena De Freitas Pinho , Leite Soniárlei Vieira , Simões Fabrícia Prado , Garcia Thaysa , Ataliba Patrick
Published: November 2019

Este estudo objetivou analisar as características dos Programas de Preparação para a Aposentadoria (PPA), desenvolvidos por 35 gestores ou coordenadores de PPA, em igual número de instituições públicas brasileiras. Por meio de questionário, os gestores avaliaram itens como tempo de existência, metodologia, temas abordados, processo de acompanhamento e avaliação dos programas. Metade dos programas tinha até dois anos de existência; a maioria utilizava palestras, dinâmicas, vivências, workshop e coaching. Em geral, raras organizações realizavam acompanhamento e avaliações sistemáticas, especialmente para comprovar a eficácia dos programas no bem-estar dos aposentados, após saída da organização. Recomendações são fornecidas visando à sistematização, expansão e avaliação do PPA no Brasil.
Utilizing Idea Mapping to Enhance EFL College Students’ Writing Performance at Universitas Islam Negeri Maulana Malik Ibrahim Malang
Authors: Cahyono Agus Eko , , Masrokhin
Published: November 2019

Writing, among the four skills, is clearly a complex process, and being competent in writing is frequently accepted as being competent of last language skill to acquire (Nunan, 1991:91). Idea mapping refers to mind mapping which can help students to generate and organize their ideas in writing. This study attempts to investigate how can idea mapping improve the writing ability of the third semester students of English Department at Universitas Islam Negeri Maulana Malik Ibrahim Malang. The classroom action research design employed in this study is a collaborative classroom action research. The design of classroom action research utilized in this study follows that of Kemmis and McTaggart (2000:595) cited in Koshy (2007:4) which comprises four main steps, namely, planning, implementing the action, observing, and reflecting which are preceded by reconnaissance (preliminary study). The findings of the study are presented based on the result of students’ writing, observation checklists, and field notes. All the findings are about the activities done in Cycle 1 and Cycle 2. Based on the results of the students’ writing, there was a slight improvement of the students’ mean score from the previous score in the preliminary study to Cycle 1. The mean of the previous score was 46.25 and the mean score of the students’ writing in Cycle 1 was 59.69. The students’ involvement in writing activities was more than what had been stated in the criteria of success. This situation implied that the second criterion of success had not been fulfilled. Better improvement of mean score is gained from the preliminary study to the Cycle 2. The mean of the previous score in the preliminary study was 46.25 and the mean score of the students’ writing in Cycle 2 was 69.85. The improvement met the first criteria of success because there was 75% of the students who achieved the target score 65. Further, Idea mapping has revealed improving the writing ability of the third semester EFL college students at Universitas Islam Negeri Maulana Malik Ibrahim Malang. Based on the implementation of idea mapping in teaching writing, it is suggested that English teachers apply idea mapping especially in teaching writing. Besides, it is advisable for teacher to give more and various tasks to the students. To the future teacher-researchers, particularly those who are interested in applying idea mapping in their classroom research, it is suggested that they conduct classroom action research on the use of idea mapping in teaching writing related to other text types, such as narrative, procedure or recount.