bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of exposed facets and oxygen vacancies on the catalytic activity of PdxCe1−xO2−δ catalysts: a combined experimental and theoretical study
Authors: Liu Xiao , Wen Yanwei , Tang Yuanting , Lang Yun , Shan Bin , Chen Rong
Published: August 2017

The effect of exposed facets and oxygen vacancies on the catalytic activity of PdxCe1−xO2−δ nanorods has been investigated.
Mass spectrometry based identification of galectin-3 interacting proteins potentially involved in lung melanoma metastasis
Authors: Dange Manohar C. , Bhonsle Hemangi S. , Godbole Rashmi K. , More Shyam K. , Bane Sanjay M. , Kulkarni Mahesh J. , Kalraiya Rajiv D.
Published: August 2017

Workflow depicting enrichment and identification of galectin-3 interacting proteins.
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade
Authors: Pippione Agnese C. , Federico Antonella , Ducime Alex , Sainas Stefano , Boschi Donatella , Barge Alessandro , Lupino Elisa , Piccinini Marco , Kubbutat Michael , Contreras Jean-Marie , Morice Christophe , Al-Karadaghi Salam , Lolli Marco L.
Published: August 2017

Compound 4, derived from IMD-0354, blocks the canonical NF-κB pathway although it is inactive on the IKKβ enzyme.
Highly fluorescent N,S-co-doped carbon dots: synthesis and multiple applications
Authors: Shen Jie , Zhang Ting , Cai Yan , Chen Xiuying , Shang Shaoming , Li Juan
Published: August 2017

N and S co-doped carbon dots (N,S-CDs) synthesized from biomass can be used as multicolor probes for cell imaging. The N,S-CDs can selectively and sensitively detect Cr(vi) in real lake water, human serum and living cells.
18O2labeling experiments illuminate the oxidation of ent-kaurene in bacterial gibberellin biosynthesis
Authors: Nagel Raimund , Peters Reuben J.
Published: August 2017

Parallel mechanisms between independently evolved plant and bacterialent-kaurene oxidases.
Post-synthetic modification of polyvinyl alcohol with a series of N-alkyl-substituted carbamates towards thermo and CO2-responsive polymers
Authors: Kong Tengfei , Guo Guoqiang , Zhang Huatang , Gao Liang
Published: August 2017

Intensive efforts have been devoted to the synthesis of thermoresponsive polymers with terminal N-alkyl-substituted groups.
Construction of polymer coated core–shell magnetic mesoporous silica nanoparticles with triple responsive drug delivery
Authors: Hegazy Mohammad , Zhou Pei , Wu Guangyu , Wang Lei , Rahoui Nahla , Taloub Nadia , Huang Xin , Huang Yudong
Published: August 2017

Multi-responsive drug delivery systems are playing a very important role in nanomedicine, as they can feature as smart carriers releasing their payload on demand.
Macromolecular interactions and synergy in xanthan/HPAM aqueous solutions
Authors: Cai Shuwei , He Xianru , Liu Kun , Rodrigues Alisson M. , Zhang Rui
Published: August 2017

It is known that the rheological properties of a polymer solution are strongly dependent on the polymer structure, composition, conformation and interactions between the polymer and the solvent.
Thixotropic stiff hydrogels from a new class of oleoyl-d-glucamine-based low-molecular-weight gelators
Authors: Ohsedo Yutaka , Oono Masashi , Saruhashi Kowichiro , Watanabe Hisayuki , Miyamoto Nobuyoshi
Published: August 2017

A series of tripartite compounds comprising oleoyl, amino acid and d-glucamine moieties form stiff molecular hydrogels with strong thixotropic properties.
Cu-catalyzed intermolecular oxyalkylation of styrenes under air: access to diverse iminolactones
Authors: Lv Yunhe , Pu Weiya , Mao Shukuan , Ren Xiaoran , Wu Yingtao , Cui Hao
Published: August 2017

A practical, simple, and efficient copper-catalyzed oxyalkylation of styrenes with α-bromoacetamides for the synthesis of iminolactones was developed under air.
Bio nano ink for 4D printing membrane proteins
Authors: Mathews Anu Stella , Abraham Sinoj , Kumaran Surjith Kumar , Fan Jiaxin , Montemagno Carlo
Published: August 2017

Photo curable bio-nano ink was designed, developed and printed using a stereolithographic printer.
Lanthanide contraction and chelating effect on a new family of lanthanide complexes with tetrakis(O-isopropyl)methyle-nediphosphonate: synthesis, structures and terahertz time-domain spectroscopy
Authors: Ma Yan , Yang Yong-Sheng , Jiang Yu-Han , Li Yue-Xue , Liu Min , Li Zhong-Feng , Han Hong-Liang , Yang Yu-Ping , Xin Xiu-Lan , Jin Qiong-Hua
Published: August 2017

Sixteen lanthanide–diphosphate complexes have been synthesized by the reaction of lanthanide chlorides and tetrakis(O-isopropyl)methylenediphosphonate ligand in the solvent of acetonitrile (with ethanol or DMF) at room temperature.
Phosphorylcholine oligomer-grafted graphene oxide for tumor-targeting doxorubicin delivery
Authors: Qin Yu , Wang Changyu , Jiang Yun , Liu Tao , Yang Jianyong , Lin Run , Zhang Tao
Published: August 2017

Phosphorylcholine oligomer-grafted, folic acid-labeled and doxorubicin-loaded graphene oxide was found to be a potential versatile platform for biomarker-directed drug delivery with optimal biocompatibility.
Perovskites decorated with oxygen vacancies and Fe–Ni alloy nanoparticles as high-efficiency electrocatalysts for the oxygen evolution reaction
Authors: Zhu Kaiyue , Wu Tao , Li Mingrun , Lu Ruifeng , Zhu Xuefeng , Yang Weishen
Published: August 2017

Oxygen vacancies and Fe–Ni alloy nanoparticles decorated on a perovskite backbone can boost the oxygen evolution activity of perovskites.
Stacking up layers of polyaniline/carbon nanotube networks inside papers as highly flexible electrodes with large areal capacitance and superior rate capability
Authors: Dong Liubing , Liang Gemeng , Xu Chengjun , Ren Danyang , Wang Jinjie , Pan Zheng-Ze , Li Baohua , Kang Feiyu , Yang Quan-Hong
Published: August 2017

A highly flexible paper electrode with large areal capacitance and superior rate capability was prepared.
Understanding energy transfer with luminescent gold nanoclusters: a promising new transduction modality for biorelated applications
Authors: Díaz Sebastián A. , Hastman David A. , Medintz Igor L. , Oh Eunkeu
Published: August 2017

AuNCs engage in energy transfer by a non-Förster process although many of the same photophysical requirements are needed.
How to Choose Between Measures of Tinnitus Loudness for Clinical Research? A Report on the Reliability and Validity of an Investigator-Administered Test and a Patient-Reported Measure Using Baseline Data Collected in a Phase IIa Drug Trial
Authors: Hall Deborah A. , Mehta Rajnikant L. , Fackrell Kathryn
Published: August 2017

Purpose

Loudness is a major auditory dimension of tinnitus and is used to diagnose severity, counsel patients, or as a measure of clinical efficacy in audiological research. There is no standard test for tinnitus loudness, but matching and rating methods are popular. This article provides important new knowledge about the reliability and validity of an audiologist-administered tinnitus loudness matching test and a patient-reported tinnitus loudness rating.

Method

Retrospective analysis of loudness data for 91 participants with stable subjective tinnitus enrolled in a randomized controlled trial of a novel drug for tinnitus. There were two baseline assessments (screening, Day 1) and a posttreatment assessment (Day 28).

Results

About 66%–70% of the variability from screening to Day 1 was attributable to the true score. But measurement error, indicated by the smallest detectable change, was high for both tinnitus loudness matching (20 dB) and tinnitus loudness rating (3.5 units). Only loudness rating captured a sensation that was meaningful to people who lived with the experience of tinnitus.

Conclusions

The tinnitus loudness rating performed better against acceptability criteria for reliability and validity than did the tinnitus loudness matching test administered by an audiologist. But the rating question is still limited because it is a single-item instrument and is probably able to detect only large changes (at least 3.5 points).
Influence of Linguistic and Nonlinguistic Variables on Generalization and Maintenance Following Phonomotor Treatment for Aphasia
Authors: Pompon Rebecca Hunting , Bislick Lauren , Elliott Kristen , Madden Elizabeth Brookshire , Minkina Irene , Oelke Megan , Kendall Diane
Published: August 2017

Purpose

Although phonomotor treatment shows promise as an effective intervention for anomia in people with aphasia, responses to this treatment are not consistent across individuals. To better understand this variability, we examined the influence of 5 participant characteristics—age, time postonset, aphasia severity, naming impairment, and error profile—on generalization and maintenance of confrontation naming and discourse abilities following phonomotor treatment.

Method

Using retrospective data from 26 participants with aphasia who completed a 6-week phonomotor treatment program, we examined the relationships between participant characteristics of interest and change scores on confrontation naming and discourse tasks, measured pretreatment, immediately following treatment, and 3 months following treatment.

Results

Although the participant characteristics of aphasia severity and error profile appeared to predict generalization to improved confrontation naming of untrained items and discourse performance, a post hoc analysis revealed that no one characteristic predicted generalization across participants at 3 months posttreatment.

Conclusions

Response to phonomotor treatment does not appear to be influenced by aphasia and anomia severity level, error profile, participant age, or time postonset. Other factors, however, may influence response to intensive aphasia treatment and are worthy of continued exploration.
“Whatdunit?” Sentence Comprehension Abilities of Children With SLI: Sensitivity to Word Order in Canonical and Noncanonical Structures
Authors: Montgomery James W. , Gillam Ronald B. , Evans Julia L. , Sergeev Alexander V.
Published: August 2017

Purpose

With Aim 1, we compared the comprehension of and sensitivity to canonical and noncanonical word order structures in school-age children with specific language impairment (SLI) and same-age typically developing (TD) children. Aim 2 centered on the developmental improvement of sentence comprehension in the groups. With Aim 3, we compared the comprehension error patterns of the groups.

Method

Using a “Whatdunit” agent selection task, 117 children with SLI and 117 TD children (ages 7:0–11:11, years:months) propensity matched on age, gender, mother's education, and family income pointed to the picture that best represented the agent in semantically implausible canonical structures (subject–verb–object, subject relative) and noncanonical structures (passive, object relative).

Results

The SLI group performed worse than the TD group across sentence types. TD children demonstrated developmental improvement across each sentence type, but children with SLI showed improvement only for canonical sentences. Both groups chose the object noun as agent significantly more often than the noun appearing in a prepositional phrase.

Conclusions

In the absence of semantic–pragmatic cues, comprehension of canonical and noncanonical sentences by children with SLI is limited, with noncanonical sentence comprehension being disproportionately limited. The children's ability to make proper semantic role assignments to the noun arguments in sentences, especially noncanonical, is significantly hindered.
Modeling the Pathophysiology of Phonotraumatic Vocal Hyperfunction With a Triangular Glottal Model of the Vocal Folds
Authors: Galindo Gabriel E. , Peterson Sean D. , Erath Byron D. , Castro Christian , Hillman Robert E. , Zañartu Matías
Published: August 2017

Purpose

Our goal was to test prevailing assumptions about the underlying biomechanical and aeroacoustic mechanisms associated with phonotraumatic lesions of the vocal folds using a numerical lumped-element model of voice production.

Method

A numerical model with a triangular glottis, posterior glottal opening, and arytenoid posturing is proposed. Normal voice is altered by introducing various prephonatory configurations. Potential compensatory mechanisms (increased subglottal pressure, muscle activation, and supraglottal constriction) are adjusted to restore an acoustic target output through a control loop that mimics a simplified version of auditory feedback.

Results

The degree of incomplete glottal closure in both the membranous and posterior portions of the folds consistently leads to a reduction in sound pressure level, fundamental frequency, harmonic richness, and harmonics-to-noise ratio. The compensatory mechanisms lead to significantly increased vocal-fold collision forces, maximum flow-declination rate, and amplitude of unsteady flow, without significantly altering the acoustic output.

Conclusion

Modeling provided potentially important insights into the pathophysiology of phonotraumatic vocal hyperfunction by demonstrating that compensatory mechanisms can counteract deterioration in the voice acoustic signal due to incomplete glottal closure, but this also leads to high vocal-fold collision forces (reflected in aerodynamic measures), which significantly increases the risk of developing phonotrauma.
Short-Term Effect of Two Semi-Occluded Vocal Tract Training Programs on the Vocal Quality of Future Occupational Voice Users: “Resonant Voice Training Using Nasal Consonants” Versus “Straw Phonation”
Authors: Meerschman Iris , Van Lierde Kristiane , Peeters Karen , Meersman Eline , Claeys Sofie , D'haeseleer Evelien
Published: August 2017

Purpose

The purpose of this study was to determine the short-term effect of 2 semi-occluded vocal tract training programs, “resonant voice training using nasal consonants” versus “straw phonation,” on the vocal quality of vocally healthy future occupational voice users.

Method

A multigroup pretest–posttest randomized control group design was used. Thirty healthy speech-language pathology students with a mean age of 19 years (range: 17–22 years) were randomly assigned into a resonant voice training group (practicing resonant exercises across 6 weeks,
n
= 10), a straw phonation group (practicing straw phonation across 6 weeks,
n
= 10), or a control group (receiving no voice training,
n
= 10). A voice assessment protocol consisting of both subjective (questionnaire, participant's self-report, auditory–perceptual evaluation) and objective (maximum performance task, aerodynamic assessment, voice range profile, acoustic analysis, acoustic voice quality index, dysphonia severity index) measurements and determinations was used to evaluate the participants' voice pre- and posttraining. Groups were compared over time using linear mixed models and generalized linear mixed models. Within-group effects of time were determined using post hoc pairwise comparisons.

Results

No significant time × group interactions were found for any of the outcome measures, indicating no differences in evolution over time among the 3 groups. Within-group effects of time showed a significant improvement in dysphonia severity index in the resonant voice training group, and a significant improvement in the intensity range in the straw phonation group.

Conclusions

Results suggest that the semi-occluded vocal tract training programs using resonant voice training and straw phonation may have a positive impact on the vocal quality and vocal capacities of future occupational voice users. The resonant voice training caused an improved dysphonia severity index, and the straw phonation training caused an expansion of the intensity range in this population.
New method for indoor positioning by using wireless communication base stations
Authors: Zheng Xiaoyang , Su Hong , Wei Zhengyuan , Hu Shunren
Published: August 2017

A novel approach for indoor localisation is presented and it is composed of two mathematical models. One is a stochastic differential equation proposed to modify time of arrival of a mobile terminal (MT) to a base station (BS). Another is a multivariate optimisation model implemented to estimate the location of the MT by a random search algorithm. Through simulations using only the time of arrivals and measured coordinates of the BSs, the performance of the proposed scheme is evaluated by the measured coordinates of the 25 MTs. Simulation results demonstrate that the mean localisation error is only 0.5138 m and this method is very effective and applicable.
Robust output feedback fault‐tolerant control of non‐linear multi‐agent systems based on wavelet neural networks
Authors: Salimifard Maryam , Talebi Heidar Ali
Published: August 2017

A robust output feedback active fault‐tolerant leader‐following controller for a class of non‐linear multi‐agent systems is presented. It is assumed that the states of the followers are not available; therefore, a local observer is constructed to estimate the states of each agent. In addition, the non‐linear dynamics of agents may include uncertainties and the control input of the leader dynamics is unknown to all followers. Moreover, taking advantage of wavelet neural networks (WNNs), an online fault estimation scheme is developed which can effectively approximate the unknown actuator faults. The proposed decentralised observer‐based robust cooperative controller is capable of compensating for the effects of unknown time‐varying additive actuator faults, the model uncertainties, and the unknown input of the leader simultaneously. The stability analysis and convergence results that guarantee boundedness of all closed‐loop signals are investigated via Lyapunov's direct method. To demonstrate the effectiveness of the proposed approach, a network of single‐link manipulators is studied. As the results verify, the proposed WNN‐based fault estimation scheme can properly approximate the unknown actuator faults, which results in efficient compensation in the fault‐tolerant control design to achieve cooperative tracking objectives.
Adaptive tube‐based model predictive control for linear systems with parametric uncertainty
Authors: Jafari Fesharaki Sh. , Kamali M. , Sheikholeslam F.
Published: August 2017

A tube‐based robust model predictive control (MPC) is proposed to be applied in constrained linear systems with parametric uncertainty. An estimation method is applied in this proposed technique to adapt the system model at each sampling time and to reduce the conservatism nature of the tube‐based MPC as the system model approaches the real model as time passes. By updating the subject model online through this newly proposed approach the performance of the system is improved. Asymptotic stability of the closed‐loop system is established. The simulation results of a DC motor are applied to illustrate the effectiveness of this proposed controller in dealing with one practical system.
Multi‐objective optimisation of step voltage regulator operation and optimal placement for distribution systems design using linkage combination update‐non‐dominated sorting genetic algorithm‐II
Authors: Shigenobu Ryuto , Noorzad Ahmad Samim , Yona Atsushi , Senjyu Tomonobu
Published: August 2017

This study proposes the application of combinatorial multi‐objective optimisation (MOO) in an electrical power distribution system. Conventional electrical power systems do not consider reverse power flow, in which the power flows toward the feeder in the distribution system. However, reverse power flow toward the substation transformer is caused by voltage deviation with high penetration of distributed generators into a distribution system. Consequently, this causes faults in electric devices and may even lead to a massive blackout. To resolve voltage deviation problems, it is necessary to consider some trade‐offs. With this background, this study reveals three points. The first and second contributions regard general engineering research issues such as the definition of a new optimisation problem framework. To solve the problems discussed in this study, a new method of MOO was required. This method of MOO is applied to the power system to minimise voltage deviation while simultaneously minimising the number of required voltage control devices and operation. In addition, a new MOO method to determine the optimal placement of control devices while retaining operation diversity is proposed. Finally, each optimisation method is compared with numerical simulation and the advantages are summarised from the simulation results.
Bayesian information fusion for probabilistic health index of power transformer
Authors: Li Shuaibing , Ma Hui , Saha Tapan , Wu Guangning
Published: August 2017

This study proposes a Bayesian information fusion approach for determining the probabilistic health index of power transformer. The proposed approach integrates a variety of data obtained from transformer measurements, maintenance records, and failure statistics. By making use of these data, an inference model is constructed using Bayesian belief network (BBN). In the inference model, the significance of each individual measurement on the corresponding component in the BBN is decided by both principal component analysis and expert's experience, and subsequently quantified with a score‐probability transform. Finally, the inference model is used to derive a probabilistic health index. Case studies are provided to demonstrate the applicability of the proposed approach for evaluating transformer condition.
On the minimizing movement with the 1-Wasserstein distance
Authors: Agueh Martial , Carlier Guillaume , Igbida Noureddine
Published: August 2017

We consider a class of doubly nonlinear constrained evolution equations which may be viewed as a nonlinear extension of the growing sandpile model of [L. Prigozhin, Eur. J. Appl. Math.  7 (1996) 225–235.]. We prove existence of weak solutions for quite irregular sources by a semi-implicit scheme in the spirit of the seminal works of [R. Jordan et al., SIAM J. Math. Anal.  29 (1998) 1–17, D. Kinderlehrer and N.J. Walkington, Math. Model. Numer. Anal.  33 (1999) 837–852.] but with the 1-Wasserstein distance instead of the quadratic one. We also prove an L1-contraction result when the source is L1 and deduce uniqueness and stability in this case.
On the data completion problem and the inverse obstacle problem with partial Cauchy data for Laplace’s equation
Authors: Caubet Fabien , Dardé Jérémi , Godoy Matías
Published: August 2017

We study the inverse problem of obstacle detection for Laplace’s equation with partial Cauchy data. The strategy used is to reduce the inverse problem into the minimization of a cost-type functional: the Kohn–Vogelius functional. Since the boundary conditions are unknown on an inaccessible part of the boundary, the variables of the functional are the shape of the inclusion but also the Cauchy data on the inaccessible part. Hence we first focus on recovering these boundary conditions, i.e. on the data completion problem. Due to the ill-posedness of this problem, we regularize the functional through a Tikhonov regularization. Then we obtain several theoretical properties for this data completion problem, as convergence properties, in particular when data are corrupted by noise. Finally we propose an algorithm to solve the inverse obstacle problem with partial Cauchy data by minimizing the Kohn–Vogelius functional. Thus we obtain the gradient of the functional computing both the derivatives with respect to the missing data and to the shape. Several numerical experiences are shown to discuss the performance of the algorithm.
An Update on Direct C–H Bond Functionalization of Nitrogen-Containing Fused Heterocycles
Authors: Aziz Jessy , Piguel Sandrine
Published: August 2017

This report highlights the recent advances in direct C–H bond functionalization of 5,5- and 6,5-fused heterocycles containing at least two nitrogen atoms. Besides C–C bond formation, C–N, C–S, C–P, and C–Si bonds can also be created via a metal-catalyzed process. Some examples, where a C–H functionalization approach was applied for the synthesis of drug candidates, will be presented as well.

1 Introduction

2 C–H Functionalization Reactions of N-Containing Heterocycles

2.1 Imidazo[1,2-a]pyridines

2.2 Pyrrolo[1,2-a]pyrazines

2.3 Imidazo[1,2-b]pyrazoles

2.4 Imidazo[1,2-a]pyrimidines

2.5 Imidazo[1,2-a]pyrazines and Imidazo[1,5-a]pyrazines

2.6 Imidazo[1,2-b]pyridazines

2.7 Imidazo[4,5-b]pyridines and Imidazo[4,5-c]pyridines

2.8 Pyrazolo[3,4-b]pyridines

2.9 Pyrazolo[1,5-a]pyrimidines

2.10 Pyrrolo[2,3-d]pyrimidines and Pyrrolo[3,2-d]pyrimidines

2.11 Imidazo[1,2-b][1,2,4]triazines

2.12 Imidazo[1,2-b][1,2,4,5]tetrazines

3 Outlook

4 Conclusion
A Synthesis of Functionalized Thiazoles and Pyrimidine-4(3H)-thiones from 1,1,3,3-Tetramethylguanidine, Acetylenic Esters, and Aryl Isothiocyanates
Authors: Yavari Issa , Amirahmadi Asiyeh , Halvagar Mohammad
Published: August 2017

Aryl isothiocyanates react with dialkyl 2-{[bis(dimethylamino)methylene]amino}maleates, generated from 1,1,3,3-tetramethylguanidine and acetylenic esters, to afford 2-(dimethylamino)-1,3-thiazole derivatives, functionalized 2-(dimethylamino)-6-thioxo-1,6-dihydropyrimidines, and ethyl 2-(dimethylamino)-6-[(4-nitrophenyl)im­ino]-4-phenyl-6H-1,3-thiazine-5-carboxylate, in moderate to good yields.
Temporoparietal Fascia Free Flap for Nasoseptal Perforation Repair
Authors: Helman Samuel , Kadakia Sameep , Guthrie Ashley , Mourad Moustafa , Mashkevich Grigoriy
Published: August 2017

Nasoseptal perforations can be a challenging defect for the reconstructive surgeon, with repair limited by the surrounding tissue availability and the defect size. In patients with a history of cocaine use, often the integrity of surrounding vasculature is questionable and large defects may not be well suited for local reconstruction. In the otolaryngology literature, several reconstructive options using local tissue and synthetic materials have been described, but there have been no reports of microvascular free flaps utilized in this regard. We present a unique case of a 37-year-old woman with a 3.0 cm × 3.5 cm nasoseptal perforation secondary to cocaine use successfully reconstructed with a temporoparietal fascia free flap anastomosed to the facial artery and vein. Postoperatively, the patient had a well-healed septal defect from the free flap reconstruction This new technique shows promise as a feasible option for patients with large defects and for those with limited local reconstructive options. The ease of harvest and low donor-site morbidity make the temporoparietal fascia flap a suitable option for repair of complex nasoseptal defects.
Scrub Typhus with Varied Clinical Presentations
Authors: Banerjee Susrita , Roychowdhuri Satyabrata , Sarkar Mihir
Published: August 2017

We present four cases of pediatric scrub typhus from a tertiary care center of eastern India, emphasizing on varied unusual clinical manifestations posing diagnostic difficulties. A low index of suspicion is required to prevent under diagnosis. We report a case series of four patients with scrub typhus having uncommon clinical manifestations (two patients with hemophagocytic lymphohistiocytosis, one patient with myocarditis, and one patient presenting with shock reminiscent of dengue shock syndrome). The response to doxycycline was good, with fever subsiding within 48 to 72 hours of starting the treatment. Three out of four cases completely recovered once appropriate medication was given.
Neurotization of the Superficial Sensory Branch of Ulnar Nerve by the Distal Posterior Interosseous Nerve: Cadaveric Feasibility Study
Authors: Decaestecker Laurent , Delclaux Stépahnie , Apredoaei Costel , Tibbo Meagan , Courtade-Saïdi Monique , Mansat Pierre , Laumonerie Pierre
Published: August 2017

Background In 2014, Delclaux et al described a case wherein the Battiston and Lanzetta's technique, modified by utilization of the posterior interosseus nerve (PIN), was used to perform double neurotization of the ulnar nerve (UN). This study evaluates the feasibility of transfer of proprioceptive fascicles of the PIN to the superficial sensory branch of the UN (SSBUN).

Methods The surgeries were performed on 16 fresh cadaveric wrist specimens. PIN transfer was performed through the interosseous membrane and sutured to the SSBUN. The diameter for each nerve, number of fascicles, and the percentage of fascicles without axons, under ×10, ×40, and ×100 magnifications were performed by two observers.

Results Neurotization of the SSBUN by the PIN was successful in all cases. The median diameter of the SSBUN and PIN was 3.5 (3–4) and 2.3 mm (1.6–3), respectively. The SSBUN contained 5.5 fascicles (4–7), while the PIN contained 2 fascicles (0–4). The 16 PIN had limited (10 cases) or no axonal reserve (6 cases).

Conclusion This study supports the surgical and anatomical feasibility of neurotization of the SSBUN by the PIN. However, the PIN's limited axonal reserve may partially or totally compromise recovery.
Comparison of Imaging Softwares for Upper Airway Evaluation: Preliminary Study
Authors: dos Santos Trento Guilherme , Moura Lucas Borin , Spin-Neto Rubens , Jürgens Philipp Christian , Aparecida Cabrini Gabrielli Marisa , Pereira-Filho Valfrido Antônio
Published: August 2017

The interest about upper airway evaluation has increased lately. Therefore, many softwares have been developed aiming to improve and facilitate the analysis of airway volume. The objective of this study was to compare two different softwares packages, Mimics and Dolphin, in their accuracy and precision in upper airway space measurements. Preoperative cone beam computed tomography scans of nine nonsyndromic patients submitted to surgically assisted rapid maxillary expansion were included in this study. The imaging exams were converted to DICOM (digital imaging and communications in medicine) files and imported to the softwares. The mean volume for the Dolphin group (G1) was 10.791 cm3 (SD = 4.269 cm3) and for the Mimics group (G2) was 10.553 cm3 (SD = 4.564 cm3). There was no statistically significant difference between the two groups ( p = 0.105).
Glossopharyngeal Nerve Block: The Premolar Approach
Authors: Rao Sruthi , Rao Santhosh
Published: August 2017

This is a technical note describing hard tissue landmarks to simplify the intraoral glossopharyngeal nerve block. Our literature review revealed no specific mention of the same procedure in documented data.
Analysis of the Changing Patterns of Midface Fractures Using 3D Computed Tomography: An Observational Study
Authors: Satish Preeti , Prasad Kavitha , Lalitha R. M. , Ranganath Krishnappa , Sagar Parimala
Published: August 2017

This article aims to analyze the changing Le Fort fracture patterns using computed tomography (CT) scans with three-dimensional (3D) reconstruction. A prospective observational study was conducted on 60 patients with midface trauma, who had reported to MS Ramaiah Group of Hospitals, Bangalore, between January 2015 and October 2016. CT scans using 1.6 mm axial, sagittal, coronal sections were taken and their 3D reconstruction was made. The images were studied and compared with the standard Le Fort lines. The deviations from the classical Le Fort lines were analyzed and recorded. A note was also made of any additional fixation that was required for these deviations. Descriptive analysis was done and the results expressed in numbers and percentages. Study revealed that the most common cause for the midface fractures was found to be road traffic accidents (81.7%) with a male preponderance (88.3%) and peak incidence in 21 to 30 years of age (40%). Among the 60 patients, 18 (30%) patients had fracture patterns similar to the ideal Le Fort lines, 4 (6.6%) had a combination of Le Fort patterns, and 38 (66.3%) patients had deviations seen from the ideal Le Fort lines. Four types of deviations were recorded, namely, D1(60%), D2(5.4%), D3(10.9%), and D4(23.6%). It was observed that D1 and D3 required additional fixation. Majority of the cases presented as a deviation from ideal Le Fort fractures. CT was a valuable tool in the assessment of these fracture patterns. Deviations, if any, could be better analyzed using the 3D reconstruction images. Proper diagnosis and detection of these deviations make the planning for fixation easier. Repetition of these deviations could propose a newer or modified classification system for Le Fort fractures.
The Propeller Concept Applied to Free Flaps and the Proposal of a “Clock Flap” Nomenclature
Authors: Rossello Carlo , Salomone Carlo , Carrega Giuliana , Felli Lamberto , Burastero Giorgio , Antonini Andrea
Published: August 2017

Background It is a common experience for reconstructive surgeons to feel the necessity for large flaps and minimal donor-site morbidity at the same time. In the reported cases where we felt this call intraoperatively, we have met our need by applying the “propeller concept” to fasciocutaneous or composite flaps, separating and rotating its different tissue components.

Methods We present a series of five cases in which we separated and rotated diversely fascial and cutaneous components of free perforator flaps to enhance the extension of the flap or to tailor it better on the tissue gap for optimal functional and aesthetic results. We also propose a simple nomenclature system for rotation angles' definition, summarized as the “clock flap” classification, where the different components of the flap represent the arms of a clock which has the main vessel axis on the 12–6 line.

Results All reconstructive procedures succeeded with only minor complications. No partial failure due to vessel rotations was noticed.

Conclusion Applying “propeller style” rotations to different components of free flaps seems to be a safe procedure which may help maximize flap performance in terms of coverage of the recipient site, while minimizing scars and impairment of the donor site. Also, the proposed nomenclature gives the opportunity to record and compare surgical procedures for statistical analysis.
Computertomografie oder Magnetresonanztomografie? – Welche „Röhre“ ist wann die
Richtige?
Authors: Fromme Vivian , Köhler Claudia , Moritz Anne-Kristin , Piesnack Susann , Alef Michaele , Kiefer Ingmar
Published: August 2017

Die Bandbreite der diagnostischen Möglichkeiten nimmt zu und immer häufiger steht der überweisende
Praktiker vor der Frage: CT oder MRT – welches Verfahren ist für diesen Patienten und die Diagnosefindung
geeigneter? Im Folgenden erläutern die Autoren exemplarisch, anhand ausgewählter Beispiele, wann welches
Schnittbildverfahren empfohlen wird.
Mammatumoren beim Hund – Teil 1: Ein Überblick über Risikofaktoren und die histologische
Klassifikation
Authors: Krastel Dorothee
Published: August 2017

Mammatumore gehören zu den häufigsten Tumorerkrankungen der Hündin. Der 1. Teil des Beitrags gibt einen
Überblick über mögliche Risikofaktoren und die Histologie des Tumors. In diesem Zusammenhang werden unter
anderem der Einfluss der Frühkastration auf das Risiko der Entstehung von Mammatumoren und anderen
Tumoren bei der Hündin diskutiert.
Antiemetische Therapie bei Hund und Katze – Welche Therapie eignet sich bei
welcher Kausalität?
Authors: Ryba Kristina , Heilmann Romy
Published: August 2017

Patienten mit Erbrechen werden täglich in der tierärztlichen Praxis vorgestellt. So
unterschiedlich die Ursachen für diesen Schutzreflex sein können, so genau sollte der
Kleintierpraktiker seine Therapie für den bestmöglichen Behandlungserfolg hierauf
abstimmen. Dieser Artikel gibt einen Überblick über die häufigsten in der Kleintierpraxis
eingesetzten Antiemetika, deren Einsatzgebiete, Wirkungen und Dosierungen.
Entwicklungsaufgaben, psychische Gesundheit und Risiken von jungen Erwachsenen mit Typ-1-Diabetes
Authors: Rölver Klaus-Martin , Lange Karin
Published: August 2017

Junge Erwachsene mit Typ-1-Diabetes sind mit vielen alters- und gesundheitsspezifischen Herausforderungen konfrontiert. Für viele gut geschulte und durch Fachteams in Schwerpunktpraxen begleitete Patienten bedeutet das Diabetesmanagement heute jedoch keine außergewöhnlich große Belastung mehr. Einige junge Erwachsene sind allerdings überfordert, wenn sie alterstypische Entwicklungsaufgaben mit der eigenverantwortlichen Therapie ihres Diabetes vereinbaren sollen. Oft betrifft dies gerade diejenigen, die bereits in ihrer Kindheit und im Jugendalter eine unzureichende Stoffwechseleinstellung und gehäuft akute Komplikationen erlebt haben. Die Komorbidität einer psychischen Belastung oder psychiatrischen Störung beeinträchtigt das erfolgreiche Diabetesmanagement in diesem Lebensabschnitt erheblich. Zudem können altersspezifische Krisen und belastende Lebensereignisse einer sachgerechten Diabetestherapie entgegenstehen. Solchen typischen Risiken gilt es erfolgreich zu begegnen.
Psychotherapie: Quo vadis?
Authors: Meinlschmidt Gunther , Tegethoff Marion
Published: August 2017

Hintergrund: Psychotherapie hat den Anspruch, sich kontinuierlich weiter
zu entwickeln. Ziel dieser Arbeit ist es ausgewählte neue Impulse im Forschungs-
und Praxisfeld Psychotherapie zu beschreiben.

Methoden: Der vorliegende Artikel synthetisiert und kondensiert, als
selektives narratives Review, ausgewählte relevante Literatur verschiedener
Datenbanken, einschließlich MEDLINE, EMBASE, PsycINFO und „Web of Science“ sowie
zitierender und zitierter Arbeiten, um bedeutsame Entwicklungsstränge im Bereich
Psychotherapie herauszuarbeiten.

Ergebnisse: Folgende Entwicklungsstränge werden beschrieben: 1) In
Anknüpfung an die sogenannte dritte Welle der Verhaltenstherapie entstehen neue
Interventionen, die insbesondere die Förderung (zwischen)menschlicher Tugenden,
wie Mitgefühl, Vergebung und Dankbarkeit zum Kern haben; 2) Basierend auf
technologischen Quantensprüngen entstehen neue Interventionen, die sich unter
anderem Fortschritte im Bereich neuer Medien, Informations-, und
Kommunikationstechnologien sowie neuronaler Bildgebung zunutze machen, wie zum
Beispiel digitale Interventionen bei psychischen Störungen und neue Formen von
Neurofeedback; 3) Inspiriert durch den Bereich Positive Psychologie erfährt die
Förderung von Stärken und Resilienz im therapeutischen Kontext eine Renaissance;
4) Einhergehend mit dem neuen Paradigma einer „Präzisionsmedizin“ wird die Frage
der differentiellen und adaptiven Indikation von Psychotherapie gänzlich neu
gestellt und mittels neuer Methoden in Richtung einer „Präzisionspsychotherapie“
vorangetrieben; 5) Schließlich eröffnet der „embodied turn“ die Möglichkeit,
dass Körperpsychotherapie in der akademisch geprägten Psychotherapielandschaft
an Bedeutung gewinnt.

Schlussfolgerung: Diese und weitere Entwicklungen, wie die Arbeit mit
systemischen Netzwerkmodellen oder die Nutzung maschinellen Lernens,
illustrieren die lebendigen Aktivitäten im Bereich Psychotherapie.
Die Kraftwerke der Zellen- über die Behandlung von
psychiatrischen Symptomen bei Patienten mit Mitochondriopathien
Authors: Mörkl Sabrina , Tmava Adelina , Blesl Claudia , Schmiedhofer Franziska , Wurm Walter E. , Holl Anna , Painold Annamaria
Published: August 2017

Einleitung Mitochondriopathien sind Erkrankungen der Zellorganellen,
welche für die Herstellung des Energieträgers Adenosin-Tri-Phosphat (ATP)
essentiell sind. Bei Mutationen entsteht eine mannigfaltige Symptomatik
besonders jener Organe, welche auf eine stetige Energieversorgung angewiesen
sind- wie zum Beispiel das Nervensystem. Obwohl psychiatrische Symptome bei
Mitochondriopathien häufig sind, finden diese im klinischen Alltag kaum
Beachtung.

Kasuistik Wir berichten über eine 21-jährige Patientin, welche aufgrund
von Panikattacken und Depressionen unsere Akutambulanz aufsuchte. Die Patientin
entwickelte im Vorfeld ausgeprägte Nebenwirkungen auf eine niedrigdosierte
Sertralin-Therapie.

Schlussfolgerung Mitochondriopathien sind selten, bedürfen jedoch
unbedingt einer Anpassung der psychopharmakologischen Therapie. Viele
Psychopharmaka können die Atmungskette beeinträchtigen und so zur Entstehung von
ausgeprägten Nebenwirkungen führen.
Highlights vom ADA 2017
Authors: Schikora Stephanie
Published: August 2017

Auch 2017 waren kardiovaskuläre Sicherheits- und Endpunktstudien wesentliche Highlights des Kongresses der „American Diabetes Association“ (ADA) – im Fokus standen dabei unter anderem DEVOTE, CANVAS, LEADER, REMOVAL und ODYSSEY Diabetes. Denn will man die Prognose von Menschen mit Typ-2-Diabetes positiv beeinflussen, gilt es neben der Kontrolle der Blutzuckerwerte insbesondere, das kardiovaskuläre Risiko der Patienten zu senken.
Picosecond cubic and quintic nonlinearity of lithium niobate at 532 nm
Authors: Wang Hongzhen , Boudebs Georges , de Araújo Cid B.
Published: August 2017

The nonlinear (NL) optical response of bulk lithium niobate (LiNbO3) was investigated at 532 nm using the second harmonic of a Nd:YAG laser delivering pulses of 12 ps. The experiments were performed using the D4σ method combined with the conventional Z-scan technique. Two- and three-photon absorption coefficients equal to 0.27 cm/GW and 2.5×10−26 m3/W2, respectively, were determined. The NL absorption processes were due to transitions from the valence to the conduction band and to free-carrier absorption. The third- and fifth-order NL refractive indices were n2=(2.5±0.6)×10−19 m2/W and n4<5.5×10−36 m4/W2. The present results give the support for previous experiments that indicate possible fifth-order processes in bulk samples and channel waveguides fabricated with LiNbO3.
Craters and nanostructures on BaF2 sample induced by a focused 46.9nm laser
Authors: Cui Huaiyu , Zhang Shuqing , Li Jingjun , Lu Haiqiang , Zhao Yongpeng
Published: August 2017

We successfully damaged BaF2 samples by a 46.9nm capillary discharge laser of 100μJ focused by a toroidal mirror at a grazing incidence. Ablation craters with clear boundaries were detected by optical microscope and atomic force microscope (AFM). Laser-induced nanostructures with a period of ∼1μm were observed in the ablation area under single pulse irradiation and multiple pulses irradiation. The surface behavior was compared and analyzed with that induced by the laser of 50μJ. The nanostructures were supposed to be attributed to the thermoelastic effect and the period of the structures was effected by the energy of the laser.
Room temperature transparent conducting magnetic oxide (TCMO) properties in heavy ion doped oxide semiconductor
Authors: Lee Juwon , Nagarajan Ganapathi Subramaniam , Shon Yoon , Kwon Younghae , Kang Tae Won , Kim Deuk Yong , Kim Hyungsang , Im Hyunsik , Park Chang-Soo , Kim Eun Kyu
Published: August 2017

Bismuth doped ZnO (ZnBi0.03O0.97) thin films are grown using pulsed laser deposition. The existence of positively charged Bi, absence of metallic zinc and the Zn-O bond formation in Bi doped ZnO are confirmed using X-ray Photoelectron Spectroscopy (XPS). Temperature dependent resistivity and UV-visible absorption spectra show lowest resistivity with 8.44 × 10-4 Ω cm at 300 K and average transmittance of 93 % in the visible region respectively. The robust ferromagnetic signature is observed at 350 K (7.156 × 10-4 emu/g). This study suggests that Bi doped ZnO films should be a potential candidate for spin based optoelectronic applications.
Single-frequency reflection characterisation of shock tube excited plasma
Authors: Tian Jing , Tang Pu , Ma Ping , Li Lutong , Li Ruiming , He Ziyuan , Chen Bo
Published: August 2017

Plasma has been of great interest to engineers and scientists during the past few decades due to its wide applications. Besides, the plasma-sheath-caused lose of communication (i.e. re-entry blackout) that happens when a spacecraft re-enters the earth atmosphere is still a problem to be solved. The microwave characterisation of shock tube excited plasma has been an important method for exploring the transmission and reflection of microwave signals in plasma. The existing frequency sweep or multi-frequency technologies are not desirable for the characterisation of high-speed time-varying plasma generated in shock tubes. Hence, in this paper a novel signal-frequency approach is proposed to measure both electron density and collision frequency of plasma in shock tube. As frequency sweep is not required in this method, it is extremely suitable for characterising the shock tube excited high-speed time-varying plasma. The genetic algorithm is applied to extract electron density and collision frequency from the reflection coefficient. Simulation results demonstrate excellent accuracy for electron density within 1010∼1012 cm−3 and collision frequency within 5×1010∼1012 Hz. This work paves the way for a fast and compact microwave reflection measurement of shock tube generated plasma.
The ionic states of difluoromethane: A reappraisal of the low energy photoelectron spectrum including ab initio configuration interaction computations
Authors: Palmer Michael H. , Biczysko Malgorzata , Baiardi Alberto , Coreno Marcello , de Simone Monica , Grazioli Cesare , Hoffmann Søren Vrønning , Jones Nykola C. , Peterson Kirk A.
Published: August 2017

A new synchrotron-based study of the photoelectron spectrum (PES) of difluoromethane is interpreted by an ab initio analysis of the ionic states, which includes Franck-Condon (FC) factors. Double differentiation of the spectrum leads to significant spectral sharpening; the vibrational structure observed is now measured with greater accuracy than in previous studies. Several electronic structure methods are used, including equation of motion coupled cluster calculations with single and double excitations (EOM-CCSD), its ionization potential variant EOM-IP-CCSD, 4th order Møller-Plesset perturbation theory (MP4SDQ) configuration interaction (CI), and complete active space self-consistent-field (CASSCF) methods. The adiabatic ionization energies (AIEs) confirm the assignments as band I, one state 12B1 (12.671 eV); band II, three states, 12B2 (14.259) < 12A1 (15.030) < 12A2 (15.478 eV); and band III, three states, 22B2 (18.055) < 22A1 (18.257) < 22B1 (18.808 eV). The three ionizations in each of the bands II and III lead to selective line broadening of the PES structure, which is attributed to vibronic overlap. The apparent lack of a vibrational structure attributable to both the 12A1 and 22A1 states in the PES arises from line broadening with the preceding states 12B2 and 22B2, respectively. Although these 2A1 states clearly overlap with their adjacent higher IE, some vibrational structure is observed on the higher IE. The effects of vibronic coupling are evident since the observed structure does not fit closely with the calculated Born-Oppenheimer FC profiles. Correlation of the lowest group of four AIEs in the PES of other members of the CH2X2 group, where X = F, Cl, Br, and I, clearly indicate these effects are more general.
A method for measuring the spin polarization of 129Xe by using an atomic magnetometer
Authors: Chen Linlin , Zhou Binquan , Lei Guanqun , Wu Wenfeng , Zhai Yueyang , Wang Zhuo , Fang Jiancheng
Published: August 2017

We propose a method for the precise determination of nuclear spin polarization, based on the atomic magnetometers, which employs the effective magnetic field produced by the spin polarization of 129Xe nuclei. This effective magnetic field can be estimated by measuring the initial induced voltage of the Free Induction Decay (FID) signal of the 129Xe nuclei, which is based on the calibration coefficient between the transverse magnetic field and the output voltage signal of the atomic magnetometer, by using an off-resonant transverse driven magnetic field. Compared with the method based on measuring the longitudinal relaxation time of the 129Xe nuclei and the spin polarization of alkali-metal atoms, our method can directly measure the nuclear spin polarization, without being affected by inaccuracies in the measurement of the spin polarization of alkali-metal atoms.