bluuebunny/crossref_metadata_2025 huggingface dataset:
EFEKTIFITAS PIJAT BAYI TERHADAP KUALITAS TIDUR PADA BAYI USIA 3-12 BULAN
Authors: Wardani Jihan Virgia , Choirunissa Risza , Kundaryanti Rini
Published: May 2023

Latar Belakang: Kualitas tidur yang baik sangat penting bagi pertumbuhan bayi, karena aktivitas tidur merupakan salah satu stimulus bagi proses tumbuh kembang otak, saat anak tidur otak mengeluarkan 75% hormon pertumbuhan  yang bertugas merangsang pertumbuhan dan jaringan. Pijat bayi adalah memberikan rangsangan taktil pada kulit bayi yang dapat meningkatan sekresi hormon serotonin yang akan menghasilkan melatonin yang berperan dalam tidur dan membuat tidur lebih lama dan lelap pada malam hari. Tujuan: Penelitian ini untuk mengetahui efektifias pijat bayi terhadap kualitas tidur pada bayi usia 3-12 bulan di Klinik wilayah kota Bogor Tahun 2022. Metodologi: Penelitian ini menggunakan Quasy-experiment dengan Pretest-posttest with control group desain. Populasi pada penelitian ini adalah bayi usia 3-12 bulan. Pengambilan sampel dilakukan menggunakan teknik proporsive sampling yang berjumlah 30 bayi yang terdiri dari 15 orang kelompok intervensi dan 15 kelompok kontrol. Instrument dalam penelitian ini berupa lembar kuesioner. Analisis data menggunakan uji wilcoxon test untuk mengetahui perbedaan rata-rata dalam kelompok dan uji mann withney untuk mengetahui perbandingan antar kelompok. Hasil: Didapatkan hasil bahwa terdapat perbedaan rata-rata intensitas kualitas tidur pada bayi usia 3-12 bulan seblum dan sesudah diberikan intervensi pijat bayi dengan hasil uji Wilcoxon test p value 0,001 (p<0,05). Diskusi: Ada pengaruh pemberian intervensi pijat bayi terhadap kualitas tidur pada bayi usia 3-12 bulan di Klinik wilayah kota Bogor tahun 2022. Dengan adanya penelitian ini diharapkan pijat bayi dapat menjadi pilihan obat nonfarmakologi dalam meningkatkan kualitas tidur pada bayi usia 3-12 bulan.
EFEKTIVITAS PEMBERIAN MINUMAN JAHE DAN AROMATERAPI PEPPERMINT TERHADAP EMESIS GRAVIDARUM PADA IBU HAMIL TRIMESTER I
Authors: Kholifa Rosary Diana , Choirunissa Risza , Kundaryanti Rini
Published: May 2023

Latar belakang: Pada awal kehamilan, mual dan muntah merupakan gejala yang sering terjadi dan menyebabkan ketidaknyamanan pada ibu hamil. Setiap ibu hamil akan merasakan intensitas mual dan muntah yang berbeda-beda dan dapat diatasi dengan metode farmakologis dan non farmakologis. Tujuan: Untuk mengetahui pengaruh pemberian minuman jahe (Zingiber officinale) dan aromaterapi peppermint (Mentha x piperita) terhadap emesis gravidarum pada ibu hamil trimester I di PMB N, Tangerang Selatan. Metodologi: Penelitian ini menggunakan desain quasi eksperimental pretest-posttest dengan kelompok kontrol. Pengambilan sampel dilakukan dengan menggunakan teknik purposive sampling, sebanyak 30 ibu hamil trimester pertama (0-12 minggu), yang terdiri dari 15 kelompok intervensi dan 15 kelompok kontrol. Instrumen dalam penelitian ini adalah lembar pengukuran dengan menggunakan sistem penilaian (PUQE) -24, lembar observasi, informed consent, minuman jahe (Zingiber officinale) dan aromaterapi peppermint (Mentha x piperita). Untuk menentukan apakah ada perbedaan skor sebelum dan sesudah intervensi, statistik deskriptif dan uji-t berpasangan digunakan dalam analisis data. Perbedaan antara kelompok kemudian diperiksa menggunakan uji-t independen. Hasil: Penelitian menunjukkan bahwa terdapat perbedaan rata-rata intensitas mual dan muntah sebelum dan sesudah diberikan minuman jahe (Zingiber iffocinale) dan aromaterapi peppermint (Mentha x piperita). Hasil uji t berpasangan didapatkan nilai p-value 0,00 (p<0,05) dan uji independen didapatkan nilai p-value 0,01 (p<0,05). Kesimpulan dan Saran: Minuman jahe dan Aromaterapi peppermint menjadi salah satu alternatif obat nonfarmakologi untuk mengurangi gejala mual muntah dalam kehamilan.
The first detection of DNA of Caryophyllaeus laticeps (Pallas, 1781) in sunbleak Leucaspius delineatus (Heckel, 1843)
Authors: Denikina N.N. ,   Limnological Institute of the Siberian Branch of the Russian Academy of Sciences, 3 Ulan-Batorskaya Str., Irkutsk, 664033, Russia, Kulakova N.V. ,   Siberian Institute of Plant Physiology and Biochemistry of the Siberian Branch of the Russian Academy of Sciences, 132 Lermontova Str., Irkutsk, 664033, Russia, Bukin Y.S. ,   Limnological Institute of the Siberian Branch of the Russian Academy of Sciences, 3 Ulan-Batorskaya Str., Irkutsk, 664033, Russia, Khamnueva T.R. ,   Institute of General and Experimental Biology of the Siberian Branch of the Russian Academy of Sciences, 6 Sakhyanovoi Str., Ulan-Ude, 670047, Russia, Baldanova D.R. ,   Institute of General and Experimental Biology of the Siberian Branch of the Russian Academy of Sciences, 6 Sakhyanovoi Str., Ulan-Ude, 670047, Russia, Bogdanov B.E. ,   Limnological Institute of the Siberian Branch of the Russian Academy of Sciences, 3 Ulan-Batorskaya Str., Irkutsk, 664033, Russia, Dzyuba E.V. ,   Limnological Institute of the Siberian Branch of the Russian Academy of Sciences, 3 Ulan-Batorskaya Str., Irkutsk, 664033, Russia
Published: May 2023

Abstract. DNA of Caryophyllaeus laticeps (Pallas, 1781) (Cestoda: Caryophyllidea) was first found in the intestine of common sunbleak Leucaspius delineatus (Heckel, 1843) from the Irkutsk Reservoir. The aim of the study was to carry out a comparative analysis and reconstruction of the phylogenetic position of the parasite. Determination of the cox1 gene fragment and comparative analysis of the obtained and available in genetic databases nucleotide sequences showed high nucleotide diversity of C. laticeps both in the studied samples (0 6.4%) and in the reference sequences from the GenBank database (0 6.8%). The sequences of C. laticeps in the phylogenetic tree formed three clades containing local samples of sunbleak parasites in all of them. The most represented genotype (75%) is clustered with parasite sequences of the bream Abramis brama (Linnaeus, 1758) from Switzerland, Slovakia, and the European part of Russia. Another significant genotype (19%) is in the joint cluster with the C. laticeps sequences of the common carp Cyprinus carpio Linnaeus, 1758 (Italy). The need for additional studies on the biology and ecology of C. laticeps and revision of caryophyllid cestodes in fish in the Angara River and Lake Baikal were under consideration.
Partizipative Klimapolitik: Wie die Integration von Stakeholder- und Bürger*innenbeteiligung gelingen kann (online first)
Authors: Oppold Daniel , Renn Ortwin
Published: May 2023

Politisch Verantwortliche, die vor gesamtgesellschaftlichen Herausforderungen wie der Entwicklung einer wirksamen Klimapolitik stehen, sind aufgrund der Komplexität und Tragweite der Materie mehr denn je auf die Beteiligung von Stakeholdern und Bürger*innen angewiesen. Dies gilt insbesondere für die kommunale Ebene. In diesem Beitrag zeigen wir auf, welche Potenziale in der prozeduralen Integration von Stakeholder- und Bürger*innenbeteiligung liegen und wie diese Kombination in der Praxis gelingen kann. Dazu bereiten wir zunächst die theoretischen und praktischen Kernmerkmale der verbreiteten Beteiligungsinstrumente Bürger*innenrat und Runder Tisch auf. Anschließend analysieren wir zwei empirische Fallstudien, in denen jeweils sowohl eine Stakeholdergruppe als auch eine nach dem Zufallsprinzip geloste Bürger*innengruppe im Rahmen eines Gesamtprozesses gemeinsam Empfehlungen für klimapolitische Maßnahmenkataloge erarbeitet haben. Unsere Analyse zeigt, dass integrierte Gesamtbeteiligungsprozesse bei einer sorgfältigen Strukturierung der Interaktionen zwischen Stakeholdern und zufällig ausgewählten Bürger*innen sowie einem toleranten Umgang mit auftretenden Dissensen sachlich fundierte und politisch wirksame Ergebnisse erzielen können.
Multifocal Transcranial Direct Current Stimulation in Primary Progressive Aphasia Does Not Provide a Clinical Benefit Over Speech Therapy
Authors: Borrego-Écija Sergi , Montagut Nuria , Martín-Trias Pablo , Vaqué-Alcázar Lídia , Illán-Gala Ignacio , Balasa Mircea , Lladó Albert , Casanova-Mollà Jordi , Bargalló Nuria , Valls-Solé Josep , Lleó Alberto , Bartrés-Faz David , Sánchez-Valle Raquel
Published: May 2023

Background: Primary progressive aphasia (PPA) is a group of neurodegenerative disorders including Alzheimer’s disease and frontotemporal dementia characterized by language deterioration. Transcranial direct current stimulation (tDCS) is a non-invasive intervention for brain dysfunction. Objective: To evaluate the tolerability and efficacy of tDCS combined with speech therapy in the three variants of PPA. We evaluate changes in fMRI activity in a subset of patients. Methods: Double-blinded, randomized, cross-over, and sham-controlled tDCS study. 15 patients with PPA were included. Each patient underwent two interventions: a) speech therapy + active tDCS and b) speech therapy + sham tDCS stimulation. A multifocal strategy with anodes placed in the left frontal and parietal regions was used to stimulate the entire language network. Efficacy was evaluated by comparing the results of two independent sets of neuropsychological assessments administered at baseline, immediately after the intervention, and at 1 month and 3 months after the intervention. In a subsample, fMRI scanning was performed before and after each intervention. Results: The interventions were well tolerated. Participants in both arms showed clinical improvement, but no differences were found between active and sham tDCS interventions in any of the evaluations. There were trends toward better outcomes in the active tDCS group for semantic association and reading skills. fMRI identified an activity increase in the right frontal medial cortex and the bilateral paracingulate gyrus after the active tDCS intervention. Conclusion: We did not find differences between active and sham tDCS stimulation in clinical scores of language function in PPA patients.
TODIM-VIKOR method for performance evaluation of school-enterprise cooperation in vocational colleges under 2-tuple linguistic Pythagorean fuzzy sets
Authors: Han Yongguang , Xu Xinrui
Published: May 2023

As an important way to cultivate talents, school-enterprise cooperation is highly praised by the educational and economic circles of all countries. Vocational education spans enterprises and schools, and is an education of cross-border innovation. Vocational schools should make the people they cultivate meet the needs of the market and enterprises, and carry out in-depth school-enterprise cooperation is one of the effective ways. The school-enterprise cooperation between vocational colleges and enterprises makes vocational education more targeted and practical, and plays an important role in the training of skilled talents. It is not only an inevitable requirement for enterprise development and participation in competition, but also an important direction of China’s vocational education reform, and is the fundamental outlet for the development of China’s vocational education. The performance evaluation of school-enterprise cooperation in vocational colleges is classical multiple-attribute group decision-making (MAGDM) issues. Recently, the TODIM and VIKOR method has been used to solve MAGDM issues. The 2-tuple linguistic Pythagorean fuzzy sets (2TLPFSs) are used as a tool for characterizing uncertain information during the performance evaluation of school-enterprise cooperation in vocational colleges. In this manuscript, we design the 2-tuple linguistic Pythagorean fuzzy TODIM-VIKOR(2TLPF-TODIM-VIKOR) method to solve the MAGDM under 2TLPFSs. In the end, a numerical case study for performance evaluation of school-enterprise cooperation in vocational colleges is given to validate the proposed method.
RNA Transcript Diversity in Neuromuscular Research
Authors: Lim Wooi Fang , Rinaldi Carlo
Published: May 2023

Three decades since the Human Genome Project began, scientists have now identified more then 25,000 protein coding genes in the human genome. The vast majority of the protein coding genes (> 90%) are multi-exonic, with the coding DNA being interrupted by intronic sequences, which are removed from the pre-mRNA transcripts before being translated into proteins, a process called splicing maturation. Variations in this process, i.e. by exon skipping, intron retention, alternative 5’ splice site (5’ss), 3’ splice site (3’ss), or polyadenylation usage, lead to remarkable transcriptome and proteome diversity in human tissues. Given its critical biological importance, alternative splicing is tightly regulated in a tissue- and developmental stage-specific manner. The central nervous system and skeletal muscle are amongst the tissues with the highest number of differentially expressed alternative exons, revealing a remarkable degree of transcriptome complexity. It is therefore not surprising that splicing mis-regulation is causally associated with a myriad of neuromuscular diseases, including but not limited to amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), Duchenne muscular dystrophy (DMD), and myotonic dystrophy type 1 and 2 (DM1, DM2). A gene’s transcript diversity has since become an integral and an important consideration for drug design, development and therapy. In this review, we will discuss transcript diversity in the context of neuromuscular diseases and current approaches to address splicing mis-regulation.
Eye Muscle MRI in Myasthenia Gravis and Other Neuromuscular Disorders
Authors: Keene Kevin R. , Notting Irene C. , Verschuuren Jan J.G.M. , Voermans N. , de Keizer Ronald. O.B. , Beenakker Jan-Willem M. , Tannemaat Martijn R. , Kan Hermien E.
Published: May 2023

Introduction: MRI of extra-ocular muscles (EOM) in patients with myasthenia gravis (MG) could aid in diagnosis and provide insights in therapy-resistant ophthalmoplegia. We used quantitative MRI to study the EOM in MG, healthy and disease controls, including Graves’ ophthalmopathy (GO), oculopharyngeal muscular dystrophy (OPMD) and chronic progressive external ophthalmoplegia (CPEO). Methods: Twenty recently diagnosed MG (59±19yrs), nineteen chronic MG (51±16yrs), fourteen seronegative MG (57±9yrs) and sixteen healthy controls (54±13yrs) were included. Six CPEO (49±14yrs), OPMD (62±10yrs) and GO patients (44±12yrs) served as disease controls. We quantified muscle fat fraction (FF), T2water and volume. Eye ductions and gaze deviations were assessed by synoptophore and Hess-charting. Results: Chronic, but not recent onset, MG patients showed volume increases (e.g. superior rectus and levator palpebrae [SR+LPS] 985±155 mm3 compared to 884±269 mm3 for healthy controls, p < 0.05). As expected, in CPEO volume was decreased (e.g. SR+LPS 602±193 mm3, p < 0.0001), and in GO volume was increased (e.g. SR+LPS 1419±457 mm3, p < 0.0001). FF was increased in chronic MG (e.g. medial rectus increased 0.017, p < 0.05). In CPEO and OPMD the FF was more severely increased. The severity of ophthalmoplegia did not correlate with EOM volume in MG, but did in CPEO and OPMD. No differences in T2water were found. Interpretation: We observed small increases in EOM volume and FF in chronic MG compared to healthy controls. Surprisingly, we found no atrophy in MG, even in patients with long-term ophthalmoplegia. This implies that even long-term ophthalmoplegia in MG does not lead to secondary structural myopathic changes precluding functional recovery.
Drugs to the Rescue: Comparison of On-Demand Therapies for OFF Symptoms in Parkinson’s Disease
Authors: Martinez-Nunez Alfonso E. , LeWitt Peter A.
Published: May 2023

Patients with Parkinson’s disease often suffer from OFF symptoms disrupting their daily routines and adding to disabilities. Despite polypharmacy and adjustments to medication schedules, they often do not experience consistent relief from their motor symptoms. As the disease progresses, impaired gastric emptying may evolve, making it even more challenging for dopaminergic drugs to provide consistent results. This review focuses on a group of drugs that have the pharmacokinetic advantage of a much earlier onset of action by virtue of their non-oral routes of absorption. We compare the current marketed options: subcutaneous apomorphine, sublingual apomorphine, and inhaled levodopa. Subcutaneous apomorphine is the speediest to take effect, whereas sublingual apomorphine offers the longest clinical effect. Inhaled levodopa has the most favorable side effect profile among the three options. An inhaled form of apomorphine is currently under development, having passed safety and efficacy studies. Each of these drugs has unique characteristics for the user, including different side effect profiles and onset of action. The best choice for a patient will depend on individual needs and circumstances. In this review, we explore those nuances to allow clinicians to select the best option for their patients.
A newborn with ectrodactyly, tetralogy of Fallot, esophageal atresia, hypospadias and TP63 gene mutation: A new type of EEC Syndrome?
Authors: Sodero G. , Colonna A. Turriziani , Purcaro V. , Onesimo R. , Zampino G. , Vento G.
Published: May 2023

EEC syndrome is an autosomal dominant genetic disease with incomplete penetrance characterized by ectrodactyly, ectodermal dysplasia, and cleft lip/palate; these manifestations can differently occur in the affected subjects and can also be associated with other anomalies, such as in the urogenital tract. We reported the case of a newborn with prenatal diagnosis of EEC type 3 associated with severe cardiac abnormalities (Tetralogy of Fallot), high esophageal atresia with fistula and penoscrotal hypospadias.
Predicting mHealth Acceptance Using the UTAUT2 Technology Acceptance Model: A Mixed-Methods Approach
Authors: Schretzlmaier Patrik , Hecker Achim , Ammenwerth Elske
Published: May 2023

Background: Mobile health (mHealth) apps are increasingly used in healthcare to support people with chronic diseases such as diabetes. mHealth acceptance is crucial for using them. Due to acceptance problems, however, mHealth apps are not used by all chronic disease patients. To predict user acceptance, technology acceptance models such as UTAUT2 are used. However, UTAUT2 was not explicitly developed for the mHealth context. Objectives: This study investigates if additional health-related constructs could increase the predictive power of the UTAUT2 model. Methods: A mixed-methods design, comprising an initial qualitative methods triangulation study that consisted of a literature search, expert interviews, and patient interviews, and a subsequent quantitative cross-sectional survey with 413 patients was used. Results: The mixed-methods study revealed and validated two new constructs relevant for predicting mHealth acceptance not represented in the UTAUT2 model: “perceived disease threat” and “trust”. Conclusion: The UTAUT2 model was successfully extended by two new constructs relevant to the mHealth context.
Designing a Digital Medical Interview Assistant for Radiology
Authors: Denecke Kerstin , Cihoric Nikola , Reichenpfader Daniel
Published: May 2023

Radiologists rarely interact with the patients whose radiological images they are reviewing due to time and resource constraints. However, relevant information about the patient’s medical history could improve reporting performance and quality. In this work, our objective was to collect requirements for a digital medical interview assistant (DMIA) that collects the medical history from patients by means of a conversational agent and structures as well as provides the collected data to radiologists. Requirements were gathered based on a narrative literature review, a patient questionnaire and input from a radiologist. Based on these results, a system architecture for the DMIA was developed. 37 functional and 17 non-functional requirements were identified. The resulting architecture comprises five components, namely Chatbot, Natural language processing (NLP), Administration, Content Definition and Workflow Engine. To be able to quickly adapt the chatbot content according to the information needs of a specific radiological examination, there is a need for developing a sustainable process for the content generation that considers standardized data modelling as well as rewording of clinical language into consumer health vocabulary understandable to a diverse patient user group.
Smartphone-Based Hyperspectral Imaging – Low-Cost Application for Telemedicine
Authors: Vogt Johanna , Martin Sina , Franke Jörg
Published: May 2023

In this paper we outline a cost-effective design for the improvement of telemedicine applications through a two components concept. A normal smartphone is equipped with a small device containing different filter options, which provide particular spectral information for the identification of skin lesions. By merging the measured spectra, a higher data density and more information can be obtained using an ANN to improve an early diagnosis of skin lesions through telemedicine applications in remote areas.
Immersive Spatial Planning in Healthcare: Developing a Pipeline to Automatically Convert Computer Aided DesignData to Virtual Reality
Authors: Wagner Fabian , Jank Miran , Balz Andrea , Forjan Mathias , Urbauer Philipp
Published: May 2023

Equipping rooms used for medical purposes, like e.g., intensive care units, is an expensive and time-consuming task. In order to avoid extensive subsequent adjustments due to inappropriate layout visualization or geometric conditions difficult to identify in 2D plans, it is of utmost importance to provide an optimal planning environment to future users such as physicians and nurses. In this paper we present the concept of a fully automatized pipeline, which is designed to visualize computer aided design (CAD) data using virtual reality (VR). The immersive VR experience results in improvement of efficiency in the decision-making process during the planning phase due to better spatial imagination. The pipeline was successfully tested with CAD data from existing Intensive Care Units. The results indicate that the pipeline can be a valuable tool in the field of spatial planning in healthcare, due to simple usage and fast conversion of CAD data. The next step will be the development of a plugin for CAD tools to allow for interactions with the CAD models in Virtual Reality, which is not yet possible without manual intervention.
Development of a Digital Interface for Personalized Dosing in Renal Impaired Patients: A Case-Study Using the ACE-Inhibitor Benazepril
Authors: Reinisch Valerie , Paudel Amrit , Pinto Joana T.
Published: May 2023

Background: Personalized dosing regimens have great potential to improve the standard level of care from “one-fits-all” to the “right dose, to the right patient at the right time”. Objectives: Development of a digital interface that can inform healthcare professionals on the dosing of an ACE inhibitor on an individual basis. Methods: A physiologically based pharmacokinetic (PBPK) model and a one-compartment model were implemented for the prodrug benazepril and its metabolite benazeprilat, respectively. In sequence, to capture inter-individual differences the models were extended to a population based one (PopPBPK). Results: Both models predicted the pharmacokinetic data in the observed ranges. Application of the models help identify the factors influencing drug concentrations in the body and to find subgroups of patients, in which a dose adjustment is recommended, or a higher degree of caution is required. Conclusion: The use of the models via a practical user interface can help inform clinical decisions and design optimal dosing based on the individual anthropometric characteristics and stage of renal impairment.
Promoting Healthy Aging Using a Robot Support System and Emotion Recognition
Authors: Jung Oliver , Hollauf Eva , Hornung-Prähauser Veronika , den Uyl Tess , van Zon Kasper
Published: May 2023

The aging population poses challenges such as loneliness, decreased mobility, and medical conditions. To tackle these issues, a proposed robot platform offers personalized well-being behavior change suggestions. Developed through a user-centered process involving surveys and focus groups, and tested with a first prototype, the system is ideal for individuals with “special social needs”. Technical results indicate that emotion recognition is valuable, with attention and valence being key metrics, but user acceptance and quality of facial/speech analysis for elderly users remain challenges.
Using Digital Twins to Support Multiple Stages of the Patient Journey
Authors: Keller Johannes , Lindenmeyer Adrian , Blattmann Malte , Gaebel Jan , Schneider Daniel , Neumuth Thomas , Franke Stefan
Published: May 2023

New possibilities in personalized medicine need to be complemented by clinical decision support systems as well as context-specific applications to be used in clinical routine. We aim to implement a shared technical backend for a large variety of applications in personalized head-and-neck cancer treatment. The infrastructure is conceptualized as a multi-purpose digital twin for cancer treatment. A set of prototypes of clinical applications demonstrates the feasibility of using digital twins to support multiple stages of the patient journey.
Adoption of an Intervention to Promote Physical Activity and Healthy Eating in Brazilian Health Care Settings
Authors: Tomicki Camila , Rech Cassiano Ricardo , Konrad Lisandra Maria , Barbosa Bezerra Juciléia Barbosa , Grontowski Ribeiro Cezar , Schwingel Andiara , Dos Santos Lopes Adalberto Aparecido , Wolker Manta Sofia , Bertoldo Benedetti Tânia Rosane
Published: May 2023

We analyzed the adoption of the community intervention “VAMOS Program” in Primary Health Care (PHC). We carried out a community-based study using mixed-methods in Primary Care Units in Florianopolis, Brazil. We assessed adoption through the RE-AIM framework and conducted interviews and focus groups with 33 health professionals and 26 users participating in the intervention. The Primary Care Units adoption rate was 25%, and the adoption rate among professionals was 80%. We identified three themes related to adoption and we found that organizational factors are challenges that health professionals face when they implement collective actions in PHC but were not inherent factors in adopting VAMOS. We conclude that VAMOS Program has the potential to be offered as a new health promotion tool in PHC.
From Acceptance to Deviation: The China-Japan Relationship and the Control and Prevention of the Manchurian Pneumonic Plague in 1910-1911
Authors:   The Korean Association for the Social History of Medicine, Kim Minsu
Published: May 2023

This paper examines how the Chinese government’s perception of Japan before and after the pneumonic plague epidemic in Manchuria in 1910-1911 influenced China’s disease control and prevention efforts as well as how disease control measures were utilized in the context of the China-Japan relationship. During the New Policy Reform in the Late Qing, the Qing government established a government-led health care system, adopted from the Japanese model, to enhance national prosperity. In Manchuria, the central government’s plan was implemented immediately, in response to Japan’s attempt to expand its influence through disease control, which had been in place since the late 19th century.
During the pneumonic plague in Manchuria in 1910-1911, cooperation and containment between Qing and Japan continued over the initiatives in epidemic control. The Japanese authorities approached the Qing government’s anti-epidemic efforts based on an assumed image of “Japanese assisting Chinese.” However, the Qing government sought to thwart it by implementing systematic and autonomous measures for disease control. Furthermore, at the Japan-Qing Joint Epidemic Prevention Conference, the Qing government constrained Japanese authorities’ involvement in epidemic control, and through the International Plague Conference, it internationalized the issue of pneumonic plague prevention.
The government of the Republic of China that succeeded Qing accepted resolutions submitted by the representatives who participated in the International Plague Conference, and set up the North Manchurian Plague Prevention Service. The North Manchurian Plague Prevention Service, which had to make achievements to garner international recognition, mostly appointed members from the British-American faction, who were considered to have a higher level of medical skill than those of the Japanese faction that held the majority in the Western medical community in China at the time. This was in line with desire of the British-American faction, who sought to expand their influence in China.
As anti-Japanese sentiments increased after Japan’s Twenty-One Demands in 1915, the central government of the Republic of China appointed members of the British- American faction as field practitioners to take leadership in epidemic prevention. Thus, China was able to distance itself from Japan by going through a wide range of options for disease control and prevention.
A Case Study of the Management Information System in the Coffee Industry in SW Ethiopia
Authors: Birhan Mequanint
Published: May 2023

The 11th regional state in southwest Ethiopia, the South West Ethiopia Peoples' Region (SWER), is well-reachable for various coffee species and cultivation. According to a tradition, in the ninth century, the goat herder Kaldi first saw the potential of these well-loved beans in one of the region's zones, namely Kefa. The research article's main goal is to examine the impact of management information systems (MIS) on the coffee farm sector in SWER. Direct site observation and secondary data reviews on the subject were the methods used to obtain the data. The review's findings demonstrated that using management information systems worked substantially better when important industry informants participated actively and made decisions about stress. The SWER which was coffee-abundant and developed using traditional ways, should provide information management synchronization systems. The birthplace of coffee (Ethiopia) could use technologies for assessing MIS implementation tasks to remove difficulty at high speed in the intelligibility levels. Triple constraints like time, cost, and quality of information must be managed.
ANALISIS EFISIENSI PRODUKSI KELAPA SAWIT DI PT. KARYA TANAH SUBUR : STUDI KASUS DI AFDELING I, KABUPATEN ACEH BARAT
Authors: Adiyani Fitri , Agustiar Agustiar
Published: May 2023

This study aims to determine the analysis of the efficiency of palm oil production factors in Afdeling I at PT. Karya Tanah Subur, Kaway District xvi West Aceh Regency. The method of data collection in this research is to use primary data and secondary data. This research was conducted at JL. Gempong-Tutut, Padang Sikabu Village, Kaway XVI District, Aceh Regency. The research location was carried out at PT. Karya Tanah Subur in Afdeling I starting in February 2022 until May 2022. Data were analyzed using production analysis with this research being quantitative as well as survey through interviews and using surposive sampling technique. The results of this study show that oil palm production in Afdeling I is 261.130 per month while the total production of palm oil in 2022 is 350,428 per month.
POTENSI DAUN BAWANG MERAH (Allium cepa L) SEBAGAI LARVASIDA ALAMI UNTUK MEMBUNUH JENTIK NYAMUK AEDES AEGYPTY
Authors: Yani Evi Dewi , Ridhwan Muhammad , Husna Husna , Masyudi Masyudi , Rafsanjani Teuku Muhammad
Published: May 2023

Pemberantasan jenitik nyamuk aedes aegypty menggunakan serbuk Abate dalam kurun waktu lama secara terus menerus ternyata dapat mengakibatkan kematian hewan yang bukan target, hilang atau matinya musuh alami, kerusakan lingkungan berupa ketidakseimbangan ekosistem dan resistensi populasi Aides. Pemanfaatan bahan alam sebagai upaya alternatif yang ramah lingkungan dan tidak berbahaya bagi organisme lainnya perlu dilakukan. Penelitian terdahulu diketahui kulit bawang merah (Aliium cepa L) mengandung senyawa flavonoid yang dapat bersifat larvasida, alkaloid, polifenol, seskuiterpenoid, monoterpenoid, steroid, triterpenoid, acetogenin serta kuinon. Pada penelitian ini Peneliti mengkaji kandungan dalam daun bawang merah dan mengujinya pada larva nyamuk Aides aegepty. Jenis penelitian ini adalah eksperimental, yang dilakukan di laboratorium MIPA Universitas Serambi Mekkah, daun bawang merah di ambil dari petani bawang yang ada di Kabupaten Aceh Selatan. Hasil penelitian 70% telah dilakukan proses ekstraksi daun bawang menggunakan pelarut ethanol, hasil uji fitokimia ekstrak daun bawang Aceh mengandung senyawa flavonoid, saponin, tannin, alkaloid, steroid dan triterpenoid. Senyawa senyawa ini berpotensi sebagai larvasida alami yang dapat membunuh larva nyamuk aedes aegypti.
Probiotic feed additive “EnzActive” against the background of hay-type fattening of young bulls
Authors: Mil O. O. , Pivtorak Ya. I.
Published: May 2023

Standardized feeding of young cattle should be based on scientifically based standards, guaranteeing their genetic productivity potential, rational use of fodder resources, and proper feed payment with meat products. The current situation regarding the rationing of livestock feeding in global and domestic, both scientific and industrial practices, has fundamentally changed, which requires a significant revision of the traditional provisions on the organization of standardized feeding and feeding of farm animals. At the same time, the conceptual requirements for the organization of standardized feeding of young livestock should be based on the generalization of world experience in need of animals for energy, nutrients, and biologically active substances, taking into account the age period of fattening with an emphasis on the quality and biosafety of products. In the conditions of intensive production of meat products, to ensure high productivity, it is impossible to do without using feed products of natural substance, which should include additives with a purely biological effect. One of these includes the feed additive “EnzActive”, which contains a unique formula of a combination of biotic and enzymatic action, which consists of live yeast of the genus Saccharomyces cerevisiae, and a complex of six enzymes: protease, cellulose, xynalose, α-amylase, ß-gluconase and phytase. The research was based on optimizing the standardized feeding of fattening young animals on hay-type rations using the probiotic feed additive “EnzActive” based on 8 g/head per day. The research was conducted on Simmental bulls in the conditions of the “Pchany-Denkovych” farm of the Stryi district of the Lviv region. It was established that the use of the probiotic supplement “EnzActive” against the background of hay-type feeding contributed to the improvement of the intensity of the vital activity of the physiologically helpful microflora of the rumen, which had a stimulating effect in the processes of additional assimilation of nutrients. A positive result was obtained regarding the level of average daily growth and functional features of rumen microflora, the final period of fattening. Thus, based on the results of our research, it is possible to recommend introducing the hay type with the inclusion of probiotic feed additive “EnzActive” at the rate of 8 g/head into the intensive livestock technology fattening a day. No adverse side effects of “EnzActive” bio-additives on the general functional condition of young bull's residents were found.
Inventarizacija samonikle flore na području grada
Zaprešića
Authors: Dujmović Purgar Dubravka , Skenderović Babojelić Martina , Jurić Maja , Kušen Mihael , Židovec Vesna
Published: May 2023

Samoniklo bilje je bilje koje je sastavni dio prirode i raste bez ikakvog ljudskog utjecaja. Ono prati čovjeka kroz povijest jer u sebi sadrži ljekovite tvari koje pomažu pri liječenju raznih bolesti, koristi se kao hrana ili dopuna obrocima, ali i kao začin. Kao što je izvor hrane za ljude tako je i izvor hrane za mnoge životinje i kukce (pčele). Ljudi ga koriste i u ukrasne svrhe da njime uljepšaju životni prostor. Pri njegovoj uporabi treba pripaziti i na otrovnost s obzirom da su neke vrste vrlo otrovne te mogu izazvati ozbiljne zdravstvene probleme, uključujući i smrt. U posljednje vrijeme sve više se istražuje i koristi samoniklo bilje. Na sedam različitih lokacija u gradu Zaprešiću tijekom 2021. godine provedena je inventarizacija samoniklih biljnih vrsta. Pri tome je utvrđena 171 biljna vrsta iz 57 porodica. Najzastupljenije su bile biljke iz porodica Fabaceae, Brassicaceae, Poaceae i Rosaceae. Prema trajanju života dominiraju zeljaste trajnice, a u životnim oblicima dominiraju hemikriptofiti. Najviše biljnih vrsta je euroazijskog porijekla te prevladavaju vrste široke rasprostranjenosti i europskog flornog elementa. Inventarizacijom je utvrđena prisutnost devet invazivnih biljnih vrsta, te dvije strogo zaštićene biljne vrste. S obzirom na uporabnu vrijednost najzastupljenije su medonosne biljne vrste (94 vrste). Slijede ljekovite biljne vrste (86 vrsta), zatim jestive (77 vrsta), ukrasne (53 vrste) i otrovne biljne vrste (43 vrste), a najmanje ima začinskih biljnih vrsta (12). Važno je istaknuti da je na relativno malom području zastupljen velik broj vrsta različite uporabne vrijednosti.
Novi
podaci o rasprostranjenosti i staništima ljekovitih svojti papratnjača na području Slavonije
Authors: Sabo Nikolina , Miloloža Tihana , Krstin Ljiljana , Katanić Zorana , Žuna Pfeiffer Tanja , Šag Matej
Published: May 2023

Istraživanje ljekovitih svojti papratnjača provedeno je na tri lokaliteta na području Slavonije (istočna Hrvatska). Odabrani lokaliteti (Arboretum Lisičine, Park šuma Jankovac i grad Osijek) razvrstani su u dvije kategorije s obzirom na stupanj urbanizacije: 1) prirodna staništa/ruralna sredina i 2) urbana sredina. Zabilježeno je ukupno 12 svojti ljekovitih papratnjača unutar sedam porodica, od kojih su najzastupljenije svojte iz porodica Equisetaceae i Aspleniaceae. Samo jedna svojta bila je prisutna na svim lokalitetima. Ustanovljena je veća raznolikost svojti na prirodnim staništima. Zbog izraženih ljekovitih i nutritivnih svojstava kao i važnosti papratnjača u fitoremedijaciji, potrebno je provoditi daljnja istraživanja njihove raznolikosti u urbanim sredinama te educirati širu javnost o važnosti i mogućnostima primjene i uzgoja ove skupine biljaka u urbanim sredinama.
Ukrasna
i uporabna vrijednost različitih vrsta roda Vaccinium
Authors: Zrnić Anja , Jeran Nina , Židovec Vesna
Published: May 2023

U Hrvatskoj nalazimo tri samonikle vrste roda Vaccinium te jednu stranu vrstu u uzgoju. Iako u svijetu nailazimo na primjenu roda u krajobraznom oblikovanju, u Hrvatskoj je poznat uzgoj isključivo u prehrambene svrhe. Pregledom morfoloških, ukrasnih i uporabnih vrijednosti 14 vrsta borovnica i brusnica (Vaccinium spp.) porijeklom iz različitih dijelova svijeta, analiziran je njihov potencijal i specifičnosti za primjenu u krajobraznom oblikovanju. Sve analizirane vrste odlikuju se određenim visoko reprezentativnim ukrasnim vrijednostima (habitus, proljetna i jesenja boja lista, boja stabljike, cvjetovi i plodovi) i uporabnim svojstvima zbog kojih predstavljaju kvalitetne vrste za uporabu u uređenju površina zelenila. S obzirom na svoja uzgojna svojstva, pogodne su za upotrebu u Hrvatskoj. Mogu se koristiti u obliku pokrivača tla, živih ograda, bordura, ali i na samostalnim gredicama te kao soliteri i u skupinama. S obzirom na jestive plodove kao dodatnu vrijednost, mogu se integrirati u tzv. jestivi krajolik (engl. edible landscape), način estetskog oblikovanja površine zelenila jestivim biljnim vrstama. Vrste roda Vaccinium najprikladnije su za uređenje privatnih vrtova i ograđenih javnih prostora udaljenih od prometnica poput vrtova u sklopu dječjih vrtića i škola, domova za starije, urbanih vrtova, parkova u ruralnim sredinama i slično.
ТРАНСФОРМАЦІЯ СИСТЕМИ УПРАВЛІННЯ ВНУТРІШНЬОГО АУДИТУ В УМОВАХ ГЛОБАЛЬНИХ КРИЗ ТА ВІЙНИ
Authors: Наумова Т. А. , Акімова Н. С. , Кирильєва Л. О.
Published: May 2023

Розглянуто необхідність дослідження організаційно-методичних аспектів системи управління внутрішнього аудиту та визначено шляхи її трансформації в умовах глобальних криз та війни. На підставі проведеного моніторингу існуючих концепцій розвитку внутрішнього аудиту, визначено, що внутрішній (управлінський) аудит є важливим елементом у системи управління в цілому. Критичний аналіз та зіставлення різних точок зору вчених та практиків, дозволило нам визначити компромісний підхід до організації внутрішнього контролю, окреслений його завданнями. Для українських організацій об’єкти внутрішнього аудиту можуть бути різними, наприклад окремі підрозділи або ділянки, в залежності від особливостей суб’єкта і вимог керівництва і (або) власників. У зв’язку з цим, нами були виділені та розширені функції внутрішнього аудиту тому, що відбулася зміна об’єктів аудиту в період глобальних криз та війни. Власники та користувачі інформації сподіваються отримати від внутрішніх аудиторів рекомендації для прийняття економічних рішень, експертизу бізнесу, компетентну консультацію з різних питань, вичерпну інформацію про реальну життєздатність компанії. З урахуванням нестабільної політичної та економічної ситуації в країні визначено роль і функції внутрішнього аудиту. Досліджені довгострокові наслідки війни для професії внутрішнього аудитора, тобто визначено, яким чином повоєнний стан аудиторської діяльності вплине на штат служб внутрішнього аудиту та систему внутрішнього контролю на чолі з її керівником. Зміна об’єктів аудиту, яка обумовлена впливом глобальних криз та війни призводить до необхідності зміни системи управління внутрішнім аудитом в цілому. У цьому зв’язку ми провели порівняльну характеристику за відповідними критеріями функцій та ролі внутрішнього аудиту до та під час воєнних дій в Україні. Доведено необхідність розробки Положення про організацію внутрішнього аудиту на підприємствах в умовах воєнного стану, з урахуванням дистанційної форми праці та зниження можливих ризиків і недоліків, які мають місце за таких умов, що надасть можливість керівництву господарюючого суб’єкта приймати ефективні управлінські рішення і в повоєнний час.
КРАУДСОРСІНГ – ЗАСІБ РОЗВИТКУ ЦИФРОВОЇ ТОРГІВЛІ НА ГЛОБАЛЬНИХ РИНКАХ
Authors: Шевченко І. О.
Published: May 2023

В роботі розкрито сутнісну характеристику краудсорсингу шляхом розкриття категоріального апарату, прослідковано взаємозв’язок краудсорсингу з цифровою торгівлею. У статті зроблено спробу осмислення процесів трансформації ринку праці та розвитку цифрової торгівлі. В роботі виявлено характерні риси краудсорсингу які були б притаманні розвитку цифрової торгівлі. Метою статті є виокремлення краудсорсингу як нового феномену, який сприяє розвитку цифрової торгівлі шляхом відображення технологічних та соціально-економічних зрушень. Як приклад розглянуто краудсорсинг як із форм трудової діяльності, специфікою якої є залучення великих груп людей у процес створення нової вартості у віртуальному просторі. Методи дослідження. У процесі дослідження використовувалися методи логічного аналізу, зіставлення та узагальнення. Інформаційну базу формували наукові статті, матеріали періодичного друку, інформаційні та аналітичні матеріали. Результати. У ході аналізу було виділено чотири групи факторів (технологічні, глобалізаційні, інституційні, соціально-демографічні), які у своєму взаємозв'язку та взаємозалежності формують передумови змін у змісті та характері праці. Декомпозиція змістового простору краудсорсингу з позицій професійних вимог до працівника, сутності діяльності, можливості використання його результатів виконавцем, а також характеру винагороди за працю призвела до висновку про різнорідну структуру розглянутої форми зайнятості. Виявлена гетерогенність змісту праці та трудових відносин у цифровій економіці вимагає формування адекватного інституційного середовища, що враховує такі ризики та загрози нових форм зайнятості. Практична значимість результатів полягає у використані в процесі подальшого аналізу цифрової торгівлі, , проектування основних підходів до визначення рівня розвитку цифрової торгівлі. Ці результати є основою подальшої перспективи до розробки відділу внутрішнього просування цифрової трансформації як державного органу забезпечення розвитку цифрової торгівлі.
USING CRYPTOCURRENCIES IN FINANCING SUSTAINABLE DEVELOPMENT GOAL PROJECTS: SWOT ANALYSIS
Authors: Білоскурський Р. Р.
Published: May 2023

The interest and adoption of cryptocurrencies, such as Bitcoin and Ethereum, have significantly increased as a medium of payment and investment. At the same time, the international community has set a list of Sustainable Development Goals (SDGs) to be achieved by 2030, which includes eradicating poverty, protecting the planet, and ensuring peace and prosperity for everyone. One of the most significant challenges in achieving these SDGs is financing the necessary projects to implement them. Traditional financing sources, such as government budgets and private investments, may not be sufficient to cover the enormous costs associated with achieving the SDGs. Therefore, there is a need to explore alternative financing mechanisms to support the implementation of the SDGs. Cryptocurrencies represent a potential alternative source of funding for SDG projects. However, the lack of regulation and the high volatility of cryptocurrency prices may create uncertainty and risk for investors and project stakeholders. Examples of the use of cryptocurrencies in various SDG projects to enable fast and low-cost cross-border transactions are presented. The feasibility of using cryptocurrencies as a financing mechanism for SDG projects, a comprehensive SWOT analysis of the use of cryptocurrencies in financing SDG projects, potential problems and opportunities related to the use of cryptocurrencies for financing SDG projects, practical recommendations for policy makers, project developers and investors who are interested in using cryptocurrencies for financing SDG projects are discussed in the article. To address this issue, this article aims to conduct a SWOT analysis to evaluate the strengths, weaknesses, opportunities, and threats of using cryptocurrencies as a financing mechanism for SDG projects. The analysis will provide valuable insights into the potential benefits and drawbacks of utilizing cryptocurrencies for SDG project financing and identify strategies to mitigate risks and maximize opportunities. Ultimately, this research aims to contribute to the broader conversation around alternative financing mechanisms for sustainable development projects.