bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Yes-Associated Protein 1 Is Activated and Functions as an Oncogene in Meningiomas
Authors: Baia Gilson S. , Caballero Otavia L. , Orr Brent A. , Lal Anita , Ho Janelle S. Y. , Cowdrey Cynthia , Tihan Tarik , Mawrin Christian , Riggins Gregory J.
Published: April 2023

PDF file - 212K, Immunohistochemistry of YAP1 expression in various cores of control normal human tissue
Supplementary Figure 3 from Fibroblast Growth Factor-2 Is an Important Factor that Maintains Cellular Immaturity and Contributes to Aggressiveness of Osteosarcoma
Authors: Shimizu Takatsune , Ishikawa Tomoki , Iwai Sayaka , Ueki Arisa , Sugihara Eiji , Onishi Nobuyuki , Kuninaka Shinji , Miyamoto Takeshi , Toyama Yoshiaki , Ijiri Hiroshi , Mori Hajime , Matsuzaki Yumi , Yaguchi Tomonori , Nishio Hiroshi , Kawakami Yutaka , Ikeda Yasuo , Saya Hideyuki
Published: April 2023

PDF file - 83K
Supplementary Figure 2 from Fibroblast Growth Factor-2 Is an Important Factor that Maintains Cellular Immaturity and Contributes to Aggressiveness of Osteosarcoma
Authors: Shimizu Takatsune , Ishikawa Tomoki , Iwai Sayaka , Ueki Arisa , Sugihara Eiji , Onishi Nobuyuki , Kuninaka Shinji , Miyamoto Takeshi , Toyama Yoshiaki , Ijiri Hiroshi , Mori Hajime , Matsuzaki Yumi , Yaguchi Tomonori , Nishio Hiroshi , Kawakami Yutaka , Ikeda Yasuo , Saya Hideyuki
Published: April 2023

PDF file - 406K
Supplementary Figure 1 from Targeting Abnormal DNA Repair in Therapy-Resistant Breast Cancers
Authors: Tobin Lisa A. , Robert Carine , Nagaria Pratik , Chumsri Saranya , Twaddell William , Ioffe Olga B. , Greco George E. , Brodie Angela H. , Tomkinson Alan E. , Rassool Feyruz V.
Published: April 2023

PDF file - 336K
Supplementary Figure Legends 1-2 from PRSS3/Mesotrypsin Is a Therapeutic Target for Metastatic Prostate Cancer
Authors: Hockla Alexandra , Miller Erin , Salameh Moh'd A. , Copland John A. , Radisky Derek C. , Radisky Evette S.
Published: April 2023

PDF file - 74K
Supplementary Methods from Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells
Authors: Minami Daisuke , Takigawa Nagio , Takeda Hiromasa , Takata Minoru , Ochi Nobuaki , Ichihara Eiki , Hisamoto Akiko , Hotta Katsuyuki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

PDF file - 79K
Supplementary Figure Legend from Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells
Authors: Minami Daisuke , Takigawa Nagio , Takeda Hiromasa , Takata Minoru , Ochi Nobuaki , Ichihara Eiki , Hisamoto Akiko , Hotta Katsuyuki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

PDF file - 78K
Supplementary Figure 5 from Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells
Authors: Minami Daisuke , Takigawa Nagio , Takeda Hiromasa , Takata Minoru , Ochi Nobuaki , Ichihara Eiki , Hisamoto Akiko , Hotta Katsuyuki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

PDF file - 61K, Western blot showing RAD51 and RPA levels in H1650, H1650PTEN+, PC-9 and PC-9PTEN- cells.
Supplementary Figure 3 from Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells
Authors: Minami Daisuke , Takigawa Nagio , Takeda Hiromasa , Takata Minoru , Ochi Nobuaki , Ichihara Eiki , Hisamoto Akiko , Hotta Katsuyuki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

PDF file - 147K, A: Subcellular localization of RPA and γH2AX in H1650 or H1650PTEN+ cells after exposure of olaparib (20 μM). B: PTEN deficiency resulted in significant reduction in RPA focus formation after exposure of cisplatin (10 μM) or/and olaparib (20 μM), or irradiation (10 Gy) compared to H1650PTEN+ cells (P < 0.05) although γH2AX was similarly increased in both cells.
Supplementary Figure 4 from Group I p21-Activated Kinases (PAKs) Promote Tumor Cell Proliferation and Survival through the AKT1 and Raf–MAPK Pathways
Authors: Menges Craig W. , Sementino Eleonora , Talarchek Jacqueline , Xu Jinfei , Chernoff Jonathan , Peterson Jeffrey R. , Testa Joseph R.
Published: April 2023

PDF file - 27K, Expression of PID inhibits PAK phosphorylation, cell viability (MTS assay) and G418-resistant colony formation in Meso-17 cells
Supplementary Materials and Methods from Molecular Hierarchy of Heparin-Binding EGF-like Growth Factor–Regulated Angiogenesis in Triple-Negative Breast Cancer
Authors: Yotsumoto Fusanori , Tokunaga Eriko , Oki Eiji , Maehara Yoshihiko , Yamada Hiromi , Nakajima Kyoko , Nam Sung Ouk , Miyata Kohei , Koyanagi Midori , Doi Keiko , Shirasawa Senji , Kuroki Masahide , Miyamoto Shingo
Published: April 2023

PDF File - 117K, Supplementary Materials and Methods, Supplementary References and Supplementary Figure legends.
Figure S3 from Mitochondria Participate in Chemoresistance to Cisplatin in Human Ovarian Cancer Cells
Authors: Zampieri Luca X. , Grasso Debora , Bouzin Caroline , Brusa Davide , Rossignol Rodrigue , Sonveaux Pierre
Published: April 2023

Figure S3 shows that inhibiting cell respiration or glycolysis does not selectively kill cisplatin-resistant human ovarian cancer cells.
Supplementary Figure 1 from Nanoscale Tuning of VCAM-1 Determines VLA-4–Dependent Melanoma Cell Plasticity on RGD Motifs
Authors: Amschler Katharina , Kossmann Eugen , Erpenbeck Luise , Kruss Sebastian , Schill Tillmann , Schön Margarete , Möckel Sigrid M.C. , Spatz Joachim P. , Schön Michael P.
Published: April 2023

MeWo melanoma cell spreading is controlled by VCAM-1 density in a reciprocal fashion.
Supplementary Figures S1-S3 from Menin Promotes the Wnt Signaling Pathway in Pancreatic Endocrine Cells
Authors: Chen Gao , A Jingbo , Wang Min , Farley Steven , Lee Lung-Yi , Lee Lung-Ching , Sawicki Mark P.
Published: April 2023

Supplementary Figures S1-S3 from Menin Promotes the Wnt Signaling Pathway in Pancreatic Endocrine Cells
Supplementary Video 3 from The Heterochronic microRNA let-7 Inhibits Cell Motility by Regulating the Genes in the Actin Cytoskeleton Pathway in Breast Cancer
Authors: Hu Xiaowen , Guo Jinyi , Zheng Lan , Li Chunsheng , Zheng Tim M. , Tanyi Janos L. , Liang Shun , Benedetto Chiara , Mitidieri Marco , Katsaros Dionyssios , Zhao Xia , Zhang Youcheng , Huang Qihong , Zhang Lin
Published: April 2023

AVI file - 173K, let-7b inhibits breast cancer cell motility�would healing assay.
Supplementary Figure Legends 1-3 from A Novel 19q13 Nucleolar Zinc Finger Protein Suppresses Tumor Cell Growth through Inhibiting Ribosome Biogenesis and Inducing Apoptosis but Is Frequently Silenced in Multiple Carcinomas
Authors: Cheng Yingduan , Liang Pei , Geng Hua , Wang Zhaohui , Li Lili , Cheng Suk Hang , Ying Jianming , Su Xianwei , Ng Ka Man , Ng Margaret H.L. , Mok Tony S.K. , Chan Anthony T.C. , Tao Qian
Published: April 2023

PDF file - 61K
Supplementary Figure S1 from Targeted Imaging of Colonic Tumors in Smad3−/− Mice Discriminates Cancer and Inflammation
Authors: Deane Natasha G. , Manning H. Charles , Foutch A. Coe , Washington M. Kay , Aronow Bruce A. , Bornhop Darryl J. , Coffey Robert J.
Published: April 2023

Supplementary Figure S1 from Targeted Imaging of Colonic Tumors in Smad3−/− Mice Discriminates Cancer and Inflammation
Supplementary Data from A Novel DNMT3B Splice Variant Expressed in Tumor and Pluripotent Cells Modulates Genomic DNA Methylation Patterns and Displays Altered DNA Binding
Authors: Gopalakrishnan Suhasni , Van Emburgh Beth O. , Shan Jixiu , Su Zhen , Fields C. Robert , Vieweg Johannes , Hamazaki Takashi , Schwartz Philip H. , Terada Naohiro , Robertson Keith D.
Published: April 2023

Supplementary Data from A Novel DNMT3B Splice Variant Expressed in Tumor and Pluripotent Cells Modulates Genomic DNA Methylation Patterns and Displays Altered DNA Binding
Supplementary Data from Post-transcriptional Regulation of P-Glycoprotein Expression in Cancer Cell Lines
Authors: Gómez-Martínez Angeles , García-Morales Pilar , Carrato Alfredo , Castro-Galache María D. , Soto José L. , Carrasco-García Estefanía , García-Bautista Miriam , Guaraz Patricia , Ferragut José A. , Saceda Miguel
Published: April 2023

Supplementary Data from Post-transcriptional Regulation of P-Glycoprotein Expression in Cancer Cell Lines
Supplementary Table S1 from Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor
Authors: Jones Robert A. , Campbell Craig I. , Petrik James J. , Moorehead Roger A.
Published: April 2023

Supplementary Table S1 from Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor
Supplementary Tables S1-S4 from Neutral Sphingomyelinase-3 Is a DNA Damage and Nongenotoxic Stress-Regulated Gene That Is Deregulated in Human Malignancies
Authors: Corcoran Chad A. , He Qin , Ponnusamy Suriyan , Ogretmen Besim , Huang Ying , Sheikh M. Saeed
Published: April 2023

Supplementary Tables S1-S4 from Neutral Sphingomyelinase-3 Is a DNA Damage and Nongenotoxic Stress-Regulated Gene That Is Deregulated in Human Malignancies
Supplementary Figures S1-S2 from Epigenetic Down-Regulation of ARF Expression Is a Selection Step in Immortalization of Human Fibroblasts by c-Myc
Authors: Benanti Jennifer A. , Wang Myra L. , Myers Hadley E. , Robinson Kristin L. , Grandori Carla , Galloway Denise A.
Published: April 2023

Supplementary Figures S1-S2 from Epigenetic Down-Regulation of ARF Expression Is a Selection Step in Immortalization of Human Fibroblasts by c-Myc
Supplementary Table 3 from SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth
Authors: Lazar Ikrame , Fabre Bertrand , Feng Yongmei , Khateb Ali , Turko Patrick , Martinez Gomez Julia M. , Frederick Dennie T. , Levesque Mitchell P. , Feld Lea , Zhang Gao , Zhang Tongwu , James Brian , Shklover Jeny , Avitan-Hersh Emily , Livneh Ido , Scortegagna Marzia , Brown Kevin , Larsson Ola , Topisirovic Ivan , Wolfenson Haguy , Herlyn Meenhard , Flaherty Keith , Dummer Reinhard , Ronai Ze'ev A.
Published: April 2023

Supplementary Table S3: List of the genes that were identified by RNAseq to be significantly deregulated upon SPANX KD.
Supplemental Figure S3 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
Authors: Crowe Matthew S. , Zavorotinskaya Tatiana , Voliva Charles F. , Shirley Matthew D. , Wang Yanqun , Ruddy David A. , Rakiec Daniel P. , Engelman Jeffery A. , Stuart Darrin D. , Freeman Alyson K.
Published: April 2023

Supplementary Figure S3 shows overexpression of MAPK1 (ERK2) in human melanoma cell lines compared to MAPK3 (ERK1) and cell lines of other lineages, a correlation of ERK2 dependency with MAPK1 (ERK2) mRNA expression, and ERK1/2 protein expression across a select panel of cell lines.
Figure S1: L-ascorbic acid (L-AA) exposure enhances 5hmC accumulation to a greater extent in TET2-WT TF1 cells. from 5-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells
Authors: Reilly Brian M. , Luger Timothy , Park Soo , Lio Chan-Wang Jerry , González-Avalos Edahí , Wheeler Emily C. , Lee Minjung , Williamson Laura , Tanaka Tiffany , Diep Dinh , Zhang Kun , Huang Yun , Rao Anjana , Bejar Rafael
Published: April 2023

Cells were treated with 100uM L-AA or vehicle 24hrs before DNA isolation. A) 5hmC dot blot for L-AA treated or untreated Cells. B) Standard curve of 5hmC densitometric signal vs. pmol (calculated from 5hmC standard with known 5hmC amount). C) Quantification of dot blot signal for TET2-WT and KO cells +/- L-AA.
Figure S3 from p53 Is Not Required for High CIN to Induce Tumor Suppression
Authors: Funk Laura C. , Wan Jun , Ryan Sean D. , Kaur Charanjeet , Sullivan Ruth , Roopra Avtar , Weaver Beth A.
Published: April 2023

Figure S3 shows that reduction of CENP-E extends tumor latency only in tumors where it causes high CIN.
Supplementary Figure 4 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Authors: Slotkin Emily K. , Bowman Anita S. , Levine Max F. , Dela Cruz Filemon , Coutinho Diego F. , Sanchez Glorymar I. , Rosales Nestor , Modak Shakeel , Tap William D. , Gounder Mrinal M. , Thornton Katherine A. , Bouvier Nancy , You Daoqi , Gundem Gunes , Gerstle Justin T. , Heaton Todd E. , LaQuaglia Michael P. , Wexler Leonard H. , Meyers Paul A. , Kung Andrew L. , Papaemmanuil Elli , Zehir Ahmet , Ladanyi Marc , Shukla Neerav
Published: April 2023

Supplementary Figure 4 shows data related to FGFR4 inhibition in DSRCT and control models
Supplementary Data S4 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics
Authors: Smith Kaitlyn H. , Budhraja Amit , Lynch John , Roberts Kathryn , Panetta John C. , Connelly Jon P. , Turnis Meghan E. , Pruett-Miller Shondra M. , Schuetz John D. , Mullighan Charles G. , Opferman Joseph T.
Published: April 2023

Synergy analysis of BTdCPU and BH3-mimetics in BCR-ABL+ B-ALL cells
Supplementary Data S3 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics
Authors: Smith Kaitlyn H. , Budhraja Amit , Lynch John , Roberts Kathryn , Panetta John C. , Connelly Jon P. , Turnis Meghan E. , Pruett-Miller Shondra M. , Schuetz John D. , Mullighan Charles G. , Opferman Joseph T.
Published: April 2023

Synergy analysis of DHA and BH3-mimetics in BCR-ABL+ B-ALL cells
Supplementary Data S2 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics
Authors: Smith Kaitlyn H. , Budhraja Amit , Lynch John , Roberts Kathryn , Panetta John C. , Connelly Jon P. , Turnis Meghan E. , Pruett-Miller Shondra M. , Schuetz John D. , Mullighan Charles G. , Opferman Joseph T.
Published: April 2023

Activation of integrated stress response by DHA or succinylacetone
Supplementary Table S1 from EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma
Authors: Jiménez Jennifer A. , Apfelbaum April A. , Hawkins Allegra G. , Svoboda Laurie K. , Kumar Abhijay , Ruiz Ramon Ocadiz , Garcia Alessandra X. , Haarer Elena , Nwosu Zeribe C. , Bradin Joshua , Purohit Trupta , Chen Dong , Cierpicki Tomasz , Grembecka Jolanta , Lyssiotis Costas A. , Lawlor Elizabeth R.
Published: April 2023

Primer Sequences
Supplementary Figure S4 from EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma
Authors: Jiménez Jennifer A. , Apfelbaum April A. , Hawkins Allegra G. , Svoboda Laurie K. , Kumar Abhijay , Ruiz Ramon Ocadiz , Garcia Alessandra X. , Haarer Elena , Nwosu Zeribe C. , Bradin Joshua , Purohit Trupta , Chen Dong , Cierpicki Tomasz , Grembecka Jolanta , Lyssiotis Costas A. , Lawlor Elizabeth R.
Published: April 2023

Supplementary Figure S4. Publicly Available RNA-Seq Data of EWS-FLI1 Knockdown.
Figure S4 from Hypoxic Induction of Exosome Uptake through Proteoglycan-Dependent Endocytosis Fuels the Lipid Droplet Phenotype in Glioma
Authors: Cerezo-Magaña Myriam , Christianson Helena C. , van Kuppevelt Toin H. , Forsberg-Nilsson Karin , Belting Mattias
Published: April 2023

Confocal microscopy images of U87 MG cells showing (A) decreased membrane cholesterol staining (Filipin) by MCD treatment, and (B) increased CtxB (red) internalization in hypoxia (H) that is inhibited by MCD. (C) Confocal microscopy images of N and H U87 MG cells showing increased α-HS internalization in H that is sensitive to MCD treatment.
Supplementary Figures 1-6 from The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth
Authors: Liu Xi , Lu Yun , Chen Zibo , Liu Xiuxia , Hu Weiguo , Zheng Lin , Chen Yulong , Kurie Jonathan M. , Shi Mi , Mustachio Lisa Maria , Adresson Thorkell , Fox Stephen , Roszik Jason , Kawakami Masanori , Freemantle Sarah J. , Dmitrovsky Ethan
Published: April 2023

S1. USP18 regulates metabolism-related proteins by Reverse Phase Protein Array (RPPA) in A549 lung cancer cells. S2. This figure compares CellTiter-Glo assays and manual counting for lung cancer cell proliferation at day 3. S3. The mRNA expression profiles of USP18, ATGL and UCP1 in the indicated different cancer types using TCGA database. S4. Combined USP18, ATGL and UCP1 expression profiles in cancers that were using TCGA database. S5. USP18 regulates lipid metabolism in lung cancer cell lines. S6. Differential ATGL expression profiles by immunohistochemical staining of human lung cancer cases using the Human Protein Atlas.
Figure S6 from Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM
Authors: Ohkawa Yuki , Wade Anna , Lindberg Olle R. , Chen Katharine Y. , Tran Vy M. , Brown Spencer J. , Kumar Anupam , Kalita Mausam , James C. David , Phillips Joanna J.
Published: April 2023

HS structure including 6-O-sulfation alters cell surface PDGF-BB binding.
Supplementary Figure S4 from A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma by Suppressing LSD1
Authors: Wirawan Aditya , Tajima Ken , Takahashi Fumiyuki , Mitsuishi Yoichiro , Winardi Wira , Hidayat Moulid , Hayakawa Daisuke , Matsumoto Naohisa , Izumi Kenta , Asao Tetsuhiko , Ko Ryo , Shimada Naoko , Takamochi Kazuya , Suzuki Kenji , Abe Masaaki , Hino Okio , Sekido Yoshitaka , Takahashi Kazuhisa
Published: April 2023

Supplementary Figure S4 shows that MFGE8 regulates the FAK pathway.
Figure S4 from Adaptor Protein ShcD/SHC4 Interacts with Tie2 Receptor to Synergistically Promote Glioma Cell Invasion
Authors: Tilak Manali , Alural Begüm , Wismer Sarah E. , Brasher Megan I. , New Laura A. , Sheridan Steven D. , Perlis Roy H. , Coppolino Marc G. , Lalonde Jasmin , Jones Nina
Published: April 2023

Localization of TKS5 with F-actin punctae in U87 cells expressing both wild-type ShcD and Tie2.
Supplementary Figures 1-13 from Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway
Authors: Zhang Hui-Juan , Chang Wen-Jing , Jia Cai-Yun , Qiao Ling , Zhou Jing , Chen Qing , Zheng Xiao-Wei , Zhang Jian-Hua , Li Hong-Chao , Yang Zheng-Yan , Liu Zhong-Hua , Liu Guang-Chao , Ji Shao-Ping , Lu Feng
Published: April 2023

Supplementary Figure 1. Time-course analysis of the development of lung tumors induced by urethane in BALB/C mice and MS/MS analysis of destrin identified. Supplementary Figure 2. Validation of targeted proteins chosen by immunohistochemistry analysis. Supplementary Figure 3. Protein expression levels of Prdx5, Ctsd, Ctsh, Ctnna1, and Jup with reference to GAPDH (internal control), examined by immunoblot in the lung tissues of normal control mice and the mice at week 16 and 32 after Urethane treatment. Supplementary Figure 4. The effect of DSTN knockdown or overexpression on colony formation and migration in BEAS-2B cells. Supplementary Figure 5. Representative images of IHC staining using Ki67. Supplementary Figure 6. DSTN knockdown induces G2/M phase arrest in A549 and H1299 cells. Supplementary Figure 7. DSTN knockdown promotes apoptosis in A549 and H1299 cells. Supplementary Figure 8. The effect of DSTN knockdown or overexpression on the migration of A549 and H1299 in vitro. Supplementary figure 9. The effect of DSTN knockdown or overexpression on anchorage-independent growth of A549 and H1299 in vitro. Supplementary figure 10. The effect of DSTN knockdown or overexpression on EMT marker expression. Supplementary Figure 11. The effect of DSTN knockdown or overexpression on the adhesive ability of the A549 and H1299 cells. Supplementary Figure 12. DSTN knockdown or overexpression affects the sub-cellular localization of β-catenin in A549 and H1299 cells. Supplementary figure 13. The interaction between DSTN and β-catenin was assessed by Co-immunoprecipitation.
Table S2 from Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism
Authors: Dogra Samrita , Neelakantan Deepika , Patel Maulin M. , Griesel Beth , Olson Ann , Woo Sukyung
Published: April 2023

Antibody catalog numbers and dilutions used in western blots
Table S1 from Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism
Authors: Dogra Samrita , Neelakantan Deepika , Patel Maulin M. , Griesel Beth , Olson Ann , Woo Sukyung
Published: April 2023

Primer sequences for qRT-PCR
FigureS7 from Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism
Authors: Dogra Samrita , Neelakantan Deepika , Patel Maulin M. , Griesel Beth , Olson Ann , Woo Sukyung
Published: April 2023

CPT1a and AMPK activation downstream of APJ
Supplementary Fig. S1 from AXL Inhibition Induces DNA Damage and Replication Stress in Non–Small Cell Lung Cancer Cells and Promotes Sensitivity to ATR Inhibitors
Authors: Ramkumar Kavya , Stewart C. Allison , Cargill Kasey R. , Della Corte Carminia M. , Wang Qi , Shen Li , Diao Lixia , Cardnell Robert J. , Peng David H. , Rodriguez B. Leticia , Fan You-Hong , Heymach John V. , Wang Jing , Gay Carl M. , Gibbons Don L. , Byers Lauren A.
Published: April 2023

Supplementary Fig. S1: A subset of treatment-naïve NSCLC and LCNEC tumors expresses high AXL levels and EMT scores.
Supplementary Figure from Gene Body Methylation of the Lymphocyte-Specific Gene CARD11 Results in Its Overexpression and Regulates Cancer mTOR Signaling
Authors: McGuire Michael H. , Dasari Santosh K. , Yao Hui , Wen Yunfei , Mangala Lingegowda S. , Bayraktar Emine , Ma Wencai , Ivan Cristina , Shoshan Einav , Wu Sherry Y. , Jonasch Eric , Bar-Eli Menashe , Wang Jing , Baggerly Keith A. , Sood Anil K.
Published: April 2023

Supplementary Figure from Gene Body Methylation of the Lymphocyte-Specific Gene CARD11 Results in Its Overexpression and Regulates Cancer mTOR Signaling
Table S2 from IQ Motif-Containing GTPase-Activating Protein 2 Inhibits Breast Cancer Angiogenesis by Suppressing VEGFR2–AKT Signaling
Authors: Kumar Dinesh , Patel Saket Awadhesbhai , Khan Rehan , Chawla Saurabh , Mohapatra Nachiketa , Dixit Manjusha
Published: April 2023

List of antibodies
Figure S1 from IQ Motif-Containing GTPase-Activating Protein 2 Inhibits Breast Cancer Angiogenesis by Suppressing VEGFR2–AKT Signaling
Authors: Kumar Dinesh , Patel Saket Awadhesbhai , Khan Rehan , Chawla Saurabh , Mohapatra Nachiketa , Dixit Manjusha
Published: April 2023

Effect of IQGAP2 expression on angiogenic regulators.
Supplementary Data from Exosomal Delivery of FTO Confers Gefitinib Resistance to Recipient Cells through ABCC10 Regulation in an m6A-dependent Manner
Authors: Xiao Peng , Liu Yu-kang , Han Wei , Hu Yan , Zhang Bo-you , Liu Wen-liang
Published: April 2023

Clinical inclusion criteria, primer sequence and antibody information Supplemental Table 1. The specific primer and siRNAs sequences
Supplementary Table S1 from Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells
Authors: Bauzone Marjolaine , Souidi Mouloud , Dessein Anne-Frédérique , Wisztorski Maxence , Vincent Audrey , Gimeno Jean-Pascal , Monté Didier , Van Seuningen Isabelle , Gespach Christian , Huet Guillemette
Published: April 2023

Supplementary Table S1 displays the list of antibodies, siRNAs and primers used in the study
Supplementary Data from Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum
Authors: Penney Kathryn L. , Tyekucheva Svitlana , Rosenthal Jacob , El Fandy Habiba , Carelli Ryan , Borgstein Stephanie , Zadra Giorgia , Fanelli Giuseppe Nicolò , Stefanizzi Lavinia , Giunchi Francesca , Pomerantz Mark , Peisch Samuel , Coulson Hannah , Lis Rosina , Kibel Adam S. , Fiorentino Michelangelo , Umeton Renato , Loda Massimo
Published: April 2023

Supplementary figure legends Supplementary table 2
Supplemental Tables 1-5 from Genomic and Transcriptomic Correlates of Thyroid Carcinoma Evolution after BRAF Inhibitor Therapy
Authors: Lee Mark , Untch Brian R. , Xu Bin , Ghossein Ronald , Han Catherine , Kuo Fengshen , Valero Cristina , Nadeem Zaineb , Patel Neal , Makarov Vladimir , Dogan Snjezana , Wong Richard J. , Sherman Eric J. , Ho Alan L. , Chan Timothy A. , Fagin James A. , Morris Luc G.T.
Published: April 2023

Supplemental Table 1. Genomic alterations observed in MSK-THY1 Supplemental Table 2. Cellular prevalence of single nucleotide variants in MSK-THY Supplemental Table 3. Normalized gene expression data from patient MSK-THY1 Supplemental Table 4. Mutational data for 639 thyroid tumors sequenced by MSK-IMPACT Supplemental Table 5. Mutational data for BRAFi treated thyroid cancers with post-treatment sequencing
Supplementary Methods, Supplementary Tables 1-4. Sequences of shRNAs, primers and RT-qPCR assays from Functional Hierarchy and Cooperation of EMT Master Transcription Factors in Breast Cancer Metastasis
Authors: Addison Joseph B. , Voronkova Maria A. , Fugett James H. , Lin Chen-Chung , Linville Nathaniel C. , Trinh Brandon , Livengood Ryan H. , Smolkin Matthew B. , Schaller Michael D. , Ruppert J. Michael , Pugacheva Elena N. , Creighton Chad J. , Ivanov Alexey V.
Published: April 2023

Supplementary Table 1. Cloning primers Supplementary Table 2. shRNAs Supplementary Table 3. RT-qPCR primers Supplementary Table 4. MicroRNA RT-qPCR assays and microRNA mimics
Supplementary Figures 1-9 from Functional Hierarchy and Cooperation of EMT Master Transcription Factors in Breast Cancer Metastasis
Authors: Addison Joseph B. , Voronkova Maria A. , Fugett James H. , Lin Chen-Chung , Linville Nathaniel C. , Trinh Brandon , Livengood Ryan H. , Smolkin Matthew B. , Schaller Michael D. , Ruppert J. Michael , Pugacheva Elena N. , Creighton Chad J. , Ivanov Alexey V.
Published: April 2023

S1. The EMT-TFs bind similar E-box DNA consensus sequences. S2. Expression of ZEB1 and ZEB2 strongly correlates with the mesenchyma phenotype in breast cancer cell lines. S3. Low expression of miR200s/203/205 microRNAs strongly correlates with the mesenchymal phenotype in breast cancer cell lines. S4. Differential expression of EMT-TFs and epithelial-specific microRNAs in human breast cancer subtypes from the TCGA Breast dataset. S5. A. Higher expression of the majority of the 100 core epithelial genes in four intrinsic breast cancer subtypes compared to normal breast tissue. B. Expression of the mir34 family microRNAs is similar between basal and other breast cancer subtypes. S6. Correlation of expression of EMT-TFs with 100 core epithelial genes in four breast cancer subtypes and in normal breast tissue (labeled at the top of each graph) in the Breast TCGA dataset. S7. Fluorescence activated cell sorting (FACS) of CD24+/CD44- and CD24-/CD44+ subpopulations of HMLE cells. S8. Knockdown of ZEB1+ZEB2 in MDA231LN cells leads to characteristic change in expression of stemness markers. S9. Functional maps of Dox-inducible lentiviral expression vectors pLUT (A) and pTRIPZ (B).
Figure S3 from Qa-1b Modulates Resistance to Anti–PD-1 Immune Checkpoint Blockade in Tumors with Defects in Antigen Processing
Authors: Zhang Xiao , Sabio Erich , Krishna Chirag , Ma Xiaoxiao , Wang Jingming , Jiang Hui , Havel Jonathan J. , Chan Timothy A.
Published: April 2023

Figure S3. Flow cytometry of TILs of anti-PD-1 treated tumors.
Supplementary Table and Figures 1-3 from SOHLH2 Suppresses Angiogenesis by Downregulating HIF1α Expression in Breast Cancer
Authors: Cui Weiwei , Xiao Yunling , Zhang Ruihong , Zhao Na , Zhang Xianghong , Wang Fuwu , Liu Yang , Zhang Xiaoli , Hao Jing
Published: April 2023

Table S1: The correlation of sohlh2 expression and clinical characteristics. Figure S1. Sohlh2 suppresses HIF-1α-mediated proangiogenic factors in breast cancer cells. Figure S2. Sohlh2 exerted the inhibition on HIF-1α-mediated proangiogenic signaling pathway in xenografts. Figure S3. Mode: Sohlh2 inhibits breast cancer angiogenesis by tumor cell-mediated paracrine signaling pathway, downregulates HIF-1α transcription and suppresses breast cancer angiogenesis through HIF-1α-mediated proangiogenic axis.
Supplementary Data from R-Loop–Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin
Authors: Safari Maryam , Litman Thomas , Robey Robert W. , Aguilera Andrés , Chakraborty Arup R. , Reinhold William C. , Basseville Agnes , Petrukhin Lubov , Scotto Luigi , O'Connor Owen A. , Pommier Yves , Fojo Antonio T. , Bates Susan E.
Published: April 2023

Supplementary Figures 1-7 and Supplementary Table 1
Supplemental Figure 3 from Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor
Authors: Tyutyunyk-Massey Liliya , Sun Yilun , Dao Nga , Ngo Hannah , Dammalapati Mallika , Vaidyanathan Ashish , Singh Manjulata , Haqqani Syed , Haueis Joshua , Finnegan Ryan , Deng Xiaoyan , Kirberger Steve E. , Bos Paula D. , Bandyopadhyay Dipankar , Pomerantz William C.K. , Pommier Yves , Gewirtz David A. , Landry Joseph W.
Published: April 2023

Supplemental Figure 3. Validation of Autophagy by Microscopy and ATG5 KD in 4T1 Cells.
Supplemental Tables 1 and 2, Supplemental Figures 1-11 from Stromal-Derived Extracellular Vesicles Suppress Proliferation of Bone Metastatic Cancer Cells Mediated by ERK2
Authors: Shupp Alison B. , Neupane Manish , Agostini Lebaron C. , Ning Gang , Brody Jonathan R. , Bussard Karen M.
Published: April 2023

Supplemental Table 1. Antibodies used for immunofluorescence Supplemental Table 2. Antibodies used for western blotting Supplemental Figure 1: EO-MCF7 sEVs decrease MCF7 proliferation. Supplemental Figure 2: Primary EO sEVs regulate MDA-MB-231 S-phase entry. Supplemental Figure 3: EO sEVs suppress breast cancer cell proliferation more than other EO-derived soluble factors. Supplemental Figure 4: Paclitaxel does not induce pronounced DNA damage in MDA-MB-231 cells. Supplemental Figure 5: Primary EO sEVs protect MDA-MB-231 cells from doxorubicin-induced DNA damage. Supplemental Figure 6: Non-specific binding did not occur with antibodies in-vivo in bones injected with MDA-MB-231GFP/Luc2 breast cancer cells. Supplemental Figure 7: Non-specific binding did not occur with antibodies in-vivo in bones injected with MDA-MB-231GFP/Luc2 and MC3T3-E1 cells. Supplemental Figure 8: Non-specific binding did not occur with antibodies in-vivo in bones injected with MDA-MB-231GFP/Luc2 and EO-231 cells. Supplemental Figure 9: ERK2 is a key regulator of proliferation in MDA-MB-231 cells. Supplemental Figure 10: ERK2 regulates cellular sensitivity to chemotherapy-induced cell death. Supplemental Figure 11: miR-148a-3p regulates levels of p27 but not p21.
Figure S4 from mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
Authors: Haas Michael S. , Kagey Michael H. , Heath Heidi , Schuerpf Franziska , Rottman James B. , Newman Walter
Published: April 2023

DKK1 mRNA and Protein Expression Levels in Cell Culture Supernatant, Serum and Tumor
Figure S2 from mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
Authors: Haas Michael S. , Kagey Michael H. , Heath Heidi , Schuerpf Franziska , Rottman James B. , Newman Walter
Published: April 2023

Determination of Optimal mDKN-01 Dosing for a Melanoma B16F0 Model
Supplementary Methods from RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy
Authors: Bridges Allison E. , Ramachandran Sabarish , Tamizhmani Kavin , Parwal Utkarsh , Lester Adrienne , Rajpurohit Pragya , Morera Daley S. , Hasanali Sarrah L. , Arjunan Pachiappan , Jedeja Ravirajsinh N. , Patel Nikhil , Martin Pamela M. , Korkaya Hasan , Singh Nagendra , Manicassamy Santhakumar , Prasad Puttur D. , Lokeshwar Vinata B. , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: April 2023

Supplementary Methods
Supplementary Data from RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy
Authors: Bridges Allison E. , Ramachandran Sabarish , Tamizhmani Kavin , Parwal Utkarsh , Lester Adrienne , Rajpurohit Pragya , Morera Daley S. , Hasanali Sarrah L. , Arjunan Pachiappan , Jedeja Ravirajsinh N. , Patel Nikhil , Martin Pamela M. , Korkaya Hasan , Singh Nagendra , Manicassamy Santhakumar , Prasad Puttur D. , Lokeshwar Vinata B. , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: April 2023

Supplementary Figures and Legends 1-3
Supplementary Data, Supplementary Figures and Legends 1-13 from Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9
Authors: Itkonen Harri M. , Poulose Ninu , Steele Rebecca E. , Martin Sara E.S. , Levine Zebulon G. , Duveau Damien Y. , Carelli Ryan , Singh Reema , Urbanucci Alfonso , Loda Massimo , Thomas Craig J. , Mills Ian G. , Walker Suzanne
Published: April 2023

Supplementary figure 1. Validation of synthetic lethal interaction between OGT inhibition and AT7519 in LNCaP cells. Supplementary figure 2. Validation of synthetic lethal interaction between OSMI-2 and AT7519 in additional cell lines. Supplementary figure 3. Combination of OSMI-2 with AT7519 induces cells death in prostate cancer cells but not in cells derived from normal prostate epithelia. Supplementary figure 4. Characterization of RNA-seq data of cells treated with OGT inhibitor OSMI-2. Supplementary figure 5. OGT inhibition decreases phosphorylation of the carboxyterminal domain of RNA polymerase II. Supplementary figure 6. AT7519 enhances the effects of OGT inhibition by blocking the upregulation of OGT in PC3 cells. Supplementary figure 7. Summary of the RNA-seq data. Supplementary figure 8. Specific CDK9 inhibitor NVP2 is synthetically lethal in combination with OGT inhibition to LNCaP prostate cancer cells. Supplementary figure 9. OGT inhibition potentiates the anti-proliferative effects of CDK9 inhibitors Dinaciclib and SB1317 on prostate cancer cells. Supplementary figure 10. Knockdown of CDK9 sensitizes LNCaP prostate cancer cells to OGT inhibition. Supplementary figure 11. Combination of OSMI-2 with AT7519 further decreases the mRNA abundance of most mRNAs with half-life less than 4 hours. Supplementary figure 12. Determination of CDK9 inhibitor dose suitable for organoid experiments. Supplementary figure 13. Validation of synthetic lethality between inhibitors of OGT and CDK9 using models of castration-resistant prostate cancer (CRPC).
Supplementary Tables 1 and 2 from L-Plastin Promotes Gastric Cancer Growth and Metastasis in a Helicobacter pylori cagA-ERK-SP1–Dependent Manner
Authors: Teng Yong-Sheng , Chen Wan-Yan , Yan Zong-Bao , Lv Yi-Pin , Liu Yu-Gang , Mao Fang-Yuan , Zhao Yong-Liang , Peng Liu-Sheng , Cheng Ping , Duan Mu-Bing , Chen Weisan , Wang Yu , Luo Ping , Zou Quan-Ming , Chen Jun , Zhuang Yuan
Published: April 2023

Supplementary Table S1. The primers used for real-time PCR analysis Supplementary Table S2. ABPs obtained from Kyoto Encyclopedia of Genes and Genomes (KEGG) database
Supplementary Figures 1-6 from L-Plastin Promotes Gastric Cancer Growth and Metastasis in a Helicobacter pylori cagA-ERK-SP1–Dependent Manner
Authors: Teng Yong-Sheng , Chen Wan-Yan , Yan Zong-Bao , Lv Yi-Pin , Liu Yu-Gang , Mao Fang-Yuan , Zhao Yong-Liang , Peng Liu-Sheng , Cheng Ping , Duan Mu-Bing , Chen Weisan , Wang Yu , Luo Ping , Zou Quan-Ming , Chen Jun , Zhuang Yuan
Published: April 2023

S1. The GEPIA website (based on TCGA data) revealed that 48 ABPs were significantly up-regulated in GC tissues. S2. H. pylori induces L-plastin expression in GC cells. S3. Direct contact is required for H. pylori induced L-plastin expression in GC cells. S4. The vacA was not involved in the induction of L-plastin. S5. Decreased expression of L-plastin in presence of U0126 during H. pylori infection. S6. L-plastin expression is increased in GC tissues.
Supplementary Figures 1-6 from SLX4IP Promotes Telomere Maintenance in Androgen Receptor–Independent Castration-Resistant Prostate Cancer through ALT-like Telomeric PML Localization
Authors: Mangosh Tawna L. , Awadallah Wisam N. , Grabowska Magdalena M. , Taylor Derek J.
Published: April 2023

S1: Validation of TMM characterization techniques. S2: Expression of SLX4IP in mCRPC versus primary disease. S3: SLX4IP knockdown correlates with accelerated telomere shortening. S4: SLX4IP knockdown is accompanied by a blunted atypical ALT phenotype. S5: SLX4IP knockdown promotes telomere shortening and senescence. S6: Androgen-independent marker expression and telomere length changes following androgen deprivation.
Supplementary Data from circ_0041732 Promotes Breast Cancer Progression
Authors: Ye Guolin , He Suqun , Pan Ruilin , Zhu Lewei , Zhou Dan , Cai Genxi , Chen Peixian
Published: April 2023

Supplementary Data from circ_0041732 Promotes Breast Cancer Progression
Supplementary Figures 1-4 from Subtype and Site Specific–Induced Metabolic Vulnerabilities in Prostate Cancer
Authors: Mossa Federica , Robesti Daniele , Sumankalai Ramachandran , Corey Eva , Titus Mark , Kang Yuqi , Zhang Jianhua , Briganti Alberto , Montorsi Francesco , Vellano Christopher P. , Marszalek Joseph R. , Frigo Daniel E. , Logothetis Christopher J. , Gujral Taranjit S. , Dondossola Eleonora
Published: April 2023

S1. Seahorse assays on C4-2B and PC3 cells cultured in 2D.
S2. Seahorse assays on C4-2B and PC3 cells cultured in 2D and treated with IACS-10759.
S3. Luciferase assay and crystal violet staining are comparable methods for monitoring PCa cells growth.
S4. Representative pictures of tumor-free, PC3 tumor-bearing control and PC3 tumor-bearing IACS-10759 treated tibiae.
Supplementary Figure from Cytokeratins 5 and 17 Maintain an Aggressive Epithelial State in Basal-Like Breast Cancer
Authors: McGinn Olivia , Riley Duncan , Finlay-Schultz Jessica , Paul Kiran V. , Kabos Peter , Sartorius Carol A.
Published: April 2023

Supplementary Figure from Cytokeratins 5 and 17 Maintain an Aggressive Epithelial State in Basal-Like Breast Cancer
Supplementary Figures and Tables from ATF6-Mediated Signaling Contributes to PARP Inhibitor Resistance in Ovarian Cancer
Authors: McMellen Alexandra , Yamamoto Tomomi M. , Qamar Lubna , Sanders Brooke E. , Nguyen Lily L. , Ortiz Chavez Daniela , Bapat Jaidev , Berning Amber , Post Miriam D. , Johnson Joshua , Behbakht Kian , Nurmemmedov Elmar , Chuong Edward B. , Bitler Benjamin G.
Published: April 2023

Table S1 - Antibody Details
Table S2 - Primer Sequences
Table S3 - AP1 shRNA Screen Details
Table S4 - Patient Characteristics from Tissue Microarray
Table S5 - Transcription factor overlap
Figure S1 - Dose response, AP1 activity and AP1 subunit expression.
Figure S2 - ATF6 Immunohistochemistry, KM Curve, and AP1 transcriptional targets
Figure S3 - P38 Inhibitor Dose Response
Figure S4 - DNA Damage in OVCA420 cell line and qPCR expression of BRCA1 and PARP1
Figure S5 - Controls for animal study
Supplementary Figure from Suppression of SIN3A by miR-183 Promotes Breast Cancer Metastasis
Authors: Davenport Mackenzie L. , Davis Mara R. , Davenport Baylea N. , Crossman David K. , Hall Aaron , Pike Jason , Harada Shuko , Hurst Douglas R. , Edmonds Mick D.
Published: April 2023

Supplementary Figure from Suppression of SIN3A by miR-183 Promotes Breast Cancer Metastasis
Supplementary Tables 1-5, Supplementary Figures 1-3 from Transcriptomes of Prostate Cancer with TMPRSS2:ERG and Other ETS Fusions
Authors: Stopsack Konrad H. , Su Xiaofeng A. , Vaselkiv J. Bailey , Graff Rebecca E. , Ebot Ericka M. , Pettersson Andreas , Lis Rosina T. , Fiorentino Michelangelo , Loda Massimo , Penney Kathryn L. , Lotan Tamara L. , Mucci Lorelei A.
Published: April 2023

Table S1. ETS genes with weaker evidence for association with ERG fusion status.
Table S2. Androgen receptor transcriptional activity, measured as a más-o-menos score of the Hiernonymus et al. (2006) signature and expressed in standard deviations within a cohort, between ETS-defined subtypes, in TCGA and the Hopkins cohort.
Table S3. All genes associated with ERG vs. non-ERG status among the Berglund et al. ETS genes, sorted by increasing p-value in HPFS/PHS. Missing estimates for the validation cohorts (HPFS/PHS and Hopkins) indicate the gene was not measured on the microarrays used in these studies.
Table S4. Ratios between Black and White men for ratios of expression between ETS vs. non-ETS tumors.
Table S5. Gene set analysis for Hallmark gene sets associated with ERG vs. non-ERG (top), ETS vs. non-ETS (middle), and non-ERG ETS vs. non-ETS status (bottom).
Figure S1. Gene expression ratios in TCGA for ETS vs. non-SPOP non-ETS (x axis) and ETS vs. SPOP non-ETS (y-axis). One dot is one tumor.
Figure S2. Androgen receptor transcriptional activity by subtype. One dot is one tumor.
Figure S3. ETS-related AR target genes.
Supplementary Figure S6 from Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype
Authors: Voigt Ellen , Wallenburg Madeline , Wollenzien Hannah , Thompson Ethan , Kumar Kirtana , Feiner Joshua , McNally Moira , Friesen Hunter , Mukherjee Malini , Afeworki Yohannes , Kareta Michael S.
Published: April 2023

SOX2 expression by subtype and cell line
Supplementary Figure S5 from Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype
Authors: Voigt Ellen , Wallenburg Madeline , Wollenzien Hannah , Thompson Ethan , Kumar Kirtana , Feiner Joshua , McNally Moira , Friesen Hunter , Mukherjee Malini , Afeworki Yohannes , Kareta Michael S.
Published: April 2023

WGCNA network identification
Supplementary Data from Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma
Authors: Schoenfeld David A. , Zhou Royce , Zairis Sakellarios , Su William , Steinbach Nicole , Mathur Deepti , Bansal Ankita , Zachem Alexis L. , Tavarez Bertilia , Hasson Dan , Bernstein Emily , Rabadan Raul , Parsons Ramon
Published: April 2023

Supplementary Data from Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma
Supplementary Table 1 from GATM-Mediated Creatine Biosynthesis Enables Maintenance of FLT3-ITD–Mutant Acute Myeloid Leukemia
Authors: Zhang Yuan , Newsom Kimberly J. , Zhang Mei , Kelley Jeffry S. , Starostik Petr
Published: April 2023

Primers used in the study
Supplementary Data from Targeted Rejuvenation of Exhausted Chimeric Antigen Receptor T Cells Regresses Refractory Solid Tumors
Authors: Luo Qian , Napoleon John V. , Liu Xin , Zhang Boning , Zheng Suilan , Low Philip S.
Published: April 2023

Supplementary Data from Targeted Rejuvenation of Exhausted Chimeric Antigen Receptor T Cells Regresses Refractory Solid Tumors
Table S2 from Hypertension Promotes the Proliferation and Migration of ccRCC Cells by Downregulation of TIMP3 in Tumor Endothelial Cells through the miR-21–5p/TGFBR2/P38/EGR1 Axis
Authors: Wang Chenguang , Xu Haibo , Liao Xinhui , Wang Weiming , Wu Wanjun , Li Wujiao , Niu Liman , Li Zhichao , Li Aolin , Sun Yangyang , Huang Weiren , Song Fei
Published: April 2023

Primers for RT-PCR
Supplementary Figure from Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4
Authors: Mittal Karuna , Kaur Jaspreet , Sharma Shaligram , Sharma Nivya , Wei Guanhao , Choudhary Ishita , Imhansi-Jacob Precious , Maganti Nagini , Pawar Shrikant , Rida Padmashree , Toss Michael S. , Aleskandarany Mohammed , Janssen Emiel A. , Søiland Håvard , Gupta Meenakshi. V. , Reid Michelle D. , Rakha Emad A. , Aneja Ritu
Published: April 2023

Supplementary Figure from Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4
Supplementary Figure from Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing Vaptans
Authors: Heidman Laine M. , Peinetti Nahuel , Copello Valeria A. , Burnstein Kerry L.
Published: April 2023

Supplementary Figure from Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing Vaptans
Supplementary Data from Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing
Authors: Pham Minh-Tam , Gupta Anuj , Gupta Harshath , Vaghasia Ajay , Skaist Alyza , Garrison McKinzie A. , Coulter Jonathan B. , Haffner Michael C. , Zheng S. Lilly , Xu Jianfeng , DeStefano Shields Christina , Isaacs William B. , Wheelan Sarah J. , Nelson William G. , Yegnasubramanian Srinivasan
Published: April 2023

Supplementary Data from Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing
Supplementary Figure 4 from DCLK1-Short Splice Variant Promotes Esophageal Squamous Cell Carcinoma Progression via the MAPK/ERK/MMP2 Pathway
Authors: Ge Yang , Fan Xiaona , Huang Xuying , Weygant Nathaniel , Xiao Zeru , Yan Rui , Liu Heshu , Liu Jian , An Guangyu , Yao Jiannan
Published: April 2023

Figure S4 shows inhibition of DCLK1-S with LRRK2-IN-1 decreased the malignant phenotype of ESCC cells.
Supplementary Table 2 from Improved Delineation of Colorectal Cancer Molecular Subtypes and Functional Profiles with a 62-Gene Panel
Authors: Bhukdee Dhup , Nuwongsri Pattarin , Israsena Nipan , Sriswasdi Sira
Published: April 2023

Expression levels of panel genes, subtypes, 2D visualization coordinates, and mutation info for each sample
Supplementary Table 1 from Improved Delineation of Colorectal Cancer Molecular Subtypes and Functional Profiles with a 62-Gene Panel
Authors: Bhukdee Dhup , Nuwongsri Pattarin , Israsena Nipan , Sriswasdi Sira
Published: April 2023

List of 62 genes of our proposed panel
Figure S7 from The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Authors: Schieven Sebastiaan M. , Traets Joleen J.H. , Vliet Alex v. , Baalen Martijn v. , Song Ji-Ying , Guimaraes Marcos Da Silva , Kuilman Thomas , Peeper Daniel S.
Published: April 2023

Modulation of AXL neither affects cell proliferation nor sensitivity to MEK inhibition.
Figure S4 from The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Authors: Schieven Sebastiaan M. , Traets Joleen J.H. , Vliet Alex v. , Baalen Martijn v. , Song Ji-Ying , Guimaraes Marcos Da Silva , Kuilman Thomas , Peeper Daniel S.
Published: April 2023

Extended data on Figure 4: Elongin B/C interact with AXL and loss of Elongin B/C stabilizes AXL protein levels.
Figure S3 from The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Authors: Schieven Sebastiaan M. , Traets Joleen J.H. , Vliet Alex v. , Baalen Martijn v. , Song Ji-Ying , Guimaraes Marcos Da Silva , Kuilman Thomas , Peeper Daniel S.
Published: April 2023

Extended data on Figure 3: Elongin B/C regulate AXL independently of hypoxia.
Figure S2 from The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Authors: Schieven Sebastiaan M. , Traets Joleen J.H. , Vliet Alex v. , Baalen Martijn v. , Song Ji-Ying , Guimaraes Marcos Da Silva , Kuilman Thomas , Peeper Daniel S.
Published: April 2023

Extended data on Figure 2: Elongin BC complex members serve as keyAXL regulators.
Figure S3 from TBX3 Promotes Cervical Cancer Proliferation and Migration via HPV E6 and E7 Signaling
Authors: Khan Saif F. , Burmeister Carly A. , Scott David J. , Sinkala Musalula , Ramburan Amsha , Wu Hue-Tsi , Schäfer Georgia , Katz Arieh A. , Prince Sharon
Published: April 2023

FLAG-TBX3 overexpression in C33A, C33A HPV18 E6/7, CaSki and HeLa cells confirmed by western blotting.