bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimating long-term overall survival with olaparib as maintenance therapy in patients with newly diagnosed advanced ovarian cancer with BRCA mutations
Authors: Avxentyev N. A. , Khokhlova S. V. , Frolov M. Yu. , Makarov A. S.
Published: October 2021

Background. According to randomized clinical trial SOLO1 olaparib statistically significantly improves progression-free survival versus placebo as a maintenance monotherapy in patients aged 18 and over with newly diagnosed advanced ovarian cancer with BRCA mutations, who had response to first-line chemotherapy. As the data on overall survival (OS) in this trial remains interim it is still uncertain whether treatment with olaparib can provide any benefits in terms of OS.

Objective: to evaluate a long-term OS for olaparib versus placebo as a maintenance monotherapy in patients with newly diagnosed advanced ovarian cancer with BRCA mutations, who had response to first-line chemotherapy.

Materials and methods. A 10-year mathematic model of disease progression and survival on olaparib versus placebo was developed. Modelling was based on data on progression-free survival from SOLO1 trial and data on OS after platinum-sensitive and platinum-resistant relapses from OCEANS and AURELIA trials. Additionally, patients who haven’t been treated with olaparib after first-line therapy in base-case scenario were assumed to get olaparib as a second-line treatment after platinum-sensitive relapse; mortality modelling for these patients was based on data from SOLO2 trial.

Results. Median OS for olaparib was 107 months versus 66 months for placebo. 46 % of patients treated with olaparib were alive by the end of 10-year modelling period, but only 28 % patients from the placebo group. Hazard ratio of death for olaparib versus placebo was 0.64 (95 % confidence interval 0.49–0.84). Probabilistic sensitivity analysis showed robustness of these results.

Conclusion. Using olaparib as a maintenance therapy in patients with newly diagnosed advanced ovarian cancer with BRCA mutations, who had response on first line chemotherapy, statistically significantly reduces risk of death by 36 %, compared to placebo.
Influence of physical rehabilitation on oxygen and lactate status in "inotrope-dependent" patients with chronic heart failure in class III–IV
Authors: Bortsova Maria A. , Demchenko Elena A. , Bautin Andrey E. , Fedotov Petr A. , Marichev Aleksandr O. , Fedorova Maria A. , Korneva Lubov O. , Sitnikova Maria Y.
Published: October 2021

Aim. To assess the effect of physical rehabilitation on dynamics of oxygen and lactate status indicators in inotrope-dependent patients with stable chronic heart failure (CHF) of IIIIV functional class (FC).
Material and methods. A randomized prospective study included 120 men, aged 1865, hospitalized at Almazov National Medical Research Centre due to CHF IIIIV FC, left ventricular ejection fraction (LVEF) 30%; with blood pressure (BP)90/60 mm Hg. Patients who received dobutamine or dopamine for 2 weeks were randomized into 3 groups: 1st participating in the program of physical training (PPT), 2nd not participating; 3rd group patients without inotropic support participating in PPT.
Results. Oxygen extraction ratio (O2ER) at rest was increased, while central venous oxygen saturation (ScvO2) was decreased in all groups at baseline, after 3 and 6 months. Initially, at rest, central venous blood lactate (lactate) was normal in all groups. By the 6th month, lactate in group 2 became higher than in group 1 (p=0.005) and group 3 (p=0.008). Initially, after 3 and 6 months, at peak of exercise in groups 1 and 3, lactate and O2ER increased, and ScvO2 decreased without development of life-threatening adverse events. By the 6th month, in groups 1 and 3, the distance of 6-minute walk test increased: p=0.004 and p0.00001 and the strength of hand muscles increased: p=0.01 and p=0.005.
Conclusion. In patients with CHF IIIIV FC at rest, regardless of participation in PPT and inotropic therapy, there were comparable disturbances of oxygen status, characterized by decreased level of ScvO2 and increased level of O2ER, in the absence of decrease in arterial blood saturation. At peak of aerobic exercise of mild and moderate intensity in patients with advanced CHF, regardless of inotropic support, there was a comparable increase in the level of lactate and O2ER, as well as a decrease in ScvO2, which was not accompanied by life-threatening adverse events. The participation of inotrope-dependent patients in PPT is associated with decrease in blood lactate at rest, which, along with increase in hand muscle strength and exercise tolerance, may indicate an improvement in condition of muscle tissue.
Main trends and regularities of the formation of disability due to ischemic heart disease in Russia in 2006–2017
Authors: Chandirli Sevda A. , Puzin Sergey N.
Published: October 2021

The article analyzes features and structure of disability due to coronary heart disease in Russia and identifies the main trends and patterns of the formation of primary, secondary and general disability over a long period (20062017). New scientific data has been obtained on the structure of disability by age and severity.
Antithrombotic therapy and its impact on prognosis in patients with atrial fibrillation and myocardial infarction. Long-term observation results
Authors: Soloveva Mariia V. , Boldueva Svetlana A.
Published: October 2021

Aim. To study antithrombotic therapy (ATT) in patients with myocardial infarction (MI) type 1 and preexisting atrial fibrillation (AF), effect of ATT on prognosis.
Material and methods. 100 patients with type 1 MI and preexisting AF were selected. The exclusion criterion was severe concomitant pathology.
Results. Only 13.0% of AF patients took anticoagulants (AC) adequately before hospitalization. 94.0% of patients in hospital and 80.5% at discharge were prescribed triple ATT at least for 1 month with transition to dual ATT (AC + disaggregant) for 12 months. ACs were prescribed in hospital in 100.0% of cases, at discharge in 93.1%. After 1 year 8.4% of patients stopped taking ACs, after 2.31.9 years 15.7%. The incidence of ischemic and hemorrhagic events didnt differ in patients with different regimens of ATT (double/triple) and types of AСs (vitamin K antagonists/non-vitamin K antagonist ACs). In the long-term period patients, who took ACs incorrectly or stopped taking ACs, had increased risks of stroke (OR 9.580; 95% CI 1.15379.599, p=0.0365); combined endpoint: recurrent MI + stroke + cardiovascular mortality (OR 2.556; 95% CI 1.1045.918, p=0.0284).
Сonclusion. Patients with preexisting AF had a low adherence to ACs prior to MI. It increased after hospitalization and decreased during follow-up. In the long-term period patients, who took ACs incorrectly or stopped taking ACs, had significantly increased risks of stroke, combined endpoint. There were no differences in the prognosis depending on the type of ACs, the regimens of ATT administered in accordance with ischemic and hemorrhagic risks.
Formation of legislation on pension insurance in France, Great Britain, and Russia. A retrospective
Authors: Aleksandrova Anna V. , Lapaeva Angelina V. , Ryzhova Anastasia A. , Serebryakova Elena A.
Published: October 2021

The relevance of the study is due to the crisis of modern pension insurance systems and the need to change the paradigm of pension legislation development. The purpose of the study is to identify the features of the formation of legislation on pension insurance in several countries (France, Great Britain, and Russia) at the initial stage of development (before 1914). The novelty is expressed both in the formulation of the problem and in the research methodology (the choice of countries and the period of research, the justification for the use of methods: dialectics, analysis, synthesis, system-structural, sociological, statistical, historical-legal, comparative-legal, formal-legal). The result of the study was the conclusions about the historical conditionality of the peculiarities of the formation of legislation on pension insurance in a particular country. There was early legalization of both voluntary and compulsory pension insurance in France. There was no legislation on pension insurance in the UK during the period under review, despite the early development of relevant institutions in the framework of workshops, guilds, and later in the framework of trade unions and “friendly societies”. In Russia, due to the agrarian nature of the economy, pension insurance did not develop within the framework of workshops and guilds; there were no laws on insurance in case of old age by 1914, while the risks of disability and loss of the breadwinner were regulated by law.
Integrated Reasoning Engine for Code Clone Detection
Authors: Bynagari Naresh Babu
Published: October 2021

This article seeks to foray into the nitty-gritty of integrated reasoning for code clone detection and how it is effectively carried out, given the amount of analytics usually associated with such activities. Detection of codes requires high-pitch familiarity with cloning systems and their workings. Hence, discovering similar code segments that are often regarded and seen as code imitations (clone) is not an easy responsibility. More especially, this very detection process might possess key purposes in the context of susceptibility findings, refactoring, and imitation detecting. Through the voyage of discovery this article intends to expose you to, you will realize that identical code segments, more often than not described as code clones, appear to be a serious duty, especially for large code bases <1; 2; 3; 4>. There are certain approaches and deep technicalities that this sort of detection is known for. Still, from the avalanche of resources that formed the bedrock of this article, one would discover the easiest formula to adopt in maneuvering such strenuous issues.
Gradient Descent is a Technique for Learning to Learn
Authors: Neogy Taposh Kumar , Bynagari Naresh Babu
Published: October 2021

In machine learning, the transition from hand-designed features to learned features has been a huge success. Regardless, optimization methods are still created by hand. In this study, we illustrate how an optimization method's design can be recast as a learning problem, allowing the algorithm to automatically learn to exploit structure in the problems of interest. On the tasks for which they are taught, our learning algorithms, implemented by LSTMs, beat generic, hand-designed competitors, and they also adapt well to other challenges with comparable structure. We show this on a variety of tasks, including simple convex problems, neural network training, and visual styling with neural art.
Theoretical Approaches of Machine Learning to Schizophrenia
Authors: Bynagari Naresh Babu , Fadziso Takudzwa
Published: October 2021

Machine learning techniques have been successfully used to analyze neuroimaging data in the context of disease diagnosis in recent years. In this study, we present an overview of contemporary support vector machine-based methods developed and used in psychiatric neuroimaging for schizophrenia research. We focus in particular on our group's algorithms, which have been used to categorize schizophrenia patients and healthy controls, and compare their accuracy findings to those of other recently published studies. First, we'll go over some basic pattern recognition and machine learning terms. Then, for each study, we describe and discuss it independently, emphasizing the key characteristics that distinguish each approach. Finally, conclusions are reached as a result of comparing the data obtained using the various methodologies presented to determine how beneficial automatic categorization systems are in understanding the molecular underpinnings of schizophrenia. The primary implications of applying these approaches in clinical practice are then discussed.
ЭКОНОМИКА И ГЕОПОЛИТИКА «МОРСКОГО ШЕЛКОВОГО ПУТИ»*
Authors: Козьменко С.
Published: October 2021

В статье исследованы возможности и перспективы обеспечения безопасности морских коммуникаций при надежном пополнении запасов нефти и газа как основы развития экономики Китая. При этом показана ограниченная роль России в экспорте энергетических ресурсов в Китай. Выявлены возможные вызовы и угрозы по линии соприкосновения интересов Китая и США и показано значение российско-китайского взаимодействия при позиционировании обеих стран на геополитическом атласе современного мира. В статье подтверждается значение стратегических ядерных сил и в целом политики ядерного сдерживания в системе международных отношений. Обоснованы направления взаимодействия России и Китая в рамках проекта «Морского Шелкового пути XXI века» и развития пространства учений «Морское взаимодействие» в Арктике
Rapid review of clinical reunification intervention to families
Authors: Mathebula Shongile , Malan Hanelie , Mmusi Fatima
Published: October 2021

Purpose of the study: The aim of this paper is to examine literature on the clinical content of reunification interventions social workers render to families. Methodology: A rapid review of the literature was carried out. Electronic databases, such as eBook Collection (EBSCOhost), PsycARTICLES, PsycINFO, SocINDEX with Full Text, Academic Search Premier, CINAHL with Full Text, and JSTOR Journals, were explored by making use of specific keywords. A quality appraisal was done using the CASP (2018), the AACODS checklist, and the EPHPP (2009) to appraise the quantitative studies. Eleven articles were synthesised using thematic analysis. Main Findings: The review indicates that the exact nature of the clinical content of reunification intervention rendered to families is not clear, although empirical evidence suggests that the clinical content of reunification intervention rendered to families comprises of engagement, parental visiting and contact, parenting capacity building, and support groups. In addition, supporting birth parents with concrete resources like transportation and stable housing can be identified as an extra intervention that may support successful reunification. Applications of this study: This study has the potential to contribute to the child welfare system by enhancing the need for programmes and policies that focus on addressing the clinical characteristics of family reunification interventions. Recommendations were made that can provide guidance and insight on the important aspects that should form part of reunification services to meet the emotional and psychological needs of the children and their birth families. Novelty/Originality of this study: The outcome of the study has provided insight into components that are regarded to be of importance and should form part of the clinical content of reunification services rendered to families.
Dyskusja
Authors: Dopierała Renata , Waniek Katarzyna
Published: October 2021

Rozmowa dotyczy zasadności wznowienia publikacji "Biografia a tożsamość narodowa". Jej pierwsze wydanie ukazało się w 1996 roku (drugie w 1997) i zastosowano w niej autobiograficzny wywiad narracyjny, pionierską wówczas formę, która do dziś budzi nieustające zainteresowanie badaczy.
Wywiad narracyjny – technika i pojęcia analityczne
Authors: Kaźmierska Kaja
Published: October 2021

Autorka omawiając metodę wywiadu narracyjnego autorstwa Fritza Schützego skoncentruje się przede wszystkim na opisie samej techniki oraz po pierwsze, na tych tezach teoretycznych, które uzasadniają ideę zbierania tego rodzaju materiałów, po drugie zaś zostały wykorzystane przez autorów poszczególnych opracowań. Podsumowując, celem Autorki jest jedynie opis wybranych aspektów omawianej metody.
Obrazy innych etnicznych a tożsamość narodowa
Authors: Bokszański Zbigniew
Published: October 2021

Artykuł składa się z dwóch części. W pierwszej z nich Autor prezentuje założenia projektu badań nad obrazami innych narodowości. Na mocy tych założeń obrazy innych grup etnicznych rozpatruje w powiązaniu z tożsamością grupy, której członkowie prezentowali właściwe im sposoby postrzegania „innych etnicznych”. Podejście to wykracza poza tę tradycję badawczą i ten punkt widzenia, które ukształtowały się wokół koncepcji stereotypu, skłaniającej do rozpatrywania percepcji „innych etnicznych” jako fenomenu „psychologicznego” raczej oddzielonego od ogólnych właściwości kultury osób konstruujących obrazy innych. W części drugiej Autor przedstawia rezultaty badania wraz z ogólniejszymi konkluzjami odnoszącymi się do miejsca reguł budowania obrazów niektórych „innych etnicznych” w tożsamości narodowej Polaków.
Doświadczenia wojenne Polaków – analiza trajektorii wrześniowej
Authors: Rokuszewska-Pawełek Alicja
Published: October 2021

Celem analizy przeprowadzanej przez Autorkę jest charakterystyka utrwalonego w pamięci obrazu trajektorii wojennej Polaków w ich możliwych, zróżnicowanych wariantach.
Konstruowanie narracji o doświadczeniu wojennej biografii. Na przykładzie analizy narracji kresowych
Authors: Kaźmierska Kaja
Published: October 2021

Autorka w swojej pracy analizuje narracje kresowe okresu II wojny światowej, zaś historie osób, które przeżyły wojnę w Polsce centralnej, stanowią jedynie tło, punkt odniesienia, pozwalający ustalić specyfikę narracji kresowych. Do podjęcia tematu od tej strony skłoniło Autorkę przekonanie, że obraz wojny oraz "typowa" wojenna biografia osób z Polski centralnej są mocno ugruntowane w pamięci zbiorowej, w przeciwieństwie do narracji kresowych.
Pozytywne doświadczenia biograficzne w kontekście okupacji: oportunizm i opór
Authors: Marciniak Mieczysław
Published: October 2021

Kwestia „pozytywnego doświadczenia” w kontekście wojny i okupacji może prowadzić do niepotrzebnych w punkcie wyjścia kontrowersji. Aby ich uniknąć, Autor na wstępie jasno określa, do jakich faktów i jakich problemów ogranicza swoje opracowanie. Wyjściowym faktem jest, że w zbiorze narracji dotyczących okresu wojny i okupacji, pochodzących z badań „Biografia a tożsamość narodowa”, nieliczni narratorzy wprost formułują pozytywne oceny mieszczące się w spektrum od „żyło mi się całkiem dobrze” po „to była przygoda”. Fakt ten prowadzi do trzech pytań problemowych: 1) w jakich wymiarach dokonywana jest pozytywna ocena własnych doświadczeń biograficznych, 2) w jakich warunkach mogą się pojawić pozytywnie oceniane doświadczenia biograficzne w czasie okupacji, 3) jakie konsekwencje dla interpretacji cierpienia i śmierci innych (spowodowanych wojną i okupacją) ma „pozytywna” interpretacja własnego doświadczenia. W opracowaniu Autor wykorzystał zasady metody opracowanej przez Fritza Schützego. Jest zrozumiałe, że osiągnięcie poziomu ugruntowanych twierdzeń teoretycznych jest zadaniem bardzo pracochłonnym i przez to odległym. W niniejszym tekście Autor ogranicza się do analizy czterech przypadków reprezentujących dwa różne środowiska społeczne i zarazem dwa różne i przeciwstawne wymiary „pozytywnych” doświadczeń okupacyjnych.
Doświadczenia wojenne Polaków – analiza trajektorii okupacyjnych
Authors: Rokuszewska-Pawełek Alicja
Published: October 2021

Autorka w swojej pracy omawia strukturalne, ramowe warunki trajektorii kolektywnej, które w przypadku doświadczeń wrześniowych związane były z kolektywnym chaosem, dezorganizacją i bezładem, w przypadku doświadczeń okupacyjnych wiążą się z zewnętrznym przymusem: z jednej strony – ze skrajnymi ograniczeniami dnia codziennego, materialną nędzą, koniecznością podejmowania niekorzystnych dla siebie działań, przymusem pracy, często na niewolniczych warunkach, z drugiej zaś – z formami przymusu związanymi z okupacyjnym terrorem, z aresztowaniami i uwięzieniami, deportacjami, osadzeniem w obozach pracy i obozach zagłady, ukrywaniem się.
Pasja i folklor pamięci
Authors: Marciniak Mieczysław
Published: October 2021

Autor przedstawia swoją propozycję rozumienia pasji (cierpienia), która jest konstrukcją typu idealnego służącego wyznaczeniu pewnego wymiaru, w jakim mogą lokować się empiryczne narracje autobiograficzne, to znaczy między pasją a folklorem. Na mocy założenia konstrukcyjnego większość empirycznie danych narracji lokuje się w pobliżu bieguna folkloru, zarazem cała konstrukcja byłaby chybiona, gdyby nie można było podać przypadku leżącego blisko bieguna pasji.
Presja i wina: wojenne doświadczenia młodego żołnierza niemieckiego i ich biograficzne implikacje
Authors: Schütze Fritz
Published: October 2021

W szeroko dyskutowanej pracy psychoanalitycy Margarete i Alexander Mitscherlichowie postawili tezę, że Niemcy nie byli w sanie odczuwać żalu i skruchy z powodu tragedii jaką była II wojna światowa – milionów pochłoniętych ludzkich istnień i cierpień ofiar nazistowskiego terroru. Utrzymywali, że Niemcy tłumili bądź zaprzeczali temu, co się wydarzyło, aby móc uniknąć udręk wywołanych głęboką depresją. W poniższym studium poddam krytyce ową hipotezę Mitscherlichów pokazując szeroki wachlarz możliwych indywidualnych uwikłań (zwanego „trajektorią”) w autobiograficznie zróżnicowane doświadczenia związane z życiem w świecie całkowitego kolektywnego upadku moralnego. Niezbędne badania mające na celu potwierdzenie lub obalenie wspomnianej hipotezy zostały przeprowadzone z zastosowaniem metody „autobiograficznego wywiadu narracyjnego” stworzonej przez autora. Ten, oparty na drobiazgowej analizie strukturalnej, rodzaj badania został rozwinięty przy użyciu formalnych wskaźników tekstowych pozwalających na identyfikację takich zjawisk jak przesłonięcie, opóźnione wspomnienia, rozproszone („compartmentalized”) etapy przepracowywania. Charakterystyczne dla tej metody jest to, że dane wyłaniają się z analizy pierwszego przypadku — tutaj jest nim ideologicznie niezaangażowany Niemiec. W czasie II wojny światowej będąc młodym niemieckim żołnierzem również i on przechodził przez okresy niezdolności do odczuwania żalu i skruchy. Jednak informant w tym stanie nie pozostał. Doświadczenie poważnego kryzysu w jego życiu osobistym doprowadziło do nagłego przypomnienia sobie spotkania ofiar nazistowskiego terroru. Zaczął odczuwać żal i skruchę. Poza empirycznym dowodem na to, że poczucie osobistego uwikłania w zbiorową winę towarzyszyło również osobom niezaangażowanym w intencjonalne akty niemoralnych działań, mamy tu też do czynienia z intrygującym zjawiskiem opóźnionego odczuwania żalu i skruchy wynikającym z moralnego upadku wspólnoty „My, Niemcy”. Wniosek ten został potwierdzony w danych z wielu wywiadów narracyjnych z innymi Niemcami, którzy także nie byli zaangażowani w nazistowską ideologię, ale brali aktywy udział w działaniach niemieckiej machinerii wojennej.
Eco-friendly Approach for the Management of Rust Red Flour Beetle, Tribolium castaneum (Herbst) on Wheat Grains
Authors: Sekar Gulappa Chandra , Singh Kh. Ibohal , Loganathan R. , Singh Okendro
Published: October 2021

Background: Wheat is the major cereal crop occupying an eminent place in economy of our country. About 10-15% wheat is lost annually due to ravages of stored grains pests during storage. The principal stored grain pest of wheat is red flour beetle Tribolium castaneum (Herbst) which is a cosmopolitan and most serious pest. Methods: The present investigation was carried out in the Entomology Laboratory during 2020-2021, College of Agriculture, Central Agricultural University, Imphal to investigate eco-friendly management of rust red flour beetle, Tribolium castaneum on wheat grains by using different inert materials viz., paddy straw, paddy husk ash, cow dung ash, coal ash, sand dust, saw dust, boric acid and one untreated control with the dose of 1.5 gm/100 gm of wheat grains. Result: The results showed that the boric acid exhibited 100 per cent adult mortality of T. castaneum within 5 days after treatment. Afterwards the next best treatment was cow dung ash, coal ash shows the very effective in treatment in the adult emergence and grain weight loss. Whereas, saw dust shows the least effective treatment in the controlling adult emergence.
Spices Production in Ethiopia: A Review
Authors: Deribe Habtamu
Published: October 2021

These papers describe spices production in Ethiopia. There are different Spices and herbs can be categorized based on their flavor and colour i.e., hot (Cayenne pepper, black and white peppers, mustard, chilies) slight flavor (coriander, paprika), aromatic spices (clove, cumin, dill fennel, nutmeg, mace, cinnamon) and aromatic herbs (thyme, marjoram, shallot, basil, bay leaf, onion, garlic). Based on colour (turmeric) and herbaceous (sage, rosemary) or based on their taste such as sweet, bitter, spicy, sour and sharp. Therefore, in Ethiopia Korarima, fenugreek, ginger, long pepper, vanilla, capsicum, black and white cumin, coriander and basil are widely grown by farmers, research and extension could start intervention on these spices. Spice production would play great role in improving farmers’ livelihoods. Spices have been used as flavour, colour, aroma, enhancing agents and for preservation of foods. Moreover, more research is needed to improve the production and productivity of spices as well as to the improvement of the life of the farmers and play a role in the country economic growth.
Growth Performance of Purgi Goats under Field Conditions in Kargil District (Ladakh)
Authors: Alam Safeer , Rather Mubashir Ali , Nabi Nusrat , Kaur Gurjeet , Shanaz S. , Ahmad Nazir , Shah Ruksana , Ahmad Tavsief , Ahmad Mir Shabir , Hamadani Ambreen
Published: October 2021

Background: Purgi goats are native to Ladakh. They are used for fibre production and are known for the quality chevon. A study was, therefore, undertaken to study the effect of non-genetic factors on growth traits of Purgi Goats in its breeding tract. Methods: Flocks of 80 farmers from 8 villages of district Kargil were monitored to collect the data pertaining to growth traits during 2017 and 2018. The data so collected were suitably classified to study the major fixed effects like birth year, kid, parity of dam, season of birth and type of birth. Result: The averages were1.21±0.02, 3.62±0.02, 5.82±0.02, 8.73±0.03, 10.71±0.04 and 13.49±0.09 for BW, WW, 6MW, 9MW, 12MW and 18MW, respectively. The coefficients of variations of all the traits were low. Highest variability of 13.49 was observed for 18MW. The values of least squares means (LSM’s) of 0.96±0.05, 3.74±0.03, 5.80±0.05, 8.74±0.06, 10.87±0.08 and 13.91±0.19 for birthweight (BW), weaning weight (WW), six months body weight (6MW), nine months weight (9MW), yearling body weight (12MW) and eighteen months (18MW) weight were observed in the present study. The effects of sex of kids, season of birth and year of birth were significant (p less than 0.05) on all traits under study, whereas effect of birth-type was significant (p less than 0.05) on BW and WW and effect of parity was non-significant on all traits under study. All the traits BW, WW and 6MW were positively correlated among themselves. The correlations ranged from low (between BW and WW ) to high (WW with 9MW and 12MW).
Amaranth and Date Flavoured Milk
Authors: Patel Dasharath , Pinto Suneeta , Patel Sunil
Published: October 2021

Background: This project is aimed at developing a milk-based beverage combining the nutrient properties of milk, amaranth and dates. Inclusion of amaranth and dates in flavoured milk could provide product diversification and benefits to the health-conscious consumers. The objective of the present study was to develop a procedure for manufacture of an amaranth date flavoured milk (ADFM) using amaranth and date. Methods: To select the level of fat in milk, four batches of ADFM were prepared from milks containing different levels of milk fat viz. F1 (4.5%), F2 (3.0%), F3 (1.5%) and F4 (0.1%). To carry out their optimization in the final product formulation, the data was analysed using response surface methodology (RSM) using an advanced statistical software program named design expert (Version 8.0.3) was employed.
Result: On the basis of overall acceptability score, ADFM prepared from milk containing fat at 3.0% fat was preferred the most. From amongst different types and levels of stabilizing salts it was found that addition of 0.15% sodium citrate prevented coagulation during sterilization. The levels of roasted amaranth flour (% w/w of milk), date extract (% w/w of milk) and sugar (% w/w of milk) for preparation of ADFM was optimized using RSM with CCRD using three independent variables. The suggested solution from RSM analysis for ADFM was: level of roasted amaranth flour: 1.61 % w/w of milk, level of date extract: 5.16% w/w of milk and sugar: 6.0% w/w of milk. The developed product has 20.83% total solid, 2.77% fat, 3.07% protein, 14.15% carbohydrate, and 0.84% ash. Results of the study revealed that an acceptable quality ADFM can be manufactured by incorporating roasted amaranth and date.
Prevalence of Intestinal Parasite Infections in Stray Dogs in Taif Region, KSA
Authors: Malki Jamila S. Al
Published: October 2021

Background: The study of intestinal parasites that occur in stray dogs in the Taif region, KSA, is most important since there is little data available on this subject. Methods: Dog fecal samples were collected from 129 dogs in three different areas. Fecal samples were processed and analyzed by different mount techniques including, parasitological examination, wet-mount preparation and modified Kinyoun’s acid-fast technique. Result: The total prevalence of enteric parasites was 115 positive cases; for helminths was (62.7%) and for protozoa (26.3%). Mixed infection was higher than single infection in three areas. The total prevalence of helminths eggs by different mount preparation recovered from fecal sample examination from single or mixed form E. granulosus, T. canis and T. vulpis was of high infection rate (15.5%), (10.07%), (10.07%), followed by A. lumbercoides (7.7 %). Finally, T. leonine (6.9%), both A. caninum and A. braziliense are of the same percentage (6.2%). Concerning single and mixed protozoa infection, Giardia was of a high prevalence (16.2%), followed by Cryptosporidium (8.5%) and finally E. histolytica (1.5%) in fecal samples of doges. These data revealed that infection levels of parasites in stray dogs in the studied areas were high, knowing that this is the first study for mixed infections between dogs and humans in KSA.
Effect of Hydrogen Peroxide Pretreatment on Physiological and Biochemical Variables during Germination of Alfalfa Seeds
Authors: Muñoz-Salinas F. , Tovar-Pérez E.G. , Guevara-González R.G. , Loarca-Piña G.F. , Torres-Pacheco Irineo
Published: October 2021

Background: Hydrogen peroxide is reactive oxygen species that plays role in plant response to biotic and abiotic stress. The pretreatment with hydrogen peroxide can confer an adaptive capacity for the plants in unpredictable environments. The alfalfa (Medicago sativa L.) is the legume more utilized in animal feeding in the world. Moreover, the alfalfa sprouts are known for the phytochemicals that promote health with antioxidant properties. Methods: This work aimed to determine the effect of hydrogen peroxide in the pretreatment process of alfalfa seeds on variables as total germination, speed of germination, activity and antioxidant enzymes. The alfalfa seeds were soaked for 12 h in the next treatments 0, 98, 294, 490, 784, 980 mM of hydrogen peroxide. Result: The results showed that total germination was higher with the hydrogen peroxide than with water except 980 mM. The results of the present research indicated that hydrogen peroxide had physiological and biochemical effects on the germination processes of alfalfa.
The Szymkowiak’s over-expanded cycle in the rocker engine with the variable compression ratio – kinematics
Authors: Szwaja Stanisław , Szymkowiak Mirosław
Published: October 2021

The article discusses the innovative concept of the over-expanded thermodynamic cycle, the author of which is the Polish engineer-designer Mirosław Szymkowiak. This cycle is realized on the basis of a new and innovative, previously unknown design, of a piston-crankshaft linkage mechanism with the aid of an additional element known as a rocker arm. Additionally, the proposed mechanism allows for a smooth change of the compression/expansion ratio of the engine during its operation. In the beginning, the earlier conceptions of the rocker engine developed by Szymkowiak were presented, and then the main construction assumptions and kinematic calculations were described. It was confirmed, that the developed linkage has big potential in improving the engine's thermal efficiency by approximately 12% relative. Additionally, it significantly reduces the exhaust gas pressure, when the exhaust valve is opened, therefore, contributes to the reduction of the noise emitted by the engine.
Recent research on emerging organic electrode materials for energy storage
Authors: Huang Tao , Long Mengqi , Xiao Jun , Liu Hao , Wang Guoxiu
Published: October 2021

Due to the growth of the demand for rechargeable batteries in intelligent terminals, electric vehicles, energy storage, and other markets, electrode materials, as the essential of batteries, have attracted tremendous attention. The research of emerging organic electrode materials in batteries has been boosted recently to their advantages of low cost, environmental friendliness, biodegradability, and designability. This manuscript highlights and classifies several recent studies on organic electrode materials and lists their potential applications in various battery systems. Finally, the challenge and perspective of organic electrode materials are also summarized.
Thin-walled hollow fibers for flexible high energy density fiber-shaped supercapacitors
Authors: He Chuan , Cheng Jianli , Liu Yuhang , Zhang Xicui , Wang Bin
Published: October 2021

Fiber-shaped supercapacitors, which occupy minimal volume and possess remarkable flexibility, are particularly promising candidates for next-generation smart wearable devices. However, the state-of-the-art energy density and mechanical properties of fiber-shaped electrodes are far from satisfactory. Herein, hollow poly(3,4-ethylenedioxythiophene):polystyrene sulfonate thin-walled fibers (HPFs) are continuously prepared by coaxial wet-spinning. These HPFs combine a simple and high continuous preparation with high electrochemical performance and flexibility, owing to their hollow nature, small diameter (125 μm) and thin wall structure (8 μm). As a result, the HPFs display a specific areal capacitance of 115.2 mF cm-2 at a current density of 0.3 mA cm-2 with a high energy density of 9 μWh cm-2 at a power density of 0.112 mW cm-2. Furthermore, the HPFs maintain 81% of the initial capacitance after 10,000 cycles with ~100% Coulombic efficiency. More importantly, the specific capacitance is almost completely maintained after bending 3000 times at 180°.
QUALITY ANALYSIS OF "KOSMOS" TKKS COMPOSE USING SELULOTIC MICROORGANISM
Authors: Pramana Angga , Hamzah Anthony , Haitami Ahmad , Okalia Deno
Published: October 2021

This study aimed to determine the comparison of the chemical composition of oil oil palm empty friut bunches (TKKS) compost using cellulolytic microorganisms and TKKS compost. This research is a descriptive study that describes the chemical composition of compost with cellulolytic microorganisms. The treatments used in this study were the differences in the ratio of TKKS and cow dung KM1 (100: 0), KM2 (90:10), KM3 (80:20), KM4 (70:30), KM5 (60:40) and KM6 ( 50:50). This study's results were the selected treatment, namely KM5 with an N content of 0.73%, C-Organic 9.28%, C / N ratio 12.29%, P 0.42%, K 3.99%, while the TKKS content only. N 6.28%, C-Organic 14.19%, C / N ratio 2.26%, P 1.88%, K 2.51% and Mg 1.61%.
ANALISIS KEMITRAAN DAN PENGARUHNYA TERHADAP PENDAPATAN PETANI JAGUNG MADURA-3
Authors: Jakfar Abdul Azis , Vibriyanto Norita
Published: October 2021

The aims of this study are: 1) describe of implementation partnership on the Madura-3 corn in Bangkalan Regency. 2) analyze the income impact of partnerships on Madura-3 corn farmers in Bangkalan Regency. Type of this research are survey research and literature review. The data that used in this study are primary and secondary data. Primary data were obtained from direct sources of research objects, secondary data were obtained from literature studies, which consisted of research journals, reference books, data from related institutions, and other sources of reading material. This reseach use descriptive method that is describing the facts are occur at the study site. Results of this studies, there is advantage obtained from the partnership such as market guarantees so that income of Madura 3 corn farmers is higher than others corn farmers, pattern of partnership is the agribusiness operational cooperation.
PRODUKSI POLIHIDROKSIALKANOAT (PHA) OLEH MIKROBA KONSORSIA DENGAN PENAMBAHAN SUBSTRAT CRUDE GLYCEROL
Authors: Permatasari Vitta Rizky , Pentacolis Kevin Maris , Hidayat Nur , Suprayogi Suprayogi
Published: October 2021

Saat ini banyak penelitian mengenai penggunaan PHA (salah satu bahan baku pembuatan bioplastik) sebagai pengganti dari produksi plastik konvensional. Namun, produksi PHA masih sangat kecil dan terbatas. Hal ini disebabkan karena tingginya biaya produksi PHA. Pemanfaatan crude glycerol dan lumpur aktif sebagai sumber substrat/ sumber karbon dan bakteri penghasil PHA dapat menjadi solusi dalam penurunan biaya produksi PHA. Tujuan penelitian adalah menghasilkan PHA menggunakan crude glycerol dari mikroba konsorsia dan mengkarakterisasi PHA yang dihasilkan dari mikroba konsorsia berdasarkan perlakuan terbaik. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) non faktorial dengan 6 (enam) taraf perlakuan yaitu konsentrasi crude glycerol sebesar 10%, 20%, 30%, 40%, 50%, dan 60% (w/v) dengan waktu inkubasi 72 jam dan dilakukan 3 (tiga) kali ulangan. Data yang diperoleh dari hasil penelitian dianalisis menggunakan Analysis of Variaces (ANOVA) dan dilanjutkan uji Duncan. Hasil penelitian diketahui perlakuan konsentrasi crude glycerol berpengaruh nyata terhadap berat sel kering, berat PHA, rendemen PHA dan kadar gliserol termetabolisme. Berat sel kering PHA terbaik didapatkan pada perlakuan konsentrasi crude glycerol 20 % (20 gL-1) sebesar 2,867 gL-1, berat PHA sebesar 1,200 gL-1 dan rendemen PHA sebesar 42,03 %. Kadar gliserol termetabolisme tertinggi pada perlakuan konsentrasi 10 % (10 gL-1) dengan nilai 44,30 %. Selain itu, karakteristik gugus fungsi dengan FTIR didapatkan gugus C-O-C polimerik, C=O ester yang merupakan ciri khas polihidroksialkanoat (PHA). Juga terdapat gugus fungsi CH3 dan CH2 yang menandakan ciri khas Poli(3-hidroksibutirat) (PHB).
Simulasi Pengadaan Usaha Turunan Berbasis Buah dan Limbah Salak Pondoh untuk Meningkatan Pendapatan Industri Salak Pondoh di Kabupaten Sleman
Authors: Bimantio Muhammad Prasanto , Putra Dian Pratama
Published: October 2021

The high production of salak pondoh in Sleman Regency is not in line with the welfare of the farmers. The farmers receive a low price during the main harvest season, where the selling price per kilogram drops below the cost of production, so that the profit margins of farmers are not met. Abundant production during the main harvest and characteristics of perishable fruit are the cause of this problem, so that most farmers sell their crops to the nearest traders. This condition makes the bargaining position of farmers weak and the price determined by the traders, thus impacting on the decline in their welfare level. The purpose of this study is to formulate the salak pondoh business model in Sleman Regency in the form of dynamic simulations to carry out various scenarios of procuring business products based on raw materials in the form of fruit and waste from salak pondoh. The results of this simulation are expected to provide an alternative picture of solutions, steps, and conditions for academics, business people, and government in the form of a simulation template for each scenario. Data collection was carried out through direct observation to the salak pondoh place of business in Sleman Regency, brainstorming, interviews with related parties such as the salak pondoh association and the Sleman District Agriculture Office, and secondary data documentation on research topics. Scenarios of derivative business procurement (fruit and waste-based raw materials) provide a significant increase in income compared to business as usual business conditions, ranging from 4% - 44% in various fractions tested and up to 293% in extreme conditions and able to reduce the number of unemployed in Sleman Regency. The scenario of supplying derivative business made from pondoh salak fruit provides a significant increase in income compared to procurement of derivative business made from pondoh salak plant waste. It takes a probability value of sales of derivative products of more than 48.97% so that the revenue value from the business procurement scenario is greater than business as usual
Variabel Pengajuan Sertifikasi Halal Usaha Kecil Keripik Tempe di Kota Malang
Authors: Sucipto Sucipto , Syahputri Elvira Moudhy , Septifani Riska
Published: October 2021

Malang is one of the halal tourism destinations in Indonesia. Halal certification of superior food souvenirs such as tempeh chips is important to support halal tourism. In fact, the small business of halal certified chips is still limited. This study aimed to identify variables that affect the tempeh crispy small business submission for halal certification. The study used the Partial Least Square (PLS) method. Data was obtained from a questionnaire of 40 respondents consisting of 20 tempeh chips not halal certified and 20 businesses that were halal certified. Research variables include producer awareness, halal certification procedures, halal certification costs, halal certification regulations, and consumer demand. The results showed that the variable halal certification regulations and consumer demand significantly influence the submission of halal certification. Awareness and knowledge of producers of the procedures, costs, and benefits of halal certification can be increased in collaboration with the Halal Product Guarantee Agency (HPGA), the industrial offices of local government, and universities to provide information, improve, and assist producers to submit halal certification.
PEMETAAN MORFOLOGI DASAR PERAIRAN UNTUK PEMANTAUAN SEDIMENTASI DI DERMAGA PERIKANAN ULEE LHEU MENGGUNAKAN SINGLE BEAM ODOMETER DUA FREKUENSI
Authors: Rahmawan Guntur Adhi , Ondara Koko , Adnan Ilham
Published: October 2021

ABSTRACTUlee Lheu Fishing Port Jetty is an important port in Banda Aceh City which functions as a crossing, loading and unloading port. The issue of sedimentation is the main problem. This study aims to determine the morphology of the seabed as the basis for monitoring sedimentation at the Ulee Lheu Fishing Port Jetty. Bathymetric surveys were carried out in the dock pool using a single beam echotrack odometer. Tides were obtained using the IOC Sea Level Monitoring for 29 days and analyzed using the admiralty method. The results of the processing showed that there was sedimentation in the area of the Ulee Lheu Fishing Port Jetty. The depth of the wharf pool ranges from 0-7,7 meters with a sediment volume of 250.117,15 m3. Meanwhile, the tidal water type is included in the double daily tidal type with a value of F = 0,15 and the tidal distance is 2,38 meters and is included in the micro tidal range category and there is sedimentation in the Ulee Lheu Fishing Port Jetty.Keywords: Bathymetry, sedimentation, morphology, Ulee Lheu Port, tidal rangeABSTRAKDermaga Perikanan Ulee Lheu merupakan pelabuhan penting di Kota Banda Aceh yang difungsikan sebagai pelabuhan penyeberangan maupun sebagai pelabuhan bongkar muat. Isu sedimentasi menjadi masalah utama di dermaga ini. Penelitian ini bertujuan untuk mengetahui morfologi dasar laut sebagai dasar pemantauan sedimentasi di Dermaga Perikanan Ulee Lheu. Survei batimetri dilakukan di kolam dermaga menggunakan echotrack odometer single beam. Pasang surut diperoleh menggunakan dari IOC Sea Level Monitoring selama 29 hari serta dianalisa menggunakan metode admiralty. Hasil pengolahan menunjukan terjadi sedimentasi di areal Dermaga Perikanan. Kedalaman kolam dermaga berkisar antara 0-7,7 meter dengan volume sedimen berkisar 250.117,15 m3. Sementara tipe pasang surut perairan termasuk dalam tipe pasang surut harian ganda dengan nilai F=0,15 serta jarak tunggang pasut sebesar 2,38 meter  dan termasuk dalam kategori mikro tidal range dan terdapat sedimentasi di bagian Dermaga Perikanan Ulee Lheu.Kata Kunci : Batimetri, Sedimentasi, Morfologi, Dermaga Perikanan Ulee Lheu, tunggang pasang surut
Pengaruh Harga, Lokasi Dan Kualitas Pelayanan Terhadap Keputusan Pembelian Bahan Material Bangunan UD. Jaya Abadi Di Sampang
Authors: Firmansyah Salman , Setiyarini Triana
Published: October 2021

This study aims to empirically test price, location, and service quality on purchasing decisions for building materials at UD. Jaya Abadi in Sampang. Respondents in this study were consumers of UD. Jaya Abadi, who bought at least once. Sampling was selected using purposive sampling. The method of analysis used in this research is multiple linear regression. The results of this research hypothesis testing indicate that the price has an effect on purchasing decisions for building materials at UD. Jaya Abadi. Location affects the decision to purchase building materials at UD. Jaya Abadi. Service quality affects the decision to purchase building materials at UD. Jaya Abadi. Price, location, service quality simultaneously influence the purchasing decision for building materials at UD. Jaya Abadi.
Pengaruh Self-Efficacy terhadap Kinerja Melalui Kepuasan Kerja Sebagai Variabel Intervening (Study Pada Karyawan UD Indah Collection)
Authors: Siamita Nur , Ismail Iriani
Published: October 2021

The purposes of this studyare: 1) To determine whether self-efficacy has a positive and  significant  effect onemployees performance 2) To determine whether Self-efficacy has a positive and significant effect on job satisfaction 3) To determine whether job satisfaction has a positive and significant effect on  employees performance, 4) To  determine whether  Self-efficacy  have a positive and significant effect on employees performance through job satisfaction as an intervening variable. Based on path analysis, it found that Self-efficacy has a positive and significant effect on employees performance with a standardized coefficients betais 0.432 or 43.2%,  Self-efficacy has a positive and significant effect on job satisfaction with a beta standardized coefficients value is 0.857 or 85, 7%, Job satisfaction has a positive and significant effect on employees performance with a standardized coefficients beta value is 0.534 or 53.4%,  Self-efficacy has a positive and significant effect on   employees  performance  through   job  satisfaction  as  an  intervening variable by the value of standardized coefficients beta (self-efficacy on employees performance)and the effect of self-efficacy on job satisfaction is 0.857 x 0.534 = 0.457 or 45.7%.
Gaya Kepemimpinan Dalam Pengawasan Kerja Internal KPK Terhadap Kedisiplinan Kerja Dan Workplace Well-Being Pegawai
Authors: Imama Fitrotul , Balgies Soffy , Silvia Rohmatul Izzah , Kamilaini Laily Safira
Published: October 2021

Komisi Pemberantasan Korupsi atau yang biasa disingkat dengan KPK dikenal sebagai lembaga yang memiliki kuasa untuk memberantas korupsi di Indonesia. Tak heran jika hal-hal yang terdapat di KPK seperti gaya kepemimpinan, pengawasan kerja, disiplin kerja, dan lain sebagainya kerap mendapatkan atensi dan sorotan dari pemerintah hingga ke khalayak umum, serta kerap dikaji dari berbagai sudut pandang, termasuk dari sudut pandang psikologis. Tujuan dari kajian ini adalah untuk membahas tentang bagaimana kedisiplinan pegawai dalam internal KPK, berfokus pada bidang inspektorat yang baru dibentuk sebagai pelaku tindak disipliner beserta gaya kepemimpinan dan workplace well-being sehingga hasil kajian ini dapat bermanfaat untuk mencapai goals atau visi dan misi perusahaan dan organisasi. Studi literatur yang digunakan dalam kajian ini bersumber dari buku, jurnal, serta berita-berita yang memuat teori-teori serta pendapat para ahli mengenai fokus yang dibahas. Kajian ini mengaitkan antara hal-hal yang terdapat dalam internal KPK dengan sudut pandang psikologi industri dan organisasi.