bluuebunny/crossref_metadata_2025 huggingface dataset:
MULTIFRACTAL NATURE OF JUMPS IN THE BTC/USD
Authors: Сергей Александрович Михеев, , Оксана Анатольевна Нечаева, , Дмитрий Константинович Паршин, , Виктор Павлович Цветков, , Антон Ильич Цветков,
Published: January 2023

Целью работы является анализ курса BTC/USD с 01.01.2022 по 15.06.2022 на основе методов мультифрактальной динамики для исследования возможности прогноза скачков курса и выявления характерных маркеров скачков. Всего наблюдались 12 скачков с амплитудами в диапазоне 500-900 долл. в минуту. В работе показано, что такая высокая волатильность связана с мультифрактальной природой этих скачков. Анализ скачков курса BTC/USD был проведен в рамках модели мультифрактальной динамики. Кратко изложены основы мультифрактальной динамики, поскольку эта модель лежит в основе данной работы. В статье описываются уравнения этой модели, решения которых позволяют вычислить основные ее параметры для каждого большого скачка курса BTC/USD. Полученные в статье результаты указывают на высокую степень близости курса BTC/USD к мультифракталам на временных интервалах перед большими скачками. Показана бифуркационная природа скачков, связанная с мультифрактальным характером динамики курса BTC/USD перед его большими скачками. Необходимым условием скачка курса BTC/USD является близость значений параметров мультифрактальной динамики D 0 и Dk . Элементом научной новизны является выявленное свойство резкого скачка динамики курса BTC/USD после приближения фрактальной размерности локального тренда к значениям D 0 и Dk , которое может быть использовано при прогнозе возникновения больших скачков курса BTC/USD.

The aim of the work is to analyze the BTC/USD rate from 01/01/2022 to 06/15/2022 based on the methods of multifractal dynamics to study the possibility of forecasting rate jumps. A total of 12 jumps were observed with amplitudes in the range of $500-$900 per minute. The paper shows that such high volatility is associated with the multifractal nature of these jumps. The analysis of BTC/USD exchange rate fluctuations was carried out within the framework of the multifractal dynamics model. The basics of multifractal dynamics are briefly outlined, since this model underlies this work. The article describes the equations of this model, the solutions of which make it possible to calculate its main parameters for each big jump in the BTC/USD rate. The results obtained in the article indicate a high degree of proximity of the BTC/USD rate to multifractals at time intervals before large jumps. The bifurcation nature of the jumps is shown, which is associated with the multifractal nature of the dynamics of the BTC/USD rate before its big jumps. Table data. 3 indicate that the necessary condition for the jump in the BTC/USD rate is the proximity of the values of the multifractal dynamics parameters D0 and Dk . An element of scientific novelty is the identified property of a sharp jump in the dynamics of the BTC/USD exchange rate after the fractal dimension of the local trend approaches the values of D0 and Dk , which can be used to predict the occurrence of large jumps in the BTC/USD exchange rate.
SOCIOLOGICAL FEATURES OF THE ORGANIZATION OF TOURISM ACTIVITIES IN THE KIROV’S REGION: A COMPARATIVE ANALYSIS
Authors: Елизавета Сергеевна Малых, , Алина Константиновна Синцова, , Алевтина Александровна Веприкова, , Алёна Игоревна Сметанина,
Published: January 2023

В статье раскрываются результаты анкетирования по изучению туристско-рекреационных потребностей жителей Кировской области (относительно Кирово-Чепецкого и Советского районов). Были проанализированы туристские потребности жителей Кировской области, а также их основные составляющие, такие как питание, размещение, транспорт, виды экскурсионных программ, дополнительные услуги, сезонность и стоимость туристских услуг. Основным методом является сплошное анкетирование в социальных сетях, где было опрошено 200 респондентов. В результате анализа было выявлено следующее: туристские потребности жителей Кировской области (относительно Советского и Кирово-Чепецкого районов) имеют много общего. При этом выявлен основной перечень предпочтений клиентов туристских услуг.

In the article the authors reveal the results of a survey on tourist recreational needs of Kirov's Oblast residents (in relation to Kirovo-Chepetskiy and Sovetskiy municipal district). Tourist needs of the Kirov's region residents and their main components were analyzed. These are food, accommodation, transportation, types of excursion programs, additional services, seasonality, and cost of tourist services. The main method of analysis is a complete survey in social networks by which 200 respondents were interviewed. The analysis has revealed the following: tourist needs of Kirov's region residents (about the Sovetskiy and Kirovo-Chepetskiy municipal districts) have much in common. At the same time, the main list of customer preferences for tourism services has been revealed.
KEY FEATURES AND DIRECTIONS OF TRANSFORMATION OF THE SOCIO-GEOGRAPHICAL SPACE OF A SMALL CITY (ON THE EXAMPLE OF ZUBTSOV, TVER REGION)
Authors: Илья Петрович Смирнов, , Галина Олеговна Козловская,
Published: January 2023

Статья посвящена крупномасштабному исследования пространства малого города Зубцова Тверской области. Теоретической основой работы стала концептуальная идея о социально-географическом пространстве. В статье предпринята попытка систематизации пространственного выражения городских проблем. Особое внимание уделено структурным особенностям социально-географического пространства Зубцова. Город обладает рассеченным сложным пространством, которое сложилось под влиянием двух относительно крупных рек - Волги и Вазузы. В статье проведен анализ влияния пространственной структуры на устройство сферы услуг и размещения ареалов концентрации населения. С помощью ретроспективного анализа установлен факт дрейфа основного ареала обслуживания из исторической части на территорию позднесоветского микрорайона. На основе полевых исследований составлен ментальный портрет города и его отдельных вернакулярных районов.

The article is devoted to a large-scale study of the space of the small city of Zubtsov, Tver region. The theoretical basis of the work was the conceptual idea of socio-geographical space. The article attempts to systematize the spatial expression of urban problems. Special attention is paid to the structural features of the socio-geographical space of Zubtsov. The city has a dissected complex space, which was formed under the influence of two relatively large rivers - the Volga and the Vazuza. The article analyzes the influence of spatial structure on the structure of the service sector and the placement of areas of population concentration. With the help of a retrospective analysis, the fact of the drift of the main service area from the historical part to the territory of the late Soviet microdistrict was established. Based on field research, a mental portrait of the city and its individual vernacular districts has been compiled.
IR-SPECTROSCOPIC STUDY OF THE POLYMORPHISM OF STREPTOCID AND INDOMETACIN DRUGS
Authors: Кристина Сергеевна Шачнева, , Надежда Владимировна Баранова, , Мариана Александровна Феофанова,
Published: January 2023

Проведено ИК-спектроскопическое определение стрептоцида и индометацина в исследуемых образцах и исследование их полиморфных модификаций. Получены полиморфные модификаций сульфаниламида из воды и этилового спирта. Получены ИК-спектры стрептоцида αромбической и β-моноклинной модификаций, γ-модификации индометацина. Подтверждено влияние перекристаллизации и таблетирования с бромидом калия на полиморфные превращения.

An IR spectroscopic determination of streptocide and indomethacin in the studied samples and a study of their polymorphic modifications were carried out. Polymorphic modifications of sulfanilamide were obtained from various solvents such as water and ethyl alcohol. IR-spectra of streptocide of αrhombic and β-monoclinic modifications, γ-modification of indomethacin were obtained. The effect of recrystallization and tabletting with potassium bromide on polymorphic transformations was confirmed.
SYNTHESIS AND STUDY OF THE CHEMILUMINESCENT PROPERTIES OF CONDENSED THIOHYDANTOINS OF THE SERIES OF SPINACIN AND TETRAHYDRO-β-CARBOLINE
Authors: Маргарита Григорьевна Абрамянц, , Иван Дмитриевич Одарюк, , Елена Михайловна Кравченко, , Дмитрий Александрович Ломов,
Published: January 2023

Усовершенствованным методом синтезирован ряд производных конденсированных тиогидантоинов спинацина и β -карболина. Полученные соединения обладают интенсивной хемилюминесценцией в щелочных растворах диметилсульфоксида и диметилформамида.

A number of derivatives of condensed thiohydantoins spinacin and β carboline have been synthesized by an improved method. The resulting compounds have intense chemiluminescence in alkaline solutions of dimethyl sulfoxide and dimethylformamide.
COMPUTER MODELING OF LANTHANIDE COMPLEXES WITH AMPICILLIN
Authors: Екатерина Андреевна Макарова, , Мария Владимировна Минина, , Владимир Георгиевич Алексеев, , Мариана Александровна Феофанова,
Published: January 2023

Проведен расчет структуры комплексов ампициллина с катионами лантаноидов методом DFT, определены длины связей ионов лантаноидов с донорными атомами лигандов, получены энергии комплексов. Установлено, что энергия комплексов, рассчитанная методом DFT, находится в монотонной зависимости от экспериментально определенных констант их образования.

The structure of ampicillin complexes with lanthanide cations was calculated by the DFT method, the bond lengths of lanthanide ions with donor ligand atoms were determined, and the complex energies were obtained. It is established that the energy of complexes calculated by the DFT method is monotonically dependent on experimentally determined constants of their formation.
Evaluation of Anti-oxidant and Bio Active Quantification of Vigna unguiculata Seed Extracts
Authors: ME Prashanth , H Basavaraj , Shalavadi Mallappa
Published: January 2023

Background and Aim Vigna unguiculata is an edible legume belonging to the Fabaceae family. The study aims to Evaluate Anti-oxidant and Bio Active Quantification of Vigna unguiculata Seed ExtractsMethodology The current study aimed to prepare extracts of Vigna unguiculata with distilled water 50 ethanol and 70 acetone as solvents which were then inspected for anti-oxidant activity employing DPPH 11-Diphenyl-2-picrylhydrazy and Nitric oxide scavenging assays with vitamin C as standard. The extracts were also subjected to bioactive quantification to determine the flavonoid and phenolic contents using Quercetin and Gallic acid as standards respectively.Results The results demonstrated the acetone extract of Vigna unguiculata to have greater antioxidant ability and higher bioactive concentration. Acetone extract might be used in a variety of pharmacological studies owing to its antioxidant and bioactive profile.Conclusion The presented study conclude that acetone extract might be useful in a variety of pharmacological studies owing to its antioxidant and bioactive profile.nbsp
Analytical Method Development and Validation for the Simultaneous Estimation of Rifampicin and Isoniazid in its Bulk and Pharmaceutical Dosage Forms by RP-HPLC
Authors: B Manjushree , Richards M Paul , D Suchitra , BA Vishwanath
Published: January 2023

Background A combination of Rifampicin and Isoniazid is the drug of choice to treat tuberculosis patients in sustenance or those travelling to a region where there is a probability of being infected with tuberculosis.Objective The main objective of the simultaneous estimation of combined drug was to establish identity purity physical characteristics and potency of the drugs.Methodology The chromatographic environment was fortunately evolved for the partition of Rifampicin and Isoniazid by using column thermosil RPC18 4.5times100 nm 5.0 microm flow rate was 1 mLmin mobile phase ratio was 7030 vv methanolsodium acetate buffer. A pH of 3 was adjusted with Ortho phosphoric acid wavelength was detected at 240 nm. Column dimensions were Thermosil C184.6times100mm 5.0 microm.Results The results were in good agreement with those obtained with official HPLC with absorption maximum at 240 nm by preparing mobile phase 7030 methanolsodium acetate buffer with a flow rate 1 mLmin and it ran for 5 minutes by selecting thermosil RPC18 4.5times100 nm of ambient temperature. All the results obtained were precise accurate and robust as per international conference on Harmonization ICH guidelines.Conclusion It can be concluded that the proposed Reverse Phase High Performance Liquid Chromatographic RPHPLC method is accurate precise sensitive specific robust and reproducible for the simultaneous analysis of Rifampicin and Isoniazid with less tailing factor and is also economical. Thermosil RPC18 4.5times100 nm 5.0 microm flow rate was 1 mLmin. Both the samples were in the range of 200 to 400 nm and maximum wavelength was identified at 240 nm.
Pharmacological Investigation of Cassia hirsuta Seed Extract for its Anti-inflammatory Activity in Acute and Chronic Inflammatory Animal Models
Authors: G Chandana , H Basavaraj , ME Prashanth , Hanamantappa Shalavadi Mallappa
Published: January 2023

Objective The declared goal of this research was to investigate anti-inflammatory and anti-arthritic effectiveness of ethanolic extract of Cassia hirsuta seeds EECH in animals employing Carrageenan-induced paw CIP edema and Complete Freundrsquos adjuvant CFA induced arthritis models.Methodology The seeds of Cassia hirsuta were collected shade dried extracted using ethanol in Soxhlet extractor and the extract was tested for phytochemicals and acute oral toxicity 423 - OECD guidelines. CIP edema was examined to ascertain anti-inflammatory property. The anti-arthritic activity of CFA was analyzed by measuring paw volume arthritic index and body weight. Hematological parameters and markers in serum levels of enzymes like SGPT SGOT serum RF and histopathological studies were also performed.Results The seed extract possessed various phytoconstituents like alkaloids flavonoids terpenoids phenols and tannins as active constituents. In acute oral toxicity study the EECH produced no lethality with maximum dose of up to 2000 mgkg bw. Hence 120th 110th amp 15th mgkg b.w were taken as lower moderate and higher dose respectively. EECH at concentration of 100 200 amp 400 mgkg was able to reduce the inflammation induced by carrageenan in rats. However 200 mgkg 400 mgkg has shown significant inhibition of arthritis in rats when challenged with CFA 0.1 mL. The EECH of dose 200 mgkg 400 mgkg had maintained normal architecture of bone normal areolar synovium and normal histology in comparison to arthritis control.Conclusion According to our findings the EECH demonstrated anti-oxidant anti-inflammatory amp antiarthritic activity in a dose-dependent manner. The phytoconstituents like flavonoids terpenoids and phenols as active constituents in the extract may justify its activity.nbsp
Análise dos custos de transportes: um estudo de caso em veículo de distribuição urbana
Authors:   Universidade Federal de Uberlândia, Saraiva Junior Renato , Maia Leonardo Caixeta de Castro ,   Universidade Federal de Uberlândia
Published: January 2023

Este artigo tem como objetivo principal identificar e analisar os custos logísticos, na atividade de logística de distribuição urbana. O levantamento dos dados foi realizado em uma empresa com frota própria e limitou-se à análise dos custos de oficina e de combustíveis de um único modelo de caminhão da fabricante Volkswagen, modelo 9.160 DELIVERY do ano de 2013. Adicionalmente à coleta de dados, avaliou-se o mapeamento da forma de condução do veículo pelo motorista e seu reflexo nos custos operacionais. Portanto, o presente trabalho é de carácter descritivo e iniciou-se a partir de uma pesquisa bibliográfica e posteriormente uma conciliação com os dados da empresa. Por fim, utilizou-se o diagrama de Ishikawa para reconhecer as principais causas para um efeito não desejado: custos logísticos fora de controle. Os resultados da pesquisa evidenciam que a mediana do custo de combustível com esta frota é de R$ 0,84/km e as despesas com oficina possui mediana de R$0,24/km, totalizando R$ 1,08 por km rodado. Após análise dos dados e identificadas as melhores práticas, foram realizadas entrevistas com quatro motoristas para descobrir o que esses recursos fazem de diferente que conseguem se destacar com bons resultados. A contribuição do trabalho quanto à visão empresarial está relacionada à apresentação de dados de um modelo de veículo para entrega urbana e a possibilidade de utilização da internet das coisas (IOT) como mecanismo de monitoramento, controle e melhoria contínua; quanto à visão acadêmica, expõe-se um levantamento de dados primários no qual as práticas de treinamento e seleção de motoristas e de controle de oficina são moderadas pelo nível de utilização da tecnologia para o monitoramento dos processos logísticos buscando melhores níveis de desempenho.
Atribuições de causalidade para explicar o que motivam os alunos de contabilidade para a escolha da temática do trabalho de conclusão de curso e as reações emocionais provocadas
Authors:   Universidade Federal Rural do Semi-Árido, Sena Alyson Daniel Costa , Moreira Caritsa Scartaty ,   Universidade Federal Rural do Semi-Árido, Souza Jocykleber Meireles de ,   Universidade Federal Rural do Semi-Árido
Published: January 2023

O presente estudo tem por objetivo identificar as motivações atribuídas pelos discentes de Ciências Contábeis na escolha da temática do Trabalho de Conclusão de Curso (TCC) e as reações emocionais provocadas a luz da Teoria Atribucional Causal. Os dados foram coletados por meio de um questionário aplicado com os alunos da Universidade Federal do Semi-Árido (UFERSA) e da Universidade Estadual do Rio Grande do Norte (UERN). Para análise de resultados, utilizou-se a estatística descritiva para a análise das perguntas fechadas e a técnica de análise de conteúdo para as respostas discursivas dos discentes. Os resultados evidenciaram que as motivações atribuídas pelos discentes para a escolha da temática do TCC encontradas foram o esforço e a capacidade e a ajuda do professor. Sobre as reações emocionais provocadas, a maior parte dos discentes declararam se sentir motivados com a temática escolhida para o TCC devido a afinidade pelo tema e a ajuda do professor.
Risco de morte em acidentes ocorridos nas rodovias federais brasileiras
Authors:   Universidade Federal da Paraíba, Costa Júnior Eduardo Elias da , Santos Júnior Luiz Carlos
Published: January 2023

O número de acidentes de trânsito em rodovias federais brasileiras se configura como um grave problema de saúde pública no país, não apenas pelos custos associados ao atendimento e internação das vítimas, mas também pela morte precoce de uma parte da população considerada economicamente ativa. Dado o contexto, este trabalho tem como objetivo analisar a ocorrência de vítimas fatais em acidentes de trânsito nas rodovias federais brasileiras. Para isso, utilizam-se de dados disponibilizados pela Polícia Rodoviária Federal (PRF), entre os anos de 2017 e 2019, além do modelo de regressão logística em linguagem R. Dentre os principais resultados, destaca-se o registro de 184.635 acidentes nas rodovias federais brasileiras, no qual 11.340 acidentes apresentaram ocorrência de morte (vítimas fatais) e 173.295 de acidentes sem vítimas fatais (feridos e ilesos), representando um percentual de, respectivamente, 6,14% e, 93,86% dos acidentes. Constatou-se que os fatores que mais agravam o risco de morte são: acidentes ocorridos aos domingos, na região Nordeste, provocados por erro do pedestre, ao amanhecer, com céu limpo, em pista simples, traçado de desvio temporário e em zona rural. Tais resultados possibilitam a elaboração e adoção de políticas de prevenção por parte da esfera pública, a fim de reduzir o número de óbitos em acidentes ocorridos em rodovias federais.
Expectativa de vida com e sem doença crônica de coluna no Brasil
Authors:   Universidade Federal do Ceará, Mendonça Marília Melo , Rocha Alane Siqueira ,   Universidade Federal do Ceará
Published: January 2023

Este artigo tem como objetivo geral estimar a expectativa de vida com e sem doença crônica de coluna para a população brasileira, dividida por sexo e em diferentes faixas etárias. Os períodos analisados são os anos de 2013 e 2019, últimas edições da Pesquisa Nacional de Saúde (PNS). Os dados de prevalência de Doença Crônica de Coluna e Tábuas de Mortalidade, necessários para o cálculo das medidas propostas, foram obtidos, respectivamente, a partir da PNS e estimativas do IBGE. O método de Sullivan foi adotado para o cálculo da expectativa de vida com ou sem o problema crônico de coluna. Como resultado, observou-se que as mulheres vivem, em todas idades e períodos analisados, mais anos com algum problema crônico de coluna. As mulheres idosas apresentam maior prevalência da doença, quando comparadas às mais jovens. No geral houve um aumento da prevalência e tempo médio vivido com doença crônica de coluna entre os anos de 2013 e 2019.
Sensitivity of the North Caucasian and Belarusian populations of Microdochium nivale (Fr.) Samuels & hallet to fungicides
Authors: Volkova G. V. , Yakhnik Ya. V. , Zhukovsky A. G.
Published: January 2023

Pink snow rot (pathogen Microdochium nivale) is the most common low-temperature pathogen worldwide. Sensitivity of two geographically distant populations of the pink snow rot pathogen (southern Russia and the Republic of Belarus) to nine modern fungicides was studied. The fungicides included in the State Catalogue of pesticides and agrochemicals permitted for use in the Russian Federation and recommended for treatment against snow rot were selected for the study. The material for the study was a pure culture of the fungus M. nivale. The agar block method was used in this study. The fungicide solutions were introduced into the nutrient medium using two standard methods: by interfering with the medium and by rubbing the preparation on the medium surface with a spatula. The preparations with 100% fungicidal effect against both studied populations were identified: Polaris, OE, Quinto Duo, SC and Bariton Super, SC. Oplot Trio, WS, Vybrance Trio, FC, Maxim Forte, SC showed 100% efficacy only against the Belarusian population of the pathogen. It was determined that the use of two methods of introducing the preparation into the nutrient medium (intervention and rubbing on the agar surface) has a high correlation coefficient (for the Belarusian population - rxy = 1.0, for the North Caucasian population - rxy = 0.99). However, intervention is less likely to inhibit colony growth and is therefore preferable in drug sensitivity studies of pure culture of the fungus M. nivale. A statistically significant difference was found between the sensitivity to fungicides of populations from geographically distant regions (Ft 5.32 < Ff 23.2 for the intervention method, Ft 5.32 < Ff 37.7 for the rubbing method). The data indicate the heterogeneity of the snow rot pathogen in terms of sensitivity to the modern assortment of seed dressing agents.
Study of the effect of the dehydration process on the quality and safety of animal feed
Authors: Razumovskaya E. S.
Published: January 2023

The stages of dry feed production for unproductive animals and the results of the research of the resulting products for compliance with GOSTs are presented. The quality and safety parameters of dry feeds for unproductive animals made of raw materials of animal origin subjected to dehydration process have been studied. It was found that the drying process with the convection principle of action, positively affects the indicators of nutritional value of the finished product. The resulting products comply with GOST R 54954-2012. The experiment was conducted in 2021, 2022. Spleens obtained from clinically healthy cattle (age 18 months) during slaughter at the meat processing enterprises of the Altai Territory were used as an object of the study. According to the laboratory results, it was found that in the studied form of raw materials in the process of dehydration such an indicator as the mass fraction of moisture significantly decreased and amounted to 5.5 ± 0.01%. The indicators of the mass fraction of protein and ash after the drying process, remained virtually unchanged: 20.27 ± 0.001 and 0.05 ± 0.01% respectively. The mass fraction of crude fat in the studied samples was 0.4 ± 0.01%, which is 4.6-8.6% lower than the standard. Study of the resulting products for compliance with the requirements for dry full-fat adult fodder (dogs) was carried out. A comparative analysis of the chemical composition of dry feed samples was conducted. In the tested samples the required content of the following essential macronutrients: phosphorus, calcium and sodium was observed. The highest calcium content (2.3%) was detected. Laboratory methods in accordance with the approved rules of bacterial studies established safety indicators of dry animal feed for unproductive animals.
Using Bacillus subtilis as an oral vaccine carrier against Streptococcus suis
Authors: Afonyushkin V. N. , Fudi Y. , Mironova T. E. , Nefedova E. V. , Kilp A. S. , Koptev V. Yu. , Donchenko N. A.
Published: January 2023

Due to the progressive growth of the bacteria caused by the widespread use of antibiotics, treatment of streptococcosis is becoming increasingly difficult. Reliable vaccination against Streptococcus suis is necessary. Modern molecular diagnostic and genetic engineering capabilities create prospects for direct cloning of the protective epitopes of the Lmb gene of the local S. suis strain into the proposed delivery system of the pig immune system antigen. Among oral vaccine carriers, Bacillus subtilis is recognized as a relatively environmentally friendly carrier with an efficient protein secretion system and adaptive metabolism capable of spore production under relatively harsh conditions. This spore property can be used to increase the stability and reusability of vaccines. The possibility of using the protective Lmb epitopes of S. suis in B. subtilis as a carrier of an oral recombinant vaccine against Streptococcus suis was studied. The nucleotide sequences of S. suis were obtained from the GenBank database after a preliminary analysis of literature data on the known protective antigens of S. suis of various serotypes. Nucleotide sequence analysis was performed using Unipro UGENE v. 43.0. The Immune Epitope Database (IEDB) was used to search for T (CTL and Th) and B dependent epitopes of the Lmb gene. A computer-designed vaccine in which localization of CTL, B, and Th epitopes is predicted is described. The results of cloning the sequence of the antigenically active epitope of the S. suis Lmb protein in B. subtilis for subsequent oral administration and study of changes in immunological reactions and adverse reactions in animals are described. The possibility to clone the epitopes of recombinant S. suis Lmb protein into the pBE-S polylinker vector was revealed. In the long term, it seems possible to create a new inexpensive and easy-to-use vaccine against S. suis that does not require injection.
ETHNOVETERINARY PRACTICES: A REVIEW OF PHYTOTHERAPEUTICAL APPROACHES IN THE TREATMENT OF LIVESTOCK IN AFRICA: CASE OF CAMEROON
Authors: Tebug T. Tumasang , Julius Awah Ndukum , Niba Aziwo Tatanja , Kameni Serge Leugoué , Jemima Guiekep Nounamo Arthénice
Published: January 2023

Livestock health is a vital production factor in all production units. In the developed world, a lot of resources are invested in preventive measures unlike in the developing countries where resources are geared toward curative methods of livestock health care. Smallholder livestock production is an important sector of Cameroon’s economy, therefore for a sustainable production there should be a good livestock health care system. In Cameroon, livestock production is entrusted to poor, old and illiterate’s farmers with their indigenous methods of keeping livestock healthy and productive. For Cameroon to increase production, ethno veterinary medicine, which is adapted and affordable to smallholder breeders, should be developed for a sustainable smallholder production. Over 90% of the materials used in ethno veterinary medicine are from plants, hence there is an urgent need to conserve and propagate the medicinal plants already identified for fear of extinction due to random harvesting. Since ethno veterinary plants will be continuously used by smallholder livestock producers, there is a need to development ethno veterinary gardens for a sustainable use and conservation of these plants’ species for future generations. More research is needed to evaluate and validate the ethno veterinary properties of these plants’ preparations through collaboration between the ethno veterinary practitioners and researchers.
THE EPIDEMIC CONTROL PROCESS, THE CORONA VIRUS, MATHEMATICAL MODELING
Authors: Domínguez Sandy Sánchez , García Adolfo Fernández , Ruiz Chaveco Antonio Iván
Published: January 2023

In the present work, a study is made of the development of epidemics, in particular the one referring to the epidemic transmitted by SAR CoV 2; a model is developed through a system of Differential Equations that simulates this process, the system is simplified, if it makes a qualitative study of the trajectories of the system giving conclusions regarding the hole behavior of the trajectories, thus proving control of the epidemic; a critical case is treated and an example is presented that responds to the conditions of the introduced critical case, graphically proving the conclusions demonstrated analytically.
Improvement of growth and yield of organic broccoli (Brassica oleracea var. Italica) by application of different organic materials combination
Authors: Lilik Tri Indriyati  , Nugroho Budi
Published: January 2023

Pot experiment was conducted to evaluate the effect of organic materials combination on improvement of growth and yield of organic broccoli. There were 19 treatments in total consisted of four types organic materials that were azolla (A), vermicompost (V), cow dung (S), and chicken manure (F) applied in combination, blank control, and inorganic fertilizer as comparison standard. The experiment results showed that application of organic materials combination significantly increased the growth of plant, diameter head and yield of broccoli compared with untreated soil and inorganic fertilizer treatment.  The addition of dolomite into the organic materials combination tended to decrease the growth and yield of broccoli than no addition of dolomite. However, the addition of chicken manure into the combination showed higher growth and yield of broccoli. The best combination of organic materials in raising the growth and yield of broccoli was azolla, and chicken manure (A+F).
Efektivitas Konseling Marital Untuk Mengembangkan Gaya Penyelesaian Konflik Yang Konstruktif Pada Pasangan
Authors: Hutami Oksatriani Susilo , Sadarjoen Sawitri Supardi , Nugraha Suci
Published: January 2023

Konflik ataupun perselisihan perkawinan yang belum terselesaikan biasanya mengakibatkan turunnya tingkat kesejahteraan diri pasangan. Penelitian ini bertujuan untuk mengembangkan gaya penyelesaian konflik antara pasangan yang telah menikah dibawah 5 tahun melalui pendekatan konseling marital dan mengembangkan konflik yang konstruktif, diharapkan menyelesaikan konflik secara  konstruktif. Penyusunan konseling marital dengan menggunakan pendekatan konstruktif dari Olson (2006) pertama kali diuji coba pada dua pasangan suami istri yang berada pada usia pernikahan < 5 tahun di kota Bandung, Jawa Barat. Hasil menunjukkan bahwa konseling marital ini bisa meningkatkan pemahaman partisipan mengenai konflik perkawinan yang konstruktif. Selain itu, konseling marital bisa mengembangkan gaya penyelesaian konflik antra pasangan yang sudah menikah < 5 tahun perkawinan dengan menyelesaikan konseling marital secara konstruktif. Hal ini dikarenakan sebagian besar partisipan menganggap bahwa tujuan konseling ini menjadi realistis dan relevan bagi mereka. Selanjutnya, tujuan para partisipan dapat dicapai sesuai dalam pembelajaran dengan pendekatan atau metode konstruktif.
Efektivitas Media Manipulatif Slime Dalam Mengembangkan Kemampuan Motorik Halus Anak Usia Dini
Authors: Erhamwilda Erhamwilda , Rasyid A Mujahid , Rustini Rinrin
Published: January 2023

Ditemukan bahwa kemampuan motorik halus anak kelompok A di TK BPP Malati kecamatan Cilaku Kabupaten Cianjur yang masih belum berkembang secara optimal. Hal ini dikarenakan kesadaran orang tua hanya memperhatikan aspek perkembangan kognitif anak saja pada bidang baca,tulis dan hitung. Salah satu bahan bermain yang mainkan otot-otot halus anak adalah slime. Adapun tujuan penelitian ini adalah untuk mengetahui kondisi objektif kemampuan motorik halus anak kelompok A TK BPP Malati dengan media manipulatif slimeJenis penelitian yang digunakan peneliti menggunakan metode kuantitatif kuasi eksperimen. Penelitian dilakukan pada TK BPP Malati di kecamatan Cilaku, Kabupaten Cianjur tahun ajaran 2018-2019. Sampel penelitian ini adalah seluruh siswa siswi kelompok A (usia 4-5 tahun) berjumlah 20 anak. Teknik sampling yang digunakan adalah Random sampling. Hasil penelitian menunjukkan penerapan media manipulatif slime dalam meningkatkan motorik halus anak dapat disimpulkan berhasil, hal tersebut dibuktikan pencapaian setelah dilakukan tes pada saat kegiatan.
Profil Mutu Lembaga PAUD Nonformal Kecamatan Cilawu Kabupaten Garut
Authors: Safrudin Irfan , Halimi Agus , Daryana Andepi
Published: January 2023

Beragamnya performance mutu 12 lembaga PAUD non formal di Kecamatan Cilawu Kabupaten Garut setelah akreditasi mencerminkan kualitas mutu lembaga PAUD yang dikelolanya. Kriteria tentang pengelolaan dan penyelenggaraan PAUD di seluruh wilayah hukum  Negara Kesatuan Republik Indonesia telah diatur berdasarkan  Peraturan Mentri Pendidikan dan Kebudayaan Republik Indonesia  no 137 tahun 2013  tentang Standar Nasional Pendidikan Anak Usia Dini yang meliputi delapan standar nasional PAUD yang harus terdokumentasikan lengkap, sesuai dengan pedoman standar nasional PAUD, serta terimplementasikan dalam kehidupan sehari-hari di lembaga PAUD. Penelitian ini bertujuan untuk mengetahui gambaran kualitas mutu lembaga PAUD  non formal di Kecamatan Cilawu Kabupaten Garut sebelum dan setelah diakreditasi. Melalui analisis data dan pengujian hipotesis dengan menggunakan uji t (t test)  maka dihasilkan profil mutu lembaga PAUD non formal di Kecamatan Cilawu Kabupaten Garut dan adanya pengaruh nilai mutu sebelum akreditasi terhadap nilai mutu setelah akreditasi.
Analisis Kebutuhan Mutu Pelayanan Dengan Mengintegrasikan Total Quality Manajemen Dengan SERVQUAL
Authors: Khairunnisa Elsa Nurfiani
Published: January 2023

Rumah sakit harus meningkatkan mutu pelayanan secara terus-menerus untuk memperoleh kepercayaan dari masyarakat dan agar mampu bersaing dengan rumah sakit lainnya. Salah satu strategi yang tepat dalam mengantisipasi persaingan yang semakin terbuka adalah melalui upaya peningkatan mutu pelayanan kesehatan rumah sakit melalui Total Quality Management (TQM) dari Donabedian melalui tiga pendekatan. Selain itu rumah sakit harus memperhatikan dimensi kualitas layanan (SERVQUAL) yang sangat mempengaruhi kepuasan pasien. Penelitian ini bertujuan untuk mengetahui kebutuhan mutu sumber daya manusia (SDM), sarana dan prasarana sesuai TQM dengan standar lainnya. Sampel yang digunakan sebanyak 380 orang dari semua pasien instalasi rawat jalan RSUD Cideres dengan teknik simple random sampling. Hasil analisis data diketahui bahwa dimensi gap tertinggi terdapat pada dimensi Reliability/Keandalan dengan gap -0,83. Indeks kepuasan pasien berada pada interval 0,66 - 0,80 yang berarti secara keseluruhan pasien Rawat Jalan RSUD Cideres merasa puas atas pelayanan kesehatan.
Diseminasi kelompok Karang Taruna Desa Pationgi dalam pembuatan Biofoam kemasan pengganti Styrofoam
Authors:   Universitas Muhammadiyah Bone, Erviana Irna , Asfar Andi Muhammad Irfan Taufan ,   Universitas Muhammadiyah Bone, Asfar Andi Muhamad Iqbal Akbar ,   Politeknik Negeri Ujung Pandang, Safar Muhamamd ,   Universitas Muhammadiyah Bone, Dewi Sartika Sari ,   Universitas Muhammadiyah Bone, Damayanti Wiwi ,   Universitas Muhammadiyah Bone, Yulita Yulita ,   Universitas Muhammadiyah Bone
Published: January 2023

Bio foam is an alternative packaging to replace Styrofoam made from natural raw materials such as starch, with the addition of fiber to strengthen its structure. Bio foam is a product that is not only biodegradable but also renewable. The raw material for packaging bio-foam in this service activity is peanut shell waste, a combination of rice husk waste. Peanut shell and rice husk waste are used as ingredients in manufacturing bio-foam because these materials contain high carbon elements, producing K-dots compounds that can benefit human life if processed. This service activity was carried out in Pationgi Village, Patimpeng District, Bone Regency, with three main stages: counseling, training, and mentoring. This community service activity aims to provide knowledge and skills to Karang Taruna Group partners in processing peanut shell waste and rice husks into environmentally friendly alternative packaging (bio-foam) as a substitute for Styrofoam. As a result of this community service, the Pationgi Village Youth Group partners now have more knowledge and skills about how to process nutshell and rice husk waste to make bio-foam packaging that is better for the environment and can be used instead of Styrofoam.
"Connecting the past, present and future generations": reflecting on the main promising ideas of K. D. Ushinsky’s methodological legacy (to the 200th anniversary of the birth)
Authors: Antonova L. G. , Gaponova Zh. K. , Tishko A. B.
Published: January 2023

The paper explores the most significant aspects of K. D. Ushinsky’s biography and pedagogical legacy relevant to the modern practice of liberal education. The biographical information about the famous teacher we provide testifies to the special influence of his family, gymnasium teachers, famous university professors on the formation of K. D. Ushinsky’s views and activities. Moreover, the paper also gives important biographic facts which describe the founder of scientific pedagogy as a talented novice teacher at the Demidov Lyceum in Yaroslavl, where he won students’ genuine love and devotion. We analyse and comment on the outstanding educator’s main ideas related to the issues of native language teaching based on the principles of nationality (narodnost). In addition, drawing on Ushinsky’s wellknown works, we discuss the problems of creating universal schoolbooks for teaching the native language and speech and the basic requirements for the selection of didactic material for language courses with compulsory upbringing and developing potential. We focus attention on the critical issues of the anthropological and humanistic tradition in studying language and speech, the objectives of special comprehensive teacher training as well as the formation of teachers’ responsibility towards schoolchildren in education and upbringing.
Semantic opposition "vat"/"chalice" in M. M. Prishvin’s works (to the 150th anniversary of the birth)
Authors: Uryupin I. S.
Published: January 2023

The article considers the semantic opposition "vat"/"chalice", which has a strongly pronounced leitmotif character and is one of the constructive elements in the formation of the author’s meta- and supertext. Drawing on the material of M. M. Prishvin’s artistic, journalistic, documental and diary legacy, I reveal the motif-figurative universals, archetypes, constants which have significant mytho-suggestive potential. The paper aims to present a wide range of semantic connotations and formal and content variations of the "Chalice" and "Vat" concepts in M. M. Prishvin’s writings. Another objective is to establish the systemic relations between these concepts at different levels of text and meaning generation focusing on both syntagmatic and paradigmatic aspects. To achieve this goal, I employed structural-semantic, cognitive-functional, and historical-genetic methods of studying a literary text in the axiological paradigm of mo dern philology. The socio-cultural, religious-philosophical, and historical-literary context is involved in the analysis of the "chalice" and "vat" semantic images (eidos) to compare and contrast them. It actualises the semantic layers that make it possible to reconstruct M. M. Prishvin’s picture of the world and, more broadly, the author’s consciousness. The latter reflects not only the artist’s individual experience of cognising the micro- and macrocosm, but also the spiritual and world-view quest of the Russian intelligentsia that endured a series of terrible ordeals in the 20th century. Russian intellectuals immersed in the "vat" of passions and drank the chalice of suffering and atoning for sins.
B. A. Larin as researcher in bilingual lexicography of 16th-17th-сentury Muscovite Rus’ epoch
Authors: Nikitin O. V.
Published: January 2023

The contribution of B. A. Larin to the formation of a new lexicographic tradition in Russian science associated with the study of bilingual lexicons of the epoch of Moscovite Rus’ is analyzed. The events from the history of Soviet philology of the 1930s–1940s are commented on. The name of B. A. Larin is introduced into the context of contradictory phenomena in the public life of the country and the struggle against “cosmopolitans”. Attention is drawn to the originality of the scientist’s approach to the formulation and solution of the problem of understanding and introducing into research practice unique textual monuments compiled by foreigners. B. A. Larin’s painstaking work on deciphering and linguistic commenting of dictionary texts is noted. It is emphasized that for the first time in the philological tradition, Russian-foreign phrasebooks and dictionaries have become the object of attention of scientists as a linguistic and cultural phenomenon, which made it possible to give objective information about the features of everyday speech of different social strata of the population of Moscovite Rus’ in the 16th and 17th centuries. It is said about the prospects of this direction and subsequent developments in the study of dictionary bilingualism in domestic and foreign science. The role of the Larin school in the continuation of the historical and linguistic traditions of I. I. Sreznevsky, A. A. Shakhmatov, L. V. Shcherba is highlighted. The papers concludes on the originality of B. A. Larin’s ideas and their scientific value in modern lexicographic theory and practice.
Staff development policies cum funding as determinants of principal’s management efficiency in public secondary schools in Calabar zone of cross river state, Nigeria
Authors: Eniang-Esien Obia Ekpenyong *
Published: January 2023

The study aimed to examine Staff Development Policies cum Funding as determinants of Principals' Management Efficiency in public secondary schools in Calabar Zone of Cross River State, Nigeria. Two objectives, research questions, and hypotheses were formulated to guide the study and the study adopted the descriptive survey research design. The population of the study comprised all the five hundred and two (502) principals in public schools in Calabar education zone of Cross River State, Nigeria. To select the required respondents for the study, stratified random sampling techniques were used and the study utilize the Taro Yamane sample size determination to select a sample of 251 (10%) from the population as a sample. A researcher developed an instrument entitled "Staff Development Policies cum Funding and Principals Management Efficiency Questionnaire (SDPFPMEQ). The researcher developed an instrument that was validated by three (3) experts, one (1) in Measurement and Evaluation and two (2) in Educational Management. The reliability of the instrument was estimated with Cronbach Alpha reliability and the index ranges from .93 and .98, implying that the instrument was valid for data collection. The data were analysed with simple regression analysis and the findings revealed that; staff development policy, as well as the funding system, significantly predict Principals' Management Efficiency. It was recommended among others that adequate funds should be provided for the proper management of the departments.
Various analytical estimation techniques for quantification of Nifedipine: A review
Authors: Thangabalan Boovizhikannan  , Prasanth Naik Mude  , Srilekha Muthyala  , Soundarya Mude  , Gangaraju Kommu Vadde
Published: January 2023

Nifedipine, sold under the brand name Adalat and Procardia, among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. The review presented here systematizes various analytical and bio-analytical methods developed for Nifedipine alone and in combination with other drugs. It represents a comprehensive data of UV-Visible spectroscopy, HPTLC, HPLC and LC-MS methods reported by various scientists on Nifedipine.
Factors of Successful E-Petitions in Policy Making Process: A Scoping Review
Authors: Israwan Setyoko Paulus , Wahyuningrat Wahyuningrat , Kurniasih Denok
Published: January 2023

Efforts to continue to increase public participation in policymaking continue to be carried out as a step toward a more open government. Along with the popularity of online petitions (e-petitions) initiated by various lines of society, a systematic analysis was carried out to find out how successful an online petition (e-petitions) is as a public space in policy making. We try to provide a new perspective from a broader side of the previous partial research. This indicator of success is based on the original purpose for which the petition was published. As a result, there are three important things that are divided into two scopes of paths for achieving goals. First, the way of communication in which there is a linguistic approach is an important factor that influences how information from the petition is conveyed to the public and leads to the publicity of the petition. Second, the way of delivery is the basis for how the voice of the community is conveyed to policymakers, which is influenced by the political will of a region. Finally, media attention is a factor between the two scopes, which have dual roles as a “toa” to the public, and a messenger of policy. This review is expected to be a reference for initiators who propose policies from the community as well as a consideration for policymakers to actively involve the community's role in the policymaking process.
The association between Hb levels in placenta previa patients with apgar scores
Authors: Nurrahma Herlin Ajeng , Nur Intan Yulice Soraya , Meliala Andreanita , Narwidina Paramita
Published: January 2023

Hemoglobin (Hb) level is a biochemical indicator of the nutritional status of pregnant women, and a low Hb level reduces blood supply to the placenta, which influences the incidence of placenta previa. A placenta previa develops in the lower portion of the uterus, completely or partially expanding to cover the entire birth canal and the internal uterine ostium. The APGAR score is commonly used as a predictor of infant mortality and long-term disability and as an indicator of infant health at birth. The risk of maternal and infant mortality and morbidity increases in placenta previa patients with inadequate vascularization, which can be caused by low Hb levels. This study aimed to determine the relationship between Hb levels and APGAR scores in patients with placenta previa at Sultan Agung Islamic Hospital in Semarang. This analytic observation study is a cross-sectional analysis with purposive sampling method. From January 2017 to January 2018, all placenta previa patients hospitalized at Sultan Agung Hospital in Semarang were included in this study. In this study, we used subject data that met the criteria for inclusion. The p-value derived from the chi-square analysis is 0.041 (p< 0.05). A test of association was conducted. This test revealed that the OR was 11.5 (OR > 1). Low Hb levels (11 g/dl) could significantly increase the risk of a lower APGAR score at 5 min in patients with placenta previa who have a low Hb level.