bluuebunny/crossref_metadata_2025 huggingface dataset:
SUN-524 Patient with Pseudohypoparathyroidism Type 1B, Graves Disease, and False Positive HIV Screen- a Rare Presentation
Authors: Desai Viraj V , Kumar Pratima V
Published: May 2020

Background: Pseudohypoparathyroidism 1B (PHP1B) is a disorder that can lead to thyroid stimulating hormone (TSH) resistance and hypothyroidism, although it is rarely associated with thyrotoxicosis.

Clinical Case: A 25-year-old female with a history of PHP1B, seizures due to hypocalcemia, and family history of PHP1B in her three sisters and brother presented to our emergency room with a fever of 1030F and generalized malaise. Two months prior, she was seen at an outside hospital with palpitations and bulging of the left eye. There, she was diagnosed with hyperthyroidism, started on methimazole, and asked to continue levetiracetam and calcitriol upon discharge.

On our exam, she had tachycardia of 120 beats per minute, left eye proptosis, positive Chvostek sign, and a large goiter with bruit. Reflexes were 3+.

Laboratory evaluation revealed corrected serum calcium of 6.1 (8.5-10.5 mg/dL), TSH < 0.01 (0.34-5.60 mU/L), free T4 2.81 (0.60-1.60 ng/dL), free T3 13.0 (2.4-4.2 ng/dL), and iPTH 131 (12-88 pg/mL). ELISA testing for screening of HIV was positive. She was treated with IV calcium gluconate, methimazole, propranolol, and hydrocortisone. Her home doses of calcitriol and calcium were resumed. She was referred for total thyroidectomy as an outpatient once she became euthyroid. The confirmatory Western blot test for HIV was negative. It was determined that presence of thyroid stimulating immunoglobulin resulted in the false positive ELISA test.

Discussion: Hyperthyroidism with Graves disease seen in PHP has only very rarely been reported. (1) It has been postulated that abnormal electrolytes and elevated parathyroid hormone from PHP may lead to stimulation of the thyroid gland and perpetuate Graves disease symptoms. (2) Furthermore, the presentation of thyrotoxicosis despite TSH resistance in PHP indicates that there may be other mechanisms for TSH receptor antibodies to take effect in these patients which have not yet been determined. (3) Lastly, autoimmune diseases, including Graves disease, can cause a false-positive HIV ELISA as seen in our patient.

Conclusion: Although rare, thyrotoxicosis may present in patients with PHP1B. Additionally, it should be kept in mind that autoimmune diseases such as Graves disease can cause a false positive HIV ELISA, and follow-up Western blot testing should therefore be performed.

References:

(1) Gerhardt A, Hackenberg K. 2002. Pseudohypoparathyroidism and Graves’ disease: a rare combination of two endocrinological diseases. Exp Clin Endocrinol Diabetes. 110:245-247

(2) Morón-Díaz et al. 2019. A rare case of Graves’ disease in a patient with type 1B pseudohypoparathyroidism and associated TSH resistance. Endocrine Abstracts. 63:96

(3) Richard Prokesch. 2010. Navigating False Positive Testing. HIV Specialist (AAHIVS). 2:27
SUN-911 Immunotherapy Use in Adrenocortical Carcinoma with Encouraging Results- a Case Report
Authors: Madhavan Parvathy , Shichman Steven , Raj Nitya , Reidy-Lagunes Diane L , Malchoff Carl D
Published: May 2020

Adrenocortical carcinoma (ACC) is a rare cancer with a very poor prognosis with median survival of around 17 months. We present a patient with metastatic ACC in whom the response to PD1 inhibitor pembrolizumab has been promising.

Case report: A Caucasian female patient presented at the age of 19 y with weight gain, hypertension, moon facies, supraclavicular fullness and increased hair growth on her upper back. Serum potassium concentration was 2.6 mmol/l, cortisol was 46 mcg/dL (nl = 3-12mcg/dL), and plasma ACTH concentration was < 5 pg/ml (nl = 6-58pg/ml). CT abdomen revealed a 5.4 cm right adrenal mass. For ACTH-independent Cushing’s Syndrome, she underwent right adrenalectomy within 1 week of presentation. Pathology revealed a 6.5 cm ACC with negative margins, with sinusoidal invasion, but no vascular or capsular invasion. Mitosis rate was 15-20/HPF with atypical mitotic figures. Immunohistochemistry showed no loss of expression of mismatch repair gene products associated with microsatellite instability. She was unable to tolerate mitotane. Genetic analysis was negative for TP53 mutation, and she underwent radiation to the adrenal bed within 6 months following adrenalectomy. She remained without biochemical or structural evidence of disease recurrence until 2.5 years following adrenalectomy, when AM cortisol was 6 mcg/dL (nl < 1.8) after 1 mg and after 2 mg of dexamethasone the previous evening. CT scan of the pelvis, abdomen, and chest revealed 5 solid masses scattered within the lungs. The largest of these being 2.3 cm and 2 cm, and the other 3 being approximately 1 cm. Fine needle aspiration biopsy of the lung lesion revealed ACC metastases. Immunotherapy with pembrolizumab 200 mg every 3 weeks was initiated and continued for 2 years, with a side effect being grade 1 diarrhea. At 1 year after initiating pembrolizumab, she developed primary adrenal insufficiency that is being treated with 0.1 mg/d of fludrocortisone and low dose glucocorticoid replacement (hydrocortisone: 10mg in the morning and 5 mg in the evening), to avoid immune suppression. Pulmonary nodules decreased in size to 6 mm over the 2 years of pembrolizumab therapy and remained stable in size 1 year following completion of pembrolizumab therapy at which time the early morning serum cortisol concentration remained undetectable with a plasma ACTH concentration of 1177 pg/ml (nl = 6-50 pg/ml). In summary, this patient with ACC with normal mismatch repair gene expression demonstrated both structural and biochemical responses to 2 years of pembrolizumab therapy. The major side effect has been primary adrenal insufficiency. The biochemical and structural responses have been durable for 1 year after completion of pembrolizumab therapy.

Conclusion: This patient with microsatellite stable ACC has had a 36-month response to pembrolizumab.
Informed Consent in Patients With Frailty Syndrome
Authors: Silbert Brendan S. , Scott David A.
Published: May 2020

Frailty is present in more than 30% of individuals older than 65 years of age presenting for anesthesia and surgery, and poses a number of unique issues in the informed consent process. Much attention has been directed at the increased incidence of poor outcomes in these individuals, including postoperative mortality, complications, and prolonged length of stay. These material risks are not generally factored into conventional risk predictors, so it is likely that individuals with frailty are never fully informed of the true risk for procedures undertaken in the hospital setting. While the term “frailty” has the advantage of alerting to risk and allowing appropriate care and interventions, the term has the social disadvantage of encouraging objectivity to ageism. This may encourage paternalistic behavior from carers and family encroaching on self-determination and, in extreme cases, manifesting as coercion and compromising autonomy. There is a high prevalence of neurocognitive disorder in frail elderly patients, and care must be taken to identify those without capacity to provide informed consent; equally important is to not exclude those with capacity from providing consent. Obtaining consent for research adds an extra onus to that of clinical consent. The informed consent process in the frail elderly poses unique challenges to the busy clinical anesthesiologist. At the very least, an increased time commitment should be recognized. The gap between theoretical goals and actual practice of informed consent should be acknowledged.
Frailty in Critical Care Medicine: A Review
Authors: De Biasio Justin C. , Mittel Aaron M. , Mueller Ariel L. , Ferrante Lauren E. , Kim Dae H. , Shaefi Shahzad
Published: May 2020

Traditional approaches to clinical risk assessment utilize age as a marker of increased vulnerability to stress. Relatively recent advancements in the study of aging have led to the concept of the frailty syndrome, which represents a multidimensional state of depleted physiologic and psychosocial reserve and clinical vulnerability that is related to but variably present with advancing age. The frailty syndrome is now a well-established clinical entity that serves as both a guide for clinical intervention and a predictor of poor outcomes in the primary and acute care settings. The biological aspects of the syndrome broadly represent a network of interrelated perturbations involving the age-related accumulation of molecular, cellular, and tissue damage that leads to multisystem dysregulation, functional decline, and disproportionately poor response to physiologic stress. Given the complexity of the underlying biologic processes, several well-validated approaches to define frailty clinically have been developed, each with distinct and reasonable considerations. Stemming from this background, the past several years have seen a number of observational studies conducted in intensive care units that have established that the determination of frailty is both feasible and prognostically useful in the critical care setting. Specifically, frailty as determined by several different frailty measurement tools appears associated with mortality, increased health care utilization, and disability, and has the potential to improve risk stratification of intensive care patients. While substantial variability in the implementation of frailty measurement likely limits the generalizability of specific findings, the overall prognostic trends may offer some assistance in guiding management decisions with patients and their families. Although no trials have assessed interventions to improve the outcomes of critically ill older people living with frailty, the particular vulnerability of this population offers a promising target for intervention in the future.
Palliative Care and End-of-Life Considerations for the Frail Patient
Authors: Crooms Rita C. , Gelfman Laura P.
Published: May 2020

Patients with frailty experience substantial physical and emotional distress related to their condition and face increased morbidity and mortality compared with their nonfrail peers. Palliative care is an interdisciplinary medical specialty focused on improving quality of life for patients with serious illness, including those with frailty, throughout their disease course. Anesthesiology providers will frequently encounter frail patients in the perioperative period and in the intensive care unit (ICU) and can contribute to improving the quality of life for these patients through the provision of palliative care. We highlight the opportunities to incorporate primary palliative care, including basic symptom management and straightforward goals-of-care discussions, provided by the primary clinicians, and when necessary, timely consultation by a specialty palliative care team to assist with complex symptom management and goals-of-care discussions in the face of team and/or family conflict. In this review, we apply the principles of palliative care to patients with frailty and synthesize the evidence regarding methods to integrate palliative care into the perioperative and ICU settings.
Role of Micro-RNA for Pain After Surgery: Narrative Review of Animal and Human Studies
Authors: Cata Juan P. , Gorur Aysegul , Yuan Xiaoyi , Berg Nathaniel K. , Sood Anil K. , Eltzschig Holger K.
Published: May 2020

One of the most prevalent symptoms after major surgery is pain. When postoperative pain treatment is unsatisfactory, it can lead to poor surgical recovery, decreased quality of life, and increased health care costs. Current analgesics, single or in combination, have limited efficacy due to low potency, limited duration of action, toxicities, and risk of addiction. The lack of nonaddictive strong analgesics along with the over prescription of opioids has led to an opioid epidemic in the United States. Therefore, there is an urgent need for the development of newer analgesics. Microribonucleic acids (miRNAs) are small noncoding RNA molecules that modulate protein synthesis in neurons and supporting cells (glia, leukocytes, and Schwann cells). The literature indicates that miRNA regulation is important in nociception. Here, we summarize the current evidence on the role of miRNAs on mechanisms involved in incisional, inflammatory, neuropathic, and cancer pain. We also discuss the role of modulating miRNA functions as potential therapeutic targets for analgesic use and opioid tolerance. Finally, we propose how the delivery of analog miRNAs (mimic-miRNAs or antago-miRNAs) could be introduced into clinical practice to provide analgesia in the perioperative period.
Critical Illness and the Frailty Syndrome: Mechanisms and Potential Therapeutic Targets
Authors: Paul Jonathan A. , Whittington Robert A. , Baldwin Matthew R.
Published: May 2020

Frailty is a syndrome characterized by decreased reserves across multiple physiologic systems resulting in functional limitations and vulnerability to new stressors. Physical frailty develops over years in community-dwelling older adults but presents or worsens within days in the intensive care unit (ICU) because common mechanisms governing age-related physical frailty are often exacerbated by critical illness. The hallmark of physical frailty is a combined loss of muscle mass, force, and endurance. About one-third of ICU patients have frailty before hospitalization, which increases their risk for both short- and long-term disability and mortality. While there are several valid ways to measure clinical frailty in patients before or after an ICU admission, the mechanistic underpinnings of frailty in critically ill patients and ICU survivors have not been thoroughly investigated. Furthermore, therapeutic interventions to treat frailty during and after time in the ICU are lacking. In this narrative review, we examine studies that identify potential biological mechanisms underlying the development and propagation of physical frailty in both aging and critical illness (eg, inflammation, mitochondrial myopathy, and neuroendocrinopathy). We discuss specific aspects of these frailty mechanisms in older adults, critically ill patients, and ICU survivors that may represent therapeutic targets. Consistent with complexity underlying frailty, this syndrome is unlikely to result from an excess of a single harmful mediator or deficit of a single protective mediator. Rather, frailty occurs in the presence of an incompletely understood state of multisystem dysregulation. We further describe knowledge gaps that warrant clinical and translational research in frailty and critical care with an overall goal of developing effective frailty treatments in critically ill patients and ICU survivors.
The Turn to Logic and the Transformation of an Ancient Quarrel
Authors: Boyce Kristin
Published: May 2020

The development of an analytic tradition in philosophy is bound up with a newly intensified interest in logic, and Frege’s development of a new form of logical notation — an early form of what is now called predicate logic — is one of the conditions that made that tradition possible. At the same time, the development of analytic philosophy is also tied to a turn away from what had until that time been a natural and often mutually beneficial exchange with poetry, drama, and fiction. It is easy to assume that the turn away from literature is a necessary consequence of the turn to logic. This essay argues that in fact there are good reasons to think that if we follow the turn to formal logic through, it instead pushes philosophy back into a transformed and perhaps deeper kind of conversation with literature. The terms that organize this renewed conversation are those of a shared preoccupation not with certain ideas or content but with the power of form. The upshot is that the turn to formal logic returns philosophy to a transformed version of the “ancient quarrel” with which it began.
Reading Virginia Woolf Logically
Authors: Quigley Megan
Published: May 2020

This article argues for a “resolute reading” of Virginia Woolf’s The Voyage Out, akin to Cora Diamond and James Conant’s reading of Ludwig Wittgenstein’s Tractatus Logico-Philosophicus. The resolute approach to the Tractatus contends that we should embrace Wittgenstein’s assertion that the Tractatus is finally nonsense. Accordingly, the Tractatus acts as a kind of therapy, enabling us to dispense with certain types of philosophical, linguistic, and analytical claims. I argue that Woolf’s The Voyage Out takes a similar approach to the nineteenth-century novel, fully investing in the conventions of the bildungsroman and the marriage plot only to ruthlessly dispense with them. Both works use a particular kind of modernist therapeutic pedagogy reliant on logic and form.
Localness in Climate Change
Authors: Shepherd Theodore G. , Sobel Adam H.
Published: May 2020

Climate change is a global problem, yet it is experienced at the local scale, in ways that are both place-specific and specific to the accidents of weather history. This article takes the dichotomy between the global and the local as a starting point to develop a critique of the normative approach within climate science, which is global in various ways and thereby fails to bring meaning to the local. The article discusses the ethical choices implicit in the current paradigm of climate prediction, how irreducible uncertainty at the local scale can be managed by suitable reframing of the scientific questions, and some particular epistemic considerations that apply to climate change in the global South. The article argues for an elevation of the narrative and for a demotion of the probabilistic from its place of privilege in the construction and communication of our understanding of global warming and its local consequences.
Information Technology in Auditing
Authors: Kazakova Nataliya , Brovkina N.
Published: May 2020

Th e article is devoted to methodological approaches to testing competencies in the fi eld of information technology, which are new in the qualifi cation exam for auditors of the Russian Federation, which entered into force on March 31, 2020. In this regard, the kinds and types of test tasks for the use of information technologies at the fi rst stage of a new exam module «Fundamentals of Auditing» are considered, examples of correct answers are given, links to sources are given for preparing to solve such tests.
Decentralized Payment Systems and Their Interaction with the Current Tax System
Authors: Soltakhanov A.
Published: May 2020

Th is article discusses decentralized payment systems that are becoming more widespread in the global economy in the context of globalization and digitalization. Special attention is paid to the taxation of operations of decentralized payment systems in domestic and foreign practice.
Diagnostics and correction of vestibular, autonomic and vascular dysfunctions on the background of degenerative changes in the cervical spin
Authors: Mashchenko S. S.
Published: May 2020

Studies in 82 patients were aimed at optimizing the diagnosis and treatment of vestibular dysfunctions with vegetative-vascular disorders during degenerative changes in the cervical spine.The main symptoms of vestibulopathy were dizziness as well as their provoking and related causes. Obtained objective state data of the vestibular analyzer using the integrative index of ataxia, the state of autonomic characteristics, data of the psychoemotional and cognitive sphere. The author's method of treating such conditions using a complex of vegetotropic, vascular, nootropic drugs, as well as intranasal electrophoresis, was used. Positive results were obtained for this type of therapy for vestibulopathy and autonomic vascular disorders.
Your Hometown Matters: Popularity-Difference Bias in Online Reputation Platforms
Authors: Kokkodis Marios , Lappas Theodoros
Published: May 2020

We study a new source of bias in online review platforms that originates from the popularity difference between the traveling reviewer’s hometown and destination.
Outsourcing Through Purchase Contracts and Firm Capital Structure
Authors: Moon S. Katie , Phillips Gordon M.
Published: May 2020

We examine firm and industry characteristics associated with outsourcing and the relation between outsourcing and capital structure using a unique database of outsourcing purchase contracts. We find that highly valued, profitable firms with high-value added per employee and suppliers farther away with higher competition are more likely to outsource using purchase contracts. In addition, we document that firms that operate in industries with more severe import penetration and fewer fixed assets are more likely to outsource using purchase contracts. Examining the outside purchase contract and leverage decisions, we find that the outsourcing decision is associated with less leverage. Our results are consistent with firms that choose to use purchase contracts using less leverage to mitigate the potential loss of relation-specific investments of contracting parties that can occur with financial distress or bankruptcy.

This paper was accepted by Gustavo Manso, finance.
AUTORIA DE MULHERES NO CINEMA DE FICÇÃO CIENTÍFICA BRASILEIRO: OUTRAS PERSPECTIVAS PARA O FEMINISMO CONTEMPORÂNEO
Authors: Silva Carolina De Oliveira
Published: May 2020

Este artigo pretende desenvolver uma reflexão acerca da perspectiva de cineastas mulheres no cinema brasileiro a partir de um recorte que abarque a cinematografia de ficção científica nacional. Ao abordar o filme Kenoma (1998) de Eliane Caffé e Acquaria (2003) de Flávia Moraes, essa pesquisa pretende questionar: quais as contribuições do gênero para o desenvolvimento de um olhar feminino? Quais as perspectivas para uma FC brasileira em meio as prerrogativas do feminismo contemporâneo? Ao analisar os meios de representação para as personagens femininas, a utilização do corpo como um dos meios de contestação e as temáticas ambientais – a falta de água e o modo de vida primitivo – abordados no filme, a hipótese é de que, mesmo confirmando a escassez quanto a autoria, a própria FC científica brasileira resguarda aproximações muito contundentes com a história das mulheres no país, assim como, possui muito a dizer sobre uma alternativa cada vez mais decisiva em nossa forma de convívio social.
OS QUADRINHOS DE FICÇÃO CIENTÍFICA BRASILEIROS DOS ÚLTIMOS ANOS
Authors: Zeni Lielson
Published: May 2020

Resumo: Como é o cenário atual de ficção científica brasileira, escrita em português, nas histórias em quadrinhos? Em busca dessa resposta foi procurado quais foram os lançamentos dentro dessa área da ficção especulativa nos anos de 2017, 2018 e em parte de 2019. Para isso, foram listadas as obras lançadas no Brasil no período, levando em conta as particularidades do processo de publicação de histórias em quadrinhos em nosso país. Este artigo se aproxima mais de um relatório de apresentação de resultados e de dados do que propriamente de um texto que propõe discussões baseadas em argumentações teóricas e análises de caso. A ideia é que os dados apresentados aqui possam ser usados por outros pesquisadores em seus trabalhos.
A MULHER MAIS BELA DO MUNDO: ALTERIDADE E FICÇÃO CIENTÍFICA
Authors: Gama Vítor Castelões
Published: May 2020

Este artigo discute sobre os dilemas da ficção científica brasileira e responde a crítica de despolitização do gênero tendo como base o conto A mulher mais bela do mundo, do escritor Roberto de Sousa Causo, e a noção de antropologia reversa, de Roy Wagner. A mulher mais bela do mundo ressignifica as tradicionais obras de “primeiro contato”, nas quais o alienígena é frequentemente usado como alteridade radical que, por contraposição, permite pensar sobre nós mesmos. Neste conto, os alienígenas também utilizam os humanos para demarcar os limites entre o eu/outro. O conflito central ocorre em uma exposição fotográfica que nomeia a obra. Por fim, aplicamos o referencial teórico da antropologia reversa por esta implicar um posicionamento ativo de todas as partes envolvidas. Esta perspectiva é mais condizente com a posição da ficção científica brasileira e interessante para pesquisas posteriores que envolvam a antropologia.
MARGINAIS DE UM PASSADO FUTURISTA: O NASCIMENTO DO GÊNERO STEAMPUNK NOS EUA E SUA PRIMEIRA RECEPÇÃO NO BRASIL
Authors: Tavares Enéias
Published: May 2020

No decorrer da década de 1980, muitos escritores de ficção científica e fantasia reinterpretaram o espírito “punk” da década anterior, enfatizando cenários insólitos, realidades alternativas e fantasias alocadas no passado ou no futuro. Um elemento central a essas histórias era a presença de heróis marginais, páreas sociais e minorias étnicas que pouco espaço ganharam em exemplares do gênero nas décadas anteriores, uma vez que seus respectivos autores ainda preferiam heróis caucasianos idealizados, vítimas femininas em perigo e ameaças malignas, de preferência de origem intergaláctica ou oriental.  Na contracorrente dessa produção, três autores estadunidenses passaram a produzir histórias nas quais a revisão fantástica do passado preconizou problemas sociais e reflexões políticas pertinentes ao seus tempos. Neste ensaio, analisarei três romances considerados fundadores do gênero, bem como seu impacto nos anos seguintes tanto sobre a produção steampunk como também no cenário literário brasileiro.
NO PAÍS DOS VAPORISTES: O CONCEITO DE “RECICLAGEM” DE GIRARDOT E MÉRESTE E O STEAMPUNK À FRANCESA
Authors: Matangrano Bruno Anselmi
Published: May 2020

DIÁLOGO
High-resolution, ultrafast, wide-field retinal eye-tracking for enhanced quantification of fixational and saccadic motion
Authors: Bartuzel Maciej M. , Wróbel Krystian , Tamborski Szymon , Meina Michał , Nowakowski Maciej , Dalasiński Krzysztof , Szkulmowska Anna , Szkulmowski Maciej
Published: May 2020

We introduce a novel, noninvasive retinal eye-tracking system capable of detecting eye displacements with an angular resolution of 0.039 arcmin and a maximum velocity of 300°/s across an 8° span. Our system is designed based on a confocal retinal imaging module similar to a scanning laser ophthalmoscope. It utilizes a 2D MEMS scanner ensuring high image frame acquisition frequencies up to 1.24 kHz. In contrast with leading eye-tracking technology, we measure the eye displacements via the collection of the observed spatial excursions for all the times corresponding a full acquisition cycle, thus obviating the need for both a baseline reference frame and absolute spatial calibration. Using this approach, we demonstrate the precise measurement of eye movements with magnitudes exceeding the spatial extent of a single frame, which is not possible using existing image-based retinal trackers. We describe our retinal tracker, tracking algorithms and assess the performance of our system by using programmed artificial eye movements. We also demonstrate the clinical capabilities of our system with in vivo subjects by detecting microsaccades with angular extents as small as 0.028°. The rich kinematic ocular data provided by our system with its exquisite degree of accuracy and extended dynamic range opens new and exciting avenues in retinal imaging and clinical neuroscience. Several subtle features of ocular motion such as saccadic dysfunction, fixation instability and abnormal smooth pursuit can be readily extracted and inferred from the measured retinal trajectories thus offering a promising tool for identifying biomarkers of neurodegenerative diseases associated with these ocular symptoms.
Perfect anomalous reflection using a compound metallic metagrating
Authors: Rahmanzadeh Mahdi , Khavasi Amin
Published: May 2020

Metagrating is a new concept for wavefront manipulation that, unlike phase gradient metasurfaces, does not suffer from low efficiency and also has a less complicated fabrication process. In this paper, a compound metallic grating (a periodic metallic structure with more than one slit in each period) is proposed for anomalous reflection. We propose an analytical method for analyzing the electromagnetic response of this grating. Closed-form and analytical expressions are presented for the reflection coefficients of zeroth diffracted order and also higher diffracted orders. The proposed method is verified against full-wave simulations and the results are in excellent agreement. Thanks to the geometrical asymmetry of compound metallic grating, it can be used for designing anomalous reflection at the normal incidence. Given analytical expressions for reflection coefficients, we design a perfect anomalous reflector for a TM polarized plane wave via transferring all the incident power to ( − 1) diffraction order . The structure designed in this study has an unprecedented near-to-unitary efficiency of 99.9%. Finally, a multi-element compound metallic grating is proposed for reflecting the normal incidence to angles of below 30°, which is a challenging accomplishment. This excellent performance of compound metallic grating shows its high potential for microwave and terahertz wavefront manipulation applications.
Agroecologia como estratégia política, produtiva e ambiental para a defesa de uma reforma agrária popular
Authors: Silva Rafael Pereira , Conceição José Rubens Laureano da , Betanho Cristiane
Published: May 2020

Pode o movimento e a prática agroecológica se apresentar como um projeto de desenvolvimento, como estratégia política, produtiva e ambiental que, ao mesmo tempo, se contraponha à destruição ambiental e social promovida pelo latifúndio e evidencie a importância de uma reforma agrária popular? Para refletir sobre essa questão, foi proposta uma Roda de Conversa durante a V Jornada Universitária em Defesa da Reforma Agrária (JURA), que aconteceu entre 8 e 10 de maio de 2019, na Universidade Federal de Uberlândia. Os participantes entenderam que a agroecologia, ao se contrapor ao modelo vigente, supera a ideia de ser somente uma alternativa para produzir alimentos, e busca a transformação da sociedade de forma a garantir melhores condições de vida às pessoas do campo e da cidade. Nesse processo, a reforma agrária pode ser conhecida pelo seu real lado, a partir do reconhecimento dos trabalhadores que lutam pelo direito a terra, por um meio ambiente preservado e relações sociais justas para todos, sem as mistificações da mídia hegemônica.
Educação, comunicação e mobilização social, estratégias de promoção da saúde no monitoramento de vetores em assentamentos rurais
Authors: Oliveira João Carlos de , Bonassi Vinícius , Melo Guilherme Macedo de
Published: May 2020

Este trabalho é resultado de uma Roda de Conversa, realizada durante a V Jornada Universitária em Defesa da Reforma Agrária, fruto das parcerias, no monitoramento de vetores, entre a Escola Técnica de Saúde da Universidade Federal de Uberlândia, o Instituto Federal de Educação, Ciência e Tecnologia - Campus Uberlândia e Associação de Recicladores e Catadores Autônomos. A degradação ambiental tem disseminado arbovírus, entre eles os Aedes (Aegypti e albopictus) e o Culex e suas arboviroses. Nas áreas urbanas, temos a Dengue, Chikungunya, Febre do Nilo Ocidental, Zika, Rocio e Mayaro; em ambientes rurais (e até urbanos), e alguns casos silvestres, temos os flebotomíneos, popularmente chamados de “mosquito palha” ou “cangalhinha” responsáveis pela Leishmaniose Visceral e/ou Leishmaniose Tegumentar e os Haemagogus e Sabethes, responsáveis pela Febre Amarela Silvestre. A Roda de Conversa ocorreu na concepção e construção dialógica sobre “O que faço, o que sei e o que precisamos saber de saúde ambiental em relação aos vetores”, considerando os estilos e modos de vidas das pessoas. Por isso, a importância de um processo educativo, da comunicação e mobilização social, aqui denominados de “Educomunicação e Educação Popular em Saúde”, como forma de estabelecer ambientes saudáveis, enquanto estratégias da promoção da saúde.
Reflexões sobre a territorialização LGBT na luta pela terra no Brasil
Authors: Chelotti Marcelo Cervo , Santos Samuel  Lucas Silva Gomes , Fileto Vinícius Nunes
Published: May 2020

A Jornada Universitária pela Reforma Agrária (JURA) da Universidade Federal de Uberlândia acontece tradicionalmente através de uma agenda nacional de eventos com esse fim. A intenção deste texto é trazer as reflexões sobre a territorialização do movimento de lésbicas, gays, bissexuais, travestis e transexuais (LGBT) dentro dos movimentos de luta pela terra no Brasil, especialmente os ligados à Via Campesina, tratados em uma roda de conversa promovida por estudantes do tema para os alunos e integrantes dos movimentos sociais da JURA-UFU. Entendendo que a inserção dessa pauta é um processo que está ocorrendo em escala nacional, o objetivo da roda é levantar questões que são recorrentemente invisibilizadas como a pauta das sexualidades camponesas e a vivência LGBT dentro de acampamentos e assentamentos da Reforma Agrária no Brasil.
Reforma agrária em questão (Banco de Dados da Luta pela Terra – DATALUTA)
Authors: Cleps Junior João , Victor Fabiana Borges , Boaventura Júnior Cairo Roberto , Costa Karen Regina Silva
Published: May 2020

Este relato apresenta as experiências resultantes da proposição e do desenvolvimento de uma roda de conversa sobre a realidade agrária brasileira na perspectiva do Banco de Dados da Luta pela Terra (DATALUTA). A intervenção integrou a V Jornada Universitária em Defesa da Reforma Agrária, realizada na Universidade Federal de Uberlândia em maio de 2019, e se configurou como um importante instrumento metodológico em que foram expostos os conhecimentos em um momento de construção coletiva de reflexões a partir das vivências e saberes dos participantes.
Enhancing Wool Fabric Easy Care Properties by Shape Memory Polyurethane Finishing
Authors: Memiş Nazife Korkmaz , Kaplan Sibel
Published: May 2020

Wool fabrics having temperature sensitive shape memory effect were fabricated by using a shape memory polyurethane (SMPU) treatment. The contribution of SMPU treatment on bagging recovery and felting shrinkage, crucial properties for end use performance, was investigated by a test procedure including hot water conditions simulating laundry of garments according to the Woolmark TM31 standard. Chemical and morphological analyses, bending rigidity, and tear strength tests were also carried out to determine the effects of SMPU treatment on performance properties. SMPU treatment significantly increased weight and rigidity of fabrics. Most notably, SMPU treated wool fabric exhibited excellent temperature sensitive bagging recovery stimulated by a washing procedure. Also, anti-felting and weight loss performances were quite high compared to raw and commercial polyurethane-treated fabrics.
A Novel Durable and Water-Soluble N-Halamine Precursor for Antibacterial Cellulose Fabrics
Authors: Xu Denghui , Ma Xingbo , Zhu Ping , Jiang Zhiming
Published: May 2020

A novel, water-soluble N-halamine precursor based on s-triazine (2-(aminoethanesulfonic sodium salt)-4-(4-imino-2,2,6,6-tetramethylpiperidine)-6-monochloro-1,3,5-triazine, ATDT) was synthesized and characterized by FT-IR and 1 H-NMR. The cotton fabrics were functionalized with ATDT through the traditional pad-dry-cure method, and optimal conditions were successfully obtained by measuring the active chlorine content. The antibacterial activity of ATDT-coated cotton fabrics was investigated against Staphylococcus aureus and Escherichia coli O157:H7. As a result, 100% of bacteria could be inactivated within a brief contact time. Cell viability was also determined and the results showed that ATDT-modified cotton fabrics had good cytocompatibility to mammalian cells. In addition, the preparation process had little effect on the tensile strength and whiteness of cotton fabrics, although the air permeability showed a slight decrease. The chlorinated ATDT-coated fabrics showed excellent stability against storage and washing.
Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations
Authors: Del Arco Alberto , Park Junchol , Moghaddam Bita
Published: May 2020

Brain networks that mediate motivated behavior in the context of aversive and rewarding experiences involve the prefrontal cortex (PFC) and ventral tegmental area (VTA). Neurons in both regions are activated by stress and reward, and by learned cues that predict aversive or appetitive outcomes. Recent studies have proposed that separate neuronal populations and circuits in these regions encode learned aversive versus appetitive contexts. But how about the actual experience? Do the same or different PFC and VTA neurons encode unanticipated aversive and appetitive experiences? To address this, we recorded unit activity and local field potentials (LFPs) in the dorsomedial PFC (dmPFC) and VTA of male rats as they were exposed, in the same recording session, to reward (sucrose) or stress (tail pinch) spaced 1 h apart. As expected, experience-specific neuronal responses were observed. Approximately 15–25% of single units in each region responded by excitation or inhibition to either stress or reward, and only stress increased LFP theta oscillation power in both regions and coherence between regions. But the largest number of responses (29% dmPFC and 30% VTA units) involved dual-valence neurons that responded to both stress and reward exposure. Moreover, the temporal profile of neuronal population activity in dmPFC and VTA as assessed by principal component analysis (PCA) were similar during both types of experiences. These results reveal that aversive and rewarding experiences engage overlapping neuronal populations in the dmPFC and the VTA. These populations may provide a locus of vulnerability for stress-related disorders, which are often associated with anhedonia.
Pathways of megaherbivore rewilding transitions: typologies from an Andean gradient
Authors: Grau H. Ricardo , Aráoz Ezequiel , Navarro Carlos J. , Nanni A. Sofía , Malizia Agustina
Published: May 2020

In most of the planet, large herbivore communities have been replaced by livestock, but this process is reversing in many places. Here, we outline and review the pathways of “megaherbivore rewilding transitions” in three social-ecological-systems of subtropical Argentina. In the extensive arid high-elevation Puna plateau we observed a “rapid rewilding pathway” where the reduction of livestock was accompanied by the recovery of native camelid populations from near extinction in a few decades. In the forest-grassland ecotone, decreasing livestock favored higher fire frequency, probably limiting the speed of native herbivore recovery in an “increasing fire pathway”. In lowland montane forests, the recovery of native herbivore communities appears to be lagged by fragmentation, local extinctions and human pressure, representing a case of “connectivity-limited rewilding”. These typologies exemplify the complexity of outcomes resulting from livestock diminishing density, and provide a framework to understand and optimize processes of large herbivore rewilding according to different social-ecological contexts.
Penguatan Konsep Pemrograman Berorientasi Objek Siswa Kelas XI RPL SMKN 2 Semarang
Authors: Ningrum Seffy Kusuma , Djuniadi Djuniadi
Published: May 2020

Tujuan dari studi ini adalah untuk meningkatkan keterampilan pemrograman berorientasi objek siswa kelas XI RPL SMKN 2 Semarang. Metode yang digunakan adalah studi perbandingan dengan one sample t test. Penelitian ini mempunyai lima tahapan. Tahap pertama melakukan penilaian awal. Tahap kedua melakukan pembelajaran dengan belajar kelompok dan presentasi. Tahap ketiga memberi penugasan. Tahap keempat memberi penguatan konsep alur dan logika pemrograman. Tahap kelima, menyelesaikan kasus pemrograman berorientasi objek. Hasil analisis sebelum perlakuan didapatkan rata-rata nilai 70,74 dengan thitung = 0,340 serta nilai sig = 0,736 â‰¥ 0,05 sehingga dapat dikatakan bahwa rataâ€“rata nilai siswa = 70. Kalau dilihat dari proporsinya, sampel dengan nilai <= 70 sebanyak 10 siswa dan sampel dengan nilai > 70 sebanyak 24 siswa. Hasil analisis setelah perlakuan diskusi kelompok dan presentasi didapatkan rata-rata nilai 84,56 dengan thitung = 17,047 serta nilai sig = 0,00 sehingga dapat dikatakan bahwa rataâ€“rata nilai siswa >70. Sedangkan proporsinya, sampel dengan nilai >70  adalah seluruh siswa. Hasil analisis setelah perlakukan penguatan konsep pemrograman didapatkan rata-rata nilai 88,18 dengan thitung = 21,424 serta nilai sig = 0,00 sehingga dapat dikatakan bahwa rataâ€“rata nilai siswa >70. Kalau dilihat dari proporsinya sampel dengan nilai >70 adalah seluruh siswa.
Perancangan Sistem Monitoring Suhu Ruangan Fermentasi Bawang Hitam Berbasis Mikrokontroler
Authors: Murtadlo Muhammad Aliyul , Wibowo Dimas Wahyu , Rokhman Syaiful , Amirulloh Reffan Pandu , Floresko Septian Caesar , Alhamda Syahdanny
Published: May 2020

Garlic includes a very beneficial plant in processing, both to serve as a spice of cooking or medicine. Garlic can also be processed by fermentation that will produce the Black onion. The fermentation process to produce black onion involves the temperature and humidity in which the consistency must be thoroughly controlled. With the above problem can be done by design of fermentation tool to produce black onion by utilizing information technology. In this tool system control is done by a Wemos D1 R2 microcontroller that has an input in the form of a DHT11 sensor, this sensor will detect the temperature and humidity that are in the fermentation tool. From the results of temperature information and humidity will be displayed in the Mobile application. The Monitoring tool also includes a WiFi module to transmit data on the temperature and humidity conditions of the mobile application.
Efecto del programa FIFA 11+ en la flexibilidad de los cadetes de V nivel de la Facultad de Educación Física Militar de la Escuela Militar General José María Córdova
Authors: Camacho Arcila Brayan , Colmenares Murcia Iván , Reyes Forero Carlos , Guerrero Osma Omar Danilo
Published: May 2020

El objetivo de este estudio fue analizar el efecto del programa de calentamiento FIFA 11+ en los cadetes de V nivel de la Facultad de Educación Física Militar (FEFM) de la Escuela Militar de Cadetes (ESMIC) y su relación con la flexibilidad, a través de un estudio experimental descriptivo tipo ensayo clínico, realizando la evaluación por medio de test Sit and Reach con cajón, seguidamente se implementó el programa de calentamiento FIFA 11+ al grupo experimental durante 10 semanas, 3 veces por semana. Los datos estadísticos fueron analizados por medio de modelo ANOVA Factorial. Los resultados indican que en el grupo experimental mejoró 67.9% comparado con 8.2% con el grupo control por tanto se llegó a la conclusión que el programa de calentamiento FIFA 11+ es efectivo para mejorar la flexibilidad en los cadetes de v nivel de la FEFM de la ESMIC.
Cuantificación del entrenamiento funcional mediante la valoración del esfuerzo percibido en sujetos físicamente activos
Authors: Bustos-Viviescas Brian Johan , Arévalo Contreras Daniel Eduardo , Acevedo Mindiola Andrés Alonso , Castellanos Jiménez John Steven
Published: May 2020

El propósito del estudio fue determinar la relación entre la valoración del esfuerzo percibido en la sesión (EPES) y el índice de Edwards (IE) para cuantificar la carga interna basado en la frecuencia cardiaca en el entrenamiento funcional de alta intensidad con sujetos físicamente activos. Estudio descriptivo de tipo correlacional con una muestra a conveniencia conformada por 16 hombres y 7 mujeres. En la valoración de la FCmáx se utilizó el Test de Course-Navette y dos días después se realizó el WOD Karen donde cada participante contaba con un pulsómetro Polar H7 y se recolectaba la escala de percepción subjetiva de la sesión (0-10), a partir de estos datos se calculó el IE. En el software PSPP (p-valor de 0.05) se llevó a cabo el análisis estadístico donde se utilizó un coeficiente correlacional de Spearman para relacionar la EPES y el IE. La relación entre la escala recolectada en los diferentes fragmentos de tiempo post-ejercicio y el IE fue positiva y muy significativa (r = 0.6-0.8; p < 0.01). En conclusión, la EPES es un método viable, económico y de fácil aplicación para cuantificar la carga interna en el entrenamiento funcional de alta intensidad con sujetos físicamente activos.
Análisis del sobrepeso, obesidad, actividad física y autoestima de la niñez en el área metropolitana de la región educativa panameña
Authors: Ambulo Arosemena Graciela , González Salina Margarita , Montenegro Raúl , Brooks Yileika , Bonilla Margarita , Camarena Melissa , Moreno Yoselyn
Published: May 2020

Los altos niveles de sobrepeso y obesidad que producen diabetes, hipertensión u otras enfermedades crónicas son un problema de salud pública, que inicia desde la infancia hasta alcanzar la edad adulta y alteran, directamente, la calidad de vida de la persona. El propósito de este estudio es determinar los niveles de sobrepeso y obesidad, los niveles de actividad física y de autoestima de escolares de 9 a 13 de edad, en 13 centros educativos de la ciudad de Panamá centro. Se evaluaron un total de 748 estudiantes. Las variables se midieron por medio por medio del tallímetro y la pesa para calcular el índice de masa corporal, el cuestionario PAQ-C para medir la actividad física y el LAWSEQ para medir la autoestima de los niños y las niñas. En la población estudiada, se mostró un 17 % de estudiantes con sobrepeso, un 13 % con obesidad; un 70.05 % con actividad física moderada y un 25.67 % con bajos niveles de actividad física. En cuanto a la autoestima, se evidenció un 50.5 % con autoestima promedio y un 44 % con autoestima baja. En conclusión, el análisis de los resultados indica una mayor prevalencia de obesidad en las niñas, y un mayor nivel de actividad física en los niños; en el caso de la autoestima, la edad juega un papel importante en la percepción personal, especialmente en el género femenino.
El currículum en el contexto costarricense: propuesta de definiciones para su conceptualización
Authors: Toruño Arguedas César
Published: May 2020

El presente ensayo realiza un análisis de la concepción del currículum en los enfoques curriculares técnico, práctico y crítico, como marco delimitador para la construcción de definiciones del currículum estructuradas a partir de la revisión teórica, una posición ecléctica de los enfoques práctico y crítico, la realidad del contexto costarricense y la premisa de utilizar definiciones para uso y práctica del currículum. Estas definiciones pretenden ser un insumo al análisis del currículum costarricense desde nuevas aristas de interpretación-acción y escenarios de transformación o reforma curricular.
Estrategias pedagógicas basadas en el enfoque por competencias: una experiencia en el curso de Diplomática
Authors: Marchena Priscilla Carranza , Recinos Melany Landaverde
Published: May 2020

Este artículo presenta los resultados de una investigación realizada en el curso de Diplomática, perteneciente al Bachillerato en Archivística, de la Universidad de Costa Rica (UCR), y su relación con el enfoque por competencias establecido en la reforma curricular vigente de este programa de estudio. Para llevar a cabo esta indagación, se aplicaron tres instrumentos: una entrevista a la docente del curso, un cuestionario dirigido al estudiantado del curso de Diplomática y una observación de clase cuyo objetivo principal fue obtener información basada en las estrategias pedagógicas utilizadas en el curso y su congruencia con el enfoque por competencias. Asimismo, se generó una producción didáctica (manual) basada en estrategias pedagógicas bajo el enfoque por competencias, la cual se socializó mediante un taller y se recolectaron datos en cuanto a la pertinencia de la propuesta pedagógica planteada. Los resultados obtenidos evidenciaron que, en el curso hay estrategias que podrían ser mejoradas e incorporadas. Se concluyó que el manual generado es un producto único en su índole, en el Bachillerato en Archivística de la Universidad de Costa Rica (UCR), el cual puede ser un recurso de utilidad y enriquecimiento para el proceso de mediación pedagógica.