bluuebunny/crossref_metadata_2025 huggingface dataset:
NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1
Authors: Wang Jiali , Chen Shuai , Xiang Wang , Zhu Qing , Ren Nianjun
Published: October 2023

Oxidored-nitro domain-containing protein 1 (NOR1) is a critical tumour suppressor gene, though its regulatory mechanism in oxidative stress of glioblastoma (GBM) remains unclear. Hence, further study is needed to unravel the function of NOR1 in the progression of oxidative stress in GBM. In this study, we evaluated the expression of NOR1 and nuclear respiratory factor 1 (NRF1) in GBM tissue and normal brain tissue (NBT) using quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot (WB), and investigated their relationship. We then induced oxidative stress in U251 cells through H2O2 treatment and conducted Cell Count­ing Kit-8, Transwell and wound healing assays to analyse cell proliferation, invasion and migration. Cell apoptosis was assessed by flow cytometry and TUNEL staining. We also measured the activities of superoxide dismutase and catalase, as well as the level of reactive oxygen species (ROS) using biochemical techniques. Via qRT-PCR and WB, the mRNA and protein expression levels of NOR1 and NRF1 were determined. Chromatin immunoprecipitation (ChIP) assays were applied to validate NRF1’s interaction with NOR1. Our results showed that the expression of NOR1 and NRF1 was low in GBM, and their expression levels were positively correlated. H2O2-induced oxidative stress reduced NRF1 and NOR1 expression levels and increased the ROS level. The ChIP assay confirmed the binding of NRF1 to NOR1. Over-expression of NRF1 attenuated the inhibitory effect of oxidative stress on the proliferation, migration and invasion of U251 cells, which was reversed by knockdown of NOR1.
Addition to the knowledge on the moth fauna (Insecta: Lepidoptera) of Bosnia and Herzegovina and Croatia
Authors: Koren Toni , Kulijer Dejan
Published: October 2023

Additions to the moth fauna of Bosnia and Herzegovina and Croatia are given. We report on first observations of five species and on reconfirmation of one species after eight decades. In Croatia, we recorded the species Eublemma cochylioides (Guenée, 1852) for the first time, while Eublemma himmighoffeni (Millière, 1867) has been confirmed in the country after 85 years. We report on the first observation of five moth species for Bosnia and Herzegovina: Triodia adriaticus (Osthelder, 1931), Eumera regina Staudinger, 1892, Dryobotodes monochroma (Esper, 1790), Lithophane lapidea (Hübner, [1808]) and Nycteola columbana (Turner, 1925). Even though these records could be expected due to species general distributions, they fill the knowledge of moth diversity of both countries and the wider region.
O lugar do silêncio nas literaturas africanas. O não-dizível como o esquecimento pós-traumático nos textos de Angola e da Guinée Equatorial
Authors: Díaz-Szmidt Renata
Published: October 2023

The article analyses the space of literary silence as a specific, metaphorical and intelectual space, an idea derived from Pierre Nora’s concept of “space of memory” (1984). In the context of sociocriticism and geopoetics reflexions, we analyse the silence in the literature of Angola and Equatorial Guinea searching the difference between the unspoken due to political and ideological reasons, prohibitions or taboos and the unspoken related to the impossibility to speak about the traumatic experiences suffered by African colective and cultural subject (Edmond Cros). We focus on the unspoken as post-traumatic amnesia in the works of José Eduardo Agualusa and Pepetela from Angola and in the novels and tales of Leoncio Evita Enoy and Donato Ndongo Bidyogo from Equatorial Guinea. The conclusion is that the space of silence in these texts is the result of a post-traumatic disorder caused by trans-Atlantic slave trade.
A Time Splitting Method for the Three-Dimensional Linear Pauli Equation
Authors: Gutleb Timon S. , Mauser Norbert J. , Ruggeri Michele , Stimming Hans Peter
Published: October 2023

We analyze a numerical method to solve the time-dependent linear Pauli equation in three space dimensions. The Pauli equation is a semi-relativistic generalization of the Schrödinger equation for 2-spinors which accounts both for magnetic fields and for spin, with the latter missing in preceding numerical work on the linear magnetic Schrödinger equation. We use a four term operator splitting in time, prove stability and convergence of the method and derive error estimates as well as meshing strategies for the case of given time-independent electromagnetic potentials, thus providing a generalization of previous results for the magnetic Schrödinger equation.
The PRIDx framework to engage payers in reducing diagnostic errors in healthcare
Authors: Ali Kisha J. , Goeschel Christine A. , DeLia Derek M. , Blackall Leah M. , Singh Hardeep
Published: October 2023

Objectives

No framework currently exists to guide how payers and providers can collaboratively develop and implement incentives to improve diagnostic safety. We conducted a literature review and interviews with subject matter experts to develop a multi-component ‘Payer Relationships for Improving Diagnoses (PRIDx)’ framework, that could be used to engage payers in diagnostic safety efforts.

Content

The PRIDx framework, 1) conceptualizes diagnostic safety links to care provision, 2) illustrates ways to promote payer and provider engagement in the design and adoption of accountability mechanisms, and 3) explicates the use of data analytics. Certain approaches suggested by PRIDx were refined by subject matter expert interviewee perspectives.

The PRIDx framework can catalyze public and private payers to take specific actions to improve diagnostic safety.

Outlook

Implementation of the PRIDx framework requires new types of partnerships, including external support from public and private payer organizations, and requires creation of strong provider incentives without undermining providers’ sense of professionalism and autonomy. PRIDx could help facilitate collaborative payer-provider approaches to improve diagnostic safety and generate research concepts, policy ideas, and potential innovations for engaging payers in diagnostic safety improvement activities.
Introduction: stylistic approaches to narrative empathy
Authors: Fernandez-Quintanilla Carolina , Stradling Fransina
Published: October 2023

This article introduces the special issue by outlining the current state of research into the role of textual-linguistic features in eliciting narrative empathy. Firstly, we address the complexities around defining the term ‘narrative empathy’ and provide some definitional criteria. We then review the ways in which the role of language in narrative empathy has been studied to date in narratology, literary studies, empirical study of literature and stylistics. Based on this review, we argue that stylistic approaches allow for the much-needed exploration of specific linguistic techniques that may contribute to narrative empathy, while also taking into account other contextual factors to address the local nature of reading effects. Finally, we summarise how the contributions to this special issue showcase the affordances of stylistic analysis for the study of narrative empathy and offer new insights into the ways narrative empathy is elicited during the reading process.
From witness to accomplice: the manipulation of readers’ empathy through consciousness representation in Patricia Highsmith’s The Talented Mr Ripley
Authors: Bourget Juliette
Published: October 2023

Within the field of narrative empathy studies, the concept of “negative empathy,” meaning a sharing of emotions with morally negative characters, has become increasingly discussed. Through the examination of The Talented Mr Ripley (1955) by Patricia Highsmith, this article contributes new insights into narratological and stylistic devices eliciting readers’ empathy. This study analyses responses from expert and non-expert readers to understand how they conceptualise empathy and qualify their engagement with the novel’s eponymous character. I argue that the novel’s figural narration, which involves extensive displays of the character’s mind and silencing the narrator’s moral guidance, invites empathy. Finally, I suggest that Highsmith manipulates her readers through three related stylistic techniques (free indirect discourse, stylistic contagion and equivocal sentences), which blur the lines between the third-person narration and the character’s inner discourse. By insidiously presenting the hero’s behaviour as sensible and justified, Highsmith persuades readers to become not only witnesses but accomplices to Ripley’s crimes.
I fucking love you! Emotional address in Fleabag, or how viewers’ empathy becomes voyeurism
Authors: Neveux Julie
Published: October 2023

This paper examines the effects of emotional language and telecinematic direct address in the BBC television series Fleabag (2016–2019) on viewers’ empathetic engagement, showing how multimodal narratives can invite empathy. In this series, direct address, often used to create intimacy with the audience, is the vehicle through which the eponymous protagonist shares or does not share her emotional states with those within or outside the diegesis. This way of communicating her feelings, I argue, shapes and intensifies viewers’ potential empathetic engagement in different ways throughout the series. In particular, I explain that the way in which Fleabag recurrently uses expressive language, most prominently swear words, while addressing the audience, initially invites viewer’s empathy in Season 1, before a stylistic shift in Season 2 eventually redefines this kind of emotional address: at the end of the series, viewers’ empathy is disinvited, positioning them as unwanted voyeurs.
Evaluation of the risk factors for noncommunicable diseases in patients with inborn errors of amino acid metabolism receiving nutrition therapy
Authors: Balci Mehmet Cihan , Karaca Meryem , Yesil Alihan , Selamioglu Arzu , Korbeyli Huseyin Kutay , Durmus Asli , Ak Belkis , Kozanoglu Tugba , Hacioglu Ilknur , Gokcay Gulden Fatma
Published: October 2023

Objectives

There is growing concern about the low-protein and high-energy diet therapies used in the treatment of inherited amino acid metabolism disorders. We aimed to identify the risk factors for noncommunicable diseases that may arise from nutritional therapies and suggests approaches that may prevent the development of the noncommunicable diseases.

Methods

The present study evaluates 112 patients, on long-term nutritional therapy for at least the last 2 years with a diagnosis of an inborn error of the amino acid metabolism, and their 28 healthy siblings. The participants are assessed for the development of overweight and metabolic syndrome based on an analysis of anthropometric parameters, body composition and the results of biochemical tests.

Results

Anthropometric measurements including BMI, weight Z-score, waist circumference and fat mass were not significantly different between patients and controls. Height Z-scores were similar in phenylketonuria patients compared to controls, but lower in urea cycle disorders, organic acidemia and maple syrup urine disease groups. No increased risk of development of overweight or metabolic syndrome was detected in the patient group, while there were findings suggesting malnutrition in patients diagnosed with urea cycle disorders. There was a correlation between patients’ BMI and C3-carnitine levels in organic acidemia patients and leucine levels in maple syrup urine disease patients.

Conclusions

All forms of malnutrition can be prevented in patient groups receiving limited nutrients under a dietary management protocol, based on the findings of anthropometric and biochemical evaluations and analyses of body composition.
IUPAC/CITAC Guide: Evaluation of risks of false decisions in conformity assessment of a substance or material with a mass balance constraint (IUPAC Technical Report)
Authors: Pennecchi Francesca R. , Kuselman Ilya , Hibbert D. Brynn
Published: October 2023

A Bayesian multivariate approach to the evaluation of risks of false decisions on conformity of chemical composition of a substance or material due to measurement uncertainty is adapted to cases for which the composition is subject to a mass balance constraint. The constraint means that sum of the actual (“true”) values of the composition component contents under conformity assessment is equal to 1 (or 100 %) or another positive value less than 1 (less than 100 %). As a consequence, the actual values of the component contents are intrinsically correlated. Corresponding measured values of the component contents are correlated also. Any correlation can influence evaluation of risks of false decisions in conformity assessment of the substance or material chemical composition. A technique for appropriate evaluation of the relevant risks, including evaluation of the conformance probability of a subject or material composition, is discussed for different scenarios of the data modeling, taking into account all observed correlations. A Monte Carlo method is applied in the R programming language for the necessary calculations. Examples of evaluation of the risks are provided for conformity assessment of chemical composition of a platinum-rhodium alloy, pure potassium trioxidoiodate, a sausage, and synthetic air.
Ischemic cerebrovascular disease caused by genetic mutation and patent foramen ovale
Authors: Eruyar Esra , Honca Tevfik , Bakır Fatih
Published: October 2023

Objectives

The search for genetic mutations is very important in younger patients and other age groups with a history of recurrent cerebrovascular diseases (CVD) and a family history of other causes to be excluded. The aim of this study is to define the characteristics of genetic mutations in the etiology of ischemic stroke.

Methods

Twenty-three patients with acute CVD in the last 1 year and only genetic mutations acknowledged in the etiology were retrospectively analyzed. We determined the frequency of the genetic mutations that are observed in cerebral arterial events (CAE) and cerebral venous thrombosis (CVT).

Results

All patients had at least one genetic mutation and 19 of them had arterial events and 4 had venous thrombosis. MTHFR mutation was the most common mutation and PAI-1 mutation was the second in line for the arterial events. PAI 4G/5G, MTHFR A1298 and FV mutations were most frequently observed in venous events. Patent foramen ovale (PFO) was detected in 14 patients (%74) with CAE.

Conclusions

We concluded that multiple gene mutations may significantly increase the development of CVD. CVD is most commonly associated with MTHFR, PAI-1 or FV gene mutations and is most commonly seen in CAE. MTHFR mutations showed moderate linear correlation in the development of arterial events and FXII and FXIII mutations in venous events. The association of thrombophilia and PFO is high in patients who have undergone CAE, especially responsible for recurrent events. This study will need to be confirmed by prospective studies with larger sample and control group.
Hullámvasúton. Tóth József és a magyar társadalomföldrajz
Authors:   Institute of Geography and Earth Sciences, University of Pécs, Dövényi Zoltán
Published: October 2023

The study attempts to place József Tóth in Hungarian human geography, and primarily seeks the answer to whether he had such an outstanding role that we can even talk about “The era of József Tóth”. In order to answer this question, the professor’s career is outlined in three approaches, as they basically determine whether someone can be called an epoch-making scientist. These are, in order, outstanding academic performance, managerial ambitions and aspirations and professional institutional background. József Tóth was undoubtedly an outstanding figure in Hungarian human geography, but he could not really give it the style he envisioned. The main reasons for this were lack of academic membership and of a leading position in a research institute.
FEMENINO DE CARGOS, PROFESIONES Y ACTIVIDADES LABORALES SEGÚN PERCEPCIÓN DE LA POBLACIÓN Y LA REAL ACADEMIA ESPAÑOLA
Authors: Alcaide-Aranda Lourdes Ivonne del Carmen , Molina-Quiñones. Helfer Joel , Aguilar Alcaide Carlos Enrique , Otero Romero María del Carmen , Goicochea-Parks Doris Isabel , Herrera Estrada Pahola Janira
Published: October 2023

Existe un avance lento en las nominaciones de cargos, profesiones y actividades laborales, desde un enfoque de género, por parte de la Real Academia Española (RAE), que además no está acorde con el lenguaje hablado por la mayoría de la población y es inverso al uso y aplicación de algunas expresiones. Es por ello que el propósito de esta investigación fue desarrollar un estudio sistemático del uso de los vocablos con marcador de femenino relacionados con el ejercicio de un cargo, profesión o actividad laboral, propuestos en el Diccionario de la Lengua Española (DLE) en su vigesimotercera edición del año 2014 para contrastar la posición normativa de la RAE con su uso real y cotidiano. Con enfoque cuantitativo, diseño no experimental de corte transversal, descriptivo comparativo y muestra no probabilística de 465 estudiantes y docentes de instituciones de educación superior de cuatro regiones políticas del Perú. Los resultados evidenciaron que, de los 24 cargos, estudiados con denominaciones recomendadas por la RAE, el 42% (10) no fueron aceptados por los docentes y estudiantes; asimismo, se evidencia que aún siguen predominando los sesgos sexistas en el empleo de las palabras que se aplican a hombres y mujeres. Se concluyó en que la RAE está incorporando las denominaciones de cargos, profesiones y actividades de manera lenta y que las denominaciones propuestas por la RAE no están acordes con el uso de la población.
Evaluation model for modular children's wooden storage cabinet design
Authors: Zhao Yin , Xu Yunjia
Published: October 2023

The design evaluation method of furniture products was explored for modular children’s wooden storage cabinets. An evaluation model consisting of the Kano model, hierarchical analysis, and grey relational analysis is proposed. A 25-member panel of experts was involved in the development of the evaluation guidelines and the scoring of the program. The expert group used the KJ method to obtain evaluation guidelines for modular children’s wooden furniture that met the requirements of the hierarchical analysis method and screened the functional indicators through 103 validated questionnaires for the Kano model. The evaluation guidelines of modularized children’s wooden storage cabinets were thus obtained, which are both comprehensive and targeted. Then, hierarchical analysis and grey relational analysis were combined to select the solution with the highest grey weighted correlation result as the best solution. The feasibility of the grey comprehensive evaluation method, which combines subjective preference and objective empowerment, in the field of furniture was confirmed through the practice of selecting the best of the three modular children’s wooden storage cabinet design solutions, and the evaluation preference of the modular children’s wooden storage cabinet was uncovered. The design model provides an innovative evaluation tool for children’s furniture manufacturers to optimize their sales strategies.
Does Tax Effort Moderate the Effect of Government Expenditure on Regional Economic Growth? A Dynamic Panel Data Evidence from Indonesia
Authors: Amri Khairul , Masbar Raja , Nazamuddin B. S. , Aimon Hasdi
Published: October 2023

Our research study aims to analyze the effect of government expenditure on goods and services and capital toward regional economic growth in Indonesia. We position local tax effort as a moderating variable between economic growth and government expenditures. Using a panel data set of 24 provinces in Indonesia from 2006 to 2015, a dynamic model of GMM was applied to estimate the effect of public expenditure on growth. The research study provides empirical evidence that the two kinds of public spending positively and significantly affect economic growth. Conversely, local tax efforts negatively affect economic growth. Besides, local tax efforts also reduce the positive impact of capital expenditure on economic growth. In other words, local tax efforts negatively moderate the influence of government expenditure on the output growth of the regional economy.
General conception of the studies of mathematics and their successful realization at Vilnius Pedagogical University
Authors: Banys Jonas , Griniuvienė Liucija , Naudžiūnienė Vanda
Published: October 2023

In this paper enrolment and study problems in the faculty of Mathematics and informatics of Vilnius Pedagogical university are discussed.
Biological peculiarities of artificial reproduction of sturgeons (Acipenseriformes) (a rеview)
Authors:   National University of Life and Environmental Sciences of Ukraine, Kyiv, Kuzmenko O. , Vovk N. ,   National University of Life and Environmental Sciences of Ukraine, Kyiv
Published: October 2023

Purpose. To analyze the scientific data of domestic and foreign authors regarding the peculiarities of artificial reproduction of sturgeonss (Acipenseriformes). To investigate the state of study of the phenomenon of polyspermic fertilization in sturgeons and the factors that induce it in the conditions of artificial reproduction and cultivation. Findings. A review analysis of the results of scientific studies by domestic and foreign authors was carried out on the pecularities of artificial reproduction of sturgeons and the phenomenon of polysperm fertilization of their eggs in controlled conditions of aquaculture. It is shown that information on the problems of sturgeon polyspermy and its induction by various factors was practically absent in the available professional literature in recent years. Since during the artificial reproduction of sturgeons, a significant number of embryos have atypical development, which leads to their death even before hatching, it has been suggested that atypical forms of cell division were caused by polyspermy. The conducted studies added to the knowledge about the peculiarities of the structure of the sturgeon egg envelope and the processes that occur during fertilization. Despite the fact that there is a natural mechanism to prevent the possibility of polyspermic fertilization, this phenomenon occurs quite often, causing an impairment of zygote fragmentation at the initial stages of embryogenesis, and therefore a decrease in the yield of larvae. Understaning of the mechanism of blocking polyspermy in sturgeons and the factors that induce it requires further studies. The list of scientific articles includes 61 sources, 58 in English. The published publications mainly cover the period of the last twenty years. Practical value. A review of data from scientific and professional sources on the specified topic will allow a comprehensive approach to the understanding of the peculiarities of artificial reproduction of sturgeons, the phenomenon of polyspermy and increasing the yield of larvae in sturgeon farming. Review material on this topic can be interesting and useful for scientists, practitioners, students whose interests are related to aquaculture and used in the educational process of training specialists in specialty 207 “Aquatic bioresources and aquaculture”. Keywords: aquaculture, sturgeons (Acipen­seriformes), eggs, egg envelope, micropyle, fertilization, cortical reaction, polyspermy, embryos.
Black carp (Mylopharyngodon piceus Richardson, 1846). Thematic bibliography
Authors:   Institute of Fisheries NAAS, Kyiv, Hrytsynyak Ir. , Shvets T. ,   Institute of Fisheries NAAS, Kyiv
Published: October 2023

Purpose. Forming a thematic bibliographic list of English-language publications on molecular-genetic, immunological, physiological-biochemical, as well as ecological and individual biological features of black carp (Mylopharyngodon piceus L.). Methods. The complete and selective methods were applied in the process of the systematic search. The bibliographic core have been consisted of English-language scientific publications from resources available to users of the Institute of Fisheries NAAS Scientific Library. Results. There was composed the thematic list of publications with a total quantity of 89 sources covering the time interval from 1995 to 2023, and highlighting the biological and ecological characteristics of a representative of the Cyprinids, the black carp, as well as considering the issue of its physiological, biochemical, genetic, and immunological features. The literary sources are arranged in alphabetical order by author or title, and described according to DSTU 8302:2015 “Information and documentation. Bibliographic reference. General principles and rules of composition”, with the amendments (code UKND 01.140.40), as well as in accordance with the requirements of APA style — international standard of references. Practical value. The list may be useful for scientists, practitioners, students, whose area of interests includes issues of biological research of Cyprinids, in particular black carp (Mylopharyngodon piceus L.). Key words: black carp, immunology, genetic indicators, biochemical indicators.
A Multisystem Approach to Improving Autism Care
Authors: Habayeb Serene , Inge Anne , Myrick Yetta , Hastings Amanda , Long Melissa , Hoffman Sarah Barclay , Parker Shaakira , Theodorou Penelope , Soutullo Olivia , Beers Lee , Godoy Leandra
Published: October 2023

Children with autism face significant barriers to accessing evaluations and intervention services often because of confusing referral processes, lack of centralized coordination across organizations serving children with autism, insurance coverage gaps, multiyear waitlists for diagnostic services, and limited provider knowledge about autism. Racism and systemic inequities exist and persist in autism care across the United States. This article reviews targeted initiatives implemented by a multidisciplinary team to advocate for, and address barriers faced, by autistic children and their families in Washington, DC. We describe initiatives across multiple levels of the health care system including: 1. infrastructure-building initiatives (eg, coalition-building, policy, and advocacy); 2. enabling services (eg, population- and community-level supports that increase provider capacity to serve children’s and families’ needs); and 3. direct services (eg, innovative, gap-filling programs that directly serve children and families). We review outcomes and describe lessons learned.
CHARACTERISTICS OF THE SELF-IMAGE OF ADULTS WITH DIFFERENT LEVELS OF QUALITY OF LIFE
Authors: DONETS O. , LISOVA P.
Published: October 2023

The article examines the problem of manifestations of the self-image of adults in conditions of social crisis. The position is formulated that the meaningful components of the self-image are related to the subjective well-being of the individual and his quality of life. The authors of the article focus attention on the adaptive potential of the self-image of the adult personality. Based on the material of the empirical research, a comparative analysis of the parameters of the self-image of respondents with high and low levels of the quality of life is carried out. In the course of the conducted research, differences between the respondents with high and low levels of the quality of life was proved in a number of meaningful components of the self-image, such as the strength of the self, self-criticism and the ability to control one's own behavior, ideas about one's social reputation, openness of the individual to interact with others and assimilation of new experience increase the potential of social adaptability of the individual. It is suggested that these indicators can increase the potential of social adaptability of an individual. The potential of self includes the reflection of personal meanings and the values system and increases the subjective perception of the quality of life. The results of the empirical study clearly show that the self-image and the quality of life are in direct and indirect relationship between each other.
A NATIONAL ANTHEM AS A CONSTRUCT OF THE MENTAL SPACE OF NATIONAL IDENTITY
Authors: ASTAPOVA-VYAZMINA Olena Igorivna
Published: October 2023

The purpose of the article is to determine the mental space of national identity by analyzing the semantic component of the national anthem. The national anthem can be considered as a social code that forms a citizen and as an ordinary text with its semantic structured levels. The national anthem is a political symbol and therefore forms two meanings: intent and influence. In the study, we combine the theory of mental spaces by G.Fauconnier and Ch.Fillmor’s frames semantics to visualize the conceptual model of Ukrainian national identity. Research results: Designating the national anthem as a patriotic work that describes and symbolizes the history and traditions of the country, we articulate the generation and manifestation of social values by the anthem. Based on this position, the article proposes a conceptual model of the mental space of the Ukrainian national identity, which was initiated by the anthem of Ukraine. The basis of the scheme is a figurative fusion of three macro-worlds: Glory-Ukraine-Freedom, which symbolizes the value component that holds around itself the basic concepts of national identity.The article compares the text of the national anthem «Shche ne vmerla Ukraina…» written by P.Chubinsky and the text edited by M.Verbitsky. The symbolic construction of the text of Chubinsky’s anthem, published in 1963, broadcasts a conceptual model of future actions. The names Zalizniak, Nalyvaiko, Triasylo embody the ideal of Cossack chivalry, past times, which are the basis for future generations to follow. The concept of “national identification borders” includes not only geographical names, the Black Sea, the Carpathians, the Dnipro (in the text «from the Syan to the Don»), but also indexical categories – «inviolability», «integrity of the state», «integrity of the territory», «unitaryness», and as well as symbols embodied in names, for example, Crimea, Odesa, Lviv, Kharkiv. In the context of the semantic analysis of the text of the national anthem, its influence on the mental state of the state is recognized, which is reflected in the global peace index and the global terrorism index. A nation can be presented with ethnic, territorial, cultural, and political components. But there must also be abstract ideas, a mental space that makes it visible.
J.BAUDRILLARD ABOUT THE PHENOMENON OF CHAOS: TO THE QUESTION OF THE SPECIFICS OF THE IMPLEMENTATION OF MODERN COMMUNITY SOCIAL WORK
Authors: OSETROVA Oksana
Published: October 2023

The modern realities of life in Ukraine, plunged into war by the Russian Federation, as well as those countries that are in a state of ontological threat, with new force actualize the problem unfolding in the social plane (we are talking about the antinomy of “chaos – stability”). In other words, modern social cataclysms – COVID-19 and war – have disrupted the stability of everyday life. The presence of the threat of nuclear escalation of the international conflict expands the metaphysical horizons of thanatological and suicidal problems, the aggravation of which can destroy the established order of the civilized world, which has found itself in a borderline situation. In view of the above, the purpose of this study is to clarify the essence of the phenomenon of chaos and social processes derived from it – the end, catastrophe, according to the philosophical views of the French thinker J.Baudrillard. Achieving the specified goal will contribute to the development of modern methods and technologies of social work in the community to minimize/overcome difficult life circumstances determined by the war situation. J.Baudrillard was deeply convinced that chaos is not completely opposed to rationality. The thinker believed that the dominance of rationality over reality is limited, because in reality it is not the subject who dominates the objective world, but the competition between the subject and the object. This study is focused on the actual existential problem of a person being in a borderline situation of chaos, determined by the reality of a thanatological situation, which enables the perspective of an ontological threat of a planetary scale, the origins of which are contained in the obsessive idea of total control, the realization of which leads to the disappearance of the social and the replacement of reality with an illusion, including even the illusion of security as a fundamental basis of the rescue economy, which is clearly observed in the ideology of the russian federation, which is based on the consumption of disaster in everyday life. The social work specialist’s awareness that chaos is not the end of everything (it is better to define this phenomenon as the end of the old order transformed into disorder, an example of which can be anomie), but the beginning of a new order, will directly contribute to the achievement of effective results in his professional activities in the community, in particular, in the direction of minimizing/overcoming the consequences of anomie as a type of chaos.
POLLSTER APPROACH VERSUS SOCIOLOGICAL APPROACH TO CONDUCTING ELECTORAL RESEARCH
Authors: KRYVOSHEIN Vitalii
Published: October 2023

The purpose of the study is to consider the advantages and disadvantages of pollster and sociological approaches to electoral research.The article shows that conducting electoral research in modern election campaigns is carried out equally by pollster (for purely political purposes) and sociological (for scientific and sociological purposes) technologies. It has been proven that optimal results can be achieved by combining pollster and sociological approaches to electoral research. It was determined that today the organization of an effective election campaign requires equally sociologists-pollsters and sociologists-analysts, the result of whose work is respectively collected empirical data and an analytical product, scientific expertise.It has been demonstrated that pollster and sociological approaches to conducting electoral research differ not only in the concepts of public opinion and the styles of its research, but also in the subject field. The electorate as a subject of electoral research acquires different content for different approaches. The pollster approach is more likely to understand the electorate as a circle of voters who vote for one or another party or candidate for an elected position and, in fact, are supporters of a certain political force or personality, while representatives of the sociological approach mostly consider the electorate as a collection of all citizens who vested with the right to vote and who exercise or do not exercise it under specially created conditions. It is argued that the integration of the subject fields of electoral polling and electoral sociological research will allow more effective and productive use of analytical potential in the election campaign, since such an organization of patronage work will help not only to record the results of electoral research, but also to predict the trends of electoral choice, the flow of votes, the reactions of electoral groups to specific political events. The availability of systematic ideas about the types of voters and their personal profiles will help to meaningfully approach the understanding of the electorate.
A green HPLC method for determination of mirtazapine in pharmaceutical products: Development, validation, and greenness assessment
Authors: Demir İbrahim , Bulduk İbrahim , Enginar Hüseyin , Çifci Cemal
Published: October 2023

Mirtazapine is an antidepressant medication used to treat the major depressive disorder in adults. In this study, two different chromatographic methods were developed for the determination of mirtazapine in pharmaceutical products. In the first method, An Extend C18 column (250 × 4.6 mm, 5 μm) was used and the temperature was kept constant at 25 °C. The mobile phase was determined as 0.1% formic acid solution and acetonitrile (80/20, v/v), and isocratic elution was applied. The flow rate of the mobile phase was determined as 1.0 mL min−1 and the injection volume was 20 µL. Detection was performed at 291 nm. using a UV detector. In the second method, ethanol was used as the organic modifier. The only difference between these methods was the organic modifier. All other conditions of the methods were the same. Both chromatographic methods were validated by ICH guidelines for various parameters such as selectivity, linearity, accuracy, precision, detection and quantification limit, and robustness. The determination coefficients of chromatographic methods were greater than 0.999 in the concentration range of 5–30 µg mL−1. of mirtazapine. Later, these chromatographic methods were applied to pharmaceutical formulations. Comparison of the obtained results in terms of means was made using Student's (t) test, and comparisons in terms of standard deviations were made using the Fischer (F) test. It was observed that there was no significant difference between these methods. These two methods were then evaluated using the AGREE-Analytical GREEnness metric software. The chromatographic method using ethanol as an organic modifier has been proposed as an excellent eco-friendly and analyst-friendly alternative for the determination of mirtazapine in pharmaceutical formulations.
Provisional Numbers and Rates of Suicide by Demographic Characteristics: United States, 2022
Authors: Curtin Sally C. , Garnett Matthew F. , Ahmad Farida B.
Published: October 2023

This report provides health data from the National Center for Health Statistics.
Exploring Mean Difference Tests and Implications for Special Education Research using Bayesian Theory and the ROPE Concept: with a Focus on Practical Significance Testing
Authors:   The Korean Society of Special Education, Yeo Seungsoo
Published: October 2023

The traditional t test has been the primary statistical method for testing the difference between two means in special education research. However, since the t-test is based on frequentist statistics, it has the limitation of being able to test the difference between statistically finite means, but not the practical significance that is meaningful in the field of education. In this study, we proposed an alternative to the traditional t test analysis method that utilizes Bayesian theory and the concept of ROPE (Region of Practical equivalence). In order to verify the differences between the two methods, this study analyzed example data from special education with both methods and compared the results. The results of this study show that Bayesian theory using ROPE is useful for testing practical significance in special education research, and can additionally provide richer analysis results for differences in means.
Critical Review of Tests for the Assessment of Stuttering
Authors: Varghese Aiswarya Liz , Balasubramanium Radish Kumar , Bajaj Gagan , Karuppali Sudhin , Bhaskaran Unnikrishnan
Published: October 2023

Stuttering, a condition affecting many individuals in society, is characterized by disruptions in the smooth flow of speech. It usually begins during childhood and involves involuntary repetitions, prolongations, blocks, avoidance, and accompanying behaviors while speaking. Identifying children at risk of stuttering enables intervention services during their early years when the chances for improvement are highest. A speech-language pathologist employs comprehensive procedures to evaluate a child's stuttering, including its accompanying behaviors and elements. This evaluation is typically extensive and includes interviews, analysis of case histories, and assessments of fluency, speech, language, and communication abilities. This article discusses the different formal tests which are incorporated in the assessment of stuttering.
Analysis of the leisure gap between young and elderly adults applying mixed research methods
Authors:   The Tourism Sciences Society Of Korea, Lee Hyerin , Kang Juhyun , Hong Seong-Hwa
Published: October 2023

In an egalitarian society, everyone should be provided with an environment where they can freely enjoy their leisure time and satisfy their leisure needs. However, in reality, the leisure environment for each individual is not equal, resulting in a leisure gap. While leisure utilization is a crucial issue for seniors who have relatively more leisure time, they are known to have lower leisure utilization abilities, leading to a significant leisure gap between seniors and other generations. The purpose of this study is to closely examine the current status of the leisure gap between seniors and youths and demonstrate the leisure disparities. To achieve this, a mixed research method was employed by utilizing the National Survey on Leisure Activities and senior focus group interviews. The analysis of the National Survey on Leisure Activities revealed leisure gaps in nine categories: leisure diversity, leisure cost, leisure time, public leisure resources perception, digital leisure activities, leisure perception, leisure satisfaction, leisure purpose, and leisure activity types. The results of a cross-generational comparative analysis on the factors influencing overall leisure life satisfaction, with the influences of education and income being controlled, revealed a total of 5 common determinants: perceived importance of leisure, sufficiency of leisure time, diversity of leisure activities, sufficiency of information about public leisure programs, and sufficiency of leisure costs. Furthermore, it was confirmed that leisure perception had the greatest impact on seniors' leisure satisfaction, and leisure cost had more influence than leisure time. Suggestions for resolving senior leisure disparities were provided, along with academic and practical implications.
Sichere und gesunde Arbeit in Zeiten des Klimawandels
Authors:   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund, Alexander Thomas , Bauer Stefan ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund, Bux Kersten ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund, Gabriel Katharina ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund, Klar Stefanie ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund, Romanus Erik ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund, Voß Stefan ,   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dortmund
Published: October 2023

Der Klimawandel mit seinen Folgen ist in der Arbeitswelt angekommen: Hitze und solare UV-Strahlung belasten die Beschäftigten jedes Jahr stärker. Beschäftigte im Freien sehen sich gesundheitlichen Gefährdungen durch nichtheimische Krankheitserreger und allergieauslösende Pflanzen ausgesetzt. Dekarbonisierung und Kreislaufwirtschaft bedeuten weitere Herausforderungen für den Arbeitsschutz. Deshalb ist es wichtig, auch in Zeiten des Klimawandels sichere und gesunde Arbeitsbedingungen zu garantieren.
Sitzmonitoring für Bewegung bei Büroarbeit
Authors:   Professur für Arbeitswissenschaft, Institut für Technische Logistik und Arbeitssysteme der Technischen Universität Dresden, Bührer Mark
Published: October 2023

Die Deutschen bewegen sich laut Weltgesundheitsorganisation (WHO) und der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA) zu wenig. Bewegungsmangel, insbesondere bei sitzender Büroarbeit, begünstigt physische und psychische Erkrankungen. Das Arbeitsschutzgesetz (ArbSchG) fordert in § 3 Führungskräfte zur Gefährdungsermittlung und zum Gesundheitsschutz ihrer Beschäftigten auf. Basierend auf einem Inertialsensor wurde ein Monitoring-Tool zur Bewegungsförderung von Beschäftigten bei Büroarbeit entwickelt und patentiert.
Aktuelles aus dem Arbeitsund Gesundheitsschutz (Folge 2): Klimawandel und die Risiken für die Arbeitswelt
Authors:   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA), Dresden, Bux Kersten
Published: October 2023

Die Folgen des Klimawandels haben immer größere Auswirkungen auf die Arbeitswelt. Aus Sicht des Arbeitsschutzes stellen sich verschiedene Fragen: Welche Auswirkung hat der Klimawandel konkret? Gibt es schon rechtliche Regelungen und Vorgaben für den Arbeitsschutz? Wer sind die verschiedenen Akteure in diesem Kontext? Nachfolgend wird darauf näher eingegangen.
Person-Job-Fit – Diagnostik und Interventionen mit dem Mini-ICF-APP-Fähigkeitskonzept bei Passungsproblemen am Arbeitsplatz
Authors:   Technische Universität Braunschweig, Psychotherapie und Diagnostik, Werk Lilly Paulin , Muschalla Beate ,   Technische Universität Braunschweig, Psychotherapie und Diagnostik
Published: October 2023

Person-job fit – Diagnostics and interventions with the Mini-ICF-APP capacity concept in the event of problems at the workplace Introduction: There is an increasing emphasis on occupational prevention measures to reduce periods of incapacity for work. The person-job fit can be used as a basis for tailored prevention. Capacity profiles of participants in work-related coaching with and without person-job misfit (in the sense of incapacity for work) were compared with each other. Methods: 199 employees from different industries took part in three one-hour coaching sessions. The coaching was conducted by a behavioural therapist in training under supervision. Forty coaching participants indicated that they had been unable to work for more than six weeks in the last 12 months. Nine participants were unable to work at the time of coaching. Thirteen psychological capacities (Mini-ICF-APP-S) were assessed in the baseline diagnostics and the impairments of participants with and without long-term incapacity for work were compared. Results: Participants with long-term incapacity for work had more often observable problems in endurance (35 % vs. 19 %, p = 0.002) and mobility (20 % vs. 5 %, p = 0.005). In the other capacities participants unable to work did not perceive any more severe capacity impairments than the others. The coaching particularly addressed the levels of primary and tertiary (overload) prevention and were thematically oriented according to the type of person-job misfit. Conclusions: Exploration of the capacities of employees when compared with the requirements of the workplace serves as an important basis for the demand-drive orientation of an individual measure. Keywords: person-environment fit – capacity for work – coaching – prevention
Writing our Futures Possible: Inspirations from the Dementia Letter Project
Authors: Driessen Annelieke , Cowan Hannah
Published: October 2023

Life with dementia urgently needs to be reimagined. The dominant social imaginary of dementia perpetuates a story in which people with dementia cannot have a life that is ‘good’. In this Position Piece we draw from eight letters written for the Dementia Letter project, in which the letters’ authors address their potential future self with dementia. We found that using the creative method of letter writing opened up possibilities for writers to fill uncertain futures with dementia with new experiences and relations, as well as opportunities for exploring multiple temporalities and versions of themselves. We highlight five inspirations from the letters: living with what is, the future as a space of possibility, populating the everyday, folding time, and cultivating multiple selves. Through these, we argue, alternative futures, and a present, with dementia can be reimagined, and made differently.