bluuebunny/crossref_metadata_2025 huggingface dataset:
Text Neck Syndrome in Children and Adolescents
Authors: David Daniela , Giannini Cosimo , Chiarelli Francesco , Mohn Angelika
Published: February 2021

Neck pain is a prevalent health problem, largely reported in adult patients. However, very recent data show that new technologies are inducing a shift in the prevalence of this relevant issue from adulthood to all of the pediatric ages. In fact, the precocious and inappropriate use of personal computers and especially cell phones might be related to the development of a complex cluster of clinical symptoms commonly defined as “text neck syndrome”. The purpose of this article is to analyze the new phenomenon of the “text neck syndrome”, the underlying causes and risk factors of musculoskeletal pain, that can be modified by changes in routine life, in different cultures and habits, and on the “text neck syndrome” as increased stresses on the cervical spine, that can lead to cervical degeneration along with other developmental, medical, psychological, and social complications. Findings support the contention that an appropriate approach for an early diagnosis and treatment is crucial to properly evaluate this emerging issue worldwide in children and adolescents who spend a lot of time watching smartphones and computers; additional research with more rigorous study designs and objective measures of musculoskeletal pain are needed to confirm significant relationships. Existing evidence is limited by non-objective measures and the subjective nature of musculoskeletal pain.
Discovering Spatial-Temporal Indication of Crime Association (STICA)
Authors: Jiang Chao , Liu Lin , Qin Xiaoxing , Zhou Suhong , Liu Kai
Published: February 2021

The importance of combining spatial and temporal aspects has been increasingly recognized over recent years, yet pertinent pattern analysis methods in place-based crime research still need further development to explicitly indicate spatial-temporal localities of pertinent factors’ influence ranges. This paper proposes an approach, Spatial-Temporal Indication of Crime Association (STICA), to facilitate identifying the main contributing factors of crime, which are operated at diverse spatial-temporal scales. The method’s rationale is to progressively discern the spatial zones with diverse temporal crime patterns. A specific implementation of the STICA approach, by combining kernel density estimation, k-median-centers clustering, and thematic mapping, is applied to understand the burglary in an urban peninsula, China. The empirical findings include: (1) both the main time-stable and time-varying factors of crime can be indicated with the disparities of temporal crime patterns for different spatial zones based on the STICA results. (2) The spatial range of these factors can enlighten the understanding of interactions for generating crime patterns, especially with regards to how temporally transient and spatially global factors can produce a locally crime-ridden zone through the mediation of stable factors. (3) The STICA results can reveal the spatially contextual effects of stable factors, which are of great value to improve modeling crime patterns. As demonstrated, the STICA approach is effective in exploring contributing factors of crime and has shown great potential for providing a new vision in place-based crime research.
A Novel Nutraceutical Formulation Can Improve Motor Activity and Decrease the Stress Level in a Murine Model of Middle-Age Animals
Authors: Tsoukalas Dimitris , Zlatian Ovidiu , Mitroi Mihaela , Renieri Elisavet , Tsatsakis Aristidis , Izotov Boris Nikolaevich , Burada Florin , Sosoi Simona , Burada Emilia , Buga Ana Maria , Rogoveanu Ion , Docea Anca Oana , Calina Daniela
Published: February 2021

Ageing is a genetically programmed physiological process that is modulated by numerous environmental factors, associated with decreasing physiological function, decreasing reproductive rate and increasing age-related mortality rate. Maintaining mobility performance and physical function in the elderly is the main objective of the successful ageing concept. In this study, we aimed to evaluate the beneficial effect of a novel nutraceutical formulation containing Centella asiatica L. extract, vitamin C, zinc and vitamin D3 (as cholecalciferol) on motor activity and anxiety with the use of a murine model of old animals, as a means of providing proof for clinical use in the elderly, for enhancing physical strength and improving life quality. Eighteen Sprague Dawley 18 months old male rats were divided into three groups and received corn oil (the control group) or 1 capsule/kg bw Reverse supplement (treatment group 1) or 2 capsules/kg bw Reverse supplement (treatment group 2), for a period of 3 months. The Reverse supplement (Natural Doctor S.A, Athens, Greece) contains 9 mg Centella asiatica L. extract, vitamin C (200 mg as magnesium ascorbate), zinc (5 mg as zinc citrate), vitamin D3 (50 µg as cholecalciferol) per capsule. Before and after the treatment, the motor function and behavioral changes for anxiety and depression were evaluated using the open-field test, elevated plus-maze test and rotarod test. The supplementation with Reverse (Natural Doctor S.A) supplement can improve the locomotor activity in old rats in a dose-dependent manner, as demonstrated by an increase in the latency to leave from the middle square, in the number of rearings in the open field test, in the time spent in the open arms and time spent in the center in the elevated plus-maze test and the latency to all in all three consecutive trials in the rotarod test. Stress also decreased significantly in a dose-dependent manner, following the treatment with Reverse supplement, as was demonstrated by the decrease in the number of groomings at the open field test and time spent in the dark and the number of groomings at the elevated plus-maze test.
Cervical Assessment for Predicting Preterm Birth—Cervical Length and Beyond
Authors: Reicher Lee , Fouks Yuval , Yogev Yariv
Published: February 2021

Preterm birth is considered one of the main etiologies of neonatal death, as well as short- and long-term disability worldwide. A number of pathophysiological processes take place in the final unifying factor of cervical modifications that leads to preterm birth. In women at high risk for preterm birth, cervical assessment is commonly used for prediction and further risk stratification. This review outlines the rationale for cervical length screening for preterm birth prediction in different clinical settings within existing and evolving new technologies to assess cervical remodeling.
Identification of the Response-Related Biomarker of Bimonthly Hepatic Arterial Infusion Chemotherapy
Authors: Moriya Kei , Namisaki Tadashi , Takaya Hiroaki , Kaji Kosuke , Kawaratani Hideto , Shimozato Naotaka , Sawada Yasuhiko , Douhara Akitoshi , Sato Shinya , Furukawa Masanori , Kitagawa Koh , Akahane Takemi , Yoshiji Hitoshi
Published: February 2021

Despite the availability of molecularly targeted agents for advanced hepatocellular carcinoma (aHCC), these are limited to compensated cirrhotic patients, and concerns about decreased hepatic functional reserve (HFR) and unknown adverse events, which may affect long-term survival, remain unaddressed. In this study, we enrolled 96 aHCC patients treated with bimonthly hepatic arterial infusion chemotherapy (B-HAIC) with cisplatin or sorafenib monotherapy (oral sorafenib 400 mg twice daily) not only to demonstrate its efficacy and significance but also to indicate preferable candidates by setting a response-related biomarker. Differences in treatment had no significant effect on overall survival (OS). The response rate in patients treated with B-HAIC was relatively higher than those treated with sorafenib. HFR was well maintained over the treatment course with B-HAIC, while it was significantly impaired with sorafenib. By employing multivariate analysis, we found negative trends between progression-free survival (PFS) periods and serum levels of alpha fetoprotein as well as des-gamma-carboxy prothrombin (DCP). In addition, a logistic regression analysis of the relationship between serum DCP levels and PFS periods over 420 days (14 months) showed that the PFS periods of patients with higher DCP was significantly shorter than those of patients with lower DCP (p = 0.02). Subsequently, the present study demonstrated the efficacy and safety of B-HAIC and identified a predictor of unpreferable patients. Based on these results, B-HAIC might be an alternative treatment after the implementation of new molecularly targeted therapies.
Metabolic Imaging in Non-Alcoholic Fatty Liver Disease: Applications of Magnetic Resonance Spectroscopy
Authors: Thiagarajan Prarthana , Bawden Stephen J. , Aithal Guruprasad P.
Published: February 2021

Non-alcoholic fatty liver disease (NAFLD) is poised to dominate the landscape of clinical hepatology in the 21st century. Its complex, interdependent aetiologies, non-linear disease progression and uncertain natural history have presented great challenges to the development of effective therapies. Progress will require an integrated approach to uncover molecular mediators, key pathogenic milestones and response to intervention at the metabolic level. The advent of precision imaging has yielded unprecedented insights into these processes. Quantitative imaging biomarkers such as magnetic resonance imaging (MRI), spectroscopy (MRS) and elastography (MRE) present robust, powerful tools with which to probe NAFLD metabolism and fibrogenesis non-invasively, in real time. Specific advantages of MRS include the ability to quantify static metabolite concentrations as well as dynamic substrate flux in vivo. Thus, a vast range of key metabolic events in the natural history of NAFLD can be explored using MRS. Here, we provide an overview of MRS for the clinician, as well as key pathways exploitable by MRS in vivo. Development, optimisation and validation of multinuclear MRS, in combination with other quantitative imaging techniques, may ultimately provide a robust, non-invasive alternative to liver biopsy for observational and longitudinal studies. Through enabling deeper insight into inflammatory and fibrogenic cascades, MRS may facilitate identification of novel therapeutic targets and clinically meaningful endpoints in NAFLD. Its widespread use in future could conceivably accelerate study design, data acquisition and availability of disease-modifying therapies at a population level.
Galactosemia: Towards Pharmacological Chaperones
Authors: Banford Samantha , McCorvie Thomas J. , Pey Angel L. , Timson David J.
Published: February 2021

Galactosemia is a rare inherited metabolic disease resulting from mutations in the four genes which encode enzymes involved in the metabolism of galactose. The current therapy, the removal of galactose from the diet, is inadequate. Consequently, many patients suffer lifelong physical and cognitive disability. The phenotype varies from almost asymptomatic to life-threatening disability. The fundamental biochemical cause of the disease is a decrease in enzymatic activity due to failure of the affected protein to fold and/or function correctly. Many novel therapies have been proposed for the treatment of galactosemia. Often, these are designed to treat the symptoms and not the fundamental cause. Pharmacological chaperones (PC) (small molecules which correct the folding of misfolded proteins) represent an exciting potential therapy for galactosemia. In theory, they would restore enzyme function, thus preventing downstream pathological consequences. In practice, no PCs have been identified for potential application in galactosemia. Here, we review the biochemical basis of the disease, identify opportunities for the application of PCs and describe how these might be discovered. We will conclude by considering some of the clinical issues which will affect the future use of PCs in the treatment of galactosemia.
Potential Role of miRNAs in the Acquisition of Chemoresistance in Neuroblastoma
Authors: Marengo Barbara , Pulliero Alessandra , Corrias Maria Valeria , Leardi Riccardo , Farinini Emanuele , Fronza Gilberto , Menichini Paola , Monti Paola , Monteleone Lorenzo , Valenti Giulia Elda , Speciale Andrea , Perri Patrizia , Madia Francesca , Izzotti Alberto , Domenicotti Cinzia
Published: February 2021

Neuroblastoma (NB) accounts for about 8–10% of pediatric cancers, and the main causes of death are the presence of metastases and the acquisition of chemoresistance. Metastatic NB is characterized by MYCN amplification that correlates with changes in the expression of miRNAs, which are small non-coding RNA sequences, playing a crucial role in NB development and chemoresistance. In the present study, miRNA expression was analyzed in two human MYCN-amplified NB cell lines, one sensitive (HTLA-230) and one resistant to Etoposide (ER-HTLA), by microarray and RT-qPCR techniques. These analyses showed that miRNA-15a, -16-1, -19b, -218, and -338 were down-regulated in ER-HTLA cells. In order to validate the presence of this down-regulation in vivo, the expression of these miRNAs was analyzed in primary tumors, metastases, and bone marrow of therapy responder and non-responder pediatric patients. Principal component analysis data showed that the expression of miRNA-19b, -218, and -338 influenced metastases, and that the expression levels of all miRNAs analyzed were higher in therapy responders in respect to non-responders. Collectively, these findings suggest that these miRNAs might be involved in the regulation of the drug response, and could be employed for therapeutic purposes.
ENSURING THE ACHIEVABILITY OF QUALITY GOALS BY PURPOSEFULLY CHANGING THE VALUES OF INDICATORS OF INDUSTRIAL ENTERPRISES SUBSYSTEMS UNDER THE LINEAR MANAGEMENT LAW
Authors: ANIKEEVA O.V. , IVAKHNENKO A.G.
Published: February 2021

In the paper a model of the enterprise quality management system with a linear law of management and the presence of two goals in the field of quality are presented. The results of modeling the areas of admissible values of the parameters of system properties of enterprise activity and coefficients reflecting the interaction of components of potential and organizational resistance on the example of JSC "Salyut" are presented. An approach is proposed to identify a set of admissible ranges of values of these parameters and coefficients that ensure the achievability of quality goals for industrial enterprises with a linear management law, consisting of five stages. The results of modeling purposeful management, according to the developed approach, are presented on the example of a light industry enterprise.
ANALYSIS OF THE STRESS-STRAIN STATE OF A RIVET JOINT USING THE ABAQUS CAE SYSTEM
Authors: LEONTYEV V.V.
Published: February 2021

The method for analyzing of stress-strain state characteristics of unloaded riveted joints performed with OST 1 11781-74 rivets has been developed using Coupled Euler-Lagrange finite element approach implemented in the CAD / CAE system Abaqus. A comparative analysis of the stress-strain state characteristics of the examined riveted joint’s finite element models using the Lagrangian and the Coupled Lagrangian-Eulerian finite element approaches has been conducted. A three- dimensional finite element model based on the CLE method has been proposed for further study of fatigue strength and durability of the loaded riveted joints.
PIPE BENDING WITH APPLICATION OF ACTIVE FRICTION FORCES
Authors: BORZENKOV M.I. , VDOVIN I.S. , RADCHENKO Yu.S. , TATARCHENKO N.V.
Published: February 2021

An engineering analysis of pipe bending along a circular copier with a deviation of flat material sections from the normal (by Love) position is performed, the dimensions of the active deformation area and the reactions of tools that generate friction forces are determined.
INFLUENCE OF FINE-DISPERSED ADDITIVE FROM CONCRETE SCRAP ON STRUCTURE FORMATION OF PORTLANDCEMENT
Authors: Ahmed A. , Lesovik R. , Al'-Bo-Ali W. , Lesovik G.
Published: February 2021

The object of the study is the effect of the introduction of a mineral additive (Ssp = 900 m2/kg) of the fraction (0.315–5 m) of the screening out of crushing concrete scrap into Portland cement for the production of various building products and structures. A fraction of concrete scrap of 0.315–5 mm is used in the work, since the X-ray phase analysis of various fractions of concrete scrap shows that these fractions have a rational content of non-hydrated particles of C3S and C2S. It is proved that the use of finely ground concrete scrap (Ssp = 900 m2/kg) as a mineral additive in Portland cement increaseINFLUENCE OF FINE-DISPERSED ADDITIVE FROM CONCRETE SCRAP

ON STRUCTURE FORMATION OF PORTLANDCEMENT

s the physical and mechanical properties of concrete. Comparative physical and mechanical indicators of the hardening of composite binders indicate that the most stable results with a uniform increase in strength is a composition with 5 % mineral additive, with an increase in strength from 2 to 7 days by 36 % and from 7 to 28 days by 46 %. It is found that the most rational are the compositions with 5 % and 10 % mineral additives providing an increase in the strength of the samples by 16% compared to the control composition. Due to the high dispersion, the mineral additive from concrete scrap acts as additional crystallization centers during the hydration of Portland cement, which leads to the creation of a skeleton coral-like structure, which additionally overgrows with submicroscopic crystals. With a specific surface area of 900 m2/kg, the best conditions are created for the formation of the primary frame and its further overgrowth with various crystalline calcium hydrates, which provide optimal density and strength.
SELECTION OF THE GROUND BASE MODEL IMPLEMENTED IN THE SCAD OFFICE
Authors: Luk'yanov A. , Tufanov V.
Published: February 2021

The article defines and compares the obtained sediments based on the results of applying the current regulatory methodology of the set of rules 22.13330.2016 "Foundations of buildings and structures" and numerical calculations using various models of the soil base implemented in the SCAD office software package, using the example of a frame-monolithic building of the residential complex which is called "Novaya zhizn" in Belgorod. A brief overview of methods for joint calculation of the foundation and aboveground parts using various models of the ground base: Pasternak with two bed coefficients, variable area bed coefficients in the sattilite CROSS program and the model of linear deformable half – space implemented in SP 22.13330.2016. Analytical calculation of the sediment value for set of rules 22.13330.2016 is performed "manually" by the method of layer-by-layer summation. The numerical calculation of the frame-monolithic building is performed as a single system "building-foundation – base". The values of sediments and bed coefficients C1 and C2 based on the results of numerical calculation are presented in the form of graphical isofields of displacements and bed coefficients. Based on the results of analytical and numerical calculations, the main conclusions are made and recommendations were presented on the applicability of each of the considered models of soil bases
THERMAL IMAGING STUDIES OF THE ORIGINAL HEAT EXCHANGER PLATE
Authors: Kuschev L. , Savvin N.
Published: February 2021

A modern method for studying the temperature field of heated bodies is considered. The object under study is a corrugated heat exchange plate with an original geometry. Heat exchangers are one of the main types of process equipment in heat supply systems. The article presents a comparison of two main types of heat exchange equipment: shell-and-tube and plate devices. The FLIR i50 thermal imaging device is characterized. A comparison is made between a standard heat exchange plate and a corrugated plate with spherical recesses located linearly on the areas between the corrugations. The use of original plates can increase the efficiency of the heat exchange process due to increased turbulization of the coolant. The relationship between the true temperature of a heated body and the brightness temperature of a black body is established. Experimental studies are carried out, in result the value of the average temperature of the heated body is obtained. This value is necessary for further calculation of heat transfer coefficients, which, in turn, are decisive in calculating the main parameter that characterizes the efficiency of heat exchange equipment-the heat transfer coefficient. The use of thermal imaging is the original way to study heat transfer processes, allowing to show the real increase of heat transfer coefficient of a plate heat exchanger.
PROTOTYPING OF THE INFORMATION SYSTEM OF AUTOMATIC MONITORING OF STUDENTS' MOTIVATION
Authors: Vinogradova D. A. , Krasavina M. S.
Published: February 2021

The article provides solutions on the basis of which the motivation and mood of employees can be monitored using IT and topicality of developing a similar information system for motivating students is substantiated.

Based on the tasks of the subject area, the requirements for the developed information system are formulated.

To determine the motivation associated with the psychological model, Vladimir Yudin’s model used in the pedagogic process was chosen as the base one. The system should calculate the indicators of the student's qualities and, on the basis of the transition rules, determine the likelihood of belonging to the psychological type, and also give recommendations on the formation of motivation. Monitoring student motivation will help

determine the list of activities in the university that contribute to the development of competences for each type of student. The article presents the developed user interfaces of the system to demonstrate its capabilities.
Kemandirian Pondok Pesantren Melalui Pendirian Bisnis Lembaga Keuangan di Kabupaten Pamekasan
Authors: Kusuma Nailah Aka , Uyun Jamiatul , Malia Evi
Published: February 2021

Abstrak:

Kemandirian pondok pesatren akan terwujud apabila pondok pesantren bisa memenuhi kebutuhan dan biaya penyelenggaraan pendidikkannya sendiri tanpa bergantung pada pihak eksternal pondok pesantren. Penelitian ini bertujuan untuk mengetahui bagaimana kemandirian dari pondok pesantren yang memiliki usaha bisnis berupa lembaga keuangan dan kemandirian dari pondok pesantren yang tidak memiliki usaha bisnis. Metode penelitian yang digunakan dalam penelitian ini yaitu kualitatif deskriptif dengan melakukan wawancara dan observasi langsung kepada informan yang berkaitan dalam variabel penelitian ini. Objek penelitian ini adalah pada pondok pesantren yang ada di Pamekasan. Hasil dari penelitian ini yaitu adanya bisnis pondok pesantren dapat menciptakan pondok pesantren yang mandiri dan tidak tergantung terhadap pihak ketiga baik itu pemerintah maupun alumni santri serta iuran dari santri, namun dengan adanya lembaga keuangan mikro syariah mampu memberikan kontribusi kepada pondok pesantren setiap tahun dari sisa hasil usaha (SHU) yang didapatkan dari lembaga keuangan mikro syariah, keuntungan juga diperoleh dari usaha bisnis pesantren yang lainnya.

 

Keywords: Pondok Pesantren, Lembaga Keuanngan Syariah, Kemandirian.

 

Abstract:

The independence of the pondok rapidly will be realized if the boarding schools can meet the needs and costs of conducting their own education without depending on external parties of the pesantren. This study aims to determine how independent Islamic boarding schools have business businesses in the form of financial institutions and the independence of Islamic boarding schools that do not have business. The research method used in this research is descriptive qualitative by conducting interviews and direct observation to informants who are related to this research variable. The object of this research is the Islamic boarding school in Pamekasan. The result of this research is that the existence of an Islamic boarding school business can create an independent Islamic boarding school and does not depend on third parties, both the government and santri alumni as well as contributions from students, but with the existence of Islamic microfinance institutions it only contributes to the boarding school every year from the remaining results. Business (SHU) obtained from Islamic microfinance institutions, profits are also obtained from other Islamic boarding school businesses.

 

Keywords: Islamic boarding schools, Islamic financial institutions, independence.
Sikap Ormas-Ormas Islam Lokal Di Pamekasan Terhadap Radikalisme Agama
Authors: Ali Ibnu , Mujiburrahman Mujiburrahman
Published: February 2021

ABSTRAK

Term radikalisme agama merupakan pembahasan yang sensitif dan dinilai berpotensi mendiskreditkan kelompok tertentu. Di kalangan pemikir belum ada kesepatan terminologis tentang radikalisme agama. Penelitian ini bertujuan mencari tahu bagaimana sikap ormas-ormas Islam lokal di Pamekasan terhadap radikalisme agama. Peneliti memfokuskan objek penelitian pada ormas-ormas Islam lokal di Pamekasan yaitu NU, Muhammadiyah, SI, Persis, Hidayatullah, dan FPI. Dengan metode kualitatif, data diambil melalui wawancara secara terstruktur terhadap sample yang diambil dari ormas, baik secara acak atau secara kolektif. Hasilnya, sikap ormas tersebut dapat dipahami dalam tiga komponen, yaitu kognitif, afektif, dan konasi. Secara kognitif, ormas-ormas tersebut memberikan pandangan yang berbeda-beda tentang term radikalisme agama. Ada yang mendefinisikan dengan jelas, baik secara luas maupun sempit. Ada yang tidak memberikan definisinya. Secara afektif, mayoritas menganggap persoalan ini sebagai isu dan stigma sehingga mayoritas mereka tidak setuju dengan term radikalisme agama. Dan secara konasi semua ormas Islam mengambil peran dalam menghadapi persoalan tersebut meski dengan intensitas yang berbeda.

 

Kata Kunci: Sikap ormas, radikalisme

ABSRACT

The term religious radicalism is a sensitive discussion and is considered to have the potential to discredit certain groups. There is no terminological agreement among thinkers about religious radicalism. This study aims to find out how the attitudes of local Islamic organizations in Pamekasan towards religious radicalism. Researchers focused on the object of research on local Islamic organizations in Pamekasan, namely NU, Muhammadiyah, SI (Syarikat Islam), Persis, Hidayatullah, and FPI. With a qualitative method, data were collected through structured interviews with samples taken from mass organizations, either randomly or collectively. The planned output is an accredited national journal, while the additional quotation is just books.As a result, the attitudes of these organizations can be understood in terms of three components, namely cognitive, affective, and conative. Cognitively, these mass organizations provide different views on the term religious radicalism. There are those who define it clearly, both broadly and narrowly. Some didn't give the definition. Affectively, the majority considered this issue as an issue and a stigma so that the majority of them did not agree with religious radicalism. And conventionally all Islamic mass organizations take a role in dealing with these problems even though with different intensities.

 

Keywords: the attitude of local Islamic organization, Radicalism
A new natural hybrid of Verbascum L. (Scrophulariacae) from Turkey
Authors: DUMAN Hayri , UZUNHİSARCIKLI Erkan , ÖZBEK Funda
Published: February 2021

Verbascum × aytachii nothosp. nov. H. Duman & Uzunh. (sect. Bothrospermae) is described and illustrated as a new natural hybrid from the Orhaneli (Bursa Region) area in Western Anatolia, Turkey. This species is identified to have some intermediate morphological and palynological characteristics that place it between the parents which are V. ekicii and V. basivelatum. A comprehensive description, ecology, a distribution map and a detailed illustration are provided. Furthermore, pollen morphological properties of V. × aytachii and its parents are compared via light (LM) and scanning electron microscopes (SEM).
Flow and Heat Transfer in a Trapezoidal Cross-Sectional Microchannel Heat Sink Using Nanofluid
Authors: EGE Faraz , TURGUT Oğuz , ELİBOL Emre Aşkın
Published: February 2021

In this study, the effects of microchannel number, volume concentration, Reynolds number, and nanofluid type on heat transfer and flow characteristics in the heat sink consisting of trapezoidal microchannels are investigated numerically. Governing equations are solved by assuming three-dimensional, incompressible, steady and laminar flow. The channel material is chosen as copper, and a constant heat flux boundary condition is defined on the upper wall of heat sink. For two different nanofluids, CuO-water and Al2O3-water, investigated parameters are the number of trapezoidal channels (n=3-5) in the heat sink, Reynolds number (Re=200-1500), and volume concentration (=0-4%). Results show that using nanoparticles in base fluid causes to increase both heat transfer coefficient and pressure drop. Heat transfer coefficient increases with increasing number of trapezoidal cross-sectional channel in the heat sink, nanofluid volume concentration and Reynolds number. Pressure drop enhances with enhancing Reynolds number and microchannel number in the heat sink. The nanofluid type and volume concentration do not importantly affect the friction factor. According to the performance index, it is seen that adding CuO nanoparticles in water is convenient, but Al2O3 nanoparticles in water is not appropriate. It is observed that volume concentration for CuO-water nanofluid affects the thermal performance, but volume concentration for Al2O3-water nanofluid does not affect.
Piaci kockázat és számszerűsítése az R szoftverrel
Authors: Pšenák Peter
Published: February 2021

Az elmúlt 30 évben a gazdasági válságok gyakorisága bizonyítottan nőtt. Tekintettel erre a tényre a pénzügyi szférában megnőtt a piaci kockázatelemzés fontossága. A gyakorlatban a VaR (Value at Risk) a leggyakrabban használt módszer a kockázat modellezésére. A publikációnk a piaci rizikó felmérési módszereit mutatja be, néhány gyakorlati példával azoknak előnyeivel és hátrányaival az R szoftver használata segítségével.
Thermoelectric transport properties of the van der Waals-type layered rhombohedral SnAs-based compound, EuSn2As2
Authors: Sakagami Ryosuke , Goto Yosuke , Karimata Harunari , Azuma Nobuhiko , Yamaguchi Michitaro , Iwasaki Suguru , Nakanishi Manami , Kitawaki Itsuki , Mizuguchi Yoshikazu , Matoba Masanori , Kamihara Yoichi
Published: February 2021

The thermoelectric transport properties of the van der Waals-type layered rhombohedral SnAs-based compound, EuSn2As2, have been investigated. A densified polycrystalline sample of EuSn2As2 with porosity (ϕ) of 2.4(9) vol.% exhibited a weak orientation to the c-axis for hexagonal coordination system; the weak orientation is parallel (P
∥) to the pressing direction of hot pressing. Measurements of electrical resistivity (ρ), Seebeck coefficient (S), and thermal conductivity (κ) were conducted perpendicular (P
⊥) to the pressing direction. The experimental values of ρ and S exhibit metallic temperature dependence and p-type carrier polarity. The power factor (P) was 0.51(8) mW m−1 K−2 at 673(4) K. Using the Wiedemann–Franz–Lorenz law, the phonon thermal conductivity (κ
ph) was estimated to be 0.4(6) W m−1 K−1 at 673(6) K. The dimensionless figure of merit, ZT, was 0.092(17) at 673(3) K.
Effect of high-energy heavy-ion irradiation on electromechanical coupling factor of piezoelectric lead zirconate titanate
Authors: Takechi Seiji , Fujita Shogo , Konishi Naoki , Miyachi Takashi , Kobayashi Masanori , Okudaira Osamu , Okada Nagaya , Fujii Masayuki , Shibata Hiromi , Murakami Takeshi , Uchihori Yukio
Published: February 2021

The variation of the electromechanical coupling factor of lead zirconate titanate (PZT) was studied using a piezoelectric PZT disk exposed to a 400 MeV/n xenon beam. The resonant and antiresonant frequencies were measured in pairs by an impedance analyzer in situ manner. A systematic behavior of the pairs resulted in a decrease of the coupling factor. It was found that the coupling factor linearly decreased with increasing integrated beam energy incident on the PZT disk while its surface temperature was equilibrium at room temperature. We discuss a possible PZT-based radiation detector for practical use in a high-radiation field.
Avaliação do conhecimento de professores e estudantes de graduação no manejo da avulsão
Authors: Paula de Andrade Carina , Verdinelli de Paula Reis Manuella
Published: February 2021

Objetivo: Avaliar o conhecimento e nível de experiência quanto ao manejo de dentes avulsionados dos docentes e acadêmicos de Odontologia da Universidade de Rio Verde-Goiás. Material e método: Um questionário impresso foi aplicado presencialmente pelos autores para 20 professores e 180 alunos, composto por informações sociodemográficas e questões específicas relacionadas à avulsão. Os dados foram tabulados e submetidos à análise estatística pelo teste Qui-quadrado. Resultados: Mais de 60% dos professores e alunos receberam treinamento em primeiros socorros para tratamento de traumatismos dentários, e sabem como proceder nesses casos. Quanto ao meio de armazenamento para dentes avulsionados, 35% dos professores e 44,44% dos estudantes responderam leite. Considerando que houve diferença significativa no grupo dos acadêmicos (p=0.007). Apenas 26,31% dos docentes e 21,11% dos acadêmicos conheciam sobre o tempo extra-alveolar para reimplante. Sobre o uso de contenção semirrígida em casos de avulsão, 75% dos professores e 61,66% dos estudantes responderam corretamente. O período de manutenção por 15 dias dessa contenção foi respondido por 57,89% dos professores e 48,33% dos estudantes. Neste ponto houve diferença estatisticamente no grupo dos alunos (p=0.006). Em relação ao tempo para realização do tratamento endodôntico, apenas 36,84% dos docentes e 31,66% dos estudantes, possuíam esse conhecimento. Considerando que houve diferença significativa no grupo dos acadêmicos (p=0.005). Sobre o tempo de acompanhamento radiográfico, 50% dos professores e 32,77% dos estudantes, responderam corretamente. Conclusão: O nível de conhecimento e experiência dos professores e estudantes foi insuficiente quanto à avulsão, necessitando-se de capacitação para o sucesso do prognóstico desses dentes.
Restauração estética de dentes conóides associada a recontorno gengival em paciente jovem: relato de caso
Authors: Fernandes Oliveira Bruno , Miguel Juliano Gonçalves , Magalhães Ana Paula Rodrigues
Published: February 2021

A busca por tratamentos dentários por razões estéticas tem aumentado muito devido ao grande impacto do sorriso na autoestima e bem-estar dos pacientes em seu convívio social. No planejamento estético reabilitador critérios dento-faciais, labiais, periodontais e pessoais devem ser levados em consideração na indicação de qualquer tratamento. O objetivo deste artigo é relatar um caso de sorriso gengival e dentes conóides em paciente jovem, tratada com uma abordagem minimamente invasiva. No exame físico foi possível observar o sorriso gengival causado pela erupção passiva alterada e microdontia isolada nos incisivos laterais superiores, o que prejudicava a harmonia do sorriso.  Foram propostos alguns planos de tratamento e diante do custo-benefício foram realizados aumento de coroa clínica estético sem retalho (“flapless”) dos incisivos centrais e laterais, e pré molares do lado direito superior, associada a clareamento dental caseiro supervisionado e restaurações diretas em resina composta sem preparo prévio da estrutura dentária. As restaurações foram guiadas por uma matriz de silicone obtida imediatamente e desgastada no tamanho final planejado com broca, sem a necessidade de enceramento diagnóstico. O resultado obtido com o tratamento proposto melhorou as proporções dento-faciais e gengivais, solucionando a queixa principal da paciente com preservação de estrutura dental sadia, restabelecendo estética e mantendo a função de forma adequada.
Building an Adversarial Attack Hat to Fool Facial Recognition
Authors: Frearson Morgan
Published: February 2021

The use of deep learning for human identification and object detection is becoming ever more prevalent in the surveillance industry. These systems have been trained to identify human body’s or faces with a high degree of accuracy. However, there have been successful attempts to fool these systems with different techniques called adversarial attacks. This paper presents an adversarial attack using infrared light on facial recognition systems. The relevance of this research is to exploit the physical downfalls of deep neural networks. This demonstration of weakness within these systems are in hopes that this research will be used in the future to improve the training models for object recognition. A research outline on infrared light and facial recognition are presented within this paper. A detailed analyzation of the current design phase and future steps of the of the project are presented including initial testing of the device. Any challenges are explored and evaluated such that the deliverables of the project remain consistent to its timeline. The project specifications may be subject to change overtime based on the outcomes of testing stages.
Geometric Derivative Filter for Image Enhancement
Authors: Hassanpour Hamid
Published: February 2021

This article introduces and explains geometric derivative filter as a new method for image processing and enhancing quality of images.. It's mathematical concept will be explored and some examples of applying this filter to images will we illustrated.
Revista Ciencia Multidisciplinaria CUNORI 2019
Authors: Villela Dra. Claudia
Published: February 2021

Para la actual administración del CUNORI es muy satisfactorio darle continuidad a este producto estratégico para la academia y la razón de ser de ésta: la creación y generación de conocimiento con su correspondiente divulgación, sociabilización, o puesta en común de lo que con no poco trabajo somos capaces de producir. Cada volumen editorial implica su propio esfuerzo y los lectores serán quienes juzguen los méritos y el nivel del logro alcanzado.
Preparation of layer-reinforced nanocomposite based on polytetrafl uoroethylene by laser ablation and ion-plasma modifi cation
Authors: Mashkov Yu.K. , Poleshchenko K.N. , Eremin E.N. , Teploukhov A.A. , Nesov S.N. , Semenyuk N.A. , Seropyan G.M. , Shubenkova E.G.
Published: February 2021

The results of researches devoted to solving the problem of obtaining of layered-reinforced nanocomposite
based on polytetrafluoroethylene are presented. To ensure the required adhesive strength between the polymer base
and the metal coating based on molybdenum, the surface layer of the base is reinforced with dispersed particles of
zirconium dioxide. It is found that when reinforced with zirconium dioxide, the structure of polytetrafluoroethylene
becomes more dense, and the ratio of atomic concentrations of fluorine and carbon in its composition decreases,
which indicates decrease in the number of saturated fluorocarbon bonds in the polymer and leads to higher chemical activity of polytetrafluoroethylene. The obtained data on change in the chemical state of the layered-reinforced
composite components indicate high degree of interaction between the polymer matrix elements, reinforcing components and coating elements in the area of the intermediate mesolayer.
Hard alloy coatings for turning of 09Kh17N7Yu steel
Authors: Mokritsky B.Ya. , Sitamov E.S. , Shelkovnikov V.Yu.
Published: February 2021

Specialized stainless 09Kh17N7Yu steel becomes more usable in various fields of mechanical engineering due to its
unique properties, but recommendations for parameters of the cutting mode and for rational tool materials are out of date.
Due to this, excessive consumption of tool materials is observed. It is necessary to develop new recommendations with
adaptation to high-performance processing on CNC machines. The recommendations of foreign tool manufacturers are
insolvent for choosing their tool, because there are no direct foreign analogues of this steel. Researches are carried out to
reduce the consumption of hard tool alloys of VK, ТК and ТТК groups, as well as number of foreign tool materials. The
possibility of using VК8 alloy with coatings for turning by removable standard hard alloy plates is established. Rational
coatings are chosen from the number of known coatings. New coatings are developed for specified operating conditions
Laser hardening of metallic materials
Authors: Kim V.A. , Aung Ngwe Thein  , Belova I.V.
Published: February 2021

The surface microstructure of metallic materials formed under the effect of laser radiation is characterized by high
degree of nonequilibrium, has layered structure consisting of the main three zones formed from the fused material,
the heat-affected zone and the tempering zone. As the laser radiation energy increases, the size of the modified layer
increases, and the coverage width of the melting zone and heat-affected zone is determined by the maximum penetration depth of the melting and polymorphic transformation isotherms. The distribution of microhardness over the depth
depending on the laser radiation energy is exponential or extreme, and the microhardness is usually maximum in the
heat-affected zone. As the laser energy increases, the microhardness of the hardened surfaces changes with extreme
dependence. Laser hardening of metallic materials is the result of two competing hardening and softening processes.
As result of mathematical processing of experimental results, empirical equations for the distribution of microhardness
over the depth of laser-hardened surface layers of various steels and ARMCO-iron are obtained. Empirical equations
consist of two terms, the first of which describes the processes of hardening, and the second — softening. The obtained
equations allow optimizing the laser hardening modes and predicting the hardened layer depth.
Innovative principles for manufacturing of solid ceramic end mills with antifriction wear resistant coatings for milling of diffi cult-to-machine nickel alloys
Authors: Grigor’ev S.N.
Published: February 2021

Innovative technological principles for manufacturing of solid ceramic end mills, including spark-plasma sintering of ceramic workpiece based on compositions α/β-SiAlON with additives of 10 and 20 % titanium nitride,
subsequent forming abrasive blasting and deposition of antifriction wear-resistant coatings of three compositions
TiN—Al/TiN, TiN—AlTiN/SiN and CrTiN—AlTiN—AlTiCrN/SiN are developed and tested. Rational modes
of sintering are established for powder compositions, and the composition of 80 % (90α + 10β) and 20 % TiN is
recommended as the most wear-resistant composition for ceramic milling tools. The role of coatings in increasing
of durability of ceramic tool during milling of INCONEL 718 nickel alloy is assessed. It is shown that TiN—
AlTiN/SiN coating provides 1.7 times higher resistance of ceramic milling cutters in comparison with uncoated tools
Olive Processing Industry, How to Avoid or Minimize the Environmental Impact of Heavy Metals (Case Study: Albania)
Authors: Bani Manjola
Published: February 2021

The development of olive production in Albania is considered as one of the priority branches of agriculture. After the 90s, the number of trees decreased significantly due to the abandonment of non-productive areas, but currently, there is a national plan to increase the planted area. According to forecasts to increase the amount of olives will increase the level of emissions. For this reason, the fate of application processing technologies with minimal impact on the environment should be emphasized. The analysis of these wastes is of interest because they are deposited on agricultural land, reducing productivity and thus affecting the country's economy. This study analyzes the environmental impact of the activity of olive oil processing lines, producing solid waste as secondary and liquid products. A processing plant in Lushnja, Albania was selected for this study. The factory uses 3-phase (3P) processing technology. Samples were taken during the intensive processing period in October-November 2020. Initially, samples were prepared for analysis, determined: number of solids, % of ash, carbon, acidity (pH), and conductivity. Heavy metals were determined at different wavelengths using UV-VIS spectrophotometers. The elements analyzed from the collected samples are K, Na, Mg, Cd, Pb, Zn, Fe, Cu. From the graph, the sample is characterized by increasing order: Pb <Cu <Mg <Fe <Zn <Cd <Na <K.
EU Data Protection Rules and the Lack of Compliance in Sweden
Authors: Herlin-Karnell Ester
Published: February 2021

In this short reflection paper, I will set out to explain how and why Sweden breaches EU data protection rules. I will start by providing a brief overview of the EU data protection framework to paint the background picture. Thereafter I will discuss the scope for derogating from the obligations set out in the GDPR and thereby test the Swedish exception and show that it is not proportionate and undermines the purpose of the GDPR. Subsequently, I will discuss why some core fundamental rights of EU law should not be possible to derogate from, when as in the Swedish case it seems to boil down to economic question of who gets to own the data. I will conclude by linking the question of the right to data protection and why licenses should not give companies a carte blanche to publish personal data about people in Sweden to the question of market access. There is an imbalanced relationship here, to use the internal market vocabulary, with Swedish people having all their private data published online while other EU states do not do that. Likewise, there is an external dimension here: the data is available on the internet globally and therefore third countries also access it.
Mycophenolate Mofetil for a Flare Child Lupus Nephritis: A Case Reports
Authors: Puspita Gina , Desy Rusmawatiningtyas  , Sumadiono
Published: February 2021

A B S T R A C TRenal involvement is the most common complication of systemic lupus erythematosus(SLE) and is also an important predictor of patient mortality. The incidence of flaresis estimated at 65% each year in patients with lupus nephritis. Therapy in lupusnephritis with flare also uses high doses of steroid agents and strongimmunosuppression agent. Mycophenolate mofetil (MMF) as a immunosuppressionagent tends to favor for flare in lupus nephritis. We describe a patient who had flarein lupus nephritis that resolved with high-dose steroid and MMF. The combination ofimmunosuppression agent and high-dose corticosteroid is an effective for control ofactive diseases. Cyclophosphamide as the steroid sparing agent was discontinuedbecause of adverse effect as well as hematuria. Partial remission was later achievedand maintained with MMF and corticosteroid after five month with protocol treatment.Thus, MMF while maintaining the steroid dose may induce remission for this case.
Acute Effect of Chili Consumption on Thermogenesis and Glycemic Response Following Oral Glucose Load in Men
Authors: Ávila-Seguel Muriel , Márquez-Urrizola Constanza , Granfeldt Gislaine , Saez-Carrillo Katia , Sharifi-Rad Javad , Pezzani Raffaele , Martorell Miquel
Published: February 2021

Hypoglycemic and thermogenic effects are attributed to the capsaicinoid compounds (capsaicin). The aim of this study was to evaluate the acute effect of the consumption of 5g of chili pepper on thermogenesis and the glycemic response. In a pretest-post-test quasi-experimental study, the energy expenditure (EE) of 15 healthy men was evaluated by using indirect calorimetry at rest and with the consumption of 5g of Capsicum annum. In addition, the glycemic response after an oral glucose load was evaluated. After the consumption of C. annum, there was a significant increase in the EE of all the participants during the first few seconds postchili consumption. In sedentary participants, the consumption of chili pepper caused a significant decrease of blood glucose levels. The consumption of chili pepper has a potential immediate thermogenic effect during the first few seconds and, in sedentary people, it has a potential hypoglycemic effect.