bluuebunny/crossref_metadata_2025 huggingface dataset:
VALIDASI METODE ANALISA PADA PENETAPAN KADAR KOENZIM Q10 DALAM SEDIAAN MIKROEMULSI MENGGUNAKAN METODE SPEKTROPHOTOMETER UV-VIS
Authors: Wulansari Silvi Ayu , Lubada Eziah Ika
Published: September 2020

Koenzim Q10 banyak digunakan dalam bidang kosmetika karena dapat digunakan sebagai antioksidan, namun koenzim Q10 memiliki kekurangan yaitu hanya dapat larut dalam minyak dan memiliki ukuran partikel yang besar sehingga sulit untuk masuk pada kulit. Koenzim Q10 diformulasikan dalam sediaan mikroemulsi untuk memperbaiki penetrasi dalam kulit. Untuk menunjang efek terapetik dari sediaan mikroemulsi perlu dikembangkan penetapan kadar Koenzim Q10 menggunakan spektrofotometer Uv-Vis, menggunakan pelarut [Acetonitril : 2-propanol (84:16)] dan diukur pada panjang gelombag 275 nm. Hasil penelitian menunjukkan bahwa koenzim Q10 linier pada rentang konsentrasi 25,5 – 153,0 ppmdengan LOD dan LOQ sebesar 5,25 µg/ml dan 17,48 µg/m. Metode peetapan kadar koenzim Q10 pada sampel mikroemulsi memiliki nilai akurasi dan presisi yang cukup baik dengan rata-rata perolehan kembali 100,70% dan SD 0,41% . Spektrofotometer UV-Vis dapat digunakan sebagai metode dalam penetapan kadar koenzim Q10 dalam sediaan mikroemulsi yang memenuhi persyaratan validasi penetapan kadar sediaan farmasi.
Role of Community Leaders as Motivator in Waste-Bank Management in Magetan Regency, Indonesia
Authors: Ragiliawati Retananda , Qomaruddin Mochammad Bagus
Published: September 2020

Background: Garbage is one of the unsolved problems in Indonesia. Riskesdas data for 2018 show that 63.2% of the quality of household waste management in Indonesia is in a bad category. The landfill site in Magetan Regency is currently overloaded. The waste bank is an alternative solution for solving problems. Tawanganom Village, Magetan District, Magetan Regency, won the Regency Level Healthy Village Competition in 2017 with fifth community association (RW 5) as the competition representative because it fulfilled the criteria of the championship, namely the existence of a waste bank. It is inseparable from the active role and social support of community leaders who motivate the community to participate in waste bank management. Objectives:  Describe the role of community leaders as motivators in supporting waste bank management, including emotional support, appreciation, instrumental, and information. Methods: The method used in this research is qualitative with a case study approach. In-depth interviews were conducted with informants consisting of housewives and community leaders involved in waste bank activities. The determination of informants was carried out purposively with in-depth interviews using an interview guide. Results: It shows that the role of community leaders as motivators significantly affects the sustainability of the waste bank in RW 5, Tawanganom Village, Magetan Regency. Community leaders show patience in guiding the community, providing appreciation and various rewards so that the community feels proud and appreciated, and enables the community to move independently in managing the waste bank. Conclusion: The role of community leaders as motivators impacts increasing community participation in waste bank management. The waste bank can run smoothly, supported by the attention and concern of the local government and community leaders who are aggressively providing information and suggestions related to waste bank management.
Sosialisasi Model Pembelajaran Double Critical Technology Society MGMP IPA SMP dan SMA Rayon III Kabupaten Kapuas Hulu
Authors: Darmawan Handi , Dafrita Ivan Eldes , Trisianawaty Eka , Sari Mustika , Sulistiany Henny , Nawawi Nawawi
Published: September 2020

Kegiatan pengabdian pada masyarakat ini bertujuan untuk meningkatkan pemahaman guru tentang implementasi model Double Critical Technology Society (DCTS) pada pembelajaran IPA. Sasaran kegiatan ini adalah guru-guru IPA SMP dan SMA yang berada pada wilayah Kabupaten Kapuas Hulu, yang berjumlah 60 orang.  Kegiatan ini dilakukan dengan metode ceramah, diskusi, dan tanya jawab.  Materi sosialisasi terdiri dari pembelajaran IPA, pembelajaran berbasis konstruktivisme, serta pembelajarn IPA menggunakan model DCTS.  Berdasarkan hasil sosialisasi yang dilaksanakan menunjukkan peningkatan pengetahuan dan pemahaman peserta tentang implementasi pembelajarn IPA berbasis Konstruktivisme menggunakan model DCTS. Selain itu kegiatan berjalan lancar dan besarnya antusias peserta terhadap kegiatan ini. Melalui kegiatan sosialisasi ini peserta dapat menggunakan model DCTS sebagai sebuah strategi pembelajaran IPA di kelas.This community service activity aims to increase teachers' understanding of the implementation of the Double Critical Technology Society (DCTS) model in science learning. The target of this activity is the science teachers of SMP and SMA in the Kapuas Hulu district, totalling 60 people. This activity is carried out through lectures, discussions, and questions and answers. The socialization materials consisted of science learning, constructivism-based learning, and science learning using the DCTS model. Based on the results of the socialization carried out, it showed an increase in participants' knowledge and understanding of the implementation of constructivism-based science learning using the DCTS model. Also, the activity ran smoothly, and the participants were enthusiastic about this activity. Through this socialization activity, participants can use the DCTS model as a science learning strategy in the classroom.
Developing a Need-Based Pedagogy of English Curriculum
Authors: Devupalli Vishwa Prasad
Published: September 2020

This book is a research study, which deals with firstly, the English language proficiency levels of Pedagogy of English student-teachers and practicing government English teachers. Secondly, the knowledge base – pedagogical knowledge, content knowledge, and pedagogical content knowledge – the teachers should have. Thirdly, it reflects on the efficacy of the present preservice B.Ed. Pedagogy of English curriculum to address the needs of the student-teachers. Fourthly, the perceptions they hold regarding effective preservice B. Ed. Pedagogy of English, and finally, posit a Pedagogy of English curriculum based on the analyses to make the content more beneficial to Pedagogy of English student-teachers.
Revisiting Urbanisation Pattern amid COVID-19 Pandemic in India
Authors: Patidar Hemant , Chothodi Satheesh
Published: September 2020

The COVID-19 pandemic, from its beginning in India on 30 January 2020, has caused over 3.7 million cases of illness and claimed over 66 thousand deaths as of 1 September2020. The large metropolitan cities have been the major hotspots of COVID-19 pandemic. The peculiar urbanisation patterns are crucial in spreading COVID-19 in India. This study attempts to highlight how urbanisation patterns increase the vulnerability of COVID-19 spread in India. The higher density, urban sprawl and associated intra-urban commuting, large slum population, inadequate water, sanitation and housing conditions along with homelessness are found to catalyse the vulnerability of COVID-19 spread in urban areas. The existing public health infrastructure in the country is found to be inadequate with respect to the increasing demand. Efforts to contain the spread are being made; nonetheless, the rapid increase in the cases of illness and deaths from COVID-19 has inflated the challenges for administration and citizens. Rapid enhancement in health infrastructure and health personnel must be made along with strict adherence to the measures of quarantine, social distancing and hygiene for the citizens are of utmost response to the decrease the spread.
Muslim Women’s Haji Ali Movement in Mumbai: Reimagining Feminism and Piety in Islam
Authors: Sur Esita
Published: September 2020

Muslim women’s engagement with Islam through Haji Ali Movement in Mumbai highlights an interesting as well as conflicting encounters between Islam, feminism, and women’s rights. It not only disturbs the quintessential images of them but also opens up an array of possibilities to comprehend that Muslim women can develop their own critique of religion and cultural practices from within. The study argues that the Muslim women’s Haji Ali movement or the mosque movement offers a surprising trade-off between Islam, feminism, and women’s rights by challenging the long-established idea that these are mutually exclusive entities and the distance cannot be bridged. Therefore, the study not only tries to find out the origin, nature, and unique characteristics of the movement but also the new ways of exploring the dialogue between Muslim women’s religious subjectivity, rights, and feminism in India.
Cultural Hegemony and Victimisation of Bedia Women in Central India
Authors: Rana Usha
Published: September 2020

Italian philosopher Antonio Gramsci first coined the term “hegemony” and also elaborated on cultural hegemony. It is a common perception that cultural powers and organisations are hegemonic-centred, resulting in a network of invisible powers. Hegemonic power processes are an integral part of daily social and cultural practices that help to perpetuate power relations. The repercussions of hegemony can be seen in various aspects of society, such as caste, class, ethnicity, occupation, gender, tradition, etc. This paper enlightens on the gendered hegemonic cultural practice of prostitution (sex work) as a traditional institution in the Bedia community. The intensive fieldwork in Habla hamlet, a sub-village of Luhari village (village assembly) of the Bedia community in Sagar district in Madhya Pradesh, India, was conducted to reveal the hegemonic practices in the community. Forty people aged between 50 to 60 years have been interviewed for this study. Twenty females and twenty males were selected for data collection, and observations had been made in the hamlet to understand hegemony through social institutions.

Moreover, we have found that the male members are alert to the preservation of the purity and chastity of their wives but compelled their sisters and daughters, with the support of social institutions, to remain unmarried and take up prostitution (sex work). In particular, Bedias' hegemonic traditional cultural behaviour plays an essential role in the continuation of discrimination against Bedia women. Additionally, we explore the mechanism of this hegemonic power through the role of gender, patriarchy, false consciousness, emotions, power of common sense, ideology, and history, which have been responsible for the victimisation of Bedia women for a long time.
Long-term measurements of aerosol optical properties and radiative forcing (2011-2017) over Central Amazonia
Authors:   Federal University of Pará, UFPA, Belém 66075-110, Brazil. Universidade Federal do Pará Instituto de Geociências - Campus Universitário do Guamá, s/n - Universitário, Belém - PA, 66075-110, Palácios Rafael da Silva , Artaxo Paulo ,   University of São Paulo, USP, São Paulo 05508-090, Brazil, Cirino Glauber Guimarães ,   Federal University of Pará, UFPA, Belém 66075-110, Brazil, Nakale Valeria ,   Federal University of Pará, UFPA, Belém 66075-110, Brazil, Morais Fernando Gonçalves ,   University of São Paulo, USP, São Paulo 05508-090, Brazil, Rothmund Lucas Douglas ,   Federal University of Mato Grosso, UFMT, Cuiabá 78060-900, Brazil, Biudes Marcelo Sacardi ,   Federal University of Mato Grosso, UFMT, Cuiabá 78060-900, Brazil, Machado Nadja Gomes ,   Federal Institute of Mato Grosso, IFMT, Cuiabá 78050-560, Brazil, Curado Leone Francisco Amorim ,   Federal University of Mato Grosso, UFMT, Cuiabá 78060-900, Brazil, Marques João Basso ,   Federal University of Mato Grosso, UFMT, Cuiabá 78060-900, Brazil, Nogueira José de Souza ,   Federal University of Mato Grosso, UFMT, Cuiabá 78060-900, Brazil
Published: September 2020

The Amazon region is one of the most pristine continental areas whose concentrations of atmospheric trace gases and aerosol particles are very low, mainly in the wet season. This study provides observational results of aerosol optical and radiative characteristics in situ as well as atmospheric columnar at a pristine forest in Central Amazonia. Spectral variation of the aerosol properties (aerosol optical depth [AOD], single scattering albedo [SSA], and asymmetry parameter [AP]) was evaluated using the AErosol RObotic NETwork (AERONET) data. The SSA values under natural atmospheric column conditions (AERONET) were compared to the SSA values calculated with in situ measurements. The values of shortwave aerosol radiative forcing (SWARF) on top of the atmosphere (TOA) and the surface (SUR) were estimated using the SBDART model and were validated with the AERONET values with regression analysis. SWARF had a high correlation to TOA (0.97) and SUR (0.92), including dry and wet seasons. Monthly, seasonal and annual mean values of SWARFTOA and SWARFSUR were negative while SWARFATM values were positive. SWARFTOA was –9.18 ± 2.80 W m–2 and SWARFSUR was –20.77 ± 5.04 W m–2 in the dry season, inducing a heating rate (HR) of 0.37 ± 0.13 K.day–1. This study showed that, for a long series of measurements, the effects caused by aerosols on the radiative flux in the pristine forest of Central Amazonia were of the order of SWARFTOA of –3.66 ± 1.59 W m–2 and SWARFSUR of –11.86 ± 2.35 W m–2 during the wet season
Vorticity and Thermodynamics in a Gulf of Mexico Atmospheric River
Authors:   New Mexico Institute of Mining and Technology801 Leroy PlaceSocorro, NM 87801, Martínez-Claros Jose , Raymond David J. ,   New Mexico Institute of Mining and Technology801 Leroy PlaceSocorro, NM 87801, Fuchs-Stone Željka ,   New Mexico Institute of Mining and Technology801 Leroy PlaceSocorro, NM 87801
Published: September 2020

This paper examines the interaction of tropical moisture with an atmospheric river. The analysis of this paper is focused mainly on dropsonde data collected during the fifth day of the Convective Processes Experiment (CPEX). An area of interest is chosen over the central Gulf of Mexico, where the remnant moisture of the tropical system Beatriz penetrated from the Eastern Pacific after making landfall in the western coast of Mexi-co. Results in this study show an eastward-tilting pattern of enhanced mid-level vorticity, coupled with high saturation fraction and low instability index in the predominantly stratiform regime present in the region. An inverse relation between saturation fraction and instability index, as indicated by moisture quasi-equilibrium (MQE), is found in a previously-dominant convective regime. Strong vertical shear signals that the vorticity pattern within this stratiform system is being advected poleward into mid-latitudes. Poleward-moving moisture plumes in narrow channels called atmospheric rivers (ARs) are observed during the mission. We provide insights into vorticity and MQE as conceptual tools to characterize the moisture mechanism of atmospheric rivers near the tropics, where the physical processes behind these river-like structures are less well-understood.
Contemporary and Systematic Review of Smartphone Apps for Tinnitus Management and Treatment
Authors: Mehdi Muntazir , Dode Albi , Pryss Rüdiger , Schlee Winfried , Reichert Manfred , Hauck Franz J.
Published: September 2020

Tinnitus is a complex and heterogeneous psycho-physiological disorder responsible for causing a phantom ringing or buzzing sound albeit the absence of an external sound source. It has a direct influence on affecting the quality of life of its sufferers. Despite being around for a while, there hasn’t been a cure for tinnitus, and the usual course of action for its treatment involves use of tinnitus retaining and sound therapy, or Cognitive Behavioral Therapy (CBT). One positive aspect about these therapies is that they can be administered face-to-face as well as delivered via internet or smartphone. Smartphones are especially helpful as they are highly personalized devices, and offer a well-established ecosystem of apps, accessible via respective marketplaces of differing mobile platforms. Note that current therapeutic treatments such as CBT have shown to be effective in suppressing the tinnitus symptoms when administered face-to-face, their effectiveness when being delivered using smartphones is not known so far. A quick search on the prominent market places of popular mobile platforms (Android and iOS) yielded roughly 250 smartphone apps offering tinnitus-related therapies and tinnitus management. As this number is expected to steadily increase due to high interest in smartphone app development, a contemporary review of such apps is crucial. In this paper, we aim to review scientific studies validating the smartphone apps, particularly to test their effectiveness in tinnitus management and treatment. We use the PRISMA guidelines for systematic identification of studies on major scientific literature sources and delineate the outcomes of identified studies.
Global Dynamics of a Higher Order Difference Equation with Quadratic Term
Authors: Taşdemir Erkan
Published: September 2020

In this paper, we investigate the dynamics of following higher order difference equation x_{n+1}=A+B((x_{n})/(x_{n-m}²)) with A,B and initial conditions are positive numbers. Especially we study the boundedness, periodicity, global asymptotically stability and rate of convergence of related higher order difference equations.
Exploring COVID-19 Daily Records of Diagnosed Cases and Fatalities Based on Simple Non-parametric Methods
Authors: Diebner Hans H. , Timmesfeld Nina
Published: September 2020

Based on comprehensible non-parametric methods, estimates of crucial parameters that characterise the COVID-19 pandemic with a focus on the German epidemic are presented. Where appropriate, the estimates for Germany are compared with the results for six other countries (FR, IT, US, UK, ES, CH) to get an idea of the breadth of applicability and a relational understanding. Thereby, only prevalence data of daily reported new counts of diagnosed cases and fatalities provided by the ECDC are used. Where appropriate, the results are compared with conclusions drawn from using the dataset provided by the RKI. Drawing on uncertain a priori knowledge is avoided. Specifically, we present estimates for the duration from diagnosis to death being 13 days for Germany and about 2 days for Italy as the extremes. Furthermore, based on the knowledge of this time lag between diagnoses and deaths, properly delayed asymptotic as well as instantaneous fatality-case ratios are calculated having superiority compared to the commonly published case-fatality rate. The median of the time series of the instantaneous fatality-case ratio with proper delay of 13-days between cases and deaths for Germany turns out to be 0.024. Asymptotic values are presented for other countries with France ranking highest with a fatality-case ratio of almost 0.2 at its peak. The basic reproduction number, R_0, for Germany is estimated to be between 2.4 and 3.4. The uncertainty stems from uncertain knowledge of the generation time. A delay autocorrelation shows resonances at about 4 days and 7 days, where the latter resonance is at least partially attributable to the sampling process with weekly periodicity. The calculation of the basic reproduction number is based on an evaluation of cumulative numbers of cases yielding time-dependent doubling times as an intermediate step. This allows to infer to the reproduction number during the early phase of onset of the epidemic. In a second approach, the instantaneous basic reproduction number is derived from the incident (counts of new) cases and allows, in contrast to the first version, to infer to the temporal behaviour of the reproduction number during the later epidemic course. To conclude, by avoiding complicated parametric models we provide insights into basic features of the COVID-19 epidemic in an utmost transparent and comprehensible way.
The Effect of Students’ Experience with the Transition from Primary to Secondary School on Self-Regulated Learning and Motivation
Authors: Uka Ana , Uka Arban
Published: September 2020

Transition from primary to secondary school is more successful when students’ learning is consistent. Students are also more likely to enjoy the school, engage with learning, and have a high academic achievement in the secondary school when they feel motivated. This is a critical aspect especially in cases when global pandemics situations allow only the online schooling opportunity. Students that are away from school lack the traditional sources of motivation and self-regulated learning skills, thus research is needed to identify other important factors that can be developed in remote settings. The aim of this study was to find out how students perceive their experience with the transition from primary to secondary school and how such a transition influences students’ self-regulated learning (SRL) and motivation. Self-reported data were collected during the COVID-19 breakout from a total of N=80, 6th and 7th grade students aged 12-14 years old. Results showed that students had a successful transition, especially when they are supported by their parents and teachers. Next, Bivariate Pearson Correlation analysis indicated that students’ perceptions about their experience with the transition from primary to secondary school and their self-regulated learning and motivation are significantly correlated. No gender differences were found among all main study variables.
Pinacolone-Alcohol Gas-Phase Solvation Balances as Experimental Dispersion Benchmarks
Authors: Zimmermann Charlotte , Fischer Taija L. , Suhm Martin A.
Published: September 2020

The influence of distant London dispersion forces on the docking preference of alcohols of different size between the two lone electron pairs of the carbonyl group in pinacolone is explored by infrared spectroscopy of the OH stretching fundamental in supersonic jet expansions of 1:1 solvate complexes. Experimentally, no pronounced tendency of the alcohol to switch from the methyl to the bulkier tert-butyl side with increasing size is found. In all cases, methyl docking dominates by at least a factor of two, whereas DFT-optimized structures suggest a very close balance for the larger alcohols, once corrected by CCSD(T) relative electronic energies. Together with inconsistencies when switching from a C4 to a C5 alcohol, this points at deficiencies of the investigated B3LYP and in particular TPSS functionals even after dispersion correction, which cannot be blamed on zero point energy effects. The search for density functionals which describe the harmonic frequency shift, the structural change and the energy difference between the docking isomers of larger alcohols to unsymmetric ketones in a satisfactory way is open.
Implementing WHO Guidance on Conducting and Analysing Vaccination Coverage Cluster Surveys: Two Examples from Nigeria
Authors: Wagai John Ndegwa , Rhoda Dale A. , Prier Mary L. , Trimner Mary Kay , Clary Caitlin , Oteri Joseph , Okposen Bassey , Adeniran Adeyemi , Danovaro-Holliday M. Carolina , Cutts Felicity T.
Published: September 2020

In 2015, the World Health Organization substantially revised its guidance for vaccination coverage cluster surveys (revisions were finalized in 2018) and has since developed a set of accompanying resources, including definitions for standardized coverage indicators and software to calculate them. In addition to tabular presentations of coverage by vaccine and age group, the guidance document and software (named the Vaccination Coverage Quality Indicators - VCQI) – provide insight into crude coverage versus valid doses, vaccination timeliness, missed opportunities for simultaneous vaccination, and vaccination campaign coverage stratified by several parameters, including the number of previous doses received. The VCQI software furnishes several helpful ways to visualize survey results. The current WHO survey guidance was used to design and conduct two nationally representative vaccination coverage surveys in Nigeria – one to assess routine immunization and one to measure post campaign coverage. The primary analysis for both surveys was conducted using VCQI. This paper describes those surveys and highlights some of the analyses that are facilitated by the new resources.
Assessing Automated Machine Learning Service to Detect COVID-19 from X-Ray and CT Images: A Real-Time Smartphone Application Case Study
Authors: Mustafiz Mohammad Razib , Mohsin Khaled
Published: September 2020

AI is leveraging all aspects of life. Medical services are not untouched. Especially in the field of medical image processing and diagnosis. Big IT and Biotechnology companies are investing millions of dollars in medical and AI research. The recent outbreak of SARS COV-2 gave us a unique opportunity to study for a non interventional and sustainable AI solution. Lung disease remains a major healthcare challenge with high morbidity and mortality worldwide. The predominant lung disease was lung cancer. Until recently, the world has witnessed the global pandemic of COVID19, the Novel coronavirus outbreak. We have experienced how viral infection of lung and heart claimed thousands of lives worldwide. With the unprecedented advancement of Artificial Intelligence in recent years, Machine learning can be used to easily detect and classify medical imagery. It is much faster and most of the time more accurate than human radiologists. Once implemented, it is more cost-effective and time-saving. In our study, we evaluated the efficacy of Microsoft Cognitive Service to detect and classify COVID19 induced pneumonia from other Viral/Bacterial pneumonia based on X-Ray and CT images. We wanted to assess the implication and accuracy of the Automated ML-based Rapid Application Development (RAD) environment in the field of Medical Image diagnosis. This study will better equip us to respond with an ML-based diagnostic Decision Support System(DSS) for a Pandemic situation like COVID19. After optimization, the trained network achieved 96.8% Average Precision which was implemented as a Web Application for consumption. However, the same trained network did not perform like Web Application when ported to Smartphone for Real-time inference, which was our main interest of study. The authors believe, there is scope for further study on this issue. One of the main goals of this study was to develop and evaluate the performance of AI-powered Smartphone-based Real-time Applications. Facilitating primary diagnostic services in less equipped and understaffed rural healthcare centers of the world with unreliable internet service.
Self-Quantification Systems to Support Physical Activity: From Theory to Implementation Principles
Authors: Dulaud Paul , Di Loreto Ines , Mottet Denis
Published: September 2020

Since the emergence of the quantified self movement, users aim at health behavior change, but only those who are sufficiently motivated and competent with the tools will succeed. Our literature review shows that theoretical models for quantified self exist but they are too abstract to guide the design of effective user support systems. Here, we propose principles linking theory and implementation to arrive at a hierarchical model for an adaptable and personalized self-quantification system for physical activity support. We show that such a modeling approach should include a multi-factors user model (activity, context, personality, motivation), a hierarchy of multiple time scales (week, day, hour), and a multi-criteria decision analysis (user activity preference, user measured activity, external parameters). Although the implementation still raises many challenges, principles linking theory and implementation should facilitate the design of effective self-quantification system aimed at physical activity increase, and more widely for behavior change.
DetR DB: A Database of Ionizing Radiation Resistance Determinants
Authors: Ryabova Alina , Kozlova Olga , Kadirov Azat , Gusev Oleg , Shagimardanova Elena
Published: September 2020

Nuclear pollution is an urgent environmental issue as a consequence of rapid industrialization and nuclear accidents in the past. Remediation of nuclear polluted sites using microbial vital activity (bioremediation) is a promising approach to recover contaminated areas in an environmentally friendly and cost-saving way. At the same time, the number of known bacterial and archaeal species able to withstand extremely high doses of ionizing radiation is steadily growing every year, together with growing knowledge about mechanisms of radioresistance. This opens up new opportunities for developing new biotechnological solutions. However, these data are often not systemized and it can be difficult to access. Here, we present the Determinants of Radioresistance Database, or DetR DB (http://extremebiolab.com/detr-db/), gathering a comprehensive catalog of radioresistant microbes and their molecular and genetic determinants of enhanced ionizing radiation tolerance. The database provides search tools including taxonomy, common gene name, and BLAST. DetR DB will be a useful tool for research community by facilitating the extraction of the necessary information to help further analysis of radiation-resistant mechanisms.
BARD1 and Breast Cancer: The Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women
Authors: Śniadecki Marcin , Brzeziński Michał , Darecka Katarzyna , Klasa-Mazurkiewicz Dagmara , Poniewierza Patryk , Krzeszowiec Marta , Kmieć Natalia , Wydra Dariusz
Published: September 2020

Current oncological developments are based on improved understanding of genetics, and especially the discovery of genes whose alterations affect cell functions with consequences for the whole body. Our work is focused on the one of these genes, the BARD1 and its oncogenic role in breast cancer. Most importantly, the study points to new avenues in the treatment and prevention of the most frequent female cancer based on BARD1 research. The BARD1 and BRCA1 proteins have similar structures and functions, and they combine to form the new molecule BARD1-BRCA1 heterodimer. The BARD1-BRCA1 complex is involved in genetic stabilization at the cellular level. It allows to mark abnormal DNA fragments by attaching ubiquitin to them. In addition, it blocks (by ubiquitination of RNA polymerase II) the transcription of damaged DNA. Ubiquitination, as well as stabilizing chromatin, or regulating the number of centrosomes, confirms the protective cooperation of BARD1 and BRCA1 in the stabilization of the genome. The overexpression of the oncogenic isoforms BARD1β and BARD1δ permit cancer development. The introduction of routine tests, for instance, to identify the presence of the BARD1β isoform, would make it possible to detect patients at high risk of developing cancer. On the other hand, introducing BARD1δ isoform blocking therapy, which would reduce estrogen sensitivity, may be a new line of cancer therapy with potential to modulate responses to existing treatments. It is possible that the BARD 1 gene offers new hope for improving breast cancer therapy.
Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees During the COVID-19 Pandemic
Authors: Middleton Matthew , Somerset Sarah , Evans Catrin , Blake Holly
Published: September 2020

Background: HIV poses a threat to global health. With effective treatment options available, education and testing strategies are essential in preventing transmission. Text messaging is an effective tool for health promotion and can be used to target higher risk populations. This study reports on the design, delivery and testing of a mobile text messaging SMS intervention for HIV prevention and awareness, aimed at adults in the construction industry and delivered during the COVID-19 pandemic. Method: Participants were recruited at Test@Work workplace health promotion events (21 sites, n=464 employees), including health checks with HIV testing. Message development was based on a participatory design and included a focus group (n=9) and message fidelity testing (n=291) with assessment of intervention uptake, reach, acceptability, and engagement. Barriers to HIV testing were identified and mapped to the COM-B behavioural model. 23 one-way push SMS messages (19 included short web links) were generated and fidelity tested, then sent via automated SMS to two employee cohorts over a 10-week period during the COVID-19 pandemic. Engagement metrics measured were; opt-outs, SMS delivered/read, number of clicks per web link, and four two-way pull messages exploring repeat HIV testing, learning new information, perceived usefulness and behaviour change. Results: 291 people participated (68.3% of eligible attendees). A total of 7,726 messages were sent between March and June 2020, with 91.6% successfully delivered (100% read). 12.4% of participants opted out over 10 weeks. Of delivered messages, links were clicked an average of 14.4%, max 24.1% for HIV related links. The number of clicks on web links declined over time (r= -6.24, p=0.01). Response rate for two-way pull messages was 13.7% of participants. Since the workplace HIV test offer at recruitment, 21.6% reported having taken a further HIV test. Qualitative replies indicated behavioural influence of messaging on exercise, lifestyle behaviours and intention to HIV test. Conclusion: SMS messaging for HIV prevention and awareness is acceptable to adults in the construction industry, has high uptake, low attrition and good engagement with message content, when delivered during a global pandemic. Data collection methods may need refinement for audience and effect of COVID-19 on results is yet to be understood.
Association of Individual Health Literacy with Preventive Behaviours and Family Well-being during COVID-19 Pandemic: Mediating Role of Family Information Sharing
Authors: Wong Janet Yuen Ha , Wai Abraham Ka Chung , Zhao Shengzhi , Yip Faustina , Lee Jung Jae , Wong Carlos King Ho , Wang Man Ping , Lam Tai Hing
Published: September 2020

Objective: We tested a model of individual health literacy, information sharing with family members, personal preventive behaviours and family well-being during COVID-19 pandemic in Hong Kong. Methods: We analysed data of 1501 randomly selected Chinese adults from a cross-sectional survey in Hong Kong from 9 to 23 April 2020. Individual health literacy, COVID-19 information sharing with family members, preventive behaviours against COVID-19 and family well-being were measured. Structural equation modelling analysis tested the proposed model. Findings: COVID-19 information sharing with family members partially mediated the association between individual health literacy and personal preventive behaviours. The direct effect of .24 was shown and indirect effect through COVID-19 information sharing with family members was small with .03 (Z = 3.66, p < .001). Family well-being was associated with personal preventive behaviours against COVID-19. The model was adjusted for sex, age, and socioeconomic status factors and had good ﬁt with RMSEA = .04, CFI = .98, TLI = .96, and SRMR = .02. Conclusion: COVID-19 information sharing with family members was a partial mediator between individual health literacy and personal preventive behaviours against COVID-19. Strategies for enhancing health literacy and preventive measures against COVID-19 are needed to promote family well-being in the pandemic.
Molecular Characterization and Phylogenetic Analysis of Orf Virus Isolated From Goats in Sokoto Metropolis, Nigeria
Authors: Lawal Nafiu
Published: September 2020

Aim: Despite the endemic nature of contagious ecthyma in Nigeria, there is limited report on the molecular characterization of the isolates responsible for disease outbreaks. The aim of this study was to molecularly characterize ORFV isolated from clinical infections in goats in Sokoto metropolis. Materials and Methods: Seronegative embryonated chicken eggs were used to isolate ORFV via the chorio allantoic membrane (CAM) route according to the established protocol. Viral DNA was extracted from infected CAM and the full coding region of B2L gene was amplified by PCR and subsequently sequenced by Sanger’s method. The nucleotide sequence results were blasted for identification and phylogenetically analyzed using MEGA and Bioedit softwares. Results and Discussion: The results showed that B2L gene sequences of the ORFV UDUS/01/19/More strain showed slight variability (96- 98.7%) with the reference sequences. Our isolate clustered within the same clade with Korean strain signifying a close genetic relationship. Unique amino acid substitutions were noted in our isolate when compared with other references. This is arguably the first genetic characterisation of B2L gene of ORFV circulating in Nigeria. Conclusion: Our study has provided in sight into the genetic diversity of ORFV in the study area. This is crucial for the design of effective vaccines against the disease which are currently lacking in the country.
Anthropometric and Kinematics Determinants of Lunge Velocity and Amplitude in Young Foil Fencers
Authors: Cicchella Antonio , Mocco Alessio
Published: September 2020

The teaching of the lunge technique in fencing is critical in the developmental age. The relations of anthropometrics with kinematics of lunge was studied only in adult fencers, and no study exist in young considering the different level of experience. Our aims were to assess, in young fencers, which factors, between the anthropometric and the kinematics, were mostly connected with lunge performance (speed and excursion) in different genders and expertise levels. Fifteen young fencers participated in this study. Lunge kinematics, anthropometric characteristics and force expressed in vertical jump tests were collected. Maximal lunge velocity resulted mainly correlated with the posterior knee’s extension ((r=0.56, p=0.031). The lunge distance and mean hip velocity were mostly correlated with fencers’ height (r=0.85, p=0.000 and r=0.76, p=0.001) and FFM (r=0.8, p=0.000 and r=0.73, p=0.002). Experts and non-experts show significant differences in fat free mass, area of upper arm, and of thighs (Effect Size = 1,27 – 1,33, p= 0,021-0,035). From our results it emerges that, in this age range, the analysed aspects of lunge performance are mainly correlated with participant’s anthropometry. Moreover, it is already possible in this age span, to find technical differences linked to the experience.
Modelling Variation in Petroleum Products’ Refining Footprints
Authors: Johnson Eric , Vadenbo Carl
Published: September 2020

Energy-related greenhouse gas emissions dominate the carbon footprints of most product systems, and petroleum is one of the main types of energy sources. This is consumed as a variety of refined products – most notably diesel, petrol (gasoline) and jet fuel (kerosene). Refined product carbon footprints are of great importance to regulators, policymakers and environmental decision-makers. For instance, they are at the heart of legislation such as the European Union’s Renewable Energy Directive or the United States’ Renewable Fuels Standard. This study identified 14 datasets that report footprints for the same system, European petroleum refining. For the main refined products – diesel, petrol and jet fuel – footprints vary by at least a factor of three. For minor products, the variation is even greater. Five different organs of the European Commission have estimated refining footprints: for main products these are relatively harmonic; for minor products much less so. The footprint variation is due mainly to differing approaches to refinery modelling, especially regarding the rationale and methods applied to assign shares of the total burden from the petroleum refinery operation to the individual products. Given the economic/social importance of refined products, a better harmony of their footprints would be valuable to their users.
Forest Drought Response Index (ForDRI): A New Combined Model to Monitor Forest Drought in the Eastern United States
Authors: Tadesse Tsegaye , Hollinger David Y. , Bayissa Yared A. , Svoboda Mark , Fuchs Brian , Zhang Beichen , Demissie Getachew , Wardlow Brian D. , Bohrer Gil , Clark Kenneth L. , Desai Ankur R. , Gu Lianhong , Noormets Asko , Novick Kimberly A. , Richardson Andrew D.
Published: September 2020

Monitoring drought impacts in forest ecosystems is a complex process, because forest ecosystems are composed of different species with heterogeneous structural compositions. Even though forest drought status is a key control on the carbon cycle, very few indices exist to monitor and predict forest drought stress. The Forest Drought Indicator (ForDRI) is a new monitoring tool developed by the National Drought Mitigation Center (NDMC) to identify forest drought stress. ForDRI integrates 12 types of data, including satellite, climate, evaporative demand, ground water, and soil moisture, into a single hybrid index to estimate tree stress. The model uses Principal Component Analysis (PCA) to determine the contribution of each input variable based on its covariance in the historical records (2003–2017). A 15-year time series of 780 ForDRI maps at a weekly interval were produced. The ForDRI values at a 12.5km spatial resolution were compared with normalized weekly Bowen ratio data, a biophysically based indicator of stress, from nine AmeriFlux sites. There were strong and significant correlations between Bowen ratio data and ForDRI at sites that had experienced intense drought. In addition, tree ring annual increment data at eight sites in four eastern U.S. national parks were compared with ForDRI values at the corresponding sites. The correlation between ForDRI and tree ring increments at the selected eight sites during the summer season ranged between 0.46 and 0.75. Generally, the correlation between the ForDRI and normalized Bowen ratio or tree ring increment are reasonably good and indicate the usefulness of the ForDRI model for estimating drought stress and providing decision support on forest drought management.
The Application of Catalytic Processes on the Production of Algae-Based Biofuels: A Review
Authors: Zuorro Antonio , García-Martínez Janet B. , Barajas-Solano Andrés F.
Published: September 2020

Over the last decades, microalgal biomass has gained a significant role in the development of different high-end (nutraceuticals, colorants, food supplements, and pharmaceuticals) and low-end products (biodiesel, bioethanol, and biogas) due to rapid growth and high carbon fixing efficiency. Therefore, microalgae are considered a useful and sustainable resource to attain energy security while reducing our current reliance on fossil fuels. From the technologies available for obtaining biofuels using microalgae biomass, thermochemical processes (pyrolysis, HTL, gasification) have proven to be processed with higher viability, because they use all biomass. However, because of the complexity of the biomass (lipids, carbohydrates , and proteins), the obtained biofuels from direct thermochemical conversion have large amounts of heteroatoms (oxygen, nitrogen , and sulfur). As a solution, catalyst-based processes have emerged as a sustainable solution for the increase in biocrude production. This paper's objective is to present a comprehensive review of recent developments on catalyst mediated conversion of algal biomass. Special attention will be given to operating conditions, strains evaluated, and challenges for the optimal yield of algal-based biofuels through pyrolysis and HTL.
Modeling of Conservation Priority Zone for the Helmeted Hornbill (Rhinoplax Vigil) In Silokek Geopark Area, West Sumatra
Authors: Hidayat Rizki Atthoriq , Febriani Natasyah , Hanif Muhammad , Rahman Henzulkifli
Published: September 2020

Helmeted hornbill (Rhinoplax vigil) is a protected wildlife in Indonesia according to enactment no. 5, 1999 about Conservation of Natural Resources and its Ecosystems and Government Regulation no. 9, 1999 about plant and wildlife preservation. Helmeted Hornbill habitats spread in five country regions: Myanmar, Thailand, Malaysia (Malayan Peninsula and Serawak), Brunei, and Indonesia (Sumatra and Borneo). Silokek Geopark which located in Sijunjung Regency, West Sumatra Province, Indonesia is an identified location of Helmeted Hornbill habitat existence. Beside its uniqueness in physics, this bird also have an ecological function as seed dispersal in nature. The utilization of Remote Sensing (RS) technology and and Geographic Information System (GIS) is highly useful in identification the Helmeted Hornbill habitat distribution in this research. Geographic dateset used in this research are Landsat OLI 8 imagery, Shuttle Radar Topographic Model (SRTM), Coordinate points of Helmeted Hornbill existence and location assesment, and other dataset related to administration boundary in Silokek Geopark. This research aims to find conservation priority zone of Helmeted Hornbill in Silokek Geopark. By utilizing Maximun Entropy (MaxEnt) algorithm with finding points and location assessment, we can determine the distribution of Helmeted Hornbill habitat in Silokek Geopark based on habitat likeness. This research produces the model of conservation priority zones in geopark silokek which are distributed in hilly protected forest area and the distributions are concentrated in the center and noth east part of our researc area. This model is highly influenced by forest texture (25.7%), distance of patches (24.3%), and distance of settlement.
An Investigation on the Electrical Activity of the Brain during Fara-Darmani Connection in the Fara-Therapist Population
Authors: Taheri Mohammad Ali , Semsarha Farid , Modarresi-Asem Fateme
Published: September 2020

Mind-body interaction and its manifestations at the brain level has been studied extensively in the field of consciousness research. Fara-darmani Consciousness Field, as claimed by Mohammad Ali Taheri (the founder), is a method of connecting with the Cosmic Consciousness Network through human mind and his brain has a detective role in this process. As a result of this connection, the scanning process of the state of a being, e.g., the health status of the cells and consequently organs is performed. This study was conducted to evaluate the effects of the Fara-darmani Consciousness Field connection on electroencephalogram (EEG) features as an important biomarker of the brain functioning. The results showed that there was a significant increase in the gamma2 frequency band (35-40 Hz) power in the frontal lobe in medial frontal gyrus (BA6) and paracentral lobule (BA31) of the brain during the task condition compared to the rest condition in a Fara-therapist population. Considering the cortical electrical activity of Fara-therapist’s brain during Fara-darmani Consciousness Field connection, characterizing increase in the power of gamma wave and the activity of the areas affecting on memory, attention, perception and default mode network intrinsic activity. This manifestation distinguishes Fara-darmani Consciousness Field connection from other known methods dealing with the mind-body interaction criterion mainly different types of mediation.
Movimentos pendulares e integração regional no leste fluminense
Authors: Passarelli-Araujo Hisrael , De Souza Joseane
Published: September 2020

A pendularidade é uma importante medida para avaliar os processos de integração das cidades e a dinâmica populacional regional. Em 2015, o IBGE identificou a intensificação dos movimentos pendulares entre os municípios do leste fluminense, de Arraial do Cabo a São João da Barra, considerando-os aspectos relevantes da urbanização brasileira. Contudo, pouco se sabe sobre o peso da pendularidade entre esses municípios e o nível de interação que eles estabelecem com Macaé, principal destino dos pendulares na região. Esse trabalho analisa o grau de integração regional do vetor leste fluminense, a partir dos dados censitários de 2000 e 2010. A pendularidade por trabalho e/ou estudo observada em Macaé o coloca em posição de destaque entre os municípios selecionados. Afirmamos, portanto, que Macaé não é apenas uma cidade em movimento, mas também um município potencialmente integrador do mercado de trabalho das demais municipalidades da região. É em torno desse município que o tecido urbano regional tem se reorganizado. Esse estudo pode iluminar novas discussões sobre os processos recentes de urbanização no estado do Rio de Janeiro, sobretudo por se tratar de uma região demograficamente integrada, mas politicamente fragmentada.