bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between Loneliness and Internet Addiction During The COVID-19 Pandemic on Class XI Students of 99 Jakarta Public High School Even Semester in The Academic Year 2021/2022 and Its Review from Islamic View
Authors: Rizki Misae Fattah , Andayani Sri Hastuti
Published: November 2023

When WHO stated that one way to prevent transmission of COVID-19 is social distancing, the Government of Indonesia carried out a large-scale social restriction program (PSBB), namely work from home, distance learning/learning from home (school from home), and carrying out worship activities from home. Those programs can lead to a lack of social interaction in students' social life cause an increase in loneliness during a pandemic. Individuals who feel lonely will look for ways to fill their emptiness, including the internet. The internet can be a place of escape or coping for many lonely individuals that can form an online friendship, which can cause reducing loneliness despite the excessive use that can turn into an addiction. This study aims to determine the relationship between loneliness and internet addiction during the COVID-19 pandemic in Class XI students at SMA Negeri 99 Jakarta in the even semester of the 2021/2022 academic year. This study used an observational study with a cross-sectional that conducted by students at age 15-18 years old. The results of the analysis of the relationship between loneliness and internet addiction show a correlation coefficient (r) = 0.418 and a significance value of 0.000 (p <0.05), which concludes loneliness has a significant effect on internet addiction. This study concludes that there is a positive correlation between the two variables, where the higher the loneliness, the higher the level of internet addiction.
Pengaruh Aktivitas Olahraga Sehari-HariTerhadap Insidensi OA Genu pada Mahasiswa Fakultas Kedokteran Universitas Yarsi Angkatan 2019 dan Tinjauannya Menurut Islam
Authors: Rafi Alaric Casta , Yuliadi Teguh , Istiwara Endy Muhammad
Published: November 2023

Pendahuluan: Osteoarthritis (OA) adalah gangguan kronis sendi sinovial di mana ada pelunakan progresif dan disintegrasi tulang rawan artikular disertai dengan pertumbuhan baru tulang rawan dan tulang pada margin sendi (osteofit), pembentukan kista dan sklerosis di tulang sub-kondral, sinovitis ringan dan fibrosis kapsuler. Salah satu faktor risiko OA adalah kegiatan beban tinggi rutin, yang salah satunya adalah olahraga. Olahraga merupakan aktivitas fisik yang direncanakan, terstruktur, dan bersifat repetitif dengan tujuan mengkondisikan tubuh untuk meningkatkan kesehatan, menjaga kebugaran dan rehabilitasi fisik Banyaknya manfaat aktivitas olahraga tentu menjadikannya salah satu kegiatan fisik yang diminati banyak orang. Akan tetapi kegiatan fisik seperti olahraga seringkali berlibatan dengan menitikberatkan beban pada sendi-sendi extremitas bawah, khususnya pada sendi lutut (genu). Ini berpotensi menimbulkan OA, tidak hanya pada populasi yang berusia, tapi pada populasi muda juga. Mahasiswa sebagai penerus bangsa dan calon populasi produktif harus dihindari dari risiko ini. Tujuan penelitian ini adalah untuk mengetahui pengaruh aktivitas olahraga terhadap insidensi OA pada mahasiswa kedokteran serta tinjauannya menurut Islam.Metode: Jenis penelitian ini berupa survey observasional dengan desain penelitian cross sectional. Kuesioner didistribusikan melalui google form dan dilakukan pada mahasiswa Fakultas Kedokteran Universitas Yarsi angkatan 2019 dengan jumlah sampel sebanyak 160 responden. Analisis data dilakukan secara univariat dan bivariat menggunakan uji regresi linear.Hasil: Rata-rata aktivitas olahraga didapatkan setinggi 702,88 METs, dengan rata-rata insidensi OA berdasarkan WOMAC sejumlah 5,81 poin dari maksimal 96 poin. Berdasarkan hasil uji statistik didapatkan p = 0.186 (p>0.05) yang menunjukkan bahwa tidak terdapat pengaruh yang signifikan dari aktivitas olahraga terhadap insidensi OA Genu pada mahasiswa Fakultas Kedokteran Universitas Yarsi angkatan 2019.Simpulan: Tidak terdapat pengaruh yang bermakna secara statistik antara aktivitas olahraga terhadap insidensi OA Genu.
The Relationship Between Physical Activity and Sleep Duration on The Incidence of Obesity in Children under Five in Central Jakarta and The Review of Islamic Perspective
Authors: Adhitama Astalia Maisya , Mukhtar Diniwati , Sachrowardi Qomariyah , Istiwara Endy Muhammad
Published: November 2023

Introduction: The excessive buildup of fat, known as obesity, can negatively affect health. In 2020, there will be 38.9 million overweight children under the age of five worldwide. 7.8% of toddlers in DKI Jakarta are fat, compared to 7.04% in central Jakarta. A variety of factors cause obesity. The two most important factors are insufficient sleep time and physical exercise.  Methodology: This type of research is quantitative with a cross-sectional design. The study population was toddlers in Sawah Besar District, Central Jakarta, a total of 70 people. Results: The results showed that 33 people (47.1%) were ordinary, four people (5.7%) were at risk of being overweight, three people (4.3%) were fat, and 30 people (42.9%) were obese. Moderate physical activity was found in 15 people (50%) normal and 15 people (50%) obese. At the same time, physical activity is less, with as many as 18 people (45%) ordinary and 22 people (55%) obese. Found adequate sleep duration in 21 people (63.648%) were ordinary, and 12 (36.36%) were obese. At the same time, the rest period is seen in as many as 12 people (32.43%) normal and 25 people (67.57%) obese. P=0.810 and p=0.016 show differences in physical activity and sleep duration in obese toddlers. Conclusion: In toddlers in the Sawah Besar District of Central Jakarta, there is a meaningful association between sleep duration and the incidence of obesity (p=0.016) and no relationship between physical activity and the incidence of obesity (p=0.810) with an Odd Ratio value of 1.222.
The Level of Knowledge of Jatimulya Bekasi Village Residents on the Use of Vitamin C during the Covid 19 Pandemic and According to Islamic Overview
Authors: Nur Syarifah Rana Alifiah , Permana Dharma , Gunawan Andri
Published: November 2023

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The percaution to avoid COVID-19 virus is to take vitamin C to boost the body's immune system. This research is a correlative-descriptive studies, with cross-sectional method in Kelurahan Jatimulya Bekasi in RT 001 and RT 002 RW 013 for residents aged 17-55 years old. Using simple-random sampling method, 123 residents who consumed vitamin C used as respondents with digital questionnaire. The answers from the questionnaire used to group respondents according to their three level categories knowledge of satisfactory, intermediate and low. Descriptive-analysis was conducted to see the characteristics. Data analysis was also carried out by making frequency tables between the level of knowledge in correlation with age, education, and occupation. Based on the analysis of the questionnaire results, it was found that majority of 65 respondents (52.8%) had satisfactory knowledge regarding the use of vitamin C, with characteristics age 17 – 25 years old, had non-medical tertiary education, and work in private sector. Research using the Chi-Square statistical test found that there was a significant correlation between age (p=0,002) with the knowledge of the use of vitamin C. The good knowledge of respondents is received information about the use of vitamin C from health workers, electronic media, packaging Information-content and educational institutions. In Islam overview, gaining knowledge is an obligation as mentioned in Q.S. Ali-Imran (3):190.
The Relationship between Sleep Patterns and the Incidence of Dysmenorrhea in YARSI University Faculty of Medicine Students in 2020-2011 and the Review from an Islamic View
Authors: Catherina Fetricia , Zakiyah Zakiyah , Arifandi Firman
Published: November 2023

Introduction: Dysmenorrhea is pain that is felt in the pelvic area due to menstruation and the production of prostaglandin substances. Dysmenorrhea is caused by many factors, one of which is sleep patterns. This study aims to find out whether there is a relationship between sleep patterns and the incidence of dysmenorrhea in YARSI University Medical Faculty Students Batch 2020-2021 and Reviews According to an Islamic View.Method: This type of research is correlational with a cross sectional approach and the method of determining the sample is purposive sampling. The sample in this study were YARSI University Medical Faculty Students Class of 2020-2021, a total of 97 students. Data collection was carried out using a questionnaire.Result: From the results of statistical analysis, it was found that 5 (5.2%) respondents with good sleep patterns experienced mild to moderate dysmenorrhea. While 92 (94.8%) of respondents with poor sleep patterns experienced mild dysmenorrhea as many as 46 (47.4%), moderate as many as 42 (43.3%) and severe as many as 4 (4.1%). The results of the Chi square test obtained a p value of 0.417 (> 0.05) which indicated that there was no significant relationship between sleep patterns and dysmenorrhea in YARSI University Faculty of Medicine Students class of 2020-2021.Conclusion: There is no significant relationship between sleep patterns and dysmenorrhea in YARSI University Faculty of Medicine Students class of 2020-2021. However, there is an increased risk of mild to moderate dysmenorrhea in respondents who have poor sleep quality.
Correlation of Comorbidities with the Quality of Life Among Pre-Geriatric COVID-19 Survivors in Jakarta Greater Area And Its Review in Islamic Perspective
Authors: Azrina Annisa Nurul , Susilowati RW , Arsyad Muhammad
Published: November 2023

Background: Coronavirus Disease (COVID-19) is a contagious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2) that can affect humans. One of the risk factors, such as comorbidities, caused a significant increase in the mortality rate of COVID-19. Health problems arise in accordance with increased human age, resulting in decreased quality of life. Various aspects can influence the quality of life; general quality of life, health, physical, psychological, social, and environmental. In Islam, humans are perceived as the world's leaders; thus, they must preserve their health. This study aims to analyze the correlation of comorbidities with the quality of life in pre-geriatric survivors of COVID-19 in the Jakarta Greater Area and its review according to the Islamic perspective.Methods: This study utilized the correlational analytical survey design with a cross-sectional approach. Samples were obtained by consecutive sampling technique with a total number of 62 respondents. Data collection was done by filling out an online questionnaire distributed in Google Forms. Independent t-tests and Mann-Whitney testing were used to analyze data.Results: There were no significant differences in quality of life in general health from both groups of pre-geriatric COVID-19 survivors, with and without comorbidities and with a p-value> 0,005 in each domain.Conclusion: There is no correlation between the quality of life to general health condition, physical, psychological, social, and environmental domains to pre-geriatric COVID-19 survivors in both groups with and without comorbidities.
Relationship Between Change of Waist and Hip Circumferences Due To Online Lectures in Medical Students of Yarsi University Class of 2019 and The Review in Islamic Perspectives
Authors: Amalia Nadia Rizki , Sofwan Achmad , Karimullah Karimulloh
Published: November 2023

Abstract written in English maximum 250 words. Abstract is made concise and clear with italic format. Abstract contains Online lectures during the COVID-19 pandemic are implemented to reduce face-to-face activities. Online lectures have various impacts on students, one of them is reduced physical activity. The result of online lectures is a change in waist circumference and hip circumference. This may cause obesity in students. The objective of this study is to show the changes that occur and the relationship between changes in the shape of the hip and waist circumference due to online lectures in Medical Students of YARSI University Class of 2019. This study used a descriptive analytic study with a Paired t-Test research design. The sample size used in this study is 72 students. Sampling method used in this study is a purposive sampling method. The research instrument is a sheet recording the waist and hip circumferences measured by a tape and repeated 2 times. Statistical analysis was performed by univariate test and bivariate Paired t-Test. Islamic views regarding changes in the body, one of which is waist and hip circumference due to lifestyle, will be held accountable later. Allah commands His people to be responsible for the body that has been given and take good care of it.
Pengaruh Tatalaksana Farmakologi dengan Perjalanan Klinis Pasien Anak COVID-19 di RSPAD Gatot Soebroto dan Tinjauannya Menurut Pandangan Islam
Authors: Insani Bella Khoiriyah , Andayani Sri Hastuti
Published: November 2023

Pendahuluan: COVID-19 (Coronavirus Disease 2019) adalah penyakit yang disebabkan oleh virus korona yang disebut SARS-CoV-2. WHO pertama kali mengetahui virus baru ini pada 31 Desember 2019 kemudian diberi nama Severe Acute Respiratory Syndrome Coronavirus (SARS-COV 2). Berdasarkan Panduan Klinis Tatalaksana COVID-19 pada Anak yang dikeluarkan oleh IDAI, salah satu tatalaksana farmakologi yang diberikan kepada pasien adalah pemberian antiviral, diantaranya Oseltamivir, Favipiravir, dan Remdesivir. Oleh karena itu penting untuk mengetahui pengaruh antara tatalaksana farmakologi (pemberian antivirus) dengan perjalanan klinis (ARDS) pasien anak COVID-19 dari pandangan kedokteran dan Islam.         Metodologi: Jenis penelitian ini adalah observasional analitik dengan desain penelitian case control. Sampel dalam penelitian ini adalah seluruh pasien anak COVID-19 yang dirawat inap RSPAD Gatot Soebroto selama periode Januari – Desember 2021 yang memenuhi kriteria inklusi sebanyak 99 responden. Pengumpulan data dilakukan dengan menggunakan data sekunder berupa rekam medis yang diolah dengan menggunakan SPSS.         Hasil: Hasil penelitian ini didapatkan dari 99 responden, yang terdiri dari responden yang diberi antiviral dan responden yang tidak diberi antiviral yang memiliki saturasi oksigen <95% dan >95%. Berdasarkan hasil analisis bivariat  dengan analisis Spearman didapatkan nilai p-value sebesar 0,759 (>0.05), maka p-value bernilai lebih besar sehingga dapat dikatakan bahwa H0 diterima yang artinya tidak terdapat adanya hubungan yang bermakna antara tatalaksana farmakologi dengan perjalanan klinis pasien anak COVID-19 di RSPAD Gatot Soebroto.                 Kesimpulan: Tidak terdapat adanya hubungan signifikan antara tatalaksana farmakologi dengan perjalanan klinis pasien anak COVID-19 di RSPAD Gatot Soebroto
The Relationship between Fast Food Consumption and the Incidence of Obesity in Students of SMA Negeri 3 Subang and Its Review According to Islamic Views
Authors: Ramadani Fachmi , Jannah Fathul
Published: November 2023

Unhealthy and low quality food is what makes up the majority of fast food. Halal and good quality food and drinks are recommended in Islam. These foods and beverages should not only satisfy hunger but also bring health benefits to consumers in the short and long term. Consuming excess fast food can interfere with and damage health such as, the body becomes fat or obese and the emergence of various cardiovascular diseases. Researchers at SMA Negeri 3 Subang began using a quantitative cross-sectional analytic observational methodology to establish a causal relationship between their students' love of fast food and the increasing obesity rate in their school. Univariate and bivariate statistics were used to analyze the data. The results showed that the highest body mass index of SMA Negeri 3 Subang students was normal with a total of 41 (42.3%) students, while the body mass index for obesity was 19 (19.6%) students. 54 (55.7%) students of SMA Negeri 3 Subang have a habit of frequently consuming fast food, while 43 (44.3%) of other students have a habit of rarely consuming fast food. The research data showed that there was no significant relationship between fast food consumption and the incidence of obesity in SMA Negeri 3 Subang students. (p-value = 0.138). The Islamic view regarding the relationship between fast food consumption and obesity is that Islam instructs people to eat halal, thayyib and not excess food
Relationship between Physical Activity with Sleep Quality in The Pandemi Time of Yarsi University Students Class of 2020 and The Review According to The Islamic Point of View
Authors: Maulana Ari Fajar , Pusparini Miranti , Astiwara Endy Muhammad
Published: November 2023

Sleep is one of the basic human needs, meaning that humans naturally need sleep as a daily necessity. Sleep quality is influenced by many things, one of which is physical activity. The Covid-19 pandemic has made students spend a lot of time at home which allows them not to do physical activity. This study aims to determine the relationship between physical activity and sleep quality of students at the medical faculty of YARSI University. This research is a correlational study with a cross sectional design. The population of this study were YARSI University medical faculty students class of 2020. The sampling technique was purposive sampling. The total sample is 142 students. Physical activity instruments using the Global Physical Activity Questionnaire and the Pittsburgh Quality Sleep Index as sleep quality instruments. Data analysis using Chi Square with a confidence level of 95%. The results of the chi square analysis obtained a value (p) = 0.013 and Odd Ratio (OR) = 3.097. These results indicate that there is a significant relationship (p<0.05) between physical activity and sleep quality. Subjects who are active in physical activity have the opportunity to get good quality sleep 3,097 times higher than subjects who are not active.
Analisis Manfaat E-Booklet dalam Mengedukasi Masyarakat tentang Hipertensi di Rumkitban JS/00.08 Bintaro Jakarta Selatan
Authors: Anggraini Wiwik , Agustina Citra Fitri , Sari Wening , Istiwara Endy Muhammad
Published: November 2023

World Health Organization (WHO) mengestimasikan prevalensi hipertensi secara global sebesar 22% dan kurang dari seperlima yang melakukan upaya pengendalian terhadap tekanan darah. Kepatuhan diet dan minum obat anti hipertensi, serta modifikasi lingkungan merupakan hal penting yang dapat mengontrol hipertensi. Pemberian edukasi dapat meningkatkan pemahaman dan kesadaran untuk mengikuti manajemen hipertensi yang disarankan. Penelitian ini bertujuan untuk menilai pengetahuan dan sikap responden setelah pemberian edukasi. Metode penelitian adalah Quasi Experimental denngan one group pretest-posttest design. Subyek penelitian adalah masyarakat di Rumkitban JS/08.00 Bintaro Jakarta Selatan dengan jumlah sampel 55 orang dari total populasi berjumlah 120 orang. Hasil penelitian didapatkan demografi responden dominan perempuan (69,1%), usia lansia (89,1%), memiliki pekerjaan (61,8%), penghasilan dominan di bawah UMR (60,0%), dengan tingkat pendidikan dominan (SMA 947,3%). Frekuensi pengetahuan menunjukkan terjadi peningkatan nilai rerata dari 61,63 menjadi 79,09, nilai rerata sikap responden dari 36,74 menjadi 41,57 dan persepsi responden tentang E-booklet hipertensi baik. Berdasarkan hasil tersebut dengan menggunakan uji Wilcoxon dapat disimpulkan terdapat hubungan antara E-Booklet dengan meningkatnya pengetahuan dan perubahan sikap.
Implementation of Worship and Religious Preservation Obligations in Inpatients at YARSI Hospital
Authors: Angelia Nidya Rhenatama , Rifqatussa'adah Rifqatussa'adah , Jannah Fathul
Published: November 2023

According to WHO, healthy involves a state of complete well-being which includes four dimensions: physical, mental, social and spiritual. A person's level of spirituality can affect his quality of life. In relation to the healing process, spirituality can be explained by holistic concepts and services in nursing. YARSI Hospital itself has conducted an assessment of the spiritual aspect among other Islamic hospitals entitled "Spiritual Friendly" or can be mentioned with its motto that preserves religion (hifdz Addin), such as the obligation of worship and religious preservations obligations. This study aims to find out an overview of the implementation of spiritual aspects in inpatients at YARSI Hospital and its review in Islam. This study used analytical survey research with a cross-sectional research design. The sample was established using purposive sampling technique. The population of this study was inpatients at YARSI Hospital for the period of May – December 2021 with its collection using the YARSI Hospital Information System instrument with a sample of 1703 patients. The results showed that the majority of patients were women. The results of the statistical test also showed that gender was related to worship obligations (p=0.003) and religious actions (p=0.000), age with religious actions (p=0.000), length of hospitalization with worship obligations and religious actions (p=0.000). Meanwhile, at the age of worship obligations, no significant relationship was found. The conclusion in this study is that the nature of disease in Islam is the best test given by Allah Almighty. A good believer when given an exam will have to respond sincerely, patiently, and seek treatment.
Literature Review : The Effects of Antioxidant Saponins in Herbal Plants on Testicular Histology of Rats with Diabetes Mellitus and The Review of Islamic Perspective
Authors: Persada Jean Kharismatik , Widayanti Etty , Royhan Aan
Published: November 2023

Introduction: Diabetes mellitus is a metabolic disorder. Diabetes mellitus can cause a decrease in sperm count, sperm motility, testosterone hormone, erectile ability, libido and testicular weight. Antidiabetic drugs consumed long-term can cause side effects; therefore, alternative treatment is needed using herbal medicinal plants. Saponins in plants are a complex class of complex natural compounds with a large molecular mass, namely steroid or triterpenoid aglycones with one or more sugar/glycoside chains. Saponins function as antioxidants. This study aims to determine the effect of saponins as one of the antioxidants on the testicular organs of rats (Rattus norvegicus) Wistar strain-induced Streptozotocin. Methods: This study used the Literature Review method with a narrative literature review type. The data collection technique uses a search for several research databases through Google Scholar and Mendeley. This research has four journals that will review. Results: The results showed that herbal plants have bioactive compounds such as flavonoids, alkaloids, terpenoids, tannins, and saponins that have antidiabetic effects with different mechanisms in reducing blood glucose levels repairing damage to testicular tissue of diabetes mellitus rats. Conclusion: Antioxidant saponins in herbal plants influence improving and supporting the repair of testicular histology damage in diabetic cases. Allah SWT grows a wide variety of plants that have enormous benefits for humans, including food and medicine, because Allah SWT created various kinds of plants with multiple uses.
Pengaruh Latihan Jump Rope terhadap Skor Harvard Step Test pada Mahasiswa Fakultas Kedokteran Universitas Yarsi dan Tinjaunnya Menurut Pandangan Islam
Authors: Barokah Rizki Sahrul , Purwanto Eko , Mahmud Amir
Published: November 2023

Latar Belakang: Teknologi yang berkembang pesat dengan bebagai fitur kecanggihan sebagai suatu hal yang menyebabkan proses peralihan kegiatan yang dinamis berubah statis diprediksi sebagai suatu hal yang menyebabkan tingkatan kebugaran jasmanai suatu orang mengalami penurunan. Banyak remaja yang tidak memedulikan kebugaran jasmani sehingga dapat menurunkan tingkat kebugaran jasmani. Guna melakukan peningkatan terhadap kebugaran jasmani bisa didapatkan dengan melakukan latihan olahraga yang rutin dan beraturan serta melakukan pengkonsumsian terhadap asupannya gizi yang seimbang, salah satu latihan olahraga yang cukup mudah dilakukan yaitu Jump Rope. Latihan jump rope diduga dapat mempengaruhi skor Harvard step test.Metode: Dalam penelitian yang dilakukan sebagai bentuk penelitian eksperimental yang menggunakan perancangan penelitian non-randomized pretest-posttest. Penelitian ini dilakukan di Lab Fisiologi FK Yarsi dan secara daring dari tanggal 23 November-23 Desember 2020. Dilakukan 300 kali lompatan jump rope per hari sebanyak tiga kali per minggu dan dilakukan selama 4 minggu terhadap 30 subjek laki-laki. Skor Harvard step test diukur pada saat awal dan diakhir perlakuan jump rope. Analisis data untuk membedakan hasil skor Harvard step test pre dan post menggunakan Paired T-Test dan selanjutnya untuk memastikan adanya hubungan antara jump rope dan skor harvard step test dilakukan Uji Korelasi Pearson.Hasil: Dari hasil penelitian diperoleh perbedaan nilai skor harvard step test, menjadikan sebuah proses yang dapat meningkatkan dengan begitu signifikannya terhadap rata-rata skor Harvard Step Test post perlakuan sebesar 21,34% (p=0,001). Pada hasil uji korelasi dari rata-rata durasi waktu Jump Rope selama 12 kali perlakuan dengan data skor Harvard Step Test posttest diperoleh nilai korelasi negatif sedang yang signifikan dengan nilai r = -0,393 dan p = 0,032 serta persamaan y = -1,3268x + 52,268.Kesimpulan: Terdapat perbedaaan yang signifikan pada skor Harvard step test sebelum melakukan latihan jump rope dan setelah melakukan latihan jump rope. Terdapat hubungan yang signifikan antara jump rope dengan skor Harvard step test.Keyword: Kebugaran jasmani, jump rope, Harvard step test
Hubungan Jenis Kelamin Dan Ras/Suku Dengan Kemampuan Mengecap Phenylthiocarbamide (Ptc) Pada Mahasiswa Fakultas Kedokteran Universitas YARSI Angkatan 2021
Authors: Mushorih Azriel Al , Purwaningsih Endang
Published: November 2023

Kemampuan mengecap PTC seseorang dapat berguna dan penting untuk mempelajari keragaman genetik pada populasi manusia. Sensitifitas rasa PTC penting dalam pemilihan makanan. Jenis kelamin ditentukan pada saat pembuahan. Kromosom X dari sel telur bergabung dengan kromosom seks dari sperma, baik kromosom Y menjadikan pria atau XY atau kromosom X lainnya menjadikan wanita atau XX. Suku/Ras dapat diartikan sebagai pengelompokan atau penggolongan manusia berdasarkan karakteristik fisik yang diturunkan. Tujuan penelitian adalah mengetahui frekuensi tester dan genotipnya pada mahasiswa Fakultas Kedokteran Universitas YARSI Tahun akademik 2021 dihubungkan dengan jenis kelamin dan ras/suku. Metode Penelitian adalah eksperimental dengan rancangan cross sectional. Tes PTC dilakukan menggunakan lakmus PTC. Data jenis kelamin dan ras/suku diperoleh menggunakan kuesioner. Analisis data menggunakan aplikasi SPSS Statistic versi 26 dan menggunakan analisis univariat serta analisis bivariat. Hasil penelitian menunjukan bahwa dari 202 mahasiswa didapatkan mahasiswa tester sebanyak 139 dan nontester sebanyak 63. Diantara mahasiswa tester sebagian besar berjenis kelamin perempuan. Frekuensi gen t sebesar 0,5584 dan frekuensi gen T sebesar 0,4415. Mahasiswa yang berasal dari suku jawa paling tinggi dan mahasiswa dari Bengkulu, Melayu dan Lampung paling rendah. Berdasarkan kemampuan mengecap rasa pahit (tester/nontester), jenis kelamin, dan ras/suku frekuensi tertinggi adalah suku jawa pada perempuan tester, sedangkan frekuensi terendah adalah suku Bengkulu, melayu, dan lampung pada laki-laki tester dan perempuan tester. Disimpulkan bahwa terdapat hubungan antara jenis kelamin dan ras/suku terhadap kemampuan mengecap PTC.
Relationship Between Learning Styles and Academic Performance in Yarsi University Medical Student
Authors: Christio Marylin , Mahardika Zwasta Pribadi , Istiwara Endy
Published: November 2023

Methods of medical education in Indonesia continue to experience development in line with the development of medical science and practice which has made many advances in pursuing public health. Medical education students are expected to be adaptive in achieving predetermined medical competencies. The results of the study stated that there were several factors that influenced the low achievement of students including learning strategies, learning motivation, psychological conditions, family, and health problems. Research by Jafari et al. states that there is a significant relationship between learning styles and student academic achievement.Learning styles that are consistent and in accordance with student character can improve academic achievement. The things that cause differences in learning styles include culture, ways of education, and the teaching and learning process in each institution. The data collected in this study there are 2 types of data, namely primary and secondary. Primary data collected with the VARK questionnaire instrument to assess learning styles. The secondary data collected was in the form of GPA of Yarsi University Faculty of Medicine students for the 2022/2023 academic year. The total number of respondents in this study was 240 consisting of batches of 2019, 2020, 2021, and 2022. Students of the Faculty of Medicine, Yarsi University, batches of 2019, 2020, 2021, and 2022 with a total of 240 respondents, 24 of whom had a Visual learning style (10%) , Auditory 26 (11%), Reading 118 (49%), Kinesthetic 22 (9%), and Multimodal 50 (21%). The relationship between learning styles and the Grade Point Average (GPA) has a weak correlation.
Faktor-faktor yang Mempengaruhi Anemia pada Ibu Hamil Trimester 1 di Puskesmas Kelurahan Kampung Melayu Periode Januari–Desember Tahun 2022 dan Tinjauannya Menurut Pandangan Islam
Authors: Silviani Syarah Kartika , Laksono Sonny Pamudji , Arsyad Muhammad , Sachrowadi Qomariyah
Published: November 2023

Latar Belakang: Kasus anemia pada ibu hamil cukup tinggi terutama di negara-negara berkembang. Menurut World Health Organization (WHO) 2019,  prevalensi anemia terhadap ibu hamil usia 15–49 tahun di dunia mencapai 42%. Menurut data Kementerian Kesehatan RI (2019), angka kematian janin yang disebabkan oleh anemia sebesar 28%.Metode: penelitian ini menggunakan 52 data rekam medis pasien anemia ibu hamil  di Puskesmas Kampung Melayu periode Januari –Desember  tahun 2022 dengn desain penelitian cross-sectional dengan jenis sampel yang diambil yaitu melalui teknik Purposive sampling, yaitu pengambilan sampel sesuai dengan kriteria yang dibutuhkan. Selanjutnya data akan dianalisis secara analitik melalui metode chi-square.Hasil: Berdasarkan hasil analisis chi-square, hanya status gizi yang memiliki hubungan bermakna terkait kejadian anemia pada ibu hamil trimester satu di Puskesmas Kelurahan Kampung Melayu Periode Januari—Desember tahun 2022.Kesimpulan: Dari faktor yang mempengaruhi anemia pada kehamilan seperti usia ibu haml, paritas, status gizi, tingkat pendidikan, dan status social ekonomi, hanya status gizi yang memiiki hubungan bermakna.
Wakaf Uang secara Digital dalam Perspektif Syariah pada Aplikasi Tokopedia
Authors: Raudhoh  , Rio Erismen Armen  , Iqbal Fadli Muhammad  , Roni Hidayat
Published: November 2023

Penelitian ini bertujuan untuk mengetahui definisi wakaf uang secara digital, serta tinjauan syari’ah yakni fikih muamalah dan maqashid syari’ah terhadap wakaf uang pada aplikasi Tokopedia. Hal tersebut berdasarkan adanya perbedaan yang mendasar antara pelaksanaan wakaf uang secara digital dengan praktik wakaf uang pada umumnya, sehingga memunculkan celah tidak terpenuhinya rukun dan syarat wakaf. Jenis penelitian ini menggunakan metode kualitatif dengan pendekatan bahan-bahan kepustakaan sebagai sumber data penelitian atau disebut juga library research. Data dalam penelitian ini didapatkan melalui website resmi Tokopedia dan data lainnya didapatkan melalui studi kepustakaan, seperti buku, jurnal, regulasi, ataupun penelitian sebelumnya. Hasil dari penelitian ini menjelaskan bahwa wakaf uang secara digital adalah wakaf uang yang dilakukan secara daring melalui website, platform, atau aplikasi yang tersedia fitur wakaf uang dimana sistem pembayarannya dilakukan secara tidak langsung, melalui media electronic channel, serta wakaf uang secara digital pada aplikasi Tokopedia dihukumi sah berdasarkan pada maslahah mursalah yang sejalan dengan tujuan maqashid syari’ah.
Analisis Risiko Kencing Berdiri dalam Perspektif Ilmu Kesehatan dan Hukum Islam
Authors: Afrizal Tw
Published: November 2023

Buang air kecil (BAK) dengan posisi berdiri merupakan salah satu kebiasaan yang masih banyak dilakukan oleh masyarakat dari kalangan laki-laki. Namun kebiasaan ini memungkinkan untuk menghasilkan beberapa risiko jika ditinjau dari ilmu kesehatan, seperti infeksi saluran kemih (ISK), retensi urine, dan risiko pembesaran prostat pada pria. Selain itu, kencing berdiri juga dianggap makruh oleh sebagian ulama karena dapat menyebabkan air kencing terciprat ke tubuh atau pakaian. Penelitian ini bertujuan untuk mengkaji risiko kencing berdiri dalam perspektif ilmu kesehatan dan hukum Islam. Kajian ini menggunakan metode studi literatur dengan mengumpulkan data dari berbagai sumber, seperti jurnal ilmiah, buku, dan artikel ilmiah. Hasil penelitian menunjukkan bahwa kencing berdiri dapat meningkatkan risiko infeksi saluran kemih (ISK), retensi urine, dan risiko pembesaran prostat. Selain itu, kencing berdiri juga dapat menyebabkan air kencing terciprat ke tubuh atau pakaian, sehingga dapat menyebarkan kuman dan bakteri. Berdasarkan hasil penelitian, kencing berdiri dapat menimbulkan risiko yang tidak baik bagi kesehatan dan tidak baik bagi kebersihan menurut pandangan hukum Islam. Oleh karena itu, disarankan untuk menghindari kebiasaan kencing berdiri dan menggantinya dengan kencing duduk atau jongkok apabila dalam keadaan yang memungkinkan serta tidak adanya kesulitan dalam melakukannya.
History of the crested turkey, a rare variant of the domesticated turkey (Meleagris gallopavo gallopavo)
Authors: Goddeeris Bruno M. , Goddeeris Boudewijn R.
Published: November 2023

In 1919, the famous Dutch poultry judge Cornelis van Gink (1890–1968) was aware of the existence of crested turkeys. Was this bird a natural rarity, variation or mutation? A search through historical records and published works yielded very few references to crested turkeys. From the financial accounts of the Great Condé in 1679 to pictures in books and journals of the eighteenth and nineteenth century in England and America, from a mounted specimen in Parma to a first photograph in 1938 in Newsweek, the beauty and rareness of this bird is evident. Attempts to breed crested turkeys were unsuccessful. In the nineteenth century William Bernhardt Tegetmeier (1816–1912), editor of The Field, had a major interest in these turkeys and together with Charles Darwin (1809–1882) studied and described skull deformations associated with well-known and common crested breeds of chickens. Deformation of the skull was also observed in the mounted specimen of the crested turkey preserved in Parma, Italy. Genetic analyses of crested poultry indicate that a mutation (autosomal incompletely dominant) in the crest gene is responsible for this phenotype. The mutation for crest formation with additional skull deformation might be responsible for some in ovo lethality or poor hatching which could explain the failure or difficulty in breeding this phenotype. In conclusion, all data indicate that the crested turkey is a mutation of the domestic turkey Meleagris gallopavo gallopavo and does not justify a new species or subspecies name.
Survival or Revival?: C.S. Lewis's Medievalism in The Lion, the Witch and the Wardrobe
Authors: van Dijk Conrad
Published: November 2023

C.S. Lewis's The Lion, the Witch and the Wardrobe has often been considered overly eclectic in its use of mythologies and literary sources. This essay argues that the unity of the story is not impaired by frequent allusions to previous texts but is grounded in Lewis's particular brand of medievalism, which encourages a playful renewal of medieval romance, not least by means of a rewriting of authors such as Thomas Malory. Lewis's use of allusion and pastiche help explain many of his artistic choices, from the characterization of the White Witch to the archaic language in the Hunt for the White Stag. The essay uncovers several important, unrecognized allusions and demonstrates that Lewis's use of his medieval source material is not only humorous but also purposeful and culturally relevant.
Katherine Beaumont, Countess of Atholl, and the Second Scottish War of Independence (c. 1327–c. 1336)
Authors: French Morvern , MacInnes Iain A.
Published: November 2023

Katherine Beaumont, countess of Atholl, spent several months besieged within Lochindorb Castle before being rescued by King Edward III of England in July 1336. The king’s campaign through the Highlands, Moray and Aberdeenshire has been seen by modern historians as one of his more chivalric enterprises, but very little is known about Katherine herself beyond her presence at Lochindorb. This article will begin the process of uncovering more of her own history and participation in the Second Scottish War of Independence. It will evaluate the importance of her marriage to David IV Strathbogie and her motherhood of David V within Scottish succession politics, look at her experience in Scotland as it was fought over between Bruce and Balliol, and provide a revised consideration of the siege of Lochindorb. It will also explore how and why such women’s lives and actions are difficult to discern in medieval chronicles, addressing this through the use of alternative documentary and material evidence.
Adam Ferguson, Sir John Macpherson and the French Revolution: New Evidence and Perspectives
Authors: Stewart Ian
Published: November 2023

This article examines thirty-six new letters and one essay on the French Revolution written by Adam Ferguson, and uses them to reconstruct a discussion carried on among Ferguson, Hugh Blair and Sir John Macpherson during the revolutionary 1790s. The new evidence from Ferguson casts doubt on his identification as a ‘civic humanist’, and shows that he never welcomed the French Revolution, even in its early stages. Remarkably, Ferguson also briefly supported a European union based on arms and commerce. The examination of John Macpherson—a little known but interesting figure—shows that he had a sophisticated view of commercial society and a unique theory about the dangers of systemic financial risk. Finally, the conversation contained here primarily pertains to commercial society, public credit and perpetual peace, and adds a new Scottish angle to our understanding of these major idioms in eighteenth-century political thought.
Hair-raising Adventures Loosely Organised: Early Years of The HALO Trust and Humanitarian Mine Action in Afghanistan, 1988–92
Authors: Mitchell Angus
Published: November 2023

The HALO Trust was founded in 1988 to alleviate suffering among civilians living in hazardous areas. Today, it is the largest humanitarian de-mining charity in the world. Its earliest operations were in Afghanistan. Following the Soviet withdrawal, HALO moved into Kabul where it established a clinic for casualties of war, developed mine risk education and gradually rolled out an innovative mine clearance programme. These interventions helped to transform mine clearance from being a military legacy into a humanitarian priority. Much of the early strategic foresight for HALO extended from the military experience of the former Scottish foot soldier Colonel Colin Campbell Mitchell of the Argyll and Sutherland Highlanders. Based on semi-structured interviews with key participants and access to private papers and diaries, this article provides a narrative framework for understanding the emergence of humanitarian mine clearance or ‘mine action’, as it is now termed. Through sometimes fractious dialectical relationships with various United Nations agencies and discreet dealings with Afghanistan’s communist government and regional warlords, HALO became a vital implementing partner in the work of refugee resettlement and rehabilitation assistance. Retrieving its history contributes to a clearer identification of the intersections between military expertise, development, humanitarianism and the post-Cold War world.
Partisipasi Warga Negara Digital Terhadap Proses Demokrasi Pancasila
Authors: Hidayat Obby Taufik
Published: November 2023

Studi ini menunjukkan pentingnya kewarganegaraan digital di era saat ini. Artikel ini membandingkan sembilan fitur warga negara digital (nine features of digital citizen) dengan studi kasus yang dilakukan terhadap partisipasi warga negara digital dalam mendorong pemerintahan yang lebih demokratis dan akuntabel. Pendekatan studi kasus digunakan dalam penelitian ini. Peneliti studi kasus telah berkontribusi pada pengembangan penelitian studi kasus dari berbagai disiplin ilmu. Penelitian studi kasus ini mendorong penyelidikan yang rinci dari unit analisis dalam konteksnya. Hasil studi ini menunjukkan bahwa masyarakat saat ini perlu dibina tentang sembilan elemen kewarganegaraan digital. Di era saat ini, perubahan begitu cepat sehingga dari waktu ke waktu harus ada kolaborasi dan kerjasama antar berbagai pihak untuk memastikan bahwa ketegangan antara warga negara digital dan pemerintah dapat menemukan titik temu sebagai upaya mewujudkan Demokrasi Pancasila. Dengan lebih banyak pengetahuan dan kebijaksanaan tentang pendidikan karakter, pendidikan multikultural, hak asasi manusia dan pembelajaran berbasis masalah (problem based learning) dalam Pendidikan Kewarganegaraan, guru, siswa, orang tua, dan masyarakat harus sering bertemu untuk memutuskan masalah kontroversial dan menemukan cara untuk memastikan bahwa setiap orang di masyarakat memiliki pengetahuan, keterampilan. dan nilai-nilai kewarganegaraan digital untuk tumbuh dan berkembang. Kajian ini memberikan kontribusi untuk perluasan wacana teoritis dan praktik pengembangan partisipasi warga negara digital terhadap Demokrasi Pancasila.
Clinical application of amplification-based versus amplification-free metagenomic next-generation sequencing test in infectious diseases
Authors: Wang Zhe-Ying , Li Lu-Lu , Cao Xue-Lei , Li Ping , Du Jian , Zou Ming-Jin , Wang Li-Li
Published: November 2023

Background

Recently, metagenomic next-generation sequencing (mNGS) has been used in the diagnosis of infectious diseases (IDs) as an emerging and powerful tool. However, whether the complicated methodological variation in mNGS detections makes a difference in their clinical performance is still unknown. Here we conducted a method study on the clinical application of mNGS tests in the DNA detection of IDs.

Methods

We analyzed the effect of several potential factors in the whole process of mNGS for DNA detection on microorganism identification in 98 samples of suspected ID patients by amplification-based mNGS. The amplification-based and amplification-free mNGS tests were successfully performed in 41 samples. Then we compared the clinical application of the two mNGS methods in the DNA detection of IDs.

Results

We found that a higher concentration of extracted nucleic acid was more conducive to detecting microorganisms. Other potential factors, such as read depth and proportion of human reads, might not be attributed to microorganism identification. The concordance rate of amplification-based and amplification-free mNGS results was 80.5% (33/41) in the patients with suspected IDs. Amplification-based mNGS showed approximately 16.7% higher sensitivity than amplification-free mNGS. However, 4 cases with causative pathogens only detected by amplification-based mNGS were finally proved false-positive. In addition, empirical antibiotic treatments were adjusted in 18 patients following mNGS testing with unexpected pathogens.

Conclusions

Amplification-based and amplification-free mNGS tests showed their specific advantages and disadvantages in the diagnosis of IDs. The clinical application of mNGS still needs more exploration from a methodological perspective. With advanced technology and standardized procedure, mNGS will play a promising role in the diagnosis of IDs and help guide the use of antibiotics.
Vasopressors and inotropes in cardiogenic shock patients: an analysis of the MIMIC-IV database
Authors: Sasmita Bryan Richard , Wang ChuanYing , Xie Siyuan
Published: November 2023

Introduction

Pharmacological support has become the mainstay therapy in patients with cardiogenic shock (CS). Unfortunately, the clinical benefits of such potent drugs remain unclear, therefore, the present study aims to elucidate the safety and efficacy of vasoactive agents in CS patients.

Methods

Medical Information Mart for Intensive Care (MIMIC) IV databases were used for this retrospective study. The primary outcome of this study was 30-day all-cause mortality. The subgroup analysis of was the relationship between the combined use of vasopressors and inotropes and 30-day all-cause mortality.

Results

A total of 2,216 patients diagnosed with CS were enrolled in this study. The non-survivors group was more likely to be older, presented with chronic kidney disease, have a lower systolic blood pressure, lower heart rate, and higher respiratory rate (all p < 0.05). In the multivariate Cox regression analysis, only dopamine [HR (95%CI): 1.219 (1.003–1.482)], norepinephrine [HR (95%CI): 2.528 (1.829–3.493)], and milrinone [HR (95%CI): 0.664 (0.512–0.861)] remained an independent predictor for 30-day all-cause mortality. Furthermore, a subgroup analysis was performed and found that no statistically significant difference between no vasopressor/inotrope use and 1 vasopressor/inotrope use (p = 0.107). Meanwhile, a substantial deterioration of cumulative survival was observed when a combination of 2 or more vasopressors/inotropes was used in CS patients in comparison with no vasopressor/inotrope or only 1 vasopressor/inotrope use (all p < 0.05).

Conclusions

Using vasopressors/inotropes agents was associated with a higher risk of 30-day all-cause mortality in CS patients. In addition, only milrinone was associated with a better prognosis among the available vasoactive agents.
Evaluating passive physiological data collection during Spravato treatment
Authors: Solomon Todd M. , Hajduk Matus , Majernik Martin , Jemison Jamileh , Deschamps Alexander , Scoggins Jenna , Kolar Adam , Pinheiro Miguel Amável , Dubec Peter , Skala Ondrej , Muir Owen , Tinkelman Amanda , Karlin Daniel R. , Barrow Robert
Published: November 2023

Spravato and other drugs with consciousness-altering effects show significant promise for treating various mental health disorders. However, the effects of these treatments necessitate a substantial degree of patient monitoring which can be burdensome to healthcare providers and may make these treatments less accessible for prospective patients. Continuous passive monitoring via digital devices may be useful in reducing this burden. This proof-of-concept study tested the MindMed Session Monitoring System™ (MSMS™), a continuous passive monitoring system intended for use during treatment sessions involving pharmaceutical products with consciousness-altering effects. Participants completed 129 Spravato sessions with MSMS at an outpatient psychiatry clinic specializing in Spravato treatment. Results indicated high rates of data quality and self-reported usability among participants and health care providers (HCPs). These findings demonstrate the potential for systems such as MSMS to be used in consciousness-altering treatment sessions to assist with patient monitoring.