bluuebunny/crossref_metadata_2025 huggingface dataset:
CARDIAC SURGERY PEDIATRIC DISCHARGE: THE IMPORTANCE OF THE LENGTH OF STAY
Authors: Da Valle P. , Calevro D. , Donnini D. , Baratta S. , Durante A.
Published: December 2024

Proper discharge planning is crucial for preventing postoperative complications, reducing readmissions, and enhancing the quality of life for patients and their families. In pediatric cardiac surgery, discharge marks a critical transition from hospital to home, requiring careful attention to ensure care continuity and safety. Despite its importance, nurse-led discharge programs remain underdeveloped, with inconsistent terminology and non-unique definitions in the literature. This clinical quality improvement project aims to identify factors leading to the activation of a nurse-led discharge plan for pediatric cardiac surgery patients to improve the discharge process. Methods involved retrospective audits of 300 clinical records from 2023 to mid-2024, analyzing the use of a nurse discharge letter based on the Cantarelli model, employed in the pediatric cardiac surgery unit since 2008. Among 300 patients, 235 did not receive a discharge nursing letter, with language barriers accounting for 99 cases. Sixty-four patients received the nurse discharge letters, which include suggestions about the surgical area hygiene (n=60), wound care (n=57), and movement (n=56). A significant association (p=0.040) was found between length of stay (LOS) and the likelihood of receiving a nurse discharge letter. Patients with LOS > 16 days were less likely to receive a letter, while those with LOS < 11.5 days were more likely to receive one. These findings suggest that longer hospital stays may provide sufficient time for education on care management, reducing the need for formal discharge instructions. Despite limitations, understanding patient needs is essential for developing effective future care plans.
BIOLOGICAL PROSTHESES IN PATIENTS YOUNGER THAN 65 YEARS OLD: A PROPENSITY-SCORE MATCHING ANALYSIS BETWEEN THE TWO MOST IMPLANTED BOVINE PERICARDIAL VALVES.
Authors: Perrone F. , Francica A. , Onorati F. , Denora M. T. , Maffei I. , Luciani G. B.
Published: December 2024

Background and Aim:

The latest ESC/EACTS guidelines recommend the use of biological prostheses in patients over 65 years old for aortic valve replacement. However, in recent years, there has been an increasing use of bioprosthetic valves in younger patients as well. This study aimed to compare the six-year results in ≤65 years old patients receiving the last two generation of bovine pericardial valves (Perimount Magna Ease and Inspiris Resilia) in the aortic position.

Methods:

From 2017 to 2023, clinical and echocardiographic data of patients receiving PME and IR prosthesis for isolated or combined AVR were prospectively collected at our Institution. Propensity score (PS) matching was performed to compare the groups at 6-years follow-up.

Results:

A total of 2053 patients were included: 1602 PME and 451 IR. After propensity score matching, 224 pairs of patients with similar risk profiles were compared. IR valve showed good six–year freedom from explant, endocarditis and stroke comparable to PME valve. However, causes of cardiovascular mortality should be better assessed in PME patients (Log-rank test p=0.028). Infective Endocarditis was the main cause of valve explant in both cohorts (46.7% in PME vs 53.3% in IR). After an initial lower transproshtetic mean gradients and peak velocity in IR valves, PME and IR valve showed comparable hemodynamic from 1 to 6 years of follow- up.

Conclusions:

In patients under 65 years of age, the new generation of IR prostheses showed good clinical and echocardiographic results similar to those of PME prostheses; however, with lower cardiovascular mortality at 6 years.
SURGICAL MANAGEMENT OF ANOMALOUS AORTIC ORIGIN OF THE CORONARY ARTERY (AAOCA): A 20 YEARS SINGLE CENTER EXPERIENCE
Authors: Messina C. , Corrado C. , Rosato A. , Anglese S. , Reali M. , Varrica A. , Frigiola A. , Giamberti A. , Lo Rito M.
Published: December 2024

Background and Aim:

Surgical repair of anomalous aortic origin of coronary artery (AAOCA) needs to be patient’s tailored to reduce early and late complications. We aim to assess the results of 21-years AAOCA surgical repair in a dedicated program.

Methods:

All consecutive AAOCA patients underwent surgical repair (01/2013- 09/2024). We collected anatomical operative and post-operative data, focusing on early complications and late outcomes.

Results:

From a cohort of 237 AAOCA subjects referred, 69 (29%) underwent surgical repair at a median age of 39,7 years (range: 5-71 years). The surgical techniques were unroofing of the intramural segment (n=53), osteoplasty (n=5), anatomical repair (n=4) CABG (n=3), transconal repair (n=1), external debridging of subpulmonary course (n=3). No early or late mortality was depicted. Early complications included unplanned CABG (n=1) a right coronary laceration requiring patch repair (n=1) and acute pericarditis requiring pericardiectomy (n=1). All patients were discharged in good clinical conditions, with no evidence of aortic valve regurgitation. After a mean follow-up of 4.5±3.98 years, the occurrence of late overall complications was rare, with only 1 case of RCA stenosis after unroofing treated with stenting; meanwhile we observed post-surgical pericarditis (n=3) treated medically 1 case of distal RCA spontaneous dissection.

Conclusions:

When tailored to the specific patient anatomy, surgical treatment of AAOCA may significantly reduce early and late complications. Surgery is safe when performed in large-volume centers, although the very long-term fate of a repaired coronary segment in young adults in terms of stenosis recurrence is still unknown.
LONG TERM OUTCOME OF TETRALOGY OF FALLOT AND COMPLETE ATRIOVENTRICULAR SEPTAL DEFECT REPAIR: SINGLE CENTRE EXPERIENCE
Authors: Perri G. , Brancaccio G. , Filippelli S. , Trezzi M. , Cetrano E. , Iacobelli R. , D’Inzeo V. , Galletti L.
Published: December 2024

Background:

We report our experience following surgical repair of Complete Atrioventricular Septal Defect (cAVSD) with Tetralogy of Fallot (TOF) over a 30 years period, focusing particularly in approach used for right ventricular outflow tract reconstruction (RVOTR).

Methods:

Between 1992 and 2023, 47 children with primary diagnosis of cAVSD/TOF were treated in our Institution; 39 had Down’s syndrome (81%). All except 6 had diagnosis of Rastelli’s type C. Median age and weight at surgery were 25 mos (range 4 – 224) and 12.5 Kg (range 3.5 – 83). 22 patients received initial palliation while 25 underwent direct repair. cAVSD was treated in all by double-patch technique while RVOT obstruction was relieved by transannular patch (TAP) in 21 cases (43.7%), infundibular patch in 12 (25%), and valve conduit in 11 (31,3%). Primary outcome were survival and freedom from reintervention

Results:

No hospital deaths occurred. Overall survival was 93.75% and 87,5% at 5 and 10 years respectively. Six patients died during follow-up, 3 after palliation before complete repair. Amongst 44 patients underwent repair, 24 (54%) need reintervention: 10 previously treated with conduit (91.6%), 6 (50%) with infundibular patch and 8 (35%) with TAP. Most common reintervention was conduit replacement (41,6%), followed by mitral valve surgery (20.8%).

Conclusions:

TOF with cAVSD can be repaired at low risk with favourable long-term outcome. Primary repair, when feasible, should be preferred in order to avoid inter- stage mortality. Transannular patch is a valid alternative for RVOTR because improve long-term outcome and prevents multiple conduit replacement
THE BOLOGNA’ SCORE: A NOVEL RISK STRATIFICATION TOOL FOR ADULT WITH CONGENITAL HEART DISEASE UNDERGOING HEART TRANSPLANTATION
Authors: Orioli V. , Careddu L. , Mangerini V. F. , Berardi M. , Petridis F. D. , Agulli M. , Ragni L. , Assenza G. E. , Rucci P. , Gargiulo G. D. , Angeli E.
Published: December 2024

Background:

Grown-up congenital heart disease patients (GUCHs) represent an expanding population characterized by higher early post heart transplant mortality compared with the population without congenital heart disease. Aim of our study was to identify potential preoperative risk factors and to develop a risk-score that could complement the pre-transplant assessment of GUCHs.

Methods:

From 2009 to 2024, 33 GUCHs underwent heart transplantation. Spearman’s correlation coefficient or Kendall’s tau were used to examine bivariate relationship between pre-transplant variables and mortality. Variables were explored using a correlation matrix: positive or negative correlations greater than 0.30 in absolute value were highlighted. ROC analysis was performed to evaluate predictive ability of the variables and score. Optimal cut-offs were identified by Youden’s J index. Moreover, ROC analysis was used to compare our score with the score proposed by Seese et al.

Results:

Seven predictors resulted associated with mortality: sodiemia (p=0.024), haemoglobin (p=0.013), haematocrit (p=0.007), FEV1 (p=0.068), systolic pulmonary artery pressure (PAP, p=0.037), diastolic-PAP (p=0.011) and mean-PAP (p=0.013). Overall survival in patients with Bologna’ score greater than 3 was 75%, 63% and 63%, while in patients with Bologna’ score lower than 3 was 88%, 83% and 83% at 1,5 and 10 years respectively(log-rank=0.037). ROC analysis comparing the two scores revealed a better accuracy of the Bologna score (AUC=0.730) than Seese’s score (AUC=0.488).

Conclusions:

Mortality in GUCHs is not only influenced by cardiac pathology but by the patient’s overall compensation picture. The developed population-specific risk-score showed to be predictive for mortality and could be used in the pre-transplant evaluation of GUCHs.
A MODIFIED END-TO-SIDE APPROACH FOR AORTIC ARCH RECONSTRUCTION IN NEONATES YIELDS OUTSTANDING OUTCOMES
Authors: Hafdhullah M. , Varrica A. , Abrami G. , Reali M. , Lo Rito M. , Torchio F. , Giamberti A. , Parolari A. , Tarus A.
Published: December 2024

Background and Aim:

This study focuses on evaluating the outcomes of a modified end-to-side aortic arch reconstruction for treating hypoplastic aortic arch with or without coarctation of the aorta and interrupted aortic arch via sternotomy in infants.

Methods:

This study retrospectively reviewed 60 infants who underwent modified end- to-side reconstruction at our institution between January 2020 and January 2024. The study evaluated mortality, morbidity and reinterventions.

Results:

A total of 60 patients (32 males) were included in this study. Mean age at surgery was 49 days. Patients were divided into: group A, arch anomalies with or without ASD and/or VSD; group B (55%) arch anomalies associated with TGA, single ventricle physiology, DORV, CAVC, MV stenosis and subaortic stenosis. Three patients (6.2%) died during postoperative period, all from group B. Incidence of postoperative complications was 30%, wound dehiscence (9%), acute neurological lesions (8%) and vocal cord paralysis (6%). Bronchial compression was not observed in any patient. Three patients required early reoperations due to residual valvular dysfunction. Mean CPB time was 152 minutes, mean aortic cross-clamp time was78 minutes and mean antegrade cerebral perfusion time was 40 minutes.

Conclusion:

Modified end-to-side technique in neonates is safe and effective with favorable outcomes. This approach reduces the incidence of some common complications by minimizing the tension on the anastomosis, reducing ovalization of the aortic lumen, thereby reducing future reobstruction; it prevents compression on the left bronchus and protects the left recurrent laryngeal nerve from inadvertent injuries. Selective cerebral perfusion is a key factor in minimizing acute brain injuries.
AORTIC STENOSIS IN INFANTS: SUCCESS AND CHALLENGES OF THE ROSS-KONNO PROCEDURE
Authors: Hafdhullah M. , Varrica A. , Abrami G. , Reali M. , Lo Rito M. , Torchio F. , Giamberti A. , Tarus A.
Published: December 2024

Background and Aim:

Aortic stenosis in infants demands a safe and durable solution. Ross-Konno procedure offers a promising alternative. The aim of this research was to describe the results following Ross-Konno procedure conducted on infants.

Methods:

This study retrospectively analyzed outcomes of Ross-Konno in 14 infants younger than 1year, between December 2009 and July 2023. Patients were followed up to a median of 2.07 years (IQR: 0.8- 4.1). Primary outcomes measured included survival rates, morbidity, reintervention, mid-term functional and echocardiographic assessments.

Results:

Median age at operation was 98 days (IQR: 60-145), median weight was 5 kg (IQR: 4.3-6). Eleven patients (78%) had undergone prior procedures, balloon valvuloplasty in (64%). Median CPB time was 189 minutes (IQR: 180-198), median aortic cross-clamp time was 142 minutes (IQR: 129-157). Six patients required concomitant mitral valve surgery or aortic arch reconstruction. There was one early death, a neonate weighing 2.8 kg; one late death at 4 years of age. Freedom from reoperation on autograft was 100% at 1 year, 93% at 5 years. One aortic root replacement was performed 4 years after Ross-Konno in infancy. Three pulmonary conduits required reintervention (21%). Neoaortic Z-scores remained consistent from 4 weeks after procedure to the most recent follow-up. Two patients needed permanent pacemaker due to complete heart block.

Conclusions:

Ross-Konno procedure serves as viable primary solution for aortic stenosis in infants, offering durable and high-quality outcomes. With precise surgical technique, it effectively establishes robust LVOT and reduces likelihood of future reinterventions. Despite potential for significant complications, this procedure provides excellent survival rates, stable neoaortic function, and preserved ventricular performance.
Research on the Generative LoRa Model for Enhancing the Attractiveness of Virtual Human Facial Features
Authors: Li Qi , Zhang Jianyi , Liu Dawei
Published: December 2024

With the advent of generative AI models such as ChatGPT, a plethora of virtual humans have surfaced as spokespersons for live broadcasts. Capturing the attention of the younger demographic has become a critical aspect of the attention economy, necessitating the development of models for attractive virtual human facial features. This study utilizes representative virtual human samples for facial feature combinations and trains the LoRa model using attention preference data gathered from eye movement experiments. The facial features of the characters generated by the trained model align with the most attention-grabbing sample images from the experimental results, demonstrating a promising attempt to enhance the attractiveness of virtual humans.
3D Internet of Things Virtual Art Animation Lab Design
Authors: Chen Jianjun
Published: December 2024

Virtual laboratory teaching based on information technology provides a viable solution to the current problems of insufficient experimental equipment and places, as well as the inability to meet the personalized needs of students’ experiments. This paper uses the VR-Platform tool to create a virtual reality environment, and the Qt software toolset is chosen as the platform for the virtual laboratory art animation system. The interaction method’s overall design framework is used to design the human skeleton for character bone animation, resulting in a highly anthropomorphic character animation model. Study joint motion and skeleton kinematics to design interactive actions and control animation speed. Utilize matrix and quaternion mixing techniques to carry out spatial transformation and complete the interaction between art animation and virtual scenes. Utilizing the Internet of Things technology, design the remote server, network data transmission, and mobile intelligent terminal of the virtual art animation laboratory. Finally, the virtual art animation laboratory system’s operation module is developed, tested, and analyzed in terms of system performance and impact on experience. The test results show that the system’s total reading time is about 2.65% of the total rendering time, which is good real-time performance. Meanwhile, the system’s scores in the six evaluation dimensions are all greater than 4.0, indicating a good practical teaching effect. Therefore, it is of enormous significance to construct a virtual art animation laboratory to improve the practical skills of current art animation students.
Knowledge and attitude towards strabismus in Riyadh, Saudi Arabia
Authors: Almuqbil Abdulaziz , AlHajri Raneem , Alkhalifah Khalid , Salamah Rawan , Alghamdi Sarah , Daghreeri Abdulrahman , Alzahrani Adnan , Alyousif Ramy , Almazrou Abdulrhman
Published: December 2024

Objective: This study aimed to assess the knowledge and attitude of adults in the Riyadh region regarding strabismus, as well as the potential factors influencing these perceptions.
Methods: A cross-sectional web-based questionnaire study was conducted in Riyadh city, targeting participants of varying ages, genders, educational backgrounds, occupations, and marital statuses. The study utilized an online self-administered questionnaire in the Arabic language to collect data. Participants were randomly selected using a sample size of 566.
Results: The study revealed a majority of participants falling within the 18-30 years age range (42.9%) and a higher proportion of females (58.1%). Educational backgrounds varied, with 62.0% holding bachelor's degrees. Knowledge about strabismus symptoms, causes, and treatment options showed variations among participants, with 68.0% correctly identifying strabismus as a visual defect leading to eye misalignment. While a majority recognized double vision (58.2%) as a symptom, 21.6% incorrectly perceived strabismus as limited to inward eye turning. Family history (54.2%) was commonly recognized as a cause. For treatment, 59.0% identified glasses or contact lenses for children, while 68.5% recognized surgical intervention for adults. Complications such as affecting the aesthetic appearance (58.1%) and self-confidence (55.3%) were commonly acknowledged. Attitudes varied, with 34.5% willing to associate with individuals with strabismus. Experiences of bullying related to strabismus were reported by 28.8%.
Conclusion: While a substantial proportion exhibited accurate understanding, knowledge gaps existed, particularly regarding the definition, causes, and non-surgical treatment options. The findings emphasize the importance of public health initiatives to raise awareness and promote social inclusivity.
Barriers and Solutions in Integrating Technology in Disaster Management: Insights from Saudi Arabia's Emergency Operations Centers
Authors: Abualenain Jameel
Published: December 2024

Background: Integrating technology into disaster response, particularly in health crisis management, enhances communication, resource management, and patient care. However, critical barriers such as system interoperability, network reliability, and insufficient specialized training hinder its effective adoption.
Aim and Objective: This study explores the challenges faced by emergency operations center (EOC) leaders in Saudi Arabia in adopting technology for disaster medicine and identifies practical solutions to improve disaster preparedness and response.
Methods: A structured survey was administered to 110 EOC leaders, achieving a response rate of 78.2%. The survey incorporated validated tools to assess technology usage, training adequacy, and implementation challenges. Quantitative data were analyzed using descriptive statistics, while qualitative responses were explored through thematic analysis.
Results: Among the 86 respondents, 91.9% reported using telemedicine and digital tools in disaster scenarios. However, 58% found training inadequate, 44% cited staff resistance to new technologies, and 42% highlighted connectivity issues as a significant challenge. Data security concerns were noted by 11%, particularly among older respondents. Correlation analysis revealed that leaders with greater experience perceived technology as more impactful, especially for communication and patient care. Thematic analysis also highlighted the importance of involving staff in decision-making to reduce resistance.
Conclusion: Addressing training gaps, building resilient communication networks, and fostering adaptability among staff are critical to advancing technology integration in disaster response. These findings provide actionable insights for Saudi EOCs and offer a roadmap for enhancing global disaster medicine frameworks.
Al-Nahda dan Munculnya Aliran-Aliran pada Sastra Arab Modern
Authors: Hasan Insanul , Ferdinal Ferdinal
Published: December 2024

Artikel ini bertujuan untuk menguak muculnya berbagai aliran sastra Arab pada masa Al-Nahda berikut fenomena yang melatarbelakanginya. Penelitian ini merupakan penelitian kajian pustika yang menggunakan metode deskriptif analisis. Hasil penelitian ini menunjukkan bahwa kebangkitan sastra Arab dari keterpurukan merupakan awal periode modern. Titik balik itu muncul ketika ekspansi Napoleon Bonaperte sampai di Mesir pada tahun 1798, memberikan kesempatan Mesir bersentuhan dengan kebudayaan Barat. Dari pertemuan ini salah satunya berdampak pada perkembangan sastra Arab. Perkembangan aliran Sastra Arab tidak terlepas dari fenomena ini tentu dengan karakteristik dan ciri-ciri yang membedaknnya. Sastra Arab mengalami tranformasi yang membedakannya dari periode sebelumnya. Pada fase Modern, berbagai aliran muncul dalam sastra Arab secara silih berganti. Kemunculan aliran ini disebabkan oleh adanya kritikan terhadap model sastra yang muncul sebelumnya ataupun untuk menyempurnakan aliran yang muncul pada masa terdahulu. Dalam artikel ini akan menfokuskan kepada tiga aliran, yaitu: Neo-Klasik, romantisme, dan realisme.
Prevalência e fatores associados à hipertensão arterial sistêmica em adultos cadastrados na Estratégia Saúde da Família de um município do Nordeste do Brasil
Authors: Tapioca Thatiane Silva Costa , Goís Joselice Almeida , Nascimento Mônica de Andrade , Rodrigues Eder Pereira , Silva Carlos Alberto Lima da , Sobrinho Carlito Lopes Nascimento
Published: December 2024

Objetivo: Estimar a prevalência e investigar fatores associados a hipertensão arterial sistêmica em uma amostra aleatória de adultos, com idade igual ou superior a 18 anos, cadastrados na Estratégia Saúde da Família em um município do estado da Bahia. Métodos: Trata-se de um estudo com delineamento transversal conduzido com uma amostra aleatória de 337 indivíduos adultos. Foram considerados hipertensos os indivíduos que apresentaram no momento da aferição, pressão arterial sistólica ≥ 140 mmHg e/ou pressão arterial diastólica ≥ 90 mmHg. Os fatores investigados compreenderam características sociodemográficas, hábitos de vida e características antropométricas. Utilizou-se a análise bivariada para investigar a relação entre as variáveis independentes e a hipertensão. E a regressão logística com método hierarquizado, para controlar os fatores de confusão. Resultados: A prevalência de HAS foi de 49,6%. No modelo final, observou-se que o sexo masculino (p = 0,000), baixa escolaridade (p = 0,019), circunferência da cintura aumentada (p = 0,048) e razão cintura-estatura aumentada (p = 0,028) foram fatores de risco independentes, associados à hipertensão. Conclusão: Observou-se elevada prevalência de hipertensão arterial. Os principais fatores associados identificados no estudo são passiveis de alteração. Assim, estas evidências, podem contribuir para formulação de ações que estimulem mudanças de estilo de vida na população.
Avaliação de equilíbrio e força de membros inferiores em jogadores de futebol com paralisia cerebral
Authors: Oliveira Marcia Camila Ferreira de , Santos Kezia Caroline Ferreira dos , Brito Maria Clara Costa , Silva Yuri Gomes da
Published: December 2024

Objetivo: Este estudo visou avaliar o equilíbrio e a força dos membros inferiores de atletas praticantes de futebol que tem paralisia cerebral (PC) e, além disso, visa distinguir o desempenho físico entre diferentes graus de comprometimento. Métodos: Foram coletados dados de 13 atletas do sexo masculino, com idades entre 18 e 27 anos, divididos em grupos de acordo com o grau de comprometimento: Comprometimento Leve (FT3), Moderado (FT2) e Severo (FT1). Os grupos foram submetidos a testes físicos de salto horizontal, salto vertical e à Escala de Equilíbrio de Berg. Resultados: Os atletas FT3 apresentaram desempenho superior nos testes de salto vertical (média de 47,0 cm) e salto horizontal (média de 190 cm), em comparação aos atletas FT2 e FT1. Não houve diferenças significativas na Escala de Equilíbrio de Berg entre as categorias funcionais. Esses achados sugerem que a força explosiva dos membros inferiores é maior em atletas com menor grau de comprometimento motor. Conclusão: Esse estudo demonstra que os testes de salto são ferramentas eficazes para avaliar a força dos membros inferiores em atletas de futebol PC, destacando diferenças significativas entre as categorias funcionais. Estudos futuros devem incluir amostras maiores e outras variáveis que impactem o desempenho funcional.
O Impacto da atenção primária à saúde no cuidado do paciente diabético em Insulinoterapia
Authors: Rego João Pedro Costa do , Moraes Guilherme Augusto Silva de , Luz Edilana Soares , Martins Camila Gusmão Trajano , Martins Jamile Gusmão Trajano , Silva Daniel Patrick Alves da , Abreu Neto Antonio de Almeida , Oliveira Pedro Henrique Sales de , Saraiva Natássia Gabrielle de França , Santos Karina Rodrigues dos
Published: December 2024

Objetivo: Identificar o conhecimento produzido acerca do papel da atenção primária à saúde (APS) no cuidado do paciente em insulinoterapia entre 2013 e 2023. Métodos: Esta revisão bibliográfica incorporou abordagens qualitativas e quantitativas. A estratégia de busca envolveu quatro bases de dados: PubMed/Medline, SCOPUS, LILACS e Scielo, utilizando termos-chave específicos. Foram aplicados critérios de inclusão e exclusão para selecionar artigos completos publicados entre 2013 e 2023, em português, inglês ou espanhol. Os artigos foram avaliados por meio de títulos, resumos e leitura completa. Resultados: Foram encontradas 359 referências, das quais 26 foram selecionadas. Os resultados revelam que a prescrição e adesão à insulinoterapia na APS são influenciadas pela relação médico-paciente e inseguranças dos pacientes. Intervenções eficazes na APS podem potencialmente melhorar a adesão à insulina. Considerações finais: O manejo da diabetes na APS é crucial para reduzir complicações e mortalidade. A terapia insulínica enfrenta desafios como resistência dos pacientes e falta de especialistas. Uma abordagem multidisciplinar é fundamental para aprimorar a educação em saúde e a adesão ao tratamento.
Need to reconsider national quality standards for red cell components: Evidence from a retrospective observational analysis
Authors: Das Indranil , Khetan Dheeraj , Verma Anupam , Priyadarshi Atul , Chaudhary Rajendra K.
Published: December 2024

Background & objectives

Red cell concentrates (RCCs) must comply with applicable quality control (QC) standards to achieve the desired therapeutic effect in the recipient. In this study, we assessed the effect of change in the component preparation process on the quality of RCCs and their compliance with different QC standards.

Methods

A retrospective analysis of data for QC testing of RCCs over a period of 10 years, (from 2009 to 2019), was undertaken. QC testing parameters [volume, haematocrit (Hct), haemoglobin (Hb) content, white blood cell (WBC) content and percentage (%) haemolysis] were used to assess compliance with three national and three international QC standards. Linear regression analysis was done to assess the influence of donor variables.

Results

Data from 5,218 RCC units was included in the analysis. A majority (>50%) of RCCs prepared did not meet the three national QC standards either for volume or for Hct. The criteria for volume, Hct and Hb content, as defined in different international standards, were fulfilled by a majority (>75%) of RCCs evaluated. RCCs prepared by the buffy coat method had overall better compliance with QC standards compared to the platelet-rich plasma (PRP) method. The method of component preparation was found to influence Hb content, WBC content and percentage haemolysis. Male gender was associated with better Hb content.

Interpretation & conclusions

RCC prepared at our centre was found to have better compliance with international QC criteria compared to national standards. There is a need to reconsider the current national QC criteria for red cells with due consideration to the volume of whole blood collected and the method used for RCC preparation.
Impact of platelet transfusion on outcome, clot dynamics, and platelet function in thrombocytopenic trauma patients
Authors: Mukhopadhyay Tapasyapreeti , Subramanian Arulselvi , Albert Venencia , Kumar Anand , Pandey Shivam , Pati Haraprasad
Published: December 2024

Objectives:

Of all trauma patients, 25% require a blood transfusion, of which 2–3% receive a massive transfusion. In severely injured bleeding trauma patients, early platelet administration has been shown to improve hemostasis and decrease mortality. The aim was to compare the changes after platelet transfusion on prothrombin time (PT) and activated partial thromboplastin time (aPTT), platelet function, and clot dynamics in thrombocytopenic trauma patients and to identify independent risk factors for in-hospital mortality.

Materials and Methods:

Thrombocytopenic trauma patients who received platelets either with/without receipt of other blood components over two years were included in this prospective study. The pre-and post-transfusion platelet count, coagulation profile, clot dynamic analysis assessed by thromboelastography, and platelet function analysis assessed by flow cytometry were compared. The primary outcome was in-hospital mortality.

Statistical analysis:

Data is summarized as mean±S.D or median (minima-maxima) for continuous variables and for categorical variables data is presented as frequency and percentages.

Results:

Of the 45 thrombocytopenic trauma patients included in the study, 23 (51.1%) were refractory to platelet transfusion and 14 (31.1%) died. Significant differences were seen in alpha angle (P = 0.02) and maximum amplitude (P = 0.01), number of patients with coagulopathy (P = 0.007), percentage of patients with increased k-time (P = 0.03), and decreased alpha angle (P = 0.001) pre- and post-transfusion. The non-survivors had significantly lower post-transfusion PC (P < 0.001), increased pre- and post-transfusion PT (P = 0.007 and P = 0.01, respectively), and increased pre-and post-transfusion aPTT (P = 0.009 and P = 0.002, respectively). No significant differences were observed based on the thrombolelastography and platelet function parameters between survivors and non-survivors. Pre-transfusion aPTT and coagulopathy post-transfusion were independently associated with mortality (odds ratio [OR]: 9.4; 95% confidence interval [CI]: 1.6–54.3; P = 0.01 and OR: 12.6; 95% CI: 1.55–102.9; P = 0.01, respectively).

Conclusions:

Prothrombin time coagulopathy status, clot kinetics, and clot strength improved after platelet transfusion. Pre-transfusion aPTT and coagulopathy post-transfusion are independent risk factors for death in thrombocytopenic trauma patients. The clinical significance of platelet function analysis and clot dynamics in thrombocytopenic trauma patients undergoing transfusion therapy is yet to be ascertained.
МАТРИЦА РИСКОВ, ВЛИЯЮЩИХ НА ГОРОД ВОЛГОГРАД ПРИ ПОДГОТОВКЕ К ПРОВЕДЕНИЮ ЧЕМПИОНАТА МИРА ПО ФУТБОЛУ 2018 ГОДА
Authors: Степанян В.М. , Беликова Е.В.
Published: December 2024

В статье выделены и рассмотрены основные виды рисков, которые могут возникнуть при подготовке и проведению чемпионата мира по футболу в Волгограде. Была разработана матрица рисков, где определена максимальная возможная степень потенциального ущерба, который могут нанести идентифицированные виды рисков, распределенных по отдельным городам — организаторам проведения чемпионата мира по футболу 2018 года. Проанализирована матрица рисков, влияющих на город и подготовку к чемпионату мира по футболу, даны рекомендации по преодолению рисков, которые влияют на подготовку к чемпионату мира по футболу в Волгограде.

The article identifies and describes the main types of risks that may arise during preparation and holding of the football world Cup in Volgograd. The risk matrix is developed, which identifies the maximum possible degree of potential harm of the identified types of risks distributed by the cities of the world football championship 2018. The matrix of risks affecting the city and preparation for the world Cup is analyzed; the recommendations for overcoming the risks that affect the preparation for the football world Cup in Volgograd are provided.
О ПОЛЯРНОМ ВОЗДЕЙСТВИИ КРЕДИТА НА ЭКОНОМИКУ
Authors: Трифонов Д.А.
Published: December 2024

Будучи частью экономической системы, кредит отражает проблемы общественного развития, которые невозможно рассматривать изолированно от состояния экономики в целом. Но может ли кредит стать причиной экономических кризисов? В принципе кредит — благо или зло? И каково его влияние на каждого и экономику в целом? В исследовании показано, что кредит способен оказывать существенное влияние на экономический процесс. Выделены возможности российской экономики и определены угрозы, противостоящие данным возможностям. Приведены аргументы, доказывающие функциональную ограниченность существующей в стране банковской кредитной системы. Проанализированы позитивные и негативные стороны потребительского кредитования. Предложены меры, способные минимизировать кредитную зависимость россиян.

Being a part of the economic system, the credit reflects the problems of social development, which cannot be considered isolated from the state of the economy as a whole. But can the credit be the cause of the economic crises? Are loans — good or evil as a matter of fact? And what is their impact on everyone and the economy as a whole? It is shown that the credit due to its objective characteristics can have a significant impact on the economic process. The possibilities of the Russian economy in modern conditions are marked, and the threats that confront these possibilities are identified. The arguments which prove the functional limits of the existing country’s banking credit system are given. Positive and negative aspects of consumer lending are analyzed. Measures to minimize the inherent destructive credit quality and reduce loan dependence are proposed.
ХУДОЖЕСТВЕННЫЙ ТЕКСТ КАК СРЕДСТВО ОБУЧЕНИЯ ИНОСТРАНЦЕВ РУССКОМУ ЯЗЫКУ
Authors: Моисеева А.А.
Published: December 2024

В статье говорится о проблемах усвоения русских художественных текстов в обучении русскому языку как иностранному. Определяются преимущества изучения языка через чтение художественных текстов, а также приемы и условия, при которых художественный текст помогает иностранцам обучаться и совершенствовать знание русского языка. Автором были исследованы такие проблемы, как межкультурная коммуникация, трудности, возникающие в процессе чтения, а также проблема отбора художественных текстов для уроков. Полученные в ходе проведения исследования рекомендации и теоретические представления будут особенно полезны для начинающих преподавателей русского языка как иностранного.

This article covers the information about problems of assimilation of the Russian fictional texts in training in Russian as the foreign language. The author defines advantages of studying the language through reading fictional texts and also receptions and conditions under which the fictional text helps foreigners to study and improve knowledge of Russian. The author investigated such problems as cross-cultural communication, the difficulties arising in the course of reading and also the problem of selection of art texts for lessons. The recommendations and theoretical representations received during researches will be especially useful to the beginning teachers of Russian as the foreign language.
СТАНОВЛЕНИЕ ИНФОРМАЦИОННОГО ПОСРЕДНИЧЕСТВА В СОВРЕМЕННЫХ УСЛОВИЯХ РОССИЙСКОЙ ФЕДЕРАЦИИ И ЕГО ПРАВОВЫЕ ОСНОВЫ
Authors: Валкирный С.С.
Published: December 2024

В статье рассмотрены особенности становления информационного посредничества в России. В ходе исследования обозначаются проблемные положения законодательства об авторском праве. Рассмотрены вопросы правового регулирования деятельности информационного посредника. Исследованы определения понятия «информационный посредник». Обозначено юридическое содержание правоотношения, образующие права и обязанности его участников. Выявлена проблема регламентации информационных посредников в сети Интернет по отношению к объективным потребностям. Устанавливается проблема по существу отмеченных трудностей при применении норм права, ввиду того что они применяются с учетом определенных ограничений. В результате анализа общей картины проведенного исследования были подведены итоги сложившейся ситуации по исследуемой проблеме.

The peculiarities of formation of the information intermediation in Russia are examined in the article. The study identifies the problematic provisions of copyright law. The issues of legal regulation of the information intermediary activity are considered. The definitions of the term «information intermediary» are investigated. The legal content of the legal relationship forming the rights and duties of its participants is indicated. The problem of regulation of information intermediaries in the Internet in relation to objective needs has been revealed. The problem of essentially noted difficulties in the application of legal norms is established, in view of the fact that they are applied in view of certain limitations. As a result of the analysis of the general picture of the conducted research, the results of the situation on the investigated problem were summed up.
К ВОПРОСУ О СООТНОШЕНИИ ПОНЯТИЙ ГРАЖДАНСКО-ПРАВОВОЙ ОТВЕТСТВЕННОСТИ И НАКАЗАНИЯ
Authors: Цветков С.Б.
Published: December 2024

Представлен авторский подход к предпринятым в литературе попыткам охарактеризовать правовую природу ответственности за нарушение обязательств посредством умаления ее восстановительной функции и утверждения наличия карательной функции. Формулируются выводы: основной функцией названного вида юридической ответственности является восстановительная; категории «ответственность за нарушение обязательств» и «наказание» в цивилистическом аспекте, как правило, нетождественны; гражданско-правовую ответственность можно рассматривать в качестве наказания, только когда отрицательные последствия для должника превышают те выгоды, которые он получил вследствие нарушения обязательства; ее карательную функцию точнее определить как предупредительно-штрафную.

The article presents the author’s approach to the attempts to characterize the legal nature of liability for breach of obligations by belittling its regenerative functions and statement of the punitive function. The following conclusions have been drawn: the main function of the named type of legal responsibility is restorative; the categories of «liability for breach of obligations» and «punishment» in the civil law aspect, as a rule, are not identical; civil liability can be regarded as a punishment only when the negative consequences for the debtor exceed the benefits that he received as a result of the breach; punitive function more accurately defined as a warning-penalty.
ПРИНЦИПЫ ФОРМИРОВАНИЯ ИНТЕГРИРОВАННОЙ УПРАВЛЕНЧЕСКОЙ ОТЧЕТНОСТИ КОМПАНИИ
Authors: Гришина Е.А. , Мельникова В.М.
Published: December 2024

В последнее время многие компании составляют значительное количество различных отчетов, что приводит не только к росту предоставляемой информации, но и зачастую к ее разрозненности. В связи с этим была предложена идея создания интегрированной отчетности. Данный вид отчетности позволит, с одной стороны, снизить объем предоставляемой информации, а с другой — отразить взаимосвязь финансовых и нефинансовых результатов деятельности компании со стратегическими целями. В данной статье рассматриваются вопросы создания интегрированной управленческой отчетности с учетом специфики электросетевой компании. 

Recently, many companies make up a significant number of different reports, which leads not only to the growth of information provided, but often to its fragmentation. In this regard, the idea of creating integrated reporting was proposed. This type of reporting will allow, on the one hand, reducing the amount of information provided, and on the other hand, reflecting the relationship between financial and non-financial performance of the company with strategic objectives. This article discusses development of the integrated management reporting, taking into account the specifics of the electric grid company.
ВИДЫ ПРАВООТНОШЕНИЙ, ВОЗНИКАЮЩИХ В СВЯЗИ С ПРИМЕНЕНИЕМ ВСПОМОГАТЕЛЬНЫХ РЕПРОДУКТИВНЫХ ТЕХНОЛОГИЙ
Authors: Лавор Ю.М.
Published: December 2024

В статье отношения, возникающие при применении вспомогательных репродуктивных технологий, рассматриваются как единый сложный комплекс общественных отношений, проводятся классификации этих отношений как по известным отечественной доктрине основаниям, так и по специальным, применимым только к данным отношениям. В результате таких классификаций предлагается различать отношения, организующие применение вспомогательных репродуктивных технологий, собственно отношения вспомогательных репродуктивных технологий и отношения, завершающие программу вспомогательных репродуктивных технологий. В статье поддерживается предложение о принятии специального нормативно-правового акта о применении вспомогательных репродуктивных технологий, в предмет регулирования которого должны войти только специфичные общественные отношения.

The article examines the relations that arise during application of the assisted reproductive technologies. They are considered as an integrated complex of social relations. Some classifications of such relations are proposed based on the grounds known to the Russian domestic doctrine, as well as on the special grounds that can be applied to these specific relations only. It is suggested to distinguish between relations arranging ART application, ART relations as such and relations finishing ART programs. The author supports the idea of adoption of a special statutory instrument concerning ART application, which subject of regulation shall include only specific social relations.
ИЗУЧЕНИЕ ЗАПАДНОЕВРОПЕЙСКОГО ПРАВА И ЗАПАДНОЕВРОПЕЙСКОЙ ГОСУДАРСТВЕННОСТИ В РАБОТАХ Ф. В. ТАРАНОВСКОГО
Authors: Гончарова Е.А.
Published: December 2024

Данная работа исследует труды Ф. В. Тарановского, посвященные развитию западноевропейского права. Методы, использованные ученым, можно использовать и в современных реалиях. Как сторонник социологического позитивизма, Тарановский уделял внимание развитию правовых институтов с нескольких сторон: со стороны деятельности государства, со стороны жизни общества; пытался не только проанализировать правовые источники, но и объяснить, почему они появились. Социологический позитивизм не теряет востребованности и в наше время, ведь такое многообразие подходов в сочетании со сравнительно-историческим методом позволяет прогнозировать будущий правовой климат.

This paper examines the works of F.V. Taranovskiy dedicated to the development of the Western European law. The methods used by the scientist can also be used in modern realities. As a supporter of sociological positivism, Taranovskiy paid attention to the development of legal institutions from several points of view: from the side of the state, from the side of society; he tried not only to analyze legal sources but also to explain why they appeared. Such a variety of approaches combined with a comparative historical method makes it possible to predict the future legal climate.
АКТУАЛЬНЫЕ ПРОБЛЕМЫ РЕАЛИЗАЦИИ ПРАВА НА ПРИНЯТИЕ НАСЛЕДСТВА: СОВРЕМЕННОЕ СОСТОЯНИЕ И ПЕРСПЕКТИВЫ РАЗВИТИЯ ГРАЖДАНСКОГО ЗАКОНОДАТЕЛЬСТВА
Authors: Путилина Е.С.
Published: December 2024

В статье исследуются правовые особенности реализации права на принятие наследства в современный период. Определены юридические признаки, характерные для акта принятия наследства, исследованы и проанализированы различные доктринальные позиции по существу теоретических и практических аспектов реализации права на принятие наследства. Выявлены актуальные проблемы реализации права на принятие наследства в современный период, сформулированы конкретные предложения и рекомендации, направленные на развитие гражданского законодательства, регламентирующего особенности реализации права на принятие наследства.

The article examines the legal features of implementation of the right to accept the inheritance in the modern period. Legal features characteristic of the act of accepting inheritance are defined, various doctrinal positions on the essence of theoretical and practical aspects of implementation of the right to inheritance are examined and analyzed. The actual problems of implementation of the right to accept the inheritance in the modern period are revealed, concrete proposals and recommendations are formulated aimed at development of the civil legislation regulating the features of implementation of the right to inheritance.
ТЕНДЕНЦИИ И ПРОБЛЕМЫ РАЗВИТИЯ РОССИЙСКОЙ АКАДЕМИЧЕСКОЙ НАУКИ В СОВРЕМЕННЫХ УСЛОВИЯХ
Authors: Казарина Л.А. , Казарина М.В.
Published: December 2024

В статье рассматриваются актуальные проблемы современной российской сферы науки академического сектора как важной составляющей социально-экономической системы государства. Развитие сферы науки является одним из наиболее приоритетных направлений национальной политики России и служит определенным драйвером ее роста и обновлений. Анализируется уровень развития науки с позиции различных статистических данных. Рассмотрены первые результаты и последствия проведения реформы РАН. Выявлены факторы, влияющие на академическую науку. Проведена оценка ее состояния на современном этапе. Даны отдельные рекомендации по улучшению состояния академической науки.

The article examines the actual problems of modern academic sector of Russian scientific sphere as an important component of social and economic system of the state. Development of scientific sphere is one of the most priority directions of the Russian national policy and it serves as the certain driver of its growth and updating. The level of development of science is analyzed from a position of various statistical data. The first results and consequences of carrying out the reform of the Russian Academy of Sciences are presented. The factors influencing development of the academic science are revealed. The assessment of its condition at the present stage is conducted. Certain recommendations about improvement of the academic science condition are given.
ПРОИЗВОДИТЕЛЬНОСТЬ ТРУДА КАК ОСНОВА ЭФФЕКТИВНОСТИ ФУНКЦИОНИРОВАНИЯ ОРГАНИЗАЦИИ
Authors: Петрякова С.В. , Радионова С.В. , Горбунова О.С.
Published: December 2024

Проблема производительности труда всегда занимала весомое место в условиях любой общественно-экономической формации. Именно с ее исследованием связывают понимание сущности и значимости социально-экономического прогресса, оценку перспектив развития и эффективности экономики организации. Непосредственно сам уровень производительности труда служит ярким индикатором возможностей и перспектив предприятия и общества. В целях повышения эффективности деятельности организации необходимо увеличение производительности труда, а именно разработка действенного механизма управления трудовыми ресурсами.

The problem of labor productivity has always occupied a significant place in any socio-economic formation. It is its research that links the understanding of the essence and significance of social and economic progress, evaluation of the prospects of development and efficiency of the organization’s economy. The level of labor productivity directly serves as a bright indicator of capabilities and prospects of the enterprise and society. In order to improve efficiency of the organization it is necessary to increase productivity, namely the development of an effective mechanism of human resources management.