bluuebunny/crossref_metadata_2025 huggingface dataset:
Studies on Drug Compatibility with different Pharmaceutical excipients in Nanoparticle Formulation
Authors: Devi R. , Komala M. , Jayanthi B.
Published: September 2022

Aim: This study determine the consistency of Lamotrigine with various drug formulations using the testing procedures such as differential scanning calorimetry and Fourier Transform Infrared Mass spectrometry. Method: Possible strong interactions between the drug and excipients affect the molecular nature, stability, and bioavailability of drugs, affecting therapeutic efficacy and protection. To see if there was a connection, the FTIR spectrum and DSC thermograms of raw drug, excipients, or drug-excipient mixtures were evaluated. Results and Conclusion: The drug had not come into contact with the excipients, according to the facts. Either of the excipients were mostly found to be consistent with the medication and can be used in the production of novel formulations based on the results obtained from DSC and FTIR.
Efecto de celulasas y xilanasas sobre la digestibilidad in vitro de la broza de espárrago (Asparagus officinalis), panca de maíz (Zea mays) y cáscara de maní (Arachis hypogaea) en rumiantes
Authors: Macías-Rodríguez Edis Geovanny , Gómez-Bravo Carlos Alfredo , Álava-Moreira Jimmy Roberto , Hurtado Ernesto Antonio
Published: September 2022

Los residuos de cosecha juegan un papel importante en la producción animal a nivel mundial. Aumentar el potencial nutricional de opciones de baja calidad con enzimas fibrolíticas mejoraría la digestibilidad y la utilización del forraje. Utilizando un método in vitro se evaluó el efecto de celulasas (EC:3.2.1.4) y xilanasas (EC:3.2.1.8) aplicados a cuatro niveles: 0 (control); 2.000; 4.000 y 8.000 UI·kg-1 MS en panca de maíz (PM), broza de espárrago (BE) y cáscara de maní (CM). Al aplicar celulasas a la PM, la digestibilidad de la materia seca (DIVMS) y fibra detergente neutra (DIVFDN) fueron mayores (P<0,001) que el grupo de control (63,7 vs. 61,8 % y 51,9 vs. 50,1 %); efectos similares se encontraron con xilanasas (64,1 vs. 61,8 % y 53,0 vs. 51,6 %). La DIVMS y DIVFDN de la BE no fueron afectadas por la aplicación de celulasas o xilanasas (P<0,05). En el caso de la CM, la aplicación de celulasas o xilanasas mejoró la DIVMS (24,9 vs. 22,3 % y 24,6 vs. 22,3 %, respectivamente), pero no la DIVFDN. Además, la producción de gas in vitro a las 48 horas no fue influenciada por el tipo de enzimas ni por sus niveles de aplicación a los residuos evaluados. Las celulasas o xilanasas aplicadas sobre la PM y la BE no influyeron sobre la concentración de AGVt (acético + propiónico + butírico). En el caso de la CM, la concentración de AGVt fue similar entre el control y el aplicado con celulasas, mientras que la aplicación de xilanasas resultó en menor concentración de AGVt que el control. Las celulasas y xilanasas influencian la DIVMS, DIVFDN y la concentración de AGVt dependiendo del sustrato utilizado.
Defining Rampage Violence Across Completion Status: Towards a More Comprehensive Model
Authors: Hawes Janelle , Madfis Eric
Published: September 2022

The definitions and terms used to describe single-incident mass casualty events vary widely and remain contested. To allow for the inclusion of more incidents, larger and more representative samples, and more comprehensive analyses, we argue in favor of using the broad term “rampage” and propose a new model, the Rampage Violence Status Model (RVSM), which provides additional context on completion status and can subsume previous terminology. Additionally, by expanding upon previous researchers’ distinctions and definitions of various stages and completion statuses, we suggest adopting the following terms as stages in the progression of rampage violence, per the RVSM: researched, planned, prepared, initiated, interrupted, attempted, and completed.
IL SANTUARIO DI RAS IL-WARDIJA: LA PRIMA CAMPAGNA DI SCAVI 2021 DELLA MISSIONE ARCHEOLOGICA A GOZO DELL’UNIVERSITÀ DI ROMA «LA SAPIENZA»
Authors: Spagnoli Federica
Published: September 2022

The promontory of Ras il-Wardija, on the northwestern cusp of the island of Gozo, holds one of the most spectacular temples of ancient Mediterranean dedicated to the Phoenician goddess Astarte, the Great Goddess of sailors. The Phoenician-Punic sanctuary of Ras il-Wardija dates to the 4thcentury BC and hosts an important cult of Hera/Juno throughout the Roman period (3rd century BC-2ndcentury AD). Since its Phoenician construction, it was one of the main Mediterranean sanctuaries along the ancient sea-route called “Route of the Great Islands” connecting the East and the West of the Mediterranean. The general plan of the sanctuary has been clarified by the excavations of the Italian Expedition that operated in the site between 1963-1967. However, a further investigation of the structures with respect to the territory behind it, a deep analysis of rites and cults worshipped in the sanctuary, and the overall chronology are still missing. Sapienza University, thanks to a new agreement with Heritage Malta and the Superintendence of Cultural Heritage of Malta, and with the collaboration of the University of Malta, resumed the research activities at Ras il-Wardija, pursuing the study of the sanctuary and following new research paths, including the environment and the ancient landscape
Perception, Practices and Problems of School Improvement Program Implementation: The case of selected secondary schools in Hawassa City Administration, Ethiopia
Authors: Bore Yishak Hanchacha , Triegaardt PK (Paul)
Published: September 2022

The primary goal of this study was to investigate the practise and problems of school improvement programme implementation in Hawassa City Administration Government Secondary Schools, with a focus on perceptions, practices, and challenges that affect its proper implementation, and to find solutions to ensure the success of SIP in Hawassa City Administration Government Secondary Schools. A mixed study strategy that included both quantitative and qualitative data was used to accomplish this goal. The research was carried out at four secondary schools in the Hawasa City Administration. Teachers, administrators, school board members, PTA members, student councils, and Hawasa City Education Department officials were the primary data sources. The sample teacher respondents were chosen using a simple random sampling approach, whereas school boards, principals, vice principals, educational officers, SIC, and PTA members were chosen using a purposive sampling technique. The information was gathered through questionnaires, interviews, and focus groups. After collecting the data, it was processed using SPSS-V20 software and evaluated using descriptive statistics such as frequency, percentage, mean, standard deviations, and ranges. Furthermore, the t-test was employed to assess the association between teachers' and other respondents' replies to study variables. The study's findings revealed that the level of engagement of teachers, leaders, and parents in planning and executing SIP was low; the system for monitoring and evaluation used to support SIP implementation was unable to properly conduct SIP. Furthermore, the majority of the activities across the four domains were carried out at a moderate level. Overall SIP adoption was moderate as a result of the study's findings. A lack of a properly prepared plan for SIP implementation, a lack of proper understanding of SIP at the school level, a weak monitoring and evaluation system of SIP, a lack of leadership capacity, different organs of the school not properly understanding their role in SIP, a lack of sufficient stakeholder involvement in SIP, and a lack of attention for SIP were major factors that hampered SIP implementation. To address the challenges and improve the implementation of SIP, it was suggested that schools prepare adequate awareness-creation programs to ensure practical involvement of all stakeholders in SIP implementation, make school committees functional, and strengthen monitoring and evaluation of school improvement programme implementation.
Türk Vergi Hukukunda Vergi Kaçakçılığı Suçuna Yönelik Son Düzenlemeler: OECD’nin Birinci Küresel İlkesi Çerçevesinde Bir Değerlendirme
Authors: DAYIOĞLU ERUL Rana
Published: September 2022

Vergi suçlarıyla küresel düzeyde mücadelenin her geçen gün artan önemi doğrultusunda OECD, vergi suçlarıyla mücadelede on küresel ilke yayınlamıştır. Bu ilkeler, OECD’nin raporunda yer alan 33 ülke için incelenmiş ve gelişmekte olan ülkeler için örnek teşkil edecek nitelikte düzenlenmiştir. Çalışmada Türkiye’ye ilişkin olarak ise herhangi bir veri ya da düzenleme yer almamaktadır. Bu çalışmada, suç ve cezaların kanuniliği ilkesine dayanan ve diğer tüm küresel ilkeler için hukuki altyapı oluşturan birinci küresel ilkenin, Türkiye’de vergi kaçakçılığı suçuna ilişkin olarak yapılan son yasal düzenlemeler çerçevesinde incelenmesi amaçlanmıştır. Birinci küresel ilke; vergi suçları ve bu suçlara neden olan fiillerin tanımlanması, bu fiillerin genel ve özel kanunlarda yer alması, uygulanacak cezaların açıkça belirlenmesi, daha ağır suçlara daha ağır yaptırımların uygulanması, suç kanıtlanırsa cezai yaptırım uygulanması ve cezai yaptırımların fiili olarak uygulanması gibi bazı hukuki düzenlemeleri kapsamaktadır. İncelemeler sonucunda, raporda yer alan yabancı ülke örneklerinde olduğu gibi, Türkiye’de de vergi kaçakçılığıyla mücadelede birinci küresel ilkeye uygun düzenlemelerin yer aldığı sonucuna ulaşılmış; daha etkin mücadele için birtakım öneriler sunulmuştur.
Hızölçer Genişband Sismometrelerde, Sismik Sinyal Neden Doyuma Ulaşır?
Authors: TUNÇ Süleyman , TUNÇ Berna , ÇAKA Deniz
Published: September 2022

Deprem izlemede kullanılan hız algılayıcılarının dinamik aralıkları 165dB civarında olmasına rağmen, şiddetli deprem dalgalarının oluşturduğu yer hareketi hızı aşırı güçlü olduğundan, bu cihazların ürettiği veriler, kırpılmakta ve kullanılamaz hale gelmektedir.

Ulusal ölçekte, depremleri gözlemleyen Türkiye’deki en önemli kurulumlar, Boğaziçi Üniversitesi Kandilli Rasathanesi ve Deprem Araştırma Enstitüsü (KRDAE) ile Afet ve Acil Durum Yönetimi Başkanlığı (AFAD) genişband sismometre kullanmaktadır. Van yakınlarında, 23.10.2011 tarihinde meydana gelen depremde (Mw=7,2) genişbant sismometrelerin kaydettiği dalga şekli verilerinin çoğu doyuma ulaşması sonucu, sinyalin üstten ve/veya alttan kırpılmasıyla depremin büyüklüğü ve yerinin belirlenmesi konusunda bazı sıkıntılar yaşanmıştır. Ülkemizde, genişband sismometreler doyuma ulaşmaz inanışını değerlendirmek amacı ile algılayıcıların neden doyuma ulaştıkları hakkında bulgular verilecektir.
Pişirime Uygun Duvar Karosu Üretiminde Şeker Sanayii Atıklarının Değerlendirilmesi
Authors: ERCİOGLU AKDOĞAN Nihan , UBAY Elif
Published: September 2022

Bu çalışmada, kalsit yerine kalsiyum oksit içeriği yüksek olan (%45,84) şeker pancarı filtre pres atıklarının duvar karosu üretimindeki kullanılabilirliği incelenmiştir. Bu sayede, şeker üretimi sonrası açığa çıkan ve yığınlar oluşturarak çevreyi kirleten şeker üretim atıklarının, ticari ürünlerin üretilirken kullanılması sağlanarak atık malzemelerin çevreye zararları önlenebilmektedir. Aynı zamanda kalsit hammadde rezervlerindeki azalmanın önüne geçmek için alternatif oluşturubilecek potansiyale sahiptir. Daha önce herhangi bir seramik fabrikası tarafından duvar karosu üretimi için böylesine kritik bir hammaddenin, bir atıktan karşılanmaması çalışmanın özgün ve yenilikçi yönünü ortaya koymaktadır. Bu amaç doğrultusunda, Eskişehir Şeker Fabrikası’ndan, şeker üretim prosesinin ikincil kireçleme adımında atık olarak ortaya çıkan filtre pres keki kullanılmıştır. Atık malzemenin XRF, XRD, TGA, tane boyutu dağılımı ve rutubet analizleri yapılmıştır. Elde edilen sonuçlar, ticari olarak kullanılan kalsit ile karşılaştırılmıştır. Bunlara ek olarak, standart duvar karosu reçetesine kalsit yerine kütlece %6-%12 oranları arasında atık pres keki ilavesiyle üretilmiş karoların, pişme küçülme, üç nokta eğme, su emme, küçük renk farklılıkları TSE standartlarına göre karşılaştırılmıştır. Bu karşılaştırmalara göre %6 atık içeriğine sahip olan duvar karolarının mukavemeti 182,48 kg/cm2 olarak hesaplanmış olup diğer fiziksel testleri de olumlu sonuç vermiştir. Ayrıca atık malzemenin, sürekli üretim sistemine entegrasyonunun sağlanması için de atık malzemenin değirmene şarj edilme yöntemleri araştırılmıştır.
Değişken Hız Sürücüsü İle Tahrik Edilen Elektrik Motorlarında Enerji Verimliliği Tespitine Yönelik Ölçüm Yöntemleri ve Standartları
Authors: BÜYÜK Serdar , ÖZDEMİR Engin
Published: September 2022

Şebeke ile beslenen ve Değişken Hız Sürücüsü (DHS) ile beslenen elektrik motorlarının verimini tespit etmek için IEC tarafından yayımlanan standartlarda test ve ölçüm metotları tarif edilmiştir. İlk olarak 2007 yılında yayımlanmış olan ve şebeke ile beslenen elektrik makinelerinin verim tespit metotlarını içeren IEC 60034-2-1 standardı üzerinde hâlihazırda laboratuvarlar, akademisyenler ve üreticiler geniş bir tecrübe kazanmıştır. DHS ile tahrik edilen elektrik motorlarının verim tespiti ve kayıpları ile ilgili literatürde çalışmalar bulunmaktadır. Ancak DHS ile tahrik edilen motorların verim tespiti metotlarını içeren IEC 60034-2-3 standardı 2020 yılında yayımlanmış ve bu metotlarla ilgili olarak IEC 60034-2-1’deki kadar geniş bir birikim bulunmamaktadır. IEC 60034-2-3 testleri için, IEC 60034-2-1’deki temel donanımlara (dinamometre veya yük motoru, tork ve devir sensörü, en az 3 kanallı güç ölçer, sinüzoidal güç kaynağı) ek olarak standartta tanımlanan referans sürücüye ve 6 kanallı bir güç ölçere ihtiyaç vardır. Ölçüm metotları da temelde IEC 60034-2-1 ile benzerlik göstermektedir. Bu nedenle mevcut altyapılar yeni standarda göre modernize edilebilir. DHS ile yapılacak testlerde elektrik motorunun verim tespiti için 4 adet ölçüm metodu belirlenmiş ve bunlardan ikisi standart tarafından “tercih edilen metot" olarak tanımlanmıştır. Bu çalışmada bu metotların uygulamaları üzerinde değerlendirme ve bir örnek hesaplamanın uygulaması yapılmaktadır.
F. BUSONI IN RUSSIA: TO THE QUESTION ABOUT THE MOSCOW PREMIERING OF THE OPERA HARLEQUIN, OR WINDOWS
Authors: У Сянцзэ
Published: September 2022

В статье рассматривается премьерная постановка оперы Ф. Бузони «Арлекин, или окна» (1913-1916). Анализируется режиссерский замысел и его воплощение творческой труппой театра. Подчеркивается, что показанное на сцене «Геликон-оперы» творение Ф. Бузони (Москва, 2022 год) обнаруживает точки соприкосновения с другой постановкой - оперой Д. Лигети «Великий Мертвиарх» (1973-1977). Ее показ состоялся на сцене театра «Лисеу» (Барселона, 2011 год). Исследуется наличие параллелей в эстетических взглядах двух художников, которые одинаково ярко обнажают пороки современного общества. Отмечается, что сравнительный анализ постановочных версий обеих опер показал, что при сходных проблемах, напрямую связанных с современной социокультурной ситуацией, московская постановка грешит вторичностью визуальных приемов, обнаруживая черты пошлости и дурновкусия.

The article deals with the premiere production of F. Busoni's opera “Harlequin, or Windows” (1913-1916). The author analyzes the director's idea and its implementation by the theater's creative troupe. It is emphasized that the creation of F. Busoni (Moscow, 2022) shown on the stage of the “Helikon-Opera” finds points of contact with another production - the opera “The Great Deadviarch” (1973-1977) by D. Ligeti. Her show took place on the stage of the theater “Liceu” (Barcelona, 2011). The author examines the presence of parallels in the aesthetic views of the two artists, which equally clearly expose the vices of modern society. It is noted that a comparative analysis of the staging versions of both operas showed that with similar problems directly related to the modern socio-cultural situation, the Moscow production sins with secondary visual techniques, revealing features of vulgarity and bad taste.
Concepções de ciências de futuros professores da área das ciências da natureza
Authors: Arten Ygor , Ramos Italo , Corte Viviana , Araújo Michell , Genovese Cinthia
Published: September 2022

Um indivíduo constitui-se subjetivamente por meio das relações culturais que mantém com seu grupo social, tornando-se um sujeito único. Nesse sentido, objetivou-se identificar a influência de diferentes fontes de conhecimento sobre as concepções de ciência dos futuros educadores da área e o impacto delas no processo de ensino. No estudo, foram aplicados 174 questionários para alunos de licenciatura dos cursos de Ciências na Universidade Federal do Espírito Santo. O questionário consistia em 10 histórias que enunciavam fenômenos da natureza, em que cada indivíduo deveria assinalar se “concordava” ou “discordava” com aquela explicação. Na sequência, era solicitado que escolhessem a origem daquela concepção. Os resultados, à luz da perspectiva histórico-cultural de Vigotski, revelaram que, a opnião pessoal (P) sobressaiu (50,30%) entre os outros tipos de conhecimento como o científico (30,50%), e as demais fontes (19,20%). Desta feita, os futuros educadores da área de ciências necessitam refletir acerca das possibilidades de que suas convicções pessoais interfiram no processo de ensino e aprendizagem, bem como na compreensão sobre os fenômenos naturais, oriundas de sua constituição sociocultural.
A review on nanomedicines in treatment of thyroid and their applications in management of thyroid disorders
Authors: Pund Swati , Chandak Raman , Rajurkar Vikas , Kharat Nitin , Khalil Shaikh Sohel Shaikh , Shaikh Shoebuddin , Parve Kishor , Kadam Manohar , Choudante Shubham , Pulate Chetan , Wakale Vijaykumar , Tare Harshal
Published: September 2022

Thyroid disease is a major issue all over the world. Thyroid illness is also very common in India. Numerous thyroid disease studies have revealed that 42 million Indians are affected by the disease. Thyroid ailments are classified into five types in India: hypothyroidism, hyperthyroidism, goitre and iodine deficiency disorders, Hashimoto's thyroiditis, and thyroid cancer. The epidemiology of these five diseases will be the subject of this review. Thyroid hormone replacement therapy has been used to treat hypothyroidism for over a century. For the majority of the twentieth century, the first pharmacological treatments were natural thyroid preparations (thyroid extract, desiccated thyroid, or thyroglobulin), which contained both thyroxine (T4) and triiodothyronine (T3) (T3). This article discusses briefly the current treatment options for common thyroid issues.
contribution of some kinematic variables to the stages of the triple jump performance at the level of achievement
Authors: Al-Jaber Karim Abdul Hussein , Shandal Basma Abdul Hussein
Published: September 2022

The significant development and high achievement that occurred for Olympic and world athletics in the late twentieth century and the beginning of the second millennium in recording advanced records for all events, including (throwing, jumping, and running short, medium and long distances) came as a result of continuous training, experience and field practice, and reliance on the latest Scientific techniques and applied sciences, including biomechanics, "the science that is concerned with studying human movements and analysing them quantitatively and qualitatively to increase the efficiency of human movement, and to identify the causes of action and its phenomena. The triple jump is one of the field activities in addition to the effectiveness of the long jump, which requires performance from The contestant must perform, according to the competition law, the technical stages (approximate run - hopscotch - step - jump) on the jump field. As a result of the digital development of this event, the importance of this study came to identify which kinematic variables have an impact and a significant contribution to the level of achievement and for each stage of performance Triple jump among the best riders of the World Championships that took place in Berlin 2009.
relationship of manifestations of attention in some basketball skills among female students of physical education and sports sciences
Authors: Abdalla Ahlam Najm , Qassem Dina Hammoud
Published: September 2022

The study aimed to identify the relationship between the manifestations of attention and the accuracy of the skill of handling and shooting basketball for female students. As for the research sample, the research community was identified as students of the College of Physical Education and Sports Sciences - University of Al-Qadisiyah for the academic year 2021-2022. Their number is (39) students, where the proportion of the sample from the community reached 100%. In light of the preceding, the results were a positive relationship between the concentration of attention and the skills of free and peaceful scoring among students of physical education and sports sciences, as well as a positive relationship between the intensity of attention and the skills of free and peaceful scoring among students of physical education and sports sciences.
Aesthetic and educational values in Hussein Ali Haref texts for boys
Authors: Mustafa Ali Habeeb , Hassan Mudhad A.
Published: September 2022

After reviewing a series of texts of the play directed at the boys by the writer Hussein Ali Harf, the researcher noted the aesthetic and pedagogical values dictated by these theatrical texts and to shed scientific light on them. The research consisted of four chapters. Chapter I contained a presentation of the research problem, which revolved around answering the following question: (What are the aesthetic and pedagogical values in the texts of Hussein Ali Harf for boys). The present research aims to reveal the aesthetic and educational values in the texts of the boys' theatre. Chapter II contains the theoretical framework, with three investigations, the first research: Aesthetic Values, Research II: Educational Values, Research III: Aesthetic and Educational Values in Boys' Theatre Texts and Chapter II concluded with Theoretical Framework Indicators Chapter 3 contains the research curriculum and procedures, since the current research aims to reveal the aesthetic and educational values in the texts of Hussein Ali Harf. The researcher has adopted the analytical descriptive curriculum as a methodological framework for building his research procedures as it is the most suitable scientific curriculum for achieving the research goal.
Perspective of health workers on tourism health problem in the working area of Nipah health center North Lombok District
Authors: Karmila Dany , Utami Sukandriani , Anulus Ayu , Mardiah Aena
Published: September 2022

The West Nusa Tenggara Province (NTB) is designated as a Special Economic Zone (SEZ), where the direction of development is tourism. North Lombok is one of the districts with a developing tourist area. The tourist areas of North Lombok regency are mostly located in the working area of ​​the Nipah Health Center.Tourism can have both positive and negative impacts. One of them is tourism health problem. This study aims to determine the perspective of health workers related to tourism health problems in the working area of ​​the Nipah Health Center. Researchers used qualitative research design with a phenomenological approach. The researcher used purposive sampling technique with data collection method using observation and in-depth interviews with the five informants. The results of the study based on the perspective of health workers in the working area of ​​the Nipah Health Center showed tourism health problems including sunburn, heat stroke (physical hazard), food poisoning (chemical hazard), insect bites, mosquitoes and food contamination by flies (biological hazard) and traffic accidents. , drowning, impaled by marine animals such as sea urchins, jellyfish (mechanical hazard). Prevention and handling carried out include free health checks, counseling, formation of Disaster Preparedness Team (TAGANA) and coordination with related parties.
impact of pandemic on donors at PMI Semarang City in 2019-2021
Authors: Christanti Jessica , Kartika Anna , Susianto Indra Adi , Ariosta Ariosta
Published: September 2022

Globally, the Blood Donor Unit service has had a significant impact during the Coronavirus Disease-19 (COVID-19) pandemic. A significant impact occurred on donor recruitment due to the many considerations for donors during the pandemic. Changes in donor characteristics data before the pandemic and during the pandemic may occur. Therefore, researchers analyzed the impact of the pandemic on donors at Blood Donor Unit (Indonesian Red Cross, Semarang City, 2019 to 2021. Subjects and Methods: A study with a cross sectional design was conducted at Blood Donor Unit PMI Semarang. Secondary data collection consisting of voluntary blood donor form data from 2019 to 2021. The data were analyzed by One-Way Anova and Kruskal-Wallis with SPSS version 25. The study showed a significant decrease in age categories, namely < 18 years, 18-24 years and 25 -44 years and repeat donors in 2021 with 2019 and 2020 with 2019 (p < 0.05). There was a significant decrease in first-time donors in 2021 with 2019 and in 2020 with 2019 (p < 0.001). However, there was an increase in donors in the >60 year age category in 2020 and 2021 by 18.6% and 42% compared to 2019 although not statistically significant.
Fluids and Melts at the Magmatic-Hydrothermal Transition, Recorded by Unidirectional Solidification Textures at Saginaw Hill, Arizona, USA
Authors: Bain Wyatt M. , Lecumberri-Sanchez Pilar , Marsh Erin E. , Steele-MacInnis Matthew
Published: September 2022

Fluid exsolution and melt evolution at the magmatic-hydrothermal transition are critical processes driving the metal enrichment of porphyry systems. Coeval fluid and melt inclusion assemblages in unidirectional solidification textures (USTs) at Saginaw Hill—a small, porphyry Cu system in southwestern Arizona—record a dynamic and repetitious process of fluid accumulation and release. The cores of quartz crystals throughout the UST bands host coeval silicate melt and brine inclusions but lack vapor-rich inclusions. This could indicate preferential expulsion of vapor and trapping of high-density brine during episodes of fracturing or the direct exsolution of single-phase high-salinity brine from the silicate melt. In contrast, the rims of UST quartz host abundant coeval brine and vapor inclusions, consistent with liquid-vapor immiscibility at lower pressures compared to the corresponding quartz cores. This transition from dominantly coeval silicate melt inclusions and brine in phenocryst cores to coeval brine and vapor in the rims suggests that the Saginaw Hill system underwent cyclic processes of fluid exsolution, accumulation, overpressure, and decompression at relatively stable temperatures (consistently ~650°C) during UST formation. Melt inclusion data indicate that the melt at this stage was highly fractionated and tended toward muscovite saturation. Metal concentrations in the brine were comparable to or higher than those in fluids reported in world-class porphyry Cu systems and were likely the result of both igneous fractionation and the high chloride content of the exsolved fluids. While limited in scale, Saginaw Hill provides evidence for processes that are predicted to occur at the magmatic-hydrothermal transition during the formation of large, well-mineralized porphyry systems.
Experiencia en la aplicación del aprendizaje basado en proyectos
Authors: Canales Hilde Obermöller , Narbona María Francisca Soto , Villarroel Peter Bravo
Published: September 2022

Se describe el desarrollo y ejecución del trabajo realizado en conjunto por las asignaturas de Taller de Integración UV I y Gestión de Eventos, ambas asignaturas del segundo ciclo de formación de la Carrera de Administración Hotelera y Gastronómica de la Universidad de Valparaíso, donde se aplicó el aprendizaje basado en proyectos. Mediante esta metodología los estudiantes integraron el trabajo en aula y la interacción con la comunidad, resultando una estrategia útil para generar vinculación con el medio y potenciar el desarrollo de competencias requeridas para el desempeño de los futuros profesionales que forma la Universidad.
A Novel Metaheuristic Optimization based Clustering with Routing Scheme for IoT Mobile Edge Computing Platform
Authors:   Nova Information Management School, Universidade Nova de Lisboa, 1070-312, Lisboa, Portugal, Abdelaziz Ahmed ,   Nova Information Management School, Universidade Nova de Lisboa, 1070-312, Lisboa, Portugal, Mahmoud Alia N.
Published: September 2022

Largescale IoT applications with thousands of geo distributed IoT gadgets making huge volumes of data impose immense challenges to designing transmission mechanisms that offer data transfer has less latency and great scalability. In this work, an investigation of a hierarchical Edge-Cloud publishes or subscribe brokers method was performed with the help of an effective two-tier routing structure for alleviating such problems whenever sending event notices in large scale IoT mechanisms. In this technique, IoT gadgets use the benefits of nearby edge brokers deliberately positioned in edge network for data supplying services for minimizing latency. This manuscript introduces a Novel Metaheuristic Optimization based Clustering with Routing Scheme for IoT Mobile Edge Computing Platform, named MOCRS-IoTMEC model. The projected MOCRS-IoTMEC model is mainly concentrated on the identification of optimal routes in the IoT assisted MEC environment by the use of pigeon inspired optimization (PIO) algorithm. Also, the LEACH protocol is applied to initially cluster the IoT devices. The PIO algorithm is applied to determine the fitness function to choose optimal routes. To depict the enhanced performance of the MOCRS-IoTMEC model, a detailed comparison study is made. The experimental outcomes reported the enhanced execution of the MOCRS-IoTMEC method over other approaches.
Clustered IoT Based Data Fusion model for Smart Healthcare Systems
Authors:   Nova Information Management School, Universidade Nova de Lisboa, 1070-312, Lisboa, Portugal, Abdelaziz Ahmed ,   Nova Information Management School, Universidade Nova de Lisboa, 1070-312, Lisboa, Portugal, Mahmoud Alia N.
Published: September 2022

Futuristic sustainable computing solutions in e-healthcare applications were depends on the Internet of Things (IoT) and cloud computing (CC), has provided several features and realistic services. IoT-related medical devices gather the necessary data like recurrent transmissions in health limitations and upgrade the exactness of health limitations all inside a standard period. These data can be generated from different types of sensors in different formats. As a result, the data fusion is a big challenge to handle these IoT-based data. Moreover, IoT gadgets and medical parameters based on sensor readings are deployed for detecting diseases at the correct time beforehand attaining the rigorous state. Machine learning (ML) methods play a very significant task in determining decisions and managing a large volume of data. This manuscript offers a new Hyperparameter Tuned Deep learning Enabled Clustered IoT Based Smart Healthcare System (HPTDLEC-SHS) model. The presented HPTDLEC-SHS technique mainly focuses on the clustering of IoT devices using weighted clustering scheme and enables disease diagnosis process. At the beginning level, the HPTDLEC-SHS technique exploits min-max data normalization technique to convert the input data into compatible format. Besides, the gated recurrent unit (GRU) model is utilized to carry out the classification process. Finally, Jaya optimization algorithm (JOA) is exploited to fine tune the hyperparameters related to the GRU model. To demonstrate the enhanced performance of the HPTDLEC-SHS technique, an extensive comparative outcome highlighted its supremacy over other models.
Utilização de Instrumentos Tecnológicos na Efetividade da Aplicação da Lei Maria da Penha (Lei Nº 11.340/06) na Contemporaneidade Brasileira
Authors: Torres Daniel Chagas , Rodrigues Renata David Nunes
Published: September 2022

O presente trabalho aborda o estudo da utilização de instrumentos tecnológicos como mecanismos de efetividade da lei Maria da Penha (Lei nº 11.340/2006), no que diz respeito à proteção de mulheres vítimas de violência doméstica, com fito de suprir as carências estatais, materiais e humanas, afastando qualquer possibilidade de não prestação estatal policial relacionada ao princípio da reserva do possível. A relevância do tema é crescente, justamente pelos alarmantes dados de aumento progressivo dos casos de violência doméstica, especialmente no período posterior à pandemia de COVID19, o que justifica um estudo acadêmico, jurisprudencial e doutrinário. Dentro dessa perspectiva, a partir de uma pesquisa dedutiva, com apoio nos procedimentos bibliográficos – livros e artigos de revistas – e documental, conclui-se que elementos de tecnologia como botões de pânico, sincronização do monitoramento de tornozeleiras eletrônicas, geolocalização da vítima e do agressor, aplicativos de celular relacionados aos casos de violência, acesso facilitado a informações úteis pela internet, instrumentos de comunicação tecnológicos com as autoridades policiais e outros meios podem ser ferramentas valiosas para a efetividade da lei Maria da Penha.
Heavy metals concentration in undisturbed peat soil at Pekan District, Pahang, West Malaysia
Authors: Abdul Wahab  , Muzamir Hassan  , Zaheer Ud Din  , Qamar Uz Zaman
Published: September 2022

Soil is a mixture of various materials such as air, water, and organic matter. Soft soil (peat) has very deprived physical properties such as low shear strength, high moisture content, high compressibility, and permeability. In an engineering perspective it is considered as a weak soil, while an the agricultural context it is considered as a rich soil because of high amount of carbon. Heavy metals such as arsenic, chromium, cadmium, and lead are considered highly toxic, and it may produce mutagenic, carcinogenic, and genotoxic effects. This study examined the heavy metals concentration of peat soil. There were nine peat samples collected from three different sites which are Kampung Bahru (KB), Kampung Lancang I (KL I), and Kampung Lancang II (KL II), Pekan district, Pahang State, Malaysia. This research indicated that the average organic content were 97.8 % for KB, 95.88 % for KL I, and 98.48 % for KL II approximately for peat soil. It concluded that the concentration of As, Cu, Ni, Pb, and Zn exceeded the standard guidelines, and Mg concentration was observed below the recommended guidelines. It is essential to extract these metals and further assess their toxicological impact on the environment and human health.
THE THEORY OF ULTRA - GROUPS and GAP APPLICATIONS
Authors: SOYLU YILMAZ Elis , EGE ARSLAN Ummahan , KUNDAKÇIOĞLU Şahika
Published: September 2022

In this work, we introduce a system computational programming of the ultra-group notions with GAP, Groups, Algorithms and Programming. We have constructed some algorithms about ultra-groups and their substructures with GAP language. Also, we give the GAP algorithm about ultra-group homomorphism. So we have presented a GAP application for ultra-group theory.
A Novel Mobile App-based Neuromuscular Electrical Stimulation Therapy for the Management of Knee Osteoarthritis: Results From an Extension Study of a Randomized, Double-blind, Sham-controlled, Multicenter Trial
Authors: Dasa Vinod , Skrepnik Nebojsa V. , Petersen Dena , Delanois Ronald E.
Published: September 2022

Background:

Mobile app-based neuromuscular electrical stimulation (NMES) is a promising treatment of knee osteoarthritis as previously demonstrated in a 12-week, randomized, double-blind, sham-controlled, multicenter trial (parent study).

Methods:

Sixty-four of the 253 patients with knee osteoarthrosis who completed the 12-week parent study were enrolled in a 14-week extension study during which they continued to receive double-blind, home-based NMES (two 20-minute daily sessions, 5 d/wk) with either the original device (“active NMES”) or a low-voltage version (“sham NMES”). All subjects who enrolled in the extension study comprised the intent-to-treat population and subjects who applied NMES (compliance monitored through the mobile app and a remote portal) for at least 2,800 minutes (14-week device usage) comprised the per-protocol therapy compliant population.

Results:

In the per-protocol therapy compliant population, the active NMES group (n = 21) had a higher reduction in Visual Analog Scale Nominated Activity (64.7% versus 24.3%, P = 0.020) and Visual Analog Scale Nominated Activity improvement ≥50% (76.2% versus 12.5%, P = 0.002) than the sham NMES group (n = 8). Outcomes were not markedly different between groups in the intent-to-treat population.

Discussion:

Applying NMES therapy for an additional 14 weeks (totaling 26 weeks) resulted in notable and clinically meaningful pain relief when patients were fully compliant with NMES.
Keskintaş, Orhan. Adalet, Ahlâk ve Nizam Osmanlı Siyasetnameleri. İstanbul: İletişim Yayınları, 2017. 344 Sayfa. ISBN: 9789750522789
Authors: KELEŞ Ahmet
Published: September 2022

Bu yazı Orhan Keskintaş’ın Osmanlı siyasetnameleri hakkındaki doktora tezine dayanan Adalet, Ahlâk ve Nizam Osmanlı Siyasetnameleri adlı eseri tahlil etmektedir. Bölümlerin içeriği hakkında ayrı ayrı özet bilgiler verilmekte ve ardından genel bir değerlendirme yapılmaktadır. Son kısımda esere yönelik bazı olumsuz eleştiriler de eklenmiştir.
Ожирение и современные методы его лечения
Authors: Джндоян З. Т. , Петросян А. Г.
Published: September 2022

It is proven that obesity increases the risk of atherosclerosis and cardiovascular system diseases such as varicose disease, arterial hypertension, ischemic heart disease, stroke and myocardial infarction also diabetes mellitus, calculous cholecystitis, osteoarthrosis, sleep apnea syndrome, dyslipidemia, non-alcohol origin fatty heptoses, oncological diseases such as breast, uterus, ovarium cancer. It also decreases reproductive function. The mortality rate of people with severe obesity is 10 times higher than that of people without obesity. Patients with obesity firstly must be closely monitored by general practitioners, as well as by cardiologists, gastroenterologists, surgeons, rehabilitators, and nutritionists. There are two standard directions for treating obesity. They are: conservative, which is divided into 2 subgroups: non-pharmacological, that is, following strict diets, having physical activity, and medicinal, when certain groups of drugs are prescribed to depress the appetite center or to reduce the absorption of lipids from the intestines and affect their metabolism. The second way of treatment is surgery, which is used in extreme cases. A wide range of drugs allows us to hope that the correct and competent strategy with patients with obesity can reduce the consequences and complications caused by obesity.
Democracia paritaria en Ecuador: un análisis de los efectos del sistema electoral en las elecciones de 2021
Authors: Garzón-Sherdek Karen Andrea , Cahuasquí-Cevallos Santiago Manuel
Published: September 2022

Uno de los aspectos sustanciales de las últimas reformas a la Ley Orgánica Electoral y de Organizaciones Políticas de la República del Ecuador, Código de la Democracia (2009), promulgadas el 3 de febrero de 2020, fue la modifcación de tres de los elementos que conforman el sistema electoral ecuatoriano: forma de lista y forma de voto (art. 120), fórmula de adjudicación de escaños (art. 164), así como la promoción de la participación y representación política de las mujeres a través del encabezamiento paritario de listas (art. 99). En esta perspectiva, este artículo analiza el impacto de esta reforma indagando dos de los efectos del sistema electoral: (1) cómo los ciudadanos expresan su preferencia política por una opción partidaria (votos) y cómo esas preferencias se traducen en curules legislativas (escaños); y, (2) de qué forma inﬂuyen en los resultados electorales los criterios paritarios para el encabezamiento de listas pluripersonales.
Taizé e sua abertura ao diálogo inter-religioso: sua origem, seu viés ecumênico e suas práticas sociais
Authors: Gastão Patrícia Gurgel Medeiros
Published: September 2022

A comunidade de Taizé surge, historicamente, em um contexto pós-guerra como apelo a uma espiritualidade de fraternidade e amor aos irmãos, frente a uma sociedade em constantes conflitos, perseguições e mortes. Neste sentido, a presente pesquisa buscará se debruçar sobre a origem de Taizé, destacando seu viés ecumênico como abertura a uma mística de amor que entrelace o divino e os seres humanos, em comunhão, serviço e respeito. Por isto, também objetiva-se apresentar, como disposição ao diálogo com outras religiões, os projetos sociais protagonizados pela Comunidade em várias realidades, expressando uma práxis, fruto de uma espiritualidade sensível.
PERILAKU MASYARAKAT DALAM MENGGUNAKAN MEDIA DIGITAL DI MASA PANDEMI
Authors: Apdillah Dicky , Deri Afif , Wijaya Chandra Ridho , Sitorus Muhammad Aldi Prayuda
Published: September 2022

Indonesia is one of the countries affected by the Covid-19 outbreak. PolicyThe government regarding Large-Scale Social Restrictions (PSBB) has an impact on various sectors in Indonesia, be it the economic, entertainment, religious and education sectors. The need for understanding the use of digital media in the community will determine the mindset of the community in dealing with this pandemic. Educational activities that were stopped during the pandemic have been transformed into online learning by utilizing digital media. Ease of accessing all information through several applications in gadgets in people's lives, but not all people take advantage of these opportunities positively. The purpose of this study was to determine people's behavior in using digital media during the Covid-19 pandemic. The research method used is a literature review method based on literature exploration from the results of previous studies. These literatures are in the form of books, survey results, online media, and national research articles. The results of the study revealed that there were major changes in people's behavior in several aspects. The changes come from their own initiative as well as an appeal or order from the competent authority. In addition, the pandemic period affects people's mental and psychological health. Media has always been a social institution, during this pandemic, learning can be carried out using various platforms, both in the form of a learning management system and in the form of video conferencing so that parents and teachers are required to have digital literacy skills. The conclusion of the study is that the use of digital media greatly influences people's behavior, besides the ability to use digital media is needed by the community as a digital literacy effort during the Covid-19 pandemic.
Popularization of health in Polish philately
Authors: Smoła Marek
Published: September 2022

The article constitutes an attempt of presenting the phenomenon of popularization of health, health protection, achievements in medicine and people connected to medicine through a postal stamp. A stamp is an object of collection and the subject of the more and more elitist hobby but at the same time it is an element of correspondence used by many people, including a sender and a recipient in numerous countires.That is why, reaching for such a topic in different emissions of postal stamps can spread the knowledge about different almost all aspects of human civilization.This publication is a compilation of information about postal stamps issued by Polish Post Office between 1919 and 2022 and referring in multiple ways and methods to the widely understood topic of health and its protection. The aim of the work was to present the stamps in chronological order, including the emission title, circumstances and occasions of the emission, circulation numbers and short presentation of events, phenomena, people and objects depicted on the stamps.
Hentbolcularda Yaralanma Kaygısı Düzeyinin Farklı Değişkenler Açısından İncelenmesi
Authors: GÜLER Yunus Emre
Published: September 2022

Bu çalışmanın amacı, hentbolcularda yaralanma kaygısı düzeylerinin belirlenerek farklı değişkenler açısından spor yaralanması kaygı ölçeği alt boyut düzeylerinin karşılaştırılmasıdır. Lisanslı olarak hentbol oynayan ve çalışmaya dahil edilme kriterlerine uyan 164 kadın-erkek hentbolcu çalışmanın örneklem grubunu oluşturmuştur. Araştırma verileri demografik bilgi formu ve spor yaralanması kaygı ölçeği kullanılarak oluşturulan anket formu ile Google Doc ile online ortamda toplanmıştır. Verilerin analizinde öncelikli olarak verilere normallik analizleri uygulanmış ve verilerin normal dağılıma uyduğu belirlenmiştir. İki bağımsız grup arasında niceliksel sürekli verilerin karşılaştırılmasında Independent Sample T-Testi, ikiden fazla bağımsız grup arasında One-Way Anova testi kullanılmıştır. Değişkenler arasındaki ilişki düzeyinin belirlenmesinde ise Pearson Korelasyon testi uygulanmıştır. Test sonuçlarında cinsiyet, sporculuk düzeyi ve yaralanma bölgesi açısından yaralanma kaygısı alt boyutlarında anlamlı fark görülürken (p0,05). Ayrıca yaralanma süresi ile yaralanma kaygısı alt boyutları arasında ilişki olduğu görülmüştür (p
comicidad del primer Quijote y la aventura de los galeotes (Quijote I, 22)
Authors: Close Anthony
Published: September 2022

En el Primer Quijote la comicidad se basa en conflictos del protagonista con el mundo externo, ya que Cervantes pretendía burlarse de los libros de caballerías. El artículo se centra sobre todo en el episodio de los galeotes, que don Quijote quiere salvar de los trabajos forzosos y darles la libertad. Para brindar todo este humor a su obra, Cervantes se valió de otros géneros literarios y de obras que había leído y lo habían marcado en su juventud, incluso para la creación de algún personaje, como el galeote principal: Ginés de Pasamonte, un pícaro clásico. Asimismo, la imprevisibilidad de don Quijote y sus delirios continuos en las interacciones con otros personajes aportan comicidad a la novela.
ظاهرة العنف الأسري وأثرها على تدهور التماسك الاجتماعي (دراسة وصفية في ضوء مبادئ الإسلام والقانون الباكستاني الحالي)
The Phenomenon of Domestic Violence & Its Impact on the Deterioration of Social Cohesion (A Descriptive Study in the Light of the Principles of Islam & the Current Law of Pakistan)
Authors: Nawaz Muhammad , Arshad Muhammad
Published: September 2022

It is an incontestable fact that Islam emphasizes the importance of family integration and forbids entire acts that harm the significant integration of the family. Domestic violence is considered one of the harmful acts which affect on family environment in a deteriorating manner, it creates domestic conflicts which lead to the break-up of families. On the other hand, many efforts are being made for enacting laws and legislation in various countries. As for the efforts of Pakistan are concerned, many severe and extensive steps, initiatives and measures are being taken at the government level against the heinous and dreadful crime of domestic violence. This study explains the concept of domestic violence, and its types by focusing on the motives existing behind the exercise of domestic violence. This study also investigates the effects of domestic violence on family and community as it creates many physical and emotional problems like depression, anxiety, low self-esteem and phobia etc. It highlights Islam's teachings which contribute to finding solutions for protecting families from destruction and disintegration. Additionally, this study identifies to what extent extensive steps and wide-ranging measures are being taken against domestic violence which is exercised at different levels in various countries. A descriptive study has been carried out from the perspective of Islamic principles derived from the teachings of Islam and the current laws of Pakistan to prevent the people from domestic violence which is considered one of the heinous crimes prevailing in human society. This study ends with some findings and recommendations to get rid of the phenomenon of domestic violence to prevent families from destruction and disintegration by making efforts for creating social cohesion in human society.