bluuebunny/crossref_metadata_2025 huggingface dataset:
Proportion of hepatitis C virus antibodies in icteric patients
Authors: Layla Al-Omar S. , Faiza Mukhlis A. , Ramzia Al-Khayatt
Published: April 2022

A total of 1783 sera from icteric patients (988 male & 795 female), their ages ranged 8-54 years, were tested for the presence of viral hepatitis markers (hepatitis A, B, and C), using the available diagnostic kits (enzyme linked immunosorbant assay). 300 donor sera were also tested as matched control. Among the icteric patients 859 (48,2%) had evidence of acute hepatitis A (HA), 499 (28%) were found to be infected with hepatitis B (HB), and hepatitis C virus (HCV-Ab) was detected in 8.2% of patients that confirmed by recombinant immunoblot assay. The results indicated that the maximum HCV seroprevalence was found in patients more than 30 years old, and there was no difference in the chance of infection in both sexes. The main route of HCV transmission was observed in icteric patients who had received blood, and those underwent surgical intervention. These reflect the fact that some of transfused blood may contain HCV that could not be detected by routine serological tests used in Blood Bank. There is a need to identify HCV carriers and the increased awareness of medical and paramedical personnel regarding the risk of transmitting the disease iatrogenically. Furthermore the need to document the risk of nosocomial transmission and highlight the crucial role of molecular sequence based phylogenetic analysis of cloned viral isolates in the investigation of HCV infection.
Preparation and in-vitro evaluation of cilostazol self-emulsifying drug delivery system
Authors: Wannas Ali N. , Maraie Nidhal K.
Published: April 2022

This work reported a first liquid self-nanoemulsifying drug delivery system (SEDD) of cilostazol using oleic acid as oil phase, tween 80 as surfactant, and transcutol as co-surfactant. Cilostazol is a poor water-soluble phosphodiesterase III inhibitor, which has antiplatelet

 

and vasodilator effect used to relief intermittent claudication symptoms. Cilostazol solubility was determined in various oils, surfactants and co-surfactants and phase diagram was constructed at different oil: surfactant: co-surfactant ratios to determine the existence of nano-emulsion region. The in-vitro dissolution profile showed an optimized cilostazol SEDD formula (LT1) containing oleic acid (10%) as oil, tween 80 (45%) as surfactant, and transcutol (45%) as co-surfactant in comparison with the commercial conventionally Tablets. The LT1 formula was thermodynamically sTable, with a zeta potential of -30.48 mV and droplet size 154 nm. The LT1 capsule showed a superior dissolution profile (100%) when compared to the commercial Tablet (64%) of cilostazol.

The objective of the present study is to formulate cilostazol as an oral liquid SEDD with better solubility and drug release to overcome a variable bioavailability of the commercial Tablet in which a high-fat meal increases absorption to approximately 90%.
Clinical pharmacy in medical practice: the impact of detection, prevention and resolution of Drug Therapy Problems (DTPs) on patients with chronic diseases
Authors: Obeid Kawa A. , Ahmad Chiya Muhamad
Published: April 2022

(i). Background & objective: Recently, the role of pharmacists in the healthcare settings has dramatically evolved through the application of pharmaceutical care process. However, this new role has not been fully elucidated and reflected in the Iraqi healthcare system.  Therefore, the aim of this study was to evaluate the

 

impact of clinical pharmacist intervention on the management of patients with common chronic diseases. 

(ii) Methods: a randomised controlled trial study was performed with 125 patients with one or more of these conditions: hypertension, hyperlipidaemia and Diabetes mellitus. They have divided into two groups i.e. intervention and non-intervention groups. 

(iii) Results: The results revealed that pharmacist intervention played a significantly role in the management of chronic diseases given that a significant reduction in the various clinical parameters such as blood pressure, lipid profile, HbA1c and FPG were observed among the intervention group. Apart from development of a therapeutic relationship with the patients, these results are largely amounted to the detection, prevention and resolution of a massive number of DTPs among the patients in the intervention group.

(iv) interpretation & Conclusion: Clinical pharmacist intervention can play a pivotal role in the management of patients with chronic diseases. This could be extended to the other healthcare settings as well. Moreover, clinical pharmacist plays a key role in the achievement of therapeutical goals and avoiding Drug Therapy Problems (DTPs).
Effect of coating method on release of Glimepiride from porosity osmotic pump tablets (POPTs)
Authors: Abdulkhaleq Nuha Mohammed , Ali Wedad K. , Elkordy Amal A.
Published: April 2022

In this study, once-daily porosity osmotic pump tablets (POPTs) of Glimepiride were prepared using HPMC K100M (61%), osmotic agent (30% NaCl) coated using two different coating techniques spraying and dipping methods. The coating solution composed of ethyl

 

cellulose (7.5%) w\w in ethanol (90%), castor oil (2%) as water-insoluble plasticizer and Gingo red color (0.5% w\w). In both techniques, the coating level was adjusted to give a 10% increase in the weight of the tablets. The effect of the coating by dipping technique with an increase in the weight of tablet (10 %, 20% & 50%) was also investigated to see the effect coating level on the percentage of drug release from POPTs.

The results of the in vitro release of Glimepiride from tablets coated by the spraying method showed longer release time (24 hrs) than those coated with dipping method. On the other hand, increasing the coating level by dipping method retarded the release of the drug from tablets. However, the same retardation effect on release as shown with the spraying technique was only obtained by increasing the coating level with a 50% increase in the weight of the tablet. Thus, coating by spraying is more efficient to prepare POPTs to give a continuous release of Glimepiride from once daily table with the lowest increase in the total weight of the tablet.
Factors affecting preparation and evaluation of Kitorolac tromethamine microsponges for ocular use
Authors: Wid F. Neamah  , Nidhal K. Maraie
Published: April 2022

Ketorolac Tromethamine (KT) is prepared for the first time by double emulsion procedure. The current research involves preparation and evaluation of microsponges for ocular applications. This work included preparation of sixteen formulas of KT-microsponges by double

emulsion (w/o/w) method using poly lactic-co-glycolic acid (PLGA) as a polymer and poly vinyl alcohol (PVA) as a stabilizer, with different mixer types for different time and power. The prepared microsponges were characterized by Scanning Electron Microscopy (SEM) to investigate the morphology and particle size, the entrapment efficacy and percentage yield were calculated as well as in vitro drug release. Best formula (F14) of KT-microsponges had EE (74%), % yield (83%) with initial drug release (approximately 21% within the first fifteen days) which continued to reach (approximately 86% within 90 days) by using 30% of  PLGA  concentration with 0.05% of PVA and 200 ml of the external aqueous phase using a probe sonicator for 4 minutes at 200 Watt power. This formulation technique will be the interest of pharmaceutical company.
IDENTIFICATION OF QUERCETIN IN Echinops tenuisectus Family Compositae
Authors: KHADEEM ENAS JAWAD
Published: April 2022

This study is emphasized on the detection and identification of Quercetin Flavonoid in a newly studied, wild Iraqi plant, named Echinops tenuisectus of Compositae family. The medicinal importance of Quercetin on one hand, and the absence of any phytochemical investigation on tenuisectus specie of Echinops genus on the other hand, acquired this s importance. יstudy it Quercetin was identified in the plant extract of both, the aerial part’s and the seed’sextracts, by two chromatographic methods, first Thin Layer Chromatography (TLC) using TLC ready made Gf254 plates, UV detector at 254 nm, and tow different solvent systems in which the Rf value of the standard quercetin matched with the Rf value of the plant extract quercetin. HPLC was the other chromatographic method that proved the presence of quercetin in the plant extract by identical retention times. The result indicated that the quercetin content in the seed extract was higher than that in the plant extract of the aerial parts.
Assay of Metronidazole from Different Manufacturing Sources in Iraqi Markets
Authors: AL-SABEA N.
Published: April 2022

Metronidazole is an antibacterial agent that is effective in treatment of anaerobic infection. It can be assayed using HPLC to estimate the weight of theactive constituent of the drug in the specific dosage form.

In this work we used the HPLC techniques to estimate the exact amount of Metronidazole in samples, which are Metronidazole tablet 200 mg from differentpharmaceutical companies in Iraq pharmaceutical market to evaluate the content of drug in dosage form in these samples.The experimental work includes making calibration curve using standard solutions of different concentrations of the external standard metronidazole USP2002. Different readings of the area under the peak were obtained following the straight line equation.The result show that all of five samples are within maximum percentage of the differences allowed (95-105%) according to the B.P 2003.
Relationship between atenolol and early development of heart failure in hypertensive patients
Authors: Amin Enaam Ahmad , Hassan Suad Aziz , Ali Sarah TawfeekMohammed
Published: April 2022

Background:Atenolol is one of b–adrenergic receptor blocking agent, that is widely and commonly used in the treatment of hypertension, its lowering high blood pressure effectively but, it has many side effects on different body organs and tissues, some of them are serious.Objectives:To prove the association between Atenolol and heart failure through studying the effects of this drug on the levels of some parameters that are present in the blood including: total serum cholesterol, serum triglyceride and aspartate transaminase enzyme in early and long term usage of this drug by hypertensive patients, these parameters are chosen because they give an early indication about future development of cardiovascular disease.Methods:Case comparative study was conducted in Al-Yarmouk teaching hospital for one year and seven months on (40) hypertensive patients, they were dividedinto (2) groups according to the duration of the treatment:Group І: (20) patients with mean age (56 + 8) years .They used the drug for a period from (1-3) years.Group II: also (20) patients with mean age (55+ 8) years used the drug for (4- 10) years.Both groups were with the same number of sex and nearly the same age, venous blood samples are taken from each patients and levels of total serum cholesterol, serum triglyceride (S.TG), and Aspartate transaminase (AST) were estimated and compared between the (2) groups.Results:The mean of total serum cholesterol was significantly higher in group II than in group I (p<0.05) , the mean of S.TG was significantly higher in group II (p<0.05).Conclusion:Atenolol causes increase levels of total serum cholesterol, S.TG and AST and this increase is directly proportion to the duration of the drug usage and as they are affect on cardiovascular system and causing cardiovascular diseases by their high levels , so Atenolol has significant correlation with the developmentof cardiovascular diseases especially heart failure.
Effect of Silymarin against CAF protocol Hepatotoxicity
Authors: Mshemish Bahir Abdul Razzaq , Al-Khazragy Khalid Abdallaa , AL-Nakaash Munoor Abdul Ilah , Fatah Wiaam Abdul
Published: April 2022

Breast cancer became the commonest type of cancers among Iraqi women since the last two decades. The main underlying cause is thought to be DNAdamage; much of which is oxidative in nature. CAF protocol (Cyclophosphamide + Adriamycin + 5-FU) associated with toxic effects in several body organs (likeliver), mainly through production of free radicals and reactive oxygen species. Silymarin, the dried extract of a ripe seeds of the plant silybium marianum, wasfound to be a powerful antioxidant agent against toxin -induced tissue damage. Aim of the study is to evaluate the possible time and dose-dependent protective effect of the orally administered silymarin as antioxidant agent against oxidative stress-related hepatotoxicity induced by CAF protocol in breast cancer wome.Seventy four breast cancer women randomly distributed and allocated into three groups:Group (A): 24 patients received CAF protocol by I.V infusion once every 21 days and for 63 days.Group (B): 25 patients received 210mg/day of silymarin along with the same CAF protocol of group (A).Group (C): 25 patients received 420mg/day of silymarin along with the same CAF protocol of group (A).Indices of liver function (AST, ALT,TSB) were measured at baseline, after 21, 42, and 63 days of treatment.

The levels of AST and ALT, which were significantly elevated due to CAF protocol therapy, showed significant reduction when silymarin used with CAFprotocol, in a time and dose-dependent manner. Mean while, TSB levels significantly reduced by CAF protocol but dose not show any significant changeafter treatment with silymarin.Use of antioxidant agent (silymarin) in this study can ameliorate, in a time and dose-dependant manner, liver damage that induced by oxidative stress.Keywords: Breast cancer, CAF protocol (cyclophosphamide+Adriamycin+5- fluorouracil), hepatotoxicity, silymarin.
Analisis Pengendalian Kualitas Pada Crude Palm Oil untuk Meningkatkan Kualitas di PT. Condong Garut
Authors: Chandrahadinata Dody , Nurdiana Wakim
Published: April 2022

Tujuan dilakukannya penelitian ini adalah untuk Identifikasi faktor-faktor penyebab penyimpangan Kualitas dan memberikan usulan perbaikan produk CPO (Crude Palm Oil) pada PT Condong Garut. Metode penelitian ini menggunakan metode seven tools, FMEA dan Kaizen di untuk mengetahui bahwa penyimpangan kualitas produk terbesar terdapat pada kadar kotoran (55,56%) dan kadar air yang tinggi (38,27%). Faktor penyebab terjadinya kerusakan minyak kelapa sawit ini adalah faktor bahan baku, manusia, mesin dan metode kerja. Faktor kerusakan CPO yang paling berpengaruh diperoleh dengan melakukan analisis FMEA. Tiga RPN tertinggi yaitu pada penyebab kegagalan pada faktor mesin yaitu material serta ukuran ayakan (mesh) vibrating screen yang tidak sesuai dengan nilai 393, lalu diikuti oleh penyebab kegagalan  terdapat  kerusakan  pada  gear  drive  hydraulic  transmission pada vacuum dryer dan tidak adanya prosedur untuk mengoperasikan mesin vibrating screen dengan nilai RPN masing-masing sebesar 343 dan 240.Usulan perbaikan pada penelitian ini diberikan berdasarkan hasil cause and effect diagram dan RPN dengan menggunakan konsep kaizen berupa siklus PDCA (Plan Do Check Action) dan standarisasi.
Analisis Pengendalian Kualitas Printing Baju untuk Menurunkan Tingkat Kecacatan di CV. Huit Sportwear
Authors: Chandrahadinata Dody , Gemilang Clearen Amal Widya
Published: April 2022

Produk baju olahraga yang dihasilkan oleh CV. Huit Sportwear memiliki cacat produk pada proses printing yang berupa cacat hasil warna pudar, kertas kusut dan kertas robek. Tingkat kecacatan yang ditoleransi adalah 5% sedangkan pada prosesnya melebihi batas yang telah ditentukan sehingga perlu diperbaiki agar tingkat kecacatatannya dapat menurun. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor penyebab terjadinya cacat produk sehingga dapat menurunkan tingkat kecacatan pada proses printing dengan memberikan usulan perbaikan dengan cara mereduksikan kecacatan dari proses printing. Adapun pada penelitian ini menggunakan Six Sigma menggunakan 5 tahap antaralain Define, Measure, Analyse, Improve, dan Control (DMAIC). Berdasarkan hasil penelitian, terdapat beberapa faktor yang mempengaruhi tingkat kecacatan pada proses printing yaitu: mesin, material, manusia dan metode. Kaizen dilakukan untuk memberikan usulan perbaikan dan memfokuskan evaluasi dalam proses printing baju di Huit Sportwear. Dangan adanya penelitian ini, diharapkan dapat menyelesaikan permasalahan tersebut serta dapat menentukan usulan perbaikan sehingga bisa membantu pihak perusahaan untuk menurunkan tingkat cacat pada saat proses printing.
Perancangan Alat Bantu Pemotong Kerupuk untuk Meningkatkan Kapasitas Produksi UMKM Samawi
Authors: Oktaviani Shintya , Mauluddin Yusuf
Published: April 2022

Tujuan penelitian ini adalah untuk merancang alat pemotong adonan kerupuk untuk meningkatkan kapasitas produksi UMKM Samawi. Metode yang digunakan untuk penelitian ini adalah metode Nigel Cross atau metode rasional. Setelah desain direalisasikan dan  diimplementasikan pada produk UMKM mala terdapat beberapa temuan dalam penelitian ini diantaranya mesin pengerak beroperasi namun kecepatan putaran perlu dikurangi karena berpengaruh pada kualitas hasil potongan. Mata pisau dipasang pada piringan pisau dengan jumlah 2 buah, ketajaman mata pisau sangat baik dan dapat memotong adonan dengan baik.  Material kerangka utama terbuat dari besi siku 3cmx3cm, kerangka mesin cukup kuat untuk menopang namun ketika mesin dioperasikan kaki mesin tidak cukup kuat untuk meredam getaran yang dihasilkan mesin penggerak. Tersedia tempat untuk meletakkan adonan dan sudah berfungsi dengan baik. Ring plat setebal 1 mm  sudah dipasang, ketebalan hasil potong tidak seragam dan tidak rapi. Sehingga penulis merekomendasikan beberapa hal sebagai berikut: menggunakan mesin penggerak dengan kekuatan lebih besar, memasang pengatur kecepatan pada mesin dan mengolesi adonan yang akan dipotong menggunakan minyak goreng.
Analisis Kemampuan Pemahaman dan Pemecahan Masalah Matematis Siswa Kelas X Materi Persamaan Pertidaksamaan Nilai Mutlak
Authors: Nur Septia , Kartini Kartini
Published: April 2022

Penelitian ini bertujuan untuk menganalisis kemampuan pemahaman matematis dan kemampuan pemecahan masalah matematis siswa pada materi persamaan dan pertidaksamaan nilai mutlak. Subjek dalam penelitian ini adalah siswa kelas X SMA IT Imam Syafi’i Batam berjumlah 29 siswa. Teknik pengumpulan data yang digunakan adalah instrumen tes tertulis berbentuk uraian berjumlah 5 soal. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan deskriptif. Teknik analisis data yang digunakan dalam penelitian ini yaitu analisis inferensial untuk mengukur instrumen, serta analisis deskriptif untuk mengetahui kemampuan pemahaman matematis dan kemampuan pemecahan masalah matematis siswa. Berdasarkan hasil penelitian, dapat disimpulkan bahwa kemampuan pemahaman matematis yang dimiliki siswa siswa lebih baik dibanding kemampuan pemecahan masalah matematis. Rata-rata persentase kemampuan pemahaman matematis siswa kelas X untuk materi persamaan dan pertidaksamaan nilai mutlak adalah 90%, sedangkan rata-rata persentase kamampuan pemecahan masalah siswa hanya 28%. Selanjutnya, ditemukan pula hasil bahwa siswa kesulitan memahami soal permasalahan kontekstual, serta kesulitan menerapkan konsep persamaan dan pertidaksamaan nilai mutlak ke dalam prosedur penyelesaian masalah.
PENINGKATAN KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS SISWA MELALUI PEMBELAJARAN KOOPERATIF BERBASIS EDUCATION FOR SUSTAINABLE DEVELOPMENT
Authors: Putra Jaya Dwi , Suardi Didi , Juandi Dadang
Published: April 2022

Kemampuan pemahaman konsep matematis merupakan salah satu kemampuan yang penting bagi siswa dalam mencapai ketuntasan belajar matematika. Pemahaman yang baik akan suatu konsep sangat diperlukan dalam menyelesaikan suatu permasalahan matematika. Pentingnya pemahaman konsep matematis ini belum tercermin dari capaian hasil belajar matematika siswa. Berdasarkan data hasil tes yang diberikan masih banyak siswa yang kemampuan pemahaman konsep matematisnya rendah. Salah satu faktor penyebab masih rendahnya kemampaun pemahaman konsep matematis siswa adalah penerapan model pembelajaran yang tidak tepat. Disamping itu hal ini juga disebabkan kurangnya kebermaknaan dalam belajar yang dirasakan oleh siswa. Oleh karena itu sebagai solusi agar permasalahan tersebut dapat diatasi, diperlukan model pembelajaran yang dapat membuat pembelajaran lebih bermakna sehingga dapat meningkatkan pemahaman konsep matematis siswa. Pada penelitian ini dipilih pembelajaran kooperatif tipe jigsaw berbasis education for sustainable development. Penelitian ini bertujuan untuk menelaah perbedaan peningkatan pemahaman konsep matematis antara siswa yang memperoleh pembelajaran kooperatif tipe jigsaw berbasis education for sustainable development dan siswa yang memperoleh pembelajaran konvensional. Penelitian ini merupakan penelitian kuasi eksperimen dengan desain non-equivalent control group design. Populasi pada penelitian ini adalah siswa kelas XI pada salah satu SMA Negeri di Kecamatan Harau Provinsi Sumatera Barat. Sampel terdiri dari dua kelas yang dipilih secara purposive sampling. Instrumen yang digunakan tes kemampuan pemahaman konsep matematis. Berdasarkan analisis data disimpulkan bahwa bahwa peningkatan pemahaman konsep matematis siswa yang memperoleh pembelajaran kooperatif tipe jigsaw berbasis education for sustainable development lebih baik dibandingkan siswa yang memperoleh pembelajaran konvensional.
PENGEMBANGAN LEMBAR KERJA PESERTA DIDIK BERBASIS PROBLEM BASED LEARNING TERHADAP KEMAMPUAN BERPIKIR KREATIF MATEMATIS
Authors: Nurmala Rizka , Fikriani Tiara , Ayu Citra
Published: April 2022

Penelitian ini bertujuan untuk mengembangkan Lembar Kerja Peserta Didik (LKPD) matematika berbasis Problem Based Learning (PBL) untuk peserta didik kelas XI SMA. Pengembangan LKPD ini dilakukan untuk meningkatkan kemampuan berpikir kreatif matematis peserta didik. LKPD yang diberikan kepada peserta didik harus memenuhi kriteria validitas, praktikalitas, dan efektifitas. Penelitian ini menggunakan metodologi penelitian Research and Development (R & D) dengan model pengembangan 4D yang dimodifikasi. Dalam penelitian ini peneliti hanya melakukan 3 tahap yaitu define, design, dan develop. Tahap define dilakukan analisis kebutuhan, peserta didik, kurikulum dan materi. Tahap design dilakukan perancangan dan penyusunan materi pada LKPD berdasarkan analisis kebutuhan. Kemudian tahap develop dilakukan evaluasi sendiri yang selanjutnya divalidasi oleh para ahli, serta evaluasi perorangan terhadap 3 orang peserta didik dan evaluasi kelompok kecil oleh 6 orang peserta didik. Hasil penelitian menunjukkan bahwa LKPD berbasis PBL yang dikembangkan telah valid dengan nilai rata-rata validasi yaitu 81,5%. Nilai praktikalitas LKPD yang diperoleh dari angket respon peserta didik yaitu 86,6%. Berdasarkan nilai validitas dan nilai praktikalitas tersebut maka pembelajaran menggunakan LKPD berbasis PBL dapat meningkatkan kemampuan berpikir kreatif matematis peserta didik.
PENGARUH MODEL PEMBELAJARAN LAPS-HEURISTIK DENGAN TIME TOKEN ARENDS TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIS
Authors: Ali Mailan , Netriwati Netriwati , Dewi Novian Riskiana
Published: April 2022

Keterampilan penting yang seharusnya dikuasai peserta didik adalah keterampilan menyelesaikan permasalahan. Kurang beragamnya model selama pembelajaran membuat pembelajaran menjadi monoton dan membosankan. Hal ini menjadi kendala dalam menumbuhkan kemampuan pemecahan masalah pada peserta didik. Penelitian ini bertujuan untuk melihat perbedaan kemampuan pemecahan masalah antara peserta didik yang diterapkan model LAPS-Heuristik dengan Time Token Arends (TTA) dan peserta didik yang diterapkan model konvensional. Penelitian ini adalah kuantitatif menggunakan metode Quasy Experimental Design dengan rancangan Post-test Only Control Group. Populasi penelitian ini adalah peserta didik tingkat dua di MTs Daarul Maarif Natar dan dengan sampel kelas VIII A menjadi kelas percobaan dan kelas VIII B menjadi kelas kontrol. Teknik pengumpulan data menggunakan soal berbentuk uraian untuk mengukur kemampuan pemecahan masalah peserta didik. Uji hipotesis yang digunakan yaitu uji-t. Berdasarkan hasil pengujian hipotesis terdapat perbedaan pengaruh antara peserta didik dengan penerapan model LAPS-Heuristik dengan TTA dan penerapan model konvensional. Dengan Effect Size sebesar 0,59 berarti bahwa model LAPS-Heuristik dengan TTA memberikan andil yang sedang terhadap kemampuan pemecahan masalah peserta didik.
PENERAPAN STRATEGI KONFLIK KOGNITIF DENGAN TEKNIK THINK-PAIR-SHARE UNTUK MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA
Authors: Putri Handayani Eka , Adiputra Yosi
Published: April 2022

Abstrak

Penelitian ini dilatarbelakangi oleh rendahnya kemampuan pemecahan masalah matematis pada materi geometri di Sekolah Menengah Atas. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan peningkatan kemampuan pemecahan masalah matematis siswa SMA yang pembelajarannya menggunakan strategi konflik kognitif dengan teknik think-pair-share dibandingkan dengan pembelajaran konvensional. Penelitian ini merupakan penelitian kuasi eksperimen. Desain penelitian yang digunakan yaitu Nonequivalent Pre-test Post-test Control Group Design dan teknik pengambilan sampelnya adalah Purposive Sampling. Populasi dalam penelitian ini adalah siswa kelas XII SMA Binaul Ummah Kuningan tahun pelajaran 2021/2022. Sampel penelitian ini terdiri atas 2 kelompok yaitu kelompok Eksperimen berjumlah 28 siswa dan kelompok kontrol berjumlah 23 siswa. Instrumen yang digunakan berupa tes kemampuan pemecahan masalah matematis. Analisis data dilakukan secara kuantitatif dengan menggunakan uji Mann-Whitney. Hasil penelitian menunjukkan bahwa peningkatan kemampuan pemecahan masalah matematis siswa yang pembelajarannya menggunakan strategi konflik kognitif dengan teknik think-pair-share lebih baik dibandingkan dengan siswa yang mendapatkan pembelajaran konvensional.

Kata Kunci : Konflik Kognitif, think-pair-share, pemecahan masalah
Penerapan Model Creative Problem Solving Terintegrasi Nilai Islam untuk Meningkatkan Kemampuan Berpikir Kreatif Matematis
Authors: Sartika Nenden Suciyati , Yulita S Susti Rahmah , Laeliyah Siti
Published: April 2022

Penelitian ini bertujuan untuk mengetahui ada atau tidaknya peningkatan kemampuan berpikir kreatif matematis siswa yang menggunakan model pembelajaran Creative Problem Solving (CPS). Penelitian ini merupakan penelitian quasi eksperiment. Populasi dalam penelitian ini adalah siswa MTs Darussa’adah Cikadueun dan sampel penelitian ini adalah kelas VIIIA yang berjumlah 21 orang (sebagai kelas kontrol) dan kelas VIIIB yang berjumlah 21 orang (sebagai kelas eksperimen). Berdasarkan hasil analisis dapat diambil kesimpulan bahwa terdapat peningkatan kemampuan berpikir kreatif matematika siswa antara yang menggunakan model pembelajaran CPS dan pembelajaran konvensional. Ini terlihat dari mean ketuntasan hasil belajar dengan model CPS sebesar 77,90 lebih baik dari hasil belajar dengan pembelajaran konvensional sebesar 70,66, dan peningkatan dapat dilihat dari uji t tes N-gain yaitu sebesar 9,88. Dengan demikian dapat disimpulkan bahwa terdapat peningkatan yang positif bila menggunakan model CPS terhadap kemampuan berpikir kreatif matematis siswa MTs Darusa’adah Cikadueun.Kata Kunci: Creative Problem Solving, Kemampuan Berpikir Kreatif Matematis Siswa
Integração Estratégica à Projetos de P&D: estudo de caso de multinacional francesa do setor energético
Authors: Rosa Marcelo Scorsato de
Published: April 2022

A empresa que busca competitividade no mercado em que atua e em futuros mercados tem como um dos fatores de competitividade as suas tecnologias estratégicas. Entretanto, para que surta o efeito esperado é importante que os projetos desenvolvidos por P&D tenham aderência como o planejamento estratégia da empresa à fim de maximizar os resultados. O objetivo desse artigo é avaliar a aderência entre os projetos desenvolvidos em P&D e o planejamento estratégico. Nesse estudo a pesquisa realizada tem caráter exploratório de natureza qualitativa e os dados foram coletados por meio de entrevistas semiestruturadas e questionários. Como resultado da pesquisa, apontou-se os pontos fracos e fortes da empresa conforme afirmação dos funcionários em relação a aderência dos projetos de P&D e o planejamento estratégico. Observou-se também a concordância dos participantes quanto a importância do alinhamento da estratégia da empresa e P&D.
Condutas no descolamento prematuro de placenta
Authors: Souza Girlete Silva de , Oliveira Silvânia Pires de , Moraes Daniel Silva , Alves Ana Paula de Oliveira Nacimento , Soares Davidson Gonçalves , Martins Luana Oliveira , Silva Neuriene Queiroz da , Alencar Ana Maria , Peres Jessica Fernanda Silva , Scremin Marlete , Monteiro Sylmara Corrêa , Amaral Bruno de Pinho , Silva Karla Talita Santos , Cordeiro Flabiane Carvalho , Carvalho Thamires Dias de
Published: April 2022

Introdução: O descolamento prematuro da placenta é considerado como urgência obstétrica com elevado potencial de morbimortalidade materna e fetal. Objetivo: Analisar as práticas de assistência à gestante com descolamento prematuro da placenta. Metodologia: Trata-se de um estudo de revisão integrativa da literatura, definiram-se como fonte de busca as bases de dados eletrônicas Lilacs, BDENF, Scielo e PUBMED que são consideradas como referências na produção científica na área da saúde. Resultados: A gestante com descolamento prematuro da placenta exige uma identificação rápida e efetiva do diagnóstico, o que ajuda no manuseio e na solução de prováveis adversidades. Dessa forma, o trabalho da equipe multidisciplinar é essencial na assistência a gestante para a conquista de melhores resultados materno e neonatal. Conclusão: As condutas para o descolamento prematuro de placenta abordam como aspectos fundamentais, dentre eles: a propedêutica clínica e obstétrica. O tratamento dependerá do grau do descolamento (Grau 1, 2 ou 3) que se reflete no estado hemodinâmico materno e da vitalidade fetal.
Microscopic analysis of the repair of critical bone defects in rabbits calvaria after the use of particulated autogenous bone or particulate autogenous bone associated with inorganic biomaterial
Authors: André Sérgio Borlot , Tavares Paulo Matheus Honda , Silva Maísa Pereira da , Jesus Laís Kawamata de , Hadad Henrique , Bizelli Vinicíus Ferreira , Ponzoni Daniela , Bassi Ana Paula Farnezi , Souza Francisley Ávila , Carvalho Paulo Sérgio Perri de
Published: April 2022

The aim of this study was to evaluate, through microscopic analysis, the repair of critical defects in rabbit calvaria after the use of particulate autogenous bone or particulate autogenous bone associated with inorganic biomaterial. Six male albino rabbits, New Zealand, were used, in which 4 defects were performed in each calvaria and randomly divided into 4 equitable groups: Group I – performed bone defect; Group II – performed bone defect and filled with particulate autogenous bone; Group III – performed bone defect and filled with particulate inorganic material (Bio-Oss®, Geistlich from Brazil); Group IV – performed bone defect and filled with particulate autogenous bone associated with particulate inorganic material (Bio-Oss® - Geistlich from Brazil) with proportion being 20:80. The analyze time of the procedure was 60 days. The microscopic analyze allowed to conclude that the autogenous, the Bio-Oss® and the Bio-Oss® associated with autogenous bone groups showed a bone neoformation on the defects, characterizing the material osteoconductive. However, the complete defect closure occurred on the autogenous bone and the autogenous bone associated with the inorganic bone, showing that the presence of the autogenous bone improves the characteristics of the biomaterial. The use of inorganic bone associated with the autogenous bone allowed a complete bone neoformation of the critic defect in the calvaria of rabbits.
Atividades lúdicas para realizar com bebês de 8 meses a dois anos de idade
Authors: Mello Bruna Leticia Cagalli de , Braga Francisco Carneiro , Guimaraes Junior José Carlos , Oliveira Fernando Augusto de Lima , Vitorino Anderson Francisco , Ribeiro Valquíria Ferreira , Marques Janaína Arruda , Paz Charle Ferreira
Published: April 2022

Neste objetivou-se a identificação das atividades lúdicas para desenvolver com os bebês  de 8 meses a dois anos de idade- fazendo usos de brincadeiras, brinquedos e materiais do nosso dia– a dia, buscando o desenvolvimento da aprendizagem dos bebês e das crianças desde muito novos. Utilizou-se como métodos de pesquisa, a revisão de literatura com os seguintes assuntos: brincadeiras e brinquedos  para os bebês, o brincar no berçário, atividades para berçário 1 e 2, atividades para berçário 1 e 2, atividades lúdicas e educativas, dentre outros. Através da realização dessa pesquisa conclui-se que: as brincadeiras, os brinquedos e desenvolvem um trabalho mais voltado a ludicidade o bebê ou a criança consegue se desenvolver melhor, aprende melhor as coisas, aguça a curiosidade, a imaginação, aprimora os movimentos, a coordenação motora, a destreza, ou seja, tudo da maneira mais divertida e muito mais prazerosa.
Vivência e experiência no estágio supervisionado em ensino de Geografia II no contexto pandêmico
Authors: Lima Jhonatas Isac Pereira , Santos Luiz Claudio Correia dos , Alves Alessandra Conceição Monteiro , Ferro Marcos Batinga
Published: April 2022

O presente texto descreve as experiências desenvolvidas no Estágio Supervisionado em Ensino de Geografia II que é um componente curricular obrigatório para todos os alunos do curso de Geografia da Universidade Federal de Sergipe. O estágio foi realizado na Escola Estadual General Calazans, localizada no município de Nossa Senhora das Dores-SE em 2021. Devido, ao momento pandêmico as atividades ocorrem de forma síncrona e assíncrona. O estágio teve 2 meses de regência com total de 12 horas/aula. A primeira semana foi apenas apresentação dos estagiários e observação tanto do professor regente e alunos presentes, já na segunda semana foi necessário auxiliar o professor com o conteúdo e atividades. Por fim, a segunda etapa teve 6 semanas de regência, porém divido 3 semanas para cada dupla. Percebe-se que o estágio traz uma aproximação dos licenciados com a realidade educacional, pois, proporcionando experiências diversas, onde tais alunos poderão compreender os desafios e a importância de sua profissão para uma sociedade mais justa.
Aspectos botânicos, fitoquímicos e antimicrobianos da Matricaria chamomilla L. (Asteraceae): uma breve revisão
Authors: Souza Lara Danúbia Galvão de , Farias João Henrique Anizio de , Rodrigues Ana Caroline , Alencar Aléxia Araújo , Medeiros Jessika Paiva , Alencar Josilanny Araújo de Souza , Medeiros Maria Alice Araújo de , Alves Millena de Souza , Anjos Raline Mendonça dos , Oliveira Filho Abrahão Alves de
Published: April 2022

Objetivo: O presente trabalho consiste em uma revisão de literatura acerca da Matricaria chamomilla, destacando seus aspectos botânicos, fitoquímicos e atividades farmacológicas, em especial antibacterianas. Metodologia: Foi realizada uma revisão narrativa da literatura. As bases de dados utilizadas foram: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), BVS – Biblioteca Virtual em Saúde, biblioteca eletrônica Scientific Electronic Library Online (SciELO) e Google acadêmico. Os critérios de inclusão foram: pesquisas cujo objetivo fosse o uso fitoterápico da Matricaria chamomilla, publicadas em inglês, português ou espanhol; em formato de artigos, revisões, dissertações e teses no período de 2015 a 2021. Os materiais que foram relevantes e atenderam aos critérios de inclusão foram selecionados e analisados. Em seguida realizou-se o agrupamento e síntese das temáticas, apresentando o conhecimento de forma detalhada sobre o tema proposto. Resultados: A Camomila possui um grande potencial biológico, esse ocorre em função da existência de vários grupos de substâncias ativas. Acerca desses componentes fitoquímicos da Matricaria chamomilla, destacam-se os terpenos, sendo exemplos o camazuleno e o bisabolol, responsáveis pela atividade anti-inflamatória e antiproliferativa.  Sobre a atividade antibacteriana, estudos relevam que essa se torna maior quando há a associação de antibiótico com o óleo essencial. Conclusão: A partir do levantamento bibliográfico da Matricaria chamomilla pode-se reforçar a relevância de seu uso medicinal nas mais variadas formas farmacêuticas, principalmente como agente antibacteriano natural.
Avaliação de microrganismos psicotrópicos ao longo das etapas de produção, coleta e transporte do leite cru resfriado
Authors: Strassburger Alexandre Henrique , Thaler Neto André , Mendes Rose Maria de Oliveira , Marafon Fernanda , Costella Marcelo Fabiano , Lajús Cristiano Reschke , Mello Josiane Maria Muneron , Onofre Sideney Becker , Dalcanton Francieli
Published: April 2022

O objetivo deste estudo foi avaliar a contagem dos microrganismos psicrotróficos (MP), composição do leite e contagem padrão em placa (CPP) e contagem de células somáticas (CCS) nos elos de produção, iniciando pela propriedade rural até a chegada do leite à indústria. Foram selecionados 55 produtores para a coleta do leite, divididos em quatro rotas da região sudoeste do Rio Grande do Sul destinado à indústria beneficiadora em SC. Aplicou-se formulário nos produtores para avaliar as condições de estrutura e higiene no manejo de ordenha e obtenção do leite. Nos resultados, o item de higiene das instalações apresentou pior resultado para a contagem de psicrotróficos. Os resultados das amostras ao longo de toda cadeia para contagem de psicrotróficos e Contagem Padrão em Placas nas etapas acompanhadas apresentaram variação de 1,5 log10UFC/mL e 0,6 log10UFC/mL, respectivamente. Mesmo com aumento da contagem de psicrotróficos e CPP ao longo das etapas não houve alteração na composição do leite que foi entregue a indústria processadora. É necessário o acompanhamento dos microrganismos psicrotróficos ao longo de todas as etapas e no futuro a definição de padrões para que a atividade leiteira defina ações para a redução e controle desse microrganismo.
Effects of ozone therapy in an experimental murine model of Candida albicans vulvovaginitis
Authors: Pilatti Cleverson Marcelo , Franzes Dayane Batista , Rangel Drauzio Eduardo Naretto , Loth Eduardo Alexandre , Genske Rodrigo Daniel , Cecatto Vanessa , Pessoa Rodrigo Sávio
Published: April 2022

The antifungals used in the treatment of vulvovaginal candidiasis, although effective, can have side effects and high cost, which may not occur with the medicinal use of ozone. The study aimed to evaluate the effects of medicinal home ozone therapy on C. albicans. The experiment was carried out in vitro, cultivating C. albicans in 10mm Petri dishes, containing solid Agar Sabour and Dextrose (Oxoid). The in vivo experiment used 45-day-old female C57/BL6 mice and after suppression of ovarian activity, 20 µL of C. albicans suspension in sterile PBS, at a concentration of 105 yeast cells, were inoculated in a single dose under anesthesia. Distribution occurred in 4 groups: (i) Absolute Control Group (GCA): Not subjected to infection by the pathogen. (ii) Control Group (CG): Submitted to C. albicans infection, but not treated. (iii) Ozone Therapy Group (GO): Subjected to infection and treated with medicinal ozone therapy. (iv) Lavage Group (GL): Subjected to infection and subsequently treated with vaginal lavage. It was found that GC had a higher amount of CFU when compared to GO. Exposure for 600s was able to reduce the number of CFUs by 98.89% when compared to GC. The study concludes that ozone gas showed great efficacy in the proliferation of C. albicans in vitro. The best results were observed with application in liquid medium, however, ozone therapy was able to significantly reduce infection in the experimental model used. In in vivo experiments, the number of CFU/ml found was lower in the ozone-treated group.
Queixas musculoesqueléticas e nível de estresse relacionados aos hábitos de vida de universitários durante a pandemia
Authors: Oliveira Sabrina Marques de , Santos Stefany Oliveira dos , Gouveia Samara Sousa Vasconcelos
Published: April 2022

Objetivo: Investigar as queixas musculoesqueléticas e o nível de estresse em universitários relacionados aos hábitos de vida durante a pandemia. Metodologia: Este projeto trata-se de um estudo quantitativo transversal, através de uma pesquisa de campo. Foram convidados a participar acadêmicos dos cursos de Fisioterapia, Medicina, Biomedicina, Psicologia, Biologia, Ciências Contábeis, Ciências Econômicas, Engenharia de Pesca, Administração, Matemática, Pedagogia e Turismo da Universidade Federal do Delta do Parnaíba, que tivessem idade entre 18 e 45 anos e que aderiram ao ensino remoto, aqueles que não responderam a todos os questionamentos e/ou que desistiram da pesquisa foram excluídos. A pesquisa deu-se por meio da aplicação de questionários virtuais, enviados via SIGAA para todos os discentes. Resultados: Participaram da pesquisa 116 universitários, 90,5% desses referiu ter apresentado comprometimento em pelo menos uma região, onde os locais mais acometidos foram a parte superior e inferior das costas (61,2%), punhos/mãos (52,6%) e pescoço (49,1%), sendo a maior predominância das dores no gênero feminino. Foi constatado, ainda, que as mulheres apresentam um maior nível de estresse (25,1 (±6,26)). E, quando comparado o estresse com o sono, foi percebido que aqueles que tinham sono ruim ou muito ruim apresentaram uma pontuação superior (26,9 (±6,3)). Conclusão: Foi identificado um elevado número de queixas musculoesqueléticas, principalmente entre indivíduos do sexo feminino. Além disso, o estresse também foi considerado um outro problema bastante comum entre os estudantes, em especial nas mulheres e naqueles que apresentam um sono ruim.
Percepções da humanização na atuação profissional de psicólogas em um hospital escola
Authors: Mendes Matheus Carvalho , Valeri Beatriz Oliveira
Published: April 2022

Levando em consideração como o profissional da Psicologia concebe o indivíduo e como as diretrizes e os princípios da política de humanização direcionam o cuidado, percebe-se uma aproximação entre o psicólogo e o construto da humanização. Sendo assim, torna-se imprescindível compreender como esse profissional, tão importante para que haja a implementação da prática dessa política, compreende o significado de humanização e como visualiza, em seu cotidiano, sua prática em consonância a esse construto. Objetiva-se acessar a compreensão de profissionais da Psicologia sobre o conceito de humanização, além de analisar em que medida as condutas humanizadas contemplam sua compreensão do conceito, bem como identificar os aspectos que favorecem ou não tal prática. Trata-se de uma pesquisa transversal, descritiva e qualitativa, possuindo como método a análise de conteúdo, a partir das respostas a uma entrevista elaborada para contemplar os objetivos estudo. Foi possível compreender que as profissionais de Psicologia possuem amplo conhecimento sobre a concepção de humanização. Observou-se que este conhecimento vai muito além do que conseguem implementar na prática profissional. Tal prática encontra diversos dificultadores para atingir um caráter idealmente humanizado, uma vez que se mostraram resistentes, atravessando o cotidiano da assistência. Foram identificados menor quantidade de facilitadores quando comparados aos dificultadores. Todavia, tais facilitadores mostraram-se ser um suporte relevante para que as profissionais tentem, no seu cotidiano, superar os desafios para realização de uma assistência humanizada e de qualidade.
Assistência de enfermagem ao câncer renal: um relato de experiência
Authors: Santos Kelly Teixeira , Nunes Larissa Giordana , Panzetti Tatiana Menezes Noronha
Published: April 2022

Objetivo: Descrever a assistência de enfermagem prestada ao câncer renal e suas complicações pós-operatórias. Metodologia: Trata-se de um estudo descritivo, do tipo relato de experiência que foi desenvolvido nos dias 09 a 24 de agosto de 2021, na clínica de urologia de um hospital referência em oncologia no Estado do Pará, referente a assistência de enfermagem em acometidos pelo câncer renal que evoluíram com complicações pós-operatórias. Resultados e discussão: O desenvolvimento da experiência ocorreu no período de pós-operatório e a partir da evolução do quadro clínico da doença foi elaborado um plano de cuidados voltado para as possíveis complicações pós-operatórias em nefrectomia. Os diagnósticos foram elaborados com base na Taxonomia II da NANDA-I, na versão 2018-2020 e as intervenções propostas com base na Classificação das Intervenções de Enfermagem – NIC versão 2016. Conclusão: A assistência de enfermagem oncológica requer cuidados baseados em habilidades técnicas e conhecimentos científicos, principalmente diante de possíveis complicações envolvendo aspectos físicos, fisiológicos, psicológicos, sociais e espirituais. Nesse sentido é imprescindível que a equipe de enfermagem disponha de aptidões para promover uma assistência de qualidade, humanizada e holística, visando reduzir os efeitos adversos do tratamento.
Produtividade e indução de enzinas antioxidantes em Feijão-caupi (Vigna unguiculata) irrigado com água salina e Inoculado com Bradyrhizobium
Authors: Souza Luana de Pádua , Santos Carolina Etienne de Rosália e Silva , Simões Adriano Nascimento , Aviz Rhaiana Oliveira de , Silva Nágila Sabrina Guedes da , Freitas Ana Dolores Santiago de , Stamford Newton Pereira , Silva Vinícius Santos Gomes da
Published: April 2022

Acredita-se que a associação de bactérias fixadoras de nitrogênio minimize os efeitos adversos causados por estresses ambientais em feijão-caupi cultivado no semiárido, dessa forma, objetivou-se avaliar as respostas de diferentes genótipos de feijão-caupi inoculados com estirpes recomendadas, irrigados com diferentes lâminas de água salina. O experimento foi desenvolvido na Unidade Acadêmica de Serra Talhada (UFRPE/UAST). Utilizou-se delineamento em blocos casualizados, em parcelas subsubdivididas (4 x 2 x 3), cujos tratamentos foram diferentes lâminas de irrigação (25, 50, 75 e 100 % da evapotranspiração da cultura - ETc), associado a dois genótipos de feijão-caupi (IPA 206 (G1) e BRSTumucumaque (G2), além de dois inoculantes (BR 3262 (I1) e BR 3267 (I2) e tratamento sem inoculação. As lâminas de irrigação com sua máxima aplicação (100%), proporcionaram um maior acúmulo de fitomassa. Em relação a nodulação, a lâmina de 25% foi a mais indicada. O genótipo G1 proporcionou produtividade de 1,95 t ha-1 e o G2 2,12 t ha-1 médias muito superior a Nacional, que é em torno de 400 kg ha–1. A atividade da enzima Polifenoloxidase (PPO) foi aumentada com a lâmina de 100% no G2, independente do inoculante e da lâmina utilizada. A atividade da e Peroxidase (POD), foi maior com 100% de água de irrigação em relação as condições de 25%, para os dois genótipos. O genótipo G2 apresentou mais compostos fenólicos em relação ao G1, nas condições de lâmina máxima (100%), quando comparando-se o teor de compostos fenólicos, que pode ser uma resposta ao estresse hídrico e salino.