bluuebunny/crossref_metadata_2025 huggingface dataset:
Pharmacokinetic parameters of Tilmicosin Phosphate in the body of healthy broiler chickens
Authors: Dukhnitsky V. , Sokolyuk V. , Tishkovskaya A. , Tishkovskiy M. , Ligomina I.
Published: January 2022

The article presents the results of studies of the intake (oral administration), distribution and excretion of Tilmicosin Phosphate (active ingredient of the Tilmox 25%) from the body of healthy broiler chickens of the KOBB-500 cross. The rapid absorption of Tilmicosin Phosphate from the alimentary tract of the birds and its entry into the internal organs was established. The maximum content of Tilmicosin Phosphate was found in the lungs and liver. Only in 2 hours after the beginning of the Tilmox 25% solution application, which was 17.02 ± 0.24 and 12.78 ± 0.22 μg / g, its content in the kidneys after 26 hours was 8 25 ± 0.19 μg / g, pectoral and cardiac muscles after 52 hours - 6.19 ± 0.28 and 5.23 ± 0.39 μg / g, respectively. Consumption of Tilmox 25% solution by a healthy bird was not accompanied by the accumulation of Tilmicosin Phosphate (material accumulation), since its content in the internal organs and muscles of the bird did not depend on the duration of the drug use. During 96 hours of Tilmox 25% solution consumption by broiler chickens the maximum content of Tilmicosin Phosphate was detected in the lungs, which indicates its tissue tropism. The distribution of Tilmicosin Phosphate in maximum amounts to the lungs ("organ affinity" or "tissue tropism") is important when infectious agents are localization in the lungs of poultry, as well as for the treatment of patients with respiratory diseases of various etiology. The cessation of the use of Tilmox 25% was accompanied by a significant decrease in the content of its active substance, Tilmicosin Phosphate, in the organs under study. Twenty-four hours after the cessation of consumption the tilmox solution (120 hours of the experiment), the content of Tilmicosin Phosphate in the lungs was 1.9 times less, liver – 1.6 times, kidneys – 1.4 times, pectoral muscle - 1.7 times, cardiac muscle – 1.3 times less, compared with indicators on 96 hours of experiment. Five days after the cessation of feeding the tilmox solution to broiler chickens (216 hours of the experiment), the residual amounts of Tilmicosin Phosphate in the organs under study were: in the lungs – 1.20 ± 0.03 μg / g; liver – 1.01 ± 0.02; kidneys - 0.91 ± 0.03 μg / g. The lowest content of Tilmicosin Phosphate, during this period of research, was only in one of the three samples of the heart muscle – 0.02 μg / g, and it was not detected in the pectoral muscle.
Key words: Tilmox 25 %, organs, distribution, accumulation, excretion, pharmacokinetics.
Serological monitoring of brucellosis among wild boars in Ukraine during 2019–2020
Authors: Aliekseieva H. , Pyskun A. , Piankivska I. , Polishchuk O. , Mietolapova H.
Published: January 2022

The key to the successful development of animalhusbandry is the epizootic welfare of the country. Forimplementation the set of preventive measures it is requiresa perfect system for diagnosing infectious diseases, includingbrucellosis. Despite the fact that Ukraine is consideredofficially free from this zoonosis among farm animals, thesituation regarding it in the wild fauna of our country remainsinsufficiently studied.This article presents the results of serological studies of548 sera samples of wild boars from 16 regions of Ukraine,collected during 2019 – 2020. The research was conductedon the basis of the State Scientific and Research Institute ofLaboratory Diagnostics and Veterinary and Sanitary Expertise(SSRILDVSE, Kyiv, Ukraine) by using the complementfixation test (CFT) and enzyme-linked immunosorbent assay(ELISA). In addition, all positive samples were further testedon yersiniosis with differential purposes.The systematization of obtained results show thatantibodies to Brucella spp. in sera samples from wild boarsin Ukraine were detected by CFT in 57 samples (10.4 % ofthe total number), by ELISA – in 83 (15.1 %). In general,antibodies to these pathogens were diagnosed in samplesfrom 13 regions (most often from Zhytomyr, Lviv andChernihiv).Positive samples by CFT and/or ELISA werefurther tested for the presence of antibodies to Yersiniaenterocolitica because, according to the literature andguidelines for diagnostic kits, possibility of crossreactions between brucellosis and yersiniosis. As a resultof differential studies, from the 83 positive on brucellosissamples, 42 also showed antibodies to Y. enterocolitica.Taking into account the cross-reactions between tests forbrucellosis and yersiniosis, antibodies to Brucella spp.during the analyzed period were found in 7.5 % of animals(in 41 of 548 samples).The prospect of this work is to further studies of theepizootic situation regarding brucellosis in the wild faunaof Ukraine. The obtained results indicate the circulationof antibodies to this zoonosis among wild boars in ourcountry.
Key words: Brucella spp., Yersinia enterocolitica,zoonosis, serological studies, CFT, ELISA, wild fauna.
Determination of the drug Fagomast effectiveness with different titers of Phage SAvB14
Authors: Horiuk Y.
Published: January 2022

Treatment of bacterial infections with bacteriophages is one of the alternative methods. However, the use of freely dispersed bacteriophages for treatment causes their inactivation under physiological conditions. Therefore, it is important to consider the concentration of bacteriophages in phage therapy. The aim of study – to determine the optimal titer of bacteriophage Phage SAvB14 in the drug Fagomast for the effective treatment of subclinical mastitis in cows caused by Stapholococcus aureus var. bovis. For research to determine the optimal therapeutic dose of the bacteriophage drug Fagomast in vitro, groups of animals were formed on the principle of analogues. Controls were animals treated with an antibiotic-based drug according to the instructions for use. Cows of the first experimental group were used samples of the drug with a titer of Phage SAvB14 10-7 BFU/ml, the second experimental group with a titer of 10-8 BFU/ml and the third group – 10-9 BFU/ml. It was found that all batches of Fagomast (81.8 - 92.8%) show good therapeutic efficacy, but the duration of treatment of animals was different. When using the drug Fagomast with a phage titer of 10-9 BFU/ml, it is shorter by 1 day than cows that were injected with a phage titer of 10-8 BFU/ml and 1.5 days compared with cows of the first group, which were injected with a phage titer of 10-7 BFU/ml. The results of the therapeutic efficacy of Fagomast with a bacteriophage titer of 10-8 and 10-9 BFU/ml in the drug are confirmed by the reaction with Mastidine, which after 48 hours was assessed as doubtful, and after 72 hours – as negative, as with antibiotic treatment. The content of S. aureus in the secretion of cows 12 hours after administration of the drug with a phage titer of 10-9 BFU/ml decreased 6 times (P ≤ 0.05), and after 48 hours 40 times (P ≤ 0.05), and after 60 hours of therapy did not stand out at all. The titer of bacteriophages remained at the level of 10-7 BFU/ml, and when the number of susceptible bacteria decreased to zero it decreased by 2 orders of magnitude. Thus, it can be said that maintaining a higher concentration of phage virions leads to better distribution of phages in the breast, and thus to improved binding of phages to host cells and their destruction.
Key words: bacteriophages, Staphylococcus aureus, phagotherapy, bacteriophage drug, mastitis, cows.
Predicting the course of the postpartum period in cows
Authors: Skliarov P. , Zubkov O.
Published: January 2022

The postpartum period plays a crucial role in restoring reproductive function and, consequently, the milk productivity of cows. Its importance lies in the fact that it marks the transition from pregnancy and birth to lactation and preparation for new fruiting. The course of puerperium depends on the condition of the mother's body, the course of pregnancy and childbirth, feeding conditions, maintenance, care and operation. In this regard, the aim of the work was to develop a program for predicting the course of the postpartum period in cows. The development of the program for predicting the course of the postpartum period in cows was carried out with the participation and advice of employees of the Department of Veterinary Reproductology of Kharkiv State Zooveterinary Academy on the basis of "Peremoha AVK" MVC "Ekaterinoslavsky" Dnipro district of Dnipropetrovsk region. The study is conducted in the late dry period (last 2-3 weeks of pregnancy). Obtained by the results of clinical, laboratory (morphological and biochemical) and special (sonographic) studies, the evaluation parameters were part of the algorithm developed on the principle of database management system in MS Exel program – indicators for assessing the clinical condition of the animal, homeostasis, completeness of feeding and activity movement of the cow, the condition of her breast and fetoplacental complex (fetal weight, placental size, diameter of the middle uterine artery) and colpocytograms. Each indicator corresponds to two variants of objective values with their own scale. The conclusion is determined by the sum of points for all items of the program. To do this, you only need to enter certain information into the program that determines one or another option: the sum of scores 51- 100 indicates a low probability of pathological processes, less than 50 – high. The use of the program itself makes it possible to obtain objective information and timely take appropriate measures to prevent the occurrence and development of pathological processes, maintaining the health and life of women in labor.
Key words: cattle, puerperium, reproductive function, forecasting programs.
Pharmacotherapy of knemidocoptosis in budgerigars
Authors: Kozii N. , Shahanenko V. , Shahanenko R. , Rublenko S. , Avramenko N.
Published: January 2022

The article presents a study of the pharmacotherapeutic efficacy of drugs of etiotropic action Ivermikol drops and Aversectin ointment for cnemidocoptosis in budgerigars. Treatment was directed to the study of etiotropic therapy of acaricidal drugs in relation to the causative agents of invasion in sick birds and in the environment. Extensibility and intensity (EE and IE) of the drugs were assessed on the 6th, 22nd and 36th days after the treatment. A study group of budgies suffering from knemidocoptosis was given the following treatment regimen: ivermicol drops, chlorhexidine and Perlen multivitamized grain mixture for food. According to the treatment, on the 6th day in budgies, the extensibility was 0 %. On the 22nd day of treatment in 4 parrots during microscopic examination of scrapings from the affected areas, Knemidocoptes mites were found. Thus, the extensibility of ivermicol drops was 33.3 %. On the 36th day, the extensibility of the treatment of parrots with ivermicol drops was 100 %. Thus, the results obtained make it possible to recommend the indicated scheme for the treatment of ornamental birds for knemidocoptosis. Thuse of the treatment of sick budgerigars according to a different scheme (aversectin ointment, chlorhexidine and multivitamized Perlen grain mixture for nutrition) also proved to be effective. However, on the 22nd day of treatment, microscopic examination of scrapings from the affected areas revealed Knemidokoptes mites in 5 parrots, thus, the extensibility of aversectin ointment was 16.7 %. On the 36th day of treatment in parrots of the control group, which were treated with aversectin ointment, the EE of treatment was 66 %, since 2 out of 6 parrots remained sick, which required further treatment. The dynamics of the EE and IE of ivermicol drops and avesectin ointments on the 6th, 22nd, and 36th days of the study indicate the highest therapeutic efficacy of ivermicol drops. Thus, the use of ivermicol drops as a means of etiotropic action in the cinemidocoptosis of budgerigars is effective.
Key words: scabies, treatment, knemidocoptosis, parrots, Cnemidocoptes pilae, acaricidalpreparations, ivermicoldrops, aversectinointment.
Diagnosis of leprosy by PCR targeting gene encoding 36 kDa antigen of Mycobacterium leprae
Authors: Shampa Shaira Akter , Roy Chandon Kumar , Begam Mahfuja , Farzana Aleya , Hossain Kazi Manwar , Anwar Shaheda , Saleh Ahmed Abu
Published: January 2022

Background & Objective: This cross sectional study was carried out to assess the diagnostic value of PCR in different forms of leprosy. For the detection of Mycobacterium leprae, DNA amplification by polymerase chain reaction of a 531-bp fragment of the Mycobacterium leprae specific gene encoding the 36 kDA antigen.

Methodology: It was done on different clinical specimens (slit smear of skin, ear lobule smear and nasal smear) from 50 leprosy patients attending the Leprosy Hospital, Mohakhali, Dhaka. Patients were divided into two groups; paucibacillary (70%) group and multibacillary (30%) group. PCR showed 100% positivity in skin and ear lobule and 73.4% positivity in nasal smear of multibacillary group. PCR was positive in 40%, 25.7% and 11.4% in skin lesion, ear lobule and nasal swab in paucibacillry group respectively.

Result: Compared with other diagnostic procedures, PCR showed clear advantages over both modified Z-N stain and auramine-phenol stain especially in paucibacillary patients.

Bangladesh J Med Microbiol 2020; 14 (1): 11-14
Colonization pattern of Gram positive organisms causing neonatal sepsis in pregnant women
Authors: Hasnat Hamima , Afroz Sadia , Islam Faijul , Hossain Mohammad Monir , Paul Shikha
Published: January 2022

Background: Neonatal sepsis is one of the major causes of mortality and morbidity in neonates. Early onset neonatal sepsis (EONS) is commonly caused by mother’s vaginal and rectal organisms before or during the delivery process.

Objective: The aim of this study was to determine the colonization pattern of common gram positive organisms responsible for neonatal sepsis, in women of 35-37 weeks of pregnancy.

Methodology: A cross sectional analytical study was conducted from July 2018 to June 2019 at the department of Microbiology of Sir Salimullah Medical College, Dhaka. Total 107 of each vaginal and vaginorectal samples was collected from pregnant women at 35-37 weeks of pregnancy attending at the out-patient department of the Obstetrics and Gynaecology unit of Sir Salimullah Medical College & Mitford Hospital, Dhaka. Vaginal and vaginorectal samples were tested by standard culture technique using Todd– Hewitt broth, blood agar, High chrome UTI agar media. Data was collected by a questionnaire and results were analyzed by statistical package for the social sciences (SPSS) program.

Results: In this study, among 107 vaginal swab samples Staphylococcus aureus were the predominant isolate (51.40%), followed by Enterococci (20.56%), Coagulase negative Staphylococcus (14.95%) and Group B Sreptococcus (5.61%). Similarly among 107 vaginorectal swab samples commonest isolates were Staphylococcus aureus (56.1%), followed by Enterococci (52.34%), Coagulase negative Staphylococcus (11.21%) and Group B Streptococcus (6.54%).

Conclusion: The organisms from the vaginal and vaginorectal swabs were essentially the same. Staphylococcus aureus and Enterococci were the most abundant organisms that can cause neonatal sepsis, isolated from the vaginal and vaginorectal swab samples.

Bangladesh J Med Microbiol 2020; 14 (2): 12-18
Quality Assurance in the molecular diagnostic laboratory
Authors: Farook Saika , Siddiqui Tanvir Ahmed , Mondal Pritylata , Anwar Shaheda
Published: January 2022

Molecular diagnostics is currently playing an imperative role in the clinical microbiology laboratory. Quality assurance and quality control issues have often remained underdeveloped in our country and are still critical. To relate patient results to these, molecular diagnostics carry values in clinical diagnosis, therapeutic drug monitoring and remission and those results need to be comparable across time and methods. This may be achieved either by producing the identical value across methods and test versions or by using reliable and stable reference materials in the medical laboratories engaged with molecular tests. The establishment of international standards and reference materials, assessment and maintenance of technical competencies, regulatory oversight and best practices considerations are thus of utmost importance. This review focuses on general and specific issues relevant for quality assurance and quality control in the routine molecular diagnostics laboratory.

Bangladesh J Med Microbiol 2021; 15 (1): 30-34
Percepción sobre educación virtual en estudiantes universitarios de Ciencias de la Salud, en tiempos de COVID-19
Authors: Callasaca-Goyzueta Jackelin , Gutiérrez-Pantigoso Kimberly , Cotrado-Estalla Edith , Campos-Condori Helbert , Ayhuasi-Gomez Keidy , Velarde-Quispe Rubí , Huanco Apaza Diana
Published: January 2022

Objetivo: Conocer la percepción de estudiantes universitarios de Ciencias de la Salud sobre la educación virtual. Material y métodos: Estudio descriptivo en 293 estudiantes de la Facultad de Ciencias de la Salud de la Universidad Nacional Jorge Basadre Grohmann en Tacna, Perú, durante el segundo semestre del año 2020. Se aplicó un cuestionario virtual previo consentimiento informado con 26 preguntas cerradas. Se utilizó estadística descriptiva y los datos se analizaron con STATA versión 16. Resultados: En el desarrollo de clases virtuales, los estudiantes utilizan con mayor frecuencia celular (65 %) y laptop (62,4 %), con internet inalámbrico (59,3 %). El 87,7 % percibió que su enseñanza y su formación se ha visto afectada y es insuficiente, debido a la falta de adaptación del docente a esta modalidad y a la falta de recursos audiovisuales para la práctica clínica (73,4 %); consideran muy importante que las clases prácticas sean presenciales (91,1 %). Se presentaron efectos negativos en la situación socioeconómica de los alumnos (54,6 %) e incertidumbre sobre su futuro académico. Los estudiantes percibieron problemas en su salud mental principalmente estrés (30,3 %) y ansiedad (21,5 %); incluso malestares físicos como dolor de espalda (21,8 %) y ardor de ojos (21,6 %). Conclusión: La percepción de estudiantes universitarios de Ciencias de la Salud frente a la educación virtual en torno a diferentes condiciones del aprendizaje es negativa. Sugieren retor no a clases presenciales principalmente para la práctica clínica.
Medidas de bioseguridad y miedo a la COVID-19 asociado a calidad de vida en el trabajo en personal asistencial de salud de un hospital
Authors: Llerena Torrejón Antony Alejandro , López Condori Obed Eleazar
Published: January 2022

Objetivo: Determinar la relación entre medidas de bioseguridad y miedo a la COVID-19 con la calidad de vida en el trabajo en personal asistencial de salud. Material y métodos: Estudio analítico transversal, se incluyó a 245 trabajadores asistenciales del Hospital Huaycán en Lima, Perú, quienes laboraron durante la pandemia de COVID-19. Se aplicó una encuesta online, durante el año 2021, compuesta por tres cuestionarios: medidas de bioseguridad, Fear of COVID-19 Scale para evaluar miedo y otro para medir calidad de vida en el trabajo. Se utilizó prueba Chi-cuadrado, T de Student, Odds Ratio (OR) con intervalo de confianza (IC) al 95 %, se consideró significativo cuando p < 0,05. Resultados: Los trabajadores presentaron media de edad de 38,6 ± 8,5 años, donde el 68,2 % son mujeres. El 61,6 % sí cumple medidas de bioseguridad en prevención de la COVID-19, el 81,6 % presentan mala calidad de vida en el trabajo, el 43,7 % tienen mucho miedo a la COVID-19 y el 48,2 % tiene miedo a perder la vida por COVID-19. El personal que tuvo miedo cuando ve noticias o historias sobre la COVID-19 tuvo 6 veces más riesgo de presentar mala calidad de vida en el trabajo (OR: 6,76; IC 95 %: 1,51-30,12), quienes no pueden dormir por estar preocupados por la COVID-19 tuvieron 5 veces más riesgo de presentar mala calidad de vida en el trabajo (OR: 5,51; IC 95 %: 1,10- 27,49). Conclusiones: El personal de salud usa regularmente medidas de bioseguridad, la mitad tienen miedo a la COVID-19; la mayoría tienen mala calidad de vida, la que se asocia al miedo por ver noticias o historias sobre la COVID-19 y no pueden dormir por estar preocupados por la COVID-19.
Kajian Faktor Pendukung Penumbuhan Mina Eduwisata (Studi Kasus di Kelurahan Tanjung Pauh Kecamatan Payakumbuh Barat Kota Payakumbuh Provinsi Sumatera Barat)
Authors: Yutra M Syaiful , Sunaryo Ade Sunaryo , Hanan Abdul , Junan Revelly
Published: January 2022

Mina Eduwisata adalah suatu konsep edukasi perikanan yang dipadukan dengan pariwisata dan berbasis pada suatu wilayah yang potensial. Upaya yang dilakukan dalam penumbuhan suatu wilayah menjadi kampung mina eduwisata adalah mulai dari perbaikan teknologi budidayanya. Salah satunya dengan inovasi penggunaan probiotik dari toga dan pemanfaatan pakan alami azolla microphylla. Penyuluhan merupakan langkah untuk menyampaikan informasi tentang teknologi sehingga sasaran atau pelaku utama bisa mengadopsi inovasi tersebut. Tujuan penelitian ini adalah membentuk kelurahan Tanjung Pauh sebagai Kampung Mina Eduwisata dengan penguatan dan pengembangan kegiatan budidaya lele melalui penggunaan teknologi probiotik, pemanfaatan pakan alami Azolla microphylla pada pembudidaya ikan nila, program-program ini dilakukan untuk dapat meningkatkan ekonomi dan meningkatkan pengetahuan, sikap serta memberdayakan masyarakat sekitar. Penelitian ini berlokasi di Kecamatan Payakumbuh Barat, Kota Payakumbuh, Sumatera Barat. Hasil penelitian menujukan bahwa Kelurahan Tanjung Pauh dikukuhkan menjadi Kampung Mina Eduwisata pada tanggal 14 Juni 2021.
Influence of Cochlear Implantation on Cognitive Function in Elderly Patients
Authors: Chung Juyong
Published: January 2022

Hearing loss is the third most common chronic health condition faced by older adults. Recently, a number of studies have demonstrated a significant association between hearing impairment and cognitive decline. However, the underlying explanatory mechanism of this relation has yet to be established. Given the relation between hearing loss and cognitive decline, researchers have been interested in the effect of restoring hearing ability on cognitive functions in older adults. One intervention option for management of the most severe to profound hearing loss in older adults is cochlear implantation (CI). We performed a review to assess the cur- rent status of the literature on the potential influence of CI on cognition in the older adults. Hearing rehabilitation through CI in elderly patients results in improvements in speech perception and cognitive function and lowers the progression to dementia. Further well-designed studies with long follow-up are needed to verify whether CI influences cognition in older adults.
Airport competition in Brazil’s northeast region
Authors: Domingos Maria Cecília de Farias , Falcão Viviane Adriano , Silva Francisco Gildemir Ferreira da
Published: January 2022

Aviation growth is mainly due to the integration between national and world economies in the global era. The capital’s airports of the Brazilian Northeast were managed by a federal public company and are currently being granted to private companies, which have the premise of expanding the number of passengers. The increase in number of passengers drives competition between airports, since they must have adequate infrastructure to contain the demand. The choice by the user for an airport can be evaluated based on factors such as access mode, air fares, availability of flights and airport infrastructure. This paper aims at evaluating the choice of passengers between two airports in the Northeast of Brazil since 2014 and how this choice has been changing over the years. The binomial logit model was used to obtain the probability of choosing between airports and to evaluate the most relevant factors. The results of the study presented that availability for direct flights, preference for airlines, access time, air fares and general satisfaction of the airport fluctuated in the choice of the two airports during the study period. By evaluating the likelihood of choice, subsidies are provided to improve services considered indispensable by passengers.
Guaraná (Paullinia cupana Kunth), marapuama (Ptychopetalum olacoides Benth.), genciana (Gentiana lutea L.), quassia (Quassia amara L.) e suas propriedades: uma breve revisão
Authors: Ferreira Fernando Augusto Morgado , Ferreira Bárbara Bragança , Bragança Vitor Augusto Nascimento , Lima Consuelo Lúcia Sousa de , Brasil Davi do Socorro Barros
Published: January 2022

A descoberta e o manejo de recursos naturais são essenciais no processo de desenvolvimento social. Por milhares de anos, a humanidade tem se utilizado de plantas com os mais diversos intuitos, como, por exemplo, para o alívio e a cura de enfermidades. A diversidade florística brasileira também possibilitou que as comunidades nativas adquirissem e desenvolvessem conhecimentos associados ao uso de inúmeros vegetais. Esta breve revisão da literatura tem por objetivo fazer um levantamento das propriedades de quatro espécies vegetais – guaraná (Paullinia cupana Kunth), marapuama (Ptychopetalum olacoides Benth.), genciana (Gentiana lutea L.), quassia (Quassia amara L.) – amplamente utilizadas pelos nativos da região amazônica, especialmente devido as suas propriedades terapêuticas. Destaca-se, por fim, a existência de grande potencial para o aprofundamento de pesquisas nas espécies vegetais revisadas, principalmente no que se refere ao uso fitoterápico – uma vez que essas tem mostrado, de acordo com fontes consultadas, auxiliar nos mais diversos quadros de saúde.
Profile of medication use during pregnancy: Results of the BRISA study, São Luís - MA, Brazil
Authors: Lima Renata Monteiro , Godinho Joseane Lima Prado , Magalhães Elma Izze da Silva , Brito Anaximandro Braga , Britto Maria Helena Seabra Soares de , Alves Maria Teresa Seabra Soares de Britto e , Santos Alcione Miranda dos
Published: January 2022

Objectives: To describe the medication profile used during pregnancy in a Brazilian capital. Methods: Descriptive cross-sectional study with data from BRISA study in São Luís, Maranhão. Participants were interviewed in hospitals and maternity hospitals after delivery and were asked about the use of medications during pregnancy. The drugs were classified according the Anatomical Therapeutic Chemical Classification and risk categories of the Food and Drug Administration. Results: 5,110 puerperal women were interviewed, of which 93.5% reported the use of at least one medication during pregnancy. The most frequent medications were: antianemic preparations (ferrous sulfate: 72.2%; iron and multivitamins: 4.9%, folic acid: 62.9% and associations with folic acid: 6.7%), vitamins (multivitamins and others minerals: 30.3%), analgesics (paracetamol: 12.3%), antibacterials for systemic use (cephalexin: 5.6%), antiemetics and anti-nauseating agents (scopolamine butylbromide: 5.4%) and antihypertensives (methyldopa): 3.6%). Among the drugs reported: 74.5% were from category A, 18.9% from category B, 5.5% from category C, 1.0% from category D and 0.1% from category X. Conclusions: Despite, the higher prevalence of medication use during pregnancy, most of which are considered safe in pregnancy. However, it is important that the use of drugs during pregnancy is monitored and guided by health professionals in order to ensure its rational use.
Healthcare waste management as a tool for human health protection: a mini review
Authors: Pimenta Ana Clara Muniz , Paixão Susana , Neves Arthur Couto , Mol Marcos Paulo Gomes
Published: January 2022

Healthcare wastes are generated by human or animal healthcare facilities. A small portion of these wastes are considered dangerous. However, accidents generated by incorrect waste management is a reality around the world. Accidents happen in different management stages, from the waste generation to its final destination, if waste is not properly managed. Therefore, this work aimed to discuss the possible problems related to the incorrect healthcare waste management, focusing on public health. This mini-review discussed some of the ways in which waste management can favor the preservation of public health and the environment, through steps such as minimization, segregation and recycling.
Aleitamento materno de prematuro: revisão integrativa de 2015 a 2020
Authors: Figueiredo Ana Carla Barbosa , Nascimento Marcia Helena Machado , Santos Valéria Regina Cavalcante dos , Soares Vanda Heloísa Marvão , Moraes Pilar Maria de Oliveira , Chermont Aurimery Gomes
Published: January 2022

O contexto do aleitamento materno vivenciado por mães de recém-nascidos prematuros constitui a questão norteadora deste artigo, considerando as necessidades de crescimento, desenvolvimento neurológico, estabilidade clínica  e controle da termorregulação para início da estimulação precoce da amamentação. Em contrapartida temos a condição sociocultural da mãe que necesita de apoio e orientações da equipe multiprofissional para travessia das situações advindas da internação de seu filho na unidade neonatal. Nesse caminho é indispensável propiciar a educação em saúde sobre a amamentação e os cuidados diários com o prematuro. Revisão integrativa da literatura sobre aleitamento materno em unidade neonatal no período de 2015 a 2020 realizada na Biblioteca Virtual em Saúde e bases de dados MEDLINE, LILACS e BDENF usandos os descritores em Ciências da Saúde (DeCS): aleitamento materno, recém-nascido prematuro, UTI neonatal; em seis etapas: elaboração da questão de revisão, busca dos artigos de acordo com critérios de inclusão e exclusão,  coleta de dados, análise crítica dos artigos selecionados, discussão dos resultados e apresentação da revisão. Selecionados 148 artigos, destes 20 artigos compuseram a revisão. Nível de evidência dos artigos incluídos: 05 meta-análises - Nível I, 07 estudos transversais - Nível IV, 06 estudos qualitativos descritivos e 02 revisões integrativas - Nível V. As evidências descritas nos artigos analisados corroboram que o aleitamento materno aliado as tecnologias da saúde disponíveis aumentam a sobrevida dos prematuros. Políticas e estratégias de fortalecimento voltadas para o aleitamento materno de prematuros devem ser implementadas nas políticas públicas de saúde.
Relationship between neuropsychiatric signs and symptoms and SARS-CoV-2 infection: an integrative review
Authors: Cavalcante Tahissa Frota , Damasceno Daniel Freitas Oliveira , Ferreira José Erivelton de Souza Maciel , Jansen Raphaella Castro , Barbosa Eloise da Silva , Moreira Rafaella Pessoa , Morais Huana Carolina Cândido
Published: January 2022

Introduction: Several viruses, including CoVs, can affect the nervous system, causing neuropsychiatric signs and symptoms. Because this is an unknown disease widely spread, there are few studies that deal with the effects of the SARS-CoV-2 on the nervous system. Objective: To describe the relationship between neuropsychiatric signs and symptoms and SARS-Cov-2 virus infection. Methods: integrative review conducted in the Pubmed Portal, Virtual Health Library, Cochrane and the academic researcher Science Direct. The works were analyzed qualitatively, with the narrative description divided into four thematic categories. Results: 1024 studies were found and 48 studies selected to compose this integrative review. There is a pathophysiological relationship of SARS-Cov-2 infection and the involvement of the Central Nervous System and Peripheral Nervous System through different pathways and mechanisms. Conclusion: Monitoring patients during and after COVID-19 can minimize the neuropsychiatric sequelae resulting from this disease, especially in elderly patients with comorbidities.
A influência da música no consumo dos alimentos
Authors: Xavier Patrícia Santos , Gomes Larissa Rodrigues , Amaral Tatiana , Costa Joyce Maria Gomes da
Published: January 2022

O presente estudo visa apresentar como a temática música influencia a escolha dos alimentos pelos consumidores, seja de forma consciente, ou inconsciente, além de revelar como a música excede os limites de partituras, instrumentos e ruídos ao alcance de uma força vibracional que se espalha por todo lugar, exercendo ações sobre o homem as quais podem ser empregadas nas diversas ocasiões, principalmente nas áreas de percepção alimentar. A pesquisa foi realizada através de revisão bibliográfica com artigos de estudos sobre o tema proposto no intuito de contribuir às referências aos efeitos musicais e mentais. Várias linhas de pesquisa baseiam-se em experimentos conduzidos com grupos de pessoas a demonstrar como a influência sonora reflete no consumo dos alimentos. Tais resultados revelam que a música ocasiona alterações em nossos sentidos e humor, interferindo diretamente no sabor e na escolha dos alimentos pelo consumidor.
Análise de viabilidade de inserção de Fibra de Coco em Tijolos de Solo-Cimento
Authors: Neves Isamara Coelho , Cota Karolayne Gonçalves , Cabral Stênio Cavalier , Oliveira Ismael Abu Kamel Marques de
Published: January 2022

Com o passar dos anos a engenharia civil foi evoluindo em questão de técnicas construtivas e materiais práticos utilizados com o intuito de facilitar e baratear a obra. O impacto ambiental, quando começou a ser questionado, gerou muitas críticas ao setor de construção civil, pelo desperdício de materiais e dificuldade da destinação destes. O tijolo solo-cimento veio como uma alternativa sustentável para o meio ambiente, já que é considerado ecologicamente correto. Assim, este estudo tem como objetivo produzir tijolos de baixo custo, utilizando em sua composição fibras de coco e solo da região de Teófilo Otoni, a fim de discutir e avaliar a influência destes compostos nas propriedades do material e estudar sua viabilidade econômica e ambiental. Na metodologia deste trabalho foi realizada a confecção do tijolo solo-cimento com adição de fibras de coco. Foram confeccionados tijolos com e sem fibra com o intuito de realizar ensaios laboratoriais de compressão, a fim de discutir a influência da fibra no tijolo. Com relação à resistência à compressão, a inserção das fibras possibilitou um ganho significativo, sendo que os tijolos com fibra apresentaram cerca de 4,5 vezes mais resistência que aqueles sem fibra. Portanto conclui-se que os tijolos fabricados suprem as expectativas desejadas, permitindo a produção de um material que se enquadre no padrão de preocupações com o meio ambiente, viabilidade de uma forma de emprego e o aumento da resistência à compressão.
First report of fungal Sporothrix schenckii complex isolation from feline with possible zoonotic transmission in the city of Belém, Pará, Brazil: Case report
Authors: Silva Barbara Wilka Leal , Maués Marcelino Antônio Costa , Barrozo Pedro Henrique Marques , Brito Jacqueline da Silva , Souza Caio Cezar Nogueira de , Rosário Marcely Karen Santos do , Santos Caroliny do Socorro Brito , Queiroz Neta Alzira Alcantara Mendes , Martins Fernanda Monik Silva , Silva Leonildo Bento Galiza da , Casseb Lívia Medeiros Neves , Negrão Andréa Maria Góes , Guimarães Mylenna de Cássia Neves , Cruz Andrea Viana da , Casseb Alexandre do Rosário
Published: January 2022

Feline sporotrichosis is a subcutaneous, infectious, and contagious mycosis, with zoonotic characteristics. Until now there are no reports on the isolation of Sporothrix sp. in cats in the state of Pará. The present work aimed to isolate Sporothrix spp. from a cat with possible zoonotic involvement in the city of Belém, Pará. Through the active search for suspected cases of sporotrichosis, carried out by members of the Center for the Control of Zoonoses of Belém (CCZ, Belém) the suspicion of the disease in a feline was reported, with probable transmission to its owner. Clinical evaluation was performed, and biological material was collected from the animal for identifying the agent. Microscopic evaluation of the collected sample and microbial culture confirmed the presence of Sporothrix sp. in the sample. This study is the first to report the microbiological isolation of Sporothrix sp. in a cat in the metropolitan region of Belém, Pará, with possible zoonotic transmission. This indicates a probable underreporting of cases, an unknowing regarding the reality of health conditions and the need for more accurate and comprehensive evaluation of sporotrichosis in this region.
Diagnóstico parasitológico da Tristeza Parasitária Bovina na Bahia – Estudo retrospectivo de 2017 a 2021
Authors: Silva Regiane Pereira Benevides , Pacheco Leonardo Ribas , Lima Tiago Silva , Oliveira Raquel Moreira , Souza Melyssa Silva , Barbosa Cristiane de Jesus , Ribas Jorge Raimundo Lins , Barbosa Luciana Veiga
Published: January 2022

A Tristeza Parasitária Bovina (TPB), causada por Babesia bovis e B. bigemina em conjunto com a Anaplasma marginale, é responsável por causar prejuízos à bovinocultura nacional. Disseminada em todas as regiões do Brasil, estima-se que a TPB gerou um gasto de cerca de 3,5 milhões de dólares para a bovinocultura nacional no ano de 2019. O objetivo deste trabalho foi realizar um estudo retrospectivo considerando os anos de 2017 a 2021, sobre a ocorrência desses hemoparasitas por meio de análises citológicas de esfregaços sanguíneos em rebanhos bovinos provenientes de quatro propriedades nos municípios do Prado, Jucuruçu, São Sebastião do Passé e São Miguel das Matas, estado da Bahia/Brasil. Foi observada a presença de Babesia spp. nas propriedades do Prado (3,0%), Jucuruçu (7,4%), e em São Sebastião do Passé (63,7%), sendo que nesse último município, foi igualmente observada uma elevada ocorrência de A. marginale (44,0%) inclusive com coinfecção (8,9%). Não foi detectada nenhum dos hemoparasitos causadores da TPB na propriedade em São Miguel das Matas. Esse estudo mostra a importância das análises citológicas de esfregaços sanguíneos na identificação desses hemoparasitas visando embasar medidas preventivas por parte das agências sanitárias do Estado no sentido de evitar a exposição de animais aos agentes da TPB.
Atividades lúdico-educativas sobre Infecções Sexualmente Transmissíveis: uma proposta de Divulgação Científica no ambiente escolar
Authors: Martins Ariele da Silva , Silva Marcella Larrate da , Amaral Thamyris  Figueiredo do , Belo Mariana Soares da Silva Peixoto , Silva Bianca Ramos Marins , Costa Patricia Cristina dos Santos
Published: January 2022

Divulgação Científica (DC) é um método de difusão do conhecimento científico-acadêmico cujo objetivo é democratizar o acesso à informação e estimular o desenvolvimento de senso crítico, atingindo diferentes públicos. A utilização de práticas lúdico-educativas como método de divulgação faz-se necessária para um aprendizado mais dinâmico e com maior desenvolvimento cognitivo. Reforça ainda as instituições de ensino como importantes promotoras de ações educativas, especialmente em saúde. Sabendo que os adolescentes estão entre os grupos mais vulneráveis e possuem defasagem de conhecimento básico quanto às Infecções Sexualmente Transmissíveis (IST), a adoção de intervenções mais efetivas acerca do tema é crucial. Assim, com esse trabalho, objetiva-se propor estratégias de DC em espaços escolares através de atividades lúdico-educativas sobre IST como ferramenta pedagógica e promotora da saúde. Esta proposta de divulgação científica é composta por estratégias de ensino, diferentes do modelo expositivo tradicional, tais como a promoção de conhecimento por meio de informações básicas e preventivas sobre essas infecções e seus impactos na saúde; ações interativas através de jogos de perguntas e respostas intitulados “Jogo de Tabuleiro Humano”, “Quiz Torta na Cara” e “Ida ao Posto de Saúde”; e divulgação das unidades locais de Atenção Primária à Saúde. Essas atividades lúdicas são relevantes por estimularem a participação e trabalho em equipe dos estudantes envolvidos, além de favorecerem ao processo de ensino-aprendizagem mais atrativo e criativo, questões fundamentais para a prática de ações promotoras da saúde no ambiente escolar.
Tecnologia digital versus convencional para confecção de próteses totais: uma revisão sistemática
Authors: Freitas Larissa Costa , Oliveira Flávia Braga de , Lima Camila Moreira , Miranda Jean Soares , Leite Fabíola Pessôa Pereira
Published: January 2022

Objetivo: Avaliar se a tecnologia CAD/CAM é superior a técnica convencional para confecção de próteses totais mucosuportadas. Metodologia: Esta revisão seguiu as recomendações do PRISMA. Foi realizada, por dois revisores calibrados, uma revisão sistemática nas bases de dados Medline-PubMed, Scopus, Scielo, Lilacs, Web of Science e Cochrane Library, usando os descritores: “Complete denture”, “Complete dentures”, “Total denture”, “Total dentures”, “Complete prosthesis”, “Complete prostheses”, “Total prosthesis”, “Total prostheses”, “Computer Aided Design”, “Computer Aided Manufacturing”, “CAD/CAM”, ‘’Benefits” e “Advantage”. Foram incluídos apenas estudos in vitro que comparavam a tecnologia CAD/CAM (impressão ou fresagem) com a confecção convenvional e excluídos trabalhos sem grupo controle e de próteses sobre implantes. Resultados: A estratégia utilizada resultou em 410 artigos. Destes, 11 se encaixavam nos critérios de inclusão. Após leitura na íntegra, apenas 6 foram incluídos na revisão sistemática. Apesar de exigir um alto investimento e capacitação profissional, os estudos selecionados demonstraram as próteses Conclusão: O processo de fabricação de prótese total por meio do sistema CAD/CAM apresentou-se vantajoso, comparado ao método convencional, sendo a principal delas a menor liberação de monômero, acompanhado de melhores qualidades biomecânicas e adaptação marginal, apesar do seu alto custo.
Panagrellus redivivus: um promissor nematoide para aulas práticas de Biologia celular
Authors: Stefanello Larissa , Loreto Elgion Lucio da Silva
Published: January 2022

A teoria celular condensa estudos sobre origem, composição e funcionamento das células. Os primeiros contribuintes dessa teoria foram Matthias Schleiden e Theodor Schwann que, por meio de seus estudos, concluíram que todos os seres vivos são formados por células. A compreensão de conceitos básicos de biologia celular é fundamental para o aprendizado da fisiologia, reprodução, hereditariedade, propagação de doenças e interações entre os seres vivos. Por isso, do ensino fundamental ao ensino médio, as disciplinas de ciências abordam tópicos de citologia. Todavia, esses são tratados de forma predominantemente teórica. Aulas práticas são extremamente importantes para a alfabetização científica e devem ser realizadas desde o ensino básico. Contudo, há uma carência de experimentos que permitam a visualização de células animais em tecidos vivos. Frente a isso, esse artigo propõe uma aula prática, utilizando o verme Panagrellus redivivus, com o objetivo de elucidar a multicelularidade, bem como a formação de novas células e do ser vivo por meio da embriogênese. Esse nematoide é de fácil obtenção e o manuseio é feito utilizando materiais de baixo custo, mas o ganho em aprendizagem é muito alto. Acredita-se que a utilização desse modelo experimental não só facilite o entendimento do tópico proposto, como também auxilie e incentive a formação científica dos discentes.
Avaliação da prematuridade em Hospital Amigo da Criança no interior de Sergipe no ano de 2019
Authors: Sacramento Alexa Aragão do , Lopes Izailza Matos Dantas
Published: January 2022

A prematuridade é uma síndrome clínica complexa, com múltiplos fatores etiológicos, e está associada a um amplo espectro de condições clínicas correlacionadas à sobrevida e aos padrões de crescimento e desenvolvimento, definidos a partir do nascimento de crianças com idade gestacional menor do que 37 semanas. O presente estudo, de caráter epidemiológico, retrospectivo, transversal e de caráter analítico, objetivou identificar o perfil de mães e de prematuros nascidos vivos em uma maternidade no interior do estado de Sergipe. Os dados analisados foram obtidos por meio do sistema de informações sobre nascidos vivos (SINASC), com base nas declarações de nascidos vivos. Sua análise apontou que a maior parte das mães estava, respectivamente na faixa-etária de 20 a 24 anos (28,5%); na de 25 a 28 anos (27,3%); e na de 10 a 19 anos (20,2%). No momento do nascimento das crianças, essas mulheres estavam em união consensual (70,4%), ou eram casadas (14,9%). Um grupo menor de mães registradas no SINASC era comporto por mulheres solteiras (12,7%), separadas judicialmente, viúvas ou ignorado (1,1%) (p < 0,05). No que tange ao pré-natal, 68,5% das mulheres tiveram um acompanhamento considerado mais do que adequado, com 7 ou mais consultas médicas (p < 0,05). APGAR dos recém-nascidos (a maioria apresentou pontuação entre 8 a 10, no primeiro e no quinto minuto de vida (p < 0,05). Os resultados da análise executada neste estudo sinalizaram a importância da identificação dos principais fatores de risco para o parto prematuro, e apontaram que esse quadro é menos frequente entre gestantes que mantém relação consensual ou são casadas. Por isso, um pré-natal adequado, bem como o conhecimento do perfil dessas mulheres, é de suma importância, pois desse modo é possível detectar as principais causas de parto prematuro e evitar o seu acontecimento.
Back school and postural habits of women from the Tabajara indigenous community: a quali-quantitative, participatory, and ethnographic approach
Authors: Silva Gilza de Holanda da , Parizotto Nivaldo Antonio , Cardia Maria Claudia Gatto , Barreto Juerila Moreira
Published: January 2022

Objectives: The Back School is a therapeutic-pedagogical method for the preservation of good postural habits, reeducation of posture and prevention of pain in the spine. To know the postural habits of the Tabajara indigenous community through the realization of a sensitization workshop on care of the spine. Methods: This is an action, participatory and ethnographic research with a qualitative/quantitative approach. Fourteen women aged between 18 and 70 years participated. The instruments were inventory of correct and incorrect postural images and postural assessment form. Conclusion: The sum of the posture frequency was 165 to inadequate postures and 92 for appropriate postures. Qualitative analysis highlights that in the CIs of the questions: What are your expectations regarding this work? 78.6%= Learning the new; Have your expectations been met? 92.8%= Learning; Did the spine theme addressed contribute to improve your self-knowledge? 85.7%= Correct use of the spine; How do you feel at the end of the event? 85.7%= Emotional satisfaction; Pain in your spine? 85.7%= feel pain. Practice implications: The study showed that there is involvement in the spine with pain, which may be related to inadequate postures, and it can change using education for health approach.