bluuebunny/crossref_metadata_2025 huggingface dataset:
Snorkeling Strategy: Tolerance to Flooding in Rice and Potential Application for Weed Management
Authors: Kaspary Tiago Edu , Roma-Burgos Nilda , Merotto Aldo
Published: August 2020

Flooding is an important strategy for weed control in paddy rice fields. However, terrestrial weeds had evolved mechanisms of tolerance to flooding, resulting in new ‘snorkeling’ ecotypes. The aim of this review is to discuss the mechanisms of flooding tolerance in cultivated and weedy rice at different plant stages and the putative utility of this trait for weed management. Knowledge about flooding tolerance is derived primarily from crop models, mainly rice. The rice model informs us about the possible flooding tolerance mechanisms in weedy rice, Echinochloa species, and other weeds. During germination, the gene related to carbohydrate mobilization and energy intake (RAmy3D), and genes involved in metabolism maintenance under anoxia (ADH, PDC, and OsB12D1) are the most important for flooding tolerance. Flooding tolerance during emergence involved responses promoted by ethylene and induction of RAmy3D, ADH, PDC, and OsB12D1. Plant species tolerant to complete submersion also employ escape strategies or the ability to become quiescent during the submergence period. In weedy rice, the expression of PDC1, SUS3, and SUB1 genes is not directly related to flooding tolerance, contrary to what was learned in cultivated rice. Mitigation of flooding tolerance in weeds could be achieved with biotechnological approaches and genetic manipulation of flood tolerance genes through RNAi and transposons, providing a potential new tool for weed management.
Use of Customizable Nucleases for Gene Editing and Other Novel Applications
Authors: Reddy Pradeep , Vilella Felipe , Izpisua Belmonte Juan Carlos , Simón Carlos
Published: August 2020

The development of novel genome editing tools has unlocked new opportunities that were not previously possible in basic and biomedical research. During the last two decades, several new genome editing methods have been developed that can be customized to modify specific regions of the genome. However, in the past couple of years, many newer and more exciting genome editing techniques have been developed that are more efficient, precise, and easier to use. These genome editing tools have helped to improve our understanding of genetic disorders by modeling them in cells and animal models, in addition to correcting the disease-causing mutations. Among the genome editing tools, the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system has proven to be the most popular one due to its versatility and has been successfully used in a wide variety of laboratory animal models and plants. In this review, we summarize the customizable nucleases currently used for genome editing and their uses beyond the modification of genome. We also discuss the potential future applications of gene editing tools for both basic research and clinical purposes.
The Investigation of Perennial Sunflower Species (Helianthus L.) Mitochondrial Genomes
Authors: Makarenko Maksim , Usatov Alexander , Tatarinova Tatiana , Azarin Kirill , Kovalevich Alexey , Gavrilova Vera , Horn Renate
Published: August 2020

The genus Helianthus is a diverse taxonomic group with approximately 50 species. Most sunflower genomic investigations are devoted to economically valuable species, e.g., H. annuus, while other Helianthus species, especially perennial, are predominantly a blind spot. In the current study, we have assembled the complete mitogenomes of two perennial species: H. grosseserratus (273,543 bp) and H. strumosus (281,055 bp). We analyzed their sequences and gene profiles in comparison to the available complete mitogenomes of H. annuus. Except for sdh4 and trnA-UGC, both perennial sunflower species had the same gene content and almost identical protein-coding sequences when compared with each other and with annual sunflowers (H. annuus). Common mitochondrial open reading frames (ORFs) (orf117, orf139, and orf334) in sunflowers and unique ORFs for H. grosseserratus (orf633) and H. strumosus (orf126, orf184, orf207) were identified. The maintenance of plastid-derived coding sequences in the mitogenomes of both annual and perennial sunflowers and the low frequency of nonsynonymous mutations point at an extremely low variability of mitochondrial DNA (mtDNA) coding sequences in the Helianthus genus.
A Comparative Study of Supervised Machine Learning Algorithms for the Prediction of Long-Range Chromatin Interactions
Authors: Vanhaeren Thomas , Divina Federico , García-Torres Miguel , Gómez-Vela Francisco , Vanhoof Wim , Martínez-García Pedro Manuel
Published: August 2020

The role of three-dimensional genome organization as a critical regulator of gene expression has become increasingly clear over the last decade. Most of our understanding of this association comes from the study of long range chromatin interaction maps provided by Chromatin Conformation Capture-based techniques, which have greatly improved in recent years. Since these procedures are experimentally laborious and expensive, in silico prediction has emerged as an alternative strategy to generate virtual maps in cell types and conditions for which experimental data of chromatin interactions is not available. Several methods have been based on predictive models trained on one-dimensional (1D) sequencing features, yielding promising results. However, different approaches vary both in the way they model chromatin interactions and in the machine learning-based strategy they rely on, making it challenging to carry out performance comparison of existing methods. In this study, we use publicly available 1D sequencing signals to model cohesin-mediated chromatin interactions in two human cell lines and evaluate the prediction performance of six popular machine learning algorithms: decision trees, random forests, gradient boosting, support vector machines, multi-layer perceptron and deep learning. Our approach accurately predicts long-range interactions and reveals that gradient boosting significantly outperforms the other five methods, yielding accuracies of about 95%. We show that chromatin features in close genomic proximity to the anchors cover most of the predictive information, as has been previously reported. Moreover, we demonstrate that gradient boosting models trained with different subsets of chromatin features, unlike the other methods tested, are able to produce accurate predictions. In this regard, and besides architectural proteins, transcription factors are shown to be highly informative. Our study provides a framework for the systematic prediction of long-range chromatin interactions, identifies gradient boosting as the best suited algorithm for this task and highlights cell-type specific binding of transcription factors at the anchors as important determinants of chromatin wiring mediated by cohesin.
Novel Germline c.105_107dupGCT MEN1 Mutation in a Family with Newly Diagnosed Multiple Endocrine Neoplasia Type 1
Authors: Stasiak Magdalena , Dedecjus Marek , Zawadzka-Starczewska Katarzyna , Adamska Emilia , Tomaszewska Monika , Lewiński Andrzej
Published: August 2020

In multiple endocrine neoplasia type 1 (MEN1), the causative MEN1 gene mutations lead to the reduced expression of menin, which is a tumor suppressor protein. In this study, we present a case of a 16-year-old woman with severe primary hyperparathyroidism and a non-functioning pituitary microadenoma. Genetic testing demonstrated a novel germline heterozygote variant c.105_107dupGCT of MEN1, leading to Leu duplication in position 37 of the menin polypeptide chain. As such a mutation was not reported before as a causative one, confirmation of its pathogenicity required showing the same mutation in a symptomatic first-degree relative. An identical mutation was found in the patient’s father, who was further diagnosed with hyperparathyroidism and a pituitary microadenoma. We observed the presence of the same MEN1-related tumors but an entirely different symptom severity. To the best of our knowledge, this is the first report of MEN1 syndrome caused by the c.105_107dupGCT MEN1 mutation. This case report demonstrates the importance of genetic evaluation towards MEN1. Genetic testing for MEN1 mutations should be performed in all patients with MEN1-related tumors, and in the young patients even with only one such tumor, despite the supposedly negative family history.
Integrated Archaeological Research: Archival Resources, Surveys, Geophysical Prospection and Excavation Approach at an Execution and Burial Site: The German Nazi Labour Camp in Treblinka
Authors: Różycki Sebastian , Zapłata Rafał , Karczewski Jerzy , Ossowski Andrzej , Tomczyk Jacek
Published: August 2020

This article presents the results of multidisciplinary research undertaken in 2016–2019 at the German Nazi Treblinka I Forced Labour Camp. Housing 20,000 prisoners, Treblinka I was established in 1941 as a part of a network of objects such as forced labour camps, resettlement camps and prison camps that were established in the territory of occupied Poland from September 1939. This paper describes archaeological research conducted in particular on the execution site and burial site—the area where the “death pits” have been found—in the so-called Las Maliszewski (Maliszewa Forest). In this area (poorly documented) exhumation work was conducted only until 1947, so the location of these graves is only approximately known. The research was resumed at the beginning of the 21st century using, e.g., non-invasive methods and remote-sensing data. The leading aim of this article is to describe the comprehensive research strategy, with a particular stress on non-invasive geophysical surveys. The integrated archaeological research presented in this paper includes an analysis of archive materials (aerial photos, witness accounts, maps, plans, and sketches), contemporary data resources (orthophotomaps, airborne laser scanning-ALS data), field work (verification of potential objects, ground penetrating radar-GPR surveys, excavations), and the integration, analysis and interpretation of all these datasets using a GIS platform. The results of the presented study included the identification of the burial zone within the Maliszewa Forest area, including six previously unknown graves, creation of a new database, and expansion of the Historical-GIS-Treblinka. Obtained results indicate that the integration and analyses within the GIS environment of various types of remote-sensing data and geophysical measurements significantly contribute to archaeological research and increase the chances to discover previously unknown “graves” from the time when the labour camp Treblinka I functioned.
Chronic Obstructive Pulmonary Disease and Dysphagia: A Synergistic Review
Authors: Lin Ting-fen , Shune Samantha
Published: August 2020

Chronic obstructive pulmonary disease (COPD) is a leading global cause of death and disability. The literature has previously established clear physiological characteristics of COPD-related dysphagia (swallowing difficulties). However, COPD and dysphagia are both also intimately tied to breathing and contribute to a cascade of secondary physio-psycho-emotional sequalae, such as COPD exacerbation, anxiety, depression, increased economic burden, social isolation, and decreased quality of life. Further, the collective impact of these comorbidities may magnify disease impact, resulting in a downward spiral of well-being. Thus, the clinical relevance of COPD’s and dysphagia’s frequently occurring and overlapping sequelae cannot be overlooked, as the disease-related burden of both disorders is deeply rooted in the presence of concomitant physiological and psycho-emotional consequences. The current review explores the complex network of interactions between COPD, dysphagia, and their outcomes, framing this relationship within a mind-body-breath framework. Ultimately, we propose a model that more comprehensively captures the constellation of interrelated disease characteristics and consequences, highlighting a need for researchers and healthcare providers to consider disease impact more broadly in order to maximize treatment outcomes.
The Nutritional Status of Adult Antiretroviral Therapy Recipients with a Recent HIV Diagnosis; A Cross-Sectional Study in Primary Health Facilities in Gauteng, South Africa
Authors: Mahlangu Khabo , Modjadji Perpetua , Madiba Sphiwe
Published: August 2020

The study determined the nutritional status of adult antiretroviral therapy (ART) recipients, and investigated the association between the duration on ART and the nutritional status. This study was based in primary health facilities in Gauteng, South Africa. The data collected included sociodemographic variables; the duration of the treatment; and the body mass index (BMI), classified as undernutrition (<18.5 kg/m2), normal (18.5–24.9 kg/m2), or overweight/obesity (≥25 kg/m2). ART recipients (n = 480) had a mean age of 35 (± 8.4SD) years. All had taken ART for six months or more (range 6–48 months). The data were analyzed using STATA 13.0. The overall prevalence of overweight/obesity was 39%, it was higher in females (46%) than in males (30%), 26% were overweight, and 13% were obese. Underweight was 13%, and was higher in males (18%) than females (9%). Being overweight was more likely in those aged ≥35 years and those in smaller households. Being obese was less likely in males, in the employed, and in those with a higher income, but was more likely in those with a longer duration on ART. Abdominal obesity was high, but less likely in males. Interventions to prevent overweight/obesity should be integrated into routine HIV care, while at the same time addressing the burden of undernutrition among ART recipients.
Effect of an EMG–FES Interface on Ankle Joint Training Combined with Real-Time Feedback on Balance and Gait in Patients with Stroke Hemiparesis
Authors: Bae Subeen , Lee Jin , Lee Byoung-Hee
Published: August 2020

This study evaluated the effects of an electromyography–functional electrical stimulation interface (EMG–FES interface) combined with real-time balance and gait feedback on ankle joint training in patients with stroke hemiplegia. Twenty-six stroke patients participated in this study. All subjects were randomly assigned to either the EMG–FES interface combined with real-time feedback on ankle joint training (RFEF) group (n = 13) or the EMG–FES interface on ankle joint training (EF) group (n = 13). Subjects in both groups were trained for 20 min a day, 5 times a week, for 4 weeks. Similarly, all participants underwent a standard rehabilitation physical therapy for 60 min a day, 5 times a week, for 4 weeks. The RFEF group showed significant increases in weight-bearing lunge test (WBLT), Tardieu Scale (TS), Timed Up and Go Test (TUG), Berg Balance Scale (BBS), velocity, cadence, step length, stride length, stance per, and swing per (p < 0.05). Likewise, the EF group showed significant increases in WBLT, TUG, BBS, velocity, and cadence (p < 0.05). Moreover, the RFEF group showed significantly greater improvements than the EF group in terms of WBLT, Tardieu Scale, TUG, BBS, velocity, step length, stride length, stance per, and swing per (p < 0.05). Ankle joint training using an EMG–FES interface combined with real-time feedback improved ankle range of motion (ROM), muscle tone, balance, and gait in stroke patients. These results suggest that an EMG–FES interface combined with real-time feedback is feasible and suitable for ankle joint training in individuals with stroke.
A Decision Support Method for Prehospital Emergency Care Based on Ranking the Importance of Physiological Variables
Authors: Zhang Li , Zhao Shuying , Li Fang , Rao Guozheng
Published: August 2020

To the on-site nursing staff or field management in prehospital emergency care, it seems baffling to conduct more targeted checklist tests for a specific disease. To address this problem, we proposed a decision support method for prehospital emergency care based on ranking the importance of physiological variables. We used multiple logistic regression models to explore the effects of various physiological variables on diseases based on the area under the curve (AUC) value. We implemented the method on the intensive care database (i.e., the Medical Information Mart for Intensive Care (MIMIC-III) database) and explored the importance of 17 physiological variables for 24 diseases, both chronic and acute. We included 33,798 adult patients, using the full physiological dataset as experiment data. We ranked the importance of the physiological variables related to the diseases according to the experiments’ AUC value. We discussed which physiological variables should be considered more important in adult intensive care units (ICUs) for prehospital emergency care conditions. We also discussed the relationships among the diseases based on ranking the importance of physiological variables. We used large-scale ICU patient data to obtain a cohort of physiological variables related to specific diseases. Ranking a cohort of physiological variables is a cost-effective means of reducing morbidity and mortality under prehospital emergency care conditions.
Impacts of Cultural Diversity on Carbon Emission Effects: From the Perspective of Environmental Regulations
Authors: Song Ying-jie , Ma Fu-wei , Qu Jing-ya
Published: August 2020

Cultural diversity is an issue not considered too often in traditional research on the influencing factors of carbon emission reduction to give full play to the effective participation of micro subjects in environmental regulation and to achieve the carbon emission reduction target. Aiming at the cultural diversity of micro subjects, this paper introduces the provincial dynamic index of cultural diversity and, from the perspective of environmental regulation, combines environmental regulation types such as energy regulation, economic regulation, and administrative regulation, to empirically study the impact of cultural difference on carbon emission reduction. We found that cultural diversity had a significant negative impact on carbon emission effects, and there is a one-way Granger causality between the two. Cultural diversity and environmental regulations exerted a synergistic impact on carbon emission effects. Through specific mechanism tests, the intermediary effect of environmental regulations was confirmed. Cultural diversity influenced carbon emission effects through the mediation of environmental regulations. From the perspective of the refined characteristics of different regions, possible cultural diversity in the southern region and regional energy consumption characteristics significantly affected carbon emission effects. On the basis of the conclusions reached in this empirical research, we put forward the following policy suggestions: emphasis should be placed on the function of culture and other non-institutional factors in the practice of environmental regulations; bottom-up environmental protection incentives must be strengthened, and required expression channels should be perfected; the role of various environmental regulations must be given full play in the process of carbon emission reduction.
Effects of Pyramid Resistance-Training System with Different Repetition Zones on Cardiovascular Risk Factors in Older Women: A Randomized Controlled Trial
Authors: dos Santos Leandro , Ribeiro Alex S. , Nunes João Pedro , Tomeleri Crisieli M. , Nabuco Hellen C. G. , Nascimento Matheus A. , Sugihara Junior Paulo , Fernandes Rodrigo R. , Campa Francesco , Toselli Stefania , Venturini Danielle , Barbosa Décio S. , Sardinha Luís B. , Cyrino Edilson S.
Published: August 2020

This study analyzed the effects of the pyramidal resistance training (RT) system with two repetition zones on cardiovascular risk factors in older women (≥60 years old). Fifty-nine older women were randomly assigned in three groups: non-exercise control (CON, n = 19), narrow-pyramid system (NPR, n = 20), and wide-pyramid system (WPR, n = 20). Training was performed for eight weeks (eight exercises for the whole-body, 3x/week) in which NPR and WPR performed three sets of 12/10/8 and 15/10/5 repetitions, respectively. Regional body fat was estimated by dual-energy X-ray absorptiometry, and blood parameters related to glycemic, lipid, and inflammatory profiles were assessed. After the training period, although no difference was observed for the magnitude of the changes between NPR and WPR, significant group by time interactions indicated benefits with RT compared to CON for reducing body fat (mainly android body fat; −7%) and improving glucose, HDL-C, LDL-C and C-reactive protein (p < 0.05). Composite z-score of cardiovascular risk, created by the average of the intervention effects on the outcomes, indicate similar responses between NPR and WPR, differing from CON (p < 0.001). Results indicate that both the repetition zones of the pyramidal RT reduced similarly the cardiovascular risk in older women.
Safety and Effectiveness of Monochloramine Treatment for Disinfecting Hospital Water Networks
Authors: Marchesi Isabella , Paduano Stefania , Frezza Giuseppina , Sircana Luca , Vecchi Elena , Zuccarello Pietro , Oliveri Conti Gea , Ferrante Margherita , Borella Paola , Bargellini Annalisa
Published: August 2020

The formation of potentially carcinogenic N-nitrosamines, associated with monochloramine, requires further research due to the growing interest in using this biocide for the secondary disinfection of water in public and private buildings. The aim of our study was to evaluate the possible formation of N-nitrosamines and other toxic disinfection by-products (DBPs) in hospital hot water networks treated with monochloramine. The effectiveness of this biocide in controlling Legionella spp. contamination was also verified. For this purpose, four different monochloramine-treated networks, in terms of the duration of treatment and method of biocide injection, were investigated. Untreated hot water, municipal cold water and, limited to N-nitrosamines analysis, hot water treated with chlorine dioxide were analyzed for comparison. Legionella spp. contamination was successfully controlled without any formation of N-nitrosamines. No nitrification or formation of the regulated DBPs, such as chlorites and trihalomethanes, occurred in monochloramine-treated water networks. However, a stable formulation of hypochlorite, its frequent replacement with a fresh product, and the routine monitoring of free ammonia are recommended to ensure a proper disinfection. Our study confirms that monochloramine may be proposed as an effective and safe strategy for the continuous disinfection of building plumbing systems, preventing vulnerable individuals from being exposed to legionellae and dangerous DBPs.
Benchmarking the Nutrition-Related Policies and Commitments of Major Food Companies in Australia, 2018
Authors: Sacks Gary , Robinson Ella , Cameron Adrian J. , Vanderlee Lana , Vandevijvere Stefanie , Swinburn Boyd
Published: August 2020

The food industry has an important role to play in efforts to improve population diets. This study aimed to benchmark the comprehensiveness, specificity and transparency of nutrition-related policies and commitments of major food companies in Australia. In 2018, we applied the Business Impact Assessment on Obesity and Population Level Nutrition (BIA-Obesity) tool and process to quantitatively assess company policies across six domains. Thirty-four companies operating in Australia were assessed, including the largest packaged food and non-alcoholic beverage manufacturers (n = 19), supermarkets (n = 4) and quick-service restaurants (n = 11). Publicly available company information was collected, supplemented by information gathered through engagement with company representatives. Sixteen out of 34 companies (47%) engaged with data collection processes. Company scores ranged from 3/100 to 71/100 (median: 40.5/100), with substantial variation by sector, company and domain. This study demonstrated that, while some food companies had made commitments to address population nutrition and obesity-related issues, the overall response from the food industry fell short of global benchmarks of good practice. Future studies should assess both company policies and practices. In the absence of stronger industry action, government regulations, such as mandatory front-of-pack nutrition labelling and restrictions on unhealthy food marketing, are urgently needed.
The Moderated-Mediation Effect of Workplace Anxiety and Regulatory Focus in the Relationship between Work-Related Identity Discrepancy and Employee Innovation
Authors: Liu Chang-E , Hu Chenhong , Xie Wei , Liu Tingting , He Wei
Published: August 2020

Extant research on work-related identity discrepancy mostly has probed its effects on employees’ attitudes and emotions but has paid little attention to its impact on employee behaviors. Drawing on self-discrepancy theory, we examined the influencing mechanism and conditions of work-related identity discrepancy on employee innovation behavior. With data collected from 563 employees who personally experienced leadership transition in the workplace, we found that work-related identity discrepancy predicts employee innovation behavior through workplace anxiety. We also discovered that employees’ personality traits—promotion regulatory focus and prevention regulatory focus in particular—can intensify or buffer the negative relationship between work-related identity discrepancy and employee innovation behavior. We further discuss the conceptual and practical implications of these findings.
A Multiple Targeted Research Protocol for a Quasi-Experimental Trial in Primary School Children Based on an Active Break Intervention: The Imola Active Breaks (I-MOVE) Study
Authors: Masini Alice , Lanari Marcello , Marini Sofia , Tessari Alessia , Toselli Stefania , Stagni Rita , Bisi Maria Cristina , Bragonzoni Laura , Gori Davide , Sansavini Alessandra , Ceciliani Andrea , Dallolio Laura
Published: August 2020

Background: Children and adolescents should perform, according to the World Health Organization guidelines, at least 60 min of moderate-to-vigorous physical activity per-day in order to avoid the risk of metabolic and cardiovascular diseases. The school represents a fundamental setting to conduct interventions to promote physical activity (PA) and contrast sedentary behaviors. Active breaks (ABs), bouts of 10 min of PA conducted inside the classroom, seem to be a good strategy to promote PA and improve classroom behavior. The aim of this study protocol is to describe the design and the assessment of the Imola Active Breaks I-MOVE study. Methods: The I-MOVE study is a school-based intervention trial, with a quasi-experimental design, performed in a primary school. It involves one experimental-group performing the intervention, focused on ABs, and one control-group. Nine main outcomes are evaluated: PA and sedentary behaviors; health related fitness; motor control development; dietary patterns; anthropometric evaluation; sociodemographic determinants; cognitive function; time-on-task behavior and quality of life. Conclusions: Results from the I-MOVE study will help to clarify the effects of incorporating ABs in the Italian school curriculum as a new public health strategy and an innovative school model oriented to the well-being of children and teachers for the best quality of school life.
Health Benefits Derived from Forest: A Review
Authors: Grilli Gianluca , Sacchelli Sandro
Published: August 2020

In this paper the scientific literature on the association between forests, stress relief and relaxation is reviewed with the purpose to understand common patterns of research, the main techniques used for analysis, findings relevant to forest-therapy-oriented management, and knowledge gaps. The database of studies was collected with a keyword search on the Web, which returned a set of 32 studies that were included in the analysis. The main findings and patterns were identified with a text mining analysis of the abstract to search for keyword patterns across studies. The analysis indicates that most studies compared rest and relaxation performances across urban and forest environments and used a combination of self-reported measure of stress or rest collected with validate scales, e.g., the Profile of Mood of States (POMS) and the Restoration Outcome Scale (ROS), and a minority-only set of these two groups of indicators. Results of this review indicate that primary studies identified a positive association between forest exposure and mental well-being, in particular when compared to urban environments, thus suggesting that forest are effective in lowering stress levels. This study found that, to date, the characteristics of forests and characteristics of the visit are little investigated in the literature. For this reason, more research with a focus on forest variables such as tree species composition, tree density and other variables affecting forest landscape should be further investigated to inform forest management. Similarly, the characteristics of the visits (e.g., length of visit and frequency) should be further explored to provide robust forest therapy guidelines.
Eye-Level Street Greenery and Walking Behaviors of Older Adults
Authors: Zang Peng , Liu Xuhong , Zhao Yabo , Guo Hongxu , Lu Yi , Xue Charlie Q. L.
Published: August 2020

Evidence suggests that built environment characteristics affect older adults’ travel activity behaviors, e.g., walking and cycling, which have well-established health benefits. However, the relationship between urban greenery and walking behaviors remains unclear, partly due to methodological limitation. Previous studies often measured urban greenery from a bird’s eye perspective, which may mismatch with the pedestrian’s perception from the street. In this study, we measured greenery view index from eye-level streetscape photos retrieved from Baidu Street View, an online mapping service provider. Walking behaviors of 180 older adults in six neighborhoods were collected from questionnaires. We also measured land use diversity, pedestrian-oriented design (street connectivity), and population density—the three Ds of the built environment. Results show that street greenery view index contributes to walking time of older adults, suggesting street greenery should be taken into design consideration to promote walking behaviors of older adults.
Factors Associated with Prenatal Smoking Cessation Interventions among Public Health Nurses in Japan
Authors: Li Meng , Okamoto Reiko , Tada Aoki , Kiya Misaki
Published: August 2020

This study aimed to identify the factors associated with prenatal smoking cessation interventions based on the 5As model among public health nurses (PHNs) in Japan. A nationwide cross-sectional study was conducted from December 2019 to February 2020 via a self-administered questionnaire. The study subjects were 1988 PHNs working in 431 health centers of municipalities and special wards across the country. Of the 1988 questionnaires mailed, 521 responses (26.2%) were included in the analysis. Of the 521 responses, most of the respondents were female (98.1%) and the mean age was 37.5 years. There were statistically significant differences on age, work regions, experience years working as a PHN and smoking cessation training after becoming a PHN in implementing the 5As. Self-efficacy, professional development competency, research utilization competency, age and experience years working as a PHN were positively associated with the 5As. Social nicotine dependence was negatively associated with the 5As. Furthermore, self-efficacy mediated the relationship between the 5As and professional development competency, research utilization competency, social nicotine dependence, age and experience years working as a PHN. In the future, smoking cessation intervention training should be widely implemented to improve self-efficacy and prenatal smoking cessation interventions among Japanese PHNs.
Sex Differences in Frail Older Adults with Foot Pain in a Spanish Population: An Observational Study
Authors: Navarro-Flores Emmanuel , Romero-Morales Carlos , Becerro de Bengoa-Vallejo Ricardo , Rodríguez-Sanz David , Palomo-López Patricia , López-López Daniel , Losa-Iglesias Marta Elena , Calvo-Lobo César
Published: August 2020

Frailty is a condition that can increase the risk of falls. In addition, foot pain can influence older adults and affect their frail condition. The main objective was to measure the frailty degree in older adults in a Spanish population with foot pain from moderate to severe. Method: This is a cross-sectional descriptive study. A sample of people older than 60 years (n = 52), including 26 males and 26 females, were recruited, and frailty disability was measured using the 5-Frailty scale and the Edmonton Frailty scale (EFS). Results: Spearman’s correlation coefficients were categorized as weak (rs ≤ 0.40), moderate (0.41 ≤ rs ≥ 0.69), or strong (0.70 ≤ rs ≥ 1.00). There was a statistically significant correlation for the total score (p < 0.001) and most of the subscales of the 5-Frailty scale compared with the EFS, except for Mood (p > 0.05). In addition, females and males showed similar 5-Frailty and Edmonton Frail scales scores with no difference (p > 0.05). Conclusion: Foot pain above 5 points, i.e., from moderate to severe, does not affect the fragility more in one sex than another.
Hospice Employees’ Perceptions of Their Work Environment: A Focus Group Perspective
Authors: Lehto Rebecca H. , Heeter Carrie , Forman Jeffrey , Shanafelt Tait , Kamal Arif , Miller Patrick , Paletta Michael
Published: August 2020

Burnout in healthcare professionals can lead to adverse effects on physical and mental health, lower quality of care, and workforce shortages as employees leave the profession. Hospice professionals are thought to be at particularly high risk for burnout. The purpose of the study was to evaluate workplace perceptions of interdisciplinary hospice care workers who provide care to patients at end of life. Six focus groups and one semi-structured interview were conducted with mixed group of social workers, managers, nurses, hospice aides, chaplains, support staff, and a physician (n = 19). Findings from the groups depicted both rewards and challenges of hospice caregiving. Benefits included intrinsic satisfaction from the work, receiving positive patient and family feedback, and teamwork. Challenges reflected issues with workload, technology issues, administrative demands, travel-related problems, communication and interruptions, difficulties with taking time off from work and maintaining work-life integration, and coping with witnessing grief/loss. Hospice workers glean satisfaction from making meaningful differences in the lives of patients with terminal illness and their family members. It is an expected part of the job that certain patients and situations are particularly distressing; team support and targeted grief support is available for those times. Participants indicated that workload and administrative demands rather than dealing with death and dying were the biggest contributors to burnout. Participants reported episodic symptoms of burnout followed by deliberate steps to alleviate these symptoms. Notably, for all except one of the participants, burnout was cyclical. Symptoms would begin, they would take steps to deal with it (e.g., taking a mental health day), and they recovered. At an organizational level, a multipronged approach that includes both personal and occupational strategies is needed to support professional caregivers and help mitigate the stressors associated with hospice work.
Development and Implementation of a “Music Beeps” Program to Promote Physical Fitness in Adolescents
Authors: Jeong Hyun-Chul , Lee Eui-Jae , Youn Hyun-Su , So Wi-Young
Published: August 2020

This study aimed to develop a physical education fitness program for adolescents to counteract the declining physical activity levels caused by the COVID-19 pandemic, as well as to investigate the program’s effect. This mixed-methods study developed and implemented a five-component “Music Beeps” (MB) program to promote adolescents’ physical fitness. A total of 240 students from two high schools in South Korea—divided into experimental and control groups—participated in 32 sessions over 16 weeks. The changes in students’ fitness were analyzed, and the educational effects were examined via inductive analysis of the observation logs and group and in-depth interviews. The results demonstrated that, whereas the comparison group demonstrated no statistically significant changes in power, muscular strength and endurance, or cardiopulmonary endurance, the experimental group showed changes in all these variables, along with changes in flexibility. Further, the MB program had significant educational effects. First, students reported that musical cues enhanced their fitness motivation and sense of responsibility. Second, record-keeping and active participation contributed to self-led fitness management. Third, activity in a small space with few pieces of equipment led to the positive perception that the program was efficient and enabled regular exercise regardless of climate conditions.
Household Food Insecurity: Comparison between Families with and without Members with Disabilities
Authors: Park Jong Eun , Kim So Young , Kim Se Hee , Jeoung Eun Ju , Park Jong Hyock
Published: August 2020

Although the high rate of food insecurity among people with disabilities and their households has emerged as an important concern in public health and nutrition policy, the available data on these issues are still too limited to fully understand this phenomenon. This study aimed to compare the prevalence of food insecurity between households with and without persons with disabilities and to explore which sociodemographic and disability characteristics are associated with household food insecurity among households with members with disabilities. The data of 2690 households with and without members with disabilities from the 2013 Korea National Health and Nutrition Examination Survey were analyzed. Household food insecurity was more prevalent among households including persons with disabilities than among those without such members. The likelihood of experiencing food insecurity was especially high in households having a female head with a disability (odds ratio (OR) = 1.98); working-age adults with disabilities (OR = 1.70); members with disabilities who were not economically active (OR = 1.53); and members with mental disabilities (OR = 2.81), disabilities involving internal organs (OR = 4.38), or severe (grades 1–3) disabilities (OR = 1.73). The findings indicate that the disability status and sociodemographic characteristics of disabled family members are closely associated with household food security status.
The Effects of E-Cigarette Vapor Components on the Morphology and Function of the Male and Female Reproductive Systems: A Systematic Review
Authors: Szumilas Kamila , Szumilas Paweł , Grzywacz Anna , Wilk Aleksandra
Published: August 2020

E-cigarettes, a comparatively new phenomenon, are regarded as a safer alternative to conventional cigarettes. They are increasingly popular among adolescents of both sexes, and many smokers use e-cigarettes in their attempts to quit smoking. There is little understanding of the effects of exposure to e-cigarette vapors on human reproductive health, human development, or the functioning of the organs of the male and female reproductive systems. Data on the effects of the exposure were derived mainly from animal studies, and they show that e-cigarettes can affect fertility. Here, we review recent studies on the effects of exposure to e-cigarettes on facets of morphology and function in the male and female reproductive organs. E-cigarettes, even those which are nicotine-free, contain many harmful substances, including endocrine disruptors, which disturb hormonal balance and morphology and the function of the reproductive organs. E-cigarettes cannot be considered a completely healthy alternative to smoking. As is true for smoking, deleterious effects on the human reproductive system from vaping are likely, from the limited evidence to date.
Spillovers from the Slowdown in China on Financial and Energy Markets: An Application of VAR–VECH–TARCH Models
Authors: Özdurak Caner , Ulusoy Veysel
Published: August 2020

The 2008 global financial crisis provides us with a wide range of study fields on cross-asset contagion mechanisms in the US financial markets. After a decade of the so-called subprime crisis, the impact of market news on asset volatilities increased significantly. Consequently, return and volatility spillovers became the most extensive channel for spreading out the news generated in one market to the other ones, which made the financial markets inherit international risk factors as their own local risks. Moreover, as a result of the Chinese economy becoming the main driver of the global economy in the last decade, Chinese markets became more interconnected with developed markets which were followed by a “digital cold war” era via Twitter. In this study, we investigate the relationship between the US stock market, Chinese stock markets, rare earth markets and industrial metals, and mining products via three different models by utilizing VAR–VECH–TARCH models. According to our findings, bilateral spillover exists between US and Chinese stock markets. Cross-market spillovers show that there is a risk transmission channel between the industrial metals, rare earth, and Chinese and US stock markets due to China’s strengthening position in the global economy.
Tools for BIM-GIS Integration (IFC Georeferencing and Conversions): Results from the GeoBIM Benchmark 2019
Authors: Noardo Francesca , Harrie Lars , Arroyo Ohori Ken , Biljecki Filip , Ellul Claire , Krijnen Thomas , Eriksson Helen , Guler Dogus , Hintz Dean , Jadidi Mojgan , Pla Maria , Sanchez Santi , Soini Ville-Pekka , Stouffs Rudi , Tekavec Jernej , Stoter Jantien
Published: August 2020

The integration of 3D city models with Building Information Models (BIM), coined as GeoBIM, facilitates improved data support to several applications, e.g., 3D map updates, building permits issuing, detailed city analysis, infrastructure design, context-based building design, to name a few. To solve the integration, several issues need to be tackled and solved, i.e., harmonization of features, interoperability, format conversions, integration of procedures. The GeoBIM benchmark 2019, funded by ISPRS and EuroSDR, evaluated the state of implementation of tools addressing some of those issues. In particular, in the part of the benchmark described in this paper, the application of georeferencing to Industry Foundation Classes (IFC) models and making consistent conversions between 3D city models and BIM are investigated, considering the OGC CityGML and buildingSMART IFC as reference standards. In the benchmark, sample datasets in the two reference standards were provided. External volunteers were asked to describe and test georeferencing procedures for IFC models and conversion tools between CityGML and IFC. From the analysis of the delivered answers and processed datasets, it was possible to notice that while there are tools and procedures available to support georeferencing and data conversion, comprehensive definition of the requirements, clear rules to perform such two tasks, as well as solid technological solutions implementing them, are still lacking in functionalities. Those specific issues can be a sensible starting point for planning the next GeoBIM integration agendas.
Semantic Integration of Raster Data for Earth Observation: An RDF Dataset of Territorial Unit Versions with their Land Cover
Authors: Tran Ba-Huy , Aussenac-Gilles Nathalie , Comparot Catherine , Trojahn Cassia
Published: August 2020

Semantic technologies are at the core of Earth Observation (EO) data integration, by providing an infrastructure based on RDF representation and ontologies. Because many EO data come in raster files, this paper addresses the integration of data calculated from rasters as a way of qualifying geographic units through their spatio-temporal features. We propose (i) a modular ontology that contributes to the semantic and homogeneous description of spatio-temporal data to qualify predefined areas; (ii) a Semantic Extraction, Transformation, and Load (ETL) process, allowing us to extract data from rasters and to link them to the corresponding spatio-temporal units and features; and (iii) a resulting dataset that is published as an RDF triplestore, exposed through a SPARQL endpoint, and exploited by a semantic interface. We illustrate the integration process with raster files providing the land cover of a specific French winery geographic area, its administrative units, and their land registers over different periods. The results have been evaluated with regards to three use-cases exploiting these EO data: integration of time series observations; EO process guidance; and data cross-comparison.
OSMWatchman: Learning How to Detect Vandalized Contributions in OSM Using a Random Forest Classifier
Authors: Truong Quy , Touya Guillaume , Runz Cyril
Published: August 2020

Though Volunteered Geographic Information (VGI) has the advantage of providing free open spatial data, it is prone to vandalism, which may heavily decrease the quality of these data. Therefore, detecting vandalism in VGI may constitute a first way of assessing the data in order to improve their quality. This article explores the ability of supervised machine learning approaches to detect vandalism in OpenStreetMap (OSM) in an automated way. For this purpose, our work includes the construction of a corpus of vandalism data, given that no OSM vandalism corpus is available so far. Then, we investigate the ability of random forest methods to detect vandalism on the created corpus. Experimental results show that random forest classifiers perform well in detecting vandalism in the same geographical regions that were used for training the model and has more issues with vandalism detection in “unfamiliar regions”.
An Approach to Decompose and Evaluate a Complex GIS-Application Design to a Simple, Lightweight, User-Centered App-Based Design Using User Experience Evaluation
Authors: Kammerhofer David , Scholz Johannes
Published: August 2020

Working with contemporary, monolithic desktop Geographical Information Systems can be laborious and confusing, especially for non-experts. An alternative for a more user friendly approach to spatial data edition and spatial analysis may be an “app-based” web application that is offering single tasks for the user—“micro applications”. In this paper, a method for determining such “micro applications” based on user stories is presented and applied to a specific use case—the case is centered around an Austrian Governmental Institution that digitizes and edits infrastructure data. The results of this process are implemented in an app-based web application. To measure the impacts of the app-based approach, we evaluate the user experience of the app-based approach in comparison to a desktop Geographical Information System offering the same functionality. For the measurement of the user experience, we used a focus group. The group had to accomplish tasks with the desktop Geographical Information System and with the app-based web application. To measure their user experience, we employed the tool AttrakDiff. The app-based web application achieves significantly better results in terms of user experience. This result is confirmed in a discussion panel carried out afterwards. Test persons responded that positive aspects of the app-based web application were the easy and intuitive handling and reduced user interface that helps the users to focus on their tasks without any distraction.