bluuebunny/crossref_metadata_2025 huggingface dataset:
Steps to Create FASTQ of CCS Overlapping Genomic SSR - CCS ROI v5
Authors: P Harhay Gregory
Published: November 2019

The virulence and pathogenicity of bacterial pathogens are related to their adaptability to changing environments. Oneprocess enabling adaptation is based on minor changes in genome sequence, as small as a few base pairs, within segments of genome called simple sequence repeats (SSRs) that consist of multiple copies of a short sequence (from one to several nucleotides), repeated in series. SSRsare found in eukaryotesas well as prokaryotes, and variation in them occurs at frequencies up to a million-fold higher than the average bacterial mutation rate through a process of slipped stranded mispairing (SSM) by DNA polymerase during replication. The characterization of SSR length by standard sequencing methods is complicated by the appearance of length variation introduced during the sequencing process that does not accurately quantify lower-abundance repeat number variants in a population. Here we report a computational approach to correct for process-induced artifacts, validated for tetranucleotide repeats by use of synthetic constructs of fixed, known length. We apply this method to a laboratory culture ofHistophilus somni, prepared from a single colony, and demonstrate that the culture consists of populations of distinct sequence phase and read length variants at individual tetranucleotide SSR loci. Input requirements: Closed Genome - It is recommended that only organisms with closed genomes be the subject of the analyses described here. Mapping repetitive reads to to contigs of non-closed genomes may map to multiple locations, complicating tha analysis. Mapping CCS (circular consensus sequence) wiith repetitve sequence to closed genomes are guaranted to map to a single locus if sufficent unique flanking sequence is used to confim the unique mapping. Consequently, long CCS with high base quality are the most desirable input into this workflow.
Ultrasound evaluation of maternal visceral fat: New outcome marker during pregnancy? v1
Authors: Antonio Azevedo Magalhaes Jose , Mattos Salete , Cortes Kretzer Daniela , Rombaldi Bernardi Juliana , Rocha Alexandre
Published: November 2019

Quantification of visceral fat by ultrasound during pregnancy has been occupying a prominent role in the medical literature, since it does not use ionizing radiation present in tomography, the high cost of nuclear magnetic resonance imaging in addition to the ineffectiveness of body mass index measuring during pregnancy, as indicator of the quantity of accumulated visceral fat. Different ultrasound measurements on the abdomen have been proposed as indicators of the amount of visceral fat. A major example is the Armellini method, which measures at the level of xipho-pubic line with the transducer positioned one centimeter above the umbilical scar and the measurement have to be made from the internal edge of the linea alba, or inner side of the abdominal rectus muscles, until the anterior aortic wall. The measurement of maternal Armellini space will be according the proposal at study of Martin AM et.al (Martin AM, Berger H, Nisenbaum R et al. Abdominal visceral adiposity in the first trimester predicts glucose intolerance in later pregnancy. Diabetes Care 2009;32:1308-1310) using convex probe placed 1cm above the maternal umbilical scar at median sagittal plane position, and using electronic calipers to measure the distance from linea alba to aortic crossa. The final measurement was achieved by the mean measurement among maternal breath cicle at inspiration and expiration.
Features of the Metallization Influence on Phase Velocities of Acoustic Waves in Piezoelectric Plates
Authors: Zolotova Olga P. , Burkov Sergey I.
Published: November 2019

The paper presents an analysis of the influence of the load represented by two metal layers on the change in the phase velocity of the dispersion modes of the elastic Lamb and SH-waves in "Me/ZnO/Me" and "Me/AlN/Me" structures depending on the elastic wave frequency and the ratio of the metal layer to the piezoelectric layer thickness. Aluminum (Al), molybdenum (Mo) and platinum (Pt) are considered as the metal layer materials (Me). Only the elastic Lamb wave modes have localized maxima of the sensitivity curve S for all types of structures. Systems with low values of acoustic impedances for layers and plates materials have maximum values of S for metallization with thin layers, and also have minimal differences in the profiles of the components of the displacement vectors of the elastic wave. Systems with the most different values of acoustic impedances of layers and plates materials have maximum values of S when metallized with thick layers, and also have maximum differences in the profiles of the components of the displacement vectors of the elastic wave. PACS: 43.25.Fe; 43.35.Cg; 77.65.-j
The relationship between sexuality and temperament in patients with epilepsy
Authors: Sosnina V. G. , Saraykin D. M. , Lipatova L. V.
Published: November 2019

Aim: to study the relationship between sexuality and temperament in patients with epilepsy.

Materials and methods. The study included 102 participants: 52 patients with epilepsy and 50 healthy individuals aged from 19 to 45 years. The psychological examination was based on the I-structural test of Ammon (ISTA), the Structure of temperament questionnaire (STQ) of Rusalov, and a clinical interview.

Results. Using the correlation analysis we were able to reveal 9 correlations between the types of sexuality and the temperament characteristics in patients with epilepsy; in subjects of the control group – 4 correlations were found. Thus, in patients with epilepsy, constructive sexuality positively correlated with plasticity, social erginess, and pace, whereas in healthy subjects – with social erginess. In patients with epilepsy, destructive sexuality positively correlated with plasticity, social erginess, and social plasticity; in healthy subjects, destructive sexuality negatively correlated with social erginess. In patients with epilepsy, deficient sexuality negatively correlated with pace, plasticity, and social erginess, whereas in healthy subjects – with plasticity and social plasticity.

Conclusion. The study shows that the sexuality in patients with epilepsy is more deterministic than that in the comparison group. In addition, all types of sexuality in these patients correlate with plasticity and social erginess, which suggests that patients with epilepsy can be satisfied with sexual relations, show flexibility and strive for diversity while being flexible and socially active. These correlations can be read vice versa, i.e., striving for diversity and social activity in patients with epilepsy is accompanied by satisfaction with their sexual relations and inclination to experiment.
TRENDS IN THE MODERNIZATION OF THE CRIMINAL LAW RESPONSE TO DRUG CRIME
Authors: Dziadkouski Andrei
Published: November 2019

The paper deals with the problem of countering the illicit drug trafficking, psychotropic substances, their precursors and analogues in the Eurasian Economic Union countries. The authors, basing on the statistical data analysis, demonstrated an increase in the number of drug addicts; it is shown that drug addiction is a global problem nowadays. The constant   increase of registered criminal acts related to drugs and their cross-border nature make it necessary to develop cooperation in combating the illicit distribution of drugs, harmonizing and unifying legal norms in this area, especially within the framework of the Eurasian Economic Union. A comparative legal analysis of the criminal law governing liability for drug trafficking in the EAEU countries shows the diversity of legislative structures in the key elements of the crimes under consideration. The issues of personal non-medical use liability, the subject of crimes, the criminalization of individual acts related to drug trafficking, should be the subject of discussion on developing a unified approach of criminal law to counter the analyzed crimes in the EAEU countries.
DEVELOPMENT OF UNIFIED PROCEDURES FOR FINANCIAL INSTITUTIONS IN ORDER TO PREVENT MONEY LAUNDERING AND TERRORISM FINANCING
Authors: Kalinina Suzanna
Published: November 2019

The relevance of the topic is confirmed by the changes taking place in the financial monitoring system: the expansion of the financial monitoring range of procedures complication´s supervisory bodies aimed at countering money laundering and financing of terrorism, the creation of specialized international and European requirements, which causes changes in the legal regulation of public relations in this area, both at the level of the Estonian Republic, and at international level. Taking into account these changes, financial institutions are a subject to significant legal risks. The purpose of this topic is to improve the financial institution risk management system, in the field of anti-money laundering and countering financing of terrorism. The theoretical and methodological basis of the study are the provisions and conclusions regarding anti-money laundering and countering financing of terrorism risk management issues contained in the research works of different Estonian and Russian authors; as well as the author analysed anti money laundering and counter terrorism financing legal acts and revealed the main recommendations to financial institutions for preventing money laundering and terrorism financing.  The author analyses reasons, which affect licenses withdrawal due to breach of money laundering. The nature of the tasks and the system approach to their solution determined the use of the following research methods in the research: analysis and synthesis, grouping and classification, scientific generalization, expert assessments and graphical analysis.
Earthquake Rupture Scaling Relations for Mainland China
Authors: Cheng Jia , Rong Yufang , Magistrale Harold , Chen Guihua , Xu Xiwei
Published: November 2019

Magnitude‐rupture scaling relations describe how the length, width, and area of fault rupture vary with earthquake magnitude. These parameters are required in seismic hazard models to fit the models’ earthquakes onto faults and to define the site‐rupture distances needed in ground‐motion prediction equations. We collected the magnitude and rupture parameters of 91 earthquakes in Mainland China and nearby regions to study magnitude‐rupture scaling relations. We find no systematic deviations for the subsurface rupture length (RLD) obtained from different methods versus earthquake magnitude. We performed regressions of RLD versus magnitude and versus rupture width using general orthogonal regression. Then, we derived the relations between rupture area and magnitude. Our relations are not statistically different from the results derived by others using global datasets, if the parameters of the five pre‐1900 great earthquakes in eastern China are not used. However, if the five earthquakes are used, the magnitude‐rupture length scaling relation for large strike‐slip earthquakes in eastern China gives shorter rupture lengths than earthquakes in western China and other plate boundary regions in the world.
Mirada a las Potestades Que Otorga el Derecho de Propiedad Industrial - Derecho de Patente
Authors: Mercado Amaris Luzney , Olivares Álvarez Dayana
Published: November 2019

La propiedad privada dicha en pocas palabras es; el derecho a proteger lo que es de uno, y el Estado nos brinda leyes civiles y comerciales para ello. En la rama del derecho comercial encontramos derechos sobre cierta propiedad privada con unos elementos particulares; la propiedad intelectual la cual le pertenece al individuo no solo por ser reclamada por él, sino porque emerge de su imaginación o intelecto, esa es su particularidad, las potestades que este derechos brinda, abarca gran parte de las relaciones comerciales, industriales, artísticas y culturales, sin embargo para el presente estudio solo será objeto central las patentes derivadas de la propiedad industrial, para entrar en materia es necesario dar a entender que es la propiedad industrial y como está compuesta.
Deber De Los Deberes
Authors: Cabarcas Muñiz Juan Carlos
Published: November 2019

Siempre he sostenido, contrario a cuanto enseña la Constitución que son los jueces de la República quienes ejercen la acción Penal, quienes la ejercitan verdaderamente, de manera soberana. La autonomía se la dejamos a los señores Fiscales. Esa autonomía débil y vulnerable frente al señor Fiscal General de la Nación que, a la postre es el único autónomo y dentro de esa autonomía omnímoda y poderosa tiene sus delegados en todo el territorio patrio que tienen el derecho de obedecerle y el deber de seguir sus instrucciones, recomendaciones y sugerencias jurídicos – procesales.
Puntos Críticos de las Principales Vías Terrestres de Cartagena y su Incidencia en la Movilidad Para la Búsqueda de una Ciudad Inteligente
Authors: Boyano Fram Teófilo Omar
Published: November 2019

La ciudad de Cartagena ha ido creciendo en los últimos años por diferentes razones, entre las que se destaca la oportunidad de empleo en el sector turístico, ya sea de manera formal o informal, los más destacados son el sector petroquímico y el logístico portuario. Dada la gran importancia de las ciudades sostenibles y de acuerdo a las ODS declaradas por la ONU, dentro de la sostenibilidad está la calidad de vida y una de sus principales preocupaciones está en la movilidad. Con el siguiente artículo se trata de ilustrar los puntos críticos en materia de movilidad relacionado con la infraestructura vial y por lo tanto terrestre en la ciudad de Cartagena en el año 2018, con la finalidad de que se tomen medidas y que sirva como elemento de estudio para futuros investigadores.
Consejos de Papá
Authors: Goyeneche Fredy Eduardo
Published: November 2019

Camina por el lado opuesto de las angustias, desplaza tus pasos un tanto al centro pero mantén el equilibrio, que el lado izquierdo cercano al corazón sepa que hace tu mano derecha de acciones diversas. No te distraigas con mariposas amarillas, ni escuches la última  campanada ni el tercer canto de gallos de falsas madrugadas. Los ladrones de destinos acecharán para la primera dentellada cuando te muestren el oropel de las fantasías de mala ley y peores premoniciones de recuerdos vacíos...
Inmaculada
Authors: Barrios Díaz Johely
Published: November 2019

Me contempla incesante, plácida, reduciendo mi coraje a un pánico bélico, retumbante, un patético sentimiento cuyo ser me entumecía, solía ser cuán destello del cosmos abraza el alma hundiéndole astral, procurando quebrarle sutil e inocentemente el deseo de fugarse...
Concept of clinical pharmacology and therapeutics sensitization and training for interns
Authors: Dixit Rohit , Joshi K. P.
Published: November 2019

Background: Rational prescribing of the medicines is an essential skill required by all the doctors. Interns are not prepared or confident in rational prescription either because of inadequate training or knowledge is not retained by the time they come to internship or due to fast change in the concepts or protocols in pharmacology. The objectives of the study were to introduce and assess a short sensitization and training for interns regarding clinical pharmacology and therapeutics (CPT).Methods: It was a quasi-experimental type of interventional study done on 30 pediatrics interns. A short sensitization and training was given regarding CPT using flipped classroom model. Pre-test and post-test was conducted to know the effectiveness of the sensitization/training. Students’ opinion was also taken regarding the training and incorporation of similar training in other departments.Results: The mean percentage scores of the objective type questions in the pretest was 40.6±3.25 which increased significantly (p<0.05) to 74±2.95 in post-test. The mean percentage scores of the problem solving type questions in the pretest was 30.78±5.25 which increased significantly (p<0.05) to 65.21±4.65 in post-test.Conclusions: The sensitization and training was effective and there was overall satisfaction of conduct of such training among pediatrics interns. Further detailed research has to be conducted in different departments and faculties’ opinion regarding incorporation of CPT training and feasibility has to be considered before we recommend such training during internship.
PERCEPÇÕES E DESAFIOS DA EQUIPE DE ENFERMAGEM FRENTE À HOSPITALIZAÇÃO DE CRIANÇAS COM TRANSTORNOS AUTÍSTICOS
Authors: De Oliveira Ana Carolina Araújo , De Morais Rita de Cássia Melão , Franzoi Mariana André Honorato
Published: November 2019

Objetivo: analisar as percepções e os desafios da equipe de enfermagem relacionados à assistência voltada a crianças hospitalizadas com Transtornos do Espectro do Autismo. Método: estudo descritivo, exploratório, de abordagem qualitativa realizado com 19 profissionais de enfermagem da Clínica Pediátrica de um Hospital de Ensino do Distrito Federal, Brasil. A coleta de dados ocorreu no período de setembro a dezembro de 2017, por meio de entrevistas semiestruturadas que, após transcrição, foram submetidas à análise de conteúdo temática. Resultados: desvelaram-se as seguintes categorias: Vivências no cuidado à criança com Transtornos do Espectro do Autismo; e Desafios para a melhoria da assistência a crianças hospitalizadas com Transtornos do Espectro do Autismo. Conclusão: os profissionais da equipe de enfermagem sentem-se inseguros e despreparados durante a assistência, devido à incipiência de conhecimento, o que gera uma dependência da família, para mediar o cuidado da criança com transtornos autísticos hospitalizada.

Descritores: Criança Hospitalizada. Transtorno Autístico. Equipe de Enfermagem.
CONVIVÊNCIA COM FILHOS COM TRANSTORNO DO ESPECTRO AUTISTA: DESVELANDO SENTIDOS DO SER-AÍ-MÃE
Authors: Rendon Daniela De Cássia Sabará , Salimena Anna Maria De Oliveira , Amorim Thaís Vasconselos , Paiva Andyara Do Carmo Pinto Coelho , Melo Maria Carmen Simões Cardoso de , Batista Bárbara Lacy Vitorino
Published: November 2019

Objetivo: desvelar sentidos de mães na convivência com filhos acometidos pelo transtorno de espectro autista (TEA). Método: pesquisa qualitativa, ancorada na fenomenologia heideggeriana, com dados coletados por meio de entrevista fenomenológica com 14 mulheres/mães, entre janeiro e março de 2016. Resultados: as mães significaram que a convivência trazia aprendizado, mudanças como ser humano e busca por saber tudo a respeito de autismo; e não conseguir trabalhar, por ter de cuidar do filho, sentir-se excluída e sobrecarregada. Conclusão: o alcance do movimento existencial do ser-aí-mãe na convivência com o filho acometido pelo TEA permitiu compreender as mudanças, exigências e cobranças que cabiam à mulher que, de modo inautêntico, ocupava-se com a rotina de cuidados ao filho. Preocupando-se em oferecer o melhor de si, sentia-se distante do cuidado consigo e com suas relações sociais e familiares. Do mesmo modo, pela fragilidade da rede de apoio social, tornava-se vulnerável biopsicosocioespiritualmente.

Descritores: Transtorno Autístico. Relações Mãe-Filho. Cuidados de Enfermagem.
INVESTIGATING THE USE OF CIGARETTE, ALCOHOL, AND DRUG IN STUDENTS AND FACTORS AFFECTING IT
Authors: Rahmati Robab , Amirfakhraei Azita , Karemafshar Eshrat
Published: November 2019

Purpose: Increasing the use of cigarettes, drug and alcohol in adolescents have nowadays become a serious challenge in communities. Thus, the present study was conducted to investigate the use of drugs, cigarettes, and alcohol and factors affecting adolescents.

Methodology: The research method was a cross-sectional survey study. The research population included all of the second-grade high school students in the Tehran province cities. Using random cluster sampling method, 448 of them were selected and responded to the test questions. 

Result: The research results showed that boys used hubble-bubble (0.88), alcohol (0.51), cigarette (0.39), psychotropic pills (21) and girls used hubble-bubble (0.79), alcohol (0.29), and psychotropic pills (0.28) and cigarettes (0.17). The rate of using all drugs was higher in boys than that of girls. The use of hubble-bubble and alcohol had the highest rate and the use of heavier drugs was less prevalent. However, as the use of lighter drugs predisposed one person to use other drugs, taking preventive measures in schools and at an early age was essential.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of Investigating the Use of Cigarette, Alcohol, and Drug in Students and Factors Affecting it is presented in a comprehensive and complete manner.
ASSESSMENT MODEL OF QUALITY AND DEMAND FOR EDUCATIONAL SERVICES CONSIDERING THE CONSUMERS’ OPINION
Authors: A. G. Tyurikov , A. N. Zubets , P. V. Razov , A. N. Amerslanova , N. V. Savchenko
Published: November 2019

Purpose: The purpose of the article is to develop an integrative, structural and functional, indicative, aggregating, algorithmic, the multi-criteria model for assessing the quality and demand for educational services of higher education considering the consumers’ opinion.

Methodology: The leading research method of the indicated problem was the assessment of various aspects of educational relations in the process of complex diagnostics of the studied phenomena, which includes: preliminary system model of research, interpretation and operationalization of the basic concepts included in it; relevant means of fixation of primary characteristics; the order of data collection; algorithm of analysis and data processing in order to obtain a rating assessment proposed as a mechanism for assessing the quality and demand for educational services with the participation of consumers.

Result: The authors substantiate the inclusion in the system of indicators of both objective characteristics: the professional status of graduates of higher educational institutions (the share of employed, the level of wages, the area of employment), the status of educational programs (social and professional accreditation), and their subjective characteristics, expressed in: the formation of professional competencies of graduates (including hard skills and soft skills), which together characterize their professional subjectivity. The materials of the article are of practical value for government agencies, heads of educational institutions, rating agencies, representatives of organizations-employers, applicants, their parents, and students.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of Assessment model of quality and demand for educational services considering the consumers’ opinion is presented in a comprehensive and complete manner.
Method of Calculating Carbon Ablation in the Jet of Liquid Rocket Engine Combustion Products
Authors: Gorskiy V.V. , Kovalsky M.G. , Resh V.G.
Published: November 2019

Nowadays carbon materials are widely used as ablating thermal protection for high-temperature structural elements in aerospace technology. Prediction of changes in the shape of the external surfaces of these elements, due to the burning of thermal protection, is closely related to the use of computational-theoretical methods describing the flow of various physicochemical and mechanical processes associated with the occurrence of the phenomenon under consideration. At the same time, it is crucial to test such methods on the results of experimental studies conducted under conditions which are implemented during the process of testing thermal protection in jets of aerodynamic units. The main elements of ablation of carbon materials include their erosion, i.e., mechanical ablation of mass, observed in high-pressure gas flows. In the process of experimental development, it is necessary to carry out research on large-scale models, which has led to widespread use of underexpanded jets of combustion products of liquid rocket engine combustion products for modeling the erosion process of thermal protection. The theoretical model of ablation of thermal protection in such jets requires taking into account the complex chemical composition of the gas mixture flowing into the model; physical and chemical interaction of this gas with thermal protection, which causes gasification of the latter; use of mathematical models describing the process of material erosion due to mechanical impact of high-pressure gas flow. The paper describes the development of the carbon material ablation calculating and theoretical methodology which could be used to determine the material erosion characteristics on the basis of solving a complex problem of circumfluence, heating, heat penetration and ablation of thermal protection.
Problems of Parts Reliability in the Design of Mechanical System
Authors: Manshin Yu.P. , Manshina E.Yu.
Published: November 2019

The paper deals with the problems of rationing reliability indicators in the early stages of machine design, which allow the designer to develop the entire list of crucial parts in terms of reliability, and provide a given level of reliability. By analyzing the existing methods of rationing the reliability, we revealed their insufficiency for design, as well as contradictions associated with the use of the exponential law of reliability for this purpose. We synthesized an alternative approach to rationing, which makes it possible to perform a complete structural analysis of the project: from the reliability of the system as a whole to the parts, whose reliability determines the reliability of machines. At the structural level of parts and other elements whose failures are not sudden, the use of the exponential law is eliminated, but the inherent simplicity of mathematical operations is preserved.
Comparative Study of Ultrasonographic Features of Abomasum in Cattle and Buffaloes Suffering from Various Gastrointestinal Tract Disorders
Authors: Singh Sodhi Harmanpreet Kadir , Mohindroo Jitender , Mahajan Sashikant , Verma Pallavi , Singh Opinder
Published: November 2019

The present study was conducted on 40 clinical cases of bovine (10 cattle, 30 buffaloes) to ultrasonographically evaluate the position of abomasum in relation to anatomical landmarks in cattle and buffaloes suffering from various gastrointestinal tract (GIT) affections. Animals were divided into five groups viz. foreign body syndrome (n=14), faecolith (n=6), caecal impaction (n=5), reticular abscess (n=2) and diaphragmatic hernia (n=13) as per disease condition confirmed upon ultrasonography and surgical findings. Ultrasonographically, the distance from caudal most aspect of wither at dorsal spine to dorsal most aspect of abomasum, distance from xiphoid to cranial most aspect of abomasum, distance from mid of umblicus to caudal most aspect of abomasum and distance from ventral midline to ventral most aspect of abomasum was recorded to evaluate the size of abomasum. The ultrasonographic findings were correlated with intra-operative findings. It was concluded that the size of abomasum is significantly reduced in animals suffering from caecal impaction while the size of abomasum was significantly increased in animals suffering from faecolith and was comparable in animals suffering from diaphragmatic hernia, foreign body syndrome and reticular abscess. The location of pylorus was not significantly altered in any disease condition.
Genetic and Non-Genetic Factors Affecting Post-Weaning Growth and Morphometric Traits in Assam Hill Goat
Authors: Sarma L. , Nahardeka N , Aziz A. , Nahardeka N , Goswami R. N. , Zaman G. , Das A. , Akhtar F.
Published: November 2019

The present work was conducted to evaluate the performance in respect of post-weaning growth and morphometric traits of Assam Hill goat. Data on 960 animals belonging to 3 populations of Assam Hill goat maintained at three field units viz., Batabari, Nahira and Tetelia under All India Coordinated Research Project on Goat Improvement were utilized. The least-squares means for body weight, height at withers, heart girth and body length were 7.557 ± 0.049 kg, 41.231 ± 0.121 cm, 44.621 ± 0.115 cm and 50.778 ± 0.172 cm at 6 months; 9.934 ± 0.044 kg, 43.902 ± 0.120 cm, 48.890 ± 0.099 cm and 55.552 ± 0.170 cm at 9 months and 12.549 ± 0.046 kg, 46.791 ± 0.112 cm, 52.765 ± 0.090 cm and 58.392 ± 0.207 cm at 12 months of age, respectively. Location had significant effect on body weight and height at withers at all age groups; on heart girth at 6, 9 and 12 months and on body length at 6 and 12 months of age. Season of birth exerted significant effect on body weight at 9 and 12 months; on height at withers at 12 months and on body length at 6, 9 and 12 months of age. Significant effect of sex was observed on body weight at 9 and 12 months, on height at withers at 6, 9 and 12 months and on heart girth and body length at 9 and 12 months of age. The heritability estimates for body weight and body measurements were moderate indicating scope of selection. The phenotypic and genetic correlation among body weights and body measurements at 6, 9 and 12 months of age were positive in direction and high in magnitude.
Status of Oxidative Stress in Cerebral Cortex and Testes, Acetylcholinesterase Activity in Cerebral Cortex and Sperm Parameters in Cadmium-Exposed Rats
Authors: Makwana C. N , Rao S. S. , Patel U. D. , Modi C. M. , Patel H. B. , Fefar D. T.
Published: November 2019

The present study was carried out to evaluate oxidative stress mediated pathophysiological alterations in brain cerebral cortex and testes of rats exposed to cadmium chloride at 15, 50 and 100 ppm in drinking water for 28 days. The activity of SOD in brain of rats of all toxicity groups was non- significantly decreased. The SOD activity in testes was significantly decreased in animals exposed to 50 and 100 ppm level of cadmium. The catalase activity in brain cerebral cortex and testes was significantly decreased in dose dependent manner. The GSH levels in brain and testes tissue were increased at all tested levels of exposure of cadmium. The acetylcholinesterase activity in brain of rats exposed all levels of Cd were significantly decreased. Cadmium exposure at 100 ppm level significantly reduced the total epididymal sperm count. However, the epididymal sperm motility was significantly reduced in rats exposed to all tested levels of cadmium. The different levels of cadmium exposure produced pathological lesions in brain cerebral cortex and testes which were remarkable at 100 ppm level of exposure as compared to other levels of exposure in rats. In conclusion, cadmium exposure at 100 ppm for 28 days in rats produced marked alterations in both brain and testes through oxidative insult.
Exploration of RNA-Guided Recombinase Target Sites for Hyperactivated Recombinase Beta in Bovine Genome
Authors: Pathak Shalu Kumari , Sonwane Arvind , Kumar Subodh
Published: November 2019

The present study was conducted to determine the effect of different cooling systems; Fan Fogger (FF) and Fan Pad (FP) on micro environment of poultry house, thermal comfort, welfare, egg production and egg quality parameters of laying hens. This experiment was conducted on 210, White Leghorn laying pullets (32 weeks old) during hot-dry summer months (May - July) under deep litter system of housing. The FP and FF cooling systems significantly dropped the mean shed temperature and increased the relative humidity. Thus, better THI resulted in increase in egg production by 4.66 % and 3.32 % under FP and FF systems over the control group. However, specific gravity, H.U, egg shell thickness, yolk index and yolk color were not significantly influenced by cooling treatments. Significantly lower levels of antioxidant enzymes viz. LPO, Catalase, G6PD, GPx and SOD was registered in cooling groups. Both the cooling devices contributed towards bird welfare by altering the behavioral expression from agonistic to non-agonistic activities.RNA-guided recombinases (RGR) are potentially valuable tools for basic research and genetic modifications. The platform has been demonstrated to do genome editing efficiently. The platform operates on a typical recognition site comprised of the degenerate recombinase site, a 5 to 6-base pair spacer flanking it and this whole central region is flanked by two guide RNA-specified DNA sequences or Cas9 binding sites which is followed by protospacer adjacent motifs. In present investigation, a detailed map of target sites for RNA-guided recombinase platforms based on hyperactivated recombinase Beta throughout the bovine genome was prepared. For this, Chromosome wise whole genomic sequence data was retrieved from Ensembl followed by designing search pattern for recombinase Beta with spacer length five. By using this search pattern, RGR target sites were located by using dreg program of Emboss package. In total,436 RGR target sites were identified in bovine genome for recombinase Beta with spacer length five. These RGR target site provide potential of being utilized for specific genomic integration, deletion or inversion.
La pasarela de los dioses. El Zeus de Olimpia y el Coloso de Rodas como modelos iconográficos divinos en el cristianismo = The Catwalk of the gods. The Olympian Zeus and the Colossus of Rhodes as divine iconographic models in Christianity
Authors: Miguel Irureta Ainhoa de , Carbó García Juan Ramón
Published: November 2019

Resumen: La estatua de Zeus en Olimpia realizada por Fidias y la estatua colosal de Helios en Rodas realizada por Cares de Lindos, dos de las 7 maravillas de la Antigüedad y las únicas de carácter escultórico, se convirtieron en modelos iconográficos de poder, de majestad y de lo colosal para emperadores, abstracciones personificadas y también para otros dioses. A través del análisis de estas maravillas, de sus ropajes, atributos, complementos, posturas, tamaño, etc. y de cómo fueron asumidos o cómo influyeron posteriormente tanto para las imágenes del Dios cristiano como para la de emperadores romanos cristianos y emperadores posteriores, pretendemos poner de manifiesto la gran relevancia e influencia religiosa de las representaciones más paradigmáticas de estos dioses a lo largo de dos mil años, gracias a haber “desfilado” en esas pasarelas privilegiadas que constituyeron las diferentes listas de las 7 maravillas del mundo antiguo.Abstract: The statue of Zeus at Olympia by Phidias and the colossal statue of Helios at Rhodes by Chares of Lindos, two of the 7 Wonders of Antiquity and the only ones of sculptural character, became iconographic models of power, majesty and the colossal for emperors, for personified abstractions as well as for other gods. We intend to highlight the great relevance and religious influence of the most paradigmatic representations of these gods over two thousand years, thanks to having paraded in those privileged catwalks that constituted the different lists of the 7 Wonders of the ancient world. And we will do it through the analysis of these wonders, its size, clothes, accessories, positions, attributes… and how they were taken or how they influenced the images of the Christian God and the Christian Roman Emperors and later Emperors.Palabras clave: Zeus, Coloso de Rodas, Siete Maravillas, iconografía, Cristo, modelos, atributos.Key words: Zeus, Colossus of Rhodes, Seven Wonders, iconography, Christ, models, attributes
Klostergaard Petersen, Anders y Kooten, George van (eds): Religio-philosophical discourses in the Mediterranean World: From Plato, through Jesus, to Late Antiquity. Ancient philosophy and religion, 1., Leiden-Boston: Brill, 2017
Authors: Hernández de la Fuente David
Published: November 2019

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Wittgenstein and Modernism: an encounter of the third kind = Wittgenstein y el modernismo: un encuentro en la tercera fase
Authors: Matar Anat
Published: November 2019

Abstract: In earlier works, the author has twice discussed Wittgenstein’s work in relation to the modernist Geist that prevailed during his time. In the first, it was argued that the Tractatus was a modernist cornerstone, and then the idea was advanced that Wittgenstein’s later thought exemplified an essential modernist trait. Without contradicting these claims, a criticism is now offered on the aestheticism crucial to modernism and also to Wittgenstein’s thought.Key words: Wittgenstein, modernism, Tractatus, criticism, Aesthetics.Resumen: En el pasado, dos veces trabajé discutiendo sobre el trabajo de Wittgenstein en relación con el Geist que prevalecía en su época. Argüí, primero, que el Tractatus era una piedra angular y entonces continué la idea de que el último pensamiento de Wittgenstein ejemplificaba un esencial tratado modernista. Sin contradecir estos propósitos, ofrezco ahora una visión crítica del esteticismo crucial para el Modernismo y también para el pensamiento de Wittgenstein.Palabras clave: Wittgenstein, Modernismo, Tractatus, teoría crítica, estética.
Cartografía e Imperio. El Padrón Real y la representación del Nuevo Mundo
Authors: Manso Porto Carmen
Published: November 2019

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StEMORS: A Stochastic Eco-Hydrological Model for Optimal Reservoir Sizing
Authors: Koskinas Aristotelis , Tsira Pinelopi , Tegos Aristoteles
Published: November 2019

Dams design and their operation cause strong environmental alteration and therefore a long-term debate is ongoing for the scale of these projects. At the same time, the concept of Environmental Flow Assessment (EFA) is a crucial element of modified ecosystems featuring large infrastructure such as dams and reservoirs for mitigating potential environmental degradation while they operate. Nowadays, integrated scientific frameworks are required to quantify the risks caused by large infrastructure. Through the use of stochastic analysis, it is possible to quantify these uncertainties, and present a solution that incorporates long-term persistence and environmental sustainability into a balanced reservoir simulation model. In this work, an attempt is made to determine a benchmark reservoir size incorporating hydrological and ecological criteria though stochastic analysis. The primary goal is to ensure the best possible conditions for the ecosystem, and then secondarily to allow a steady supply of water for other uses. Using a synthetic timeseries based on historical inputs, it is possible to determine and preserve essential statistical characteristics of a river’s streamflow, and use these to detect the optimal reservoir capacity that maximizes environmental and local water demand reliability.
Radiation Induced Transient Currents in Films of Poly(Arylene Ether Ketone) Including Phthalide Moiety
Authors: Pozhidaev Evgenii , Shaposhnikova Vera , Tameev Aleksey , Abrameshin Andrey
Published: November 2019

Electrical properties of the thin films of poly(arylene ether ketone) copolymers (co-PAEKs) with the fraction of phthalide-containing units of 3, 5 and 50 mol% in the main chain were investigated by using radiation induced conductivity (RIC) measurements. Transient current signals and current-voltage (I-V) characteristics were obtained under exposing 20÷25 thick films of the co-PAEKs to monoenergetic electron pulses of the energy ranged from 3 to 50 keV in the electric field ranged from 5 to 40 V/μm. The Rose-Fowler-Vaisberg semi-empirical model based on a multiple trapping formalism was used for an analysis of the RIC data and the parameters of the highly dispersive charge carrier transport were evaluated. The analysis revealed that charge carriers moved in isolation from each other and the applied electric fields were below the threshold field triggering the switching effect (a reversible high-to-low resistivity transition) in the co-PAEK films. It was also found that the co-PAEK films due to the super-linear I-V characteristics are highly resistant to electrostatic discharges arising from the effects of ionizing radiation. This property is important for the development of protective coatings for electronic devices.
An All-Weather Land Surface Temperature Product Based on MSG/SEVIRI Observations
Authors: Martins Joao Paulo A. , Trigo Isabel , Ghilain Nicolas , Jimenez Carlos , Goettsche Frank-M. , Ermida Sofia L. , Olesen Folke , Gellens-Meulenberghs Françoise , Arboleda Alirio
Published: November 2019

An all-weather land surface temperature (LST) product derived at the Satellite Application Facility on Land Surface Analysis (LSA-SAF) is presented. The product is based on clear-sky LST retrieved from MSG/SEVIRI infrared (IR) measurements, complemented by LST estimated with a land surface energy balance (EB) model to fill gaps caused by clouds. The EB model solves the surface energy balance mostly using products derived at LSA-SAF. The new product is compared with in situ observations made at 3 dedicated validation stations, and with a Microwave (MW) based LST product derived from AMSR-E measurements. The validation against in-situ LST indicates an accuracy of the new product between -0.8 K and 1.1 K and a precision between 1.0 K and 1.4 K, generally showing a better performance than the MW product. The EB model shows some limitations concerning the representation of the LST diurnal cycle. Comparisons with MW LST generally show higher LST of the new product over desert areas, and lower LST over tropical regions. Several other imagers provide suitable measurements for implementing the proposed methodology, which offers the potential to obtain a global, nearly gap-free LST product.
Design and Optimization of Cost-Effective Coldproof Portable Enclosures for Polar Environment
Authors: Parsi Behzad , Zhang Lihong
Published: November 2019

Based on the International Electrotechnical Commission (IEC) standards, the electronic devices in the industrial class (e.g., integrated circuits (ICs) or batteries) can only operate at the ambient temperature between -40°C and 85°C. For the human-involved regions in Alaska, Northern Canada, and Antarctica, extreme cold condition as low as -55°C might affect sensing electronic devices utilized in the scientific or industrial applications. In this paper, we propose a design and optimization methodology for the self-heating portable enclosures, which can warm up the inner space from -55°C for encasing the low-cost industrial-class electronic devices instead of expensive military-class ones to work reliably within their allowed operating temperature limit. By considering various factors (including hardness, thermal conductivity, cost, and lifetime), we determine to mainly use polycarbonate as the manufacturing material of the enclosure. Among the other options, ceramic thermal resistors are selected as the heating elements inside the enclosure. The placement of the thermal resistors is studied with the aid of thermal modelling for the single heating device by using the curve fitting technique to achieve uniform temperature distribution within the enclosure. To maintain the inner temperature above -40°C but with the least power consumption from the thermal resistors, we have developed a control system based on the fuzzy logic controller (FLC). For validation, we have first utilized COMSOL Multiphysics software and then prototyped one enclosure along with the control system. Our experimental measurement exhibits its efficacy compared to the other design options.
Genome-Wide Analysis of Whole Human Glycoside Hydrolases by Data-Driven Analysis in Silico
Authors: Nakamura Takahiro , Fahmi Muhamad , Tanaka Jun , Seki Kaito , Kubota Yukihiro , Ito Masahiro
Published: November 2019

Glycans are involved in various metabolic processes via the functions of glycosyltransferases and glycoside hydrolases. Analysing the evolution of these enzymes is essential for improving the understanding of glycan metabolism and function. Based on our previous study of glycosyltransferases, we performed a genome-wide analysis of whole human glycoside hydrolases using the UniProt, BRENDA, CAZy, and KEGG databases. Using cluster analysis, 319 human glycoside hydrolases were classified into four clusters based on their similarity to enzymes conserved in chordates or metazoans (Class 1), metazoans (Class 2), metazoans and plants (Class 3), and eukaryotes (Class 4). The eukaryote and metazoan clusters included N- and O-glycoside hydrolases, respectively. The significant abundance of disordered regions within the most conserved cluster indicated a role for disordered regions in the evolution of glycoside hydrolases. These results suggest that the biological diversity of multicellular organisms is related to the acquisition of N- and O-linked glycans.
Karakterisasi Bakteri Endofit Kitinolitik sebagai Agens Biokontrol Patogen Ganoderma boninense pada Kelapa Sawit [Characterization of Chitinolytic Endophyte Bacteria as Biocontrol Agents of Ganoderma boninense Pathogen on Oil Palm]
Authors: Rahma Rahma , Kuswinanti Tutik , Rosmana Ade
Published: November 2019

Basal stem rot caused by Ganoderma boninense is one crucial disease in oil palm. The used of chitinolytic bacteria is one part of biological control to suppress G. boninense. This study aimed to isolate and characterize chitinolytic bacteria associated with roots of oil palm which have the potential as agents biocontrol against the pathogens of G. boninense, the caused of basal stem rot disease of oil palm. The study was conducted in North Luwu, East Luwu, and Makassar Districts from January to September 2017. The research was done in  four stages that consist of isolation of endophytic bacterial, testing chitinolytic activity, testing antagonistic and biochemical identification. The results showed that from 14 bacterial isolates obtained, two of them had chitinolytic activity with index of 2,35 and 3,37 respectively. Both of these bacteria can inhibit G. boninense on solid medium by 24,9% and 69,4% respectively and on the liquid medium by 47,5% and 68,5% respectively five days after inoculation. Based on biochemical characterization, these bacteria have similarities with Bacillus sp, and Serratia sp. To be concluded, Serratiasp. is a potential medium to be for controling basal stem rot disease on oil palm.

ABSTRAK
Busuk pangkal batang yang disebabkan oleh cendawan Ganoderma boninense merupakan salah satu penyakit penting pada kelapa sawit. Pemanfaatan bakteri kitinolitik merupakan salah satu bagian pengendalian hayati untuk mengontrol G. boninense. Penelitian ini bertujuan untuk mengisolasi dan mengkarakterisasi bakteri kitinolitik yang berasosiasi dengan akar tanaman kelapa sawit yang berpotensi sebagai agens biokontrol terhadap G. boninense, penyebab penyakit busuk pangkal batang kelapa sawit. Penelitian dilaksanakan di Kabupaten Luwu Utara, Luwu Timur, dan Makassar sejak bulan Januari sampai September 2017. Penelitian ini terdiri atas empat tahap, yaitu isolasi bakteri endofit, uji aktivitas kitinolitik, uji antagonis dan identifikasi secara biokimia. Hasil penelitian diperoleh 14 isolat bakteri dimana dua bakteri diantaranya memiliki aktivitas kitinolitik dengan indeks masing masing 2,35 dan 3,37. Kedua bakteri tersebut dapat menghambat G. boninense pada medium padat masing masing 24,9% dan 69,4% serta pada medium cair masing masing 47,5% dan 68,5% lima hari setelah inokulasi. Berdasarkan karakterisasi secara biokimia, bakteri tersebut memiliki kemiripan dengan Bacillus sp, dan Serratia sp. Hasil penelitian menunjukkan bahwa Serratia sp. berpotensi dalam mengendalikan penyakit busuk pangkal batang pada kelapa sawit.
 

 
Pertumbuhan dan Produktivitas Beberapa Varietas Ubi Kayu dengan Tingkat Pupuk yang Berbeda di Lahan Tegakan Jati Muda
Authors: Wahyuningsih Sri , Sutrisno Sutrisno
Published: November 2019

Penelitian dilaksanakan pada lahan jati umur 2 tahun  di Perum Perhutani KPH Blora, Desa Bogem, Kecamatan Japah. Percobaan menggunakan rancangan petak terbagi, diulang empat kali. Petak utama adalah lima varietas ubi kayu yaitu: Adira 4, Malang 4, Litbang UK 2, Cecek Ijo, dan UJ 5. Anak petak adalah tiga dosis pemupukan yaitu: a) 100 kg Urea + 125 kg SP36 + 75 KCl (input rendah), b) 125 kg Urea + 150 kg SP36 + 100 KCl, (input sedang), c) 200 kg Urea + 200 kg SP36 + 125 kg KCl + 5000 kg pupuk kandang (input tinggi). Hasil penelitian menunjukkan tidak terdapat pengaruh interaksi antara varietas dengan pemberian pupuk terhadap hasil ubi kayu. Hasil ubi kayu dengan  input rendah, sedang, dan tinggi berturut-turut adalah 25,38 t, 27,29 t, dan 25,81 t/ha. Rata-rata hasil ubi tertinggi diperoleh Varietas Malang 4 (32,01 t/ha), kemudian diikuti Adira 4, Cecek ijo, UJ 5, dan Litbang UK 2, masing-masing 28,22 t, 27,64 t, 23,43 t dan 21,50 t/ha. Varietas Malang 4 memberikan hasil tertinggi dengan perlakuan input sedang (33,00 t/ha).