bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Model Pembelajaran Problem Based Learning Terhadap Higher Order Thinking Skills (HOTS)
Authors: Okta Pia Nur Afni , Masnur Masnur , Elihami Elihami
Published: September 2022

Salah satu strategi yang dapat digunakan untuk mengembangkan HOTS   adalah dengan menerapkan model pembelajaran yang membuat peserta didik aktif. HOTS bisa dilatihkan kepada siswa melalui beberapa model pembelajaran diantaranya model pembelajaranProblem Based Learning(PBL). Tujuan penelitian ini adalah untuk mendapatkan informasi mengenai Pengaruh ModelPBL Terhadap HOTS Peserta didik  Subtema Benda dalam Kegiatan onomi Kelas V SD Negeri 48 Garutu Kabupaten Enrekang. Lokasi penelitian dilakukan di SDN 48 Garutu Kabupaten Enrekang. Jenis penelitian yang digunakan adalah penelitian kuantitatif. Peneliti menggunakan metode penelitian Pre-Experimental Designs. Pada penelitian ini, diberikan pre-test sebelum diberiperlakuan. Dengan demikian hasil perlakuan dapat diketahui lebih akurat,karena dapat membandingkan dengan keadaan sebelum diberi perlakuan. Populasi dalam penelitian ini adalah seluruh siswa kelas Kelas V SD Negeri 48 Garutu Kabupaten Enrekang yang berjumlah 17 siswa. Laki-laki 7 orang dan perempuan 10 orang. Berdasarkan pertimbangan peneliti Sampel penelitian ini adalah siswa-siswi kelas V yang terdiri dari 17 siswa. Instrumen penelitian yang ingin digunakan dalam penelitian ini adalah tes. Teknik analisis data menggunakan analisis data statistic deskriptif dan analisis data statistic inferensial. Berdasarkan hasil penelitian menunjukkan bahwa penerapan model pembelajaran problem based learning (PBL) mampu meningkatkan kemampuan high order thinking skills (HOTS) atau kemampuan siswa dalam berpikir tingkat tinggi. Total skor HOTS peserta didik pada sebelum diberikan perlakuan penerapan model pembelajaran problem based learning (PBL) sebesar 984,375 dengan rata-rata 57,90 kemudian total skor HOTS peserta didik meningkat menjadi 1465,625 dengan rata-rata 86,21 pada saat diberikan perlakuan penerapan model pembelajaran problem based learning (PBL). Gain skor antara pre test dan post test sebesar 481,25 dengan rata-rata gain skor sebesar 28,30. Hasil uji menunjukkan bahwa nilai signifikansi sebesar 0,000 < 0,05 (α) sehingga dapat disimpulkan bahwa terdapat Pengaruh Penggunaan model PBL Terhadap HOTS Peserta didik.
Penerapan Model Pembelajaran Blended Learning untuk Meningkatkan Hasil Belajar Peserta didik Kelas VI pada tema 3 Subtema 2 di SDN 40 Lewaja
Authors: Sri Wahyuni Puput Muhammadiyah , Masnur Masnur , Assidiq Ilham
Published: September 2022

Penelitian ini bertujuan untuk meningkatkan hasil belajar peserta didik kelas VI Tema 3 subtema 2 di SDN 40 Lewaja Tahun Ajaran 2021/2022 melalui Penerapan Model Pembelajaran Blended Learning.Penelitian ini merupakan penelitian tindakan kelas (PTK) yang dilakukan secara kolabolator dengan guru kelas. Subjek dari penelitian ini adalah semua peserta didik kelas VI SDN 40 Lewaja yang berjumlah 8 peserta didik. Teknik pengumpulan data dilakukan dengan menggunakan tes hasil belajar, observasi dan dokumentasi. Teknik analisis data yang digunakan adalah analisis data deskriptif kuantitatif dengan persentase berupa perhitungan tes hasil belajar dengan hasil observasi. Hasil penelitian yang dilakukan meningkatkan hasil belajar peserta didik ranah kognitif, afektif dan psikomotor setelah penerapan 2 siklus. Jadi dapat disimpulkan bahwa Penerapan Model Pembelajaran Blended Learning dapat meningkatkan hasil belajar ranah kognitif, afektif dan psikomotor peserta didik kelas VI Tema 3 Subtema 2 SDN 40 Lewaja Tahun Ajaran 2021/2022.
Persepsi Siswa Mengenai Pengaruh Kreativitas Guru Terhadap Minat Belajar Siswa Kelas IV SDN 196 Buntu Kasisi Desa Tallung Ura Kecamatan Curio
Authors: Afifa Nurul , Aminullah Aminullah , Rahmat Rahmat
Published: September 2022

Penelitian ini dilakukan dengan tujuan mengetahui persepsi siswa mengenai pengaruh kreativitas guru terhadap minat belajar siswa kelas IV SDN 196 Buntu Kasisi Desa Tallung Ura Kecamatan Curio. Populasi dalam penelitian ini diambil dari keseluruhan peserta didik kelas IV SDN 196 Buntu Kasisi, Desa Tallung Ura, Kecamatan Curio yang berjumlah 9 orang siswa. Teknik pengambilan sampel dalam penelitian ini menggunakan sampel jenuh dimana jumlah sampel yang digunakan dalam penelitian ini adalah seluruh populasi yang berjumlah 9 orang siswa kelas IV SDN 196 Buntu Kasisi, Desa Tallung Ura, Kecamatan Curio. Pendekatan penelitian yang digunakan dalam penelitian ini adalah kuantitatif deskriptif dengan jenis penelitian ex post facto yang bersifat analisis regresi sederhana yang berfungsi untuk mencari besarnya pengaruh variabel X terhadap variabel Y dengan variabel X dari penelitian ini adalah persepsi siswa mengenai pengaruh kreativitas guru dan variabel Y dari penelitian ini adalah minat belajar siswa. Hasil penelitian yang diperoleh berdasarkan hasil wawancara dan hasil kuesioner yang di uji menggunakan bantuan Program SPSS versi 25,0 for windows 64 bit yaitu adanya pengaruh yang signifikan persepsi siswa mengenai kreativitas guru terhadap minat belajar siswa kelas IV SDN 196 Buntu Kasisi Desa Tallung Ura Kecamatan Curio.
Problems of Teachers in Providing Assessments of Students' Attitudes in the Learning Process
Authors: Pasino Sukmawari , Elihami Elihami
Published: September 2022

This study aims to find out how teachers assess student attitudes, teacher difficulties in assessing student attitudes, and the efforts made by teachers in overcoming difficulties in assigning values ​​to students' attitudes in the learning process based on the 2013 curriculum in elementary school. Research subjects as six teachers were selected using the purposive sampling technique. The approach used in this research is a qualitative approach with a descriptive type of research. Data collection techniques use observation and interviews. The data were analyzed using inductive logic, namely from specific to general. The conclusions of this study indicate that the teacher provides an assessment of student attitudes in the learning process based on the 2013 curriculum in elementary school by observing or making direct observations of students' attitudes during the learning process. The difficulty of teachers in assessing student attitudes in the learning process based on the 2013 curriculum in elementary schools in the limited time, the large number of students in one class, and the difficulty in directing students to instill good attitudes following learning objectives. Efforts made by teachers in overcoming difficulties in assigning grades to students' attitudes in the learning process based on the 2013 curriculum in elementary schools are by discussing with parents of students, coordinating with other teachers, and asking other students to get detailed information.
Upaya Meningkatkan Hasil Belajar pada Materi Berbahasa Krama Inggil Menggunakan Metode Bermain Peran dengan Model Pembelajaran Cooperative Learning
Authors: Ningrum SM
Published: September 2022

Class action research in general aims to improve the quality of learning for students of grade IV Purwoprajan II State Elementary School. Specifically aimed at: (1) Describe the activities of learners; (2) Describe the management of learning by the teacher; (3) Knowing the learning outcomes of learners who refer to role-playing methods with cooperative learning models in grade IV of Purwoprajan II State Elementary School even semester of the 2019/ 2020 school year for Javanese mulok subjects on krama inggil language material. Study subjects grade IV SDN Purwoprajan II Jebres Surakarta. Research data is obtained by observation and documentation. Then analyzed with descriptive qualitative. Research is conducted in two cycles in which each cycle consists of stages of planning, implementation, observation, and reflection. The results of the study concluded that the use of role-playing methods with cooperative learning models can increase the increase in the average value of learners in learning the language material in Javanese language content.
Concept of 'Meaning of Words and Terms' in Elementary School learning: A review of literature
Authors: Elihami Elihami
Published: September 2022

Many words are associated with more than one meaning. Words are sometimes "ambiguous", applying to unrelated meanings, but most of the words that occur frequently are "polysemy" because they apply to several related meanings. In a pre-registration design that includes 2 tasks, we test the ability of adults and children aged 4.5 to 7 years to learn 4 new polysemy words or 4 new ambiguous words especially in Indonesian subjects in primary school learning in learning in elementary school. Both children and adults demonstrated the superiority of polysemic learning over ambiguity on each task after exposure, showing better learning of new words with multiple related meanings than new words with unrelated meanings in primary school learning. We concluded that participants were adept at learning polysemy words that varied across multiple dimensions. The current results are consistent with the idea that the ambiguous meanings of a word compete, but that polysemous meanings reinforce each other in primary school learning.
Pengimplementasian Nilai Pancasilla pada Siswa SD Guna Meningkatkan Sikap Patritisme Cinta tanah Air
Authors: Auliadi Auliadi , Dewi Dinie Anggraeni
Published: September 2022

Pendidikan pancasila sangatlah penting bagi seluruh bangsa Indonesia, khususnya generasi muda saat ini. Pendidikan Pancasila juga merupakan upaya untuk menanamkan bagaimana seseorang harus memiliki kecintaan terhadap negara Indonesia yang tinggi. Sebagai bangsa yang memiliki sejarah Panjang dalam mencapai negara Indonesia merdeka maka bangsa harus memiliki rasa cinta pada tanah air, patriotisme dan nasionalisme. Seiring perkembangan zaman dan juga teknologi rasa cinta pada tanah air semakin berkurang karena maraknya budaya asing yang mempengaruhi bangsa Indonesia. Metode yang digunakan dalam penelitian yaitu metode kepustakaan. Tujuan dari penelitian ini adalah untuk memahami bagaimana pengimplementasian Pendidikan Pancasila bagi anak Sekolah Dasar (SD) agar tumbuh rasa cinta terhadap tanah air dan juga sikap patriotisme. Jika pancasila sudah diterapkan dalam kehidupan sehari-hari maka jiwa patriotisme dan juga cinta tanah air akan muncul dengan sendirinya. Upaya penguatan dalam membentuk generasi muda yang cinta tanah air mungkin dapat dilakukan pada anak Sekolah Dasar yang masih murni dan juga agar mereka lebih mengenal dan mencintai negaranya.
Menumbuhkan Rasa Nasionalisme dan Patriotisme Pada Anak Sekolah Dasar Melalui Pembelajaran IPS
Authors: Amalia Gina , Auliadi Auliadi , Rustini Tin , Arifin Muh. Husen
Published: September 2022

Many Indonesian citizens, including elementary school children, have been carried out by external developments due to increasing technological growth. They forget that the true identity of an Indonesian citizen is to love his own country. Therefore, more is needed to improve nationalism in Indonesia, which starts as early as at Sd through ips study. The education materials given are about Indonesia's independence process. At the first meeting before class, children are taught to pray before and after learning to create a religious consciousness so that children realize that in the Indonesian state, there is a variety of religions and a growing love for the Indonesian state. Additionally, there are methods given during learning that are contextual teaching and learning (TCL) and higher order thinking skill (hots). Contextual teaching and learning (TCL) is a system that links learning materials to daily life, such as taking the possible values of Indonesia's independence from hard work, cooperation, and foremost nationalism and patriotism. Then, there is called higher order thinking skill (hots) which is the method of discussion students perform about taking a meaning from the Indonesian independence event. With such a method, it will add to the student's knowledge and love of the country. In addition, students become proficient at thinking critical of the learning materials. As a result of this writing was the invention of several methods and ways that a teacher can promote nationalism in elementary school students by studying ips related materials for Indonesia's independence process. Not only teachers but parents also contribute greatly to the efforts of increasing nationalistic values in their children
Menurunnya Nilai Pancasila Sila Ke 5 Sebagai Dampak Perkembangan Teknologi Pada Kaum Generasi Milenial
Authors: Adhari Febby Nur , Dewi Dinie Anggraeni
Published: September 2022

Abad ke 21 merupakan abad yang identic dengan teknologi, pada abad ini teknologi berkembang dengan sangat pesat. Dengan adanya gadget yang semakin canggih segala sesuatu bisa dilakukan didalam rumah, salah satunya adalah berbelanja. Dengan gadget kita bisa berbelanja di rumah saja secara mudah, praktis, dan cepat. tetapi ternyata hal ini juga berdampak buruk bagi masyarakat Indonesia karena menimbulkan perilaku konsumtif terutama pada generasi millennial. Perilaku konsumtif ini juga bertentangan dengan pancasila sila ke 5 yaitu tidak bersifat boros dan tidak bergaya bermegah-megahan. Artikel ini Penulisan karya ilmiah ini menggunakan metode kualitatif deskriptif atau study pustaka yang menelaah jurnal-jurnal yang telah diterbitkan secara nasional maupun internasional. Penulisan karya ilmiah ini juga bertujuan untuk mengetahui mengkaji mengenai menurunnya nilai pancasila sila ke 5 sebagai dampak  perkembangan teknologi terhadap perilaku konsumtif pada generasi milenial.
Penggunaan Makna Diksi dalam Novel “Senja Hujan dan Cerita yang telah Usai” oleh Boy Candra
Authors: Syahputra Edi , Syafira Syafira , Rizky Septiana
Published: September 2022

Diksi merupakan pemilihan kata yang tepat untuk menciptakan suatu kalimat yang sesuai dengan kondisi dan makna yang selaras kemudian tersampaikan dengan baik kepada pendengar hingga tidak menimbulkan kesalahpahaman dalam berbahasa. Dalam penelitian ini dijelaskan bahwasannya jenis diksi berdasarkan maknanya terbagi atas dua yaitu denotasi dan konotasi. Makna denotasi adalah makna sebenarnya yang apa adanya sesuai dengan indera manusia. Kata yang mengandung denotatif mudah dipahami karena tidak mengandung makna yang rancu walaupun masih bersifat umum. Sementara makna konotasi adalah makna yang tidak sebenarnya, makna yangh telah mengalami penambahan pada makna dasarnya, yakni hanya tambahan yang bersifatnya memberi nilai rasa, baik positif maupun negatif. Kemudian, rangkaian diksi banyak digunakan dalam penulisan karya-karya seperti novelSehingga, penelitian ini bertujuan untuk menganalisis isi novel yang terdapat kandungan diksi yang bermakna konotasi dan makna denotasi. Penelitian ini memiliki sumber data yaitu dari novel “ Senja Hujan & Cerita Yang Telah Usai” karya Boy Candra. Dalam penelitian ini, teknik pengumpulan data yang digunakan adalah dengan dokumentasi dan teknik catat. Sementara, Metode penelitian yang digunakan dalam penelitian ini adalah metode kualitatif deskriptif. Hasil penelitian tersebut yaitu bahwa secara keseluruhan variasi yang paling dominan terdapat pada makna konotasi, oleh karena itu novel tersebut mempunyai kelebihan tersendiri yakni menarik untuk di baca karena mempunyai nilai rasa yang dalam dan nilai estetik pada novel tersebut. Novel tersebut juga berhasil membuat pembaca seakan merasakan apa yang tertulis di novel. Untuk itu, pengarang juga berhasil telah membuat para pembaca me nikmati alur ceritanya sementara makna yang paling dominan adalah ameliorasi tersebut banyak digunakan karena sesuai dengan konteks cerita pada novel tersebut.
Filsafat Ilmu, Perkembangannya dan Pandangan Filsafat
Authors: Tarigan Mardinal , Hamidiyah Masita , Nasution Masriyanti , Tanjung Rahmi Rahmita
Published: September 2022

Historically, philosophy has always been the mother of science. In its development, science is increasingly independent and concrete. However, in the face of many life problems that science cannot answer, philosophy became the basis for answering the problem. Before the 17th century, science was synonymous with philosophy. Philosophy itself is a broad science, meaningz that it is closelyz relatedz to our daily lives. Therefore, the philosophyz of sciencez can be seen as an attemptz to bridgez thez gapz betweenz philosophyz andz science. The urgency of the philosophyzof sciencez can be seen from its role asz a keyz dialogue partner in the development of science. The philosophy of science is also a philosophicalz reflectionz of the naturez ofz science, and does notz recognizez the end of the achievement of goals. Understandingz thez philosophyz ofz sciencez meansz understandingz thez complexity ofzscience, so thatz its mostz basicz aspectsz are also understood from the perspectivezofzscience, the development of science, and thez interrelationshipszbetween brancheszofzscience, which cannot be separated from a philosophical paradigm. Thez researchzmethod thatz researchersz usez when writingz scientificz papersz isz az typez of literature research. Itz can bezconcludedzthat philosophy is a sciencez thatz studiesz thez naturez of allz things. Sciencezis an objective way of thinkingzabout the real world and giving it meaning.
Arah dan Orientasi Filsafat Ilmu di Indonesia
Authors: Tarigan Mardinal , Gustiana Dinda , Lestari Tiara Dwi , Fadhilah Qorri , Hidayat Yulia
Published: September 2022

Filsafat Ilmu is one of the specific Filsafats that has a strategic position in Indonesia's development of the ilmu paradigm. Filsafat's position in the evolving paradigm of knowledge will be examined in this research. Some of the things that were discussed in this study are listed below. In Indonesia, Filsafat Ilmu is a paradigm and a way of life. At addition, Filsafat Ilmu students in Indonesia's kuliah madrasah are encouraged to read and learn about the school's many books of poetry and prose. Filsafat Ilmu is a discipline of the Indonesian Filsafat that is gaining traction. The purpose of this study is to analyze and decipher the aims and progress of Filsafat Ilmu in Indonesia from the perspective of the paradigm of ilmu and the history of its transmission through Indonesian books and scholarly articles. It is used in the study of Filsafat Ilmu to use a method of research known as kualitatif, which involves analyzing the sources or data from books, journals, documents, and textbooks. Interpretation, heuristics, and philosophical reflection are all forms of analytic methods used. Research shows that Filsafat Ilmu is being developed and taught in line with the current paradigm for Filsafat Ilmu. It is this structure that was built to help grow Filsafat Ilmu, starting with the fundamental understanding of Filsafat's fundamentals all the way down to its core tenets. Orientasi Flsafat Ilmu, a discipline derived from the Filsafat that was developed in Indonesia from a variety of literature, still dominates on the orientation of Filsafat barat.
Filsafat Ilmu sebagai Landasan Pengembangan Ilmu Pendidikan
Authors: Tarigan Mardinal , Yasmin Feby Annisa , Rifai Akrizal , Yusriani Yusriani , Azmi Khairul , Azmi Khairul
Published: September 2022

The philosophy of science clarify the existence of science to the other science that requires knowledge as a medium of thinking and means of scientific communication. These are language, logic, mathematics, statistics, and other data analysis techniques. Specifications and independency science faced by the increasing number problems that can not be answered by science, therefore, philosophy appears as the answer. Philosophy gives an explanation or an answer onthat problems substantial and radical, while the science continues to develop it self- in its limit , while still radically criticized, process or the interaction basically is a field of philosophy of science. Philosophy of science therefore can be put as an attempt to bridge the gap between the philosophy and science, so that science does not despise the philosophy, and the philosophy does not see science as a superficial understanding of nature . Reality is “what is naturally “ or existence , while the appearance is that “artificially real“. Also how the relationship to both with subject /human. Epistemology is considered synonymous with the theory of knowledge. At the present time theory of knowledge can not be ignored. Epistemology of education science related to know how science education obtaining gain processing, what is the procedure to get the true scientific knowledge. Axiologiy related to what is the advantages of science education, what ethical relationship with science and its application science education in daily life . Key words : the philosophy of science, education, ontology, epistemology, axiology.
Sikap Masyarakat Jalan Sentosa Lama GG Perwira Kel. SEI Kerahulu Kecamatan Medan Perjuangan Medan Terhadap Pentingnya Pendidikan Islam
Authors: Daulai Afrahul Fadhila , Azmi Khairul , Nasution Anggi Rahmanida , Siregar Aisyah Rizqa , Yusriani Yusriani , Hasibuan Ardina Khoirunnisa
Published: September 2022

This study discusses the attitude of the community towards the importance of Islamic education on Jalan Sentosa Lama, the alley of the Medan Struggle District Officers. This study aims to determine the public’s attitude towards the importance of Islamic education on Jalan Sentosa Lama alley of the district officer. Battlefield. To identify the contribution of society in the implementation of Islamic education for the younger generation. The type of research conducted is descriptive qualitative. The source of the research data is purely the result of the field by interviewing a person from the community. The results of the study showed that there was still a lack of knowledge about Islamic values ​​in the community, it was proven that the number of worshipers was small even though the mosque in the neighborhood was very close. The opportunity for implementing Islamic religious education for the younger generation is very small because at this time they can argue and also they spend more time with useless things, one of which is by playing gadgets
Pengaruh Pengunaan Alat Kontrasepsi dengan Kejadian Kematian Neonatal Dini
Authors: Fatiah Mona Safitri
Published: September 2022

Introduction: Early Neonatal Death gave of 2/3 infact death. The purpose this study aim to the effect of family planning with early neonatal death. Methode: This study is a quantitative study with the design of case kontrol research at primary health care in Sarmi on June 1st - November 31st, 2020 with case samples are mothers who experienced early neonatal death of 34 people and kontrol samples are mothers who did not experience early neonatal events of 166 people with a ratio of 1: 5. This study uses medical record data in 2017-2019 Puskesmas Sarmi with logistic regression analysis of risk faktor models processed using STATA 14. Results: The results of this study indicate that there is an effect of using contraceptives on early neonatal mortality after being controlled by confounding variables such as gestational age, gestational age, LILA, Hb levels, and ethnicity (p value 0.0001 with an OR value of 11.4 (95%CI= 4.5 – 29.5). Optimization of care mentoring roles in efforts to increase PUS and WUS participation in the Birth Kontrol Program to prevent and reduce early neonatal deaths.
 
 
ABSTRAK
Pendahuluan: Kematian neonatal dini menyumbangkan sekitar 2/3 kematian anak. Tujuan: untuk melihat pengaruh penggunaan alat kontrasepsi dengan kematian neonatal dini. Metode: Penelitian ini merupakan penelitian kuantitatif dengan desain penelitian case kontrol yang dilakukan di Puskesmas Sarmi pada tanggal 1 Juni – 31 November 2020 dengan sampel kasus adalah ibu yang mengalami kejadian neonatal dini sejumlah 34 orang dan sampel kontrol adalah ibu yang tidak mengalami kejadian neonatal dini sejumlah 166 orang dengan perbandingan 1: 5. Penelitian ini menggunakan data rekam medik tahun 2017-2019 Puskesmas Sarmi dengan analisis logistic regression model faktor risiko yang diolah menggunakan STATA 14. Hasil: Hasil penelitian ini menunjukkan adanya pengaruh penggunaan alat kontrasepsi terhadap kematian neonatal dini setelah di kontrol oleh variabel konfoding berupa usia kehamilan, jarak kehamilan, LILA, Kadar Hb, dan suku (p value 0,0001 dengan nilai OR sebesar 11,4 (95% CI= 4,5 – 29,5). Optimalisasi peran pendampingan kader dalam upaya meningkatkan partisipasi PUS dan WUS pada Program KB untuk mencegah dan mengurangi kematian neonatal dini.
Analisis Faktor Risiko Kematian Pasien Covid-19 Di Rumah Sakit Umum Daerah Undata Palu
Authors: Kunoli Firdaus Hi. Jahja , Rahayu Sri
Published: September 2022

World Health Organization (WHO) menyatakan pandemik global terhadap virus corona karena virus ini sudah menyebar secara masif dan sangat  luas ke seluruh dunia. Indonesia kasus pertama Covid-19 terkonfirmasi pada awal Maret tahun 2020 dan pada bulan April tahun 2020 penyebarannya telah meluas di 34 provinsi di Indonesia dengan jumlah kasus Covid-19  di Indonesia sudah mencapai angka 406.945 kasus, dengan jumlah kesembuhan mencapai 334.295 kasus dan angka pasien yang meninggal sebanyak 13.782 kasus. Penelitian ini bertujuan untuk diketahuinya faktor risiko kematian pasien COVID-19 di RSUD Undata Palu. Penelitian ini menggunakan jenis penelitian survey analitik dengan metode Cross Sectional Study. Dengan jumlah sampel sebanyak 62 sampel yang terdiri dari 31 kasus dan 31 kontrol dengan menggunakan uji Statistik yaitu Odds Ratio. Hasil uji statistik dengan  uji Odds Ratio menunjukan bahwa umur    merupakan faktor risiko terhadap kematian pasien COVID-19 dengan nilai OR 5.975>1, jenis kelamin  merupakan faktor risiko terhadap kematian pasien COVID-19 dengan nilai OR 1.304>1 dan komorbid  merupakan faktor risiko terhadap kematian pasien COVID-19 dengan nilai OR 11.979 > 1. Saran dalam penelitian ini adalah bagi agar lebih meningkatkan upaya promotif dan preventif dengan cara memberikan penyuluhan tentang faktor risiko  sehingga dapat terhindar dari kematian akibat COVID-19 dan lebih meningktkan pola hidup sehat dan mencegah faktor pencetus dan merubah gaya hidup yang dapat menyebabkan terpapar virus COVID-19
Analysis of Birth Weight and Birth Length with Stunting Incident in Children Aged 0-59 Months in Cinangka Depok
Authors: Hidayati Ahid Nur , Aprianto Bagus , Herbawani Chahya Kharin
Published: September 2022

In Indonesia, the frequency of child stunting has remained high over the last decade, with an estimated 37 percent of children stunted at the national level. The prevalence of stunting in Depok accounted for 3.5% of the incidence of stunting, which means that as many as 3,675 of 105,127 children under five experienced stunting in Depok. Data from the Cinangka Primary Health Center, Depok, in 2022 showed 158 children experiencing stunting. This study aims to see whether there is a relationship between birth weight and body length with the frequency of stunting in children aged 0-59 months. With a cross-sectional study approach, primary data were obtained directly from 56 samples of children aged 0-59 months who were stunted by anthropometric examination and interviews with questionnaires. The analysis used Chi-Square statistical test. The result showed that the prevalence of stunting, low birth weight, and low birth length were 80.4%, 25%, and 48.2%. The study found no relationship between birth weight and birth length with the incidence of stunting in children aged 0 to 59 months at the Cinangka Primary Health Center, Depok. Stunting was caused by a complex set of circumstances that included not just the child's birth weight and length but also their nutritional intake, disease exposure, and therapy. The study's outcomes show that comprehensive treatments are needed to improve the stunting incidence in Cinangka Primary Health Center, Depok. Multilevel approaches should be used in interventions to address numerous elements at all levels, from the community to the individual
Pengaruh Senam Diabetes Mellitus terhadap Penurunan Kadar Gula Darah pada Penderita Diabetes Mellitus Tipe 2
Authors: Nelyta Oktavianisya  , Aliftitah Sugesti
Published: September 2022

Macam-macam tatalaksana penyakit diabetes antara lain edukasi, pengaturan makanan, latihan fisik, dan intervensi farmakologis. Latihan fisik, salah satunya senam diabetes merupakan  salah satu upaya pertama  dalam pencegahan,  kontrol, dan mengatasi diabetes. Tujuan penelitian untuk mengetahui pengaruh senam diabetes terhadap penurunan KGD pada penderita DMT2. Desain penelitian adalah pra-eksperimental, one group pra-post test design. Sampel dalam penelitian ini ada 35 responden dengan tekhnik pengambilan sample yang digunakan yaitu teknik simple random sampling. Variabel bebas yaitu senam diabetes dan variable terikat yaitu KGD. Pengukuran KGD menggunakan Glucotest. Data dilakukan analisis dengan menggunakan uji Paired Samples T Tes. Hasil penelitian didapatkan rata-rata KGD setelah dilakukan senam terdapat penurunan sebesar 19,49 mg/dL. Hasil uji analisis data pretest-posttest kadar gula darah menggunakan uji Paired Samples T Test didapatkan nilai ρValue=0,000 dengan α=0,05. Karena ρValue<α maka ada pengaruh senam DM terhadap Penurunan KGDpada Penderita DMT2. Dengan melakukan senam DM pasien DMT2 bisa mengontrol kadar gula darahnya
Performance of Invention Toddler Pneumonia Cases in Public Health Centers Municipality Jambi
Authors: Sari Rumita Ena , Wardiah Rizalia , Tari Putri Inrian
Published: September 2022

The prevalence of toddler pneumonia in Jambi was fluktuative since 2019, and never achived of minimal standart services. This study aims to determine performance of finding pneumonia under five by health workers at the Jambi City Health Center in 2021. This type of research was a quantitative study with a Cross Sectional design. The sampling technique used a total sampling of 60 health workers. Data collected by using a questionnaire. The results showed that there was a significant relationship between motivation,, supervision,, support from the head of the health center, training, and support from colleagues, with performance of finding pneumonia. It is hoped that the health center will carry out outreach efforts to the community regarding the prevention of pneumonia which is integrated with the STOP Pneumonia program. It is also hoped that the Jambi City Health Office will routinely hold training on pneumonia under five.
Hubungan Lingkar Lengan Atas (LiLA), Hemoglobin (Hb), dan Asupan Fe Terhadap Berat Badan Lahir Bayi
Authors: Nuryani  , Ayu Mustika Handayani
Published: September 2022

Berat badan lahir merupakan salah satu indikator kesehatan bayi baru lahir dan sebesar 16% dari semua bayi lahir dengan BBLR. Faktor penyebab terhadap kejadian bayi baru lahir dengan berat lahir rendah (BBLR) dilihat dari lingkar lengan atas (LiLA), hemoglobin (Hb), dan zat besi di dalam tubuh ibu hamil. Tujuan penelitian untuk mengetahui hubungan LiLA, Hb, dan zat besi dengan berat badan lahir bayi. Metode penelitian menggunakan survey analitik dengan pendekatan retrospektif. Populasi penelitian adalah ibu yang melahirkan di Wilayah Kerja Puskesmas Tangkit pada bulan Januari-Desember 2020. Teknik pengambilan sampel menggunakan total sampling. Sampel penelitian ini sebanyak 212 responden. Uji analisa data menggunakan chi square. Hasil penelitian didapat ada hubungan LiLA dengan berat badan lahir bayi dengan p-value 0,022, OR sebesar 0,231(0,061-0,874). Tidak ada hubungan kadar hemoglobin dengan berat badan lahir bayi dengan p-value 0,703, nilai OR sebesar 1,382 (0,497-3,839). Ada hubungan asupan zat besi (Fe) dengan berat badan lahir bayi dengan p-value 0,759, dengan nilai OR sebesar 0,770 (0,297-2,001). Kesimpulan penelitian ini adalah terdapat hubungan LiLA dengan berat badan lahir bayi. Pada variabel kadar hemoglobin dan asupan zat besi (Fe) tidak menunjukkan hubungan yang signifikan dengan berat badan lahir bayi di Wilayah Kerja Puskesmas Tangkit.
Evaluasi Klinis dan Efek Samping Terapi Obat Antivirus Pada Pasien Covid-19 Di RSPAD Gatot Soebroto
Authors: Mangiwa Jeanette , Sumarny Ros , Laksmitawati Dian Ratih , Septini Renni
Published: September 2022

Tujuan penelitian ini adalah untuk menganalisa hubungan jenis obat antivirus Covid-19 dengan outcome klinis dan lama rawat berdasarkan derajat keparahan Covid-19 di ruang rawat inap Paviliun Soehardo Kertohusodo RSPAD Gatot Soebroto Jakarta. Penelitian ini merupakan penelitian observasional analitik dan pengambilan data secara retrospektif melalui rekam medis periode bulan September - November tahun 2020. Sampel adalah pasien Covid-19 derajat sedang dan berat. Data demografi dan klinis pasien serta profil pengobatan dianalisis secara deskriptif berdasarkan derajat keparahan Covid-19. Analisis data yaitu uji Spearman’s rho. Hasil menunjukkan terdapat 79 pasien Covid-19 yang memenuhi kriteria inklusi dengan derajat sedang 62,03% dan derajat berat 37,97%. Penggunaan antivirus pada derajat sedang yaitu oseltamivir sebanyak 28 pasien (57,14%), favipiravir 13 pasien (26,53%) sedangkan penggunaan antivirus pada derajat berat adalah oseltamivir & favipiravir. Hubungan lama status positif RT-PCR dan lama rawat terhadap derajat keparahan Covid-19 diperoleh p <0,05. Hubungan profil penggunaan obat antivirus dengan derajat keparahan Covid-19 diperoleh p=0,00. Hubungan jenis regimen obat antivirus dengan nilai skala rasio parameter klinik d-dimer pre p=0,01 dan post p=0,03 dan parameter klinik SGPT (pre) p=0,04 da (post) p=0,00 pada derajat berat. Kesimpulan yaitu terdapat hubungan yang signifikan profil penggunaan regimen obat antivirus dengan derajat keparahan Covid-19 dan terdapat hubungan yang signifikan pada penggunaan obat penunjang yaitu antikoagulan, antihistamin, obat gangguan saluran cerna dan obat hepaprotektor dengan derajat keparahan Covid-19
Pengaruh Konsumsi Buah Pisang Ambon (Musa Paradisiaca var Sapientum Linn) terhadap Peningkatan Kadar Hb pada Ibu Hamil dengan Anemia di Wilayah Kerja Puskesmas Kayamanya
Authors: Siregar Nilda Yulita , Noya Fransisca , Candriasih Putu
Published: September 2022

Pencegahan anemia dapat dilakukan pengobatan relatif secara mudah dan murah. Salah satu alternatifnya adalah mengonsumsi buah pisang ambon untuk memenuhi asupan zat besi bagi pasien anemia. Tujuan penelitian ini adalah untuk menganalisis pengaruh konsumsi buah pisang ambon (Musa Paradisiaca var Sapientum Linn) terhadap peningkatan kadar Hb pada ibu hamil dengan anemia di Wilayah Kerja Puskesmas Kayamanya. Rancangan penelitian yang digunakan adalah studi Quasi Eksperimental, dengan rancangan  pretest-posttest control group design.  Pengambilan sampel pada penelitian ini adalah purposive sampling dengan jumlah sebesar 44 orang. Data diolah dan dianalisis dengan menggunakan distribusi frekuensi dengan ukuran persentase dan uji Wilcoxon. Hasil penelitian ini menunjukkan rerata kadar Hb mengalami peningkatan pada kelompok kasus dari 9,09 mg/dl menjadi 10,13 mg/dl dan pada kelompok kontrol dari 8,95 mg/dl menjadi 9,42. Hasil uji statistik menunjukkan terdapat perbedaan bermakna sebelum dan setelah intervensi dan kelompok kontrol dengan nilai 0,000 (p<0,05). Kesimpulan yaitu terdapat pengaruh konsumsi buah pisang ambon (Musa Paradisiaca var Sapientum Linn) terhadap peningkatan kadar Hb pada ibu hamil dengan anemia di Wilayah Kerja Puskesmas Kayamanya
First in-human quantitative plaque characterization with ultra-high resolution coronary photon-counting CT angiography
Authors: Mergen Victor , Eberhard Matthias , Manka Robert , Euler André , Alkadhi Hatem
Published: September 2022

Purpose

To assess the effect of ultra-high-resolution coronary CT angiography (CCTA) with photon-counting detector (PCD) CT on quantitative coronary plaque characterization.

Materials and methods

In this IRB-approved study, 22 plaques of 20 patients (7 women; mean age 77 ± 8 years, mean body mass index 26.1 ± 3.6 kg/m2) undergoing electrocardiography (ECG)-gated ultra-high-resolution CCTA with PCD-CT were included. Images were reconstructed with a smooth (Bv40) and a sharp (Bv64) vascular kernel, with quantum iterative reconstruction (strength level 4), and using a slice thickness of 0.6, 0.4, and 0.2 mm, respectively (field-of-view 200 mm × 200 mm, matrix size 512 × 512 pixels). Reconstructions with the Bv40 kernel and slice thickness of 0.6 mm served as the reference standard. After identification of a plaque in coronary arteries with a vessel diameter ≥2 mm, plaque composition was determined using a dedicated, semi-automated plaque quantification software. Total plaque, calcified, fibrotic, and lipid-rich plaque components were quantified in all datasets.

Results

Median plaque volume was highest (23.5 mm3, interquartiles 17.9–34.3 mm3) for reconstructions with the reference standard and lowest for ultra-high-resolution reconstructions with a slice thickness of 0.2 mm and the Bv64 kernel (18.1 mm3, interquartiles 14.1–25.8 mm3, p < 0.001). Reconstructions with the reference standard showed largest calcified (85.1%, interquartiles 76.4–91.1%) and smallest lipid-rich plaque components (0.5%, interquartiles 0.0–1.5%). Smallest calcified plaque components (75.2%, interquartiles 69.9–80.8%) and largest lipid-rich components (6.7%, interquartiles 5.1–8.4%) were found for ultra-high-resolution reconstructions with a slice thickness of 0.2 mm and the Bv64 kernel. At an identical slice thickness, volume of calcified components was always lower, and volume of lipid-rich components was always higher for reconstructions with the Bv64 kernel compared with reconstructions with the Bv40 kernel (all, p < 0.001).

Conclusion

This patient study indicates significant differences of ultra-high-resolution scanning with PCD-CT on quantitative coronary plaque characterization. Reduced blooming artifacts may allow improved visualization of fibrotic and lipid-rich plaque components with the ultra-high-resolution mode of PCD-CT.
Immunoporosis: Role of immune system in the pathophysiology of different types of osteoporosis
Authors: Zhang Weidong , Gao Ruihan , Rong Xing , Zhu Siqi , Cui Yajun , Liu Hongrui , Li Minqi
Published: September 2022

Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone microarchitecture, with an increased risk of fractures. Classical theories hold that osteoporosis is essentially a bone remodeling disorder caused by estrogen deficiency/aging (primary osteoporosis) or secondary to diseases/drugs (secondary osteoporosis). However, with the in-depth understanding of the intricate nexus between both bone and the immune system in recent decades, the novel field of “Immunoporosis” was proposed by Srivastava et al. (2018, 2022), which delineated and characterized the growing importance of immune cells in osteoporosis. This review aimed to summarize the response of the immune system (immune cells and inflammatory factors) in different types of osteoporosis. In postmenopausal osteoporosis, estrogen deficiency-mediated alteration of immune cells stimulates the activation of osteoclasts in varying degrees. In senile osteoporosis, aging contributes to continuous activation of the immune system at a low level which breaks immune balance, ultimately resulting in bone loss. Further in diabetic osteoporosis, insulin deficiency or resistance-induced hyperglycemia could lead to abnormal regulation of the immune cells, with excessive production of proinflammatory factors, resulting in osteoporosis. Thus, we reviewed the pathophysiology of osteoporosis from a novel insight-immunoporosis, which is expected to provide a specific therapeutic target for different types of osteoporosis.
Modified Qing’ e Pills exerts anti-osteoporosis effects and prevents bone loss by enhancing type H blood vessel formation
Authors: Lu Junjie , Hu Desheng , Ma Chen , Xu Xiaojuan , Shen Lin , Rong Jianhui , Zhao Jia , Shuai Bo
Published: September 2022

Objective

To explore whether the modified Qing’ e Pills (MQEP) exerts anti-osteoporotic effects and prevents bone loss by enhancing angiogenesis.

Methods

Network pharmacology was used to assess whether MQEP has a pro-angiogenic capacity and to predict its potential targets. Human umbilical vein endothelial cells were treated with glucocorticoids and MQEP to assess cell viability. The expression of angiotensin II type 1 receptor, angiotensin II type 2 receptor, and angiotensin converting enzyme, which are associated with the activation of the renin-angiotensin-aldosterone system, and the expression of vascular endothelial growth factor and hypoxia-inducible factor 1 alpha, which are associated with the formation of type H blood vessels, were examined by western blot and RT-qPCR. Thereafter, the glucocorticoid-induced osteoporosis model was established and intervened with MQEP. Femur scanning was performed with micro-computed tomography; trabecular spacing, trabecular thickness, and trabecular number were observed and calculated; the expression of nuclear factor-kappa B ligand and osteoprotegerin was detected by ELISA, and the ratio was calculated to evaluate the degree of bone resorption. Finally, type H blood vessels that were highly coupled to osteogenic cells were identified by immunohistochemistry staining and flow cytometry.

Results

This is the first study to reveal and confirm that MQEP could prevent bone loss in glucocorticoid-induced osteoporosis by promoting the expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor, which are highly associated with type H blood vessel formation. In vitro experiments confirmed that MQEP could effectively promote the proliferation of vascular endothelial cells and alleviate glucocorticoids-induced activation of the renin-angiotensin-aldosterone system, thereby reducing vascular injury.

Conclusion

MQEP exerts anti-osteoporosis effects and prevents bone loss by alleviating vascular injury caused by renin-angiotensin-aldosterone system activation and promoting type H blood vessel formation.
Towards a theoretical framework for the innovation in sustainability reporting: An integrated reporting perspective
Authors: Sun Yanqi , Davey Howard , Arunachalam Murugesh , Cao Yuanyuan
Published: September 2022

Integrated Reporting (IR), as a novel sustainability-oriented organizational reporting approach, is expected to produce better corporate reporting for stakeholders and promote greater transparency and accountability in the capital market. This paper offers a theoretical framework that integrates five mainstream IR theories: stakeholder theory, agency theory, signalling theory, legitimacy theory, and institutional theory. Based on the theoretical framework, there are three drivers for companies to improve their IR disclosure practices: to mitigate information asymmetry between the organisation and all stakeholders; to signal superior quality, legitimacy, and conformity to all stakeholders; and to discharge accountability to all stakeholders. Direct and indirect costs are the main factors that lead to poor IR disclosure practices. This study is the first attempt to construct an integrated theoretical framework for IR. The constructed framework can be adopted as a theoretical foundation for future empirical studies with regard to IR.
Does digital finance affect the quality of economic growth? Analysis based on Chinese city data
Authors: Liu Tinghua , Hu Mengyuan , Elahi Ehsan , Liu Xiao
Published: September 2022

With the support of national policies and continuous emergence and innovation of emerging technologies, digital finance has developed rapidly in China. Can digital finance become a new driving force to promote quality development of economic growth? This study empirically examined the effect mechanisms of digital finance on the quality of economic growth. The study used the entropy weight and technique for order preference by similarity to an ideal solution method to construct a comprehensive index system of economic growth quality. From 2011 to 2019, the panel data of 272 cities in China were collected. The study found that digital finance can promote the quality of China’s economic growth in the long run; when digital finance development increases by one unit, the quality of economic growth will increase by 0.013%, and the effect is more significant in less developed regions. The digital finance coverage, depth of use, and degree of digitalization had a significant impact on the quality of economic growth. The mechanisms showed that digital finance can promote the quality of economic growth by promoting and upgrading the industrial structure. In addition, we used the threshold model to test the non-linear relationship between digital finance and the quality of economic growth. Furthermore, the results showed that when digital finance was at a low level, it had a negative effect on the quality of economic growth. As digital finance developed further, it had a significant effect on the quality of economic growth, and this effect gradually slowed down. Moreover, we found that digital finance played a more significant role in promoting the quality of economic growth in central and western regions and areas where traditional finance was underdeveloped. Based on this study, developing countries should strengthen the construction of digital infrastructure and give full play to the role of digital finance in improving the quality of economic growth, so as to promote sustainable and healthy economic development.
Identification of signaling pathways associated with achaete-scute homolog 1 in glioblastomas through ChIP-seq data bioinformatics
Authors: Zhang Na , Zhang Jie , Liu Zhihong , Li Tushuai
Published: September 2022

Background: Achaete-scute homolog 1 transcription factors were important in the differentiation of neuronal-like glioblastoma (GBM) cancer stem cells (CSCs). To gain a better understanding of the role of ASCL1 in GBM, chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) data can be analyzed to construct their gene transcription regulation network.

Methods: GSE87618 was downloaded from the Gene Expression Omnibus, which is a famous database, in the field of biology. The filtered clean reads were mapped to the human genome utilizing the software of bowtie2. Then, differential peak analysis was performed by diffbind. Finally, the annotated gene functions and signaling pathways were investigated by Gene ontology function and kyoto encyclopedia of genes genomes (KEGG) pathway enrichment analysis. Moreover, the protein–protein interaction network (PPI) analysis of genes obtained from ASCL1 was carried out to explore the hub genes influenced by ASCL1.

Results: A total of 516 differential peaks were selected. GO analysis of functions revealed that promoter, untranslated region (UTR), exon, intron, and intergenic genes were mainly enriched in biological pathways such as keratinization, regulation of cAMP metabolic process, blood coagulation, fibrin clot formation, midgut development, and synapse assembly. Genes were mainly enriched in KEGG pathways including pentose phosphate pathway, glycosphingolipid biosynthesis—globo and isoglobo series, ECM–receptor interaction, and adherens junction. In total, 244 nodes and 475 interaction pairs were included in the PPI network with the hub genes including EGFR, CTNNB1, and SPTAN1.

Conclusion: EGFR, SPTAN1, and CTNN1B might be the potential down-stream genes of ASCL1 in GBM development, and CTNN1B might make contributions to GBM progression on regulating the cAMP pathway.