bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychological Empowerment, Job Satisfaction and Organizational Commitment Among Lecturers in Higher Education: Comparison of Six CEE Countries
Authors: Jordan Gašper , Miglič Gozdana , Todorović Ivan , Marič Miha
Published: March 2017

Background and Purpose: Organizations should implement new findings from the field of human resource management. If an organization wants to have successful and effective employees, they should be satisfied with all aspects of work and at the same time they should be feel commitment towards an organization. To have a full insight in employees, organizations have to take care of psychological side of employees, which manifests in psychological empowerment.

Design/Methodology/Approach: The survey was conducted among 409 university lecturers in Austria, Croatia, Czech Republic, Germany, Serbia, and Slovenia. The investigated constructs of psychological empowerment, job satisfaction and organisational commitment were compared. Spreitzer’s PEQ was used for the assessment of the psychological empowerment, Spector’s JSS for job satisfaction, and Allen’s and Meyer’s OCQ for the assessment of organisational commitment.

Results: The research showed that the highest level of psychological empowerment can be found among university lecturers from Serbia and the lowest from Germany. Job satisfaction level is the highest in Austria and the lowest in Slovenia. Affective organisational commitment is the highest in Slovenia and the lowest in Germany. Continuance organisational commitment scored the highest in Croatia and the lowest in Czech Republic. Additionally, the outcomes show the highest level of normative organisational commitment in Czech Republic and the lowest in Austria. Only affective organisational commitment was not found as statistically significant.

Conclusion: Knowledge of psychological empowerment, job satisfaction and organizational commitment can be helpful for leaders, because with this knowledge they can manage, develop and motivate employees properly.
Eco-management and audit scheme (EMAS) as an important element of the sustainable development policy on the example of public sector organizations
Authors: Myszczyszyn Janusz
Published: March 2017

The necessity to protect natural resources in accordance with the idea of sustainable development is an indisputable issue. Not only the industrial sector organizations, but those of the public sector as well must join this process. The Eco-Management and Audit Scheme can play an important role in this respect. 3.7 thousand organizations have already registered in the EU EMAS register, including, unfortunately, only 71 from Poland, of which almost 40% from the public sector. The author tries to set out the benefits, resulting for the public sector organizations from the implementation of the scheme, but also the barriers and weaknesses of the system, which makes it not very popular in Poland. The results of the author’s own research carried out in 2016 among representatives of EMAS system, inter alia, of public sector organizations in Poland were used for this purpose.
The significance of the European beaver (Castor fibre) activity for the process of renaturalization of river valleys in the era of increasing
Authors: Kusztal Piotr , Żeber-Dzikowska Ilona , Chmielewski Jarosław , Wójtowicz Bożena , Wszelaczyńska Elżbieta , Gworek Barbara
Published: March 2017

Changes in the environment that are caused by the activity of beavers bring numerous advantages. They affect the increase in biodiversity, contribute to improving the condition of cleanliness of watercourses, improve local water relations and restore the natural landscape of river valleys.

Rapid increase in the European beaver population in Poland in 21st century determines and accelerates the process of renaturalization of the areas that have undergone partial degradation as a result of anthropopressure. A singular example is the river valleys populated by beavers that have been adapted to people’s needs in the last centuries, which has inevitably exerted an undesirable effect.
Decontamination of a Diving Suit
Authors: Dąbrowiecki Zbigniew , Dąbrowiecka Małgorzata , Olszański Romuald , Siermontowski Piotr
Published: March 2017

When working in chemical or biological environments, contamination is an extremely dangerous issue for the rescue services of the fire department, police and the army.

Modern protective overalls worn by fire fighters or dry “Viking” diving suits made from neoprene or nylon covered with polyurethane, have been proven to ensure sufficient protection. However, once the contaminated area is left, there is a need to perform decontamination of the external and internal surfaces of the protective overalls; in order to ensure the clothing continues to offer a high level of comfort and to retain the durability of said protective clothing, it is of course also necessary to perform a drying procedure.

Moreover, there is a risk of a transfer of pathogenic micro-organisms between persons utilising the same protective clothes, particularly in the case of expensive specialist suits. Micro-organisms which may potentially spread through clothing include intestinal bacteria, such as: Salmonella, Shigella, Campylobacter, E. coli (including E. coli O157), C. difficile, viruses inducing infections of the upper respiratory tract and alimentary tract (noraviruses, rotaviruses, adeno and astroviruses). The risk of infection also involves the presence of the flu viruses, herpesviruses and pathogens transferred through skin, such as S. aureus (including MRSA), yeast-like fungi (Candida albicans), fungal strains inducing Tinea pedis and Tinea corporis [1]. Pathogenic micro-organisms can easily transfer from fabric surface onto the body of a person wearing protective clothing.

From the numerous available techniques of decontamination of surfaces, equipment and protective clothing we propose to use for this purpose gaseous hydrogen peroxide (H2O2), a very effective biocidal agent. In field conditions, typical for the activities of rescue crews of the fire department, police and army we assume utilisation of a portable decontamination chamber enabling performance of a complete decontamination process.

The process lasting approximately 3 hours encompasses 3 phases:

• Drying phase;

• Decontamination with gaseous hydrogen peroxide;

• Catalytic combustion phase of hydrogen peroxide residues to a level safe for the environment.

The integrated humidity and H2O2 level sensors ensure automatic control of the entire process and the unique distribution system of gaseous H2O2 secures full accessibility of the biocidal agent to the external surface of protective clothing as well as its interior. Moreover, the container allows for the conduction of the complete decontamination of the rescue equipment, night vision devices, binoculars, field telephones, radio stations, etc. Upon decontamination cycle completion, we obtain a completely dried suit which can be safely used by another crew member.
Gesundheitskompetenz von gesetzlich Krankenversicherten
Authors: Zok Klaus
Published: March 2017

In einer bundesweiten Repräsentativ-Umfrage zur Messung von Gesundheitskompetenz schneiden die Versicherten der Gesetzlichen Krankenversicherung gegenüber einer als Referenz herangezogenen europäischen Studie unterdurchschnittlich ab. Aus Sicht der Krankenkassen stellt das Handlungsfeld der Gesundheitskompetenz einen wichtigen Ansatz dar, um eine angemessene Nutzung des Gesundheitswesens zu erzielen und um eine Steigerung der Lebensqualität der Menschen zu erreichen. Angesichts der Ergebnisse sind dazu gesamtgesellschaftliche Anstrengungen erforderlich.
Gemeinschaftliche Selbsthilfe und Gesundheitskompetenz
Authors: Kofahl Christopher
Published: March 2017

Das Wissen über Krankheit und Behinderung sowie deren Bewältigung sind zentrale Ziele von Selbsthilfemitgliedern. Die Befähigung zur Krankheitsbewältigung durch gemeinschaftliche Selbsthilfe wurde häufig unter der Überschrift „Empowerment“ thematisiert. Das sich erst in jüngerer Zeit etablierende multidimensionale Konstrukt der Gesundheitskompetenz weist eine erhebliche Überlappung mit dem Empowerment-Konzept auf und verkörpert somit in treffender Form die wesentlichen Ziele der gemeinschaftlichen Selbsthilfe.
Gesundheitliche Kompetenz erhöhen,
Patientensouveränität stärken
Authors: Hölling Günter
Published: March 2017

Eine Verbesserung der gesundheitlichen Kompetenz bzw. Gesundheitskompetenz und
eine Stärkung der Patientensouveränität sind 2003 als
nationales Gesundheitsziel in Deutschland formuliert worden. Im Rahmen des
Kooperationsprojekts „gesundheitsziele.de“ folgte 2010 eine
Aktualisierung des Ziels. Mittlerweile wurde dieses Gesundheitsziel im
Präventionsgesetz von 2015 aufgenommen.
Forderung der Gesundheitskompetenz – Erfahrungen im Rahmen der Patientenuniversitat
Authors: Seidel Gabriele
Published: March 2017

Die Forderung der Gesundheitskompetenz in den Bereichen Wissen, Interaktion und kritischer Reflektion ist Ziel einer regionalen Bildungsinitiative. Eine besondere Lernarchitektur verbindet wissenschaftlich fundierte Wissensvermittlung mit interaktiven Elementen. Aus Sicht der Teilnehmenden sind auf allen Ebenen der Gesundheitskompetenz Wirkungen spurbar. Das Konzept sollte von anderen Institutionen ebenfalls angeboten werden und auch in einer zugehenden Bildung in Betrieben umgesetzt werden.
Patientenschulungen bei chronisch kranken Kindern, Jugendlichen und Eltern
Authors: Szczepanski Rüdiger
Published: March 2017

Chronische Erkrankungen bei Kindern und Jugendlichen haben für die Familien große, auch psycho-soziale Herausforderungen zur Folge. Patientenschulungen fördern die notwendigen Kompetenzen, um diese Herausforderungen möglichst eigenständig zu meistern. Schulungen sind pädagogische/psychologische Interventionen mit handlungsrelevanten Inhalten und werden gemäß § 43 SGB V sowie den Rahmenempfehlungen der GKVen durchgeführt. Das modulare Schulungsprogramm (ModuS) bietet insbesondere für seltene bzw. weniger häufige Erkrankungen ein evaluiertes, qualitätsgesichertes Programm.
Gesundheitskompetenz und Wahlentscheidungen bei öffentlichen Qualitätsvergleichen
Authors: Hensen Peter
Published: March 2017

Gesundheitskompetenz im Sinne einer gezielten Auswahl und Inanspruchnahme von Versorgungsangeboten auf Basis von vergleichenden Qualitätsdaten wird auch als Nutzerkompetenz verstanden. Diese ist auf die Verfügbarkeit, Zugänglichkeit und Qualität geeigneter Informationen angewiesen (Expertenebene), setzt aber ebenso individuelle Wissens- und Handlungsressourcen voraus (Nutzerebene). Für die Vermittlung und Annäherung von Experten- und Nutzerebene wird der Aufbau von institutionellen Schnittstellen in Form von unabhängigen Mediatorsystemen empfohlen.
Leichte Sprache: Verständlichkeit ermöglicht Gesundheitskompetenz
Authors: Maaß Christiane , Rink Isabel
Published: March 2017

Arzt-Patienten-Kommunikation ist Fachkommunikation: Experten kommunizieren mit Laien über einen fachlichen Gegenstand – über Diagnosen und Behandlungsoptionen. Viele Diagnosen stellen für die betroffenen Patienten nicht nur eine emotionale Belastung dar, sondern erfordern zugleich ihre Mitarbeit. Auf der anderen Seite hat in Deutschland ein Personenkreis im zweistelligen Millionenbereich Probleme beim Verstehen insbesondere von fachlicher Kommunikation. Medizinische Fachkommunikation in Leichter Sprache kann hier unterstützend wirken, Kommunikationsbarrieren abbauen und informierte Entscheidungen der Patienten ermöglichen.
Gesundheitskompetenz vernetzen: Qualitätsentwicklung von Online-Multiplikatorenplattformen
Authors: Salaschek Martin , Thaiss Heidrun
Published: March 2017

Die Digitalisierung bringt auch für Leistungserbringer im Gesundheitswesen Chancen und Herausforderungen bei der Förderung der Gesundheitskompetenz mit sich. So können nicht nur Zielgruppen online angesprochen werden, sondern Akteure können sich auch auf Multiplikatorenplattformen vernetzen. Der vorliegende Beitrag nennt Besonderheiten solcher Plattformen und stellt Ergebnisse zu motivationalen Rahmenbedingungen der Plattform-Nutzung vor.
KomPaS: Studie zur Kommunikation und Patientensicherheit
Authors: Horch Kerstin , Firnges Christiane , Starker Anne , Jordan Susanne
Published: March 2017

In der KomPaS-Studie sollen Information und Kommunikation im Gesundheitswesen aus der Sicht der Bevölkerung beschrieben und zentrale Einflussfaktoren ermittelt werden. Im Zentrum stehen die Themen Informationsbedarfe, Gesundheitskompetenz, Patientensicherheit, informierte Entscheidung und ärztliche Beratung. Für die vom Bundesministerium für Gesundheit geförderte Studie ist eine telefonische Befragung von 5.000 Personen ab 18 Jahren geplant.
Aircraft Automatic Control System Failure and Flight Safety
Authors: Šlihta Mareks , Šestakovs Vladimirs , Karunanidhi Ramachandran
Published: March 2017

This article presents a mathematical model estimating the probability of successful completion of the aircraft’s flight in case of aviation equipment failure in flight. This paper shows the relationship between the aircraft’s automatic control system and flight safety. The calculations of probability are made for the successful completion of the flight on Boeing 737 aircraft when the automatic control system has failed.
Dynamic Model of Aircraft Landing
Authors: Suharevs Artūrs , Trifonovs-Bogdanovs Pjotrs , Šestakovs Vladimirs , Mamay Konstantin
Published: March 2017

This manuscript presents a research method that will be used in the development process of avionics equipment. A special device predicting braking and take-off distances will help pilots and provide a complex increase of flight safety and decrease of some types of charges.
Algorithm of Analytical Bank-And-Climb Gyro Unit Without a Heading Gyro
Authors: Trifonovs-Bogdanovs Pjotrs , Levikins Artūrs , Kirillovs Vadims , Zabirov Zarif
Published: March 2017

An analytical bank-and-climb gyro unit supplies the flight crew with information about aircraft angular movement relative to the local vertical. This article describes the particular principles of unit operation providing a step by step explanation of principles governing the operation of the analytical bank-and-climb gyro unit and provides a kinematic scheme of the unit. The article also gives an insight into the occurrence of errors in the bank-and-climb gyro unit as well as explains their significance.
Aviation Crew Recovery Experiences on Outstations
Authors: Gislason Sigurdur Hrafn , Bogdane Ruta , Vasiļevska-Nesbita Inese
Published: March 2017

ACMI flight crews spend considerable time away from home on outstations. This study suggests that this long term stay carries its own considerations in regards to rest recovery with practical implications for Fatigue Risk Management as prescribed by ICAO. Four recovery experiences, Work Detachment, Control, Relaxation and Mastery, are identified and correlated with 28 crew behaviours on base. The results indicate improvement considerations for airline management organizing a long term contract with ACMI crews, in particular to increase schedule stability to improve the crew member’s sense of Control.
Human-In-The-Loop Remote Piloted Aerial Systems in the Environmental Monitoring
Authors: Urbahs Aleksandrs , Visockiene Jurate Suziedelyte , Liu Yen-Chen , Carjova Kristīne , Kravchenko Sergey
Published: March 2017

Paper is related to development of flying robot system. The main objective is to mingle the professional backgrounds in three research directions: development of the aerial vehicle and localization, development of the tele-interaction framework and control system, development of the image fusion system and photogrammetry. Block diagrams give brief description of the systems and sub-systems under the proposed environmental system. Structure of the monitoring UAV adapted for the hand launch given.
Freedom-from versus Freedom-to: A Dialectical Reading of David Foster Wallace’s Infinite Jest
Authors: Bockmann Lars-Frederik
Published: March 2017

This essay submits David Foster Wallace’s major work Infinite Jest, famous for its vehement critique of postmodern culture, to a thoroughly dialectical method of analysis. In contrast to many previous studies of Wallace’s novel, a dialectical approach conceives of postmodernism not as a ‘style’ of writing available among others to an individual author like Wallace but as a socio-cultural dominant to which the text is indissolubly and actively connected. The essay attempts such a ‘totalizing’ reading of Infinite Jest and an assessment of the text’s difference from postmodernism by moving through two distinct horizons of historicizing interpretation. First, the analysis aims to demonstrate that on the level of content the text is governed by a semantic opposition between freedom and value that can be read in terms of the novel’s structuring ideological system. Second, on the level of form, Infinite Jest is analyzed in terms of a formal conflict between postmodern spatiality and a latent utopian impulse mediated by the novel’s incorporation of science fiction elements.
Effects of 12-Week Concurrent High-Intensity Interval Strength and Endurance Training Program on Physical Performance in Healthy Older People
Authors: García-Pinillos Felipe , Laredo-Aguilera José A. , Muñoz-Jiménez Marcos , Latorre-Román Pedro A.
Published: March 2017

García-Pinillos, F, Laredo-Aguilera, JA, Muñoz-Jiménez, M, and Latorre-Román, PA. Effects of 12-week concurrent high-intensity interval strength and endurance training program on physical performance in healthy older people. J Strength Cond Res 33(5): 1445–1452, 2019—This study aimed to analyze the effect of 12-week low-volume high-intensity interval training (HIIT)-based concurrent training program on body composition, upper- and lower-body muscle strength, mobility, and balance in older adults, as well as to compare it with a low-moderate–intensity continuous training. Ninety active older adults were randomly assigned to experimental group (EG, n = 47) and control group (CG, n = 43). Body composition and physical functioning were assessed before (pretest) and after (posttest) a 12-week intervention. A 2-way repeated measures analysis of variance was used to test for an interaction between training program and groups. The time × group interaction revealed no significant between-group differences at pretest (p ≥ 0.05). The group × time interaction showed significant improvements for the EG in body composition parameters (p ≤ 0.05) and physical functioning (muscle strength: p < 0.001; mobility: p < 0.001; and balance: p ≤ 0.05); whereas the CG remained unchanged (p ≥ 0.05). This HIIT-based concurrent training program led to greater improvements in body composition, muscle strength, mobility, and balance in healthy older people than a regular low-moderate–intensity continuous training, despite the reduction in overall training volume.
Efficacy of the Repetitions in Reserve-Based Rating of Perceived Exertion for the Bench Press in Experienced and Novice Benchers
Authors: Ormsbee Michael J. , Carzoli Joseph P. , Klemp Alex , Allman Brittany R. , Zourdos Michael C. , Kim Jeong-Su , Panton Lynn B.
Published: March 2017

Ormsbee, MJ, Carzoli, JP, Klemp, A, Allman, BR, Zourdos, MC, Kim, J-S, and Panton, LB. Efficacy of the repetitions in reserve-based rating of perceived exertion for the bench press in experienced and novice benchers. J Strength Cond Res 33(2): 337–345, 2019—Autoregulation (AR) is the practice of adjusting training variables in response to athlete feedback. One component of AR postulated to enhance resistance training adaptations involves implementing a resistance training–specific rating of perceived exertion (RPE) scale measuring repetitions in reserve (RIR). The purpose of this study was to examine the efficacy of this method using the bench press exercise. Twenty-seven college-aged men were assigned to one of 2 groups based on training age: experienced benchers (EB) (n = 14, training age: 4.7 ± 2.0 years) and novice benchers (NB) (n = 13, training age: 1.1 ± 0.6 years). Subjects performed 1 repetition maximum (1RM) followed by single-repetition sets with loads corresponding to 60, 75, and 90% of 1RM and an 8-repetition set at 70% of 1RM. Subjects reported a corresponding RPE, based on RIR, for every set. Average velocity was recorded for each single-repetition set along with the first and last repetitions of the 8-repetition set at 70% of 1RM. Average velocity at 100% of 1RM in EB was slower (0.14 ± 0.04 m·s−1) compared with NB (0.20 ± 0.05 m·s−1) (p < 0.001). Experienced benchers recorded greater RPE than NB at 1RM (EB: 9.86 ± 0.14 vs. NB: 9.35 ± 0.36) (p = 0.011). No between-group differences existed for average velocity or RPE at any other intensity. Both EB (r = 0.85, p < 0.001) and NB (r = 0.85, p < 0.001) had strong inverse significant correlations between average velocity and RPE at all intensities. Our findings suggest that the RIR-based RPE scale may be an efficacious approach for AR of bench press training load and volume in college-aged men.
Myanmar in 2016
Authors: McCarthy Stephen
Published: March 2017

The new government in Myanmar in 2016 faced many of its predecessor’s challenges; however, some progress was made in policy reversals and legislative reform. Although the government hosted a major ethnic peace conference, violence erupted again in Rakhine State as community tensions transformed into armed conflict. The country experienced more flooding, an earthquake, and a slowing economy locked into falling commodity prices.
Vietnam in 2016
Authors: Coxhead Ian
Published: March 2017

The 12th party congress showed a preference for stability. Vietnam and the US grew closer over trade and China, but the US election results introduced uncertainty. The Vietnamese economy grew steadily despite drought and global economic weakness. Reform of state firms fell behind schedule, productivity growth lagged, and an environmental disaster sparked vigorous dissent.
Cambodia in 2016
Authors: O’Neill Daniel C.
Published: March 2017

The conflict between Prime Minister Hun Sen’s Cambodian People’s Party and opposition leader Sam Rainsy’s Cambodian National Rescue Party continued throughout 2016, with Rainsy remaining in self-imposed exile in France and the government making numerous arrests of opponents who remained in Cambodia. With the 2018 National Assembly elections on the horizon, Hun Sen appeared to be cracking down on and dividing the opposition in an effort to prevent a repeat of the strong CNRP electoral performance in 2013.
Bangladesh in 2016
Authors: SÁez Lawrence
Published: March 2017

The year 2016 was challenging for Bangladesh. Although there are promising signs of a transition toward upper lower-income status, there is sufficient political instability at the margins to warrant concern. The capstone political event was the July terrorist attack in Dhaka, which many feared might represent the first clear metastasized imprint of the Islamic State (ISIS) in Bangladesh.
China in 2016
Authors: Tanner Murray Scot
Published: March 2017

As the next Party Congress loomed in 2017, China’s top leaders in 2016 endorsed President Xi Jinping as the leadership “core,” a move that may allow his further consolidation of political power. The economy grew at a targeted 6.7%. Beijing challenged the new Taiwan administration, and sought to consolidate its muscle-flexing in the South China Sea. The likely direction of US relations under Donald Trump remained uncertain.
“There’s No Solidarity”
Authors: Su Phi Hong
Published: March 2017

The fall of the Berlin Wall in 1989 reunited factions of not just one, but two formerly divided countries: Germany and Vietnam. Utilizing this theoretically unique case of Vietnamese refugee and immigrant resettlement in Germany, I ask: How do ethnic Vietnamese individuals’ perceptions of coethnics complicate or reinforce social divisions? This essay is based on participant-observation in various sites across Berlin and semi-structured, in-depth interviews. In noting how respondents at times naturalize or reject differences among Vietnamese from varying regions of origin and migration streams, I consider how they reproduce coethnic divisions, at times to protect their societal standing in Germany.
Association between neuroendocrine tumors biomarkers and primary tumor site and disease type based on total 68Ga-DOTATATE-Avid tumor volume measurements
Authors: Tirosh Amit , Papadakis Georgios Z , Millo Corina , Sadowski Samira M , Herscovitch Peter , Pacak Karel , Marx Stephen J , Yang Lily , Nockel Pavel , Shell Jasmine , Green Patience , Keutgen Xavier M , Patel Dhaval , Nilubol Naris , Kebebew Electron
Published: March 2017

Objective

To determine the association between neuroendocrine tumor (NET) biomarker levels and the extent of disease as assessed by68Ga DOTATATE PET/CT imaging.

Design

A retrospective analysis of a prospective database of patients with NETs.

Methods

Fasting plasma chromogranin A (CgA), neuron-specific enolase (NSE), gastrin, glucagon, vasoactive intestinal peptide (VIP) and pancreatic polypeptide (PP), and 24-h urinary 5-hydroxyindoleacetic acid (5-HIAA) levels were measured. Correlation between biomarkers and total68Ga-DOTATATE-avid tumor volume (TV) was analyzed.

Results

The analysis included 232 patients. In patients with pancreatic NETs (n = 112),68Ga-DOTATATE TV correlated with CgA (r = 0.6,P = 0.001, Spearman). In patients with multiple endocrine neoplasia type 1 (n = 39),68Ga-DOTATATE TV correlated with glucagon (r = 0.5,P = 0.01) and PP levels (r = 0.5,P = 0.049). In patients with von Hippel–Lindau (n = 24), plasma VIP (r = 0.5,P = 0.02) and PP levels (r = 0.7,P < 0.001) correlated with68Ga-DOTATATE TV. In patients with small intestine NET (SINET,n = 74),68Ga-DOTATATE TV correlated with CgA (r = 0.5,P = 0.02) and 5-HIAA levels (r = 0.7,P < 0.001), with 5-HIAA ≥8.1 mg/24 h associated with metastatic disease with high positive (81.8%) and negative (85.7%) predictive values (P = 0.001).68Ga-DOTATATE TV in patients with NET of unknown primary (n = 16) and those with NET of other primary location (n = 30) correlated with 5-HIAA levels (r = 0.8,P = 0.002 andr = 0.7,P = 0.02 respectively).

Conclusions

Our data supports the use of specific NET biomarkers based on the site of the primary NET and the presence of hereditary syndrome-associated NET. High urinary 5-HIAA levels indicate the presence of metastatic disease in patients with SINET.
MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine
Authors: Smith Bethany , Agarwal Priyanka , Bhowmick Neil A
Published: March 2017

The high degree of conservation in microRNA fromCaenorhabditiselegansto humans has enabled relatively rapid implementation of findings in model systems to the clinic. The convergence of the capacity for genomic screening being implemented in the prevailing precision medicine initiative and the capabilities of microRNA to address these changes holds significant promise. However, prostate, ovarian and breast cancers are heterogeneous and face issues of evolving therapeutic resistance. The transforming growth factor-beta (TGFβ) signaling axis plays an important role in the progression of these cancers by regulating microRNAs. Reciprocally, microRNAs regulateTGFβactions during cancer progression. One must consider the expression of miRNA in the tumor microenvironment a source of biomarkers of disease progression and a viable target for therapeutic targeting. The differential expression pattern of microRNAs in health and disease, therapeutic response and resistance has resulted in its application as robust biomarkers. With two microRNA mimetics in ongoing restorative clinical trials, the paradigm for future clinical studies rests on the current observational trials to validate microRNA markers of disease progression. Some of today’s biomarkers can be translated to the next generation of microRNA-based therapies.
Exposure to 4,4′-methylene bis(2-chloroaniline) (MbOCA) in New South Wales, Australia
Authors: Shankar Kiran , Fung Vivian , Seneviratne Mahinda , O’Donnell Gregory E
Published: March 2017

Objectives

This study was conducted to determine the level of exposure of 4,4′-methylene bis(2-chloroaniline) (MbOCA) in New South Wales (NSW), Australia.

Methods

An integrated occupational hygiene and biological monitoring program were used to assess the workers’ exposure to MbOCA via inhalation, ingestion and dermal contact. This was conducted by personal air monitoring, static air monitoring and surface contamination monitoring of the work environment and biological monitoring of the workers’ exposure to MbOCA at nine workplaces in NSW.

Results

The air monitoring results for MbOCA gave a geometric mean (GM) of 0.06 μg/m3 and a geometric standard deviation (GSD) of 2.70 and a 95% confidence interval of 0.29 μg/m3. The surface contamination in the main work area showed the highest contamination with a GM of 74 ng/cm2 and a GSD of 17 and a 95% confidence interval of 7,751 ng/cm2. Biological monitoring showed a GM of 0.89 μmol/mol cr and a GSD of 11.9 and a 95% confidence interval of 52 μmol/mol cr. This indicated that 13% of the workers were over the Safe-Work NSW Biological Occupational Exposure Limit of 15 μmol/mol cr.

Conclusions

workers’ exposure through inhalation was minimal; however, evidence from biological monitoring of MbOCA suggested that the main contributing factor to exposure was skin absorption. This was attributed to poor housekeeping and inadequate personal protection. Improvements in these areas were recommended, and it was also recommended to improve the awareness of the workers to the adverse effects to their health of exposure to this carcinogen.
Guest Editorial Commentary on the Findings of the GLAGOV Randomized Clinical Trial
Authors: Podolec Jakub ,   Department of Interventional Cardiology, Jagiellonian University College of Medicine and the John Paul II Hospital, Krakow, Poland, Niewiara Lukasz ,   Department of Interventional Cardiology, Jagiellonian University College of Medicine and the John Paul II Hospital, Krakow, Poland
Published: March 2017

Evolocumab – a human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) – significantly reduces low-density lipoprotein cholesterol levels. This agent has been tested in a series of clinical trials, one of which is discussed here: the GLAGOV study. Statintreated patients with coronary disease were treated with evolocumab or placebo with the result that patients in the evolocumab group low-density lipoprotein cholesterol (LDL-C) levels were significantly lower than the placebo group. Athersclerotic plaque regression was noticed in greater number of patients treated with evolocumab compared with placebo (64.3% versus 47.3%). While we await results from large outcome trials on PCSK9 inhibitors, the GLAGOV trial provides interesting findings of clinical advantages that may extend to LDL-C levels as low as 20 mg/dl.
Cardiac Toxicity of Cancer Chemotherapy
Authors: Asnani Aarti ,   Corrigan Minehan Heart Center, Massachusetts General Hospital, Boston, MA, Peterson Randall T ,   College of Pharmacy, University of Utah, Salt Lake City, UT
Published: March 2017

With the aging of the population, the number of patients diagnosed with cancer has grown significantly over the past few decades. In parallel, survival rates have improved due to the increased efficacy and tolerability of cancer treatments. As such, the acute and long-term toxicities of cancer therapies have become increasingly prominent as contributors to morbidity and mortality in cancer survivors. Cardiac toxicity can occur with a broad range of cancer treatments, from conventional cytotoxic agents to newer targeted and immune-based therapies. Common manifestations of chemotherapy-associated cardiotoxicity include asymptomatic left ventricular dysfunction, congestive heart failure, myocardial ischemia, myocarditis, QT prolongation, and arrhythmia. In this review, we will describe antitumor agents that have commonly been associated with an increased risk of cardiac toxicity, with an emphasis on clinical manifestations, underlying mechanisms, and cardioprotective strategies that can be implemented in this setting.
Practical Aspects of Rotor Mapping in Catheter Ablation of Atrial Fibrillation
Authors: Miller John M ,   Indiana University School of Medicine, Indianapolis, IN
Published: March 2017

Historically, pulmonary veins have been the focus of atrial fibrillation (AF) ablation therapy, but it is increasingly being recognized that localized electric rotors and focal impulse sources have a role in maintaining AF. Targeting of these sources using focal impulse and rotor modulation (FIRM)-guided ablation has resulted in elimination of the source and improved long-term outcomes. FIRM uses wide-area mapping of both atria in AF, using commercially-available basket catheters (to provide contact electrograms). However, not all data support the use of FIRM. This paper provides a description of rotor mapping and ablation. In addition, practical strategies for optimizing the technique are discussed, including: catheter positioning; accurate diagnosis of the presence and locations of focal sources; and amount of ablation performed in regions with rotors or foci.
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibition in Patients With or at High Risk of Coronary Heart Disease
Authors: Prejean Shane ,   Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, Brown Todd M ,   Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL
Published: March 2017

Proprotein convertase subtilisin/kexin 9 (PCSK9) is an enzyme that binds and inactivates the low-density lipoprotein (LDL) receptor onhepatocytes, leading to higher levels of serum LDL cholesterol (LDL-C). Individuals with ‘loss of function’ mutations in the PCSK9 gene havelower LDL-C levels and are at decreased risk of coronary heart disease. In light of this, inhibition of PCSK9 activity has become a target forreducing LDL-C levels, with approaches including monoclonal antibodies, antisense oligonucleotides, and RNA interference technology. Twomonoclonal antibodies to PCSK9, alirocumab and evolocumab, have recently been FDA approved. Although large-scale clinical trials to assesscardiovascular outcomes are awaited, reductions in LDL-C levels have been demonstrated, with no increase in muscle-related adverse effects.In addition to these monoclonal antibody approaches, inclisiran – a molecule that inhibits PCSK9 synthesis by RNA interference – is currentlyunder development. Phase 1 and 2 studies indicate an LDL-C-lowering effect comparable to that of monoclonal antibodies, with effectspersisting to as long as 180 days. Phase 3 studies are planned investigating dose administration two to three times per year. The aim of this report is to summarize the role of PCSK9 inhibition in the lowering of LDL-C. Approaches to PCSK9 inhibition are discussed, and an up-todate insight into current developments in the field is provided.
Política sobre Drogas no estado do Espírito Santo: consolidando retrocessos / Drugs Policy in the State of Espírito Santo: consolidating setbacks
Authors: Leal Fabiola Xavier
Published: March 2017

Este artigo tem como objetivo apresentar os dados da pesquisa Políticas de atenção às questões relacionadas ao consumo de álcool e outras drogas no Espírito Santo (ES), efetuada entre os anos de 2012 a 2014, na qual realizou-se um diagnóstico sobre as instituições de tratamento, prevenção, redução de danos e ensino/pesquisa na área de drogas no ES. Realizaram-se entrevistas com os dirigentes das entidades com a aplicação de instrumento de coleta de dados. Observou-se um cenário que aponta para o crescimento de Comunidades Terapêuticas Religiosas, a reafirmação da lógica manicomial expressa nos encaminhamentos recorrentes da quase totalidade dos municípios capixabas para instituições com regime de internação e, sobretudo, a ausência de instituições qualificadas para atender as demandas para tratamento na área de drogas. Assim, nossas reflexões acompanham as reflexões da Luta Antimanicomial e demais movimentos em defesa do SUS no sentido de nos posicionamos contra a implantação de uma “rede paralela” à rede pública de saúde.
Os Desafios de Conciliar Trabalho, Família e Cuidados: evidências do “familismo” nas políticas sociais brasileiras / The Challenges of Conciliating Work, Family and Care: evidence of “familyism” in brazilian social policies
Authors: Moser Liliane , Dal Prá Keli Regina
Published: March 2017

O artigo problematiza as noções de cuidado e de articulação e conciliação entre família e trabalho, com destaque para as políticas de apoio aos trabalhadores e às trabalhadoras com responsabilidades familiares, buscando evidenciar a importância dessa discussão na realidade brasileira. Considera as mudanças ocorridas nas famílias, no mundo do trabalho e suas implicações nas responsabilidades familiares, e aborda as noções de cuidado e de conciliação entre família e trabalho a partir de diferentes perspectivas de análise. A despeito da previsão no sistema legal brasileiro de algumas medidas voltadas à conciliação, destaca-se o alcance limitado e a baixa provisão de serviços de apoio às famílias com responsabilidades familiares.
Renda Mínima de Inserção no Contexto Europeu: a política europeia de inclusão ativa / Minimum Income of Insertion in the European Context: the european active inclusion
Authors: Guilherme Rosilaine Coradini , Reis Carlos Nelson dos
Published: March 2017

Este artigo contempla estudo sobre os programas de Renda Mínima de Inserção-RMI praticados pelos países da União Europeia, especificamente os pertencentes a denominada zona do euro, tendo como intervalo temporal de observação o período 1990-2015. Organiza a sistematização de um ‘mapeamento’ dos referidos programas, no intuito de explicitar as suas singularidades em nível intra bloco econômico, privilegiando algumas dimensões que os estruturam como princípios básicos, critérios à elegibilidade e condicionalidades. Trata-se de uma pesquisa quanti-qualitativa do tipo exploratória, em que o levantamento dos dados se baseia em fontes documental e bibliográfica de procedência nacional e internacional. Epistemologicamente se pauta no método dialético-crítico, em razão de uma opção teórica e da especificidade do estudo que pressupõe a intrínseca contradição entre Estado, mercado e sociedade.
A Produção Social do Espaço/Tempo e os Vazios Urbanos: o caso do Assentamento 20 de Novembro em Porto Alegre / The Social Production of Space/Time and the Urban Voids: the 20 de Novembro Settlement case in Porto Alegre
Authors: Diligenti Marcos Pereira , Dias Maria Alice Medeiros , Teodoro Isadora
Published: March 2017

Localizada na Região Central da Cidade de Porto Alegre, na Rua Dr. Barros Cassal nº 161, a propriedade onde hoje se localiza o Assentamento 20 de Novembro, após décadas de abandono e degradação foi, a partir do início deste século, palco de tensionamento por parte de organizações de  moradores  na luta pela moradia da Região Metropolitana. Com base em pesquisa bibliográfica e documental qualitativa, este artigo propõe a discussão da segregação socioespacial verificada nas cidades submetidas ao modo capitalista de produção do espaço e do tempo urbano. O Assentamento 20 de Novembro é aqui apresentado como situação emblemática, na forma de um estudo de caso, exemplificando a apropriação pelo movimento social de um vazio urbano como ação de resistência contra- hegemônica à financeirização do habitat, aliada à emergência de um significativo protagonismo das camadas populares no exercício de sua cidadania.
Eficácia da técnica de relaxamento com imagem guiada em pacientes oncológicos submetidos a tratamento quimioterápico
Authors: Lufiego Claudia Adriana Facco , Schneider Rodolfo Herberto , Bós Ângelo José Gonçalves
Published: March 2017

Aims: To evaluate the efficacy of guided imagery relaxation in decreasing depression and anxiety levels in cancer patients submitted to chemotherapy.Methods: A nonrandomized clinical trial was performed in male and female patients aged 30 years or older submitted to chemotherapy at a university hospital in Porto Alegre, southern Brazil. The patients were divided into an Experimental Group, which received the intervention (relaxation technique), and into a Control Group, which did not receive it. Twelve-minute guided imagery relaxation sessions were performed for 14 weeks, always during the chemotherapy procedure. In order to evaluate depression and anxiety levels, the Beck Depression Inventory and Beck Anxiety Inventory were applied at baseline and at the end of the study period. The data were analyzed by the EpiInfo7.0 statistical software using Student’s t, Wilcoxon-Mann-Whitney, and Pearson’s chi-square tests. Statistical significance was obtained when p <0.05.Results: A total of 113 participants with a mean age of 51.3 years, among whom 62.8% were female and 72.6% were married, were included in the study. Breast, lung, and intestinal cancers were the most prevalent types of neoplasms. Fifty-seven patients were assigned to the Experimental Group and 56 to the Control Group. There was a decrease in depression and anxiety levels in the Experimental Group, in which depression scores ranged from 17.3±9.04 to 14.5±7.47 (p <0.0001) and anxiety scores ranged from 15.1±8.84 to 12.9±7.58 (p <0.0001). No significant difference was observed in the Control Group between the baseline and final evaluations.Conclusions: The guided imagery relaxation technique was efficacious in reducing depression and anxiety levels in this sample of chemotherapy-treated cancer patients.
PENGEMBANGAN INDUSTRI PERIKANAN DI SEKITAR KAWASAN EKOLOGIS PENTING: STUDI KASUS CILACAP
Authors: Purnomo Agus Heri , Reswati Elly , Hikmah Hikmah
Published: March 2017

Penelitian ini dilakukan pada periode Januari sampai dengan Desember 2003, dengan tujuan mendapatkan pola pengembangan industri yang ramah lingkungan, di lokasi-lokasi dimana fungsi-fungsi ekologis berbenturan dengan potensi industri perikanan yang besar. Ekologis dalam konteks ini mengacu pada fungsi-fungsi pranata alam seperti fungsi suaka satwa langka, pembesaran larva dan anakan ikan dan ekosistem yang unik. Penelitian ini merupakan studi kasus yang mengambil lokasi utama di Kabupaten Cilacap.
PROFIL SOSIAL BUDAYA MASYARAKAT NELAYAN PERAIRAN LAUT DI INDONESIA
Authors: Nasution Zahri , Hartono Tjahjo Tri
Published: March 2017

Penelitian dengan tujuan mendapatkan profil sosial budaya masyarakat nelayan perairan laut di Indonesia telahdilakukan pada tahun 2003
PENGARUH N-3 HUFA PAKAN TERHADAP PERTUMBUHAN BENIH KERAPU MACAN, Ephinepelus fuscoguttatus
Authors: Suwirya Ketut , Giri Nyoman Adiasmara , Marzuqi Muhammad
Published: March 2017

Asam lemak n-3 HUFA adalah esensial bagi ikan-ikan laut. Kebutuhan asam lemak n-3 HUFA pada ikan berbeda menurut jenis dan ukuran ikan
Silicon Nitride (Si3N4) Implants: The Future of Dental Implantology?
Authors: Badran Zahi , Struillou Xavier , Hughes Francis J , Soueidan Assem , Hoornaert Alain , Ide Mark
Published: March 2017

For decades titanium has been the preferred material for dental implant fabrication, with mechanical and biological performance resulting in high clinical success rates. These have been further enhanced by incremental development of surface modifications aimed at improving speed and degree of osseointegration and resulting in enhanced clinical treatment options and outcomes. However, increasing demand for metal-free dental restorations has also led to the development of ceramic-based dental implants, such as zirconia. In orthopedics, alternative biomaterials, such as polyetheretherketone or silicon nitride, have been used for implant applications. The latter is potentially of particular interest for oral use as it has been shown to have antibacterial properties. In this article we aim to shed light on this particular biomaterial as a future promising candidate for dental implantology applications, addressing basic specifications required for any dental implant material. In view of available preclinical data, silicon nitride seems to have the essential characteristics to be a candidate for dental implants material. This novel ceramic has a surface with potentially antimicrobial properties, and if this is confirmed in future research, it could be of great interest for oral use.
PESQUISAS, CONFERÊNCIAS E ARTIGOS EM INFECÇÃO HOSPITALAR: Aspectos abordados pelos enfermeiros
Authors: Moriya Tokico Murakawa , Pereira Milca Severino , Gir Elucir
Published: March 2017

A proposta deste estudo é analisar as pesquisas que versam sobre Infecção Hospitalar, realizadas par enfermeiras, na tentativa de compreender quais aspectos deste tema têm lhes despertado maior interesse. Para tanto, realizamos um levantamento retrospectivo dos trabalhos publicados em Congressos Brasileiros de Enfermagem e periódicos nacionais de Enfermagem no período de 1980 a 1987.
INSTRUMENTO DE CONSULTA DE ENFERMAGEM A PESSOAS COM HIPERTENSÃO ARTERIAL EM TRATAMENTO AMBULATORIAL
Authors: Pierin Angela Maria Geraldo , Car Marcia Regina
Published: March 2017

O artigo enfatiza a importância da atuação do enfermeiro junto a pessoas hipertensas, apresentando um modelo de impresso de consulta de enfermagem utilizado a nível ambulatorial.
AS POLÍTICAS SOCIAIS E DE SAÚDE NO BRASIL: UMA ABORDAGEM HISTÓRICA
Authors: Oliveira Maria Amélia de Campos
Published: March 2017

A autora faz uma retomada histórica das políticas sociais e de saúde no Brasil, procurando correlacioná-las com as transformações no modo de produção de cada período histórico. Busca evidenciar que as políticas sociais representam a administração, através do Estado, dos conflitos de classe e que as políticas de saúde espressam a desigualdade social, manifesta no acesso diferenciado aos serviços de assistência à saúde.
ELABORAÇÃO DE UM MODELO DE FICHA PARA O ACOMPANHAMENTO DA ASSISTÊNCIA DE ENFERMAGEM À PARTURIENTE
Authors: Oliveira Sonia Maria Junqueira V. de
Published: March 2017

A aplicação de um questionário a 47 enfermeiras obstetras forneceu dados para a reformulação da ficha inicialmente proposta para o acompanhamento da assistência de enfermagem à parturiente.
Pirólise de resíduos de borrachas do setor de mineração para a produção de combustíveis: estudos em escala piloto
Authors: Lago Rochel Montero , Gomes Jamerson Peixoto de Matos , Santos Euler José Martins , Costa Luiz Cláudio de Melo , Chaves Luiz Eduardo de Carvalho
Published: March 2017

Resumo Neste trabalho, estudou-se em escala piloto a pirólise de três diferentes rejeitos de borracha do setor de mineração, i.e. peças de moinho de composição nominal de borracha estireno e butadieno (SBR), peneiras e correias transportadoras com composição nominal à base de borracha natural e butadieno (NR/BR) e pneus offroad de composição complexa (mistura de borracha natural, nitrílica, butadieno e estireno-butadieno) em temperaturas de 450, 600 e 800°C. As reações realizadas a 450°C mostraram uma pirólise incompleta, sendo que a 600 e 800°C os rejeitos de borracha se convertem totalmente em três produtos: 15-25% de gás, 42-44% sólido e 34-45% de líquido. Análises por cromatografia gasosa (CG) dos produtos gasosos mostraram majoritariamente a presença de hidrocarbonetos C1-C4 com valores de poder calorífico inferior (PCI) iguais a 8.496 e 7.325 kcal kg-1, similares ao gás liquefeito de petróleo (GLP). Análise dos sólidos obtidos por análise elementar de carbono, hidrogênio e nitrogênio (CHN), espectrômetria de emissão atômica com plasma induzido (ICP-AES) Spectro Ciros CCD para a determinação de enxofre, análise térmica gravimétrica e diferencial (TG/DTA), carbono fixo, cinzas, voláteis mostraram a presença de 72-89% de carbono com 2% de enxofre. Análises dos produtos líquidos por cromatografia gasosa acoplado a espectrometria de massas (CG-EM) indicaram a presença de misturas complexas de hidrocarbonetos majoritariamente até C20. As amostras NR/BR e pneu produzem líquidos com concentração de compostos aromáticos próxima a 50%, enquanto a amostra SBR resulta na formação de um líquido de concentração próxima a 87%. A mistura dessa fração líquida obtida pela pirólise (sem qualquer purificação) com um diesel comercial nas proporções de 0,5, 1 e 3 vol% mostrou que nenhum parâmetro de qualidade de combustível definido pela ANP (Agência Nacional do Petróleo, Gás Natural e Biocombustíveis) foi alterado significativamente.