bluuebunny/crossref_metadata_2025 huggingface dataset:
P02-162 - Escitalopram Treatment of Fibromyalgia: a Pilot Study
Authors: Cetin M.
Published: June 2010

Objective

To assess the efficacy of escitalopram, a selective inhibitor of serotonin reuptake, in the treatment of patients with fibromyalgia.

Methods

Ten patients with fibromyalgia were assessed prior to and after treatment with fixed-dose escitalopram 10 mg/d. Before initiation of pharmacotherapy, patients were interviewed with the Structured Clinical Interview for Axis I disorders in the Diagnostic and Statistical Manual of Mental Disorders, 4th edition. The study lasted for 12 weeks, and patients were evaluated in weeks 4, 8 and 12. The primary outcome measures were the Fibromyalgia Impact Questionnaire (FIQ) total score and pain score. The anxiety and depression levels of the patients were measured with the Beck Depression, the Beck Anxiety, the Hamilton Anxiety, and the Hamilton Depression scales.

Results

There was a significant improvement in the mean intensity of pain (P< 0.01) and in the disability caused by fibromyalgia (P< 0.01) from baseline to week 12 of treatment. The depression and anxiety scores also decreased significantly from baseline to week 12. The improvement in the FIQ scores did not correlate with the decrease of scores in both patient- and physician-rated depression and anxiety inventories. Change in pain scores also was not correlated with the change in depression and anxiety scores.

Conclusions

Escitalopram was quite promising in alleviating the pain and disability associated with fibromyalgia. This effect seems to be independent of its anxiolytic and antidepressant properties.
P02-164 - Vulnerability's Factors of Smoking Addiction in the Medical and Paramedical Staff
Authors: Damak R. , Masmoudi J. , Feki A. , Mnif L. , Haj Kacem H. , Jaoua A.
Published: June 2010

To determine the factors of vulnerability to the addiction to smoking to the medical and paramedical staff and to prevent them.

Patients and methods

Our study concerned 100 medical and paramedical staffs practicing in the HEDI CHAKER HOSPITAL, Sfax

A structured questionnaire was used to collect socio-demographic, somatic, psychiatric and the tobacco consumption data.

We also used Hospital-Anxiety and Depression Scale (HADS) and Rosenberg's self-esteem scale.

Results

The population was consisted of 100 staffs of the health, distributed in two groups

Group 1 (n = 50), regular or occasional smokers

Group 2 (n = 50), no-smoking witnesses

The mean age was 30 years. Sex-ratio (H/F) was 1.

The smokers were single in 60%. They began to smoke in an average age of 16 years. Their motivations to smoke were mainly: curiosity (44%), decreasing stress (28%), searching pleasure (16%) and doing as the others (12%).

The smokers, compared with witnesses, consumed more alcohol and reported more stress factors (divorce of the parents, the frequent quarrels in the family, financial difficulties).

In our study, low self-esteem and anxiety were statistically correlated to the tobacco consumption (p=0.00).

Conclusion

It emerges from this work that the addiction to smoking in the medical and paramedical staff is frequently associated with traumatic events, anxious disorder and low self-esteem.
P02-167 - Cognitive Alexithymia in an Adult Female with Ring Chromosome 21 Syndrome (R(21))
Authors: Egger J. , Verhoeven W. , van Bon B. , Hoischen A.
Published: June 2010

A 30-year-old female patient with moderate mental retardation and minor dysmorphisms was referred for neuropsychiatric examination because of psychotic and autistic symptoms and impulsivity. She was born dysmaturally after an uncomplicated pregnancy. Postnatally, she developed cyanosis, feeding problems and recurrent urinary tract infections. Her developmental trajectory showed delayed milestones, speech retardation and restricted peer interactions resulting in special education from age 9. Behavioural problems because of sensory impairments induced paranoid ideation due to social misinterpretations, increasing from age 18.

At referral, physical investigation revealed mild dysmorphisms, severe hearing loss and visual impairment, oestrogen deficiency, kyphoscoliosis, mild hypotonia and hyperlaxity of joints. Neuropsychological examination disclosed a disharmonic intellectual and social cognitive profile (total IQ: 50) with adequate performal capacities and marked cognitive alexithymia. No formal psychiatric diagnosis could be established. Karyotyping showed a de novo ring chromosome 21: 46,XX,der(21)r(21)(p11q22.3). High resolution array analysis of chromosome 21 demonstrated one interstitial duplication, two interstitial deletions and one terminal deletion.

Ring chromosome 21 syndrome is a rare condition that may occur on a de novo basis or via parental transmission. Major characteristics of the phenotype are vulnerability to infections, mild facial dysmorphisms, infertility and kyphosis. In addition there may be congenital malformations of nearly all organ systems.

The current case report demonstrates the importance of targeted high resolution micro array analysis in order to substantiate the genotype-phenotype correlation in patients with r(21) and stresses the importance of cognitive alexithymia as a potential cause for behavioural problems and psychiatric symptoms in patients with mental retardation.
P02-170 - Opinions of Italian Residents in Psychiatry on Their Training Course
Authors: Giacco D. , Luciano M. , Volpe U. , Fiorillo A.
Published: June 2010

Objectives

To assess trainees’ opinions on the quality of provided educational programs, as recently pointed out in several European countries.

Methods

The opinions of 198 Italian trainees in psychiatry on their training and their future career were assessed by means of the Questionnaire on Training in Psychiatry (QTP).

Results

Recruited trainees were predominantly female (68%), with a mean age of 30.0 (± 3.0) years. Thirty-seven percent of them chose psychiatry because “it has always been a dream”, 20% by chance and 17% because they felt “keen on it”. Seventy-seven percent of residents interviewed would make the same choice again if they could turn back time.

Seventy percent of the respondents were “globally satisfied” with their training, especially in clinical psychiatry, psychopathology and psychopharmacology. Residents reported that training in psychotherapy, in psychiatric rehabilitation and in forensic psychiatry were the most neglected areas in their specialization course. Only 9% of them participated in exchange programs, finding them useful for their professional life and experience.

Conclusions

These results show that Italian psychiatric trainees are globally satisfied with the quality of their training. However, they feel that the training course in some neglected areas, such as psychotherapy, rehabilitation and forensic psychiatry, should be improved, and that exchange programs in other countries should be promoted.
P02-172 - How well Prepared is a Psychiatric Ward for Dealing with a Medical Emergency?
Authors: Gordon C. , Graham J.
Published: June 2010

Objectives

Geographical separation of psychiatric units from general hospitals may significantly delay provision of optimal treatment for patients in a medical emergency. Following a ‘near miss’ event, we explored how well equipped our unit is for managing such cases. Our objectives were: To explore how confident staff are in dealing with medical emergencies

1.

To measure staff confidence levels in emergency care procedures

2.

To evaluate staff orientation by exploring how well staff could locate key equipment

Methods

Distribution of a questionnaire survey asking respondents to rate their confidence in various emergency skills, for example maintaining an airway. Staff were also asked to rate their confidence in being able to locate emergency equipment and medication when necessary. In addition, suggestions for improvement in provision of any aspect of emergency care were sought.

Following this, data collation was performed by various members of the multi-disciplinary team with scrutiny of current practice. Areas of change include layout of emergency trolley, revision of staff induction to emergency equipment and provision of easily accessible protocols for common medical emergencies. Following these changes, the questionnaire will be re-distributed and the datasets compared.

Results

We anticipate that the survey will be completed by February 2010

Conclusions

This investigation will provide very useful, practical data on how well prepared for an emergency a typical psychiatric ward and staff are for providing immediate emergency care. This will have implications for induction and staff training policy, to ensure patient safety and provision of appropriate medical treatment.
P02-177 - Serotonin Syndrom - a Case Report
Authors: Aljukić N. , Hasanović M. , Bećirović E. , Sutović A.
Published: June 2010

Serotonin syndrome is a potentially deadly reaction that occurs as a result of: therapeutic use of medicament, as a consequence of drugs’ interaction or intentional overdosing with medicaments that influence on the serotonin metabolism.

In this paper the authors presented brief theoretical consideration of etiological causes for clinical onset of serotonin syndrome, clinical features of serotonin syndrome and difficulties in discovering the same in clinical practice. Furthermore, diagnostic criteria, differential diagnoses, treatment and prevention of serotonin syndrome were presented.

Authors presented the case report of female inpatient treated in Psychiatry Clinic in Tuzla University Clinical Centre, whose state of somatic deterioration understood originally within the clinical features of basic diseases. Correspondingly, the dose of pro-serotoninergic antidepressant was increased. Subsequently, and timely recognition of serotonin syndrome, and therapeutic corrections of medication, were of great importance in the course of patients’ recovery.
P02-185 - Healthy Siblings of Children with Cancer: the Forgotten Givers
Authors: Karampela K. , Hatira P. , Damigos D.
Published: June 2010

Objectives

To understand how healthy siblings visualize and represent health and disease as conditions affecting them and others in their family. Furthermore, to evaluate the emotional settings following health and disease for healthy siblings, the reasons lead to illness and what could be done to avoid that path. Additionally, this study aims to investigate the parameters that interfere with the physical and emotional living of healthy siblings and finally to access their subjective knowledge on disease and in particular, cancer.

Methods

Fourteen healthy children, aged between 7 and 14, siblings to children diagnosed and receiving treatment for leukemia (acute lymphoblastic & myelogenous leukemia), nephroblastoma (Wilms’ tumor), lymphoma, rhabdomyosarcoma, where evaluated according to the Hatira's Projective Technique.

Results

Analyzing the interviews lead to different kind of responses; some positive but mainly negative ones. The negative reactions addressed emotional instability, rejection, separation, siblings’ rivalry, the medical treatment itself and the fear of death, while positive reactions concerned self-awareness, sensitization, earlier maturing and increased family coherence after the crisis.

Conclusion

The physical relationship between siblings is a special kind of human relationship that can outrun time and crises, even outgrowing in some cases the relationship between parents and their children. On the other hand, it is simultaneously a very fragile and vulnerable relationship, since traumatic experiences such as those arising from childhood cancer interfere with the mental and emotional growing of the healthy brother or sister, causing confusion to the body, mind and soul.
P02-187 - Iranian Nursing Students' Experiences in Psychiatric Unit
Authors: Karimollahi M.
Published: June 2010

Aim

An exploratory study was conducted with the aim of discovering and describing experiences of nursing students during clinical placement in a psychiatric unit in an Iranian hospital.

Method

This hermeneutic phenomenological study was carried out in a psychiatric unit of an educational hospital in Iran. Data were produced with 13 participants using in-depth interviews to detain their full experiences in psychiatric unit. Analysis rooted in the Diekelmann manner facilitated data interpretation and clarification of frequent themes.

Findings

Four correlated themes - Anxiety, Maturation, Routine learning and Enthusiasm were recognized in the data.

Conclusion

These results present exclusive insight for scheduling and applying fitting clinical Education in Iran, especially in psychiatric units. The exploration and description of experiences of the nursing students will help nurse educators plan clinical learning opportunities in such a way that they are less stressful, thus ensuring that nursing students are equipped to utilize themselves as therapeutic instruments.
P02-190 - High Level of TV Viewing is Associated with Silent Inflammation
Authors: Korkeila J. , Markkula J. , Korhonen P.
Published: June 2010

Aims

Mental disorders are associated with many harmful health behaviors such as smoking, abuse of alcohol or drugs, physical inactivity and overweight. Abdominal obesity has been positively associated with depressive symptoms independent of general obesity (BMI). Adult obesity has been associated with depression, especially in women. Recent evidence implies that causal link goes from depression to obesity. This study set out to investigate the relationship between depression, sleepiness, health behavior, BMI and inflammation.

Material & methods

The study based on a cardiovascular risk sample drawn from the participants of a population survey, (aged 45-70) which was carried out in in southwestern Finland. The subjects filled in several internationally known questionnaires: STAI-S (state-anxiety), BDI (depression), EQH5 and RAND-36 (health-related quality of life), Berlin, ESS and PSQI (sleep disorders), smoking and generic measures on health behavior (e.g. physical exercise, time spent watching TV and using PC, intake of calories and fat). Blood samples were drawn from the subjects to measure among other things hsCRP (n=1318).

Results

We found a statistically highly significant correlation between BMI and hCRP (r=0.22, p< 0.001). Total daily minutes watching TV correlated with hsCRP (0.12, p< 0.001). Partial correlation between total minutes spent watching television and hsCRP while adjusting for depression or BMI did not render it the correlation insignificant not diminish its size.

Conclusions

High level of TV use was associated with silent inflammation despite BMI. Heavy use of TV may be an indicator of harmfully increased stress levels.
P02-192 - Increase of Prefrontal Cortex Blood Flow During the Performance of the Original Version Trail Making Test
Authors: Kubo M.
Published: June 2010

Objectives

We measured oxyHb and totalHb in the prefrontal cortex during the performance of original version TMT by multichannel NIRS using sensitive for detecting changes of oxyHb and totalHb.

Methods

Sixteen healthy student volunteers performed four different screens of TMT-A, and then two different screens of TMT-B.

Results

OxyHb increased while in the prefrontal cortex during the performance of TMT-A and TMT-B. The changes were prominent during the TMT performed at first. OxyHb significantly increased in the right lateral prefrontal cortex during TMT-A while it significantly increased in the bilateral prefrontal cortices during TMT-B.

The results suggest that blood flow increases in the prefrontal cortex during the performance of TMT, and that the bilateral prefrontal cortices are involved in the performance of the original version TMT.

Conclusion

We showed an increase of oxyHb during the performance of TMT in the prefrontal cortex. The increase of oxyHb was more prominent in TMT-B than in TMT-A.

The present study suggests that the simultaneous use of the paper version TMT and multichannel NIRS may provide evidence to disclose neuronal mechanisms related to cognitive functions.
P02-196 - Case Report: Behaviour Alteration with Brain Iron Accumulation
Authors: Lazaro M. , Echeverria N. , Rodriguez J.R. , De La Torre F. , Escribano S. , Bango J.I.
Published: June 2010

Objectives

To analyze psychiatric symptoms in relation to a case of Hallervorden-Spatz disease (neurodegeneration with brain iron accumulation (NBIA) or pantothenate kinase-associated neurodegeneration - familial brain degeneration with iron deposition in brain).

Methods

Pubmed revision on behaviour alteration and its relation to brain iron accumulation. Review of patient medical records, including image studies.

Results

A 52-year-old female with diagnosis of mental retardation and psychosis was treated and followed since 1999. Severe behaviour alteration motivated hospital admission in 2009. Over the last two years, the patient had developed progressive dementia, choreoathetosis, mutism, ideomotor apraxia, urinary and fecal incontinence, and corticospinal signs.

A brain MRI (2008) revealed iron deposits in basal ganglia, hypointensity with an area of central hyperintensity (“eye-of-the-tiger”-sign) in both globus pallidi on T2. Based on clinical and MRI findings a diagnosis of Hallervorden Spatz Disease was made.

Classic form of the disease is characterized by early onset and rapid progression, culminating in early death. Atypical disease, as in our case report, has a later onset and more slowly progressive course.

Systemic chelating agents have not proved beneficial. Treatment remains symptomatic. Our patient has experienced a favourable response to low-dose trazodone and quetiapine.

Conclusions

At times, behavioral changes may predate neurologic manifestations, whereas at other times disturbances in mental status and physical functioning may coexist. Among patients with NBIA, those with atypical disease are much more likely to have psychiatric symptoms with cognitive decline. These features present in our case report usually make a difficult and late diagnosis and treatment.
P02-197 - A Link Between Romantic Attachment and Dimensions of Jealousy
Authors: Marazziti D. , Consoli G. , Albanese F. , Catena Dell’Osso M. , Baroni S.
Published: June 2010

Objective

Jealousy and attachment share some characteristics: both can be interpreted as dynamics aimed at maintaining the subjects/partners together, appear to be triggered by the separation from the attachment figure/partner, involve the same basic emotions, such as fear, anger, sadness, and, finally, both they elicit a sense of safety when the other is close and responsive, or the opposite when he or she is distant. Some studies showed that differences in attachment styles seem to influence both the frequency and the patterns of jealousy expression. However, jealousy is a quite heterogeneous phenomenon, even within the normality domain, and it would be more valuable to ascertain the impact of attachment styles on specific jealousy features. The present study explored the possible relationships between romantic attachment and jealousy in 100 healthy subjects.

Methods

The romantic attachment and jealousy were evaluated by means of, respectively, the “Experiences in Close Relationships” questionnaire (ECR), and the “Questionario della Gelosia” (QUEGE).

Results

The ECR anxiety scale was related to all QUEGE dimensions, while the ECR avoidance scale to the self-esteem, fear of loss and suspiciousness dimensions. Individuals with the preoccupied, fearful-avoidant or dismissing attachment styles showed higher scores than secure subjects at all QUEGE dimensions, while dismissing individuals had lower scores at all dimensions.

Conclusions

Taken together, these findings suggest that the two phenomena, attachment and jealousy, are intertwined.
P02-200 - The Beginning of Dual Pathology Psychiatric Inpatient Care Section (UPD)
Authors: Martinez Martinez C. , Gómez Martínez R. , Ortega García M.D. , Díez Garrido L. , Salazar Li C. , Alonso de la Torre M.A. , Rodríguez Campos A. , Rodríguez Carretero G. , Martínez Manjarrés J.D. , Blanco del Valle P. , Agúndez Modino A.
Published: June 2010

Introduction

UPD is a regional referral hospital psychiatric care unit, endowed with multidisciplinary equipment. It provides care to people with light/moderate/severe intellectual incapacity coexisting with mental disease and/or severe behavioral disorders. It offers attention to patients who need a protected therapeutical environment for correcting behavior disorders. It was opened in September 2008.

Objectives

Description of:therapeutic goals, inclusion/exclusion criteria, admission protocol and psychotherapeutic/pharmacological interventions.

Analysis of inpatients's sociodemographic/clinical characteristics and preliminary assessment of therapy goals.

Methodology

Retrospective study(13-month) of patients admitted to UPD of Leon Hospital from its inception to date. Data are collected from medical histories.

Results

47 referrals have been received,5 of them have been rejected not to fulfill criteria. We’ve 16 patients on waiting list.32 incomes have been realized and 22 discharges have occurred.

19 of the incomes correspond to Mild,6 to Moderate,6 to Severe and 1 to Profound mental Retardation.

Regarding co-morbidity:22 patients presented serious behavioral disorder. From this group, 2 met criteria for autistic disorder, 5 had schizophrenia or unspecific psychotic disorders, 5 presented Personality Disorder and one ADHD.

10 patients did’nt present any important behavioral disturbance. From this group 2 were diagnosed with OCD,3 presented problems due to Alcohol and Substance-related Disorders,3 had Psychotic Disorders, one met criteria for Impulse Control Disorder and one presented Mood Disorder.

Before admission, 12 patients resided in specific handicappeds center, 5 intermittently at selected centers and in family, and 15 lived with family.

Conclusions

Psychotherapeutic intervention and treatment were useful in most cases. It was particularly helpful in treatment of behavioral disturbances. Now we must determine effectiveness in maintenance of improvement when they return to their community.
P02-201 - Safety of the Electroconvulsive Therapy-Paliperidone Combination
Authors: Masdrakis V. , Tzanoulinos G. , Markatou M. , Florakis A. , Konstantakopoulos G. , Papadimitriou G. , Oulis P.
Published: June 2010

Objectives

Patients with psychotic or mood disorders often undergo electroconvulsive therapy (ECT) while receiving antipsychotic and/or other pharmacological agents. Paliperidone (PLP) -a benzisoxazole derivative and the principal active metabolite of risperidone- is a second-generation antipsychotic which has been developed in an osmotic controlled-release oral-delivery system. Thus the peak-through fluctuations of its concentration in plasma are minimized, with consequently decreased incidence of side-effects. To the best of our knowledge, there are, as yet, no reports on the safety of ECT-PLP co-administration.

Methods

Nine female inpatients suffering from affective disorders (N=7) or schizophrenia (N=2) underwent ECT while receiving PLP (3-12 mg/d). Patients’ regimen included other psychotropic medications as well (mainly antidepressants and/or antipsychotics). All patients were monitored closely for recovery time, post-ictal delirium, cardiological and EEG status for at least one hour after each ECT session. In addition to their clinical evaluation, patients’ cognitive -especially memory- functioning was regularly assessed by the Mini Mental State Examination. Overall, patients underwent 83 sessions of bilateral ECT.

Results

ECT-PLP combination was well tolerated and even in cases where cognitive side-effects were of moderate severity (three cases; all were also receiving venlafaxine), they were transient.

Conclusions

Although anecdotal and thus in need of replication in well-designed large studies, our preliminary findings suggest that ECT and PLP can be safely combined whenever both indicated.
P02-206 - Multiple Deep Brain Stimulation Targets for Refractory Obsessive Compulsive Disorders
Authors: Moura A. , Cif L. , Gonzalez Martinez V. , Capdevielle D. , Ionita A. , Biolsi B. , Courtet P. , Boulenger J.P. , Coubes P.
Published: June 2010

Obsessive compulsive-disorder (OCD) is a group of highly debilitating condition characterized by intrusive troubling thoughts, repetitive, compulsive behaviors or mental rituals. A notable percentage of patients are refractory to pharmacological treatment and cognitive behaviour therapy. Increasing attention has been paid to the efficacy of Deep Brain Stimulation (DBS) therapies in alleviating pharmacoresistant psychiatric disorders including OCD.

Objectives

The aim of this prospective study was to determine the efficacy of DBS using several targets in a pharmacoresistant OCD population with heterogeneous symptoms.

Methods

Five patients (3 males) have been included in the study. Patients were classified according to their prominent features as follows: contamination/cleaning, symmetry/checking, exactness/counting and forbidden thoughts.

The entire surgical procedure was performed under general anaesthesia. Direct targeting based on stereotactic MRI without microelectrode recordings was done. A combination of two of the following targets was simultaneously implanted for all patients: subthalamic nucleus, accumbens nucleus and bed nucleus of stria terminalis, limbic globus pallidus internus.

Patients were assessed pre-and postoperatively using the Yale-Brown Obsessive Compulsive Scale.

Results

Mean age at surgery was of 42.6±12.68 years. Mean follow-up with DBS was of 21±14.88 months.

Mean preoperative Y-BOCS scores was 31.6±2.70 and of 11±7.97 (p=0,057, Wilcoxon signed Rank test).

Conclusion

Subthalamic nucleus and accumbens nucleus targets seem to be comparable in alleviating several subtypes of compulsions (checking, cleaning, counting) as well as obsessions. Further investigations are required to assess the role of limbic globus pallidus in improving pharmacoresitant OCD. Implanted system was well accepted without triggering new obsessions.
P02-207 - Continuous Performance Test in Iranian Patients Undergoing Hemodialysis
Authors: Najafi M.
Published: June 2010

Objective

Memory and concentration may be affected by hemodialysis in end-stage renal disease. In this study, changes in cognitive function parameters such as attention, impulsiveness, and reaction time were measured and evaluated in the Iranian hemodialysing patients.

Methods

In this analytic observational study, cognitive function of 38 hemodialysis patients was measured before and after hemodialysis sessions using Conners’ continuous performance test.

Results

Mean age of patients was 37.97 ± 12.58 years. There wasn’t any significant difference between numbers of matches successfully recognized, number of Miss Faire and mean of reaction time of those matches successfully recognized before and after hemodialysis. There weren’t any differences between history of hemodialysis and number of matches successfully, matches missed and mean reaction time of matches. Educational level of patients was significant effect on number of Miss Faire during hemodialysis.

Conclusions

It has been concluded that hemodialysis did not have any significant impact on the cognitive function. However, this hypothesis needs to be checked and confirmed by careful selection of patients and other cognitive function tests.
P02-209 - Role of Immune Mechanisms in Formation of Variants of Adaptation in Persons with PTSD
Authors: Nikitina V. , Vetlugina T. , Epanchintseva E. , Semke V.
Published: June 2010

Study involved 102 combatants (mean age 31,78 ± 6,75 years). Clinical dynamics of PTSD brought neurotic (40) and pathocharacterological (62) variants of PTSD. Control group consisted of 80 healthy men. Clinical syndromes of secondary immune deficiency were detected in 51.4% of patients with neurotic version of PTSD and 75.9% with pathocharacterological version. It's in 2 and 3 times higher than in controls. In pathocharacterological variant of PTSD we observed most frequently infection (53.4%) and autoimmune (17.2%) syndromes. In total group of combatants, as compared with control the overall pool of T-lymphocytes (SD2+), mature T-lymphocytes (SD3+), helper / inducer (CD4+), ACSF-activity of leukocytes, elevated number of cells expressing markers of late activation (HLADR+) and the percentage of peripheral lymphocytes, expressing receptors of Fas-readiness to apoptosis (CD95+) reduced. Comparative analysis of parameters of immunity in different variants of PTSD, revealed some differences. Significant features of the immune status in pathocharacterological variant compared with neurotic are significantly lower values of total pool of T-lymphocytes (CD2+) (p< 0,05), number of helpers/inducers (CD4+) (p< 0,05) and number of B-lymphocytes (CD20+) (p< 0,05). Ppathocharacterologically variant (diagnosis with adverse clinical dynamics), as compared with neurotic version of PTSD (more favorable in clinical terms) is characterized by increased frequency of occurrence of clinical signs of immune deficiency with predominance of infectious and autoimmune syndromes, more pronounced disturbances of indices of immunity. This strongly suggests role of immune mechanisms in formation of various variants for adaptation in clinical PTSD.
P02-215 - Influence of Climatic Factors on Mortality of Psychiatric Patients
Authors: Popovic V. , Popovic I.
Published: June 2010

Influence of climatic factors on human’s mental health was research in a lot of studies in the world last years. The aim of this study is identifying a relationship between various climatic factors and the mortality of psychiatric patients in Specialized psychiatric hospital ‘Gornja Toponica’ - Nis, Serbia.

Methodology

Data for our study we used from computer database in our Hospital. We analyzed one-year period. Climatic data we used from Meteorological station in Nis: temperature, pressure, moisture, wind, cloudiness and precipitation (rain, snow). We compared climatic factors in days when patients died and climatic factors in days without deaths in our hospital.

Results

There were 108 died psychiatric patients during the year, average 2 per week. In 11 days there were two or three deaths. 270 days were without deaths. Minimum deaths were in spring (April and May: 4 per month), and maximum were in winter (December and January: 12 per month). Average age of died patients were 70 years old. After analyzing of climatic factors we concluded that quickly changes of weather conditions have a large influence on mortality of psychiatric patients, and only value of climatic factors don't have influence on mortality.
P02-216 - Music Therapy
Authors: Misic P. , Arandjelovic D. , Stanojkovic S. , Vladejic S. , Mladenovic J.
Published: June 2010

Music has been a medium of therapy for centuries, and there are numerous examples of the curative or healing powers of music in the historical records of different cultures. Music therapy is now accepted as a discipline alongside other paramedical professions such as physiotherapy, occupational therapy, speech therapy and psychology in paramedical services and special educational services provided by health and education authorities.

The aim of this work is to summarize the usage of music therapy worldwide.

With certain clinical populations (patients), music therapy has been found to be effective and beneficial.

It is used with individuals of all ages and with a variety of conditions, including: psychiatric disorders, medical problems, physical handicaps, sensory impairments, developmental disabilities, substance abuse, communication disorders, interpersonal problems, and aging. It is also used to: improve learning, build self-esteem, reduce stress, support physical exercise, and facilitate a host of other health-related activities.

For example, research suggests that listening to Mozart’s piano sonata K448 can reduce the number of seizures in people with epilepsy. This has been called the “Mozart effect”.

Also, music therapy can help to ease the isolation of dementia and prevent old people from completely losing touch with their loved ones.
P02-217 - The Study on Family Functioning by Patients and Their Family Members in Schizophrenic, ,Major Depressive and Bipolar Mood Disorders
Authors: Ranjbar F. , Pourafkary N. , Rahmati F.
Published: June 2010

Introduction and objectives

There are some different ideas about family dynamics -particularly schizophrenic, major depressive and bipolar mood disorders- in psychiatric patient's family.

Aims

The aim of this study was to consider therapeutic purposes in Iranian patients.

Methods

90 randomly selected patients with schizophrenic, major depressive and bipolar mood disorders plus a member of their families - 90 people in 3 groups- who were referred to psychiatric hospitals were evaluated by Iranian version of Family Assessment Device (FAD). Statistical analysis was done at the end.

Results

schizophrenic and bipolar patients who had more negative family functioning were compared with depressed patients. Family members of depressed patients had more negative family functioning compared with family members of schizophrenic and bipolar patients. Family members of schizophrenic and depressed patients had more impaired family functioning in comparison with patients.

Conclusions

More negative perception in schizophrenic patients may be related to the nature of illness and their suspiciousness. Due to negative believes in depressed patients they ascribe family problems to themselves. In general, members of these 3 groups of disorders had more pathologic and more negative functioning compared with patients. That could be the result of presence of ill member and tense interactions in these families.
P02-231 - Individuals with Intellectual Impairment and Complex Needs: Current Trends (Policy and Strategic Direction)
Authors: Travers R.
Published: June 2010

Objectives

1.

Inform European colleagues about current transformational changes in the organisation and delivery of care services in England to a vulnerable group of individuals with both intellectual impairment and multiple complex needs.

2.

Compare and contrast English strategic direction /policy with European Union commitments

3.

Stimulate debate on how such trends compare with the experiences of colleagues across Europe.

Methods

Examination of key English policy drivers including:

1.

Valuing People Now (Intellectual Impairment).

2.

New Horizons (Mental Health).

3.

Putting People first (Social Care)

against current European Union commitments

Results

Review of the implications of:

1.

Demographic factors

2.

Economic considerations

3.

Diagnostic uncertainty

4.

Scandals as catalysts

5.

Personalisation

6.

People being cared for away from their home areas

Conclusions

1.

Cost, access and quality considerations are the priority areas under review.

2.

Though care systems vary enormously across Europe, public expenditure as a share of Gross Domestic Product is unlikely to increase in the short to medium term and this irrefutable fact will challenge strategic intentions and citizens’ expectations, especially in England.

3.

Both English and European Union strategic directions/policy contexts could be cynically viewed as being strong on principle and weak on implementation.

4.

There is a profusion and confusion of existing terminology.

5.

For individuals with intellectual impairment and complex needs and for their carers and families, what they all want is more choice, control and flexibility.

6.

Affected individuals in England appear more satisfied with the strategic direction than are their carers and families.
P02-233 - Acute Paranoid Psychosis Due to Past Chronic Mangenese Exposure
Authors: Verhoeven W. , Kuijpers H. , Egger J. , Lenssen P.
Published: June 2010

A male patient aged 49 was referred for evaluation of an acute paranoid psychotic state followed by an apathy syndrome. Since his history, apart from hypertension, did not mention any somatic complaints or psychiatric symptoms, and he had been involved in an adequate professional career as metalworker and welder, MRI- scanning of the brain was performed. There appeared to be bilateral hyperdensity of the globus pallidus, suggestive for chronic manganese (Mn) intoxication. Subsequently, a Mn plasma level of 31 nmol/l (range: 7-20nmol/l) that confirmed the diagnosis.

Mn is a trace element that regulates many enzymes and is essential for normal development and body function. Chronic Mn intoxication has an insidious and progressive course and usually starts with complaints of headache, fatigue, sleep disturbances, irritability and emotional instability. Later, several organ systems may be affected leading to increased heart rate and/or blood pressure, elevated total cholesterol levels, and lowered fertility in males. With respect to neurotoxicity, Mn primarily affects the globus pallidus and the striatum of the basal ganglia, and induces damage to the dopaminergic system. This may ultimately lead to dystonic movements and a parkinsonian syndrome that is dominated by generalized bradykinesia and rigidity.

As to neuropsychiatry, an array of symptoms may develop up to 30 years after intoxication of which gait and speech abnormalities, cognitive and motor slowing, mood changes and hallucinations are the most common. Psychotic phenomena are rarely reported.

In conclusion, subacute psychotic symptoms in the absence of a psychiatric history, may point towards rare occupational diseases.
P02-235 - PER3 VNTR as a Predictor of Sleep and Diurnal Preference in a Romanian Population
Authors: Voinescu B. , Coogan A. , Thome J.
Published: June 2010

Objective

To evaluate whether a variable number tandem repeat (VNTR) in the human PER3 gene is linked with sleep or circadian phenotypes.

Methods

Seventy three people (age: 23-71; 41 males and 32 females) volunteered for this study. They completed a questionnaire containing the Romanian translations of the Composite Scale of Morningness, the Sleep Disorders Questionnaire, the Pittsburgh Sleep Quality Index, the Pittsburgh Insomnia Rating Scale, the Epworth Sleepiness Scale, the Multidimensional Fatigue Inventory, the Alcohol Use Disorders Identification Test and the Beck Depression Inventory II. Genotyping was performed on genomic DNA in blood.

Results

Sixteen subjects had the shorter allele (PER3 4/4), thirty one the longer one (PER3 5/5), while the rest were heterozygote (PER3 4/5). We found no statistically significant differences between the genotypes on any of the scales used.

Conclusions

In this small population, PER3 genotype predicted none of the investigated variables.
P02-236 - The Determined Reasons for Involuntary Hospital Treatment
Authors: Vukic D.
Published: June 2010

The involuntary hospital treatment is presented as one of the most current problem in psychiatry at all, but not enough explored problem in Serbia. In spite of the fact that it has come to important contemporary of psychiatric service, however the number of involuntary hospitalized patients is still on high level - in some countries above 80% in relations to totally number of hospitalized patients. A primary aim of this study was to adjust comparative analysis of determined reasons for voluntary or involuntary hospital treatment of mental ill persons. This study involved 1274 patients which were hospitalized in Special Psychiatric Hospital nearby Nish, during the period of one calendar year. There were 435 voluntary hospitalized patients (34,1 %) and 839 involuntary hospitalized patients (65,9 %). The most often determined reasons for involuntary hospitalizations were: delusions, hallucinations and aggressive behavior.
P02-237 - May Affective Temperaments Influence Quality of Life
Authors: Yazici A.B. , Yazici E. , Aydin N. , Kirpinar I.
Published: June 2010

Objective

Health is not only the absence of disorders also it needs a good feeling of well-being: Quality of life. The relation between QOL and the psychobiology, genetics, development and evolution of thoughts, emotions and temperaments should not be ignored. In this study we investigated how affective temperaments effect quality of life (QOL) in ‘healthy’people.

Methods

72 healthy subjects (33 women, 39 men) with no physical and psychiatric diagnosis assessed with SCID-I are included to the study. The subjects were examined using TEMPS-A for affective temperaments and WHO-QOL Brief for QOL.

Results

Depressive temperament (DT) scores was negatively correlated with psychological and environmental domains of quality of life (p< 0.05) and anxious temperament (AT) was negatively correlated with physical, psychological and environmental domains of QOL (p< 0.05). Marital status was associated with QOL as singles had higher QOL in physical, psychological and environmental domains (p< 0.05). In linear regression analysis with AT and DT and marital status as independent variables; AT scores predicted low QOL in Physical Health and marital status predicted Environmental Health.

Conclusion

DT had significant correlations with psychological and environmental domains of QOL and higher AT scores predicted lower QOL scores in Physical Health so this study suggests that healthy subjects may have lower QOL only due to higher scores in anxious temperament. A clear understanding of the association between Affective Temperaments and QOL may support a step to provide a better well-being in healthy people.
P03-11 - Prevalence of the Metabolic Syndrome in Day Hospital Patients
Authors: Barreiro A. , Arroita A. , Zumarraga M.
Published: June 2010

Introduction

Shizophrenia has traditionally been associated with higher rates of risk factors for cardiovascular disease and the metabolic syndrome, as a consequence of lifestyle habits, impaired access to health care and antipsychotic agents.

Objetive

To determinate the prevalence of metabolic syndrome in patients with schizophrenia who are in Day Hospital regimen in Vizcaya area (Basque Country, Spain).

Method

A cross-sectional study conducted from december 2008 to April 2009, in Zamudio and Barakaldo Day Hospitals (Vizcaya). Metabolic parameters were measured in 67 patients aged 20 to 65, with a diagnosis of schizophrenia. The definition of Metabolic Syndrome, as proposed by the International Diabetes Federation (IDF) was applied.

Results

The analysis of 67 patients showed a prevalence of the metabolic syndrome of 41,79% at baseline. Obesity (49%), insuline resistance or diabetes (37,31%), and dislipemia (41,79%) can all contribute to the metabolic syndrome.

Conclusions

Compared to the general population, our sample of patients with schizophrenia present higher rates of the metabolic syndrome. The psychiatrist should be responsible for the implementation of the necessary screening assessments and referral for treatment of any physical ilness.
P03-13 - Wish to Revenge in Bosnian War Weterans
Authors: Becirovic E. , Avdibegovic E.
Published: June 2010

Objectives

Soldiers as well as civilians have suffered extreme tortures and terror during aggression on Bosnia. We wanted to assess consequences of that kind of war and to find how meny war veterans still have wish to revenge to enemy.

Methods

We used Harvard trauma manual (Bosnia and Herzegovina Version) to assess Posttraumatic Stress Disorder in sample of 105 war veterans. One of items assess wish to revenge.

Results

Results shows that only 7.3% of war veterans without PTSD has wish to revenge and no one of them has it very often. Veterans with PTSD had higher number of wish to revenge. 42.6% of them has wish to revenge and half of that number has very intensive wish. Statistical analysis shows significant difference between those two groups (p< 0,001). Also it is shown that there is positive correlation between diagnosis of PTSD and wish to revenge.

Conclusions

It was expected that high number of war veterans has wish to revenge for that experience. But according to our study there is low number of war veterans that has wish to revenge. It was expected that higher percent of veterans with PTSD has wish to revenge. It was also expected positive correlation between PTSD and wish to revenge.
P02-242 - Restoring of the Reproductive Function as an Important Constituent of the Psychological Condition of Oncological Female Patients
Authors: Bakunina N.
Published: June 2010

Objectives

Estimation of clinical-and-psychological status was conducted among female patients with diagnosis of cervical carcinoma and endometrial cancer. There were 2 sample groups. The first group consisted of 16 patients of early reproductive age from 20 to 35, not having patient parity. Tissue retrieval of ovary with following criopreservation was carried out among the patients of this group during the surgery stage. To restore the hormonal function of the ovary and rehabilitate the reproduction function after finishing of the complex treatment all patients underwent autotransplantation of the unfrozen ovary tissues into the abdominolvesical wall. Rehabilitation of the reproductive function consists of centesis of Graafian follicle, obtaining of the ovule, in vitro fertilization and transmitting of the embryo of the surrogate mother.

Methods

Informal clinical interviewing, MMPI, The State trait Anxiety Inventory, Personality Questionnaire of the Bechterev Institution.

Results

1.

High intensity of anxious reaction in both groups makes it necessary to provide psychological rehabilitations for patients.

2.

Euphoric, balanced and ergopatic Types of Attitude to the Disease have been frequently observed, which presents the picture not characteristic for the oncological profile patients.

3.

The exceeding rates in the scales of neurotic triad observed through the MMPI need adequate correction.

Conclusions

Restoring of the possibility for a woman to enjoy her natural biological function improves the quality of life of such patients. Probably this will also increase the efficiency of the antineoplastic treatment and the life expectancy for patients this oncological patholgy.
P02-247 - Assessing the Functions of Self-Harm Behaviours in a High Secure Hospital Setting for Patients Deemed Dangerous and Severely Personality Disordered
Authors: Gallagher J. , Sheldon K. , Mannion A.
Published: June 2010

Objectives

The present research aims to investigate what purpose[s] self-harm serves for male patients in a dangerous and severe personality disorder unit in Rampton high secure hospital. It is proposed that existing functional models of self-harm should be modified to suit this group due to environmental constraints and features of their diagnoses.

Methods

A model of self-harm was devised from interviews with patients, literature reviews and a pilot review of daily nursing notes, therapy notes and incident reports. The ten proposed functions for self-harm in this population were affect regulation, interpersonal influence, control, sensation seeking, psychosis, feeling generation, self-punishment, anti-suicide, revenge and the expression of aggressive intent. This was applied to data collected from incident reports and daily nursing notes on all incidents (n=386) of self-harm for all current patients (n=53) in the unit in December 2008, in order to establish the nature and context of the incidents, i.e. the location, time and method of self-harm, as well as the function of the behaviour.

Results

The nature and context of self-harm was similar to that in other inpatient and secure settings, except the number of incidents, which did not vary according to time of day. The functions of self-harm were diverse, and there was evidence for those unique to this population.

Conclusions

Future research intends to develop a behavioural classification system for the assessment of motivations for self-harm that can be administered to staff and patients. The clinical impact of this work is discussed.
P02-251 - Comparisonal Investigation of Rap Personality Disorder in Youngster
Authors: Khanmohammadi Otaghsara A. , Homayouni A.
Published: June 2010

Aim

Personality disorder, formerly referred to as a Character Disorder, is a class of mental disorders characterized by rigid and on-going patterns of feeling, thinking, and behavior. The underlying belief systems informing these patterns are referred to as fixed fantasies or “dysfunctional schemata” (Cognitive modules).