bluuebunny/crossref_metadata_2025 huggingface dataset:
O IMAGINÁRIO COMO FORMA DE ENTENDER A CONSTITUIÇÃO DAS CIDADES
Authors: Baptista Carle Cláudio , Segat Flávia
Published: May 2023

As cidades podem ser examinadas sob diferentes perspectivas. O que propomos com o presente artigo é encontrar um caminho de investigação da simbólica expressa na cidade, a partir do contexto do imaginário durandiano. As imagens apresentam o que seus habitantes carregam consigo no espaço urbano e o que o constitui. As conceituações abstratas das cidades são partes de uma constituição maior e mais ampla, qual seja, a da criação a partir do imaginário dos grupos sociais diferentes que se inter-relacionam ao longo do tempo e produzem e reapresentam as práticas de interação com a urbanidade. A perspectiva examinadora reapresentada pelas narrativas de seus habitantes, projetada em exercícios análogos aos da história oral, servem para dar forma na reapresentação do passado e do presente na constituição, reconstituição e reapresentação da memória coletiva dos espaços urbanos. Os caminhos do imaginário possibilitam experienciar as criações orientadas para o viver da sociedade na urbanidade.
Subregional Differences in Medium Spiny Neuron Intrinsic Excitability Properties between Nucleus Accumbens Core and Shell in Male Rats
Authors: Maria-Rios Cristina E. , Murphy Geoffrey G. , Morrow Jonathan D.
Published: May 2023

The nucleus accumbens (NAc) is known for its central role in reward and motivation (Day and Carelli, 2007; Floresco, 2015; Salgado and Kaplitt, 2015). Decades of research on the cellular arrangement, density, and connectivity of the NAc have identified two main subregions known as the core and shell (Záborszky et al., 1985; Berendse and Groenewegen, 1990; Zahm and Heimer, 1990). Although anatomically and functionally different, both the NAc core and shell are mainly comprised of GABAergic projection neurons known as medium spiny neurons (MSNs) (Matamales et al., 2009). Several studies have identified key morphologic differences between core and shell MSNs (Meredith et al., 1992; Forlano and Woolley, 2010) but few studies have directly addressed how core and shell MSNs differ in their intrinsic excitability (Pennartz et al., 1992; O’Donnell and Grace, 1993). Using whole-cell patch-clamp recordings in slices prepared from naive and rewarded male rats, we found that MSNs in the NAc shell were significantly more excitable than MSNs in the NAc core in both groups. In the shell, MSNs had significantly greater input resistance, lower cell capacitance, and a greater sag. This was accompanied by a lower action potential current threshold, a greater number of action potentials, and faster firing frequency compared with core MSNs. These subregional differences in intrinsic excitability could provide a potential physiological link to the distinct anatomic characteristics of core and shell MSNs and to their distinct functional roles in reward learning (Zahm, 1999; Ito and Hayen, 2011; Saddoris et al., 2015; West and Carelli, 2016).
Behavioral and Transcriptome Profiling of Heterozygous Rab10 Knock-Out Mice
Authors: Bunner Wyatt , Wang Jie , Cohen Sarah , Bashtovyy Denys , Perry Rachel , Shookster Daniel , Landry Taylor , Harris Elizabeth M. , Stackman Robert , Tran Tuan D. , Yasuda Ryohei , Szatmari Erzsebet M.
Published: May 2023

A central question in the field of aging research is to identify the cellular and molecular basis of neuroresilience. One potential candidate is the small GTPase, Rab10. Here, we used Rab10+/−mice to investigate the molecular mechanisms underlying Rab10-mediated neuroresilience. Brain expression analysis of 880 genes involved in neurodegeneration showed that Rab10+/−mice have increased activation of pathways associated with neuronal metabolism, structural integrity, neurotransmission, and neuroplasticity compared with their Rab10+/+littermates. Lower activation was observed for pathways involved in neuroinflammation and aging. We identified and validated several differentially expressed genes (DEGs), including Stx2, Stx1b, Vegfa, and Lrrc25 (downregulated) and Prkaa2, Syt4, and Grin2d (upregulated). Behavioral testing showed that Rab10+/−mice perform better in a hippocampal-dependent spatial task (object in place test), while their performance in a classical conditioning task (trace eyeblink classical conditioning, TECC) was significantly impaired. Therefore, our findings indicate that Rab10 differentially controls the brain circuitry of hippocampal-dependent spatial memory and higher-order behavior that requires intact cortex-hippocampal circuitry. Transcriptome and biochemical characterization of these mice suggest that glutamate ionotropic receptor NMDA type subunit 2D (GRIN2D or GluN2D) is affected by Rab10 signaling. Further work is needed to evaluate whether GRIN2D mediates the behavioral phenotypes of the Rab10+/−mice. We conclude that Rab10+/−mice described here can be a valuable tool to study the mechanisms of resilience in Alzheimer’s disease (AD) model mice and to identify novel therapeutical targets to prevent cognitive decline associated with normal and pathologic aging.
Noncoding SNP at rs1663689 represses ADGRG6 via interchromosomal interaction and reduces lung cancer progression
Authors: Lei Xinyue , Tian Xiaoling , Wang Hao , Xu Xinran , Li Guoli , Liu Wenxu , Wang Dan , Xiao Zengtuan , Zhang Mengzhe , Li Mulin Jun , Zhang Zhenfa , Ma Zhenyi , Liu Zhe
Published: May 2023

A previous genome‐wide association study (GWAS) revealed an association of the noncoding SNP rs1663689 with susceptibility to lung cancer in the Chinese population. However, the underlying mechanism is unknown. In this study, using allele‐specific 4C‐seq in heterozygous lung cancer cells combined with epigenetic information from CRISPR/Cas9‐edited cell lines, we show that the rs1663689 C/C variant represses the expression of ADGRG6, a gene located on a separate chromosome, through an interchromosomal interaction of the rs1663689 bearing region with the ADGRG6 promoter. This reduces downstream cAMP‐PKA signaling and subsequently tumor growth both in vitro and in xenograft models. Using patient‐derived organoids, we show that rs1663689 T/T—but not C/C—bearing lung tumors are sensitive to the PKA inhibitor H89, potentially informing therapeutic strategies. Our study identifies a genetic variant‐mediated interchromosomal interaction underlying ADGRG6 regulation and suggests that targeting the cAMP‐PKA signaling pathway may be beneficial in lung cancer patients bearing the homozygous risk genotype at rs1663689.
Potentiation of neuronal activity by tonic GluD1 current in brain slices
Authors: Copeland Daniel S , Gugel Aleigha , Gantz Stephanie C
Published: May 2023

Ion channel function of native delta glutamate receptors (GluDR) is incompletely understood. Previously, we and others have shown that activation of Gαq protein‐coupled receptors (GqPCR) produces a slow inward current carried by GluD1R. GluD1R also carries a tonic cation current of unknown cause. Here, using voltage‐clamp electrophysiological recordings from adult mouse brain slices containing the dorsal raphe nucleus, we find no role of ongoing G‐protein‐coupled receptor activity in generating or sustaining tonic GluD1R currents. Neither augmentation nor disruption of G protein activity affects tonic GluD1R currents, suggesting that ongoing G‐protein‐coupled receptor activity does not give rise to tonic GluD1R currents. Further, the tonic GluD1R current is unaffected by the addition of external glycine or D‐serine, which influences GluD2R current at millimolar concentrations. Instead, GqPCR‐stimulated and tonic GluD1R currents are regulated by physiological levels of external calcium. In current‐clamp recordings, block of GluD1R channels hyperpolarizes the membrane by ~7 mV at subthreshold potentials, reducing excitability. Thus, GluD1R carries a G‐protein‐independent tonic current that contributes to subthreshold neuronal excitation in the dorsal raphe nucleus.
Predicting cellular responses to complex perturbations in high‐throughput screens
Authors: Lotfollahi Mohammad , Klimovskaia Susmelj Anna , De Donno Carlo , Hetzel Leon , Ji Yuge , Ibarra Ignacio L , Srivatsan Sanjay R , Naghipourfar Mohsen , Daza Riza M , Martin Beth , Shendure Jay , McFaline‐Figueroa Jose L , Boyeau Pierre , Wolf F Alexander , Yakubova Nafissa , Günnemann Stephan , Trapnell Cole , Lopez‐Paz David , Theis Fabian J
Published: May 2023

Recent advances in multiplexed single‐cell transcriptomics experiments facilitate the high‐throughput study of drug and genetic perturbations. However, an exhaustive exploration of the combinatorial perturbation space is experimentally unfeasible. Therefore, computational methods are needed to predict, interpret, and prioritize perturbations. Here, we present the compositional perturbation autoencoder (CPA), which combines the interpretability of linear models with the flexibility of deep‐learning approaches for single‐cell response modeling. CPA learns to in silico predict transcriptional perturbation response at the single‐cell level for unseen dosages, cell types, time points, and species. Using newly generated single‐cell drug combination data, we validate that CPA can predict unseen drug combinations while outperforming baseline models. Additionally, the architecture's modularity enables incorporating the chemical representation of the drugs, allowing the prediction of cellular response to completely unseen drugs. Furthermore, CPA is also applicable to genetic combinatorial screens. We demonstrate this by imputing in silico 5,329 missing combinations (97.6% of all possibilities) in a single‐cell Perturb‐seq experiment with diverse genetic interactions. We envision CPA will facilitate efficient experimental design and hypothesis generation by enabling in silico response prediction at the single‐cell level and thus accelerate therapeutic applications using single‐cell technologies.
Decision Tree Prediction Model in Patient Mortality Rate based on Risk Factors
Authors: Handayani Sri , Nurmandhani Ririn , Kusuma Edi Jaya , Wiwoho Sadono
Published: May 2023

The Coronavirus disease (Covid-19) has become a global problem since WHO declared a pandemic in 2020. The number of deaths due to Covid-19 has increased significantly in many countries. This study aimed to implement decision tree modeling to represent the relationship between risk factors and the mortality rate of Covid-19 patients. This study analyzed secondary data of 83,024 Covid patients from January 2020 to June 2021. Data processing used data mining with the decision tree classification method. The results showed that comorbidity is the leading risk factor for death which is then influenced by age. The higher the age group with comorbidities, the higher the risk of death. Suggested that health services can utilize the results of this study to prevent the severity of Covid-19 infection. Such as the development of comorbid awareness programs and community-based education on managing patients with comorbidities.
The Effect of Sansevieria Plant on Particulate Matter 2.5 Levels in Classroom
Authors: Sutrisno Sutrisno , Wiwaha Guswan , Sofiatin Yulia
Published: May 2023

The Poor physical environment is the main cause of acute respiratory infections that result in death in school children aged 5 to 14 years due to exposure to PM2.5 at school. The improvement of the school’s physical environment from high PM2.5 pollution is to involve the school community in planting Sansevieria Trifasciata as a solution to reducing PM2.5 pollution. This study aims to analyze the significance of differences in the physical environmental conditions of the Ciranjang 1 State Elementary School, Cianjur Regency, on the level of respiratory susceptibility of students seen from PM2.5 levels before and after the placement of Sansevieria Trifasciata. The study used 2 test classes and 1 control class. The study duration was 24 hours with two measurements, namely at the pretest and posttest. Data analysis used the Ancova one-way test followed by the Post-Hock test. The placement of 8 pots of Sansevieria Trifasciata was able to absorb PM2.5 compared to 6 pots of Sansevieria trifasciata. There is an effective and significant absorption of PM2.5 pollutants by placing 8 pots of Sansevieria trifasciata plants in a 49m2 classroom, which is 29µgr/m3 on the respiratory vulnerability level of Ciranjang 1 State Elementary School students, Cianjur Regency.
Spatial Analysis of Lymphatic Filariasis Case and Mosquito Resting Place in Rural Area of Brebes Regency, Indonesia
Authors: Siwiendrayanti Arum , Anggoro Sutrisno , Nurjazuli Nurjazuli
Published: May 2023

Brebes Regency is an endemic area of Lymphatic Filariasis (LF) and has the highest number of LF cases in Central Java Province, Indonesia. Despite it is located in the coastal region, which is already known as one of the risk factors of LF, the LF case is distributed more in rural areas, away from the shoreline. Adult mosquitoes need a particular site, called a resting place, to rest after and before biting for a blood meal. The purpose of this study was to analyze spatially the distribution of LF cases and mosquito resting places in three subdistricts whose highest LF case is in the Brebes Regency. The three subdistricts are rural areas. The observed resting places were cattle pens, unmaintained bushes, and maintained bushes. The data of LF patients were obtained from the Health Office of Brebes Regency, which stood at 14 patients. Spatial mapping of LF case and mosquito resting place distribution was composed. 4 patients were located in the mosquito flight radius from unmaintained bushes, 3 patients were located in the mosquito flight radius from cattle pen, and 7 patients were located in the mosquito flight radius from both unmaintained bushes and cattle pen. It indicated unmaintained bushes, together with cattle pen, are the favorable resting place contributing to LF transmission.
Por qué interesa a un agnóstico la filosofía de la religión
Authors: Sádaba Garay J.
Published: May 2023

Bajo Palabra. Revista de Filosofía
La influencia de Husserl y Heidegger en la hermenéutica filosófico-fenomenológica de Paul Ricoeur
Authors: Martín Huete F.
Published: May 2023

El problema de fondo que plantea Ricoeur es ver si se da una oposición entre la hermenéutica del lenguaje religioso, en tanto “hermenéutica de la proclamación o de la palabra Kerigmática”, y la “fenomenología (manifestación) de lo sagrado o también simbólica de lo sagrado”. Adelantando la respuesta de Ricoeur a dicha cuestión es conveniente señalar que lo que la “fenomenología de lo sagrado”, el símbolo, de la “hermenéutica de la palabra” es la condición „lingüística? de esta última. Tal diferenciación tiene unas repercusiones importantísimas cara a la misma delimitación del campo religioso y que ahora conviene aclarar.
Derecho internacional contemporáneo: ¿el imperio de la Ley o la Ley del imperio?
Authors: Álvarez J. E.
Published: May 2023

Introducción. I. El ideal del Derecho: a). Los Estados Unidos y las Naciones Unidas. b). Tratados internacionales de inversión. II. Contra-narrativa: La Ley del Imperio: a). El Consejo de Seguridad: Legislando la hegemonía. b). Inversión Internacional. III. La complejidad de los regímenes internacionales contemporáneos: a). La reacción contra el consejo de seguridad. b). Restricciones del Imperio en las inversiones internacionales. IV. Un acercamiento a la comprensión de „imperio?: a). El imperio antiguo. b). El moderno imperio de la ley. V. Conclusión.
Hannah Arendt y la conquista del espacio: repensar la condición humana
Authors: Pereira Castanheira N.
Published: May 2023

El punto de partida de esta reflexión será una lectura del análisis kantiano del espacio, presente en la sección Die transzendentale Ästhetik, incluida en la obra Kritik der reinen Vernunft, centrándose en dos aspectos fundamentales: por un lado, la comprensión kantiana del espacio como una predisposición por parte del sujeto para la experiencia, anterior a cualquier experiencia particular; por otro lado, la identificación de esa condición subjetiva con la condición humana. Hannah Arendt, en el texto 'The Conquest of Space and the Stature of Man', intenta reflexionar sobre un escenario de apropriacion, por el humano, de las condiciones de posibilidad de la experiencia y de la existencia, que implica un abandono de su condición, tal y como Kant la piensa. Nuestra ponencia intenta mostrar que la reflexión realizada por Hannah Arendt en torno a la conquista del espacio y a la condición humana abre la posibilidad de la fundación de una Ética de responsabilidad con un ámbito alargado.
¿Resulta plausible un juego de lenguaje trascendental?
Authors: Gamero Cabrera I. G.
Published: May 2023

El principal objetivo de este artículo es analizar la propuesta de K. O. Apel, en su obra “La transformación de la filosofía”, donde propone el concepto de juego de lenguaje trascendental como solución a la crisis que vive la filosofía y la política del siglo XX que nos conducirá a la comunidad ideal de comunicación, caracterizada por la ausencia de cualquier tipo de conflicto. Como alternativa al reduccionismo de la teoría de Apel, propondremos un regreso a los hechos, a la vida cotidiana, inspirado en la obra del segundo Wittgenstein.
Tools at the Service of Public Administrations to Fight Digital Gender Inequalities
Authors: Rodríguez Ayuso Juan Francisco
Published: May 2023

This article seeks to highlight how the emergence of the information society and, with it, the New Information and Communication Technologies, despite their benefits, have also brought with them important challenges in the fight against gender discrimination. Moreover, after their consolidation, we can speak of a new digital gender gap that has certainly been intense in rural environments, which are particularly disadvantaged in the implementation of virtual reality. For this reason, mechanisms are established to fight against this new form of discrimination, which should be articulated primarily by the Public Administrations as guarantors of equality among all citizens and the fight for the satisfaction of the general interest, which should only result in the well-being of all. Consequently, the paper begins with a brief introduction that highlights the current context and then goes on to highlight the regulatory guidelines for achieving gender equality in the field of the information society, as well as some relevant initiatives carried out by public bodies, concluding with possible measures to be adopted by the Administrations in favour of gender equality in the digital environment, in which, together with the legal provisions, several public initiatives in favour of the integration of women in the digital environment will also be taken into consideration, trying to reduce digital gender gaps, highlighting, in this respect, the IV Plan for Equal Opportunities between Women and Men 2003-2006 or, of course, the most recent and current, III Strategic Plan for the Effective Equality of Women and Men 2022-2025.
La culpa femenina y la necesidad de productividad en la cuarentena: una reflexión auto etnográfica.
Authors: Moraes Speranza Marina
Published: May 2023

Este ensayo es una reflexión auto etnográfica sobre la culpa femenina en la situación de la cuarentena ocasionada por la pandemia de la covid-19. Atravesando el tema de la culpa a través del concepto de superyó femenino sugerido por Nora Levinton (1999), que impone los mandatos de cuidados a las mujeres, analizo la lógica de la productividad denunciada por Byung-Chul Han (2018a) y otrxs autorxs, que fomenta la creación de los sujetos neoliberales de desempeño, personas que se tornan empresarias de sí mismas, que se exploran voluntaria y apasionadamente. Se trata de una reflexión escrita en primera persona, en tono casi confesional y realizada en el momento específico del confinamiento obligatorio, versando sobre cuestiones como: ¿La culpa es exclusividad de las mujeres, o aparece de una manera diferente en las mujeres? ¿Todas las mujeres son molestadas de igual forma pela culpa? ¿De qué culpas estamos hablando? ¿Qué situaciones pueden reforzar la culpa en la cuarentena? ¿Podremos aprovechar la cuarentena para cambiar cuestiones como la culpa? Es un testimonio desde una perspectiva femenina sobre la culpa, incluyendo el tema de la maternidad, de los cuidados con el cuerpo, la estética, las situaciones de privilegio y vulnerabilidad y la influencia de las redes sociales, particularmente del Instagram, durante la pandemia del coronavirus. Al tratarse de una auto etnografía, rechaza la necesidad de cierre o conclusiones fijas, pero evidencia que la carga de la productividad no es algo que atañe a uno individualmente, sino a la sociedad, de manera general. Así como la culpa ligada a los mandatos de cuidado es algo que sigue en la educación femenina, pese a los avances del feminismo.
Potential Medicinal Plant Species For Fever Used by Minangkabau Ethnic at Nagari Taruang-Taruang, West Sumatra, Indonesia
Authors: Khairiah Ardian , Nisyawati Nisyawati , Silalahi Marina , Altuhaish Adeel Abdulkarim Fadhel
Published: May 2023

AbstractFever is a symptom of illness that is commonly found in the Minangkabau ethnic community. This way, the Minangkabau ethnic community has local knowledge of utilizing plants to cure fever. The purpose of this study was to obtain species of plants used by the Minangkabau ethnic community in the treatment of diseases with symptoms of fever, as well as their potential as modern medicinal ingredients. The research method was carried out by using the open, semi-structural, and participatory observation techniques. Interviews were conducted with 9 key informants selected by purposive sampling and 126 respondents selected by snowball sampling. Data were analyzed qualitatively with descriptive statistic and quantitatively by calculating the Cultural Significance Index (CSI) and fidelity value. The medicinal plants used were 40 species from 22 families. The most used families were Euphorbiaceae (5 species), Musaceae, and Poaceae (each of 4 species), and Rubiaceae (3 species). Cocos nucifera had the highest CSI value, indicating the species was widely used in Minangkabau community. Based on the value of fidelity, 70% value was obtained by 4 plants to treat fever, namely Costus speciosus, Kalanchoe pinnata, Sacciolepeis interrupta, and Enhydra fluctuans. The four plants have the potential to be further developed into modern medicinal ingredients.AbstrakDemam merupakan gejala sakit yang umum ditemukan pada masyarakat etnis Minangkabau. Masyarakat etnis Minangkabau memiliki pengetahuan lokal dalam memanfaatkan tumbuhan untuk penyembuhan demam. Tujuan penelitian ini adalah untuk memperoleh jenis tumbuhan yang digunakan oleh masyarakat etnis Minangkabau dalam pengobatan penyakit dengan gejala demam, serta potensinya sebagai bahan obat modern. Metode penelitian dilakukan dengan teknik wawancara terbuka, semistruktural dan observasi partisipasif. Wawancara dilakukan pada 9 orang informan kunci yang dipilih secara purposive sampling dan 126 orang responden yang dipilih menggunakan snowball sampling. Data dianalisis secara statistika deskriptif dan kuantitatif dengan menghitung nilai kultural (Index of Cultural Significance) dan nilai Fidelitas. Tumbuhan yang obat yang dimanfaatkan sebanyak 40 jenis yang berasal dari 22 suku. Famili terbanyak yang dimanfaatkan yaitu Euphorbiaceae (5 jenis), Poaceae dan Musaceae (masing masing 4 jenis), dan Rubiaceae (3 jenis). Cocos nucifera merupakan tumbuhan obat dengan nilai kultural (CSI) tertinggi. Berdasarkan nilai fidelitas terdapat 4 tanaman yang memiliki nilai 70% dalam penyembuhan demam, yaitu Costus speciosus, Kalanchoe pinnata, Sacciolepeis interrupta, dan Enhydra fluctuans. Keempat tanaman tersebut memiliki potensi untuk dikembangkan menjadi bahan obat modern.
Aktivitas Antimikroba Bakteri Endofit Daun Pegagan (Centella asiatica L.) Terhadap Propionibacterium acnes
Authors: Vernando Riki , Mahyarudin Mahyarudin , Rialita Ambar
Published: May 2023

AbstrakTingginya angka kejadian jerawat dan meningkatnya resistensi terhadap antimikroba memerlukan alternatif pengobatan yang berasal dari bahan alam. Beberapa studi menunjukkan bahwa bakteri endofit tertentu memproduksi senyawa bioaktif yang memiliki efek bagi kesehatan, terutama bakteri endofit yang diisolasi dari tumbuhan obat. Pegagan (Centella asiatica L.) merupakan tumbuhan obat yang mempunyai banyak manfaat seperti untuk mengobati masalah kulit, menyembuhkan luka, serta menjadi agen antimikroba. Penelitian ini bertujuan untuk mengetahui aktivitas antimikroba isolat bakteri endofit daun pegagan terhadap Propionibacterium acnes. Pengujian aktivitas antimikroba dilakukan dengan metode difusi cakram melalui pengukuran diameter zona hambat. Bakteri endofit yang didapat dari penelitian sebelumnya dikarakterisasi berdasarkan ciri-ciri dari morfologi koloni, morfologi sel, dan aktivitas biokimia. Sembilan belas isolat bakteri endofit memiliki aktivitas antimikroba terhadap Propionibacterium acnes, ditandai dengan terbentuknya zona hambat berdiameter antara 11,46–25,34 mm. Dua isolat yang memiliki kemampuan aktivitas antimikroba yang paling besar, yaitu isolat nomor 3 dan 17 dengan hasil identifikasi termasuk ke dalam genus Aeromicrobium. Berdasarkan hasil penelitian dapat disimpulkan bahwa bakteri endofit dari daun pegagan (Centella asiatica (L.) berpotensi sebagai antimikroba terhadap bakteri P. acnes.AbstractThe high prevalence of acne cases and the increasing resistance to antimicrobials requires alternative treatments that originate from natural ingredients. Several studies have shown that certain endophytic bacteria produce bioactive compounds that benefits human health, especially those whom isolated from medicinal plants. Gotu kola or pegagan (Centella asiatica L.) is one of medicinal plant that has many benefits such as treating skin problems, healing wounds, and also known for an antibacterial agent. The aim of the study was to determine the antimicrobial activity of the endophytic bacterial isolates of pegagan against Propionibacterium acnes. The antimicrobial activity test were carried out using the disc diffusion method by measuring the diameter of the inhibition zone within isolate. Endophytic bacteria obtained from previous studies were characterized based on the characteristics of colony morphology, cell morphology and biochemical activity. 19 isolates of endophytic bacteria showed antimicrobial activity against P. acnes, indicated by the formation of inhibition zones ranging from 11.46 to 25.34 mm. Two isolates that had the greatest antibacterial activity, namely isolates number 3 and 17 were identified and belongs to the genus Aeromicrobium. Based on the results of this study, it can be concluded that endophytic bacteria from pegagan (Centella asiatica L.) leaves has potential as an antibacterial agent against Propionibacterium acnes bacteria.
Keanekaragaman Jamur Makro dan Potensinya di Kampung Citlahab, Balai Taman Nasional Gunung Halimun Salak
Authors: Fikri Ahmad Habib Nur , Rosyid Caroline Humaira Rifalina , Mahajarifar Ratna Zahara , Fadlun Fia , Noverita Noverita
Published: May 2023

AbstrakKampung Citalahab termasuk dalam Kawasan Pusat Penelitian Cikaniki yang terletak di wilayah TNGHS dengan kekayaan keanekaragaman hayati yang cukup tinggi, salah satunya jamur makro. Penelitian dilakukan dengan tujuan untuk mendapatkan data keanekaragaman jenis jamur makro di Kampung Citalahab, Kawasan Pusat Penelitian Cikaniki, TNGHS serta untuk mengetahui potensinya. Metode yang digunakan dalam penelitian adalah metode searching per plot di tiga jalur yaitu jalur aliran sungai, jalur hutan, dan jalur pekarangan desa serta dilanjutkan dengan pengambilan sampel gambar menggunakan kamera, pengukuran faktor lingkungan, dan identifikasi sampel. Jamur yang ditemukan sebanyak 614 individu dari 43 jenis yang berbeda. Tingkat keanekaragaman jenis di tiga jalur tergolong rendah sampai sedang, dengan indeks kesamaan tertinggi yaitu 37,21%. Jamur makro yang sering ditemui adalah Microporus xanthopus, Microporus affinis, Xylaria longipes,  dan Auricularia auricula. Beberapa genus jamur seperti Auricularia dan Schizophyllum yang ditemukan di Kampung Citalahab berpotensi sebagai bahan pangan. Sedangkan genus jamur Ganoderma, Xylaria, Microporus, Daldinea, dan Trametes berpotensi sebagai bahan obat-obatan. Masyarakat di Kampung Citalahab belum sepenuhnya memanfaatkan jamur yang tersedia di sana akibat minimnya informasi yang didapatkan oleh masyarakat setempat. AbstractCitalahab's village is one of the Cikaniki Research Station Centers located in the TNGHS area with a considerable wealth of biodiversity, one of which is the macro fungi. Research are conducted with the aim of obtaining data for diversity in the macro types of fungi in the village of Citalahab, the Cikaniki Research Station Center, TNGHS and to discover their potential. The method used in research is the searching per plot on 3 locations of streams, forest trails, and rural garden paths and followed by camera sampling, measuring environmental factors, and sample identification. The fungi found as many as 614 individuals from 43 different kinds. The level of variability in all three pathways is low to moderate, with the highest similarity index being 37,21%. The oft identified macro fungus is Microporus xanthopus, Microporus affinis, Xxylaria longipes, and Auricularia auricula. Some genus of fungi such as Auricularia and Schzophyllum found in the Citalahab village are potential food. While the genus fungi of Ganoderma, Xylaria, Microporus, Daldinea, and Trametes are potentially pharmaceuticals. The people of the Citalahab village have not fully benefited from the local people's lack of information available there.
Adaptabilitas dan Stabilitas Hasil Empat Belas Genotip Padi Gogo Pada Tujuh Lokasi Menggunakan AMMI
Authors: Adi Eko Binnaryo Mei , Wibowo Heru , Indrayani Sri , Sulistiyowati Yuli , Anggraheni Yuliana Galih Dyan , Perdani Ambar Yuswi , Nuro Fiqolbi , Paradisa Yashanti Berlinda , Deswina Puspita , Mulyaningsih Enung Sri , Priadi Dody
Published: May 2023

AbstrakPengujian stabilitas genotip merupakan hal yang penting dalam perakitan varietas padi gogo. Metode pengujian yang sering dilakukan menggunakan analisis ANOVA gabungan yang harus memenuhi normalitas data dan homogenitas ragam. Terkadang data yang diperoleh tidak dapat memenuhi asumsi, sehingga diperlukan analisis alternatif menggunakan metode kualitatif, yaitu Additive Main Effect and Main Interaction (AMMI). Penelitian menggunakan empat belas genotip padi gogo pada tujuh lokasi, dengan rancangan percobaan rancangan acak kelompok. Hasil analisis AMMI1 menunjukkan bahwa didapatkan tujuh genotip dengan nilai rerata produksi di atas rata-rata umum yaitu G29, G31, G33, G34, G35, G37, dan G42 (Inpago 9). Inpago 9 sebagai genotip dengan rata-rata produksi tertinggi di seluruh lokasi. Hasil analisis AMMI2 didapatkan genotip dengan kemampuan adaptasi spesifik lokasi dan beradaptasi pada seluruh lokasi. Dua genotip beradaptasi baik di lokasi Probolinggo yaitu G39 dan G40, sedangkan G29 dan G41 di lokasi Sukadana. Sementara genotip stabil didapatkan tiga genotip yaitu G31, G34, dan G36, namun genotip G36 termasuk genotip dengan produktivitas dibawah rerata genotip pada seluruh lokasi.AbstractGenotype stability is an important factor for varieties development in upland rice. The method for testing stability trial using combine ANOVA with several requirements such as the normality and homogeneity of variance of the data. Sometime to satisfy the assumptions from the acquiring data was not match, so that needed the alternate analysis using qualitative method for stability genotype testing. One of the method is Additive Main Effect and Main Interaction (AMMI). The research was used fourteen upland genotype and seven locations. The result for AMMI1 showed that seven genotype which is have average above the general average are G29, G31, G33, G34, G35, G37, and G42 (Inpago 9). The highest production is achieving by Inpago 9 varieties. While in AMMI2 have two different result. The first result is genotype with specific adaptation and genotype with has general adaptability. Genotype with specific adaptation are G39 and G40 in Probolinggo while G29 and G41 in Sukadana. The second result was genotype with general adaptability or have a good stability are G31, G34, and G36, but for genotype G36 has a poor productivity because the average is below the general average. The result from stability analysis in AMMI2 biplot showed the stability of G31 and G34 has a good stability and higher yield above the average of genotype in all location.
O aggiornamento da teologia matrimonial na Exortação Amoris Laetitia
Authors: Emerim Velho Jonas
Published: May 2023

A família e o matrimônio sempre foram preocupações para a Igreja. Diante da crise hodierna em que vive o matrimônio, busca-se responder como a teologia pode ajudar os casais cristãos a viverem a alegria do amor. Na doutrina matrimonial católica foi predominante a ênfase na procriação, mas, a partir do Concílio Vaticano II, a finalidade unitiva do matrimônio também foi valorizada. A Exortação pós-Sinodal Amoris Laetitia encontra-se em continuidade com a perspectiva do Vaticano II. Assim, neste trabalho, busca-se primeiro estudar o desenvolvimento da teologia matrimonial e o acento dado na procriação; depois, analisa-se a teologia do matrimônio presente na Amoris Laetitia, para, por fim, à luz do documento, indicar caminhos para os cônjuges católicos descobrirem e viverem na alegria do amor.
Oak Tree, Gum Tree
Authors: Gough-Brady Catherine , Rogers Christine
Published: May 2023

In Oak Tree, gum tree, a collaborative video work by award-winning filmmakers Catherine Gough-Brady and Christine Rogers, explores the way that audio-visual material can “embrace the complexity of the world” and “incorporate, within their structures and production processes, multiple voices that “utter” together in the creation of content” (Aston and Odorico, 2018, p. 63). Aston and Odorico use this polyphonic approach as a way of exploring relationships between documentary works and audience. Gough-Brady and Rogers are interested in seeing how this approach can be applied between filmmakers and images themselves. Can images be ascribed what Bennett calls ‘vibrancy’ (2010) and have agency in how they are cut together? How much of this becomes an expression of the filmmaker through the images?
This work was selected for exhibition at the International Visual Sociology Association conference in 2022.
Works cited
Aston, J and Odorico, S. (2018). The Poetics and Politics of Polyphony: Towards a Research Method for Interactive Documentary, Aphaville issue 15, Summer
Trend in hospitalizations due to ambulatory care-sensitive conditions in the Federal District
Authors: Horta Isabel Pintas Marques , Andrade Flávia Reis de , Santos Lorena da Silva Luz , Sousa Naira Pereira de , Lima Luciano Ramos de , Rehem Tania Cristina Morais Santa Bárbara
Published: May 2023

ABSTRACT Objectives: to analyze the trend, according to sex, of Ambulatory Care-Sensitive Conditions in the Primary Health Care of the Federal District, from 2009 to 2019. Methods: ecological trend study using ACSC hospitalization data available in the Hospitalization System of the Single Health System. The Prais-Winsten method was used to calculate the annual rate variation, expressed in percentages. The dependent variable was the logarithm of the rates, and the independent one, the years in the time series. Results: the Federal District registered 2,103,951 general hospitalizations, 16.4% of which were due to Ambulatory Care-Sensitive Conditions. Males had a higher rate of hospitalization in the period, and both sexes showed a stationary trend. Conclusions: the time trend of Ambulatory Care- Sensitive Conditions was stationary, but further studies are necessary regarding primary health care coverage.
Pleasure and suffering of nursing in COVID-19 hospital units: between disenchantment and formation of meanings
Authors: Centenaro Alexa Pupiara Flores Coelho , Andrade Andressa de , Franco Gianfábio Pimentel , Silva Rosângela Marion da , Cardoso Leticia Silveira , Spagnolo Lílian Moura de Lima , Bonow Clarice Alves , Costa Marta Cocco da
Published: May 2023

ABSTRACT Objective: to analyze the experiences of pleasure and suffering of nursing workers in COVID-19 hospital units. Methods: a multicenter, qualitative study, developed with 35 nursing workers from COVID-19 units in seven hospitals in southern Brazil. Data were produced through semi-structured interviews, submitted to thematic content analysis with the help of NVivo. Results: experiences of pleasure were linked to gratification, identification with work content, positive results in care, recognition, integration with the team and personal overcoming. Suffering was revealed in daily life of deaths and losses, feelings of helplessness, team conflicts, institutional demands, professional devaluation. Workers reported disenchantment, but also strengthening the meaning of their work, highlighting frontline impacts on their mental health. Final considerations: in the dynamics between pleasure and suffering in nursing work in COVID-19 hospital units, elements point to the risk of psychological illness.
Gerontecnologia interativa para prevenção de quedas em pessoas idosas: estudo descritivo
Authors: Maia Juliana Cunha , Diniz Jamylle Lucas , Sousa Caroline Ribeiro de , Oliveira Francisco Gerlai Lima , Evangelista Brenda Pinheiro , Coutinho Janaína Fonseca Victor , Marques Marília Braga , Barbosa Rachel Gabriel Bastos
Published: May 2023

RESUMO Objetivos: desenvolver gerontecnologia interativa para prevenção de quedas em idosos no domicílio. Métodos: estudo exploratório e descritivo que consistiu no desenvolvimento da gerontecnologia e avaliação por especialistas e pelo público-alvo. Para avaliação, utilizou-se o Índice de Concordância (IC), considerando valores maiores que 80%. Resultados: elaborou-se a maquete tridimensional virtual por meio do programa SketchUp, com a distribuição dos cômodos e andares, constituindo o Protótipo 1 (P1). O P1 foi avaliado por 54 juízes, e todos apresentaram concordância acima do estabelecido, com IC mínimo de 88% e máximo de 100%, produzindo o Protótipo 2 (P2). Este foi submetido à avaliação por 30 idosos participantes de instituição filantrópica. Em todos os itens, o IC variou de 83% a 100%, resultando na versão final. Conclusões: o produto desta pesquisa se revela como ferramenta inovadora e cientificamente fundamentada visando à prevenção de quedas em pessoas idosas.
EVOLUTION OF COMPETITIVE AEROBICS MOVEMENTS BASED ON AESTHETICS
Authors: Liyuan Liu
Published: May 2023

ABSTRACT Introduction: Competitive aerobics is used mainly in the physical education of students in school period. In detriment of the physical value, the aesthetic factor is often neglected, and the analysis of the evolution of its movements can favor the development of this factor. Objective: Explore the evolution of competition aerobics movements based on the aesthetics of the movements. Methods: First, this paper discusses the scoring rules of competition aerobics over the years, using methods from the literature and image data. Next, athletes and coaches were asked to fill out and rate the weight score to analyze the value and scoring rules of competitive aerobics. Results: Aerobics in the competitive world has become increasingly mature, and the scoring rules have been more detailed and targeted. The most basic skills such as movement, strength, aesthetics, and more are the ongoing focus of scoring and specific training. Conclusion: Coaches and athletes must combine the evolution of current competitive aerobic movements, establishing a good foundation with precautions in synergy with the strengthening combination of basic training and scientific research. These are essential features for athletes to gain more scoring advantages in the competitive environment to improve their results in aerobic competitions. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
O que falar em esperanto quer dizer: Revisitando políticas prefigurativas, movimentos sociais e as novas esquerdas
Authors: Fians Guilherme
Published: May 2023

Resumo Desde a primeira metade do século XX, um coletivo de esquerda de Paris organiza encontros semanais para debater política a partir de perspectivas progressistas diversas. Curiosamente, esses debates são realizados em esperanto, uma língua construída para combater rivalidades nacionalistas e estimular a comunicação internacional. A partir de uma etnografia desse grupo de debates, este artigo nos convida a repensar a forma como a antropologia tem usado o termo prefiguração como uma categoria classificatória para distinguir as práticas políticas da new left daquelas das velhas esquerdas. Examinando como o esperanto foi historicamente rotulado como um projeto universalista, mostro como a perspectiva da prefiguração nos permite salientar o uso cotidiano desta língua na criação de espaços horizontais de coprodução de conhecimento político entre ativistas. A partir disso, argumento que o uso de prefiguração como um atalho para distinguir e tipificar movimentos sociais não só é etnograficamente contraprodutivo, como também nos leva a negligenciar as convergências que novas e velhas esquerdas muitas vezes buscam construir para enriquecer seus diálogos e suas lutas coletivas.
De cosas sagradas, tabúes y ortopraxis. el concepto de lulik en Timor-Leste
Authors: Fidalgo-Castro Alberto , Alonso-Población Enrique
Published: May 2023

Resumen En este artículo se examinan los usos y significados del concepto de lulik en el Timor-Leste contemporáneo a partir de los análisis que del mismo han realizado autores de la lingüística y, especialmente, la antropología. En lo tocante específicamente a la antropología, tenemos en cuanta las definiciones que se han hecho del concepto a partir de aproximaciones teóricas de raíz durkheimianas y del giro ontológico. A la luz de la revisión de la literatura sobre el asunto, así como de los datos presentados mediante un estudio de caso etnográfico, evaluamos la pertinencia de estas definiciones y proponemos una interpretación alternativa. Frente a los aportes realizados por otros autores, proponemos que lo lulik, para los timorenses, remite a una tipificación del modo correcto en que deben ser conducidas las relaciones en que las personas pueden verse envueltas en el discurrir de su vida social.
Transfer of knowledge of retirement workers in a higher education institution
Authors: FOSSATTI EMANUELE CANALI , MOZZATO ANELISE REBELATO
Published: May 2023

Abstract We sought to understand the importance and contribution of knowledge transfer (KT) of workers in the retirement phase in a higher education institution (HEI). Such research is justified by the fact that KT in retirement is approached by different areas but with little emphasis on administrative sciences. A qualitative case study was carried out based on the theoretical framework of knowledge creation and transference, in which retired workers and managers and young workers participated. Semi-structured interviews and focus groups were carried out with the participation of 32 people and non-participant observation with about 260 workers. Data were organized with the support of NVivo®11 software, triangulated, and analyzed using content analysis. It is stated that KT contributes to improve work relationships and bring people together, acquires a greater degree of autonomy and recognition, perceives opportunities for professional and personal growth, and contributes to the HEI since the institutional history is valued, processes are improved, organizational costs are reduced, and the organizational climate is optimized. It is concluded that different knowledge is important for HEIs and the people who are part of them, and the need to implement actions is highlighted so that knowledge is not lost when the worker retires.
Frames de uma violência: uma leitura sobre as pressões para a inclusão da pauta da violência contra as mulheres nas políticas públicas brasileiras
Authors: VENTURA YOHANA WIHBY , MENDONÇA PATRÍCIA MARIA EMERENCIANO DE , BRIGAGÃO JACQUELINE ISAAC MACHADO
Published: May 2023

Resumo O objetivo deste artigo é identificar e analisar as frames mobilizadas pelos movimentos feministas para tratar da violência contra as mulheres, bem como discutir suas influências nas políticas públicas. O referencial teórico e metodológico é o das frames (Snow & Benford, 1992). O corpus de pesquisa constitui-se de matérias publicadas nos jornais Folha de S. Paulo e O Globo, em períodos de tempo relacionados a três ações estatais de combate à violência contra a mulher: i) criação das delegacias da mulher, em 1985; ii) estabelecimento dos juizados especiais criminais, em 1995; e iii) aprovação da Lei 11.340 de 2006 (Lei Maria da Penha). Os resultados indicam que, ao longo dos períodos analisados, uma master frame, “violência contra a mulher”, ressoou na opinião pública e fez esta questão ser reconhecida como um problema pelo Estado, que estabeleceu medidas para seu enfrentamento.
Youth, dispositional heritage and situated learning: proposition of a theoretical model for research
Authors: MORAES JHONY PEREIRA , COSTA SILAS DIAS MENDES , HELAL DIOGO HENRIQUE
Published: May 2023

Abstract This theoretical essay links the discussion between popular media, dispositional heritage, and situated learning, proposing a theoretical model for future research. It is suggested that the dispositional heritage of young people from popular backgrounds (inclinations, behaviors, and social practices) is forged from individual and contextual trajectories and implies the process of situated learning and socialization. The proposal contributes to understanding youth from a sociological perspective and social practices, unlike research conducted within the administration mainstream, which tends to focus on professional training and the insertion of young people into the job market based on organizational behavior. After connecting the concepts, a theoretical model is suggested that can guide empirical studies. Finally, some possibilities for conducting this research are presented.
Horizontes de decolonização em marketing: uma proposta com base na crítica à colonialidade da teoria da globalização de mercados
Authors: FERREIRA MÍRIAM DE SOUZA , HEMAIS MARCUS WILCOX
Published: May 2023

Resumo As teorias mais reconhecidas em marketing foram, em sua maioria, escritas por autores do norte global, que foram reverenciados na área por seus ideais. Entre estes, um que merece destaque é Theodore Levitt, com a teoria da globalização de mercados, que é considerada relevante até os dias atuais. Todavia, ao analisar essa teoria e as interpretações feitas a seu respeito por meio de uma perspectiva decolonial da América Latina, percebe-se o quanto ela reproduz a colonialidade. Assim, este artigo buscou analisar, segundo a perspectiva decolonial, com particular atenção ao conceito de colonialidade do poder - e suas derivações, a colonialidade do saber e a colonialidade do ser -, como a colonialidade se faz presente na teoria da globalização de mercados desenvolvida por Theodore Levitt. Tal teoria reitera uma assimetria racial entre povos, posiciona-se como uma perspectiva epistemológica superior e universal e promove uma convergência para formas de Ser associadas ao mundo eurocêntrico. Contudo, sabendo que esta é apenas uma entre outras teorias que compõem o marketing e que reverberam a mesma lógica colonial, propõe-se aqui uma descolonização do marketing no Brasil. Para tanto, sugere-se a incorporação dos pensamentos de autores como Lélia Gonzalez e Ailton Krenak, que debatem criticamente questões relacionadas com a globalização, o capitalismo e mercados. A utilização de conhecimentos subalternizados exteriores à área é uma ousadia teórica necessária para construir uma disciplina do marketing menos assimétrica e mais conscientemente orientada para lidar com as complexidades e os desafios desse contexto.