bluuebunny/crossref_metadata_2025 huggingface dataset:
PERCEPTIONS, PROFITABILITY AND DETERMINANTS OF GRANULATED CASSAVA PACKAGING IN KUMASI METROPOLIS, GHANA
Authors: Tham-Agyekum Enoch Kwame , Nimoh Fred , Boakye Dora , Yeboah Abednego , Abubakar Umar Abdul Baqi
Published: February 2024

Packaging does not only protect a product but also provides directions for using the product, as well as relevant information about its content and nutritional value. This study was undertaken to assess Granulated Cassava (Gari) sellers’ perception, profitability and determinants of packaging in Ashanti Region. The study area was purposively selected because of the active participation and contribution of marketing activities. A structured questionnaire was administered in the form of interview to obtain primary data from the respondents. Data was generated using binary and multinomial logit regression model and Garret ranking technique. The results showed that there is 0.11% difference in the gross margin of both ventures which is also statistically significant at 1%. Years of education, legal requirement, and durability of the packaging material and cost of packaging material were the significant factors that influence sellers’ choice of packaging. Lack of technical know-how, cost of capital equipment and lack of knowledge on packaging equipment and/or material were the most limiting constraints affecting Gari packaging. The study recommends that investors should invest in the Gari packaging business since it has a relatively higher rate of returns as compared to the unpackaged one.
Youth Heavy Metal Bands in Morocco: Resistance and the Struggle for Change
Authors: El Harrami Said , Yachoulti Mohammed
Published: February 2024

In Morocco, Metal is a controversial genre of youth music that has usually been misinterpreted, marginalized and stigmatized by many individuals due to its transgressive sound, lyrical contents and visual codes.  In this regard, the purpose of this paper is to explore the specific lyrical themes of Moroccan Metal bands concerning elements of symbolic transgression and musical activism. It also aims to the main motivations that push these bands to produce and sustain their musical discourse taking into account the conservative nature of the Moroccan context. Using both content analysis and semi-structured interviews, the paper concluded that despite the severe cultural challenges that surround their socio-cultural condition, the artistic participation of Moroccan Metal bands has not just allowed them to gain support from their subculture but also made them impose themselves as leaders of culture of courage. By tracing the Moroccan Metal bands’ artistic engagement and commitments, this paper will bring to light the cultural sociology and multi-dimensional nature of Metal narratives in Morocco and the challenges that shape its existence. It also provides an interesting account for students and academics concerned with cultural minorities, literature and arts-related topics about the nature of content produced by this minority as a reference.
Suspicions of Occult Medicine Murders in the Context of Democratic Elections in Contemporary Côte d’Ivoire
Authors: Ouattara Syna
Published: February 2024

The article contributes to contemporary discourses on so-called occult medicine practices and the associated human murders within the context of democratic elections in Côte d’Ivoire. The study is grounded in anthropological fieldwork conducted in Abidjan from 2018 to 2020. Additionally, information on occult medicine murders from local and international media has been gathered to enrich the reflections further. The study reveals that in the prevalent public discourse, politicians are accused of employing occult medicine to enhance their power and ensure their success by collaborating with ritual specialists. The paper argues that, in everyday discourse, occult medicine murders can be perceived as being ontologically motivated.
Optimization of therapeutic drug monitoring of vancomycin in newborns using “Dried Blood Spot” method
Authors: Petrov V. I. , Anikeev I. S. , Zayachnikova T. E. , Strygin A. V. , Kurkin D. V. , Kazmina Yu. S.
Published: February 2024

Therapeutic drug monitoring (TDM) is used to increase the individualization of pharmacotherapy, especially in patient groups with a high interindividual variability in pharmacokinetic (PK) parameters. One of these groups of patients is newborn children, for whom drug therapy, especially drugs with a narrow therapeutic range, causes a few difficulties or cannot be used in principle.

The aim of the work was to develop and validate quantitative HPLC-MS/MS methods for the determination of vancomycin in “dried blood spot” samples using new protocols and comparison of the results obtained with the results in plasma samples using standard sample preparation methods.

Materials and methods. To prepare stock and standard solutions of vancomycin and norvancomycin as an internal standard, dry portions of the corresponding certified standards of vancomycin (Servier, France) and norvancomycin (Augsburg, Germany, purity grade >95.0%) were used. A chromatographic separation of the components was carried out on a Poroshell 120 C18 column (4.6×50 mm, 2.7 µm). When developing conditions for a mass spectrometric detection of the desired substances using the multiple reaction monitoring (MRM) method, precursor ions and their corresponding product ions were determined.

Results. A quantitative HPLC-MS/MS method for the determination of vancomycin in «dried blood spot» samples was developed and validated. A comparison was made between vancomycin concentrations in «dried blood spot» samples and plasma samples. Moreover, more than 95% of the calculated average concentrations are within the limits of d-2s and d+2s, which correspond to the values of –10.2 and 12.2. That confirms the suitability of the developed method for the analysis of patient samples.

Conclusion. The results obtained make it possible for us to recommend the “dried blood spot” method for therapeutic monitoring of vancomycin, additional studies of PK in this group of patients with subsequent use of this drug in newborns and pediatric patients.
Studying the possibilities of pharmacological correction of hypoxia-induced pulmonary hypertension using a phenolic compound with a laboratory cypher KUD975
Authors: Korokina L. V.
Published: February 2024

The aim of our work was to study a pharmacological activity of a selective arginase-2 and thrombin inhibitor from a phenolic compounds group with a laboratory cypher KUD975 on a model of arterial pulmonary hypertension induced by hypoxia.

Materials and methods. To simulate pulmonary hypertension (РН), animals were placed in a normobaric hypoxic chamber and subjected to 5 weeks of hypoxia with an oxygen content of 10% in the air. After 3 weeks of hypoxia, the animals were administered with the test compound KUD975 (intragastrically, at a dose of 2 mg/kg once a day for 2 weeks). L-norvaline (intragastrically, 20 mg/kg) was used as a reference drug. To assess the development and correction of РН, measurements of cardiohemodynamics, analysis of blood gas composition, study of the number of circulating endothelial precursor cells (EPCs), quantitative PCR assessing the expression of mRNA VEGF-R2, SGF-1 (stromal growth factor-1) and MCP-1 (monocyte chemoattractant protein-1). Next, a histological examination of the lungs and heart was performed, the degree of pulmonary edema and the concentration of cardiotrophin-1 and atrial natriuretic peptide were assessed.

Results. The administration of the studied phenolic compound with laboratory cypher KUD975, as well as the reference drug L-norvaline, led to a decrease in the right ventricular systolic pressure against the background of modeling РН. The present study shows a more than twice-fold decrease in the number of circulating (EPCs) in the animals group with modeling a hypoxia-induced circulatory РН (171.3±12.1) in comparison with the group of intact animals (296.1±31.7; p=0.0018). The recovery of EPCs was noted in the animals group administered with KUD-975 and L-norvaline, up to 247.5±34.2 (p=0.0009 compared with a pulmonary arterial hypertension (PAH) and 235.6±36.4 (p=0.008 compared to PAH), respectively. The studied compounds had a protective effect by statistically significantly increasing the expression of VEGF-R2 mRNA and decreasing the expression of SGF-1 mRNA, reducing the lung moisture coefficient and the concentrations of cardiotrophin-1 and atrial natriuretic peptide and preventing vascular remodeling caused by hypoxia.

Conclusion. When studying the pharmacological activity, it was shown that the phenolic compound with the laboratory cypher KUD975 normalizes hemodynamic parameters, reduces the signs of remodeling of the heart and pulmonary vessels and has a pronounced endothelial protective effect on the model of hypoxia-induced РН, and is superior to the activity of the reference drug L-norvaline.
Terpenoids and phenolic compounds as biologically active compounds of medicinal plants with diuretic effect
Authors: Kurkin V. A. , Pravdivtseva O. E. , Zaitseva E. N. , Dubishchev A. V. , Tsibina A. S. , Kurkina A. V. , Pervushkin S. V. , Zhdanova A. V.
Published: February 2024

The aimof the study was to summarize and systematize the literature data, as well as the results of the carried out research in the field of medicinal plants used as diuretics in the Russian Federation and abroad.

Materials and methods. During the search for this review article materials, the abstract databases of PubMed, Google Scholar, as well as the ResearchGate and elibrary.ru were used. The search was carried out according to the publications for the period from 2005 to 2023. The keywords were as follows: herbal diuretics, diuretic drugs, kidney diseases, types of medicinal plant raw materials. The data from the authors’ previous scientific research on the analysis of the diuretic properties of certain types of medicinal plant raw materials, as well as individual substances of a phenolic nature isolated from them (simple phenols, flavonoids), were also reviewed.

Results. It was determined that the diuretic activity of most of the medicinal plants used, is due to such groups of biologically active compounds as terpenoids (essential oils and saponins), simple phenols, flavonoids and anthracene derivatives related to the secondary metabolites. It has been shown that, despite the fact that many herbal diuretics have concomitant anti-inflammatory, antimicrobial, antiviral, antihistamine and other properties relevant from the point of view of etiology and pathogenesis of the disease, it is reasonable to use them as part of collections of medicinal plants and other combined medicinal herbal preparations, as this is in accordance with the global trend. The types of medicinal plant raw materials that can be a promising source of new diuretic herbal medicines, have been examined in this review.

Conclusion. It has been determined that terpenoids and phenolic compounds make the greatest contribution to the manifestation of the diuretic activity of medicinal herbal preparations, among which the greatest structural diversity is noted for flavonoids. It has been established that in the composition of any drug, taking into account the peculiarities of etiology and pathogenesis of the disease, herbal diuretics can be both the main drug and an auxiliary component. The expediency of using medicinal plant raw materials with a diuretic effect as part of collections of medicinal plants and other combined preparations used in the treatment of kidney and urinary tract diseases has been also substantiated.
NEW EXTRACTION METHOD OF ENTOMOPATHOGENIC NEMATODES USING THE BASIC FLOTAC AND THE MINI-FLOTAC TECHNIQUES
Authors: EL KHOURY YARA , SALVEMINI CARLO , TARASCO EUSTACHIO , CRINGOLI GIUSEPPE
Published: February 2024

The FLOTAC basic technique is a recognised method used mainly in the veterinary field to extract parasites from the faeces of animals found in the stomach and intestine. This study is the first application of the FLOTAC and Mini-FLOTAC techniques to extract infective juveniles of entomopathogenic nematodes from infested Galleria mellonella. The EPN used for this purpose was an endemic Italian nematode belonging to the Rhabitidae family Steinernema carpocapsae. Galleria mellonella larvae were infected and extraction was performed a few days after infection using both techniques. A comparison was then made between the two methods. The results showed that infective juveniles could be extracted from the infected larva as early as three days after infection. The difference between the FLOTAC basic technique and the Mini-FLOTAC technique was not significant in the extraction of entomopathogenic nematodes. Due to its sensitivity and operating easiness the Mini-FLOTAC technique is a promising method for the extraction of entomopathogenic nematodes. It allows faster extraction of nematodes from the inhabited soil and insect host than the conventional White trap method. Key Words: Microbial biocontrol, Entomopathogenic nematodes, Nematode extraction, FLOTAC, Mini-FLOTAC
Normális eloszlás vizsgálata: melyik tesztet alkalmazzuk a gyakorlatban?
Authors: Szilárd Pálma Bernadett , Badics Milán Csaba
Published: February 2024

A statisztikában a normális eloszlásnak központi szerepe van. Kutatásunk az alábbi tizenegy normalitásteszt statisztikai erejét vizsgálja: Shapiro–Wilk- (SW-), Shapiro–Francia- (SF-), Filliben- (F-), Kolmogorov–Smirnov- (KS-), Anderson–Darling- (AD-), Kuiper- (K-), Cramér–von Mises- (CvM-), D’Agostino–Pearson- (DP-), Jarque–Bera- (JB-), Khí-négyzet- (CS-) és Vasicek- (V-) teszt. Az összehasonlításhoz öt, a normálistól eltérő eloszláscsoportból generálunk mintát Monte Carloszimulációval: (–∞, ∞) tartójú szimmetrikus és aszimmetrikus, (0, ∞) tartójú, (0, 1) tartójú és kevert eloszlásokból. A makrogazdasági és pénzügyi adatsorok gyakran 100-nál kisebb elemszámú megfigyelést tartalmaznak, új minta nem szimulálható, ezért kutatásunkban a 10, 20, 30, …, 100 elemszámú mintaméretekre fókuszálunk. Az eredmények alapján a (–∞, ∞) tartójú eloszlások esetén a regressziós és a korrelációs tesztek – mint például a Shapiro–Wilk- és a Filliben-próba – statisztikai ereje a legmagasabb. A (0, ∞) és (0, 1) tartójú eloszlásokon a Shapiro–Wilk- és a Vasicek-teszt teljesít a legjobban, míg a kevert a mintákon a Jarque–Bera-próba statisztikai ereje a kiemelkedő. A tanulmányunkban kapott eredmények segíthetnek a statisztikusoknak és az ökonométereknek a megfelelő normalitásteszt kiválasztásában a vizsgált adatgeneráló folyamatról kialakított prior elképzeléseik alapján.
Derechos de los animales. Un desafío para el Derecho, la moral, la política
Authors: Lalatta Costerbosa Marina
Published: February 2024

La reflexión filosófica sobre la justicia para los animales encuentra expresión en una multiplicidad de teorías. Es fundamental la teoría centrada en el sufrimiento y la compasión (desarrollada entre otros por Peter Singer y Carol Adams), la teoría de los derechos de los animales de Tom Regan, la teoría política de Will Kymlicka sobre los derechos de los animales. El artículo identifica tres preguntas abiertas, transversales a las diferentes posiciones que configuran este rico e importante debate. Se trata de la noción de persona, el tema del mal moral gratuito, el presunto principio de reciprocidad entre derechos y deberes. La creencia que subyace al artículo es que un estudio en profundidad de estas cuestiones teóricas podría ser fructífero para consolidar la idea de que la justicia para los animales es un objetivo ineludible para toda democracia.
Desafíos a los que se enfrenta el discurso de los derechos
Authors: Pérez Luño Antonio Enrique
Published: February 2024

A lo largo de su evolución toda teoría suele enfrentarse con determinados retos o desafíos que, acreditan su vitalidad. El discurso de los derechos, en cuanto concepción teórica dirigida a su explicación y fundamentación, no se halla exento de la tarea permanente dirigida a responder a esos retos. En este ensayo se analizan los riesgos que se estiman más decisivos y acuciantes para el discurso de los derechos. Para ello, se estudian tres desafíos actuales a la teoría de los derechos y se sugieren correlativamente, tres respuestas a los mismos. Eleatismo, particularismo y posthumanismo, se consideran los principales retos a los que se enfrenta hoy la reflexión sobre los derechos. La respuesta a esas actitudes se halla constituida por el historicismo, el universalismo y el humanismo.
Menores, privacidad y derechos humanos en la escuela. El caso de Google workplace for education en España
Authors: Rodríguez Prieto Rafael
Published: February 2024

Este artículo analiza la aplicación en la escuela de plataformas privativas de enseñanza, cuyo uso ha tenido un impulso con la pandemia de la COVID19. Google workplace for education se ha considerado una vía eficaz tanto para adaptarse a los retos de la digitalización como para afrontar situaciones ex- traordinarias. El análisis realizado revela una amenaza ligada a la intimidad de los menores. Aplicando análisis heurístico, los resultados muestran la ne- cesidad de efectivizar un principio de cautela tecnológica sobre el uso de estas plataformas en la educación. Se concluye con la necesidad de profundizar en el análisis de las implicaciones para los niños y adolescentes del uso de este soft- ware y la conveniencia de aplicar herramientas libres y abiertas.
Corrado del Bò, La giustizia. Un’introduzione filosófica
Authors: Ansuátegui Roig Francisco Javier
Published: February 2024

Este artículo reseña: Corrado DEL BÒ, La giustizia. Un’introduzione filosófica, Carocci editore, Roma, 2022, 143 pp.
Oscar Celador Angón, Entidades locales y libertad religiosa
Authors: Contreras Mazarío José María
Published: February 2024

Este artículo reseña: Oscar Celador Angón, Entidades locales y libertad religiosa, Ed. Dykinson, Madrid 2023, 214 pp.
Primary Essential Cutis Verticis Gyrata: A Case Report
Authors: Esteban-Zubero Eduardo , Gracía-Muro Cristina
Published: February 2024

N/A.
Studies on the Ground Water Recharge through Rainfall and Artificial Recharge Structures in Selected Dry Well in Ambedkarnagar District (UP), India
Authors: Arpan Sherring Sonveer Singh
Published: February 2024

An experiment was conducted to study the groundwater recharge through rainfall and artificial recharge structures in selected dry well at different locations of Ambedkarnagar District, UP. The results of the study concluded that the autoregressive time series model can be used effectively to predict the pre and post monsoon ground water level the better predictions will help the Farmers and policy makers to optimally utilize the groundwater resources. It is providing the solutions to execute the artificial recharge structure at the appropriate locations with best geological condition to enhance the recharge rate at least cost for control of declining groundwater level. It reveals that the stochastic auto regressive lime series model is an effective tool for management of ground water resource in Ambedkarnagar district of Uttar Pradesh state.
Short-Term Evolution of Provision and Regulation Ecosystem Services in the Early Stage of Farmer Managed Natural Regeneration-Based System in Niger
Authors: Jangorzo Nouhou Salifou , Soufianou Sadda Abou , Mari Ousmane Sami , Issoufou Hassane Bil- ssanou
Published: February 2024

Thousands of hectares have been treated with Farmer Managed Natural Regeneration (FMNR) over many decades to reverse the adverse effects of land degradation. Many studies have attempted to evaluate the effect of this Soil Land Management (SLM) practice a posteriori. The aim of this study is to assess the evolution of Ecosystem Services (ES) in the first stage of FMNR based agroforestry system in Niger. We, therefore, monitored the evolution of Ecosystem services in sixty farmers (30 practicing FMNR and 30 without practicing FMNR) over three years (2017, 2018 and 2019). The year 2017 was considered as the reference year. Provisioning ecosystem services (agricultural production, fire, wood, service wood) and regulating services (Carbone sequestration) where quantified each year from the same farmers and in the same fields. All crop yields were quantified by biophysical measurements using a plot yield (10m x 10m) included in a larger plot (50m x 50m) for dendrometry measurements. Carbone sequestration was measured by soil carbon analysis and allometric equation for vegetation Carbone. The evolution of financial benefit is measured using Cost Benefit Analysis (CBA). The results showed that the increase in yields in FMNR fields compared to non-FMNR fields was not regular for all crops. Furthermore, the FMNR system improves the regulatory service, and hence, it stores a higher amount of organic carbon (605.5 mg / kg) than the systems without FMNR (432.5 mg / kg). The results of the CBA showed that the incremental cost is negative in 2017 but positive in 2018 and 2019. Therefore, the FMNR practice makes farmers wealthier. Soil Land Management Practices are financially profitable when all ecosystem services are quantified and valued.
Sosialisasi dan Penerapan Pembukuan Transaksi Digital Menggunakan Excel pada Anggota dan Bendahara PKK Padukuhan Tritis di Desa Ngargosari
Authors: Swastikasari Adelia , Yendrawati Reni , Kartini
Published: February 2024

In the digital era, there is a push for the community to be able to operate technology. This work program discusses the importance of keeping up with developments in the Digitalization Era. Digitalization brings new challenges and opportunities in terms of transaction accounting. Digital transaction accounting using Excel is considered an effective way to manage financial records. While there are drawbacks to manual accounting, authors aims to provide understanding to the community of Padukuhan Tritis about the use of the internet in PKK activities and introduces digital transaction accounting. Despite limited internet signal issues in Padukuhan Tritis, observation results show progress in using Excel for recording cash and loan transactions. This program is expected to raise awareness among the community about digital systems, especially in finance, and support the PKK treasurer in financial recording.
Computational Model for Analysing the Tooth Deflection of Polymer Gears
Authors: Ignatijev Aljaž , Glodež Srečko , Kramberger Janez
Published: February 2024

A computational model for analysing the tooth deflection of polymer gears is presented in this paper. Because polymer gears have less stiffness compared to metal gears, the proposed approach considers a comprehensive analysis to determine the most suitable numerical model, i.e., the number of teeth that should be modelled. The developed computational model has been evaluated on the spur gear pair, where the pinion made of POM has meshed with a support gear made of steel. Material properties were assigned with linear elastic characteristics for the gear, while the pinion was characterised by hyperelastic properties using POM material. Furthermore, a nonlubricated frictional contact between the gear and pinion was considered in the numerical computations. The computational results that were obtained were compared to the empirical results according to VDI 2736 guidelines. Here, the computational approach showed more accurate results due to the hyperelastic material characteristics of POM. However, VDI 2736 calculation showed the comparability with computational results with a slightly larger deviation at lower loads.
Just-in-Time Fluid Flow Simulation on Mobile Devices Using OpenVisFlow and OpenLB
Authors: Teutscher Dennis , Kummerländer Adrian , Bukreev Fedor , Dorn Marcio , Krause Mathias J.
Published: February 2024

The present state of research in Computational Fluid Dynamics (CFD) is marked by an ongoing process of refining numerical methods and algorithms with the goal of achieving accurate modeling and analysis of fluid flow and heat transfer phenomena. Remarkable progress has been achieved in the domains of turbulence modeling, parallel computing, and mesh generation, resulting in heightened simulation precision when it comes to capturing complex flow behaviors. Nevertheless CFD faces a significant challenge due to the time and expertise needed for meticulous simulation setup and intricate numerical techniques. To surmount this challenge, we introduce paint2sim—an innovative mobile application designed to enable on-the-fly 2D fluid simulations using a device’s camera. Seamlessly integrated with OpenLB, a high-performance Lattice Boltzmann-based library, paint2sim offers accurate simulations. The application leverages the capabilities of the Lattice Boltzmann Method (LBM) to model fluid behaviors accurately. Through a symbiotic interaction with the open-source OpenCV library, paint2sim can scan and extract hand-drawn simulation domains, affording the capability for instant simulation and visualization. Notably, paint2sim can also be regarded as a digital twin, facilitating just-in-time representation and analysis of 2D fluid systems. The implications of this technology extend significantly to both fluid dynamics education and industrial applications, effectively lowering barriers and rendering fluid simulations more accessible. Encouragingly, the outcomes of simulations conducted with paint2sim showcase promising qualitative and quantitative results. Overall, paint2sim offers a groundbreaking approach to mobile 2D fluid simulations, providing users with just-in-time visualization and accurate results, while simultaneously serving as a digital twin for fluid systems.
Mechanical Properties of Lattice Structures With a Central Cube: Experiments and Simulations
Authors: Guo Shuai , Ma Yuwei , Liu Peng , Chen Yang
Published: February 2024

In this study, a new structure is proposed based on the body-centered cubic (BCC) lattice structure: adding a cubic truss in the center of the BCC structure, which is denoted by TLC (Truss-lattice-cube). The different dimensions of the central cube can affect the mechanical properties of the lattice structure notably. With a fixed length (15mm) of a unit cell, the optimal size for the central cube is determined to be 5 mm. Quasi-static compressive tests are performed on specimens made of Polylactic Acid (PLA) using additive manufacturing technology. The deformation characteristics of the new structure is analyzed in detail by experiments and numerical simulations. Compared to the BCC structure, the mechanical properties of the TLC structure are significantly improved. The initial flow stress of the TLC has been increased by 122% at a strain of 0.1; the specific strength has been enhanced by 293% at a strain of 0.5; and the specific energy absorption has been improved by 312% at the strain of 0.6. Printing defects in the lattice structure could deteriorate the mechanical property remarkably. In this work, incorporation of microcracks into the finite element model makes the simulation capture the influence of printing defects and improve the predictive accuracy of simulation significantly.
The Influence of High Dose Parenteral Vitamin C Supplementation on Incidence and Severity of Postoperative Pulmonary Complications after Cardiac Surgery with Extracorporeal Circulation: A Prospective, Randomized, Single-Blinded, Interventional Study
Authors: Kočica Milica Karadžić , Ristić Arsen , Soldatović Ivan , Lazović Dejan , Čumić Jelena , Grujić Miloš , Karan Radmila , Terzić Duško , Palibrk Ivan , Kocica Mladen , Marković Dejan
Published: February 2024

: Cardiac surgery (CS) with extracorporeal circulation (ECC), induces oxidative stress and systemic inflammatory response, which may seriously affect postoperative lung function. We aimed to test if high parenteral (200mg/kg/24h) perioperative (48h) doses of Vitamin C (VitC) may reduce the incidence and severity of postoperative pulmonary complications (PPC) in selected CS patients. Single centered, prospective, randomized, single-blinded, interventional study included 150 patients, assigned to control group A (n=75) and interventional group B (n=75). Group B intraoperatively received 1/4 of the planned daily Vit C dose (200mg/kg/24h), diluted in 10 ml of normal saline, divided into three parts, while Group A received an equal volume of normal saline at the same time frames. After 6 h from the first intraoperative dose, the following regimen was applied: Group B: 200 mg/kg/24h - 30 min i.v. infusion of VitC in 50 ml of normal saline, every 6h, for the next 48h, and Group A: 30 min i.v. infusion of an equal volume of normal saline every 6 hours, for the next 48h. Modified Kroenke’s score was used to determine the incidence and severity of PPC. The overall incidence of PPC was 36.7% and was significantly lower in Group B (13.3% v.s. 60.0%, p<0.001). The severity of PPC was also significantly lower in Group B [1(1) v.s. 3(2), p<0.001]. Besides, patients from Group B had significantly less damaged lungs and better postoperative renal function, shorter ICU stay, fewer ICU re-admissions, and lower hospital mortality. High parenteral daily VitC doses (200mg/kg/24h) given to selected CS patients for 48h after CS are safe and effective in reducing the incidence and severity of PPC. Further multicenter RCT is needed to confirm these results.
The Separation of Lithium Ion and Imidazolium Cation by Electrical Driven Membrane Technology
Authors: Jingyi XUE , Xiang MENG , Runci WANG , Yuan Zhongwei , Zheng Weifang
Published: February 2024

The separation of Li+ and [Bmim]+(1-Butyl-3-methylimidazolium) by electrically driven membrane technology was studied. The effects of the types and modification processes of cation exchange membranes, current density, total cation concentration, temperature, and anion types on separation efficiency were investigated. The results indicated that it is feasible to achieve efficient separation of Li+ and [Bmim]+ using the selectivity of cation exchange membranes under electric field. Membrane CMX and the modified membrane A and B which obtained from the CMX showed obvious selective of Li+ from [Bmim]+. When the current density is 5 mA/cm2 and the feed concentrations of Li+ and [Bmim]+ are 0.3 mol/L and 0.2 mol/L, the selective transport coefficient of the modified membrane B can reach 6.2 in the first 120 minutes of the process. Reducing current density and increasing total cation concentration can improve separation efficiency. Lowering the temperature can improve the separation effect, but improvement is not obviously. Changing the anion of the feed from chloride ion to acetate has no effect on the separation.
The Impact of Phenotype of Inflammatory Bowel Diseases, Inflammation Activity and Therapy on Mucosal Mature Cd83+ Dendritic Cell
Authors: Despalatovic Bruna Rosic , Babić Marija , Bratanić Andre , Tonkić Ante , Ardalić Žarko , Vilović Katarina
Published: February 2024

Background: Crohn’s disease (CD) and ulcerative colitis (UC) are well defined phenotypes of chronic inflammatory bowel diseases (IBD). A mechanism of inflammation in these diseases is partially controlled by intestinal dendritic cell (DC). In this study we observed a mature CD83+DC in colonic bioptic samples, and its correlation with disease phenotype and activity.
Methods: There were 219 subjects included in the study: 100 with UC, 44 with CD and 75 healthy subjects. Colonic biopsy specimens were incubated with primary antibody Anti-CD83. Intraepithelial CD83+DC were counted per 100 enterocytes. Presence of CD83+DC was analysed according type of IBD, histopathologic inflammation activity and treatment outcome.
Results: The presence of mature CD83+DCs (0, ≥1) significantly differed among disease types of IBD (p=0.001), histologic inflammation activity (p=0.049) and applied therapy (p=0.001). The odds for CD83+DC presence was 5.2 times higher in CD group than in control/UC group. The odds for CD83+DC presence was 2.6 times higher in subjects without inflammation or chronic inflammation than in acute inflammation. It was also 3.7 times higher in subjects without therapy. The cut-off value 0.5 CD83+DC (Rock analysis area=0.699;
SE 0,046;p<0.001;95%CI:0.609-0.788) had been assessed as a differentiation marker between UC and CD.
Conclusion: Presence of CD83+DC could be used as a possible parameter in distinction between UC and CD, as well as predictor of inflammation activity and treatment outcome.
Optimization of Grid Energy Balance Using V2G Network System
Authors: Deu Carlos Armenta , Demas Laura
Published: February 2024

The paper proposes a methodological way to compensate the imbalance between energy generation and consumption using the battery block of electric vehicles as energy reservoir through the well-known Vehicle to Grid system (V2G). The method is based on a simulation process developed by the authors that take into consideration the daily fluctuations of energy consumption as well as the power level generated by an energy source, either conventional, renewable or hybrid. The study shows that for very large electric vehicle fleet the system renders non-viable, since the remaining energy in the battery block to let the electric vehicle usable for running during daytime avoids to compensating for the energy grid imbalance, only allowing to cover a percentage of the energy imbalance, which the proposed methodology may optimize. The analysis of the proposed methodology also shows the viability of the system when being applied to a small fleet of electric vehicles, not only compensating for the energy imbalance but also preserving the required energy in the battery of the electric vehicle to make it run. The method allows predicting the optimum size of electric vehicle battery, which depends on the energy generation level, coverage factor of the energy imbalance and size of the electric vehicle fleet.
Nonlinear Maccone-Pati Uncertainty Principle
Authors: KRISHNA K. MAHESH
Published: February 2024

We show that one of the two important uncertainty principles derived by Maccone and Pati \textit{[Phys. Rev. Lett., 2014]} can be derived for arbitrary maps defined on subsets of $\mathcal{L}^p$ spaces for $1< p<\infty$. Our main tool is the Clarkson inequalities. We also derive a nonlinear uncertainty principle for weak parallelogram spaces and Type-p Banach spaces.
Main Clinical Characteristics of Medication Overuse Headache
Authors: Ljubisavljevic Srdjan , Todorovic Stefan , Damjanovic Radomir
Published: February 2024

Introduction: Medication overuse headache (MOH) is a secondary headache that occurs 15 or more days per month in patients with preexisting headache. This can result from the excessive (10 or 15 days/month) use of drugs for acute or symptomatic headache therapy.
Aim: To examine the relationships between demographic parameters, illnesses and habits of life, clinical type and length of previous headache and MOH and clinical features of MOH.
Materials and methods: This study was conducted at the Clinic of Neurology, Clinical Center of Niš, and included 83 patients (11 men and 72 women) who were first diagnosed with MOH. The mean age of the patients in the study cohort was 40.5 ± 11.6 years. The study was performed in strict accordance with the Declaration of Helsinki after informed consent was obtained from each participant in the study. The study was approved by the local ethics committee.
Results: In the study cohort, there were more women (86.7%), nonsmokers (59%), those who did not consume alcohol (95.2%), those who were physically inactive (90.4%), those who consumed caffeinated beverages (89.2%), and those with diseases of the cardiovascular (12%) or osseous joint system (10.8%). MOH was most commonly generated by chronic migraine (64%). The duration of MOH until diagnosis was 5.1 ± 5.5 years. The following MOH characteristics were observed: moderate pain (45.8%), bilateral localization (56.6%), temporal presentation (65.1%), and neck tightness (81.9%). Common (41%) and combination analgesics (48.2%) were used most frequently, 15 to 25 days per month. The impact of MOH on daily life was assessed as significant (HIT - 65.4 ± 5.5), correlating with the duration of earlier chronic headaches (r = 0.327, p = 0.003).
Conclusion: MOH can be generated by the transformation of a previous chronic headache due to overuse of analgesic therapy. The MOH significantly affects all aspects of a patient's life. MOH can be prevented by educating patients by limiting the use of analgesic therapy, especially in the at-risk group (middle-aged women with chronic migraines).
Parental Attachment and Psychosocial Adjustment in Adolescents Exposed to Marital Conflict
Authors: Maya Jesús , Fuentes Isabel , Arcos-Romero Ana Isabel , Jiménez Lucía
Published: February 2024

(1) Background: Interparental conflict is a phenomenon that poses a serious threat not only to the quality of life for the couple but also to the father-child relationship, mother-child relationship, and well-being of adolescents. This study examined the influence of marital conflict on father-child and mother-child attachment and the psychosocial adjustment (2) Methods: 67 adolescents involved in Child Welfare Services (CWS) in disadvantaged neighbourhoods in southern Spain were examined. The sample was split into two groups according to the exposure to marital conflict. Subsequently, differences between groups were analysed on father attachment, mother attachment, aggression, antisocial behaviour, and emotional intelligence. (3) Results: Primarily, the data showed significantly worse attachment with the father among conflict-exposed versus non-conflict-exposed adolescents. These results were not found for the attachment with the mother. Additionally, greater anger and worse stress management were found in conflict-exposed adolescents. (4) Conclusions: The results partially confirmed the spillover and compensatory hypothesis. Practical implications point out that developing preventive interventions that protect the father-adolescent attachment in situations of family conflict is recommended.
Using a Metadata Approach to Extend the Functional Resonance Analysis Method to Model Quantitatively, Emergent Behaviours in Complex Systems.
Authors: Hill Rees , Slater David
Published: February 2024

In an increasingly complex world there is a real, urgent need for methodologies to enable engineers to model complex sociotechnical systems, as these now seem to describe the majority of systems in use today. This is of course exacerbated by the increasing involvement and augmentation with “black box” AI contributions. Hollnagel produced a methodology, (FRAM) which did allow the analyst in-sights into these systems’ behaviour, but the model-based system engineering applications demand numbers and a quantitative ap-proach.

In the last 10 years, this original approach developed to model systems as sets of interactive, interdependent “functions”, (abstracted from agent or component details), has been further developed to the point where it can take the basic data and structures from the current component focussed system engineering “models”, and can pull it all together into dynamic models, (as opposed to static, fixed System Theoretic Process Accimaps), from which analysts can discern how they really work in practice, and predict the emergent behaviours characteristic of complex systems.

This paper describes how the FRAM methodology has now been extended to provide these extra, essential attributes. It also describes its implementation using an open-source software, freely available for use and verification on the GitHub site.
Tipología de corpus: hacia una propuesta integradora
Authors: Hernández García Valeria
Published: February 2024

Resumen: La metodología lingüística basada en el trabajo con corpus se implementa en disciplinas tan dispares como la traducción (Baker 1993), el análisis del discurso, la dialectología y la variación, la enseñanza de idiomas y la lingüística, la cultura, la gramática, la estilística lingüística, la lexicografía, la lingüística histórica, la pragmática, la psicolingüística, la psicología social, la semántica, la lingüística textual, y la sociolingüística (McEnery y Wilson 2001: 104-130). Debido al amplio espectro de utilización de la lingüística de corpus, no se ha alcanzado un acuerdo absoluto en cuanto a los tipos de corpus existentes, su denominación y su definición. Por consiguiente, el objetivo del presente artículo es ofrecer una propuesta de clasificación de corpus aplicable a cualquier disciplina. Para tal propósito, de la multitud de categorizaciones encontradas, nos fundamentamos en aquellas formuladas por Sinclair (1996), Torruella Casañas y Llisterri Boix (1999), Laviosa (2002), Fernandes (2006), Borja Albi (2007), Cabré Castellví (2007), Villayandre Llamazares (2008) y Ornia (2015). De manera que delimitamos un total de dieciocho parámetros, y cuarenta y dos tipos de corpus en nuestra propuesta. En definitiva, este trabajo proporciona un instrumento que estandariza el proceso de selección de corpus para llevar a cabo estudios lingüísticos y la enseñanza/el aprendizaje de idiomas.
Palabras clave: Corpus. Tipología. Revisión. Propuesta. Interdisciplinariedad.
La gestión del multilingüismo en contextos migratorios: accesibilidad, traducción e interpretación
Authors: Castillo Bernal Pilar
Published: February 2024

Tras la celebración del 3rd International e-Conference on Translation con el título Movimientos migratorios en Andalucía en su contexto nacional y europeo. La inclusión social a través de la traducción, la interpretación, herramientas y formación digital multilingüe (Universidad de Córdoba, 1-2 de diciembre de 2022), el presente número monográfico tiene por objetivo consolidar y difundir la investigación y proyectos en curso relacionados con los grupos migrantes y la comunicación, especialmente en contextos institucionales. En un entorno global de sociedades cada vez más plurales e interculturales, la facilitación de la información institucional a la población migrante y las minorías lingüísticas es un enfoque predominante en los estudios lingüísticos y traductológicos actuales. Sería virtualmente imposible revisar en un editorial la totalidad de los trabajos de investigación relacionados con estos temas, por lo que nos centraremos en señalar algunas tendencias recientes en investigación en estos contextos.
Hacia una poética de la enfermedad en Las tres mitades de Ino Moxo y otros brujos de la Amazonía de César Calvo
Authors: Di Benedetto Matías
Published: February 2024

Este artículo analiza la obra de Calvo a partir de su intento de narrar la(s) enfermedad(es) por fuera de los tópicos del discurso biomédico. Su objetivo principal es dar cuenta de cómo se subvierten los rasgos principales de la novela de la selva al realizar una reivindicación del accionar y de la retórica de los curanderos amazónicos. De esta forma, nuestro análisis se centra en las prácticas curativas que orbitan alrededor de la ingesta de ayahuasca y en cómo son incorporadas a la ficción de Calvo no solamente como divulgación de los saberes de los vegetalistas, sino también dando por resultado la exposición del meollo de la enfermedad: la desarmonización del sujeto y su ruptura con los lazos que, de lo contrario, lograrían asir su parentesco macroscópico con lo animal y lo vegetal. En conclusión, el registro de lo íntimo que pone en funcionamiento la ficción de Calvo introduce otra forma de abordar el tópico de la enfermedad y, asimismo, transforma el diario de viaje por la selva en un diario de la enfermedad capaz de tensionar las técnicas sagradas de los brujos y el imaginario de lo saludable entendido desde una óptica secular.
Incidencia de la gestión institucional en el bienestar de los estudiantes de la Universidad Nacional de Loja (Ecuador)
Authors: Moreno Alex
Published: February 2024

Como resultado de los profundos efectos de la pandemia en el bienestar de los estudiantes, la gestión de las instituciones educativas juega un papel crucial en la situación actual. Por ello, la investigación tuvo como objetivo determinar la incidencia de la gestión institucional en el bienestar de los estudiantes de la Universidad Nacional de Loja; para el efecto, se realizó un estudio aplicado de enfoque cuantitativo que tomó una muestra de 400 alumnos. Se obtuvo la información con un formulario de preguntas, que fue validado por 5 expertos y que contó con una confiabilidad del 93 %. Los resultados determinaron que el nivel alto de las variables y sus dimensiones alcanzó porcentajes superiores al 60 %; a excepción de la dimensión salud, que logró el 45 %. Se concluye que la variable gestión institucional influye en el bienestar de los estudiantes, y que se debe mejorar de forma integral su salud física y mental.
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La Estimulación multisensorial en sala snoezelen para la integración sensorial de estudiantes con discapacidad en un CEBE de Huánuco (Perú), 2023
Authors: Malpartida Repetto José Luis , Menzala Peralta Celia Consuelo
Published: February 2024

Se define la sala snoezelen como una intervención global que brinda estímulos sensoriales que proporcionan sensaciones agradables de bienestar (Asociación España Snoezelen, 2022). El objetivo de esta investigación fue identificar la influencia de la estimulación multisensorial en la sala snoezelen para la integración sensorial de los alumnos con discapacidad de un Centro de Educación Básica Especial (CEBE) de Huánuco (Perú). Metodológicamente se siguió un paradigma positivista, aplicado, cuantitativo, explicativo, de diseño preexperimental, con preprueba y posprueba con un solo grupo. Las variables fueron la estimulación multisensorial y la integración sensorial aplicadas a una población de 58 estudiantes, con una muestra de 16 a través de un muestreo no probabilístico. El resultado del pretest fue de 87,5 % nivel regular y el postest del 100 %, considerando regular un significado asintótico bilateral de ,001 según la prueba de Wilcoxon. Se concluye que la estimulación multisensorial en la sala snoezelen influye en la integración sensorial de los alumnos con discapacidad en un CEBE de Huánuco (Perú).
Asociación entre el gasto en alimentos y la calidad nutricional en Perú
Authors:   , Bonilla Aguilar Karen Eliana
Published: February 2024

Está demostrado que existe una relación directa entre la calidad nutricional y el gasto alimentario. Sin embargo, el gasto es muy susceptible a los cambios. Por otro lado, existen pocas pruebas sobre la calidad nutricional de los alimentos disponibles en los hogares. El objetivo de este estudio fue evaluar la relación entre la calidad nutricional disponible (CND) y el gasto total en alimentos (GTA) en hogares peruanos, y si existían diferencias por zona (urbana y rural) y entre años de la pandemia COVID-19. Para ello, utilizamos la Encuesta Nacional de Hogares del Perú (ENAHO) de los años 2019 y 2020. Evaluamos el GTA en dólares estadounidenses por día, la CND del hogar basada en la diversidad dietética y el cumplimiento de los requerimientos calóricos del hogar, el porcentaje de gasto en alimentos (PGA) y los posibles factores de confusión. Se utilizó la prueba T de Student, el análisis de la varianza (ANOVA), la regresión lineal y la prueba de Wald para evaluar el efecto de interacción. Se observó que los hogares con una CND adecuada total/parcial por zona gastaban en promedio USD$2 más en las zonas urbanas que en las rurales, y por año tenían un 7,1% más de PGA en 2020 que en 2019. Si bien hubo asociación entre la CND y el GTA por año y área de estudio, la modificación del efecto solo se presentó por área de estudio. En el modelo multivariable, los hogares con CND adecuada total/parcial tuvieron consistentemente un GTA más baja por año, con un GTA más baja en las áreas urbanas. Se encontró una relación inversa entre la CND y el GTA, en contraste con la relación directa de los estudios que evalúan el coste de la dieta y la calidad nutricional. Nuestros resultados reflejan el déficit nutricional en la compra de alimentos de los hogares peruanos.