bluuebunny/crossref_metadata_2025 huggingface dataset:
A Research on Hybrid Cloud Computing
Authors: Mahaswarup B , J Bhuvana
Published: May 2024

Dual distributed computing has arisen as a significant answer for present day ventures trying to use the benefits of both public and confidential cloud foundations. This theoretical digs into the pith of crossover distributed computing, inspecting its design, advantages, challenges, and arising patterns molding its reception. Cross breed cloud engineering consistently incorporates public and confidential cloud conditions, permitting associations to improve responsibility position in view of elements like security, consistence, execution, and cost-proficiency. By mixing the versatility and adaptability of public mists with the control and customization of private mists, dual models engage endeavors to draftsman modern IT environments custom-made to their extraordinary necessities. The advantages of mixed distributed computing are complex. Associations can powerfully scale assets, moving responsibilities between conditions to successfully oblige vacillations sought after. Furthermore, mixture mists work with information sway, empowering endeavors to hold delicate information on-premises while utilizing the dexterity of public mists for less basic responsibilities. This flexibility encourages development and speeds up computerized change drives, enabling organizations to remain deft and serious in a quickly developing scene. In any case, hybrid cloud reception likewise presents difficulties. Overseeing different cloud conditions presents intricacy, requiring powerful administration structures, robotization devices, and gifted faculty to guarantee consistent organization and security across the mixture framework. Interoperability issues, information coordination concerns, and potential seller secure in additional highlight the significance of fastidious preparation and vital dynamic in crossover cloud arrangements. Looking forward, a few patterns are reshaping the hybrid cloud scene. Edge registering is acquiring conspicuousness, driving the decentralization of information handling and stockpiling to the organization edge, subsequently enlarging mixed models with edge capacities. Besides, progressions in containerization advances, like Kubernetes, are working with compactness and responsibility portability across mixed conditions, upgrading spryness and asset use. All in all, dual distributed computing addresses a change in outlook in IT framework the executives, offering a strong mix of adaptability, versatility, and control. While reception involves difficulties, the essential reconciliation of public and confidential mists can open unmatched open doors for advancement and effectiveness in the computerized time. Embracing mixed cloud structures enables undertakings to explore intricacy, mitigate risk, and benefit from arising advancements to drive feasible development and upper hand.
5G Wireless Networks
Authors: M Kishor , . Bhuvana
Published: May 2024

5G stands for fifth-generation remote innovation. It is the most recent cycle of cellular innovation that has three primary highlights: more noteworthy speed, lower idleness, and the capacity to interface a parcel more gadgets at the same time. A commercial 5G remote arrange is anticipated to be conveyed by 2020. This paper gives a brief presentation to 5G remote technology. Keywords: 5G remote innovation, advancement from 1G to 5G
Comprehensive Review on Leveraging AI and Machine Learning in Digital Banking
Authors: Kumar Swaraj , R Kavitha
Published: May 2024

In recent years, the integration of machine learning (ML) and artificial intelligence (AI) technologies has revolutionized the landscape of digital banking. This review paper synthesizes the current state of research and practical implementations regarding the utilization of ML and AI in digital banking services. Leveraging a comprehensive review of scholarly articles, industry reports, and case studies, this paper examines key applications of ML and AI in enhancing various facets of digital banking, including fraud detection, customer service, risk assessment, personalization, and predictive analytics. Additionally, it explores the challenges and opportunities associated with the adoption of ML and AI in the banking sector, such as data privacy concerns, regulatory compliance, algorithmic biases, and the evolving role of human interaction. By critically analysing existing literature and real-world examples, this paper aims to provide insights into the transformative potential of ML and AI technologies in reshaping the future of digital banking, while also highlighting areas for further research and development.
Cloud Quanta: Pioneering the Future of Quantum Computing in the Cloud
Authors: Kokate Loukik , . Srikanth
Published: May 2024

Quantum computing has emerged as a revolutionary approach to solving complex problems that demand powerful computational capabilities. With various cloud quantum computing services available, users are presented with different architectures and performances. In this study, we conduct research on select cloud quantum computing services to evaluate their performances and compare them. Using two different methods, visual programming and Qiskit, we test these services and analyze the impact of factors such as the number of qubits per backend and shots per run on execution time. Our findings provide users with insights to decide which cloud quantum computing services offer better performance or faster execution times based on their specific requirements.
Financial Implications of Fast Fashion in India: A Comprehensive Study on Profitability, Sustainability, and Consumer Behavior
Authors: Mishra Muskan , Prakash Yerragola
Published: May 2024

The emergence of fast fashion has significantly impacted the Indian clothing industry. This research investigates the financial dimensions of fast fashion in India, focusing on profitability, sustainability, and consumer behavior. The study analyzes how fast fashion affects the profitability of clothing companies in India. It also examines the sustainability practices adopted within the fast fashion sector and their implications for both businesses and the environment. Moreover, the research explores the influence of consumer behavior on the financial performance of fast fashion brands in India, considering variables such as price sensitivity, brand loyalty, and the growing demand for sustainable options. By providing insights into these areas, this study aims to offer valuable perspectives on the financial dynamics of fast fashion in India, aiding stakeholders in making informed decisions to balance profitability with sustainability in the industry.
Financial Strategies of Attracting and Retaining Talent at Tata Motors
Authors: Prerana Rajpurohit , Choudhary Anita
Published: May 2024

For businesses like Tata Motors, talent has become the most precious asset in today's intensely competitive automotive sector. This abstract explores the financial tactics used by Tata Motors to draw in and hold on to elite personnel, which in turn ensures long-term success and growth for the company. Tata Motors understands how important it is to provide competitive pay packages in order to draw in the top personnel available. The company maintains its wage structures in line with industry norms by carefully examining the market and benchmarking. Tata Motors also uses performance-linked incentives, which match organizational and individual objectives to reward excellence and produce outcomes. Tata Motors aims to establish a financially satisfying work environment that inspires employees to achieve by combining competitive compensation with performance bonuses. Apart from monetary compensation, Tata Motors prioritizes offering extensive benefits to its employees. These benefits include retirement plans, health insurance, and a host of additional advantages aimed at improving the general happiness and well-being of its employees. Tata Motors promotes a culture of dedication and loyalty among its workers by putting employee wellbeing first, which increases retention rates. In addition, Tata Motors makes large investments in learning and development programs to cultivate talent and promote career advancement. Through educational opportunities, skill-building workshops, and training programs, the organization provides its employees with the tools and information they need to succeed in their positions. Tata Motors fosters a culture of innovation and adaptation in addition to improving individual performance by enabling staff members to pursue ongoing professional development.
Śródziemnomorski Shakespeare. Libretto Arriga Boita do Falstaffa Giuseppe Verdiego
Authors:   Narodowy Instytut Fryderyka Chopina w Warszawie, Stępień-Kutera Kamila
Published: May 2024

The article presents the circumstances of the creation of Falstaff by Giuseppe Verdi, his last opera, one of the two to a libretto by Arrigo Boito. The author reveals behind the scene of working on that masterpiece referring to source materials that include, among other documents, fragments of letters by Verdi, Boito and Giulio Ricordi, translated by the author and published for the first time in Polish. The key features of Boito’s libretto – sources he used, his attitude to Shakespeare’s originals, versification and poetic means are also discussed (the article provides us with the fragments of the libretto both in the original language – Italian and, similarly to the letters, in the author’s translation). The article is an adapted version of fragments of the author’s doctoral thesis Arrigo Boito and his concepts of the opera, supervised by professor Michał Bristiger and defended at the Institute of Art of the Polish Academy of Sciences in 2014.
Perspektywy muzycznej sztucznej inteligencji
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Krzyżanowski Wojciech
Published: May 2024

Recently we have been witnessing an amazing outburst of visual art done by Artificial Intelligence based on texts prompts. Will it ever be able to exhibit such a creative approach towards music? Before we answer, we should learn some basics of these systems. Artificial Intelligence powered by machine learning becomes more effective through exposure to empirical data. By analysing similarities and differences between hundreds of thousands of photographs of violin, it understands what a violin can look like, without being given any other explicit instruction. Machine learning systems specialize in recognizing objects and GAN networks can also generate new objects based on the analysed data. As for now there is no highly effective and diverse system to produce music based only on informal text prompts. But its existence is theoretically possible. We can even envision more complex systems, which automate such output around biological user feedback.
Case Series on Imaging Features of Trilateral and Quadrilateral Retinoblastoma: What Radiologists Need to Know
Authors: Fiona Fiona , Yuli Anandasari Pande Putu , Margiani Ni Nyoman
Published: May 2024

Objective: To identify the differences between trilateral and quadrilateral retinoblastoma based on radiologic imaging.Case: We found three cases of retinoblastoma at Sanglah General Hospital. The retinoblastoma patients we found were boys under the age of 5. The first patient presented with swelling, pain, and impaired vision in the right eye. The second and third patients presented with eye protrusion and leukocoria. Computed tomography (CT) imaging revealed a calcified mass in the intraorbital region that extended to the cerebral hemispheres. It may be accompanied by hair-on-end periosteal reaction. In the first patient, the mass extended to the pineal gland. In the second and third patients, the mass extended to the suprasellar and pineal regions.  Trilateral retinoblastoma consists of a primordial midline neuroectodermal tumor that originates in the pineal or suprasellar region. It is an uncommon combination of unilateral or bilateral retinoblastomas. Quadrilateral retinoblastoma, on the other hand, presents with bilateral retinoblastoma and tumors in both the suprasellar and pineal regions. The histopathology of trilateral and quadrilateral retinoblastoma shows a different pattern from retinoblastoma.Conclusion: Retinoblastoma poses one of the most challenging problems due to its distinct patterns of growth, extension, and recurrence. Intracranial metastasis of trilateral and quadrilateral retinoblastoma exhibits a different pattern. The prognosis and diagnosis of retinoblastoma are significantly influenced by clinical examination, radiologic imaging, and histopathology.
Subclinical Left Ventricular Dysfunction Prevention in Breast Cancer Patients after FAC Chemotherapy: A Carvedilol Trial
Authors: Astuti Astri , Sumantra I Gede , Aafiyah Adila , Abdurahman R. Maman , Sihite Teddy Arnold , Akbar Mohammad Rizki , Hasan Melawati , Martanto Erwan
Published: May 2024

Objective:  To assess the cardioprotective effects of Carvedilol in preventing subclinical left ventricular dysfunction (SLVD) in breast cancer patients after completing FAC chemotherapy.Methods: This prospective study employed a quasi-experimental clinical trial conducted from September 2018 to May 2019. Breast cancer patients receiving FAC chemotherapy were divided into two groups: intervention (IG) and control (CG). The IG received Carvedilol 6.25 mg b.i.d., which was increased every three weeks until reaching a tolerated dose. The study evaluated changes in left ventricular global longitudinal strain (GLS) and the incidence of SLVD (GLS reduction ≥15% and GLS >-18%) 24 weeks after initiating the FAC regimen.Result: Of the 81 women enrolled in the study, 31 were in the IG. No significant changes in GLS were observed during or after completing FAC chemotherapy in the IG, whereas the CG showed contradictory results. At the end of the follow-up period, the delta GLS reduction was lower in the IG (0.7; 95% CI -0.60, 3.60) compared to the CG (3.00; 95% CI -2.16, 4.19), with a p-value of 0.035. Similarly, the percentage reduction in GLS was 3.6% in the IG and 14.29% in the CG, resulting in a p-value of 0.05. The incidence rate of SLVD (GLS reduction ≥15% and GLS > -18%) was lower in the IG (41.9% and 25.8%) than in the CG (58% and 48%).Conclusion: Carvedilol may have a cardioprotective effect in preventing the incidence of SLVD, as evaluated by GLS reduction and changes, in women with breast cancer after completing a full cycle of the FAC regimen.
Transferência de tecnologia para vacina contra COVID-19 no Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), Fundação Oswaldo Cruz
Authors: Rosenberg Vivianne Zalmon , Antunes Adelaide Maria de Souza
Published: May 2024

Resumo: A inovação é um elemento fundamental para o desenvolvimento e crescimento, mas constituída por um processo demorado de acúmulo de conhecimento. Uma das formas de acelerar tal processo é por meio da transferência de tecnologia. Este artigo mapeou as particularidades da transferência de tecnologia para a vacina contra COVID-19, celebrado entre a AstraZeneca e o Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), Fundação Oswaldo Cruz, bem como reconheceu os seus facilitadores, seus entraves e suas lacunas. Para tanto, foi realizada uma análise desde a etapa da seleção do parceiro mais adequado até a incorporação da nova tecnologia. A metodologia utilizada se baseou em uma ampla revisão bibliográfica sobre o tema, aliada ao estudo de caso. Os resultados apontaram que, apesar de muitas ações ainda precisarem ser realizadas para que os ganhos de capacidade tecnológica sejam potencializados, as lições aprendidas com o processo de transferência de tecnologia servirão de aprendizado e serão utilizadas nos acordos futuros e em andamento.
Descobrindo os sujeitos do mercado: “Quem somos nós quando trabalhamos?”
Authors: Herzog Lisa M. , Souza Luiz Gustavo da Cunha de , Simim Thiago Aguiar
Published: May 2024

Resumo O artigo de Lisa Herzog examina como Adam Smith e G. W. F. Hegel conceitualizam a identidade de trabalhadores no mercado. Embora ambos vejam seres humanos como indivíduos formados dentro de relações sociais e por meio delas, a relação entre o trabalhador e seu trabalho é vista por eles de modos diferentes. Para Smith, trabalhadores “possuem” capital humano, enquanto, para Hegel, trabalhadores “são” cervejeiros, açougueiros ou padeiros, pois sua profissão é parte de sua identidade. Essa diferença conceitual, que se reflete em diferentes “variedades de capitalismo” contemporâneas, mostra que não apenas graus, mas também tipos de enraizamento devem ser distinguidos na discussão sobre a relação entre indivíduo e sociedade. O artigo é precedido de uma apresentação feita pelos tradutores.
Por uma sociologia política do trabalho: “Democracia e divisão do trabalho social” de Axel Honneth
Authors: Honneth Axel , Sobottka Emil Albert , Souza Luiz Gustavo da Cunha de , Simim Thiago Aguiar
Published: May 2024

Resumo Neste artigo apresentamos nossa tradução e introdução crítica ao texto “Democracia e divisão do trabalho social: mais um capítulo negligenciado da filosofia política” em que Axel Honneth apresenta a tese de que a divisão do trabalho social possui íntima relação com a distribuição de chances de participação política e, afinal, com a qualidade da democracia em sociedades modernas. Partindo da constatação de que a teoria política contemporânea raramente se dedicou ao estudo de questões relacionadas ao mundo trabalho dos sujeitos políticos, o autor propõe uma atualização sistemática da concepção de divisão do trabalho social, por meio da qual não apenas as atividades laborais sejam vistas como passíveis de reformulação, mas também a concepção mesma daquilo que é tradicionalmente considerado como trabalho social.
Teoria crítica e sociologia do trabalho e do mercado
Authors: Souza Luiz Gustavo da Cunha de , Simim Thiago Aguiar
Published: May 2024

Resumo Em sua história centenária, a tradição de pensamento conhecida como teoria crítica da sociedade, inicialmente associada à Escola de Frankfurt e posteriormente desenvolvida como uma ampla perspectiva teórica, atribuiu lugar central ao trabalho, seja por meio da reflexão conceitual sobre essa categoria seja por meio de análises histórico-diagnósticas das transformações nas atividades concretas de trabalho. Assim, às vezes de modo mais estreito, outras de modo mais tenso, a teoria crítica buscou conectar a dimensão normativa da atividade genérica do trabalho com a investigação sobre dimensões intersubjetivas e morais das relações que envolvem o mercado de trabalho. No presente texto, apresentamos introdutoriamente a trajetória do conceito de trabalho e da análise do mercado capitalista na teoria crítica, tomando por base os textos que compõem o dossiê “Teoria crítica e sociologia do trabalho e do mercado”, apresentado na sequência. Além de comentar brevemente os textos do dossiê, indicamos sua conexão com a tentativa mais recente de retomar o tema no âmbito da teoria crítica, a monografia de Axel Honneth, lançada em 2023, chamada O trabalhador soberano. Uma teoria normativa do trabalho.
Análise de sobrevida de portadores da doença de Chagas, beneficiários da previdência e da assistência social no Brasil, 1942–2016
Authors: Limongi Jean Ezequiel , Santos Keile Aparecida Resende , Perissato Izabela Lima , Pinto Rogério de Melo Costa , Mendonça Tânia Maria da Silva , Rinaldi Ana Elisa Madalena
Published: May 2024

RESUMO Objetivo Analisar a sobrevida de portadores da doença de Chagas, beneficiários da previdência e da assistência social no Brasil, 1942-2016. Métodos Estudo de coorte retrospectivo com dados do Ministério da Previdência Social. O evento de interesse foi o óbito, e as funções de sobrevida foram estimadas pelos métodos Kaplan-Meier e de regressão de Cox. Resultados No período “início da doença até o óbito”, o sexo feminino (HR=0,54; IC95% 0,43–0,53) e recebimento de benefícios previdenciários (HR=0,13; IC95% 0,11–0,23) foram associados a maior sobrevida. A menor sobrevida esteve associada à forma cardíaca da doença (HR=2,64; IC95% 2,23–3,12), residência em zona rural (HR=1,23; IC95% 1,14–1,21) e manifestação da doença entre os anos de 2000 e 2016 (HR=5,32; IC95% 4,74–5,93). Da mesma forma, no período “incapacidade laboral até o óbito”, o sexo feminino (HR=0,51; IC95% 0,41–0,52) e o recebimento de benefícios previdenciários (HR=0,24; IC95% 0,14–0,45) foram associados a maior sobrevida, assim como forma cardíaca da doença (HR=1,95; IC95% 1,83–2,13), residência em zona rural (HR=1,31; IC95% 1,21–1,54) e manifestação da doença entre os anos de 2000 e 2016 (HR=1,53; IC95% 1,33–1,71) associaram-se a menor sobrevida. Conclusão Os principais preditores de mortalidade e sobrevida de portadores de doença de Chagas que recebem benefícios previdenciários e assistenciais no Brasil foram apresentados. Estes achados podem nortear a definição de prioridades de ações de acompanhamento pela atenção primária à saúde, preconizada atualmente para o manejo longitudinal da doença.
Desigualdades Educacionais no Brasil Contemporâneo: Definição, Medida e Resultados
Authors: Ernica Mauricio , Rodrigues Erica Castilho , Soares José Francisco
Published: May 2024

Resumo Este artigo propõe um indicador que descreve, para cada município brasileiro, o nível de aprendizagem de seus estudantes do ensino fundamental e as desigualdades de aprendizagem entre grupos de estudantes definidos por nível socioeconômico, raça e sexo. Esse indicador é necessário porque as desigualdades de aprendizagem são crescentes e, contudo, não são observadas pelo principal indicador educacional do país, o Índice de Desenvolvimento da Educação Básica (IDEB). O estudo inicialmente conceitualiza justiça em educação, situando-se no debate sobre teorias de justiça distributiva. Em seguida, apresenta os aspectos metodológicos do indicador e os resultados obtidos. A principal constatação é que as disciplinas e séries escolares nas quais se verificou o maior número de municípios aumentando o seu nível de aprendizagem são também aquelas em que se verificou forte aumento das desigualdades.
Education Inequalities in Contemporary Brazil: Definition, Measurement, and Outcomes
Authors: Ernica Mauricio , Rodrigues Erica Castilho , Soares José Francisco
Published: May 2024

Abstract This article proposes an indicator that describes each Brazilian municipality’s learning level of its elementary school students, as well as learning inequalities among groups of students defined by socioeconomic status, race, and sex. This indicator is necessary because learning inequalities are growing and are not observed by the country’s main educational indicator, the Basic Education Development Index (IDEB). This study initially conceptualizes justice in education, positioning itself in the debate on theories of justice. Then, it presents the methodological aspects of the indicator and the results obtained. The main finding is that the subjects and school grades in which the highest number of municipalities increased their learning levels are also those in which there was a strong increase in inequalities.
A Gramática Institucional da Proteção de Dados e da Privacidade no Brasil
Authors: Filgueiras Fernando , Lui Lizandro , Veloso Maria Tereza Trindade
Published: May 2024

Resumo Este artigo investiga a gramática institucional da proteção de dados e da privacidade no Brasil. Adotando a lente analítica do Intitutional Grammar Tool (IGT), desconstruímos os enunciados institucionais dos decretos regulamentadores da Lei Geral de Proteção de Dados dos estados brasileiros, de forma a classificar os diferentes elementos gramaticais que informam as estratégias estaduais de proteção e governança de dados. Examinamos nesse artigo a construção dos conceitos de proteção de dados, governança de dados e privacidade, assim como a construção institucional da proteção de dados no Brasil. O estudo tem um viés empírico, de maneira a responder às seguintes questões: qual o desenho institucional das estratégias adotadas pelos estados, no contexto da federação, para a proteção de dados pessoais e da privacidade dos cidadãos? Quais as implicações desse desenho para a efetividade da proteção de dados no Brasil? O artigo conclui que as estratégias de proteção de dados formuladas nos estados têm mais o viés de controle burocrático do tratamento de dados do que propriamente a efetivação de direitos emergentes de cidadania.
Antonio Gramsci em Refração: os Usos de Fernando Henrique Cardoso
Authors: Mussi Daniela , Herscovici Nicole
Published: May 2024

Resumo O artigo tem como objetivo investigar um percurso singular de recepção e tradução das ideias de Antonio Gramsci no Brasil. Este trabalho visa reconstruir o pensamento político de Fernando Henrique Cardoso durante a ditadura militar e a transição democrática brasileira (1964-1988) tomando como fio condutor a interpretação e uso que esse autor faz das ideias de Antonio Gramsci ao longo do tempo para a análise da formação do Estado, das classes sociais e da política no Brasil. O texto desenvolve a hipótese da centralidade dos conceitos gramscianos no pensamento de Cardoso em três fases de refração gramsciana: i) entre 1964 e 1974, na tese da hegemonia dependente da burguesia no Brasil, ii) entre 1974 e 1983, na defesa do Estado brasileiro como “Príncipe Moderno” enquanto categoria para análise da coalizão agrário-industrial-militar no pós-1964, e iii) de 1983 a 1988, na formulação do transformismo autoritário-esclarecido como comportamento das elites econômicas e militares brasileiras diante da pressão pela democratização do regime. Os usos dos conceitos gramscianos em Cardoso são criativos em todos esses momentos. Isto é, o pensador brasileiro se inspira nos conceitos gramscianos para criar seu próprio léxico a ser utilizado na análise da política brasileira. O artigo explora, portanto, não apenas a recepção, mas também a tradução das ideias de Gramsci em Fernando Henrique Cardoso.
Saúde mental no Brasil em tempos de pandemia e neoliberalismo: retrocessos e resistências
Authors: Oliveira Cláudia Freitas de
Published: May 2024

Resumo O trabalho analisa aspectos da saúde mental no Brasil como campo político ativo, que envolve vários atores e segmentos sociais em áreas de disputa opostas, em tempos de pandemia e de avanço do projeto neoliberal. Tem como início de delimitação temporal 2016, quando as políticas de austeridade fiscal entram na agenda nacional, e vai até os dias atuais com o cenário da pandemia, ambas ainda vigentes, embora a pandemia tenha diminuído sua intensidade. No âmbito da saúde mental, a política nacional enfrenta profundos retrocessos quanto aos princípios da reforma psiquiátrica. Entretanto, a despeito da tentativa do Estado de desestimular o controle social e a participação popular, observam-se resistências de importantes setores.
A criação da Fundação Brasileira para a Conservação da Natureza
Authors: Souza Juliana da Costa Gomes de , Franco José Luiz de Andrade , Drummond José Augusto
Published: May 2024

Resumo Este estudo se insere no campo da história ambiental e tem o objetivo de compreender o cenário de criação, entre 1958 e 1966, da Fundação Brasileira para a Conservação da Natureza, importante organização não governamental ambientalista brasileira, com sede no Rio de Janeiro e atuação local, nacional e internacional. Para isso, utiliza fontes documentais primárias e pesquisa bibliográfica relacionada. As conclusões demonstraram a importância da existência de organizações não governamentais mais antigas que a fundação e a influência de conservacionistas sobre sua criação e sua atuação inicial.
Predictive abilities of constitutive models for clay under monotonic and cyclic loading: element tests and centrifuge experiments
Authors: Tafili Merita , Staubach Patrick , Machaček Jan , Zachert Hauke , Wichtmann Torsten
Published: May 2024

A critical investigation of three constitutive models for clay by means of analyses of a sophisticated laboratory testing programme and of centrifuge tests on monopiles in clay subjected to (cyclic) lateral loading is presented. Constitutive models of varying complexity – namely, the basic modified Cam Clay model, the hypoplastic model with intergranular strain (known as the clay hypoplasticity model) and the more recently proposed anisotropic visco-intergranular strain anisotropy (AVISA) model – are considered. From the simulations of the centrifuge tests with monotonic loading it is concluded that all three constitutive models give satisfactory results if a proper calibration of constitutive model parameters and proper initialisation of state variables is ensured. In the case of cyclic loading, the AVISA model is found to offer superior performance over the hypoplastic model with intergranular strain.
Graphite nanosheets exfoliated by supercritical carbon dioxide for aluminium-ion battery
Authors: Wang Li , Qiu Jiacheng , Feng Jianmin , Dong Lei , Long Conglai , Li Dejun , Wang Xiaowei
Published: May 2024

Aluminium-ion batteries (AIBs), using commercial graphite as cathodes, stand out as promising secondary energy-storage devices for industrial application. While exfoliating graphite to graphite nanosheets holds substantial theoretical potential for significantly enhancing AIB performance, traditional redox strategies have the drawback of introducing defects and functional groups. In this work, graphite nanosheets exfoliated by supercritical carbon dioxide (GNS-20) were explored for high-performance AIB cathodes. Electrochemical tests showed that the specific capacity of GNS-20 for an AIB cathode was 152 mAh/g at a current density of 4 A/g during 1000 cycles, which was 1.9 times higher than that of natural graphite and 1.47 times higher than that of defect-rich reduced graphene oxide. Further, the regulation of the interlayer pore structure of GNS-20 proved instrumental in enhancing its AIB performance. Modulating the porosity of graphite nanosheets by adjusting the exfoliation pressure had a significant impact. The porosity of graphite nanosheets at an exfoliation pressure of 20 MPa was 86.7%, while the porosity at 15 MPa was 71.5% and that at 10 MPa was 69.7%, the latter two corresponding to capacities of 117 and 99 mAh/g (4 A/g), respectively. This approach simplifies the process and aligns with environmental principles, offering significant potential for various graphite nanosheet applications.
Nesting crawls and associated behaviors of turtles in the genus Batagur along the Chambal River, India
Authors: Pareek Pawan Shantiprakash , Singh Shailendra , Dutta Sreeparna
Published: May 2024

The pattern of nesting crawls and related behaviors can play a very important role in the survival of the eggs aswell as the emerging hatchlings. Studies on marine turtles suggest that nest location can increase exposure to predation,cause thermal stress and dehydration, and consume valuable stored energy in emerged hatchlings, all of which decreasethe likelihood of survival. Red-crowned Roofed Turtles (Batagur kachuga) and Three-striped Roofed Turtles (Batagurdhongoka) are listed as critically endangered on the IUCN Red List. We surveyed a 30-km stretch of sandbank along theChambal River during Batagur nesting seasons in February to early April 2017–2019 and encountered a total of 640nests along eight sand banks. Nesting crawls of B. dhongoka from the water’s edge to successful nesting sites were significantlylonger than those of B. kachuga. We observed only one type of nesting crawl pattern for B. kachuga, whereas fourtypes of such crawls were recorded for B. dhongoka. Moreover, nest shapes differed significantly between the two species.
Efficacy and safety of bevacizumab in neoadjuvant and concurrent chemoradiotherapy for refractory cervical cancer patients
Authors: Yang Hua , Huang Shi Gao , Dong Mohan , Wang Xiaomeng , He JunHua , Su Huyan , Liu Changhao , Zhu Yong , Wei Lichun , Liu Zi
Published: May 2024

A platinum-based concurrent chemoradiotherapy (CCRT) is the standard treatment for refractory cervical cancer (CC). However, the recurrence of disease and the occurrence of metastasis remain prevalent. We observed the long-term efficacy and safety of bevacizumab combined with neoadjuvant chemotherapy (NACT) and CCRT in refractory CC. A total of 62 patients with refractory CC were enrolled in this study from January 2016 to December 2019. The NACT regimen included bevacizumab (7.5 mg/kg), docetaxel (75 mg/m2), and cisplatin (75 mg/m2), administered tri-weekly for 2 cycles. The CCRT regimen included bevacizumab (7.5 mg/kg) and cisplatin (75 mg/m2), administered tri-weekly for 2 cycles. A dose of 45-50 Gy was prescribed for external beam radiotherapy (EBRT), while 30-35 Gy in 4-5 fractions was prescribed for brachytherapy (BT). Among the patients, 21 patients (33.9%) were at stages IIB-IIIB, 8 patients (12.9%) were at stage IIIC1, 19 patients (30.6%) were at stage IIIC2, and 14 patients (22.6%) were at stage IVB. Pelvic, para-aortic, supraclavicular, and inguinal lymph node metastases were discovered in 41 patients (66.1%). The median follow-up was 49.8 months (12.3-82.7 months). The median tumor volumes pre-treatment, after NACT, and before BT were 84.64 ± 53.15 cm3, 1.64 ± 13.15 cm3, and 0 ± 1.5 cm3, respectively. Complete clinical response (cCR) rates after NACT and EBRT were 35.5% and 66.1%, respectively. Four years after the diagnosis, the overall survival (OS) rate was 78.6%, the local region-free survival (LRFS) rate was 91.3%, the disease-free survival (DFS) rate was 70.6%, and the distant metastasis-free survival (DMFS) rate was 81.4%. A total of 29 patients (46.8%) experienced grade 3/4 hematological toxicity, 3 patients (4.8%) experienced grade 3 gastrointestinal toxicities, and none experienced grade 5 adverse events. Bevacizumab combined with NACT and CCRT significantly improved cCR and OS in refractory CC with acceptable toxicity.
Parçacık sürü optimizasyonu temelli ultra hızlı yenilenebilir enerji kaynağı optimizasyon aracı tasarımı
Authors: Altın Cemil
Published: May 2024

Bu çalışmada, Hibrit Yenilenebilr Enerji Siatemleri optimizasyonunda kullanılmak üzere bu alanda en sık kullanılan HOMER programının olumsuz yönlerini bertaraf eden metasezgisel Parçacık Sürü Optimizasyonu tabanlı optimizasyon aracı tasarımı yapılmıştır. Güvenilirliğinin ortaya konması nedeniyle aynı yükü beslemek için gerekli hibrit sistem, hem geliştirilen araç ile hemde HOMER optimizasyon yazılımı ile optimize edilerek sonuçlar karşılaştırılmıştır. İşlem hızı bakımından yapılan karşılaştırmada aynı sistemi optimize etmede, HOMER yazılımının 936 saniyede elde etmiş olduğu sonucu 17 saniyede elde ederek tasarlanan sistemin daha hızlı sonuca ulaştığı görülmüştür. Ekonomik yönden yapılan karşılaştırmada ise iki ayrı aracın yapmış olduğu optimizasyon sonucunda; Enerji maliyetinde 1.737 % , Toplam Net Bugün ki Maliyette 0.85 % ve Başlangıç Sermayesinde ise 1.895 % lik fark bulunmakta olup sonuçlar arasında önemli bir farkın bulunmadığı gözlenmiştir. Elektriksel sonuçların kıyasında ise Beslenen yüklerde 0.031 %, Beslenemeyen yüklerde 1.071 % lik fark çıkmış olup elektriksel anlamda da sonuçların güvenilirliği ortaya konmuştur. Sonuçlar bu alandaki detaylı optimizasyon çalışmaları için umut vericidir. Ayrıca HOMER yazılımının sunmakta olduğu, ekonomik ve elektriksel detaylar, gerçeği temsil eden özgün bir sevk stratejisi sayesinde tasarlanan araç ile de kullanıcıya sunulmaktadır. Güvenilirlik parametresi olarak HOMER yazılımının içerdiği fakat daha önce metasezgisel algoritmalarla yapılan optimizasyon süreçlerinde hiç kullanılmamış olan kapasite eksikliği parametresi kullanılmaktadır. Kapasite eksikliği parametresi ilk defa metasezgisel algoritma ile yenilenebilir enerji kaynaklarının optimizasyonunda kullanılmıştır. Maliyet fonksiyonu olarak Enerji Maliyeti kullanılmıştır. Kısacası HOMER programına alternatif çok daha hızlı sonuca ulaşabilen ve HOMER programındaki hassasiyet, hantallık ve zorlu arama uzayı oluşturma süreçlerini bertaraf eden özgün, güvenilir bir optimizasyon aracı tasarlanmıştır. Bu araç sayesinde ayrıca, vekil modelleri, makine öğrenmesi veya derin öğrenme tabanlı optimizasyon sistemlerini eğitmek için gerekli optimizasyon çıktıları çok hızlı bir şekilde elde edilerek fazla sayıda veri üretilmesi kolaylaşacaktır.
Silver nanoparticles forensic uses and toxicity on vital organs and different body systems
Authors: Mashael Kh ALAtawi , Asma A AlAsmari , Abeer Dh AlAliany , Maryim M Almajed , Mohamed Ibrahim Sakran
Published: May 2024

This study aimed to investigate the forensic uses and potential toxicity of silver nanoparticles on vital organs and different body systems. A systematic review methodology was used to identify and critically evaluate the literature on the forensic uses of silver nanoparticles in different fields and to assess their potential toxicity on various vital organs and body systems. The study found that silver nanoparticles have potential forensic uses, particularly in forensic biology and forensic toxicology, but there are concerns about their potential toxicity. The study recommends further research on the mechanisms of toxicity of silver nanoparticles and the development of safe and effective strategies for their use in forensic science. The study’s strengths include its systematic review methodology and use of multiple databases, while limitations include a limited time frame and focus on English language publications. Future research should focus on investigating the potential risks of silver nanoparticle exposure for forensic professionals.
Synthesis and Biological Evaluation of 3-(2-Benzoyl-4-chlorophenyl)-4H-spiro [indole-3,2-[1,3]thiazolidine]-2,4(1H)- dione Derivatives for Anti-tubercular and Antimicrobial Activities
Authors:   Department of Pharmaceutical Chemistry, Krupanidhi College of Pharmacy, Carmelaram post, Bangalore, 560035, Karnataka, India, Rani U Usha , Sreedevi A
Published: May 2024

Objectives: To synthesize a new scaff fold of 3'-(2-Benzoyl-4-chlorophenyl)-4'H-spiro [indole-3,2'-[1,3] thiazolidine]-2,4'(1H)-dione derivatives and to assess the compounds for anti-tubercular and antimicrobial activities. Methods : A new series of 3'-(2-Benzoyl-4-chlorophenyl)-4'H-spiro [indole-3,2'- [1,3] thiazolidine]-2,4'(1H)-dione derivatives were prepared by synthesizing schiff’s bases followed by condensing schiff base with 2-mercaptopropanoic acid in the presence of zinc chloride. Synthesized compounds were characterized by IR, NMR and Mass spectral data. Their antimicrobial, antitubercular and also docking simulations were evaluated. Findings : Compound 3c (floro substituent) showed potent activity against Mycobacterium tuberculosis H37Rv with MIC value of 3.125 µg/ml when compared with standard Isoniazid. Compound 3c, 3d and 3f displayed better antimicrobial activity against used bacterial and fungal species with MIC range of 3-20µg/ml comparable to standard drugs ciprofloxacin and ketoconazole respectively. In silico studies revealed that compound 3c, 3f and 3d had a better binding affinity with M. tuberculosis enoyl-CoA hydratase EchA6 with ΔG values of -9.6kcal/mol, -9.4kcal/mol, and -8.6kcal/mol respectively comparable to isoniazid of -5.4kcal/mol. Compound 3c, 3f and 3d also displayed good binding affinity with DNA gyrase and lanosterol methylase. Novelty : Introducing benzoyl moiety to the thiazolidine ring potentiates the antitubercular and antimicrobial activity of spiro indole derivatives. Keywords: AntiTB, Antimicrobial, Molecular Docking, Spiro indole, Thiazolidine
Phenocycler-Fusion Staining Protocol For Bone Marrow Tissue v2
Authors: J Ahn Kyung , Bandyopadhyay Shovik , Thadi Anusha , Tan Kai
Published: May 2024

This protocol describes the method for antibody staining of FFPE bone marrow tissue on slides using CODEX barcoded antibodies. The Akoya Phenocycler-Fusion user manual was modified to include photobleaching steps. Included are the stepwise protocols for tissue procurement, tissue decalcification, tissue sectioning, pre-staining, deparaffinization, antigen retrieval, photobleaching, antibody staining, post-fixation, and tissue storage.
Preparation of acid-washed glass coverslips for immunofluorescence microscopy v1
Authors: Ekstrom Jenna
Published: May 2024

Rizzardi Lab (Adapted from Schwer Lab- UCSF)
Marchantia thalli Transformation - Sulfadiazine Selection v1
Authors: Robinson Kayla
Published: May 2024

Here we provide a simplified protocol for Agrobacterium-mediated stable transformation of regenerating thalli of the model liverwort Marchantia polymorpha that involves sulfadiazine herbicide selection. The protocol is adapted from Kubota et al. (2013; https://doi.org/10.1271/bbb.120700), which should be referenced for further detail.
Western blot - alpha-synuclein v1
Authors: La Vitola Pietro , M. Szegö Eva
Published: May 2024

This protocol describes how to detect alpha-synuclein protein in mouse dorsal medulla oblongata tissue by western blot
Comparison of oral olanzapine versus oral ondansetron for prevention of postoperative nausea and vomiting in female patients undergoing laparoscopic cholecystectomy under general anaesthesia
Authors: HA Hema , A Smitha , GS Kumar , S Jayaram
Published: May 2024

Introduction: Postoperative nausea and vomiting is one of the significant problem in anaesthesia practice The incidence is even high following laparoscopic surgeries. 5HT3 receptor antagonists are routinely used to prevent postoperative nausea and vomiting (PONV). Olanzapine, an atypical antipsychotic drug with its activity on multiple receptor sites particularly at D2 and 5HT3 receptors, has potential antiemetic properties. This study aimed to compare the efficacy of ondansetron with olanzapine in prevention of PONV following laparoscopic cholesystectomy under general anaesthesia. Materials and methods: This randomized double blind controlled study was done by recruiting 120 female patients belonging to ASA I/II posted for laparoscopic cholecystectomy under general anaesthesia. Patients were assigned to one of the two groups. Group A received tablet Olanzapine 5mg, 4 hrs before surgery and Group B received tablet ondansetron 16mg 1hr before surgery. Postoperatively nausea, retching, vomiting complete response and sedation were assessed for 24hrs at the interval of 0-4hrs, 4-8hrs, 8-12hrs and 12-24hrs. Results: There was no statistical difference in the incidence of postoperative nausea, retching and vomiting between the groups at 0-4hrs, 4-8hrs. Statistical difference between the groups were seen at 8-12hr interval (nausea p=0.048, retching=0.042, vomiting p=0.042) and at 12-24 hr (nausea p=0.028, retching p=0.001, vomiting p=0.006). There was a significant difference in the use of rescue drug at 8-12hrs (6.7% patients required rescue drug in Group B whereas none required in Group B). Conclusion: Olanzapine 5 mg can be used safely and effectively for prophylaxis against PONV and is more effective in preventing PONV during the late postoperative period compared to ondansetron.
Evaluation of clinical and radiological correlation in blunt trauma abdomen
Authors: S Verma , S Aggarwal , A Verma , P Garg , SK Yadav , D Kumar , A Jangra
Published: May 2024

Background: Abdominal trauma is commonly encountered injury caused mainly due to road traffic accidents (RTA). The research aimed to study the cases of abdominal trauma, its different modes of presentation and correlation of radiological and clinical findings with operative findings in these patients. Material and methods: An observational study was conducted in a tertiary care institute. Hemodynamic instability and finding of shattered solid viscera on imaging and/or other injury requiring exploration were the criteria for surgical intervention. Radiological findings were then compared with the operative findings. In addition, clinical parameters were recorded till the patient was discharged and then analyzed. Results: A total of 62 patients presenting in Trauma Centre with an antecedent history of blunt abdominal trauma. Most common age group affected was 21-40 years and mean age was 30.4 + 11.56 years. Males were more affected and RTA was the most common mode of injury. Associated injuries included chest injuries (20.9%), limb fracture (19.35%) and soft tissue injuries (4.83%). Twenty patients were operated and rest of patients were managed conservatively. Sensitivity of USG in detecting liver and splenic injuries was 100% and specificity was 92.3% and 92.8% respectively. Sensitivity of CT for detecting injury to liver, spleen, renal, pancreas and small bowel was 100%, 83.3%, 100%, 100% and 83.3% and specificity was 100% in all injuries. Mortality rate in our study was 4.83%. Conclusion: High degree of suspicion and prompt screening by radiological investigations of patients should be done to rule out intraabdominal injury. Necessary investigations and early surgery whenever required is the key to management of blunt trauma patients.
The Digital Transformation of Russian Criminal Proceedings and the Role of the Prosecutor’s Office as the Organizer of such a Transformation
Authors: Voskobitova L. A.
Published: May 2024

To date, the Russian Federation does not have a single systematic digitalization program for all criminal proceedings. At the same time, digital technologies themselves are fragmentally penetrating the practice of law enforcement. That is why it is extremely important to investigate this issue, as well as to study the foreign, more successful experience of digitalization of criminal proceedings in other countries. The article discusses the issue of digital transformation of modern Russian criminal proceedings; the need of systemic and interdepartmental interaction to create a unified digital platform “Digital Criminal Justice” is substantiated, namely, government agencies, the bar and other interested agencies involved in criminal proceedings or related to them due to the law enforcement nature of their functions; the role of the Prosecutor General’s Office of the Russian Federation as the organizer and coordinator of interdepartmental interaction for the creation of such a platform and its use is argued. It seems that the only state body that, by virtue of its tasks, powers and place in criminal proceedings, is able to lead and implement a holistic and systematic digitalization of criminal proceedings in its substantive criminal procedural aspect is the Prosecutor General’s Office of the Russian Federation.
Multiple jury verdicts in the one case: approaches to solving the problem in legislation and judicial practice
Authors: Nasonov S. A.
Published: May 2024

The article, based on a study of judicial practice and comparative legal analysis of the legislation of the Russian Federation and a number of foreign countries, examines the problem of “multiplicity” of jury verdicts, i.e. the presence of two or more jury verdicts in one criminal case that meet the criteria of certainty and consistency and are subjects to proclamation. The author notes that the phenomenon of multiple jury verdicts is determined by the procedural error of the presiding judge, who recognizes that a certain and consistent jury verdict can not be pronounced. The article considers this phenomenon as a negative fact that contradicts the essential features of a jury trial. The author believes that solving the problem of multiple jury verdicts is possible, on the one hand, by clarifying and legalizing the grounds for recognizing the verdict as unclear or contradictory. On the other hand, there is a need for a significant modification of the procedural form of checking the jury’s verdict by the presiding judge for its clarity and consistency and giving him explanations to the jury in this regard. The author makes proposals for legislative reinforcement of the discussion between the presiding judge and the parties about the defects of the jury’s unannounced verdict, which should take place in the absence of the jury in a closed court hearing.