bluuebunny/crossref_metadata_2025 huggingface dataset:
Usuários do CAPS II: nutrição e qualidade de vida
Authors: De Carvalho Vivian Carla Honorato dos Santos , Krepsky Patricia Baier , Rocha Ana Myllena Pinto , Dos Santos Mariana Flores Silva
Published: November 2018

OBJETIVO: Avaliar o estado nutricional, o perfil clínico e a qualidade de vida (QV) de usuários do Centro de Atenção Psicossocial II (CAPS II) em Vitória da Conquista, BA. MÉTODOS: Foi realizado um estudo transversal com 120 usuários do CAPS II por meio de formulário contendo perguntas fechadas sobre dados sociodemográficos, qualidade de vida (QV) e autopercepção da saúde, assim como perguntas abertas sobre morbidade referida. Foi realizada também avaliação antropométrica (peso, altura e circunferência da cintura) para avaliar o estado nutricional. Para avaliação da QV foi usado o instrumento SF-12. A morbidade referida foi categorizada segundo a CID-10. RESULTADOS: Os usuários apresentavam idade média de 39,8 ± 12,48 anos, 64,5% eram mulheres, 55,8% eram solteiros e 71,7% não estavam aposentados. Em relação à QV, o componente mental sumarizado teve um resultado inferior quando comparado ao componente físico sumarizado. A autopercepção de saúde ruim alcançou 70,0% dos entrevistados; os transtornos mais prevalentes foram o transtorno de humor e esquizofrenia; 57,1% dos usuários apresentaram sobrepeso e obesidade e 65,5% dos participantes tiveram alteração da relação circunferência-estatura. CONCLUSÃO: Os usuários do CAPS II revelaram uma prevalência importante de excesso de peso, obesidade central, baixa qualidade de vida e uma autopercepção ruim da sua saúde. Compreender essas questões tornasse extremamente relevante para pensarmos em políticas locais de atendimento e organização dos CAPS, com uma maior interlocução com os serviços de atenção primária dos municípios, promovendo uma atenção integral e promotora de saúde.
Lösemi patogenezinde miRNA 15a/16–1 lokus delesyonlarının ve Protein L-isoaspartate O-methyltransferase (PCMT1) enziminin rolü
Authors: BİTERGE-SÜT Burcu , BALI Dilara Fatma
Published: November 2018

Kanser, ülkemizde ve dünyada sıklıkla görülen hastalıklardan birisidir. Karsinojenez
sırasında büyük değişimlere uğrayan hücresel gen ifadesi profili DNA dizisi
dışında DNA metilasyonu, kodlanmayan RNA’lar (ncRNA), RNA interferansı (RNAi),
histon varyantları ve post-translasyonel histon modifikasyonları gibi başkaca epigenetik
mekanizmalar tarafından da kontrol edilebilmektedir. Bununla birlikte; mutasyonlar,
delesyonlar ve translokasyonlar gibi çeşitli sebepler sonucu ortaya çıkan
genetik anomaliler kanser oluşumunda ve tedaviye verilen yanıtta önemli rol
oynamakta ve klinikte, kanser alt tiplerinin belirlenmesinde incelenmektedir. 13.
kromozomun q kolunda bulunan miRNA 15a/16-1 lokusu delesyonlarının Mcl1, Bcl2,
Ets1, Jun gibi kanser ile ilişkili birçok geni etkilediği gösterilmiştir.
Ayrıca, bu miRNA’ların regüle ettiği Protein L-isoaspartate O-methyltransferase
(PCMT1) proteinin apoptoz yolağı üzerindeki etkisi dolayısıyla karsinojenez
üzerinde önemli rol oynadığı birçok çalışma ile vurgulanmıştır. Literatürde
miRNA 15a/16-1 lokusu ve p53 arasında hücre proliferasyonu ve büyümesini
sağlayan sinyallerin üretimini düzenleyen bir feedback döngüsünün varlığı
tartışılmaktadır. Yapılan çalışmalar, miRNA 15a/16-1 lokusunu tümör baskılayıcı
gen bölgesi, PCMT1’i ise onkogen olarak tanımlamaktadır. Buna paralel olarak, miRNA
15a/16-1 lokusunu da içeren 13q14.3 bölgesi delesyonu birçok lenfoid ve
miyeloid lösemi alt türlerinde tespit edilmiş olup, klinikte rutin taramalara
dahil edilme potansiyeline sahiptir. Lösemi hastalarında 13q14.3 bölgesi delesyonunun
araştırılması hastalığın alt tiplerinin sınıflandırılmasını ve hatta
uygulanacak tedavi rejimini yönlendirebilecek önemli sonuçlar elde edilmesini
sağlayabilecektir.
Analysis of agreement of assessment tools of range of motion in the elderly
Authors: Pires-Oliveira Deise Aparecida de Almeida , Freitas Rosemari Queiroz , Júnior Abdallah Achour , Oliveira Laís Campos de , Oliveira Raphael Gonçalves de , Oliveira-Silva Iranse , Soares Viviane , Oliveira Rodrigo Franco de
Published: November 2018

Background: Considering the growth of the elderly population and the typical declines in the aging process on physical capacities such as flexibility, it is necessary to understand how different assessment instruments are able to measure joint range of motion. Objective: To verify the agreement between the goniometer and fleximeter instruments in the evaluation of the range of motion of the hip, knee and ankle joints of elderly women. Methods: The study evaluated a total of 138 elderly women, mean age of 70 years (± 5.49). The goniometer and the fleximeter were used to verify the range of motion of the hip flexion, knee flexion and ankle dorsi- and plantar‐flexion. For the analysis were used the Intraclass Correlation Coefficient (ICC) and Bland-Altman plot, with confidence intervals of 95%. Results: The ICC values showed excellent agreement between the instruments, while the Bland-Altman plots presented a low risk of bias for all the regions evaluated (hip flexion: ICC= 0.99, bias= 1.19; knee flexion: ICC= 0.99, bias= -0.16; ankle dorsiflexion: ICC= 0.91, bias= -0.60; ankle plantar-flexion: ICC= 0.96; bias= -0.81). Conclusion: The results showed an excellent agreement between the data provided by the goniometer and fleximeter instruments on the evaluation of the range of motion of the hip flexion, knee flexion and ankle dorsi- and plantar-flexion, indicating that both provide similar results in the elderly.
Ó D-us
Authors: Poenaru Vlad Eugen
Published: November 2018

Ó D-us
Intertextualidade irônica em Jn 3:7-4:2
Authors: Martins Lucas Alamino Iglesias , Da Silva Luciano Geraldo Mateus
Published: November 2018

Este artigo visa examinar alguns aspectos literários em Jonas, bem como verificar as relações intertextuais entre o texto de Jn 3:7-4:2 e Êx 32-34, analisando os aspectos irônicos presentes nas conexões entre as duas narrativas, principalmente, na relação entre os profetas Jonas e Moisés, no qual se destaca a forma irônica com a qual o autor apresenta as ações do profeta.
A Alberto Dines
Authors: Pereira José Mario
Published: November 2018

A Alberto Dines
Jacob, Esaú e a sopa
Authors: Grzybowski Adam , Goldman Luis
Published: November 2018

Jacob, Esaú e a sopa
Shangrilá
Authors: Scliar-Cabral Leonor
Published: November 2018

Shangrilá
Design of 35kV Box Substation
Authors: Lu Zhiyong
Published: November 2018

In China, the current use of box-type substation is widespread, all walks of life are in use, box-type substation, alsoknown as outdoor complete substation, is the high voltage power, transformer buck, low voltage distribution and otherfunctions organically combined, It is suitable for use in economic development zones where the load is concentrated,and it is suitable for the economic development zone, the factory, the factory building, the factory building, the factorybuilding, the factory building, Mines, residential quarters and other urban public facilities, the user can be based ondiff erent conditions of use, load level selection box-type substation.
Design of Battery Parameter Analysis Device Based on Labview
Authors: Pan Sihong
Published: November 2018

Based on the design of labview battery parameter analyzer, this problem is a problem worthy of further study. Themain content of this thesis is to use labview software to design a program, through DAQmx will be in the physicaldata (the battery of various parameters, such as: voltage, current, etc.) into the computer, through the already designedprogram to measure various parameters of the battery. My main goal this time is to measure the battery's power.Therefore, I need to measure the actual circuit by the battery voltage changes, current changes, and the time spent bythe software in the program analysis to calculate the battery actually have the power. Not only to calculate the totalpower, but also to calculate the power per minute per second, and through the chart displayed. The biggest feature ofthis topic is the theoretical design is more important, hardware devices and devices is not too complicated, of course,only relatively speaking, so the biggest feature of this topic is that I designed the software program, the main functionis refl ected in the program Among them, the hardware device only played a supporting role.
Ege Üniversitesi Gözlemevi’nin Gökyüzü Parlaklık Ölçümleri
Authors: DEVLEN Ahmet
Published: November 2018

Büyük şehirler sahip oldukları
ışıkla geceleri ışıltılıdır ve muhteşem görünürler. Bu ışıltılı şehir ışıkları
kamu alanlarındaki aydınlatmalar, sokak aydınlatmaları, reklam panoları, bina
dış aydınlatmaları ve ticari aydınlatmalardan oluşmaktadır. Bu görkemli görüntü
yapay ışıkların uygunsuz ve aşırı kullanılmasından kaynaklanmaktadır. Buna ışık
kirliliği denir. Yıldızlardan gelen zayıf ışıkları gözleyebilmek için karanlık,
nemsiz, ışık kirliliği ve hava kirliliği olmayan yerlere ihtiyacımız vardır.
Gökcisimlerinden gelen bu zayıf ışığın incelenmesi sahip olduğumuz teknolojik
kabiliyetlerin yanı sıra ışık kirliliği olmayan gözlemevlerine sahip olmamıza
bağlıdır. Bu çalışmada Ege Üniversitesi Gözlemevi’nde gece gökyüzü parlaklık
ölçümleri yapılmıştır. 2010 yılında, zenit açısı z < 60° için
gökyüzü parlaklığı tüm azimut açılarında 19 kadir civarında ölçülmüştür. 2017
yılında zenit açısı 35°
< z < 60°
için, gökyüzü parlaklığında azimut açısı 240° < a < 270°,  270° < a < 360° ve 0° < a
< 30° arasında,
sırasıyla, 0.4, 0.8 ve 0.25 kadirlik bir artış olduğu tespit edilmiştir. Bu
parlaklık artışı, gözlem süresinin yaklaşık 1.5 saat kısalmasına neden
olmuştur. Bu ölçümler Ege Üniversitesi Gözlemevi’ndeki ışık kirliliğinin hızla
arttığını ve astronomik gözlemlerin sınırlandığını göstermiştir.
Friction Behavior of TiAlN, AlTiN and AlCrN Multilayer Coatings at Nanoscale
Authors: ÖZKAN Doğuş
Published: November 2018

In this study, 3.5 μm
thick TiAlN, AlTiN, and AlCrN multilayer coatings were deposited on
the H13 steel surface by physical vapor deposition (PVD) method. Friction
behavior of these coatings was
investigated by friction force microscopy for the first time at nanoscale in the literature. Friction force
measurements were performed with the atomic
force microscopy lateral force mode at various loads. Results showed that the AlTiN coating had three times lower COF value
than the TiAlN and AlCrN coatings due to the lower surface energy. It was
observed in this study that Amonton’s law was valid for the COF evolution at
the nanoscale.
A Computational Method for Volterra Integro-Differential Equation
Authors: ÇİMEN Erkan
Published: November 2018

In this paper, we examine the
initial value problem for a linear first order Volterra integro-differential
equation. In order to solve the problem computationally, we present a novel
finite difference method, which is based on the method of integral identities
with the use of the basis functions and interpolating quadrature rules with
remainder term in integral form. Furthermore, as a consequence of error
analysis the method is proved to be first-order convergent in the discrete
maximum norm. Finally, an example is provided to support our theoretical
results.
Gama Radyasyonunun, Kalp-Damar Tedavisinde Kullanılan Losartan Potasyum ve İndapamid İlaçlarında Oluşturduğu Paramanyetik Merkezin EPR Spektroskopisi ile İncelenmesi
Authors: OSMANOĞLU Yunus Emre
Published: November 2018

Bu
çalışmada, losartan potasyum ve indapamide ilaçlarında gama radyasyonu ile
oluşturulan serbest radikallerin doğası elektron paramanyetik rezonans (EPR)
spektroskopisi kullanılarak oda sıcaklığında belirlenmiştir. Bu örneklerin EPR
spektrumları sırasıyla CHĊHCH3 ve ĊHCHCH3NH radikallerine atfedilmiştir. Serbest
radikallerin aşırı ince yapı sabitleri ve g-değerleri hesaplanmıştır. EPR
ölçümleri radyasyondan sonra oluşan paramanyetik merkezin kararlılığı ve spin
yoğunluluğunun absorplanan radyasyonun dozuna bağlı olduğunu göstermiştir. Her
iki örnekte oluşan paramanyetik merkezler örneklerin kimyasal yapısı göz önüne
alınarak belirlenmiştir. İki materyalin manyetik özellikleri ve paramanyetik
merkezin mümkün yapısı bu çalışmada tartışılmıştır.
Effective Atomic Number and Electron Density Determination of Some Amino Acids by Using Scattering Intensity Ratio of 59.54 keV Gamma Rays
Authors: TURŞUCU Ahmet
Published: November 2018

In this study the specific atomic arguments have
been determined for F-Glycine (C2H5O2N),
Alenine (L, D) (C3H7O2N), Leucine (L, D) (C6H13O2N),
L-Proline (C5H9O2N) amino acids. The calculation procedure of the experimental values of atomic
parameters was carried out by using scattering intensity ratios of γ-rays.
These γ-rays were obtained from 5 Ci 241Am annular radioactive
source.  In traditional studies, these
arguments were determined by transmission technique. The scattered γ-rays were
counted by using an HPGe semiconductor detector. Our detecting system was connected
to a separate amplifier and an Accuspec card. Theoretical values of related
atomic parameters for amino acid targets were calculated and cross checked with
our experiential values. Our deliberated values are in good concordance with
theoretical calculations.
Estratégia para Redução da Corrente Eficaz em Motores BLDC Operando sob Falta de Fase Visando Amenizar o Desgaste do Motor
Authors: Liberato Cesar , Dezuo Tiago , Oliveira José de , Nied Ademir
Published: November 2018

Esse trabalho apresenta uma estratégia de redução de corrente eficaz das fases saudáveis para motores brushless DC (BLDC) operando em falha de abertura de fase, evitando a degradação do motor e permitindo o desligamento seguro. Após o diagnóstico de uma falha de fase aberta, através de um algoritmo capaz de detectar e identificar falhas e retornos de fases do motor BLDC em tempo real, uma ação corretiva dividida em três etapas é proposta. Primeiro, o modo de operação tradicional Six-Step com condução em 120? elétricos é alterado para um novo modo de operação que utiliza as duas fases saudáveis em condução de 180? elétricos para reduzir a perda de torque em falha. Segundo, é imposta uma forma trapezoidal para a referência de corrente em sincronismo com as tensões induzidas entre as fases saudáveis visando reduzir o nível de corrente e, consequentemente, melhorar a eficiência do motor. E terceiro, reduz-se a banda passante da malha de velocidade para reduzir a influência das oscilações de velocidade em falha no controlador. Os resultados experimentais apresentados mostram que o modo de operação com a estratégia de redução de corrente proposta possibilita uma redução aproximada de 25% na corrente eficaz e de 40% na variação de temperatura do motor, em comparação ao modo de operação usual do motor BLDC em falha de fase sem a estratégia proposta.
CONFEDERATE MONUMENTS, PLANTATION-MUSEUMS AND SLAVERY: Race, Public History, and National Identity
Authors: SMALL STEPHEN
Published: November 2018

Abstract: My primary focus in this article is on sixteen slave cabins incorporated into three heritage tourism sites in Natchitoches, North West Louisiana. The sites are Oakland Plantation, Magnolia Plantation and Melrose Plantation. How is national identity expressed and articulated at these sites; and how does consideration of slave cabins provide opportunities for highlighting and questioning issues of national identity? I seek to persuade the reader that consideration of the current representations of the slave cabins can expand our analytical intervention and broaden our understanding of the promotion of national identity at these sites.Keywords: Confederate monuments. Plantation-museums. Slavery.  MONUMENTOS CONFEDERADOS, MUSEUS DE PLANTAÇÃO E ESCRAVIDáƒO:  Raça, História Pública e Identidade NacionalResumo: Meu foco principal neste artigo é sobre dezesseis cabanas de escravos incorporadas em três locais de turismo de patrimônio em Natchitoches, no noroeste da Louisiana. Os locais são Oakland Plantation, Magnolia Plantation e Melrose Plantation. As questões que perpassam este trabalho são: Como a identidade nacional é expressa e articulada nesses sites? E como a consideração das cabanas de escravos oferece oportunidades para destacar e questionar questões de identidade nacional? Procuro convencer o leitor de que a consideração das atuais representações das cabanas escravas pode expandir nossa intervenção analá­tica e ampliar nossa compreensão da promoção da identidade nacional nesses locais.Palavras-chave:  Monumentos confederados. Museus de plantação. Escravidão.  MONUMENTOS CONFEDERADOS, MUSEOS DE PLANTACIÓN Y ESCLAVITUD:  Raza, Historia Pública e Identidad NacionalResumen: Mi enfoque principal en este artá­culo es sobre dieciséis cabañas de esclavos incorporadas en tres sitios de turismo patrimonial en Natchitoches, en noroeste de Louisiana. Los sitios son Oakland Plantation, Magnolia Plantation y Melrose Plantation. Las cuestiones que atraviesan este trabajo son: ¿Cómo se expresa y se articula la identidad nacional en estos sitios? y ¿cómo la consideración de las cabañas de esclavos ofrece oportunidades para destacar y cuestionar los problemas de identidad nacional? Intento persuadir al lector de que la consideración de las representaciones actuales de las cabañas de esclavos puede ampliar nuestra intervención analá­tica y ampliar nuestra comprensión de la promoción de la identidad nacional en estos sitios.Palabras clave:  Monumentos Confederados. Museos de plantación. Esclavitud.
MEMORY, PATRIMONIALISATION AND CULTURAL POLICIES IN AFRICA - Entrevista com Ibrahima Thiaw
Authors: BARBOSA VIVIANE DE OLIVEIRA
Published: November 2018

MEMÓRIA, PATRIMONIALIZAÇÃO E POLáTICAS CULTURAIS NA áFRICA  INTERVIEW  MEMORIA, PATRIMONIALIZACIÓN Y POLáTICAS CULTURALES EN áFRICA
Gerónimo Borao. Historia de la Universidad de Zaragoza
Authors: Vicente y Guerrero Guillermo
Published: November 2018

Este artículo reseña: Gerónimo Borao. Historia de la Universidad de Zaragoza. Edición y estudio introductorio de Carlos Forcadell. Zaragoza, Institución Fernando el Católico y Prensas Universitarias de Zaragoza, 2017, xli pp. + 209 pp.
Francisco Murillo Ferrol y los primeros estudios de ciencia política y sociología en la Universidad de Valencia = Francisco Murillo Ferrol and the First Studies of Political Science and Sociology at the University of Valencia
Authors: Palao Gil Javier
Published: November 2018

Resumen: Francisco Murillo Ferrol fue catedrático de derecho político en la Universidad de Valencia desde su acceso a la cátedra, en 1952, hasta su marcha a la Universidad de Granada en 1961. Fue el primer catedrático estable que tuvo la disciplina en Valencia desde 1932. Cuando llega, es un profesor formado en la filosofía del derecho y que había realizado algunas reflexiones sobre la teoría del Estado desde perspectivas históricas y clásicas. Sus ocho años y medio en Valencia fueron de intensa actividad: dirigió el colegio mayor “Luis Vives”; participó intensamente en la vida académica de la Facultad; impulsó un Seminario interdisciplinar de ciencias sociales centrado en la sociología y la ciencia política, cuyas corrientes principales en Europa y América empezó a introducir; creó una gran biblioteca sobre estas materias; animó un primer grupo de discípulos; etc. El presente estudio muestra toda esa actividad, al tiempo que hace una descripción de los principales rasgos de la personalidad del profesor, como su tolerancia política y personal, su vigorosa personalidad intelectual, caracterizada por una actitud crítica radical, su escepticismo rayano en el pesimismo y, sobre todo, su firme vocación docente, que le llevó a ser definido como “un maestro en tiempo de patronos”.Palabras clave: Universidad franquista, Murillo Ferrol, derecho político, ciencia política, sociología.Abstract: Francisco Murillo Ferrol was a professor of political law at the University of Valencia from his access to the chair in 1952, until his departure to the University of Granada in 1961. He was the first stable profesor this discipline had in Valencia since 1932. When arriving, he was a professor trained in philosophy of law who had done some reflections on the theory of the State from historical and classical perspectives. His eight and a half years in Valencia show an intense activity: he was the director of the college “Luis Vives”; he participated intensely in the academic life of the faculty; he promoted an interdisciplinary seminar on social sciences focused on sociology and political science, whose main currents in Europe and America he began to introduce; he created a large library on these matters and encouraged a first group of disciples; etc. The present study shows all this activity, as well as a description of the main features of the professor’s personality, such as his political and personal tolerance, his vigorous intelectual personality, characterized by a radical critical attitude, his scepticism bordering on pessimism and, above all, his strong vocation towards teaching, which led him to be defined as “a master in an age of bosses”.Keywords: Francoist university, Murillo Ferrol, political law, political science, sociology.
Reconsider deschooling: Alternative towards more accessible and inclusive education
Authors: Soegiono Agie Nugroho , Anis Aulia , Maulida Saskia Rizqina
Published: November 2018

This essay discusses deschooling concept as an alternative learning delivery method to achieve education for all. We argue that the deschooling idea, first introduced by Illich before the era of the Internet, has become relevant in relation to today’s education challenges. What we mean by deschooling in this paper is not the abolishment of the schooling system. Instead, the recall of deschooling discourse aims to provide more recognition of learning activities outside of the school setting. The learning webs, a key enabler in deschooling discourse, are realistic when implemented with the help of 21st century’s technology. The argument in this paper utilised an in-depth literature review and discourse analysis in the deschooling debate. To strengthen our argument, we have provided three case studies in the form of informal learning, non-formal learning and e-learning related to deschooling initiatives. Based on our findings, we can conclude that deschooling society is certainly viable. The principles used in deschooling, such as ﬂexibility, inclusiveness, adaptability and personalisation, are alternatives for everyone to have freedom of access, use, copy, and modify learning resources. We also found that there may be possible challenges, including the limitation of self-directed learning, the pitfall of institutionalised capital and a lack of social interaction.
The impact of clean lifestyle health promotion on the attitude, motivation, and behaviour of village health cadres
Authors: Solehati Tetti , Rahmat Agus , Kosasih Cecep Eli , Hidayati Nur Oktavia
Published: November 2018

Pangandaran is a popular tourism destination in West Java, which is annually visited by a high number of foreign and domestic tourists. It has set itself the vision of gaining the title ‘Healthy Village’. However, Pangandaran beach is still fighting the problem of waste, which is easily found along the coast. Thus, disease is mushrooming due to the lack of a Clean Lifestyle (Perilaku Hidup Bersih Sehat/PHBS) and the low awareness of PHBS in the Pangandaran local community. The eﬀorts undertaken to overcome the problem of infectious disease due to the lack of PHBS require great support from various parties such as health service centres and via community participation and the role of cadres, who also manage the Community Health Centres (Pos Pelayanan Terpadu/Posyandu). The study aims to determine the eﬀect of the health promotion of PHBS on the attitude, motivation, and behaviour of the health cadres. The study was quasi-experimental, involving a pre-test and post-test design. The study was conducted in Pangandaran Village, Pangandaran Regency. This research involved the health cadres because they are the closest person to the community and they also run a health program. In addition, they are reliable people when it comes to overcoming health problems in the community. The total population of health cadres in Pangandaran Village amounted to 28 people, via total sampling. The instruments used in this study included a questionnaire, observation sheet, and a checklist. The data analysis used univariate and bivariate analysis. The result showed that the mean score of attitude ranged from 65.11 to 74.71 (p = 0,000), the mean score of motivation was 37.39 to 40.71 (p = 0,000), the mean score of genital hygiene behaviour was 67.96 to 80.61 (p = 0,000) and the mean score of the behaviour of CTPS was significant at 32.25 to 35.71 (p = 0,000). This study found there to be significant diﬀerence in the mean attitude, motivation and behaviour of the health cadres before and after the intervention period.
Primary components in shaping koperasi masjid’s participation level: Employing a principle component analysis approach
Authors: Fitriani Fitriani , Sudiyo Sudiyo , Berliana Dayang , Yuniarti Evi
Published: November 2018

Koperasi masjid present themselves as a part of muamalah through Sharia economic facilitation. This study was conducted to analyse the cooperative members’ participation level in relation to the implementation of a cooperative business program. A survey using a case study approach was conducted at koperasi Masjid Hafshotul Iman, Masjid Taqwa and Masjid Darul HikmahThe survey employed a purposive sampling method with the participation of the cooperative’s management (chairman, secretary, and treasurer) and the masjid’s members. Ten respondents were purposively chosen from each mosque and a total 30 respondents were acquired. The distributed questionnaire was a closed one, measured with a Likert scale. The results were analysed using factor analysis and the Principal Component Analysis approach (PCA). Based on the results of the factor analysis, the members’ participation level in cooperative service can be classified into three primary factors. Some of the variables displayed a strong correlation with Factor 1, namely motivation, management performance, RAT performance, and supervisor performance. The second primary factor was formed by activeness in participating in cooperative activities. Lastly, the third primary factor encompassed three variables with a strong correlation, namely age, education, and membership duration.
The business management of the village government in managing Village Owned Enterprise
Authors: Prafitri Nikki , Setyoko Paulus Israwan , Puspita Dyah Retna
Published: November 2018

Local Government business management through a Village Owned Enterprise is a new public management application. The Village government’s business is carried out by applying business techniques, values and principles. The purpose of the Village Owned Enterprise is to increase the village’s original income and economy. The diﬀerences involved in the success of the Village-Owned Enterprise management is triggered by diﬀerences in the application of government business principles, consisting of several aspects including the business plan, capital, accountability, transparency, reporting, corporate accounting and the payroll system. This research focused on the application of government business principles in relation to the management of the Village Owned Enterprise. The research used a qualitative research method and interactive data analysis method. Furthermore, the research was conducted in two villages; Serang Village, Karangreja Subdistrict, Purbalingga Regency and Pernasidi Village, Cilongok Subdistrict, Banyumas Regency. The research findings showed that the involvement of the village head in the preparation and socialisation of the business plan, the delegation of authority in relation to capital, the commitment to implementing transparency, the control over the officer's accountability and reporting, audits on accounting and the participation and cooperation from various stakeholders to motivate the officers in managing Village-Owned Enterprise for village welfare. The listed are the preconditions of village government business management through the Village-Owned Enterprise. Based on the funding of the phenomenon in the field regarding village business management through the Village Owned Enterprise, there are several recommendations to strengthen the management of the economic institution itself.
Formalizing the Concept of “Build Back Better” Based on the Global Forum on Science and Technology for Disaster Resilience 2017 WG4
Authors: Tamura Keiko , Rafliana Irina , Kovacs Paul ,   Risk Management Office, Niigata University
 8050 Ikarachi-Nino-cho, Nishi-ku, Niigata 950-2181, Japan,   Indonesian Institute of Science, Research Center for Oceanography (LIPI), Jakarta Utara, Indonesia,   Institute for Catastrophic Loss Reduction, Ontario, Canada
Published: November 2018

This paper outlines the process of formalizing Priority Action 4, “Build Back Better,” in recovery, rehabilitation, and reconstruction in Sendai Framework for Disaster Risk Reduction 2015–2030. We propose this formalization by introducing the background and existing framework of recovery, rehabilitation, and reconstruction, a case-study of Post-War Japan, and the outcome of discussions implemented in the Global Forum on Science and Technology for Disaster Resilience 2017 held at the Science Council of Japan in Tokyo on November 23–25, 2017. This paper also summarizes the results of discussions regarding further development of Priority Action 4.
Strengthening National Platforms for Effective Use of Science and Technology for Disaster Risk Reduction
Authors: Nishikawa Satoru ,   Disaster Mitigation Research Center, Nagoya University
 Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
Published: November 2018

The Guiding Principles of the Sendai Framework for Disaster Risk Reduction 2015–2030 state that “(a) Each State has the primary responsibility to prevent and reduce disaster risk, including through international, regional, subregional, transboundary and bilateral cooperation,” and “(b) Disaster risk reduction requires that responsibilities be shared by central Governments and relevant national authorities, sectors and stakeholders, as appropriate to their national circumstances and systems of governance.” The need for a multi-sectoral national mechanism for disaster reduction was recognized during the International Decade for Natural Disaster Reduction (IDNDR) 1990–2000, and the responsibility was inherited to the International Strategy for Disaster Reduction (ISDR). The United Nations General Assembly Resolution 56/195, which was adopted in December 2001, called upon Governments to establish national platforms or focal points for disaster reduction. At the Global Forum on Science and Technology for Disaster Resilience, held in Tokyo in November 2017, a plenary session focusing on National Platforms was organized and ways for the effective integration of the knowledge and expertise available within the national science and technology community in the national disaster risk reduction activities were discussed. This paper examines how the idea of national platform for disaster reduction evolved since the beginning of IDNDR. This paper further reviews and illustrates the previous discussions on National Platforms from 2005 to 2015 as well as existing guidelines on National Platforms. Based on the discussions carried out during the Forum, five recommendations adopted by the Forum are introduced.
Analysis of Complexities in Natech Disaster Risk Reduction and Management: A Case Study of Cilegon, Indonesia
Authors: Lestari Fatma , Pelupessy Dicky , Jibiki Yasuhito , Putri Fiori Amelia , Yurianto Ahmad , Widyaputra Gama , Maulana Sony , Maharani Cynthia Febrina , Imamura Fumihiko ,   Disaster Research and Response Centre, Universitas Indonesia ILRC Building, level 2, Kampus Universitas Indonesia, West Java, Depok 16424, Indonesia,   Department of Occupational Health and Safety, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia,   Faculty of Psychology, Universitas Indonesia, Depok, Indonesia,   International Research Institute of Disaster Science (IRIDeS), Tohoku University, Miyagi, Japan,   Health Crisis Centre, Ministry of Health, Indonesia, Jakarta, Indonesia,   Marketing and Directorate, Pertamina Oil & Gas Company, Jakarta, Indonesia,   Tangerang City Disaster Management Agency, Banten, Indonesia
Published: November 2018

Complex disasters may occur as a result of a natural disaster combined with an industrial or a technological disaster. These are also called “natural-hazard triggered technological (natech) disasters.” Currently, there is increasing awareness of the hazards of these natech disasters. Natural disasters could trigger a technological disaster including oil spills and the release of hazardous and flammable materials and toxic chemicals, causing cascading events. The impact of the damage on public health and safety could be catastrophic, as it may result in massive loss of life, environmental destruction, and asset and property loss. Moreover, it could cause business disruptions and affect a country’s reputation. This paper describes a case study on the application of disaster risk reduction and management for natech disasters in Cilegon, Indonesia. We introduce the analysis of risk assessment conducted in Cilegon, the preparedness of the Cilegon City government, a contingency plan that has been developed, and the state of disaster preparedness in industrial zones. Natural and technological disaster risks as well as several emergency preparedness efforts are discussed and multiple stakeholders are identified. The paper serves as a foundation for future research to address natech disasters.
Anesthetics to Prevent Lung Injury in Cardiac Surgery (APLICS): A protocol for a randomized, controlled trial
Authors: O’Gara Brian P. , Subramaniam Balachundhar , Shaefi Shahzad , Mueller Ariel , Banner-Goodspeed Valerie , Talmor Daniel
Published: November 2018

Background Patients undergoing cardiac surgery with cardiopulmonary bypass are at an increased risk of developing postoperative pulmonary complications, potentially leading to excess morbidity and mortality. It is likely that pulmonary ischemia-reperfusion (IR) injury during cardiopulmonary bypass is a major contributor to perioperative lung injury. Therefore, interventions that can minimize IR injury would be valuable in reducing the excess burden of this potentially preventable disease process. Volatile anesthetics including sevoflurane have been shown in both preclinical and human trials to effectively limit pulmonary inflammation in a number of settings including ischemia-reperfusion injury. However, this finding has not yet been demonstrated in the cardiac surgery population. The Anesthetics to Prevent Lung Injury in Cardiac Surgery (APLICS) trial is a randomized, controlled trial investigating whether sevoflurane anesthetic maintenance can modulate pulmonary inflammation occurring during cardiac surgery with cardiopulmonary bypass, and whether this potential effect can translate to a reduction in postoperative pulmonary complications. Methods APLICS is a prospective, randomized controlled trial of adult cardiac surgical patients. Subjects will be randomized to receive intraoperative anesthetic maintenance with either sevoflurane or propofol. Patients in both groups will be ventilated according to protocols intended to minimize the influences of ventilator induced lung injury and hyperoxia. Bronchoalveolar lavage (BAL) and blood sampling will take place after anesthetic induction and between two to four hours after pulmonary reperfusion. The primary outcome is a difference between groups in the incidence of inflammatory lung injury, defined by an increase in post-bypass BAL concentrations of TNFα. Secondary outcomes will include additional relevant BAL and systemic inflammatory markers and the incidence of postoperative pulmonary complications. Discussion APLICS investigates whether anesthetic choice can influence lung inflammation and pulmonary outcomes following cardiac surgery with cardiopulmonary bypass. A positive result from this trial would add to the growing body of evidence describing the lung protective properties of the volatile anesthetics and potentially reduce unnecessary morbidity for cardiac surgery patients. Trial Registration ClinicalTrials.gov identifier NCT02918877, registered on September 29, 2016. KEYWORDS Inflammatory lung injury, volatile anesthetics, cardiac surgery, postoperative pulmonary complications, TNFα.
A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Huang Qi Gui Zhi Wu Wu Tang granules in patients with rheumatoid arthritis
Authors: Liu Yang , Wang Yi-Ru , Xi Zhi-jie , Yu Yang , Liu Li , Mao Jian-chun , Xiao Lian-bo , Gu Xiao-hua , Yao Min , Cui Xue-Jun , Shi Qi , Wang Yong-Jun , Liang Qian-Qian
Published: November 2018

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by swelling, pain, and synovial damage. Effective methods lack in the treatment of RA. A traditional prescription in use for thousands of years in China, Huang Qi Gui Zhi Wu Wu Tang (HQGZWWT) granule is still chosen to relive pain and prevent joint malformation in RA patients. However, no evidence-based medical research has been organized to assess the effectiveness and safety of HQGZWWT granules for RA.
Methods/design: We will conduct a multicenter, randomized, double-blind, placebo-controlled clinical trial to determine whether HQGZWWT granules can relieve pain and protect joints. We will randomly divide 120 patients with active arthritis for 3 months. Main measurements include ratio of 50 of ACR (American College of Rheumatology), change of DAS (28) from baseline to 3 months, and SHARP scores of van der Heijde from baseline to 12 months. SecondarymeasurementsincludeACR20, ACR70, Health Assessment Questionnaire-Disability Index (HAQ-DI), arthritis pain score, and Patient Global Assessment of Arthritis. The time points are set as baseline, 2 weeks, 1 month, 2 months, 3 months, 6 months and 12 months. In addition, the rate of change (score) in the ACR50 and DAS28 from the baseline to 2-week, 1-month, 2-month, 6-month, and 12-month follow-up are also the secondary outcome measures.
Discussion: The findings of this research will elucidate the efficacy and safety of HQGZWWT granules and provide an alternative treatment for RA. In addition, our data will benefit the clinical decision-making on active RA and possibly be incorporated into future guidelines.
Trial registration: ClinicalTrials.gov ID: NCT03593837.

Keywords: Traditional Chinese medicine, Huang Qi Gui Zhi wu wu granules, placebo, active rheumatoid arthritis, multicenter, randomized controlled trial.
LESS IS MORE? – A PILOT RCT OF FLUID STRATEGY IN CRITICALLY ILL CHILDREN WITH ACUTE RESPIRATORY TRACT INFECTION
Authors: Ingelse Sarah A. , Geukers Vincent G. , Dijsselhof Monique E. , Lemson Joris , Bem Reinout A. , Woensel Job B. van
Published: November 2018

Background: Fluid overload is common in critically ill children and is associated with adverse outcome. Therefore, restricting fluid intake may be beneficial. This study aims to pilot the feasibility of a RCT comparing a conservative to a standard, more liberal, strategy of fluid management in mechanically ventilated (MV) pediatric patients with acute respiratory tract infection (ARTI).
Methods: This is a pilot RCT and feasibility study in a single, tertiary referral pediatic intensive care unit. Twenty-three children receiving MV for ARTI, without ongoing hemodynamic support, admitted to the PICU of the Emma Children’s Hospital/Amsterdam UMC between 2016-2018 were included. Patients were randomized to a conservative (<70% of normal intake) or standard (>85% of normal intake) fluid strategy, which was kept throughout the period of MV.
Results: Primary endpoints were adherence to fluid strategy and safety parameters such as calorie and protein intake. Secondary outcomes were cumulative fluid intake (CFI) and cumulative fluid balance (CFB) on day 3. In the conservative group, in 75% of the MV days patients reached their target fluid intake. Median calorie intake over all MV days was 67.8 [53.1-75.2] kcal/kg/day and 1.6 [1.3-1.7] gr protein/kg/day (no difference between groups). No adverse effects on hemodynamics or electrolyte imbalances were noted. Mean CFI on day 3 was 262.3 (±58.9) ml/kg in the conservative group vs. 360.5 (±52.6) ml/kg in the standard fluid group (p<0.001), which did not result in a lower CFB.
Conclusions: A conservative fluid strategy in MV children with ARTI seems feasible, without limiting metabolic needs. However, in our study a conservative fluid strategy surprisingly did not reduce the degree of fluid overload. This pilot study aids the design and sample size calculation of a future larger multicenter RCT, in which we need to redefine the target fluid strategy, possibly by even further fluid restriction and early initiation of active diuresis.

Trial registration: ClinicalTrials.gov, NCT02989051. Registered 12 December 2016 - Retrospectively registered, https://www.clinicaltrials.gov/ct2/show/NCT02989051
Fabry disease causes angiitis of the central nervous system:a case report
Authors: Kong De-Zheng , Lian Ya-Hui , Wang Lin-Jing , Wang Chun-Mei , Meng Yang-Yang , Zhou Hong-Wei
Published: November 2018

Background: Fabry disease is very rare and often delayed in diagnosis. Described herein are Fabry disease causes angiitis of the central nervous system. MRI black blood sequence has a unique advantage in showing vascular wall. It can clearly show the angiitis.
Case presentation: A 27-year-old man came to our hospital for treatment because of "diplopia 6d". The patient was eventually diagnosed with Fabry disease causes angiitis of the central nervous system by a series of examinations. Then，we treated patient with hormones and the symptoms relieved. Two months later，the initial vasculitis was gone，but the new vasculitis appeared. Four months later，the last lesion disappeared，but the new lesion appeared.
Conclusions: This case prompts the clinician should use MRI black blood sequence scan in time when young patients have repeated strokes and the lesions are migratory. If vasculitis is found and other systemic lesions are combined，we should think of the possibility of Fabry disease.
Evaluating mechanisms of postoperative delirium and cognitive dysfunction following elective spine surgery in elderly patients (CONFESS): study protocol for a prospective observational trial
Authors: Müller Jonas , Nowak Stephan , Dewey Maria , Vogelgesang Antje , von Sarnowski Bettina , Rathmann Eiko , Schmidt Sein , Rehberg Sebastian , Usichenko Taras , Kertscho Harry , Hahnenkamp Klaus , Flöel Agnes , Schroeder Henry W.S. , Müller Jan-Uwe , Fleischmann Robert
Published: November 2018

Background
Elderly people are a rapidly growing proportion of the world's population that increasingly undergo major elective spine surgery. They are yet at particular high risk for postoperative delirium (POD), which is associated with longer hospital stays, higher costs, risk for delayed complications, long-term care dependency and cognitive dysfunction (POCD). It is insufficiently understood, which mechanisms and, particularly modifiable, risk factors contribute to the development of POD and POCD following these major but plannable surgeries. A better understanding thereof would help to adapt medical management and surgical strategies to individual risk profiles.
Methods
This is a single-center observational study that is jointly conducted by the departments of Neurosurgery, Neurology and Anesthesiology at a tertiary care hospital in Germany. All patients presenting to the neurosurgery outpatient clinic or ward for elective spine surgery are screened for eligibility. Inclusion criteria are age ≥ 60 years, indication for elective spine surgery, ability to give informed consent without assistance and speaking German natively. Exclusion criteria include presence of neurodegenerative disease, diagnosis of any psychiatric disease, medication with central nervous system activity (e.g. antidepressants, antipsychotics, sedatives), impossibility to participate in follow-up, participation in an interventional trial, presence of electronic or displaceable metallic implants and active neoplasm. All patients are evaluated for their preoperative cognitive abilities and physical, mental and social health and wellbeing. They additionally receive preoperative cerebrovascular ultrasound and structural and functional brain imaging. The immediate postoperative period includes screening for POD and the investigation of markers of (neuro‑)inflammation. Preoperative examinations are repeated three months postoperatively to investigate the presence of POCD and its mechanisms.
Discussion
This is the first study to prospectively evaluate risk factors for POD and POCD in spine surgery including comprehensive pre- and postoperative assessments of cognitive abilities, markers of (neuro‑)inflammation, cerebral vasculature and structural and functional neuroimaging. The identification of, possibly common, mechanisms underlying POD and POCD would be a major step towards the definition of effective interventional strategies early in or even before the postoperative period, including the adaptation of surgical strategies to individual risk profiles.
Cerebral Oxygen Desaturation in Patients with Totally Thoracoscopic Ablation for Atrial Fibrillation
Authors: Li Guohui , Shen Sai’e , Yang Liqiao , Sun Yuan , Shi Xueyin
Published: November 2018

Background: Epicardial radiofrequency ablation for atrial fibrillation under total video-assisted thoracoscopy causes severe cardiopulmonary disturbances and affects cerebral perfusion and oxygenation. The aim of the present study was to investigate the changes in regional cerebral oxygen saturation (rSO2) during the surgery and their correlations with hemodynamic or blood gas parameters.
Methods: A total of 45 patients scheduled for selective totally thoracoscopic ablation for stand-alone atrial fibrillation were enrolled in this study. The rSO2 was monitored at baseline (T0), 15 min after anesthesia induction (T1), 15 min after one-lung ventilation (T2), after right pulmonary vein ablation (T3), after left pulmonary vein ablation (T4) and 15 min after two-lung ventilation (T5) using a near-infrared reflectance spectroscopy (NIRS)-based cerebral oximeter. A Swan-Ganz catheter was placed in the pulmonary artery to obtain hemodynamic parameters. Arterial blood gas was analyzed using an ABL 825 hemoximeter. Associations between changes in rSO2 (△rSO2) and hemodynamic or blood gas parameters were determined with univariate and multivariate linear regression analyses.
Results: The rSO2 decreased greatly from baseline 65.3% to 57.5% at T3 (P < 0.001). Univariate analysis showed that △rSO2 correlated significantly with △pH (r = -0.371, P = 0.012), △PaCO2 (r = -0.276, P = 0.066), △PaO2/FiO2 (r = 0.332, P = 0.026), △HR (r = 0.27, P = 0.073), △CI (r = -0.228, P = 0.132) and △PVRI/SVRI (r = -0.216, P = 0.153). Multivariate linear regression analysis further showed that △rSO2 was only influenced by △PaO2/FiO2 (β = 0.026, P = 0.025).
Conclusion: The rSO2 decreased significantly during the totally thoracoscopic ablation for atrial fibrillation. There was a correlation between rSO2 reduction and PaO2/FiO2 changes. Greater attention should be paid to cerebral oxygen desaturation during the surgery.