bluuebunny/crossref_metadata_2025 huggingface dataset:
Dual-emissive Polymer Dots for Rapid Detection of Fluoride in Pure Water and Biological Systems with Improved Reliability and Accuracy
Authors: Zhao Qiang , Zhang Chuanqi , Liu Shujuan , Liu Yahong , Zhang Kenneth Yin , Zhou Xiaobo , Jiang Jiayang , Xu Wenjuan , Yang Tianshe , Huang Wei
Published: November 2015

It is of paramount importance to develop new probes that can selectively, sensitively, accurately and rapidly detect fluoride in aqueous media and biological systems, because F- is found to be closely related to many health and environmental concerns. Herein, a dual-emissive conjugated polyelectrolyte P1 containing phosphorescent iridium(III) complex was designed and synthesized, which can form ultrasmall polymer dots (Pdots) in aqueous media. The F--responsive tert-butyldiphenylsilyl moiety was introduced into iridium(III) complex as the signaling unit for sensing F− with the quenched phosphorescence. Thus, the dual-emissive Pdots can rapidly and accurately detect F− in aqueous media and live cells as a ratiometric probe by measuring the change in the ratio of the F−-sensitive red phosphorescence from iridium(III) complex to the F−-insensitive blue fluorescence from polyfluorene. Moreover, the interaction of Pdots with F− also changes its emission lifetime and the lifetime-based detection of F− in live cells has been realized through photoluminescence lifetime imaging microscopy for the first time. Both the ratiometric luminescence and lifetime imaging have been demonstrated to be resistant to external influences, such as the probe’s concentration and excitation power. This study provides a new perspective for the design of promising Pdots-based probes for biological applications.
Doubly curved nanofiber-reinforced optically transparent composites
Authors: Shams Md. Iftekhar , Yano Hiroyuki
Published: November 2015

Doubly curved nanofiber-reinforced optically transparent composites with low thermal expansion of 15 ppm/k are prepared by hot pressing vacuum-filtered Pickering emulsions of hydrophobic acrylic resin monomer, hydrophilic chitin nanofibers and water. The coalescence of acrylic monomer droplets in the emulsion is prevented by the chitin nanofibers network. This transparent composite has 3D shape moldability, making it attractive for optical precision parts.
A comprehensive analysis of the chorion locus in silkmoth
Authors: Chen Zhiwei , Nohata Junko , Guo Huizhen , Li Shenglong , Liu Jianqiu , Guo Youbing , Yamamoto Kimiko , Kadono-Okuda Keiko , Liu Chun , Arunkumar Kallare P. , Nagaraju Javaregowda , Zhang Yan , Liu Shiping , Labropoulou Vassiliki , Swevers Luc , Tsitoura Panagiota , Iatrou Kostas , Gopinathan Karumathil P. , Goldsmith Marian R. , Xia Qingyou , Mita Kazuei
Published: November 2015

Despite more than 40 years of intense study, essential features of the silkmoth chorion (eggshell) are still not fully understood. To determine the precise structure of the chorion locus, we performed extensive EST analysis, constructed a bacterial artificial chromosome (BAC) contig and obtained a continuous genomic sequence of 871,711 base pairs. We annotated 127 chorion genes in two segments interrupted by a 164 kb region with 5 non-chorion genes, orthologs of which were on chorion bearing scaffolds in 4 ditrysian families. Detailed transcriptome analysis revealed expression throughout choriogenesis of most chorion genes originally categorized as “middle” and evidence for diverse regulatory mechanisms including cis-elements, alternative splicing and promoter utilization and antisense RNA. Phylogenetic analysis revealed multigene family associations and faster evolution of early chorion genes and transcriptionally active pseudogenes. Proteomics analysis identified 99 chorion proteins in the eggshell and micropyle localization of 1 early and 6 Hc chorion proteins.
ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis
Authors: Chiu Kuo-Liang , Kuo Ting-Ting , Kuok Qian-Yu , Lin Yu-Sen , Hua Chung-Hung , Lin Chen-Yuan , Su Pei-Yuan , Lai Liang-Chuan , Sher Yuh-Pyng
Published: November 2015

Metastasis is the leading cause of death in cancer patients due to the difficulty of controlling this complex process. MicroRNAs (miRNA), endogenous noncoding short RNAs with important biological and pathological functions, may play a regulatory role during cancer metastasis, but this role has yet to be fully defined. We previously demonstrated that ADAM9 enhanced the expression of the pro-migratory protein CDCP1 to promote lung metastasis; however, the regulatory process remains unknown. Here we demonstrate that endogenous miR-218, which is abundant in normal lung tissue but suppressed in lung tumors, is regulated during the process of ADAM9-mediated CDCP1 expression. Suppression of miR-218 was associated with high migration ability in lung cancer cells. Direct interaction between miR-218 and the 3′-UTR of CDCP1 mRNAs was detected in luciferase-based transcription reporter assays. CDCP1 protein levels decreased as expression levels of miR-218 increased and increased in cells treated with miR-218 antagomirs. Induction of miR-218 inhibited tumor cell mobility, anchorage-free survival and tumor-initiating cell formation in vitro and delayed tumor metastases in mice. Our findings revealed an integrative tumor suppressor function of miR-218 in lung carcinogenesis and metastasis.
Early maternal loss affects social integration of chimpanzees throughout their lifetime
Authors: Kalcher-Sommersguter Elfriede , Preuschoft Signe , Franz-Schaider Cornelia , Hemelrijk Charlotte K. , Crailsheim Karl , Massen Jorg J. M.
Published: November 2015

The long-term effects of early adverse experiences on later psychosocial functioning are well described in humans, but sparsely documented for chimpanzees. In our earlier studies, we investigated the effects of maternal and social deprivation on three groups of ex-laboratory chimpanzees who experienced either an early or later onset of long-term deprivation. Here we expand our research by adding data on subjects that came from two stable zoo groups. The groups comprised of early maternally deprived wild-caught chimpanzees and non-deprived zoo-born chimpanzees. We found that compared to zoo chimpanzees, ex-laboratory chimpanzees were more restricted regarding their association partners in the newly formed groups, but not during their second year of group-life, indicating that social stability has an important influence on the toleration of association partners close-by. Social grooming activity, however, was impaired in early long-term deprived ex-laboratory chimpanzees as well as in early maternally deprived zoo chimpanzees compared to non-deprived zoo chimpanzees. Thus, we conclude that early maternal loss has lifelong effects on the social integration of chimpanzees which becomes evident in their grooming networks. Although the retrospective nature of our study prevents a clear causal explanation, our results are of importance for understanding the development of social competence in chimpanzees.
A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty
Authors: Dixon David , Coates Jonathon , del Carpio Pons Alicia , Horabin Joanna , Walker Andrew , Abdul Nicole , Kalson Nicholas S. , Brewster Nigel T. , Weir David J. , Deehan David J. , Mann Derek A. , Borthwick Lee A.
Published: November 2015

Arthrofibrosis is a fibroproliferative disease characterised by excessive deposition of extracellular matrix components intra-articularly leading to pain and restricted range of movement. Although frequently observed following total knee arthroplasty (TKA) no therapeutic options exist. A pilot study demonstrated that intra-articular injection of Anakinra, an IL-1R antagonist, improved range of movement and pain in patients with arthrofibrosis however the mechanism of action is unknown. We hypothesise that IL-1α/β will drive an inflammatory phenotype in fibroblasts isolated from the knee, therefore identifying a potential mechanism of action for Anakinra in arthrofibrosis following TKA. Fibroblasts isolated from synovial membranes and infra-patellar fat pad of patients undergoing TKA express high levels of IL-1R1. Stimulation with IL-1α/β induced a pro-inflammatory phenotype characterised by increased secretion of GMCSF, IL-6 and IL-8. No significant difference in the inflammatory response was observed between fibroblasts isolated from synovial membrane or infra-patellar fat pad. IL-1α/β treatments induced a pro-inflammatory phenotype in fibroblasts from both synovial membrane and infra-patellar fat pad and therefore Anakinra can likely have an inhibitory effect on fibroblasts present in both tissues in vivo. It is also likely that fibroblast responses in the tissues are controlled by IL-1α/β availability and not their ability to respond to it.
A mineralogical study in contrasts: highly mineralized whale rostrum and human enamel
Authors: Li Zhen , AI-Jawad Maisoon , Siddiqui Samera , Pasteris Jill D.
Published: November 2015

The outermost enamel of the human tooth and the rostrum of the whale Mesoplodon densirostris are two highly mineralized tissues that contain over 95 wt.% mineral, i.e., bioapatite. However, the same mineral type (carbonated hydroxylapatite) does not yield the same material properties, as revealed by Raman spectroscopy, scanning electron microscopy, electron microprobe analysis and synchrotron X-ray diffraction analysis. Overall, the outermost enamel of a tooth has more homogeneous physical and chemical features than the rostrum. Chemical comparison of rostrum and enamel shows bioapatite in the rostrum to be enriched in Na, Mg, CO3 and S, whereas the outermost enamel shows only a slightly enriched Cl concentration. Morphologically, mineral rods (at tens of μm scale), crystallites and prisms (at μm and sub-μm scale) and platelets (at tens of nm scale) all demonstrate less organized texture in the rostrum than in enamel. Such contrasts between two mineralized tissues suggest distinct pathways of biomineralization, e.g., the nature of the equilibrium between mineral and body fluid. This study illustrates the remarkable flexibility of the apatite mineral structure to match its chemical and physical properties to specific biological needs within the same animal or between species.
Near-infrared (NIR) up-conversion optogenetics
Authors: Hososhima Shoko , Yuasa Hideya , Ishizuka Toru , Hoque Mohammad Razuanul , Yamashita Takayuki , Yamanaka Akihiro , Sugano Eriko , Tomita Hiroshi , Yawo Hiromu
Published: November 2015

Non-invasive remote control technologies designed to manipulate neural functions have been long-awaited for the comprehensive and quantitative understanding of neuronal network in the brain as well as for the therapy of neurological disorders. Recently, it has become possible for the neuronal activity to be optically manipulated using biological photo-reactive molecules such as channelrhodopsin (ChR)-2. However, ChR2 and its relatives are mostly reactive to visible light, which does not effectively penetrate through biological tissues. In contrast, near-infrared (NIR) light (650–1450 nm) penetrates deep into the tissues because biological systems are almost transparent to light within this so-called ‘imaging window’. Here we used lanthanide nanoparticles (LNPs), composed of rare-earth elements, as luminous bodies to activate ChRs since they absorb low-energy NIR light to emit high-energy visible light (up-conversion). Here, we created a new type of optogenetic system which consists of the donor LNPs and the acceptor ChRs. The NIR laser irradiation emitted visible light from LNPs, then induced the photo-reactive responses in the near-by cells that expressed ChRs. However, there remains room for large improvements in the energy efficiency of the LNP-ChR system.
Testing for Basins of Wada
Authors: Daza Alvar , Wagemakers Alexandre , Sanjuán Miguel A. F. , Yorke James A.
Published: November 2015

Nonlinear systems often give rise to fractal boundaries in phase space, hindering predictability. When a single boundary separates three or more different basins of attraction, we say that the set of basins has theWada property and initial conditions near that boundary are even more unpredictable. Many physical systems of interest with this topological property appear in the literature. However, so far the only approach to study Wada basins has been restricted to two-dimensional phase spaces. Here we report a simple algorithm whose purpose is to look for the Wada property in a given dynamical system. Another benefit of this procedure is the possibility to classify and study intermediate situations known as partially Wada boundaries.
Production and characterization of diphenyl ditelluride-loaded nanocapsules: validation using an analytical method
Authors: Silva F. D. , Ianiski F. R. , Luchese C. , Neto J. S. S. , Zeni G. , Laporta L. V. , Rubim A. M. , Hoelzel S. C. S. M.
Published: November 2015

Organotellurium compounds are important antioxidants but toxic, therefore nanocarriers can be used to reduce toxicity.
Conformational switching of G-quadruplexes as a label-free platform for the fluorescence detection of Ag+ and biothiols
Authors: Yang Xiaoli , Wei Wei , Jiang Jianhui , Shen Guoli , Yu Ruqin
Published: November 2015

A novel label-free, sensitive and selective biosensor for the detection of Ag+ and biothiols based on the conformational switching of G-quadruplexes has been developed.
Metal–organic framework derived hollow polyhedron metal oxide posited graphene oxide for energy storage applications
Authors: Ramaraju Bendi , Li Cheng-Hung , Prakash Sengodu , Chen Chia-Chun
Published: November 2015

Cuox–rGO composite was synthesized by sintering a Cu-based metal–organic framework (Cu-MOF) embedded with exfoliated graphene oxide. The obtained material delivers an excellent electrochemical properties with stable cycling performance as an anode material in rechargeable batteries.
Surface ligand-directed pair-wise hydrogenation for heterogeneous phase hyperpolarization
Authors: Glöggler S. , Grunfeld A. M. , Ertas Y. N. , McCormick J. , Wagner S. , Bouchard L.-S.
Published: November 2015

Platinum nanoparticles capped with cysteine ligands were synthesized and utilized to create the highest polarization reported to date for heterogeneous PHIP in water.
A series of Zn(ii) and Cd(ii) coordination compounds based on 4-(4H-1,2,4-triazol-4-yl)benzoic acid: synthesis, structure and photoluminescence properties
Authors: Yang Li-Bo , Wang Hong-Can , Fang Xiao-Dan , Chen Si-Jin , Xu Quan-Qing , Zhu Ai-Xin , Yang Zhi
Published: November 2015

Seven d10 coordination compounds based on a triazolate–carboxylate bifunctional ligand have been synthesized and structurally characterized. Their thermal stability and photoluminescence properties were also investigated.
Cloud condensation nucleation activities of calcium carbonate and its atmospheric ageing products
Authors: Tang M. J. , Whitehead J. , Davidson N. M. , Pope F. D. , Alfarra M. R. , McFiggans G. , Kalberer M.
Published: November 2015

Laboratory studies suggest that atmospheric heterogeneous reactions change the CCN activity of mineral dust particles.
White light emission from a two-component hybrid gel via an energy transfer process
Authors: Cao Xinhua , Lan Haichuang , Li Zhenhua , Mao Yueyuan , Chen Liming , Wu Yongquan , Yi Tao
Published: November 2015

A two-component light-harvesting organogel containing a naphthalimide-based gelator as a donor and a phosphorescent Ir(iii) complex as an acceptor was used to produce white-light-emitting organogels.
Very fast bulk Li ion diffusivity in crystalline Li1.5Al0.5Ti1.5(PO4)3as seen using NMR relaxometry
Authors: Epp Viktor , Ma Qianli , Hammer Eva-Maria , Tietz Frank , Wilkening Martin
Published: November 2015

7Li NMR spin-lock relaxometry reveals the elementary activation barriers,EA, the ions have to jump over in LATP-based fast lithium-ion conductors.
Manganese coordination chemistry of bis(imino)phenoxide derived [2 + 2] Schiff-base macrocyclic ligands
Authors: Yang Wenxue , Zhao Ke-Qing , Wang Bi-Qin , Redshaw Carl , Elsegood Mark R. J. , Zhao Jiang-Lin , Yamato Takehiko
Published: November 2015

Products resulting from the reaction of MnCl2 with [2 + 2] Schiff-base macrocycles have been structurally characterized, and were found to be poorly active for the ROP of ε-caprolactone.
Ligand-free Pd catalyzed cross-coupling reactions in an aqueous hydrotropic medium
Authors: Jadhav Sanjay N. , Kumbhar Arjun S. , Rode Chadrashekhar V. , Salunkhe Rajashri S.
Published: November 2015

A simple, efficient and ligand-free protocol for the Suzuki–Miyaura reaction and base-free Heck–Matsuda reactions under mild reaction conditions has been developed over palladium supported on activated carbon (Pd/C) in an aqueous hydrotropic solution.
A microfluidic dual gradient generator for conducting cell-based drug combination assays
Authors: Kilinc Devrim , Schwab Jefrem , Rampini Stefano , Ikpekha Oshoke W. , Thampi Ashwin , Blasiak Agata , Li Peng , Schwamborn Robert , Kolch Walter , Matallanas David , Lee Gil U.
Published: November 2015

We present a microfluidic gradient generator that exposes cultured cells to orthogonally-aligned linear concentration gradients of two molecules. Live-cell assays quantifying apoptotic signaling and cell motility are provided as proof-of-concept.
Analysis of high-precision vanadium isotope ratios by medium resolution MC-ICP-MS
Authors: Nielsen Sune G. , Owens Jeremy D. , Horner Tristan J.
Published: November 2015

We present and verify a new method to measure vanadium isotope ratios using a Thermo Scientific Neptune multi-collector inductively-coupled plasma mass spectrometer (MC-ICP-MS) operated in medium mass resolution mode.
Synthesis, and antitubercular and antimicrobial activity of 1′-(4-chlorophenyl)pyrazole containing 3,5-disubstituted pyrazoline derivatives
Authors: Harikrishna N. , Isloor Arun M. , Ananda K. , Obaid Abdulrahman , Fun Hoong-Kun
Published: November 2015

A new series of pyrazoline derivatives was synthesized and characterized using spectral techniques. The synthesized compounds were evaluated for their antitubercular and antimicrobial activities. Most of the compounds are found to be biologically potent.
Rod-in-tube nanostructure of MgFe2O4: electrospinning synthesis and photocatalytic activities of tetracycline
Authors: Jiang Jinhui , Fan Weiqiang , Zhang Xian , Bai Hongye , Liu Yu , Huang Shuai , Mao Baodong , Yuan Songliu , Liu Chunbo , Shi Weidong
Published: November 2015

The special structure of MgFe2O4 has better photocatalytic performance and better stability.
Preparation of porous alumina microspheres via an oil-in-water emulsion method accompanied by a sol–gel process
Authors: Yang Hui , Xie Yuan , Hao Guisong , Cai Weiwei , Guo Xingzhong
Published: November 2015

Porous alumina microspheres prepared via a facile template-free approach followed by heat-treatment, exhibiting a three-dimensional interconnected structure.
Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology
Authors: Weissman Kira J.
Published: November 2015

This reviews covers on-going efforts at engineering the gigantic modular polyketide synthases (PKSs), highlighting both notable successes and failures.
Modulating single-molecule magnet behaviour of phenoxo-O bridged lanthanide(iii) dinuclear complexes by using different β-diketonate coligands
Authors: Wang Wen-Min , Wang Shi-Yu , Zhang Hong-Xia , Shen Hai-Yun , Zou Ji-Yong , Gao Hong-Ling , Cui Jian-Zhong , Zhao Bin
Published: November 2015

Three Dy2 complexes with similar crystal structure have been synthesized. Magnetic studies reveal that they exhibit different magnetic relaxation behaviors, originating from the different chemical environments of the center Dy3+ ions with different β-diketonate coligands.
CO2 sensing properties of La1−xBaxFeO3 thick film and packed powder sensors
Authors: Li Ling , Qin Hongwei , Shi Changmin , Zhang Ling , Chen Yanping , Hu Jifan
Published: November 2015

We compared the CO2 sensing properties of La1−xBaxFeO3 packed powder and thick film sensors.
Biomass derived xylose Guerbet surfactants: thermotropic and lyotropic properties from small-angle X-ray scattering
Authors: Liew Chia Yen , Salim Malinda , Zahid N. Idayu , Hashim Rauzah
Published: November 2015

A series of novel branched-chain glycosides were synthesised from xylose, an aldopentose and Guerbet alcohols whose total number of carbon atoms ranges from C8–C24. Interestingly dry β-Xyl-C8C4 gave a rectangular columnar ribbon phase at 25 °C.
Lipase immobilization towards improved productivity on kinetic resolutions by a continuous-flow process
Authors: Silva Marcus V. M. , Bassut Jonathan F. , Junior Ivaldo I. , de Souza Stefania P. , Estrada Melissa L. G. , Miranda Leandro S. M. , de Souza Rodrigo O. M. A.
Published: November 2015

Development of asymmetric transformations for the synthesis of chiral molecules has achieved great results in the last decade.
Computational design of a two-photon excited FRET-based ratiometric fluorescent Cu2+ probe for living cell imaging
Authors: Wang Dan , Ren Ai-Min , Guo Jing-Fu , Zou Lu-Yi , Huang Shuang
Published: November 2015

A novel TP FRET ratiometric fluorescent probe 2a for Cu2+ is designed. 2a has a large TPA peak in the near-infrared light region and its energy transfer efficiency is nearly 100%.
Asymmetric surface effect on the configuration of bilayer Si/SiGe nanosprings
Authors: Kim Seongseop , Kim Wonbae , Chung Hayoung , Cho Maenghyo
Published: November 2015

This study investigates the asymmetric surface effect on nanosprings composed of Si/SiGe bilayer thin films.
Ionic liquid polymer functionalized carbon nanotubes-coated polyaniline for the solid-phase microextraction of benzene derivatives
Authors: Wu Mian , Wang Liying , Zhao Faqiong , Zeng Baizhao
Published: November 2015

Schematic demonstration of the preparation of PANI-PIL/MWCNTs coated fiber.
Isoindigo-based microporous organic polymers for carbon dioxide capture
Authors: Zhao Yang , Wang Xiaoyan , Zhang Chong , Xie Fangyuan , Kong Rui , Jiang Jia-Xing
Published: November 2015

Isoindigo-based microporous organic polymers show a high CO2 uptake ability of 3.30 mmol g−1 (1.13 bar/273 K) with a CO2/N2 sorption selectivity of 58.8 : 1.
Synthesis of g-C3N4 at different temperatures for superior visible/UV photocatalytic performance and photoelectrochemical sensing of MB solution
Authors: Mo Zhao , She Xiaojie , Li Yeping , Liu Liang , Huang Liying , Chen Zhigang , Zhang Qi , Xu Hui , Li Huaming
Published: November 2015

The visible light absorption of g-C3N4 was extended through controlling the synthesis temperature, and thus enhanced visible/UV photocatalytic activity. Moreover, g-C3N4 can also be used as a photoelectrochemical sensor.
Biogenic gold nanoparticles-reduced graphene oxide nanohybrid: synthesis, characterization and application in chemical and biological reduction of nitroaromatics
Authors: Dong Bin , Liu Guangfei , Zhou Jiti , Wang Aijie , Wang Jing , Jin Ruofei , Lv Hong
Published: November 2015

The biogenic AuNPs/rGO can participate in and accelerate electron transfer, and catalyze both chemical and biological reduction of nitroaromatics efficiently.
Enhanced visible light photocatalytic activity of polyaniline–crystalline TiO2–halloysite composite nanotubes by tuning the acid dopant in the preparation
Authors: Li Cuiping , Zhou Tianzhu , Zhu Tianwen , Li Xueyuan
Published: November 2015

One-dimensional heterogeneous polyaniline–crystalline TiO2–halloysite nanotubes with enhanced visible-light photocatalytic activity were achieved by tuning the acid dopant in the preparation at low temperature.
Facile synthesis of nanostructured LiMnPO4 as a high-performance cathode material with long cycle life and superior rate capability
Authors: Liao Longhuan , Xie Jian , Zhang Shichao , Cao Gaoshao , Zhao Xinbing
Published: November 2015

Nano-LiMnPO4/C exhibits superior rate capability and long cycling stability, sustaining stable cycling over 500 cycles at 10C.
Microfluidic synthesis of ultra-small magnetic nanohybrids for enhanced magnetic resonance imaging
Authors: Wang Junmei , Zhao Kai , Shen Xiaomiao , Zhang Weiwei , Ji Shaoxia , Song Yujun , Zhang Xiaodong , Rong Rong , Wang Xiaoying
Published: November 2015

We have developed a core alloying and shell gradient doping strategy for the controlled surface modification of Fe or CoFe nanoparticles for enhanced magnetic resonance imaging.
Organic semiconductors with a charge carrier life time of over 2 hours at room temperature
Authors: Liu Yang , MacKenzie Roderick. C. I. , Xu Bin , Gao Yajun , Gimeno-Fabra Miquel , Grant David , van Loosdrecht Paul. H. M. , Tian Wenjing
Published: November 2015

By tuning both the materials used in the device, and it's structure we are able to observe a charge carrier life time of over 2 hours and still extract significant amounts of charge after 5 hours.
Production of Korean Idiomatic Utterances Following Left- and Right-Hemisphere Damage: Acoustic Studies
Authors: Yang Seung-yun , Van Lancker Sidtis Diana
Published: November 2015

Purpose

This study investigates the effects of left- and right-hemisphere damage (LHD and RHD) on the production of idiomatic or literal expressions utilizing acoustic analyses.

Method

Twenty-one native speakers of Korean with LHD or RHD and in a healthy control (HC) group produced 6 ditropically ambiguous (idiomatic or literal) sentences in 2 different speech tasks: elicitation and repetition. Utterances were analyzed using durational and fundamental-frequency (F0) measures. Listeners' goodness ratings (how well each utterance represented its category: idiomatic or literal) were correlated with acoustic measures.

Results

During the elicitation tasks, the LHD group differed significantly from the HC group in durational measures. Significant differences between the RHD and HC groups were seen in F0 measures. However, for the repetition tasks, the LHD and RHD groups produced utterances comparable to the HC group's performance. Using regression analysis, selected F0 cues were found to be significant predictors for goodness ratings by listeners.

Conclusions

Using elicitation, speakers in the LHD group were deficient in producing durational cues, whereas RHD negatively affected the production of F0 cues. Performance differed for elicitation and repetition, indicating a task effect. Listeners' goodness ratings were highly correlated with the production of certain acoustic cues. Both the acoustic and functional hypotheses of hemispheric specialization were supported for idiom production.
Comparison of Intelligibility Measures for Adults With Parkinson's Disease, Adults With Multiple Sclerosis, and Healthy Controls
Authors: Stipancic Kaila L. , Tjaden Kris , Wilding Gregory
Published: November 2015

Purpose

This study obtained judgments of sentence intelligibility using orthographic transcription for comparison with previously reported intelligibility judgments obtained using a visual analog scale (VAS) for individuals with Parkinson's disease and multiple sclerosis and healthy controls (K. Tjaden, J. E. Sussman, & G. E. Wilding, 2014).

Method

Speakers read Harvard sentences in habitual, clear, loud, and slow conditions. Sentence stimuli were equated for peak intensity and mixed with multitalker babble. A total of 50 listeners orthographically transcribed sentences. Procedures were identical to those for a VAS reported in Tjaden, Sussman, and Wilding (2014).

Results

The percent correct scores from transcription were significantly higher in magnitude than the VAS scores. Multivariate linear modeling indicated that the pattern of findings for transcription and VAS was virtually the same with respect to differences among groups and speaking conditions. Correlation analyses further indicated a moderately strong, positive relationship between the two metrics. The majority of these correlations were significant. Last, intrajudge and interjudge listener reliability metrics for the two intelligibility tasks were comparable.

Conclusion

Results suggest that there may be instances when the less time-consuming VAS task may be a viable substitute for an orthographic transcription task when documenting intelligibility in mild dysarthria.
Resistive switching mechanism in printed non‐volatile Ag/ZrO2/ITO sandwiched structure
Authors: Awais M.N. , Choi K.H.
Published: November 2015

The resistive switching mechanism in the printed sandwiched structures of Ag/zirconium oxide/indium tin oxide (ITO) is analytically demonstrated. The switching from the ON to OFF state of the fabricated device is attributed to the modulation of ohmic contact into opposite Schottky barriers following on from the electrochemical dissolution of the Ag filament from the weakest point near the ITO electrode and alteration of the Schottky barriers into an ohmic contact consequential to the reformation of the Ag filament during the transition of OFF into ON state. Physical current conduction governing laws verify the concluded transitions between ohmic contact and Schottky barriers.
Clustering‐based interference management in dense small cell networks with backhaul constraints
Authors: Liu Jinbo , Sun Shaohui , Liu Jiamin , He Yuan
Published: November 2015

Small cell has been considered as a promising solution since it can improve coverage and system throughput. When a large number of small cells are overlapped, the limited backhaul capacity of the small cell and serious inter‐cell interference become one of the major technical challenges. A clustering‐based interference mitigation for dense small cell networks with backhaul constraints is investigated. The optimal problem which maximises the system capacity has been formulated. No‐inter cluster and graph‐based cluster are proposed, so as to reduce the inter‐cell interference. Taking into account the chemical reaction optimisation and backhaul constraints, more interference could be mitigated and guarantee the limited backhaul. The simulation results demonstrate that the proposed policy could enhance the system throughput.
Internal electric field in pregnant‐woman model for wireless power transfer systems in electric vehicles
Authors: Shimamoto T. , Laakso I. , Hirata A.
Published: November 2015

One of the limiting factors for transmitting power in the wireless power transfer system for electric vehicles is the human safety compliance requirement for magnetic field leakage. Another concern for human safety from electromagnetic fields is the impact on vulnerable populations, such as the foetus and its mother. In this study, the internal electric field in the foetus and mother is investigated in anatomically based pregnant‐ and non‐pregnant‐woman models. The effect of different coil designs on the internal electric field is also discussed. The computational results show that the internal electric field strength is smaller in the foetus than in the mother, because the magnetic field there is weaker than around the feet, even though the abdomen of the pregnant woman may come closer to the vehicle than that of a non‐pregnant adult female. The allowable transmitting power for safety compliance is of the order of megawatts, which is a magnitude higher than that considered in the standardisation.
Detailed simulation of electrical demands due to nationwide adoption of heat pumps, taking account of renewable generation and mitigation
Authors: Cooper Samuel J.G. , Hammond Geoffrey P. , McManus Marcelle C. , Pudjianto Danny
Published: November 2015

This study quantifies the increase in the peak power demand, net of non‐dispatchable generation, that may be required by widespread adoption of heat pumps. Electrification of heating could reduce emissions but also cause a challenging increase in peak power demand. This study expands on previous studies by quantifying the increase in greater detail; considering a wider range of scenarios, the characteristics of heat pumps and the interaction between wind generation and demand side management (DSM). A model was developed with dynamic simulations of individual heat pumps and dwellings. The increase in peak net‐demand is highly sensitive to assumptions regarding the heat pumps, their installation, building fabric and the characteristics of the grid. If 80% of dwellings in the UK use heat pumps, peak net‐demand could increase by around 100% (54 GW) but this increase could be mitigated to 30% (16 GW) by favourable conditions. DSM could reduce this increase to 20%, or 15% if used with extensive thermal storage. If 60% of dwellings use heat pumps, the increase in peak net‐demand could be as low as 5.5 GW. High‐performance heat pumps, appropriate installation and better insulated dwellings could make the increase in peak net‐demand due to the electrification of heating more manageable.
Living On; Not Getting Better
Authors: Shildrick Margrit
Published: November 2015

The contemporary emergence of the concept ‘debility’, which pertains to a broad swathe of humanity whose ordinary lives simply persist without ever getting better, shares a time span with an acute critique of neo-liberal biopolitics. Where capital has historically relied on a population that through its labour necessarily becomes debilitated, the newer model of understanding references the intrinsic profitability of debility itself. The two dimensions overlap and co-exist, but what I shall pursue here are the implications of recognising that, at the most fundamental level, it is in the interests of neo-liberalism to produce and sustain bodies as debilitated and therefore susceptible to a range of market commodities that hold out the promise of therapeutic interventions into the relative failures of physical, cognitive and affective embodiment. In previous work, I have argued strongly for the inherent vulnerability of all bodies, but in considering here a more overtly politicised context, it becomes possible to readdress the questions posed by Jasbir Puar: ‘which bodies are made to pay for “progress”? Which debilitated bodies can be reinvigorated for neoliberalism, and which cannot?’ And at the present moment, writing at a time of imposed austerity, I would add, what, if anything, is lost in the deployment of the term debility instead of disability?
An ultra-thin broadband active frequency selective surface absorber for ultrahigh-frequency applications
Authors: Xu Wenhua , He Yun , Kong Peng , Li Jialin , Xu Haibing , Miao Ling , Bie Shaowei , Jiang Jianjun
Published: November 2015

At frequencies below 2 GHz, conventional microwave absorbers are limited in application by their thickness or narrow absorption bandwidth. In this paper, we propose and fabricate an ultra-thin broadband active frequency selective surface (AFSS) absorber with a stretching transformation (ST) pattern for use in the ultrahigh-frequency (UHF) band. This absorber is loaded with resistors and varactors to produce its tunability. To expand the tunable bandwidth, we applied the ST with various coefficients x and y to the unit cell pattern. With ST coefficients of x = y = 1, the tunability and strong absorption are concisely demonstrated, based on a discussion of impedance matching. On analyzing the patterns with various ST coefficients, we found that a small x/y effectively expands the tunable bandwidth. After this analysis, we fabricated an AFSS absorber with ST coefficients of x = 0.7 and y = 1. Its measured reflectivity covered a broad band of 0.7–1.9 GHz below −10 dB at bias voltages of 10–48 V. The total thickness of this absorber, 7.8 mm, was only ∼λ/54 of the lower limit frequency, ∼λ/29 of the center frequency, and ∼λ/20 of the higher limit frequency. Our measurements and simulated results indicate that this AFSS absorber can be thin and achieve a broad bandwidth simultaneously.
Selective wet-etch processing of optically transparent flexible InGaZnO thin-film transistors
Authors: Tari Alireza , Wong William S.
Published: November 2015

Flexible InGaZnO (IGZO) thin-film transistors (TFTs) having more than 85% optical transparency in the visible regime were fabricated on polyethylene naphthalate substrates using a selective wet etching process at a maximum temperature of 150 °C. An etch selectivity of >15 was used to pattern Al-doped ZnO S/D contacts on IGZO channel layers in a back-channel etch process. Flexible IGZO TFTs exhibited a field-effect mobility of ∼9.5 cm2/V s, threshold voltage of ∼4 V, subthreshold swing of 0.5 V/decade, and an Ion/Ioff ratio of ∼107. Similar I-V characteristics were measured for flexible TFTs under flat, tensile and compressive strain while a 3.8 V threshold voltage shift was observed after application of a dc gate-bias for 3600 s with the TFTs operating in the linear regime.
Transferred large area single crystal MoS2 field effect transistors
Authors: Lee Choong Hee , McCulloch William , Lee Edwin W. , Ma Lu , Krishnamoorthy Sriram , Hwang Jinwoo , Wu Yiying , Rajan Siddharth
Published: November 2015

Transfer of epitaxial, two-dimensional (2D) MoS2 on sapphire grown via synthetic approaches is a prerequisite for practical device applications. We report centimeter-scale, single crystal, synthesized MoS2 field effect transistors (FETs) transferred onto SiO2/Si substrates, with a field-effect mobility of 4.5 cm2 V−1 s−1, which is among the highest mobility values reported for the transferred large-area MoS2 transistors. We demonstrate simple and clean transfer of large-area MoS2 films using deionized water, which can effectively avoid chemical contamination. The transfer method reported here allows standard i-line stepper lithography process to realize multiple devices over the entire film area.
Tracer diffusion of hard-sphere binary mixtures under nano-confinement
Authors: Marini Bettolo Marconi Umberto , Malgaretti Paolo , Pagonabarraga Ignacio
Published: November 2015

The physics of diffusion phenomena in nano- and microchannels has attracted a lot of attention in recent years, due to its close connection with many technological, medical, and industrial applications. In the present paper, we employ a kinetic approach to investigate how the confinement in nanostructured geometries affects the diffusive properties of fluid mixtures and leads to the appearance of properties different from those of bulk systems. In particular, we derive an expression for the friction tensor in the case of a bulk fluid mixture confined to a narrow slit having undulated walls. The boundary roughness leads to a new mechanism for transverse diffusion and can even lead to an effective diffusion along the channel larger than the one corresponding to a planar channel of equivalent section. Finally, we discuss a reduction of the previous equation to a one dimensional effective diffusion equation in which an entropic term encapsulates the geometrical information on the channel shape.
Dispersion characteristics of spin-electromagnetic waves in planar multiferroic structures
Authors: Nikitin Andrey A. , Ustinov Alexey B. , Vitko Vitaliy V. , Semenov Alexander A. , Belyavskiy Pavel Yu. , Mironenko Igor G. , Stashkevich Andrey A. , Kalinikos Boris A. , Lähderanta E.
Published: November 2015

A method of approximate boundary conditions is used to derive dispersion relations for spin-electromagnetic waves (SEWs) propagating in thin ferrite films and in multiferroic layered structures. A high accuracy of this method is proven. It was shown that the spin-electromagnetic wave propagating in the structure composed of a thin ferrite film, a thin ferroelectric film, and a slot transmission line is formed as a result of hybridization of the surface spin wave in the ferrite film and the electromagnetic wave in the slot-line. The structure demonstrates dual electric and magnetic field tunability of the SEW spectrum. The electric field tunability is provided by the thin ferroelectric film. Its efficiency increases with an increase in the thicknesses of the ferrite and ferroelectric films and with a decrease in the slot-line gap width. The theory is confirmed by experimental data.
Implementing Indigenous community control in health care: lessons from Canada
Authors: Lavoie Josée G. , Dwyer Judith
Published: November 2015

Objective
Over past decades, Australian and Canadian Indigenous primary healthcare policies have focused on supporting community controlled Indigenous health organisations. After more than 20 years of sustained effort, over 89% of eligible communities in Canada are currently engaged in the planning, management and provision of community controlled health services. In Australia, policy commitment to community control has also been in place for more than 25 years, but implementation has been complicated by unrealistic timelines, underdeveloped change management processes, inflexible funding agreements and distrust. This paper discusses the lessons from the Canadian experience to inform the continuing efforts to achieve the implementation of community control in Australia.

Methods
We reviewed Canadian policy and evaluation grey literature documents, and assessed lessons and recommendations for relevance to the Australian context.

Results
Our analysis yielded three broad lessons. First, implementing community control takes time. It took Canada 20 years to achieve 89% implementation. To succeed, Australia will need to make a firm long term commitment to this objective. Second, implementing community control is complex. Communities require adequate resources to support change management. And third, accountability frameworks must be tailored to the Indigenous primary health care context to be meaningful.

Conclusions
We conclude that although the Canadian experience is based on a different context, the processes and tools created to implement community control in Canada can help inform the Australian context.

What is known about the topic?
Although Australia has promoted Indigenous control over primary healthcare (PHC) services, implementation remains incomplete. Enduring barriers to the transfer of PHC services to community control have not been addressed in the largely sporadic attention to this challenge to date, despite significant recent efforts in some jurisdictions.

What does this paper add?
The Canadian experience indicates that transferring PHC from government to community ownership requires sustained commitment, adequate resourcing of the change process and the development of a meaningful accountability framework tailored to the sector.

What are the implications for practitioners?
Policy makers in Australia will need to attend to reform in contractual arrangements (towards pooled or bundled funding), adopt a long-term vision for transfer and find ways to harmonise the roles of federal and state governments. The arrangements achieved in some communities in the Australian Coordinated Care Trials (and still in place) provide a model.
Revising upper-ocean sulfur dynamics near Bermuda: new lessons from 3 years of concentration and rate measurements
Authors: Levine Naomi M. , Toole Dierdre A. , Neeley Aimee , Bates Nicholas R. , Doney Scott C. , Dacey John W. H.
Published: November 2015

Environmental context Microscopic marine organisms have the potential to influence the global climate through the production of a trace gas, dimethylsulfide, which contributes to cloud formation. Using 3 years of observations, we investigated the environmental drivers behind the production and degradation of dimethylsulfide and its precursor dimethylsulfoniopropionate. Our results highlight the important role of the microbial community in rapidly cycling these compounds and provide an important dataset for future modelling studies. Abstract Oceanic biogeochemical cycling of dimethylsulfide (DMS), and its precursor dimethylsulfoniopropionate (DMSP), has gained considerable attention over the past three decades because of the potential role of DMS in climate mediation. Here we report 3 years of monthly vertical profiles of organic sulfur cycle concentrations (DMS, particulate DMSP (DMSPp) and dissolved DMSP (DMSPd)) and rates (DMSPd consumption, biological DMS consumption and DMS photolysis) from the Bermuda Atlantic Time-series Study (BATS) site taken between 2005 and 2008. Concentrations confirm the summer paradox with mixed layer DMS peaking ~90 days after peak DMSPp and ~50 days after peak DMSPp:Chl. A small decline in mixed layer DMS was observed relative to those measured during a previous study at BATS (1992–1994), potentially driven by long-term climate shifts at the site. On average, DMS cycling occurred on longer timescales than DMSPd (0.43±0.35 v. 1.39±0.76 day–1) with DMSPd consumption rates remaining elevated throughout the year despite significant seasonal variability in the bacterial DMSP degrader community. DMSPp was estimated to account for 4–5% of mixed layer primary production and turned over at a significantly slower rate (~0.2 day–1). Photolysis drove DMS loss in the mixed layer during the summer, whereas biological consumption of DMS was the dominant loss process in the winter and at depth. These findings offer new insight into the underlying mechanisms driving DMS(P) cycling in the oligotrophic ocean, provide an extended dataset for future model evaluation and hypothesis testing and highlight the need for a reexamination of past modelling results and conclusions drawn from data collected with old methodologies.
Stochastic games
Authors: Solan Eilon , Vieille Nicolas
Published: November 2015

In 1953, Lloyd Shapley contributed his paper “Stochastic games” to PNAS. In this paper, he defined the model of stochastic games, which were the first general dynamic model of a game to be defined, and proved that it admits a stationary equilibrium. In this Perspective, we summarize the historical context and the impact of Shapley’s contribution.
Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis
Authors: Hwang Seong-Hye , Jung Seung-Hyun , Lee Saseong , Choi Susanna , Yoo Seung-Ah , Park Ji-Hwan , Hwang Daehee , Shim Seung Cheol , Sabbagh Laurent , Kim Ki-Jo , Park Sung Hwan , Cho Chul-Soo , Kim Bong-Sung , Leng Lin , Montgomery Ruth R. , Bucala Richard , Chung Yeun-Jun , Kim Wan-Uk
Published: November 2015

Significance

We screened rheumatoid arthritis (RA)-associated copy number variations (CNVs) across the whole genome and identified significant deletion variants encompassing leukocyte-specific protein 1 (LSP1) gene. Functional assays revealed that LSP1, induced by T-cell receptor activation, negatively regulates T-cell migration. Loss ofLsp1promotes T-cell migration into antigen-instilled tissues and draining lymph nodes in mice with T-cell–dependent chronic inflammation. Moreover, patients with RA show diminished expression of LSP1 in peripheral T cells with increased migratory capacity. To our knowledge, our work is the first to demonstrate how CNVs result in immune dysfunction and a disease phenotype, highlighting the importance ofLSP1CNVs and LSP1 insufficiency in the pathogenesis of RA.
Redistribution of soil water by a saprotrophic fungus enhances carbon mineralization
Authors: Guhr Alexander , Borken Werner , Spohn Marie , Matzner Egbert
Published: November 2015

Significance

This work shows a mechanism behind the observed higher drought resistance of soil fungi compared with bacteria. It also demonstrates the relevance of hydraulic redistribution by saprotrophic fungi for ecosystem ecology by influencing the carbon and water cycle in soils and terrestrial ecosystems under drought. Furthermore, we documented a so far underrated pathway of water in desiccated soils.