bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods and Materials from RalA Function in Dermal Fibroblasts Is Required for the Progression of Squamous Cell Carcinoma of the Skin
Authors: Sowalsky Adam G. , Alt-Holland Addy , Shamis Yulia , Garlick Jonathan A. , Feig Larry A.
Published: April 2023

Supplementary Methods and Materials from RalA Function in Dermal Fibroblasts Is Required for the Progression of Squamous Cell Carcinoma of the Skin
Supplementary Figure Legends 1-5 from RalA Function in Dermal Fibroblasts Is Required for the Progression of Squamous Cell Carcinoma of the Skin
Authors: Sowalsky Adam G. , Alt-Holland Addy , Shamis Yulia , Garlick Jonathan A. , Feig Larry A.
Published: April 2023

Supplementary Figure Legends 1-5 from RalA Function in Dermal Fibroblasts Is Required for the Progression of Squamous Cell Carcinoma of the Skin
Supplementary Table 1 from Uncoupling of PI3K from ErbB3 Impairs Mammary Gland Development but Does Not Impact on ErbB2-Induced Mammary Tumorigenesis
Authors: Lahlou Hicham , Müller Thomas , Sanguin-Gendreau Virginie , Birchmeier Carmen , Muller William J.
Published: April 2023

PDF file - 54K, Progeny of ErbB3D85 breeding pairs
Supplementary Methods, Figure Legends 1-6 from Uncoupling of PI3K from ErbB3 Impairs Mammary Gland Development but Does Not Impact on ErbB2-Induced Mammary Tumorigenesis
Authors: Lahlou Hicham , Müller Thomas , Sanguin-Gendreau Virginie , Birchmeier Carmen , Muller William J.
Published: April 2023

PDF file - 106K
Supplementary Figure 4 from Select Heterozygous Keap1 Mutations Have a Dominant-Negative Effect on Wild-Type Keap1 In Vivo
Authors: Suzuki Takafumi , Maher Jonathan , Yamamoto Masayuki
Published: April 2023

Supplementary Figure 4 from Select Heterozygous Keap1 Mutations Have a Dominant-Negative Effect on Wild-Type Keap1 In Vivo
Supplementary Figure 1 from Uncoupling of PI3K from ErbB3 Impairs Mammary Gland Development but Does Not Impact on ErbB2-Induced Mammary Tumorigenesis
Authors: Lahlou Hicham , Müller Thomas , Sanguin-Gendreau Virginie , Birchmeier Carmen , Muller William J.
Published: April 2023

PDF file - 31K, SacI- and SpeI/SphI-digested genomic DNA from mice with the indicated genotypes
Supplementary Figures 1-8, Tables 1-3 from HIF-1α Confers Aggressive Malignant Traits on Human Tumor Cells Independent of Its Canonical Transcriptional Function
Authors: Yoo Young-Gun , Christensen Jared , Huang L. Eric
Published: April 2023

Supplementary Figures 1-8, Tables 1-3 from HIF-1α Confers Aggressive Malignant Traits on Human Tumor Cells Independent of Its Canonical Transcriptional Function
Supplementary Figure Legend from Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells
Authors: Faget Julien , Biota Cathy , Bachelot Thomas , Gobert Michael , Treilleux Isabelle , Goutagny Nadège , Durand Isabelle , Léon-Goddard Sophie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: April 2023

PDF file - 105KB
Supplementary Figure 3 from Noncytotoxic Differentiation Treatment of Renal Cell Cancer
Authors: Negrotto Soledad , Hu Zhenbo , Alcazar Oscar , Ng Kwok Peng , Triozzi Pierre , Lindner Daniel , Rini Brian , Saunthararajah Yogen
Published: April 2023

Supplementary Figure 3 from Noncytotoxic Differentiation Treatment of Renal Cell Cancer
Supplementary Figure 1 from Noncytotoxic Differentiation Treatment of Renal Cell Cancer
Authors: Negrotto Soledad , Hu Zhenbo , Alcazar Oscar , Ng Kwok Peng , Triozzi Pierre , Lindner Daniel , Rini Brian , Saunthararajah Yogen
Published: April 2023

Supplementary Figure 1 from Noncytotoxic Differentiation Treatment of Renal Cell Cancer
Supplementary Table 1, Figure 1 from Itraconazole Inhibits Angiogenesis and Tumor Growth in Non–Small Cell Lung Cancer
Authors: Aftab Blake T. , Dobromilskaya Irina , Liu Jun O. , Rudin Charles M.
Published: April 2023

PDF file - 145K
Supplementary Video 4 from p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior
Authors: Rosenthal Devin T. , Iyer Harish , Escudero Silvia , Bao Liwei , Wu Zhifen , Ventura Alejandra C. , Kleer Celina G. , Arruda Ellen M. , Garikipati Krishna , Merajver Sofia D.
Published: April 2023

AVI file - 546K
Supplementary Video 2 from p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior
Authors: Rosenthal Devin T. , Iyer Harish , Escudero Silvia , Bao Liwei , Wu Zhifen , Ventura Alejandra C. , Kleer Celina G. , Arruda Ellen M. , Garikipati Krishna , Merajver Sofia D.
Published: April 2023

AVI file - 2.8MB
Supplementary Table 2 from Development of a Hypoxia Gene Expression Classifier with Predictive Impact for Hypoxic Modification of Radiotherapy in Head and Neck Cancer
Authors: Toustrup Kasper , Sørensen Brita Singers , Nordsmark Marianne , Busk Morten , Wiuf Carsten , Alsner Jan , Overgaard Jens
Published: April 2023

PDF file - 51K
Supplementary Methods, Legends for Figures 1-3, Videos 1-4 from p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior
Authors: Rosenthal Devin T. , Iyer Harish , Escudero Silvia , Bao Liwei , Wu Zhifen , Ventura Alejandra C. , Kleer Celina G. , Arruda Ellen M. , Garikipati Krishna , Merajver Sofia D.
Published: April 2023

PDF file - 193K
Supplementary Figure 1B from Induction of the RNA Regulator LIN28A Is Required for the Growth and Pathogenesis of RESTless Breast Tumors
Authors: Gunsalus Kearney T.W. , Wagoner Matthew P. , Meyer Kassondra , Potter Wyatt B. , Schoenike Barry , Kim Soyoung , Alexander Caroline M. , Friedl Andreas , Roopra Avtar
Published: April 2023

PDF file - 525K, Analysis of dataset GSE2034 using the RESTless Gene Signature and clustered using Euclidean distance.
Supplementary Figure 1A from Induction of the RNA Regulator LIN28A Is Required for the Growth and Pathogenesis of RESTless Breast Tumors
Authors: Gunsalus Kearney T.W. , Wagoner Matthew P. , Meyer Kassondra , Potter Wyatt B. , Schoenike Barry , Kim Soyoung , Alexander Caroline M. , Friedl Andreas , Roopra Avtar
Published: April 2023

PDF file - 463K, Analysis of dataset GSE2990 using the RESTless Gene Signature and clustered using Euclidean distance.
Supplementary Figures 1-8 from Parkin Pathway Activation Mitigates Glioma Cell Proliferation and Predicts Patient Survival
Authors: Yeo Calvin W.S. , Ng Felicia S.L. , Chai Chou , Tan Jeanne M.M. , Koh Geraldene R.H. , Chong Yuk Kien , Koh Lynnette W.H. , Foong Charlene S.F. , Sandanaraj Edwin , Holbrook Joanna D. , Ang Beng-Ti , Takahashi Ryosuke , Tang Carol , Lim Kah-Leong
Published: April 2023

PDF file - 508K
Supplementary Video 9 from Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion
Authors: Dang Tuyen T. , Prechtl Amanda M. , Pearson Gray W.
Published: April 2023

MOV file - 50K, Live-imaging of a HCC1954-H2B:GFP spheroid used for tracking cell movement.
Supplementary Figures 1-7 from Wnt/Snail Signaling Regulates Cytochrome c Oxidase and Glucose Metabolism
Authors: Lee Su Yeon , Jeon Hyun Min , Ju Min Kyung , Kim Cho Hee , Yoon Gyesoon , Han Song Iy , Park Hye Gyeong , Kang Ho Sung
Published: April 2023

PDF file - 3.8MB, Supplemental Figures S1-S7 include the Induction of EMT in MCF-7 cells (Figure S1), the effects of Wnt on mitochondrial mass (Figure S2), Ponceau S staining corresponding to Figure 4A (Figure S3), ChIP assays using Wnt3a-treated or Snail-transfected MCF-7 cells (Figure S4), mitochondrial repression and glycolytic switch by PC shRNA (Figure S5), the effects of E-cadherin shRNA and Snail shRNA on the expression of COXVIc, COXVIIa, COXVIIc, and PC (Figure S6), and a schematic representation showing a new function of Wnt/Snail (Figure S7)
Supplementary Video 7 from Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion
Authors: Dang Tuyen T. , Prechtl Amanda M. , Pearson Gray W.
Published: April 2023

MOV file - 773K, Live-imaging of MCFDCIS-mCherryCAAX cells invading towards mammary fibroblasts expressing GFP.
Supplementary Figure 3 from Overexpression of a Novel Activator of PAK4, the CDK5 Kinase–Associated Protein CDK5RAP3, Promotes Hepatocellular Carcinoma Metastasis
Authors: Mak Grace Wing-Yan , Chan Mandy Man-Lok , Leong Veronica Yee-Law , Lee Joyce Man-Fong , Yau Tai-On , Ng Irene Oi-Lin , Ching Yick-Pang
Published: April 2023

Supplementary Figure 3 from Overexpression of a Novel Activator of PAK4, the CDK5 Kinase–Associated Protein CDK5RAP3, Promotes Hepatocellular Carcinoma Metastasis
Supplementary Video 3 from Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion
Authors: Dang Tuyen T. , Prechtl Amanda M. , Pearson Gray W.
Published: April 2023

MOV file - 105K, Live-imaging of a MCFDCIS-mCherryCAAX spheroid and a mammary fibroblast.
Supplementary Figure 2 from Overexpression of a Novel Activator of PAK4, the CDK5 Kinase–Associated Protein CDK5RAP3, Promotes Hepatocellular Carcinoma Metastasis
Authors: Mak Grace Wing-Yan , Chan Mandy Man-Lok , Leong Veronica Yee-Law , Lee Joyce Man-Fong , Yau Tai-On , Ng Irene Oi-Lin , Ching Yick-Pang
Published: April 2023

Supplementary Figure 2 from Overexpression of a Novel Activator of PAK4, the CDK5 Kinase–Associated Protein CDK5RAP3, Promotes Hepatocellular Carcinoma Metastasis
Supplementary Methods, Tables 1-2, Figures 1-4 from The Neuronal Differentiation Factor NeuroD1 Downregulates the Neuronal Repellent Factor Slit2 Expression and Promotes Cell Motility and Tumor Formation of Neuroblastoma
Authors: Huang Peng , Kishida Satoshi , Cao Dongliang , Murakami-Tonami Yuko , Mu Ping , Nakaguro Masato , Koide Naoshi , Takeuchi Ichiro , Onishi Akira , Kadomatsu Kenji
Published: April 2023

Supplementary Methods, Tables 1-2, Figures 1-4 from The Neuronal Differentiation Factor NeuroD1 Downregulates the Neuronal Repellent Factor Slit2 Expression and Promotes Cell Motility and Tumor Formation of Neuroblastoma
Supplementary Table 1 from Oncogenic PI3K Mutations Lead to NF-κB–Dependent Cytokine Expression following Growth Factor Deprivation
Authors: Hutti Jessica E. , Pfefferle Adam D. , Russell Sean C. , Sircar Mayukh , Perou Charles M. , Baldwin Albert S.
Published: April 2023

XLS file - 8.2MB, Complete microarray results
Supplementary Figure 4 from Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion
Authors: Dang Tuyen T. , Prechtl Amanda M. , Pearson Gray W.
Published: April 2023

PDF file - 7MB, Fibroblast induced collective invasion does not require a loss of epithelial character.
Supplementary Figure 3 from Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion
Authors: Dang Tuyen T. , Prechtl Amanda M. , Pearson Gray W.
Published: April 2023

PDF file - 2MB, Tracking the movement of breast cancer cells in spheroids.
Supplementary Video 7 from Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
Authors: Orth James D. , Kohler Rainer H. , Foijer Floris , Sorger Peter K. , Weissleder Ralph , Mitchison Timothy J.
Published: April 2023

Supplementary Video 7 from Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
Supplementary Video 1 from The White Adipose Tissue Used in Lipotransfer Procedures Is a Rich Reservoir of CD34+ Progenitors Able to Promote Cancer Progression
Authors: Martin-Padura Ines , Gregato Giuliana , Marighetti Paola , Mancuso Patrizia , Calleri Angelica , Corsini Chiara , Pruneri Giancarlo , Manzotti Michela , Lohsiriwat Visnu , Rietjens Mario , Petit Jean-Yves , Bertolini Francesco
Published: April 2023

AVI file - 3.7MB
Supplementary Table 1 from Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer
Authors: Yoo Young A. , Kang Myoung Hee , Lee Hyun Joo , Kim Baek-hui , Park Jong Kuk , Kim Hyun Koo , Kim Jun Suk , Oh Sang Cheul
Published: April 2023

PDF file - 15K
Supplementary Methods from Identification of Serum Biomarker Signatures Associated with Pancreatic Cancer
Authors: Wingren Christer , Sandström Anna , Segersvärd Ralf , Carlsson Anders , Andersson Roland , Löhr Matthias , Borrebaeck Carl A. K.
Published: April 2023

PDF file - 132K
Supplementary Figure 2 from FLT3 Ligand Enhances the Cancer Therapeutic Potency of Naked RNA Vaccines
Authors: Kreiter Sebastian , Diken Mustafa , Selmi Abderraouf , Diekmann Jan , Attig Sebastian , Hüsemann Yves , Koslowski Michael , Huber Christoph , Türeci Özlem , Sahin Ugur
Published: April 2023

PDF file - 1.37 MB
Supplementary Figure 1 from FLT3 Ligand Enhances the Cancer Therapeutic Potency of Naked RNA Vaccines
Authors: Kreiter Sebastian , Diken Mustafa , Selmi Abderraouf , Diekmann Jan , Attig Sebastian , Hüsemann Yves , Koslowski Michael , Huber Christoph , Türeci Özlem , Sahin Ugur
Published: April 2023

PDF file - 1.8 MB
Supplementary Table 1 from Adipokines Linking Obesity with Colorectal Cancer Risk in Postmenopausal Women
Authors: Ho Gloria Y.F. , Wang Tao , Gunter Marc J. , Strickler Howard D. , Cushman Mary , Kaplan Robert C. , Wassertheil-Smoller Sylvia , Xue Xiaonan , Rajpathak Swapnil N. , Chlebowski Rowan T. , Vitolins Mara Z. , Scherer Philipp E. , Rohan Thomas E.
Published: April 2023

PDF file - 66K, Median levels of adipokines by colorectal cancer risk factors in subcohort subjects from the WHI-OS Cohort,1994-2004
Supplementary Tables 1-2, Figures 1-5 from 6-Thioguanine Reactivates Epigenetically Silenced Genes in Acute Lymphoblastic Leukemia Cells by Facilitating Proteasome-mediated Degradation of DNMT1
Authors: Yuan Bifeng , Zhang Jing , Wang Hongxia , Xiong Lei , Cai Qian , Wang Tina , Jacobsen Steven , Pradhan Sriharsa , Wang Yinsheng
Published: April 2023

PDF file - 322K
Supplementary Figure 4 from Selectin Ligand Sialyl-Lewis x Antigen Drives Metastasis of Hormone-Dependent Breast Cancers
Authors: Julien Sylvain , Ivetic Aleksandar , Grigoriadis Anita , QiZe Ding , Burford Brian , Sproviero Daisy , Picco Gianfranco , Gillett Cheryl , Papp Suzanne L. , Schaffer Lana , Tutt Andrew , Taylor-Papadimitriou Joyce , Pinder Sarah E. , Burchell Joy M.
Published: April 2023

PDF file - 99K
Supplementary Figure 1 from Selectin Ligand Sialyl-Lewis x Antigen Drives Metastasis of Hormone-Dependent Breast Cancers
Authors: Julien Sylvain , Ivetic Aleksandar , Grigoriadis Anita , QiZe Ding , Burford Brian , Sproviero Daisy , Picco Gianfranco , Gillett Cheryl , Papp Suzanne L. , Schaffer Lana , Tutt Andrew , Taylor-Papadimitriou Joyce , Pinder Sarah E. , Burchell Joy M.
Published: April 2023

PDF file - 69K
Supplementary Figure 3 from STAT3 Is Necessary for Proliferation and Survival in Colon Cancer–Initiating Cells
Authors: Lin Li , Liu Aiguo , Peng Zhengang , Lin Huey-Jen , Li Pui-Kai , Li Chenglong , Lin Jiayuh
Published: April 2023

PDf file - 578K
Supplementary Figures 1-3 from Parallel High-Throughput RNA Interference Screens Identify PINK1 as a Potential Therapeutic Target for the Treatment of DNA Mismatch Repair–Deficient Cancers
Authors: Martin Sarah A. , Hewish Madeleine , Sims David , Lord Christopher J. , Ashworth Alan
Published: April 2023

Supplementary Figures 1-3 from Parallel High-Throughput RNA Interference Screens Identify PINK1 as a Potential Therapeutic Target for the Treatment of DNA Mismatch Repair–Deficient Cancers
Supplementary Table 1 from Chromosomal Instability Confers Intrinsic Multidrug Resistance
Authors: Lee Alvin J.X. , Endesfelder David , Rowan Andrew J. , Walther Axel , Birkbak Nicolai J. , Futreal P. Andrew , Downward Julian , Szallasi Zoltan , Tomlinson Ian P.M. , Howell Michael , Kschischo Maik , Swanton Charles
Published: April 2023

Supplementary Table 1 from Chromosomal Instability Confers Intrinsic Multidrug Resistance
Supplementary Table 2 from Definition of the Landscape of Promoter DNA Hypomethylation in Liver Cancer
Authors: Stefanska Barbara , Huang Jian , Bhattacharyya Bishnu , Suderman Matthew , Hallett Michael , Han Ze-Guang , Szyf Moshe
Published: April 2023

PDF file - 10K, Primer sequences used in mathylation analysis by pyrosequencing.
Supplementary Movie 1 from Fusion between Intestinal Epithelial Cells and Macrophages in a Cancer Context Results in Nuclear Reprogramming
Authors: Powell Anne E. , Anderson Eric C. , Davies Paige S. , Silk Alain D. , Pelz Carl , Impey Soren , Wong Melissa H.
Published: April 2023

Supplementary Movie 1 from Fusion between Intestinal Epithelial Cells and Macrophages in a Cancer Context Results in Nuclear Reprogramming
Supplementary Figures 1-4 from Cyclophosphamide Synergizes with Type I Interferons through Systemic Dendritic Cell Reactivation and Induction of Immunogenic Tumor Apoptosis
Authors: Schiavoni Giovanna , Sistigu Antonella , Valentini Mara , Mattei Fabrizio , Sestili Paola , Spadaro Francesca , Sanchez Massimo , Lorenzi Silvia , D'Urso Maria Teresa , Belardelli Filippo , Gabriele Lucia , Proietti Enrico , Bracci Laura
Published: April 2023

Supplementary Figures 1-4 from Cyclophosphamide Synergizes with Type I Interferons through Systemic Dendritic Cell Reactivation and Induction of Immunogenic Tumor Apoptosis
Supplementary Figures 1-5, Tables 1-2, and Methods and Materials from A Simple Approach to Cancer Therapy Afforded by Multivalent Pseudopeptides That Target Cell-Surface Nucleoproteins
Authors: Destouches Damien , Page Nicolas , Hamma-Kourbali Yamina , Machi Valérie , Chaloin Olivier , Frechault Sophie , Birmpas Charalampos , Katsoris Panagiotis , Beyrath Julien , Albanese Patricia , Maurer Marie , Carpentier Gilles , Strub Jean-Marc , Van Dorsselaer Alain , Muller Sylviane , Bagnard Dominique , Briand Jean Paul , Courty José
Published: April 2023

Supplementary Figures 1-5, Tables 1-2, and Methods and Materials from A Simple Approach to Cancer Therapy Afforded by Multivalent Pseudopeptides That Target Cell-Surface Nucleoproteins
Adobe PDF - sfigs_1-8.pdf from Cytoplasmic CUL9/PARC Ubiquitin Ligase Is a Tumor Suppressor and Promotes p53-Dependent Apoptosis
Authors: Pei Xin-Hai , Bai Feng , Li Zhijun , Smith Matthew D. , Whitewolf Gabrielle , Jin Ran , Xiong Yue
Published: April 2023

Adobe PDF - sfigs_1-8.pdf from Cytoplasmic CUL9/PARC Ubiquitin Ligase Is a Tumor Suppressor and Promotes p53-Dependent Apoptosis
Supplementary Figure 5 from Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide
Authors: Barsoum Ivraym B. , Hamilton Thomas K. , Li Xin , Cotechini Tiziana , Miles Ellen A. , Siemens D. Robert , Graham Charles H.
Published: April 2023

PDF file - 54K
Supplementary Figure 1 from Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide
Authors: Barsoum Ivraym B. , Hamilton Thomas K. , Li Xin , Cotechini Tiziana , Miles Ellen A. , Siemens D. Robert , Graham Charles H.
Published: April 2023

PDF file - 93K
Supplementary Figure 1 from EMT and Stem Cell–Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
Authors: Tellez Carmen S. , Juri Daniel E. , Do Kieu , Bernauer Amanda M. , Thomas Cindy L. , Damiani Leah A. , Tessema Mathewos , Leng Shuguang , Belinsky Steven A.
Published: April 2023

Supplementary Figure 1 from EMT and Stem Cell–Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
Supplementary Video 7 from Iodide Transporter NIS Regulates Cancer Cell Motility and Invasiveness by Interacting with the Rho Guanine Nucleotide Exchange Factor LARG
Authors: Lacoste Claire , Hervé Julie , Bou Nader Myriam , Dos Santos Alexandre , Moniaux Nicolas , Valogne Yannick , Montjean Rodrick , Dorseuil Olivier , Samuel Didier , Cassio Doris , Portulano Carla , Carrasco Nancy , Bréchot Christian , Faivre Jamila
Published: April 2023

MOV file - 3MB, Time lapse video microscopy of Hek293 cells stably expressing NISwt and transfected with siRNA scrumble
Supplementary Table 1 from Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling
Authors: Gasperini Paola , Espigol-Frigole Georgina , McCormick Peter J. , Salvucci Ombretta , Maric Dragan , Uldrick Thomas S. , Polizzotto Mark N. , Yarchoan Robert , Tosato Giovanna
Published: April 2023

PDF file - 98K
Supplementary Methods and Materials from Prohibitin Attenuates Colitis-Associated Tumorigenesis in Mice by Modulating p53 and STAT3 Apoptotic Responses
Authors: Kathiria Arwa S. , Neumann William L. , Rhees Jennifer , Hotchkiss Erin , Cheng Yulan , Genta Robert M. , Meltzer Stephen J. , Souza Rhonda F. , Theiss Arianne L.
Published: April 2023

PDF file - 70K
Supplementary Figure 4 from CXCR6 Upregulation Contributes to a Proinflammatory Tumor Microenvironment That Drives Metastasis and Poor Patient Outcomes in Hepatocellular Carcinoma
Authors: Gao Qiang , Zhao Ying-Jun , Wang Xiao-Ying , Qiu Shuang-Jian , Shi Ying-Hong , Sun Jian , Yi Yong , Shi Jie-Yi , Shi Guo-Ming , Ding Zhen-Bin , Xiao Yong-Sheng , Zhao Zhong-Hua , Zhou Jian , He Xiang-Huo , Fan Jia
Published: April 2023

PDF file - 1.6MB, The effects CXCR6-konckdown on expression of epithelial-to-mesenchymal transition markers and signaling molecules of hepatoma cells
Supplementary Figure 3 from CXCR6 Upregulation Contributes to a Proinflammatory Tumor Microenvironment That Drives Metastasis and Poor Patient Outcomes in Hepatocellular Carcinoma
Authors: Gao Qiang , Zhao Ying-Jun , Wang Xiao-Ying , Qiu Shuang-Jian , Shi Ying-Hong , Sun Jian , Yi Yong , Shi Jie-Yi , Shi Guo-Ming , Ding Zhen-Bin , Xiao Yong-Sheng , Zhao Zhong-Hua , Zhou Jian , He Xiang-Huo , Fan Jia
Published: April 2023

PDF file - 856K, Effects of CXCL16-knockdown on HCC cell invasion and cytokine secretion in vitro, and tumor growth in vivo
Supplementary Figure 1 from CXCR6 Upregulation Contributes to a Proinflammatory Tumor Microenvironment That Drives Metastasis and Poor Patient Outcomes in Hepatocellular Carcinoma
Authors: Gao Qiang , Zhao Ying-Jun , Wang Xiao-Ying , Qiu Shuang-Jian , Shi Ying-Hong , Sun Jian , Yi Yong , Shi Jie-Yi , Shi Guo-Ming , Ding Zhen-Bin , Xiao Yong-Sheng , Zhao Zhong-Hua , Zhou Jian , He Xiang-Huo , Fan Jia
Published: April 2023

PDF file - 2.4MB, Western blotting analysis of CXCR6 and CXCL16 in HCC and peritumoral liver tissues
Supplementary Figure 7 from MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive Metastasis
Authors: Chen Jian , Gallo Kathleen A.
Published: April 2023

PDF file - 38K, S178 phosphorylation of paxillin in human mammary epithelial and breast cancer cell lines
Supplementary Figure Legend from In Vivo Imaging of Drug-Induced Mitochondrial Outer Membrane Permeabilization at Single-Cell Resolution
Authors: Earley Sarah , Vinegoni Claudio , Dunham Joshua , Gorbatov Rostic , Feruglio Paolo Fumene , Weissleder Ralph
Published: April 2023

PDF file, 76KB.
Supplementary Figure 3 from MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive Metastasis
Authors: Chen Jian , Gallo Kathleen A.
Published: April 2023

PDF file - 129K, Effects of a second MLK3 siRNA on signaling in BT549 cells
Supplementary Figure 6 from Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response
Authors: Mittendorf Elizabeth A. , Alatrash Gheath , Qiao Na , Wu Yun , Sukhumalchandra Pariya , St. John Lisa S. , Philips Anne V. , Xiao Haile , Zhang Mao , Ruisaard Kathryn , Clise-Dwyer Karen , Lu Sijie , Molldrem Jeffrey J.
Published: April 2023

PDF file - 82K, Results showing the ability of neutrophil elastase to cleave recombinant cyclin E
Supplementary Figure 2 from MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive Metastasis
Authors: Chen Jian , Gallo Kathleen A.
Published: April 2023

PDF file - 46K, Effects of MLK and MAPK inhibitors on Ser 178 paxillin phosphorylation
Supplementary Figure 4 from Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response
Authors: Mittendorf Elizabeth A. , Alatrash Gheath , Qiao Na , Wu Yun , Sukhumalchandra Pariya , St. John Lisa S. , Philips Anne V. , Xiao Haile , Zhang Mao , Ruisaard Kathryn , Clise-Dwyer Karen , Lu Sijie , Molldrem Jeffrey J.
Published: April 2023

PDF file - 135K, Data evaluating the effect of elafin on inhibiting neutrophil elastase activity.
Supplementary Figure 2 from Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response
Authors: Mittendorf Elizabeth A. , Alatrash Gheath , Qiao Na , Wu Yun , Sukhumalchandra Pariya , St. John Lisa S. , Philips Anne V. , Xiao Haile , Zhang Mao , Ruisaard Kathryn , Clise-Dwyer Karen , Lu Sijie , Molldrem Jeffrey J.
Published: April 2023

PDF file - 94K, Figure showing uptake of neutrophil elastase by multiple breast cancer cell lines
Supplementary Figure 5 from Opposing Effects of Pigment Epithelium–Derived Factor on Breast Cancer Cell versus Neuronal Survival: Implication for Brain Metastasis and Metastasis-Induced Brain Damage
Authors: Fitzgerald Daniel P. , Subramanian Preeti , Deshpande Monika , Graves Christian , Gordon Ira , Qian Yongzhen , Snitkovsky Yeva , Liewehr David J. , Steinberg Seth M. , Paltán-Ortiz José D. , Herman Mary M. , Camphausen Kevin , Palmieri Diane , Becerra S. Patricia , Steeg Patricia S.
Published: April 2023

PDF file - 1.7MB
Supplementary Figure 3 from Opposing Effects of Pigment Epithelium–Derived Factor on Breast Cancer Cell versus Neuronal Survival: Implication for Brain Metastasis and Metastasis-Induced Brain Damage
Authors: Fitzgerald Daniel P. , Subramanian Preeti , Deshpande Monika , Graves Christian , Gordon Ira , Qian Yongzhen , Snitkovsky Yeva , Liewehr David J. , Steinberg Seth M. , Paltán-Ortiz José D. , Herman Mary M. , Camphausen Kevin , Palmieri Diane , Becerra S. Patricia , Steeg Patricia S.
Published: April 2023

PDF file - 1.3MB
Supplementary Figure 4 from Global Quantitative Phosphoproteome Analysis of Human Tumor Xenografts Treated with a CD44 Antagonist
Authors: Weigand Stefan , Herting Frank , Maisel Daniela , Nopora Adam , Voss Edgar , Schaab Christoph , Klammer Martin , Tebbe Andreas
Published: April 2023

PDF file - 105K, Background optimization of p-ERK1/2-ELISA by use of alternative blocking buffers
Supplementary Tables 1-6 from Alternate Splicing of the p53 Inhibitor HDMX Offers a Superior Prognostic Biomarker than p53 Mutation in Human Cancer
Authors: Lenos Kristiaan , Grawenda Anna M. , Lodder Kirsten , Kuijjer Marieke L. , Teunisse Amina F.A.S. , Repapi Emmanouela , Grochola Lukasz F. , Bartel Frank , Hogendoorn Pancras C.W. , Wuerl Peter , Taubert Helge , Cleton-Jansen Anne-Marie , Bond Gareth L. , Jochemsen Aart G.
Published: April 2023

PDF file - 169K, Further detailed information is presented regarding both the cell panels and patient cohorts
Supplementary Methods, Figure Legends 1-3, Table Legends 1-6 from Alternate Splicing of the p53 Inhibitor HDMX Offers a Superior Prognostic Biomarker than p53 Mutation in Human Cancer
Authors: Lenos Kristiaan , Grawenda Anna M. , Lodder Kirsten , Kuijjer Marieke L. , Teunisse Amina F.A.S. , Repapi Emmanouela , Grochola Lukasz F. , Bartel Frank , Hogendoorn Pancras C.W. , Wuerl Peter , Taubert Helge , Cleton-Jansen Anne-Marie , Bond Gareth L. , Jochemsen Aart G.
Published: April 2023

PDF file - 89K
Supplementary Figure 3 from Alternate Splicing of the p53 Inhibitor HDMX Offers a Superior Prognostic Biomarker than p53 Mutation in Human Cancer
Authors: Lenos Kristiaan , Grawenda Anna M. , Lodder Kirsten , Kuijjer Marieke L. , Teunisse Amina F.A.S. , Repapi Emmanouela , Grochola Lukasz F. , Bartel Frank , Hogendoorn Pancras C.W. , Wuerl Peter , Taubert Helge , Cleton-Jansen Anne-Marie , Bond Gareth L. , Jochemsen Aart G.
Published: April 2023

PDF file - 51K, High HDMX-S/HDMX-FL ratios, but not p53 gene mutation associates with worse outcome in soft tissue sarcoma patients
Supplementary Figures 6-7 from An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis
Authors: Huang Xiumei , Dong Ying , Bey Erik A. , Kilgore Jessica A. , Bair Joseph S. , Li Long-Shan , Patel Malina , Parkinson Elizabeth I. , Wang Yiguang , Williams Noelle S. , Gao Jinming , Hergenrother Paul J. , Boothman David A.
Published: April 2023

PDF file - 533K, Intracellular ER Calcium release is required for NQO1-dependent lethality after DNQ. Supplemental Figure 7. NQO1-dependent therapeutic window in vitro of DNQ in NSCLC cells.
Supplementary Methods, Figure Legends 1-7 from Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
Authors: Tamada Mayumi , Nagano Osamu , Tateyama Seiji , Ohmura Mitsuyo , Yae Toshifumi , Ishimoto Takatsugu , Sugihara Eiji , Onishi Nobuyuki , Yamamoto Takehiro , Yanagawa Hiroshi , Suematsu Makoto , Saya Hideyuki
Published: April 2023

PDF file - 154K
Supplementary Figure 7 from Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
Authors: Tamada Mayumi , Nagano Osamu , Tateyama Seiji , Ohmura Mitsuyo , Yae Toshifumi , Ishimoto Takatsugu , Sugihara Eiji , Onishi Nobuyuki , Yamamoto Takehiro , Yanagawa Hiroshi , Suematsu Makoto , Saya Hideyuki
Published: April 2023

PDF file - 264K
Supplementary Table 4 from Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
Authors: Lee Sangjun , Stewart Sheila , Nagtegaal Iris , Luo Jingqin , Wu Yun , Colditz Graham , Medina Dan , Allred D. Craig
Published: April 2023

PDF file - 58K, Growth and Progression of MIND Xenografts of DCIS.COM, hDCIS.01 and SUM225 transduced with shRNAi against candidate DCIS suppressor genes
Supplementary Figure 4 from Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
Authors: Tamada Mayumi , Nagano Osamu , Tateyama Seiji , Ohmura Mitsuyo , Yae Toshifumi , Ishimoto Takatsugu , Sugihara Eiji , Onishi Nobuyuki , Yamamoto Takehiro , Yanagawa Hiroshi , Suematsu Makoto , Saya Hideyuki
Published: April 2023

PDF file - 329K
Supplementary Table 1 from Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
Authors: Lee Sangjun , Stewart Sheila , Nagtegaal Iris , Luo Jingqin , Wu Yun , Colditz Graham , Medina Dan , Allred D. Craig
Published: April 2023

PDF file - 53K, Summary of samples used in this and in previous studies directly comparing gene expression in human ductal carcinoma in situ (DCIS) and invasive Breast Cancer
Supplementary Figure 4 from Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
Authors: Lee Sangjun , Stewart Sheila , Nagtegaal Iris , Luo Jingqin , Wu Yun , Colditz Graham , Medina Dan , Allred D. Craig
Published: April 2023

PDF file - 154K, Representative photographs of DCIS in MIND xenografts of DCIS.COM immunostained with antibodies recognizing myoepithelial cells
Supplementary Figure 3 from Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
Authors: Lee Sangjun , Stewart Sheila , Nagtegaal Iris , Luo Jingqin , Wu Yun , Colditz Graham , Medina Dan , Allred D. Craig
Published: April 2023

PDF file - 118K, In Vitro Results (impact of gene knockdown on the ability of cells to grow)
Supplementary Table 1 from Endothelial Expression of TNF Receptor-1 Generates a Proapoptotic Signal Inhibited by Integrin α6β1 in Glioblastoma
Authors: Huang Ping , Rani M.R. Sandhya , Ahluwalia Manmeet S. , Bae Eunnyung , Prayson Richard A. , Weil Robert J. , Nowacki Amy S. , Hedayat Hirad , Sloan Andrew E. , Lathia Justin D. , Rich Jeremy N. , Tipps Russell , Gladson Candece L.
Published: April 2023

PDF file - 71K, Increased Expression of TNFalpha, TNF-R1 and TNF-R2 in the ECs in Untreated GBM
Supplementary Figure 3 from Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice
Authors: Tsoli Maria , Moore Melissa , Burg Dominic , Painter Arran , Taylor Ryland , Lockie Sarah H. , Turner Nigel , Warren Alessandra , Cooney Greg , Oldfield Brian , Clarke Stephen , Robertson Graham
Published: April 2023

PDF file - 178K, Expression of genes involved in lipolysis and thermogenesis in animals bearing the non-cachectic C26 tumor
Supplementary Figure 7 from Endothelial Expression of TNF Receptor-1 Generates a Proapoptotic Signal Inhibited by Integrin α6β1 in Glioblastoma
Authors: Huang Ping , Rani M.R. Sandhya , Ahluwalia Manmeet S. , Bae Eunnyung , Prayson Richard A. , Weil Robert J. , Nowacki Amy S. , Hedayat Hirad , Sloan Andrew E. , Lathia Justin D. , Rich Jeremy N. , Tipps Russell , Gladson Candece L.
Published: April 2023

PDF file - 2.1MB, Double-labeling for cFLIP and vWf in endothelial cells of GBM and normal brain samples
Supplementary Figure 6 from Endothelial Expression of TNF Receptor-1 Generates a Proapoptotic Signal Inhibited by Integrin α6β1 in Glioblastoma
Authors: Huang Ping , Rani M.R. Sandhya , Ahluwalia Manmeet S. , Bae Eunnyung , Prayson Richard A. , Weil Robert J. , Nowacki Amy S. , Hedayat Hirad , Sloan Andrew E. , Lathia Justin D. , Rich Jeremy N. , Tipps Russell , Gladson Candece L.
Published: April 2023

PDF file - 1MB, Absence of cFLIP expression in human GBM cells and human GBM stem cells plated on laminin
Supplementary Figure 3 from Endothelial Expression of TNF Receptor-1 Generates a Proapoptotic Signal Inhibited by Integrin α6β1 in Glioblastoma
Authors: Huang Ping , Rani M.R. Sandhya , Ahluwalia Manmeet S. , Bae Eunnyung , Prayson Richard A. , Weil Robert J. , Nowacki Amy S. , Hedayat Hirad , Sloan Andrew E. , Lathia Justin D. , Rich Jeremy N. , Tipps Russell , Gladson Candece L.
Published: April 2023

PDF file - 481K, Dose-dependent TNF�\�{induced apoptosis of primary brain ECs.
Supplementary Figure 1 from Endothelial Expression of TNF Receptor-1 Generates a Proapoptotic Signal Inhibited by Integrin α6β1 in Glioblastoma
Authors: Huang Ping , Rani M.R. Sandhya , Ahluwalia Manmeet S. , Bae Eunnyung , Prayson Richard A. , Weil Robert J. , Nowacki Amy S. , Hedayat Hirad , Sloan Andrew E. , Lathia Justin D. , Rich Jeremy N. , Tipps Russell , Gladson Candece L.
Published: April 2023

PDF file - 132K, Double-labeling of vWf and TNF�\, TNF-R1, or TNF-R2 in tumor-associated ECs of GBM.
Supplementary Methods, Figures 1-7, Tables 1-7 from Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem–Like Cells with Macrophages and Stromal Cells
Authors: Okuda Hiroshi , Kobayashi Aya , Xia Bo , Watabe Misako , Pai Sudha K. , Hirota Shigeru , Xing Fei , Liu Wen , Pandey Puspa R. , Fukuda Koji , Modur Vishnu , Ghosh Arnab , Wilber Andrew , Watabe Kounosuke
Published: April 2023

PDF file - 2.6MB
Supplementary Tables 1-5 from 3′-UTR and Functional Secretor Haplotypes in Mannose-Binding Lectin 2 Are Associated with Increased Colon Cancer Risk in African Americans
Authors: Zanetti Krista A. , Haznadar Majda , Welsh Judith A. , Robles Ana I. , Ryan Bríd M. , McClary Andrew C. , Bowman Elise D. , Goodman Julie E. , Bernig Toralf , Chanock Stephen J. , Harris Curtis C.
Published: April 2023

PDF file - 123K
Supplementary Table 2 from Circulating Insulin-Like Growth Factors and IGF-Binding Proteins in PSA-Detected Prostate Cancer: The Large Case–Control Study ProtecT
Authors: Rowlands Mari-Anne , Holly Jeff M.P. , Gunnell David , Donovan Jenny , Lane J. Athene , Hamdy Freddie , Neal David E. , Oliver Steven , Smith George Davey , Martin Richard M.
Published: April 2023

PDF file - 83K
Supplementary Table 2 from A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
Authors: Kulbe Hagen , Chakravarty Probir , Leinster D. Andrew , Charles Kellie A. , Kwong Joseph , Thompson Richard G. , Coward Jermaine I. , Schioppa Tiziana , Robinson Stephen C. , Gallagher William M. , Galletta Laura , Salako Michael A. , Smyth John F. , Hagemann Thorsten , Brennan Donal J. , Bowtell David D. , Balkwill Frances R.
Published: April 2023

PDF file - 294K
Supplementary Figure 8 from TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Authors: Duvvuri Umamaheswar , Shiwarski Daniel J. , Xiao Dong , Bertrand Carol , Huang Xin , Edinger Robert S. , Rock Jason R. , Harfe Brian D. , Henson Brian J. , Kunzelmann Karl , Schreiber Rainer , Seethala Raja S. , Egloff Ann Marie , Chen Xing , Lui Vivian W. , Grandis Jennifer R. , Gollin Susanne M.
Published: April 2023

PDF file - 109K, TMEM16A inhibition with T16A-inh01 (A01) alone or in combination with the MEK/ERK inhibitor UO126 leads to decreased tumor cell viability in vitro. UM-SCC1 and T24 cells were treated with increasing concentrations of A01. A dose dependent reduction in cell viability was observed (A, B *P<0.05, **P<0.01, ***P<0.001). Additionally, treatment of SCC1 and T24 cells with TMEM16A shRNA led to a decrease in cell viability that in combination with inhibition of ERK1/2 had an additive effect (C, D; mean � SEM; n=4, *P<0.05, **P<0.01). The chemical structure of AO1 is shown in panel E.
Supplementary Figure Legends 1-4 from A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
Authors: Kulbe Hagen , Chakravarty Probir , Leinster D. Andrew , Charles Kellie A. , Kwong Joseph , Thompson Richard G. , Coward Jermaine I. , Schioppa Tiziana , Robinson Stephen C. , Gallagher William M. , Galletta Laura , Salako Michael A. , Smyth John F. , Hagemann Thorsten , Brennan Donal J. , Bowtell David D. , Balkwill Frances R.
Published: April 2023

PDF file - 83K
Supplementary Figure 5 from TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Authors: Duvvuri Umamaheswar , Shiwarski Daniel J. , Xiao Dong , Bertrand Carol , Huang Xin , Edinger Robert S. , Rock Jason R. , Harfe Brian D. , Henson Brian J. , Kunzelmann Karl , Schreiber Rainer , Seethala Raja S. , Egloff Ann Marie , Chen Xing , Lui Vivian W. , Grandis Jennifer R. , Gollin Susanne M.
Published: April 2023

PDF file - 69K, TMEM16A knock-down alters progression through cell cycle. T24 cells were transfected with TMEM16A siRNA or non-targeting control. These cells were then subjected to cell cycle analysis using FACS with propidium iodide staining. Transient knock-down of TMEM16A by siRNA blocks cell cycle progression from G1 to S phase (E; mean � SEM; n=3, **P<0.01, ***P<0.001). Caspase 3/7 activation was measured as a surrogate for apoptosis in T24 control and TMEM16A overexpressing cells. TMEM16A overexpression led to a reduction in caspase3/7 activity (B). Control and TMEM16A overexpressing cells were treated with AZD6244 (a specific ERK1/2 inhibitor), leading to an abrogation of TMEM16A-induced cell growth (C). Genetic knock-down of ERK1/2 with siRNA also abolished TMEM16A-induced growth (D).
Supplementary Figure 4 from TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Authors: Duvvuri Umamaheswar , Shiwarski Daniel J. , Xiao Dong , Bertrand Carol , Huang Xin , Edinger Robert S. , Rock Jason R. , Harfe Brian D. , Henson Brian J. , Kunzelmann Karl , Schreiber Rainer , Seethala Raja S. , Egloff Ann Marie , Chen Xing , Lui Vivian W. , Grandis Jennifer R. , Gollin Susanne M.
Published: April 2023

PDF file - 407K, TMEM16A overexpression promotes cell proliferation in HEK-293T cells. TMEM16A overexpression induced cellular proliferation (*P<0.05). A representative immunoblot is shown (A). TMEM16A confers anchorage-independent viability in keratinocytes. Spontaneously immortalized oral keratinocytes were transduced with TMEM16A expressing virus or control (VC) and anchorage independent viability was evaluated. TMEM16A overexpression increases viability in anchorage independent conditions (B, p<0.05). TMEM16A knockdown induced growth retardation in SCCHN cells Cal33 and PCI-15B (C). Spontaneously immortalized wild-type MEFs expressing H-rasQ61L were transduced with retroviruses encoding TMEM16A or a hypo-morphic version of TMEM16A (TMEM16A-K610A). Focus formation was determined by crystal violet staining. TMEM16A overexpression induces a 3-fold increase in foci formation, the experiment was repeated several times in triplicate (D, p<0.05). Clonogenic assay was used to demonstrate increased colony formation after TMEM16A overexpression in T24, UM-SCC1 and immortalized keratinocytes (E).
Supplementary Figure 2 from A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
Authors: Kulbe Hagen , Chakravarty Probir , Leinster D. Andrew , Charles Kellie A. , Kwong Joseph , Thompson Richard G. , Coward Jermaine I. , Schioppa Tiziana , Robinson Stephen C. , Gallagher William M. , Galletta Laura , Salako Michael A. , Smyth John F. , Hagemann Thorsten , Brennan Donal J. , Bowtell David D. , Balkwill Frances R.
Published: April 2023

PDF file - 279K
Supplementary Table 3 from Mammalian Sterile 20–like Kinase 1 Suppresses Lymphoma Development by Promoting Faithful Chromosome Segregation
Authors: Kim Tae-Shin , Lee Da-Hye , Kim Sang Kyum , Shin So Youn , Seo Eul-Ju , Lim Dae-Sik
Published: April 2023

PDF file - 18K, Mitotic chromosome count analysis with MEFs from various genotypes
Supplementary Figure 7 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Authors: Waaler Jo , Machon Ondrej , Tumova Lucie , Dinh Huyen , Korinek Vladimir , Wilson Steven Ray , Paulsen Jan Erik , Pedersen Nina Marie , Eide Tor J. , Machonova Olga , Gradl Dietmar , Voronkov Andrey , von Kries Jens Peter , Krauss Stefan
Published: April 2023

PDF file - Human liver microsome (HLM) test of JW55 (A), weight measurement of ApcCKO/CKOLgr5-CreERT2+ mice treated with JW55 or vehicle (B) and an example on quantification of tumor number and area using Ellipse software (C).
Supplementary Figure 6 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Authors: Waaler Jo , Machon Ondrej , Tumova Lucie , Dinh Huyen , Korinek Vladimir , Wilson Steven Ray , Paulsen Jan Erik , Pedersen Nina Marie , Eide Tor J. , Machonova Olga , Gradl Dietmar , Voronkov Andrey , von Kries Jens Peter , Krauss Stefan
Published: April 2023

PDF file - 178K, Pictures of the ileum (DMSO treated small intestine) that show delineated flat adenomas (A), with a few goblet cells (arrow)(B), a transition between normal epithelium and neoplastic glands (arrow) (C) and aberrant crypt foci in areas with no obvious adenoma formation (arrows) (D).
Supplementary Figure 5 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Authors: Waaler Jo , Machon Ondrej , Tumova Lucie , Dinh Huyen , Korinek Vladimir , Wilson Steven Ray , Paulsen Jan Erik , Pedersen Nina Marie , Eide Tor J. , Machonova Olga , Gradl Dietmar , Voronkov Andrey , von Kries Jens Peter , Krauss Stefan
Published: April 2023

PDF file - 139K, A fluorescence polarization competition assay was performed using a fluorescein-tagged analog of XAV939 (XAV939-Fluorescein) versus JW55 and a structurally similar but inactive analog of JW55.
Supplementary Figure Legends 1-5 from Mammalian Sterile 20–like Kinase 1 Suppresses Lymphoma Development by Promoting Faithful Chromosome Segregation
Authors: Kim Tae-Shin , Lee Da-Hye , Kim Sang Kyum , Shin So Youn , Seo Eul-Ju , Lim Dae-Sik
Published: April 2023

PDF file - 32K
Supplementary Figure 3 from Mammalian Sterile 20–like Kinase 1 Suppresses Lymphoma Development by Promoting Faithful Chromosome Segregation
Authors: Kim Tae-Shin , Lee Da-Hye , Kim Sang Kyum , Shin So Youn , Seo Eul-Ju , Lim Dae-Sik
Published: April 2023

PDF file - 151K, Wild-type thymocytes show normal chromosomal segregation during mitosis
Supplementary Figure 1 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Authors: Waaler Jo , Machon Ondrej , Tumova Lucie , Dinh Huyen , Korinek Vladimir , Wilson Steven Ray , Paulsen Jan Erik , Pedersen Nina Marie , Eide Tor J. , Machonova Olga , Gradl Dietmar , Voronkov Andrey , von Kries Jens Peter , Krauss Stefan
Published: April 2023

PDF file - 160K, Determination of IC50-values in HEK293 cells (ST-Luc) and biochemical assays (TNKS1/2 and PARP) using XLfit
Supplementary Figures 1-2 from Pocket Proteins Suppress Head and Neck Cancer
Authors: Shin Myeong-Kyun , Pitot Henry C. , Lambert Paul F.
Published: April 2023

PDF file - 473K
Supplementary Materials and Methods, Figure Legends 1-6 from miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4
Authors: Chen Hsin-Yi , Lin Yu-Min , Chung Hsiang-Ching , Lang Yaw-Dong , Lin Ching-Jung , Huang John , Wang Wei-Chi , Lin Feng-Mao , Chen Zhen , Huang Hsien-Da , Shyy John Y.-J. , Liang Jin-Tung , Chen Ruey-Hwa
Published: April 2023

PDF file - 52K, Supplementary materials includes statistical analysis, antibodies and reagent information, supplementary references, and supplementary figure legend
Supplementary Figure 5 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity
Authors: Pietra Gabriella , Manzini Claudia , Rivara Silvia , Vitale Massimo , Cantoni Claudia , Petretto Andrea , Balsamo Mirna , Conte Romana , Benelli Roberto , Minghelli Simona , Solari Nicola , Gualco Marina , Queirolo Paola , Moretta Lorenzo , Mingari Maria Cristina
Published: April 2023

PDF file - 80K
Supplementary Figure 4 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity
Authors: Pietra Gabriella , Manzini Claudia , Rivara Silvia , Vitale Massimo , Cantoni Claudia , Petretto Andrea , Balsamo Mirna , Conte Romana , Benelli Roberto , Minghelli Simona , Solari Nicola , Gualco Marina , Queirolo Paola , Moretta Lorenzo , Mingari Maria Cristina
Published: April 2023

PDF file - 68K
Supplementary Figure 3 from miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4
Authors: Chen Hsin-Yi , Lin Yu-Min , Chung Hsiang-Ching , Lang Yaw-Dong , Lin Ching-Jung , Huang John , Wang Wei-Chi , Lin Feng-Mao , Chen Zhen , Huang Hsien-Da , Shyy John Y.-J. , Liang Jin-Tung , Chen Ruey-Hwa
Published: April 2023

PDF file - 51K, Re-expression of DAPK and KLF4 suppresses miR-103/107-induced migration and invasion in normoxia
Supplementary Figure 3 from Jab1/CSN5 Negatively Regulates p27 and Plays a Role in the Pathogenesis of Nasopharyngeal Carcinoma
Authors: Pan Yunbao , Zhang Qingxiu , Tian Ling , Wang Xin , Fan Xiaohang , Zhang Huizhong , Claret Francois X. , Yang Huiling
Published: April 2023

PDF file - 94K
Supplementary Figure Legends 1-5 from Hedgehog Signaling Inhibition Blocks Growth of Resistant Tumors through Effects on Tumor Microenvironment
Authors: Heller Emanuela , Hurchla Michelle A. , Xiang Jingyu , Su Xinming , Chen Sara , Schneider Jochen , Joeng Kyu-Sang , Vidal Marcos , Goldberg Leah , Deng Hongju , Hornick Mary C. , Prior Julie L. , Piwnica-Worms David , Long Fanxin , Cagan Ross , Weilbaecher Katherine N.
Published: April 2023

PDF file - 100K
Supplementary Figure 2 from Jab1/CSN5 Negatively Regulates p27 and Plays a Role in the Pathogenesis of Nasopharyngeal Carcinoma
Authors: Pan Yunbao , Zhang Qingxiu , Tian Ling , Wang Xin , Fan Xiaohang , Zhang Huizhong , Claret Francois X. , Yang Huiling
Published: April 2023

PDF file - 137K
Supplementary Figure 2 from Hedgehog Signaling Inhibition Blocks Growth of Resistant Tumors through Effects on Tumor Microenvironment
Authors: Heller Emanuela , Hurchla Michelle A. , Xiang Jingyu , Su Xinming , Chen Sara , Schneider Jochen , Joeng Kyu-Sang , Vidal Marcos , Goldberg Leah , Deng Hongju , Hornick Mary C. , Prior Julie L. , Piwnica-Worms David , Long Fanxin , Cagan Ross , Weilbaecher Katherine N.
Published: April 2023

PDf file - 4.9MB