bluuebunny/crossref_metadata_2025 huggingface dataset:
mRNA Purification: Technology Aspects and Impurities TFF, Chromatography, UF/DF (Resins, Magnetic Beads, Monoliths)
Authors: Luisetto Mauro
Published: June 2023

m RNA VACCINE production like other biopharmaceutical need various purification stages in the manifacturing process. In this process are used techniques like: (TFF) tangential flow filtration followed by different chromatographic procedure (affinity and ion exchange separation) with various kinds of resin and then UF/DF technique (Ultrafiltration-diafiltration). So it is of interest to verify that the materials used for this kind of procedure is solid phases or for the membrane and if released impurity in the final product. For Silica-based Reversed-Phase packing’s, a carbon load percentage indicates the amount of functional bonded phase attached to the Silica-base material. Aim of this work is to investigate the role played by these characteristics in the separation process of mRNA. Because this parameter influence the retention time it is interesting to evaluate the use in separation technique of biopharmaceuticals and this also is for the carbon coated silica columns. Silica gel for chromatography can be produced by systemic process but also form Rice treated at high temperature. What kind of effect can be played using an high level of carbon coated silica material on the final purified product? The graphitic particle can be found as impurity during the manufacturing process of these resins? And what is the role played by carbon (graphene-quantum dots) membrane as reported in various research application?
Difloxacin Disposition and Residues in Broiler Chickens
Authors: Errecalde Carlos
Published: June 2023

Difloxacin disposition in broiler chickens was studied, with the objective of establishing pharmacokinetic parameters in plasma and tissues and estimating a withdrawal period. Forty-two adult chickens were divided into 14 groups of 3 individuals each, which received a 10 mg/kg single oral dose of difloxacin after a period of fasting between 12 hours before and 3 hours after administration. Each batch was sacrificed at pre-established times, and blood, muscle lung, liver, skin and kidney samples were obtained in a period up to 120 hours post application. Assay consisted in the extraction of the analyte, its separation and quantification by high performance liquid chromatography (HPLC). Mean plasma and tissue concentrations of difloxacin by time were analyzed with the PK Solution software. Oral application determines rapid absorption, moderate plasmatic permanence and extensive tissue distribution. The analysis of residual concentrations in tissues using WT 1.4 software calculated the withdrawal period, based on maximum residue limits (MRL) of 300, 1900, 400, 600 and 300 µg/kg, established for muscle, liver, skin, kidney and lung, respectively, a withdrawal period of 3 days is estimated for muscle, liver and skin and 5 days for kidney and lung.
COVID 19 in Children
Authors: Jabir Al awwadi Najim A
Published: June 2023

Corona is a common viral disease that can be transmitted between humans and different types of animals, meaning it can be transmitted between different races and types of living organisms. It is characterized as having broad-spectrum disease symptoms that differ from one patient to another in their severity and type. In the last months of 2019, a storm of infection with the Corona virus appeared in the Chinese city of Wuhan, with symptoms that were almost different in severity and led to deaths in some infections. The virus was characterized by its rapid spread among people, which surprised researchers, doctors and people in that city and in China in general. Which challenged Chinese researchers and scientists to investigate the type and nature of the causative agent, so they were able to diagnose Corona virus (Cove 2).
Drug Therapy Problems among Patients with both Cardiovascular Diseases and Diabetes Mellitus in A Sub-Saharan African Referral Hospital
Authors: Mugane George
Published: June 2023

Background: Patients with both type 2 diabetes mellitus and cardiovascular disease receive multiple medications but there are limited studies on drug therapy problems among them in Sub-Saharan Africa. Objective: To determine the predictors of drug therapy problems among adult patients with both type 2 diabetes and cardiovascular diseases. Setting: Kenyatta National Hospital. Method: A cross-sectional study involving 180 adult patients with both comorbidities was conducted. Data collected included sociodemographic and clinical characteristics, medications prescribed and drug therapy problems. Data was analyzed using STATA v.13 at p<0.05. Main outcome measures: Drug therapy problems and their predictors. Results: Majority (91.1%) of the patients had at least one drug therapy problems; most common being untreated indication, 87 (48.3%) which was significantly associated with furosemide use (p=0.003) and >72 months living with diabetes (p=0.007). Non-adherence was associated with the perception of disease control or cure (p<0.001). Under dosing of medications was significant in poor glycemic control (=<0.001) and poor blood pressure control (p=0.012). Conclusion: Clinicians should be aware that patients with both comorbidities are more likely to be under dosed, non-adhere to treatment or have other untreated conditions. Recommendation for Practice • Health care practitioners need to continuously monitor the drug therapy problems among patients with comorbidities • Prescribers should holistically manage patients specifically by identification of untreated conditions • Diabetic hypertensive patients who are not responding to treatment should always be assessed for under dosing and nonadherence • Kenyatta National Hospital should be encouraged to have counseling programs, especially to patients with long standing comorbidities, to improve adherence.
Perspectives for Treating Alzheimer’s Disease: A Review on Indigeous Plants for Alzheimer Disease
Authors: R Rao Janhavi
Published: June 2023

Alzheimer’s disease (AD) is one of the most common forms of dementia. The salient pathological hallmarks of AD are extracellular accumulation of amyloid β peptide (Aβ) forming senile plaques (SP), the aggregates of intracellular neurofibrillary tangles (NFTs) and microglial changes in the brain. N-Methyl-D-aspartate receptor (NMDAR), a member of ionotropic glutamate receptor (iGluR), plays an indispensable mantle in maintaining calcium homeostasis and synaptic plasticity. Activation of NMDAR requires co-binding of glycine and glutamate along with postsynaptic depolarization. Upon activation it facilitates the entry of calcium ion into the neurons. The GluN2B subunit of NMDAR has been involved into the direct interaction with Aβ and tau protein and also in the activation of microglia, thus leading to pathophysiology of AD. N-methyl-d-aspartate receptors (NMDARs) mediated excitotoxicity has been implicated in multi-neurodegenerative diseases. Owing to dearth of efficacy and adverse effects of NMDA receptor antagonists, search for herbal remedies acting like salutary agents is a dynamic expanse of investigation to contest neurodegenerative disease. In this review we have delved deep into different NMDA antagonist and their pivotal role in preventing Aβ-mediated synaptic plasticity and their potential role as therapeutic target to curtail AD.
Marine Actinomycetes the Past, the Present and the Future
Authors: A Elkhateeb Waill
Published: June 2023

In the field of exploring new natural sources for biologically active products with economic importance, the marine environment draws particular attention due to the noticeable diversity and extreme conditions; it is well known that the marine environment is a valuable source of biological and therapeutic compounds with great value. The marine environment represents a novel source for the discovery of new secondary metabolites including antibiotic, antiviral, antitumor, antifouling agents, as well as enzymes. Marine actinomycetes are widely distributed through the marine environment from shallow to sea sediments. The secondary metabolites obtained from such marine actinomycetes have proved their value in different industries due to their unique properties and structures. This review focuses on the importance of marine actinomycetes as well as their secondary metabolites. The development of new technologies for marine actinomycetes bioprospection is very promising, leading to the discovery of high-quality value products with biotechnological and medical applications.
Medicinal Chemistry of Curcumin and its Therapeutic Approaches from Ancient Medicine to Recent Potential
Authors: Raut Vaibhav
Published: June 2023

Many natural medicinal plants have been utilised to cure a range of disorders since ancient times and are regarded as a possible source of phytochemicals for the creation of new medications. One of these is curcumin, a bioactive molecule that is easily available, affordable, and harmless. It is a vital, naturally occurring, highly lipophilic and phenolic chemical. Curcumin (diferuloylmethane), a low-molecular-weight chemical derived from the roots of Curcuma longa L. (family Zingiberaceae), is mostly used as a curry spice, flavouring agent, insect repellant, food colouring agent, traditional medication, and cosmetic component. Curcumin is a tautomeric molecule that exists in organic solvents as an enolic form and in water as a keto form. Though inconclusive, epidemiological findings show that turmeric intake may lessen the incidence of some malignancies and provide other beneficial biological benefits in people. Turmeric’s biological benefits have been linked to its ingredient curcumin, which has been extensively researched for its anti-inflammatory, anti-ulcer, anti-diabetic, anti-viral, antioxidant, wound healing, and anti-cancer properties. Curcumin is a low-toxicity nutraceutical that has been utilised successfully in a variety of medical ailments, as discussed in this article.
A Review on Ganoderic Acid, Cordycepin and Usnic Acid, an interesting Natural Compounds from Mushrooms and Lichens
Authors: Elkhateeb Waill A
Published: June 2023

Mushrooms and lichens are generous source of nutritional and medicinal compounds, and medicinal uses of the mushrooms and lichens still need to be worked out for their biological activities. This review aims to put ganoderic acid, cordycepin and usnic acid under light spot through representing their important as biological activities exerted by ever one. Further studies and investigations are fortified in order to find more about these interesting natural products.
Contents of Nineteen Chemical Elements in Thyroid Benign Nodules and Tissue adjacent to Nodules investigated using X-Ray Fluorescence and Neutron Activation Analysis
Authors: Zaichick V
Published: June 2023

Thyroid benign nodules (TBNs) are the most common diseases of this endocrine gland and are common worldwide. The etiology and pathogenesis of TBNs must be considered as multifactorial. The present study was performed to clarify the role of some chemical elements (ChEs) in the etiology of these thyroid disorders. Thyroid tissue levels of Ag, Ca, Cl, Co, Cr, Cu, Fe, Hg, I, K, Mg, Mn, Na, Rb, Sb, Sc, Se, Sr, and Zn were prospectively evaluated in nodular tissue and tissue adjacent to nodules of 79 patients with TBNs. Measurements were performed using X-ray fluorescence and instrumental neutron activation analysis. Results of the study were additionally compared with previously obtained data for the same ChEs in “normal” thyroid tissue. It was observed that mass fractions of Ag, Cl, Co, Cr, Cu, Fe, Hg, Mn, Na, and Sc contents in “nodular” tissue were higher, while Ca and I content was lower in comparison with contents of these ChEs in normal gland. Mass fractions of Ag, Cl, Hg, Na, and Rb in “adjacent” group of samples were approximately 31, 2.7, 32, 1.6, and 1.3 times higher, respectively, than in “normal” thyroid. Contents of Cr, Fe, Sc, and Se were lower, while mass fraction of Hg and I higher in “adjacent” group of samples in comparison with nodular tissue. At that, level of I in “adjacent” group of samples was over 2 times higher than in nodular tissue and almost equals the normal value. This study provides evidence on many ChEs level alteration in nodular and adjacent to nodule tissue and shows the necessity to continue ChEs research of TBNs. The little reduced level of I content in nodular tissue could possibly be explored for differential diagnosis of TBNs and thyroid cancer.
Perceived Satisfaction of Public Health Facilities’ with the Quality of Logistics Service Provided by Pharmaceutical Fund and Supply Agency Bahirdar Hub, Northwest Ethiopia: Descriptive Study
Authors: Bahiru Tefera Bereket
Published: June 2023

Aim: This study aimed to investigate the satisfaction of public health facilities in the quality of logistics services received from the Pharmaceutical Fund and Supply Agency Bahirdar hub. Methodology: A descriptive research design has been used for assessing satisfaction. The data collection was carried out from 28 April/20, 2019 to – 20 June/2019. All hospitals in the study area were selected purposively and simple random sampling with a lottery method was used to pick health centers from the sampling frame. A total of 64 participants were selected for data collection. Epidata software and SPSS version 20 were used for data entry and analysis, respectively. Frequency distribution, arithmetic means, and percentages were calculated. Result: All questionaries were successfully filled and returned. It discovered that 41(64.1%) of respondents were neither satisfied nor dissatisfied, while 19(29.7%) considered themselves as ‘satisfied’ with the overall quality of the logistics services they received. Besides, 3(4.7%) of the respondents said they were ‘dissatisfied’ with the service and 1(1.6%) was highly dissatisfied with the service. From all dimensions, the condition of pharmaceutical delivery and product availability received the highest (3.749) and the lowest mean score (2.885), respectively. Conclusion: The overall perceived satisfaction of public health facilities with the quality of logistics service given by the Pharmaceutical Fund and Supply Agency Bahirdar hub was in the middle of the continuum, with the mean score close to the 5-Likert scale midpoint.
Novel Vesicular Drug Delivery Systems Proniosomes
Authors: Gandla Kumaraswamy
Published: June 2023

These proniosomes, which are dry surfactant-coated particles that form niosomal dispersion in hot aqueous fluids immediately on stirring, are the subject of this review paper. It is easier to transport, distribute, store, and administer dosage forms such as proniosomes thanks to their provesicular structure, which reduces the issues of vesicular system physical stability such as aggregation, fusion, and leakage. Lipophilic or amphipilic medications can be delivered effectively by oral route using proniosome powders, which are suitable dosage forms. Proniosome preparation, characterisation, release profile, applications, advantages, and downsides are all discussed in this review in great detail.
PERMINTAAN MAAF NEGARA ATAS PELANGGARAN HAM YANG BERAT SEBAGAI BENTUK REPARASI KORBAN
Authors: Maria Kunti Atika Putri  , Abdul Munif Ashri  , Ch. Idzan Falaqi Harmer  , Dita Gusnawati  , Weldayanti Saputri
Published: June 2023

The settlement of gross violations of human rights cases in Indonesia has faced various obstacles, including the absence of a public state apology. In fact, according to International human rights normative standards, an apology is categorized as an effective form of reparation. By a socio-legal research approach, this article examines the significance of a public state apology from the perspective of victimology and International human rights standards, as well as the victim's perspective. Interviews were also conducted with victims of the gross violations of human rights in the 1965-1966 tragedy and the tragedy of Semanggi I in 1998. This article argues that according to the perspective of radical victimology, an apology is a form of state intervention in the form of symbolic recovery. Based on Boven/Bassiouni Principles, the public state apology is acknowledged as 'Satisfaction' for the victim. Even though some victims tend to reject the public state apology, this article argues that this symbolic reparation should be the first step in fulfilling reparations for victims. An apology should also be accompanied by other forms of reparation, such as the prosecution of the perpetrators of gross human rights violations at the Human Rights Court.
PERLINDUNGAN INVESTOR ASING DARI RISIKO SENGKETA MELALUI ARBITRASE SEBAGAI FORUM PENYELESAIAN SENGKETA INVESTASI
Authors: Eunike Pebria Purba
Published: June 2023

In terms of investing in a country, one of the considerations of investors is related to the risk of disputes. This consideration is crucial, considering that the main goal of investors investing in a country is to make a profit. Based on these facts, a legal issue was found regarding what Indonesian legal instruments were formed to provide legal protection to foreign investors from the risk of disputes and how Arbitration as an Investment Dispute Resolution Forum provides legal protection to investors from the risk of disputes. The purpose of this research is to find out Indonesian legal instruments related to legal protection for foreign investors from the risk of disputes, and to find out the efficiency and effectiveness of arbitration as an investment dispute resolution forum in providing legal protection for foreign investors from the risk of disputes. This research uses normative juridical research methods. The conclusion of this study is that there are several juridical factors underlying the statement that arbitration arrangements in Indonesia have not been able to fully provide legal protection for foreign investors, including Indonesia is considered a country that is not friendly to foreign arbitral awards because it is considered easy to refuse the implementation of foreign arbitral awards with applying the principles of the State Act Doctrine which places State Owned Enterprise as a state that cannot be sued, the problem of choosing a forum due to arrangements that tend to favor one party, and there is a legal vacuum related to the time period for registering international arbitration. Arbitration in providing legal protection for foreign investors from the risk of foreign investment disputes in Indonesia by prioritizing the main matters in the form of the superiority of arbitration in the system, implementation, effectiveness and efficiency of the arbitration process, and the final arbitral award.
Mediating Role of Work Engagement and Trust in Leadership: The Influence of Transformational Leadership on Championing Behavior
Authors: Dinda Rizka Karunia , Wahyuni Salamah
Published: June 2023

This article aims to explain the effect of transformational leadership on championing behavior with work engagement and trust in leadership as mediators. A literature review is conducted to determine the variables that build the conceptual model. The expected findings are a positive relationship between transformational leadership and championing behavior, as well as the mediating role of work engagement and trust in leadership. This study explains whether the presence of championing behavior will make employees want to be invited to change during the period of organizational change. This study provides an alternative conceptual model in the field of human resources, especially employee behavior. Researchers hope that this research can provide an understanding of the importance of championing behavior to employees and organizations when organizational change occurs. This paper is also expected to contribute theoretically, practically, and may be used for future studies.
The Role of Job Satisfaction Mediates the Effect of Compensation with Employee Loyalty at Senetan Villas & Spa Resort
Authors: Kencana Ida Bagus Megawisnu , Surya Ida Bagus Ketut
Published: June 2023

This research was conducted at Senetan Villas & Spa Resort which is one of the companies engaged in accommodation or lodging services. This paper providing perspective of the role of job satisfaction as mediator at compensation and employee loyalty. The sample used in this study was 60 people. Data collection extracted from distributing questionnaires. Analysis of the data in this study using path analysis. The results show that compensation has positive significant effect on job satisfaction and loyalty and job satisfaction strengthen compensation at employee loyalty.
The Reasons for Permission to Marry Ahlul Kitāb Women in the View of Sayyid Sabiq
Authors: Munir Akmal Abdul , Mochammad Sahid Mualimin , Zulkifli Zulkifli , Fauzi Ahmad
Published: June 2023

Marrying women from the people of the Book (ahlul kitāb) is a matter of dispute amongMuslim scholars, some allow it and some forbid it. Sayyid Sabiq is among the scholars who allows Muslim men to marry women of the People of the Book under strict requirements to avoid harm and negative impacts that will occur if the marriage is carried out. This paper discusses the law of Muslim men marrying women of ahlul kitāb (the People of the Book)and analyzes it from the perspective of Sayyid Sabiq. Based on the results of the study conducted, the authors found the fact that SayyidSabiq allowed Muslim men to marry ahlul kitābwomen based on the following considerations: (i) To eliminate barriers between ahlul kitāband Muslims. (ii) As a means to establish social relations and closeness between others so that they can provide space for non-Muslims to learn and know the truth of Islamic teachings. (iii) As a means to invite them to follow Islam
The Implementation of Dharuriyat Concept by Muslims Traders in The Pemangkat Market of Sambas Regency.
Authors: Arifin Zarul
Published: June 2023

This study aims to determine the application of the Dharûriyâ concept among Muslim food traders at Pemangkat Market, Kambas Regency. This research is qualitative descriptive using a socio-religious approach. Data were obtained through observations and interviews with shop owners/grocers of Muslims at the locations which were then analyzed using inductive analysis techniques. This study concludes that the majority of Muslim traders in Pemangkat Market have applied five aspects of the Dharûriyât concept, namely: (i) Hifz al-Din (maintaining religion), which is marked by their obedience in carrying out worship, (ii) Hifz an-Nafs (maintaining the soul), their patience to avoid conflicts between fellow traders, (iii) Hifz al-Aql (maintaining reason), which is characterized by the tendency of traders not to consume/sell liquor; (iv) Hifz al-Mal (maintaining wealth), which is indicated by a penchant for saving/investing and spending their wealth in the way of goodness; (v) and Hifz an-Nasl (maintaining offspring) which is shown by the enthusiasm of the actors to provide good education to children and feed them from lawful assets.
'Iddah in the View of Islam and Feminists
Authors: Hilal Syamsul , Harahap Sumper Mulia
Published: June 2023

This study examines Islamic concepts of 'Iddah (waiting period for a divorced wife) and how the Feminists view it. The aim is to comprehend the different perspectives and try to put the problem in the right position. This research is purely library research using a socio-philosophical approach. Data were obtained from literature, books, and available documents. Based on the results of the study, it can be concluded that in Islamic teachings 'iddah is intended to determine the status of the womb, whether pregnant or not, to avoid mixing the lineage of the expecting baby. This is different from the view of the feminists who think that the provision regarding 'iddah is a product of a patriarchal culture that marginalizes women as it only applies to women, and not to men. This feminist view is based on the spirit of equality before the law which demands equal rights and obligations. The view, however, needs to be reviewed as the provision of 'iddah does not necessarily mean ignoring the principle of equality between men and women. Men and women by nature are created with different physical and emotional characters according to their respective roles. Even if such a view is applied, new problems will arise and damage the order of human culture universally
The Implementation of The Concept of Maslahat (Benefits) in Determining The Minimum Age of Marriage in Islamic Family Law in Indonesia and Jordan
Authors: Bunyamin Mahmudin
Published: June 2023

This study examines the development of Islamic Family Law (al-Ahwāl al-Syakhshiyah) in modern Islamic countries, especially in Indonesia and Jordan. The aim is to gain a deep understanding of the phenomenon which has become a new strategic way to accommodate the idea of Islamic law reform into a more actual form. This research is descriptive-qualitative literature research. Qualitative research is a research procedure that produces descriptive data in the form of written speech, and observed behavior of research subjects. This study finds the fact that the concept of maslahat applied in marriage law in Indonesia and Jordan aims to achieve the general benefit, reject harm, preserve laws or regulations that have been in effect and are considered good, and develop them following Islamic law and the values of local wisdom that become characteristics of each country. Viewed from the other side, the phenomenon of family law reform that is developing in several Muslim countries today can be seen as the beginning of the process of transitioning fiqh law to positive law which is manifested in the form of national legislation.
Hajj, Istita'ah, and Waiting List Regulation in Indonesia
Authors: Huda Qomarul , Haeba Ilham Dwitama
Published: June 2023

This study examines the concept of istita'ah (capability), and the problems faced by pilgrims in Indonesia with the departure regulation that implements a waiting list system. This research is purely a literature study using a normative juridical approach. Islamic law stipulates that one of the conditions that must be met by someone who will perform the pilgrimage is istita'ah (capable) which includes aspects of physical and spiritual health, financial ability, and safe situation. Unfortunately, even though these conditions have been met, it does not necessarily allow someone to go directly to Mecca to perform the pilgrimage. The reason is that there is a quota system set by the Saudi Arabian Government to balance the coming pilgrims with the capacity of the holy cities of Mecca and Medina. As a result of this quota system, prospective pilgrims in Indonesia have to queue waiting for departure, with a waiting time span of tens of years. This study finds out that the waiting list system, although aimed at ensuring the smooth and comfortable in performing pilgrimage, turned out to be an obstacle, because there is no guarantee that a person, in such a long waiting period, will remain healthy, even many. some of them had died before the time of departure arrived. Therefore, the government must find a solution to suppress the waiting list so that it does not continue to extend, by setting certain criteria for individuals who will register, for example the age limit and whether or not the person has performed hajj before.
Legal Conflict in Zakat Management in the Prismatic Communities of Kapuas Regency, Central of Kalimantan
Authors: Masrawan Masrawan , Anshari A. Hafiz , Hakim Budi Rahmat , Syaikhu Syaikhu
Published: June 2023

Abstract: Legal Conflict in Zakat Management in the Prismatic Communities of Kapuas Regency, Central of Kalimantan. This study is aimed at analyzing the legal conflict in the management of zakat (charity) among prismatic communities in Kapuas Regency, Central of Kalimantan. This intersection occurs between Islamic law relating to the management of zakat and the tradition, or customary law held by the local community. This phenomenon gives rise to poly normativism (legal overlap) between formal rules and living traditions in the local community. This research is empirical-normative in nature, using a combination of several approaches, i.e., the empirical, historical, normative, and conceptual approaches. The data were obtained through interviews, documentation, and direct observation of zakat management institutions and community behavior supported by the tradition of local society. The results of the study indicate that there is an intersection between the rules used in the management of zakat and the customary laws that live in a prismatic society in Kapuas Regency. For this reason, it is necessary to make adjustments in the regulation of zakat management while raising public awareness of the importance of optimizing zakat to support the interests of the state, in general, and in particular, for the interests of the local Muslims themselves.
The Shortest and Longest Pregnancy Period According to Fiqh and Legislation of Muslim Countries
Authors: Trigiyatno Ali
Published: June 2023

The Shortest and Longest Pregnancy According to Islamic Jurisprudence and Legislation of Muslim Countries. This study examines how long a woman's pregnancy takes according to fiqh Islamic Jurisprudence and legal provisions in several Muslim countries. This research is purely a literature study using a normative approach that refers to the provisions of family law in several Muslim countries. The legal analysis used is an authentic and doctrinal interpretation method. The fiqh scholars state that the shortest gestation period is six months, while the fiqh scholars differ in their opinion regarding the longest gestation period. Generally, they agree that the longest gestational age is six months. Although legal provisions in various Muslim countries often do not refer to the opinion of fiqh scholars who argue that the longest gestation period is more than one year. This research finds the fact that legislators in various Muslim countries do not use the classical scholar's opinion about pregnancy because it is considered unscientific and does not support social reality. Muslim countries generally define six months as the shortest period of pregnancy and one year as the longest, except for Brunei Darussalam which defines four years.
The Role of Masturah Da'wah in Forming a Sakinah Family in The Jamaat Tablighi of Manado City
Authors: Bilalu Naskur , Purwadi Wira , Subeitan Syahrul Mubarak
Published: June 2023

This paper discusses the formation of the sakinah family through the role of da'wah Masturah, a Jamaat Tablighi's program, namely da'wah efforts among women. Because the task of reviving religion lies not only on men but also on women, a sakinah family will be formed when every family member is obedient to Allah SWT. This study aims to determine the role of da'wah Masturah in forming a sakinah family in Jama'ah Tablighin Singkil District, Manado City. This research is field research with a qualitative nature whose data is collected through observation, interviews, and documentation related to the focus of research on the Jama'ah Tablighin Singkil District, Manado City. The results of this study show that da'wah Masturah is very influential in forming a sakinah family in Jama'ah Tabligh in Singkil District, Manado City. There are 3 (three) indicators that da'wah Masturah plays an important role in forming a sakinah family: First, every family member is obedient in carrying out religious orders; Second, husband and wife understand their rights and obligations; and; Third, children are expected to be a pious and/or pious generation
Legal Protection for Children Out of Wedlock: Ensuring the Best Interests of Children Through Judge Decisions
Authors: Rohmawati Rohmawati , Siddik Syahril
Published: June 2023

This article examines the protection of the rights of children out of wedlock in the Religious Courts. The ambiguity of the concept of the best interests of the child has prompted judges to interpret this concept to realize legal protection for children out of wedlock. This study reveals the application of the principle of best interests for children by Religious Court judges in protecting children out of wedlock. This study uses a case approach and legal philosophy. The results of this study indicate that the Religious Courts, in determining the origin of children, generally protect the rights of children out of wedlock proportionally. In the best interests of the child, the judges grant recognition of the child and provide a limited legal relationship for an illegitimate child with his biological father. The existence of this legal relationship has provided legal certainty regarding the status of children out of wedlock as biological children of both parents; so that the children have human dignity (hifẓ al-‘irḍ). In addition, judges have realized distributive justice that provides benefits for children out of wedlock, without ignoring the norms of Islamic law regarding the purity of lineage, through the granting of living rights for the survival of children (hifẓ al-nafs), spiritual development (hifẓ al-din), education a proper will (hifẓ al-'aql), and a mandatory will from his father (hifẓ al-māl).
Husein Muhammad’s Thoughts on Gender Equality in Islamic Inheritance Law
Authors: Firdawaty Linda , Munji Ahmad , Sukandi Ahmad , Bukhari Nurnazli , Apriani Ira
Published: June 2023

This research aims to analyze the philosophical reasons for Husein Muhammad's thoughts about the importance of the equal distribution of inheritance between men and women in Islamic inheritance law, as well as the method of legal reform that he uses when understanding verses about inheritance. This research is field research. Data was collected through virtual interviews. Data analysis was descriptive qualitative, with maslahah theory, and historical and sociological approaches. The research findings show that one of the reasons why verses about inheritance need to be reinterpreted, according to Husein, is because these verses fall into the category of mutashabihat verses (interpretable) so they need to be reinterpreted by looking at the current context. Another reason is that the inheritance verses that regulate section 2:1 for men and women in the Prophet's era were only intended for the context of society at that time, where women had no inheritance rights, and even women were used as objects of inheritance. Nowadays, the existence of women is growing. That way the portion of their inheritance should be reformed and adapted to current socio-cultural developments. Husein emphasized that gender bias occurs due to bias when interpreting the Qur’an, and the influence of patriarchal culture.
Tahlil Marriage Among the Sasak Tribe of Lombok Based on Maqashid Al-Shari’ah Perspective and Its Relevance to Compilation of Islamic Law
Authors: Arifin H. Munir Zainal , Nurul Wathoni Lalu Muhammad , Bin Mujib Lalu Supriadi , Dahri Harapandi
Published: June 2023

This study examines the practice of Tahlil Marriage carried out in several sub-districts in East Lombok Regency. Tahlil marriage or Cine Bute or muhallil is carried out as a condition that reconciliation between ex-husband and ex-wife who has been divorced is permissible. Tahlil Marriage (Cine Bute) in the Sasak community is carried out secretly without authorization from the Office of Religious Affairs. This research is classified as qualitative research with an empirical normative approach. Data were collected using observation, interview and documentation techniques and were analyzed through the perspective of Maqasid al-Shari’ah and Compilation of Islamic Law (KHI). This research found that Tahlil marriage in East Lombok Regency was divided into three forms: common marriages, contractual marriages, and common marriages initiated by contract marriages. In the view of Maqasid al-Shari'ah, the Tahlil marriages carried out by the Sasak tribe do not fulfill the aspects of dharuriyya, hajjiyat and tahsiniyyat. Among the factors that influence the Tahlil marriages performed by the Sasak tribe are the ease of divorce, the lack of public legal awareness, the low level of public education, the lack of understanding of religion and the weakness of law enforcement.
Smart Technology in Construction Industry: Opportunity during COVID-19 Pandemic
Authors: Fatimah Putri , Sodri Ahyahudin , Hamzah Udi Syahnoedi
Published: June 2023

The construction industry is a sector that plays an essential role in economic growth. The COVID-19 pandemic is an uncertain situation that significantly affects humans and industries, including the construction industry. The operational construction projects are complex with various activities and involve a large of workers. Prevention of the spread of COVID-19 that changes lifestyles and improves technology adoption. This study examines the relationship between increased technology adoption and limited workers’ social interaction in construction projects during the pandemic. A questionnaire survey was conducted to construction workers in DKI Jakarta, 74 valid responses were collected and correlation analyses were performed with SPSS version 28. The result of this study indicated a significant and positive correlation between increased technology adoption and limited workers’ social interaction in a construction project during the pandemic. There are opportunities for the construction industry to implement a digital transformation, Building Information Modelling (BIM), and intelligence visualization technologies to cope with the impact of the COVID-19 pandemic on construction activities. This study provides evidence that smart technologies application has a significant role in supporting the construction industry to mitigate the impact of the COVID-19 pandemic and opportunities for continuous improvement towards post-pandemic.
Rfid Application For Designing Lowcost Learning Device For Play And Learning To Read Early Braille For Blind Children
Authors: Bintari Bertha
Published: June 2023

It is very important for children who have low vision or visual impairment to be able to recognize braille letters and recognize words. This ability will help them to be able to read and write Braille. Braille recognition learning methods currently use technology as a learning aid or assistive device. However, assistive devices with this technology are still rare and unaffordable for some schools and students in Indonesia. The design of this braille learning aid applies RFID as a low-cost solution for learning braille reading aids. This tool integrates several braille learning methods that have been carried out by teachers when teaching braille recognition in schools. The integrated methods are the Mangold method, the Fernald method, the Flashcards method and the scrabble method. This tool helps children recognize braille letters, arrange them as words and is confirmed directly by the tool through sound if the letters arranged as a word are right or wrong. With this integration method, children are expected to be able to learn to read braille while playing, and learn independently.
Classification Of Lung and Colon Cancer Histopathological Images Using Convolutional Neural Network (CNN) Method An A Pre-Trained Models
Authors: Qasthari Brilly Lutfan , Susanti Erma , Sholeh Muhammad
Published: June 2023

Cancer is a severe illness that can affect many young and older people. In Indonesia, lung cancer is the leading cause of cancer-related death, whereas colon cancer, with more than 1.8 million cases worldwide in 2018, is the third most common cancer. This study intends to create a model to categorize histological images of lung and colon cancer into five labels to aid medical professionals' categorization job. This study uses a pre-trained model idea known as VGG19 in its CNN (Convolutional Neural Network) technique. The dataset uses 25,000 histological graphic pictures with a ratio of 80% training data and 20% testing data. The classification system for lung and colon cancer contains five categories: lung benign tissue, lung adenocarcinoma, lung squamous cell carcinoma, colon adenocarcinoma, and colon benign tissue. The training result revealed a 99.96% accuracy rate and a 1.5% loss rate. The model can be rated as excellent based on these results
EMAS SUMBER ZAKAT HARTA: PENELITIAN TERHADAP PELAKSANAAN KUTIPAN DI MALAYSIA
Authors:   Center of Islamic Philanthropy and Social Finance (CIPSF), Universiti Teknologi MARA Melaka, Saro Noraini , Nordin Rawi ,   Center of Islamic Philanthropy and Social Finance (CIPSF), Universiti Teknologi MARA Melaka
Published: June 2023

Emas sering disinonimkan dengan golongan wanita dan aset ini mempunyai nilai yang begitu berharga serta mendapat perhatian kalangan masyarakat. Sepanjang ketamadunan awal islam, emas merupakan barangan yang nilai tinggi selain perak bagi pertukaran iaitu dikenali sebagai sistem barter untuk mendapatkan sesuatu barangan lain yang diperlukan.Oleh kerana nilai emas yang tinggi , ia turut ditempa sebagai barangan emas perhiasan untuk golongan wanita seperti, cincin,gelang ,rantai dan lain-lain. Pemilikan emas kini menjadi trend dalam kalangan masyarakat yang mana ia emas ini dijadikan aset yang sangat bernilai berbanding membuat simpanan berbentuk mata wang. Oleh kerana ianya berharga dan bernilainya status emas ini maka menjadi satu kewajipan bagi mereka yang memiliki emas dan memenuhi syarat bertanggungjawab melaksanakan kutipan bagi maksud tersebut. Justeru itu,kajian ini akan melihat amalan kutipan zakat emas yang dilaksanakan di institusi zakat Malaysia. Kertas ini berbentuk empirikal di mana ianya akan melihat turun naik bagi jumlah kutipan zakat emas dari tahun ke tahun di institusi-instusi zakat yang terpilih. Kertas ini dapat membantu institusi-institusi zakat meningkatkan dan mengekalkan kutipan zakat emas dari semasa ke semasa. Kata Kunci : Sumber, Institusi, Zakat, Emas dan Kutipan
ADRESSING HOUSEHOLD WELLBEING THROUGH MAQASID SHARIAH: A MICRO PERSPECTIVE
Authors:   Center of Islamic Philanthropy and Social Finance (CIPSF), Universiti Teknologi MARA Melaka, Tuan Sayed Amran Sharifah Adlina , Abdul Rasool Mohamed Saladin ,   Center of Islamic Philanthropy and Social Finance (CIPSF), Universiti Teknologi MARA Melaka, Ali Siti Mariam ,   Center of Islamic Philanthropy and Social Finance (CIPSF), Universiti Teknologi MARA Melaka
Published: June 2023

Wellbeing is defined as a situation of positive feeling (happiness and satisfaction) and positive functioning elements (engagement and self-acceptance). Recent studies have shown wellbeing is conceptualized in a multidimensional form, explained in both objective and subjective perspective. From an Islamic perspective, wellbeing is explained through inside and outer fulfillment, driving towards a peaceful life, named as Hayat-e-Tayyaba. The objective of the vision of wellbeing is to satisfy the material and non-material needs. The maqasid al shariah principles are normally used by scholars to explain wellbeing in the Islamic perspective. The objective of this empirical paper is to present Islamic Household wellbeing Index (IHWI) using the five dimensions of maqasid al shariah. The present study employs 35 experts in identifying the five dimensions and the variables of the IHWI. The formulation of the IHWI is deliberated and its interpretation is highlighted. Keywords: Wellbeing, Maqasid al-shariah, micro
THE INFLUENTIAL FACTORS OF THE HERITAGE SHOPHOUSES’ ARCHITECTURAL DESIGN IN URBAN HISTORIC DISTRICTS IN MALAYSIA: A REVIEW
Authors:   Faculty of Built Environment and Surveying, Universiti Teknologi Malaysia, UTM Skudai, 81310, Johor Malaysia, Hakim Zamri Mohd Amirul , Abdul Majid Roshida ,   Faculty of Built Environment and Surveying, Universiti Teknologi Malaysia, UTM Skudai, 81310, Johor Malaysia, Rasyidi Mohd Hisyam ,   Faculty of Built Environment and Surveying, Universiti Teknologi Malaysia, UTM Skudai, 81310, Johor Malaysia
Published: June 2023

Heritage shophouses are the primary architectural legacy that has greatly characterised the place identity of the urban historic district in Malaysia since the 17th century through its distinctive architectural design character. In contrast to the modern building design that is seen as contextually isolated from the place identity of the urban historic district, the architectural identity of heritage shophouses is seen as successful in fitting into the place identity due to its significantly responsive architectural identity to contextual factors. This paper aims to systematically review the influential factors on the Malaysian heritage shophouse design which constitutes its architectural identity through content analysis. This paper extracts scholars’ studies on heritage shophouse architectural design features, heritage shophouse morpho-typologies, and the factors that influence its architectural identity development. Heritage shophouses in Malaysia are morphologically categorized into Early Heritage Shophouse styles, Eclectic Heritage Shophouses, and Non-Cultural Heritage Shophouse styles. Regardless of their architectural styles, all heritage shophouses are characterized by the façade articulation, the interior design including the spatial organization system, and the building construction materials. Every element is primarily influenced by the tropical topographical climates and material sources as a basic architectural adaptation, the building development standards set by the colonial regimes, cultural assimilation, and the advancement of building construction and materials. The findings of this study can help architects how to prioritize design considerations in developing their new architectural intervention design ideas in the urban historic district to preserve its valuable historical characteristics.
THERMAL AND DAYLIGHTING PERFORMANCE OF TRANSPARENT CONCRETE IN PENANG, MALAYSIA
Authors:   School of Housing, Building and Planning, Universiti Sains Malaysia, Penang, Malaysia, Vasudevan Karthikgheyan , Basher Hazril Sherney ,   School of Housing, Building and Planning, Universiti Sains Malaysia, Penang, Malaysia, Mohd Isa Mohd Hafizal ,   School of Housing, Building and Planning, Universiti Sains Malaysia, Penang, Malaysia
Published: June 2023

Modern technology studies and research developments have enhanced the quality and innovation of concrete. Transparent concrete is concrete that has light-transmitting properties which transmit light through the optical fibre. Optical fibres are reinforced in the conventional concrete mixture from one face to another face, which allows direct light to transmit through it. Daylighting factor is one of the fundamental qualities of the energy efficiency of a building. The thermal performance is also crucial to providing comfort to the building occupants. The literature studies cover the light transmittance and thermal performance of transparent concrete. Selected literature studies are reviewed based on the related topic, Asian countries, and countries with a similar climate to Malaysia. This research applies quantitative method where it was focus on experimental study to transparent concrete. The overall result indicates improvement on light transmission and thermal performance as the plastic optical fibre increased compared to conventional concrete. The total average outdoor surface temperature of transparent concrete shows a difference of 0.989°C lower than conventional concrete. The total average temperature different between conventional concrete and transparent concrete (560 optical fibre) are 0.9°C. This experiment's significant contribution is that using more plastic fibre optic reduces thermal conductivity and heat gain while allowing for greater daylighting. Finally, transparent concrete shows effectiveness on light transmission and thermal resistance where it can contribute to building industry on green building and sustainable design. However, the further studies on thermal performance with longer duration is required to analyses the thermal heat loss.