bluuebunny/crossref_metadata_2025 huggingface dataset:
Benefit of Serum Thymidine Kinase 1 Concentration for Risk Assessment from Gastric Neoplasms Progression to Carcinomas: A Systematic Review and Meta-analysis
Authors: Hei Ailian , Ma Hongbo , Li Maogang , Li Jin , Zhou Ji , He Ellen , Skog Sven
Published: May 2022

Background: Human Thymidine kinase 1 (hTK1), a key enzyme involved in the DNA synthesis during S-phase of the cell cycle and upregulation of cell proliferation, thus it is reliable tumor proliferating biomarker for assessment of tumor proliferation rate in serum and in tissue in oncology. This meta-analysis is investigation whether the serum TK1 concentration（STK1p）based on hTK1-IgY-polyclonal-antibody can provide a benefit for risk assessment from gastric neoplasm progression to gastric carcinoma (GC) as well as for evaluation of treatment effect in GC. 1.2. Methods: Relevant studies were identified from the following electronic databases: PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang, the Chongqing VIP Chinese Science and Technology Periodical Database and Chinese Biomedical Literature Database from May 1, 2008, until November 30, 2021. Study quality was evaluated by the modified Newcastle-Ottawa Scale. Pooled estimates of weighted mean difference (MD), sensitivity analyses and publication bias were evaluated using Review manager and STATA software. RESULTS: Twenty-seven studies included to 1,909 GCs and 1,229 neoplasms (superficial gastritis, chronic gastritis, atrophic and gastric ulcers) and 2,260 tumor-frees. The results showed that STK1p levels increased significantly in the following manner (P<.0.006): tumor-free < superficial gastritis < chronic gastritis < atrophic gastritis < gastric ulcer < GC. The STK1p value of the GCs one-month-post-surgery decline significantly by 66% compared to pre-surgery. 1.3. Conclusion: STK1p value has the potential to be an early risk warning indicator for early gastric neoplasms progression to GCs and to be a helpful index for monitoring the response to surgery. 1.4. Core Tip: In spite of improvements in diagnosis and treatment the long-term survival rate for a large number of GCs is still dismal. Hence, it is important to explore serum biomarkers for early prediction of risk gastric neoplasms into GCs. In this meta-analysis, the STK1p as a prognostic biomarker was investigated showed significantly higher in GCs compere to different neoplasm and tumor-free people and was significantly reduced one-month post-surgery. It demonstrates that STK1p as tumor proliferating serum-biomarker, can be not only used for early risk gastric neoplasm progression and evaluation of treatment effect in GC patients, but also for a variety of other tumor types in clinical setting.
Effectiveness of Early Suckling on Third Stage Labour among Parturient Women at Government Ranees Hospital, Pudukkottai
Authors: Sumithra S  , Radha C  , Mangai S
Published: May 2022

The present study was conducted to evaluate the effectiveness of early suckling on third stage of labour among parturient women at Government Ranees Hospital, Pudukkottai, for that the posttest only control design was used. 120 parturient women in third stage of labour was selected by using probability simple random sampling. Data was collected with the tools including structured observation record for observing duration and amount of blood loss; standardised Latch score and maternal satisfaction rating scale. Tools like descriptive statistics and inferential statistics such as unpaired “t” test and chi-square test, hypothesis were also used. Latch score was assessed using standardised rating scale and maternal satisfaction score was also assessed using rating scale. The study revealed that early suckling was effective in reducing the duration of third stage of labour and blood loss and there was a significant association between duration of third stage of labour and blood loss among parturient women in experimental group with their selected demographic variables the Latch score and maternal satisfaction score was also found to be 100 percent among experimental group. It is concluded that early suckling was the most safe and most effective intervention during third stage of labour and it can naturally release the oxytocin to stimulate the uterine contraction and it helps to reduce duration of third stage of labour and amount of blood loss and increase the maternal infant bonding
Male Nurses' Attitude as a Nursing Professional and Attitude of Female Colleagues Towards Male Nurses, at AIIMS, New Delhi
Authors: Murry L. Levis , Tirwa Milan , Das Smita , Devi Yumnam Surbala , TK Ajesh , Chandelia Kamlesh
Published: May 2022

The study aimed to assess the male nurses’ attitude as a nursing professional, and attitude of female colleagues towards male nurses. A cross sectional survey of Nurses (including both male and female nurses) was done in a 1500-bedded teaching hospital in North India. Male and female nurses who have at least 2 years of working experience in nursing were recruited. The total participants were 69 male nurses selected by simple random sampling and 132 female nurses selected by convenience sampling. A self-developed 5-point Likert scale was used to assess attitude of male nurses towards nursing profession, which had 16 items and 12 items for the female nurses’ attitude towards male nurses. The attitude towards nursing was overwhelmingly positive with 70 percent (male nurses) and 67.4 percent (female nurses working with male colleague) of them having “positive” attitude, 25 percent (male nurses) and 22.7 percent (female nurses working with male colleague) having “very positive” attitude. None of them had a negative attitude towards the profession. Chi square test showed no significant association. To conclude, male nurses are comfortable in the profession and have a healthy attitude towards their profession. Majority of the female nurse colleagues were comfortable working with the male nurses and most of them believed that men in nursing have brought a positive change in the profession.
Knowledge of Transmission of HIV/AIDS from Mother to Child Among Pregnant Women
Authors: Mala LC , G Momin Henalish , Holisema  , Marbaniang Ibapynbiang , K Lalramluahpuii  , Sajida Kh , Kipgen Kimchong
Published: May 2022

Mother-to-child transmission (MTCT) of HIV is the spread of HIV infection from women with HIV to her child either during pregnancy, childbirth or breastfeeding. Pregnant women with HIV who have knowledge and awareness, receive anti-retroviral therapy (ART) during pregnancy and childbirth to prevent occurrence of MTCT of HIV during delivery, to reduce the risk of infection. The present study sought to assess the knowledge of transmission of HIV from mother to child among 200 selected mothers attending the Gynae OPD of RIMS Hospital, Imphal (Manipur). Data was collected from 24 May to 2 June 2018 (10 days). The study brought out that educational status of mother is associated with knowledge of MTCT of HIV/AIDS, so that nurses and other health care functionaries should be actively engaged in imparting relevant health education.
Efficacy of Dietary Supplementation in the Form of Multigrain Panjiri in Managing Anaemia among Ethnic Tribal Women of Chhattisgarh
Authors: Barai Reena
Published: May 2022

As per the Government of India 2013 database, anaemia in India is a serious public health issue with a high prevalence of about 74 percent with haemoglobin< 11gm/dl. It’s prevalent in all age groups, nearly 58 percent in pregnant women, 50 percent among non-pregnant non-lactating women, 56 percent among adolescent girls. The situation is no different in Chhattisgarh. With a tag of tribal dominated state situation needs to be addressed carefully because of socio-economic status of tribal women is comparatively low. The present study assessed the efficacy of dietary supplementation in the form of multigrain panjiri in management of anaemia among ethnic tribal anaemic women of Chhattisgarh. In the study, 100 tribal women from tribal dominated region of Chhattisgarh were selected as sample. The age range of selected subjects was 19 to 25 years. The inclusion criteria for selection of subjects was WHO classification for anaemia. Cyanmet haemoglobin method was used for estimation of haemoglobin. Two groups were created with equal number of subjects in both the groups. The experimental group received dietary supplementation in the form of multigrain panjiri for three months while subjects belonging to control group were not supplemented the additional soya multigrain panjiri. Results reveal that after the study period, more percentage of selected tribal women from experimental group had normal haemoglobin levels as compared to their counterpart i.e. tribal women belonging to control group. It was concluded that soya multigrain panjiri when used as dietary supplement, is beneficial in increasing the haemoglobin levels and thereby useful in management of anaemia in tribal women.
Knowledge and Practices of Menstrual Hygiene among Adolescent Girls of Government Women College Parade, Jammu (J&K)
Authors: Kapoor Jyoti
Published: May 2022

Adolescence is a transition period from childhood to adulthood. In this period one of the major physiological changes that takes place in the adolescent girls is the onset of menstruation. Good menstrual hygiene is crucial for the health and dignity of girls and women. The present study was aimed to assess the knowledge and reported practices of menstrual hygiene among adolescent girls of selected Government College, Parade, Jammu (J&K). The sample consisted of 50 adolescent girls. Purposive sampling technique was used to select the sample. Socio-demographic profile and self-structured questionnaire was used to assess the level of knowledge and practice regarding menstrual hygiene among adolescent girls. The study concluded that the knowledge among adolescent girls was good and practices used them were satisfactory. There is need to increase knowledge regarding menstrual hygiene and make adolescents practice good hygiene habits to prevent various pelvic infections and diseases.
Design and Development of Solar Panel Cleaning Robot
Authors: Prof. Vijaya Avati  , Sohilkhan Pathan  , Akshay Nanaware  , Tushar Bhapkar  , Prasad Ranpise
Published: May 2022

Energy is one of the major issues that the we are facing in India, the supply of energy has been one of the major problems for both urban and rural household about 60% to 70% of the energy demand of the country is met by fuel wood and agriculture residues. Solar energy is a renewable source of energy, which has a great potential and it is radiated by the sun. Renewable energy is important to replace the using of electric energy generated by petroleum. Solar power has become a source of renewable energy and solar energy application should be enhanced. The solar PV modules are generally employed in dusty environments which are the case tropical countries like India. The dust gets accumulated on the front surface of the module and blocks the incident light from the sun. It reduces the power generation capacity of the module. The power output reduces as much as by 50% if the module is not cleaned for a month. The cleaning system has been designed cleans the module by controlling the Arduino programming. To remove the dust in the PV modules to improving the power efficiency.
Presupuesto, gasto social y estructura tributaria
Authors: El Editor
Published: May 2022

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ECA Estudios Centroamericanos, Vol. 50, No. 564, 1995: 993-997.
A DIFICULDADE DA RESSOCIALIZAÇÃO DENTRO DO SISTEMA PRISIONAL BRASILEIRO
Authors: Rodrigues Júlio César Santos , Moura Luciano Ricardo de
Published: May 2022

O presente artigo científico tem como principal questionamento o fato de que “como o atual sistema prisional brasileiro, as penitenciárias podem ser eficazes na ressocialização do indivíduo que está cumprindo a pena?”. É sabido que o sistema prisional brasileiro é tido como um dos campos inseridos na sociedade, onde é possível verificar que a segurança pública possui relação direta com tal instituto e está passando por situações delicadas. É notório que grande parte de indivíduos que praticam ilícitos penais são reincidentes, assim, fazendo com que viver temeroso pela ação de criminosos tornou-se rotina, não mais apenas em grandes centros urbanos, mas também em pequenas cidades e zona rural. Diante deste cenário, se faz necessário um estudo mais aprofundado acerca dos motivos que envolvem o cometimento de delitos e qual a eficácia do sistema prisional brasileiro perante a ressocialização do indivíduo. Sendo assim, o presente artigo trará as nuances, opiniões, jurisprudências, normas legais e fundamentos que possam delimitar e explicar os fatores determinantes da eficácia do sistema prisional brasileiro e a sua influência no campo da segurança pública.
“To Teach Empathy and Fight Racism”
Authors: El Mugammar Laila
Published: May 2022

“Fugitive libraries,” as described by Shannon Mattern in her titular work, are Black libraries that emerge in American contexts in response to conditions of exclusion and antiBlackness. The question of whether they are necessary in a Canadian cultural context has not been investigated before, in part due to the lack of distinct existing scholarship on Black Canadian librarianship. Using an interdisciplinary framework informed by Black Canadian and Indigenous scholars, I undertake a content analysis and close reading of Black History Month and Black Lives Matter programming and booklists in two Canadian public libraries from 2020-2021 to investigate whether the programming meets the needs of Black Canadian communities, and whether fugitive libraries are a necessary response. I determine that though clear efforts towards the inclusion of Black narratives are apparent in these libraries, Black History Month programming and the discourse surrounding it are shaped to benefit and mobilize non-Black Canadians, rather than to address the needs of particular Black communities, and propose fugitivity as a solution to these conditions.
OA isn’t free, it costs folks like you and me
Authors: Bryans John
Published: May 2022

Despite the framing of open access (OA) as a progressive movement that challenges neoliberalism and champions the public good, academic labour is often left out of these analyses (Eve, 2017). In a bid to liberate academic labour from the neoliberal hands of commercial publishing, advocates of OA have argued that making scholarly work “free” can help to establish an academic commons (de Rosnay, 2021). However initiatives to mandate OA in academia like “Plan S” set the stage for academic labourers to be compelled to give up rights to their intellectual property (Frantzvag & Stromme, 2019). In this essay I argue that the broad acceptance of OA as the liberatory savior of academic publishing is misguided, as it obscures the right-wing libertarian roots of the movement and would see academics voluntarily alienate themselves from their labour (Golumbia, 2016). Drawing on Golumbia’s (2016) Marxist reading of the political economy of OA, I argue that devaluing academic labour by characterizing it as unproductive and immaterial negates the abstract labour that produces scholarly works. Undoubtedly, libraries have an important role to play in the OA “revolution” (Burns, 2018), although not as assenting boosters but as critical voices that advocate for the rights of workers.
Capturing life - not death: A case for burying the posthumous parallax
Authors: Starck Nigel
Published: May 2022

Australian newspapers, in recent years, have increased significantly the column space devoted to obituaries. Style and quality are erratic, however. Syndicated pieces from specialist writers in Britain and the United States appear alongside homespun obituaries submitted for publication by surviving family members or friends. There is an apparent unwillingness, on the part of Australian editors, to encourage the writing of material which speaks critically of the dead. That reticence is at variance with emerging practice overseas, where there is frequently a concerted effort to ‘get nearer the character of the person … to delve behind the curriculum vitae and by Description and anecdote convey what the lamented - or unlamented - one was really like’ (Bowman 1997). This article compares publication styles and policies, and examines (on the basis of the author’s own experience) the challenges inherent in both the exercise and the teaching of the obituary art.
Constitutional boundaries of presidential power and general level of political culture. the case of Serbia
Authors:   Institute of Comparative Law, Belgrade, Serbia, Djordjevic Miroslav
Published: May 2022

The general level of democratic, political culture in one country is the important determinant that should be taken into consideration both when analyzing its constitutional order as well as when considering its future shaping and direction. Countries that have had a substantial discontinuity in their historical-democratic development face special challenges when returning to the paths of liberal-democratic constitutionality, perhaps the biggest of which is raising the general level of political culture and (re)building a constitutional, democratic tradition. During this process particular systematic distortions may occur, among others, those regarding the mutual control and influence of the highest state authorities. In the Republic of Serbia, there is a noticeable inconsistency in what is generally perceived by the general public (as well as by the constitutional law scholars) as the level of powers and the authority of the President of the Republic. Constitutional framework is often being interpreted without taking the wider scope of the problem into consideration, which includes the immaturity of the democratic culture. This leads to (apparent) inconsistency between the presidential powers by the Constitution and how they really manifest themselves in reality. In this paper the author analyses Serbian constitutional omissions in this regard and offers possible solutions
Achados clínicos do paciente com Osteonecrose dos Ossos Maxilares associada ao uso de Bisfosfonatos: uma Revisão Integrativa
Authors: Santos Leandro Quintino Vannutc Rocha , Melo Josy Larissa Pinheiro , Lopes-Filho Antônio Mont’Alverne
Published: May 2022

A osteonecrose dos maxilares associada a medicamentos (ONMM) pode ser definida como a presença de osso necrótico exposto, ou que pode ser explorado através de uma fístula, no território maxilofacial, mantido por um período mínimo de 8 semanas, sem histórico clínico de tratamento por radioterapia na área. O presente estudo buscou, mediante a realização de um estudo de revisão integrativa, a partir da busca de estudos de casos clínicos, descrever o perfil clínico do paciente diagnosticado com ONMM associado ao uso de bisfosfonatos. Foi possível identificar que há um número significativo de relatos de casos que demonstram o impacto da ocorrência de osteonecrose nos maxilares associados à medicamentos, especialmente os relacionados ao grupo dos bisfosfonatos. Além disto, destacou-se que o principal bisfosfonato associado à ocorrência de osteonecrose foi o Ácido Zoledrônico, seguido do Aledronato de Sódio, predominantemente utilizado para o tratamento de distintos tipos de doenças, tais como osteoporose e até mesmo câncer de próstata, e câncer de mama. Também foram identificados relatos que demonstram a importância clínica de avaliação de osteonecrose em pacientes com diagnóstico de osteoporose que faz uso de bisfosfonatos.
Clinical and anamnestical aspects of very early preterm birth
Authors: Mosendz Olena
Published: May 2022

The objective: determine risk factors, causes and clinical features of patients with very early preterm birth.
Materials and methods. The study analyzed the data of anamnesis, the course of pregnancy, childbirth and perinatal outcomes of 166 women of reproductive age with very early preterm birth at 22–27 weeks of gestation. The fact of childbirth at these stages of pregnancy is the main criterion of inclusion. The patients were divided into two groups depending on the criteria of live
birth: group 1 – 79 women, whose labor was regarded as late miscarriage (retrospective study); group 2 – 87 women, whose labor occurred as a very early preterm (prospective study). Exclusion criteria: congenital malformations of the fetus. Patients of both groups have got a comprehensive examination using clinical, instrumental and laboratory research methods. Results. During the management of pregnancy of patients of these groups, special attention was paid to the assessment of risk factors for the development of very early preterm labor, among which the main ones were urogenital infections (83,7% and 78,9% in groups 1 and 2, respectively), which caused perinatal mortality in both groups (p˂0,05). A combination of pathogens was found in almost half of the subjects (43% in group 1,44% in group 2). Patients of both groups had a serious general and obstetric anamnesis, high frequency of inflammatory processes of the genitals, surgery and hormonal disorders with diseases caused by them. The main complications
of gestation of pregnant women of both groups in the second trimester were the miscarriage risk (43% and 30%, respectively) and dysfunction of the fetoplacental complex (FPC) (22,7% and 21,8%, respectively), which caused the syndrome of delayed fetal development in both groups of subjects - in 66% and 63% of children, respectively.
Conclusion. Analysis of general and obstetric history, the presence of infectious factor in combination with extragenital pathology confirm the polyetiology of the causes that leads to very early preterm birth. Considering the main risk factors of preterm birth, a thorough examination for urogenital infections in women at the stage of pre-pregnancy and during pregnancy, followed by treatment and restoration of normal vaginal biocenosis, as well as study of fetoplacental system function from early pregnancy.
Preventive measures and timely treatment of fetoplacental disorders should promote prolonging pregnancy to longer gestations, which is the best way to improve perinatal outcomes.
Features of lipid peroxidation processes and antioxidant protection system in pregnant women with type I diabetes mellitus and their newborns
Authors: Тітоv Оlexandr , Senchuk Anatolii , Titova Victoria , Doskoch Inna , Chermak Volodymyr
Published: May 2022

The objective: to determine the characteristics of lipid peroxidation processes and the antioxidant defense system in pregnant women with type I diabetes mellitus and their newborns.
Materials and methods. 160 patients at 12–41 weeks of gestation were examined. The main group included 110 pregnant women with type I diabetes mellitus, the control group – 50 healthy pregnant patients. Evaluation of lipid peroxidation activity was determined by the content of diene conjugates, lipid hydroperoxide, malondialdehyde in blood serum and erythrocytes, superoxideanion O2 in blood plasma.
Results. Analysis of the results in patients with diabetes mellitus showed a significant activation of lipid peroxidation processes. In the first half of pregnancy, the content of lipid hydroperoxide, malondialdehyde of plasma and erythrocytes, as well as superoxide anion in patients with diabetes mellitus was higher than in healthy pregnant women. In the second half, all lipid peroxidation
indicators in patients with diabetes mellitus exceeded the corresponding indicators in healthy pregnant women.
The dynamics of antioxidant defense system indices in diabetes mellitus indicates a compensatory tension of its main links with a subsequent decrease in their activity, in contrast to healthy pregnant women, where the antioxidant defense system activity increases adequately to the growth of lipid peroxidation activity.
Conclusion. Disorders in the lipid peroxidation system in pregnant women with diabetes mellitus should be regarded as such that negatively affect the development and functioning of the fetoplacental complex. The results indicate the need to include the pregnant women with diabetes mellitus in the risk group of the placental dysfunction development, with the aim of its timely
prevention, thereby reducing perninatal morbidity and mortality.
Features of violations of menstrual and genesial function at combined pathology of uterus
Authors: Gladenko Svitlana
Published: May 2022

The objective: study of nosotropic aspects of violations of menstrual and genesial function at combined pathology of uterus.
Materials and methods. For the decision of the put purpose we conducted a complex clinical and laboratory, functional and immunohistochemical inspection 109 women with combined pathology of uterus and violation of genesial function. 1 (n=69) and 2 (n=19) groups were formed from patients with chronic endometritis and concomitant genital pathology. In 3 (n=21) groups there
were the included women after different endometrial manipulations. For the study of new aspects of pathogeny of violation of genesial function for women with combined pathology of uterus immunohistochemical researches of endometrium conducted the method of double antibodies with immunoperoxidase (streptovidin-biotinic) by a mark, used serial paraffin cuts.
Results. The retrospective study of the given medicare rotined that a desire to have children had served by reason of active treatment at the most inspected women. Anti-inflammatory (including antibacterial) therapy is before conducted at 93,3% patients, thus in the half of cases – repeatedly. Hormonal preparations were before appointed 66,2% to the patients. Endoscopic surgical interferences on the organs of the genesial system are executed for 46,7% patients. Used the more than half of women programs of auxiliary reproductive technologies which did not bring the desired effect. The results of laboratory-instrumental inspection confirmed a presence different structurally functional changes of endometrium, which could be an independent factor, impedimental to implantation and successful development of pregnancy. The increase of proangiogenic potential plays a considerable role in pathogeny of combined pathology of uterus and violations of genesial function.
Conclusions. Combined pathology of uterus is reason of violations of genesial function of women. The set nosotropic features testify to the necessity of more deep study of this problem for development of effective algorithm of diagnostic and лечебно-профилактических measures.
Features of infertility for women with different thyroid violations
Authors: Beraya Dzhanetti
Published: May 2022

The objective: study of frequency and structure of thyroid violations for women with infertility.
Materials and methods. For the performance of the put goal the screening estimation of pathology of thyroid was conducted for 298 women with infertility (basic group) and at 50 fertile of women which appealed to the clinic for the selection of method of contraception (control group). The inspection of patients with infertility was conducted in accordance with the generally accepted
diagnostic algorithm, including endoscopic methods, and treatment – depending on found out reasons of infertility
Results. Leading place in the structure of reasons of infertility for women with autoimmune thyroiditis occupied outward genital endometriosis (34,4%), for women with found out a thyroprivia is an endocrine factor of infertility (syndrome of polycystic ovaries) – 29,8%, for patients with the compensated thyroprivia is outward genital endometriosis (26,6%), for women with a euthyroid
goitre and for patients without pathology of thyroid is a pipe-peritoneal factor (33,3% and 39,8% accordingly). For patients with autoimmune thyropathy high-frequency of unmaturing of pregnancy is characteristic – at 2–2,4 time which exceeds analogical indexes in a control group.
Conclusion. For patients with infertility prevalence of thyroid pathology at 3,8 time higher by comparison to fertile women (48% and 12,5% accordingly). In the structure of pathology of thyroid the transmitter of antibodies prevails to thyroperoxidase in combination with the ultrasonic signs of autoimmune thyroiditis (24% and 8,7% accordingly); subclinical thyroprivia as a result of autoimmune thyroiditis (8,6% and 2,5% accordingly); euthyroid goitre (7,8% and 2,5% accordingly). The results of questionnaire, conducted for women with infertility, showed the low diagnostic value of clinical симптоматики of thyroprivia by comparison to laboratory diagnostics in verification of this diagnosis. A sensitiveness of symptoms was low and hesitated from 16,1% to 27,8%, while specificity of symptoms was considerable and varied from 85,1% to 94,5%.
New approach for determination of Phenylephrine HCl in Pure and Pharmaceutical Formulation using a various Microextraction Methods
Authors: K. Kareem Nagham , Z. Thani Mohammed , F.Al-Rawi Khalid
Published: May 2022

In this study, ion pair reactions used for evaluation of phenylephrine HCl the development of simple, accurate, low-cost, and fast extraction methods for the separation of phenylephrine HCl was described. The first method was used was the direct extraction that included the reaction PHE with Alizarin yellow reagent to produce yellow complex in the acidic medium (pH=4). The absorbance of this complex was 430nm. The concentration range (1-20µg.mL-1), the Beers law was obeyed with correlation coefficient (R2=0.997), limit of detection as (0.34µg.mL-1), limit of quantification as (1.12µg.mL-1) and molar absorptivity as (14459.9). The second method was dispersive liquid liquid microextraction (DLLME). This method was used to estimation PHE complex by utilizing UV-Vis spectrophotometer. The linearity of calibration curve above was the range between (0.5-13 µg.mL-1), the correlation coefficient (R2=0.996) and molar absorptivity was (12423.3), the detection limit (LOD) and quantification limit (LOQ) were (0.094µg.mL-1) and (0.31µg.mL-1), respectively. This process was successfully method to detect PHE in both pure and pharmaceutical formulations.
Biological Screening and Structure Activity relationship of Benzothiazole
Authors: Bhagdev Khyati , Sarkar Sibaji
Published: May 2022

Benzothiazole is a heterocyclic compound having nitrogen and sulphur. It's a bicyclic compound with a thiazole with benzene ring fused together. As per a review of the literature, benzothiazole is a primary moiety for the development of anticancer, antidiabetic, antioxidant, analgesic, and anti-inflammatory, antibacterial, antifungal, antiviral, anticonvulsant, antidepressant, antioxidant, and hepatoprotective agents. As a result, a list of biologically active benzothiazole derivatives has indeed been compiled in this study. The structure-activity relationship is analyzed based on the biological activities of benzothiazole derivatives and their substitution pattern. We also examined the mechanism of action of various benzothiazole derivatives, which can benefit researchers in the creation of new benzothiazole derivatives.
The Effect of Transformational Leadership Style in Crisis Management: Does Gender Matter?
Authors: Mohd@Ariffin Juliza Adira , Md Rami Ahmad Aizuddin , Abd Wahat Nor Wahiza , Nasharudin Nurfazreen Aina Muhamad
Published: May 2022

Leadership qualities in crisis management have become an important aspect to ensure the effectiveness of organizations in dealing with crises. According to Shift 8 for education at the primary to secondary school level and Shift 6 for higher education, the government emphasizes the need to transform the capabilities and capacity of leaders in an educational organization in Malaysia. One of the capabilities needed by the leaders in educational organizations to perform their job nowadays is crisis management competencies. Despite the importance of leadership skills in crisis management, there has been few research focused on this topic, particularly in educational institutions. Because of that, this research has been conducted to bridge this gap. The primary goal of this study is to investigate the implementation of a transformational leadership style by leaders during crisis management in their organisation as well as the impact of the implementation on subordinates and the influence of gender on the implementation of that style. Qualitative methods which are interviews through Focus Group Discussion (FGD) were conducted involving six (6) informants from different educational institutions to identify themes. Studies have shown that, among the four characteristics of transformational leadership, only three of them, which are idealized influence, inspirational motivation, and intellectual stimulation, were regularly practised by the leaders, with less implementation of the characteristics of individualized consideration during crisis management. The findings also show that transformational leadership positively impacts subordinates during times of crisis. In addition, the gender of the leader had a significant impact on the findings, with male leaders demonstrating more transformative leadership styles during crisis management than female leaders. Finally, this study's findings will contribute to a field of study in which many educational institutions can use them as a guide to evaluate and improve the quality of their future leaders.
Locating and Interrogating the Savarna Trace in Selected Marathi Dalit Short Stories
Authors: Ms. Somojyoti Banerjee
Published: May 2022

In the present time modern urban India denies the existence of caste prejudices and caste-based discriminations. Educated urban people talk of “caste” as concept which is centuries old and quite outdated. But how far it is true is a matter of question. Since even today when it comes to marriage, educated families look for boys or girls from the same caste, caste consciousness always remain at the back of the mind of an educated youth while forming the friend circle, and caste discrimination becomes more prominent when the so called educated modern urban families do not allow their domestic help to use the same plates. Down the ages it has been observed that the Savarnas or the so-called upper caste people have always occupied the central position in the society and continuously shaped and dictated the fate of the Dalits leaving them no choice to construct their lives according to their own will and wish.   Literature, however, has always been the mimetic platform which has inspired the common people to rethink, reevaluate and bring about reformative and revolutionary changes. The present paper attempts to hear those unheard voices of the Dalits who have long been oppressed by the upper caste people in this casteist Indian society. The present paper analyses two short stories written by two prolific Dalit writers namely Baburao Bagul and Sharankumar Limbale. Through a close reading of Bagul’s “When I Hid My Caste” and Limbale’s “The Dalit Brahmin”, the present paper aims to identify and comprehend how instrumental and phenomenal is the trace of the upper caste in the lives of the Dalits and how this hegemonic savarna social system has caused the unbuilding of the identity which the Dalits have so ambitiously built equal to that of the Savarnas.
Developing Protection-Use-Strategies Based On Sustainability in Protected Areas: Suuçtu Nature Park Case
Authors: PİRSELİMOĞLU BATMAN Zeynep , ÖZUÇAR Pelin
Published: May 2022

This study aims to evaluate the current conservation and use status in a nature park and to develop planning strategies that will provide sustainable use of protected areas for the future. Suuçtu Nature Park in Bursa Province Mustafakemalpaşa district was chosen as the study area. The method of the study consisted of three stages. In the first stage, the current situation was revealed by conducting fieldwork, observations, and interviews. In the second stage, SWOT analysis was carried out to determine the recreational opportunities offered by the area and to evaluate the potential of the study area. It has been determined by SWOT analysis that Suuçtu Nature Park is a strong character due to its unspoiled natural and cultural values, ideal climate characteristics, geological structure and high visual landscape value. In the third stage, conservation and tourism strategies for the future were developed with the TOWS matrix. As a result of the study, by considering the protection and usage conditions of the area, land use strategies have been developed in line with ecological-based tourism and recreation uses in the protected areas.
Endodontic treatment of large periapical lesions: An alternative to surgery
Authors: Mendoza-Mendoza Asunción , Caleza-Jiménez Carolina , Iglesias-Linares Alejandro , Solano-Mendoza Beatriz , RM Yañez-Vico
Published: May 2022

Introduction: Non-surgical treatment with calcium hydroxide offers a high success rate in the healing of large periapical lesions. Case Series: We present the healing of large periapical lesions with conservative, non-surgical treatment in three young patients presenting large periapical lesions and diagnosed with chronic periapical periodontitis. Non-surgical endodontic treatment was carried out involving canal preparation, irrigation with 2.5% sodium hypochlorite, filling of the canal with 75% calcium hydroxide and 25% Kri-1 iodoform paste mixed with sterile saline solution, and sealing of the cavity with composite. The filling was replaced several times, after which endodontic treatment was finally carried out. Complete apical healing was observed in all cases. Conclusion: Non-surgical treatment as a first option allows us to avoid the trauma of surgery in young individuals.
Şeffaflık İlkesinin Rus Yönetim Kültürü Bağlamında Değerlendirilmesi: Gorbaçov Dönemi
Authors: DURMUŞ Merve , YİĞİT Yegane
Published: May 2022

Tarihsel bir miras olarak yüzyıllar boyunca aktarılan yönetim kültürü, dönemin getirdiği şartlara öz değerlerinden taviz vermeden ayak uydurma eğiliminde olmaktadır. Farklı kültürlere ait değerler mevcut yönetim kültürüne adapte edilmeden doğrudan aktarılmaya çalışıldığında idari sistemde sıkıntılara yol açabilmektedir. Bu kapsamda çalışmanın amacı Rus yönetim kültürünün batı kökenli şeffaflık uygulamalarına nasıl bir etkide bulunduğunu ortaya koymaktır. Bu amaçla çalışmada büyük bir sistemin çöküşüne şahitlik edilen Gorbaçov döneminde uygulanan batı kökenli şeffaflığın yönetsel alanda oluşturduğu infiale dikkat çekmeye çalışılmıştır. Sistemsel durgunluğun ortadan kaldırılmasına yönelik başlatılan yeniden yapılanma sürecinde uygulanan şeffaflık ilkesi aslında beklenenin aksine bir tablo ortaya çıkarmıştır. Gorbaçov’un gizlilik, dışa kapalılık, katı hiyerarşik yapı ve merkeziyetçilik ilkelerinden beslenen Asya despotik geleneğinin baskın olduğu Rus yönetim kültürü ile Batı menşeili bir değer olan şeffaflık uygulamalarını harmanlama çabasının başarısızlıkla ve hatta devletin çöküşüyle sonuçlandığı görülmüştür. Bu bağlamda iktidarın gücü elinde tutma eğilimine dayalı köklü Rus geleneğindeki hâkim devlet anlayışı sistemin çöküşü pahasına da olsa yeni paradigmalara kapalılığını istikrarlı bir şekilde ortaya koymuştur.
Investigation of a foodborne outbreak at a mass gathering in Petaling District, Selangor, Malaysia
Authors: Rajakrishnan Sudeash , Hafiz Ismail Muhd Zulfadli , Jamalulail Syed Hafeez , Alias Norazmalia , Ismail Hassan , Md Taib Salina , Cheng Lee Soo , Zakiman Zazarida , Ong Richai , Silverdurai Rubaan Raj , Yusof Mohamad Paid
Published: May 2022

Objective: On 6 October 2019, Petaling District Health Office received notification of a possible foodborne outbreak involving a mass gathering event. This report presents the processes of diagnosis verification, case identification, determination of associated risk factors and commencement of control measures in managing the outbreak. Methods: Cases were defined as those who attended the mass gathering event on 6 October 2019, consumed the pre-packaged food and subsequently developed vomiting, abdominal pain, diarrhoea or other symptoms (e.g. fever, nausea and dizziness). Epidemiological, environmental and laboratory investigations were performed. Data were analysed using SPSS software (version 24.0). Results: A total of 169 cases were identified. The attack rate was 7.2%, and cases ranged in age from 7 to 50 years, with a median of 20 years. A total of 156 (92.3%) cases had vomiting, 137 (81.1%) had abdominal pain and 83 (49.1%) had diarrhoea. Consuming nasi lemak at the mass gathering was found to be significantly associated with developing illness (odds ratio: 9.90, 95% confidence interval: 6.46–15.16). The samples from suspected food, food handlers and the environment were positive for Bacillus cereus, Staphylococcus aureus or coliforms. Discussion: The outbreak at this mass gathering was probably caused by food contaminated with B. cereus and S. aureus. To prevent future outbreaks, we recommend mass gathering events use certified catering services that have adequate food safety training.
Epidemiology of coinfection with tuberculosis and HIV in Japan, 2012–2020
Authors: Kawatsu Lisa , Uchimura Kazuhiro , Kaneko Noriyo , Imahashi Mayumi
Published: May 2022

This report examines the characteristics and treatment outcomes of patients with tuberculosis (TB) who are coinfected with HIV in Japan. Active TB cases newly notified to the Japan Tuberculosis Surveillance system during 2012–2020 were analysed retrospectively, during which 379 HIV-positive TB cases were reported. The proportion of HIV-positive cases among those with known HIV status increased, from 1.9% (62/3328) in 2012 to 3.5% (31/877) in 2020. The proportion of those with unknown HIV testing status was consistently high, at approximately 60%, and the proportion of those who did not undergo HIV testing increased significantly, from 21.6% (4601/21 283) in 2012 to 33.7% (4292/12 739) in 2020. The proportion of foreign-born cases more than tripled, from 14.5% (9/62) in 2012 to 45.2% (14/31) in 2020. The TB treatment success rate was higher among HIV-negative than HIV-positive cases (72.7% [3796/5222] versus 60.3% [88/146]), and among Japan-born than foreign-born HIV-positive patients (65.6% [61/93] versus 50.9% [27/53]), owing largely to the high rate of foreign-born cases transferring to care outside Japan. The increasing proportion of HIV positivity among TB cases tested for HIV in this study requires ongoing monitoring, especially among foreign-born persons. However, because the number of reported cases was small, and there was low completeness of reporting of HIV testing data in the TB surveillance system, these results should be interpreted with caution. Encouraging more complete data collection by training public health nurses who complete TB case interviews and ensuring ongoing monitoring of patients with TB/HIV coinfection are recommended.
novel dynamic route aware clustering (DRAC) protocol for enhancing energy efficiency by clustering concept in WSN
Authors: Sajitha M. , Veni S.
Published: May 2022

"Wireless Sensor Networks (WSNs)" have started to recognize clustering as among the best effective ways of saving energy. The Cluster-Heads (CHs) probably have spent higher energy than typical nodes in a WSN based on clustering, resulting in higher consumption of energy and a shorter network lifespan. To lower the consumption of energy of CHs, many energy-efficient routing techniques had already been developed and demonstrated. It is possible to reduce the consumption of energy of CHs by increasing the number of CHs nearby. Earlier research has not taken into account these conditions. Poorly balanced CH consumption of energy is also a major design concern, resulting in increased misspent energy and initial network downfall. These situations need re-creation of the shortest path route if the previously found routed path is faulty or interrupted. Extra node consumption of energy may exhaust the sensor's energy supply as a result of this reconfiguration. Researchers in the last several years also aimed to enhance the overall balance of energy through the use of huge and costly energy harvesting equipment but nothing had solved this issue.
challenges and opportunities of tourism management practices in Afar National Regional State, Ethiopia
Authors: Mekonnen Thomas Haile , Ibrahim Blesa , Andavara Venketesh
Published: May 2022

Afar region has potential for attracting tourists because it has located in the North - Eastern part of Ethiopia and it is the lowest area. the Afar  Regional State, major destination challenges related to community participation, community organizations, benefit sharing mechanism, knowledge of the society about tourism, funding for tourism development, facilities and services in a destination, organizational structure, infrastructural development and stakeholder coordination have not been properly examined. Therefore, the objective of this study was to identify the major challenges and opportunities of tourism development in the Afar national regional state in the case of Ertale and Adar woreda. The design of the study is descriptive and has employed both quantitative and qualitative research approaches. The researcher used instruments such as interview, questionnaire, focus group discussion and existing secondary sources for data gathering. The finding of the study shows many challenges and opportunities of tourism development in Afar region. The main challenges include bureaucratic problem, in sufficiency of basic infrastructures, low promotion in the sector, macroeconomic instability and problem of implementation capacity.
Managing strategies of transformational leadership to create service standard of boutique hotel in Thailand
Authors: Charoenboon Pawintana , Chankaew Keattisak
Published: May 2022

The boutique hotels were more of an independent kind of lodging are unlike other hotels in terms of architecture and decoration, as the majority of them are tall buildings. The boutique hotels will exude a distinct sense of place. The tourists are interested in learning about the local culture. Boutique hotels are popular with guests who want to learn about diverse cultures and traditions. Investigate the techniques of change agents in order to build a boutique hotel service standard. Study change leaders' common or unique techniques for building a standard of service boutique hotel in Thailand, and define change leaders' strategies for establishing a standard of service boutique hotel. The major informants were 25 hotel managers and directors from boutique hotels. Grounded theory research of qualitative research using in-depth interview within observation method. The results of the study revealed that, in the idealized influence aspect, hotels leaders used experiences. Expertise in management and problem solving in terms of inspiration motivation, the focus is on communication mainly through discussion, intellectual stimulation, and leadership listening to opinions and support problem solving ideas of employees Individualized consideration take care of employees individually and affect to employees feeling valued and important technology.
Study on handwriting features of ambidextrous persons by using image processing
Authors: Moinuddin Siddiqui Mohammed Khaja , Kumar Suneet , Ahmed Sayeed , Jain Arvind Kumar
Published: May 2022

Handwriting Features of Ambidextrous Persons have been classified as a multi-class classification issue in the deep learning framework, where image recognition task is effectively to test a classifier who can efficiently discriminate each line of paragraph of handwriting. This is very common for a single classifier to be performed on different data sets with a standard deep learning algorithm. It may also be that the same classifying system performs differently with highly differing image instances due to the various manuscript styles of various people on the same numbers. In order to address this problem, it was crucial to develop ensemble learning approaches to enhance overall effectiveness and make the performance highly stable in various data sets. In this text, we are proposing a system involving the CNN-based removal of the data set from an image and algebraic fusion of various words in images to classifies for trained in different sets of edges, which are prepared by means of feature selection applied to the original CNN feature set. Experimental results show that a fusion of classification images can achieve a descriptive word.