bluuebunny/crossref_metadata_2025 huggingface dataset:
Fermentation of Green Tea with 2% Aquilariae lignum Increases the Anti-Diabetic Activity of Green Tea Aqueous Extracts in the High Fat-Fed Mouse
Authors: Lee Ji , Kang Su , Choi Seong , Song Chang , Lee Young , Ku Sae
Published: November 2015

Anti-diabetic effects on the metabolomic differences between green tea (GT) and Aquilariae lignum-fermented green tea (fGT) were investigated in the high fat-fed mouse. To prove the differences, hypoglycemic (blood glucose, insulin and glycated hemoglobin levels, pancreas weights and histopathological-immunohistochemistrical analysis of pancreas–insulin/glucagon cells), hepato- and nephron-protective (the changes in liver and kidney weight, histopathology of liver and kidney, serum aminotransferases (AST and ALT) levels, blood urea nitrogen, and serum creatinine levels), and hypolipidemic (the changes of serum total cholesterol, triglyceride, low- and high-density lipoprotein levels with fecal total cholesterol (TC) and triglyceride (TG) contents) effects were evaluated. In addition, liver lipid peroxidation, the glutathione contents, and catalase and superoxide dismutase activities were measured according to the hepatic glucose-regulating enzyme activities of glucokinase (GK), glucose-6-phosphatase (G6pase) and phosphoenolpyruvate carboxykinase (PEPCK) for action mechanisms. As a result, fGT showed a stronger hypoglycemic, hepato- and nephron-protective, hypolipidemic, and anti-oxidant effect than GT in high fat-fed mice. In addition, fGT-treated mice exerted more favorable inhibitory activities against GK, G6pase, PERCK activities as compared to GT-treated mice. Taken together, fGT fermented with Aquilariae lignum, 1:49 (2%; g/g) has a stronger effect compared with GT. Therefore, fGT has the potential to increase bioactivity against type 2 diabetics.
Static Stability Analysis of a Planar Object Grasped by Multifingers with Three Joints
Authors: Yamada Takayoshi , Johansson Rolf , Robertsson Anders , Yamamoto Hidehiko
Published: November 2015

This paper discusses static stability of a planar object grasped by multifingers with three joints. Each individual joint (prismatic joint or revolute joint) is modeled as a linear spring stiffness. The object mass and the link masses are also included. We consider not only pure rolling contact but also frictionless sliding contact. The grasp stability is investigated using the potential energy method. This paper makes the following contributions: (i) Grasp wrench vectors and grasp stiffness matrices are analytically derived not only for the rolling contact but also for the sliding contact; (ii) It is shown in detail that the vectors and the matrices are given by functions of grasp parameters such as the contact conditions (rolling contact and sliding contact), the contact position, the contact force, the local curvature, the link shape, the object mass, the link masses, and so on; (iii) By using positive definiteness of the difference matrix of the grasp stiffness matrices, it is analytically proved that the rolling contact grasp is more stable than the sliding contact grasp. The displacement direction affected by the contact condition deviation is derived; (iv) By using positive definiteness of the differential matrix with respect to the local curvatures, it is analytically proved that the grasp stability increases when the local curvatures decrease. The displacement direction affected by the local curvature deviation is also derived; (v) Effects of the object mass and the joint positions are discussed using numerical examples. The numerical results are reinforced by analytical explanations. The effect of the link masses is also investigated.
Superpixel-Based Roughness Measure for Multispectral Satellite Image Segmentation
Authors: Ortiz Toro César , Gonzalo Martín Consuelo , García Pedrero Ángel , Menasalvas Ruiz Ernestina
Published: November 2015

The new generation of artificial satellites is providing a huge amount of Earth observation images whose exploitation can report invaluable benefits, both economical and environmental. However, only a small fraction of this data volume has been analyzed, mainly due to the large human resources needed for that task. In this sense, the development of unsupervised methodologies for the analysis of these images is a priority. In this work, a new unsupervised segmentation algorithm for satellite images is proposed. This algorithm is based on the rough-set theory, and it is inspired by a previous segmentation algorithm defined in the RGB color domain. The main contributions of the new algorithm are: (i) extending the original algorithm to four spectral bands; (ii) the concept of the superpixel is used in order to define the neighborhood similarity of a pixel adapted to the local characteristics of each image; (iii) and two new region merged strategies are proposed and evaluated in order to establish the final number of regions in the segmented image. The experimental results show that the proposed approach improves the results provided by the original method when both are applied to satellite images with different spectral and spatial resolutions.
A Spiking Neural Network in sEMG Feature Extraction
Authors: Lobov Sergey , Mironov Vasiliy , Kastalskiy Innokentiy , Kazantsev Victor
Published: November 2015

We have developed a novel algorithm for sEMG feature extraction and classification. It is based on a hybrid network composed of spiking and artificial neurons. The spiking neuron layer with mutual inhibition was assigned as feature extractor. We demonstrate that the classification accuracy of the proposed model could reach high values comparable with existing sEMG interface systems. Moreover, the algorithm sensibility for different sEMG collecting systems characteristics was estimated. Results showed rather equal accuracy, despite a significant sampling rate difference. The proposed algorithm was successfully tested for mobile robot control.
Cytotoxic Indole Alkaloids against Human Leukemia Cell Lines from the Toxic Plant Peganum harmala
Authors: Wang Chunhua , Zhang Zhenxue , Wang Yihai , He Xiangjiu
Published: November 2015

Bioactivity-guided fractionation was used to determine the cytotoxic alkaloids from the toxic plant Peganum harmala. Two novel indole alkaloids, together with ten known ones, were isolated and identified. The novel alkaloids were elucidated to be 2-(indol-3-yl)ethyl-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside (2) and 3-hydroxy-3-(N-acetyl-2-aminoethyl)-6-methoxyindol-2-one (3). The cytotoxicity against human leukemia cells was assayed for the alkaloids and some of them showed potent activity. Harmalacidine (compound 8, HMC) exhibited the highest cytotoxicity against U-937 cells with IC50 value of 3.1 ± 0.2 μmol/L. The cytotoxic mechanism of HMC was targeting the mitochondrial and protein tyrosine kinase signaling pathways (PTKs-Ras/Raf/ERK). The results strongly demonstrated that the alkaloids from Peganum harmala could be a promising candidate for the therapy of leukemia.
De l’évaluation participative des besoins à la conception du plan d’action. L’exemple du réseau d’écoute, d’appui et d’accompagnement des parents en Ardèche
Authors: Girault Olivier , Torres Grégory
Published: November 2015

fre: Soutien à la parentalité ,Diagnostic partagé , Plan d’action local , Reaap
I Remember it Well: Epiphanies, Nostalgia, and Urban Exploration As Mediators of Tourist Memory
Authors: Robinson Peter
Published: November 2015

This article takes the author's own nostalgic feelings for a now defunct theme park and translates these into an analysis of other people's tourism-related nostalgic experiences. In doing so, the article furthers discussion around nostalgia and memory within tourism and approaches new
ground in the use of images, online forums, and urban exploration as mediators of individual and shared nostalgias. It has also been argued that while nostalgia is a key motivational factor in tourist decision making, it has not been fully explored. Furthermore, this article uniquely focuses
on younger people where previous research has considered older age groups. As a consequence, the semiautoethnographic discussion, supported with quantitative and phenomenological content analysis of online forums, explores the creation of tourist epiphanies and identifies key themes around
family, repeat visitation, and the preplanned creation of new nostalgias within hyperreal environments.
Stability of Tigecycline in Different Types of Peritoneal Dialysis Solutions
Authors: Robiyanto Robiyanto , Zaidi Syed Tabish R. , Shastri Madhur D. , Castelino Ronald L. , Wanandy S. Troy , Jose Matthew D. , Patel Rahul P.
Published: November 2015

Introduction

Intraperitoneal tigecycline is a potential option for the treatment of peritoneal dialysis (PD)-associated peritonitis caused by microorganisms resistant to commonly used antibiotics. However, the stability of tigecycline must be assessed in the PD solution before evaluating its safety and therapeutic efficacy in PD-associated peritonitis. The objective of this study was to investigate the stability of tigecycline in 3 types of PD solutions at different temperatures for various time points.

Methods

A total of 27 PD bags (9 PD bags for each type of PD solution; 1.5% glucose, 7.5% icodextrin, and 1.5% glucose pH neutral) containing 2 μg/mL of tigecycline were prepared and stored at either 4, 25, or 37°C. An aliquot was withdrawn immediately before (0 hour) and after pre-defined time points. Each sample was analyzed in duplicate for the concentration of tigecycline using a stability-indicating high-performance liquid chromatography (HPLC) technique. Samples were also assessed for pH, color changes, and evidence of precipitation immediately after preparation and on each day of analysis.

Results

Tigecycline in all 3 types of PD solutions retained more than 90% of its initial concentration for at least 216, 72, and 8 hours at 4, 25, and 37°C, respectively. There was no evidence of precipitation at any time under the tested storage conditions. The pH and color of tigecycline admixed PD solutions stored at 4, 25, and 37°C remained essentially unchanged for 336, 96, and 48 hours respectively.

Conclusion

The results obtained from the study provide a platform for future clinical studies aiming to determine the safety and therapeutic efficacy of intraperitoneally administered tigecycline for the treatment of PD-associated peritonitis.
A new approach to ferrocene derived alkenes via copper-catalyzed olefination
Authors: Muzalevskiy Vasily M , Shastin Aleksei V , Demidovich Alexandra D , Shikhaliev Namiq G , Magerramov Abel M , Khrustalev Victor N , Rakhimov Rustem D , Vatsadze Sergey Z , Nenajdenko Valentine G
Published: November 2015

A new approach to ferrocenyl haloalkenes and bis-alkenes was elaborated. The key procedure involves copper catalyzed olefination of N-unsubstituted hydrazones, obtained from ferrocene-containing carbonyl compounds and hydrazine, with polyhaloalkanes. The procedure is simple, cheap and could be applied for the utilization of environmentally harmful polyhalocarbons. The cyclic voltammetry study of the representative examples of the synthesized ferrocenyl alkenes shows the strong dependence of the cathodic behavior on the amount of vinyl groups: while for the monoalkene containing molecules no reduction is seen, the divinyl products are reduced in several steps.
Cholesterol lowering effects of mono-lactose-appended β-cyclodextrin in Niemann–Pick type C disease-like HepG2 cells
Authors: Motoyama Keiichi , Hirai Yumi , Nishiyama Rena , Maeda Yuki , Higashi Taishi , Ishitsuka Yoichi , Kondo Yuki , Irie Tetsumi , Era Takumi , Arima Hidetoshi
Published: November 2015

The Niemann–Pick type C disease (NPC) is one of inherited lysosomal storage disorders, emerges the accumulation of unesterified cholesterol in endolysosomes. Currently, 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD) has been applied for the treatment of NPC. HP-β-CyD improved hepatosplenomegaly in NPC patients, however, a high dose of HP-β-CyD was necessary. Therefore, the decrease in dose by actively targeted-β-CyD to hepatocytes is expected. In the present study, to deliver β-CyD selectively to hepatocytes, we newly fabricated mono-lactose-appended β-CyD (Lac-β-CyD) and evaluated its cholesterol lowering effects in NPC-like HepG2 cells, cholesterol accumulated HepG2 cells induced by treatment with U18666A. Lac-β-CyD (degree of substitution of lactose (DSL) 1) significantly decreased the intracellular cholesterol content in a concentration-dependent manner. TRITC-Lac-β-CyD was associated with NPC-like HepG2 cells higher than TRITC-β-CyD. In addition, TRITC-Lac-β-CyD was partially localized with endolysosomes after endocytosis. Thus, Lac-β-CyD entered NPC-like HepG2 cells via asialoglycoprotein receptor (ASGPR)-mediated endocytosis and decreased the accumulation of intracellular cholesterol in NPC-like HepG2 cells. These results suggest that Lac-β-CyD may have the potential as a drug for the treatment of hepatosplenomegaly in NPC disease.
IDENTIFICATION AND HIERARCHICAL STRUCTURE OF CRITICAL SUCCESS FACTORS FOR INNOVATION IN CONSTRUCTION PROJECTS: CHINESE PERSPECTIVE
Authors: LIU Hui , SKIBNIEWSKI Miroslaw J. , WANG Mengjun
Published: November 2015

This paper identifies 20 critical success factors (CSFs) of innovation in China’s construction projects through literature review, a case study and expert interviews. Integrated Structural Modeling (ISM) and MICMAC (Impact Matrix Cross-reference Multiplication Applied to a Classification) analysis were used to hierarchically structure CSFs as well as to analyze their inter-relationships. The dependence and driver power of each factor were also analyzed. By doing this, this paper presents structural clarity and establishes a hierarchical order for prioritization for the decision-making. The findings show that most of the CSFs (19 out of 20) have strong inter-relationships. According to the law of vital few and trivial many, 80% of effects come from 20% of the causes for many events. This paper suggests that intensive effort should focus on the root source of CSFs: owner’s involvement and leadership, top management com­mitment, and strategic importance of the innovation project. Besides, external support, which is beyond the innovation project network, plays an important role in the success of innovation in China’s construction projects.
A STUDY FOR SUSTAINABLE DEVELOPMENT IN OPTOELECTRONICS INDUSTRY USING MULTIPLE CRITERIA DECISION MAKING METHODS
Authors: LIU Chun-Chu , CHENG An-Chin , CHEN Shih-Hui
Published: November 2015

This study assessed the operational efficiency of the optoelectronics industry in the Southern Taiwan Science Park (STSP) between 2007 and 2011 by using multiple criteria decision making methods (data envelopment analysis, Malmquist productivity index and Bootstrap). The data analysis showed that during the study period, meaning that the operational efficiency gap among manufacturers in STSP is widening. Among these manufacturers, eight manufacturers exhibited constant returns to scale, which was more than a half of the overall decision making unit (DMU), indicating that the operational scale of these manufacturers was nearing the optimal scale. Based on Malmquist productivity index (MPI) analysis, the factors that affect the operational efficiencies of optoelectronics manufacturers’ were as follow: operational cost, the number of employees, and the amount of fixed assets. The development should be focused on increasing technological efficiency and technological change in the future. Finally, based on Bootstrap, the results showed that the focus should be on the production technology while improving productive efficiency to ensure sustainable development of the entire domestic optoelectronics industry in the future.
HOW DOES PATENT LITIGATION INFLUENCE DYNAMIC RISK FOR MARKET COMPETITORS?
Authors: WANG Yi-Hsien , LIN Wan-Rung , LIN Shu-Shian , HUNG Jui-Cheng
Published: November 2015

Many recent studies have discussed the appropriateness of various patent measurement indicators, as well as the differences in the positioning of patented technologies, while there is little discussion on the risk transmission of enterprises when faced with infringement litigation. This study used the bivariate EGARCH (Exponential Generalized Autoregressive Conditional Heteroskedasticity) model with DCC (Dynamic Conditional Correlations) to investigate the dynamic risk transmission of patent litigation between market competitors in the smartphone industry. Empirical results revealed that when facing lawsuits from market challengers, the market leader faces fewer risks when handling patent infringement litigations. In addition, the risk reactions of competitors during patent wars may widely differ. Investors should consider the patent infringement litigations when measuring the dynamic risks of share prices, and determining the optimal configuration of asset portfolios in response.
A LITERATURE REVIEW OF THE FACTORS LIMITING THE APPLICATION OF BIM IN THE CONSTRUCTION INDUSTRY
Authors: SUN Chengshuang , JIANG Shaohua , SKIBNIEWSKI Miroslaw J. , MAN Qingpeng , SHEN Liyin
Published: November 2015

Building Information Modeling (BIM) has had a profound effect on the construction industry. It has greatly improved coordination among stakeholders, enhanced productivity, and increased profits. However, many factors still limit the application of BIM in the construction industry. This study conducts a literature review to identify these negative factors. Firstly, twenty-two sub-factors are identified and classified into five categories: Technology, Cost, Management, Personnel, and Legal. Secondly, some suggestions for eliminating these limiting factors are given. Finally, the study also identifies further research directions for improving BIM theory and applying BIM technology widely and successfully. The results of this study will provide support for practitioners who are using or plan to use BIM.
Some Remarks about the Professional Military Education of Officers
Authors: Zůna Jaromír , Pernica Bohuslav
Published: November 2015

Each officer is obligated to meet his or her qualification requirements, identified in the job description. In order to obtain a required military qualification, officers are usually send to a training course, which is either provided or organized under the auspice of the Ministry of Defence. The discussion within the Armed Forces of the Czech Republic about the system of military courses has been ongoing for the last two decades. Although the system of officers´ development is periodically reviewed, a certain economic paradox still remains. While the number of officers without adequate qualification is not diminishing, at the same time there is a segment of officers who exceed their qualification requirements, but they do not make any progress in their military careers. Despite the situation, these officers are required to take additional training and educational activities.
Space Policy through the Prism of the Concept of Strategic Culture
Authors: Fučík Jakub , Suchý Petr
Published: November 2015

The article deals with the issue of creation and realization of space policy. Space programs of individual states are closely connected to decision-making processes of the (general) state (public) policy. Therefore we can raise a question which factors influence these processes and the formulation of space policy and also if they are so unique that could be related only to one particular state. The aim of this article is to focus on one of the factors influencing space policy-strategic culture. Its influence is analysed through case studies of seven nations. Each case study is divided into two parts. First, we identify relevant characteristics of the state's strategic culture. Then, we analyse whether and how the identified characteristics of the respective strategic culture influence the space policy of a state in question. This article seeks to contribute to the growing debate about space as "the next" strategic area and highlights rather overlooked reasons of space exploration.
Why to Afghanistan? Skills, Money or Ideals?
Authors: Laštovková Jitka , Bernardová Kateřina
Published: November 2015

The motivation and professional values of soldiers involved in Other People's Wars is one of the most important knowledge necessary for effective command and control. Those were main reasons for an extensive questionnaire survey among soldiers, deployed in PRT ISAF in 2010-2011. One of the key topics was motivation to leave for Afghanistan, professional expectations and evaluations of external and internal environment of the mission. The purpose of this paper is to present the basic outlines of values of today's Czech soldiers, their professional motives and expectations. The results are interpreted in the context of Moskos' theory of the contradiction between institutional and occupational orientations of present armed forces and adapted to the actual social and political state of affairs.
Communicating in 140 characters. How journalists in Spain use Twitter
Authors: Arrabal-Sánchez Gabriel , de-Aguilera-Moyano Miguel
Published: November 2015

The emergence of Twitter appears to be changing information practices. Hence, a great deal of recent research is based on its popularity among communicators, reaching the conclusion that it serves to increase interactivity with readers. But to what degree is it true that it contributes to a type of journalism which is more open to the public? This research aims especially to clarify two main questions: what specific uses do journalists make of Twitter and to what extent does twoway interaction with the public take place through this medium? It is based on the quantitative analysis of a sample comprising almost 5 million tweets posted by 1,504 Spanish media communicators, perhaps the largest sample studied so far. The analysis shows the existence of a twospeed Twitter (with a minority of influential communicators and a majority who have little impact), which has negligible interaction with followers. With few exceptions, the communicators establish endogamous relationships on Twitter. They respond to mention and retweet colleagues, failing to take advantage of the multidirectional potential offered by the platform. This research expands the empirical basis which can be used to consider and discuss the scope and limits of user participation in information events. Many authors have theorized on this subject, perhaps too enthusiastically and arguably from a somewhat utopian perspective.

La irrupción de Twitter parece estar cambiando las prácticas informativas. De ahí que bastantes investigaciones recientes partan de su popularidad entre los comunicadores para concluir que sirve para aumentar la interactividad con los lectores. Pero ¿hasta qué punto es cierta su contribución a un periodismo más abierto a la ciudadanía? Este trabajo busca sobre todo contribuir a clarificar dos cuestiones principales: qué usos concretos dan a Twitter los periodistas y hasta qué punto se mantiene esa interacción ?de ida y vuelta? con la ciudadanía gracias a este medio. Se basa en el análisis cuantitativo de una muestra de casi cinco millones de tuits correspondientes a 1.504 comunicadores de medios españoles; probablemente, la mayor muestra estudiada hasta ahora. El análisis constata la existencia de un Twitter a dos velocidades (con una minoría de comunicadores muy influyente y una mayoría con escaso impacto), pero una interacción con los seguidores prácticamente nula. Salvo excepciones, los comunicadores establecen en Twitter relaciones muy endogámicas, respondiendo, retuiteando y mencionando a colegas, desaprovechando así las potencialidades multidireccionales que ofrece esta plataforma. Esta investigación amplía la base empírica con la que pensar y discutir el alcance y los límites de la participación de los usuarios en los fenómenos informativos, que tantos autores han teorizado, quizá, con demasiado entusiasmo y, sin duda, con una perspectiva en cierta medida utópica.
European newspapers’ digital transition: New products and new audiences
Authors: Peña-Fernández Simón , Lazkano-Arrillaga Iñaki , García-González Daniel
Published: November 2015

The adaptation of traditional newspapers to new digital media and its interface, far from being a mere technical transformation, has contributed to a gradual change in the media themselves and their audiences. With a sample including the top general information pay newspaper in each of the 28 countries of the European Union, this research has carried out an analysis using 17 indicators divided in 4 categories. The aim is to identify the transformations that the implementation of digital media have brought to the top European newspapers. In general terms, the results show that most dailies have managed to keep their leadership also in online environment. Moreover, an emerging group of global media is growing up, based in preexisting national media. Digital and mobile media have contributed to the appearance of new consumption habits as well, where users read more superficially and sporadically. The audience uses several formats at a time, and digital devices already bring the biggest amount of users to many media. The Internet-created new information windows –search engines, social networks, etc. –are also contributing to the change in professional work routines.

La adaptación de los medios de comunicación tradicionales a los nuevos soportes digitales y su interfaz, lejos de constituir un mero ajuste técnico, ha contribuido a una paulatina transformación de los propios medios y sus audiencias. En una muestra integrada por los diarios de información general y de pago líderes en los 28 países de la UE, y mediante el análisis de 17 indicadores distribuidos en cuatro categorías, este artículo busca identificar las transformaciones que la implantación de los soportes digitales han provocado en las principales cabeceras de la prensa europea. En términos generales, los resultados de la investigación señalan que la mayoría de los diarios no sólo han logrado mantener su liderazgo en la Red, sino que en algunos casos también se está alumbrando un incipiente conjunto de medios globales a partir de medios nacionales preexistentes. Los soportes digitales y móviles también han favorecido la aparición de nuevos hábitos de consumo, caracterizados por una lectura más esporádica y superficial por parte de los usuarios, y han configurado una audiencia que ya en muchos casos es multisoporte, y donde los dispositivos digitales aportan ya la mayoría de lectores a muchos medios. Asimismo, las nuevas ventanas de acceso a la información –buscadores, redes sociales, etc.– generadas por Internet, también están contribuyendo decisivamente al cambio de las rutinas y las formas de trabajo de los propios medios.
Du pouvoir citoyen au pouvoir populaire : l’institutionnalisation de l’action politique des femmes au Venezuela
Authors: Brandler-Weinreb Jessica
Published: November 2015

Avec l’arrivée au pouvoir de Hugo Chávez le Venezuela a changé de régime politique et adopté dans la Constitution de 1999 le projet de « démocratie participative et protagonique » (protagónica). La centralité des Conseils communaux dans cette politique de la participation a permis de valoriser les « territoires quotidiens » comme niveau d’action et comme espaces investis par des acteurs précis, majoritairement des femmes. Il convient donc de se demander en quoi le « pouvoir populaire » du socialisme du XXIe siècle a quitté le registre de la citoyenneté de l’État libéral, créée par et pour les hommes, pour valoriser les compétences des femmes en politique et s’inspirer de leurs pratiques ? L’effondrement de la division État-société qui a accompagné la mise en place des Conseils communaux a permis de reconnaître le caractère politique de l’action locale des femmes. Cependant, il pose également la question de l’affiliation partisane dans l’engagement politique et, paradoxalement, de l’autodétermination du pouvoir qu’il permet.
Psychodynamique de la reconnaissance au travail et identité
Authors: Potiron Marie
Published: November 2015

La psychodynamique du travail développe une théorie de la reconnaissance spécifique, qui élargit les propositions freudiennes à propos de la sublimation et implique le développement d’une théorie de l’identité et se propose d’élargir les propositions freudiennes à propos de la sublimation. Elle implique une théorie de l’identité particulière. Cet article constitue une présentation de ce qu’est la psychodynamique de la reconnaissance, de son histoire théorique et des ses articulations avec la sublimation freudienne et avec une théorie de l’identité.
Fiction, délire, virtuel
Authors: Thibierge Stéphane
Published: November 2015

L’on interroge ici l’incidence et les conséquences cliniques et subjectives du virtuel, tel qu’il détermine aujourd’hui l’environnement technique et quotidien de l’existence ordinaire. Sont évoquées et reprises de ce point de vue les distinctions entre virtuel et réalité, virtuel et fiction, fiction et délire, et la notion de jouissance, telle que la sollicite la clinique contemporaine. L’on montre également en quoi la lecture et son apprentissage, et l’interprétation qu’elles rendent possible du trait symbolique, peuvent donner ou restituer une responsabilité subjective parfois compromise ou désorientée par une confusion des registres précédemment cités.
Le personnage, figure de l’autre en soi
Authors: Guénoun Tamara
Published: November 2015

Cet article analyse la scène psychique au travers du paradigme de la scène théâtrale sous l’angle original du processus créateur de l’acteur. En quoi est-ce que le jeu d’incarnation du personnage mobilise le comédien dans un nouveau rapport à soi et à l’autre ? L’analyse du processus psychique d’incarnation du personnage amène à considérer des problématiques subjectives complexes. Nous confronterons ensuite cette hypothèse à la clinique des adolescents en souffrance psychique en médiation théâtrale, au travers d’un cas. Cela nous permettra d’interroger plus loin cette dynamique paradoxale où jouer à être un autre amène à se sentir sujet.
Le narcissisme primaire, le double et l’altérité
Authors: Jung Johann
Published: November 2015

Les débats actuels sur le narcissisme primaire, alimentés par les récentes découvertes des neurosciences et de la psychologie du développement, obligent à repenser plus finement son inscription métapsychologique. À partir de ces recherches, l'auteur fait l'hypothèse d'un narcissisme primaire traversé par deux courants, l'un tourné vers l'objet, l'autre vers le sujet. Cette double vectorisation du fonctionnement psychique précoce suppose la nécessité d'un investissement de l'objet en double, progressivement construit comme « même et différent de soi ». Cette trajectoire permet de décrire les formes d'altérités qui accompagnent la subjectivité au cours de la construction du narcissisme et de l'identité.
De la responsabilité au processus de responsabilisation chez le sujet, mineur de justice
Authors: Winter Anne , Hirschelmann-Ambrosi Astrid
Published: November 2015

La sécurité alimente les débats depuis la fin des années 1990 en France. En ce contexte, le problème que soulève la délinquance des mineurs est exemplaire. Un leitmotiv émerge : la responsabilité. Or, elle n'est pas la responsabilisation. La subjectivité de l'adolescent est à considérer. Après un retour sur l'usage du concept de responsabilité et au moyen d'un exemple clinique, les auteurs rendent compte des conditions du processus de responsabilisation chez les sujets mineurs de justice et posent les prémisses d'une position à occuper en tant que professionnels en charge du suivi socioéducatif et judiciaire ou thérapeutique de ces adolescents.
Malebranche mort ou vif
Authors: Pellegrin Marie-Frédérique
Published: November 2015

Introduction aux articles du fascicule. En mobilisant les Entretiens sur la mort de Malebranche, on montre que célébrer sa mort, c’est constater ce que signifie la vie véritable selon lui : « La mort qui nous ferme les yeux, nous ouvre l’esprit. »
Il filosofo e la sua famiglia. Contributo alla storia di Malebranche vivant
Authors: Gori Giambattista
Published: November 2015

En laissant pour une fois de côté les témoignages traditionnels, l’article dessine un tableau inédit de la formation de Malebranche par les multiples relations religieuses, politiques, intellectuelles du lignage. Points de repère : Bérulle, controverse mathématique de teneur cartésienne ; Parlement et milieu parisien, querelle sur les Provinciales , bibliothèque de famille.
Le plaisir et la grâce chez Malebranche
Authors: Geny Vincent
Published: November 2015

Parmi les paradoxes de la philosophie de Malebranche, on remarque la manière étonnante, pour un philosophe chrétien, avec laquelle il traite la question du plaisir, considéré comme motif premier des déterminations des mouvements de l’âme. En quel sens le plaisir, tel que le sentiment intérieur en découvre la nature, détermine-t-il la réflexion de Malebranche sur la nature et sur la grâce ?
Malebranche sur le terrain des théories contemporaines de la reconnaissance : un révélateur
Authors: Antoine-Mahut Delphine
Published: November 2015

Dans les théories contemporaines de la reconnaissance, Hegel est perçu comme un initiateur. Il est possible de mobiliser dans ce débat contemporain un participant inattendu : Malebranche. Du point de vue de l’histoire de la pensée philosophique, cette mobilisation montre qu’une approche politique et éthique des textes de Malebranche permet de repenser sa place dans cette histoire. Du point de vue des théories contemporaines de la reconnaissance, elle permet de problématiser la question centrale de la relation entre une approche normative et une description empirique du lien social, la priorité étant ici donnée à sa dimension psychologique. Pour le montrer, on met en regard les modalités et les enjeux de la référence à Hegel dans La Lutte pour la reconnaissance de Axel Honneth et les analyses de Malebranche dans les livres IV et V de De la recherche de la vérité.
La correspondance de Bergson à Joseph Segond
Authors: Vieillard-Baron Jean-Louis
Published: November 2015

Texte, présentation et annotations de 26 lettres ou cartes, pour la plupart inédites, adressées par Henri Bergson à Joseph Segond de 1911 à 1938.
Vygotski/Spinoza
Authors: Schwartz Yves
Published: November 2015

Commentaire sur l’article d’Yves Clot, « Vygotski avec Spinoza, au-delà de Freud » de la Revue philosophique , 2015-2.
La reconnaissance des compétences des travailleurs handicapés : une conceptualisation au service de l’action
Authors: Amoureux Pierrot , Mazereau Philippe
Published: November 2015

En exposant les principes de la reconnaissance des compétences des travailleurs handicapés, tels qu’élaborés depuis plusieurs années par le réseau Différent et Compétent, les auteurs établissent des liens entre des apports de la recherche et la pratique apprenante du réseau. L’ingénierie de formation à la reconnaissance des compétences, construite par le travail réflexif du réseau, atteste de la valeur heuristique de certaines approches théoriques des notions de compétence professionnelle et d’expérience de formation. Dans la dynamique du transfert de la reconnaissance des acquis de l’expérience vers les publics en formation initiale ou en insertion, le réseau rencontre la question de la formation aux compétences sociales mise en œuvre en formation initiale (socle commun) ou dans le champ du handicap psychique. Comment prendre en compte la dimension des compétences sociales, sans entrer dans une démarche de reconnaissance normative ? Telles sont les questions théoriques et éthiques posées par l’extension de la reconnaissance des acquis professionnels hors de son milieu d’origine, le travail protégé.
Do Current Policies and Practices for Prescribing Opioid Medications Solve Chronic Pain Problems?
Authors: Maldow David , Miller Norman S. , Matthews Alexandria
Published: November 2015

Despite the widespread prescribing of opioid medications for the treatment of chronic pain, there is little or no evidence for its efficacy. In fact, the studies show that long-term prescribing of opioid medications leads to significant morbidity and mortality. The Controlled Substance Laws define prescription opioids as dangerous and addicting medications. Despite the classification and scheduling of opioid medication, their prescribing continues to be common and adverse. Most importantly, there are few studies addressing the addicting properties that drive the high rates of prescribing and adverse consequences. It is a myth that most people treated with opioids never become addicted and that addiction does not develop if you are prescribing for pain.

[
Psychiatr Ann
. 2015;45(10):500–505.]
Using a Robotic Cat in Dementia Care: A Pilot Study
Authors: Gustafsson Christine , Svanberg Camilla , Müllersdorf Maria
Published: November 2015

The current study aimed to explore (a) reactions of individuals with dementia to an interactive robotic cat and their relatives’ and professional caregivers’ experiences, and (b) to measure usability in developing the care/treatment of individuals with dementia using interactive robotic pets. An intervention design in a pilot study using mixed methods was conducted in two stages: a quantitative single-case study (
n
= 4) and a qualitative interview study (
n
= 14). Results indicated less agitated behavior and better quality of life for individuals with dementia. Interviews showed positive effects by providing increased interaction, communication, stimulation, relaxation, peace, and comfort to individuals with dementia. The tested interactive robotic cat was also considered easy to use. There is an increased need for alternative/complementary forms of care to meet an increasing number of individuals with dementia. For some individuals with dementia, an interactive robot, such as a robotic cat, can increase well-being and quality of life. [
Journal of Gerontological Nursing
,
41
(10), 46–56.]
Optimizing Stability in Femoral Neck Fracture Fixation
Authors: Ye Ye , Hao Jiandong , Mauffrey Cyril , Hammerberg E. Mark , Stahel Philip F. , Hak David J.
Published: November 2015

Optimizing stability of femoral neck fracture fixation is important in obtaining a successful outcome. The mechanical problems and strategies for achieving optimal stability differ depending on patients’ age and degree of osteoporosis. Femoral neck fractures in younger adults usually result from high-energy trauma and have a vertical fracture pattern. Strategies for optimizing fixation stability in this group include placing additional screws at right angles to the fracture plane and medial buttress plate augmentation. In elderly patients, screw position relative to the intact cortical femoral neck bone is of critical importance. Additional strategies for optimizing fixation stability in this group include the concept of length stable fixation, use of adjunctive calcium phosphate cement, and use of novel fixed angle fixation implants. [
Orthopedics.
2015; 38(10):625–630.]
Anatomic and Reverse Total Shoulder Arthroplasty in Patients Older Than 80 Years
Authors: Triplet Jacob J. , Everding Nathan G. , Levy Jonathan C. , Formaini Nathan T. , O'Donnell Kevin P. , Moor Molly A. , Virraroel Leonardo D.
Published: November 2015

Anatomic total shoulder arthroplasty (TSA) and reverse total shoulder arthroplasty (RSA) are routinely performed in patients older than 80 years. Often unaware of the differences between the 2 procedures, patients may expect similar outcomes from these procedures. This article reports the outcomes of primary TSA and RSA in patients older than 80 years, with attention directed toward differences in outcomes between the procedures. The authors evaluated a consecutive series of patients who were at least 80 years old and were treated with primary shoulder arthroplasty and had a minimum follow-up of 2 years. Of these patients, 18 underwent primary TSA for osteoarthritis and 33 underwent primary RSA for rotator cuff tear arthropathy. Pain scores, function scores, and range of motion were evaluated preoperatively and at final follow-up. Perioperative and postoperative complications, transfusion rates, length of stay, and subjective satisfaction with the outcome were reported. In these patients, TSA and RSA were similarly effective in improving pain scores, functional scores, and range of motion measurements. Patients who had TSA reported significantly greater satisfaction with surgery and had superior American Shoulder and Elbow Society total and function scores, forward elevation, and external rotation, but similar net improvement from preoperative levels. Although no significant differences were shown in complications, length of stay, or requirement for transfusion, patients treated with RSA had higher rates of transfusion and postoperative complications. Both procedures were similarly effective treatments for patients older than 80 years and showed similar improvements in pain, function, and motion. Patients undergoing RSA were less likely to have good to excellent results, with higher complication and transfusion rates. [
Orthopedics.
2015; 38(10):e904–e910.]
Prediction of Clinically Significant Leg-Length Discrepancy in Congenital Disorders
Authors: Mishima Kenichi , Kitoh Hiroshi , Kadono Izumi , Matsushita Masaki , Sugiura Hiroshi , Hasegawa Sachi , Kitamura Akiko , Nishida Yoshihiro , Ishiguro Naoki
Published: November 2015

Leg-length discrepancy greater than 2 to 2.5 cm can potentially have an adverse effect on our walking and standing mechanisms and requires proper correction involving surgical treatment. However, for minor leg-length discrepancy in childhood, decision making for the indications for and timing of epiphysiodesis is difficult because of unpredictable final discrepancy. The purpose of this study was to analyze longitudinal changes of minor leg-length discrepancy in congenital disorders and to determine earlier predictive values for the clinically significant discrepancy. Twenty-one patients with congenital disorders who had minor leg-length discrepancy less than 2 cm at the first presentation were retrospectively evaluated. The patients were divided into 2 groups according to leg-length discrepancy at latest follow-up: the significant group (n=11) had 25 mm or more of leg-length discrepancy and the minor group (n=10) had less than 25 mm of leg-length discrepancy. The authors evaluated longitudinal changes of leg-length discrepancy within the first 10 years by mixed-effects regression model. All patients showed monotonically increasing leg-length discrepancy with age, except for 2 (neurofibromatosis type 1 and macrodactyly of the foot) who demonstrated fluctuating leg-length discrepancy. Mean annual rate of leg-length discrepancy change in the significant group was 2.1 mm across the first decade of life and was significantly larger than that in the minor group (difference in slope, 1.3 mm;
P
<.0001). In minor leg-length discrepancy associated with congenital disorders, the incidence of clinically significant leg-length discrepancy can be predictable by the annual rate of leg-length discrepancy change in the first decade of life. [
Orthopedics.
2015; 38(10):e919–e924.]
Gender Effect on the Outcome of Partial Medial Meniscectomy
Authors: Haviv Barak , Bronak Shlomo , Kosashvili Yona , Thein Rafael
Published: November 2015

Complex posterior horn tears of the medial meniscus are common. Previous reports performed statistical stratifications to address the influence of gender on outcome following arthroscopic partial medial meniscectomy with variable conclusions. The aim of this study was to compare the clinical results of arthroscopic partial meniscectomy of the knee between men and women with complex medial meniscal tear type while controlling for other variables that may affect outcome. This study compared groups of 86 men and 49 women who were followed prospectively using the Lysholm Knee Scoring Scale, the visual analogue scale, and patient’s satisfaction. Mean age at operation was 51 years and mean follow-up was 26 months. Mean Lysholm score improved from 69 preoperatively to 82.1 postoperatively (
P
<.001) in the male group and from 64.2 preoperatively to 73.5 postoperatively (
P
=.04) in the female group. At last follow-up, 68 (79%) men and 35 (71%) women stated that they were satisfied with the operation. In both groups, the severity of chondral lesions was found to be negatively correlated to the preoperative score. Women had more severe chondral lesions at arthroscopy than men. This comparative study showed no significant difference between men and women in terms of clinical improvement following arthroscopic partial meniscectomies of complex tear types in stable knees with intact lateral meniscus. Women had lower functionality pre- and postoperatively, which correlated with more severe chondral degeneration at surgery compared with men. [
Orthopedics.
2015; 38(10):e925–e928.]
Snapping Knee Syndrome of the Medial Hamstrings
Authors: Protzman Nicole M. , Conkle Sean B. , Busch Michael F.
Published: November 2015

Snapping of the medial hamstrings is a rare condition, with few cases reported throughout the literature. The snapping sensation reportedly occurs when a hamstring tendon passes over the medial tibial condyle, a muscle belly, or another tendon. The semitendinosus tendon is frequently involved, but concomitant involvement of the semitendinosus and gracilis tendons has also been described. Although the exact etiology remains unclear, authors have theorized that the condition results from a congenital malformation or degradation of the accessory tendinous expansions of the semitendinosus. Whereas most cases resolve with conservative treatments, select cases require surgical intervention. Both the distal surgical release and tendon harvest have proved viable surgical procedures, achieving symptom alleviation with minimal patient morbidity. In this article, a case of medial snapping hamstring tendons involving both the semitendinosus and gracilis tendons is reviewed. A 17-year-old African American girl presented with extreme pain and snapping on the posteromedial aspect of her knee was appreciated. Radiographs were ordered and showed no acute fracture, no acute dislocation, normal medial joint space, normal lateral joint space, and normal patellofemoral space. Conservative and surgical options were reviewed, and the patient elected to undergo harvest of the tendons. Four weeks postoperatively, the patient reported complete resolution of symptoms. To date, there has been no recurrence of symptoms. The authors hope to increase awareness of this condition and add to the existing body of literature. [
Orthopedics.
2015; 38(10):e940–e942.]