bluuebunny/crossref_metadata_2025 huggingface dataset:
Cuerpo melancólico, mente sin memoria, multitud sin libertad: tres aspectos de la mutatio en la filosofía de Spinoza
Authors: Benvenuto Rodrigo Miguel
Published: August 2023

El propósito de este artículo es analizar el pensamiento de Spinoza a partir de las posibles articulaciones que se presentan de la noción de mutatio. Dadas las resonancias físicas de este concepto y sus implicancias a partir del encuentro entre los cuerpos más simples y los cuerpos compuestos, establecemos tres aspectos que permiten pensar la mutación, su diferencia con la transición, y su vínculo con la conservación. En primer lugar, tomamos como base el análisis de la disposición melancólica y su afectación en el cuerpo y la mente a partir del ejemplo del rey Saúl que Spinoza aborda en el Tratado teológico-político (I, 3). En segundo lugar, analizamos la mutatio a partir del caso particular de amnesia que padece un cierto poeta español (en Ética, IV, prop. 39, esc.). Por último, planteamos la mutatio en sus aspectos políticos y los problemas que se plantean a partir de la conservación y mutación de la forma. En los tres casos encontramos una posibilidad de pensar la mutatio en consonancia con el proyecto spinoziano y la trama relacional en la cual se desarrollan estos conceptos fundamentales de su filosofía.
El pedido del perdón. Una propuesta para resolver una aporía en Hannah Arendt sobre el perdón y la banalidad del mal
Authors: De Arteaga Gallinal Santiago
Published: August 2023

El artículo propone una resolución a una aporía presente en el pensamiento de Hannah Arendt a propósito de la banalidad del mal y el perdón. La banalidad del mal implica una renuncia del agente a pensar, una despersonalización, de tal modo que no se puede sostener, en rigor, que haya persona: no hay un quién en la acción. El problema es que, para Arendt, el sentido mismo del perdón estriba en que se dirige a la redención de la persona de su pasado. Por tanto, la aporía de la banalidad y del perdón es que no hay a quién perdonar. La condición estructural-fenomenológica que permite el aparecer de la persona es el pedir perdón, en la medida en que solo el pedido da cuenta de la reconstitución de la persona en el pensar y la devuelve al espacio del aparecer que posibilita el emerger del perdón.
The Intentional Structure of Image: Attentive Meaning and Image Consciousness in Husserl’s Phenomenology
Authors: Scanziani Andrea
Published: August 2023

This article considers Edmund Husserl’s description of image consciousness from the viewpoint of the role played by attentive meaning (meinen) in the intention of the image subject. We argue that the intention of the image subject has to be interpreted in the sense of the attentive meaning as presented in the second part of Husserl’s 1904/5 lecture on Phenomenology and Theory of Knowledge. Attentive meaning performs 1) the segregation of a specific apprehension along with the attentive articulation of experience, and 2), as a formative and preferential function, it introduces a difference in the objective consideration. First, we explain the connection between apprehension, attentive meaning, and object; then, we clarify the relationship between apprehension and attentive meaning in image consciousness in the 1898 manuscripts and the 1904 lecture; finally, we set forth the motivation for the intending of the image subject on the basis of the image apprehension.
ESTUDO DE IMPRESSÕES DIGITAIS LATENTES E NOVOS REVELADORES POR PAPER SPRAY MASS SPECTROMETRY (PS-MS)
Authors: Gomes Francisco , de Pereira Claudio , Mariotti Kristiane , Pereira Thieres , dos Santos Nayara , França Hildegardo , Romão Wanderson
Published: August 2023

STUDY OF LATENT FINGERPRINTS AND NEW DEVELOPERS BY PAPER SPRAY MASS SPECTROMETRY (PS-MS). In the criminal sphere, it is extremely important to identify perpetrators of crimes based on latent fingerprints (invisible to the naked eye) revealed at crime scenes and their corresponding objects. The present work aimed to evaluate four synthetic analogues of curcumin as possible IDL developers, and to compare their results with those of carbon black developer, as well as to reach the most adequate parameters in the use of the LTQ and FT-ICR mass spectrometers with the paper spray ionization (PS) source to study the chemical composition of the endogenous substances contained in the IDL. For this, a 24-1 factorial design was developed, where it was verified that the distance and voltage factors were the most influential for the increase in the response of signals, in the analysis of latent fingerprints by PS. Among the detected substances we can mention around 20 fatty acids, and squalene. Finally, four potential developers, synthetic analogues of curcumin, were compared with carbon black developer. The revelation of latent fingerprints occurred efficiently, allowing the visualization of minutiae, such as bifurcation and end of line, making it possible to classify them, according to the Vucetich Fingerprint Classification System.
Role of Analytical Methods in Herbal Drug Discovery
Authors: Bhattacharya Kunal , Randhoni Chanu Nongmaithem , Kalita Ramen , Chakraborty Arup , Deka Satyendra , Bordoloi Ripunjoy
Published: August 2023

Nature contains a huge array of unique phytomolecules, many of which have
previously evolved into lead compounds and have been transformed into herbal
formulations or are currently undergoing clinical studies. Plant-based pharmaceuticals
account for 25% of all drugs on the market, either directly or indirectly. The herbal
drug sector has gotten a lot of attention in recent years, which has resulted in its
exponential rise. People increasingly prefer herbal treatments to synthetic drugs,
highlighting their safety and efficacy. Standardization of these herbal medications has
become a significant component of the process involved in herbal drug development,
not just for Asians but also for westerners, due to increased interest. The role of various
analytical methods, such as chromatographic methods, spectroscopic methods,
metabolomics, DNA barcoding, and so on, has been explored in this chapter. These
methods aid in not only authentication but also quality assurance during the herbal
medicine research process.
Role of Andrographolide and its Analogues in Colon Cancer
Authors: Nelson Vinod Kumar , Pedda Pullaiah Chitikela , Bose Penjuri Subhash Chandra , Birudala Geetha , Gundlapalli Swarnalatha , Ausali Saijyothi , Chinnappan Sasikala , Kanna Sandeep , Kanuma Venkataramana , Mahmoud Idriss Mohamed Omar
Published: August 2023

Colon cancer is the third most frequently occurring and second most death.causing disease in the entire world. Even though there is rapid development in the
treatment, there is a high increase in the death rate of colon cancer. The current
treatments available for colon cancer are not specific and are mainly associated with
numerous toxic effects. Hence, developing novel drug treatments with desired
characteristics to treat colon cancer patients is in huge demand. In case of novel drug
discovery for various kinds of dreadful diseases like cancer and neurodegenerative
diseases, medicinal and plant-derived components also play a significant role. Here, in
this review, we have chosen andrographolide, a potent bioactive compound that shows
multiple pharmacological actions such as anti-inflammatory, antiviral, antioxidant,
hepatoprotective and neuroprotective effects. In addition, it also shows anticancer
effects against various types of tumours along with colon cancer. In this review, we aimed to describe in detail the effect of AG and its analogues in colon cancer by
identifying its possible drug targets. Thereby, it develops a chance to qualify AG as a
novel drug candidate for colon cancer in the near future.
Experimental characterization and environmental impact of different grades of CRM-modified asphalt binders
Authors: Khasawneh M.A.
Published: August 2023

Abstract. The use of Crum Rubber Modifier (CRM) with asphalt binders improves their properties by reducing their temperature susceptibility; this improvement is dependent on the way CRM and binder react with each other. The CRM particles tend to absorb some oils from asphalt binder and swell, resulting in a higher viscosity and thus stiffer binder. This paper discusses the effect of adding CRM to asphalt binder by applying three different percentages of CRM on two asphalt binders, viz., 60-70 and 85-100. A total of 120 specimens were prepared to test their basic physical properties such as penetration, softening point, ductility, flash and fire points, and rotational viscosity. It was found that the physical properties of asphalt binder are influenced by the percentage of crumb rubber used. The modified asphalt binders with higher crumb rubber content have lower ductility and penetration number, but higher softening point and viscosity values. Thus, it could be expected that they will have improved rutting resistance and extended service life. Furthermore, different analytical methods were utilized to validate the experimental results. It was reported that only penetration displayed change in behavior between 60-70 and 85-100 asphalt binders. CRM Content was found to be influential on all performance-related physical tests. Finally, it was obviously shown that the combined effect of Asphalt-Types and CRM Content is statistically significant on softening point, ductility and rotational viscosity test results. The incorporation of CRM in asphalt mix has multiple environmental benefits as well. The energy saving coupled with other benefits including less cracking and maintenance makes rubberized asphalt very attractive and beneficial in highway construction. Rubberized asphalt technique reduced the environmental impact of highway construction by 5% to 10% compared to traditional practice.
Using powder metal gears in industrial applications- A review
Authors: Mohammed O.D.
Published: August 2023

Abstract. Due to the high performance, lightweight, competitiveness and net shape of the parts produced using sintered Powder Metallurgy (PM), PM-based products are used in different industrial applications. PM method offers high precision and repeatability, maximum material utilization, tailored shape properties, freedom of design, cost efficiency, and sustainability. These advantages are driving the ongoing demand for PM products and for the PM method as a good alternative to the conventional gear production methods. The use of PM is confirmed as an applicable technology for gear production. However, the strength and NVH characteristics of PM-products still require more investigation. In the current paper, the mechanical properties, strength and NVH characteristics are presented and discussed. The paper concludes based on the presented overview of the applicability of PM gears in the industry, further research investigation is needed on both the system and component levels to improve the durability and NVH behavior which are important for extending the PM parts’ application. Moreover, the sustainability aspects of powder metallurgy technology should be emphasized.
Finite electroelastic deformation of dielectric semilinear hyperelastic tubes
Authors: Fadodun O.O.
Published: August 2023

Abstract. This study examines the finite electroelastic deformation problem of extension and inflation coupling of dielectric semilinear hyperelastic tubes with closed ends under the influence of internal pressure, axial loads and radial electric field. The laws of thermodynamics and Coleman-Noll procedure are used to derive the electroelastic constitutive model of the tube. The solution of the consequent electromechanical field equations shows that the applied radial electric field associated with the equal and opposite charges on the electrode coated surfaces contributes to both internal pressure and axial loads of the closed tube. Furthermore, it is obtained that the stress propagation in dielectric semilinear hyperelastic solids is sensitive to the electric displacement field generated within the solids while the accompanying electric field interacts with the deformation of the solids. Finally, and among other things, the graphical illustration shows that the radial electric field generated within the tube increases with the increasing azimuthal stretch.
Bi-axial behavior of glass/epoxy pipe subjected to internal pressure
Authors: Mateen Mohammed Abdul
Published: August 2023

Abstract. Composite structures are considered as the auxiliary to the conventional metallic materials. However, a thorough understanding of the material behaviour is required to replace the materials in use with scientific evidence for design rather than the designing based on high safety factor. The behaviour of filament wound E-glass/epoxy pipes of different helix angles exposed to internal pressure are studied. The sample GFRP pipe of different helix angles namely [±45o], [±55o] & [±70o] were subjected to open end pressure until the sample failed due to burst(pressure) and the corresponding strains were recorded using the strain smart 5000 data acquisition system (DAQ). The theoretical first-ply failure and burst pressure were determined using (i) Maximum stress theory, (ii) Maximum strain theory and (iii) Tsai Hill theory and were later compared with the experimental results. The first ply failure of the samples was observed by the whitening phenomenon. Later, the damage initiated by the formation of pine holes that act as a micro crack and which later grows to a macro crack in the fiber direction until final failure. A nonlinear relation between the longitudinal stress and strain was observed.
One dimensional oedometer laboratory testing for expansive clay submerged with hydrocarbon fluids
Authors: Bani Baker M.
Published: August 2023

Abstract. Landfills are currently one of the most effective ways to dispose of waste. Underground storage tanks (UGST) are also used to store hydrocarbon fluids that include different types of fuels. The bottom part of the landfills and UGST is critical. This liner material and its composition prevent heavy metals and leachate from infiltrating the groundwater table. Failure of this layer presumably causes most landfill failures. Bentonite clay is used to build such liner because of its properties including high cation exchange capacity and swelling index. The swelling of bentonite is sensitive to the type of liquid and load. It swells under low loads when submerged with water and to a lesser extent for ethanol. However, it undergoes consolidation when penetrated by biofuel. Test results indicate that bentonite undergoes swelling in water under high load (40 kPa) and consolidates for both alternative fuels (biofuel and ethanol). Under very high loads (100 kPa) bentonite consolidates for all kinds of liquids including water.
Numerical simulation of high-pressure gas-jet impingement on the adjacent equipment
Authors: Jassim E.I.
Published: August 2023

Abstract. Cold jet is a result of a high-pressure leakage through a wall crack, valve stem, or any other opening caused by an accident or failure to a high-pressure device. The phenomena and its impact on the adjacent and surrounding equipment are simulated using Computational Fluid Dynamics (CFD) techniques. For the preliminary study, the working fluid used in the simulation is methane. The simulation is linked to appropriate thermal and fluid property estimation software using parameter-tuned equations of state to predict the real multi-component natural gas flow conditions. Through the simulation, a spot of condensation and/or nucleation was predicted. These spots are crucial since their effect appear on the jet simulation in which multiphase properties must be considered. The results showed that the temperature variation on the adjacent surface is divided into three regions, namely: vicinity of stagnation point, sharp variation region, and mild variation region. Such distribution results in inception of thermal stresses that could cause catastrophic incident if rapture occurs. Hence, wall thickness of the equipment that exposed to cold jet should be cautiously selected to sustain the extra thermal stress as well as localised non-uniform stress distribution as detailed in the Finite Element based coupled thermo-mechanical analysis.
Ultrasonic pulse velocity (UPV) and initial rate of water absorption (IRA) of foam concrete containing blended cement
Authors: SUNARNO Y.
Published: August 2023

Abstract. The adverse environmental effects caused by cement production activities could be minimized by reducing the use of cement in the concrete mix, replacement with eco-friendly materials, and making low-unit weight cement-derived products. During the cement production activities, fly ash can also be used by mixing it in form of Portland Composite Cement (PCC)/blended cement products or directly in the concrete mixing process. Furthermore, in low-unit weight concrete, foam concrete is usually obtained using an agent that forms random air bubbles in the cement paste and is applied in construction according to its structural function. Therefore, this research aims to study and analyze the correlation between unit weight and non-destructive tests (NDTs) value on foam concrete with variations in the use of cement, namely OPC, PCC-1, PCC-2, and OPC+FA. The quality of the foam concrete was evaluated by non-destructive tests, there are Ultrasonic Pulse Velocity (UPV) and Initial Rate of Water Absorption (IRA). The results show that UPV value of all specimens is directly proportional to its unit weight and varied inversely to the IRA value.
Linear response of thin axysimmetric cross-ply structure under a static load: Numerical and analythical comparisons
Authors: Saputo S.
Published: August 2023

Abstract. Thin-walled mechanical components, such as beams, plates and shells, are widely used as structural components in several engineering fields, in particular mechanical, aeronautical and aerospace sectors. The purpose of this work is to analyse the cross-ply bending behaviour of cylindrical and spherical shell structures using the finite element method. Hence, numerical models, realized using commercial software, were realized using the shell and solid approaches and were compared with numerical and analytical methods to appreciate their advantages. In this research, a Navier solution in close form for high-order theories, developed using the Carrera Unified Formulation (CUF) approach, has been reported, where the high-order elastic shell model has been developed using the variational principle of virtual work for three-dimensional linear theory equations and the analytical results were obtained using the Mathematica software. The results furnished by the numerical method such as the elasticity solutions given in the literature using Navier’s method are used as a benchmark for comparing the finite element method results in terms of maximum displacement and stress distribution along the principal structure direction. However, the numerical shell model cannot provide sufficient data to describe the tensional and deformational state at all points and especially along the laminate thickness. Wishing to obtain a complete description of the plate's mechanical behaviour, it is necessary to use a three-dimensional approach with the associated increase in calculation time. In contrast, the numerical solution based on the CUF approach shows a very efficient description of the composite structure behaviour and its use should be preferred to the classical lamination approach if an accurate description of the structure is necessary.
Utilizing machine learning techniques for predictive modelling of absorptivity in l-shaped metamaterials
Authors: Adil M.
Published: August 2023

Abstract. Metamaterials are artificially engineered materials that have properties not found in naturally occurring materials. They are designed to have specific electromagnetic or other physical properties, such as negative refraction, superconductivity or high absorptivity. They are often composed of structures on a scale much smaller than the wavelength of the phenomena they are intended to manipulate. Metamaterials have a wide range of potential applications, including in antennas, cloaking devices, and super resolution imaging. In this paper we have simulated and validated an L shaped meta material to make a data set of its absorptivity by varying different input parameters and then used these data to predict the absorptivity of any L shaped metamaterial using machine learning and it gave satisfactory results.
New approach for modeling randomly distributed CNT reinforced polymer nanocomposite with van der Waals interactions
Authors: Caliskan U.
Published: August 2023

Abstract. In this paper, using molecular and micromechanics methods, a new approach for the prediction of the stiffness of randomly distributed CNT/polymer nanocomposites with the van der walls interactions is presented. A multi-scale modeling technique was designed for CNT nanoparticles randomly embedded in the polymer using AMBER force field. This multi-scale model constitutes a representative volume element. The representative volume element consists of polymer, CNT nanoparticle, CNT-polymer interfacial region and van der waals bonds. A programming code was developed that randomly distributes nanoparticles according to the desired volume fraction. Python scripting language was used for the modeling technique performed in a finite element environment. By modeling the interfacial regions around randomly distributed CNTs, van der Waals bonds are modeled stochastically. In this study, the subject of interest is the number of CNTs positioned in the RVE according to the volume ratio. These numbers were determined at the level allowed by finite element equations and computational solvers and their effects were investigated by calculated stiffness behavior.
Artificial intelligence-based prediction of geotechnical impacts of polyethylene bottles and polypropylene on clayey soil
Authors: Baghbani A.
Published: August 2023

Abstract. This study aims to investigate the application of artificial intelligence (AI) methods in predicting the resilient modulus of soil mixtures with polyethylene (PE) bottles and polypropylene (PP). The AI methods used in the study are artificial neural network (ANN) and classification and regression random forest (CRRF), and the modeling was conducted using a database of 160 datasets. The study also evaluated the importance of different input parameters on the accuracy of the models. The results show that the CRRF model is more accurate than the ANN model in predicting the effects of materials PE and PP on soil resilient modulus. Additionally, the study found that the number of hidden layers and neurons in the ANN model should be optimized for the best performance and increasing their number does not always lead to increased accuracy. Finally, the study identified the most and least important input parameters for predicting the effect of PE and PP on the resilient modulus of the mixture using both AI models.
Structural and environmental safety study of the holy mosque area using CFD
Authors: Farouk M.
Published: August 2023

Abstract: A CFD model was developed, covering a square area of 3.64 km2 and comprising the Holy Mosque near its center, the actual terrain, and the main buildings surrounding the Mosque. The gust wind effects on the existing cranes, the comfort of the pedestrians, and the air quality were studied for the first time in this Holy area. The air quality in this study was related to calm speed and creating a fertile environment for spreading infectious diseases. The study revealed that wind comfort levels are achieved in nearly all selected locations. Also, the wind speeds are generally low in the area. However, gusting wind currents appeared from limited directions, causing more wind loads on cranes. It is recommended to finalize some cranes' work shortly in specific locations or change their places, lower the crane boom at rest, and stop working on windy days. The air quality in some locations may be considered relatively poor. New tall buildings surrounding the Holy Mosque from the North and the East are not recommended except after studying their impacts on the air quality. Pruning North and/or East Mounts can remarkably improve natural ventilation. Large-scale fans are a solution after detailed study and simulation.
Analyzing the electromagnetic forming process of SS304 sheet using AA6061-T6 driver through a fully coupled numerical model and experimentally validation
Authors: Khan Z.
Published: August 2023

Abstract. Driver-based electromagnetic forming (EMF) is a process that uses electromagnetic forces to form metal components into a desired shape. The process involves the use of a conducting driver metal, which is driven by an electromagnetic coil that generates a high-frequency, high-amplitude current. The driver sheet pushes the nonmagnetic sheet metal workpiece against a die causing it to be deformed into the desired shapes. EMF is particularly useful for forming complex shapes and for creating precise forms with minimal material loss. Applications of EMF include the formation of aerospace and automotive components, medical devices, and other products that require precise shaping and minimal material waste. This research focuses on the driver-based electromagnetic forming of Austenitic Stainless Steel (SS304) sheets using Aluminum alloy (AA6061-T6) as a driver. The analysis includes the numerical results of the magnetic field, Lorentz force, sheet deformation and velocity at four points on the sheet profile. The study also compares the numerical results to experimental measurements of the sheet profile. The study found that the numerical results were in good agreement with the experimental results.
Biopolymers and their Application-Oriented Composites into a Circular Economy Context
Authors: Teijido R.
Published: August 2023

Society is increasingly concerned about environmental problems derived from the inappropriate use of polymeric materials and their inefficient recycle. Furthermore, considering that petroleum is not an endless raw material, the search for new sustainable materials has been gaining great interest in recent years. These materials should not only be sustainable but also fulfil the requirements requested by the industry. In this context, biopolymers stand out for their natural origin and their potential to substitute some of the synthetic polymers. On the other hand, the design of new composites capable of adapting and responding to the increasingly sophisticated applications presented by this new era of additive manufacturing or the internet of things is crucial. Moreover, the new business horizons related to the implementation of industry 4.0 require the development of complex sustainable materials for their development but considering a Circular Economy and sustainability perspectives.
Recent Advances in Polymeric Systems for CO2 Capture: A Small Catalogue
Authors: López-Gallego R.
Published: August 2023

The advances in terms of new materials used for CO2 collectors are growing due to the necessity to reduce the greenhouse gases emission and to respond to the environmental regulations. There are multiple systems which have shown remarkable properties for removal of specific pollutants. Nevertheless, the necessity of developing devices more effective, specific and with higher yield is necessary to reach net zero emissions by 2050. The use of polymeric matrices for CO2 capture purpose is growing due to the versatility of these materials together with their low cost, regarding in comparison to other systems. There are multiple advances in terms of CO2 collectors, and specifically for membranes due to the possibility to modulate these polymers and their properties, but also because these can be combined with other materials thus increasing the possibilities of their applications. This chapter shows some of these recent advances attending to the permeability of these materials, as one of the most important materials with unique characteristics studied for CO2 capture.
Advances in the Treatment of Waste Derived from Electronic Components: The Future of Cars: An Assessment through Raw Materials
Authors: Ortego A.
Published: August 2023

A conventional car needs more than 50 different types of metals, being critical most of them. In addition, the renovation of current cars for cleaner, safer and more comfortable ones will increase the critical metal demand to manufacture some components: batteries, LEDs for lighting, permanent magnets for motors, electronic units and different kinds of sensors. As a result, the availability of enough raw materials is a matter of concern for the automobile industry so new approaches from resource efficiency must be urgently applied. This chapter presents a review of the car´s resource efficiency from those metals needed to be manufactured with special attention to those used in electronic components. To accomplish with this purpose, three main goals have been established in this study: (1) analyzing car compositions and the most strategical metals for the automotive industry, (2) examining possible raw material bottlenecks before 2050, and ultimately (3) studying the effectiveness of current recycling policies and alternatives from eco-design.
Aprendizagem da Docência em Pesquisas Originárias de Publicações de Países de Língua Inglesa
Authors: Farias Isabel Maria Sabino de , Lima Cunha Marcel , Duarte Guimarães Marília
Published: August 2023

Aprendizagem da docência é um conceito que, no Brasil, possui expressiva difusão na área da educação, tematizado sobretudo com esteio em referências ibéricas. Argumenta-se que o debate nacional carece de pesquisas advindas de países de língua inglesa. Questionamos: o que se produz sobre aprendizagem da docência em países de língua inglesa? Quais as principais referências desse debate nesses contextos? A produção científica desses países é escassa quando se trata dessa temática? Em busca de pistas elucidativas para essas indagações, realizamos uma revisão sistemática na base de dados ERIC com o objetivo de mapear as produções sobre aprendizagem da docência advindas de países de língua inglesa. Os resultados apontam a existência de um importante debate relacionado ao assunto em países de língua inglesa, com significativa atenção para professores iniciantes. Utilizando apenas a palavra-chave Learning to teach associada ao descritor Beginning teacher chegamos a 24 artigos revisados por pares. Há necessidade de conhecer mais detalhadamente a produção dos países de língua inglesa, identificando aproximações e distanciamentos em relação a produção brasileira.
Itinerários de Pesquisas com Professores Iniciantes
Authors: Ciríaco Klinger Teodoro
Published: August 2023

Analiso neste texto o itinerário de três estudos que tiveram, no cerne dos seus objetivos, a preocupação em compreender processos de iniciação profissional em diferentes níveis de ensino. As pesquisas foram desenvolvidas a partir de reflexões e ações do Grupo de Estudos e Pesquisas "Nome do Grupo" (SIGLA/CNPq) vinculado à Universidade "Nome da Instituição", Campus XXXX. O enquadramento teórico abarca questões do campo da formação inicial, problemas e perspectivas dos primeiros anos da carreira. A metodologia empregada foi a pesquisa qualitativa, de caráter descritivo-analítico, em que foram adotados questionários, narrativas escritas, como também a entrevista semiestruturada. Os resultados indicam que a fase de indução dos professores precisa ser encarada como um projeto coletivo, no sentido de que o jovem docente necessita ter o apoio tanto da escola quanto de seus colegas mais experientes para "sobreviver" o início de sua atividade profissional.
Da Inserção Profissional à Perseverança Docente
Authors: Damasco Denise Gisele de Britto , Passos Laurizete Ferragut
Published: August 2023

O artigo  discute  a trajetória profissional de docentes do Distrito Federal em um estudo longitudinal visando compreender suas aprendizagens docentes e profissionais. Há dois contextos de pesquisa, sendo o primeiro realizado entre 2010 e 2014 (pesquisa doutoral) e o segundo contexto cerca de dez anos depois (pesquisa de pós-doutoramento). A inserção profissional e a perseverança na carreira docente constituem o quadro teórico, destacando a contribuição da pesquisadora Joséphine Mukamurera e de pesquisadores do contexto francófono sobre essa temática. Buscamos as aproximações metodológicas entre o Método Documentário e o método Análise de Prosa na compreensão de trajetórias de profissionais do DF, tendo em vista que os dois métodos de análises foram utilizados, para compreender as trajetórias dos docentes. As análises e interpretações evidenciam que não há um modelo de inserção profissional, que a perseverança não depende apenas de formação continuada que se realiza ao longo da carreira, do sentimento de êxito no início da carreira, havendo inúmeros fatores que complexifica a profissão docente, dentre os quais as condições de trabalho e outras condições subjetivas inerentes a ele.
Narrativas de Futuras Professoras Indígenas Kaingang
Authors: Silva Ivone Maria Mendes
Published: August 2023

Este artigo discute como futuras professoras indígenas aprendem a ensinar, considerando as experiências e conhecimentos da docência que constroem em contextos diversos, bem como os desafios enfrentados no processo. Para tanto, analisam-se as narrativas produzidas, em entrevistas individuais e grupal, por cinco licenciandas Kaingang que estudam em uma universidade pública rio-grandense. Entre os resultados destacam-se as reflexões por elas produzidas sobre a importância da interculturalidade na ação pedagógica e a relação, por vezes conflituosa, que mantêm com a cultura escolarizada e os conhecimentos científicos. O reconhecimento positivo da profissão docente em suas comunidades, aliado às contribuições sociais, políticas e epistêmicas que ela tem ajudado a produzir por meio dos professores indígenas com quem convivem e delas próprias, motivam-nas a investir na educação escolar como um instrumento de luta política por direitos e de concretização de aspirações individuais e coletivas.
The Role of Internal and External Individual Difference Factors in Bilingual Development: Exploring Highly Proficient Kurdish-English Bilinguals’ Perceptions
Authors: Faraj Ismael Rafaat , Hamid Twana Saadi
Published: August 2023

Drawing on qualitative research, the present study examines the characteristics of seven highly proficient Kurdish-English bilingual adolescents and their perceptions of the role of individual difference factors in bilingual development. Adopting a deductive thematic analysis approach, the collected data from semi-structured interviews were analyzed. The findings indicate that special attention should be paid to both internal and external factors in order for Kurdish-English bilinguals to reach high level of proficiency in both languages. External factors of richness of input, input quantity, language output, and socioeconomic status are crucial for fostering morphosyntactic and lexical skills in Kurdish and English. Moreover, the bilingual learners stated that conducting mathematical and logical problem-solving activities frequently and having high level of language learning aptitude are important predictors of rapid development of bilingual language abilities. In terms of age effects, the bilingual adolescents conveyed that having younger age and earlier start to Kurdish and English learning always lead to better morphosyntactic and lexical outcomes in both languages. To the best of our knowledge, the current study is the first to explore the role of individual difference factors in bilingual development among highly proficient Kurdish-English bilinguals. The paper highlights implications and directions for further research.
Targeted Glioblastoma Treatment via Synthesis and Functionalization of Gold Nanoparticles With De Novo–Engineered Transferrin-Like Peptides: Protocol for a Novel Method
Authors: Müller Fiedler Augusto , Medeiros Michelle , Fiedler Haidi Dalinda
Published: August 2023

Background

Glioblastoma multiforme (GBM) is an aggressive brain tumor with limited treatment options due to the blood-brain barrier’s (BBB’s) impedance and inherent resistance to chemotherapy. Gold nanoparticles (AuNPs) functionalized with transferrin-like peptides show promise in overcoming these challenges, enhancing drug delivery to the brain, and reducing chemotherapy resistance.

Objective

The primary goal of this study is to establish a detailed protocol for synthesizing and stabilizing AuNPs, functionalizing them with de novo–engineered transferrin-like peptides, and conjugating them with the chemotherapeutic agent temozolomide. This strategy aims to improve drug delivery across the BBB and circumvent chemotherapy resistance. The secondary objective includes an assessment of the safety and potential for in vivo use of the synthesized nanoparticle complex.

Methods

The proposal involves multiple steps with rigorous quality control of AuNP synthesis, stabilization with surfactants, and polyethylene glycol coating. The engineered transferrin-like peptides will be synthesized and attached to the AuNPs’ surface, followed by the attachment of temozolomide and O6-methylguanine-DNA methyltransferase inhibitors. The resulting complex will undergo in vitro testing to assess BBB penetration, efficacy against GBM cells, and potential toxicity.

Results

Initial preliminary experiments and simulations suggest successful synthesis and stabilization of AuNPs and effective attachment of transferrin-like peptides. We propose peptide attachment verification using Fourier transform infrared spectroscopy and surface plasmon resonance. Additionally, we will conduct pH stability tests to ensure our functionalized AuNPs retain their properties in acidic brain tumor microenvironments.

Conclusions

The proposed functionalization of AuNPs with de novo–engineered transferrin-like peptides represents a novel approach to GBM treatment. Our strategy opens new avenues for drug delivery across the BBB and chemotherapy resistance reduction. While we primarily focus on in vitro studies and computational modeling at this stage, successful completion will lead to further development, including in vivo studies and nanoparticle design optimization. This proposal anticipates inspiring future research and funding in neuro-oncology, presenting a potentially innovative and effective treatment option for GBM.

International Registered Report Identifier (IRRID)

RR1-10.2196/49417
Detection of AtRKD4 Gene and Induction of Somatic Embryo in Transformant of Phalaenopsis amabilis Carrying 35S::GR::AtRKD4
Authors: Sundari Dika , Perdana Naufal Ghozi Aditya , Mose Windi , Gutierrez -Marcos Jose , Semiarti Endang
Published: August 2023

Phalaenopsis amabilis (L.) Blume is a native Indonesian orchid that plays an important role in the breeding of orchid’s hybrid worldwide. The high consumer demand causes a decline in the population of orchids for commercial trade. Plant propagation through induction of somatic embryogenesis will be very beneficial, because plants can be obtained in large numbers and uniform. AtRKD4 gene is an important gene in the model plant Arabidopsis thaliana which functions very early in development stage to initiate embryo formation. The AtRKD4 gene has been inserted into the P. amabilis orchid and several transformants have been obtained. This study aims to determine the stability integration of the AtRKD4 gene in the transformant P. amabilis genome and induce somatic embryo formation on transformant orchids. Plantation of leaf explants from P. amabilis transformants on hormone-free New Phalaenopsis basic medium induced somatic embryo formation by 20%.  Anatomical analysis showed that there is no difference stage between anatomy of somatic embryo development pattern in P. amabilis transformant and somatic embryo development pattern of monocot plants in general, PCR analysis using AtRKD4 specific primers showed that the embryos still contained 198 bp fragments of the AtRKD4 gene. In conclusion, the AtRKD4 gene is stably integrated in the P. amabilis orchid genome and can continuously induce the formation of somatic embryo from somatic cells of orchid transformants.
DNA Authentication of Indonesian Leaffish Pristolepis grooti from Kelekar River and Ogan River in South Sumatra Based on Cytochrome C Oxidase Subunit I (COI) Gene
Authors: Syaifudin Mochamad
Published: August 2023

Indonesian leaffish Pristolepis grooti, an endemic species, are distributed in the region of Sumatra, Riau, Bangka Belitung and Kalimantan. However, there has been a decline in the population recently. This research purposed to investigate the mitochondrial DNA cytochrome c oxidase subunit I (COI) gene, the genetic distance, the genetic tree of the leaffish and characterize the chemical physics of water of its habitat in the Kelekar River Muara Enim Regency and the Ogan River, Ogan Ilir Regency. The method used in species authentication was DNA isolation, amplification using PCR (Polymerase Chain Reaction) and sequencing of COI gene. The size of the COI mtDNA gene fragment was 704 bp (PM 1, PM 4, PP 2 and PP 4) and 723 bp (PM 2, PM 3, PP 1 and PP 3). A cryptic diversity of the species P. grooti is found based on the genetic distance value of 4.5-6%, both in the Kelakar and Ogan Rivers. The phylogenetic tree of the leaffish of this study formed 2 separate sub-clusters with a bootstrap value of 50%. The properties of water qualities in the two rivers included temperatures 28.3-31.8°C, pH 5.6-8.3, dissolved oxygen 4.82-10.89 mg L-1, alkalinity 10-28 mg L-1 CaCO3, water transparency 16-45 cm, ammonia 0.47-0.70 mg L-1, water current 0.17-0.30 m s-1 and TDS 7-44 mg L-1.
Diversity and Distribution of Ficus (Moraceae) in The Karst Ecosystem of Bantimurung Bulusaraung National Park
Authors: Yelastri Yelastri , Sulistijorini Sulistijorini , Djuita Nina Ratna
Published: August 2023

Bantimurung Bulusaraung National Park is an area that has the largest karst ecosystem in Indonesia. Karst is prone to damage and difficult to reuse, so it requires conservation efforts. One of the plant species that can maintain this sustainability is Ficus which acts as key species in karst ecosystems. However, at this time the species is experiencing disturbances, one of which is due to the experience of invasive plants that can threaten the existence of Ficus because the weeds can colonize habitats and are dominant which can change species diversity. This study aimed to analyze the diversity and distribution of Ficus, compare species composition, and analyze environmental factors that affect Ficus spp. in Pattunuang Resort and Bantimurung Resort. Vegetation analysis method with nesting plots placed by purposive sampling and supported with environmental and soil data measurements to determine the factors that indicate the habitat preference of Ficus. We found 18 plant species of Ficus spp. in total. At Resort Pattunuang we found 14 Ficus species with the highest abundance being Ficus sundaica (27.55%), while we recorded 15 Ficus species at Resort Bantimurung with the highest abundance being Ficus ampelas (29.23%). Ficus species were uniformly distributed with a relatively high ratio of species composition in both resorts. Principal Component Analysis (PCA) showed that the presence of Ficus in Pattunuang Resort is influenced by wind speed, soil temperature, air temperature, soil moisture, soil pH, and air humidity. In Bantimurung Resort, the existence of Ficus is influenced by wind speed, soil temperature, soil moisture, and air humidity.
Autecology of Nepenthes spp. in Peat Swamp and Heath Forest Pematang Gadung, West Kalimantan
Authors: Utari Nofi , Sulistijorini Sulistijorini , Ariyanti Nunik Sri
Published: August 2023

Nepenthes occur in various habitat types in West Kalimantan. But some species are categorized as vulnerable on the IUCN red list. Autecological studies of Nepenthes spp. are required for species management and conservation. The study aimed to analyze species diversity, distribution pattern, association, and environmental factors that correlated with Nepenthes spp. at peat swamp and heath forest in Pematang Gadung. Data was collected in September 2021 by purposive sampling on 60 plots measuring 3 x 3 m2 in each habitat type. Species diversity was analyzed based on the presence and abundance of species in the plots. The distribution pattern was determined using a standardized Morisita index (Ip). Meanwhile, the association type was determined based on the Jaccard index (JI). Environmental data were analyzed by Canonical Correspondence Analysis (CCA) using Past Version 4.03. This study found six wild species in a peat swamp and four species in a heath forest. The population of Nepenthes spp. has clumped distribution pattern with Ip>0. Nepenthes spp. are associated with plants such as Barringtonia racemosa, Syzygium sp., Nephrolepis biserrata, and Campnosperma auriculatum. The result of CCA revealed that environmental factors in both habitat types affected the presence of each Nepenthes species. The air temperature, humidity, soil moisture, and light intensity show different influences on different species.
HEMATOHIDROSIS-A RARE BLEEDING PHENOMENON
Authors: GOURU GUNA , SNEHA B. , PRASAD T. S. DURGA
Published: August 2023

Hematohidrosis is a rare clinical condition in which an individual sweats blood. Even though there are several causes, such as systemic diseases, vicarious menstruation, extreme physical activity, psychogenic reasons, and idiopathic causes, acute fear and intensive mental pondering are the most frequent. Bloody perspiration, bloody tears (Hemoclaria), bleeding from the nose, bleeding from the ears (Otorrhoea), and leaking blood from various skin surfaces are all indications and symptoms of this condition. Here, we present a case of hematohidrosis in a 9y old female child with bleeding for two months from her forehead, nose, ear, and vagina, who responded to propranolol.
Lipid bilayer-coated nanoparticles: mimetism for biomedical applications
Authors: Magallanes-Puebla Alejandro , López-Marín Luz María
Published: August 2023

Living organisms are made of self-assembled nanostructures. Therefore, the control of sizes, shapes, textures, or chemical functions during chemical synthesis, as managed by nanotechnology, leads to a myriad of possibilities in the field of biomedical applications. One of the main approaches in this area, also known as nanomedicine, is the production of biomimetic nanoparticles, which take profit from either natural products or bioinspired materials. Cell-cell communications are strongly dependent on molecular arrays displayed at the cell surface in the context of lipid bilayers. Therefore, the mimicry of such coatings has gained great interest during the last decades. Herein we summarize the rationale and the methodologies related to this approach, with a special focus on the delivery of drugs and vaccines. The challenges and opportunities in this area, along with some selected examples will be discussed as well.
Incapacidad no es lo mismo que discapacidad
Authors: Fortoul Teresa I.
Published: August 2023

They had physical deformations and were called phenomena or monsters and were often exhibited as shows in tents or circuses. The life, work and struggles of this artist with a disability, invites us to reflect and formulate commitments to understand disabilities: physical, visual and auditory, intellectual and visceral that present 15% of the world population and generate empathy to be more inclusive with them.