bluuebunny/crossref_metadata_2025 huggingface dataset:
Las modernidades, la psicopolítica y el sistema penal. Una mirada desde Black Mirror
Authors: Ávila Santamaría Ramiro
Published: April 2023

El mundo de las tecnologías digitales ha copado nuestras rutinas y aún no somos conscientes de sus efectos. Podemos percibir algunos destellos por los escándalos del tipo Facebook, los datos personales y su influencia en los procesos electorales1 , o los hackeos a escala global, algunos de ellos publicados por WikiLeaks, que demuestran el nivel de opacidad de nuestras democracias que torturan, trafican con armas, organizan guerras y aún más, a nombre de nuestras libertades, con nuestros votos e impuestos. En el ámbito individual, para nadie es ajeno cómo en las calles, lugares de comida, mesas familiares, aulas de clases, transportes públicos, las personas están completamente conectadas y dependientes de un aparatito que conocemos como smartphone. Estamos conectados con millones de personas por las redes sociales y, al mismo tiempo, paradójicamente, desconectados de las personas que están cerca.
La amistad germinal : la participación chilena en la independencia del Perú
Authors: Orrego Penagos Juan Luis
Published: April 2023

En el presente trabajo revisaremos en qué momento Chile se involucró en los planes de San Martín respecto a la liberación del Perú. Para ello veremos los antecedentes, es decir las dificultades del gobierno de Buenos Aires de atacar al Perú por la actual Bolivia, y la creación del Ejército de los Andes en Mendoza. Pasaremos por la Independencia de Chile y nos centraremos en los esfuerzos del gobierno de O’Higgins por financiar la guerra patriota en el Perú.
Una convivencia reanudada : exilios e intercambios culturales y políticos entre Chile y Perú (1920-1940)
Authors: Moraga Valle Fabio
Published: April 2023

Chile peleó su última guerra internacional hace 120 años. Pese a ello, ha mantenido una fama de país «belicoso» hacia sus vecinos desde el mismo día en que se terminaron las acciones armadas, tanto en los territorios de Perú como de Bolivia. Desde esa lejana fecha del siglo XIX, Chile nunca más empuñó un arma contra países vecinos. La fama de «país guerrero» y «usurpador» se debe, más bien, a que el término formal de las hostilidades —en 1904, con Bolivia y en 1929, cuando se firmó el Tratado de Lima— tardó mucho tiempo en definir la frontera definitiva y durante 46 años mantuvo ocupado territorio peruano sin que se resolviera diplomáticamente los límites definitivos entre ambos países.
En la rebeldía hermanos : confluencias peruano-chilenas en las luchas sociopolíticas latinoamericanas (siglos XIX y XX)
Authors: Vallenas Hugo
Published: April 2023

Los mejores momentos de amistad y colaboración entre peruanos y chilenos han tenido como protagonistas a las juventudes rebeldes de ambos países, y ocurrieron cuando la libertad estuvo restringida o amenazada en alguna de las dos naciones. «Tumba serás de los libres o el asilo contra la opresión», dice el himno nacional chileno. Esta función la cumplió tanto Chile como el Perú, según la situación política, para varias generaciones de inconformes y conspiradores que se dieron la mano desde uno y otro lado de la frontera peruano-chilena, por lo menos desde fines del siglo XVIII.
Devociones compartidas. El culto a Santa Rosa y al Señor de los Milagros en Lima y Santiago de Chile (siglos XIX y XX)
Authors: Rosas Lauro Claudia
Published: April 2023

En el presente trabajo buscamos realizar un recorrido de estos dos cultos emblemáticos de Lima y el Perú. Ambos tienen una historia propia que se remonta a la época virreinal peruana y que forman parte de su identidad nacional, en este sentido analizaremos su origen, desarrollo histórico, recepción e importancia en ambos países, desde una perspectiva de larga duración —tal como diría Fernand Braudel—, buscando establecer elementos que aporten a futuras lecturas de su aporte a la integración binacional.
Isidoro Gamarra Ramírez : un tarapaqueño sindicalista en Lima
Authors: Troncoso Rosa
Published: April 2023

La figura de Isidoro Gamarra Ramírez tenderá a agigantarse con el paso de los años. Por sus décadas como secretario general de Confederación General de Trabajadores del Perú (CGTP), sus años en prisión durante el gobierno de Sánchez Cerro, su actividad sindical y política, pero sobre todo su carácter afable y determinado, la historia social peruana lo reivindicará y lo ubicará entre los grandes sindicalistas latinoamericanos del siglo XX. Su opción por la lucha social y política le negó una familia propia, aunque murió rodeado de los suyos en el Callao, en las proximidades de la urbanización Tarapacá. Nadie que haya estudiado la historia social peruana del siglo XX podría desconocer el nombre de Isidoro Gamarra. Sin embargo, en Chile es un desconocido hasta para los especialistas, a pesar de que siempre Tarapacá ocupó un lugar en su memoria y en su corazón. Cuando lo entrevistamos poco antes de morir, recordaba el valle de Jaiña y las salitreras del Cantón de Negreiros. Quizás, desde una mirada chilena, Gamarra sería solo comparable a don Clotario Blest; por ello, en este escrito le llamaremos don Isidoro Gamarra.
El vals criollo del Pacífico. Apuntes para el estudio de la integración musical entre el Perú y Chile
Authors: Ronceros Espinoza Eligio
Published: April 2023

Es un lugar común para muchos historiadores de Perú y Chile el escribir o historiar sobre aquello que ha dividido a nuestros pueblos. Por lo cual, es todo un reto y una gran aventura escribir sobre aquello que nos une y nos ha unido en el presente y pasado. Ahora bien, si lo que se escribe e investiga es la historia de la cultura popular de nuestros pueblos, y los sentimientos y sabores presentes en la vida cotidiana del chileno y peruano promedio, lo investigado cobra especial relevancia.
Fiestas religiosas e identidades nacionales : la peruanidad ritualizada en el desierto chileno (siglo XX)
Authors: Díaz Araya Alberto
Published: April 2023

La Guerra del Pacífico es el punto de inflexión de la historia de la sociedad regional del actual norte chileno junto con los posteriores tratados internacionales que han matizado, con fricciones diplomáticas de por medio, el pulso de las identidades nacionales entre las gentes del desierto.
Conflictos entre el cetro y la espada : las misiones protestantes en las regiones de frontera entre Perú y Chile (1868-1929)
Authors: Mansilla Miguel Ángel
Published: April 2023

En este breve artículo procuraremos plantear algunas ideas y datos para proponer líneas de investigación que ayuden a superar esas carencias.
Un drama en tres actos. La lucha por el reconocimiento público de acuerdo con Dewey y Hegel
Authors: Särkelä Arvi
Published: April 2023

En lo que sigue, voy a defender la tesis según la cual John Dewey puede ser considerado como un representante de este exigente proyecto hegeliano, el cual se caracteriza por pretender dar cuenta de estos problemas centrales partiendo de una teoría del reconocimiento. Al mismo tiempo, pretendo señalar cómo y en qué medida Dewey va más allá de la versión hegeliana de este proyecto y, con ello, mostrar la plausibilidad de los rasgos fundamentales de su aproximación para la discusión actual sobre las luchas por el reconocimiento.
Adorno, Kant y la crítica al sujeto moral
Authors: Robles Gustavo
Published: April 2023

El objetivo de este trabajo es, entonces, analizar esta dialéctica de la moral kantiana que Adorno denuncia, mostrando, por un lado, su crítica a la fundamentación estrechamente racionalista de la libertad subjetiva, así como el carácter materialista-naturalista que esta crítica reivindica para repensar un concepto de libertad posidealista. Con este fin, me voy a remitir al concepto de impulsos que aparece en algunos pasajes de la obra adorniana y con el cual intenta pensar una dimensión fronteriza entre lo racional y lo somático como lugar de formas de subjetivación no represivas.
La música y los jóvenes de hoy : los hijos de la chicha
Authors: Hurtado Suárez Wilfredo
Published: April 2023

Este trabajo busca explorar las nuevas inclinaciones y gustos, así como la ubicación sociomusical y sociocultural de los jóvenes de origen andino de los sectores populares de Lima Metropolitana. En los últimos años, como producto de la mixtura y de la inserción de los migrantes en la ciudad, se produce una incorporación de nuevas opciones musicales. ¿En qué medida la música de los jóvenes se da en continuidad y ruptura respecto a las generaciones anteriores? ¿Se redefine su identificación musical? ¿Cuáles son sus preferencias?
La juventud en la otra ribera
Authors: Ribeyro Julio Ramón
Published: April 2023

El elenco se inicia con Julio Ramón Ribeyro, es decir, con una voz que fue signo preclaro de la llamada generación del 50.
Cumpleaños
Authors: Oviedo José Miguel
Published: April 2023

En esta generación de notables narradores se dieron a conocer Julio Ramón Ribeyro y Luis Loayza. Pero también otros alumnos de la PUCP de finales de esta década, como José Miguel Oviedo, Gastón Fernández y Luis Enrique Tord, ofrecerían años después su oficio de narradores.
Pánico en la clínica de tartamudos
Authors: Ampuero Fernando
Published: April 2023

La prosa de Fernando Ampuero asegura al lector la frecuentación de un lenguaje francamente conciliador de toda clase de comunicación: lectura para ser leída, comentada y conversada.
Desde el exilio
Authors: Sala Mariella
Published: April 2023

Los ochentas nos ofrecen temáticas y discursos diversos, que se enriquecen en su propia variedad y que serán una marca para la generación siguiente. Aquí tenemos cuentistas notables como Fernando Ampuero, Carlos Calderón Fajardo, Alonso Cueto, Mariella Sala, Guillermo Niño de Guzmán, Alejandro Sánchez Aizcorbe, Dante Castro y Pilar Dughi.
Evaluating Social Determinants of Health Variables in Advanced Analytic and Artificial Intelligence Models for Cardiovascular Disease Risk and Outcomes: A Targeted Review
Authors: Snowdon Jane L. , Scheufele Elisabeth L. , Pritts Jill , Le Phuong-Tu , Mensah George A. , Zhang Xinzhi , Dankwa-Mullan Irene
Published: April 2023

Introduction/Purpose

Predictive models incorporating relevant clinical and social features can provide meaningful insights into complex interrelated mechanisms of cardiovascular disease (CVD) risk and progression and the influence of environmental exposures on adverse outcomes. The purpose of this targeted review (2018–2019) was to examine the extent to which present-day advanced analytics, artificial intelligence, and machine learning models include relevant variables to address potential biases that inform care, treatment, resource allocation, and management of patients with CVD.

Methods

PubMed literature was searched using the prespecified inclusion and exclusion criteria to identify and critically evaluate primary studies published in English that reported on predictive models for CVD, associated risks, progression, and outcomes in the general adult population in North America. Studies were then assessed for inclusion of relevant social variables in the model construction. Two independent reviewers screened articles for eligibility. Primary and secondary independent reviewers extracted information from each full-text article for analysis. Disagreements were resolved with a third reviewer and iterative screening rounds to establish consensus. Cohen's kappa was used to determine interrater reliability.

Results

The review yielded 533 unique records where 35 met the inclusion criteria. Studies used advanced statistical and machine learning methods to predict CVD risk (10, 29%), mortality (19, 54%), survival (7, 20%), complication (10, 29%), disease progression (6, 17%), functional outcomes (4, 11%), and disposition (2, 6%). Most studies incorporated age (34, 97%), sex (34, 97%), comorbid conditions (32, 91%), and behavioral risk factor (28, 80%) variables. Race or ethnicity (23, 66%) and social variables, such as education (3, 9%) were less frequently observed.

Conclusions

Predictive models should adjust for race and social predictor variables, where relevant, to improve model accuracy and to inform more equitable interventions and decision making.
Elma (Malus domestica L.) Çeşitlerinin Ateş Yanıklığı Hastalığına Karşı Duyarlılık Düzeylerinin Araştırılması
Authors: KAYA Aydın , YEŞİLDAĞ Mesude Figen , ÇORUH İrfan
Published: April 2023

Bu çalışma, Erwinia amylovora’ya karşı 11 farklı elma (Malus domestica L.) çeşidinin duyarlılık reaksiyonlarını belirlemek amacıyla yapılmıştır. Çalışmada, 2014 ve 2015 yıllarında, Iğdır ilinden alınan hastalıklı bitki örneklerinden 79 bakteri straini izole edilmiş, bunlardan 58 tanesi yağ asit metil ester analizi ile E. amylovora olarak tanılanmıştır. Strainlerin koloni rengi, gram reaksiyon, katalaz, oksidaz, floresan pigment, levan koloni oluşumu ve 36 oC’de gelişme özellikleri belirlenmiştir. Ateş yanıklığı hastalığına karşı duyarlılık denemesinde Stark Crimson, Joremini, Williams Pride, Red Chief, Scarlet Spur, Fuji Zhen Aztec, Granny Smith, Mondial Gala, Amasya, Golden Reinders ve Pink Lady elma çeşitleri kullanılmıştır. Çeşitlerin duyarlılıkları yaprak ve sürgün inokulasyonuna bağlı olarak değerlendirilmiştir. Çeşitlerin patojene karşı gösterdikleri yaprak reaksiyonu sonucunda bir tanesinin çok duyarlı (Pink Lady), 4 tanesinin duyarlı (Jeromine, Granny Smith, Mondial Gala ve Amasya) ve 6 tanesinin orta derecede duyarlı (Stark Crimson, Williams Pride, Red Chief, Scarlet Spur, Fuji Zhen Astec ve Golden Reinders) olduğu saptanmıştır. Sürgün reaksiyonu sonucunda elde edilen çeşit duyarlılığına göre 8 çeşit (Stark Crimson, Jeromine, Williams Pride, Red Chief, Scarlet Spur, Fuji Zhen Astec, Granny Smith ve Mondial Gala) az duyarlı, 3 çeşit (Amasya, Golden Reinders ve Pink Lady) orta derecede duyarlı olarak belirlenmiştir.
Individuation in the era of social media
Authors: Gaist Byron
Published: April 2023

How has the virtual reality of social media impacted our self-image? Has increased communication and possibilities for public self-expression brought us closer to ourselves and others? This paper proposes to examine the negotiation of intersectional postmodern social identity via a brief examination of the functions of social media, in the framework of individuation and personality integration. The historical role of tradition and modernity / postmodernity / metamodernity is explored; suggestions are offered for the creative use of social media as an instrument of self-expression, and the future of individuation in the era of social media is discussed from a depth psychological perspective.
The impact of strategic planning in crisis management
Authors: ثابت د. محمود عبده , الأنصاري د. أحمد عبد الرزاق
Published: April 2023

The study aimed to know the level of application of strategic planning and crisis management and to measure the impact of strategic planning on crisis management in the Free Zone Authority - Aden. In addition to using the simple linear regression method to test the hypotheses of the study by taking a random sample of the employees of the Free Zone Authority - Aden, which amounted to 68 employees - a questionnaire was distributed to the study sample and the data was analyzed. In crisis management, represented in the discovery of early warning signs, damage containment, preparedness and prevention among workers in the Aden Free Zone Authority. The study also showed a weak positive impact of strategic planning on learning and decision-making in the Free Zone Authority - Aden.
Administrative Empowerment and Its Impact on The Creativity of Workers in The Government Hospitals Operating in Yemeni Countryside A field study in government hospitals in Al-Hujaria districts- Taiz
Authors: المعمري أ.د. عبد الملك أحمد أحمد , الحمادي بشير سلام أحمد سعيد
Published: April 2023

The study aimed to know the level of administrative empowerment with its dimensions (Delegation of Authority, Training, Effective Communication, Workers’ Motivation, and Building Work Teams) and its impact on workers’ creativity in government hospitals operating in the Yemeni countryside. For achieving the study objectives, the descriptive-analytical approach was used, and the study population consisted of all the workers in three governmental hospitals operating in the Al-Hujaria districts in Taiz Governorate: Khalifa Hospital, Al Nashma Hospital, and Alshheed Adnan Hospital, with a total number of (378) individuals. By the comprehensive survey method, the study questionnaire was distributed to the available study population (208) individuals, due to the decrease in employment because of the siege and the security conditions that Taiz is going through. (150) of them responded. Only (145) questionnaires were valid for analysis, at a rate of (70%) of the total distributed questionnaires. By analyzing the data using descriptive analysis methods and simple and multiple regression analysis using the SPSS program, the results of the study concluded that there is a positive impact of administrative empowerment on the workers’ creativity in government hospitals understudy, and also that there is a positive impact of the four administrative empowerment’s dimensions: delegation of authority, training, effective communication, and workers’ motivation on the workers’ creativity; while there was no impact of the team-building on the workers’ creativity in the government hospitals understudy, due to the variation in the workers’ awareness level of administrative empowerment practices.
THE EFFECT OF USING NEARSHORING STRATEGY ON CO2 EMISSIONS FOR SUSTAINABILITY IN GLOBAL TEXTILE SUPPLY LOGISTICS
Authors: SARIOĞLU D. Özgün
Published: April 2023

The new world order, in which company interests do not conflict with social interests, and social and environmental issues become the responsibility of companies, has revealed the concept of sustainability. In this context, according to the statements of the European Parliament, sustainability is also important for the textile sector, which is one of the most environmentally harmful sectors according to the amount of production and waste. On the other hand, the textile industry has a complex supply chain in which many distant chain members try to act together under globalization and cost constraints. This situation makes the sustainability studies of the textile sector difficult. However, businesses that create a sustainable supply chain structure and continuously improve this structure are expected to create a competitive advantage. In this study, the nearshore supplier strategy is adopted to improve environmental sustainability. Therefore, old inbound transpostation has calculated to understand reduction of CO2 emissions. Used calculation methods are placed in EN 16258. With this new sustainable idea, the textile company used %30 nearshore suppliers are called FM (Full Merchandised) at first two years. The reduction of CO2 emissons rate for inbound transportation became 669 t CO2 e at the end of 2022. The total emission reduction during the next 10-years period is 20122 tons CO2 e for transportation. It is obvious that this research will be a sustainability study that will create value in terms of the inbound supply process.
Can PhET simulate basic electronics circuits for undergraduate students?
Authors: Fuada Syifaul , Danuarteu Muhamad Dzikri , Agustin Sarah , Carmelya Anindya Afina , Fadhilah Iffah , Heong Yee Mei , Kaewpukdee Adisorn
Published: April 2023

PhET is one of the most powerful and impressive simulator innovations, widely used in the STEM-based learning process. Based on literature reviews, students are allowed to independently practice their skills and understanding of the material concept using this tool. PheT involves students in process competencies comprehensively and also provides a highly interactive virtual environment for STEM materials, including basic electronics, a sub-category of physics. This tool can also be easily accessed online at https://phet.colorado.edu/ or offline with a note that the user should download and install the application on a PC. An interesting question regarding this education tool is, "can PhET support basic electronics learning in Higher Education (HE)?" Numerous preliminary studies have not answered this question, which is associated with the technical aspect of the tool, because they only focused on the pedagogical aspect. Therefore, this research aims to fill this gap by exploring the capability of PhET in simulating basic electronic circuits that were commonly studied by students in HE, including Kirchoff Current Law (Kirchoof I), Kirchoff Voltage Law (Kirchoff II), Voltage Divider, Series/Parallel Resistors, Wheatstone Bridge, and Star – Delta Resistors. These circuits are simulated in two PhET products, namely, online (1.2.7) and offline (3.20) versions, with numerous setups used to compare their performances to the theoretical calculations. Finally, the answers were obtained clearly from the experimental results in the simulation environment.
Cold fronts responsible for intense winds in the Santos Basin, Brazilian Southeast Offshore Region
Authors:   Universidade Federal do Rio de Janeiro, Instituto de Geociências, Departamento de Meteorologia, Rio de Janeiro, 21941-916, RJ, Brazil, Magalhães da Silva Jamyle , Cerqueira Vasconcellos Fernanda ,   Universidade Federal do Rio de Janeiro, Instituto de Geociências, Departamento de Meteorologia, Rio de Janeiro, 21941-916, RJ, Brazil, Pereira Dereczynski Claudine ,   Universidade Federal do Rio de Janeiro, Instituto de Geociências, Departamento de Meteorologia, Rio de Janeiro, 21941-916, RJ, Brazil, Rehbein Amanda ,   Universidade de São Paulo, Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Departamento de Ciências Atmosféricas, São Paulo, 05508-090, SP, Brazil, Simões Reboita Michelle ,   Universidade Federal de Itajubá, Instituto de Recursos Naturais, Itajubá, 37500-903, MG, Brazil
Published: April 2023

This work aimed to identify the synoptic conditions associated with the cold fronts (CFs) passage that causes intense winds in the Santos Basin. Furthermore, the atmospheric characteristics of the CFs, which generated intense (INTW) and moderate (MODW) winds in the studied area, were identified. For this purpose, INTW and MODW composites of CFs episodes were elaborated. First, the INTW and MODW cases were selected from the 10 m wind intensity observed in the Santos buoy, belonging to the Brazilian National Buoys Program. Satellite images and synoptic surface charts were analyzed to identify the synoptic systems responsible for INTW and MODW in the Santos buoy, keeping only the cases generated by CFs. From the comparison between the composites, it was possible to observe in INTW: (i) a stronger pressure gradient over the Santos Basin, with the isobars presenting an almost meridional position near the basin, which caused the intense winds registered in the buoy; (ii) a baroclinic trough at medium and high levels reaching the Santos Basin region, located westward of the surface system; (iii) stronger 1000-500 hPa layer thickness and dew point temperature gradients over the continent, reaching the Santos Basin region, and (iv) a colder and drier air mass over southern Brazil. On a large scale, the Rossby wave tracings were analyzed, where different wavenumbers were noticed for each composite. In INTW, the wavenumber was 2, while in MODW, it was 2 and 3. Finally, the main characteristics found in the composites were observed in the case studies.
Application of vine copulas to estimate dew point temperature
Authors:   Associate Professor, Department of Water Engineering, University of Birjand, Birjand, Iran., Ramezani Yousef , Nazeri Tahroudi Mohammad ,   Ph.D. Graduate, Department of Water Engineering, University of Birjand, Birjand, Iran., Pronoos Sedighi Matina ,   M.Sc. student, Department of Water Engineering, University of Birjand, Birjand, Iran.
Published: April 2023

In this study, the accuracy of the copula-based model in the simulation of the dew point temperature in various climates of Iran was investigated, using simulations based on vine copulas such as C-, D-, and R-vine copulas. By examining the various vine copulas and their tree sequences, the best copula and best tree sequence based on AIC, BIC, and log-likelihood were selected. The results show that based on the complete similarity in our case between C-, D- and R-vine copulas, the selected best C-vine copulas fit well the dependence between the minimum and maximum air temperatures and dew point temperature. The simulation results were analyzed using root mean square error (RMSE), Nash-Sutcliffe efficiency (NSE) coefficient, and violin plots. The results show that the copula-based model has high accuracy at all stations. The min (max) RMSE is related to Kerman (Ahvaz) station with RMSE = 0.396 oC (0.617 oC). Also, the min (max) NSE is related to Ahvaz (Urmia) station with NSE = 0.925 (0.955). Also, according to the violin plot, it is possible to appreciate the acceptable certainty of the copula-based model. Due to the diversity of the tree sequences of vine copulas and the use of the rotated states of the internal vine copulas, as well as the possibility of interfering with the effective parameters in high dimensions, the simulation results are reliable and have no restrictions. This model can be used as the best model to estimate dew point temperature due to the full coverage of the range of changes in data.
Intrahepatic Cholangiocarcinoma and Acute Intermittent Porphyria: A Case Report
Authors: Guida Claudio Carmine , Nardella Maria , Fiorentino Leonardo , Latiano Tiziana , Napolitano Francesco , Ferrara Gaetano , Crisetti Annalisa , Mazzoccoli Gianluigi , Aucella Francesco , Aucella Filippo
Published: April 2023

Porphyrias are human metabolic diseases characterized by different modes of inheritance and clinical manifestations and caused by deficiency of enzymes of the heme biosynthetic pathway. The forms of porphyria are characterized by elevated levels of δ-aminolevulinic acid and porphobilinogen. Acute hepatic porphyrias are a subgroup of porphyrias characterized by the appearance of neurovisceral attacks with or without cutaneous signs. Acute hepatic porphyrias include four diseases: acute intermittent porphyria, variegate porphyria, hereditary coproporphyria, and hereditary δ-aminolevulinic acid dehydratase deficiency. These enzymatic deficiencies cause a harmful accumulation of porphyrins in the liver and bone marrow that trigger a wide range of signs and symptoms. Patients suffering from different forms of acute hepatic porphyria present a high risk of liver cancer, precisely hepatocellular carcinoma and cholangiocarcinoma, determined by the activity of the disease even though an exact mechanism of carcinogenesis has not been recognized yet. Here, we present the clinical case of a 72 year old woman who, approximately 29 years after the diagnosis of acute intermittent porphyria, presented with intrahepatic cholangiocarcinoma with histological diagnosis of adenocarcinoma starting from the biliary-pancreatic ducts, which was diagnosed during the clinical and anatomopathological evaluation of a pathological fracture of the femur.
Predicting 6000m Performance Time in Junior Rowers using a 500m Indoor Rowing Test
Authors: Silva Luiz Felipe da , Almeida-Neto Paulo Francisco de , Gama Dihogo , Miarka Bianca , Aidar Felipe J. , Silva Tais dos Santos , Sabido Victor , Neto Rui Barbosa , Slimani Maamer , Dantas Paulo Moreira Silva , Cabral Breno Guilherme de Araújo Tinoco
Published: April 2023

The present study aimed to develop a mathematical model to estimate the performance of an indoor rowing event of 6000m through an 500 m all out test in junior athletes. We selected141 subjects from the Brazilian rowing confederation database (15.9 ± 1.0 years), subsequently randomised the sample to the development (~70%) and cross-validation (~30%) groups of the mathematical model. Performance data for 500m and 6000m were collected (there was a 48h washout between one test and anoth-er).Subsequently, the mathematical model: Time(min) 6000m = { [( Time(s) 500-m * 6) * 2] / 60} + 1.3, was developed by arithmetic modeling using machine learning and Regression analysis, being tested by intraclass correlation coefficient (ICC), Concordance correlation coefficient (CCC), Validity (Cb ), preci-sion (ρ) and bland-Altman plotting. The prediction of the result of 6000m through the mathematical model utilizando apenas o desempenho de 500m “all-out” test showed a significant reliability in de-velopment group (r2 = 0.730, ICC = 0.753; CCC = 0.895, Cb = 0.879, ρ: 0.957, pure error: 0.2 secounds (1.0% estimative error)); and in cross-validation group (r2 = 0.710, ICC = 0.747; CCC = 0.888, Cb = 0.875, ρ: 0.903, pure error: 0.3 secounds (1.4% estimative error)). When comparing the estimated re-sults of the 6000m performance by the mathematical model with the real performance of 6000m per-formed in indoor rowing, no statistical differences were observed. In addition, the mathematical model did not present a significant proportion bias in relation to the 6000 m performance in both groups. The mathematical model for predicting 6000m performance through a 500m fast test was significant for national level junior rowing athletes.
Identification of Novel Biomarkers in Peripheral Blood Mononuclear Cells of Hepatocellular Carcinoma Patients
Authors: R Sindhoora
Published: April 2023

In this study, novel biomarkers in Blood Mononuclear Cells (PBMCs) of Hepatocellular Carcinoma (HCC) patients were identified through microarray data analysis. The problem that prompted the study was the lack of reliable biomarkers for early diagnosis and monitoring of HCC. The purpose of this study was to discover potential biomarkers in PBMCs of HCC patients that can be used for early diagnosis and monitoring of the disease. The main hypothesis was that there are genes that are overexpressed in PBMC of HCC patients compared to healthy individuals. The results showed that genes HBB, WBP2, HBA2, and HBA1 were overexpressed in PBMCs of HCC patients. Additionally, nine genes were found to be upregulated in HCC patients and had a relation between KEGG pathways of RA, suggesting a link between the two diseases. These genes are TLR4, IL1B, CXCL5, IL11, HLA-DQA1, HLA-DRA, LBT, ATP6V1B2 and ATP6V1C1. The Gene ontology analysis revealed biological processes used in the process of how these genes play a role in development of HCC. In conclusion, this study identified potential biomarkers in PBMC of HCC patients that can aid in early diagnosis and monitoring of the disease. The findings of this study have important implications for improving the clinical management of HCC patients.
Evolutionary Multi-Objective Optimization of Extrusion Barrier Screws: Data Mining and Decision Making
Authors: Gaspar-Cunha António , Costa Paulo , Delbem Alexandre Cláudio Botazzo , Monaco Francisco , Ferreira M. J. , Covas José A.
Published: April 2023

: Polymer single screw extrusion is a major industrial processing technique used to obtain plastics products. To assure high outputs, tight dimensional tolerances, and excellent product performance, extruder screws may show different design characteristics. Barrier screws, which contain a second flight in the compression zone, have become quite popular as they promote and stabilize polymer melting. Therefore, it is important to design efficiently extruder screws and decide whether a conventional screw will do the job efficiently, or a barrier-screw should be considered instead. This work uses multi-objective evolutionary algorithms to design conventional and barrier screws (Maillefer screws will be studied) with optimized geometry. Processing of two polymers, Low Density Polyethylene and Polypropylene, is analyzed. A methodology based on the use of Artificial Intelligence (AI) techniques, namely data mining, decision making and evolutionary algorithms, is presented and utilized to obtain results with practical significance, based on relevant performance measures (objectives) used in the optimization. For the various case studies selected, Maillefer screws were generally advantageous for processing LDPE, while for PP the use of both types of screws would be feasible.
MWaste: A Deep Learning Approach to Manage Household Waste
Authors: Kunwar Suman
Published: April 2023

Computer vision methods have shown to be effective in classifying garbage into recycling categories for waste processing, existing methods are costly, imprecise, and unclear. To tackle this issue, we introduce MWaste, a mobile application that uses computer vision and deep learning techniques to classify waste materials as trash, plastic, paper, metal, glass or cardboard. Its effectiveness was tested on various neural network architectures and real world images, achieving an average precision of 92% on the test set. This app can help combat climate change by enabling efficient waste processing and reducing the generation of greenhouse gases caused by incorrect waste disposal.
Pengaruh Kompensasi dan Lingkungan Kerja terhadap Kepuasan Kerja pada Karyawan Persekutuan Komanditer di Bogor
Authors: Ardi Nugroho Yusuf , Wahyu Handaru Agung , Wiradendi Wolor Christian
Published: April 2023

The purpose of this study is to determine whether compensation and work environment have an influence on job satisfaction for employees of CV Mutiara Jaya Berkah. This study used a sample of 62 employees of CV Mutiara Jaya Berkah. This study used a quantitative approach with descriptive and explanatory analysis methods. Data was collected by distributing survey questionnaires to 62 employees of CV Mutiara Jaya Berkah. The data analysis method used in testing the hypothesis in this study is the SEM (Structural Equation Model) method. The results of this study indicate that compensation and the work environment have a positive and significant effect on employee’s job satisfaction at CV Mutiara Jaya Berkah.

Keyword: Compensation, Work Environment, Job Satisfaction

 

Tujuan dari penelitian ini yaitu untuk mengetahui apakah kompensasi dan lingkungan kerja memiliki pengaruh terhadap kepuasan kerja pada karyawan CV Mutiara Jaya Berkah. Penelitian ini menggunakan sampel sebanyak 62 orang karyawan CV Mutiara Jaya Berkah. Penelitian ini menggunakan pendekatan kuantitatif dengan metode analisis deskriptif dan eksplanatori. Pengumpulan data dilakukan dengan menyebarkan kuisioner survei kepada 62 orang karyawan CV Mutiara Jaya Berkah. Metode analisis data yang digunakan dalam pengujian hipotesis pada penelitian ini yaitu dengan Metode SEM (Model Persamaan Struktural). Hasil dari penelitian ini menunjukkan bahwa kompensasi dan lingkungan kerja memiliki pengaruh positif dan signifikan terhadap kepuasan kerja karyawan CV Mutiara Jaya Berkah.
Pengaruh Perputaran Modal Kerja, Likuiditas, dan Solvabilitas Terhadap Kinerja Perusahaan Sektor Manufaktur yang Terdaftar di Bursa Efek Indonesia Periode 2014 – 2018
Authors: Roswanti Pratami Dara , Mardiyati Umi , Dharmawan Buchdadi Agung
Published: April 2023

The purpose of this study is to determine the effect of working capital turnover, liquidity, and solvency on the performance of manufacturing sector firms listed in Indonesia Stock Exchange period of 2014-2018. The variables used in this study are working capital turnover, amihud illiquidity, and Debt to Asset Ratio (DAR) as independent variables, company performance (proxied by ROA and Tobin's Q) as the dependent variable. The sample used in this study consist of 103 companies. The sampling method used was the purposive sampling method, with the balanced panel data as a data analysis method. The results of this study indicate that working capital turnover and amihud illiquidity has no significant effect on the company's performance, while Debt to Asset Ratio (DAR) has a significant negative effect on company performance (on ROA proxy) and significant positive effect on company performance (on Tobin's Q proxy).

 

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perputaran modal kerja, likuiditas, dan solvabilitas terhadap kinerja perusahaan sektor manufaktur yang terdaftar di Bursa Efek Indonesia periode 2014-2018. Variabel yang digunakan dalam penelitian ini adalah perputaran modal kerja, likuiditas amihud, dan Debt to Asset Ratio (DAR) sebagai variabel bebas, kinerja perusahaan (diproksikan dengan ROA dan Tobin's Q) sebagai variabel terikat. Sampel yang digunakan dalam penelitian ini berjumlah 103 perusahaan. Metode pengambilan sampel yang digunakan adalah metode purposive sampling, dengan metode analisis data balanced panel data. Hasil penelitian ini menunjukkan bahwa perputaran modal kerja dan likuiditas amihud tidak berpengaruh signifikan terhadap kinerja perusahaan, sedangkan Debt to Asset Ratio (DAR) berpengaruh negatif signifikan terhadap kinerja perusahaan (pada proksi ROA) dan berpengaruh positif signifikan terhadap kinerja perusahaan (pada proksi Tobin's Q).
Data-centric artificial olfactory system based on the eigengraph
Authors: Sung Seung-Hyun , Suh Jun Min , Jang Ho Won , Park Jeon Gue , Jun Seong Chan
Published: April 2023

Recently reported studies of electronic nose systems that combine chemiresistive gas sensors with computational analysis technologies tend to waste significant amount of important data. Since the sensitivity-oriented data composition have made it difficult to discover meaningful and valuable data to apply artificial intelligence analysis in terms of in-depth analysis of odor attributes specifying the gas identities, ultimately resulting in hindering the development of artificial olfactory technology. Here, we propose a novel data-centric approach for realizing a standardized artificial olfactory system inspired by the human olfactory mechanism. We designed an olfactory receptor-like sensor array in which each channel has independent gas sensing characteristics through semiconductor processes. In addition, the physicochemically optimized sensor array reproducibly generated eigengraphs with highly refined waveforms which contribute keeping invariability of input space to deep learning architecture. The implicit odor attributes of the time domain eigengraphs were mathematically represented by the newly defined frequency domain feature vectors. The effectiveness of the MFCC feature vectors in deep learning for gas classification was clearly demonstrated in terms of training time reduction and inference performance improvement despite the extremely decreased amount of training data. We suggest that our strategy can be widely applied as a source technology to develop standard artificial olfactory systems.
Knowledge and Attitude on Preconception Care and Associated Factors Among Women of Reproductive Age With Chronic Disease Who Have Follow-up at Amhara Regional State Referral Hospitals, Ethiopia, 2022; Multicenter Cross-sectional Study
Authors: Demeke Muluken , Yetwale Fisseha , Mulaw Zerfu , Yehualashet Daniel , Gashaw Anteneh , Agegn Berihun
Published: April 2023

Introduction: Preconception care is an important window to target maternal morbidity and mortality, especially for women who have chronic diseases. However, little was known about knowledge and attitudes towards preconception care among women of reproductive age with chronic disease. Therefore this study aimed to assess Knowledge and attitude on preconception care and associated factors among women of reproductive age with chronic disease who have follow-up at Amhara Regional State Referral Hospitals, Ethiopia, 2022.
Method:A multicenter cross-sectional study design was conducted among 828 women of reproductive age from April 15 to June 1, 2022. A multistage sampling technique was employed to select study participants. Data was collected by using a structured interviewer-administered questionnaire and chart review. Bi-variate and multivariable logistic regression analyses were carried out, and statistical significance was declared with P <0.05 and AOR with a 95% confidence interval.
Result:This study found that 55.6% of respondents had a good knowledge on preconception care, and about half of the women (50.2%) had a good attitude towards PCC. Women, who attended formal education (AOR: 1.997, 95% CI: 1.247, 3.196), prim-parity (AOR: 2.589, 95% CI: 1.132, 5.921), received preconception counseling (AOR: 3.404, 95% CI: 2.170, 5.340), duration of disease ≥ 5 years (AOR: 6.495, 95% CI: 4.091, 10.310) were significantly associated with knowledge on PCC. Woman's age ≥35years (AOR: 2.143, 95% CI: 1.058, 4.339), women who attended secondary education and above (AOR: 2.427, 95% CI: 1.421, 4.146), history of modern family planning use (AOR: 2.853 95% CI: 1.866, 4.362), received preconception counseling (AOR: 2.209, 95% CI: 1.429, 3.414) and having good knowledge on PCC (AOR: 20.629, 95% CI: 12.425, 34.249) were significantly associated with attitude towards PCC.
Conclusions:The finding of this study showed that women’s knowledge and attitude on preconception care were relatively low. Health professionals in the study area shall counsel women to improve knowledge and attitude on preconception care.
Deep and Transfer Learning based methods for Left Ventricle segmentation from cardiac MRI images to identify cardiovascular ailments
Authors: Bhan Anupama , Mangipudi Parthasarathi , Goyal Ayush
Published: April 2023

In order to diagnose cardiovascular disease (CVD) in its early stages, the position of the Left Ventricle (LV) and relevant parameters associated with it plays significant role in the medical field. The timely diagnosis of CVDs works as a lifesaver in many cases. In the earlier days, the position and functioning of the LV was assessed by the error-prone manual methods. Nowadays, the newer and smart technologies have allowed the medical practitioners to make use of auto-segmentation methods for diagnosis of heart problems in early stages. It is difficult to assess the functioning of the LV due to some listed reasons a) a bigger span and changing the size of LV in MRI scanning , b) Varied myocardial and blood-pool fragments, c) Similarity in shape between the LV and other body organs and d) Noise in images. Hence assessing the LV for the accurate identification of echocardiographic parameters still remains the challenge for diagnosing CVDs. Many researchers deploy methods based on Machine learning (ML) and deep learning (DL) to get accurate results for LV segmentation (LVS0. It helps in segmenting the LV and revealing the clearer parts of the image for better classification and diagnosis. In this research study, three methods are deployed for the segmentation of LV images namely CNN based U-Net Model , VGG 16 and ResNet 152. These methods have been implemented for the segmentation of the images obtained from MRI scan to explore the position of left ventricle and problems in LV which leads to other lethal heart ailments. These approaches help in the identification of cardiac parameters related to CVDs. The proposed algorithms are compared using standard performance metrics to assess the output and viability of the projected techniques as discussed in the result section of this article. The Blockchain database has been considered as the source of input images and this research is applicable universally due to its nature of considering latest technologies to identify CVDs. The results of DL algorithms (DLA) reveal that the CNN-based U-Net Model outperforms the other two methods (VGG 16 and ResNet 152) for accurate identification of CVDs from the LV segmentation techniques.
Mechanisms of BMPR2 in the Development and Progression of Osteoporosis: An Experimental Study in Mice
Authors: Yingzhu Qiu , Yao Sun , Kun Sun
Published: April 2023

Introduction: Osteoporosis is a bone disease characterized by reduced bone mass, disrupted microarchitecture, and deteriorated bone strength, leading to increased fracture risk. The dysfunction of bone cells is associated with various factors, making it important to study the regulatory mechanisms of bone cells for prevention and treatment of osteoporosis. BMPR2 is a critical molecule in the BMP signaling pathway, regulating osteoblast proliferation, differentiation, and bone formation processes. Decreased BMPR2 expression is associated with osteoporosis, but its specific mechanisms are unclear.
Materials and Methods: Twelve-week-old C57BL/6 mice were divided into experimental and control groups, with 10 mice in each group. The experimental group was injected with BMPR2 siRNA into the left tibia, while the control group was injected with PBS. Osteoblasts were isolated and cultured, and their proliferation and differentiation were detected using MTT assay and ALP staining. The experimental data were statistically analyzed using SPSS 20.0 software.
Results: BMPR2 siRNA significantly reduced osteoblast proliferation (P<0.05) and differentiation (P<0.01). The bone density of the experimental group of mice was significantly decreased (P<0.01).
Conclusion: BMPR2 plays an important role in the development and progression of osteoporosis, regulating osteoblast proliferation, differentiation, and bone formation processes. Targeting BMPR2 may provide new therapeutic strategies for the prevention and treatment of osteoporosis.
Multiple factors causing alignment instability in childhood concomitant strabismus
Authors: Guo Yanan , Guan Yuehan , Li Li , Jiang Jingjing
Published: April 2023

Purpose:To investigate the potential factors related to alignment instability in childhood concomitant strabismus.
Design: Prospective cohort study.
Methods: In total, 198 children with concomitant strabismus (57 esotropia, 141 exotropia) underwent repeat prism and alternate cover tests (PACTs) by two orthoptists who were certified by the study, and sensory tests were all performed once. We defined the alignment measurement as stable if the absolute value of the measurement difference between two orthoptists was within 10 prism diopters (PD) at distance or at near, and unstable if the difference was 10 PD or greater at distance or at near. We analyzed the relationship between the measurement variability and sensory results, patient age, and angle of deviations.
Results: The mean age of the esotropia and exotropia patients was 68.5 ± 26.3 months (range, 36–164 months) and 96.1 ± 33.6 months (range, 22–200 months), respectively, and there was a significant difference in suppression related alignment instability, both at distance (P= 0.005) and at near (P = 0.039). Anisometropia also showed a significant difference at distance (P = 0.033) for alignment instability, and there was no significant statistical effect of age on measurement variability in our study. Alignment instability is positively associated with the angle of deviation, especially at distance (P = 0.019 for exotropia, P= 0.002 for esotropia).
Conclusion: Clinical characteristics are proven related to alignment instability, and suppression is an important factor for alignment instability in childhood concomitant strabismus. Nevertheless, it would be entirely reasonable to consider alignment instability in relation to other factors, such as anisometropia and a large angle of strabismus, when evaluating patient deviations.
Trial registration: Chinese Clinical Trial Registry, ChiCTR2200062404, Registered 4 August 2022.
Boosting Question Answering Systems with Multi-Label Classification Techniques
Authors: Chen YiHui , Lu Eric Jui-Lin , Jin-De
Published: April 2023

DBpedia is one of the most resourceful link databases today, and to access information in DBpedia databases, we need to use query syntax (e.g., SPARQL). However, not all users know SPARQL, so we must use a natural language query system to translate the user's query into the corresponding query syntax. It is costly and time-consuming for the query system to generate query syntax. Therefore, this paper proposes generating query syntax from natural language. Two multi-label learning methods are used for question transformation: Binary Relevance (BR) and Classifier Chains (CC). To predict all the labels that match the query intentions, we use Recurrent Neural Networks (RNNs) to build a multi-label classifier for generating RDF triples. To better consider the relationship between RDF triples, the Binary Relevance is integrated into an ensemble learning approach to propose an Ensemble BR. The experiments perform better than the other research to improve the query accuracy.
Persistent Pain following Total Knee Arthroplasty; The Role of Underlying Diseases
Authors: Teimouri Mehdi , Motififard Mehdi , Shahsavan Mohammad
Published: April 2023

The authors have requested that this preprint be removed from Research Square.