bluuebunny/crossref_metadata_2025 huggingface dataset:
Disaharidase deficiency – is one of the causes of functional disorders of intestine.
Authors: Parfenov Asfold I. , Ahmadullina O. V. , Belostoskij N. I. , Sabelnikova E. A. , Bykova S. V. , Khomeriki S. G. , Kirova M. V.
Published: November 2020

The aim of the study was to show the importance of intestinal carbohydrase (glucoamylase, maltase, sucrase and lactase) in the etiology and pathogenesis of functional bowel diseases. Material and methods. It was examined 74 patients with FBD in age from 18 to 50 years (36 men and 38 women.). According to Rome IV criteria (2016) 21 had irritable bowel syndrome (IBS) with predominance of diarrhea , 33 functional diarrhea, 6 - IBS with predominant constipation , 4 functional constipation and 10 IBS mixed type. Karbohidrase activity in mucosa of the small intestine was investigated by the method of Dahlquist modification Trinder in duodenal biopsies obtained during esophagogastroduodenoscopy. Results. Lactase deficiency identified in 87.8%, maltasa - 48.6 percent, saharasia - 51,3%, the lack of glucoamylase - in 85.1% of patients. The activity of all investigated enzymes was reduced in 23 (31.1%) patients with functional bowel disease. Normal activity of enzymes have 4 (5,4%) patients. Conclusion. In 70 of 74 patients with functional bowel disease violations of the chair, abdominal pain and flatulence due to the decrease in the activity of carbohydrase of mucosa. The reason of disaccharidase deficiency may be due to the acute intestinal infections, antibiotic and medicine (NSAIDs) treatment.
Tuberculosis of the larynx in a
patient with long­term current laryngitis.
Authors: Kirasirova E. A. , Piminidi O. K. , Lafutkina N. V. , Mamedov R. F. , Rezakov R. A. , Sotnikova T. N.
Published: November 2020

This case report demonstrates a case of isolated tuberculosis of the larynx in a patient with a prolonged inflammatory process of the larynx with a suspected malignant tumor and led to stenosis of the respiratory tract. The report is interest as an example of long-term (3 years) diagnostic search and the complexity of differential diagnosis of the disease.
Cardiovascular risk in rheumatoid arthritis.
Authors: Omelchenko V. O. , Korolev M. A. , Pospelova T. I. , Konenkov V. I.
Published: November 2020

The problem of high mortality in patients with rheumatoid arthritis, one of the most common autoimmune diseases, is still unsolved. Many studies have shown a significant impact on cardiovascular risk of both traditional and non-traditional risk factors (genetic, RA-associated etc). To improve the individual prognosis, team actions by physicians of different specialties are necessary on the basis of good awareness and patients ’ compliance. The aim of the review was to characterize the main factors involved in the formation of cardiovascular risk and give a notion about the features of its assessing in patients with rheumatoid arthritis. Literature search was carried out using Scopus, Web of Science, RSCI by keywords.
Quality of care for patients with myocardial infarction with ST segment elevation. real clinical practice of the invasive center.
Authors: Ryabov V. V. , Demianov S. K. , Syrkina A. G. , Belokopitova N. V. , Vyshlov E. V. , Maximov I. V. , Baev A. E. , Markov V. A. , Karpov R. S.
Published: November 2020

According to the Russian registry RECORD, the hospital mortality at STEMI in domestic hospitals remains high, which is due to the low frequency of reperfusion measures. There are problems in treatment patients of senile age. Comparative studies of the quality of care for patients with acute coronary syndrome were not conducted in Russia. 489 patients with STEMI, arrived in the first 24 hours from the onset of MI were analyzed. Quality of care for patients with STEMI was evaluated according to the quality criteria of the Association of Emergency Cardiovascular Care of the European Society of Cardiology. To compare the quality of care for patients of different age groups, the endpoints were the frequency of use of TLT and primary PCI, the incidence of cardiogenic shock, pulmonary edema, acute left ventricular aneurysm, and acute psychotic disorders. It is shown that patients with STEMI receive emergency medical care of high quality in adequate time. Elderly STEMI patients are less likely to undergo percutaneous coronary intervention, have more extensive myocardial damage with severe left ventricular failure and acute psychotic disorders, which is associated with a multiple increase in hospital mortality. The most frequent reasons for rejecting PCI were acute mental disorders, multivessel diffuse lesions of the coronary arteries with pronounced calcinosis, small diameter of the artery. It is necessary to develop new devices or techniques for PCI in conditions of severe multivessel lesions of coronary arteries with pronounced calcification, and also develop methods of neuroprotection in order to overcome existing barriers in providing emergency high-tech medical care to elderly STEMI patients.
Lipid­carbohydrate metabolism and nutrition in the indigenous and non­indigenous population of the north-east of Russia.
Authors: Averyanova I. V. , Maksimov A. L.
Published: November 2020

Scientific-research center «Arktika» far-eastern branch of the Russian academy of sciences, 685000, Magadan, Russia Young male residents ofMagadan region and Chukotsky Autonomous District aged 17-21, all are representatives of Russia’s northeast ethnic peoples were examined in comparison with Caucasoid subjects born in the north in the p>-2 generation to study the blood lipid and glucose values as well as the dietary structure. In order to ascertain the subjects ’ lipid and carbohydrate basic values, the CardioChek PA biochemical express-analyzer (USA) was used during the study of the capillary blood samples taken from the examinees on empty stomach, 10-12 hours after the last meal. Besides, the program set of “ASPON-nutrition” was used to analyze the subjects ’ daily diets for assessing their dietary structures and nutrition facts. All the examined subjects demonstrated the similar changes in lipid-carbohydrate profile resulted in low fat metabolism and high glucose close to the upper limit of physiological norm. Reliable ethnic and region-related peculiarities in the studied metabolic parameters were found. Of note, that Aboriginal subjects were the highest in the blood glucose. They showed higher values ofLPHD and lower values ofLPLD compared to those of Caucasoid subjects. Significant nutrition irrationalities such as imbalance in macronutrients and energetic deficiency were found. The observed diets contain excess carbohydrates and insufficient protein and fat saturation at lowered daily energetic value for the given age cohort.
Multiple symmetrical lipomatosis (Madelung’s disease) in the clinic of internal diseases.
Authors: Esedov E. M. , Abasova A. S. , Musaeva L. N. , Magomedeminova S. R.
Published: November 2020

Clinical and experimental research is mainly devoted to the general obesity as a systemic disease. In clinical practice constitutional secrete exogenous (primary) and secondary types of Obesity. The peculiarities of distribution are distinguished abdominal (android), glyuteo-femoral (gynoid) obesity options regardless of the reason for its development. For the clinic is important to the study of obesity as a systemic disease because it causes the development of diseases of the cardiovascular system (coronary heart disease, hypertension), metabolic syndrome, liver disease, kidney and other organs. Preventive, diagnostic and therapeutic measures are aimed at preventing or reducing the clinical manifestations of obesity in order to preserve the health and quality of life ofpatients. However, the pathology of adipose tissue is also seen limited (focal) deposition of fat (especially subcutaneous) in different parts of the subcutaneous fat.
Monoclonal gammopathy in patient with gastric adenocarcinoma.
Authors: Yagoda A. V. , Gladkih N. N. , Aydemirov A. N. , Yagoda S. A.
Published: November 2020

In the presented case the patient with highly differentiated gastric adenocarcinoma developed a rare paraneoplastic syndrome with paraproteinemia, that resulted in hemorrhagic syndrome, severe anemia, hypercoagulation and complications of compatibility tests during blood transfusion.
Respiratory muscle dysfunction and chronic obstructive pulmonary disease.
Authors: Geltser B. I. , Kurpatov I. G. , Kotelnikov V. N.
Published: November 2020

The review presents literature data on the problem of respiratory muscle (RM) dysfunction in patients with chronic obstructive pulmonary disease (COPD). In the development of RM dysfunction, both local and systemic factors of the pathogenesis of COPD are important. Local factors are associated with lung remodelling and the need to overcome RM excessive breathing resistance, which increases the intensity of their work, contributes to the development of hypertrophy and insufficiency. Chronic systemic inflammation, oxidative stress, excessive proteolysis and other systemic manifestations of COPD change the metabolism and structural and functional organisation of RM. Low nutritional status, increasing protein-energy deficiency, electrolyte imbalance, endocrine disorders against the background of progressive respiratory insufficiency and tissue hypoxia contribute to the development of RM weakness. The combination of COPD, acute disorders of cerebral circulation and chronic heart failure sharply worsens the function of RM and the prognosis of comorbid diseases. Also, the dysfunction of RM in patients with COPD is significantly aggravated at the age of senility. The review discusses the possibilities of pharmacological correction of RM dysfunction and other clinical aspects of this problem.
Indicators of cognitive functions in patients after coronary artery bypass grafting (five-year follow-up).
Authors: Maleva O. V. , Artamonova A. I. , Syrova I. D. , Trubnikova O. A. , Barbarash O. L.
Published: November 2020

Purpose. We aimed to evaluate the long-term results of cognitive functions in patients in 1 year and 5 years after coronary artery bypass grafting (CABG). Material and methods. We examined 98 men aged 45-69years. Cognitive functions were evaluated prior to CABG, 1 year and 5 years after CABG. Discussion. The evaluation of neuropsychological status allowed to diagnose a cognitive decline and to compare the dynamics at different stages of the study: baseline 1 year and 5 years later in patients after CABG. Various dynamics in the basic cognitive domains (upon the indicators of memory, attention and neurodynamics) was revealed in the long-term postoperative period. The positive dynamics in the tests for attention and memory in the annual stage is probably provided by the “learning effect ” and relative “simplicity ” of the tasks execution. The regression of memory and attention indicators by the fifth year of the study till the baseline preoperative level was probably the result of the combination offactors: a natural age decline in cognitive functions, a large gap between the studies (4 years) and of course a long-term CABG effect. The studied sample of the patients was interested in convalescence, highly motivated and compliant to medical recommendations at all the stages of postoperative period. Results. Multidirectional dynamics in cognitive indicators was noted at annual and five-year stages offollow-up in patients underwent CABG. By the first year after CABG there was a significant tendency towards the improvement of cognitive functions in memory, attention and neurodynamics indicators. At the five-years follow-up stage there was a regression in memory, attention and neurodynamics indicators towards the baseline preoperative level. Conclusions. The active curation of patients after CABG by a multidisciplinary team will allow to timely reveal a cognitive
Management of cardiovascular risk at patients with a diabetes mellitus type 2.
Authors: Pashentseva A. V. , Verbovoy A. F. , Galkin R. A. , Verbovaya N. I. , Sharonova L. A. , Dolgikh Yu. A.
Published: November 2020

Diabetes mellitus represents a serious medico-social problem that is caused by its high prevalence, a tendency to body height of number ofpatients, a high invalidism and a mortality. The main reason for death ofpatients with a diabetes mellitus type 2 is the pathology of cardiovascular system bound to an atherosclerosis to which leads lack of adequate compensation of a disease. In this article various risk factors of cardiovascular pathology at patients with a diabetes mellitus are surveyed and modern opportunities in their correction are discussed.
Pathogenetic aspects of bone metabolism in diabetes mellitus.
Authors: Safarova S. S.
Published: November 2020

Metabolic disorders caused by diabetes affect bone remodeling, alter the structure and reduce the strength of bone tissue, leading to the development of diabetic osteopathy. However, between diabetes mellitus (DM) type 1 and 2 there are noticeable differences in the effect on the bone structure, which is obviously due to the different cellular and molecular mechanisms of these processes. The density of bone tissue with DM typel decreases, which leads to an increase in the risk of fractures by 7 times. With DM type 2, bone mineral density is moderately elevated, which is expected to lead to a decrease in the incidence of osteoporotic fractures, but in fact, this index is approximately doubled. Pathophysiological mechanisms underlying osteoporotic changes in diabetes mellitus are complex and included hyperglycemia, oxidative stress and accumulation of advanced glycation endproducts that alter the properties of collagen, increase fatty infiltration of the bone marrow, release inflammatory factors and adipokines from visceral adipose tissue and potentially change the function osteoblasts. Additional factors are, some antidiabetic drugs that directly affect the metabolism of bones and minerals (such as thiazolidinediones), as well as an increased tendency to fall due to micro- and macroangiopathies, all contribute to an increased risk of low-fracture fractures in patients with diabetes mellitus.
Influence of microcirculatory disorders in patients with moderate
chronic obstructive pulmonary disease and systemic arterial hypertension on acid-base and gas balance of blood.
Authors: Zarubina E. G. , Shaldybina Y. E. , Prokhorenko I. O.
Published: November 2020

Material and methods. The clinical study involved 240patients (228 men and 12 women) aged 40 to 55, they were divided into 3 groups based on the duration of the disease. Patients of the first group suffered COPD disease up to 5 years, in the second group it was up to 10 years and in the third group it was more than 10 years. The degree of disturbance of microcirculation processes was investigated using laser Doppler flowmetry at the multifunction laser diagnostic complex “LAKK-M” (Russia, 2011). The following parameters were evaluated: the average perfusion value, saturation of mixed (capillary) blood, saturation of arterial blood, relative volume of the erythrocyte fraction in the skin of the middle fingertip, the index ofperfusion oxygen saturation in the microcirculation, the index of specific oxygen consumption in the tissue. The following parameters were also calculated: the efficiency of oxygen exchange, the fluorescence indicator of oxygen consumption; analysis of the frequency spectrum in the zone of myogenic, neurogenic and respiratory fluctuations of the blood flow. Results. As part of the study it was found that the increase in the prevalence of hypertension is increased in patients with COPD, depending on the duration of the disease: 2.5 times in patients of the 2nd group and 3.7 times in patients of the 3rd group compared with the patients of the 1st group. Based on the analysis of laser Doppler flowmetry data, the microcirculation index significantly changes in patients with COPD and AH in comparison with patients with isolated COPD by 5.7% (p <0.05) in the 1st group, by 11.8% (p <0.01) and 23.5% (p<0.001) in 2 and 3rd groups, respectively. Conclusion. The role of microcirculatory disorders was established in patients with comorbid pathology in the development of disorders in the gas composition parameters and acid-base balance of blood in patients with chronic obstructive pulmonary disease and systemic arterial hypertension, as well as the relationship between the duration of the anamnesis of comorbid pathology and the severity of the revealed disorders.
Variability of glycemia and cognitive impairment in patients with diabetes mellitus type 1.
Authors: Samoylova Yu. G. , Matveeva M. V. , Zhukova N. G. , Rokank M. A.
Published: November 2020

Diabetes mellitus type 1 is associated with impaired cognitive function. Based on the results of systematic reviews and meta-analyzes, the most likely modifiable risk factor is the degree of metabolic control, in particular the variability of glycemia. Aims: to determine the influence of the variability of glycemia on cognitive functions in patients with type 1 diabetes mellitus. Material and methods. Design-observational, one-stage, cross-sectional research. We examined 30 patients with type 1 diabetes mellitus who were divided into 2 groups: 1 group (main) with cognitive impairment, and 2 (control) with normal cognitive functions. All patients were screened for cognitive functions using the Montreal scale (MoCa test). For the diagnosis of fluctuations in glucose level, continuous monitoring of glycemia was carried out using the iPro-2 device (Medtronic, USA): mean glycemic mean (MEAN), standard deviation (SD), mean amplitude of glycemic fluctuation (MAGE), long-term glycemic index (CONGA) Glycemia lability index (LI), hypoglycemia risk index (LBGI), hyperglycemia risk index (HBGI), mean hourly rate of glycemic change (MAG). Results. The study revealed that in patients with type 1 diabetes mellitus, cognitive impairment was dominated by a violation of constructive praxis, memory and attention. Recorded a significant difference in MEAN, SD, CONGA, Gindex, LBGI, HBGI, MAGE, Mvalue and MAG. Correlation analysis revealed the relationship of cognitive impairments with the level of HbA1c, as well as the variability parameters MEAN, SD, CONGA, Gindex, LBGI, HBGI, MAGE, Mvalue, MAG. Conclusions. The relationship between the variability of glycemia and cognitive impairment was registered in patients with type 1 diabetes mellitus
Diagnostic possibilities of echocardiography using the technique of speckle tracking imaging in ischemic heart disease
Authors: Babkina T. M. , Smyrnova Anna S.
Published: November 2020

Speckle tracking echocardiography is a recently developed technique for the characterization and quantification of myocardial deformation. By allowing measurement of the different components of myocardial deformation, it provides information about its physiology of contraction and relaxation. Among all the strain parameters, longitudinal strain is more reproducible than the radial and circumferential strain and rotation. The analysis of numerous sources of scientific literature dedicated to the diagnostic possibilities of this technique for ischemic heart disease is reflected in our work.
Modes of antiviral therapy containing daclatasvir, when mixed cryoglobulinemia associated with chronic infection with
hepatitis C virus (multicentre study in the framework of individual access)
Authors: Ivashkin V. T. , Abdurakhmanov D. T. , Bakulin I. G. , Zubkin Mikhail L. , Kizhlo S. N. , Mayevskaya M. B. , Sagalova O. I. , Kim I. G. , Chervinko V. I.
Published: November 2020

Mixed cryoglobulinemia (MC) and cryoglobulinemic vasculitis (CV) are the most frequent extrahepatic manifestations in chronically infected hepatitis C virus (HCV) patients. Antiviral therapy with interferon and ribavirin used to play an important role in the complex of therapeutic measures in patients with CV. Modern direct-acting antiviral (DAA) drugs radically improved the results of treatment of uncomplicated chronic hepatitis C. This study evaluated the efficacy and safety of daclatasvircontaining regimens of antiviral therapy in asymptomatic MC and CV associated with chronic HCV infection. The study included 25 HCV-infected patients with MC at the age of 53.9 ± 11.6 years. The genotype of virus 1b was determined in 21 (84%) of patients, genotype 3 - in 4 (16%) of them. The stage of fibrosis (F) 4 on the METAVIR scale was diagnosed in 23 (92%) patients. Patients with genotype 1b received a combination of daclatasvir with asunaprevir, and with genotype 3 - daclatasvir with sophosbuvir. In the study group 8 patients had asymptomatic MC and 17 patients had CV. Among 17 patients with vasculitis, 6 had purpura; in part - in combination with arthralgia and polyneuropathy. In 11 patients, in addition to these symptoms, internal organs, mainly the kidneys, were also affected. A sustained virologic response was in 96%. A complete clinical response in patients with CV was achieved in 67% of patiernts, and remission of glomerulonephritis was found in 56% of patients. The disappearance of cryoglobulins was observed in 29% of all cases of MC, normalization of rheumatoid factor level in 71%, and C4 complement component in 50% of patients. Daclatasvir-containing regimens for antiviral therapy of HCV-associated MC have high efficacy in eliminating of the virus, while clinical and immunological responses, especially the disappearance of cryoglobulins, have been observed less frequently. Adverse effects were minimal and very rare.
Features of erosive­ulcerative lesions of stomach and duodenum in patients with migraine
Authors: Dolgushina A. I. , Karpov M. I. , Serousova Olga V. , Osipova V. V. , Vasilenko A. F. , Markova V. V. , Mezentseva E. A.
Published: November 2020

A number of epidemiological studies have shown the Association of migraine with peptic ulcer disease (JB), however, the processes underlying the pathogenesis and features of the course of these diseases have not been fully studied. Material and methods. A comprehensive examination of the gastrointestinal tract was performed in 114 patients with migraine. Focused on the major clinical and psychological characteristics of patients depending on the availability of gastroduodenopathies, especially pain therapy and serotonin levels in the blood serum. Results. In 18.4% of patients with migraine, regardless of its type, erosive and ulcerative lesions of the stomach and duodenum were detected. In patients with chronic migraine, gastric ULCER developed more often (PF =0.022), the clinical features of the combination of migraine and ULCER were more pronounced intensity of abdominal pain and heartburn. High (5 or more times a week) frequency of nonsteroidal anti-inflammatory drugs (NSAIDs) was an important ulcerogenic factor in patients with migraine. Serotoninergic hypofunction can be discussed as a mechanism that determines the comorbid relationship of migraine and JB. The combination of migraine with NSA contributed to the formation of a more severe course of migraine. In assessing the quality of life indicators of all scales in such patients were lower . Gastropathy can be considered as an additional factor of migraine chronization, requiring appropriate therapeutic interventions to improve the quality of life of patients.
Polymorphisms of genesencoding enzymes of the xenobiotic detoxification system and the risk of infectious endocarditis
Authors: Mal’tseva Nina V. , Laputenko T. A. , Lykova O. F. , Gorbatovsky Ya. A.
Published: November 2020

Infectioue endocarditis (IE) is frequently associated with the use of narcotic drugs, glucocorticosteroids, and cytostatics that are metabolized in the body by enzymes of the xenobiotic detoxification system (XDS). This work was aimed at elucidating association between IE and mononucleotide polymorphisms of genes encoding XDS enzymes. 46 IE patients and 114 subjects without cardiovascular diseases (controls) underwent genotyping for polymorphic loci of cytochrome P450 1A1 gene I462V (CYP1A1), I105VandA114V gene of glutathione-S-transferase Pi1 (GSTP1) using allele-specific PCR. The study revealed association of CYP1A1 I462VandGSTP1 I105V with IE while IE proved unrelated to GSTP1 A114V polymorphism. Combination of homozygous variant I462I of the CYP1A1 gene and heterozygous variant I105V/ of the GSTP1 gene was associated with the 9-fold increase of the risk of IE in the subjects practicing intravenous druginjections or having congenital and acquired heart failure or implanted valve prostheses. These findings suggest the necessity of further studies on the role of XDS in pathogenesis of IE and other infectious diseases.
The prognostic value of transient arterial hypertension in patients with chronic heart insufficiency and preserved left ventricular ejection function
Authors: Serov Valery A. , Shutov A. M. , Serova D. V. , Menzorov M. V. , Kortunova M. Yu.
Published: November 2020

There is a J-like dependence of mortality among patients with chronic heart insufficiency (CHI) on arterial pressure (AP). This implies the possibility of not only elevation but also fall of AP in such patients. The aim of the study was to determine the frequency and prognostic value of arterial hypotension episodes in CHI patients with preserved left ventricular ejection function (CHI-PEF). Materials and methods. The study included 169patients (74 men and 95 women) with CHI (mean age 56,3±10,9 yr). All of them had PEF higher than 50%. 105 patients had FCII CHI, 64 ones FCIII CHI. Stage IIA was documented in 136 and stage IIB in 33 patients. Duration of the study 24 months. The combined end point included non-fatal myocardial infarction and cardiovascular death. Results. Arterial hypotension at office AP was diagnosed in 16 (9,5%) patients, transient arterial hypotension based at 24 hr AP monitoring in 104 (61,6%) patients. A total of 8 combined end points were documented during the study period. All these patients had transient systole-diastolic and/or systolic arterial hypotension . No myocardial infarction or lethal outcome developed in CHI patients without episodes of arterial hypotension (x=4,28, р=0,04). Conclusion. 24 hr AP monitoring in CHI-PEF patients permits to significantly increase the frequency of detection ofpotentially dangerous changes of AP. Transient arterial pressure occurs in 61.6% of the FCII-III CHI-PEF patients. Transient systole-diastolic arterial hypotension significantly increases the risk of non-fatal myocardial infarction and cardiovascular death in CHI-PEF patients.
Nuestra herencia maíz: Semillas nativas vs. semillas transgénicas, una aproximación desde la cultura y los derechos humanos
Authors: Ruiz Cristancho Yesica
Published: November 2020

El propósito de este artículo de reflexión es abordar la importancia de las semillas nativas de maíz frente a las semillas transgénicas. Se reflexiona al respecto de  como parte de nuestra identidad cultural, desde la tradición oral y el patrimonio material que representan, así como también desde la defensa de la seguridad alimentaria son  parte fundamental de los derechos humanos. Se destacan los aportes que desde el arte y la cultura, permiten generar espacios de resistencia que permitan mantener vivas tradiciones, valores y prácticas, que rondan el cultivo ancestral del maíz por parte de las comunidades, indígenas, campesinas, afro, etc.
Na-dominant (at the M2 site) eudialyte analogue: crystal structure and indicatory significance
Authors:   Institute of Crystallography FSRC, Rastsvetaeva R. K. , Chukanov N. V. ,   Moscow State University, Schäfer Ch.
Published: November 2020

Minerals of the eudialyte group from ultra-agpaitic associations are often characterized by high contents (up to the dominance) of sodium at the M2 site, which is populated with iron in eudialyte. The features of blocky isomorphism with the replacement of IVFe2+ by IVNa and VNa at the M2 micro-region are discussed. Using the methods of electron probe microanalysis, X-ray diffraction and IR spectroscopy, a potentially new mineral, M2Na-dominant analogue of eudialyte from the Ilimaussaq alkaline massif (Greenland), was investigated. Its crystal structure was refined to R = 5.6 % in the anisotropic approximation of atomic displacements using 1095 independent reflections with F > 3(F). The unit-cell parameters are: a = 14.208(1), c = 30.438(1) Å, V = 5321(1) Å3; the space group is R-3m. The idealized formula of the mineral is (Z = 3): (Na,H3O)15Ca6Zr3[Na2Fe][Si26O72](OH)2Cl∙2H2O.
THE METHOD PROBLEM IN THE CONTEXT OF PSYCHOLOGICAL KNOWLEDGE INTEGRATION
Authors:   Institute of psychology named after G. S. Kostyuk of NAPN of Ukraine, Medintsev Vladislav A.
Published: November 2020

In psychological science, the «method problem» remains one of the most fundamental and relevant, and a new content shade of this problem is associated with the activation of discussion on the psychological knowledge integration. In this context, the problem acquires an updated content as a problem of a universal method in psychology. There is a reason to believe that the «method problem» is transformed into the «universal method problem» and then into the «universal method integration problem». The efforts to solve these problems are often depreciated due to the ignorance of experimenting and practicing psychologists by methodological knowledge. The possible way to build a universal method for theoretical research in psychology is to use for this purpose a procedural interpretation of theorizing based on set-theoretic process description method. In the article components of theoretical research are considered as the purpose, object, subject, hypothesis of the research, as well as the considered empiricism, theoretical foundations, method of theorizing and research tasks. Two methodological «poles» of theoretical research are identified – the «normative» method and modern research methods, and a variant of analyzing their structures is proposed. To create a universal method suitable for psychological knowledge integration is associated with obstacles, which can be overcome by their systematic analysis. The article outlines a variant of this analysis, in which the causes and sources of these obstacles are differentiated based on the system of concepts used for describing processes. The sources of integration obstacles include components of prototype modi, and the causes are properties of modi functions in the recording of processes as maps of sets. The examples describe the integration obstacles at the two levels of interactions.
SCHOOL MEDIATION AS A RESOURCE FOR DEVELOPING A TEENAGER'S COMMUNICATION SKILLS
Authors:   Yaroslavl state pedagogical university named after K. D. Ushinsky, Yuferova Marina A.
Published: November 2020

The article focuses on the problem of the need to develop the communicative abilities of adolescents in highly conflicted educational environment. There is a tendency to increase cases of active intervention of parents in school conflicts in order to protect the interests of their children, which is not infrequently an obstacle to a child's experience of interpersonal interaction based on their own resources. The ability to overcome interpersonal contradictions, restore and maintain constructive communication in conflict situations is an important task of personal development at the stage of adolescence. Communication difficulties experienced subjectively by adolescents can lead to potentially conflicting patterns of behavior – avoiding contact or displaying authoritarianism in communication. Their overcoming is possible by expanding the communicative experience and behavioral repertoire of adolescents in conflict situations. The organization and activity of school mediation services for the purpose of mediation in conflicts is an opportunity for teenagers to gain experience in negotiations, develop communication skills, and form a culture of constructive communication. The author notes that mediation has a great communicative potential: through mastering the techniques of active listening, conducting partner conversations, and feedback, the mediator creates an atmosphere of correct, business-like, and rational discussion of controversial issues. Speech strategies of «mitigation», «control over the topic», «joint search for an alternative», various tactics of raising questions, allow the parties to the conflict to activate the state of reflection and turn to the analysis of their true interests in the conflict. The article presents the experience of organizing mediation training for teenagers on the basis of the municipal resource center «League of young mediators» in Yaroslavl, during which statistically significant positive results were obtained in the development of students ' communicative abilities
PSYCHOLOGICAL ASPECTS OF USING BIG DATA TECHNOLOGY IN THE CONTEXT OF DISTANCE LEARNING
Authors:   Yaroslavl state pedagogical university named after K. D. Ushinsky, Bugaichuk Tatiyana V. , Polyakova Polina A. ,   Yaroslavl state pedagogical university named after K. D. Ushinsky
Published: November 2020

The issue of studying a person's abilities to perceive a large amount of information during the period of distance learning is poorly understood and extremely relevant. The problem of our research is the identification of modern technologies for supporting education system specialists in working with a large amount of information, the ability to perceive and analyze it, as well as reducing the level of information fatigue among educational workers during distance learning, since the digitalization of education has an intense negative impact on mental processes of employees, on their psychological and social well-being. The article describes the results of a theoretical study of the interdisciplinary convergence of the indicated problem, expanding the understanding of Big Data technology through the psychology of abilities and the psychology of education. At the same time, the authors of the article note the increasing role of Big Data technology in the modern conditions of a pandemic and distance learning. Big Data technology or «Big Data» means a certain system of methods and some algorithms for working with large amounts of data. These data sets are aimed at acquiring a qualitatively new understanding of what this information carries. Now there are four main directions of the formation of large volumes of data in the education system. These are online training systems, internal information systems of educational organizations, information about employees and the requirements of the organization's management to potential employees, information about students. Having studied the main directions of Big Data development when processing large amounts of various information, we found links with the implementation of Big Data methods, tools and technologies in the field of education and the efficiency of employees. The authors identified and studied an important function of Big Data in the period of distance learning – it is the creation of psychological well-being of employees of the education system and the leveling of the problem of information fatigue.
SOVIET EXISTENCE AS AN INTEGRATIVE PHENOMENON: ORIGINS, TRANSFORMATION, ARTISTIC PRACTICES
Authors:   Yaroslavl state pedagogical university named after K. D. Ushinsky, Zlotnikova Tatiyana S. , Erokhina Tatiyana I. ,   FSBEI HE «Yaroslavl state theatrical institute», Eriomin Aleksandr V. ,   Yaroslavl state pedagogical university named after K. D. Ushinsky
Published: November 2020

The article summarizes the scientific problems that became the subject of the seminar-discussion «Soviet existence on the eve of the formation of a totalitarian and authoritarian framework» (May 2020), conducted by members of the research team of the Russian science Foundation grant № 20-68-46013. The team of authors consisting of leading scientists (doctors of sciences and young researchers (PhD and graduate students) presented the results of a research grant, applying to the disclosure of the origins of the concept «soviet existence», to understanding the content of an integrative phenomenon of soviet being and its representation in artistic practice. On the basis of the conducted collective research, the primary concepts of Russian culture of the XIX and XX centuries are analyzed, which allowed us to find a certain continuity of semantic complexes, spiritual, historical and political prerequisites and realities, artistic creativity and everyday practices of the pre-soviet and soviet periods of russian culture. The soviet being is designated as a living and paradoxical space, which is reflected in the works of representatives of soviet culture, religious and pseudo-religious practices, metamorphoses and transformations of the daily (everyday) existence of the individual. Special attention is paid to the representation of soviet existence in artistic creativity, the evolution and transformation of ideas about the existence of the individual in works of different types of art. There are designated the main trends of perception of the real and ideal world, the circle of characters (images) and their symbolic interpretation, basic plots and themes. The article presents the content of the research conducted under the grant, also it outlines theoretical and methodological approaches to further understanding the phenomenon of «soviet existence» in philosophical, historical, cultural and artistic discourses.
A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
Authors: Horta Alexandra Bayão , Geraldes Carlos , Salgado Cátia , Vieira Susana , Xavier Miguel , Papoila Ana Luísa
Published: November 2020

Introduction: Increased life expectancy leads to older and frailer surgical patients. Co-management between medical and surgical specialities has proven favourable in complex situations. Selection of patients for co-management is full of difficulties. The aim of this study was to develop a clinical decision support tool to select surgical patients for co-management.Material and Methods: Clinical data was collected from patient electronic health records with an ICD-9 code for colorectal surgery from January 2012 to December 2015 at a hospital in Lisbon. The outcome variable consists in co-management signalling. A dataset from 344 patients was used to develop the prediction model and a second data set from 168 patients was used for external validation.Results: Using logistic regression modelling the authors built a five variable (age, burden of comorbidities, ASA-PS status, surgical risk and recovery time) predictive referral model for co-management. This model has an area under the curve (AUC) of 0.86 (95% CI: 0.81 - 0.90), a predictive Brier score of 0.11, a sensitivity of 0.80, a specificity of 0.82 and an accuracy of 81.3%.Discussion: Early referral of high-risk patients may be valuable to guide the decision on the best level of post-operative clinical care. We developed a simple bedside decision tool with a good discriminatory and predictive performance in order to select patients for comanagement.Conclusion: A simple bed-side clinical decision support tool of patients for co-management is viable, leading to potential improvement in early recognition and management of postoperative complications and reducing the ‘failure to rescue’. Generalizability to other clinical settings requires adequate customization and validation.
SEMANTIC GESTALT OF THE KERNEL OF LANGUAGE CONSCIOUSNESS OF BURYAT-BILINGUALS
Authors:   Institute for Mongolian, Buddhist and Tibetan Studies of the Siberian Branch of the Russian Academy of Science, Dyrkheeva G.A.
Published: November 2020

The article is devoted to the experience of the comparative analysis of language consciousness content of the Buryat-bilinguals on the example of a semantic Gestalt of basic fields of people, home, life presented in the Buryat and Russian languages. The main aim of the research is identification of ethnocultural specifics and transformation of language consciousness of modern Buryat-bilinguals, knowing Russian and the Buryat language. The analysis is carried out on the basis of the associative dictionary made by the author of the article. The results of the experiment show that semantic zones of both Gestalts in many respects are identical, consisting of five-eight zones of the same name, however their content and hierarchy of arrangement reveal essential differences in images of consciousness of the Buryat-bilinguals - the carriers of two languages. It was confirmed that for the Buryats in their native language a basic valuable dominant is the family. The main differences in the content of knowledge in different languages in many respects are defined by system and structural features of language and a discrepancy of semantic fields. Buryats’ active assimilating Russian led both to assimilation of new lexicon, and to assimilation of the corresponding lexical stereotypes. It is undoubted that foreign-language influence promotes changes in lexical structure and communicative standards of the Buryat language, it transforms its system of culture and valuable. The received results may be used in social-, psycholinguistic researches, linguistics of language contacts.
MEDIA REPRESENTATIONS OF DOMESTIC VIOLENCE: GENDER DIMENSION
Authors:   National Research University Higher School of Economics, Gritsenko E.S.
Published: November 2020

The paper focuses on the discourse surrounding a resonate media event connected with the discussion of contested statements concerning domestic violence made by a popular Russian TV-host and blogger. We use feminist critical discourse analysis and analysis of the sociocultural context of discourse to explore the strategies employed to resolve the conflict and highlight the ways global discourses on gender and violence are localized. We show how linguistic representations promote abuse-sustaining discourses or question the gendered ideologies of male violence against women and challenge the social system that condones gender-based violence. The study revealed heterogeneity of gender attitudes, varying (gender-based) degrees of tolerance to statements about domestic violence, the ineffectiveness of the appeal to Anglophone discourses on gender and the effectiveness of a strategy based on the knowledge and experience of “one’s own” social culture. The persistence of patriarchal values in the discourse on domestic violence is supported by widely used strategies of degendering the violence and gendering the blame.
ENGLISH PHRASEOLOGICAL UNITS: SECONDARY INTERPRETATION OF KNOWLEDGE ABOUT SOCIAL RELATIONS
Authors:   Derzhavin Tambov State University, Babina L.V. , Dolgova E.V. ,   Derzhavin Tambov State University
Published: November 2020

The article deals with phraseological units (hereinafter - PU) of the English language containing somatisms, names of food, clothes and furniture, transmitting information about social relations. It is noted that PU are the result of secondary interpretation of knowledge, which leads to the cognitive models of their semantics formation being considered. The main research method is cognitive modeling. The authors reveal that in the course of secondary understanding of information about social relations, metaphorical, metonymic and metaphtonymic cognitive models can be involved. The research shows that when forming the semantics of PU transmitting information about social relations, the metaphorical model SOCIAL - PHYSICAL, MENTAL - PHYSICAL, as well as the models HUMAN BEING - ANIMAL (insect), HUMAN BEING (head) - CONTAINER can be used in the process of secondary interpretation. Metaphorical projection can be based on the following main characteristics: feature and action. The metonymic models involved are PART1 (product) - PART2 (producer), PART (specific manifestation) - WHOLE (phenomenon), PART1 (workplace) - PART2 (position associated with the workplace), PART1 (body part) - PART2 (external manifestation of an emotion), PART2 (cause) - PART1 (effect). The interaction of the EMOTIONAL - PHYSICAL metaphorical model and the PART1 (organ) - PART2 (functional significance) metonymic model was revealed in the metaphtonymic understanding of information about social relations.
POLITICAL METAPHOROLOGY AT THE PRESENT STAGE OF DEVELOPMENT (2010-2019)
Authors:   Russian State Vocational Pedagogical University, Budaev E.V. , Chudinov A.P. ,   Ural State Pedagogical University
Published: November 2020

The article deals with the major trends of modern political metaphorology (2010-2019): cognitive (considering a political metaphor as a mental phenomenon); rhetorical (focused on the analysis of political metaphor as a pragmatic mechanism of influence on the addressee); discursive (exploring a metaphor in a broad extralinguistic context in different types of political discourse); semiotic (studying metaphor and especially non-verbal representations of metaphor as a special sign system reflecting the political life of society). The leading trends in the development of modern political metaphorology reflect general trends characteristic of non-classical science (the growth of interdisciplinarity, methodological pluralism, criticism of universalism and increased attention to the national-cultural specifics of communication). Russian and foreign linguistics are characterized by growing tendency of combining both discursive and cognitive characteristics of political communication, which leads to overcoming the traditional contrast between cognitive and discursive directions for political linguistics, as well as to the convergence of rhetorical (stylistic) and cognitive approaches.
A COGNITIVE THEORETICAL INVESTIGATION OF CONCEPTUALIZING HINDI SARCASM
Authors:   Department of Humanities and Social Sciences, Sandeep Kumar Sharma ,   Indian Institute of Technology, Sweta Sinha ,   Department of Humanities and Social Sciences; Indian Institute of Technology
Published: November 2020

Several influential theories have been developed in cognitive linguistics to investigate the relationship between language and mind. Conceptual metaphor and conceptual blending, two distinct but closely related theories play a significant role in the process of meaning construction especially in metaphors and other figurative linguistic tools. Metaphors are pervasively used in everyday conversation in the form of irony, satire and sarcasm, etc. where sarcasm projects profoundly negative intention. Hence, the present research studies the process of conceptualization of sarcasm and its functions with special reference to the Hindi language within the framework of conceptual metaphor and conceptual blending theories. The study is an attempt to bridge the gap between computational studies of sarcasm and the theories underlying the phenomenon of perceiving sarcasm. The findings aim to provide a theoretical understanding of how Hindi sarcasm is perceived among native speakers.
Working and Non-Working Learners in Math: Basis for Utilizing Strategic Intervention Materials
Authors: Diaz Rowell , Diaz Elizabeth , Gabriel Eloisa , Sison Maricar
Published: November 2020

: The performance of the students in academics depends on many different factors. One of these factors is the economic status of their families. Education in public schools, though it is free, some parents cannot afford to send their children to school due to financial constraints. Education as a free is every individual's right in society, but it becomes a privilege because of a lack of financial support. This research work is a comparative study of students' or learners' performance in mathematics among students from working and non-working. This research article's ultimate objective is to investigate and compare a significant difference in their performance in the subject mathematics. The research methodology utilizes a t-test to analyze and synthesize primary data sources collected via interview and academic records, and diverse literature on the study area. However, the research findings revealed no significant difference in the two groups (the working and non-working group of learners). Therefore, it is recommended that secondary schools should be provided with adequate books and facilities and faculty school interventions and programs and promote the usage of SIM or Strategic Intervention Materials for learning and memory enhancement among learners.