bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the Role of Antioxidants to Combat Oxidative Stress in Malaria
Parasites
Authors: Nandi Sisir , Ahmed Sarfaraz , Saxena Anil Kumar
Published: April 2022

Background:

Malaria, a global challenge, is a parasitic disease caused by Plasmodium species. Approximately 229 million cases of malaria were reported in 2019. Major incidences occur in various continents, including African and Eastern Mediterranean Continents and South-East Asia.

Introduction:

Despite the overall decline in global incidence from 2010 to 2018, the rate of decline has been almost constant since 2014. The morbidity and mortality have been accelerated due to re-active oxygen species (ROS) caused by oxidative stress generated by the parasite responsible for the destruction of host metabolism and cell nutrients.

Methods:

The excessive release of free radicals is associated with the infection in the animal or human body by the parasites. This may be related to a reduction in nutrients required for the genera-tion of antioxidants and the destruction of cells by parasite activity. Therefore, an intensive litera-ture search has been carried out to find the natural antioxidants used to neutralize the free radicals generated during malarial infection.

Results:

The natural antioxidants may be useful as an adjuvant treatment along with the antimalarial chemotherapeutics to reduce the death rate and enhance the success rate of malaria treatment.

Conclusion:

In this manuscript, an attempt has been made to provide significant insight into the an-tioxidant activities of herbal extracts against malaria parasites.
DFT Study of the Possible Reaction Path for Radical Promoted Esterification Mechanism of Free Fatty Acids of Soapnut Oil for the Production of Biodiesel
Authors: Ghani Naila , Kosar Naveen , Sadaf Sana , Mahmood Tariq , Khalid Muhammad , Ayub Khurshid , Iqbal Javed , Noor Sadia
Published: April 2022

Esterification of higher free fatty acids content by using a photo-catalyst has recently been proved as the most efficient method for the pretreatment of non-edible oil to synthesize biodiesel.

Methods:

In the current study, mechanistic details of photo-catalyzed esterification reaction for four different fatty acids through density functional theory (DFT) calculations are explored and compared with un-catalyzed esterification reaction.

Results:

Revealed that the presence of photo-catalyst lowers the activation barrier and the structure of fatty acid has no significant effect on its reactivity. Thermodynamic data also revealed that the presence of photo-catalyst lowered the activation energy from 51.67 kcal/mol to 0.7495 kcal/mol. Furthermore, Gibbs free energy changes (ΔrGm Ø) and molar enthalpy changes (ΔrHm Ø) of the photo-catalyzed esterification reaction are negative, indicating that it is a spontaneous exothermic reaction. On the other hand, free fatty acids esterification in the absence of a catalyst is a kinetically unfavorable process with positive values of ΔrGm Ø and ΔrHm Ø.

Conclusion:

Our findings theoretically clarify the mechanism of the photo-catalyzed esterification reaction of FFA present in non-edible oil, which facilitates the process of biodiesel production.
Disparity and Factors Associated With Internet Health Information Seeking Among US Adults Living With Diabetes Mellitus: Cross-sectional Study
Authors: Eke Ransome , Jannat Khadiza Tul , Yang Xin Thomas , Parton Jason M
Published: April 2022

Background

Many patients with chronic medical conditions search the internet to obtain medical advice and health information to improve their health condition and quality of life. Diabetes is a common chronic disease that disproportionately affects different race and ethnicity groups in the United States. In the existing literature on the popularity of internet health information seeking among persons with a chronic medical condition, there are limited data on US adults living with diabetes.

Objective

This study aims to examine the factors associated with internet health information seeking among US adults living with diabetes and whether there is a disparity in internet health information seeking stratified by race and ethnicity.

Methods

We conducted a cross-sectional study using the Health Information National Trends Survey data from 2017 to 2020. We selected our study sample based on respondents’ reports on whether they were told they had diabetes, and our primary outcome was internet health information–seeking behavior. We used 2 multivariable logistic regression models to examine the effects of sociodemographic factors and other covariates on the internet health information–seeking behavior of adults with diabetes. Jackknife replicate weights were used to provide bias-corrected variance estimates.

Results

Our study sample included 2903 adults who self-reported that they had diabetes. In total, 60.08% (1744/2903) were non-Hispanic White individuals, 46.88% (1336/2850) were men, and 64% (1812/2831) had some college or graduate education. The prevalence of internet health information seeking in this population was 64.49% (1872/2903), and the main factors associated with internet health information seeking included education level (some college vs less than high school: odds ratio [OR] 1.42, 95% CI 1.44-1.88; and college graduate or higher vs less than high school: OR 2.50, 95% CI 1.79-3.50), age (age group ≥65 years vs age group 18-44 years: OR 0.46, 95% CI 0.34-0.63), and household income level (P<.001). In addition, we found significant differences in the effects of predictors stratified by race.

Conclusions

The findings from this study suggest that internet health information seeking is common among US adults living with diabetes. Internet health information could influence the relationship between health care providers and adults living with diabetes and improve their self-management and quality of life.
Reduction of SARS-CoV-2 Viral Load by Photodynamic Therapy (PDT) Verified by QPCR – A Novel Approach to Treat Patients in Early Infection Stages (Preprint)
Authors: Weber Michael
Published: April 2022

BACKGROUND

The current Covid-19 pandemic is affecting the life of many people worldwide, and although the search for vaccines has made fast progress, there is at the moment no effective medication available. This article explores the usage of Riboflavin (Vitamin B2) in combination with blue and ultraviolet light, which is known to be one of the best photosensitzers for anti-viral Photodynamic Therapy (aPDT).

OBJECTIVE

----

METHODS

It proposes a new treatment system with a LASER/LED treatment device combined with blue and UVA light therapy. It is interventional non-randomized study in 140 subjects. Participants were allocated to receive either photodynamic therapy plus daily testing for 5 days or to receive conventional care plus testing. Viral load and clinical symptoms were measured at the start of the study and after 24, 48, 72, 96, 120 and 168 hours.

RESULTS

A simple Welch t-test for two samples indicate a difference of 6.68 thresholds in the means of viral load values, with a confidence interval of [5.2; 8.72], p<0.01. The same test shows no significance in the difference in the means of the control group.

CONCLUSIONS

aPDT decreases viral load in patients in early stages of COVID-19.

CLINICALTRIAL

Study plan and design can be reviewd on link below of the study registration
ISRCTN registry with study ID ISRCTN10839729
https://www.isrctn.com/ISRCTN10839729
Auto Indoor Hydro Phonic Fodder Grow Chamber
Authors: Madne Prof. A. N. , Moon Vazira , Gautre Mohit , Selokar Sameer , Bhimte Ashish , Sayankar Vaibhav , Watekar Kaustubh
Published: April 2022

Abstract 1) Hydroponics is changing the agriculture industry slowly. the ability to grow indoor brings another dimension to agriculture. We have develop a mini fodder grow chamber, they aregrow a fodder within week, 2) A chamber maintain a temperature and moisture monitoring to ensure proper indoor growconditions for a good growth. 3) The system makes use of arduino controller and many more senser to control temperaturemoisture. 4) The system use the motor to ensure water level, pump motor and adjust water level motorssome types of motor are use for maintain water level in chamber. 5) 5 ) In chamber we use artificial sunlight is switched on and off as per use. 6) In this chamber water are circulate in water pump and also added a some nutrient in wateralso. And fan work at a maintain a surrounding atmospheric air.
Pemanfaatan Sumber Air Baku Pegunungan Menjadi Air Minum Dengan Metode Filterisasi dan Sterilisasi di Dusun Cisoka
Authors: Dharmosmoedero Djati Poetryono , Soecahyadi Soecahyadi , Sulistyadi Kohar
Published: April 2022

Perekonomian warga Dusun Cisoka sebagai pemetik daun teh. Permasalahan yang dialami warga Dusun adalah, panen kebun teh hanya dapat dilaksanakan selama 3 bulan sekali. Dari hasil panen itupun warga masyarakat Dusun, belum dapat memenuhi kebutuhan hidup selama menunggu panen selanjutnya. Disamping itu juga, masyarakat tidak memiliki penghasilan maupun kegiatan lain yang dijalankan karena hingga saat ini, warga Dusun belum mendapatkan pasokan listrik dari negara.Namun ditengah keterbatasan, Dusun Cisoka memiliki potensi sumber mata air yang berasal dari perbukitan dan kualitasnya baik.Melalui kegiatan pengabdian masyarakat yang dilaksanakan oleh tim PKM Usahid, menghasilkan : 1) Sebuah instalasi Pengolahan air baku menjadi air minum isi ulang yang siap dikonsumsi yang berupa Depot Air Minum (DAM); 2) Peningkatan pemahaman masyarakat Dusun mengenai pemanfaatan mata air pengunungan yang dimiliki untuk diproduksi menjadi air isi ulang ke masyarakat luas; 3) Pendapatan ekonomi masyarakat melalui pemanfaatan DAM; 4) Peningkatan kemampuan manajerial dalam mengelola usaha DAM.
Penyuluhan Pemanfaatan Sosial Media Sebagai Sarana Menjadi Technopreneur Bagi Generasi Milenial
Authors: Gumilang Ridwan Khanang
Published: April 2022

Globalisasi ekonomi dan era informasi mendorong industri menggunakan sumber daya manusia generasi milenial yang kompeten dan memiliki jiwa entrepreneurship. Namun masih sedikit generasi milenial yang memiliki jiwa enterpreneurship. Kenyataan menunjukkan bahwa hanya sebagian kecil generasi milineal memiliki jiwa enterpreneurship. Di sisi lain, krisis ekonomi menyebabkan jumlah lapangan kerja tidak tumbuh, dan bahkan berkurang karena bangkrut. Dalam kondisi seperti ini, generasi milenial dituntut untuk tidak hanya mampu berperan sebagai pencari kerja tetapi juga harus mampu berperan sebagai pencipta kerja. Keduanya memerlukan jiwa enterpreneurship. Agar masyarakat mampu memenuhi tuntutan tersebut, berbagai inovasi diperlukan. Diantaranya adalah inovasi pembelajaran dalam membangun generasi technopreneurship. Ada suatu pendapat bahwa saat ini sebagian besar lulusan perguruan tinggi di Indonesia masih lemah jiwa enterpreneurship. Dalam kenyataan menunjukkan bahwa enterpreneurship merupakan jiwa yang bisa dipelajari dan diajarkan. Seseorang yang memiliki jiwa enterpreneurship umumnya memiliki potensi menjadi pengusaha tetapi bukan jaminan menjadi pengusaha, dan pengusaha umumnya memiliki jiwa entrepreneurship.
Pemanfaatan Biji Kopi dan Jahe Sebagai Sediaan Footsanitizer Untuk Menambah Pengetahuan Kesehatan Bekerja Sama Dengan Penggerak PKK Kelurahan Panggung
Authors: Febriyanti Rizki , Purgiyanti Purgiyanti , Prabandari Sari
Published: April 2022

Pemberdayaan masyarakat pada dasarnya merupakan kegiatan terencana dan kolektif dalam memperbaiki kehidupan masyarakat yang dilakukan melalui program peningkatan kapasitas orang, terutama kelompok lemah atau kurang beruntung (disadvantages groups) agar memiliki kemampuan dalam memenuhi kebutuhan dasarnya mengemukakan gagasan, melakukan pilihan-pilihan hidup, melaksanakan kegiatan ekonomi, menjangkau dan memobilisasi sumber, serta berpartisipasi dalam kegiatan sosial.Tujuan dari kegiatan pengabdian kepada masyarakat ini yaitu untuk menambah pengetahuan masyarakat melalui kader dari Penggerak PKK Kelurahan Panggung tentang kepedulian memanfaatkan limbah sebagai jalan keluar untuk menambah nilai perekonomian.Dari kegiataan PKM yang sudah dilaksanakan dapat ditarik kesimpulan bahwa peningkatan pengetahauan, pemahaman dan pelatihan mengenai produk footsanitizer ekstrak biji kopi dan jahe dengan  beberapa konsep yang diberikan meliputi : penyuluhan tentang manfaat penggunaan footsnitizer, mengolah pembuatan footsanitizer dari ekstrak biji kopi bagi Penggerak PKK Kelurahan Panggung sesuai dengan tingkat ilmu yang mudah dipahami oleh mereka.
Penyuluhan Kegiatan Perilaku Hidup Bersih dan Sehat (PHBS) kepada Siswa Kelompok Bermain BAIPAS CERIA, Kota Malang dalam Upaya Pencegahan Penularan COVID-19 di Lingkungan Siswa
Authors: Hasna Tanalyna , Putri Aulia Latifa , Putri Aulia Latifa , Muchlisyiyah Jhauharotul , Muchlisyiyah Jhauharotul , Zamzami Abid
Published: April 2022

COVID-19 is a pandemic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection that infects the respiratory tract of the sufferer. The disease can be transmitted through splashing when talking, sneezing, cough, and is also transmitted through intense physical contact (face, mouth, nose). In daily activities, children are suspected to have not been so aware of the threat of COVID-19 transmission around it, especially if it is not equaled by knowledge and self-awareness of the important role of maintaining cleanliness and self-health. Thus, the extension of PHBS in schools is one of the initial efforts to empower teachers and students, as well as the community environment around the school to be self-aware and willing to familiarize clean and healthy living behaviors to create a healthy school environment.COVID-19 merupakan penyakit pandemik yang disebabkan oleh infeksi virus severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) yang menginfeksi saluran nafas penderitanya. Penyakit ini dapat menular melalui percikan pada saat berbicara, bersin, batuk dan juga ditularkan melalui kontak fisik yang intens (wajah, mulut, hidung). Dalam aktivitas sehari-hari, anak-anak diduga belum begitu memperhatikan akan adanya ancaman penularan COVID-19 di sekitarnya, terlebih jika tidak dibersamai dengan pengetahuan dan kesadaran diri terhadap peran penting dari menjaga kebersihan dan kesehatan diri. Maka, penyuluhan PHBS di sekolah merupakah salah satu upaya awal untuk memberdayakan guru dan siswa, juga lingkungan masyarakat sekitar sekolah agar sadar diri dan mau membiasakan perilaku hidup bersih dan sehat guna menciptakan lingkungan sekolahan yang sehat.
Influence of Fiscal Decentralisation and Ethnic Diversity on Educational Outcomes – Evidence from Indonesia
Authors: Siburian Matondang Elsa
Published: April 2022

The main objective of this paper is to clarify the influence of fiscal decentralisation and ethnic diversity on Indonesia’s educational outcomes using Indonesian provincial-level data from 2001 to 2014 and applying dynamic panel data estimation. This paper takes into account that ethnic diversity mediates the relationship between fiscal decentralisation and educational outcomes. The result confirms that the inclusion of the ethnic diversity variable lessens the positive influence of fiscal decentralisation on educational outcomes. The presence of a diversity debit hypothesis in Indonesia overshadowed the local government’s effort in improving regional educational outcomes through decentralisation. This paper proposes a set of policy recommendations based on empirical results to assist the local government in controlling the adverse effect of ethnic diversity on regional educational outcomes.
LABOUR–SPECIFIC FACTORS INFLUENCING THE VOLUME OF CONSTRUCTION WASTE GENERATION IN THE CONSTRUCTION INDUSTRY
Authors: EZE Emmanuel Chidiebere , AWODELE Imoleayo Abraham , EGWUNATUM Samuel Ikechukwu
Published: April 2022

The construction industry generates a large volume of waste which distorts the aesthetics of the environment and contributes to the impediments to achieving social, economic and environmental dimensions of sustainability. Construction waste impact project schedule, cost, and derails contractor's profit, leads to claims and disputes. Construction tradespeople who are the frontline workers have a role to play in the waste generation of construction projects irrespective of the level of development of a nation. This study assessed the labour-specific factors influencing construction wastes generation on construction projects in Nigeria. The well-structured questionnaire conveniently administered to construction tradespeople in active construction sites in Port Harcourt was used to gathered data. Garnered data were analysed using the mean item score and Kruskal-Wallis H tests. The study found that the most significant labour-specific factor that influence construction waste generation are workers' mistakes/errors leading to rework, poor attitudes of workers, shortage of skilled workers/use of unskilled, poor workmanship, and lack of experience. The study recommended for the organisation of adequate training to improved workers knowledge and skills needed to execute projects tasks.
The US Dollar as the Global Currency Against Other Major Currencies During the Covid-19 Pandemic
Authors: Bukari Muhammad Fahmi
Published: April 2022

The dominance of the US Dollar in the international economy began with the Bretton Woods system at the end of World War II in 1945. The currencies from other major economic powers such as the Eurozone’s Euro, the Japanese Yen, and the Chinese Yuan could be the best contenders against the US Dollar supremacy in the 21st century. The most popular cryptocurrency – Bitcoin, also eyes the position as a contender for the global currency. The COVID-19 pandemic has disrupted the global economy in 2020. As a result, the reliability and popularity of the US Dollar have been put into another stress test. To measure the status of the US Dollar against other major currencies, the theory of international political economy paired with graph analysis will be used to determine the strength of the US Dollar against other major currencies. This paper also looks at the value of the US Dollar against the cryptocurrency Bitcoin. It is assumed that graph movement is influenced by the market sentiment after receiving news and information that could affect the market.
Universidade e roça: saberes na encruzilhada
Authors: Macêdo Maria Dalva de Lima
Published: April 2022

O artigo é parte da tese de doutoramento que trata da relação entre roça e universidade na contemporaneidade, nos sertões da Bahia. Objetiva responder qual o impacto da universidade na roça, no tocante aos processos de desterritorialização/reterritorialização versus políticas de “fixação do homem ao campo”. Fundamentada na História Oral e em Epistemologias do Sul, apresenta a escrita a partir do diálogo entre teoria e experiência, tendo as narrativas dos entrevistados como fonte principal, e, de forma metafórica, compara o acesso à universidade a curva e a encruzilhada do caminho. A relação entre universidade e roça é avaliada pelo duplo movimento de oferta e acesso efetuado respectivamente, pela universidade e pela roça. Neste contexto, a multicampia representa um ganho para a roça, contudo, exige o deslocamento dos corpos da roça até a universidade. A roça não é visível para a universidade, ao contrário, ambas se encontram em lados opostos da linha abissal que separa o conhecimento em válido (universidade) e invisível (roça). Validar o conhecimento produzido e reproduzido pela roça, multiterritorializando e/ou descolonizando corpos e a própria roça, constitui o desafio da relação entre roça e universidade.
As políticas neoliberais para a educação superior no Brasil na perspectiva dos planos de governo brasileiro (1994-2018)
Authors: Francisco João Felipe Nascimento
Published: April 2022

O presente artigo objetiva discorrer sobre as políticas educacionais para Ensino Superior e mudanças efetivadas no período de 1994 até 2018, sob a indagação da contradição da vertente neoliberal dos planos de governo deste período e o avanço de políticas públicas em alguns governos. Foi realizado um estudo bibliográfico partindo da análise dos planos de governos apresentados pelos presidentes, sob o enfoque econômico, situado na aplicabilidade do modelo neoliberal para as políticas de Estado, bem como o contexto político, através da metodologia de análise política de ciclos nos projetos de governo que após a ruptura política e econômica com o golpe institucional de 2016, há uma retomada da agenda ultraliberal no Brasil, que previa uma abertura econômica para a competitividade internacional, privatização de estatais, desenvolvimento centrado no investimento da iniciativa privada e na educação estabelece prioridade no ensino básico e acenava para uma reforma no ensino superior público e trazia objetivamente uma nova política de fortalecimento do ensino superior privado.
Formação de gestores educacional em mobilização social
Authors: Fattori Camila Campos Tinoco , Teixeira Maria da Glória Gonçalves , Pereira Maria Regina dos Passos , Panico Roberta Leite
Published: April 2022

Este artigo de campo, resultado de pesquisa de natureza empírica, trata de uma experiência de formação - parte de um programa em realização - de Técnicos da Secretaria de Educação de diversas localidades para atuarem como agentes de mobilização social. Tal formação está baseada no estudo e em experiências práticas que favorecem  a reflexão sobre as concepções de mobilização social e de formação de Redes Sociais como uma alternativa para que diferentes atores da sociedade possam atuar em prol de questões complexas e policausais como a Educação. A prática se dá por meio de encontros formativos e pela experiência da participação desses técnicos como integrantes e facilitadores de Redes Sociais, atuando em conjunto com diversos atores da sociedade civil. Nas Redes Sociais são desenvolvidas ações  que contribuem para a educação pública de qualidade, com a mediação de formadores. O artigo apresenta a experiência de trabalho da Comunidade Educativa CEDAC no contexto de parceria técnica no programa Parceria pela Valorização da Educação (PVE) promovido pelo Instituto Votorantim em parceria com Secretarias Municipais de Educação. Busca sistematizar algumas estratégias formativas e analisar os efeitos desse trabalho na participação social na educação e também na abertura das Gestões Educacionais para atuar em parcerias dentro da proposta de uma gestão democrática. Destaca o princípio de ação-reflexão-ação e a atuação conjunta entre técnico mobilizador e formador como aspectos chave da formação.
Response to Letter to the Editor regarding ‘Characteristics and outcomes of ventricular tachycardia and premature ventricular contractions ablation in patients with prior mitral valve surgery’
Authors: Khalil Fouad , Killu Ammar
Published: April 2022

We would like to thank the authors for their letter and interest in our
manuscript. We appreciate their valuable comments. The authors have
raised the following important points: 1. The heterogenicity of our
cohort with mitral valve surgery (MVS) 2. Elucidating the
characteristics and causes of ventricular arrhythmias (VA) in patients
with primary versus secondary mitral disease as well as in those with
ischemic versus non-ischemic heart disease 3. The paucity of cardiac
magnetic resonance imaging (MRI) as a limitation of the study 4. The
need for careful evaluation of patients prior to ablation since most
arrhythmias did not originate from the perimitral area.
VENDOR INDEPENDENT MYOCARDIAL STRAIN REFERENCE VALUES IN CHILDREN
Authors: Acheampong Benjamin , Parra David , Havens Corey , Jantzen David , Godown Justin , Soslow Jonathan
Published: April 2022

Background Two-dimensional (2D) strain imaging has become an
important tool in assessing subclinical myocardial dysfunction in
children. However, there are no pediatric reference values for vendor
independent strain software. The aim of this study was to estimate 2D
strain values in a cohort of healthy children using Tomtec cardiac
performance analysis (CPA), a vendor independent software.
Methods Transthoracic echocardiograms of healthy pediatric
outpatients (0-18yrs) were retrospectively analyzed from the Vanderbilt
Pediatric Heart Institute using CPA. Cardiac assessment included global
longitudinal strain (GLS), global longitudinal strain rate (GLSR),
global circumferential strain (GCS), global circumferential strain rate
(GCSR). Mean strain values with standard deviation (SD) are reported.
The Wilcoxon rank sum test, linear regression and one-way analysis of
variance were used to assess differences among the various groups.
Results Among 142 children analyzed, 79 (56%) were male, and
the median age was 5.5 (range, 0-18) years. The mean (SD) strain values
were GLS -19.3 ± 3.4, GLSR -1.1 ± 0.22; GCS -24.7 ± 4.3, GCSR -1.5 ±
0.28. Age accounted for <8% of variation in GLS, GCS and
GSCR. However, for GLSR, there was a statistically significant
difference between younger and older age groups with higher GLSR in the
younger age group. Age accounted for ~25% of variation
in GLSR (R = 0.25, P < 0.001). There were
no significant differences in strain based on sex. Conclusion
We report normal reference values in healthy children by age for strain
using CPA. These values are necessary for the interpretation of 2D
strain imaging for both clinical care and research.
Efficacy of cervical pessary versus cervical cerclage in preventing spontaneous preterm birth: a meta-analysis
Authors: Liu Yana , zhiwei Xue , Zhou Shu
Published: April 2022

Backgroud: The clinical efficacy and safety of cervical pessary versus
cervical cerclage in preventing spontaneous preterm birth remain
uncertain. Objectives: To systematically review the clinical efficacy of
cervical pessary versus transvaginal cervical cerclage in preventing
spontaneous preterm birth caused by cervical shortening. Search
Strategy: The Cochrane Library, PubMed, EMbase, WanFang Data, CNKI, VIP
Data and CBM Data were electronically searched. Selection Criteria:
Randomized controlled trials (RCTs) and non-randomized controlled trials
(non-RCTs, including cohort studies) comparing cervical pessary and
transvaginal cervical cerclage in preventing spontaneous preterm birth
from the inception of the database to August 2020. Main Results: A total
of 9 studies (2 RCTs and 7 non-RCTs) were included, involving 1174
patients with a short cervix in the second trimester (cervical length
<25mm), 693 in the cervical pessary group and 481 in the
cervical cerclage group. The results of meta-analysis showed that the
incidence of preterm premature rupture of the membranes (PPROM) in the
cervical pessary group was significantly lower than that in the cervical
cerclage group (RR=0.48, 95% CI: 0.35 to 0.67, P<0.00001),
and the premature birth rate before 34 weeks in the cervical pessary
group was also significantly lower than that in the cervical cerclage
group (RR=0.68, 95%CI: 0.51 to 0.89, P<0.006). Conclusion:
Compared with transvaginal cervical cerclage, use of a cervical pessary
may decrease the risks of PPROM and premature birth before 34 weeks.
Given its advantages of easy-to-use and minimal damage, cervical pessary
may become a useful preventive intervention that deserves widespread
clinical application.
Metal Anti-wear Device Structure Optimization Design and Application in CFB Boiler
Authors: Wei Liping , Li Xin , Zhang Maozhen , Wu Feng , luo kun
Published: April 2022

Based on the principle of active anti-wear method, seven metal anti-wear
devices of types A through G were designed and numerically evaluated by
comparing the erosion distribution of the local water wall surface in
this work. The result shows: an approximate vertical triangle structure
with an inclined upper surface and a vertical lower surface, is the most
ideal structure for reducing the erosion rate. The type G and ash
deposition can be combined into this ideal structure. The simulation
results based on the type G show that the erosion rate increases
correspondingly with the increasing inlet velocity and particle size and
is somewhat mitigated by the addition of cohesive particles. The height
of the ash deposition zone decreases with decreasing particle diameter
and proportion of cohesive particles. The type G is preferred to be
tested on the CFB boiler for half a year, and achieved a good anti-wear
effect.
Loop electrosurgical excision in the treatment of precancerous lesions of the cervix
Authors: Djurdjevic Srdjan , Nisevic Jelena
Published: April 2022

Introduction. In the period from 2010 to 2021, 150 patients were treated with
loop electrosurgical excision of the cervix at the Special Gynecological
Hospital ?Genesis?, Novi Sad. The aim of this study was to present the
results of treatment, incidence of complications and recurrences after loop
excision in the treatment of cervical dysplasia. Material and Methods. The
study group A included 87 (58%) patients with cervical intraepithelial
neoplasia, and the control group B included 63 (42%) patients with benign
lesions of the cervix. Results. The total number of complications (bleeding,
pain, infection) in the group A was recorded in 16 (20.7%) and in group B in
4 (6.4%) patients, and this difference was statistically significant. The
absolute risk of complications in the group A was 18.39% and 6.34% in the
group B. The relative risk of complications was 2.9, meaning that women in
group A had a 3 times higher relative risk of complications compared to
women in the group B. The absolute risk of recurrence in the group A was
4.56% and 4.76% in the group B. The relative risk of recurrence was 0.96.
Women in the group A had a 4% lower relative risk of recurrence than women
in the group B. The recurrence rate was lower in the group B (4.8%) compared
to the group A (5.9%), but this difference was not statistically
significant. Conclusion. Loop electrosurgical excision is the treatment of
choice in the treatment of cervical dysplasia with good therapeutic outcomes
and a low complication and recurrence rate.
Appropriate use of the homeostasis model assessment of insulin resistance indices
Authors: Ivanov David , Zubnar Andrea , Tapavicki Borislav , Janjic Nebojsa , Karaba-Jakovljevic Dea , Naumovic Nada
Published: April 2022

Introduction. Timely detection of insulin resistance is of great importance
and a number of indices have been developed for its evaluation, among which
the homeostasis model assessment of insulin resistance index is the most
commonly used in clinical practice. However, it can be calculated via two
different models - homeostasis model assessment 1 and homeostasis model
assessment 2. Most studies determine the cut-off values of the study
population using the homeostasis model assessment 1, while recently most
physicians use homeostasis model assessment 2 in everyday clinical practice.
The aim of our study was to examine whether there was a difference in the
values of homeostasis model assessment of insulin resistance and homeostasis
model assessment of panceratic beta cells function calculated using these
two models. Material and Methods. Laboratory findings of 42 patients who
were diagnosed with glycemia and insulinemia were used in this study.
Fasting and postprandial glycemia and insulinemia were used to calculate
homeostasis model assessment indices using homeostasis model assessment 1
and homeostasis model assessment 2. Results. When comparing the values of
the homeostasis model assessment of insulin resistance and homeostasis model
assessment B indices, calculated via homeostasis model assessment 1 and
homeostasis model assessment 2, we found a statistically significant
difference (p < 0.001) which was also obtained when comparing the values of
the homeostasis model assessment B index. Linear correlation analysis showed
a significant positive correlation between the measured values of the
homeostasis model assessment of insulin resistance (calculated via both
models) and postprandial insulinemia at 120 minutes (p < 0.005). Conclusion.
The results indicate that homeostasis model assessment 2 yields
significantly lower homeostasis model assessment of insulin resistance and
homeostasis model assessment B index values than when calculated by the
homeostasis model assessment, which may be a stumbling block in the use of
homeostasis model assessment index. It is necessary to pay attention which
homeostasis model assessment model was used to define the cut-off values of
these indices, and to use the same model in the diagnosis of insulin
resistance in each patient in everyday clinical practice.
The importance of lip muscle activity in determining the position of the anterior teeth in deep bite
Authors: Radumilo Danijela , Vucinic Predrag , Ivic Stojan , Petrovic Djordje
Published: April 2022

Introduction. Low-strength forces of the soft tissues are closely related to
the stomatognathic system morphology. The muscles of the lips have a
significant influence on the position of the front teeth. The goals of our
research were to: 1. Examine the electromyographic activity of the circular
muscle of the lips in Class I and Class II division 2 patients with incisor
retrusion in the position of physiological rest and centric occlusion at
maximum voluntary muscle contraction; 2. Examine the existence of a
correlation between the electromyographic activity of the lip muscles and
the position of the incisors in the examined groups. Material and Methods.
The action potentials of the circular muscle of the lips were registered at
different positions of the lower jaw. Intramuscular coaxial electrodes were
placed according to the Greenfield scheme. Measurements were performed
bilaterally, summed up with ten muscle levels, in 100 patients aged 8 - 12
years; 30 patients were in the control group with neutroclusion, i.e. Class
I and 70 patients in the study group with Class II division 2, according to
Angle. Results. The results are given in microvolts as average cumulative
voltage of action potential amplitudes, which were used to determine changes
in the orbicular muscle activity. After statistical analysis of the obtained
data, it was concluded that the bioelectrical activity of the examined
muscles at all measured positions was lower in patients with distoclusion,
except for the lower lip in patients with Class II division 2, where this
activity was significantly higher. Conclusion. The results of the study show
that the determined changes in the action potentials of the circular muscles
of the lips in subjects with distoclusion indicate a cause-and-effect
relationship between muscle function and occlusion. A significantly
increased activity of the lower lip in deep bite can be considered
responsible for the steep position of the upper incisors.
High-temperature evolution of diamond-SiC composites
Authors: Bódis Eszter , Cora Ildikó , Fogarassy Zsolt , Veres Miklós , Németh Péter
Published: April 2022

Diamond-SiC composites are attractive for improving the catastrophic fracture
behaviour of SiC. However, fundamental knowledge is missing about the
structure of this system and the mechanism of diamond graphitization. We
used spark plasma sintering to study the diamond-Si-SiC system between 1600
and 2000?C in the function of nanocrystalline (ND) and microcrystalline
(MD) diamond addition as well as the quantity of Sibonding phase. Increasing
sintering temperature induces intense graphitization and formation of
nano-onions, few-layered graphene and well-ordered graphite in the prepared
composites at elevated temperature. High resolution transmission electron
microscopy study demonstrates the occurrence of the previously erroneously
identified 5H-SiC polytype in the samples prepared at 2000?C. Regardless of
Si and diamond contents, SiC formation is not confirmed even at high
temperature.
The effect of alkaline earth metal substitution on thermoelectric properties of A0.98La0.02MnO3-δ (A=Ca,Ba)
Authors: Singh Sathya , Kanas Nikola , Einarsrud Mari-Ann , Wiik Kjell
Published: April 2022

The thermoelectric properties of ceramics with composition A0.98La0.02MnO3-?
are anticipated to vary with the basicity and atomic portion of the alkaline
earth metal, A. In the present investigation ceramic powder precursors with
composition A0.98La0.02MnO3-? (A = Ca, Ba) were synthesized by the
solid-state method and sintered in air at 1400?C. Seebeck coefficient,
electrical and thermal conductivities were characterized for both materials
from 100 to 900?C in air. The highest zT of 0.10 at 900?C was reached for
Ca0.98La0.02MnO3-?. The high zT is attributed to the enhanced electronic
conductivity (?90 S/cm at 900?C) due to La doping. zT for
Ba0.98La0.02MnO3-? reached its highest value (0.02) at 800?C corresponding
to a low electronic conductivity (?2 S/cm), while the thermal conductivity
was significantly reduced compared to Ca0.98La0.02MnO3-? reaching ?1W/(m?K)
combined with a high Seebeck coefficient, ?290 ?V/K. The present data
represent a valuable basis for further development of these materials with
respect to applications in thermoelectric devices.
LANGUAGE STYLES OF IPHONE ADVERTISEMENT SLOGANS
Authors: Rozalina Rozalina
Published: April 2022

There were two research problems addressed in this research. The first was to classify and analyze lexical and syntactic features that were contained in iPhone advertisement slogans. The second was to find out what characterizes the uses of lexical and syntactic features in iPhone advertisement slogans. The data were taken from an online iPhone advertisement slogan from the second version to the latest iPhone version recently. This research used a document analysis method and was categorized as qualitative and quantitative research. After classifying and analyzing the data, the researcher calculated the frequency to identity the top three mostly employ in lexical and syntactic features used in iPhone advertisement slogans. The results of the research were there are seven lexical features and seven syntactic features employed in iPhone advertisement slogans and the most three top dominant lexical features are simple vocabulary with 38.4%, hyperbole 21.1%, and potency with 19.2%. The top three commonly used syntactic features are short sentences with 23.5%, present tense with 19.6%, and long noun phrases with 13.7%. Those language styles are used to grab the customers attention.
Artificial intelligence technologies in the field of road safety: problems and prospects
Authors: Kalyuzhny Yury Nikolaevich
Published: April 2022

The subject of the study is the norms of law and scientific sources characterizing the use of artificial intelligence technologies in the field of road safety. The object of the study is social relations that determine the basis for the use of artificial intelligence technologies in the field of road safety. As a result of studying normative legal acts, scientific literature, the author conducts a comprehensive analysis of the directions of the introduction and development of artificial intelligence technologies in the field of road safety, identifies individual scientific problems of legislative regulation of the sphere under consideration. The methodological basis of the study was a complex of general scientific and private scientific methods of cognition (formal legal, analytical, system method, analysis, synthesis, modeling, comparison, etc.). As a result, the author concludes that it is necessary to create comfortable organizational and legal conditions that allow, on the one hand, to ensure the further progressive introduction and development of artificial intelligence in the field of traffic and ensuring its safety, and on the other hand, to ensure the protection of the rights and legitimate interests of road users from possible threats to its use. The general conclusion of the author is the statement that the active development and introduction of artificial intelligence technologies in the field under consideration is the very tool that allows for the successful implementation of strategic objectives of socio-economic development of our country. The novelty of the research consists in a comprehensive analysis of theoretical legal and organizational aspects characterizing the use of artificial intelligence technologies in the field of road safety, identifying individual problems of legislative regulation and prospects for the implementation of strategic objectives of socio-economic development of our country in this area.
Balance of interests of the parties to labor relations in the introduction of digital technologies
Authors: Filyushchenko Lyudmila Ivanovna
Published: April 2022

The subject of the study is labor relations undergoing significant changes due to the digitalization of the economy and public life. The object of the study is the norms of labor legislation regulating the use of digital technologies in the field of labor relations, as well as the emerging practice of their application. The norms are analyzed from the point of view of ensuring a balance of rights and interests of the parties to labor relations. Attention is paid to the new rules for the introduction of electronic document management, the transition to accounting of information about work in electronic form, the implementation of remote work. General and private scientific research methods (formal legal, interpretation, comparison, mental modeling) were used. The main conclusion is the revealed imbalance of individual norms regulating the digital space in the field of labor relations. In some cases, the balance is violated in favor of employers, and the rights of employees are infringed. It was found ineffective to transfer the issue of providing labor means or payment of compensation for the use of their equipment to the discretion of social partners. It is proposed to legislate the provision of equipment and other means of labor by the employer if the initiative in remote work comes from him, as well as to limit the possibility of remote monitoring (supervision) of employees in the performance of their work duties. The use of electronic signatures requires a uniform approach that excludes the multiplicity of electronic signatures.
On the constitutionality of the ban on the use of the Internet by a suspect or accused
Authors: Bakradze Andrei Anatol'evich , Belov Dmitry Olegovich , Kalinin Aleksandr Nikolaevich
Published: April 2022

The article examines the theoretical and applied problems of the prohibition of the use of the information and telecommunications network "Internet" by a suspect or accused when choosing a preventive measure in the form of a ban on certain actions, bail or house arrest; analyzes, in connection with the fundamental rights and freedoms of man and citizen, the changes introduced by Federal Law No. 72-FZ of 18.04.2018 changes in The Criminal Procedure Code of the Russian Federation; thematic judicial practice is given; legal solutions aimed at optimizing the current legislation and the practice of its application are proposed, while legal issues are correlated with the role of the Internet in modern society and human life. According to the results of the study, the authors come to the conclusion that the legal stereotypes that have existed for a long time about the inseparable connection of the restriction of the constitutional right to freedom when placed under house arrest with other restrictions of constitutional rights, although not explicitly specified in the law, are actually applied to a suspect or accused under house arrest. Among such restrictions, we will find, for example, a ban on performing labor (official) duties, searching for and receiving information, various types of creative activity (literature, painting, science, technology, etc.). These restrictions could have been formed only in a "pre-digital" society and therefore require revision.
The Invention of the Coin, Mentoring Literature and Philosophy: the Economism of Axial Time and the Social Problems of Antiquity
Authors: Khaustov Dmitry Sergeevich
Published: April 2022

The subject of the study is the relationship between the parallel development of the processes of the invention of the antique coin, mentoring literature and the formation of the worldview of Axial time. The object of the research are review works devoted to various aspects of the social problems of the ancient era: the relationship of coin making and military affairs, the relationship of world religions and mentoring literature, the economism of urbanisation of the polis type and the genesis of classical philosophy. The relevance of the research is determined by the fact that the realities that appeared in the era of interest to us: world religions, coin money and mentoring literature – still exist. The secret of the duration of their existence is an urgent problem for social philosophy and historical sociology. The purpose of the study is to consider the possible reasons for the social dynamics recorded in the history of Eurasia, which Karl Jaspers called "Axial Time", but in conjunction with the development of monetary systems and mentoring preaching. In the study of the research problem, general scientific methods were used: analysis, synthesis, comparison. As a research method, the classical (qualitative) analysis of the document was taken as a basis. The comparative analysis revealed a certain connection between the above–mentioned phenomena and the growth of social problems of the ancient civilization - a polis-type civilization against the background of the aggravation of the contradictions of urbanization. The result of the study was the hypothesis of the creation of coin money as a tool to reduce the level of violence within ancient societies. Money in the form of coins became a kind of form of social protection of ancient communities, although it was originally intended to finance organized violence. The practical significance of the study is to form the basis for practical recommendations on adapting the conclusions of the article for the purposes of social policy of modern states.
Potential threats to the use of genetic technologies and legal ways to resolve them
Authors: Karimov Vyacheslav Khamitovich , Kazantsev Dmitrii Aleksandrovich
Published: April 2022

The object of the study is public relations in the field of the use of genetic technologies and their impact on human and civil rights and freedoms, ensuring the security of society and the state. The subject of the study is the provisions of international law, the legislation of the Russian Federation in the field under consideration, the norms of Russian and international law in the field of criminal law protection of relations that may be jeopardized by the use of genomic technologies. The authors draw attention to the fact that the existing legal system does not fully solve the tasks of ensuring the security of human and civil rights and freedoms, society, the state, environmental protection from dangerous encroachments using advances in the field of genetics. The results of the study are based on formal logical and general scientific methods of scientific cognition, a systematic approach. In addition, private scientific methods: formal legal, comparative legal method of legal interpretation. The main conclusions of the study are the following provisions. Potential threats that pose a danger to human life and health, ensuring the safety of society and the environment have been identified. Potential risks may arise in the field of human genetic research, genome editing technologies of various organisms, illegal collection and use of genetic information about a person, the threat of the development and use of genetic weapons as a type of biological weapon, in the field of regulating the activities of DNA laboratories, the use of genetic material for cloning and the use of human embryonic material. As a solution, it is proposed to use the positive foreign experience indicated in the work, the ideas of domestic authors and also the author's proposals for improving the legal regulation of the sphere in question. The novelty of the study lies in the fact that actual and potential risks are identified that pose a serious danger not only to individuals, but also to society as a whole. Legal solutions for their elimination are proposed.