bluuebunny/crossref_metadata_2025 huggingface dataset:
Prostate volume index and prostatic chronic inflammation have an effect on tumor load at baseline random biopsies in patients with normal DRE and PSA values less than 10 ng/ml: results of 564 consecutive cases
Authors: Porcaro Antonio B. , Tafuri Alessandro , Sebben Marco , Shakir Aliasger , Novella Giovanni , Pirozzi Marco , Processali Tania , Rizzetto Riccardo , Amigoni Nelia , Tiso Leone , Cerrato Clara , Brunelli Matteo , Cerruto Maria Angela , Migliorini Filippo , Siracusano Salvatore , Artibani Walter
Published: August 2019

Background:

To assess the association of prostate volume index (PVI), defined as the ratio of the central transition zone volume (CTZV) to the peripheral zone volume (PZV), and prostatic chronic inflammation (PCI) as predictors of prostate cancer (PCA) load in patients presenting with normal digital rectal exam (DRE) and prostate-specific antigen (PSA) ⩽ 10 ng/ml at baseline random biopsies.

Methods:

Parameters evaluated included age, PSA, total prostate volume (TPV), PSA density (PSAD), PVI and PCI. All patients underwent 14 core transperineal randomized biopsies. We considered small and high PCA load patients with no more than three (limited tumor load) and greater than three (extensive tumor load) positive biopsy cores, respectively. The association of factors with the risk of PCA was evaluated by logistic regression analysis, utilizing different multivariate models.

Results:

564 Caucasian patients were included. PCA and PCI were detected in 242 (42.9%) and 129 (22.9%) cases, respectively. On multivariate analysis, PVI and PCI were independent predictors of the risk of detecting limited or extensive tumor load. The risk of detecting extensive tumor load at baseline biopsies was increased by PSAD above the median and third quartile as well as PVI ⩽ 1 [odds ratio (OR)=1.971] but decreased by PCI (OR=0.185; 95% CI: 0.088–0.388).

Conclusions:

Higher PVI and the presence of PCI predicted decreased PCA risk in patients presenting with normal DRE, and a PSA ⩽ 10 ng/ml at baseline random biopsy. In this subset of patients, a PVI ⩽ or >1 is able to differentiate patients with PCA or PCI.
Possibility of Local Allergic Rhinitis in Japan
Authors: Ishida Mariko , Matsune Shoji , Wakayama Nozomu , Ohashi Ryuji , Okubo Kimihiro
Published: August 2019

Background

The concept of local allergic rhinitis (LAR) has been advocated recently. Allergic rhinitis in Japan is characterized by house dust mites (HDMs) and Japanese cedar pollen (JCP). To investigate LAR in Japan, total IgE and antigen-specific IgE (sIgE) were measured in inferior turbinate mucosa and their relationships with skin test (ST) and nasal allergen provocation test (NAPT) and as well as serum IgE levels were examined.

Methods

Subjects were 50 rhinosinusitis patients for surgery. ST was performed and serum total IgE and sIgE levels were measured preoperatively. Patients with class-0 serum anti-HDM or anti-JCP sIgE levels were subjected to NAPT with HDM or JCP, respectively, or both. In all patients, inferior turbinate mucosa was weighed and mashed, and total IgE and sIgE levels were then measured as local mucosal date per gram and per milligram. Because there is no clinical consensus how to evaluate nasal sIgE yet, both positive NAPT and detectable sIgE in obtained nasal mucosa were adopted as the diagnostic criteria of LAR in order to strictly elucidate the possibility of presence of LAR in Japan.

Results

JCP LAR was definitely diagnosed in 2 of 14 patients (14.3%) and HDM LAR in 5 of 21 (23.8%) in cases with rhinosinusitis symptoms in the absence of positive ST nor serum sIgE.

Conclusion

The present results positively support LAR by HDM or JCP being present in Japan.
Ameloblastic fibro-odontoma associated with paresthesia of the chin and lower lip in a 12-year-old girl
Authors: Saeed Dereen Mohammed , Setty Suman , Markiewicz Michael R , Cabay Robert J
Published: August 2019

Ameloblastic fibro-odontoma is a rare, benign, and slowly growing neoplasm of the jaw composed of proliferating odontogenic epithelium in ectomesenchymal tissue along with dental hard tissue formation. Herein, we describe a case of an ameloblastic fibro-odontoma in 12-year-old female with paresthesia of the chin and lower lip. Panoramic radiography showed a radio-opacity in the right posterior mandible near the mandibular canal and associated with the right mandibular third molar. Histologically, the lesion contained epithelial and mesenchymal odontogenic components in close proximity to odontoma-like elements. Enucleation and curettage of the affected site in the mandible resulted in resolution of the paresthesia postoperatively.
Do Industrial Clusters Still Matter to Trust-Building in the Internet Era? A Network Embeddedness Perspective
Authors: Wei Wanyue , He Zheng , Rayman-Bacchus Lez , Xiang GuangMing
Published: August 2019

Despite the considerable amount of research regarding trust as one of the most important characters and competitive advantages for an industrial cluster, few empirical studies have examined whether geographic proximity still leads to higher levels of trust in the current Internet era. This article explores this issue of trust from a network embeddedness perspective. Based on the data from Zhongshan gas appliance cluster, we employ structural equation modeling to examine the extent to which relational embeddedness, structural embeddedness, and positional embeddedness have any impact on trust-building in the cluster. Our findings reveal that high clique trust and low aggregate trust coexist in the cluster, showing that the effect of geographical proximity on trust has been weakened and is no longer a sufficient condition for trust-building. This study also gives some suggestions on how to improve the trust within a cluster through network governance.
Legitimacy Struggles in Global Governance: Legitimation and Delegitimation of the Asian Infrastructure Investment Bank
Authors: Uhlin Anders
Published: August 2019

The Chinese-led Asian Infrastructure Investment Bank (AIIB) started operation in January 2016 in the context of severe criticism from the U.S. government and transnational civil society organizations, but with the support from major Asian and European states. The establishment of this new global governance institution (GGI) raises intriguing questions concerning legitimacy and (de)legitimation. What legitimacy challenges has the AIIB as a new institution experienced and how has the Bank tried to boost its legitimacy? What specific legitimation and delegitimation practices have been applied by what actors and with what effects? Contributing to research on legitimacy in global governance, this article develops a framework for analyzing legitimacy struggles. It highlights the dynamic relations between legitimation (practices intended to boost beliefs that the rule of a political institution is exercised appropriately) and delegitimation (practices challenging the appropriateness of a political institution’s exercise of authority). The framework includes a systematic study of different agents of (de)legitimation (including GGIs, states, and nonstate actors), practices of (de)legitimation (categorized as institutional and discursive), and institutional sources of (de)legitimation (related to procedure as well as performance). The case study, based on in-depth qualitative content analysis of documents produced by the AIIB and other actors, demonstrates how legitimizers and delegitimizers respond to each other. Being a new GGI, legitimacy struggles on the AIIB have to a large extent focused on its institutional design referring to (the lack of) democratic procedures. Legitimizers tend to stress technocratic performance, whereas delegitimizers are more concerned with fair performance.
SIR-Spheres® Y-90 resin microspheres in chemotherapy refractory or intolerant patients with metastatic colorectal cancer
Authors: Coretti Silvia , Rumi Filippo , Sacchini Dario , Cicchetti Americo
Published: August 2019

Selective internal radiation therapy is a form of intra-arterial brachytherapy used to treat primary liver cancer and liver metastases. This article aims to provide an overview of the clinical, economic, organizational legal, social and ethical impact of selective internal radiation therapy using SIR-Spheres Y-90 resin microspheres in the treatment of patients with unresectable, liver-dominant metastatic colorectal cancer who are refractory to or intolerant of chemotherapy. A systematic literature review was performed by querying PubMed, Scopus, EBSCO, CRD and GIN. Two reviewers blindly screened the records retrieved against predefined inclusion/exclusion criteria. The selected studies where summarized following a simplified version of the EuNetHTA Core Model® 2.1. The studies included evaluated selective internal radiation therapy in first-line or further-line treatment and showed a good safety and tolerability profile and significant improvement in efficacy expressed as time to liver progression, progression-free survival and overall survival. Selective internal radiation therapy should be provided in specialized centres and administered by a multidisciplinary team. A hub-and-spoke network could be a viable option to guarantee access to this technology across jurisdictions. The lack of a specific diagnosis-related group tariff accounting for the cost of the device could be seen as the major obstacle to a fair diffusion of this technology. The economic evaluations currently available show the cost-effectiveness of this technology in the population under study. Selective internal radiation therapy using SIR-Spheres Y-90 resin microspheres appears to be a clinically effective and cost-effective option in the treatment of metastatic colorectal cancer patients who are chemotherapy refractory or chemotherapy intolerant.
Full Recovery From Cocaine-Induced Toxic Leukoencephalopathy: Emphasizing the Role of Neuroinflammation and Brain Edema
Authors: Mader Edward C. , Ramos Alexander B. , Cruz Roberto A. , Branch Lionel A.
Published: August 2019

Toxic leukoencephalopathy (TL) is characterized by white matter disease on magnetic resonance imaging (MRI) and evidence of exposure to a neurotoxic agent. We describe a case of cocaine-induced TL in which extensive white matter disease did not preclude full recovery. A 57-year-old man with substance abuse disorder presented with a 5-day history of strange behavior. On admission, he was alert but had difficulty concentrating, psychomotor retardation, and diffuse hyperreflexia. Brain MRI revealed confluent subcortical white matter hyperintensities with restricted diffusion in some but not in other areas. Electroencephalography (EEG) showed mild diffuse slowing. Blood tests were normal except for mild hyperammonemia. Urine screen was positive for cocaine and benzodiazepine but quantitative analysis was significant only for cocaine. Prednisone 60-mg qd was initiated on day 4, tapered over a 5-day period, and discontinued on day 9. He was discharged after 3 weeks. Cognitive function returned to normal 2 weeks after discharge. Five months later, neurologic exam and EEG were normal and MRI showed near-100% resolution of white matter lesions. TL has been attributed to white matter ischemia/hypoxia resulting in demyelination/axonal injury. The clinical, EEG, and MRI findings and time course of recovery of our patient suggest that cocaine-induced inflammation/edema resulted in TL but not in ischemic/hypoxic injury. While inflammation/edema may have regressed when cocaine was discontinued, we cannot exclude a role for prednisone in protecting the patient from the ischemic/hypoxic sequelae of inflammation/edema. MRI is indispensable for diagnosing TL but EEG may provide additional useful diagnostic and prognostic information.
Revision Ulnar Collateral Ligament Reconstruction in Professional Baseball: Current Trends, Surgical Techniques, and Outcomes
Authors: Camp Christopher L. , Desai Vishal , Conte Stan , Ahmad Christopher S. , Ciccotti Michael , Dines Joshua S. , Altchek David W. , D’Angelo John , Griffith Timothy B.
Published: August 2019

Background:

Ulnar collateral ligament (UCL) reconstruction of the elbow is commonly performed on professional baseball pitchers. Recent reports have suggested that revision rates are on the rise and may be higher than previously thought.

Purpose:

To provide a comprehensive report on current trends, surgical techniques, and outcomes of revision UCL reconstructions performed on professional baseball pitchers between 2010 and 2016.

Study Design:

Case series; Level of evidence, 4.

Methods:

The Major League Baseball Health and Injury Tracking System (HITS) was used to compile records of all revision UCL reconstructions performed on professional baseball pitchers between 2010 and 2016. Player data and outcomes were obtained from HITS, and surgical details were obtained from operative reports. Descriptive statistical analysis was performed on epidemiologic data. Outcomes (return to play [RTP] rates, RTP times, subsequent injuries, and subsequent surgeries) were compared across the most common surgical techniques (docking vs modified Jobe) and graft sources (palmaris longus autograft vs hamstring autograft).

Results:

A total of 69 professional baseball pitchers underwent revision UCL reconstruction from 2010 to 2016 at an average of 1424 days (47 months) after their primary surgery. A trend was seen toward increasing numbers of revision surgeries over time ( R2 = 0.441; P = .104). The most commonly used tunnel configuration was the modified Jobe technique (n = 41; 59.4%), and the most commonly used graft was hamstring autograft (n = 34; 49.3%). A majority (76.6%) of pitchers achieved RTP, and 55.3% were able to return to the same level of play. Mean time to RTP was 436 days (14.5 months) for players with a palmaris longus autograft versus 540 days (18 months) for those with a hamstring autograft ( P = .108). Further, the mean time to RTP was 423 days (14 months) for the docking technique versus 519 days (17 months) for the modified Jobe technique ( P = .296). Similar rates of subsequent injuries and surgeries were noted between the 2 revision techniques and 2 most commonly used graft constructs.

Conclusion:

Revision UCL reconstruction showed relatively high RTP rates (77%), but only 55% of players returned to their same level of play. Mean time to RTP was shorter than that found in other, smaller investigations. Although general trends were seen toward decreased time to RTP for the docking technique and palmaris longus autograft, these differences did not reach statistical significance.
Health Utility Book (HUB)–Cancer: Protocol for a Systematic Literature Review of Health State Utility Values in Cancer
Authors: Zoratti Michael James , Zhou Ting , Chan Kelvin , Levine Oren , Krahn Murray , Husereau Don , Clifford Tammy , Schunemann Holger , Guyatt Gordon , Xie Feng
Published: August 2019

Background. Treatment options in oncology are rapidly advancing, and public payer systems are increasingly under pressure to adopt new but expensive cancer treatments. Cost-utility analyses (CUAs) are used to estimate the relative costs and effects of competing interventions, where health outcomes are measured using quality-adjusted life years (QALYs). Health state utility values (HSUVs) are used to reflect health-related quality of life or health status in the calculation of QALYs. To support reimbursement agencies in the appraisal of oncology drug submissions, which typically include a CUA component, we have proposed a systematic literature review of published HSUV estimates in the field of oncology. Methods. The following databases will be searched: MEDLINE, EMBASE, EconLit, and CINAHL. A team of reviewers, working independently and in duplicate, will evaluate abstracts and full-text publications for eligibility against broad inclusion criteria. Studies using a direct, indirect, or combination approach to eliciting preferences related to cancer or cancer treatments are eligible. Data extraction will capture details of study methodology, participants, health states, and corresponding HSUVs. We will summarize our findings with descriptive analyses at this stage. A pilot review in thyroid cancer is presented to illustrate the proposed methods. Discussion. This systematic review will generate a comprehensive summary of the oncology HSUV literature. As a component of the Health Utility Book (HUB) project, we anticipate that this work will assist both health economic modelers as well as critical reviewers in the development and appraisal of CUAs in oncology.
Educational Impact of a Podcast Covering Vitreoretinal Topics: 1-Year Survey Results
Authors: Venincasa Michael J. , Cai Louis Z. , Chang Angela , Kuriyan Ajay E. , Sridhar Jayanth
Published: August 2019

Purpose:

This article aims to determine preferences and demographics for listeners of an ophthalmology podcast, since podcasts are gaining favor for medical education.

Methods:

The present study used a cross-sectional, online survey as well as Podtrac, Inc and Squarespace, Inc platform analytics to examine perceived educational usefulness of podcasts for listeners.

Results:

Quarterly episode downloads increased from 684 in first-quarter 2017 to 16 016 in third-quarter 2018. A total of 102 participants completed the survey: 82 (80.4%) men and 68 (66.7%) retina attending physicians or fellows. Most respondents listened to “stay up to date” or “learn more about the field of retina” (67; 65.7% each). Most respondents agreed that podcasts are useful for medical education and result in changes in practice, but not that podcasts have surpassed traditional educational methods. For respondents, there was no difference in perceived usefulness between podcasts and peer-reviewed journals, textbooks, continuing medical education lectures, or national conferences; these did not differ with respondent listening histories.

Conclusions:

Podcasts are valuable adjuncts for distributing clinically relevant material.
An Investigation of the Music Literature Being Performed at Jazz Band Music Performance Assessments in Florida
Authors: Warnet Victoria
Published: August 2019

The purpose of this study was to examine the performance trends of middle school, junior/senior high school, and high school ensembles at District Florida Bandmasters Association (FBA) Jazz Band Music Performance Assessments (MPAs) from 2012 to 2017. More specifically, this study investigated the pieces, composers, and arrangers most frequently performed, and how many schools participated. Data were derived from a pool of compositions performed at FBA District Jazz Band MPAs between 2012 and 2017 ( N = 5,664). Of the pieces performed, there were 1,816 different compositions played. The compositions performed featured 619 different composers and 249 different arrangers. Additionally, 47.78% of schools involved in FBA had at least one jazz band perform during the 5-year period analyzed in this study. Overall, findings suggested that secondary school jazz bands in Florida have grown in popularity.
Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas
Authors: Kvikstad Vebjørn , Mangrud Ok Målfrid , Gudlaugsson Einar , Dalen Ingvild , Espeland Hans , Baak Jan P. A. , Janssen Emiel A. M.
Published: August 2019

Background

European treatment guidelines for pTa and pT1 urinary bladder urothelial carcinoma depend highly on stage and WHO-grade. Both the WHO73 and the WHO04 grading systems show some intra- and interobserver variability. The current pilot study investigates which histopathological features are especially sensitive for this undesired lack of reproducibility and the influence on prognostic value.

Methods

Thirty-eight cases of primary non-muscle invasive urothelial carcinomas, including thirteen cases with stage progression, were reviewed by three pathologists. Thirteen microscopic features were extracted from pathology textbooks and evaluated separately. Reproducibility was measured using Gwet’s agreement coefficients. Prognostic ability regarding progression was estimated by the area under curve (AUC) of the receiver operating characteristics (ROC) function.

Results

The best reproducible features (Gwet’s agreement coefficient above 0.60) were papillary architecture, nuclear polarity, cellular maturation, nuclear enlargement and giant nuclei. Nucleoli was the strongest prognostic feature, and the only feature with an AUC above 0.70 for both grading systems, but reproducibility was not among the strongest. Nuclear polarity also had prognostic value with an AUC of 0.70 and 0.67 for the WHO73 and WHO04, respectively. The other features did not have significant prognostic value.

Conclusions

The reproducibility of the histopathological features of the different WHO grading systems varied considerably. Of all the features evaluated, only nuclear polarity was both prognostic and significantly reproducible. Further validation studies are needed on these features to improve grading of urothelial carcinomas.
Full-angle extended elastic impedance
Authors: Sharifi Javad , Mirzakhanian Marzieh
Published: August 2019

Application of seismic interpretation for fluid detection in carbonate reservoirs has been a major challenge for researchers in the past few decades. In this context, many approaches have been introduced, but they failed to be effective enough in the presence of different pore types in carbonate rocks. On this basis, we have developed a novel method called full-angle extended elastic impedance (FEEI) analysis as an alternative to seismic interpretation for fluid detection. Investigating the entire trend of changes in extended elastic impedance (EEI) values with [Formula: see text] angles (the intercept-gradient coordinate rotation angles), FEEI analysis can efficiently discriminate fluid types in carbonate reservoirs. The first steps in the application of the proposed method include performing fluid substitution modeling and making FEEI templates using FEEI analysis for different saturation scenarios. Subsequently, the derived FEEI method was subjected to validation and verification based on a carbonate case study with five existing wells drilled into a zone containing oil and brine. Next, we inverted the prestack seismic data to EEI data at corresponding [Formula: see text] angles, followed by interpreting the resultant EEI data by FEEI templates. Comparisons between the obtained EEI-inverted sections indicated the robustness and reliability of the proposed approach in estimating the type of pore fluid in the selected carbonate interval. Finally, estimation results were successfully tested on a blind well, which ended up with promising results, and we discuss the uncertainties associated with this methodology. The findings of this research include the introduction of a novel EEI template (i.e., FEEI template) and two new rock-physics templates for fluid detection, with the considered case study confirming the applicability of the proposed FEEI in a carbonate field.
Predictors of therapeutic treatment outcome in adolescent chronic tic disorders
Authors: Nissen J. B. , Parner E. T. , Thomsen P. H.
Published: August 2019

Background

Chronic tic disorders may have a major impact on a child's function. A significant effect has been shown for combined habit reversal training (HRT) and exposure response prevention (ERP) treatment delivered in an individual and group setting.

Aims

The present study examines predictors and moderators of treatment outcome after an acute therapeutic intervention.

Method

Fifty-nine children and adolescents were randomised to manualised treatment combining HRT and ERP as individual or group training. Age, gender, baseline tic severity, Premonitory Urge for Tics Scale (PUTS) scores, Beliefs about Tic Scale (BATS) scores, hypersensitivity and comorbid psychiatric symptoms were analysed as predictors of outcome. The same characteristics were examined as moderators for individual versus group treatment. Outcome measures included the change in total tic severity (TTS) score and functional impairment score (as measured by the Yale Global Tic Severity Scale (YGTSS)).

Results

Internalising symptoms predicted a lesser decrease in functional impairment. The occurrence of obsessive–compulsive symptoms predicted a larger decrease in TTS. Baseline hypersensitivity and high scores on depressive symptoms favoured individual treatment. High baseline PUTS scores favoured group therapy.

Conclusions

This is the first study examining factors predicting and moderating perceived functional impairment following a therapeutic intervention. The study adds to the knowledge on predictors and moderators of TTS. Furthermore, this is the first study examining the effect of the BATS score. The study points towards factors that may influence treatment outcome and that require consideration when choosing supplemental treatment. This applies to comorbid anxiety and depressive symptoms, and to the child's belief about their tics and premonitory urge.

Declaration of interest

None.
Distinct actin cytoskeleton behaviour in primary and immortalised T-cells
Authors: Colin-York Huw , Kumari Sudha , Barbieri Liliana , Cords Lena , Fritzsche Marco
Published: August 2019

Cytoskeletal actin dynamics are crucial for the activation of T-cells. Immortalised Jurkat T-cells have been the model system of choice to examine and correlate the dynamics of the actin cytoskeleton and the immunological synapse leading to T-cell activation. However, it has remained unclear whether immortalised cellular systems, such as Jurkat T-cells can recapitulate the cytoskeletal behaviour of primary T-cells. Studies delineating the cytoskeletal behaviour of Jurkat T-cells in comparison to primary T-cells are lacking. Here, we employ live-cell super-resolution microscopy to investigate the cytoskeletal actin organisation and dynamics of living primary and immortalised Jurkat T-cells at the appropriate spatiotemporal resolution. Under comparable activation conditions, we found differences in the architectural organisation and dynamics of Jurkat and primary mouse and human T-cells. Although the three main actin network architectures in Jurkat T-cells were reminiscent of primary T-cells, there were differences in the organisation and molecular mechanisms underlying these networks. Our results highlight mechanistic distinctions in the T-cell model system most utilised to study cytoskeletal actin dynamics.
Timing manipulations reveal the lack of a causal link across timing of annual-cycle stages in a long-distance migrant
Authors: Tomotani Barbara M. , de la Hera Iván , Lange Cynthia Y. M. J. G. , van Lith Bart , Meddle Simone L. , Both Christiaan , Visser Marcel E.
Published: August 2019

Organisms need to time their annual-cycle stages, like breeding and migration, to occur at the right time of the year. Climate change has shifted the timing of annual-cycle stages at different rates, thereby tightening or lifting time constraints of these annual-cycle stages, a rarely studied consequence of climate change. The degree to which these constraints are affected by climate change depends on whether consecutive stages are causally linked (I) or whether the timing of each stage is independent of other stages (II). Under (I), a change in timing in one stage has knock-on timing effects on subsequent stages, whereas under (II) a shift in the timing of one stage affects the degree of overlap with previous and subsequent stages. For testing this we combined field manipulations, captivity measurements and geolocation data. We advanced and delayed hatching dates in pied flycatchers (Ficedula hypoleuca) and measured how the timing of subsequent stages (male moult and migration) were affected. There was no causal effect of manipulated hatching dates on the onset of moult and departure to Africa. Thus, advancing hatching dates reduced the male moult-breeding overlap with no effect on the moult-migration interval. Interestingly, the wintering location of delayed males was more westwards, suggesting that delaying the termination of breeding carries-over to winter location. Because we found no causal linkage of the timing of annual-cycle stages, climate change can shift these stages at different rates, with the risk that the time available for some become so short that this will have major fitness consequences.
Peak expiratory flow rate and chronic respiratory symptoms among restaurant workers: a cross-sectional study from Thailand
Authors: Juntarawijit Chudchawal
Published: August 2019

Background: Cooking smoke is a major source of indoor air pollution affecting millions of people worldwide. To date, there has been no epidemiological study to show the variation in health effects resulting from work at different kinds of restaurants in Thailand. This study determines lung function and chronic respiratory symptoms of workers in four types of eateries commonly found in Thailand.

Methods: This is a cross-sectional study of 321 people working in four common types of restaurants in Thailand: ‘tamsang’ restaurants (from the Thai word ร้านอาหารตามสั่ง, a restaurant that makes a variety of foods to order) (170 people), papaya salad restaurants (51 people), noodle restaurants (50 people), and barbecue stalls (50 people).  The restaurant workers’ demographic data as well as information on their working conditions was collected using a questionnaire administered in a face to face interview. Each worker’s peak expiratory flow rate was measured using a portable peak flow meter.

Results: This study found that working in a ‘tamsang’ restaurant is associated with a higher risk of poor lung function (OR = 2.59, 95% CI 1.33–5.06) and a higher prevalence of moderate dyspnea symptoms (OR = 3.79, 95% CI 1.63–8.79) compared to working in a papaya salad restaurant. The study also found that each of the following were associated with poor lung function and/or chronic respiratory symptoms: cooking with palm oil, having irritated teary eyes while cooking, cooking without a ventilation hood, long past experience working at restaurants, and working in a small cooking area (1–6 m2).

Conclusions: Work in different kinds of restaurants with variations in cooking methods and work conditions produces diverse effects on airway and lung function. Regulatory organizations should pay careful attention to protecting the health of restaurant workers, especially those working in ‘tamsang’ restaurants.
Energy Consumer Theory in the System of Scientific Knowledge
Authors: Бурганов Раис , Burganov Rais , Бурганова Зульфия , Burganova Zul'fiya
Published: August 2019

Article is devoted to the consideration of the theoretical and methodological foundations of the energy-consumer theory of a company, the creation of which is required by the need to take into account current trends in the consumption of various types and forms of energy in the production process and the provision of services. According to the author, the creation of a new theory of the company will allow to develop an effective energy market strategy of the company and more fully characterize the behavior of the company in the process of energy consumption in the innovative and digital economy. The article also describes the scientific elements of the theory; the process of energy consumption movement during the production of goods and services and consumption is defined for the study; the scientific principles of the firm’s energy-consumption theory and the elements of the mechanism for implementing the theory in practice are highlighted. Financial and economic indicators of the company should be improved taking into account the consumption of different forms and types of energy.
The Impact of Labor Remuneration and the Differentiation of Household Income on Labor Productivity in the Regions of Russia
Authors: Басовская Елена , Basovskaya Elena , Басовский Леонид , Basovskiy Leonid
Published: August 2019

The models of regions, econometric based on crosscutting statistics, have established that wages and the differentiation of household incomes have a significant impact on labor productivity in the regions of modern Russia. Changes in the level of remuneration and differentiation of incomes of the population in recent years explain 78–82% of changes in labor productivity in the regions, and the effect of the level of remuneration is twice the impact of the differentiation of incomes of the population. The impact of wages on productivity in the period grows. This indicates an increase in the efficiency of labor as a production factor. The influence of income differentiation on labor productivity, which had previously been lost due to the formation of an unfavorable institutional environment under the laws adopted in the country, resumed. The impact of income differentiation decreases, which indicates a decrease in its stimulating effect on labor productivity.
Unemployment in the Conditions of Digitization of the Regional Economy
Authors: Гриднева Б. , Gridneva B.
Published: August 2019

Modern trends in the digitalization of the national economy are rapidly moving from the service sector to manufacturing and further to simpler enterprises in terms of technology. The introduction of information and communication technologies leads to significant changes in the labor market. Some professions are in increasing demand, while others are almost dying out, replaced by new ones. Many jobs, according to analysts, will be lost in the process of digitalization, and disappeared jobs are not always replaced by new ones. Tyumen region is a pilot region included in the national project “Digital economy”. In addition, the city of Tyumen is a pilot site of the program of the Ministry of construction of the Russian Federation “Smart city”. The article analyzes the statistical indicators characterizing the current trends of unemployment in the regional labor market of the Tyumen region.
The Impact of Instructional Technology and Material Design Course on Pre-service Teachers
Authors: Calik-Uzun Selcen , Kul Umit , Celik Sedef
Published: August 2019

The purpose of this study is to evaluate the effects of Instructional Technologies and Material Design (ITMD) course on pre-service mathematics teachers’ attitudes, efficacy beliefs about using concrete materials, and their opinions regarding the material preparation process. A total of 73 pre-service teachers were participated in this study. The scale developed by Bakkaloglu was used to determine efficacy beliefs of pre-service teachers about using concrete materials, and the attitudes scale developed by Cetin, Bagceci, Kinay and Simsek was used to determine the attitudes towards ITMD course. A written form was also used to reveal the opinions of pre-service teachers regarding the material preparation process. The qualitative data collected from 16 pre-service teachers was analyzed with the MAXQDA. Using content analysis, codes and themes were created separately by the researchers and analyzed through several iterations. As a result of this study, positive changes were found in the attitudes and efficacy beliefs of pre-service teachers. The results obtained from the opinions of the pre-service teachers support this positive change. In other words, it is possible to argue that the attitudes of pre-service teachers towards the material development process changed positively with the positive change in the efficacy beliefs about preparing materials after taking the ITMD course.
Relationship between adenoid hypertrophy and sleep apnea in children
Authors: De lira Ana de Lourdes Sá , Silva Lucas Paulo Sousa
Published: August 2019

It was decided to organize this work on the assumption that it is necessary for all dental surgeons to familiarize themselves with the structure and alterations in oral anatomy from childhood, with attention to the possibility of adenoid hypertrophy (AH) and obstructive sleep apnea syndrome (OSAS) to be present, and these professionals can assist in orthodontic treatment. The objective of this literature review was to observe if there is a correlation between adenotonsillar hypertrophy and sleep apnea in children and which treatment were adopted. The following databases were searched: LILACS, MEDLINE, PubMed, Cochrane, Web of Science and SciELO, from January 2014 to August 2018. It is concluded that there is a correlation between hypertrophy of the adenoid glands and apnea of the sleep in children. Hypertrophy presents as the main cause of obstructive sleep apnea syndrome in pediatric patients and its treatment may be surgical, removal of the adenoid, drug or orthodontic glands.
The comparison of the rate of apical displacement in curved root canals using Neoniti and RaCe files by cone beam CT Scan
Authors: Godiny Mostafa , Nikkerdar Nafiseh , Hatam Reza , Shahsavand Leila , Khavid Atefeh
Published: August 2019

Background and aim: There is a high prevalence of root canal transportation in the teeth with the curve. effect of root canal transportation on the success of root canal therapy of tooth is negative and there is no study about comparing RaCe and Neoniti files in root canal transportation. The aim of this study is assessment and comparing two different RaCe and Neoniti files to determine transportation error in various parts of root using CBCT assessment and comparing them with each other.Method: In this experimental study 50 extracted mandibular molar teeth selected. Teeth were divided randomly into two groups i.e. 25 teeth threated with RaCe file (first group) and 25 teeth threated with Neonitu files (second group). in this study to measurement  thickness of dentine in the scan ,before and after instrumentation at the same time we used axial images that obtain from NNT viewer 6.1.0 software .Findings: in the first group ,The mean tooth transportation  in 5 mm of apex  was 0.15 and  in the second group The mean tooth transportation  in 5 mm of apex  was 0.18 mm that there was no statistically significant difference in canal transportation  between RaCe and Neoniti files in five millimeters distant from apex area (p=0.492) and the mean transportation from 9 mm of apex was 0.14 in the second group that There was no statistically significant difference in canal transportation between two  groups (p=0.911).Conclusion: The results indicated that there was no significant difference of tooth transportation between two file systems in 3, 9, 7, 5 and 11mm from the apex and both files were safe.
Krisis und Kritik. Zum Sprachspiel der Disputation
Authors: Sass Hartmut von
Published: August 2019

On the occation of the Leipzig Disputation 500 years ago, this paper deals with the genuinely theological relation between dispute and disputation, between disagreement and a culture handling that very disagreement. By way of introduction, three dogmatic doctrines will be consulted to regard disputes as institutions internal to faith (I.). This section is followed by considerations on disputations as language games to deal with this kind of dissensus in a structured and safeguarded way (II.). At the end, I will return to the Leipzig Disputation and its effects on a theological culture of disagreement; to do this, three inter-related claims will be presented: according to them, the event of 1519 could be viewed as a communicative re­volution. The discourse of theology has changed considerably by a sustainable transformation of what was and is meant by a disputatio in the first place (III.).
Politische Theologie und öffentliche Theologie
Authors: Moltmann Jürgen
Published: August 2019

Referring to the discussions on »Public Theology« in issue 1 of this volume of EvTh, Jürgen Moltmann recalls the »new political theology« to which, together with Johann Baptist Metz and others, he contributed in the 60th and 70th of the 20th century. Unlike this »Political Theology«, according to Moltmann, »Public Theology« does not primarily focus on a libera­ting practice but rather on the Church’s Impact on public discourse. Moltmann reminds the Church, however, not to neglect the content of the Christian message by only aiming at public attention and Impact.
Nicht nur aus der Not geboren
Authors: Garhammer Stephan
Published: August 2019

Überblick

Im Bistum Hildesheim wird eine neue Form des Personaleinsatzes in der Seelsorge eingeführt. Grundgedanken dieser neuen Form der Zusammenarbeit sind das Arbeiten im Team und die Einsicht, dass das pastorale Personal die Christinnen und Christen befähigt, Kirche vor Ort eigenverantwortlich zu gestalten. Den Weg hin zu dieser Form und eine erste Beschreibung des Personaleinsatzes stellt der nachfolgende Beitrag vor.
Wie geht's den Diakon*innen?
Authors: Schendel Gunther
Published: August 2019

Überblick

Der Beruf der Diakon*innen ist neu in den Blick geraten. An ihn knüpft sich die Hoffnung auf Brückenbauer*innen, die der Kirche neue Kontakte und eine neue Relevanz erschließen. In multiprofessionellen Teams sollen sie eine neue Rolle spielen. Aber wie ist aktuell die Berufsrealität der Diakon*innen? Dazu hat das Sozialwissenschaftliche Institut der EKD eine empirische Untersuchung in der Evangelisch-lutherischen Landeskirche Hannovers durchge­führt. Ihre Auswertung gibt Auskunft über Variablen, die für die Arbeitszufriedenheit wichtig sind, und zeigt die Spezialisierung und Differenzierung im Arbeitsfeld der Diakon*innen. Für die Diskussion um die weitere Entwicklung des Berufs sind die Erwartungen der Anstel­lungsträger von Bedeutung, die in Richtung einer verstärkten Sozialraumorientierung und des Verkündigens gehen.
Effects of weed management and plant arrangements on yield index of sweet sorghum
Authors: Reis Ronaldo Matias , Freitas Matheus Souza , Silva Daniel Valadão , Pereira Gustavo Antônio Mendes , Passos Ana Beatriz Rocha de Jesus , Silva Alexandre Ferreira , Silva Antonio Alberto da , Reis Marcelo Rodrigues dos
Published: August 2019

Sweet sorghum is currently an important alternative for ethanol production in sugar cane off-season. In this study was to evaluate the effects of plant arrangements and the application of atrazine and S-metolachlor on growth and productivity of sweet sorghum. An experiment was conducted in randomized block design and, arranged in split plots with four repetitions. Plots consisted of spacing (0.25 m, 0.45 m 0.45-0.45-0.90 m) and sub-plots of weed control methods - atrazine (2000 g ha-1), atrazine + S-metolachlor (2000 + 720 g ha-1), atrazine + S-metolachlor (2000 + 960 g ha-1), atrazine + S-metolachlor (2000 + 1200 g ha-1), atrazine + S-metolachlor (2000 + 1440 g ha-1). Besides that, manual hoeing control was added. The intoxication of sorghum plants and weed control was evaluated at 7, 14 e 28 days after herbicides application (DAA). Plant height, stem diameter, total fresh matter, juice mass and total soluble solids (°Brix) were evaluated at 120 days after crop emergence (DAE).  There was no interaction between the factors spacings and control method for variables total matter fresh (TMF), height (H), stem diameter (D), juice mass (JM), and Brix. Application of the mixture (atrazine + S-metolachlor) in the highest doses reduced total fresh matter and °Brix. The spacing of 0.25 m provided the highest productivity of fresh matter, juice mass and increased the °Brix. The application of mixture (atrazine + S-metolachlor) controlled 90% of the weeds at 28 days after application. The increasing in doses of S-metolachlor elevates the intoxication in sorghum plants. The mixture (atrazine + S-metolachlor) has a potential for use in weed control in sweet sorghum, but at doses below 960 g ha-1 of S-metolachlor.
metolachlor.
Does the surrounding vegetation influence the fruit fly assemblage in guava orchards?
Authors: Vargas Kátia da Cruz , Abot Alfredo Raúl , Acosta Victor Ribeiro , Telles Marcos Henrique Frech , Do Nascimento José Nicácio , Garcia Flávio Roberto Mello
Published: August 2019

This study aimed to evaluate how the surrounding vegetation affects the assemblage of fruit flies. For this, flies were collected in guava orchards with distinct types of surrounding vegetation (exotic pasture, native forest and fruit tree intercropping). The experiment was conducted in Itaporã and Dourados, State of Mato Grosso do Sul, Brazil. Weekly samples were collected from March to April 2015. McPhail traps were baited with 5% hydrolyzed corn protein. Species richness, diversity index and abundance were evaluated for each orchard, as well as the species composition of fruit fly between the environments surrounding the orchard and, finally, the sex ratio. A total of 579 individuals were collected of the species Anastrepha fraterculus, A. montei, A. obliqua, A. sororcula, A. striata, A. turpiniae and A. zenildae. The orchard surrounded by native forest had the highest species richness and Shannon diversity. The species composition differed between environments, with the formation of three distinct groups. The environment surrounding the guava orchard influences the richness, diversity, abundance and sex ratio of fruit flies, indicating that the native forest may provide more resources for the maintenance of these insects.
Conidia production of Isaria fumosorosea (Hypocreales: Cordycipitaceae) in organic substrates through two propagation techniques
Authors: Gandarilla-Pacheco Fatima Lizeth , Elías-Santos Myriam , Alemán-Huerta Maria Elizabeth , De Luna-Santillana Erick de Jesús , Quintero-Zapata Isela
Published: August 2019

In the last decades, the use of entomopathogenic fungi for the control of pest insects has increased globally, however a key step to achieve the successful application of fungal propagules as biocontrol agents depends of various factors, inoculum production being one of the essential stages for these microorganisms to be used in pest management programs. The objective of this study was to evaluate the production of conidia by solid fermentation and biphasic culture in different sporulation matrices for four native isolates and a strain of Isaria fumosorosea that have been shown potential for the control of various insects at the laboratory level. The experimental design was completely randomized, two propagation methods were used with six treatments and ten repetitions per treatment; the data were analyzed using an analysis of variance and the means were compared using the Tukey test (p≤ 0.05). In the production by solid fermentation the minimum value of 5.30 × 105 conidia g-1 was registered with the pericarp of peanut and the maximum of 2.35 × 107 conidia g-1 in the corn grain; in the biphasic culture the minimum of 7.60 × 105 conidia g-1 was observed in birdseed and the maximum of 2.07 × 107 conidia g-1 in rice. The differences were significant (p ≤ 0.05) in the production by method and by substrate, in solid fermentation 6.84 × 106 conidia g-1 and in biphasic culture 8.85 × 106 conidia g-1. In the production by substrate, the rice showed 1.75 × 107 conidia g-1 and the lesser canary seed concentration (7.80 × 105 conidia g-1). The average production per isolate and / or strain was of the order of 106 and significant difference was registered (p ≤ 0.05) among the fungi, the isolate HIB-9 showed concentration in average higher in the production (7.90 × 106 conidia g-1) and the isolated HIB-19 was the least effective, with only 1.08 × 106 conidia g-1. The results obtained show marked differences between the isolates with respect to their capacity to use the different substrates used as propagation media to obtain conidia of I. fumosorosea.