bluuebunny/crossref_metadata_2025 huggingface dataset:
A new source of root-knot nematode resistance from Arachis stenosperma incorporated into allotetraploid peanut (Arachis hypogaea)
Authors: Ballén-Taborda Carolina , Chu Ye , Ozias-Akins Peggy , Timper Patricia , Holbrook C. Corley , Jackson Scott A. , Bertioli David J. , Leal-Bertioli Soraya C. M.
Published: November 2019

Root-knot nematode is a very destructive pathogen, to which most peanut cultivars are highly susceptible. Strong resistance is present in the wild diploid peanut relatives. Previously, QTLs controlling nematode resistance were identified on chromosomes A02, A04 and A09 of Arachis stenosperma. Here, to study the inheritance of these resistance alleles within the genetic background of tetraploid peanut, an F2 population was developed from a cross between peanut and an induced allotetraploid that incorporated A. stenosperma, [Arachis batizocoi x A. stenosperma]4×. This population was genotyped using a SNP array and phenotyped for nematode resistance. QTL analysis allowed us to verify the major-effect QTL on chromosome A02 and a secondary QTL on A09, each contributing to a percentage reduction in nematode multiplication up to 98.2%. These were validated in selected F2:3 lines. The genome location of the large-effect QTL on A02 is rich in genes encoding TIR-NBS-LRR protein domains that are involved in plant defenses. We conclude that the strong resistance to RKN, derived from the diploid A. stenosperma, is transferrable and expressed in tetraploid peanut. Currently it is being used in breeding programs for introgressing a new source of nematode resistance and to widen the genetic basis of agronomically adapted peanut lines.
Efficient Control of THz Transmission of PEDOT:PSS with Resonant Nano-Metamaterials
Authors: Chaudhary Raghvendra P. , Das Bamadev , Oh Seugn In , Kim Dai-Sik
Published: November 2019

Nano-metamaterials designed to operate at a certain resonance frequency enhance the magnitude of terahertz (THz) wave transmission by three orders of magnitude or even more. In this pursuit, controlling magnitude of resonant transmission and tuning the resonance frequency is increasingly important for application in low power THz electronics and devices. THz optical properties of chemically doped poly(3,4‐ethylenedioxythiophene):poly(4‐styrenesulfonate) (PEDOT:PSS) have been studied, however its effect on the THz transmission properties in combination with nano-metamaterials have not yet been demonstrated. Here we demonstrate the efficient control over resonant THz transmission and tuning of resonance frequency of different nano-metamaterials using PEDOT:PSS, without any toxic chemical doping. By ease of simple solution processing with single step and drop-casting 10 μL aqueous solution of PEDOT:PSS on different nano-metamaterials with varied concentrations, we were able to dynamically control the THz transmission along with resonance frequency. This dynamic control of transmission and shift in resonance frequency can be attributed to improved conductivity of PEDOT:PSS and its interaction with strongly localized THz field of the metamaterial.
Mechanism and therapeutic effect of umbilical cord mesenchymal stem cells in inflammatory bowel disease
Authors: Pan Xing-hua , Li Qing-qing , Zhu Xiang-qing , Li Zi-an , Cai Xue-min , Pang Rong-qing , Ruan Guang-ping
Published: November 2019

Inflammatory bowel disease (IBD) is a persistent and chronic disease that is characterized by destructive gastrointestinal (GI) inflammation. Researchers are trying to identify and develop new and more effective treatments with no side effects. Acute and chronic mouse models of IBD were established using dextran sulfate sodium (DSS) solution. To evaluate the efficacy and mechanism, umbilical cord mesenchymal stem cells (UCMSCs) were obtained from Kunming (KM) mice and humans. In the chronic IBD study, the survival rates of the normal control, model, mouse UCMSC (mUCMSC) and human UCMSC (hUCMSC) groups were 100%, 40%, 86.7%, and 100%, respectively. The histopathological scores of the normal control, intraperitoneal injection, intravenous treatment, and model groups were 0.5 ± 0.30, 5.9 ± 1.10, 8.7 ± 1.39, and 8.8 ± 1.33 (p = 0.021). UCMSCs promoted the expression of the intestinal tight junction protein occludin, downregulated the protein expression of the autophagy marker LC3A/B in colon tissue, and upregulated the expression of VEGF-A and VEGFR-1 at the injured site. This study provides an experimental model for elucidating the therapeutic effects of UCMSCs in IBD. We provide a theoretical basis and method for the clinical treatment of IBD using UCMSCs.
Strain improvement of Escherichia coli K-12 for recombinant production of deuterated proteins
Authors: Kelpšas Vinardas , Wachenfeldt Claes von
Published: November 2019

Deuterium isotope labelling is important for structural biology methods such as neutron protein crystallography, nuclear magnetic resonance and small angle neutron scattering studies of proteins. Deuterium is a natural low abundance stable hydrogen isotope that in high concentrations negatively affect growth of cells. The generation time for Escherichia coli K-12 in deuterated medium is substantially increased compared to cells grown in hydrogenated (protiated) medium. By using a mutagenesis plasmid based approach we have isolated an E. coli strain derived from E. coli K-12 substrain MG1655 that show increased fitness in deuterium based growth media, without general adaptation to media components. By whole-genome sequencing we identified the genomic changes in the obtained strain and show that it can be used for recombinant production of perdeuterated proteins in amounts typically needed for structural biology studies.
RSH enzyme diversity for (p)ppGpp metabolism in Phaeodactylum tricornutum and other diatoms
Authors: Avilan Luisana , Puppo Carine , Villain Adrien , Bouveret Emanuelle , Menand Benoit , Field Ben , Gontero Brigitte
Published: November 2019

The nucleotides guanosine tetraphosphate and pentaphosphate (together known as (p)ppGpp or magic spot) are produced in plant plastids from GDP/GTP and ATP by RelA-SpoT homologue (RSH) enzymes. In the model plant Arabidopsis (p)ppGpp regulates chloroplast transcription and translation to affect growth, and is also implicated in acclimation to stress. However, little is known about (p)ppGpp metabolism or its evolution in other photosynthetic eukaryotes. Here we studied (p)ppGpp metabolism in the marine diatom Phaeodactylum tricornutum. We identified three expressed RSH genes in the P. tricornutum genome, and determined the enzymatic activity of the corresponding enzymes by heterologous expression in bacteria. We showed that two P. tricornutum RSH are (p)ppGpp synthetases, despite substitution of a residue within the active site believed critical for activity, and that the third RSH is a bifunctional (p)ppGpp synthetase and hydrolase, the first of its kind demonstrated in a photosynthetic eukaryote. A broad phylogenetic analysis then showed that diatom RSH belong to novel algal RSH clades. Together our work significantly expands the horizons of (p)ppGpp signalling in the photosynthetic eukaryotes by demonstrating an unexpected functional, structural and evolutionary diversity in RSH enzymes from organisms with plastids derived from red algae.
Global ocean freshening, ocean mass increase and global mean sea level rise over 2005–2015
Authors: Llovel William , Purkey S. , Meyssignac B. , Blazquez A. , Kolodziejczyk N. , Bamber J.
Published: November 2019

Global mean sea level has experienced an unabated rise over the 20th century. This observed rise is due to both ocean warming and increasing continental freshwater discharge. We estimate the net ocean mass contribution to sea level by assessing the global ocean salt budget based on the unprecedented amount of in situ data over 2005–2015. We obtain the ocean mass trends of 1.30 ± 1.13 mm · yr−1 (0–2000 m) and 1.55 ± 1.20 mm · yr−1 (full depth). These new ocean mass trends are smaller by 0.63–0.88 mm · yr−1 compared to the ocean mass trend estimated through the sea level budget approach. Our result provides an independent validation of Gravity Recovery And Climate Experiment (GRACE)-based ocean mass trend and, in addition, places an independent constraint on the combined Glacial Isostatic Adjustment – the Earth’s delayed viscoelastic response to the redistribution of mass that accompanied the last deglaciation- and geocenter variations needed to directly infer the ocean mass trend based on GRACE data.
Wide field imaging energy dispersive X-ray absorption spectroscopy
Authors: Qi Peng , Samadi Nazanin , Martinson Mercedes , Ponomarenko Olena , Bassey Bassey , Gomez Ariel , George Graham N. , Pickering Ingrid J. , Chapman L. Dean
Published: November 2019

A new energy dispersive X-ray absorption spectroscopy (EDXAS) method is presented for simultaneous wide-field imaging and transmission X-ray absorption spectroscopy (XAS) to enable rapid imaging and speciation of elements. Based on spectral K-Edge Subtraction imaging (sKES), a bent Laue imaging system diffracting in the vertical plane was developed on a bend magnet beamline for selenium speciation. The high flux and small vertical focus, forming a wide horizontal line beam for projection imaging and computed tomography applications, is achieved by precise matching of lattice plane orientation and crystal surface (asymmetry angle). The condition generating a small vertical focus for imaging also provides good energy dispersion. Details for achieving sufficient energy and spatial resolution are demonstrated for both full field imaging and computed tomography in quantifying selenium chemical species. While this system has lower sensitivity as it uses transmission and may lack the flux and spatial resolution of a dedicated focused beamline system, it has significant potential in rapid screening of heterogeneous biomedical or environmental systems to correlate metal speciation with function.
Author Correction: Performance of a glucose-reactive enzyme-based biofuel cell system for biomedical applications
Authors: Jeon Won-Yong , Lee Jung-Hwan , Dashnyam Khandmaa , Choi Young-Bong , Kim Tae-Hyun , Lee Hae-Hyoung , Kim Hae-Won , Kim Hyug-Han
Published: November 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Author Correction: Growth and longevity in giant barrel sponges: Redwoods of the reef or Pines in the Indo-Pacific?
Authors: McGrath Emily C. , Woods Lisa , Jompa Jamaluddin , Haris Abdul , Bell James J.
Published: November 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Publisher Correction: Characterization of irreversible electroporation on the stomach: A feasibility study in rats
Authors: Lee Jae Min , Choi Hyuk Soon , Kim Eun Sun , Keum Bora , Seo Yeon Seok , Jeen Yoon Tae , Lee Hong Sik , Chun Hoon Jai , Um Soon Ho , Kim Chang Duck , Kim Hong Bae
Published: November 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Irradiation induces p53 loss of heterozygosity in breast cancer expressing mutant p53
Authors: Ghaleb Amr , Yallowitz Alisha , Marchenko Natalia
Published: November 2019

Mutations in one allele of the TP53 gene in cancer early stages are frequently followed by the loss of the remaining wild-type allele (LOH) during tumor progression. However, the clinical impact of TP53 mutations and p53LOH, especially in the context of genotoxic modalities, remains unclear. Using MMTV;ErbB2 model carrying a heterozygous R172H p53 mutation, we report a previously unidentified oncogenic activity of mutant p53 (mutp53): the exacerbation of p53LOH after irradiation. We show that wild-type p53 allele is partially transcriptionally competent and enables the maintenance of the genomic integrity under normal conditions in mutp53 heterozygous cells. In heterozygous cells γ-irradiation promotes mutp53 stabilization, which suppresses DNA repair and the cell cycle checkpoint allowing cell cycle progression in the presence of inefficiently repaired DNA, consequently increases genomic instability leading to p53LOH. Hence, in mutp53 heterozygous cells, irradiation facilitates the selective pressure for p53LOH that enhances cancer cell fitness and provides the genetic plasticity for acquiring metastatic properties.
A high throughput screening method for endocrine disrupting chemicals in tap water and milk samples based on estrogen receptor α and gold nanoparticles
Authors: Liu Mengyue , Zhang Shengqiang , Du Shuyuan , Pang Shuxue , Liu Xiaoyu , Zhang Hongyan
Published: November 2019

Increasing concern over endocrine disrupting chemicals (EDCs) in environmental and food samples has created the demand for rapid and high throughput screening methods to evaluate their estrogenic effects.
In situ hemolysis in a three-dimensional paper-based device for quantification of intraerythrocytic analytes
Authors: Baillargeon Keith R. , Bricknell Jordan R. , Mace Charles R.
Published: November 2019

Quantitative in situ hemolysis is achieved for samples of whole blood using a chemical treatment without additional user-steps or sample preparation.
Metal-free α-arylation of α-fluoro-α-nitroacetamides employing diaryliodonium salts
Authors: Zaheer Mohd Khalid , Gupta Ekta , Kant Ruchir , Mohanan Kishor
Published: November 2019

A mild and efficient metal-free arylation of α-fluoro-α-nitroacetamides employing diaryliodonium salts has been developed.
Low-loading Pt nanoparticles embedded on Ni, N-doped carbon as superior electrocatalysts for oxygen reduction
Authors: Wang Xinliang , Yang Shaoxuan , Yu Yihuan , Dou Meiling , Zhang Zhengping , Wang Feng
Published: November 2019

A synergetic catalytic system was built based on Pt NPs and atomic Ni–N–C joint active sites for better ORR electrocatalysis.
The fabrication of trifunctional polyoxometalate hybrids for the cascade conversion of glycerol to lactic acid
Authors: Tao Meilin , Sun Ningyue , Li Yiming , Wang Shengtian , Wang Xiaohong
Published: November 2019

Lactic acid (LA) has been produced with cascade reactions under non-noble metal and base-free conditions.
Cu carbonyls enhance the performance of Ru-based SILP water–gas shift catalysts: a combinedin situDRIFTS and DFT study
Authors: Blaumeiser Dominik , Stepić Robert , Wolf Patrick , Wick Christian R. , Haumann Marco , Wasserscheid Peter , Smith David M. , Smith Ana-Sunčana , Bauer Tanja , Libuda Jörg
Published: November 2019

In situDRIFT spectroscopy and DFT identify Cu carbonyl shuttles that enhance the performance of Ru-based SILP water–gas shift catalysts.
Theoretical investigation on the hydrogen evolution reaction mechanism at MoS2 heterostructures: the essential role of the 1T/2H phase interface
Authors: Zhang Tian , Zhu Houyu , Guo Chen , Cao Shoufu , Wu Chi-Man Lawrence , Wang Zhaojie , Lu Xiaoqing
Published: November 2019

DFT calculations have been performed to study the HER mechanism at 1T/2H MoS2 heterostructures. The HER activity along the 1T/2H phase interface is comparable with those at the Mo-edge of 2H MoS2 and the basal plane of 1T MoS2.
Selective, bifunctional Cu–WOx/Al2O3 catalyst for hydrodeoxygenation of fatty acids
Authors: Janampelli Sagar , Sethia Govind , Darbha Srinivas
Published: November 2019

Cu–WOx/Al2O3 is highly selective for hydrodeoxygenation of oleic acid. Texture and acidity influenced the catalyst activity.
The displacement reaction mechanism of the CuV2O6 nanowire cathode for rechargeable aqueous zinc ion batteries
Authors: Yu Xin , Hu Fang , Cui Fuhan , Zhao Jun , Guan Chao , Zhu Kai
Published: November 2019

CuV2O6 nanowires as a cathode material for Zn-ion batteries display an initial discharge capacity of 338 mA h g−1 at a current density of 100 mA g−1 and an excellent cycle performance after 1200 cycles at 5 A g−1.
Design of a mixed conductive garnet/Li interface for dendrite-free solid lithium metal batteries
Authors: Huo Hanyu , Chen Yue , Li Ruying , Zhao Ning , Luo Jing , Pereira da Silva João Gustavo , Mücke Robert , Kaghazchi Payam , Guo Xiangxin , Sun Xueliang
Published: November 2019

A mixed conductive garnet/Li interface consisting of electronic conductive nanoparticles embedded in an ionic conductive network is constructed for dendrite-free solid garnet batteries.
All-weather-available, continuous steam generation based on the synergistic photo-thermal and electro-thermal conversion by MXene-based aerogels
Authors: Zhao Xing , Peng Li-Mei , Tang Chun-Yan , Pu Jun-Hong , Zha Xiang-Jun , Ke Kai , Bao Rui-Ying , Yang Ming-Bo , Yang Wei
Published: November 2019

An all-weather steam generation system is achieved based on the alternative photo-thermal and electro-thermal conversion of crosslinked MXene aerogels.
Ultra-small intermetallic NiZn nanoparticles: a non-precious metal catalyst for efficient electrocatalysis
Authors: Samanta Arnab , Das Sankar , Jana Subhra
Published: November 2019

Ultra-small monodisperse intermetallic NiZn nanoparticles synthesized via a low-temperature solution chemistry route possess enhanced electrocatalytic activity during the oxygen evolution reaction.
Probing the local structure of nanoscale actinide oxides: a comparison between PuO2 and ThO2 nanoparticles rules out PuO2+x hypothesis
Authors: Bonato Laura , Virot Matthieu , Dumas Thomas , Mesbah Adel , Dalodière Elodie , Dieste Blanco Oliver , Wiss Thierry , Le Goff Xavier , Odorico Michael , Prieur Damien , Rossberg André , Venault Laurent , Dacheux Nicolas , Moisy Philippe , Nikitenko Sergey I.
Published: November 2019

XRD, EXAFS and HR-TEM study reveals a strong correlation between AnO2 (An = Th and Pu) nanoparticle size and An(iv) local structure.
A simple yet effective AIE-based fluorescent nano-thermometer for temperature mapping in living cells using fluorescence lifetime imaging microscopy
Authors: Gao Hui , Kam Chuen , Chou Tsu Yu , Wu Ming-Yu , Zhao Xin , Chen Sijie
Published: November 2019

A novel nano-thermometer composed of butter and AIE molecules can be used for intracellular temperature mapping using fluorescence lifetime imaging.
Optoelectronic parameters of peripherally tetra-substituted copper(ii) phthalocyanines and fabrication of a photoconductive diode for various conditions
Authors: Günsel Armağan , Bilgiçli Ahmet T. , Tüzün Burak , Pişkin Hasan , Yarasir M. Nilüfer , Gündüz Bayram
Published: November 2019

In this study, the molecular structure of 4-(4-(trifluoromethoxy)phenoxy)phthalonitrile (1) has been elucidated and its supra-molecular dynamics have been revealed by the analysis of single crystal X-ray diffraction measurements.
A fluorescence probe based on 6-phenylimidazo[2,1-b]thiazole and salicylaldehyde for the relay discerning of In3+ and Cr3+
Authors: Li Bing , Shang Xiaodong , Li Linlin , Xu Yuankang , Wang Hanyu , Yang Xiaofeng , Pei Meishan , Zhang Ruiqing , Zhang Guangyou
Published: November 2019

A new fluorescence probe, (E)-N′-(2-hydroxybenzylidene)-6-phenylimidazo[2,1-b]thiazole-3-carbohydrazide (LB1), based on 6-phenylimidazo[2,1-b]thiazole and salicylaldehyde was designed and synthesized.
Biomineralization synthesis of a near-infrared fluorescent nanoprobe for direct glucose sensing in whole blood
Authors: Deng Honghua , Liu Huiqiong , Kang Wenyuan , Lei Chunyang , Nie Zhou , Huang Yan , Yao Shouzhuo
Published: November 2019

A near-infrared fluorescent nanoprobe based on protein-templated biomineralization synthesis is presented for direct glucose sensing in whole blood.
Skin irritation potential of graphene-based materials using a non-animal test
Authors: Fusco Laura , Garrido Marina , Martín Cristina , Sosa Silvio , Ponti Cristina , Centeno Alba , Alonso Beatriz , Zurutuza Amaia , Vázquez Ester , Tubaro Aurelia , Prato Maurizio , Pelin Marco
Published: November 2019

Graphene related materials, if prepared with non-irritant exfoliation agents, do not induce skin irritation on a 3D model of human epidermis, following the OECD guideline 439.
Negative effective excitonic diffusion in monolayer transition metal dichalcogenides
Authors: Rosati Roberto , Perea-Causín Raül , Brem Samuel , Malic Ermin
Published: November 2019

The bright exciton propagation in monolayers of transition metal dichalcogenides (TMDs) shows at low temperatures a shrinking of the spatial profile, i.e. negative effective diffusion due to intervalley scattering in the TMDs excitonic landscape.
ZnO nanowire-integrated bio-microchips for specific capture and non-destructive release of circulating tumor cells
Authors: Cui Heng , Liu Qing , Li Rui , Wei Xiaoyun , Sun Yue , Wang Zixiang , Zhang Lingling , Zhao Xing-Zhong , Hua Bo , Guo Shi-Shang
Published: November 2019

We constructed ZnO-coated gear structure PDMS pillars microchips that simultaneously combine the advantages of a micro/nano-structure. The microchip is designed to sensitively capture and non-destructively release CTCs using ZnO nanowires.
Biodegradable hollow manganese/cobalt oxide nanoparticles for tumor theranostics
Authors: Ren Qilong , Yang Kuikun , Zou Rujia , Wan Zhiping , Shen Zheyu , Wu Guangyu , Zhou Zijian , Ni Qianqian , Fan Wenpei , Hu Junqing , Liu Yijing
Published: November 2019

A simple strategy to synthesize manganese/cobalt oxide nanoparticles and their application as a GSH-responsive nanoscale drug delivery system were reported.
Plasmonic metamaterials for chiral sensing applications
Authors: Lee Yoon Young , Kim Ryeong Myeong , Im Sang Won , Balamurugan Mani , Nam Ki Tae
Published: November 2019

Here, we will discuss the principles of recent issues in chiral sensing of plasmonic metamaterials, including suggested formulas for signal enhancement of chiral plasmonic sensors, and studies on platforms that employ different sensing mechanisms.
Mechanisms behind excitation- and concentration-dependent multicolor photoluminescence in graphene quantum dots
Authors: Lai Shuangquan , Jin Yong , Shi Liangjie , Zhou Rong , Zhou Yutang , An Dexin
Published: November 2019

The excitation- and concentration-dependent multicolor emissions in GQDs were dominated by the charge transfer and self-aggregation of GQDs.
Use of lung-specific exosomes for miRNA-126 delivery in non-small cell lung cancer
Authors: Nie Huifang , Xie Xiaodong , Zhang Doudou , Zhou Yu , Li Bifei , Li Fengqiao , Li Feiyang , Cheng Yunlong , Mei Hao , Meng Huan , Jia Lee
Published: November 2019

Engineered exosomes have become popular drug delivery carriers for cancer treatment. Systemic injection of organotropic exosome carrier leads to efficient targeting and efficacious anti-cancer outcome.
The effect of spermidine on guanine decomposition via photoinduced electron transfer in DNA
Authors: Esumi Mayu , Sakurai Shunsuke , Tanaka Makiko
Published: November 2019

The addition of spermidine caused the attenuation of guanine decomposition via photoinduced electron transfer in pyrene-modified DNA, and higher added concentrations of spermidine resulted in the promotion of decomposition in condensed DNA.
From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3)
Authors: Lassagne Frédéric , Duguépéroux Camille , Roca Carlos , Perez Concepcion , Martinez Ana , Baratte Blandine , Robert Thomas , Ruchaud Sandrine , Bach Stéphane , Erb William , Roisnel Thierry , Mongin Florence
Published: November 2019

New potent inhibitors of protein kinase GSK3α were synthesized from 6-amino-3-chloroquinoxaline.
Processable epoxy-telechelic polyalkenamers and polyolefins for photocurable elastomers
Authors: Kassekert Luke A. , Dingwell Claire E. , De Hoe Guilhem X. , Hillmyer Marc A.
Published: November 2019

Processable epoxy-telechelic polyalkenamers and polyolefins were synthesized using ring-opening metathesis polymerization and photochemically cured to furnish the corresponding crosslinked elastomers.
NO reduction over an Al-embedded MoS2 monolayer: a first-principles study
Authors: Esrafili Mehdi D. , Heydari Safa
Published: November 2019

By performing first-principles calculations, we introduce a stable and novel catalyst for the conversion of NO and CO molecules into N2O and CO2 using Al-doped MoS2.
Nanofluidic devices prepared by an atomic force microscopy-based single-scratch approach
Authors: Yan Yongda , Wang Jiqiang , Chang Shunyu , Geng Yanquan , Chen Leyi , Gan Yang
Published: November 2019

A nanofluidic chip was prepared based on a commercial AFM system. Effects on ion transport and enzymatic reaction specificity were demonstrated.
Ionic conductivity of melt-frozen LiBH4 films
Authors: Trück J. , Hadjixenophontos E. , Joshi Yug , Richter G. , Stender P. , Schmitz G.
Published: November 2019

LiBH4 melt-frozen film as solid state electrolyte.
Toward realistic computer modeling of paraffin-based composite materials: critical assessment of atomic-scale models of paraffins
Authors: Glova Artyom D. , Volgin Igor V. , Nazarychev Victor M. , Larin Sergey V. , Lyulin Sergey V. , Gurtovenko Andrey A.
Published: November 2019

Atomic-scale computational models of paraffins are critically assessed and compared.
Nafion film transport properties in a low-Pt PEM fuel cell: impedance spectroscopy study
Authors: Reshetenko Tatyana , Kulikovsky Andrei
Published: November 2019

A model for PEM fuel cell impedance taking into account oxygen transport through the Nafion film covering Pt/C aggolmerates is developed and used for fitting experimental spectra of a low-Pt cell.
The synergetic effect of a structure-engineered mesoporous SiO2–ZnO composite for doxycycline adsorption
Authors: Huang Danya , Zhang Ying , Zhang Jingjing , Wang Hongli , Wang Minggang , Wu Chen , Cheng Daowen , Chi Yue , Zhao Zhankui
Published: November 2019

The design and synthesis of an efficient adsorbent for antibiotics-based pollutants is challenging due to the unique physicochemical properties of antibiotics.
NIR nanoprobe-facilitated cross-referencing manifestation of local disease biology for dynamic therapeutic response assessment
Authors: Wang Zhimin , Ai Xiangzhao , Zhang Zhijun , Wang Yong , Wu Xiangyang , Haindl Richard , Yeow Edwin K. L. , Drexler Wolfgang , Gao Mingyuan , Xing Bengang
Published: November 2019

NIR photoacoustic and upconversion luminescent nanoprobe-facilitated cross-referencing manifestation of oxidative stress-induced liver pathophysiology for dynamic therapeutic response assessment.
Oxygen accelerated scalable synthesis of highly fluorescent sulfur quantum dots
Authors: Song Yiheng , Tan Jisuan , Wang Guan , Gao Pengxiang , Lei Jiehao , Zhou Li
Published: November 2019

Highly fluorescent sulfur quantum dots could be rapidly and massively synthesized from inexpensive elemental sulfur under a pure O2 atmosphere.
An insight into perovskite-based photocatalysts for artificial photosynthesis
Authors: Teh Yee Wen , Chee Michell K. T. , Kong Xin Ying , Yong Siek-Ting , Chai Siang-Piao
Published: November 2019

Schematic illustration of perovskite-based photocatalysts for artificial photosynthesis.
On the role of flexibility in linker-mediated DNA hydrogels
Authors: Stoev Iliya D. , Cao Tianyang , Caciagli Alessio , Yu Jiaming , Ness Christopher , Liu Ren , Ghosh Rini , O’Neill Thomas , Liu Dongsheng , Eiser Erika
Published: November 2019

DNA nanostars with sticky, single-stranded DNA overhangs, are known to form thermally reversible, viscoelastic networks. Here we show that introducing the right flexibility will rather lead to a cluster phase with a much reduced viscosity then an elastic hydrogel.
Deep learning for automated classification and characterization of amorphous materials
Authors: Swanson Kirk , Trivedi Shubhendu , Lequieu Joshua , Swanson Kyle , Kondor Risi
Published: November 2019

We use deep learning to automatically classify liquid and glass structures and to derive novel metrics that describe glass formation.
Stepwise structural and fluorescent colour conversion in rhodamine analogues based on light and acid stimulations
Authors: Tanioka Masaru , Kamino Shinichiro , Koga Natsumi , Sawada Daisuke
Published: November 2019

The research and development of multi-stimuli, multi-responsive molecules have attracted considerable attention in chemistry, biology, and material science. Herein, we propose a multi-stimuli-responsive multi-fluorescence system in a single molecule.
Oxygen vacancy engineering of self-doped SnO2−xnanocrystals for ultrasensitive NO2detection
Authors: Shao Meng , Liu Jiajia , Ding Wenjie , Wang Jingyu , Dong Fan , Zhang Jiatao
Published: November 2019

Self-doping of SnO2−xnanocrystals accompanying abundant oxygen vacancies results in significant enhancement in the gas sensing performance.
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators
Authors: Lusvarghi Sabrina , Ambudkar Suresh V.
Published: November 2019

P-glycoprotein (P-gp), an ATP-binding cassette transporter associated with multidrug resistance in cancer cells, is capable of effluxing a number of xenobiotics as well as anticancer drugs. The transport of molecules through the transmembrane (TM) region of P-gp involves orchestrated conformational changes between inward-open and inward-closed forms, the details of which are still being worked out. Here, we assessed how the binding of transport substrates or modulators in the TM region and the binding of ATP to the nucleotide-binding domains (NBDs) affect the thermostability of P-gp in a membrane environment. P-gp stability after exposure at high temperatures (37–80°C) was assessed by measuring ATPase activity and loss of monomeric P-gp. Our results show that P-gp is significantly thermostabilized (>22°C higher IT50) by the binding of ATP under non-hydrolyzing conditions (in the absence of Mg2+). By using an ATP-binding-deficient mutant (Y401A) and a hydrolysis-deficient mutant (E556Q/E1201Q), we show that thermostabilization of P-gp requires binding of ATP to both NBDs and their dimerization. Additionally, we found that transport substrates do not affect the thermal stability of P-gp either in the absence or presence of ATP; in contrast, inhibitors of P-gp including tariquidar and zosuquidar prevent ATP-dependent thermostabilization in a concentration-dependent manner, by stabilizing the inward-open conformation. Altogether, our data suggest that modulators, which bind in the TM regions, inhibit ATP hydrolysis and drug transport by preventing the ATP-dependent dimerization of the NBDs of P-gp.
Double‐sided bidding strategy for power suppliers and large buyers with amalgamation of wind and solar based generation in a modern energy market
Authors: Singh Satyendra , Fozdar Manoj
Published: November 2019

The deployment of renewable energy sources has been rapidly increasing due to environmental constraints but renewable electricity suppliers face an inevitable problem of uncertainty which is caused by the intermittent nature of renewable sources. In real‐time operation, compromises have been made in cost and power to balance the power which reduces supplier benefits. Therefore, the functions of Weibull and Beta distribution of probability are used to handle the adverse impact of wind speed uncertainty and solar irradiation, respectively, and scenarios are reduced using the forward‐reduction algorithm. Moreover, to measure the deviation of renewable power, underestimation and overestimation cost functions are utilised. This study proposes a suitable double‐sided strategic bidding problem as a multi‐objective optimisation problem to maximise the profits of suppliers and buyers to minimise uncertainty of rivals and renewable power. The formulated problem is solved by Technique for Order of Preference by Similarity to Ideal Solution along with Gravitational Search Algorithm, and simulation results are obtained in absence and presence of both solar and wind power on IEEE standard 30‐bus and 57‐bus test systems. The obtained results prove the suitability of the proposed bidding strategy in the presence of uncertainty of solar and wind power.
10 cm range small-size reference microwave oscillator on a coaxial resonator with a PLL and a low level of phase noise
Authors: Samokhin Sergey , Goryunov Ivan , Iovdalskiy Viktor , Teryoshkin Еvgeniy , Fyodorov Nikolay
Published: November 2019

The results of development and modernization of a high-stable small-size reference microwave oscillator with a PLL and a low level of phase noise for use in special purpose equipment with an operating frequency of 3.6 GHz, phase noise (with 2 kHz offset) of -112 dBc/Hz and output power from 0 to 40 mW are presented.
5G base station prototyping: implementation possibilities in Russia
Authors: Ponomarev Oleg , Moiseichenkov Alexander , Bakhtin Alexander , Omelyanchuk Elena , Semenova Anastasia , Mikhailov Victor
Published: November 2019

A brief overview of the development of 5G mobile communications in the world and in Russia is presented. 5G pilot projects in Russia are considered. The basic requirements for 5G networks, the tasks facing developers, examples of hardware and brief technical specifications of hardware produced in Russia that can be used to create base station equipment for 5G networks are given. The work of MIET on the development of software and algorithmic support for 5G transceiver equipment is described. An estimation is given concerning the feasibility of implementing 5G generation mobile communication base stations in Russia, including on the basis of hardware from Russian manufacturers.
Features of navigational radiosonde coordinate data processing for high resolution windfinding
Authors: Plokhikh Oleg
Published: November 2019

Upper-air sounding systems (UASS) are the main means of obtaining aerological information to provide short-term and long-term weather forecasts, prevention of natural and anthropogenic catastrophes, etc. The UASS uses the principle of tracking a radiosonde launched into free flight, usually using a gas-filled balloon. Radiosondes are equipped with various sensors for measuring atmospheric parameters. The balloon, in addition to the means of the radiosonde delivery, serves as a horizontal wind sensor. At the end of the 20th century, theodolites and radars were used to track the radiosonde. In the 90s, such companies as Air, Vaisala, Graw, etc. developed UASSs using signals from the American Global Positioning System (GPS). These systems have fundamental advantages in terms of efficiency, size, mobility, radiosonde positioning accuracy and operation on mobile platforms. The use of Global Navigation Satellite System (GNSS) in upper-air sounding systems offer new perspectives of fine wind field measuring and detecting turbulent layers. The navigation radiosonde provides more detailed and high-quality information. The processing of such data has its own specificity in comparison with radar UASS. This paper discusses the coordinate data processing of a navigational radiosonde. To analyze the errors in estimating the wind speed, computer simulation of a balloon-sonde system is used. The coordinate data filter parameters and filtering efficiency was refined during the simulation.
Design of clock and data recovery system’s behavioral model for high speed transceivers of serial interfaces
Authors: Dubinskiy Alexey V. , Domozhakov Denis A. , Rannev Nikolay Yu.
Published: November 2019

This paper provides a parameterizable behavioral model of a clock and data recovery system (CDR) based on phase-locked loop (PLL) for the receiver part of a high-speed serial interfaces. The model was used to calculate parameters and characteristics of the system as well as estimate their calculation error depending on the sub-circuit characteristics taken into account. A model structure was selected based on the obtained jitter estimation error. The model complies with all the accuracy and speed requirements to calculations of the characteristics of a PLL-CDR system for a receiver block with data transmission bit rates above 3.125 Gbit/s.
The criterion for the existence of the weight of the orthogonality of equidistant elementary signals
Authors: Degtyaryov Andrey
Published: November 2019

To reduce the level of intersymbol interference and interchannel interference, it is proposed to form the transmitted signals using the basis functions obtained by shifting the impulse responses of linear systems by multiple time intervals. An algorithm for calculating the weight of the orthogonality of basis functions is proposed. A criterion for the existence of the indicated weight of orthogonality is formulated.
Antenna systems for small spacecraft radio data communication channels
Authors: Generalov Alexander , Gadzhiev Elchin , Ovchinnikova Elena , To Nguen Dinh , Kondratieva Svetlana , Shmachilin Pavel
Published: November 2019

Antenna-feeder devices are used on spacecraft, which are part of various on-board systems and complexes. One such system is a radio communication channel for transmitting target information. A model of the aerial array of the radio data communication of target information from waveguide transmitters is developed and its characteristics are determined.
Concept of using structure magnonic crystal – ferroelectric – magnonic crystal as logic gate
Authors: Matveev Oleg , Morozova Maria
Published: November 2019

The features of the propagation of spin waves in a composite multiferroic structure consisting of two magnonic crystals and a ferroelectric layer are considered. During the propagation of spin waves in such a structure, the formation of band gaps takes place, the position of which depends on the method of excitation of coupled structure and dielectric constant of ferroelectric. This effect can be taken as the basis for the operation of a logical element that allows implementing AND and OR operators. The results of theoretical and experimental studies of spin-wave processes in this structure are presented.
Research and development of high-speed on-chip photodetectors based on AIIIBV heterostructures
Authors: Pisarenko Ivan , Ryndin Eugeny
Published: November 2019

This paper is aimed at the solution of the fundamental scientific and technical problem of research and development of high-performance optoelectronic devices designed for on- and inter-chip optical interconnecting in integrated circuits. Previously, we developed a laser with a double AIIIBV nanoheterostructure and a functionally integrated optical modulator. The device is based on the principle of controlled spatial relocation of charge carrier density peaks within quantum regions and provides the generation of optical signals with high modulation frequencies. The detection of short laser pulses generated by the lasermodulator requires a technologically compatible on-chip photodetector with subpicosecond response time. To meet the given requirements, we propose a novel design of a high-speed photodetector that employs the same relocation principle as the laser-modulator. The photodetector contains a traditional p-i-n photosensitive structure and an orthogonally oriented control heterostructure. During the back edge of a laser pulse, the control heterostructure displaces the peaks of electron and hole densities into special low-temperature-grown regions with short lifetimes and low carrier mobilities. We developed the quantum mechanical numerical model of the photodetector with controlled relocation of carrier density peaks and estimated the duration of the photocurrent back edge.
Features of mode selection in a combined Fabry-Perot cavity with distributed feedback of counter-propagating waves
Authors: Kocharovskaya Ekaterina , Mishin Alexey , Ryabinin Ivan
Published: November 2019

An analysis is made of the possibility of isolating relatively high-Q modes or groups of such modes in low-Q combined Fabry-Perot cavities with distributed feedback of counter-propagating waves in order to ensure resonant interaction of the electromagnetic field with the polarization oscillations of an amplifying or absorbing medium filling the cavity. We considered two-level active media with homogeneous or inhomogeneous broadening of a spectral line, which can be both smaller or larger than the photon bandgap of a cavity. Particular attention is paid to the change in the well-known spectrum of polariton modes which takes place due to the transition from an absorbing to an amplifying medium under conditions that allow the realization of spontaneous or laser generation of the so-called superradiant modes.
Surface topologies of thin aluminum films and absorbing properties of metal dielectric structures in the microwave range
Authors: Fitaev Ibraim Shevketovich , Orlenson Vulf Borisrvich , Romanets Yuri Viktorovich , Mazinov Alim Seit-Ametovich
Published: November 2019

The paper presents experimental and theoretical results on the surface topography of thin aluminum films. The ambiguous topology dynamics of the thin-film structure is represented as a function of the increase in the bulk mass of the deposited material, which leads to an occasional rise in roughness reaching its maximum at a film thickness of 7 nm. At same time on the same thickness of the conductive layer the maximum of the absorption coefficient variability is observed. A theoretical analysis of the optical coefficients depending on the size of the conductive film substantiated the existence of extremes, but at smaller thicknesses.
Using probabilistic fuzzy models for the prediction of functional failures of microwave LSI with radiation exposure
Authors: Barbashov Vyacheslav , Trushkin Nikolai , Osipov Aleksei
Published: November 2019

The article presents an analysis of microwave LSI behavior under radiation exposure at the functional-logical level of description. The analysis is based on fuzzy digital automaton and topological probabilistic models of workability assessment. It is shown that in certain cases both deterministic and non-deterministic failures are typical. Each operation threshold in logic elements under radiation influence has a zone of uncertainty and can be expressed quantitatively by a fuzzy number. This case, the real nature of microwave LSI radiation behavior is determined by the specific ratio of radiation-sensitive parameters of its elements and by taking into account the influence of their statistical scatter. Methods are proposed for simulating failures of microwave LSI under radiation exposure that are based on the model of a fuzzy digital Brauer automaton and a probabilistic reliability automaton.
Dynamic range extension method for microwave power meters
Authors: Cherepanov Alexander , Dobrikov Alexander , Zagorodny Andrew
Published: November 2019

The paper is devoted to microwave power meters, detector blocks of which can be located directly on the main PC board. The block diagram with dynamic range extension method was shown. Portable PLS series power meters with frequency range from 50 MHz to 6 GHz produced by Micran Company is presented. Galvanic isolation unit is proposed.
Scheme features of radio pulse gating for radar measurements
Authors: Zakharchenko Vladimir , Khoperskov Alexander
Published: November 2019

The model of a radio pulse stroboscopic converter consisting of a mixer and a narrowband filter tuned to the difference frequency of the carrier signals is considered. We demonstrate that the measurement of the phase structure of the input signals can be made at low frequency by amplitude methods by changing the phase both in the channel of the gating radio pulses and in the low frequency channel. The radio-pulse gating scheme goes into a phase-sensitive mode when the system clock frequency is synchronized with the second harmonic of the difference frequency, however, in this case, a parasitic phase modulation occurs in the converted signal, which does not depend on the transformation coefficient of the spectrum and is determined only by the duty cycle of the input signal. To eliminate parasitic modulation, which distorts the envelope of the output signal of the converter in a phase-sensitive mode, it is proposed to use an auto-shift circuit with a falling “slow” sawtooth voltage when generating gating radio pulses.
Packet method of data transmission in radar and radio navigation upper-air sounding systems
Authors: Plokhikh Oleg , Gusev Andrey , Kudinov Sergey , Shirshov Nicolay
Published: November 2019

The use of the packet method of transmission of coordinate- telemetry information to the ground station in radiosondes of upper-air sounding systems can significantly reduce the influence of interference arising in the radio channel, increase the reliability of receiving transmitted information, reduce the cost of measurements of meteorological parameters of the atmosphere on the scale of the aerological network of the Russian Federation.
Calculation of precipitation intensity using processing the sequence of video frames
Authors: Garmash Vitaliy , Zhdanov Alexander , Korobochkin Dmitriy , Petrov Yuriy , Yarigin Dmitriy
Published: November 2019

The article describes the method for automatic precipitation detection and its intensity estimation from a sequence of video frames. The convolution operation used for filtration is optimized in order to decrease computational complexity. The accuracy of precipitation intensity estimation is improved by accounting for cross-correlation between sequential video frames. The proposed method has reduced computational complexity. The results of the study are demonstrated on a few images of different size. The computational complexity of proposed algorithm is appropriate for real-time implementation.
Semi-automatic system for non-invasive diagnosis of bronchial asthma based on microwave technologies
Authors: Sememik Ivan V. , Dem’yanenko Alexander V. , Topalov Feruz S.
Published: November 2019

In this paper, the structure of a semi-automatic non-invasive harmless diagnostic system for bronchial asthma and other bronchopulmonary diseases are discussed. The components of the diagnostic system are discussed. It is shown that it is possible to design a diagnostic system in a portable compact design by using a laser displacement sensor instead of a bulky positioning system. The advantages of the proposed system are the simplicity of the implementation of the diagnostic system and examination, harmlessness, non-invasiveness of the examination procedure, no need to perform breathing maneuvers. These advantages allow us to consider the proposed system as an addition to the existing methods of diagnosing bronchial asthma, as well as an express method for diagnosing bronchopulmonary diseases or a system for periodically monitoring the health of a patient undergoing inpatient treatment or not having permanent access to a large medical center equipped with expensive equipment.
Numerical simulation of miniature antennas applicators of microwave radiometry for diagnostics of the functional state of the brain
Authors: Leushin Vitaly , Chizhikov Sergey , Vesnin Sergey , Sedankin Mikhail , Porokhov Igor , Gorbachev Dmitry , Goriacheva Evgenia
Published: November 2019

This paper describes the use of Finite Difference Time Domain technique of numerical modeling for development and simulation symmetrical dipole with triangular shoulders placed in a cylindrical housing and a spiral antenna placed in a cylindrical housing for use in microwave radiometry. The new sensors have been tested and validated on different phantoms and biological tissues. Results suggest sufficient characteristics of broadband antennas for potential use in brain functional diagnostics.