bluuebunny/crossref_metadata_2025 huggingface dataset:
Phase transitions, Dirac and WSM states in Mn1−xGexBi2Te4
Authors: Shikin A.M. , Zaitsev N.L. , Estyunina T.P. , Estyunin D.A. , Rybkin A.G. , Glazkova D.A. , Klimovskikh I.I. , Eryzhenkov A.V. , Kokh K.A. , Golyashov V.A. , Tereshchenko O.E. , Ideta S. , Miyai Y. , Iwata T. , Kosa T. , Kuroda K. , Shimada K. , Tarasov A.V.
Published: June 2024

Using angle-resolved photoemission spectroscopy (ARPES) and density functional theory (DFT), an experimental andtheoretical study of changes in the electronic structure (dispersion dependencies) and corresponding modification of the energyband gap at the Dirac point (DP) for topological insulator (TI) Mn1−xGexBi2Te4 have been carried out with gradual replacementof magnetic Mn atoms by non-magnetic Ge atoms when concentration of the latter was varied from 10% to 75%. It was shownthat when Ge concentration increases then the bulk band gap decreases and reaches zero plateau in the concentration range of45%–60% while non-topological surface states (TSS) are present and exhibit an energy splitting of 100 and 70 meV in differenttypes of measurements. It was also shown that TSS disappear from the measured band dispersions at a Ge concentrationof about 40%. DFT calculations of Mn1−xGexBi2Te4 band structure were carried out to identify the nature of observed banddispersion features and to analyze a possibility of magnetic Weyl semimetal state formation in this system. These calculationswere performed for both antiferromagnetic (AFM) and ferromagnetic (FM) ordering types while the spin-orbit coupling (SOC)strength was varied or a strain (compression or tension) along the c-axis was applied. Calculations show that two differentseries of topological phase transitions (TPTs) may be implemented in this system depending on the magnetic ordering. At AFMordering transition between TI and trivial insulator phase goes through the Dirac semimetal state, whereas for FM phase suchroute admits three intermediate states instead of one (TI — Dirac semimetal — Weyl semimetal — Dirac semimetal — trivialinsulator). Weyl points that form in FM system along the ΓZ direction annihilate when either the SOC strength decreases or asufficient tensile strain is applied, which is accompanied by the corresponding TPTs. Model calculations of local magneticordering influence in AFM Mn1−xGexBi2Te4 was carried out by alternating Mn layers and Ge-doped layers and showed that themagnetic Weyl semimetal state in this system is reachable at a Ge concentration of approximately 40% without application ofany external magnetic fields
Inverse initial value problem for space-time fractional diffusion equations
Authors: BenSalah Mohamed
Published: June 2024

This paper addresses an inverse problem associated with a space-time fractional diffusion equation, specifically focusing on the task of recovering the initial condition using additional final data. Through the application of the eigenfunction expansion method, we establish the well-posedness of this inverse problem in the Hadamard sense. Our analysis confirms the existence of a unique solution for the initial inverse problem and highlights the possibility of recovering the unknown term with Lipschitz stability. To further illustrate the effectiveness of our approach, we present several numerical examples that showcase its accuracy and efficiency.
2020 Mathematics Subject Classification: 34M50, 65M32, 26A33, 34A45.
The efficacy of a novel porcine-derived collagen membrane on guided bone regeneration: A comparative study in canine model
Authors: Nguyen Anh Thi Mai , Landao-Bassonga Euphemie , Kontogiorgos Elias D. , Lee Clair , Cheng Tak , Ngo Hien Chi , Allan Brent , Goonewardene Mithran , Opperman Lynne A. , Zheng Minghao
Published: June 2024

Background:This study aimed to evaluate the performance of the novel Striate+™ collagen membrane in a canine model of guided bone and tissue regeneration (GBR) with dental implant placement.
Methods:Eighteen mature beagle dogs were used in this split-mouth design study. After having their premolar extracted, immediate implants with GBR techniques were carried out on all study subjects. The study treatments were: control group (implant + no membrane); BG-group (implant + Bio-Gide® membrane); and SG-group (implant + Striate+™ membrane). Six dogs were sacrificed at 4-, 8- and, 12-weeks post-treatment for radiographic (μCT) assessment, histological examination and histomorphometric analysis.
Results: μCT assessment showed that all groups exhibited increased bone formation from 4-weeks to 12-weeks post-treatment. There was no statistically significant difference in mean BV/TV between all 3 groups at weeks 4 and 8. But at week 12, BV/TV was significantly higher in SG and BG-groups compared to control group. Assessment of bone microarchitectural parameters showed that animals in SG-group exhibited significantly higher Tb.N, O.Wi and lower Tb.Sp, suggesting more favorable mature bone structure. A significant increase in the number of osteoblasts on bone surface was also seen in SG-group. Histological assessment showed that SG-group displays early signs of bone-to-implant contact at 8 weeks. While control sites showed early ingrowth of epithelium and connective tissue into the defects, infiltration of inflammatory cells, incomplete bone formation and limited bone to implant contact; significant bone infill, mature bone with good implant contact and limited soft tissue invasion were observed in SG- and BG- groups.
Conclusion: This study demonstrated superiority of Striate+™ collagen membrane in GBR and prevention of unwanted epithelial infiltration in a canine model.
Laboratory evolutions lead to reproducible mutations in PDR3 conferring resistance to MCHM
Authors: Ayers Michael C. , Momtareen Taizina , Patriarcheas Dionysios , McCarthy Liam , Judge Daniel , Poziviak Seth , Leombruno Griffen , Quinn Makaela , Wonsettler Natalie , Lowery Camryn , McCulloch Sarah , Dale Nathan , Jonas Felix , Gallagher Jennifer E. G.
Published: June 2024

The solubility of protein complexes and membraneless compartments is maintained by liquid-liquid phase separation (LLPS). Phase transition is induced or dissolved by biological hydrotropes such as ATP and RNA. 4-methylcyclohexane methanol (MCHM), an alicyclic alcohol, is a synthetic hydrotrope that induces a starvation response by upregulation of biosynthetic pathways despite the availability of nutrients. To investigate how cellular metabolism can tolerate changes in LLPS, we evolved eight MHCM-resistant strains of S. cerevisiae. We identified thousands of SNPs and indel variants per strain, which was a consistent number between strains that evolved resistance and control strains that remained sensitive. These variants did not show a pattern that would cluster resistant strains together. The many background mutations likely masked any pattern from few large-effect loci or implicated an epistatic effect of many small mutations spread throughout the genome that was undetectable. Among coding variants in the strains that change protein sequence and thereby may alter function, only one gene showed a protein-coding mutation in every resistant strain while showing no variants at all in the control strains. This gene, PDR3, controls transcription for the pleiotropic drug response and is the most significant driver of adaptive MCHM resistance in yeast. While many of the evolved alleles of PDR3 would likely produce functional proteins, a knockout in the parent YJM789 strain was sufficient to produce resistance to MCHM. Normal catabolism of amino acids uses the Pleiotropic Drug Response (PDR) pathway to export breakdown products. The pdr3 resistance is mediated through Med15, a component of the Mediator complex which regulates activation by transcription factors of RNA pol II. Pdr3 can homodimerize or dimerize with Pdr1, another transcription factor and loss of Pdr1 also confers MCHM resistance. Knockouts of other mutated genes in flocculation, glutathione, SAM, and sugar transport mildly affected growth in the ancestral strain. Mutations in PDR3 are first known to increase resistance to this novel hydrotropic chemical.
Combined self-potential and electromagnetic imaging provides insights into the spatial variation of wetland soil hydro-biogeochemical properties
Authors: Doro Kennedy O. , Kolapkar Amar , Emmanuel Efemena Destiny
Published: June 2024

This study assesses the innovative use of self-potential (SP) combined with electromagnetic imaging and direct soil properties measurements for characterizing the distribution of wetland soil organic matter (SOM), soil moisture content (SMC), and redox potential (EH). SP distributions were measured using a high-impedance multimeter, Cu-CuSO4 non-polarizing electrodes, and a fixed reference electrode approach at two wetlands in northwest Ohio. The SP data were compared with laboratory measurements of SMC and SOM on 16 soil samples and 95 direct field measurements of EH and SMC. Soil apparent electrical conductivity (ECa) and magnetic susceptibility (MSa) were also acquired along co-located transects with the SP to assess the source strength of the SP and to aid the interpretation of the SP signals. Results of this study show variation in SP magnitude of up to 45 mV over 400 m in the wetlands. Negative SP anomalies were observed around areas with drainage tiles with preferential infiltration. The measured SP correlates with SOM, SMC, and EH, with R2 values of 0.67, 0.51, and 0.74. A combination of SP signals with soil electrical conductivity produced current density cross-sections, which provided information on the depth and intensity of the source charges generating the SP signals. Regions with high ECa and low SP signals show corresponding low MSa interpreted as anaerobic reducing zones. These results show the existence of natural potential gradients within wetland soils related to electrokinetic and electrochemical effects and validate SP as a useful complementary technique for characterizing wetland soils and monitoring their biogeochemical functioning.
A computational model of behavioral adaptation to solve the credit assignment problem
Authors: Clymer Roy , Namjoshi Sanjeev
Published: June 2024

The adaptive fitness of an organism in its ecological niche is highly reliant upon its ability to associate environmental or internal stimuli with behavioral responses through reinforcement. This simple but powerful approach has been successfully applied in computational neuroscience and reinforcement learning to model both human and animal behaviors. However, a critical challenge faced by these models is the credit assignment problem, in which the association between past behavior and a delayed reinforcement signal must be considered. In this paper, we reformulate the credit assignment problem to consider how past stimuli are linked to adaptive behavioral responses in a simple neuronal circuit. We propose a biologically plausible variant of a spiking neural network, which can model a wide variety of behavioral, learning, and evolutionary phenomena. Our model suggests one fundamental mechanism for associating a behavior with an adaptive response that may be used in the brains of both simple and complex organisms. Our results show the model's versatility and biological plausibility in a number of tasks related to classical and operant conditioning, including behavioral chaining. Additionally, we present simulations to demonstrate how adaptive behaviors such as reflexes and simple category detection may have evolved using our model. Our results indicate the potential for further modifications and extensions of our model to replicate more sophisticated and biologically plausible behavioral, learning, and intelligence phenomena found throughout the animal kingdom.
Neurokine fam19a5a/tafa5a regulates anxiety-like behaviors in zebrafish
Authors: Jeong Inyoung , Kim Seong Soon , Kim Hwan-Ki , Bae Myung Ae , Seong Jae Young , Park Hae-Chul
Published: June 2024

Anxiety refers to emotional responses triggered by discrete environmental factors that lead to defensive behaviors. Although the neural circuits underlying anxiety behaviors have been extensively studied, the molecular mechanisms involved in anxiety remain poorly understood. In this study, we explored the role of fam19a5a, a zebrafish ortholog of the human FAM19A5 gene encoding a secreted peptide, in anxiety responses. We conducted gene expression and behavioral analyses. Additionally, we measured the brain neuronal activity and analyzed the transcriptomes to elucidate the cellular and molecular mechanisms underlying the function of fam19a5a in anxiety-like responses. Gene expression analyses revealed a broad expression of zebrafish fam19a5a in anxiety-associated brain regions, including the septum, pallial amygdala, and habenula. Using multiple behavioral paradigms and genetic models for loss-of-function and gain-of-function studies, we demonstrated that loss of fam19a5asignificantly reduced anxiety-like behaviors, unlike those previously reported in Fam19a5 knockout mice. Moreover, neuronal overexpression of fam19a5a diminished anxiety-like responses. Neuronal activity analysis revealed altered activity in the septum, pallial amygdala, and habenula in the fam19a5a-knockout brain, without changes in neurotransmitter levels. However, elevated neuronal activity was observed in the preoptic area of the neuronal fam19a5a-overexpressing brain. Transcriptomic analyses revealed upregulation of anti-inflammatory chemokine/cytokine levels and downregulation of pro-inflammatory factor levels in both fam19a5a-knockout and neuronal fam19a5a-overexpressing brains. In summary, our findings suggest that fam19a5a regulates anxiety-like behaviors in zebrafish by modulating the anti-inflammatory chemokine/cytokine signaling pathways.
Impact of Momordica charantia Phytocompounds against AChE Associated with Neurodegenerative Diseases: In-silico Approaches.
Authors: Mohanty Sanjib Kumar , Nayak Yashaswi , Sahoo Lopamundra
Published: June 2024

The bioactive phyto-components of Momordica charantia L. demonstrate significant therapeutic potential against the acetylcholinesterase (AChE) enzyme, which is associated with neurodegenerative diseases such as Alzheimer’s. In this study, we utilized computational tools to screen the essential bioactive compounds of Momordica charantia L. against AChE. Docking results revealed that among the 19 phytocompounds analyzed, Ajmalacine, Alkaloid AQC2, Alkaloid SP-K, Steroid U, and quinine exhibited high binding affinities towards AChE. Ligand-protein binding interactions indicated that these selected compounds showed excellent interaction with AChE, with binding scores ranging from −11.0 kcal/mol to −9.1 kcal/mol. additionally, drug-likeness scores suggest that quinine and Steroid U are suitable as drug-like molecules. Our findings indicate that quinine and Steroid U have potential as therapeutic agents in the development of anti-AChE drugs for neurodegenerative diseases such as Alzheimer’s.
The Effect of Storage Time on the Levels of Phthalates in Extemporaneous Preparations in Ghana
Authors: Adu Abenaa Owusuwaa , Ayensu Isaac , Brobbey Abena Amponsaa , Bekoe Samuel Oppong , Azanu David , Boateng Joshua
Published: June 2024

The safety and quality of pharmaceutical products can be affected by chemical contaminants that migrate into them, depending on the type and composition of the packaging material. The migration of phthalates during manufacturing of plastics poses potential significant health concerns. This research aims to provide insight into factors driving phthalate migration and propose strategies for reducing its occurrence in extemporaneous preparations in Ashanti region, Ghana. Factors such as storage time and migration kinetics over two years were investigated to understand their impact on phthalate levels in Mist Senna Co (MSC), Mist Potassium Citrate (MPC), Mist Magnesium Trisilicate (MMT) and Mist Expectorant Sedative (MES). The samples were analysed using reverse phase – High Pressure Liquid Chromatography (RP-HPLC) with Photodiode array (PDA) detection. A gradient elution using acetonitrile and 0.1% formic acid at a detection wavelength of 235 nm and a flow rate of 1 mL/min was employed. As the storage time increased, the levels of the phthalates increased. The migration of phthalates was influenced by the duration the polyethylene terephthalate (PET) bottle was in contact with the content of the bottle. The highest migration rate per week for all the phthalates was observed in diethylhexyl phthalate with the highest level being 19 µg/L in MMT, 16 µg/L in MSC, 12 µg/L in MES and 8.3 µg/L in MPC. The finding emphasizes the significance of implementing optimized storage time in reducing phthalate exposure in extemporaneous preparations in Ghana. This study could contribute to enhancing the safety and quality of pharmaceutical products in Ghana.
Exploring the Relationship Between Physical Activity and Childhood Asthma: A Systematic Review, Meta-Analysis, and Subgroup Analysis
Authors: Alotaibi Nemer , Alotaibi Khalid , Alhabeeb Habeeb , alsulais shahad A , Rehman Naureen , Tahir Hasan Nawaz
Published: June 2024

Background
Childhood asthma is influenced by various factors, including lifestyle choices such as physical activity (PA). This study systematically reviewed and meta-analyzed the association between PA and childhood asthma, with subgroup analyses based on sex, socioeconomic status, parental education, and BMI.
Methods
This systematic review and meta-analysis examined the association between physical activity (PA) and childhood asthma across 22 studies, irrespective of geographic location. Searches were conducted in the Medline, CINAHL, Google Scholar, and Web of Science databases through manual searches. Quality assessment was performed using the Newcastle–Ottawa Scale (NOS) for cohort, case–control, and cross-sectional studies. Among the included studies, 17 were cross-sectional, 4 were cohort studies, and 1 was a case‒control study.
Results
The meta-analysis of cross-sectional studies revealed no significant association between physical activity and childhood asthma, with a pooled odds ratio (OR) of 1.07 (95% confidence interval [CI]: 0.84–1.36) and considerable heterogeneity (I2 = 82%). However, a cohort study demonstrated a significant association, with a pooled relative risk (RR) of 1.14 (95% CI: 1.11–1.17). Subgroup analysis revealed a significant association between low socioeconomic status (SES) and parental education and greater odds of asthma among children. All included studies were rated as moderate to good quality based on the Newcastle‒Ottawa Scale.
Conclusion
Although no overall association was found, targeted interventions promoting PA in children at higher asthma risk, especially those with low socioeconomic status, parental education, or BMI, could help mitigate the burden of asthma in childhood.
Study of Landslides in Greater Kabylia, « Tizi-Ouzou » Province: A Geophysical Approach with AHP Method
Authors: Belaid Lyes , ARAB Nabil amine , ARAB Mohamed
Published: June 2024

A landslide is a geological phenomenon where a mass of earth moves along a slope(wikipedia). It can be triggered by natural factors such as earthquakes, heavy rainfall, snowmelt, and erosion, as well as human activities like deforestation, construction on unstable slopes, mining, and excessive irrigation. The consequences of landslides include loss of human lives, property damage, and environmental disruptions(Germán Portillo, 2023)
According to a previous study conducted in the Tizi Ouzou province and corroborated by several press articles, the issue of landslides is recurrent, especially during rainy periods. No fewer than 39 out of 67 municipalities are affected by this geological phenomenon(Samy Y, 2021). These landslides occur on areas larger than 2 hectares. The seaside town of Tigzirt, located 39 km north of the province, has been impacted by multiple terrain instabilities in three distinct zones: the East zone, the Central zone, and the West zone(Nacira & Bachir, 2015b). More recently, the Amirouche Boulevard in Ain El Hammam, southeast of the province, was also threatened by a landslide, prompting the allocation of a financial package of 400 million Algerian dinars (DA) for demolition and the implementation of a reinforcement study(SAMIR LESLOUS, 2022). Unlike most landslide studies in the Tizi Ouzou province, which focus solely on precipitation and the geological and lithological structure of the terrain, we opted to use the Analytic Hierarchy Process (AHP) method. This approach considers multiple factors to generate a reliable and comprehensive landslide susceptibility map for Tizi-Ouzou
Our study does not consider the occurrence of rain showers, which represent an exceptional case. Instead, it focuses on the risk assessment of landslides under normal conditions and with regular precipitation. This is why we have chosen the factor of proximity to the hydrographic network.
Impact of Burnout and Job Satisfaction on Patient Care Quality: A Cross-Sectional Study Among Nurses in Acute Care Settings
Authors: OCANSEY JOSEPH , Nertey Joshua
Published: June 2024

Objectives: To examine the relationships between burnout, job satisfaction, patient care quality, and retention intentions among nurses and to analyze the demographic factors influencing these variables.Methods: A cross-sectional study was conducted with 400 nurses from various acute care settings, including wards, intensive care units (ICUs), and emergency departments, across multiple hospitals. The data were collected using validated scales on burnout (Maslach Burnout Inventory), patient care quality, job satisfaction, and retention intentions. Descriptive statistics, correlation analyses, multiple linear regression, and ANOVA were used for data analysis.Results: The sample consisted of 53.7% female and 46.3% male nurses, with a fairly even distribution of age and years of experience. The average burnout score was 45.2 (SD = 11.3), with a range of 30–80. The mean patient care quality rating was 4.3 (SD = 0.8). Burnout was negatively correlated with patient care quality (r = -0.45, p < 0.001) and job satisfaction (r = -0.28, p < 0.05). Regression analysis indicated that burnout (β = -0.32, p < 0.001) and job satisfaction (β = 0.45, p < 0.001) were significant predictors of patient care quality. ANOVA revealed significant differences in burnout scores by age group (F = 9.88, p < 0.001) and years of experience (F = 7.70, p < 0.001) but not by sex (F = 2.01, p = 0.156). Patient care quality differed significantly by age (F = 2.83, p = 0.038) and experience (F = 3.33, p = 0.020) but not by sex (F = 0.31, p = 0.578).Conclusions: Higher burnout is associated with lower patient care quality and job satisfaction. More experienced nurses reported lower burnout and higher patient care quality. These findings highlight the need for targeted interventions to reduce burnout and enhance job satisfaction, particularly for less experienced nurses.
The Role of Cerebellar-Cortical Connectivity in Modulating Attentional Abilities: Insight from Football Athletes
Authors: Wang Jian , Gao Siyu , Tian Junfu , Hao Hong , Zhou Chenglin
Published: June 2024

Neuroplasticity, a phenomenon present throughout the lifespan, is thought to be influenced by physical training. However, the relationship between neuroplastic differences and attentional abilities remains unclear. This study explored the differences in brain function and attentional abilities between professional football athletes and novices, and further investigated the relationship between the two. To address this question, we included 49 football athletes and 63 novices in our study, collecting data on resting-state functional connectivity and Attention Network Test (ANT). Behavioral results from the ANT indicated that football experts had superior orienting attention but weaker alerting functions compared to novices, with no difference in executive control attention. fMRI results revealed that football experts exhibited higher fractional Amplitude of Low-Frequency Fluctuations (fALFF) values in the bilateral anterior cerebellar lobes, bilateral insula, and left superior temporal gyrus. Functional connectivity analysis showed increased connectivity between the left anterior cerebellar lobe and various cortical regions, including the right supramarginal gyrus, left precuneus, left superior frontal gyrus, bilateral posterior cerebellar lobes, and bilateral precentral gyri in experts compared to novices. More importantly, in the expert group but not in novice group, functional connectivity differences significantly predicted attentional orienting scores. Graph theoretical analysis showed that experts exhibited higher betweenness centrality and node efficiency in the Cerebelum_3_R node. Our findings demonstrate that long-term professional football training significantly may affect neuroplasticity and attentional functions. Importantly, our analysis reveals a substantive connection between these two aspects, suggesting that the integration of neuroplastic and attentional changes is likely mediated by cerebellar-cortical connectivity.
Inclusive Green Growth Dataset for African Countries
Authors: Kwesi Isaac K. , Gbolonyo Emmanuel Y. , Ojong Nathanael
Published: June 2024

Tracking the progress of countries in inclusive green growth (IGG) is crucial for shaping effective sustainable development policies. However, comprehensive IGG data is often inaccessible. Accordingly, rigorous empirical contributions in this direction in the context of Africa remain sparse. To address this, we computed IGG scores for 22 African countries from 2000-2020. Our data reveal that only nine of these countries are achieving green and inclusive growth. This dataset equips researchers and institutions to assess IGG progress and identify pathways that African governments can leverage to promote sustainable development.
JEL Codes: O55; Q01
«Letters from Chernihiv Region» by I.L. Shrag as a source for the history of the zemstvo liberal movement in the North of the Left-Bank Ukraine (80s of the 19th century)
Authors: Kotelnytskyi Nazar
Published: June 2024

The article analyzes the public epistolary of the well-known representative of the Zemstvo liberal party of the Northern Left Bank – Ilya LudvigovichShrag. The author comes to the conclusion that «Letters from the Chernihiv region» by I. Shrag is a unique and important source from the history of the Zemstvo liberal movement in the north of Left Bank Ukraine in the 80s of the XIX century, which very eloquently testifies to the ideological and political imperatives of the opposition aristocratic front of the region. In the public epistolary of Ilya Ludvigovych, which was published on the pages of the famous Ukrainian almanac Pravda, a panorama of social life in the Chernihiv province during the Counter-Reforms of Emperor Alexander III is presented, as well as the evaluation judgments and characteristics of the famous liberal regarding the general atmosphere of changes that took place in the Russian Empire at this time. period. In his letters, I. Shrag very eloquently characterized the historical genesis of the reign of Emperor Alexander III, which, according to the actor, was directly connected with the history of the Great Moscow State; presented albeit subjective, but very vivid characteristics to the ruling persons of the Chernihiv province at that time from the circle of reactionary politicians, in particular the Chernihiv governor –O.Anastasyev, emphasizing the demoralizing role of such officials in the life of the province; in sufficient detail, using specific examples, highlighted the reasons for the fundamental and irreconcilable conflict between the members of the Zemstvo liberal party of northern Ukraine and the conservative bureaucracy and the administration of the governor; as a professional lawyer, I. Shrag carried out a legal analysis of the basic counter-reforms of Alexander III – Zemstvo, judicial and city, rightly pointing out the great degradation of the country and society, which these legislative acts caused.
Teaching, Learning, and Technology: A Planning Guide
Authors: Proctor Len
Published: June 2024

Teaching, Learning & Technology is a two part, interactive, multimedia kit that has been designed to guide teachers and administrators in planning how to use current technology to enhance classroom teaching and learning. Part one contains a step-by-step guide to planning. Part two contains a library of audio and visual examples that are used to illustrate the planning process in action. Collectively, parts one and two do an excellent job of presenting a model for planning and modeling how multimedia can be used to support learning about and implementing a planning process.
Codebase release r0.1 for PanScales
Authors: van Beekveld Melissa , Dasgupta Mrinal , El-Menoufi Basem Kamal , Ferrario Ravasio Silvia , Hamilton Keith , Helliwell Jack , Karlberg Alexander , Medves Rok , Monni Pier Francesco , Salam Gavin P. , Scyboz Ludovic , Soto-Ontoso Alba , Soyez Gregory , Verheyen Rob
Published: June 2024

In this article, we document version 0.1 of the PANSCALES code for parton shower simulations. With the help of a few examples, we discuss basic usage of the code, including tests of logarithmic accuracy of parton showers. We expose some of the numerical techniques underlying the logarithmic tests and include a description of how users can implement their own showers within the framework. Some of the simpler logarithmic tests can be performed in a few minutes on a modern laptop. As an early step towards phenomenology, we also outline some aspects of a preliminary interface to PYTHIA 8.3, for access to its hard matrix elements and its hadronisation modules.
Responsible Knowing in Partnering
Authors: Vidrin Ilya
Published: June 2024

How partners encounter each other plays a role in whether they will be able to sustain their interaction. How partners go about maintaining their interaction reveals features of their epistemological system, particularly with respect to factors like what they know, what they take to be relevant to the interpretation, and what they value. In this way, the value system (what partners want) and the epistemological system (what partners know) intersect. By focusing on the role of reasoning and understanding, I believe we stand to gain a clearer picture of how expectations about interactions inform the dynamics between partners. This, in turn, affords a picture of what partners can actually achieve in and through their connection. I am particularly interested in considering what features of interaction are necessary for maximizing the affordances of the partnership. I say this not as a utilitarian interested in maximizing good simpliciter, but as a social epistemologist thinking about the contingent goods that are present in relation (e.g. care). The epistemic picture assumes that there are things that are knowable in dancing together, while the ethical picture assumes that partners are responsible for the things they ought to know.
Questioning ‘Man’ in Joana Tischkau’s Colonastics: Black Feminist Identity Politics in Contemporary German Theater
Authors: Hölscher Stefan
Published: June 2024

In my contribution to this volume on Responsive Bodies I want to take a closer look at recent Black feminist identity politics in German theater in order to think about what the Caribbean philosopher Sylvia Wynter calls ‘Man.’ In this regard later in this text I will focus on the video clip series Colonastics (2020) by Joana Tischkau. I will do so in relation to the colonial roots of post-war racism in Germany, more precisely the time after its reunification in 1989. In front of this background my claim is that Afro-German feminist theater makers in the last couple of years have been responding to a certain white dominant culture in the country I am living in as a white German, where right-wing political parties like the Alternative für Deutschland (AfD) are getting stronger again right now unfortunately. The responsiveness corresponding with the aesthetic practices of the theater makers being discussed here questions, I am claiming with Wynter, ‘Man’ as a dominant genre of being human and thereby brings forth a true pluralization of German society.
Responsive Bodies: Towards an Ethics of Contemporary Dance
Authors: Schwan Alexander
Published: June 2024

Providing an introduction to six major contributions towards an ethics of contemporary dance, the text draws on the example of Anna Halprin’s Circle the Earth: Dancing with Life on the Line (1989) and raises the fundamental question: How does an ethical responsibility arise in the situation of a performance and extends beyond the moment of dancing and the experience of a dance piece? How can we understand contemporaneity beyond shared time and presence so that contemporary dance can acknowledge the fragility and incompleteness of the past and unlock the potentiality of the future? And how is this understanding of contemporaneity linked to ethical responsiveness in dance and dance reception?
30 Years of Kinase Inhibitors: A Historical Overview and some Brazilian Contributions
Authors: Pedreira Júlia , Laufer Stefan
Published: June 2024

The past 30 years have been transformative in the landscape of drug discovery, and certainly one of the most ground-breaking areas was kinase research. Since its start in the mid-1990s, kinase studies have reached notable hallmarks, ranging from the development of the first inhibitor, to innovative treatment options for a range of diseases. Today, kinases remain a pivotal protein class in drug discovery. Contemporarily, the Brazilian medicinal chemistry scene has also evolved, and followed up to such trends in the global landscape of research. Notably, the creation of the Summer School of Pharmaceutical and Medicinal Chemistry (EVQFM, in portuguese) in 1995, and its subsequent 30 consecutive editions, has raised the interest and knowledge of multiple generations in Brazil. This review aims to briefly outline the history of kinase inhibitor research, some of its landmarks, and highlight some of the contributions of Brazilian researchers to this important field of medicinal chemistry.
Advancements in the Synthesis and Biological Properties of Carboranes and High‑Boron Related Compounds: A Comprehensive Exploration with Emphasis on BNCT Applications
Authors: Couto Marcos , Cerecetto Hugo
Published: June 2024

Since Locher proposed the concept of boron neutron capture therapy (BNCT) in 1936, it has become a great challenge in the field of medicinal chemistry. The great dare has been to obtain boron-containing compounds that selectively accumulate in the organ to be irradiated. Polyhedral boron clusters (PBC) have been considered attractive moieties for the development of BNCT-agents due to their large contribution of boron per molecule. Various issues arose in the first efforts to develop PBC during the 1940-1950s that prevented their application in BNCT clinical trials, such as a lack of selectivity and low boron tumor-accumulation. Currently, the most studied PBC in BNCT are the icosahedral dicarba-closo-dodecaboranes (C2B10H12) commonly referred to carboranes and, to a lesser extent, their mono-anionic derivatives resulting from the loss of a B-vertex, commonly known as nido-carborane, and their metal complexes, known as metallacarboranes. This review will cover the medicinal chemistry of PBC for BNCT.
Barriers to people's participation in watershed intervention projects: perspectives of experts and local communities
Authors: Noor Hamzeh , Tabe Marzieh , Salehpour Jam Amin , Khaleghi Bagher
Published: June 2024

The present study aimed to identify and prioritize people's participation barriers (PPBs) in watershed intervention projects (WIPs), considering the perspectives of both experts and local people in the Dastgerd watershed, Iran. Thirteen important PPBs in the implementation of WIPs were identified in the study. The findings indicated that a lack of participatory guidelines, an expert-oriented decision-making process, and a deficiency in economic incentives during the implementation of WIPs constituted the most crucial PPBs. In addition, according to the two-sample KS test, there is a significant difference in the perspectives of the two groups regarding the importance of 60% of PPBs. The biggest differences were observed concerning the two barriers of `ignoring people's benefit from the project' and `lack of people consultation and attention to their suggestions'. Given the substantial impact of expert opinions on policy-making in watersheds, any misconceptions they hold regarding barriers and incentives for people's participation can lead to adverse outcomes in the planning of soil and water conservation projects. To address this issue, the establishment of think tanks and the facilitation of brainstorming sessions play a pivotal role in fostering mutual understanding, aligning the perspectives of local people and experts, and making informed decisions to overcome challenges.
Desarrollo de la inteligencia social: diseños curriculares, urbanidad y ruralidad
Authors: Lotero Franco Juan Camilo , Arroyave Taborda Leisy Magdali , Restrepo Segura Yusty Carolina
Published: June 2024

La investigación que se muestra en este artículo tuvo como propósito comprender los aportes de los diseños curriculares para el desarrollo de la inteligencia social en dos escenarios educativos (urbano y rural), por medio de un enfoque cualitativo. Para la recolección de la información se aplicaron entrevistas semiestructuradas a docentes y directivos. Se utilizaron dos técnicas interactivas (colcha de retazos y sociodrama) con los niños de primer a tercer grado de básica primaria. Los participantes de la investigación pertenecen al Centro Educativo Rural San Juan sede San Jorge (San Roque, Antioquia) y al Colegio Bautista de Castilla (Medellín). Los resultados permiten afirmar que, si bien existen modelos estándares en el diseño curricular de ambas zonas, su implementación se diferencia de forma notable. Así mismo, que las habilidades académicas son forjadas explícitamente dentro del currículo real, mientras que las habilidades sociales hacen parte del currículo oculto. Además, que la inteligencia social ha sido un tema implícito en la interacción entre docentes y estudiantes, pero no se han desarrollado contenidos específicos sobre este tema en el currículo formal. En conclusión, sería pertinente pensar en contenidos explícitos para el desarrollo de la inteligencia social, teniendo en cuenta las particularidades de cada contexto.
Aplicación móvil como recurso didáctico para el aprendizaje de las matemáticas financieras en el ámbito educativo
Authors: Carreño Flórez Edgar Farid , Palacios Alvarado Wlamyr , Medina Delgado Byron
Published: June 2024

El objetivo de la presente investigación fue desarrollar una aplicación móvil como un recurso interactivo y didáctico para los estudiantes del área de matemáticas financieras empleando como soporte la aleatoriedad del sistema con un enfoque de aprendizaje significativo. La investigación se efectuó mediante una óptica cualitativa-descriptiva en la que el diseño de la aplicación móvil provee un solucionario financiero previa selección del material de estudio y categorización en interés simple, compuesto, anualidades y gradientes. El aplicativo multimedia permite la clasificación y selección del material predispuesto en matemáticas financieras basado en la interacción por contenido y totalmente al azar a través del cual se asegura el trabajo equipo, la comunicación y el intercambio de saberes según el nivel resolutivo que pueda llegar alcanzar el estudiante. El modelo de estudio de las matemáticas financieras a partir del aplicativo móvil So.Mat.Fi está soportado en la captura de la atención del individuo en búsqueda de eludir la arbitrariedad y la ausencia de sustancialidad principales causas que influyen en la enseñanza significativa, lo que brinda la formación de modo ágil y sencillo de manera tal que los requerimientos del actual usuario de la cuarta revolución tecnológica puedan ser satisfechos.
Estructura y construcción de artículos científicos. Una revisión sistemática
Authors: Guzmán Brand Víctor Alfonso , Gelvez García Laura Esperanza
Published: June 2024

El objetivo del presente estudio es describir los aspectos estructurales y funcionales de la producción científica, específicamente en lo que respecta a los artículos científicos y su tipología, así como analizar cómo estos influyen en su difusión en diversas revistas académicas. Para alcanzar este propósito, se aplicó el método de revisión sistemática (PRISMA), empleando palabras clave y operadores booleanos, lo que permitió recopilar información a nivel nacional e internacional sobre esta temática. Además, se realizaron revisiones de libros, revistas y trabajos de investigación relacionados. El enfoque metodológico utilizado en este estudio es cualitativo y se basa en un análisis crítico de la información presente en la literatura publicada sobre esta temática. Es importante resaltar que la transferencia y socialización del conocimiento son aspectos esenciales para que los investigadores contribuyan al avance de la ciencia. La producción científica juega un papel crucial en la formación de comunidades de conocimiento; no obstante, la falta de comprensión sobre cómo comunicar los resultados de la investigación a través de artículos científicos, así como la escasa familiaridad con sus tipologías y estructuras de presentación, puede dar lugar al rechazo de muchas iniciativas por parte de revistas de alto prestigio.
Superación histórico-musical desde la obra de Laureano Fuentes Matons
Authors: Silva Santiago Iránea , Rodríguez Cosme Maria Luz , Marín Arias Olga
Published: June 2024

El conocimiento histórico-musical local es importante para los estudiantes de música, pues reafirma su sentido de identidad y pertenencia a la localidad. En ese orden de ideas, se propone valorar la vida y obra de Laureano Fuentes Matons, relevante compositor del siglo XIX en Santiago de Cuba, para sistematizarla en la enseñanza musical. Se tuvo en cuenta el enfoque cualitativo para utilizar el método de historias de vida, partiendo básicamente de la revisión y el análisis documental. Para dicho fin, resultaron imprescindibles sus obras (conservadas en escritura original) y la sistematización de los estudios acerca de este músico. Se le propone al docente de música una estrategia de superación histórico-musical, como proceso pedagógico, que promueva el conocimiento de la vida de este autor y el estudio de sus obras a partir de las transcripciones realizadas por la investigadora. Este estudio ha permitido exponer una visión poco conocida del artista a la luz de un análisis de sus obras en su contexto histórico, social y cultural, que se refleja a través de aspectos de la historia local y nacional. Sus composiciones constituyen un aporte al patrimonio histórico-musical cubano.
Análisis de las estrategias argumentativas utilizadas por el alumnado de secundaria en la resolución de tareas de generalización de patrones lineales
Authors: Pérez Rodríguez Oriol , De Gamboa Rojas Genaro , Badillo Jiménez Edelmira Rosa
Published: June 2024

El trabajo tiene como objetivo comparar las justificaciones que genera el alumnado de secundaria de 14 y 15 años en tareas de generalización de patrones lineales, relacionándolas con la manera de formular los enunciados. En el estudio se analizaron las estrategias argumentativas utilizadas por los alumnos cuando la estructura del enunciado varía utilizando dos cuestionarios; para ello, se analizaron las justificaciones escritas a las tareas en los cuestionarios y se identificaron perfiles resolutores de todo el alumnado para cada tarea en base a las estrategias argumentativas utilizadas. A continuación se comparan estos perfiles resolutores para cada alumno en los dos cuestionarios propuestos. Los resultados muestran que una parte del alumnado presenta diferencias significativas en las estrategias argumentativas que utilizan para resolver los dos cuestionarios. Se puede concluir que hay casos donde la estructura del enunciado es determinante para llegar a una respuesta correcta.
Análisis de los resultados Saber 11 (2020-2021) para fortalecer el proceso de enseñanza-aprendizaje en la era poscovid-19 - Lectura crítica
Authors: Guete García David Omar , Belmonte Jiménez Sandra Carolina
Published: June 2024

Este artículo presenta los resultados de una investigación que analizó los resultados de las pruebas Saber 11 de los estudiantes de la Institución Departamental Armando Estrada Flórez, ubicada en la zona rural del municipio de Zona Bananera, Magdalena, durante los años 2020 y 2021. El objetivo de la investigación fue identificar variables que permitan caracterizar a la población de estudio y mejorar el proceso de enseñanza aprendizaje en la institución. Para ello, se utilizó el banco de datos públicos de los desempeños individuales de Saber 11, publicadas por el Instituto Colombiano para la Evaluación de la Educación (ICFES). En este artículo se presentan los resultados de la prueba de Lectura Crítica, que contrastan los bajos desempeños obtenidos por la institución con los hallazgos a nivel nacional en época de pandemia. La lectura crítica es una de las áreas con mayor dificultad en el país.
La investigación educativa y su incidencia en los procesos educativos poscovid
Authors: Molina Isaza Liliana Esther
Published: June 2024

La investigación educativa busca conocer la realidad educativa, con el fin de reorientar los procesos educativos y visionar un futuro sostenible. Por tanto, el articulo tiene como objetivo central estudiar la incidencia de la investigación educativa en los procesos educativos poscovid. Para esto, se realizó un estudio documental utilizando la técnica de revisión de contenido, que da respuesta a tres cuestionamientos directores. Dentro de los resultados se destaca que son varios los paradigmas que sustentan la investigación educativa, y estos se fundamentan bajo los enfoques cualitativo, cuantitativo y la complementariedad de estos (mixto); los efectos de la pandemia en educación no son más que el resultado de problemáticas existentes, que se hicieron más profundas y evidentes y revelan el estado de descuido de la educación. Entre los principales aportes de la investigación educativa se destaca la documentación y producción científica sobre las consecuencias de la pandemia en modelos de aprendizaje y paradigmas educativos (ecosistemas digitales), y la reflexión de los entes involucrados en educación. La investigación educativa además plantea barreras, específicamente en la formación de nuevos investigadores y la comprensión de la relación entre episteme, paradigma y objeto epistémico del investigador, lo cual es necesario para entender los fenómenos educativos.
Finanzas para el futuro: la relevancia de la educación financiera en estudiantes de educación media
Authors: Molina Hurtado Yudy Alexandra , Arévalo Ruiz Yulieth Daniela , Bravo Maldonado Yeila Yuliana
Published: June 2024

La educación financiera es fundamental para manejar los recursos personales y tomar decisiones financieras acertadas. Lamentablemente, en la actualidad se descuida la enseñanza de esta materia desde edades tempranas en el sistema educativo. El propósito de la presente investigación es identificar el nivel de conocimiento financiero de los estudiantes de educación media en la Institución Educativa Francisco de Paula Santander, en Ventaquemada, Boyacá. Se utilizó un enfoque mixto de tipo analítico descriptivo en una muestra conformada por 184 alumnos pertenecientes a los grados décimo y once. Los datos se recopilaron mediante un cuestionario integral que abordó aspectos sociodemográficos y conceptos financieros como presupuestos, ahorro, inversión, ingresos y crédito. Los hallazgos indican que la mayoría de los participantes poseen un nivel básico de comprensión en temas financieros, influenciado en gran medida por la falta de capacitación en administración y planificación financiera de sus padres. Esta brecha en la formación persiste de generación en generación, especialmente en áreas rurales. Incorporar la educación financiera en etapas tempranas del currículo tiene el potencial de cambiar la comprensión de la economía personal y mejorar la toma de decisiones respaldadas por información eficaz y oportuna en un mundo económico que se vuelve cada vez más complejo.