bluuebunny/crossref_metadata_2025 huggingface dataset:
Information Security in E-Government: Legal Aspects
Authors: Politanskyi Viacheslav , Lukianov Dmytro , Ponomarova Hanna , Gyliaka Oleh
Published: July 2021

The article examines the characteristics of the functioning of information security in the e-government system, a phenomenon that is only possible based on the development of the information security infrastructure. The authors analyze information security as a key element of the concept of e-government, as well as various interpretations and ways of explaining the concept of information security. The research team's approach to the definition of the concept of information security is formed from the deep understanding of this concept, in terms of general theoretical analysis. Topics, objects, functions, types, principles, forms, levels of provision and structural elements of information security are studied. It is concluded that the organization of modern computer security of the State is undoubtedly a complex, systemic and multilevel phenomenon, whose state, dynamics, and perspectives are directly influenced by many external and internal factors, the most important being the political situation. In the world the presence of possible external and internal threats; state and level of development of information and communication of the country and internal political situation, among other aspects.
Correlation of civil legal principles and civil procedural in Ukrainian legislation
Authors: Safonchyk Oksana , Didenko Larysa , Denysiak Natalia
Published: July 2021

Civil legal and civil-procedural legal relations are one of the most significant categories in the science of civil and civil-procedural law, the relationship of which is not fully studied in science, so it is necessary to reveal the essence of their correlation and find differences between them. In the legal doctrine, there is a small number of works that would reveal the content of the relationship of such legal relations, the algorithm and criteria for their comparison are not fully developed, the scientific approaches to the separation of the criterion of their comparison are not revealed. In this regard, it is necessary to fulfil the doctrinal study of civil legal and civil procedural legal relations, both separately and jointly, using a particular criterion. The following methods were used in the study of the relationship between civil legal and civil-procedural legal relations: formal-legal, generalization, method of analysis of normative documents, articles and monographs, comparative legal method. As a result of the research, the connections between such categories as civil legal relations and civil procedural legal relations were clarified, and the criteria for their comparison were singled out.
Features of the investigation of hooliganism committed by football fans
Authors: Boiarov Viktor , Larkin Mikhail , Kyrychenko Oleh , Penkov Sergey , Kruhlov Oleh
Published: July 2021

The article is devoted to the analysis of some features of the investigation of football hooliganism. The current state and trends of football hooliganism are considered (including during the COVID-19 pandemic). The main problems faced by the investigation authorities during the detection and investigation of football hooliganism have been identified. In the process of working on the article, the scientific literature on informal youth groups, the fight against extremism, the investigation of group crimes of football fans was analyzed. The purpose of the study is to identify and study the features of the investigation of hooliganism committed by football fans. The object of research is the peculiarities of the investigation of hooliganism committed by football fans. During the writing of the article, the following methods were used: observation, analysis, synthesis, comparison, generalization, extrapolation, modeling, and information approach. As a result of the conducted research, the modern tendencies of football hooliganism are defined. Emphasis is placed on the peculiarities of the transformation of football fans. The principal problems of detection and investigation of football hooliganism are outlined, recommendations for prevention and counteraction to crimes committed by football fans are developed.
Digitization in Law: International-Legal Aspect
Authors: Panova Liydmyla , Radchenko Liliya , Gramatskyy Ernest , Kodynets Anatolii , Pohrebniak Stanislav
Published: July 2021

Due to the development of the information society, countries face the task of effectively regulating the relevant social relations. The mechanisms of such regulation should correspond to the specifics of such relations. Digitization is one of the modern methods of legal regulation, which is the use of information technology at the state level. The existing scientific achievements on digitalization processes need constant improvement, which corresponds to the specifics of this field. The object of research is digitalization in law in the light of international experience. The article aims to study and analyze digitalization in law in the international legal aspect. The following methods were used during the study: systemic, systemic-functional, comparative, sociological, analysis, synthesis, analogy, observation, classification, and statistical analysis. The article analyzes the phenomenon of digitalization, identifies the main approaches to understanding it. On the example of international experience (such countries as France, Germany, Italy, Georgia, Greece, and Great Britain), the mechanisms of using digitalization in public administration are determined, the legal regulation of informatization is analyzed. Also, based on the study and analysis of doctrinal teachings of international information experience, it is proposed to improve the domestic legal mechanism to ensure the effective functioning of public relations.
Socio-Economic Foundations of Trump's Domestic Policy and The Globalist Project in The United States (2016-2020)
Authors: Kolomyts Dmitry , Vagapova Firdaus , Vagapov Renat , Ustinkin Segei , Kuvakova Irina , Morozova Natalia
Published: July 2021

The article considers the socio-economic dimension of former President Donald John Trump's domestic policy concept in the United States during his presidency from 2016 to 2020. The contradictions between D. Trump's policies and the concept of globalism stand out. During his domestic policy course, D. Trump sought to regain the ability of U.S. leadership to rebuild the country's big industry to achieve the independence of transnational financial capital. His policies had been partially successful and had created the conditions for a redefinition of the concept of globalism. Methodologically, the research, in reviewing Trump's globalist strategy and economic strategy, adopted a socio-economic approach to politics that simultaneously explored geoeconomics and geopolitical issues in their dialectical interactions, including on the socio-economic dimension itself. It concludes that the U.S. elite faced the need to accommodate the interests of the American population, whether Republican or Democrat. Moreover, as asocial phenomenon, Trumpism has shown that the politics of globalism has entered a period of conceptual and resource crisis characterized by its inability to consider the interests of the American population.
Regulation of advocacy profession: global trends
Authors: Vilchyk Tetiana , Sokolova Alla , Demchyna Tetiana
Published: July 2021

The objective of the article is to analyze the regulation of the legal profession and its global trends. There are many different types of regulators globally, and many different sources and methods of regulation. There is no simple approach to setting goals for regulating the legal profession in different legal systems. Although self-regulation of the legal profession is considered the basis for adhering to the standard of its independence, at the same time, academics recognize the existence of the theory of the management of the legal profession. To study these problems, the authors conducted a comparative study of the regulatory models of the legal profession in the world in terms of compliance with international standards of legal independence in different legal jurisdictions and made some suggestions to improve the legal regulation of the legal profession in Ukraine. Empirical sources for scientific research were international documents, court decisions, national legislation of Great Britain, Canada, the United States, Ireland, Scotland, Australia and others, and the work of scientists. The article uses general scientific methods - dialectic, analysis, synthesis, analogy, etc., and special methods, particularly legal, historical, and formal comparative law.
The role of the factors determining national character in building civil society
Authors: Komnatnyi Serhii O. , Sheremet Oleg S. , Suslykov Viacheslav E. , Lisova Kateryna S. , Svorak Stepan D.
Published: July 2021

The article deals with the mechanism of impact of sociopsychological phenomena such as the national character and the political mentality in the construction and functioning of civil society. It aims to show the impact of climate, religion, and the perception of happiness on the state of civil society through details of a national nature. The main research method is to compare data from global research on the state of civil society with data from climatic conditions, dominant religions, and happiness indices. The article proves coincidently that these factors are reflected in such essential characteristics of civil society as "openness" and "closed-mindedness". The interaction between the national character and the construction of civil society has two stages. It is concluded that the results obtained are important to evaluate the prospects for the construction and development of civil society in different countries and regions of the world. Further research in this direction involves the study of other aspects of the impact of national character and political mindset on the functioning of civil society.
To Study the Formation and Increase of Social Capital in Islamic Republic of Iran
Authors: Dinarvand Ali Abas , Azin Ahmad , Golshani Alireza
Published: July 2021

In the era of the Islamic Revolution and later the traditional networks and connections available in Iran that were generally religious, such as: mosques, tekyehs (place of Shia mourning for Imam Hussein), religious boards and seminaries, along with also religious values and norms in society a particular form of social capital was created. The main objective of the study is to analyze the formation and increase of social capital in the Islamic Republic of Iran. To achieve this objective, descriptive and documentary data collection methods are used. The collected materials are then categorized and used using the tab technique to obtain considered results. Based on the results obtained, it can be concluded that the existing traditional networks in Iran that continued to the farthest reaches of Iran, religious norms are mentioned as effective factors in the creation and increase of social capital and a factor of confidence-building between social and religious leaders.
Service learning in pharmacy: An effective pedagogical approach to undergraduate education
Authors: Rafferty Rebecca , Williams Emma , Willis Sarah C , Allison David G
Published: July 2021

Master of Pharmacy (MPharm) students at the University of Manchester experience service learning during the third year of the course. The students put their academic learning into practice and develop many professional skills whilst teaching and enthusing local high school pupils about various public health topics. This article explores how this example of service learning helps prepare the next generation of pharmacists for their future roles and summarises the practical aspects of the project and its success.
A cross-sectional study on Bangladeshi students regarding physiological challenges of online education
Authors: Shahriar Saimon , Koly Fahima Jannat
Published: July 2021

Introduction: The COVID-19 pandemic halted educational institutions all over the world which forced a shift to online classes, a new experience for Bangladeshi students which increased their screen time.
Objective: This study aimed at discerning the physiological challenges accompanied by the online education system and the compatibility of Bangladeshi students considering health and socio-demographic factors.
Methods: A cross-sectional pilot study was performed based upon an online survey on students (n = 590) during September 1st to 14th of 2020.
Results: Interestingly, an inevitable consequence of online education was several physiological problems. It was found that 93.9% of the participants faced some kind of physiological challenges, e.g., headaches, fatigue, eye and ear problems, from online classes. The majority of the participants (57.5%) could not concentrate for one hour or more in online classes.
Conclusion: Along with transitioning towards online education, innovative teaching methods would be helpful for the students to adapt to the ‘new normal’.
Drama del pensamiento y ocaso de la función “meta” de la metafísica
Authors: Palma Ramírez Manuel
Published: July 2021

El prefijo “meta” de la palabra metafísica dota a la filosofía primera de un dinamismo que se pone de manifiesto cuando, a partir de él, se presentan sus dimensiones metastáticas, metafóricas, metamorfósicas y metanoicas. De este modo, el pensamiento, todo él, está llamado a ser “auténticamente metafísico”, esto es, a sobrepasar el ámbito de los fenómenos y a alcanzar el fundamento de la realidad misma.
Computer Forensic Using Photorec for Secure Data Recovery Between Storage Media: a Proof of Concept
Authors: Pratama I Putu Agus Eka
Published: July 2021

Data plays the important role, so that data recovery and data security be prioritized. Computer users often lose their data due to personal errors or by attacks. Digital forensics has one sub-field called computer forensic, which has an important role in the process of secure data recovery. USB Flashdisk as the most widely used storage media has a probability of data loss. It is necessary to do computer forensic actions, especially secure data recovery, on it so that it can restore data securely to other media while protecting it by giving privilege root. In this research, computer forensic testing the 2781 files of various data formats that were erased on a 32 GB USB flash drive using Photorec. The media for collecting data recovery results using an Intel computer, 2 GB RAM, 1.8 GHz processor, the Linux operating system Xubuntu 20.04. Testing is carried out following the test scenarios that have been designed, then observed, recorded, and analyzed. Photorec places recovery data in 6 recup_dir subdirectories. Test results and analysis of the test results show that Photorec is a reliable tool for computer forensic, especially secure data recovery because it can restore 100% of data, accompanied by privilege root for all data recovery results, so they cannot be changed and deleted by an end-user without granted access.
Determinants of the Quality Financial Information Small and Medium Enterprises Sector
Authors: Eddy sarwono Aris , Asih Handayani
Published: July 2021

This study aims to determine the effect of owner support, personal technical skills, training and education programs, age, gender, length of business and formal education on the performance of accounting information systems. This research was conducted on Small and Medium Enterprises (SMEs) in the Solo Raya area. The type of data used is quantitative data. The data source used is primary data. Data collection techniques using a questionnaire. The population in this study is SMEs in the Solo Raya area. The sampling technique used purposive sampling method with the number of samples determined with a specific purpose as many as 56 SMEs. The results showed that the variables of owner support, personal technical ability, training and education programs had an effect on the performance of the accounting information system, while variables of age, gender, length of business and formal education had no effect on the performance of the accounting information system.
Utilization Of Glycerol By Product From Transesterification Of Waste Cooking Oil As A Cosurfactant In Nanocream Preparation
Authors: Rani Zulmai , Julia Reveny  , Urip Harahap
Published: July 2021

Waste cooking oil (used cooking oil ) is oil derived from leftover cooking oil for frying food. Waste cooking oil is still considered as waste by some people and waste cooking oil that should not be suitable for consumption is sometimes still widely reused in food processing, this can endanger health and reduce the nutritional value of food. In order to be used and have economic value, it is overcome by synthesizing waste cooking oil into glycerol so it can be used as cosurfactant. Besides as cosurfactant, this waste cooking oil glycerol also can be used for various chemical industies, foods, cosmetics, and pharmaceuticals industries. For cosmetic preparation, it can make a nanocream preparation. The purpose of this research was to utilize waste cooking oil into a glycerol which is used as a cosurfactant, to characterize the synthesis results based on IR Spectroscopy data and to formulate it to nanocream preparation. The research was conducted in an experimentally by making glycerol from side product of waste cooking oil. Separating glycerol process conducted by transesterification reaction. Glycerol of waste cooking oil by product was characterized with IR Spectroscopy and evaluated include organoleptic, glycerol contents, density, viscosity, ash content, and moisture content. Formulation of nanocream preparation using 30% of Tween 80 as surfactant, glycerol by-product as cosurfactant 7,5% concentration, and 20% of VCO as oil phase. The nanocream preparation was measured for its particle size with the aim of being able to determine the particle size of the formula to form nanoparticle size. The results showed that glycerol of waste cooking oil by product shows the presence of OH, CH-aliphatic, C=O carbonyl and C-O. particle size of nanocream preparation obtained was 397,76 nm. Based on the result of this research, the conclusion is glycerol of waste cooking oil  by-product can form nano size with presence of glycerol as cosurfactant. The particle size of the nanocream preparation obtained was still in the nanocream requirement range, namely 20-500 nm.
The Effect of Financing and Operational Income on Profit Sharing Return on Mudharabah Deposits for Islamic Commercial Banks
Authors: Faulia Anggeraini  , Inda Arfa Syera
Published: July 2021

The purpose of this study is to determine the effect of financing and operating income on the return for the results of mudharabah deposits in Islamic commercial banks. The stages of the research method used are the research approach, population and sample, operational definitions, types and sources of data, data collection techniques, data analysis, location and time of research as well as tools and materials. Based on the conclusions found in this study, there is a significant influence of financing variables and operating income variables on the return for the results of Islamic Commercial Bank mudharabah deposits, this is evidenced by the results of research conducted by researchers where the significance value (sig) of 0.001 is smaller than the probability of 0.05 , so it can be concluded that H0 is rejected and Ha is accepted, which means that there is an influence of financing and operating income on the return on profit sharing from mudharabah deposits of Islamic Commercial Banks.
ULOGA METAFORA U TEKSTOVIMA PUBLICISTIČKOG STILA – DISKURS O NATO BOMBARDOVANjU SRJ 1999. GODINE
Authors:   University of Kragujevac, Faculty of Philology and Arts, Vujošević Anđela
Published: July 2021

In der Arbeit werden Metaphern und ihre Bedeutung in journalistischen Texten in der serbischen Presse analysiert. Das Korpus besteht aus Online- Artikeln in der Tageszeitung POLITIKA, die sich mit den NATO-Bombenangriffen auf die Bundesrepublik Jugoslawien im Jahr 1999 beschäftigen. Ausgehend von der Theorie der konzeptuellen Metapher von G. Lakoff und М. Johnson bezieht sich die Arbeit auf neuere theoretische Modelle für Metaphern und ihre Rolle in politischen Diskursen und versucht zu zeigen, dass Metaphern kein stilistisches Mittel in einem literarischen Text sind, sondern die wichtigsten verbalen Mittel darstellen, mit denen abstrakte Konzepte wie Ideologien, soziale Prozesse, Emotionen oder kognitive Konzepte erklärt und angenähert werden können. Zusätzlich zu dieser grundlegenden Rolle sind Metaphern zur Entwicklung einer persuasiven und manipulativen Funktion in Massenmediendiskursen geeignet. Deshalb spielen sie in politischen Diskursen eine Schlüsselrolle, denn die gesamte politische und soziale Welt basiert auf vom Menschen geschaffenen Konzepten in abstrakten Bereichen, für die es in Wirklichkeit in der Regel keine konkreten Konzepte gibt. Das Verständnis dieser abstrakten Konzepte findet also in den Bereichen der Metaphern statt.
Techniques to Determine Powder Flow Properties
Authors: Sharma Shaveta , Sharma Teenu , Deep Mahak , Sharma Ashima
Published: July 2021

The goal of the current work was to do an orderly assessment of flow of powders and granules using compendial and non-compendial procedure. Angle of repose, Tapped density, Carr's compressibility file, Bulk density, Hausner’s ratios were assessed. Moreover, flow was described utilizing powder rheometer wherein delicate force transducer screens the forces created as consequence of the sample displacement, another technique FT4 powder rheometer. The Freeman Technology (FT4 powder rheometer) is intended to describe powders undergoing different circumstances in manners that look like wide scale creation climate. Techniques incorporate security and irregular flow rate, compressibility, shear cell, air circulation, porousness, divider contact and union. The FT4 has demonstrated application on the whole powders preparing ventures, including drugs, fine synthetic substances, cosmetics, food, additives and powder covering. The FT4 application connect to filling, hopper flow, Tablet pressure, wet granulation, end point, flow added substance determination and enhancement, moisture impacts, static change, feeding, stirring, separation, caking, processing, Wall grating, grip, hopper configuration etc.
XIX. Yüzyıldan Günümüze Kadar Filibe'de Türkçe Basın
Authors: BEKİR Harun
Published: July 2021

Filibe (Plovdiv) şehri, geçmişten getirdiği kültürel zenginliği korumaktadır. Bulgaristan'ın ikinci büyük şehri olan bu bölge, önemli bir eğitim ve kültür kenti olarak varlığını sürdürmektedir. Burada birçok Türkçe gazete de yayımlanmaktadır. Bu araştırmanın amacı Filibe’de yayımlanan Türkçe gazete ve dergileri tespit edip Bulgaristan Türk basın tarihi açısından önemini belirlemektir. Betimsel tarama yöntemi kullanarak konuyla ilgili kaynaklar incelenmiş, Filibe şehrinde çıkmış olan gazete ve dergiler tespit edilmeye çalışılmıştır. Amacımıza ulaşmak için de Sofya’daki Aziz Kiril ve Metodiy Millî Kütüphanesi ile Filibe İvan Vazov Halk Kütüphanesi arşivlerindeki birincil kaynaklardan yararlanılmış, gazete ve dergilerin yayın süreleri ile yayın politikası incelenmiştir. Araştırma sonucu Filibe’de 41 süreli yayın belirlenmiştir. Bunların otuz sekizi gazete, üçü dergidir. Tüm bu bilgilere baktığımızda Filibe'nin Türk basın tarihi içerisinde önemli bir yeri olduğu aşikârdır.
Âşık Çelebi’nin Meşâ’irü’ş-Şu’arâ Tezkiresinde Balkan Şehirleri
Authors: ÇINARCI Mehmet Nuri
Published: July 2021

XVI. yüzyılda daha çok şairler tezkiresiyle bilinen Âşık Çelebi, küçük yaştan itibaren devrin büyük âlimlerinden eğitim almış ve hem anne hem de baba tarafından nam sahibi ailelere mensup şahsiyetlerden biridir. Tezkireciliğinin yanı sıra kaleme aldığı şiirleriyle şairliğinden de söz ettiren Âşık Çelebi, Balkanların önemli şehirlerinden birisi olan Prizren’e bağlı Vılçıtrın adında bir köyde doğmuştur. Eğitim hayatının önemli bir bölümünü İstanbul’da geçiren Âşık Çelebi, akabinde Osmanlı bürokratik yapısı içerinde üstlenmiş olduğu devlet memuriyetlerinin önemli bir kısmını Balkan sınırları içerisinde bulunan çeşitli şehirlerde icra etmiştir. Üstlenmiş olduğu görevler vesilesiyle bazı Balkan şehirlerinde yerleşerek oralarda uzun müddet yaşamış; tabi bu esnada tezkiresinde ifade ettiği kadarıyla yakın şehirlere seyahat etme fırsatı bulmuştur. Bu nedenle Âşık Çelebi’nin şairler tezkiresi olan Meşâ’irü’ş-Şu’arâ’da tezkirecinin görevi sebebiyle bulunduğu ya da gezmiş olduğu Balkan şehirleri ile ilgili edindiği çeşitli izlenimlere rastlamak mümkündür. Tezkirede bu şehirler kimi zaman fiziksel özellikleriyle ön plana çıkarken kimi zamanda sosyo-kültürel yapıları veya şairin ruhunda uyandırdığı güzel hisler bakımından tezkireye konu olmuşlardır. Bazı şehirler çeşitli yönleriyle ayrıntılı bir şekilde anlatılırken kimi şehirlere ise belli sebeplerden dolayı sadece değinilmiştir. Bu çalışmada Âşık Çelebi’nin şairler tezkiresi olan Meşâ’irü’ş-Şu’arâ adlı tezkiresinde çeşitli vesilelerle değindiği Balkan şehirleri ile ilgili malumat tezkiredeki örneklerden hareketle verilmeye çalışılacaktır.
Assessment of Antimicrobial, Antioxidant, Anti-inflammatory, and Anticancer Properties of Polyphenols in Ragi Plant
Authors:   Dayananda Sagar college of Engineering (Visvesvaraya Technological University), Kumarswamy layout, Bangalore-560078, India, Ramesh Vikil , Mathur Megha ,   Dayananda Sagar college of Engineering (Visvesvaraya Technological University), Kumarswamy layout, Bangalore-560078, India, S Kiran ,   Dayananda Sagar college of Engineering (Visvesvaraya Technological University), Kumarswamy layout, Bangalore-560078, India, N Rajeswari ,   Dayananda Sagar college of Engineering (Visvesvaraya Technological University), Kumarswamy layout, Bangalore-560078, India, Tidke Shashank A ,   Dayananda Sagar college of Engineering (Visvesvaraya Technological University), Kumarswamy layout, Bangalore-560078, India
Published: July 2021

Background and Objectives: (Eleusine coracana) is a rich source of proteins, phytochemicals, and fibers with several health benefits. Cancer accounts for 12c/o of death worldwide, which requires superior therapeutic strategies. Polyphenols are a class of phytochemicals in plant derived compounds, that has been reported to exhibit anticancer, antioxidant, anti-inflammatory and antimicrobial properties. The objective was to investigate the binding potential of selected polyphenols against probable drug targets of various types of cancer and provide an insight on the anti-inflammatory, antioxidant, and antimicrobial properties by using molecular docking method. Materials and Methods: Ten receptors were analyzed for anticancer, two receptors for anti- inflammatory, three receptors for antioxidant, and five receptors for antimicrobial studies. The binding competences of polyphenol towards selected targets were studied by molecular docking. Results: Affinity of polyphenols as an anticancer agent with respect specific targets viz CDKN1A, FOXO1, FGFR2, CTNNB1, and GST-PI was evident. The binding energies of docked complexes were found to be -116.56, -114.5, -110.38, -106.9, and -105.07 kcal/mol, respectively. In case of anti-inflammatory the best binding was seen in between COX-2 receptor with and COX-1 receptors. Antioxidant studies it was observed that SOD2 showed the best binding energy followed by SOD3. Followed by antimicrobial studies the best binding interaction some how were shown by IARS and PBP1a receptors. Conclusion: Present studies revealed that polyphenols has superior interacting properties towards these cancer targets than their normal ligands and shows a strong approach to anti-inflammatory, antioxidant, and antimicrobial activity
A 11 Week’s Gestation Ruptured Tubal Ectopic Pregnancy : A Case Report
Authors:   Department of Pathology, maternity and Children’s Hospital Ibn Sina University Hospital, Rabat, Morocco, Sabrine Derqaoui , Salma EL Majoudi ,   Department of Pathology, maternity and Children’s Hospital Ibn Sina University Hospital, Rabat, Morocco, Lamia Rouas ,   Department of Pathology, maternity and Children’s Hospital Ibn Sina University Hospital, Rabat, Morocco, Najat Lamalmi ,   Department of Pathology, maternity and Children’s Hospital Ibn Sina University Hospital, Rabat, Morocco
Published: July 2021

Background and Objectives: (Eleusine coracana) is a rich source of proteins, phytochemicals, and fibers with several health benefits. Cancer accounts for 12c/o of death worldwide, which requires superior therapeutic strategies. Polyphenols are a class of phytochemicals in plant derived compounds, that has been reported to exhibit anticancer, antioxidant, anti-inflammatory and antimicrobial properties. The objective was to investigate the binding potential of selected polyphenols against probable drug targets of various types of cancer and provide an insight on the anti-inflammatory, antioxidant, and antimicrobial properties by using molecular docking method. Materials and Methods: Ten receptors were analyzed for anticancer, two receptors for anti- inflammatory, three receptors for antioxidant, and five receptors for antimicrobial studies. The binding competences of polyphenol towards selected targets were studied by molecular docking. Results: Affinity of polyphenols as an anticancer agent with respect specific targets viz CDKN1A, FOXO1, FGFR2, CTNNB1, and GST-PI was evident. The binding energies of docked complexes were found to be -116.56, -114.5, -110.38, -106.9, and -105.07 kcal/mol, respectively. In case of anti-inflammatory the best binding was seen in between COX-2 receptor with and COX-1 receptors. Antioxidant studies it was observed that SOD2 showed the best binding energy followed by SOD3. Followed by antimicrobial studies the best binding interaction some how were shown by IARS and PBP1a receptors. Conclusion: Present studies revealed that polyphenols has superior interacting properties towards these cancer targets than their normal ligands and shows a strong approach to anti-inflammatory, antioxidant, and antimicrobial activity
Review of Mathematical Modelling Techniques in Breast Cancer Dynamics
Authors:   Department of Applied Mathematics and Statistics, Midlands State University, Maxwell Mashasha , Esther Chigidi ,   Department of Applied Mathematics and Statistics, Midlands State University
Published: July 2021

Cancer is an age related autoimmune disease initiated by genetic mutations leading to increased proliferation rate and tumor formation. Accumulation of various genetic and epigenetic changes, in normal cells gives cancer cells a selective advantage over healthy cells, and lead to cancer initiation and progression. Interactions of tumor cells with other cells within their reach, the microenvironment, is an important component in carcinogenesis. Its treatment is based on our level of understanding of its biology. Breast cancer is a collection of complex and heterogeneous diseases with distinct histopathological features. It arises due to abnormal growths of the cells lining the breast lobules hence men and women can develop it, although very rare in men (less than ). There are different types of breast cancer, and the most common are the invasive and non-invasive cancers. Usually, it is common to study breast cancer tumors as isolated entities, but its biological and molecular structure are indicative of an unstable heterogeneous disease with multiple subtypes coexisting within a tumor. Many studies with different methodologies have been carried out to understand cancer development and progression, however, another approach of mathematical oncology has emerged. This approach uses mathematical and computational techniques to unpack generation, growth and evolution of cancer cells. With this work we would like to review what has been done by others so as to improve our understanding of cancer dynamics
Immunostimulatory CpG Oligonucleotides as an Adjuvant with Recombinant DNA Vaccine Encoding Hepatitis C Virus Core Protein
Authors:   Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran, Karami Ali
Published: July 2021

The immunogenicity and protective efficacy of DNA vaccines have been amply demonstrated in numerous animal models against infectious diseases. In order to increase the potency of DNA vaccines, we have compared the immune response of conventional adjuvants such as aluminum phosphates, Dendrosome, CpG motif and mixture of aluminum phosphate and CpG motif. Female BALB/c mice were immunized with 10, 25 and 50 microgram of HCV core pcDNA3 plasmid mixed with the adjuvants. Each dose of recombinant pcDNA3 and different adjuvant were used as an immunogen in three IM injection periods. Blood samples were collected at four different times. The data indicate that the antibody response achieved following DNA immunization can be enhanced by CpG motif as molecular adjuvant
Lemierre’s Syndrome: A Complication of Cervicofacial Cellulitis in a Child
Authors:   Resident physician in otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco, GLITI Mohamed Ali , Messaoudi Lina EL ,   Resident physician in otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco, Nitassi Sophia ,   Professor of otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco, Razika Bencheikh ,   Professor of otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco, Anas Benbouzid Mohamed ,   Professor of otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco, Oujila Abdelilah ,   Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco, Houssyni Leila Essakalli ,   Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco
Published: July 2021

Introduction: Lemierre’s syndrome complicates oropharyngeal infection and associates septic thrombophlebitis of the internal jugular vein with sepsis and distant septic emboli (especially pulmonary). We report a pediatric case with thrombophlebitis of the jugular vein in the context of cervicofacial cellulitis. Summary of the Clinical Case: A 2-year-old girl consulted in the emergency room for angina complicated by right cervicofacial cellulitis with thrombosis of the right jugular vein. The diagnosis of atypical Lemierre syndrome was made and the patient received first medical treatment (antibiotic therapy, anticoagulation) allowing a cure without sequelae. And secondary surgical treatment (adenoidectomy and tonsillectomy). Discussion: The presence of a cervical venous thrombosis complicating an oropharyngeal infection should lead to a search for Lemierre’s syndrome (blood cultures and chest CT) rare but serious and require immediate treatment
Complementry Role of Bone Marrow Aspiration and Biopsy
Authors:   Tutor, Medical College, Baroda, Shah Nirali , Shah Vidhi ,   2nd M.B.B.S. student, Medical College, Baroda, Goswami Falguni ,   Tutor, Medical College, Baroda, Gidwani Roopam ,   Assistant Professor , Medical College, Baroda
Published: July 2021

Introduction: Bone marrow examination is an important diagnostic tool to evaluate various hematological and non-hematological disorders. The two most important techniques used for the diagnosis are bone marrow aspiration and bone marrow biopsy which play complementary role with each other when performed simultaneously. Aims and Objectives: Study was done to compare the results of BMA and BMB and by that to prove the complementary role of both techniques to each other. Material and Methods: We evaluated total 74 cases in central laboratory, department of pathology, at tertiary care centre. All aspirations were stained by giemsa and iron stain while all biopsy were stained by routine H&E stain. Reticulin stain and IHC markers were used as and when required. Result: Out of total 74 cases, 40 cases showed positive corelation between these two techniques (54%). In two cases aspiration was not possible. In 8 cases biopsy was not done. 4 cases showed crushing artefact in BMB while 3 cases of aspiration were either diluted or dry tap. In all these cases diagnosis became possible by the alternate technique. BMB replaced BMA and vice versa as and when required. Conclusion: BMA and BMB are complementary procedure which yields extra support in diagnosing various hematological and non hematological disorders when one or other technique fails due to some reason
Prevalence and Associated Factors of Postnatal Care Utilization Among Women Attending Immunization Clinic in Health Centers in Hawassa City , Southern Ethiopia,. 2019
Authors:   College of Medicine and Health Science, School of Nursing, University of Gondar, Gondar, Ethiopia, Tegegne Eleni Tesfaye , Tessema Mekibib Kassa ,   Leishmania Research and Treatment Center, University of Gondar, Gondar, Ethiopia, Tegegne Kaleab Tesfaye ,   Department of Public Health, Hawassa College of Health Science, Hawassa, Ethiopia
Published: July 2021

Introduction: Postnatal care is a care provided to women and their babies within 42 days after deliveryA large proportion of maternal and neonatal deaths occur during the first 48 hours after delivery, and these first two days following delivery are critical for monitoring complications arising from the delivery World Health Organization (WHO) recommends that after an uncomplicated vaginal birth in a health facility, healthy mothers newborns should receive care in the facility for at least 24 hours after birth. If birth is at home, the first postnatal contact should be as early as possible within 24 hours of birth. Objective: To assess prevalence and associated factors of postnatal care utilization among women attending immunization clinics in health centers, Hawassa city, southern Ethiopia, 2019. Methodology: Institution based cross sectional study design was done. Study was conducted in all health centers .The total sample sizes were 306 women attending immunization clinic at health centers A random sampling technique was employed to select the study subjects. Data collection was conducted from study subjects using pretest questioners. The questioner was developed in English. Ethical clearance was obtained from the research unit of Rift Valley University. Data was entered and analyzed using SPSS version 20 for windows. Frequency distribution table and statically graph were used to describe the variables of interest. The associated factors of postnatal care utilization were identified using bivariate and multivariate analysis. Result: Multi parous women who had PNC experience were three times more likely to utilize PNC service for the current delivery than those primi Para women[ AOR=2.8, 95% CI (1.36-5.8)]. On the other hand, those multi parous women who hadn’t PNC experience were almost 50% less likely to utilize PNC for the current delivery than those primi Para women[AOR=0.43, 95% CI (0.20-0.92)]. Finally, those women who were discharged from the institution after delivery at less than 6 hrs of stay were almost 80% less likely to utilize PNC than those women who stayed more than 24hrs [AOR= 0.22, 95% CI (0.06-0.83)]. Conclusion: The overall prevalence of PNC service utilization in this study was relatively good as compared to the HSDP IV report for Hawassa city in the 2006 EFY. PNC counseling and provision of appointment, counseling on danger sign, past experience of PNC utilization, and less than 6 hours stay at health institution before discharge were found to statistically significant for the current PNC service Utilization
Application of Machine Learning in Google Services- A Case Study
Authors: Pulluparambil Siji Jose , Bhat Subrahmanya
Published: July 2021

Purpose: Google Search is currently the most preferred search engine worldwide, making it one of the websites with the highest traffic. It assists people in discovering the content they are searching for, from the large repository of the World Wide Web. Google has grown to be the best in the search engine market that it is the single most important variable to be considered when optimizing a website for search. There are many ranking algorithms used by Google to make the searching process more precise. Google has the vision “to provide access to the world's information in one click”. Machine learning is the most popular methodology applied in predicting future outcomes or organizing information to assist people in making required decisions.ML algorithms are trained over instances or examples through which they analyze the historical data available and learn from past experiences. By repeatedly training over the samples, the patterns in the data can be identified in order to make predictions about the future. Google, as an organization, can be a pioneer in ML, and as a technology product, can be a use case for machine learning. Here, a case analysis has been prepared on few applications of machine learning in the products and services of Google. Within this paper, we highlight their technological history, services with machine learning applications, financial plans, and challenges. The paper also tries to examine the various products of Google which apply ML, such as Google Maps, Gmail, Google Photos, Google Assistant, and review the algorithms used in each service.
Approach: The detailed survey method on secondary data is used for analysing the data.
Findings: Based on the developed case study, it is clearly evident that Google is using machine learning algorithms with few artificial intelligence features to enhance the quality of the services they provide.
Originality: A new way of analysis was performed to identify the methods used in the organization’s services.
Paper Type: Descriptive Case Study Research
A Combined Experiment and Modeling Analysis of ASTM G85 WB Accelerated Corrosion Testing of Galvanically Coupled Sensitized AA5456-H116 and CDA 706 Cupronickel
Authors: Blohm L.M. , Liu C. , Kelly R.G.
Published: July 2021

AA5456-H116 undergoes accelerated localized corrosion when in a galvanic couple with cupronickel alloy C70600 (CDA 706) during ASTM G85 Appendix 2 Wet Bottom (G85 WB) testing. Surface and subsurface damage of AA5456-H116 and the region of protection of the C70600 were investigated and quantified after 31 d (124 cycles). These results were compared to finite element modeling results investigating relative humidity (RH) and water layer (WL) thickness. The best fit between experimental results and the modeling results was found when modeling assumed that a 3,000 μm water layer was formed during the spray portion at the start of each G85 cycle, with thinner water layers present during the decreasing RH portion of the cycle, which led to intergranular corrosion attack that was primarily focused in the proximity of the C70600/AA5456-H116 interface, but extending along the AA5456-H116 surface for some distance. The high-water layer thickness is likely the result of the corrosion product formation that traps additional electrolyte than would be present on a clean surface.
NATUREZA COMO FATO CULTURAL - O CONDEPHAAT E AS POLÍTICAS PÚBLICAS DE MEIO AMBIENTE
Authors: Detoni Sandro Francisco
Published: July 2021

Os elementos que compõem as estruturas físicas e biológicas da Terra são dotados de importância cultural em razão de suas dimensões simbólicas formais ou epistemológicas. Este artigo analisou os argumentos que embasam a inclusão da defesa e proteção da natureza no contexto das políticas culturais, o que pressupõe o reconhecimento de seus componentes como fatos culturais. Apresentam-se as premissas que definem e constituíram o conceito de patrimônio cultural, cujo sustentáculo fundamental está na própria amplitude simbólica dos bens culturais, engendrada nas relações sociais entre os membros de uma comunidade (ou sociedade) e dos grupos sociais com o suporte físico-natural. Tal característica corrobora a inclusão dos distintos componentes do quadro natural como um dos focos das políticas pública da área cultural, mais especificamente, o reconhecimento por meio do tombamento natural. Analisaram-se também os dados e o histórico sobre os tombamentos efetuados no Conselho de Defesa do Patrimônio Histórico, Arqueológico, Artístico e Turístico de São Paulo e as contribuições metodológicas da ciência geográfica, as quais possibilitaram a definição de critérios para a identificação dos atributos naturais dotados de significância cultural.
Avaliação da motivação de escolares à participação de jogos interclasse de escola pública municipal em Fortaleza – CE
Authors: Cavalcante Vitória Correia Queiroz , Braz Letícia Maria Alves , Santos Ana Luisa Batista , Oliveira Antônio Ricardo Catunda de
Published: July 2021

Objetivou-se identificar fatores de motivação sobre a importância dos jogos interclasse para os alunos após um projeto de intervenção na escola. Trata-se de um estudo descritivo, exploratório e de abordagem quantitativa. A amostra total foi composta por 108 alunos de ambos os sexos, entre uma faixa etária de 11 a 15 anos do Ensino Fundamental Anos Finais de uma escola pública. Foram utilizados como instrumentos de coleta de dados um questionário socioeconômico e o Participation Motivation Questionnaire (PMQ). Os resultados mostraram que a “Competência Técnica” é o principal fator motivacional dos alunos, seguido dos aspectos “Aptidão Física”, “Competição” e “Diversão”. No processo de interpretação dos dados obtidos destacou-se que alguns fatores podem estar relacionados a tal resultado, entre eles, o pouco tempo de intervenção do projeto e o próprio ambiente escolar.
30 Ağustos Dumlupınar Zaferinin Bir Propaganda Aracı Olarak “Yunan Mezalimi” İsimli Tiyatro Oyununa Yansımaları
Authors: ADAY Erdal , GÖKDÜL Ali
Published: July 2021

Kütahya Mecmuası’nda, Hamza Güner tarafından 1927 yılında parça parça yayınlanmış olan “Yunan Mezalimi-Türk Zaferi” isimli tiyatro oyununda, işgal döneminde Kütahya köylerinde Yunanlılar tarafından yapılan zulümler anlatılmıştır. Milli Mücadele Dönemi, 30 Ağustos zaferine giden yolda, Yunanlılar Kütahya ve çevresine büyük zararlar vermişlerdir. Yunan zulümleri, iaşe ve paralara el koyma, tehdit ve işkence gibi boyutları aşmış; ırza geçme ve cinayet ile sonuçlanma boyutuna ulaşmıştır. Yunan egemenliğinin hakim olduğu bu evrede, köylüler silahsızlandırılmış ve bir köyden diğerine gitme yasaklanmıştır. Casuslarla iç içe bir yaşam süren Kütahya köylüleri temkinli ve kararsız olup çaresizliği tüm benliklerinde hissetmişlerdir. Yunanlılar, Büyük Taarruz esnasında, uğradıkları yerleri, içerisinde insanlar olduğu halde, ev ve harmanlarıyla birlikte yakmaya başlamışlardır. Köylüler, bozulan düşmanın köylerini yakmasından ve öldürülmekten dolayı korku içinde Türk Ordusu tarafından kurtarılmayı beklemişlerdir. Bu süreçte yaşanan acıklı ve dramatik olaylar, vicdanları titretecek boyutta elimizdeki tiyatro oyununda ifade edilmiştir. Büyük Taarruz öncesi Dumlupınar ve birçok köyün genel vaziyeti hakkında bir panorama sunan bu edebi eser, ayrıca olaylar kritik edildiğinde, Kütahya’nın Milli Mücadele tarihine ilişkin bir yol gösterici olma niteliği taşımaktadır.
Yaratıcı Yönetim ve Yaratıcı Örgüt -Seramik Tasarım ve Üretimine Dayandırılmış Keşfedici Bir Araştırma-
Authors: KARA Hakan
Published: July 2021

Bu araştırmanın amacı, seramik tasarım ve üretimine dayandırılmış keşfedici bir araştırma ile yaratıcı yönetim ve yaratıcı örgüt olmaya etki eden faktörleri belirlemektir. Nitel bir araştırma yöntemi olan Gömülü Kuram’dan yararlanılmıştır. Araştırmada yarı yapılanmış sorular yönlendirici olmuştur. Bu kapsamda yaratıcı yönetim ve yaratıcı örgüt odaklı olarak, işletmelerin bölge ve şehir konumlanmasında dikkate aldıkları faktörler, işgörenleri nasıl buldukları, müşteri istek ve beklentilerini nasıl belirledikleri, tasarım karar süreçlerini hangi aşamalardan geçirdikleri, pazar riskleri karşısındaki stratejilerinin neler olduğu, örgütlerin fiziksel yapılarının özellikleri ve bilgi ihtiyaçlarını nasıl karşıladıkları araştırılmıştır. Yaratıcı yönetim ve yaratıcı örgüt olmada konumlandırma kararı, yaratıcı işgören istihdam kararı, yaratıcı odaklı inovasyon, yaratıcı tasarım karar süreci, yaratıcı tasarıma ilgisizlik riski karşısında stratejiler, yaratıcı fiziksel donanımlar ve yaratıcı bilgi ihtiyacı gibi faktörlerin etkili olduğu ortaya konulmuştur.