bluuebunny/crossref_metadata_2025 huggingface dataset:
The assessment of economic affordability of antiviral herbal medicines presented at the domestic pharmaceutical market
Authors: Khodakivska V. , Senkiv N.
Published: April 2022

One of the most urgent problems of our time is the high morbidity and mortality of people from viral infections, which can affect almost all organs and systems of the host body. Significant damage to the health of the population and the economy of countries is caused by the incidence of viral diseases. An important issue in the process of pharmacotherapy of patients with viral infections is to provide them with a sufficient number of effective, safe and affordable drugs, especially during the coronavirus pandemic, which humanity actively fought during 2019-2020 and is still fighting today.
Aim. To conduct the marketing analysis of the range of antiviral herbal medicines presented at the pharmaceutical market of Ukraine during 2019-2020 and their marketing characteristics.
Materials and methods. The study used a list of antiviral herbal medicines according to the State Register of Medicines of Ukraine, the Compendium, and scientific articles of professional publications. The main research methods were systematic, comparative, marketing analysis of the drug market structure, monitoring and graphical method.
Results and discussion. According to the PBX international classification system, antiviral medicines based on the plant raw material belong to the group of drugs applied as antimicrobial agents for systemic use. According to the PBX classification, medicines that mainly belong to the J05AX ** group – “Antiviral drugs for systemic use. Antiviral drugs.Others.” were of interest. It was found that as of 01.01.2019, the Ukrainian market of the group studied was formed by domestic manufacturers, there were 4 names of medicines and 4 manufacturing companies. Drugs were presented at the pharmaceutical market in the form of drops, syrups, suppositories and tablets. It was determined that the most available drugs within 2019-2020 were Altabor, Erebra and Flavovir although during the study period there was a steady increase in prices for drugs of this group at the pharmaceutical market. Therefore, it should be noted that from year to year their affordability for consumers decreases.
Conclusions. The marketing research has been performed, and the assortment structure of antiviral herbal medicines presented at the pharmaceutical market of Ukraine has been analyzed. The indicators characterizing the market situation, such as offers, product range, price dynamics and the coefficients of availability, adequacy of solvency, etc., have been studied.
Analysis of the use of PR-technologies by domestic pharmaceutical enterprises in the implementation of socially oriented marketing in the conditions of the global COVID-19 pandemic
Authors: Pestun I. V. , Babicheva G. S. , Zhadko S. V.
Published: April 2022

Today, leading foreign and domestic pharmaceutical companies are aware of the importance of using socially oriented tools of marketing communication to achieve economic stability, strengthen competitive positions and form a positive image at the pharmaceutical market.
Aim. To study PR-technologies used by domestic pharmaceutical companies as part of the implementation of the concept of socially oriented marketing in the global COVID-19 pandemic.
Materials and methods. The methods of logical and meaningful problem formation, desk marketing research, the content analysis of publications in scientific and practice-oriented medical and pharmaceutical literature were used in the work.
Results and discussion. The issues of social responsibility of pharmaceutical industry enterprises as a key factor in the successful development of companies under the conditions of coronavirus infection have been highlighted. The specificityhas been considered, and the features of modern PR-tools of pharmaceutical companies have been determined. The Internet resources play an important role among them. The content analysis of the web-sites of the TOP-5 major manufacturers of drugs at the pharmaceutical market of Ukraine has been conducted; the social responsibility areas and the main PR-technologies have been analyzed.
Conclusions. It has been found that the leading domestic pharmaceutical companies take an active public position and constantly implement various social programs aimed at supporting the society welfare, especially in the conditions of the COVID-19 pandemic. The information content of the sites of the enterprises under study fully reflects the activities of companies in the field of public relations on the principles of openness, relevance, reliability and social responsibility. Considerable attention is paid to the quality, safety and availability of pharmaceutical products and the provision ofappropriate assistance to healthcare institutions in the fight against COVID-19.
The choice of excipients and optimization of the composition of orally disintegrating tablets based on paracetamol and N-acetyl-D-glucosamine
Authors: Zupanets I. V. , Ruban O. A.
Published: April 2022

Aim. The choice of the qualitative and quantitative composition of excipients to provide the required mechanical strength and disintegration time when developing a pharmaceutical composition in the form of orally disintegrating tablets (ODT) based on paracetamol and N-acetyl-D-glucosamine.
Materials and methods. The study object was pharmaceutically accepted excipients used in the pharmaceutical development of solid dosage forms. To conduct the statistical analysis of experimental data, a Minitab® 19.1.1 software was used.
Results and discussion. The excipients (povidone of different brands, copovidone, crospovidone of different brands, croscarmellose) used when developing ODT were considered, and it was determined that copovidone and crospovidone type A showed the most optimal quality indicators of the composition. It was found that the particle sizeof crospovidone and the route of its introduction affected the rate of disintegration in the aqueous medium. Using the method of mathematical prediction the optimal content of excipients in the composition and the experimental confirmation ofthe quality indicators of the mixture selected to create ODT were determined.
Conclusions. Excipients used in the development of ODT have been considered, and the excipients exhibiting the best quality indicators of the compositions have been found. Both the influence of the particle size of crospovidone, and the route of its administration have been determined. The optimal content of excipients in the composition and their experimental confirmation have been determined due to mathematical prediction.
Development of a methodological approach to determine regression equations in the study of the technology for manufacturing tablets based on quercetin
Authors: Kutova O. V. , Kovalevska I. V. , Demchenko N. V.
Published: April 2022

When developing the technology of tablets and tablet masses one of the tasks is to determine the amounts of excipients required to obtain pharmaco-technological quality indicators that meet the requirements of the State Pharmacopoeiaof Ukraine (SPhU).
Aim. To develop an algorithm for determining the type of three-factor mathematical models with dependent variables.
Materials and methods. The study object was experimental observations of the quantitative effect of excipients in the tablet composition based on a solid dispersion of quercetin on the pharmacopeial characteristics of this dosage form, in particular on its flowability. The experimental data were processed by the planned experiment using Mathcad 15 and MS Excel software according to the algorithm proposed.
Results and discussion. It has been found that the identification of mathematical models in pharmaceutical studies with three dependent factors, which total value is determined by the quantitative composition of the dosage formand fixed at a certain level, is difficult to perform due to the difficulty of interpreting the multiple regression parameters as characteristics of factors in isolation through their correlability. It has been proven that the replacement of variablesleads to the determination of a mathematical model that does not reveal the mechanism of the factors’ action and is a static description of their overall impact on the indicator studied.
Conclusions. As a result of the research conducted, regression equations were found to determine the effect of the amount of these excipients on the tablet flowability. It has been found that the most influential role in determining the target in the factor space studied is played by the interaction of factors. The algorithm for determining the mathematical description of the dependence with three variables has been proposed. Based on the fact that the research is conditioned by strict conditions in the quantitative composition, the chosen mathematical model of the dependence of the quadratic equation with two factors, for which there are limitations, has no correlation. The model determined is characterized by the possibility of providing the graphical interpretation and simplification of analysis and can be used for forecasting and optimization.
The theoretical substantiation of the composition of a wound-healing ointment with active components of plant origin
Authors: Trembach O. I. , Khokhlenkova N. V.
Published: April 2022

Aim. To theoretically substantiate the composition of a wound healing ointment with active substances of plant origin for the therapy in the second and third phases of the wound process.
Materials and methods. The study object was the generalization and analysis of scientific literature data on the use of medicinal plants in the treatment of the wound process.
Results and discussion. Based on the analysis of scientific literature data on the chemical composition and pharmacological properties of medicinal plants used in the treatment of the wound process, the expediency of using the lipophilic extract of marigold flowers, amaranth oil, fennel essential oil as active ingredients in the wound healing ointment has been substantiated. Marigold flowers due to the presence of a large number of carotenoids and flavonoidswill provide a high level of the antimicrobial, reparative action of the ointment. Due to the content of complex biologically active compounds, such as tocopherols, polyunsaturated fatty acids, vitamins, phytosterols and squalene, the amaranth oil has a pronounced antioxidant activity. The components that are part of the essential oil of fennel contributeto the connective tissue growth and the skin restoration, as well as provide a high level of the antifungal action.
Conclusions. The analysis of scientific literature data has shown the possibility of using herbal medicines in the treatment of the wound process. The greatest advantage of herbal medicines is the high degree of assimilation of molecules of biologically active substances, which are part of natural compounds as the most physiological form, by skin cells. The expediency of using the lipophilic extract of marigold, amaranth oil and fennel essential oil when developing a wound-healing ointment has been proven. The composition selected will provide the predicted antibacterial, antifungal, antioxidant and reparative effect of the ointment, reduce the likelihood of resistance in pathogenic microorganisms, and accelerate granulation and epithelialization of tissues.
The study of factors affecting the socio-psychological climate in the labor collective of a pharmacy institution
Authors: Andrienko N.V.
Published: April 2022

Aim. To study the theoretical foundations of the socio-psychological climate of a pharmacy institution and determine the factors affecting it.
Materials and methods. The methods of generalization, analysis and synthesis, content analysis were used in the study. An expert survey was used to determine the factors affecting the socio-psychological climate in the pharmacy. All members of the staff working in the pharmacy took part in the survey. The total number of respondents who participated in the expert study was 563 pharmacists. The study covered all regions of Ukraine. The results of the survey are significant and consistent.
Results and discussion. The approaches to defining the essence of the “socio-psychological climate” concept have been studied. The generalized definition of “socio-psychological climate of a pharmacy institution” can be defined as the mood and relationships developed in the labor collective and manifested as a set of psychological conditionsthat promote or hinder joint activities and the personal development of each employee. Factors affecting the sociopsychological climate in the labor collective of the pharmacy have been studied.
Conclusions. The socio-psychological climate is the result of joint activities of members of the labor collective and their interpersonal interaction; it is manifested itself in the mood and opinions of the team, well-being and assessments of the pharmacist’s living conditions in the team and expressed in relationships related to work and the solution of common tasks.
Determination of ionization constants for sequinidazole in aqueous solutions and mixtures of water with isopropanol, acetonitrile and ethanol
Authors: Shovkova Z. V. , Tkachenko O. V. , Seniuk I. V.
Published: April 2022

Seknidazole is a drug from the 5-nitroimidazole group with a number of side-effects. This drug is virtually unexplored from the point of view of chemico-toxicological analysis (CTA). Therefore, the development of a set of methods for the detection and quantification of secnidazole in biological fluids for use in CTA is an urgent task.
Aim. To study the acid-base equilibrium of secnidazole in aqueous solutions and mixtures of water with amphiphilic solvents and determine the corresponding ionization constants.
Materials and methods. Spectrophotometric measurements were performed using a SPEKOL®1500 single-beam spectrophotometer. An EV-74 ionomer was used to control the pH of the solutions. Seknidazole solutions in the concentrationof 1000 μg/ml were used in the experiment.
Results and discussion.  Absorption spectra of secnidazole in water and mixtures of water and amphiphilic solvents in the pH range studied showed four isobestic points characterizing two protolytic equilibria (equilibrium 1 – 240 and 295 nm, equilibrium 2 – 261 and 297 nm). The position of the isobestic points of equilibrium 2 fluctuated in the range ± 3 nm; it was due to the presence of tautomeric transformations for the molecular form of secnidazole.
Conclusions. The acid-base equilibria of secnidazole in aqueous solutions and mixtures of water with amphiphilic solvents have been studied. It has been shown that in a strongly alkaline medium there is an anionic form of secnidazole R–, with further decrease in the pH value the molecular form HR appears, in a strongly acidic medium the final product – a protonated form H2R+ – is formed. The ionization constant 1 has been determined for aqueous solutions of secnidazole, mixtures of water with isopropanol, acetonitrile and ethanol. It is impossible to determine the equilibrium constant 2 by the method specified.
Substantiation of the target quality profile and risk assessment in the development of a combined drug for injection
Authors: Semenova K. M. , Almakaieva L.
Published: April 2022

Aim. To substantiate the target quality profile for planning the development of a combined drug for injection based on sodium hyaluronate (SH) and dihydroquercetin (DHQ) with an expanded spectrum of the specific activity, as well as to determine the risk factors affecting the quality of the combined drug for injections at the stage of pharmaceuticaldevelopment (PD).
Materials and methods. The study objects were the active pharmaceutical ingredients (АРІ) of SH, DHQ and a drug in the form of a solution for injection based on them, as well as potential risk factors affecting the quality of the product. The target product quality profile (QTPP) was developed based on the review and analysis of scientific literature, materials of the State Register of Medicines of Ukraine, pharmacopoeias of the leading countries of the world, articles of scientific publications. The Ishikawa diagram was used to analyze potential risk factors for a drug for injection at the stage of PD.
Results and discussion. The application of scientific approaches to the analysis of scientific materials from various information sources on combination therapy with drugs with multidirectional medicinal substances and the availability of information on parenteral medicines (PM) allowed us to plan a QTPP for the development of a combined drug for injection for intradermal administration. In order to identify the most dangerous factors affecting the quality of the drug, the causal analysis of these factors at the PD stage of the combined drug for injection was carried out, and an Ishikawa diagram was constructed.
Conclusions. The QTPP has been developed. The expected set of quality indicators that would ideally be achieved to ensure the required quality of the drug has been determined taking into account its safety and efficacy. Based on the risk assessment methodology, the Ishikawa diagram for a combined drug for injection has been constructed; potential risks associated with the quality of active ingredients (AI) and excipients, quality of primary packaging, production conditions, quality control of the drug, the technological process affecting the quality of the combined drug for injection and the causes leading to deviations from these indicators have been identified. This diagram is used as a baseline for the overall assessment of quality risks at the stage of drug development.
Coronary disease with fatal disclosure in 9-year-old child: a case report
Authors: Carmo Lucas , Lima Maria , Miranda Rogério
Published: April 2022

This article is about a 9-year-old male child with chest pain and clinical signs of hypercholesterolemia. During medical investigation we confirmed primary hypercholesterolemia and diagnosed bicuspid aortic valve and severe coronary disease, this being the cause of chest pain. Unfortunately, the patient evolved to death during the procedure, despite a successful coronary stent implantation and cardiac resuscitation. Atherosclerotic disease is rare among children, being commonly associated to familial forms of hypercholesterolemia. Bicuspid aortic valve, on the other hand, is a common congenital heart disease, but the association between both is rarely described. Chest pain is a common cause of complaint, and although in the vast majority of cases it is not associated with cardiac etiology, in the setup of hypercholesterolemia, especially familial forms, it should prompt the pediatrician attention to threatening etiology.
Sezgisel Bulanık TOPSİS Yöntemiyle Portföy Seçimi: Borsa İstanbul’da Bir Uygulama
Authors: KARCIOĞLU Reşat , YALÇIN Selçuk
Published: April 2022

Bu çalışmada, Borsa İstanbul’da (BİST) yer alan firmalar içerisinden en iyi performans gösteren firmalar belirlenerek bu firmalara ait hisse senetlerinden oluşturulan farklı portföylerin performansları analiz edilmiştir. Portföylerde yer alacak hisse senetlerinin seçiminde, Sezgisel Bulanık TOPSIS yöntemi kullanılmıştır. Çalışmada 5 yıl boyunca (2015, 2016, 2017, 2018, 2019) 15 farklı portföy oluşturulmuş ve bu portföylerin performansları birbirleriyle ve BİST 100 endeksiyle karşılaştırılmıştır. Sezgisel Bulanık TOPSIS yöntemiyle seçilen hisse senetleriyle oluşturulan portföylerin hem yükselen hem de düşen piyasalarda, BİST 100 endeksinden çok daha iyi bir performans gösterdiği tespit edilmiştir. Çalışmanın sonucunda Sezgisel Bulanık TOPSIS yönteminin portföye dahil edilecek hisse sentlerini belirlemek için kullanışlı bir yöntem olduğu ve yatırımcıların portföy oluştururken bu yöntemi kullanmalarının yararlı olacağı sonucuna ulaşılmıştır.
İhtiyaç Kredisi Talepleri Anında Finansal Okuryazarlık Düzeylerinin Belirlenmesi: Sivas İlinde Bir Araştırma
Authors: DEMİR Mehmet , ELDEN ÜRGÜP Seval
Published: April 2022

Bu çalışmanın amacı, geleneksel veya katılım bankalarına ihtiyaç kredisi için başvuran kişilerin, kredi talepleri anında finansal okuryazarlık düzeylerinin belirlenmesidir. Bu amaca ulaşmak için, Sivas ilinde faaliyet gösteren geleneksel ve katılım bankalarına ait 38 şubeye, bireysel ihtiyaç kredisi için başvuran 150 kişi üzerinde 29 Mart-8 Temmuz 2021 tarihleri arasında anket uygulanmıştır. SPSS paket programı kullanılarak verilere ait frekans, aritmetik ortalama, standart sapma, Anova ve çoklu karşılaştırma analizleri yapılmıştır. Araştırma sonucunda, bireylerin kredi talebi anında genel olarak finansal okuryazarlık düzeylerinin yüksek olmadığı; ancak bankaların kredi tahsis uygulamalarına ait bilgi düzeylerinin yüksek olduğu; %82’sinin daha önce de ihtiyaç kredisi kullandığı; bu bireylerin %74’ünün geleneksel bankaları, %8’inin ise katılım bankalarını tercih ettiği tespit edilmiştir. Ayrıca, kadınların finansal okuryazarlık düzeylerinin erkeklerin finansal okuryazarlık düzeylerine göre daha yüksek olduğu ve lisansüstü eğitim alan bireylerin finansal okuryazarlık düzeylerinin ilköğretim ve lise düzeyindeki bireylere göre anlamlı derecede daha yüksek olduğu sonucuna ulaşılmıştır.
Lisanslı Depoculuk Sektöründe Faaliyet Gösteren Şirketlerin İşlem Performanslarının Çok Kriterli Karar Verme Yöntemleriyle Ölçülmesi
Authors: ERGUN Huseyin , GÜLAL Metin , KILIÇARSLAN Abdullah
Published: April 2022

Bu çalışmanın amacı, lisanslı depo şirketlerinin Ocak 2018-Kasım 2021 dönem aralığındaki işlem performanslarının, Çok Kriterli Karar Verme (ÇKKV) yöntemlerinden TOPSIS ve ARAS yöntemleri ile değerlendirilmesidir. TOPSIS ve ARAS yöntemleri kullanılarak elde edilen sonuçlar, Copeland yöntemi ile birleştirilmiş ve sonuçlar, Takasbank sıralama verileri ile mukayese edilmiştir. Türkçe literatürde, lisanslı depo şirketlerinin işlem performanslarına yönelik bütüncül bir çalışmaya rastlanmamıştır. Dünya örneklerinde, lisanslı depoculuk sektörüne yapılan yatırımlar çok büyük boyutlara ulaşmış ve ürün piyasalarında artan işlem derinliği ile yatırımcılar daha fazla kazanç elde etmeye başlamışlardır. Lisanslı depoculuk sistemini başarıyla uygulayan ülkeler, tarımsal emtia üretimi ve ticaretinde sürdürülebilir rekabetçi yapılarıyla, kayıt dışı ticareti kayıt altına almakta ve vergi gelirlerinde artış sağlamaktadırlar. Bu kapsamda, Türkiye’de sektör şirketlerinin dahakarlı ve yatırımlarının geri dönüşlerinin daha hızlı olabilmesi açısından işlem performanslarının tespit edilerek ortaya konulması son derece önemlidir. Bu bağlamda, çalışmanın lisanslı depoların işlem performanslarına yönelik olarak literatüre katkı sunması beklenmektedir. Çalışma sonucunda, Copeland sonuçları ile Takasbank sıralama verileri açısından, en iyi işlem performansını sağlayan şirketlerin, KAİNAT, TOPRAK ve MYSİLO olduğu tespit edilmiştir.
İmalat Ve Hizmet Sektörlerinde Karlılık Oranlarını Etkileyen Faktörlerin Analizi
Authors: DEMİRHAN Dilek
Published: April 2022

Bu çalışmada TCMB reel sektör istatistikleri kapsamında yayımlanan bilanço ve gelir tabloları kullanılarak imalat ve hizmet sektörlerinde karlılık oranlarını etkileyen faktörler araştırılmıştır. 141 adet alt sektörün imalat ve hizmet kategorilerine ayrılarak veri setine dâhil edildiği ve her alt sektörün panel veri setinde bir birim olarak ele alındığı çalışmada dinamik panel veri analizi gerçekleştirilmiş ve aktif karlılığı, brüt kar marjı, faaliyet kar marjı ve net kar marjı oranlarının bağımlı değişken olduğu dört model test edilmiştir. İki sektörde de bütün karlılık oranlarını aynı yönde etkileyen değişkenler asit-test oranı (pozitif) ve gayrisafi milli hasıla (GSMH-negatif)’dır. İmalat sektöründe üretici fiyat endeksi (ÜFE) ve faiz kazanma oranının tüm karlılık göstergelerini pozitif etkilediği, borçlanma oranının karlılığı etkilemediği, aktif devir hızının aktif karlılığını pozitif, brüt kar marjını ise negatif etkilediği saptanmıştır. Hizmet sektöründe ise borçlanma oranının tüm karlılık oranlarını negatif, ÜFE’nin aktif karlılığı ve net kar marjını negatif, diğer karlılık oranlarını pozitif, aktif devir hızının brüt kar marjını negatif etkilediği bulunmuştur.
Story of a Boy, a Mother, and a Mountain
Authors: Aditia Patra
Published: April 2022

Komik, meski sempat diperdebatkan terkait posisinya dalam peta seni rupa, namun pada akhirnya kian diterima terutama sejak tahun 1960-an. Sejak itu, karakteristik komik terus diidentifikasi dan kemudian ditemukan bahwa representasi yang dihadirkan dalam komik cenderung lebih partikular, spesifik, dan kontekstual, sehingga cukup sering digunakan untuk menampilkan konteks-konteks budaya tertentu. Komik berjudul Story of A Boy, A Mother, and A Mountain, yang dipamerkan di Indonesian Art Award (IAA) 2018, memang berusaha untuk tidak mengaitkan dengan konteks kebudayaan tertentu - setidaknya tidak secara gamblang -. Namun bagi pembaca yang memahami konteksnya, dan punya pengetahuan tentang mitos Gunung Tangkuban Parahu atau Legenda Sangkuriang, kemungkinan besar akan mengaitkan ke arah sana berdasarkan latar, alur, dan representasi simboliknya. Gunung Tangkuban Parahu sendiri merupakan gunung yang berada di Jawa Barat dan keberadaannya lekat dengan tradisi serta kebudayaan Sunda. Di balik keberadaan gunung yang menjadi salah satu objek wisata penting di Jawa Barat tersebut, terdapat mitos yang dikenal luas, yang sering disebut dengan Legenda Sangkuriang. Mitos Legenda Sangkuriang tersebut ditampilkan oleh komikus dalam bentuk komik tanpa teks narasi, tanpa visualisasi wajah, dan lebih menggunakan panel yang sifatnya cair dan dinamis. Alasan di balik pertimbangan estetika tersebut adalah penekanan aspek bawah sadar sebagai ekspresi dari konsep oedipus complex dalam psikoanalisis Sigmund Freud, titik berat karya yang bukan pada narasi, melainkan pada sensasi dan gairahnya, sebagaimana konsep Dionysian dalam pemikiran Friedrich Nietzsche, serta aspek historis-kultural dari komikus yang ingin menampilkan komik dan cerita yang sesuai dengan latar belakang personal, dengan juga mengharapkan suatu otentisitas yang muncul dari kebudayaan Jawa Barat dan tradisi Sunda.
Authors: Subkhi Muhammad Nanda Restu , Fardilla Ucik Ana
Published: April 2022

Film Tilik (Ladies on Top) menunjukkan bahwa genre film yang disukai oleh publik Indonesia bukan hanya tentang hal-hal erotis atau memilki durasi waktu yang lama. Film ini menjadi fenomenal sejak di unggah pada Agustus 2020 di platform You Tube, yang dapat dilihat secara gratis. Tidak hanya menjadi trending topic di internet namun juga menjadi perbincangan di kehidupan nyata. Peneliti menggunakan model Kineikonic Andrew Burn yang membagi aspek film menjadi Embodied Modes, Visual Modes, Auditory Modes. Tujuan penelitian ini adalah mengetahui aspek-aspek yang membangun sebuah film yaitu ekspresi wajah , kostum, make up, desain set, pencahayaan, dan pengambilan gambar. Hasil penelitian ini menjabarkan kesinambungan antara aspek-aspek baik naratif maupun sinematik dalam film. Film ini mampu menghadirkan budaya lokal dengan penggunaan bahasa.
Studi Komparasi Partisipasi Dalam Proses Perancangan Material Terbarukan
Authors: Puspita Eka Arifianty , Kahdar Kahfiati
Published: April 2022

Pendekatan partisipasi telah lama dikenal dalam proyek desain berkelanjutan. Beberapa inovasi material terbaru pun berupaya menunjukkan partisipasi masyarakat dalam proses desain mereka untuk mencapai hasil yang berkelanjutan. Namun, terminologi partisipasi dapat dipahami dan diterapkan secara berbeda bagi para aktor yang terlibat dalam proses. Menanggapi pemahaman yang beragam tentang partisipasi, tulisan ini mencoba mengkaji implementasi partisipasi dalam proses perancangan dua inovasi material terbarukan yang terkenal, yaitu Totomoxtle dan Pinatex. Metodologi yang digunakan dalam penelitian ini adalah deskriptif komparatif yang dianalisis melalui studi pustaka dan perbandingan dengan merujuk pada teori tangga partisipasi yang digagas oleh Arnstein, bentuk partisipasi oleh White, dan partisipasi dalam desain oleh Lee. Berdasarkan hasil analisis, terdapat perbedaan tingkat inklusi dalam partisipasi yang dimiliki oleh para aktor dan juga bentuk partisipasi yang beragam. Selain itu, melalui studi komparasi, terlihat para aktor yang berada pada tingkat partisipasi yang sama ternyata tidak secara langsung menampilkan bentuk dan fungsi partisipasi yang serupa. Keanekaragaman bentuk dan tingkat partisipasi dalam proses perancangan inovasi berkelanjutan tersebut membentuk jenis relasi dan ruang interaksi yang berbeda diantara desainer dan aktor lain yang terlibat.
Eksplorasi Ekstrak Pewarna Alami Sebagai Bahan Pewarna Organik Untuk Tekstil Cetak
Authors: Abdurahman Syahida Nisa , Kahdar Kahfiati
Published: April 2022

Upaya pelestarian lingkungan gerakan sustainable living yang mengarahkan masyarakat untuk kembali menggunakan bahan-bahan yang ramah lingkungan khususnya dalam penciptaan produk tekstil. Terkait isu tersebut salah satu langkah yang dapat dilakukan yaitu mengurangi limbah tekstil yang terbuat dari bahan sintetis dengan menciptakan tinta organik yang dapat menjadi alternatif tinta dalam proses cetak tekstil. Penelitian ini menggunakan pendekatan kuantitatif dengan metode eksperimentatif yang dianalisa secara kualitatif. Melalui tahap eksperimen larutan ekstrak beberapa zat pewarna alam yang ditambahkan zat pengental alginat, guar gum dan tepung tapioka. Larutan tinta organik diterapkan pada tekstil berbahan 100% katun menggunakan teknik sablon dan diakhiri dengan proses fiksasi post-mordanting. Tujuan dari eksperimen ini untuk mengetahui hasil paling optimal dari larutan pasta pewarna (tinta organik) terhadap daya serap, warna pada kain, uji kelunturan, hasil visual dan tekstur. Dari hasil eksperimen tersebut membuktikan proses pencetakan warna menggunakan bahan-bahan alam yang ramah lingkungan dengan teknik sablon pada tekstil dapat dilakukan. Setiap larutan ekstrak, zat pengental dan pengaruh zat mordan pada proses fiksasi memiliki daya serap yang berbeda sehingga menghasilkan warna dan hasil visual pada permukaan tekstil yang bervariasi.
Ikonisitas dalam Arsip Foto Karya Seni Rupa Dua Dimensional
Authors: Mukmin Patriot
Published: April 2022

Digitalization has brought new complexity to the issue of archival photographs of artworks. This paper explores the relationship between two-dimensional artwork and its representation in the form of digital archive photos. The author mobilizes the concept of the relation between representamens and objects in Charles Sanders Peirce's theory of signs. Based on the analyses carried out in this paper, the presence of the Icon and Index feels very strong in the case of archival photographs of works of art. This finding stresses the need of two types of archival photos of works, namely primary photos and secondary photos. Classification is carried out based on the level of similarity in the representation seen in the archive photo.
Diffusion Test of Fertility Decline in Arab Countries of the Middle East and North Africa (MENA) Region
Authors:   National Institute of Statistics and Applied Economics, GEAS3D Laboratory, Morocco, Drioui Chaimae , El Bidaoui Bouchra ,   National Institute of Statistics and Applied Economics, GEAS3D Laboratory, Morocco, Bakass Fatima ,   National Institute of Statistics and Applied Economics, GEAS3D Laboratory, Morocco
Published: April 2022

After a long period of resistance and indications reflecting a natural regime, with variable starting points and rhythms, fertility has finally transited in all Arab countries of the MENA region. This paper aims to analyze this fertility decline to identify precursors and laggards in the shift to conscious birth control and test whether this widespread and rapid decline results from a process of spatiotemporal diffusion. The data used are the United Nations estimates back to 1950. Two approaches are used for dating fertility decline: Schmertmann et al. (2010) is based on the total fertility rate, and Coale and Treadway’s (1986) method is based on Coale’s Ig marital fertility index. The Knox statistic was used for the diffusion theory test. According to the two methods, the clustering of countries does not show significant differences other than a few exceptions. However, the diffusion theory test yields different results for the two approaches used. For the first method, the test is significant at the 6% level, which indicates that birth control has occurred through a contagion process among countries. However, this diffusion process was not established using the second approach, which may result from social and intentional diffusion instead. The proximate and contextual characteristics analysis in the pioneer countries around the start-up shows that the settings were favorable. The new fertility behaviors emerged first from the elites and the cities.
Monetary policy instruments and the achievement of three macroeconomic goals in the USA and Japan
Authors: Afanasyeva Oxana Nikolaevna
Published: April 2022

Currently, the issues of the implementation of monetary policy, the use of its tools to achieve economic growth and other macroeconomic goals are particularly relevant. It is of great importance to identify the results of using various transmission channels in achieving the main macroeconomic targets. The use of monetary policy instruments can have both a stabilizing character and the opposite of what is expected, which must be taken into account when implementing monetary policy.The purpose of the study is to select monetary policy instruments to influence the achievement of such macroeconomic goals as: GDP growth, inflation, unemployment in the United States and Japan. The study develops the principle of "goals-tools" in relation to monetary policy. The possibility of achieving three macroeconomic goals simultaneously is being considered. В  The methodology of the study is represented by the theory of economic policy of Ya. Tinbergen. To assess the possibility of achieving three macroeconomic goals simultaneously (GDP growth, inflation, unemployment rate) in the USA and Japan due to changes in the use of monetary policy instruments, the toolkit of a system of independent equations has been implemented. The overall result of the study is to determine the impact of monetary policy instruments in order to achieve a combination of three macroeconomic goals in the United States and Japan. The analysis of the countries presented showed that each of them has a specific impact of instruments, even with a similar impact, its strength differs in different countries, which must be taken into account when using the same type of monetary policy instruments to achieve macroeconomic goals.
Apresentação v. 8, n. 16, jul./dez. 2021
Authors: Freitas Reis Marcos Vinicius de , Bartel Carlos Eduardo
Published: April 2022

Religião e política são dois fenômenos que, ao longo da história dialogam entre si, ambos andaram de mãos dadas, desde a antiguidade até a Revolução Francesa que, pelo menos em termos formais, os separou ao propor a noção de Estado laico. No Brasil as mediações entre religião e política, objeto de análise do presente Dossiê, foram juridicamente separadas com a proclamação da República em 1889. Tal separação ocorreu do ponto de vista jurídico e administrativo, sendo ambas as noções afastadas, mas de fato continuaram próximas através de inúmeras questões, que do religioso apolítico ao militante engajado perpassam visões de mundo, posicionamentos ideológicos, dos meios de comunicação, a questão do voto, das eleições e do comportamento eleitoral, entre muitos outros temas, compatíveis e incompatíveis, que propõem essa mediação entre religião e política...
Terras Prometidas
Authors: Bartel Carlos Eduardo
Published: April 2022

O artigo, utilizando fontes diversas, analisa às relações entre movimento sionista e judaísmo, seus distanciamentos e aproximações, articulando noções como religião, política e cultura ídiche com a ideia de construção de um Estado judeu. Nesse sentido, identifica diferentes propostas de territórios sugeridos para a formação deste Estado, isto é, espaços geográficos vinculados à diferentes interesses ideológicos e geopolíticos. Ao reconstruir essa história, transcorrida na primeira metade do século XX, igualmente, aborda sua repercussão entre os judeus radicados no Brasil e o papel da educação judaica em um contexto de transformações, conflitos e mediações entre diferentes concepções de judaísmo. A persistência do Estado de Israel enquanto problema histórico a ser estudado e, por vezes, o desconhecimento e/ou naturalização destas perspectivas e suas implicações no processo de criação deste Estado nacional justificam a presente abordagem.
Uma abordagem do marabaixo em perspectiva decolonial
Authors: Santos Nelson Mateus Machado dos , Reis Marcos Vinicius de Freitas , Silva David Junior de Souza
Published: April 2022

O Marabaixo é uma manifestação cultural afrodiaspórica praticada pelas comunidades negras do estado do Amapá. Tal expressão cultural é composta pela dança, música, percussão e orações. As rodas de marabaixo normalmente ocorrem nas festas de santos das comunidades negras amapaenses, dando destaque à cultura negra e ao catolicismo popular local. O presente artigo tem por objetivo analisar as dificuldades encontradas pelos marabaixeiros para efetivar na esfera pública direitos culturais específicos e acesso a políticas públicas. A metodologia adotada foi realização de entrevistas semiestruturadas com as principais lideranças do Marabaixo. Optamos pelas questões teóricas e metodológicas da teoria decolonial e afrodiaspórica para pensar a relação do Marabaixo com a esfera pública e Estado no contexto local amapaense.
Cadernos de história da educação
Authors: Kalinowski Gislaine Marli da Rosa , Alberto Thaienn Paes Leme , Leite Arthur Damasceno Ribeiro de Oliveira , Souza Sauloéber Tarsio de
Published: April 2022

O presente artigo tem o objetivo de fazer uma reflexão em torno da historiografia educacional brasileira, a partir de levantamento bibliométrico da Revista Cadernos de História da Educação da Universidade Federal de Uberlândia (CHE-UFU) entre os anos de 2002 a 2019. Ao investigar um dos principais periódicos especializados do país, apresentando uma análise quantitativa/qualitativa das informações evidenciadas, contribui-se para fomentar as discussões em torno desse campo científico. Entre outros elementos teóricos destaca-se o conceito de campo de P. Bourdieu, que permeia tanto a construção do objeto, como também da análise. A revista ora analisada surgiu em 2002 no interior do país por iniciativa de um grupo de pesquisa e se estabeleceu como importante canal de propagação de conhecimentos da área, principalmente por agregar em seus conselhos editoriais e consultivos pesquisadores de atestados méritos. Observa-se que tal constituição se deu em decorrência de estreita relação com o grupo de pesquisa nacionalmente consolidado, o HISTEDBR. Tal relação posiciona a revista desde seu início em um espaço importante tanto regionalmente como nacionalmente, precisando atenção aos dois vetores. As análises permitiram verificar o papel da internacionalização como vetor de algumas mudanças na revista. Também foi possível constatar que ao longo do tempo a revista se fortaleceu e assegurou seu espaço no campo científico, seja um espaço qualitativo devido a boa avaliação no Qualis-CAPES, A2, seja no espaço ocupado com a ampliação gradual da periodicidade e dos artigos publicados.
Mauro Mota
Authors: Amaral Tércio de Lima , Lins Aline Maria Grego
Published: April 2022

Formado pela Faculdade de Direito do Recife, Mauro Mota (1911-1984) foi um importante intelectual de Pernambuco no século 20. Ligado ao sociólogo Gilberto Freyre, sua obra é dinâmica e perpassa temas como questões sociais, poesias e reflexões sobre comunicação. Eleito em 1970, na cadeira ocupada por Gilberto Amado, o pernambucano contou com uma ampla rede de relacionamento para conquistar a imortalidade. Nosso artigo objetiva mostrar essas relações, renegadas em biografias, por meio da análise de três publicações nacionais brasileiras: O Estado de S. Paulo, O Globo e O Jornal, exercitando o poder de memória dos jornais.
Degeneração e eugenia nos discursos do I Congresso Médico de Pernambuco (1909)
Authors: Macario Beatriz Chianca , Borba Vicentina Maria Ramires
Published: April 2022

Este artigo apresenta parte do resultado de uma pesquisa de mestrado, que visou analisar os discursos do I Congresso Médico de Pernambuco, realizado entre os dias 25 de abril e 02 de maio de 1909, na cidade do Recife. Os discursos refletem ideias e teorias abordadas no início do século XX, e alguns deles demonstram um viés voltado para os estudos da degeneração e eugenia, tema proposto para este artigo. Utilizamos para análise alguns conceitos de Michel Foucault e de John Thompson, para explorarmos melhor os meandros do discurso.
The scope of ultra-diluted medicines in cases of Vitamin D deficient Hashimoto thyroiditis
Authors: Nazeema S. Sanofer , Kumar V. Sathish
Published: April 2022

Objectives:

The objectives of the study were to understand the scope of ultra-diluted medicines (homoeopathy) in treating cases of Hashimoto thyroiditis (HT) with low Vitamin D levels (determined by measuring the 25(OH) D3 levels) and assess the relationship between Vitamin D levels and HT.

Materials and Methods:

Twenty random patients presenting with symptoms of HT and deficient in Vitamin D were selected from the outpatient department of Sarada Krishna Homoeopathic Medical College and Hospital, Kulasekharam. After detailed case taking and repertorisation, remedies were prescribed. The Zulewski score was used to assess symptomatic improvement. Vitamin D and antithyroid peroxidase antibody (TPOAb) levels were recorded before and after intervention and subjected to statistical analysis.

Results:

After homoeopathic treatment, 90% of patients showed moderate to marked improvement in the Zulewski score (P = 0.00001), 85% showed improvement in 25(OH)D3 levels (P = 0.00001) and 75% showed marked reduction in TPOAb levels (P = 0.00208).

Conclusion:

In conventional treatment, levothyroxine is administered to patients with HT; moreover, as HT is an autoimmune disease, other systems are affected in the long term. We found that the individualised homoeopathic remedy is effective in treating the condition and improves the levels of 25(OH)D3 and TPOAb with no side effects. Patients with HT have low Vitamin D levels, but we found no exact correlation between the actual levels of 25(OH)D3 and TPOAb.
PECULIARITIES OF THE DEVELOPMENT OF THE TOBACCO AND TABLE INDUSTRY ON THE TERRITORY OF THE MODERN SUMCHINA AT THE BORDER OF THE XIX – XX CENTURIES
Authors: Hrytsenko Andriy , Svistun Olexander
Published: April 2022

The article is devoted to the analysis of the tobacco and shag industry, which developed on the territory of the modern Sumy region in the late XIX – early XX centuries. The authors draw attention to the peculiarities of the introduction of clear zoning in Ukraine on the cultivation of crops in general and tobacco in particular. It was also noted that the territory of Sumy region, as well as the whole north of Ukraine did not have powerful enterprises at that time, because the vast majority of tobacco was grown in the forest-steppe zone of Ukraine. In the course of the research, some pages of the development of tobacco enterprises in the territory of modern Sumy region were described. In particular, the launch of the first industrial enterprise on the Left Bank in Okhtyrka, which provided processing of tobacco products and the activities of a special office to provide the population with tobacco seeds in Romny. In addition, the article identifies periods with different rates of development of the tobacco and shag industry in the Ukrainian lands: growth (1861-1885), crisis and decline (1885-1900), active monopolization (1911-1914), having received a significant boost in development as a result of major reforms in the 1860s, the tobacco and shag industry was actively growing until 1885. After that, the Ukrainian lands are gradually reducing the area under tobacco and its gross harvest. The result was a decrease in the early twentieth century. the number of enterprises, which was accelerated by the reduction of markets for manufactured products and the introduction of the excise charter, according to which a small number were engaged in the purchase of leaf tobacco. Then, as a result of active monopolization of the domestic economy in the early twentieth century. the tobacco and shag industry, while reducing the number of enterprises due to their consolidation, was characterized by an increase in the number of manufactured products and the gradual introduction of mechanization into the production process.
FINDING A FORMULA FOR UNDERSTANDING AT THE VOLYN BORDER (20-30 YEARS OF THE ХХ CENTURY)
Authors: Davydiuk Ruslana
Published: April 2022

In defining the principles of the policy of memory in Ukraine and Poland today, the problem of understanding the attempts at interethnic reconciliation in the interwar period is significant. In the Second Polish-Lithuanian Commonwealth, they were associated with the ideas of members of the moderate part of the Polish intellectual elite, the political legacy of Marshal Józef Pilsudski and his supporters. The scientific article opens up the foundations of federalist policy and its specificity at the Volyn border. It has focused on the ideas of Polish intellectuals during the interwar period, their vision of the future of Ukraine, and Ukrainian-Polish relations. It was found that the practical implementation of the principles of Ukrainian-Polish cooperation and coexistence was embodied in the policy of Volyn governor Henryk Yuzevskyi. The ideas of prometheism, the «Volyn experiment» were shared by the Ukrainian political emigration leaders who consolidated around the figure of Symon Petliura. Some Polish intellectuals criticized the idea of the «Sokal border», an important component of «Volyn politics», noting that the separation of Galicia and Volynia only harms the interests of Poland. Despite the spread of ideas of interethnic tolerance among the representatives of the Polish moderate intellectual elite, the national policy of interwar Poland was marked by inconsistencies, contradictions, which ultimately led to deepening contradictions in society. Despite the spread of the ideas of the Polish-Ukrainian rapprochement, they have not been implemented in the Second Polish Republic.
THE INFLUENCE OF THE POLISH-SOVIET BORDER ON THE ECONOMY OF VOLYN’ VOIVODESHIP IN 1921-1939
Authors: Marchuk Volodymyr
Published: April 2022

The article attempts to outline the impact of the Polish-Soviet border on the economy of Volyn’ Voivodeship in the interwar twentieth century. The settlement of political and economic relations between Poland and the USSR had a negative impact on the possibility of economic development in the Volyn’ region while focusing on the markets of the USSR. It is established that in the period of 1921-1924 the economy of the region benefited from trade with Soviet Ukraine. During this period, illegal trade flourished in the territories adjacent to the border, which had a positive impact on the economy of the province. However, in the following period of 1925-1939, trade contacts between the Volyn’ Voivodeship and the USSR were reduced to a minimum. The geographical location of the Volyn’ Voivodeship on the border with the USSR and the economic potential of the region remained virtually untapped in favor of economic development. The strengthening of the border by the Border Guard Corps effectively isolated Volhynia from any contact with the Soviet side, thus making it impossible to use the existence of the border for the economic development of Volyn’ Voivodeship. Instead, the second period of 1925-1939 was characterized by the de facto complete elimination of border trade and the closure of the Polish-Soviet border.