bluuebunny/crossref_metadata_2025 huggingface dataset:
Вплив умісту імунологічних маркерів у внутрішньоочній рідині на прогресування вікової макулярної дегенерації після хірургічного лікування катаракти
Authors: Denisyuk O. , Mogilevskyy S.
Published: November 2023

Актуальність. Катаракта часто поєднується з віковою макулярною дегенерацією, але досі є сумніви щодо впливу факоемульсифікації на прогресування вікової макулярної дегенерації. Мета дослідження: проаналізувати вплив вмісту імунологічних маркерів у внутрішньоочній рідині на прогресування вікової макулярної дегенерації після хірургічного лікування катаракти. Матеріали та методи. Під спостереженням перебували 86 пацієнтів (93 ока) — 37 чоловіків і 49 жінок віком від 60 до 82 років, яким була проведена факоемульсифікація катаракти (ФЕК — імплантація м’якої інтраокулярної лінзи на апараті Infiniti фірми Alcon, USA). Оцінювали стадію вікової макулярної дегенерації (ВМД) за класифікацією Американської академії офтальмологів (AREDS, 2001). Обстежували пацієнтів через 1, 3, 6, 12 і 18 місяців після операції. Для статистичної обробки отриманих даних використовували програми Statistica 10 (StatSoft, Inc., USA) і MedCalc Statistical Software 18 (MedCalc Software bvba, Belgium). Результати. У 69,9 % очей із катарактою була наявна ВМД: рання і проміжна стадії (категорії 2 і 3 AREDS) були виявлені у 16,1 % випадків, пізня стадія (категорія 4.1 AREDS) — у 25,8 %, ексудативна форма (категорія 4.2 AREDS) — у 28,0 %. Гострота зору (ГЗ) до операції ФЕК відповідала стадії ВМД: була гіршою при категорії 4 AREDS. Для оцінки прогресування ВМД було розроблено індекс прогресування (ІПВМД), який характеризує середню швидкість змін клінічних проявів ВМД. З’ясовано, що у 12,9 % пацієнтів після ФЕК вперше встановлено діагноз ВМД; у цілому розвиток і прогресування ВМД після втручання відмічено у 33,3 % (ІПВМД > 0). Пацієнти без прогресування ВМД були на 6 років молодші за тих, хто мав прогресування (р = 0,001). При ІПВМД = 0,100 ум.од. прогресування ВМД відбувалося на ранніх термінах (3 місяці), при ІПВМД = 0,033 ум.од. — на пізніх (12 і 18 місяців). Після операції ФЕК ГЗ вірогідно збільшувалася, що залежало від початкової стадії ВМД (ГЗ була гіршою при пізній стадії та при вологій ВМД — категорія 4 AREDS) та прогресування ВМД (ГЗ була гіршою при ІПВМД > 0, а серед випадків прогресування — при ІПВМД = 0,033, тобто при пізньому прогресуванні). Висновки. Отримані результати обґрунтували необхідність проведення регресійного аналізу впливу вмісту імунологічних маркерів у внутрішньоочній рідині на прогресування ВМД після операції ФЕК на очах хворих на вікову катаракту. При однаковому пошкодженні (однаковий бал) випадки з подальшим прогресуванням ВМД відрізнялися вірогідно більшим початковим рівнем імуноглобулінових маркерів, особливо при максимальних значеннях бала за 25БШ. Це, можливо, пов’язано із впливом реактивності імунних маркерів на патогенез прогресування ВМД, що більшою мірою проявлялося при максимальному інтраопераційному пошкодженні.
Зв’язок розвитку макулярного набряку при діабетичній ретинопатії і цукровому діабеті 2-го типу з вмістом у крові Р-селектину
Authors: Rykov S.O. , Chugaev D.I.
Published: November 2023

Актуальність. При діабетичній ретинопатії (ДР), що ускладнена діабетичним макулярним набряком (ДМН) за умов цукрового діабету 2-го типу (ЦД2), встановлено важливе значення запальних і протромбогенних змін, серед яких найбільше значення мають посилення експресії молекул ендотеліальної адгезії, у тому числі P-селектину. Мета дослідження: встановити зв’язок розвитку ДМН при ДР різного ступеня та ЦД2 з вмістом у крові Р-селектину. Матеріали та методи. Дослідження включало 124 пацієнти (124 ока) із ЦД 2-го типу, у яких за класифікацією ETDRS виявлена легка (29 очей, 1-ша група), помірна або тяжка (35 очей, 2-га група) непроліферативна ДР та проліферативна ДР (31 око, 3-тя група); контрольну групу становили 29 очей без ЦД. Всім пацієнтам були виконані загальноприйняті офтальмологічні дослідження, спектрально-доменна оптична когерентна томографія (ОКТ) з визначенням центральної товщини сітківки (ЦТС, мкм). ДМН встановлювали при збільшенні ЦТС вище від значень нормативної бази даних по полях ETDRS програмного забезпечення спектрально-доменної ОКT. Вміст Р-селектину у крові визначали імуноферментним методом (Invitrogen ThermoFisher Scientific, USA). Для статистичних досліджень використано програмні пакети MedStat і MedCalc v.15.1 (MedCalc Software bvba). Результати. Вміст у крові Р-селектину при ДР та ЦД2 був вірогідно збільшеним порівняно з контролем (у 1,3 раза; p < 0,001), що при розподілі за стадіями зберігалося тільки для проліферативної ДР. Збільшення вмісту Р-селектину прямо корелювало з рівнем глікованого гемоглобіну та ЦТС. Тільки у пацієнтів з проліферативною ДР вміст Р-селектину за наявності ДМН був вищим, ніж без такого (у 1,2 раза; p < 0,001). При непроліферативній ДР вміст Р-селектину за наявності або відсутності ДМН не відрізнявся. Зв’язок збільшення вмісту Р-селектину з розвитком ДМН було підтверджено у регресійному аналізі (ВШ = 1,02; 95% ВІ 1,01–1,03). ROC-аналіз показав, що ця модель мала задовільні критерії тільки при проліферативній ДР (AUC = 0,85; 95% ВІ 0,68–0,95), що дозволило розрахувати межовий рівень прогнозу, який дорівнював 128,7 нг/мл (чутливість тесту 77,8 % і специфічність 69,2 %). Висновки. Результати дослідження підтвердили зв’язок між збільшенням у крові Р-селектину та розвитком ДМН при проліферативній ДР.
Effectiveness of Curriculum Based Industrial Training for Undergraduate Professional Courses
Authors: Kumar Amit
Published: November 2023

Education is one of the important needs of human life like food, cloth and house. It helps to develop and nourish overall human personality and socialization through physical and mental abilities. In similar manner, undergraduate courses play crucial role to built personnel and professional carrier in the world. Undergraduate courses such as B. Pharm. and B. Tech. (Biotechnology) are demanding in the present situation and are conducting by various government and private universities. According to the course curriculum of the universities, curriculum based industrial training for the undergraduate students are part of their courses. Therefore, the present study was designed, and conducted based on one month industrial training program for the undergraduate students by training department of Bharat Immunologicals & Biologicals Corporation Limited (BIBCOL), Bulandshahr, Uttar Pradesh, India as biopharmaceutical industry and also investigated for the effectiveness of the training program for students as participants belonging to the undergraduate courses from different academic institutions. Results of the study revealed that there was found significant impact of the designed and conducted training program on the participants through employing up-gradation in grade system A, B, C, & D after the successfully completion in BIBCOL as a bio-pharmaceutical industry.
PAQIA: The Relationship between Freshman College Students' Academic Performance and the Performance Analysis Quadrants, Interest, and Attitudes in Mathematics 11
Authors: G. Carbonel Loneza , Bayongan Arsenia , Carino Maribel , Daguasi Irene , Guzman Lamberto , Viloria Pommy
Published: November 2023

The teaching of the subject Mathematics in the Modern World is one of the new course in the first year college requires teachers to be a high tech teacher-leader or teacher-manager in their respective classrooms. This study surveyed freshmen college students in Math 11(Mathematics in the Modern) on their level of interest, attitudes, and academic performance and did a correlational approach to the gathered data. It also adopted the Performance Analysis Quadrant (PAQ) for employees by Jones (1993 to analyze the relationship of the factors like attitudes towards Mathematics and the level of performance indicated by the freshmen students in the areas of Mathematics. The results showed that:That most of the students have low interest and unfavorable attitude in Math 11(Mathematics in the Modern World) in which most of them have grades of 80 to 84%. The correlation of the level of interest in Math and academic performance is “positive moderate correlation”, while the attitude and level of interest in Math is” positive low or weak correlation”, and the attitude and academic performance is also “positive low correlation.” This implies that as attitude change, the academic performance also changes moderately. “The performance analysis quadrant revealed that most of the students have satisfactory performance but with unfavorable attitudes towards Math 11(Mathematics in the Modern World). Thus, the level of interest can contribute to the attitudes and the academic performance of the students in Math 11.
Exploring the Learning Experiences of Pioneer BS Environmental Studies Students of Kalinga State University
Authors: C. Cawayan Catherine , B. Tindo Juman Kevin , Lingbawan Shinju Cawis
Published: November 2023

The BS Environmental Studies course is required as a frontline for environmental care, protection, and management. In Kalinga State University, itproduced its pioneer BSES graduates in 2022. Individual interviews were employed in gathering the data—this employed phenomenology to qualitative research that focuses on the meaning of lived experience within a particular group. The information gathered was interpreted using the Creswell method. The study participants gained various meaningful experiences both during and after the training, it was discovered. After analyzing the data, the vast majority of the respondents' learning experiences were in a favorable direction.
Production and Marketing of Agroforestry Products in the Municipality of Rizal, Kalinga
Authors: L. Amoga Clarisa
Published: November 2023

This study was conducted to determine the status of production and marketing of agroforestry products in the Municipality of Rizal, Kalinga from February 10 to April 15, 2022. There were 53 respondents of the study. The descriptive statistics was used. Frequency counts, percent, means, ranks and correlation were used in the analysis and interpretation of data. Most of the respondents are Ilocano, males, married and at age bracket of 51 to 60 years old and had reached elementary level and supporting 5 and above family members. Most agroforestry farmers were cultivating their own sloping land with an area of 1 to 2 ha for more than 10 years and had used their own savings as capital in agroforestry farming. Majority were not affiliated with any organization. Many received financial assistance from government agencies to sustain their farming activities. Many farmers had generated an annual income of about ₱201, 000 and above from agroforestry farming. Generally, farmers’ house distance to their farms was 500 meters and below and a distance of 1 km and below from their farms to the market. Farm produced were mostly marketed through word of mouth and usually sold wholesale in local market. However, prices of products mostly fluctuate during peak and lean seasons. From the different agroforestry systems they have adopted, the highest income was generated from their agrocrops. Problems in production, marketing and financial aspects were rated slightly serious. Findings show a significant correlation between annual income and educational attainment, farm size, organizational membership, length of farming experience, distance of house from agroforestry farm and market, and the topography of the farm. Likewise, a significant correlation existed between the seriousness of problems encountered by the respondents to farm size and distance of agroforestry farms to market.
Level of Awareness on Social Media Platforms among the Employees of Kalinga State University Bulanao Campus
Authors: T. Aguilar Mark Joby , B. Bangat Rodemelia , G. Durian Annie Rose , C. Medrano Diana , C. Tuquilar Grethen , B. Cosidon Eileen
Published: November 2023

Social media platforms are ubiquitous nowadays, and have connected us in ways. We share information and updates with different social media platforms used. Teaching and school-related works are high-stress professions where it’s very important to used social media apps in which it leads to a more productive and collaborative atmosphere hence it is also good everyone’s psyche. Today’s world social media plays a vital role in connecting everyone’s life, and relationship through online communication, postings, and reactions. A descriptive normative survey method was undergone in data gathering procedures such as observation, survey questionnaires, and interviews. This study focuses on the identification of the participant's age and gender demographic profile and common active social media platforms used by the faculty and non-teaching staff in participating group discussion or interaction, determination of the level of awareness on the use of emoticons, common social media terminologies on social media across demographic groups, social media ethical practices and its implications towards their social relations. The work category were 141 Faculty and 30 Non-teaching staff members who are commonly working at one campus and evaluated thru 5 point Likert Scale. Most of the work category belong to the generations which are familiar on the use of computers and android cellphones where social media is easily accessible; Facebook and Messengeris revealed to be the most familiar social media plat forms for postings and sharing of both pictures and movies purposely for collecting social reactions while Messenger was used as communication media both for private and group communications. However, communication barriers are established among faculty and non-teaching staff members on the use of social terminologies and emoticons across demographical groups but generally social media implications has positive effect on social relations.
The Internal Efficiency of the College of Engineering and Information Technology
Authors: C. Gavino Zorayda , P. Mariani Mathew Jun
Published: November 2023

The study examined the College of Engineering and Information Technology's efficiency. Delivering better educational services within the limits of available resources is considered internal efficiency. It tried to assess the college's social, cultural, and economic subsystems. A survey was employed to gather data. The 150 respondents were college seniors. It received 35 responses from the ag and c & e departments. Forty-five replies came from civil engineering. Seventy-five (75) were from IT. These were chosen at random. Internally, the college's social, cultural, and economic subsystems were ranked and counted. The college's social subsystem is efficient. The teachers are far more capable. The communication flow is much better in college. The company is in a good mood. Each of the four functions is well stated. However, the ruling system is reasonable. CEIT's cultural component also works well. More detailed, achievable, and relevant to the school, community, and country's growth. They are found globally. The courses have been considerably enlarged, upgraded, and streamlined. Diverse instructional methodologies are employed. Co-curricular activities should be adequate, useful, and motivating. The same goes for teaching aids, reading materials, audio-visual equipment, and recorded video lectures. The college's economic structure is moderately efficient. The available resources are heavily exploited to create labs, libraries, and other facilities and train teachers.
Navigating Rover Using Arduino
Authors: Ranjani P Roopa
Published: November 2023

Abstract: The objective of the proposed system is to use Arduino to guide a rover. The connectivity will be the necessary electronic circuit. The PWM signal of a microcontroller powers the DC motors on the rover. The rover may be maneuvered along a straight path or any other path it chooses by manipulating each motor separately or in tandem. The rover is programmed with Arduino. The results of the system's implementation and testing in a real-world setting demonstrate its ability to precisely navigate through a variety of terrains and avoid obstacles. The suggested method may find use in search and rescue missions, environmental monitoring, and autonomous farming. Overall, navigating rover shows that creating a reliable and efficient rover navigation system is possible even with a commonly used programming language like Embedded C.
The Effects of Age-Mixing on Peer Cooperation and Competition
Authors: Liu Chao , LaFreniere Peter
Published: November 2023

This study may be the first to directly test the hypothesis that mixed-age interaction can increase cooperation and reduce competition among peers. Twenty pairs of preschoolers (ages 4-6) were observed twice in same-gender triads in a play situation involving a limited-resource: once in a same-age triad of preschoolers and once in a mixed-age triad that included a child approximately 5 years older. Children in mixed-age groups spent more time playing, were more equitable in sharing the resource, better organized and more cooperative, with smoother turn-taking and higher performance scores in the game. Children in same-age groups spent more time interfering with the game or disengaged. These findings demonstrate the potential benefits of mixed-age interaction in school settings.
In Praise of Polygamy
Authors: McGrew William C.
Published: November 2023

A review of the book “Love Times Three: Our True Story of a Polygamous Marriage” by Joe Darger, Alina Darger, Vicki Darger, Valerie Darger and Brooke Adams (2011).
You Can Look but You Cannot Touch: Male Behaviors Observed in Lingerie Stores
Authors: Moule Kimberly R. , Fisher Maryanne L.
Published: November 2023

Cultural theorists (e.g., Jantzen, Ostergaard, & Sucena Vieira, 2006) suggest that lingerie has shifted from being solely worn for the pleasure of men to being a way for women to claim their feminine identities. Due to these new feminine motivations, the role men play when they are with female companions who are shopping for lingerie is unclear. We argue the ambiguity of gender roles, as related to shopping for an item that represents both sexual attraction and feminine empowerment, may lead men to an approach-avoidance conflict. Observations were made of heterosexual couples shopping in either female clothing stores or lingerie stores. Male behaviors were compared for the two conditions, and significant differences were documented. Compared to clothing stores, men in lingerie stores were less likely to handle sexually provocative items but displayed visual interest, suggesting they desired to approach the merchandise (approach motivation) but refrained from engaging in physical contact (avoidance motivation). We argue that men’s behavior in lingerie stores represents classical approach-avoidance behavior.
On Aims and Methods of Facial Attractiveness Research: The Lasting Influence of Tinbergen (1963)
Authors: Stephen Ian D.
Published: November 2023

Tinbergen’s influential paper, On Aims and Methods of Ethology, has had a lasting impact on facial attractiveness research. While researchers rarely explicitly acknowledge the influence of Tinbergen’s ideas, the field has embraced evolutionary thinking in recent years. This focus on functional and phylogenetic explanations has led to the generation of hypotheses that, when tested, produce knowledge at all four explanatory levels – hypotheses about the survival value, in Tinbergen’s terms, of facial preferences have led to knowledge about the facial cues that are perceived as healthy and attractive. The focus on phylogeny as an important way of confirming predictions at the functional level has also led to the adoption of traditional ethological techniques of observation, as comparative and cross-cultural anthropological studies are brought into what is, at heart, an experimental science. The influence of Tinbergen’s ideas on facial attractiveness research is discussed with examples from the literature.
Naturalistic Observation in Public Settings: Applying for Institutional Review Board Approval
Authors: Hill Elizabeth M. , Monahan Mary N.
Published: November 2023

Collaborative interaction with Institutional Review Boards (IRBs) is an essential component of the research process. While the social scientific community clearly recognizes the ethical obligation to protect human research participants from harm, we are often uninformed about the specific procedures and operations of IRB committees. The ethical issues relating to naturalistic observational methods have been particularly laden with ambiguity, serving as a perpetual “gray area.” The present article provides an overview of federal guidelines regarding the ethics of naturalistic observation. The manner in which an IRB reviews a research proposal is described, emphasizing the perspective taken towards a study proposing naturalistic observation. Practical information regarding successful collaboration with IRBs is provided, using examples of studies that vary in their potential risks to volunteers.
Regional analysis of registered unemployment duration
Authors:   RANEPA, Moscow, Russian Federation, Maigur Anna ,   Gaidar Institute for Economic Policy, Moscow, Russian Federation
Published: November 2023

The paper estimates hazard risk models to find the determinants of the unemployment duration based on data from Russian employment centres for 2017–2021. Models with homogeneous and heterogeneous parameters by regions are built. It has been demonstrated that single parents and people with higher level of education need less time to find a job while pre-retirement age people need more. A high regional heterogeneity is revealed for both intercept and some coefficients’slope.
Job satisfaction in Russia: Wages, working conditions and promotion opportunities
Authors:   HSE University, Moscow, Russian Federation, Dubnovitskaya Anastasia , Furmanov Kirill ,   CEMI RAS, Moscow, Russian Federation
Published: November 2023

Using the RLMS-HSE data of Russian workers from 2002 to 2019 we investigate the relationship between job satisfaction and its components, videlicet satisfaction in pay, working conditions and promotion opportunities. We compare quantitative contribution estimates for each component. We found that satisfaction with working conditions is the major contributor to overall job satisfaction.
Finance and growth: Nonlinearity and structural shifts
Authors:   Financial University under the Government of the RF, Moscow, Russian Federation, Krinichansky Konstantin , Yurevich Maksim ,   Financial University under the Government of the RF, Moscow, Russian Federation
Published: November 2023

This study focuses on the nature and limits of the relationship between financial development and economic growth. The revealed non-linearity of this relationship is associated with a latent restructuring of mechanisms of economic financing, which took place during the financial and economic crisis of 2007–2009 and the years following it. The crisis, which hit the banking sector the hardest, simultaneously increased the role of the stock market. Using the two-step system GMM approach and the structural breaks algorithm, it is shown that the economic growth rates after 2010 are significantly related to stock market indicators, rather than the credit depth ones commonly used in finance-­growth models
Estimating the effect of Russia’s development policy in the Far Eastern region: The synthetic control approach
Authors:   Eastern State Planning Center, Khabarovsk, Russia, Goryunov Alexander , Ageshina Elena ,   Eastern State Planning Center, Khabarovsk, Russia, Lavrentev Igor ,   Eastern State Planning Center, Khabarovsk, Russia, Peretyatko Polina ,   Eastern State Planning Center, Khabarovsk, Russia
Published: November 2023

In 2014 Russian government enacted an ambitious policy of the “accelerated development” of the Far East. A number of special legal provisions, tax incentives and investment programs have been introduced as part of that policy. Several studies have since attempted to estimate the impact of the policy on the region’s economy using intertemporal or interregional comparisons of outcomes, with most studies finding there to be no significant impact. We use the synthetic control method to arrive at a quantitative estimate of the policy’s effect on the real per capita GRP of the Far East in 2014–2019. Using a pool of 59 regions to construct a counterfactual baseline and controlling for the overall level of higher education, share of the raw materials industry, share of investment in GRP and the share of working age population, we estimate that the policy had resulted in the creation of around 93 billion rubles of additional GRP in the Far East during 2014–2019. We also propose a procedure for estimating the statistical significance of the result in the case when Fischer’s Exact Test, which is normally used with synthetic controls, is not applicable due to the composition of the treated object. Using our proposed procedure, we find that our estimate of the policy’s effect is statistically significant at the 5% level.
Impact of COVID‑19 on household consumption in Russia
Authors:   HSE University, Moscow, Russia, Voytenkov Valentin , Demidova Olga ,   HSE University, Moscow, Russia
Published: November 2023

This paper investigates the impact of the COVID‑19 pandemic on household consumption patterns in Russia. We use household budget survey data, modelling the impact of household socioeconomic characteristics on consumption patterns. Additionally, we account for the regional heterogeneity of the severity of the quarantine measures. The results indicate a quantitative change in household consumption structure, but consumers’ behaviour patterns remain unchanged.
Strategi Komunikasi Krisis BKN terhadap Kecurangan Seleksi Calon Aparatur Sipil Negara Tahun 2021
Authors: Raharji Najib Muhammad Arya
Published: November 2023

The selection process for Candidates for Indonesia Civil Servants (CASN), which is followed annually by millions of applicants, has never been without the issue of fraud. The peak occurred in 2021 where the issue of fraud developed and caused a crisis at the BKN as the organizer of the CASN selection. This study aims to analyze the crisis communication strategy implemented by BKN in dealing with this CASN selection fraud crisis. The type of research in this study was qualitative with a case study research type with 4 informants who were BKN crisis management teams using purposive sampling. The results showed that BKN uses 9 stages, namely: Crisis identification, Situation analysis, Communication goals, Audience identification, Determining message content, Selection of media and communication activities, Determination of communicators, Implementation of communication activities, and Evaluation. The findings of this study indicate that the nine stages implemented by BKN are able to handle crises effectively and maintain a positive image of the organization.
KONSEP HUSN AL-KHULUQ MENURUT AL-GHAZALI DAN RELEVANSINYA TERHADAP SIKAP MODERASI BERAGAMA
Authors: Abdul Ghofur
Published: November 2023

This study aims to find out the concept of “husn khuluq” according to Al-Ghazali in the book of Ihya' Ulumuddin and see its relevance to the concept of “religious moderation.” This study is conducted using the library research method by collecting and analyzing all aspects related to the theme. This article shows that the concept of husn al-khuluq requires a person’s inner aspect. The concept of religious moderation and the concept of husn al-khuluq have the same emphasis, namely al-i’tidal (fair, in the middle). Someone who has husn al-khuluq is already moderate. According to al-Ghazali, there are at least four important points that become substantial basics that form good morals (husn al-khuluq), namely al-Hikmah, ash-Syaja’ah, al-Iffah, and al-‘Adlu. Some of these things, if done with full confidence, can form a strong character for a person in their religious moderation.
Back to the future: Using herbarium specimens to isolate nodule associated bacteria
Authors: Petipas Renee Helen , Antoch Amanda A. , Eaker A.N. , Kehlet-Delgado Hanna , Friesen Maren
Published: November 2023

Herbarium specimens are increasingly being used as sources of
information to understand the ecology and evolution of plants and their
associated microbes. Most studies have used specimens as a source of
genetic material using culture independent approaches. We demonstrate
that herbarium specimens can also be used to culture nodule-associated
bacteria, opening the possibility of using specimens to understand
plant-microbe interactions at new spatiotemporal scales. We used
historic and contemporary nodules of a common legume, Medicago lupulina,
to create a culture collection. We were able to recover historic
bacteria in 15 genera from three specimens (collected in 1950, 2004, and
2015). This work is the first of its kind to isolate historic bacteria
from herbarium specimens. Future work should include inoculating plants
with historic strains to see if they produce nodules and if they affect
plant phenotype and fitness. Although we were unable to recover any
Ensifer, the main symbiont of Medicago lupulina, we recovered some other
potential nodulating species, as well as many putative growth-promoting
bacteria.
Fragterminomics: extracting information on proteolytic processing from shotgun proteomics data processed by FragPipe
Authors: Cosenza-Contreras Miguel , Seredynska Adrianna , Pinter Niko , Brombacher Eva , Dinh Thien-Ly Julia , Bernhard Patrick , Rogg Manuel , Liu Junwei , Willems Patrick , Stael Simon , Huesgen Pitter , Kuehn E. Wolfgang , Kreutz Clemens , Schell Christoph , Schilling Oliver
Published: November 2023

State-of-the-art mass spectrometers combined with modern bioinformatics
algorithms for peptide-to-spectrum matching (PSM) with robust
statistical scoring allow for more variable features (i.e.,
post-translational modifications) being reliably identified from
(tandem-) mass spectrometry data, often without the need for biochemical
enrichment. Semi-specific proteome searches, that enforces a theoretical
enzymatic digestion to solely the N- or C-terminal end, allow to
identify native protein termini or those arising from endogenous
proteolytic activity (also referred to ‘neo-N-termini’ analysis or
‘N-terminomics’. Nevertheless, deriving biological meaning from these
search outputs can be challenging in terms of data mining and analysis.
Thus, we introduce Fragterminomics, a data analysis approach for the (1)
annotation of peptides according to their enzymatic cleavage
specificity, (2) differential abundance and enrichment analysis of
N-terminal sequence patterns, (3) visualization of neo-N-termini
location, and (4) mapping neo-N-termini to known protein processing
features. We illustrate the use of Fragterminomics by applying it to
tandem mass tag (TMT)-based proteomics data of a mouse model of
polycystic kidney disease and assess the semi-specific searches for
biological interpretation of cleavage events and the variable
contribution of proteolytic products to general protein abundance. The
Fragterminomics approach and example data are available as an R package
at https://github.com/MiguelCos/Fragterminomics.
Wsparcie zrównoważonego rozwoju wsi i rolnictwa środkami z funduszy strukturalnych w latach 2004-2008
Authors: Kołyska Justyna
Published: November 2023

Zrównoważony rozwój stanowi obecnie nieodłączny element polityki ekologicznej i społeczno-ekonomicznej a także różnych strategii rozwoju społeczno-gospodarczego. Celem artykułu było przedstawienie sposobów wspierania zrównoważonego rozwoju wsi i rolnictwa w Polsce oraz wielkości środków finansowych przeznaczonych w latach 2004-2008 na realizację tej koncepcji w ramach funduszy strukturalnych Unii Europejskiej. W artykule omówiono rozkład środków finansowych na poszczególne programy, priorytety i działania a także poziom wykorzystania środków w poszczególnych województwach Polski.
Numerical simulation and application of argon blowing from tundish cover for bloom continuous casting
Authors: Wu C.-H. , Li Y. , Liu Y-D. , Xie X. , Wu G.-R. , Zhang M.
Published: November 2023

During the continuous casting process, the residual oxygen in the tundish can be significantly reduced by argon blowing from the tundish cover (ABTC). As a result, the effect of protective casting can be obviously improved, which helps to reduce the reoxidation of molten steel in the tundish. In the present work, numerical models for the ABTC of a six-strand continuous casting machine were established and verified by the measured oxygen mass fraction in the tundish during the ABTC. The results indicate that the best conditions for ABTC are to install the argon pipes on either side of the tundish cover holes, seal the baking holes, and keep the stopper rod holes open. The argon flow rate should be ?120 m3/h during the period of empty tundish and ?60 m3/h during the period of normal casting. Based on the calculation results, industrial testsof ABTC were carried out. The results indicated that the increased nitrogen content in steel(?w[N]) decreased by 21.5% from 8.78?10- 6 to 6.89?10-6 , from the end of RH to tundish, and the amount of inclusions except for MnS in bloom (scanned size: 8 mm ? 8 mm) decreased by 21.3% from 13.43 to 10.57, and the average size of inclusions decreased by 19.0% from 9.27 ?m to 7.51 ?m.
Microstructural, mechanical and thermodynamic properties ınvestigation of the novel rare earth-free multicomponent Mg-15Al-8Ca-3Zn-2Ba alloy
Authors: Türe Y.
Published: November 2023

There has been a significant increase in research and development efforts to meet the growing demand for environmentally friendly magnesium (Mg) alloys. Studies are currently exploring different combinations of alloying elements to meet the demanding specifications. The aim of this study was to examine the usability of the elements aluminum (Al), calcium (Ca), and zinc (Zn) together with barium (Ba), and to investigate the mechanical and thermodynamic properties of the resulting multicomponent alloy system. SEM and hardness tests were used to examine the microstructural and mechanical properties of the Mg alloys. In the SEM analysis, the alloy was determined to consist of an ?-Mg matrix, a block-like compact structure containing Ba (Mg17Ba2), a regional eutectic structure (Ca2Mg6Zn3), and independently growing lamellae (Al2Ca). The general hardness analysis results of the alloy, measured by Brinell and Vickers tests, were determined to be ~77 and ~82, respectively. The indentation test also revealed that the stress transfer to the Al2Ca laves phase is possible, depending on the orientation of the slip plane between the matrix and the Al2Ca phase. It was also observed that cracks that developed on the intermetallic Mg17Ba2 phase in the indentation test were only formed in the high-stress regions of the structure, and their propagation was limited. According to the thermodynamic analysis, the ?Hmix value is -2.73 kJ/mol, the ?Smix value is 5.95 J/molK, the ? value is 34%, the ?? value is 0.14, and the ? value is 2.03. The obtained thermodynamic data were found to be compatible with the microstructural development of the alloy.
FACE RECOGNITION METHODS IN VIDEO SURVEILLANCE SYSTEMS USING MACHINE LEARNING
Authors:   Lviv Polytechnic National University, Mrak M.
Published: November 2023

The article is dedicated to the investigation of face identification methods and aims to determine the most suitable one for a security system based on facial recognition from surveillance cameras. The time costs of these methods and their robustness against geometric scale distortions and rotations in various planes have been analyzed. Custom datasets have been generated for experimentation purposes. Special attention has been given to striking a balance between the speed and accuracy of the examined methods for their utilization as the initial stage of a security system based on facial recognition in a video stream. The conducted research has revealed that the most effective methods are RetinaFace-MobileNet0.25, FaceBoxes, SCRFD500MF, and CenterFace; RetinaFaceResNet125, DSFD, and RetinaFaceMobile0.25 which are resilient to facial rotations. Furthermore, when selecting the most optimal facial recognition method for application within a security system, the presence of informative facial parameters was taken into account, as well as the fact that the recognition methods used in the subsequent stage have their limitations concerning resilience to affine transformations.
INVESTIGATION OF DISTRIBUTED MATRIX FACTORISATION EFFICIENCY IN THE INDUSTRIAL SYSTEMS
Authors:   Lviv Polytechnic National University, Hordiichuk-Bublivska O.
Published: November 2023

The processing of big data is an exceedingly urgent challenge in the functioning of modern information systems. The latest information technologies must be employed to collect, store, and analyze vast amounts of information. Intelligent data processing systems were implemented in numerous fields, particularly in the industry. Smart industrial systems also utilize data from various devices, enabling automated management processes and network component analysis. A prime example of an intelligent industrial system is the smart grid, which efficiently distributes electricity to users by considering demand, network parameters, load, etc. Processing large amounts of information necessitates the use of machine learning methods and mathematical data analysis. Matrix factorization serves as an exemplary technique for transforming information into a more convenient form for further processing, establishing relationships between elements, and optimizing outcomes. In particular, the SVD (Singular Value Decomposition) and Funk-SVD algorithms are employed to address big data processing challenges, and they were discussed in this work. The key features of processing large data volumes in industrial smart grid systems were analyzed in the paper. The advantages of distributed computing for more efficient information analysis were identified. The recommendation algorithms that enable faster and more accurate processing of extensive data were explored in the study. Specifically, the SVD and Funk-SVD algorithms, used in recommendation systems for large data processing, were examined. A method of distributed matrix factorization to provide recommendations to smart grid system users was proposed in the paper. This approach involves the exchange of public data between devices and the local processing of private data. The advantages of this distributed model include flexibility in adjusting parameters, improved calculation accuracy through result exchange between nodes, high data processing speed, and scalability were identified. The conclusion that the proposed method can be effectively used in recommendation systems within the smart grid context, enhancing automated management processes and resource distribution was exclaimed.
METHODOLOGY OF BUILDING PROTECTED SPECIAL PURPOSE INFORMATION COMMUNICATION NETWORKS
Authors:   National University of Defense of Ukraine named after Ivan Chernyakhovsky, Zakharzhevskyi O.
Published: November 2023

This article is devoted to the solution of a new topical scientific task regarding the formation of a methodology for the construction of prospective secure special purpose information communication networks. The construction architecture was analyzed and a new classification of information communication networks by functional decomposition was presented for the first time. The content of the structural components of the network at the level of "network", "system", "information communication networks" has been determined. A new functional description of the image of a promising network and its quality has been developed. Based on the analysis of international and special standards, the first proposed decomposition of the scope of application in information communication networks of special purpose networks is presented. New scientific approaches to the design of special-purpose protected information communication networks are proposed, which include functional-structural and structural-functional approaches. According to the proposed approaches, the work presents a list and description of models for building special-purpose information communication networks. Their content, application limitations, advantages and disadvantages of individual models are revealed. A new scientific task of designing a promising special purpose secure information communication network based on public access channels was formed and its general description was given.
THE STATE VECTOR OPTIMAL ESTIMATES FOR DISCRETE STOCHASTIC SYSTEMS WITH UNCERTAIN PERTURBATIONS AND NOISE
Authors:   Vinnytsia National Technical University, Volovyk A.
Published: November 2023

Assessment of the dynamic systems state is widely used in various areas of technical activity. In practice, the most well-known and common methods of estimation are the methods of the Kalman filter and Luenberger observers. Most of the results known in the scientific literature for constructing estimates of the dynamic systems state in the presence of acting uncontrolled disturbances and noise are associated with stationary systems. The insensitivity of such estimates to the influence of accompanying uncontrolled perturbations is ensured by the introduction of certain restrictions that are imposed on a number of system matrices, and their optimality is achieved by minimizing the estimation errors covariance matrix trace due to those degrees of freedom that remained after the separation procedure was performed. The aim of the work is to develop a filter capable of generating state vector optimal estimates of a stochastic linear system with changeable parameters that are insensitive to the influence of uncontrolled inputs. In this case, the conditions that guarantee the convergence of the estimates obtained must be easily verifiable. The goal is achieved by using a one-to-one transformation of the equations of systems, followed by the application of the Kalman filter. The O'Reilly functional observer is used as the specified transformation. An example is given that illustrates the effectiveness of the proposed filter.
RESEARCH AND DEVELOPMENT OF A HIGH-PRECISION DIRECTION FINDER FOR RADIO EMISSION SOURCES DETECTING
Authors:   Lviv Polytechnic National University, Fabirovskyy S. , Storozh V. , Solomko A.
Published: November 2023

This article is devoted to solving the problem of developing a high-precision radio direction finder for radio emission sources detecting. The paper substantiates the relevance of these devices to date and identifies areas of application. Two versions of the direction finder have been developed - with an operating bandwidth of 100 MHz and a wide-range version with an operating band of about 2000 MHz. Two layouts of these radio direction finders were made, and full-scale tests of individual units of devices and devices as a whole were carried out. The test results allow us to conclude that the developed layouts provide a direction finding characteristic curvature of 8 dB/degree, which is sufficient when using weakly directional antennas. At the end of the work, certain features of the functioning of the devices and recommendations for their improvement are presented.
The Effect of The Diorama Media-Assisted Core Type Operative Learning Model on Student Learning Outcomes
Authors:   Departement of Geography Education, Teacher and Training Faculty, Universitas Syiah Kuala, Banda Aceh, Indonesia Indonesia, Wati Julita , Aziz Dazka , Novia Zalmita
Published: November 2023

This study aims to determine the effect of the CORE type cooperative learning model assisted by diorama media on learning outcomes in hydrofer material at SMA Negri 5 Banda Aceh. This type of research is Quasi Experimental Design. The population of this study were all students of class X IS SMA Negeri 5 Banda Aceh. Sampling was done by purposive sampling technique, taken from class X IS 3 (experimental class) of 29 students and class X IS 2 (control class) of 29 students. Data collection techniques by giving tests to students, namely pre-test and post-test. Data processing techniques using the t test. The results of data processing obtained tcount = 5.12 and ttable = 1.67. According to the test criteria, Ha is accepted if tcount > ttable at a significance level of 5% and dk = (n1 + n2 – 2). Based on the calculation results obtained tcount > ttable or 5.12 > 1.67 it can be stated that Ha is accepted, so it can be concluded that there is an influence of the CORE type cooperative learning model assisted by diorama media on learning outcomes in SMA Negeri 5 Banda Aceh.
Remote Monitoring, Control and Data Visualization for a Solar Water Pumping System
Authors: Ahmed Omair , Iqbal M. Tariq
Published: November 2023

Access to clean water is a significant challenge in many regions, including Sukkur, Pakistan. The effective management of water resources is a critical challenge, particularly in areas with limited access to surface water sources. This paper presents a remote monitoring of water pumping system designed to address water distribution challenges in Sukkur, Pakistan. The system utilizes a combination of hardware components, including Arduino Uno, Raspberry Pi 2, ultrasonic sensor, and GSM modules, to enable remote monitoring, control, and data visualization. The system architecture incorporates Node-RED, a powerful flow-based programming tool, to facilitate data communication, storage, and visualization. To enable remote monitoring and control, users can send SMS commands to the Arduino Uno, connected to the GSM module, to query the system's status and control the pump's operation. Additionally, a mobile application developed using the MIT App Inventor platform allows users to interact with the system, visualize real-time and historical data, and receive updates on water levels and pump status. The Raspberry Pi 2 serves as a server and cloud storage for the system.