bluuebunny/crossref_metadata_2025 huggingface dataset:
The Investigation of the Uneven Volatility, Risk, Return Distribution Problem on the Modern Russian Stock Market
Authors: Kotov Aleksandr , Tolkachev I.
Published: March 2022

The article analyzes problems and features of the Russian stock market at the current stage. Particular attention is paid to the problems of excessive levels of risk and volatility, as well as the discrepancy between the volatility and risk distribution to the distribution of the securities expected yield. The authors also consider the imbalance in the intersectoral context based on the changes dynamics in the profitability of the Moscow Stock Exchange's industry indices. The relationship between liquidity and volatility is also analyzed. In the course of the study, stocks are distributed by industry using the industry classifier of the Moscow Stock Exchange, intra-industry analysis is carried out on the basis of the oil and gas, financial and metallurgical companies stocks. Based on the conducted research, the key problems and their impact on the trading and market analysis methods used by investors and traders are identified. Recommendations on the application of these methods are given.
How AI will transform the cyber security industry
Authors: Gurtu Anurag
Published: March 2022

In today’s digital world, one of the most common, as well as concerning, issues is the challenge posed by cyber attacks. Organisations around the world use all types of techniques to combat these threats. And one of the most powerful weapons available, which has the potential to completely transform the cyber security industry, is artificial intelligence (AI).
Bulletproof hosting and the Magecart threat
Authors: Libeau Fabian
Published: March 2022

Magecart skimming groups have been targeting online retailers since 2016. However, to truly understand them, it’s important to understand the tools of the trade. The Inter skimmer kit is one of today’s most common digital skimmer solutions. However, a hallmark of widely used skimmers is their propensity to evolve as more actors use and tweak them to suit their unique needs and purposes.
Analysis of factors affecting Korean Medicine utilization of multicultural family members
Authors: Song Minsun , Choi Chanhun , Kim Dongsu
Published: March 2022

Objectives: This study aimed to analyze the Korean medical utilization and Korean medical expenses by characteristics of multicultural family members to investigate whether it affects Korean medical utilization.Methods: This study utilized The Korea Health Panel data in 2018, with 238 final participants. We performed a t-test and ANOVA on the difference between Korean medical utilization and Korean medical expenses according to Anderson’s Model of Health Service Utilization variables. Logistic regression analysis and generalized linear model analysis were conducted to analyze Korean medical utilization factors.Results: The Korean Medical utilization was 12.61% among the multicultural family members. As a result of regression analysis, the female had high Korean medical utilization(p=.008), and rural area residents had low utilization(p=.017). Korean medical expenses were high when they were female or married. Including the utilization of western medical services by outpatients, Korean medical expenses were high when they were female or outpatients who received western medical services.Conclusions: As a result of this study, the factors influencing Korean medical utilization were gender and residence area. There were differences in Korean medical expenses depending on western medical services use or gender. Therefore, it is necessary to use these factors to expand the Korean Medical utilization by multicultural family members, and research of the Korean medical utilization by disease is needed.
Review on the effect of acupuncture on Parkinson's disease over the last 5 years
Authors: Kim Seo-Young , Lim Young-Woo , Kim Eunjoo , Park Seong-Uk
Published: March 2022

Objectives: The objective of this study was to summarize clinical studies conducted over the last five years that investigated the effect of acupuncture on Parkinson's disease and to propose a better process of study.Methods: Research Information Sharing Service (RISS), Korea Studies Information Service (KISS), Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase, and China National Knowledge Infrastructure (CNKI) were systemically searched for clinical trials that had investigated the effect of acupuncture on the course of Parkinson's disease from May 2016 to April 2021.Results: A total of 23 studies met all the inclusion criteria. In most reports, acupuncture had significant positive effects on the course of Parkinson’s disease. Furthermore, there were no serious adverse events associated with acupuncture in any of the studies. In addition to the acupuncture methods that showed effectiveness in previous studies, various types of acupuncture have been used to treat sub-symptoms of Parkinson's disease. The outcome measures were subdivided through individual symptom evaluation and mechanical analysis. Follow-up assessments were also performed to analyze the continuous effect.Conclusion: In the clinical studies conducted over the last five years, many studies investigated the various types of acupuncture used to treat Parkinson’s disease and the segmentation and diversification of outcome measures focusing on individual symptoms, and a new approach for excluding placebo effects through follow-up studies has been made. Further attempts like these are needed to overcome methodological flaws in studies on the effects of acupuncture on Parkinson's disease.
A Review of the Korean Traditional Medicine Treatment for Meniscus Injury
Authors: Han Sihoon , Oh Taeyoung , Oh Minseok
Published: March 2022

Objectives: The purpose of this study was review the current clinical studies about the effect of Korean traditional medicine treatment for meniscus injury.Methods: Clinical studies on Korean traditional medicine treatment of meniscus injury were searched through 11 online databases. We analyzed the authors, publication year, country, study design, subjects, treatment methods, treatment effects, evaluation tools and adverse events of the selected studies.Results: 23 studies which included 9 randomized controlled trials, 8 case reports, 4 retrospective observational studies, 2 non-randomized controlled trials were selected through the databases. A total of 9 Korean traditional medicine treatments were used, among them, acupuncture treatment was the most used. The most commonly used outcome was effective rate.Conclusions: Through this study, we could confirm that Korean traditional medicine is an effective treatment for meniscus injury. It was suggested that various clinical studies on the effects of Korean traditional medicine for meniscus injury are needed and it is necessary to establish more scientific evidence through studies with a high level of evidence.
Performance Assessment and Sensitivity Analysis of a Computer Lab Network Through Copula Repair with Catastrophic Failure
Authors: Poonia Praveen Kumar
Published: March 2022

The advent of copula distribution by Gumhel-Hougaard family spurred a new direction of research in multi-state complex engineering systems and is widely applied in various series-parallel systems. Considering this aspect, in this paper we study various reliability measures of a complex system consisting of eight identical computer labs as star topology working under 5-out-of-8: G policy, two different centralized data base servers working under 1-out-of-2: G policy, and a switch in series configuration. Failure rates of all the units are assumed to be constant and follow exponential distribution, while repair supports general distribution and copula distribution. The objective of this paper is to evaluate availability of the system, reliability of the system, mean time to failure and expected profit analysis by choosing arbitrary values of the parameters in a way that numerical solutions can be obtained systematically in a reasonable computational time. The problem is modelled using supplementary variable technique, Laplace transform and copula repair. We highlight the use of copula repair, while identifying the factors for improvement and future directions of work.
La llengua catalana a Mallorca. Els escrits (socio)lingüístics publicats a la revista Lluc (1968-1999)
Authors: Calafat Vila Rosa M.
Published: March 2022

La revista Lluc a partir de la segona meitat del segle XX es convertiria en una plataforma de caràcter cultural, atenta i crítica als esdeveniments sociolingüístics de la Mallorca d’aquell temps. El període d’estudi que abordam comprèn des del gener de 1968, data d’inici d’una nova etapa amb el terme Països Catalans entre les seves pàgines, fins al 1999. La ideologia de la publicació se centraria en la socialització d’actituds lingüístiques positives al voltant de la llengua i la cultura catalanes, amb un relat favorable a la funció discriminant del català. Aquest estudi analitza des de la disciplina de la Sociolingüística els discursos presents en el articles d’opinió de les firmes més destacades de la intel·lectualitat i, fonamentalment, en els editorials que al voltant de les funcions lingüístiques de la societat i de les funcions socials de la llengua catalana a les illes constitueixen els continguts de Lluc. L’estudi es divideix en dos blocs referents a les opinions a l’entorn de l’estatus de la llengua, la seva vehiculació en els àmbits de l’ensenyament, els mitjans de comunicació i l’Església; i sobre el corpus, la variació geolectal aplicada a la norma referencial, seguint el mestratge de Francesc de B. Moll.
L’ensenyament del castellà a Catalunya a través de la premsa: Els articles pedagògics del mestre Gironí Salvador Genís i Bech (1841-1919)
Authors: Gallardo Richards Emma
Published: March 2022

L’ensenyament del castellà a les regions de l’estat on no es tenia el castellà com a llengua nativa va esdevenir una de les qüestions que va marcar les reivindicacions del magisteri català durant el segle XIX i part del XX, ja que segons la legislació vigent es pretenia escolaritzar a l’alumnat en un idioma oficial del qual no en tenien coneixements. A partir de tres sèries d’articles que es van publicar a la premsa durant les primeres dècades del segle XX, titulats «Llengua y ensenyansa» (1903), «La llengua docent a les escoles de Catalunya» (1917) i «El plet lingüístic a les nostres escoles» (1918), s’aprofundirà en la visió del mestre gironí Salvador Genís sobre el paper que havien de tenir el català i el castellà en el sistema escolar de Catalunya i la seva proposta per facilitar l’ensenyament de la darrera llengua.
Depositional evolution and models for a deep-lacustrine gravity flow system in a half-graben rifted sag, Beibuwan Basin, South China Sea
Authors: Li Yuan , Wang Hua , Zhang Guotao , Lin Song
Published: March 2022

The Paleogene Liushagang Formation is part of the Fushan Sag, a continental lacustrine basin located at theSoutheastern margin of the Beibuwan Basin, South China Sea. Further understanding of the deep-water gravityflow deposits in this formation will be conducive to lithologic reservoir exploration in the sag. In this study,three members of the Liushagang Formation, SQEls3 SQEls2 and SQEls1, from old to young, are used withcore observation, well log data, and three-dimensional seismic data to identify four deep-lacustrine gravity flowlithofacies including their vertical and lateral relationships within the depositional system. The results are thenused to establish a deep-water gravity flow depositional model. Four types of gravity flow lithofacies developed inthe sag: sandy debrite, turbidite, sandy slump, and bottom-current deposits. Sand-rich sub-lacustrine fan depositswith typical turbidite channels were developed mainly in the western depression, whereas distal isolated lobesformed by sandy debrite flow deposits occurred mainly in the eastern depression. The results obtained in this studywill be helpful in the research of gravity flows in similar continental lacustrine environments.
Aportes para una bioética crítica
Authors: Arias Krause Juan Ignacio
Published: March 2022

En una primera instancia, el artículo presentará una tesis general sobre la Bioética, dimensionando el campo de tensiones que le subyacen, como la relación de la técnica con las costumbres sociales. Esta consideración del problema bioético procura ampliar el ámbito señalado por la Bioética fundamental (entendida en un contexto clínico), para especificar el carácter crítico que se debería encontrar a la base de su reflexión. Finalmente, se establecerá un vínculo desde esta base con el campo clínico, donde la Bioética ha tenido su más importante aplicación a fin de resaltar su valor social.
Consideraciones éticas sobre CRISPR/Cas9: Uso terapéutico en embriones y futura gobernabilidad
Authors: Ferreyra Karen Ayelén
Published: March 2022

La técnica de edición genética CRISPR-Cas9 ha hecho una revolución dentro de la ciencia y también ha generado discusiones sobre su uso en humanos, tanto a nivel de seguridad como ético y político. En este trabajo, argumento que no es posible realizar ediciones genómicas para un uso terapéutico de la técnica CRISPR-Cas9 en embriones con enfermedades monogénicas que se convertirán en futuros niños o niñas hasta que no se garantice mayor seguridad y eficacia. Para ello, considero que debe haber un balance entre la prevención en su uso terapéutico y su uso en investigación. En primer lugar, explico los diferentes posibles usos de la técnica CRISPR-Cas9 diferenciando su uso terapéutico, (práctica validada y práctica no validada); su uso para mejoramiento y su uso en investigación. En segundo lugar, analizo cuales son los riesgos de realizar ediciones genómicas para uso terapéutico. Además, enumero una serie de consideraciones éticas a tener en cuenta en el futuro en caso de que esta técnica sea aprobada. En tercer lugar, evalúo los consensos internacionales dados hasta el momento y describo el caso de Argentina, su prohibición y los problemas que genera a la hora de hacer investigaciones. En cuarto lugar, analizo las diferentes alternativas reproductivas existentes y realizo un análisis de riesgo/beneficio para su posible uso. Por último, evalúo una posible objeción a mi trabajo explicando que este no contempla la libertad reproductiva de los futuros padres/madres. En respuesta a ello, considero que se genera un conflicto entre los principios de autonomía y no maleficencia.
Una aproximación a las dimensiones estática y dinámica de la voluntad procreacional a partir de la reproducción asistida post mortem
Authors: Geri Leonardo
Published: March 2022

El objeto del presente artículo es contribuir al desarrollo conceptual de la voluntad procreacional, en tanto elemento que legitima los actos médicos propios de las técnicas de reproducción humana asistida y que determina la filiación resultante. El problema de investigación refiere a la disparidad que se advierte tanto en la legislación española como en la catalana entre la reproducción asistida heteróloga y la reproducción asistida post mortem: Mientras en el primer caso el consentimiento informado es suficiente a los términos de la filiación, en el segundo supuesto se exige también la concurrencia del dato genético. El mismo esquema se presenta en Argentina a partir de la normativa proyectada sobre reproducción post mortem. La hipótesis sostenida es que ello posee una razón bioética suficiente, consistente en la distinción entre la dimensión estática y la dimensión dinámica de la voluntad procreacional, y en el recurso al elemento genético ante la ausencia anticipada de la segunda.
Grado de información percibida por los tutores legales en el Consentimiento Informado en el servicio de Neumología y Alergia Infantil
Authors: Jang Dah Tay , Oishi Konari Miriam Natsuki , Costa Daalmans Irene , Mazón Ramos Ángel
Published: March 2022

Introducción: Existe escasa información sobre el grado de información percibida por los tutores legales en el Consentimiento informado (CI) en el ámbito pediátrico. Objetivos: Evaluar el grado de información percibida por los tutores legales en el CI de pruebas de provocación en Alergia Pediátrica. Métodos y Materiales: Estudio descriptivo, observacional y transversal de valoración de información mediante cuestionario, en el período de abril-mayo de 2021. El cuestionario fue desarrollado por el autor y su equipo, tomando como base un cuestionario disponible en la literatura.  Se realizó estudio estadístico descriptivo y analítico mediante el software SPSS 15.0. Resultados: Se reclutaron 99 tutores con una edad media de 41 años, con formación universitaria 52%, profesional 27%, secundaria 17% y primaria 4%. Más del 70% de la muestra calificó positivamente el grado de información proporcionada en relación al procedimiento, su objetivo, su riesgo-beneficio y el tiempo de dedicación y de decisión. Un 50% de los tutores calificó negativamente la información proporcionada en cuanto al tratamiento alternativo, posibilidad de negar y revocar el CI.  La consistencia interna del cuestionario fue muy buena, con un valor de la alfa de Cronbach de 0.88. No se encontró correlación entre el grado de percepción y diversas variables demográficas o clínicas. Conclusiones: El grado de información percibida por los tutores es en general muy bueno. Las informaciones en relación a los procedimientos alternativos, la posibilidad de rechazo y revocación del CI fueron los puntos mejorables.
¿Hubo modernización de las fuerzas armadas españolas entre 1891 y 1935? Un análisis desde el punto de vista del gasto
Authors: Martos Gómez Jose Juan , Ortiz-Villajos José Maria
Published: March 2022

Este artículo pretende averiguar si las fuerzas armadas españolas se modernizaron entre 1891 y 1935. Para ello, se analiza el gasto de los ministerios militares (Guerra y Marina) desagregado entre gasto en material y gasto en personal. Se considera que un aumento del peso relativo del gasto en material es indicio de modernización. Según esto, las fuerzas armadas se modernizaron a lo largo del período estudiado, aunque la Armada lo hizo con mayor intensidad que el Ejército. Dicho avance coincidió con la reducción de la plantilla de oficiales y estuvo propiciado por los planes de reconstrucción de la Armada y la inversión en nuevo armamento para el Ejército, en buena medida impulsada por la guerra de Marruecos.
This paper tries to find out whether the Spanish armed forces modernized between 1891 and 1935. To that end, the expenditure of the military Ministries (Army and Navy), disaggregated into material and personnel expenditure, is analyzed. We consider that an increase in the relative weight of material expenditures is a sign of modernization. According with this, during the period of the study the Spanish armed forced experienced an advance in modernization, more intense in the Army than in the Navy. This advance was propitiated by the reconstruction plans of the Navy and the investment in new armament by the Army, considerably spurred by the war in Morocco.
Breadwinners in Spanish cities (1914-1930)
Authors: Borderías Mondejar Cristina , Muñoz-Abeledo Luisa , Cussó  Segura Xavier
Published: March 2022

Historic constructions of family budgets have been scarce in Spain. In fact, the first national Family Budget Survey was carried out in 1958. In this article, we present new evidence of different occupational groups’ incomes in Spanish provincial capitals (1914-1930). We also calculate the minimum cost of covering basic needs (food, housing, and other expenses) of urban working families. The main objective of the article is to estimate the capacity of men’s wages to sustain the family economy, as well as women’s contributions to the same. The main data sources are the Boletín del Instituto de Reformas Sociales 1904-1924 (Bulletin of the Institute of Social Reforms), the Anuario Estadístico de España 1914-30 (Spanish Statistical Yearbook), and the National Population Censuses (1910-1930), the food and nutrient totals prepared by García Barbancho (1960a and 1960b), and estimates of energy and nutrient requirements prepared by WHO/FAO and other specialists and institutions.
Challenges in the creation of the multilingual corpus-based lexicographic resource CombiDigiLex
Authors: Fernández Méndez Manuel , Mas Álvarez Inmaculada , Meliss Meike
Published: March 2022

The paper presents the methodological and technological challenges in the creation of the multilingual, corpus-based lexicographic resource CombiDigiLex (https://combidigilex.wixsite.com/deutsch), with three main aims. First, the application-oriented research context and grounds for the development of the multilingual lexico-grammatical information system CombiDigiLex, which is intended to provide information for the languages German, Spanish and Portuguese, for its use in the L2 production and translation process, are presented. Furthermore, the most relevant features of the mentioned resource in its current version (v.1.0.6) are presented. Finally, the methodological and technical difficulties of data gathering as well as lexicographic data displaying, that not only had to be overcome during the official project period, but which even at the time of writing this paper are still partly open fronts, are outlined.
écri+, un dispositif en ligne d’évaluation, de formation et de certification des compétences écrites en français
Authors: De Luca Gabriella , De Vogue Sarah , Lefebvre Julie , Sitri Frederique
Published: March 2022

Dans cet article, nous présentons les différents aspects d’un dispositif de remédiation de l’écrit en ligne pour les étudiants, élaboré dans le cadre d’un projet regroupant quinze universités françaises (projet écri+ (https://ecriplus.fr/), dont l’une des instigatrices est Sarah De Vogüé, qui en coordonne l’une des actions). Prenant comme exemple le traitement du discours rapporté et de la citation, activité emblématique de l’écrit universitaire, nous montrerons comment interagissent, dans la conception des tests et des activités, 1) le choix d’un modèle opératoire, 2) la constitution et l’analyse de corpus d’apprenants et de corpus d’experts, et 3) les contraintes liées au support numériques
Els sons del català: un recurs web per a l'aprenentatge i la recerca en l'àmbit de la fonètica i la fonologia catalanes
Authors: Pujol Xevi
Published: March 2022

En aquest article ressenyem el recurs web d'Els sons del català (http://www.ub.edu/sonscatala/ca), un projecte iniciat l'any 2006 pels professors del Departament de Filologia Catalana de la Universitat de Barcelona Josefina Carrera, Clàudia Pons i Joan Solà amb la intenció de crear una eina telemàtica per a l'aprenentatge i la recerca en l'àmbit de la fonètica i la fonologia catalanes. Es tracta d'un recurs polivalent que aplega continguts textuals i multimèdia molt diversos, de consulta fàcil, i molt significatius per a l'aprenentatge en el camp de la fonètica i la fonologia catalanes. El web es manifesta, doncs, molt útil com a recurs per a l'aprenentatge autònom tant per part d'estudiants de graus o de matèries en què es tracta la fonètica i la fonologia del català com per part d'aprenents de català que tenen aquesta llengua com a L2 o com a LE. Alguns aspectes del web el fan apte, també, com a suport per a la recerca. El web presenta una estructura coherent i senzilla que permet mostrar la informació de manera ordenada. Entre les diverses seccions del web descrites en aquest article destaquen la secció en què es mostra un inventari complet dels sons de cinc dels principals dialectes del català, organitzada en dues interfícies principals, la secció del glossari i la secció dels exercicis autocorrectius. Una enquesta resposta per part d'usuaris universitaris del web mostra que l'alumnat en fa una valoració global clarament favorable.
INFOLING: difusión de información global sobre lingüística hispánica
Authors: Subirats Rüggeberg Carlos
Published: March 2022

En este artículo se analizan las características y el desarrollo de Infoling (https://infoling.org/), una red online de difusión global de información sobre lingüística hispánica, que inició sus actividades informativas en 1996 y ha continuado su labor de forma ininterrumpida durante más de 25 años. Exponemos el proceso que nos ha llevado a determinar su estructura tanto funcional como organizativa, así como los contenidos que acoge, entre los que ocupa un lugar relevante la investigación sobre segundas lenguas (L2). Asimismo, analizamos los términos “lengua española” y “lingüística hispánica” para poder redefinirlos al margen de conceptualizaciones ideológicas. Finalmente, examinamos la creación y el desarrollo de los nuevos canales informativos de Infoling, que han permitido la difusión de reseñas y artículos de historiografía lingüística. En cuanto al futuro inmediato, nos planteamos la utilización de las plataformas audiovisuales y los metaversos para ponerlas al servicio de la difusión de información científica.
Modified fishnet structure with a wide negative refractive index band and a high figure of merit at microwave frequencies
Authors: Askari M. , Touhidi Nia Z. , Hosseini M. V.
Published: March 2022

Since realization of negative refractive index (NRI) metamaterials in 2001, which is about 20 years after its introduction as a pure academic concept in 1968, there has been much curiosity and enthusiasm for this field of study. Despite numerous potential applications, different loss mechanisms inherent to such materials have severely restricted their widespread usage. Based on this, NRI metamaterials with low losses are extensively studied in the literature. In this paper, we present a design to realize NRI at microwave frequencies which, to some degree, overcomes the limitations imposed by high intrinsic losses pertinent to such category of materials via bestowing a figure of merit (FOM) as high as 139.3. The layout includes two opposing parts, each containing a square slab in the middle of two crossing wires. The theoretical discussions unveiling the physics behind the NRI behavior, as well as effects of geometrical parameters, temperature, and the use of different metals on the FOM, are extensively discussed.
Yaws recurrence in children at continued risk of infection
Authors: Beiras Camila G. , Marks Michael , Quintó Llorenç , Gavilán Sergi , Kolmau Reman , Ubals Maria , Vall-Mayans Marti , Mitjà Oriol
Published: March 2022

Background

In yaws-endemic areas, children with Treponema pallidum subsp. pertenue infection may suffer recurrent episodes due to either reinfection or relapse. However, the possibility of infection with other cutaneous ulcer causative agents and difficulties in interpreting standard laboratory results challenges the estimation of yaws recurrence rates.

Methods

We estimated the rates of yaws recurrences in the Lihir Island (Papua New Guinea) using two approaches: passive surveillance based on a retrospective screening of electronic medical records of cutaneous ulcers diagnosed using serological testing between 2005 and 2016, and active surveillance conducted during a cross-sectional prevalence study which included PCR analyses of ulcers of all suspected cases of yaws. The risk of recurrent infection was assessed based on data from the passive surveillance analysis and using two Cox regression models (crude and multivariate), stratified by year of index episode. Data gathered from the active surveillance was used to characterize the recurrences and no hypothesis testing was performed.

Results

The electronic medical records included 6,125 patients (7,889 ulcer episodes) with documented serological results of cutaneous ulcers of which1,486 were diagnosed with yaws. Overall, 1,246/6,125 patients (20.3%) presented more than once with a cutaneous ulcer, and 103/1,486 (6.7%) patients had multiple episodes of yaws. The risk of yaws recurrence significantly increased with age and was higher in patients with ≥3 recurrent episodes. In the active surveillance, we identified 50 individuals with recurrent cutaneous ulcer that had PCR results available for both the index and recurrent episode. Of 12 individuals with T. pallidum in the index ulcer, 8 (66%) had T. pallidum in subsequent assessments, relapse related to macrolide-resistance was identified in two of these cases.

Conclusions

Our results confirm the need for active follow-up of yaws patients after treatment, particularly children and individuals with a history of recurrence.
Identification of a coproporphyrinogen-III oxidase gene and its correlation with nacre color in Hyriopsis cumingii
Authors: Chen Xiajun , He Jixiang , Zhang Mengying , Bai Zhiyi , Li Jiale
Published: March 2022

Pearl color is an important factor influencing pearl value, and is affected by the nacre color of the shell in Hyriopsis cumingii. Coproporphyrinogen-III oxidase (CPOX) is a key enzyme in porphyrin synthesis, and porphyrins are involved in color formation in different organisms, including in the nacre color of mussels. In this study, a CPOX gene (HcCPOX) was identified from H. cumingii, and its amino acid sequence was found to contain a coprogen-oxidase domain. HcCPOX mRNA was expressed widely in the tissues of white and purple mussels, and the highest expression was found in the gill, followed by the fringe mantle. The expression of HcCPOX in all tissues of purple mussels (except in the middle mantle) was higher than that of white mussels. Strong hybridization signals for HcCPOX were observed in the dorsal epithelial cells of the outer fold of the mantle. The activity of CPOX in the gill, fringe mantle, and foot of purple mussels was significantly higher than that in white mussels. Moreover, the expression of HcCPOX and CPOX activity were decreased in RNA interference experiments. The findings indicate that HcCPOX might contributes to nacre color formation in H. cumingii by being involved in porphyrin synthesis.
COVID-19 and screen-based sedentary behaviour: Systematic review of digital screen time and metabolic syndrome in adolescents
Authors: Musa Sarah , Elyamani Rowaida , Dergaa Ismail
Published: March 2022

Aim

The COVID-19 pandemic has prompted governments around the globe to implement various restriction policies, including lockdown, social distancing, and school closures. Subsequently, there has been a surge in sedentary behaviour particularly screen time (ST) together with a significant decline in physical activity that was more marked amongst children and adolescents. Excessive screen exposure in adolescents has been correlated with cardio-metabolic risk factors including obesity, hypertension, high cholesterol, and glucose intolerance that may have adverse morbidity and mortality implications in adulthood. Thus, the current study aimed to synthesize the literature on the relationship between ST of various types and the risk of metabolic syndrome (MetS) in adolescents in the context of the COVID-19 pandemic.

Methods

In August 2021, a systematic search of the literature was undertaken using electronic databases: PubMed, PsycINFO, and the Cochran library. Studies were considered if they met the following key eligibility criteria: (i) Measure of ST as an exposure (TV, computer, videogames, internet, smartphone, tablet), using quantified duration/frequency either self-reported or observed; (ii) Measure of MetS as an outcome with standard definition and/or criteria required to establish MetS diagnosis. The Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies was used to assess the risk of bias.

Results

A total of ten studies met the inclusion criteria, and the majority were cross sectional studies. Most studies met fair bias scoring. Overall, the review revealed considerable evidence that suggests a significant negative association between ST and components of MetS among adolescents with dose-response association.

Conclusion

During the pandemic, screen usage may become more prevalent through periods of school closures, lockdowns, social isolation, and online learning classes. Public health policies and health promotion strategies targeting parents are needed to raise awareness of the adverse health effects associated with screen-based sedentary behaviour as a precursor of NCDs. Parent or home focused interventions might be effective in limiting adolescents’ screen exposure, alternatively substituted with an appropriate level of physical activity.

PROSPERO registration number

PROSPERO 2021 CRD42021272436.
Risk factors for Encapsulating Peritoneal Sclerosis in patients undergoing peritoneal dialysis: A meta-analysis
Authors: Li Dashan , Li Yuanyuan , Zeng Hanxu , Wu Yonggui
Published: March 2022

Purpose

Encapsulating Peritoneal Sclerosis (EPS) is the most serious complication of long-term peritoneal dialysis (PD), which considerably reduces the patient’s quality of life, leading to patients discontinuing PD. Considering these negative effects, it is necessary to systematically review and determine the risk factors of EPS.

Methods

The PubMed, Embase, Web of Science, Cochrane Library, and China Biology Medicine (CBM) were searched from their inception to January 1st, 2022, and the bibliographies from the citations of relevant articles were manually searched. The ROBINS-I (Risk of Bias in Non-randomized studies of Interventions) tool was used to evaluate the risk of bias of included studies.

Results

Ten studies involving 12595 participants were included in this meta-analysis. The results revealed that a younger age at PD onset (MD = -7.70, 95% CI, -11.53~-3.86), a higher transporter (MD = 0.13, 95% CI, 0.09~0.18), a longer PD duration (SMD = 1.15, 95% CI, 0.68~1.61), a longer peritonitis duration (MD = 12.66, 95% CI, 3.85~21.47), and history of glomerulonephritis (OR = 1.42, 95% CI, 1.02~1.97) were significant risk factors for EPS. However, sex, use of icodextrin, the number of peritonitis episodes, and history of multicystic kidney disease did not affect the risk of EPS.

Conclusions

This review provides a scientific basis for further understanding the etiology of PD-related EPS and improving prevention strategies. More high-quality studies are necessary to validate this paper’s findings.
From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer
Authors: Martins Mathias , Boggiatto Paola M. , Buckley Alexandra , Cassmann Eric D. , Falkenberg Shollie , Caserta Leonardo C. , Fernandes Maureen H. V. , Kanipe Carly , Lager Kelly , Palmer Mitchell V. , Diel Diego G.
Published: March 2022

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19) in humans, has a broad host range, and is able to infect domestic and wild animal species. Notably, white-tailed deer (WTD, Odocoileus virginianus), the most widely distributed cervid species in the Americas, were shown to be highly susceptible to SARS-CoV-2 in challenge studies and reported natural infection/exposure rates approaching 30–40% in free-ranging WTD in the U.S. Thus, understanding the infection and transmission dynamics of SARS-CoV-2 in WTD is critical to prevent future zoonotic transmission to humans, at the human-WTD interface during hunting or venison farming, and for implementation of effective disease control measures. Here, we demonstrated that following intranasal inoculation with SARS-CoV-2 B.1 lineage, WTD fawns (~8-month-old) shed infectious virus up to day 5 post-inoculation (pi), with high viral loads shed in nasal and oral secretions. This resulted in efficient deer-to-deer transmission on day 3 pi. Consistent a with lack of infectious SARS-CoV-2 shedding after day 5 pi, no transmission was observed to contact animals added on days 6 and 9 pi. We have also investigated the tropism and sites of SARS-CoV-2 replication in adult WTD (3–4 years of age). Infectious virus was detected up to day 6 pi in nasal secretions, and from various respiratory-, lymphoid-, and central nervous system tissues, indicating broad tissue tropism and multiple sites of virus replication. The study provides important insights on the infection and transmission dynamics of SARS-CoV-2 in WTD, a wild animal species that is highly susceptible to infection and with the potential to become a reservoir for the virus in the field.
A qualitative study of an online Makaton choir for individuals with learning difficulties
Authors: Quigley Hannah , MacDonald Raymond
Published: March 2022

This qualitative study investigates the experiences of individuals with learning difficulties who participate in Makaton choirs. Semi-structured interviews were conducted with five choir members and a leader. Thematic analysis revealed that participants reported increased opportunities for social connection with others. Participants also reported that performing sign language to song supported the acquisition of Makaton, leading to improvements in communication. Through providing a space for the development of communication and increased social interaction, Makaton choirs present opportunities for creating social relationships and for accessing and participating in new social contexts. In addition, an improved ability to use and understand Makaton sign language allows participants to access the lyrical content of songs, leading to an enhanced understanding of the experience of emotion through music. It is argued that participation in such a group may promote health and well-being by providing participants with a number of psychological and social benefits. Directions for future research are also presented.
Hidden voices: Towards a trauma-informed framework of community music practice
Authors: Birch Catherine
Published: March 2022

As the field of community music scholarship continues to evolve, opening up a dialogue around music making with trauma survivors and implementation of trauma-informed practice is both timely and critical. Whilst there has been an acknowledgement of the presence of trauma connected to specific contexts, community music literature has not yet begun to respond to the potential prevalence of trauma within any community music setting. As a field in which music projects will often be operating with groups of vulnerable people, trauma-informed practice is beginning to be acknowledged, but without a broad base of research to support training and implementation. As a community musician working with known trauma survivors, it is my assertion that the question of whether pedagogic frameworks should be developed in order to promote safe and appropriate practices needs to be addressed, especially where traumatic experience can remain hidden, but still be profoundly impactful. This article explores the origins of trauma-informed practice as well as providing an example framework from the York St John University Prison Partnership Project. A literature review of community music scholarship explores the potential benefits of music making for those who have experienced trauma and emerging themes are examined through the lens of trauma-informed practice. This article also suggests that trauma-informed practice could be integrated more widely within community music in order to: (1) acknowledge that in any group or context, statistically, a number of participants are likely to have experienced trauma; (2) acknowledge that because trauma is often hidden, having an understanding of manifestations of trauma responses will better equip practitioners; (3) understand that trauma-informed practice enables practitioners to work reflexively and responsively within their groups, thereby building solid foundations on which to develop safe and secure environments in which music making can flourish.
Photonic graphene under strain with position-dependent gain and loss
Authors: Castillo-Celeita Miguel , Contreras-Astorga Alonso , Fernández C. David J.
Published: March 2022

We work with photonic graphene lattices under strain with gain and loss, modeled by the Dirac equation with an imaginary mass term. To construct such Hamiltonians and their solutions, we use the free-particle Dirac equation and then a matrix approach of supersymmetric quantum mechanics to generate a new Hamiltonian with a magnetic vector potential and an imaginary position-dependent mass term. Then, we use a gauge transformation that maps our solutions to the final system, photonic graphene under strain with a position-dependent gain/loss term. We give explicit expressions for the guided modes.
From quartic anharmonic oscillator to double well potential
Authors: Turbiner Alexander V. , Del Valle Juan Carlos
Published: March 2022

Quantum quartic single-well anharmonic oscillator Vao(x) = x2 + g2x4 and double-well anharmonic oscillator Vdw(x) = x2(1−gx)2 are essentially one-parametric, they depend on a combination (g2ℏ). Hence, these problems are reduced to study the potentials Vao = u2 + u4 and Vdw = u2(1 − u)2, respectively. It is shown that by taking uniformly-accurate approximation for anharmonic oscillator eigenfunction Ψao(u), obtained recently, see JPA 54 (2021) 295204 [1] and arXiv 2102.04623 [2], and then forming the function Ψdw(u) = Ψao(u)±Ψao(u−1) allows to get the highly accurate approximation for both the eigenfunctions of the double-well potential and its eigenvalues.
Time-dependent mass oscillators: constants of motion and semiclasical states
Authors: Zelaya Kevin
Published: March 2022

This work reports the construction of constants of motion for a family of time-dependent mass oscillators, achieved by implementing the formalism of form-preserving point transformations. The latter allows obtaining a spectral problem for each constant of motion, one of which leads to a non-orthogonal set of eigensolutions that are, in turn, coherent states. That is, eigensolutions whose wavepacket follows a classical trajectory and saturate, in this case, the Schrödinger-Robertson uncertainty relationship. Results obtained in this form are relatively general, and some particular examples are considered to illustrate the results further. Notably, a regularized Caldirola-Kanai mass term is introduced in an attempt to amend some of the unusual features found in the conventionalCaldirola-Kanai case.
ANALISIS PENINGKATAN FASILITAS KEAMANAN PEMUSTAKA DI PERPUSTAKAAN FAKULTAS KEDOKTERAN, KESEHATAN MASYARAKAT DAN KEPERAWATAN UNIVERSITAS GADJAH MADA DI ERA NEW NORMAL
Authors: Romadhona Alfi Gladis , Tafrikhuddin Tafrikhuddin
Published: March 2022

This study aims to find out how to improve the security facilities of the FK-KMK UGM Library in preparing the infrastructure for user security facilities in the new normal era and to find out how the security facilities used in the FK-KMK UGM library in ensuring the safety of users in the new normal era. This research is a type of qualitative descriptive research. Data collection techniques are observation, interviews and documentation. The data analysis technique used in this research is data reduction, data presentation and conclusion drawing. Based on this study, it was concluded that the level of user safety in the FK-KMK UGM library in the new normal era can be seen from the adaptation efforts made by the library, from online and offline services and the availability of security facilities in the form of handwashing facilities, temperature measurement sites and the availability of hand sanitisers at each room.
CHALLENGES AND OPPORTUNITIES OF ONLINE LIBRARY SERVICES IN THE NEW NORMAL: THE WESTERN MINDANAO STATE UNIVERSITY EXPERIENCE
Authors: Asid Benhur Abdulaup
Published: March 2022

As higher education institutions strictly follow health protocols due to the COVID-19 pandemic, moving of classes including the closing of libraries is a way of helping the government to mitigate the spread of Coronavirus. To that effect, libraries have also responded to the challenging needs in the educational system. In the Western Mindanao State University library where online services are offered, where the purpose of this study attempted to look into the challenges and opportunities faced by its stakeholders and the extent of satisfaction. The quantitative-qualitative research design employing a descriptive survey method was used. In the selection of respondents, systematic random sampling was also employed, and the five (5) point Likert-type questionnaire checklist was utilized. While a purposive sampling was also employed to library personnel. A total of 384 respondents coming from the students, faculty administrative personnel/staff, and library personnel were utilized. Based on the findings, OLC or the Online Library Cart facilitated by a social media platform was a big help to educators and learners in the academic community. The challenges and opportunities have also brought in the delivery of online services’ operation. The low internet connectivity and lack of personnel competency in the online delivery, among others were considered as challenges. In attaining quality library service, increase in the acquisition of e-resources, upgrading of personnel’s skills as well as strengthening the culture of partnership and collaboration are major factors to create an avenue to improve library services, the online delivery, in particular. The overall mean of 4.74 revealed a high level of satisfaction result from the three groups of respondents, implying that WMSU library online services are very much effective and functioning excellently. It is, therefore, concluded that online services offered by the WMSU Library should be sustained not only to respond to the COVID-19 pandemic but also to support the challenging needs of blended learning education in Western Mindanao.
Synthesis of Dansyl Cyclen and Preliminary Study of Its Fluorescent Properties
Authors: Kadidae La Ode , Ruslin Ruslin , Azis Thamrin , Aba La , Kadir Laode Abdul
Published: March 2022

The synthesis of a dansyl cyclen-based compound as a potential chemical sensor has been carried out. The initial study of its fluorescent properties has also been conducted. This study aims to synthesize a cyclen-based compound comprising three identical pendant arms and another different arm carrying a dansyl fluorophore. Producing these heterogenous pendant arms, a-three pendant arm cyclen 9 was reacted with dansyl aziridine 10. The synthesis products were characterized using 1H NMR, 13C NMR, IR, and elemental analysis. In addition, a Fluorescent Spectrophotometer has been used to assess the fluorescent intensity changes of the synthetic ligand in a range of pH 2–13 and when it was titrated with some metal ions. Based on the results of characterization with 13C NMR for compound 2 and additional characterization with IR and elemental analysis for its hydrochloric form 11, it is wisely said that the proposed compound has been successfully synthesized, giving 66% yield as viscous brown oil 2. Moreover, the fluorescent property showed that the higher the pH employed, the higher the fluorescent intensity observed. Meanwhile, the addition of some cationic metals revealed that cadmium (II) gave the highest increase in the fluorescent intensities among other cationic metals.