bluuebunny/crossref_metadata_2025 huggingface dataset:
Location-Aware Caching for Semantic-Based Image Queries in Mobile AD HOC Networks
Authors: Yang Bo , Mareboyana Manohar
Published: April 2012

Mobile image information retrieval, i.e., the processing of mobile image queries, has attracted research attention due to the recent technological advances in mobile and ubiquitous computing, network infrastructures, and multimedia streaming. The previous research focuses on data delivery, while few works have reported on content-based mobile information retrieval. Therefore, it is important to devise effective means to describe the semantics as well as content distribution of mobile data. Caching is an attractive solution that helps reveal semantic relationships among mobile data sources. However, traditional caching techniques rely on exact match of fixed values and are not efficient in dealing with imprecisely described image data. To address these issues, the authors propose a location-aware caching model which reflects the distribution of images based on the analysis of earlier queries. Through extensive simulations, the authors show that the proposed model can perform search with less cost for voluminous data.
An Evaluation of Color Sorting for Image Browsing
Authors: Schoeffmann Klaus , Ahlström David
Published: April 2012

Many image browsing tools employ a scrollable grid-like arrangement of thumbnails of images for enabling users to browse through image collections. The thumbnails in these arrangements are typically sorted by some kind of metadata, e.g., by filename or creation date. However, users looking for a specific image in mind prefer search by visual similarity rather than search based on simple metadata. In difference to previous work, which rarely present results from user studies, the authors provide empirical evidence that color sorting is an effective approach for that purpose. With a user survey, the authors identify which of six alternative color sorting algorithms produces the most intuitive result. The authors use the best algorithm, a simple HSV-based sorting method, and compare users’ visual search performance in a color sorted storyboard against performance in an unsorted storyboard. The results show that color sorting can improve user interaction, both in terms of subjective impressions and visual search times.
Knowledge Strategy
Authors: Kasten Joseph E.
Published: April 2012

Knowledge strategy is defined as the set of guidelines and philosophies that guide an organization’s knowledge-based activities, such as knowledge gathering, development, storage, and utilization. Much of the early literature describing knowledge strategy suggests that its role in the organization is to drive, and be driven by, organizational structure and the human resources and technology strategies. This paper derives a model that places the firm’s knowledge strategy as a mitigating factor between the decisions made by management and the manner in which they are communicated to the rest of the organization. The present research is an update to a previously published paper and extends the research that first generated the metaphor of the KS as a lens.
The Pricing Strategy Guideline Framework for SaaS Vendors
Authors: Spruit Marco , Abdat Nizar
Published: April 2012

Software as a Service has become a dominant IT news topic over the last few years. Especially in these current recession times, adopting SaaS solutions is increasingly becoming the more favourable alternative for customers rather than investing on brand new on-premise software or outsourcing. This fact has inevitably stimulated the birth of numerous SaaS vendors. Unfortunately, many small-to-medium vendors have emerged only to disappear again from the market. A lack of maturity in their pricing strategy often becomes part of the reason. This paper presents the ‘Pricing Strategy Guideline Framework(PSGF)’ that assists SaaS vendors with a guideline to ensure that all the fundamental pricing elements are included in their pricing strategy. The PSGF describes five different layers that need to be taken to price software: value creation, price structure, price and value communication, price policy, and price level. The PSGF can be of particularly great use for the start-up vendors that tend to have less experience in pricing their SaaS solutions. There have been no SaaS pricing frameworks available in the SaaS research area, such as the PSGF developed in this research. The PSGF is evaluated in a case study at a Dutch SaaS vendor in the Finance sector.
Case Studies and Organisational Sustainability Modelling Presented by Cloud Computing Business Framework
Authors: Chang Victor , De Roure David , Wills Gary , Walters Robert John
Published: April 2012

In this paper, Cloud Computing Business Framework (CCBF) is proposed to help organisations achieve good Cloud design, deployment, migration, and services. Although organisations adopt Cloud Computing for Web Services, technical and business challenges emerge, including the measurement of Cloud business performance. Organisational Sustainability Modelling (OSM) is a way to measure Cloud business performance quantitatively and accurately. It combines statistical computation and 3D Visualisation to present the Return on Investment arising from the adoption of Cloud Computing by organisations. 3D visualisation simplifies the review process and is a method for Return of Investment (ROI) valuation. Two detailed case studies with SAP and Vodafone are presented, where OSM has analysed the business performance and explained how CCBF offers insights, which are helpful for WS and Grid businesses. Comparisons and discussions between CCBF and other approaches related to WS are presented, where lessons learned are useful for Web Services, Cloud and Grid communities.
SIRPα/CD172a and FHOD1 Are Unique Markers of Littoral Cells, a Recently Evolved Major Cell Population of Red Pulp of Human Spleen
Authors: Ogembo Javier Gordon , Milner Danny A. , Mansfield Keith G. , Rodig Scott J. , Murphy George F. , Kutok Jeffery L. , Pinkus Geraldine S. , Fingeroth Joyce D.
Published: April 2012

Asplenic individuals are compromised not only in their ability to destroy infectious agents, but are at increased risk for death from autoimmune disease, certain tumors, and ischemic heart disease. Enhanced mortality is attributed to lack of phagocytes sequestered in spleen that efficiently engulf and destroy appropriate targets, although related cells are found elsewhere. To determine whether a unique population regulates RBC-pathogen clearance and filtration of altered self, we reviewed the anatomic literature and analyzed in situ by immunohistochemistry and immunofluorescence the expression patterns of a little-characterized cell that dominates the splenic red pulp of humans and closely related primates: the venous sinus-lining or littoral cell (LC). High expression of the formin homology domain protein 1 outlines the LC population. Although LCs are endothelial-like in distribution, they express several macrophage-directed proteins, the RBC Duffy Ag receptor for chemokines and T cell coreceptor CD8α/α, yet they lack lineage-associated markers CD34 and CD45. Strikingly, SIRPα (CD172a) expression in human spleen concentrates on LCs, consistent with recent demonstration of a key role in RBC turnover and elimination versus release of infected or altered self. Our results indicate human LCs (SIRPα+, formin homology domain protein 1+, CD8α/α+, CD34−, CD45−) comprise a highly plastic barrier cell population that emerged late in primate evolution coordinate with CD8 expression. Unique to Hominidae, LCs may be the ultimate determinant of which cells recirculate after passage through human spleen.
L’atteinte de l’objet chez l’enfant né prématuré
Authors: O’Sullivan Laura P. , Goubet Nathalie , Berthier Neil E.
Published: April 2012

Résumé Des enfants sains nés à terme et des enfants prématurés ont fait l’objet d’une étude longitudinale basée sur une tâche d’atteinte d’objet. Les bébés à terme ont été étudiés à 6, 8 et 10 mois, et les bébés prématurés à 6, 8 et 10 mois d’âge corrigé. Dans la première partie de la tâche, les bébés devaient atteindre un objet nouveau présenté seul. Dans la seconde phase, deux objets étaient présentés dont l’un déjà présenté précédemment et donc devenu familier. Un système d’analyse du mouvement a été utilisé pour mesurer les caractéristiques cinématiques des mouvements vers les cibles. Les réponses visuelles à la nouveauté ont été globalement comparables dans les deux groupes d’enfants, ainsi que le nombre de pics de vitesse et la durée du mouvement et de la préhension. Mais les autres mesures différencient nettement les deux groupes. Par exemple, la vitesse du mouvement diminue avec l’âge chez les bébés nés à terme, en accord avec les données de la littérature, tandis qu’elle augmente avec l’âge chez les bébés nés prématurés. Ces résultats suggèrent des trajectoires développementales différentes chez les bébés nés à terme et les bébés prématurés.
Methotrexate induced lung injury in a patient with primary CNS lymphoma: A case report
Authors: Chhabra Puneet , Dutt law Arjun , Suri Dr vikas , Malhotra Dr pankaj , Varma Dr subhash
Published: April 2012

Methotrexate is an antimetabolite commonly used in clinical practice for a variety of indications ranging from rheumatoid arthritis and other connective tissue disorders to high dose regimens in many malignancies. This folate antagonist has got a spectrum of toxicities among which gastrointestinal effects predominate . Lung injury is a well described but rare event and has been reported most often in patients who have been on long term oral therapy for rheumatic disorders. Acute lung injury in a patient receiving a high dose regimen for haematological malignancies has not been reported previously. We present one such case of methotrexate related acute lung injury in a patient of primary CNS lymphoma receiving high dose methotrexate.
Mini placas versus pines en fracturas diafisiarias de metacarpo en el Hospital Escuela de Tegucigalpa Honduras del 1 de enero del 2009 al 30 de junio de 2010.
Authors: Editorial Comité , Bermúdez Guillermo , Idiáquez Diego
Published: April 2012

Palabras clave: metacarpiano; fractura; miniplaca; pinesDOI: http://dx.doi.org/10.5377/rmpm.v13i3.624 Revista de los Postgrados de Medicina UNAH Vol. 13 N° 3 Agosto-Octubre 2010
Morbilidad relacionada al legrado uterino instrumental en la enfermedad trofoblastica gestacional
Authors: Editorial Comité , Valladares Néstor Fabián , Moreno Fátima
Published: April 2012

Palebras claves: legrado uterino instrumental; enfermedad trofoblastica gestacionalDOI: http://dx.doi.org/10.5377/rmpm.v13i3.626  Revista de los Postgrados de Medicina UNAH Vol. 13 N° 3 Agosto-Octubre 2010
Nutricion enteral temprana versus tardia en el paciente pediatrico criticamente enfermo
Authors: Editorial Comité , Castillo Karen , Sanchez Carlos , Munguia Lirio , Rivera Maria Felix
Published: April 2012

Palebras clave: Desnutricion; nutricion enteral; caloriasDOI: http://dx.doi.org/10.5377/rmpm.v13i3.628 Revista de los Postgrados de Medicina UNAH Vol. 13 N° 3 Agosto-Octubre 2010
Prevalencia de Síndrome metabólico en pacientes con psoriasis, mayores de 40 años.
Authors: Editorial Comité , Mendoza Johanna Melissa , López Elmer , Romera María Guadalupe
Published: April 2012

Palabras clave: Síndrome metabólíco; psoriasisDOI: http://dx.doi.org/10.5377/rmpm.v13i3.629 Revista de los Postgrados de Medicina UNAH Vol. 13 N° 3 Agosto-Octubre 2010
Clinical Requests for Molecular Tests: The 3-Step Evidence Check
Authors: Carter Alexis B
Published: April 2012

Laboratory tests performed by molecular methods are increasing in volume and complexity at an unprecedented rate. Molecular tests have a broad set of applications, and most recently have been advocated as the mechanism by which providers can further tailor treatments to the individual patient. As the momentum behind molecular testing continues to increase, pathology practices may find themselves unprepared for the new wave of molecular medicine. This special article has been developed in an effort to provide pathologists who have limited molecular training with a simple and quick algorithm for determining whether a requested molecular test is appropriate for a patient. Additional recommendations for a more intensive and proactive review and management of molecular requests also are included. The principles discussed can easily be applied to requests for any test, including those not using molecular methods, which would be sent to an outside reference laboratory. This special article was developed from a Webinar for the College of American Pathologists targeting education for pathologists about the transformation of pathology practice in the new molecular and digital age.
Asymmetrical Hip Bone Density in Multiple Sclerosis
Authors: Larson Rebecca D. , White Lesley J.
Published: April 2012

As multiple sclerosis (MS) may affect one leg more than the other, we predicted that bone mineral density (BMD) would be lower in the limb self-identified as more affected. Therefore, the purpose of this study was to determine whether ambulatory individuals with MS displaying moderate-to-severe lower-extremity paresis exhibit asymmetrical femoral neck BMD. Dual-energy x-ray absorptiometry was used to assess proximal femoral neck BMD. Lower BMD was observed in the proximal femoral neck of the more paretic limb (P = .001) in a group (N = 23) of ambulatory individuals with relapsing-remitting MS (RRMS). Our preliminary findings suggest that bilateral hip screening may be important in the early detection of compromised bone health in ambulatory individuals with RRMS. Further research is warranted to fully characterize the factors and mechanisms associated with bone loss and identify effective strategies for optimizing bone health in people with MS.
Impact of a 10-Week Individualized Exercise Program on Physical Function and Fatigue of People with Multiple Sclerosis
Authors: Vore Mary Ellen , Elgelid Staffan , Bolger Shannon , Parsons Caroline , Quashnoc Rachel , Raymor Johanna
Published: April 2012

Research has found that people with multiple sclerosis (MS) who engage in exercise programs experience improvements in physical and psychological health, resulting in enhanced quality of life. These studies have involved structured exercise protocols, but few have examined the effects of an individualized exercise program allowing for peer socialization. The purpose of this study was to investigate the effects of a 10-week individualized exercise program offering opportunities to socialize with peers on fatigue and physical functioning in people with MS. Thirteen individuals with a physician diagnosis of MS were enrolled in a 10-week exercise program at Nazareth College in Rochester, New York. Eleven participants (9 female, 2 male; mean ± SD age, 55.0 ± 7.06 years) completed the study. The following qualitative and quantitative measures were used for evaluation before and after the exercise program: Multiple Sclerosis Quality of Life–54 (MSQOL-54), Activities-specific Balance Confidence (ABC) scale, Modified Fatigue Impact Scale (MFIS), Timed Up and Go (TUG) test, Timed 10-Meter Walk (T10MW) test, functional reach test, and single-leg stance (SLS) test. Statistically significant differences were found for the TUG (P = .005), T10MW (P = .014), and MFIS physical functioning subscore (P = .039). The results showed significant increases in gait speed and mobility as well as decreased impact of fatigue on physical functioning after the 10-week exercise program.
Informal Caregivers Assisting People with Multiple Sclerosis
Authors: Buchanan Robert J. , Huang Chunfeng
Published: April 2012

The objective of this study was to identify characteristics of informal caregivers, caregiving, and people with multiple sclerosis (MS) receiving this assistance that are associated with the strength of the care-giver/care recipient relationship. Data were collected in a national survey of informal caregivers and analyzed using an ordered logistic regression model to identify factors associated with caregiver perceptions of the strength of the relationship with the person with MS. The overall health of the person with MS was significantly associated with caregiver perceptions that providing assistance strengthened the caregiver/care recipient relationship, with poor health having a negative impact on the relationship. A spousal relationship between the caregiver and the person with MS was associated with significantly lower perceptions of a strengthened relationship. Conversely, caregiver perceptions that MS symptoms interfered with the independence of the person with MS in daily life were associated with caregiver perceptions of a strengthened relationship. Longer duration of caregiving and more hours per week spent providing assistance also were associated with a stronger relationship. In contrast, we found a significant negative association between caregiver perceptions that assisting the person with MS was burdensome and the strength of the relationship. Similarly, higher levels of education among caregivers tended to have a significantly negative impact on the caregiver/care recipient relationship. Our findings highlight the importance of addressing the needs and concerns of spousal caregivers. Health professionals who treat informal caregivers, as well as those treating people with MS, should be sensitive to the impact caregiving has on caregivers, especially spouses providing assistance.
Home-Based Computer-Assisted Cognitive Training
Authors: Stuifbergen Alexa , Becker Heather , Morgan Stephanie , Morrison Janet , Perez Frank
Published: April 2012

Initial evidence suggests that computer-assisted cognitive rehabilitation may improve cognitive performance among people with multiple sclerosis (MS). Most studies of computer-assisted cognitive training have incorporated an individualized in-office/clinic approach for training. The purpose of this study was to explore the feasibility of home-based computer-assisted training and systematically examine the perceptions of people with MS regarding home use of the program. Qualitative data (written and verbal) obtained as part of a larger randomized clinical trial of a cognitive rehabilitation intervention were analyzed. The computer training component of the intervention included prescribed tracks and exercises on the Internet-based Neuropsychonline program. The majority of the participants used the program the recommended number of times per week and for the minimum number of minutes over the 8-week intervention. Although participants had notable negative perceptions and complaints about the program during the training experience, most of them acknowledged during training that use of the program helped them recognize cognitive limitations, create and practice strategies to increase cognitive function, and improve the quality of their daily life. Data from focus groups 3 months after the training included similar criticisms regarding lack of feedback and difficulties with the program as well as acknowledgment of the positive effects and a desire for continued access to the program. The findings suggest that while home training is feasible, careful preparation for use of the program is required.
Summary of Eye Examinations of 284 Patients with Multiple Sclerosis
Authors: Roodhooft Jan M.
Published: April 2012

The aim of this article is to report the findings of ocular examinations in a group of patients diagnosed with multiple sclerosis who were referred to the eye department of the Nationaal Multiple Sclerosis Centrum of Melsbroek, Belgium, from 2007 to 2010. Patients were evaluated by a single examiner, who noted visual acuity for distance, the state of the optic disks, oculomotor balance, and the presence of nystagmus, uveitis, trigeminal neuralgia, and facial palsy. The sample consisted of 284 adults born between 1920 and 1989: 111 males and 173 females. There were 51 patients with a corrected visual acuity in the better-seeing eye of less than 6/20. The optic nerve head was found to be normal in 245 eyes. Nystagmus was noted in 104 patients. Diplopia at distance was found to be present in 20 males, of whom 12 also had nystagmus, and in 31 females, of whom 13 also had nystagmus. Oscillopsia was present in 6 males and 11 females. In summary, most of the patients evaluated had sufficient visual function to allow performance of activities of daily living without help. A small number of patients had visual failure due to dysfunction of the visual sensory pathway and/or disturbances of oculomotor balance, often of a supranuclear origin, resulting in considerable disability.
Contemporary Architecture of Iran
Authors: Diba Darab
Published: April 2012

Notions of identity, culture, tradition and history are key to understanding the contemporary architecture of Iran. Darab Diba explains how the establishment of the Islamic Republic of Iran in 1979 broke with an approach that for almost two centuries had directly equated modernity with Western influence. A revival of interest in Iran's own ‘Iran‐ness’ initially manifested itself in a retrospective interest in historic styles, but has more recently shifted into a sophisticated appreciation of the essence of the country's heritage.
Rapid Degradation of Azo Dye by Fe‐Based Metallic Glass Powder
Authors: Wang Jun‐Qiang , Liu Yan‐Hui , Chen Ming‐Wei , Xie Guo‐Qiang , Louzguine‐Luzgin Dmitri V. , Inoue Akihisa , Perepezko John H.
Published: April 2012

The outstanding efficiency of Fe‐based metallic glass powders in degrading organic water contaminants is reported. While the glassy alloy contains 24% chemically inactive metalloid elements, the powders are capable to completely decompose the C32H20N6Na4O14S4 azo dye in aqueous solution in short time, about 200 times faster than the conventional Fe powders. The metastable thermodynamic nature and the particle surface topography are the major factors controlling the chemical performance of the metallic glass. Our findings may open a new opportunity for functional applications of metallic glasses.
Mesoporous Silica Nanoparticle‐based H2O2 Responsive Controlled‐Release System Used for Alzheimer's Disease Treatment
Authors: Geng Jie , Li Meng , Wu Li , Chen Cuie , Qu Xiaogang
Published: April 2012

Metal ions play important roles in amyloid aggregation and neurotoxicity. Metal‐ion chelation therapy has been used in clinical trials for Alzheimer's disease (AD) treatment. However, clinical trial studies have shown that long‐term use of metal chelator can cause adverse side effect, subacute myelo‐optic neuropathy. Nanoparticle engineering processes have become promising approaches for efficiently drugs delivery. A series of modified mesoporous silica nanoparticles (MSNs) using redox, pH, competitive binding, light, and enzyme as actuators have been demonstrated. Recently, significant advances in sensing oxidative stress have been made by taking advantage of specific chemistry between cellular oxidants such as H2O2. Here we report a biocompatible delivery platform by using H2O2 responsive controlled‐release system to realize target delivery of AD therapeutic metal chelator. The advantage of this novel strategy is that metal chelator can only be released by the increased levels of H2O2, thus, it would not interfere with the healthy metal homeostasis and can overcome strong side effect of metal chelator after long‐term use. By taking advantage of the good biocompatibility, cellular uptake properties, and efficient intracellular release of metal chelators, the delivery system is promising for future in vivo controlled‐release biomedical applications.
Scanning Probe Study on the Piezotronic Effect in ZnO Nanomaterials and Nanodevices
Authors: Zhang Yue , Yan Xiaoqin , Yang Ya , Huang Yunhua , Liao Qingliang , Qi Junjie
Published: April 2012

ZnO nanomaterials with their unique semiconducting and piezoelectric coupled properties have become promising materials for applications in piezotronic devices including nanogenerators, piezoelectric field effect transistors, and diodes. This article will mainly introduce the research progress on piezotronic properties of ZnO nanomaterials investigated by scanning probe microscopy (SPM) and ZnO‐based prototype piezotronic nanodevices built in virtue of SPM, including piezoelectric field effect transistors, piezoelectric diodes, and strain sensors. Additionally, nanodamage and nanofailure of ZnO materials and their relevant piezotronic nanodevices will be critically discussed in their safe service in future nanoelectromechanical system (NEMS) engineering.
An Unusal Case of Facile Non‐Degenerate PC Bond Making and Breaking
Authors: Nesterov Vitaly , Özbolat‐Schön Aysel , Schnakenburg Gregor , Shi Lili , Cangönül Asli , van Gastel Maurice , Neese Frank , Streubel Rainer
Published: April 2012

Oxidation of Li/X phosphinidenoid complex 2, obtained via selective deprotonation from the P‐H precursor 1, with [Ph3C]BF4 led to the formation of two P‐F substituted diorganophosphane complexes 6,7; the latter tautomer 7 formed via H‐shift from 6. In contrast, oxidation of 2 with [(p‐Tol)3C]BF4 led to three major and one minor intermediates at low temperature, which we tentatively assign to two pairs of P‐C atropisomers 10a,a′ and 10c,c′ and which differ by the relative orientations of their CH(SiMe3)2 and W(CO)5 groups. Conversion of all isomers led finally to complex 11 having a ligand with a long PC bond to the central trityl* carbon atom, firmly established by single‐crystal X‐ray analysis. DFT calculations at the B3LYP/def2‐TZVPP//BP86/def2‐TZVP level of theory on real molecular entities revealed the structures of the in situ formed combined singlet diradicals (4+5 and 5+9) and the nature of intermediates on the way to the final product, complex 11. Remarkable is that all isomers of 11 possess relative energies in the narrow energy regime of about 20 kcal mol−1. A preliminary study revealed that complex 11 undergoes selective PC bond cleavage at 75 °C in toluene solution.
Reactivity toward oxygen radicals and antioxidant action of thiol compounds
Authors: Takashima Mizuki , Shichiri Mototada , Hagihara Yoshihisa , Yoshida Yasukazu , Niki Etsuo
Published: April 2012

Thiol compounds exert diverse functions in the defense network against oxidative stress in vivo. Above all, the role of glutathione in the enzymatic removal of hydrogen peroxide and lipid hydroperoxides has been well established. The scavenging of reactive free radicals is one of the many functions. In this study, the reactivities of several thiol compounds toward oxygen‐ and nitrogen‐centered radicals were measured from their reaction with galvinoxyl and 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radicals and also from their sparing effects on the decay of fluorescein, pyrogallol red, and BODIPY induced by peroxyl radicals. Furthermore, the antioxidant capacity against lipid peroxidation was assessed in the oxidation of methyl linoleate induced by free radicals in micelle systems. Cysteine, homocysteine, and glutathione exhibited considerable reactivity toward galvinoxyl, DPPH, and peroxyl radicals in this order but methionine did not. Bovine serum albumin (BSA) was less reactive toward these radicals than cysteine on molar base. Cysteine, homocysteine, and glutathione suppressed the oxidation of methyl linoleate in micelle systems, but methionine did not. The reactivity toward free radicals and antioxidant capacity of these thiol compounds were less than that of ascorbic acid, but higher than that of uric acid.
Lipid rafts generate digital‐like signal transduction in cell plasma membranes
Authors: Suzuki Kenichi G. N.
Published: April 2012

Lipid rafts are meso‐scale (5–200 nm) cell membrane domains where signaling molecules assemble and function. However, due to their dynamic nature, it has been difficult to unravel the mechanism of signal transduction in lipid rafts. Recent advanced imaging techniques have revealed that signaling molecules are frequently, but transiently, recruited to rafts with the aid of protein‐protein, protein‐lipid, and/or lipid‐lipid interactions. Individual signaling molecules within the raft are activated only for a short period of time. Immobilization of signaling molecules by cytoskeletal actin filaments and scaffold proteins may facilitate more efficient signal transmission from rafts. In this review, current opinions of how the transient nature of molecular interactions in rafts generates digital‐like signal transduction in cell membranes, and the benefits this phenomenon provides, are discussed.
ChemInform Abstract: The System Ta—V—Si: Crystal Structure and Phase Equilibria.
Authors: Khan A. U. , Broz P. , Niu H. Y. , Bursik J. , Grytsiv A. , Chen X.‐Q. , Giester G. , Rogl P.
Published: April 2012

Phase relations in the title system are evaluated for the isothermal sections at 1500 and 1200 °C.
ChemInform Abstract: Two New Noncentrosymmetric (NCS) Polar Oxides: Syntheses, Characterization, and Structure—Property Relationships in BaMTe2O7 (M: Mg2+ or Zn2+).
Authors: Yeon Jeongho , Kim Sang‐Hwan , Nguyen Sau Doan , Lee Hana , Halasyamani P. Shiv
Published: April 2012

The new title compounds are prepared by solid state reaction of stoichiometric mixtures of BaCO3, MgCO3 or ZnO, TeO2, and H2TeO4·2H2O (alumina crucible, 650 °C, 3 d).
ChemInform Abstract: Two‐Stage Optimization of a Supramolecular Catalyst for Catalytic Asymmetric Hydroboration.
Authors: Moteki Shin A. , Toyama Kazuya , Liu Zeyu , Ma Jing , Holmes Andrea E. , Takacs James M.
Published: April 2012

A series of self‐assembled ligand Zn‐catalysts [cf.
ChemInform Abstract: [3 + 2] Cycloaddition of Seleno‐ and Thioaldehydes with Cyclic Azomethine Imines.
Authors: Maeda Hajime , Takamizawa Yusuke , Segi Masahito
Published: April 2012

The reaction of seleno‐ and thioaldehydes generated in situ from (I) with cyclic azomethine imines (II) in toluene gives [3 + 2] cycloadducts (III) in high yields.
ChemInform Abstract: Amination of Benzoxazoles and 1,3,4‐Oxadiazoles Using 2,2,6,6‐Tetramethylpiperidine‐N‐oxoammonium Tetrafluoroborate as an Organic Oxidant.
Authors: Wertz Sebastian , Kodama Shintaro , Studer Armido
Published: April 2012

Direct amination of non‐activated benzoxazoles and 1,3,4‐oxadiazoles is achieved by treatment with tetramethylpiperidine‐N‐oxoammonium tetrafluoroborate as an oxidant in the presence of catalytic amounts of triflic acid or scandium triflate.
ChemInform Abstract: Nitrile Alkylations Through Sulfinyl—Metal Exchange.
Authors: Nath Dinesh , Fleming Fraser F.
Published: April 2012

Sulfinylnitriles, e.g. (I), (XII), (XV) or (XVII), smoothly undergo sulfinyl—metal exchange with Grignard reagents, organolithium or lithium zincate reagents to generate the corresponding α‐metallated nitriles, which are trapped with various electrophiles.
ChemInform Abstract: An Efficient Protocol for the Amidation of Carboxylic Acids Promoted by Trimethyl Phosphite and Iodine.
Authors: Luo Qun‐Li , Lv Lina , Li Yu , Tan Jian‐Ping , Nan Wenhui , Hui Qun
Published: April 2012

A mild and efficient method for the direct N‐acylation of amines with carboxylic acids is presented to afford a wide variety of aromatic and aliphatic amides.
ChemInform Abstract: Palladium‐Catalyzed Decarboxylation of Allenyl 3‐Oxoalkanoates: An Efficient Synthesis of 3,4‐Allenyl Ketones.
Authors: Wan Baoqiang , Jia Guochen , Ma Shengming
Published: April 2012

The versatile synthons are readily available under conditions A) in either tBuOH or THF.
ChemInform Abstract: Enantioselective Intermolecular Carbon—Carbon Bond Formation of Glyoxylate Imines with Allylstannanes Catalyzed by tropos BIPHEP—Gold(I) Complexes with Au—Au Interactions.
Authors: Kojima Masafumi , Mikami Koichi
Published: April 2012

The present study reveals the advantage of tropos BIPHEP—gold(I) complexes with intramolecular Au—Au interactions compared to the structurally similar atropos BINAP—gold complexes without the Au—Au interaction.
ChemInform Abstract: Asymmetric Synthesis of Trisubstituted Allenes: Copper‐Catalyzed Alkylation and Arylation of Propargylic Phosphates.
Authors: Uehling Mycah R. , Marionni Samuel T. , Lalic Gojko
Published: April 2012

In contrast to previous reports, the reaction of a propargylic phosphate with a bulky substituent at the γ‐position [cf.(VII)] succeeds with good yields and high enantioselectivity.
ChemInform Abstract: Palladium‐Catalyzed Direct ortho‐Alkynylation of Aromatic Carboxylic Acid Derivatives.
Authors: Ano Yusuke , Tobisu Mamoru , Chatani Naoto
Published: April 2012

The aminoquinoline directing group promotes the ortho‐alkynylation without the need of any silver salts.
ChemInform Abstract: Hydrosilylation of Ketones Catalyzed with Mg—Al—O‐tBu Hydrotalcite.
Authors: Chen Yaoyun , Bai Ying , Peng Jiajian , Li Jiayun , Lai Guoqiao
Published: April 2012

The efficacy of tBu‐O‐AlMg‐hydrotalcite as heterogeneous catalyst for the hydrosylilation of ketones is studied.
ChemInform Abstract: Enantio‐ and Diastereoselective Addition of Cyclohexyl Meldrum′s Acid to β‐ and α,β‐Disubstituted Nitroalkenes via N‐Sulfinyl Urea Catalysis.
Authors: Kimmel Kyle L. , Weaver Jimmie D. , Ellman Jonathan A.
Published: April 2012

A practical method for the construction of biologically important chiral γ‐amino acids is based on the title reaction in the presence of a sulfinyl urea catalyst.
ChemInform Abstract: An Efficient and Practical Synthesis of Aryl and Hetaryl α‐Keto Esters.
Authors: Raghunadh Akula , Meruva Suresh Babu , Kumar Nuka Anil , Kumar Gudla Santosh , Rao L. Vaikunta , Kumar U. K. Syam
Published: April 2012

as important substructures of biologically active substances
ChemInform Abstract: A Reactivity Switch in the Gold‐Catalyzed Coupling of Allyl Sulfides with Propargylic Carboxylates.
Authors: Davies Paul W. , Albrecht Sebastien J.‐C.
Published: April 2012

Depending on the non‐migrating substituent on the sulfur and the aromatic group at the propargylic position of the alkyne, the reaction follows different reaction pathways.
ChemInform Abstract: Phosphine‐Free Conversion of Alcohols into Alkyl Thiocyanates Using Trichloroisocyanuric Acid/NH4SCN.
Authors: Azadi Roya , Mokhtari Babak , Makaremi Mohamad‐Ali
Published: April 2012

The combination is successfully employed for the conversion of alcohols into thiocyanates and isothiocyanates, respectively.
ChemInform Abstract: Retropinacol Rearrangement in the Synthesis of 3,3,4‐Trimethyl‐2‐azaspiro[4.5]deca‐1,6,9‐trien‐8‐one Derivatives.
Authors: Shklyaev Yu. V. , Stryapunina O. G. , Maiorova O. A.
Published: April 2012

With the object to obtaining biologically active substances, the three‐component reaction of anisole (I), pivalaldehyde (II) and nitriles (III) is performed.
ChemInform Abstract: Efficient Synthesis of Bis(heterocyclyl)methanes.
Authors: Singh Kamaljit , Sharma Shivali , Sharma Amit
Published: April 2012

An efficient synthesis of a number of meso‐elaborated bis(heterocyclyl)methanes such as (IV) and (VII), which are otherwise difficult to obtain through a direct aldehyde condensation route, is developed.
ChemInform Abstract: Effective Synthesis of 1,5‐Disubstituted 2,1‐Benzisothiazol‐3(1H)‐ones.
Authors: Kharul Rajendra K. , Prajapati Pinkal N. , Thorave Amol A. , Shah Hardik A. , Dhar Arghya , Joshi Darshan A. , Jain Mukul R. , Patel Pankaj R. , Pancholi S. S.
Published: April 2012

An improved procedure is used for the preparation of 1,5‐disubstituted benzoisothiazoles, e.g. (VI).
ChemInform Abstract: Synthesis of New Sulfinyl Derivatives of 4,5‐Diphenyl‐4H‐1,2,4‐triazoles.
Authors: Rodygin K. S. , Rubtsova S. A. , Kuchin A. V.
Published: April 2012

Sulfides (I) are oxidized to the corresponding sulfoxides (II) using Kagan′s reagent and cumene hydroperoxide as an oxidant.
ChemInform Abstract: Synthesis of Polyhydroxylated Xanthones via Acyl Radical Cyclizations.
Authors: Kraus George A. , Liu Feng
Published: April 2012

Treatment of 2‐formylphenoxyquinones (III) with NBS in the presence of AIBN generates unstable xanthones via acyl radical cyclization.
ChemInform Abstract: Nickel‐Catalyzed Dehydrogenative [4 + 2] Cycloaddition of 1,3‐Dienes with Nitriles.
Authors: Ohashi Masato , Takeda Ippei , Ikawa Masashi , Ogoshi Sensuke
Published: April 2012

The title reaction allows an efficient and regioselective access to a wide range of pyridines.
ChemInform Abstract: New Ylidene Derivatives of Pyrrolo[2,1‐a]isoquinoline‐2,3‐dione in the Synthesis of Dispiropyrrolidines.
Authors: Shvets A. A. , Mikhailovskii A. G. , Zimakov D. V. , Kurbatov S. V. , Surikova O. V.
Published: April 2012

Condensation of dione (I) with rhodanine (II) affords the thiazolidin‐5‐ylidene (III) in moderate yield.
ChemInform Abstract: Construction of a Six‐Membered Fused N‐Heterocyclic Ring via a New 3‐Component Reaction: Synthesis of (Pyrazolo)pyrimidines/pyridines.
Authors: Kumar P. Mahesh , Kumar K. Siva , Mohakhud Pradeep Kumar , Mukkanti K. , Kapavarapu R. , Parsa Kishore V. L. , Pal Manojit
Published: April 2012

A one‐pot TfOH‐catalyzed cascade affords title series (IV) and (VI).
ChemInform Abstract: One‐Pot Synthesis of 4‐Aminoquinazolines by Hexamethyldisilazane‐Mediated Reaction of Quinazolin‐4(3H)‐ones with Amines.
Authors: Shen Zhen‐Lu , He Xiao‐Fei , Hong Yi‐Ming , Hu Xin‐Quan , Mo Wei‐Min , Hu Bao‐Xian , Sun Nan
Published: April 2012

An efficient method for the synthesis of 4‐aminoquinazolines (II) is developed.
ChemInform Abstract: Convenient Preparation of Bicyclic Guanidines.
Authors: Usachev Sergei , Gridnev Alexei
Published: April 2012

A new synthesis of 1,5,7‐triazabicyclo[4.4.0]dec‐5‐ene (TBD) is given.
ChemInform Abstract: N‐Alkylation of Unsymmetrical 1,6‐Dihydro‐1,2,4,5‐tetrazine under Alkali Condition.
Authors: Xu Feng , Yang Zhen‐Zhen , Zhang Shi‐Jie , Hu Wei‐Xiao
Published: April 2012

The products (III) decompose gradually at room temperature and should be stored at ‐20 °C.
ChemInform Abstract: Polyethylene Glycol Promoted Dialkyl, Aryl/Heteroaryl Phosphonates
Authors: Naidu K. Reddi Mohan , Dadapeer E. , Reddy C. Bhupendra , Rao A. Janardhan , Reddy C. Suresh , Raju C. Naga
Published: April 2012

An efficient, ecofriendly synthesis of novel phosphonates (III) (12 examples) in polyethylene glycol, which serves as reaction medium and catalyst, is achieved.
ChemInform Abstract: One‐Pot, Three‐Component Synthesis of 5‐(Alkylimino)‐2‐ (diethoxyphosphoryl)‐2,5‐dihydrofuran‐3,4‐dicarboxylates.
Authors: Azizian Javad , Ramazani Ali , Haji Mohammad , Azizkhani Vahid
Published: April 2012

A facile one‐pot, multicomponent method for the synthesis of 2‐phosphono‐substituted furans (V) is described and a reasonable reaction mechanism is proposed.
ChemInform Abstract: New Luminescent Dyes from the Series of 1,3,7‐Substituted Dibenzothiophene‐5,5‐diones.
Authors: Ol'khovik V. K. , Petushok V. G. , Kalechits G. V. , Baranovskii A. V.
Published: April 2012

The new linear polyconjugated compounds (I) and (II) show strong luminescence in solutions as well as in the solid state and exhibit electroluminescent properties.
ChemInform Abstract: Synthetic Approach to 4a‐Methyltetrahydrofluorene‐Type Diterpenoids via an Aromatic Oxidation of Phenol Derivatives.
Authors: Chen Wuhong , Kobayashi Koichi , Takahashi Kazunori , Honda Toshio
Published: April 2012

An aromatic oxidation with a hypervalent iodine reagent is used as a strategy for the preparation of the title compounds.
ChemInform Abstract: Adsorption of Chromium(VI) by Metal Hydroxide Sludge from the Metal Finishing
Authors: Perrin Loic , Laforest Valerie , De Roy Marie , Forano Claude , Bourgois Jacques
Published: April 2012

Review: 24 refs.
ChemInform Abstract: A Review of Electrode Materials for Electrochemical Supercapacitors
Authors: Wang Guoping , Zhang Lei , Zhang Jiujun
Published: April 2012

Review: 475 refs.
ChemInform Abstract: Cucurbituril Chemistry: A Tale of Supramolecular Success
Authors: Masson Eric , Ling Xiaoxi , Joseph Roymon , Kyeremeh‐Mensah Lawrence , Lu Xiaoyong
Published: April 2012

Review: 413 refs.
ChemInform Abstract: Greener Reactions under Solvent‐Free Conditions
Authors: Marvaniya Hiren M. , Modi Kaumil N. , Sen Dhrubo Jyoti
Published: April 2012

Review: 37 refs.
ChemInform Abstract: Grafted Polysaccharides: Smart Materials of the Future, Their Synthesis and Applications
Authors: Sen Gautam , Sharon Ashoke , Pal Sagar
Published: April 2012

Review: 98 refs.
ChemInform Abstract: The Pyrrolo[2,1‐α]isoquinoline Alkaloids
Authors: Paessler Ulrike , Knoelker Hans‐Joachim
Published: April 2012

Review: 127 refs.
ChemInform Abstract: Phenyltrifluorosilane in Organoelemental and Organic Synthesis
Authors: Voronkov M. G. , Trofimova O. M. , Grebneva E. A. , Chernov N. F. , Abzaeva K. A.
Published: April 2012

Review: 126 refs.
ChemInform Abstract: Triazines, Tetrazines, and Fused Ring Polyaza Systems
Authors: Prokhorov Anton M. , Kozhevnikov Dmitry N.
Published: April 2012

Review: 93 refs.
ChemInform Abstract: Five‐Membered Ring Systems with O and N Atoms
Authors: Cicchi Stefano , Cordero Franca M. , Giomi Donatella
Published: April 2012

Review: 121 refs.
ChemInform Abstract: Five‐Membered Ring Systems with N and S (Se) Atoms
Authors: Wu Yong‐Jin , Yang Bingwei V.
Published: April 2012

Review: 65 refs.
ChemInform Abstract: Physical Chemistry of Supramolecular Polymer Networks
Authors: Seiffert Sebastian , Sprakel Joris
Published: April 2012

Review: 263 refs.
Visible‐Light Photooxidation of Water to Oxygen at Hybrid TiO2–Polyheptazine Photoanodes with Photodeposited Co‐Pi (CoOx) Cocatalyst
Authors: Bledowski Michal , Wang Lidong , Ramakrishnan Ayyappan , Bétard Angélique , Khavryuchenko Oleksiy V. , Beranek Radim
Published: April 2012

A cobalt oxide‐based oxygen‐evolving cocatalyst (Co‐Pi) is photodeposited by visible‐light irradiation onto nanocrystalline TiO2–polyheptazine (TiO2–PH) hybrid photoelectrodes in a phosphate buffer. The Co‐Pi cocatalyst couples effectively to photoholes generated in the surface polyheptazine layer of the TiO2–PH photoanode, as evidenced by complete photooxidation of water to oxygen under visible‐light (λ>420 nm) irradiation at moderate bias potentials. In addition, the presence of the cocatalyst also reduces significantly the recombination of photogenerated charges, particularly at low bias potentials, which is ascribed to better photooxidation kinetics resulting in lower accumulation of holes. This suggests that further improvements of photoconversion efficiency can be achieved if more effective catalytic sites for water oxidation are introduced to the surface structure of the hybrid photoanodes.
Interdependent binary choices under social influence: Phase diagram for homogeneous unbiased populations
Authors: Fernández del Río Ana , Korutcheva Elka , de la Rubia Javier
Published: April 2012

Coupled Ising models are studied in a discrete choice theory framework, where they can be understood to represent interdependent choice making processes for homogeneous populations under social influence. Two different coupling schemes are considered: the nonlocal or group interdependence model is used to study two interrelated groups making the same binary choice and the local or individual interdependence model represents a single group, where agents make two binary choices that depend on each other. For both models, phase diagrams and their implications in socioeconomic contexts are described and compared in the absence of private deterministic utilities (zero opinion fields). © 2012 Wiley Periodicals, Inc. Complexity, 2012
Stem cell maintenance in the adult mammalian hippocampus: A matter of signal integration?
Authors: Schwarz Tobias J. , Ebert Birgit , Lie D. Chichung
Published: April 2012

The continuous generation of new neurons from stem cells in the hippocampal dentate gyrus is considered an important contributor to hippocampal plasticity. A prerequisite for the life‐long generation of new dentate granule neurons is the maintenance of the neural stem cell pool. A number of essential molecular regulators and signals for hippocampal neural stem cell maintenance have been identified, but how these pathways interact to prevent precocious differentiation or exhaustion of the stem cell pool is currently unknown. Here, we summarize the current knowledge on the molecular regulation of the hippocampal stem cell pool and discuss the possibility that signal integration through Notch signaling controls stem cell maintenance in the adult hippocampus. © 2012 Wiley Periodicals, Inc. Develop Neurobiol 72: 1006–1015, 2012
Aliphatic Dicarboxylate Ligands Assemble Weakly Coupled Molecular Pairs of [MnIII]2 Units
Authors: Gómez Verónica , Corbella Montserrat , Fernández Gema , Roubeau Olivier , Teat Simon J. , Maestro Miguel A.
Published: April 2012

Seven new tetranuclear MnIII compounds have been obtained by assembling two dinuclear units, [{Mn(L)(NN)}2(μ‐O)]4+, with aliphatic dicarboxylate ligands COO(CH2)nCOO2–: succinato (n = 2, C42–), glutarato (n = 3, C52–) and adipato (n = 4, C62–), and NN = 2,2′‐bipyridine (bpy) or 1,10‐phenanthroline (phen). The general formula for these compounds is [{Mn(L)(NN)}4(μ‐Cm)2(μ‐O)2]X4 [X = ClO4, NN = bpy and Cm = C4 (1), C5 (2) and C6 (3); X = ClO4, NN = phen and Cm = C4 (4), C5 (5) and C6 (6); X = NO3, NN = bpy and Cm = C5 (7)]. Compounds 1, 2 and 4 were characterized by X‐ray diffraction, which confirmed the assembly of two dinuclear entities. The magnetic properties of the seven compounds were studied and the results indicate that the main interaction takes place within the dinuclear units. Compound 4 shows a dominant ferromagnetic coupling with J = 4.0 cm–1, while the rest of compounds display antiferromagnetic couplings with J values of –2.8 (1), –1.9 (2), –3.3 (3), –0.3 (5), –0.4 (6) and –9.3 cm–1 (7), which are all in agreement with magneto‐structural correlations. In the case of compound 4, a weak but significant antiferromagnetic coupling of the S = 4 [MnIII]2 subunits with an interaction constant of –0.9 cm–1 was observed.
When Cyclodextrins Meet Click Chemistry
Authors: Faugeras Pierre‐Antoine , Boëns Benjamin , Elchinger Pierre‐Henri , Brouillette François , Montplaisir Daniel , Zerrouki Rachida , Lucas Romain
Published: April 2012

Cyclodextrins are important building blocks in organic chemistry. This review deals with the role of click chemistry in this family of cyclic oligosaccharides, focusing on the different areas of chemistry, including chromatography, biological applications, the elaboration of superstructures, and metal detection, that benefit from this reaction. In this paper, attention is given to organic modifications by using functionalizations such as azidation and propargylation and to click chemistry grafting onto the two faces of cyclodextrins. Research papers where cyclodextrins are not directly involved in a click chemistry reaction are not considered.
Tuning Wavefunction Mixing in Push–Pull Molecules: From Neutral to Zwitterionic Compounds
Authors: Capobianco Amedeo , Esposito Antonio , Caruso Tonino , Borbone Fabio , Carella Antonio , Centore Roberto , Peluso Andrea
Published: April 2012

A new push–pull molecule, containing an (alkylamino)thiophene as electron donor and 1,3‐bis(dicyanomethylidene)‐2‐indenylindene as electron acceptor, has been synthesized and characterized in the solid state by X‐ray crystallography, in solution by UV/Vis and NMR spectroscopy and by theoretical calculations. The quinoidal zwitterionic form of this compound was underscored both in the solid state and in moderately polar solvents. Experimental and theoretical analyses were also performed on two similar push–pull molecules, selectively chosen to vary basic chemical features such as the resonance energy of the aromatic group and the steric hindrance of the attractor. Comparative analysis of the three compounds has shown that steric hindrance, resonance energy and the polarity of the environment play a significant role in stabilizing one limiting resonance form over the other. By varying these chemical variables, fine tuning of the electronic ground state of a push–pull molecule, from the neutral aromatic form to the charge‐separated zwitterion, passing through a form in which the two limiting forms contribute almost equally (the cyanine limit), can be achieved.