bluuebunny/crossref_metadata_2025 huggingface dataset:
VALIDITAS SKALA UKUR NYERI VISUAL ANALOG AND NUMERIK RANTING SCALES (VANRS) TERHADAP PENILAIAN NYERI
Authors: Andreyani Linda , Bhakti Wida Kuswida
Published: July 2023

Visual Analog and Numerik Ranting Scale (VANRS) adalah Skala nyeri yang dikebangkan oleh peneliti dengan mengabungkan Visual Analog Scale (VAS)  dan Numerik Ranting Scale (NRS). Kebaruan dalam penelitian ini karena meneliti tentang validitas skala ukur nyeri Visual Analog and Numerik Ranting Scale (VANRS) terhadap penilaian nyeri. Penelitian ini bertujuan untuk mempermudah saat melakukan anamnesa pada pasien sehingga data subjektif dan objektif didapatkan untuk menentukan kasus yang terjadi apakah emergency atau tidak, dapat dipergunakan pada berbagai macam kasus atau diagnosis baik itu bayi atau pediatrik, anak, dewasa dan geriatri dalam keadaan sadar maupun yang mengalami penurunan kesadaran. Metode penelitian yaitu dengan menggunakan Stiker Emoticon Skala Nyeri yang diberi rentang nilai dengan warna dan angka kemudian stiker tersebut di tempelkan ke spuit 10 cc kemudian dilakukan uji coba secara langsung terhadap 45 partisipan dengan mengidentifikasi secara langsung respon nyeri partisipan dengan menggunakan alat yang di dikembangkan oleh peneliti yaitu VANRS kemudian dilakukan olah data dengan menggunakan SPSS 25 untuk validasi data. Penelitian ini telah mendapatkan persetujuan Komite Etik dan Hukum dengan Nomor : 400.7.4.2/0249/RSUD-B. Hasil penelitian menunjukkan adanya korelasi yang kuat antara VAS dan NRS nyeri dengan uji korelasi Spearmans (rho=0,937 P0,001). Kesimpulan bahwa tidak ada perbedaan yang signifikan antara tool nyeri dalam subkelompok yaitu antara VAS dan NRS sehingga tool nyeri yang dibuat bisa dipergunakan sebagai media untuk melakukan pengkajian.
KORELASI AKSES SANITASI DAN AKSES AIR MINUM DENGAN KEJADIAN STUNTING PADA BALITA DI WILAYAH KABUPATEN SERANG TAHUN 2022
Authors: Paramasatya Adhika , Wulandari Ririn Arminsih
Published: July 2023

Stunting adalah penggambaran status gizi kurang pada bayi sejak dalam kandungan hingga dilahirkan yang bersifat kronik pada masa pertumbuhan dan perkembangan. Namun, pada tahun 2022 prevalensi stunting di Kabupaten Serang mencapai 8.96% (11.534 balita menderita stunting). Kebaruan penelitian ini karena meneliti korelasi akses sanitasi dan akses air minum dengan kejadian stunting pada balita. Tujuan dari penelitian ini adalah untuk mengetahui korelasi akses sanitasi dan akses air minum dengan kejadian stunting pada balita di wilayah Kabupaten Serang tahun 2022. Desain studi pada penelitian ini adalah studi ekologi. Analisis korelasi dilakukan terhadap akses sanitasi dan akses air minum dengan angka kejadian stunting pada balita di 326 desa yang ada di Kabupaten Serang. Analisis data dilakukan secara univariat untuk mengetahui gambaran variabel independen dan dependen. Selanjutnya dilakukan analisis bivariat dengan menggunakan Uji Korelasi Spearman. Penelitian dilaksanakan selama bulan Desember 2022 – Februari 2023. Hasil penelitian berdasarkan hasil uji statistik Spearman didapatkan nilai P = 0,463 (P 0,05) sehingga tidak ada hubungan atau korelasi antara akses sanitasi dengan angka kejadian stunting pada balita di Kabupaten Serang. Sedangkan Hasil Hubungan akses air minum dengan kejadian stunting di Kabupaten Serang menunjukkan korelasi lemah dan memiliki arah negatif hal dapati dilihat dari nilai P = 0,038 (P 0.05) Kesimpulan Tidak ada hubungan atau korelasi antara akses sanitasi dengan angka kejadian stunting pada balita di Kabupaten Serang. Sedangkan hubungan akses air minum dengan kejadian stunting di Kabupaten Serang menunjukkan korelasi yang lemah dan memiliki arah negatif
CASE REPORT ON ABDOMINAL TUBERCULOSIS-A RARE PRESENTATION
Authors: J Bhavna R , Hidayath Hussain Mohammed , Afreen Hina , Tasneem Mansoora , Afreen Sumayya
Published: July 2023

Abdominal tuberculosis is a rare condition in developed nations and can be challenging to diagnose.it generally can occur
as a chronic condition often mimicking other diseases such as crohn's disease and can present itself with acute onset
,which can be life threatening.it can occur as a primary infection without evidence of pulmonary infection . Female genital tract is also a rare form
of extra pulmonary tuberculosis.it can present as number of abdominopelvic symptoms .we report a case of abdominal tuberculosis which is a rare
presentation in 16 year old female presented with abdominal pain.
ROLE OF RTPCR IN THE DIAGNOSIS OF DENGUE
Authors: Joshi Chetana , Arjunwadkar Vidya , Joshi Suvarna , Karyakarte Rajesh
Published: July 2023

Introduction: Dengue is commonly found in tropical and subtropical zones. The gold standard for diagnosing and
serotyping the virus is through virus isolation. However, a helpful biomarker for diagnosis is NS1, which is released by
infected cells 5 to 6 days after the onset of the disease. In settings with a high sample load, the Dengue NS1 ELISA test is a cost-effective and more
efcient option. NS1 antigen is considered a surrogate marker for viremia. Additionally, the Dengue RT-PCR test can detect viral RNA not only in
primary and secondary dengue infections but also in cases of infection with DENV-4 within 24-48 hours of the acute stage of the disease.
Therefore, the aim of this study was to evaluate the role of RT-PCR in patients with acute febrile illness caused by dengue. We analyzed Methods:
a total of 150 samples from patients with acute febrile illnesses. Specically, we included 50 samples from patients with NS1 ELISA-positive
dengue fever, 50 samples from patients suspected of having dengue fever but with NS1 ELISA-negative results, and an additional 50 samples
from patients with other types of acute febrile illnesses. We extracted viral RNA from whole blood samples collected from the 150 patients, and
then performed a dengue Real Time PCR analysis. Our study revealed that relying s Results: olely on NS1 ELISA testing may result in a missed
diagnosis of dengue fever in 30% of acute febrile cases. For accurate diagnosis of de Conclusion: ngue in the acute stage of febrile illness, we
recommend using a combination of NS1 ELISA and dengue RT-PCR, especially when NS1 ELISA results are negative.
“DETECTION OF VARIOUS VIRULENCE FACTORS OF CANDIDA SPECIES ISOLATED FROM DIFFERENT CLINICAL SPECIMENS”
Authors: Menka Menka , E. Chand Anita , Verma Dinesh
Published: July 2023

Background - C. albicans is generally considered as most pathogenic member of the genus and most common cause of different types of candidiasis. However, many recent studies from various parts of world have documented a shift frompervasive' C. albicans to 'cryptic' Non albicans Candida (NAC) species. NAC spp. are closely related to C. albicans and cause similar clinical manifestations but differ with respect to epidemiology, virulence factors and most importantly the pattern of susceptibility to antifungal drugs. Aim and objectives- Material To detect phospholipase, lipase, hemolysin activity of Candida species isolated from different clinical specimens. and methods- From April 2021 to March 2022 at Govt. Medical College, Kota. A total of 100 Candida species isolated from different clinical specimens further identied using standard mycological procedures. Phospholipase, lipase and hemolysin activities were detected by growth on egg yolk agar, tween 80 agar and SDA with blood media respectively. Out of 100 Ca Result- ndida isolates 38(38%) were C. albicans and 62(62%) were Non albicans Candida (NAC) including 42(42%) C. tropicalis, 10(10%) C. parapsilosis, 8(8%) C. glabrata, 2(2%) C. krusei. Phospholipase, lipase and hemolysin activities were detected 49(49%), 44(44%) and 68(68%) respectively. Conclusion- Detection of virulence factors might improve understanding of behaviour of Candida species and open doorways to management and prognosis of patients.
COMPARING THE EFFICACY OF FLIP CLASS OVER DIDACTIC LECTURE IN TEACHING ABSTRACT CONCEPTS OF ANATOMY FOR MEDICAL STUDENTS.
Authors: Anitha V. , Badusha M. , Harissh G.
Published: July 2023

Background: Flip classroom is a pedagogical approach in which instructions upgrade from the group learning space to
individual learning space and the resultant group space is transformed into a dynamic interactive learning environment
where the educator guides the students as they apply concepts. In this study we compared the effectiveness of ipped classroom with didactic
lectures in teaching abstract concepts of anatomy for undergraduate medical students A Comparative study was done Materials And Methods:
in Department of Anatomy, Government Villupuram Medical College for a period of 2 months among 100 undergraduate medical students.
Ethical committee approval was obtained. Transgender Attitude and Beliefs Scale (TABS) & validated MCQ questionnaire on knowledge (30
questions) were used. Responses for TABS was answered on a Likert scale with scores ranging from 1 to 7 (Wilcoxon rank-sum test used). MCQs
were assessed by scoring one point for one question (Unpaired t-test used). After the Results: session, the group which attended ipped classroom
had a statistically signicantly higher post session score compared to the lecture group. Flipped classrooms are better at conveying Conclusions:
complex concepts than conventional didactic lectures. Flip classroom provides a good opportunity for teachers to teach through video and clarify
the next day in person. It improves the students access to content, potential for family support and a good emphasis on the student.
LOOP ELECTROCAUTERY IN THE MANAGEMENT OF GIANT RHINOPHYMA – A CASE REPORT.
Authors: Sarkar Monideepa , Bhaumik Soumendu , Mahato Radheshyam , Das Saumik
Published: July 2023

A 56 years old male patient presented to our institution with a gradually progressive bulbous, multi-lobular, non-tender,rm, rubbery swelling of tip and dorsum of nose over last 20 years, extending to bilateral alae, with prominent skin pores, causing functional and cosmetic impairment. Condition was clinically diagnosed as rhinophyma and accorded 6 points under Rhinophyma Severity Scale. Under general anaesthesia, excision was done by shaving of the mass from underlying cartilage without damaging it, with the use of loop electro-cautery. Wound was allowed to granulate and heal by secondary intention, with no recurrence observed in follow-up. Histopathological examination conrmed rhinophyma
A PROSPECTIVE STUDY ON THE MANAGEMENT OF UPPER URETERIC CALCULI AT A TERTIARY CARE CENTRE
Authors: B Rajanna , T Shivakumar , B R Muralidhar , Sachin Sachin
Published: July 2023

Background: Various options are available for the management of ureteric colic, including conservative management, medical expulsion therapy, and surgical intervention. Primary management of ureteric stones is dependent on various factors, including patient presentation, clinical assessment, and stone characteristics. In the present study, we evaluated and managed all the upper ureteric calculi with respect to feasibility of various procedures, clearance of the stones and their complications. A cross- Methods: sectional study was conducted among 70 patients > 12 years of age with upper ureteric calculi attending Hassan institute of medical sciences, Hassan. All Procedure related complications & side effects during admission & follow-up were documented. 33 (42.9%) patients Results: underwent URSL(Pneumatic) and 33(42.9%) underwent Laser URSL. During guidewire insertion under uoroscopic guidance using cystoscope, the stones were dislodged and migrated in 7 patients and among them 5(6.5%) in ICL (Pneumatic with ureteroscopy) and 2(2.6%) in Laser ureteroscopy procedure. The migrated stone treated with PCNL/RIRS depending upon the size of stones. Stone fragments were migrated in 2 patients who underwent Pneumatic ICL lithotripsy and 1(1.3%) in patients who underwent Laser lithotripsy and it is conrmed byuoroscopy. In 4 (5.2%) of our patient's stones were impacted and large (>20mm) and guidewire could not be negotiated across the stone and hence Ureterolithotomy (Open /Lap) performed and other 2 (2.6%) of our patients did not accept invasive procedures and hence underwent ESWL and 5 (6.5%) were treated medically. In medical treatment, all the patients advised to take Tamsulosin 0.4 mg HS & NSAID'S for 4 weeks and advised to drink water >3.5 litre orally so as to achieve 2.5 litre of urine output. 2(2.6%) patients could not complete the course because of intermittent pain, so they advise URSL, remaining 2 patients completed the course but there was no clearance of the stone, NCCT KUB done and advised for denitive treatment. Stone clearance was higher in LAP/OPEN Conclusion: ureterolithotomy, Laser Lithotripsy. However, the difference in stone clearance rate between various procedures was not signicant. It can be stated that non-invasive procedures are as effective as open surgeries. However, selection of treatment should be based upon the factors such as size, location, Hounseeld units and others which can optimize the outcome for patients who have upper ureteral calculi.
RHEUMATOID ARTHRITIS ASSOCIATED NECROTISING SCLERITIS-A CASE SCENARIO
Authors: Macheria Preethi , Veluri Haritha , Singh Manmeet
Published: July 2023

We report a case of rheumatoid arthritis associated necrotising scleritis without inammation. The patient was successfully treated with scleral patch graft under immunosupressive agent cover, the patient is doing well with good scleral integrity with BCVA 6/6.
STUDY TO FIND OUT RENAL PARAMETER AND SERUM CALCIUM LEVEL IN PERINATAL ASPHYXIA
Authors: kumar Shashi , Pansari Vishnu
Published: July 2023

Background: Perinatal asphyxia is dened as lack of blood ow or gas exchange in the fetus at birth. As kidneys are very
sensitive to oxygen deprivation, renal insufciency may occur within 24 hours of a hypoxic ischaemic episode, which if
prolonged, may even lead to irreversible cortical necrosis. Early detection of renal failure in newborns with HIE is critical for adequate uid and
electrolyte management, as a stable electrical milieu is critical. Many clinical and biochemical criteria are unreliable in this age range, making it
difcult to diagnose renal failure. As a result, the current study aimed to nd out the renal parameters and serum calcium levels in neonates with
perinatal asphyxia. Current study was hospital based prospective study conducted in the department o Material and Methods: f Paediatrics ,
SPMCHI, SMS Medical College, Jaipur from February 2021 to December 2022. In this study a total 100 participants were included. A detailed
clinical examination was taken to identify the appropriate for gestational age by applying the New Ballard score and birth weight. Renal
function parameters: urea, creatinine, and calcium were sent to the biochemistry lab by taking peripheral venous blood samples, initially within
24±6 hrs.. of birth and later at 48±6 hrs.. and 72±6 hrs. Data were analysed in SPSS v- 24. Anova test and Chi-square test were applied. p value
<0.05 was considered statistically signicant. Results: A statistically signicant decline was found in serum urea and serum creatinine level
from 24 hours to 72 hours while a statistically signicant increment was found in serum calcium level from 24 hours to 72 hours. A statistically
signicant gender and mode of delivery difference was found between different stage of HIE. Male newborn and LSCS were more in stage II and
III. Serum urea, serum creatinine level was statistically signicant increased while serum calcium level decreased as HIE stage increases at
different time interval. Neonatal renal insufciency is commonly caused by Conclusion: perinatal asphyxia. Serum calcium level and urea and
creatinine were found to associated with HIE stages so frequent measurements of serum calcium, urea and creatinine levels aid in the early
detection and management of renal failure
CORRELATION OF COLPOSCOPY WITH BIOPSY IN CASE OF ABNORMAL CERVICAL CYTOLOGY
Authors: Perhar Ramona , Nishad Sarika , Yadav Monika , Upadhyay Anupma
Published: July 2023

Background : Cancer cervix is the most common genital cancer among women in India. Wide Spread use of screening and conrmatory methods has Increased detection rate of preinvasive stage of disease. This study was Objectives: aimed to evaluate Correlation of pap Smear and colposcopy in detection of premalignant lesions of cervix and to nd out the role of colposcopy and its relation with cervical biopsy to evaluate abnormal cervical cytology. This prospective clinical study was Material and Methods : conducted over a period of one year from July 2022 to June 2023 in Gynecology OPD of SRN Hospital and KNMH, Prayagraj after taking approval from the institution Ethical committee with a sample size of 100 woaman with abnormal PAP Smear report. Out of total 100 Results: abnormal PAP Smear Cases ,underwent colposcopic and histopathological examination 35 % detected as non-specic cervicitis,24% detected as CIN I , 23% detected as CIN II and 15 % detected as CIN III and 3% detected as squamous cell carcinoma.In our study accurate estimation of colposcopy occurs in 73% cases ,in 9% patients colposcopicaly overestimated and 18% cases underestimated. The regular Conclusion: screening of population by Pap smear is cost effective method for early detection of premalignant and malignant cervical lesions .Colposcopy is better tool for the evaluation of women with abnormal Pap smears, unhealthy cervix, and seems to be more accurate in detecting CIN. colposcopy eliminates the need for repeated follow up as in pap smear . Hence, colposcopy with biopsy should be incorporated in women with abnormal cervical cytology
ASSESSEMENT OF CARDIOVASCULAR RISK FACTORS AND BMI AMONG PROFESSIONAL COMMERCIAL DRIVERS IN SAGAR DISTRICT OF CENTRAL INDIA: A CROSSECTIONAL STUDY.
Authors: Mishra Satyendra , Kiran Naagar Jagrati , Jha Anju , Mishra Nitu , Saad Talha , ilyas Mohammad
Published: July 2023

Introduction : The commercial professional drivers are at risk of developing diabetes, hypertension and obesity due to
the nature of their work as they tend to go early, work for many hours , have irregular dietary habits and sleep pattern and
sedentary lifestyle.The study sought to determine the known risk factors in order to better clarify the burden of this health issue in Sagar district of
Central India. A crossectional descriptive and analytical study was conducte Method : d among 496 commercial professional drivers and blood
sugar, blood pressure and height and weight was measured . The life style related risk factors were assessed using semistructured questionnaire
and also dietary pattern was assessed. The student T test and Chisquare test were used for statistical analysis. The youngest person was 22 Results:
years old and oldest was 66. The mean age was 39.55±12.53 years. The mean number of years for which they were in job was 17.5 ± 9.62 and they
worked for a mean duration of 13.56 ± 2.87 hours. The other risk factors found was alcohol intake and smoking,irregular dietary pattern, lack of
physical activity and sleep. There is a need for intervention to promote a heal Conclusion: thy life style and curb the prevalence of diabetes,
hypertension and overweight to improve the health of drivers and safety of passenger
ANALYSIS OF HEALTH HAZARDS AND SAFETY MANAGEMENT IN CONSTRUCTION INDUSTRY
Authors: Bang Mayuri , Nemade Pravin
Published: July 2023

The building industry's contribution to economic development benets every nation on the planet greatly. Due to its laborintensive nature, construction work presents employment opportunities for numerous trained, semi-skilled, and unskilled workers. The purpose of this study is to evaluate how well construction sites manage worker health and safety. It aims to identify the scope and causes of occupational illnesses, accidents, and fatalities as well as the difculties in managing occupational safety and health on building construction sites. Lack of a safety and health policy, a lack of personal protective equipment, inadequate training, a shortage of safety and health specialists, and inadequate risk assessments are the main barriers to managing occupational safety and health on construction sites. A systematic approach to labor inspection is also lacking, and occupational accidents are not accurately reported or recorded. To address the occupational safety and health issues that face workers on building construction sites, it is absolutely essential to provide welfare facilities, personal protective equipment, and worker training on safety procedures. By implementing current legislation and creating occupational safety and health regulations, the government must show its political commitment.
OUTCOMES OF IMPLEMENTING NADI SHODHANA PRANAYAMA IN ROUTINE PER DIEM
Authors: Joshi Naina , Kumar Panda Srikanta
Published: July 2023

Ashtang Yoga is Patanjali's classication of classical yoga, as in his yoga sutras. It comprises of eight limbs, one of them
being pranayama. Pranayama is the term for all yogic breathing exercises. It is also stated as the art of breath control. Nadi
Shodhana Pranayama or Alternate nostril breathing is one type of pranayama. It is the focused practice of breathing through alternate nostrils, one
side at a time. Nadi means channels and Shodhana means cleansing, therefore the term stating to as practice which cleanses the channels of body. It
is advised to be practiced before initiating other types of pranayama as when the channels are full of impurities, the vital air does not pass through
them. As an outcome of this practice, the nadis are puried, and the individual can control and retain his breath. Daily practice of this pranayama
has multiple benets on overall health, especially on the cardiovascular apparatus. Therefore, it should be inculcated in daily routine for maximal
benets
ANALYSIS BY DNA OLIGO-ARRAYS MOLECULAR CYTOGENETIC IDENTIFIED A SIZE OF 40 MB RING X CHROMOSOME 46/45 MOSAIC GIRL SUSPECTED FOR TURNER SYNDROME
Authors: Chauhan Pooja , Kumar Rai Amit
Published: July 2023

Purpose: A number of people meet with the infertility in their reproductive ages. If we list out the reasons of infertility state there are a number of problems. Among these problems, primary amenorrhea is a condition that leads to many other diseases/symptoms. Ring chromosome of X chromosome is one of the structural anomalies which are associated with manifestation of primary amenorrhea due ovarian dysgenesis. Ring chromosome may be present in mosaic form or present in all cells of an individual. Clinical Methods: history of 14 years girl was recorded. Around 5 ml peripheral blood was drawn in a sterilized syringe under complete aseptic condition. Whole blood culture was set with 0.5 ml peripheral blood for cytogenetic experiments like G banding, Karyotyping including FISH. Rest of the peripheral blood was used for extraction of genomic DNA for DNA HD-oligo array. Anal Results: ysis by DNA oligo-arrays molecular cytogenetic identied a size of 40 Mb ring X chromosome 46/45 mosaic girl suspected for Turner Syndrome Conclusion: It was concluded that ring (X) chromosomes lead to phenotypic heterogeneity which varies remarkably with its gene content and level of mosaicism.
A COMPARATIVE ANALYSIS OF SEROPREVALENCE OF SYPHILIS DETECTED BY RAPID PLASMA REAGIN TEST AND ENZYME LINKED IMMUNOSORBENT ASSAY IN BLOOD DONORS ATTENDING A REGIONAL BLOOD TRANSFUSION CENTRE
Authors: Johny KJ Leya , VJ Fathima , S Mayadevi. , P. S Shaiji.
Published: July 2023

Background: Syphilis screening methodology in all Government hospitals in state of Kerala was changed from the Rapid Plasma Reagin (RPR) method to Enzyme linked immune sorbent assay (ELISA) in August 2021. We compared the prevalences of syphilis in blood donors before and after this change in Government Medical College ,Trivandrum. Methods: Samples positivity under RPR (2019 January to 2021 July ) and ELISA (2021 August to 2022 December) screening were compared. Results: A total of 113059 donations were analysed. Seroprevalence in the RPR testing period was 106/78537 (1.4 %) and in ELISA was 74/34522(2.1%) Conclusions: Frequency of seroreactive cases were signicantly higher when tested with ELISA.
IMMUNOHISTOCHEMICAL STUDY OF P53 AND KI-67 EXPRESSION IN SURFACE EPITHELIAL TUMORS OF OVARY
Authors: Kasundra Khushbu , Jadav Kirit , Patel Pulkit , Patel Zankar
Published: July 2023

Introduction: Ovarian cancer accounts for a signicant number of deaths from female genital tract malignancies worldwide. Among ovarian
neoplasm, 2/3rd of tumors are of surface epithelial origin. Most common mutated tumor suppressor gene in human malignancies is p53.
Overexpression of p53 gene has been claimed to be associated with poor prognosis. Assessment of cellular proliferation marker (Ki-67 labelling
index) has diagnostic and prognostic signicance in ovarian neoplasm. A study wa Material and Method: s conducted at tertiary care hospital in
Central Gujarat, India. Immunohistochemistry was performed on 51 cases and results were noted. Out of 51 cases, 31 were benign, 4 were Results:
borderline and 16 were malignant. P53 expression was highest in malignant and borderline tumors. Mean Ki-67 LI was highest in malignant
tumors (45%). Higher expression of Ki-67 in malignant surface epithelial ovarian tumors Conclusion: emphasizes its role in prognosis of tumors.
AFRS IN A TERTIARY CARE HOSPITAL: OUR EXPERIENCE
Authors: Banjara Hansa , Chandrakar Ankur , Gajendra Durgesh , Verma Jyoti
Published: July 2023

Introduction: The incidence of acute fungal rhinosinusitis has dramatically increased after Covid pandemic. Extensive use of steroids in Covid-19
management, associated diabetes mallitus or comorbidities can also suppress immunity of the patient thus allowing opportunistic fungal infections
to colonise. Mucor, Rhizopus and Absidia are the main types of fungal infection affecting nose, paranasal sinuses, orbits or brain leading to life
threatening outcomes or morbidities. A Retrospective study of 53 patients with s Materials and methods: uspected invasive fungal infection who
presented to the ENT department, were included and evaluated clinically, radiologically, and endoscopically. Tissue samples from suspected sites
were taken for KOH mounting and microscopy for conrmation of fungus. A total of 53 patient Result: s were included. Out of 53 patients 75.47%
were male with average of 50 Years. Total 34 patients were in covid positive status. Major symptoms were Facial, orbital, nasal and Intracranial.
Main risk factors for disease were DM, oxygen and steroid therapy and comorbidities. Total 79.25% were found positive for fungus on direct
microscopy after KOH mounting. Conclusion: In our study maximum patients presented with combined ENT, Orbital & Neurological
manifestations. Diabetes was most common co-morbidity found in almost all patients. Uncontrolled diabetes and over-zealous use of steroids are
the main factors found to be aggravating the illness. Early and proper diagnosis, required surgical interventions and anti-fungal treatment should be
sought for management.
CLINICO-HEMATOLOGICAL EVALUATION OF ANEMIA IN PREGNANT WOMEN
Authors: Sahu Sumanlata , Rani Deepa , Sachan Shikha , Agrawal Priyanka , Prashant Meena Lalit
Published: July 2023

Background- According to the WHO, the prevalence of anaemia in pregnant women in developed countries is 14%; in developing countries, it is 51%; and in India, it varies from 65% to 75%. To study the complete clinico-haematologi Aims- cal prole of pregnant anaemic women in different trimester, analyse the characteristics of various types of anaemia, predict the role of Mentzer index for differentiating iron deciency anemia and to screen for cases of thalassemia in eastern Uttar Pradesh. This was Methods: a prospective observational study conducted on 200 pregnant anaemic women. Blood samples were taken in an EDTA vial for a complete blood count, screening for thalassemia, and peripheral blood smears were examined along with their complete clinical and obstetric history. Out of Results: 200 cases of anaemia, 44% of patients have normocytic normochromic anaemia and 31% have microcytic hypochromic anaemia. The sensitivity and specicity of Mentzer index for iron deciency anemia in our study was 98.25% and 16.67%. The risk factors for anaemia noted in this study are low social and economic status, low occupational status, low educational status, and demographic status. In this study, anaemia was more commonly found in the third trimester of pregnancy. Conclusions: With improved social and economic conditions, early detection, good antenatal care, awareness regarding available treatment, a healthy diet, routine antenatal counselling, and adequate iron supplementation, anaemia in pregnancy can be avoided.
GRADING BRAIN TUMORS USING ADVANCED MAGNETIC RESONANCE IMAGING SEQUENCES
Authors: K Harish , J Divya , Jacqueline Saulam , Vamsi Krishna Reddy B
Published: July 2023

Background: Conventional MR imaging techniques and a variety of advanced techniques have a role in clinical practice or are the subject of research. This study aimed to advance MRI sequences: perfusion, DTI, and spectroscopy and to evaluate the role of advanced MRI sequences for grading intra-axial and extra-axial brain tumors. A hospital-based retrospective obse Methods: rvational study of 30 patients was conducted in Tumkur, Karnataka, India. Conventional T1, T2, FLAIR, DWI & ADC, and SWI sequences were used. The advanced MRI imaging techniques perfusion study, spectroscopy, and diffuse tensor imaging were used. To compare the conventional MR imaging parameters based on the tumor grades we performed a Chi-square test. We also conducted Fisher exact test when the assumptions of the Chi-square test were violated. Results: The mean age of the patients was 42.5 years. Most of the patients had tumors found in the brain's supratentorial region compared to the infratentorial region (86.7% vs. 13.3%). About 60% of the patients were diagnosed with high-grade tumors. Among our studied patients, all the high-grade brain tumors were detected in patients over 30 years of age whereas half of the patients diagnosed with low-grade tumors were 15 to 30 years of age. Males were found to have higher high-grade tumors compared to females (58.3% vs. 44.4%). Both high and low-grade tumors were found higher in the supratentorial regions of the brain. The mean value of relative cerebral blood volume (rCBV) was found signicantly higher in high-grade tumors as compared to low-grade tumors (4.45 vs. 0.62). This study has demonstrated t Conclusion: he utility of advanced MRI imaging can effectively differentiate different grades of brain tumors.
COMPARATIVE STUDY OF PFNA AND PFNA2 IN AN UNSTABLE INTERTROCHANTERIC FRACTURE A RETROSPECTIVE STUDY OF 50 CASES.
Authors: Reddy Tarun , Ismail Hathiwale Mohammad , Gajabar Samarin , Kodela Tejdeep
Published: July 2023

Introduction: Geriatric hip fractures are one of the commonest fractures worldwide, and treating unstable intertrochanteric fractures in geriatric age groups is always challenging due to osteoporosis these are more common in females, and these fractures are complicated with associated comorbidities. Today operative treatment has largely replaced conservative management and the goal is to achieve stable xation and early mobilization. : the study was conducted on 50yrs elderly with unstable intertrochant Materials And Methods eric fractures in which 25 cases were treated with PFNA and 25 cases were treated with PFNA2 from October 2020 to October 2021. we observ Conclusion: ed that both PFNA and PFNA2 perform well, showing equally good functional and radiological outcome, PFNA2 offers the advantages of better bone purchase in patients with osteoporotic bone and has the advantage of minimal incision, both offer excellent result in terms of mechanical stability and union rate.
ESTIMATION OF GESTATIONAL AGE AND IDENTIFICATION OF PREMATURE NEONATES USING NEONATAL ANTHROPOMETRY – OCCIPITOFRONTAL CIRCUMFERENCE AND CROWN HEEL LENGTH
Authors: K N Hamsa , S Purnima
Published: July 2023

Background: Prematurity is an important contributor to neonatal mortality in India. Gestational age assessment is done by the conventional method
“New Ballard Technique” which is more subjective and requires Pediatricians for assessing, and it is difcult in peripheral centers where the availability
of Pediatricians is less. We aimed to determine if anthropometric measurements like occipitofrontal circumference and crown–heel length of the
neonate can be used for assessing the Gestational age of neonate, as these measurements are easy to measure by untrained persons in the periphery.This
helps in early intervention, if the neonate in preterm and can reduce mortality of preterm neonates. Objectives: To estimate Gestational Age (GA) of
neonates using Occipitofrontal Circumference(OFC) and Crown Heel Length(CHL). An Observational study Study Design: Participants: All
neonates delivered in BGS GIMS, Bangalore during the study period. OFC and CHL have a good correlatio Results: n with Gestational age with r-value
0.751 and 0.799. The regression equation derived were Predicted GA = 1.7143 (OFC) + (-19.7143) andPredicted GA = 1.2 (CHL) + (-20.4) respectively
for OFC and CHL. Multiple regression gave equation Predicted GA = 0.311 (OFC) + 1.108 (CHL) + (-25.841) which is statistically signicant.
Conclusion: OFC and CHL are quick and easy methods which can be used as simple tools for predicting Gestational Age. This can help in identication
of preterm neonates by peripheral health care workers and to intervene early and reduce mortality of neonates.
CARDIOVASCULAR DYSFUNCTION IN CIRRHOSIS AND ITS RELATION TO SEVERITY OF CIRRHOSIS.
Authors: Ahmed Waseem , Mahajan Aakriti , Parotra Aabhasha , Lone Adnan
Published: July 2023

Liver cirrhosis is associated with a wide range of cardio vascular abnormalities. Cardiac dysfunction in patients with cirrhosis, contributes
signicantly to mortality and morbidity. Circulatory abnormalities are predominantly due to liver derived toxic factors causing arterial dilation and
hyper dynamic circulation. The present prospective, observational cross-sectional study was conducted in the Department of Medicine,
Government Medical College, Jammu for a period of one year, w.e.f 1st November 2020 to 31st October 2021 with the aim to analyse the
cardiovascular dysfunction in cirrhosis and to determine its relation to severity of cirrhosis. A total of 100 patients were included in the study.
Detailed clinical evaluation including history was recorded and required investigations and tests was done. Descriptive data was expressed as range
and mean standard deviation with the help of SPSS software version 24. In the present study, there was a male predominance (81%) over females
(19%). The male female ratio was 4.26:1. Most of the subjects belonged to the 41-60 years age group (n=48, 48%) followed by >60years age group
(41%) and minimum subjects (11%) belonged to the 18-40 years age group. It was seen that 69% had alcohol as an aetiology, followed by hepatitis
C (16%), HBV (10%), and Wilson disease (5%). The study concluded that Indian patients with cirrhosis do have diastolic dysfunction
A RANDOMIZED CONTROLLED TRIAL ON THE EFFICACIES OF TOPICAL METRONIDAZOLE, DILTIAZEM AND LIGNOCAINE IN IDIOPATHIC CHRONIC ANAL FISSURE
Authors: Mishra Kajal , Ahmad Shabi , Chandra Jha Abhinav , Mittal Gaurav
Published: July 2023

Aim and objectives: To evaluate and compare the effects of topical application of metrogyl ointment, diltiazem ointment and lignocaine in the healing of chronic anal ssure (CAF). Materials and method: This Randomised controlled trial was conducted in the Department of General Surgery, Swaroop Rani Nehru Hospital, Prayagraj, after obtaining clearance from hospital Ethics Committee. The drugs were applied over thessure twice a day. Healing of the ssure in terms of complete epithelialization, and reduction of pain (measured by visual analogue score) were noted. VAS score was rated from 0-100 in terms of pain sensations as used in another similar study. Any side effects of the used drugs were recorded. The patients were followed up at 2, 4 and 8 weeks of initiation of treatment for assessing the outcomes. Results: It was noted that the VAS score were signicantly lower with Metronidazole in comparison to Lignocaine at 4 weeks; whereas at 8 weeks, it was signicantly lower in Diltiazem group as compared to Lignocaine group. There was a signicant difference in the healing between Diltiazem and Lignocaine (p=0.0006) and Metronidazole and Lignocaine (p=0.007) but no statistical difference between Diltiazem and Metronidazole (p=0.667). Headache was signicantly more in Diltiazem group (24%) and burning sensation was signicantly more with the use of Metronidazole. (p=0.022). Conclusion: Diltiazem and metronidazole are equivalent to treat anal ssures for relieving pain and healing, both of which are better in comparison to lignocaine.
A CROSS SECTIONAL STUDY TO EVALUATE EXPRESSION OF ESTROGEN RECEPTOR, PROGESTERONE RECEPTOR AND HER2/NEU IN OVARIAN TUMOURS
Authors: Pachori Saroj , Kumar Upadhyay Tapendra , Pachori Parmendra , Sharma Divya , Kumar Sharma Rajendra
Published: July 2023

Ovarian cancer is the second most common gynaecologic malignancy and the fth leading cause of cancer death in women in developed countries1. More effective treatment regimens like "targeted" oncologic therapies must be developed to improve morbidity and reduce mortality in ovarian cancer patients. Estrogen receptors and HER2/neu are two such targets. The purpose of present study is to study the expression of estrogen receptors, progesterone receptors and Her2/neu in ovarian tumours. This was a Laboratory Methods: based cross sectional study conducted between August 2021 to December 2022 on 70 Oophorectomy specimen in 10% buffered formalin in the department of pathology, SMS Medical College, Jaipur. H&E and IHC for ER, PR and Her2/neu done. ER, PR and Her2/neu receptors pos Results: itivity was highest in surface epithelial tumours cases followed by germ cell tumours, and sex cord stromal tumour. In HIGH GRADE, (mainly serous carcinomas) the ER receptor was present in 100% of the cases, the PR receptor in 76.92%, and the Her2/neu receptor was present in 100% of cases. This study reveals Conclusion: that ovarian cancer are inuenced by classic variables such as histologic type, grade and stage of tumour. This leads to development of targeted oncologic therapies that might be more effective and less toxic. Estrogen and Her2/neu are two such targets
KNOWLEDGE, ATTITUDE, AND AWARENESS REGARDING HPV INFECTION AND VACCINATION AMONG FEMALE IT PROFESSIONALS OF A COASTAL CITY – A CROSS-SECTIONAL STUDY.
Authors: Narasimha Manoj Turlapati , Vijaya K
Published: July 2023

Aims: The aim of this study is to assess to assess knowledge, attitude, awareness of human papilloma virus (HPV) and HPV vaccination among the female IT professionals. A cross-sectional survey of women was conducted in Vi Materials And Methods: sakhapatnam to assess the awareness of cervical cancer and attitude of Papanicolaou (Pap) test and HPV vaccine. The sample size of the population was 171, and a pre-tested questionnaire was administered to them. Majority of the participants (65.5%) were aware tha Results: t cervical cancer can be prevented. As far as vaccination was concerned, 62.1% were familiar with the availability of CERVAVAC vaccine. However, very few participants (16.7%) had completed a full course of vaccination while (77.1%) have not initiated yet. The high awareness am Conclusion: ong females of IT sector about cervical cancer and acceptability of vaccine programs, if done free of cost, shows a positive trend. The only inhibition about HPV vaccine was primarily due to concerns about post vaccination complications. However, inclusion of HPV vaccine in Government-sponsored immunization program would go a long way in increasing the uptake of the vaccine.
ANTI-MICROBIAL PROPERTIES OF FLAVONOIDS FROM ABUTILON INDICUM AGAINST PSEUDOMONAS AERUGINOSA AND STAPHYLOCOCCUS AUREUS
Authors: Sunil Mannala , Mukundrao Chawre Sanjeevani , Amrut Bansode Amit , Srinivasa Rao Meesala.
Published: July 2023

Developing new antibiotics, it is becoming increasingly difcult, with greater time-consuming and more expensive to develop new antibiotics, especially because emerging strains are becoming increasingly resistant to existing antibiotics. Phytochemically, avonoids are plant secondary metabolites with powerful therapeutic effects and there are several scientic evidences that plant avonoids are potent pharmacological agents. In this study, Effect of Flavonoids derived from the leaves of Abutilon indicum on bacterial growth and efux pump activity were tested on Pseudomonas aeruginosa and Staphylococcus aureus. A standard antibiotic ampicillin was comparable to the inhibitory effects of avonoids at 1.80 mg/mL of concentration on bacterial growth. The avonoids from Abutilon indicum had showed a MIC of 0.0036 mg/mL and an MBC of 0.96 mg/mL, making them the most effective against S. aureus and P. aeruginosa. It was proven that plant avonoids had bacteriostatic effects on P. aeruginosa and S.aureus. Abutilon indicum avonoids inhibited the drug efux pump susceptible in P. aeruginosa, which resulted in a 132% increase in Rhodamine-6G accumulations compared to the control. As a result, Leaf avonoids from Abutilon indicum exhibited antibacterial activity as well as the ability to inhibit the ATP-dependent transport of compounds across cell membranes, and these avonoids can be used as potential lead compounds for the development of plant-based antibacterial agents and their adjunct compounds.
EFFICACY AND SAFETY OF FRACTIONAL CO2 LASER RESURFACING IN ATRPOHIC FACIAL ACNE SCARS
Authors: Dutta Devankur , Kumari Singh Rinki , Saikia Suman , Barua Shyamanta
Published: July 2023

Background:Acne vulgaris is one of the commonest adolescent dermatoses with almost every patient having the risk of developing acne scars as a
sequelae. Atrophic scar is the most common type and management of which causes a therapeutic challenge. Presently fractional CO2 laser
resurfacing is regarded as one of the most effective available treatment. In a hospital based pros Methodology: pective observational study, 42
patients presenting with atrophic facial acne scarring were included in this study. Patients were most commonly in the age group 21-25 Results:
years with Male: Female ratio of 1:1.63. The most common subtype (48%) was combination scars (Box scar+ rolling+ ice pick) followed by
isolated rolling scar and box scar (19%) each. Majority presented with moderate severity (81%) with cheeks being the most common site of
involvement (100%) followed by temples (57%). A positive response with either good or excellent results was reported in 36 patients
corresponding to 85.7% of the study group. The study emphasizes on the role of fractional CO2 las Conclusion: er resurfacing in the treatment of
atrophic acne scars
INTRADUCTAL PAPILLOMA – A CASE REPORT AND REVIEW OF LITERATURE
Authors: Varshita Buddha Harika
Published: July 2023

Intraductal papilloma is a benign neoplasm that typically arises in the mammary glands of the breast. Similar growth pattern can also be observed in the salivary glands, where it is known as intraductal papilloma of the minor salivary glands. In this case report we are discussing about a 19 year old male patient where the tumor is characterized by a papillary growth pattern of the salivary gland duct epithelium, and it is often associated with dilatation of the ducts. The epithelial cells that line the papillae may show variable degrees of dysplasia, but they are typically benign in nature. Histopathological examination with appropriate immunohistochemical panels may be used to help distinguish intraductal papilloma from intraoral cystic lesions and other benign or malignant tumours.
MEAN PLATELET VOLUME (MPV) AS A RISK STRATIFICATION TOOLAND AN EARLY PROGNOSTIC MARKER IN ACUTE ISCHEMIC STROKE: AN OBSERVATIONAL STUDY FROM TERTIARY CARE HOSPITAL IN NORTH EAST INDIA
Authors: Kumar Nikhil , Das Polok , Bhattacharjee Prithwiraj , Laskar Mehjabin , Chakraborty Alok
Published: July 2023

Introduction: Stroke is one of the leading causes of disability and death worldwide. A stroke or cerebrovascular accident is dened as “an abrupt onset of neurological decit that is attributable to a focal vascular cause.” A majority of strokes are ischemic in origin (80%), which can be either thrombotic or embolic in nature. Activation of platelets play an important role in the process of atherosclerosis. The mean platelet volume (MPV) is a laboratory marker associated with platelet function and activity. Increased MPV in thromboembolic disease is reected as an important risk factor. The aim of the study is to assess MPV in acute ischemic cerebrovascular stroke and, furthermore, to nd out its diagnostic value in an acute setting to help risk stratication in patients with ischemic stroke. Material And Methods: The present study was conducted in Department of General Medicine, SMCH from 1st June 2021 to 31st May 2022, with the aim of evaluating the role of Mean platelet volume (MPV) in determining the severity and prognosis of Acute Ischemic stroke. It was a hospital based observational study comprising of 100 patients diagnosed with acute ischemic stroke who presented to the hospital within 48 hours of onset of symptoms. Equal number of age and sex matched control group was taken after fulllment of inclusion and exclusion criteria. The diagnosis of stroke was made clinically according to World health organization and conrmed by brain CT and MRI when needed. Blood samples were collected and MPV was assessed within 2 hours after admission. The severity of ischemic stroke was assessed using Modied Rankin scale (MRS). Results: In this study, MPV value was found to be signicantly high in stroke patients (11.26 ± 1.22 fL) as compared to control group (9.98 ± 1.22 Fl, p value<0.00001). The MPV value was found to be signicantly high in patients with higher MRS score in comparison to those with lower scores (p value=0.000011). Higher MPV values were also associated with poorer functional outcome at Day 7, increased length of hospital stay, increased ICU admissions and in-hospital mortality. Conclusion: Platelet size (MPV), a marker of platelet function is a physiological variable of hemostatic importance. Higher MPV values were associated with more severe stroke and worser outcome. MPV can predict the outcome among stroke patients in terms of morbidity and mortality. In developing countries with limited resources, MPV can be a useful and cost effective biomarker in evaluation and prognostication of patients admitted to hospital with acute ischemic stroke.
IMPLEMENTASI SISTEM INFORMASI DATA PELAKU USAHA PERIKANAN BUDIDAYA PADA DINAS PERIKANAN KOTA KUPANG
Authors: Ndoen Frensile Susanti , Boru Meiton , E. A. Pah Clarissa
Published: July 2023

Pelaku usaha perikanan budidaya pada Dinas perikanan kota Kupang tahun 2022 tercatat sebanyak 649 orang yang terbagi dalam 55 kelompok pelaku usaha dengan 566 anggota dan 83 pelaku usaha perorangan. Proses pengolahan data pelaku usaha perikanan budidaya yang dioperasikan melalui Microsofts Office Excel (Ms. Excel) belum optimal karena sering ditemukan beberapa kendala yaitu terjadinya duplikat data, sulit menghitung jumlah seluruh pelaku usaha,  sulit merekap data dalam jumlah yang banyak karena data yang disimpan tersebar dalam beberapa file excel sehingga menyulitkan petugas untuk pembuatan laporan data pelaku usaha perikanan budidaya. Oleh karena itu, tujuan penelitian ini membuat sebuah sistem untuk membantu petugas dalam mengelola data pelaku usaha perikanan budidaya. Metode yang digunakan dalam penelitian ini adalah metode Waterfall karena kelebihannya adalah kualitas dari sistem yang dihasilkan akan baik karena pelaksanaannya dilakukan secara bertahap. Sistem ini menghasilkan laporan data kelompok, data pelaku usaha, data usaha, data kolam data bantuan, data produksi, data tanda usaha, data pelatihan, dan histogram jumlah pelaku usaha berdasarkan jenis kelamin, jumlah usaha penerima Kartu Pelaku Usaha Bidang Kelautan Dan Perikanan (KUSUKA), jumlah usaha per papan nama kelompok, jumlah pelaku usaha per kecamatan, jumlah usaha per kecamatan dan skor rangkuman jumlah pelaku usaha perikanan budidaya. Hasil pengujian black box yang dilakukan oleh 3 responden terhadap 12 menu menunjukkan bahwa semua fungsional sistem berfungsi sesuai dengan yang diharapkan.