bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of peer support in coping and adjustment to dialysis and transplantation: Study protocol
Authors: Winterbottom Anna , Wood Eleri , Mooney Andrew , Bucknall Keith , Bekker Hilary L.
Published: February 2025

Introduction

People with kidney failure receiving dialysis or kidney transplantation find it difficult to adapt to treatment related routines and restrictions, and feel frustrated when their expectations aren’t matched by their lived experience. Health professionals provide information to help people prepare for kidney treatments, but it may be that ‘peer supporters’ - people who live with kidney disease - can provide more easily understood and relevant information. This study will explore how learning from peer supporters might improve the experience of treatment, after dialysis initiation and post-transplantation, by helping them to better understand what to expect from treatments.

Methods

Two mixed methods studies including in-depth interviews and questionnaires. In each study, participants will be recruited at two timepoints, before commencing dialysis or transplantation, and 6 months later. Questionnaires and interviews will explore expectations and the lived experience of treatment, and if peer support impacts on adjustment and coping with treatment. Participants will be recruited from two large teaching hospitals in the North and South of England, where one has access to a formal kidney peer support program.

Discussion

Delivering peer support in kidney units is increasingly popular, yet provision is inconsistent and generally low quality. Providing an evidence base for it’s use will help guide the optimal development of peer support programmes and efficient allocation of peer resources. A report will be produced to summarise the our findings, which will help kidney units better help people with kidney failure prepare for kidney treatments.
In vitro antibiofilm efficacy of ertapenem, tobramycin, and moxifloxacin against biofilms grown in a glass bead or CDC Biofilm Reactor®
Authors: Gilmore Annika L. , Vu Helena , Martinez Travis , Peniata Lousili , Kawaguchi Brooke , Armbruster David A. , Ashton Nicholas N. , Williams Dustin L.
Published: February 2025

Laboratory grown biofilms are used to simulate bacterial growth in diverse environmental conditions and screen the effectiveness of anti-biofilm therapies. Recently, we developed a glass bead biofilm reactor that utilizes low broth volume to provide high-throughput biofilm growth for testing and translation across the research continuum (e.g., benchtop assays to preclinical models). Bioburden per mm2 surface area of Staphylococcus aureus and Pseudomonas aeruginosa biofilms were comparable on beads and CDC Biofilm Reactor® coupons. In this study, we hypothesized that biofilms grown on beads would be more susceptible to ertapenem, moxifloxacin, and tobramycin than those grown on coupons. Results indicated a significant reduction in S. aureus bioburden on glass beads compared to glass coupons following treatment with ertapenem (p = 0.005) and tobramycin (p = 0.014). P. aeruginosa biofilms had smaller differences in antibiotic response between the two systems. There was a significantly greater reduction in bead P. aeruginosa biofilm than coupon when treated with tobramycin (p = 0.035). This work offered insight into how the bead biofilm reactor could be used as a tool for antibiotic screening and translation across the continuum of in vitro to in vivo systems that support development of antimicrobial technology.
Pathology and parasitology of free-ranging coyotes from Tennessee and South Carolina
Authors: Baker Eliza , Dennis Michelle , Miller Debra , Su Chunlei , Rosypal von Dohlen Alexa , Abouelkhair Mohamed A. , Hamer Sarah A. , Jensen Alex , Gerhold Richard
Published: February 2025

Coyotes are exposed to many parasites and pathogens of veterinary and zoonotic concern. To assess the prevalence of the diseases caused by these microbes, we opportunistically obtained coyote samples from a variety of sources including a GPS collaring study, rabies testing facilities, wildlife resources agents, and road-side mortalities. We performed necropsies, serological testing, fecal flotations, and molecular analyses on coyotes from Tennessee and South Carolina. Dirofilaria immitis (heartworm) infected 46% (41/89) of coyotes and was associated with eosinophilic alveolitis and arteritis. Paragonimus kellicotti, a zoonotic lung fluke, was found in 24% (17/71) of Tennessee coyotes, including one coyote with extrapulmonary infection affecting the liver and lymph nodes. Trichinella spp., a zoonotic nematode, was present in 17% (12/71) of Tennessee coyotes but was not associated with muscular inflammation. Sarcoptes scabiei, the causative agent of sarcoptic mange, was detected in one Tennessee coyote. Most coyotes (86% [90/105]) were seropositive for Toxoplasma gondii, while 8.5% (9/106) were seropositive for Trypanosoma cruzi, an emerging zoonotic, vector-borne parasite. This study demonstrated that coyotes are commonly exposed to numerous parasites and pathogens that affect people and pets and are excellent sentinels for these diseases.
Modeling daily evapotranspiration time series based on Non-Linear Autoregressive Exogenous (NARX) method and climate variables for a data-deficient region
Authors: Necesito Imee V. , Lee Junhyeong , Kim Kyunghun , Kang Yujin , Quan Feng , Kim Soojun , Kim Hung Soo
Published: February 2025

For flood-prone, developing nations where hydrological data is scarce, an innovative methodological approach is essential. This study aims to explore the potentiality of modelling daily evapotranspiration time series by checking causal relationship among the available climate variables in a flood-prone, data-deficient region like Samar in the Philippines. First, to verify if the available variables (rainfall, air pressure and the four (4) Niño Sea Surface Temperature (SST) Indices) have direct effects to evapotranspiration, a causality test called Convergent Cross-Mapping (CCM) was used. Interestingly, only the Niño SST indices and air pressure were found to have direct effects. Results showed that air pressure and the four (4) Niño SST Indices when combined with Non-Linear Autoregressive Exogenous (NARX) method, can effectively model evapotranspiration. This study raises a significant advancement in evapotranspiration modelling as it is the first to model and pinpoint the potentiality of causal relationship of air pressure and the four (4) Niño SST Indices to daily evapotranspiration time series. This method is found to be potentially suitable for disaster-prone regions where hydrological data is limited.
Gains vs losses in pay-for-performance: Stated preference evidence from a U.S. survey
Authors: Trogdon Justin G. , Khanderia Aveena , Brignole Kathryn , Lewis Jodi A. , Licciardello Queen Tara
Published: February 2025

Background

Pay-for-performance (P4P) incentives can be paid as a bonus (gain) or a penalty (loss). Diminishing marginal utility of wealth suggests that, starting from the same initial wealth, individuals dislike losses more than they like equivalent gains.

Objective

This study reports the minimum financial gain or loss required to motivate primary care providers and clinical staff to try to increase their human papillomavirus (HPV) vaccination rates.

Data

In 2022, we conducted a national U.S. survey through WebMD’s Medscape Network of clinical staff working in primary care clinics that provided HPV vaccination to children ages 9 through 12 years (N = 2,527; response rate = 57%).

Methods

We randomized respondents to one of two hypothetical HPV vaccine incentive designs: a bonus for reaching an unspecified target HPV vaccination rate and a penalty for failing to reach the unspecified target. The primary outcome is the self-reported smallest incentive amount (U.S. dollars) that would motivate participants to try and increase their HPV vaccination rates. We tested for differences across P4P designs using unadjusted responses and linear regressions adjusting for clinic and respondent characteristics. We also tested for heterogeneous responses by experience with incentizves, training, and rurality.

Results

The mean amount required to motivate effort was $2,155 in the gain P4P design and $1,185 in the loss P4P design (unadjusted difference =  $970 [p < 0.001], adjusted difference =  $967 [p < 0.001]). There were no heterogeneous effects by rurality or experience with incentives. Physicians reported the highest differences (in dollars) between gain and loss P4P designs.

Conclusions

Stated preference data from primary care clinical staff suggests that effective P4P incentives could be half as large if designed as losses rather than gains.
Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition
Authors: Wang Jiayi , Brückner Nadine , Weissmann Simon , Günther Thomas , Zhu Shuyong , Vogt Carolin , Sun Guorong , Guo Rongrong , Bruno Renzo , Ritter Birgit , Steinbrück Lars , Kaufer Benedikt B. , Depledge Daniel P. , Grundhoff Adam , Viejo-Borbolla Abel
Published: February 2025

Varicella zoster virus (VZV) is a human-specific herpesvirus that establishes latency in peripheral neurons. The only transcripts detected in infected human trigeminal ganglia (TG) obtained shortly after death correspond to the VZV latency-associated transcript (VLT) and associated VLT-ORF63 splice variants. In vitro studies showed that VLT-ORF63 is translated into a protein (pVLT-ORF63) that induces VZV transcription. The mechanisms that lead to this restricted gene expression and the transition to lytic replication remain unknown, partly due to the difficulty of working with human neurons. In this study, we addressed whether the neuroblastoma-derived cell line SH-SY5Y could serve as a model to investigate the mechanisms that lead to repression of VZV gene expression followed by reactivation. VZV productively infected differentiated SH-SY5Y (dSH-SY5Y) whereas incubation with acyclovir (ACV) inhibited virus replication and induced a progressive repression of the virus. Upon removal of ACV there was production of viral particles in a subset of cells, while others contained non-replicating VZV genomes and VLT-containing transcripts for at least 20 days post-infection (dpi). Exogenous expression of VLT-ORF63 induced productive infection, suggesting that the non-replicating and repressed genomes remained functional. Interestingly, histone deposition was undetectable at VZV genomes in quiescently infected dSH-SY5Y cells, pointing to a potential novel mechanism leading to VZV repression in this neuronal setting.
Gen Z's Perspective on Balaclava Hijab Trend
Authors: Auhaina Adillya Kafilla , Rodiah Ita
Published: February 2025

Abstract: This study aims to understand and explore the controversial issue of wearing balaclava as a jilbab among Generation Z. The research method used is a qualitative descriptive research approach, with data collection techniques of observation, interviews, and documentation, and the technique of determining research informants using accidental sampling. The result of this research is that balaclava is a head covering worn by British soldiers when on duty in winter. Over time, balaclava has become very popular among motorcycle lovers. balaclava is used as a self-protection tool by motorcyclists to protect themselves from the wind and dust that blow strongly while driving. Nowadays, balaclava is becoming a trend among Indonesian hijabers, because of its unique and practical model. Muslim women use balaclava as a hijab style to look fashionable. However, the use of this jilbab has caused various controversies among Gen Z. There are some who agree with the use of the jilbab. There are some who agree with the use of this jilbab because it is simple and fashionable, but other opinions say that balaclava is considered not following Islamic law because it does not cover the aurat perfectly.Abstrak: Penelitian ini bertujuan untuk memahami dan mengeksplorasi isu kontroversial penggunaan balaclava sebagai jilbab di kalangan Generasi Z. Metode penelitian yang digunakan adalah pendekatan penelitian deskriptif kualitatif, dengan teknik pengumpulan data melalui observasi, wawancara, dan dokumentasi, serta teknik penentuan informan penelitian menggunakan accidental sampling. Hasil penelitian menunjukkan bahwa balaclava awalnya merupakan penutup kepala yang dikenakan oleh tentara Inggris saat bertugas di musim dingin. Seiring waktu, balaclava menjadi sangat populer di kalangan pecinta sepeda motor. Balaclava digunakan sebagai alat pelindung diri oleh pengendara motor untuk melindungi diri dari angin dan debu yang berhembus kencang saat berkendara. Saat ini, balaclava menjadi tren di kalangan hijabers Indonesia karena modelnya yang unik dan praktis. Perempuan Muslim menggunakan balaclava sebagai gaya hijab untuk tampil modis. Namun, penggunaan jilbab ini menimbulkan berbagai kontroversi di kalangan Generasi Z. Ada yang setuju dengan penggunaan jilbab ini karena dianggap simpel dan modis, tetapi ada juga yang berpendapat bahwa balaclava dianggap tidak sesuai dengan hukum Islam karena tidak menutup aurat dengan sempurna.
Protección de datos personales, redes sociales y menores de edad
Authors: Brión Berdote Estela
Published: February 2025

En plena era digital, los más jóvenes pueden considerarse los principales usuarios de redes sociales desde edades verdaderamente tempranas. En efecto, desde la misma irrupción de estos espacios, los menores han interiorizado el manejo de estas plataformas en orden a saciar sus necesidades de comunicación y entretenimiento de un modo sin precedentes. Alentados por el entorno y dinámica que estos servicios predisponen, los menores se han aventurado a compartir infinidad de informaciones propias y de terceros de manera constante. Sin embargo, estos nuevos hábitos en línea erosionan la privacidad de los más jóvenes, en especial, desde la implementación por parte de los proveedores de redes sociales de técnicas de tratamiento de datos que emplean big data e inteligencia artificial con el fin de rentabilizar sus servicios. En ese sentido, a pesar de que el concepto de privacidad comprenda tanto el derecho fundamental al honor, intimidad personal y familiar y la propia imagen, así como el derecho a la protección de datos personales, esta monografía centra su estudio en el derecho a la protección de datos personales como principal herramienta de protección ante el implacable avance de la sociedad de la información. Concretamente, la presente obra se centra en analizar si la normativa de referencia, encabezada por la normativa sobre protección jurídica de la infancia, junto con la normativa sobre protección de datos personales, otorgan una protección reforzada a la información personal del menor cuando maneja estas plataformas como persona vulnerable y necesitada de especial protección. Por último, la investigación se propone plantear en cada epígrafe nuevas garantías normativas con el objeto de proteger de manera específica los datos personales del menor como usuario de estos servicios.
Factors Associated with Community Visits to Integrated Non-Communicable Diseases Development Posts (Posbindu PTM)
Authors: Nur’Ilmi Aulia , Manglapy Yusthin Meriantti , Iftita Magumi Avrora , Askar Muhammad Afiq
Published: February 2025

Background: Non-communicable diseases are encountered quite often in productive age. Early detection efforts through Posbindu-PTM must be optimized, considering many people still need to gain awareness. What factors play a role in POSBINDU PTM visits in the Tambakharjo is unknown.Method: This research is an observational study with a cross-sectional approach. Systematic sampling was used for 158 people from Tambakharjo aged ≥15 years. Sociodemographic data, history of non-communicable diseases, hypertension knowledge, and POSBINDU PTM visits were collected by interview during November 2023.Result: The research results showed that 22.2% of respondents visited Posbindu-PTM. The multiple logistic regression test showed that the factors that contributed to 99% of POSBINDU PTM visits in Tambakharjo District were ownership of medical equipment (OR=0.332; 95%CI. 0.130-0.845), lack of knowledge about hypertension (OR= 2.300; 95%CI. 0.948-5.579), age ≤45 years (OR=2.53; 95%CI. 1.087-5.393), male gender (OR=6.042; 95%CI=1.677-21.778). The results of this study only describe individual factors. Further studies on psychological factors and the social environment are necessary.
Designing Health Education Model Overcoming Dating Violence for High School Students
Authors: Aprianti Aprianti , Wulandari Respati , Muthoharoh Nor Amalia , Sifai Izzatul Alifah , Azzahra Fatimah
Published: February 2025

Background: The Women's Empowerment and Child Protection Service reported that there were 227 cases of Violence Against Women and Children in Semarang City in 2023, with the most victims being women at 216 people. The highest number of cases of violence occurred at the high school level, with 83 victims. The high number of cases of violence in dating requires prevention efforts. This study aims to design a health education model to address dating violence among high school students in Semarang City.Method: The type of research used is research and development. The P-Process theory is used as material for developing health promotion media. Qualitative and quantitative data sources were obtained in the research and development process. The stages of the research are situation analysis, which is conducted by quantitative research on 118 high school students in Semarang City, and purposive sampling techniques. Quantitative research with focus group discussion was conducted on 10 male and 10 female high school students, and in-depth interviews were conducted with 3 counseling teachers. Quantitative data analysis with the chi-square test, qualitative analysis with thematic content analysis.Result: The average age of respondents was 16 years, with the majority being female. The violence experienced by men was physical violence, while for women, it was psychological and sexual violence. There was a significant relationship between efficacy and self-efficacy responses to overcome violence in dating. For media development, most respondents preferred audiovisual media in the form of films with facilitators being peer educators; the maximum education time was 30 minutes, with materials covering adolescent development, how to overcome violence in dating, healthy dating, and the flow of complaints of violence in dating.
Two-dimensional graph model for epitaxial crystal growth with adatoms
Authors: Cristoferi Riccardo , Fissore Gabriele
Published: February 2025

We consider a model to describe stable configurations in epitaxial growth of crystals in the two-dimensional case, and in the regime of linearized elasticity.
The novelty is that the model also takes into consideration the adatom density on the surface of the film. These are behind the main mechanisms of crystal growth and formation of islands (or quantum dots).
The main result of the paper is the integral representation of the relaxed energy.
Advanced ANN computational procedure for thermal transport prediction in polymer-based ternary radiative Carreau nanofluid with extreme shear rates over bullet surface
Authors: Darvesh Adil , Maiz Fethi Mohamed , Souayeh Basma , Sánchez-Chero Manuel , AL Garalleh Hakim , Santisteban Luis Jaime Collantes , Leonardo Celso Nazario Purihuamán
Published: February 2025

Bullet surface has a significant role in many engineering and industrial sectors, due to its wide fluid-based thermal management systems. The current approach emphasizes heat transfer mechanism in flow of ternary hybrid nanofluid over a bullet shape geometry. The integration of infinite shear rate viscosity-based model of Carreau explored the predictive capabilities of enhanced heat transport in ternary hybrid nanofluid. The purpose of the study is to seek an advanced predictive model that accurately captures the thermal prediction in ternary hybrid nanofluid under varying conditions of shear rate. By utilizing artificial neural networks (ANNs), the aim of this study is to simulate and analyze how these fluids respond to the combined effects of viscous dissipation, non-uniform heat sink source, thermal radiation, and infinite shear rate viscosity when interacting with bullet-shaped geometry. The physical model initially generated a set of partial differential equations, based on assumption in this study, and then this system is converted into ordinary differential equations (ODEs) using similarity transformations. This conversion simplifies the system into a more manageable form. The resulting ODEs are then numerically solved using the bvp4c method. The solutions obtained from this process are compiled into a dataset, which is then used to train through ANN. This neural network is designed to predict advanced solutions. The increase in velocity magnitude increases for stretching ratio and infinite shear rate parameter while it decreases for location parameter and velocity slip parameter. On the other hand, temperature profile decreased with augmentation in the numeric values of radiation parameter and Eckert numbers while it demonstrates the opposite trend for heat generation number and magnetic parameter. The rate of temperature increment is highest in ternary hybrid nanofluids compared to nanofluids and hybrid nanofluids.
Quasi-hereditary algebras with all standard modules being isomorphic to submodules of projective modules
Authors: Fang Ming , Hu Jun
Published: February 2025

Standard modules over quasi-hereditary algebras are by definition certain quotients of projective modules.
In this article, we study when they can be realized as submodules of projective modules, a property enjoyed by Verma modules in the BGG category

𝒪

{\mathcal{O}}

for a finite-dimensional complex semisimple Lie algebra and by quantum Weyl modules over quantized Schur algebras

S
⁢

(
n
,
r
)

{S(n,r)}

with

n
≥
r

{n\geq r}

.
Computation of endo-fixed closures in free-abelian times free groups
Authors: Roy Mallika , Ventura Enric
Published: February 2025

In this paper, we explore the behaviour of the fixed subgroups of endomorphisms of free-abelian times free (FATF) groups. We exhibit an algorithm which, given a finitely generated subgroup

ℋ

{\mathcal{H}}

of a FATF group

𝒢

{\mathcal{G}}

, decides whether

ℋ

{\mathcal{H}}

is the fixed subgroup of some (finite) family of endomorphisms of

𝒢

{\mathcal{G}}

and, in the affirmative case, finds such a family. The algorithm combines both combinatorial and algebraic methods.
Isotypity and direct sum of countably generated modules
Authors: Hasan Ayazul , Rafiquddin Rafiquddin , Hanzla Mohd
Published: February 2025

In the present paper, we consider isotype submodules of those

QTAG

\mathrm{QTAG}

-modules that have countable length and give an in-depth study of their basic
and specific properties either in parallel or in contrast to the direct sum of countably generated modules. In addition, we also examine the

QTAG

\mathrm{QTAG}

-modules whose h-pure submodules are direct sums of countably generated modules.
Analgesic activity of aqueous and methanol fruit pulp extracts of Hyphaene thebaica (Arecaceae) (Linn) mart in mice
Authors: Bomba Tatsinkou Francis Désiré , Fotabong Georlin E. , Wandji Bibiane A. , Mbiantcha Marius , Nembo Erastus N. , Seukep Armel Jackson , Zeuko’o Elisabeth M. , Nguelefack Telesphore B. , Asongalem Emmanuel A.
Published: February 2025

Objectives

Pain affects about one in every five persons and is considered a major global health burden. Hyphaene thebaica (Arecaceae), is a medicinal plant used in Cameroon, fruit pulp are macerated and orally administered in traditional medicine to treat various ailments, including hypertension, pain, and inflammation. This study aimed to evaluate the pain-killing effect of fruit pulp extracts of H. thebaica in mice.

Methods

Aqueous (AEHT) and methanol (MEHT) extracts were prepared from fruit pulp of H. thebaica, followed by a qualitative phytochemical analysis. The extracts were given orally at doses of 100, 200, and 400 mg/kg in acute pain models such as acetic acid, formalin, hotplate, and capsaicin. Control groups included distilled water (negative), and diclofenac, morphine, ruthenium red, diazepam (positive). Naloxone pretreatment was used to assess opioid pathway involvement. Locomotor and sedative effects were evaluated using rota-rod and open-field tests. Acute toxicity was assessed at 2,000 mg/kg.

Results

Phytochemical tests revealed saponins, flavonoids, tannins, and phenols. Both extracts greatly decreased the writhing induced by acetic acid. MEHT inhibited both phases of formalin-induced pain (p<0.01). Both extracts significantly inhibited hotplate-induced nociception (p<0.001), partially reversed by naloxone, except for MEHT. In the capsaicin test, extracts produced a remarkable reduction of paw licking time (p<0.01). No motor coordination alteration or acute toxicity effects were observed.

Conclusions

The findings demonstrated the analgesic activity of AEHT and MEHT, mediated by the stimulation of opioids and blockage of vanilloid receptors pathways.
Experimental investigation on bacterial concrete by using Cantabro loss and UPV
Authors: Syed Riyaz , Pollayi Hemaraju
Published: February 2025

The use of bacterial concrete has become popular as a way to fix fractures in a variety of constructions, including pavements, pipelines, canal linings, bridges, and reinforced concrete buildings. Concrete constructions frequently have cracks that let water and other chemicals in, weakening the structure and compromising reinforcement. Henk Jonkers came up with the idea of bacterial concrete to solve this issue. Concrete cracks were sealed experimentally using calcium lactate and Bacillus subtilis. The bacteria that were chosen were those that could thrive in alkaline conditions. M20 and M40-grade concrete mixes substituted river sand and crushed stone sand for fine aggregate with varying proportions of B. subtilis and calcium lactate. At various curing ages, the study looked at how bacteria affected abrasion resistance. For various mixtures, empirical relationships were proposed between various concrete properties and bacterial content.
Spectrum boundary domination of semiregularities in Banach algebras
Authors: Liu Ying , Kong Yingying , Jiang Lining
Published: February 2025

Let

A

{\mathcal{A}}

be a complex unital Banach algebra and (

R

1

,

R

2

{R}_{1},{R}_{2}

) be a pair of semiregularities in

A

{\mathcal{A}}

. In order to investigate the boundary of spectra in the axiomatic theory of spectrum, this article defines the concept of spectrum boundary domination (SBD) of semiregularities and gives a criterion for a pair (

R

1

,

R

2

{R}_{1},{R}_{2}

) possessing SBD property. Furthermore, the conditions such that

σ

R

1

(

a

)

=

σ

R

2

(

a

)

{\sigma }_{{R}_{1}}\left(a)={\sigma }_{{R}_{2}}\left(a)

are described for

a
∈
A

a\in {\mathcal{A}}

under the assumption that the pair (

R

1

,

R

2

{R}_{1},{R}_{2}

) possesses SBD property. In addition, the transfer of SBD property through a Banach algebra homomorphism is discussed.
Crystal structure of 9-methoxy-4-(2-methoxypyridin-3-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine C19H18N4O2
Authors: Song Mei-Lin , Xie Xian-Rui , Hou Gui-Ge
Published: February 2025

C19H18N4O2, triclinic, P1¯ (no. 2), a = 8.3712(10) Å, b = 9.6699(11) Å, c = 10.5323(12) Å, α = 77.24(1)°, β = 74.576(10)°, γ = 81.126(9)°, V = 797.42(17) Å3, Z = 2, R

gt
(F) = 0.0564, wR

ref
(F
2) = 0.1540, T = 293.0 K.
Crystal structure of (E)-(3-(3-methylthiophen-2-yl)acryloyl)ferrocene, C18H16FeOS
Authors: Wang Yanjiao , Zheng Haoliang , Zhang Keyi , Li Xiaohua , Liu Bin
Published: February 2025

C18H16FeOS, monoclinic, Cc (no. 6), a = 13.4809(7) Å, b = 13.3262(7) Å, c = 9.5652(6) Å, β = 120.604(2)°, V = 1479.02(15) Å3, Z = 4, Rgt
(F) = 0.0364 wRref
(F
2) = 0.0882, T = 170 K.
Animation video frame prediction based on ConvGRU fine-grained synthesis flow
Authors: Duan Xue
Published: February 2025

Due to the complexity and dynamism of animated scenes, frame prediction in animated videos is a challenging task. In order to improve the playback frame rate of animated videos, an innovative convolutional neural network combined with convolutional gated recursive unit method is used to refine the synthesized stream in frame prediction of animated videos. The obtained results indicated that the average prediction accuracy of the proposed model was 99.64%, and the training effect was good. The peak signal-to-noise ratios on the three datasets were 31.26, 36.63, and 22.15 dB, respectively, and the structural similarities were 0.958, 0.886, and 0.813, respectively. The maximum Learned Perceptual Image Patch Similarity of the proposed model was 0.144. This indicates that the model has achieved excellent performance in prediction accuracy and visual quality, which can successfully capture complex dynamics and fine details in animated scenes. The contribution of this study is to provide a technical support for improving the accuracy of frame prediction in animated videos, which will help promote the intelligent development of the animation production field.
Stochastic improved Simpson for solving nonlinear fractional-order systems using product integration rules
Authors: Fareed Aisha F. , Semary Mourad S.
Published: February 2025

This research introduces a novel and robust numerical approach, the stochastic improved Simpson Method, specifically developed to solve Itô and Stratonovich stochastic nonlinear system of differential equations with fractional order. By extending the classical Simpson’s one-third rule with the explicit product integration rectangle rule, the proposed method efficiently handles fractional derivatives of orders between 0 and 1, based on the Caputo derivative. The novelty of this approach lies in its enhanced accuracy and stability in addressing the unique challenges posed by both Itô and Stratonovich systems, outperforming traditional numerical techniques. Rigorous order analysis, conducted with Mathematica 12 software, demonstrates the robustness and precision of the method. Its effectiveness is further validated through four distinct numerical case studies, highlighting its superior performance in solving stochastic nonlinear system of differential equations with fractional order.
Continua and orientations of packing-repacking and unpacking ideational metaphor for knowledge construction
Authors: Zhou Nana
Published: February 2025

This article constructs the multidimensional paradigm to specify the continuum of ideational metaphor by virtue of metaphoricity. Metaphoricity is redefined as a relative term measured by the amount of grammatical metaphor and the rank-shift to delineate the continuum of metaphorization. As an expression is packed and repacked by ideational metaphor, its semantic density increases in implicitness. But its context-dependency declines since ideational metaphor smashes its iconic relation with the reality, which to a certain extent weakens semantic gravity. The orientation towards the nucleus can be instantiated to illustrate the direction of metaphorization. In contrast, as a metaphorical expression is unpacked, its semantic density decreases by releasing the inter-stratal tension between grammar and semantics. Its context-dependency strengthens by rebuilding its iconicity with the reality, which reinforces semantic gravity. An element with the lower nuclearity to Center may be unpacked at the initial stage. This article provides an academic lens for knowledge construction in English teaching and learning.
Emlékkonferencia Győrben Prof. Dr. Rechnitzer János intézetalapító tiszteletére – Beszámoló a konferencia eseményeiről
Authors: Uszkai Andrea
Published: February 2025

2024. november 15-én, a Magyar Tudomány Ünnepe rendezvénysorozat keretében „Éljen a regionális tudomány” címmel emlékkonferenciára került sor a HUN-REN Közgazdaság- és Regionális Tudományi Kutatóközpont Regionális Kutatások Intézete Nyugat-magyarországi Tudományos Osztály szervezésében Győrben, Prof. Dr. Rechnitzer János, intézetalapító, Győr MJV díszpolgára tiszteletére.
Strategic Approaches to Trademark Management at Polish Universities
Authors:   Department of Intellectual Property Law, Faculty of Law, University of Białystok, Poland, Rutkowska-Sowa Magdalena
Published: February 2025

This study examines the role of registered trademarks in university branding, focusing on the Polish context. It explores the initial steps Polish public universities take in trademark management, the regulations they adopt, and the challenges unique to this environment. The topic has not yet been the subject of a comprehensive evaluation within Polish academic doctrine. This research is based on a qualitative analysis of legal frameworks, institutional practices, and documented experiences of Polish universities in the area of trademark management. The potential of trademarks as tools for institutional branding, protection, and revenue generation is often underestimated or overlooked in the strategic planning of Polish higher education institutions. While Polish universities have been developing resources to manage their trademarks effectively - such as building administrative teams and raising awareness about the importance of intellectual property - this potential remains underutilized. Polish universities often rely on public funding or historical prestige, reducing the urgency to actively engage in trademark strategies. This reliance leads to minimal exploration of potential market opportunities, such as partnerships, licensing agreements, or branded merchandise. Without external pressures, Polish institutions seldom capitalize on the competitive advantages that effective trademark management could provide. To unlock the potential of trademark management, Polish universities must adapt to or create market needs by demonstrating their trademarks' value. Strategies include engaging external partners, strengthening alumni networks, and using branding to attract international stakeholders. Institutions like Jagiellonian University provide a model for standardized trademark management, aligning with global trends where universities are both academic and entrepreneurial hubs.
Acute severe hypocalcaemia after initiation of a selective RET-inhibitor in medullary thyroid cancer
Authors: Cheng Leslie , Ghaznavi Syeda Khadijah , Stevens Jessica , Hoy Sonja , Wong Kee Howe , Malik Tass , Newbold Kate , Morganstein Daniel
Published: February 2025

Medullary thyroid cancer (MTC) is a rare subtype of thyroid cancer originating from parafollicular C-cells of the thyroid. Tyrosine kinase inhibitors are used to treat patients with advanced MTC. Selpercatinib is a highly selective RET inhibitor used in the treatment of advanced RET-mutated MTC, having shown higher potency and fewer side effects compared to multikinase inhibitors in clinical trials. As a relatively new drug, its toxicity profile continues to be characterised. This report describes a case of severe acute hypocalcaemia in a 64-year-old male with advanced MTC treated with selpercatinib. The patient, who had stable hypoparathyroidism, experienced acute hypocalcaemia (corrected calcium 1.4 mmol/L) 2 weeks after initiating selpercatinib, requiring hospitalisation for calcium supplementation and monitoring. Selpercatinib was temporarily withheld and later reintroduced at a lower dose, successfully preventing recurrence of hypocalcaemia. Investigations excluded other common or important causes of hypocalcaemia, which led us to conclude that this could be a drug-related adverse event. This case highlights the need for careful monitoring of electrolyte disturbances in patients on selpercatinib, particularly those with pre-existing hypoparathyroidism. Although rare, the development of hypocalcaemia with RET inhibitors may necessitate dose interruptions and adjustments. Our experience has also illustrated that re-challenge with selpercatinib is feasible with appropriate management strategies.
Real-world outcomes of lenvatinib therapy for advanced neuroendocrine neoplasms
Authors: Solar Vasconcelos Joao Paulo , Nunez Rodriguez Jose Eduardo , Zaidi Ali , Krishnan Tharani , Jafari Helia , Gill Sharlene , Tan Ann , Le Dan , Chan Theresa , Yu Simon , McGhie John Paul , Lim Howard , Singh Simron , Loree Jonathan M
Published: February 2025

Advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) constitute a heterogeneous group of incurable cancers. Lenvatinib is an oral multiple kinase inhibitor that showed activity in grade 1/2 GEP-NENs in the phase II TALENT trial, but a confirmatory phase III study has yet to be conducted. To investigate the real-world use of lenvatinib in treating patients with advanced GEP-NENs, we retrospectively analyzed a cohort of adults with unresectable neuroendocrine neoplasms (NENs) from two academic centers in Canada who received palliative treatment with lenvatinib. Progression-free survival (PFS), overall survival (OS) and the treating clinician assessment of best therapeutic response were analyzed in the entire cohort and in the subgroup of patients with GEP-NENs that would have been eligible for the TALENT trial. Overall, 33 patients, with mostly G1/G2 (78.8%) metastatic NENs, received lenvatinib. The pancreas was the most common primary site (n = 16, 48.5%), followed by the small bowel (n = 12, 36.4%). The median number of prior lines of systemic therapy was 2 (range 1–5). The median initial, maximal and minimal doses (mg) were 12 (range 4–24), 12 (range 8–24) and 8 (range 4–24), respectively. The median PFS was 11.9 months (95% CI, 9.5–NA), and the median OS was 17.5 months (95% CI, 12.7–NA), with disease burden reduction seen in 21.9% (95% CI, 11.0–38.7) and 87.5% (95% CI, 71.9–95.3) of patients achieving disease control. The most frequent side effects reported were hypertension (60.6%), fatigue (39.4%), hypothyroidism (21.2%) and diarrhea (18.2%). This real-world cohort demonstrates encouraging evidence of lenvatinib activity in metastatic NENs, even when used at lower doses than previously studied in NENs.
Chronological levels of As, Pd, V, and Sr in 356-year-old Pinus nigra annual rings in Northern Türkiye
Authors: Koç İsmail
Published: February 2025

The accumulation and allocation of heavy metals—arsenic (As), strontium (Sr), palladium (Pd), and vanadium (V)—were measured in Pinus nigra wood over more than three centuries. Contrary to expectations, the results did not show a correlation between increasing air pollution in recent decades and the concentrations of these metals in annual rings. Thus, P. nigra wood appears unsuitable as a biomonitor for tracking long-term heavy metal pollution in air. However, metals deposited in specific annual rings remained restricted within those rings, supporting the hypothesis of limited radial migration over time. The study specified P. nigra as a promising candidate for phytoremediation due to its capacity to accumulate high concentrations of As, Sr, Pd, and V. Additionally, these metals exhibited robust positive correlations with other toxic elements (tin, antimony, niobium, silver, thallium, selenium, and lead), suggesting that P. nigra could serve as an indicator of regions with multiple heavy metal pollutants. These findings highlight the complexity of metal uptake and allocation processes in trees and underscore the need for further research in controlled environments to clarify mechanisms of metal transfer and toxicity. Despite its limitations relative to its usage as a biomonitor, P. nigra demonstrated potential for mitigating heavy metal contamination in polluted environments.
The effect of alkali lignin on laccase activity and mycelial biomass of Flammulina velutipes: Alkali lignin on laccase activity and mycelial biomass
Authors: Han Mei-Ling , Zhao Yi-Lin , Liu Tian-Yu , Bian Lu-Sen , Li Zi-Han , Li Ming-Xue , Li Jia , Yang Xiao-Qi , An Qi
Published: February 2025

The effect of alkali lignin on laccase activity and mycelial biomass of Flammulina velutipes was investigated at different fermentation temperatures. The secretion of laccase by F. velutipes has certain specificity. Under most fermentation medium conditions, no laccase activity of F. velutipes CCMSSC 00103 was detected, but laccase activity of F. velutipes FL 19 could be detected. Among the three strains of F. velutipes, the laccase secretion capacity of F. velutipes FL 19 was clearly higher than that of F. velutipes CCMSSC 05331 and F. velutipes CCMSSC 00103. Maximum laccase activity with the value of 73.42 ± 4.74 U/L was secreted by F. velutipes FL 19 in fermentation medium with alkali lignin, KH2PO4, Vitamin B1, and glucose, and appeared on the 2nd day. The presence of alkali lignin was useful for improving laccase activity secreted by F. velutipes. The effect of alkali lignin on improving laccase activity exceeded that of Populus beijingensis. F. velutipes was more suitable for secreting laccase at 26 °C because the maximum laccase activity at 26 °C (73.42 ± 4.74 U/L) was higher than that measured at 33 °C (70.71 ± 6.89 U/L). The results can be useful for selecting suitable medium and temperature of F. velutipes strains to produce low-cost laccase.
Preparation of activated carbons from hemicellulose pre-extraction residue of eucalyptus heartwood and sapwood and their application in toluene adsorption
Authors: Huang Xixiang , Zhao Yuanyuan , Wang Zhiwei , Wang Yanhong , Zhou Yun , Cheng Hao , Li Penghui , Wu Shubin
Published: February 2025

Pre-extraction of hemicellulose from eucalyptus heartwood and sapwood was conducted using the method of KOH extraction. Activated carbons (ACs) with high toluene adsorption capacity were prepared by using KOH as activator and hemicellulose-pre-extracted residue (HPR) as AC precursor. The findings indicated that the pore structure of the ACs could be regulated by adjusting the carbonization temperature. Using the HPR of eucalyptus heartwood as raw material, the activated carbon carbonized at 400 °C exhibited the highest BET surface area (3699 m2·g-1) and pore volume (1.90 cm3·g-1). The adsorption capacity of AC for toluene reached 816 mg·g-1. The results showed that the adsorption capacity of toluene was associated with the micropores (< 2 nm) in the AC. Optimizing the carbonization temperature could enhance the proportion of micropores, thereby significantly enhancing the activated carbon’s adsorption capacity for toluene.
ІДЕОНІМОСФЕРА ЕПІСТОЛЯРНОГО ТЕКСТУ
Authors: Попова І.
Published: February 2025

Постановка проблеми. Епістолярна спадщина є вагомим складником усього культурного й духовного надбання українського народу, а її мовний вияв активно вивчають. Серед традиційних жанрових різновидів епістолярного жанру важливе місце посідають листи як особливий вид комунікативної діяльності. У 1-й книзі «Листи до Олеся Гончара» (2016) опубліковано 895 текстів-листів українських та зарубіжних майстрів слова до видатного українського письменника. Серед різноманіття і багатогранності мовних засобів організації листових текстів особливу вагу мають пропріативи, без яких важко, а то й неможливо, характеристично й максимально повно відтворити факт приватного звернення-сповіді однієї особи до іншої. Органічним компонентом серед онімів текстів-листів до Олеся Гончара є ідеоніми – власні назви, що на противагу прагмонімам, пов’язаним з номінацією об’єктів матеріальної культури, позначають витвори людської культури, мистецтва або науки, які мають духовну та інтелектуальну цінність.
Метою статті є дослідження розгалуженої ідеонімосфери приватної кореспонденції численних авторів до Олеся Гончара.
Методи дослідження. Методологійною основою дослідження є положення про системність мовних і мовленнєвих явищ, що передбачає використання таких основних методів лінгвістичного аналізу й окремих їхніх прийомів, як описовий, спостереження, систематизація і узагальнення, контекстуально-інтерпретаційний, що дає змогу виявити особливості функціонування ідеонімів в епістолярному тексті.
Висновки і перспективи. Серед різноманіття онімного простору 1-ї книги «Листи до Олеся Гончара» окремішнє місце посідають ідеоніми, що об’єднані в певну систему тематичних груп за типом денотованого об’єкта, серед яких описані бібліоніми, артіоніми, поетоніми з відповідними різновидами, а також гемероніми, геортоніми та хрононіми. Структурно ідеоніми в аналізованому матеріалі представлені як ідеоніми-словоформи, словосполучення, словоз’єднання та фрази, що загалом характерні для будь-якого іншого різновиду пропріативів в епістолярному тексті.
Перспективою подальших досліджень може бути опис різновидів онімних назв та їхньої структури в 2-й книзі «Листи до Олеся Гончара» в контексті і з огляду на час їхнього написання.
O O palácio de Palermo, Versailles del Plata
Authors: Lacoste Pablo Alberto , Skewes Juan Carlos
Published: February 2025

En el marco de las guerras civiles y exteriores que enfrentó la Confederación Argentina en las décadas de 1830 y 1840, se examina la movilización y visibilización del patrimonio cultural y agroalimentario mestizo que promovió Juan Manuel de Rosas como estrategia de poder blando. Se destaca el papel del palacio de Palermo como espacio de cohesión y unidad nacional, junto con la puesta en valor de arquitectura, utensilios, alimentos y bebidas patrimoniales.
Determination of soil particle size distribution using computer analysis of microscopic images
Authors:   University of Agriculture in Krakow, Głąb Tomasz , Knaga Jarosław ,   University of Agriculture in Krakow, Zaleski Tomasz ,   University of Agriculture in Krakow, Dziwisz Paweł ,   Aumatic Ltd, Gluza Jan ,   Aumatic Ltd, Glanas Dariusz ,   Aumatic Ltd
Published: February 2025

The project aims to develop a prototype device for determining the texture of soils and mineral deposits. The innovation of the designed solution consists in a significant reduction in the time of composition analysis with the possibility of any division into granulometric groups and the complete automation of the measurement from the moment the sample is introduced into the apparatus until the result is obtained. As part of the project, industrial research and experimental development are planned to be divided into the following stages:

1. Development of the measuring system.

2. Development of the structure and construction of device prototypes.

3. Development of the construction of the measuring system

4. Development of a mathematical model for processing data from the measuring system.

5. Preparation of software for device control and data recording.

6. Making the final prototype of the device.

7. Test tests of the final version of the device.

The research will be conducted by a research consortium consisting of the project leader, i.e. Aumatic sp. z o.o. and the University of Agriculture in Krakow. The developed product will be intended for sale both on the domestic market and for export. Due to the number of entities potentially interested in the apparatus and the financial possibilities of potential recipients, the largest market should be developed countries (e.g. EU countries, USA, Canada, etc.). The main target groups of clients were:

1. Scientific institutions (universities, research institutes).

2. Institutions and enterprises performing analyzes for the needs of precision farming.

3. Chemical and Agricultural Stations.

4. Ceramic clay mining plants.

5. Manufacturers of ceramic products.

6. Laboratories conducting geotechnical tests for the needs of construction.

7. Laboratories carrying out environmental tests in the field of soil quality.

8. Provincial Inspectorates for Environmental Protection, Regional Directorates for Environmental Protection
Zanne Domoney-Lyttle: 'The Bible and Comics'; Assaf Gamzou and Ken Koltun-Fromm, eds.: 'Comics and Sacred Texts'
Authors: Dillon Amanda
Published: February 2025

Review Essay
Zanne Domoney-Lyttle: The Bible and Comics: Women, Power and Representation in Graphic Narratives. Scriptural Traces: Critical Perspectives on the Reception and Influence of the Bible. London: Bloomsbury T&T Clark (2024)
Assaf Gamzou and Ken Koltun-Fromm, eds.: Comics and Sacred Texts: Reimagining Religion and Graphic Narratives. Oxford, MS: University Press of Mississippi (2018)