bluuebunny/crossref_metadata_2025 huggingface dataset:
Is Model Accuracy Enough? A Field Evaluation of a Machine Learning Model to Catch Bogus Firms
Authors: Barwahwala Taha , Mahajan Aprajit , Mittal Shekhar , Reich Ofir
Published: July 2024

We investigate the use of a machine learning (ML) algorithm to identify fraudulent non-existent firms that are used for tax evasion. Using a rich dataset of tax returns in an Indian state over several years, we train an ML-based model to predict fraudulent firms. We then use the model predictions to carry out field inspections of firms identified as suspicious by the ML tool. We find that the ML model is accurate in both simulated and field settings in identifying non-existent firms. Withholding a randomly selected group of firms from inspection, we estimate the causal impact of ML-driven inspections. Despite the strong predictive performance, our model-driven inspections do not yield a significant increase in enforcement as evidenced by the cancellation of fraudulent firm registrations and tax recovery. We provide two explanations for this discrepancy based on a close analysis of the tax department’s operating protocols: overfitting to proxy-labels and institutional friction in integrating the model into existing administrative systems. Our study serves as a cautionary tale for the application of machine learning in public policy contexts and of relying solely on test-set performance as an effectiveness indicator. Field evaluations are critical in assessing the real-world impact of predictive models.
Theory and Observation of Winds from Star-Forming Galaxies
Authors: Thompson Todd A. , Heckman Timothy M.
Published: July 2024

Galactic winds shape the stellar, gas, and metal content of galaxies. To quantify their impact, we must understand their physics. We review potential wind-driving mechanisms and observed wind properties, with a focus on the warm ionized and hot X-ray-emitting gas. Energy and momentum injection by supernovae (SNe), cosmic rays, radiation pressure, and magnetic fields are considered in the light of observations:
▪Emission and absorption line measurements of cool/warm gas provide our best physical diagnostics of galactic outflows.▪The critical unsolved problem is how to accelerate cool gas to the high velocities observed. Although conclusive evidence for no one mechanism exists, the momentum, energy, and mass-loading budgets observed compare well with theory.▪A model in which star formation provides a force ∼L/c, where L is the bolometric luminosity, and cool gas is pushed out of the galaxy's gravitational potential, compares well with available data. The wind power is ∼0.1 of that provided by SNe.▪The very hot X-ray-emitting phase may be a (or the) prime mover. Momentum and energy exchange between the hot and cooler phases is critical to the gas dynamics.▪Gaps in our observational knowledge include the hot gas kinematics and the size and structure of the outflows probed with UV absorption lines.
Simulations are needed to more fully understand mixing, cloud–radiation, cloud–cosmic ray, andcloud–hot wind interactions, the collective effects of star clusters, and both distributed andclustered SNe. Observational works should seek secondary correlations in the wind data thatprovide evidence for specific mechanisms and compare spectroscopy with the column density–velocity results from theory.
Toward a Natural History of Microbial Life
Authors: Magnabosco Cara , Husain Fatima , Paoletti Madeline M. , Parsons Chris , Payette Jack G. , Schwartz Sarah L. , Tamre Erik , Fournier Gregory P.
Published: July 2024

For most of Earth's history life was microbial, with archaeal and bacterial cells mediating biogeochemical cycles through their metabolisms and ecologies. This diversity was sufficient to maintain a habitable planet across dramatic environmental transitions during the Archean and Proterozoic Eons. However, our knowledge of the first 3 billion years of the biosphere pales in comparison to the rich narrative of complex life documented through the Phanerozoic geological record. In this review, we attempt to lay out a microbial natural history framework that highlights recent and ongoing research unifying microbiology, geochemistry, and traditional organismal evolutionary biology, and we propose six broadly applicable principles to aid in these endeavors. In this way, the evolutionary history of microbial life—once considered only a prelude to the much more storied history of complex metazoan life in the Phanerozoic—is finally coming into its own.
▪The outlines of microbial natural history are now starting to appear through the integration of genomic and geological records.▪Microorganisms drive Earth's biogeochemical cycles, and their natural history reflects a coevolution with the planet.▪Past environmental changes have induced microbial biotic transitions, marked by extinction, taxonomic shifts, and new metabolisms and ecologies.▪Microbial evolution can benefit from a historical perspective of processes and successions as established by macropaleontology.
Metabolic and Morphological Aspects of Adaptation of Alkaliphilic Bacillus aequororis 5‐DB and Alkali‐Tolerant Bacillus subtilis ATCC 6633 to Changes in pH and Mineralization
Authors: Maksimova Yuliya , Eliseeva Ann , Maksimov Aleksandr
Published: July 2024

The goal of the study is to evaluate metabolic and morphological changes of the facultative alkaliphile Bacillus aequororis 5‐DB and the weakly alkali‐resistant B. subtilis ATCC 6633 in a wide pH range and at different NaCl concentrations. The alkaliphile B. aequororis 5‐DB is shown to have a broader general resistance to adverse factors (wide pH range, 50 g/L NaCl) than a weakly alkali‐tolerant strain of the same genus. This alkaliphile is also shown to have a significantly greater resistance not only to high pH but also to low pH in comparison with B. subtilis ATCC 6633. The resistance of B. aequororis 5‐DB to low pH was expressed in higher metabolic activity, maintenance of ΔpH, and no significant cell damage. The selected set of methods (reduction of resazurin to resorufin by cell dehydrogenases, bioluminescent method for determining ATP, AFM, and measurement of intracellular pH) allows us to adequately assess the ability of microbial cells to withstand harsh environmental factors. Nonspecific resistance of B. aequororis 5‐DB was proven using a complex of selected methods. Tolerance to a wide range of pH and high salt concentrations may be useful for biotechnological applications of the strain.
Enhancing Image Cryptography Performance with Block Left Rotation Operations
Authors: Al-Batah Mohammad Subhi , Alzboon Mowafaq Salem , Alzyoud Mazen , Al-Shanableh Najah
Published: July 2024

In today’s interconnected world, the transmission of both lengthy and concise text messages is ubiquitous across diverse communication platforms. With the proliferation of sensitive and specialized information being exchanged, safeguarding these messages from potential threats such as intruders, abusers, and data hackers becomes imperative. This study introduces an innovative approach aimed at streamlining data protection procedures while concurrently thwarting hacking attempts. At the core of this method lies the utilization of a sophisticated variable content private key designed to facilitate ease of alteration without compromising the integrity of encryption and decryption operations. The pivotal aspect involves leveraging a covert color image to generate this private key, mandating both the sender and receiver to securely retain this image. By employing a selected color image, the private key can seamlessly adapt to match the length of the confidential message. To fortify the level of security, the message is recommended to be segmented into blocks of predetermined sizes, with the sender and receiver jointly establishing these parameters. Subsequently, the bytes within each block are consolidated into a singular vector, which undergoes a left rotation by a predetermined number of bits as specified by the communicating parties. The proposed methodology is empirically validated through the implementation of various color images and text messages. Comparative analyses against existing methods underscore the efficacy and robustness of the proposed approach, substantiating its significant advancements in data protection paradigms.
Outcomes and Its Associated Factors among Patients with Abdominal Trauma Requiring Laparotomy at Asella Referral and Teaching Hospital, South Central Ethiopia: A Retrospective Cross‐Sectional Study
Authors: Shenkutie Wegene Tadesse , Kaso Taha , Kaso Abdene Weya , Agero Gebi
Published: July 2024

Trauma is a serious public health problem, and abdominal injuries are among the leading causes of hospitalization after trauma. Therefore, this study aimed to determine the outcome of abdominal trauma and its predictors in patients who underwent laparotomy at Asella Referral and Teaching Hospital (ARTH), South Central Ethiopia. We conducted a retrospective institutional based cross‐sectional study of patients who underwent laparotomy for abdominal trauma at ARTH from October 1, 2015, to September 30, 2020. Bivariate and multivariate logistic regressions were used to determine associations between independent factors and mortality due to abdominal trauma, and a P value of <0.05 indicated statistical significance. Out of 139 patients, 110 (79.1%) were males and 88 (63.3%) aged <30 years old, with a mean age of 29 ± 15.73 years. The most common mechanism of injury was penetrating trauma, which accounted for 94 (67.6%) patients. The mortality rate was 21 (15.1%). Factors such as blunt mechanism of injury (95% CI: AOR: 3.36, 1.24–9.09), SBP < 90 mmHg at presentation (95% CI: AOR = 9.37, 3.28–26.80), time >6 hours from trauma to admission (95% CI: AOR: 5.44, 1.78–16.63), unstable intraoperative patient condition (95% CI: AOR = 8.82, 3.05–25.52), and patients who need blood transfusion (95% CI: AOR: 6.63, 1.92–22.91) were significantly associated with mortality. The mortality rate of abdominal trauma patients who underwent laparotomy was high. Therefore, healthcare providers should provide priority for traumatic patients as prolonged waiting time to get healthcare results in poor outcomes for the patients.
Tension Characteristics Analysis of Scraper Chain of Heavy‐Duty Scraper Conveyor with Time‐Varying Loads
Authors: Li Shuai , Zhu Zhencai , Lu Hao , Xue Yujun
Published: July 2024

With the intensification and large scale of coal mining, scraper conveyors are developing towards high power, large volume, long haul distance, and high reliability. It is more and more important to obtain the dynamic tension of the scraper chain with time‐varying loads. The purpose of this paper is to obtain the dynamic tension of scraper chains of the scraper conveyor with time‐varying loads. First, according to the structural characteristics and working environment of the scraper conveyor and the polygon effect of the sprocket, the scraper conveyor dynamic model under the action of the time‐varying loads is established by the finite unit method. Second, the load variation rule of the bearing section is explored when the scraper conveyor and shearer work together. Furthermore, the element resistance of each discrete element, the stiffness coefficient of the scraper chain, and the influence of polygonal effect of sprocket wheel are analyzed. And then, the dynamic tension of the scraper chain is obtained by the Hilber–Hughes–Taylor (HHT) method. Finally, the validity of the scraper conveyor dynamic model is verified by the example analysis and field measurement experiment. Due to the influence of heavy starting, the maximum tension of the scraper chain during the starting process is 751.6 kN, which is 12.25% higher than the tension with smooth running (669.6 kN). During the startup stage, significant impacts occur on both motors and scraper chains which may lead to damage. To protect these components effectively, control strategies such as “soft start” or no‐load start hold crucial engineering significance in achieving reliable operation of the scraper conveyor. The obtained results can provide a theoretical basis for the reliability evaluation and parameter optimization of the scraper conveyor.
Metabolomics Combined with Network Pharmacology to Explore the Active Components and Mechanism of Tetrastigma planicaule (Hook.) Gagnep. in the Treatment of Rheumatoid Arthritis
Authors: Qiu Qin , Qin Chunping , Li Pengfei , Meng Xueyan , Mo Huiqing , Huang Chunying , Wei Jiangcun , Zhen Hanshen , He Yun , Ouyang Di , Huang Xiaodong
Published: July 2024

Context. Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease. It is characterized by persistent joint damage. Traditional Chinese medicine (TCM) has demonstrated notable efficacy in managing RA. Prior investigations have indicated that the ethyl acetate extract of Tetrastigma planicaule (Hook.) Gagnep. (TP) possesses substantial anti‐inflammatory properties, suggesting the potential for screening TCM drugs with antirheumatoid arthritis attributes. However, the precise mechanism underlying its pharmacological effects and material basis remains unclear, impeding the advancement of TCM innovation. Objective. This study is to elucidate the active components and mechanism of TP in the treatment of RA. Materials and Methods. A rat model of collagen‐induced arthritis (CIA) was established for conducting pharmacological experiments to assess the effectiveness of ethyl acetate extract from TP in treating RA. In addition, nuclear magnetic resonance (NMR) metabolomics technology was employed to identify potential endogenous biomarkers for further metabolic pathway analysis. The active compounds and key targets were investigated using ultraperformance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (UPLC‐Q‐TOF‐MS/MS) technology in combination with network pharmacology. Moreover, common gene targets discovered by metabolomics and network pharmacology were validated by molecular docking with the relevant active components. Result. 12 endogenous biomarkers were screened by 1H‐NMR metabolomics technology. The metabolite pathways are primarily implicated in lipid metabolism and amino acid metabolism. 49 compounds were identified in TP, of which 10 were considered active ingredients through network pharmacological analysis. In a comprehensive analysis, it was found that TP exhibited a strong association with the PLA2G4A and lipid metabolite pathways in RA. Molecular docking studies further demonstrated a high affinity between the active compounds of TP and PLA2G4A. Discussion and Conclusions. TP may play a therapeutic role in RA by regulating PLA2G4A and participating in back‐regulating the glycerophospholipid metabolic pathway. The study elucidated the multicomponent, multitarget, and multipathway mechanism of TP in the treatment of RA, laying the groundwork for a deeper understanding of its therapeutic mechanisms.
Figure 1 from A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170)
Authors: Maldonado Edward , Rathmell W. Kimryn , Shapiro Geoffrey I. , Takebe Naoko , Rodon Jordi , Mahalingam Devalingam , Trikalinos Nikolaos A. , Kalebasty Arash R. , Parikh Mamta , Boerner Scott A. , Balido Celene , Krings Gregor , Burns Timothy F. , Bergsland Emily K. , Munster Pamela N. , Ashworth Alan , LoRusso Patricia , Aggarwal Rahul R.
Published: July 2024

Patient disposition.
Data from A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170)
Authors: Maldonado Edward , Rathmell W. Kimryn , Shapiro Geoffrey I. , Takebe Naoko , Rodon Jordi , Mahalingam Devalingam , Trikalinos Nikolaos A. , Kalebasty Arash R. , Parikh Mamta , Boerner Scott A. , Balido Celene , Krings Gregor , Burns Timothy F. , Bergsland Emily K. , Munster Pamela N. , Ashworth Alan , LoRusso Patricia , Aggarwal Rahul R.
Published: July 2024

Abstract
We sought to evaluate the efficacy of WEE1 inhibitor adavosertib in patients with solid tumor malignancies (cohort A) and clear cell renal cell carcinoma (ccRCC; cohort B). NCT03284385 was a parallel cohort, Simon two-stage, phase II study of adavosertib (300 mg QDAY by mouth on days 1–5 and 8–12 of each 21-day cycle) in patients with solid tumor malignancies harboring a pathogenic SETD2 mutation. The primary endpoint was the objective response rate. Correlative assays evaluated the loss of H3K36me3 by IHC, a downstream consequence of SETD2 loss, in archival tumor tissue. Eighteen patients were enrolled (9/cohort). The median age was 60 years (range 45–74). The median duration of treatment was 1.28 months (range 0–24+). No objective responses were observed in either cohort; accrual was halted following stage 1. Minor tumor regressions were observed in 4/18 (22%) evaluable patients. Stable disease (SD) was the best overall response in 10/18 (56%) patients, including three patients with SD > 4 months. One patient with ccRCC remains on treatment for >24 months. The most common adverse events of any grade were nausea (59%), anemia (41%), diarrhea (41%), and neutropenia (41%). Nine patients (50%) experienced a Grade ≥3 adverse event. Of eight evaluable archival tissue samples, six (75%) had a loss of H3K36me3 by IHC. Adavosertib failed to exhibit objective responses in SETD2-altered ccRCC and other solid tumor malignancies although prolonged SD was observed in a subset of patients. Combination approaches may yield greater depth of tumor response.
Significance:
WEE1 inhibition with adavosertib monotherapy demonstrated limited clinical activity in patients with SETD2-altered solid tumors despite compelling preclinical data indicating a synthetic lethal effect, which did not translate into robust tumor regression. Loss of the H3K36me3 trimethylation mark caused by SETD2-deficiency was confirmed in the majority of evaluable tumors. A subset of patients derived clinical benefit as manifested by minor tumor regressions and prolonged SD.
Deficits of Facial Emotion Recognition in Elderly Individuals with Mild Cognitive Impairment
Authors: Ju Eun-Yoo , Kim Chae Yoon , Choi Baek-Yong , Ryoo Seung-Woo , Min Jin-Young , Min Kyoung-Bok
Published: July 2024

Introduction: The study of facial emotion recognition is under-explored in subjects with mild cognitive impairment (MCI). We investigated whether deficits in facial emotion recognition are present in patients with MCI. We also analyzed the relationship between facial emotion recognition and different domains of cognitive function. Methods: This study included 300 participants aged 60 years or older with cognitive decline. We evaluated 181 MCI and 119 non-MCI subjects using the Seoul Neuropsychological Screening Battery-Core (SNSB-C) and facial emotion recognition task using six facial expressions (anger, disgust, fear, happiness, sadness and surprise). A Generalized Linear Model (GLM) was used to assess the association between cognitive performance and accuracy of facial emotion recognition and to compare facial emotion recognition in the MCI group based on the impairment of five different domains of cognitive function. The model was adjusted for age, sex, years of education, and depressive symptoms. Results: Patients with MCI had a lower score for accurately recognizing total facial emotion (0.48 vs. 0.53; ρ = 0.0003) and surprise (0.73 vs. 0.81; ρ = 0.0215) when compared to cognitively healthy subjects. We also discovered that frontal/executive function domain (Digit Symbol Coding [DSC, 0.38 vs. 0.49; p < 0.0001], Controlled Oral Word Association Test [COWAT, 0.42 vs. 0.49; p = 0.0001], Korean-Trail Making Test [K-TMT, 0.37 vs. 0.48; p = 0.0073], Korean-Color Word Stroop Test [K-CWST, 0.43 vs. 0.49; p = 0.0219]) and language domain (Korean-Boston Naming Test [S-K-BNT, 0.46 vs. 0.47; p = 0.003]) were statistically associated with the deficits of facial emotion recognition in patients with MCI. Conclusion: We observed a significant association between deficits in facial emotion recognition and cognitive impairment in elderly individuals.
Eye Size Does Not Change with Artificial Selection on Relative Telencephalon Size in Guppies (Poecilia reticulata)
Authors: Boussard Annika , Garate-Olaizola Maddi , Fong Stephanie , Kolm Niclas
Published: July 2024

Introduction: Variation in eye size is sometimes closely associated with brain morphology. Visual information, detected by the retina, is transferred to the optic tectum to coordinate eye and body movements towards stimuli and thereafter distributed into other brain regions for further processing. The telencephalon is an important visual processing region in many vertebrate species and a highly developed region in visually dependent species. Yet, the existence of a coevolutionary relationship between telencephalon size and eye size remains relatively unknown. Methods: Here, we use male and female guppies artificially selected for small- and large-relative-telencephalon-size to test if artificial selection on telencephalon size results in changes in eye size. In addition, we performed an optomotor test as a proxy for visual acuity. Results: We found no evidence that eye size changes with artificial selection on telencephalon size. Eye size was similar in both absolute and relative terms between the two selection regimes but was larger in females. This is most likely because of the larger body size in females, but it could also reflect their greater need for visual capacity due to sex-specific differences in foraging and mating behaviour. Although the optomotor response was stronger in guppies with a larger telencephalon, we found no evidence for differences in visual acuity between the selection regimes. Conclusion: Our study suggests that eye size and visual perception in guppies do not change rapidly with strong artificial selection on telencephalon size.
Mechanistic Insights From Trials of Atrial Fibrillation Ablation: Charting a Course for the Future
Authors: Goldberger Jeffrey J. , Mitrani Raul D. , Zaatari Ghaith , Narayan Sanjiv M.
Published: July 2024

Success rates for catheter ablation of atrial fibrillation (AF), particularly persistent AF, remain suboptimal. Pulmonary vein isolation has been the cornerstone for catheter ablation of AF for over a decade. While successful for most patients, pulmonary vein isolation alone is still insufficient for a substantial minority. Frustratingly, multiple clinical trials testing a diverse array of additional ablation approaches have led to mixed results, with no current strategy that improves AF outcomes beyond pulmonary vein isolation in all patients. Nevertheless, this large collection of data could be used to extract important insights regarding AF mechanisms and the diversity of the AF syndrome. Mechanistically, the general model for arrhythmogenesis prompts the need for tools to individually assess triggers, drivers, and substrates in individual patients. A key goal is to identify those who will not respond to pulmonary vein isolation, with novel approaches to phenotyping that may include mapping to identify alternative drivers or critical substrates. This, in turn, can allow for the implementation of phenotype-based, targeted approaches that may categorize patients into groups who would or would not be likely to respond to catheter ablation, pharmacological therapy, and risk factor modification programs. One major goal is to predict individuals in whom additional empirical ablation, while feasible, may be futile or lead to atrial scarring or proarrhythmia. This work attempts to integrate key lessons from successful and failed trials of catheter ablation, as well as models of AF, to suggest future paradigms for AF treatment.
Feasibility, Accuracy, and Reproducibility of Aortic Valve Sizing for Transcatheter Aortic Valve Implantation Using Virtual Reality
Authors: Kanschik Dominika , Haschemi Jafer , Heidari Houtan , Klein Kathrin , Afzal Shazia , Maier Oliver , Piayda Kerstin , Binneboesssel Stephan , Oezaslan Goeksen , Bruno Raphael R. , Antoch Gerald , Lichtenberg Artur , Fleissner Felix , Scherner Maximillian , Kelm Malte , Zeus Tobias , Jung Christian
Published: July 2024

Background

Detailed visualization and precise measurements of aortic valve dimensions are critical for the success of transcatheter aortic valve implantation and for the prevention of complications. Currently, multislice computed tomography is the gold standard for assessment of the aortic annulus and surrounding structures to determine the prosthesis size. New technologies such as virtual reality (VR) not only enable 3‐dimensional (3D) visualization with the potential to improve understanding of anatomy and pathology but also allow measurements in 3D. This study aims to investigate the feasibility, accuracy, and reproducibility of VR for the visualization of the aortic valve, the surrounding structures, and its role in preprocedural sizing for transcatheter aortic valve implantation.

Methods and Results

Based on the preprocedural multislice computed tomography data, 3mensio measurements and 3D visualizations and measurements using VR software were performed retrospectively on 60 consecutive patients who underwent transcatheter aortic valve implantation at our heart center. There were no significant differences but strong correlations between the VR measurements compared with those performed with the 3mensio software. Furthermore, excellent or good intra‐ and interobserver reliability could be demonstrated for all values. In a structured questionnaire, users reported that VR simplified anatomical understanding, improved 3D comprehension of adjacent structures, and was associated with very good self‐perceived depth perception.

Conclusions

The use of VR for preprocedural transcatheter aortic valve implantation sizing is feasible and has precise and reproducible measurements. In addition, 3D visualization improves anatomical understanding and orientation. To evaluate the potential benefits of 3D visualization for planning further cardiovascular interventions, research in this field is needed.
Intrinsic functional and structural network organization in the macaque insula
Authors: Charbonneau Joey A. , Raven Erika P. , Katsumi Yuta , Santistevan Anthony C. , Taylor Christopher , Bliss-Moreau Eliza
Published: July 2024

In recent decades, in vivo magnetic resonance imaging (MRI) studies have provided previously inaccessible insights into the structure and function of healthy and pathological human brains in the laboratory and the clinic. However, the correlational nature of this work and relatively low resolution mean that ground truth neuroanatomical studies and causal manipulations of neural circuitry must still occur in animal models offering greater tractability and higher resolution, rendering a scale and species gap in translation. Here, we bridge this gap with a detailed, multimodal investigation of the macaque insula in vivo. Using both functional and diffusion MRI—tools available for use in humans—we demonstrate a neural architecture in the macaque insula with clear correspondence to prior in vivo MRI findings in humans and postmortem cytoarchitectural and tract-tracing studies in monkeys. Results converged across analysis methods and imaging modalities, supporting the translational potential of the macaque model.
The development of a research intelligence tool for rare disease research in the Netherlands
Authors: Iping Rik , Nederveen Ilse , Ranjbar-Sahraei Bijan , Azarbonyad Hosein , Dumoulin Max , Tsatsaronis Georgios , Mathijssen Irene M. J.
Published: July 2024

This article describes the process of the development of a research intelligence tool to analyze rare disease research in the Netherlands. To the best of our knowledge, this is the first tool that can surface and organize scientific output on rare diseases using established annotation and natural language processing mechanisms. We focus on the track leading up to the development, including strategic motivation and user needs, of a proof-of-concept tool, upscaling the idea to a national collaboration project, the development of the final tool and a usability evaluation and subsequent fine-tuning. The tool is a unique visualization that allows users to benefit with a few clicks from getting the information they require for their needs, and offers novel scientific indicators to characterize (relatively) rare disease research activity. We discuss the applications of insights derived from this tool for science policy and to support decision-making, and to identify opportunities and potential collaborations and make recommendations for future developments, including a broadening of the scope, and discuss potential novel applications.
A new species of Ultratenuipalpus and redescription of Ultratenuipalpus hainanensis (Wang) (Acari, Tenuipalpidae)
Authors: HE HU-DIE , JIN DAO-CHAO , OCHOA RONALD , YI TIAN-CI
Published: July 2024

The genus Ultratenuipalpus (Acariformes: Tenuipalpidae) is represented by 26 species worldwide. We describe and illustrate Ultratenuipalpus dicranopteris sp. nov. He, Jin & Yi, from Dicranopteris sp. (Gleicheniaceae) from Dicranopteris sp. (Gleicheniaceae). We also redescribe the female and supplement original description with that of the male, deutonymph and protonymph stage of Ultratenuipalpus hainanensis (Wang).
A New Species of the Genus Tropidophorus Duméril, Bibron, 1839 (Reptilia: Squamata: Scincidae) from China-Vietnam Border Region in Southeastern Yunnan Province, China
Authors: WANG KAI , LI LING , MU HAO-NAN , XU SHENG-JING , CHE JING
Published: July 2024

Based on morphological and genetic data, we describe a new species of Tropidophorus from the tropical karst landscape in southeastern Yunnan Province, China, close to the Vietnam border. Phylogenetically, the new species forms a clade with T. baviensis, T. murphyi, and T. hainanus, with p-distances ranging from 4.7–5.1% for the 16S gene and 3.9–6.8% for 12S gene. Morphologically, the new species shares the karst morphotype of Tropidophorus, particularly similar as T. murphyi and T. baviensis, in which all having a dorsally compressed head and body, smooth dorsal head scales, and distinctively keeled body scales. However, the new species can be distinguished from these similar species by numbers of supralabial scales, ventral scales, scales around the tail at the10th subcaudal, and a larger body size. We emphasize the urgency of conservation for the tropical karst landscape in northern Indochina.
Psilocybin and Motor Function: A Triple‐Blind, Dose‐Finding Study in Healthy Participants
Authors: Bhagavan Chiranth , Kanaan Richard , Carter Olivia , Nielsen Glenn , Berlowitz David , Issak Sara , Braat Sabine , Zaloumis Sophie , Attard Zachary , Oliver Georgina , Mayne Deanne , McKernon David , Roebuck Greg , Rucker James , Butler Matthew , Bryson Alexander
Published: July 2024

Background

There has been a resurgence of research into the potential therapeutic benefits of psychedelics for neuropsychiatric disorders. Classic psychedelics, such as psilocybin, exert complex effects on higher cognitive functions such as perception and awareness, but their impact on motor function remains unexplored. Moreover, there is a theoretical rationale for using psychedelics to promote motor retraining in certain neuropsychiatric conditions associated with motor dysfunction. This protocol paper outlines the first study to investigate the feasibility and safety of performing movement tasks during the acute effects of psilocybin in healthy participants. The findings from this study will further our understanding of the impact of psychedelics on motor function, and inform future studies that combine classic psychedelics with motor retraining in clinical populations.

Methods

12 healthy participants will each receive three doses of psilocybin (between 5 and 20 mg) in a randomized order, with each dose administered at least 1 week apart. Participants, the trial physiotherapists, and statisticians will remain blinded to the psilocybin dose. A battery of measures assessing motor function will be completed during the acute drug effects. In addition, measures of safety, pre‐ and post‐dose resting‐state brain activity via functional magnetic resonance imaging, and participants' subjective experience will be assessed.
Theological Opportunity Structures and Christian Right Resistance Against the Liberalization of Family Laws in Norway
Authors: Brekke Torkel
Published: July 2024

This article is a qualitative study of a Christian Right Party in Norway and its origin and growth as a reaction against the liberalization of laws pertaining to same-sex marriage, the adoption of children by same-sex couples, and other family-related matters. In order to analyze the contribution of religion in this political party, and in the movement from which it developed, the article introduces the concept of theological opportunity structures, which is a specific type of discursive opportunity structure. The concept of theological opportunity structures foregrounds the role of religious beliefs, doctrines, and narratives in politics as opposed to the institutional dimensions of religion. It is offered as a theoretical construct to improve analysis of the role of religion in politics.
Too Religious to Protest? Contested Thresholds of Catholic and Muslim “Intransigence” in the French Public Sphere
Authors: Lardy Camille
Published: July 2024

This article examines French Catholics’ recruitment, organization, and policing of Muslim participants in the 2012 to 2013 anti-same-sex-marriage protests La Manif Pour Tous. It argues that French Catholics are alert to forms of public participation which suggest religious “intransigence” (strict religious observance) and can be said to transgress the secular character of the public sphere. Instead, they craft a public presence that can be interpreted as secular, or “liberally” religious-and-secular, without passing the implicit threshold of intransigence. But French Catholics’ efforts to police Muslims’ and their own public visibility reveal the subjectivity and impermanence of the thresholds that are held as proof of religious intransigence. This article contributes ethnographic evidence to the historical and sociological investigation of “liberal” versus “intransigent” forms of French Catholicism and advances the anthropological study of the inequalities and privileges of Muslim and Catholic representation in secular French politics.
Tangled and Bumpy Roads to Gender Equity: Socio-Cultural Insights from Media Stories About Olympic Athletes and Motherhood
Authors: McGannon Kerry R. , Bundon Andrea , Pegoraro Ann , Kulkarni Shaantanu
Published: July 2024

With the 2024 Olympic Games touted as reaching gender parity (i.e., same number of female and male athletes participating), media conversations are continuing about elite athlete mothers. Researchers interrogating media stories of Olympic athlete mothers have shown that their sporting journeys are not straightforward due to tensions linked to gender (in)equity. In this paper we use narrative inquiry as a theoretical lens to explore “comeback themes” synthesized from published media studies of Olympic athlete mothers, along with recent examples of media stories of Olympic athlete mothers. We discuss four comeback themes that include: (in)compatible identities, super mums, veteran status/age, and exposing discrimination, and some implications for gender equity. The first three comebacks perpetuate gender ideologies of heteronormative femininity, good motherhood, ageism, and exceptionalism, which downplay equitable support and change. These themes, along with the exposing discrimination theme, also highlight shifting media representations of motherhood and sport whereby stories expose struggles, realities, and/or structural deficits. We reflect on these themes as a “tangled and bumpy road” to gender equity led by athlete mothers’ voices resulting in changes in maternity rights. These comeback themes show gains in gender equity for sportswomen and highlight areas where more work is needed. Future research recommendations include studying mainstream and social media spaces with an intersectional lens to expand understanding of media stories as pedagogical resources to learn more about motherhood, sport, and gender (in)equity.
Revisiting the Multi-Tiered System of Supports Framework: An Important Mechanism for Realizing Equitable Education in Urban Schools
Authors: Morse Timothy E.
Published: July 2024

Before the COVID-19 pandemic, the multi-tiered system of supports (MTSS) framework was established as a comprehensive, equitable approach for addressing urban students’ academic, behavioral, and social-emotional needs. Still, confusion surrounded its implementation. On returning to in-person instruction, urban educators have been challenged to resurrect their school’s MTSS framework while simultaneously confronting many other issues, such as increased student absenteeism, academic achievement deficits, and staffing shortages. Consequently, revisiting this matter is warranted, particularly concerning operating MTSS frameworks in high-poverty urban schools. Accordingly, this paper explains the design and operation of an MTSS and then discusses its historical evolution and current relevance. Next, the article identifies drivers of well-functioning MTSS frameworks while discussing the circumstances surrounding high-poverty urban schools. The paper concludes with a discussion of a core component of an MTSS framework that urban educators have identified as one for which they need more information: intensifying instruction. Properly addressing this component will equip urban educators with the foundational knowledge they need to design and implement an MTSS framework tailored to their unique circumstances.
Multilevel Confirmatory Factor Analysis Reveals Two Distinct Human–Automation Trust Constructs
Authors: Yamani Yusuke , Long Shelby K. , Sato Tetsuya , Braitman Abby L. , Politowicz Michael S. , Chancey Eric T.
Published: July 2024

Objective

This work examined the relationship of the constructs measured by the trust scales developed by Chancey et al. (2017) and Jian et al. (2000) using a multilevel confirmatory factor analysis (CFA).

Background

Modern theories of automation trust have been proposed based on data collected using trust scales. Chancey et al. (2017) adapted Madsen and Gregor’s (2000) trust scale to align with Lee and See’s (2004) human–automation trust framework. In contrast, Jian et al. (2000) developed a scale empirically with trust and distrust as factors. However, it remains unclear whether these two scales measure the same construct.

Method

We analyzed data collected from previous experiments to investigate the relationship between the two trust scales using a multilevel CFA.

Results

Data provided evidence that Jian et al. (2000) and Chancey et al. (2017) automation trust scales are only weakly related. Trust and distrust are found to be distinct factors in Jian et al.’s (2000) scale, whereas performance, process, and purpose are distinct factors in Chancey et al.’s (2017) trust scale.

Conclusion

The analysis suggested that the two scales purporting to measure human–automation trust are only weakly related.

Application

Trust researchers and automation designers may consider using Chancey et al. (2017) and Jian et al. (2000) scales to capture different characteristics of human–automation trust.
Gujranwala, 14 April 1919: Terror from air and airmindedness in late colonial India
Authors: George Joppan
Published: July 2024

This article revisits one of the earliest instances of British colonial aerial aggression in an urban milieu in South Asia to better understand the normative conceptions of airmindedness, the popular appreciation of aviation. A day after the massacre of unarmed civilians in Jalianwala Bagh, Amritsar, in 1919, three Royal Air Force airplanes armed with bombs and machine guns flew out from Lahore toward Gujranwala in Punjab. The event unleashed a whirlwind of rumours that spread from Lahore to Rangoon, which spoke of the collective fears of aerial violence. If the scant evidence presented by the pilots to the official inquiry into the unrest in Punjab served only to whitewash the record, a peoples’ report that marshalled witness testimonies indicted the colonial state's proclivity for violence. By assembling photographic evidence and crafting a cartographic triangulation of the sites of bombing from their testimonies, the colonial subjects challenged the statist narrative. The asymmetry of vertical violence in Gujranwala was also excavated as political commentary in a novel published in New York by an Indian author. By piecing together these disparate discursive fragments, my article attempts to make a composite sketch of the popular responses to trace a non-Western perspective on airmindedness.
Positive and Negative Rights of Conscience: Balancing When Rights Conflict
Authors: Jones-Nosacek Cynthia
Published: July 2024

Conscientious objection (CO) in medicine has been seen as a negative right, the right to be free from the intervention of others, so as not to be coerced into doing a medical intervention that the objector thinks is immoral. Arguments are now becoming more common calling for protection for the positive right of conscience, the right to perform interventions by the healthcare provider (HCP) even when it goes against the policy of the healthcare institution (HCI) or the law. Rights create obligations. While negative rights only obligate that others not interfere, positive rights create the obligation of others to support the activity. Positive rights of conscience of the HCP impinge on the negative rights of the HCI. They require that the HCI implicitly support the activity of the HCP, which is formal cooperation and can never be justified without the loss of integrity on the part of the HCI. This article will argue, outside of the limitations of CO such as providing care in an emergency when there is no other option, that respect for the negative right of conscience of the HCI outweighs the positive right of the HCP.
Enhancing 3D-printed denture base resins: A review of material innovations
Authors: Majeed Hadeel Fikrat , Hamad Thekra Ismael , Bairam Latifa R
Published: July 2024

The limited physical and mechanical properties of polymethyl methacrylate (PMMA), the current gold standard, necessitates exploring improved denture base materials. While three-dimensional (3D) printing offers accuracy, efficiency, and patient comfort advantages, achieving superior mechanics in 3D-printed denture resins remains challenging despite good biocompatibility and esthetics. This review investigates the potential of innovative materials to address the limitations of 3D-printed denture base materials. Thus, this article is organized to provide a comprehensive overview of recent efforts to enhance 3D-printed denture base materials, highlighting advancements. It critically examines the impact of incorporating various nanoparticles (zirconia, titania, etc.) on these materials’ physical and mechanical properties. Additionally, it delves into recent strategies for nanofiller surface treatment and biocompatibility evaluation and explores potential future directions for polymeric composites in denture applications. The review finds that adding nanoparticles significantly improves performance compared to unmodified resins, and properties can be extensively enhanced through specific modifications, particularly silanized nanoparticles. Optimizing 3D-printed denture acrylics requires a multifaceted approach, with future research prioritizing novel nanomaterials and surface modification techniques for a novel generation of superior performance, esthetically pleasing, and long-lasting dentures.
Examining the Relationship Between Firearm Violence Exposure and Posttraumatic Symptomatology in Adolescents: A Scoping Review
Authors: Lee Esther , Stilwell Sarah M. , Murphy Heather , Mai Shiying , Heinze Justin
Published: July 2024

Firearm-related violence is the leading cause of death for adolescents and can have lifelong ramifications, including to one’s mental health and well-being. Through a scoping review of existing literature published since 1980, the current study describes nuanced pathways through which exposure to firearm violence (direct or indirect) can contribute to the development and exacerbation of posttraumatic symptomatology during adolescence (ages 10–19). Furthermore, this review explores moderators and mediators of this relationship, shedding light on the interplay between individual, familial, and societal factors. Findings from the reviewed studies ( N = 16) demonstrate various links between direct and indirect firearm exposure and short- and long-term posttraumatic symptomatology in adolescents and point to necessary solutions that encompass consistent firearm violence prevention and mental health support. Results can inform future research, policy development, and intervention strategies to mitigate the adverse psychological effects of firearm violence on the vulnerable adolescent population.
Improving ChatGPT's Competency in Generating Effective Business Communication Messages: Integrating Rhetorical Genre Analysis into Prompting Techniques
Authors: Wang Junhua
Published: July 2024

This study explores how prompting techniques, especially those integrated with rhetorical analysis results, may improve the effectiveness of artificial intelligence (AI)-generated business communication messages. I conducted an experiment to assess the effectiveness of these prompting techniques in the context of crafting a negative message generated with ChatGPT 3.5 ( n = 85). A multiple regression was calculated to explore prompting techniques’ impact on the negative message grades and how each technique influences the message grade. The results ( F(4, 80) = 31.84, p < .001), with an adjusted R2 = .595, indicate a positive relationship between prompting techniques and the effectiveness of AI-generated messages. This study also identified challenges related to students’ AI literacy. I conclude the study by recommending practical measures on how to incorporate AI into business and professional writing classrooms.
Improving Proposal Writing by Looking to Information Operations
Authors: Axelrod Seth J.
Published: July 2024

This article examines the subject of persuasion in technical and professional communications (TPC) with a specific focus on proposals in U.S. Government contracting. It demonstrates a fundamental disconnect between the intent of proposals, which is to persuade, and the rhetorical traditions and professional boundaries of technical writers. The analysis draws on the existing rhetorical- and genre-based TPC literature and borrows from theory in other disciplines—management, organizational theory, sociology, and psychology among others. To advance the scholarship on proposals, this analysis is framed within the overall context of a structural analogy to U.S. military Information Operations (IO). Through use of analogy, it is suggested that the IO community's approach to the concepts of “influence,” “narrative,” “target audience,” and “unity of effort” may offer useful insight for State and Federal contractors to consider in their efforts to write persuasive proposals. This analysis is then used to develop a research agenda for the study of proposals. Areas for future research include the science of persuasion and the use of narrative as it relates to proposals, improved rigor in the use of target audience research, and organizational constructs to improve collaborative writing in proposals.