bluuebunny/crossref_metadata_2025 huggingface dataset:
Features of the formation of lambs' adaptive capacity in the first day of life
Authors: Korkh Igor , Boyko Nataliya , Pomutin Іvan , Paliy Anatoliy , Pavlichenko Olena
Published: June 2023

New-born lambs are subjected to significant loads during rearing with the existing technologies of sheep farming. The stability and ability to adapt of newborn animals is not the same and is conditioned by different functional maturity, low resistance, and high susceptibility to extreme biotic and abiotic factors. Because of this, their physiological condition deteriorates, the body defenses decrease, which most often leads to a decrease in productivity, an increase in morbidity and mortality. Knowledge about the development of the clinical condition and thermoregulation in lambs during early ontogenesis is quite limited, which determines the relevance and expediency of the work conducted, the purpose of which was to investigate the peculiarities of the formation of adaptive capacity in newborn lambs during the first day of postnatal rearing. As part of the experiment, it has been determined that the body temperature of the lambs on the first day after birth varied with different intensity from the initial value. This was affected by the differences in the modules of its deviation, which made it possible to distinguish three groups with different levels of thermoregulation processes. Lambs of group I were the most viable, which were born with 5.1 and 9.9% more live weight at a higher metabolic rate of 1.0378 vs. 1.0331 and 1.0300 in lambs of groups II and III and reliably higher by 5.0 and 14.9% of pulse rate parameters and 4.7 and 27.7% of breathing rhythm, thereby ensuring sufficient functioning of thermoregulation mechanisms. It was found that the level and nature of the correlation between live weight and physiological indicators (live weight, pulse and breathing rates) indicate the multi-vector relationship in lambs with different body temperature deviation modules. These dependencies were especially clearly manifested in individuals of the group I (r=-0.522; r=0.362; r=0.707, respectively). It was recorded that the microclimate in the room for keeping ewes and newborn lambs in terms of hydrogen sulfide content almost twice exceeded the technological norm of industry-specific process engineering standard, while other zoohygienic parameters approached its upper limit.
Factores que influyen en la adherencia de pacientes diabéticos dispensarizados en una farmacia comunitaria
Authors: Férnandez Tamayo Yurannis , González Capdeseñur Liset María , Morales González Maraelys , Ricardo Fernández Karla
Published: June 2023

Las complicaciones en pacientes diabéticos pueden estar vinculadas con la falta de adherencia, diversos estudios registran que la mitad de los pacientes no siguen adecuadamente el tratamiento. El objetivo del trabajo fue: determinar los factores que influyen en la adherencia terapéutica de pacientes con Diabetes Mellitus Tipo 2 dispensarizados en la farmacia comunitaria Quintero de Santiago de Cuba. Se realizó un estudio observacional y transversal. La muestra se caracterizó según variables biosociales, clínicas y farmacoterapéuticas. Se analizó el cumplimiento del tratamiento no farmacológico y el farmacológico, estableciendo dos categorías de adherencia: adherentes y no adherentes. Se determinaron los factores que influyeron en la adherencia. Se empleó la estadística descriptiva y chi-cuadrado para el análisis de los datos. El 66,7 % y 49,4 % fueron del sexo femenino y mayores de 60 años, respectivamente. El 82,7 % tuvo hasta dos comorbilidades. El 51,8 % incumplió con el tratamiento no farmacológico y el 50,6 % con el farmacológico, resultando el 54,3 % no adherentes. Se encontró una relación estadísticamente significativa entre la adherencia y el sexo femenino (p=0,0403), la presencia de hasta dos comorbilidades (p=0,0000), la no limitación de la actividad social (p =0,0002), el tiempo de diagnóstico hasta cinco años (p=0,0000) y la accesibilidad al servicio farmacéutico (p=0,0000). Predominaron los pacientes no adherentes. Factores como la edad, no conocer la enfermedad, tener más de tres comorbilidades y más de 10 años de diagnóstico influyeron en la no adherencia. Se deben implementar acciones
Features of post-radiation disturbances in the accumulation of calcium ions in intracellular platelet depots at different times of the post-radiation period
Authors:   International Sakharov Environmental Institute, Belarusian State University, Parkhimovich Olga G. , Bichan Olga D. ,   Belarusian State University, Bulanova Klavdiya Ya. ,   International Sakharov Environmental Institute, Belarusian State University
Published: June 2023

Calcium ions are an important intracellular regulator; an increase in their concentration in the cytoplasm plays a key role in determining the functional activity of platelets associated with platelet aggregation and the release reaction. The main way to reduce the concentration of free calcium ions in the platelet cytoplasm is the activation of Ca2+-ATPases of intracellular depositing structures and the plasma membrane, which reduce the cytoplasmic content of calcium due to its reuptake in the depot (resequestration) and the release of Ca2+ from the cell. Platelets express two Ca2+-ATPase isoforms in different depositor structures (SERCA2b and SERCA3) and two plasma membrane Ca2+-ATPase isoforms (PMCA1b and 4b). The SERCA2b isoform, which is Ca2+-ATPase of the dense tubular system, is inhibited by thapsigargin. The SERCA3 isoform present in acidic organelles has low sensitivity to thapsigargin, but high sensitivity to tBHQ (2,5-di-(tert-butyl)-1,4-hydroquinone). When stimulated with micromolar concentrations of thapsigargin and ionomycin, which cause complete depletion of the calcium depots of the tubular system and acid organelles, differences in the levels of accumulated calcium in the norm and in the post-radiation period are found in a calcium-free medium: an increase in calcium concentration by 1.4 times is noted on the 3rd day. In the structures of the tubular system of platelets, under the action of nmolar concentrations of thapsigargin, which inhibit SER-CA2b Ca2+-ATPase of tubular systems, a change in the content of deposited calcium in irradiated animals was revealed with an increase on the 3rd day. Under conditions of inhibition of Ca2+-ATPase SERCA3 in a calcium-free medium in platelets on the 3rd day after irradiation at a dose of 1 Gy, a more intense release of calcium ions was also noted compared to the control. On the 10th, 30th, 90th day, there were no statistically significant differences in these indicators. In the calcium-containing medium, a more significant intake of calcium ions from the outside into the cytoplasm was observed due to the activation of depot-controlled mechanisms in the post-radiation period, especially on the 3rd and 10th days.
Gündelik Hayatın İzini Sürmek: Yaşlı Kadınların Gündelik Hayat Bilgisinden Turizm Mekânlarına Erişimlerini, Mekânsal Deneyimlerini ve Sınırlılıklarını Anlamak
Authors: KAÇAR Sena , KERVANKIRAN İsmail
Published: June 2023

Bu çalışma yaşlı kadınların gündelik hayat bilgisinden yola çıkarak turizm mekânlarına erişimlerini, yaşadıkları sınırlılıkları ve mücadele stratejilerini ele almaktadır. Çalışmanın amacı, yaşlı kadınların turizm mekânlarındaki cinsiyet ve yaş temelli toplumsal ve mekânsal örgütlenme biçiminin ayrımcı söylem ve temsili üretimlerle ortaya çıkardığı eşitsiz mekânsal ilişkileri incelemektir. Bu amaç doğrultusunda çalışmada nitel araştırma yöntemi izlenerek Antalya il merkezine turizm amaçlı seyahat eden 65 yaş ve üstü 20 kadın gezginle yüz yüze görüşmeler yapılmış ve sahadan toplanan veriler analiz edilmiştir. Araştırmadan çıkan bulgulara göre yaşlı kadınlar gündelik hayatta inşa edilen cinsiyet ve yaş temelli ayrımcı toplumsal ve mekânsal temsilleri sorgulamadan içselleştiren pasif özneler değil, aksine bireysel haklarını savunan, yasaları hatırlatan, toplumsal cinsiyet rollerini aşma eğiliminde olan ve yaşlılık sürecinin getirdikleri ile mücadele etmeye çalışan aktif öznelerdir.
DA MEMÓRIA À EMOÇÃO
Authors: Andrade Joachim
Published: June 2023

As religiões tradicionais estão na experiência de travessia, pois passam por uma crise aguda no contexto contemporâneo. A oferta do conteúdo dessas tradições não tem mais efeito, uma vez que o êxodo de uma tradição à outra é visível. Elas fizeram tentativas de frear essas migrações, sem modificar suas próprias estruturas, portanto, não tiveram sucesso. A oferta do conteúdo religioso pelas novas manifestações religiosas parece ter uma acolhida melhor por parte da população que está buscando as saídas para as questões espirituais. Dentro desse contexto, encontramos a fricção entre a memória das religiões tradicionais e emoção dos movimentos pentecostais, onde existe uma visível preferência da população pela emoção do que pela memória. O presente artigo fornece uma visão geral do fenômeno da religião no mundo, apontando a raiz da crise e crescimento gradativo das novas manifestações religiosas, entre os quais se encontra o pentecostalismo contemporâneo.
PENTECOSTALISMO BRASILEIRO
Authors: Queiroz Bruno dos Santos
Published: June 2023

A glossolalia consiste na experiência tida como sobrenatural de falar em línguas estranhas desconhecidas dos idiomas humanos. O objetivo deste artigo consiste em considerar a visão pentecostal sobre a glossolalia como evidência do batismo no Espírito Santo. Para tanto, será considerada a posição da maior denominação evangélica brasileira, as Assembleias de Deus, sobre o assunto. Em seguida, será discutida a base bíblico-teológica da doutrina e, por fim, será considerada em especial a experiência pentecostal brasileira em relação ao batismo no Espírito Santo e ao falar em línguas. Conclui-se que a glossolalia pode ser entendida como uma experiência místico-religiosa que carrega consigo um caráter de inefabilidade.
OS PENTECOSTAIS EM CAMPOS DOS GOYTACAZES – RJ
Authors: Santos Júnior Paulo Jonas dos
Published: June 2023

O pentecostalismo é uma ala do cristianismo que tem chamado a atenção de estudiosos da sociedade brasileira nos últimos anos. O presente artigo tem por objetivo analisar o crescimento do pentecostalismo na cidade de Campos dos Goytacazes e de igual modo realizar um levantamento do perfil sociocultural dos seguidores dessa doutrina religiosa. Campos dos Goytacazes é uma cidade estratégica para o Estado do Rio de Janeiro e para o Brasil, uma vez que é um importante polo petrolífero. Para as análises consultamos artigos e periódicos especializados que discutem o assunto. Por fim, foi possível observar que a dinâmica pentecostal está em pleno desenvolvimento na cidade de Campos dos Goytacazes, o que tem levado esse segmento a alcançar altos índices de crescimento no município.
Hubungan Antara Stress Kerja dan Kualitas Tidur Dengan Subjective Well-Being pada Dosen Uhamka Selama Pandemi Covid-19
Authors: Andriany Anissa Rizky , Pertiwi Mahesti
Published: June 2023

The Covid-19 pandemic has brought about changes in education that are evident in the process of teaching and learning activities, which were originally carried out in the campus environment turned into distance lectures (PJJ). This study aims to find out whether or not there is a relationship between work stress and sleep quality with subjective well-being in lecturers at UHAMKA. This study involved 85 lecturers who worked at UHAMKA. The research instruments used are the Work Stress Questionnaire, the Pittsburgh Sleep Quality Index,and thewell-being bjectiveSu.  The results showed that there was a relationship between work stress and subjective well-being in UHAMKA lecturers during the covid-19 pandemic, a negative relationship. That is, the higher the work stress experienced by lecturers, the lower subjective well-being,and vice versa. Furthermore, there is a relationship between sleep quality and subjective well-being in UHAMKA lecturers, with the direction of positive relationships, showing that the higher the quality of sleep that lecturers have, the higher subjective well-being,and vice versa. The conclusion of this study, there is a relationship between work stress and sleep quality with subjective well-being in UHAMKA lecturers during covid-19. This shows that work stress and sleep quality simultaneously are both associated with subjective well-being in UHAMKA lecturers during covid-19, inother words Ha was accepted and Ho wasrejected
Pemanfaatan Container Menjadi Ruang Isolasi Apung Sebagai Alternatif Bagi Pasien Covid-19
Authors: Lazuardi Siti Dwi , Muaz Akhdan Muhammad , Zahroh Dina Fatimatuz , Airlangga Altalariq Pranantha Yudha , Saputri Afyfah Ramadhani Dias
Published: June 2023

Kasus COVID-19 hingga saat ini terus mengalami peningkatan, terlalu banyaknya pasien yang membutuhkan perawatan intensif mengakibatkan rumah sakit mengalami kondisi overloaded capacity. Dalam rangka meminimalisir adanya pasien rawat mandiri dan berisiko adanya cluster keluarga, maka pemanfaatan container menjadi ruang isolasi apung sebagai alternatif bagi masyarakat untuk mendapat penanganan intensif COVID-19. Pemanfaatan container bekas 20 feet dipadukan dengan alas untuk mengapung berbahan HDPE (High-Density Polyethylene) dan alas pijakan WPC (Wood Plastic Composite). Dalam mempertimbangkan besaran biaya serta mengukur keoptimalan dari manfaat penelitian, maka penilitian ini menggunakan metode CBA (Cost-Benefit Analysis) dan metode BCR (Benefit Cost Ratio) untuk menguji kelayakan dari penelitian ini. Hasil penelitian menunjukan bahwa pemanfaatan container bekas menjadi ruang isolasi apung termasuk dalam kategori baik, dimana penelitian ini dapat menekan angka pasien isolasi mandiri sebesar 35% dan hasil perhitungan manfaat memiliki rasio sebesar 1,02 dan menghasilkan nilai NPV positif dengan batasan kelayakan yaitu BCR > 1, dan NPV > 1. Dari hasil penelitian tersebut, dapat disimpulkan bahwa, ruang isolasi apung ini layak untuk direalisasikan atau dioperasikan.
Attractiveness, Trustworthiness and Purchase Intention in Social Media Instagram: The Moderating Role of The Number of Followers
Authors: Tamara Dewi , Rafly Rudy , Mersi Arimbi
Published: June 2023

This study examines the influence of influencers' credibility on purchase intention on Instagram. The framework in this study includes attractiveness and trustworthiness as an indicator of influencer credibility and independent variables, number of followers as moderator, and purchase intention as dependent variable. Respondents in this study were 200 Instagram users in Indonesia who had done via Instagram. The results show that attractiveness and trust have a positive effect on purchase intention. And, the number of followers moderates the relationship between attractiveness to purchase intention and trustworthiness to purchase intention. In addition, the results of this study also prove that the number of followers has a direct influence on purchase intention. This study contributes to the product endorsement literature, how an influencer can increase the purchase intention of a consumer on Instagram social media.
Peranan Destinasi Wisata Alam dalam Mengembangkan Daerah dan Masyarakat Sekitar
Authors: Multazam Muhammad Mas , Malihah Elly , Andari Rini
Published: June 2023

The role of Natural Tourism Destinations is considered very important to develop the area and surrounding communities because the development of the area and the surrounding community is the responsibility of the manager of the destination. In this study, the authors examined the importance of the role of managers, the impact that society gets and the benefits that society feels. This research aims to find out the extent to which Capolaga Natural Tourism implements the concept of CSR through the development of the surrounding area and its effects or benefits both materially and non-materially. By talking about efforts to improve the quality and standard of living of the people around the Capolaga Natural Tourism area. This study uses field observation approach methods, resource interviews, and literature studies with descriptive analysis.  This study was conducted by observing the impact that occurs on capolaga natural tourism on the community. the study occurred on December 11-12.
Kesesuaian Resep ISPA Non Pneumonia dengan Kriteria Por Nasional di Puskesmas Kabupaten Sleman Yogyakarta
Authors: Christasani Putu Dyana
Published: June 2023

Pharmacists at the Puskesmas have a role in monitoring and fostering the Rational Use of Drugs (POR) to prevent and overcome the problems in drug administration. The high irrational use of drugs and the bad consequences of resistance is one of the reasons why this research needs to be done. The purpose of this study was to determine the suitability of prescribing non-pneumonia ARI drugs with the National POR indicator at the Sleman District Health Center, Yogyakarta. This research uses observational descriptive research with cross-sectional design. The research data obtained from non-pneumonia ARI prescriptions for the period January-June 2020. Data were analyzed descriptively by calculating the percentage rationality of prescribing non-pneumonia ARI drugs and their conformity with the National POR indicator. The results showed that during the study period, patients who visited the Puskesmas were dominated by women (56.45%) and the age group was 26-45 years (26.57%). From 8 Puskesmas in Sleman Regency, only 3 Puskesmas (37.5%) with non-pneumonia ARI prescriptions in each month that met the National POR criteria. This study concludes that not all puskesmas in Sleman Regency, Yogyakarta that included in the study meet the rationality standard for prescribing non-pneumonia ARI by the National POR criteria
Evaluasi Kinerja Penyedia Jasa pada Pekerjaan Preservasi Jalan Nasional dengan Metode Ahp: Ruas Jalan Simpang Kawat – Aek Kanopan -Rantau Prapat - BTS. Provinsi Riau
Authors: Anugrah Riski , Tarigan Ahmad Perwira Mulia , Hasibuan Gina Cynthia Raphita
Published: June 2023

Road preservation activities have an important role in maintaining road conditions so that they continue to function in serving traffic so that they can extend the service life of the road and ensure traffic safety. One of the road preservation activities that affect the success of the work is the capacity and capability of the service provider. The Service Provider as one of the procurement actors is also an important element that must be considered and will determine and influence the success of project governance. This study attempts to evaluate the performance of service providers on road preservation work based on road performance indicators using the Analytic Hierarchy Process (AHP) method. Service provider performance criteria will be identified as Road Performance Indicators (IKJ), Past Performance (KT), Safety Performance (KK), Financial Stability (SF), and Technical Resource Performance (KSDT). The weight values ​​from the results of the AHP method analysis for each criterion are: IKJ (0.289), KT (0.122), KK (0.203), SF (0.135), and KSDT (0.251). The performance of the preservation work service provider gets a performance score of 2,868 with a good predicate (2 to 3).
Peran Guru dalam Meningkatkan Minat Berwirausaha Siswa Sekolah Menengah Kejuruan (SMK)
Authors: Minarsih Minarsih , Putri Sagala Susana Verawati , Maysaroh Maysaroh
Published: June 2023

Vocational High School (SMK) as a type of formal school which organizes entrepreneurship education that can direct students to become graduates who are ready to enter professionally and participate in the business and industrial world. So that in this study the aim is to know how the teacher's role in motivating and coaching students to build an entrepreneurial spirit in students. This research was conducted using a qualitative approach with a literature study method. Teachers play an important role as facilitators and motivators in developing entrepreneurship for students to increase students' interest in entrepreneurship. With entrepreneurship learning received by students, it is hoped that they can balance theory and practice about entrepreneurship and can have an influence in increasing students' interest in entrepreneurship. If schools want their students to have a high interest in entrepreneurship, then the role of a creative teacher in providing entrepreneurship subjects, providing guidance, and providing coaching is a teacher who can provide materials and teaching methods for a successful entrepreneur
Pengaruh Personal Selling, Digital Marketing, dan Brand Image terhadap Keputusan Pembukaan Rekening
Authors: Prastiwi Anggita , Hamidy Siregar Muhammad Faiz , Imanuel Yaman Taruna
Published: June 2023

This study aims to test and analyze empirically the effect of the influence of personal selling, digital marketing, and brand image on the decision to open a Si Mantap Pension Account at Bank Mandiri Taspen. The research methodology used in this research is quantitative. The data used are primary data obtained from distributing questionnaires with a Likert scale (1-5). The population in this study is the customers who have opened a Si Mantap Pension account at Bank Mandiri Taspen, with a sample of 390 people. Data analysis for hypothesis testing using multiple linear regression with the help of PLS Path Modeling (PLS-PM) software. The results showed that Personal Selling, Digital Marketing and Brand Image had a significant positive effect on the Si Mantap Pension Account Opening Decision at Bank Mandiri Taspen
Pengaruh Total Liabilitas dan Total Ekuitas terhadap Laba
Authors: Wardoyo Dwi Urip , Putri Errina Aprilia , Hasani Nisa Aulia
Published: June 2023

This study aims to determine and analyze the role of total liabilities and total equity whether or not it can affect profits or not in a company. This research was conducted by using the method or reviewing previous studies in a structured manner so as to identify the effect or absence of total liabilities and total equity on earnings. The data source used in this study is the data source of scientific articles on Google Scholar in 2018-2021 that are relevant according to the research. This type of research includes research (qualitative).
Kajian Rasio Profitabilitas dan Rasio Solvabilitas Pt Astra International Tbk
Authors: Murtiningtyas Dinda Putri , Giovanni Axel
Published: June 2023

Assessment of financial performance for companies is important because it is used to see the company's performance in the future by knowing the overall picture of the financial position. The purpose of this study is to examine the company's financial performance using the profitability ratios calculated using the Gross Profit Margin, Net Profit Margin, Return On Assets, Return On Equity and the solvency ratio calculated using the Debt to asset ratio and the Debt to equity ratio. The method used in this research is descriptive study with the main object of this research is PT Astra International Tbk. The type of data used is secondary data, secondary data obtained from company financial statements that have been audited for the 2017-2020 period. The method of analysis in this study is horizontal analysis by comparing financial statements with different periods. The results in the study using the profitability ratios from the 2017-2020 period on Gross Profit Margin and Net Profit Margin fluctuated which indicated that the company's operational performance was not good, Return On Equity had decreased and Return On Assets was in a fluctuating condition. For calculations using the solvency ratio has decreased, which means the company's financial performance is getting better and more effective.
Analisis Senyawa Dolutegravir dalam Berbagai Sampel Biologis
Authors: Nafis Alya , Al Bara Bismar , Farhani Deviana , Maharani Dhavina , Prasetyo Fajar , Mukti Galih Ibnu , Sa’diyyah Nur
Published: June 2023

Bioanalysis is a chemical analysis used to determine the levels of xenobiotic substances and biotic substances in biological systems. In the pharmaceutical world, bioanalysis plays a role in the development of new drugs, monitoring drug therapy, and also bioequivalence. The bioanalytic research that will be discussed in this journal is about the analysis of dolutegravir in urine, saliva (saliva), and blood plasma samples. The technique used can detect the content of dolutegravir in urine, saliva, and blood plasma. The purpose of this study was to observe the presence of dolutegravir using various methods in various biological samples, namely blood plasma, saliva, and urine. The method used in making this article review is the collection of literature from existing journal sources relating to the analysis of dolutegravir on biological samples sourced from google, google scholar, and e-books using the keywords "dolutegravir", "bioanalysis", "blood ”, “urine”, and “saliva” in a literature search. Further search can be seen manually in writing a bibliography. The results showed that the method used in the analysis of blood plasma and saliva samples was able to provide accurate results. However, the method used in urine samples is not yet accurate, so other methods are needed to get accurate results.
Peningkatan Keterampilan Berpikir Kritis Siswa SMAN 1 Tambun Selatan Melalui Permainan Werewolf Card Game
Authors: Ramadhani Muhammad Taufik , Ruyadi Yadi Ruyadi , Supriyono Supriyono Supriyono
Published: June 2023

The 21st century is an era that has a major impact on all aspects of human life, especially in the field of education. In order to improve the level of education in accordance with the needs of the system, this research focuses on improving 4C skills, especially critical thinking skills by involving the Werewolf Card Game learning media, which is expected to be a new innovation in the learning process. The method used in this research is descriptive statistics with a quantitative approach. The findings in this study are that there is a strong influence from the use of the Werewolf Card Game learning media on the critical thinking skills of the students of SMA Negeri 1 Tambun Selatan.
Analisis Resiko Kegagalan Proses Kain jadi Polyester Menggunakan Metode FMEA pada PT XYZ Karawang
Authors: Fernandi Rian Fernandi
Published: June 2023

Proper quality control and clear stages and provide innovation in preventing and solving problems faced by the company. PT. XYZ Karawang is a textile industry company that produces polyester and cotton fabrics. In fact, this company still finds products with non-standard quality. From previous research data, the number of defects in polyester fabric tends to be quite high and does not comply with the standard, which exceeds the 2% set by the company. Meanwhile, the average product defect is 7,412 meters, about 5.4% of the total production each month is greater than cotton cloth. Therefore, the problem that arises is from polyester fabric which results in loss of cost of goods based on defects. FMEA is a technique used to identify the presence or potential of failures or problems in the design, process or structure of a sistem service before they occur, to prevent unwanted incidents and protect employees from occupational accidents and diseases by taking the necessary action. failures in the analyzed sistem are identified by FMEA, which enables the decision maker to take the necessary risk reduction actions. The purpose of this study is to analyze the failure modes that cause product defects using the FMEA method. The results of the research conducted based on the Risk Priority Number (RPN) there are 11 failure modes which are assumed to be the higher the failure mode RPN, the greater the risk for product failure and low quality. Of the 11 failure modes, the highest RPN value was 378, namely incomplete drug dissolution and the lowest was 27 with failure in the drug storage area. The factors that cause color spot defects on polyester fabrics are humans, raw materials, machines, methods used and the environment. In conclusion, the risk of failure in this study as a priority in the proposed improvement at the company PT. XYZ Karawang. Suggestions for improvement are given to the company as a whole to pay more attention to the factors causing the problem of fabric defects and as material for consideration in the company.
Fungsi Budgetary dan Regulatory Penerimaan Negara Bukan Pajak (PNBP) di Indonesia
Authors: Ditisrama Tinton Ditisrama , Sinaulan Ramlani Lina , Ismail Ismail Ismail
Published: June 2023

Non-Tax Revenue (PNBP) is one of the instruments of state revenue excluding tax revenues, and grants are the second largest contributor to revenue after tax revenues in the APBN. Similar to tax revenues, the constitutionality of PNBP is also regulated in Article 23A of the 1945 Constitution of the Republic of Indonesia. Furthermore, the legal politics of the constitutionality of PNBP is described in Law Number 9 of 2018 concerning PNBP. In principle, PNBP has two functions, namely the budgetary function and the regulatory function. The two functions of PNBP are the spirit or soul of PNBP, meaning that both functions must be ensured that they really work and synergize with each other, without this, the existence of PNBP in supporting state/government activities in order to achieve people's welfare will be insignificant and not strategic. The method used in this study is juridical-normative, with this method the author tries to explain how the implementation of the budgetary function and the regulatory function of PNBP in supporting the implementation of state/government activities in Indonesia.
Analisis Rasio Arus Kas Untuk Mengukur Kinerja Keuangan Pada Pt Indofood Sukses Makmur Tbk. Periode 2018-2020
Authors: Febryanti Febryanti , Noviyana Syntha
Published: June 2023

The purpose of this study was to determine and analyze the financial performance as measured by the cash flow ratio at PT. Indofood Sukses Makmur Tbk. 2018-2020 period. This study uses the following cash flow ratio analysis methods: operating cash flow ratio (AKO), fund flow coverage ratio (CAD), cash to interest coverage ratio (CKB), cash to current debt coverage ratio (CKHL), capital expenditure ratio ( PM), total debt ratio (TH). The type of data used in this research is quantitative data. Sources of data used in this study is secondary data. In the form of a Financial Statement consisting of a Balance Sheet, Income Statement and Cash Flow Statement at PT. Indofood Sukses Makmur Tbk period 2018-2020. The data collection technique used in this study to obtain the data and information needed is a documentation study, namely through the website of the Indonesia Stock Exchange (www.idx.co.id). The author uses quantitative analysis techniques, namely calculating and analyzing the relevant results from the financial statements, using the cash flow statement ratio. The results of the study note that the financial performance of PT. Indofood Sukses Makmur Tbk for the 2018-2020 period shows that there are three cash flow ratios whose values ​​are still below the applicable standard criteria because the company has not been able to meet current obligations and long-term debt on time but the company can cover interest costs, capital expenditures, and is able to pay taxes. of the cash flow generated by the company.
Kintamani Tourism Destinations: A Study Of Tourist Perceptions Milenial Generation
Authors: Prasiasa Dewa Putu Oka , Widari Dewa Ayu Diyah Sri
Published: June 2023

The purpose of this study is to examine the perceptions of the millennial generation towards Kintamani as a tourism destination from three aspects, namely attractions, facilities and accessibility. As a qualitative research, data analysis was carried out in a qualitative descriptive manner. The sample of this study was 99 people, determined by the Slovin method, consisting of 89 millennial generation domestic tourists and 11 millennial generation foreign tourists. The results showed that Kintamani Tourism Destinations for attractions were considered very good with an average value of 4.46; facilities are considered good with an average value of 3.67; and accessibility is considered good with an average value of 3.91. This study also recommends the need to improve the quality and quantity of supporting facilities for the Kintamani Tourism Destination such as tourism information centers, public toilets, street lighting, money changers, parking lots, and the quality of roads in the Kintamani Tourism Destination area.
The Marketing Of Tourism Villages Through Annual Event: Case Study Of Penglipuran Village Festival
Authors: Putra I Nengah Sandi Artha , Arini Ni Nyoman , Raditya I Putu Tiana
Published: June 2023

Tourism villages in their development must have a good marketing strategy. Many tourist villages are not developing and progressing because the management and marketing aspects are not carried out properly. The development of a tourist village through an annual event strategy is one of the strategies carried out by independent tourism villages such as the Penglipuran Tourism Village. This study aims to examine the marketing strategy of Penglipuran Tourism Village through an annual event. Two objects that will be studied in the event are event management and marketing strategy. A qualitative approach is the method used in this study. The in-depth interview technique is a technique used to search for data in depth with a purposive sampling technique. The results of this study indicate that there is good event management carried out by the committee which consists of aspects of research, design, planning, coordinating and evaluating. The eight elements of the marketing mix are also applied in the event marketing strategy, such as product, price, place, promotion, people, packaging, programming and partnership aspects. Penglipuran Village Festival as an annual event is managed independently based on the community and is consistently carried out every year. This event has a good impact on the existence of tourism village branding, and provides economic, socio-cultural and environmental welfare benefits.
Analysis Marketing Strategy Of Phenom Event Indonesia During The Covid-19 Pandemic
Authors: Halim Deddy Kurniawan , Pramesti Dinar Sukma , Ratnasari Heidy
Published: June 2023

The MICE industry is one of the tourism industries affected by covid-19 pandemic. Phenom Event Indonesia (PEI) is one of the EOs engaged in the field of MICE organizing services which have also been affected by the co-19 pandemic. It's just that, they have implemented the right marketing strategy so that the impact of the pandemic does not make PEI go out of business. This study aims to analyze the marketing strategy used by PEI to maintain its company during a pandemic. The research method uses qualitative research methods. Data obtained through interviews, literature studies and internet studies. The theory used is marketing theory which consists of product, price, place, and promotion. The results of the study reveal that the marketing strategy used by PEI to survive in the midst of the covid-19 pandemic, namely by: 1) Products, namely by offering new virtual hybrid studio products and equipping themselves with CHSE certificates, 2) The pricing strategy used by PEI is to adjust the scale events and budgets provided from clients with a negotiation process, 3) Location Strategy by utilizing PEI's strategic offices to become restaurants, bars and pubs that can be used for small-scale event venues, 4) Judging from PEI's promotion using digital marketing with a YouTube account and sales calls to all repeater clients as well as changing the target market and always providing feedback in the form of souvenirs or gifts to clients. It is hoped that the results of the research can be used as reference material for EO's marketing strategy when facing pandemics in the future.
Edema pulmonar neurogénico secundario a una hemorragia subaracnoidea. Presentación de un caso clínico y revisión de la literatura
Authors: López Daniel Alejandro Montalvo , Reyes Jocelin Reyes , Vera Claudia García , Quintana Carlos Alberto Delgado , Sedas Gastón Daniel Martínez
Published: June 2023

La hemorragia subaracnoidea espontánea (HSA) representa del 2% al 7% de todos los accidentes cerebrovasculares, documentándose que hasta el 5% de los pacientes fallece antes de llegar al hospital o de obtener una prueba de imagen. La morbi-mortalidad de esta patología radica en factores modificables y no modificables que preceden a esta enfermedad. El edema pulmonar neurogénico (EPN), es una condición clínica que se manifiesta como dificultad respiratoria aguda que se presenta junto con una lesión neurológica severa, generalmente es subdiagnosticado. Presentamos el caso clínico de una mujer de mediana edad, con edema pulmonar agudo secundario a una hemorragia subaracnoidea. Se realiza una revisión de la literatura con especial énfasis en las implicaciones clínicas y el tratamiento.
Psychology of Loss and Grief
Authors: Ghazaryan Isabella
Published: June 2023

This manual presents the psychological patterns of living with loss, the stages of mourning, as well as the psychotherapeutic techniques aimed at alleviating the psychological state of people who have experienced a loss. The manual is useful for practicing psychologists, master's students of psychological departments of universities, as well as for specialists in areas related to psychology.
Pengaruh Pemberian Tepung Kunyit (Curcuma domestica Val.) pada Pakan terhadap Konsumsi Pakan dan Produksi Telur Burung Puyuh (Coturnix japonica)
Authors: Heriyani Heriyani , Munir Munir , Irmayani Irmayani
Published: June 2023

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dari penambahan tepung kunyit (Curcuma domestica Val.) pada pakan terhadap konsumsi pakan dan produksi telur burung puyuh. Penelitian ini menggunakan rancangan acak lengkap dan dianalisis menggunakan sidik ragam (ANOVA).  Perlakuan level tepung kunyit terdiri dari 4 taraf yaitu P0 (Kontrol), P1 (5%), P2 (10%), dan P3 (15%). Setiap perlakuan terdiri dari 3 ulangan sehingga terdapat 12 unit pengamatan dengan menggunakan 120 ekor burung puyuh (10 ekor/unit). Dari hasil penelitian ini, diketahui bahwa pemberian tepung Kunyit dalam pakan burung puyuh berpengaruh (P<0.01) terhadap konsumsi pakan namun tidak berpengaruh (P>0.05) pada produksi telur burung puyuh. Hasil Konsumsi pakan yaitu P0 (22 g/ekor/hari), P1 (21.33 g/ekor/hari), P2 (20.67 g/ekor/hari), dan P3 (18.5 g/ekor/hari). Sedangkan nilai produksi telur yaitu 53.33-73.33%. Berdasarkan dari hasil penelitian dapat disimpulkan bahwa suplementasi tepung kunyit 5-15% dalam pakan menurunkan konsumsi pakan  burung puyuh namun tidak mempengaruhi produksi telur .
Comparison of four electrocardiographic criteria for the detection of cardiac abnormalities in Singapore athletes
Authors: Lim Benji , Lim Baoying , Hamzah Fadzil , Lim Ang Tee , Ng Chung Sien , Tan Benedict , Tong Khim Leng
Published: June 2023

Introduction: Sudden cardiac death in athletes is a rare occurrence, the most common cause being hypertrophic cardiomyopathy, which increases the risk of sustained ventricular tachycardia or ventricular fibrillation. Most of these young athletes are asymptomatic prior to the cardiac arrest. Several electrocardiogram criteria such as the European Society of Cardiology group 2 Criteria changes, Seattle Criteria, Refined Criteria, and most recently the 2017 International Criteria, have sought to improve the accuracy of identifying these at-risk athletes during pre-participation screening while minimising unnecessary investigations for the majority of athletes at low risk. We aimed to compare the above four criteria in our local athlete population to identify which criterion performed the best in detecting cardiac abnormalities on echocardiography.
Method: Out of 1,515 athletes included in Changi General Hospital, Singapore registry between June 2007 and June 2014, the electrocardiograms of 270 athletes with further cardiac investigations were analysed. We compared the above four electrocardiographic criteria to evaluate which performed best for detecting cardiac abnormalities on echocardiography in our Southeast Asian athlete population.
Results: The European Society of Cardiology, Seattle, Refined and 2017 International Criteria had a sensitivity of 20%, 0%, 20% and 5%, respectively; a specificity of 64%, 93%, 84% and 97%, respectively; a positive predictive value of 4%, 0%, 9% and 11%, respectively; and a negative predictive value of 91%, 92%, 93% and 93%, respectively for detecting abnormalities on echocardiography.
Conclusion: The latest 2017 International Criteria performed the best as it had the highest specificity and positive predictive value, joint highest negative predictive value, and lowest false positive rate.

Keywords: Athlete, cardiology, electrocardiogram, pre-participation screening, sports medicine, sudden death
Clinical efficacy of primary human papillomavirus (HPV) screening with partial genotyping for HPV-16 and HPV-18 subtypes in women from 25 years old
Authors: Ang Joella Xiaohong , Lee Wai Yen , Tay Sun Kuie
Published: June 2023

Introduction: Cervical screening programmes differ in the age of women recommended for primary human papillomavirus (HPV) testing. This study aims to determine the clinical efficacy and impact of 14-high-risk HPV DNA testing for women from 25 years old.
Method: This was a retrospective analysis of data collected prospectively from women 25 years or older who attended hospital-based gynaecology clinics for cervical screening. Women with history of cervical neoplasia or abnormal cytology were excluded. High-risk HPV DNA testing with partial genotyping for HPV-16 and HPV-18 were performed on cobas 4800 System (Roche Diagnostics International AG, Rotkreuz, Switzerland). Women tested positive for the 12 other high-risk HPV subtypes (HPV-12 other) had a reflex cytology test. Positive screening included positive for HPV-16 and/or HPV-18, HPV-12 other with cytology abnormalities equal to or greater than atypical squamous cells of undetermined significance, and repeated positive HPV at 12 months. HPV detection and colposcopy referral rates, and detection of high-grade neoplasia were determined.
Results: Of 10,967 women studied, 822 (7.50%) were HPV DNA positive. The overall discharge rate to routine screening according to screening protocol was 93.1%. Colposcopy referral rate was 4.4%. The screening detected 41 cervical intraepithelial neoplasia grade 2+ (CIN2+) (0.37%) and 31 (0.28%) CIN3+. The number of colposcopies needed per case of CIN2+ was 9.5, similar for women below and above 30 years old. The number of colposcopies needed per case of CIN3+ for HPV-16 positivity was 8.5, compared to 17.0 for other categories (P=0.040). Colposcopy efficacy was similar for HPV-18 and HPV-12 other positivity with abnormal cytology.
Conclusion: Taking CIN2+ detection and colposcopy referral rate as endpoints, HPV testing in Singapore can be extended to include women from 25 years old.

Keywords: Cervical cancer screening, cervical intraepithelial neoplasia, colposcopy, obstetrics and gynaecology, Pap smear
Preventive Nephrology: A Time for Action
Authors: Vathsala A , Yap HK
Published: June 2023

The incidence of new end-stage renal failure (ESRF) treated with dialysis in Singapore has risen from 96 per million population (pmp) in 1992 to 167 pmp in 2000.1,2 This near-doubling is not unique to Singapore, and many other Asian countries have seen a similar increase in the incidence of ESRF, in large part due to an increasing incidence of the risk factors for renal disease. Consequent to this high incidence of ESRF, at the end of 2002, an estimated 301,649 patients were on dialysis in Asia.3
Incidence and Predictors of Falls in the Chinese Elderly
Authors: Chu LW , Chi I , Chiu AYY
Published: June 2023

Introduction: This is the first prospective longitudinal study carried out in a Chinese elderly population with the objective of identifying the incidence and predictors of falls.

Materials and Methods: This is a population-based cohort study in Hong Kong with 1517 ambulatory elderly Chinese recruited using a multi-stage sampling method. Baseline data on demographic, comorbid diseases, drugs, Activities of Daily Living (ADL) [Barthel Index and Lawton’s Instrumental Activities of Daily Living (IADL)], Geriatric Depression Scale (GDS-15), cognitive assessment by the Abbreviated Mental Test (AMT), fear of falling, self-perceived mobility problem, hand grip strength, lower limb power, balance and gait tests were performed. Every subject was followed up for 1 year.
Results: Four hundred and one falls occurred in 294 fallers (19.3%) over 1 year of follow-up. The prevalence of falls and recurrent falls were 19.3% and 4.75%, respectively. The incidences of falls (i.e., the fall events) were 220, 324 and 270 per 1000 person-years for men, women and both gender, respectively. The independent predictors of falls were previous history of falls, advancing age, Parkinson’s disease, knee extension power and gait speed. The independent predictors of recurrent falls were previous history of falls, self-perceived mobility problem, the knee extension strength and the Total Mobility Score of the Tinetti Balance and Gait Evaluation.

Conclusions: The incidence of falls in the Chinese elderly was 270 per 1000 person-years. History of falls, old age, Parkinson’s disease, decreased lower limb power and impairment in balance and gait function were important independent predictors of falls or recurrent falls in the Chinese elderly. Effective fall prevention programmes targeted at improving these risk factors for falls should be developed for the Chinese elderly in Hong Kong and Asia.

Key words: Balance, Gait, Hong Kong, Strength
Prevalence of Fascioliasis among Cattle and Goats Slaughtered in Abattoirs within Sagbama Community and Yenagoa Metropolis, Bayelsa State
Authors:   Department of Biology, Isaac Jasper Boro College of Education, Sagbama, Bayelsa State., Gbeghebo Ayibadinipre Jennis , Dominic Araka Akugbenebibo ,   Department of Biology, Bayelsa Medical University, Yenagoa, Bayelsa State., Sarah Shine Ebiemi ,   Department of Biology, Isaac Jasper Boro College of Education, Sagbama, Bayelsa State.
Published: June 2023

The study of the prevalence of fascioliasis among cattle and goats slaughtered at abattoirs in Sagbama community and Yenagoa metropolis, Bayelsa State was undertaken from July to December, 2022. A total of 60 bile samples were collected from the animals (30 from cattle and 30 from goats). The bile sample from each animal was examined using sedimentation method and microscopically examined for the presence of Fasciola eggs. The results showed that 34(56.7%) out of the 60 cattle and goats were infected with Fasciola hepatica. The distribution of infection showed that cattle had the highest prevalence of 70% while goats had 43.3% prevalence. Sex-based prevalence showed 73.3% and 66.7% for male and female cattle respectively while male and female goats recorded 46.7% and 40% prevalence respectively. Also, the prevalence was higher among samples collected from Yenagoa (Etegwe/Tombia abattoir) (66.7%) and was lower among those collected from Sagbama abattoir (46.7). Regular inspection of animals slaughtered at abattoirs and monitoring of butchers will reduce consumption of infected meat and subsequent reduction of the prevalence of fascioliasis in the study areas.