bluuebunny/crossref_metadata_2025 huggingface dataset:
A Spanish Version of the Achievement Task Value Scale for University Students: Internal, Convergent, and Criterion Validity and Reliability in Argentinian Students
Authors: Sánchez-Rosas Javier , Lou Yu-Chiung , Lin Hsiao-Fang , Larroza Silvana
Published: August 2018

Objective: An Achievement Task Value Scale Spanish Language Adjusted Version, assessing task value items corresponding to importance, utility, interest and cost, was evaluated regarding its psychometric properties, in a sample of Argentine students.Method: In order to assess internal structure, exploratory and confirmatory strategies have been used. Besides, scale convergence was assessed by relating them with a one-dimensional task value scale. Evidences of criterion validity were supported by relating scales with enjoyment, achievement goals, and attention. Finally, internal consistency was estimated using Cronbach’s Alpha and Omega coefficients.Conclusions: Results allow to state that this version of the instrument makes it possible to assess, in a reliable and valid way, three components of task value: utility, interest, and cost.
Investigaciones sobre ideación suicida en Colombia, 2010-2016
Authors: Salamanca Camargo Yenny , Siabato Macias Elsa Fernanda
Published: August 2018

Introducción: la ideación suicida ha sido considerada como la primera etapa del espectro suicida y, por consiguiente, el principal predictor de futuros intentos de suicidio e incluso de suicidio consumado, siendo mayor el riesgo de suicidio en el primer año de la presencia de ideación suicida. Los datos reportados, tanto a nivel mundial, como nacional, reflejan una tendencia al aumento en la prevalencia de conductas suicidas, convirtiéndose, por tanto, en un problema de salud pública.Objetivo: conocer los hallazgos relacionados con la ideación suicida en población colombiana a partir del análisis de los artículos publicados durante el periodo comprendido entre el 2010 y el 2016, recuperados a través de los sistemas de información Redalyc, ScienceDirect, Medline, Mediclatina y Scopus.Método: la búsqueda se realizó a partir de los resúmenes encontrados, vinculando las áreas de conocimiento de psicología, medicina y ciencias sociales.Resultados: fueron hallados en total 22 artículos en los que se estudió la ideación suicida de manera independiente o relacionándola con otras variables, predominando las investigaciones de carácter cuantitativo de tipo descriptivo o correlacional, abordadas, principalmente, desde el campo de la psicología clínica, y cuyo grupo poblacional estuvo enmarcado en adolescentes y adultos jóvenes.Conclusión: se identificó un marcado interés académico e investigativo en el diagnóstico clínico del componente cognitivo del suicidio, siendo evidente el déficit en investigaciones relacionadas con la prevención o intervención de este factor de riesgo, a pesar de considerarse como un problema de salud pública.
Tratamiento de aguas residuales domesticas mediante humedales subsuperficiales con macrófita Alocasia macrorrhizos (orejas de elefante) en la urbanización los tulipanes –Chosica, Lima
Authors: Castro Sarco Diana Gloria , Cruz Paredes Yobana Elsa , Florez Mamani Michael Edgard
Published: August 2018

El objetivo de este artículo es evaluar la eficiencia de la macrófita alocacia macrorrhizos (orejas de elefante) en un humedal artificial subsuperficial de flujo horizontal para la remoción de los parámetros físicoquímicos y microbiológicos, para el riego de cultivos agrícolas. Utilizando el método de aforo de caudal, método de tubos múltiples y análisis físico químico, y la prueba de T-Student. Para el diseño del humedal se empleó 8 macrófitas de alocasia, se manejó un tanque a escala piloto con 16 litros, donde posteriormente se almaceno el agua a tratar durante un periodo de retención de 3 días, consecutivamente con el monitoreo de un mes. La eficiencia del uso del humedal subsuperficial con la macrófita consiguió el 60.72% de remoción de parámetros microbiológicos (coliformes totales, coliformes termotolerantes y e.coli),  fisicoquímicos (pH, temperatura, turbiedad, conductividad eléctrica, oxígeno disuelto, solidos totales, DBO5 , DQO, fosfato) y organolépticos (olor, color, sabor) del agua residual, por ello, se confirma que la eficiencia de las macrófitas como parte del tratamiento de agua residual es viable a un nivel ambiental, económico y ostenta ventajas atractivas para el apoyo de la conservación del ambiente ya que no requieren grandes insumos de energía o máquina para su operación.
Bir Üniversite Acil Servisine Başvuran Geriatrik Hastaların Özellikleri
Authors: Bedel Cihan , Tomruk Önder
Published: August 2018

Amaç: Yaşlılık insan yaşamının geri dönüşümsüz bir
süreci olarak kabul edilmektedir. Acil servise başvuran geriatrik
hastalıkların özelliklerinin bilinmesi doğru tanı ve acil tedavi yaklaşımında
yol gösterici olabilir. Çalışmamızın amacı genel olarak geriatrik hasta
başvurularının verilerini analiz etmek, elde edilen sonuçlarla vermekte olduğumuz
hizmetin ileriye yönelik yapılanmasında neler yapılabileceğini planlamaktır.

Metod: Ocak 2012- Ocak 2013 tarihleri arasında
başvuran 65 yaş ve üzeri 2101 hastanın kayıtları retrospektif olarak incelendi.
Kayıtlardan hastaların yaş, cinsiyet, başvuru şekli, başvuru saati,
şikayetleri, şikayetlerinin dağılımı, ön tanıları, taburculuk ve yatış
oranları, yatırıldığı bölümlere ait veriler incelenmiştir.

Sonuç: Toplam hasta sayısı 14754, 65 yaş ve üzeri
hasta sayısı 2101 (%14.2) olarak bulunmuştur (1111 erkek, (%52.9); 990 kadın,(
%47.1)). Hastalarımızın yaş aralığı; 65-74 yaş %43.8, 75-84 yaş %45.4, 85
yaş üzeri ise %10.8 olarak saptan­mıştır. Hastaların %52.4’ü özel araç,
%40.6’sı ambulans ile başvurmuştur. Çalışılan
hastaların  %15.8’ine yatış yapılmış, %2.3’ü sevk olmuştur. 26 hasta
da exitus olmuştur. Hastaneye yatış yapılan 331 hastadan  %28.7’si
yoğun bakıma yatışı yapılmıştır. En çok yatış yapılan bölümler 106 hasta ile
dahiliye ve 88 hasta ile kardiyolojidir. Hastaneye başvuru şikayetlerinin
yüzdeleri karın ağrısı %15.7, nefes darlığı %15.7, göğüs ağrısı %11.2’dir. En
sık bulunan hastalıklar sırasıyla %20.2 ile kardiyovasküler hastalıklar, %14.3
onkolojik hastalıklar, %11.1 solunum sistemi hastalıkları, %10.1
gastroenterolojik hastalıklar olarak saptanmıştır. Hastaların ön tanıları
incelendiğinde %15.4 onkolojik hastalık ve acilleri,  %8.9 kalp
yetmezliği, % 6.9 KOAH ve astım olarak saptanmıştır.

Tartışma: Artan yaşlı nüfusla
birlikte acil servislerin yaşlı hastalar tara­fından kullanımı artmaktadır.
Değişik çalışmalarda yaşlı hastaların farklı nedenlerle acil servise başvurduğu
görülmektedir. Yapılan çalışmalarla hastanelerin kendi acil servislerine
başvuran yaşlı has­taların oranının ve sık görülen hastalıkların belirlemesi bu
hastaların takip edileceği özel bölümlerin düzenlenmesine yardımcı
olur. Bu sayede daha hızlı ve doğru tanı konularak tekrarlayan başvuruları
azalta­cağını düşünmekteyiz.
Bilgisayarlı tomografide geriatrik hastalarda adrenal insidentaloma prevalansı
Authors: KULALI Fatma , SEMİZ-OYSU Aslıhan , BASAT Sema , KULALI Şafak Fırat , BÜKTE Yaşar
Published: August 2018

Amaç:
Amacımız, bilgisayarlı tomografi (BT) tetkiklerinde, 65 yaş ve üstü hastalarda
insidental saptanan adrenal lezyonların prevalansını araştırmaktır.Gereç-Yöntem:
Hastanemizde, Ocak 2013 ve Nisan 2014 tarihleri arasında, üst batın BT
tetkikleri yapılmış ardışık 903 hasta tekrar değerlendirildi. Bilinen kanser
öyküsü olan, adrenal patolojilere yönelik tetkik yapılan ve 65 yaş altı
hastalar çalışma dışı bırakıldı. Çalışma grubunu, 178 hasta oluşturdu. Çalışma
grubunda yer alan hastaların, BT tetkikleri incelendi. Adrenal lezyon varlığı,
varsa lezyon en uzun çapı ve görüntüleme özellikleri bir radyolog tarafından
kaydedildi. Lezyonların radyolojik bulgularına göre ön tanıları yapıldı.
Malignite özellikleri olanlar, çalışma dışı bırakıldı. BT’ de, adrenal
insidentaloma saptanma oranı hesaplandı. Bulgular:
BT tetkikleri incelenen, 93’ü kadın, 85’i erkek olan, 65 yaş ve üzeri 178 hasta
çalışma grubunu oluşturdu. Bu hastaların, 86’sında adrenal lezyon saptanırken
92’sinde adrenal glandlar doğaldı. Olguların ikisinde malignite ile uyumlu
görünüm saptandığı için insidentaloma grubundan çıkarıldı. İnsidental adrenal
lezyon saptanan 84 olgunun, 20’sinde diffüz adrenal hiperplazi, 53’ünde adenom,
11’inde myelolipom ile uyumlu radyolojik özellikler izlendi. Adrenal
insidentaloma prevalansı  %47,2 olarak
saptandı.

Sonuç:
Çalışmamızda, BT’de geriatrik hastalarda adrenal insidentaloma prevalansı %47,2
bulunmuş olup küçümsenmeyecek derecededir. Günümüzde görüntüleme yöntemlerinin
daha çok kullanılması ile sık saptanan adrenal insidentalomaların malignite
ekartasyonu yapıldıktan sonra fonksiyonel açıdan değerlendirilmesi gereklidir.
Endo F2 v1
Authors: Gibson Mike
Published: August 2018

Endo F2 cleaves Asparagine-linked high mannose or biantennary oligosaccharides. It cleaves between the two N-acetylglucosamine residues in the diacetylchitobiose core of the oligosaccharide, generating a truncated sugar molecule with one N-acetylglucosamine residue remaining on the asparagine. In contrast, PNGase F removes the oligosaccharide intact.
Kısıtlanmış Boltzmann Makinesi Ve Farklı Sınıflandırıcılarla Oluşturulan Sınıflandırma İş Hatlarının Başarımının Değerlendirilmesi
Authors: KARASULU Bahadir
Published: August 2018

Literatürdeki birçok sınıflandırıcı yöntemi en yüksek sınıflandırma
doğruluğuna ulaşılması için kullanılmaktadır. Kısıtlanmış Boltzmann makinesi
danışmansız öğrenmenin yapıldığı bir yapay sinir ağı olmasının yanı sıra,
öznitelik elde etmekte kullanılan öğrenen bir bileşen olarak önem kazanmıştır.
Çalışmamızda Bernoulli tipli kısıtlanmış Boltzmann makinesi ve farklı
sınıflandırıcılar kullanılarak oluşturulan beş farklı iş hattının başarımları
kıyaslanmaktadır. Bu iş hatlarında sırasıyla lojistik regresyon, karar ağacı,
Gauss saf Bayes, Ada Boost ve rasgele orman sınıflandırıcı kullanılmıştır.
Sınıflandırma sonucu değişiklikleri, bu sınıflandırıcıların elde ettiği tek
başına sınıflandırma sonuçlarına kıyasla iş hatları kullanılarak
gözlemlenmiştir. Deneysel sonuçlar, MNIST el yazısı rakam tanıma veri kümesi
kullanılarak elde edilmiştir. Bu deneylerde kısıtlanmış Boltzmann makinesinin
üstün parametrelerinin iki farklı düzeni kullanılmıştır. Bu sonuçlara göre, tek
başına sınıflandırıcının sınıflandırma doğruluğunun deneylerdeki iş hatları
kullanımı sayesinde daha iyi hale geldiği görülmüştür. En yüksek başarım %97,19'luk
bir sınıflandırma başarı oranıyla elde edilmiştir. Önerilen iş hattı tasarımını
kullanan modeller ilgili bireysel sınıflandırıcı ortalama başarımlarını en az %1
ilâ en çok %33 arasında iyileştirmiştir. Makalede tartışmaya da yer
verilmektedir.
Yapay Sinir Ağları ve Zaman Serileri Yöntemi ile Bir Endüstri Alanının (İvedik OSB) Elektrik Enerjisi İhtiyaç Tahmini
Authors: Özden Semih , Öztürk Ali
Published: August 2018

Özel firmalara enerji sağlayan firmalar veya
işletmeler için enerji tüketiminin tahmini ve ihtiyaç planlaması çok kritiktir.
Özellikle endüstri bölgelerindeki enerji ihtiyacı ev kullanıcılarının
ihtiyacından daha yüksektir, bundan dolayı enerji ihtiyacının doğru tahminini
gerektirir. Bu çalışmada, zaman serileri ve yapay sinir ağları olmak üzere iki
farklı yaklaşım kullanılarak Türkiye’deki bir endüstri bölgesi için enerji
ihtiyaç tahmini üzerinde çalışılmış ve sonuçlar test edilmiştir. Daha önceki
çalışmalardan farklı olarak, kısıtlı veri ile kısa dönem tahmini için basit bir
model geliştirilmiştir. Model, giriş parametresi olarak geçmiş günlere ait
tüketim verileri ve sıcaklığı içermektedir. Sıcaklık verisi, endüstri
bölgelerinde ısıtma amaçlı enerji tüketiminde kullanıldığı için anahtar rol
oynamaktadır. Zaman serileri yaklaşımında sadece geçmişe ait enerji tüketim
verileri kullanılmıştır. Her iki yaklaşım enerji ihtiyaç tahmininde
kullanılmış, sonuçlar tartışılmış ve karşılaştırılmıştır.
Modelling and control of permanent magnet synchronous generator based on three level NPC using fuzzy PI
Authors: GENCER Altan
Published: August 2018

Recently, the permanent magnet synchronous generator (PMSG) has been gained attention by wind turbine (WT) manufactures due to advance of control system and power electronics. The permanent magnet synchronous generator based on three level neutral point control (NPC) system using fuzzy logic control proportional integral (FLC PI) is proposed in this study. The NPC systems of DC link are implemented more easily than two level systems. The NPC systems provide better harmonic reduction than conventional two level voltage source converters. The control strategies of the NPC systems reduce semiconductor losses. The proposed system can be implemented to the multi-level converters above three-level. The proposed system is developed using the steady state technique. The performance of the PMSG system under variation operation condition is investigated in this study and the performances of the PMSG based on three level NPC using FLC PI are analyzed. The validity of the proposed system is implemented and verified in the MATLAB/Simulink using three-level insulated gate bipolar transistor (IGBT) converter.
SOCIAL INTEGRATION OF INTERNATIONAL MIGRANTS IN PRIMORSKY KRAY: PROBLEMS AND PERSPECTIVES
Authors: AMIRKHANIAN A. G. , BORODKINA O. I.
Published: August 2018

Primorsky kray is among most developed regions of Russia’s Far  East. However, the region is depopulating as mortality rate exceeds  birth rate and due to out-migration of a local population. Labor  migration partly compensates labor deficiency in the local labor  market. Integration of international migrants becomes a vital issue.  The purpose of this paper is to identify factors that facilitate or  hamper international migrants' integration to a local labor market,  medical care and institutions of cultural integration of Primorski kray,  as well as practices used by migrants to overcome the  barriers. The research is based on statistical data and data from prior published research as well as on the results from 12  expert interviews. The experts are specialized in the field of  migration in Primorsky krai. International migrants encounter  barriers when obtaining the legal work permissions and with a  limited access to the medical care services. To overcome the  barriers, migrants use a wide range of resources including services  of intermediary firms specialized on migrants from the APEC  countries as well as NGO services. To reduce social risks related to  labor migration and to enhance migrants’ social integration, a  system of the organized recruitment of labor migrants in their  countries of origin is needed for their consequent employment in  Primorsky kray. In addition, to facilitate migrants’ ethno-cultural and  linguistic adaptation, further development of civic organizations is  needed.
CHINA AND RUSSIA IN THE CONDITIONS OF NONRADIATION CHALLENGES AND THREATS OF NATIONAL SECURITY
Authors: Yan CHANG
Published: August 2018

In this article, the author considers non-traditional challenges and  threats to national security to the People's Republic of China and the  Russian Federation. The author notes that the political and economic potential of these two countries is steadily increasing. The  countries have solved a complex border issue, effectively cooperate  within the framework of the SCO. At the same time, despite the warming of the general political climate in the Northeast Asia  region, China-Russia security, as well as international security in  general, continue to be threatened by various challenges of  nontraditional security. To traditional security, the author refers to  the state, political and military security of the country.  Unconventional security exists in relation to traditional security, and  includes, first of all, the issues of economy, culture, education, science and technology, the environment, as well as  terrorism; environmental pollution; the spread of drugs and the  spread of infectious diseases. The threats to unconventional security  are peculiarities of non-state, non-state, transnational, unexpected and unpredictable and are located to rapid changes and  from local ones can quickly turn into world challenges. That is why  China and Russia need cooperation to prevent and stop  unconventional challenges and threats to national security.
WILL BLOGERS REPLACE JOURNALISTS? INSTITUTIONAL AND NON-INSTITUTIONAL ACTORS AT THE INTERSECTION OF MEDIA AND NETWORK SPACES
Authors: GAVRA D. P. , DEKALOV V. V.
Published: August 2018

In the paper, we consider the relationship between institutionalizedand non-institutionalized actors of media space within the framework  of communicative capitalism (J. Dean). We develop this  concept in the context of attention economy and new ways of digital  capitalization. Internet user's attention is attracted, enclosed in particular Web segments, and converted into money by these  segments’ owners and holders. So, new digital subjects  with  significant recourses and capabilities occur. Among them: traffic  monopolists, network elites, communicative capitalists. The  convergence of media- and networked spaces of social system  complicates relation configurations between subjects in both spaces.  Media relations are digitalized. Networked relations are mediated. On the area of these spaces’ intersection, different actors operate. They  are digital subjects, Internet users, media and journalists, media  audiences. Their communicative strategies and practices transform  and intertwine each other. In the paper, we highlight two situations. The first situation: when a journalist creates her or his  own network brand and tries to attract a new audience in her or his  Web segment. She or he faces with distrust and the desire of  Internet users to overturn the established symbolic hierarchies. The  second situation: when a digital actor tries to get rents from the  media space. She or he competes for the media audience and backs  up her or his independent status. Both situations give rise to a  number of opportunities and number of threats. Both digital actors  and journalists are influenced with algorithm biasing and post-truth  dissemination. The latter is aggravated with political actors’  participating and media and political subsystems converging.
Effect of renal dysfunction on the quality of life indicators associated with pain and general discomfort in arterial hypertension
Authors: Yakuhnaya E V , Solyanik E V , Borodina I A , Egorova M B
Published: August 2018

Aim. To study the severity of patient’s pain and general discomfort by visual analogue scale in hypertension and to determine the possible dependence of this parameter on the degree of decreased glomerular filtration rate reflecting the stage of chronic kidney disease.

Methods. The study included patients diagnosed with essential hypertension and admitted to internal medicine department of FSBIH «Far Eastern District Medical Center» of FBMA of Russia, who agreed to participate in the study. Inclusion criterion was the verified diagnosis of hypertension stage 2-3, and exclusion criteria were decreased glomerular filtration rate

Results. In 8 (11.7%) patients, glomerular filtration rate was high and optimal, in 27 (38.2%) surveyed patients a slight decrease was revealed. A decrease of glomerular filtration rate

Conclusion. The combination of hypertension and severe renal dysfunction reduces the overall index reflecting the change in the quality of life by almost a quarter; the study of the quality of life parameters by visual analogue scale can be used in a comprehensive assessment of the effectiveness of medical measures improving the quality of medical care for patients with the combination of arterial hypertension and chronic kidney disease.
Prediction of risk of arterial hypertension among female adolescents born preterm
Authors: Abrarov R A
Published: August 2018

Aim. Development of an algorithm for predicting the risk of arterial hypertension among female adolescents in Bashkortostan Republic who were born preterm.

Methods. The analysis of risk factors of cardiovascular diseases was performed among 95 female adolescents with arterial hypertension and 120 female adolescents with normal blood pressure aged 16 years who were born preterm. Blood pressure was measured depending on the percentile distribution of height according to Russian guidelines on prevention of cardiovascular diseases among children and adolescents.

Results. Based on Wald's method, predictive algorithm of risk of arterial hypertension and computer soft on its bases were developed for female adolescents of Bashkortostan Republic born preterm. Prognostic indicators, which demonstrated diagnostic index ≥2,0 and informativeness coefficient ≥0,25 were selected. If the total score of diagnostic indices is +13 points or more, then the conclusion should be made that there is 95% probability of arterial hypertension development. Total score of +8 to +12 is evident for 75% probability of arterial hypertension development. The developed soft makes it possible for female adolescents born preterm to pass comprehensive test and to get a conclusion about the probability of arterial hypertension development and scientifically based personalized recommendations for its prevention.

Conclusion. The developed prognostic algorithm will promote early diagnosis of arterial hypertension among female adolescents in Bashkortostan Republic who were born preterm; it allows defining adolescent groups at risk of this pathology aimed at early preventive measures.
Light and electron-microscopic study of epithelium covering free gingiva at various stages of chronic gingivitis in patients with β-thalassemia major
Authors: Gasymov E K , Shadlinskaya R V , Israfilova S A
Published: August 2018

Aim. Study of the nature and severity of reorganization of the structural elements of gingival epithelium in remission and exacerbation of chronic catarrhal sclerosing gingivitis in patients with β-thalassemia major at the light-microscopic and ultrastructural levels. Methods. From araldite-epon blocks of gingival biopsy specimens taken from 18 patients with β-thalassemia major, the semithin (1-2 μm) and ultrathin (35-70 nm) sections were obtained by means of ultramicrotome. Semi-thin sections were stained by trichrome. Viewing of stained and unstainted ultrathin sections was performed on an electron microscope at an accelerating voltage of 80-120 kV. Results. The increase of ferritin molecules in the intercellular space and in cytoplasm of all cellular elements (except for neutrophils) of the epithelial coverage of the gingiva, as well as the presence of siderophages in the exudative phase demonstrate that one of the main causes of exacerbation of chronic catarrhal sclerosing gingivitis in patients with β-thalassemia major is an increase of congestion of their body with iron-containing elements. The widened slit-like spaces of various shapes and sizes existing in gingival epithelium especially in the acute stage, should be considered as a sign of intercellular edema - spongiosa, and not acantholysis. Disruption of tonofilament-desmosomal complexes of gingival epithelial cells and increased accumulation of glycogen granules in developed hypoxia can be considered the main factors involved in altering the cytodifferentiation of gingival epitheliocytes in the exudative phase of chronic catarrhal sclerosing gingivitis that results in occuring in stratum corneum of light cells without any signs of keratinization, as well as the absence of an epithelial barrier. Conclusion. Identification of molecular mechanisms of disorders of neutrophil and epithelial barriers of gingival mucous membrane can be used in the diagnosis and development of new principles of treatment of inflammatory processes in patients with β-thalassemia major.
Factors associated with rectal tumor and their influence on tumor regression grade after neoadjuvant chemoradiotherapy
Authors: Aliyarov Yu R
Published: August 2018

Aim. To determine relation between localization, grade of invasion and differentiation in rectal tumor and tumor regression grade after neoadjuvant chemoradiation therapy.

Methods. 88 patients with local advanced rectal cancer (Т2-4N0-2М0) were analyzed: 46 females and 42 males. The average age was 52.4±1.4 years. All patients underwent neoadjuvant chemoradiotherapy. In all groups regardless of tumor localization patients with stage T3 and moderate differentiation grade predominated.

Results. Complete pathological tumor response of grade 4 (TRG4) was revealed in 13 (14.7%) patients, grade 3 (TRG3) in 34 (38.6%) patients, low treatment effect (tumor response grade 2, TRG2) was registered in 26 (29.5%) patients, and lack of treatment effect (grade 1, TRG1) in 15 (17.2%) patients. Analysis of the data from patients with complete or nearly complete tumor regression (grade 3 and 4) demonstrated that such effect of neoadjuvant treatment was most often observed in patients with tumor localized in rectal lower ampulla (58.6%). Among patients with moderately differentiated adenocarcinomas, patients with tumor response of grade 3 and 4 predominated: 28 (56%) patients. According to invasion grade, in all groups patients with therapeutic response grade 3 and 4 prevailed, but most prominently - in groups of patients with stage T4a and T4b - 58.9%.

Conclusion. The closer to anus tumor is located, the more significant effect neoadjuvant therapy has; moderate tumor differentiation grade can be considered as a relative predictive factor of tumor regression on preoperative chemoradiation therapy.
Age-related features of activity of free radical oxidation in erythrocyte membranes and blood plasma in postinfarction cardiosclerosis in rats
Authors: Rebrova T Yu , Afanas’ev S A
Published: August 2018

Aim. To determine the presence of lipid and protein peroxidation products in erythrocyte membranes and blood plasma in rats of different ages in an intact state and with developed postinfarction cardiosclerosis.

Methods. In rats aged 4, 12, 24 months postinfarction cardiosclerosis was modeled by coronary occlusion. In blood plasma and erythrocyte membranes, products reacting with thiobarbituric acid and carbonyl derivatives of protein amino acid residues were determined.

Results. In erythrocyte membranes of intact animals aged 12 months, a decrease of the content of thiobarbituric acid-reacting products was revealed in comparison with 4 month-old animals, and in 24 months-old animals the index significantly exceeded the values of young subjects. In the blood plasma of intact animals aged 12 and 24 months, an increased content of thiobarbituric acid-reacting products with respect to rats aged 4 months was revealed. In postinfarction cardiosclerosis, an increase in the accumulation of thiobarbituric acid-reacting products was observed in erythrocyte membranes of 4 and 24 months-old animals. In blood plasma, an increase of this parameter was noted only in the group of 4 months-old animals with postinfarction cardiosclerosis. In erythrocyte membranes of intact rats of all age groups, no differences in the level of carbonyl derivatives of protein amino acid residues were observed, and in blood plasma it significantly increased with age. In 4 and 12 months-old animals with postinfarction cardiosclerosis, significant increase of carbonyl derivatives of protein amino acid residues was mostly pronounced in erythrocyte membranes. In 24 months-old animals with postinfarction cardiosclerosis, this parameter in the membranes and blood plasma was stable.

Conclusion. The intensity of processes of cell membrane and blood lipid peroxidation has pronounced age-dependent features that persist in postinfarction cardiosclerosis; proteins of erythrocyte membranes of intact animals are subject to peroxide modification to a lesser degree than blood plasma proteins; in postinfarction cardiosclerosis formation in 4 and 12 months-old animals, carbonyl derivatives of protein amino acid residues are more intensively accumulated in erythrocyte membranes compared to blood plasma.
Diagnostic and prognostic value of assessment of soluble adhesion molecules sICAM-1 and sVCAM-1 in septic patients
Authors: Moskalets O V
Published: August 2018

The review is devoted to the assessment of use of cell adhesion molecules including intercellular adhesion molecule type 1 (ICAM-1) and vascular cell adhesion molecule type 1 (VCAM-1) as additional laboratory markers for severity assessment and as predictors of outcome in septic patients. One of the very important pathogenetic components of this state is known to be endothelium activation replaced by its dysfunction. The level of expression of these molecules on endothelial cell membrane affects leukocyte migration from the vessels to surrounding tissues. Besides, a number of cell adhesion molecules are expressed on immunocompetent cells that influences the development of immune response (both innate and acquired). The main characteristics of ICAM-1 and VCAM-1 are presented, including the possibility of soluble forms formation (sICAM-1, sVCAM-1) due to shedding of cell membrane induced by proteolytic enzymes. The results of literature analysis demonstrate that in sepsis the serum content of sICAM-1 and sVCAM-1 is significantly higher than in healthy subjects. In most cases their level is higher than in patients with other critical states (such as severe infectious inflammatory processes, myocardial infarction, stroke, burns, etc.) that according to some authors allows their using for differential diagnosis of sepsis and other critical states. There is no consensus on correlation with disease severity (sepsis, severe sepsis, septic shock), presence of multiple organ failure and its prediction, and lethal outcomes. Results inconsistency most probably can be explained by differences in study design. Nevertheless, continuing studies in this direction is considered perspective.
«Grey zone» of heart failure
Authors: Galin P Yu , Kulbaisova S A , Erov N
Published: August 2018

The review is devoted to modern understanding of heart failure with mid-range ejection fraction. The formation of the paradigm of «two phenotypes» of heart failure began around the end of the last century. As a result of a number of large epidemiological studies on heart failure with preserved ejection fraction, so-called «grey zone» of ejection fraction values was formed in the range of about 40-50%. This situation arose because of the lack of clearly established level of normal ejection fraction and underlines imperfection of this parameter as the only classification criterion. But no more convenient «tool» for research work was offered. In the past decade, «grey zone» of heart failure has been actively explored by clinical epidemiologists and clinicians. Should we classify these patients as one of the existing phenotypes of heart failure or present them as a new, separate phenotype? Both the first and second decisions require information about the population «portrait» of subgroup, about their response to treatment, and presumptive pathophysiological mechanisms of heart failure. In 2016 European society of cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure, heart failure with mid-range ejection fraction was determined as a separate subgroup to stimulate the search for such data. At the moment mid-range ejection fraction is known to be recorded in about 10-20% of patients with heart failure. They have substantial comorbidities as patients with preserved ejection fraction but the prevalence of ischemic heart disease in this subgroup makes it similar to heart failure with reduced ejection fraction. The response to treatment with beta-blockers and aldosterone antagonists is similar to that of heart failure with reduced ejection fraction. It is important that the mortality rates in all three groups of patients are approximately the same. This circumstance underlines the importance of further searche. Perhaps the research of «grey zone» of the syndrome will help to better understand pathophysiology of the existing heart failure phenotypes and confirm the validity of their identification based on ejection fraction.
The role of complement system and other inflammatory factors in the development of age-related macular degeneration
Authors: Abdulaeva E A
Published: August 2018

The article is a review of literature on the role of complement system and inflammatory factors in the development of age-related macular degeneration. The review uses materials of domestic and foreign researchers. The clinical characteristics of age-related macular degeneration are presented, the role of genetic factors, complement factors, biomarkers of inflammation and alternative pathway of complement activation in the pathogenesis and risk of age-related macular degeneration is determined. Age-related macular degeneration is a chronic progressive multifactorial disease that affects macular area of the retina and is the main cause of loss of central vision in patients of older age group. The most important genetic factors are chromosome 1 (1q32) including complement factor H and complement factor H related genes and chromosome 10 (10q31). Variants associated with a moderate effect on developmental risk were identified in C3, complement factor I and complement factor B genes. In the pathogenesis of age-related macular degeneration, the key role is played by the damaged regulation of the alternative complement pathway. Single nucleotide polymorphisms in complement genes that affect the risk of development of age-related macular degeneration are predominantly involved in the alternative pathway of activation of the complement system. In pathomorphological studies, the initial localization of the pathological process of this pathology was established to be a complex of retinal pigment epithelium, Bruch’s membrane, and choriocapillaries followed by loss of photoreceptor function. The review of studies of systemic inflammatory biomarkers, cytokines, vascular endothelial growth factors in peripheral blood, blood serum, aqueous humour at various stages and forms of age-related macular degeneration is presented.
Morbidity dynamics of type 1 diabetes mellitus in different administrative territorial units of Azerbaijan Republic in 2012-2016
Authors: Alieva I Dzh
Published: August 2018

Aim. To assess the dynamics of population’s morbidity of type 1 diabetes in different autonomous territorial units of Azerbaijan Republic.

Methods. The unit of observation was a case of type 1 diabetes newly diagnosed during the calendar year. For each administrative territorial unit of Azerbaijan Republic based on the data about quantity of patients with type 1 diabetes and population, morbidity rate per 100 000 of average annual population and average error for calendar years were calculated.

Results. At the beginning of observation (2012) morbidity rate of type 1 diabetes among Azerbaijan population was 54.5±0.76 per 100 000. In different administrative territorial units this indicator ranged between 2.0±1.41 and 294.8±12.0 per 100 000. Relatively low rate of type 1 diabetes was identified in Mingachevir town (2.0±1.41), Masalli (6.1±1.7), Jalilabad (5.8±1.68), Imishli (5.7±2.17), Sheki (4.5±2.17), Gusar (2.2±1.52) regions and Absheron (5.0±1.57 per 100 000). The highest morbidity rate in 2012 was observed in Shamkir (294.8±12.0), Khachmaz (278.7±12.82) and Sabirabad (236.6±11.9 per 100 000). The main trend of difference is a linear decrease of the morbidity rate, which is well explained by linear regression equation (Y=-9.078х+61.1; R2=0.95). In Azerbaijan the average morbidity rate of type 1 diabetes in 2012-2016 was 33.2±0.58 per 100 000, there are administrative territorial units with low (60 per 100 000 in Shirvan city, Sabirabad, Shamkir, Khachmaz districts).

Conclusion. Morbidity rate of type 1 diabetes was different in different calendar years, ratios of the highest and lowest annual morbidity rate in Azerbaijan (3.5) and in separate administrative territorial units (4.2 in Baku, 23.9 in Ganja, 90.0 in Mingechevir, etc.) are different.
Mobil Tip Unikondiler Diz Artroplastisi Uygulanan Hastalarda Patellofemoral Ağrı
Authors: ERÇİN Ersin , ÇELEN Kurmay , KIZILKAYA Cemal , ÖNEŞ Halil Nadir , KURAL Cemal
Published: August 2018

Özet

Amaç

Çalışmamızın amacı kliniğimizde mobil
unikondiler diz artroplastisi uyguladığımız hastaların ameliyat önceki
dönemdeki patellofemoral ağrı durumlarını ameliyat sonrası dönemle kıyaslamak
ve sonuçlarını değerlendirmektir.

Gereç ve Yöntem

Yirmiiki unikondiler diz artroplastisi
uyguladığımız hastayı çalışmaya dahil ettik. Ameliyat öncesi tüm hastalar
ayakta ön-arka, lateral grafileri ve bacak uzunluk grafileri ile
değerlendirildi. Tüm hastalar aynı cerrahi yöntem kullanılarak ameliyat edildi.
Tüm hastalara aynı tip protez kullanıldı (Mobil insertli, Corin,  UK). Hastaların operasyon öncesinde ve 3 ve
6.  ay kontrollerinde değerlendirilmelerinde
Womac diz skoru, Kujala patellofemoral skoru ve Vas skoru  kullanıldı. Preopertaif diz skorları
postoperatif skorlar ile istatistiksel olarak karşılaştırıldı.

Bulgular

Hastaların
ameliyat öncesi ortalama WOMAC, VAS ve Kuaja patellofemoral skorlarında
ameliyat sonrası ile kıyaslandığında belirgin olarak azalma tespit edildi
(p<0.05).  Üç  hastada takiplerde komplikasyon saptandı (
(%13.6). Kompliksayon nedenleri; mobil insert luksasyonu ve metalozis,

artan  patellofemoral ağrı ve diğer kompartmanlarda
gelişen artroz, ve minör travma sonrası (basit düşme) gelişen diz iç yan bağ
rüptürü idi.

Sonuç

UKDA da başarıyı etkileyen en
önemli faktörler cerrahi teknik özellikle ameliyat sırasında kinematik
değerlendirmenin iyi yapılması ve hasta seçimidir. Özellikle patellofemoral
kompartman durumu hem grafiler hemde klinik bulgular eşliğinde
değerlendirilmelidir. Patellofemoral ağrı tek başına UKDA için bir
kontrendikasyon olarak değerlendirilmemeli ancak bu hastalar için ameliyat
kararı verirken seçici davranılmalıdır. 
Pattellofemoral semptomlar ve ağrı postop erken dönemde agreve olabilir,
kesin değerlendirmeler için en az 6 ay beklenmeli erken revizyon kararı
verilmemelidir. UKDA yapılan hastaların iç yan bağ rüptürüne karşı hassas
olduğu ve minör travmalarla bile iç yan bağ rüptürü gelişebileceğini akılda
tıutmalıyız.
Factors Affecting Job Satisfaction, Motivation and Turnover Rate of Medical Promotion Officer (MPO) in Pharmaceutical Industry: A Study Based in Khulna City
Authors: Alam Shahi Md. Tanvir
Published: August 2018

Due  to  the  fast  growing  of  the  pharmaceutical  sector, the  demand  of  medicine  is  mostly  fulfilled  by  the  local  industry. In  the  local  market, the  medicines  are  distributed  and  marketed  by  the  Medical  Promotion  Officers (MPOs). The  main objective of the study  is to find out the  job satisfaction, motivation  and  turnover  factors  of  MPOs.  Along with different reports, it is conducted direct field survey to the 40 (forty) MPOs of different pharmaceutical companies in the Khulna City. Likert  Scale, based  on  five  points, is  used for  data collecting. It  is  found  that  the  most  of  the  MPOs  are  not  satisfied  with  their  jobs  and  for  this  they  are  not  motivated  and  for  this  their  turnover  tendency  is  high. The  MPOs  are  dissatisfied  with  their  job  security, social  status, working  load, visit  to  retailers’  shop, sales  target, no  room  for  family, not  getting  the  retirement  benefit  and  not  getting  the  family  insurance  support. And  finally  there  is  given  suggestion  by  the  force  field  analysis  model  for  removing  the  restraining/negative  forces factors  for  reducing  the  turnover  rate. Also  there  is  also  mentioned  the  driving/positive  forces  factors  for  omitting  the  turnover  rate.
Finisterra Annual Lecture: Placing gender in geography, directions, challenges, and opportunities
Authors: Monk Janice
Published: August 2018

Since the emergence of interest in gender in the late 20th century its significance has become widely, though unevenly, included in research, teaching, and applied work in human geography and related social sciences. This Finisterra Annual Lecture reviews aspects of engagement internationally – where and how work has developed, themes addressed, methods applied, and approaches to dissemination. It notes advances made and some continuing challenges.
Professor Doutor Ilídio do Amaral
Authors: Moreira Adriano
Published: August 2018

PROFESSOR DOUTOR ILÍDIO DO AMARAL
Using an Adaptive Environmental Management Framework to Regulate the Unconventional Gas Industry: A Case Study of Queensland, Australia
Authors: Coles Neil A.
Published: August 2018

Australia has just witnessed one of the longest resources booms in the country's history. But who benefited? Was the rapid expansion managed in such a way to protect affected communities, ecosystems, and water resources? And what legislative approach has delivered the best outcome? Unconventional gas has been touted as the great saviour in terms of energy, providing a transitional resource that will enable the global economy to shift from a non‐renewal hydrocarbon‐based economy to renewable energy sources. The development of the unconventional gas industry in the state of Queensland has created opportunities for the significant capital investment, job creation, and the beginnings of a massive liquefied natural gas export industry within the State. During the period of expansive development, water and environmental legislation was often at odds with both the industry and the community. Successive governments grappled with the best approach for capturing community concerns and supporting the development of a new industry that promised significant benefits to the State through jobs, taxes, and royalties. This paper evaluates the adaptive environmental management approach adopted by Queensland to manage the new unconventional gas industry and whether this has been successful.
OPTIMIZATION OF OCCLUSAL SURFACE MODELING FOR FULL CERAMIC RESTORATIONS
Authors: Шатров И. , Shatrov I. , Жолудев С. , Zholudev S.
Published: August 2018

Functional  dental  restorations – an  impor tant aspect  of the  health  and  life quality. the most accurate  way to create  restoration is wax up. it is problem  to save this shape  in ceramic restoration. this article  describes  how to repeat  the shape  of wax up in the final ceramic restoration.

 
IMPROVED METHOD OF RETENTION AFTER ORTHODONTIC TREATMENT DEEP OVERBITE
Authors: Лазарева О. , Lazreva O. , Бимбас Е. , Bimbas E.
Published: August 2018

It is necessary to counteract mechanisms of anomaly development for preservation stability of results orthodontic treatment deep overbite. in article are presented the offered improvements of fixed retention application after orthodontic treatment deep overbite.

 
ESPECIALLY ORGANIZATIONS OF INDEPENDENT WORK OF STUDENTS AT SPECIALIZED DENTAL CHAIR IN MODERN CONDITIONS
Authors: Жолудев С. , Zholudev S. , Карасева В. , Karasevа V. , Стрижаков В. , Strizhakov V.
Published: August 2018

This article the difficulties of forming the organization skills of dental students at the faculties specialized departments, discusses possible solutions.

 
THE REPORTING ON THE RUSSIAN CONGRESS «DENTISTS BIG URAL»/
Authors: Жолудев С. , Zholudev S.
Published: August 2018

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STRENGTH FEATURES OF ADHESIVE BOND ON AXIAL COMPRESSION
Authors: Ивашов А. , Ivashov A. , Мандра Ю. , Mandra J. , Зайцев Д. , Zaitsev D. , Панфилов П. , Panfilov P.
Published: August 2018

In a comparison of the deformation behavior under uniaxial compression of the composite material based on bis-GMA, UDMA, TEGDMA, PEGDMA and bis-EMA with the silicon and zirconium filler to create an adhesive connection and without adhesive compound. Describes the changes in the deformation behavior of each deformation curve. It is shown that the compound alters the adhesive strength characteristics of the sample due to the difference of Poisson’s ratio of the materials.
FEATURES DENTAL STATUS OF PATIENTS WITH TYPE II DIABETES IN THE HOSPITAL LEVEL
Authors: Еловикова Т. , Elovikova T. , Трошунин А. , Troshunin A. , Жукова Е. , Zhukova E. , Ожгихина Ж. , Ozhgikhina J.
Published: August 2018

Diabetes — a group of diseases characterized by hyperglycemia resulting from violations of insulin secretion, insulin action or both. The study revealed the following symptoms of the oral cavity in patients with type II diabetes mellitus: the mucous membrane swollen, pale, dry and shiny, tongue dry, wrinkled and pink, as well as poor hygiene, high intensity decay. Use mouthwash after first use showed significant improvements in the structure of the oral fluid.
THE ANTIMICROBIAL PROPERTIES OF THE DRUG BASED ON THE EXTRACT GRAPEFRUIT SEED (EXPERIMENTAL STUDY)
Authors: Протопопова Т. , Protopopova T. , Луницына Ю. , Lunitsyna J. , Порсева Ю. , Porseva J. , Токмакова С. , Tokmakova S. , Романцева Ю. , Romantsevа J.
Published: August 2018

The study of antimicrobial and antifungal activity of different concentrations of the drug on the representatives oral microflora.
CHAIRSIDE COLOR SCALES ; LIGHT - CURED COMPOSITES . ADVANTAGES AND DISADVANTAGES
Authors: Нуриева Н. , Nureyeva N. , Головин Н. , Golovin N.
Published: August 2018

Definition of a shade of a used sealing material is an important stage of restoration by means of light-cured composites. For this purpose use scales for definition of shades. Such scale is in each set of any light-cured composite. But clinical production of scales of shades and use them in clinical reception considerably increases quality of restoration.
COMPUTER TOMOGRAPHY AS A BASIC TOOL IN THE PLANNING AND FORECASTING OF COMPLEX DENTAL TREATMENT
Authors: Шлейко В. , Shleiko V. , Жолудев С. , Zholudev S.
Published: August 2018

On the examples of clinical cases the role of computer tomography in dental practice is shown.
DENTAL TREATMENT FOR CHILDREN UNDER GENERAL ANESTHESIA IN THE NPC «BONUM »
Authors: Скарюкина О. , Skaryukina O. , Елькин И. , Elkin I.
Published: August 2018

Opportunityto sanitize the mouth of the child with congenital and acquired disorders under general anesthesia in the hospital helps to maintain the quality of life and health of a young patient, facilitates and speeds up the healing process. The introduction of the pediatric practice of modern evaporative anesthetics can increase the volume of interventions to minimize operational risk and postoperative complications. Conducting simultaneous operations with surgeons otolaryngologists also significantly reduces the time and preoperative hospitalization of children.
EFFECTIVENESS ASSESSMENT TOOLS FOR THE REMINERALIZATION THERAPY
Authors: Сысоева О. , Sysoeva O. , Бондаренко О. , Bondarenko O. , Токмакова С. , Tokmakova S. , Дударева Е. , Dudareva E.
Published: August 2018

The article presents the comparative characteristic  of gels for remineralization therapy on the basis of calcium and phosphorus. Effect of the drugs studied by experimental and clinical evaluation of the effectiveness of remineralization therapy. Significant difference between the effectiveness of the studied funds were not found. Gels have a regulating influence on the process of remineralization in the oral cavity, increase the resistance of the surface layer of the tooth enamel to cariogenic factors and normalizes the saturation of the oral fluid microelements. 
LOSS OF AUTONOMIC PARASYMPATHETIC NODES OF THE HEAD IN THE STRUCTURE NEYROSTOMATOLOICHESKOGO RECEPTION
Authors: Журавлев В. , Zhuravlev V. , Николаева А. , Nikolaeva A.
Published: August 2018

The results of the analysis of the structure  neyrostomatologicheskogo reception. Features of clinical manifestations in patients with autonomic parasympathetic affected nodes. There was a high percentage of diagnostic errors by doctors, dentists and improper treatment of patients with this profile.
RATIONALE FOR USE IN THE TREATMENT CERAMIC INLAYS CARIES II CLASS IN BLACK POSTERIOR TEETH
Authors: Жолудев Д. , Zholudev D. , Медведев А. , Medvedev A. , Жолудев С. , Zholudev S.
Published: August 2018

Based on  the literature and our own clinical  observations in the article the use of ceramic inlays in class II cavities by Black in the posterior teeth.

 