bluuebunny/crossref_metadata_2025 huggingface dataset:
PRISÃO EM FLAGRANTE E A PRESUNÇÃO DE INOCÊNCIA: IMPLICAÇÕES NO PROCESSO PENAL
Authors: Ribeiro João Victor Nunes Lima Fonseca , Leonel Juliano de Oliveira
Published: October 2023

Todos os indivíduos têm direito à liberdade, conforme prevê a Constituição Federal de 1988, devendo a prisão ser apenas uma medida de exceção e ninguém pode ser considerado culpado antes da sentença condenatória com trânsito em julgado.. A presente pesquisa possui como tema a prisão em flagrante e a presunção de inocência e as suas implicações no processo penal brasileiro, com a investigação fundada em uma análise a partir dos Direitos Fundamentais. O objetivo geral da presente pesquisa buscará analisar à luz dos direitos fundamentais, se existe compatibilidade jurídica da prisão em flagrante delito em processo penal, frente ao princípio da presunção de inocência, previsto expressamente no art. 5º, LVII, da Constituição da República Federativa do Brasil de 1988. A metodologia da pesquisa está fundamentada em uma revisão bibliográfica ou literária, por meio da análise de várias teorias, presentes na jurisprudência e na doutrina, além de artigos científicos, disponibilizados em várias bases de dados, em especial a SCIELO e o Google Acadêmico. Concluiu-se por meio da presente pesquisa que somente há inconstitucionalidade da prisão em flagrante frente ao princípio constitucional da presunção da inocência caso não sejam respeitadas as formalidades referentes à medida da restrição de liberdade.
MANEJO DA SÍNDROME DE STEVENS-JOHNSON/NECRÓLISE EPIDÉRMICA TÓXICA, SECUNDÁRIA AO USO DE LAMOTRIGINA: UM RELATO DE CASO
Authors: Rodrigues Ananda Oliveira , Silva Caio Henrique Lopes e , Fonseca Gabriel Oliveira , Campana Juliana Caetano
Published: October 2023

A síndrome de Stevens-Johnson (SSJ) e a necrólise epidérmica tóxica (NET) são condições dermatológicas raras, porém com alta morbimortalidade. Os mecanismos patogênicos ainda não foram completamente esclarecidos, mas sabe-se que uma ampla variedade de medicamentos pode desencadear essas patologias, como anticonvulsivantes, antibióticos, analgésicos, antidepressivos, entre outros. A apresentação clínica da SSJ/NET é marcada pelo desenvolvimento de lesões cutâneas extensas que progridem com vesículas e bolhas, acometendo principalmente face e tórax, sendo antecedidas por sintomas gripais inespecíficos. As mucosas oral, ocular e genital são frequentemente afetadas, levando a complicações nutricionais e urinárias. Tendo em vista que ainda não existem protocolos para lidar com o paciente com SSJ e/ou NET, o presente trabalho objetiva relatar o manejo de um caso ocorrido no interior de Minas Gerais, desencadeado pelo uso de lamotrigina. Trata-se de uma paciente de 24 anos, do sexo feminino, que buscou o serviço de saúde por um quadro de sintomas gripais e sintomas iniciais de conjuntivite, seguidos de odinofagia, disúria e lesões vesicobolhosas dolorosas nas palmas das mãos e plantas dos pés. O diagnóstico dessas farmacodermias é baseado em uma anamnese minuciosa, buscando sinais e sintomas característicos e história recente de contato com algum agente causador. Novas pesquisas são necessárias nessa área, considerando que o tratamento ainda é controverso na literatura e faltam pesquisas que consolidem o manejo adequado dessa condição potencialmente fatal.
GLAUCOMA DE ÂNGULO ABERTO: AVALIAÇÃO CLÍNICA E OFTALMOLÓGICA
Authors: Terribele Natan , Vidal Jhennyfer Matos , Souza Diogo Quintino de , Costa Carolina Pâmela da , Rabello Isadora Pessoa Coimbra
Published: October 2023

O glaucoma de ângulo aberto é uma doença ocular crônica e progressiva, que se caracteriza pelo aumento da pressão intraocular e pela lesão do nervo óptico, podendo levar à perda irreversível da visão. Essa doença é a principal causa de cegueira irreversível no mundo, afetando cerca de 70 milhões de pessoas. O glaucoma de ângulo aberto é uma doença silenciosa, que não apresenta sintomas na fase inicial, dificultando o seu diagnóstico precoce e o seu tratamento adequado. Objetivo: analisar os métodos e os critérios utilizados para a avaliação clínica e oftalmológica dos pacientes com glaucoma de ângulo aberto, bem como os resultados obtidos com essas avaliações. Metodologia: Para realizar esta revisão, foi utilizada a metodologia baseada no checklist PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), que consiste em uma série de critérios para garantir a qualidade e a transparência dos estudos revisados. Foram consultadas as bases de dados PubMed, Scielo, Web of Science, utilizando os seguintes descritores: "open-angle glaucoma", "clinical evaluation", "ophthalmic evaluation", "diagnosis" and "treatment". Foram incluídos apenas artigos publicados nos últimos 10 anos, que abordassem pacientes com glaucoma de ângulo aberto, que realizassem alguma forma de avaliação clínica ou oftalmológica. Foram excluídos artigos que não apresentassem dados clínicos ou oftalmológicos dos pacientes, que fossem revisões ou relatos de caso, ou que não estivessem disponíveis na íntegra. Resultados: Após a aplicação dos critérios de inclusão e exclusão, foram selecionados 15 artigos para a análise. A avaliação clínica dos pacientes com glaucoma de ângulo aberto envolve a anamnese, o exame físico geral e o exame neurológico. Essa avaliação tem como objetivo identificar os fatores de risco, os sinais e os sintomas da doença, bem como as possíveis comorbidades ou complicações associadas. A avaliação oftalmológica dos pacientes com glaucoma de ângulo aberto envolve a acuidade visual, a tonometria, a gonioscopia, a biomicroscopia, a fundoscopia, a paquimetria, a campimetria e a tomografia de coerência óptica. Essa avaliação tem como objetivo medir a pressão intraocular, avaliar o ângulo da câmara anterior, examinar as estruturas oculares, detectar as alterações do nervo óptico e da retina, determinar a espessura da córnea, verificar o campo visual e quantificar a espessura das fibras nervosas retinianas. Conclusão: A avaliação clínica e oftalmológica dos pacientes com glaucoma de ângulo aberto é um processo complexo e multidimensional, que requer o uso de diversos métodos e critérios. Essa avaliação é essencial para o manejo adequado da doença, que é uma das principais causas de cegueira irreversível no mundo.
Cybersécurité des systèmes industriels cyber-physiques
Authors: GALLAIS Antoine , IMINE Youcef
Published: October 2023

La transition numérique dans l’industrie se traduit par de nouveaux services s’appuyant sur les données issues de divers objets (capteurs, actuateurs, robots) au sein des ICPS. L’évolution rapide du nombre d’objets et des tâches qui y sont effectuées a augmenté la surface d’attaque des réseaux industriels. Le risque d’incident cyber augmente alors considérablement. La cybersécurité des systèmes cyber-physiques industriels est aujourd’hui au cœur des préoccupations, amplifiées par les récentes attaques sophistiquées, les exploits et les failles dans la conception de logiciels et de matériels.
Compilation of Henry's law constants (version 5.0.0) for water as solvent
Authors: Sander Rolf
Published: October 2023

Abstract. Many atmospheric chemicals occur in the gas phase as well as in liquid cloud droplets and aerosol particles. Therefore, it is necessary to understand their distribution between the phases. According to Henry’s law, the equilibrium ratio between the abundances in the gas phase and in the aqueous phase is constant for a dilute solution. Henry’s law constants of trace gases of potential importance in environmental chemistry have been collected and converted into a uniform format. The compilation contains 46 434 values of Henry’s law constants for 10 173 species, collected from 995 references. It is also available on the internet at https://www.henrys-law.org (last access: October 2023). This article is a living review that supersedes the now obsolete publication by Sander (2015).
An integrated and homogenized global surface solar radiation dataset and its reconstruction based on a convolutional neural network approach
Authors: Jiao Boyang , Su Yucheng , Li Qingxiang , Manara Veronica , Wild Martin
Published: October 2023

Abstract. Surface solar radiation (SSR) is an essential factor in the flow of surface
energy, enabling accurate capturing of long-term climate change and
understanding of the energy balance of Earth's atmosphere system. However, the
long-term trend estimation of SSR is subject to significant uncertainties
due to the temporal inhomogeneity and the uneven spatial distribution of in situ observations. This paper develops an observational integrated and
homogenized global terrestrial (except for Antarctica) station SSR dataset (SSRIHstation) by integrating all available SSR observations,
including the existing homogenized SSR results. The series is then
interpolated in order to obtain a 5∘ × 5∘
resolution gridded dataset (SSRIHgrid). On this basis, we further
reconstruct a long-term (1955–2018) global land (except for Antarctica) SSR
anomaly dataset with a 5∘ × 2.5∘ resolution
(SSRIH20CR) by training improved partial convolutional neural network
deep-learning methods based on 20th Century Reanalysis version 3 (20CRv3). Based on this, we
analysed the global land- (except for Antarctica) and regional-scale SSR trends
and spatiotemporal variations. The reconstruction results reflect the
distribution of SSR anomalies and have high reliability in filling and
reconstructing the missing values. At the global land (except for
Antarctica) scale, the decreasing trend of the SSRIH20CR (−1.276 ± 0.205 W m−2 per decade) is smaller than the trend of the SSRIHgrid (−1.776 ± 0.230 W m−2 per decade) from 1955 to
1991. The trend of the SSRIH20CR (0.697 ± 0.359 W m−2 per decade)
from 1991 to 2018 is also marginally lower than that of the SSRIHgrid
(0.851 ± 0.410 W m−2 per decade). At the regional scale, the
difference between the SSRIH20CR and SSRIHgrid is more significant
in years and areas with insufficient coverage. Asia, Africa, Europe and
North America cause the global dimming of the SSRIH20CR, while Europe
and North America drive the global brightening of the SSRIH20CR.
Spatial sampling inadequacies have largely contributed to a bias in the
long-term variation of global and regional SSR. This paper's homogenized
gridded dataset and the Artificial Intelligence reconstruction gridded
dataset (Jiao and Li, 2023) are both available at https://doi.org/10.6084/m9.figshare.21625079.v1.
Emulating lateral gravity wave propagation in a global chemistry–climate model (EMAC v2.55.2) through horizontal flux redistribution
Authors: Eichinger Roland , Rhode Sebastian , Garny Hella , Preusse Peter , Pisoft Petr , Kuchař Aleš , Jöckel Patrick , Kerkweg Astrid , Kern Bastian
Published: October 2023

Abstract. The columnar approach of gravity wave (GW) parameterisations in weather and climate models
has been identified as a potential reason for dynamical biases in middle-atmospheric dynamics.
For example, GW momentum flux (GWMF) discrepancies between models and observations at 60∘ S arising
through the lack of horizontal orographic GW propagation are suspected to cause deficiencies
in representing the Antarctic polar vortex.
However, due to the decomposition of the model domains onto different computing tasks for
parallelisation, communication between horizontal grid boxes is computationally extremely
expensive, making horizontal propagation of GWs unfeasible for global chemistry–climate simulations. To overcome this issue, we present a simplified solution to approximate horizontal
GW propagation through redistribution of the GWMF at one single
altitude by means of tailor-made redistribution maps.
To generate the global redistribution maps averaged for each grid box, we use a
parameterisation describing orography as a set of mountain ridges with
specified location, orientation and height combined with a
ray-tracing model describing lateral propagation of so-generated mountain waves.
In the global chemistry–climate model (CCM) EMAC (ECHAM MESSy Atmospheric Chemistry),
these maps then allow us to redistribute the GW momentum
flux horizontally at one level, obtaining an affordable overhead of computing resources.
The results of our simulations show GWMF and drag patterns that are horizontally
more spread out than with the purely columnar approach;
GWs are now also present above the ocean and regions without mountains.
In this paper, we provide a detailed description of how the redistribution maps
are computed and how the GWMF redistribution is implemented in the CCM.
Moreover, an analysis shows why 15 km is the ideal altitude for the redistribution.
First results with the redistributed orographic GWMF provide clear evidence that
the redistributed GW drag in the Southern Hemisphere has the potential to modify and improve
Antarctic polar vortex dynamics, thereby paving
the way for enhanced credibility of CCM simulations and projections of polar stratospheric ozone.
Calibrating macroscale hydrological models in poorly gauged and heavily regulated basins
Authors: Vu Dung Trung , Dang Thanh Duc , Pianosi Francesca , Galelli Stefano
Published: October 2023

Abstract. The calibration of macroscale hydrological models is often challenged by the lack of adequate observations of river discharge and infrastructure operations. This modeling backdrop creates a number of potential pitfalls for model calibration, potentially affecting the reliability of hydrological models. Here, we introduce a novel numerical framework conceived to explore and overcome these pitfalls. Our framework consists of VIC-Res (a macroscale model setup for the Upper Mekong Basin), which is a novel variant of the Variable Infiltration Capacity (VIC) model that includes a module for representing reservoir operations, and a hydraulic model used to infer discharge time series from satellite data. Using these two models and global sensitivity analysis, we show the existence of a strong relationship between the parameterization of the hydraulic model and the performance of VIC-Res – a codependence that emerges for a variety of performance metrics that we considered. Using the results provided by the sensitivity analysis, we propose an approach for breaking this codependence and informing the hydrological model calibration, which we finally carry out with the aid of a multi-objective optimization algorithm. The approach used in this study could integrate multiple remotely sensed observations and is transferable to other poorly gauged and heavily regulated river basins.
Sensitivity of the MAR regional climate model snowpack to the parameterization of the assimilation of satellite-derived wet-snow masks on the Antarctic Peninsula
Authors: Dethinne Thomas , Glaude Quentin , Picard Ghislain , Kittel Christoph , Alexander Patrick , Orban Anne , Fettweis Xavier
Published: October 2023

Abstract. Both regional climate models (RCMs) and remote sensing (RS) data are essential tools in understanding the response of polar regions to climate change. RCMs can simulate how certain climate variables, such as surface melt, runoff and snowfall, are likely to change in response to different climate scenarios but are subject to biases and errors. RS data can assist in reducing and quantifying model uncertainties by providing indirect observations of the modeled variables on the present climate. In this work, we improve on an existing scheme to assimilate RS wet snow occurrence data with the “Modèle Atmosphérique Régional” (MAR) RCM and investigate the sensitivity of the RCM to the parameters of the scheme. The assimilation is performed by nudging the MAR snowpack temperature to match the presence of liquid water observed by satellites. The sensitivity of the assimilation method is tested by modifying parameters such as the depth to which the MAR snowpack is warmed or cooled, the quantity of water required to qualify a MAR pixel as “wet” (0.1 % or 0.2 % of the snowpack mass being water), and assimilating different RS datasets. Data assimilation is carried out on the Antarctic Peninsula for the 2019–2021 period. The results show an increase in meltwater production (+66.7 % on average, or +95 Gt), along with a small decrease in surface mass balance (SMB) (−4.5 % on average, or −20 Gt) for the 2019–2020 melt season after assimilation. The model is sensitive to the tested parameters, albeit with varying orders of magnitude. The prescribed warming depth has a larger impact on the resulting surface melt production than the liquid water content (LWC) threshold due to strong refreezing occurring within the top layers of the snowpack. The values tested for the LWC threshold are lower than the LWC for typical melt days (approximately 1.2 %) and impact results mainly at the beginning and end of the melting period. The assimilation method will allow for the estimation of uncertainty in MAR meltwater production and will enable the identification of potential issues in modeling near-surface snowpack processes, paving the way for more accurate simulations of snow processes in model projections.
INTERSUBJECT AGREEMENTS AS SOURCES OF LEGAL REGULATION OF SPATIAL DEVELOPMENT IN THE RUSSIAN FEDERATION
Authors: БУЛАТОВА З.А.
Published: October 2023

В статье рассматриваются вопросы, связанные с межсубъектными договорами как источни- ками правового регулирования пространственного развития в Российской Федерации. Анализируются колли- зионные вопросы правового регулирования взаимодействия субъектов Российской Федерации по различным областям общественных отношений.

The article deals with issues related to intersubject agreements as sources of legal regulation of spatial development in the Russian Federation. The conflict of laws issues of legal regulation of interaction of the subjects of the Russian Federation in various areas of public relations are analyzed.
THE ROLE OF THE BANK OF RUSSIA IN LEGAL REGULATION ISSUANCE AND CIRCULATION OF DIGITAL FINANCIAL ASSETS
Authors: ЦУПИКОВ А.Н.
Published: October 2023

В начале 2022 года Банк России включил несколько организаций в реестр операторов ин- формационных систем, осуществляющих выпуск цифровых финансовых активов. Этот можно считать отправ- ной точкой в практическом применении норм законодательства, регулирующих сферу выпуска и обращения цифровых финансовых активов. Предметом настоящей статьи является исследование роли Банка России в правовом регулировании выпуска и обращения цифровых финансовых активов; анализ законодательства, ре- гулирующего участие Банка России в процессе контроля, регулирования выпуска и обращения цифровых фи- нансовых активов, с целью понимания его роли как мегарегулятора и дальнейших тенденций усиления влияния Банка России на рынок цифровых финансовых активов. Результатом исследования стало понимание достаточности законодательного регулирования участия Бан- ка России в контроле над выпуском и обращением цифровых финансовых активов и недостаточности научного обоснования отнесения сферы цифровых финансовых активов к понятию «финансовые рынки».

At the beginning of 2022, the Bank of Russia included several organizations in the register of information system operators issuing digital financial assets. This can be considered a starting point in the practical application of the norms of legislation regulating the sphere of issuance and circulation of digital financial assets. The subject of this article is the study of the role of the Bank of Russia in the legal regulation of the issuance and circulation of digital financial assets. Analysis of the legislation regulating the participation of the Bank of Russia in the process of controlling, regulating the issuance and circulation of digital financial assets in order to understand its role as a mega-regulator and further trends in strengthening the influence of the Bank of Russia on the digital financial assets market. The result of the study was an understanding of the sufficiency of legislative regulation of the participation of the Bank of Russia in controlling the issuance and circulation of digital financial assets and the insufficiency of scientific justification for attributing the sphere of digital financial assets to the concept of financial markets.
COUNTERING ABUSES IN INTENTIONAL BANKRUPTCY PROCEDURES AIMED AT TAX EVASION
Authors: ОРДИНАРЦЕВ И.И.
Published: October 2023

В данной работе автор описывает основные способы противодействия злоупотреблениям в процедурах преднамеренного банкротства, реализуемого посредством уголовно-правового инструментария. На основании эмпирического материала подчеркивается значимость деятельности государственных органов и организаций в банкротной практике. Автором отстаивается идея активного использования уголовно-правовых механизмов защиты экономических интересов физических и юридических лиц.

In this paper, the author describes the main ways to counter abuse in the procedures of intentional bankruptcy, implemented through criminal legal tools. Based on empirical material, the importance of the activities of state bodies and organizations in bankruptcy practice is emphasized. The author defends the idea of the active use of criminal law mechanisms to protect the economic interests of individuals and legal entities.
PECULIARITIES OF INTERROGATION OF A SUSPECT IN CASES OF ALCOHOLIC PRODUCTS AND (OR) TOBACCO PRODUCTS CONTRABAND
Authors: ИСАЕВ А.И.
Published: October 2023

Данная статья направлена на анализ типичных следов контрабанды алкогольной продукции и (или) табачных изделий, которые формируют следовую картину преступления. Данный вид контрабанды, ответ- ственность за которую предусмотрена статьей 200.2 УК РФ, является серьезным таможенным преступлением, расследование которого осложнено множеством факторов, в том числе потребностью преступника подготав- ливаться к его совершению, что минимизирует объем информации, оставленной преступником, которая может быть использована лицом, расследующим преступление. Для его раскрытия требуется учет всех возможных источников криминалистически значимой информации, выражающейся как в материальных, так и идеальных следах совершенного преступления. В данной статье на основании анализа следственно-судебной практики выявлены ключевые виды материальных и идеальных следов, дана их краткая характеристика. Выявлено, ка- кие категории следов (следы-предметы, следы-вещества, следы-отображения) встречаются на практике наи- более часто. Особое внимание уделено таким аспектам, как предмет контрабанды, свидетельские показания.

This article is aimed at analyzing typical traces of smuggling of alcoholic products and (or) tobacco products, which form a trace picture of a crime. This type of smuggling, the responsibility for which is provided for in Article 200.2 of the Criminal Code of the Russian Federation, is a serious customs crime, the investigation of which is complicated by many factors, including the need for the criminal to prepare for its commission, which minimizes the amount of information left by the criminal, which can be used by a person investigating a crime. To disclose it, it is necessary to take into account all possible sources of forensically significant information, expressed both in material and ideal traces of the crime committed. In this article, based on the analysis of investigative and judicial practice, key types of material and ideal traces are identified, and their brief description is given. It was revealed which categories of traces (traces-objects, traces-substances, traces-displays) are most often encountered in practice. Particular attention is paid to such aspects as the subject of smuggling, testimonies.
Un poco de política. Jean-Luc Godard, la ciudad y la subjetividad contemporánea. Valle Corpas, Irene (2023). Granada: Editorial Universidad de Granada, págs., 368.
Authors: Sousa-Pardo Carmen
Published: October 2023

Reseña de Valle Corpas, Irene (2023). Un poco de política. Jean-Luc Godard, la ciudad y la subjetividad contemporánea. Granada: Editorial Universidad de Granada, págs., 368
Trazar circunferencias expansivas
Authors: Parra-Bañón José J.
Published: October 2023

Vicente Luis Mora (2022). Circular 22. Barcelona: Galaxia Gutenberg. 636 pp. ISBN: 978-84-19075-46-8
A Study to Assess the Knowledge, Perceived Challenges, and Coping Strategies on Home Care Management Among Caregivers of Mentally Ill Patients with the View to Evaluate the Effectiveness of an Information Booklet on the Knowledge of Home Care Management in a Selected Hospital of Delhi
Authors: . Deepa , Kapoor Bimla , Biswas Mitali
Published: October 2023

The objectives of the study were: To assess the knowledge, perceived challenges, and coping strategies of caregivers on home care management of mentally ill patients, to seek association between knowledge and demographic variables and previous knowledge of home care, to develop and evaluate the effectiveness of an information booklet on the knowledge on home care management. to determine the correlation between knowledge and perceived challenges.
Materials And Methods: This study was carried out in two phases in which the assessment of knowledge on home care, perceived challenges and coping strategies was done in phase-I and evaluation of the effectiveness of information booklet on home care management was done in phase-II. The sample were 100 caregivers of mentally ill patients in phase-I and 37 caregivers in phase-II. The sampling technique was purposive for both the phases. The tool used were structured knowledge questionnaire, rating scale and standardized brief COPE for coping strategies.
Results: Major findings of the study revealed 63% of caregivers of mentally ill patients had good level of knowledge. It was found that majority of the caregivers e.g., 68% of mentally ill patients were having moderately perceived challenges. Most of the caregivers of mentally ill patients used problem focused coping style. There was a positive correlation between knowledge and perceived challenges. Based on the findings in Phase-I the information booklet on home care management was developed. The development of informational booklet on home care management was effective to increase the knowledge of the caregivers.

Key words: [Home Care Management, Perceived Challenges, Caregivers of mentally ill patients]
The Plan of Breast Feeding Friendly Work Place
Authors: Choukikar Yogesh , Kumar K. Shrinidhi , Kumar Raj
Published: October 2023

Government gives 6 months of maternity leave Breast milk is right of the baby. Even U.S didn’t have this. India is better than other country for as breast feeding awareness is considered. But many private sectors will not follow this rule. We can reduce leave in the antenatal period and same will be added to post-natal life. The uneducated will feed the bay problem with educated or half educated Breast feeding is great investment because that child will be good in study, he we not fall sick he has got good emotional relationship with family members what else you need? Mother with breast fed to baby will have great self-esteem. After 6 months she has to resume to works she may stop, although dependency of the baby is less but need to continuity. After 6 month you can continue with expressed breast milk working place have a private room to express the milk and provide to the baby. Even in the home also she can express the breast milk and keep it in the refrigerators by storing it in a vessel which is also sterilized and label it.

Key words: Breast feeding, EBM, working place, EBF
Spontaneous Tooth Exfoliation Secondary to Osteoradionecrosis of Jaw Bones - A Case Report
Authors: Rana Priyanka , Sekhar Reddy M Chandra , Sravanthi Y Mercy
Published: October 2023

Osteoradionecrosis of the jaws is a serious and grave sequalae of therapeutic radiotherapy given for head and neck malignancies. It is a delayed process where irradiated bone becomes necrosed leading to its exposure. The most common signs and symptoms are localized pain, dysesthesia, bone exposure, sino-cutaneous or oro-cutaneous fistula, trismus, and pathological fractures.
This article describes a documented instance of osteoradionecrosis affecting the jaws. The patient in this case experienced exposed and necrotic bone in both the anterior maxilla and mandible within six months after undergoing radiotherapy for grade III choroid plexus carcinoma.

Key words: Radiotherapy, Osteoradionecrosis of jaw, Necrosis
A Study to Find Out the Effect of Chair Aerobics Exercise on Fasting Blood Glucose in Type-2 Diabetes Mellitus Patients - An Interventional Study
Authors: Makrani Haseena , Gondaliya Pragna , Mehta Devki
Published: October 2023

Background and need of research: Walking is a component of diabetes mellitus (DM) care guidelines due to its favourable effects on Glycaemic control but many elderly Diabetics are unable to walk due to many reasons. Chair aerobics is a form of aerobic exercise Performed while sitting in a chair which includes rhythmic upper and lower body movements.
Methods: 30 patients were included. Chair aerobics as a low-intensity exercise training was given. Pre- and post-exercise outcome measurements in the form of FBS were recorded.
Result: The study showed a statistically significant difference in FBS (< 0.05.)
Conclusion and clinical implications: Chair aerobics as low-intensity exercise training demonstrated improvement in fasting blood glucose in type- 2 diabetes mellitus patients.

Key words: Chair aerobics, diabetes mellitus, elderly
Postnatal Care Visit and Its Determinants Among Mothers in Chitwan, Nepal: A Mixed-Method Study
Authors: Adhikari Indira , Kiran Poudel Prakriti
Published: October 2023

BACKGROUND: Postnatal care for six weeks after giving birth is vital for the health of both mother and newborn. The postnatal period is dangerous for both mother and baby, where morbidity and mortality are highly prevalent if proper care is not done. PNC visits should be more noticed, creating a missing link towards safe motherhood. This research examines the social and cultural influences that affect postnatal care practices among mothers with infants under one.
METHOD: This study utilized a combination of methods, primarily emphasizing quantitative techniques. It was conducted in Madi, Rapti, and Ratnanagar municipalities in Chitwan, utilizing a cluster random sampling technique. Data was gathered through 527 face-to-face interviews utilizing a structured questionnaire for quantitative data, six focus group discussions and three key informant interviews for qualitative data. The quantitative and qualitative data were analyzed using logistic regression and by the thematic content analysis method, respectively. The statistical analysis was conducted using SPSS version 21.
RESULT: Based on the study's findings, it was revealed that most participants surveyed were between the ages of 20 and 24 and engaged in household and agricultural work. Of the 527 respondents, 79.1% were aware of partial postnatal visits, only 20.9% knew about complete postnatal visits, and 11.8% reported practicing PNC visits. Our analysis, which employed binary logistic regression, uncovered that social and cultural factors significantly impacted postnatal care visits and practices. The most influential factors for PNC visits and practices were occupation, antenatal care visits, mode of delivery, time to reach healthcare facilities and healthcare-seeking behavior. Qualitative data was also collected through FGD and IDIs to support our quantitative data, and both analyses indicated that social and cultural factors influence postnatal care visits among mothers.
CONCLUSION: Fewer mothers reported about aware and complete Postnatal care visit. The major confounding factors for PNC visits and practices were occupation, antenatal care visits, mode of delivery, time to reach health facilities, and healthcare-seeking behaviour. It is essential to involve both traditional and religious leaders to address these issues effectively. Local health organizations should conduct postnatal care visits by going door-to-door to identify and manage problems.

Key words: Postnatal Care, Visit, Mother, Social, Cultural, Factors, Nepal
Molecular Characterization of HIV-1 among Female Sex Workers (FSWs) in Five Departments of the Republic of Congo
Authors: Lesly Mboussa Barronne , Loukabou Mbongolo Nadia Claricelle , Arnold Malonga Gervillien
Published: October 2023

Introduction: HIV-1, an infectious agent with the greatest sequence diversity, including higher recombination rates. The objective of this study is to assess the genetic diversity of HIV-1 in FSWs in Congo.
Methods: A total of 39 plasma samples from FSWs ART-naive HIV-1-seropositive were collected from urban and semi-urban areas of the Republic of Congo. HIV-1 viral loads were determined by RT-PCR according the manufacturer’s instructions of the Abbott® m2000 Real-Time System. Complementary DNA synthesis and PCR amplification of HIV reverse transcriptase gene was performed from extracts of samples with a viral load > 1000 copies/mL by Nested PCR and products was sequencing by using an ABI 3500XL Genetic Analyzer for determined genetic diversity of HIV strains and the antiretroviral resistance profile.
Results: Of the 39 samples extracted, only 14 had a viral load greater than or equal to 1000 copies/ml. We were able to sequence 12 samples. It emerges that five subtypes of HIV-1 (A, G, J, H, D) and a recombinant form, CRF02_AG circulate among FSWs. Subtype A was more predominant with 41% followed by subtype G (25%). Subtypes D, H, J and CRF02_AG had a proportion of 8.33% each. Two samples showed major G190GA mutations conferring resistance to INNRT like NVP, V106VA and M184MV to INRTs such as DOR, NVP FTC and 3TC. Minor mutations such as: K70N, T215TN, E138A and V179E causing intermediate resistances to: EFV, ABC, D4T, DDI, TDF.
Conclusions: This study showed a predominance of subtype A followed by G then J, H, D subtypes and recombinant form CR02_AG in FSWs. Despite the small study sample size, continued analysis of HIV-1 viral loads and sequences in this population of FSWs is of considerable interest to examine and monitor genetic variability.

Key words: HIV-1 molecular characterization, HIV-1 drug resistance mutations, Female Sex Workers, Republic of Congo
Photocatalytic degradation of Orange-II by surfactant assisted Mn/Mg co-doped TiO2 nanoparticles under visible light irradiation
Authors: Miditana Sankara Rao , Tirukkovalluri Siva Rao , Raju Imandi Manga , Alim Shaik Abdul
Published: October 2023

In this research, the photocatalytic effect was studied for sol-gel synthesized Mn/Mg co-doped metal oxide (TiO2) nanoparticles (NPs), which are encapsulated with anionic Gemini surfactant. The physicochemical properties of Mn/Mg co-doped TiO2 were investigated using a variety of characterization techniques, FT-IR, UV Vis-DRS, XRD, SEM, EDX, TEM, BET and PL. Characterization results reveal that Mn/Mg dopants stabilize TiO2 in the form of anatase phase and reduce the bandgap energy. Presence of strong chemical bonding and functional groups at the interface of dopant and TiO2 NPs was confirmed with FT-IR. The photocatalytic activity of these catalysts was assessed by the degradation of Orange II (AO7) using visible light irradiation. Of the variable nanomaterials MMT5-GS2 showed remarkable results. The photoluminescence studies revealed that OH radicals are the reactive species and responsible for oxidative photocatalytic degradation of Orange II.
Development of 2-dimensional and 3-dimensional QSAR models of Indazole derivatives as TTK inhibitors having Anticancer potential
Authors: Yadav Mithlesh , Narasimhan Balasubramanian , Kapoor Archana
Published: October 2023

The study aimed to explore the anticancer efficacy of indazole pharmacophore by analyzing a series of 109 derivatives of indazole as Tyrosine Threonine Kinase (TTK) inhibitors through quantitative activity relationship analysis using 2D and 3D QSAR techniques. The best 2D-QSAR model was generated by the MLR method, showing a high correlation coefficient (r2) of 0.9512, and good internal (q2), and external (pred_r2) cross-validation regression coefficients of 0.8998, and 0.8661, respectively. The residual values were modest, indicating good agreement between the observed and predicted pIC50 values, which suggested that the chosen model was predictably accurate. The 3D QSAR model, built using the SWF kNN approach, displayed a high internal cross-validation regression coefficient (q2) of 0.9132. Essential structural features/considerations in developing indazole as prospective anticancer medicines have been suggested. The study provides a reliable and predictive model for the prediction of anticancer activity of indazole derivatives. The identified essential structural features/considerations may be useful for the development of prospective anticancer medicines.
In silico investigations on the repurposing of antivirals for Covid-19 and pharmacophore modelling
Authors: Raphael Vinod P , Shaju K.S. , Bindu T.K. , Sini A.
Published: October 2023

The pandemic COVID-19 has been spreading around the globe from December 2019 onwards and is considered the most infectious disease of this century. To date, there is no effective drug against SARS-CoV-2 discovered by pharmaceutical scientists, and the research is going rigorously all over the world. In this work, we examined the interaction of the already existing antivirals (Lopinavir, Atazanavir, and Remdesivir) with the structural proteins of SARS-CoV-2 using computational methods. Pharmacophore modeling of these drugs was conducted using molecular databases to determine the lead compounds from molecular databases. Pharmagist Webserver and Zinc Molecular Database were used to find out the pharmacophore and lead compounds, respectively. The drug-likeness properties of the compounds were evaluated by the SwissADME webserver. In silico studies showed that the binding affinities of the drugs followed the order Remdesivir > Atazanavir > Lopinavir. Docking and pharmacological studies revealed the potency and drug-likeness of the synthetic molecules.
Sosyal Bilgiler 4. ve 5. Sınıf Ders Kitaplarında Biyografi Kullanımının İncelenmesi
Authors: GÖZETEN Serdar , ŞİMŞEK Zeynep , İRİŞİK Sezgin , YAMAN Gülden , UZ Mehmet , GÜNDOĞAN Haluk Kemal , ÖZKAN Hakan
Published: October 2023

Sosyal Bilgiler öğretiminde ders kitapları, eğitim öğretim süreçlerinde kullanılan temel kaynakların başında yer almaktadır. On iki yıllık zorunlu eğitim sürecinde Sosyal Bilgiler dersi, ilkokul dördüncü sınıftan itibaren bireylerin bağlı olduğu toplumdaki sosyal yaşamla ilgili görüş ve düşüncelerini biçimlendirmeleri ve bireylerin doğaya, topluma ve içinde yaşadığı dünyaya karşı olumlu ve yapıcı tutumlar geliştirmeleri açısından oldukça önemlidir. Son yıllarda Sosyal Bilgiler dersinin öğretiminde öğrenciyi merkeze alan yöntem ve tekniklerin sınıflarda uygulanması konusundaki bilgi ve uygulama yetersizliği dikkatleri çekmektedir. Çalışmanın temel amacı 2022/2023 eğitim öğretim yılında 4. ve 5. sınıf Sosyal Bilgiler ders kitaplarında biyografi kullanım durumunun incelenmesidir. Bu nedenle, Sosyal Bilgiler dersinin eğitim ve öğretiminde yeni yöntem ve teknikler konusunda yapılan literatürdeki araştırmalar ile daha etkili Sosyal Bilgiler öğretimi için kavramlardan, görsel materyallerden ve edebiyattan nasıl yararlanılabileceği üzerinde durulmaktadır. Araştırmada nitel araştırma yöntemlerinden doküman inceleme yöntemi kullanılmıştır. Araştırmada doküman olarak Milli Eğitim Bakanlığı (MEB) tarafından hazırlanan İlköğretim Sosyal Bilgiler 4. ve 5. sınıf ders kitaplarından yararlanılmıştır. Araştırmanın sonucunda elde edilen veriler içerik analizine tabi tutularak çözümlenmiştir. Yapılan araştırmanın sonuçlarına göre 4. sınıf ders kitabında 19 biyografi 5. sınıf ders kitabında ise 10 biyografi olmak üzere toplam 29 kişinin biyografisine yer verildiği görülmüştür. Bazı ünitelerde çok bazı ünitelerde az biyografi kullanılmıştır. Buna karşılık bazı ünitelerde ise hiç biyografi kullanılmadığı tespit edilmiştir. Araştırmada biyografisi kullanılan 29 kişiden 27’sinin erkek 2’sinin ise kadın olduğu tespit edilmiştir. Araştırmanın sonuçlarına göre Sosyal Bilgiler ders kitabındaki bütün ünitelerde uygun kişiler araştırılarak biyografi kullanımında eşit dağılım yapılması ve kadın biyografilerine de daha fazla yer verilmesi önerileri sunulmuştur.
Effectiveness of Planned Teaching about knowledge regarding ill health effects of Chemical ripening of fruits and vegetables among farmers in selected rural area
Authors: Swapnil Lakade Snehal , Gawali Vinay
Published: October 2023

The study titled “Effectiveness of planned teaching about knowledge regarding ill health effects of chemical ripening of fruits and vegetables among farmers in selected rural area” was conducted with the objectives to assess the existing knowledge regarding ill health effects of chemical ripening of fruits and vegetables among farmers, to evaluate the effectiveness of planned teaching programme regarding ill health effects of chemical ripening of fruits and vegetables among farmers. A pre experimental and descriptive evaluatory research approach was used with one group pre-test post-test design to evaluate the effectiveness of planned teaching. The tool used for data collection was a structured questionnaire which comprised 4 items in demographic data and 30 items on ill health effects of chemical ripening of fruits and vegetables. The reliability of tool was established by Spilt Half method. The pre-test was administered to 60 farmers followed by the planned teaching, After 7 (seven) days, post-test was conducted to the subject using the same tool. Regarding the existing knowledge of the farmers, there was a lack of knowledge in all aspects of ill health effects of chemical ripening of fruits and vegetables. The overall mean percentage of post-test knowledge scores of the farmers 65.66% was apparently higher than the overall mean percentage of pre-test knowledge score 35.55% and was significant at 0.1% level. Paired t‟= 35.91, p<0.05. In pretest, 8.33% of them had poor and 91.67% had average level of knowledge score. The major findings revealed that planned teaching enhanced the knowledge of the farmers about ill health effects of chemical ripening of fruits and vegetables.
Pre-Experimental Study to Assess the Effectiveness of Structured Teaching Programme on Knowledge regarding Kangaroo Mother Care among III-year BSc Nursing Students
Authors: V. Nair Vijayasree.
Published: October 2023

Background: A pre-experimental study was conducted to assess the effectiveness of structured teaching programme on knowledge regarding Kangaroo mother care among III-year B.Sc. Nursing students in selected Nursing College, Tumkur district, Karnataka. A total sample of 60, III-year B.Sc. (N) students were selected using Simple random sampling technique. The objectives of the study were to assess the knowledge level among III-year BSc. nursing students regarding kangaroo mother care before and after structured teaching programme and to find out the effectiveness of structured teaching programme on knowledge regarding kangaroo mother care among nursing students. The final objective was to determine the association between pre-test level of knowledge and selected demographic variables. Materials and Methods: A one-group pre-test post-test design was used to conduct the study. A sample comprising of 60 students were enrolled using simple random sampling technique. The conceptual framework of the study was based on Ludwig VonBertalanffy’s General System Model. Tools used for data collection were demographic Performa and structured knowledge questionnaire.
Results: Data analysis was done using descriptive and inferential statistics. Findings of the study revealed that the mean post-test knowledge score 25.12±2.41was significantly higher than the mean pre-test knowledge score 14.36±3.47 (p<0.01). Paired t value computed at 21.56** was statistically significant at p<0.01. which revealed that, there is significant increase in the mean post-test knowledge score. Significant association at 0.05 level was observed between knowledge with regard to their previous knowledge. Conclusion: The findings of the study confirmed that the structured teaching programme was significantly effective in improving the knowledge on kangaroo mother care amongIII year B.Sc. nursing students.
A Study to assess the Maternal Health among the Primipara Mothers in selected Hospital at Mysuru
Authors: Jha Chanda , J Lissa
Published: October 2023

BACKGROUND AND OBJECTIVES: The aim of study was to assess the maternal health among primipara mothers in selected hospital at Mysuru. OBJECTIVES: 1. To assess the maternal health. 2. To find the association between maternal health with obstetrical history of mothers. METHODS: In this study, descriptive design was used and non-probability convenient sampling technique was adopted to select primipara mothers from selected Hospital at Mysuru. Pilot study was conducted, the tool and study design were found to be feasible. Maternal health of primipara mothers were assessed by using checklist and interview method. was validated by experts and reliability was established by rater inter rated method. The data were collected and analysed using descriptive and inferential statistics. RESULT: The study results revealed that, majority 56% of the mothers age ranges between 24-29 years; majority 90% of the mother has initiated their antenatal visit before 12 weeks of gestation; all the mothers had taken both dose of TD vaccine, iron, folic acid and calcium tablet intake during pregnancy; Most of the mothers i.e. 52% have gained their weight in between 10-14 kg of her weight during her pregnancy; majority 55% of the mothers had undergone for cesarean section; most of the baby’s health condition was healthy. There was no statistically significant association found between maternal health of mothers with initiation of antenatal care, total weight gain of mother in kg, height of the mother in cm, conception of pregnancy and week of gestation at birth except with type of delivery ꭓ2 14.91 and condition of baby at birth ꭓ2 4.84 found to be significant at 0.05 level of significance. CONCLUSION: The study concluded that, there is association between Maternal health with obstetrical history of mother with type of delivery and condition of baby at birth. Hence, maternal health has influence the obstetrical history of mothers.
Effectiveness of Structured Teaching Programme on Knowledge regarding the Prevention and Management of Covid-19 among Housewives in selected area of Alappuzha District in Kerala, India
Authors: Clement Nahomi , Jose Smitha
Published: October 2023

The Coronavirus disease (COVID-19) is an infectious disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It has been recognized as a pandemic by WHO, and the rate is succeeding in day by day as mostly as community spread. Even though the invention of vaccines has a great result, we must continue the essential public health actions to suppress transmission and reduce mortality. The purpose of the study is to identify the effectiveness of structured teaching programme on knowledge regarding the prevention and management of covid-19 among housewives in selected areas of Alappuzha district in Kerala. The research method adopted for this study is an interventional study of one group pretest posttest type was design. The study group consists of 50 housewives selected by convenient sampling technique. The researcher assessed the knowledge regarding the prevention and management of COVID-19 using a structured knowledge questionnaire followed by a structured teaching programme. The study revealed that on pretest only 44% of samples had a good knowledge, 30% had average knowledge and 26% had poor knowledge whereas during the posttest all the samples scored good knowledge level. The study revealed that the structured teaching programme was effective in improving the knowledge score among the housewives. The study pointed out a clear need for training programme with respect to a specific cluster of population emplaning upon their respective lifestyle, to improve the knowledge and compliance about risk and preventive measures. As a nursing professional, we have a crucial role creating awareness by innovative ways which should be adopted as one of the best practices to combat the spread of pandemic.