bluuebunny/crossref_metadata_2025 huggingface dataset:
El desarrollo organizacional en los tiempos de la post pandemia.
Authors: Espino Castillo Damián
Published: August 2023

El presente trabajo es un intento de conocer y resaltar los cambios y los procesos organizacionales, que se han generado en el período post pandemia y cómo estos han influido en el desarrollo de los negocios empresariales en general. Hicimos una revisión de toda la literatura disponible y a nuestro alcance, que nos pudiera servir para interpretar, por un lado, el significado y valor del Desarrollo Organizacional (DO) en estrategias empresariales, dirigidas al mejoramiento de los procesos productivos y de servicios, y por la otra, cómo el DO fue una herramienta vital para que muchas empresas, pudieran sobrevivir durante la etapa pandémica; y ahora,  cuando la contingencia de salud pública comienza a ser superada, se vuelve una pieza fundamental para encontrar e identificar los cambios y las transformaciones, que han demostrado su pertinencia en las nuevas realidades que se han venido configurando. El período post pandemia ha puesto de manifiesto que tanto las empresas como las organizaciones, deben concederle una alta prioridad al fortalecimiento del liderazgo, del compromiso de sus empleados con sus valores y objetivos de los negocios, así como fomentar la responsabilidad social, la protección del ambiente, la integración en equipo, donde la motivación y la comunicación sean firmes baluartes. El papel decisivo de la incorporación constante de la tecnología y las plataformas digitales para facilitar, entre cosas, el comercio electrónico, constituye una de las principales conclusiones de este trabajo.
Cell based models for validation of safety of cosmetic products and ingredients
Authors:   Research and Development center, Himalaya Wellness Company, Singh Nikhil
Published: August 2023

The use of cosmetic products has grown many folds in recent years. The consumer and regulatory bodies are more concerned about the hazardous outcome of these products on skin health. The development of alternative and effective safety assessment methodologies to avoid animal testing is an urgent need due to restrictions and ethical considerations set by various regulatory bodies such as OECD, COLIPA, and BIS. The new integrated approaches like in-vitro assays (Cell-based and Cell-free assays) are indispensable for assessing the safety of cosmetic products. In-vitro testing systems provide advantages over animal testing as they are more cost-effective, and less time-consuming. In this article, we present the details of some of the important invitro assays that are routinely used by different laboratories for validation of the safety of cosmetic ingredients.
Antibacterial activity of stem bark extract of traditionally used Terminalia bellirica (Gaerth.) Roxb.
Authors:   Department of Chemistry, S.G.R.R. Post Graduate College, Dehradun –UK, India, Vir Singh Shyam , Kumar Naveen ,   Department of Chemistry, K. L. D.A.V. Post Graduate College, Roorkee-UK, India, Singh Ankita ,   Post Graduate Department of Agad Tantra, Rishikul Campus, U.A.U, Haridwar, UK, India, Jangwan J.S. ,   Department of Chemistry, HNB Garhwal University, Campus Badshahi Thaul, Tehri -UK, India
Published: August 2023

Medicinal Plants have been practised for hundreds of centuries by tribes all over the world. From the earliest times until the end of nineteenth century plants are still the common source of medicinal treatment yet. Using natural, plant-derived medicines that are “healthier” than prescription drugs derived from synthesized products is something that appeals to consumers. In this study, the plant Terminalia bellirica was taken for study due to the mesmerizing medicinal properties of the plant. The antibacterial activities of acetone, ethyl acetate, benzene and methanol extracts of Terminalia bellirica stem bark were tested for four pathogenic bacterial strains by agar disc diffusion method. Among the various extract, acetone extracts showed good antibacterial activity and maximum zone of inhibition was obtained for Staphylococus aureus (zone size 8mm) followed by Pseudomonas aurogenosa (10mm). The results are given in Table-1. Methanol extract showed antibacterial activity against E. coli (zone size 8mm). On the other hand ethyl acetate and benzene extract was found to be totally unaffected against these bacterial strains.
Primary and secondary metabolites identification in Hamelia patens leaves
Authors:   D.A.V (PG) College, Muzaffarnagar, India, Tyagi Shweta , Kumar Ashish ,   D.A.V (PG) College, Muzaffarnagar, India, Garg Ashish ,   Department of Chemistry, Seth N.M.T. Girls (PG) College,  Jhunjhunu, Rajasthan, India, Pandey I.P.
Published: August 2023

The aim of the present study was to investigate the presence of phytochemicals in leaves extracts (aqueous, methanol, ethanol) of Hamelia patens, the selected medicinal plant. Ethanolic and methanolic (organic) extract showed good number of compounds compared to aqueous extracts. Phyto-chemical analysis of organic extracts of Hamelia patens has shown the biological compounds like protein and amino acids, carbohydrates, cardiac glycosides, tannin, phenol, alkaloids, steroids, terpenoids, flavonoides and saponin. Quinones, phlobatannins, coumarins, emodins and fatty acids were absent in both the aqueous and organic extracts.
Phytochemical screening and antimicrobial activity of Aerva lanata (Gorakh ganja)
Authors:   Himalaya Wellness Company, Faridabad, India, Azim Beg Mirza , Ali Ragib ,   Himalaya Wellness Company, Faridabad, India, suddin Rahi ,   Himalaya Wellness Company, Faridabad, India
Published: August 2023

Aerva lanata is a perennial shrub which belongs to the family Amaranthaceae and is found throughout tropical India as a weed in the fields and wasteland area. This plant is a good source of phytochemicals like terpenoids, flavonoides, alkaloids, phenolic compounds, glycosides, gums, tannins, terpenes, carbohydrates and amino acids. Other chemical constituents of Aerva lanata include ferulic acid, syringic acid, narcissin and feruloyl tyramine etc which are responsible for their antibacterial, antifungal, antioxidant, anti-asthmatic and anthelmintic activities. The result of phytochemical study shows that the alcoholic extract of Aerva lanata contains alkaloids, saponins, tannin, polyphenolic compound, amino acid, proteins, flavonoids, steroids, cardio glycosides, terpenoids and carbohydrate and it can be mentioned that the alcoholic extract of Aerva lanata contains higher number of phytochemicals as compared to all other extract of Aerva lanata studied in the present investigation. The MIC of the different extracts of Aerva lanata was found in the range of 25 µl to 45 µl. The different extracts of Aerva lanata shows antimicrobial activity against tested microorganism with inhibition zone ranging from 22 mm to 24 mm. The ethanol extract of Aerva lanata shows maximum zone of inhibition and is comparable or better than standard drug against all tested microorganisms.
Pengembangan Handout Berbasis Qr Code
Authors: Winarni Dwi Fitri
Published: August 2023

Penelitian ini bertujuan untuk mengembangkan handout yang memiliki keterbatasan halaman namun mampu menjelaskan topik secara luas melalui pencantuman qr code pada materi hidangan kesempatan khusus untuk acara adat istiadat. Penelitian ini merupakan penelitian research and development (R&D) yang menggunakan model pengembangan Four-D dari Thiagarajan dan Semmel. Tahapan yang dilakukan meliputi define, design, develop, dan disseminate. Define, tahapan cara menganalisis pembelajaran, peserta didik, konsep, tugas dan spesifikasi tujuan pembelajaran. Design, tahapan dalam menghasilkan prototype produk yang akan dikembangkan. Develop merupakan tahap pengembangan untuk mengembangkan prototype handout berbasis qr code hingga valid dan layak dipakai. Disseminate, tahapan untuk mengetahui efektifitas pengembangan handout disebarkan secara luas. Metode pengumpulan data melalui instrumen hasil validasi ahli, observasi, wawancara, dan hasil tes tertulis. Data dianalisis melalui teknik  triangulasi sumber, teknik, dan waktu. Hasil penelitian menunjukkan berdasarkan validasi ahli IT diperoleh skor 39 terletak pada interval 45 > X ≥ 37,5, ahli media diperoleh skor 42 terletak pada interval 45 > X ≥ 37,5, ahli materi diperoleh skor 53 terletak pada interval X ≥ 45, validasi guru mata pelajaran diperoleh skor 52 terletak pada interval X ≥ 45, respon peserta didik diperoleh skor 50,1 terletak pada interval X ≥ 45. Kesimpulan hasil penelitian dan pengembangan melalui R & D model 4-D handout berbasis qr code dalam kategori layak digunakan sebagai media pembelajaran dan mampu meningkatkan prestasi belajar.
Optimalisasi Flipped Classroom untuk Meningkatkan Keaktifan dan Kemampuan Menyelesaikan Soal-Soal HOTS Procedure Text
Authors: Latifah Nusroh
Published: August 2023

Penelitian ini dilatarbelakangi kemampuan peserta didik menyelesaikan soal HOTs  masih rendah, terlihat dari rata-rata  perolehan nilai dari soal HOTs pada materi sebelumnya kurang dari kriteria ketuntasan minimal. Penelitian ini bertujuan untuk meningkatkan kemampuan menyelesaikan soal-soal HOTS procedure text melalui pembelajaran flipped classroom. Model penelitian yang digunakan mengadopsi dari Kemmis dan Taggart dengan 2 siklus dan 2 pertemuan untuk setiap siklusnya. Model pembelajaran ini diimplementasikan melalui tiga tahap, yaitu before class, during class, dan after class dalam setiap pertemuannya. Data diperoleh dengan menggunakan instrumen lembar observasi kinerja guru, lembar observasi keaktifan peserta didik, catatan lapangan, wawancara, dan instrumen tes, serta dianalisis secara deskriptif kualitatif dan kuantitatif. Hasil observasi menunjukkan peningkatan keaktifan peserta didik dalam pembelajaran pada setiap pertemuan dan peningkatan hasil dari pretest ke postest pada setiap siklus serta peningkatan hasil postes dari siklus 1 ke siklus 2 (71.88% pada siklus 1 dan 87.50% pada siklus 2). Berdasar uraian tersebut dapat disimpulkan bahwa pembelajaran flipped classroom dapat meningkatkan kemampuan menyelesaikan soal-soal yang memerlukan keterampilan berpikir tingkat tinggi (HOTS) dari procedure text.
The Role of Africa’s Moral Education in Environmental Care for Socio-economic Development in Contemporary Society
Authors: Buya Carolyne S. Mudeje , Katam Elizabeth J.
Published: August 2023

This paper examines African moral education and its role in environmental care for Socio economic development in Africa. This is informed by the observation that the moral system in African society permeated every aspect of life and viewed economic development in the light of human welfare. African cultural heritage has human welfare at its core and is not limited to people in actual existence but those departed too, yet believed to reside in nature. As such, care for the environment was part and parcel of people’s beliefs as informed by the interrelated nature of every component that constitutes the universe. The paper begins by exploring the key elements of indigenous African moral education and how it impacted environmental responsibility and development initiatives in the various communities. A reasonable way forward for enhancing environmental care for socio-economic development in contemporary Africa, through learning institutions, is advanced. This paper is theoretical in nature but will also make reference to actual scenarios in society in order to substantiate any claims made. The philosophical method of analysis, and evaluation of documented information has been utilized.
Safeguard patient safety in a refugee crisis
Authors: Gelinas Lillee
Published: August 2023

A call for nursing action in the face of a crisis that threatens refugee health and safety.
Proper documentation protects patients and your license
Authors: Hankey Laura
Published: August 2023

Erroneous and incomplete documentation presents real risks to your patients and your career.
Analysis of Education Policy on the Implementation of Post-Covid-19 Distance Learning
Authors: Oktiarina Vina , Syarifudin Encep , Suherman Suherman
Published: August 2023

Learning is a central aspect of the educational process essential in transferring knowledge and skills to individuals. However, when obstacles are caused by situations and conditions that do not allow direct/face-to-face learning in the classroom, then learning can be implemented online. Through the digital platform, teachers and students can connect virtually, cross the boundaries of distance and time, and utilize technology to learn. This research analyzes educational policies on implementing distance learning after Covid-19 to see the various problems faced. This research uses a qualitative method with a literature study approach. Data analysis will be carried out through selecting, comparing, combining, and sorting out various definitions, until relevant ones are found, and to overcome misinformation or avoid errors, inter-literature checking and re-reading of literature are carried out. The result of this research is that the implementation of distance learning is still faced with various obstacles. These constraints include limited social interaction between teachers and students, limited learning services that can be provided, the need for understanding the use of learning applications, internet-related constraints, and the economy. This research shows the need for efforts to overcome these obstacles so that distance learning can run more effectively and evenly.
MEDICAL AID AND RESEARCH PROJECTS FROM NAGASAKI ON RADIATION HEALTH EFFECTS AROUND CHERNOBYL
Authors: Yamashita S.
Published: August 2023

The medical cooperative projects from Nagasaki to the former USSR have been performed in mainly two regions: Chernobyl and Semipalatinsk since 1990 and 1995, respectively. What we should do here in Nagasaki and also from Nagasaki will be discussed at the standpoint of humanitarian medical aid and scientific research collaboration usinsgt different channels of governmental and non-governmental cooperative linkages. The 21st Center of Excellence (COE) program of «International Consortium for Medical Care of Hibakusha and Radiation Life Science» established in Nagasaki University can serve our knowledge and experience much more directly in relation to the radiocontaminated areas in the world, and indeed contribute to the lessons learned from Chernobyl and also to the newly establishme of Network of Excellence (NOE) for Radiation Emergency Medicine under the auspices of the WHO-REMPAN. Within the frame of the International Consortium of Radiation Research, a molecular epidemiology of thyroid diseases has now been conducted in our departments. The clue of radiation-associated thyroid carcinogenesis may give us a new concept on experimental and epidemiological approaches to low dose radiation effects on human health, including internal radiation exposure.
THE REMOTE RESULTS OF THE COMBINED OPERATIONS WITH THE PANCREATECTOMY FOR GASTRIC
Authors: МИХАЙЛОВ И.В. , ГОЛУБЕВ О.А. , АЧИНОВИЧ С.Л. , БОНДАРЕНКО В.М.
Published: August 2023

The remote results of 110 combined operations with distal or proximal pancreatectomy for locally advanced gastric cancer (GC) are investigated. The observable five years' survival rate of all patients was 30,1%, a median of survival rate - 28,6 months. 16,4% of patients had residual tumour, its presence was the major factor of the prognosis, the median of survival rate was 4,0 months in the this group. At diffuse GC five years' survival rate of patients were lower, than at intestinal - 16,3% vs. 36,6% (p<0,05). Expansion lymph node dissection was accompanied by increase of survival rate of patients. Adjuvant chemotherapy sharply raised life expectancy of those patients who have transferred palliative resections.
THE PROBLEM IN THE REABILITATION OF PATIENTS, OPERATED BY THYROID CARCINOMA
Authors: Savasteeva I.G. , Makarchic A.V. , Beresneva S.M , Bronskaya K.V , Yanucovich E.Z.
Published: August 2023

In this article are discussed questions of quality of postoperative conducting patients, concerning thyroid carcinoma. Questions of a ТБН medicaments suppression in various years after operative treatment, and also a Phosphorus and Calcium condition and degree of it correction was discussed.
IODINE PROVISION OF PERSONNEL OF POLESYE STATE RADIATION ECOLOGICAL RESERVE
Authors: Lektorov V.N , Zhavoronok S.V , Naumov A.D. , Kalinin A.L , Sergeichick N.L. , Vlasova N.G , Platoshkin E.N , Romankov L.V , Visenberg Yu.V.
Published: August 2023

The aim of the study is to evaluate the degree of iodine provision of personnel of Polesye State Radiation Ecological Reserve constantly living and working on the radionuclides-contaminated territories of Bragin and Hoiniki districts of Gomel region. Statistic analysis of experimental data of the amount of iodine in the urine sampling of the PSRER staff has shown the lognormally distributed character of the iodine. Average amount of iodine in the urine of PSRER staff is 204,1mcg/l with errors 5% below and 11% above which by ICCIDD norms is not considered as iodine insufficiency and does not suggest any preventive measures.
CONDITION OF LIPID METABOLISM IN PATIENTS WITH CEREBRAL INFARCTION
Authors: Latysheva V. Ya. , Al Khulaidi Mohamed A.s
Published: August 2023

Lipid metabolism disorder, lipid infiltration results in lipoprotein deposition in intercellular space, and the concentration of cholesterol ethers, mediators of inflammation in walls of vessels, promotes their atherosclerotic affection and development of cardiac and cerebrovascular diseases. Research articles in this field are not numerous and sometimes contradictory. This paper represents the results of the investigation of the lipid spectrum of blood serum of patients with cerebral infarction. A reliable increase of several indicators of the lipid spectrum (cholesterol, low-density lipoproteins, triglycerides, and atherogenity coefficient) is detected as compared with the control data. The amount of high-density lipoproteins significantly did not differ from the control data.
FORECASTING OF THE OPPORTUNITY OF PERFORMANCE SIMULTANEOUS OPERATIONS FOR PATIENTS WITH ACUTE CHOLECYSTITIS
Authors: Osipov B. B.
Published: August 2023

Influence of various factors (a sex, age, duration of surgery, visual pathological changes in an abdominal cavity, laboratory parameters) on development of purulent complications in the early postoperative period of patients with an acute cholecystitis after simultaneous operations is analysed. Two groups of patients with complicated (n = 10) and not complicated (n = 135) postoperative period are analysed and the tree of decisions is constructed and contraindications for performance of simultaneous operations are developed.
SOCIAL RISK FACTORS OF ENTEROBIASIS AT CHILDREN VISITING PRESCHOOL ESTABLISHMENTS OF GOMEL
Authors: Butenkova E. M.
Published: August 2023

Social risk factors of enterobiasis at children visiting preschool establishments of Gomel are investigated. The most significant factors increasing risk of pinworm infection are the age of the child of more than 2 years, quantity of children in family - 2 and more, living together of children in a children's room, and also factors of hygienic education: default of rules to use an individual towel, to wash hands before meal, and to use boiled drinking water.
EFFECACY OF THE TREATMENT IN PATIENTS WITH ORAL MUCOSA EROSIVE-ULCEROUS LESIONS WITH MEDICINES ON BIENUM BASIC
Authors: Feodorova I. N.
Published: August 2023

The purpose of this research was to study the efficiency of applying medicines on Bienum basic (complex ethylene ethers of polyunsaturated fatty acids by microbiological origin) in patients with oral mucosa erosive-ulcerous lesions. The efficacy of application medicines on Bienum basic (ointment «Reparaef-1» and «Reparaef-2») was defined on clinical examination of patients. There was determined that Bienum increases oral mucosa regeneration and decreases the term of healing oral mucosa erosive-ulcerous lesions (p < 0,05). Also medicines on Bienum basic possess the unti-inflammatory effect, painkiller acting.
GENETIC DAMAGES IN BLOOD CELLS UNDER COMBINED RADIATION - TOXIC ACTION. THE ROLE OF DOSE RATE
Authors: Sushko S. N. , Malenchenko A. F. , Ferapontova N. A.
Published: August 2023

Combined influence of single or prolonged γ-irradiation 0,35 Gy (dose rate 1 Gy/h and 0,008 Gy/h) and urethan on the induction of chromosome aberrations (ChA) in bone marrow cells and micronucleus (MN) in peripheral blood polychromatic erythrocytes and also γ-irradiation, urethane, nitrogen dioxide on the induction of lung adenoma were studied. Correlation between the ratio of exchange type ChA and dose rate was of inverse direction. The lung adenoma frequency under combined action in the case of prolonged irradiation with low dose rate was increase that correlate with exchange type ChA.
CLINICO-MORPHOLOGICAL FEATURES OF LUNG CANCER IN POPULATION OF GOMEL REGION
Authors: Doroshenko R. V. , Golubev O. A. , Achinovich S. L.
Published: August 2023

Over the last recent years the lung cancer has been a subject to scrutinize by doctors and investigators of many fields. At present, lung cancer rates the first both within the general structure of oncological diseases and reasons of mortality of the world’s population, especially in males.
MORPHOEPIDEMYOLOGY OF STOMACH CARCINOMA AND POLYPS IN THE REGIONS OF REPUBLIC OF BELARUS WITH DIFFERENT LEVELS OF RADIOACTIVE CONTAMINATION
Authors: Krylov Y. V. , Medvedev M. N. , Zhavoronok S. V.
Published: August 2023

The study of Cs 137 accumulation in the autopsy material by the gamma-spectrometric was performed in Vitebsk and Gomel regions. The accumulation of Cs 137 in autopsy material was more severe in Vitebsk region. Stomach carcinoma and polyps, diagnosed by the fibrogastroscopia in Vitebsk and Gomel regional clinical hospitals, were investigated. There were no age and sex differences in the structure of morbidity, and correlation of histological forms of stomach carcinoma and polyps in this hospitals.
QUANTITY ANALYSIS OF RAT BLOOD LEUCOCYTE SYSTEM CELLS AND LYMPHOCYTES METABOLIC ACTIVITIES AT ALLOXANE DIABETE, LOW-DOSE IRRADIATION AND SELEXENE APPLICATION
Authors: Konoplya E. F. , Andronova E. V. , Vereshchako G. G.
Published: August 2023

It was investigated rat blood leucocytes system cells status and lymphocytes metabolic activity at diabetes induced by alloxane (80 mg/kg) in condition of irradiation at dose 1,0 Gy and selexene application. In initial period after irradiation and alloxane administration it was marked decreasing of leucocytes amount induced by death lymphocytes in rat blood. More changes of studied parameters it was remarked it irradiation on both non-diabetic and diabetic animals. Activities of blood lymphocytes dehydrogenases (LDH, SDH) was increased first of all in the first place at the combined action of alloxane and irradiation. Selexene aid positive effect on сells leucocyte system of diabetic rats at 3 and 10 day after irradiation.
An Overview of the Developments in the Discipline of Human Rights
Authors: Agarwal Dr. Anita
Published: August 2023

Human rights must be maintained and made available to everyone since they are necessary for the whole development of each person's individuality within society. The inevitable expansion of government control over people's behaviour has led to a demand for protection, which is in no way to be viewed as beneficial. The realisation that all laws, whether they are rules of municipal law or that of international law, should have as their purposes the protection of human rights in the interest of humanity was brought about by people's realisation that their rights also required the protection by states. All people have the same basic legal rights, regardless of their gender, colour, nationality, ethnicity, language, religion, or any other distinction. Human rights cover a wide range of rights, such as the freedom from slavery and torture, the right to life and liberty, the freedom of speech, the right to a job and an education, among many more. These rights apply to everyone without exception.
CONVULSÕES NEONATAIS: UMA DIFICULDADE CLÍNICA NEONATAL
Authors: Martins Camila Hassen , Pereira Karen Mendes
Published: August 2023

INTRODUÇÃO: As convulsões neonatais são caracterizadas como patologias neurológicas e estão entre as mais frequentes deste período, ocorrendo e até 1,4% dos recém-nascidos e até 20% dos prematuros. OBJETIVO: Realizar uma revisão da literatura no que tange ao melhor entendimento acerca das crises convulsivas neonatais, procurando destacar sua importância, assim como suas principais características e desafios no cenário atual. METODOLOGIA: A atual pesquisa é caracterizada como uma revisão narrativa de literatura, de abordagem qualitativa do tipo descritivo-exploratórias. RESULTADOS E DISCUSSÃO: As crises convulsivas neonatais possuem taxa de mortalidade de 20%, podendo gerar diversas consequências como epilepsia, déficits psicomotores, paralisia cerebral e certo atraso no desenvolvimento cerebral da criança. CONCLUSÃO: A utilização de medicamentos antigos ainda recebe destaque, porém novas drogas estão cada vez ganhando mais espaço à medida que novos estudos estão sendo desenvolvidos para comprovar a eficácia e segurança destes.
PERFIL DE INTERNAÇÕES POR INSUFICIÊNCIA CARDÍACA NO MUNICÍPIO DO RIO DE JANEIRO NO ANO DE 2021
Authors: Silva Danilo Vitorio Marques da , Oliveira  Vinícius Loures de , Oliveira Vinicius Gomes Alves de , Cameranto Neto Helio Speranza , Moore Mario Alberto do Valle Rocha , Abbud Luis Felipe Holzwarth , Ferreira Rodrigo El Ajouze Barbosa , Souza Viviane Fernandes Marques de
Published: August 2023

A Insuficiência Cardíaca (IC) apresenta alta prevalência e incidência no Brasil, respectivamente, com 2 milhões de pacientes acometidos pela síndrome e com aproximadamente 250.000 casos novos todos os anos. Assim, o objetivo do presente trabalho é descrever, qualitativamente e quantitativamente, o perfil epidemiológico por IC no município do Rio de Janeiro no ano de 2021. Trata-se de um estudo com desenho observacional e ecológico, com análise epidemiológica e estatística descritiva, tendo como base de dados para pesquisa o Sistema de Informações Hospitalares do SUS (SIH-SUS), do Ministério da Saúde. Os filtros utilizados para a pesquisa foram município da internação, sexo e faixa etária, agrupando os pacientes conforme a maior prevalência no ano pesquisado para cada um dos filtros utilizados. Por se tratar de um estudo com dados públicos, a análise por Comitê de Ética em Pesquisa (CEP) foi dispensada. Com os dados obtidos, foi observado uma taxa total de internações por IC, no município analisado, de 27,2 a cada 100.000 habitantes. Quando analisado por sexo, o sexo feminino apresentou taxa total de 23,6 a cada 100.000 habitantes, enquanto o sexo masculino apresentou taxa total de internações por IC de 31.1 a cada 100.000 habitantes. O total de internações por IC tem crescido em todo o Brasil nos últimos anos. Com os resultados, conclui-se que homens apresentam maior taxa de internações por IC no município analisado, variando conforme grupo de faixa etária. Novos estudos são necessários para melhor compreensão dos fatores etiológicos que causam maior taxa de internações por IC em homens não somente no município analisado, mas no Brasil como um todo.
VARÍOLA DOS MACACOS: NOVA AMEAÇA PANDÊMICA? IMUNOLOGIA E DIAGNÓSTICO DO VÍRUS
Authors: Alves Ana Vitória Gomes , Fernandes Alejandro Pereira , Pinheiro Ariane Gleyse Azevedo , Santos Gabriel Victor Moreira
Published: August 2023

Foi declarada emergência de saúde pública de interesse internacional pela Organização Mundial da Saúde em 23 de julho de 2022, para o vírus da varíola dos macacos. É uma zoonose viral que pode ser transmitido por contato direto ou indireto, sendo mais incidentes em hospedeiros imunocomprometidos e em gestantes a suscetibilidade é maior. Porém para os indivíduos vacinados anteriormente contra a varíola, foi descrito que pode haver a imunidade contra a varíola dos macacos pela proteção cruzada. Esta pesquisa teve como objetivo descrever as características da relação patógeno-hospedeiro e diagnóstico, elementos componentes para o estudo da estruturação da resposta no combate a pandemia. Esse estudo se baseia numa revisão de literatura, no qual ocorre a busca e análise dos artigos de interesse. Foram selecionados 15 artigos que estiveram com a temática escolhida para serem avaliados na revisão. A apresentação clínica descrita consiste em febre, linfadenopatia e exantema papulopustuloso. A erupção passa por vários estágios de evolução de máculas, pápulas, vesículas, pústulas e crostas. A investigação de um caso suspeito deve incluir exames complementares para fazer o diagnóstico diferencial com algumas infecções sexualmente transmissíveis e causas comuns de exantema maculopapular ou vesicular. No Brasil, pacientes suspeitos devem ter amostras coletadas para confirmação diagnóstica por reação de cadeia de polimerase, os testes sorológicos são úteis em situações especificas, quando não há possibilidade de utilizar amostra virológica, mas podem fornecer resultados falso-positivos em pessoas vacinadas contra varíola. Como não há tratamento específico, para a maioria dos pacientes, o tratamento é sintomático e de suporte. Atualmente, é necessário direcionar as ações para promoção de métodos eficazes de vigilância epidemiológica e crescente adequação do sistema único de saúde para o diagnóstico e tratamento oportuno.
REALIDADE VIRTUAL APLICADO AO ENSINO DE BIOLOGIA: UM RELATO DE EXPERIÊNCIA EM UMA ESCOLA PÚBLICA DE ENSINO MÉDIO DO ESTADO DO AMAZONAS
Authors: Santos Amanda Silva dos , Menezes Antonia Thainá Carneiro de , Paulino Marlon Ponciano , Santos Everton Oliveira dos , Antunes Franciano
Published: August 2023

O artigo apresenta o trabalho realizado no âmbito do Estágio Supervisionado em Computação II do Curso de Licenciatura em Computação. Desta forma, justifica-se em demonstrar como o licenciando foi inserido no ensino. O presente trabalho classifica-se como uma pesquisa experimental, uma vez que os alunos e os professores são objetos de estudo. No primeiro momento realizou-se a observação das aulas ministradas pela professora, para identificação dos conteúdos que os alunos tivessem mais dificuldades. Após identificação desse conteúdo foi realizado um planejamento todo baseado no conteúdo de células que os alunos, mas tinham dificuldade de aprendizado. Assim, concluiu-se que durante as aulas práticas, o desenvolvimento, participação e atenção dos alunos era maior do que nas aulas apenas expositivas, por este motivo a Realidade Virtual foi utilizada como proposta de auxiliar no aprendizado, aumentando o engajamento e tornando o aprendizado mais efetivo e prazeroso.
REAGUDIZAÇÃO DE LESÃO PERIAPICAL EXTENSA: RELATO DE CASO
Authors: Travassos Rosana Maria Coelho , Cardoso Maria do Socorro Orestes , Melo Júnior Paulo Maurício de Reis , Pontes Mônica Maria de Albuquerque , Carneiro Vanda Sanderana Macêdo , Cavalcanti Marcela Rosa Nogueira
Published: August 2023

O objetivo deste trabalho é descrever um relato de caso de uma reagudização de uma lesão periapical extensa ocorrido com uma paciente tratada na Clínica de Atenção Básica II (CAB-II) da Faculdade de odontologia de Pernambuco (FOP). Após exame clínico e radiográfico o diagnóstico provável foi de granuloma periapical no dente 11. Realizou-se a abertura coronária com brocas esféricas, de acordo com a técnica coroa-ápice utilizou-se brocas Gattes Glidden em ordem decrescente e em seguida limas manuais até o comprimento real do instrumento. Concluída essa fase, foi feita a radiografia de odontometria. Prosseguiu-se com o preparo apical até a lima de número 90. A cada troca de lima foi feita irrigação com 5ml de hipoclorito de sódio a 2,5% e com a lima 15 realizou-se a patência foraminal. Foi feita medicação intracanal a base de Hidróxido de cálcio (ultracal®), e o selamento com ionômero de vidro. Quatro dias após início do tratamento endodôntico a paciente relatou febre e dor. Clinicamente observou-se um aumento de volume na região palatina. Esse processo inflamatório recebeu diagnóstico de flare-up ou abscesso fênix. Para resolução do caso removeu-se o selamento coronário, foi feita irrigação, introdução do Ultracal® e novo selamento coronário. Em seguida, realizou-se a drenagem da coleção purulenta com o auxílio de lâmina de bisturi de número 15-C. Prescreveu-se terapia antibiótica, analgésica e antitérmica. Uma semana depois a paciente retorna a clínica apresentando melhora do processo inflamatório e ausência de sintomatologia.  Dessa maneira, conclui-se que é necessário realizar uma penetração desinfectante mais cuidadosa evitando-se o desequilíbrio da flora bacteriana e o desenvolvimento de abscesso fênix a partir da reagudização de uma lesão periapical.
Matériaux pour le stockage thermochimique et par sorption
Authors: N’TSOUKPOE Kokouvi Edem
Published: August 2023

Le stockage thermique par sorption ou par voie thermochimique utilise des phénomènes mettant en jeu un gaz en contact avec un matériau liquide, solide ou gazeux. Après une introduction du principe de stockage thermique sous forme de potentiel chimique et des caractéristiques des matériaux susceptibles d’y convenir, ce chapitre donne un aperçu des matériaux les plus utilisés dans ce domaine.
Estimating nitrogen and sulfur deposition across China during 2005 to 2020 based on multiple statistical models
Authors: Zhou Kaiyue , Xu Wen , Zhang Lin , Ma Mingrui , Liu Xuejun , Zhao Yu
Published: August 2023

Abstract. Due to the rapid development of industrialization and a substantial economy,
China has become one of the global hotspots of nitrogen (N) and sulfur (S)
deposition following Europe and the USA. Here, we developed a dataset with
full coverage of N and S deposition from 2005 to 2020, with multiple
statistical models that combine ground-level observations, chemistry
transport simulations, satellite-derived vertical columns, and
meteorological and geographic variables. Based on the newly developed random
forest method, the multi-year averages of dry deposition of oxidized
nitrogen (OXN), reduced nitrogen (RDN), and S in China were estimated at
10.4, 14.4, and 16.7 kg N/S ha−1 yr−1, and the analogous numbers
for total deposition were respectively 15.2, 20.2, and 25.9 kg N/S ha−1 yr−1 when wet deposition estimated previously with a generalized
additive model (GAM) was included. The dry to wet deposition ratio
(Rdry/wet) of N stabilized in earlier years and then gradually increased
especially for RDN, while that of S declined for over 10 years and then
slightly increased. The RDN to OXN deposition ratio (RRDN/OXN) was
estimated to be larger than 1 for the whole research period and clearly
larger than that of the USA and Europe, with a continuous decline from 2005 to 2011 and a more prominent rebound afterwards. Compared with the USA and
Europe, a more prominent lagging response of OXN and S deposition to
precursor emission abatement was found in China. The OXN dry deposition
presented a descending gradient from east to west, while the S dry
deposition a descending gradient from north to south. After 2012, the OXN
and S deposition in eastern China declined faster than the west,
attributable to stricter emission controls. Positive correlation was found
between regional deposition and emissions, while smaller deposition to
emission ratios (D/E) existed in developed eastern China, attributed to more
intensive human activities and thereby anthropogenic emissions.
Current status of model predictions on volatile organic compounds and impacts on surface ozone predictions during summer in China
Authors: She Yongliang , Li Jingyi , Lyu Xiaopu , Guo Hai , Qin Momei , Xie Xiaodong , Gong Kangjia , Ye Fei , Mao Jianjiong , Huang Lin , Hu Jianlin
Published: August 2023

Abstract. Volatile organic compounds (VOCs) play a crucial role in the formation of tropospheric ozone (O3) and secondary organic aerosols. VOC emissions are generally considered to have larger uncertainties compared to other pollutants, such as sulphur dioxide and fine particulate matter (PM2.5). Although predictions of O3 and PM2.5 have been extensively evaluated in air quality modelling studies, there has been limited reporting on the evaluation of VOCs, mainly due to a lack of routine VOCs measurements at multiple sites. In this study, we utilized VOCs measurements from the ATMSYC project at 28 sites across China and assessed the predicted VOCs concentrations using the Community Multiscale Air Quality (CMAQ) model with the widely used Multi-resolution Emission Inventory for China (MEIC). The ratio of predicted to observed total VOCs was found to be 0.74 ± 0.40, with underpredictions ranging from 2.05 to 50.61 ppbv (5.77 % to 85.40 %) at 24 sites. A greater bias in VOCs predictions was observed in industrial cities in the north and southwest, such as Jinan, Shijiazhuang, Lanzhou, Chengdu, and Guiyang. In terms of different VOC components, alkanes, alkenes, non-naphthalene aromatics (ARO2MN), and alkynes were consistently underpredicted, with prediction to observation ratios of 0.53 ± 0.38, 0.51 ± 0.48, 0.31 ± 0.38, and 0.41 ± 0.47, respectively. Sensitivity experiments were conducted to assess the impact of the VOCs prediction bias on O3 predictions. While emission adjustments improved the model performance for VOCs, resulting in a ratio of total VOCs to 0.86 ± 0.47, they also exacerbated O3 overprediction relative to the base case by 0.62 % to 6.27 % across the sites. This study demonstrates that current modelling setups and emission inventories are likely to underpredict VOCs concentrations, and this underprediction of VOCs contributes to lower O3 predictions in China.
Observability of Moisture Transport Divergence in Arctic Atmospheric Rivers by Dropsondes
Authors: Dorff Henning , Konow Heike , Schemann Vera , Ament Felix
Published: August 2023

Abstract. This study emulates dropsondes to elucidate how adequately sporadic airborne sondes represent divergence (convergence) of moisture transport in arctic Atmospheric Rivers. The convergence of vertically integrated moisture transport (IVT) plays a crucial role as it favours precipitation that significantly affects arctic sea ice properties. Long range research aircraft can transect ARs and dropsondes determine their IVT divergence. However, a limited number of sondes may deteriorate the representation of IVT variability and divergence. We disentangle errors arising from undersampling by discrete soundings and from the flight duration in order to assess the representativeness of future sonde-based IVT divergence in arctic ARs. Our synthetic study uses CARRA reanalyses to set up an idealised scenario for airborne AR observations.For nine arctic spring ARs, we mimic flights transecting each AR in CARRA and emulate sonde-based IVT representation by picking single vertical profiles. The emulation quantifies IVT divergence observability by two approaches. First, sonde-based IVT and its divergence are compared to the continuous IVT interpolated onto the flight cross-section. The comparison specifies uncertainties of discrete sonde-based IVT variability and divergence. Second, we determine how temporal AR evolution affects IVT divergence values by contrasting time-propagating sonde-based values with the divergence based on instantaneous snapshots. For our arctic AR cross-sections, we find that moisture transport variability contributes less than 10 % to its lateral mean, while wind and moisture variability individually are higher. Both quantities can be uncorrelated and do not consistently exhibit a coherent pattern. Moisture turns out as the more varying quantity. We show that sounding spacing greater than 100 km results in errors greater than 10 % of the total IVT along AR cross-sections. For IVT divergence, the arctic ARs exhibit similar gradients in moisture advection and mass convergence across the embedded front as mid-latitude ARs, but we identify moisture advection being dominant. We overall confirm their observability with an uncertainty lower than 25 % by a sequence of at least seven sondes per cross-section. Rather than sonde undersampling, it is the temporal AR evolution over the flight duration that leads to higher deviations in divergence components. Dedicated planning of sonde-based IVT divergence purposes should not only involve sonde positioning but rather pursue optimizing the flight duration. Our benchmarks quantify sonde-based uncertainties as a prerequisite to be used for future airborne moisture budget closure in arctic ARs.
Dimensionless argument: a narrow grain size range near 2 mm plays a special role in river sediment transport and morphodynamics
Authors: Parker Gary , An Chenge , Lamb Michael P. , Garcia Marcelo H. , Dingle Elizabeth H. , Venditti Jeremy G.
Published: August 2023

Abstract. The grain size 2 mm is the conventional border between sand and gravel. This size is used extensively, and generally without much physical justification, to discriminate between such features as sedimentary deposit type (clast-supported versus matrix-supported), river type (gravel-bed versus sand-bed) and sediment transport relation (gravel versus sand). Here we inquire as to whether this 2 mm boundary is simply a social construct upon which the research community has decided to agree via repetition, convergence and rearticulation, or whether there is some underlying physics. We use dimensionless arguments to show the following for typical conditions on Earth, i.e., natural clasts (e.g. granitic or limestone) in 20 °C water. As grain size ranges from 1 to 5 mm (a narrow band including 2 mm), sediment suspension becomes vanishingly small at normal flood conditions in alluvial rivers. We refer to this range as pea gravel. We further show that bedload movement of a clast in the pea gravel range, e.g. with a size of 4 mm moving over a bed of 0.4 mm particles has an enhanced relative mobility as compared to a clast with a size of 40 mm moving over a bed of the same 4 mm particles. With this in mind, we use 2 mm here as shorthand for the narrow pea gravel range of 1 – 5 mm, over which transport behaviour is distinct from both coarser and finer material. The use of viscosity allows delineation of a generalized dimensionless bed grain size discriminator between “sand-like” and “gravel-like” rivers that is applicable to sediment transport on Titan (ice clasts in flowing methane/ethane liquid at reduced gravity) and Mars (mafic clasts in flowing water at reduced gravity) as well as Earth.
Exploring Multi-decadal Time Series of Temperature Extremes in Australian Coastal Waters
Authors: Hemming Michael , Roughan Moninya , Schaeffer Amandine
Published: August 2023

Abstract. The intensity and frequency of extreme ocean temperature events, such as Marine Heatwaves (MHWs) and Marine cold-spells (MCSs), are expected to change as our oceans warm. Little is known about marine extremes in Australian coastal waters, particularly below the surface. Here we introduce a multi-decadal observational record of extreme ocean temperature events starting in the 1940s/50s between the surface and the bottom (50–100 m) at 4 coastal sites around Australia; the Australian Multi-decadal Ocean Time Series EXTreme (AMDOT-EXT) data product. The data products include indices indicating the timing of extreme warm and cold temperature events, their intensity, and the corresponding temperature time series and climatology thresholds. We include MHWs, MCSs and shorter duration heat spikes and cold spikes. For MHWs and MCSs, which are defined as anomalies above the seasonally-varying 90th percentile lasting more than 5 days, we also provide further event information, such as their category, and onset and decline rates. Using these multi-decadal data products we show the most intense and longest extreme temperature events at these sites, which have occurred below the surface. These data records highlight the value of long-term full water column ocean data for the identification of extreme temperature events below the surface.
Stream laws in analog tectonic-landscape models
Authors: Reitano Riccardo , Clementucci Romano , Conrad Ethan M. , Corbi Fabio , Lanari Riccardo , Faccenna Claudio , Bazzucchi Chiara
Published: August 2023

Abstract. The interplay between tectonics and surface processes defines the evolution of mountain belts. However, correlating these processes through the evolution of natural orogens represents a scientific challenge. Analog models can be used for analyzing and interpreting the effect of such interaction. To fulfill this purpose it is necessary to understand how the imposed boundary conditions affect analog models' evolution in time and space. We use nine analog models characterized by different combinations of imposed regional slope and rainfall rates to investigate how surface processes respond to the presence of tectonically built topography (imposed slope) under different climatic conditions (rainfall rate). We show how the combination of these parameters controls the development of drainage networks and erosional processes. We quantify the morphological differences between experimental landscapes in terms of a proposed Se/R ratio, accounting for both observables and boundary conditions. We find few differences between analog models and natural prototypes in terms of parametrization of the detachment-limited stream power law. We observe a threshold in the development of channelization, modulated by a tradeoff between applied boundary conditions.
Throughfall spatial patterns translate into spatial patterns of soil moisture dynamics – empirical evidence
Authors: Fischer-Bedtke Christine , Metzger Johanna Clara , Demir Gökben , Wutzler Thomas , Hildebrandt Anke
Published: August 2023

Abstract. Throughfall heterogeneity induced by the redistribution
of precipitation in vegetation canopies has repeatedly been hypothesized to
affect the variation in the soil water content and runoff behavior, especially
in forests. However, observational studies relating the spatial variation in the
soil water content directly to net precipitation are rare, and few confirm
modeling hypotheses. Here, we investigate whether throughfall patterns
affect the spatial heterogeneity in the soil water response in the main rooting
zone. We assessed rainfall, throughfall and soil water content (at two depths,
7.5 and 27.5 cm) on a 1 ha temperate mixed-beech forest plot in Germany
during the 2015 and 2016 growing seasons using independent, high-resolution,
stratified, random designs. Because the throughfall and soil water content cannot
be measured at the same location, we used kriging to derive the throughfall
values at the locations where the soil water content was measured. We first
explored the spatial variation and temporal stability of throughfall and soil
water patterns and subsequently evaluated the effects of input (throughfall), soil
properties (field capacity and macroporosity), and vegetation parameters
(canopy cover and distance to the next tree) on the soil water content and
dynamics. Throughfall spatial patterns were related to canopy density. Although
spatial autocorrelation decreased with increasing event sizes, temporally
stable throughfall patterns emerged, leading to reoccurring higher- and lower-input locations across precipitation events. Linear mixed-effects model
analysis showed that soil water content patterns were poorly related to
spatial patterns of throughfall and that they were more influenced by unidentified,
but time constant, factors. Instead of the soil water content itself, the patterns of its increase after
rainfall corresponded more closely to throughfall patterns: more
water was stored in the soil in areas where throughfall was elevated. Furthermore, soil moisture patterns themselves affected the local soil water response, probably by mediating fast drainage and runoff. Locations with a low
topsoil water content tended to store less of the input water, indicating
preferential flow. In contrast, locations with a high water content
stored less water in the subsoil. Moreover, the distance to the next tree and macroporosity
modified how much water was retained in soil storage. Overall, throughfall
patterns imprinted less on the soil water content and more on the soil water
dynamics shortly after rainfall events; therefore, percolation rather than the
soil water content may depend on the small-scale spatial heterogeneity in canopy
input patterns.