bluuebunny/crossref_metadata_2025 huggingface dataset:
Praktická implementace virtuálních návodek
Authors: Kubr Jan , Novikov Konstantin , Hořejší Petr , Kleinová Jana
Published: November 2020

Pozitivní dopady využití virtuální reality v průmyslu byly již mnohokrát prokázány. Jak je to ale s reálným nasazením této moderní technologie v praxi? Tento článek se zabývá implementací virtuálních návodek na pracoviště ve velkosériové výrobě z oblasti automotive. Cílem je ukázat, že virtuální návodky jsou smysluplným nástrojem pro zaškolování pracovníků. Přesto je třeba myslet na specifika dané výroby a koncových uživatelů tak, aby došlo ke správnému nastavení systému podávání informací a bylo dosaženo požadovaného zefektivnění výroby.
The third sector and the new development paradigms
Authors: Filip Valentin
Published: November 2020

NGOs, as economic actors, are now passing a stage that could change their role in development for the long term. Developing NGOs are not only making peace with the market but are using its mechanisms to better tackle challenges such as poverty, inequality, democratic participation and bottom-up empowerment. Development projects are more sensible to the market needs and evolution while economic sustainability of their results is now a prerequisite. Furthermore, efficiency and accountability are criteria that appear in the majority of funding entities calls for projects, all of this putting a pressure on NGOs for changing their practices, their staff competences and their strategies. This evolution, perceived from the perspective of development economics theories, is contributing the confirmation of the “market solutions” approach, given by the neoliberal theories. However it is important to say that NGOs are making a selection of some large areas that can become a “refined” neoliberalism.
Apropiación territorial e informalidad urbana. Un caso en el Partido de La Plata, Buenos Aires, Argentina
Authors: Rodriguez Tarducci Rocio , Cortizo Daniela , Frediani Julieta Constanza
Published: November 2020

El presente artículo propone el análisis de la apropiación territorial en el barrio Puente de Fierro, una urbanización informal en la periferia urbana del Partido de La Plata, Buenos Aires, Argentina. La investigación se desarrolla metodológicamente a partir del trabajo de campo y la participación activa y colaborativa con los actores sociales al interior del caso de estudio. La experiencia en al barrio y con los actores contribuyó a la comprensión del valor simbólico que se le otorga a un territorio con características de lugar. De esta investigación surge que los habitantes del caso de estudio se apropian del territorio al nombrar su barrio, recorrerlo, usarlo y representarlo tanto simbólica como materialmente. El análisis permite conocer los lugares en donde se establecen las relaciones sociales y se fortalece el vínculo con el territorio, es decir, mediante la territorialización del significado delas representaciones sociales de los actores.
Berger, J. y Mohr, J. (2018). Un séptimo hombre. Imágenes y palabras sobre la experiencia de los trabajadores emigrantes en Europa
Authors: Margueliche Juan Cruz
Published: November 2020

Reseña de Berger, J. y Mohr, J. (2018). Un séptimo hombre. Imágenes y palabras sobre la experiencia de los trabajadores emigrantes en Europa
Fotoperiodismo: entre la historia y lo inmediato
Authors: Berenguer Carola
Published: November 2020

En la presente entrevista Ramiro Gómez, fotógrafo y fotoperiodista, comparte los procesos que conlleva su trabajo para Télam, Agencia Nacional de Noticias de la Argentina, tanto las decisiones técnicas y estéticas como de edición y de publicación. A su vez, reflexiona sobre la circulación de las imágenes en los medios masivos de comunicación, las redes sociales y el papel autoral dentro de la práctica fotográfica. Además, aborda las nociones de inmediatez y de calidad de las imágenes y su producción durante la cuarentena en la Argentina.
Performance in public management. A research agenda with bibliometric approach
Authors: CICEA Claudiu
Published: November 2020

In the current context of increasingly limited resources and of constantly multiplying and diversifying needs, the issue of performance (in any form of its manifestation) is becoming increasingly important. This desideratum is even more important in the field of public management, because this sector is a large consumer of resources, of any nature (material, financial, human and informational). The main objective of this paper is to perform a bibliometric analysis in the field of performance within the public management, based on the analysis of scientific production, in order to discover significant aspects and trends. The present research analyzes 3309 documents (articles) from the Web of Science database, using two specific analysis software (VOSViewer and CiteSpace). The conducted research identified three clusters, based on the analysis of titles, abstracts and keywords, which take into account the economic aspects of the analyzed field, concrete ways of evaluating performance in the field of public management and particularities of the public sector in general. Finally, the present paper analyzes which are the main papers in the field (based on citation burst), highlighting the trends in this scientific field in the last 20 years. The novelty of this paper is the bibliometric analysis (combined with a "text mining" approach), being the first of its kind in the field of performance for public management.
Solar Photovoltaic Assistance System Study for a Brazilian Light Rail Vehicle
Authors: De Almeida Carneiro Mariko , Da Fonseca Soares Diogo
Published: November 2020

Recently, much research is being developed to improve sustainability in the transportation sector due to its impact on carbon dioxide (CO2) production, climate change, and fossil fuel resources. Railways in the world have started to use solar power assistance to improve sustainability in the transportation sector. The Brazilian Company of Urban Trains operates a Brazilian Light Rail Vehicle (BLRV) for passenger transportation in Brazil. This article is a study on the potential of environmental and economic benefits of the installation of solar panels in the BLRV roof, operated in the urban metropolitan area of João Pessoa, to provide assistance on electric load. The results show that the installation of photovoltaic system in the roofs of the total fleet of BLRVs operated in João Pessoa railway can save about R$ 800,000.00 and reduce the emission of 540 tons of CO2 in 10 years.
Effect of Dietary Inclusion of Citric Acid with Phytase as Supplement on Growth Responses of Rainbow Trout
Authors: Singh Suraj Kumar , Bhandari Mahendra Prasad , Timalsina Prem
Published: November 2020

Rainbow trout, a salmonid species has an economic importance worldwide and contributes to the indigenous food security. The present study was conducted in complete randomized design (CRD) to evaluate the dietary inclusion of citric acid with phytase as supplement on growth responses of rainbow trout. There were four treatments of diets with 0.5% citric acid (T1), 1% citric acid (T2), 1.5% citric acid (T3) and 0% control (T4) of citric acid incorporated with 1200FYT phytase as supplement. The treatments were replicated three times. Total harvest weight of fish in T3 (5720.2±105.6g) was significantly higher and different than T2 (4595.9±434.9g), T1 (4589.8±240.2g) and T4 (4567.5±217.3g). The highest daily growth rate was seen in treatment T3 (1.1±0.0) which was significantly different than T2 (0.9±0.0), T1 (0.9±0.0) and T4 (0.8±0.0). The highest specific growth rate was seen in the treatment T3 (0.8±0.01) which was significantly different than T1 (0.7±0.0), T2 (0.7±0.1) and T4 (0.7±0.0). The lowest food conversion ratio was seen in T3 (2.2±0.1) which was significantly different with T2 (2.6±0.1), T1 (2.7±0.1) and T4 (2.8±0.1). Similarly, the highest protein efficiency ratio was seen in treatment T3 (1.0±0.1) which was not significantly different with T2 (0.8±0.0) and T1 (0.8±0.1) but was significantly different than T4 (0.7±0.0). No significant changes were observed in water temperature, dissolve oxygen and pH under different treatments. The present findings demonstrated that dietary inclusion of citric acid with phytase as supplement enhance growth by reducing the pH in the gut which increases the phytate hydrolysis, kills the pathogens, decreases the rate of gastric emptying, improves mineralization and nutrient absorption.
The Impact of Minimum Wages in the Environment and Culture Sector of the Expanded Public Works Programme
Authors: Baur Peter
Published: November 2020

The Public Works Programme initiated during the Great Depression in the United States was known for its ability to stimulate economic activity through employment creation. Its aim of alleviating poverty and reducing inequality finds an echo in one of the primary objectives of South Africa’s Expanded Public Works Programme (EPWP). This programme focuses on reducing unemployment through work-based programmes, in that way providing income relief to many households through job creation. The very high levels of unemployment and the associated poverty and inequality are considered to be among some of the most daunting challenges that the South African economy faces. The environment and culture sector has experienced many challenges relating to wage determination and wage-setting behaviour. The aim of this article is to investigate the impact of setting minimum wages in the environment and culture sector as an appropriate wage strategy intervention policy under the EPWP. The EPWP is a nationwide programme comprising projects that are aimed at job development. After analysing data from over 3,500 individual projects, the author found that there was a negative relationship between wage-setting behaviour and job creation as far as many individuals were concerned, especially women and youths. The author established that investment in skills development and training had a positive impact on outcomes in the Environment and Culture Sector of the EPWP.
Perfil epidemiológico da sífilis congênita em gestantes no município de Maceió
Authors: Barbosa Douglas Ferreira Rocha , Albuquerque Aline Cynara Coelho , Verçosa Rosa Caroline Mata , Dos Reis Rosane Pereira , Gonçalves Ediane , Jacob Layanne Ramalho , De Santana Kleytonn Giann Silva , Dos Santos Sidlayne , Pereira Thalita da Silva , Da Silva Margarete Batista
Published: November 2020

Objetivo: Analisar o perfil epidemiológico da sífilis congênita em gestantes no município de Maceió/AL. Métodos: Trata-se de um estudo epidemiológico caracterizado como descritivo, observacional, retrospectivo e transversal, sendo realizado a partir de dados coletados do Sistema de Informações de Agravos de Notificações de dados de sífilis congênita em gestantes no período de 2014-2019. Resultado e discussão: Embora a sífilis seja uma doença com altos índices de infecção entre as gestantes, poucas possuem informações sobre a doença, seu modo de transmissão, características, diagnóstico e tratamento. Os resultados evidenciados nesse estudo revelam que o perfil da sífilis congênita e materna no município de Maceió encontra-se com número de casos ainda alto. Conclusão: Os achados desse estudo permitem concluir que o perfil epidemiológico da sífilis congênita em gestantes no município de Maceió ainda encontra-se com um elevado número de casos com 115 casos no ano de 2019, diante disso se faz necessário à busca ativa de gestantes para realização do pré-natal, e reforçar os exames clínicos entre as que já o realizam.
Advances in the Synthesis of Fluorinated Scaffolds by Transition Metal-Catalyzed C–H Bond Activation
Authors: Mazeh Sara , Lapuh Maria Ivana , Besset Tatiana
Published: November 2020

Thanks to the unique features of the fluorine atom and the fluorinated groups, fluorine-containing molecules are essential. Therefore, the search for new fluorinated groups as well as straightforward and original methodologies for their installation is of prime importance. Especially,
the combination of organofluorine chemistry with transition metal-catalyzed C–H bond functionalization reactions offered straightforward tools to access original fluorinated scaffolds. In this context, over the last years, our group focused on the development of original methodologies
to synthesize fluorine-containing molecules with a special attention to emergent fluorinated groups. The present account highlights our recent contributions to the synthesis of highly value-added fluorine-containing compounds by transition metal-catalyzed C–H bond activation.
Implementation of Biocatalysis in Continuous Flow for the Synthesis of Small Cyclic Amines
Authors: Hegarty Eimear , Paradisi Francesca
Published: November 2020

Significant progress has been made in establishing transaminases as robust biocatalysts for the green and scalable synthesis of a diverse range of chiral amines. However, very few examples on the amination of small cyclic ketones have been reported. Cyclic ketones are particularly challenging
for transaminase enzymes because they do not display the well-defined small and large substituent areas that are characteristic for the bio- catalytic mechanism. In this work, we exploited the broad substrate scope of the (S)-selective transaminase from Halomonas elongata (HeWT)
to develop an efficient biocatalytic system in continuous flow to generate a range of small cyclic amines which feature very often in pharmaceuticals and agrochemicals. [3] Tetrahydrofuran-3-one and other challenging prochiral ketones were rapidly (5–45 min) transformed to their corresponding
amines with excellent molar conversion (94–99%) and moderate to excellent ee.
Intramolecular C(sp3)–H Bond Amination Strategies for the Synthesis of Saturated N-containing Heterocycles
Authors: Zhang Jiayu , Pérez-Temprano Mónica H.
Published: November 2020

The selective functionalization of C(sp3)–H bonds via intramolecular amination reactions represents a very attractive strategy for the construction of saturated N-containing heterocycles (SNHets). Over the past de- cades, the chemical community has devoted its
efforts towards expanding the synthetic toolbox with the aim of facilitating access to these key fragments in a controllable, reproducible and efficient manner. This review covers selected examples of the most recent advances in intramolecular C(sp3)–N bond-forming reactions
by three main approaches: (1) the Hofmann-Löffler-Freytag (HLF) reaction; (2) transition-metal-catalyzed nitrene C(sp3)–H inser- tion; and (3) transition-metal-catalyzed ligand-assisted C(sp3)–N bond-forming reactions via a reductive elimination step.
We will discuss reactivity, selectivity and the major mechanistic insights into these transformations.
A Brief History and Practical Applications in DNA Extraction
Authors: Gahlon Hailey L.
Published: November 2020

In the late 1860s, DNA was first identified by the Swiss physician and biochemist Friedrich Miescher. Since this time, we have solved its structure, learned how DNA divides in our cells, and elucidated molecular mechanisms for the transmission of our hereditary information. Fundamental
to all these discoveries is the ability to extract our DNA in high purity. In laboratories today, DNA extraction is a routine practice performed from readily available commercial kits. However, in the late 1800s, DNA extraction was an emerging method that required tedious laboratory approaches.
Mitochondria-Targeted Inhibitors of the Human SIRT3 Lysine Deacetylase
Authors: Troelsen Kathrin Sten , Bæk, Michael , Nielsen Alexander Lund , Madasen Andreas Stahl , Rajabi Nima , Olsen Christian Adam
Published: November 2020

Sirtuin 3 (SIRT3) is the major protein lysine deacetylase in the mitochondria. This hydrolase regulates a wide range of metabolically involved enzymes and has been considered as a potential drug target in certain cancers. Investigation of pharmacological intervention has been challenging due to a lack of potent and selective inhibitors of SIRT3. Here, we developed a strategy for selective inhibition of SIRT3 in cells, over its structurally similar isozymes that localize primarily to nucleus (SIRT1) and cytoplasm (SIRT2). This was achieved by directing the inhibitors straight to the mitochondria through incorporation of sequences inspired by previously described mitochondria-targeting peptides. Our inhibitors exhibited excellent mitochondrial localization in HeLa cells as indicated by fluorophore-conjugated versions and target engagement was demonstrated by a thermal shift assay of SIRT3 using western blotting. The acetylation state of documented SIRT3 target MnSOD was shown to be perturbed in cells with little effect on known targets of SIRT1 and SIRT2, showing that our lead compound exhibits selectivity for SIRT3 in cells. We expect that the developed inhibitor will now enable a more detailed investigation of SIRT3 as a potential drug target and help shed further light on the diverse biology regulated by this enzyme.
Molecular Recognition of SARS-CoV-2 Spike Glycoprotein: Quantum Chemical Hot Spot and Epitope Analyses
Authors: Watanabe Chiduru , Okiyama Yoshio , Tanaka Shigenori , Fukuzawa Kaori , Honma Teruki
Published: November 2020

Due to the COVID-19 pandemic, researchers have attempted to identify complex structures of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein (S-protein) with angiotensin-converting enzyme 2 (ACE2) or a blocking antibody. However, the molecular recognition mechanism - critical information for drug and antibody design - has not been fully clarified at the amino acid residue level. Elucidating such a microscopic mechanism in detail requires a more accurate molecular interpretation that includes quantum mechanics to quantitatively evaluate hydrogen bonds, XH/π interactions (X = N, O, and C), and salt bridges. In this study, we applied the fragment molecular orbital (FMO) method to characterize the SARS-CoV-2 S-protein binding interactions with not only ACE2 but also the B38 Fab antibody involved in ACE2-inhibitory binding. By analyzing FMO-based interaction energies along a wide range of binding inter-faces carefully, we identified amino acid residues critical for molecular recognition between S-protein and ACE2 or B38 Fab antibody. Importantly, hydrophobic residues that attribute to weak interactions such as CH-O and XH/π interactions, as well as polar residues that construct conspicuous hydrogen bonds, play important roles in molecular recognition and binding ability. Moreover, through these FMO-based analyses, we also clarified novel hot spots and epitopes that had been overlooked in previous studies by structural and molecular mechanical approaches. Altogether, these hot spots/epitopes identified between S-protein and ACE2/B38 Fab antibody may provide useful information for future anti-body design and small or medium drug design against the SARS-CoV-2.
Graphene Reinforced Polyether Ether Ketone Nanocomposites for Bone Repair Applications
Authors: Jiang Nan , Tan Peijie , He Miaomiao , Sun dan , Zhang Li , Zhu Songsong
Published: November 2020

To improve the performance of polyether ether ketone matrix (PEEK) in hard tissue repair and replacement applications, we fabricated graphene (G) reinforced PEEK with graded G concentrations (0.1%-5%) through injection molding. The mechanical properties, surface morphology, chemical composition and thermal stability of the composites have been characterized through universal mechanical testing, scanning electron microscopy, contact-angle measurement, transmission electron microscope, X-ray photoelectron spectroscopy, X-ray diffraction and thermal analysis system. The biocompatibility has been assessed in vitro and the bone repair function of the composite implant have been assessed in vivo using a rabbit mandibular bone defect model. Mechanical testing results suggest that the composite samples have compressive moduli similar to that of the natural bone. Although addition of G into PEEK does not significantly influence the composite tensile, flexural or compressive moduli, it can significantly enhance the ductility and toughness of the material. On the other hand, all G-reinforced PEEK implants demonstrated enhanced adhesion and differentiation of rat bone marrow stromal cells (BMSCs), with 5% G-PEEK showing the highest bioactivity among all samples. The in vivo osseointegration data further revealed that 5% G-PEEK has the best effect in promoting osseointegration and bone regeneration, in both early stage and late stage bone re-growth. Study shows that our G-reinforced PEEK-based implants provides a promising strategy for enhancing the performance of future regenerative bone implants.
Carbon-Loaded Flexible Electrode Films for Li-O2 Cells: Preparation, Porosity, Homogeneity and Electrochemical Characterization
Authors: gaya caroline , Franco Alejandro A. , Surcin Christine , Courty Matthieu , LARCHER Dominique
Published: November 2020

Porous (up to 70 vol. %) self-standing flexible carbon/polymer (Ketjen Black / PVdF-HFP) film electrodes are produced by leaching out a plasticizer-porogen agent (DBP = DiButyl Phtalate) from precursor films (80% ³ DBP w% ³ 40%). Textural analysis reveals that i) these films exhibit copious initial macroporosity, ii) extra open macro- and then meso-porosity are created along the leaching, iii) this leaching process impacts the internal films texture resulting in a partial closing of the pre-existing porosity, iv) only films with the lowest initial DBP contents (≤ 60 w%) are homogeneous in composition/porosity/texture. In Li/O2 cells, the first discharge capacities of these films are compared to those calculated assuming a total filling of this porosity by electrochemically formed solid Li2O2 (2700 mAh.cm-3 of pores). Up to 80 % of the maximum capacity can be reached (i.e. 80 % of the porosity filled by Li2O2), confirming the positive attributes of mixed interconnected macro/meso porosity. This is further emphasized by the very low capacities obtained with electrodes having similar porosity vol. % but totally different internal texture (GDL). These conclusions can be made despite a large discrepancy in the data, even for homogeneous films, due to reproducibility issues intrinsic to the system.
Concise asymmetric syntheses of streptazone A and abikoviromycin
Authors: Wørmer Gustav J. , Villadsen Nikolaj L. , Nørby Peter , Poulsen Thomas
Published: November 2020

Streptazone A and abikoviromycin are related alkaloids that both feature an unusual arrangement of reactive functionalities within an underlying compact tricyclic ring system. Here, we report a highly concise asymmetric synthesis of both natural products. The developed route first constructs another member of the streptazones, streptazone B1, using a rhodium-catalyzed distal selective allene-ynamide Pauson-Khand reaction as the key transformation. A regio- and enantioselective epoxidation under chiral phase-transfer catalytic conditions was then achieved to directly make streptazone A in 8 steps overall. A chemoselective, iridium-catalyzed reduction of the enaminone-system was employed to make abikoviromycin in one additional step. Studies of the intrinsic reactivity of streptazone A towards the cysteine mimic, N-acetylcysteamine, revealed unanticipated transformations, resulting in thiol conjugation to both the hindered tertiary carbon of the double allylic epoxide and in bis-thiol conjugation which may proceed via formation of a cyclopentadienone intermediate. With flexible access to these compounds, studies aimed to identify their direct biological targets are now possible.
FID-Net: A Versatile Deep Neural Network Architecture for NMR Spectral Reconstruction and Virtual Decoupling
Authors: Karunanithy Gogulan , Hansen Flemming
Published: November 2020

In recent years, the transformative potential of deep neural networks (DNNs) for analysing and interpreting NMR data has clearly been recognised. However, most applications of DNNs in NMR to date either struggle to outperform existing methodologies or are limited in scope to a narrow range of data that closely resemble the data that the network was trained on. These limitations have prevented a widescale uptake of DNNs in NMR. Addressing this, we introduce FID-Net, a deep neural network architecture inspired by WaveNet, for performing analyses on time domain NMR data. We first demonstrate the effectiveness of this architecture in reconstructing non-uniformly sampled (NUS) biomolecular NMR spectra. It is shown that a single network is able to reconstruct a diverse range of 2D NUS spectra that have been obtained with arbitrary sampling schedules, with a range of sweep widths, and a variety of other acquisition parameters. The performance of the trained FID-Net in this case exceeds or matches existing methods currently used for the reconstruction of NUS NMR spectra. Secondly, we present a network based on the FID-Net architecture that can efficiently virtually decouple 13Cα-13Cβ couplings in HNCA protein NMR spectra in a single shot analysis, while at the same time leaving glycine residues unmodulated. The ability for these DNNs to work effectively in a wide range of scenarios, without retraining, paves the way for their widespread usage in analysing NMR data.
Imagens pobres e a ostentação do pixel – Relações entre cinema e internet em Videofilia (e outras síndromes virais)
Authors: Akemi Ishii Regiane
Published: November 2020

Este artigo é dedicado à análise fílmica de Videofilia (e outras síndromes virais) (2015), de Juan Daniel F. Molero, e sua relação narrativa e estética com a internet, destacando a presença de glitches e datamoshing, técnicas que ampliam a visibilidade dos píxeis. Relacionaremos tal uso com o conceito de imagens pobres, termo cunhado por Hito Steyerl em que a autora apresenta a ambivalência das imagens que perdem resolução para ganhar velocidade e difusão. Também serão mobilizadas reflexões recentes da teoria do cinema por meio de autores como D.N. Rodowick, Francesco Casetti e Thomas Elsaesser. Assim, será possível investigar alguns modos pelos quais o cinema tem confrontado, atuado e respondido ao status das imagens contemporâneas, em que produção e circulação se tornam indistinguíveis.
Inmunoterapia en hemopatías malignas
Authors: López García Nancy del Carmen , Vivar Morán Carolina Stefania , Bravo Amores Andres Clemente , Rodriguez Avilés Diego Armando
Published: November 2020

El campo de la inmunoterapia en el tratamiento del cáncer se ha acelerado en los últimos años y ha entrado en primer plano como un área líder de investigaciones en curso y terapias prometedoras cambiando el panorama del tratamiento para una variedad de tipos de cáncer. Anteriormente, la inmunoterapia en el tratamiento de neoplasias malignas hematológicas. Sin embargo, hoy en día, este tipo de terapias biológicas es utilizada para estimular las defensas naturales del cuerpo en aras de combatir el cáncer a través de sustancias que produce el mismo cuerpo o que se procesan en laboratorios para mejorar o restaurar el sistema inmunológico del paciente, actuando en el retraso del crecimiento de las células cancerígenas, impidiendo la diseminación hacia otros órganos y ayudando al sistema inmunitario a la hora de destruir las células malignas. En el siguiente proceso investigativo se enmarca una revisión de varias formas de terapias basadas en el sistema inmunológico, que han demostrado ser muy prometedoras en pacientes con neoplasias hematológicas, incluidas las terapias monoclonales convencionales como rituximab; anticuerpos monoclonales diseñados mediante ingeniería denominados engagers de células T biespecíficas; anticuerpos monoclonales y fármacos que bloquean las vías inhibidoras de las células T (es decir, PD-1, CTLA-4 e IDO); terapia de transferencia celular adoptiva con células T diseñadas para expresar receptores de antígenos quiméricos o receptores de células T. También se evalúa la idea de usar estas terapias en combinación sugiriendo enfoques de múltiples puntas para mejorar los resultados del tratamiento y las respuestas curativas en los pacientes.
Manifestaciones cutáneas de las enfermedades de transmisión sexual (ITS)
Authors: Castro Caicedo Katherine Yelise , Mora Vélez Tatiana Lilibeth , Gavilanes Davila Fatima Liliana , Monar Luna Karina Anabel
Published: November 2020

Históricamente las Enfermedades de Transmisión Sexual (ETS), también conocidas como enfermedades venéreas o infecciones de transmisión sexual (ITS), han sido un problema importante de salud a nivel mundial. Las enfermedades de transmisión sexual (ETS), por lo general, son adquiridas por medio del contacto sexual. Cada día, más de un millón de personas contraen una infección de transmisión sexual (ITS). De tal manera que, conocer y detectar las manifestaciones cutáneas de las ETS puede ser una gran ventaja para orientar un diagnóstico temprano y, por ende, su tratamiento adecuado. Asimismo, además de controlar la enfermedad, se evita su propagación. General este tipo de material bibliográfico, que identifiquen estas lesiones es fundamental tanto para pacientes como para el profesional de la salud, ya que permite la orientación de la presencia de alguna ETS. El objetivo del presente estudio es compendiar las manifestaciones cutáneas más importantes en Sífilis, Virus de Papiloma Humano (VPH) y Virus de la Inmunodeficiencia Humana (VIH). El modelo de investigación es una revisión de tipo documental bibliográfico. Se encontró que entre las manifestaciones cutáneas más resaltantes de la sífilis se encuentra el chancro, asimismo, la sífilis secundaria anular. El VPH se caracteriza por la manifestación de diferentes subtipos de verrugas, se puede presentar la enfermedad de Bowen y la epidermodisplasia verruciforme. En el caso del VIH son frecuentes el sarcoma de Kaposi, herpes simple, leishmaniasis atípicamente diseminado, penicilosis diseminada, dermatitis seborreica, herpes Zoster, psoriasis severa, linfoma cutáneo, entre otros. Por último, es importante conocer las diferentes manifestaciones de las ETS por cuanto permiten la orientación de un diagnóstico precoz en algunos casos, establecer el manejo adecuado y evitan la propagación de la enfermedad.
Sequência didática para o ensino de Anatomia Humana: proposta com metodologia ativa associada ao uso do smartphone
Authors: Manhães Marcelle de Oliveira , Batista Silvia Cristina Freitas , Marcelino Valéria de Souza
Published: November 2020

No Ensino de Ciências, cada vez mais se têm discutido a importância de repensar a prática educacional, buscando alternativas que colaborem para o processo de ensino e aprendizagem. O uso de aplicativos em smartphones é uma estratégia que pode trazer contribuições em aulas de Anatomia Humana ao, por exemplo, favorecer visualizações e a realização de atividades diferenciadas. Porém, a utilização desses recursos deve estar associada a uma proposta metodológica adequada. Neste trabalho, considera-se a metodologia dos Três Momentos Pedagógicos (3MP), que visa criar situações para desenvolver a capacidade investigativa e o raciocínio para a resolução de problemas. Nesse contexto, este artigo tem como objetivo apresentar a análise das contribuições pedagógicas de uma Sequência Didática (SD), baseada na metodologia dos 3MP e apoiada no uso de smartphones, para o estudo dos sistemas respiratório, circulatório e endócrino, em aulas de Biologia, no Ensino Médio. A pesquisa teve caráter qualitativo, a partir de uma intervenção pedagógica realizada com alunos da 2ª série do Ensino Médio de um Colégio Estadual do Rio de Janeiro. Os dados coletados sinalizaram que, em geral, a SD contribuiu para despertar a curiosidade e estimular a participação dos alunos, resultando no aprimoramento das concepções acerca dos conceitos científicos estudados.
Quando os números falam: a evasão da licenciatura em Matemática EaD da Unicesumar de 2014 a 2018
Authors: Ramos Antoneli da Silva , Gomes Paulo Cesar
Published: November 2020

Nosso objetivo neste artigo foi investigar a evasão escolar no Curso de Licenciatura em Matemática EaD da UniCesumar em polos de diferentes cidades e estados brasileiros na percepção dos evadidos. A Evasão Escolar no Ensino Superior, particularmente nos cursos de formação de professores, é um fenômeno multideterminado com graves consequências à Educação. O curso de Licenciatura em Matemática não se revela exceção em relação a isto: o que motiva estudantes a abandonarem a graduação? O Censo 2017 revelou que, daqueles licenciandos que permanecem no curso, uma ínfima parcela de 8% a 10% conseguem o diploma. Nesta pesquisa qualitativa, realizamos entrevistas semiestruturadas pelo Skype App com estudantes evadidos e estes revelaram motivações como: desemprego, problemas de saúde, gravidez, falta de contato pessoal, falta de qualidade do curso e dos materiais, mau atendimento e até mesmo a distância do polo.
Фотохимия нитрозокомплексов рутения в твердом теле и растворах и её потенциальные применения
Authors:   Институт неорганической химии им. А.В. Николаева СО РАН, Новосибирск, Россия, Михайлов А.А. , Столярова Е.Д. , Костин Г.А.
Published: November 2020

Обзор посвящен фотохимическим превращениям нитрозокомплексов рутения в различных средах и возможностям их потенциального применения. Рассмотрены реакции обратимой фотоизомеризации нитрозогруппы в метастабильные связевые изомеры в твердом теле и методы, позволяющие изучать указанные превращения, а также реакции фотолиза нитрозокомплексов в растворах.
Особенности молекулярных структур и кристаллических упаковок стирилдиазинов
Authors:   Российский химико-технологический университет им. Д.И. Менделеева, Москва, Россия, Сайфутярова А.Э. , Карноухова В.А. , Гулакова Е.Н. , Федорова О.А. , Федянин И.В. ,   Институт элементоорганических соединений им. А.Н. Несмеянова РАН, Москва, Россия,   Российский экономический университет имени Г.В. Плеханова, Москва, Россия
Published: November 2020

Исследованы кристаллические структуры трех изомерных производных стирилдиазинов (E)-2-(3,4-диметоксистирил)пиразина, (E)-2-(3,4-диметоксистирил)пиримидина и (E)-4-(3,4-диметоксистирил)пиримидина с различным положением атомов азота — потенциальных исходных соединений в качестве таких биологически активных агентов, как антибактериальные или противоопухолевые, также могут выступать в роли пестицидов и фунгицидов, красителей, аналитических реагентов. Несмотря на близость химического строения и геометрических параметров молекул в кристалле, мотивы кристаллической упаковки трех рассмотренных соединений существенно различаются. Проведенные методом PBE0/6-31G(d,p) квантово-химические расчеты показали возможность реализации нескольких конформеров молекул с близкими энергиями, в том числе наблюдаемых в кристалле; а также возможность перехода между ними с барьерами, не превышающими 43.5 кДж/моль. Наибольшая плотность при 120 K и наибольшая энергия кристаллической решетки, рассчитанная по силовому полю UNI, наблюдается для пиримидинового производного (E)-2-(3,4-диметоксистирил)пиримидина (6). Только для этой структуры из-за наличия в кристалле центросимметричных димеров с расстоянием между атомами олефиновых фрагментов порядка 3.9 Å возможна фотоциклизация в твердом состоянии.
Синтез и термические свойства двойной комплексной соли бисоксалатопалладата хлоропентаамминхрома(III)
Authors:   Институт неорганической химии им. А.В. Николаева СО РАН, Новосибирск, Россия, Лагунова В.И. , Филатов Е.Ю. , Плюснин П.Е. , Комаров В.Ю. , Мартынова С.А. , Коренев С.В. ,   Новосибирский государственный университет, Россия
Published: November 2020

Впервые синтезирована двойная комплексная соль [Cr(NH3)5Cl][Pd(C2O4)2], по порошковым данным определено, что структура соединения относится к триклинной сингонии с параметрами элементарной ячейки: a = 3.225(3) Å, b = 10.290(6) Å, c = 11.390(6) Å, α = 116.5(2)°, β = 97.9(2)°, γ = 91.2(5)°, V = 334.5 Å3 (комнатная температура). Проведены подробные исследования термических свойств в различных газовых атмосферах с привлечением методов РФА, ИК и КР спектроскопии для идентификации промежуточных и конечных продуктов термолиза. Установлена последовательность стадий термодеструкции двойной комплексной соли в инертной и восстановительной атмосферах и формирования конечного продукта термолиза — двухфазной смеси палладия и оксида хрома(III).
Строение и свойства гетеролигандного комплексного соединения стеарата гадолиния с бензоилтрифторацетоном
Authors:   Кубанский государственный университет, Краснодар, Россия, Иванин С.Н. , Бузько В.Ю. , Соколов М.Е. , Магомадова М.А. , Панюшкин В.Т. ,   Чеченский государственный университет, Грозный, Россия
Published: November 2020

Методами ИК спектроскопии и элементного анализа установлен состав синтезированного гетеролигандного комплексного соединения стеарата гадолиния с бензоилтрифторацетоном (GdSt2BTFA·2H2O). Методами оптической микроскопии и рентгенофазового анализа определено, что указанное соединение представляет собой хорошо кристализованный порошок. Получены спектры ЭПР порошка стеарата гадолиния с бензоилтрифтор­ацетоном в диапазоне 103—293 K. Определен параметр тонкой структуры D = 1329.6 МГц. Согласно с квантово-химическими расчетами, методом теории функционала плотности установлено, что наиболее вероятная точечная группа симметрии для синтезированного гетеролигандного комплекса стеарата гадолиния с бензоилтрифторацетоном — D2d. Определены температура Кюри θ = 13.52 K, константа Кюри С = 2.42 м3·K/кг, рассчитан эффективный магнитный момент μeff = 7.93 mB во всем исследуемом температурном диапазоне для порошка стеарата гадолиния с бензоилтрифторацетоном.
Кристаллическая структура [Cu(NH3)2]2[{Cu(NH3)}2{Cu(NH3)(OH)}Re6Se8(CN)6]
Authors:   Институт неорганической химии им. А.В. Николаева СО РАН, Новосибирск, Россия, Ермолаев А.В. , Смоленцев А.И. , Миронов Ю.В.
Published: November 2020

Цепочечный координационный полимер [Cu(NH3)2]2[{Cu(NH3)}2{Cu(NH3)(OH)}·Re6Se8(CN)6] (1) получен реакцией Cs2.75K1.25[Re6Se8(CN)4(OH)2]·H2O c CuCN в концентрированном водном растворе аммиака в гидротермальных условиях. Соединение кристаллизуется в гексагональной сингонии, пространственная группа P63/m, с параметрами элементарной ячейки a = 9.9902(2) Å, b = 9.9902(2) Å, c = 19.4469(7) Å, γ = 120.00°, V = 1680.85(8) Å3, Z = 2, dвыч = 4.661 г/см3. Кристаллическая структура построена из анионных полимерных цепочек [{Cu(NH3)}2{Cu(NH3)(OH)}Re6Se8(CN)6]2– и комплексных катионов [Cu(NH3)2]+, находящихся в полостях. Полученное соединение охарактеризовано методами РСА, ИК и элементного анализа.
Impact of the COVID-19 pandemic on testing services for HIV, viral hepatitis and sexually transmitted infections in the WHO European Region, March to August 2020
Authors: Simões Daniel , Stengaard Annemarie Rinder , Combs Lauren , Raben Dorthe ,   The EuroTEST COVID-19 impact assessment consortium of partners
Published: November 2020

We present preliminary results of a coronavirus disease (COVID-19) impact assessment on testing for HIV, viral hepatitis and sexually transmitted infections in the WHO European Region. We analyse 98 responses from secondary care (n = 36), community testing sites (n = 52) and national level (n = 10). Compared to pre-COVID-19, 95% of respondents report decreased testing volumes during March–May and 58% during June–August 2020. Reasons for decreases and mitigation measures were analysed.
Determination of Optimum Parameters for Anaerobic Thermophilic Bacterium Injection using Commercial Simulator: Core Flooding Validation and Sensitivity
Authors: Koto A.
Published: November 2020

The objective of this paper is to determine the optimum anaerobic-thermophilic bacterium injection (Microbial Enhanced Oil Recovery) parameters using commercial simulator from core flooding experiments. From the previous experiment in the laboratory, Petrotoga sp AR80 microbe and yeast extract has been injected into core sample. The result show that the experiment with the treated microbe flooding has produced more oil than the experiment that treated by brine flooding. Moreover, this microbe classified into anaerobic thermophilic bacterium due to its ability to live in 80 degC and without oxygen. So, to find the optimum parameter that affect this microbe, the simulation experiment has been conducted. The simulator that is used is CMG – STAR 2015.10. There are five scenarios that have been made to forecast the performance of microbial flooding. Each of this scenario focus on the injection rate and shut in periods. In terms of the result, the best scenario on this research can yield an oil recovery up to 55.7%.
INTEGRAL SOLUTIONS OF NON-HOMOGENEOUS QUINTIC EQUATION WITH FIVE UNKNOWNS 3(x^4-y^4)=26(z^2-w^2)p^3
Authors: Gopalan M.A. , Krithika V. , VijayaSankar A.
Published: November 2020

The non-homogeneous quantic equation with five unknowns represented by 3(x^4-y^4)=26(z^2-w^2)p^3  is analyzed for its non-zero distinct integral solutions. A few interesting relations among the solutions are exhibited.
Las demandas de memoria, verdad y justicia en el testimonio público de los responsables del terrorismo de Estado en Argentina
Authors: Vecchioli Virginia , Fioravanti Eduardo
Published: November 2020

Este artículo trata sobre las formas en las que un conjunto de actores vinculados al sector castrense en Argentina construye testimonios públicos que reivindican la condición de preso político de los militares que cumplen condena por su responsabilidad en la violación de los derechos humanos durante la dictadura y reclaman una memoria completa, una justicia independiente y el reconocimiento de todas las víctimas del conflictivo pasado nacional. Se analiza un corpus de 204 cartas de lectores publicadas en un diario de circulación nacional. Se identifican los recursos utilizados en la producción de estos testimonios, las propiedades sociográficas de sus autores, los temas que se tratan y los emblemas instituidos en el uso de estas cartas.
Trichoderma viride inoculated in the growing medium for the vitamin C increase in the leaves of Kalanchoe spp. and defense against Pithyum sp.
Authors: Domenico Prisa
Published: November 2020

The article presents the results of research on succulents such as Kalanchoe pinnata, Kalanchoe tubiflora and Kalanchoe gastonis-bonnieri, aimed at improving plant growth and defense against the pathogenic fungus Pythium sp., through the use of Trichoderma viride inoculated in the medium. Objectives of the work were: 1) use Trichoderma viride to assess whether the use of this endophytic fungus can increase the growth rate of Kalanchoe pinnata, Kalanchoe tubiflora and Kalanchoe gastonis-bonnieri, plants generally slow in their growth cycle; 2) evaluate if using Trichoderma viride can lead to an increase in vitamin C content in the leaves of Kalanchoe spp.; 3) assess and evaluate how the use of Trichoderma viride allows greater protection of the roots from Pithyum sp. which often affects the roots of these succulents. The two experimental groups in cultivation were: i) group without Trichoderma spp., irrigated with water and substrate previously fertilized; ii) group with Trichoderma viride, irrigated with water and substrate previously fertilized. The test showed a significant increase in agronomic parameters analyzed in plants treated with Trichoderma viride. In fact, all plants treated showed a significant increase in height and number of leaves per plant, vegetative and root weight of plants, number and weight of new shoots, total number of germinated seeds/ 100 seeds sown and a significant reduction in average germination time. In addition, plants treated with Trichoderma show an increase in leaf vitamin C content, dry mass and a reduction in plant mortality due to Pythium sp. Tricoderma can also optimize the use of fertilizers and water by facilitating the cultivation of plants in certain locations subject to biotic and abiotic stress.
KAJIAN TENTANG PENDIDIKAN KARAKTER PADA SEKOLAH RAMAH ANAK UNTUK SISWA KELAS V
Authors: Saadah Laelatus , Setiyoko Didik Tri , Mumpuni Atikah
Published: November 2020

Pendidikan karakter merupakan pendidikan yang harus diterapkan pada anak sedini mungkin untuk mencegah adanya perilaku menyimpang seperti Bullying, rumusan masalah dalam penelitian ini adalah pola pembelajaran pendidikan karakter agar anak terhindar dari kasus bullying dan faktor pendukung pola pembelajaran pendidikan karakter agar anak terhindar dari bullying pada program sekolah ramah anak. Metodologi dalam penelitian ini menggunakan metodologi penelitian kualitatif deskriptif dengan pendekatan yang di gunakan yaitu pendekatan fenomenologi. Teknik pengumpulan datanya menggunakan metode observasi, wawancara,  dan dokumentasi. Hasil penelitian ini menggambarkan bahwa pola pembelajaran pendidikan karakter agar anak terhindar dari kasus Bullying yaitu dengan cara melakukan pembiasaan positif. Faktor pendukung di SD Negeri Klampok 01 terhadap keberhasilan sekolah yaitu sikap keteladanan yang diterapkan oleh seluruh tenaga pendidik terutama kepala sekolah tentang pembiasaan yang baik dalam sekolah yang harus di dukung oleh seluruh perangkat sekolah, baik bapak/ibu guru, kepala sekolah, staf maupun penjaga sekolah. Pada penelitian ini dapat disimpulkan bahwa pola pendidikan karakter dan faktor pendukung agar anak terhindar dari kasus Bullying yaitu dengan cara pembiasaan yang positif dan keteladanan yang harus diterapkan oleh seluruh warga sekolah. Dalam hal ini peranan guru dalam mengembangkan strategi pembelajaran Pendidikan karakter harus di dukung oleh semua warga, baik warga sekolah maupun warga masyarakat.
Toplumsal Cinsiyet Eşitsizliğinin İrrasyonelliği ve Kamusal Alandaki Yansımaları
Authors: ŞEKER Aziz
Published: November 2020

Bir toplum içinde kadının sosyal durumu, o toplumun toplumsal yapısına ilişkin genel özellikleri hakkında bilgi verir. Toplumsal cinsiyet eşitsizliği kadınlar söz konusu olduğunda toplum tarihi içinde; politika, çalışma yaşamı, sanat, aile gibi alanlarda küresel bir insan hakları sorunu ve bir sosyal sorun olarak yaşanmaktadır. Bu nedenle toplumsal yapı çözümlenirken, kamusal alanın yanı sıra mahrem alanda kadınlarla ilgili eşitsizliklerden yola çıkılmaktadır. Bu anlamda kadına yönelik şiddet üzerine bir bakış açısı geliştirmeyi düşünüyorsak, toplumsal cinsiyet kavramını kendi tarihselliği ve dinamiği içinde işlemeyi önceliklerimiz arasına alırız. Çünkü kadın aleyhine olan bir toplumsal cinsiyet hiyerarşisini kabullenmek kadına ve kız çocuğuna yönelik tutumların gerekçeleri açısından bir tartışma alanı açmaktadır. Bu çalışmada toplumsal cinsiyet eşitsizliği açısından kadınlığın durumu küreselleşme, yoksulluk, medya, kadına yönelik şiddet, edebiyat vb. olgular üzerinden gidilerek değerlendirilirken, kadını dışlayan ve aşağılayan (mizojinik) koşullara ilişkin sosyolojik bir çözümleme yapılacaktır. Ayrıca toplumsal gelişme ve kadın olgusunu görmek açısından toplumsal cinsiyet eşitsizliğini besleyen koşullar kritik edilecektir.