bluuebunny/crossref_metadata_2025 huggingface dataset:
Recurrent Medulloblastoma: Complete Response and > than 21 Years and Five Months Overall Survival in a One-Year and SevenMonth-Old Male Treated with Antineoplastons
Authors:   Burzynski Clinic, Houston, Tx, USA, Burzynski Stanislaw R , Burzynski Gregory S ,   Burzynski Clinic, Houston, Tx, USA, Janicki Tomasz ,   Burzynski Clinic, Houston, Tx, USA, Beenken Samuel ,   Oncology Writings, Calera, Al, USA
Published: November 2023

Medulloblastomas arise in the posterior fossa, primarily in the region of the fourth ventricle. Recurrent medulloblastomas are high-risk and have a bad prognosis. Objectives: the case of a male child with recurrent, disseminated medulloblastoma is presented to detail the efficacy of ANP therapy (Antineoplaston A10 {Atengenal} and Antineoplaston AS2-1 {Astugenal}) in the treatment of high-risk medulloblastoma. This child was treated at the Burzynski Clinic (BC), as a Special Exception, according to Protocol BT-12, “Phase II Study of Antineoplastons A10 and AS2-1 in Children with Primitive Neuroectodermal Tumors”, with intravenous (IV) ANP therapy via a subclavian catheter and infusion pump. Tumor response was measured by sequential magnetic resonance imaging (MRI) of the brain with gadolinium enhancement. Findings: This child initially underwent tumor resection, placement of ventricular shunts, and chemotherapy, all performed elsewhere. Baseline MRI at the BC revealed recurrent, disseminated, and enhancing disease measuring 9.10 cm2 in total. IV ANP therapy began in March 2001 and ended in December 2002 after a complete response (CR) was achieved based on MRI criteria. Subsequently, the child received oral Antineoplastons as maintenance therapy, which were discontinued after eight months. At last follow-up, > 21 years and eight months since diagnosis and > 21 years and five months since the start of IV ANP therapy, the patient was well and showing no evidence of tumor recurrence. Conclusions: The utilization of ANP therapy to cure a patient with recurrent medulloblastoma is presented. We conclude that ANP therapy is an attractive therapeutic option for children with medulloblastoma
The culture of innovation. Ecuadorian Banana Companies case study
Authors: Alarcon Gamboa Ingrid Betzabe , Leon Saltos Amparito Cecilia , Lopez Paredes Maria Alexandra
Published: November 2023

The culture of innovation becomes a necessary practice in all companies. It is a key point of these, and through its application, it is intended to be updated in development and organizational competitiveness. The research aims to identify the culture of innovation in small Ecuadorian banana companies. The methodology used was quantitative-descriptive and correlational to determine the impact of innovation on the organizational culture. Initially, Cronbach's Alpha, which was 0.97, was applied, corresponding to the reliability of the questionnaire formulated based on 17 questions. Later, the Kaiser Meyer Olkin (KMO) test gave a result of 0.89, which allowed a factor analysis; finally, two reduced factors and the correlation of variables were obtained. In conclusion, it is asserted that in small Ecuadorian banana companies, the culture of innovation is not applied properly.
Perception and Uptake of HIV/AIDS Voluntary Counselling and Testing Among Women in Akinyele Local Government Area, Ibadan.
Authors: Mariam Onakoya Tolulope , Ndikom Chizoma
Published: November 2023

Introduction: At the end of 2020, there were reportedly 37.7 million HIV-positive individuals. HIV testing has been marketed as a crucial first step method to diagnose, treat, and prevent human immunodeficiency virus (HIV) infection. It is the cornerstone of all HIV prevention initiatives. The study's main aim was to ascertain the degree of HIV and HIV VCT (voluntary counselling and testing) awareness among women in Akinyele Local Government Area, Ibadan, as well as their attitudes towards HIV VCT and the rate at which they adopted the treatment. Method: This study employed a descriptive study design aimed at assessing the perception and uptake of HIV VCT among women residing in Akinyele Local Government Area, Ibadan, Oyo state. The total population of the women was 410. The sample size was determined using the Taro Yamane formula and the sample size was 220 women which was allocated proportionally to each primary health care center. The research instrument used for the study is a self-administered questionnaire.
 
Results: The results showed that more than 75% of respondents had good understanding of HIV and HIV VCT, and that 65% had positive perceptions of HIV VCT. The study found that there is no significant association between women's level of education and their level of knowledge on HIV and HIV VCT and conclude that there is no significant association between women's perception of HIV and HIV VCT and HIV VCT uptake.
 
Conclusion: In conclusion, the result revealed like other related studies that the attitude of women in Akinyele local government towards HIV Voluntary Counselling and Testing is just a little above average which means quite a number of the respondents are still not willing to take HIV VCT. Hence, the women need more sensitization on the importance and benefits of HIV VCT.
TÉCNICAS DE REPRODUÇÃO ASSISTIDA UTILIZADAS EM MULHERES ACIMA DE 50 ANOS: DESAFIOS, RISCOS E BENEFÍCIOS
Authors: Do Carmo Siqueira Nátally , Duarte Mendes Mayara , Alves Geishofer Rafaela , Rosa de Jesus Joyce de Cassia
Published: November 2023

Atualmente, mais mulheres vêm optando por uma gravidez “tardia”, devido às responsabilidades pessoais, como estudos, trabalho e outras questões. Dessa forma, a procura por técnicas de reprodução tem aumentado significativamente, o que ainda não é bem aceito em nossa sociedade, ocasionando uma batalha psicológica e até fisiológica para o casal. Durante o envelhecimento, o corpo feminino diminui sua capacidade reprodutiva, tornando, assim, mais difícil uma gravidez natural. Por isso, existem técnicas abordadas em mulheres com idade superior a 50 anos, que representam um menor risco para a mãe e para o feto. Tratando-se de uma gravidez tardia, é extremamente importante que haja o acompanhamento médico para que a saúde física e psicológica do casal seja preservada. A Fertilização In Vitro (FIV), Transferência de embrião congelado (TEC) e Injeção Intracitoplasmática de Espermatozoides (ICSI) são as três técnicas com maior taxa de sucesso, tendo como maior fator de intercorrência a idade da mulher.  Embora ainda existam riscos à saúde da mãe e do feto, com os avanços na área da reprodução assistida, é possível tornar esse sonho realidade, facilitando a vida de casais que não vivenciaram uma gravidez antes de alcançarem seus objetivos pessoais e profissionais. Nesta revisão, abordamos a taxa de sucesso de algumas técnicas de reprodução assistida em mulheres acima dos 50 anos de idade, dando ênfase àquelas com maior probabilidade de sucesso, tendo em vista que determinados procedimentos possuem uma idade máxima para sua realização.
Cultural Heritage of Bosnia and Herzegovina II: Manuscripts of the Elči Ibrahim Pasha’s Madrasa in Travnik
Authors: Mašić Madžida
Published: November 2023

This paper presents the manuscript collection of the Elči Ibrahim Pasha’s madrasa in Travnik. This collection contains 105 manuscript codices written in Arabic, Turkish and Persian. In the 1940s, the manuscript collection of this madrasa was transferred to the Gazi Husrev Bey library in Sarajevo, as part of a project that included the storage of manuscripts from all madrasas in Bosnia and Herzegovina in a suitable place. Nevertheless, even after that year, manuscripts continue to arrive in this library, so today it contains a solid manuscript collection. Although it was digitized in 2012 in the manuscript digitization project of the Bosnian manuscript collections by the Yunus Emre Institute, the catalogue of this manuscript collection has never been presented.
Pragmatic representations and online comprehension: Lessons from direct discourse and causal adjuncts
Authors: Duff John , Anand Pranav , Brasoveanu Adrian , Rysling Amanda
Published: November 2023

Studies on the reading of appositive relative clauses (ARCs) have found that ARCs seem to exhibit less influence in later parsing and decision-making than similar constructions (Dillon et al. 2014, 2017), a pattern we call discounting. Existing accounts often link discounting to the status of ARCs as independent segments in systems of pragmatic representation. This would predict discounting for other constructions as well. In this study, we test that prediction by investigating the reading of direct discourse speech reports and causal adjuncts in English. Diagnostics supplied by the theoretical literature show that these constructions contribute the same independent segments as ARCs in two different systems of pragmatic organization: direct discourse reports contribute an independent speech act, and causal adjuncts contribute their own discourse units. Nevertheless, in a series of five experiments, we find no evidence of ARC-like discounting for either. We conclude that discounting should not be linked to either of these pragmatic representations, and discuss the outlook for other approaches to the phenomenon.
Number Agreement Attraction in Czech and English Comprehension: A Direct Experimental Comparison
Authors: Chromý Jan , Brand James Liam , Laurinavichyute Anna , Lacina Radim
Published: November 2023

Number agreement attraction in comprehension is a phenomenon that has been documented in various typologically diverse languages. This evidence has led to claims about the cross-linguistic uniformity of agreement attraction effects and its independence from the grammatical features of a particular language. However, recent research has shown that in Czech, number agreement attraction effects are either absent or negligible in size. This directly contradicts the cross-linguistic uniformity hypothesis. The current paper aims to further corroborate this finding and presents a direct experimental comparison of Czech and English. Two comparable self-paced reading experiments were conducted using stimuli that were translation equivalents in Czech and English. Our analyses demonstrate a preference for the null model in Czech (no agreement attraction), unlike in English, where an interaction between verb number and attractor number was preferred. Moreover, when we compare the data from the two experiments directly, we find that the interaction between language and attraction was also preferred. In sum, we provide evidence against the cross-linguistic uniformity hypothesis for agreement attraction effects and suggest that processing patterns may differ between languages even for almost identical structures, such as agreement relations.
Adsorption of Cefixime from aqueous solutions by biochar prepared from pine leaves (Pinus kesiya)
Authors: Huynh Phuong Thao  , Nguyen Van Ha  , Nguyen Tien Dat  , Nguyen Phi Ho  , Tran Nguyen Ngoc Duyen
Published: November 2023

Nowadays, water pollution due to antibiotics is a serious matter. This present research investigated to analyze the characteristics of biochar from pine leaves (Pinus kesiya) to remove the antibiotic Cefixime from aqueous solutions. The influence of some factors: pH (2-10); contact time (10-240 mins); initial concentration of Cefixime were carried out. The characterization of materials was determined by using FT-IR (Fourier Transform Infrared Spectrometer), BET (Brunauer - Emmett - Teller), and SEM (Scanning Electron Microscope). Biosorption data was suitable for Langmuir and Freundlich isotherm models. Through the linear equation of the Langmuir isotherm model, the maximum adsorption capacities of Cefixime (qmax) were 21,51 mg/g. The biosorption process obeyed the Pseudo second-order kinetic models. This research proves that biochar is a potential biosorbent for antibiotic Cefixime removal from an aqueous solution with high efficiency, low cost, and environmental friendliness.
Synthesis of Pt-Au nanoparticles supported on reduced graphene oxide as a highly active and durability catalyst for electro-oxidation of ethanol
Authors: Nguyen Tien Hoang  , Nguyen Bich Ngoc  , Nguyen Quang Minh  , Nguyen Hong Lien  , Vu Thi Thu Ha
Published: November 2023

Design of advanced electrocatalyst, with high active and stability in electro-oxidation reactions for Direct Alcohol Fuel Cells system is urgent scientific need in the context of electrochemical energy application. Herein, Pt-Au nanoparticles supported on reduced graphene oxide, with low content of metals (With the theoretical content of 1.87% (Au) and 4.67% (Pt)), as a highly active and durability catalyst for electro-oxidation of ethanol is successfully synthesized. The current density (mass specific activity) of the PtAu/rGO catalyst for electro-oxidation ethanol, in alkaline media, was 13195 mA mgPt-1, which is 1.26 times higher than that of the Pt/rGO catalyst. After 4000s, the current density of PtAu/rGO catalyst reached 317 mA mgPt-1, is higher than that of Pt/rGO catalyst, reaching 172 mA mgPt-1. The high catalytic activity and stability of the bimetallic PtAu/rGO catalyst in the electrochemical oxidation of ethanol in alkaline medium are attributed to the synergistic effect of Au, Pt and rGO, among which, Au not only plays the role of enhancing the dispersion of Pt, but also has the effect of preventing the agglomeration of Pt nanoparticles during the reaction. This research could open up the potential to develop advanced bimetallic PtAu materials that can be used as electrochemical catalysts for various reactions.
Direct synthesis of V2O5 from metals and study the adsorption properties with organic dyes
Authors: Vu Thanh Dong  , Nguyen Thi Huong
Published: November 2023

Scientists from all around the world are currently interested in vanadium oxide (V2O5) due to its applications in fuel cells, display components, poisonous gas sensors,... The ability to absorb dyes for environmental treatment is the most remarkable among them. In this paper, the authors have presented a direct synthesis of V2O5. The sample were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), UV–visible spectrophotometry (UV-Vis) and Raman spectroscopy. The authors also investigated the adsorption properties of prepared V2O5 with Methylene Blue (MB) - a colorant widely used in the dyeing industry that causes great harm to the environment and health. The results show that the material can absorb MB up to 90% in the absence of light after 3 minutes. Finally, a few other organic dyes were investigated in order to evaluate the materials' selectivity.
The Future of the Past – Housing in Blade Runner
Authors: Nogueira Alex , Farias Hugo
Published: November 2023

Architecture, in addition to the role of setting in the film industry, can also be an element of discussion, interpretation, and generalisation. Many works have already been developed from this perspective. In this context, the dystopian universe presented in the science fiction movie Blade Runner (1982, directed by Ridley Scott) and its sequel – Blade Runner 2049 (2017, directed by Denis Villeneuve), deserve mention. The films have a time interval of 30 years in relation to the fictional chronology of the original movie and 35 years elapsed in conventional chronology. It is precisely these temporal windows that motivate us to observe and investigate the endurance, transformations, and relationships in the domestic space, starting from the representations of the internal environments of the protagonists’ apartments in both films. The goals focus on being able to observe the spatial and functional variations of dwellings between the different time frames proposed by the films in order to understand how they represent the relationship between space and technology (in a broad sense) within the domestic domain. The methodology is based mainly on comparing the protagonists’ apartments presented in each movie (case studies), observing spatiality, domestic functions, type, uses, etc. (through the development of a redraw of the floor plans of both apartments and quantitative and qualitative analyses). We chose to explore fictitious architectural narratives, “made” to house androids/replicants, to investigate the relationship between technology and domesticity in contemporary times.
Dependency of the impacts of geoengineering on the stratospheric sulfur injection strategy part 2: How changes in the hydrological cycle depend on injection rates and model?
Authors: Laakso Anton , Visioni Daniele , Niemeier Ulrike , Tilmes Simone , Kokkola Harri
Published: November 2023

Abstract. This is the second of two papers where we study the dependency of the impacts of stratospheric sulfur injections on the used model and injection strategy. Here, aerosol optical properties from simulated stratospheric aerosol injections using two aerosol models (modal scheme M7 and sectional scheme SALSA), as described in Part 1, are implemented consistently into EC-Earth, MPI-ESM and CESM Earth System Models to simulate the climate impacts of different injection rates ranging from 2 to 100 Tg(S)yr−1. Two sets of simulations were simulated with the three ESMs: 1) Regression simulations, where abrupt change in CO2 concentration or stratospheric aerosols over preindustrial conditions were applied to quantify global mean fast temperature independent climate responses and quasi-linear dependence on temperature and 2) equilibrium simulations, where radiative forcing of aerosol injections with various magnitudes compensate the corresponding radiative forcing of CO2 enhancement to study the dependence of precipitation on the injection magnitude; the latter also allow to explore the regional climatic responses. Large differences in SALSA and M7 simulated radiative forcings in Part 1 translated into large differences in the estimated surface temperature and precipitation changes in ESM simulations: e.g. an injection rate of 20 Tg(S)yr−1 in CESM using M7 simulated aerosols led to only 2.2 K global mean cooling while EC-Earth – SALSA combination produced 5.2 K change. In equilibrium simulation, where aerosol injections were used to compensate for radiative forcing of 500 ppm atmospheric CO2 concentration, global mean precipitation reduction varied between models from -0.7 to - 2.4 %. These precipitation changes can be explained by the fast precipitation response due to radiation changes caused by the stratospheric aerosols and CO2 because global mean fast precipitation response is rather negatively correlated with global mean absorbed radiation. Our study shows that estimating the impact of stratospheric aerosol injection on climate is not straightforward. This is because the capability of the sulfate layer to reflect solar radiation and absorb LW radiation is sensitive to the injection rate as well as the aerosol model used to simulate the aerosol field. These findings emphasize the necessity for precise simulation of aerosol microphysics to accurately estimate the climate impacts of stratospheric sulfur intervention. This study also reveals gaps in our understanding and uncertainties that still exist related to these controversial techniques.
Wavelength-gated control over material properties in hydrogel networks
Authors:   , Pelloth Jessica Laura
Published: November 2023

The present thesis focusses on stimuli-responsive small molecules and their utilisation in hydrogel networks to improve control over a change in physical properties. While recent literature shows a toughening of materials through different control mechanisms, there are very few examples of a stepwise softening of hydrogel networks. This thesis aims to investigate several molecular control mechanisms to introduce a stepwise change in macroscopic properties via different wavelengths of light, enabling a precise and direct control over disparate material properties and allowing for fine-tuning post preparation. Here, different approaches were utilised, ranging from reversible thermo-couplings, photo-degradation, to isomerisation of a photo-switch.
Effect of Health Coaching on the Community's Availability to Vaccinate
Authors: Najamuddin Nur Isriani , Wahab Masyita , Amin Hadryani , Amin Hadryani , Marsida Andi
Published: November 2023

Background: The number of negative issues regarding COVID-19 affects the public's perception of not participating in the COVID-19 vaccination. Based on a brief interview conducted by the researcher with 20 people in the Matangnga Health Center working area regarding the implementation of vaccination, 17 people expressed their doubts and were not willing to vaccinate. Because in this study, what needs to be changed is the public's perception of the COVID-19 vaccination, the health education method that will be used is the health coaching method. Objective: To determine the effect of providing health coaching on people's willingness to vaccinate in the work area of the Matangnga Health Center, Polewali Mandar Regency. Methods: The research design used was experimental research with a one-group pretest-posttest research design. Population In the study, namely all people over the age of 18 years, amounting to 3,444 people with a sample of 20 respondents, Sampling was done using the multistage sampling technique. The data collection tool used in this study was a questionnaire consisting of 17 statement items. Results: The normality test of the data using the Saphiro Wilk test showed that the data was normally distributed, and then the data was analyzed using the paired t test with the results of the p value of 0.000 <0.05. Conclusion: The results of the analysis of community attitudes towards the implementation of vaccination before and after the provision of health coaching showed that there was an effect of providing health coaching on the community's willingness to vaccinate in the work area of the Matangnga Health Center, Polewali Mandar Regency. Suggestion: It is hoped that this health coaching intervention can be developed further and can be used as a method for providing health education.
Case Study of Congklak Play Therapy for Children to Improve Social Interaction Due to Gadget Addiction
Authors: Firmansyah Andan , Setiawan Henri , Ahmad Nizar
Published: November 2023

Objective: To see the effectiveness of congklak play therapy in increasing social interaction in children because of gadget addiction.
Method: The research design used is a case study research method with a descriptive research type. The research subject used was a school-age child client with social interaction problems due to gadget addiction.
Result: Subjectively, the client experiences an increase in interaction with the people around him and a decrease in the intensity of his use of gadgets. Clients can better control their emotions, and there is an increase in learning. Likewise, objectively, the client seems to be able to control his emotions and often interacts with the people around him.
Conclusion: After doing research on An. M., the data obtained by the client's mother complains that the client rarely interacts with other people; the client often plays gadgets until he forgets the time; and when the gadget is taken, he often gets angry. The client's mother gets information from the client's school teacher that the client is less cooperative while studying at school. Based on the assessment, the diagnosis that emerged was social interaction disorder. The author conducted an intervention to overcome social interaction disturbances for four days. The intervention that the author has done is to provide congklak play therapy. After the intervention, the client's signs and symptoms of impaired social interaction diminished. The client has often interacted with people around him by using his gadget a little less.
Faktor – Faktor yang Berhubungan dengan Perilaku Pemilihan Tempat Persalinan di Wilayah Kerja UPT Puskesmas Muara Teweh Tahun 2022
Authors: Purwani Retno Endah
Published: November 2023

Penurunan ngka kematian Ibu dan Bayi masih menjadi prioritas program Kesehatan di Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan pemilihan tempat persalinan di wilayah kerja Puskesmas Muara Teweh. Penelitian ini merupakan penelitian Kuantitatif dan Jenis penelitian adalah Observasional Analitik. Pendekatan yang digunakan adalah pendekatan cross sectional, Populasinya adalah ibu hamil trimester I,II, dan III yang ada di wilayah kerja Puskesmas Muara teweh pada bulan maret sampai mei tahun 2022 sebanyak 110 orang, Pengukuran sampel dilakukan menggunakan rumus slovin  hingga diperoleh responden sebanyak 52 orang . Hasil penelitian menunjukkan bahwa proporsi ibu yang bersedia memilih persalinan di faskes berjumlah 42 responden (80,8%), 10 responden (19,2) tidak bersedia memilih bersalin di faskes.Pendidikan hasil p value 0,085,Pekerjaan hasil p value 0,492 ,Pengetahuan hasil p value=1,000 ,Jarak rumah ke fasilitas kesehatan hasil p value=1,000, dukungan keluarga hasil p value=0,043. DIsarankan kepada kepala Puskesmas Muara Teweh dan jajarannyadapat  meningkatkan cakupan persalinan di fasilitas kesehatan ,Disarankan kepada semua bidan desa untuk memberikan penyuluhan atau konseling pada ibu terutama ibu trimester III tentang pemilihan tempat persalinan yang aman sehingga dapat menghindari komplikasi pada ibu dan bayi.
FEMALE BROODSTOCK SIZE AND MATERNAL EFFECTS ON PROGENY OF Clarias gariepinus (BURCHELL 1822)
Authors: EGWENOMHE M. , OTUTU H.
Published: November 2023

Catfish farmers have been enduring having to spawn with very big females at high cost avoiding medium and small sizes. The relationship between female broodstock weight and the growth rate of progeny has been a major concern among catfish producers. To examine the impact of different female broodstock sizes on the reaction to growth of the fish seed, induced breeding of the study fish was done. The experiment was designed a completely randomized design (CRD) made of three treatments replicated three times. The treatment were three categories of weight of broodstocks as Treatment I (1000g (Treatment I or Small size), Treatment II (1500g or Medium size) and Treatment III (2500g or Large size). There was no significant fluctuation in the physico-chemical parameters of the water. There was no significant difference in the fry survival among Treatments (P>0.05). The maternal effect on growth of the study fish was 10.5 weeks of culture as Treatment 11 fingerlings then grew fastest. At the end of 40 weeks culture period there was significant difference (P<0.05) in the final weight of the table fish (1231.67 g, 1156.67g, and 1006.67g, for Treatment 11, Treatment 111, and Treatment 1, respectively). Overall, the results of these growth evaluations showed that the selected group had improved growth performance. Medium sized female broodstock can therefore deliver substantial genetic improvements in induced breeding of the study fish.
Cultural Diversity and Youth Leadership Development in Nigeria
Authors: E.A. Adelakun , R.I. Obassa , A. Atowoju , O. Afolabi , A.O. Adelakun
Published: November 2023

One of the important characteristics of culture is diversity. This makes every nation of the world a unique entity. Rather than a blessing, cultural diversity has become a tool of oppression, domination, nepotism, injustice, disparity and discrimination in the hands of political actors and influential citizens in Nigeria. In the fight against police brutality that gave birth to a dramatic event tagged “End Sars Protest” on 20th December 2020, Nigerian youths demonstrated unity in diversity. On the contrary, the same youths are major instruments of various secessionist movements and agitating groups such as Indigenous People of Biafra (IPOB), Movement for The Actualization of Sovereign State of Biafra (MASSON), The Emancipation of Niger Delta (MEND), and Yoruba Nation. What a paradoxical situation! Against this background, this study focused on youth’s awareness of Nigeria's cultural diversity and its implication for leadership development. The study explored social leadership development theory as a theoretical framework while adopting descriptive survey research design and structured questionnaires to gather information. The population for the study is comprised of the members of the Coalition of Nigerian Youth on Security and Safety Affairs (CONYSSA) alongside the National Youth Council of Nigeria (NYCN). As a result, the study adopted a purposive stratified random sampling method to select a specified number of respondents from each youth organisation within the coalition and National Youth Council of Nigeria. Then, the data collected were analysed by Microsoft Data Analysis Tool Pack and Integrated with Microsoft Excel for easy display and graphical illustration. From the findings, the study recommends that youth organisations in Nigeria should adopt a cultural approach to leadership development in their training schemes. Also, the government of the Nigerian public and private sectors should make a policy of cultural inclusion and create a sensitisation platform to educate people on the uniqueness of Nigeria's cultural diversity.
Clinical Features of Subjective Cognitive Decline in The Early Stages of Alzheimer’s Disease
Authors: Kotsiubinskaya J. V. , Mikhailov V. A. , Kazakov A. V.
Published: November 2023

Subclinical stage of the disease precedes the clinical stage of moderate cognitive decline in Alzheimer's disease (AD). Subjective cognitive decline (SCD) — a condition in which the level of cognitive function habitual for the subject gradually begins to decrease. In 2021, researchers from the National Institute on Aging and the Alzheimer's Association (NIA-AA) clinical criteria for the diagnosis of SCD have been proposed, as well as features that increase the probability of preclinical stage AD in patients with moderate cognitive impairment have been identified. Patients should be offered a complex of examinations — questionnaires regarding the impact of memory impairment on current cognitive activity (forgetfulness, searching for things, difficulty finding words, etc.), testable self-report of cognitive dynamics, neuropsychological testing and diagnosis of pathopsychological changes such as depression and anxiety. It would appear that counselling in the form of interviews and/or testing of persons able to provide relevant information about the patient should be included in the examination of patients with complaints of memory disorders, regardless of their degree of severity. It may be necessary to conduct a survey on the patient’s daily activity, ability to self-service (score, orientation, planning, control and so on), as well as to obtain information about any memory-related changes that have become visible to others, because it is the data from the partner/relative that increase the predictive value of the diagnostic. The modern approach to the study of cognitive functions in elderly people without dementia in the long-term is certainly able to help identify people with a high risk of developing AD.
Candidate Genes Associated with the Course of Epilepsy in Cerebral Palsy: Remission or Refractoriness
Authors: Sokolov P. L. , Chebanenko N. V. , Mednaya D. M. , Arkhipov V. V.
Published: November 2023

Epilepsy often accompanies congenital cerebral palsy (CP). Canalopathies can be the cause of congenital epilepsy. The aim of the study is to determine the influence of various determinants on the course of epilepsy. Materials and methods: The results of clinical and genetic analysis of 136 cases of cerebral palsy (CP) with epilepsy are presented. The patients were divided into groups according to the syndromes according to the classification of CP (Panteliadis and R. Korinthenberg, 2005). Epileptic syndromes were divided into three groups: focal childhood epilepsy with structural brain changes and benign epileptiform discharges (BEDC) in EEG - 41 children (30.1%), structural focal epilepsy - 37 children (27.2%), epileptic encephalopathies 58 children (42.7%). Pathogenic variants in genes were confirmed by next generation sequencing (NGS) Sanger methods of venous blood. Results. Remission was more difficult to achieve in patients with determinants of regulation of general aspects of cellular metabolism, mitochondrial function, cytoskeleton formation and function, and transport across the outer membrane. The need for polypharmacy was in the groups that regulate the function of mitochondria, the formation and functioning of the cytoskeleton, and the regulation of membrane excitability. Conclusion. Determinant analysis provides a better understanding of the mechanisms of patient responsiveness to anticonvulsant therapy. The determinant of mitochondrial function most significantly affects its effectiveness. Probably, the violation of energy metabolism in the cell neutralizes the stabilization of the neuronal membrane under the influence of anticonvulsants. The determinant of the formation and functioning of the cytoskeleton, according to our preliminary data, is associated with the formation of malformations of the brain. In this case, the refractoriness of epilepsy can be secondary and determined by the severity of structural changes in the brain.
Clinical Features of Essential Tremor in the Two Ethnic Groups
Authors: Govorova T. G. , Popova T. E. , Tappakhov A. A. , Andreev M. E.
Published: November 2023

Objective: The aim of the study was to study the clinical features of essential tremor (ET) in residents of the Republic of Sakha (Yakutia) in various ethnic groups.Material and methods. The study involved 53 patients with an established diagnosis of essential tremor. All patients underwent a detailed neurological examination with a quantitative assessment of the severity and severity of tremor, as well as the degree of maladjustment and activity in everyday life using unified scales.Results and Discussions. It was revealed that the clinical variant of essential tremor-plus, associated with a more severe course and disability of patients. In the representatives of the Russian ethnic group, with the classic version of essential tremor, a combination of head tremor and hand tremor is observed, as well as a more rapid progression of disease symptoms. Representatives of the Yakut ethnic group in the clinical picture of essential tremor-plus are statistically significantly more likely to have a dystonic head position.Conclusion. Clinical variability of essential tremor with differences in the ethnic aspect in the rate of progression and in the frequency of the combination of action tremor with dystonic head position was demonstrated.
The effect of a night shift nap on post-night shift performance, sleepiness, mood, and first recovery sleep: A randomized crossover trial
Authors: Patterson P Daniel , Hilditch Cassie J , Weaver Matthew D , Roach David GL , Okerman Tiffany S , Martin Sarah E , Patterson Charity G , Weiss Leonard S
Published: November 2023

OBJECTIVES: This study aimed to test the effect of a 30-minute nap versus a 2-hour nap opportunity taken during a simulated night shift on performance, fatigue, sleepiness, mood, and sleep at the end of shift and during post-night shift recovery.

METHODS: We conducted a randomized crossover trial of three nap conditions (30-minute, 2-hour, and no-nap) during 12-hour simulated night shifts. We tested for differences in performance, fatigue, sleepiness, mood, and sleep during in-lab and at-home recovery. Performance was measured with the Brief Psychomotor Vigilance Test (PVT-B). Subjective ratings were assessed with single-item surveys.

RESULTS: Twenty-eight individuals consented to participate [mean age 24.4 (standard deviation 7.2) years; 53.6% female; 85.7% Emergency Medical Services clinicians]. PVT-B false starts at the end of the 12-hour night shift (at 07:00 hours) and at the start of in-lab recovery (08:00 hours) were lower following the 2-hour nap versus other conditions (P<0.05). PVT-B response time at +0 minutes post-recovery nap was poorer compared to pre-recovery nap for the no-nap condition (P=0.003), yet not detected for other nap conditions (P>0.05). Sleepiness, fatigue, and some mood states were lower at most hourly assessments during the in-lab recovery period following the 2-hour nap condition compared to the other conditions. Sleep during recovery did not differ by duration of night shift nap.

CONCLUSIONS: A 2-hour nap opportunity versus a 30-minute or no-nap opportunity is beneficial for performance, alertness, and mood post-night shift. No differences were detected in sleep during recovery.
Thực trạng quản lý hoạt động bồi dưỡng năng lực nghề nghiệp cho giáo viên các trường mầm non quận Ninh Kiều, thành phố Cần Thơ
Authors: Lê Ngọc Tuyền
Published: November 2023

Trong những năm học qua, được sự quan tâm chỉ đạo của các cấp các ngành, các trường mầm non trên địa bàn quận Ninh Kiều, thành phố Cần Thơ đã thực hiện nhiều biện pháp nâng cao chất lượng, hiệu quả hoạt động bồi dưỡng năng lực nghề nghiệp cho giáo viên mầm non. Tuy nhiên, quá trình quản lý hoạt động này vẫn còn một số bất cập như: nội dung bồi dưỡng chưa chú trọng vào nhu cầu và năng lực của giáo viên, chưa phân tích điểm mạnh, điểm yếu của đội ngũ để xây dựng kế hoạch bồi dưỡng phù hợp. Nghiên cứu này tiến hành khảo sát ý kiến của 25 cán bộ quản lý và 75 giáo viên đến từ 07 trường mầm non trên địa bàn quận Ninh Kiều, thành phố Cần Thơ nhằm làm rõ thực trạng công tác quản lý hoạt động bồi dưỡng năng lực nghề nghiệp cho giáo viên trên địa bàn. Kết quả nghiên cứu làm cơ sở để đề xuất các biện pháp quản lý phù hợp, góp phần nâng cao chất lượng quản lý hoạt động bồi dưỡng năng lực nghề nghiệp cho giáo viên mầm non trên địa bàn quận Ninh Kiều, thành phố Cần Thơ.
自我揭露行為在非結構團體諮商歷程的社會網絡關係發展之個案研究
Authors: 刑志彬 刑志彬 , Chih-Pin Hsing 許育光 , Yu-Kuang Hsu 田秀蘭 , 范中豪 范中豪
Published: November 2023

鑒於團體諮商工作模式於華人心理健康的協助逐漸受到重視，本研究聚焦在探索團體現象，藉由非結構諮商團體歷程的社會網絡分析，理解團體歷程領導者與成員的關係結構，從人際結構促進未來團體諮商工作介入之參考。本研究採個案研究法，對於一個非結構團體的歷程進行質性與量化的分析。本研究由七個非結構諮商團體呈現的結果，透過團體成員在成人心理健康量表前後測的改變程度，篩選最具效果的團體進行深度的個案研究分析；團體歷程的脈絡主題編碼、參與者自我揭露行為編碼，將團體歷程的數據進行社會網絡分析與討論。研究結果發現非結構諮商團體的介入對團體成員具有正向的效果，在「團體歷程脈絡主題」、「領導者位置」、「核心成員意義」、「邊陲成員意義」、「整體自我揭露行為」、「領導者的發話量」、「焦點成員重複性」等面向皆存在社會網絡分析的圖論特性。本研究對團體歷程的權力議題、關係結構進行分析與討論，並針對諮商團體後續研究、領導者培育、團體實務能力進行建議。

 

With the increasing popularity of group counseling, it becomes imperative to comprehend the development of group relational structures between leaders and members. However, due to the scarcity of research on the interaction analysis of group dynamics, this case study aimed to examine the relational structure of an unstructured counseling group using social network analysis. From seven unstructured counseling groups, the case study selected the one with the best performance based on the participants’ score changes on the Adult Mental Health Scale. Through visual analysis, significant changes in the interaction structures between group leaders and two types of members were revealed. Additionally, mathematical analysis yielded patterns in the number of themes, counts of self-disclosure actions, and levels of interaction intensity. Both qualitative and quantitative findings implicitly reflected changes in group cohesion throughout the various process stages. As a result, this study offers practical implications for training group leaders on different group process issues, including the transition of authority and members’ roles and functions at various group stages. Furthermore, the research provides valuable insights for the future exploration of counseling groups.

 
人體生物資料庫管理條例之修法芻議
Authors: 何之行 何之行
Published: November 2023

人體生物資料庫為發展精準醫療之基石，考量科技發展之快速變遷、大數據與人工智慧於醫療領域之應用，人體生物資料庫管理條例之修訂亦將引領我國健康資料治理法治之建立。本文將分析探討目前人體生物資料庫管理條例之重要修訂內容，亦盼能完善我國人體生物資料庫之相關治理規範。

 

Biobanks play a pivotal role in advancing precision medicine, given the swift evolution of technology, the utilization of big data, and the integration of artificial intelligence. The proposed amendments to the Human Biobank Management Act are poised to establish a robust legal framework for health data governance in Taiwan. This article will delve into the significant revisions and regulations within the Human Biobank Management Act, offering recommendations with the aim of enhancing the governing processes pertaining to biobanks.

 
指叉狀電極應用於透明導電膜之溫升研究
Authors: 周柏漢 周柏漢 , 余志鴻 余志鴻 , 許世昌 許世昌 , Shih-Chang Shei 林男明
Published: November 2023

在這篇論文中，基於銦錫氧化物(ITO)加熱裝置依然存在許多問題，為了解決問題，本論文使用不同比例的指叉狀電極遮罩來蒸鍍電極在ITO上，並對其做深入研究。
在我們會使用到熱蒸鍍機，並以鋁作為電極，蒸鍍在ITO玻璃上，使用不比例的指叉狀遮罩來蒸鍍鋁於ITO的系統，其中指叉狀電極的比例分別為為1:1(sample02)，2:1(sample03)，3:2(sample04)，以及無指叉狀的電極(sample01)，而在這次的實驗中，我們所改變的參數只有指叉狀電極的比例，其他的參數則沒有改變，鋁圈數量是固定四圈，蒸鍍環境也都是固定的真空值，蒸鍍電流則是固定在70A，以便探討不同電極的影響。
在蒸鍍結束後，我們分別對不同比例指叉狀電極的樣品進行電學特性以及溫升的量測，結果表明1:1的電阻值約為68Ω，溫升速率約為0.617°C/s，2:1的電阻值約為100Ω，溫升速率約為0.335°C/s，3:2的電阻值約為100Ω，溫升速率約為0.314°C/s，1:1的電阻值是最小的，溫升速率是最快的，相較於其它比例的樣品是最高的，在蒸鍍不同指叉狀電極的時候，並不是電極數越多越好，而要考慮有效發熱面積與其他因素。In this paper, based on the existing ITO heating device, the effect is not as good as expected. Therefore, we use different types of metal masks to evaporate the electrode on a single layer of indium tin oxide (ITO). Do in-depth research, and this experiment is mainly divided into two parts.
In the first part, we will use a thermal evaporator, and use aluminum as the electrode to evaporate on the ITO glass, and use a non-proportional interdigitated mask to evaporate the aluminum on the ITO system. The proportion of the interdigitated electrode is They are 1:1 (sample2), 2:1 (sample3), 3:2 (sample4), and non-digital electrodes (sample1). In this experiment, the only parameter we changed was the fingers. The ratio of the shaped electrodes and other parameters have not changed. The number of aluminum circles is fixed four circles, the evaporation environment is also a fixed vacuum value, and the evaporation current is fixed at 70A to explore the influence of different electrodes.
After the evaporation, we measured the electrical characteristics and temperature rise of samples with different ratios of interdigitated electrodes. The results showed that the 1:1 resistance value is about 68Ω, and the temperature rise rate is about 0.617°C/s. 2:1 resistance value is about 100Ω, temperature rise rate is about 0.335°C/s, 3:2 resistance value is about 100Ω, temperature rise rate is about 0.314°C/s, 1:1 resistance value is the smallest Yes, the temperature rise rate is the fastest, which is the highest compared to other proportions of samples. When evaporating different interdigitated electrodes, it is not that the more electrodes are better, but the effective heating area and other factor.
Physical, physicochemical, and functional technological properties of flour produced from gueroba fruit pulp
Authors: JORGE Ana Paula Pereira , OLIVEIRA Daniel Emanuel Cabral de , FERREIRA JUNIOR Weder Nunes , SILVA Lígia Campos de Moura , RESENDE Osvaldo , ROMANI Viviane Patrícia
Published: November 2023

The Cerrado biome has a variety of fruit species less explored, such as gueroba. Flour is obtained by dehydration processes and is an alternative in the food industry for utilizing by-products. The objective of this study was to analyze the physical, physicochemical, and functional technological characteristics of flours from gueroba (Syagrus oleracea Becc.) fruit pulp produced by oven drying at different temperatures (40, 50, 60, and 70°C) and by lyophilization. The flour produced by lyophilization of gueroba fruit pulp showed a lighter color. According to the results obtained for the parameter L, it can be suggested that the increase in the temperature used for drying gueroba fruit pulp does not tend to promote browning of the product, the greater amount of soluble solids, higher water absorption index, and lower solubility in milk, lower emulsifying activity, and greater foaming activity. All flours showed pH values between 6.11 and 6.22. Also, the ash contents of the FEG40, FEG50, FEG60, FEG70, and FEGL samples did not differ between treatments, showing mean values of 5.67, 5.39, 5.73, 4.86, and 5.85 g 100 g–1, respectively.
Physicochemical and sensory characterization of okara obtained by two different processes and the study of its use as breaded food
Authors: KNIAZEV Maximiliano , GÁMBARO Adriana , VIEITEZ Ignacio
Published: November 2023

Soybean residue, known as okara, is a byproduct of soymilk production with varying compositions based on the production process. This study explored the characteristics of fresh and dried, disc-milled, and all-metal hammer-milled okara derived from soy crops in Uruguay through different techniques, including physicochemical, microbiological, and sensory analyses. Specifically, dried disc-milled okara was used in making breaded tofu steak, and the sensory traits and oil absorption of the fried product were examined when bread crumbs were substituted with okara in proportions of 0, 25, 50, 75, and 100%. The production process affected moisture, protein, fiber, and oxidative rancidity. Dried samples showed differences in smell, crispness, and particle size, while the drying process reduced microbial load and total polyphenols but enhanced lightness, redness, and yellowness. All samples exhibited a similar fatty acid profile, mainly C18:2. Increasing okara content in breading enhanced the color and smell of fried steaks. Interestingly, there was no significant difference in fat content between the 0 and 100% okara substitutions. This study concludes that dried okara, rich in fiber, protein, and essential fatty acids, presents potential as a functional food for human consumption. It also serves as a sustainable and nutritious breading substitute, offering an alternative to conventional ingredients.
Pandemic Visuality
Authors: Mirzoeff Nicholas
Published: November 2023

This piece addresses the politics of immunity, in terms of both immunity from state action and immunity to viruses in the general crisis of 2020. Paying particular attention to the connections between white supremacy and these immunopolitics, biopolitics and necropolitics, the essay examines a series of specific moments in the psychodrama of US life across 2020.
From "Contagion" to Covid
Authors: Schweitzer Dahlia
Published: November 2023

Proliferating for the last twenty-five years, outbreak narratives have now reached epidemic proportions. From 28 Days Later to The Walking Dead, Outbreak to Contagion, films and television shows are filled with zombie viruses, bioengineered plagues, and disease-ravaged survivors. Not only have outbreak narratives infected public discourse and affected the way we view the world, but they have, especially right now, impacted global responses to COVID-19. The way infectious viruses are appropriated by Hollywood provides insight into the viruses themselves and the world we live in. After all, few things reflect social trends and anxieties like film and television. Alarmingly, outbreak narratives are even used as “how-to manuals” of sorts. For instance, as COVID-19 took hold, journalist Mike Stuchbery tweeted that crisis response teams were reading World War Z by Max Brooks (a fictional account of a zombie plague) as a study in the effects of epidemics. My chapter examines film and television outbreak narratives, studying how the repetition of characters, images, and story lines has produced a formulaic narrative that reflects and shapes new paradigms of disease and fear, connecting those to real-life events that have unfolded worldwide over the course of 2020.