bluuebunny/crossref_metadata_2025 huggingface dataset:
Unravelling the Dynamics of Macroeconomic Variables and Infant Mortality in India Based on ARDL Model Analysis
Authors: Patterkadavan Fasalurahman P. K. , Qayed Syed Hasan
Published: November 2024

The well-being of mothers and children serves as a vital indicator of a nation’s prosperity and is influenced by a range of factors, including macroeconomic variables such as Gross Domestic Product (GDP), unemployment, inflation, income, education, and healthcare expenditure. Escalating inflation precipitates higher food prices, amplifies household living costs, and diminishes purchasing power, consequently exerting a substantial impact on individuals’ nutritional and physical health. This study aims to examine the correlation between macroeconomic variables, specifically GDP per capita, Consumer Price Index (CPI), unemployment, and infant mortality in the Indian context. Despite the significance of this relationship, there exists a dearth of research on the association between macroeconomic variables and maternal and child mortality, particularly within the Indian context. Prior studies consistently underscore the indispensability of macroeconomic stability in achieving improved outcomes in maternal and child health. The analysis draws upon secondary data procured from reputable sources such as the World Bank and Reserve Bank of India (RBI), encompassing time series data about both the dependent variable, namely the infant mortality rate, and the explanatory variables. To investigate the impact of macroeconomic variables on infant mortality, the study employs the Autoregressive Distributed Lag (ARDL) Error Correction Model, which accounts for the interplay between the variables over time. Empirical findings establish the existence of long-term cointegration between macroeconomic variables and the infant mortality rate. However, in the short run, some variability in cointegration arises due to a multitude of factors, including policy interventions, demographic characteristics, and socio-cultural determinants. This study substantiates the proposition that sustaining macroeconomic stability and fostering economic growth play pivotal roles in attaining health sector objectives, particularly in emerging economies like India. Consequently, while formulating health policies, equal emphasis must be placed on measures aimed at stabilizing the economy to ensure favourable outcomes of such policies.
Factors Influencing GST Return Filing: A Study Based on Theory of Planned Behaviour among Entrepreneurs in Kerala
Authors: Krishna Swathy , Shacheendran V.
Published: November 2024

The study used the Theory of Planned Behaviour (TPB) to examine the GST return filing intention of entrepreneurs across Kerala. The extended TPB model examines the impact of attitude toward GST filing, subjective norms, perceived behavioural control, and moral obligation on compliance intention with respect to the filing of GST returns. The analysis was performed using the information gathered from 205 entrepreneurs residing in Kerala. The interconnection among the variables was examined using PLS-SEM. The results indicate that an entrepreneur’s attitude and subjective norms could enhance the certainty of GST compliance decisions, meanwhile, perceived behavioural control does not have any relevant impact on an entrepreneur’s intention to file GST returns on time. The study further delves into the least explored area by focusing on the role of moral obligation in influencing the timely filing of GST returns. The study provides evidence that tax compliance intention is positively associated with the level of moral values possessed by entrepreneurs.
Transportery kwasów tłuszczowych jako potencjalne markery diagnostyczne raka jelita grubego
Authors: Jankowski Wojciech Michał , Fichna Jakub , Tarasiuk-Zawadzka Aleksandra
Published: November 2024

Colorectal cancer (RJG) is one of the most frequently diagnosed malignant neoplasms: approximately 1.9 million new cases are reported annually. Notwithstanding the advent of techniques for the early detection of RJG and the introduction of novel therapeutic modalities, this disease remains the second leading cause of cancer-related mortality. The results of recent studies highlight the role of fatty acid transporters, including fatty acid translocase/cluster of differentiation 36 (FAT/CD36), fatty acid transport proteins (FATPs), and fatty acid-binding proteins (FABPs), in the pathogenesis of RJG. Changes in serum concentrations and in expression levels in tumor tissue may serve as promising biomarkers for the early diagnosis of the disease and/or the monitoring of its progression and the efficacy of its treatment. Moreover, the fatty acid carriers present a promising avenue for the development of efficacious therapies against RJG.
Revolucionando la auditoría y el aseguramiento: el impacto de la sostenibilidad y el uso de nuevas tecnologías en el ejercicio profesional
Authors: Minutti-Meza Miguel
Published: November 2024

El documento tiene un doble propósito: examinar tanto la creciente importancia de la auditoría en los informes de soste­nibilidad (ESG), como la adopción de tecnologías emergentes en el proceso de auditoría. Mediante la revisión de distintos estudios de organismos profesionales y de investigación se identifican las prácticas de divulgación y aseguramiento de la información ESG. En paralelo, se discute el uso de las tecnologías emergentes, como los modelos de lenguaje (LLM), y las transformaciones que generan en la auditoría, y se concluye que la divulgación de la información ESG gana terreno en la rendición de cuentas de las empresas, pero que existe una disparidad significativa en cuanto a su asegu­ramiento. A su vez, aunque las tecnologías emergentes permiten analizar grandes volúmenes de datos con mayor rapidez y precisión, el juicio profesional sigue sien­do esencial para la interpretación y toma de decisiones en escenarios complejos. Finalmente, la incorporación de estas tecnologías en la formación de los auditores resulta determinante para potencializar la eficiencia en los procesos de auditoría, aunque aún se requiere mayor investigación sobre su costo-beneficio y grado de adopción en la práctica contable.
Contabilidad de Gestión Ambiental: avances conceptuales para construir una contabilidad para la sustentabilidad
Authors: Arias Suárez Juan David , Cano Mejía Vanessa
Published: November 2024

Este artículo tiene por objeto analizar las perspectivas concep­tuales con las que ha sido abordada la categoría de Contabilidad de Gestión Ambiental (CGA) en las revistas especializadas de las bases de datos Scopus y Web of Science. Metodológicamente el artículo tiene un enfoque cualitativo que se apoya en una Revisión Sistemática de la Literatura (RSL) de 283 documentos del área temática publicados en 156 revistas científicas especia­lizadas, con una focalización temporal entre 2000-2023. Como resultados y contribuciones se presentan datos bibliométricos de los documentos, sus temáticas asociadas y se realiza un análisis cualitativo de las perspectivas conceptuales que subyacen a las categorías estudiadas para construir una contabilidad para la sustentabilidad. Como hallazgo se identificó que la CGA es una temática emergente en un enfoque combinado de datos financieros, de costos y de gestión para aumentar la eficiencia organizacional, reducir el impacto y los costos ambientales. Conceptualmente la mayoría de los documentos revisados utilizan los conceptos seminales sin discutir su esencia e impactos, evidenciando disputas casuísticas y generando una tendencia utilitarista del campo.
The effect of blockade of the renin‑angiotensin‑aldosterone system on skin microcirculation in rats with impaired renal function
Authors: Ivanova G. T. , Khasun M. Kh. , Parastaeva M. M. , Rumyantsev A. Sh. , Beresneva O. N.
Published: November 2024

The renin-angiotensin-aldosterone system (RAAS) is involved in the regulation of kidney function and blood pressure (BP). In renal dysfunction, hyperactivation of the RAAS leads to an increase in BP and impaired permeability of the nephron glomerular filter. Blockade of the RAAS is one of the methods of nephroprotection. Objective. To compare the effect of an angiotensin-converting enzyme inhibitor (IACE), angiotensin I receptor blocker (ARB), and a selective slow calcium channel blocker (BCC) on the functional state of the microvasculature of the skin of rats with nephrectomy (NE), fed with a high-salt diet (HS). Design and methods. Five groups of Wistar rats were studied. The SO group: sham-operated animals that received a standard diet; the HS+NE group: rats with ¾ NE and HS (4 % NaCl); HS+NE+Ler-, HS+NE+Lis-, HS+NE+Los-groups: rats with ¾ NE and HS, that were treated with the BCC lerkanidipin (Ler, 3 mg/kg), IACE lisinopril (Lis, 30 mg/kg) or the ARB losartan (Los, 10 mg/kg), respectively. After 4 months, a study was performed using laser Doppler flowmetry (LDF). Results. In rats of the HS+NE group, uremia is accompanied by an increase in BP (by 16,9 % compared to the SO group). The treatment with IACE and ARB in rats with NE and HS prevents the rise in BP, while BCC does not reduce BP. The LDF-study showed that the increased intensity of initial skin perfusion in rats of the HS+NE group (7,2 ± 0,3 compared to 6,5 ± 0,2 p. u. in the SO group) is not corrected by BCC (6,9 ± 0,3 p. u.), but is reduced by the use of IACE (6,4 ± 0,2 p. u.) and ARB (6,1 ± 0,2 p. u.). Wavelet analysis showed that the increase in tonic effects on blood vessels in the endothelial, neurogenic and myogenic regulatory circuits, characteristic of renal dysfunction, decreases with the use of all studied drugs. RAAS blockade in rats with ¾ NE and HS does not prevent a decrease in the reactivity of skin microvessels to acetylcholine (ACh), and the use of BCC restores the response of skin blood flow to ACh to the control level. Conclusions. In Wistar rats, NE in combination with HS leads to an increase in BP, an increase in tonic effects on skin microvessels in the endothelial, neurogenic and myogenic ranges, as well as a decrease in the reactivity of skin blood flow to ACh. Inhibition of the RAAS by the treatment of IACE and ARB prevents the increase in BP, but does not improve the reactivity of skin microvessels. The use of BCC in rats with NE and HS does not reduce BP, but improves the reactivity of skin microvasculature to ACh.
Arterial hypertension: the current state in Russia and in the world. Review. Part II
Authors: Ismailova M. A. , Afanasyeva A. D. , Garbuzova E. V. , Ragino Yu. I.
Published: November 2024

The prevalence of arterial hypertension (HTN), which is one of the most important risk factors (RF) for cardiovascular diseases (CVD), is still increasing, which represents a global problem for world health, because for many decades CVD have occupied a leading position in the structure of mortality throughout the world. This article reviews the main epidemiological studies available by the end of 2023, which analyzed various indicators of HTN both in Russia and around the world, with the aim of developing an understanding of time trends in the prevalence of HTN. This article also analyzes the main RF for HTN and sex differences, because it is known that in men the prevalence of HTN is traditionally higher than in women in Russia, and special attention is paid to indicators such as adherence to therapy, effectiveness and control of HTN.
“You Started the Dispute” – an Essential Argument in Controversies Typical of Oral Cultures and the Discoursive Blueprint of the "Iliad"
Authors: Zieliński Karol
Published: November 2024

The paper argues that in the imagery found in the narrative context of the Iliad, the image of public debates is involved. Especially the argument “you started the dispute” is emphasized because it is connected with the concept of blame attributed to Paris and all the Trojans. Under the influence of such works like Graeber and Wengrow (2021), that shed a new light on the prehistory of mankind, I postulate a change in the paradigm of the interpretation of the Homeric world. I believe it would be much more comprehensible if interpreted as expressing egalitarian relations. After all, social and political circumstances described in the Iliad correspond to the phase in which hierarchy is only an increasing tendency. Comparisons drawn from other egalitarian cultures indicate how significant it is who started the dispute and how this argument can be cancelled. In the blueprint of the Iliad, however, Paris’ blame defines the meaning of the Trojan story and, therefore, the indictment that it was Alexander who started the dispute plays a paramount role.
Przedświt: fascynacja architekturą mykeńskiej i archaicznej Grecji w Niemczech schyłku XIX i początków XX wieku
Authors: Makała Rafał
Published: November 2024

At the beginning of the 20th century, German architecture saw a turn towards the art of antiquity, which was partly a reaction to the profusion of decoration in late historicism and Art Nouveau. However, the so-called Reformarchitektur was interested not only in classical antiquity (and the art of classicism and neoclassicism), but also in earlier periods, especially Mycenaean art. This was, of course, related to the discoveries in Troy, Mycenae and Tiryns, but the social and political context of the time was equally important. One of the foundations on which the national identity of the Germans in the 19th century was based was the myth of the ancient Germans, who were supposed to be characterized by courage, sincerity and natural morality. According to the creators of this idea (F. Avenarius, J. Langnehn, A. Haupt, G. Kossinna et al.), the Germans, next to the Greeks, were one of the original peoples of Europe (Urvolk), sharing ideas and artistic forms. In the north of the continent, they were allegedly preserved longer than in the Mediterranean area because the Nordic nations did not take part in the development of mimetic art. Consequently, it was believed that in the architecture of the Mycenaean period, as well as in buildings from the Homeric and archaic periods (as well as in Etruscan and ancient Roman buildings), we could find forms typical of the unpreserved Nordic architecture, destroyed in the process of Christianization. Therefore, Mycenaean and archaic architecture became the subject of interpretation in the spirit of nationalism, perceived, however, in a broader sense than just the framework of one nation. This was related to the category of “Nordic nations” as well as an even broader vision of the “primordial peoples of Europe”. These views and research became one of the inspirations for the architecture created at that time with reformatory, modernizing ambitions.
Aktywność G. Juliusza Cezara w Hiszpanii w latach 60-tych I wieku przed Chr.
Authors: Ładoń Tomasz
Published: November 2024

In the sixties Caesar visited the Further Spain twice, first as quaestor (69–68), then as governor (with the rank of proconsul) in 61. Both stays are extremely important from the point of view of Caesar’s career and the activities carried out in the province. The author of the article examines Caesar’s activities in Spain: both his military actions and his administrative and financial activities. He looks at Caesar’s political connections, both those that brought him to Spain and those he managed to establish in the province.
"Catalogus clarorum Hispaniae scriptorum" Waleriusza Andrei jako źródło informacji o recepcji literatury antycznej
Authors: Witczak Agnieszka
Published: November 2024

Valerius Andrea’s work Catalogus clarorum Hispaniae scriptorum contains the names of all Spanish authors whose works Valerius managed to find in German libraries. This catalog is therefore a valu­able source not only for learning about authors writing in Latin, but also for learning about the fate of Latin literature from antiquity to the 17th century, at the beginning of which this work was written.
El paradigma de Pigmalión en el poema 14 de Pablo Neruda
Authors: Martínez Sariego Mónica María
Published: November 2024

The article discusses the possible influence of Ovid on poem 14 of Veinte poemas de amor y una canción desesperada (1924) by Pablo Neruda, specifically through the paradigm of Pygmalion (Met. X, 243-297), which the Chilean poet uses to develop themes of love, creation, and transformation. The connection is evident in the characterization of the lyrical subject as lonely and misanthropic, but also in relation to the poetic addressee. The beloved is lavished with gifts and attentions, and the lyrical subject wishes to make her bloom. The comparative analysis, besides confirming the presence of a new classical hypotext in Veinte poemas de amor y una canción desesperada, suggests new avenues of interpretation of the collection, especially in the cycle dedicated to Marisombra, whose passivity is akin to Pygmalion’s statue. This contribution can contribute to a better understanding of Neruda’s work and emphasize the relevance of the classical tradition, never sufficiently highlighted, in his poetry.
Locuciones latinas y variación lingüística en el español del siglo XXI
Authors: López González Antonio María
Published: November 2024

The objective of this article is to analyze the effect of linguistic variation in Latin idioms in Spanish, invariable lexical units, from a normative point of view. To do this, first of all, we define and distinguish Latin idioms within Latinisms in the Spanish language. Afterwards, we present its typology and main structures, according to Sánchez Martínez (1993). Later we discuss the normative treatment of Latin phrases by RAE, not exempt from some contradictions and changes in criteria over time. In the analytical part, we synthesize the meaning and normative use of 32 widely used Latin idioms. Finally, based on the linguistic corpus CORPES XXI, we carry out a quantitative analysis of the linguistic variants of the selected Latin idioms, with an example of each variant.
The problem-based approach in mathematics teaching and its impact on mathematical problem-solving performance
Authors: Doz Daniel , Cotič Mara , Cotič Nastja
Published: November 2024

Problem-solving is a key aspect of mathematics instruction. Although it is part of several national curricula, its implementation is still being vastly explored. This research aimed to investigate and update the existing educational process in mathematics teaching in primary education by designing and evaluating an experimental model of problem-based mathematics education. The study used a pedagogical experiment, with a sample of 240 pupils in Grade 3 from four selected Slovenian primary schools. The results showed that the use of an experimental model of problem-based learning had a statistically significant effect on pupils’ mathematics achievement in all the domains of mathematics in terms of numbers, geometry, logic, and set theory. The study suggests that modern school reforms should focus on problem-based mathematics instruction as a means of achieving meaningful and lasting knowledge in students.
Keywords: Achievement; experiment; mathematics; problem-solving; problem-based instruction.
Potensi Sediaan Nanokitosan Ekstrak Daun Mimba (Azadiractha indica A. Juss) terhadap Fertilitas Tikus Putih Betina (Rattus norvegicus)
Authors: Sitepu rlalana Hansel Christian , Ningtias Putri Lestari , Putra Alfisah Gama , Damayanti Adelia Brilian , Darsono Aurel Elizabeth , Sitasiwi Agung Janika , Suprihatin Teguh
Published: November 2024

The potential of neem leaves as an antifertility compound in female rats needs to be studied more thoroughly because they contain various toxic secondary metabolites. This study was aimedsto examine the effect of exposure to nanochitosan ethanol extract of neem leaves as an antifertility compound on female white rats. Extraction and manufacture of nanochitosan using 70% ethanol solvent. A toal of 24 adult female wistar rats aged 2-3 months were used as experimental animals. This study used a completely randomized design (CRD) with three treatments and eight replications. The treatments given were P0 (aquadest), P1 (ethanol extract of neem leaves at a dose of 14 mg/kgBW/day), P2 (a nanochitosan preparation of ethanol extract of neem leaves at a dose of 14 mg/kgBW/day). The treatment was given orally for 21 days. Observation of fertility was carried out by observing the corpus luteum and measuring the rate of pregnancy through mating tests. Data was analyzed by using Analysis of Variance.The results showed that the highest Gonadosomatic Index(GSI)score was found in the P1 group because it was influenced by gonad weight and individual response variations. Exposure of nanochitosan preparations of neem leaf extract to the number of corpus luteum showed a difference with the lowest result found in the P2 group. The lowest success rate of embryo implantation was found in treatments P1 and P2 with embryos not developing or resorption. It can beconcluded that exposure to nanochitosan preparations of ethanol extract of neem leaves has a very effective antifertility effect on female white rats.
Effects of resistant starch of mixed tubers snacks on glucose metabolism, leptin, visceral fat and body mass index in type 2 diabetes mellitus (T2DM)
Authors: Hidayat Jenny , Sunarti . , Mustofa . , Sadewa Ahmad Hamim
Published: November 2024

Resistant starch could lower blood glucose, decrease adipocyte in adipose tissue and affect satiety hormones such as leptin. Tubers and pumpkin have high content of resistant starch, but their effectiveness to type 2 diabetes mellitus (T2DM) has not been known clearly. This research was conducted to determine the effectiveness of snack consumption made from tubers and pumpkins to BMI, visceral fat, glucose and leptin levels in the blood of T2DM patients and the correlation between the variables. The research method was pre-post clinical trial. Sixteen T2DM patients were in treatment (RS) and control groups. Subjects in RS group were given snack twice daily for 4 weeks. After following wash out process for 4 weeks, the same subjects was continued as subjects’ control. Paired t-test and/or Wilcoxon-test was used to analyze the differences between values before and after treatment in the group and between groups. Pearson test was used to analyze the correlation of BMI, visceral fat, glucose and leptin level. The visceral fat was increased in RS group (p=0.04) after 4 weeks consuming snack but decrease in control group (p=0.04) without significant change of BMI. Leptin level was decreased (p=0.00) in RS group. Blood glucose significantly decreased (p=0.01) and leptin level increased slightly in control group. Comparing the RS and control group at the end of study, there were significantly different in the variation of visceral fat in the female groups (p=0.05) and leptin (p=0.05). Visceral fat correlated with BMI in the RS and control group. In conclusion, the mixed tubers and pumpkin snack decreased the leptin level but increased visceral fat.
The difference of nasal mucosal cytology features in gas station workers compared to non-gas station workers
Authors: Rianto Bambang Udji Djoko , Kurniawan Linggawati , Sudarman Kartono
Published: November 2024

The pollutants contained in an outdoor air environment for example gasoline vapors can cause epithelial inflammation, metaplasia, and dysplasia. This study aimed to determine the difference in cytological nasal mucosa between gas station workers and non-gas station workers. This research used a cross-sectional design. There were 80 samples with inclusion criteria: aged 20-50 years, worked more than 3 months, consisting of 40 gas station workers (exposed group) and 40 non-gas station workers (unexposed group) who did not use nasal drops in the last ten days. The exclusion criteria of both groups were: 1) patients with acute rhinitis, 2) had nasal trauma, 3) had nasal surgery, 4) consume alcohol, 5) history of allergic rhinitis, and 6) refused to participate in the study. All samples performed brushing at 1/3 anterior nose inferior turbinate and cytology examination. The statistical analyses used X2 tests. From the exposed group we found 18 (45%) with inflammation, 17 samples (42.5%) with metaplasia, and 9 samples (22.5%) with dysplasia, while in the unexposed group there were 10 (20.5%) with inflammation, 4 (10.0%) with metaplasia and 2 (5.0%) dysplasia. There were statistically significant differences in nasal mucosal cytology, particularly metaplasia (p: 0.001; RP: 6.65; 95% CI: 1.78-27.01) and dysplasia (p: 0.023; RP: 5.52; 95% CI: 1.22-32.10) between both group samples. It can be concluded that there are statistically significant differences involving metaplasia and dysplasia in nasal mucosa cytology features of gas station workers compared to non-gas station workers.
Correlation between micro-RNA-21 expression and inflammation cytokine in rabbits implanted with bare metal stent with the incidence of neo intimal hyperplasia
Authors: Hariawan Hariadi , Soesatyo Marsetyawan HNE , Munawar Muhammad , Ghozali Ahmad
Published: November 2024

In-stent restenosis after stenting in vascular occurs secondary to the accumulation of smooth muscle cell and extracellular matrix. This condition is a major complication caused by the occurrence of neointimal hyperplasia (NIH). The study aimed to prove the role of miRNA-21 as a risk predictor of the NIH event in aorta of rabbits animal model who underwent bare metal (BM) type stent implantation and to know the miRNA-21 role in IL-6 and IL-8 expressions. This study was quasi experimental, coducted in Catheterization Laboratory Dr. Sardjito General Hospital Yogyakarta. Stent implantation was observed intravascular ultrasonography. Blood vessel which was already deployed by stent taken as sample for pathologic examination. Rabbit blood samples were collected on day 0, 7, and 28. Quantification miRNA-21 expression has been done with qPCR and ELISA approach. These 10 rabbits divided into two groups in which one group as control (without stent deployment, 4 models) and another group as intervention (with BM type stent deployment, 6 models). The increase in expression of miRNA-21 on the day 7 and day 28 in the intervention group compared to the control group. Neointimal hyperplasia increased in intervention group on day 7, and 28 were from mild grade to moderate, and severe respectively. In addition, levels of IL-6 and IL-8 increased on day 28 compared with on day 7. This study showed increase of miRNA-21 expression on day 7 and NIH rise from the mild to moderate. Furthermore, on day 28, that increases of miRNA-21 expression and NIH rose from to moderate to severe. The increase of miRNA-21 was also shown on day 7 and 28 followed by the increase of IL-6 and IL-8 levels.
Les inventaires forestiers au Gabon : applications à la phytogéographie
Authors: Cabaillé G. , Fontès J.
Published: November 2024

Sur la base des données disponibles, l'auteur fait une étude phytogéographique quantitative des espèces ligneuses de première grandeur qui sont les plus représentées dans la plupart des forêts gabonaises de terre ferme.Les critères adoptés dans cette étude sont l'abondance et la fréquence des espèces. Ces critères, simples à calculer, donnent une image objective et concrète de l'état actuel de la composition floristique majeure de la forêt.Ainsi, sous une apparente homogénéité globale, la forêt dense gabonaise présente, quantitativement, une hétérogénéité floristique tout à fait considérable. Deux grands groupes phytogéographiques sont distingués.
Pyrolyse des bois tropicaux. Influence de la composition chimique des bois sur les produits de distillation
Authors: Pétroff Georges , Doat Jacqueline
Published: November 2024

Six échantillons de bois ont été pyrolysés en laboratoire : trois mélanges tropicaux composés de bois riches en lignine, riches en extraits ou riches en hydrates de carbone ; deux espèces de reboisement (Gmelina et Eucalyptus) ; et un mélange de feuillus français servant de référence.On observe que les bois tropicaux donnent un peu plus de charbon de bois et un peu moins de produits pyroligneux que les bois des zones tempérées. En outre, les produits obtenus semblent liés à la composition chimique du bois ; une teneur élevée en lignine se traduit par un rendement plus élevé en charbon de bois, un pourcentage élevé de pentosanes donne plus d'acide acétique et d'acétates, et une teneur élevée en cellulose donne plus de méthanol. En outre, les bois contenant de grandes quantités d'extraits d'alcool et de benzène peuvent provoquer des dépôts goudronneux dans les circuits.D'un point de vue pratique, il semble que l'on puisse envisager, sans trop de risques, de remplacer les bois durs de la zone tempérée par des essences tropicales pour alimenter une filière industrielle de charbon de bois.
Maternal Reason for Choosing Caesarean Section at Won Request and Without Medical Indication : A Literature Review
Authors: Cipta Wardhani Gusna Pricilia , Pudji Lestari
Published: November 2024

New research from the World Health Organization (WHO) shows that the incidence of caesarean sections in childbirth continues to increase globally, accounting for more than 1 in 5 (21%) of all births. Although there is a considerable amount of literature on complications following caesarean section, the demand for caesarean section without medical indication and at maternal request is increasing. This study aimed to identify the reasons why mothers choose to have a caesarean section without a medical indication. Mothers may choose to have a caesarean section due to fear of vaginal delivery, concerns about perceived health risks, previous traumatic childbirth experiences, worries about future sexual life, positive attitudes towards the caesarean section, and the decision-making process. It can be concluded that many expectant mothers are not adequately prepared for this process. Tackling this problem requires collaboration between different stakeholders. WHO has recommended guidelines for non-clinical interventions to reduce unnecessary caesarean sections, targeting women, health professionals and health organizations, facilities, or systems.
Characteristics and Management of Laryngopharyngeal Reflux in The Elderly : A Case Report
Authors: Ikhsan Wahyu , Hidayati Aliyah
Published: November 2024

Laryngopharyngeal reflux is a condition resulting from the retrograde flow of stomach acid through the distal esophagus into the laryngopharyngeal area. The prevalence of laryngo-pharyngeal reflux in the elderly population remains uncertain.  Therefore, the symptoms, findings, and therapy for laryngopharyngeal reflux in the elderly require further investigation. To analyze the characteristics and management of laryngopharyngeal reflux in the elderly. A case of laryngopharyngeal reflux in a 70-year-old woman who frequently experiences sudden choking sensations is presented in this report.  Other symptoms include hoarseness, a sensation of throat obstruction, and chest burning. We explored literature on laryngopharyngeal reflux in the elderly through PubMed, PMC, and Google Scholar databases to discuss the case. Laryngopharyngeal reflux in the elderly has a lower reflux symptoms index but a higher reflux finding score. Mental health factors significantly influence laryngopharyngeal reflux incidence in the elderly. Therefore, besides pharmaco-logical therapy, additional non-pharmacological therapies need to be considered to ensure effective laryngopharyngeal reflux treatment. Elderly patients diagnosed with laryngopharyngeal reflux have different presentations and management of the disease compared with younger patients.
Study of Bacteriological Content and Risk Factors of Drinking Water Consumption Patterns in Cases of Stunting Toddler
Authors: Ahmad Zaerozi  , Joko Tri , Nurjazuli
Published: November 2024

Stunting is one of global nutrition problems, especially in developing countries including Indonesia. The prevalence of stunting in Demak Regency, Indonesia, in 2021 was 4.34%, and in 2022 it was 2.99%. However, stunting problem remains a priority because the impact of stunting can hinder efforts to enhance the health of the society and the development of the quality of human resources. Risk factors for stunting are influenced by behavioral aspects of the environment, like sanitation and drinking water. This study aimed to determine the content of bacteriological factors that contribute to the risk pattern of drinking water consumption in cases of stunting toddlers in Temuroso Village, Working Area of Guntur I Health Center, Demak Regency, Indonesia. This study was a quantitative observational case study. The population included families and toddlers in Temuroso Village, totaling as many as 854 people. The sampling technique was purposive sampling, so the sample size was 182 people for cases and controls. Data analysis used Chi-Square test and linear regression test. The bacteriological content was predominantly negative (66.5%), with the majority of subjects showing no infections (67%). Most participants fell into the high drinking water consumption category (62.1%). Stunting incidence was significantly associated with bacteriological content (p <0.0001) and drinking water consumption patterns (p <0.0001). Among these, bacteriological content was the most dominant factor influencing stunting (exp B =0.199). In summary, the primary risk factors for stunting among toddlers in Temuroso Village, within the Guntur I Health Center working area, Demak Regency, were bacteriological content (p <0.000) and drinking water consumption patterns (p <0.000).
Characteristics of Hearing Impairment in Patients with Suspected Congenital Rubella Syndrome at the ENT Clinic of Prof. Dr. I.G.N.G Ngoerah Hospital Denpasar, Indonesia
Authors: Raditya I Gede Wahyu Adi , I Made Wiranadha
Published: November 2024

Asymptomatic rubella virus infection can cause delays in the diagnosis of rubella in pregnant women, leading to the development of congenital rubella syndrome (CRS). The clinical manifestations of congenital rubella syndrome are called the rubella triad, which includes heart problems, eye problems, and hearing disorders. Sensorineural hearing loss is the most common type of hearing loss in children with rubella infection. This study aimed to determine the characteristics of hearing loss in CRS patients. This study used a retrospective descriptive research design, utilizing secondary data from the medical records of patients with CRS who underwent hearing examinations at the Ear, Nose, Throat (ENT) Polyclinic of Prof. dr. I.G.N.G. Ngoerah Hospital Denpasar, Indonesia. The study found that the most common age group among suspected CRS patients was 6 - 12 months (51.42%), the majority of these patients were male (62.86%), the most frequent clinical signs and symptoms in suspected CRS patients were congenital heart disease (CHD) as a major criterion (60%), and microcephaly as a minor criterion (77.14%). Based on the CRS case criteria, none of the suspected CRS patients were diagnosed with confirmed CRS, with most cases being classified as clinical CRS (65.71%). The hearing loss in suspected CRS patients was entirely sensorineural type with the majority of cases being bilaterally and to a very severe degree (53.57%)
Renal Cell Carcinoma with Thyroid and Bilateral Adrenal Gland Metastases
Authors: Badak Bartu , Kısalar İbrahim , Yılmaz Arda Şakir , Yaldir Emel
Published: November 2024

Renal cell carcinoma is the most common type of malignant kidney disease, representing more than 90% of cases. It frequently metastasizes to the lungs, bones, liver and brain. Thyroid and adrenal metastases are rare. In this case report, we present a 64-year-old man with renal cell carcinoma who developed bilateral adrenal metastases three years after right radical nephrectomy and thyroid metastases five years later. Renal cell carcinoma has a high metastasis rate and requires careful follow-up. The increasing use of non-invasive imaging modalities has increased the detection rates of rare adrenal and thyroid metastases. Due to the rarity of such cases, standard treatment protocols are not well defined, emphasizing the need for careful follow-up even years after surgery.
Impact of training system, soil management and soil water holding capacity on vine water status in a changing climate over 60 years in the Cognac production area
Authors: Zito Sebastien , Van Leeuwen Cornelis , Bois Benjamin
Published: November 2024

This study investigates the impact of vine training systems on water deficits in the Cognac region (France), through the application of a vine water balance model, taking into account different soil water holding capacities (SWHC) and soil management strategies, including grass cover. Using climate data from the SAFRAN gridded database, over 2 million simulations were performed for the period 1962 to 2021 to quantify the response of grapevine water status under varying training systems and environmental conditions. Indices based on simulated relative stomatal conductance were developed to characterise the intensity of grapevine water deficit during the critical flowering-to-maturity period.
Results show a significant trend of increasing water deficit between 1962 and 2021, particularly in the north-western part of the region, affecting 23 % of the Cognac production area. Sensitivity analysis of the water balance model indicates that SWHC is the predominant factor influencing grapevine water status, explaining nearly 80 % of the variance in water deficit days. The simulations further suggest that adjustments in canopy width and grass cover have a significant effect on the duration and severity of water deficit.
The methodology developed in this research allows quantifying the relative importance of major drivers of vine water deficits: SWHC, training system parameters and vineyard floor management, under different climatic conditions. It can be used as a basis for providing easy-to-implement vineyard management strategies to mitigate the effects of climate change in viticulture. It was applied to the Cognac region, but the workflow developed is applicable to any grape-growing region in the world.
Decoupling Abundance and Timing of Presence to Characterize Distributional Patterns of Longfin Smelt (Spirinchus thaleichthys) in the San Francisco Estuary
Authors: Tobias Vanessa , Baxter Randall
Published: November 2024

Coincident changes in abundance and behavior pose a challenge for interpreting abundance indices derived from monitoring programs. In the San Francisco Estuary, long-term monitoring programs have documented changes in overall Longfin Smelt (Spirinchus thaleichthys) abundance as well as regional differences in presence over time. Seasonal patterns in regional presence of Longfin Smelt through its life cycle were developed using monitoring data and generalized additive modelling. We investigated the year-to-year variability in seasonal patterns of presence using functional data analysis to separate variability due to population size from variability due to changing timing of presence. We found that Longfin Smelt have consistent seasonal distribution and that two trawl types were needed to accurately describe those patterns. After accounting for variability due to population abundance, shifts in the timing of presence were evident in three regions. These shifts were interpreted as changes in migration timing. The most variable period for the upstream regions was for age-0 fish in summer and for the downstream region was for age-0 fish in late fall. This study highlights that identifying portions of the life cycle with the most and least variability in distribution can help inform the types of management strategies that will be most effective. It also illustrates an analytical method that can be used to address the problem of confounded effects of abundance and behavior on patterns in monitoring data.
Towards a Better Diagnosis and Treatment of Dementia: Identifying Common and Distinct Neuropathological Mechanisms in Alzheimer’s Disease and Vascular Dementia
Authors: Vollhardt Alisa , Frölich Lutz , Stockbauer Anna Christina , Danek Adrian , Schmitz Christoph , Wahl Anna-Sophia
Published: November 2024

Alzheimer’s disease (AD) and vascular dementia (VaD) together contribute to almost 90% of all dementia cases leading to major health challenges of our time with a substantial global socioeconomic burden. While in AD, the improved understanding of Amyloid beta (Aß) mismetabolism and tau hyperphosphorylation as pathophysiological hallmarks has led to significant clinical breakthroughs, similar advances in VaD are lacking. After comparing the clinical presentation, including risk factors, disease patterns, course of diseases and further diagnostic parameters for both forms of dementia, we highlight the importance of shared pathomechanisms found in AD and VaD: Endothelial damage, blood brain barrier (BBB) breakdown and hypoperfusion inducing oxidative stress and inflammation and thus trophic uncoupling in the neurovascular unit. A dysfunctional endothelium and BBB lead to the accumulation of neurotoxic molecules and Aß through impaired clearance, which in turn leads to neurodegeneration. In this context we discuss possible neuropathological parameters, which might serve as biomarkers and thus improve diagnostic accuracy or reveal targets for novel therapeutic strategies for both forms of dementia.
Comparing the Relative Efficacy of Generalized Estimating Equations, Latent Growth Curve Modeling, and Area Under the Curve with a Repeated Measures Discrete Ordinal Outcome Variable
Authors: Rodriguez Daniel , Verma Ryan , Upchurch Juliana
Published: November 2024

Researchers are often interested in the effects of change in one variable on change in a second variable, requiring the repeated measures of two variables. There are several multivariate statistical methods appropriate for this research design, including generalized estimating equations (GEE) and latent growth curve modeling (LGCM). Both methods allow for variables that are not continuous in measurement level and not normally distributed. More recently, researchers have begun to employ area under the curve (AUC) as a potential alternative when the nature of change is less important than the overall effect of time on repeated measures of a random variable. The research showed that AUC is an acceptable alternative to LGCM with repeated measures of a continuous and a zero-inflated Poisson random variable. However, less is known about its performance relative to GEE and LGCM when the repeated measures are ordinal random variables. Further, no study to our knowledge has compared AUC to LGCM or GEE when there are two longitudinal processes. We thus compared AUC to LGCM and GEE, assessing the effects of repeated measures of psychological distress on repeated measures of smoking. Results suggest AUC performed equally well to both methods, although missing data management is an issue with both AUC and GEE.
What to Expect from Brazil as a Nation Certified as Free from Foot-and-Mouth Disease (FMD) without Vaccination
Authors: Salvarani Felipe Masiero , Lins André De Medeiros Costa , dos Santos Janayna Barroso , Martins Fernanda Monik Silva
Published: November 2024

Achieving Foot-and-Mouth Disease (FMD)-free status without vaccination marks a significant milestone for Brazil, a major agricultural powerhouse with extensive cattle herds and vast borders. This certification represents not only a scientific and logistical achievement but also an oppor-tunity for enhanced market access and strengthened biosecurity. However, transitioning to this status involves challenges, including maintaining stringent monitoring and surveillance, man-aging porous border regions, and mitigating risks from neighboring regions with varying FMD statuses. This review explores the expectations surrounding Brazil’s new status, including antic-ipated economic benefits, the influence on Brazil’s international trade position, and the role of sustainable disease management practices. We also discuss potential risks, such as accidental re-introduction and surveillance gaps, which could impact livestock health and trade dynamics. With a focus on effective biosecurity, regional cooperation, and advanced diagnostic capabilities, Bra-zil’s journey to maintaining FMD-free status highlights both the opportunities and complexities of disease control in a nation deeply reliant on its agricultural sector. This status demands ongoing surveillance to support Brazil’s agricultural economy and ensure long-term health security for its livestock industries.
Novel Visualization of Building Earthquake Response Recorded by a Dense Network of Sensors
Authors: Cruz Lichiel , Todorovska Maria I , Trifunac Mihailo D , Aihemaiti Alimu , Lin Guoliang , Cui Jianwen
Published: November 2024

Strong motion records from full-scale structures provide the ultimate evidence of how real structures, in situ, respond to earthquakes. The most effective method for visualizing the recorded response is by animation. This paper presents a novel method for visualization of the motion of a building that is densely instrumented with triaxial accelerometers and rotational seismometers. The method is based on one- and two-dimensional biharmonic spline interpolation of the motion between multiple sensors on a floor or along the building height. It is demonstrated on a 50-story skyscraper uniquely instrumented with multiple triaxial accelerometers per floor, approximately at every five floors above ground and at two basement levels, and two borehole arrays measuring the motion of the soil very near the building foundation. The animations provide valuable insight into the three-dimensional structural response, including wave propagation through the structure and the interplay between translations and rotations, which will be useful for testing existing and developing new methods for structural health monitoring of buildings and for the further development of building design codes. Animations of selected earthquakes can be found on YouTube at @TPYC-seismic.
Biodegradable Stents in the Treatment of Arterial Stenosis
Authors: Dinc Rasit , Ekingen Evren
Published: November 2024

Arterial diseases (AD) are a major health problem with high mortality and morbidity. Endovascular interventions, including balloon angioplasty (BA), bare-metal stent (BMS), drug-eluting stents (DES) and drug-coated balloons (DCB), have provided significant progress in their treatments. However, the problem has not been fully solved, particularly restenosis remains a major issue. In this context, bioresorbable vascular stents (BVSs) have been a promising investigation topic. The articles that evaluate BVSs were included in this traditional review manuscript. Studies have shown that challenges remain, such as negative vascular remodeling and elastic recoil after angioplasty, stent-related injury and in-stent restenosis after BMS. Although DESs have reduced these problems to an important extent, the durable stent structures cannot prevent late stent thrombosis, and delay arterial recovery. BVSs have lower support strength and tend to have thicker scaffold, increasing the risk of scaffold thrombosis.
Although the study results are inconsistent, the superiority of BVS over DES has not been demonstrated in randomized trials, and DES devices are still the first choice for most arterial disease cases. Esprit BTK (Abbott Vascular) was approved by the US FDA for use in below-knee lesions in 2024, which may be a promising light for the use of BVS in other vascular events. Improving the scaffold design and thickness of BVSs may offer a new pathway. Large-scale and longer-follow-up comparative studies are still needed.
The article aims to provide an overview of the use of biodegradable stents in the endovascular treatment of vascular stenosis.