bluuebunny/crossref_metadata_2025 huggingface dataset:
INTELIGÊNCIA ARTIFICIAL E DIREITO: UMA ANÁLISE DO SINAPSES – IA DO TRIBUNAL DE JUSTIÇA DO ESTADO DE RONDÔNIA (TJRO)
Authors: Alexandrino de Souza Gomes Natascha , Rodrigues Novo Jose Raniel , Lima Nascimento Luciano
Published: December 2024

O uso da Inteligência Artificial (IA) no direito brasileiro já é uma realidade e a tendência é de se expandir cada vez mais; contudo, não sem riscos ao devido processo legal, bem como aos direitos e garantias fundamentais. Assim, o presente artigo tem como objeto avaliar o impacto do sistema Sinapses, IA desenvolvida pelo Tribunal de Justiça do estado de Rondônia (que é o modelo brasileiro de IA, para o Conselho Nacional de Justiça), e suas implicações nos direitos fundamentais, na transparência e normas éticas. Para tanto, o estudo se vale da metodologia de pesquisa documental, revisão bibliográfica e análise dos dados quali-quantitativamente, bem como utilizando o método dedutivo. Segundo CNJ (2023), a última pesquisa mapeou 111 projetos de Inteligência Artificial desenvolvidos por 53 tribunais. Como resultado, a pesquisa evidencia que o Sistema Sinapses tem a finalidade de nacionalizar os modelos já desenvolvidos nas diversas esferas judiciais e, com isso, a justificativa de sua criação é aprimorar os serviços prestados pelo Judiciário brasileiro. Todavia, não podemos perder de vista que a celeridade processual, apesar de relevante, não pode desconsiderar o devido processo legal, os direitos e garantias fundamentais. Além disso, o TJRO deve garantir o respeito pelas regras relativas à proteção de dados pessoais e normas éticas correlatas. Ademais, destaca-se a falta de transparência do Poder Judiciário nessa implementação.
Fluctuation Induced Force in the Nagle-Kardar Model in Ensemble with Conserved Magnetization
Authors: Dantchev Daniel , Tonchev Nicholay S. , Rudnick Joseph
Published: December 2024

Since for finite systems the thermodynamic potentials are not equivalent the fluctuation induced forces defined in any of them lead to different forces - Casimir force (CF) in grand canonical ensemble (GCE) and Helmholtz force (HF) in canonical (CE) one with fixed magnetization. Here we consider the HF within Nagle-Kardar model with periodic boundary conditions. Thus, the current study is complimentary to the recent one for the CF, see , in the same model. We remind that the model represents one-dimensional Ising chain with long-range equivalent-neighbor ferromagnetic interactions of strength Jl/N>0 superimposed on the nearest-neighbor interactions of strength Js which could be either ferromagnetic (Js>0) or antiferromagnetic (Js<0). In the infinite system limit the model exhibits in the plane (Ks=βJs,Kl=βJl) a critical line 2Kl=exp−2Ks,Ks>−ln(3)/4, which ends at a tricritical point (Kl=−3/2,Ks=−ln(3)/4). The obtained results demonstrate that the temperature behavior of the HF differs essentially form the one of the CF. Furthermore, we show that the CE and GCE are not equivalent for the current model - even in the thermodynamic limit. Finally, in the phase space {Ks,Kl,m} we determine the regions of stable states of the system.
THE EFFECT OF MOBILIZATION ON THE INCIDENCE OF FLATULENCE IN POST SECTIO CAESAREA PATIENTS
Authors: Suhartini Leni , Pardede Tiarma Uli , Rahmatika Cintya Putri , Widyastuti Sri
Published: December 2024

Background: Sectio Caesarea (SC) surgery causes anxiety, postoperative pain, and feelings of fear, which causes late mobilization, resulting in complaints of flatulence.

Objectives: To find out more about the effect of mobilization on the incidence of flatulence in post section caesarea patients.

Method: This study used observational analytical studies, cross-sectional design, mothers who gave birth in January-February 2024, a population of 67 people; samples were taken by purposive sampling; mothers giving birth by SC (cito and elective). A sample of 55 respondents was obtained (SC ERACS 12 respondents, and non-ERACS 43 respondents).

Result: The results found that there were as many as 13 respondents (81.3%) who experienced flatulence due to late mobilization. While in mothers who mobilized early, there was only 1 respondent (2.6%) who experienced flatulence. The results of statistical tests obtained a p value of 0.000, and it can be concluded that there is a difference in the proportion of flatulence of SC postoperative patients in mothers who do late mobilization and early mobilization (there is a significant effectiveness between mobilization and flatulence of SC postoperative patients). From the results of the analysis, the value of OR = 0.006 was also obtained, meaning that mothers who mobilize late have a 1 chance of experiencing postoperative flatulence compared to mothers who mobilize early.

Conclusion: Early mobilization can reduce flatulence complaints in post-SC patients. Increasing education about the importance of postoperative mobilization to recover faster and avoid other complications that can arise due to postoperative SC, create interesting educational media to increase maternal knowledge. 
EFFECTS OF FAMILY SMOKING HABITS ON BRONCHOPNEUMONIA INCIDENCE AMONG TODDLERS
Authors: Iqbal S Muhammad , Oktaviyana Cut , Ajali Darman
Published: December 2024

Background: Bronchopneumonia, one of the variants of pneumonia that commonly affects the bronchi and alveoli, especially in toddlers, is often caused by exposure to cigarette smoke in the surrounding environment. In 2019, there were 2,157 cases of bronchopneumonia in toddlers in Aceh Province. The presence of family members who smoke increases the risk of bronchopneumonia in toddlers because cigarette smoke can disrupt lung defense mechanisms. This research aims to determine the influence of family members' smoking behavior on the incidence of bronchopneumonia in toddlers in the pediatric ward of RSUD dr. H. Yuliddin Away Tapaktuan, South Aceh.

Methods: This research design is quantitative with a cross-sectional study approach. The study population consisted of 71 toddlers, with 41 respondents selected as samples using purposive sampling technique. The study was conducted from February 7 to 15, 2024, using interview instruments and examination sheets to assess bronchopneumonia criteria. Data analysis was performed using the chi-square test.

Results: The research findings indicate that the average family members of toddlers who smoked the most were the toddlers' parents, with a percentage of 56%, and smoking habits indoors reached 68.3%, while the proximity of smokers to toddlers reached 90.2%. The chi-square test analysis showed the influence of family members' smoking behavior on the incidence of bronchopneumonia in toddlers, with a p-value of 0.007 (< α = 0.05).

Conclusion: The smoking behavior of family members can cause respiratory disorders in toddlers and thus increasing the risk of bronchopneumonia
QUALITY OF EXPERIENCE BERMAIN COLOR GUARD DI MARCHING BAND LA TANSA CORPS
Authors: Rahmat Suryo Samudro
Published: December 2024

The color guard requires body coordination, concentration, and mastery of equipment. Color guard performances are not just shown off, but are presented in the context of competition. Color guard players often feel adrenaline during the performance, but how performer manage this case through their experience. The quality of this symptom is analyzed using a scalpel from Jackson and Mihaly's perspective regarding the flow experience when playing color guard, especially the differences that appear during pre-performance and during the performance. So that the research does not spread in all directions, the researcher more specifically discusses research on the performance of the color guard in the La Tansa Coprs Marching Band at the 2023 Grand Prix Junior Band Championship and seek 2 performances before, which are 2017 Grand Prix Junior Band Championship and 2017 Grand Prix Marching Band Championship. The researcher uses direct observation to see the reality of what happened and explains it descriptively. The results of the research found that the quality of the La Tansa Corps Marching Band color guard players was able to create a great connection with the spectators through the performers' subjective experiences.
Model Penyajian Tari Ronggeng Beken dalam Festival Pesona Nusantara Bekasi Keren dalam Perspektif Performativity menurut Richard Schechner
Authors: Rizki Ramadhani Anjani Ayu , Nursilah  , B. Kristiono Soewardjo
Published: December 2024

Tari Ronggeng Beken merupakan sebuah ekspresi budaya masyarakat Kota Bekasi yang ditampilkan dalam Festival Pesona Nusantara Bekasi Keren. Artikel ini membahas model penyajian Tari Ronggeng Beken melalui perspektif performativity menurut Richard Schechner, yang mencakup elemen ritual, restored behavior, dan performativity dalam pertunjukan tersebut. Melalui pendekatan kualitatif dengan metode etnografi, penelitian ini menganalisis bagaimana Tari Ronggeng Beken mencerminkan identitas budaya lokal sekaligus beradaptasi dengan dinamika masyarakat multikultural di Bekasi. Tari Ronggeng Beken, yang disusun oleh Gema Nusa Patriot, memadukan unsur budaya Betawi dan Sunda dalam gerak dan iringan musiknya, serta menyimbolkan keunikan kultural Bekasi. Penyajian tari ini juga mengintegrasikan properti modern seperti kacamata hitam, menambah dimensi "keren" atau modern dalam tradisi lokal. Hasil penelitian menunjukkan bahwa pertunjukan ini tidak hanya sebagai hiburan, tetapi juga sebagai media penguatan identitas budaya masyarakat Bekasi dalam festival berskala besar. Perspektif performativity Schechner membantu memahami dinamika penyajian Tari Ronggeng Beken, yang menciptakan ruang bagi transformasi sosial dan budaya di tengah masyarakat multikultural.
Numerical modeling of supercritical flow in the Los Angeles River : part II : existing conditions Adaptive Hydraulics numerical model study
Authors: McAlpin Tate , Petrie John , Savant Gaurav , Savant Daniel , Hogan Angela , Brown Gary
Published: December 2024

The Los Angeles District of the US Army Corps of Engineers is assisting the City of Los Angeles with restoration efforts on the Los Angeles River. The city wishes to restore portions of the channelized river to a more natural state with riparian green spaces for both wildlife and public recreation usage. The Los Angeles River provides an important role from a flood-control perspective, and functionality needs to be preserved when contemplating system modifications. This report details the development of an Adaptive Hydraulics numerical model capable of modeling this complex system consisting of both subcritical and supercritical flow regimes. The model geometry was developed to represent the existing conditions system for future usage in quantifying the impact associated with proposed restoration alternatives. Due to limited hydraulic data in the study area, an extensive model validation to observed data was not possible. A model was developed and simulated using the most appropriate input parameters. Given the lack of measured data for model validation, an extensive number of sensitivity simulations were completed to identify the most impactful parameters and quantify a reasonable level of confidence in the model results based on the uncertainty in the model inputs.
Macrolophus pygmaeus (Heteroptera: Miridae) induces systemic resistance in tomato against Meloidogyne spp
Authors: Expósito Alejandro , Urbaneja-Bernat Pablo , Boncompte Sara , Fullana Aida Magdalena , Giné Ariadna , Sorribas Francisco Javier , Riudavets Jordi
Published: December 2024

The ability of Macrolophus pygmaeus to induce systemic resistance in susceptible and Mi1.2 resistant tomato against Meloidogyne spp. was evaluated in pot experiments. The susceptible cv. Roma and the resistant cv. Caramba were exposed to 15 M. pygmaeus nymphs per plant in mesh bags for 48h and then were inoculated with 1 second-stage juvenile (J2) of M. incognita or 3 J2 cm− 3 of soil of a mixed community of M. arenaria, M. hapla, and M. javanica. Tomato plants were maintained in a growth chamber during 40 days. Then the number of egg masses and eggs per plant were determined. In addition, the preference of the insect was estimated confronting nematode-infected vs. non-infected plants in a Y-tube olfactometer and in insect cages, where 10 females were released into each cage containing resistant or susceptible tomato plants. After 1, 2, 4, 24, 48 and 72h, the number of M. pygmaeus was counted as well as the offspring after 14 days. M. pygmaeus reduced the infectivity and reproduction by 37% and 53%, in the susceptible tomato inoculated with M. incognita and by 52% and 37% when inoculated with the nematode community but no effect was observed in the Mi1.2 resistant tomato irrespective of the nematode inoculum. The preference and the offspring of M. pygmaeus was not negatively affected by the nematode infection or the tomato cultivar. In conclusion, pre-induction of tomato plants with M. pygmaeus reduces RKN infectivity and reproduction in susceptible but not in Mi1.2 resistant tomato.
Photoelectrochemical iron(III)-catalysis for late-stage C–H fluoroalkylations
Authors: Ackermann Lutz , Motornov Vladimir , Trienes Sven , Resta Simonetta , Oliveira João C. A. , Lin Zhipeng , Liu Zhi , von Münchow Tristan
Published: December 2024

Chemo- and site-selective functionalization of complex molecules poses a fundamental challenge. In this regard, the synergetic combination of photoexcitation with electron transfer by anodic oxidation bears unique potential for novel reaction manifolds that go beyond individual photo- or electrochemistry.1–3 Herein, we introduce a resource-economic photoelectrocatalysis strategy to enable versatile direct fluoroalkylations catalyzed by Earth-abundant iron and paired with the hydrogen evolution reaction (HER). Notably, the devised approach proved amenable to versatile late-stage C–H fluoroalkylations of bio-relevant heterocycles, such as xanthines, nucleobases, and nucleosides. Mechanistic studies supported a ligand-to-metal charge transfer-induced formation of the fluoroalkyl radical.
Porous Threaded Titanium Implant Screws have Higher Insertional Torque Compared to Standard Screws
Authors: Collins Andrew , Wallace Stephen , DeKeyser Graham , Polly David , Firoozabadi Reza
Published: December 2024

Purpose Posterior pelvic ring screw back out and loss of fixation may result from poor screw purchase, prevalent in geriatric pelvic ring injuries where the cancellous bone is often osteoporotic. To reduce screw back out, there has been increasing use of porous threaded titanium implant (PTTI) screws for posterior pelvic fixation rather than standard cannulated, buttress threaded screws. This study aims to assess the insertional torque of helical PTTI screws compared to standard cannulated screws as there is limited evidence regarding the biomechanical fixation profiles among screws.Methods Fifteen orthopaedic trauma surgeons inserted screws into a validated surrogate for osteoporotic cancellous bone. Insertional torque was measured during screw placement in three separate scenarios for each surgeon: (1) placement of a standard 7.3-millimeter (mm) screw into a new bone model, (2) placement of a PTTI screw into a new bone model, and (3) placement of a PTTI screw over a previously placed 7.3mm screw hole from which it was removed (rescue screw). The insertional torque was calculated across all surgeons and analyses were conducted comparing scenarios (1) and (2), and (1) and (3).Results The average insertional torque of 7.3mm screws was 0.358 ± 0.223 Nm and the maximum insertional torque was 0.627 ± 0.365 Nm. The average insertional torque for the PTTI screws was 0.929 ± 0.551 Nm, 2.59 times more than that of the 7.3mm screw (p < 0.001) while the maximum insertional torque was 1.877 ± 0.671 Nm, 2.99 times that of the standard screw (p < 0.001). When placed into the prior 7.3mm screw hole (rescue), the PTTI screws generated an average insertional torque of 0.711 ± 0.405, still 1.99 times greater than that of the 7.3mm screw (p < 0.001), and maximum torque of 1.607 ± 0.427 Nm, 2.56 times greater than the standard screw (p < 0.001).Conclusion Significantly greater maximum and average insertional torque were generated with the PTTI screws compared to the standard screws, even when used as a rescue screw in cancellous bone models. Further studies assessing clinical outcomes and failure rates with PTTI screws will better define their clinical utility.
Baseline Cardiovascular and Oximetric Parameters Across the Lifespan of Male Sprague Dawley Rats
Authors: Nugent William H. , Golub Aleksander S. , Pittman Roland N. , Song Bjorn K.
Published: December 2024

Human populations are experiencing unprecedented growth and longevity creating an urgent need for research into the pathologies, mechanisms, and dysfunctions of senescence. Invasive measurements and long-term control conditions for longitudinal studies are infeasible in humans, necessitating surrogate animal models. Rats have short lifespans (2–3 years) with translatable cardiovascular systems, and Sprague Dawley microcirculatory preparations are key to studying the oxygen transport mechanisms critical to aging. Here we present baseline physiological data of 61 male, Sprague Dawley rats at 3, 6, 12, 18, and 24 months of age. Anesthetized animals were surgically prepared for femoral arterial and venous cannulations, tracheal intubation, and exteriorization of the spinotrapezius muscle. Measurements included cardiovascular function, blood gases, and peripheral tissue interstitial oxygen tension (PISFO2) using phosphorescence quenching microscopy. Intrinsic heart rates decreased with age without significant changes to blood pressure. Arterial oxygen tension declined 17% by 18 and 24 Months (p < 0.05) while pACO2 and PISFO2 were unchanged. Lactate was elevated at 12 and 18 Months along with an alkaline shift in blood pH. Heart rate and the decline in pAO2 without a rise in pACO2 are conserved phenomena in human aging. The continuity of resting PISFO2 despite an anaerobic shift in metabolism may be due to declining mitochondrial function and dysregulation of the vascular response to hypoxemia, which are also present in aged humans. These findings contribute to our understanding of age-related physiological changes and underscore the suitability of the Sprague Dawley rat model for aging research.
Gene co-expression poorly reflects expert-curated transcription factor-target gene regulation
Authors: Sarkar Suryadipto , Blumenthal David B.
Published: December 2024

Gene co-expression networks (GCNs) are networks with genes as nodes and edges that indicate correlation between two genes' expression profiles across several samples. Since GCNs are conceptually simply and straightforward to compute from gene expression data, they are often used as proxies for gene regulatory networks (GRNs) whose edges encode transcriptional regulation between transcription factor (TFs) and their target genes. However, many other mechanisms besides direct transcriptional regulation can lead to correlated expression profiles, including joint co-regulation and stoichiometry underlying protein-protein interactions (PPIs). We hence asked the simple question if GCNs are indeed good proxies for GRNs, and addressed it by comparing GCNs inferred from 15 healthy tissue and 15 corresponding cancer gene expression datasets to a state-of-the-art expert-curated GRN, a co-regulation network derived from the expert-curated GRN, as well as a widely used PPI network. Our results indicate that GCNs mostly reflect PPIs and joint co-regulation, casting doubt on the usage of gene co-expression as a proxy for direct transcriptional regulation.
Long-read epigenomic diagnosis and prognosis of Acute Myeloid Leukemia
Authors: Marchi Francisco , Landwehr Marieke , Schade Ann-Kathrin , Shastri Vivek , Ghavami Matin , Sckaff Fernando , Marrero Richard , Nguyen Nam , Mansinghka Vikash , Cao Xueyuan , Slayton William , Starostik Petr , Ribeiro Raul , Rubnitz Jeffrey , Klco Jeffery , Gamis Alan , Triche Timothy , Ries Rhonda , Kolb Edwards Anders , Aplenc Richard , Alonzo Todd , Pounds Stanley , Meshinchi Soheil , Cogle Christopher , Elsayed Abdelrahman , Lamba Jatinder
Published: December 2024

Acute Myeloid Leukemia (AML) is an aggressive cancer with dismal outcomes, vast subtype heterogeneity, and suboptimal risk stratification. In this study, we harmonized DNA methylation data from 3,314 patients across 11 cohorts to develop the Acute Leukemia Methylome Atlas (ALMA) of diagnostic relevance that predicted 27 WHO 2022 acute leukemia subtypes with an overall accuracy of 96.3% in discovery and 90.1% in validation cohorts. Specifically, for AML, we also developed AML Epigenomic Risk, a prognostic classifier of overall survival (OS) (HR=4.40; 95% CI=3.45–5.61; P<0.0001), and a targeted 38CpG AML signature using a stepwise EWAS-CoxPH-LASSO model predictive of OS (HR=3.84; 95% CI=3.01–4.91; P<0.0001). Finally, we developed a specimen-to-result protocol for simultaneous whole-genome and epigenome sequencing that accurately predicted diagnoses and prognoses from twelve prospectively collected patient samples using long-read sequencing. Our study unveils a new paradigm in acute leukemia management by leveraging DNA methylation for diagnostic and prognostic applications.
The cylindrical devices with tunable positive, infinite, and negative capacitance for dynamic random access memory
Authors: Hwang Cheol Seong , Park Hyeon Woo , Koo Won-Tae , Suh Dong Ik , Byun Seungyong , Kim Youngmo , Kim Ja-Yong , Ryu Seung Wook , Jeon Heeyoung , Im Ki Vin , Lee Gwangyeob , Youn Taeone , Yi Jaeyun , Lee Seho , Cha Seon Yong
Published: December 2024

The capacitance behavior of the ultra-thin ferroelectric/dielectric (FE/DE) stacked devices in the nanoscale cylindrical structure deviated from the negative capacitance (NC) state to unpredicted other states. This work confirmed that the ultra-thin (2.0–3.0 nm) FE Hf0.33Zr0.67O2 layer could have a positive capacitance, infinite capacitance, or NC by controlling the thickness of the stacked DE Al2O3 layer thickness (1.0–3.0 nm). Detailed analytical model and numerical simulation based on phase-field modeling, considering the FE polarization bound charge compensation by the injected/trapped interfacial carriers and the geometry effect of the cylinder, precisely identified the change of the inhomogeneous stray field energy, which played a crucial role in determining the capacitance state. Further analysis of the models revealed that the capacitance variation is strongly correlated to the extent of the initial polarization charge compensation of the ferroelectric domains. This work provides guidelines for developing the next-generation capacitors in dynamic random access memory.
Unique structural features in a deep-sea CYP51 relate to high pressure adaptation
Authors: Lepesheva Galina , Hargrove Tatiana , Lamb David , Wawrzak Zdzislaw , Minasov George , Goldstone Jared , Kelly Steven , Stegeman John
Published: December 2024

Cytochromes P450 (CYP) form one of the largest enzyme superfamilies on Earth, with similar structural fold but biological functions varying from synthesis of physiologically essential compounds to metabolism of myriad xenobiotics. Here we determined the crystal structures of Coryphaenoides armatus and human sterol 14α-demethylases (CYP51s). Both structures reveal elements that imply elevated conformational flexibility, uncovering molecular basis for faster catalytic rates, lower substrate selectivity, and resistance to inhibition. These elements as well as the unique inward/outward location of the FG arm/β4 hairpin in the fish CYP51 structure were not predicted by artificial intelligence molecular modelling. The structural distinction of C. armatus CYP51, which is the first structurally characterized deep-sea P450, suggests stronger involvement of the membrane environment in regulation of this enzyme function. We interpret this as a co-adaptation of membrane protein structure with changes in membrane lipid composition during evolutionary incursion to life in the deep sea.
Creative Industry in Strategic Economic Priorities
Authors: Alimuradov Murad , Midov Aslan
Published: December 2024

The creative industry is becoming a key factor in strategic development. The article describes strategic opportunities and threats for creative industry businesses across Russia, as well as their impact on economic growth. The author used the method of statistical analysis to examine the export of creative goods and services and assess the impact of the COVID-19 pandemic on the creative sector. The research relied on the theory of strategy and the methodology of strategizing developed by Professor Vladimir L. Kvint. The USA and China are leaders in the export of creative goods. Russia demonstrates very slow growth, which is associated with external shocks and sanctions. The current strategic trends include export structure diversification and IT sector growth. To gain competitive advantage, domestic creative businesses need state support for human capital and project development, e.g., technology transfer centers, startup support, etc.
Key Elements of Technological Independence Strategy in Russian Mechanical Engineering
Authors: Krayushkina Valeriya , Varenik Maria
Published: December 2024

The article describes the strategizing prospects for Russia’s technological sovereignty in the sphere of mechanical engineering. The authors used the methodology of strategizing developed by Professor V. L. Kvint to identify the problem field of industrial development and design an OTSW matrix of strategic analysis. The approach made it possible to define the key priorities in the strategic management system to ensure Russia’s technological independence in mechanical engineering. First, production and academia should unite to solve the problem of qualifications and competencies. Second, digital technologies are to form a consolidating system of digital management of technology development and implementation. The system will provide knowledge management, platform solutions, and expert-machine decision support. Eventually, it will diversify the tools of technological development and implementation, thus leading to public-private partnerships, strategic cooperation, and foreign investments that will fund further R&D projects. These priorities are comprehensive elements in the strategy for ensuring the technological independence of mechanical engineering in Russia. They are bound for success on the way to help the domestic mechanical engineering to cope with the current economic challenges.
Strategizing Knowledge Potential in Knowledge-Intensive Economy
Authors: Solntsev Artem
Published: December 2024

The growing importance of knowledge as a production factor in the early XX century led to the development of knowledge-intensive economy. Further research yielded the concepts of knowledge capital and knowledge potential. The current shift to knowledge-intensive economy also affects traditional industries, where knowledge is becoming a key competitive factor. The present research relied on the theory of strategy and the methodology of strategizing developed by Professor V.L. Kvint. The paper describes the main stages and elements of strategizing the knowledge potential. The author reviewed the concepts of human capital, knowledge capital, and knowledge potential defined by J. Schumpeter, F. Hayek, E. Phelps, O. Williamson, J.K. Galbraith, S. Kuznets, T. Schultz, G. Becker, T. Stewart, and V.L. Makarov to trace the existing approaches to the economic role of knowledge as a key economic resource. A number of case studies made it possible to visualize the concepts of knowledge potential, knowledge capital, and knowledge strategizing. The resulting stages of knowledge potential strategy covered the main trends, strategic interests, and opportunities. The strategizing of knowledge potential demonstrated a number of peculiarities, e.g., the explicit social nature of strategic interests. An efficient strategy for knowledge potential development should reflect the interests of all stakeholders because some of these interests may cancel each other.
Zagadnienie apelacji częściowej w procesie o stwierdzenie nieważności małżeństwa
Authors: Wieczorek Michał
Published: December 2024

Artykuł podejmuje problematykę apelacji częściowej w procesie o stwierdzenie nieważności małżeństwa. Analiza różnych dekretów wydanych przez sędziów Trybunału Roty Rzymskiej pozwala zrozumieć, jak sprawy takie traktowane są w tym apostolskim organie sprawiedliwości. Przedstawione dekrety dają szerokie spektrum dotyczące podejścia różnych turnusów do spraw, w których strona lub strony złożyły apelację częściową. Bardzo często apelacje takie są traktowane pod względem ich ewentualnej działalności na zwłokę (mere dilatria). Generalnie w takich przypadkach trzeba pamiętać o możliwości wykonalności wyroku z innych tytułów nieważności małżeństwa, co związane jest z pewną ekonomią procesową.
Synthesis, Reactions, and Biological Applications of 1,2,4-triazoles: A Review
Authors: Aly Ashraf A. , Hassan Alaa A. , Mohamed Nasr K. , Abd El-Aal Amal S. , Balboul Basma A. A. , Nayl AbdElAziz A. , Braese Stefan , Ramadan Mohamed
Published: December 2024

Compounds containing the 1,2,4-triazole substructure have been shown to have
broad biological activities. Many drugs with a 1,2,4-triazole structure have been developed
and proven: for example, ribavirin (antiviral), fluconazole, itraconazole, voriconazole (antifungal),
alprazolam (tranquilizer), estazolam (hypnotic, sedative), anastrozole, vorozole and
letrozole (as non-steroidal aromatase inhibitors). Given the importance of 1,2,4-triazole
scaffolds, the synthesis of their derivatives has attracted much attention. This review deals
with the synthetic methods of 1,2,4-triazole compounds in the past 20 years and illustrates
selected reactions of this class of compounds. Various biological activities of 1,2,4-triazoles
as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic,
analgesic, anti-inflammatory, and anthelmintic agents are also discussed.
Genetic Decoding Pulmonary Alveolar Proteinosis in Children: A Case Report
Authors: Panyala Aparna Reddy , Baladhandapani Kalai Selvi , yerra Anupama , Ahmed Hafsa , Moodahadu Latha Subramanya
Published: December 2024

Background:

Nonspecific symptoms and variable clinical course are the hurdles in diagnosing
pulmonary alveolar proteinosis (PAP), a rare lung disease. We report a pediatric case of
hereditary PAP caused by mutations in the gene encoding granulocyte Macrophage colony-stimulating
factor (GMCSF) receptor.

Case Presentation:

A 3 years 10-month-old female child, born to 3rd-degree consanguineous parents
presented with fever, intermittent cough, and breathing difficulty ten days before hospitalization.
Chest X-ray revealed bilateral diffuse alveolar infiltrates; Computed tomography (CT)
showed diffuse interstitial thickening along with a crazy pavement pattern. Bronchoscopy and
broncho-alveolar lavage (BAL) was performed. PAP was confirmed with BAL and genetic testing.
Serum GM-CSF autoantibody test was normal but serum GM-CSF concentration was high
(115.7 pg/mL). There was a continuous heterozygous deletion encompassing exon region 13 of
the SLC34A2 gene, suggestive of pulmonary alveolar microlithiasis. The patient received steroids (x2 weeks), inhalers (bronchodilators & steroids), and intermittent
home oxygen therapy (x2 weeks) with a good response.

Discussion:

Due to nonspecific symptomatology, and variation in disease severity, diagnosis of
PAP is delayed or missed. Crazy paving on CT, milky fluid on BAL with similar histological features
of foamy macrophages, and PAS-positive amorphous material within the alveolus are diagnostic
clues.
Asymptomatic patients or those with mild symptoms are managed with supportive care, monitoring,
and chest imaging; moderate to severe symptoms require whole lung lavage (WLL); GMCSF
Replacement therapy, an alternative to WLL Immunomodulation therapy is also considered.

Conclusion:

PAP can be managed conservatively with supportive therapy with good clinical outcomes
and not all patients require WLL. However, patient selection is crucial.
Techniques for Detecting Intelligent Phishing Attempts in An Insecure Socially Engineered Network Environment
Authors: Nanda Manika , Saraswat Mala , Sharma Pankaj
Published: December 2024

Phishing is an illicit attempt to obtain sensitive information from users, such as usernames,
passwords, and credit card details. Attackers often use disguised URLs to deceive web
users and steal private information. Attackers commonly employ social engineering tactics like
email and text messaging to facilitate phishing attacks. Active learning techniques, including neural
networks, can help identify and prevent phishing scams, though these methods have certain limitations.
This study provides a comprehensive review of various Artificial Neural Network approaches
that incorporate decision trees and optimal feature selection techniques to address these
challenges. We propose a newly developed feature assessment index that we can combine with an
optimal feature selection method. Techniques like decision trees, paired with local search methods,
are used to prune unnecessary features, enhancing the effectiveness of phishing detection.
The study also examines various social engineering attacks, particularly phishing websites, which
often serve as entry points for numerous fraudulent activities.
Optimization Analysis of Urban and Rural Environmental Planning Based on Artificial Intelligence and Intelligent Information Processing Algorithms
Authors: Zhao Feng , Han Chuanlong
Published: December 2024

Introduction:

With rapid economic development and urbanization, urban and rural areas
face environmental challenges. Traditional optimization methods struggle with complexity
and often fail to find global optima.

Method:

This study integrates a Bidirectional Long Short-Term Memory Network (BiLSTM)
with Genetic Algorithm (GA)-Ant Colony Optimization (ACO) to improve environmental planning.
BiLSTM captures long-term data correlations and predicts future trends, achieving an average
Mean Squared Error (MSE) of 0.0217. GA-ACO, using GA-generated solutions as initial input for
ACO, identifies optimal planning solutions.

Results:

This approach enhances air quality indicators and provides robust predictions and optimizations
for sustainable urban and rural development.

Conclusion:

To sum up, future development needs comprehensive technical progress, policy support
and public participation to form a multi-level and multi-field collaborative mechanism to
achieve the real sustainable development goal.
Voltage-Mode First-Order All-Pass Filter With Active Tuning
Authors: Bansal Khushbu , Mohan Jitendra , Chaturvedi Bhartendu
Published: December 2024

In this paper, a voltage-mode first-order all-pass filter using three passive components
(one capacitor, two resistors) and one active building block (second-generation voltage conveyor)
is presented. The proposed design's ideal and non-ideal behaviors are examined to ensure it functions
in real-world environments. The effects of variations in capacitance and temperature on the
performance of the proposed structure are also analyzed and verified through Monte Carlo simulations.
The proposed device gains a patented feature of tunability when NMOS transistors replace
two passive resistors with an active equivalent design. Moreover, a second-order all-pass filter
is included to test the design's practical viability. The circuit validation is conducted using 0.18
μm CMOS process parameters with a ±0.9 V power supply, using the PSPICE simulation tool,
and also validated by experimental setup using IC AD844.
Applications of Photovoltaic Water Pumping System in Developing Countries
Authors: Ali Faizan , Kumar Jitendra , Yadav Gaurav , Yadav Vikash
Published: December 2024

Background:

Indian agriculture is the backbone of the country's economy. As the population
increases, the need for water arises accordingly. The main challenge in the extraction and
transportation of water for agriculture and drinking purposes is high energy consumption. Among
the various alternatives, the best one is to use solar energy, which is abundant and nearly cost-free,
to power any industry, especially for irrigation. Photovoltaic (PV) solutions are the most suitable
for remote agricultural needs.

Objectives:

The present research aimed to study the challenge of the use of solar energy, energy
conversion initiatives, and the application of photovoltaic pumping systems in India and other developing
countries.

Methods:

Solar cells make up the smallest portion of a PV panel. Two or more distinct layers of
material known as semiconductors that have been specially prepared are present in every solar cell
and when exposed to light, these layers generate direct current (DC) electrical power. The electrical
wiring in the circuit board accumulates the DC. After conversion, it is then given to either a
DC pump or an AC pump, which pumps water while the sun shines.

Results:

Water pumps powered by solar energy are less expensive, have a silent operation, and require
less maintenance. Moreover, in addition to pumping water, PV panels can be used to generate
electricity for domestic use.

Conclusion:

Solar energy finds potential applications for agricultural uses, such as, irrigation, purification,
threshing aeration, and electrical fencing. Photovoltaic arrays of solar-powered water
pumping systems can be used to generate electricity, reducing the dependency on conventional energy
sources.
Chemical Composition and Biological Activities of Natural Essential Oil Extracted from Flowers of Cassia sophera Linn
Authors: Brahmachari Goutam , Majhi Sasadhar , Chatterjee Sohini , Mandal Bhagirath , Mandal Narayan Chandra , Chatterjee Suchandra
Published: December 2024

Background:

Natural essential oil comprises a galaxy of low-molecular-weight (usually less than 500 daltons) and volatile phytoconstituents that exhibit a
handful of biological and pharmaceutical properties; they exhibit several applications chiefly in agriculture, cosmetic, perfumeries, and food
industries.

Methods:

The extraction of essential oil from fresh flowers of C. sophera was performed by hydrodistillation, and the determination of its chemical
composition was carried out by Gas Chromatography/Mass Spectrometry (GC-MS). The antibacterial activity of the essential oil was executed by
the disc diffusion method against the four pathogenic bacteria. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) was also performed for free radical
scavenging assay, and a scanning electron microscopic study was also executed to get an idea of the effect of C. sophera essential oil on bacterial
morphology.

Results:

The GC/MS analysis indicated that the essential oil is constituted primarily of aromatic compounds (68.75%), and the principal compounds are the
dialkyl phthalates esters (58.32%). The zones of inhibition range from 8-16 mm in the case of Gram-negative E. coli, whereas, in Gram-positive S.
aureus, these range from 7-13.5 mm. The minimum inhibition concentration (MIC) was found to be 0.3 mg/mL against all the Gram-negative
bacteria tested and 0.4 mg/mL against the Gram-positive bacteria S. aureus. The oil also showed moderate antioxidant properties by scavenging
1,1-diphenyl-2-picrylhydrazyl (DPPH) radical with an IC50 value of 126 μg/mL.

Conclusion:

As per the present study, the essential oil of C. sophera flowers may be suggested as a new potential source of natural antimicrobial and
antioxidant agents.
In situ Epoxidation of Unsaturated Fatty Acid-based Corn Oil with Amberlite IR-120H as Catalyst
Authors: Azmi Intan Suhada , Abdul Yazid Nurul Umairah , Jalil Mohd Jumain
Published: December 2024

Introduction:

Studies using sustainable and environmentally friendly raw materials
are prominent among researchers due to rising environmental concerns.

Objective:

This study aimed to produce epoxidized corn oil using in situ peracid formation, with
Amberlite IR-120H as a catalyst, alongside acetic acid and hydrogen peroxide.

Materials and Methods:

Expoxidized corn oil was produced in situ with acetic acid as an epoxidation
agent and Amberlite as a catalyst. Results: The results showed that using a 50% concentration
of hydrogen peroxide and a 0.5:1 molar ratio of hydrogen peroxide to corn oil achieved
the highest Relative Conversion to Oxirane (RCO).

Discussion:

In situ epoxidation resulted in a higher relative conversion to oxirane in reaction
time (60 minutes).

Conclusion:

Lastly, numerical simulations were executed employing a genetic algorithm, and
the outcomes exhibited a noteworthy congruence between the simulated data and the empirical
observations.
Finite Element Analysis of Failure Pressure of X100 Oil and Gas Pipeline with Double Defects
Authors: Wang Zhanhui , Li Dongze , Duan Wenlong , Wang Aimin , Li Xiaojun , Zhang Zhifang
Published: December 2024

Background:

At present, natural gas and crude oil are significant for the national
economy, and their safe transportation is crucial. The integrity of pipelines is the key to
ensuring this goal.

Objective:

We take X100 pipeline as the research object and use ANSYS software to complete
finite element simulations of three types of pipeline models: double external defect,
double internal defect and double internal and external defect.

Methods:

ANSYS software was adopted to study three types of pipeline models: double
external defect, double internal defect and double internal and external defect. Firstly, the
way defect parameters (defect depth and defect length) affect pipeline failure pressure is
evaluated. Then, the failure pressure calculation results are fitted with formulas using
MATLAB software, and the accuracy and applicability of the fitting formulas are verified.

Results:

For the three types of double defect pipeline models, namely double external defect,
double internal defect, and internal and external defect, in terms of the impact of defect
depth, failure pressure decreases with increasing defect depth. In terms of the impact
of defect length, the failure pressure decreased as the defect length increases. The overall
average error for the three pipeline models between MATLAB fitting formula results and
three standards results are 5.25%, 7.07%, 7.43%, respectively, a relatively low level of error,
indicating the MATLAB fitting formula has high reliability and accuracy. The sum of
squared correlation coefficients (R2) for the three pipeline models are 0.9190, 0.97837, and
0.97797, respectively, indicating the fitting formula has a high degree of fitting. The serial
numbers with pressure ratios greater than 1 for the three pipeline models are 67, 92, and
98, respectively, indicating the double external defect pipeline model performs the best,
followed by the double internal defect pipeline model, and the double internal and external
defect pipeline model performs the worst.

Conclusion:

These findings can be applied to improve the assessment of failure pressure in
X100 pipelines, leading to more effective maintenance and inspection strategies.
Transient Empirical Machine Learning Models based on Bit Coin Price Prediction using High and Low Values
Authors: Gupta Charu , Rehani Shrey , Kumar Prakhar , Yadav Pranjay , Jatana Nishtha , Singh Shweta
Published: December 2024

Introduction:

Cryptocurrency is the new mode of transaction that is slowly replacing
the conventional assets of transactions. With the rise and advancement in the technology
called blockchain and the volatile nature of the market, cryptocurrencies are showing possibilities
of making huge profits. This new trend is slowly becoming accessible to all classes of society
in every part of the world while creating a great opportunity for scholars and analysts to
conduct new research. However, unlike the stock market, the prices of cryptocurrencies show
highly volatile and dynamic behaviour.

Methods:

Several research in the past have been performed to predict the nature and other aspects
of cryptocurrencies with the aid of machine learning to forecast the future market based
on past data. In the proposed work, 6 different machine-learning models have been used for
forecasting the prices of cryptocurrencies. The algorithms used are Autoregressive Integrated
Moving Average (ARIMA), Gated Regression Unit (GRU), Long Short-Term Memory
(LSTM), Bi-LSTM and Vector Autoregression (VAR).

Results:

Further, the accuracies of different models are compared and analysed. Furthermore,
these models are used to predict the first-order difference between 24 hours of all-time high
and low values. This evaluation gives us an idea of where the price band of the currency and
where is it most likely to be present during any 24-hour timespan.

Conclusion:

This can effectively lead to better decision making in choosing crypto-currency.
The GRU model achieved the best performance in cryptocurrency prediction with an RMSE of
0.2242 and MAE of 0.1598 for BTC prices, while the LSTM followed closely with an RMSE
of 0.3473 and MAE of 0.2557. Both models outperformed ARIMA, Bi-LSTM, VAR, and FB
Prophet, which showed significantly higher error rates.
effect of good corporate governance on company value in LQ45 companies listed on the Indonesia Stock Exchange
Authors: Marissa Marissa , Isnurhadi Isnurhadi , Widiyanti Marlina , Fu'adah Luk Luk
Published: December 2024

This study aims to analyze the effect of Good Corporate Governance (GCG) on firm value in LQ45 companies listed on the Indonesia Stock Exchange (IDX) for the 2019-2023 period. GCG is proxied through managerial ownership, institutional ownership, audit committee, and independent board of commissioners, while firm value is measured using Tobin's Q. The research method used purposive sampling with a sample of 19 companies. The data were analyzed using multiple linear regression through SPSS software version 25. The results showed that: (1) managerial ownership has a positive but insignificant effect on firm value, (2) institutional ownership has a significant positive effect on firm value, (3) independent board of commissioners has a significant negative effect on firm value, and (4) audit committee has no significant effect on firm value. These results indicate that GCG implementation still varies in influencing firm value in Indonesia.
Os lugares finais do poema
Authors: Martins Ana Luísa
Published: December 2024

Despite having taken distinct paths and hailing from distant places, Paul Celan and Herberto Helder meet in their writings through the way in which they contemplated the problem of the poetic “topos”: through the refusal of the arbitrary prison of a native land, as well as through the search of a “crossing of the tropics”, beyond literary and land borders, on their poetic works. Thus, this article proposes a comparative study between Paul Celan and Herberto Helder with this question as the starting point: is a poem forever stuck to its origins or is it instead heading to a final destination, a place, a self-created address in which it can inhabit?