bluuebunny/crossref_metadata_2025 huggingface dataset:
Survival Rate of Liver Transplantation in Asia: A Systematic Review and Meta-Analysis
Authors: Ghelichi-Ghojogh Mousa , Rajabi Abdolhalim , Mohammadizadeh Fateme , Shojaie Layla , Vali Mouhebat , Afrashteh Sima , Hassanipour Soheil , Nikbakht Hossein-Ali , Khezri Rozhan , Kalteh Ehsan Allah , Fararouei Mohammad
Published: October 2022

Background: Liver transplantation is one of the most effective treatments for acute liver failure, chronic liver cirrhosis, and hepatocellular carcinoma. This study was implemented to evaluate the survival rate of liver transplant in Asia.
Methods: Studies that investigated the survival rate of liver transplant were selected using a systematic search strategy in the following databases: Medline, Embase, Scopus, ProQuest, ISI Web of Science, and Cochrane to Nov 30th, 2020. Pooled survival rate and 95% confidence intervals were calculated using Der-Simonian and Laird method. Stata 16.0 (Stata Corp, College Station, TX, USA) was used for analysis.
Results: One, 2, 3, 5, and 10-year survival rates of liver transplant were estimated to be 85%, 80%, 75%, 73%, and 71%, respectively. The results of the univariate meta-regression for defining the sources of heterogeneity for one-Year survival rate (SR) showed significant effects of bias (β high risk/ moderate risk =0.059, 95% CI: 0.002, 0.115, P-Value=0.04) and follow up time (β=-0.0002, 95% CI: -0.0003, -0.00, P-Value=0.02) on heterogeneity.
Conclusion: The survival rate of liver transplant in Asia is comparable with the corresponding rate reported in the United States and Europe. This study provides a better view of the efficiency of medical cares, regarding liver transplantation. Medical care be enhanced to increase the survival of liver transplant patients.
Cirrhosis Due to Alcohol-Related Liver Disease Hospitalizations in Belgrade, Serbia: A 10-Year Retrospective
Authors: Milovanovic Tamara , Lugonja Sofija , Pantic Ivana , Miltenovic Svetlana , Vlaisavljevic Zeljko , Mardani Abbas
Published: October 2022

Background: Cirrhosis due to alcohol-related liver disease (ALD cirrhosis) is a significant burden to health systems worldwide. We aimed to determine the trends in hospitalization frequency due to ALD cirrhosis and to analyze their characteristics.
Methods: This cross-sectional study used data from the Institute of Public Health of Belgrade database, and included all hospitalization reports which contained code K70.3 (Cirrhosis hepatis alcoholica) as the primary diagnosis, including re-hospitalizations, on the territory of Belgrade, between January 2009 and December 2018.
Results: A total of 4644 patients with ALD cirrhosis were hospitalized (male: 4154, 89.45%), with a mean age of 58.83±10.02 years. During the 2009-2018 decade, no difference in the number of ALD cirrhosis hospitalizations in subsequent years was observed. Men more commonly developed esophageal and gastric varices with bleeding compared to women (P=0.037), while women developed acute-on-chronic liver failure (ACLF) almost two-times more often compared to men (P<0.001). Patients with hepatocellular carcinoma were significantly older (P<0.001), while those who developed ascites and splenomegaly were significantly younger compared to those who did not (P<0.001 and P=0.04, respectively). Altogether, complications of portal hypertension were registered and reported with very low frequency, and therefore do not represent actual frequencies of these conditions. The median duration of hospital stay was 9 days (range 0-243). Patients in whom lethal outcome occurred during the hospitalization were significantly older, and more commonly developed chronic renal failure.
Conclusion: These data offer an important insight into the ALD cirrhosis-related hospitalizations while drawing attention to inadequate coding as an important public health issue at the same time.
Lncrna FGD5-AS1 Aggravates Myocardial Ischemia-Reperfusion Injury by Sponging Mir-129-5p
Authors: Wei Peng , Dong Zhifeng , Lou Ming
Published: October 2022

Background: LncRNA FGD5-AS1 regulates the pathogenesis of many human diseases. We aimed to elucidate the function of lncRNA FGD5-AS1 and the regulatory mechanism of lncRNA FGD5-AS1/miR-129-5p in myocardial ischemia-reperfusion (I/R) injury.
Methods: Myocardial I/R injury mice model and H/R treated H9c2 cells were established. RT-qPCR and Western blot analysis were used to detect the mRNA and protein expression. Cell viability was detected by MTT assay. Dual luciferase reporter assay was applied to confirm the relationship between lncRNA FGD5-AS1 and miR-129-5p.
Results: LncRNA FGD5-AS1 was upregulated in myocardial I/R injury mice models and H/R treated H9c2 cells. Functionally, knockdown of lncRNA FGD5-AS1 promoted cell viability and inhibited apoptosis in H/R treated H9c2 cells. In addition, lncRNA FGD5-AS1 directly targets miR-129-5p. Upregulation of lncRNA FGD5-AS1 weakened the protective effect of miR-129-5p on myocardial I/R injury.
Conclusion: LncRNA FGD5-AS1 aggravates myocardial I/R injury by downregulating miR-129-5p.
Evaluation of Breast Cancer Incidence Trends in the Karaganda Region of Kazakhstan
Authors: Igissinov Nurbek , Toguzbayeva Asem , Telmanova Zhansaya , Baibusunova Aida , Abdykalikova Almazhan , Igissinova Gulnur , Bilyalova Zarina , Akyshev Olzhas , Orazbayev Serikbay , Kozhakhmetova Zhanar , Azhetova Zhanerke , Nurtazinova Gaukhar , Kuandykov Yerlan
Published: October 2022

Background: The study conducted a component analysis of the dynamics of the incidence of breast cancer (BC) in Karaganda region.
Methods: Primary data were for registered patients with BC (ICD 10–C50) in Kazakhstan, Karaganda region the period of 2009-2018. Evaluation of changes in BC incidence in the population of Karaganda was performed using component analysis according to the methodological recommendations.
Results: Overall, 4,391 new cases of BC and 1,202 deaths were recorded. The incidence rate increased from 44.4 (2009) to 72.7 in 2018 and the overall growth was 28.37 per 100,000 population of female, including due to the age structure – ∑ΔA=3.13, due to the risk of acquiring illness – ∑ΔR=22.69 and their combined effect – ∑ΔRA=2.56. The component analysis revealed that the increase in the number of patients with BC was mainly due to the growth of the population (ΔP=+3.7%), changes in its age structure (ΔA=+10.3%) and changes associated with the risk of acquiring illness (ΔR=+75.0%). The mortality rate in the region changed from 18.6 (2009) to 10.9 (2018) and tended to decrease.
Conclusion: The role of the influence of demographic factors and the risk of acquiring illness on the formation of the number of patients and the incidence of BC was evaluated. In this region, these indicators were the highest. The implementation of the results of this study is recommended in management of anticancer activities for BC.
G Protein Coupled Receptors Potentially Involved in Oligodendrogenesis: A Gene Expression Analysis
Authors: Karami Neda , Aligholi Hadi , Rahimi Moosa , Azari Hassan , Kalantari Tahereh
Published: October 2022

Background: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system characterized by infiltration of inflammatory leukocytes to the CNS followed by oligodendrocyte cell death, myelin sheath destruction, and axonal injury. A logical incidence occurring after demyelination is remyelination. G-protein coupled receptors (GPCRs) activate internal signal transduction cascades through binding to different ligands. This family of receptors are targeted by more than 40% of currently marketed drugs. GPCRs can be successfully targeted for induction of remyelination. GPCRs highly enriched in oligodendrocyte progenitor cells compared to oligodendrocytes are proposed to hamper oligodendrocyte differentiation and therefore their inhibition might induce remyelination. This study aimed to investigate the expression of GPCRs in silico and in vitro.
Methods: We performed gene expression analysis using DAVID and Panther websites on a RNA-seq dataset (GSE52564 accession number). Primary embryonic neural stem/progenitor cell isolation and culture were performed and subsequently NSPCs were characterized by Immunocytochemistry with Anti-Nestin antibody. Expression of GPR37L1, EDNRB, PDGFRα, CNPase and GFAP were assessed using real-time PCR. All the experiments were conducted at Shiraz University of Medical Sciences (SUMS), Shiraz, Iran, in the year 2018.
Results: The 14 most highly expressed GPCRs in oligodendrocyte progenitor cells (OPCs) compared to Oligodendrocytes were presented in our study.
Conclusion: The investigation of the most highly expressed GPCRs in OPCs compared to oligodendrocyte in silico and in vitro presents the significant role of GPCRs in remyelination induction. Among the 14 GPCRs mentioned in this study, GPR37L1 is a potential remyelinating drug target and is suggested for further studies.
Can a Single General Self-Rated Health Question Mirror Social Determinant of Health?
Authors: Rezaei Zahed , Keshavarz Mohammadi Nastaran , Pouragha Hamidreza , Shakibazadeh Elham
Published: October 2022

Background: Self-rated health (SRH) indicator is widely used and recommended in health research as a standard indicator for measuring health in different populations. This paper reports SRH of employees at Tehran University of Medical Sciences (TUMS), Tehran, Iran; and its related factors.
Methods: We used the TUMS Employee's Cohort Study (TEC) data, collected from September 2017 to August 2019. SRH of 2158 employees were assessed using a single question. Univariate and multivariate logistic regression were performed to determine factors associated with sub-optimal SRH.
Results: Overall, 14.9% (n = 321) of respondents rated their health as sub-optimal. Differences were observed with subgroups. Women, lowersocioeconomic status (SES), experiences of more economic fluctuation conditions and lower reading scores could predict sub-optimal SRHvariations in crude and adjusted regression analyses. The age, social capital, work experience and employment status could predict sub-optimal SRH variations only in crude regression analyses (P<0.05).
Conclusion: Differences in SRH report reflected differences in socioeconomic conditions. The biggest gap was observed between people of different SES (five times). Considering that SRH reflected socioeconomic characteristics of individuals, it may be considered as a quick, non-expensive, and simple way of identifying groups in need of addressing their social determinants of health.
Incidence and Economic Burden of Rhinoplastyin Tehran, Iran
Authors: Bidkhori Mohammad , Akbarisari Ali , Yaseri Mehdi , Majdzadeh Reza
Published: October 2022

The Article’s Abstract is not available.
Factors for Adsorption Mechanism to Remove 1,2-Dichlorobenzene Using Carbon Nanotubes in a Water Treat-ment System
Authors: Lee Do Gyun
Published: October 2022

The Article’s Abstract is not available.
Prophylactics of Type 2 Diabetes and Diabetic Foot
Authors: Vakrilova Becheva Maria S. , Kirkova-Bogdanova Angelina G.
Published: October 2022

The Article’s Abstract is not available.
Effects of Menopause on Physical Activity and Dopamine Signaling in Women
Authors: Kim Dong-Il , Park Young-Min
Published: October 2022

The Article’s Abstract is not available.
Can the Target of 40% Stunting Reduction by 2024 Be Reached?
Authors: Siswati Tri , Iskandar Slamet , Pramestuti Nova , Raharjo Jarohman , Rubaya Agus Kharmayana , Wiratama Bayu Satria
Published: October 2022

The Article’s Abstract is not available.
On history and liberty: the ‘revisionism’ of Bronisław Baczko
Authors: Baiao Helder Mendes
Published: October 2022

The ‘Warsaw School of History of Ideas’ is the name given to a ‘revisionist think tank’ which was led by the historian Bronisław Baczko from 1956 to 1968 in Communist Poland. This group reunited scholars like Leszek Kołakowski or Krzysztof Pomian around questions related to political believes, theological conceptions or utopian thought. Expelled from the University, B. Baczko left Poland and seek shelter in Geneva where he became a Professor of history of Ideas and historiography. In his new home, he developed an original vision on Enlightenment and the French Revolution.
From interpretation to refutation of marxism. On Leszek Nowak’s non-marxian historical materialism
Authors: Brzechczyn Krzysztof
Published: October 2022

The aim of this article is to outline the theory of a historical process developed within the framework of the Poznań School of Methodology, mainly by Leszek Nowak and a team of his co-workers. In the first part of the paper, the meta-philosophical and meta-theoretical assumptions of Poznań school are reconstructed and juxtaposed with the relevant assumptions of Western analytical Marxism. In the central part of the paper, the main ideas of adaptive reconstruction of historical materialism and non-Marxian historical materialism are presented. In its final part, some problems of reception of Leszek Nowak’s  theory of historical process in Polish People’s Republic and the Third Republic are discussed.
The false dichotomy between causal realization and semantic computation
Authors: Miłkowski Marcin
Published: October 2022

In this paper, I show how semantic factors constrain the understanding of the computational phenomena to be explained so that they help build better mechanistic models. In particular, understanding what cognitive systems may refer to is important in building better models of cognitive processes. For that purpose, a recent study of some phenomena in rats that are capable of ‘entertaining’ future paths (Pfeiffer and Foster 2013) is analyzed. The case shows that the mechanistic account of physical computation may be complemented with semantic considerations, and in many cases, it actually should.
Evaluation by electrical bioimpedance method of selected morphological parameters of the body of women aged 19 to 26 not engaging in physical activity
Authors: Całyniuk Beata , Malczyk Agata
Published: October 2022

Wstęp

Niewłaściwe odżywianie i brak aktywności ruchowej sprzyjają rozwojowi wielu schorzeń, początkowo nie dających objawów klinicznych, dlatego regularne monitorowanie stanu zdrowia jest niezbędne dla jego zachowania. Podstawowym badaniem wykorzystywanym w ocenie stanu odżywienia indywidualnych osób, a także wybranych populacji jest analiza składu ciała. Celem pracy była ocena składu ciała kobiet w wieku 19–26 lat niepodejmujących aktywności fizycznej.

Materiał i metody

W badaniu wzięło udział 548 kobiet w wieku 19–26 lat. Oceny składu ciała dokonano za pomocą analizatora wykorzystującego metodę bioimpedancji elektrycznej. Badanie pozwoliło na uzyskanie informacji na temat zawartości tkanki tłuszczowej i beztłuszczowej w organizmie, masy mięśni, masy mineralnej kości, całkowitej zawartości wody, z uwzględnieniem wody wewnątrzkomórkowej i zewnątrzkomórkowej oraz proporcji wody zewnątrzkomórkowej do całkowitej, a także wskaźnika masy ciała (body mass index – BMI), wskaźnika tkanki wisceralnej, wieku metabolicznego i podstawowej przemiany materii.

Wyniki

Ponad 75% badanych kobiet w wieku 19–26 lat miało prawidłową masą ciała, a prawie 90% prawidłową zawartość wody w organizmie. Jednak u 86,7% badanych stosunek wody zewnątrzkomórkowej do całkowitej zawartości wody w organizmie był podwyższony. Stosunek wody zewnątrzkomórkowej do całkowitej zawartości wody w organizmie wzrastał istotnie statystycznie wraz z wiekiem. U prawie 45% badanych występowała zbyt duża (na poziomie podwyższonym i wysokim) zawartość tkanki tłuszczowej w organizmie. Wiek metaboliczny u co trzeciej badanej kobiety był wyższy niż wiek metrykalny.

Wnioski

Lepszym stanem odżywienia – w porównaniu z pozostałymi badanymi – ocenianym na podstawie BMI i analizy składu ciała charakteryzowały się kobiety w wieku 21 lat.
Comportement Biophysique et Écophysiologique de Cinq Espèces Ligneuses en Plantation dans la Commune Rurale de Massala (Cercle de Ségou, Mali)
Authors: Kassambara Ousmane , Sénou Oumar , Sylla Moussa , Karembé Moussa , Sambaké Ibrahim
Published: October 2022

Au Mali, très peu d’études écophysiologiques ont été menées sur les espèces ligneuses notamment à leur stade juvénile. L’objectif de cette étude était d’évaluer le comportement biophysique et écophysiologique de cinq espèces ligneuses en plantation. Pour ce faire, les plants de trois espèces autochtones (Combretum micranthum, Combretum glutinosum et Piliostigma reticulatum) et deux espèces exotiques (Acacia auriculiformis et Cassia siamea) ont été produits en pépinière et transplantés à l’âge de 4 mois dans un dispositif expérimental en blocs de Fisher avec 4 répétitions. Par la suite, les paramètres biophysiques (taux de survie, diamètre au collet et hauteur totale des plants) ont été évalués 29 mois après plantation alors que les paramètres écophysiologiques ou traits fonctionnels (teneur relative en eau (RWC), surface foliaire spécifique (SLA) et teneur en matière sèche foliaire (LDMC)) ont été évalués entre 12 et 24 mois après plantation pendant 4 périodes distinctes de l’année. Comme résultats obtenus, le taux de survie a varié en fonction des espèces étudiées. De même, pour la croissance en hauteur et en diamètre, il a été obtenu une différence hautement significative (P<0,001) entre les cinq espèces. Concernant les traits fonctionnels, la teneur relative en eau a varié significativement en fonction d’une part de la période de l’année et d’autre part de l’espèce alors que l’interaction des deux facteurs a eu un effet significatif sur la surface foliaire spécifique et la teneur en matière sèche foliaire des plants. Enfin, globalement tous les traits fonctionnels étudiés étaient significativement corrélés entre eux.
Coreografias de gênero em covers de K-pop
Authors: Soares Thiago , Silva Lúcio Souza Ferreira da
Published: October 2022

Grupos covers de K-pop (K-covers) corporificam seus ídolos sul-coreanos em práticas coreográficas online e offline ao mesmo tempo que, a partir da especificidade de seus corpos, coreografam o gênero em suas aparições performáticas. A relevância desta investigação está em apresentar ferramentas teórico-metodológicas para a análise de fenômenos da cultura pop (os covers), a partir das intersecções das noções de interculturalidade e dos estudos de gênero. Apresenta, como metodologia, a análise de vídeos de grupos covers de K-pop em que jovens LGBTQIA+ (negros, gordos e trans) reencenam coreografias de girl groups (grupos de garotas) de K-pop promovendo rasuras performáticas interculturais. Como resultado, apresenta a ressignificação do aegyo (aqui pensado como “fofura” dos grupos femininos de K-pop) que, coreografado por jovens LGBTQIA+ em contextos fora da Coreia do Sul, operam sob a lógica do close, da fechação e do lacre.
Diálogos entre a Teoria do Conceito e organização do conhecimento arquivístico
Authors: Gonçalves Jéssica dos Santos , Tognoli Natália Bolfarini
Published: October 2022

Compreendendo a organização como um processo mediador entre a produção e o acesso e uso dos documentos de arquivo e das informações que eles carregam, este trabalho aborda as relações da Arquivologia com a Ciência da Informação. A transversalidade com a Organização do Conhecimento é ponto de partida, a partir dos estudos de uma de suas teorias basilares: a Teoria do Conceito. Para tanto, realizou-se uma Revisão Sistemática de Literatura, tendo como campo empírico bases de dados em Ciência da Informação e anais dos eventos internacionais e nacionais da International Society for Knowledge Organization. Os resultados demonstram que no âmbito da organização do conhecimento arquivístico, a presença da Teoria do Conceito ainda é tímida, sendo utilizada tanto como método de análise de conceitos da própria Arquivologia quanto como fundamento à construção de sistemas de organização do conhecimento arquivístico mais completos.
Gestão da informação e monitoramento da marca em mídias sociais
Authors: Dutra Frederico Giffoni de Carvalho
Published: October 2022

Estudo de caso na Companhia Energética de Minas Gerais referente aos procedimentos adotados para a gestão da informação e monitoramento da marca nas mídias sociais. A coleta de dados se deu por meio de entrevista estruturada, realizada a partir de um roteiro de perguntas com os integrantes da equipe de comunicação da Companhia Energética de Minas Gerais responsáveis pela atividade de monitoramento em mídias sociais. Após a aplicação do modelo de gestão da informação de Dutra, de 2020, à realidade da empresa, os resultados apontaram necessidades de melhoria nas etapas de disseminação e avaliação do processo de gestão da informação, aliada uma cultura de compartilhamento de informações, aprendizado e acompanhamento contínuo de indicadores e métricas.
Tradução e validação de conteúdo do instrumento para avaliação da Gestão do Conhecimento holística
Authors: Corrêa Fábio , Carvalho Dárlinton Barbosa Feres , Zaidan Fernando Hadad , Ribeiro Jurema Suely de Araújo Nery , Faria Vinícius Figueiredo de
Published: October 2022

A Gestão do Conhecimento é uma temática de interesse crescente por parte de pesquisadores. Como um meio para abordar a realidade dessa temática são propostos instrumentos para avaliação, mas esses instrumentos demandam de validação de conteúdo para conferir qualidade aos mesmos. Neste sentido, esta pesquisa tem por objetivo promover a tradução e a validação de conteúdo do instrumento de avaliação da Gestão do Conhecimento holística de Corrêa e outros, de 2021, de modo a conferir qualidade a versão traduzida do português para o inglês. Os procedimentos metodológicos consistem na tradução das afirmativas do instrumento por um pesquisador doutor, fluente em ambas as línguas e especialista na temática, com suporte das ferramentas Google Translate e Grammarly. Por conseguinte, a tradução foi avaliada por três doutores e especialistas em Gestão do Conhecimento, proficientes em ambas as línguas, e validada por meio do método de Coeficiente de Validade de Conteúdo, considerando os aspectos de clareza, coerência e tradução. Os resultados revelaram que os scores 0,98, 0,97 e 0,97 para os respectivos aspectos atestam a qualidade da versão traduzida. Assim, espera-se que o instrumento traduzido possa ser útil para uso de pesquisadores que demandem dessa versão.
Abordagens temáticas da competência em informação
Authors: De Lucca Djuli Machado , Neubert Patricia da Silva
Published: October 2022

Aborda o desenvolvimento da pesquisa sobre Competência em Informação, por meio de análise temporal das temáticas da produção científica sobre o tema. O universo do estudo é composto pelos documentos sobre Competência em Informação indexados na coleção principal da Web of Science entre 1974 e 2019. A análise das temáticas é baseada nas palavras-chave atribuídas pelos autores. Foram identificadas 6.108 palavras-chave, somando 15.289 menções, em 2.918 documentos. Os descritores foram associados as fases de desenvolvimento do movimento da Competência em Informação, de 1974-1989, 1990-1999, 2000-2009, 2010-2019. A análise temporal indica diminuição da variabilidade terminológica, apontando a consolidação de temas de estudo e de consenso terminológico no decorrer dos anos. Foram identificados termos associados à Biblioteconomia e ensino desde a primeira fase, com a inclusão gradativa de descritores associados as tecnologias a partir de 1990. Estudos incluindo públicos específicos, notadamente vinculados ao ensino superior e aos usuários de bibliotecas incorporam-se posteriormente, agregando movimentos adjuntos associados a estas temáticas. Na última fase há a manutenção da ênfase nas especialidades e público já incorporados e o desenvolvimento de uma perspectiva crítica nesse contexto. Os resultados sugerem, a partir da fase inicial, períodos de consolidação, desenvolvimento e expansão da Competência em Informação, que podem ser utilizados para demarcação do desenvolvimento da área.
Eficiência de softwares nacionais e internacionais na detecção de similaridade e de plágio em manuscrito
Authors: Krokoscz Marcelo
Published: October 2022

Este estudo visa identificar a eficiência de quatorze softwares de detecção de similaridades em um texto com fragmentos sobre educação financeira, encontrados em websites da internet, anais de eventos acadêmicos e revistas científicas de acesso aberto e restrito. Os fragmentos foram usados para elaborar um texto coeso, escrito em língua portuguesa, contendo reproduções textuais literais, paráfrases, com trechos traduzidos do idioma inglês, manipulados com inserção de caractere oculto e com substituição de palavras por sinônimos. Os relatórios de similaridade gerados pelos softwares foram analisados de acordo com quatro critérios: 1 identificação de fragmentos citados corretamente; 2 identificação de fragmentos plagiados; 3 identificação de textos manipulados para enganar o software; 4 identificação de fontes originais; os quais foram pontuados em uma escala de 0 a 4 pontos. Os softwares Turnitin, StrikePlagiarism, PlagScan e Plagium tiveram performance elevada e CopySpider e Plagium (complemento do Google) foram os mais ineficientes. Constatou-se que os softwares operam com eficiência variável, o que reforça a convicção de que embora sejam ferramentas úteis para a identificação de plágio, contribuem de forma limitada para aspectos como reconhecimento de reproduções textuais literais que nem sempre correspondem à fonte original. As fontes originais de textos reescritos, manipulados e traduzidos não foram encontradas por nenhum software. O estudo contribui para o aprimoramento da capacidade do usuário na escolha, uso e análise dos relatórios de similaridades gerados por softwares, cuja eficiência pode ser maior no caso da utilização de mais de um software.
Metadados de assuntos de teses e dissertações em repositórios
Authors: Fujita Mariângela Spotti Lopes , Ribas Rosane , Rodrigues Milena , Silveira Telma
Published: October 2022

Os metadados de teses e dissertações são inseridos nos repositórios automaticamente ou manualmente, em formato Dublin Core, diferente do utilizado pelas bibliotecas, gerando duplicidade de trabalho. O objetivo é comparar os procedimentos de tratamento temático de teses e dissertações existentes no catálogo on-line e no repositório, por meio da análise de metadados de assunto. Realizou-se estudo exploratório com estudo de caso sobre o uso de controle de vocabulário em metadados de teses e dissertações, com o repositório institucional da Universidade Estadual Paulista e o catálogo on-line Athena da mesma instituição. O estudo exploratório teve duas etapas: estudo documental da trajetória histórica de tratamento de teses e dissertações da universidade e análise de procedimentos de tratamento temático de teses e dissertações nas bases de dados, por autores e catalogadores. A análise de procedimentos de tratamento temático empregou observação de funcionamento e de rotinas e padrões, para avaliação de controle de vocabulário na análise de metadados de assuntos. Os resultados obtidos revelaram que o controle de vocabulário não é feito nas interfaces de busca para recuperação da informação e nem na lista alfabética de palavras-chave, o que significa falta de orientações aos autores, quanto à atribuição de descritores. As análises demonstraram dois tratamentos temáticos, cujos resultados são diferentes representações de assuntos, em linguagem natural, no repositório, e em linguagem controlada, no catálogo. Foram elaboradas duas propostas para o tratamento temático em metadados de assunto de teses e dissertações em repositórios e catálogos de bibliotecas. Conclui-se que as propostas poderão ser auxiliadas pela elaboração de uma política de indexação do repositório que preveja o compartilhamento de dados resultantes do autoarquivamento de teses e dissertações com o catálogo e que possa aceitar a atribuição de descritores de vocabulário controlado, além da atribuição de palavras-chave.
The Application Plan of Cognitive Interview and Scientific Content Analysis (SCAN) Techniques in the Case Analysis on Military Deaths
Authors:   The Korean Academy of Scientific Criminal Investigation, Shin Seong-Kweon
Published: October 2022

As a result of analyzing the interview details of 21 deaths in the military, One of the most important factors to be considered during an investigation interview is that a location suitable for the conditions must be selected in the interview preparation stage to obtain accurate and abundant information. In the interview stage, a consensus is formed through the formation of a rapport with the witness, In order to obtain concrete and factual statements related to the case, you must first plan and interview how you will be able to make a statement through the cognitive interview technique. and It is important to examine the possibility of using the investigation by analyzing whether the statements of the persons involved in the case are reliable and valid. In this study, the criteria of scientific content analysis were examined, and the statements of the people involved in 21 death cases were substituted into the criteria of scientific content analysis to analyze the statements of the people involved. In the future, by applying cognitive interview and scientific content analysis (SCAN) to investigative interviews, it is expected that if the verbal and non-verbal behavioral responses of the witnesses are observed and the credibility of the statements is verified, it will be an opportunity to increase the efficiency of human investigations.
Oxytocin dynamics in the body and brain regulated by the receptor for advanced glycation end-products, CD38, CD157 and nicotinamide riboside
Authors:   Kanazawa University, Higashida H. , Gerasimenko M.N. ,   Kanazawa University
Published: October 2022

Oxytocin in brain neurons is secreted somato-axono-dendritically and CD38-dependent fashion into the brain and released from the nerve terminals in the posterior pituitary into the circulation.Regarding possible candidates, we suspected the receptor for advanced glycation end-products (receptor for AGEs, RAGE) transports OT from the peripheral blood into the brain by RAGE in endothelial cells at the BBB.
Pathogenetics of Internet addiction in adolescents
Authors:   Research Institute of Medical Problems of the North, Smolnikova M.V. , Tereshchenko S.Y. ,   Research Institute of Medical Problems of the North
Published: October 2022

Th e aim of the research. Internet addiction (IA) is a relatively new psychological phenomenon having signs of a social epidemic, specifi cally attributed to vulnerable groups (adolescents). Th e prevalence of IA among adolescents varies depending on the studied ethnosocial groups and the diagnostic criteria. In Europe, the prevalence of IA among adolescents is on average 4.4 % [1]. In Asian countries (China, South Korea, Japan, etc.), the prevalence of IA is signifi cantly higher – 8.1-26.5 % [2]. Th e genetic component of developing Internet addiction was shown by twin studies using various populations, however, to date, the specifi c genes involved in the mechanisms of such heritability are not exactly identifi ed [3]. Th e purpose of with work was to study the prevalence of Internet addiction options, diff erent in severity, addiction pattern and content, in adolescents from ethnically diff erent cities, to assess the frequency of mental and somatic comorbidity in selected groups, to investigate the associative role of candidate neurotransmitters and to conduct a population analysis of polymorphisms of candidate genes oxytocin-, dopamine-, serotonin-, norepinephrine-, melatoninand nicotinergic neurotransmitter systems. Material and methods. Th e study of genetic predisposition to IA included adolescents living in Krasnoyarsk (n = 359), adolescents from Abakan (n = 150) and from Kyzyl (n = 200). In total 16 SNPs were genotyped by RT-PCR. Results. For the fi rst time, data were obtained on the prevalence of IA among urban adolescents in Central Siberia – pathological Internet addicted behavior was registered in 6.8 % of an unbiased school sample in Krasnoyarsk (using a CIAS scale). Th e Internet addiction structure was as follows: Adaptive Internet Usage (expected frequency 60-75 %), revealed frequency – 46.9 %; Non-adaptive Internet Usage (expected frequency 20-30%), revealed frequency – 31.3 % and Internet Addiction (expected frequency 5-10 %), revealed frequency – 21.8. It is noteworthy that the frequency of non-adaptive adolescents among Tuvans is 45 %. Conclusion. Genotypes including the T allele rs1044396 CHRNA4 can be considered protective against IA among the Caucasians, while the CC genotype is predisposing to IA. Th e heterozygous variant CG rs2229910 NTRK3 can be considered protective against IA, and the GG genotype is predisposing to pathological IA among the Caucasian adolescents.
Where emotions are born: how emotional intelligence is formed
Authors:   Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Komleva Yu.K.
Published: October 2022

Emotions play one of the most integral roles in human experience, but it is still considered diffi cult to explain scientifi cally. From an evolutionary perspective, emotions greatly contribute to the ability to survive. If until recently we were talking about an epidemic of aff ective disorders and that they occupy a leading position in the structure of brain diseases, now the situation is aggravated by a dramatic increase in the number of aff ective disorders during the COVID-19 pandemic. In this article, we discuss the anatomical and biochemical basis of emotion formation and how it relates to cognition and emotional intelligence
Drug-induced crystalline nephropathy
Authors:   Russian Medical Academy of Continuous Professional Education, Ostroumova O.D. , Akimova E.S. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Sokolova E.V. ,   Central Clinical Hospital “RZD-Medicine”, Kochetkov A.I. ,   Russian Medical Academy of Continuous Professional Education
Published: October 2022

Drug-induced (DI) crystal nephropathy (CN) is a relatively rare kidney disease that is not always easy to diagnose and potentially leads to acute kidney injury (AKI), which may lead to the need for haemodialysis and is associated with a high risk of mortality. Th e aim of the review was analysis and systematisation of data on drugs, the intake of which is associated with development of DICN, conditioning the increased risk of drug-induced AKI, on its pathophysiological mechanisms, analysis of possible methods of treatment and prevention. The search for the specifi ed keywords was carried out in the eLIBRARY.RU, PubMed®, MEDLINE, EMBASE databases, guidelines and methodological recommendations, materials of databases of adverse reactions, instructions for the medical use of drugs published within the period up to June 2021. Most often, DICN is associated with the use of such drugs as sulfadiazine, acyclovir, indinavir, triamterene, methotrexate, as well as orlistat, ciprofl oxacin, amoxicillin, oral sodium phosphate preparations, etc. Th e main pathophysiological mechanism of CN development is the precipitation of poorly soluble substances in the urine and formation of crystals. Th ereat, one part of the drug crystallises and the precipitate falls out directly into the renal tubules, the other part acts through a change in metabolism, increasing the concentration of other poorly soluble compounds in the urine. The risk factors for DICN include the risk factors for AKI as well as drug-specifi c risk factors, such as urine pH. Clinically, СN is most oft en manifested by symptoms of AKI, sometimes with development of acute renal colic and hematuria. In СN treatment, it is required to cancel the inducer drug or reduce its dose, stimulate diuresis with replenishment of the intravascular fluid volume using infusions of balanced electrolyte solutions. For the prevention of DICN, it is important to take into account all possible risk factors for its development, use adequate doses of drugs and avoid the prescription of potentially nephrotoxic drugs
Clinical and epidemiological features in haemorrhagic fever with renal syndrome in Zabaikalsky Krai
Authors:   Chita State Medical Academy, Kalinina E.N. , Moshkina A.A. ,   «Chita Anti-Plague Station» of Rospotrebnadzor (Federal Service for Consumer Rights Protection and Human Welfare), Moshkin A.B. ,   «Chita Anti-Plague Station» of Rospotrebnadzor (Federal Service for Consumer Rights Protection and Human Welfare), Epiphantseva N.V. ,   Chita State Medical Academy
Published: October 2022

Haemorrhagic fever with renal syndrome (HFRS) is a natural focal zoonotic infection endemic to certain regions of the Russian Federation. Lack of experience and alertness among clinicians in diagnosing this infection, given the absence of active natural foci in Zabaikalsky Krai and the polymorphism of clinical manifestations, led to diagnostic errors and misdiagnoses. A total of six patients (male) from the same epidemic focus area (a shift camp in a forest area) were diagnosed with acute respiratory disease, pneumonia, pleurisy and pyelonephritis when they sought medical help between September and November. The diseases were mild to moderate and characterised by fever, intoxication, cathartic-respiratory and haemorrhagic manifestations, lung damage and decreased diuresis. Th e correct diagnosis of HFRS was only established through retrospective epidemiological analysis using the serological method. Due to clinical thinking and certain alertness to HFRS, the correct diagnosis was only established for two patients. The second case ended being fatal due to rapid development of a severe complication. Comprehensive analysis of the clinical and epidemiological data of the cases presented in the paper enables the clinicians to perform provisional diagnosis correctly and to administer the necessary laboratory tests in order to confirm the diagnosis of HFRS
Seroprevalence Brucellosis in Etawah Crossbreed goat in District Siliragung, Banyuwangi
Authors: Saputro Amung Logam , Praja Ratih Novita , Yudhana Aditya , Mumtazi Fauzan , Romadhona Ma'rifatunnisa' , Anastasya Anastasya , Farhan Muhammad Riesta
Published: October 2022

Brucellosis is a zoonotic bacterial disease that is endemic in many countries, especially developing countries such as Indonesia. Livestock centers in Indonesia have not been free from Brucellosis disease, which reaches 40% and spread almost throughout Indonesia. This study aimed to detect the presence of Brucellosis antibodies in Etawah Crossbreed at Siliragung District, Banyuwangi using the Rose Bengal Test (RBT) method. The data that will be obtained later was expected to provide benefits in reducing the possibility of Brucellosis spread and can be used as a reference for Brucellosis control programs in goats. The results showed that the RBT examination in the sample population of Etawah Crossbreed in Siliragung District which was taken showed negative results in all samples. The conclusion of this study was that Brucella abortus antibodies were not found in Etawah Crossbreed in Siliragung District, Banyuwangi.
Cestode Infection in the Digestive Tract of Ducks from Chicken Slaughterhouses in Bojong Gede and Cibinong Market, Bogor, West Java
Authors: Aviola Lala , Tiuria Risa , Nugraha Arifin Budiman
Published: October 2022

Helminthiasis is a crucial gastrointestinal endoparasitic in ducks. This study aimed to determine the type and degree of infection of adult worms in the digestive tract of ducks at a chicken slaughterhouse in Bogor Regency, West Java. A total of 10 samples of the digestive tract of ducks were collected in this study. Five ducks were collected from a chicken slaughterhouse in Bojong Gede District and five other ducks were collected from a market in Cibinong City. Each intestinal sample was divided into 4 parts, i.e. the duodenum, jejunum, ileum and cecum. Adult cestode worms were stained with Semichon's Acetocarmine for identification. In result, three ducks were positive for endoparasite infection. The cestodes found were Raillietina cesticillus with 20% degree of infection in the jenjunum and ileum respectively. Hymenolepis nana with 20% degree of infection in the jejunum and ileum respectively. Choanotaenia infundibulum with 10% degree of infection in the ileum.
Stall Sanitation Associated with Cryptosporidium sp. Infection on Calf and Cattle Farmer
Authors: Ramadhani Rafindra , Nurdian Yudha , Rachmawati Dwita Aryadina , Utami Wiwien Sugih , Armiyanti Yunita , Hermansyah Bagus , Rahardjo Angga Mardro
Published: October 2022

Increasing the cattle population can increase the amount of the waste. Poor management of cage sanitation has the risk of causing a decrease in the health conditions of cattle farmers, such as: diarrhea, nausea, vomiting, and itching, as many as 50% of cattle with diarrhea are infected with Cryptosporidium sp. The highest infection of Cryptosporidium sp. in cattle found in calves. The calf can excrete 1×1010 oocysts of Cryptosporidium sp. per day. Cryptosporidium sp. also has the potential to cause zoonotic infections that are transmitted from animals to humans. The study aims was to determine the relationship between stall sanitation and Cryptosporidium sp. to calf and cattle farmer. The type of this research was analytic observational with a cross sectional approach conducted in Jatian Village, Pakusari, Jember during October 2021 - March 2022. The primary data was obtained through interviews and observations. The feces of calves and cattle farmer were collected and examined using sedimentation method and modified Ziehl-Neelsen (MZN) staining method. The statistical test used is the chi-square test. The results showed that the prevalence of Cryptosporidium sp. in calves by 14,3% and on cattle farmer by 4,8%. The bivariate analysis showed that that stall location and waste handling were associated with Cryptosporidium for calf (p≤0.05), and there were no variables that were significantly related to infection in cattle farmers (p>0,05). Cryptosporidium sp. in calves and humans can be caused by several factors, such as environmental factors and hosts. Preventive measures such as maintaining a clean environment including cowshed sanitation and personal hygiene need to be taken to reduce the risk of Cryptosporidium infection from calves to humans, and vice versa.
Effect of Combination of Probiotics and Moringa oleifera Leaf Extract on Nutrients Intake in Ducks
Authors: Lokapirnasari Widya Paramita , Al Arif Mohammad Anam , Maslachah Lilik , Chandra Evania Haris , Utomo Gogik Satrio Margo , Yulianto Andreas Berny
Published: October 2022

The purpose of this research was to determine the effect of combination probiotics and Moringa oleifera (M. oleifera) extract in nutrient consumption of ducks. This study used 48 Peking ducks. The concentration of probiotic was 1.2 x 108 CFU/ml. The treatments of this research were P0 (control), P1 (4 ml probiotics), P2 (4 ml M. oleifera extract) and P3 (2 ml probiotics + 2 ml M. oleifera extract). The data were statistically analyzed by Analysis of Variance (ANOVA). The results showed that feed consumption of dry matter, organic matter, crude protein, crude fat, crude fiber and nitrogen free extract were no significant difference (p>0.05) between all treatments. It can be concluded that the addition of combination probiotics and M. oleifera extract can be used to maintain nutrient consumption and safe for health ducks.
Clinical Signs and Haematology Profiles of Beagle Dogs with Tick Infestation
Authors: Mihardi Arief Purwo , Joesoef Jayusman Ayu , Wolo Kathirina Beathrik Riwu , Esfandiari Anita , Widhyari Sus Derthi , Wulansari Retno , Wijaya Agus , Maylina Leni
Published: October 2022

Rhipicephalus sanguineus is one of the vectors that could induce diseases in dogs. A physical examination and haematology test could examine the dog's condition with tick infestation. Five dogs, beagle breeds from Veterinary Teaching Hospital, School of Veterinary Medicine and Biosciences, IPB University, have been examined for physical examination and CBC test. A haematology test was performed using a haematology analyzer and made the blood smear. Physical examination showed that 60% of dogs have a tick infestation, 80% have pallor, 60% have pruritus, 40% have crusted skin, and 100% have wounds in extremities. However, the body temperature and heart rate were relatively normal. Complete blood count test showed that red blood cells (RBC), peak cells volume, and haemoglobin (Hb) decreased (80%), MCHC increased (40%), thrombocytopenia (100%), leukopenia (40%), lymphocytopenia (60%), neutropenia (10%) and monositopenia (80%). The blood smear result showed all dogs have positive blood parasites, with the highest percentage being the third dog (0.056%). From the physical examination, CBC, and blood smear, it can be concluded that dogs with tick infestation would experience anaemia that showed by RBC, PCV, decreasing number of platelet and positive blood parasite.
Rationale for haploinsufficiency correction therapy in neurofibromatosis type 1
Authors: Frost Michael , Serra Eduard , Viskochil David , Korf Bruce R. , Mattson-Hoss Michelle K. , Croston Glenn E. , Sarnoff Herb
Published: October 2022

Neurofibromatosis type 1 (NF1) is a genetic disorder with a wide range of manifestations and severity. Currently, the few available NF1 treatments target specific manifestations, with no available therapies targeted to correct the underlying driver of all NF1 manifestations. Evidence supports that haploinsufficiency in NF1 caused by a decreased amount of wild-type (WT) neurofibromin in all Nf1+/- cells directly causes or facilitates a range of NF1 manifestations. Consequently, NF1 haploinsufficiency correction therapy (NF1-HCT) represents a potentially effective approach to treat some NF1 manifestations. NF1-HCT would normalize the level of WT neurofibromin in all NF1-haploinsufficient cells, including those integral to the NF1 phenotype such as Schwann cells (SCs), melanocytes, neurons, bone cells, and cells of the tumor microenvironment. This would correct altered cellular signaling pathways and, in turn, restore normal function to cells with a retained WT allele. NF1-HCT will not restore WT neurofibromin in NF1-/- cells; however, by restoring function in the surrounding Nf1+/- microenvironment cells, NF1-HCT is predicted to have a beneficial effect on NF1-/- cells. NF1-HCT is expected to have a clinical effect in some NF1 manifestations, as follows: (i) prevention, or delay of onset, of potential manifestations; and (ii) reversal, or halting/slowing progression, of established manifestations. This review describes the rationale for NF1-HCT, including specific NF1 considerations (e.g., NF1 clinical phenotype, neurofibromin function/regulation, NF1 mutational spectrum, genotype-phenotype correlation, and the impact of haploinsufficiency in NF1), HCT in other haploinsufficient diseases, potential NF1-HCT drug treatment strategies, and the potential advantages/challenges of NF1-HCT.
Improved sealing polymers and cleaning procedures to mitigate aroma carryover during bottling of aromatised and regular wines on the same filling line
Authors: Gottmann Jörg , Müller David , Becker Anna Maria , Vestner Jochen , Schuster Jens , Fischer Ulrich
Published: October 2022

Bottling of aromatised wines and regular table wines often takes place on the same bottling line. Installed sealings in the bottling line absorb volatiles from aromatised wines and, due to inadequate cleaning, carryover occurs into the subsequently bottled regular wine. This unintentional carryover can lead to accusations of illegal flavouring of wine. To minimise the carryover risk, sealing materials that absorb less volatiles are beneficial. Incorporating kaolin and micro-cellulose into the ethylene propylene diene monomer rubber (EPDM) network decreased absorption of the critical α-ionone by 51 and 60 %, respectively.Besides the minimisation of the absorption, a performed cleaning can reduce aroma carryover. So far, knowledge about cleaning parameters that can increase cleaning efficiency is limited since cleaning usually focuses on surficial removal and prevents microbiological cross-contamination. An evaluation of the cleaning parameters, temperature, time and agents clearly revealed a high factor in the considered temperature. The highest cleaning efficiency was seen at 85 °C, whereas the cleaning additives such as citric acid, caustic soda, ozone or dissolved carbon dioxide had no impact. High proportions of the aroma compounds were removed from the polymer in the first 20 min at 85 °C, but none of the performed cleaning sequences was able to remove all compounds.