bluuebunny/crossref_metadata_2025 huggingface dataset:
Muntingia calabura: A comprehensive review
Authors: Kuchekar Mohini , Upadhye Mohini , Pujari Rohini , Kadam Shailja , Gunjal Priya
Published: November 2021

Medicinal plants are well-known sources of important therapeutic aid for alleviate human disorders. (Elaeocarpaceae) is the widely used in the ayurvedic system of the medicine as very sweet, musky, fig-like flavour. also known as Jamaica cherry, is a small and evergreen tree. The necessity of plant in human ailments is illustrious in old medicinal practices. The secondary metabolites are obtained from the different parts of plant alkaloids, flavonoids, tannin, phenolic compound etc. are traditional medicinal uses have been reported for the leaves (headaches, prostate problems, reduce gastric ulcers), bark (antiseptic), flowers (antiseptic, reduce swelling, antispasmodic), and fruits (respiratory problems, antidiarrheic). The present study gives an overview on plant and its pharmacological activities were documented.
Vade-mecum drogami cnoty. O poetyckiej aretologii Cypriana Norwida
Authors: Ziołowicz Agnieszka
Published: November 2021

Artykuł dotyczy obrazowania i koncepcji cnoty w cyklu poetyckim Vade-mecum. Przedmiot analizy stanowią utwory, w których mamy do czynienia z bezpośrednimi nawiązaniami do tej problematyki (Larwa, Fatum, Ironia, Zawody, Centaury, Królestwo, Cnót-oblicze, Bohater, Ideał i reformy, Fortepian Szopena), jednak widzianymi w kontekście całego dzieła pisarza i sytuowanymi na tle starożytnej, greckiej i rzymskiej, oraz chrześcijańskiej refleksji aretologicznej. Poetycka aretologia Norwida pozostaje w ścisłym związku z wymienionymi tradycjami, podlega również inspiracjom literackim (zwłaszcza Homer, Prudencjusz, Dante), a także artystycznym (ikonografia cnoty). Jak dowodzą przeprowadzone analizy, wątek aretologiczny, obejmujący przede wszystkim refleksję nad takimi cnotami, jak męstwo, umiarkowanie, sprawiedliwość i kalokagathia, jest ważnym czynnikiem spójności Vade-mecum (na poziomie kreacji podmiotu dzieła, w epickiej płaszczyźnie cyklu, w obrębie problematyki antropologiczno- etycznej). Jest to zespół zagadnień pozwalających lepiej zrozumieć Norwidowską koncepcję poety-moralisty oraz Norwidowską diagnozę kryzysu człowieczeństwa w XIX wieku.
Społeczność i historia, czyli pieniądz i krew. Ekonomia w Vade-mecum Norwida
Authors: Gadamska-Serafin Renata
Published: November 2021

Temat pieniądza zajmuje w Vade-mecum poczesne miejsce, proporcjonalnie do pozycji, jaka przypadła finansom i ekonomii w koncepcjach polityczno-społecznych oraz filozoficznych XIX stulecia. Tematyka „kapitałowa” pojawia się między innymi w takich ogniwach cyklu, jak Socjalizm, Larwa, Stolica, Prac-czoło, Syberie, [Co słychać?], Nerwy. Norwidowskie opus magnum kształtowało się w atmosferze wielkiego przesilenia gospodarki kapitalistycznej: kryzysu światowego po wojnie secesyjnej (1866), którego skutki pokazał w pierwszym tomie swego Kapitału (1867) Marks. Słynna publikacja niemieckiego ekonomisty stanowi ważny, choć w sensie ideowym – biegunowo odległy, kontekst Norwidowskiego cyklu. Ważną inspiracją były natomiast dla poety czytane w latach 40. dzieła Proudhona i zapewne innych socjalistów utopijnych (może Owena), proponujące rezygnację z dotychczasowych form pieniądza jako antidotum na kryzysy ekonomiczne i nędzę mas. W liście Norwida z 15 lipca 1867 roku (PW , IX, 297) pojawia się ponadto ślad lektury rozprawy Augusta Cieszkowskiego pt. Du Crédit, et de la Circulation (Paris 1839) oraz dowód kontaktów autora Vade-mecum z ekonomistą Ludwikiem Wołowskim, współzałożycielem i dyrektorem paryskiego banku Crédit Foncier de France (zał. w r. 1852), którzy przenieśli do Francji Napoleona III genialne pomysły kredytowe księcia Druckiego-Lubeckiego. Norwid podejmuje w Vade-mecum polemikę zarówno z utopijnymi pomysłami socjalistycznej gospodarki bezpieniężnej, jak i z polskimi koncepcjami organicystycznymi, osadzonymi na ekonomii zysku i wizji sukcesu gospodarczego. Dostrzega ich oderwanie od Dekalogu, kategorii „sumienia” i chrześcijańskiej soteriologii. Vade-mecum staje się próbą (romantyczną i chrześcijańską) przywrócenia spraw pieniężnych do ich pierwotnego kontekstu: idealnego i duchowego.
Michał Kleczkowski – kuzyna żywot paralelny
Authors: Zemanek Bogdan
Published: November 2021

Michał Kleczkowski, kuzyn Cypriana Norwida, wybrał nietypową karierę sinologa. Jako zawodowy tłumacz i dyplomata w służbie francuskiej, osiągnął ostatecznie stanowisko chargé d’affaires, a po powrocie z długoletniej (1847-63) służby w Chinach – konsula generalnego ds Chin, a następnie profesora języka chińskiego w École nationale des langues orientales vivantes, którym był lat dwanaście. Reprezentował nowy typ dyplomaty-profesjonalisty, a choć korzystał ze wsparcia wpływowych osób, karierę zrobił głównie dzięki pracowitości i zaangażowaniu. Postawa profesjonalisty i prawdopodobnie dość konwencjonalna moralność powodowały napięcia w jego stosunkach z Norwidem, wyznającym nader odmienny ideał wolnego artysty, niegodzącego się na rzemieślniczą pracę na cudzych warunkach. Artykuł próbuje równoważyć dotąd negatywną ocenę postawy Kleczkowskiego wobec Norwida, wskazując na fakt, że kuzyn poety wspierał go finansowo przez 12 lat, przeznaczając na to znaczący odsetek własnych dochodów; dyskutuje też kwestię statusu Domu Św. Kazimierza, jako godnej szacunku instytucji, zapewniającej swym podopiecznym stosunkowo godny byt, zwłaszcza w porównaniu z warunkami, na które skazani byli niemający wsparcia paryscy ubodzy. Tezy artykułu są ilustrowane korespondencją Kleczkowskiego zachowaną w Muzeum Czartoryskich w Krakowie.
Vade-mecum w perspektywie czasu Zarys problematyki
Authors: Fert Józef Franciszek
Published: November 2021

W artykule dotknięty został istotny kompleks ideowy i artystyczny całej twórczości autora Vade- mecum. To ujęcie czasu w relacji do ruchu, które zaprząta zresztą filozofów, poetów i uczonych od starożytności do dziś, przynosząc po drodze m.in. genialną koncepcję Alfreda Einsteina, dającą się zamknąć w eleganckiej kategorii czasoprzestrzeni, a równocześnie prowadząc dalej – do teorii strun, teorii wielowymiarowości czy wreszcie teorii nieprzemienności. Po stronie poezji mamy mit „wiecznego powrotu”, genialne tragedie starożytnych Greków, Szekspirowskie udramatyzowanie losów ludzkich poprzez bieg w czasie nieuchronnych następstw paktowania ze złem (jak w Makbecie), przejmującą reinterpretację Pasji Jezusa w Mickiewiczowskiej psychomachii, czyli Dziadów części trzeciej, apokaliptyczną wizyjność Krasińskiego Nie-Boskiej komedii i zanurzenie w problematyce (nierzadko alegoryzowanej) przełomu dziejów, jaką przynosi Norwidowski Quidam, dziejący się „pomiędzy świtem a nocy zniknięciem...”. Po stronie filozofii wspomnijmy Hegla, który „kazał logicznie” zamknąć się dziejom w jego genialnej myśli jako szczycie i finale procesów historycznych...
Obrazy dziania się – ruchu w czasie – mają u Norwida zwykle dramatyczne zakotwiczenie w następstwie zdarzeń lub w konsekwencji wnioskowania z przywołanych przesłanek („ruch myśli”). Znamienne są tu perspektywy nie tyle bliżej nieokreślonej przemiany jako efektu anonimowego procesu, co raczej docieranie do jakichś konsekwencji „dziania się”, która w poetyckim ujęciu przybiera nierzadko kształt zaskakującej puenty będącej zarazem ukrytą lub jawna „nauka moralną”, niekiedy na skutek nadprzyrodzonej interwencji, jak w wierszu XIV. Litość, w którym ciąg pozornych czy konwencjonalnych znaków współczucia przerywa „grom z jasnego nieba”, zmuszając do autentycznej pomocy bliźniemu.
Warto pamiętać, że Vade-mecum w znacznym stopniu, jeśli nie w istocie, to z jednej strony dzieło programowe, ale z drugiej – autentyczny wybór autorski z twórczości poetyckiej z lat 1848–1866, poddany określonej funkcji programowej, w której problem zobowiązań moralnych wysuwa się na plan pierwszy jako odpowiedź poetycka na istotne zapotrzebowanie chwili bieżącej jako czyn artystyczny mający służyć swoim czasom. Stąd tak ogromne poczucie niespełnienia, jakiego doświadczał Norwid jako „nadkompletowy aktor” w tym teatrze wieku, mówiąc słowami Zofii Stefanowskiej, „kupieckiego i przemysłowego”.
Czystość Lorda Singelworth
Authors: Pniewski Dariusz
Published: November 2021

W artykule poddano analizie postać głównego bohatera Tajemnicy Lorda Singelworth z perspektywy XIX-wiecznej imagologii. Z tej analizy wynika, że postać została skonstruowana z rozpowszechnionych w ówczesnej Europie stereotypów na temat Brytyjczyków. Tłumaczą one dziwactwa Singelwortha: latanie balonem, obsesję czystości. Wyjaśniają również, dlaczego większość obserwatorów balonowej pasji lorda zgodnie przyjmowała zaskakujące jej wyjaśnienie – pragnienie uregulowania kłopotów gastrycznych. Uzupełnia ten zestaw charakterystyczna wyniosłość, moralna motywacja działań, poczucie misji i eskapizm. Autor tekstu stawia tezę, że tak skonstruowana figura Anglika, umiejscowiona w Wenecji u progu historycznych zmian mogła być literackim autoportretem Norwida.
DEPENDENCE OF MAXIMAL SENSITIVITY OF THE MAGNETIC FIELD HALL SENSORS BASED ON GRAPHENE ON TEMPERATURE
Authors: Bolshakova І. , Strikha М. , Kost Ya. , Shurygin F. , Mykhashchuk Yu. , Wang Z. , Neumaier D.
Published: November 2021

A theory of graphene-based magnetic field Hall sensors sensitivity dependence on temperature is summarized. The existence of low-temperature range with sensitivity, almost independent on temperature, is predicted; at higher temperatures, when thermally-induced carrier concentration in graphene prevails, the sensitivity decreases with temperature. The experimental studies of the temperature dependence of magnetic sensitivity of Hall sensors on single layer graphene base were carried in temperature range from 300 °K to 430 °K. The values of sensitivity, obtained for room temperatures ~ 230 V·А‑1·Т‑1 exceed essentially the maximum sensitivity of the traditional Hall sensors on silicon base ~ 100  V·А‑1·Т‑1.
Effect of INM Practices on the Leaves Parameters of Terminalia tomentosa Food Plant of Antheraea mylitta Drury
Authors: Karmakar Soma , Srivastava A.K. , Pandiaraj T. , Tirkey Jyostna
Published: November 2021

Background: Terminalia tomentosa is a primary food plant of Antheraea mylitta Drury a polyphagous insect of Saturniidae family which is exploited commercially for the production of silk. Good quality of silk production depend on the nutrient of leaf. So, to optimize the nutrient of leaf integrated nutrient management practices has been used to increase soil fertility and to supply plant nutrient at an optimum. Methods: In order to evaluate the effect of INM practices on the leaves parameters of Terminalia tomentosa food plant of Antheraea mylitta Drury. An experiment based on randomised complete block design with 21 treatments and three replication was conducted at Central Tasar Research and Training Institute, Nagri, Ranchi in the year 2019-20. Result: Results revealed that the application of INM treatments are significant on various leaf parameters. Highest single leaf length and breadth mean was observed in T19 (23.29 cm; 11.96 cm) was applied with 75% RDF through fertilizer+25% through vermicompost+ Azotobacter + PSB, weight of single leaf was found to be highest in T13 (5.19 g). The number of leaf was recorded highest in T19 (1892). The fresh leave yield ranged from 1617.317-5208.224 g with average mean of 4085.72 g, T19 (5032.1 g) recorded the highest fresh leaf yield. The dry matter content was found highest in T19 (340.56 g). The moisture content was recorded higher in T4 (71%) followed by T15 (69%).
Protocol Optimization for Rapid Multiplication of Cassava (Manihot esculenta Crantz) using the Nodal Segment
Authors: Feyisa Ashebir Seyoum
Published: November 2021

Background: Cassava is a vital food security crop for millions of people, especially in sub-Saharan Africa. Since the crop produces a reasonable yield on marginal soils, it could help alleviate world hunger. Consequently, the increase in cassava production and its quality characteristics are significant. However, the low multiplication rate of this main crop has delayed the spread of improved varieties among farmers. As a result, tissue culture techniques can be a viable solution to overcome these challenges. Methods: The study used a nodal segment as an explant to evaluate different concentrations of BAP and NAA for an efficient, cost-effective in vitro mass multiplication of the AWC-1 cassava variety. CuSO4, commercial bleach and ethanol had used to sterilize nodal explants taken from greenhouse-grown plants at various time intervals. Result: The best medium for micro shoots induction had found to be medium without growth regulators. Among different treatments used for shoot multiplication purposes, the maximum shoot number has been recorded on M.S. medium supplemented with 0.75 mg/l BAP and 0.2 mg/l NAA. Medium with 0.5 mg/l NAA concentration was the best for rooting induction. A survival rate of 86% has obtained in the greenhouse and the plantlets appeared to be morphologically normal.
Effect of Conditioning Methods on Mechanical Properties of Raw Bael Fruit
Authors: Sahu Indrajeet , Rayaguru Kalpana , Pattnaik Rashmi Ranjan , Dash Sanjaya Kumar
Published: November 2021

Background: Bael is an important indigenous fruit, which is rich in nutritional and health promoting factors. Development of value-added products from this fruit poses a problem as the fruit has a hard rind and is difficult to be removed by hand. Methods: The objective of this investigation was to evaluate the effect of different conditioning methods as normal water dipping (25-27°C), chilling (10-11°C), freezing (4-5°C) and hot water dipping (90-95°C) on firmness and other mechanical properties of raw and matured bael fruit, with a goal of devising some methods for easy removal of the rind. The fruits after conditioning were subjected to puncture test by universal testing machine. Distinct peaks were observed on the force-displacement traces which indicated the rupture force and firmness of the fruits. The changes observed in rupture force, deformation and firmness in conditioned samples were compared. Result: Rupture force measured for control sample (kept under ambient conditions) was 344.4±27.13 N and was found to be lower than that of the conditioned samples. The minimum rupture force of 192.6±14.41 N was observed in frozen sample. No significant difference in rupture force could be observed between the normal water dipped sample and chilled samples. Hot water dipped sample required a rupture force of 215.3±29.2 N, which was not significantly (p greater than 0.05) less than those of other treatments but, the green color of the fruits degraded to brown. The change in other mechanical properties also remained similar. The results would be useful for preparing the raw bael fruit for further processing and value addition.
Radiographic Changes vis-à-vis Tracheo-bronchial Aspirate Cytology Profile in Pneumonic Cattle
Authors: Narang Asmita , Singh Charanjit , Anand Arun , Randhawa Swaran Singh
Published: November 2021

Background: The study was conducted to establish the utility of radiography in the diagnosis of lung diseases in cattle and its correlation with different pneumonia diagnosed on the basis of TBA cytology. Methods: Lateral chest radiography and tracheo-bronchial wash was performed in control (n=21) and diseased group (n=55). Diseased group included cattle presented with respiratory signs and diagnosed with pulmonary diseases on the basis of history, physical and clinical examination and tracheo-bronchial wash cytology. Cytologic diagnosis was established as chronic pneumonia (n=24), acute pneumonia (n=18), tuberculosis (n=5) and aspiration pneumonia (n=8). Survivability was also correlated with lung patterns in diseased cattle. Result: Nodular interstitial pattern (27.3%), unstructured interstitial pattern (25.4%), bronchial pattern (20.0%), pleural effusions (12.7%), mixed lung patterns (10.9%) and miliary interstitial pattern (4.54%) was observed in diseased group. Unstructured interstitial pattern and pleural effusions were most evident in acute pneumonia. The radiographic findings in aspiration pneumonia did not correlate well with cytologic findings. Highest survivability was recorded in cows with bronchial pattern (81.8%) and lowest in miliary interstitial pattern (zero per cent).
Rehabilitation of an Internet network in 40 schools in Nabón, Ecuador
Authors: Cabrera-Tituana Ronny Israel , Carrión-Herrera Andrea Katherine
Published: November 2021

Internet access is necessary to ensure respect for the right to education, however, worldwide about 75% of school-age children in rural areas do not have access to the Internet at home, which makes it imperative the need for actions to reduce the digital gap to improve the quality of education in rural communities in Ecuador. This article describes the rehabilitation of an Internet network of 40 schools in the Nabón community, Ecuador. An earlier initiative implemented the Internet network, but lack of maintenance left it non-functional. With the support of the Municipality of Nabón, Motorola Foundation and IEEE SIGHT, a group of volunteers from IEEE Ecuador evaluated the state of the network to identify opportunities using the existing infrastructure. The commitment to the community, as well as the development of capacities, are at the center of the intervention to guarantee the sustainable development of the project. This document reports on the design, implementation, achievements and lessons learned from the rehabilitation of the Internet network.
The Impact of Economic Shocks on Workers' Labor Market Outcomes
Authors:   , Illing Hannah
Published: November 2021

In this dissertation, I analyze the effect of economic shocks on workers' labor market outcomes. In the first part of this thesis (Chapter 2), I investigate a labor supply shock in the form of cross-border migration. Chapters 3 and 4 in the second part of this thesis focus on the labor market impact of job displacement, resulting from a mass layoff, on individual workers’ careers.
Neoliberalismo, educação e capital humano
Authors: Leite Larissa Maciel , Raimundo Lício da Costa
Published: November 2021

O artigo busca inicialmente entender os contornos e contextos que condicionaram a construção do sujeito neoliberal nas sociedades capitalistas contemporâneas, o qual é constantemente moldado pela razão neoliberal a fim de atender as expectativas do mercado e garantir que as engrenagens desse sistema continuem em funcionamento. Após esclarecer a constituição desse neossujeito, o artigo também busca entender o papel da educação nesse processo de manutenção do status quo a partir de sua subordinação à lógica empresarial de acumulação e reprodução do capital. A argumentação se completa com considerações sobre a seguinte pergunta: A lógica neoliberal que rege o capitalismo contemporâneo é uma ameaça à democracia?
Em qual região do Brasil os corredores apresentam o melhor desempenho?
Authors: Thuany Mabliny , Gomes Thayse Natacha
Published: November 2021

O crescimento no número de praticantes de corrida de rua tem sido evidenciado ao longo das últimas décadas, assim como o número de eventos da modalidade, e a mobilidade de corredores pelo país para participar destes eventos. A proposta do presente estudo foi verificar se há diferenças no desempenho de corredores de rua brasileiros, consoante região de residência, bem como investigar se a região pode ser considerada um preditor de performance em corredores de ambos os sexos. A amostra foi composta por 1158 corredores de rua, de ambos os sexos (39,6% mulheres; 60,4% homens), oriundos de todas as regiões do país. A obtenção dos dados ocorreu a partir do envio de um questionário online, onde foram obtidas informações a respeito do sexo, idade, massa corporal (kg), altura (m), volume de corrida/semana (km), ritmo de corrida (seg/km) e região de residência. Teste Kruskal-Wallis (H), seguido do teste U-man Whitney (U), foram computados para identificar diferenças no ritmo de corrida entre as regiões brasileiras, consoante sexo. Em seguida, realizou-se análise de regressão robusta, com ajuste para a idade, para verificar associação entre a região de residência com a performance, tendo a região Sul como referência, considerando p<0,05. Verificaram-se diferenças significativas na média do ritmo de corrida entre as mulheres das cinco regiões (H=25,52; p <0,001), sendo que aquelas oriundas da região Sul apresentaram melhor desempenho do que seus pares das regiões Sudeste (U=60,9; p=0,016), Norte (U=26,7; p=0,027), Centro-Oeste (U=25,3; p=0,004), Nordeste (U=93,9; p<0,001).  Exceção para a região Norte, corredoras residentes em outras regiões do país experimentam redução da performance comparativamente às da região Sul. A maior redução na performance foi verificada para atletas residentes na região centro-oeste (b=49,1; IC95%= 20,3 – 77,8). Para o sexo masculino, verificou-se associação significativa e inversa entre atletas residentes na região Nordeste e o desempenho, com aumento de ≈17 segundos por quilômetro (b=17,1; IC95%= 2,9 – 31,4). Corredores de rua residentes na região Sul do país apresentaram performance superior a seus pares, para ambos os sexos. Tais resultados podem reforçar a importância da realização de eventos e existência de apoio à modalidade nas demais regiões.
Excesso de peso em adolescentes de um município de Minas Gerais em 2019 e 2020
Authors: Flores Bicalho Juliana Mara , De Souza Borges Neto Juscelino , Gonçalves Gomes Tulio , Da Silva Cruz Ana Caroline , Sthefany Tavares Isabella
Published: November 2021

Adolescência, período dos 10 aos 19 anos, é uma fase caracterizada por transformações biopsicossociais como modificações de peso, estatura, composição corporal, transformações fisiológicas nos órgãos internos e crescimento ósseo. Avaliação do estado nutricional tem por objetivo verificar o crescimento e proporções corporais estabelecendo atitudes de intervenção. Adolescentes têm sido considerados de risco nutricional em razão de seus hábitos alimentares, pois por vezes deixam de fazer refeições saudáveis substituindo-as por lanches de baixo valor nutritivo, este fato parece ter se agravado na Pandemia COVID-19. Objetivo: Apresentar o estado nutricional de adolescentes acompanhados na Atenção Primária à Saúde através do Sistema de Vigilância Alimentar e Nutricional - SISVAN em 2019 e 2020, anos antes e após o início da Pandemia COVID-2019. Metodologia: Trata-se de um estudo descritivo. Para a classificação do estado nutricional de adolescentes foi adotado referência da Organização Mundial da Saúde e utilizado o Índice de Massa Corporal. Resultados: Em 2019 foram registrados acompanhamentos de 1892 adolescentes no SISVAN, o que representa 5,5% dos adolescentes do município. Naquele ano 26,90% apresentavam excesso de peso. Já em 2020, ano do início da Pandemia de COVID-19, foram registrados acompanhamento de 2163 adolescentes, o que representa 5,5% dos adolescentes do município. Neste ano 33,94% dos adolescentes acompanhados apresentaram excesso de peso de acordo com IMC para idade, o que representa um aumento de 26,17%.  Conclusão: É importante o registro do estado nutricional de adolescentes no SISVAN para um melhor diagnóstico da prevalência de excesso de peso, especialmente obesidade, a fim de conhecer o quadro real deste problema no município, principalmente durante e após a Pandemia COVID-19. O excesso de peso é um problema grave e prevalente nos adolescentes, sendo necessárias novas práticas de intervenções efetivas relacionadas à alimentação saudável e à prática de exercício físico para que se mude este cenário.
The Convention on Older Person's Rights: A Graphic Guide
Authors:   University of Dundee, Crowe Mayra , Berriel Fernando , Rovira Adriana , Torena Denisse , Nero Monty , Herd Damon
Published: November 2021

This comic was created through an international partnership between the Centro lnterdisciplinario de Envejecimiento. Universidad de la Republica of Uruguay and the Scottish Centre for Comics Studies. University of Dundee. In June 2015 the Organisation of American States (OAS) signed the Inter-American Convention of Protecting the Human Rights of Older Persons. In order to encourage the implementation of this invaluable legal instrument. It is paramount to promote its ratification in those countries that have not done so. The creation of Monitoring Steering Committee requires a minimum of 10 countries to ratify the Convention. As of September 2021, only 8 Member States have ratified it. This comic presents an overview of the Convention. Its aim is to inform and create awareness of the benefits of ratification amongst stakeholders and the general population. This comic is dedicated to yesterday’s, today’s, and tomorrow’s older population.
Ten Simple Rules for FAIR Sharing of Experimental and Clinical Data with the Modeling Community
Authors: König Matthias , Grzegorzewski Jan , Golebiewski Martin , Hermjakob Henning , Hucka Mike , Olivier Brett , Keating Sarah , Nickerson David , Schreiber Falk , Sheriff Rahuman , Waltemath Dagmar
Published: November 2021

Science continues to become more interdisciplinary and to involve increasingly complex data sets. Many projects in the biomedical and health-related sciences follow or aim to follow the principles of FAIR data sharing, which has been demonstrated to foster collaboration, to lead to better research outcomes, and to help ensure reproducibility of results. Data generated in the course of biomedical and health research present specific challenges for FAIR sharing in the sense that they are heterogeneous and highly sensitive to context and the needs of protection and privacy. Data sharing must respect these features without impeding timely dissemination of results, so that they can contribute to time-critical advances in medical therapy and treatment. Modeling and simulation of biomedical processes have become established tools, and a global community has been developing algorithms, methodologies, and standards for applying biomedical simulation models in clinical research. However, it can be difficult for clinician scientists to follow the specific rules and recommendations for FAIR data sharing within this domain. We seek to clarify the standard workflow for sharing experimental and clinical data with the simulation modeling community. By following these recommendations, data sharing will be improved, collaborations will become more effective, and the FAIR publication and subsequent reuse of data will become possible at the level of quality necessary to support biomedical and health-related sciences.
Developing Community Disaster Resilience in Lembang Fault Area, Indonesia: Lessons Learned from Japanese Experience
Authors: Abdulharis Rizqi , Handayani Alfita Puspa , Isouchi Chikako , Meilano Irwan
Published: November 2021

Having experienced large-scale disasters between 2004 and 2006, the fatalities due to large-scale disasters in 2018 were still high. In contrast, disaster risk management (DRM) and CDR in Japan have been continuously improved. Thus, there is a need to develop CDR for supporting DRM in Indonesia by learning from the Japanese experience, particularly in a disaster-prone area without large-scale disaster experience. This research was a pilot project on the development of CDR in Indonesia. The case study was a geological hazard-prone Lembang Fault area. People’s perception was collected using structured interviews, while demographic and local economic data was acquired from official statistical publications. Satellite imageries were utilized to acquire natural and built environment and land use/land cover and their changes between 2019 and 2021. Although the degrees of social capital, risk knowledge including indigenous knowledge and past disaster experience were high, government interventions on DRM and land administration are required to develop CDR in Lembang Fault area. Organized community development is expected rather than to solely involve NGOs. Moreover, strategies to develop economic resilience are needed to allow the community to bounce back from future disaster. Finally, a detail baseline data should be collected to develop DRM strategy and CDR.
Kirchhoff-Love Plate Theory: First-Order Analysis, Second-Order Analysis, Plate Buckling Analysis, and Vibration Analysis Using the Finite Difference Method
Authors: Fogang Valentin
Published: November 2021

This paper presents an approach to the Kirchhoff-Love plate theory (KLPT) using the finite difference method (FDM). The KLPT covers the case of small deflections, and shear deformations are not considered. The FDM is an approximate method for solving problems described with differential equations. The FDM does not involve solving differential equations; equations are formulated with values at selected points of the structure. Generally in the case of KLPT, the finite difference approximations are derived based on the fourth-order polynomial hypothesis (FOPH) and second-order polynomial hypothesis (SOPH) for the deflection surface. The FOPH is made for the fourth and third derivative of the deflection surface while the SOPH is made for its second and first derivative; this leads to a 13-point stencil for the governing equation. In addition, the boundary conditions and not the governing equations are applied at the plate edges. In this paper, the FOPH was made for all of the derivatives of the deflection surface; this led to a 25-point stencil for the governing equation. Furthermore, additional nodes were introduced at plate edges and at positions of discontinuity (continuous supports/hinges, incorporated beams, stiffeners, brutal change of stiffness, etc.), the number of additional nodes corresponding to the number of boundary conditions at the node of interest. The introduction of additional nodes allowed us to apply the governing equations at the plate edges and to satisfy the boundary and continuity conditions. First-order analysis, second-order analysis, buckling analysis, and vibration analysis of plates were conducted with this model. Moreover, plates of varying thickness and plates with stiffeners were analyzed. Finally, a direct time integration method (DTIM) was presented. The FDM-based DTIM enabled the analysis of forced vibration of structures, with damping taken into account. In first-order, second-order, buckling, and vibration analyses of rectangular plates, the results obtained in this paper were in good agreement with those of well-established methods, and the accuracy was increased through a grid refinement.
A Prebiotic Ribosylation of Pyrimidine Nucleobases Promoted by Metal Cations and Clay Minerals
Authors: Chen Qian-Qian , Zhao Ze-Run , Wang Xiao
Published: November 2021

We report a prebiotically relevant solution to the N1-ribosylation of pyrimidine nucleobases, a well-known challenge in the RNA World hypothesis. It is found that the presence of metal cations and clay mineral enables the previously unachievable direct ribosylation of uracil, providing by far the highest yield. Spectroscopy and chromatography analyses confirmed the formation of ribosylated uracil. The method can also be extended to the ribosylation of 2-pyrimidinone. These findings are also compatible with the metal-doped-clay model developed by our lab for the unified route of the selection of ribose and subsequent syntheses of nucleotide and RNA.
Fabrication Methods for Integrating 2D Materials
Authors: Moss David
Published: November 2021

With compact footprint, low energy consumption, high scalability, and mass producibility, chip-scale integrated devices are an indispensable part of modern technological change and development. Recent advances in two-dimensional (2D) layered materials with their unique structures and distinctive properties have motivated their on-chip integration, yielding a variety of functional devices with superior performance and new features. To realize integrated devices incorporating 2D materials, it requires a diverse range of device fabrication techniques, which are of fundamental importance to achieve good performance and high reproducibility. This paper reviews the state-of-art fabrication techniques for the on-chip integration of 2D materials. First, an overview of the material properties and on-chip applications of 2D materials is provided. Second, different approaches used for integrating 2D materials on chips are comprehensively reviewed, which are categorized into material synthesis, on-chip transfer, film patterning, and property tuning / modification. Third, the methods for integrating 2D van der Waals heterostructures are also discussed and summarized. Finally, the current challenges and future perspectives are highlighted.
Pedagogical aspects of the formation of professional competence among students of physical culture and sports
Authors: Tkachov Sergij , Liannoi Mykhailo , Shapovalova Olha
Published: November 2021

The main purporse is to determine the main aspects of professional competence among students of physical culture and sports. The pedagogical practice of future physical culture teachers is an integrating and core component of the personal and professional formation of a future specialist, which provides for the formation of his professional competence through mastering various types of activity, leads to professional self-improvement, student self-knowledge in various professional roles in the real conditions of a general education school. Among the main tasks facing the system of higher pedagogical education, an important place is occupied by the task of training a competence-based specialist of a wide profile, further strengthening of fundamental education and bringing it closer to research and practical professional activity, therefore, the goal of training should provide for an optimal combination of theoretical knowledge and creative abilities of future teachers, which would allow them, after graduating from an educational institution, to independently raise the level of their education and professional training, to find fundamentally new solutions to the problems of science and practice. The study was carried out using the following theoretical methods: systems analysis and synthesis, induction and deduction, comparison, classification, generalization and systematization, idealization and abstraction. As a result of the study, the main aspects of professional competence among students of physical culture and sports were determined
JACIII Distinguished Editor & Outstanding Reviewer Awards 2021
Authors:   Editorial Office
Published: November 2021

The JACIII Distinguished Editor and Outstanding Reviewer Awards were established for the purpose to honor and editors who have made a significant contribution to the growth of the JACIII in 2018 and to acknowledge reviewers who have made a significant contribution to reviewing in 2019. We express our deepest gratitude for their professional work, which we believe conductive to development of not only the JACIII but also scientific research.

JACIII DISTINGUISHED EDITOR AWARD 2021

Tomomi Hashimoto (Saitama Institute of Technology, Japan) Zhen-Tao Liu (China University of Geosciences, China) Bin Xin (Beijing Institute of Technology, China) Jianqiang Yi (Institute of Automation, Chinese Academy of Sciences, China) Junzo Watada (Waseda University, Japan) Yaping Dai (Beijing Institute of Technology, China) Zhiyang Jia (Beijing Institute of Technology, China) Wentao Gu (Zhejiang Gongshang University, China)
EMPIRICAL STUDIES OF THE EFFECT OF OPERATIONAL COSTS AND OPERATING INCOME, FINANCING TO DEPOSIT RATIO AGAINST RETURN ON ASSET WITH NON-PERFORMING FINANCING AS INTERVENING VARIABLES IN SHARIA BANK INDONESIA 2013-2020
Authors: Apriyanti Rini , Asmak Ab Rahman  , Maharani Shinta
Published: November 2021

Return On Asset is a profitability ratio that can measure the company's ability to produce labs. In this study, the researchers found data on the quarterly financial reports of Bank Syariah Indonesia that the FDR value increases. However, the ROA value and decreased, found the BOPO and NPF values decreased but were not accompanied by an increase in ROA. This study using a quantitative method with an associative approach. The type of data used is secondary data from the 2013 first-quarter financial statements - In the fourth quarter of 2020, data is taken from the Bank Syariah Indonesia website. Data analysis using classical assumption test, simple linear regression analysis, linear regression analysis multiple, hypothesis testing, and path analysis. The results showed that NPF could mediate between BOPO and ROA. NPF can mediate between FDR and ROA. The cause of the decrease in ROA is caused because the BOPO value is still relatively high due to Sharia Bank Indonesia's performance less efficient and have the FDR value in several quarters exceed the maximum limit. So it indicates that the bank is less efficient in the distribution of financing and has an NPF value that exceeds the limit set by Bank Indonesia in several quarters. The solution is to make BOPO efficient. Indonesian Sharia Banks must pay attention to operational efficiency by paying attention to costs incurred with revenue received. A low BOPO will significantly affect the level of profit Islamic banks to improve the quality of ROA. Furthermore, more cost-effectiveness further increases the income so that the profit obtained is higher. Next, Bank Syariah Indonesia must use the number of funds in the banking sector to channel financing so that the risk of financing is getting higher reduced.
Design of Adaptive Sliding Mode Controllers for Perturbed Nonlinear Systems with Partial Unmeasurable States and State Constraints
Authors: Cheng Chih-Chiang , Lin Ting-Yu , Li Yu-Kuo
Published: November 2021

A sliding mode control (SMC) strategy is proposed in this paper for a class of perturbed nonlinear systems with unmeasurable states and state constraints to deal with the state tracking problems. First of all, a partial states observer is designed for solving the problems due to unmeasurable states. The estimation errors will approach zero in a finite time. Secondly, based on a designed barrier Lyapunov function, one designs the sliding surface function and an adaptive sliding mode tracking controller to ensure that the states have the ability to track the desired signals. Moreover, the tracking error is capable of converging to zero in a finite time without violating the given state's constraints. Perturbation estimator and adaptive mechanisms are also utilized so that there is no need to know the upper bounds of perturbations and perturbation estimation errors. Finally, a numerical example is provided to demonstrate the feasibility of the proposed control strategy.
Impact of Elevated Systolic Arterial Pulmonary Pressure on Short and Long Term All-Cause Mortality After Acute Myocardial Infarction in the Elderly
Authors: Barywani Salim , Johansson Magnus C , kontogeorgos Silvana , Mandalenakis Zacharias , Hansson Per-Olof
Published: November 2021

Background: Reduced left ventricular ejection fraction (LVEF) is associated with increased mortality after myocardial infarction (MI). However, the prognostic impact of elevated systolic pulmonary artery pressure (sPAP) in the elderly patients with MI is not well studied. Purpose: We aimed to study the impact of elevated sPAP on one- and five-year all-cause mortality after acute MI in patients 80 years of age and older.Methods: Of a total number of 353 patients(≥80 years old)that were hospitalized with acute coronary syndrome, 162 patients presenting with acute MI and with available data of sPAP on echocardiography were included and followed-up for 5 years. The survival analyses were performed using Cox-Regression models adjusted for conventional risk factors including LVEF.Results: Altogether 65 of 162 patients (40%) had ST-segment elevation MI, and 121 (75%) of patients were treated with percutaneous coronary intervention in the acute phase. Echocardiography during the admission revealed that 78 patients (48%) had a LVEF ≤ 45% and 65 patients (40%) had a sPAP ≥40 mmHg. After one and five years of follow-up, 23% (n=33) and 53% (n=86) of patients died, respectively. A multivariable Cox-Regression analysis showed that the elevated sPAP was an independent predictor of increased mortality in both one and five years after acute MI; HR of 3.4(95%, CI 1.4-8.2, P 0.006) and HR of 2.0(95%, CI 1.2-3.4, P 0.004) respectively, whereas LVEF did not show any statistically significant impact, neither on one- nor on five-year mortality (HR 1.4, 95% CI 0.8-2.4, p=0.158) and (HR 1.3, 95% CI 0.6-2.9, p=0.469), respectively.Conclusion:Elevated sPAP is an independent risk factor for one- and five-year all-cause mortality in patients with acute MI and it seems to be a better prognostic factor for death than LVEF. The risk of all-cause mortality in MI patients increased with increasing sPAP.
Comprehensive Evaluation of Caloric Restriction-Induced Changes In The Metabolome Profile of Mice
Authors: Xie Dadi , Huang Jinxi , Zhang Qiang , Zhao Shiyuan , Xue Hongjia , Yu Qing-Qing , Li Jing , Sun Zhuohao , Shao Minglei , Yang Xiumei , Pang Deshui , Jiang Pei
Published: November 2021

Objects: Caloric restriction (CR) is known to extend lifespan and exert a protective effect on organs, and is thus a low-cost and easily implemented approach to the health maintenance. However, there have been no studies that have systematically evaluated the metabolic changes that occur in the main tissues affected by CR. This study aimed to explore the target tissues metabolomic profile in CR mice.Methods: Male C57BL/6J mice were randomly allocated to the CR group (n = 7) and control group (n = 7). A non-targeted gas chromatography–mass spectrometry (GC–MS) approach and multivariate analysis were used to identify metabolites in the main tissues (serum, heart, liver, kidney, cortex, hippocampus, lung, muscle, and white adipose) in model of CR. Results: We identified 10 metabolites in the heart that showed differential abundance between the 2 groups, along with 9 in kidney, 7 in liver, 6 in lung, 6 in white adipose, 4 in hippocampus, 4 in serum, 3 in cortex, and 2 in muscle. The most significantly altered metabolites were amino acids (AAs) (glycine, aspartic acid, l-isoleucine, l-proline, l-aspartic acid, l-serine, l-hydroxyproline, l-alanine, l-valine, l-threonine, l-glutamic acid, and phenylalanine) and fatty acids (FAs) (palmitic acid, 1-monopalmitin, glycerol monostearate, docosahexaenoic acid, 16-octadecenoic acid, oleic acid, stearic acid, and hexanoic acid). These metabolites were associated with 8 different functional pathways related to the metabolism of AAs, lipids, and energy. Conclusion: Our results provide insight into the specific metabolic changes that are induced by CR and can serve as a reference for physiologic studies on how CR improves health and extends lifespan.
Asymmetric Determinants of CO2 Emissions in China: Do Government Size and Country Size Matter?
Authors: Lan Hai , Cheng Chengping , Sohail Muhammad Tayyab
Published: November 2021

CO2 emission reduction is a long-term strategy for China to promote its government and country size. However, this study examines the asymmetric impact of government size and country size on CO2 emissions in China. The study embraces the nonlinear ARDL framework of time series data analysis as proposed by Shin et al. (2014), which disentangles the positive and negative shocks to government size and country size. We find that the response of CO2 emissions to government size and country size positive shocks differs from the negative shocks. Empirical outcomes revealed that a positive shock of government size exerts an insignificant positive on CO2 emissions, while a negative shock of government size reduces CO2 emissions. More specifically, a positive shock of country size mitigates the CO2 emissions of China in long run. Policymakers should redesign the energy and environment policies in the framework of government size and country size.
Clinical Features of Congenital Pseudarthrosis of the Tibia in Children：a Study Focusing on 514 Cases in China
Authors: Zhou Yijun , Tan Qian , Liu Kun , Liu Yaoxi , Zhu Guanghui , Mei Haibo , Yang Ge
Published: November 2021

Background: Congenital pseudarthrosis of the tibia (CPT) is a refractory and rare disease. Because of its extremely low incidence, little is known about its clinical features. In this retrospective study, the aim of this study was to analyze the clinical characteristics of patients with CPT. Methods: This is a retrospective study of children with CPT identified by radiological review. Investigations of CPT included general condition, the characteristics of CPT, treatment methods and surgical complications. Results: We have collected 514 CPTs from 1999 to March 2020 in our hospital, 317 (61.67%) boys, 197 (38.33%) girls; 330 (62.86%) in Crawford IV; 510 (97.14%) in mid and distal 1/3 tibia; 481 (93.58%) in less than 3 years of first appearance of symptom; 297 (57.78%) in less than 3 years of the first visit of outpatient. The most common postoperative complication was ankle valgus (101, 39.60%), followed by limb length discrepancy（91, 35.69%), refracture (38, 14.90%), osteomyelitis (15, 5.88%) and removal of internal fixation (10,3.93%) . Conclusions: CPT with higher incidence of Crawford IV frequently occurs in boys and middle or distal part of the tibia; most patients have the first appearance of symptom and the first visit of outpatient before 3 years; the major surgical complications were ankle valgus and limb length discrepancy.
Effect of A Positive Cumulative Fluid Balance On The Prognosis of Patients With Sepsis In The Xining Area
Authors: Ma Si-Qing , Wang Yun , Sun Bin , Wang Hao , Xu Xue-Xia , Yin Zhi-ying , Luo Junming
Published: November 2021

Background: The aim of this work is to analyze the effect of a positive cumulative fluid balance and relative clinical indicators on the prognosis of patients with sepsis in the Xining area, China.Methods: The clinical data of 480 sepsis patients (313 males and 167 females, aged 52–77 (65) years) admitted between January 2017 and December 2019 were retrospectively analyzed. The APACHE II score, SOFA score, SIRS score and clinical laboratory test indicators of the patients were collected. Receiver operating characteristic (ROC) curves were used to analyze the sensitivity and specificity of each indicator in predicting the poor prognosis of patients with sepsis, and the maximum Youden index was used to determine threshold values. Cox regression analysis was performed to assess patient prognosis using data from patients with different fluid balances. Results: The following clinical indicators were significantly different between the 2 groups (P<0.05): APACHE II score, SOFA score, SIRS score, PCT, IL-6, BNP, CRP, PLT, BUN, CREA, Lac and total fluid balance from days 1 to 5. The area under the ROC curve (AUC) for total fluid balance from days 1 to 5 was 0.558, the cut-off value was 2120.5 mL, the sensitivity was 54.0%, and the specificity was 58.1%. The survival rates were different between the 2 groups (60.9% vs 48.9%, P<0.05). Total fluid balance was significantly higher in patients with septic shock and with Lac>2.0 mmol/L (P<0.05). Cox regression analysis indicated that APACHE II score, SOFA score, PLT score, Lac, and total fluid balance from days 1 to 5 were independent risk factors for poor prognosis.Conclusion: A positive fluid balance from days 1 to 5 after ICU admission was associated with poor patient outcomes and was an independent risk factor for poor patient prognosis.