bluuebunny/crossref_metadata_2025 huggingface dataset:
Alteraciones en células neuronales y cardiacas en la infección por el virus Zika
Authors: Ocaña Sánchez Marcos Fernando , Aguilar Guardado Kathia Liliana , Guzmán Martínez Oscar , Castro Gerónimo Van Dan , Hernández Baltazar Daniel
Published: December 2022

La principal complicación de la infección por virus Zika es la microcefalia desarrollada en bebés nacidos de madres infectadas. Desde hace unos años esto ha ido en aumento, por lo que resulta de gran relevancia estudiar los mecanismos moleculares involucrados. En este trabajo se realizó una revisión sistemática de artículos compilados en PUBMED para identificar los avances que se tienen en la actualidad respecto a esta patología, usando palabras clave como Zika virus, células neuronales, células cardiacas, estudios clínicos. Se encontró que las principales células atacadas en el sistema nervioso central son las células progenitoras neurales, la astroglía y la microglía, aunque de igual manera se tienen gran interés en el músculo cardiaco y el paso del virus hacia el sistema circulante, debido al gran tropismo presentado por este virus y su persistencia a lo largo de varios años, lo que complica el manejo correcto de la enfermedad. A pesar de tener un gran avance en el tema, aún falta elucidar totalmente los mecanismos que conllevan al desarrollo de la microcefalia, el impacto que tiene el virus en el tejido cardiaco, así como en otros tejidos, para poder comenzar a desarrollar tratamientos adecuados.
Trastornos de ansiedad: revisión bibliográfica de la perspectiva actual
Authors: Macías Carballo Monserrat , Pérez Estudillo Cesar , López Meraz Leonor , Beltrán Parrazal Luis , Morgado Valle Consuelo
Published: December 2022

Los trastornos de ansiedad son un problema creciente de salud pública que necesita la atención de personal especializado y capacitado. En la actualidad son 11 los trastornos de ansiedad (TA) clasificados en el DSM-V, todos con algunas características clínicas similares como angustia y miedo. La prevalencia general de estos trastornos oscila entre el 4-24% en diferentes países. En México no se tiene información actual debido a la falta de datos reportados por encuestas nacionales. Se han descrito una serie de tratamientos no farmacológicos y farmacológicos para el control de estos trastornos, sin embargo, aún se requiere de más investigación para encontrar nuevos tratamientos que no generen efectos secundarios. El objetivo de esta revisión es describir los criterios diagnósticos para los TA, la prevalencia y tratamientos.
Molecular and epigenetic mechanisms associated with extinction of fear memory: a systematic review
Authors: Esmaile Campanelli Stephany , Medeiros da Rocha Jaerdyson , Nobre Oliveira Jonas Ivan
Published: December 2022

Introducción: La presente revisión sistemática tiene como objetivo analizar los artículos entre 2011 y 2017 que describen la participación de los mecanismos epigenéticos y moleculares asociados con la extinción de la memoria del miedo. Método: Se consideraron los criterios de inclusión y exclusión para filtrar los artículos finales extraídos de Science Direct, Pubmed y Google Scholar. Resultados: De un total de 461 artículos, 13 cumplieron con los criterios y se mostraron en una tabla dividida en: Objetivo, Región del cerebro, técnicas y referencia. Estos últimos artículos fueron analizados críticamente y comparados entre si. Discusión: El análisis de la eficacia de los medicamentos y los mecanismos moleculares implicados en la extinción y / o la consolidación de la memoria del miedo en ratones y ratas pueden dilucidar y, por lo tanto, contribuir al tratamiento del trastorno obsesivo-compulsivo, la ansiedad, la fobia, el pánico y el estrés postraumático.
Patrones de movimiento en campo abierto de la rata con conducta autista sometida a estimulación musical
Authors: Monje Reyna Daniela , García Hernández Luis I , Coria Ávila Genaro A , Toledo María R , Hernández-Aguilar María E , Manzo Denes Jorge
Published: December 2022

El trastorno del espectro autista se manifiesta con una serie de alteraciones sensoriales y del comportamiento de distinta intensidad y severidad, por lo que su diagnóstico se basa en la evaluación conductual. La activación sensorial auditiva, mediante la estimulación musical, es una de las intervenciones que se han implementado para revertir este trastorno. Sin embargo, en modelos animales aún no se ha evaluado el impacto de la estimulación musical. Este trabajo implementó la estimulación musical en un modelo de inducción posnatal de autismo, donde se expuso a ratas Wistar a música clásica desde el día p1 al p30 para evaluar conductas motrices en campo abierto. Sujetos de ambos sexos presentaron mayor actividad locomotriz cuando recibieron la estimulación musical en comparación con el grupo que no estuvo expuesto. Estos datos sugieren que la vía auditiva activa significativamente a los circuitos involucrados en la locomoción.
Patrones conductuales de monos vervet en cautiverio sin contacto con visitantes
Authors: Ortiz Rueda Gerardo Alfonso , López-López María José
Published: December 2022

Los animales poseen la capacidad de ajustar su comportamiento en correspondencia con los estímulos y relaciones entre estímulos, cambiantes momento a momento, que conforman su entorno; así, podría esperarse que un organismo expuesto a diferentes entornos (i.e. distinto número, tipo y distribución geográfica de objetos, presencia/ausencia de otros individuos) exprese patrones de comportamiento individuales distintos, independientes de su pertenencia a una especie, que le permitieran ajustarse a los cambios del medio. Con el fin de estudiar este ajuste conductual a diferentes condiciones, usando un método focal con registro continuo, se realizó una observación sistemática de la conducta desplegada por un grupo de monos vervet (Cercopithecus aethiops pygerythrus), pertenecientes al Zoológico Guadalajara (México), detectando la temporalidad y espacialidad de los patrones conductuales. Se videograbó a los sujetos, en un periodo de 30 días consecutivos, durante 160 minutos al día, 20 minutos por cada individuo, en dos secuencias (i.e. 40 min por individuo por día). En general, al igual que en estudios previos, pero con valores inferiores, los resultados indican que las conductas de descanso predominaron en los cuatro sujetos, mientras que a la locomoción se dedicó cerca de una décima parte del tiempo. A partir de la comparación de los resultados de distintos estudios con el grupo observado en el presente trabajo, se discute en términos de la posible relevancia funcional que tienen factores de tipo geoecológico y de interacción, así como condiciones de manejo, en la emisión y distribución espacio-temporal del comportamiento de animales en cautiverio.
Perbandingan Pertumbuhan Pagoda antara Larutan Nutrisi AB Mix dan Pupuk Organik Cair pada Sistem Hidroponik NFT
Authors: Yulianti Fitri
Published: December 2022

Pagoda is a leaf vegetable plant that has a unique shape when compared to other types of mustard greens because the shape of this pagoda mustard is similar to a blooming flower, oval leaf shape with a very striking dark green colour, short-lived and has many nutrients and benefits. Vegetable cultivation technique using a hydroponic system that is often used is NFT (Nutrient Film Technology) because the design is quite simple to use. An important factor that must be considered in a hydroponic system to obtain optimal plant growth results is the need for nutrients. AB mix nutrition is a chemical fertilizer which is one of the standard nutrients used in hydroponic systems. The use of Liquid Organic Fertilizer (LOF) is expected to be an alternative hydroponic nutrient solution so that the vegetables produced are healthier, or what we are familiar with organic vegetables. The aim of the study was to compare the growth of pagoda plants against two types of nutrient solutions (AB mix and LOF) in the NFT hydroponic system. The research was carried out from March to April 2019 at Greenhouse, East Jakarta. The experimental design used was a completely randomized design. The treatment was the type of nutrient solution (AB mix and LOF) and was repeated 3 times. Observational data were analysed using t-test at 5% significance level. The results showed that pagoda growth in AB mix treatment was better than LOF so that LOF had not been able to become an alternative to AB mix for hydroponic nutrient solution for pagoda plants.
Pengaruh Pupuk Rock Phosphate dan Pupuk Dolomit Terhadap Produksi Kelapa Sawit (Elaeis guineensis Jacq.) di Divisi I PT. Dwi Mitra Adiusaha
Authors: Sugiyarto Sugiyarto , Harlianingtyas Irma , Triwidiarto Cherry , Supriyadi Supriyadi
Published: December 2022

Oil palm in the process of development is grown in low or marginal nutrients and has a moderate acidity level. In the development process, oil palm requires high enough nutrients for the process of spurring the production process in order to get the expected results, therefore fertilization is carried out optimally with doses according to the recommendations that have been set so that the plants can meet the required nutrients. To increase the yield of fertilization, using rock phosphate and dolomite is very appropriate to get the nutrients needed and can improve the quality of oil palm fruit and the quantity of fresh fruit bunches of oil palm. The effect of Rock Phosphate and Dolomite fertilizers on the production of oil palm (Elaeis Guineensis Jacq) was carried out in the oil palm plantation of PT. Dwi Mitra Adhiusaha which is located in Natai Baru Village, North Mentaya Hilir District, East Kotawaringin Regency, Central Kalimantan. This activity was carried out by analyzing secondary data for both Rock Phosphate fertilizers from 2016 to 2020 and secondary production data from 2017 to 2021. This data analysis used the SPSS method and multiple linear regression which showed that fertilization had a positive correlation and regression towards achievement of oil palm fresh fruit bunches production at PT. Dwi Mitra Adiusaha.
Respon Pertumbuhan dan Produksi Tanaman Jagung Manis (Zea mays saccharate Sturt.) Terhadap Pemberian Berbagai Pupuk Organik Cair
Authors: Cahyani Intan Dwi , Eliyatiningsih Eliyatiningsih
Published: December 2022

Sweet corn is still a leading horticultural commodity that is much favored by the people of Indonesia because it has a sweeter taste than ordinary corn. Cultivation of sweet corn so far is often constrained in the aspect of fertilization. Fulfillment of nutrients so far is mostly done through inorganic fertilization, which if not balanced with the use of organic fertilizers can have a negative impact on the cultivation environment. This study aims to determine the response of growth and production of sweet corn plants to the application of various liquid organic fertilizers. This study used a non-factorial randomized block design (RAK) model consisting of 4 levels of treatment, namely P0 (control), P1 (rabbit urine), P2 (cow urine), and P3 (goat urine) with 6 replications. The results of the F test showed that the treatment of various types of liquid organic fertilizers had a significant effect on the parameters of the cob diameter and weight of the sweet corn cobs, and gave a very significant effect on the parameters of the sweet corn's sweetness level. The results of the DMRT test showed that the application of liquid organic fertilizer of cow urine (P3) with a concentration of 200 ml/l gave the best results for the parameters of cob diameter, cob weight, and sweet corn level.
Pengaruh Alelopati Tanaman Gamal (Glericida manuculata) Dan Kirinyuh (Eupatorium odoratum) Terhadap Perkecambahan Kacang Hijau (Vigna radiata)
Authors: Nugroho Setyo Andi , Setyoko Ujang , Fatimah Titien , Novenda Ika Lia
Published: December 2022

Gamal (Glericida manuculata) is used by farmers as a coffee shade plant and as animal feed, kirinyuh (Eupatorium odoratum) grows as a weed. Both plants have allelopathic substances that inhibit the growth of cultivated plants. Gamal plants produce allelopathic substances from the saponin and polyphenol groups. Kirinyuh plant produces allelopathic substances such as flavonoids, alkaloids, tannins, and limonene. The aim of the research was to determine the effect of allelopathy of gamal and kirinyuh plant species on mung bean germination. The method used extracts of gamal and kirinyuh plants with concentrations of 46%, 36%, and 26%. The results showed the effect of allelopathic plant species on the growth of mung bean epicotyl, extract treatment of gamal plant on the 10th day of longest epicotyl length was 36% concentration, which was 29.7 mm, the shortest was 46% concentration of 6.7 mm. Kirinyuh plant extract on day 10 of the shortest epicotyl growth with 46% extract was 16 mm, while the longest epicotyl growth was 36% at 21mm. Radicle length on day 10 for the shortest gamal plant extract was treated with a concentration of 46% at 17 mm, while the shortest kirinyuh plant extract was a concentration of 26% at 24 mm. The effect of allelopathic plant species on the percentage of mung bean germination for the 100% gamal extract treatment, namely the extract with a concentration of 36% and 26%, while the 46% extract had 93.33% germination. Kirinyuh plant extract had the highest germination percentage at 36% concentration treatment.
Pengaruh Penempatan Baglog dan Pemberian Komposisi Media Pada Produksi Jamur Tiram Putih (Pleurotus ostreatus)
Authors: Kusparwanti Tri Rini , Siswadi Edi , Sukri M. Zayin , Firgiyanto Refa , Kusumaningtyas Rizky Nirmala
Published: December 2022

White-Oyster mushroom (Pleurotus ostreatus) is one type of fungus that grows on wood. This mushroom full of many nutrients and can be used to substitute other nutritional sources that are relatively more expensive. One of important factor in the cultivation of white-Oyster mushroom, is the availability of the substrate as a growing medium. The medium of White-Oyster mushroom must contain with the nutrients needed for growth and production. The potential utilization of agricultural waste can be used as an alternative growing medium. One of them is peanut stover. The purpose of this study was to determine the best composition in the substitution medium of peanut stover and the efficiency room with a rack placement. This study is a factorial randomized block design (RAK) with 2 treatment factors. First is rack placement namely conventional racks (R1) and hanging shelves (R2) and composition of the media consisting of 100% sawdust (K1), 25% peanut stover + sawdust 75% (K2), peanuts stover 50% + sawdust 50% (K3), peanuts stover 75% +sawdust 25% (K4) with four replicates. The result of the study showed that the best media composition was in the treatment of (K2) 75% sawdust + 25% peanut stover.  In addition, for space efficiency on the number of baglogs, the results are significantly different with the value of R1 (conventional shelf alignment) greater than R2, which is 10525 grams.
Potensi Asap Cair Arang Sekam terhadap Spodoptera litura dan Pengaruhnya terhadap Keanekaragaman Artropoda pada Tanaman Kedelai Edamame
Authors: Syarief Mochamad , Erdiansyah Iqbal
Published: December 2022

This study aimed to examine the potential of husk charcoal liquid smoke as a bioinsecticide in controlling S. litura and its effect on the diversity of arthropods in Edamame soybeans. The research was conducted from February 2021 to June 2021, at The Plant Protection Laboratory, Bioscience Laboratory Jember State Polytechnic and farmers' land in Balung Lor Village, Jember Regency. Laboratory research examines the bioactive components of 3rd grade husk charcoal liquid smoke, toxicity. The treatment of liquid smoke of husk charcoal, compared with Fipronil as a positive control, used the Mann Whitney test. Observations were: S. litura population, damage intensity, pod weight per plant and arthropod diversity. The results of the the research were: GCMS analysis showed that the liquid smoke of husk charcoal 3rd  grade  contains 35 components that were detected by a mass spectrometer. The bioactive compound as an antifeedant with the highest concentration was Acetic Acid, ws 37.03%. LC50 and LC95 were 9% and 28% respectively; The liquid smoke of husk charcoal was more effective in reducing the population of  S. litura and the damage intensity; pods weight 48.92 grams per plant, Fipronil 23.92 grams per plant. Shannon Wiener Diversity Index of husk charcoal liquid smoke was 2.57 Fipronil was 1.85, Sorensen similarity index was 77% (different). The dominance index of Simpson bioinsecticide liquid smoke husk charcoal was 0.10 lower than Fipronil, which was 0.54.
Uji Beberapa Jamur Antagonis Terhadap Colletotrichum gloeosporiodes Penyebab Penyakit Busuk Buah Apel Manalagi (Malus sylvestris) Secara In Vitro
Authors: Triasih Unun , Abadi Abdul Latief , Muhibbudin Anton , Widyaningsih Sri
Published: December 2022

Colletotrichum Gloeosporiodes is one of the pathogenic fungi that causes fruit rot disease in apple plants. The control that has been widely used so far is chemical fungicides which cause negative effects, it is necessary to use an alternative control using antagonistic fungi that is safe and environmentally friendly. This study aims to determine the inhibition of several antagonistic fungi against the growth of the pathogen C. gloeosporiodes. The method used was a completely randomized design (CRD) with 4 types of antagonist fungi, 1 control and 5 replications. Antagonism test using dual culture method between antagonistic fungi Trichoderma harzianum, Trichoderma viridae, Trichoderma koningii, and Gliocladium sp. with C. gloeosporiodes. The test results showed that the antagonist fungus that had the highest percentage of inhibition against C. gloeosporiodes was T. harzianum at 87.8% and had a high inhibitory power category with a crude extract chitinase enzyme activity value of 4.30 U/mL and Gliocladium sp. has the lowest percentage of inhibition 64.3%. Based on these results, it can be concluded that T. harzianum has a high potential to control fruit rot disease in apples because it contains the chitinase enzyme which can degrade the cell wall of the pathogenic C. gloeosporiodes.
Satisfação acadêmica no contexto da pandemia da Covid-19 em estudantes do Ensino Superior
Authors: Pereira Neto Lauro Lopes , Faria Ana Amália Gomes de Barros Torres , Almeida Leandro Silva
Published: December 2022

Este artigo apresenta os resultados da investigação sobre os fatores psicossociais que impactaram a satisfação acadêmica dos estudantes do Ensino Superior relacionados ao seu desempenho acadêmico durante o Ensino Remoto Emergencial. Por meio da aplicação do Questionário de Satisfação com a Experiência Acadêmica Remota, objetivou-se avaliar o nível de satisfação acadêmica de uma amostra de 365 estudantes matriculados nos cursos superiores do Instituto Federal de Alagoas. A satisfação acadêmica foi diretamente impactada pela vulnerabilidade social e digital dos estudantes, especialmente entre os de maior idade quanto à satisfação com os recursos econômicos, à perspectiva de realização profissional futura e à empregabilidade. Mesmo não possuindo uma infraestrutura digital satisfatória para o acompanhamento das atividades remotas, a maior parte dos estudantes mostraram-se motivados para a continuidade dos estudos, pois acreditavam que só com o investimento na própria formação acadêmica iriam garantir a mobilidade social ascendente tão almejada.
Effects of Led Light Intensity and Carbon Dioxide Concentration on the Growth of Spinach (Spinacia oleracea L.) in a Plant Factory
Authors: Thuy Pham Chau , Khanh Nguyen Le , Duy Nguyen Nhu
Published: December 2022

This research aimed to investigate the effects of light intensity and the carbon dioxide (CO2) concentration on spinach’s growth during vegetative stage in plant factory (PF). Two experiments were conducted with different CO2 concentration in closed chamber (500 ppm and 800 ppm). In each experiment, plants were hydroponically grown under three light intensities of 115, 140 and 160 µmol.m-2s-1. Growth’s parameters were determined at different growth stages (T30, T37 and T44 respectively to 30, 37 and 44 days after sowing). ANOVA analysis and non-parametric Kruskal analysis of variance were used to evaluate the statistical significance of the treatment effects. The results showed that, before 30 days old, the increase of light intensity was not significantly effected to the growth of plant. During later growing periods (30 days old afterward), the increase of light intensity remarkably boost up yield’s related traits such as leaf number, fresh mass and dry mass under 500ppm CO2 concentration. The combination of light intensity and CO2concentration at 800ppm showed the plant growth indicators increased significantly at the T37 and T44 stages (after 30 days old), especially at the last week of growth period, fresh weight and dry weight of plants were significantly different at the light treatment L2, increased 37% and 57.6%, respectively as compared to light treament only. The results suggested that, during latest growing period, the average light intensity of 140 µmol.m-2s-1combining with elevating CO2 concentration is an alternatively way to enhance spinach growth. The findings of this study could be helpful for growers to improve growing conditions for a better development of spinach in the indoor farming (PF)
Ridesharing Options from Geosynchronous Transfer Orbits to the Sun–Earth L1 Region
Authors: Ojeda Romero Juan A. , Howell Kathleen C.
Published: December 2022

Ridesharing options for secondary payloads to be delivered to regions beyond geostationary altitude are increasingly available with propulsive evolved expendable launch vehicle secondary payload adapter rings. The preliminary mission design for secondary payloads must consider the variability of the dropoff orbit orientation: a factor that is a function of the primary mission. In this analysis, assume that the dropoff orbit is an Earth-centered geosynchronous transfer orbit (GTO). Then, propellant-efficient transfers to periodic and quasi-periodic orbits near the Sun–Earth [Formula: see text] Lagrange point are constructed from a range of GTO orientations. Dynamical structures (such as hyperbolic invariant manifolds) associated with orbits near Sun–Earth [Formula: see text] Lagrange point are leveraged to identify and summarize various types of transfer opportunities.
La formación del clero argentino en el Colegio Pío Latino Americano. Los alumnos de la diócesis de Córdoba (Argentina) y la consolidación de un modelo eclesial romano (1877-1927)
Authors: Gallardo Milagros
Published: December 2022

El Colegio Pio Latino Americano, fundado en Roma en 1858, supuso un hito en el proceso de romanización del clero argentino. El trabajo busca analizar el impacto de este «grupo romano» en la construcción de una matriz de formación del clero, dado que un significativo número de exalumnos ocuparon funciones de docencia en el seminario local. Para ello, identificamos a los alumnos enviados a Roma por la diócesis de Córdoba entre 1877 y 1927, analizamos la composición del grupo, la formación que recibieron en sus años de instrucción y reconstruimos las trayectorias personales a su regreso. La hipótesis que planteamos es que la formación del clero en el Colegio Pio Latino no fue impulsada, en el caso cordobés, por los obispos diocesanos. El envío de alumnos fue, fundamentalmente, un interés de las familias acomodadas de Córdoba, que enviaron a estudiar a sus hijos a Roma y los sostuvieron económicamente. A su regreso, ocuparon cargos de gobierno y administración eclesiástica. La promoción y difusión del colegio en la diócesis respondió, casi exclusivamente, a la iniciativa de los exalumnos, al menos hasta 1927, en que es nombrado como obispo diocesano Monseñor Emilio Laffite, un exalumno del Pio Latino. Del grupo analizado, cinco alcanzaron la mitra episcopal y fueron destinados a otras diócesis argentinas y tres de ellos fueron arzobispos. ¿Es posible plantear la construcción de una matriz romana para el gobierno de las diócesis o Iglesia particulares? Esto, sin duda, es tema de otro trabajo.
Intelectuales «satélites»
Authors: Carranza Mariño Yadira
Published: December 2022

Fernando Aínsa y Roger Caillois fueron dos intelectuales que actuaron como bisagras culturales entre el continente europeo y latinoamericano. Habiendo vivido en las dos orillas del Atlántico, los escritores fueron construyendo, a través de sus desplazamientos, redes trasatlánticas que funcionaron como mecanismos de circulación de transferencias culturales. Sus acciones por la difusión y promoción de autores provenientes de América Latina los llevaron a convertirse en mediadores. Actores en «segunda fila» cuya contribución en la historia de la producción cultural merece ser rescatada y puesta en perspectivas para recuperar los eslabones perdidos de la historia trasatlántica. Desde París, «capital de las letras», Aínsa y Caillois instauraron una pasarela de textos latinoamericanos a territorio europeo, sus contactos en el mundo editorial, la academia, las revistas y las organizaciones internacionales como la Unesco les permitió crear conexiones con revistas como Río de la Plata, América, El correo de la Unesco y vincularse a proyectos editoriales como la Colección Croix du sud, Obras representativas y Archivos, desde donde actuaron como «passeurs» de la literatura latinoamericana.
Hernando Téllez y Eduardo Caballero
Authors: Guapacha Romero Marisela
Published: December 2022

El presente artículo propone una comprensión del concepto del compromiso social del escritor a partir de los planteamientos de Jean-Paul Sartre (1950) y autores hispanoamericanos como Juan Goytisolo, Juan Fernando Taborda, Rubén Sierra y Carlos Osorio, que problematizan este concepto y reflexionan sobre las dinámicas y condiciones a las que está supeditado quien escribe. Dichas concepciones sobre el compromiso social del escritor entran en diálogo con las figuras de Hernando Téllez y Eduardo Caballero, las ideas intelectuales de los mismos, su labor diplomática y periodística, las situaciones que debieron afrontar al tomar la decisión de escribir sobre la problemática del país y sus contribuciones al campo literario colombiano. Por último, se hace un análisis de algunos cuentos seleccionados de Téllez y de la novela Manuel Pacho de Caballero, a la luz de la categoría propuesta. Esta última se dividirá en tres subcategorías que guiarán el análisis y a su vez permitirán evidenciar el compromiso de estos escritores con el conflicto armado bipartidista al igual que sus diferentes aportes a la historia y a la transformación social de la nación.
Efficiency Investigation of BT-Object Based Partial Evaluation of Interpreters Written in the Java Object-Oriented Language
Authors: Адамович Игорь Алексеевич , Климов Юрий Андреевич
Published: December 2022

Барьеры на пути специализации реальных программ, написанных
в объектно/̄ориентированной парадигме, часто могут быть преодолены при
помощи современных методов метавычислений. Один из барьеров —
необходимость разрешения полиморфизма на этапе анализа программы, до ее
исполнения. Эта проблема успешно решается для ряда случаев
в специализаторе JaSpe, что показано в данной статье. Работа посвящена
компиляции программ с использованием метода специализации, без
использования компилятора. Мы применили специализатор JaSpe, основанный
на методе частичных вычислений, к двум интерпретаторам языка
арифметических выражений, написанным на Java. Интерпретаторы были
реализованы методом рекурсивного спуска и с использованием шаблона
«посетитель». В результате успешной специализации данных интерпретаторов
по  программе вычисления квадратного корня на языке арифметических
выражений были получены скомпилированные версии программы на языке Java.
При этом скорость полученных версий программы по сравнению с исходной
увеличилась в 12-22 раза.
Import Substitution Experience in the Interin PROMIS Alpha Healthcare Information System
Authors: Белышев Дмитрий Владимирович
Published: December 2022

Импортозамещение в части систем управления базами данных является
насущной задачей, стоящей перед многими производителями информационных
систем. В нашей работе мы рассматриваем опыт миграции медицинской
информационной системы Интерин PROMIS из технологий Windows/Oracle
в технологии на основе Linux/PostgreSQL, рекомендуемые Реестром
отечественного ПО. Дается оценка двух подходов к миграции модулей
информационной системы: на основе перепроектирования с использованием
инструментов платформы Интерин Alpha PG и на основе автоматической
конвертации собственными инструментальными средствами.
The Effect of Intrinsic Motivation and Religiousity to Social Media Awareness Around 'Fodamara Tv' Youtube Team
Authors: Lubis Nurfauzy , Handayani Nureta Dwika , Aisyah Insanul
Published: December 2022

Salah satu kelompok remaja masjid yang bergerak menjadi dai virtual adalah Forum Remaja Masjid Raya (Fodamara) Senapelan, Pekanbaru. Mereka memulai aktivisme dakwahnya di media sosial melalui kanal Youtube “Fodamara TV”. Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh antara motivasi intrinsik dan religiusitas terhadap kesadaran dakwah media sosial di kalangan tim youtube ‘Fodamara TV’. Penelitian ini merupakan deskriptif kuantitatif dengan teknik sampling sensus di mana seluruh populasi dijadikan sampel yang berjumlah 35 orang. Hasil penelitian dari uji regresi berganda menunjukkan bahwa variabel motivasi intrinsik dan religiusitas sama-sama berpengaruh terhadap variabel kesadaran dakwah dengan sebesar 85,4%. Selain itu, besarnya pengaruh antara motivasi intrinsik dan religiusitas (secara simultan) terhadap kesadaran berdakwah signifikan sebesar 0,636. Begitu juga untuk variabel religiusitas memberikan pengaruh yang signifikan sebesar 0,467.
Построение обобщенных итерационных методов, используемых для решения интегрального уравнения Фредгольма
Authors: Mande X. , Boukansous S. , Tair B. , Guebbai H.
Published: December 2022

In this paper, we consider the Fredholm integral equations of the second kind and construct a new iterative scheme associated to the Nyström method, which was elaborated by Atkinson to approximate the solution over a large interval. Primarily, we demonstrate the inability to generalize the Atkinson iterative methods. Then, we describe our modified generalization in detail and discuss its advantages such as convergence of the iterative solution to the exact solution in the sense norm of the Banach space С0[a,b]. Finally, we give a numerical examples to illustrate the accuracy and reliability of our generalization.

В данной работе мы рассматриваем интегральные уравнения Фредгольма второго рода и строим новую итерационную схему, связанную с методом Нистрема, который был разработан Аткинсоном для аппроксимации решения на большом интервале. Прежде всего, мы демонстрируем невозможность обобщения итерационных методов Аткинсона. Затем мы в деталях описываем наше модифицированное обобщение и обсуждаем его преимущества, такие как сходимость итерационного решения к точному в смысле нормы банахова пространства С0[a,b]. Наконец, мы приводим численные примеры, иллюстрирующие точность и надёжность нашего обобщения.
Soot and charcoal as reservoirs of extracellular DNA
Authors: Jelavic Stanislav , Thygesen Lisbeth Garbrecht , Magnin Valerie , Findling Nathaniel , Müller Sascha , Meklesh Viktoriia , Sand Karina Krarup
Published: December 2022

The vast potential of using sediment adsorbed DNA as a window to past and present biodiversity rely on the ability of solid surfaces to adsorb environmental DNA. However, a comprehensive insight into DNA adsorption at surfaces in general is lacking. Soot and charcoal are carbonaceous materials widespread in the environment where they readily can come in contact with extracellular DNA shed from organisms. Using batch adsorption, we measured DNA adsorption capacity at soot and charcoal as a function of solution composition, time and DNA length. We observed that the adsorption capacity for DNA is highest at low pH, that it increases with solution concentration and cation valency and that the activation energy for DNA adsorption at both soot and charcoal is ~50 kJmol-1, suggesting strong binding. We demonstrate how the interaction between DNA and soot and charcoal partly occurs via terminal base pairs, suggesting that, besides electrostatic forces, hydrophobic interactions play an important role in binding. The large adsorption capacities and strong binding of DNA to soot and charcoal are features important for eDNA research and provide a motivation for use of carbonaceous materials from, e.g., anthropogenic pollution or wildfire as sources of biodiversity information.
Uncertainty-calibrated deep learning for rapid identification of reaction mechanisms
Authors: Liu Yan , Mo Yiming , Cheng Youwei
Published: December 2022

Analyzing the reaction mechanism is the cornerstone across all chemistry disciplines. However, the existing reaction mechanism data only have limited coverage of the enormous chemical space and are usually collected from various sources, thus, limiting advanced machine learning tools to facilitate classical computational chemistry approaches for obtaining reaction mechanisms. Herein we present an uncertainty-calibrated learning-to-ranking (UC-LTR) model for constructing mechanistic reaction networks. UC-LTR model can make efficient and accurate prediction with quantitative uncertainty learned from inconsistent and sparse data sources. This allows a coherent utilization of existing data, improving the confidence of using predicted results for the following experimental or quantum chemistry refinement. We demonstrated this approach can provide efficient and reliable identification of reaction networks for high-temperature gas-phase reactions. This work showcase a practical deep learning strategy in fields of chemistry where the availability of high-quality big data is limited
Interpretable machine learning on metabolomics data reveals biomarkers for Parkinson’s disease
Authors: Zhang J. Diana , Xue Chonghua , Kolachalama Vijaya B. , Donald William A.
Published: December 2022

The use of machine learning (ML) with metabolomics provides opportunities for the early diagnosis of disease. However, the accuracy and extent of information obtained from ML and metabolomics can be limited owing to challenges associated with interpreting disease prediction models and analysing many chemical features with abundances that are correlated and ‘noisy’. Here, we report an interpretable neural network (NN) framework to accurately predict disease and identify significant biomarkers using whole metabolomics datasets without feature selection. The performance of the NN approach for predicting Parkinson’s disease (PD) from blood plasma metabolomics data was significantly higher than classical ML methods with a mean area under the curve of > 0.995. PD-specific markers that contribute significantly to early disease prediction were identified including an exogenous polyfluoroalkyl substance. It is anticipated that this accurate and interpretable NN-based approach can improve diagnostic performance for many other diseases using metabolomics and other untargeted ‘omics methods.
The Samarsky – Ionkin Problem with Integral Perturbation for a Pseudoparabolic Equation
Authors:   Sobolev Institute of Mathematics SB RAS, Kozhanov A I. ,   Academy of Sciences of the Republic of Sakha (Yakutia), Tarasova G. I. ,   North-Eastern Federal University
Published: December 2022

In the work the solvability of nonlocal boundary value problems for thirdorder pseudoparabolic equations in anisotropic spaces of Sobolev is studied. The condition is specified by a spatial variable that combines the generalized Samarsky-Ionkin condition and the integral type condition is particularity of the problems under study. The work aim is to prove the existence and uniqueness of the problems regular solutions - the solutions that have all Sobolev derivatives included in the corresponding equation.
Tikrar al-Muhyi: Development of a Pocketbook for Memorizers of the Qur'an
Authors: Puspitasari Niken Sylvia , Akbar Ahmad Fadly Rahman , Cahyani Alivia Bunga
Published: December 2022

Memorizing the Quran preserves its authenticity. During al-Qur'an memorization, a hafizh may face obstacles that make it difficult to memorize the verses. Forgetting memorized verses when adding new ones, many similar verses, lack of focus due to environmental factors, changing al-Qur'an manuscripts, and rarely reading verses to be memorized are obstacles in murojaah. This research aims to develop learning media in the form of pocketbook Tikrar al-Muhyi as an easy solution to murajaah al-Qur'an. This research uses the R&D method, which adopts the development of Borg & Gall. Subjects in this study were students of the University of Darussalam Gontor. Data Collection using questionnaires given to subject material experts, media experts, and students to test the feasibility of the media learning pocketbook. The research findings show that the development of this book is very feasible, with a percentage of 80% based on media and material experts. Furthermore, the eligibility increase was 94% after the second stage test. This research has contributed to Islamic education, especially about media that makes it easier to memorize the al-Qur'an.
Syed Muhammad Naquib al-Attas' Concept of Islamizing Science and its Relevance to Islamic Education
Authors: Puspitasari Eka , Yuliana Anaas Tri Ridlo Dina
Published: December 2022

Islamic education has become less moral due to the religious and general science separation. This split in science is blamed on the West's secularization. Adding religious and general science to the Islamic education curriculum can solve this problem. This study aims to determine what Syed Muhammad Naquib Al Attas meant by Islamizing science and how it relates to Islamic education. This article uses qualitative descriptive research that blends history and philosophy. This study used Syed Muhammad Naquib Al Attas's books, other documents, books, and articles. According to Syed Muhammad Naquib al-Attas, the idea of Islamizing science is to free people from magical, mythological, animistic, cultural-national traditions that go against Islam, as well as from the chains of a secular understanding of thought and language and the control of their physical impulses that are often secular and unfair to their nature or soul. Islamic education develops the body, spirit, and mind (Insan Kamil). This research contributes to Islamic education by strengthening the epistemology of the Islamization of science and its relation to Islamic education.
Leadership of School Principals to Improving Teacher Professionalism at Muhammadiyah School
Authors: Yusutria Yusutria , Hopid Abdul , Febriana Rina
Published: December 2022

The principal's leadership increases teachers' work motivation and improves education quality. The study examined the principal's leadership in improving teacher professionalism at SD Nitikan Muhammadiyah Yogyakarta. This qualitative descriptive research uses interviews, observation, and documentation. This study involved the principal and 25 teachers as informants. The principal's strategy to improve the quality and professionalism of teachers is to motivate, encourage, and organize training on IT development, reward, and punishment. Principals must also meet content, process, graduation capacity, facilities and infrastructure, management, funding, teacher and staff, and teacher education standards. Supporting factors provide teachers with equal opportunities to develop their pedagogical and professional skills through teaching and training activities based on knowledge and adapted to needs and budgets. Lack of internal motivation from teaching priorities is a barrier. This research contributes to the development of Islamic education by analyzing principals' efforts to increase teachers' professional capacity in Islamic schools.
Effect of pretreatment on nutrient content and antioxidant properties of
Mangifera odorata L. peel and seed kernel powder
Authors: M. Tun Norbrillinda , H. Hasri , M. Syahida , I. Norra , H. Hadijah
Published: December 2022

This study was carried out to investigate the influence of pretreatment, such as steaming
and blanching, on the nutrient content and antioxidant properties of Mangifera odorata L.
fruit peel and seed kernel powder. Results showed that steaming and blanching could
increase the peel’s powder calories, carbohydrate and vitamin A content. A similar trend
was also observed on the dietary fibre content of the seed kernel powder. Conversely, the
vitamin C and dietary fibre content of the peel powder were degraded after undergoing
pretreatment. The protein content of the seed kernel powder had shown a decrement when
blanching, indicating that the steamed samples had better retention of the protein content.
It was observed that vitamin A and C were only detected in the peel powder, but fatty
acids were only found in the seed kernel powder. Blanching had decreased 24% of stearic
acid and 38% of methyl linolenate. Results of total dietary fibre showed that the values
were 22-77% higher in the peel than the seed kernel powder. Meanwhile, the seed kernel
showed higher antioxidant activity than the peel, although both samples showed EC50
values ≤ 1 mg/mL. These results might be useful to produce a powdered functional
ingredient from M. odorata fruit wastes.
Enhancing the Problem-Solving Skills of Vocational Students Through Skills Competition
Authors: Wang Shang , Peng Fei , Li Mengjie
Published: December 2022

Unlike general education, vocational education aims to nurture skilled people for various sectors in the society. The development of students’ problem analysis and problem-solving skills is crucial. As an important part of the vocational education system, skills competitions are considered a “booster” for improving the quality of teaching in vocational institutions. This paper examines the problem-solving skills of students in preparation for skills competition. First of all, we introduce China’s education policies and conduct a review of early scholars’ views, followed by a discussion on the specific problems faced in the design of the entry for skills competition and an exploration of the process of enhancing students’ problem-solving skills around these problems; we then propose several suggestions for vocational institutions to enhance their participation in skills competitions. Skills competitions provide a “special stage” for students in vocational institutions to show their abilities. The question of how this “stage” can be utilized to better improve students’ abilities is worth exploring in different fields.
DIAGNÓSTICO AMBIENTAL DA SUB-BACIA URBANA DO CÓRREGO DAS GARÇAS, EM JUÍNA, MATO GROSSO: MÉTODO VERAH
Authors: Souza Otoniel Nacimento de , Ribeiro Joaquim Corrêa
Published: December 2022

A presente pesquisa teve por objetivo realizar o diagnóstico ambiental da sub-bacia urbana do córrego das Garças, no município de Juína, localizado no Bioma Amazônia, norte de Mato Grosso, utilizando-se o método VERAH (Vegetação, Erosão, Resíduos, Água/Assoreamento e Habitação). A pesquisa compreendeu três etapas: 1) Levantamento de materiais bibliográficos e cartográficos existentes em diversos níveis de informações; 2) Delimitação da área da sub-bacia com uso de imagens e produtos cartográficos como mapa de uso e ocupação do solo e de declividade e 3) Realização do diagnóstico ambiental a partir dos temas propostos pelo método VERAH. Os resultados demonstraram comprometimento das Áreas de Preservação Permanente, com destaque para a margem esquerda da cabeceira de drenagem do Córrego das Garças, apresentando processos erosivos, destinação irregular de resíduos sólidos; possível comprometimento da qualidade da água, sedimentos em suspensão; ocupação irregular de áreas de APPs, além da ausência de rede de esgotos. Foi apresentado um quadro síntese com os principais problemas diagnosticados, além de propostas e recomendações.
İkiz Açık Hipotezi Türkiye’de Geçerliliği: Zamanla Değişen Nedensellik Analizi
Authors: ERER Elif
Published: December 2022

Finansal ve ekonomik istikrarın sürdürülebilirliği açısından iç ve dış dengenin birlikte sağlandığı maliye politikalarının uygulanması son derece önem arz etmektedir. Bu nedenle, cari işlemler ile bütçe açıkları arasındaki ilişkinin incelenmesi politika yapıcılar, araştırmacılar ve ekonomistler arasında tartışılan önemli konulardan biri haline gelmiştir. Bu kapsamda, çalışmada Türkiye için Ocak 1998 – Aralık 2021 döneminde ikiz açık hipotezi, Granger nedenselliğin geçici istikrarını yeniden değerlendirmek amacıyla kullanılan yinelemeli algoritmalar kullanılarak araştırılmaktadır. Zamanla değişen Granger nedensellik analizden elde edilen bulgular, Türkiye’de ele alınan dönemde cari işlemler dengesi ve bütçe açığı arasında çift yönlü bir nedensellik ilişkisi olduğunu ortaya koymaktadır. Bu sonuç, Türkiye’de ikiz açık hipotezinin geçerli olduğunu ifade etmektedir. Aynı zamanda, nedensellik ilişkisinde anlamlı geçici değişimlerin olduğu gözlenmektedir. Seçim ve kriz dönemlerinde ikiz açık hipotezinin varlığı mevcut iken, 2002-2008 ve 2015-2021 dönemlerinde cari işlemler hedeflemesi politikası uygulanmaktadır. COVID-19 pandemisi döneminde ise, cari işlemler dengesi ve bütçe açığı arasında çift yönlü asimetrik aktarım mekanizmasının işlediği ifade edilebilir.
Türkiye’de Yaşam Memnuniyeti Düzeyleri: Veri Madenciliği Teknikleri ile Bir Uygulama
Authors: ÜNSAL Mehmet Çağlar , ALTAN Şenol
Published: December 2022

Yaşam memnuniyeti ve mutluluk kavramları çoğu zaman aynı anlamda kullanılır. Mutluluk kavramı, yıllar içinde bireyin kendini öznel beğenisinden, toplumdaki yerinden hoşnut olmasına veya sürdürdüğü yaşam biçiminden memnun olmasına kadar farklı şekillerde ele alınmıştır. Günümüzde mutluluk ele alınırken, bireyin kendisine özgü değerlendirmesinin ifadesi olarak, kişinin kendisini mutlu hissedip hissetmemesine daha fazla önem verilmektedir.

Bu çalışmada TÜİK tarafından yayınlanan 2016 - 2018 yılları arası Yaşam Memnuniyeti Araştırması(YMA) verileri, veri madenciliği tekniklerinden “birliktelik kuralı analizi” ile incelenmiş ve mutlu olma düzeyleri ile ilgili kurallar bulunmaya çalışılmıştır. İki aşamada gerçekleştirilen araştırmada önce YMA anket sorularından araştırmada kullanılabilecek sorular belirlenmiş, sonra da belirlenen 75 sorudan “mutluluk” ile ilgili düzeyi en fazla olan soruları belirlemek için öznitelik azaltma çalışması yapılmıştır. Yapılan çalışma sonucu “mutluluk” değişkenini en iyi açıklayan 30 soru belirlenmiştir. Belirlenen sorular ile birliktelik kuralı analizi “mutlu”, “orta derecede mutlu” ve “mutsuz” bireyler için ayrı ayrı yapılarak, bu üç durum için kurallar belirlenmiştir. Özellikle “mutlu” olma durumu için bulunan kurallar oldukça yüksek güvenilirlik düzeyindedir. Çalışmada, resmi istatistik verilerinde veri madenciliği çalışması ile faydalı sonuçlara ulaşılabileceğini, resmi istatistikler üzerinde şimdiye kadar az sayıda gerçekleştirilen birliktelik kuralı analizi çalışması ile gösterilmiştir. Ayrıca bulunan mutluluk kuralları birçok sosyal bilimciye yol gösterebileceği gibi, siyasetçilere de vatandaş memnuniyeti odaklı politika geliştirme aşamasında yol gösterici niteliktedir.
Trigonometria: conhecimento de conteúdo e de ensino fundamentados em uma revisão sistemática de literatura
Authors: Rodrigues Poliana Figueiredo Cardoso , Souza Maria Alice Veiga Ferreira de , Thiengo Edmar Reis
Published: December 2022

A Trigonometria é requisito para outros conhecimentos da Matemática e de distintas áreas da Ciência. Embora esse tema integre grande parte do currículo da escolaridade básica, para pesquisadores da Educação Matemática, pouco é efetivamente apreendido por alunos. Esse contexto motivou um estudo bibliográfico e descritivo baseado em uma revisão sistemática de literatura visando identificar: conhecimentos de professores acerca de conteúdos de Trigonometria e seus requisitos e estratégias de ensino de Trigonometria que vêm sendo implementadas na educação básica. Dez trabalhos atenderam aos critérios de inclusão e exclusão impostos pelo protocolo. Os resultados, em termos de conhecimento de conteúdo, sinalizam compreensão limitada sobre os conceitos de Trigonometria pelos professores. Quanto às estratégias de ensino, os trabalhos investigados enfatizam situações didáticas, materiais manipuláveis e recursos tecnológicos. Pela importância do tema para a comunidade escolar e acadêmico-científica, recomendamos investigações que examinem conhecimentos já existentes criando estratégias para abordagem do tema.