bluuebunny/crossref_metadata_2025 huggingface dataset:
Surface Acoustic Wave Microwave Photonic Filters in Silicon-on-Insulator with 16 and 32 Taps
Authors: Katzman Moshe , Priel Maayan , Dokhanian Leroy , Shafir Inbar , Slook Matan , Bag Saawan Kumar , Zadok Avi
Published: August 2022

Integrated, discrete time microwave filters are realized in surface acoustic wave photonic devices in standard silicon on insulator. The devices are scaled to 16 and 32 taps. A single 7 MHz-wide passband is demonstrated.
Stimulated Brillouin Scattering Microwave Photonic Notch Filter in Silicon Nitride
Authors: Botter Roel , Ye Kaixuan , Klaver Yvan , Daulay Okky , Kanger Lou , Marpaung David
Published: August 2022

We show the first all silicon nitride microwave photonic notch filter using stimulated Brillouin scattering (SBS). The filter has a rejection of more than 60 dB, a linewidth of 1 GHz, and a tunable center frequency over 1 GHz.
A free-space mm-wave photonic limiter
Authors: Kononchuk R. , Suwunnarat S. , Hilario M. S. , Baros A. E. , Hoff B. W. , Vasilyev V. , Vitebskiy I. , Kottos T. , Chabanov A. A.
Published: August 2022

Sensitive electronics must be protected from high-power microwave radiation. Here we demonstrate the first working prototype of a free-space reflective mm-wave limiter involving a nanolayer of phase-change material (vanadium dioxide) incorporated in a resonant cavity.
Photonic molecule microcombs at 50 GHz repetition rate
Authors: Rebolledo-Salgado Israel , Helgason Óskar Bjarki , Ye Zhichao , Schröder Jochen , Zelan Martin , Torres-Company Victor
Published: August 2022

We present a microcomb in a photonic molecule with 50 GHz repetition rate. The comb attains > 50% power conversion efficiency and displays a quiet point of operation in repetition rate with decreased phase noise.
Isotropic Topological Second-Order Spatial Differentiator Operating in Transmission Mode
Authors: Long Olivia Y. , Guo Cheng , Wang Haiwen , Fan Shanhui
Published: August 2022

We design a topological differentiator that operates isotropically in transmission mode at normal incidence. The device an optical transfer function with a symmetry-protected, topological charge of ±2 and performs second-order differentiation.
Nonlocal Time-Resolved Terahertz Spectroscopy in the Near Field
Authors: Pizzuto Angela , Castro-Camus Enrique , Wilson William , Choi Wonsik , Li Xiuling , Mittleman Daniel M.
Published: August 2022

We demonstrate the first “nonlocal” pump-probe measurement using a scattering scanning near-field microscopy technique by laterally displacing the pump and probe spots. We observe nonlocal effects associated with carrier drift into the probe region.
Deterministic Generation of Perfect Soliton Crystal Assisted by Saturable Absorption
Authors: Nakashima Ayata , Fujii Shun , Imamura Riku , Nagashima Keigo , Tanabe Takasumi
Published: August 2022

We found that we can deterministically generate a perfect soliton crystal by incorporating a saturable absorber in a microresonator. The crystal is generated directly from the initial Turing rolls without passing through chaos.
Stimulated Forward Brillouin Scattering from a Fundamental Acoustic Mode in a Fiber Taper
Authors: Xu Wendao , Iyer Arjun , Jin Lei , Set Sze Y. , Renninger William H.
Published: August 2022

Strong stimulated optomechanical coupling to the fundamental flexural acoustic mode of a tapered fiber is demonstrated, broadening access to frequencies, and increasing interaction-times for applications. A theoretical model featuring unique propagation dependent behavior is introduced.
Ultrabroadband mid-infrared generation in dispersion-engineered thin-film lithium niobate
Authors: Mishra Jatadhari , Jankowski Marc , Hwang Alex , Stokowski Hubert S. , McKenna Timothy P. , Langrock Carsten , Ng Edwin , Heydari David , Mabuchi Hideo , Safavi-Naeini Amir H. , Fejer M. M.
Published: August 2022

We demonstrate efficient m id-infrared d ifference-frequency g eneration in dispersion-engineered thin-film lithium niobate ridge waveguides on sapphire. These uniformly poled devices achieve phase-matching bandwidths in excess of a micron, and rapid phase-matching peak tuning with temperature.
Widely Tunable Mid-IR Optical Parametric Oscillator in Nanophotonic PPLN
Authors: Ledezma Luis , Roy Arkadev , Costa Luis , Sekine Ryoto , Gray Robert , Guo Qiushi , Nehra Rajveer , Marandi Alireza
Published: August 2022

We present on-chip optical parametric oscillators in nanophotonic periodically-poled lithium niobate, which are pumped near 1 µm and generate outputs tunable over an octave from 1.53 µm to 3.25 µm in the mid-IR.
Strong cluster synchronization in complex semiconductor laser networks with time delay signature suppression
Authors: Zhang Liyue , Pan Wei , Yan Lianshan , Luo Bin , Zou Xihua , Li Songsui
Published: August 2022

Cluster synchronization is a state where clusters of nodes inside the network exhibit isochronous synchronization. Here, we present a mechanism to realize the strong cluster synchronization in semiconductor laser (SL) networks with complex topology, where stable cluster synchronization is achieved with decreased correlation between dynamics of different clusters and time delay signature concealment. We elucidate that, with the removal of intra-coupling within clusters, the stability of cluster synchronization could be enhanced effectively, while the statistical correlation among dynamics of each cluster decreases. Moreover, it is demonstrated that the correlation between clusters can be further reduced with the introduction of dual-path injection and frequency detuning. The robustness of strong cluster synchronization on operation parameters is discussed systematically. Time delay signature in chaotic outputs of SL network is concealed simultaneously with heterogeneous inter-coupling among different clusters. Our results suggest a new approach to control the cluster synchronization in complex SL networks and may potentially lead to new network solutions for communication schemes and encryption key distribution.
Modeling and comparison of bulk and thin-film luminescent solar concentrators based on colloidal perovskite quantum dots
Authors: Zheng Zida , Zhang Yi , Cao Xiudong , Gu Gangwei , Tian Ye , Zhang Xiaowei
Published: August 2022

Photovoltaic integrated luminescent solar concentrators (LSCs) can be embedded in modern buildings to serve as power-generation units. In this Letter, we demonstrate and develop a Monte Carlo ray-tracing model and a numerical description for the performance and loss evaluation of LSCs based on colloidal quantum dots. The performance differences between bulk and thin-film LSCs are systematically analyzed at different sizes and concentrations. It is found that large-area thin-film LSCs generally perform better, which is attributed to the suppression of scattering and the retention of quantum yield by this structure with twice the performance of bulk LSCs.
Self-starting spatiotemporal mode-locking using Mamyshev regenerators
Authors: Cao Bo , Gao Chenxin , Ding Yihang , Xiao Xiaosheng , Yang Changxi , Bao Chengying
Published: August 2022

Bridging multi-mode fibers and Mamyshev regenerators holds promise for pulse energy scaling in fiber lasers. However, initialization of a multi-mode Mamyshev oscillator remains a practical challenge. Here we report self-starting spatiotemporal mode-locking (STML) in a multi-mode Mamyshev oscillator without active assistance. The first initialized mode-locking is unstable, but stable STML can be attained by increasing the filter separation. Simulations verify the capability of reaching self-starting STML using Mamyshev regenerators and unveil the effect of filter separation on the self-starting ability.
High resolution femtosecond direct laser writing with wrapped lens
Authors: Toulouse Andrea , Thiele Simon , Hirzel Kai , Schmid Michael , Weber Ksenia , Zyrianova Maria , Giessen Harald , Herkommer Alois M. , Heymann Michael
Published: August 2022

Wrapped writing mode is a simple, inexpensive approach to multiphoton stereolithography. Standard ∼10 µm thin cling foil shields the objective from direct contact with the photoresist, without compromising writing resolution. A diffraction limited lateral voxel width below 150 nm was demonstrated through ray tracing simulations and electron microscopy using standard polymer photoresist. Wrapped mode, like dip-in printing, is not limited by the objective working distance height. Its utility to prototype new print resists was validated through custom aqueous protein, silver nitrate, and black epoxy based formulations.
Graphene oxide/Ag nanoparticle/WS2 nanosheet heterostructures for surface-enhanced Raman spectroscopy
Authors: Wang Luyao , Liu Mingjin , Chen Biao , Pan Jie , Wang Shuyun , Zhang Chao , Li Zhen , Peng Qianqian , Xiu Xianwu
Published: August 2022

Combing the merits of metals and semiconductors,with superior plasmon resonance effects and high charge mobility, 3D-nanocomposite structures consisting of graphene oxide (GO), noble metal nanostructures, and two-dimensional transition metal sulfides (2D-TMDS) are an important topic in surface-enhanced Raman scattering (SERS) research. This paper presents a novel GO/Ag NPs (silver nanoparticles)/WS2 composite SERS substrate, and electric field simulation by COMSOL software. The GO/Ag/WS2 composite substrate shows very high SERS detective sensitivity and stability to probe molecules such as rhodamine 6 g (R6G), crystal violet (CV), methylene blue (MB) and deoxyribonucleic acid (DNA). The SERS sensitivity can reach 10−12 M, the relative standard deviation (RSD) is 8.24%, and the enhancement factor (EF) is approximately 6.60 × 1010 for R6G, which promoted the implementation of the SERS technique in the area of quantitative profiling and testing.
Controlling the polarization and phase of high-order harmonics with a
plasmonic metasurface
Authors: Jalil Sohail A. , Awan Kashif M. , Ali Idriss A. , Rashid Sabaa , Baxter Joshua , Korobenko Aleksey , Ernotte Guilmot , Naumov Andrei , Villeneuve David M. , Staudte André , Berini Pierre , Ramunno Lora , Vampa Giulio
Published: August 2022

Nanostructured surfaces, or metasurfaces, allow exquisite control of linear and nonlinear optical processes by reshaping the amplitude, phase, and polarization of electric and magnetic fields near wavelength-scale heterogeneities. Recently, metasurfaces have broken new ground in high-field attosecond science where they have been utilized to amplify the emission of high-order harmonics of femtosecond infrared laser pulses, a notoriously inefficient process, by enhancing the incident field, and to shape the emitted high harmonics in space. Here we show control of the polarization and phase of high harmonics with a plasmonic metasurface. We design and fabricate perpendicularly aligned rectangular gold antennas on a silicon crystal that generate circularly polarized deep-ultraviolet high harmonics, from a circularly polarized infrared driver, providing a simple path for achieving circular emission from patterned crystals. Our metasurface enhances the circularly polarized harmonics up to

∼

43

times when compared to the unpatterned surface, where harmonics are quenched. Looking forward, circularly polarized high harmonics will be useful tools for sensing chiral laser–matter interactions and magnetic materials. Our approach paves the way for polarization control at even shorter, extreme ultraviolet, wavelengths.
From kill the winner to eliminate the winner in open phage-bacteria systems
Authors: Marantos Anastasios , Mitarai Namiko , Sneppen Kim
Published: August 2022

Phages and bacteria manage to coexist and sustain ecosystems with a high diversity of strains, despite limited resources and heavy predation. This diversity can be explained by the “kill the winner” model where virulent phages predominantly prey on fast-growing bacteria and thereby suppress the competitive exclusion of slower-growing bacteria. Here we computationally investigate the robustness of these systems against invasions, where new phages or bacteria may interact with more than one of the resident strains. The resulting interaction networks were found to self-organize into a network with strongly interacting specialized predator-prey pairs, resembling that of the “kill the winner” model. Furthermore, the “kill the winner” dynamics is enforced with the occasional elimination of even the fastest-growing bacteria strains due to a phage infecting the fast and slow growers. The frequency of slower-growing strains was increased with the introduction of even a few non-diagonal interactions. Hence, phages capable of infecting multiple hosts play significant roles both in the evolution of the ecosystem by eliminating the winner and in supporting diversity by allowing slow growers to coexist with faster growers.
Nuclear Prospero allows one-division potential to neural precursors and post-mitotic status to neurons via opposite regulation of Cyclin E
Authors: Mar Jordan , Makhijani Kalpana , Flaherty Denise , Bhat Krishna Moorthi
Published: August 2022

In Drosophila embryonic CNS, the multipotential stem cells called neuroblasts (NBs) divide by self-renewing asymmetric division and generate bipotential precursors called ganglion mother cells (GMCs). GMCs divide only once to generate two distinct post-mitotic neurons. The genes and the pathways that confer a single division potential to precursor cells or how neurons become post-mitotic are unknown. It has been suggested that the homeodomain protein Prospero (Pros) when localized to the nucleus, limits the stem-cell potential of precursors. Here we show that nuclear Prospero is phosphorylated, where it binds to chromatin. In NB lineages such as MP2, or GMC lineages such as GMC4-2a, Pros allows the one-division potential, as well as the post-mitotic status of progeny neurons. These events are mediated by augmenting the expression of Cyclin E in the precursor and repressing the expression in post-mitotic neurons. Thus, in the absence of Pros, Cyclin E is downregulated in the MP2 cell. Consequently, MP2 fails to divide, instead, it differentiates into one of the two progeny neurons. In progeny cells, Pros reverses its role and augments the downregulation of Cyclin E, allowing neurons to exit the cell cycle. Thus, in older pros mutant embryos Cyclin E is upregulated in progeny cells. These results elucidate a long-standing problem of division potential of precursors and post-mitotic status of progeny cells and how fine-tuning cyclin E expression in the opposite direction controls these fundamental cellular events. This work also sheds light on the post-translational modification of Pros that determines its cytoplasmic versus nuclear localization.
Who supports science-related populism? A nationally representative survey on the prevalence and explanatory factors of populist attitudes toward science in Switzerland
Authors: Mede Niels G. , Schäfer Mike S. , Metag Julia , Klinger Kira
Published: August 2022

Science and its epistemology have been challenged byscience-related populism—a variant of populism suggesting that a virtuous “ordinary people,” and not allegedly corrupt academic elites, should determine the “production of truth.” Yet almost no studies have assessed the prevalence ofscience-related populist attitudesamong the population and explanatory factors thereof. Based on a nationally representative survey in Switzerland, our study shows that only a minority of the Swiss exhibit science-related populist attitudes. Comparisons with reference studies suggest that these attitudes may be less prevalent in Switzerland than political populist attitudes. Those who hold stronger science-related populist attitudes tend to have no university education, less personal contact with science, lower scientific literacy, and higher interest in science. Additional analyses show that left-leaning citizens are less likely to hold science-related populist attitudes than moderate and right-leaning citizens. Our findings contribute to current debates about a potential fragmentation of science communication audiences and call for further research on the sociodemographic and attitudinal profiles of people with skeptical orientations toward science.
Comparing posttraumatic growth in mothers after stillbirth or early miscarriage
Authors: Ryninks Kirsty , Wilkinson-Tough Megan , Stacey Sarah , Horsch Antje
Published: August 2022

The possibility of posttraumatic growth in the aftermath of pregnancy loss has received limited attention to date. This study investigated posttraumatic growth in mothers following stillbirth compared to early miscarriage. It was hypothesised that mothers following stillbirth will demonstrate more posttraumatic growth, challenge to assumptive beliefs, and disclosure than mothers following early miscarriage. The study also sought to understand how theoretically-derived variables of the Model of Growth in Grief (challenge to assumptive beliefs and disclosure) explained unique variance in posttraumatic growth when key factors were controlled for. One-hundred and twenty women who had experienced a stillbirth (N = 57) or early miscarriage (N = 63) within the last two to six years completed validated questionnaires in an online survey relating to posttraumatic growth and key variables relevant to emotional adjustment post-bereavement. Participants who had experienced a stillbirth demonstrated significantly higher levels of posttraumatic growth, posttraumatic stress symptoms, perinatal grief, disclosure, challenge to assumptive beliefs and rumination than participants who had experienced an early miscarriage (Cohen’sdranged .38-.94). In a hierarchical stepwise regression analysis, challenge to assumptive beliefs alone predicted 17.5% of the variance in posttraumatic growth. Intrusive and deliberate rumination predicted an additional 5.5% of variance, with urge to talk, reluctance to talk, and actual self-disclosure predicting a further 15.3%. A final model including these variables explained 47.9% of the variance in posttraumatic growth. Interventions targeting challenge to assumptive beliefs, disclosure, and rumination are likely to be clinically useful to promote psychological adjustment in mothers who have experienced stillbirth and early miscarriage.
COVID-19 market disruptions and food security: Evidence from households in rural Liberia and Malawi
Authors: Aggarwal Shilpa , Jeong Dahyeon , Kumar Naresh , Park David Sungho , Robinson Jonathan , Spearot Alan
Published: August 2022

We use data collected from panel phone surveys to document the changes in food security of households in rural Liberia and Malawi during the market disruptions associated with the COVID-19 lockdowns in 2020. We use two distinct empirical approaches in our analysis: (a) an event study around the date of the lockdowns (March to July 2020), and (b) a difference-in-differences analysis comparing the lockdown period in 2020 to the same months in 2021, in order to attempt to control for seasonality. In both countries, market activity was severely disrupted and we observe declines in expenditures. However, we find no evidence of declines in food security.
Negative emotional reactions to criticism: Perceived criticism and source affects extent of hurt and relational distancing
Authors: Neoh Michelle Jin Yee , Teng Jia Hui , Lee Albert , Setoh Peipei , Mulatti Claudio , Esposito Gianluca
Published: August 2022

Criticism is commonly perceived as hurtful and individuals may respond differently to criticism originating from different sources. However, the influence of an individual’s perception of criticism in their social relationships on negative emotional reactions to criticism has not been examined across different relational contexts. The present study investigated the influence of perceived criticism and relational contexts–mother, father, romantic partner, and workplace supervisor–on the feelings of hurt and relational distancing experienced upon receiving criticism. Participants (N = 178) completed the Perceived Criticism Measure and read vignettes describing scenarios of personally directed criticism in the four relational contexts. Significant main effects of perceived criticism and source were found on levels of relational distancing. Participants who perceived their relational partner to be more critical experienced greater distancing upon receiving criticism from them. Greater relational distancing was experienced for criticism received from workplace supervisors compared to mothers, fathers and romantic partners. Results indicate that emotional reactions and relationship outcomes in response to criticism can differ based on individual differences and relational context, suggesting their role in relationship maintenance and development of psychopathology.
SARS-CoV-2-positive patients display considerable differences in proteome diversity in urine, nasopharyngeal, gargle solution and bronchoalveolar lavage fluid samples
Authors: Okendo Javan , Musanabaganwa Clarisse , Mwangi Peter , Nyaga Martin , Onywera Harris
Published: August 2022

Proteome profile changes post-severe acute respiratory syndrome coronavirus 2 (post-SARS-CoV-2) infection in different body sites of humans remains an active scientific investigation whose solutions stand a chance of providing more information on what constitutes SARS-CoV-2 pathogenesis. While proteomics has been used to understand SARS-CoV-2 pathogenesis, there are limited data about the status of proteome profile in different human body sites infected by the SARS-CoV-2 virus. To bridge this gap, our study aims to characterize the proteins secreted in urine, bronchoalveolar lavage fluid (BALF), gargle solution, and nasopharyngeal samples and assess the proteome differences in these body samples collected from SARS-CoV-2-positive patients. We downloaded publicly available proteomic data from (https://www.ebi.ac.uk/pride/). The data we downloaded had the following identifiers: (i) PXD019423, n = 3 from Charles Tanford Protein Center in Germany. (ii) IPX0002166000, n = 15 from Beijing Proteome Research Centre, China. (iii) IPX0002429000, n = 5 from Huazhong University of Science and Technology, China, and (iv) PXD022889, n = 18 from Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905 USA. MaxQuant was used for the human peptide spectral matching using human and SARS-CoV-2 proteome database which we downloaded from the UniProt database (access date 13th October 2021). The individuals infected with SARS-CoV-2 viruses displayed a different proteome diversity from the different body sites we investigated. Overally, we identified 1809 proteins across the four sample types we compared. Urine and BALF samples had significantly more abundant SARS-CoV-2 proteins than the other body sites we compared. Urine samples had 257(33.7%) unique proteins, followed by nasopharyngeal with 250(32.8%) unique proteins. Gargle solution and BALF had 38(5%) and 73(9.6%) unique proteins respectively. Urine, gargle solution, nasopharyngeal, and bronchoalveolar lavage fluid samples have different protein diversity in individuals infected with SARS-CoV-2. Moreover, our data also demonstrated that a given body site is characterized by a unique set of proteins in SARS-CoV-2 seropositive individuals.
DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex
Authors: Hwang Bor-Jang , Gonzales Rex , Corzine Sage , Stenson Emilee , Pidugu Lakshmi , Lu A-Lien
Published: August 2022

The Rad9-Rad1-Hus1 checkpoint clamp activates the DNA damage response and promotes DNA repair. DNA loading on the central channel of the Rad9-Rad1-Hus1 complex is required to execute its biological functions. Because Rad9A has the highest DNA affinity among the three subunits, we determined the domains and functional residues of human Rad9A that are critical for DNA interaction. The N-terminal globular domain (residues 1–133) had 3.7-fold better DNA binding affinity than the C-terminal globular domain (residues 134–266) of Rad9A1-266. Rad9A1-266 binds DNA 16-, 60-, and 30-fold better than Rad9A1-133, Rad9A134-266, and Rad9A94-266, respectively, indicating that different regions cooperatively contribute to DNA binding. We show that basic residues including K11, K15, R22, K78, K220, and R223 are important for DNA binding. The reductions on DNA binding of Ala substituted mutants of these basic residues show synergistic effect and are dependent on their residential Rad9A deletion constructs. Interestingly, deletion of a loop (residues 160–163) of Rad9A94-266 weakens DNA binding activity by 4.1-fold as compared to wild-type (WT) Rad9A94-266. Cellular sensitivity to genotoxin of rad9A knockout cells is restored by expressing WT-Rad9Afull. However, rad9A knockout cells expressing Rad9A mutants defective in DNA binding are more sensitive to H2O2 as compared to cells expressing WT-Rad9Afull. Only the rad9A knockout cells expressing loop-deleted Rad9A mutant are more sensitive to hydroxyurea than cells expressing WT-Rad9A. In addition, Rad9A-DNA interaction is required for DNA damage signaling activation. Our results indicate that DNA association by Rad9A is critical for maintaining cell viability and checkpoint activation under stress.
The effects of robotic assistance on upper limb spatial muscle synergies in healthy people during planar upper-limb training
Authors: Cancrini Adriana , Baitelli Paolo , Lavit Nicora Matteo , Malosio Matteo , Pedrocchi Alessandra , Scano Alessandro
Published: August 2022

Background

Robotic rehabilitation is a commonly adopted technique used to restore motor functionality of neurological patients. However, despite promising results were achieved, the effects of human-robot interaction on human motor control and the recovery mechanisms induced with robot assistance can be further investigated even on healthy subjects before translating to clinical practice. In this study, we adopt a standard paradigm for upper-limb rehabilitation (a planar device with assistive control) with linear and challenging curvilinear trajectories to investigate the effect of the assistance in human-robot interaction in healthy people.

Methods

Ten healthy subjects were instructed to perform a large set of radial and curvilinear movements in two interaction modes: 1) free movement (subjects hold the robot handle with no assistance) and 2) assisted movement (with a force tunnel assistance paradigm). Kinematics and EMGs from representative upper-limb muscles were recorded to extract phasic muscle synergies. The free and assisted interaction modes were compared assessing the level of assistance, error, and muscle synergy comparison between the two interaction modes.

Results

It was found that in free movement error magnitude is higher than with assistance, proving that task complexity required assistance also on healthy controls. Moreover, curvilinear tasks require more assistance than standard radial paths and error is higher. Interestingly, while assistance improved task performance, we found only a slight modification of phasic synergies when comparing assisted and free movement.

Conclusions

We found that on healthy people, the effect of assistance was significant on task performance, but limited on muscle synergies. The findings of this study can find applications for assessing human-robot interaction and to design training to maximize motor recovery.
Suppression of annexin A1 and its receptor reduces herpes simplex virus 1 lethality in mice
Authors: Wang Li-Chiu , Wu Shang-Rung , Yao Hui-Wen , Ling Pin , Perng Guey-Chuen , Chiu Yen-Chi , Hsu Sheng-Min , Chen Shun-Hua
Published: August 2022

Herpes simplex virus 1 (HSV-1)-induced encephalitis is the most common cause of sporadic, fatal encephalitis in humans. HSV-1 has at least 10 different envelope glycoproteins, which can promote virus infection. The ligands for most of the envelope glycoproteins and the significance of these ligands in virus-induced encephalitis remain elusive. Here, we show that glycoprotein E (gE) binds to the cellular protein, annexin A1 (Anx-A1) to enhance infection. Anx-A1 can be detected on the surface of cells permissive for HSV-1 before infection and on virions. Suppression of Anx-A1 or its receptor, formyl peptide receptor 2 (FPR2), on the cell surface and gE or Anx-A1 on HSV-1 envelopes reduced virus binding to cells. Importantly, Anx-A1 knockout, Anx-A1 knockdown, or treatments with the FPR2 antagonist reduced the mortality and tissue viral loads of infected mice. Our results show that Anx-A1 is a novel enhancing factor of HSV-1 infection. Anx-A1-deficient mice displayed no evident physiology and behavior changes. Hence, targeting Anx-A1 and FPR2 could be a promising prophylaxis or adjuvant therapy to decrease HSV-1 lethality.
Black (metal) epics: Remediation of tradition in the case of Gavranovi from Serbia
Authors: Lajić Mihajlović Danka , Radovanović Bojana
Published: August 2022

Prompted by the emergence of Serbian black metal supergroup Gavranovi and their two singles released in 2020, this article offers an interdisciplinary and intertextual reading of this project. In this article, collaborative efforts of musicology and ethnomusicology are employed in interpreting the new readings of Serbian epic tradition in the context of extreme metal, as well as its positioning in the history of Serbian extreme metal scene in general. By using the gusle, a traditional instrument, as well as the postulates of Serbian epic poetry, Gavranovi participate in contemporary remediation of tradition, which will be examined through the lens of (inter)textual analysis.
Against the devil’s metal: Christian public discursive strategies against metal concerts and festivals in Czechia and Slovakia
Authors: Vrzal Miroslav
Published: August 2022

In the context of a process of return of religion to the public sphere, this article deals with Christian discursive strategies in public struggles against selected metal concerts and festivals since 2013 in highly secularized Czechia and in Slovakia with a close connection of religion (especially the Catholic Church) to the state. Membership categorization analysis identified three main categories used in the construction of metal as an enemy: ‘religious struggle’, ‘danger for society/state’ and ‘danger for morality and health of individuals’. Christian opponents of metal use in their discourse sets of rhetorical tactics with both religious (i.e. fight against Satan) and secular pieces (i.e. supposed extremism of some bands) to mobilize Christian community and also to attract politics and the public. In Czechia it was targeted mainly to the Christian minority and local politics, while in Slovakia religious actors were able to mobilize broader networks against metal concerts/festivals, including nation-wide politics.
Biodegradable films of arrowroot starch (Maranta arundinacea) incorporated with floral extract of Tabebuia impetiginosa and copper sulfate: physical and physicochemical properties, and biodegradability and antibacterial activities
Authors: Menezes Filho Antonio Carlos Pereira de , Ventura Matheus Vinicius Abadia , Batista-Ventura Hellen Regina Fernandes , Castro Carlos Frederico de Souza , Teixeira Marconi Batista , Taques Aparecida Sofia , Alves Ivan , Soares Frederico Antônio Loureiro
Published: August 2022

Biodegradable films of arrowroot starch were incorporated with floral extract of Tabebuia impetiginosa and copper sulfate and determined to the physical, physicochemical, biodegradability and antibacterial properties. The films were produced from arrowroot starch with different concentrations of glycerol, floral extract and copper sulfate solution. Thickness, humidity, solubility, biodegradability, water vapor colorimetry, color density, transparency, FT-IR and antibacterial activity tests were performed for Escherichia coli, Staphylococcus aureus, Salmonella serovar Thyphymurium and serovar Enteritidis. The films had a thickness between 0.23-0.33 mm, humidity between 8.53-12.22%, biodegradability between 88.98-100%, water vapor between 255.79-433.57 g m2 day, L* between 4.77-22.36; a* between -1.20 to 0.30; b* between -1.89 to 0.13; color density between -0.09 to 0.180; maximum transparency of 80%, inhibition activity between 9.13-26.26 mm for E. coli, 5.83-24.14 mm for S. aureus, 13-42-19.39 mm for S. serovar Thyphymurium, and 22.14-26.89 mm for S. serovar Enteritidis. The arrowroot biodegradable films incorporated with floral extract of Tabebuia impetiginosa and copper sulfate showed good physical, physicochemical, biodegradability and potential antibacterial activity.
Contaminação de efluentes por amoxicilina: consequências ambientais e métodos de remoção
Authors: Silva Valdemir Fonseca da , Wolff Delmira Beatriz , Carissimi Elvis
Published: August 2022

A intensificação na poluição gerada pelas atividades humanas por décadas, lançando efluentes, in natura ou parcialmente tratados nos corpos hídricos receptores, causando sérios danos ao meio ambiente. Dentre estes efluentes, os fármacos acabam trazendo uma grande preocupação, uma vez que, podem ser resistentes inclusive aos processos convencionais de tratamento, o que acaba alertando para a problemática da falta de tratamento adequado. Objetivou-se com este trabalho, realizar uma análise dos métodos de tratamento de efluentes utilizados para remoção e degradação do antibiótico do grupo β-lactâmicos, amoxicilina. Foi realizado um levantamento bibliográfico envolta de trinta e oito artigos, com uma filtragem e seleção, resultando em apenas doze trabalhos que se enquadraram nos pré-requisitos estabelecidos. Grande parte dos estudos selecionados desenvolveu suas análises em efluentes contaminados artificialmente, utilizando técnicas de adsorção, processos oxidativos avançados (POAs), wetlands, biorreator com membranas submersas, filtro de carvão ativado e hidrólise. É importante ressaltar que cada estudo, operou com técnicas bastante particulares, sendo este o principal motivo dos diferentes resultados encontrados em métodos bastante semelhantes. A análise demonstrou que dentre os métodos observados, apenas o processo tradicional de oxidação com reagente Fenton, e o método de remoção por Hidrólise Alcalina, com pH de 12,5 em 60 minutos atingiram a excelência de 100% da remoção do antibiótico. No outro extremo observou-se que a técnica de remoção do antibiótico por meio de wetlands construídos, atingiu a remoção mínima de 15% e o POA com fotólise natural em tempo de 360 minutos com remoção de 24%. Os números encontrados apontam a importância de combinar os métodos de tratamento de esgoto para alcançar uma maior pureza do efluente que será lançado no ambiente.
Avaliação da qualidade físico-química de bebidas lácteas sabor de araçá-boi (Eugenia stipitata)
Authors: Souza Patrick Gomes de , Castro Marcia Seixas de , Pantoja Lilian , Maeda Roberto Nobuyuki , Marinho Helyde Albuquerque
Published: August 2022

O fruto de araçá-boi (Eugenia stipitata McVaugh) possui acentuados aroma e acidez, atualmente é consumido na forma de suco, no norte do Brasil. Para melhores atribuições nutricionais surgiu a necessidade de formular bebida láctea fermentada de araçá-boi. Foi utilizado como constituinte da base láctea o soro de queijo, subproduto da indústria de queijos. A presente pesquisa testou três formulações com 70% de base ( nas proporções 25:75, 50:50 e 75:25, de leite fermentado e soro), 20% de polpa de fruta e 10% de açúcar. As bebidas foram avaliadas quanto ao perfil físico-químico. Todas as bebidas apresentaram perfil físico-químico dentro dos padrões da legislação brasileira para iogurtes e bebidas lácteas. A anuência do produto no mercado incentivará produtores agrícolas do norte do país a cultivarem o araçá-boi em grande escala, representado uma alternativa para o desenvolvimento sustentável da região, agregando valores ao fruto amazônico e ao soro de queijo.
Caminhos para o Novo Ensino Médio: traçando um itinerário formativo em plataforma adaptativa
Authors: Santana Aline de Abreu , Munhoz Renata Ferreira
Published: August 2022

A escola Charles Darwin Central School está se preparando para o ano de 2022 e as implantações do Novo Ensino Médio. Como professoras de Língua Portuguesa da instituição traçaram um Itinerário Formativo ligado ao eixo estruturante de “Processos Criativos" onde os alunos são envolvidos em elaborações de projetos com foco na criatividade e autonomia. Valorizando o novo formato de aula proposto pela nova BNCC e levando em consideração a presença de alunos que ainda estão assistindo às aulas no sistema on-line, desenvolver-se clínica que possibilita trabalhar a partir de habilidades individuais do aluno e explorar suas afinidades. Pensou-se, então, na utilização da plataforma adaptativa Google Classroom como media dosdora processos , geradora de dados e facilitadora de feedbacks. A trilha formativa explorou as diferentes personalidades dos alunos partindo de uma aplicação do teste de personalidade de Myers-Briggs para que todos pudessem traçar planos de estudos adaptáveis ​​às suas necessidades, vissem o seu progresso e escolhesse o próximo passo após concluir as etapas de.
Desenvolvimento de transtornos alimentares na adolescência: um estudo analítico-comportamental
Authors: Teixeira Bethania Serrão Peres , Coelho Milena Vieira , Santos Mikaele da Silva
Published: August 2022

A seguinte pesquisa teve como objetivo identificar as variáveis que influenciam no desenvolvimento dos transtornos alimentares (TA’s) no período da adolescência. Os estudos mostram que há maior prevalência destes na população feminina sendo, portanto, delimitado que as participantes da pesquisa são adolescentes do sexo feminino, com idade entre 12 e 18 anos acompanhadas no Adolescentro, Brasília, DF, Brasil, por uma equipe multiprofissional. A coleta dos dados foi realizada através de levantamento bibliográfico, estudo de prontuários e realização de entrevista estruturada contendo 25 questões com 14 adolescentes. Trata-se de um estudo descritivo e pautado em uma abordagem qualitativa, tendo seus dados analisados de acordo com a análise de conteúdo. Os resultados demonstraram que variáveis filogenéticas, ontogenéticas (vivência da adolescência, padrões comportamentais relacionados à alimentação, contextos estressores e traumáticos, satisfação com a imagem corporal e apoio social) e culturais (aspectos de gênero e influência da mídia) influenciam no desenvolvimento de transtornos alimentares, sendo que os profissionais precisam investigar as variáveis de forma detalhada sem negligenciar nenhuma delas. Conclui-se que é importante a construção de políticas públicas de prevenção aos transtornos alimentares, inserção do princípio de equidade ao se falar das diferenças de gênero e desenvolvimento de intervenções que extrapolam o contexto individual e perpassam o coletivo.
A coordenadoria de tecnologia educacional: desafios e funções
Authors: Rodrigues Lucas Ferreira , Costa Luciano Araujo da
Published: August 2022

O presente estudo, objetivou analisar a construção de uma linha de raciocínio sobre como deve ser o papel da gestão do professor responsável pela implantação e implementação de um projeto de tecnologia educacional no espaço escolar, visto que o conhecimento das diversas formas de aprender, ensinar, produzir, comunicar e reconstruir o conhecimento pode ser produzido e discutido dentro desses espaços, torna-se fundamental para a efetivação da educação cidadã. De modo a contribuir com os sujeitos envolvidos, qualificando-os para conviver em sociedade, e ainda, atuar no mundo do trabalho, conscientes de seu compromisso. No decorrer da pesquisa, foi apresentada diversas ações que devem ser desenvolvidas pelo docente no papel de coordenador de tecnologia educacional, além de seus desafios e funções, para viabilizar a implantação e implementação de um projeto inovador multimídia dentro de sua escola. Com intuito de promover a formação de docentes e discentes, objetivando incentivá-los ao uso de novas tecnologias com fins educacionais. Neste sentido, utilizamos como metodologia, a pesquisa bibliográfica referente ao uso das diversas tecnologias no ambiente escolar, que trata dessa temática a partir da problemática referente à necessidade cada vez maior, de professores com nível mais elevado de preparação e que assumam uma nova postura frente às novas demandas da atual prática pedagógica. Como resultados, constatamos a importância da função do coordenador de tecnologia educacional, que preferencialmente deve ser exercida por um professor, visto que, em função de sua vivência pedagógica e dos conhecimentos de informática onde podem ser adquiridos por meio de cursos de formação. Torna-se mais viável para ele, elaborar um projeto que atenda às necessidades da instituição de ensino sendo necessário, a priori realizar diagnóstico tecnológico da instituição que servirá como base para a execução das etapas subsequentes. Enfim, por meio do estudo realizado, justifica-se mensurar a amplitude das mudanças ocasionadas pela inserção das tecnologias de informação e comunicação, bem como, a importância do coordenador de tecnologia educacional para as instituições de ensino, nos dias de hoje.
Infestação de mosca-branca (Bemisia tabaci) em genótipos de feijoeiro (Phaseolus vulgaris)
Authors: Marques Miriam de Almeida , Millene Gomes de Souza
Published: August 2022

A mosca branca (Bemisia tabaci) é cosiderada a principal praga do feijoeiro (Phaseolus vulgaris) devido aos danos econômicos ocasionados na cultura pela intensa sucção de seiva e transmissão da virose nas plantas. Métodos preventivos de controle da mosca-branca como a resistência de planta, devem ser utilizados com o intuito de não permitir o crescimento populacional do inseto nas lavouras. Neste sentido, o objetivo desse estudo foi avaliar a infestação de ninfas e adultos de B. tabaci em diferentes genótipos de feijoeiro visando o controle da praga. O experimento foi conduzido em condições de campo na área experimental do Centro Universitário de Goiás - UNIGOIÁS. Os genótipos de feijoeiro analisados foram: BRS Estilo, BRS FC 104, BRS Rouxinol e BRS Valente. Aos dezessete, vinte e quatro, trinta e dois, trinta e nove e quarenta e cinco dias após o plantio do feijoeiro foi avaliada semanalmente o número de ninfas e adultos da mosca-branca no terço superior das plantas. Em todas as datas de avaliação, verificou-se uma maior infestação de ninfas do que de adultos de B. tabaci em todos os genótipos de feijoeiro analisados. Foi observada diferença significativa quanto à infestação de ninfas entre os genótipos analisados somente a partir da terceira data de avaliação do inseto. Quanto à infestação de adultos, os genótipos de feijoeiro se diferiram apenas na quarta data de avaliação. O genótipo de feijoeiro BRS Rouxinol foi o que mais reduziu a infestação de ninfas e adultos de Bemisia tabaci apresentando características de resistência e potencial para controlar o inseto.
Cuidados de Enfermagem às Gestantes e Puérperas Durante a Pandemia da COVID-19
Authors: Araújo Teresinha Oliveira Lima de , Bezerra Maria Eduarda Lopes de Macedo , Silva Daiane de Matos , De Souza Santos Rutiele , Araújo Taís da Silva , Santos Ana Lara Martins dos , Cruz Williane Pereira , Silva Jhayne Gislayne Lavor da , De Souza Almeida Guedes Thiemmy
Published: August 2022

A assistência de enfermagem prestada desde o pré-natal até o pós-parto é de extrema importante para evitar possíveis problemas de saúde tanto do feto, como da gestante. Contudo, com o surgimento do coronavírus, houve efeitos negativos relacionados à assistência de enfermagem prestada a esse público, principalmente em virtude do isolamento social e do medo. Com isso, esse estudo tem por objetivo verificar na literatura científica quais os impactos negativos que a pandemia trouxe na assistência de enfermagem às gestantes e puérperas. Trata-se de uma revisão integrativa da literatura realizada nas bases de dados LILACS, MEDLINE, BDENF e BVS, através dos seguintes DeCS: "Gravidez; Período pós-parto; COVID-19; Cuidados de Enfermagem"; combinados entre si pelo operador booleano AND. A busca ocorreu no mês de outubro de 2021 e foram selecionados 10 estudos para compor a revisão. Os estudos evidenciaram que há a necessidade de uma assistência de enfermagem de qualidade, a qual os profissionais devem ser devidamente qualificados para isso, para que se possa atender tanto às necessidades de bem-estar, quanto psicológicas das gestantes.
Hydnopolyporus fimbriatus (Fr.) D.A. Reid mushroom: phytochemical screening, antioxidant activity, total flavonoid and total phenolic compounds
Authors: Menezes Filho Antonio Carlos Pereira de , Ventura Matheus Vinicius Abadia , Batista-Ventura Helen Regina Fernandes , Porfiro Cinthia Alves , Teixeira Marconi Batista , Soares Frederico Antônio Loureiro , Taques Aparecida Sofia , Alves Ivan , Castro Carlos Frederico de Souza
Published: August 2022

Hydnopolyporus fimbriatus is a species of mushroom of the Meripilaceae Jülich family found in some regions of Central and South America. This study aimed to evaluate the qualitative phytochemical composition, the antioxidant activity in the reduction of DPPH and hydroxyl free radicals and to determine the flavonoid contents and total phenolics in the ethanolic extract of the mushroom H. fimbriatus. The ethanolic extract was prepared and lyophilized. Qualitative phytochemical prospection assays were performed for different groups of organic compounds. The antioxidant assay was carried out in the reduction of the 2,2-diphenyl-1-picrylhy-drazyl free radical and in the reduction of the hydroxyl free radical by colorimetric methods. The ethanolic extract of H. fimbriatus positively exhibited several phytochemical groups, moderate antioxidant activity in reducing free radical DPPH 101.09 µ mL-1, high hydroxyl radical reducing activity 87.51% and potential total phenolic content 20.15 mg GAE 100 g-1 of dry extract. Flavonoids content was not observed possibly due to the colorimetric method using aluminum chloride. With these results, it was possible to characterize the ethanolic extract of the vegetative part of Hydnopolyporus fimbriatus. New studies should be carried out in an attempt to develop a quantitative method of total flavonoids as well as test the extract in other biological models, thus being able to develop new drugs or products for agricultural use.
Effect of enzymes by substitution of corn with wheat on growth performance and digestibility of broilers
Authors: Javed Khuram , Salman Muhammad , Sharif Muhammad , Muneer Hussain , Najam Talha , Iqbal Umair
Published: August 2022

Substitution of corn with wheat associated with its variable energy content and detrimental effect on broiler performance. In a case of high-cost yellow corn, several feed producers are choosing to replace yellow corn with other ingredients like wheat, barley or sorghum. The predominant Non Starch Polysaccharides (NSP) in wheat are the pentosans (arabinixylans).  Nonstarch polysaccharides create a viscous environment in the gastrointestinal tract of broiler chickens thereby interfering with the digestion and absorption of nutrients. Broilers lack endogenous enzymes to degrade arbino-xylans of wheat. Supplementation of exogenous feed grade enzymes to the cereal based diets improve the performance of broilers. Enzyme supplementation of chicken cereals based diets has resulted in improved starch and nitrogen digestibility as well as improved absorption of starch, amino acids and lipids. Supplemental enzymes such as β-glucanase, xylanase, protease and amylase break the polymeric chains of NSP into smaller pieces, thereby improving their nutritional value. The study concluded that the supplementation of NSP-degrading enzymes in wheat-based diet improve growth performance, ileal viscosity and gastric passage rate in broiler chickens.