bluuebunny/crossref_metadata_2025 huggingface dataset:
Diseño industrial y ollas comunitarias
Authors: Guazá Lasso Valeria
Published: December 2023

Estudiantes de Diseño Industrial de la Universidad Autónoma de Occidente colaboraron en un proyecto de Diseño Social para mejorar las ollas comunitarias en Cali, específicamente en el barrio Omar Torrijos. Trabajando con la Fundación Aprender, crear y crecer, dirigida por Ingrid Campas Mina, el equipo se enfrentó a la falta de seguridad alimentaria en un contexto de pobreza. El diseño de una base para las ollas comunitarias fue crucial para resolver problemas como la inestabilidad y riesgos asociados con las estructuras improvisadas. El proyecto involucró escucha activa, análisis y síntesis, y co-diseño con la comunidad, resultando en la creación de la base VEA, que busca mejorar la comodidad y seguridad en la preparación de alimentos. La experiencia destaca los desafíos y aprendizajes al aplicar el Diseño Social en contextos reales, subrayando la importancia de considerar las necesidades y la participación activa de la comunidad en el proceso de diseño.
Cultivando una nueva sociedad
Authors: Navia Paula
Published: December 2023

En el proyecto "Cultivando una nueva sociedad", estudiantes de Diseño Industrial intervienen en el barrio Poblado II de Cali, abordando problemáticas de microtráfico, violencia juvenil y pobreza mediante una huerta urbana. La iniciativa, liderada por la Fundación Fundautónoma, busca fortalecer el tejido social y ofrecer alternativas a los jóvenes. Se enfrentan a desafíos como la disciplina y mantenimiento de la huerta. A través de talleres participativos, los estudiantes diseñan "OrganiHuerta", un organizador ecológico para herramientas y semillas. La elección del diseño final incorpora aspectos observados durante el proceso, promoviendo la participación y la sostenibilidad.
Analysis of the Impact of Age and Regional Characteristics on Population Change: Focusing on the Resident Population Census from 2009 to 2020
Authors:   Korea Real Estate Policy Association, Joo Hyun-Tae
Published: December 2023

According to the population projections by Statistics Korea, the working-age population is expected to decline by over 3.5 million people from its peak in 2019 to 2030. Additionally, Republic of Korea has the lowest total fertility rate of 0.84 births per woman among OECD countries. The population decline in Korea is a significant challenge accompanied by population aging. However, there are some regions in the metropolitan area where population growth is observed. In this study, we aim to identify the key factors influencing population change using machine learning analysis. The factors consider include population composition by age group and various social factors such as employment, housing, culture, health-care, and welfare at the community level. The analysis results show that changes in population size in the age groups of 50∼54 and 45∼50 had a high degree of influence on the change in the population of the region. These age groups have a high proportion in the population composition of Korea and are associated with active economic activities in the working-age population. On the other hand, age groups with older individuals have less influence on population change. In terms of regional characteristics, the analysis reveals that the supply of housing, particularly apartments, had a strong impact on population change. The availability of apartments indicates not only increases housing supply but also the development of convenient facilities and job creation. Rental prices are found to have a negative influence, while property prices have a positive influence on population change. Although this study aims to examine multiple factors affecting population change, further analysis based on regional characteristics and typologies could yield more improved research outcomes.
Presentazione
Authors: Pinto Giuliano
Published: December 2023

Il breve scritto rende conto degli eventi che, a partire dalla riedizione del 1999 degli Statuti del Comune fiorentino del 1322-25, hanno condotto all’edizione, nel 2023.
Gli Statuti della Repubblica fiorentina del 1355. Un monumento della cultura politica cittadina nell’Italia del Trecento
Authors: Salvestrini Francesco
Published: December 2023

Il contributo prende spunto dalla recente edizione degli Statuti in volgare della Repubblica fiorentina del 1355 per proporre alcune considerazioni sulla normativa statutaria cittadina quale strumento di affermazione politica e identitaria delle istituzioni comunali. Il saggio evidenzia come la grande silloge normativa presa in esame costituisca un vero e proprio ‘monumento’ della cultura giuridica locale e ne sottolinea il significato soprattutto come fonte per la storia della società, delle istituzioni e della lingua locali nel pieno secolo XIV.
Relación entre ejercicio físico, variables mediadoras y adicción al smartphone en estudiantes: revisión narrativa
Authors: Prieto Andreu Joel Manuel
Published: December 2023

Introducción: la adicción a los smartphones está asociada a efectos negativos en la salud psicofísica y el bienestar social. La actividad físico-deportiva y la adicción a los smartphones se consideran dos variables independientes pero interrelacionadas desde el punto de vista de la salud. Se ha explorado su posible conexión planteando como hipótesis que la actividad físico-deportiva, el ejercicio físico o la participación en deportes pueden utilizarse como una estrategia de intervención para tratar esta adicción. Se plantea como objetivo realizar una revisión narrativa de la literatura sobre las relaciones entre la actividad físico-deportiva o la participación en deportes, las variables mediadoras y la adicción a los smartphones en la población estudiantil. Metodología: se llevó a cabo una búsqueda en las principales bases de datos de investigación: Web of Science (WoS) y Scopus, para encontrar la literatura relevante sobre las relaciones entre la adicción al uso del smartphone y la práctica de ejercicio físico. Resultados y discusión: los resultados sugieren que, a medida que aumenta la adicción al smartphone, disminuye el nivel de actividad físico-deportiva en los estudiantes. Se discuten los resultados sobre inactividad físico-deportiva, variables mediadoras, adicciones, percepciones y habilidades psicológicas, así como se plantean pautas para prevenir la adicción a los smartphones en los estudiantes adolescentes. Conclusiones: la adicción a los smartphones puede reducirse aumentando la participación en actividad físico-deportiva entre los estudiantes. Las instituciones educativas pueden utilizar el deporte y el ejercicio como estrategia de intervención para hacer frente a la adicción a los smartphones en la población estudiantil.
The concept of public appeals as a sign of the objective side of the illegal act
Authors: Глуздак Г.Н. , Булгакова Л.С.
Published: December 2023

В статье исследуется содержание понятия публичных призывов как признака административных правонарушений и преступлений, предусмотренных рядом статей КоАП РФ и УК РФ соответственно. Рассматривается соотношение данного термина с категориями «публичные действия», «пропаганда», «склонение», «подстрекательство». Делается вывод о том, что публичные призывы являются разновидностью, вербальной формой публичных действий. Формулируется авторское определение публичных призывов как побудительного обращения, выраженного в словесной форме любым способом (устным, письменным, с использованием технических средств или иным) и адресованного неопределённому кругу лиц. Отмечается необходимость внесения в КоАП РФ и УК РФ дефинитивных примечаний, которые бы раскрывали смысл данного понятия.

The article researches the content of the concept of public appeals as a sign of administrative offences and crimes provided for by a number of articles of the Code of Administrative Offences of the Russian Federation and the Criminal Code of the Russian Federation, respectively. The correlation of this term with the categories “public actions”, “propaganda”, “declension”, and “incitement” is considered. It is concluded that public appeals are a kind, a verbal form of public actions. The author's definition of public appeals is formulated as an incentive appeal expressed verbally in any way (oral, written, using technical means or otherwise) and addressed to an indefinite circle of persons. It is noted that it is necessary to make definitive notes to the Code of Administrative Offences of the Russian Federation and the Criminal Code of the Russian Federation that would reveal the meaning of this term.
The axiom of choice and its applications: An exploration of the '100 prisoners problem'
Authors: Chen Shuyan
Published: December 2023

The Axiom of Choice (AC), a cardinal principle in set theory, postulates that for any assortment of disjoint non-empty sets, its possible to construct a new set by selecting one element from each set in the collection. Using choice functions, this idea suggests that every collection of nonempty sets can be associated with a choice function. In the mathematical landscape, ACs significance is accentuated by its extensive application in a myriad of mathematical deductions, marking it as a cornerstone among mathematical axioms. This study delves into the practical implications and applications of AC, employing rigorous analytical methods to investigate its vast and multifaceted influence on the broader mathematical domain. Key findings indicate that AC has facilitated the proof of various theorems, some of which, on the surface, appear unrelated. While its inception sparked considerable debates due to concerns over its intuitive validity, its impact on contemporary mathematics is profound. This research underscores ACs central role in advancing mathematical thought, highlighting its contributions to both foundational theories and intricate proofs.
Challenges to aviation in the global warming context
Authors: Fan Qiwei
Published: December 2023

The aviation sector has undergone substantial growth, leading to a corresponding increase in emissions attributed to this industry. This escalation in emissions has notably contributed to the intensification of global warming. This research provides a comprehensive examination of various prospective solutions to mitigate these emissions. Among the proposed solutions is the adoption of an intercooled turbofan engine. This specific engine type holds the promise of realizing a 3.1% reduction in fuel consumption compared to traditional engines. Furthermore, the incorporation of a recuperator in an intercooled turbofan engine could potentially lead to a significant decrease in fuel consumption by up to 30%, alongside a remarkable 20% improvement in engine efficiency. The discourse also extends to the subject of hydrogen-powered aviation, underscoring its substantial potential in achieving emissions reduction goals. However, the associated challenges, especially those related to hydrogen storage, are also explored in this study. The forthcoming era of jet engine technology may witness the amalgamation of intercooled turbofan engines and hydrogen energy sources as a viable pathway for substantial emissions reduction.
Optimization and improvement of voltage mode band-gap reference circuit and current mode band-gap reference circuit based on comparative analysis method
Authors: Zhou Yang , Zhang Sitao , Chen Chongyi
Published: December 2023

Voltage mode band-gap reference source and current mode band-gap reference source is the basic unit of integrated circuit, which plays an important role in some circuit systems such as low-voltage linear regulator, power control chip and analog-to-digital/analog-to-digital converter. Band-gap reference circuit is divided into voltage mode band-gap reference circuit and current mode band-gap reference circuit, and their basic principles and optimization methods are different. The voltage mode bandgap reference voltage is generated by superimposing voltages with positive and negative temperature coefficients, thereby producing a low-temperature related factor. In contrast, the current mode bandgap reference generates a reference voltage by superimposing currents with positive and negative temperature coefficients, requiring appropriate resistance matching and compensation. This paper analyzes the basic principles of the above two band-gap reference circuits, analyzes the temperature characteristics and mismatch sources of them, compares the research results including the implementation mode, temperature characteristics, application range and optimization scheme of the two, and looks forward to the future development prospect of both types of circuits.
The quantum tunnelling effect in double barrier structure
Authors: Wang Zichen
Published: December 2023

The purpose of this paper is to study the quantum tunnelling effect of double barriers. At the beginning, the research background and application of quantum tunnelling effect are described, and then the research purpose is explained. Although the real double barriers are very complex, most of them are composed of double barrier, double triangle barrier and double parabola barrier. The author mainly studies the barrier of double parabola. The reason is that the quantum tunnelling effect proposed by Hund will greatly adjust the internal structure of triangular conical molecules, which has great research significance. In triangular conical molecules, the change of potential energy of a single atom with its position may be very complicated, but the part that can occur with the consequential effect is similar to the potential barrier of a double parabola. In this paper, the wave function, projection and reflection coefficients of the biparabolic barrier tunnelling effect are analysed to determine whether it has a great adjustment effect on triangular conical molecules.
Transmission coefficient in double barrier quantum tunnelling effect
Authors: Duan Zhongzheng , Luo Wenxi , Xu Xiaohan
Published: December 2023

At the turn of the twentieth century, the establishment of quantum theory propelled rapid advancements, particularly in the understanding of quantum tunnellinga fundamental phenomenon in quantum mechanics crucial for various physical processes. The quantum phenomenon of particle passes through potential barriers is of great importance. In classical physics, when the energy of a particle is less than the height of a double barrier structure, it is impossible for it to pass through. However, quantum mechanics allows a particle to penetrate the barrier and emerge on the other side. This paper explores the quantum tunnelling effect, focusing on the single potential barrier model in one dimension and subsequently extending to the double potential barrier model. The Schrdinger equation provides the foundational framework for elucidating the motion of microscopic particles, emphasizing wave-particle duality inherent in quantum mechanics. The analysis of the single potential barrier model involves solving the Schrdinger equation in different regions, determining wave functions and coefficients through boundary conditions. The transmission coefficient is derived, representing the probability of a particle passing through a barrier. In the case of a thick barrier, an approximate form for transmission coefficient is provided, demonstrating the exponential decrease in transmission probability with increasing barrier thickness.
Comparative analysis of different machine learning models for predicting Google stock price
Authors: Wang Kejia
Published: December 2023

With an increasing reliance on data-driven decision-making in the business world, the need for accurate stock price predictions has grown substantially. This paper aims to address this crucial aspect, aligning machine learning methodologies with real-world business applications. The dynamic nature of financial markets indicates that it is characterized by intricate price movements influenced by an array of factors. Because it has the ability to reveal patterns and relationships in the data that traditional research can miss, machine learning has attracted a lot of attention in this context when it comes to predicting stock values. Methodologically, this paper applies three popular machine learning models to predict Google's stock prices. Linear Regression, Decision Tree, and Random Forest are each employed to assess their predictive accuracy and reliability. Metrics such as Root Mean Squared Error (RMSE), R-squared, Mean Absolute Error (MAE), and Residual Analysis are used to evaluate the models' performance. The findings reveal that Linear Regression outperformed the other models in predicting Google's stock prices. Its superior performance, as indicated by the evaluation metrics, suggests that it may be a valuable tool in the realm of financial forecasting. These findings highlight how data-driven insights can improve company strategy and decision-making, and they have important ramifications for the use of machine learning in stock market analysis.
Hydrogen energyOne of the best solutions under the background of energy saving
Authors: Qian Duan
Published: December 2023

As the new energy cars are more and more welcome by the society and Chinese government supporting for hydrogen energy continues to increase, those company such as TESLA and BYD, two typical electronic car producer, are taking the main part of family use cars. In the future, hydrogen energy batteries will be put into all aspects of life, and it will also play an important role in the development of new energy. Making full use of hydrogen fuel cell plays an important role in promoting Chinas national defence science and technology and economic life. Under the impetus of FCH JU, the EU is preparing to enter the market on a large scale and accelerate the implementation of demonstration operation projects. At the same time, the large-scale use of hydrogen fuel cells brings less carbon emissions to the EU, and energy efficiency will increase by 27% in the next 10 years.
Research on the development and risks of large language models
Authors: An Haoyuan
Published: December 2023

Large Language Model (LLM) has great potential and wide application prospects, including improving the degree of intelligence, improving production efficiency, and providing diverse solutions for enterprises, governments, individuals, etc. If the problem of computing power can be overcome, it will have unlimited potential. It has attracted wide attention in the fields of Natural Language Processing (NLP) and Artificial General Intelligent (AGI). However, with the expansion of the scale and capabilities of large language models comes a series of potential risks and challenges. This paper reviews the development and risks of large language models in different research fileds. In the future, with the improvement of algorithms, personalized solutions can be developed more efficiently for service, and social productivity can be improved. However, it is also necessary to strengthen the regulatory review of the output of large language models and the correction of data bias to ensure the accuracy of the research content.
Prediction of tumor growth at the microscopic level through mathematical modeling
Authors: Jiang Yu
Published: December 2023

All articles must contain an abstract. The abstract text should be formatted using 10 point Times or Times New Roman and indented 25 mm from the left margin. Set the pre-paragraph to 0 pounds and the post-break to 22.7 pounds. Starting on the same page as the abstract. The abstract should give readers concise information about the content of the article and indicate the main results obtained and conclusions drawn. The abstract is not part of the text and should be complete in itself; no table numbers, figure numbers, references or displayed mathematical expressions should be included. It should be suitable for direct inclusion in abstracting services and should not normally exceed 200 words in a single paragraph. Since contemporary information-retrieval systems rely heavily on the content of titles and abstracts to identify relevant articles in literature searches, great care should be taken in constructing both. To gain valuable insights into the growth of microscopic tumors, which is crucial for advancing cancer research, scientists employ mathematical modeling techniques. These models help researchers to comprehend how cells interact, proliferate, and organize spatially within tumors, ultimately aiding in developing better treatment strategies, including personalized medicine. A recent study introduced a novel approach using the Occam Plausibility Algorithm (OPAL) for modeling tumor growth. OPAL is a probabilistic framework adept at generating and refining hypotheses based on complex datasets. In this study, researchers integrated two existing models, the Proliferation Invasion Model (PIM) and the Mathematical Phase Field Model (MPFM), to create a comprehensive understanding of microscopic tumor growth dynamics. In this research, we have employed a literature review methodology to explore how researchers utilize three various mathematical modeling techniques, including the Occam Plausibility Algorithm (OPAL), to delve deeply into the growth dynamics of microscopic tumors. The conclusions drawn emphasize the significant potential of mathematical modeling in advancing scientists understanding of microscopic tumor growth.
Application of BIM in project management in China
Authors: Liu Xi
Published: December 2023

As a nation that is quickly developing, Chinas construction industry faces a variety of issues. Despite the size and technical complexity of some Chinese projects, the old paper documents and two-dimensional drawing techniques are no longer adequate to meet demand. Chinas construction sector has enormous potential. Therefore, effective digital technology and the best project management are crucial for the growth of Chinas construction business. Throughout the whole life cycle of a construction project, including all phases of planning, design, building, operation, and maintenance, Building Information Modelling (BIM) can be used. This study intends to investigate the use of BIM in project management in China with a particular emphasis on how BIM impacts project design, construction, and operation. By analysing the successful cases of BIM in Chinas project management, the prospect and development of BIM in Chinas construction industry are discussed. In the whole process of project management, BIM improves quality, efficiency, sustainability and maintainability through various applications. It is intended to provide Chinas construction industry with a tool to promote the modernization and long-term growth of the industry.
Comparative analysis of logic gates based on CMOS, FINFET, and CNFET: Characteristics and simulation insights
Authors: Zhang Yichen
Published: December 2023

In the evolution of integrated circuit technology, chip size and performance enhancement stand as paramount and challenging domains of progress. Yet, a dearth of foundational simulations and comparisons for introductory purposes exists. Consequently, this study delves into an introduction of distinct advanced integrated circuit (IC) technologies: CMOS, FinFET, and CNTFET, dissecting their merits and limitations. Subsequently, a preliminary simulation is executed to authenticate specific characteristics inherent to these IC technologies. Discoveries indicate that as IC transistors scale down, there are marked improvements in transistor performance, encompassing aspects such as switching speed, noise immunity, power efficiency, and heat dissipation. Further, a simulation grounded on a NAND gate substantiates certain traits in CMOS and FinFET, specifically switching speed, propagation delay, and noise margin. The results illustrate a superior performance of FinFET over CMOS. Additionally, as CMOS technology scales, its efficacy enhances. Nonetheless, the present research and simulations hold potential uncertainties and constraints, paving avenues for more refined investigations in the future.
Land use structure optimization in Los Angeles County based on grey linear programming
Authors: Li Tianyu
Published: December 2023

In the rapidly developing modern world, population growth and urbanization have driven the prioritization of industrial settlements over the natural environment in land use. Besides losing ecological services, many inherent problems emerge in cities due to inefficient planning. This study presents an application of a grey linear program to maximize the socio-economic and environmental benefits of the land use structure in Los Angeles County. A technique in operations research, linear programming fits the purpose of this study since it optimizes a function concerning constraints. For each of the fourteen land types in this research, a monetary value is assigned to its economic output and environmental services, and the scalar sum is the goal to be maximized. The constraints consist of inequalities built from historical trends, developmental needs, and targets. On the other hand, based on past data, the grey model employs differential equations to predict the value of several parameters for the linear program, such as GDP output. The results are calculated by the Scipy library in a Python program and improve the quantified benefit by 8.26%, with an increase in residential, commercial, and industrial land and a slower decrease in natural landscape. Environmental initiatives and improvements in LA Countys livability are necessary to fulfill long-term values.
A study of factors influencing first-year students' adaptation to blended learning
Authors: Yi Haiwen
Published: December 2023

Blended learning has become an indispensable learning way in universities, and study adaptation is a key indicator for determining learning quality. This paper compiles scales of blended learning adaptation and influencing factors for first-year students on the basis of survey research to explore the influencing mechanism of blended learning adaptability. The results show that the blended learning adaptability is at a moderately high level, but there are significant differences in terms of sex and course frequency. Female students are significantly higher than male students, and students who participate in learning 8-12 times and more 12 times per month are significantly higher than those with low frequency of learning courses in terms of online learning, learning environment, and overall study adaptation. In terms of influencing factors, motivation, academic self-efficacy and learning platform have a direct positive and significant effect on blended learning adaptation, while instructor teaching and online course content dont have a direct positive and significant influence.
From learning with errors (LWE) problem to CLWE problem
Authors: Zhao Jiankai
Published: December 2023

The main purpose of this paper is to introduce the learning with errors problem on cyclic algebras, i.e., the CLWE problem, and to fully discuss and utilize the well-proven LWE-related conclusions and assumptions in cryptography theory. Firstly, this paper provides the basic framework of Learning with Errors (LWE) problems for cyclic algebra samples. Then lattices generated by the two-sided ideal of cyclic algebra with natural order are applied to cryptography. Based on the above contents, the so-called CLWE problem is introduced to point out the dimensions and structures suitable for constructing cryptographic systems for explicit algebra, and the security of corroding problems is discussed in the CLWE samples. Finally, this paper also discusses some possible future research directions, some natural routes to further research the construction and application of CLWE problems, for example, how to choose parameters for a specific security level, so as to offer some references for future study.
Bacteria mediated cancer treatment (BMCT) and quorum sensing system in BMCT
Authors: Diao Xiaohan
Published: December 2023

Many treatments against cancer already exist. For example, radiation therapy, chemical therapy and immunotherapy, combined the physical surgery, these treatments do make a remarkable effect in inhibiting the growth of the tumor and thus prolonging the patients life. However, most of the treatments mentioned above would simultaneously damage normal cells and cause trauma or pain to the patients. In recent years, researchers have turned their attention to the remarkable natural abilities of certain bacteria such as Salmonella and E. coli, in suppressing malignant cells and solid tumors. Bacteria-mediated cancer treatment (BMCT) has emerged as a promising approach that offers the potential for reduced patient trauma and enhanced precision in targeting cancerous tissues. Furthermore, the integration of quorum sensing systems, initially utilized in the fermentation process holds promise in augmenting the navigational capabilities of bacteria. This advance opens the door to the development of highly location-sensitive bio-agents capable of delivering substantial quantities of specific therapeutic proteins directly to tumor sites. This review aims to comprehensively examine existing BMCT methodologies and explore the quorum sensing pathways that have been identified. Additionally, it contemplates the feasibility of synergizing these two systems to offer a novel perspective on cancer treatment.
Regulatory effects and clinical application of panax-based compound formula on chronic diseases
Authors: Li Yu
Published: December 2023

Hypertension, diabetes, and hyperlipidemia are common chronic diseases today and can lead to severe complications. Panax-based compound formula, as a comprehensive traditional Chinese medicine formulation, incorporates various components such as Panax, exerting multiple pharmacological effects, including nourishing the kidney qi, strengthening the heart, vasodilation, and increasing blood flow. Through the study of multiple cases, including patients with hypotension, heart disease, diabetes, hyperlipidemia, as well as early and long-term hypertension, preliminary evidence has been provided, indicating the potential positive effects of this compound in different types of hypertensive and diabetic patients. It demonstrates clear antiarrhythmic effects and effectively reduces blood pressure, improves heart failure, and alleviates hyperlipidemia. However, further research and clinical trials are required to verify its long-term therapeutic effects and safety. It is crucial to develop personalized treatment plans when using this compound formula.
Cohort analysis for the present mutation of NPM1 in bone marrow cancer
Authors: Wang Jing
Published: December 2023

DNA is the most important code for deciphering human genetic information. It finally determines proteins through the central dogma. Therefore, gene mutations can cause various diseases. Cancer is one of the most difficult-to-cure diseases caused by mutations. Acute myeloid leukemia is one of the subtypes of bone marrow cancer, this essay will predominantly focus on the study of the mutation gene NPM1 (nucleophosmin 1). In order to understand the differences between the mutated gene NPM1 and other mutated genes, a cohort study analysis of NPM1 is needed. This research helps better understanding of cancer and the variation of NPM1 compared to the others. By researching and analyzing direct clinical data, this essay will contribute to the understanding of cancer and help turn a scientific blank message into a more simple and understandable manner. However, the limitation of this study is insufficient or even missing data. With the development of research and the improvement of data, future studies will be more accurate and effective, providing a more effective reference for exploring targeted therapy of acute myeloid leukemia.
Antiviral research and detecting viral nucleic acids based on the CRISPR-Cas technology
Authors: Li Peizhe
Published: December 2023

Viruses constructed from nucleic acids, either deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), are encased in a protein covering and require a living cell to reproduce. Symptoms of viral infections can range from asymptomatic to severe illness, and their impact has become increasingly apparent in recent years. For instance, globally, the Corona Virus Disease 2019 (COVID-19) epidemic alone has resulted in millions of infections and millions of fatalities. Consequently, the development of effective tools for antiviral resistance is an urgent need. Early detection of viral infections can be achieved through nucleic acid detection, while gene editing techniques offer a promising solution for treating and counteracting the harmful effects of viruses, thereby minimizing economic and property loss. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and associated (CRISPR-associated, Cas) protein system (CRISPR-Cas) is an emerging gene editing tool that has demonstrated remarkable accuracy and efficiency with its rapidly expanding applications. This review delves into the principles and applications of Cas12a, Cas13, and other systems in nucleic acid detection, highlighting the significant contributions of Cas9, Cas12a, Cas13, and other systems in establishing resistance against DNA and/or RNA viral infections, and outlines the strengths and limitations of the CRISPR-Cas system in current applications. Precautions and suggestions for the systems safe application are also presented, with an optimistic outlook for its prospects.
The prospects of targeting ferroptosis in cancer therapy
Authors: Yuan Yongsheng
Published: December 2023

Ferroptosis represents a unique form of cell demise within the cellular framework, characterized by its reliance on intracellular iron levels, distinguishing it from apoptosis, necrosis, and autophagy. Emerging research indicates ferroptosis can restrict tumor growth, revealing potential new avenues for novel cancer treatments. The ability of ferroptosis to impede cancer cell proliferation highlights its promise as an innovative anti-tumor strategy. The fate of the cell is ultimately determined by the cellular machinery that governs ferroptosis. This central regulatory hub meticulously assesses the diverse pro-survival and pro-death cues it receives from subcellular organelles before making the determination of whether to initiate ferroptosis. This summarizes current knowledge about the regulatory mechanisms of ferroptosis, the crosstalk between apoptosis and ferroptosis, and the relationship between ferroptosis and specific organelles. Finally, some examples of drugs related to this topic are also discussed.
Role of digital epidemiological technologies in controlling COVID-19: Cases review
Authors: Wang Xiaoyang
Published: December 2023

The pandemic of COVID-19 had not only been testing the existing health care system globally, but also highlighting the need for more innovative and adaptive methods in dealing with new health threats. Digital technology become one of the most effective and efficient strategies in terms of controlling and monitoring the outbreak of this disease. These digital strategies will serve a significant role in providing valuable insights in disease and virus control for any upcoming event. This paper aims to discuss and evaluate the roles of digital technology methods in addressing COVID-19 pandemic, while focusing primarily on two case studies: COVIDSafe App from Australia and the EUs Digital COVID Certificate. While confronting the challenge raised by COVID-19, the world had invented critical digital tools as instruments to monitor, track, and manage the spread of virus. By taking a deeper look at the history, technology, and application of the successful cases, the author hopes to draw important lessons from these experiences, and foreshadowing some broader potentials for their future development and usage. Additionally, the author also analyzes the legal and privacy concerns that may come with the adaption of digital technology in fighting the pandemic, and underscore the implication of technological methods advancement for future health crisis.
The influenza viruses in China: Pandemic and prevention measures
Authors: Du Yifei
Published: December 2023

Seasonal influenza (SI) is a kind of respiratory virus with annual epidemic and high contagion, leading to cause increased morbidity and mortality in certain population. According to estimates, the flu causes an average of 400,000 respiratory deaths per year worldwide. The estimate mortality of flu is more than 65 per 100,000 people in the worldwide, and the ratio is 52.9/100,000 in China, demonstrating that seasonal influenza has caused a considerable disease burden in China. Influenza viruses are spread by droplets, and people infected with seasonal influenza usually have a sudden high fever, dry cough, and severe headache. Noteworthy, children and gravidas have higher rates of infection, and the elder population over 65 ages has a higher risks for complications, hospitalizations and death, especially patients with cardiovascular and pulmonary diseases. Therefore, prevention and treatment of high-risk populations is important to prevent and control influenza, while vaccination is an effective solution to protect them from infection and associated complications. In this paper, the author analyzes the epidemic features of influenza viruses in different regions of China in light of the prevention and control policies in various places, and provides some suggestions to prevent pandemic of influenza virus and enhance individuals preventive awareness, which purpose is to reduce the influenza positivity rate and the infection rate in the future, especially for vulnerable population of children and elder people.
The effectiveness and persistence of LTP on synaptic plasticity during sleep and sleep deprivation
Authors: Zhuang Yan
Published: December 2023

The synaptic strength, which is crucial for memory and cognition function, is significantly influenced by sleep. According to earlier research, sound sleep is crucial for promoting connections between neural networks that are necessary for memory consolidation in the hippocampus. On the other hand, sleep deprivation can seriously impair the plasticity of our synapses. Sleep deprivation will disrupt LTP in region CA1 of the hippocampus, causing damage to neural connections. LTP has been proven to improve the connection between synapses, which will promote synaptic plasticity and so influence cognition function favorably. We also take a deeper look at LTP from a cellular and genetic perspective. In this review, we explore the detrimental effects of sleep deprivation on LTP stimulation and how they weaken synaptic plasticity and impair memory and learning performance. By studying LTP we can unravel the mysteries of brain function and the ability to learn and memory, and it can also give implications for understanding neurological disorders and advancing our knowledge of neurol system.
Civilizational dissent at late 1990’s: body, fashion and club cultures in contemporary society
Authors: Guerra Paula , Figueredo Henrique Grimaldi
Published: December 2023

British fashion of the 1990s manifests a fin-de-siècle social anxiety. Facing a systemic crisis of culture, some designers embodied the sociological concepts of risk and carnivalization in their creations. This attitude is reflected in the emergence of themes such as the wasted look and abject aesthetics, epistemological solutions arising from a legacy of grunge experiences. Based on a documental approach, materialized in media and art works, to some British fashion shows of the 1990s, we will discuss in this article several aspects of the relationships between body, risk, carnival and fashion, focusing on the works of British designers and its manifestation in the hidden economies (club cultures scenes included), in which Alexander McQueen played a central role.
Scoring Loss in a Contemporary New Zealand Musical
Authors: Braae Nick , Sidwell David , Mayall Jeremy , Chuen Kyle
Published: December 2023

This paper functions as an exegesis of a recent New Zealand musical, Mum’s Kitchen. The show was a creative practice research project and involved a collaborative writing/composition process with a team of four creatives. The article explores explore the confluence of musical voices within the work with a focus on the distinct musical choices made in relation to particular narrative themes. Taking a cue from Murphy (2014), we analyse the songs in Mum’s Kitchen that directly express loss and nostalgia. We suggest that the two composers have their own strategies for “scoring” this theme: use of “anachronistic” styles (such as a country ballad) to evoke a past era, and a collection of contemporary harmonic devices (open chord voicings, harmonic ambiguity) that evoke emptiness and uncertainty. We then argue that [author] as orchestrator both unified these voices through a consistent sound palette, while also emphasising these themes through his sonic choices.
Artistic Research in Popular Music: A Critical Evaluation of Potentials and Challenges
Authors: Zaddach Wolf-Georg
Published: December 2023

The article discusses artistic research as a new paradigm. For this purpose, a contextualizing analysis on practice research is first conducted. Thereby, the essential points of criticism and potentials of artistic research are elaborated from the point of view of epistemic injustice and decolonizing approaches. Following on from this, artistic research is discussed as a promising approach to research and teaching in popular music. Topics and perspectives are suggested, and ultimately a call is made for collaborative research to develop a ‘mosaic epistemology’ and ‘epistemological pluralism’.
Learning Music for Fun, Not Credit
Authors: Sykes Tom
Published: December 2023

This article is a critical reflection of a small, practice-based project involving a university big band. Music was written specially for the project by the author, who is the band director, and this big band is an extra-curricular ensemble made up of both students and musicians from the local community. The project uses an Artistic Research approach, in which insights are gained through the practice and for which the artistic artefacts (in this case two pieces of music) form a significant part of the research. After the performances some of the band members were interviewed about their experience of the project and other aspects of playing in the band. Artistic Research is an increasingly used practice-based method in jazz research and there is scope for it to be utilized more widely in popular music.
#DancingIsNotACrime: Dance as Digital Resistance in the Transnational 21st Century
Authors: Smith Christopher J
Published: December 2023

In a live video posted to YouTube Sept 2 2014, a young woman, dressed in black and standing on a stationary car, dances, unwinds her hijab and fluffs her long hair. The upload, since disappeared, registered over 1 million views, and precipitated a spate of responses depicting young women dancing in public places, eventually spawning the hashtag #DancingIsNotACrime. In many cultures across many eras, dancing in public has been a tool for resistance. Those employing movement as resistance often do so precisely because street dance is portable, mutable, and infinitely viral: capable of transmission by person-to-person contact. Multiple subaltern revolutionary movements have begun in search of safe spaces for dancing, and the repression of public dance has been a locus for authoritarian crackdowns. Drawing upon methodologies from semiotics, musicology, kinesics, and political science, this essay explores #DancingIsNotACrime as a potent, present, and immediate vehicle seeking justice and social revolution.
Mi culo es mío: políticas de género y significaciones recientes de las eróticas de baile, del meneaíto al twerking
Authors: Liska Mercedes
Published: December 2023

El baile erótico ejecutado con músicas como la cumbia o el reggaetón ha sido señalado con insistencia en ámbitos educativos e institucionales como una práctica de reproducción de la desigualdad de género y la cultura de la violación. En Argentina, recientemente ganaron aceptación otras miradas impulsadas por artistas mujeres a favor del perreo y sobre todo del twerk, una técnica globalizada de baile pélvico dispuesto en coreografías de participación femenina, con retóricas de reapropiación del goce y la soberanía sexual. Desde el enfoque de la comunicación y la cultura, este trabajo investiga el lugar que ocupó el baile sexualizado en los discursos actuales. Analizamos el rol de distintas cantantes y bailarinas en la revalorización sensual del baile como parte de los imaginarios post románticos y desheteronormativos, su diálogo y discusión con referentes del activismo feminista, y el protagonismo estético y político de una zona del cuerpo: el culo.
Embodying Resistance
Authors: Pasquarello Beauchamp Rose , Davenport Donna
Published: December 2023

The struggle for justice is not new, yet the impact of intentional embodiment and dance in protest is on the rise. Bringing together embodied anti-racist work and dance as a practice of resistance, this artists’ statement describes a grassroots coalition in Rochester, NY: Artists Coalition for Change Together. Co-founded in 2017 as a response to the recent election, ACCT began as an organization of progressive dance artists and collaborators who sought to generate social change through performance, direct action, community dialogues, and scholarship. Written as a dialogue between two founders of ACCT, this statement examines the history of the coalition and its acts of embodied protest. As moving bodies and art communicated resistance in direct “ACCTions,” community activism was generated. Through the lens of existing research and college courses on arts activism, the authors reference multiple reckonings in the North American cultural body, which peaked during the pandemic in 2020.
Izzivi arhiviranja gradiva iz informacijskega sistema za upravljanje z dokumenti (ISUD) v javni upravi z vidika arhivista
Authors: Koncilija Žiga
Published: December 2023

Informacijski sistemi za upravljanje z dokumenti (krajše ISUD) predstavljajo enega izmed ključnih informacijskih sistemov vsake organizacije, saj z njimi upravljajo s svojim dokumentarnim gradivom skozi njihov celoten življenjski cikel, od nastanka do arhiviranja. Pravilnik o pisarniškem poslovanju, ki je stopil v veljavo 1989, prvič omenja vodenje evidenc dokumentarnega gradiva v elektronski obliki, kar ne nazadnje predstavlja osnovo za začetek razvoja in kasnejšega postopnega uvajanja dokumentnih sistemov v javni upravi. Dobrih let 30 let kasneje postajajo zahteve po sistemsko urejenem izročanju tovrstnega arhivskega gradiva pristojnim arhivom, oz. v slovenski elektronski arhiv, postopoma vedno glasnejše. Avtor v prispevku raziskuje okvire postopka arhiviranja gradiva iz ISUD, ob tem pa opozarja na številne izzive, ki nas čakajo pri praktičnem prevzemanju.