bluuebunny/crossref_metadata_2025 huggingface dataset:
Prognostic significance of hepatocyte growth factor in non-metastatic colorectal cancer
Authors: Bogomolova I. A. , Dolgova D. R. , Antoneeva I. I. , Abakumova T. V. , Gening T. P. , Udalov Yu. D.
Published: August 2024

Hepatocyte growth factor (HGF), produced by mesenchymal cells, stimulates mitogenesis and angiogenesis in tumor cells. Tumor cells of some solid tumors do not secrete HGF. The aim of the study was to evaluate the prognostic significance of HGF expression in tumor tissue in colorectal cancer (CRC). The study included 50 patients with stage II-III colorectal cancer; they underwent radical surgical treatment, followed by adjuvant chemotherapy according to the FOLFOX/XELOX regimen. In primary tumor samples, quantitative PCR was used to assess the level of HGF expression. Statistical processing of the obtained data was carried out using STATISTICA 13.0, BioStat v.7.1., and Jamovi 1.6.8 software. The study aims to study a new marker. Comparison of characteristics in the case of non-normal distribution was carried out using the nonparametric Mann–Whitney U test. Cox and Kaplan–Meier linear regression tests were used to analyze progression-free survival. When discussing the results, we used our previously obtained data on the level of expression of TGF-β and CXCL8 in the tumor tissue. As a result of the studies, it was found that in 60% of tumor samples HGF was not expressed, but it was significantly higher than in the resection line samples. Analysis of relapse-free survival in patients with CRC according to the level of HGF expression (predicted level by proportional hazards assessment – 0.7) showed that the median survival in groups 1 (HGF expression more than 0.7) and 2 (HGF expression less than 0.7) was 23.3 and 62.9 months, respectively (long rank test p = 0.215). It was shown that the level of HGF mRNA in CRC tumors does not depend on age, stage of the disease, and sensitivity to FOLFOX/XELOX chemotherapy. The expression level is significantly reduced in tumors with a KRAS mutation and increased in those with a BRAF mutation, in poorly differentiated tumors. Using the level of HGF expression in the tumor tissue of patients with non-metastatic CRC before the start of chemotherapy to assess the prognosis of the relapse-free period is only possible in conjunction with the expression of TGF-β, CXCL8 in the tissue and the level of CEA in the blood of these patients.
Studying the anti-inflammatory activity of Bifidobacterium bifidum supernatants and chicken embryo cells on a model of opisthochic invasion
Authors: Kostolomova E. G. , Lozovaya P. B. , Polyanskih E. D. , Timokhina T. Kh. , Paromova Ya. I.
Published: August 2024

Morphological changes in the liver during infection with Opisthorchis felineus are characterized by significant structural changes. It has been proven that O. felineus modifies immune reactivity by increasing the synthesis of IL-10 and TGF-β and decreasing the levels of IL-4 and IL-5. The experiment was carried out on 15 Mesocricetus auratus aged from 4 to 6 weeks. The animals were divided into 3 equal groups. The duration of observation was 24 days. Live metacercariae of O. felineus were isolated from infected cyprinid fish. Infection was carried out by oral administration of 50 metacercariae. Animals in the experimental groups were injected intraperitoneally with 1 ml of the test supernatants. Histological preparations were examined by video microscopy with morphometry. It has been established that in the acute phase of opisthorchiasis, general infiltration of the portal tract area predominates. The cellular composition of infiltrates is characterized by the presence of lymphocytes, macrophages, fibroblasts, epithelioid cells and foreign body cells. The described cell changes are associated with a local decrease in oxygen access to hepatocytes in the peripheral zone of the lobule due to their compression by fibrous tissue. In the liver of the experimental groups, only tissue-specific changes were noted, and the damage to hepatocytes was the least pronounced in the group with the introduction of B. bifidum supernatant. The cytokine profile in the control group corresponded to the Th1 variant. In experimental group 1, when using the supernatant of B. bifidum, in comparison with the control, the ability of lymphocytes to produce the main pro-inflammatory cytokine, TNFα, decreased 4 times; a suppressive effect was also observed in relation to IL-1β, IL-2, IL-6, IL-8, and IFNγ. Inhibition of IL-10 production was observed, while the level of IL-4 and IL-5 increased in comparison with the control. When using the supernatant of chicken embryo cells, we observed similar results to group 1: a suppressive effect on pro-inflammatory and activation of the production of anti-inflammatory cytokines. IL-17 levels decreased in both experimental groups. Activation of the production of anti-inflammatory cytokines in experimental groups modulates the immune response towards Th2, which helps block inflammatory effects.
Frequency of polymorphism of the C-589T IL4 and G-1082A IL10 genes in children with new coronavirus infection
Authors: Ageeva E. S. , Ablaeva R. N. , Rymarenko N. V. , Yatskov I. A. , Beloglazov V. A. , Zhukova A. A.
Published: August 2024

Immune responses are involved in the initiation and development of COVID-19. Compared with mild COVID-19 cases, serum interleukins levels were significantly increased in severe and critical COVID-19 patients. Increases in IL-4 and IL-10 are associated with disease severity. The C-589T polymorphism of IL4 gene is associated with increased promoter activity of gene. Allelic variants GA and GG-1082 of IL10 gene have greater activity compared to the AA-1082 IL10. The purpose was to study the frequency of occurrence of polymorphic variants of the C-589T IL4 and G-1082A IL10 genes in children with a new coronavirus infection in the population of Crimea. Methods. Examined: 68 patients aged 0 to 14 years with a diagnosis of moderate and severe COVID-19, 100 adult patients (45.6±6.14 years). The frequency of occurrence of polymorphisms of the C-589T IL4 and G-1082A IL10 genes was analyzed. Results. The CC and CT variants of the C-589T IL4 in the group of children were more common than the TT C-589T IL4 variants. Statistically significant differences in the frequency of occurrence of the mutant CC genotype of the C-589T IL4 were shown between groups of children and adults. Statistical analysis did not reveal any genotype differences with disease in either children or adults. Analysis of the prevalence of G-1082A IL10 genotypes showed that in children the most common is GA. The same trend is typical for adults and control group. Conclusions. Analysis of the odds ratio showed that there was no pathogenetic significance between the polymorphism of the C-589T IL4 and G-1082A IL10 genes and the risk of developing a new coronavirus infection in the studied groups.
On the issue of experimental modeling of invasions and prospects for the use of immunostimulants in nematodes
Authors: Zhdanova O. B. , Andreianov O. N. , Martusevich A. K. , Chasovskich O. V.
Published: August 2024

Currently, the search for ways to overcome drug resistance to anthelmintics is relevant. This problem is solved by limiting the duration of use of drugs with the same mechanism of action and combination of anthelmintics. The studies presented in the article have shown that the use of immunotropic drugs is also very promising.
Forty white mice and 20 white rats were used for experimental modeling of Trichinella spiralis and Trichinella nativa invasions. Changes in lymphoid tissue associated in the intestine, in the spleen, as well as in the peripheral blood of animals and birds during inoculation of the above species were studied. Further, the effect of drugs with immunotropic activity was studied on proven models of Trichinella spiralis invasions, for which 30 white mice (20.5±2.5 g) were used, which were randomized and divided into groups. The evaluation of the protective properties of immunotropic drugs in trichinosis was carried out on laboratory models to determine the survival rate in studies after euthanasia of all mice and counting the number of Trichinella larvae. Both experiments were conducted in accordance with the principles of the Helsinki Declaration. After removing laboratory animals from the experiment (in accordance with the principles of the above declaration), macro- and microanatomic studies and sampling of histological material (sets of intestines and spleens) were carried out for qualitative and quantitative assessment.
The above is confirmed by the fact that parasitological studies have established the high effectiveness of polyoxidonium in relation to the survival of Trichinella larvae, which was accompanied by an increase in the area of lymphoid tissue associated with the intestine and the white pulp of the spleen, in which lymphoid follicles grew. Thus, polyoxidonium is an effective drug that can be used in the complex treatment of nematodes as an immunotropic agent.
Exploration of Data Mining Techniques in Business Decision-Making
Authors: Gustiana Zelvi
Published: August 2024

This research examines the use of data mining techniques in business decision-making. By analyzing various data mining methods such as classification, clustering, and association, the study demonstrates how data mining can enhance operational efficiency and marketing strategies. The literature review provides insights into the practical applications and benefits of data mining across different industries. The research highlights the potential of data mining to uncover hidden patterns and trends in large datasets, which can be used to make more informed and timely business decisions. Additionally, the study identifies key challenges in implementing data mining, such as data integration, selecting appropriate algorithms, and interpreting results. The findings are expected to offer practical guidance for companies aiming to leverage data mining in their operations. By understanding the advantages and applications of data mining, businesses can improve their decision-making processes, optimize resource allocation, and develop more effective strategies. This research serves as a valuable resource for organizations looking to harness the power of data mining to gain a competitive edge in the market.
EL PRESUPUESTO DE LA UNIÓN EUROPEA: ORÍGEN, EVOLUCIÓN Y PERSPECTIVAS
Authors: GIMÉNEZ DÍAZ-OYUELOS MARÍA LUISA
Published: August 2024

La presente obra nos presenta un fuerte trabajo de investigación centrado en el estudio económico-financiero de una organización supranacional en fase de crecimiento y desarrollo: la Unión Europea.
LA TELEVISIÓN PÚBLICA EN LA TRANSFORMACIÓN DEL ESTADO DE BIENESTAR
Authors: MANFREDI SÁNCHEZ JUAN LUIS
Published: August 2024

Trabajo de investigación sobre la influencia de la televisión pública en el Estado de Bienestar, centrándose en la televisión pública estatal española: financiación, organización y control.
Pendampingan Sistem Informasi Desa Berbasis Internet di Desa Laikaaha Kecamatan Ranomeeto Konawe Selatan
Authors: Lestari Lina , Variani Viska Inda , Rusman La Ode , Raharjo Sapto , Midana Ashari
Published: August 2024

Laikaaha Village, Ranomeeto District, is one of the villages in South Konawe, Southeast Sulawesi which has diversity in social life. This diversity consists of economic capacity, education, resilience and health which provides its own challenges for the Village Government to develop village development programs. Determining village policies or preparing village programs is very dependent on accurate data, so managing village data and information is very important. Apart from that, the use of an internet-based information system is one of the facilities that can help the Village Government in implementing village programs. Currently, data traffic always moves fast, so assistance is provided with the management of internet-based information systems to produce reliable human resources to manage it.  The output of this activity is to increase the capacity of village information system managers so that information system utilization can be maximized. In this activity, the community as users is also involved, and assistance has been provided on how to utilize the existence of the information system. The aim of this community service activity plan is that the Laikaaha Village community has knowledge about the use of information systems, information system managers can improve their skills, the Village Government can make policies and develop programs that are more precise and faster.
PENGENDALIAN RIJEK PRODUK JUS KEMASAN 5 LITER MENGGUNAKAN METODE SEVEN TOOLS DI PT. AMANAH PRIMA INDONESIA
Authors: Sahroji Sahroji , Sahputra Rahmat , Rohimah Anni
Published: August 2024

PT. Amanah Prima Indonesia adalah perusahaan yang memproduksi minuman sari buah dengan berbagai jenis kemasan, diantaranya adalah jeriken plastik 5 liter, botol plastik 1 liter, botol plastik 250 ml dan botol kaca 250 ml, ditemukan produk cacat atau rijek pada kemasan jeriken plastik 5 liter dikarenakan seal yang tidak rapat sehingga udara masuk kedalam kemasan dan mengakibatkan bakteri tumbuh, Terjadinya kecacatan ini diakibatkan dari berbagai faktor yaitu manusia, mesin, metode dan material hal yang dapat dilakukan untuk menghilangkan atau mengurangi riject pada produk yaitu melakukan suatu penelitian dengan menggunakan seven tools. metode seven tools dilakukan untuk mengetahui faktor-faktor penyebab dan diperoleh 4 aspek faktor usulan perbaikan dari hasil diagram sebab akibat yaitu dengan cara memperhatikan aspek manusia, mesin, metode, dan material.
The effects of exogenous additives on the vitality of Chinese pearl oyster (Pinctada fucata) sperm under different conditions
Authors: Li Minghao , Fu Zhengyi , Yang Rui , Yu Gang , Zhou Wenli , Ma Zhenhua
Published: August 2024

During the artificial breeding process of Chinese pearl oysters, the quality and vitality of sperm and eggs are pivotal in determining the success rate of fertilization. This study delves into the impact of externally added fructose, glucose, and ammoniated water on sperm vitality and lifespan under varying temperature conditions. The results indicate that the addition of exogenous energy sources and cell protectants, specifically monosaccharide energy substances, significantly improves sperm vitality. Moreover, under 4°C conditions, adding 2.8 mmol/L fructose, glucose, and 2 mmol/L ammoniated water to sperm samples significantly enhances sperm vitality and prolongs their lifespan. This provides strong evidence for the feasibility of short-term preservation and vitality enhancement strategies for Chinese pearl oyster sperm and also offers important scientific support for optimizing the artificial reproduction techniques of Chinese pearl oysters.
Achieving Governmental Innovation through Artificial Intelligence Adoption
Authors: Ayed  AlGarni Dr. Abdullah , M. Malkawi Professor Dr. Nazem , N. Malkawi Engineer Mahdi
Published: August 2024

The study aimed to identify the role of readiness for artificial intelligence (AI) requirements (technical infrastructure, data sets, administrative and organizational readiness, laws and legislations, AI ethics, and societal challenges) in government innovation from the point of view of the employees in Jordanian government agencies. (342) valid questionnaires were collected from employees working at information technology departments of Jordanian government agencies. After analyzing the data, the study concluded that the level of availability of artificial intelligence in Jordanian government agencies is moderate, and the degree of availability of the sub-dimensions of artificial intelligence was moderate, except for two dimensions data sets and legislation, which came within high level. The availability of government innovation is high. The study also found there is a significant effect of artificial intelligence on government innovation in Jordanian government agencies and explained 62% of the variance in government innovation. The study recommended the need to pay attention to the development of artificial intelligence requirements because of continuous development in technology and environment, and to make this a continuous process. In addition, government agencies need to cooperate with public and private sector organizations, build partnerships with them for the benefit of both in developing artificial intelligence, and thus government innovation, and making artificial intelligence and government innovation on the ladder of their priorities and strategic plans.
Assessment of Drainage System in Bangetayu Kulon Village, Genuk District, Semarang City
Authors: Nugraha Winardi Dwi , Shinta Triya , Sarminingsih Anik , Istirokhatun Titik
Published: August 2024

The drainage system is infrastructure related to urban spatial planning and must be considered. This planning was carried out in Bangetayu Kulon Village, Genuk District, Semarang City, which consists of residential, commercial and other areas. Bangetayu Kulon sub-district has inundation problems at several points due to a lack of channel capacity caused by high sedimentation at the bottom of the channel, vegetation, rubbish and changes in land use. In evaluating the drainage system, a 5 year return period hydrological analysis will be carried out using EPA SWMM 5.1 software. Apart from that, a hydraulic analysis will also be carried out which begins with an analysis of existing conditions, then applies SUDS and continues with evaluation through channel normalization in the form of sediment burrowing and changes in channel dimensions. The concept of implementing SUDS in the Bangetayu Kulon Village drainage system is the application of Permeable Pavement on road areas that do not yet have paving pavement of 30,877 m2 and a Retention Pool with a storage capacity of 10,560 m3. This plan succeeded in reducing flooding by 52.06% from initially 147.82 x 106 L to 70.84 x 106 L.
From Glaciers to Grasslands: Comparative Analysis of Climate Trends in Manang and Mustang, Nepal
Authors: Ankita Pokhrel , Fang Ping
Published: August 2024

This study examines the effects of climate change on Nepal's Manang and Mustang districts by analyzing temperature and precipitation trends, changes in glacial extent, and land cover transformations. Utilizing Landsat imagery from 1992 to 2023 and historical meteorological data, we assess environmental changes in land cover. The results indicate significant decreases in precipitation, particularly during the monsoon season, alongside increases in grassland cover and reductions in barren and forested areas. Manang shows a distinct pattern with rising snowfall, whereas Mustang experiences a notable decline in rainfall, underscoring the necessity for regionspecific adaptation strategies. These findings offer critical insights for shaping climate policies and developing robust strategies to enhance the resilience of high-altitude environments.
Pelatihan Pembuatan Sabun Ramah Lingkungan Dari Buah Lerak Sebagai Implementasi Model Pemberdayaan Ibu Rumah Tangga
Authors: Rejeki Desi , Nur Halimah  , Dewi Puspa Arisandi  , Moh Syahrul Munir
Published: August 2024

Limbah detergen merupakan persoalan lingkungan harus diprioritaskan. Limbah detergen memiliki dampak besar dalam mencemari lingkungan dan merusak ekosistem.  Di limbah detergen terkandung surfaktan yang dapat mencemari air dan biota yang ada. Limbah busa yang dihasilkan deterjen disinyalir mengakibatkan mikroorganisme didalam air kekurangan asupan oksigen. Selain itu kemasan pada detergen rata-rata berbahan plastik sehingga menyumbang pencemaran lingkungan.  Ibu rumah tangga merupakan bagian dari masyarakat yang menghasilkan limbah deterjen setiap harinya. Sehingga peran ibu rumah tangga menjadi sangat penting untuk meminimalisir pencemaran limbah deterjen kimia. Pengabdian ini dinyatakan berhasil ditinjau dari aspek afektif dan kognitif, peserta pelatihan telah memahami cara membuat sabun alami dari buah lerak dan memahami bahaya pencemaran limbah deterjen kimia. Oleh karena itu untuk mengetahui tingkat keberhasilan kegiatan ini maka metode yang digunakan adalah dengan memberikan kuesioner yang dibagikan sebelum dan setelah pemaparan materi yang berisi pertanyaan-pertanyaan yang berkaitan dengan materi pelatihan. Berdasarkan hasil kegiatan pengabdian yang telah dilakukan disimpulkan bahwa pemaparan materi yang disampaikan , diterima dengan baik dan mampu menarik minat peserta untuk terlibat aktif dalam diskusi. Sehingga didapatkan peningkatan pengetahuan peserta tentang pelatihan pembuatan sabun ramah lingkungan dari buah lerak untuk mendukung peningkatan kualitas lingkungan yang diketahui dari perbandingan hasil kuesioner sebelum dan setelah penerimaan materi.
Diversity and Inclusion Programs to Promote a Diverse Workforce and Create an Inclusive Environment in China: Lessons from Case Study of Google and Alibaba
Authors:   Faculty of Economics and Management Universiti Kembangan Malaysia, Xuan Wang , Selvaratnam Doris Padmini ,   Faculty of Economics and Management Universiti Kembangan Malaysia
Published: August 2024

Corporate businesses are paying more and more attention to the value of diversity and inclusion (D&I) in the context of faster globalization. In addition to bringing fresh viewpoints and creative ideas, a diverse workforce helps corporate organizations become more competitive and adapt to changing market conditions. This article uses case studies on Alibaba and Google to illustrate its goal of encouraging diversity in the workforce and building inclusive environments in China. Promoting diversity and inclusivity presents special opportunities as well as problems for China. In addition to being crucial components of corporate social responsibility, diversity and inclusion are also necessary for businesses to thrive sustainably. According to this survey, global businesses with a diverse workforce outperform others in terms of employee performance and innovation. But for many Chinese and international businesses, the question of how to successfully advance diversity and inclusion initiatives within the framework of Chinese corporate culture continues to be a major concern. In order to effectively support Chinese companies in promoting diversity and inclusion programs, this paper carefully selects two representative companies, Alibaba and Google, as case studies. The goal is to analyze the diversity and inclusion practices of these two global tech giants and examine their successes and shortcomings. Alibaba, one of the top Chinese corporations, is likewise well-known for its diversity and inclusion initiatives, and Google, a major player in the computer industry, is widely praised for its initiatives in this area.This paper's study goals include summarizing the experiences and flaws of Google and Alibaba, as well as analyzing and assessing the efficacy of their unique diversity and inclusion initiatives. to suggest inclusion and diversity initiatives that are appropriate for Chinese businesses. Data analysis, case studies, and literature reviews make up the bulk of the research process.
The Role of Trust and its Influencing Factors in the Hospital Industry Indonesia Case
Authors:   Esa Unggul University, Jakarta, Indonesia, Vidya Putri Kartika , Hasyim Hasyim ,   Esa Unggul University, Jakarta, Indonesia, Hosizah Hosizah ,   Esa Unggul University, Jakarta, Indonesia
Published: August 2024

Trust is important for a hospital, because trust is a variable that can bridge various independent variables to the dependent variable. Trust that is embedded in the minds of patients will be a factor that patients consider in choosing a hospital, high trust will provide benefits for the development of the hospital. This study aims to analyze the role of trust level on patient revisit intention. The research method uses quantitative causal research to see the relationship between one variable and another. Hypothesis proving uses a structural equation model that shows whether or not there is an effect of changes in the independent variable on changes in the dependent variable. The study used 155 sample respondents who were hospital patients during the period 2021 to 2023, who were taken by purposive sampling by setting criteria such as having undergone outpatient care. The research results show that in structure one, the level of trust is not influenced by the use of E Wom, but the level of trust is influenced by the value perceived by the patient. Sleian that e- wom also does not affect changes in patient revisit intentions. However, customer perceived value still has an influence on revisit intentions. The findings show that the level of trust does not mediate the relationship between e-wom and revisit intentions but the level of trust acts as a mediator of the relationship between customer perceived value and revisit intentions. This conclusion can be interpreted that E-wom is not a factor considered by patients to make a repeat visit to the destination hospital. Factors that are considered by patients to make a re-visit to the hospital if the hospital can provide the value expected by patients in visiting the hospital. The expected value is, time value such as the speed of service delivery, service value that meets patient expectations. monetary value that can be perceived is perceived according to the patient's sacrifice at the cost incurred. The value provided by the hospital will encourage high hospital trust which will ultimately increase repeat visit intentions.
Exploring the Playwright’s Self-Representation in Tom Stoppard’s Dramatic Works
Authors:   UH2C, FLSHM, Morocco, MAJDOUBI Dr. Ilham EL
Published: August 2024

This article examines two masterpieces by the British playwright and screenwriter Tom Stoppard: the two-act play The Real Thing and the screenplay Shakespeare in Love. These works employ the author-as-character technique in disparate ways. This study will endeavor to demonstrate how the playwright interweaves artistic and realist elements, as well as the ways in which his intricate techniques of synthesis impact the written page and the theatrical stage.
Wisata Syariah dan Strategi Pengembangannya di Era Digital Pada Beberapa Tempat Wisata di Sumatera Barat
Authors: Ezizwita Ezizwita , Srihasnita Rita , Maivalinda Maivalinda , Firsta Firsta , Oktovia Nettry , Agustin Fenny
Published: August 2024

Tourism is one of the government's main sectors to increase revenue. In 2016, West Sumatra was designated as a Global Halal Tourism Destination in Abu Dhabi, which is expected to provide an impetus for West Sumatra's government to introduce Sharia tourism in their area. The concept of Sharia tourism is to apply Islamic values to all aspects of tourism activities. This is very suitable to be implemented in West Sumatra Province where the majority of the population is Muslim. This research aims to identify the appropriate development strategies that can be applied by adopting the concept of Shariah tourism and using digital marketing for several tourist attractions in West Sumatra. By using a SWOT analysis, the opportunities and challenges faced by the Sharia tourism sector can be identified. As a result, a strategy can be practically applied by the Sharia tourism business in facing the digital era. This research is expected to raise awareness about the importance of digitalization skills in product marketing. The research method is descriptive qualitative. Through the SWOT analysis, it is possible to identify the various SWOTs and to formulate the digital marketing based strategy for the development of Islamic tourism in West Sumatra
 
Abstrak
Sektor pariwisata merupakan salah satu sektor andalan bagi pemerintah untuk menambah pendapatan. Ditetapkannya Sumatera Barat sebagai daerah tujuan pariwisata halal dunia dalamWorld Halal Tourism di Abu Dhabi tahun 2016, selayaknya dijadikan momentum oleh Pemerintah Provinsi Sumatera Barat untuk menerapkan pariwisata berbasis syariah di wilayahnya. Konsep wisata syariah adalah menerapkan nilai-nilai ke Islaman ke dalam seluruh aspek kegiatan wisata. Hal ini sangat sesuai untuk diterapkan di Provinsi Sumatera Barat yang penduduknya mayoritas beragama Islam. Penelitian in bertujuan untuk melihat strategi pengembangan apa yang cocok diterapkan yang mengusung konsep wisata syariah dengan memanfaatkan Digital Marketing pada beberapa objek wisata yang ada di Sumatera Barat. Melalui SWOT dapat diketahui peluang dan tantangan yang dihadapi oleh dunia wisata syariah sehingga diperoleh suatu strategi yang bisa diterapkan oleh bisnis wisata syariah. Penelitian ini diharapkan dapat meningkatkan kesadaran akan pentingnya kemampuan digitalisasi dalam pemasaran produk. Metode penelitian yang digunakan adalah kualitatif deskriptif. Dengan analisa SWOT, dapat diketahui berbagai kekuatan, kelemahan, peluang dan ancaman yang dimiliki dan dihadapi oleh wisata syariah di Sumatera Barat, sehingga akan diperoleh suatu strategi pengembangan wisata syariah berbasis Digital Marketing yang bisa diterapkan di Sumatera Barat.
MISSÕES DE MANUTENÇÃO DA PAZ E OS SEUS REFLEXOS SOCIOECONÔMICOS
Authors: Do Couto Pereira Raphael , Mello de Lima Fernanda , Aguilera Negrete Ana Carolina
Published: August 2024

Este trabalho tem como objetivo apresentar as ações da Missão das Nações Unidas para a Estabilização do Haiti e seus reflexos na economia daquele país. Serão descritas as operações de paz, o histórico e evolução político econômica do Haiti, os reflexos das crises políticas na economia haitiana, a crise haitiana e intervenção das Nações Unidas, ainstauração da Missão das Nações Unidas para Estabilização do Haiti (MINUSTAH), o Governo Transitório, o Interim Cooperation Framework (ICF), a MINUSTAH e estruturação sócio-político e econômica do Haiti, o furacão Jeanne e o apoio da MINUSTAH e da ICF ao país, a economia haitiana pós-crise,  a evolução econômica do Haiti e o terremoto e suas conseqüências econômicas. Essa descrição tem como fontes os documentos gerados pela Comissão Econômica Para a América Latina e o Caribe (CEPAL). São eles: Haiti: Évolution Économique De L’année 1999;  Haití: Evolución Económica Durante 2004 y Perspectivas para 2005; Haití: Evolución Económica Durante 2005 y Perspectivas para 2006; Haití: Evolución Económica Durante 2007 y Perspectivas para 2008 e Haití Evolución Económica durante 2010, utilizados na demonstração da evolução econômica haitiana, a fim de aferir os impactos causados na economia do país até o pós terremoto em 2010. A metodologia empregada será documental e bibliográfica: documental porque serão utilizados textos legais, atos normativos de âmbito Internacional e bibliográfica, pois que serão pesquisados doutrinas e textos acadêmicos de assuntos relacionados ao tema.
A brief overview of collective consumer redress in the European Union and South Africa and moving towards the increased use of consumer class action in South Africa (part 1)
Authors: Broodryk T
Published: August 2024

Hierdie tweedelige artikel bied ’n oorsig oor kollektiewe verbruikersregstelling in die Europese Unie en in Suid-Afrika. Dit bekyk redes waarom in die Suid-Afrikaanse reg die bestaande klasaksie onderbenut bly as ’n meganisme om verbruikersgeskille mee op te los. In die afgelope sowat 30 jaar, is slegs twee sertifiseringsuitsprake in verbruikersklasaksies gelewer wat oor ’n geskil handel wat beheers word deur artikel 4(1) van die Wet op Verbruikersbeskerming. Die onlangs uitgereikte aanwysing oor kollektiewe regstelling om die kollektiewe belange van verbruikers te beskerm van die Europese Unie, is aanduidend dat dit vir die Europese Unie ’n prioriteit is om verbruikersbelange te beskerm en dat ’n omvattende benadering verkieslik is om kollektiewe verbruikersregstelling in lidlande te hanteer. Die gebrek aan wetgewende regulering van die Suid-Afrikaanse klasaksie soos ook van die meganisme vir verbruikersklasaksie wat in die Wet op Verbruikersbeskerming vervat is, bring mee dat die klasaksie sedert die instelling daarvan meer as ’n dekade gelede, steeds onderbenut bly. Ander faktore wat tot die onderbenutting van die verbruikersklasaksie bydra, is onder meer die onduidelike formulering van die Wet op Verbruikersbeskerming, verbruikers se gebrek aan kennis ten aansien van hul regte ingevolge die Wet op Verbruikersbeskerming en die afwesigheid van voldoende hulpbronne om verbruikers in staat te stel om hulle regte af te dwing, onder meer deur middel van so ’n klasaksie. Op hulle beurt belemmer al hierdie faktore toegang tot geregtigheid, wat juis die primêre doel van Suid-Afrika se klasaksie is. Deel een van hierdie tweedelige artikel handel oor die ontwikkeling van kollektiewe regstelling in die Europese Unie asook die besonderhede van die aanwysing betreffende kollektiewe regstelling van die Europese Unie. In deel twee oorweeg die outeur kollektiewe regstelling in Suid-Afrika. Daarin ondersoek die outeur verder die redes waarom Suid-Afrika se klasaksie onderbenut bly as ’n meganisme om verbruikersgeskille op te los. Die bespreking bevat ook voorstelle, onder andere gebaseer op die Europese ervaring, vir die toenemende benutting van die Suid-Afrikaanse verbruikersklasaksie. Dit behels, onder andere, die regulering van die meganisme deur wetgewing asook die bemagtiging van Suid-Afrikaners om hul sodoende in staat te stel om hul regte, soos vervat in die Wet op Verbruikersbeskerming, uit te oefen. Die oogmerk van die outeur met die artikel is om ’n bydrae te lewer tot die toenemende benutting van die Suid-Afrikaanse verbruikersklasaksie om sodoende toegang tot geregtigheid vir Suid-Afrikaanse verbruikers te help bewerkstellig.
Memaksimalkan Peran Dana Wakaf untuk Pengembangan Industri Halal
Authors: INDAH MAESAROH  , Nuryitmawan Tegar Rismanuar
Published: August 2024

Penelitian ini bertujuan untuk mengusulkan kerangka bisnis yang bertujuan untuk memaksimalkan peran dana wakaf terhadap ekosistem halal di Indonesia. Peneliti bermaksud untuk mengevaluasi fleksibilitas dana wakaf karena berbiaya rendah sebagai source of fund yang dapat memicu pertumbuhan bisnis UMK. Pendekatan kualitatif digunakan, terutama pendekatan studi pustaka (library research) dari berbagai sumber data penelitian sebelumnya. Hasilnya menunjukkan bahwa lembaga pengelola wakaf uang bisa melakukan pemberdayaan dengan memberikan bantuan berupa modal investasi ataupun modal untuk keberlanjutan usaha agar pengelolaan dana wakaf menjadi lebih produktif. Studi ini menemukan dua pendekatan dalam proses bisnis penyaluran dana wakaf kepada Lembaga keuangan mikro syariah yaitu top-down dan bottom up yang memiliki tujuan pada peningkatan performa bisnis dan skala bisnis. Syarat pembiyaan yang dilakukan khususnya untuk UMK yang telah mempunyai setifikasi halal, maka harapannya bisa memajukan industri halal Indonesia dan meningkatkan nilai ekspor dengan jangkauan yang lebih luas
Kata Kunci: Dana Wakaf, Industri Halal, LKMS
Prevalence of Cryptosporidium Infection among Children Attending Maryam Abacha Women and Children Hospital, Sokoto State, Nigeria
Authors: Bunza Nura Muhammad , Unata Iduh Michael , Isiaka M , Yusuf Suleiman
Published: August 2024

Study's Excerpt/Novelty

This study investigates the prevalence of Cryptosporidium among children attending Maryam Abacha Women and Children Hospital, Sokoto, using Formol ether concentration and Modified Ziehl Neelsen staining methods.
It identifies a high prevalence of (71.1%) and shows a strong correlation between Cryptosporidium infection, diarrhea, and source of drinking water.
These findings underscore the necessity for routine diagnostic testing of Cryptosporidium among children for improved detection, treatment, and overall patient outcomes in the region.

Full Abstract
Cryptosporidium infection is ranked as the second most common cause of diarrheal disease and fatalities among children in developing nations.  Nonetheless, due to the fact that many healthcare providers do not consistently request Cryptosporidium diagnostic tests, the prevalence of cryptosporidiosis is probably underestimated.  The current study is therefore aimed at investigating the prevalence of cryptosporidiosis among children attending Maryam Abacha Women and Children Hospital (MAWCH), Sokoto.  During the timeframe of April to June 2021, stool samples were collected from 114 diarrheic and non-diarrheic children and analyzed using Formol ether concentration and Modified Ziehl Neelsen staining methods.  Out of 114 samples analyzed, 81(71.1%) were positive for Cryptosporidium oocysts.  A higher prevalence of Cryptosporidiosis was observed in males 45(39.5%) compared to females 36(31.6%) participants and higher 41(36.0%) in younger children aged 0-1 years than the older children.  Similarly, a greater prevalence of Cryptosporidiosis was observed in diarrheic children (42.1%) than in non-diarrheic children (28.9%).  A statistically significant relationship was observed between the occurrence of Cryptosporidium and diarrhea (P = 0.002) and the source of drinking water (P = 0.001).  Routine diagnosis of Cryptosporidiosis among children is vital and can enhance effective diagnosis, treatment, and consequently, improvement in the patients' well-being.
Heavy Metal Contamination Risks in Environmental and Vegetable Samples around a Metal Workshop in Kofar Marusa, Katsina Metropolis
Authors: Kabir, H. G.  , Yar’adua, A.  I.  , Matazu, K.  I.  , Lawal, R.  G.  , Kabir, Z.  G.  , Bala, M.  G.  , Mukhtar, M. U.  , Sani, A. S.  , Bashir, A.  , Matazu, H. K.
Published: August 2024

Study’s Novelty/Excerpt

This study focuses on the health risks associated with heavy metal contamination in vegetables irrigated near a metal workshop in Kofar Marusa, Katsina Metropolis.
By quantifying the concentrations of various heavy metals in commonly consumed vegetables, the research shows significant variations in metal uptake among different vegetable types, with cress and spinach posing the highest health risks.
The study uses Health Risk Index (HRI) and Target Hazard Quotient (THQ) calculations to show the potential health hazards, particularly for children, highlighting the need for targeted interventions to mitigate these risks in affected communities.

Full Abstract
Heavy metal contamination from Metal workshop activities poses health risks by accumulating in crops and entering the food chain.  This study quantified heavy metal concentrations and health risks in commonly consumed vegetables irrigated near a metal workshop in Kofar Marusa, Katsina Metropolis.  Samples from the cultivation areas of Cabbage, lettuce, tomatoes, spinach, and cress were analyzed.  After acid digestion, the amounts of heavy metals were measured by Atomic Absorption Spectrometry.  Copper (0.123 mg/kg), manganese (0.431 mg/kg), and nickel (0.539 mg/kg) were greatest in spinach.  Manganese (0.374 mg/kg) and cobalt (1.474 mg/kg) levels were higher in cress.  Lettuce had the highest iron concentration (6.028 mg/kg) and the lowest metal levels.  Lead (11.68 mg/kg) and chromium (2.276 mg/kg) were both high in Cabbage, and nickel (0.526 mg/kg) and lead (4.24 mg/kg) were noteworthy in tomatoes.  Among the Health Risk Index (HRI) calculated, cress reached 17.967 for adults.  Children's exposure to heavy metals for Cobalt (Co) and Lead (Pb) through cabbage consumption showed the Target Hazard Quotient (THQ) values for Co (0.089) and Pb (0.036), significantly higher than those for adults.  The Cumulative Lifetime Cancer Risks showed that Cress posed the highest risk for both adults and children, followed by spinach.  The study revealed significant variations in heavy metal concentrations taken up among different types of vegetables, portraying potential health risks associated with its consumption.  It also suggested that the consumption of vegetables cultivated through irrigation near the metal artisanal site may contribute to the bioaccumulation of heavy metals burden among the population.  The study brought to light the wide range of heavy metal uptake in vegetables as well as the possible health hazards associated with eating produce grown close to the metal workshop.
Découverte de Linepithema humile (Mayr, 1868) sur l’île de la Réunion (France) et nouvelle mention pour l’espèce Cyphomyrmex minutus Mayr, 1862 avec inclusion géoréférencée des espèces rencontrées (Hymenoptera : Formicidae : Myrmicinae)
Authors: Colindre Laurent
Published: August 2024

We report for the first time the presence of the Argentine ant Linepithema humile (Mayr, 1868) on Reunion Island and specify the conditions under which we detected it. We also mention the second observation for the ant Cyphomyrmex minutus Mayr, 1862.
A PRODUÇÃO DO ESPAÇO URBANO DA GRANDE CRUZEIRO E SUA RELAÇÃO COM A CIDADE DE PORTO ALEGRE/RS
Authors: Barbosa Ana Patrícia
Published: August 2024

O presente artigo propõe-se a refletir sobre a cidade de Porto Alegre, com acuidade, a partir dos  rastros que escoaram/escoam em seus territórios desde sua fundação, tendo como eixo central analítico a região da Grande Cruzeiro, considerando-a emblemática para apresentar as formas do viver urbano da população das camadas mais pobres, em especial, no que se refere aos novos arranjos territoriais das grandes metrópoles brasileiras, dado o contexto de transformações socioespaciais, reconfigurando espaços e grupos sociais. A análise aqui presente visa a refletir sobre os territórios como espaços vivos tecidos nas relações sociais que a região da Grande Cruzeiro foi construída, evidenciando os interesses em disputa consolidados ao longo do processo de desenvolvimento histórico da cidade de Porto Alegre. Essa questão é analisada neste estudo, a partir de continuidades e rupturas na produção de territorialidades e dinâmicas socioespaciais, por intermédio de uma cartografia espaço-temporal de experiências urbanas, compreendendo a formação do território da Grande Cruzeiro e sua relação com a cidade de Porto Alegre.
Nietzsche na imprensa brasileira do século XIX
Authors: Rubira Luis
Published: August 2024

Dentre os primeiros artigos sobre Nietzsche publicados na imprensa brasileira – conhecidos até o presente momento – estão “O neo-cinismo” (Gazeta de Notícias, RJ, 20/05/1893) e “A filosofia na moda: Frederic Nietzsche” (Jornal do Comércio, RJ, 04/09/1896), o primeiro assinado por “Julio Erasmo” e o segundo pelo “Dr. Ernst”. O presente ensaio visa inicialmente mostrar, por meio de uma investigação do conteúdo de tais artigos, as fontes que serviram de base para a elaboração dos mesmos, para, em seguida, explorar hipóteses acerca da identidade dos autores que realizaram uma interpretação do pensamento do filósofo no período em que ainda vivia na Alemanha.
Dampak Remote Work Pasca COVID-19 terhadap Well-Being Karyawan
Authors: Dara Delila  , Cholicul Hadi
Published: August 2024

This study investigates the impact of remote work on employee well-being in the post-COVID-19 era. Through a literature review, the research highlights that remote work often leads to negative outcomes such as blurred boundaries between work and personal life, increased social isolation, heightened stress, challenges in work-life balance, and declines in performance and productivity. The findings suggest that organizations need to adopt effective strategies to manage these issues, including improving boundary management, enhancing social connectivity, and supporting employees' work-life balance to mitigate the adverse effects of remote work.
Pengaruh Pertumbuhan Perusahaan, Ukuran Perusahaan, Struktur Modal, dan Return on Equity Terhadap Kebijakan Dividen
Authors: Rosalita Dino , Suyatmin
Published: August 2024

This study aims to analyze the impact of company growth, company size, capital structure, and return on equity on dividend policy. The population used in this study consists of manufacturing companies listed on the Indonesia Stock Exchange (IDX) during the period 2020-2022. The sampling technique employed is purposive sampling. The total sample size is 178 for the period 2020-2022. Outliers were removed from the sample, leaving 124 usable observations. The analysis was conducted using multiple linear regression with SPSS version 25. The results show that company growth has a significant impact on dividend policy, while company size, capital structure, and return on equity do not have a significant effect on dividend policy for manufacturing companies listed on the Indonesia Stock Exchange during the period 2020-2022.
Measuring the Competitive Advantage, Market Orientation, and Entrepreneurial Orientation of Local Wisdom-Based SMEs
Authors: Suryono Imam , Astuti Widji , Respati Harianto
Published: August 2024

This research measuringthe market orientation, entrepreneurial orientation, and competitive advantage in local wisdom-based food SMEs in Bogor Regency. This research was conducted locally in Bogor Regency, namely wisdom-based food SMEs because the regional government has promoted programs with local wisdom values that are competitive and sustainable. No empirical or theoretical studies still discuss local wisdom-based food SMEs in the Bogor district. The population in this study were local wisdom-based food SMEs in Bogor Regency, totaling 223 SMEs. The sampling technique uses simple random sampling so that the number is known as many as 143 SMEs. Data was collected using a written survey method and submitted directly or indirectly to respondents to obtain accurate information regarding market orientation, entrepreneurial orientation, and competitive advantage. The research results show that customer orientation is the most significant factor in forming market orientation for SMEs. Entrepreneurial orientation is reflected in a proactive, risk-taking and competitive attitude, with respondents' highest appreciation for a proactive attitude. Competitive advantage can be seen in supporting factors, company strategy, and competition. Respondents' appreciation of supporting factors was highest, reflected in the completeness of the facilities. It is hoped that the contribution of this research will provide information, especially about local wisdom-based food SMEs in Bogor Regency, and provide complete data related to policies to empower and prepare SMEs to have a sustainable competitive advantage.
A Study of theRole of Folk Songs in Preserving the Culture and Heritage: A Case Studyof Bodos
Authors: Boro Dr. Simani
Published: August 2024

The folk song is an important element which is preserved the cultural heritage of the community that receipt from the ancestorsand transformed itfrom one generation to another. It is the cultural sourceofthe community standing onwhicha society can give theiridentity.Thefolk song playsan important role in narrating past social picturesand unwritten history of the societythat are unknown by the people of present generation.In northeast India, the Bodos have their own distinct culturewhich gives their identity.The cultural elements of the community havebeen preserved in folk songs since immemorial period andreflected while these are sung in festivals and ceremonies. We know that through lyrical storytelling and symbolic imagery, folk songs offer insights into the customs, rituals, and folklore of the community, fostering a deeper appreciation for cultural diversity andintergenerational continuity. In thispaper,anattempt has been made to study how folk songs playarolein repositioning cultureandheritage, preservationof linguistic traditions, indigenous knowledges, and ancestral wisdoms.
Implementación de códigos QR para optimizar el proceso de evaluación de los aprendizajes
Authors: Francisco Vásquez Edwis
Published: August 2024

La integración de códigos QR a diversos ámbitos de la cotidianidad es cada día más frecuente, su versatilidad permite implementarlos al ámbito educativo como una herramienta novedosa, brindando beneficios tanto a docentes como a estudiantes.
El objetivo de este estudio es analizar cómo la implementación de códigos QR mejora la calidad de la evaluación de los estudiantes en los politécnicos de San Felipe de Puerto Plata durante el año escolar 2023-2024. Para lograrlo, se empleó una metodología que combina enfoques cuantitativos y cualitativos, evaluando los efectos de la implementación de los códigos QR en la educación. La población objeto de investigación está conformada por docentes y estudiantes de los politécnicos mencionados.