bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the maturity of the current global system for combating financial and
cyber fraud
Authors:   Sumy State University,
            Ukraine, Kuzmenko Olha , Yarovenko Hanna ,   Sumy State University,
            Ukraine; University Carlos III of Madrid, Spain, Perkhun Larysa ,   MHP SE,
            Ukraine
Published: July 2023

The purpose of the article is to assess the maturity of systems for counteracting
financial and cyber fraud with the view of their future integration at global-level. The
calculations made by the authors were based on indicators for 76 countries, which
characterized each country's level of cybersecurity and its ability to combat financial
fraud in 2018. After optimising the input data and selecting relevant indicators, the
authors built an integrated cybersecurity index using the Sundarovsky convolution
method. Sigma-limited parameterisation and Pareto-optimisation were then used to
identify the determinants of the ability to counter financial and cyber fraud, which
were used as predictors. Nonlinear regression was applied to determine the dependency of
the integrated cybersecurity index on the government efficiency index, the ease of doing
business and on the crime indices. On this basis, the authors conducted a bifurcation
analysis of the maturity of current global system for combating financial and cyber
fraud and produced its phase portraits. It was found to be mature (“Government
Efficiency Index – Ease of Doing Business” and “Ease of Doing Business – Crime Index”)
and insufficient mature (“Government Efficiency Index – Crime Index”), with the
components' imbalance indicating high system's sensitivity to react on changes. The
constructed 'Equilibrium States' phase portraits showed non-equilibrium phase portraits
of the 'saddle' type. The obtained results made it possible to identify determinants of
a global integrated system's instability to combat financial and cyber fraud.
Determinación de polifenoles en cinco especies amazónicas con potencial antioxidante
Authors: Radice Matteo , Bravo Sánchez Luis Ramón , Pérez Quintana Manuel , Cerda Grefa Jofre Bladimir , Tapuy Andrea , Riofrio Carrión Andrea , Neill David Alan , Chiurato Matteo
Published: July 2023

La Región Amazónica Ecuatoriana (RAE) representa una de las áreas del planeta más ricas en biodiversidad y una fuente de metabolitos secundarios para el sector farmacéutico, cosmético y de los alimentos funcionales. El resente estudio se enfoca, por primera vez, a la determinación de compuestos polifenólicos en extractos de cinco especies amazónicas: Caryodaphnopsis tomentosa, Palicourea stenostachya, Palicourea schunkei, Schizocalyx bracteosus y Warszewiczia coccinea. La actividad biológica de los polifenoles está relacionada con su carácter antioxidante y es relevante para la identificación de nuevos compuestos bioactivos. Los extractos hidroalcohólicos, considerando una variedad de vino tinto como referencia, han presentado, en cantidades diferentes, una notable presencia de polifenoles, aplicando la técnica de Folin-Ciocalteu. Los extractos de las especies C. tomentosa, S. bracteosus, W. coccinea y las hojas de P. stenostachya, han dado resultados superiores al doble del valor del patrón empleado. En los extractos de las raíces de P. stenostachya y de P. schunkei se han evidenciado valores de polifenoles totales ligeramente inferiores al patrón, sin embargo, se manifiesta una presencia importante de polifenoles que puede contribuir a su actividad antioxidante. Este resultado, aunque representa un ensayo preliminar, asienta un importante precedente para el estudio fitoquímico de las especies amazónicas mencionadas.
There is no future without Native and Black faculty in higher education
Authors: Tachine Amanda , Hailu Meseret
Published: July 2023

Using a letter-based methodology, we assert that higher education in the United States needs faculty members from Native and Black communities in order to be viable for presence and futures. We recognize that decolonization in higher education requires epistemological shifts that must be achieved by the people. Without people well-attuned to these epistemologies, such as critical Native and Black professors, this decolonization cannot happen. We also draw from extant literature and data from the National Center for Education Statistics to show how demographic disparities among faculty have been persistent over the past four decades. Throughout, we create a dialogue between decolonial and postcolonial literature. In doing so, we draw connections between these theories and education policies, practices, and pedagogies that advance more equitable and sustainable relationships in the relational flow of life where everyone and everything –both human and non-human–are deeply interconnected.
A Review of: “Algeria: Politics and Society from the Dark Decade to the Hirak”by Michael J. Willis
Authors: Szabó Zsolt
Published: July 2023

According to the author of the review, this work is considered to be one of the most important books on Algeria, North Africa and the MENA region in recent years. It is relevant, as it has been published in 2022 and it uses data from primary and secondary sources that are fresh and interesting in nature. The writer is an Oxford University professor, who has written already several books on the theme.
The author goes on to describe the book by first grading its quality concerning sources, materials and methods. Then the book is explored according to its eight chapters, by which the author consistently explores every aspect of the modern Algerian life from history to politics to economy and so on. The first chapter is about the early independence history of Algeria, the second comprises the terms of Bouteflika, the third chapter describes the islamist movements of the 1990s, the fourth chapter considers the politics and economy of the country, the fifth chapter turns to concentrate on the existing political opposition and its forms in Algeria, the sixth chapter examines Algerian politics and society, which is also an improtant factor, the seventh chapter focuses on restive regions (Kabylia, Mzab, Saharan South), while the eighth chapter's aim is to describe the country's position in the international community.
The book uses primary sources collected on the scene (2015-2017) and an impressive list of secondary sources listed in the bibliography at the end. Its style is fluent and regardless of some minor debatable issues, his findings are to be considered new in the research area of Algeria, the North African region, and the MENA region. The author finishes his review by confirming that he could only recommend this book to every reader or researcher who is interested in the topic or want to conduct research based on it.
Prediction of Pharmacokinetic Parameters from Ethanolic Extract Mane Leaves (Vitex pinnata L.) in Geothermal Manifestation of Seulawah Agam Ie-Seu’um, Aceh
Authors: Maulydia Nur Balqis , Khairan Khairan , Noviandy Teuku Rizky
Published: July 2023

The Mane plant (Vitex pinnata L.) is traditionally used as medicine in Aceh Province, Indonesia. This study aimed to predict the pharmacokinetic parameters of compounds in the ethanolic extract of Mane leaf (EEML), including the absorption, distribution, metabolism, excretion, and toxicity (ADMET), by in-silico approach. The method used was to analyze the compounds using a web-predictor server and molecular docking. Gas chromatography-mass spectrometry (GCMS) analysis of EEML showed the presence of active compounds, including phytol (60.93%), acorenol (8.56%), n-hexadecanoic acid (4.89%), trans-Z-alpha-bisabolene epoxide (2.7%) and cedrane (2.03%). Lipinski's rule of five states that all compounds had a deviation of less than 2. Pharmacokinetic parameters suggested that phytol was moderately absorbed in the gastrointestinal tract and had a toxicity level of 5 with lethal doses (LD50) >5000 mg/kg. Molecular docking results showed that phytol could be used against the targeted enzyme Staphylococcus aureus. In conclusion, our study suggests that the active compounds of EEML may have potential as a drug candidate.
Lesión renal como desenlace de enfermedad autoinmune tipo lupus eritematoso sistémico (les)
Authors: León Tacuri Miryam Anabel , Espinoza Moreira Silvia , Mora Reyna Mery Susana , Santos García Klever Javier
Published: July 2023

Esta investigación tiene como principal objetivo estudiar la lesión renal como desenlace de enfermedad autoinmune tipo Lupus Eritematoso Sistémico (LES). La misma, posee un enfoque cualitativo con diseño no experimental de alcance explicativo bajo la técnica de revisión bibliográfica y documental. Para ello, se efectuó una búsqueda exhaustiva y rigurosa de la literatura, empleando como instrumento las fichas bibliográficas, en las que se registró y organizó la información encontrada, tomando en cuenta criterios de selección. Los buscadores más destacados fueron: PUBMED, CINAHL, SCIELO, DIALNET, GOOGLE SCHOLAR, COCHRANE, SCOPUS. A partir de la búsqueda se obtuvo que: la nefritis lúpica (NL) es la afectación renal de mayor importancia; a nivel clínico la NL puede manifestarse a través de cualquier síndrome nefrológico que abarca desde mínimas alteraciones del sedimento urinario hasta patología renal crónica extrema. La biopsia renal es el examen más indicado para obtener el diagnóstico certero de NL conllevando a su identificación de acuerdo con la clasificación de la Sociedad Internacional de Nefrología y la Sociedad de Patología Renal ISN/RPS 2003 y el establecimiento del tratamiento adecuado que se planifica en función del compromiso clínico del paciente. Con lo antes expuesto se concluye que, la enfermedad autoinmune tipo lupus eritematoso sistémico (LES) puede desencadenar lesión renal con probabilidades de ameritar diálisis o trasplante renal. Frente a ello es clave un enfoque multidisciplinario en el manejo de esta lesión, implicando a reumatólogos, nefrólogos y otros especialistas, así se puede brindar un tratamiento integral que considere los aspectos médicos como los psicosociales.
Análisis del impacto del mantenimiento preventivo en el rendimiento de los equipos biomédicos
Authors: Mendoza Rodríguez Eddy Rigoberto , Zambrano Loor Jimmy Arturo
Published: July 2023

El buen funcionamiento de los establecimientos de salud y la prestación de servicios en condiciones de calidad, seguridad, higiene y comodidad para los pacientes, visitantes y personal requiere que los equipos biomédicos de los hospitales funcionen adecuadamente y para ello se le debe dan prioridad a la aplicación de estrategias y actividades para la atención preventiva de los mismos. El Objetivo fue analizar el mantenimiento preventivo presentes en los equipos médicos del Servicio de Emergencia y de la Unidad de Cuidados Intensivos (UCI) Guayaquil y su incidencia en la productividad, como materiales y métodos se planteó un enfoque cuantitativo el diseño no experimental de corte transversal con apoyo de una investigación documental. El método de análisis fue descriptivo e inferencial. La población estuvo conformada por 06 técnicos biomédicos, las técnicas fueron la entrevista y la observación y el instrumento el cuestionario de opciones de respuesta mixta. Se obtuvo como resultado que: el 50% de los equipos biomédicos tuvo entre 1 y 2 fallas, las cuales pararon el funcionamiento del equipo entre 1 y 5 días (66,6%), de los 20 equipos existentes en los servicios 11 (55%) requieren mantenimiento correctivo y el 45% mantenimiento preventivo, en conclusión, el mantenimiento preventivo constituye pieza fundamental para el buen funcionamiento de las actividades hospitalarias y más allá, aseguran la supervivencia de los usurario. La realización de un plan de mantenimiento preventivo permite identificar el estudio de oferta y demanda en los servicios de carácter crítico, diagnosticar las situaciones de mantenimiento que son aplicadas, y los niveles de depreciación
Estrategias metodológicas en gamificación: revisión sistemática de literatura en educación en el contexto iberoamericano
Authors: Guillén García Jéssica , Hermann Acosta Andrés
Published: July 2023

La gamificación es una estrategia de aprendizaje en el ámbito educativo-profesional tiene como fin conseguir mejores resultados. Como objetivo el presente artículo de investigación se realizó una revisión sistemática en torno a las estrategias metodológicas de gamificación aplicada en la educación en el contexto iberoamericano. Desde el punto de vista metodológico, se aplicara el método sintético con la aplicación de la técnica de revisión documental como instrumento la ficha de recolección de información, se acota que este estudio se basó en la literatura científica sobre la gamificación. Como fuentes de información se indagó en las bases de datos: Scielo, Redalyc, Scimago, Dialnet. La gamificación ha generado interés por parte de los docentes; donde se identificaron según los resultados de cómo la influye de manera positiva, incrementando el nivel académico en los estudiantes. Concluyendo, al establecer lineamientos estratégicos metodológicos para el uso y estudio; dando un mayor alcance en los resultados del aprendizaje, buscando así aumentar la motivación en los estudiantes; desarrollando y fortaleciendo el ámbito educativo, se entregó un listado de acceso del tema para investigadores que les interesa el tema
TENDENCIAS EN LA CONFIGURACIÓN Y EL FUTURO DE LA EDUCACIÓN SUPERIOR
Authors: Cevallos Villamarín Jessica Nicole
Published: July 2023

Este trabajo de investigación permite conocer las tendencias en la configuración y el futuro de la Educación Superior para examinar la situación que guarda la educación en el mundo actual, y analizar cómo la ES debe enfrentarse ante las nuevas realidades de la sociedad del conocimiento. Por lo tanto, se busca describir las tendencias con base en una investigación con diseño documental de los organismos multilaterales: ONU, UNESCO, OECD, entre otras. El análisis ha profundizado de un modo amplio la revisión teórica de las tendencias que están siguiendo los cambios en los Sistemas de Educación Superior a escala mundial. Los resultados de este estudio pusieron en evidencia la necesidad de abordar las tendencias de la ES como: la internacionalización, la movilidad académica, el aumento de la demanda, la transformación digital, el espíritu empresarial, las modalidades híbridas, la innovación pedagógica, el aprendizaje automático, la inteligencia artificial, el metaverso, la salud mental y la pertinencia de conocimientos; debido a ello se concluye que los Sistemas de Educación Superior deben implementar una cultura de calidad, para enfrentar a varios desafíos que están orientados a la búsqueda de la calidad y a los cuales deben responder, como es la competitividad en un mundo
EN BÚSQUEDA DEL GRAVITÓN: ANÁLISIS BIBLIOGRÁFICO DE LA HIPOTÉTICA PARTÍCULA ELEMENTAL
Authors: Méndez Mantuano Marcel
Published: July 2023

La gravedad es una fuerza fundamental que ha sido estudiada por los físicos durante siglos. En la física clásica, la gravedad se describe mediante la ley de gravitación de Newton, mientras que, en la relatividad general de Einstein, la gravedad se interpreta como la curvatura del espacio-tiempo causada por la presencia de materia y energía. No obstante, la descripción de la gravedad en el marco de la mecánica cuántica ha sido un desafío para los físicos teóricos. La teoría cuántica de campos predice la existencia de partículas elementales llamadas gravitones, que son los portadores de la fuerza gravitatoria. Los hipotéticos gravitones serían partículas bosónicas de spin-2, lo que significa que tienen dos unidades de momento angular intrínseco. Sin embargo, a diferencia de los fotones, que son bosones de spin-1 y mediadores de la fuerza electromagnética, los gravitones nunca han sido detectados directamente. La presente investigación tiene como objetivo examinar los fundamentos que dieron origen al concepto de gravitón, así como las características de esta partícula, los experimentos llevados a cabo en su búsqueda y las posibles alternativas teóricas a su existencia. Se llevó a cabo una revisión bibliográfica exhaustiva de las fuentes que originaron la idea del gravitón, seguida de una síntesis de los postulados, sin profundizar en las nociones matemáticas que sustentan dichos principios. Finalmente se concluye que la detección de los gravitones tendría importantes implicaciones para la física teórica y la comprensión del universo, lo cual, podría proporcionar un entendimiento más profundo de la naturaleza de la gravedad y la forma en que interactúa con otras fuerzas fundamentales de la naturaleza.
Pandémie de rougeole, 1988-1992
Authors: Monnais Laurence
Published: July 2023

Au tournant des années 1990, la rougeole a balayé le monde. Évitable par la vaccination depuis 1963, la « première maladie » est pourtant une des grandes absentes d’un siècle pandémique qui tarde à s’achever, si ce n’est pour en faire l’incarnation d’un anti-vaccinationisme rampant. Au travers d’une chronique de la « crise » de 1988-1992, nous reviendrons sur le processus decoproductionentre l’infection et les technologies qui en protègent. Nous aborderons plus particulièrement la dimension sociale de l’infection virale pour comprendre pourquoi la vaccination de masse, au coeur d’une entreprise d’éradication appuyée, ne suffit pas à éviter la rougeole et participe même à accroître certaines inégalités en santé qui influent sur son épidémiologie. L’expérience de la COVID‑19 nous exhorte à mener ce genre de travail rétrospectif et à mobiliser l’Histoire en discipline de santé publique pour mieux saisir la place de la vaccination dans le passé et le présent viraux et contagieux.Documentation de l’OMS, littérature scientifique et terrain ethnographique forceront ensemble une approche « à parts égales » des espaces et des acteurs concernés, faisant dialoguer les expériences très locales et les politiques internationales pour révéler les écueils d’une santé (publique) globale ultra-technologisée et très verticale.
Les étudiantes et étudiants et le mouvement indien des femmes à New Delhi
Authors: Michon Caroline
Published: July 2023

L’étude des étudiantes et étudiants engagés dans les luttes féministes et/ou pour l’égalité au sein de deux campus de la ville de New Delhi laisse entrevoir les débats actuels qui traversent le mouvement indien des femmes. Ce mouvement historique, composé de femmes et d’hommes luttant pour l’égalité en Inde, a éclos à la fin du XIXe siècle et a connu plusieurs périodes et générations de militantes portant des problématiques propres. Les étudiantes et étudiants sont des acteurs centraux des luttes du fait de leurs revendications et des débats qu’elles et ils suscitent. L’institutionnalisation du genre, la reproduction des inégalités et l’invisibilité de certaines problématiques qui sont au coeur des luttes sur les campus font écho aux luttes internes du mouvement. Tout en étant les héritiers des luttes passées, les étudiantes et étudiants semblent appartenir à une nouvelle génération de féministes naviguant entre idéologie intersectionnelle, demande d’autonomie et reproduction sociale.
Acte alimentaire, normativité sociale et diabète de type 2 chez des migrants originaires d’Afrique subsaharienne
Authors: Mandiangu Ntanda Gisèle , Roy Bernard , Tremblay Marie-Claude
Published: July 2023

Depuis longtemps, l’avènement du diabète de type 2 est associé aux comportements alimentaires. Il s’agit, d’ailleurs, d’un des comportements les plus ciblés par les intervenants de la santé pour que les personnes vivant avec le diabète de type 2 retrouvent la santé. Ces personnes sont, individuellement, invitées à choisir minutieusement les aliments qu’elles incluent dans leur alimentation quotidienne tout en respectant les valeurs nutritives, des apports caloriques scientifiquement normés. Cette conception de l’alimentation occulte les dimensions sociales, voire identitaires, de l’acte alimentaire. À partir des données préliminaires issues de notre recherche doctorale s’intéressant aux personnes originaires de l’Afrique subsaharienne porteuses d’un diagnostic de diabète de type 2 ou à risque de développer cette pathologie, nous souhaitons démontrer que l’acte alimentaire constitue une puissante manifestation d’une normativité sociale. Celle-ci permet de créer de solides liens sociaux au sein des collectivités de personnes partageant des histoires de vie, des postures sociales, économiques et politiques apparentées.
Récits, dialogues et dialogisme à l’École
Authors: Carcassonne Marie
Published: July 2023

Cet article s’inscrit dans un numéro dans lequel les différents auteurs montrent
comment la pensée de François a nourri leurs analyses dans le champ de la didactique du
français langue maternelle. Il explique en quoi la notion dialogique de «mouvement» (de
«continuité-déplacement» ou «reprise-modification») au sens de François joue un rôle dans la
circulation et le renouvellement des discours et des savoirs, ainsi que dans leur
appropriation. Pour préciser la façon dont cette notion de mouvement éclaire ce qui se passe
dans des situations d’enseignement-apprentissage à l’École, quelques exemples relatifs à
deux activités langagières (restitutions de récits et argumentation) sont
convoqués.
« Clore Avril. » Le deuil de la révolution dans Bon peuple portugais de Rui Simões et Gestes et fragments d’Alberto Seixas Santos
Authors: Robert-Gonçalves Mickaël
Published: July 2023

Au début des années 1980, deux films, Bon peuple portugais (1981) de Rui Simões et Gestes et fragments (1982) d’Alberto Seixas Santos, sont finalisés au Portugal dans des circonstances difficiles ; quelques années seulement après la Révolution portugaise de 1974-1975, il semblait incomber à ces deux projets de représenter le « deuil » de cette période révolutionnaire. Ce texte interroge ainsi la place de ces deux films-essais dans le cinéma portugais de l’époque. Capables d’interroger la mémoire encore vive de l’événement et d’intervenir dans l’écriture possible de cette histoire, les deux projets mettent plus particulièrement en perspective la figure d’Otelo Saraiva de Carvalho, qui apparaît comme une icône ambiguë de cette dernière révolution romantique d’Europe.
Evaluating the induced photon contamination by different breast IOERT shields using Monte Carlo simulation
Authors: Baghani Hamid Reza , Robatjazi Mostafa
Published: July 2023

Background and Objective

Avoiding the underlying healthy tissue over‐exposure during breast intraoperative electron radiotherapy (IOERT) is owing to the use of some dedicated radioprotection disks during patient irradiation. The originated contaminant photons from some widely used double‐layered shielding disks including PMMA+Cu, PTFE+steel, and Al+Pb configurations during the breast IOERT have been evaluated through a Monte Carlo (MC) simulation approach.

Methods

Produced electron beam with energies of 6, 8, 10, and 12 MeV by a validated MC model of Liac12 dedicated IOERT accelerator was used for disk irradiations. Each of above‐mentioned radioprotection disks was simulated inside a water phantom, so that the upper disk surface was positioned at R90 depth of each considered electron energy. Simulations were performed by MCNPX (version 2.6.0) MC code. Then, the energy spectra of the contaminant photons at different disk surfaces (upper, middle, and lower one) and relevant contaminant dose beneath the studied disks were determined and compared.

Results

None of studied shielding disks show significant photon contamination up to 10 MeV electron energy, so that the induced photon dose by the contaminant X‐rays was lower than those observed in the disk absence under the same conditions. In return, the induced photon dose at a close distance to the lower disk surface exceeded from calculated values in the disk absence at 12 MeV electron energy. The best performance in contaminant dose reduction at the energy range of 6–10 MeV belonged to the Al+Pb disk, while the PMMA+Cu configuration showed the best performance in this regard at 12 MeV energy.

Conclusion

Finally, it can be concluded that all studied shielding disks not only don't produce considerable photon contamination but also absorb the originated X‐rays from electron interactions with water at the electron energy range of 6–10 MeV. The only concern is related to 12 MeV energy where the induced photon dose exceeds the dose values in the disk absence. Nevertheless, the administered dose by contaminant photons to underlying healthy tissues remains beneath the tolerance dose level by these organs at the entire range of studied electron energies.
Ultra‐Flexible Monolithic 3D Complementary Metal‐Oxide‐Semiconductor Electronics
Authors: Zhang Jiaona , Wang Wanting , Zhu Jiahao , Wang Jialiang , Zhao Changbin , Zhu Tianyu , Ren Qinqi , Liu Qi , Qiu Rui , Zhang Min , Wang Xinwei , Meng Hong , Chang Kuan‐Chang , Zhang Shengdong , Chan Mansun
Published: July 2023

Flexible electronics based on complementary metal‐oxide‐semiconductor (CMOS) technology have enabled a smart soft world. However, the trade‐off among flexibility, density, and electrical performance has been a long‐lasting unresolved issue. Here, a monolithic three‐dimensional (M3D) CMOS design is proposed to address this problem and realize ultra‐flexible electronics with high electronic‐performance and integration. This design utilizes vertically stacked p‐type carbon nanotube transistors and n‐type indium gallium zinc oxide ones, which share common gates and drains, saving the inter tier vias required in the traditional M3D structure to reduce routing and improve flexibility. With this design, CMOS logic gates, multi‐stage circuits, ring oscillators (ROs) and memory modules, are demonstrated. This design enables circuits to save up to 45% of area compared with their planar counterparts. Particularly, inverters exhibit a record‐high gain of 191, and 55‐stage ROs can operate well even after bending at a 500‐µm radius for 50 cycles, exhibiting the highest flexibility among the reported ones. The ultra‐flexible and high‐integration RO enables a wearable light recorder to collect harmful blue light shining into human eyes by simply attaching the circuits on a contact lens. This integration method provides possibilities for developing complex‐function wearable electronics.
Synthesis and characterization of aromatic copolyesters derived from bisphenol B and phenol red
Authors: Wang Zhoufeng , Hu Junwei , Wang Bolin , Liu Yingying , Long Xiubo
Published: July 2023

A series of novel aromatic copolyesters derived from bisphenol B (BPB) and phenol red (PR) were synthesized by interfacial polymerization. The number‐ and weight‐average molecular weight (Mn and Mw) of the obtained amorphous aromatic copolyesters ranged from 1.06–1.80 × 104 to 2.01–6.17 × 104 g/mol, respectively. Density functional theory calculations showed that the reactivity of BPB was similar to that of bisphenol A. The reaction activation energy of BPB with terephthaloyl and isophthaloyl chloride (TPC and IPC) was 8.23 kcal/mol, and PR with IPC and TPC was 59.30 kcal/mol. Under the influence of the ethyl side group of BPB and the pendant group of PR, the solubility of the aromatic copolymer was improved, and the glass transition temperature (Tg) was 125.1–195.3°C, while Tmax could still be maintained above 525.72°C. The optical transmittance of the copolyesters at 450 nm (T450) was 69.29%–99.41%, and the tensile strength and Young's modulus were in the range of 46.79–58.59 MPa and 1.39–1.86 GPa respectively. All aromatic copolyesters exhibit good mechanical and processability properties and have great application potential as high‐performance plastics.
The mood effect: How mood, disclosure language and ad skepticism influence the effectiveness of native advertising
Authors: Wen Taylor Jing , Wu Linwan , Dodoo Naa Amponsah , Kim Eunice
Published: July 2023

This research investigated the interplay between mood, disclosure language, and ad skepticism on consumers' recognition and evaluation of native advertising. During two online experiments, participants first received a mood manipulation and then read an article‐style native advertisement. Results from both studies indicated that participants were more likely to recognize a native ad with an explicit rather than an implicit disclosure label, and a negative mood was more likely than a positive mood to drive participants to recognize the native ad. More importantly, participants in a positive mood evaluated a native ad with an implicit disclosure more favorably than an ad with an explicit disclosure. By contrast, participants in a negative mood responded more positively to a native ad with explicit disclosure compared to an ad with implicit disclosure. Study 2 demonstrated that the interaction between mood and disclosure language was further moderated by individuals' levels of ad skepticism. These results are believed to provide meaningful theoretical and practical implications to the field of native advertising and consumer behavior.
A case of high‐risk AML in a patient with advanced systemic mastocytosis
Authors: Fazio Manlio , Vetro Calogero , Markovic Uroš , Duminuco Andrea , Parisi Marina , Maugeri Cinzia , Mauro Elisa , Parrinello Nunziatina Laura , Stagno Fabio , Villari Loredana , Triolo Anna Maria , Stella Stefania , Palumbo Giuseppe A. , Di Raimondo Francesco , Romano Alessandra , Zanotti Roberta
Published: July 2023

Aggressive SM + AML has limited therapeutic options. Even a strong combination of decitabine–venetoclax–midostaurin has a transient effect on AML and a mitigated effect on SM. Larger series are required to identify the best therapeutic strategy.
Genetic characterization of FODMAPs and ATIs in heritage and modern spring wheat
Authors: Bajgain Prabin , Boakye Prince G. , Kougblenou Ibilola , Murai Takehiro , Annor George A. , Anderson James A.
Published: July 2023

The fermentable oligo‐, di‐, and monosaccharides and polyols (FODMAPs) and amylase–trypsin inhibitors (ATIs) present in wheat flour can trigger irritable bowel syndrome (IBS) symptoms and intestinal inflammation. Lowering FODMAPs and ATIs concentrations in wheat flour could make the grain accessible to humans with IBS. This study evaluated a diverse panel of heritage and modern spring wheat lines for FODMAPs and ATIs concentrations and carried out a genome‐wide association analysis. A moderately strong population structure was observed as the first two principal component axes explained 10.9% of the genotypic variation, and lines grouped into three clusters. Trait correlations within and across locations ranged from −0.33 to 0.87. Broad‐sense heritabilities ranged from 0.30 to 0.67. Evaluation of 33 varieties released by the University of Minnesota between 1915 and 2020 revealed no significant changes over time in ATIs or FODMAPs concentrations. Association analysis resulted in detection of 38 quantitative trait loci (QTL) in 12 chromosomes and three of the 38 QTL were common between two traits in the St. Paul location. The QTL were of small to medium effect as the range of explained phenotypic variation was 4.9%–11.8%. There was no overlap among the QTL regions reported in this research compared with those reported from previously published studies. Genomic prediction models predicted the traits with low to moderate trait correlations that ranged from 0.13 to 0.34. Discovery of markers associated with FODMAPs and ATIs, in conjunction with a genome‐wide selection strategy, could aid in selection of breeding lines with desirable concentrations of these compounds.
Developing a Human Performance Model Based Systems Engineering System Architecture (MBSE‐SA) for Defense Applications
Authors: Sarathi Tara , Cyr Jillian , Morris Heather , DeLaura Rich , Balcius James , Collins Paula , Shatz Michael
Published: July 2023

The military has limited means to objectively evaluate soldier and squad performance, leading to sub‐optimal operational, training, and acquisition decisions. Part of this limitation stems from the fact that the ability to monitor, predict, and enhance soldier and squad performance is a complex System of Systems (SoS) undertaking. To address this integration challenge, we developed a comprehensive conceptual framework that maps mission‐level success to measures of task effectiveness and human performance that quantify the impact of emerging technologies and interventions. In addition, by leveraging lessons learned from a previous effort that developed a Wearables MBSE system architecture (MBSE‐SA) and methodology for military health monitoring systems, we developed a Human Performance MBSE‐SA to capture and apply the conceptual framework, which provides the foundation for several system‐level and program‐level analyses, including gap identification. This paper presents the Human Performance MBSE‐SA and an illustration of its utility in showing the connections among ongoing military research efforts, strategic source requirements, and operational use cases.
Investigating Systems Engineering Approaches in the Norwegian Construction Industry: A Multi‐Case Study
Authors: Lynghaug Tobias Fredrik , Kokkula Satyanarayana , Muller Gerrit
Published: July 2023

There is an increasing application of Systems Engineering in the Norwegian construction industry. This paper investigates the effects of a Systems Engineering approach on project management performance, prerequisites for success, and which elements contribute to effectiveness from a technical contractor perspective. First, we find a positive perception of Systems Engineering's effect on time, cost, and quality. Second, we provide and rank a list of 12 prerequisites for success. Third, we quantify the perceived importance of five elements of the systems engineering process. Finally, we find a disconnect between what seems to be essential processes and prerequisites and what gets done in practice. To improve Systems Engineering performance, we recommend improving Systems Engineering competence and capabilities, increasing the formality of requirements analysis and documentation, and front‐loading the effort and allocation of resources in projects.
Git‐based Model Management for Quality Monitoring of Systems Engineering Models
Authors: Lehner Daniel , Vamberszky Simon , Wieland Konrad , Siegl Daniel
Published: July 2023

The management of Systems Engineering Models is becoming a crucial requirement when developing complex systems. Particularly with the advance of agile MBSE, Systems Engineering Models evolve constantly. Therefore, for managing Systems Engineering Models, this evolution has to be supported, including concurrent work on one model. Therefore, Git‐based solutions are emerging nowadays also in the Systems Engineering domain. Dedicated model differencing and conflict resolution approaches are provided by extensions of the base support of Git, which is mostly oriented to textual artefacts. However, the monitoring and management of the System Engineering Models hosted in Git repositories is still an open challenge. In this paper, we present a Git‐based model management approach for monitoring the quality of Systems Engineering Models. We outline the architecture of the approach as well as the proposed Git‐based model management approach and discuss the realization based on Enterprise Architect and LieberLieber LemonTree. In addition, we demonstrate the approach by a running example and outline future directives.
The association between sonographic common bile duct dilatation and outcomes in emergency department patients with cholangitis
Authors: Rotter Ayelet , Granat Nadav , Koslowsky Benjamin , Bdolah‐Abram Tali , Schwartz Alon D. , Alpert Evan Avraham
Published: July 2023

Background

The presentation of the patient with acute cholangitis (AC) ranges from mild illness to life‐threatening shock. Therefore, prompt diagnosis and treatment are critical. Abdominal ultrasound (US) is the imaging of choice to locate bile duct dilatation. Other modalities include abdominal computed tomography (CT) or endoscopic retrograde cholangiopancreatography (ERCP).

Objectives

To determine whether sonographic common bile duct dilatation in emergency department (ED) patients with AC predicts outcomes including sepsis, hospital length of stay (LOS), admission to the intensive care unit (ICU), time to ERCP, and mortality.

Methods

Electronic medical records of all patients hospitalized in a tertiary care medical center between July 2012–February 2021 with a discharge diagnosis of cholangitis were assessed. Patients were dichotomously classified as CBD dilated or CBD non‐dilated based on ultrasound. Dilation was defined as CBD larger than 6 mm in patients younger than 60 or larger than 6 mm + 1 mm per decade in patients over 60.

Results

The study included 271 patients‐ 172 with CBD dilation versus 99 without. Mean LOS was 9.92 days for those with a dilated CBD versus 13.4 days without. The mean time to ERCP was 4.26 days for those with a dilated CBD versus 6.56 days without. Sepsis, mortality, and ICU admission were scarce and there was no statistically significant difference between the cohorts.

Conclusion

Patients with a dilated CBD per the abdominal US performed during the patient's ED stay, underwent ERCP earlier, and were hospitalized fewer days than patients without CBD dilation.
French dermatologists' opinions and practices with regard to adjuvant therapy in stage III melanoma
Authors: Rolland Marion , Oger Emmanuel , Dinulescu Monica , Lesimple Thierry , Russo David , Pracht Marc , Porneuf Marc , Dalac Sophie , Giacchero Damien , Jouary Thomas , Lebbé Celeste , Leccia Marie-Thérèse , Maubec Eve , Meyer Nicolas , Mortier Laurent , Dupuy Alain
Published: July 2023

Background

In 2018, the European Medicines Agency authorized adjuvant therapy for patients with resected stage III melanoma.

Objectives

The objective of the present study (performed in France) was to assess dermatologists' and oncologists' opinions and prescribing habits in this context.

Methods

From 28 May to 8 June 2021, we performed an online survey of members of the French Groupe de Cancérologie Cutanée (GCC) skin cancer interest group.

Results

Thirty‐eight practitioners replied to the survey. For BRAF‐mutant melanoma, 58% of the practitioners favoured immunotherapy (IT). If they themselves were to suffer from melanoma with a BRAFV600 mutation, 65% would choose IT for stage IIIB disease, and 72% would choose IT for stage IIID disease. For stage IIIA melanoma with a positive sentinel lymphatic node (SLN) biopsy <1 mm, 32% of the practitioners stated that they would not offer adjuvant therapy. Sixty‐three percent of the practitioners disagreed with restricting adjuvant therapy to patients aged 80 and over. Although 84% of the practitioners were aware of the cost of adjuvant therapy, 81% did not take account of this factor in their treatment decisions. In patients with a positive SLN biopsy, 90% of the practitioners stated that they would not recommend complete lymph node dissection. Eighty percent of the surveyed practitioners discussed the potential impact of treatments on fertility, respectively with their male and female patients. Of these practitioners, 63%–72% (depending on the situation) stated that they would recommend fertility preservation procedures.

Conclusions

This work points out some debated issues among French dermatologists and oncologists regarding adjuvant therapy in stage III melanoma. Our present results might prompt more comprehensive studies of these particular points.
What do people affected by amyotrophic lateral sclerosis want from health communications? Evidence from the ALS Talk Project
Authors: Genuis Shelagh K. , Luth Westerly , Bubela Tania , Johnston Wendy S.
Published: July 2023

Introduction/Aims

Health communication is central to effective, supportive amyotrophic lateral sclerosis (ALS) clinical care. Guidance for ALS communication is limited, focuses on diagnosis disclosure, and frequently relies on expert consensus and/or reviews. Patient‐based evidence is needed to guide ALS health communication. We investigated how the experiences of ALS patients and family caregivers can inform effective communication practices from diagnosis to end‐of‐life.

Methods

Data were drawn from the ALS Talk Project, an asynchronous, online focus group study. Seven focus groups and five interviews (105 participants) were conducted. Data were qualitatively analyzed using directed content analysis and the constant‐comparative approach.

Results

We found four primary themes: communication content, communication circumstances, information sufficiency, and communication manner. Data indicate participants relied on clinicians for medical information but also wanted practical information; health communication should attend to the circumstances within which conversations occur; information must be sufficient for individual needs, without overwhelming; and an empathetic, direct, and honest manner facilitated trust. Participants identified communication challenges and strategies to improve communication across major themes, including stepwise approaches and conversations tailored to individuals and their heterogeneous disease experiences.

Discussion

Healthcare professionals should discuss patient/caregiver communication preferences early in the therapeutic relationship, co‐develop a communication agreement, and update the agreement in response to changing needs and disease progression. This will foster regular discussion of information needs and promote timely discussions of challenging topics, including advance care, while giving patients and families a sense of control. Findings may have implications for other neuromuscular disease and/or seriously ill populations.
An effective case of bronchoscopic balloon dilatation for tuberculous bronchial stenosis
Authors: Ichikawa Yukari , Kurokawa Koji , Furusho Shiho , Nakatsumi Yasuto , Yasui Masahide , Katayama Nobuyuki
Published: July 2023

Endobronchial tuberculosis often causes bronchial stenosis. Balloon dilation is a minimally invasive and effective bronchoscopic intervention for bronchial stenosis; however, reports on balloon dilation in older individuals are limited. We present a case of a 77‐year‐old woman with endobronchial tuberculosis and clarify the efficacy and safety of balloon dilation. She presented with dyspnea, right lung atelectasis, and respiratory failure 55 days after initiation of antituberculosis therapy. We performed bronchoscopic balloon dilatation for the right main bronchial stenosis. Consequently, respiratory failure rapidly improved. Chest computed tomography (CT) showed improved lung atelectasis; however, severe bronchial stenosis and rhonchi persisted. Therefore, we performed a second balloon dilatation. CT 3 months after the first balloon dilation showed right upper bronchial stenosis and right lung middle lobe atelectasis. Restenosis was absent 21 months after third balloon dilatation. Bronchoscopic balloon dilation is effective for restenosis with repeated treatment and can be safely performed in older individuals.
Terrain‐derived measures for basin conservation and restoration planning
Authors: Matt Jeremy E. , Underwood Kristen L. , Diehl Rebecca M. , Lawson K. S. , Worley Lindsay C. , Rizzo Donna M.
Published: July 2023

Centuries of human development have altered the connectivity of rivers, adversely impacting ecosystems and the services they provide. Significant investments in natural resource projects are made annually with the goal of restoring function to degraded rivers and floodplains and protecting freshwater resources. Yet restoration projects often fall short of their objectives, in part due to the lack of systems‐based strategic planning. To evaluate channel‐floodplain (dis)connectivity and erosion/incision hazard at the basin scale, we calculate Specific Stream Power (SSP), an estimate of the energy of a river, using a topographically based, low‐complexity hydraulic model. Other basin‐wide SSP modeling approaches neglect reach‐specific geometric information embedded in Digital Elevation Models. Our approach leverages this information to generate reach‐specific SSP‐flow curves. We extract measures from these curves that describe (dis)connected floodwater storage capacity and erosion hazard at individual design storm flood stages and demonstrate how these measures may be used to identify watershed‐scale patterns in connectivity. We show proof‐of‐concept using 25 reaches in the Mad River watershed in central Vermont and demonstrate that the SSP results have acceptable agreement with a well‐calibrated process‐based model (2D Hydraulic Engineering Center's River Analysis System) across a broad range of design events. While systems‐based planning of regional restoration and conservation activities has been limited, largely due to computational and human resource requirements, measures derived from low‐complexity models can provide an overview of reach‐scale conditions at the regional level and aid planners in identifying areas for further restoration and/or conservation assessments.
Extremitätenerhaltende Resektion von Weichteilsarkomen in der Regio axillaris
Authors: Stauss Ricarda , Graulich Tilman , Omar Pacha Tarek , Omar Mohamed
Published: July 2023

Operationsziel

Tumoren mit Lokalisation in der Regio axillaris stellen durch die enge anatomische Beziehung zu neurovaskulären Strukturen eine besondere Herausforderung für die Resektion dar. Operationsziel ist die R0-Resektion unter Wahrung eines maximalen Funktionserhalts.

Indikationen

Weichteilsarkome, Metastasen.

Kontraindikationen

Fortgeschrittene Stadien mit Infiltration neurovaskulärer Strukturen, Lokalisation des Biopsietrakts erfordert ausgedehnte Resektion, palliative Behandlungssituation.

Operationstechnik

Erweiterter deltoideopektoraler Zugang. Ansatznahes Ablösen des M. pectoralis major et minor. Präparation der Vasa axillaria und der Faszikel des Plexus brachialis. Ligatur der in den Tumor eintretenden Gefäße. Tumorresektion, Fadenmarkierung. Rekonstruktion mittels transossärer Reinsertion des M. pectoralis minor am Processus coracoideus. Setzen von Bohrkanälen und transossäre Refixation des M. pectoralis major am Humerus.

Weiterbehandlung

Schulterabduktionskissen für 6 Wochen, passive Mobilisation Woche 6 bis 12, dann aktive Mobilisation. Kompressionsorthese. Onkologische Nachsorge.

Ergebnisse

Zwischen 2017 und 2022 erfolgte in 6 konsekutiven Fällen (4 primäre Weichteilsarkome, 2 Metastasen) die chirurgische Resektion. In 100 % der Fälle wurde eine primäre R0-Resektion erreicht. Das mittlere Follow-up lag bei 22,5 Monaten (3 bis 60 Monate), im gesamten Nachuntersuchungszeitraum traten keine Lokalrezidive auf. Der durchschnittliche Bewegungsumfang für die Abduktion im Schultergelenk lag bei 135,0 ± 41,4° (Range 90–180°). Es traten keine postoperativen sensomotorischen Defizite auf. Die subjektive Schulterfunktion lag bei 80,0 ± 21,0 % (Range 50–100 %). Der mittlere MSTS-Score lag bei 89,5 % (Range 32–100 %) und belegt somit ein gutes funktionales Outcome.