bluuebunny/crossref_metadata_2025 huggingface dataset:
Energy Management Strategy for Dc Micro-grid System With an Important Penetration of Renewable Energy
Authors: Bipongo Christian Ndeke , Adonis Marco , Almaktoof Ali
Published: July 2023

This paper presents an energy management strategy using stateflow controller related to DC micro-grids with an important penetration of renewable energy. The increase in world electricity demand is one of the principal drivers of the exhaustion of fossil fuels and expanded greenhouse gas emissions. To solve these problems, several countries have adopted actions for large renewable energy deployment, which includes wind energy, solar power, biomass power, tidal, and hydropower. These sources are considered as significant in delivering clean energy and reducing greenhouse gas emissions for sustainable improvement. In such a case, these are referred to as distributed generation systems. Distributed generation can impact negatively on the performance of the distribution network as the distribution network will no longer operate with a unidirectional power flow pattern. To address these issues, micro-grids are being used as a platform to integrate distributed generation systems, as they provide significant benefits to end-users and to the distribution network. The objective of this paper was to implement an energy management system to ensure the proper operation of the developed DC microgrid and this was developed using Simulink blocks available in the MATLAB/Simulink software. The simulation results shown that this control strategy is unconditionally reliable to ensure proper operation of the microgrid systems. Moreover, the developed algorithm model presents another advantage, which enables the users to access and to change any control parameters within the DC microgrid. By comparing these results with the literature, the developed energy management algorithm provides safety and automatic control of the microgrid.
Birthweight Trends and their Explanatory Factors in Hungary between 1999 and 2018: An Analysis of the Hungarian Tauffer Registry
Authors: ZSIRAI László , KUN Attila , VISOLYI Gergely Á. , SVÉBIS Márk M. , DOMJÁN Beatrix A. , Tabák Ádám Gy.
Published: July 2023

Background
The increasing birthweight trend stopped and even reversed in several high income countries in the last 20 years, however the reason for these changes is not well characterized. We aimed to analyze the birthweight trends of term deliveries and their potential maternal and fetal drivers in Hungary.
Methods
We analyzed data from the Hungarian Tauffer registry, a compulsory anonymized data collection of each delivery. We included all singleton term deliveries between in 1999-2018 (n=1 591 932). We modeled birthweight trends separately in 1999-2008 and 2008-2018 in hierarchical multiple linear regression models adjusted for calendar year, newborn sex, maternal age, gestational age at delivery, and other important determinants.
Results
Median birthweights increased from 3250/3400g (girl/boy) to 3300/3440g from 1999 to 2008 and decreased to 3260/3400g in 2018. When we adjusted for gestational age at delivery the increase in the first period became more pronounced (5.4 g/year). During the second period, similar adjustment substantially decreased the rate of decline from 2.5 to 1.4g/year. Further adjustment for maternal age halved the rate of increase to 2.4g/year in the first period. During the second period, adjustment for maternal age had little effect on the estimate.
Conclusions
Our findings of an increasing birthweight trend (mostly related to the aging of the mothers) in 1999-2008 may forecast an increased risk of cardiometabolic diseases in offsprings born in this period. In contrast, the decreasing birthweight trends after 2008 may reflect some beneficial effects on perinatal morbidity. However, the long-term effect cannot be predicted, as the trend is mostly explained by the shorter pregnancies.
Automated image quantification of immunohistochemistry-stained immune cells in triple-negative breast cancer
Authors: Roostee Suze , Ehinger Daniel , Jönsson Mats , Staaf Johan , Aine Mattias
Published: July 2023

Background:
Breast cancer is a molecularly heterogenous disease for which the composition of the tumour microenvironment (TME) is acknowledged with an increasing role in treatment response and prognosis. In triple-negative breast cancer (TNBC) tumour infiltrating lymphocytes (TILs), representative of a general immune response, have been associated with a favourable prognosis. With growing number of TME cell type markers being analysed by conventional IHC or other in situ methods combined with need of spatial marker relationship analysis digital image analysis tools are needed to facilitate broader in situ characterisation of the breast cancer TME.
Methods:
A TMA comprising 218 patients with TNBC, enrolled in the Sweden Cancerome Analysis Network – Breast (SCAN-B) study, with complementary clinicopathological, WGS, and RNA-sequencing data were used. The TMA was stained using immunohistochemistry for p53, CD3, CD4, CD8, CD20, CD68, FOXP3, and PD-L1 (SP142 antibody), with available pathology scoring for CD20, PD-L1 and TILs. An open-source digital image analysis pipeline, Tissue microarray MArker Quantification (TMArQ), for analyses of single marker IHC images was developed implementing starDist segmentation. Primary pipeline output was the number of positive cells based on IHC staining.
Results:
TMArQ’s cell counts for analysed immune markers were on par with results from more advanced trained machine learning algorithms and consistent with both estimates from human pathology review, different quantifications/classifications derived from RNA-sequencing as well as known prognostic patterns of immune response in TNBC. When combined with somatic genetic information (TP53-mutation and homologous recombination deficiency, HRD) the pipeline demonstrated consistency in p53 protein expression versus TP53 variant type and superior patient outcome for the combination of high CD3 counts with HRD-positivity in patients with adjuvant standard-of-care chemotherapy.
Conclusions:
TMArQ is an easy-to-use open-source automated pipeline for IHC-based cell detection and quantification to be used as an exploratory tool in cancer image analysis. Digital analysis tools will likely greatly facilitate further characterisation of the breast cancer TME in novel ways and allow for a more precise linking of TME features and molecular alterations detected by large-scale omics methods, thereby deepening our understanding of breast cancer.
Ex vivo susceptibility and molecular signature assessment of antimalarial-based combination therapies (ACT) partner drugs resistance in Senegal
Authors: YADE Mamadou Samb , Fall Awa , Coppée Romain , Mbaye Aminata , Adoux Lucie , Diallo Mamadou Alpha , Diongue Khadim , Tine Abdoulaye , Mama Atikatou , Thiaw Alphonse Birane , Bailly Justine , Ndiaye Ibrahima Mbaye , Kébé Ousmane , Sow Djiby , Ndiaye Tolla , Diédhiou Younouss , Gaye Amy , Doderer-Lang Cécile , Niyomwungere Denis , Tarama Casimire Wendlamita , Garba Mamane Nassirou , Bei Amy Kristine , Dièye Baba , Ménard Didier , Ndiaye Daouda
Published: July 2023

Background
Over the last decades, Plasmodium falciparum – the main causative agent of malaria – has constantly developed resistance to antimalarial drugs such as chloroquine, sulfadoxine-pyrimethamine or artemisinin derivatives. Therefore, active surveillance in the ex vivo susceptibility to the antimalarial drugs used as partner drugs in artemisinin-based combination therapies (the current frontline antimalarial) such as amodiaquine, lumefantrine or piperaquine, is essential.
Methods
Here, we evaluated the ex vivo susceptibility, expressed with the ex vivo SYBR™ Green, to six antimalarial drugs (amodiaquine, chloroquine, lumefantrine, mefloquine, piperaquine and quinine) from 34 P. falciparum isolates collected in 2018 in Thiès (Senegal). Whole-genome sequencing (WGS) was used to search for mutations in P. falciparum genes known to be associated with drug resistance.
Results
P. falciparum isolates showed reduced ex vivo susceptibility only to chloroquine (16% of the isolates). Mutations in pfcrt K76T (21%) and pfmdr1 Y184F (53%) were the most prevalent. A significant correlation was observed between the mutants pfcrt 76T and pfmdr1 184F and IC50 values for chloroquine. A significant decrease in ex vivo susceptibility to chloroquine and quinine associated with the pfcrt R371I was also detected (P < 0.001).
Conclusion
Our results suggest that the ex vivo susceptibility of P. falciparum isolates to amodiaquine, lumefantrine, mefloquine, piperaquine and quinine remains high in Thiès. Directly measuring ex vivo parasite drug response and sequencing resistance mutations overtime are both useful tools for monitoring parasite drug response in field samples.
Taş Alası (Salmo Trutta Macrostigma) Balığının Moleküler Gastronomi Teknikleri ile Pişirilmesi (Cooking of Taş Alası (Salmo Trutta Macrostigma) Fish With Molecular Gastronomy Techniques)
Authors: KUTAL Ünalcan , ŞEKER İbrahim Tuğkan
Published: July 2023

Günümüzde hızla değişen ve gelişen rekabet ortamı, gastronomi alanında birçok yeni akımı ortaya çıkarmıştır. Gastronomide yeni akımlar incelendiğinde moleküler gastronomi uygulamaları yaygın olarak karşımıza çıkmaktadır. Bu çalışma kapsamında moleküler gastronomi anlayışı benimsenerek taş alası balığına farklı pişirme tekniklerinin uygulanması ve reçete edilmesi hedeflenmiştir. Çalışmada moleküler gastronomi tekniklerinden tütsüleme, sous-vide ve küreleme teknikleri kullanılmıştır. Tütsüleme işlemi için kaküle, yıldız anason ve kadife çiçeği kullanılmıştır. Her bir aromatik bitki ile ayrı ayrı tütsülenen balıkların mikrobiyolojik stabilitesinin sağlanması ve gerekli aroma bileşenlerinin oluşumu amacıyla 60⁰ C de 30 dakika boyunca sous-vide tekniği ile pişirilmiştir. Sous-wide tekniği ile pişirilen balıklar yöresel bazı bitkiler ile servis edilmiştir. Balıkların servisinde yine bir moleküler teknik olan küreleme tekniği tercih edilerek, madımak, yemlik ve pezik havyarı kullanılmıştır. Bu şekilde hazırlanan tabaklar 20 panelist tarafından değerlendirilmiş ve sonuçlar istatistiki açıdan incelenmiştir. Çalışma kapsamında yapılan anketler ve değerlendirmeler ışığında yerel balık türlerinin de modern tekniklerle pişirilebileceği ve kabul edilebilir seviyelerde ürün ortaya çıkabileceği kanısına varılmıştır.
The Effect of the Restaurant Atmosphere on the Intention to Revisit: The Mediating Role of Food Neophobia
Authors: ÇANAKÇI Tuncay
Published: July 2023

The main purpose of this study is to examine the mediating role of food neophobia in the effect of restaurant atmosphere on the intention to revisit. With this purpose, the present study contributes to the literature by examining the mediator variable of food neophobia, in addition to the restaurant atmosphere and intention to revisit variables. In the study, data were collected from customers who visited five restaurants in the Kars city center and its districts, and structural equivalence modelling was used to analyze the data. According to the structural equivalence modeling path analysis, it was revealed that there is a positive and significant relationship between customers' perception of restaurant atmosphere and their intention to revisit, and there is an opposite and significant relationship between food neophobia and the restaurant atmosphere perception. On the other hand, it was observed that there was an opposite and significant relationship between food neophobia and the intention to revisit. When food neophobia was added as a mediator variable in the effect of restaurant atmosphere perception, which is the main subject of the study, on the intention to revisit, this effect was also found to be significant.
Üniversite Öğrencilerinin Turizm Bölümü Tercihlerinin Demografik Özelliklerine Göre Değerlendirilmesi ve Yaşam Doyumları İlişkisi: Ön lisans ve Lisans Turizm Eğitimi Alan Öğrenciler Üzerine Bir Çalışma: Fethiye Örneği (Department Choice Among the Factors Predicting the Life Satisfaction of University Students: A Study on Associate and Bachelor Tourism Program Students)
Authors: ÖZEN Gizem , ERGÜN Emre
Published: July 2023

Turizm bölümünde öğrenim gören öğrencilerin bölüm tercihlerinde etkili olan faktörlerin belirlenmesi, faktörlerin yaşam doyumlarına etkilerinin incelenmesi ile yaş, cinsiyet ve eğitim düzeylerine göre farklılık gösterip göstermediğinin ortaya çıkarılması araştırmanın amacını oluşturmaktadır. Bu amaçla ön lisans ve lisans eğitimi alan 224 öğrenciden basit tesadüfi örnekleme tekniği ile veriler toplanmıştır. Verilerin analizinde SPSS 22.0 programı kullanılmıştır. Faktör analizi sonucu öğrencilerin bölüm tercihini oluşturan ifadeler dört boyuta ve yaşam doyumunu oluşturan ifadeler bir boyuta indirgenmiştir. Öğrencilerin turizm bölümü seçimlerinde yaşlarına, cinsiyetlerine ve aldıkları eğitim düzeyine göre istatistiksel olarak anlamlı farklılıklara rastlanmıştır. Öğrencilerin turizm seçme boyutlarından alanın çekiciliği ve kendilerini bu alanda gerçekleştirebileceklerine olan inançlarının yaşam doyumlarına pozitif etki ettiği ortaya çıkarılmıştır.
Workload, Life Satisfaction and Intention to Leave in Hotel Businesses
Authors: YIKILMAZ İbrahim , SÜRÜCÜ Lütfi , GÜLERYÜZ İlkay
Published: July 2023

The aim of this study is to investigate the impact of life satisfaction and workload levels on the intention to leave among personnel working in accommodation establishments. The sample includes 225 employees working in Istanbul hotels that have a tourism management certificate. The study's results suggest that workload has a positive effect on turnover intention, while life satisfaction has a negative effect. Additionally, life satisfaction can mediate the interaction between workload and intention to leave. The study's results suggest that increasing employee life satisfaction levels can help reduce negative workplace experiences caused by workload and intention to leave. These negative experiences are a significant problem that can reduce productivity and customer satisfaction in accommodation businesses. The study expands on the literature on workload and intention to leave by empirically examining the role of life satisfaction in the field. Furthermore, the study offers important suggestions for effective and sustainable management practices in hotel and accommodation businesses.
Çoklu Görev ve Kariyer Uyum Yeteneklerinin Pişirme Yetkinlikleri Üzerindeki Etkisi: Aşçılık Eğitimi Alan Öğrenciler Üzerine Bir Araştırma (The Effect of Multitasking and Career Adaptability on Cooking Skills: A Study on Culinary Students)
Authors: PALA Kenan , İLHAN İbrahim
Published: July 2023

Aşçılık eğitimi alan ön lisans ve lisans öğrencilerinin temel mutfak beceri ve yetilerini ifade eden pişirme yetkinliklerine çoklu görev ve kariyer uyum yeteneklerinin etkisinin araştırılması bu çalışmanın temel amacını oluşturmaktadır. Bu doğrultuda ilgili literatürde daha önce yapılmış olan çalışmalarda güvenirliliği ve geçerliliği test edilmiş ölçekler derlenerek anket formu oluşturulmuştur. Oluşturulan anket formu basit tesadüfî örnekleme yöntemi kullanılarak mevcut eğitim-öğretim yılında aktif olarak yükseköğretim kurumlarında aşçılık eğitimi alan 482 ön lisans ve lisans öğrencisine online olarak uygulanmıştır. Hipotezler, Kısmi En Küçük Kareler-Yapısal Eşitlik Modellemesi (KEKK-YEM) ile test edilmiştir. Hem ölçüm (dış) model hem de yapısal (iç) model kullanılarak veriler iki aşamada incelenmiştir. Gerçekleştirilen analizler sonucunda elde edilen bulgulara göre, çoklu görevin ve kariyer uyum yeteneği olarak kaygının pişirme yetkinlikleri üzerinde pozitif ve anlamlı bir etkisinin olduğu tespit edilmiştir. Kariyer uyum yetenekleri olarak kontrol, merak ve güven düzeylerinin öğrencilerin pişirme yetkinlikleri üzerinde etkisi saptanamamıştır.
Vizyoner Liderlik, Örgütsel Bağlılık ve İş Performansı İlişkisi: Otel Çalışanları Üzerine Bir Araştırma (The Relationship between Visionary Leadership, Organizational Commitment and Job Performance: A Research on Hotel Employees)
Authors: SÖKMEN Alev , IŞIK YAVANOĞLU Şennur
Published: July 2023

Bu çalışmada öncelikle vizyoner liderlik, örgütsel bağlılık ve iş performansı değişkenleri arasındaki ilişkileri ortaya koymak amaçlanmıştır. Araştırma verileri, bir otel işletmesinde görev yapan 328 çalışandan 2022 yılı Ekim-Kasım döneminde toplanmıştır. Çalışmada elde edilen bulgulardan hareketle yapılan korelasyon analizi sonucunda vizyoner liderlik, örgütsel bağlılık ve iş performansı arasında pozitif yönde anlamlı bir ilişki bulunduğu tespit edilmiştir. Regresyon analizi sonuçlarına göre ise vizyoner liderliğin örgütsel bağlılık ve iş performansı üzerinde anlamlı bir etkisinin olduğunu ve örgütsel bağlılığın da iş performansı üzerinde anlamlı bir etkisinin olduğu göstermiştir. Buna göre otel çalışanlarının vizyoner liderlik algılarının artması durumunda örgütsel bağlılık ve iş performansı düzeylerinin de artacağı gözlenmektedir. Öte yandan elde edilen araştırma bulguları, incelenen otel işletmesinde vizyoner liderliğin iş performansı üzerindeki etkisinde örgütsel bağlılığın kısmi aracılık etkisinin olduğunu da göstermektedir.
Gastronomi Çalışmalarının Türkiye deki Bilimsel Evi Neresi Kahve Üzerine Gerçekleştirilen Araştırmalardan Hareketle Disipliner Yapıya Yönelik Bir İnceleme (Where is the Scientific Home of Gastronomy Studies in Turkey A Study on the Disciplinary Structure Based on Research on Coffee)
Authors: ŞİMŞEK Neslihan , GÜLER Ozan , HASEKİ Murat İsmet
Published: July 2023

Bu araştırmanın amacı, kahve konusunu odak noktasına almış yerli alanyazındaki Türkçe makale ve tezlerden hareketle, gastronomi alanının disipliner yapısını araştırmaktır. Bu amaçtan hareketle sistematik derleme kıstaslarına göre kahve konulu tez ve makaleler taranmış ve araştırma sorularına göre incelenmiştir. Bu kapsamda 18.01.2023 tarihinde “kahve” anahtar kelimesi kullanılarak filtrelenen makale ve tezlerin başlık ve özetleri incelenmiş, 87 makale ve 226 tez araştırmaya dâhil edilmiştir. Kahve konulu yayınlar disipliner farklılığı açısından incelendiğinde, hem lisansüstü tezler hem de makaleler açısından multidisipliner alanın çok baskın olduğu görülmektedir. Multidisipliner araştırmaların arkasından pazarlama, turizm işletmeciliği ve işletme gibi interdisipliner araştırmaların yoğun olduğu görülmektedir. Kahve temalı makaleler ve gastronomi anabilim dalı altında hazırlanan tezler incelendiğinde tüketici tutum ve davranışının en fazla odaklanılan konu olduğu fark edilmiştir. Buradan hareketle, gastronominin kendisini açıklama hususunda pazarlama alanından önemli oranda beslendiği görülmektedir. Sonuç olarak kahve konusuna yönelik multidisipliner ve interdisipliner akademik ilginin, gastronomi araştırmalarının ana yapısındaki çeşitliliği çok iyi bir şekilde yansıttığı söylenebilir. Bu sonuçtan hareketle, gastronominin kendi başına bir sosyal bilim disiplini olabilmesi için gastronomi alanının sınırlarını belirleyici nitelikli ve özgün araştırmalar yapılması gerektiği ileri sürülebilir.
SÜRDÜRÜLEBİLİRLİK KÜLTÜRÜ VE SİVİL TOPLUM KURULUŞLARI: İSTANBUL’DA ÇEVRE KONUSUNDA FAALİYET GÖSTEREN DERNEKLER
Authors: KONUK KANDEMİR Nebiye , HABİP Elif
Published: July 2023

Toplumsal yapının tüm unsurlarını etkileyen kaynakları etkin, verimli ve gelecek nesillere aktarılabilir şekilde kullanılmasını ifade eden sürdürülebilirlik, insan-doğa ilişkisi dengesinin bozulmasıyla farklı açılardan tartışılan bir kavram olmaya başlamıştır. Bu çalışmada ise, sürdürülebilirlik kültürü ve bunun inşasında sivil toplum kuruluşlarının rolünü ortaya koymak amaçlanmıştır. Bu çerçevede Sivil Toplumla İlişkiler Genel Müdürlüğü bünyesinde kayıtlı olan çevre dernekleri araştırmanın örneklemi olarak ele alınmıştır. Web sitesi bulunan derneklerin amaçları Birleşmiş Milletler Sürdürülebilir Kalkınma Hedefleri (17 SKH) doğrultusunda değerlendirilmiştir. Bu derneklerin Sürdürülebilir Kalkınma Hedeflerinden yeterince istifade etmediği içerik analizi ile ortaya konulmuştur. Derneklerin amaçları doğrultusunda en çok ortaya çıkan sürdürülebilir Kalkınma Hedefi “13-İklim Eylemi”dir. Elde edilen veriler ışığında bu çalışmada derneklere ve yapılacak yeni araştırmalara öneriler sunulmuştur.
Portraying Patron-client in Fishermen Work Relationships: A Phenomenon from Bengkulu, Indonesia
Authors: Adisel Adisel , Suryati Suryati , Riswanto Riswanto
Published: July 2023

The working pattern in traditional society still becomes an exciting topic to investigate as they portray how society makes their living. The research aims at investigating the relationship between employer and employee in fishing management in Kelurahan Pasar Bengkulu, Bengkulu Province, Indonesia. The study employed a phenomenology-based qualitative approach, with participants chosen using a purposive sampling technique. Data were gathered through observation, interviews, and documentation. The collected data were analyzed by reducing, describing, and verifying data. The standards of credibility, transferability, dependability, and confirmability are confirmed to validate the data. The findings signified that:1) the patron-client symbolizes exploitation in which most business is dominated by the middlemen, while the fishermen only play a role as the executors during the fishing process. Additionally, the patron-client relationship represents an imbalance of fishery profit sharing; 2) such a relationship does contribute to fishermen’s structural and cultural poverty. The cooperation between labor associations and governance active role supported by financial aid from related parties is highly recommended to promote fishermen’s wealth.
Global Forestry Data for the Economic Modeling of Land Use
Authors: Sohngen Brent , Tennity Colleen , Hnytka Marc , Meeusen Karl
Published: July 2023

*Chapter 3 of the forthcoming book "Economic Analysis of Land Use in Global Climate Change Policy," edited by Thomas W. Hertel, Steven Rose, and Richard S.J. Tol
Modeling Land-use Related Greenhouse Gas Sources and Sinks and their Mitigation Potential
Authors: Hertel Thomas , Lee Huey-Lin , Rose Steven , Sohngen Brent
Published: July 2023

*Chapter 6 of the forthcoming book "Economic Analysis of Land Use in Global Climate Change Policy," edited by Thomas W. Hertel, Steven Rose, and Richard S.J. Tol
Implications of the Biofuels Boom for the Global Livestock Industry: A Computable General Equilibrium Analysis
Authors: Taheripour Farzad , Hertel Thomas , Tyner Wally
Published: July 2023

The past decade has seen rapid growth in the global biofuels sector – particularly in the US and the EU. This has had important implications for the global livestock industry – both by raising the cost of feed grains and oilseeds and by forcing onto the market a large supply of biofuel by-products, many of which end up in livestock feed rations. This paper systematically investigates the impact of an expanding biofuels industry on the mix and location of global livestock production. Our results suggest that the impacts on specific livestock sectors in individual countries are quite varied. We estimate that growth in the US and EU biofuels industries actually results in larger absolute reductions in livestock production overseas, as opposed to in the biofuel producing regions themselves. This is due to the relatively greater transmission of grains prices into the overseas markets, as compared to the transmission of byproduct prices. We also find that the non-ruminant industry curtails its production more than other livestock industries, because it is less able to take advantage of low cost biofuel byproducts in its feed rations. Implementing biofuel mandates in the US and EU increases cropland area within the biofuel and non-biofuel producer regions. A large portion of this increase will be obtained from reduced grazing lands. The biofuel producing regions are expected to reduce their coarse grains exports and increase imports of oilseeds and vegetable oils, while they increase their exports of processed feed materials. Though biofuel mandates have important consequences for the livestock industry, they do not severely curtail these industries. This is largely due to the important role of byproducts in substituting for higher priced feedstuffs.
The Importance of Timing in the U.S. response to Undocumented Immigrants: A Recursive Dynamic Approach
Authors: Aguiar Angel , Walmsley Terrie
Published: July 2023

In an attempt to control the flow of undocumented immigrants, successive US governments have considered everything from large scale deportation, amnesties, expanding visa programs, to fining firms who hire illegal workers. Using a comparative static model, Aguiar and Walmsley (2013), find that amnesties have a positive impact on the US economy. However such policies are one-time changes in the labor force, whose benefits diminish over time, and which are unlikely to stem the flow of undocumented workers or fulfill the demands of U.S. firms for cheap foreign labor. In this paper we use a global dynamic model to investigate the long run implications of three alternative policy scenarios: 1) a one-time amnesty for undocumented workers living in the US; 2) a permanent increase in the number of foreign worker visas; and 3) enhanced border security. We find that an amnesty is much less effective than a permanent increase in visas at promoting growth in the U.S., while enhanced border control by the U.S. is beneficial for Mexico in terms real GDP. Key words: Global Dynamic General Equilibrium Model, USA Migration Policy, Permanent, One-off temporary policy changes, undocumented migrants.
Bursting the Bubble: A Long Run Perspective on Crop Commodity Prices
Authors: Baldos Uris Lantz , Hertel Thomas
Published: July 2023

Contrary to the opinions expressed by many commentators, the recent price spike in agricultural commodities is a transitory phenomenon. Using projections from SIMPLE – a global model of the farm and food system – we argue that, in the long run, food prices will most likely resume their historical downward trend. We begin with an evaluation of the historical period 1961 to 2006 wherein the growth in agricultural productivity outpaced that of global crop demand, the latter being fueled by rising population and incomes. As a consequence, we observed a historical decline in global crop prices, which the SIMPLE model faithfully reproduces. Moving forward to 2051, we establish a set of projections in global crop prices given expected developments in population, incomes, agricultural productivity and biofuel use. We project that global crop prices will continue their long run decline in the coming decades, albeit at a slower pace. However, we recognize that, under some circumstances, global crop prices could still increase by mid-century. To formally assess the likelihood of future price changes, we conduct Monte Carlo simulations given distributions in the growth rates of both drivers and economic responses. Results show that 72% of the realizations produce price declines from 2006 to 2051. Keywords: crop commodity prices, long run projections, population growth, income growth, biofuels, crop productivity JEL: Q11, Q12, Q18
Impact of surficial factors on groundwater quality for irrigation using spatial techniques: emerging evidence from the northeast region of Ghana
Authors: Kpiebaya Prosper , Shaibu Abdul-Ganiyu , Yahans Amuah Ebenezer Ebo , Kazapoe Raymond Webrah , Salifu Eliasu , Dekongmen Benjamin Wullobayi
Published: July 2023

The need for quality water in Africa for agriculture cannot be overemphasized amidst the current global water crises. The focus of this study sought to evaluate the quality of groundwater for irrigation purposes while unearthing the emerging challenges in the study area. In total, 202 groundwater samples were collected, and several parameters were tested. The study employed QGIS and multi-criteria decision analysis to examine zones of suitable groundwater quality for agriculture. Findings from the study indicate that the primary water types were Na–HCO3 and Ca–HCO3. The overall accuracy (OV) of the land use land cover (LULC) map using the Random Forest (RF) algorithm was 94.5%. The analysis revealed that SpH influences GpH at p = 0.02891 (p < 0.05) and SOM and SOC influence GNO3 at p = 0.044 (p < 0.05). The overlay analysis spatially classified the groundwater in the study area into three categories of suitability with ariel coverage showing areas of good quality (1,534.34 km2), moderate quality (1,933.35 km2), and poor quality (1,815.21 km2). The results from this study uncovered that 72.33% of the samples were within the desirable limits and it can be concluded that the quality of groundwater in the area is acceptable for irrigation.
Registrando vulnerabilidades
Authors: Sarricolea Torres Juan Miguel
Published: July 2023

El objetivo de este artículo es analizar la manera en que fueron registradas por la prensa chihuahuense, en específico por El Heraldo de Chihuahua, las vulnerabilidades de los migrantes que llegaron a la ciudad, concentrándome en el caso de los estafadores de braceros. A través de la revisión hemerográfica y partiendo de un concepto de vulnerabilidad, se muestra que la prensa registró la frecuencia y la operatividad de esta práctica durante el proceso de contratación y las representaciones que se tuvieron de los estafadores y los migrantes. Una limitación del estudio es que no fue posible consultar otros periódicos, ya que no se cuenta con los correspondientes a todos los años que duró el Programa Bracero. El valor de esta investigación reside en el tipo de fuente consultada porque permite observar el lugar que ocupó la prensa en el seguimiento de los casos y en su papel como generadora de opinión pública. Se concluye que los aspirantes a braceros fueron vulnerados por su desigual posición social y económica y en el proceso de contratación, pero también se deduce que, al saberse estafados, emplearon mecanismos de agencia política para hacer frente a los estafadores.
Using communicative games to improve speaking in English as a second language
Authors: Obando-Mejía Isamar Gissela , Reyes-Avila Roxana Margarita , Bailón-Intriago Fernanda Carolina , Reyes-Avila Jesús Orley
Published: July 2023

This study aimed to examine whether the use of communicative games can improve the students’ speaking ability in the learning process and how it influences them. In doing so, the participants were fifty-eight students (23 females and 35 males) between 16 and 18 years of twelfth grade at a public rural school in Manabí. They had an English beginner's level. Then they were divided into two equal experimental and control groups. This study used a descriptive quantitative method whereas pre-test and post-test were administrated to collect data. The experimental group was taught speaking using two communicative games “guess who” and “gossip”, whereas the control group used conventional classes. Analyzing the data through the independent sample revealed the effectiveness of games application, the experimental group outperformed the control group in the four speaking components. Furthermore, students had a positive attitude toward utilization of communicative games.
Myocardial infarction as a mask for catecholamine-induced cardiomyopathy against the background of pheochromocytoma
Authors: Ligay N. A. , Lankina M. S. , Bagaeva I. A. , Khripun A. V. , Chesnikova A. I.
Published: July 2023

Pheochromocytoma (PC) is a tumor of chromaffin cells of the sympathetic-adrenal system that produces a large amount of catecholamines (adrenaline, norepinephrine, dopamine). There are no reliable data in the literature on the frequency of cardiac manifestations of pheochromocytoma, which is associated with the rarity of this pathology. This case demonstrates the development of catecholamine-induced cardiomyopathy, proceeding under the guise of a heart attack, as the primary manifestation of pheochromocytoma. The patient was referred with a diagnosis of «Ischemic heart disease, myocardial infarction» to perform coronary angiography, according to the result of the study, no pathology of the coronary arteries was detected. In the process of additional examination, a pheochromocytoma of the left adrenal gland was revealed. The initial changes in the electrocardiogram, echocardiographic examination, and laboratory parameters regressed, which confirmed the development of cardiomyopathy that developed against the background of pheochromocytoma. Currently, there is an increasing amount of information about non-ischemic myocardial damage in patients with pheochromocytoma. These changes in the form of clinical manifestations (pain behind the sternum, shortness of breath, various types of arrhythmias) as well as non-specific changes according to ECG data, disturbances of local kinetics with a decrease in global myocardial contractility without stenotic damage to the coronary artery were called catecholamine-induced cardiomyopathy.
Patients with coronary heart disease and chronic kidney disease - the possibility of applying cell adhesion molecule as a predictor of disease progression
Authors: Samakaev A. S. , Glova S. E. , Zimoveyskaya E. E. , Khaisheva L. A. , Shlyk S. V.
Published: July 2023

Objective: to study the level of type 1 vascular endothelial adhesion molecule in patients with coronary heart disease depending  on the stage of chronic kidney disease. Material and methods: the study included 115 patients, mean age was 67.56±12.42 years (63 men, 52 women) with ischemic heart disease (CAD), stable angina (tension), functional class 1–3, chronic kidney disease (CKD) C1–C3. The level of the vascular endothelial adhesion molecule type 1 (VCAM 1) was assessed using the enzyme immunoassay kit for the quantitative determination of human VCAM 1 ThermoFisher scientific. Results: in patients with CAD and CKD, the level of serum VCAM 1 progressively increases as angina pectoris worsens and can be regarded as an early marker of CAD progression. The level of VCAM 1 does not depend on the stage of CKD. When studying the correlation relationships between the level of serum VCAM 1 and clinical and laboratory data, it was found that there is a correlation relationship between VCAM 1 and the level of SBP and DBP. Conclusion: in patients with CAD and CKD, it is advisable to use the determination of the level of VCAM 1 to identify patients with a high risk of cardiovascular complications.
Phenotype of bronchial asthma with obesity in combination with chronic coronary heart disease
Authors: Noskova E. V. , Simonova Zh. G. , Balandina Yu. A.
Published: July 2023

Objective: to study the clinical characteristics of patients with the phenotype of obese brochial asthma in combination with chronic coronary heart disease. Material and methods: in an open-label  clinical trial, two groups of patients with chronic coronary heart disease (CHD) and bronchial asthma (BA) were formed. Patients of group I (n=43) had obesity as a concomitant disease. Group II (n=50) were non-obese patients. All patients underwent a general clinical examination. The results of Holter’s daily monitoring of the electrocardiogram (HMECG), duplex scanning of the brachiocephalic arteries (BCA DS), transthoracic echocardiography (EchoCG), coronaroangiography (CAG), and spirography  were evaluated. The results of biochemical blood testing were also evaluated. Results: for patients of group I, the main complaints were shortness of breath (84% vs 62%, p=0,036) and cough (65% vs 40%, p=0,027) compared with patients of the control group. According to the results of echo-CG in this group, signs of overload of the left heart were revealed. The LV EDV score was more significant than in the control group (p=0,034). The thickness of IVS is also more significant in patients of group I (p=0,022). Ultrasound of the common carotid and internal carotid arteries revealed atherosclerotic plaques in 53% of patients of group I vs 30% (p=0,037) of the control group. According to CAG, the prevalence of RCA stenosis was more significant in patients of group I (56% vs 24%, p=0,003). In patients of group I, spirometry showed a more pronounced decrease in OFV1 (64,1±6,7 vs 66,9±7,1, p=0,042). Conclusion: the adipose BA phenotype combined with CHD is characterized by more frequent cough complaints as the equivalent of choking  in bronchobstructive  syndrome. Also, patients are more likely to note shortness of breath as the equivalent of angina pain and, possibly, the manifestation of respiratory and heart failure. These clinical features of the phenotype are reflected in the results of instrumental examination methods: pronounced atherosclerotic vascular damage, signs of overload of the left heart, a more significant decrease in the FEV1 rate.
Predicting outcomes of dual antihypertensive therapy
Authors: Okorokova T. O. , Krjuchkova O. N.
Published: July 2023

Objective:to establish predictors of failure of dual antihypertensive therapy in patients with arterial hypertension (AH) of high and very high cardiovascular risk, to create a predicting model for the negative outcome of dual antihypertensive therapy. Materials and methods: The study included 88 patients with uncontrolled hypertension who did not receive basic antihypertensive therapy, mean age 58.0±1.52 years. The examination was carried out on the basis of the current regulatory documents regulating the examination at the stationary stage. Additionally, the level of highly sensitive C-reactive protein and blood uric acid was determined. 24-hour blood pressure monitoring (ABPM) and electrocardiogram (ECG), respiratory polygraphy of sleep, and computerized  capillaroscopy  were performed. The search for predictors and the creation of a predictive model were carried out using  the binary logistic  regression method. Results: the effectiveness of dual drug therapy was 33.0%. Prognostic markers associated with a negative outcome of treatment were identified: interventricular septal thickness (IVS) (OR 3.44; p=0.009), linear density of the capillary network (OR 4.65, p<0.001), area density of the capillary network (OR 3, 98; p<0.001); remodeling  coefficient (OR 8.40; p=0.003), mean nighttime systolic blood pressure (SBP) (OR 1.94; p=0.014), mean daily SBP (OR 2.86; p=0.014), SDNNi (OR 2 .86; p=0.007). The final model included the IVS, areal density of the capillary network, and the average daily SBP. Model characteristics: regression coefficient 25.74; p<0.001; p Wald 0.049; OR 9.1 (95% CI 3.12; 26.82). The sensitivity of the method was 83.1%, the specificity was 69.0%. The area under the ROC curve was 0.805±0.05 (95% CI 0.707; 0.882). The cut-off point corresponded to the calculated probability value of 0.599. Conclusions: the study demonstrated the low efficacy of dual antihypertensive therapy. Given the lack of approved algorithms for predicting outcomes of drug treatment in patients with uncontrolled hypertension, the developed model is of clinical interest and may be useful in achieving better BP control. To improve the quality of the model in order to increase the sensitivity and specificity of the method, further study on larger samples is required.
Some immune mechanisms of inflammation in bronchial asthma combined with type 2 diabetes mellitus
Authors: Skiba T. A.
Published: July 2023

Objective: to study the immune mechanisms of inflammation of the patients with BA in association with type 2 diabetes mellitus (DM). Materials and methods: the study involved 215 patients with persistent BA of moderate severity at the age of (28.6±2.4) years, including  88 men (40.9%), 127 women (59.1%). Among the examined patients with BA there were 64 — group I, persons with BA in association with type 2 diabetes — 151 (group II), in whom, along with routine laboratory and instrumental methods, cellular immunity, IgE and lymphocytic autoantibodies were determined. Results: patients with BA in combination with type 2 diabetes more often have an uncontrolled course of the disease with a complication in the form of grade II respiratory failure. In patients with BA, as well as with BA in combination with type 2 diabetes, the formation of secondary immunodeficiency due to the cellular link was noted. The combination of BA and type 2 diabetes is characterized by the most pronounced negative changes in cellular immunity among all examined patients. In BA in combination with type 2 diabetes, a decrease in the concentration of IgE was noted along with an increase in the number of lymphocytic autontibodies. Conclusion: patients with BA in combination with type 2 diabetes have a more severe course of BA and the addition of a more destructive autoimmune to allergic inflammation, which increases the risk of complications of both diseases.
Anki Tagger: A Generative AI Tool for Aligning Third-Party Resources to Preclinical Curriculum (Preprint)
Authors: Pendergrast Tricia , Chalmers Zachary
Published: July 2023

UNSTRUCTURED

Using large language models, we developed a method to efficiently query existing flashcard libraries and select those most relevant to an individual's medical school curricula.
A Patient-Driven Mobile Health Innovation in Cystic Fibrosis Care: Comparative Cross-Case Study (Preprint)
Authors: Mazzocato Pamela , Luckhaus Jamie Linnea , Malmqvist Castillo Moa , Burnett Johan , Hager Andreas , Oates Gabriela , Wannheden Carolina , Savage Carl
Published: July 2023

BACKGROUND

Patient-driven innovation in health care is an emerging phenomenon with benefits for patients with chronic conditions, such as cystic fibrosis (CF). However, previous research has not examined what may facilitate or hinder the implementation of such innovations from the provider perspective.

OBJECTIVE

The aim of this study was to explain variations in the adoption of a patient-driven innovation among CF clinics.

METHODS

A comparative multiple-case study was conducted on the adoption of a patient-controlled app to support self-management and collaboration with health care professionals (HCPs). Data collection and analysis were guided by the nonadoption, abandonment, spread, scale-up, and sustainability and complexity assessment tool (NASSS-CAT) framework. Data included user activity levels of patients and qualitative interviews with staff at 9 clinics (n=8, 88.9%, in Sweden; n=1, 11.1%, in the United States). We calculated the maximum and mean percentage of active users at each clinic and performed statistical process control (SPC) analysis to explore how the user activity level changed over time. Qualitative data were subjected to content analysis and complexity analysis and used to generate process maps. All data were then triangulated in a cross-case analysis.

RESULTS

We found no evidence of nonadoption or clear abandonment of the app. Distinct patterns of innovation adoption were discernable based on the maximum end-user activity for each clinic, which we labeled as low (16%-23%), middle (25%-47%), or high (58%-95%) adoption. SPC charts illustrated that the introduction of new app features and research-related activity had a positive influence on user activity levels. Variation in adoption was associated with providers’ perceptions of care process complexity. A higher perceived complexity of the value proposition, adopter system, and organization was associated with lower adoption. In clinics that adopted the innovation early or those that relied on champions, user activity tended to plateau or decline, suggesting a negative impact on sustainability.

CONCLUSIONS

For patient-driven innovations to be adopted and sustained in health care, understanding patient-provider interdependency and providers’ perspectives on what generates value is essential.
Antara Ie dan Dadia: Perbandingan Nilai Budaya dalam Upacara Soushiki pada Masyarakat Jepang dan Upacara Ngaben pada Masyarakat Bali
Authors: Ariani Putu Krisna , Wibowo Robi
Published: July 2023

Penelitian ini membahas mengenai perbandingan pada upacara kematian soushiki yang dilakukan oleh masyarakat Jepang dan upacara ngaben yang dilakukan oleh masyarakat Hindu Bali. Tujuan dari penelitian ini adalah untuk mengetahui rangkaian prosesi serta menjabarkan perbedaan dan persamaan dari kedua upacara tersebut, dilihat dari nilai budaya yang terkandung di dalamnya, yakni ie dan dadia. Penelitian ini menggunakan metode deskriptif kualitatif dengan data yang diperoleh dari buku, jurnal, serta data kepustakaan yang menunjang penelitian. Hasil dari penelitian ini menunjukkan bahwa upacara soushiki dan upacara ngaben masing-masing memiliki tiga rangkaian prosesi utama, meliputi persiapan upacara, pelaksanaan upacara, dan kegiatan setelah upacara. Selain itu, upacara soushiki dan ngaben memiliki persamaan dan perbedaan yang dapat dilihat dari rangkaian prosesi serta sistem kekerabatan ie dan dadia yang melandasi berlangsungnya upacara soushiki dan ngaben. Pada intinya, peneliti menemukan tiga poin utama dalam perbandingan nilai budaya pada upacara soushiki dan ngaben. Pertama, pelaksanaan upacara soushiki dan ngaben memiliki kaitan yang erat dengan kepercayaan, yaitu Buddha pada upacara soushiki dan Hindu pada upacara ngaben. Kedua, pelaksanaan soushiki dan ngaben sebagai upacara kematian memiliki fungsi yang serupa, yakni mengembalikan arwah ke tempat asalnya. Ketiga, pelaksanaan upacara soushiki dan ngaben dilandasi oleh ie dan dadia sebagai suatu konsep yang menyangkut hubungan kekerabatan pada masyarakat, khususnya masyarakat Jepang dan Bali.
Queens in Folklores as Representation of Indonesian Feminism
Authors: Wiyatmi Wiyatmi
Published: July 2023

The view that the patriarchic system has dominated human life is untrue. Evidence has been found that, in the history of human civilization, women have been raised to the royal throne and ruled a kingdom. The existence of a queen has also been found in folklore in Indonesia. Using the qualitative research design with the perspectives of feminist literary criticism, the present study analyzes four folklore titles with a queen as the main character, such as: (1) The Legend of the Hermitage of Queen Kalinyamat, (2) Queen Kencanawungu, (3) Madam Undang Beautiful Queen from Kupang Island, and (4) The Legend of Princess Rengganis. Findings show no gender bias in the transfer of the royal inheritance or in choosing the successor of the royal throne in some kingdoms of regions in Indonesia. The crowning of a new ruler is more based on kinship and leadership qualities. This research also shows that before the emergence and development of feminism in the West, it has been existed in the archipelago, which can be called Indonesian feminism, i.e, feminism that gave women rights and voices not only in the domestic sphere but also in the public sphere, as a queen whose power was recognized.
A Study on the Impact of Urban Digitalization on the Urban-rural Income Gap
Authors: Zheng Jin , Tan Zhengwei , Dou Mengmeng , Mao Danni
Published: July 2023

The empirical research topic for this paper is a panel dataset of 31 provinces and urban areas from my country from 2011 to 2020. On the one hand, it gauges the level of regional digital economic development. On the other side, we’ll talk about the structural impact of the level of digitalization on the urban-rural income difference and further debate whether the digital economy helps close or widen this gap. The findings show that the degree of digitization has a significant impact on reducing the income gap between urban and rural areas, while an increase in the Internet coverage index helps do so. However, the overall impact makes the digital economy unfavorable to reducing the income gap between urban and rural areas.
The Future of Cybersecurity and Its Potential Threats
Authors: Ramakrishnan R
Published: July 2023

Abstract: The future of cybersecurity brings forth a range of advancements and threats in the ever-evolving digital landscape. This article provides an overview of the potential threats that individuals and organizations may face in the coming years. It explores vulnerabilities in the Internet of Things (IoT), the exploitation of artificial intelligence (AI) and machine learning (ML), the risks posed by quantum computing, supply chain attacks, cloud security challenges, and social engineering and phishing attacks. By understanding these threats, individuals and organizations can develop proactive strategies to enhance cybersecurity measures and protect their digital assets. Collaboration, technological innovation, and user awareness are key to navigating the future of cybersecurity successfully and ensuring the integrity of our digital infrastructure.