bluuebunny/crossref_metadata_2025 huggingface dataset:
Relevance of posterior malleolar fracture fixation to ankle syndesmotic reduction, a comparative study
Authors: Elshahhat Amr , Youssef Khaled , Elkasaby Mohammed , Gaarour Osama Samir
Published: October 2022

Background: Appropriate distal tibiofibular syndesmotic reduction is crucial to restore ankle stability, guard against future arthrosis with worse functional outcome. Optimal technique for syndesmotic reduction has been a matter of debate. This study aimed at radiological evaluation of syndesmotic integrity following two methods of reduction (posterior malleolar fixation and trans-syndesmotic screw fixation), additionally, correlating the posterior malleolus size to the radiological results of both techniques.

Methods: Syndesmotic integrity was compared after each technique as per translational and rotational fibular positions. Utilizing, preoperative and postoperative computed tomography scans of injured ankle, the fibular antero-posterior and Medio-lateral translation distances were measured. Additionally, the fibular rotation angle was calibrated. Incidence of inadequate reduction in each group was reported. Preoperative and postoperative radiological findings were compared and correlated to posterior malleolus size in relation to tibial articular distance.

Results: A significant difference between both techniques was noted in term of fibular rotation. In patients with PM ˂ 10% of tibial articular surface, a significant difference was obvious in postoperative AP-translational and rotational findings between both techniques. Overall malreduction incidence rate of 68.9% was reported in this study, with 84.7% rate in patients managed with SS-fixation, whilst 51.2% rate in those managed via PM-fixation.

Conclusions: Posterior malleolar fixation could limit syndesmotic malreduction risk whatsoever it’s size. Approaching CT reference values for syndesmotic reduction might benefit preoperative planning and detect intraoperative malreduction. Further future clinical studies correlating these findings to clinical outcome would be more helpful.
Determine the functional and radiological outcome of T3 proximal femur nail in the treatment of intertrochanteric fracture of femur
Authors: Paneliya Manan B. , Shetty Sunil H. , Chand Kumar Abhineet , Sharma Vidur
Published: October 2022

Background: T3 is the new generation nail used for fixation of intertrochanteric fractures. The lag screw is designed to transfer the load of the femoral head into the nail shaft by bridging the fracture line to allow fast and secure fracture healing. The load carrying thread design of the T3 lag screw provides large surface contact to the cancellous bone, this provides high resistance against cut out.

Methods: 30 subjects attending the study were operated with T3 proximal femur nail in the treatment of intertrochanteric fracture of femur. Prospective, randomised case-controlled study done over period of 1 year.

Results: Significant results were obtained while comparing the mean RUSH score and mean Harris hip score at different postoperative follow-up time intervals with good to excellent outcome and less operative time and low complications rate.

Conclusions: T3 is the new generation nail used for fixation of intertrochanteric fractures and is a dependable implant for the fixation. It has good to excellent outcomes and takes less operative time with low complication rates. The anatomical shape of the nail is universal for all indications involving the treatment of intertrochanteric fractures. The load carrying thread design of the T3 lag screw provides large surface contact to the cancellous bone, thus providing high resistance against cut out. The set screw prevents rotation of the lag screw. The T3 has a single screw passing into the neck of the femur and its Set Screw that is passed into the proximal part of the femoral nail sits into the groove of the Lag screw, thus providing rotational stability.
Functional outcome analysis of fixation of distal radius fractures using five pin technique
Authors: Sakharkar Nilesh S. , Tathe Pankaj V. , Bhurre Rohit K. , Arora Chandan
Published: October 2022

Background: One of the most frequent injuries seen in orthopaedic practise is a distal radius fracture. They account for 8-15% of all adult bone injuries. Younger and older age groups are both affected by distal radius fractures, which are bimodal in distribution and correspond to high and low energy trauma, respectively.

Methods: 25 patients with distal radius fractures who were hospitalised and subsequently underwent five pin fixations as well as those who came to the outpatient department for postoperative follow-up.

Results: We evaluated at 25 patients who had distal radius fractures prospectively. The patients' ages ranged from 22 years to 68 years old, with a mean age of 42.8 years among them at the time the fracture was first noticed. Among the patients, there were 18 men (72%) and 7 women (28%).

Conclusions: The five-pin technique treats displaced intra and extra articular fractures without significant articular and metaphyseal comminution and is minimally invasive.
Type 4 congenital proximal radio-ulnar synostosis mimicking as malunited radial neck and deformed radial head with insidious onset extension block: a case report and results after excision
Authors: Arora Chandan , Jagtap Satyajeet , Jain Prateek , Sakharkar Nilesh
Published: October 2022

Proximal radio ulnar synostosis is a rare entity presenting with restriction of supination and pronation. Among the various types, type 4 variety is even more-rare and its presentation, can pose a diagnostic challenge specially, if with history of trauma. Radiologically, it is usually overlooked as a malunited radial neck and therefore needs thorough evaluation. We presented a case of a 15-year-old male who complains of new onset extension block following trauma, with chronically restricted supination and pronation. History suggested the restriction in supination and pronation since birth, and the extension block occurring de novo. Radiographs and CT scan of the elbow revealed proximal radio-ulnar synostosis and anteriorly dislocated, mushroom-shaped radial head, misleading and mimicking like an old, neglected and malunited radial neck fracture with a deformed radial head.  The family insisted to not address the restriction of supination pronation but, asked for solution to more disabling extension block. Thus, patient was managed with open procedure, involving radial head-neck excision and removal of malformed radial head. At 1-year follow-up, the child has a well-reduced and stable elbow joint with a functional range of flexion and extension movements with restricted supination and pronation. Type 4 congenital radio ulnar synostosis not only leads to conventionally known restriction of supination pronation but also give rise to extension block de novo as presented in this case. Excision of the deformed head and neck can treat the restriction in extension, however the synostosis will require various other augmented procedures.
Primary tendon repair in a case of acute traumatic tibialis anterior with extensor hallucis longus tendon rupture in a young male-a case report
Authors: Patel Ravi , Mahajan Neetin P. , Chaudhari Kunal , Bagimani Pramod , Gund Akshay
Published: October 2022

Tibialis anterior tendon rupture is a rare entity which can be either traumatic and non-traumatic. It often presents late due to mild clinical symptoms and signs. Acute ruptures are traumatic occurring in young individuals while chronic ruptures are due to degenerative processes occurring in elderly individuals, commonly after 45 years of age. Tibia anterior along with extensor hallucis tendon is an even rarer entity, operative management of which becomes mandatory, more so in a young active individual for better outcome. We have a 31-year-old male patient, who presented to us with an acute post traumatic tibialis anterior tendon rupture of 3 days duration which was diagnosed following an initial clinical examination, an unremarkable X-ray picture, and Ultrasonography confirming the diagnosis. The patient was managed with primary repair of the tibialis anterior tendon along with Extensor hallucis tendon (which was found intra-operatively) with 2-0 ethibond sutures using a cross-linked Bunnell technique. The patient regained full ankle range of motion at 8 weeks post operative period with ankle dorsiflexion and great toe extension back to pre-injury state.As we have seen with this case, early primary repair in a case of acute rupture at tibialis anterior and extensor hallucis longus rupture with non-absorbable suture has significant improved post operative outcome in terms of return of the affected range of motion and can be practice safely in new hands with limited resources as material of suture and technique has not significant effect in post operative outcome. Acute tibialis anterior and extensor hallucis tendon rupture, non absorbable suture, ethibond, cross linked Bunnell technique.

 
Osteoarthritis: insights into pathogenesis and futuristic treatment strategies
Authors: Singh Ajay , Rai Vikramaditya , Pandey Sushmita , Chavan Manisha , Ketha Deepthi
Published: October 2022

Osteoarthritis is the most common musculoskeletal condition world over that causes significant health, economic, and societal burdens. Till date, no therapeutic approaches have been able to stop or delay the progression of osteoarthritis satisfactorily. Structural and clinical features of the disease are characterized by a high inter-patient variability. This heterogeneity is believed to be a major factor associated with the complexity of osteoarthritis and the on-going difficulty to identify a single therapy for all sub-groups. The objective of this review is to highlight recent advances in the understanding of the pathophysiology of osteoarthritis and latest biological treatments available, their limitations and to bring to notice the latest state-of-the-art on-going research on novel therapies. For this study we searched different online databases such as PubMed and Cochrane Library from inception to January 2022. We identified eligible studies on the pathophysiologic findings, prevalence, or incidence of knee osteoarthritis, available treatments, and current research for future therapies. Besides the availability of vast literature on cartilage extracellular matrix and its changes in osteoarthritis, the complicated mechanism of the disease still has missing links in the chain. Presently, biological treatments such as platelet rich plasma, bone marrow mesenchymal stem cells and autologous fragmented adipose tissue containing structural vascular fraction are commonly used. In future, gene therapy could become a potential option for treating the disease. More extensive insights into the pathophysiology of osteoarthritis will be helpful in designing therapies that can curb structural progression and promote cartilage regeneration thus providing more potent relief from painful and disabling condition associated with osteoarthritis.
Study of endocrinal profile and trichoscopic features in female pattern hair loss at tertiary care hospital
Authors: Naik Ravina R. , Shukla Pankaj
Published: October 2022

Background: Patterned hair loss is one of the commonest conditions for which both men and women seek dermatologist. Though term androgenetic alopecia is used synonymously for female pattern hair loss, role of androgens and other hormones in its causation remains controversial. Also, in literature few studies are present suggesting role of trichoscopy in female pattern hair loss. We sought to investigate role of endocrine disturbances and trichoscopic findings in female pattern hair loss as per Ludwig classification.

Methods: This was a prospective case control study. 100 cases and 100 age matched controls were enrolled in study. Laboratory investigations were done in both groups and trichoscopic examination was done in cases, at frontal and occipital scalp. The data was analyzed using t test, McNemar test and as mean, standard deviation and as percentages.

Results: The difference between the mean value of body mass index, hemoglobin, T4, prolactin, follicle stimulating hormone, testosterone and dehydroepiandrosterone were found to be statistically significant as compared to controls. On trichoscopy, hair diameter diversity was commonest findings, however focal atrichia, 2-3 hairs/hair unit, white dots, honey comb pigmentation (HCP) correlated with grade of hair loss.

Conclusions: Our study supports role of hormonal disturbances in causation of female pattern hair loss and thus we recommend doing tests in early onset and severe degrees of hair loss. Though diagnosis is mainly clinical trichoscopy could be excellent tool which is simple, non-invasive and cost-effective tool and may help to differentiate Female patterned hair loss from other condition like chronic telogen effluvium.
Dermoscopy of livedoid vasculopathy in skin of color treated successfully with colchicine: a case report
Authors: Ankad Balachandra S. , Nagur Sushila K. , Nikam Balkrishna P.
Published: October 2022

Livedoid vasculopathy (LV) is recurrent and episodic thrombotic dermatosis characterized by pain and ulcerations. It requires early diagnosis, and treatment with combination of drugs. Dermoscopy is a non-invasive technique which enables clinician to visualize subsurface structures of the skin. Here, dermoscopy of LV in skin of color which was treated with colchicine is reported.

 
Management of formocresol burn-case report
Authors: Nandkule Vrushali Raju , More Pratiksha Harishchandra , Shelke Shailee , Nandkule Rutuja Raju , Landge Yogita Uttam
Published: October 2022

Formocresol is widely used in pediatric endodontics as a pulpotomy medicament. Formocresol helps to fix soft tissues in oral cavity such as pulp. Care should be taken while using formocresol proper isolation techniques should be used during its application as an endodontic material, because of its hazardous effects on soft tissue. This article elaborates the case of chemical burns due to improper handling of formocresol during dental treatment. It demonstrates the underlying effect such as moderate pain burning sensation and patchy dark discoloration of skin and its resolution.
Current understanding of multi-country human monkeypox outbreak: a narrative review
Authors: Vas Geoffrey
Published: October 2022

Outbreaks of infectious diseases have occurred throughout history. They appear to be increasing in frequency, particularly because of the increasing emergence of viral diseases from animals. Monkeypox is a zoonotic orthopoxviral, similar to smallpox, although with lower mortality. Cases of human monkeypox are rarely seen outside of west and central Africa. The current outbreak is the first of its kind where the transmission is reported in Europe without known links to Africa. India reported the first case of monkeypox from the Southeast Asia region in the state of Kerala, on July 14, 2022. India till now (August 2022) has reported nine monkeypox cases and one death owing to the viral zoonosis infection. It causes flu-like symptoms such as fever, chills, and rash, usually mild, and most patients recover without therapy. As with most viral illnesses, the treatment's mainstay of clinical management for a typical monkeypox infection is supportive symptom management. Acting quickly and proactively, focusing on building surveillance, promptly identifying monkeypox infection, and implementing preventive measures will be vital for containing this pandemic.
Employee Entitlement: Is There A Universal Approach That We Can Use in the Organizational Settings?
Authors: Piotrowski Piotr , Besta Tomasz
Published: October 2022

Employee entitlement has been studied over the years, yet few human resources management scholars and managers expected it to be a common phenomenon, especially among younger employees. Therefore, there is a need for deeper insight into employee entitlement as it has been analyzed in different ways over the last years. Due to dynamically and rapidly changing organizational settings, employee entitlement should be considered as a context-dependent variable. Additionally, it does not have to be perceived explicitly as a negative factor, as there are certain circumstances in which employee entitlement may be beneficial for the organization. Proper understanding of it will be possible through studying the interactions between employee entitlement and other variables, such as organizational identification, identification with coworkers, organizational justice, leader-member exchange, team–member exchange, organizational citizenship behavior, and counterproductive behavior. Factors that might affect the intensity of entitlement are discussed, as well as what we know about methods that can increase or decrease it. This article indicates the gaps and inconsistencies in existing research, simultaneously trying to find solutions and ideas for the difficulties encountered.
Negotiating Capital and the EU-Japan Economic Partnership Agreement
Authors: Kimura Christopher
Published: October 2022

The 2019 European Union (EU)-Japan Economic Partnership Agreement is, so far, the EU’s largest bilateral free trade agreement. While the agreement itself is an example of the growing strength of the EU-Japan relationship, it is also an example of how two vastly different trade regimes can overcome entrenched structural and administrative styles to reach a consensus. This paper analyzes one of these barriers: negotiating capital. This concept represents the political economy of how trade negotiators utilize their legal expertise, negotiating flexibility, and limited resources to maximize free trade agreement outcomes. However, trade negotiators have differing amounts of negotiating capital, which depends on their home states’ structural and administrative constraints and how the trade negotiators define and develop their trade expertise. The EU’s and Japan’s contrasting structural and administrative approaches to trade negotiations and how trade experts define and develop their expertise lend a unique opportunity to understand how changes in negotiating capital can alter free trade agreement negotiation outcomes. Ultimately, the EU’s inclusive, quasi-federal structure and the negotiators’ need to consider the limitations on their trade mandate show how their negotiating capital is relatively limited and translates into a more integrated agreement text, i.e., provisions on public opinion. On the other hand, Japan’s top-down reformist trade regime leads to a more reactive strain of negotiating capital relying heavily on adherence to hierarchy and limited inclusiveness, resulting in agreement commitments that are generally weak and narrow. Negotiating capital is an important reality that all trade negotiators face. It is politically and strategically important for parties to understand how these various factors’ political economy impacts free-trade negotiations and outcomes.

Received: 10 May 2022Accepted: 18 July 2022
The Modernization Resolution of Vietnam’s Education System by the Francophone Road in the East-West Cultural Conflict of the Late Nineteenth Century and the Early Twentieth Century
Authors: Mậu Hùng Nguyễn
Published: October 2022

Even though the colonial authorities tried to use education as a political tool to serve their ruling purposes, the francophone education system was an important bridge between Vietnam’s traditional Confucian education and mankind’s modern one. One of the greatest achievements of the francophone education system in Vietnam was the training of a modern westernized intelligentsia different from traditional Confucian intellectuals. Although the Soviet and other socialist educational models later replaced the francophone education system, the cornerstones of all existing modern educational models of Vietnam have originated from the very first settlements of the francophone education in the Far East Country. The fundamental elements of the francophone education therefore play an important role in the integration and development of the Vietnamese education into the modern world education system. The modernization of the Vietnamese education system in the colonial period under the decisive influences of the francophone model could, to some extent, be seen as a historical resolution to modernity of Vietnam’s schools in the circumstances of the East-West dispute that nearly all Asian countries experienced in the second half of the nineteenth century and the first half of the twentieth century.

Received: 19 May 2022Accepted: 18 July 2022
Pravni vidiki digitalizacije v podjetjih
Authors: Pastirk Gal
Published: October 2022

Vsako podjetje si prizadeva postati čim uspešnejše in konkurenčnejše. V današnjih časih je te cilje nemogoče doseči, ne da bi se podjetje spoprijelo z izzivi digitalizacije. Digitalna preobrazba podjetij je tudi ena temeljnih idej EU, ki želi s tem okrepiti svoj položaj in izkoristiti sodobna znanja o digitalnih tehnologijah. Obenem pa se je ob tem neizogibno soočiti s pravnimi vprašanji, kot so nove oblike pogodbenih razmerij, varstvo osebnih podatkov in zasebnost na delovnem mestu, ki so posledice digitalne transformacije. Posamični primeri pravnega normiranja, nastalega kot posledica digitalizacije podjetniškega delovanja, so podkrepljeni s teorijo kot tudi s primeri prakse v dveh slovenskih podjetjih.
Digitalizacija epidemiološkega spremljanja bolnišničnih okužb in eZdravje
Authors: Bračič Lana , Šajt Duh Nina , Milošič Tomi
Published: October 2022

V prispevku smo pozornost namenili še enemu svetovnemu javnozdravstvenemu problemu – antibiotični rezistenci in večkratno odpornim mikroorganizmom. Antibiotiki so nujen del zdravstvene oskrbe, a jih počasi, vendar zanesljivo zmanjkuje. V zadnjih letih zdravstvena stroka poudarja pomembnost preudarne rabe antibiotikov, saj nepravilna raba le-teh vodi v razvoj večkratno odpornih bakterij, ki so pomembne povzročiteljice bolnišničnih okužb. Bolnišnične okužbe so okužbe, ki so povezane z diagnostiko in zdravstveno oskrbo v bolnišnici. So eden izmed pogostejših zapletov zdravljenja, predvsem pri pacientih v intenzivnih enotah, pacientih z urinskimi ali centralnimi katetri ter po kirurških posegih. V Sloveniji se trenutno primerov okužb/nosilstva večkratno odpornih bakterij niti pojavov ostalih bolnišničnih okužb ne prijavlja epidemiološki službi. V prispevku smo pripravili idejno zasnovo za beleženje bolnišničnih okužb, saj je njihovo spremljanje uporabno kot kazalnik kakovosti bolnišnične oskrbe in je v pomoč pri ukrepanju in preprečevanju širjenja.
Digitalno evidentiranje delovnega časa
Authors: Krajšek Luka , Bračič Lana , Dogša Matej , Šajt Duh Nina
Published: October 2022

Digitalizacija na delovnem mestu je prihodnost vsakega podjetja. Nekatera so pri tem naprednejša, spet druga z digitalizacijo nekoliko zamujajo. Vsako se torej tega neizogibnega postopka loteva v svojem tempu. A kje začeti, ko določeno delovno področje v podjetju še ni digitalizirano? Kje in kako začeti, ko pri zaposlenih zaznavamo odpor, morda celo strah pred uvedbo tovrstne novosti? V sodelovanju s podjetjem TDR Legure d.o.o. smo se lotili izziva uvedbe digitalnega evidentiranja delovnega časa. Opredelili smo rešitev, ki je najustreznejša glede na izbrane selekcijske kriterije. Poskušali smo poiskati vzroke strahu pred digitalizacijo pri zaposlenih in navesti način uvedbe, s katerim lahko podjetje poskuša ublažiti zaznani odpor in strah pri zaposlenih. S poglavjem želimo ponuditi tako tehnično kot tudi nekoliko bolj psihološko rešitev vpeljave digitalnega evidentiranja delovnega časa ne le za podjetje, s katerim smo sodelovali, ampak tudi za druga podjetja, ki se bodo znašla na podobni točki digitaliziranja.
Slovenia has built a system of local self-government within the main provisions of the European Charter on local self-government. According to the local Self-Government Act, municipalities have some competences in individual areas of development, including tourism. However, the existing system could further benefit from enhancing local autonomy – whether in policy scope or fiscal capacity. Municipalities are not stimulated to engage in proactive management of local policies and services, and although the competences of municipalities are regulated (and protected) by the Constitution, the Local Self-Government Acts and special laws, some policy areas are too loosely defined and rely heavily on the agendas of individual local governments. In this contribution, we address the question of how municipalities collect resources to develop tourism, and what are the issues in planning tourism-related investments.
Authors: Borlinič Gačnik Maja , Rančić Demir Milica
Published: October 2022

The scientific monograph on current topics of tourism development, which is intertwined with the field of health, well-being, and the role of local authorities in planning, implementing, and evaluating policies and practices related to public health issues, offers the reader a systematic theoretical review of scientific literature, as well as case studies of the topics discussed. The content is presented by numerous researchers and experts who are active in Slovenia or other countries of the former Yugoslavia. The topics address current issues in the development of tourism science. The content is multidisciplinary and interconnects various views and concepts that provide an insight into the profession for the needs of further development of the sector.
Motivations for Hosting on Airbnb: the Case of Slovenia
Authors: Kokot Katja , Turnšek Maja
Published: October 2022

The ‘platform economy’ has evolved over the years into a global phenomenon. The focus of this paper is the motivations of Slovene hosts to use the Airbnb platform. While Airbnb was originally optimistically discussed as an element of ‘the sharing economy’, it has become known as one of the key players of the ‘platform economy’, belonging to the area of the so-called capital platforms, which allow participation-based primarily based on ownership of capital. Our research amongst a sample of 103 officially registered accommodation providers in Slovenia has shown that Airbnb is the second-most used platform, on average bringing a third of income for the surveyed participants, while Booking.com brings about half of their income. Furthermore, the results show that monetary motives prevail among Slovene hosts. However, social and moral motives are also strongly expressed. These findings indicate that the perceived primary purpose of Airbnb is generating additional earnings due to a surplus of real estate capital. A higher share of income from hosting in comparison to other types of income is correlated with the expressed importance of monetary motives. In contrast, the prevalence of social motives is influenced by fear of loneliness, cultural openness, and hosts’ global prosociality.
Influence of Explainer Videos in Marketing Communication for Tourism and Health Services
Authors: Sedej Tanja , Mlaker Kač Sonja
Published: October 2022

Digital marketing has been gaining more attention in last years. Several researchers have shown that it is a very powerful tool in the field of storytelling. In the last decade tourism has changed from typical destination marketing to approaches that often use storytelling, augmented reality, the sharing economy, all-year tourism, etc. Most of these tourism offers can be best promoted via digital media. Especially when it comes to the younger generation, social and digital media are crucial for success. Our research focuses on explainer videos and their importance in marketing for the tourism sector aimed at young people. Our research was conducted with a group of Slovenian students. The results show that explainer videos have great potential in field of destination marketing, event promotion (such as for sport and cultural events) and services (such as sharing-economy systems and health services) among the student population. Our research has also shown the content and animation/images used in explainer videos are the most important elements in attracting and holding the attention of younger generation.
Tourism Experience in Accessible Tourism: Designing a Mobile Application for the Deaf and Hard of Hearing
Authors: Alegro Tjaša , Ilić Marica , Rančić Demir Milica
Published: October 2022

How someone experiences a tourist experience depends on several factors. This article will focus on ways to ensure active participation and thus a pleasant and memorable experience for people with disabilities, specifically people with hearing problems – the deaf and hard of hearing. With the development of ICT technology, the possibilities for developing tourist products intended for the deaf and hard of hearing are even greater and can be friendlier to them. Various mobile applications complement a city’s tourist products and services and are more than a welcome help for people with special needs. With an innovative Design Thinking method suitable for planning projects or designing services or products intended for end users, we designed an idea for a mobile application for Ljubljana that is tailored to deaf and hard of hearing tourists, as Slovenia does not yet have a similar application. We designed the product idea based on an overview of good practices. Through five phases of the Design Thinking method, we analysed the indispensable elements of the mobile application for deaf and hard of hearing tourists and evaluated it through the HEART framework matrix developed for user experience assessment.
Wine Tourism as a Type of Well-being Tourism – Literature Review
Authors: Potočnik Topler Jasna , Petek Vita
Published: October 2022

The purpose of this study is to examine the effects of wine tourism on well-being. Wine tourism includes many activities, and not only wine tastings, perhaps paired with food tastings. It includes hiking and biking in the vineyards, reading literature on wine (fiction and non-fiction), attending seminars and conferences on wine, getting acquainted with new landscapes and socializing with others. Another issue relates to whether wine, particularly red wine, confers additional health benefits. Within the Mediterranean diet, wine seems to be an essential component. The starting point for wine and health studies was the “French Paradox”, which suggests that consuming red wine daily not only helps the cardiovascular system, but also increases lifespan due to the resveratrol found in the skins and tannins of red grapes. Recent evidence suggests that wine consumption is correlated with less stress and prevention of the development of certain cancers.
Literary Walking Tours as a Form of Well-being: Slovene Writers' Trail and the Prežihov Voranc Route
Authors: Potočnik Topler Jasna
Published: October 2022

The concept of literary tourism is becoming increasingly interesting, not only for researchers and students, but also for tourism practitioners and destination managers, who are interested in the supply of and demand for this sub-type of cultural tourism. In recent decades, it has become an important niche in tourism. Especially in rural areas it is perceived as useful in supporting the existent tourism activities and helping to develop new ones. Not only is it prose, drama and poetry that inspire people to become literary tourists, but also biographies and autobiographies, screen adaptations of literary works, theatre performances, etc. Literary walking tours have emerged as a well-received type of literary tourism product, which have been associated to well-being. Some of them are also included in the most popular tour guides, such as, for example, The Lonely Planet.
Prevalence and prediction of augmented renal clearance in the neurocritical care population
Authors: Cook Aaron M. , Li David , Nestor Melissa A. , Bastin Melissa L. Thompson
Published: October 2022

Background: Augmented renal clearance (ARC; creatinine clearance [CrCl] >130 mL/min/1.73 m2) is prevalent in patients with neurological injuries and may influence their exposure to important pharmacological therapies. Little is known about the relationship between estimated and measured CrCl in this population.Methods: This single-center, prospective, observational cohort study aimed to describe the association between ARC and estimated CrCl and neurological outcomes in a broad neurocritical care population. Prospective patient screening criteria included adults aged 18–85 years, with critical illness due to neurologic causes (such as ischemic stroke or subarachnoid hemorrhage) and lack of renal dysfunction on admission. Patients who had at least one urine CrCl measurement performed within the first 7 days of hospitalization were included. Two cohorts were evaluated: those with ARC and those without ARC. Results: Fifty-seven patients were included, of whom 49 (86%) exhibited ARC. Subjects with ARC were more likely to be male and had a significantly higher median measured CrCl (201.7 mL/min/1.73 m2) than those without ARC (109.8 mL/min/1.73 m2). The Augmented Renal Clearance in Trauma Intensive Care (ARCTIC) score displayed the strongest association (vs. CrCl equations) with ARC development (area under the receiver operating characteristic curve, 0.648). Conclusion: The prevalence of ARC in the present study of a broad neurocritical care population appeared to be high (86%). The ARCTIC score had higher sensitivity and specificity for diagnosing ARC than the common serum creatinine-based estimation.
The Concept of Yoga in the Tattwa Jñana Script
Authors: Widya Sena I Gusti Made
Published: October 2022

Various lontar and Tattwa scripts in Bali are the fruit of local wisdom inspired by the teachings of the Vedic scriptures. This local script is based on the truth that has been guiding most Balinese people. One of the Tattwa truths written in the Vedas is the concept of yoga as a means to attain spiritual awareness. Yoga offers a holistic, practical and religious approach that aims to help all components of the body work together in harmony. This text contains theology, cosmology, and practice of the teachings of Prayogasandhi (tapa, brata, yoga and samadhi) knowledge to save souls from misery. This study aims to understand the concept of Yoga in the Tattwa Jñana Script as a way to achieve spiritual awareness. The theory used is structural theory and semiotic theory. This study uses the method of collecting data documents and literature. The data analysis technique was carried out qualitatively by describing it descriptively. The results of this study indicate that: (1) The Tattwa Jñana script consists of prose which is divided into several chapters, and consists of 74 slokas in Old Javanese. (2) The concept of yoga in the Tattwa Jñana script is Prayogasandhi. Prayogasandhi is a means to attain spiritual awareness through tapas, brata, yoga and samadhi to Iswara (God). Prayogasandhi needs to be followed by discipline, true knowledge (samyagjna) and contemplation.
Study of Physico-chemical Properties in Industrial Areas of Chambal Region Soil
Authors: Gupta Akanksha , Chitranshi Swati , Dwivedi Alok , Johri Sonia
Published: October 2022

Background: Soil is a crucial and remarkable component of the terrestrial ecosystems. The objective of this study is to analyze macronutrients and micronutrients in order to understand the suitability of soil for cultivation of crops in the selected sites. In the present study the physicochemical analysis was carried out by analyzing the parameters i.e. pH, organic carbon and potassium etc. Methods: Four soil samples were collected in 2017-2018 during the winter season at different locations in industrial areas of the Chambal region and compared with the standard value of soil quality. The micronutrients Fe, Cu, Mn and Zn were determined by using atomic absorption spectrophotometer. Result: Organic carbon was observed in a range between 0.51 to 0.55%. The soil pH was observed neutral to slightly alkaline in nature (7.2-7.6). All the parameters were under the permissible limit of soil quality standard except the phosphorus which was found to be less than minimum requirement ( less than 28 kg ha-1). Pearson’s correlation matrix result demonstrated that several physicochemical characteristics of soil were having a positive association, particularly soil pH, were correlated with EC and sand content. Organic matter and organic carbon had positive and significant correlation with nitrogen, phosphorus, potassium and iron. Organic matter and fertility of soil was significantly correlated. Therefore, the proper study of soil provided the information about its fertility and crop productivity.
Effect of Supplementation of Bovine Placental Powder on Testicular Tissue and Spermatozoa in Aging Rat Model
Authors: Sihotang Y.A.M.A. , Prihatno S.A. , Budipitojo T. , Adi Y.K.
Published: October 2022

Background: Aging in the male reproductive system can cause testicular degeneration. Nowadays, regenerative medicine is a developing domain. This study is conducted to describe the potential effects of dried bovine placenta supplementation on the percentage of abnormal spermatozoa, the density of seminiferous tubules luminal content and Leydig cells counts in D-galactose-induced reproductive aging in male rats. Methods: A total of 15 healthy adult male Wistar rats were used in this study. Rats were randomly divided into three groups, A: healthy control, B: D-galactose treated, C: D-galactose treated and supplemented with 10% dried bovine placenta. The percentage of abnormal spermatozoa, density of seminiferous tubules luminal content and Leydig cells count were determined. One-Way ANOVA was used for statistical analysis. Result: The average per cent of abnormal spermatozoa did not differ. The seminiferous tubule proportion with full luminal density in Group C (55.2%) was higher than Group B (31.8%, P=0.001) but relatively similar to Group A (62%, P=0.513). The seminiferous tubule proportion with medium luminal density in Group C (23.3%) was lower than Group B (34.2%, P=0.016) but relatively similar to Group A (25.8%, P=1.000). The seminiferous tubule proportion with low luminal density in Group C (21.5%) was lower than Group B (34.0%, P=0.016) but relatively similar to Group A (13.4%, P=0.139). The average number of Leydig cells counted did not differ. In conclusion, supplementation of 10% dried bovine placenta improved the density of seminiferous tubules luminal content in D-galactose-induced reproductive aging in male rats.
Renewal Of Arabic Grammar (Nahw) By Al-Shatibi In Al Maqashid Al Syafiyah
Authors: Nurdianto Talqis , Ritonga Mahyudin
Published: October 2022

Learning Arabic to non-Arabic makes nahw (Arabic syntax) an important part that cannot be overlooked. The formulation of nahw renewal occurred in line with differences of opinion from previous scholars. As nahw developed as a science, its discussion became more complex and obscure. The emergence of the Basran and Kufan schools drove fanaticism among scholars, and their debates revolved around increasingly complex topics. While these discourses expanded the knowledge body of nahw, those grammarians did not propose anything novel, and its topics soon became incomprehensible to non-Arab learners. There was, therefore, a great urgency to reform and simplify nahw for such learners. Within this context, this study attempts to examine the innovative methods introduced by al-Shatibi to simplify and rejuvenate nahw through his book al-Maqashid al-Shafiah fi Sharh al-Khulashah al-Kafiah. To achieve this objective, data were obtained through library research, primarily from Al-Shatibi's text and other related sources. The findings revealed that Al-Shatibi's diverse educational background allowed him to elucidate the principles through simple, straightforward sentences. His method in al-Maqashid was distinctive: He cited all the differing opinions in a given problem, supporting some while criticizing the others; his deep understanding of Alfiyah allowed him to clarify its implicit meanings; his excellence in fiqh and other sciences manifested in his commentary of some nahw problems; and he employed exemplary expressions in his writings, such as explicitly selecting a rule or opinion and not being vague, stating his preferred opinions, and implicitly deciding on an opinion. Al-Shatibi's educational approach, employing questions and answers, hypothetical arguments and counters, and systematic organization allowed non-Arabs to benefit significantly from the book.
From EFL to ELF: In the Need to Incorporate Principles of English as a Lingua Franca in Colombian ELT
Authors: Mosquera Pérez Jhon Eduardo
Published: October 2022

English as a lingua franca is a phenomenon that has been gaining importance in the last few years. In the international scenario, scholarly literature has already explored the possible benefits of incorporating ELF in the ELT field. In Colombia, however, the empirical and conceptual studies on this area are scarce. Keeping this in mind, this reflective article discusses the possibility of progressively incorporating ELF in the Colombian ELT. In the first place, what ELF is, is analyzed, and this and other terms that have been used to refer to this linguistic phenomenon are differentiated. Second, some of the areas that need to take into consideration (materials design, assessment practices, to mention a few) are presented if we want to integrate ELF in Colombian ELT. Finally, some conclusions are presented, as well as potential research scenarios regarding ELF
Reflexiones sobre la Construcción Discursiva de la Identidad del Profesor de Idiomas
Authors: Sánchez Hernández Diana Iveth
Published: October 2022

Este artículo presenta algunas reflexiones acerca de la construcción de la identidad del maestro universitario de idiomas y de su discurso. El interés por el tema nace de una reflexión sobre la propia evolución de mi identidad como docente, y se sitúa en el contexto de una investigación doctoral más amplia sobre la construcción discursiva de la identidad del profesor de idiomas que tiene como objetivo investigar cómo, a través del discurso, podemos reflejar no solo quienes somos (o al menos, quienes creemos que somos), la forma en que nos vemos, y cómo queremos que los demás nos perciban, sino también cómo tal discurso es el material de construcción de aquello mismo que buscamos reflejar. En esta contribución se detallan brevemente algunas bases teóricas y los antecedentes históricos de la enseñanza de idiomas en México, específicamente en dos universidades: la Universidad Nacional Autónoma de México y la Universidad Veracruzana
Proof of The Collatz Conjecture
Authors: Sukuşu Bülent
Published: October 2022

Collatz conjecture (or 3n+1 problem) has been explored for about 85 years. In this article, we prove the Collatz conjecture. We will show that this conjecture is valid for all positive integers by performing the Collatz inverse operation on the numbers that comply with the rules of the Collatz conjecture. Finally, it will be proved that there are no positive integers that do not comply with this conjecture.
Differential Effects of Chronic Methamphetamine Treatment on High-Frequency Oscillations and Responses to Acute Methamphetamine and NMDA Receptor Blockade in Conscious Mice
Authors: Hudson Matthew , Foreman Joshua , Rind Gil , Manning Elizabeth , Jones Nigel , Van den Buuse Maarten
Published: October 2022

Dysregulation of high-frequency neuronal oscillations has been implicated in the pathophysiology of schizophrenia. Chronic methamphetamine (METH) use can induce psychosis similar to paranoid schizophrenia. The current study in mice aimed to determine the effect of chronic METH treatment on ongoing and evoked neuronal oscillations. C57BL/6 mice were treated with METH or vehicle control for three weeks and implanted with extradural recording electrodes. Two weeks after the last METH injection, mice underwent three EEG recording sessions to measure ongoing and auditory-evoked gamma and beta oscillatory power in response to an acute challenge with METH (2mg/kg), the NMDA receptor antagonist MK-801 (0.3mg/kg), or saline control. A separate group of mice pretreated with METH showed significantly greater locomotor hyperactivity to an acute METH challenge, confirming long-term sensitisation. Chronic METH did not affect ongoing or evoked gamma or beta power. Acute MK-801 challenge reduced ongoing beta power whereas acute METH challenge significantly increased ongoing gamma power. Both MK-801 and METH challenge suppressed evoked gamma power. Chronic METH treatment did not modulate these acute drug effects. There were minor effects of chronic METH and acute METH and MK-801 on selected components of event-related potential (ERP) waves. In conclusion, chronic METH treatment did not exert neuroplastic effects on the regulation of cortical gamma oscillations in a manner consistent with schizophrenia, despite causing behavioural sensitisation.
An fNIRS Study of Applicability of The Unity-Diversity Model of Executive Functions in Preschoolers
Authors: Xie Sha , Gong Chaohui , Lu Jiahao , Zhang Hao , Wu Dandan , Chi Xinli , Li Hui , Chang Chunqi
Published: October 2022

This study examined the relationship among the three domains of executive function (EF; cognitive shifting, inhibitory control, and working memory) to test the applicability of the unity-diversity model in preschoolers using both behavioral and fNIRS approaches. Altogether 58 Chinese preschoolers (34 boys, 24 girls, Mage = 5.86 years, SD = 0.53, Age range = 4.83-6.67 years) were administered the Dimensional Card Change Sort (DCCS), go/no-go, and missing scan task. Their brain activations in the prefrontal cortex during the tasks were examined using fNIRS. First, the behavioral results indicated that the missing scan task scores (working memory) correlated with the DCCS (cognitive shifting) and go/no-go tasks (inhibitory control). But the latter two did not correlate with each other. Second, the fNIRS results demonstrated that the prefrontal activations during the working memory task correlated with those in the same regions during the cognitive shifting and inhibitory control tasks. Still, the latter two did not correlate. The behavioral and neuroimaging evidence jointly indicates that the unity-diversity model of EF does apply to Chinese preschoolers.
HIV/AIDS Mathematical Model of Triangle Transmission
Authors: Espitia Morillo Cristian Camilo , Meyer João Frederico da Costa Azevedo
Published: October 2022

In this paper mathematical analysis of the HIV/AIDS deterministic model exposed in [Espitia, C. et. al. Mathematical Model of HIV/AIDS Considering Sexual Preferences Under Antiretroviral Therapy, a Case Study in San Juan de Pasto, Colombia, Journal of Computational Biology 29 (2022) 483–493] is made. The objective is to gain insight into the qualitative dynamics of the model determining the conditions for the persistence or effective control of the disease in the community through the study of basic properties such as positiveness and boundedness, calculus of basic reproduction number, stationary points such as disease free equilibrium (DFE), boundary equilibrium (BE) and endemic equilibrium (EE) are calculated, local stability (LAS) of disease free equilibrium. It research allow to conclude that the best way to reduce contagion and consequently to reach a DFE is thought to be the reduction of homosexual partners rate as they are the most affected population by the virus, and are therefore the most likely to become infected and to spread the infection. Increasing the departure rate of infected individuals, leads to a decrease in untreated infected heterosexual men and untreated infected women.