bluuebunny/crossref_metadata_2025 huggingface dataset:
Prophylactic HPV vaccination: past, present, and future
Authors: CASTLE P. E. , MAZA M.
Published: October 2015

Human papillomavirus (HPV) is the necessary cause of cervical cancer, the fourth most common cancer and cause of cancer-related death in females worldwide. HPV also causes anal, vaginal, vulvar, penile, and oropharyngeal cancer. Prophylactic HPV vaccines based on recombinantly expressed virus-like particles have been developed. Two first-generation, U.S. Food and Drug Administration (FDA)-approved vaccines prevent infections and disease caused by HPV16 and HPV18, the two HPV genotypes that cause approximately 70% of cervical cancer, and one of these vaccines also prevents HPV6 and HPV11, the two HPV genotypes that cause 90% of genital warts. A next-generation vaccine, recently approved by the U.S. FDA, targets HPV16, HPV18, and five additional HPV genotypes that together causes approximately 90% of cervical cancer as well as HPV6 and HPV11. In clinical trials, these vaccines have shown high levels of efficacy against disease and infections caused by the targeted HPV genotypes in adolescent females and males and older females. Data indicate population effectiveness, and therefore cost effectiveness, is highest in HPV-naive young females prior to becoming sexually active. Countries that implemented HPV vaccination before 2010 have already experienced decreases in population prevalence of targeted HPV genotypes and related anogenital diseases in women and via herd protection in heterosexual men. Importantly, after more than 100 million doses given worldwide, HPV vaccination has demonstrated an excellent safety profile. With demonstrated efficacy, cost-effectiveness, and safety, universal HPV vaccination of all young, adolescent women, and with available resources at least high-risk groups of men, should be a global health priority. Failure to do so will result in millions of women dying from avertable cervical cancers, especially in low- and middle-income countries, and many thousands of women and men dying from other HPV-related cancers.
A 16-year-old with ST elevation myocardial infarction: case report and review of the literature
Authors: Hill Dustin , Waldman Adam , Vivek Deepak
Published: October 2015

Chest pain in young adults presents a unique diagnostic challenge, placing young patients at an increased risk to be misdiagnosed, as this patient population typically does not demonstrate the traditional risk factors associated with cardiovascular disease. This study details the case of a 16-year-old male who presented with new-onset chest pain and ST elevation on electrocardiogram. His history was unremarkable for known cardiac risk factors, but laboratory evaluation demonstrated markedly elevated troponins and electrocardiographic findings confirmed ST-segment elevation myocardial infarction. Coronary angiography demonstrated 100% occlusion of the left anterior descending artery, which was managed with percutaneous transluminal coronary angioplasty, thrombectomy, and bare-metal stenting. The patient had an uneventful recovery. This study examines the major causes of ST elevation myocardial infarction in young adults and reviews the major differences between younger and older myocardial infarction populations with emphasis on risk factor profile, pathophysiological mechanisms, clinical presentation, angiographic findings, and prognosis. This review highlights the need for consideration of a wide differential in younger subsets of the population presenting with chest pain and ST elevation. The implementation of current adult management protocols and guidelines for ST elevation myocardial infarction should not be overlooked due to age. Given the potential for premature death and long-term disability with resulting individual and societal consequences, it is crucial to understand the importance of correct diagnostic evaluation in this clinical scenario.
Identification of Organic Binders in Ancient Chinese Paintings by Immunological Techniques
Authors: Hu Wenjing , Zhang Hui , Zhang Bingjian
Published: October 2015

The identification and localization of organic binders in artworks are big challenges in archaeology and conservation science. Immunological techniques, such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence microscopy (IFM) have the potential to become powerful tools for the analysis of organic materials in ancient samples. In this study, ELISA and IFM techniques were combined to identify chicken ovalbumin, glue from several mammalian species, bovine milk, and fish glue in ancient Chinese painting samples. As binders, egg ovalbumin was found in two painting samples and animal glue was found in three samples, which were dated from the 4th to 8th centuries. The results clearly demonstrate that ELISA and IFM can be used to validate results from ancient samples.
EFFECTS OF SURFACE TENSION ON TRAPPED MODES IN A TWO-LAYER FLUID
Authors: SAHA S. , BORA S. N.
Published: October 2015

We consider a two-layer fluid of finite depth with a free surface and, in particular, the surface tension at the free surface and the interface. The usual assumptions of a linearized theory are considered. The objective of this work is to analyse the effect of surface tension on trapped modes, when a horizontal circular cylinder is submerged in either of the layers of a two-layer fluid. By setting up boundary value problems for both of the layers, we find the frequencies for which trapped waves exist. Then, we numerically analyse the effect of variation of surface tension parameters on the trapped modes, and conclude that realistic changes in surface tension do not have a significant effect on the frequencies of these.
‘I WILL BUILD A BLACK EMPIRE’: THE BIRTH OF A NATION AND THE SPECTER OF THE NEW NEGRO
Authors: Baldwin Davarian L.
Published: October 2015

In the penultimate scene to D. W. Griffith's The Birth of a Nation, the normally composed and gentlemanly mulatto Lieutenant Governor Silas Lynch can no longer contain himself. He has become the leader of a rising “black South.” “[D]runk with wine and power,” his maddening ambition for political dominion seethes over into the ultimate desire that seems to drive any black male quest for authority throughout the film: Lynch exclaims, “I want to marry a white woman!” True to the deceptive nature of the duplicitous mulatto, he does not want to marry just any white woman but Elsie, the daughter of his abolitionist mentor, Austin Stoneman. Though Elsie comes from a lineage of radical advocates for equal rights, a proposal of marriage goes too far and she jerks away, offering him only a “horsewhipping for his insolence.” Lynch is outraged. Her rejection sends him into a lecherous frenzy, determined to abduct Elsie if she will not come willingly. For a moment, he regains some composure and with a snide veneer of arrogance, saunters over to the window and pulls back the curtain to reveal white residents cowering in fear to an overwhelming and bloodthirsty reign of black terror. Lynch points outside and proclaims: “See! My people fill the streets. With them I will build a Black Empire and you as a Queen shall sit by my side.”
OLD PURPOSE, “NEW BODY”:THE BIRTH OF A NATION AND THE REVIVAL OF THE KU KLUX KLAN
Authors: Lennard Katherine
Published: October 2015

When a recruiter for the Ku Klux Klan first arrived in Butte, Montana, in the summer of 1921, he placed an ad in the Butte Miner depicting a white-robed man astride a bucking horse. Borrowed from the publicity materials for D W. Griffith's groundbreaking film, The Birth of a Nation (1915), this image of a uniformed figure was a fixture of Klan propaganda. The advertisement faced two directions: it connected the newly formed Klan with its Reconstruction Era predecessor, while also demonstrating that the Klan imagined itself through the revisionist lens of Griffith's film and its textual inspiration, Thomas Dixon Jr.'s play and novel The Clansman (1905). The image of a white-robed Klansmen in the Butte Miner was thus a symbol of what Klan leaders and the popular media alike called the Klan's “revival,” the process through which the historical organization was brought to life in a new form.
Principled Silence or Mere Silence on Principles? The Role of the EU Charter’s Principles in the Case Law of the Court of Justice
Authors: Krommendijk Jasper
Published: October 2015

Historical background of the inclusion of social rights in the Charter of Fundamental Rights – Distinction between rights and principles – Similarities between the conditions for direct effect and the criteria for distinguishing between Charter rights and principles – Implications of this distinction for the possibilities of judicial review – Reluctance of the ECJ to explicitly deal with the distinction until Glatzel, as illustrated by its earlier judgments in Dominguez and AMS.
First record of the genus Umimayanthus from Palau and Micronesia
Authors: Montenegro Javier , Lorion Julien , Reimer James Davis
Published: October 2015

Until recently, the only sponge-associated genera in the order Zoantharia wereParazoanthus(family Parazoanthidae),EpizoanthusandThoracactis(family Epizoanthidae), both within the suborder Macrocnemina. The taxonomy of the genusParazoanthus,as originally described, has been undergoing revision since 2010, with several species, genera and even families described. In 2015, multiple molecular markers were used in combination with morphological characteristics to erect the genusUmimayanthusinside the family Parazoanthidae. It included three species described from southern Japan, with other records for some of the species from the Great Barrier Reef, New Caledonia and the Red Sea. However, little is known of its distribution in the Pacific Islands. Here we report on the finding ofUmimayanthusspecimens in Palau, Micronesia, representing the first records for this region. A total of 32 specimens ofUmimayanthuswere collected from seven different locations; eight of the specimens were identified asUmimayanthus chanpuru,while the remaining 24 colonies were only identified to genus level.
Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities
Authors: Luciano Michelle , Marioni Riccardo E. , Valdés Hernández Maria , Muñoz Maniega Susana , Hamilton Iona F. , Royle Natalie A. ,   Generation Scotland, Chauhan Ganesh , Bis Joshua C. , Debette Stephanie , DeCarli Charles , Fornage Myriam , Schmidt Reinhold , Ikram M. Arfan , Launer Lenore J. , Seshadri Sudha ,   the CHARGE Consortium, Bastin Mark E. , Porteous David J. , Wardlaw Joanna , Deary Ian J.
Published: October 2015

Structural brain magnetic resonance imaging (MRI) traits share part of their genetic variance with cognitive traits. Here, we use genetic association results from large meta-analytic studies of genome-wide association (GWA) for brain infarcts (BI), white matter hyperintensities, intracranial, hippocampal, and total brain volumes to estimate polygenic scores for these traits in three Scottish samples: Generation Scotland: Scottish Family Health Study (GS:SFHS), and the Lothian Birth Cohorts of 1936 (LBC1936) and 1921 (LBC1921). These five brain MRI trait polygenic scores were then used to: (1) predict corresponding MRI traits in the LBC1936 (numbers ranged 573 to 630 across traits), and (2) predict cognitive traits in all three cohorts (in 8,115–8,250 persons). In the LBC1936, all MRI phenotypic traits were correlated with at least one cognitive measure, and polygenic prediction of MRI traits was observed for intracranial volume. Meta-analysis of the correlations between MRI polygenic scores and cognitive traits revealed a significant negative correlation (maximal r = 0.08) between the HV polygenic score and measures of global cognitive ability collected in childhood and in old age in the Lothian Birth Cohorts. The lack of association to a related general cognitive measure when including the GS:SFHS points to either type 1 error or the importance of using prediction samples that closely match the demographics of the GWA samples from which prediction is based. Ideally, these analyses should be repeated in larger samples with data on both MRI and cognition, and using MRI GWA results from even larger meta-analysis studies.
Einstellungen und Reaktanzerleben bei geglückter und misslungener Partizipation
Authors: Mende Stephan , Wegge Jürgen , Jeppesen Hans Jeppe , Jønsson Thomas , Unterrainer Christine
Published: October 2015

Zusammenfassung. Prozesse betrieblicher Partizipation sind für die Persönlichkeitsentwicklung wichtig. Doch wie werden solche Zusammenhänge vermittelt und welche Rolle spielen Unterschiede zum Wunsch nach Mitsprache? Zur Untersuchung dieser Fragen nahmen 46 Arbeitnehmer an einer Laborstudie teil, in der Reaktanzerlebnisse bei der Einräumung vs. Blockierung von Mitbestimmungsmöglichkeiten ermittelt wurden. Der zuvor bei der Arbeit erlebte und gewünschte Einfluss wurde mit dem Fragebogen von Jeppesen, Jønsson und Shevlin (2010) erfasst, der als Akteur die eigene Person und andere Agenten (z. B. Betriebsrat) anspricht. Die Befunde bestätigten die erwarteten Zusammenhänge zwischen Einfluss und Kontrollablehnung bzw. arbeitsbezogener Identifikation. Diese werden durch die arbeitsbezogene Selbstwirksamkeit vermittelt. Bei der Blockierung von Mitsprache erlebten Personen mehr Reaktanz, wenn sie viel Einfluss an ihrem Arbeitsplatz hatten. Beim Wunsch nach Partizipation macht es einen großen Unterschied, welcher Akteur präferiert wird. Angesichts dieser Befunde kann das Instrument von Jeppesen et al. (2010) für eine genauere Analyse partizipativer Prozesse auch in Deutschland empfohlen werden.
Wie bilden Personalpraktiker/innen sich weiter?
Authors: Kanning Uwe P. , Thielsch Meinald T.
Published: October 2015

Zusammenfassung. Im Rahmen einer Online-Befragung von 199 Personalpraktikern wird deren Weiterbildungsverhalten untersucht. Nach eigener Einschätzung greifen die Befragten bei der Lösung von rund einem Viertel ihrer Arbeitsaufgaben auf Wissen zurück, das sie in der Weiterbildung erworben haben. Dabei spielen Print- und Onlinemedien eine herausgehobene Rolle. Personalpraktiker mit Psychologiestudium lesen in signifikant stärkerem Maße (wissenschaftliche) Fachzeitschriften als Vertreter anderer Berufsgruppen, wobei deutschsprachige Publikationen bei allen Berufsgruppen präferiert werden. Für einen leichteren Transfer wissenschaftlicher Erkenntnisse in die Praxis erscheinen auf Basis dieser Studie die folgenden Punkte besonders wichtig: (1) Die wissenschaftlichen Befunde müssen so dargestellt werden, dass ihr Praxisbezug offen zu Tage tritt. (2) Sie müssen aktuelle Themen aufgreifen, (3) deutschsprachig publiziert werden und (4) leicht verfügbar sein.
Behavioral Testing of Mice Concerning Anxiety and	Depression
Authors: Schweinfurth Nina , Lang Undine E.
Published: October 2015

Abstract. In the development of new psychiatric drugs and the exploration of their efficacy, behavioral testing in mice has always shown to be an inevitable procedure. By studying the behavior of mice, diverse pathophysiological processes leading to depression, anxiety, and sickness behavior have been revealed. Moreover, laboratory research in animals increased at least the knowledge about the involvement of a multitude of genes in anxiety and depression. However, multiple new possibilities to study human behavior have been developed recently and improved and enable a direct acquisition of human epigenetic, imaging, and neurotransmission data on psychiatric pathologies. In human beings, the high influence of environmental and resilience factors gained scientific importance during the last years as the search for key genes in the development of affective and anxiety disorders has not been successful. However, environmental influences in human beings themselves might be better understood and controllable than in mice, where environmental influences might be as complex and subtle. The increasing possibilities in clinical research and the knowledge about the complexity of environmental influences and interferences in animal trials, which had been underestimated yet, question more and more to what extent findings from laboratory animal research translate to human conditions. However, new developments in behavioral testing of mice involve the animals’ welfare and show that housing conditions of laboratory mice can be markedly improved without affecting the standardization of results.
Subtle Impact of Akt1 and Akt3 on Exploratory Behavior in Gene	Targeted Mice
Authors: Leibrock Christina , Hierlmeier Michael , Lang Undine E. , Lang Florian
Published: October 2015

Abstract. The present study explored the impact of Akt1 and Akt3 on behavior. Akt1 (akt1-/-) and Akt3 (akt3-/-) knockout mice were compared to wild type (wt) mice. The akt1-/- mice, akt3-/- mice, and wt mice were similar in most parameters of the open-field test. However, the distance traveled in the center area was slightly but significantly less in akt3-/- mice than in wt mice. In the light/dark transition test akt1-/- mice had significantly lower values than wt mice and akt3-/- mice for distance traveled, number of rearings, rearing time in the light area, as well as time spent and distance traveled in the entrance area. They were significantly different from akt3-/- mice in the distance traveled, visits, number of rearings, rearing time in the light area, as well as time spent, distance traveled, number of rearings, and rearing time in the entrance area. In the O-maze the time spent, and the visits to open arms, as well as the number of protected and unprotected headdips were significantly less in akt1-/- mice than in wt mice, whereas the time spent in closed arms was significantly more in akt1-/- mice than in wt mice. Protected and unprotected headdips were significantly less in akt3-/- mice than in wt mice. In closed area, akt3-/- mice traveled a significantly larger distance at larger average speed than akt1-/- mice. No differences were observed between akt1-/- mice, akt3-/- mice and wt-type mice in the time of floating during the forced swimming test. In conclusion, akt1-/- mice and less so akt3-/ mice display subtle changes in behavior.
From Animal Behavior to Human Health
Authors: Schramm Elisabeth , Hediger Karin , Lang Undine E.
Published: October 2015

Abstract. Animal-assisted therapy (AAT) has been shown to be effective in recent meta-analyses with an improvement of mental health, quality of life, and a decrease in the sense of isolation. Reduction of depressive symptoms in human beings is one of the most beneficial outcomes of AAT. For relapse prevention in depression, conventional mindfulness programs such as mindfulness-based Cognitive Therapy(MBCT) proved to be useful, but are often difficult to learn and produce high dropout rates in high risk patients. For this patient group, the teaching of mindfulness skills was facilitated by using sheep in an open pilot study. Six partially or unstable remitted patients with early trauma participated in eight group sessions of a nature and animal-assisted mindfulness training. The approach was feasible and highly accepted by participants with no dropouts. The results show a decrease of depressive symptoms and rumination, an improvement of overall mindfulness skills, but not of acceptance skills. Further studies using randomized controlled designs are warranted.
Immunological evidence and regulatory potential for cell‐penetrating antibodies in intravenous immunoglobulin
Authors: Sali Aggeliki D , Karakasiliotis Ioannis , Evangelidou Maria , Avrameas Stratis , Lymberi Peggy
Published: October 2015

Anti‐DNA cell‐penetrating autoantibodies have been extensively studied in autoimmune but not in normal sera. We investigated herein the presence and properties of cell‐penetrating antibodies (CPAbs) in intravenous immunoglobulin (IVIg), a blood product of pooled normal human IgG. IVIg cell penetration was observed into various cell lines, as well as cells from several organs of mice injected intravenously with IVIg therapeutic dose. In all cell types examined in vitro and in vivo, intracellular IgG localized in the cytoplasm, in contrast to the nuclear accumulation of disease‐related CPAbs. IVIg was found to rapidly enter cells via an energy‐independent mode. The CPAb‐fraction was isolated and found to be polyreactive to nuclear and cytoplasmic components; although it corresponded to ~2% of IVIg, it accounted for its inhibitory effect on splenocyte activation. Investigation of IVIg cell penetration capacity provides insight into its mechanisms of action and may account for some of its beneficial effects in numerous diseases.
Bacterial diversity and community composition from seasurface to subseafloor
Authors: Walsh Emily A , Kirkpatrick John B , Rutherford Scott D , Smith David C , Sogin Mitchell , D’Hondt Steven
Published: October 2015

We investigated compositional relationships between bacterial communities in the water column and those in deep-sea sediment at three environmentally distinct Pacific sites (two in the Equatorial Pacific and one in the North Pacific Gyre). Through pyrosequencing of the v4–v6 hypervariable regions of the 16S ribosomal RNA gene, we characterized 450 104 pyrotags representing 29 814 operational taxonomic units (OTUs, 97% similarity). Hierarchical clustering and non-metric multidimensional scaling partition the samples into four broad groups, regardless of geographic location: a photic-zone community, a subphotic community, a shallow sedimentary community and a subseafloor sedimentary community (⩾1.5 meters below seafloor). Abundance-weighted community compositions of water-column samples exhibit a similar trend with depth at all sites, with successive epipelagic, mesopelagic, bathypelagic and abyssopelagic communities. Taxonomic richness is generally highest in the water-column O2 minimum zone and lowest in the subseafloor sediment. OTUs represented by abundant tags in the subseafloor sediment are often present but represented by few tags in the water column, and represented by moderately abundant tags in the shallow sediment. In contrast, OTUs represented by abundant tags in the water are generally absent from the subseafloor sediment. These results are consistent with (i) dispersal of marine sedimentary bacteria via the ocean, and (ii) selection of the subseafloor sedimentary community from within the community present in shallow sediment.
Pd(OAc)2/SPPh3 accelerated activation of gem-dichloroalkenes for the construction of 3-arylchromones
Authors: Liu Jianming , Song Weiwei , Yue Yuanyuan , Liu Ren , Yi Hong , Zhuo Kelei , Lei Aiwen
Published: October 2015

The Pd-catalyzed regioselective intramolecular nucleophilic substitution of gem-dichloroalkene derivatives with salicylaldehydes leading to the synthesis of 3-arylchromones has been developed.
When protein-based biomineralization meets hydrothermal synthesis: the nanostructures of the as-prepared materials are independent of the protein types
Authors: Wang Liqiang , Li Xiangzhi , Jiang Xingxing , Chen Wansong , Hu Lanshuang , Walle Maru Dessie , Deng Liu , Yang Minghui , Liu You-Nian , Kirin Srećko I.
Published: October 2015

Proteins were proved to be type-independent templates for the biomineralization of iron ions into hematite mesocrystals with tunable structures and morphologies under hydrothermal conditions.
The rational design of a peptide-based hydrogel responsive to H2S
Authors: Peltier Raoul , Chen Ganchao , Lei Haipeng , Zhang Mei , Gao Liqian , Lee Su Seong , Wang Zuankai , Sun Hongyan
Published: October 2015

By introducing an azidobenzyl moiety into an ultrashort hydrogelating peptide, we reported on the design of a novel hydrogel that could be selectively degraded by H2S under physiological conditions.
Detecting biologically relevant phosphates with locked salicylaldehyde probes in water
Authors: Kumari Namita , Zelder Felix
Published: October 2015

This communication describes a disassembly based approach for the detection of biologically relevant di- and tri-phosphates in water using locked fluorescent salicylaldehyde probes.
Stereospecific SN2@P reactions: novel access to bulky P-stereogenic ligands
Authors: Orgué Sílvia , Flores-Gaspar Areli , Biosca Maria , Pàmies Oscar , Diéguez Montserrat , Riera Antoni , Verdaguer Xavier
Published: October 2015

Hydrolysis of bulky aminophosphine boranes followed by nucleophilic substitution of the resulting phosphinous acid boranes provides a novel access to P*-ligands. Using this methodology, a P*,N ligand was synthesized and applied to the asymmetric Ir-catalyzed hydrogenation.
A new family of wurtzite-phase Cu2ZnAS4−x and CuZn2AS4 (A = Al, Ga, In) nanocrystals for solar energy conversion applications
Authors: Ghosh Anima , Palchoudhury Soubantika , Thangavel Rajalingam , Zhou Ziyou , Naghibolashrafi Nariman , Ramasamy Karthik , Gupta Arunava
Published: October 2015

A new family of semiconductors Cu2ZnAS4−x and CuZn2AS4 (A = Al, Ga, In) that absorb strongly at visible wavelengths has been synthesized as nanocrystals.
Theoretical model of the interaction of glycine with hydrogenated amorphous carbon (HAC)
Authors: Timón Vicente , Gálvez Óscar , Maté Belén , Tanarro Isabel , Herrero Víctor J. , Escribano Rafael
Published: October 2015

A theoretical model of hydrogenated amorphous carbon (HAC) is developed and applied to study the interaction of glycine with HAC surfaces at astronomical temperatures.
Improved conductivity of NdFeO3through partial substitution of Nd by Ca: a theoretical study
Authors: Wang You , Wang Yun , Ren Wei , Liu Porun , Zhao Huijun , Chen Jun , Deng Jinxia , Xing Xianran
Published: October 2015

First-principles theoretical analysis of the electronic structure of NdxCa1−xFeO3−σ(x= 0.00, 0.25, 0.50, 0.75 or 1.00,δ= 0.00 or 0.25) was conducted to understand the origin of resistance switching by doping.
A weight averaged approach for predicting amide vibrational bands of a sphingomyelin bilayer
Authors: Yagi Kiyoshi , Li Pai-Chi , Shirota Koichiro , Kobayashi Toshihide , Sugita Yuji
Published: October 2015

A new method is proposed, which combines molecular dynamics and vibrational structure calculations, to calculate the spectra of a sphingomyelin bilayer.
Thermoelectricity in polymer composites due to fluctuation-induced tunneling
Authors: Stedman T. , Wei K. , Nolas G. S. , Woods L. M.
Published: October 2015

Thermally induced fluctuations tunneling between localized conducting regions is an important mechanism for transport properties in highly doped polymers.
Controllable synthesis of 3D BiVO4 superstructures with visible-light-induced photocatalytic oxidation of NO in the gas phase and mechanistic analysis
Authors: Ou Man , Nie Haoyu , Zhong Qin , Zhang Shule , Zhong Lei
Published: October 2015

Three 3D ms-BiVO4 superstructures, including a flower, a double-layer half-open flower and a hollow tube with square cross-sections has been synthesized and used for the photocatalytic oxidation of NO. The identification of the main active species in the PCO of the NO process was also clarified.
A proton–electron sequential transfer mechanism: theoretical evidence about its biological relevance
Authors: Muñoz-Rugeles L. , Alvarez-Idaboy J. R.
Published: October 2015

First evidence of a non-coupled, consecutive proton and electron transfer in protein repair reaction.
Composite of K-doped (NH4)2V3O8/graphene as an anode material for sodium-ion batteries
Authors: Liu Xin , Li Zhiwei , Fei Hailong , Wei Mingdeng
Published: October 2015

The K-doped (NH4)2V3O8/graphene electrode exhibited stable cycling and a good rate performance.
Layered phosphorus-like GeP5: a promising anode candidate with high initial coulombic efficiency and large capacity for lithium ion batteries
Authors: Li Wenwu , Li Huiqiao , Lu Zhijuan , Gan Lin , Ke Linbo , Zhai Tianyou , Zhou Haoshen
Published: October 2015

Layer structured GeP5 is firstly developed as an anode material for LIB, it delivers a reversible capacity of 2300 mA h g−1 with a very high initial coulombic efficiency of 95%.
Biological versus mineralogical chromium reduction: potential for reoxidation by manganese oxide
Authors: Butler Elizabeth C. , Chen Lixia , Hansel Colleen M. , Krumholz Lee R. , Elwood Madden Andrew S. , Lan Ying
Published: October 2015

Abiotic reduction of Cr(vi) by FeS and reduced nontronite led to precipitates that released significant Cr(vi) when exposed to birnessite.
A quantitative microbial risk assessment of wastewater treatment plant blending: case study in San Francisco Bay
Authors: Seto Edmund Y. , Konnan Jon , Olivieri Adam W. , Danielson Richard E. , Gray Donald M. D.
Published: October 2015

Quantitative Microbial Risk Assessment (QMRA) to assess health risk associated with increasing extreme rainfall events and the practice of wastewater blending.
Supported copper catalysts for highly efficient hydrogenation of biomass-derived levulinic acid and γ-valerolactone
Authors: Xu Qing , Li Xinglong , Pan Tao , Yu Chuguo , Deng Jin , Guo Qingxiang , Fu Yao
Published: October 2015

Direct conversion of cellulose-derived levulinic acid into γ-valerolactone and γ-valerolactone into 1,4-pentanediol was carried out by chemoselective hydrogenation catalyzed through supported copper-catalysts.
Synergistic enzymatic and microbial lignin conversion
Authors: Zhao Cheng , Xie Shangxian , Pu Yunqiao , Zhang Rui , Huang Fang , Ragauskas Arthur J. , Yuan Joshua S.
Published: October 2015

The utilization of lignin for fungible fuels and chemicals represents one of the most imminent challenges in modern biorefineries.
A structural model for multimodular NRPS assembly lines
Authors: Marahiel Mohamed A.
Published: October 2015

This viewpoint article focuses on the structures of the dissected catalytic domains of non-ribosomal peptide synthetases and how these structural details of the NRPS machinery, integrated in a didomain and an elongation module were used to generate a model for a multimodular NRPS assembly line.
The role of the cell cycle in the cellular uptake of folate-modified poly(l-amino acid) micelles in a cell population
Authors: Tang Jihui , Liu Ziwei , Ji Fenqi , Li Yao , Liu Junjie , Song Jian , Li Jun , Zhou Jianping
Published: October 2015

Nanoparticles are widely recognized as a vehicle for tumor-targeted therapies.
Magnetic bead-quantum dot assay for detection of a biomarker for traumatic brain injury
Authors: Kim Chloe , Searson Peter C.
Published: October 2015

Magnetic bead-quantum dot assay for detection of S100B.
Bi-phasic titanium dioxide nanoparticles doped with nitrogen and neodymium for enhanced photocatalysis
Authors: Gomez Virginia , Bear Joseph C. , McNaughter Paul D. , McGettrick James D. , Watson Trystan , Charbonneau Cecile , O'Brien Paul , Barron Andrew R. , Dunnill Charles W.
Published: October 2015

Bi-phasic or multi-phasic composite nanoparticles for use in photocatalysis have been produced by a new synthetic approach.
Decarboxylative substitution of β-keto acids to benzylic alcohols catalyzed by molecular iodine
Authors: Han Fuzhong , Zhang Xinxin , Hu Minggang , Jia Lina
Published: October 2015

An efficient method for molecular iodine catalyzed decarboxylative substitution of β-keto acids with benzylic alcohols has been described.
Cu(ii)-catalyzed enantioselective oxygen atom transfer from oxaziridine to oxindole derivatives with chiral phenanthroline
Authors: Naganawa Yuki , Aoyama Tomotaka , Nishiyama Hisao
Published: October 2015

In the presence of a Cu(ii) complex of chiral, N,N,O-tridentate phenanthroline ligand (S)-2, asymmetric oxygen atom transfer of oxindole (3) using Davis’ oxaziridine (4) occurred to give the corresponding 3-aryl-3-hydroxy-2-oxindole derivatives (1) with excellent enantioselectivity.
Divergent and convergent synthesis of GalNAc-conjugated dendrimers using dual orthogonal ligations
Authors: Thomas Baptiste , Pifferi Carlo , Daskhan Gour Chand , Fiore Michele , Berthet Nathalie , Renaudet Olivier
Published: October 2015

We report a synthetic strategy to prepare hexadecavalent glycodendrimers that can be used in both divergent and convergent route with similar efficiency.
MoS2/reduced graphene oxide hybrid structure and its tribological properties
Authors: Zhang Mingsuo , Chen Beibei , Yang Jin , Zhang Hongmei , Zhang Qing , Tang Hua , Li Changsheng
Published: October 2015

(a) TEM image of MoS2/RGO hybrid material; variations of friction coefficients of different solid lubricants at (b) room temperature and (c) 600 °C.
Relationship between diffusion of Co3+/Co2+ redox species in nanopores of porous titania stained with dye molecules, dye molecular structures, and photovoltaic performances
Authors: Kawano Minobu , Nishiyama Tsubasa , Ogomi Yuhei , Pandey Shyam S. , Ma Tingli , Hayase Shuzi
Published: October 2015

Diffusion of Co2+ and Co3+ in nanopores of porous titania stained with dyes were evaluated. Voc was obtained for the DSSC with fast Co3+ diffusion in nanopores. After staining with long alkyl groups, the efficiency increased from 2.8% to 5.3%.
Passivation effect of graphene on AlGaN/GaN Schottky diode
Authors: Shen Lingyan , Cheng Xinhong , Wang Zhongjian , Xia Chao , Cao Duo , Zheng Li , Wang Qian , Yu Yuehui
Published: October 2015

Monolayer graphene was used as a passivation layer on a AlGaN/GaN diode to reduce surface leakage current and increase flat-band voltage.
Growth responses and accumulation of cadmium in switchgrass (Panicumvirgatum L.) and prairie cordgrass (Spartinapectinata Link)
Authors: Zhang Chaolan , Guo Jia , Lee D. K. , Anderson Eric , Huang He
Published: October 2015

Phytoextraction could be an efficient technique to remediate heavy metals from contaminated soils.
Hyperbranched polyethylenimine-based sensor of multiple metal ions (Cu2+, Co2+and Fe2+): colorimetric sensing via coordination or AgNP formation
Authors: Vinod Kumar V. , Thenmozhi M. K. , Ganesan Asaithampi , Ganesan S. Selva , Anthony Savarimuthu Philip
Published: October 2015

A commercially available HPEI polymer has been used as a single colorimetric probe for the selective colorimetric sensing of multiple metal ions in aqueous solution with distinguishable colors.
Controlled covalent binding of antiferromagnetic tetramanganese complexes to carbon nanotubes
Authors: Frielinghaus R. , Besson C. , Houben L. , Saelhoff A.-K. , Schneider C. M. , Meyer C.
Published: October 2015

Tetramanganese complexes are covalently attached to carbon nanotubes such, that the magnetic properties of the antiferromagnetic molecules are preserved.
A reversible molecule-gated system using mesoporous silica nanoparticles functionalized with K+-stabilized G-rich quadruplex DNA
Authors: Yang Xue , He Dinggeng , Cao Jie , He Xiaoxiao , Wang Kemin , Zou Zhen
Published: October 2015

A novel and reversible molecule-gated system consisting of mesoporous silica nanoparticles (MSN) functionalized on the pore outlets with a G-rich quadruplex DNA was designed for on-demand molecular transport.
Pressure-sensitive adhesives based on tung oil
Authors: Li Anlong , Li Kaichang
Published: October 2015

A new class of pressure-sensitive adhesives was developed from renewable tung oil in this study.
Biodegradable oligo (poly-l-lysine) as a high-performance hydration inhibitor for shale
Authors: Xuan Yang , Jiang Guancheng , Li Yingying , Yang Lili , Zhang Xianmin
Published: October 2015

Oligo (poly-l-lysine) (OPLL), utilized as a high-performance inhibitor for the hydration of shale, was synthesized with l-lysine as a monomer by the thermal copolymerization method.
Nanoparticle size influences the proliferative responses of lymphocyte subpopulations
Authors: le Guével Xavier , Palomares Francisca , Torres Maria J. , Blanca Miguel , Fernandez Tahia D. , Mayorga Cristobalina
Published: October 2015

Ultra-small particles (<2 nm) lead to high cellular uptake without DC maturation and therefore lymphocyte proliferation whereas 12 nm gold nanoparticles induce cell mediated responses and accompanied by inflammatory natural killer cell stimulation.
Near-field electrospinning enhances the energy harvesting of hollow PVDF piezoelectric fibers
Authors: Pan Cheng-Tang , Yen Chung-Kun , Wang Shao-Yu , Lai Yan-Cheng , Lin Liwei , Huang J. C. , Kuo Shiao-Wei
Published: October 2015

The power generation of the piezoelectric PVDF fiber tubes was 2.46 times higher than that of the solid fibers, which not only displayed mechanical stiffness but also produced a greater power output.
Enhancement of anammox performance in a novel non-woven fabric membrane bioreactor (nMBR)
Authors: Ren Long-Fei , Liang Shuang , Ngo Huu Hao , Guo Wenshan , Ni Shou-Qing , Liu Cui , Zhao Yuan-Kun , Hira Daisuke
Published: October 2015

As well as a membrane separator, a non-woven fabric module could be employed as a biomass carrier to enhance microorganism proliferation and nitrogen removal.
Cleaning of olive mill wastewaters by visible light activated carbon doped titanium dioxide
Authors: Cuomo Francesca , Venditti Francesco , Ceglie Andrea , De Leonardis Antonella , Macciola Vincenzo , Lopez Francesco
Published: October 2015

Visible light activated carbon doped titanium dioxide fully works in the removal of total phenols from olive mill wastewater.
High-performance flexible dye-sensitized solar cells by using hierarchical anatase TiO2 nanowire arrays
Authors: Chai Zhisheng , Gu Jiuwang , Khan Javid , Yuan Yufei , Du Lianhuan , Yu Xiang , Wu Mingmei , Mai Wenjie
Published: October 2015

Thin, lightweight and flexible dye-sensitized solar cells (DSSCs) using three different kinds of TiO2 nanostructures grown on Ti meshes as photoanodes have been fabricated.
Anti-inflammation and anti-fibrosis with PEGylated, apigenin loaded PLGA nanoparticles in chronic pancreatitis disease
Authors: Feng Wen-ming , Guo Hui-hui , Xue Tao , Wang Xiang , Tang Cheng-wu , Ying Bao , Gong Hui , Cui Ge
Published: October 2015

In this work, apigenin, a drug that can inhibit pancreatic stellate cell fibrosis, is loaded into PEGylated PLGA nanoparticles to treat the inflammation and fibrosis associated with chronic pancreatitis (CP).
Smart rose flower like bioceramic/metal oxide dual layer coating with enhanced anti-bacterial, anti-cancer, anti-corrosive and biocompatible properties for improved orthopedic applications
Authors: Murugan N. , Kavitha L. , Shinyjoy E. , Rajeswari D. , Vimala K. , Kannan S. , Gopi D.
Published: October 2015

The flower like Se,Mn-HAP/ZrO2 dual layer coating on AZ91 magnesium alloy satisfies the requirements in bone cancer treatment and signifies progress in the field of implant materials.
An efficient desulfitative C–C cross coupling of fused thiazolidine-2-thione with boronic acids and boronic acid pinacol esters: formation of fused thiazoles
Authors: Rajaguru Kandasamy , Mariappan Arumugam , Manjusri Ramachandran , Muthusubramanian Shanmugam , Bhuvanesh Nattamai
Published: October 2015

An efficient Pd(0)-catalyzed Cu(i)-mediated desulfitative C–C cross-coupling of benzo-fused thiazolidine-2-thione with boronic acids under neutral conditions and boronic acid pinacol esters under basic conditions has been demonstrated.
Multistep energy and electron transfer processes in novel rotaxane donor–acceptor hybrids generating microsecond-lived charge separated states
Authors: Kirner Sabrina V. , Henkel Christian , Guldi Dirk M. , Megiatto Jr Jackson D. , Schuster David I.
Published: October 2015

A new set of [Cu(phen)2]+ based rotaxanes, featuring [60]-fullerene as an electron acceptor and a variety of electron donating moieties, namely zinc porphyrin (ZnP), zinc phthalocyanine (ZnPc) and ferrocene (Fc), has been synthesized and fully characterized.
Wetting films of aqueous solutions of Silwet L-77 on a hydrophobic surface
Authors: Ivanova N. A. , Kovalchuk N. M. , Sobolev V. D. , Starov V. M.
Published: October 2015

Long-time multilayer films structured within the wetting film at concentration 0.1 wt%. 1, 2, 3, and 4 represent the dark spots appearing on the film.
Efficient visible light-induced photoelectrocatalytic hydrogen production using CdS sensitized TiO2 nanorods on TiO2 nanotube arrays
Authors: Yu Jiangdong , Gong Cheng , Wu Zhi , Wu Yongneng , Xiao Wang , Su Yufeng , Sun Lan , Lin Changjian
Published: October 2015

CdS/TNRs/TNTs were synthesized by combining a hydrothermal method with a sequential-chemical bath deposition method and displayed enhanced visible light-induced photoelectrocatalytic hydrogen production activity compared with TNTs, TNRs/TNTs and CdS/TNTs.
Influence of anionic surface modifiers on the thermal stability and mechanical properties of layered double hydroxide/polypropylene nanocomposites
Authors: Yang Jae-Hun , Zhang Wei , Ryu Hyunju , Lee Ji-Hee , Park Dae-Hwan , Choi J. Yoon , Vinu Ajayan , Elzatahry Ahmed A. , Choy Jin-Ho
Published: October 2015

The thermal stability of PP was significantly improved after the formation of PP nanocomposites with organo-LDH, which was affected by the type of organic modifier in organo-LDH and the loading amount of organo-LDH.
Facile ultrasonic deposition of SnO2nanoparticles on TiO2nanotube films for enhanced photoelectrochemical performances
Authors: Hu Juan , Liu Qing , Zhang Hui , Chen Cheng-Dong , Liang Yan , Du Rong-Gui , Lin Chang-Jian
Published: October 2015

A SnO2–TiO2nanotube composite film applied in photoelectrochemical anticorrosion was fabricated by anodic oxidation combined with facile ultrasonic deposition.
Polymerized ionic liquid block copolymers for electrochemical energy
Authors: Meek Kelly M. , Elabd Yossef A.
Published: October 2015

Polymerized ionic liquid (PIL) block copolymers are an emerging class of polymers that synergistically combine the benefits of both ionic liquids (ILs) and block copolymers into one, where the former possesses a unique set of physiochemical properties and the latter self assembles into a range of nanostructures.
miR-429 regulates alveolar macrophage inflammatory cytokine production and is involved in LPS-induced acute lung injury
Authors: Xiao Ji , Tang Jing , Chen Quan , Tang Dan , Liu Meimei , Luo Min , Wang Yan , Wang Jiazheng , Zhao Zhenyu , Tang Chaoke , Wang Deming , Mo Zhongcheng
Published: October 2015

p38 MAPK (mitogen-activated protein kinase) is a critical regulator in lung inflammation. It can be inactivated by DUSP1 (dual-specificity phosphatase 1) which was identified as a putative target of miR-429. miR-429 mimics directly targeted to the 3′-UTR of the gene encoding DUSP1 may result in the translational attenuation of DUSP1. Moreover, the phosphorylation of p38 MAPK was prolonged after miR-429 mimic treatment. Additionally, miR-429 expression was sensitive to LPS (lipopolysaccharide) stimulation and the miR-429 mimics increased the production of pro-inflammatory cytokines. However, anti-miR-429 reduced the LPS-induced production of pro-inflammatory cytokines. These results provide direct evidence that miR-429 is involved in the LPS-induced inflammatory response. In parallel with miR-429, miR-200b and miR-200c, but not miR-200a or miR-141, shared similar effects. In vivo, LPS induced the expression of miR-429, miR-200b and miR-200c in lung. At the same time, inhibiting these miRNAs by anti-miRNAs attenuated the LPS-induced pulmonary inflammatory response and injury. These findings reveal that miR-429 possesses pro-inflammatory activities and may be a potential therapy target for LPS-induced lung injury.
FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis
Authors: Li Qing , Xie Jing , He Lin , Wang Yuanli , Yang Hongdan , Duan Zelin , Wang Qun
Published: October 2015

Ovarian development in crustaceans is characterized by rapid production of egg yolk protein in a process called vitellogenesis. In the present study, we investigated the involvement of a DEAD (Asp-Glu-Ala-Asp) box RNA helicase 20 (DDX20), forkhead transcription factor (FOXL)2 and fushi tarazu factor (FTZ-F)1 in the regulation of vitellogenesis. Based on ESTs from the testis and accessory gland of Eriocheir sinensis, we cloned the full-length cDNAs of foxl2 and fushitarazu factor 1 (ftz-f1), which include the conserved structural features of the forkhead family and nuclear receptor 5A (NR5A) family respectively. The expression of foxl2 mRNA surged at the mature stage of the ovary, when vtg mRNA swooped, suggesting that foxl2 negatively affects the vitellogenin (VTG) synthesis at this developmental stage. Etoposide (inducing germ cell apoptosis) treatment up-regulated FOXL2 and DDX20 at both the mRNA and the protein levels, primarily in the follicular cells as shown by immunofluorescence analysis. Furthermore, foxl2, ddx20 and ftz-f1 mRNA levels increased significantly with right-eyestalk ablation. Interactions between FOXL2 and DDX20 or FTZ-F1 were confirmed by co-immunoprecipitation and the forkhead domain of FOXL2 was identified as the specific structure interacting with FTZ-F1. In conclusion, FOXL2 down-regulates VTG expression by binding with DDX20 in regulation of follicular cell apoptosis and with FTZ-F1 to repress the synthesis of VTG at the mature stage. This report is the first to describe the molecular mechanism of VTG synthesis in E. sinensis and may shed new light on the regulation of cytochrome P450 enzyme by FOXL2 and FTZ-F1 in vitellogenesis.
Identifying radiotherapy target volumes in brain cancer by image analysis
Authors: Cheng Kun , Montgomery Dean , Feng Yang , Steel Robin , Liao Hanqing , McLaren Duncan B. , Erridge Sara C. , McLaughlin Stephen , Nailon William H.
Published: October 2015

To establish the optimal radiotherapy fields for treating brain cancer patients, the tumour volume is often outlined on magnetic resonance (MR) images, where the tumour is clearly visible, and mapped onto computerised tomography images used for radiotherapy planning. This process requires considerable clinical experience and is time consuming, which will continue to increase as more complex image sequences are used in this process. Here, the potential of image analysis techniques for automatically identifying the radiation target volume on MR images, and thereby assisting clinicians with this difficult task, was investigated. A gradient‐based level set approach was applied on the MR images of five patients with grades II, III and IV malignant cerebral glioma. The relationship between the target volumes produced by image analysis and those produced by a radiation oncologist was also investigated. The contours produced by image analysis were compared with the contours produced by an oncologist and used for treatment. In 93% of cases, the Dice similarity coefficient was found to be between 60 and 80%. This feasibility study demonstrates that image analysis has the potential for automatic outlining in the management of brain cancer patients, however, more testing and validation on a much larger patient cohort is required.
Hierarchical predictive control scheme for distributed energy storage integrated with residential demand and photovoltaic generation
Authors: Lampropoulos Ioannis , Garoufalis Panagiotis , van den Bosch Paul P.J. , Kling Wil L.
Published: October 2015

A hierarchical control scheme is defined for the energy management of a battery energy storage system which is integrated in a low‐voltage distribution grid with residential customers and photovoltaic installations. The scope is the economic optimisation of the integrated system by employing predictive control techniques. The approach is based on hierarchical decomposition of the optimisation problem in the time domain by composing a three‐level scheduling and control scheme, that is, day‐ahead, intra‐hour, and real‐time, where the initial and final states of each sub‐problem are chosen as coordination parameters. The day‐ahead and the intra‐hour problems address the interactions with electricity markets during the scheduling phase. The real‐time algorithm is able to adapt the operation of the battery system according to updated information about market conditions, residential demand, and local generation, and subject to the network capacity and other technical constraints. The simulation scenarios address the interactions with the day‐ahead auction and the imbalance settlement system in the Netherlands.