bluuebunny/crossref_metadata_2025 huggingface dataset:
سلسلة القيمة كمدخل لتعزيز الميزة التنافسية في مؤسسات التعليم العالي- دراسة تحليلية
Authors: الخنبشية خولة بنت خليفة , العمري أيمن أحمد
Published: April 2023

تهدف هذه الدراسة التعرف إلى كيفية استخدام مدخل سلسلة القيمة لتعزيز الميزة التنافسية لمؤسسات التعليم العالي، واعتمدت المنهج الوصفي، والذي من خلاله تم استعراض الميزة التنافسية من حيث النشأة والمفهوم والخصائص والأهمية والاستراتيجيات، وكذلك استعراض مفهوم سلسلة القيمة وأنشطتها، وأهميتها في مؤسسات التعليم العالي، وأبرز النماذج المتعلقة باستخدامها في هذه المؤسسات، وذلك من خلال الإجابة عن الأسئلة الآتية: ما الإطار المفاهيمي والفكري للميزة التنافسية في مؤسسات التعليم العالي؟، وما الإطار المفاهيمي والفكري لسلسلة القيمة وأنشطتها الرئيسة والداعمة؟، وما أبرز النماذج العالمية لسلسلة القيمة المستخدمة لتعزيز الميزة التنافسية في مؤسسات التعليم العالي؟. وقد خلصت نتائج الدراسة إلى ضرورة تبني مدخل سلسلة القيمة من أجل تعزيز الميزة التنافسية لمؤسسات التعليم العالي؛ حتى تتمكن من تحقيق أدوارها والتميز ومواكبة التقدم المستمر، وتحقيق التميز الاستراتيجي على مؤسسات التعليم العالي المنافسة في الخدمات التعليمية والبحثية المقدمة إلى المهتمين لضمان حصة سوقية أكبر، وأوصت الدراسة بتطبيق برامج حديثة لتنمية المهارات الأكاديمية لأعضاء هيئة التدريس من خلال التعاون مع استشاريين متميزين من جامعات أجنبية، كما أوصت بتطوير التشريعات واللوائح الجامعية، وتطوير البنية التحتية للجامعات، والاستثمار والمشاركة في المشاريع الوطنية.
PENGARUH KOMIK ONLINE BERBASIS MEDIA SOSIAL UNTUK SOSIALISASI ANTI NARKOBA TERHADAP KARAKTER SISWA SEKOLAH DASAR
Authors: Irman Rahmy Fadilla , Yuliastrin Adisti , Vebrianto Rian
Published: April 2023

Substance misuse is a problem that frequently arises among teenagers, particularly among pupils in primary school. In elementary school, the teaching focuses primarily on increasing students' knowledge and abilities, with very little attention paid to the students' moral and ethical development. Thus, the erosion of students' moral fiber will result in the country's failure to produce productive citizens in the following generation. The goal of this research was to investigate the influence that reading comics online has on the personalities of elementary students. In this work, experimental research, specifically quasi-experimental research, is used. Researchers use a method called random sampling to decide the sample they will use. Students in grade four of elementary schools served as the population for the sample. The control and experimental classes each had 22 students. This study used a Likert-scale questionnaire. This study endeavor analyzed data using descriptive analysis, normality, paired sample t-tests, and SPSS 16-assisted homogeneity tests. The Sig. (2tailed) value of the paired sample t-test is 0.000<0.05, so Online Comic Learning Media does affect student character. The findings of this study imply that it is reasonable to expect teachers to be able to employ learning media that is both interesting and concrete, as well as to be accompanied by technology; one of the choices is making use of comics
METODE SISTEMATIC LITERATUR RIVIEW UNTUK ANALISIS KESESUAIAN PENGEMBANGAN MEDIA BELAJAR PADA KURIKULUM MERDEKA
Authors: Ramadhan Faisal Arief , Wibowo Yusuf Rendi , Irfan Irfan , Romadhon Kharisma
Published: April 2023

This study aims to assess the appropriateness of learning resources produced with the use of independent, curriculum-based R&D research. This study falls within the qualitative research category since it makes use of phenomenological methods. The data in this study were examined using the data analysis technique known as the systematic literature review, or SLR (SLR). By employing a systematic literature review strategy, where each step is outlined, researchers may methodically scan reviews and locate articles. Researchers must gather and then filter journal articles from Google Scholar, SINTA, DOAJ, and Scopus in order to finish the study. The articles are then gathered and archived between 2021 and 2022 using the year of publication criterion. 216 articles that are closely linked to the keywords used were chosen by the researchers from a range of publications. The researcher's next step is to gather research and development-related papers as part of a research plan to provide educational materials for a self-contained curriculum. The results of this study are utilized to develop the final conclusions of 15 journal articles that may be employed in an autonomous curriculum for learning at the primary school level. 15 educational resource articles are created using the ADDIE paradigm. Video animations, interactive PowerPoint slide shows, comic books, Macro Media Flash, Android applications, and Articulate Storylines are just a few of the eight various instructional media forms that may be used
PENGEMBANGAN MEDIA PEMBELAJARAN MENGGUNAKAN APLIKASI CANVA PADA PEMBELAJARAN TEMATIK TERPADU DI KELAS V SEKOLAH DASAR
Authors: Hafidh Muhenda , Lena Mai Sri
Published: April 2023

This research is motivated by the limited use of attractive and easy-to-understand digital media that can stimulate students in learning. The purpose of this study was to produce learning animated videos using the Canva application for valid and practical integrated thematic learning for class V SD, as well as to determine the validity and practicality of the media being developed. This type of research is development research (R&D). Using a 4D model consisting of several stages (Define, Design, Develop, Dissiminate). This research was only carried out until the development stage (Develop) due to limited time and available funds. The subjects of this study were 3 experts, 1 teacher and 27 students of class V SDN 12 Kampung Durian. The results of research on developing learning media using the Canva application obtained a validity level of 93.75% from the media aspect from the language aspect 95% and from the material aspect 88%. Based on the results of the teacher's response and also the results of the responses of students in research schools in schools it can be seen that learning using learning media the percentage of teacher responses at SDN 12 Kampung durian is 94% while the percentage of student responses is 96.6%. Thus it was concluded that the learning media using the Canva application in integrated thematic learning for class V elementary school had been declared valid and practically used in the learning process. Based on the results of the teacher's response and also the results of the responses of students in research schools in schools it can be seen that learning using learning media the percentage of teacher responses at SDN 12 Kampung durian is 94% while the percentage of student responses is 96.6%. Thus it was concluded that the learning media using the Canva application in integrated thematic learning for class V elementary school had been declared valid and practically used in the learning process. Based on the results of the teacher's response and also the results of the responses of students in research schools in schools it can be seen that learning using learning media the percentage of teacher responses at SDN 12 Kampung durian is 94% while the percentage of student responses is 96.6%. Thus it was concluded that the learning media using the Canva application in integrated thematic learning for class V elementary school had been declared valid and practically used in the learning process
UPAYA PEMERINTAH INDONESIA DALAM MENJAGA KEAMANAN MARITIM
Authors: Arry Prasetyo Kuncoro , Ansori Ansori , Suseto Buddy
Published: April 2023

Dalam rangka membangun tata kelola maritim yang baik, sudahkah pemerintah Indonesia mengutamakan keamanan maritim pada masing-masing kebijakan maritimnya, namun nyatanya gagasan Poros Maritim Dunia yang diterapkan oleh pemerintah Indonesia belum membayangi perspektif keamanan maritim. . Tujuan akhir haruslah pembangunan kekuatan angkatan laut sebagai elemen pendukung terpenting. Tujuan dari penelitian ini adalah untuk  menganalisis pemerintahan Joko Widodo (Jokowi) dalam menangani isu keamanan maritim. Metode penelitian diskriptif kualitatif dan penggunaan datanya adalah data sekunder berupa literature review dan interpretasi yang ditemukan pada artikel jurnal sebelumnya  dengan teknik pengumpulan data menggunakan studi kepustakaan. Hasil penelitian menunjukan bahwa dalam menangani isu keamanan maritim diperlukan upaya pemerintah melalui  pendekatan kers (hard effort) dan pendekatan lunak (soft effort).
Family Affiliation and Electoral Politics in District Charsadda: A Case Study of 2013 General Elections
Authors: Ibrahim Muhammad , Khan Shahbaz , Bashir Nadia
Published: April 2023

This paper explores family affiliation as a determinant in describing voting behaviour in NA-8 Charsadda. The study argues that family affiliation is an important determinant of electoral politics in district Charsadda. In order to predict the electoral consequences of electoral behaviour in the universe, a survey has been conducted using questionnaire as a tool of data collection. In this regard, a sample of 304 respondents has been selected through multistage, random and systematic sampling from the voter list. Analysis has been made via descriptive statistics including frequency distribution and percentage and inferential statistics including the Chi-square test and probability value. The primary data reveal that (67.9%) of the respondents supported the view that the electoral preferences have been made on the basis of family affiliation in district Charsadda in the 2013 general elections.
(De) Constructing The Correlation Between First Language Acquisition And Second Language Learning
Authors: Mirza Ejaz , Shafi Shahzeb , Ahmed Faraz
Published: April 2023

Language acquisition is a significant and captivating hallmark of human development. This review article briefly describes a few hindrances that the learner of English as being second language learner may deal with. It searches out the essential factors which play a significant part in the second language (L2) learning process. There is a common notion that the learning of L2 is affected by the learner’s first language, so we may assert that the mother tongue or first language can interfere with the learning process of L2. The current review showcases the dissimilarities and similarities between L1 and second language acquisition, which is finally concluded with a few implications for language researchers and teachers of English as a Second/ Foreign/ Additional Language.
Growing From Emerging Entrepreneurs into Brands: A Systematic In-depth Literature Review of the Psychological Factors
Authors: Khan Shahzad , Ali Mohammad Daud , Majid Abdul
Published: April 2023

The purpose of the study is to identity and develops a comprehensive construct for the entrepreneurs in Pakistani context. The study has used qualitative review to highlight the reasons of entrepreneurship and issues faced by emerging entrepreneurs in Pakistan. The study intended to investigate the extant literature on Entrepreneurial Opportunity Recognition. The researchers focused on reputed and leading journals in order to contribute in a more objective manner. A comprehend review indicates that not just entrepreneurial factors but also shows how setups are branded. The study also highlights a comprehensive psychological model for quantitative testing. The previous studies only shows the importance and factors of entrepreneurship, however, this study also have highlighted the reasons for branding in emerging entrepreneurship. The study will impact to elaborate clearly on the information's about not only entrepreneurship but also the directions towards branding.
What Drives Cryptocurrency Acceptance? Evidence from Pakistan
Authors: Ashfaq Khurram , Nadeem Hafiz Tassawer , Iftikhar Farhan
Published: May 2023

In this study, the proposed model of acceptance factors of cryptocurrencies was analyzed to recognize user behavioral intention by using; web quality, facilitating conditions, perceived risk, e-WOM, and perceived ease of use with the mediating role of the trust factor. An efficient and effective better arrangement of understanding this unique virtual delusion of the use of cryptocurrencies has become an essential part of the virtual world for each stakeholder. So many deliberations on the regulatory frameworks of cryptocurrencies have taken place among government regulators, financial advisors, tax consultants, politicians, thinkers, economists, and lawmakers, but there is inconclusive evidence on legislation in Pakistan.
Safety and efficacy of the p48 MW and p64 flow modulation devices: a systematic review and meta-analysis
Authors: Vivanco-Suarez Juan , Salem Mohamed M. , Sioutas Georgios S. , Covell Michael M. , Jankowitz Brian T. , Srinivasan Visish M. , Burkhardt Jan-Karl
Published: May 2023

OBJECTIVE

Flow diverters (FDs) have demonstrated increasing safety and efficacy in treating various types of intracranial aneurysms. Although the underlying mechanism of action of all FDs is similar, differences are noted in their intrinsic characteristics, materials, and deployment techniques. The p64 flow modulation device (p64) and the newer p48 movable wire flow modulation device (p48 MW) are not yet available in the US but have been increasingly used mainly in Europe, demonstrating optimistic results. The authors performed a systematic review and meta-analysis of the literature to evaluate the safety and efficacy of the p64 and p48 MW FDs.

METHODS

A literature review (between January 1960 and November 2022) of the PubMed, Scopus, Embase, Web of Science, and Cochrane Central Register of Controlled Trials databases was conducted. The primary efficacy outcome was the proportion of complete angiographic occlusion at last follow-up. Complete occlusion was defined as Raymond-Roy class 1 and O’Kelly-Marotta grade D. The primary safety outcomes were the composite safety rate of ischemic and hemorrhagic events (intra- and postprocedure) and the all-cause mortality rate. Data were analyzed using a random-effects proportions meta-analysis, and statistical heterogeneity was assessed.

RESULTS

Twenty studies with 1781 patients harboring 1957 aneurysms were included in the analysis. Seventeen studies were conducted in Europe. Sixteen studies evaluated the performance of the p64 (MW). Patient ages ranged between 20 and 89 years, and most were female (78.7%). Aneurysm size ranged between 1 and 50 mm. Most aneurysms were unruptured (92.8%) and in the anterior circulation (93.1%). Single antiplatelet therapy pre- and postprocedure was used in 2 studies. Follow-up ranged from 2 to 14.5 months. For the p64 and p48 MW, complete angiographic occlusion rates were 77% (95% CI 68%–85%) and 67% (95% CI 49%–81%), adjunctive coil usage rates were 7% (95% CI 4%–12%) and 4% (95% CI 0%–24%), primary safety composite rates were 2% (95% CI 1%–4%) and 3% (95% CI 1%–11%), and mortality rates were 0.49% (95% CI 0%–1%) and 2% (95% CI 1%–6%), respectively.

CONCLUSIONS

The p64 and p48 MW have primarily been used in Europe thus far. This analysis found that both devices have an acceptable efficacy and favorable safety profile. However, further studies are needed to evaluate the efficacy and safety of prescribing a single antiplatelet regimen after implantation of the newer-generation FDs with antithrombotic coating surface modification.
Flow diverter stent treatment for unruptured supraclinoid segment internal carotid artery aneurysms: a Turkish multicenter study
Authors: Yakar Fatih , Elbir Çağrı , Civlan Serkan , Ülkü Göktuğ , Keskin Emrah , Gel Mehmet Selim , Fesli Ramazan , Daltaban İskender Samet , Bakirarar Batuhan , Aydın Hasan Emre , Kiraz İlker , Çiltemek Nazar , Arici Mustafa , Acar Feridun , Coşkun Mehmet Erdal , Türkoğlu Mehmet Erhan
Published: May 2023

OBJECTIVE

Despite the relatively high success of surgical clipping of supraclinoid segment aneurysms of the internal carotid artery (ICA), flow diverter (FD) stent therapy is becoming increasingly used for these aneurysms. This study aims to evaluate the characteristics of FD placement for unruptured ICA supraclinoid segment aneurysms at 6 different centers with different experience levels in Türkiye.

METHODS

In this retrospective, multicenter study, the authors reviewed the demographic information, aneurysm shape/dimensions (neck, aspect ratio, dome/neck ratio, and maximum diameter), preoperative antiplatelet regimen, FD stent brand, perioperative complications, intervention time, clinical (modified Rankin Scale) and radiological (O’Kelly-Marotta [OKM] grading scale) outcomes, and follow-up time of 54 patients.

RESULTS

A total of 55 interventions for 61 aneurysms (58 supraclinoid ICA aneurysms) were performed in the 54 patients included in the study. The female/male ratio in this population was 44/10, and the mean age was 53.5 ± 13.6 (range 21–82) years. The most common form and location of the aneurysms were saccular 91.4% (53/58) and ophthalmic segment 69% (40/58), respectively. The preferred antiplatelet regimen was acetylsalicylic acid plus ticagrelor 50% (27/54). The overall complication rate was 25.5% (14/55), and the mean follow-up time was 25.76 ± 17.88 months. The successful radiological outcome (OKM grade C or D) rate at the 6-month follow-up was 92.6%. No perioperative complications led to any permanent or transient neurological deficit.

CONCLUSIONS

The results of this first multicenter study evaluating FD stent use for unruptured ICA supraclinoid segment aneurysms showed that FD stent treatment is a feasible method for replacing clipping and coil embolization with manageable complications and a high success rate.
Dolichoectatic vertebrobasilar aneurysms: a systematic review and meta-analysis of management strategies and outcomes
Authors: Bin-Alamer Othman , Qedair Jumanah , Palmisciano Paolo , Mallela Arka N. , Nayar Gautam M. , Lu Victor M. , Labib Mohamed A. , Lang Michael J. , Gross Bradley A. , Langer David J. , Couldwell William T. , Friedlander Robert M. , Abou-Al-Shaar Hussam
Published: May 2023

OBJECTIVE

The aim of this study was to describe the efficacy, clinical outcomes, and complications of open cerebrovascular surgery, endovascular surgery, and conservative management of dolichoectatic vertebrobasilar aneurysms (DVBAs).

METHODS

Relevant articles were retrieved from PubMed, Scopus, Web of Science, and Cochrane databases according to PRISMA guidelines. A meta-analysis was conducted for clinical presentation, treatment protocols, and clinical outcomes—good (improved or stable clinical status) or poor (deteriorated clinical status or death)—and mortality rates.

RESULTS

The 9 identified articles described 41 cases (27.5%) of open cerebrovascular surgery, 61 endovascular procedures (40.9%), and 47 cases (31.5%) of conservative management for DVBAs. The total cohort had a good outcome rate of 51.9% (95% CI 28.3%–74.6%), a poor outcome rate of 45.5% (95% CI 23.0%–70.1%), and a mortality rate of 22.3% (95% CI 11.8%–38.0%). The treatment groups had comparable good clinical outcome rates (open cerebrovascular surgery group: 24.7% [95% CI 2.9%–78.2%]; endovascular surgery group: 69.0% [95% CI 28.7%–92.5%]; conservative management group: 57.7% [95% CI 13.0%–92.5%]; p = 0.19) and poor outcome rates (open vascular surgery group: 75.3% [95% CI 21.8%–97.1%]; endovascular surgery group: 27.2% [95% CI 5.6%–0.70.2%]; conservative management group: 39.9% [95% CI 9.1%–81.6%]; p = 0.15). The treatment groups also had comparable mortality rates (open vascular surgery group: 39.5% [95% CI 11.4%–76.8%]; endovascular surgery group: 15.8% [95% CI 4.4%–43.0%]; conservative management group: 19.2% [95% CI 6.8%–43.5%]; p = 0.23).

CONCLUSIONS

The current study of DVBAs illustrated poor outcomes and high mortality rates regardless of the treatment modality. The subgroup analysis showed heterogeneity among the subgroups and advice for personalized management.
An Olive Agenda for Putting Economic and Ecological Justice at the Heart of Faith
Authors: Jong Thandi Soko-de
Published: April 2023

This paper focuses on an “olive agenda” for putting economic and ecological justice at the heart of faith. For many communities in Southern Africa, nature is defined as “that which is created” and “everything in it, is the environment”. This perspective contrasts with many of the lived realities today, where nature is seen less as being summed up in God’s creation and sustenance and is instead regarded more as something to be consumed and used for its benefits. This paper draws from Ekari Mbvundula’s Montague’s Last to argue for economic and ecological justice in dialogue with Steve De Gruchy’s notion of an olive agenda to argue for sustainable, economic and ecological justice. (Chichewa Translation) Mu nkhaniyi tiunikira za chuma, zachilengedwe, komanso chikhristu malingana ndi Ndondomeko yotchedwa “olive agenda”. M’madera ambiri a kumwera kwa Africa, mau akuti "zachilengedwe" amatanthauza "chilichonse chimene chinalengedwa (ndi Namalenga)". Kutanthauzira kotereku kumatsutsana ndi zimene zikuchitika masiku ano, pamene chilengedwe chikuonongeka mu njira zosiyanasiyana chifukwa choti chimawonedwa ngati choyenera kuchigwiritsa ntchito malinga ndi zofuna za anthu. Mu nkhaniyi, tiunikira mfundo zingapo zochokera mu (a) buku la Ekari Mbvundula lotchedwa Montague’s Last ndi (b) ndondomeko ya olive agenda ya Steve De Gruchy. Mfundo zimenezi ziunikira m’mene tingayang’anire zachuma ndi zachilengedwe moyenera.
EFEKTIVITAS EDIBLE COATING DARI PATI SINGKONG TERHADAP SUSUT BOBOT DAN DAYA SIMPAN BUAH DUKU (LANSIUM DOMESTICUM)
Authors: Tarihoran Alex Sandro , Adriadi Ade , Anggraini Juni Harlin , Purba Citra Amelia
Published: April 2023

Penelitian ini bertujuan untuk mengetahui efektivitas edible coating dari pati singkong terhadap susut bobot dan daya simpan buah duku (Lansium domesticum).  Sampel penelitian ini adalah buah duku (Lansium domesticum). Metode yang digunakan dalam penelitian ini adalah metode eksperimen dengan model rancangan yang digunakan pada penelitian ini adalah model Rancangan Acak Lengkap (RAL) non faktorial, yang terdiri dari 4 taraf dengan 3 kali ulangan. Berdasarkan hasil uji ANNOVA pada susut bobot yang telah dilakukan didapatkan hasil pemberian perlakuan edible coating dari pati singkong dengan kombinasi ekstrak lengkuas merah memberikan pengaruh yang sangat nyata/memberikan perbedaan yang sangat nyata terhadap kualitas (susut bobot) buah duku.
Northern Russian intonation: Prosodic breaks
Authors: Knyazev Sergey
Published: May 2023

This paper analyzes prosodic phrasing in Northern Russian dialects spoken in the Pinezhsky, Plesetsky, Verkhnetoemsky, Mezensky, Leshukonsky, Konoshsky, and Vinogradovsky districts of Arkhangelsk Oblast based on the material of dialectal speech corpora and the author’s tape recordings of dialectal speech made in 1987–1999 (49 hours in total). It deals primarily with the issues related to the local markers of prosodic phrasing, their hierarchy and phonetic means of realization. Based on the performed analysis, I suggest the following break index scale in Arkhangelsk dialects: 0 — break index showing strongest cohesion (absence of prosodic break), typical of boundaries internal to prosodic words (e.g., boundaries between clitics and hosts); 1 — break index marking prosodic word boundaries: marked on the right edge of a prosodic word followed by another prosodic word within the same accentual phrase (by means of reset of the word’s rhythmical structure); 2 — break index marking accentual phrase boundaries: marked on the right edge of an accentual phrase followed by another accentual phrase within the same intermediate phrase (phonetically manifested as a signifi cant — more than 1.5 semitones — tonal drop on a voiced consonant and/or on a poststressed vowel); 3 — break index marking a boundary between an intermediate phrase with nuclear pitch accent and an accentual phrase with non-nuclear pitch accent within the same intonational phrase (using a long, 300–1500 ms, interruption in articulation and high or low boundary tone); 4 — break index marking intermediate phrase boundaries: marked on the right edge of an intonational phrase (by means of high or low boundary tone and an optional pause); 5 — break index marking intonational phrase boundaries: marked on the right edge of an intonational phrase (by means of low boundary tone and an optional pause). The most characteristic features of Arkhangelsk dialects from the perspective of prosodic phrasing are 1) the accomodationof microprosodic features (tonal drop on voiced consonants) for macroprosodic purposes (marking accentual phrase boundaries); 2) the use of lasting physical breaks in articulation to mark prosodic phrasing within an intonational phrase; 3) the absence of a sraightforward correlation between the pause duration and the depth of prosodic breaks.
Gender variation and gender markedness in Russian nouns
Authors: Magomedova Varvara
Published: May 2023

In this paper, we analyze diff erent factors aff ecting gender assignment in Russian nouns. We conducted two studies combining experimental, dictionary, and corpus data (relying both on traditional corpora and on the web-as-a-corpus approach). The fi rst study is dedicated to gender assignment to expressive nouns in a situation when the gender of the base noun and the expressive suffix give contradictory cues. We demonstrated extensive gender variation in these cases and estimated the role of different factors affecting it. The gender of the base noun and the inflection associated with the expressive suffix appeared to be the most important. Animacy is also relevant (certain options are possible only for nouns denoting people) but statistically insignifi cant. The second study is on gender assignment to nouns that have a zero inflection in nominative singular and a palatalized, alveolo-palatal, or postalveolar stem-final consonant. In the previous studies, it was noted that the phonological properties of this consonant affect the gender distribution in these nouns. Our data confirmed this generalization and provided several new insights. We also demonstrated that native Russian speakers are sensitive to it. We discuss the implications of our results for different approaches in theoretical morphology and focus on gender markedness analyzing a special status of masculine gender.
[PJK)] : PJK (Penyakit Jantung Koroner) VS SKA (Sindrome Kororner Akut) Prespektif Epidemiologi
Authors: Wahidah Wahidah , Harahap Reni Agustina
Published: April 2023

Penyakit jantung koroner (PJK) yaitu penyakit yang timbul akibat terdapat Flak menumpuk di dalam arteri koroner yang mensuplai oksigen ke otot jantung. Penyakit jantung koroner dengan Sindrome akut memiliki gejala hampir sama akan tetapi ada beberapa gejala yang berbeda. perbedaan dari kedua penyakit ini seperti iskemia dan merasakan rasa tidak nyaman di bagian dada. Rasa tidak nyama pada PJK terjadi secara tiba-tiba namun SKA terjadi pada waktu istirahat. Kedua penyakit ini terjadi pada pria umur 45 tahun tetapi pada wanita >55 tahun. SKA bisa terjadi pada wanita dengan status penyandang hipertensi dan merokok. PJK dan SKA merupakan penyebab kematian di dunia. Kedua penyakit ini seringkali dianggap penyakit yang sama namun memiliki penyebab yang berbeda dan perlu dilakukan analisis perbedaan dari keduanya.
Studi Awal Pajanan Personal Active Pharmaceutical Ingredients (API) Prednisolone pada Pekerja PT. XY
Authors: DEFRIANDI MIRZA , DONI HIKMAT RAMDHAN
Published: April 2023

Abstrak

Sektor industri farmasi merupakan bidang industri penting yang menghasilkan obat-obatan untuk memenuhi kebutuhan pasien serta selalu memastikan keselamatan pasien dalam mengkonsumsi produknya. Akan tetapi pajanan terhadap API (Active Pharmaceutical Ingredients) pada pekerja masih sangat sedikit dilakukan penelitian dan dapat memberikan dampak Kesehatan pada pekerja. Tujuan dari penelitian ini untuk mengetahui apakah pekerja yang terlibat dalam proses pembuatan tablet obat Prednisolone yang termasuk OHC (Occupational Hazard Category) 4 berpotensi terpajan bahan aktif farmasi dan melakukan mengumpulkan data pajanan pekerjaan di fasilitas produksi obat sediaan padat.

Penelitian ini dilakukan dengan mengukur pajanan debu pada pekerja dibagian MPF (Multi Product Facility), yang dimulai dari proses penimbangan, pengayakan, granulasi, cetak tablet dan pengemasan primer. Banyaknya sampel yang diambil berdasarkan jumlah pekerja pada masing-masing proses masing-masing 3 sampel.  Total 15 sampel diuji oleh laboratorium eksternal yang selanjutnya hasil uji dibandingkan dengan OEL (Occupational Exposure Limit) dari Prednisolone yaitu sebesar 9 µg/m3.

Hasil Penelitian menunjukkan pajanan API di lokasi produksi ini bervariasi mulai 0.89 µg/m3 sampai 182.81 µg/m3. Pekerja di bagian proses penimbangan beresiko sangat tinggi terpajan serta pekerja di bagian pengayakan, granulasi dan cetak tablet.

Disimpulkan bahwa pekerja di bagian pembuatan obat tablet pada bagian MPF beresiko terpajan bahan aktif farmasi yang disebabkan karena beberapa tahapan proses dilakukan secara manual dan sistem terbuka, sehingga perlu dilakukan tindakan pengendalian dan perbaikan secara komprehensif untuk melindungi pekerja.

 

Kata kunci: Active Pharmaceutical Ingredients (API), Occupational Hazard Category (OHC), Occupational Exposure Limit (OEL), Prednisololone.
Fishing Rods for Magic: Theatre Forum Tools to Support Primary School Students’ Active Engagement in Computer-Supported Collaborative Storytelling
Authors: Lambropoulos Niki
Published: May 2023

Due to the increasing conflict and complexity on a global level, our students, as future citizens, must develop a new life, soft and transversal skills and competences, and the 4Cs+D (creativity, communication, collaboration, critical thinking + digital skills) for formal and non-formal learning. Creative Storytelling supports students to externalize and communicate their thoughts, feelings, and experiences through their own stories. Stories narrative reframing sets them free from their real, stressful environment contributing to self-awareness, and self-esteem. Although there is rich research about storytelling, there are discrepancies in the ways a story can be structured and even evaluated for constructive feedback, especially to primary school students. In Computer-Supported Collaborative Storytelling (CSCS) students are usually invisible and reluctant to participate, especially if they belong to the SEN (Special Educational Needs) group. Thus, this article suggests pedagogical propositions to create an active, aware, and engaging learning community with the needed knowledge, skills, and competences to solve outer and inner problems. The first is the ASEMA Pyramid (Awareness, Sensitivity, Empathy, Motivation, and Activation) methodology which, together with the active participation eyeball and 4Cs+D skills building with message tagging, can advance students’ engagement in active learning. These methods applied to the Hero's Journey and the Hero's Emotional Journey enable the teachers and their students to become more aware of students' processes and needs. Furthermore, these processes can visualise students’ activities and choices with context-aware tools. Therefore, this article also proposes a set of Theatre Forum Tools to shed light on Primary School students’ online learning activities and their discussion in creative storytelling.
Crosslandia daedali POORMAN & MULLINER, 1981 (NUDIBRANCHIA, DENDRONOTOIDEA, SCYLLAEIDAE) ASSOCIATED WITH BROWN ALGAE IN THE COASTAL ZONE FROM THE STATE OF PARAÍBA, NORTHEASTERN BRAZIL
Authors: Pereira Arthur Albuquerque , Ferreira Erly de Lima , Da Silva João Hermínio , Padula Vinícus , Souza J. Weverton S. , Lima Silvio Felipe Barbosa
Published: May 2023

Nudibranchs are marine gastropods with no shell and usually have a beautiful color pattern. The aim of this work was to record the scyllaeid Crosslandia daedali Poorman & Mulliner 1981 associated with brown algae in the coastal zone from the state of Paraíba, northeastern Brazil. One individual of this species was collected in November 2019 at about 0.5 meters in depth in the subtidal zone of Cabo Branco Beach in the city of João Pessoa. Immediately after collection, the scyllaeid was transferred to a container with seawater, photographed still alive and then fixed in 70% alcohol. The individual measured about 15 mm in length, presented a typical orange-brown color pattern and was associated with brown algae of the genus Padina (Class Phaeophyceae). A large gap in knowledge remains on the richness of nudibranchs in coastal ecosystems of northeastern Brazil associated with algae and reef ecosystems, including the state of Paraíba, which needs to be studied due to the degradation of tropical coastal ecosystems.
OZONIZED VEGETABLE OIL AND VETERINARY APPLICATION
Authors: Furtado Gil Dutra
Published: May 2023

Ozone (O3) is a molecule composed of three atoms of oxygen, very unstable, capable of reacting with various substances in the animal organism, giving rise to by-products that will participate in biochemical reactions. Under this reality, O3 has a broad mechanism of action and can be used in various pathologies of animals, being widely used in the treatment of wound healing. O3 is a substance found naturally in the Earth's atmosphere, however, for its therapeutic use, O3 is produced by a medical generator, which, through high-voltage-electrical-discharges, is capable of capturing medical oxygen from a cylinder and disintegrating it. it so that its molecules are reorganized in the form of ozone. Ozone therapy is considered an integrative therapy that is characterized by the application of a mixture of ozone gas and oxygen gas (O2), with a maximum of 5% O3 (CARNEIRO, 2023; DI FILIPPO et al., 2020). Because it has a broad mechanism of action, ozone therapy is effective in several animal pathologies. The purpose of repeated administration of ozone is to create resistance against oxidative stress by stimulating the antioxidant system, therefore, medicinal ozone is considered a prodrug, as its by-products are responsible for biological effects in the patient's body (DE OLIVEIRA et al., 2014; VASCONCELOS et al., 2022). Ozone in its medicinal use has established itself as a promising treatment and prophylaxis for several conditions, mainly due to its broad mechanism of action, with beneficial effects such as immunomodulatory, antimicrobial, anti-inflammatory, analgesic and healing. Allows penetration into the deep layers of the skin, increasing the supply of oxygen to the cells and strengthening the natural protective barrier. When using the product in oil, it should be used by applying a few drops to the affected areas of the skin several times a day and, in accordance with the guidance of the veterinarian, the treated area should be massaged (WILMINK; VAN WEEREN, 2004). The use of O3 is recommended when the patient has itching, skin inflammation, bacterial skin infections, fungal infections, hardened scar tissue, eczema, fissures, gingivitis and ear infections, always following the advice of the veterinarian. The application of ozone in the form of ozonated oil has been reported to be the most effective.
Effect of Acupressure on Anxiety in Older Women Candidate For Extracorporeal Shock Wave Lithotripsy: A Randomized Controlled Clinical Trial
Authors:   Department of Nursing, Faculty of Nursing & Midwifery, Shahed University, Tehran, Iran., Ziaei Azarkhavarani Fariba , Rejeh Nahid ,   Department of Nursing, Faculty of Nursing & Midwifery, Shahed University, Tehran, Iran., Valiani Mahbobeh ,   Department of Midwifery and Reproductive Health, Nursing and Midwifery Care Research Center, Faculty of Nursing, Isfahan University of Medical sciences, Isfahan, Iran., Kazemi Reza ,   Department of Urology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Published: April 2023

Background and Objectives: Most patients experience anxiety during the Extracorporeal Shock Wave Lithotripsy (ESWL). One of the on-pharmacological ways to control anxiety in patients with ESWL is acupressure. This study aims to determine the effect of acupressure on anxiety in older women candidates for ESWL Methods: This randomized controlled clinical trial was conducted on 66 eligible older women candidates for ESWL referred to Ordibehesht Surgical Center in Isfahan, Iran in 2021. They were selected by a continuous sampling method and assigned to the intervention and control groups by the block randomization method. The intervention group received acupressure for 20 minutes, while in the control group, the acupoints were only touched (without applying pressure). Data collection tools were the Spielberger State-Trait Anxiety Inventory and Visual Anxiety Scale, completed 60 minutes before and immediately after the intervention. T-test, chi-square test, and Mann-Whitney U test were used to analyze the data. Results: The two groups were similar in terms of demographic variables. Before the intervention, there was no statistically significant difference between the two groups in anxiety (P> 0.05). After the intervention, the mean severity of anxiety was 3.70±0.77 in the experimental group and 7.36±0.55 in the control group. The mean post-test quality of anxiety was 35.48±5.97 in the intervention group and 61.39±2.42 in the control group. These differences between the two groups were statistically significant (P<0.001). Conclusion: Acupressure is a safe and non-pharmacological intervention that can reduce the anxiety of older women candidates for ESWL.
Cybersecurity of the municipal infrastructure
Authors: Kaliakin S. V. , Onishchenko Yu. M. , Nosov V. V.
Published: May 2023

A modern city is a complex system that requires a unified systematic approach to ensuring public safety, law and order and environmental safety in the face of high levels of both man-made and natural risks. Due to the growing role of information technology in the functioning of a modern city, the threat of cyberattacks on critical municipal infrastructure has increased. The cost of such cyber-attacks can be very high, both for individual victims and for society as a whole. Cyberattacks can lead to the theft of sensitive information, data destruction or the disclosure of personal data. In addition, such attacks can lead to loss of working time and suspension of systems, which can have serious consequences for the city’s viability.

The experience of other countries in protecting critical municipal infrastructure from cyber threats has been studied, analysed and summarised. The impact of the latest information technologies (such as the Internet of Things, artificial intelligence, blockchain) on the development of municipal infrastructure, the use of these technologies to protect critical infrastructure from cyberattacks, their advantages and disadvantages compared to classical security technologies have been considered. Particular attention has been paid to the problems of safe automation of modern city management processes such as automation of traffic control systems, environmental monitoring systems, financial systems, power grids, water and gas supply systems, communication systems, and control systems for wastewater treatment plants. The features of cyber attacks and the use of methods for protecting critical infrastructure in the context of hybrid warfare have been examined. Recommendations for a comprehensive increase in the level of protection of municipal critical infrastructure from cyber threats have been provided, taking into account the latest global trends in cybersecurity.
DAMPAK KEBIJAKAN BELAJAR DARI RUMAH TERHADAP KONDISI PSIKOLOGIS IBU SISWA SEKOLAH DASAR DI KABUPATEN BOJONEGORO
Authors: Wahdani Firda Rizka Rachma , Dela Ardin Septa , Sukmawati Intan
Published: April 2023

The Covid-19 pandemic has had an impact on everyday life. Not only the economic and business sector, the education sector was not spared from the impact of the virus that originated in Wuhan. This study aims to obtain information related to the psychological impact caused by the study from home policy during the Covid-19 pandemic emergency, especially for student mothers. This study uses a quantitative approach to the survey method. The sample in this study were 150 female students from three regions in Bojonegoro Regency. Among them, namely the Sukorejo Superior MINU, Bojonegoro District, Sembung Elementary School, Kapas District, and Nganti III Elementary School, Ngraho District. Based on the results of correlational calculationsProduct Moment with SPSS 25 Version, the value of r is obtainedcountthe BDR Policy Impact variable (X) is 0.773, and rcountthe variable Psychological Condition of Student Mothers (Y) is 1. This figure is greater than rtable0.159, it can be concluded that the two variables have a significant relationship. This contrasts with the results of interviews with the researchers' mothers. They have difficulty guiding their children to study at home. What's more, online learning involves technology that is not mastered by parents.
Social and Economic Security
Authors: Karanina E. V.
Published: May 2023

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A Selection of Surgical Interventions in Pediatric Hydrocephalus
Authors: Musfirah Nurul , Iskandar
Published: April 2023

Introduction: Hydrocephalus is a condition in which the flow of cerebrospinal fluid is disturbed due to an imbalance between production and reabsorption or because there are obstacles along its distribution channel. The most common surgical intervention and standard strategy for treating hydrocephalus in recent years has been the placement of a shunt, particularly a ventriculoperitoneal shunt (VP-Shunt). In addition to shunt placement, endoscopic third ventriculostomy (ETV) and choroid plexus coagulation (CPC) are currently being performed simultaneously, considering that the combination of the two procedures is sufficient to provide maximum results and can even reduce the risk of failure.

Method: The method of literature review is used in this study.The method chosen is preferred reporting items for systematic reviews and meta-analyses (PRISMA), which involves selecting the characteristics of literature through electronic media with database searches through the PubMed and Google Scholar sites. Patients diagnosed with hydrocephalus, both communicative and noncommunicative, with an age of 18 years; surgical intervention with a Vp-shunt; EVT with or without CPC; and a 3-month follow-up were the inclusion criteria.

Result: There were 1,251 samples included in the 10 articles in this study, 7 of these articles had samples with non-communicable hydrocephalus, with the most common etiologies being post-infection and hemorrhage. The selected interventions, both Vp-Shunt and ETV with or without CPC, have a high percentage of success rates, with an average age of intervention in this study of   6 months.

Conclusion: The choice of intervention in cases of hydrocephalus should be based on patient characteristics. Installation of a shunt, ETV, or ETV/CPC may et he first choice based on the etiology of the hydrocephalus, the patient’s age, and a risk assessment that takes into account the complications that may arise from the selected procedure
ПРОБЛЕМИ ТА ПЕРСПЕКТИВИ РОЗВИТКУ ФІНАНСІВ ПУБЛІЧНОГО СЕКТОРУ В УМОВАХ ЄВРОІНТЕГРАЦІЇ
Authors: Гнидюк Інна , Складанюк Марина
Published: May 2023

У статті визначено сутність та структура публічних фінансів та механізм їх дії в бюджеті країни. Розглянуто особливості та сучасні тенденції публічних фінансів України, окреслено їх значний вплив на здатність держави вдало та результативно виконувати свої функції, сприяти економічному розвитку та забезпеченню цілей суспільного добробуту. У статті обґрунтовано актуальність дослідження питань щодо підвищення ефективності методів акумуляції та напрямків використання публічних коштів в Україні. Узагальнено найважливіші аспекти, в яких держава працює з системою публічних фінансів. Визначено основні недоліки та проблеми функціонування системи публічних фінансів. Досліджено основні перешкоди для успішної євроінтеграції. З’ясовано шляхи подолання даних проблем та окреслено основні можливості для подальшої інтеграції з країнами Європи.
СУЧАСНІ СОЦІАЛЬНО-ПОВЕДІНКОВІ ВИКЛИКИ: ВПЛИВ НА ОБЛІКОВО-ПОДАТКОВУ РЕЗУЛЬТАТИВНІСТЬ ПІДПРИЄМСТВ АЕРОКОСМІЧНОЇ ГАЛУЗІ
Authors: Ліхоносова Ганна , Бортнікова Анна
Published: May 2023

Дослідження наводить аналіз сучасних викликів та умов, в яких працює український бізнес під час воєнних дій, та їх вплив на обліково-податкову діяльність. Був проведений аналіз законів та нормативних документів, що розроблені державою для функціонування та поліпшення становища підприємств, що постраждали внаслідок бойових дій. Методологічною основою дослідження стали наукові публікації та монографічні видання, статті журналів та матеріали науково-практичних конференцій. Під час проведення дослідження було використано контент-аналіз наукової періодики; порівняльний критичний аналіз існуючих підходів та методів аналізу фінансової стійкості та податкового навантаження; аналіз господарської діяльності підприємств аерокосмічної галузі; статистичні методи аналізу. Основною гіпотезою дослідження стало припущення можливості відновлення виробничого потенціалу країни за рахунок впровадженні новітніх обліково-податкових технологій цифрової трансформації України, національних проєктів з розвитку підприємництва, платформ цифрової взаємодії для допомоги з релокації бізнесу. На прикладі підприємства, що належить до авіаційної галузі, досліджено вплив соціально-поведінкових викликів на обліково-податкову діяльність цього підприємства, а саме: на розрахунки з бюджетом, величиною прибутку та на розрахунки з оплати праці. Запропоновано заходи щодо покращення стимулювання бізнесу в умовах воєнного стану.
ВИКОРИСТАННЯ МЕТОДИКИ ТАКСОНОМІЧНОГО АНАЛІЗУ ДЛЯ ОЦІНЮВАННЯ РІВНЯ ПРОДОВОЛЬЧОЇ БЕЗПЕКИ УКРАЇНИ
Authors: Страшинська Лариса , Михайлик Ольга
Published: May 2023

У статті доведено практичну цінність застосування спеціальних економіко-математичних методів для проведення процесу оцінювання рівня продовольчої безпеки держави. Запропоновано для спрощеної формалізації розрахунків індексу продовольчої безпеки використати метод таксономії. Запропонований підхід дозволяє оцінити ступінь сукупного впливу факторних ознак на рівень забезпечення продовольчої безпеки держави. Визначено систему індикаторів (множинних ознак) для оцінки інтегрального показника рівня продовольчої безпеки за ретроспективний період з 2015 по 2021 рік, які створюють ваговий (стимулюючий, дестимулюючий) внесок в загальний індекс продовольчої безпеки. Згідно правила проведення таксономічної процедури нормовано індикатори вхідної матриці, визначено координати точки-еталону, визначено «відхилення» між окремими індикаторами та базовою порівняння, розраховано інтегральний (таксономічний) показник рівня продовольчої безпеки України.
МЕТОДИ ВИЗНАЧЕННЯ НОРМИ ПРИБУТКУ ЯК ОСНОВНОГО КОМПОНЕНТУ ПРОЕКТНОГО АНАЛІЗУ ДІЯЛЬНОСТІ ПІДПРИЄМСТВА
Authors: Ткачук Віталій
Published: May 2023

В умовах глобальних змін та ведення військового стану, що спричинило цілий ряд викликів для економіки держава та для підприємства зокрема, підприємство все-таки повинне прагнути якщо не до одержання максимального прибутку, то принаймні до того обсягу прибутку, що дозволяв би йому не тільки міцно утримувати свої позиції на ринку збуту товарів і надання послуг, але і забезпечувати динамічний розвиток його виробництва в умовах кризовий явищ та конкуренції. В основі своєї діяльності підприємство ставить прибутковість, оскільки отримання якого є запорукою та основною метою ведення будь-якої підприємницької діяльності. Прибуток є орієнтиром економічної діяльності підприємства та показником його логічної доцільності, отже прибутковість підприємства є одним з найголовніших показників, що відображають фінансовий стан підприємства та визначають мету підприємницької діяльності. Тому кожен підприємець повинен мати обґрунтовану стратегію щодо забезпечення прибутковості свого підприємства В остаточному підсумку це потребує від керівництва володіння теоретичними та практичними навичками по аналізу прибутковості підприємства та резервів її підвищення, знання джерел формування прибутку і методів по кращому їхньому використанню, вміння бачити довгострокову перспективу і в результаті цих вмінь формувати місію підприємства та направляти діяльність до її досягнення. Завдання нашого дослідження показати основні елементи ведення підприємницької діяльності в спектрі його можливих прибутків з економічної доцільності, де прибуток є запорукою усього ведення проекту підприємницької діяльності та окупності вкладених витрат.