bluuebunny/crossref_metadata_2025 huggingface dataset:
Muscular heat shock protein response and muscle damage after semi‐professional football match
Authors: Wiig Håvard , Cumming Kristoffer T. , Handegaard Vilde , Stabell Jostein , Spencer Matthew , Raastad Truls
Published: March 2022

Purpose

A typical football match leads to neuromuscular fatigue and physical performance impairments up to 72–96 h post‐match. While muscle damage is thought to be a major factor, damage on the ultrastructural level has never been documented. The purpose of this study was to investigate post‐match cellular muscle damage by quantifying the heat shock protein (HSP) response as a proxy for protein damage.

Methods

Muscle biopsies, blood samples, countermovement jumps, and perception of muscle soreness were obtained from twelve semi‐professional football players 1, 24, 48, and 72 h after a 90‐min football match. Muscle biopsies were analyzed for αB‐crystallin and HSP70 in the cytosolic and cytoskeletal sub‐cellular fractions by Western blotting. Fiber type‐specific αB‐crystallin and HSP70 staining intensity, and tenascin‐C immunoreactivity were analyzed with immunohistochemistry. Blood samples were analyzed for creatine kinase and myoglobin.

Results

Within 24 h post‐match, a 2.7‐ and 9.9‐fold increase in creatine kinase and myoglobin were observed, countermovement jump performance decreased by −9.7% and muscle soreness increased by 0.68 units. αB‐crystallin and HSP70 accumulated in cytoskeletal structures evident by a 3.6‐ and 1.8‐fold increase in the cytoskeletal fraction and a parallel decrease in the cytosolic fraction. In type I and II fibers, αB‐crystallin staining intensity increased by 15%–41% and remained elevated at 72 h post‐match. Lastly, the percentage of fibers with granular staining of αB‐crystallin increased 2.2‐fold.

Conclusions

Football match play induced a muscular HSP stress response 1–72 h post‐match. Specifically, the accumulation of HSPs in cytoskeletal structures and the granular staining of αB‐crystallin suggests occurrence of ultrastructural damage. The damage, indicated by the HSP response, might be one reason for the typically 72 h decrease in force‐generating capacity after football matches.
Time spent walking and disability‐free survival in older Japanese: The Ohsaki Cohort 2006 Study
Authors: Ito Kumiko , Tomata Yasutake , Obuchi Shuichi , Kawai Hisashi , Zhang Shu , Sone Toshimasa , Sugawara Yumi , Tsuji Ichiro
Published: March 2022

The extent to which long disability‐free survival (DFS) time can be extended according to the amount of time spent walking has not been investigated. The aim of this study was to examine the association between time spent walking per day and DFS time in older adults. We conducted a cohort study of 14 342 disability‐free individuals (aged ≥ 65 years) living in Ohsaki City, Japan. The amount of time spent walking per day (<0.5 h, 0.5–1 h, ≥1 h) by each individual in 2006 was assessed by a self‐reported questionnaire. Data on 11‐year incident functional disability were retrieved from the public Long‐Term Care Insurance database. After estimating the multivariable‐adjusted hazard ratios (HRs) of the composite outcome (incident functional disability or death), the multivariable‐adjusted 50th percentile differences (50th PDs; difference in the period until the first 50% of the composite outcome occurred) were estimated according to time spent walking. Among 114 764 person‐years, the composite outcome occurred in 7761 persons (67.6 per 1000 person‐years). The HRs (95% confidence intervals) of the composite outcome were 1.00 (reference) for <0.5 h, 0.84 (0.79, 0.88) for 0.5–1 h, and 0.78 (0.74, 0.83) for ≥1 h (p‐trend < 0.001). The 50th PDs (95% confidence intervals) of DFS time were 238 (155, 322) days longer for 0.5–1 h and 360 (265, 454) days longer for ≥1 h, in comparison with <0.5 h. The results suggest that longer time spent walking per day contributes to longer DFS time.
Fifty years of welfare state generosity
Authors: Scruggs Lyle A. , Ramalho Tafoya Gabriela
Published: March 2022

This article describes an overview of key findings from the Comparative Welfare Entitlements Project (CWEP). CWEP compiles major features of the generosity of unemployment, sickness and public pension programs over the last several decades in 21 countries. Describing and extending earlier work to measure the institutional variation in major social insurance programs over time, we provide previously unpublished methodological details of widely used measures of program generosity; measures which have appeared in over 200 analyses during the last decade and a half. We find a high level of variation in wage replacement and benefit conditionality across programs in most countries; calling into question the notion of an historically stable configurations of characteristics, at least during the last 45 years. For instance, our research shows that several prototypical social democratic welfare states experienced the highest declines in generosity in the last three decades. Furthermore, we also show that, as late as the mid‐1970s, some ‘social democratic’ welfare states still trailed some ‘conservative’ welfare states, including prototypical ones like Germany.
Association between gut colonization of vancomycin‐resistant enterococci and liver transplant outcomes
Authors: Chiang Diana , Dingle Tanis C. , Belga Sara , Kabbani Dima , Bhanji Rahima A. , Walter Jens , Abraldes Juan G. , Cervera Carlos
Published: March 2022

Background

Vancomycin‐resistant enterococci (VRE) colonization is common in liver transplant recipients and has been associated with worse posttransplant outcomes.

Methods

We conducted a retrospective cohort study at the University of Alberta Hospital including patients who underwent a liver transplant between September 2014 and December 2017.

Results

Of 343 patients, 68 (19.8%) had pretransplant VRE colonization and 27 (27/275, 9.8%) acquired VRE posttransplant, 67% were males and the median age was 56.5 years. VRE colonized patients at baseline had higher MELD scores and required longer posttransplant hospitalization. VRE colonization was associated with increased risk of early acute kidney injury (AKI) (64% vs. 52%, p = .044), clinically significant bacterial/fungal infection (29% vs. 17%, p = .012) and invasive VRE infection (5% vs. 1%, p = .017). Mortality at 2 years was 13% in VRE‐colonized versus 7% in noncolonized (p = .085). On multivariate analysis, VRE colonization increased the risk of posttransplant AKI (HR 1.504, 95% CI: 1.077‐2.100, p = .017) and clinically significant bacterial or fungal infection at 6 months (HR 2.038, 95% CI: 1.222–3.399, p = .006), and was associated with nonsignificant trend toward increased risk of mortality at 2 years posttransplant (HR 1.974 95% CI 0.890–4.378; p = .094).

image

Conclusions

VRE colonization in liver transplant patients is associated with increased risk of early AKI, clinically significant infections, and a trend toward increased mortality at 2 years.
AtGH3.10 is another jasmonic acid‐amido synthetase in Arabidopsis thaliana
Authors: Delfin Jay C. , Kanno Yuri , Seo Mitsunori , Kitaoka Naoki , Matsuura Hideyuki , Tohge Takayuki , Shimizu Takafumi
Published: March 2022

Jasmonoyl‐isoleucine (JA‐Ile) is a key signaling molecule that activates jasmonate‐regulated flower development and the wound stress response. For years, JASMONATE RESISTANT1 (JAR1) has been the sole jasmonoyl‐amino acid synthetase known to conjugate jasmonic acid (JA) to isoleucine, and the source of persisting JA‐Ile in jar1 knockout mutants has remained elusive until now. Here we demonstrate through recombinant enzyme assays and loss‐of‐function mutant analyses that AtGH3.10 functions as a JA‐amido synthetase. Recombinant AtGH3.10 could conjugate JA to isoleucine, alanine, leucine, methionine, and valine. The JA‐Ile accumulation in the gh3.10–2 jar1‐11 double mutant was nearly eliminated in the leaves and flower buds while its catabolism derivative 12OH‐JA‐Ile was undetected in the flower buds and unwounded leaves. Residual levels of JA‐Ile, JA‐Ala, and JA‐Val were nonetheless detected in gh3.10–2 jar1‐11, suggesting the activities of similar promiscuous enzymes. Upon wounding, the accumulation of JA‐Ile and 12OH‐JA‐Ile and the expression of JA‐responsive genes OXOPHYTODIENOIC ACID REDUCTASE3 and JASMONATE ZIM‐DOMAIN1 observed in WT, gh3.10–1, and jar1‐11 leaves were effectively abolished in gh3.10–2 jar1‐11. Additionally, an increased proportion of undeveloped siliques associated with retarded stamen development was observed in gh3.10–2 jar1‐11. These findings conclusively show that AtGH3.10 contributes to JA‐amino acid biosynthesis and functions partially redundantly with AtJAR1 in sustaining flower development and the wound stress response in Arabidopsis.
TonoVet Plus®: Higher reliability and repeatability compared with Tono‐Pen XL™ and TonoVet® in rabbits
Authors: Barbosa Sirlene F. , Raposo Ana Claudia S. , Dórea Neto Francisco de Assis , Araujo Nayone L. L. C. , Oliveira Maria Madalena S. , Oriá Arianne P.
Published: March 2022

Objective

To evaluate the accuracy and repeatability of the Tono‐Pen XL™, TonoVet® and TonoVet Plus® tonometers by manometric evaluation, and to establish adjustment equations for intraocular pressure (IOP) estimates in rabbits.

Animal Studied

Rabbits.

Procedures

A postmortem study was conducted on seven rabbit eyes to verify the correlation between manometry and tonometry with an artificial incremental increase in IOP from 5 and 60 mmHg. A clinical study was conducted to evaluate accuracy and to establish reference values for the species, with measurement of IOP in 17 animals, for 2 consecutive days, with the same tonometers and calibrations used in the postmortem evaluations.

Results

There were strong linear trends for all evaluated tonometers. In the in‐vivo evaluation, the mean IOP values were: 14.23 ± 1.75 (Tono‐Pen XL™); 13.89 ± 2.07 (TonoVet® calibration mode ‘d’); 8.88 ± 1.24 (TonoVet calibration mode ‘p’); 18.59 ± 1.94 (Tonovet Plus®). There was a significant difference in the two evaluation times for the two TonoVet® calibration modes. The adjustment equations generated from the manometry for the evaluated tonometers were: Y = 0.2570X + 2.219 (Tono‐Pen XL™), Y = 0.2289X + 2.389 (TonoVet® ‘d’), Y = 0.4043X + 4.062 (TonoVet® ‘p’), Y = 0.1233X + 0.3644 (TonoVet Plus®) (X is device‐estimated IOP).

Conclusions

All evaluated tonometers were well correlated with the manometry, with an underestimation of IOP by all devices. Applying adjustment formulas may compensate for systematic errors. TonoVet Plus® was well tolerated, and showed better repeatability and reliability in successive evaluations.
Distribution and phylogenetics of hepatitis E virus genotype 4 in humans and animals
Authors: Li Bingzhe , Wagner Abram L. , Song Yujian , Chen Xiangxiang , Lu Yihan
Published: March 2022

Background

Worldwide, hepatitis E virus (HEV) infection is considered a significant public health concern. In particular, HEV genotype 4 (HEV‐4) has spread to more areas and host species. In this study, we describe the global distribution of HEV‐4 and characterize HEV‐4 subtypes by host, country and year of isolation.

Methods

We retrospectively collected HEV‐4 sequences available before December 31, 2019, in GenBank. HEV‐4 and its subtypes were determined using phylogenetic comparison with HEV reference sequences. Information on the isolation of the sequences was extracted from the GenBank or original publications. Temporal, spatial and host characteristics of the sequences were summarized and nucleotide similarity was calculated based on five amplified fragments within HEV genome, stratified by host, country and year.

Results

A total of 2295 HEV‐4 complete and partial nucleotide sequences were studied. The majority (92.7%) was isolated in China's mainland, Japan, Hong Kong and France. A total of 20 animal hosts were documented, though swine remained predominant (71.7%). Globally, prevalent HEV‐4 subtypes changed remarkably over the last 18 years. Subtypes 4a, 4b, 4d and 4h were most commonly isolated (80.3%). Subtypes 4c, 4e, 4f, 4g and 4i remained limited in temporal distribution. High nucleotide similarities were observed between the sequences amplified in HEV ORF2, in the same and neighbouring countries, and in similar animal hosts.

Conclusion

China and Japan are endemic for HEV‐4, and have all the subtypes. In Europe, France has a high prevalence of HEV‐4. Increases in affected areas and animal hosts imply consistent cross‐border and cross‐species transmission.
Reorientation of Free-Falling Legged Robots
Authors: Charlet Mark , Gosselin Clément
Published: March 2022

Based on the cat-righting reflex, this paper presents two reorientation maneuvers for legged robots that can produce roll and pitch reorientation during free fall. In order to better describe and plan these maneuvers, two separate, but equivalent, theoretical frameworks that describe the kinematic and dynamic behavior of free-floating articulated architectures are explored and developed. A nine-degree-of-freedom quadruped robot architecture is then presented and used to demonstrate the proposed maneuvers. Finally, kinematic and dynamic simulations of this architecture are performed. The results validate the presented theoretical framework and demonstrate that both roll and pitch reorientations are obtained through the application of the presented maneuvers.
Integrating ecological and molecular data to investigate species maintenance and interspecific hybridization between the redbreast sunfish (Lepomis auritus) and the pumpkinseed sunfish (Lepomis gibbosus)
Authors: Flamio Richard , Levano Samantha R. , Kashiwagi Tom , Makkay Amanda M. , Hekkala Evon R.
Published: March 2022

True sunfishes (genus Lepomis Rafinesque, 1819) of North America are renowned for hybridization, although hybrids often comprise only a fraction of the sunfish population in natural systems. Species boundaries may be maintained through premating mechanisms (e.g., ethological and habitat isolation), which may be facilitated by the promiscuous sunfish mating system; primarily, singular males guard nests that multiple females visit. Natural hybridization occurs between redbreast ( Lepomis auritus (Linnaeus, 1758)) and pumpkinseed ( Lepomis gibbosus (Linnaeus, 1758)) sunfishes, but there is no published research on its extent and causes. In this study, we assessed the relationship between ecological variables and the prevalence of hybridization in a sunfish population in a freshwater lake. Nests of both species were evaluated for differences in substrate, date, water depth, temperature, and dissolved oxygen. Sequencing of one fragment of nuclear DNA (calmodulin intron 4) and one fragment of mitochondrial DNA (12S) was employed on adult males and eight offspring from each nest to determine genetic identity and hybridization direction. Nonparametric tests found a significant difference in substrate between species’ nests ( p < 0.01), warranting further investigation into nest substrate as a mechanism for species maintenance. Furthermore, we observed asymmetrical hybridization with the less abundant species (redbreast sunfish) disproportionately affected.
MEASURING FINANCIAL MARKET RISK CONTAGION BETWEEN CHINESE AND OTHER ONE BELT ONE ROAD COUNTRIES’ STOCK MARKETS
Authors: XU HAIFENG , ZHANG JIAWEN , CHEN ZHEN
Published: March 2022

In this paper, we employ the dynamic Markov regime-switching copula model to measure the financial risk contagion among the One Belt One Road (OBOR) countries. To investigate the impact of the OBOR initiative, we divide the sample period into two subsamples and calculate the daily low/high tail dependence by adopting international stock market index data from January 2004 to March 2020. The results provide evidence of financial risk contagion effects, an asymmetric risk spillover and increased tail dependence between the Chinese stock market and those of other OBOR countries.
Message Transmission Strategy Based on Recurrent Neural Network and Attention Mechanism in Iot System
Authors: Gou Fangfang , Wu Jia
Published: March 2022

With the popularization of the Internet of Things technology and the improvement of 5G communication technology, the influence of mobile devices on the network structure is increasing. The devices in the network are usually regarded as social users that transmit information. Because the movement of users is dynamic and random, it is more difficult for complex networks to grasp the changing rules of their topological structure. The data transmission model established by considering only the historical behavior of users can no longer meet the demand for fast transmission of large-capacity data. Based on this, this paper proposes a dynamic personalized data transmission model (GRDPS) that considers the recurrent neural network and attention mechanism. First, it uses a recurrent neural network to build users’ personalized preferences and model the user’s historical behavior. Then, GRDPS introduces an attention mechanism to dynamically weight historical user behaviors based on the user’s current message transmission. It is different from the previous methods of modeling user historical behaviors. Based on the requirements of user dynamics, GRDPS effectively considers the temporal characteristics of user historical behaviors and automatically learns the evolution law of user behaviors. Based on the demand of user randomness, GRDPS fully considers the characteristic correlation between the user’s historical behavior and current transmission demand. Finally, GRDPS combines these two points to obtain a personalized ranking of users. The simulation results show that the delivery rate of GRDPS is up to 0.95. Moreover, its data transmission delay and network overhead are better than other methods in the experiment.
CHARACTERIZATION OF DEFECTS IN TUNGSTEN SAMPLES INTERESTED IN PFM STUDIES USING POSITRON ANNIHILATION AND PHOTOLUMINESCENCE SPECTROSCOPY
Authors: TORABI M. , KAKUEE O. , SOBHANIAN S. , KOUHI M.
Published: March 2022

The defect structure of four pure tungsten samples is investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD), photoluminescence (PL) and positron annihilation spectroscopy (PAS) techniques before and after annealing. The results of the SEM and XRD analyses show that the grain size is increased up to 43.3[Formula: see text][Formula: see text]m, and their growth in the (2 0 0) orientation occurs at 1673[Formula: see text]K. Also, the smooth of the peaks at 1673[Formula: see text]K in the PL test demonstrates the increase of the size of defects of the sample. Moreover, the results of the PAS indicate a decrease in the concentration of defects and an increase in their size at 1673[Formula: see text]K, which confirms the results obtained from the PL measurement. The collected results from the four examination techniques are in close agreement with each other and reveal that w ith the increase in the annealing temperature of tungsten samples, a gradual coalescence of the defects would happen to lead to an increase in their size and hence a reduction in their number as well as preferred grain growth in the (2 0 0) orientation and virtually perfect recrystallization of the samples at higher temperatures.
Dielectric relaxations in NASICON-type Li1.25Zr1.75Al0.25(PO4)3 solid electrolyte
Authors: Dwivedi Sushmita , Badole Manish , Gangwar Kaushal , Rajput Harsha , Kumar Sunil
Published: March 2022

In this work, the conduction and relaxation behavior of lithium-ion conducting monoclinic Li[Formula: see text]Zr[Formula: see text]Al[Formula: see text](PO[Formula: see text] (LZAP) ceramic prepared via sol–gel method was investigated. Rietveld refinement of the X-ray diffraction data confirmed the structure of LZAP as monoclinic with space group [Formula: see text]21/[Formula: see text] at room temperature. The permittivity data were fitted using a modified Cole–Cole equation containing the complex conductivity terms to rationalize the giant dielectric constant and loss factor observed at lower frequencies. In addition, fittings revealed the presence of two thermally activated dielectric relaxations processes in LZAP ceramics, which were attributed to the lithium ions movement within the grain and grain boundary confines. The activation energies computed from the Arrhenius fitting of relaxation times associated with the grain and grain boundary regions were [Formula: see text]0.447 ± 0.009 eV and [Formula: see text]0.46 ± 0.01 eV, respectively. The activation energies for grain and grain boundary Li[Formula: see text] conduction were also found to have similar values ([Formula: see text]0.42 eV for grain, and 0.46 eV for grain boundary).
Follow the Timeline! Generating an Abstractive and Extractive Timeline Summary in Chronological Order
Authors: Chen Xiuying , Li Mingzhe , Gao Shen , Chan Zhangming , Zhao Dongyan , Gao Xin , Zhang Xiangliang , Yan Rui
Published: March 2022

Today, timestamped web documents related to a general news query flood the Internet, and timeline summarization targets this concisely by summarizing the evolution trajectory of events along the timeline. Unlike traditional document summarization, timeline summarization needs to model the time series information of the input events and summarize important events in chronological order. To tackle this challenge, in this article we propose our Unified Timeline Summarizer, which can generate abstractive and extractive timeline summaries in time order. Concretely, in the encoder part, we propose a graph-based event encoder that relates multiple events according to their content dependency and learns a global representation of each event. In the decoder part, to ensure the chronological order of the abstractive summary, we propose to extract the feature of event-level attention in its generation process with sequential information retained and use it to simulate the evolutionary attention of the ground truth summary. The event-level attention can also be used to assist in extracting a summary, where the extracted summary also comes in time sequence. We augment the previous Chinese large-scale timeline summarization dataset and collect a new English timeline dataset. Extensive experiments conducted on these datasets and on the out-of-domain Timeline 17 dataset show that our Unified Timeline Summarizer achieves state-of-the-art performance in terms of both automatic and human evaluations.

1
The Comparative Effects of English and Persian Cultural Background Knowledge on EFL Learners’ Listening Skill
Authors: Widodo Mulyanto , Saenko Natalya Ryafikovna , Campos-Ugaz Osmer , Saavedra-López Miguel A. , Núñez Lira Luis Alberto , Razavi Seyedeh Sahar , Keezhatta Muhammed Salim , Fedorova Natalia , Hoi Huynh Tan , Ilyin Aleksander G.
Published: March 2022

This research compared the impacts of Persian and English cultural background knowledge on Iranian EFL learners’ listening skill. To that purpose, the Oxford Quick Placement Test (OQPT) was given to 86 Iranian EFL students; 50 of them were chosen as research participants. The respondents were then divided into two equal experimental groups (EGs) at random (Persian culture and English culture). A listening pretest was then given to both groups. The individuals in both EGs were then given the treatment. The researchers taught one EG by using the English cultural materials, while they taught the other group through the Persian cultural materials. The data were analyzed by utilizing paired samples and independent samples t-tests after the listening posttest was administered. The results showed that both EGs performed better on their posttests than on their pretests, and that there were no significant differences between the impacts of English cultural background knowledge and Persian cultural background knowledge on the listening skills of EFL students. The implications of this research can persuade EFL English teachers to incorporate more cultural-based materials into their teaching process.
Effects of High‐Energy Extracorporeal Shockwave Therapy on Pain, Functional Disability, Quality of Life, and Ultrasonographic Changes in Patients with Calcified Rotator Cuff Tendinopathy
Authors: Fatima Arooj , Ahmad Ashfaq , Gilani Syed Amir , Darain Haider , Kazmi Shiza , Hanif Kamran
Published: March 2022

Objective. The current trial was designed to evaluate the effects of high‐energy shockwave therapy on objective and subjective outcomes among participants with calcified rotator cuff tendinopathy. Methods. This parallel‐group, randomized trial consists of 42 patients affected by calcific tendinopathies divided into two groups of 21 participants. Patients having calcified tendinopathy aged between 30 and 65 years with type A or B calcification were selected in the trial after signing the written consent form. Participants in the ESWT+RPT group received eight sessions of shockwaves, while the RPT group was treated by routine physical therapy. About 2000 shockwaves of 0.32 mJ/mm2, 120 Hz per treatment, were given as 12 sessions for the first six weeks (2 sessions/week). Pain intensity and shoulder functional ability, ultrasonographic changes, and quality of life were assessed with the numeric pain rating scale (NPRS), Constant‐Murley score (CMS), ultrasonography, and Western Ontario rotator cuff index (WORC). Results. There were significant differences regarding NPRS and CMS between the two groups, at baseline and 6th and 12th weeks after intervention (p < 0.05). Within‐group differences also showed statistically significant results after treatment (all p < 0.05). Significant results were seen in the WORC and ultrasonographic results pre‐ and posttreatment; more significant findings were found in the experimental group as compared to others. Conclusion. High‐energy shockwave therapy has been proved to be effective and thus strongly recommended for the management of calcified rotator cuff tendinopathy, improving the pain, functionality, and quality of life of these participants and decreasing the size of calcified deposits. Shockwave therapy is proved to be superior to routine physiotherapy.
The Value of High-Resolution Ultrasound Combined with Shear-Wave Elastography under Artificial Intelligence Algorithm in Quantitative Evaluation of Skin Thickness in Localized Scleroderma
Authors: Jia Kun , Li Huiying , Wu Xiaojing , Xu Caina , Xue Hongyuan
Published: March 2022

The aim of this study was to explore the value of high-resolution ultrasound combined with shear-wave elastography (SWE) in measuring skin thickness in patients with localized scleroderma (LS). Fifty patients with LS diagnosed by pathology in the hospital were selected as the research object, with a total of 96 lesions. Healthy people (50 cases) in the same period were selected as the control group. The skin thickness of the abdomen, chest, and left finger of the two groups was compared. The traditional nonlocal means (NLM) algorithm was improved by changing the Euclidean distance and introducing a cosine function, which was applied to the ultrasonic imaging intelligent diagnosis of patients with localized scleroderma. SWE imaging was evaluated, and the results demonstrated that LS lesion edema stage accounted for 7.29%, hardening stage occupied 43.75%, and the proportion of atrophy stage reached 48.96%. When the size of shell was 1 mm, maximum elastic modulus (Emax) was 0.984, mean of elastic modulus (Emean) was 0.926, and electro-static discharge (Esd) was 0.965. When the size of shell was 2 mm, the elastic moduli around lesions were as follows: Emax was 0.998, Emean was 0.968, and Esd was 0.997. By comparing the skin thickness of the abdomen, chest, and left finger, it was found that there was a significant difference between the LS group and the control group (

P
<
0.05

). When the shell was 2 mm, the effect of sensitivity specificity on SWE imaging was better than that when the shell was 1 mm. In summary, the improved NLM algorithm showed excellent denoising effects on the ultrasonic images of LS patients. Besides, it could assist clinicians in ultrasonic imaging diagnosis for LS patients and effectively improve the diagnostic accuracy of diseases.
Promoting Regional Economic Transformation Forecast Based on Intelligent Computing Technology
Authors: Cai Hongbiao
Published: March 2022

The core of the value of artificial intelligence is to integrate with the real economy and become more dependent on local industries. In the entire artificial intelligence + industry development process, many new changes have appeared. This article mainly studies how to promote regional economy based on smart technology. In the context of rapid economic development, the significance of artificial intelligence and the necessity of regional economic transformation are put forward. The model has designed the national science and technology mechanism framework from the four directions of technology guidance, technology service, technology innovation, and technology balance; following the cultivating ideas from products to innovative industries to innovative intelligent environments, due to the low income elasticity of product demand, technological innovation is mainly based on the dissemination of emerging technologies outside the industry and the lack of coordination between companies under the fiercely competitive market structure; the focus is on promoting the continuous improvement of labor productivity. The experimental results prove that the emerging technology industries of enterprises can promote economic transformation in the era of artificial intelligence, provide a reference for better optimization of industrial innovation and development, and provide methodological support for the government to establish sound emerging technology business models and optimized management methods.
Design and Fabrication of Biodegradable Antenna Using Jute Material for UWB Application
Authors: Mary Joy Kinol. A. , Devaerakkam Marshiana , Godwin Immanuel D. , Raghavan Krishnamoorthy Narasu , Prince Grace Kanmani , negash Kassu
Published: March 2022

Ultra-Large Band (UWB) is a radio technology used for the transmission and distribution of radio energy over a wide frequency band with low power spectral density. A newer UWB Microstrip patch antenna is designed using a jute material as a substrate because of its durability and CO2 and water footprint. The ecological impact is relatively small with Cradle to Cradle, biodegradable with 100% compostable, and extremely strong. The jute substrate is reinforced to make it nonflexible and hydrophobic for further better electrical and mechanical properties, and it is treated with the conductive polymer sodium alginate; the results were compared with the raw hydrophilic jute substrate. The proposed antenna design and results were compared with the similar antenna using the FR4 substrate of a dielectric constant of 4.4 and a thickness of 1.6, and the ultra-wideband spectrum range from 3.1 to 10.6 GHz. It is used for both uplink and downlink transmission of local area network (LAN), wide area network (WAN), and satellite communications spectrum (SCP). The performance of this network provides a wider bandwidth transmission for the range of 1 to 14 GHz applications.
Associations of Clinical and Molecular Characteristics with the Response to Immune Checkpoint Blockade in Advanced Gastric Cancers
Authors: Xu Xiaoqing , Li Jingjing , Gao Yiding , Lv Wangxia , Wei Qing , Tang Xiaowan , Hu Jinlin , Yuan Xing , Wu Wei , Zhang Lingnan , Luo Cong , Chen Lei , Ying Jieer , Zhu Xiu , Xu Qi
Published: March 2022

Purpose. Immunotherapy provides a new treatment option for advanced gastric cancer (AGC). This study aims to explore the response markers of immunotherapy in AGCs. Methods. Next-generation sequencing was performed on 44 AGC patients who received immune checkpoint inhibitors and the associations between their outcomes after combination immunotherapy, and the clinicopathological/molecular characteristics were analyzed. Results. The current study cohort had a median progression-free survival (PFS) of 5.9 months, an overall survival (OS) of 12.1 months, and an objective response rate (ORR) of 36.4%. Through multivariable analysis of the clinical characteristics, primary tumor resection (HR = 2.66, 95% CI: 1.06–6.70,

p
=
0.037

) and increased proportion of lymphocytes after combination immunotherapy (HR = 0.40, 95% CI: 0.16–0.99,

p
=
0.048

) were revealed as independent predictors for patient outcomes. All the 18 patients who underwent genetic profiling were microsatellite-stable with a median TMB of four mutations per Mb. ATM alterations, PI3K pathway mutations, increased TMB, and positive PD-L1 expression were associated with the increased trend of PFS and ORR. According to the combination of baseline lymphocyte count, ATM mutation, TMB status, and PD-L1 expression, patients were stratified into higher- and lower-risk groups, with the lower-risk group showing improved PFS (HR = 4.7e−10, 95% CI: 0–inf,

p
=
0.02

) and ORR (75% vs. 0%,

p
=
0.007

). Conclusion. Several highly relevant potential biomarkers predictive of immunotherapy response in AGC patients have been identified in this research.
A Study of Logistic Regression for Fatigue Classification Based on Data of Tongue and Pulse
Authors: Shi Yu Lin , Jiang Tao , Hu Xiao Juan , Cui Ji , Cui Long Tao , Tu Li Ping , Yao Xing Hua , Huang Jing Bin , Xu Jia Tuo
Published: March 2022

Background and Objective. Fatigue is a subjective symptom which is hard to quantify, it is prevalent in the subhealth and disease population, and there is still no accurate and stable method to distinguish disease fatigue from subhealth fatigue. Tongue diagnosis and pulse diagnosis are the reflection of the overall state of the body, and the modern research of tongue diagnosis and pulse diagnosis has made great progress. This study aims to explore the distribution rules of tongue and pulse data in a disease fatigue and subhealth fatigue population and evaluate the contribution rate of tongue and pulse data to fatigue diagnosis through modeling. Methods. The Tongue and Face Diagnosis Analysis-1 instrument and Pulse Diagnosis Analysis-1 instrument were used to collect the tongue image and sphygmogram of the subhealth fatigue population (n = 252) and disease fatigue population (n = 1160), and we mainly analyzed the tongue and pulse characteristics and constructed the classification model by using the logistic regression method. Results. The results showed that subhealth fatigue people and disease fatigue people had different characteristics of tongue and pulse, and the logistic regression model based on tongue and pulse data had a good classification effect. The accuracies of models of healthy controls and subhealth fatigue, subhealth fatigue and disease fatigue, and healthy controls and disease fatigue were 68.29%, 81.18%, and 84.73%, and the AUC was 0.698, 0.882, and 0.924, respectively. Conclusion. This study provided a new noninvasive method for the fatigue diagnosis from the perspective of objective tongue and pulse data, and the modern tongue diagnosis and pulse diagnosis have good application prospects.
Study on the Fracture Evolution Law of Coal Based on Image Retrieval Method and X-Ray Computed Tomography
Authors: Wu Yan , Wang Dengke , Pang Xiaofei , Zhang Hang
Published: March 2022

The combination of real-time computed tomography (CT) scanning test and loading test can visualize the evolution process of defects such as internal pores and fissures in the coal. The axial deformation of the loaded coal sample will change the layers of the same section in the real-time CT scanning test, which will affect the analysis of fracture progression. To address the concern, we presented a CT image similarity retrieval method. The dynamic development law of fracture networks under triaxial stress was investigated using image processing technologies. The results reveal that the CT images of the coal sample in the same section can be obtained using the proposed CT image similarity retrieval method, which can more accurately characterize the fracture distribution and dynamic evolution law. The coal sample under triaxial stress experienced three fracture evolution stages: the closure in the compaction and elastic stages, the initiation and development in the plastic yield stage, and the rapid expansion and penetration in the postpeak stage. The variation trend of two-dimensional fracture ratio and fracture volume was consistent. The analysis is conducive to clarifying the coal failure mechanism under triaxial stress.
College English Teaching Quality Monitoring and Intelligent Analysis Based on Internet of Things Technology
Authors: Wang Xin
Published: March 2022

With the continuous development of network communication, modern control, information perception, artificial intelligence, and other technologies, the Internet of Things technology has also been more comprehensively developed and grown, and it is playing an increasingly important role in various fields of production and life. Due to the low efficiency and cumbersome procedures of the existing college English teaching quality assessment, this study intends to propose a new method to deal with this problem. Through this research, we get the following: (1) use static weight equalization method, dynamic weight adaptation method, and iterative weight method to filter and analyze the original data received by mobile phones and discard some obviously wrong values in the preprocessing. Analyzing the number requirements of the game model, the supply operation reference model, and the IoT technology upgrade model for the number of demand points, the results show that the IoT technology upgrade model requires the least number of demand points. (2) Optimize the related parameter information of the IoT system model, including candidate numbers, number of students in class, adjustment coefficient, Di, turnover rate, system cost, and total system consumption. The Internet of Things technology upgrade model performed best.

Adjustment
 
coefficient
=
−
102

;

Di
=
−
99.6

;

turnover
=
−
100

;

system
 
cost
=
−
123.2

;

SL
=
−
123.5

;

SP
=
−
99.8

. (3) Passed the test of the number of questions and feedback rate, classroom number, classroom test scores, new vocabulary number, system scoring, and comprehensive scoring to judge the model. It is found that the number of questions, feedback rate, class number, and class test scores, number of new vocabularies, system scores, and comprehensive scores of the upgraded and transformed models of the Internet of Things are above the standard values, indicating that the model is highly efficient and intelligent.
Determinants of Antenatal Care Service Satisfaction among Women in Ethiopia: A Systematic Review and Meta-Analysis
Authors: Seyoum Kenbon
Published: March 2022

Background. Antenatal care service satisfaction is a measure of the degree to which a woman seeking care is happy with the antenatal care service provided to her. Thus, this systematic review and meta-analysis aims to identify factors that determine antenatal care service satisfaction among women in Ethiopia. Methods. PubMed, Hinari, and Google Scholar were systematically searched for eligible studies. In addition, national university digital libraries were also searched. The Joanna Briggs Institute’s (JBI) critical appraisal tools were used to assess the quality of the included articles. The Cochrane Q-statistics and I2 tests were used to assess heterogeneity among the included studies. Publication bias was assessed using Egger’s test. Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross-Sectional Studies. The extracted data were analyzed using STATA version 14 software and the results were presented using the forest plot. Results. Of the 274 articles identified through the systematic search of the literature, 13 studies fulfilling the inclusion criteria were included in this meta-analysis. First antenatal care visit (AOR: 0.62 and 95% CI: 0.40, 0.96), women waited <60 min (AOR: 1.87 and 95% CI: 1.40–2.50), women whose privacy was maintained (AOR: 3.91 and 95% CI: 1.97–7.77), women treated respectfully (AOR: 5.07 and 95% CI: 2.34–10.96), and unplanned pregnancies (AOR = 0.28 and 95% CI: 0.10–0.77) were significantly associated with antenatal care service satisfaction. Conclusion. The study assessed the determinants of antenatal care service satisfaction in Ethiopia. First antenatal care visit, waiting time (<60 min) to see the care provider, maintenance of privacy, respectful treatment, and pregnancy unplanned were found to be determinants of antenatal care service satisfaction. Counseling a woman to comply with a minimum required antenatal care visits and compassionate and respectful maternity care will increase maternal satisfaction with the antenatal care services.
A tradução intercultural como sensibilização para aspectos culturais no ensino de alemão
Authors: Lima Adriana Borgerth Vial Corrêa , Stanke Roberta Cristina Sol Fernandes
Published: March 2022

Língua e cultura vistas como duas faces de uma mesma moeda já é um ponto pacífico na área da Didática (Kramsch 1996; Koreik 2013). Apesar disso, ainda hoje há muitos questionamentos sobre como abordar essa temática em sala de aula (Kramsch 2013). Nesse contexto, o presente artigo tem como objetivo analisar o processo de construção da sensibilização intercultural por meio da tradução intercultural a partir da análise de cartas pessoais escritas por uma brasileira a seus familiares no Brasil durante sua estada na Alemanha, na qual relata suas vivências e experiências com os festejos de carnaval. A análise das cartas baseia-se nos conceitos de relato de viagem e escritor viajante (Bassnett 2004, 2007), ambos oriundos da perspectiva descritivista da Tradução, bem como no conceito de tradutor intercultural (Lima 2021); e a análise do processo da construção da sensibilização intercultural fundamenta-se no Fluxo de Sensibilização Intercultural (Lima 2021). Assim, através desses relatos em cartas pessoais, torna-se possível observar a construção da sensibilização intercultural da escritora viajante no papel de tradutora intercultural e, a partir do entendimento desse processo, torna-se possível tomar consciência de alguns aspectos relevantes para o ensino de língua alemã.
Literatura e confiança: apontamentos sobre parâmetros de análise
Authors: Mathias Dionei
Published: March 2022

Confiança tem um lugar de destaque na consolidação do si, na apropriação de mundo e nas interações humanas. Quando textos literários representam interações entre sujeito e mundo, a confiança fundamenta motivações, ações e as transformações do sentido que emergem dessa interação. Nesse horizonte, este artigo deseja discutir o conceito de confiança em três esferas: individual, sociocultural e existencial. Para ilustrar a argumentação, o artigo recorre a três obras de Goethe: Torquato Tasso, Egmont e Ifigênia em Táurida. A introdução adumbra o lugar da confiança no discurso da Modernidade; nas seções que seguem busca-se refletir sobre cada uma das esferas e o modo como ela são representadas no texto literário. O artigo conclui que a confiança como parâmetro de análise transcende os discursos literários nacionais, funcionando como instrumento para identificar novas camadas de sentido.
Sprachmittlung – Mediation: Welche Konsequenzen für die Praxis aus dem Companion Volume? Eine curriculumanalytische Untersuchung und theoretisch-konzeptionelle Modellierungen für den Fremdsprachenunterricht
Authors: Reimann Daniel
Published: March 2022

Der Beitrag hat zum Ziel, in die Modellierung der Mediation im Companion Volume (Europarat 2018) zum Gemeinsamen europäischen Referenzrahmen für Sprachen/GeR (Europarat 2001) einzuführen und ihr Potential für die Praxis des Fremdsprachenunterrichts zu untersuchen. In seinem curriculumanalytischen Teil setzt sich der Aufsatz mit der Konzeption von Mediation im GeR und seiner Überarbeitung im Companion Volume auseinander. Er untersucht diese – mit Fokus auf die Neuerungen des Companion Volume – vor der Folie des Konstrukts der Sprachmittlung, das in den letzten beiden Jahrzehnten in der deutschen Bildungspolitik und Fremdsprachendidaktik entwickelt wurde. Im Anschluss daran untersucht der Beitrag, welche Anregungen für die Weiterentwicklung der Mediation im Fremdsprachenunterricht aus dem Companion Volume hervorgehen und identifiziert dafür drei Kategorien. Schließlich werden prototypische Beispiele für den Fremdsprachenunterricht und zwei konkrete Praxisbeispiele für Deutsch als Fremdsprache in Brasilien vor allem für die erste Kategorie, „Aktivitäten, die gängige Praxis im Fremdsprachenunterricht waren oder sind, aber nunmehr unter den Vorzeichen der „Mediation“ neu reflektiert werden könnten“, gegeben.
Mediação ‒ Tradução & Interpretação ‒ e consciência linguística: do ‘velho’ resiliente no ‘novo’
Authors: Oliveira Paulo
Published: March 2022

Propõe-se aqui que os processos de ‘mediação’ no ensino-aprendizagem de línguas adicionais deveriam incorporar uma componente de reflexão, assumindo uma concepção de linguagem de extração não essencialista. Nota-se que no debate em curso são mobilizadas concepções anacrônicas do que seja ‘traduzir’, o que dificulta uma compreensão adequada do processo e sua (re-) incorporação nas práticas didáticas. O argumento recorre a elementos retirados de longa experiência prática, aliada a significativa produção teórica nas áreas em jogo.
Governança de turismo de base comunitária e estudo dos entraves para a consolidação de duas comunidades em Recife (Pernambuco, Brasil) sob a luz do Modelo de Análise da Governança
Authors: Graciano Pollyanna Fraga , Holanda Luciana Araújo de
Published: March 2022

A partir da proposta de uma nova visão paradigmática do fenômeno turístico, o turismo de base comunitária (TBC) incrementa a atividade turística inspirada no desenvolvimento sustentável e no protagonismo dos atores locais, contribuindo para a geração alternativa de renda e melhoria da qualidade de vida das comunidades. Embora sejam constantemente estudadas e debatidas pela academia, as iniciativas de TBC enfrentam dificuldades para consolidar-se no mercado turístico e tendem a fenecer. Pesquisas realizadas na área apontam que a governança é um dos obstáculos para esta consolidação. No Recife, duas comunidades, a Bomba do Hemetério e a Ilha de Deus, desenvolvem iniciativas de TBC, porém ambas não se firmaram como destino turístico regular. Logo, este estudo analisa a governança dessas iniciativas recifenses por meio da aplicação do Modelo de Análise da Governança (MAG) do TBC, adotando como construtos a participação, a transparência e a eficácia. A pesquisa caracteriza-se como qualitativa, descritiva e explicativa. A coleta de dados ocorreu por meio de observação, pesquisa documental e entrevistas semiestruturadas. Para o tratamento dos dados coletados, empregou-se a análise de conteúdo do tipo categorial, obedecendo ao critério lexical. Entre os entraves para a consolidação das iniciativas recifenses destacam-se os conflitos internos, baixo relacionamento com o poder público e a alta dependência externa, inclusive de redes.
A rotina dos produtores de tv na pandemia: a atuação das fontes na coprodução de conteúdo jornalístico
Authors: Siqueira Fabiana , Nascimento Gilmara Dias do
Published: March 2022

A pandemia da Covid-19 mudou, em diversos aspectos, a vida da humanidade. No campo do jornalismo, foi preciso adequar algumas práticas para preservar a saúde de jornalistas e entrevistados, levando a um aumento na solicitação de vídeos realizados pelo público. Este artigo analisa a consolidação das fontes como produtoras de conteúdo na TV Correio, afiliada da Record TV na Paraíba, e como isso impactou as rotinas produtivas dos produtores dos telejornais no contexto da pandemia. O estudo foi realizado a partir da observação participante feita entre março e setembro de 2020 na emissora e, também, por meio da realização de entrevistas semiestruturadas com os produtores. Entre outras questões, constatou-se que houve uma mudança no papel do produtor, que passou também a orientar as fontes na produção de material audiovisual, criando mecanismos para isso. Essa nova função do produtor deve perdurar nas rotinas produtivas mesmo após o fim da pandemia.