bluuebunny/crossref_metadata_2025 huggingface dataset:
Parental Knowledge, Self-confidence, and Usability Evaluation of a Web-Based Infographic for Pediatric Concussion: Multimethod Study
Authors: Campbell Alyson , Hartling Lisa , Plourde Vickie , Scott Shannon D
Published: April 2022

Background

Concussions, which are known as mild traumatic brain injuries, are complex injuries caused by direct or indirect blows to the head and are increasingly being recognized as a significant public health concern for children and their families. Previous research has identified few studies examining the efficacy of educational interventions on parental concussion knowledge. The aim of this research was to actively work together with children who have experienced a concussion and their parents to develop, refine, and evaluate the usability of a web-based infographic for pediatric concussion.

Objective

The objective of this study was to report on the usability of the infographic, parental knowledge, and self-confidence in pediatric concussion knowledge before and after exposure to the infographic.

Methods

A multiphase, multimethod research design using patient engagement techniques was used to develop a web-based infographic. For this phase of the research (usability, knowledge, and confidence evaluation), parents who could communicate in English were recruited via social media platforms and invited to complete web-based questionnaires. Electronic preintervention and postintervention questionnaires were administered to parents to assess changes to concussion knowledge and confidence after viewing the infographic. A usability questionnaire with 11 items was also completed.

Results

A web-based, infographic was developed. The infographic is intended for parents and children and incorporates information that parents and children identified as both wants and needs about concussion alongside the best available research evidence on pediatric concussion. A total of 31 surveys were completed by parents. The mean scores for each item on the usability surveys ranged from 8.03 (SD 1.70) to 9.26 (SD 1.09) on a 10-point Likert scale, indicating that the usability components of the infographic were largely positive. There was no statistically significant difference between preintervention and postintervention knowledge scores (Z=−0.593; P=.55; both preintervention and postintervention knowledge scores had a median of 9 out of 10). In contrast, there was a statistically significant difference between preintervention (mean 3.9/5, SD 0.56) and postintervention (mean 4.4/5, SD 0.44) confidence in knowledge scores (t30=−5.083; P<.001).

Conclusions

Our results demonstrate that parents positively rated a web-based, infographic for pediatric concussion. In addition, although there was no statistically significant difference overall in parents’ knowledge scores before and after viewing the infographic, their confidence in their knowledge did significantly increase. These results suggest that using a web-based infographic as a knowledge translation intervention may be useful in increasing parents’ confidence in managing their child’s concussion.
Self-Directed Learning Mahasiswa Keperawatan pada Implementasi E-Learning di Pembelajaran Praktik Profesi Ners
Authors: Suryani Kharisma Eka , Gautama Made Satya Nugraha , Sunaryo Eri Yanuar Budi Akhmad , Harjanto Totok
Published: April 2022

Background: E-learning method could develop student’s self-directed learning abilities, as its advantage. Self-directed learning (SDL) becomes essential in education since it encourages student to learning, skill development, and professional practice. Educators need to combine current learning process with information technology and e-learning to promote student readiness for SDL abilities.Objective: To describe self-directed learning readiness (SDLR) for nursing students during e-learning implementation in clinical rotation nurse professional program.Method: This was a descriptive-quantitative study with a cross-sectional design conducted at PSIK FK-KMK UGM. Total sampling was applied and included 102 respondents. They were nurse professional program students who were taking basic nursing practice and nursing management courses from August to December 2018. Self-Directed Learning Readiness Scale (SDLRS) was used as data collection instrument which consisted of 40 items. Data was analysed using univariate approach.Result: There were 60,8% of Nurse Professional Program students who took e-learning courses had high SDLR scores (Mean=152,75; SD=13,362; Min=121; Max=195). The average SDLR scores in each subscale were reaching 3,61 on self-management, 3,98 on the desire to learn, and 3,86 on self-control.Conclusion: The SDLR level of nurse professional program students who took basic nursing practice and nursing management courses showed high results in the implementation of e-learning. ABSTRAKLatar belakang: E-learning memiliki keunggulan dalam mengembangkan kemampuan belajar mandiri siswa (self-directed learning). Self-directed learning (SDL) penting dalam pendidikan karena memotivasi mahasiswa untuk belajar, mengembangkan keahlian, serta melatih profesionalitas. Pendidik perlu menggabungkan proses pembelajaran dengan teknologi informasi dan e-learning guna memfasilitasi kesiapan mahasiswa terhadap kemampuan SDL (self-directed learning readiness).Tujuan: Untuk mengetahui gambaran SDLR mahasiswa profesi ners.Metode: Penelitian ini merupakan penelitian descriptive-quantitative dengan rancangan cross sectional yang dilakukan di PSIK FK-KMK UGM. Pengambilan responden secara total sampling, responden sebanyak 102 mahasiswa profesi ners stase praktik keperawatan dasar dan manajemen keperawatan pada periode Agustus-Desember 2018. Instrumen yang digunakan adalah Self-Directed Learning Readiness Scale (SDLRS) yang terdiri atas 40 pertanyaan. Data penelitian dianalisis menggunakan analisis univariat.Hasil: Sebanyak 60,8% mahasiswa profesi ners pada pembelajaran e-learning ini memiliki nilai SDLR yang cenderung tinggi (Mean=152,75; SD=13,362; Min=121; Max=195). Rata-rata skala SDLR pada tiap sub-skala adalah 3,61 pada manajemen diri, 3,98 pada keinginan untuk belajar, dan 3,86 untuk kontrol diri.Simpulan: Tingkat SDL mahasiswa profesi ners menunjukkan kecenderungan tinggi pada pembelajaran e-learning.
A BRIEF NOTE ON PALLEY’S CRITICISM OF NEW DEVELOPMENTALISM
Authors: Oreiro José Luis , De Paula Luiz Fernando
Published: April 2022

This short paper offers some critical remarks on Palley’s critical assessment of New Developmentalism. It argues that Palley’s criticism is based on a narrow view of the Brazilian New Developmentalist school and largely ignores the work of other members of this school and even other writings by Bresser-Pereira. This “original sin” in Palley’s assessment leads him to associate New-Developmentalism unfairly with Neo-Liberalism, as well as setting up a false opposition between Classical Developmentalism and New Developmentalism, rather than seeing both as strands of developmental theory designed for different historical phases of Latin American development.

 

UNA BREVE NOTA SOBRE LA CRÍTICA DE PALLEY AL NUEVO DESARROLLO

RESUMEN

Este breve artículo ofrece algunas observaciones críticas sobre la valoración que hace Palley del nuevo desarrollismo. Sostiene que la crítica de Palley se basa en una visión estrecha de la escuela brasileña del nuevo desarrollismo e ignora en gran medida el trabajo de otros miembros de esta escuela e incluso otros escritos de Bresser-Pereira. Este “pecado original” en la evaluación de Palley le lleva a asociar injustamente el nuevo desarrollismo con el neoliberalismo, así como a establecer una falsa oposición entre el desarrollismo clásico y el nuevo desarrollismo, en lugar de ver ambos como vertientes de la teoría del desarrollo diseñadas para diferentes fases históricas del desarrollo latinoamericano.
MORE ON THE LIMITS OF NEW DEVELOPMENTALISM
Authors: Palley Thomas I.
Published: April 2022

Oreiro and de Paula’s (2022) reply to my article (Palley, 2021) further convinces me that New Developmentalism (ND) substantially misconstrues the development challenge and ND’s policy recommendations lean in a Neoliberal direction. The critique of ND is not its emphasis of the importance of manufacturing. It is the regressive inclination, the narrowness of policy recommendations, neglect of the transformation dimension of development, and neglect of the implications of the shift to a post-industrial era.

 

MÁS SOBRE LOS LÍMITES DEL NUEVO DESARROLLISMO

RESUMEN
La crítica de Oreiro y de Paula (2022) a mi artículo (Palley, 2021) me convence aún más de que el nuevo desarrollismo (ND), sustancialmente, comprende mal el desafío del desarrollo y que sus recomendaciones de política se inclinan en una dirección neoliberal. Mi crítica al ND no es a su énfasis en la importancia de la manufactura, sino a la inclinación regresiva y a la estrechez de sus recomendaciones de política, a su omisión tanto de la dimensión de la transformación del desarrollo como de las implicaciones del cambio hacia una era postindustrial.
Mujeres liberales y presbiterianas en el contexto del Congreso Liberal de 1901
Authors: Mendoza García Leticia
Published: April 2022

El texto analiza la actuación de las mujeres liberales y presbiterianas de Zitácuaro, Michoacán, en el contexto del Congreso Liberal de San Luis Potosí. La presencia de las mujeres en los espacios públicos, como los clubes femeniles, los periódicos y las tribunas cívicas, fue un logro mayúsculo en una sociedad que había destinado estos espacios a los varones. El objetivo de esas mujeres fue contrarrestar la influencia del clero sobre el elemento femenino, por medio de la creación de un proyecto de escuela liberal capaz de formar mujeres modernas, con la suficiente preparación para involucrarse en los espacios cívicos, políticos y democráticos en igualdad de condiciones con los varones.
Digital Media and Women: Usage, Challenges and Outcome (A Study of Women in Jaipur)
Authors: Batra Nikita
Published: April 2022

Abstract: The advent of Internet has taken the world in a swirl. Living in a digital age, we treat Internet as our lifesaver and rely on this technology for a broad array of things from paying our bills to finding a life partner, so on and so forth. Technology has made things easier but it has also created many threats for the society and it is constantly increasing. It is a need to be careful all the time while accessing Internet otherwise a person can easily become the victim. Each one of us our connected through technology that let people communicate with each other. The availability of mobiles, personal computers, laptops and ease of access to Internet made things easier but at the same time the risk of being the victim of crime in virtual world has also increased. The more usage also affecting the health of people and women have been seen more affected to it. Cybercriminals keep their eye on various digital media platforms including job and marriage website where women post their personal information. The revealing of such information has made women more a target of cyber crime. It has also been seen that women are less aware about the laws regarding cyber crime and most of the times they shy or have fear of reporting such type of crimes. Keywords: Digital, Digital Media, Social Media, Crime, Cyber Crime, Morphing, Cyberspace, Netizens, Cyber Bullying, Hacking.
Desafíos para la docencia universitaria. Una propuesta desde el enfoque
histórico-cultural
Authors: Rubio González Juan
Published: April 2022

Este libro comprende que todo proceso educativo debe considerar y orientarse a partir de relaciones sociales educativas determinadas histórico-culturalmente. Por esto se propone comprender la docencia universitaria como una actividad social, contextualizada y relacional, que utiliza las contradicciones/tensiones inherentes a estos ámbitos como fuerzas impulsoras de la enseñanza-aprendizaje.
PENGALAMAN PEMBENTUKAN KONSEP DIRI PENGGEMAR DALAM MENGIKUTI KEGIATAN "IDOL YOU CAN MEET" DI THEATER JKT48 JAKARTA
Authors: Mulya Siti Ntara Muthmainah , Tomohardjo Irmulan Sati
Published: April 2022

The formation of the concept of self is also owned by JKT48 fans. The formation of the concept of the self is influenced by the experience carried out by fans in doing "Idol You Can Meet" at Theater JKT48 Jakarta, interaction between fans and member, interact with fellow JKT48 fans, join to a community that is associated with JKT48. The method used in this research is qualitative - phenomenology. Primary data collection in this reseach is in-depth interview techniques, observation and documentation. The results of the research are explained the experiences endured by fans, The formation of the concept of self in fans after following the activities of "Idol You Can Meet" JKT48, the interaction between fans, and the experiences about socializing among fans in a community.Conclusion of this research is fans can form the self-concept about their self being fans without opening up their I dentity as fans by directly in their environment that are not closest, fans can get many experiences about memorable experiences and disappointing experiences after during following the activities of "Idol You Can Meet" JKT48, the positive influence of member to fans for doing good activities, and fans can socialize with other fans, make a new friend with another fans and join or make community for socialize and support JKT48 together.
TEKNIK PENGGUNAAN MEDIA SOSIAL “FACEBOOK DAN INSTAGRAM” DALAM MEMBANGUN BRAND AWARENESS PT. WISATA ANUGERAH ABADI
Authors: Fadhilah Ahmad
Published: April 2022

Companies in the current era use social media as a medium for the formation of Brand Awareness, specifically social media Facebook and Instagram. Wina Tour is an effort that is engaged in the field of Tour & Travel services that use social media Facebook and Instagram to make Brand Awareness as Agnet Travel. The purpose of this research is to study the results of using Facebook and Instagram social media in the formation of Wina Tour Brand Awareness.This research refers to the theory about the technique put forward by Uchjana Effendy The technique is essentially planning and management to achieve a goal. But achieving that goal, the technique does not function as a road map that only shows direction, but must be able to show how the operational point is.The method used in this research is qualitative descriptive through in-depth interviews with Vienna Tour social media managers and Vienna Tour customers using Facebook and Instagram.The results of this study indicate that the utilization of Facebook and Instagram by Wina Tour in the formation of the desired image has been successful, where through published content, Vienna Tour customers Facebook and Instagram users have the perception that on Vienna Tour they get information about traveling. But there are still things that need to be maximized by Wina Tour to be able to achieve the goal of forming its image to the fullest.
REPRESENTASI CITRA PRINCESS DALAM IKLAN “DREAM BIG, PRINCESS” (Analisis Semiotika Charles Sanders Peirce )
Authors: Richi Juliano
Published: April 2022

A Princess is a title possessed by a female figure in a leadership court of a nation with a Monarch system in its government, however these days, the figure of a Princess tend to be portrayed incorrectly in various media resulting a construction of fallacy in the society’s point of view towards it. As an effort to deconstructs the fallacy built in the society referring to the Princess figure by employing its successful franchise of the Disney Princess, Disney attempts to instill an early educational message regarding the value of feminism and gender equality towards children globally by utilizing a campaign known as ‘Dream Big, Princess’ referring to the cause and delivering the message through commercials which one of them was specifically published as the ‘Where Will Your Imagination Take You?’ version. Done by applicating the constructivism paradigm, this research was intented to find the commercial way of utilizing various sign to representate an ideal image of the Princess’ figure as a role model. By adopting the qualitative methods and the viewpoint of Charles Sanders Peirce’s Semiotic theory, this research was done to the main analysis unit consisting of 11 different sequences from the commercial itself. By the end of the research, signs implying inclusivity, exploration, determination, creation, potential, braveness and feminism shows and as a whole, resulting how a Princess tend to be constructed more of an inspirative figure in the eyes of children which their presence as a role model is able to motivate children with various backgrounds to realize their full potential in their way of reaching their own hopes and dreams.
PENGARUH PEMROSESAN INFORMASI SECARA SENTRAL DAN PERIFERAL “PESAN SOCIAL MEDIA” TERHADAP KEPUTUSAN MEMILIH JASA JNE DI JAKARTA BARAT
Authors: Ramadhani Nadhilah , Tri Atmodjo Juwono
Published: April 2022

The development of technology today, Social Media has become a tool used by companies to help prospective customers process information that suits their needs. Companies that utilize social media as marketing tools are PT. Tiki Line Nugraha Ekakurir, better known as JNE. JNE uses Instagram to provide information. This study is to determine the extent of the influence of Central Information Processing "Social Media Message" Against the Decision to Choose JNE Services in West Jakarta with the Elaboration Likelihood Model theory. This study uses a quantitative approach to the type of explanatory research. With the survey method by distributing questionnaires to 196 respondents obtained from calculations using the purposive sampling technique. The data analysis technique used is a Likert scale with data analysis of multiple linear regression equations. The results of this study are customers who have research criteria only 161 respondents. There is an influence between Central Information Processing of 39.2% and Peripherals of 65.5%. And there is a joint influence on the Decision to Choose JNE Services by 68.4%. Based on the research results, the researcher gave a suggestion that the JNE social media team could focus the content delivered in the form of information packaged more simply and easily understood, although central information such as information related to tariffs, types of services including promo or discount programs still needed to be informed.
PERAN PRODUSER DALAM PROSES PRODUKSI WEB SERIES PERDANA WAHANA HONDA
Authors: Nazilah Silmi
Published: April 2022

Wahana Honda is one of the businesses engaged in the distribution of Honda motorcycles and the service of Honda motorcycles is one of the services of Wahana Honda. This research uses descriptive research method with a qualitative approach. The method used is a case study by conducting in-depth interviews with informants. The results of this study indicate that the role of producers in the Wahana Honda Prime web series process consists of 3 stages, in pre-production which of course it is related in making themes, story ideas, cinematographic processes in the production and editing of images. In the production process the producer is fully responsible for controlling, supervising, and coordinating to all the crew involved for the smooth running of their production, carrying out production in accordance with the script and shooting script made by the producer. In post production there are 2 editing processes, namely offline and online. The producer ensures and supervises the production work in accordance with the client's direction and deliver the results in accordance with the agreed time.
POLA KOMUNIKASI KOMUNITAS JARINGAN PENGUSAHA NASIONAL BANDUNG DALAM MEMPERTAHANKAN EKSISTENSINYA
Authors: FAUZIAH NAJMATUL
Published: April 2022

Communities are generally formed because there are similarities, visions and missions shared by the people who join in it. Bandung City National Entrepreneur Network. Association of Entrepreneurs whose goal is to establish Japnas, to help the growth of the Indonesian economy, by defending our own products. Japnas Bandung was also established in 2018. This research is how the communication pattern of the Bandung National Entrepreneur Network community in maintaining its existence. This study uses a qualitative approach with a descriptive method. Data collection techniques using interviews, observation and documentation. In this study, the communication pattern used is one-way communication, namely the Japnas website, two-way WhatsApp group media, and multi-way communication occurs during face-to-face meetings such as annual events, Branch Deliberations, Annual Meetings, Break Fasting Together, Halal Bi Halal and Meetings. weekly/monthly. Communication activity in Japnas Bandung City uses descriptive communication, Prescriptive communication (Giving Instructions).
AKTIVITAS MARKETING PUBLIC RELATIONS DALAM MEMBANGUN BRAND POSITIONING DI PT FOODS BEVERAGES INDONESIA
Authors: Witoko Vrendi
Published: April 2022

The method used in this study is descriptive qualitative, primary data collection methods with in-depth interview techniques, and documentation, while secondary data collection is done by collecting data through research and library studies and then the validity of the data is tested through triangulation techniques. The results of the research from Marketing Public Relations Activities in Building a Brand Position at PT Foods Beverages Indonesia in the eyes of consumers, through the Drink Promotion at Chatime Setia Budi One Jakarta, which succeeded in making consumers keep buying and even making favorite drinks and maintaining good relations between PT. Foods Beverages Indonesia with its customers, so as to create goodwill and mutual understanding from the public in building customer trust and interest in participating in the Promotion Program organized by PT. Foods Beverages Indonesia. Conclusion of this research Every activity carried out in the company in this case Marketing Public Relations activities have a positive and negative impact in terms of promotions that are held positive impacts that must be able to be maintained in order to make Brand Chatime more advanced and always develop innovations while the negative impacts regarding the program that is carried out because of an existing obstacle must be able to immediately overcome it well in order to achieve a customer or buyer satisfaction to be able to always enjoy the chatime by having fun and comfort.
STRATEGI PUBLIC RELATIONS STASIUN TELEVISI DALAM MEMBANGUN CORPORATE IMAGE (Studi Kasus Program Community Relations NET. Good People di Stasiun Televisi NET.)
Authors: Muthia Eggi Listy Bahatis
Published: April 2022

NET television station. is a station that has a young age compared to other televisions in Indonesia, but is much loved by loyal viewers. Seeing the many loyal viewers of the television station, public relations creates a place to gather and exchange the views of loyal viewers of the NET television station. as the NET community. Good people. The purpose of this study was to find out the strategies carried out by the public relations television station NET. in building an image in the community.In this study using the public relations strategy theory Scoot M. Cutlip & Allen H. Center This study uses a constructivist paradigm with a qualitative approach to case study methods. Data collection techniques with interview techniques and observations and supported by literature studies. The results of this study are public relations television station NET. apply the Scoot M. Cutlip & Allen H.Center theory in implementing the public relations strategy. Besides that, "NET. TV is COOL "is a corporate image that is valued by the community. While the obstacles faced are when looking for targets to become members of the NET community. Good people.
Predictors of post-acute COVID-19 pneumonia recovery status
Authors: Nafakhi Ahmed , Rabeea Ihsan S , nafakhi hussein , Al-Darraji Rasha
Published: April 2022

Background: Clinical trajectory and potential predictors for post-acute
covid-19 are largely unknown. Methods: One hundred fifty one patients
with COVID-19 infection and features suggestive of pneumonia were
enrolled in the analysis. Results: Mild lung injury and high platelet
mean volume(PMV) were predictors for complete recovery. Low Hb at
presentation, length of ICU stay, extensive lung injury, old age and
shortness of breath at presentation were predictors for persistent
shortness of breath, while high Hb, extensive lung injury, and
productive cough at presentation were predictors for persistent fatigue.
Conclusion: mild lung injury and high PMV were predictors for complete
recovery.
Vertically transmitted Epichloë systemic endophyte enhances drought tolerance of Achnatherum inebrians host plants through promoting photosynthesis and biomass accumulation
Authors: Zhong Rui , Zhang Xingxu , Li Chunjie , Nan Zhibiao
Published: April 2022

Achnatherum inebrians (drunken horse grass, DHG) plants, a dominant
grass species in the arid and semi-arid regions of northwest China,
symbiotic with an Epichloë fungal endophyte, is well adapted to drought.
However, little is known about how the presence of the foliar Epichloë
endophyte enhances the tolerance of DHG to drought at the molecular
level. This study explored the positive effects of the presence of the
Epichloë endophyte on plant growth, biomass, and photosynthetic
efficiency and processes of DHG under non-drought and two drought
(moderate and severe) treatments, using RNA sequencing to compare
transcriptomes. The transcriptome results showed that 32 selected
unigenes involved in the photosynthesis processes within Epichloë
symbiotic plants were differently expressed (DEGs) versus non-symbiotic
plants. The majority of these selected DEGs were up-regulated in
Epichloë symbiotic plants versus non-symbiotic plants, such as
up-regulated unigenes (c51525.graph_c1, c47798.graph_c0 &
c64087.graph_c0) under drought conditions. In line with the
transcriptomes data, the presence of the Epichloë endophyte promoted the
photosynthetic rate and biomass accumulation of DHG plants, and the
relationship between photosynthetic rate and biomass is liner and
significant. The presence of the endophyte only increased the biomass
per tiller of DHG plants under drought. This study has provided further
insights into the molecular mechanisms underlying enhanced plant growth
and drought tolerance of DHG host plants of the Epichloë endophyte.
Incidental carotid sinus hypersensitivity in a patient presenting with syncope: A case report
Authors: Dhakal Bishal , Pathak Bishnu , Simkhada Nabin , K.C Prabhat , Subedi Binaya , Thapa Dilip
Published: April 2022

Carotid sinus hypersensitivity is one of the unexplained causes of
syncope in old age. A 56-year-old male, known case of coronary artery
disease (CAD) and diabetes mellitus (DM), presenting with syncope, was
diagnosed as carotid sinus hypersensitivity incidentally. Hence, the
rare disorder like carotid sinus hypersensitivity should also be
considered.
A case of unresectable combined hepatocellular and cholangiocarcinoma treated with atezolizumab plus bevacizumab
Authors: Saito Naoto , Hatanaka Takeshi , Nakano Sachi , Hazama Yoichi , Yoshida Sachiko , Hachisu Yoko , Tanaka Yoshiki , Yoshinaga Teruo , Kashiwabara Kenji , Norio Kubo , Hosouchi Yasuo , Tojima Hiroki , Kakizaki Satoru , Uraoka Toshio
Published: April 2022

An 81-year-old man initially underwent right hepatic lobectomy for liver
cancer and was pathologically diagnosed with combined hepatocellular and
cholangiocarcinoma (CHC). At 13 months after resection, multiple lymph
node metastases were observed. We started atezolizumab plus bevacizumab
(Atez/Bev), achieving a 7.5-month progression-free survival. Atez/Bev
might exhibit efficacy for CHC patients.
High-performance swing-enhanced floating inverter amplifier using correlated level shifting technique
Authors: Zhao Yibo , Zhang Shan , Liu Junqi , Zhao Menglian , Tan Zhichao
Published: April 2022

An improved swing-enhanced floating-inverter amplifier (SEFIA) using the
correlated-level-shifting (CLS) technique is presented, simultaneously
achieving both high gain and high output swing. The proposed SEFIA uses
a reused capacitor to replace the dynamic biasing capacitor and input
coupling capacitor. One of the two reservoir capacitors, which supplies
power to the amplifier in the auto-zero phase, is also reused in the
level shifting phase. Post-layout simulation results show that in the
180 nm CMOS process; the DC gain remains above 73dB for clock
frequencies between 50 kHz to 400 kHz. Compared to conventional FIA with
CLS, the proposed SEFIA with a 1.8V supply achieves the 1.54 times
output swing increase at a clock frequency of 250 kHz. The CLS technique
boosts the DC gain of the proposed SEFIA from 50dB to 74.6dB.
Bent Coplanar Waveguide Feeds for Balanced Planar Antennas and Arrays
Authors: Lv Xianyang , Zhang Yongwei , Fu Yanwei , Shi Quan , El-Makadema Ahmed
Published: April 2022

Planar antenna arrays of a balanced structure are of great importance in
many applications due to their features including low-profile, wideband
and high polarisation purity. However, feeding such antennas adds great
complexity in terms of manufacturing and reduces the performance due to
production of common mode propagation. A method for feeding such
antennas using coplanar waveguide on a thin substrate is proposed. Not
only does it terminate the antenna of a balanced structure with a
single-ended feed but it also enables impedance transformation. The
design was an attempt towards a completely printed front-end that
incorporates the antenna elements and their feeding circuits on bendable
substrates. The electromagnetic performance has been validated with a
dual polarized prototype and its prospect for ultrawideband arrays e.g.,
5G sub-6 GHz or square kilometre array, was explored.
Variation in body size drives spatial and temporal variation in lobster-urchin interaction strength
Authors: DiFiore Bartholomew , Stier Adrian
Published: April 2022

Size-scaling relationships generated across huge variation in body mass
from zooplankton to elephants offer critical insight into understanding
similarities in species interactions across ecosystems. Yet to what
extent ecologists can borrow from these relationships to effectively
predict interactions between a single species pair remains poorly
understood. Here, we combine experiments and long-term data to test how
accurately published size-scaling relationships predict interactions
between an economically and ecologically important predator-prey pair.
We demonstrate that interaction strength is highly dependent on predator
size, prey size, and prey density. We then used this relationship to
predict plausible interaction strengths across ten years of data at five
sites. Our analysis reveals that variation in body size accounts for up
to 91% of the variation in interaction strength compared to density.
However, predictions generated from even the closest size-scaling
relationship from the literature underestimated the strength of
interactions by a factor of 4.
Phyloepidemiology and adaptive evolution of SARS-CoV2 during the first and second wave of COVID-19 in India
Authors: Tewari Anuj , Kumar Rajesh
Published: April 2022

This study was conducted to know the various circulating lineages of
SARS-CoV-2, prevalent mutations in lineages, and selective pressure
analysis on the genome of SARS-CoV-2 during the first and second wave of
the COVID-19 pandemic in India. For this purpose total of 1451 sequences
from June 2020-June 2021 spanning from various regions of India were
downloaded from NCBI and GISAID. The sequences were blasted using the
Pangolin COVID-19 lineage assigner. Total, forty-one lineages were found
to be circulating in India during this one year. Thirty-five lineages
were circulating during the first wave and twenty lineages were
circulating during the second wave out of which six were new lineages.
During the first wave, in 2020 only one Variant Of Concern (Alpha) was
found and during the second wave in 2021 three variants of concern
(Alpha, Beta, and Delta) were in circulation. One Variant Under
Monitoring was also prevalent during the second wave. The most frequent
mutations observed were S: D614G, NSP3: F106F, NSP 12b: P314L, ORF3a:
Q57H, M: Y71Y, NSP14:C279C, S: D294D, N: S194L. Interestingly, the ten
most mutated samples belonged to Delta variant of B.1.617.2 lineage and
all were found in the second wave which justifies the severity of the
second wave. Five mutations L452R, T478K, E484Q, N501Y, and D614G in the
spike protein responsible for increased transmissibility and reduction
in neutralization by convalescent sera were majorly prevalent during
second wave out of which D614G, L452R, and T478K were present at
prevalence rate of 88.25%, 21.04%, and 16.80%, respectively. The
major selection was purifying selection, however, few sites in the NSP2,
NSP3, NSP13, S protein, ORF3a, and ORF9 evolved under positive
selection. We hereby also report six novel mutations, three in NSP2
(P129A, V381A, V381F), one in NSP3 (P822S), and one in S protein (Q23R)
evolving under positive selection pressure.
Nociones de la investigación y el potencial de la investigación aplicada como estrategia de innovación
Authors: GUTIERREZ NOVOA YEIDER
Published: April 2022

En el contexto educativo actual el componente investigativo es tema de gran interés para las diferentes entidades de formación, siendo el encargado de direccionar y administrar las ideas que surgen desde la mirada crítica del individuo. Este logra convertirlas en realidades a través de proyectos de investigación que generan diversos planes de acción para atender las situaciones problémicas identificadas; para ello se pretende proporcionar las nociones de la investigación y las bases conceptuales necesarias para contextualizar la investigación aplicada como una estrategia de innovación capaz de generar nuevos conocimientos. Es necesario esta revisión a través de la metodología para la evaluación de artículos y estudios empíricos que abordan las nociones de la investigación básica y aplicada, en la cual se confirma que el rol de la educación superior es determinante para avanzar en el ámbito de la investigación y favorecer al desarrollo del país
The Toxic versus Therapeutic Interactions of Tyrosine Kinase Inhibitors and Radiation Therapy
Authors: Sokol Gerald
Published: April 2022

Introduction: Progress in both the development of Tyrosine Kinase Inhibitors (TKIs) and modern radiation therapy (RT) have opened new horizons for the safe and effective treatments of cancer. Combination therapies of TKIs and radiation therapy have been evaluated with variable sequencing and dosing of both agents. Radiation therapy induces cellular damage to cancer and normal tissue DNA by the production of direct and indirect ionization leading to a cascade of biological events. These ultimately lead to potential loss of cellular reproductive capacity, cell death or impotency. Repair mechanisms of RT-induced cell damage require repair pathways dependent on TK. TKIs are key regulators of cellular function and signaling proteins that catalyze phosphorylation reactions of tyrosine molecules. The purpose of this study was to briefly review the basic biology of RT and TKIs and to review the modern literature pertaining to the toxic and therapeutic effects of their combination in the treatment of cancer based on preclinical and clinical data. Methods: A retrospective review of the basic biology of RT and TKIs with the aim of identifying their combined toxicity and benefit in the treatment of cancer wa performed. A systematic search of the standard published radiotherapeutic, radiobiology, chemotherapy and radiotherapy texts, PubMed, Google Scholar, and Clinical Key using the search terms; TKI, RT and combination TKI and RT from 1985-2020 was employed. Data were abstracted from 220 entries from the literature published in English. Issues of toxicity and therapeutic efficacy were defined to evaluate the safe and effective use of combined modality therapy (CMT). Results: Few randomized studies were available for high-level recommendations. The combined treatment of cancer with TKIs and RT may have benefit for palliation, progression free survival, and potential survival under well-defined circumstances. Any benefit of combined therapy is accompanied by significant potential for enhanced radiation toxicity in addition to the baseline potential toxicities of both agents. Conclusion: The data reviewed suggest potential benefit from the CMT of TKIs and RT but at a significant risk of toxicity, which may include severe, hematological, cardiac, gastrointestinal, pulmonary and central nervous system toxicity. Further randomized prospective studies are necessary to define their safe and effective combined therapies.
Sled Dogs as a Model for Brown Fat Research
Authors: Dunlap Kriya
Published: April 2022

Brown adipose tissue (BAT) has the unique function of burning energy to create heat through the process of non-shivering thermogenesis. Activation of BAT in humans as a means of combating obesity is an active area of research, yet reliability of methods for recognizing and monitoring activation needs further research. This study assessed the feasibility of thermal imaging for monitoring BAT activation in an animal model, Alaskan sled dogs, which have been used extensively in coldweather metabolism and nutrition research. BAT activation was monitored monthly over four months in a cohort of five sled dog puppies. A change in temperature accompanies BAT activation. Therefore thermal images of the chest area were taken pre- and post-cold exposure. Concentrations of two plasma biomarkers associated with non-shivering thermogenesis, irisin and fibroblast growth factor 21 (FGF21) were also analyzed. No significant temperature change or concentration changes in irisin or FGF21 were observed between pre-and post-cold exposures. To our knowledge this is the first study in dogs, therefore the results provide methodology strategies for future study design. Given the potential benefits of BAT activation in humans, the validation of thermal imaging as a non-invasive monitoring technique and the use of an animal model could better inform the treatment of metabolic diseases.
Applications of Cone Beam Computed Tomography in Orthodontics: An Overview
Authors: Agrawal Poonam
Published: April 2022

Cone beam computerized tomography (CBCT) has changed numerous aspects of dentistry and added great value to its diagnostic phase also as that of orthodontics. Three-dimensional imaging CBCT has the potential to improve the diagnosis and treatment planning of cases. The introduction of cone beam computerized tomography (CBCT) technology to dentistry and orthodontics revolutionized the diagnosis, treatment and monitoring of orthodontic patients. The information obtained from CBCT imaging provides several substantial advantages. For example, CBCT imaging provides accurate measurements, improves localization of impacted teeth, provides visualization of airway abnormalities, it identifies and quantifies asymmetry, it are often wont to assess periodontal structures, to spot endodontic problems, to plan placement sites for temporary skeletal anchorage devices, and to look at condylar positions and mandibular joint (TMJ). Moreover, CBCT imaging involves only a minimal increase in radiation dose relative to combined diagnostic modern digital panoramic and cephalometric imaging. Cone-beam computed tomography (CBCT) is now being widely used in orthodontic practice. On the one hand, there is an increasing need of CBCT for diagnosis and research, and on the other hand, there is a broad concern for the exposure to radiation. Prescribing CBCT scan requires judicious clinical judgment to maximize the benefits and minimize the harm. The best way to reduce unnecessary ionizing radiation from CBCT is to follow recommended guidelines and ethical principles. CBCT provides a superb tool for accurate diagnosis, more predictable treatment planning, more efficient patient management and education, improved treatment outcome and patient satisfaction. This review discusses the utilization of CBCT in diagnosis and treatment planning in orthodontics.
Effects of Heavy Toxic Metals on Human Health and Methods of Determining their Content in Tea Sheets and Vegetables Grown in the Lankaran-Astara Region of the Republic of Azerbaijan
Authors: Mikayil Akbar Marrahamov
Published: April 2022

This paper examines the impact of heavy toxic metals on human health. It has been shown that the long-term accumulation of heavy metals in the body can lead to a slowdown in the development of physical, muscle and neurological degenerative processes that mimic certain diseases, such as Parkinson’s disease and Alzheimer’s disease. The transfer of heavy metals from ecosystem to human is also analyzed. It is noted that some heavy metals generate free radicals, which can lead to oxidative stress and cause other cellular damage, a carcinogenic effect, affecting a number of proteins. As a result of the measurement of mass concentrations of zinc, cadmium, lead and copper by inversion voltammetry after preliminary preparation of samples by wet mineralization, it was found that the content of concentrations of Zn, Cd, Pb, Cu in tea flashes was 3.50 ± 1.40 mg/kg, 0.03 ± 0.038 mg/kg, 0.370 ± 0.130 mg/kg, 3.20 ± 1.10 mg/kg, respectively Low Zn and Cd 0.56 ± 0.22 mg/kg and 0,0012 ± 0,0048 mg/kg, respectively, were found in fresh tomatoes, and Pb and Cu 0,013 ± 0,0045 mg/kg and 0.57 ± 0.21 mg/kg, were found in fresh cucumbers respectively. The content of mass concentrations of toxic metals Cd, Pb in all analysed samples of tea leaves and vegetables (tomatoes and cucumbers) is less than their permissible levels specified in regulatory documents in force in the Republic of Azerbaijan.
Evaluation of Changes in the Uptake of Heavy Metals in Leachate using Vetiver Phytoremediation
Authors: Rahnavard Aptin
Published: April 2022

The aim of this study was to evaluate the potential of uptake of heavy metals from waste leachate to determine the amount of uptake of lead, cadmium, manganese and nickel by vetiver was performed in greenhouse conditions. This research it was performed Based on a completely random design in three replications with four treatments Includes leachate, 0, 30, 60 and 100%. Data analysis was performed with Spss 19 software, comparison of mean treatments with analysis of variance and Duncan test at 1 % probability level and plotting of graphs with Excel software. The results showed that the uptake of heavy metals by the plant, There is a significant difference at the 99% level. Also by increasing leachate treatment levels, Root and shoot length, There is a significant difference at the 99% level. And with increasing levels of leachate treatment, the uptake of heavy metals has increased. The highest root uptake was with an average of 200.21 mg/kg. And in the shoot, was 147.93 mg/ kg in a total of four treatments. The highest rate of heavy metal uptake was related to 100% treatment with a total of 225.25 mg/kg in roots and 178.87 mg/kg in shoots for four metals lead, cadmium, manganese and nickel. Among the heavy metals absorbed in the roots and shoots, the highest levels were related to manganese, nickel, lead and cadmium, respectively. And manganese with an average of 123.88 mg, lead 91.08, nickel 79.69 and cadmium 53.49.27 mg/kg had the highest uptake by the plant. Also the biological concentration factor was more than one and the translocation factor was less than one The results showed that vetiver can be used as a Phytoestablization plant to purify contaminants. Vetiver can be considered as a refining plant due to its vegetative characteristics and cost-effectiveness.
Innate immunity and metabolism in the bovine ovarian follicle
Authors:   , Horlock Anthony D.
Published: April 2022

Postpartum uterine disease in dairy cows is associated with reduced fertility. One of the first and most prevalent bacteria associated with uterine disease is Escherichia coli. The bacterial endotoxin, lipopolysaccharide (LPS), accumulates in the ovarian follicular fluid of animals with uterine disease. The granulosa cells of the ovarian follicle respond to LPS by secreting pro-inflammatory cytokines, such as interleukin (IL)-1a, IL-1b and IL-8, and oocyte health is perturbed. Dairy cows also experience metabolic energy stress in the postpartum period, which is associated with an increased risk of developing uterine disease and ovarian dysfunction. This thesis explored the crosstalk between innate immunity and metabolic energy stress in bovine granulosa cells and cumulus-oocyte complex. Firstly, we found that glycolysis, AMP-activated protein kinase and the mechanistic target of rapamycin, regulate the innate immune responses to LPS in granulosa cells isolated from bovine ovarian follicles. Activation of AMP-activated protein kinase decreased the LPS-induced secretion of IL-1a, IL-1b, and IL8, and was associated with shortened duration of ERK1/2 and JNK phosphorylation. Next, we found that decreasing the availability of cholesterol or inhibiting cholesterol biosynthesis using short-interfering RNA impaired the LPS-induced secretion of IL-1a and IL-1b by granulosa cells. Furthermore, metabolic energy stress or inhibiting cholesterol biosynthesis in the bovine cumulus-oocyte complex modulated the innate immune responses to LPS, and perturbed meiotic progression during in vitro maturation. Finally, we explored an in vivo model of uterine disease in heifers, using RNAseq to investigate alterations to the transcriptome of the reproductive tract. We found that uterine disease altered the transcriptome of the endometrium, oviduct, granulosa cells and oocyte, several months after bacterial infusion; these changes were most evident in the granulosa cells and oocyte of the ovarian follicle. The findings from this thesis imply that there is crosstalk between innate immunity and metabolism in the bovine ovarian follicle.
Augmenting English public speaking skill through peer evaluation: a case study in Toastmaster International Club
Authors: Rifah Lailatul , Sabilah Fardini
Published: April 2022

Having peers to give public speaking feedback is always feasible to measure the learners’ performance. However, learners are unwilling to share their feedback in the evaluation due to hesitance. This research investigates the kind of peer evaluation elements that the Toastmaster evaluator used to evaluate the speakers and how the they interpret the evaluation given by their peers. An in-depth interview was used to analyze about the elements of peer evaluation and the speakers’ feedback towards peer evaluation. Snowballing technique was chosen to select the research subjects. Three research subjects, as the members of Toastmaster International (TMI) in Malang and Surabaya, Indonesia claimed that the elements of evaluation used in TMI increased the ability of public speaking. The assessment aspects were divided into three factors: the script, seen, and spoken. Meanwhile, other crucial evaluation elements in public speaking include the grammatical aspect and proper words instead of filler words. This research found that the TMI speakers felt very satisfied with the implementation of peer evaluation due to its effect on increasing confidence during performing public speaking. It can be implied that peer evaluation element can effectively be used to measure oral communication skills from peer’s point of view in TMI.