bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Minat Belajar Siswa dalam Penggunaan Aplikasi Belajar Quizizz pada Pembelajaran Tematik Kelas III Sekolah Dasar
Authors: Yulistiarawati Dewi Nur , Umayaroh Siti , Linguistika Yulia
Published: September 2021

Abstract: The purpose of this study was to describe the learning interest of class III B students at SDN Bumiayu 3 Malang City when learning without using the Quizizz learning application and to describe the learning interests of class III B students at SDN Bumiayu 3 Malang City when learning using the Quizizz learning application. The approach used is a mix method (combination research) with the type of research using descriptive research and the design method used is the parallel combined method design. Data were collected using a questionnaire (questionnaire), interviews and documentation. The results of the study showed that students' interest in learning without using the Quizizz learning application was categorized as moderate with a percentage of 63 percent. Then for students' interest in learning using the Quizizz learning application, the percentage of 83 percent is in the high category. There is an increase in interest in learning, namely 20 percent, so it can be concluded that the Quizizz learning application can be an alternative for teachers in using learning media during online learning during a pandemic to increase students' interest in learning, as well as create a more interesting, fun, not monotonous learning atmosphere for learning. followed by students, and utilize technology.

Abstrak: Tujuan penelitian ini adalah mendeskripsikan minat belajar peserta didik kelas III B SDN Bumiayu 3 Kota Malang ketika pembelajaran tanpa menggunakan aplikasi belajar Quizizz dan mendeskripsikan minat belajar peserta didik kelas III B SDN Bumiayu 3 Kota Malang ketika pembelajaran menggunakan aplikasi belajar Quizizz. Pendekatan yang digunakan yaitu mix method (penelitian kombinasi) dengan jenis penelitian menggunakan penelitian deskriptif dan desain metode yang digunakan yaitu desain metode gabungan paralel. Data dikumpulkan menggunakan kuesioner (angket), wawancara, dan dokumentasi. Hasil dari penelitian menunjukkan bahwa minat belajar peserta didik tanpa menggunakan aplikasi belajar Quizizz dikategorikan sedang dengan persentase 63 persen. Kemudian untuk minat belajar peserta didik menggunakan aplikasi belajar Quizizz menunjukkan persentase 83 persen yang termasuk kategori tinggi. Terdapat peningkatan minat belajar yaitu 20 persen, sehingga dapat disimpulkan bahwa aplikasi belajar Quizizz dapat menjadi alternatif guru dalam menggunakan media pembelajaran selama pembelajaran dalam jaringan di masa pandemi guna meningkatkan minat belajar peserta didik, serta menciptakan suasana pembelajaran yang lebih menarik, menyenangkan, tidak monoton untuk diikuti peserta didik, dan memanfaatkan teknologi.
ANALISIS PENGARUH TIPE INTERNAL SHADING SEBAGAI STRATEGI PENDINGINAN PASIF PADA BANGUNAN
Authors: Dewi Cynthia Permata
Published: September 2021

Abstrak: Strategi pendinginan pasif pada bangunan menjadi salah satu alternatif dalam memperoleh kenyamanan termal dengan meminimalkan konsumsi energi pendinginan bangunan. Posisi Indonesia yang dilewati oleh garis khatulistiwa mengakibatkan terjadinya penyinaran matahari sepanjang tahun. Hal ini memerlukan sebuah perlakuan khusus terhadap bukaan pada fasad bangunan. Penelitian ini bertujuan untuk menganalisis dan melihat pengaruh tipe internal shading pada interior bangunan terhadap variabel solar gain bangunan. penggunaan tipe shading berupa venetian blind, roller shades dan drapes akan diaplikasikan pada bangunan. hasil dari penelitian ini didapatkan bahwa penggunaan roller shades mampu menurunkan level solar gain sebesar 55 persen. Sedangkan penggunaan venetian blinds dan drapes memberikan hasil penurunan sebesar 31 persen dan 25 persen. Dari penelitian ini dapat disimpulkan bahwa penggunaan roller shades memberikan hasil yang cukup efektif dalam menurunkan solar gain pada bangunan.Kata-kata kunci: pendinginan pasif, internal shading, solar gainAbstract: Passive cooling strategy in buildings is an alternative in obtaining thermal comfort by minimizing building cooling energy consumption. The position of Indonesia, which is crossed by the equator, results in solar radiation throughout the year. This requires a special treatment of openings in the facade of the building. This study aims to analyze and see the effect of the type of internal shading on the interior of the building on the variable solar gain of the building. the use of shading types in the form of venetian blinds, roller shades and drapes will be applied to the building. the results of this study found that the use of roller shades was able to reduce the level of solar gain by 55 percent. Meanwhile, the use of venetian blinds and drapes resulted in a decrease of 31 percent and 25 percent, respectively. From this research, it can be concluded that the use of roller shades gives quite effective results in reducing solar gain in buildings.Keywords: passive cooling, internal shading, solar gain
Comparison of thermal response times of historical and modern building wall materials
Authors: YÜKSEL Ahmet , ARICI Müslüm , KARABAY Hasan
Published: September 2021

The study aims to identify the main reason of the thermal response time difference between historical and modern buildings. Therefore, in this study, the thermal response time of historical and modern wall structures and its effect on the interior air temperature change was investigated parametrically. Considering the environmental conditions of Kocaeli province, Turkey, the thermal response time of a historical building wall made of a cut stone was compared with those of brick and gas concrete wall structures having the same overall heat transfer coefficient using the second-order lumped capacitance approach. The insulation thicknesses of the three different construction materials for U-values of 0.6, 0.4 and 0.2 W/m2K were calculated and temperature variations of indoor environment, wall and insulation material were analyzed. In addition, the required thicknesses of insulation material to obtain the same heat transfer coefficients were determined in case of using the 0.1 m thickness of cut stone, brick and gas concrete structure materials. The maximum and minimum amplitudes of the inside air temperature were recorded as 0.59 and 0.18oC for the aerated concrete in Case 3 and for the
cut stone in Case 2, respectively. As a result, the walls with high thermal inertia are less affected by the changes in the environmental temperature although their U-value is relatively high. For this reason, it can be stated that one of the reasons why historical buildings have thick walls is to increase thermal inertia and thereby improve thermal comfort by reducing energy loss.
Analysis and simulation of thermal performance of a PTC with secondary reflector
Authors: REGUE Hanane Maria , BOUALI Belkacem , BENCHATTI Toufik , BENCHATTI Ahmed
Published: September 2021

In this paper, a numerical simulation of fluid flow and conjugate heat transfer in a solar thermal parabolic trough collector (PTC) system is presented. The simulation is being carried out on a prototype designed in the Mechanical Laboratory in order to analyze the performance of this system. The main objective is to compare the system performance with and without a secondary reflector (SR). PVSYST software is used to provide numerical temporal values of the solar heat flux in Laghouat city (ALGERIA). Solar flux density values for four days in different seasons have been taken. SolTrace code is used to determine the heat flux distribution on the absorber tube. The conjugate heat transfer and fluid flow equations in the tube absorber are solved by using ANSYS-CFX CFD software. A comparison between two cases (traditional PTC and PTC with parabolic secondary reflector) with the same working fluid (Therminol VP-1) is carried out. The obtained results show that the system performance are practically the same for the four seasons. Moreover, the performance of the system with a second collector is better than that without a second reflector with a ratio of about 1.65.
Numerical investigation of supercritical heat transfer of water flowing in vertical and horizontal tube with emphasis of gravity effect
Authors: SUNDRAVEL Anand , SURESH Sivan , DEENADAYALAN Santhoshkumar
Published: September 2021

Over a decade, coal-based thermal power plants are upgraded to operate at supercritical pressure conditions due to its high efficiency and low emissions. Water wall panels of a typical supercritical boiler are structured spirally in the lower furnace and vertically placed in the upper furnace. The spiral tubes are inclined at 19 to 22 degrees in which fluid behaves as in horizontal tubes. The design of water wall panels plays the key role in designing a supercritical boiler. The present work aims to numerically investigate the heat transfer behavior of both vertical and horizontal tubes at the supercritical conditions. Since the temperature distribution across the cross-section of vertical tube is uniform, a 2D axis symmetry tube has been considered for analyzing the vertical tube. Unlike vertical tube, the heat transfer characteristics is different for horizontal tubes. Therefore, a 3D tube has been modelled for the computation of horizontal tubes. In order to gain confidence, the present simulations are validated with experiments results available in the literature. Ansys-Fluent has been used in the present simulation. SST k-ω turbulence model is used in this analysis. In the present work, 10 mm diameter of 4m length of vertical tube has been chosen and simulated at low heat flux to mass flux ratio 0.27 and high heat flux to mass flux ratio 0.67 with pressure 241 bar. The effect of heat flux (q) to mass flux (G) ratio which is responsible for heat transfer enhancement and heat transfer deterioration has been studied for both vertical and horizontal tubes. The wall temperature has been plotted along the length of the tube for both top and bottom portion of horizontal tube and compared with wall temperature of vertical tube. The effect of buoyancy plays a vital role in the heat transfer behavior of horizontal
tube compared to vertical tube. Heat transfer deterioration occurs due to buoyancy which has a direct linkage with gravity. Three cases were studied, one with full gravity (factor 1), half gravity (factor 0.5) and zero gravity (factor 0). It has been observed that, sudden rise in wall temperature occurs for the case gravity factor 1.0, i.e, considering the gravity effect. For the case of zero gravity, no sudden peak of local wall temperature is observed due to the absence of buoyancy term in the Navier-Stokes equations. Some of the thermo-physical properties like velocity, turbulent kinetic energy, density, wall temperature and turbulent viscosity are analyzed for three cases.
Prevalence of metabolic syndrome and associated factors among human immunodeficiency virus patients on highly active antiretroviral therapy in North central Nigeria
Authors: Reng Rifkatu S. , Onwuegbuzie Gerald A. , Salisu Muaz , Anumah Felicia
Published: September 2021

Background: Metabolic syndrome (MS) is a complex disorder defined by cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus. The Use of Highly active antiretroviral therapy in HIV patients is associated with metabolic syndrome which increases the risk of cardiovascular disease (CVD). The aim of the study was to determine the prevalence of MS among HAART treated HIV patients and HAART naïve patients.Methods: This was a cross-sectional study that evaluated 581 (396 females, 184 males) consenting HIV patents in the hospital. Clinical characteristics, anthropometry, blood pressure, lipid profile, fasting blood glucose, fasting plasma insulin, CD4 cell counts and viral load were determined using appropriate standard techniques. MS was defined using International Diabetes Federation (IDF) cut-off values.Results: The overall prevalence of MS was 10.7%, with more females 52 (13.1%) than males 10 (5.4%), p=0.005. MS in patients on HAART was 58 (15.1%) and HAART naive 4 (2.0%). Overall, waist circumference, BMI, systolic blood pressure (BP), diastolic blood pressure (BP), triglycerides and fasting blood glucose were 82.7±11.5, 22.7±, 120.6±17.6, 77.5±10.6, 1.1±0.7 and 5.1±1.9 respectively. Patients with MS had significantly higher (p<0.05) waist circumference (94.1 vs 81.3 cm), BMI (24.8 vs 22.5 kg/m2), systolic BP (135.4 vs 118.8 mmHg), diastolic BP (86.2 vs 76.5 mmHg), triglycerides (1.3 vs 1.0 mmol/l) and fasting blood glucose (6.3 vs 4.9 mmol/l).  Insulin resistance (IR) was higher in patients with MS 11.8(7.9) compared with patients without MS 5.5 (6.8) p=0.02.Conclusions: Prevalence of metabolic syndrome in this study was lower than that reported in previous works, the prevalence is much higher in the HAART treated patients. The risk of MS were high triglycerides, hypertension and abnormal fasting blood glucose. There was significant association with the traditional risk factors, age, female gender and HIV duration.
Correlation of serum IgG antibodies to helicobacter pylori in chronic skin disorders: A case-control study
Authors: Gupta Kalpana , Jain Arushi , Yadav Tania , Gupta Pankaj , Kaur Navneet
Published: September 2021

It is known that chronic idiopathic urticaria occasionally develops in association with Helicobacter pylori infection, but this relationship remains unproven. Also, many studies show.

We investigated the role of H. pylori infection in patients of chronic idiopathic urticaria, other chronic skin disorders as well as healthy controls using urease breath test and immunoturbidimetry for anti H. pylori IgG antibodies. Three groups of eighty-nine patients each were taken as cases, controls and placebo controls respectively. All patients having IgG titer of 10U/ml or above and Urease Breath Test Positivity were considered positive.

: The positive rate of anti H. Pylori IgG antibodies was 78.65% (70/89) in case group, 84.71% (22/89) in controls with other skin disorders and 32.58% (29/89) in placebo control group. While positive rate for Urease Breath Test were found to be 79.8% (71/89) in cases, 35.95% (32/89) in controls with other skin diseases and 32.58% (29/89) in placebo controls.

In chronic idiopathic urticaria a high titer of anti H. pylori IgG and Urease Breath Test positivity suggests that inclusion of anti H. pylori therapy in it’s the management would be beneficial and would lead to lower rates of recurrence. Also, low positivity rates of Urease Breath Test and Anti H. pylori IgG in controls with other chronic skin diseases and placebo controls points towards no clear evidence to prove a causal relationship between these diseases and H. pylori infection.
A clinical study of dermatotses in neonates in Silchar medical college
Authors: Das Kinnor , Gupta Bhaskar , Das Sumit
Published: September 2021

According to WHO a neonate, is a child under 28 days of age. The neonatal skin changes show a wide geographic and ethnic variation. It is important to know the pattern of dermatoses prevalent among Indian children during the neonatal period.

The current study was conducted to study the prevalence of neonatal dermatoses in southern Assam and to study relationship of neonatal dermatoses with maturity and birth weight of neonates.

150 neonates who developed cutaneous lesions over a period of one year were examined. Proportion of each dermatoses and prevalence ratio were calculated using relevant formulae.

Out of the 150 neonates, 66 % neonates had transient physiological changes, 11.33% had congenital disorders and genodermatoses, 4.67% had iatrogenic complications, 30% had acquired skin diseases, 8% had neonatal infections and 2% had other miscellaneous diseases. The five most common dermatoses overall were diaper dermatitis (17.33%), miliaria (14%), erythema toxicum neonatorum (13.33%), infantile seborrheic dermatitis (12.67%), sebaceous gland hyperplasia (6%) and Mongolian spot (6%). Low birth weight babies had predilection for vernix caseosa, sucking blisters, candidiasis, miniature puberty, caput succedaneum, cephalohematoma, physiological jaundice, infantile acropustulosis, salmon patch, Epstein’s pearls/ Bohn's nodules, miliaria, sebaceous gland hyperplasia, neonatal acne, Mongolian spot, bullous impetigo, erythroderma Preterm neonates had predilection for vernix caseosa, sucking blisters, miniature puberty, candidiasis, Mongolian spot, caput succedaneum, cephalohematoma, erythroderma, miliaria, Epstein’s pearls/ Bohn's nodules and a positive association was seen between post-term neonates and physiological desquamation, diaper dermatitis. Neonatal psoriasis and neonatal dermatophyte infection were the unusual findings which we found in our study.
Efficacy of oral tranexamic acid versus triple combination for the treatment of melasma: A prospective, double blinded randomised controlled trial
Authors: Appannavar Shruti , Rohith  , Pise Gajanan
Published: September 2021

Melasma is a common acquired hypermelanosis characterized by irregular light to dark brown macules and patches seen mainly in women and over sun-exposed skin on the face. We have undertaken this RCT to compare the efficacy between oral Tranexamic acid and Topical Triple combination as Tranexamic acid is having good safety profile.

To compare the therapeutic efficacy of oral Tranexamic acid versus Topical Triple combination for the treatment of Melasma using MASI score. To compare the adverse effects profile of each treatment modality.

Total subjects (66 patients) were divided into 2 groups (A and B, each with 33 patients) by simple randomization method.Patients and analysers were blinded to treatments. Group-A received topical triple combination cream once daily (15-minutes) at night for 8 weeks followed by maintenance regimen of biweekly application of product for 4 weeks and oral placebo tablets (calcium gluconate 250mg) twice daily for 12 weeks. Group-B received oral Tranexamic acid tablets 250mg twice daily for 12 weeks with topical placebo cream (Moisturizer) once daily at night for 8 weeks followed by maintenance regimen of biweekly application of product for 4 weeks. MASI score was assessed at baseline and monthly follow-up visits along with simultaneous serial digital photographs, with the recording of side effects.

Both groups showed significant decrease in MASI score in each followup visits without any statistically significant difference.

In epidermal melasma topical triple combination is preferred over oral tranexamic acid. In dermal and mixed variety oral tranexamic acid is better.
A study of antifungal susceptibility pattern of dermatophytes at tertiary care center
Authors: Sethi Siddharth , Kumar Ujjwal , Varma Krishnendra , Marothi Yogyata , Pratap Singh Chouhan Mahendra
Published: September 2021

Dermatophytes are fungi that can cause infections of the skin, hair & nails due to their ability to invade keratin. Dermatophytosis is the most common superficial fungal infection worldwide; it is common in tropics and subtropical regions. It may present in epidemic proportions in areas of high humidity

: The present study aimed to identify various species causing dermatophytosis & to determine the invitro susceptibility pattern against commonly used systemic antifungal agents in our tertiary care center.

A total of 149 samples were collected of infected skin, hair and nails in a period of 1 year from January 2020 to December 2020. Samples were collected under aseptic condition by skin scrapping, nail and hair clipping by using scalpel or forceps. Identification of the causative pathogen was done by performing slide culture, lacto-phenol cotton blue mount, hair perforation tests and urease tests. We adopted a newly developed agar based disk diffusion assay to test susceptibility of clinically isolated dermatophytes for antifungal susceptibility testing.

Microbiological investigations revealed the presence of dermatophytic fungi in 71.8% of the samples. Trichophyton rubrum was the predominant pathogen isolated. The study showed Itraconazole to be most effective antifungal drugs against dermatophytes followed by terbinafine and fluconazole.

Further intensive epidemiological and invitro antifungal susceptibility studies of dermatophytes are required which will have more public health significance.
A single arm, exploratory and pilot study to evaluate the efficacy of a multi-component water-based herbal supplement in hair growth, density, follicle strength and hair fall in healthy male and female subjects
Authors: Janaki C.S , Sachdev Mukta , Ritambhara
Published: September 2021

Most available therapeutics to address alopecia are based on singular targets and mechanism of action based on the assumption of sub-classification to reflect morphological or etiological sub-classes such as hereditary vs acquired factors, anti-inflammatory vs. non-inflammatory factors or scarring vs. non-scarring factors.

Impact of oral consumption of Diabliss Hair Water, a multi-component herbal water supplement (HWS) on hair fall reduction, hair growth, hair density, hair thickness was investigated in a single arm, exploratory, pilot open label clinical study among healthy male and female subjects of age group between 35-50 years, with hair fall and hair thinning concerns.

The study was conducted under dermatological control and included hair fall by comb test, hair pull test, hair thinning measurement using photo numerical scale (modified Norwood and Ludwig scale) and assessment for hair quality along with the phototrichogram assessment using Trichoscan® with Cutiscope.

The Diabliss HWS was efficacious in improving hair growth rate and density as per TrichoScan® assessment, improvement in hair thickness as per Caslite-Nova software. The Diabliss HWS was also efficacious in improving the hair tensile strength (break force by Chatillon Force gauge), reducing hair fall and improving the hair quality. By the end of the study the Diabliss HWS was found to show an improvement in the entire study population in all of the assessments parameters. Dermatologist assessment parameters of hair texture and hair shine also showed improvements in the entire study population.

The Diabliss HWS was found to be efficacious in providing hair fall control and hair growth benefits as per the dermatological and instrumental evaluations using TrichoScan®. The product was well tolerated with no product related AE or SAE with regular consumption for 06 months.
A clinicoepidemiological study of familial leprosy
Authors: Kumar N R Dilip , A R Shashikiran , B Horatti Laxmi
Published: September 2021

: Hansen’s disease (also known as leprosy) is an infection caused by Mycobacterium leprae which can affect the skin, mucous membranes and nerves. It is known to spread among and infect family members. There are very few published studies pertaining to family leprosy conducted in India and worldwide.

: To find the prevalence of familial leprosy and to know the clinicoepidemiological patterns of these cases.

: Observational study.

: This was a descriptive study conducted for a period of five years from 2013-2018. The study population included all new documented cases of leprosy visiting our out-patient department during the study period. All the patients were diagnosed as leprosy on histopathological confirmation or by the presence of cardinal signs of leprosy according to the world health organization (WHO) definition. The data collected was analysed by simple descriptive statistics. Permission to conduct the study was taken from institutional ethical committee. Consent was taken from index case and family members.

: A total of 302 new leprosy cases with 18 index cases (n=18) whose family members were affected, accounting for the prevalence of 5.96 %. Total number of family members with documented leprosy (old or newly detected) was 26. So, the total number of leprosy cases were 44 (index cases + family members). Out of the 18 families, 4 families had more than one person who was affected. 8 cases (18.18%) of Childhood leprosy were noted. Among the index cases 4 cases (22%) of paucibacillary leprosy were seen and 14 cases (78%) of multibacillary leprosy was seen. Among the family members, 18 cases of paucibacillary leprosy were seen and 8 cases of multibacillary leprosy were seen. Conjugal leprosy was seen in 10 families accounting for the prevalence of 3.31%.

: Our study intends to emphasize the importance of examining the close contacts of a case of leprosy, especially the family members in whom the incidence of leprosy could be very high. By way of identifying leprosy cases early in its course we may be able to prevent deformities to a great extent.
A rare case report of elastosis perforans serpiginosa in acquired cutis laxa
Authors: Roja R , Pemmaraju Ramanamurthy , V Pasagadugula Krishnarao , N S S Penugonda Raajitha
Published: September 2021

Elastosis perforans serpiginous (EPS) is a rare perforating disorder characterized by trans epidermal elimination of fragmented elastic fibres.The cutaneous features include asymptomatic hyperkeratotic papules. Here we present a case of 27-year old female presented with hyperkeratotic papules with central depression arranged transversely in a serpiginous fashion on front of the laxed skin of the neck region. The histopathological features are consistent with the features of EPS on Cutis Laxa. Elastosis perforans serpiginosa in Acquired cutis laxa has not been reported very rarely, hence this case has been reported.
Dendrimer evolution timeline: Ground-breaking progress in cancer treatment
Authors: Bhattacharya Sankha , Kuwar Utkarsha Chhotulal
Published: September 2021

Dendrimers holds potential in abating restrictions of other available treatments through the development of functionalized particles for targeted treatment. By developing functionalized particles for targeted treatment, dendrimers have the ability to reduce the limitations of other available therapies. Dendrimers have many advantages over other nanoparticles, making them perfect candidates for more efficient and targeted drug delivery. Dendrimers have the ability to deliver vast quantities of drugs to particular locations. They can also be used to monitor the progress of the procedure, giving them a theranostic capability that has never been seen before. Dendrimers show their potential applicability for effective cancer treatment for the near future. These article highlights the evolution timeline of dendrimers and various related aspects of the past four decades. These also involve the basic structure and information of dendrimers along with the current and future perspective. As a result, it is important to study dendrimers in order to keep up with recent developments.
Mucormycosis: A manifestation in COVID-19 infection
Authors: Sharma Abhishek , Bano Gulnaz , Malik Abdul
Published: September 2021

Patients with COVID-19 may develop higher susceptibility to fungal co-infections. Mucormycosis is a rare and often life-threatening disease caused by vascular invasion by hyphae, leading to thrombosis and necrosis. Mucormycosis has been the cause of morbidity and mortality in transplant, ICU and immunodeficient individuals over a long period of time, but in India, a rapid increase in the number of cases seen in unexpected patients with Covid-19, which is a major concern. Covid-19 patients, already immunocompromised with underlying condition, had been exposed to severe Covid-19 infection and been using steroids, were at greater risk of developing mucormycosis. Out of ten cases reported by Sir Ganga Ram Hospital, Delhi India in December2020, five succumbed to mucormycosis. Another unique feature reported in mucor patients was age, most were elderly with ages between 45 to 60 years. The mortality rate is currently estimated at 50% in India. Symptoms such as nasal congestion, swelling of the eye or cheeks and dark brown crusts inside the nose should be reported immediately and anti-fungal treatment should be started.
Anticataract activity of pioglitazone by using in-Vitro goat lens model
Authors: Aware Rinkal R. , Pagar Hemant J. , Barkade Ganesh D. , Dhawane Shweta
Published: September 2021

In the present study we have selected antioxidants agents like Pioglitazone and Ascorbic acid were subjected for anti-cataract activity by in vitro glucose induced cataract model. In the procedure, goat lenses was incubated along with the aqueous humor solution containing 55mM glucose with Enalpril as a standard compound and Pioglitazone with varied concentration for the time interval of 72 hours at room temperature. There was a formation of blur layer on the goat eyeball occurs after 10-12 hours and this process complete after 72 hours. The cataract inducing lenses showing higher level of Na, MDA (P<0.001) along with the decreases in sodium-potassium ATPase activity and water-soluble protein content. The goat lenses treated with Ascorbic acid 40 µg/ml and Pioglitazone in concentrations of 15, 30, and 60 µg/ml showed increased protein content and prevent the formation of cataract.
A study of risk score assessment in antenatal women and their neonatal outcome in a tertiary care hospital
Authors: Kumar Amit , Sindhusha P. , Satyavathi P.J.N. , Pragnasai N. , Deepika P. , Annapoorna S.
Published: September 2021

A high-risk pregnancy is any condition associated with a pregnancy where there is an actual or potential risk to the mother or fetus. Risk assessment is a key component of antenatal care (ANC) and has demonstrated benefits in improving maternal and perinatal outcomes.

To assess maternal complications that occurs in antenatal women and their neonatal outcomes in a tertiary care hospital.

200 antenatal women, admitted to obstetrics & gynaecology department from 16-09-2020 to 15-03-2021 were evaluated. Antenatal women with maternal complications (Gestational hypertension, preeclampsia, Gestational diabetes, Hypothyroid, Anaemia, Asthma and oligohydramnios) were taken into study group and women with no complications were taken into control group. The risk factors were assessed and risk scores were determined by Dutta and Das scoring system and Hobel risk scoring system.

It was found that there was a significant association between poor neonatal outcome and high-risk pregnancies. The incidence of preterm births is higher in the study group (34.1%) when compared with the control group (13.7%). Mode of delivery was predominantly by caesarean section in the study group (p<0.005). Neonatal complications were significantly more (p<0.05) in study group and fetal distress was exclusively seen in the study group (p<0.0005). Maternal complications such as eclampsia correlated significantly with the risk score (p=0.005). Neonatal outcomes such as Low birth weight (p<0.0001) were higher in the high-risk category when compared to the low risk and moderate risk category.

There was a significant correlation between high-risk antenatal and poor neonatal outcome. Scoring systems, such as the one used in our study, can be adopted at primary and rural health centres even by a non-medical counsellor as a screening tool to predict pregnancies at high risk for poor neonatal outcome, thereby facilitating early referral of these women to tertiary care centres.
Formulation and evaluation of herbal gel for management of mouth ulcers
Authors: Upadhye K. , Charde K , Dixit G , Bakhle S
Published: September 2021

: or mouth ulcers is the most common condition that we encounter. Clinically the lesions are single or multiple superficial and deep sealed and are associated with microbial invasions.

: This study was conducted with the aim of evaluating the effectiveness of herbal drugs for treatment of

In the research work, mouth ulcer gels were formulated incorporating the extracts of as and using 934 as the gelling agent. Seven batches were formulated by varying the concentration of the herbal ingredients (F1 to F7)The prepared formulations were evaluated for various parameters like physical appearance, pH, Homogeneity and antimicrobial activity against fungi and bacteria. The antimicrobial activity was also compared with a marketed gel formulation.

All the prepared formulation using different concentration of plant extract showed the pH values in between 6.1±0.2 to 7.0±0.1. The values ranged between the 5.0 to 8.0 cm. Out of all the formulations, formulation F7 containing all the three herbal extracts showed a goodand very promising antimicrobial activity comparable with a marketed gel.

Thus stable, effective gels containing herbal ingredients for management of mouth ulcers can be developed.
Taşkın ve Rüsubat Kontrolünde Yeni Öneri: Gemiburnu Tip Geçirgen Bent
Authors: AKÇALI Emre
Published: September 2021

Dağlık havzalarda ciddi hasarlara ve can kaybına neden olan taşkın olayları, büyük ölçüde taşkın sırasında köprü ve menfezleri tıkayan odunsu malzemenin taşınmasıyla meydana gelmektedir. Son yıllarda, odunsu malzemeleri tuzaklamak üzere geçirgen tersip bentleri inşa edilmeye başlanmıştır. Ancak, bu yapılar özellikle büyük taşkınlarda odunsu malzemelerle kısa sürede tıkanabilmekte, bu nedenle malzeme filtreleme ve odunsu materyali tuzaklama işlevini hızla kaybetmektedir. Bu çalışmada, bu sorunun önlenmesi adına gemiburnu şeklinde tasarlanmış yeni tip bent, işletme halindeki iki farklı tipteki klasik yarı geçirgen tersip bendi ile laboratuvar ortamında karşılaştırılmıştır. Sonuçlar yeni tipin hızlı tıkanma ve üstten aşma sorununa karşı etkili olduğunu göstermiştir. Bu yapının uygulanmasıyla taşkın zararlarının azaltılması adına önemli bir katkı sağlanmış olacaktır.
The socio-cognitive theory of personality and its clinical applications
Authors: Ozga Wioletta Karina
Published: September 2021

Personality is a cognitive-affective processing system, which, according to the socio-cognitive theory, creates four dimensions. They are reflected in the skills, beliefs, standards and goals of the individual, which are consistent and consistent patterns of behaviour.

Self-efficacy judgments and self-patterns determine the choice of goals and persistence in achieving them. On the other hand, the emotions preceding and accompanying the achievement of goals affect coping with stress and problems.

The review of the clinical and therapeutic applications of this theory included stress inoculation training, REBT rational emotive therapy, Beck's cognitive depression therapy, schema therapy and modelling methods. The great advantage of this theory is the possibility of verifying its theoretical assumptions and confirming their huge amount of research.

Besides, it has a practical application as many types of cognitive-behavioural therapies have been developed on its basis.
Evaluation of Doctors’ Knowledge of Rational Laboratory Use, A Descriptive Study From Turkey
Authors: KILIÇ Evrim , KAYHAN TETİK Burcu , KURT Osman
Published: September 2021

Objective: The effects of health expenditures on the economy of countries have become more evident in recent years. Especially unnecessary and inappropriate laboratory tests increase both the cost and the workload. In this study, it was aimed to evaluate the level of knowledge of physicians about rational laboratory use and procedure for frequently ordered tests in clinical practice.

Methods: This study was planned to be a descriptive study. A questionnaire based on the current circular about 'Rational Laboratory Use' and including sociodemographic data was applied to physicians working at Turgut Ozal Medical Center.

Results: The questionnaire was applied to a total of 400 physicians working in internal medicine and surgical branches. The average age of the physicians was 33.01 ± 5.97 (min = 22, max = 59) years. The question about order period of blood lipids was answered correctly by 3.3% of physicians, HbA1c by 80.8%, Urea / creatinine by 64.5%, and vitamin D and vitamin B12 was answered by 40% of physicians. On the other hand 85.3% of the physicians were not aware of the rational laboratory test ordering procedure and 94% had not received any training on rational laboratory use.

Conclusions: It was found that physicians had insufficient knowledge about rational laboratory use and they did not receive any training about the test procedures. In order to reduce health expenditures, more training on this subject should be organized for physicians and awareness should be raised.
The prevalence of multimorbidity among adults aged 40 years and above in primary care setting: a cross-sectional study
Authors: AKTURAN Selçuk , KARAHAN Ömer , AKMAN Mehmet
Published: September 2021

Objective: Coordination function of primary care (PC) enables continuous, efficient, and cost-effective health care provided to patients with chronic disease and multimorbidity (MM). The aim of this study was to identify the most common chronic diseases and to determine the prevalence of MM in PC registries.

Methods: Our study is a cross-sectional study. All the individuals aged 40 and over who were registered to the primary care units (PCUs) of the Uskudar district of Istanbul have formed the population of the study. A systematic cluster sampling was used. The patient list of each family physician in Uskudar district was accepted as a cluster and an equal number of patients from each cluster were enrolled. Only the information on the patients’ MM data was requested from the primary care physicians.

Results: The 108 physicians of the Uskudar district (response rate: 73.4%) gave consent to participate in the study. The 1187 (40.3%) of registered patients of all PCUs were 40 years old and over. The multimorbid patients were found as 330 (27.8%).

Conclusion: Approximately, one of four patients have multimorbidity. So, the policy of primary care services should be redesigned for the management of MM patients including the ‘goal-oriented care’ approach.
Identification of the Gram Positive Bacterial Sepsis Agent with Rapid Genotype Test
Authors: ERDOĞAN Ziya , ÖZTÜRK Cihadiye , CANGÜR Şengül , ÇALIŞKAN Emel , ÖKSÜZ Şükrü , KARAMURAT Zeynep
Published: September 2021

Objective: An irreversible process begins when a systemic infection causes sepsis. Therefore, rapid identification of the agent bacteria in sepsis and its antibiotic resistance is crucially important. In this study, it was aimed to investigate the efficiency of rapid genotype test.

Methods: Blood culture bottles sent to the laboratory were examined with an automatic blood culture system (BACTEC, BD, USA). Growing bacteria was identificated by VİTEK (bioMérieux, France) automated bacteria identification / antibiotic susceptibility system. In addition, bacterial species and mecA, vanA, vanB, vanC1, vanC2 / C3 genes in blood cultures with Gram positive bacterial growth were also determined by the "Genotype® BC Gram-positive (Hain Lifesience, Germany)" test.

Results: 72 patients with gram-positive bacteria growth in two or more blood culture bottles were included in the study. In 44 of the samples (61%) the same bacterial species were detected with conventional method (bacteria culture) and BC Gram positive test. In 28 of the samples (39%) differences were detected between results of methods regarding bacterial species name or vancomycin/methicillin resistance rate. Although single agent was isolated with culture method in all of the samples, multiple agents were detected in eight samples with rapid genotype test. Also, it was found that in mecA positive samples, ciprofloxacin resistance was higher than mecA negative ones.

Conclusion: In the study, it was observed that BC Gram positive test could correctly identify sepsis agent bacteria and their resistance genes within 4-5 hours.
Impact of Rational Laboratory Practice on Hospital Procedure Costs Based on Evidence-Based Medicine: Case Study In A University Hospital
Authors: KAPLAN Zekeriya , BOZDEMİR Enver
Published: September 2021

Objective: By integrating the rational laboratory system into hospital processes with evidencebased medicine applications, it is ensured that hospital resources are used more effectively and

efficiently by preventing unnecessary test requests and reducing laboratory operation costs.

Methods: The data in this qualitative study are the primary data and were obtained through

document review and focus group (physician) interviews. The data in question were analyzed

comparatively before the Rational Laboratory Application (RLA) (between 01.06.2018-

31.12.2018) and after the RLA (between 01.06.2019-31.12.2019). The universe of the study

consists of all the data in the laboratory of Düzce University Health Application and Research

Center Hospital (DUHARCH). In this universe, the data evaluated for rational laboratory

application constitute the sample of the research.

Results: Before the RLA, a total of 446,300 test requests were made in the seven months (in

2018) and the cost of these tests was determined to be 1,591,063 ₺ ($ 330,782.33). After the

RLA, a total of 475,585 test requests were made in the seven months (in 2019), and the cost of

these tests was determined to be 1,537,903 ₺ ($ 271,235.10). It was found that after RLA, there

was a 6.56% increase in the number of examination requests compared to before RLA, but as an

amount, costs fell by 3.34% on a ₺ basis and 22% on a $ basis. In the unit-based analysis, it was

seen that successful units were surgical, and unsuccessful units were internal units that requested

more tests.

Conclusions: It was concluded that the rational laboratory system based on evidence-based

medicine reduces hospital processing costs, provided that patient safety is protected, so this

method can be a tool for more effective and efficient use of hospital resources.
A Comparison of the Effectiveness of Hypnotherapy and Cognitive Behavioral Therapy in the Treatment of Primary Vaginismus
Authors: TAŞTAN Kenan , YORUK Nurcan , IŞIK Memet
Published: September 2021

Objective: This study compared the therapeutic effectiveness of hypnotherapy and cognitive behavioral therapy in patients with primary vaginismus previously assessed by a psychiatrist and a gynecologist

Methods: We performed as a single-center, cross-sectional study in 35 patients with primary vaginismus

Results: Successful coitus was achieved by 19 (95%) individuals in the hypnotherapy group and by 14 (93.3%) members of the cognitive behavioral therapy group. These success rates were similar (p=0.681). The mean number of sessions until successful coitus was significantly lower in the hypnotherapy group (p=0.000).

Conclusions: hypnotherapy and cognitive behavioral therapy can be applied with similar high success rates in the treatment of vaginismus. However, success may be achieved with fewer sessions with hypnotherapy.
Evaluation of Adaptation to Guidelines on the Management of Chronic Obstructive Pulmonary Diseases in Family Medicine
Authors: ODABAŞ Öznur Kübra , DOĞAN Deniz , YILMAZ Tarık Eren , ÖZKARA Adem
Published: September 2021

Objective: Chronic Obstructive Pulmonary Disease (COPD) has become increasingly important in recent years. The CAT (COPD Assessment Test) and mMRC (Modified British Medical Research Council) scales can be used in the clinical evaluation of the patients according to GOLD the COPD Protection Diagnosis and Treatment Guideline guideline. Patients were divided into groups A, B, C and D using the scales with the combined assessment scheme proposed by GOLD, and recommended treatment scheme for each step is determined. In this study, it is planned to investigate whether COPD patients getting the optimal treatment according to GOLD guideline. It is also aimed to expand the use of these scales in Family Medicine practice, which helps understanding the clinical status of patients.

Method: This is a descriptive, cross-sectional study. 218 patients were included in the study. The questionnaire form of the study was applied to the patients and the patients were evaluated and scored with the help of these scales. Statistical analysis of the data obtained in this way was done by the SPSS program.

Result: According to the CAT result, compliance with the guideline was 8.4% in group A, 22.3% in group B, 5.8% in group C and 77% in group D. In the evaluation made according to the mMRC result, compliance with the guideline was 12.5% in group A, 24.7% in group B, 0% in group C, and 77.7% in group D. It was determined that only 40.8% of patients according to mMRC and only 33% according to CAT were receiving the optimal treatment that was completely suitable for their groups.

Conclusion: Patients with stable COPD had significantly higher use of bronchodilator drugs than recommended. The use of this scale by Family Doctors, will be important in determining the needs for treatment and COPD patients follow-up.
Possibilities of using leaves cultivated chicory (Cichorium intybus L.) as a medicinal plant material (review)
Authors: Mavrina P. O. , Saybel O. L. , Malankina E. L.
Published: September 2021

Common chicory (Cichorium intybus L.) is widely known as a food plant. However, in folk medicine in many countries, the roots and leaves of chicory are used as a choleretic, anti-inflammatory, hypoglycemic agent. In this regard, a promising direction of research is a detailed study of the biological characteristics and chemical composition of this plant in order to substantiate its use for therapeutic and prophylactic purposes. The article presents an analysis of the available information on the botanical classification and biological characteristics, agricultural technology, chemical composition and the use of the aerial part of the cultivated common chicory in scientific and folk medicine. Possible resources for collecting chicory leaves are wild-growing populations, as well as varieties of root chicory, which is grown in Russia as an industrial crop. Under natural conditions, chicory occupies disturbed habitats characterized by low soil fertility, pollution with heavy metals, and increased competition with other ruderal plants. While in the conditions of culture, the best agroecological conditions for growing plants are provided, accelerating their development and contributing to accumulation of biologically active substances in greater quantities, compared with wild ones. In this regard, a promising direction of research is to study the influence of various factors (illumination, temperature, weather conditions, agrotechnical measures, varietal characteristics, growth regulators) on the content, qualitative composition and dynamics of the accumulation of biologically active compounds in the leaves of cultivated common chicory.