bluuebunny/crossref_metadata_2025 huggingface dataset:
Normal saline infiltration as a treatment of steroid injection induced tissue atrophy: A clinical study
Authors: Biswas Rabindranath , Sarkar Dibyajyoti , Ghoshal Loknath
Published: November 2023

Introduction and Aim: Intramuscular steroid injection is a technique often used by unqualified village practitioners to control symptoms of a variety of disease processes. Such injudicious use of high dosages of steroids results in local side effects. Such side effects include occurrence of tissue atrophy at the site of injection. The treatment of such tissue atrophy includes filling up the gap with injection of autologous fat and other materials. However, these are expensive and require specialised set up. Normal saline infiltration into the atrophic area at varying intervals has been successfully tried by several authors in the past. The aim of the study was to find the efficiency and side effects of normal saline infiltration into acquired lipoatrophy areas as a method of treatment.
 
Material and Methods: After informed consent, normal saline was infiltrated into the defect till sufficient tumescence was obtained.
 
Results: Nine children were treated. Most of them had received steroid injections for exacerbation of childhood asthma. The defect had appeared shortly (2 to 4 months) after the last injection was received. The site of the defect was rounded and located on the deltoid region in the majority. Our success rate was 66%. The determination of the success rate of this technique and the factors contributing to the success of the technique requires more studies in this field.
 
Conclusion: Normal saline infiltration is a safe and effective way for treating steroid injection induced skin and tissue atrophy.
Prevalence of target organ disease and its relation with HbA1c at the point of detection of type 2 diabetes mellitus – A cross sectional study from a tertiary care hospital in Odisha
Authors: Elika Manasa , Kabi Sobhitendu , Dash Abhishek Prasad , Sahu Samir , Kumbha Gopi , Jonnalagadda Vihari , Bhargav Vamsi Krishna Yargarla , V S R S L Aneesh Kalavakolanu , Jain Abhik , Veneeth Varma Tirumalaraju
Published: November 2023

Introduction and Aim: HbA1c is not only a valid indicator of chronic hyperglycaemia but also coincides with the increased risk of diabetic complications in the long term. This study focuses on the prevalence of target organ disease (TOD) and its relation with HbA1c at the point of detecting Type 2 Diabetes Mellitus(T2DM).
 
Materials and Methods: This is a single-centre cross-sectional study done in the Department of General medicine at IMS and SUM Hospital, Odisha, between November 2020 and June 2022, including all newly diagnosed Type-2 Diabetes Mellitus patients aged > 30 years. Besides all the biochemical parameters, the demographic profile was noted in an excel sheet, and later on, using SPSS version 26, the data was analysed categorically.
 
Results: 148 newly diagnosed Type 2 DM patients were enrolled in the study with male predominance (54.72%). The mean age was found as 52.49±9.40 years. There were 29 (19.5%) cases of diabetic retinopathy, 39 (26.3%) diabetic neuropathy, 32(21.6%) diabetic nephropathy and 23(15.54%) left ventricular diastolic dysfunction, with a minimal number of RWMA [7 (4.72%)], Concentric left ventricular hypertrophy [9 (6.08%)] and Ischemic DCM [1(0.67%)] found as complications of newly diagnosed Diabetes mellitus patients. The prevalence of coronary artery disease (CAD) is higher in our study than in other diabetic complications, i.e., 40 (27.02%).A statistically significant (p<0.05) correlation exists between newly diagnosed Diabetes patients with higher HbA1C and serum creatinine, serum urea, microalbuminuria, and positive monofilament test.
 
Conclusion: This study underscores the significance of assessing target organ damage (TOD) prevalence for Type 2 Diabetes Mellitus (T2DM) detection, highlighting the utility of HbA1c testing. HbA1c, a rapid and precise diagnostic tool, holds promise, especially in resource-limited settings, aiding in timely T2DM diagnosis and improved patient care amid the global diabetes epidemic.
Serum microRNAs dysregulation in cervical cancer and their diagnostic role: A systematic review
Authors: Abbas Hussein Hameed , Edwin Rodrigues Fenwick Antony , Ramasamy Sivasamy
Published: November 2023

Cervical cancer is the fourth-highest prevalent tumor among women in the world. Though the development in the early diagnosis of cervical cancer in developed countries, developing countries are still suffering from it. Among the different biomarkers, serum microRNAs (miRNAs) were reported as valuable tools in the diagnosis of cervical cancer. To highlight the most recent studies of the serum miRNAs in cervical cancer diagnosis, we systematically searched science direct and Web of Science databases using keywords, and the articles that meet inclusion criteria and do not meet exclusion criteria are included in the current review for further analysis. After applying the current study inclusion and exclusion criteria we found 42 dysregulated miRNAs, among them miR-21 was the most investigated, and most of them were capable of distinguishing between healthy and cervical cancer subjects. The current study shows the importance of serum miRNAs as biomarkers in cervical cancer diagnosis.
Isolation and characterization of an antibacterial compound Bis-(2-ethylhexyl) phthalate from the fungi Penicillium digitatum
Authors: A. Abd Ali Mohammed , O. Darweesh Asaad , M. Matar Muthanna
Published: November 2023

Introduction and Aim: Penicillium is a fungal antibiotic derived from Penicillium notatum. In this study, we aimed to isolate the antibacterial compound Bis-(2-ethylhexyl) phthalate from the fungi Penicillium digitatum, as well as study its antibacterial activity against the the pathogens Escherichia coli,Group B Streptococcus agalactiae, and Staphylococcus aureus.  
 
Materials and Methods: The identification of Bis-(2-ethylhexyl) phthalate-containing secondary metabolite was achieved through bioassay-guided chemical analysis of the crude extract. The structure of the compound was identified from UV spectra, IR, and GC-MS spectral data. The antimicrobial activity of Bis-(2-ethylhexyl) phthalate, isolated from the fungus Penicillium digitatum, was determined using standard methods.
 
Results: UV, IR, and GC-MS spectroscopy confirmed the crude extract of fungi Penicillium digitatum to contain the bioactive compounds 1,2-benzenedicarboxylic acid and bis(ethylhexyl) phthalate. The MIC value of the bioactive molecule was also determined to be 32 mg/ml. The P. digitatum ethyl acetate extract showed moderate antibacterial activity against the Gram-negative bacterial isolate Escherichia coli and high activity against the Gram positive pathogens Streptococcus agalactiae and Staphylococcus aureus.
 
Conclusion:  The fungi Penicillium digitatum produces the metabolite Bis-(2-ethylhexyl) phthalate, which exhibits antibacterial activity against Gram positive and Gram-negative pathogens and hence could be used in treating infections by these bacterial pathogens.
Salivary calcium in postmenopausal women and prevalence of dental caries: A cross sectional study
Authors: Shetty Nireeksha , N. Hegde Mithra , Rai Manisha , Rama Varma Sudhir
Published: November 2023

Introduction and Aim: Hormonal variations in postmenopausal women may cause growth and development of the oral epithelium, especially in response to estrogen levels. One of the manifestations of this issue is xerostomia or dryness of the mouth. Saliva provides a first line of defence against diseases like caries by maintaining the pH levels. However, estrogen levels have been shown to directly affect the salivary flow rate.
 
Materials and Methods: The current study focuses on the estimation of salivary calcium levels in postmenopausal women and its association with the prevalence of dental caries. Informed consent was obtained from study subjects and they were categorized into case and control based on DMFT index (Decay, filled, missing) WHO criteria 2013.Post menopausal women with caries were categorized has case(n=40) and women who have not attained menopause free of caries were categorized has control (n=40). Unstimulated salivary samples were collected by Navazesh protocol and the salivary calcium levels were estimated by ARSENAZO method.
 
Results: The average calcium levels in saliva were found to be 1.84± 0.30 and 1.67± 0.32 for case group and control group respectively. The   mean decayed, missing due to caries, and filled teeth (DMFT) score was observed to be 10.45± 3.81 and 1.80± 0.341 for case group and control group respectively.
 
Conclusion: According to the findings, postmenopausal women need to be administered enough calcium supplements in order to maintain good dental hygiene and thus improve lifestyle.
In vitro anticancer activity of Citrus maxima peel extract on human breast cancer cells
Authors: Monteiro Flama , S. Shetty Shilpa , Acharya Ranjitha , Vittal Shetty Vijith , Kumari N. Suchetha
Published: November 2023

Introduction and Aim: The alarming rise in breast cancer cases highlights the need for a safer, effective, and more responsive chemoprevention approach for cancer treatment. In contrast to conventional chemotherapeutic medicines, which primarily function as mono-target agents, phytochemicals have been proven to inhibit cancer growth by influencing numerous processes, such as apoptosis and signaling pathways. Citrus maxima (Burm). Merr., frequently identified as pomelo, exhibits a wide range of biological activities, and is utilized extensively in the conventional approach to medicine, and this study focused on anti-cancer properties of Citrus maxima peel extracts.
 
Materials and Methods: The anti-proliferative properties of the Citrus maxima peel extracts and its flavonoid Naringin on the breast cancer cell line was evaluated using the MTT test. The ability of the breast cancer cells to migrate was assessed using a wound healing assay and their capacity to form colonies was assessed using a colony formation assay.
 
Results: The Citrus maxima crude peel extracts and Naringin inhibited the cell proliferation of the breast cancer cell line. The cell viability of breast cancer cells decreased with time after treatment with their corresponding IC50. The colony-formation capacity and migration ability of the cells was also reduced.
 
Conclusion: The examined Citrus maxima crude peel extracts and its flavonoid Naringin showed strong anticancer efficacy by suppressing cell proliferation and could be seen as prospective candidates for upcoming breast cancer therapeutic medications. Extensive research is also needed to fully comprehend the precise mechanism of action of extracts and its components.
Anti-cancer potential of Lactiplantibacillus plantarum NG28 through the induction of intrinsic apoptosis
Authors: Shankar Sowmya , Jayarama Shankar , Gopal Shubha
Published: November 2023

Introduction: Probiotics and fermented foods have become the focal point of research across different scientific disciplines, with recent findings indicating that Lactiplantibacillus plantarum (L. plantarum) isolated from various origins, holds significant promise in combating numerous diseases, including cancer. Hence, our current study seeks to explore how the L. plantarum NG28 strain might counteract the growth of HT-29 colorectal adenocarcinoma cells, potentially contributing to anti-cancer strategies.

 

Methods: The effect of the ethyl acetate extract of L. plantarum NG28 strain on HT-29 cells was evaluated in several ways. First, the cytotoxicity of HT-29 cells was determined by MTT assay. Additionally, the changes in cell morphology of HT-29 cells through DAPI staining and the induction of apoptosis using Annexin V-FITC/PI staining followed by flow cytometry were investigated. By using the RT-PCR and western blot techniques the expression of pro-apoptotic genes and proteins such as Bax, Caspase-9, and Caspase-3, as well as the anti-apoptotic gene Bcl-2 was examined.

 

Results: The findings revealed that the ethyl acetate extract of L. plantarum NG28 strain had a significant impact on the viability of HT-29 colon cancer cells in a dose-dependent manner, in contrast to its minimal effect on HUVEC cells. DAPI staining revealed the noticeable DNA damage and condensation of treated HT-29 cells and the flow cytometry strengthened the occurrence of apoptosis in the treated HT-29 cells. RT-PCR and western blot techniques investigated the intrinsic apoptosis of HT-29 cells through the increased expression levels of pro-apoptotic genes / proteins and decreased expression levels of anti-apoptotic gene.

                                                                                                                                                                                                                                                                    

Conclusion: The study demonstrated the anti-cancer activity of ethyl acetate extract of the L. plantarum NG28 strain against HT-29 colon cancer cells, primarily through the intrinsic apoptotic pathway. This suggests that L. plantarum NG28 strain could be used as a therapeutic tool in the inhibition and medication of colorectal cancer.
Lectura e interpretación de las cuentas anuales consolidadas
Authors: Gonzalo Angulo José Antonio
Published: November 2023

El propósito de este trabajo es el tratamiento en detalle del contenido y movimiento de las cuentas que son específicas de los estados consolidados, esto es, que por derivarse directamente del proceso de consolidación se inscriben en el balance o la cuenta de pérdidas y ganancias consolidada, sin tener relación directa con las correspondientes a los estados contables individuales de las empresas.
No se trata de un trabajo de investigación sobre el significado de las citadas cuentas, sino un simple recorrido por lo que se podría llamar el «plan de cuentas de la consolidación», pasando revista a las cuentas que aparecen en el proceso, escudriñando su concepto, contenido, movimientos, significado de su saldo y colocación en los estados contables correspondientes. Como introducción, se realiza también un breve bosquejo histórico de la normativa de la consolidación en España y se describe la obligación de presentar cuentas consolidadas, así como la tipología de empresas implicadas en los estados financieros en base consolidada.
Tanto los artículos 42 a 49 (Sección Tercera del Libro I) del Código de Comercio, redactados según la Ley 19/1989, de 25 de julio, que se refieren a la presentación de las cuentas de los grupos de sociedades, como su desarrollo reglamentario, contenido en el Real Decreto 1815/1991, de 20 de diciembre, donde se recogen las Normas para la formulación de cuentas anuales consolidadas (en adelante Normas de consolidación del Instituto de Contabilidad y Auditoría de Cuentas, ICAC), exponen la consolidación siguiendo un orden lógico de confección: Sujetos de la consolidación, obligación de consolidar, método de integración global, método de integración proporcional y puesta en equivalencia y cuentas anuales consolidadas.
Incrementos y disminuciones de patrimonio
Authors: Sanz Gadea Eduardo
Published: November 2023

Una vez establecido por el artículo 44 el concepto de incremento o disminución de patrimonio, los artículos 45, 46, 47 y 48 se ocupan de la determinación de su importe. Podemos distinguir tres aspectos o materias dentro de la regulación establecida por los artículos citados:
– Reglas de cálculo generales: Artículos 45, uno, 46 y 47.– Reglas de cálculo especiales: Artículo 48.– Reglas relativas a los incrementos de patrimonio a largo plazo: Artículo 45, dos y tres.
De los tres bloques de materias, el señalado en tercer lugar encierra una novedad de largo alcance pues en él se contiene el pronunciamiento del legislador sobre una materia tan delicada como son las ganancias del capital. Es verdad que las ganancias de capital afectan a pocas personas, pero también lo es que estas personas suelen ser las de más elevada capacidad económica porque, obviamente, para tener ganancias de capital hay que disponer previamente de capital.
Lectura e interpretación de las cuentas anuales consolidadas (II)
Authors: Gonzalo Angulo José Antonio
Published: November 2023

Aunque comentando las cuentas específicas del balance consolidado surgen, en general, los comentarios referentes a gastos e ingresos consolidados, parece adecuado profundizar algo más sobre los mismos con apartados más concretos donde se comenten y se ofrezcan ejemplos a modo de glosa.
Como en los estados financieros individuales, las Normas de consolidación del ICAC han optado por el formato de cuenta para la de pérdidas y ganancias, no instando a los grupos -como se hacía en el Plan contable- a presentar siquiera una cuenta analítica, que hubiera sido más fácil de leer y entender para los usuarios menos expertos.
A los efectos de seguir con más comodidad la exposición que sigue, se han reproducido los principales componentes de gastos, ingresos y resultados del formato de la cuenta de resultados consolidada, elaborado para mejor comprensión, en el esquema IX.
Incapacidad laboral transitoria
Authors: Verdera Ribas Francisco
Published: November 2023

El objeto de este trabajo es unir en una sola obra la gran cantidad de leyes, decretos, ordenes ministeriales, jurisprudencia, etc. que hay sobre incapacidad laboral transitoria; además de este objetivo principal, se ha tratado de darle un enfoque práctico, en el que se analizan las diversas situaciones a través de la experiencia de una Asesoría Laboral.
La sucesión de empresas
Authors: Tapia Hermida Antonio
Published: November 2023

La transmisión de una empresa constituye, hoy en día, un fenómeno frecuente, que plantea una importante problemática y provoca una gran litigiosidad, de extraordinaria trascendencia práctica, por su afectación a conjuntos enteros de trabajadores.
La regulación por el Derecho del Trabajo de la denominada, en el ámbito laboral, «sucesión de empresas», tiene una extraordinaria importancia por cuanto afecta a la relación laboral individual, con trascendencia colectiva, e influye, en ocasiones de manera de terminante, en la circulación en el tráfico de bienes de muy diversa naturaleza, y por ello tiene repercusiones en ámbitos externos al propio del Derecho del Trabajo, pudiéndose afirmar que aquella regulación laboral tiene consecuencias en todo el ámbito del Derecho privado, especial-mente en el que es propio del Derecho Mercantil, afectando a sectores de éste especialmente dinámicos y sensibles como es el referente al mercado de valores.
Novedades laborales y de Seguridad Social de la Ley de Presupuestos Generales del Estado para 1993
Authors: Cavas Martínez Faustino
Published: November 2023

Como es suficientemente conocido, las Leyes de Presupuestos Generales del Estado (en adelante, LPGE) vienen regulando, desde hace dos décadas y de modo creciente, cuestiones laborales y de Seguridad Social, que afectan tanto al personal funcionarial y estatutario como a los trabajadores por cuenta ajena de las Administraciones Pública. Este dato obliga al laboralista a tener que rastrear atentamente el contenido de dichas leyes (disposiciones adicionales, transitorias y derogatorias incluidas), a fin de detectar los preceptos que inciden, directa o indirectamente, en materias de su especialidad.
La contratación laboral en el derecho español
Authors: Del Val y de la Fuente Eustasio
Published: November 2023

Según ALONSO OLEA, «la crisis económica actual es una crisis de escasez o falta de trabajo en relación con las personas dispuestas a trabajar».
El fenómeno del trabajo como «bien económico escaso» está dando lugar a que sea cuestionada la adecuación del marco jurídico laboral con la realidad social.
Hay que tener presente que los fenómenos sociales preceden a la norma positiva, y que ésta -aun la dictada con vocación de permanencia- debe experimentar frecuentes innovaciones para acomodarse a la realidad sobre la que incide. De ahí que la actividad normativa nunca haya de entenderse ultimada.
Delimitación conceptual y tendencias actuales en la regulación del cierre patronal
Authors: Salmón Gárate Elizabeth , Boza Pro Guillermo
Published: November 2023

El conflicto, entendido en el sentido de discrepancia de intereses que entran en colisión, se presenta como característica inherente y marco permanente de la actuación del Derecho del Trabajo, dado que el trabajo humano ha constituido desde siempre una «fuente de conflictos sociales». El rol del Derecho, en este contexto, ha sido principalmente de cana- lizar, encauzar o integrar (difícilmente eliminar) el conflicto a fin de evitar que las tensiones que produce puedan trastocar el normal desenvolvimiento de la convivencia humana. Precisamente, entre otras, la razón del Derecho del Trabajo ha sido la de evitar que el conflicto socio-laboral desborde el orden establecido.
El conflicto colectivo de trabajo cuenta con dos elementos definidores que lo hacen particular dentro del marco del conflicto laboral: uno que alude al carácter colectivo de los sujetos y, otro, cualitativo, que se refiere al interés colectivo de clase, categoría o grupo. La medida conflictiva, como manifestación abierta de aquél, es todo medio de presión unilateral utilizado por los sujetos en conflicto con el fin de propiciar una solución favorable a sus propios intereses. Tal es el caso, principalmente, de la huelga, del lado de los trabajadores, o del cierre patronal, del de los empresarios, amén de una amplia gama de instrumentos.
Minusválidos: integración laboral y prestaciones socioeconómicas
Authors: García González José
Published: November 2023

La realización del presente trabajo tiene por objeto ofrecer al lector una visión generalizada de la amplia y a la vez dispersa normativa vigente, aplicable al colectivo de personas con minusvalías, dentro del ámbito al que se extiende el Derecho del Trabajo y Seguridad Social.
La pretensión que se persigue, dada la escasez de publicaciones que traten íntegramente desde un punto de vista jurídico-social las diversas situaciones que se puedan plantear, y que de hecho se nos plantean a quienes profesionalmente trabajamos en el ámbito del que este estudio es objeto y a aquellas personas a las que directamente nos afecta el hecho de padecer algún tipo de minusvalía, así como a quienes forman parte de su entorno familiar que con frecuencia se ven obligadas a representarlas, no es otra que contribuir a aportar una mayor claridad, sobre el conjunto de beneficios que el Derecho del Trabajo y Seguridad Social ofrece y que en muchas ocasiones, por la excesiva dispersión normativa, por las propias peculiaridades del colectivo, e incluso del entorno sociofamiliar en el que interaccionan y por qué no, también por el desconocimiento de la sociedad en general, impiden un óptimo aprovechamiento de los mismos y la mayor eficacia de las diversas medidas integradoras.
Kinematic analysis of sway motions of elite dance sport competitors
Authors: Kulis Szymon , Chren Matej , Gajewski Jan
Published: November 2023

Purpose: This study aimed to identify the potential relationship between scores given by judges and kinematic variables used to characterise the sway movement in the Viennese waltz as performed by dance sport athletes. Methods: The study involved six world-class and six intermediate dance couples. The pairs were asked to perform three identical series of three natural spins of the figure in a Viennese waltz and were all recorded by camera as they danced to music. Six international adjudicators evaluated all trials of each couple from the viewpoint of the technical quality component based on the Absolute Judging System. A triaxial rotational angular velocity measurement device
(gyroscope) was placed on the dorsal part of the pelvic girdle and on the posterior part of the thorax of every athlete. Results: The analysis of covariance showed that maximum angular rotation velocities of the thoracic spine in forward sway movements (in the transverse plane) in male dancers were strongly associated with the judging score obtained (F1,9 = 11.5; P < .05; ηp 2 = .05) regardless of the assignment to the given group. Conclusion: According to the study conducted and a comparison of elite and intermediate level athletes, the proposed method of assessing, presenting and reviewing the movement profile of the pelvic girdle and thoracic movement is likely to
become useful for the overall assessment of movement technique, and also for carrying out quick and effective qualitative and quantitative biomechanical assessment of selected components of movement technique in dance sport.
Keywords: Standard style, technique, ballroom dancing, Viennese waltz, absolute judging system.
Challenges faced by male parolees in Lamontville eThekwini Municipality, KwaZulu-Natal
Authors:   , Mngoma Lungile Goodness
Published: November 2023

The South African Department of Correctional Services has a strategic outcome oriented goal of ensuring that parolees (and probationers) are successfully reintegrated into society as law-abiding citizens through the provision of rehabilitation and social reintegration programs. However, the Correctional Supervision and Parole Board (CSPB) is experiencing, and continuously has to deal with, what is referred to as ‘Parole Violators’ - those that have violated their Parole conditions and/or absconded. This study sought to evaluate the experiences and challenges faced by the male parolees of Lamontville in eThekwini Municipality, South Africa, and to improve educational programs to bring about more effective policies. The study focused on male parolees in the Lamontville Community, Durban, South Africa. However, the study sample included both parolees and community members who have a role to play in the reintegration process of the parolees. A qualitative research design, and a Participatory Action Research approach, was employed to provide a comprehensive perspective on the challenges and experiences of male parolees in the Lamontville community. In-depth interviews, focus group discussions, and participant observation, with 10 parolees and 7 community members were used to collect data during the exploratory phase of the study. Further, the Lamontville community building workshop was organized among 10 parolees and 6 community members as part of the action research design. Thematic analysis was used in this study to analyse data collected from participants. While interpreting what was being said and giving evidence to support these interpretations, the researcher was able to identify new patterns, code them and generate themes. The study discovered that the primary challenges faced by parolees in the Lamontville community include unemployment, a broken relationship with family and community members, marginalization, and adjusting to a changing environment outside the correctional service centre. The research then suggests that to address these challenges, there is a need for community awareness and participation in the parolee rehabilitation process, and support groups for the parolees are necessary. Lastly, during the community building workshop, it was suggested that a committee will, going forward, assist the parolees with more harmonious and productive reintegration into the community.
Analisis Performansi Jaringan Komputer Menggunakan Metode Unequal Load Balance Pada Jaringan Lokal
Authors: Putri Agustyaningsih  , Cahyo Prihantoro  , Iqsyahiro Kresna A
Published: November 2023

Salah satu kendala jaringan yang perlu diwaspadai adalah putusnya jalur koneksi yang menyebabkan jaringan sama sekali tidak dapat melakukan pengiriman data. Untuk mengatasi hal tersebut, dilakukan teknik load balance dengan metode unequal load balance. Dengan metode unequal load balance selain untuk mengantisipasi koneksi terputus, teknik ini juga dapat meringankan beban traffic karena tidak hanya satu jalur yang akan menopang traffic jaringan komputer. Penerapan unequal load balance dilakukan secara simulasi pada emulator network GNS3 pada jaringan lokal dengan menggunakan router cisco 7200  sebanyak 8 buah yang terbagi menjadi empat jalur untuk mencapai router tujuan. Adapun hasil pengukuran Quality of Service (QoS) pada unequal load balance yaitu throughput sebesar 2105,832 Kbps dan masuk pada kategori througput yang sangat bagus, untuk delay sebesar 0,0042640 ms dan masuk pada kategori delay yang sangat bagus, untuk jitter sebesar 0,0000003769 ms masuk pada kategori jitter yang sangat bagus, serta untuk packet loss yaitu 0% sehingga masuk pada kategori packet loss yang sangat bagus. Hasil delay perpindahan link sebelum unequal load balance berpengaruh pada link/jalur mana yang diputus, apakah link pada jalur utama atau link pada jalur cadangan yang di putus. Sedangkan hasil delay perpindahan link sesudah unequal load balance tidak berpengaruh dengan jalur mana yang diputus.
Analisis Sentimen Publik Terhadap Aksi Demonstrasi di Indonesia Menggunakan Support Vector Machine Dan Random Forest
Authors: Ni Made Tara Okta Adriana  , I Made Agus Dwi Suarjaya  , Dwi Putra Githa
Published: November 2023

Indonesia adalah sebuah negara demokrasi yang memberikan kebebasan bagi setiap warganya untuk berekspresi dan mengeluarkan pendapat, salah satunya melalui demonstrasi. Namun, kadang kala kebebasan tersebut disalahgunakan oleh pihak-pihak tertentu yang menyebabkan adanya demonstrasi yang diikuti oleh kerusuhan dan aksi anarkis, sehingga menimbulkan berbagai macam kerugian. Penelitian ini bertujuan untuk mengetahui pandangan masyarakat terkait aksi demonstrasi yang terjadi di Indonesia melalui tweets pada media sosial Twitter dengan menggunakan algoritma Support Vector Machine (SVM) dan Random Forest. Pada penelitian ini terdapat penambahan proses untuk menghilangkan kata-kata yang tidak terdaftar pada Kamus Besar Bahasa Indonesia (KBBI) karena tweets pada media sosial Twitter cenderung lebih banyak menggunakan bahasa gaul atau bahasa yang tidak baku, sehingga penambahan proses ini diharapkan dapat memberikan data bersih yang lebih baik. Klasifikasi pada penelitian ini dibagi menjadi 3 kelas, yaitu positif, negatif, dan netral. Pengujian yang telah dilakukan mendapatkan nilai akurasi paling baik dengan menggunakan algoritma SVM, yaitu sebesar 80,3%. Hasil klasifikasi menunjukkan bahwa sebesar 54,98% atau sekitar 960.519 data merupakan klasifikasi negatif yang diikuti oleh sentimen netral sebanyak 29,15% dan sentimen positif sebesar 15,86%.
Tiktok As a Media Application for Improving the Student Speaking Skills
Authors: Gunawan  , Taslim  , Dewi Sartika
Published: November 2023

This research reports on the study of students' speaking ability through the use of the TikTok application. The problem of this research was the improvement of the students’ speaking accuracy and fluency through the use of the TikTok application at SMA Negeri 13 Bone. The purpose of the study was to determine students' ability to speak through the use of the TikTok application. The researcher used classroom action research (CAR), which was conducted in two cycles; each cycle consisted of four meetings. Thirty students in the eleventh grade at SMAN 13 Bone participated in this study The techniques for collecting data were observation and speaking tests. The research findings indicated that the application of the TikTok application was significant in improving the students’ speaking skills in terms of fluency and accuracy. It was proved by the mean score in the speaking ability for DT of 50.7, C1 of 65.79, and C2 of 77.69. So the improvement of the student's speaking ability from DT to C1 is 30.11%, DT to C2 is 52.96%, and CI to C2 is 18.08%. The researcher suggests that the use of media in language learning, particularly for speaking students, is absolutely essential. The TikTok media application is one that must be used. Students respond positively and enjoyably to the use of social media in the language learning process.
Metode Real-Time Berbasis Android Dalam Membangun Sistem Monitoring Kualitas Udara Untuk Proses Sanitasi Rumah Sakit
Authors: Andi Rozzi Yoli , Jhoanne Fredricka  , Estu Putri Arimi
Published: November 2023

Rumah Sakit merupakan salah satu fasilitas kesehatan perorangan yang dapat difungsikan sebagai penyelengggara pelayanan kesehatan bagi masyarakat. Maka dari itu kualitas udara ruang kegiatan yang terdapat di Rumah Sakit merupakan salah satu faktor penting dalam menjaga kesehatan sanitasi Rumah Sakit. Standar baku mutu parameter fisik untuk menjamin kualitas udara ruangan tidak hanya berdasarkan parameter suhu, kelembaban, pencahayaan, namun juga memperhatikan kandungan gas pencemar udara yang paling dominan mempengaruhi kesehatan manusia seperti Carbon Monoksida (CO) / Carbon Dioksida (CO2). Sistem akan memberikan hasil pengawasan pembacaan data secara real-time serta dapat diakses kapanpun dan di mana saja. Penelitian ini memiliki tujuan untuk membangun sistem monitoring kondisi kualiatas udara dengan metode real-time berbasis Android dalam mendukung proses sanitasi lingkungan Rumah Sakit. Hasil pengujian menunjukan bahwa sistem monitoring kualitas udara telah berfungsi dengan baik ditandai dengan sistem dapat menampilkan data suhu, kelembaban, intensitas cahaya serta kadar CO2 pada Thinger IO secara real-time. Pengujian dilakukan sebanyak 7x percobaan, pada pengujian suhu atau temperatur udara diperoleh nilai rata-rata error sebesar 0.32 %. Selanjutnya pada pengujian kelembaban udara diperoleh nilai rata-rata error sebesar 1.3 %. Selanjutnya pengujian kadar CO diperoleh nilai rata-rata sebesar 0.985 ppm, sedangkan data intensitas cahaya diperoleh rata-rata sebesar 199.75 lux.
ANALISIS KADAR VITAMIN D PADA PENERIMA VAKSIN SINOVAC SEBAGAI GAMBARAN SISTEM IMUNITAS
Authors: Yusmiati Siti Nur Husnul , Damayanti Aprilia Aly , Wijayanti Christina Destri Wiwis , Watoyani Tonny
Published: November 2023

The body's immune system is a system that detects a wide variety of outside biological influences, organisms will protect the body from infections, bacteria, viruses to parasites. During the current pandemic, the immune system is very important to prevent exposure to COVID-19. Efforts are made to be able to sufficient intake of vitamins and vaccinations. Vitamin D is one that is needed to prevent exposure to viruses. This study aims to determine vitamin D levels in sinovac vaccine recipients as an illustration of the immune system. This scientific paper research uses primary data analytic observation method with a cross-sectional design supported by literature studies, namely by describing the results of the research in the form of a percentage (%) decrease and increase in vitamin D compared to normal values. The results of the research on vitamin D levels receiving the Sinovac vaccine found that 92% or 23 patients out of 25 patients showed vitamin D levels were still within normal values and 8% or 2 patients showed vitamin D levels below normal values. It can be concluded that some of the research samples were in the normal range so that the immune system as the response of vitamin D to vaccines is still being seen. Keywords : SINOVAC Vaccine, Vitamin D, Immune System.
Single Parenting and Children’s Academic Performance in Primary Schools in Embu East Sub County, Kenya
Authors: Igandu Lucy Anne , Odek Antony , Marima Esther
Published: November 2023

Most single parents are ostracized by their communities, and this has profound impacts on their children’s academic performance. This study is based on the effect of single parenting on the children’s academic performance in primary schools in Embu East Sub County, Kenya. Specific objectives include: investigating the effect of a single parent’s income on the children’s academic performance; examining the effect of a single parent’s educational level on the children’s academic performance; and determining the effect of a single parent’s social support on the children’s academic performance in primary schools in Embu East Sub-County in Kenya. The study was guided by human development theory. The study applied a descriptive survey research design, and 388 respondents were selected using cluster and simple random sampling techniques. Furthermore, 34 key informants, mainly teachers, government officials, and local leaders, are also integrated into the study using purposive and convenient sampling in order to provide in-depth information. Descriptive data analysis was carried out in the form of frequencies and presented in frequency distribution tables, while inferential analysis was also done in the form of correlation and regression. The correlation analysis findings showed that income had a +0.853, education level had a +0.832, and social support had a +0.737 strong and statistically significant correlation with academic performance. Regression analysis also showed that all the social and economic factors had a positive effect on the academic performance of the children. It is recommended that the stakeholders focus on increasing income levels, encouraging educational prospects and accomplishments, and nurturing robust social support systems.
The Impact of Resource Utilization Practices on Inter-Ethnic Conflicts in Nakuru County, Kenya
Authors: Momanyi Zipporah Kerubo , Simiyu Ruth N. , Muchanga Kizito
Published: November 2023

Globally, conflicts arising from resource use are increasingly becoming common. This generated inter-ethnic violence that has caused death, strained relations among communities, led to loss of property, displacements, slowed economic growth, and increased sex-related crimes. Despite the government, local communities, and NGOs, among other institutions, putting effort into minimizing conflicts, they have yet to find a lasting solution. The overarching objective of the study was to evaluate the effects of resource-use practices on inter-ethnic conflicts in Nakuru County, Kenya. The study was conducted in Nakuru County and targeted household heads, government officials, civil society organizations, and community members. There were 246 respondents, taken as the sample size for the study. The study found that the major effects of conflicts were loss of life, displacement, loss of property, ethnic differences, and low income. The study concludes that the effects of resource-use practices on interethnic conflicts include loss of life, population displacement, discrimination, loss of property, and loss of market for goods, all of which have a significant impact on the economic status of the affected community. The research suggests that the consequences of resource-use practices on inter-ethnic disputes in the study area should be improved both at the national and county levels. This would make it possible for the people living in the area to advance economically.
REPERCUSSÕES DA PANDEMIA COVID-19 NOS INDICADORES DE ADOLESCENTES COM SOBREPESO E OBESIDADE
Authors: Ortellado Igor Ignacio de Souza , Geisler Sandonaid  Andrei , Oliveira Thaissy Fernanda de
Published: November 2023

Este estudo analisa o aumento da incidência de obesidade na adolescência durante a pandemia do COVID-19, com foco em sua relação com a saúde mental. Foram analisadas as causas subjacentes desse aumento, destacando o papel do sedentarismo, mudanças nos hábitos alimentares e o impacto psicológico da pandemia. Utilizando uma metodologia: de revisão integrativa da literatura, foi identificada uma correlação significativa entre o aumento da obesidade na adolescência e o risco do desenvolvimento de doenças psicologicas. Conclusão e os resultados esperados: enfatizam a importância de medidas de prevenção e intervenção para enfrentar esse desafio de saúde pública e fornecem uma base sólida para futuras pesquisas no campo da saúde em adolescentes.
A UTILIZAÇÃO DE PRINCÍPIOS PELO STF NO CONTEXTO DO ATIVISMO JUDICIAL E O EFEITO BACKLASH: LEITURAS DO ANTIPOSITIVISMO E DO REALISMO JURÍDICO
Authors: Fonseca Stephany Oliveira Giardini
Published: November 2023

Este artigo buscou discutir como a utilização dos princípios podem gerar o instituto conhecimento como ‘ativismo judicial’ e questionar as possíveis consequências das decisões pautadas em uma moral pré-definida pelo intérprete pode gerar insegurança jurídica e conflito com os demais poderes institucionais. O presente artigo também buscou entender o chamado efeito backlash.
UMA VISÃO PARTICULARISTA MORAL: A (IN)SUBSISTÊNCIA DO PRINCÍPIO DA SUPREMACIA DO INTERESSE PÚBLICO ANTE A LEI DA LIBERDADE ECONÔMICA
Authors: Ferreira Edmar Cézar Franco
Published: November 2023

O direito administrativo, desde os clássicos se funda em uma premissa de que o interesse público – conceito indeterminado – sempre prevaleceria sobre o interesse particular. Com advento de uma constituição eclética referido “princípio” não está sendo deveres contestado. Seu viés autoritário, aliada a incompatibilidade com o pluralismo dee idéias assegurado como fundamento da república (Art. 1º, Inc. V da Constituição) podem recomendar a sua superação, ou ao menos sua delimitação como razão de existência dos institutos do direito público, que não basta por si só, pois é necessária uma autorização legal específica e farta fundamentação para a limitação do interesse particular. De mais a mais, há que se considerar que referido preceito ignora que há intresse público na iniciativa particular, em especial quando protegidos pelo ordenamento jurídico. Nesse diapasão surge a Lei nº13.874/2019, auto denominada de Lei da Liberdade Econômica – LLE. Ora, como defender que em um ordenamento que tem liberdade como garantia (Art. 2º, Inc. I da LLE), que impõe que a intervenção da mão estatal seja excepcional e subsidiária (Art. 2º, Inc. III da LLE), que a regulação deve ser analisada previamente (Art. 5º da LLE) e que reconhece o ganho coletivo da iniciativa privada (Art. 49-A, parágrafo único do Código Civil) há um princípio que despreza o interesse privado de forma apriorística. No presente estudo, em uma visão particularista moral demonstraremos como que no mais tardar há que se ter um novo entendimento sobre o princípio do intresse público, o conformando com os ditames pluralistas da constituição.
Deep learning with a multi-task convolutional neural network to generate a national-scale 3D soil data product: Particle size distribution of the German agricultural soil-landscape
Authors: Ließ Mareike , Sakhaee Ali
Published: November 2023

Abstract. Many soil functions and processes are controlled by the soil particle size distribution. The generated three-dimensional continuous data product, which covers the particle size fractions of sand, silt, and clay in the agricultural soil-landscape of Germany, has a spatial resolution of 100 m and a depth resolution of 1 cm.  This product is an important component for predicting the effects of agricultural management practices and their adaptability to climate change, as well as for analyzing soil functions and numerous risks. The effectiveness of the convolutional neural network (CNN) algorithm in producing multidimensional, multivariate data products is demonstrated. Even though the potential of this deep learning approach to understand and model the complex soil-landscape relationship is virtually limitless, limitations are data-driven. Further research is needed to assess the required complexity and depth of the CNN and the inclusion of the landscape surrounding each soil profile.
Tecnologias open source para avaliação da eficiência energética em edificações
Authors: De Miranda Luz Samantha Ohana , Guillen Salas Juan Carlos , Gonçalves Pedro Henrique
Published: November 2023

As discussões sobre sustentabilidade como uma questão ambiental, social e econômica, aliada à revolução tecnológica vem mostrando um novo caminho para a prática projetual. Há crescente disponibilização de ferramentas de representação ou de avaliação da performance para auxiliar os profissionais na projetação. Sabe-se que a maioria dos projetistas fazem uso apenas das ferramentas de representação, como o AutoCAD, Revit e ArchiCad, deixando de lado as de simulação tão primordiais no auxílio às decisões, motivados pela ausência de conhecimento sobre a aplicabilidade e as vantagens dos softwares; pelo preconceito relacionado à dificuldade de manipulação; pela falta de legislações que regulamentem; e principalmente pelos elevados custos das licenças. Perante essa situação, as tecnologias open source para avaliação da eficiência energética em edificações se apresentam como uma alternativa de baixo custo ou gratuita. Nesse sentido, a hipótese guia da pesquisa foi que existem tecnologias open source gratuitas para avaliação da eficiência energética nas edificações. O objetivo da pesquisa foi identificar as principais ferramentas computacionais de código aberto gratuitas utilizadas para a simulação da eficiência energética de edificações. Assim, o processo metodológico consistiu na revisão da literatura especializada no tema. Em tal revisão foi encontrada uma lista de softwares disponíveis no mercado, mas apenas o EnergyPlus e o Grasshopper atenderam aos critérios de gratuidade e código aberto. O principal resultado da pesquisa foi que existem tecnologias open source gratuitas para avaliação da eficiência energética nas edificações.
O starym domu Czarnej Madonny. Do dziejów obrazu Matki Boskiej Częstochowskiej
Authors: Kotula Franciszek
Published: November 2023

Przedmiotem artykułu są dwa powiązane ze sobą zagadnienia. Jednym z nich to dzieje obrazu Matki Boskiej Częstochowskiej, drugim ścisły związek kulturowy, łączący południową Polskę z Morawami i ze Słowacją.
Rec.: J. Dowiat, Historia Kościoła katolickiego w Polsce (do połowy XV w.)
Authors: Ratusiński Bogusław
Published: November 2023

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Introducing Transformative Plant Biotechnology: Developing Synthetic Biology Tools for Plant Genetic Engineering and Safe Plant Biodesign
Authors: Yang Xiaohan
Published: November 2023

Plant biotechnology has been playing a more and more important role in plant genetic improvement for sustainable production of food, bioenergy and biomaterials. Synthetic biology holds great potential for transforming plant biotechnology research. Recently we developed multiple synthetic biology tools to facilitate plant transformation, multigene stacking, genome editing, and safe biosystems design. Specifically, we adopted a UV-visible green fluorescent protein (GFP) marker for early in vivo screening of transgenic events and real-time tracking of transgenic plants. In general, complex plant traits are controlled by multiple genes. The ability to stack multiple genes in plants is of great importance in the development of crops with desirable traits but can be challenging due to limited selectable marker options. To address this limitation, we developed a split selectable marker system based on protein splicing elements called “inteins” for Agrobacterium-mediated co-transformation in plants. To facilitate the delivery of gene editing agents into plant cells, we created an intein-mediated split-Cas9 system. To expedite multiplexed CRISPR/Cas-based genome editing, we developed a new platform, called “PARA”, for the rapid assembly of gRNA arrays. For safe plant biodesign, we created plant-based biosensors for detecting CRISPR-mediated genome engineering. Also, we demonstrated that anti-CRISPR proteins were very efficient for inhibiting CRISPR/Cas9-based tools in multiple plant species, laying a foundation for the future application of anti-CRISPR proteins in tunable genome editing in plants.