bluuebunny/crossref_metadata_2025 huggingface dataset:
Differential expression of heparan sulfate 6-O-sulfotransferase 1 in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding heparan sulfate 6-O-sulfotransferase 1, HS6ST1, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. HS6ST1 was also differentially expressed in the tumor cells of patients with triple negative breast cancer. HS6ST1 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of HS6ST1 in primary tumors of the breast was correlated with overall survival in patients with luminal B and HER2+ subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. HS6ST1 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Analisis Model Bisnis Industri Permata
Authors: Saputra Adhimas Ito Delly
Published: July 2022

Analisa model bisnis industri berlian
Kajian Model Bisnis pada Industri Kapal Pesiar
Authors: Sekininno Justin Jordan
Published: July 2022

Industri bisnis kapal pesiar Cruise ship seperti America's Cruise Line pernah mengalami masakenaikan (rise). Namun seiring berjalannya waktu, bisnis industri kapal ini mengalamipenurunan (fall). Studi ini bertujuan untuk mengetahui alasan penurunan (fall) dan kenaikan(rise) pada bisnis kapal pesiar. Studi ini menggunakan studi kasus jamak pada bisnis kapal pesiaryang bergerak di bidang jasa dengan analisis business model canvas, business pattern, businessenvironment & value proposition canvas. Bisnis kapal pesiar pernah tren pertumbuhan dansukses karena memiliki value proposition memberikan layanan jelajah terbaik kepadapenumpangnya di seluruh dunia. Namun, bisnis kapal pesiar mengalami penurunan karena keyactivities terkena dampak dari pandemic COVID-19. Studi merekomendasikan key activities danvalue proposition menawarkan fasilitas rekreasi terbaik untuk memenuhi kebutuhan pelanggan
Studi Pertanian Berkelanjutan pada Aspek Praktik, Topik dan Manfaat
Authors: Umam Muhammad Hafiz
Published: July 2022

Pertanian berkelanjutan adalah suatu sistem terpadu praktik produksi tanaman dan hewan yang memiliki penerapan spesifik lokasi dalam jangka panjang yang memiliki kriteria, praktik dan manfaat.
Differential expression of CDP-diacylglycerol synthase 1 in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding CDP-diacylglycerol synthase 1, CDS1, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. CDS1 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of CDS1 in primary tumors of the breast was correlated with distant metastasis-free survival in patients with luminal B subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. CDS1 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Analisis Model Bisnis Retail Video Blockbuster
Authors: Abidin Amanda Namira
Published: July 2022

Bisnis retail persewaan film dan video game Blockbuster pernah mengalami masa kenaikan (rise). Namun sejak tahun 2000, bisnis hiburan ini mengalami penurunan (fall). Studi ini bertujuan untuk mengetahui alasan penurunan (fall) dan atau kenaikan (rise) pada bisnisBlockbuster. Studi ini menggunakan studi kasus tunggal pada bisnis Blockbuster yang bergerak di bidang retail video dengan analisis business model canvas, business pattern, business environment & value proposition canvas. Bisnis ini pernah tren pertumbuhan dan sukses karena memiliki value proposition penyewaan yang fleksibel. Namun, bisnis Blockbuster mengalami penurunan karena key activities terlalu berfokus pada toko DVD fisik. Studi merekomendasikan key activities film dan game yang disediakan di update secara teratur sehingga customer bisa mendapatkan versi terbaru segera setelah dirilis.Kata Kunci: Blockbuster, business model canvas, model bisnis, retail video, value proposition canva
Hà Nội đầu tư cho phát triển giáo dục và đào tạo giai đoạn 2019 - 2025
Authors: TKLV QLKT
Published: July 2022

Hà Nội đầu tư cho phát triển giáo dục và đào tạo giai đoạn 2019 - 2025
Kesuksesan dan Kejatuhan Model Bisnis Elektronik Apple: Studi Kasus pada iPod
Authors: Novitry Ellysyah
Published: July 2022

Dengan beberapa produk Apple yang tersedia iPod merupakan produk pertamaApple yang sangat sukses hingga produk dan brand ini sangat terkenal dan disukai oleh banyak orang. Apple iPod awalnya dirilis pada tahun 2001 sebagai pemutar MP3 yang memungkinkan Anda membawa "1.000 lagu di saku Anda" dan sejak itu berkembang menjadi pusat media pribadi dengan banyak fitur. Pada 2011, empat model iPod tersedia: iPod classic, iPod touch, iPod nano dan iPod shuffle. Semua model iPod, kecuali Shuffle, sekarang memutar video di atas musik dan iPod touch bahkan menampilkan aplikasi seluler seperti iPhone. IPod memiliki banyak kegunaan, termasuk stereo pribadi atau disk jockey, pemutar video dan media center portabel.
Bài tập Triệu Quang Sơn-TKLV
Authors: TKLV QLKT
Published: July 2022

Việc gần 10.000 cán bộ, nhân viên y tế bỏ việc thời gian qua, trong bối cảnh "dịch chồng dịch" đang rình rập ở nhiều tỉnh như dịch sốt xuất huyết, dịch cúm A… điều này tác động rất lớn đến chất lượng khám, chữa bệnh của các bệnh viện.
What is the impact of COVID-19 pandemic, season and temperature on prevalence of childhood diarrhoeal cases and treatment in India during 2018-2021– A 41 months cross-sectional research study?
Authors: Kumar Dr Piyush
Published: July 2022

Abstract - Globally diarrheal illness is the second leading reason behind death in kids underneath 5 years accounting for 525 000 kids death annually, which can be treated and prevented if timely interventions are applied as well as can be prevented through safe drinking-water with adequate sanitation and hygiene. Global prevalence of childhood diarrhoea is about 1.7 billion cases per annum. SARS-CoV utilize the Angiotensin-converting enzyme 2 (ACE2) with the serine protease TMPRSS2 for S protein priming. ACE2 and TMPRSS2 are expressed in lung, as well as small intestinal epithelia, added to this the ACE2 is expressed in the oesophagus, liver, and colon; SARS-CoV-2 binds strongly with ACE2 (10–20 times) compared with other SARS-CoV. The purpose of this research is to examine the epidemiology of childhood diarrheal events during COVID-19-period and comparing it with the pre-pandemic period of 2018-2019 as well as monthly-seasonal-temperature variations during different months of pre-pandemic and pandemic period associated diarrhoea to identify any changes in the usual seasonal pattern of childhood diarrheal events. A total of 11171113 eligible childhood diarrhoea (0-5 years) and 1704819 Childhood diarrhoea treated in Inpatients (0-5 years) were analyzed during the 41 month study period. A total of 11171113 (mean-272466.2; [95% Conf. Interval means] 250375.4- 294556.9) childhood diarrhoea (mean-; [95% Conf. Interval means]) (0-5 years), 1704819 (mean 41580.95-; [95% Conf. Interval means - 36458.75- 46703.15]) childhood diarrhoea treated in Inpatients (0-5 years), 7603860 (mean 185460-; [95% Conf. Interval means - 159578.8- 211341.2]) were included in this study on an all-India basis. The 41 months of study when grouped into two groups as pre-pandemic era and pandemic era shows that the Monthly /seasonally Prevalence of Childhood diarrhoea (0-5 years) were MAX in July 2019 monsoon season during pre-pandemic period with 418722 cases ([95% CONF. INTERVAL] 299758.7- 338763.3; STD. ERR.- 9427.519; MEAN-319261; STD. DEV- 46185.22; and MIN-261319 in December 2019, post monsoon season, See table- 1, 3, and 4; figure-5 and 6. During the COVID-19 pandemic period Monthly /seasonally Prevalence of Childhood diarrhoea (0-5 years) were MAX in February 2020 winter season during pre-pandemic period with 284075 cases ([95% CONF. INTERVAL] 188170.3 - 224635.3; STD. ERR.- 8600.616; MEAN-206402.8; STD. DEV- 35461.25; and MIN-158007 in April 2020.KEYWORDS: - Seasonal variation, Diarrhoea, COVID-19, India, Prevalence, temperature variation,
Analisis Model Bisnis Retail Permainan Video Game Stop
Authors: Carazein Angeline Shakila
Published: July 2022

Bisnis GameStop yang didirikan pada tahun 1984 mengalami masa kenaikan (rise). Namun sejak tahun 2016, industri video game digital ini mengalami tren penurunan (fall). Studi ini bertujuan untuk mengetahui alasan penurunan (fall) dan kenaikan (rise) pada bisnis GameStop. Studi ini menggunakan studi kasus jamak pada bisnis GameStop yang bergerak di bidang video game digital dengan analisis business model canvas, business pattern, business environment & value proposition canvas. Bisnis GameStop pernah tren pertumbuhan dan sukses karena memiliki memiliki jaringan distribusi yang luas serta terdapat sekitar 4000 toko ritel di seluruh dunia. Namun, bisnis Gamestop mengalami penurunan karena perubahan pasar yang menyebabkan performa penjualan GameStop menurun belasan hingga puluhan persen. Studi merekomendasikan menambah beberapabahasa dari berbagai negara untuk memudahkan para customer dalam bertransaksi di GameStop.
Differential expression of agrin in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding agrin, AGRN, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. AGRN was also differentially expressed in the tumor cells of patients with triple negative breast cancer. AGRN mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of AGRN in primary tumors of the breast was correlated with overall survival in human breast cancer. AGRN may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of KIAA1522 in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding KIAA1522, KIAA1522, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. KIAA1522 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of KIAA1522 in primary tumors of the breast was correlated with overall survival in patients with luminal A and normal subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. KIAA1522 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of SIX homeobox 4 in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding SIX homeobox 4, SIX4, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. SIX4 was also differentially expressed in the tumor cells of patients with triple negative breast cancer. SIX4 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of SIX4 in primary tumors of the breast was correlated with recurrence-free survival in patients with luminal A and luminal B subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. SIX4 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Do Statistical Rules Interfere with Political Beliefs?
Authors: Ghasemi Omid , Roberts Andrew , Handley Simon
Published: July 2022

Recent studies have shown that individuals heavily rely on their own political attitudes and thus underweight appropriate evidence or normative rules. Such an effect of prior beliefs on reasoning is assumed as evidence of ideological blindness and reasoning impairment. Across 3 preregistered experiments (N = 1030), we examined whether individuals are truly insensitive to evidence inconsistent with their political views. Participants, including climate believers and deniers (Experiments 1 and 2), and pro- and anti-vaxxers (Experiment 3), were presented with a series of base-rate arguments with neutral, climate, or COVID-19 vaccine contents and were asked to evaluate them either based on their beliefs or statistical rules. The results showed that climate deniers and anti-vaxxers were not impacted by their political beliefs in their reasoning as the conflict between statistical rules (i.e., base-rates) and diagnostic information did not interfere with their statistical judgments. More importantly, regardless of an argument’s content, such a conflict interfered with belief-based judgments. These findings contradict the notion that ideology impairs reasoning and suggest that individuals’ judgments are less impacted by background beliefs than has been assumed previously, and more importantly, reasoners are still sensitive to normative rules that disagree with their beliefs, even on ideological topics.
Tiêu thụ năng lượng bền vững nhằm thúc đẩy tăng trưởng kinh tế phục vụ chiến lược tăng trưởng xanh giai đoạn 2021 - 2030
Authors: Công Phạm Thành
Published: July 2022

Tiêu thụ năng lượng và tăng trưởng kinh tế có mối quan hệ chặt chẽ không thể tách rời, nó ảnh hưởng đến tình hình phát triển về mọi mặt của quốc gia. Việc điều phối tốt mối quan hệ giữa tiêu thụ năng lượng và tăng trưởng kinh tế sẽ giúp cho nền kinh tế phát triển mạnh mẽ, trên cơ sở năng lượng được sử dụng một cách tối ưu, tránh tình trạng tiêu thụ năng lượng quá mức, dẫn tới cạn kiệt năng lượng, nhưng tình hình kinh tế vẫn không phát triển hoặc phát triển chậm. Một số nghiên cứu đã điều tra mối các mối quan hệ giữa tiêu thụ năng lượng và tăng trưởng kinh tế bởi vì năng lượng là bánh xe của tăng trưởng kinh tế. Nó là một yếu tố sản xuất quan trọng cùng với vốn và lao động. Năng lượng được coi như là một yêu cầu quan trọng cho tăng trưởng kinh tế và là một yếu tố tiềm năng ngăn chặn sự phát triển kinh tế và xã hội nếu kiểm soát không tốt
Analisis Rise and Fall pada Perusahaan Pakaian Victoria's Secret
Authors: Azzahri Ellina Fahra
Published: July 2022

Bisnis pakaian dalam Victoria’s Secret pernah mengalami masa kenaikan (rise). Namun sejaktahun 2015, industri pakaian ini mengalami tren penurunan (fall). Studi ini bertujuan untukmengetahui alasan penurunan (fall) dan kenaikan (rise) pada bisnis pakaian dalam victoria’ssecret. Studi ini menggunakan studi kasus tunggal pada bisnis victoria’s secret yang bergerak dibidang fashion dengan analisis business model canvas, business pattern, business environment& value proposition canvas. Bisnis pakaian dalam, baju tidur, olahraga dan body care ini pernahtren pertumbuhan dan sukses karena memiliki value proposition desain yang lebih up-to-datedaripada brand lain. Namun, bisnis pakaian ini mengalami penurunan karena value propositionfashion show yang ditayangkan kurang diterima oleh masyarakat karena kurang mengikuti tren.Studi merekomendasikan customer relationship melakukan marketing dengan meningkatkankualitas fashion show yang diadakan.
Pariwisara Pasar Terapung Sebagai Upaya Meningkatkan Keterampilan Sosial Mahasiswa_Ellena Ellena
Authors: ELLENA ELLENA
Published: July 2022

Social skills can be acquired through the learning process of family, peers, college and student surroundings. Social skills are indispensable in any student's social life because it is a capital for individual differences, a basis for living with others, working together, controlling yourself, reasoning, working on conflict resolution, and students are able to deal with life's problems and have confidence. (Bahfen, M. 2020). The purpose of this study is to understand how floating market tourism is in an effort to improve student social skills. The writing USES a type of qualitative research using descriptive methods, using data collection techniques of observation and documentation in which writers use literature studies based on articles, books, and journals. It is hoped to be useful for all in the world, which can give a cognitive picture of the importance of having social skills primarily in order to interact with peers to communicate, and in cooperation with floating market tourism. Keywords: Tourism, A Floating Market, Social Skills
Quantum Mechanics and General Relativity are fully compatible, and have a common origin: the expanding (hyper) balloon universe
Authors: Waugh Subhajit
Published: July 2022

NOTE: For a brief summary with less technical details (for general, non-scientific readers) here is a link: https://doi.org/10.5281/zenodo.7343171 (All are requested to read that first).Quantum Mechanics and General Relativity appears to be incompatible because we are using the wrong model of the universe. Nature does not use two separate rule-books, but uses two different viewpoints. To see how the conflicting demands of Quantum Mechanics and General Relativity can be easily satisfied, we need the true model of our universe.Ever since Hubble’s law was discovered, scientists speculated that the analogy of an expanding balloon best described the shape of our universe. This view was rejected based on wrong assumptions and replaced by the presently accepted model of a flat and infinite universe, which is wrong! We are confident that we have measured the universe to be (3d) flat using two different methods. Unfortunately, neither method is capable of measuring the extrinsic curvature of a 3d hyper-surface.
Tiểu sử Ernst Boris Chain
Authors: Lai Thuong
Published: July 2022

Sir Ernst Boris Chain (19.6.1906 – 12.8.1979) là một nhà hóa sinh người Anh gốc Do Thái và Đức, đã đoạt giải Nobel Sinh lý và Y khoa năm 1945 cho công trình nghiên cứu về penicillin.
Thiết kế luận văn
Authors: TKLV QLKT
Published: July 2022

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Aktivitas Harian Burung Kakatua Jambul Kuning (Cacatua galerita) di Bontomarannu Education Park
Authors: Ali Nurjamilah Zakiyah
Published: July 2022

Aktivitas adalah serangkaian tindakan yang dibuat oleh individu dan organisme terhadap dirinya sendiri atau lingkungannya, yang mencakup sistem atau organisme lain di sekitarnya serta lingkungan fisik (mati). Pengamatan tentang aktivitas harian burung kakatua jambul kuning (Cacatua galerita) belum banyak dilakukan sehingga dilakukanlah sebuah penelitian yang bertujuan untuk mengetahui aktivitas harian apa saja yang dilakukan oleh burung kakatua (Cacatua galerita) setiap harinya. Hasil penelitian menunjukkan bahwa perilaku yang dominan dilakukan yaitu makan, sosial, vokalisasi, bertengger, memanjat, berpindah tempat dan menaikkan jambulnya serta dari hasil wawancara selain dari perilaku tersebut kakatua jambul kuning juga melakukan kegiatan mebersihkan dirinya dan perilaku kawin.
SEJARAH PERKEMBANGAN PEMERINTAH
Authors: ILHAM MUHAMMAD
Published: July 2022

Penelitian ini ingin mengetahui penggunaan metode Transect sebagai metodeperencanaan partisipatif dalam penggalian potensi dan permasalahan secaravisual serta praktek pada perencanaan pembangunan partisipatif di DesaTonrong Rijang Kabupaten Sidenreng Rappang. Dengan mengetahui tujuantersebut maka akan memberikan masukan metode yaitu Transect agar dapatdigunakan sebagai metode perencanaan pembangunan partisipatif dan dapatmenambah pemahaman dan pengetahuan yang luas bagi para peneliti tentangmetode perencanaan pembangunan partisipatif pada perencanaanpembangunan. Metode yang digunakan adalah dengan melakukan observasi, wawancara mendalam serta melakukan studi kepustakaan yang berkaitandengan penelitian. Teknik yang digunakan dalam menganalisi penelitian iniadalah Analisis Data Model Interaktif. Teknik tersebut melakukan pengolahandalam analisis data kualitatif secara interaktif dan hal ini berlangsung terusmenerus sampai selesai, sehingga datanya jenuh. Aktivitas olahan analisisdatanya, yaitu Mengumpulkan Data, Mereduksi Data, Menyajikan Data, danPengambilan Kesimpulan. Hasil penelitian menunjukkan bahwa Transectmerupakan hal yang baru dan tidak dikenal oleh masyarakat desa dalam sebuahperencanaan pembangunan. Proses interaksi sosial masyarakat terjadi dalamperencanaan pembangunan serupa dengan transect, seperti saat melakukanpendampingan kepada „pihak luar‟ dalam kegiatan tertentu, tetapi kegiatandominan hanya dalam bentuk musyawarah mufakat seperti yang telah lazim danturun temurun dilakukan.(Mustanir & Yasin, 2018)
Rheinische Friedrich-Wilhelms-Universität Bonn 8366675858: A New Theory of Serendipity (2022)
Authors: Lai Thuong
Published: July 2022

Rheinische Friedrich-Wilhelms-Universität Bonn 8366675858 Holding: A New Theory of Serendipity: Nature, Emergence and Mechanism (Yr. 2022). Pbk.
Differential expression of lysine demethylase 4B (KDM4B) in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding lysine demethylase 4B, KDM4B, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. KDM4B mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of KDM4B in primary tumors of the breast was correlated with overall survival in patients with basal and luminal A subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. KDM4B may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of STIL in cancers of the breast.
Authors: Mamoor Shahan
Published: July 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding SCL/TAL1 interrupting locus, STIL, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. STIL mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of STIL in primary tumors of the breast was correlated with overall survival in patients with luminal B subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. STIL may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Naik Turunnya Bisnis Vaksinasi dalam Perspektif Model Bisnis
Authors: Valois Pierrezeus Reinard
Published: July 2022

Bisnis vaksinasi pada masa pandemic mengalami kenaikan (rise). Namun, industri kesehatan ini sangat berisiko ketika customer tidak percaya dan menyebabkan penurunan (fall). Studi ini bertujuan untuk mengetahui alasan penurunan (fall) dan kenaikan (rise) pada bisnis vaksinasi. Studi ini menggunakan studi kasus jamak pada bisnis vaksinasi yang bergerak di bidang kesehatan dengan analisis business model canvas, business pattern, business environment & value proposition canvas. Bisnis vaksinasi menjadi tren pertumbuhan dan sukses karena dibutuhkan oleh banyak orang. Namun, bisnis vaksinasi mengalami penurunan ketika semua orang sudah menerima vaksin yang diperlukan dan tidak ada wabah penyakit yang sedang beredar pada saat itu.
Characteristics and Predictors of Scientific Practices: A Large-scale Study
Authors: Büssing Alexander Georg , Dietz Christian , Grahmann Marc , Klein Hans-Peter , Möller Andrea
Published: July 2022

While scientific practices are internationally considered as an integral part of science instruction to achieve scientific literacy, only scarce knowledge exists about their common implementation in everyday science lessons. In contrast to prior studies, which used either only a small selection of lessons or relied on self-reported data from teachers, our study builds on a large-scale observational study to investigate the frequency, duration, and social settings of experiments, microscopy, the use of models, and dissection in biology education. As part of their professional development, biology pre-service teachers observed 2556 biology lessons, of which only 762 lessons (29.8%) included at least one scientific practice. Inspecting the duration of the specific methods allowed for a more pronounced view, showing that for example experiments were only conducted in 2:18 minutes in a hypothetical 45-minute lesson. These Experiments (n = 308) were mainly applied in group settings (39%), microscopy (n = 86) most often in partner settings (67.8%), and modelling (n = 418) occurred mainly in teacher-centered settings (68.4%). Using regression analyses we found variables such as school track, grade level, class size, and room conditions to be significant predictors, highlighting relevant variables that may hinder biology teachers from implementing scientific practices into their lessons. Overall, with the results of this large-scale observation study we add relevant knowledge about scientific practices, which can be used for supporting the implementation of more scientific practices through teacher training, learning materials, and school development, respectively.
UCI - A New Theory of Serendipity
Authors: Lai Thuong
Published: July 2022

UC Irvine - A New Theory of Serendipity: Nature, Emergence and Mechanism (June 27, 2022).
Perkembangan Ilmu Pemerintahan dan Penerapan Good Governance pada Pemerintahan Daerah
Authors: Khaerunnisa Mutia
Published: July 2022

Sampai saat ini ilmu pemerintahan masih menjadi sebuah diskursus yang hangat dan perdebatan yang seru baik diantara internal ilmuwan dan praktisi pemerintahan maupun kalangan eksternal dalam bidang keilmuan lainnya. Dikatakan demikian karena masih menjadi tanda tanya besar sebagian kalangan mengenai apakah ilmu pemerintahan itu sudah mandiri dan otonom ataukah dia merupakan cabang dari ilmu lainnya seperti ilmu politik dan ilmu administrasi. Pertanyaan ini merupakan bentuk rasa ingin tahu secara mendalam mengenai posisi ilmu pemerintahan yang harus dijelaskan oleh para pemerhati ilmu pemerintahan (ilmuwan pemerintahan). Dalam banyak hal ditemukan penjelasan yang beragam dari beberapa ahli dan literatur tetapi masih belum memberikan kesatuan pemahaman secara utuh mengenai ilmu pemerintahan tersebut. Terutama mengenai obyek pengkajian ilmu pemerintahan (obyek materi dan obyek forma), kemudian metode yang digunakan dalam mengkaji serta pokok bahasannya apa saja. Akibatnya ilmu pemerintahan belum diterima secara utuh sebagai ilmu yang mandiri dan otonom. Ada- pun lebih banyak dijumpai penelusuran dan pengkajian pada tataran praktik penyelenggaraan pemer- intahan tetapi belum menyentuh pada khasanah pengembangan ilmu itu sendiri yang melahirkan teori pemerintahan. Untuk itu perlu dirumuskan ketiga hal diatas dalam rangka mengenal ilmu pemerintahan sebagai ilmu yang mandiri dan otonom.
UC San Diego Holding DOI: 10.2478/9788366675865-007
Authors: Cranier Louis
Published: July 2022

UC San Diego Holding DOI: 10.2478/9788366675865-007Identifier: EISBN: 8366675866
Immediate Cross Language Transfer of Novel Articulatory Plans for Speech in Bilinguals
Authors: Shiller Douglas M , Bobbitt Sarah , Lametti Daniel Robert
Published: July 2022

Current models of second language (L2) acquisition focus on interactions with a first language (L1) at the level of speech sound targets. In multilinguals, the degree of interaction between the articulatory plans that guide speech in each language remains unclear. Here, we directly address this question in bilingual speakers. We use a sensorimotor adaptation paradigm to drive the acquisition of novel articulatory plans for speech in one language and then measure the extent to which these new motor plans influence articulatory plans in the speaker's other language. Twenty L1-French, L2-English bilinguals adapted their speech production to a real-time alteration of vowel sounds. In one session, the adaptation was acquired during French sentence production; in a second session, the adaptation was acquired during English sentence production. In each session, cross-language transfer of these novel articulatory plans for speech was assessed using a transfer task that involved the production of French and English words with heavily noise-masked auditory feedback. Sensorimotor adaptation that countered the vowel sound alteration was observed in both French and English. Regardless of the linguistic context in which the adaptation was acquired, the adaptation transferred to the production of words in both languages. The amount of transfer did not depend on whether the adaptation was acquired in the participant's L1 or L2. In a second experiment, the result was replicated with twenty L1-English, L2-French speakers. The experiments support the idea that, in bilinguals, the interaction between L1 and L2 articulatory motor plans is rapid and bidirectional.
Three simple Lemurrian breathing techniques to heal all types of mental disorders
Authors: Kalimuthu Sennimalai
Published: July 2022

The mental disorders such as Neurodevelopmental Disorders, Intellectual Development Disorder, Global Developmental Delay , Communication Disorders , Autism Spectrum Disorder , Attention-Deficit Hyperactivity Disorder (ADHD), Bipolar and Related Disorders, Mania, Depressive Episodes, Anxiety Disorders, Generalized Anxiety Disorder (GAD), Social Anxiety Disorder , Specific Phobias , Panic Disorder, Separation Anxiety Disorder, Trauma- and Stressor-Related Disorders, Acute Stress Disorder, Adjustment Disorders, Post-Traumatic Stress Disorder (PTSD), Reactive Attachment Disorder, Dissociative Disorders, Dissociative Amnesia, Dissociative Identity Disorder, Somatic Symptom Disorders, somatic Symptom Disorder, Illness Anxiety Disorder, Conversion Disorder, Factitious Disorder, Feeding and Eating Disorders, Anorexia Nervosa, Rumination Disorder, Pica, Binge Eating Disorder, Sleep-Wake Disorders, Narcolepsy, Insomnia Disorder, Breathing-Related Sleep Disorders, Parasomnias, Restless Legs Syndrome, Disruptive, Impulse Control and Conduct Disorders, kleptomania, Pyromania, Intermittent Explosive Disorder, Conduct Disorder, oppositional Defiant Disorder, Depressive Disorders, Disruptive mood dysregulation disorder:, Major depressive disorder, Other specified depressive disorder, Substance/medication-induced depressive disorder, Depressive disorder due to another medical condition can be easily cured by simple Lemurrian breathing techniques.
The Ising model as a discovery tool in cognitive sciences
Authors: Kozhin Foma
Published: July 2022

In this contribution we will explore how the Ising model can connect different physical phenomena with the cognitive sciences.
Assessing Alexithymia in Adolescents: Psychometric Properties of the Perth Alexithymia Questionnaire in High School Students
Authors: Trimble Annette , Robinson Ken , Preece David
Published: July 2022

Conceptually, alexithymia is a key transdiagnostic risk factor for the development of numerous psychopathologies across the lifespan. However, to date, most alexithymia research has focused on adults, with adolescent work limited by a lack of validated age-appropriate assessment tools. Recently, the Perth Alexithymia Questionnaire (PAQ) was introduced to enhance the comprehensiveness of alexithymia assessments, but its psychometric properties have only been tested in adults. In this study, we address this by examining the psychometric properties of the PAQ in a sample of English-speaking high school students (N=225, aged 11 to 18), and use the PAQ to further establish the structure of the alexithymia construct in adolescents. Confirmatory factor analysis revealed that all PAQ items conformed well to the expected factor structure, supporting that the PAQ was measuring a coherent multidimensional construct, consistent with the attention-appraisal model of alexithymia. All subscale and composite scores had good to excellent internal consistency (αrange = .83 to .95) and correlated in expected ways with other emotion measures. Together, these findings suggest that the multidimensional structure of the alexithymia construct manifests similarly in adolescents and adults, and that the PAQ is a valid and reliable measure of alexithymia in adolescents.
The evolution of gender dimorphism in the human voice: The role of octave equivalence
Authors: Bannan Nicholas , Dunbar R. I. M. , Bamford Joshua Silberstein
Published: July 2022

Humans exhibit what appears to be a unique vocal property: octave equivalence whereby adult male voices are, on average, an octave lower in pitch than those of adult females and children. The evolutionary significance of this seems largely to have escaped notice. While sexual selection might explain why male voices are generally lower, it cannot explain why they should be so much lower than what would be expected for body size, nor why the average difference should be exactly one octave. Nor does a generalised dimorphism convey why precisely tuned octaves feature so commonly in human vocal interaction. The octave features strongly in the organisation of music. A consequence of this characteristic of human pitch perception and production is the capacity to share and respond to vocal pitches (and their instrumental equivalents) as if they are ‘the same’ irrespective of the difference in range, a phenomenon known as octave equivalence. We investigate the nature of octave equivalence from an adaptive perspective and propose a hypothesis for its evolution based on the importance of chorusing for social bonding and pitch-matching in inter-generational exchange.
Evaluating a Telehealth Single-Session Consultation Service for Clients on Psychotherapy Wait-Lists
Authors: Sung Jenna , Bugatti Matteo , Vivian Dina , Schleider Jessica L.
Published: July 2022

Outpatient mental health clinics across the country are struggling to meet acute demand for mental health services, resulting in months-long waitlists for people seeking care. Providing evidence-based, single session interventions to treatment-seeking individuals while they are waiting for treatment may help address this crisis. One such intervention, the Single-Session Consultation (SSC), was found to be an effective, acceptable, and feasible low-intensity treatment option when delivered in person. The current study evaluates the telehealth delivered SSC during the COVID-19 pandemic to individuals waiting to access mental health care. Of the 147 people offered an SSC, 95 (64.63%) accepted the invitation, 74 (77.89%) scheduled with a clinician, and 65 (87.84%) attended the session, surpassing feasibility benchmarks. Participants saw pre-to-post intervention improvements in hopelessness (dz = .91, p < .001) and readiness for change (dz = -0.49, p < .001). At 2-weeks follow-up, anxiety symptoms reduced significantly (dz = .40, p = .04) but depression symptoms did not decrease significantly (dz = .21). Participants rated telehealth-SSC sessions as highly acceptable and developed a close therapeutic alliance (M = 6.13, SD = 0.76). The telehealth-SSC was acceptable, feasible, and effective in the short-term, suggesting its utility as a low-intensity, scalable interventions for people on waiting lists for outpatient mental health care.
Norms and the evolution of leaders’ followership
Authors: Cabrales Antonio , Hauk Esther
Published: July 2022

In this paper we model the interaction between leaders, their followers and crowd followers in a coordination game with local interaction. The steady states of a dynamic best-response process can feature a coexistence of Pareto dominant and risk dominant actions in the population. The existence of leaders and their followers, plus the local interaction, which leads to clustering, is crucial for the survival of the Pareto dominant actions. The evolution of leader and crowd followership shows that leader followership can also be locally stable around Pareto dominant leaders. The paper answers the questions (i) which Leader should be removed and (ii) how to optimally place leaders in the network to enhance payoff dominant play.
The Inequality of Lifetime Pensions
Authors: Shi Jiaxin , Kolk Martin
Published: July 2022

Research on social stratification has mostly focused on working-age populations. With rapidly aging populations increasing across the rich world, inequalities at older ages are an increasingly relevant part of how contemporary societies are stratified. Here, we highlight an aspect of inequality that has been largely unexamined—the inequality of lifetime accumulated pensions. In contrast to most previous research on old-age inequality comparing social groups, we focused on total-population-level inequality. Using Swedish register data covering the retired population born from 1918–1939, we found that lifetime pensions are much more unequal than pre-retirement earnings and yearly pensions. Our findings also show that the demographic driver—mortality—is the most important factor explaining the inequality of lifetime pensions within cohorts as well as its changes across cohorts. Pension policies can affect lifetime pension inequality, but such effects are limited in magnitude unless they directly affect the number of years of receiving pensions.
Meningkatkan Kemampuan Interaksi Sosial Peserta Didik Melalui Karya Wisata Pasar Terapung Lok Baintan
Authors: Santi Karunia
Published: July 2022

Peran penting adanya pendidikan adalah mempersiapkan warga negara yang dapat berkembang secara terintegrasi perilaku demokratis, baik dalam tatanan individu maupun sosial yang meningkatkan kehidupan sosial demokrasi yang produktif. Oleh sebab itu, proses pembelajaran haruslah sebagai sarana untuk mempersiapkan peserta didik agar dapat berinteraksi secara luas dengan masyarakat, mengembangkan sikap dan perilaku demokratis, serta mendorong produktivitas kegiatan belajar peserta didik. Hal ini dapat diterapkan dengan menerapkan bimbingan kelompok yang dapat dilakukan untuk meningkatkan interaksi siswa yaitu satu diantaranya adalah program karya wisata, sehingga peserta didik dapat berinteraksi dengan baik dan dapat meningkatkan keterampilan sosialnya di dalam masyarakat sebagaimana yang di harapkan oleh hukum nasional dan tujuan pendidikan. Sementara itu, pengembangan diri sangatlah diperlukan dalam aktualisasi individu dalam lingkungan sekitar peserta didik. Model pembelajaran dengan bimbingan kelompok ini memberikan solusi untuk mengoptimalkan keterampilan sosial dalam menanggapi kesenjangan sosial dan sosial sikap perilaku peserta didik serta gejala dan masalah sosial dalam masyarakat hari ini. Masalah inti yang diangkat dalam penulisan artikel ini yaitu bagaimana meningkatkan kemampuan berinteraksi, komunikasi dan hubungan sosial antar peserta didik melalui karya wisata Pasar Terapung Lok Baintan. Penulisan artikel ini bertujuan untuk mengetahui bagaimana meningkatkan kemampuan berinteraksi, komunikasi dan hubungan sosial antar peserta didik melalui karya wisata. Metode penelitian ini adalah penelitian kualitatif dengan cara mendeskripsikan variabel penelitian secara kualitatif, penelitian ini akan mengkaji variabel berdasarkan kajian literasi (Library research). Hasil penelitian menyimpulkan bagaimana model interaksi sosial yang dapat dilakukan untuk meningkatkan kemampuan berinteraksi, komunikasi dan hubungan sosial antar peserta didik melalui karya wisata.
नेपालमा आर्थिक विकास: वित्तीय प्रणालीको असल अभ्यास र दिगो विकास
Authors: टण्डन Tandan सुरोज Suroj
Published: July 2022

आर्थिक विकासको लागि वित्तीय प्रणालीमार्फत पुँजी, सिप, अनुभव, ज्ञान र प्रविधिलाई समुचित उपयोग गरी सहरदेखि गाउँसम्म आर्थिक क्रियाकलाप बढाउन, पिछडिएको क्षेत्र तथा वर्गको व्यावसायिकता अभिवृद्धि गर्न, कर्जासँगै ज्ञान, पुँजीसँगै सिप, प्रविधिसँगै अनुभव प्रदान गरी साना, मझौला तथा ठुला व्यवसायलाई सहयोग गर्न आवश्यक छ। उत्पादनशील क्षेत्रमा आन्तरिक तथा बाह्य लगानीको अपर्याप्तता, अनुत्पादक क्षेत्रमा केन्द्रित लगानी, न्यून पुँजीगत खर्च, उच्च उत्पादन लागत, आर्थिक वृद्धि र रोजगारी सिर्जनाबिचको कमजोर सम्बन्ध, असमान वितरण, बढ्दो अनौपचारिक क्षेत्रको हिस्सा लगायतका कारण मुलुकको आर्थिक विकासको यात्रामा चासो र चिन्ता थपिएको छ । पन्ध्रौँ पञ्चवर्षीय योजनाले लिएको लक्ष्य एवम् उद्देश्य पूरा गर्न, समग्र मुलुकको सन्तुलित आर्थिक विकास गर्न, सर्वसुलभ पूर्वाधार निर्माण गर्न, अन्तर्राष्ट्रिय सम्बन्धको विकास, मानव पुँजी निर्माण तथा उपयोग, उच्च एवम् दिगो उत्पादन तथा उत्पादकत्व वृद्धि र समतामूलक राष्ट्रिय आय वृद्धि सहित आगामी २० वर्षका लागि मुलुकको दीर्घकालीन लक्ष्यहरू हासिल गर्न वित्तीय प्रणालीको भूमिका महत्त्वपूर्ण रहन्छ । मुलुकको आर्थिक विकास वित्तीय क्षेत्रका नीति तथा रणनीति र आर्थिक, सामाजिक एवम् वातावरणीय दिगो विकासका तीन ओटा खम्बाहरूको कार्यसूचीको कार्यान्वयनमा भर पर्दछ । वर्तमानको आवश्यकतामा कुनै सम्झौता नगरी भावी पुस्ताको आवश्यकता पूरा गर्नको लागि विनास विनाको विकास नै दिगो विकास हो। राष्ट्रको आर्थिक विकासका लागि वित्तीय प्रणालीमा रहेको सम्पत्ति र दायित्वको उचित परिचालन गरी रोजगार, आय, उपभोग, बचत र उत्पादनलाई प्रोत्साहन गर्न, गरिबी घटाउन, वातावरण व्यवस्थापन, समावेशी विकास, सुरक्षित खानेपानी, स्वास्थ्य, शिक्षा आदिको क्षेत्रगत सम्बोधन गर्न र अन्तर्राष्ट्रिय समुदाय समक्ष गरेका प्रतिबद्धताहरू पूरा हुने आर्थिक विकासको खाँचो छ ।
Two Interpretations of Spring and Autumn Annals[春秋] in the Mid-Joseon Period
Authors:   THE  TAEDONG  CENTER  FOR  EASTERN  CLASSICS, LEE Won-seok
Published: July 2022

This article attempted to investigate the pluralistic aspects of the interpretation of Spring and Autumn[『春秋』] in the middle of the Joseon Dynasty, focusing on A Detailed Commentary on Spring and Autumn Annals[春秋瑣說] of Shin Min-il (申敏一) and the criticism of it by Jo Ik(趙翼). Duke Yin[隱公]’s enthronement and death were significant events that caused various controversies regarding the core principles of patriarchal clan system[宗法制] during the Spring and Autumn period, so it was subject to intensive review by later researchers. Regarding Duke Yin’s behavior, Gongyang Commentary On Spring And Autumn Annals[春秋公羊傳] and Guliang Commentary On Spring And Autumn Annals[春秋穀梁傳] show the opposite attitude, and there are two issues. The first is the possibility of a conflict between the hierarchical principle of patriarchal clan system and filial piety[孝], and the second is the possibility of a conflict between the private nature of the act of giving favors and the public nature of feudalism. From the basic point of view of defending Duke Yin, Gongyang Commentary On Spring And Autumn Annals praised his willingness to hand over the country to his younger brother as well as his ability to judge the political situations, but Guliang Commentary On Spring And Autumn Annals downgraded Duke Yin to a person buried in the private sector. The evaluation of Duke Yin by the Hu Anguo[胡安國] is generally consistent with that of Guliang Commentary On Spring And Autumn Annals[春秋穀梁傳]. This is because Hu Anguo[胡安國] also criticized Duke Yin’s actions, which had abdicated the country as a private matter. Shin Min-il stood up for Duke Yin, criticizing Hu Anguo’s assessment of Duke Yin. At this time, Shin Min-il emphasized the principle of filial piety more, emphasizing that Duke Yin tried to comply with the intention of his father, Duke Hui[惠公], rather than his will to hand over the country to his younger brother. He saw that the latter should be prioritized when the principle of succession and filial piety conflict. Of course, he argued that it should not be unilaterally done, but a “scale[權衡]” to adjust the two principles is necessary, and all actions should be judged according to the “principle of natural human feelings[情法]”. On the other hand, Jo Ik emphasizes the hierarchy principle of patriarchal clan system and the publicity of the feudal system, which is consistent with Hu Aaguo and Guliang Commentary On Spring And Autumn Annals. In fact, Shin Min-il’s emphasis on “principle of natural human feelings” is actually based on Zhu Xi’s interpretation of Spring and Autumn Annals. This is because Zhu Xi also showed aspects of interpreting the difficult phrases of Spring and Autumn Annals in light of “principle of natural human feelings” in many ways. On the other hand, Jo Ik expressed concerns about Shin Min-il’s emphasis on the concept of “principle of natural human feelings”, but Shin Min-il must have been proud that his method could be supported by Zhu Xi.
الملكيات والأوقاف في مدينة بيت المقدس والمسجد الأقصى
Authors: BARAIJIA Issa
Published: July 2022

اتخذ الصراع على الأرض بين الفلسطينيين والاحتلال الصهيوني عدة جوانب، لعل من أهمها إثبات الأحقية في الأرض. ولـمَّا شكَّلت الملكيات والأوقاف بكافة أشكالها في فلسطين جزءا مهما لقدسية أراضيها، تطلب الأمر من الفلسطينيين اللجوء إلى تثبيت وتوثيق جميع الأوقاف والأملاك الإسلامية والمسيحية على حد السواء لحمايتها من المصادرات والاعتداءات الإسرائيلية. وفي سبيل تحقيق هذا الهدف يتطلب الأمر البحث في الأرشيف العثماني الذي يعد المصدر الأساسي في هذا الموضوع.
O Fascismo: mais do que nunca, um desejo presente
Authors: Feitoza Frederico
Published: July 2022

Diante da efetividade da polícia e da biopolítica no campo social, devemos atentar para o aprimoramento e a elasticidade do fascismo para além de sua versão oficial institucionalizada que remete ao século XX. Em que medida o desejamos ainda? No texto que ofereço, forneço uma fundamentação teórica que nos permite entender o desejo fascista como um fenômeno que se funda historicamente e estabelece uma herança cultural, no campo da estética, para as autopropaladas democracias neoliberais.