bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS KLASIFIKASI MENGGUNAKAN REGRESI LOGISTIK BINER DAN ALGORITMA NAÏVE BAYES CLASSIFIER PADA PENYAKIT HIPERTENSI
Authors: Sahila Riza , Widiharih Tatik , Utami Iut Tri
Published: February 2025

Hypertension is a primary cause of cardiovascular disease. Approximately 60% of people with hypertension are in developing countries, including Indonesia. In this analytical study, classification will be carried out to prove the status of hypertensive patients or not hypertensive. The classification method used is Binary Logistic Regression and Naïve Bayes Classifier. Binary Logistic Regression is Logistic Regression with the response variable being binary. Naïve Bayes Classifier namely predicting future opportunities using previous data. The factors used in this study were gender, age, height, and weight. The greatest accuracy of classification results is in the proportion of 90%:10%. The accuracy of the classification produced by Binary Logistic Regression method resulted in a sensitivity of 93.33%. The classification accuracy obtained by the Naïve Bayes Classifier with a sensitivity of 63.64%. This shows that the Binary Logistic Regression method has a better sensitivity value.Keywords:  Hypertension, Classification, Binary Logistic Regression, Naïve Bayes Classifier, Sensitivity.
ANALISIS MODEL REGRESI COX PROPORTIONAL HAZARD PADA DATA KETAHANAN HIDUP PASIEN HEMODIALISA MENGGUNAKAN METODE BRESLOW
Authors: Saragih Risky Trywita , Wuryandari Triastuti , Fakhriyana Deby
Published: February 2025

Chronic Kidney Disease is a pathophysiological stage with various etiologies which causes a progressive and irreversible decline in kidney function that culminates in kidney failure, thus requiring routine kidney therapy. Hemodialysis (HD) is one of the therapies for people with kidney disorders who have poor kidney function. The Cox Proportional Hazard Regression Model is a commonly used model in survival analysis to analyze time to events or between events. In the survival analysis data, there may be ties or joint events, so in this study Cox Proportional Hazard regression was used with the Breslow approach. This study aims to determine the factors that affect the survival time of hemodialysis patients, especially patients at Vita Insani Pematang Siantar Hospital, North Sumatra Province. Based on the results of the analysis obtained that hemodialysis patients who have high systolic blood pressure ≥ 140 chances of failure to survive greater than hemodialysis patients with normal systolic blood pressure. Therefore, hemodialysis patients with high systolic blood pressure need special attention.
Beyond the Classroom Walls: Metacognitive awareness in traditional and online setting
Authors: Miháliková Radka
Published: February 2025

Objective – The aim of this study is to assess and compare the metacognitive awareness of university students in online and in-person learning environments. Secondly, the study aims to explore the students’ preferences for online and in-person learning to compare themetacognitive awareness of students based on their preferences.
Methods – A total of 79 university students completed the Metacognitive Awareness Inventory, providing self-reported data on their metacognitive awareness. The study used a paired sample t-test to compare mean scores of metacognitive awareness between online and in-person classroom settings. Additionally, participants evaluated their experiences with online and in-person learning using a pairwise comparison as a scaling method.
Results – The t-test results indicate statistically significant differences in metacognitive awareness between online and in-person classroom settings. Specifically, significant differences were found in declarative knowledge, procedural knowledge, conditional knowledge, planning, information management strategies, monitoring, debugging strategies, and evaluation of learning. Students showed higher levels of metacognitive awareness across all facets in traditional in-person learning setting. Descriptive analysis of scaling pairwise comparison revealed that online learning was strongly preferred for comfort, while in-person learning was preferred modality for motivation to study and active participation. In oppose to t-test results, ANOVA did not reveal significant differences in metacognitive awareness based on students’ preferences in online nor in traditional learning settings.
Conclusions – The results provide valuable information on the metacognitive awareness and preferences of the students in two different learning environments.
Rola społeczna mediów cyfrowych w orędziach papieża Franciszka z okazji Światowych Dni Środków Społecznego Przekazu
Authors: Koper Damian
Published: February 2025

Pope Francis, in his messages on the occasion of the World Day of Social Communications, addresses currently important issues concerning communication in the digital world. Appreciating the achievements in the field of new media, he points to the need for media education. In this article, I have used the method of analyzing the content of eleven messages of Pope Francis in terms of the social role of digital media, subjecting them to synthesis and critical evaluation. The constant development of the media affects the relevance of the issue I am discussing. The Pope’s teaching expresses the position of the Church regarding the need for in-depth reflection on the proper understanding of the media’s tasks and role in shaping society.
İNTERNETTE YER ALAN TÜKETİCİ YORUMLARININ SATIN ALMA NİYETİNE ETKİSİ
Authors: Yılmaz Ali Can , Demirkol Celal
Published: February 2025

Günümüzde pazarlama ve reklam faaliyetleri sayıca artsa da nitelik açısından tartışılır konuma gelmektedir ve bu süreçte tüketiciler samimi görebileceği fikirlere daha çok ihtiyaç duymaktadır. Bu bağlamda bireyler kimi zaman internet ortamında tanımadıkları kişiler tarafından yazılan ürün yorumlarına başvurabilmektedir. Sürecin elektronik ortamda gerçekleşmesi ise elektronik ağızdan ağıza iletişimin satın alımlardaki etkisini gündeme getirmektedir. Gerçekleştirilen bu araştırmada elektronik ağızdan ağıza iletişimin satın alma niyetine yönelik etkisi incelenmiştir. İlave olarak, demografik değişkenlerin de düzenleyici rolü incelenmiştir. Tekirdağ ilinde gerçekleştirilmiş olan çalışmanın örneklem grubunda, kolayda örnekleme yöntemiyle 384 katılımcı yer almıştır. Veriler ise anket tekniğiyle toplanmış olup, bilgisayar ortamında kaydedilmiştir. Yapılan analizler neticesinde, elektronik ağızdan ağıza iletişimin nicelik ve nitelik boyutlarının satın alma niyetini etkilediği görülmüştür. Güvenilirlik boyutunun ise modeli açıklamada bir öneme sahip olmadığı sonucuna ulaşılmıştır. Çalışma kapsamında ayrıca, niceliğin satın alma niyetine olan etkisinde, alışveriş için ağırlıklı olarak tercih edilen mecranın yanı sıra, internetten aylık alışveriş sıklığı ve de yaş aralığının düzenleyici rol gösterdiği neticesine ulaşılmıştır.
GÖNÜLLÜ YÖNETİMİ ALANINDA YAPILAN ÇALIŞMALARIN BİBLİYOMETRİK ANALİZİ
Authors: Sayın Züleyha
Published: February 2025

Önemli bir güç olarak değerlendirilen sivil toplum örgütleri, kamuoyu oluşturma, toplumsal farkındalık, gerekli görülen konularda yapılan iyileştirmeler ve boşluk görülen alanlarda çalışmalar yapmaktadır. Sivil toplum örgütleri bu çalışmaları hayata geçirirken de profesyonel çalışanlar ve gönüllüler gibi iki temel insan kaynağından faydalanmaktadırlar. Böylesi önemli bir insan kaynağının temini, sivil toplum örgütleri içerisinde doğru konumlandırılmaları, devamlılıklarının sağlanması gönüllü yönetimi konusunun önemini ortaya çıkarmaktadır. Bu sebeple bu araştırmanın amacı gönüllü yönetimi konusunda alanda yaşanan değişimi ve odaklanmaları ortaya çıkararak yazında bu konuda yapılacak çalışmalara yön göstermektir. Bu kapsamda Web of Science veri tabanında yer alan 283 makale VOSviewer programı kullanılarak bibliyometrik analiz yöntemi ile incelenmiştir. Alanda yapılan çalışmaların en çok ABD’de olduğu, 2009 yılından bu yana yapılan çalışma sayılarında artış yaşandığı, yayınların daha çok sivil toplum alanında yayın yapan dergilerde yer aldığı gibi bulgulara ulaşılmıştır. Alandaki yayınlar bütünsel bir bakış açısıyla incelendiğinde gönüllü yönetiminin klasik insan kaynakları yaklaşımının ötesine geçen “profesyonel bir gönüllü” şeklinde yaklaşım zorunluluğu ortaya çıkmaktadır.
Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action
Authors: Aurangzeb Sana , Aurongzeb Muhammad , Shamim Shahbaz , Rashid Yasmeen , Khan Khalid Mohammed , Aziz Tariq , Alharbi Metab , Alasmari Abdullah F.
Published: February 2025

The HslVU enzyme complex, a proteasomal analog found in bacteria, consists of two components, i.e., the HslV protease and the HslU ATPase. These proteins come together to form a functional enzyme complex, where the C-terminal helix of each HslU subunit is inserted into the binding pocket of each HslV dimer. This interaction leads to the activation of the HslV protease through allosteric mechanisms, enabling its enzymatic function. This bacterial complex is reflected as an attractive target for drug development due to its presence in disease-causing microorganisms and concurrent absence in humans. The objective of this research was to identify certain promising drug candidates that could excessively stimulate the HslV protease, leading to uncontrolled protein breakdown in the pathogens. Four dihydropyrimidone derivatives have been identified as potential activators of HslV protease exhibiting high docking scores, favorable binding patterns, and significant in vitro activation capabilities. These compounds have demonstrated effective dose 50 values within the sub-micromolar range, i.e., 0.4–0.58 µM. Normal mode analysis investigations provided additional confirmation regarding the stability of the conformational interactions between the HslV protease and the active compounds. In addition, the predicted absorption, distribution, metabolism, excretion, and toxicity properties of these lead compounds remarkably demonstrated their considerable drug-like and non-toxic qualities. This study not only presents more potent small non-peptide activators of the HslV protease but also enhances the understanding regarding the mechanism of HslVU complex activation via small non-peptidic molecules.
“I see wonderful things!” Socio-cognitive experience of Cypriot graffiti in ancient Egypt
Authors: Pestarino Beatrice
Published: February 2025

This article analyses Cypriot graffiti in Egypt engraved by tourists and mercenaries in the Archaic and Classical periods (sixth through fourth centuries BC). These graffiti were inscribed on walls of majestic monuments, e.g., the pyramids in Giza and the temples of Karnak and Abydos. They were written in different languages and scripts all employed on the island, such as Cypriot-syllabic Greek, Eteocypriot – an indigenous language still undeciphered – alphabetic Greek and Phoenician, spread throughout the city-kingdoms into which Cyprus was subdivided. The examination is conducted through a socio-cognitive approach, moving beyond previous scholarship which exclusively focused on the graffiti’s concise texts – often limited to the names and provenance of the writers. By comparing Cypriot Egyptian graffiti with contemporary graffiti and twenty-first-century graffiti written in Cypriot-syllabic script, the analysis will shed light on the role of socio-political environment and landscapes in triggering individuals’ – in this case Cypriots’ – cognitive-behavioral responses which lead them to write these texts. This pioneering approach will allow a better understanding of the underlying reasons why these graffiti were engraved and in which locations. The investigation will provide a better knowledge of the origins of the Cypriot writers, level of literacy, and of their role in society (e.g., insiders vs. outsiders), shedding light on communities that would otherwise be unknown. Furthermore, this study lays the foundations for developing an innovative methodology applicable to epigraphic studies, based on integrating landscape interactions and visual impacts to more traditional examination strategies.
Pragmatic characteristics of diminutive adjectives in Kazakh and English languages
Authors: Manasbayeva Nagima , Sabitova Leilya
Published: February 2025

The study aimed to investigate the functional-pragmatic and communicative-pragmatic use of morphological and syntactic diminutive resources of Kazakh and English in the example of artistic contexts. The following methods were used: comparative-comparative, morphological-syntactic, communicative-pragmatic, analytical-synthetic, and contextual. This paper analysed the main morphological and syntactic resources used for word formation of diminutive adjectives in Kazakh and English languages. In particular, the results of the study showed that synthetic means (use of suffixal morphemes with diminutive semantics) and analytical means (use of special lexemes with diminutive semantics) are frequent in Kazakh. It was determined that suffixal morphemes to express the diminutiveness of adjectives were most often used to warn addressees about the properties of objects and phenomena, to soften categorical evaluation in Kazakh, to diminish the attributes of the object, to demonstrate the incompleteness of the attribute in English. This work can be used in the spheres of communicative linguistics, linguistic pragmatics, word formation, and morphology.
Advances in research on the impact of exosomal miRNAs on liver metastasis of colorectal cancer
Authors: Zhong Xuemei , Guo Dan
Published: February 2025

Colorectal cancer (CRC) is a prevalent malignancy, and its liver metastasis is a key factor leading to patient death. Research has shown that exosomal microRNA (miRNA) plays an important role as a mediator of communication between tumor cells and other cells in the growth, invasion, and metastasis of cancer cells. It also plays a critical role in the occurrence and development of CRC liver metastasis (CRC-LM). This article reviews the biological functions of exosomal miRNA and explores its significant involvement in the mechanism of CRC-LM. It also focuses on the latest progress of extracellular vesicle miRNA in the study of CRC-LM, providing new ideas and methods for future treatments.
Effect of AO 4426 on damping properties of PVA/CPE-AO 2246
Authors: Sheng Jiang , Yong Zhang
Published: February 2025

To investigate the influence of AO 2246 and AO 4426 on the damping properties of polyvinyl alcohol/chlorinated polyethylene (PVA/CPE) composites, a series of composites were prepared by adding AO 4426 into PVA/CPE-AO 2246 under the constant mass ratio of hindered phenol in the composites. The dynamic mechanical properties and microstructure of materials were investigated by DMA, DSC, SEM, and FT-IR. The results showed that a new damping peak appeared near 50 °C by adding AO 4426, which indicated phase separation between AO 4426 and the matrix occurred. With the increase of AO 4426, the damping peaks in the low-temperature section were improved. The value of low-lying region between the double damping peaks, when the hindered phenol coexisted was higher than that of the composites containing only AO 4426, which indicated that the damping temperature domain of the composites was effectively broadened. At the melting temperature of AO 4426 microcrystalline and AO 2246 microcrystalline, no obvious peaks were observed simultaneously, indicating that the hindered phenols inhibited the crystallization of each other.
Role of metal-organic frameworks (MOFs) in electrochemical energy storage devices including batteries and supercapacitors
Authors: Rashid Khashia , Omeema Umme , Raza Abuzar Hasnain , Manzoor Ansa , Abbas Muhammad Sajid , Mustafa Ghulam , Iqbal Muhammad Adnan , Iram Ghazala , Akram Manahil , Ateeq-Ur-Rehman
Published: February 2025

Better energy storage systems are becoming more and more in demand as electric cars, portable electronics, and renewable energy sources become more prevalent. Supercapacitors and batteries, such as lithium-ion batteries (LIBs), sodium-ion batteries (NIBs), lithium sulfur/air batteries, and lithium selenium batteries, are major components of these technologies; yet, stability, cycle life, and energy density are some of the challenges they face. MOFs have emerged as a new material that can solve the problems with unique structural properties. Large surface area and porosity are properties of MOFs which improve the energy density, life cycle and stability of energy storage devices when MOF are used as alectrode material in these devices.This paper analyzes and focuses on the application of MOFs in supercapacitors, LIBs, and SIBs, in which it emphasizes improvement in terms of stability and performance. This review article ends with an overview of the important challenges and the prospects for future research to fully meet the promise of Metal organic frameworks in energy storage applications.
Growth Hormone Alters Remapping in the Hippocampal Area CA1 in a Novel Environment
Authors: Haugland Kamilla G. , Jordbræk Sondre Valentin , Knutsen Erik , Kjelstrup Kirsten B. , Brun Vegard H.
Published: February 2025

Growth hormone (GH) is a neuromodulator that binds to receptors in the hippocampus and alters synaptic plasticity. A decline in GH levels is associated with normal aging, stress, and disease, and the mechanisms proposed involve the hippocampal circuit plasticity. To see how GH affects the hippocampal neural code, we recorded single neurons in the CA1 region of male Long–Evans rats with locally altered GH levels. Rats received injections of adeno-associated viruses into the hippocampus to make the cells overexpress either GH or an antagonizing mutated GH (aGH). Place cells were recorded in both familiar and novel environments to allow the assessment of pattern separation in the neural representations termed remapping. All the animals showed intact and stable place fields in the familiar environment. In the novel environment, aGH transfection increased the average firing rate, peak rate, and information density of the CA1 place fields. The tendency of global remapping increased in the GH animals compared with the controls, and only place cells of control animals showed significant rate remapping. Our results suggest that GH increases hippocampal sensitivity to novel information. Our findings show that GH is a significant neuromodulator in the hippocampus affecting how place cells represent the environment. These results could help us to understand the mechanisms behind memory impairments in GH deficiency as well as in normal aging.
Ecological species groups and interspecific associations of dominant woody species in a seasonal tropical forest of Laos
Authors: Quy Nguyen Van , Dien Pham Van , Thinh Nguyen Van , Long Ngo The , Manh Vu , Mai Trinh Hien , Cuong Le Van , Trang Pham Thanh , Hop Nguyen Van , Tuan Nguyen Thanh , Phomphoumy Khamphet , Luu Do Phong , Hai Nguyen Hong
Published: February 2025

The study of ecological species groups (ESGs) and interspecific interactions offers important insights into the mechanisms that drive tree species coexistence and enhances our understanding of plant community structure, function, and taxonomy. This study aimed to identify ESGs within a seasonal tropical forest in Phou Khao Khouay National Park, located in central Laos, and to investigate the key environmental factors influencing their distribution. Additionally, the study analysed community stability and interspecific associations among woody species using various statistical techniques, including Variance Ratio (VR), chi-squared tests, Association Coefficients (AC), and percentage of Co-occurrence (PC). To collect data, thirty-two permanent plots, each covering an area of 2500 m² (50 × 50 m), were established. In each plot, floristic data and species abundance were recorded, along with soil samples from two depths (0–10 cm and 10–20 cm) for physicochemical analysis. Vegetation data were classified using Two-Way Indicator Species Analysis (TWINSPAN), and differences between ESGs were evaluated using Analysis of Variance (ANOVA). Indicator Species Analysis (ISA) was applied to identify key species for each ESG, while Canonical Correspondence Analysis (CCA) was employed to explore the relationships between ESGs and environmental variables. The results revealed that the woody plant communities in the study area were relatively stable, exhibiting predominantly positive interspecific associations. Additionally, the distribution of the fosur identified ESGs showed a strong correlation with topographical factors – such as elevation, aspect, and slope – and soil properties, including pH, organic matter content, cation exchange capacity, total nitrogen, phosphorus, potassium, and soil texture. These findings underscore the importance of recognizing microhabitats that support the growth and conservation of woody plant species in Phou Khao Khouay National Park, offering valuable insights for future ecological research and conservation initiatives.
Ochronotic arthropathy: skeletal manifestations and orthopaedic treatment
Authors: Salem Khaled Hamed , Elmoghazy Alyaa Diaa
Published: February 2025

Alkaptonuria is an extremely rare disorder of tyrosine metabolism caused by an autosomal recessive enzymatic deficiency of homogentisic acid (HGA) oxidase, causing its accumulation in collagenous structures, especially in hyaline cartilage.

It is characterized by a triad of homogentisic aciduria, bluish-black discoloration of connective tissues (ochronosis) and arthropathy of the spine and large weight-bearing joints.

Several clinical manifestations were described including coronary and valvular calcification, aortic stenosis, limited chest expansion, and renal, urethral and prostate calculi as well as ocular and cutaneous pigmentation.

Skeletal affection usually presents as spondylotic changes of the spine. The knee is the most common peripheral joint to be involved. Enthesopathy or tendon ruptures may occur, and reduced bone density is not unusual.

A low-protein diet and ascorbic acid may reduce HGA levels. Nitisinone can safely and effectively reduce HGA production and urinary excretion.

In severe ochronotic arthropathy, joint arthroplasty can offer reliable pain relief and excellent functional outcomes. Cementless fixation is successful in young patients.
Total knee arthroplasty following previous hardware implantation: do hardware removal strategies influence periprosthetic joint infections? A systematic review and meta-analysis
Authors: De Mauro Domenico , Comisi Chiara , Festa Enrico , Ascione Tiziana , Mariconda Massimo , Balato Giovanni
Published: February 2025

Purpose

Total knee arthroplasty (TKA) in patients who underwent previous knee surgeries can be a challenging procedure both technically and for the complication rate. Conversion TKA is affected by a higher risk of infection compared to primary TKA. The aims of this meta-analysis are i) to compare the infectious risk among patients undergoing TKA after a prior hardware implantation, evaluating removal vs maintenance of the hardware, and ii) within the removal group, to compare staged vs concurrent procedure.

Methods

In accordance with the PRISMA guidelines, a systematic literature review was conducted up to January 2024. The review was registered in the PROSPERO database: CRD42024510444. The inclusion criteria comprised the following: i) patients aged 18 years or older, ii) individuals who had undergone total knee replacement and iii) those with a history of prior nonabsorbable hardware implantation. The pooled incidence of periprosthetic joint infections (PJI) was reported using odds ratios with corresponding 95% confidence intervals (CIs).

Results

The investigation of database and references identified 284 studies. PJI risks differed significantly among groups, with a higher risk in the removal group (z = 3.5630, P = 0.0004). Furthermore, within the removal group, the risk of PJI was lower in cases of staged removal compared to concurrent removal (z = 2.0931, P = 0.0363).

Conclusions

TKA following a previous knee hardware implantation indicates a higher PJI risk when the hardware is removed compared to leaving it in place. If hardware removal is necessary, staged removal is recommended. The presence of minor hardware is the only scenario where, if removal is necessary, one-stage approach is preferred.
Teorías Declaradas y Teorías en Acción sobre Evaluación: Análisis de Cuatro Experiencias
Authors: Martinez Milgian
Published: February 2025

Evaluar el aprendizaje es un elemento clave en la formación de estudiantes universitarios, por lo que resulta fundamental analizar las perspectivas y prácticas evaluativas del profesorado. En este artículo nos proponemos compartir las experiencias de cuatro docentes, según lo que piensan, sienten y declaran sobre la planificación de la enseñanza, los contenidos didácticos, la metodología y la evaluación, y lo que en realidad llevan aplican en sus aulas. Para ello seguimos un abordaje cualitativo, a través del estudio de caso, aplicándose entrevistas, grupos focales, análisis documentales de guías docentes, y observaciones de clase con un grupo de 17 profesores pertenecientes a siete distintas áreas del conocimiento, de los cuales exponemos las experiencias de dos del Departamento de Ciencias Sociales y dos de Ingeniería. Los resultados evidencian que, aunque en su discurso reconocen la importancia de la evaluación formativa, en su práctica persisten enfoques tradicionales centrados en la medición, con escasa participación estudiantil, siendo más coherentes los docentes de Historia; por su parte, los de Ingeniería reportaron mayores divergencias. En ese sentido, identificamos necesario fortalecer la formación, reflexión y auto-cuestionamiento de sus prácticas para lograr mayor correspondencia entre sus concepciones y sus acciones, que redunde en aprendizajes significativos en los estudiantes.
ДИСПЕРСИЯ ТЕМПЕРАТУРЫ ВОЗДУХА В УСЛОВИЯХ ТЕМПЕРАТУРНОЙ ИНВЕРСИИ
Authors: ГЛАДКИХ В.А. , КАМАРДИН А.П. , НЕВЗОРОВА И.В. , ОДИНЦОВ С.Л.
Published: February 2025

Рассмотрено влияние вертикальных и горизонтальных турбулентных потоков тепла на величину дисперсии температуры воздуха в условиях температурных инверсий различной интенсивности. Показано, что неучет горизонтальных турбулентных потоков тепла в этих условиях может быть причиной существенной недооценки высоты слоя перемешивания существующими моделями.

The effect of vertical and horizontal turbulent heat fluxes on the air temperature variance under conditions of temperature inversions of different intensity is considered. It is shown that the neglect of horizontal turbulent heat fluxes under these conditions in the existing models can lead to significant underestimation of the mixing layer height.
Charcoal-production, Air Pollutant Impacts on Ambient Environment and Associated Health Risks: A Systematic Review
Authors: Okimiji Oluwaseun Princess
Published: February 2025

Charcoal is a widely utilised fuel produced from the carbonisation of organic materials, such as wood and other biomass sources. Regrettably, airborne contaminants from traditional charcoal producing techniques can negatively impact human health and the environment. This research explore air pollutant emissions from traditional charcoal producing methods and their impacts on human health and the environment. This study utilised a qualitative synthesis methodology, incorporating case studies, archival research, and discourse analysis, to elucidate the impacts of charcoal production. The results demonstrate that the traditional charcoal production method results in substantial carbon loss from fuelwood and emits by-products of incomplete combustion, exacerbating serious health risks and degrading air quality associated with community health problems. Empirical evidence indicates that the majority of charcoal manufacturing workers lack awareness of the health risks associated with their working circumstances and the respiratory problems they face. Unsustainable environmental practices highlight the social and ecological repercussions of charcoal production. It is advisable to apply air pollution mitigation methods around charcoal kiln facilities to protect environmental and community health. The Environmental Protection Agency must actively implement effective oversight and integrated management to improve air quality and safeguard communities from air hazards. This study recommends testing high-efficiency technologies in communities capable of maintaining and assessing their effects on environmental degradation. Both governmental entities and humanitarian organisations should prioritise educational activities centred on effective land management approaches, as this study's findings suggest.
Sleep Study Patterns in Children With Down Syndrome at Different Ages
Authors: Thamkittikun Chalisa , Tovichien Prakarn , Udomittipong Kanokporn , Chotinaiwattarakul Wattanachai , Tiamduangtawan Pinyapach , Sathienkijkanchai Achara , Tanphaichitr Archwin
Published: February 2025

OBJECTIVES

Down syndrome (DS) is a common genetic syndrome associated with a higher risk for sleep-disordered breathing. We aimed to reveal the age-related developmental difference in sleep architecture and polysomnographic phenotypes and identify the predictors of severe obstructive sleep apnea (OSA) in children with DS.

METHODS

This cross-sectional study included children aged 3-18 with DS who underwent diagnostic polysomnography from 2013-2023. We collected demographic data, sleep symptoms, and polysomnographic results. We analyzed the prevalence of sleep-disordered breathing categorized by age group and used multivariable logistic regression to identify predictors of severe OSA.

RESULTS

Among 95 children, 56.8% had severe OSA and 24.2% had sleep-related hypoventilation. Of those with OSA, 50.5% had positional OSA, and 55.8% had rapid eye movement (REM)-related OSA. Categorized by age groups, children aged 12 -18 years had the highest rates of sleep-disordered breathing compared to other age groups: 75.0% for severe OSA and 82.6% for positional OSA. Age (adjusted OR (95% CI) = 1.24 (1.08-1.43), p = 0.002) and tonsillar hypertrophy (adjusted OR (95% CI) = 3.28 (1.22-8.86), p = 0.019) were significantly associated with severe OSA.

CONCLUSIONS

Sleep-disordered breathing was most frequently diagnosed in children with DS aged 12-18 years compared to other age groups, with a positive correlation between age and OSA severity. Our data support proper surveillance polysomnography for those with tonsillar hypertrophy and during adolescence, even for children with DS who had an initial negative PSG by four years of age.
Journalism’s ethical mission in a crisis of cultural ethos. Proposing a 10-paradigm shift in the pre-political foundations of journalism practice
Authors: Codina Mónica
Published: February 2025

Following the Kuhnian theory of scientific development, this essay proposes a 10-paradigm shift regarding the pre-political foundations of journalism practice to address the crisis of cultural ethos in Western liberal democracy societies. It aims to reshape some of the current paradigms that are at the root of the ethical limitations of journalism in Western institutions. To do so, this essay explores the insights of some twentieth-century scholars who, by closely targeting specific failings of liberalism, offer a novel theoretical approach that broadens the meanings of basic pre-political concepts. Their insights offer elements that allow reshaping some 21st-century social assumptions –paradigms– rooted in the current form of the liberal West’s society that sustain contemporary social norms and practitioners’ performance. A full account of each paradigm shift is beyond the scope of this article. Rather, the goal is to sketch a disruptive theoretical starting-point to address journalism’s ethical mission in a new social context and enhance practitioner reflexivity. Finally, I refer to the New Renaissance Project as the initiative to strengthen the ethical foundation of the pre-political paradigms that drive Western democratic institutions, including journalism, at the beginning of a new era.
Citation patterns, the Matilda effect and gender bias in communication & media Studies scientific output in Ibero-America (1980-2022)
Authors: Torrado-Morales Susana , Zamora-Medina Rocío , Olmos Maribel , Subtil Filipa
Published: February 2025

This article analyses diachronically the role of women in the field of communication & media studies in Ibero-America by studying the presence or absence of women in the bibliography of a selection of articles taken from 60 communication academic journals in 9 countries (Spain, Portugal, Brazil, Argentina, Mexico, Chile, Colombia, Ecuador and Peru) between 1980 and 2022. This study measures the degree of visibility of female scientists and their contribution and compares it statistically to that of their male counterparts by quantifying from a gender perspective the citation patterns of authors of the 484 scientific articles included in the study. The findings showed that the visibility of the female researchers-authors increased over time. Furthermore, an over-citation of publications by male researchers was also found. Last, in one of the periods analysed, in the years between 1996-2010, gender homophily was found, i.e., female researchers tended to cite more women than men during this period.
Identification and Characterization of Novel Bioactive Peptide From Red Seaweed (Pyropia vietnamensis) Proteins
Authors: Basri Nur Iliana , Amin Amiza Mat , Ahmad Fisal
Published: February 2025

Pyropia vietnamensis is one of the most abundant seaweeds in the Indo-Pacific region.  This study aimed to perform an in silico evaluation of P. vietnamensis proteins as potential precursors of bioactive peptides and to determine the novel peptide in terms of its half maximal inhibitory concentration (IC50) and the stability under controlled laboratory environment (in vitro) towards the dominant biological activity. The proteomic profiles of P. vietnamensis proteins were determined using LC-MS/MS analysis. Next, five proteins were chosen and employed for in silico analysis using the BIOPEP-UWM database. The in vitro characterizations of novel peptide were carried out using a dipeptidyl peptidase-IV (DPP-IV) inhibitor screening assay kit. In silico analysis revealed that DPP-IV and angiotensin-converting enzyme (ACE) inhibitors were the most potential bioactive peptides in P. vietnamensis proteins. Calpain 2, papain, pepsin (pH>2), and stem bromelain were predicted as the enzymes with the most potential to produce DPP-IV and ACE inhibitors. The novel peptides predicted were CFA, ACF, RFPS, DEWG, NYCL, CVPR, and DACF. The synthesized CVPR with an IC50 of 0.66 mg/ml exhibited stability at pH 3-7, 30-50 °C, and resisted gastrointestinal digestion. This study revealed P. vietnamensis proteins could offer health benefits due to the therapeutic potential with sustainable industrial applications on functional foods, nutraceuticals, and pharmaceuticals.
Generative Artificial Intelligence Integration for the Education of Islamic Communication and Broadcasting
Authors: Hartati Rahmi , Fujiantie Jerina , Ries Dyah Fitriyah
Published: February 2025

This research aims to explore the use of Generative Artificial Intelligence (AI) in lectures, examine the changes in learning culture and its impacts, and provide recommendations for optimizing the integration of Generative AI for students of Islamic Communication and Broadcasting at UIN Antasari Banjarmasin. The study involves lecturers and students as research subjects. Data collection techniques include in-depth interviews and documentation. The findings have revealed that students’ use of Generative AI for completing academic assignments has led to significant changes in lecture culture and dynamics. Students have become more active in asking questions and engaging in discussions. However, the use of Generative AI also presents various challenges and negative impacts, such as a decline in literacy skills and critical thinking. Therefore, it is crucial to provide lecturer guidance and mentorship, training on AI utilization, and policies that encourage collaboration between traditional and modern learning approaches.
Insights Into Landscape Perception and Appreciation Through Eye Movement Tracking
Authors: Tokmovtseva Anna D. , Akeleva Elizaveta V.
Published: February 2025

The variety of Russian natural scenery provides its natives with unique perceptive experience. Previous studies of this issue show cross-cultural differences among Russians and other cultures in their descriptions and emotional evaluation of landscapes. Our research aims to broaden the results of previous literature by exploring the connection between subjective judgements of landscapes by Russians and visual-spatial attention. Participants (n = 187; 136 females) were shown 102 pictures of native and foreign natural scenes and were asked to assess them by affective and location qualities using the semantic differential. During the picture presentation, eye movements were recorded with the usage of Tobii and Gazepoint eye-trackers. Our results suggest a link between individuals’ cognitive evaluation of landscapes and visual behavior. Duration of fixation correlated significantly with exotism and familiarity marks (p < .01) for the landscapes, indicating the novel visual information which is gained from an exotic scenery demands additional attention resources. The correlation was also found among average saccade duration, emotional and aesthetic assessments (p < .01). Therefore, the elongation of eye movement shifts might be a signifier of interest in the landscape. In the current study, we demonstrate the connection between visual attention and subjective judgment of a landscape image, which have not been shown previously for the Russian sample.
The conditionals in the Tsudakhar-Sirkhya language (the Dargin languages)
Authors: Mutalov Rasul
Published: February 2025

The article is devoted to the study of adverbial conditional clauses in Tsudakhar, one of the dialects of the Tsudakhar-Sirkhya language (the Dargin branch of the Nakh-Dagestanian languages). The main objective of the study is to identify and describe all polypredicative conditional constructions, to form a group of such sentences in terms of the facts of the situations. It was also supposed to determine the links of the main and subordinate clauses in the polypredicative construction and to describe the conditional conjunctions. As a result of the study, the main ways of link in the clauses of complex sentence are determined — the form of the predicate in subordinate clause and conditional conjunctions. The predicate of such constructions is used in the form of conditional or intentional mood, and the words rahlew, eger, nagah are used as conjunctions that express «if» meaning. According to the real conditions and the way of clause forming, conditional sentences in the Tsudakhar dialect are divided into three groups: the constructions expressing a real condition, a counterfactual condition and a hypothetical condition. Conditional forms are used as a predicate of the subordinate clause in constructions with a real condition; the predicate of constructions with a counterfactual condition; is the predicate of the pre-conditional form, and the intentional form is used to connect the subordinate and main clauses of the hypothetical condition. The results obtained will be useful in composing a comparative-historical grammar of the Dargin languages.
Cladistic analysis and redefinition of the Dasybasis Macquart s. str. (Diptera: Tabanidae) in the Neotropical region
Authors: González Christian R , Miranda-Esquivel Daniel Rafael
Published: February 2025

BACKGROUND The works of Lutz & Neiva, published 115 years ago in the Memórias do Instituto Oswaldo Cruz, are pioneering for the study of Neotropical Tabanidae. These studies emphasised the importance of biological collections and the description of species from the exploration of South American areas. Dasybasis Macquart, 1847 has traditionally been considered a large genus of tabanids restricted to the Australasian, Neotropical, and Andean regions. Dasybasis species exhibit a high degree of morphological similarity, making specific differentiation challenging. Moreover, some of these features are also present in other taxa, suggesting that they may not be homologous characters and should not be used to define the genus. OBJECTIVES This study aimed to assess the monophyly of Dasybasis and establish its major monophyletic groups. METHODS We conducted an implied weighting analysis using morphological characters, and wing landmarks from 91 terminal species. FINDINGS For the total evidence analyses, aligning with either Tabanus Linnaeus or Dasybasis appendiculata Macquart yielded slightly different trees. Classical morphology and total evidence topology aligned with D. appendiculata are the same, while differing from the total evidence topology aligned with Tabanus in two nodes. MAIN CONCLUSIONS Our results indicate that Dasybasis was not a monophyletic group, and that this name should be restricted to species with a distribution in Australasia; while Neotropical Dasybasis species are recovered in different clades. The genera Archiplatius, Pseudoselasoma, and Stypommia are revalidated. This study provides a revised phylogenetic framework for “Dasybasis” and related taxa, highlighting the need for a more nuanced understanding of morphological character evolution within the tribe Diachlorini.
Distribution of Anophelinae (Diptera: Culicidae) and challenges for malaria elimination in Brazil
Authors: Sallum Maria Anice Mureb , de Azevedo Thiago Salomão , Conn Jan Evelyn , Lourenço-de-Oliveira Ricardo
Published: February 2025

In 1909, Arthur Neiva published an article titled “Contribuição para os estudos dos dipteros. Observação sobre a biolojia e sistematica das anofelinas brasileiras e suas relações com o impaludismo”, highlighting the biology, ecology, and distribution of Anophelinae mosquitoes and the need for more taxonomic studies in Brazil. This came 11 years after Ronald Ross and Grassi demonstrated mosquito roles in transmitting Plasmodium to birds and humans. Despite considerable advances in the understanding of Anophelinae species, knowledge remains insufficient given the complexity of Brazil’s ecosystems, the intensified anthropogenic environmental changes since the mid-20th century, and the persistent public health challenges posed by malaria. This perspective article presents the distribution of Plasmodium vectors and potential vector species in Brazil using climate variables and a maximum entropy model. Geographical distribution maps of Anophelinae species, including putative species, are provided. The article also discusses the current knowledge of vector species distribution in relation to Brazil’s malaria elimination plan, along with the ecological and anthropogenic factors influencing vector distribution.
Microclima no Cenário de Floresta, Pastagem e Cidade no Sudoeste da Amazônia
Authors: Antonucci Bárbara , Neves Gustavo Zen de Figueiredo , Andrade Nara Luísa Reis de , Aguiar Renata Gonçalves , Webler Alberto Dresch
Published: February 2025

Resumo A expansão da fronteira agropecuária impulsionada pelo desmatamento da Amazônia tem promovido uma crescente conversão de uso e cobertura da terra, onde florestas estão sendo convertidas em pastagens, e/ou, com o aumento populacional, dando espaço à criação de cidades. Essa transformação na cobertura vegetal é refletida nos elementos climáticos, e consequentemente, na resposta aos fenômenos atmosféricos de microescala. As pesquisas mais recentes realizadas com dados observacionais do Programa de Grande Escala da Biosfera-Atmosfera na Amazônia (LBA) indicam alterações nos ciclos biogeoquímicos da água como reduções de chuvas entre regiões florestadas e não florestadas. No entanto, poucos estudam avaliam a conversão de florestas em cidades. Diante disso, este estudo tem como objetivo avaliar como a modificação da cobertura do solo de floresta para cidade e de floresta para pastagem impacta as variáveis micrometeorológicas no ano de 2017, em Rondônia, sudoeste da Amazônia. Os resultados apontam que os elementos climáticos são modificados com a antropização, no entanto, entre os ambientes antropizados não foram evidenciadas diferenças significativas. A conversão de florestas aumentou a amplitude térmica em aproximadamente 2 °C.
Coating based on Montmorillonite, essential oils, and amaranth to preserve mango
Authors: Ramos Evelyn Erika Pillco , Pacco-Huamani Maria Cecilia , Pizato Sandriane , Pinedo Rosalinda Arévalo , Cortez-Vega William Renzo , Delgado Grethel Teresa Choque
Published: February 2025

Abstract This study aimed to evaluate the coating based on Amaranthus flour (AF), montmorillonite, and three essential oils (clove, muña, and matico) to extend the shelf life of minimally processed mango. The mango cubes were divided into four different treatments. T1- control (uncoated mango), T2 (0.3% w/v of clove), T3 (0.3% w/v of muña), and T4 (0.3% w/v of matico). All treatments had 0.6% w/v Amaranth flour and 0.02% w/v montmorillonite (MMT) and were subjected to 5°C for 12 days. Water activity (Aw), pH, Total soluble solids, acidity, weight loss, color, texture, and antimicrobial activity were evaluated for each treatment. Matico treatment maintained pH and had the lowest count of yeast and mold forming units on mango (3.47 log UFC g-1). On the last day of storage, all coating treatments showed less weight loss and favorable results than the control. The matico treatment showed higher efficiency for mango preservation.
TREATMENT OF PATIENTS WITH GIANT CELL BONE TUMOR IN NORTHERN BRAZIL, IN 2020 AND 2021
Authors: Couto Filho Fernando Brasil do , Yonamine Eduardo Sadao , Magno Felipe Guimarães , Favacho-Silva Ana Beatriz , Brito Carlos Rafael Alves de , Brito Thiago Raphael Brasil
Published: February 2025

Abstract Objective: This study aimed to evaluate the profile of patients diagnosed with giant cell tumors treated at the Ophir Loyola Hospital. Method: An analytical study in the form of a retrospective cohort, conducted through a review of patient medical records and imaging exams of individuals treated at the hospital between January 1, 2020, and December 31, 2021. Result: A total of 19 patients were evaluated, with an average time of 10.5 months between diagnostic suspicion and the first consultation with the Orthopedic Oncology team. Conclusion: Among the patients studied, 73% were presented with advanced-stage disease, requiring aggressive surgical treatment with wide resection and replacement with an endoprosthesis. Level of Evidence II; Retrospective Prognostic Study.