bluuebunny/crossref_metadata_2025 huggingface dataset:
Discourse culture(s) of journalism: Newswriting in Dutch and Iranian handbooks
Authors: Rafiee Afrooz , Spooren Wilbert , Sanders José
Published: January 2023

Ten handbooks of journalism most-used in Dutch and Iranian (applied) universities were content-analyzed and compared for their instructions on (crime) newswriting and assumptions behind the given instructions. While Dutch handbooks consider ‘informing’ the optimal function of journalism and news, Iranian handbooks put emphasis on ‘increasing awareness’. Consequently, Dutch handbooks consider news as event and value information on facts, while Iranian handbooks aim for reporting the truth and consider news as on-going process. Specifically, as Iranian journalism handbooks value flexibility and creativity, they view storytelling style in news reports as the preferred journalistic genre and approach crime news as a special genre which should fulfill an educative function.
Monitoring the infection rate: Explaining the meaning of metrics in pandemic news experiences
Authors: Dahl John Magnus R. , Ytre-Arne Brita
Published: January 2023

The COVID-19 pandemic has brought forward questions of what citizens need and want from journalism in a global crisis. In this article, we analyse one particular aspect of pandemic news experiences: Preoccupation with monitoring metrics for COVID-19 infection cases, hospitalisations, and deaths, widely disseminated through journalistic news outlets. We ask why close monitoring of such metrics appeared meaningful to news users, and what these experiences can tell us about the role of journalism in the pandemic information environment. Our analysis draws on qualitative research conducted in Norway in 2020, finding users particularly devoted to monitoring metrics, both in early lockdown and during the second wave of COVID-19. To contextualize our findings, we draw on scholarship on emotional responses to data in the everyday, and on the social role of journalism. We argue that monitoring of infection rates is an expression of trust in the media as a provider of factual information, also expressed by those who are cynical towards other aspects of journalism, and we conceptualise this monitoring practice as a coping strategy to deal with the pandemic as an unknown and uncontrollable threat, involving difficult emotions of uncertainty and fear.
Walking with bread in Cairo: Ethnographic collaboration between a researcher and a research assistant
Authors: Barnes Jessica , Taher Mariam
Published: January 2023

This paper presents a mode of collaboration between a researcher and research assistant for ethnographic data collection. We describe our experience as a researcher, who previously conducted fieldwork in Egypt but is now largely situated in the United States due to having young children, and a Cairo-based research assistant, who conducted participant observation of everyday practices of buying and eating subsidized bread for the researcher’s book project on bread, wheat, and security in Egypt. We position our narratives of this process side-by-side, interspersed by joint reflections, addressing questions regarding power asymmetries, the distribution of benefits, and what makes research collaborations work well. We argue that partnering in observation brings the benefit of more than one way of seeing and thinking through data. Moreover, we propose that this form of collaboration can be an effective strategy for researchers for whom continuous presence in their fieldsite is not possible.
Towards a theory of reparative multiculturalism
Authors: Lambrecht Felix
Published: January 2023

Contemporary liberal states must provide an answer to the “question of cultural diversity”, requiring a principled way to determine which minority cultural practices a state must accommodate and support. (Liberal egalitarian) multiculturalism answers this question neatly by creating a dichotomy between national minorities and ethnic minorities (the national/ethnic “dichotomy” ). Where national minorities are entitled to extensive and far-reaching cultural rights, ethnic minorities are entitled to significantly fewer cultural rights and accommodations. This dichotomy is enacted through a distributive logic that allocates cultural rights to achieve equal individual autonomy. But the dichotomy is also influenced by the ways these groups were incorporated into the state. Their modes of incorporation are different and, thus, they have different requirements to achieve equally autonomous lives.

Critics have challenged multiculturalism by questioning this dichotomy . They have suggested that the dichotomy does not adequately capture differences in kinds of minority groups and their entitlements. This paper defends the dichotomy by offering a supplementary principle to liberal egalitarian multiculturalism: the reparative multicultural principle. This principle allocates cultural rights as part of reparative entitlements for historical and ongoing injustices committed against minority groups. Supplementing multiculturalism in this way more accurately captures the idea of the historical mode of incorporation that inspires the dichotomy and can help resolve some the objections to multiculturalism.
Visual lawfare: evidential imagery at the service of military objectives
Authors: Amir Maayan
Published: January 2023

While chemical attacks are rare and deemed an illegitimate form of warfare, the attempt to exploit international law in order to license military action is an eerily common custom. The practice of deploying a legal system to promote military objectives is now widely known as lawfare. In this article, the author focuses on what she calls visual lawfare, namely the weaponization of visual documentation used to provide evidence in order to either prove compliance, or to demonstrate violations, of international laws of warfare through appeal to a legal forum, in order to facilitate a military objective. Drawing on endeavours to affect the United Nations Security Council resolutions in the context of the Syrian Civil War, in addition to revisiting selected lawfare scholarship while providing the new concept of ‘visual lawfare’ itself, she expands on how visual evidence is employed or produced to sanction the lawful use of violence while citing international codes of conduct.
Couples living with Alzheimer’s disease talk about sex and intimacy: A phenomenological qualitative study
Authors: Albert Susan Carol , Eduardo Martinelli José , Costa Pessoa Maria Silvia
Published: January 2023

Objectives

To obtain a deeper understanding of the phenomenon of sexuality within the couple relationship when one of the partners has received a diagnosis of Alzheimer’s Disease. This study aimed to listen to the voices of both partners, and to investigate how their intimate relationship has been impacted by an Alzheimer’s diagnosis.

Methods

This study adopted a qualitative phenomenological approach, and the method used was Interpretative Phenomenological Analysis. The data was collected based on interviews with six couples, where one of the spouses had a mild to moderate Alzheimer’s diagnosis. The interviews were recorded and transcribed, and a detailed analysis of each interview was performed.

Findings

From the detailed analysis of the transcribed interviews, six main themes emerged: Sexual expression today; Alzheimer’s and sexuality; desire to be a sexual being; different sexualities; sense of couplehood; and uncertain future.

Conclusions

The findings of this study provide a deeper insight into experiences of sexuality for couples living with Alzheimer’s. Sexuality and intimacy of couples living with Alzheimer’s continues to be an important aspect of the relationship, and in general, the partners wish to have the opportunity to express their sexuality. The construction of a sense of couplehood during the marriage tends to be a significant factor to sustain the changes that arise in the intimate relationship because of the diagnosis. However, despite the growing recognition of the existence and importance of sexuality in later life, persons with Alzheimer’s have only recently starting to be recognized as sexual beings who wish to be heard.
The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow
Authors: Pravdivtseva Mariya S , Pravdivtsev Andrey N , Peters Sönke , Hensler Johannes , Larsen Naomi , Hövener Jan-Bernd , Jansen Olav , Wodarg Fritz
Published: January 2023

Background

Recently, a novel intrasaccular device (contour neurovascular system, contour) was introduced to treat intracranial aneurysms. Contour is placed at thе aneurysm neck and reduces the intraaneurysmal blood inflow. Contour comes in a range of sizes to target different aneurysms. The efficiency of altering flow with contour and the effect of device size have not yet been investigated. Therefore, we studied the effect of the device size with patient-based aneurysm models using 2D digital subtraction angiography (DSA).

Methods

Three patient-based aneurysm models with necks ranging from 2.7 to 9.7 mm were produced, providing standardized testing conditions. Contours with diameters of 5, 11, and 14 mm were implanted into the models, four of each size. 2D DSA images were acquired before and after implanting contour (15 frames/s, manual contrast injection). After injecting angiographic contrast agent, the DSA signal was recorded over time to calculate the contrast washout time (WOT), which is a measure of flow diversion efficiency.

Results

All contour devices caused contrast agent stasis and increased WOT in aneurysm sac ( p-value = 0.0005). The median relative WOT was largest for 5-mm contour (6.6 ± 3.2) and similar for 11-mm contour (3.4 ± 2.6) and 14-mm contour (3.2 ± 3.8). The implantation procedure might affect WOT values even for contours of the same size; the overall relative WOT ranged between 1.5 and 10.89.

Conclusion

The 5-mm contour showed the longest WOT value in our study, while no apparent difference between 11-mm contour and 14-mm contour was found.
Preload loss of CFRP bolted joint without rotation under transverse and axial loading
Authors: Yang Haoran , An Luling , Chen Xu , Zou Liyang
Published: January 2023

There are a large number of CFRP-steel bolted joints with jet nuts subjected to transverse and axial load in aircraft structures, which have passed standard testing of locking characteristics of fasteners under transverse loading conditions. This fastener has a great preload loss and no rotation loosening occurs. Based on the observation, we designed a biaxial loading experiment for CFRP bolted joint, and measured the preload and loosening angle under different initial preload. The biaxial research suggests that compared with the uniaxial loading condition, the preload loss is larger, the rotation is minimal and only appears in the early stage of test, and there are obvious indentations on the surface of CFRP panel. Embedment as an important factor leads to the preload loss due to the weak ability of CFRP panel suffering out of plane load. In order to study the effect of embedment, the relationship between stress S22 and indentation depth under different preload, the relationship between biaxial load amplitude and embedding depth, and the ratio of the preload loss caused by embedding to the total preload loss are revealed by finite element analysis.
The experiences of caring for disabled older adults in long-term: A qualitative study from the perspective of spousal caregivers
Authors: Yang Lingli , Wei Wei , Wu Yanni , Zhu Shunfang , Zeng Xiaoli , Wang Run , Zhang Mi , Lin Xiaolu , Zhou Chunlan
Published: January 2023

Objective

To explore the care experiences of spouses as long-term and primary caregivers for disabled older adults in China.

Methods

A descriptive phenomenological method was used in this study, as well as purposive and convenient sampling. Semi-structured interviews were conducted with 15 spousal caregivers in Guangdong, China, from March to December 2021. Interview audio-recordings were transcribed verbatim and data were analyzed using Colaizzi's phenomenological analysis method.

Results

We identified four themes from the data: spousal care motivation; sacrifices in caregiving; obstacles in caregiving; spousal caregivers’ positive experiences.

Conclusions

Spouses took responsibility for providing care for their disabled partners regardless of their willingness. They had positive experiences while providing care, but negative experiences were dominant, especially for spouses of severely disabled older adults. Spouses are always perfect in caregiving roles, although they may also need medical assistance. To prevent a decline in spousal caregivers’ quality of life and relieve their care burdens, health care providers should support them as soon as possible or offer formal care for disabled older adults. It is necessary to intervene considering disabled older adults and their spousal caregivers as a unit to empower their confidence in coping with life together.
Effects of training on the heart rate variability of competitive soccer players: A systematic review with meta-analysis
Authors: García-Ortega Dolores , Granero-Gallegos Antonio , Carrasco-Poyatos María
Published: January 2023

Heart rate variability (HRV) has become a popular method for monitoring readiness, recovery, and other training-derived parameters to optimize physical performance. This systematic review aimed to examine the impact of training interventions on HRV fluctuations in competitive soccer players. The EBSCO, Web of Sciences (WOS), and Cochrane databases were used for the search. After identifying 293 studies, 13 were included in a qualitative analysis and 6 in a quantitative analysis. Training had a small and nonsignificant effect on HRV in competitive soccer players (Effect Size (ES) = 0.143, Standard Error (SE) = .108, p = .186, 95% confidence interval (CI) [−0.69, 0.355]). Soccer-focused training resulted in higher HRV scores than combined training (Q(2) = 38.13, p = .05). Higher ES were found for frequency domain parameters ( p = .047; d = 0.059), night assessment ( p = .016; d = 0.453), and soccer-focused training ( p = .006; d = 0.366). HRV was also found to have a greater impact on females ( p = .027; d = 0.275) and/or professional soccer players ( p = .007; d = 0.302). Soccer training had a minimal and nonsignificant effect on HRV.
Bricks or clicks? Marketing dilemmas at Dawlance
Authors: Naz Baig Farah
Published: January 2023

Hasan Jameel, chief marketing officer at Dawlance, faced a strategic dilemma during the Covid pandemic. Founded in 1980, Dawlance was the leading home appliances company in Pakistan. Its products were distributed mainly through the dealer network to the end customers. The coronavirus pandemic led to lockdowns and disruption in the availability of goods. Jamil knew that this was the right time to go digital with their high-ticket appliances business. However, that move may create a backlash from the existing 1800 distributor spread all across the country. Covid was at its peak and he had to find a solution for the stagnant sales. Should he create an e-commerce platform or should he utilize the traffic of the biggest marketplace, Daraz, or should he use a combination of channels? His core target group included married couples in the urban and semi-urban centers. Would channel additions help him retain customers who were having issues during the pandemic? His team was unwilling to add the online channel option as they believed it would lead to a dealer backlash. He had 3 months and five million rupees to get the sales back on track.
Extremely dangerous hypopituitarism related long QT syndrome and transient ST-segment elevation: A case report
Authors: Zhang Jia , Zou Yingying , Chen Xiaoshu , Pan Jingye , Yu Haizhu , Wang Yi , Wu Yanran , Zou He
Published: January 2023

Acquired long QT syndrome caused by hypopituitarism and transient ST-segment elevation has not been reported in cardiac arrest patients. We report a case of extremely dangerous acquired long QT syndrome and transient ST-segment elevation. A 44-year-old Chinese woman with renal failure experienced sudden cardiac arrest in the haemodialysis room. Subsequent electrocardiogram showed QT prolongation and transient ST-segment elevation. This patient’s medical history, subsequent laboratory results and pituitary magnetic resonance imaging suggested hypopituitarism. Transient ST-segment elevation on the electrocardiogram was considered to be caused by repeated direct current shocks. The patient was diagnosed with acquired long QT syndrome and was not taking any antiarrhythmic drugs. Her corrected QT interval normalized after hormone replacement therapy. This case highlights the importance of the awareness of hypopituitarism; early identification and intervention can prevent the occurrence of this life-threatening arrhythmia. ST-segment elevation is not always due to acute myocardial infarction, and a variety of other causes, especially electrical cardioversion, should be considered.
From text to interaction: The digital advance directive method for advance directives
Authors: Biller Armin , Biller-Andorno Nikola
Published: January 2023

Advance directives allow people to specify individual treatment preferences in case of decision-making incapacity involving decisions of utmost importance. There are many tools that provide information on the topic, digital forms for structured data input, or platforms that support data storage and availability. Yet, there is no tool supporting the innermost process of an advance directive: decision making itself. To address this issue, we developed a visual-interactive, semi-quantitative method for generating digital advance directives (DiADs) that harnesses the potential of digitalization in healthcare. In this article, we describe the DiAD method and its app lined with the exemplary narrative of user Mr S. linking the theory to an exemplary use case. The DiAD method is intended to lower barriers and increase comfort in creating an advance directive by shifting the focus from heavily text-based processes to visual representation and interaction, that is, from text to reflection.
Factors Affecting the Academic Tripping at University of Tabuk Using Logistic Regression
Authors: Yagoub Rahmtalla Yousif , Eledum Hussein Yousif , Yassin Atif Ali
Published: January 2023

The main objective of this article is to use the logistic regression model as one of the generalized linear models to determine some factors that influence academic tripping at the University of Tabuk. In this case, student status (tripped, non-tripped) is considered as a binary variable. The data of this article were collected using a survey based on a questionnaire. The results showed that the most important factors affecting student’s academic tripping have focused on the items of educational & academic, and family & economic factors, namely (a) the current speciality does not meet student’s aspiration, (b) it is difficult for the student to understand and accommodate some lectures, (c) it is difficult for the student to reconcile the academic load with the offered courses, (d) participation in extra-curricular activities, (e) difference between university and secondary schools systems, and (f) student does not receive a college bursary regularly.
Hear Me Out! This Is My Idea: Transformational Leadership, Proactive Personality and Relational Identification
Authors: Adhyke Yuzy Prila , Eliyana Anis , Sridadi Ahmad Rizki , Septiarini Dina Fitriasia , Anwar Aisha
Published: January 2023

This study proposes that there is relationship between transformational leadership and employee’s voice as well as relational identification as a mediation and proactive personality as a moderator. Structural Equation Modeling was used to analyze data gathered from employees at the Ministry of Law and Human Rights through questionnaires. The findings revealed that transformational leadership has a significant effect on employee’s voice and relational identification; relational identification mediates the relation between transformational leadership and employee voice behavior, and proactive personality will weaken the transformational effect on employee’s voice behavior. This study enriches empirical studies that employee’s voice can represent the opinions and ideas of employees with the presence of relational identification, proactive personality, and transformational leadership in the organization. Furthermore, transformational leadership can build relational identification that is strengthened by a proactive personality so that employees are happy to convey their voices.
Triple Method Approach to Development of a Genre-Based Approach to Teaching ESL/EFL Writing: A Systematic Literature Review by Bibliometric, Content, and Scientometric Analyses
Authors: Zhai Xiuwen , Razali Abu Bakar
Published: January 2023

In the last 19 years (2003–2021), research on genre-based approaches (GBAs) to writing pedagogy has been accumulating in the fields of English as a second language (ESL) and English as a foreign language (EFL). This review mapped existing literature to identify research trends and provide a research agenda for future GBAs. This study employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and identified 52 published articles and 2 unpublished doctoral theses via a structured keyword search on Web of Science, Scopus, ERIC, Google Scholar, and ProQuest in the fields of teaching English to speakers of other languages, language learning, and education. The results show that GBA is now widely used in teaching English academic writing to ESL/EFL tertiary/graduate students. The main research findings include: (1) the top five countries in the number of paper publications are China (i.e., five), the United States (i.e., five), Japan (e.g., 4), Thailand (e.g., four), and Sweden (e.g., four); (2) the top four authors in the number of paper publications are Hyland (i.e., two), Lu (i.e., two), Negretti (i.e., two), and Pineh (i.e., two); and (3) the top three most strengthen keywords are writing pedagogy, genre-based approach, and English for academic purpose. This study also discusses the theoretical and practical implications.
Resilience, Social Support, and Health in Emerging Adults With and Without Chronic Health Conditions
Authors: Lynch Milder Mary K. , Bazier Ashley , Ward Sydney , Rand Kevin L. , Hirsh Adam T.
Published: January 2023

Resilience and social support are important for emerging adults and especially those with chronic health conditions (CHC). We examined associations among resilience, social support, and health in those with and without a CHC. 132 emerging adults with a CHC and matched healthy participants completed questionnaires. Two-group, measuredvariable path analysis and mediational models were conducted. Those with a CHC had poorer resilience and health but equivalent social support. Resilience significantly predicted general health and emotional well-being. Resilience mediated the relationships between coping and health for healthy participants and between coping and emotional wellbeing in those with a CHC. Satisfaction with social support was significantly correlated with health, mediating the influence of network size on emotional well-being for those without a CHC and both physical functioning and emotional well-being for healthy participants. These results indicate the importance of resilience and social support for emerging adults, especially those with a CHC.
Understanding the Appropriate and Beneficial Use of Before and After Photos in Breast Surgery: A North American Survey
Authors: Datta Shaishav , R. Valiquette Chantal , Somogyi Ron
Published: January 2023

Introduction: Before and after photographs (BAPs) in breast surgery have been identified as important components of the informed consent process. Currently, there is limited consensus on the contents and presentation of BAPs. This study collected the opinions of prior and prospective patients on this topic. Methods: A survey, based on criteria identified by our previous nominal group technique (NGT) study, was designed to obtain patient perspectives on BAPs in breast surgery. Amazon Mechanical Turk, a validated crowd-sourcing tool, was used to identify and survey a group of 72 participants who indicated that they had undergone or were planning to undergo breast surgery. Likert items were analyzed using either chi-squared or Fisher's exact test. Results: Most respondents were cis-gendered-women (89%), Caucasian (83%), and between 31 and 41 years old (38%). Respondents agreed that BAPs are important to the consent process, for enabling patient-centered care, and should be presented in standardized sets. BAPs should be more accessible through different platforms, display multiple time points to show the healing process, and have multiple views including close-ups of scars. Photos should be unaltered except for de-identification, and have more diversity with regard to patient gender, age, skin color, and body mass index. These results align with results from our NGT study. Conclusion: Through this study we have identified many criteria that BAPs should meet according to prior and prospective breast surgery patients. Surgeons should think critically about how they present BAPs during the consent process to ensure effective patient-centered care.
Construing the Relationship Between Entrepreneurial Adversity and Mental Well-being of Small Business Owners During COVID-19 Outbreak: The Mediating Role of Entrepreneurial Resilience
Authors: Singh Shruti , Chakraborty Anindita
Published: January 2023

The purpose of this study was to look at small business owners’ entrepreneurial resilience and mental well-being during adversity. This paper tries to gauge the effect of the COVID-19 pandemic on an entrepreneur’s mental wellness and how being resilient in their approach to handling uncertainties mediates and positively envisages their mental wellness. The quantitative approach was utilized to collect data and achieve the specified goal. The information was gathered from 159 small business owners in Varanasi, India. The partial least squares method was used to analyze the collected data. Future research should look for more accurate ways to measure resilience as well as personal traits that could be used to further analyze the person–entrepreneurial context fit. In order to improve the generalizability of the study’s findings, researchers can also consider perceived adversity and resilience as mediating factors, in addition to the actual adversity and resilience assessed in this study.
The Landscape of Digital Natives Research: A Bibliometric and Science Mapping Analysis
Authors: Dastane Omkar , Haba Herman Fassou
Published: January 2023

This article provides a panoramic view of the research undertaken so far in the field of digital natives to highlight important trends, examine the intellectual structure and provide recommendations for future research. The study uses 983 publications from the Scopus database to analyse the productivity, impact and research performance of nations, journals, authors and institutions using indicators such as impact factor, h-index and citation counts. This review study uses bibliometric and science mapping analysis to assess the most recent developments and trends in ‘digital native’ research. VOSviewer is used to conduct keyword network analysis, co-authorship analysis and reference co-citation analysis, followed by SciMAT analysis to provide an evolution map and a cluster of themes. The analysis identified key contributors to the field, high-impact papers and geographic areas where field research is concentrated. The main research gaps were then identified, indicating future research avenues. The findings of this study will provide fresh higher-level insights into the developing field of digital native research for educators, computing executives, business managers and research scholars. Such information would be useful in establishing digital native recruitment tactics by the respective industry. The research will also aid in the development of policies for digital natives.
Power and Politics: A Case of Hotel Amada
Authors: Baber Ruturaj , Baber Prerana , Sanyal Alka
Published: January 2023

Organizational politics and conflicts thrive at all levels of the organization. It is an unavoidable fact of working life. The present case discusses about Ashish had a lot of ambitions ever since he was employed with the organization. However, during the first three months of his engagement with the organization, something caused him to decide that he decided not to continue working there for another day. After completing his degree, Ashish was hired as a sous chef in a well-known hotel in Gwalior, India (M.P). Ashish was unable to carry out his responsibilities competently simply because he was not provided with an appropriate platform. His immediate boss does not provide him with an opportunity to demonstrate his abilities. The salary that had been promised had also not been delivered. Even the tasks that were assigned were not according to his capability. He was dissatisfied with the conditions of his work environment. He attempted to rectify the situation but was ultimately unsuccessful. Along with this, he also had heated disagreements with his immediate supervisor, Satish. The level of stress was soaring with each passing day. He became even more resentful as a result, and he began to consider quitting his job.
Prolonged Thrombocytopenia in a Case of MIS-C in a Vaccinated Child
Authors: Demharter Neera Shah , Rao Pooja , Scalzi Lisabeth V. , Ericson Jessica E. , Clarke Sheila
Published: January 2023

Multisystem inflammatory syndrome in children (MIS-C) has been extensively described in patients following severe acute respiratory syndrome coronavirus 2 infection. There are now questions about what MIS-C may look like in vaccinated children. Multisystem inflammatory syndrome in children has many clinical and laboratory features in common with other inflammatory disorders including Kawasaki disease and toxic shock syndrome. Rheumatologic conditions can present with similar musculoskeletal complaints and elevated inflammatory markers. Laboratory markers and clinical symptoms of MIS-C usually improve once therapy is begun. We describe a child with persistent thrombocytopenia as an example of variable presentation of MIS-C in vaccinated children. This case report discusses an atypical progression of MIS-C in a vaccinated child with a known prior positive COVID-19 polymerase chain reaction (PCR) test. She presented with nonspecific abdominal pain and fever and was found to have elevated inflammatory markers, lymphopenia, and thrombocytopenia. Intravenous immunoglobulin and steroid treatment failed to induce rapid recovery in her clinical condition or thrombocytopenia. Rheumatologic, hematologic, oncologic, and infectious causes were considered and worked up due to the uncertainty of her case and persistence of pancytopenia but ultimately were ruled out with extensive testing and monitoring. It was key to include a broad differential including viral-induced bone marrow suppression, idiopathic thrombocytopenic purpura, secondary hemophagocytic lymphohistiocytosis, systemic juvenile idiopathic arthritis, and malignancy. The spectrum of MIS-C and response to treatment continues to evolve, and prior vaccination in this child’s case complicated the clinical picture further. Additional evaluation of MIS-C in vaccinated cases will permit characterization of the range of MIS-C presentation and response to standard therapy.
“It’s Still in the Test Tube and Finding out How the Experiment Ends… ”. A Qualitative Study on Health and Aging in Older Gay Males Living with HIV in England
Authors: Licchelli Stefano , King Andrew , Smith Kimberley J.
Published: January 2023

This paper highlights experiences and perceptions of older gay males living with Human Immunodeficiency Virus (HIV) in relation to age, sexual orientation, HIV status and how they perceive health. Participants were gay males aged 50 and over living in England, diagnosed with HIV for longer than 2 years. In total, 19 interviews were conducted between March 2020 and March 2021. Data were analysed using thematic analysis. Three major themes were generated: 1.) Health as holistic and as a balance; 2.) The impact of HIV on people’s lives; 3.) The Intersectionality of stigma: a lifetime of discrimination. Participants highlighted the changing nature of the concept of health through their lifespan while the intersectionality of stigma in different contexts is examined considering the personal journey of living with HIV. The implications of health as a complex concept and intersectional stigma on the planning and delivering of care in this population are discussed.
Capsular Warning Syndrome Leading to Acute Ischemic Stroke in a Pediatric Patient Secondary to Varicella Zoster Virus
Authors: Shen Min Ye , Heshmati Arezou
Published: January 2023

We report the case of a 3-year-old boy who presented with recurrent stereotyped transient episodes of left sided weakness consistent with capsular warning syndrome (CWS) which eventually progressed to acute ischemic stroke (AIS). He received thrombolytic therapy with tissue plasminogen activator. Workup was notable for positive CSF varicella (VZV) PCR, and positive CSF and serum VZV IgG and negative IgM. On further history, he was unvaccinated and had a rash consistent with VZV 5 months prior to presentation. This case highlights the importance of recognizing CWS given the increased risk of progression to AIS. In addition, it emphasizes the importance of considering VZV vasculopathy in pediatric AIS and inquiring about infectious history and immunization status despite high rates of vaccination in the United States.
Employee Relations Today and Its Conundrums
Authors: Kappagantula Padmakar
Published: January 2023

The world has moved on from industrial relations to employee relations. Enterprises have grown in complexity with technology outpacing people. People in enterprises today are multi-generational and have grown equally complex as well as facing bewildering choices before them. Mere engagement tools stopped giving effective results. How to reach into their inner selves help them understand themselves and their choices to act upon is the role of line and HR today.
Changing Paradigm of Employee Relations in India after Independence
Authors: Kumar Jayant
Published: January 2023

The article critically analyses evolution of industrial relations (IR) into employee relations (ER) with changing industrial landscape and workforce dynamics. Role of various stakeholders including employers, leadership, employees and legislations in evolution of employee relations has been explored. It covers influence of critical factors shaping IR and ER in post-independence India from its transition from an agrarian economy to industrial and emergence of a dominant service economy. Role of leadership at different levels and response strategy of organisations have been changing over period with clear patterns. Effect of economic liberalisation and new economic policy on management of employee relations has also been explored. Based on trends of the past, forecasting has been made regarding form and shape of ER in near future. In summary, this article attempts to analyse historical development of IR and ER, Trade Unions, Collectivism in India and identify important factors that led to its current state of existence.
Possible Gender Differences in Classical Music, Flamenco and Fado
Authors: Garcia-Falgueras Alicia
Published: January 2023

Music is an art form and cultural activity whose language, the sounds and silences, is organized in time with logic and sensitivity. Music as a whole is the result of an ancestral nonverbal and international mode of human expression and communication. The primitive and former mother-child bonding might be highly influenced and modulated by the music and singing with their babies. Musicality and music imply two different sides of the same coin, where the former is based on the human capacity to produce the latter. Some theories about evolution suggest music might have an adaptive advantage for humans in society. Historical examples of different styles in music point out that if any allusion or reminder about gender in music might happen most probably occurs in folk non always written pagan or secular music with lyrics or voice. This genre of music usually tells about traditional gender differences in jobs, habits, lifestyles, etc., and has a clear preference for male musicians, while on the contrary, classical music usually does not have a clear gender difference in meaning, and instruments are played by both. In this text, I explore and empirically describe, neuroanatomically or functionally, some examples of different genres of music and brain differences, related to music and dance. Three different genres of music (Classical music, Fado and Flamenco) are explored in an attempt to elucidate some reasons for possible gender differences.
Osteochondral Allograft Transplantation
Authors: Belk John W. , Bravman Jonathan T. , Frank Rachel M. , Dragoo Jason L. , McCarty Eric C.
Published: January 2023

Background:

Articular cartilage lesions are a significant cause of morbidity and impaired knee function, and attempts to surgically repair damaged cartilage have failed to reliably reproduce native cartilage. Thus, osteochondral allograft transplantation is an effective one-step procedure to repair large cartilage defects.

Indications:

Osteochondral allograft transplantation is indicated for young active patients with large focal defects, those with a history of previous cartilage repair, and those with cartilage-related degenerative disorders such as osteonecrosis, osteochondritis dissecans, and/or post-traumatic osteochondral defects.

Technique Description:

In short, after the focal chondral defect is identified, a socket is created with specific dimensions in depth and diameter. The donor cartilage is then secured in a graft station, and a sizing guide is placed through a bushing to confirm the allograft harvest location. Using stabilization from the graft station arm, a coring reamer is then advanced through the donor cartilage, and a saw is used to allow for easy removal of the graft from the donor condyle. The plug is then fashioned to fit the exact dimensions of the socket created earlier in the procedure. A cut on the donor plug is made to fashion the plug to the appropriate depth. A rongeur is used to make the plug more bullet shaped at the end to allow the plug to enter the socket more easily. Small holes are then drilled into the base of the socket to help promote incorporation of the plug into the socket during the healing process. After the socket is irrigated, the plug is then placed into the socket, and a tamp is used to gently tap the cartilage until it is flush with the surrounding surface.

Results:

After an appropriate rehabilitation protocol is followed for up to 10 months postoperatively, osteochondral allograft transplantation allows for near-to-complete restoration of patient functionality and strength, with return to full activity possible within 1 year.

Conclusion:

Acute repair of large focal chondral defects is effective in restoring knee strength and functionality and is associated with high patient satisfaction. The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. If the individual may be identifiable, the author(s) has included a statement of release or other written form of approval from the patient(s) with this submission for publication.
Equality pledges: A novel approach to embedding EDI and promoting positive culture change in a UK university
Authors: Watson Helen R , Wisdom Hannah , Michael Caryn , Marshall Nathan , Neve Hilary
Published: January 2023

Higher education (HE) in the UK continues to prioritise equality (or equity), diversity and inclusion (EDI), but stark inequalities still exist, and non-inclusive cultures persist. We have created the Equality Pledge (EP) scheme which empowers HE staff to contribute to positive culture change by making a personal pledge to improve some aspect of EDI in their working lives. We encouraged staff to each set a manageable pledge, either individually or as a team, so as not to increase already high workloads. Staff recorded their pledges on an online form, and six-monthly updates were requested to capture impact, progress and feedback on the initiative. We recorded over 260 pledges from staff in the Faculty, aiming to tackle issues around teaching and learning, working practices, self-development, admissions, marketing and other issues. Over 100 staff have now recorded progress updates, which reveal significant impact. The EPs have also led to a significant increase in dialogue around EDI and, we believe, the beginning of a positive shift in culture. Within our own university, other faculties are now beginning to roll-out the EP. This initiative has relevance across HE and other sectors. It is a practical intervention to facilitate positive culture change.
Posttransplantation cyclophosphamide expands functional myeloid-derived suppressor cells and indirectly influences Tregs
Authors: Fletcher Rochelle E. , Nunes Natalia S. , Patterson Michael T. , Vinod Natasha , Khan Shanzay M. , Mendu Suresh K. , Li Xianghong , de Paula Pohl Alessandra , Wachsmuth Lucas P. , Choo-Wosoba Hyoyoung , Eckhaus Michael A. , Venzon David J. , Kanakry Christopher G.
Published: January 2023

Posttransplantation cyclophosphamide (PTCy), given on days +3 and +4, reduces graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT), but its immunologic underpinnings are not fully understood. In a T-cell–replete, major histocompatibility complex-haploidentical murine HCT model (B6C3F1→B6D2F1), we previously showed that PTCy rapidly induces suppressive mechanisms sufficient to prevent GVHD induction by non-PTCy–exposed donor splenocytes infused on day +5. Here, in PTCy-treated mice, we found that depleting Foxp3+ regulatory T cells (Tregs) in the initial graft but not the day +5 splenocytes did not worsen GVHD, yet depleting Tregs in both cellular compartments led to fatal GVHD induced by the day +5 splenocytes. Hence, Tregs were necessary to control GVHD induced by new donor cells, but PTCy’s impact on Tregs appeared to be indirect. Therefore, we hypothesized that myeloid-derived suppressor cells (MDSCs) play a complementary role. Functionally suppressive granulocytic and monocytic MDSCs were increased in percentages in PTCy-treated mice, and MDSC percentages were increased after administering PTCy to patients undergoing HLA-haploidentical HCT. PTCy increased colony-stimulating factors critical for MDSC development and rapidly promoted the generation of MDSCs from bone marrow precursors. MDSC reduction via anti-Gr1 treatment in murine HCT did not worsen histopathologic GVHD but resulted in decreased Tregs and inferior survival. The clinical implications of these findings, including the potential impact of expanded MDSCs after PTCy on engraftment and cytokine release syndrome, remain to be elucidated. Moreover, the indirect effect that PTCy has on Tregs, which in turn play a necessary role in GVHD prevention by initially transplanted or subsequently infused T cells, requires further investigation.
A hybrid algorithm for clinical decision support in precision medicine based on machine learning
Authors: Zhang Zicheng , Lin Xinyue , Wu Shanshan
Published: January 2023

Purpose

The objective of the manuscript is to propose a hybrid algorithm combining the improved BM25 algorithm, k-means clustering, and BioBert model to better determine biomedical articles utilizing the PubMed database so, the number of retrieved biomedical articles whose content contains much similar information regarding a query of a specific disease could grow larger.

Design/methodology/approach

In the paper, a two-stage information retrieval method is proposed to conduct an improved Text-Rank algorithm. The first stage consists of employing the improved BM25 algorithm to assign scores to biomedical articles in the database and identify the 1000 publications with the highest scores. The second stage is composed of employing a method called a cluster-based abstract extraction to reduce the number of article abstracts to match the input constraints of the BioBert model, and then the BioBert-based document similarity matching method is utilized to obtain the most similar search outcomes between the document and the retrieved morphemes. To realize reproducibility, the written code is made available onhttps://github.com/zzc1991/TREC_Precision_Medicine_Track.

Findings

The experimental study is conducted based on the data sets of TREC2017 and TREC2018 to train the proposed model and the data of TREC2019 is used as a validation set confirming the effectiveness and practicability of the proposed algorithm that would be implemented for clinical decision support in precision medicine with a generalizability feature.

Originality/value

This research integrates multiple machine learning and text processing methods to devise a hybrid method applicable to domains of specific medical literature retrieval. The proposed algorithm provides a 3% increase of P@10 than that of the state-of-the-art algorithm in TREC 2019.
Transcriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii)
Authors: Yang Shiyong , Li Datian , Feng Langkun , Zhang Chaoyang , Xi Dandan , Liu Hongli , Yan Chaozhan , Xu Zihan , Zhang Yujie , Li Yunkun , Yan Taiming , He Zhi , Wu Jiayun , Gong Quan , Du Jun , Huang Xiaoli , Du Xiaogang
Published: January 2023

Background

Maintaining osmotic equilibrium plays an important role in the survival of cold-water fishes. Heat stress has been proven to reduce the activity of Na+/K+-ATPase in the gill tissue, leading to destruction of the osmotic equilibrium. However, the mechanism of megatemperature affecting gill osmoregulation has not been fully elucidated.

Results

In this study, Siberian sturgeon (Acipenser baerii) was used to analyze histopathological change, plasma ion level, and transcriptome of gill tissue subjected to 20℃, 24℃and 28℃. The results showed that ROS level and damage were increased in gill tissue with the increasing of heat stress temperature. Plasma Cl− level at 28℃ was distinctly lower than that at 20℃ and 24℃, while no significant difference was found in Na+ and K+ ion levels among different groups. Transcriptome analysis displayed that osmoregulation-, DNA-repair- and apoptosis-related terms or pathways were enriched in GO and KEGG analysis. Moreover, 194 osmoregulation-related genes were identified. Amongst, the expression of genes limiting ion outflow, occluding (OCLN), and ion absorption, solute carrier family 4, member 2 (AE2) solute carrier family 9, member 3 (NHE3) chloride channel 2 (CLC-2) were increased, while Na+/K+-ATPase alpha (NKA-a) expression was decreased after heat stress.

Conclusions

This study reveals for the first time that the effect of heat stress on damage and osmotic regulation in gill tissue of cold-water fishes. Heat stress increases the permeability of fish’s gill tissue, and induces the gill tissue to keep ion balance through active ion absorption and passive ion outflow. Our study will contribute to research of global-warming-caused effects on cold-water fishes.