bluuebunny/crossref_metadata_2025 huggingface dataset:
Meditation mobile app developed for cancer patients and survivors: A feasibility study (Preprint)
Authors: Huberty Jennifer , Bhuiyan Nishat , Puzia Megan , Joeman Lynda , Larkey Linda , Mesa Ruben
Published: May 2022

BACKGROUND

To address the unmet need for a commercial cancer-specific meditation app, we leveraged a long-standing partnership with a consumer-based app (i.e., Calm) to develop the first commercial meditation app prototype adapted specifically for cancer patients’ needs. Input was obtained at both the individual user and clinic level (i.e., cancer patients/survivors and healthcare providers).

OBJECTIVE

The purpose of this study was to determine the feasibility of the cancer-specific meditation app prototype

METHODS

Cancer patients and survivors who were recruited and enrolled into the feasibility trial were asked to use the prototype daily (≥70 minutes/week) for four weeks. Participants completed online weekly questionnaires, a final post-study questionnaire, and were asked to participate in a virtual post-study interview. Questionnaires and interviews covered the following feasibility categories: acceptability, demand, practicality, and adaptation.

RESULTS

A total of 36 cancer patients and survivors completed the baseline questionnaire, 18 completed the final questionnaire, and six completed the optional interviews. Weekly and post-study questionnaires indicated high overall enjoyment, ease of use, and satisfaction with the app content, aesthetics, and graphics. Objective usage data indicated that the average total app usage rate was 143.41 minutes/week (SD=180.57). Interviews (N=6) revealed positive and mixed responses to the app prototype and informative differences related to preferences for narrators, emotional content, meditation teaching, and an overall appreciation for the variety of options.

CONCLUSIONS

The most likely candidate for moving from cancer-specific meditation apps to, eventually, dissemination, are through partnering with industry where a name recognition and market distribution is already established (even showing a base of users from the targeted cancer population).This study established the feasibility of a cancer-specific mobile meditation app prototype among cancer patients and survivors leveraging a commercially available app. Quantitative and qualitative data demonstrated acceptability, demand, practicality, and adaptation of the prototype. Participant’s suggested improvements will be considered in the final app design prior to testing the app for its efficacy in a future study.
The Potential Digital-Based Nursing Intervention to Improve Mental Health in Adolescents during COVID-19 Pandemic: A Scoping Review (Preprint)
Authors: Yosep Iyus , Hikmat Rohman , Mardhiyah Ai
Published: May 2022

BACKGROUND

COVID-19 pandemic can cause problems in adolescent mental health such as anxiety, depression, and stress. This is because the distance barrier becomes an obstacle in handling mental health in adolescents. The use of technology has the potential to deal with mental health problems.

OBJECTIVE

The purpose of this study was to describe the digital-based nursing interventions in dealing with mental health problems in adolescents during the COVID-19 pandemic.

METHODS

This study used the Scoping Review method. Literature review via CINAHL, PubMed, and ProQuest databases. The keywords are adolescence, mental health, digital, application, nursing intervention in English. The criteria for articles in this study were full-text articles, the sample of adolescents, intervention, articles are original research, full text, and time setting 2018-2022.

RESULTS

Found 11 articles discussing digital nursing interventions to deal with mental health problems in adolescents. There are 2 types of intervention, namely mobile-based intervention, and web-based intervention. The two interventions can be combined to become a method of providing digital nursing interventions that are effective and can reach the entire community.

CONCLUSIONS

Digital-based nursing interventions consisting of mobile-based intervention and web-based intervention can improve adolescent mental health by reducing stress, anxiety, depression, and increasing resilience, well-being, and self-efficacy.
How do people interpret health information in the context of an emerging infectious disease? Digital focus group exploring perceptions of novel health information during the first wave of COVID-19 restrictions in Singapore (Preprint)
Authors: Tan Rayner Kay Jin , Lim Jane Mingjie , Neo Pearlyn Hui Min , Ong Suan Ee
Published: May 2022

BACKGROUND

Misinformation related to the COVID-19 pandemic has accelerated global public concern and panic. The glut of information, or ‘infodemic’, has caused concern for the authorities due to its negative impacts on COVID-19 prevention and control, spurring calls for a greater scholarly focus on health literacy during the pandemic. Nevertheless, few studies have sought to qualitatively examine how individuals interpreted and assimilated health information at the initial wave of COVID-19 restrictions.

OBJECTIVE

We developed this qualitative study adopting chat-based focus group discussions to investigate how individuals interpreted COVID-19 health information during the first wave of COVID-19 restrictions.

METHODS

We conducted a qualitative study in Singapore to investigate how individuals perceive and interpret information that they receive on COVID-19. Data were generated through online focus group discussions conducted on the mobile messaging smartphone app, WhatsApp. From 28 March to 13 April 2020, we held eight WhatsApp-based focus groups (n=60) with participants stratified by age groups, namely 21 to 30 years, 31 to 40 years, 41 to 50 years, and 51 years and above. Data were thematically analysed.

RESULTS

A total of four types of COVID-19 health information were generated from analysis; labelled as formal health information, informal health information, suspicious health information, and fake health information. How participants interpreted these categories of information depended largely on the perceived trustworthiness of the information source, as well as perceived veracity of information. Both factors were instrumental to determining individuals’ perceptions and their subsequent treatment and assimilation of COVID-19-related information.

CONCLUSIONS

Both perceived trustworthiness of the information source and perceived veracity of information were instrumental concepts in determining one’s perception, and thus subsequent treatment and assimilation of such information for one’s knowledge of COVID-19, or the onward propagation to their social networks. These findings have implications for how policymakers and health authorities communicate with the public and deal with fake health information in the context of COVID-19.
Vi phân suy rộng của hàm giá trị tối ưu trong điều khiển tối ưu có tham số cho phương trình đạo hàm riêng elliptic
Authors: Nguyễn Thành Quí , Đào Duy Phúc
Published: May 2022

Công trình này thuộc hướng nghiên cứu sự ổn định vi phân của các bài toán điều khiển tối ưu có tham số cho phương trình vi phân đạo hàm riêng elliptic nửa tuyến tính. Bài báo thu được các kết quả mới theo hướng nghiên cứu này bao gồm việc thiết lập các công thức vi phân của ánh xạ nghiệm của phương trình vi phân đạo hàm riêng elliptic nửa tuyến tính và hàm mục tiêu của bài toán điều khiển tối ưu có tham số. Qua đó, công thức tính toán dưới vi phân chính quy (dưới vi phân Fréchet) được xây dựng cho hàm giá trị tối ưu của bài toán điều khiển tối ưu có tham số đang xét.
Phân tích mô tả định lượng và phân tích thành phần chính đối với đặc điểm cảm quan của củ cải và dưa leo muối chua trong môi trường cám gạo
Authors: Nguyễn Minh Thủy , Lê Thị Tuyết Như , Hồ Thị Cẩm Nhi , Nguyễn Thị Huỳnh Nhi , Trần Chí Bên , Hồ Thị Ngân Hà , Ngô Văn Tài
Published: May 2022

Mục tiêu của nghiên cứu là sử dụng phương pháp phân tích mô tả định lượng (QDA) để đánh giá các thuộc tính cảm quan của sản phẩm củ cải trắng và dưa leo muối chua trong môi trường cám gạo. Ba mươi cảm quan viên được lựa chọn và đào tạo để đánh giá các thuộc tính màu sắc, hình dạng, kết cấu, hương vị và khả năng chấp nhận tổng thể của hai sản phẩm. Phương pháp phân tích thành phần chính (PCA) được sử dụng để xác định hai thành phần chính quan trọng chiếm lần lượt là 88,75% và 81,40% phương sai. Tỷ lệ phối chế cám gạo: nước: muối là 49: 48: 3 (mẫu củ cải F3), 49: 48: 3 (mẫu dưa leo M3) và 45: 52: 3 (mẫu dưa leo M4) cho giá trị cảm quan cao và được yêu thích nhất. Kết quả thu nhận đã chứng minh tính hữu ích của phương pháp phân tích mô tả định lượng trong việc xác định và đo lường các đặc tính cảm quan của sản phẩm củ cải trắng và dưa leo muối chua trong môi trường cám gạo.
Đánh giá chất lượng nước và thải lượng từ ao nuôi tôm thẻ chân trắng (Litopenaeus vannamei) thâm canh ở tỉnh Sóc Trăng
Authors: Ngô Thụy Diễm Trang , Trần Đình Duy , Trịnh Phước Toàn , Nguyễn Hải Thanh , Nguyễn Thạch San , Trần Sỹ Nam
Published: May 2022

Nghiên cứu được thực hiện nhằm xác định môi trường nước ao nuôi và thải lượng từ ao tôm thẻ chân trắng (Litopenaeus vannamei) nuôi thâm canh với mật độ nuôi khác nhau ở tỉnh Sóc Trăng. Các ao nuôi có độ sâu trung bình 1,4 m và diện tích mặt nước 3.100-4.700 m2. Nhóm ao nuôi mật độ thấp là 80-90 con/m2 và nhóm ao nuôi mật độ cao là 130-140 con/m2. Mẫu nước được thu và đánh giá từ đầu vụ đến cuối vụ nuôi với tần suất 2 tuần/1 lần. Chất lượng nước trong các đợt thu mẫu được người nuôi duy trì ở ngưỡng thích hợp cho tôm thẻ chân trắng sinh trưởng và nằm trong quy định của QCVN 02-19:2014/BNNPTNT, ngoại trừ pH và độ kiềm trong ao nuôi mật độ cao. Tuy nhiên, để sản xuất 1 tấn tôm cần có 6.644-8.289 m3 nước thải, 27,9-29,9 m3 nước xi phông, 145-179 kg COD, 12,5-16,3 kg P và 57,6-77,5 kg TKN thải vào môi trường qua quá trình thay nước và xi phông. Vì vậy, việc quản lý và xử lý nước thay ra và nước xi phông từ các ao nuôi tôm thâm canh là rất cần thiết để giảm thiểu lượng chất thải đưa vào môi trường xung quanh khu vực nuôi.
Nghiên cứu hoạt tính gây độc của cao chiết ethanol từ trâm ổi (Lantana camara L.) trên ruồi giấm (Drosophila melanogaster)
Authors: Tăng Huyền Cơ , Trần Thanh Mến
Published: May 2022

Nghiên cứu này sử dụng ruồi giấm Drosophila melanogaster để đánh giá độc tính của cao chiết ethanol trâm ổi. Kết quả định tính cho thấy trâm ổi có sự hiện diện alkaloids, flavonoids, saponins, phenolics, tanins, terpenoids, cardiac glycosides và steroids-triterpenoids. Polyphenols và flavonoids tổng được xác định lần lượt là 123±2,30 mg GAE/g và 309±2,17 mg QE/g cao chiết. Cao chiết trâm ổi có khả năng gây độc cho ruồi giấm ở các nồng độ khác nhau. Ở nồng độ 250 mg/mL, trâm ổi gây chết 84,4±8,39% và nồng độ gây chết 50% (LD50) được xác định là 140 mg/mL. Ở nồng độ 20 mg/mL, trâm ổi ảnh hưởng đến sự sinh trưởng và phát triển của ruồi giấm thể hiện qua số nhộng hình thành thấp hơn so với đối chứng, tỉ lệ chết ở giai đoạn nhộng 55,9±2,09%, khả năng tích trữ năng lượng như carbohydrate, lipid và protein giảm. Nghiên cứu còn ghi nhận trâm ổi có khả năng ức chế hoạt tính của các enzyme thuộc nhóm esterase và phosphatase. Từ đó cho thấy trâm ổi là thực vật có khả năng tổng hợp các hợp chất thứ cấp gây độc cho ruồi giấm.
Tổng quan nghiên cứu về nấm rễ nội cộng sinh ở Việt Nam
Authors: Trần Hoàng Siêu
Published: May 2022

Canh tác nông nghiệp bền vững đặt ra những thách thức lớn trong việc tiếp cận những ứng dụng sinh học có tính hiệu quả cao và thân thiện với môi trường. Nấm rễ nội cộng sinh (AMF) hình thành mối quan hệ với hầu hết các loài thực vật cạn và cây lúa được trồng trong điều kiện ngập nước đóng góp nhiều ý nghĩa quan trọng đối với canh tác nông nghiệp và xử lý môi trường sinh thái. Bài tổng quan về lĩnh vực nghiên cứu nấm rễ nội cộng sinh này được thực hiện nhằm tổng hợp lại tình hình nghiên cứu nấm rễ nội cộng sinh tại Việt Nam hiện nay, từ đó đề xuất các hướng nghiên cứu mới nhằm khám phá tiềm năng của AMF giúp hỗ trợ cây trồng về hấp thụ nước và dinh dưỡng khoáng trong đất cũng như hạn chế kim loại nặng, tăng cường sức chống chịu của cây trồng trong các điều kiện bất lợi của môi trường (nhiệt độ cao, nhiễm mặn, khô hạn, nghèo dinh dưỡng) thông qua đó tăng năng suất cây trồng. Cuối cùng, những tác động tích cực của AMF còn đặt ra cơ hội mới trong việc sản xuất phân bón sinh học nhằm giảm thiểu sự phụ thuộc vào phân bón hóa học trong trồng trọt.
Association of Phosphate-Containing versus Phosphate-Free Solutions on Ventilator Days in Patients Requiring Continuous Kidney Replacement Therapy
Authors: Thompson Bastin Melissa L. , Stromberg Arnold J. , Nerusu Sethabhisha N. , Liu Lucas J. , Mayer Kirby P. , Liu Kathleen D. , Bagshaw Sean M. , Wald Ron , Morris Peter E. , Neyra Javier A.
Published: May 2022

Background and objectives

Hypophosphatemia is commonly observed in patients receiving continuous KRT. Patients who develop hypophosphatemia may be at risk of respiratory and neuromuscular dysfunction and therefore subject to prolongation of ventilator support. We evaluated the association of phosphate-containing versus phosphate-free continuous KRT solutions with ventilator dependence in critically ill patients receiving continuous KRT.

Design, setting, participants, & measurements

Our study was a single-center, retrospective, pre-post cohort study of adult patients receiving continuous KRT and mechanical ventilation during their intensive care unit stay. Zero-inflated negative binomial regression with and without propensity score matching was used to model our primary outcome: ventilator-free days at 28 days. Intensive care unit and hospital lengths of stay as well as hospital mortality were analyzed with a t test or a chi-squared test, as appropriate.

Results

We identified 992 eligible patients, of whom 649 (65%) received phosphate-containing solutions and 343 (35%) received phosphate-free solutions. In multivariable models, patients receiving phosphate-containing continuous KRT solutions had 12% (95% confidence interval, 0.17 to 0.47) more ventilator-free days at 28 days. Patients exposed to phosphate-containing versus phosphate-free solutions had 17% (95% confidence interval, −0.08 to −0.30) fewer days in the intensive care unit and 20% (95% confidence interval, − 0.12 to −0.32) fewer days in the hospital. Concordant results were observed for ventilator-free days at 28 days in the propensity score matched analysis. There was no difference in hospital mortality between the groups.

Conclusions

The use of phosphate-containing versus phosphate-free continuous KRT solutions was independently associated with fewer ventilator days and shorter stay in the intensive care unit.
GWAS of Hematuria
Authors: Gagliano Taliun Sarah A. , Sulem Patrick , Sveinbjornsson Gardar , Gudbjartsson Daniel F. , Stefansson Kari , Paterson Andrew D. , Barua Moumita
Published: May 2022

Background and objectives

Glomerular hematuria has varied causes but can have a genetic basis, including Alport syndrome and IgA nephropathy.

Design, setting, participants, & measurements

We used summary statistics to identify genetic variants associated with hematuria in White British UK Biobank participants. Individuals with glomerular hematuria were enriched by excluding participants with genitourinary conditions. A strongly associated locus on chromosome 2 (COL4A4-COL4A3) was identified. The region was reimputed using the Trans-Omics for Precision Medicine Program followed by sequential rounds of regional conditional analysis, conditioning on previous genetic signals. Similarly, we applied conditional analysis to identify independent variants in the MHC region on chromosome 6 using imputed HLA haplotypes.

Results

In total, 16,866 hematuria cases and 391,420 controls were included. Cases had higher urinary albumin-creatinine compared with controls (women: 13.01 mg/g [8.05–21.33] versus 12.12 mg/g [7.61–19.29]; P<0.001; men: 8.85 mg/g [5.66–16.19] versus 7.52 mg/g [5.04–12.39]; P<0.001) and lower eGFR (women: 88±14 versus 90±13 ml/min per 1.72 m2; P<0.001; men: 87±15 versus 90±13 ml/min per 1.72 m2; P<0.001), supporting enrichment of glomerular hematuria. Variants at six loci (PDPN, COL4A4-COL4A3, HLA-B, SORL1, PLLP, and TGFB1) met genome-wide significance (P<5E-8). At chromosome 2, COL4A4 p.Ser969X (rs35138315; minor allele frequency=0.00035; P<7.95E-35; odds ratio, 87.3; 95% confidence interval, 47.9 to 159.0) had the most significant association, and two variants in the locus remained associated with hematuria after conditioning for this variant: COL4A3 p.Gly695Arg (rs200287952; minor allele frequency=0.00021; P<2.16E-7; odds ratio, 45.5; 95% confidence interval, 11.8 to 168.0) and a common COL4A4 intron 25 variant (not previously reported; rs58261427; minor allele frequency=0.214; P<2.00E-9; odds ratio, 1.09; 95% confidence interval, 1.06 to 1.12). Of the HLA haplotypes, HLA-B (*0801; minor allele frequency=0.14; P<4.41E-24; odds ratio, 0.84; 95% confidence interval, 0.82 to 0.88) displayed the most statistically significant association. For remaining loci, we identified three novel associations, which were replicated in the deCODE dataset for dipstick hematuria (nearest genes: PDPN, SORL1, and PLLP).

Conclusions

Our study identifies six loci associated with hematuria, including independent variants in COL4A4-COL4A3 and HLA-B. Additionally, three novel loci are reported, including an association with an intronic variant in PDPN expressed in the podocyte.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2022_04_26_CJN13711021.mp3
The Urgency of Doxing on Social Media Regulation and the Implementation of Right to Be Forgotten on Related Content for the Optimization of Data Privacy Protection in Indonesia
Authors: Cahya Yudiana Teguh , Dewi Rosadi Sinta , Soerjati Priowirjanto Enni
Published: May 2022

Data privacy that attached to every social media user has become a target of crime. One of the crime types that utilizes social media is doxing. Nowadays, the cases of doxing are increasing. There are still no specific and comprehensive normative rules that cover the data privacy protection to avoid doxing on social media. The fact makes the law enforcement still not optimal. This study is a descriptive study to answer some questions. Firstly, how to regulate doxing on social media based on the perspective of Indonesian law compared to the perspectives of other states in similar issue? Secondly, how the implementation of the right to be forgotten in doxing cases can optimize data privacy protection in Indonesia? This study used a normative juridical and case study approach. This study has resulted several results. Firstly, Indonesia needs special regulation for doxing on social media to protect the user data privacy. Secondly, the regulation of right to be forgotten should be reformulated and must be applied as a solution to doxing content. Doxing on social media regulation with the right to be forgotten can be further regulated through the legal regulation to provide a better data privacy protection.
Le poème aux origines de la philosophie
Authors: Gissoni de Santiago Lavelle Patricia , Cassin Barbara
Published: May 2022

Questions sur Parménide et Homère
Intercalação Hipotática Temporal entre sujeito e verbo em Língua Portuguesa e a (re)construção referencial
Authors: Cavalcante Sávio André de Souza
Published: May 2022

As cláusulas temporais que se intercalam entre sujeito e verbo têm função de orientação referencial, segundo Cavalcante (2020), embora o autor não a tenha especificado com detalhes. Nesse sentido, a partir de um diálogo entre o Funcionalismo linguístico e a Linguística Textual (NEVES, 2004; BRAGA; PAIVA, 2017), objetivamos verificar o modo como as temporais intercaladas entre sujeito e verbo servem à referenciação (MONDADA; DUBOIS, 2019 [1995]). O corpus desta investigação é composto de textos formais compilados pelo grupo de pesquisa NUPACT-UFJF. Após coleta de cláusulas temporais prototípicas, introduzidas pelo conector “quando”, localizamos 439 dados dessas cláusulas em distintas posições, entre as quais 75 eram intercaladas. Entre as intercaladas, apenas 9 tokens representavam o type sujeito-cláusula temporal-verbo, cujo referente sujeito é analisado sob a ótica dos processos referenciais (CAVALCANTE; MARTINS, 2020) e pelos parâmetros “definitude” (NEVES, 2013), “estatuto informacional” (PRINCE, 1992), “acessibilidade anafórica” e “persistência catafórica” (GIVÓN, 1995). Os resultados mostram que as temporais intercaladas podem servir a várias funções no processo de referenciação, dentro da função mais geral de (re)construção referencial: (i) focalizar determinado recorte na linha evolutiva temporal da existência de um referente, (ii) restringir um referente, (iii) recategorizar um referente, (iv) especificar um referente, (v) construir uma avaliação de um referente, (vi) retomar anaforicamente um referente, (vii) promover a topicalização de um referente, (viii) facilitar a referenciação tópica e (ix) explicitar uma mudança de perspectiva tópica. Confirma-se, portanto, a assunção de que os usos intercalados servem à (re)construção referencial nos textos e podem também contribuir para o dinamismo tópico das enunciações.
DIAGNÓSTICO DO DESCARTE DE CAROÇOS DE AÇAÍ EM MACAPÁ/AP E SUA UTILIZAÇÃO COMO INCREMENTO DE RENDA DOS BENEFICIADORES
Authors: Nascimento Marco Johnny de Oliveira do , Rempel Claudete
Published: May 2022

O processamento do fruto do açaí é uma realidade cultural importante para o desenvolvimento econômico e social da população da região Norte do país, pois é uma fonte de renda e de sustento de milhares de famílias que empreendem no ramo. O Brasil é o país que mais produz, consome e exporta açaí, que é um alimento muito procurado pelos consumidores no Estado do Amapá. A produção do vinho do açaí (líquido pastoso extraído após processamento), contudo, gera uma considerável quantidade de resíduos sólidos. O objetivo desta pesquisa é verificar como é o descarte de caroços de açaí no município de Macapá-AP e identificar formas de utilizá-lo como incremento de renda para os batedores. A pesquisa foi desenvolvida no Bairro Perpétuo Socorro - em Macapá. Para tanto, foi realizada uma pesquisa de campo em que foram entrevistados três grupos específicos que estão envolvidos na produção, fiscalização e descarte dos caroços de açaí. Os resultados demonstram que a produção dos resíduos dos caroços de açaí é maior que a demanda por estes em outras atividades econômicas existentes em Macapá, sendo grande parte dos caroços despejados em locais impróprios. É possível inferir, que o caroço de açaí tem potencial para ser reutilizado e gerar renda para os batedores, contudo, depende ainda do desenvolvimento de outras cadeias produtivas no Amapá e também de se viabilizar a comercialização destes para outros Estados e Países.
Nuclear Safety and Security in the Arctic: Crafting an Effective Regional Governance System
Authors: Lysenko Mikhail , Vylegzhanin Alexander , Young Oran
Published: May 2022

The Arctic is saturated with nuclear facilities bringing both benefits for regional economic and social development and risks of nuclear and radiological accidents and concerns about radioactive wastes. There is every reason to expect the Arctic will remain a nuclearized region during the foreseeable future. This makes it important to direct attention to issues of nuclear safety and security in the region. We identify several clusters of these issues in the Arctic, including the challenges of potential nuclear accidents, the handling of spent nuclear fuel and radioactive waste, the cleanup of radiological contaminants, and concerns about nuclear security. An analysis of international conventions and voluntary codes of conduct shows that they are applicable to Arctic nuclear safety and security, but only in general terms. This suggests a need for an Arctic-specific agreement on nuclear and radiological safety, emergency preparedness and response, and cleanup of radiological contaminants. The outbreak of military hostilities in Ukraine in February 2022 has disrupted normal procedures for addressing issues of common concern in the Arctic. But the need for co-operation regarding matters like nuclear safety and security will not go away. Assuming it is possible to devise “necessary modalities” for restarting the work of the Arctic Council following the acute phase of the Ukraine crisis, an Arctic-specific agreement on nuclear safety and security could be developed under the auspices of the Arctic Council, which already has taken an interest in nuclear safety through the activities of its Working Group on Emergency Prevention, Preparedness and Response. Once such an agreement is in place, it will become important to consider the infrastructure needed to ensure that its provisions are implemented effectively.
Задачі системи громадського здоров’я по формуванню у населення відповідального ставлення до особистого здоров’я
Authors: Качур О.Ю.
Published: May 2022

Матеріали та методи. Бібліосемантичний, структурно-логічного аналізу, соціологічний, статистичний. Соціологічним дослідженням охоплено 195 організаторів охорони здоров’я, 89 сімейних лікарів та 265 респондентів із числа дорослого населення. Статистичне опрацювання результатів опитування проводилося з використанням загальноприйнятих методів медичної статистики.Результати. Визначено зміст діяльності системи громадського здоров’я з формування у населення відповідального ставлення до особистого здоров’я. Найвищий рівень підтримки респондентів отримали наступні його складові: інформування населення про загрозливі для здоров’я та життя стани та такти дій при них; інформування населення про систему профілактичних оглядів; інформування населення про принципи первинної та вторинної профілактики захворювань; інформування населення про економічні переваги профілактики захворювань над лікуванням.Висновки. Використовуючи сучасні форми та методи діяльності система громадського здоров’я має можливість забезпечити формування у населення відповідального ставлення до особистого здоров’я.Ключові слова: населення, відповідальне ставлення, формування, система громадського здоров’я, задачі.
Частота захворюваності медичних працівників стоматологічного профілю
Authors: Мельник С.В. , Горзов Л.Ф. , Мельник В.С.
Published: May 2022

Мета: виявити особливості захворюваності на тимчасову втрату працездатності медичних працівників стоматологічного профілю.Матеріали та методи. Нами проведено аналіз показників захворюваності з тимчасовою втратою працездатності (ЗТВП) за період з 2018-2020 роки у медичних працівників стоматологічного профілю у порівнянні з працюючим населенням та медичними працівниками Закарпатської області. Джерелом статистичної інформації послужили дані із 1374 листків обліку тимчасової непрацездатності. Для поглибленого вивчення захворюваності використано аналіз самооцінки стану здоров’я 121 стоматолога-терапевта та даних їх медичних оглядів.Результати. Рівень захворюваності за кількістю випадків ЗТВП у фахівців стоматологічного профілю з усіх причин був у 1,9 разів вищий, ніж у населення Закарпаття, та у 1,5 разів вищий, ніж у медичних працівників загалом по області. По хворобі цей показник був у 2,1 та 1,6 разів, відповідно, вищим, ніж у порівнюваних групах.Висновки. Захворюваність на ЗТВП у медичних працівників стоматологічного профілю з усіх причин та захворювань, як по числу днів (1350,4 та 1240,9 дня, відповідно), так і за кількістю випадків непрацездатності (123,3 та 106,2 випадки, відповідно) у перекладі на 100 працюючих була вищою, ніж у працездатного населення та медичних працівників Закарпатської області.Ключові слова: захворюваність, захворюваність із тимчасовою втратою працездатності, медична активність, медичні працівники стоматологічного профілю, медичні огляди.
Exploring of the use of Political Correctness in World
Authors: Yuwana Akmal Wisnu , Cathrine Widya
Published: May 2022

As we understand, the use of political correctness is mainly to avoid and reduce the gap with those who are underprivileged in society. The more awareness that people have about PCs, the more peaceful life is because it avoids awakening of superiority and a sense of indifference. Though there are some controversies behind the banner of political correctness. Thus knowing political correctness is a double-edged sword when establishing communication with others. In this study, we aimed to investigate the use of political correctness in the current situation to increase knowledge among people during the running globalization times. Using sources from around the internet, we tried to uncover the impact of the political correctness world at large. This is qualitative research using library research to define what the role of Political Correctness in the world is.
Language Learning Strategies: How the Islamic Learners in IAIN Palopo Learn English
Authors: Iksan Muhammad
Published: May 2022

This study intended to describe the Language Learning Strategies that the English learners use in IAIN Palopo. This descriptive study involved 86 learners from the English Language Education Study Program as the research subject. The data in this study is gained using Adapted SILL Questionnaire, which Rebecca Oxford developed. Through the questionnaire, the study found that the English learners use all the categories of Language Learning Strategies, i.e., Memory Strategies, Cognitive Strategies, Compensation Strategies, Metacognitive Strategies, Affective, and Social Strategies. Furthermore, the level of the learners' LLSs use is categorized into Medium level. Metacognitive Strategies are the most popular strategies used by the learners (29%), followed by Affective Strategies (20,9%). In contrast, the Compensation Strategies (8%) become the least used strategies by the learners.
Effects of ultrasound/microwave irradiation on the sol-gel synthesis of titanium dioxide nanoparticles for photocatalyc application
Authors: Zarazua-Aguilar Y , Paredes-Carrera SP , Sánchez-Ochoa JC , Avendaño-Gómez JR , Flores-Valle SO
Published: May 2022

TiO2 nanoparticles were synthesized by the sol-gel method with the purpose of optimizing their morphological and structural properties, for their application in photocatalysis by varying the thermal treatment in the crystallization stage. Each sample was prepared according to the case with microwave irradiation (MO), ultrasound (US), combined mode (microwave-ultrasound (MC)) or conventional method (reflux), where the MC method has not been reported. It was found that the optical (edge energy (Eg)), textural and morphological properties depend on the type of irradiation during the crystallization stage. The SEM micrograms (scanning electron microscopy) showed two morphologies, one in the form of monoliths and the other as aggregates of lobular particles. In the case of MO and reflux, it is made up of aggregates of lobular particles, for US in the form of monoliths and finally for MC, the dominant morphology is due to the effect of US. For the evaluation in photocatalysis, it was observed in the samples studied that the higher the percentage of anatase phase, surface area, volume and pore size, all at the same Eg value, the greater the photodegradation of methyl orange. Therefore, TiO2 synthesized by the combined MC method was the best material obtained for photodegradation.
Absorption of grapiprant in red-tailed hawks (Buteo jamaicensis) is decreased when administered with food
Authors: Rodriguez Paula , Paul-Murphy Joanne R. , Knych Heather K. , Drazenovich Tracy L. , Hawkins Michelle G.
Published: May 2022

OBJECTIVE

Describe the pharmacokinetics of grapiprant administered orally with food to red-tailed hawks (RTHAs; Buteo jamaicensis) and compare the results with previously described grapiprant pharmacokinetics administered without food in this species.

ANIMALS

6 healthy adult RTHA (3 males, 3 females) under human care.

PROCEDURES

A single dose of grapiprant (30 mg/kg) was given orally to RTHAs, followed by force-feeding. Blood samples were obtained at 14 time points for 120 hours postgrapiprant administration. Plasma concentrations of grapiprant were measured via tandem liquid chromatography-mass spectrometry. Nonparametric superimposition using pharmacokinetic modeling software used plasma concentrations to calculate simulations of grapiprant plasma concentrations for 30 mg/kg administered orally with food every 12 hours.

RESULTS

The arithmetic mean maximum plasma concentration was 405.8 ng/mL, time to maximum plasma concentration was 16 hours, and harmonic mean terminal half-life was 15.6 hours. Simulations determined 30 mg/kg every 12 hours could attain minimum effective concentrations (> 164 ng/mL) reported in dogs for a sustained period of approximately 20 hours.

CLINICAL RELEVANCE

Grapiprant plasma concentrations were achieved above the canine therapeutic concentrations within 16 hours postmedication. Mean concentrations were maintained for approximately 20 hours. Simulations support a dosing frequency of 12-hour intervals with food reaching minimum effective concentrations established for canines, although it is unknown whether these plasma concentrations are therapeutic for birds. Bioaccumulation was not noted on simulations secondary to increased grapiprant administration. Further research including multidose assessments at this current dose with food, in vitro pharmacological characterization, and pharmacodynamic studies in this species are warranted.
How effective are hiring subsidies in reducing long-term unemployment among prime-aged jobseekers? Evidence from Belgium
Authors: Desiere Sam , Cockx Bart
Published: May 2022

Hiring subsidies are widely used to create (stable) employment for the long-term unemployed. This paper exploits the abolition of a hiring subsidy targeted at long-term unemployed jobseekers older than 45 years of age in Belgium to evaluate its effectiveness in the short and medium run. Based on a triple-difference methodology, the hiring subsidy is shown to increase the job-finding rate by 13% without any evidence of spillover effects. This effect is driven by a positive effect on individuals with at least a bachelor's degree. However, the hiring subsidy mainly creates temporary short-lived employment: eligible jobseekers are not more likely to find employment that lasts at least 12 consecutive months compared with ineligible jobseekers.
Effect of feeding of 10 % prefermented feed on fatty acid profile and oxidation changes in chicken breast meat
Authors: Bartkovský Martin , Marcinčáková Dana , Makiš Andrej , Klempová Tatiana , Semjon Boris , Roba Pavol , Marcinčák Slavomír
Published: May 2022

The aim of this work was to evaluate the effect of addition of 10 % fermented feed (FF) into commercial broiler feed on fatty acid profile, chemical composition and oxidative stability of chicken breast meat fat. FF was prepared by the process of fungal solid-state fermentation. Application of FF into the commercial feed mixtures resulted in increased content of gamma-linolenic and oleic acid in broiler breast meat (P < 0.05). Oxidative stability of meat fat was significantly higher in experimental broilers group fed diet with the addition of 10% FF (P < 0,05) after storage period of samples for seven days at temperature of 4 °C.
Influence of Non-Thermal Plasma (DBD) On Infertility Male Semen with Low Sperm Motility and Dna Damage
Authors: Mazhir Sabah N. , Hanon Marwa S. , Al-Ahmed Hazim I. , Haddad Reem A.
Published: May 2022

Non-thermal plasma(Dielectric barrier discharge) has many uses including living tissue sterilization, inactivation of the bacteria, excimer formation, angiogenesis, and surface treatment. This research aim is to use cold plasma as a tool to search the effect of the dielectric barrier discharge system at room temperature on human sperm motility and DNA integrity. This work was performed on 60 human semen samples suffering from low motility; each sample was prepared by centrifugation method, then each semen sample was divided into two sections, the first section is before significant exposure to the plasma system (DBD) and the second section is after treatment with the DBD system at ambient temperature. Before and after exposure to non-thermal Plasma (DBD), DNA integrity and sperm motility were assessed, patients suffered from asthenospermia has a high level of DNA fragmentation than fertile male, ( 24.16±4.14) p<0.001 for untreated and after treatment the semen slide with dielectric barrier discharge the percentage decreases to (9.16±1.76) p>0.006, and the comet slide was (35.44±4.15) then the percentage decline to (19.86 ±2.44) these results have shown that cold plasma improves sperm motility and decreases from DNA damage in patients with medium and high level of DNA damage.
A New Meaning of the Expression s.t-wr.t.: Place where the King is Crowned and Receives the Signs of the Sed-Festival
Authors:   Universitat de Barcelona (España), Costa Salvador , García Jordi , Magadá Teresa ,   Universitat de Barcelona (España)
Published: May 2022

The present article proposes a new connotation to the expression s.t-wr.t, “Great Place”, that could be added to the several meanings that Egyptology has already bestowed on this term. It will be shown that the s.t-wr.t could also refer to the place where, during the Ramesside period the king was crowned and received the signs of the Sed-Festival, as part of the ceremonies confirming royal power
The Dual Solar (Solstitial) and Cardinal Orientation in Planning the Middle Kingdom Funerary Complexes in Qubbet el-Hawa
Authors:   Universidad de Jaén (España), Martínez Hermoso Juan Antonio , Mozas Calvache Antonio T. ,   Universidad de Jaén (España), Pérez García José Luís ,   Universidad de Jaén (España)
Published: May 2022

The Qubbet el-Hawa necropolis, located on the west bank of the Nile, was the burial site chosen by the elite of Elephantine, from the Old Kingdom to the Middle Kingdom, and became one of the most important provincial cemeteries in the country. The hill affects the course of the River Nile and determines the disposition of the hypogea distributed between its two slopes (southeast and northeast). Therefore, the topography (and the river) determined the alignments of most of the tombs. During the Middle Kingdom, although only six large funerary complexes were built, there was a very significant change in the architecture of the necropolis in terms of the design of the burial chapels (which were planned as if they were a funerary temple), as well as the accuracy of the construction methods. In addition, they stand out because they were planned (and built) with a strongly symbolic double orientation, which is the subject of this study. The astronomical alignments of these funerary complexes, normally associated with royal temples and burials, appear to have been appropriated by the governors of Elephantine, lower-level officials, which has implications for our understanding of both Egyptian governance and Egyptian astronomy; undoubtedly, the architects had to possess knowledge of astronomy. The result is that these funerary complexes represent a clear example of “cultured” architecture carried out in a provincial cemetery. This article examines in detail the alignments of four of these funeral complexes: QH36, QH32, QH31 and QH33, building on the work of Belmonte and his collaborators in Qubbet el-Hawa, who are primarily responsible for increasing our data of Egyptian astronomical alignments
Online Patient Health Resources in Nonmelanoma Skin Cancer: An Assessment of Readability, Quality, and Comprehensiveness
Authors: Shih Terri , Brimacombe Allison , Shi Vivian , Hsiao Jennifer Lin
Published: May 2022

Background: Nonmelanoma skin cancer (NMSC), the most prevalent skin cancer, affects over 3 million in the United States annually. Although most patients search for health information on the internet, the readability and quality of NMSC online resources is unknown.
Objective: We examine the readability, quality, and comprehensiveness of content in NMSC websites.
Methods: Top 50 Google search results for “nonmelanoma skin cancer”, “basal cell skin cancer”, and “squamous cell skin cancer” were evaluated. Advertisements, blogs, scientific articles, and non-comprehensive, professional, and irrelevant sites were excluded. Six readability scales assessed readability. JAMA Benchmark and Discern Instrument assessed quality. Content was evaluated for comprehensiveness. Pearson’s correlation examined the relationship between readability and quality.
Results: Seventy-nine websites met inclusion criteria. Average readability level was 11th grade (range 6.8-17.9). No websites met the full criteria of JAMA Benchmark. Only 16.4% had “good”/“excellent” quality per Discern Instrument. Quality and readability scores were not correlated. Most websites discussed risk factors (87.3%), prevention (73.4%), and surgical (87.3%) and nonsurgical (82.3%) treatments. 50.6% included skin cancer images, of which only 17.5% were of skin of color patients.
Conclusion: Online NMSC resources need improved readability, quality, and diversity in their representation of skin types.
Endovascular management of iatrogenic vertebro-vertebral fistula: Black Swan event in C2 pedicle screw
Authors: Chaturvedi Jitender , Sudhakar P. Venkata , Gupta Mohit , Goyal Nishant , Mudgal Shiv Kumar , Gupta Priyanka , Burathoki Sandeep
Published: May 2022

Background:

Vertebro-vertebral fistulas (VVF) are rare. Anatomically, they consist of an arteriovenous fistula, a direct pathological communication between vertebral veins (including the epidural vertebral venous plexus) and extradural vertebral artery. The various etiologies include trauma, iatrogenic, or spontaneous (e.g., NF-1 or Ehlers Danlos Syndrome). The clinical presentation may include acute/delayed onset of radiculopathy and/or myelopathy. They may further be characterized by the delayed onset hearing loss to tinnitus and/or the sensation of water in the ear.

Case Description:

We report successful endovascular management for iatrogenic VVF in a 37-year-old female who was diagnosed with an odontoid fracture (Anderson type IIC). She underwent a posterior C1 lateral masses to C2 pedicle/laminar screw fixation. An intraoperative vertebro-vertebral fistulas (VVF) was recognized during the procedure and it was managed successfully with percutaneous transarterial endovascular coiling.

Conclusion:

Iatrogenic VVF should immediately be suspected when the implant trajectory goes slightly off track during a C1-2 fixation. Immediate postoperative DSA and MRI are advisable, irrespective of whether the patient is symptomatic. These lesions are best managed with endovascular coiling with or without detachable balloons.
Preoperative hypoalbuminemia and dialysis increase morbidity/mortality after spine surgery for primary pyogenic spinal infections (ACS-NSQIP Study)
Authors: Camino-Willhuber Gaston , Franklin Austin , Rosecrance Katherine , Oyadomari Sarah , Chan Justin , Holc Fernando , Hashmi Sohaib , Oh Michael , Bhatia Nitin , Emmerich Juan , Lee Yu-Po
Published: May 2022

Background:

We analyzed the role of hypoalbuminemia, dialysis, and other risk factors that increase morbidity/ mortality following surgery for primary pyogenic spinal infections (PSIs). The American College of Surgeons’ National Surgical Quality Improvement Program (ACS-NSQIP) that included 627 patients was utilized as our database.

Methods:

Primary spinal surgery for spondylodiscitis was evaluated in a ACS-NSQIP database involving 627 patients between 2010 and 2019. Outcome assessment included evaluation of 30-day postoperative morbidity, and mortality rates.

Results:

Within 30 postoperative days, complications occurred in 14.6% (92/627) of patients; 59 (9.4%) required readmission, and 39 (6.2%) required additional surgery. The most common complications were: wound infections, pneumonia, septic shock, and death (1.8%). Hypoalbuminemia (i.e., significantly associated with unplanned readmission and reoperation), and dialysis were the two major risk factors contributing to increased perioperative morbidity and mortality.

Conclusion:

Among 627 ACS-NSQIP patients undergoing primary surgery for PSIs, hypoalbuminemia and dialysis were associated with higher risks of major perioperative morbidity (i.e., within 30 postoperative days – mostly readmissions and reoperations) and mortality.
The Soviet Lubok of the First Half of the 1920s as a Form of Propaganda among the Peasantry
Authors: Esyunin Egor A.
Published: May 2022

The lubok of the 1920s is a little-studied page of Soviet art. The tradition of using lubki (popular prints) and folklore for revolutionary propaganda goes back to the 19th century. The first part of the article examines the cases of using the lubki in the revolutionary movement. The Narodniks were the first who used the lubok literature form for revolutionary propaganda among peasants. The Narodniks’ “ryazhenaya” (“mummer”) literature masked in lubok clothing both for the purposes of conspiracy and for attractiveness for the peasantry. Before the October Revolution, the lubok had been mainly used by the Narodniks and Socialist-Revolutionaries who positioned themselves as a peasant party. After the revolution, the Bolsheviks also used the lubok form when it was necessary to broadcast Marxist ideas to the countryside. For this purpose, they used Soviet popular prints (Soviet lubki) and lubok books (propaganda prints). The second part of the article is dedicated to Soviet popular prints. At first, the Soviet lubki were oriented in their pictorial form on old traditional folk prints, and in their texts — on folklore. They imitated folk speech and took over ditties (chastushki) from the new Soviet folklore. From the second half of the 1920s, the Soviet lubok started changing its form, transforming into a reproduction from realistic easel paintings. The third part of the article considers the lubok books and agro tales for peasants. There is shown that the Soviet lubok books in their form also resembled pre-revolutionary ones.
La linguistique spontanée des traceurs de frontières
Authors: Sériot Patrick
Published: May 2022

C’est du discours sur l’équivalence entre langue et nation comme objets naturels et distincts, et de la pratique qui en découle qu’il va être ici question. Le matériau en sera essentiellement les situations de confins en Europe centrale et orientale, propices à une réflexion sur les marges, les limites, les frontières, les seuils, tout ce qui fait que du continu peut être nommé, et donc pensé comme du discontinu.
Langues et métalangages : verbe et prédication chez Heymann Steinthal
Authors: Samain Didier
Published: May 2022

Héritier proclamé de Humboldt et initiateur avec Moritz Lazarus

(1824-1903) de la Völkerpsychologie, Heymann Steinthal (1823-1899) est traditionnellement considéré comme un représentant du courant «psychologique» en linguistique. L’un de ses premiers ouvrages (1855), qui multiplie les exemples de non concordance entre la «logique» et la «grammaire», se veut en effet une attaque en règle contre le «logicisme» qu’il impute à Becker et à la grammaire générale, en considérant notamment la prédication comme une propriété quasiment triviale (non spécifiquement grammaticale) du langage. Toutefois le sens de ces appellations n’est pas évident et les choses sont moins simples qu’il y paraît, car Steinthal emprunte en fait autant à ses ennemis déclarés qu’à Humboldt. Plusieurs faits méritent ici d’être soulignés. Premièrement, la généralisation qu’il fait subir à certains concepts classiques, et notamment à celui de prédicat, ce qui le conduit à une conception des relations dites «logiques» proche de celle des grammaires dépendancielles. Deuxièmement, le fait que la spécificité du plan grammatical soit définie, par contraste, dans le cadre d’une typologie basée sur le topos humboldtien du dynamisme de la phrase indo-européenne. Ces deux points, qui caractérisent la Mischsyntax un peu particulière à laquelle aboutit Steinthal, suggèrent qu’il n’y a pas de discontinuité tranchée entre théorie classique du jugement et grammaire dépendancielle. Ils posent aussi des questions épistémologiques plus générales, concernant notamment le lien unissant les objets empiriques (ici les langues) et les métalangages utilisés pour les décrire.