bluuebunny/crossref_metadata_2025 huggingface dataset:
Production of an Edible Food Packaging Film Using Hibiscus Sabdarifa Sepal Mucilage and Carboxymethyl Cellulose
Authors: Beigomi Maryam , Dashipour Alireza , Mashhadi Mohammad Amin , Mashhadi Farzaneh Farajian , Valizadeh Moharram
Published: September 2023

This research investigated the viability of using Hibiscus Sabdarifa sepal mucilage (HSSM) in conjunction with glycerol (10, 15 and 20%, w/w) and carboxymethyl cellulose (1%, w/w) to create a new biodegradable edible film. The microstructural, thermal, mechanical, physical, and antioxidant activities of the films made for use in the packaging sector were tested and assessed. Overall, the results demonstrated that increasing the percentage of glycerol in the optimal amount of Hibiscus Sabdarifa sepal mucilage increased the film thickness, moisture content, solubility, water vapor permeability, and elongation at break (EB%). Significant reductions were seen in the tensile strength, melting point, and glass transition temperature (Tg). The color of the films indicated that, despite becoming faintly green or crimson as the glycerol concentration increased, they remained transparent. In addition, the produced film exhibited notable antioxidant properties. Compared to films without glycerol, glycerol-containing film samples exhibited a uniform surface morphology devoid of cavities and fractures in electron microscope images. In combination with carboxymethyl cellulose, the sepal mucilage of Hibiscus Sabdarifa, a novel and innovative source, led to the production of biodegradable edible films with desirable properties.
Association between intraoperative noradrenaline infusion and outcomes in elderly patients undergoing major oncologic surgeries: A retrospective propensity score-matched cohort study
Authors: Yang Ya-Jun , Feng Yu-Mei , Wang Tong-Xuan , Wang Jing-Yun , Pang Qian-Yun , Liu Hong-Liang
Published: September 2023

Background:Noradrenaline (NA) is commonly used intraoperatively to prevent fluid overload and maintain hemodynamic stability. Animal and clinical studies provided inconsistent results concerning the effect of NA on postoperative outcomes. As aging is accompanied with various diseases and has the high possibility of the risk for postoperative complications, we hypothesized that intraoperative NA infusion in elderly patients undergoing major oncologic surgeries might potentially exert adverse outcomes.
Methods: In this retrospective propensity score-matched cohort study, elderly patients undergoing major oncologic surgeries were selected, 1837 receiving NA infusion during surgery, and 1072 not receiving NA. The propensity score matching was conducted with a 1:1 ratio and 1072 patients were included in each group. The primary outcomes were postoperative in-hospital mortality and complications.
Results:Intraoperative NA administration reduced postoperative urinary tract infection (OR:0.124, 95% CI: 0.016-0.995), and had no effect on other postoperative complications and mortality, it reduced intraoperative crystalloid infusion (OR:0.999, 95% CI: 0.999-0.999), blood loss (OR: 0.998, 95% CI: 0.998-0.999), transfusion (OR:0.327, 95% CI: 0.218-0.490), but increased intraoperative lactate production (OR:1.354, 95% CI: 1.051-1.744), and hospital stay (OR:1.019, 95% CI: 1.008-1.029).
Conclusions: Noradrenaline has little impact on postoperative complications and mortality in elderly patients undergoing major oncologic surgeries, and can be safely administered intraoperatively.
Digitales Schulbuch zwischen Nutzungspotenzial und Nutzungspraxis
Authors: Totter Alexandra , Müller-Kuhn Daniela , Keller-Lee Marlies , Rast Christine
Published: September 2023

Die Entwicklung digitaler Schulbücher hebt die Trennung zwischen digitalen Medien und dem Leitmedium Schulbuch auf. Dadurch ergibt sich für den Fremdsprachenunterricht eine Vielzahl von Nutzungspotenzialen. Inwiefern Schüler:innen diese Potenziale tatsächlich nutzen, wird anhand einer empirischen Studie zur Schulbuchnutzung untersucht. Basierend auf einer Analyse von Strukturelementen eines Kapitels werden die Potenziale eines digitalen Französischlehrmittels differenziert betrachtet. Die Befunde deuten auf eine Reihe von Potenzialen und ein umfassendes Angebot hin. Vergleicht man diese mit den Ergebnissen der Nutzungspraxis der Schüler:innen, wird deutlich, dass dieses Angebot weit über die tatsächliche Nutzung hinausgeht. Bislang wird das medien- und fachdidaktische Potenzial digitaler Lehrmittel nur teilweise ausgeschöpft. Ergänzt werden diese Befunde um eine Analyse möglicher Zusammenhänge zwischen der Nutzung verschiedener Strukturelemente des Lehrmittels und Personenmerkmalen der Schüler:innen. Inwiefern verschiedene Merkmale die Nutzung digitaler Lehrmittel beeinflussen, wird abschliessend diskutiert.
Projective cluster-additive transformation for quantum lattice models
Authors: Hörmann Max , Schmidt Kai P.
Published: September 2023

We construct a projection-based cluster-additive transformation that
block-diagonalizes wide classes of lattice Hamiltonians
\mathcal{H}=\mathcal{H}_0 +Vℋ=ℋ0+V.
Its cluster additivity is an essential ingredient to set up perturbative
or non-perturbative linked-cluster expansions for degenerate excitation
subspaces of \mathcal{H}_0ℋ0.
Our transformation generalizes the minimal transformation known amongst
others under the names Takahashi’s transformation, Schrieffer-Wolff
transformation, des Cloiseaux effective Hamiltonian, canonical van Vleck
effective Hamiltonian or two-block orthogonalization method. The
effective cluster-additive Hamiltonian and the transformation for a
given subspace of \mathcal{H}ℋ,
that is adiabatically connected to the eigenspace of
\mathcal{H}_0ℋ0
with eigenvalue e_0^ne0n,
solely depends on the eigenspaces of \mathcal{H}ℋ
connected to e_0^me0m
with e_0^m\leq e_0^ne0m≤e0n. In contrast, other cluster-additive transformations like the
multi-block orthogonalization method or perturbative continuous unitary
transformations need a larger basis. This can be exploited to implement
the transformation efficiently both perturbatively and
non-perturbatively. As a benchmark, we perform perturbative and
non-perturbative linked-cluster expansions in the low-field ordered
phase of the transverse-field Ising model on the square lattice for
single spin-flips and two spin-flip bound-states.
Shaping Factor of the Normative Behavior of the Catholic Believers
Authors: Driyanto Yohanes , Soelasih Yasintha
Published: September 2023

The research aimed to examine the effect of Jesus’ communication, attitude, and action on the perception and normative behavior of Catholics. The level of interpretation and observance of the Canon Law by Catholic believers was relatively low. The Bible told about Jesus conveying His teaching by putting it down into communication, His way of having an attitude, and His example in taking action. The research was based on the cognitive-affective-conative model. Cognitive referred to knowledge or information conveyed commonly in communication, affective was related to emotion or feeling manifested in attitude, and conative was about doing or action. Normative behavior was the way people behave, taking the basis of their understanding and feeling in accordance with the Canon Law. The novelty of research on the application of the concept of consumer behavior in the life of the Church was based on the teachings of Jesus. Data collection was carried out by non-probability with purposive sampling. The questionnaires were distributed using G-form via WhatsApp, and 297 respondents participated. The data were then processed using Structural Equation Modeling with the Smart PLS 3.0 application to test the reliability, validity, and hypotheses. The results of the hypothesis test show that all are rejected. The variables of communication, attitude, action, believer’s perception, and normative behavior on the object of religion show that the theory of behavior on these variables does not support previous research.
Keeping Tradition, Culture, and Community through Social Entrepreneurship: A Case of Lamerenan
Authors: Harnadi Agnes , Sijabat Rosdiana , Widyastuti Pristiana , Singgalen Yerik Afrianto
Published: September 2023

The research discussed social entrepreneurship that aimed to create social impacts. These impacts could be not only economic, yet cultural. Lamerenan was a social enterprise focused on Tanimbar’s tenun cloth (handwoven fabric) through community empowerment. This foundation was chosen because it encouraged the local community to preserve tradition and culture by persuading them to use traditional methods to produce the cloth. Although this foundation was categorized as a micro-small-medium enterprise (MSME) with age less than ten years old, Lamerenan had a mission to restore the quality of Tanimbar’s tenun cloth, by keeping the tradition using traditional weaving loom, which was called “Tenun Gedog Loom” or “Gedogan” and natural dyes. The research utilized the qualitative method. An in-depth interview was conducted with the founder of Lamerenan, Hiyashinta Klise, on December 2021 via Zoom meeting. Secondary data about Lamerenan and Tanimbar’s tenun cloth was collected from online news and Lamerenan’s social media (Instagram). The research finds how Lamerenan keeps the Tanimbar’s weaving tradition, culture, and women weaver community through social entrepreneurship. Furthermore, how the community returns to the traditional way, using natural dyes in producing the cloth. The result of the research is expected to bring insight into local traditions and culture that can be useful in developing empowerment in the local community.
Agenda Setting within ASEAN: Thickening, Broadening, and Breaking Pressures
Authors: Ashley Ryan
Published: September 2023

The Association of Southeast Asian Nations (ASEAN) is a clear example of an “organized anarchy” within agenda setting literature; meaning that ASEAN has problematic preferences due to its multiple conflicting goals, relies on unclear methods to accomplish those goals, and experiences fluid participation of its members and leaders. This leaves the organization a case study in the path dependency of norms, as ASEAN typically defaults to its founding principles of non-interference, economic inter-connectivity, and regional “centrality” during crises. The research question was on the examples of variation when ASEAN broadens the scope of its mission. The research aimed to answer by framing ASEAN as a subsystem of Southeast Asian regionalism and conducting a comparative historical analysis of three case study periods: the creation of the ASEAN Regional Forum (ARF), the failure to reach a joint communique in 2012 over tensions in the South China Sea, and the ongoing crisis of human rights and governance in Myanmar. The case studies demonstrate that the most effective broadening forces for ASEAN are exogenous. The conclusion argues that this is a problematic status quo for a regional organization that seeks to promote its centrality to counter interference from outside powers.
Indonesia’s Strategic Narrative on the New Dynamics of Great Power Rivalry in the Indo-Pacific
Authors: Riyanto Budi , Djumala Darmansjah , Tan Youzhi
Published: September 2023

Given the rising political tensions between the two great powers, the United States (U.S.) and the People's Republic of China (PRC), a geopolitical shift to the Indo-Pacific region is critical momment in the 21st century. Ideological, economic, military and technological aspects of this new struggle appear to be sharpening. In the current geopolitical change in the Indo-Pacific, two concerns that have not received much attention are addressed in the research, namely the importance of strategic narrative competition in the global information era and the part played by Indonesia in terms of its strategic narratives as a nation in the center of Indo-Pacific geopolitics. By focusing on the interaction of each actor in projecting a story about the order in the new world system, encouraging actors to adapt to their identities and roles in the story, and enacting policies that are in line with their interests, strategic narrative studies have the potential to explore geopolitical issues more thoroughly. Indonesia positions itself actively in a strategic narrative construction that can compete, and create a strategic role that can be played in accordance with its interests rather than playing a passive role and only becoming a victim in the face of the strategic narrative contestation among the great powers. The strategic narrative of Indonesia as it relates to identity, policy, and system is specifically examined in the research. It also examines the role that Indonesia plays in the formulation and projection of the narratives, as well as how the narratives are received in the context of the emerging Indo-Pacific's geopolitical struggle. As a middle power, Indonesia offers a shared strategic narrative that promotes a goal of greater cooperation, hence reducing great power rivalry.
Acute-phase proteins and blood parameters as potential additional markers for ante-mortem tuberculosis diagnosis in European bison (Bison bonasus)
Authors: DIDKOWSKA ANNA , ORŁOWSKA BLANKA , KRAJEWSKA-WĘDZINA MONIKA , WIŚNIEWSKI JAN , ANUSZ KRZYSZTOF
Published: September 2023

According to the International Union for Conservation of Nature, European bison (Bison bonasus) is a vulnerable species. European bison is susceptible to mycobacterial infections, as evidenced by numerous confirmed tuberculosis cases in this species. Diagnostic methods for tuberculosis have developed significantly in recent years, but performing several parallel tests (serological, microbiological, molecular, cell-mediated based tests) is still the most appropriate algorithm to confirm or exclude Mycobacterium tuberculosis complex infection in this species. This study primarily aimed to determine whether some additional biomarkers could be helpful in tuberculosis diagnosis in European bison. Whole blood and serum from eight European bison with known TB status were used for the study. Four of these bison were Mycobacterium caprae-positive and four were M. caprae-negative. The material was tested for basic hematological and biochemical parameters and three selected acute phase proteins: ceruloplasmin, haptoglobin, and serum amyloid A (SAA). The study found no significant changes in biochemical or hematological parameters in European bison with tuberculosis, but one European bison with the most advanced tuberculosis lesions showed increased concentrations of haptoglobin and SAA. These preliminary studies show that determining the concentrations of acute-phase proteins could be an additional supportive tool that can be used to diagnose tuberculosis or to determine its severity. Further research is needed with an increased number of individuals.
Extremismo político e crise hegemônica
Authors: Motta Barbara , Nascimento Forner Clarissa , Peres Milani Lívia
Published: September 2023

O artigo visa contribuir ao debate sobre a nova direita global, analisando as transformaçõessociopolíticas observadas nos Estados Unidos da América (EUA), durante a administraçãoTrump. Os casos de três das milícias mais relevantes naquele país – os Oath Keepers, osProud Boys e os Three Percenters – foram escolhidos para ilustrar como a ascensão de gruposde extrema direita e a contestação de valores liberais nos EUA transcendem o trumpismo,mas estão conectados com a hegemonia interna enfraquecida e a crise da ordem liberalinternacional. Metodologicamente, o trabalho se alicerça na análise de conteúdo parainvestigar os manifestos produzidos por essas organizações.
Tabu Search with Variable Neighborhood Search Algorithm for Home Healthcare Routing Problem for Multiple Hospitals with Balanced Workload
Authors: DİNÇ YALÇIN Gülçin , YAVUZ Tuğçe , ALTINTAŞ Şüheda
Published: September 2023

In this paper, we study home healthcare routing and scheduling problem where multiple hospitals serve patients. In the public hospitals in healthcare system of Türkiye, patients requiring home healthcare are assigned to the hospital that serves their place of residence. This can cause the workload of hospitals to become unbalanced in terms of the time needed for both traveling and operation. The aim of this paper is to generate routes with a balanced workload for hospitals, giving consideration to the time windows of patients and the working hours of health workers. Firstly, we construct a mathematical model which can solve toy and small-scale problems whilst taking into account the importance of a balanced workload. Then, a Tabu Search with a Variable Neighborhood Search (TS-VNS) algorithm is developed to solve large-scale problems. The performance of the TS-VNS algorithm is tested by comparing the results of the mathematical model with the generated test problems at a small scale. Additionally, large-scale test problems from the literature are sourced for the problem and solved by the TS-VNS algorithm. The results demonstrate the efficiency of the TS-VNS algorithm.
O NOVO MODELO DE CONCESSÃO DE BOLSAS CAPES: O FATOR IDHM E OS REFLEXOS PARA OS PROGRAMAS DA ÁREA EDUCAÇÃO NA AMAZÔNIA
Authors: Maia Garcia Fabiane , Santos Magalhães Luciano
Published: September 2023

O texto apresenta o recorte de uma pesquisa em andamento sobre a política de avaliação da pós-graduação na Amazônia. Investigamos o novo formato de distribuição de bolsas Capes e seus reflexos para os programas de pós-graduação em educação (PPGEs) na região. A pesquisa é documental e discute à luz do Plano Nacional de Pós-Graduação (PNPG) 2011-2020 e de atos que instituem o modelo em andamento. O fator IDHM para a concessão de bolsas é vantajoso aos PPGEs, mas incerto enquanto não for contemplado em um PNPG e instituído como medida permanente da Capes ao invés de portarias anuais de concessão.
Palavras-chave: Pós-Graduação; Fomento; Bolsas Capes; IDHM; Amazônia.
Improving the remote sensing process of evapotranspiration in the SEBAL algorithm using meta-heuristic models
Authors: Komasi Mehdi , Sharghi Soroush
Published: September 2023

This paper investigated how the meta-heuristic models can be used to facilitate the estimation of evapotranspiration (ET) images. Focusing on estimating daily ET directly from received images of the electromagnetic bands of Landsat 8 satellite utilizing metaheuristic models, authors used daily ET images estimated by the SEBAL algorithm to calibrate and verify these models. The results of this research showed that the ANN model with DC and RMSE of 0.98 and 0.09025 mm/day, respectively, is more accurate compared to the ACO (with DC = 0.65 and RMSE = 1.45 mm/day) and PSO (with DC = 0.23 and RMSE = 1.60 mm/day) models in the verification stage in estimating daily ET images. The ACO model compared to the PSO model is more accurate in estimating ET images with DC of 0.65 and 0.23 in the verification step, respectively. While removing half of the training data, the accuracy of the PSO model surpasses the ACO model with DC of 0.85 and 0.80, respectively. Also, the ANN model is more accurate than the other two models in estimating ET, both when considering all the data and half of the training data (with DC = 0.98 and RMSE = 0.09 mm/day).
The relationship between the reasons for doing and not doing sports and sports awareness in university students: A cross-sectional study
Authors: ABAKAY Hanife , DERE Tuğba , AKBAYRAK Türkan
Published: September 2023

Aim: The aim of this study was to determine the level of sports awareness and reasons for university students doing or not doing sports, and to investigate the relationship between these two parameters.

Methods: The study included 479 university students from different provinces of Turkey, who were literate in Turkish. The sports habits of the students were evaluated using the Reasons for Doing and Not Doing Sports Questionnaire, and the level of sports awareness with the Sports Awareness Scale. All the data were collected online using a questionnaire created on Google Forms.

Results: The sport most frequently played by university students was determined to be volleyball (39.45%). The most common reason for not doing sport was physical reasons (1.35±1.23). The mean total score of the Sports Awareness Scale was 107.08±20.70. A statistically significant, weak positive correlation was determined between the subparameters of the Reasons for Doing Sport and all the subparameters of the Sports Awareness Scale, and with the exception of Insufficient Time, a statistically significant, weak negative correlation was determined between the subparameters of the Reasons for Not Doing Sport and the Sports Awareness Scale (p
Engenharia, gênero e formação em ciências exatas
Authors: Assumpção Georgia , Ferreira Amanda , Candido Júlia , Halegua Paula , Castro Alexandre
Published: September 2023

Esse artigo tem como propósito realizar uma análise da participação feminina em cursos superiores da área de ciências exatas, notadamente nas engenharias, em que há maior participação de discentes e docentes do sexo masculino. A metodologia utilizada incluiu a aplicação de questionário a alunas e alunos de uma instituição de ensino superior, – o Centro Federal de Educação Tecnológica Celso Suckow da Fonseca – que oferece, majoritariamente, cursos na área de ciências exatas. A discussão de resultados, pautada pelo referencial de estudos de gênero, incorporou análises quantitativas e qualitativas e assim constatou que os cursos de engenharia investigados mantêm práticas discursivas e relações de poder sexualizadas, implicadas na dominação masculina hegemônica dentro desse segmento profissional.
Trajetórias de mulheres mestras do CEFET-MG em áreas de humanas e de tecnologia
Authors: Guimarães Camila
Published: September 2023

As mulheres vêm conquistando mais espaço no mercado e na academia, porém as relações desenvolvidas nessas esferas continuam sendo marcadas por sexismo e estereótipos. Diante desse cenário, esta pesquisa objetivou, no plano geral, compreender a divisão sexual do trabalho e, mais especificamente, desvelar as dificuldades, o sexismo, os estereótipos e os marcadores de gênero nas escolhas realizadas por mulheres que concluíram mestrado pelo Centro Federal de Educação Tecnológica de Minas Gerais (CEFET-MG), no período de 2005 a 2016, bem como as estratégias de resistência desenvolvidas pelas egressas. Utilizou-se, então, uma metodologia de abordagem qualitativa, mediante pesquisa bibliográfica, levantamento de currículos Lattes e entrevista semiestruturada, cujas respostas foram analisadas em exegese fundamentada na revisão da literatura. Os achados sugerem que as trajetórias das mulheres foram marcadas por dificuldades e estratégias de resistências, de forma que alcançaram elevada ascensão nas suas carreiras devido à dedicação com vistas a obter maior qualificação profissional, vencendo preconceitos e dificuldades para estudar, em função de tripla jornada de trabalho, tarefas domésticas, cuidados com os filhos e a família e realização dos estudos. Conclui-se que a pesquisa corrobora estudos anteriores sobre a permanente clivagem entre os sexos nas áreas de conhecimento e de trabalho consideradas Humanas e sociais e outras de caráter científico e tecnológico, à luz dos princípios norteadores da divisão sexual do trabalho, segundo os quais existem trabalhos destinados às mulheres e trabalhos destinados aos homens e que o trabalho do homem tem um valor social e econômico maior do que o da mulher.
MARKETING DIGITAL EM UNIDADES DE INFORMAÇÃO
Authors: Francisco de Lima Antonia Lucineide , De Oliveira Brasil Marcus Vinicius , da Silva Candido Luiz Felipe
Published: September 2023

O uso das estratégias do marketing por unidade de informação ainda é algo novo na área de Ciência da Informação. O presente artigo tem como intuito, identificar as estratégias de marketing digital utilizadas para a disseminação da informação em unidades de informação em Instituições de Ensino Superior. A pesquisa se apresenta como exploratória de campo com análise descritiva e qualitativa. Após levantamento dos dados, pode-se concluir que existe uma compreensão por parte dos gestores das bibliotecas pesquisadas sobre o quanto um Sistema de Informação de Marketing - SIM, no que se refere ao planejamento e  divulgação dos serviços ofertados pelas unidades de informação, os participantes reconhecem como o uso do marketing é um valioso recurso para a solidificação da marca das bibliotecas, bem como para seu empenho de ofertar um serviço de qualidade e eficácia, que visa atender as necessidades dos usuários.
Axial Involvement in Psoriatic Arthritis: A Cross-sectional Clinical and
Radiologic Studies
Authors: Elsawy Noha A. , Farahat Shaimaa E. , El Shafei Mohamed M. , Elnemr Rehab
Published: September 2023

Objective:

This study aimed to investigate spinal involvement in psoriatic arthritis (PsA)
patients using clinical and radiographic methods

Methods:

A cross-sectional clinical study was conducted on 50 PsA patients diagnosed according
to the CASPAR criteria. Clinical examinations and functional assessments were performed. A radiographic
assessment of the spine was performed.

Results:

Out of 50 PsA patients (mean age of 45.50 ± 9.90 years), (males and females constituted
27 (54.0%) and 23 (46.0%) respectively), 76% had radiological axial involvement; (26%) with inflammatory
axial pain and (50%) without inflammatory axial pain (subclinical). Three axial radiographic
patterns were detected including spondylitis without sacroiliitis (15.78%), spondylitis with
sacroiliitis (78.94%), and sacroiliitis without spondylitis (5.26%).
In axial PsA patients, males were more affected than females (χ2=11.679, p = 0.003), with older
age (H = 15.817, p < 0.001) and higher body mass index (BMI) (F = 5.145, p = 0.010), increased
psoriasis duration (H = 9.826, p = 0.007) and severity (Η=25.171, p < 0.001), and more spinal
movement limitations than PsA patients without axial involvement (F = 26.568, p < 0.001).
Cervical involvement was higher than lumbar involvement. Axial radiographic severity assessed
by the PsA Spondylitis Radiology Index was associated with increased disability as assessed by the
Health assessment questionnaire (rs = 0.533, p = 0.001) and decreased quality of life assessed by
short form-36 score (rs = -0.321, p = 0.050).

Conclusions:

This study shows that a high percentage of PsA patients had axial involvement with a
high percentage of them having asymptomatic radiological findings. The cervical spine is more frequently
and severely affected than the lumbar spine. Axial PsA occurs in males more than females
with characteristic older age and higher BMI, increased psoriasis duration, and more limitation of
spinal mobility.
Cancer Stem Cells in Carcinogenesis and Potential Role in Pancreatic Cancer
Authors: Sharma Rishav , Malviya Rishabha
Published: September 2023

:

A poor prognosis is associated with pancreatic cancer because of resistance during treatment
and early distant metastases. The discovery of cancer stem cells has opened up novel avenues
for research into the biology and treatment of cancer. Many investigations have pointed out the role
of these types of stem cells in the oncogenesis and progression of hematologic and solid malignancies,
specifically. Due to the existence of cancer stem cells in the proliferation and preservation of
pancreatic tumors, such malignancies could be difficult to eradicate using conventional treatment
techniques like chemotherapy and radiotherapy. It is hypothesized that pancreatic malignancies
originate from a limited population of aberrant cancer stem cells to promote carcinogenesis, tumour
metastasis, and therapeutic resistance. This review examines the role of pancreatic cancer
stem cells in this disease and their significance in carcinogenesis, as well as the signals which modulate
them, and also examines the ongoing clinical studies that are now being conducted with pancreatic
stem cells.
Advances in Microneedle-Based Approaches for Skin Diseases: A
Comprehensive Review of Therapeutic Applications and Future Perspectives
Authors: Kumar Suraj , Sharma Pramod Kumar , Malviya Rishabha , Alam Aftab , Sagar Sakshi
Published: September 2023

Background:

Psoriasis is a persistent skin condition for which only symptom management is currently available. Topical and systemic medicines, physical therapy, and other methods are all part of the standard treatment strategy. New medication delivery methods for psoriasis are urgently needed because of the present methods' shortcomings.

Objective:

The objective of this article is to provide a comprehensive description of microneedles as well as their development in the treatment of psoriasis and the clinical challenges associated with them.

Discussion:

The microneedle (MNs) technology is better than other transdermal delivery methods because it has so many benefits, including low invasiveness, painlessness, simplicity, and enhanced patient compliance. Coated microneedles, hollow microneedles, dissolving microneedles, and solid microneedles are the four basic categories into which researchers have so far sorted the fast-expanding area of microneedles. Each of these kinds of microneedles offers its own unique advantages due to their unique properties and layout.

Conclusion:

MNs may significantly improve transdermal medication penetration by mechanically opening skin micropores. Meanwhile, this method demonstrates distinct benefits over injection and oral delivery, such as painless application, the least amount of intrusion, the simplicity of self-administration, and avoiding the first-pass impact.
Ethnopharmacological Insights on Therapeutic Potential of Oleanolic
Acid: A Review
Authors: Bhardwaj Hemlata , Vasudeva Neeru , Sharma Sunil , Kapoor Archana
Published: September 2023

Introduction:

Plants have long been utilised as a supplement or alternative treatment for
chronic conditions due to their therapeutic capabilities.

Objectives:

The objective of this study is to explore the ethnopharmacological aspects and therapeutic potential of naturally occurring oleanolic acid.

Method:

Information regarding oleanolic acid was collected from electronic databases, such as
ScienceDirect, Web of Science, PubMed, Springer, Journal websites, Google Scholar, Taylor and
Francis, Scopus and Wiley Online Library.

Result:

The article covered a wide range of immunomodulatory, antihypertensive, anticancer, antiinflammatory, antianxiety, antidepressant, antiischemic, antiviral, and other effects of triterpenoids.
One such triterpenoid is oleanolic acid, which was reported to be present in a number of plants
with a wide range of pharmacological potential. This article discussed the promising possibilities
for alternative neurodegenerative disease treatment and management through oleanolic acid and its
derivatives.

Conclusion:

The goal of this systematic review was to review the medicinal importance of
oleanolic acid, extracted from a variety of plants used as a dietary source, such as apple, pomegranate, lemon, grapes, pears, olive, a highly powerful molecule with a wide range of biological
actions, such as anti-microbial, anti-viral, anti-diabetic, hepatoprotective, antihypertensive, antiinflammatory, anticancer, anti-ischemic, antiviral, and cytotoxic properties.
overview of research literature on the management of development of university teacher training programs in the education field
Authors: Bouttavong Phetdalaphone
Published: September 2023

This paper focuses on researching issues related to the management and development of teacher education programs at the university level. In the context of an ever-changing and complex society, the development of university teacher education programs becomes of utmost importance. These programs not only ensure a solid foundation of subject matter expertise but also aim to foster pedagogical skills, refine teaching abilities, and concurrently address the practical demands of the education sector. However, during the process of managing and advancing university teacher education programs, various issues and challenges have emerged. These encompass but are not limited to, updating teaching content in alignment with emerging trends, ensuring the applicability and practicality of knowledge, developing modern teaching methodologies, and integrating information technology into the learning process. Furthermore, establishing a dynamic learning environment and actively encouraging student participation are also noteworthy challenges. Additionally, ensuring that education programs meet the highest standards of quality and international benchmarks is a critical consideration. Hence, the research into issues related to the management and development of university teacher education programs becomes imperative. This endeavour seeks to examine deficiencies and gaps in the management process, thereby proposing specific and progressive solutions.
Kajian Potensi Pemanfaatan Waduk Bener Untuk Pemenuhan Air Baku dan Air Irigasi
Authors: Pratiwi Mitha Aprilia , Jayadi Rachmad , Kironoto Bambang Agus
Published: September 2023

Waduk Bener merupakan waduk serbaguna yang memanfaatkan air DAS Bogowonto sebagai bagian dari Wilayah Sungai Serayu-Bogowonto untuk pemenuhan layanan air baku, air irigasi dan pembangkit listrik tenaga mikrohidro. Penelitian ini bertujuan untuk mengoptimasi air untuk memenuhi kebutuhan air irigasi dan air baku. Ketersediaan air dihitung menggunakan alihragam hujan-aliran metode Mock. Optimasi pengaturan release air waduk menggunakan metode Program Linier berbasis prinsip neraca air waduk dengan inflow debit tengah bulanan untuk aliran tahun basah, normal dan kering. Optimasi dilakukan dengan tiga skenario kondisi kebutuhan air baku yaitu kondisi eksisting, kondisi 25 dan 50 tahun. Simulasi pemanfaatan air waduk menggunakan metode Standard Operating Rule (SOR) menunjukkan nilai intensitas tanam tahunan berkisar 247,62%-292,81%. Hasil optimasi menunjukkan peningkatan intensitas tanam tahunan mencapai 287,24%-300% dengan reliabilitas layanan kebutuhan air sebesar 100% serta rerata faktor k untuk air irigasi dan air baku yang memenuhi persyaratan yang ditetapkan.
Evaluasi District Metered Area (DMA) pada Zona Air Minum Prima PDAM Kota Padang Panjang
Authors: Tanaka Wahyu , Komala Puti Sri , Helard Denny
Published: September 2023

Zona Air Minum Prima (ZAMP) Silaing Bawah Kota Padang Panjang memiliki 2 (dua) pipa jaringan distribusi yaitu DMA 01 dan DMA 02. Untuk menentukan performa DMA maka dilakukan analisis Non Revenue Water (NRW), Infrastructure Leakage Index (ILI) dan Uji Kinerja Hidrolis dengan Epanet. Pada penelitian ini, didapatkan hasil analisis NRW untuk DMA 01 dan DMA 02 sebesar 46,51% dan 54,42 % masing-masing, dimana hasilnya masih diatas PerMen PU No 20/PRT/M/2006 yang dipersyaratkan yaitu 20%. Sedangkan nilai ILI untuk DMA 01 dan DMA 02 adalah sama yaitu ILI > 16, kategori D (buruk). Untuk hasil analisis Epanet, dipantau sebanyak 41 pipa pada DMA 01 dan 21 pipa pada DMA 02 menunjukkan hasil nilai tekanan serta residu chlorine pada aliran DMA 01 dan DMA 02 semua titik memenuhi standar yaitu P > 0,5 bar dan residu chlorine > 0,22 dan 0,23 mg/l masing-masing. Ditinjau dari nilai velocity, pada DMA 01 (9 pipa) dan DMA 02 (8 pipa) dibawah standar yaitu < 0,3 m/s. Untuk nilai head loss sendiri pada DMA 01 (13 pipa) dan DMA 02 (5 pipa) juga melebihi standar yaitu > 10m/km.
Kalibrasi Model Mock pada Stasiun AWLR di Wilayah Sungai Lombok
Authors: Noviadi Satia Cahya
Published: September 2023

Di Indonesia terdapat pemodelan ketersediaan air seperti metode Nreca, Tanki, Mock maupun Artificial Neural Network (ANN).  Pada penelitian ini dilakukan kalibrasi model hujan-aliran menggunakan model Mock pada beberapa Daerah Aliran Sungai (DAS) di Wilayah Sungai (WS) Lombok yang memiliki stasiun Automatic Water Level Recorder (AWLR). Hal ini dikarenakan model Mock sangat cocok untuk kalibrasi model rain run di WS Lombok yang memiliki sungai dengan tipe perennial.  Penelitian ini melakukan analisis menggunakan model rain run Mock dengan input berupa data curah hujan, data evaporasi, data debit, dan data fisik DAS. Kalibrasi model Mock pada 19 stasiun AWLR dalam WS Lombok mendapatkan hasil 11 stasiun AWLR memiliki korelasi ≥ 70% yang menunjukan korelasi tinggi atau memiliki hubungan yang sangat erat antar variabel dan 8 stasiun AWLR memiliki korelasi antara ≥ 40% dan < 70% yang menunjukan korelasi sedang atau memiliki hubungan cukup erat antar variabel. Sedangkan terdapat 10 stasiun AWLR yang memiliki error ≤ 30% dan 9 stasiun yang memiliki error > 30%.  Beberapa error yang tinggi pada kalibrasi disebabkan oleh adanya AWLR yang memiliki pengurangan debit dalam daerah tangkapan air dimana terdapat bangunan pengambilan air (bendung, embung maupun bendungan) yang disadap melalui sungai.
"In the Studio" with William Kentridge
Authors: Mihailovich-Dickman Vera Françoise
Published: September 2023

Abstract Abstract This interview attempts to explore both the individual and collective creative processes of the prolific and world-renowned multiple media visual and performance artist, William Kentridge. It takes place in Paris where the artist has under 30 minutes to engage in a dialogue before the very first performance of his Chamber opera, Sybil, in a theatre new to the troupe. The conversation takes place backstage in the green room, but the dialogue is engaged in a complicit and playful manner, drawing on common backgrounds and histories to cut corners and spare formalities.The result is a new angle on what “Studioness” has become for the artist, although he had never really considered it that way. Exploring the inward-looking and outward-reaching movements within studio practice, the author seeks to enlarge the notion of studio to include remote and virtual practices in the reflection. The impact of, and response to, the COVID-19 lockdown period is central to the discussion.
Construction of Pilgrim Framework-Information Seeking Based on New Norm Selection Criteria of Hajj
Authors: Mat Yatin Saiful Farik , Mohamed Azlinah , Sakri Sapiah , Muhammad Zain Zuhaira , Mohamad Zain Jasni , Shaiba Hadil , Mohammad Alturki Nazik , Aldehim Ghadah Nasser
Published: September 2023

The pilgrimage quota for each country is 0.1% of the total population. The demand to perform Hajj increases yearly and demands more quotas, but it is limited due to providing exemplary services and maintaining comfort for pilgrims. The selection process is challenging and informative. Upon registration, the Malaysian waiting period was between 89 and 116 years. With COVID-19 and the new norm, the waiting period will be much longer, making things worse and more ridiculous. This paper explains and proposes constructing a proper framework for fulfilling the need and selecting future candidates for Hajj in Malaysia.
Online Savings Scheme for An Integrated Qurban (STIQDAT) in Post-COVID-19
Authors: Kamaruddin Noor Hafiz , Mat Yatin Saiful Farik , Mohd Razuki1,2 Mohd Aliff
Published: September 2023

This article analyses the Online Savings Scheme for Qurban (STIQDAT) through the executed model performed by the Selangor Mosques Youth Association in response to the economic challenges because of the post-COVID-19 pandemic. Results show that STIQDAT, which comprises 3 main modules, the Management of Qurban Savings Module, Management of Qurban Distribution Module, and Management of Qurban Supply Module, has vast opportunities and potential to overcome the challenges faced by the nation’s youth because of the pandemic. It offers vast data to be explored and analysed for Malaysian planning for socio-economic growth.
Bioplaguicida Erytec®: Alternativa biológica para el control del gusano cachón Erinnyis ello en los cultivos de caucho y yuca
Authors: Gómez Valderrama Juliana Andrea , Cuartas Otálora Paola Emilia , León Martínez Guillermo Adolfo , Quiroga Cubides Ginna Milena
Published: September 2023

Los cambios en las tendencias de consumo, las ventajas competitivas de estas estrategias de manejo, las nuevas regulaciones y los planes gubernamentales han llevado a que cada vez más productores incorporen estas medidas de control dentro de sus esquemas de manejo de plagas y enfermedades. Por lo anterior, la Corporación Colombiana de Investigación Agropecuaria (AGROSAVIA), desde 2008, ha trabajado en el desarrollo y registro del bioplaguicida Erytec® para el manejo del principal insecto plaga de los cultivos de caucho y yuca en América tropical y Colombia, conocido comúnmente como gusano cachón [Erinnyis ello (Lepidoptera:Sphingidae)]. Este bioplaguicida se desarrolló a partir de un aislamiento nativo de granulovirus colectado en el departamento del Meta, Colombia, y presenta una formulación de alta calidad que le confiere ventajas técnicas para el control de la plaga y su uso en estos sistemas productivos.
Democratizing Artificial Intelligence Imaging Analysis With Automated Machine Learning: Tutorial
Authors: Thirunavukarasu Arun James , Elangovan Kabilan , Gutierrez Laura , Li Yong , Tan Iris , Keane Pearse A , Korot Edward , Ting Daniel Shu Wei
Published: September 2023

Deep learning–based clinical imaging analysis underlies diagnostic artificial intelligence (AI) models, which can match or even exceed the performance of clinical experts, having the potential to revolutionize clinical practice. A wide variety of automated machine learning (autoML) platforms lower the technical barrier to entry to deep learning, extending AI capabilities to clinicians with limited technical expertise, and even autonomous foundation models such as multimodal large language models. Here, we provide a technical overview of autoML with descriptions of how autoML may be applied in education, research, and clinical practice. Each stage of the process of conducting an autoML project is outlined, with an emphasis on ethical and technical best practices. Specifically, data acquisition, data partitioning, model training, model validation, analysis, and model deployment are considered. The strengths and limitations of available code-free, code-minimal, and code-intensive autoML platforms are considered. AutoML has great potential to democratize AI in medicine, improving AI literacy by enabling “hands-on” education. AutoML may serve as a useful adjunct in research by facilitating rapid testing and benchmarking before significant computational resources are committed. AutoML may also be applied in clinical contexts, provided regulatory requirements are met. The abstraction by autoML of arduous aspects of AI engineering promotes prioritization of data set curation, supporting the transition from conventional model-driven approaches to data-centric development. To fulfill its potential, clinicians must be educated on how to apply these technologies ethically, rigorously, and effectively; this tutorial represents a comprehensive summary of relevant considerations.
A Quantum Particle Swarm Optimization Algorithm Based on Aggregation Perturbation
Authors: Wang H. D. , Zhang C. N. , Zhang H. , Wei Y. C. , Guan X. L.
Published: September 2023

A quantum particle swarm hybrid optimization algorithm based on aggregation disturbance is proposed for inventory cost control. This algorithm integrates the K-means algorithm on the basis of traditional particle swarm optimization, recalculates the clustering center, initializes stagnant particles, and solves the problem of particle aggregation. Introducing chaos mechanism into the algorithm, changing the position of particles, enhancing their activity, and improving the algorithm's global optimization ability. At the same time, define the aggregation disturbance factor, determine the current state of particles, optimize speed and position to accelerate escape, and solve the problem of particles falling into local optima. Experiments show that M-IKPSO algorithm has strong stability, fast Rate of convergence and high accuracy compared with other algorithms, and the improvement effect is significant.
The Influence and Fusion of Online Films with Traditional Cinema: A Case Study of the Netflix Platform
Authors: Liu Anran
Published: September 2023

The emergence and popularization of streaming movies have witnessed the change in acceptance mode and acceptance psychology of traditional movie and television, and broke the confinement of time and space. Taking Netflix, a streaming online platform, as a case study, this research endeavors to explore the impact of streaming movies on traditional cinema movies and their convergence utilizing literature analysis, classification and comparative analysis, case study research method, and data collection and analysis method.
Research on the Main Features of D. H. Lawrence’s Poetic Language
Authors: Wang Dong
Published: September 2023

D. H. Lawrence’s poetic language needs to become an important research field and arouse researchers’ attention. Being able to explain profound things in a simple way and arouse strong resonance of readers and enlighten people is one of the main features of Lawrence’s poetic language. Rhyme plays an important role in enhancing the musical effect so as to make a poem impressive. Combining sense of rhythm with musical beauty to make the readers immersed into the feelings that a poem tries to present is an important feature of Lawrence’s poetic language. Lawrence wrote many free verse poems. Free verse with hidden rhythms determined by hidden emotional pattern is a distinctive feature of Lawrence’s poetic language.
On Supply-Side Inflation and Some Unconventional Indicators for Measuring Inflation
Authors: Charaia Vakhtang , Papava Vladimer
Published: September 2023

The paper provides an analysis of the inflation problem caused by the COVID-19 pandemic and continued by Russia’s war against Ukraine, through different channels, including global supply chain disruption, increased governmental spending, decreased supply of goods and, etc. Inflation, which in this case was supply-side driven inflation, caused serious debates in terms of how to tackle the challenge. Should central banks use their standard instruments and is it enough to use the old-fashioned inflation index to create an economic recovery and anti-inflationary policies for different countries, especially when speaking about import-dependent, consumer-style developing countries? Herein, we analyze the most recent challenges of the inflationary process, starting from the point of how it launched and finishing with the issue of how to overcome this current crisis. Some unconventional macroeconomic indicators are also offered for governments and central banks for a better and more in-depth understanding of inflation and for the creation of better policy vis-à-vis inflation.
«Калмыцкая» коллекция из фондов Новочеркасского музея истории Донского казачества
Authors:   Kalmyk Scientific Center of the RAS (8, Ilishkin St., 358000 Elista, Russian Federation), Muchaeva Irina I.
Published: September 2023

Introduction. The article analyzes artifacts largely identified as Buddhist cult objects constituting an individual collection at Novocherkassk Museum of Don Cossack History. Goals. The paper aims to investigate the items of the ‘Kalmyk’ collection and introduce a complete list of the latter into scientific circulation for further expert analyses. Results. The study reveals some inaccuracies in museum labels and suggests new attribution details thereto. The ‘Kalmyk’ collection at Novocherkassk Museum of Don Cossack History is distinguished by that its pieces share somewhat common origin, and are directly related to Don Kalmyk Cossacks whose military service did leave its traces on the artifacts. The collection needs further detailed insights how it actually took shape, and a number of items require further attribution efforts since it is still unclear where and when they came from.