bluuebunny/crossref_metadata_2025 huggingface dataset:
Qualificação profissional na administração pública: uma análise da percepção dos técnicos administrativos do CFP/UFCG
Authors: Freitas Maria do Carmo Rodrigues , Pederneiras Marcleide Maria
Published: January 2020

A pesquisa teve como objetivo principal identificar como os servidores do CFP/UFCG percebe a qualificação com o foco no desenvolvimento de conhecimentos e experiências para atuar em suas funções na busca de uma maior eficiência no serviço prestado dentro do campus de Cajazeiras. A pesquisa realizou-se nas Unidades Administrativas - CFP/UFCG, Campus de Cajazeiras, Campus de Cajazeiras. Para coleta de dados utilizou-se questionário estruturado, Os dados foram agrupados, tabulados e analisados através da estatística descritiva com o auxílio do programa Microsoft® Excel. Como resultados: Os servidores técnico-administrativos do Campus de Cajazeiras-Paraíba, defendem a necessidade constante de atualização para o trabalho, frente às exigências tão dinâmicas hoje em termos de demandas profissionais. Por isso, a qualificação aparece para todos como uma necessidade, mas também como um direito, como o indispensável elemento provedor de qualidade no trabalho, na medida em que busca as respostas para os problemas do dia-a-dia, de forma a apresentar um trabalho mais eficiente e competente.
Marketing Analysis of Bitti Wood (Vitex cofassus) in Bulukumba District, South Sulawesi
Authors: Hayati Nur , Bisjoe Achmad Rizal Hak , Wakka Abdul Kadir
Published: January 2020

Bitti wood (Vitex cofassus) harvested from the private forest has a considerable potential to be developed to fulfill the demand of the local and industrial markets, such as to support the Phinisi boat industries. One important factor in supporting the development and utilization of the bitti’s private timber is its marketing system. This study aimeds to describe the profile of bitti wood marketing and analyze it in supporting the Phinisi boat industries in Bulukumba district. Data collection was carried out through observation and interview several parties involved in the marketing process of bitti by using an interview guide (questionnaire). The results showed that bitti wood marketing actors in Bulukumba District included farmers, middlemen, and the Phinisi industries. There were two patterns of bitti wood marketing at the study site, i.e. the pattern I: Farmers à Phinisi industries and pattern II: Farmers à Middlemen àPhinisi industries. The lowest profit share was received by bitti farmers in the pattern I was about 31,6% and pattern II was about 29,5%, which does not fairly reflect their contribution. To maintain the sustainability of bitti private timber, there is a need to develop a more efficient bitti marketing process from upstream to downstream.
Simulation of Winter Durum Wheat Flour Yield Based on Structural Equation Modeling
Authors: Liu Jianchao , Fu Yuhang , Wang Hangjun , Peng Zhanglin , Fan Xingfuo , Weng Yun , Yao Wenbin
Published: January 2020

Flour yield determined the profitability of flour mill, but the intrinsic variability of the grain makes it very complex to analysis and estimate wheat grain flour yield. Simulation for flour yield attributes offer considerable advantages in flour mill, if reliable predictions of flour yield can be provided, because the wheat grain characteristics can be tested before milling. If this is possible, the characteristics thus observed could be quantified more reliably and objectively by Structural Equation Modelling (SEM). SEM was used to look for the most important wheat grain characteristics on flour yield, and then these wheat grain characteristics were used to simulate flour yield. Furthermore, the regressive equation was verified by the field experiment. The coefficient of variation of grain characteristics was low and distributed rather closely. The results of SEM showed that test weight had the most significantly effects on flour yield, followed by the hardness index. Test weight and hardness index could excellently estimate flour yield by multiplicative effect of test weight and hardness index, and which could determine 68% of the variation in flour yield. The simulation result can not only predict flour yield, but also look for the important grain characteristics for the flour yield.
A Tri-band Low-noise Cryogenic Receiver for Geodetic VLBI Observations with VGOS Radio Telescopes
Authors: López-Pérez José A. , Tercero-Martínez Félix , Serna-Puente José M. , Vaquero-Jiménez Beatriz , Patino-Esteban María , García-Carreño Pablo , González-García Javier , García-Pérez Óscar , Beltrán-Martínez Francisco J. , Albo-Castaño Carlos , Gallego-Puyol Juan D. , López-Fernández Isaac , Díez-González Carmen , Malo-Gómez Inmaculada , Barbas-Calvo Laura , de Vicente-Abad Pablo , López-Fernández José A.
Published: January 2020

This paper shows the development of a simultaneous tri-band (S: 2.2 - 2.7 GHz, X: 7.5 - 9 GHz and Ka: 28 - 33 GHz) low-noise cryogenic receiver for geodetic Very Long Baseline Interferometry (geo-VLBI) which has been developed by the technical staff of Yebes Observatory (IGN) laboratories in Spain. The receiver was installed in the first radio telescope of the Red Atlántica de Estaciones Geodinámicas y Espaciales (RAEGE) project, which is located in Yebes Observatory, in the frame of the VLBI Global Observing System (VGOS). After this, the receiver was borrowed by the Norwegian Mapping Autorithy (NMA) for the commissioning of two VGOS radiotelescopes in Svalbard (Norway). A second identical receiver was built for the Ishioka VGOS station of the Geospatial Information Authority (GSI) of Japan, and a third one for the second RAEGE VGOS station, located in Santa María (Açores Archipelago, Portugal). The average receiver noise temperatures are 21, 23 and 25 Kelvin and the measured antenna efficiencies are 70%, 75% and 60% in S-band, X-band and Ka-band, respectively.
Angiotensin Receptor II type 1 and the activation of Myosin Light-Chain Kinase and Protein Kinase C-βII. Mini Review.
Authors: Smith Gerry A.
Published: January 2020

The involvement of the angiotensin II type 1 receptor in the Frank-Starling Law of the Heart, where the various activations are very limited, allows simple analysis of the kinase systems involved and thence extrapolation of the mechanism to that of angiotensin control of activation of cardiac and skeletal muscle contraction. The involvement of phosphorylation of the myosin light chain in the control of contraction is accepted but not fully understood. The involvement of troponin-I phosphorylation is also indicated but of unknown mechanism. There is no known signal for activation of myosin light chain kinase or Protein Kinase C-βII other than Ca2+/calmodulin but the former is constitutively active and thus has to be under control of a regulated inhibitor the latter kinase may also be the same. Ca2+/calmodulin is not activated in Frank-Starling, i.e. there are no diastolic or systolic [Ca2+] changes. I suggest here that that the regulated inhibition is by myosin light chain phosphatase and/or β-arrestin. Angiotensin activation is by translocation of the β-arrestin from the sarcoplasm to the PM thus reducing its inhibition in the sarcoplasm, this reduced inhibition has been wrongly attributed to a mythical downstream agonist property of β-arrestin.
Of Fire and Smoke Plumes, Polarimetric Characteristics
Authors: Zrnic Dusan , Zhang Pengfei , Melnikov Valery , Mirkovic Djordje
Published: January 2020

Weather surveillance radars routinely detect smoke of various origin. Of particular significance to the meteorological community are wildfires in forests and/or prairies. For example, one responsibility of the National Weather Service in the USA is to forecast fire outlooks as well as to monitor wild fire evolution. Polarimetric variables have enabled relatively easy recognitions of smoke plumes in data fields of weather radars. Presented here are the fields of these variables from smoke plumes caused by grass fire, brush fire, and forest fire. Histograms of polarimetric data from plumes contrast these three cases. Most of the data are from the polarimetric Weather Surveillance Radar 1988 Doppler (WSR-88D aka Nexrad, 10 cm wavelength) hence the wavelength does not influence these comparisons. Nevertheless, in one case simultaneous observations of a plume by the operational Terminal Doppler Weather Radar (TDWR, 5 cm wavelength) and a WSR-88D is used to infer backscattering characteristic and hence sizes of dominant contributors to the returns. In addition, comparisons with observations by other investigators of plumes from urban area but at a 5 cm wavelength are made. To interpret some measurements Computational Electromagnetics (CEM) tools are applied.
Teacher Professionalism and Curricular Change - the Tension between Governance, Control and Professionalism in School
Authors: Hovdenak Sylvi S. , Wiese Eline F.
Published: January 2020

Through looking at the process of Norwegian curricular change from the 1990’s reforms till today, we discuss how the different curricula in different ways affect the possibilities teachers have to act as professional agents in the classroom. Using Bernstein’s concept of the pedagogical discourse and how knowledge produced at the micro level, the level of pedagogical research and practice, we discuss how knowledge gets transformed and recontextualised as it becomes part of the curriculum, the ‘official field’ in Bernstein’s terms, and instead acts as mechanisms for controlling the teachers’ practices. In this paper we argue that curricular change affects the teachers’ potential for professional and autonomous action in the classroom. Furthermore, we point to the implications this has for teacher education, and the need for giving the students the competency to transcend and critically act and reflect on the implications the curricula have for their future teacher professionalism.
Instituintes Culturais da Experiência Curricular-Formativa: Bases Teóricas para um Etnocurrículo
Authors: Macedo Roberto Sidnei , Guerra Denise
Published: January 2020

O presente artigo apresenta um conjunto de conceitos e argumentos entendidos como instituintes culturais da experiência curricular-formativa. Tem como o objetivo central, criar bases argumentativas para um etnocurrículo. Tendo como centralidade teórica a etnometodologia, as experiências e experimentações do Grupo de Pesquisa FORMACCE, seus estudos, pesquisas e intervenções em currículo e formação, o texto caminha no sentido de consolidar o conceito de etnocurrículo, suas bases teóricas e ressonâncias compreensivas. Argumenta, ademais, sobre possibilidades de pesquisa com etnocurrículos a partir de um conjunto de experiências que o FORMACCE vem implementando através da singularidade das suas ações nos campos do currículo e da formação e do seu irredutível entretecimento. Neste contexto argumentativo e conceitual, não se realiza no artigo em pauta apenas um exercício teórico para fundamentar uma conceitua- ção, surge desse esforço uma criação em forma de um dispositivo político em que a centralidade é o interesse social e culturalmente presente de se trabalhar-com a diferença nos âmbitos das questões curriculares e formativas.
Transgredir para Empoderar - O Empoderamento das Jovens Mulheres pela Educação
Authors: Rodrigues Liliana
Published: January 2020

Este trabalho é a base científica, e também podemos dizer, ideológica, de um relatório solicitado pelo Parlamento Europeu à Comissão dos Direitos das Mulheres e da Igualdade dos Géneros que pretende assegurar uma educação democrática e a educação para a igualdade dos géneros. Em Setembro de 2015 este relatório foi aprovado como resolução por uma larga maioria parlamentar, apoiando a ideia da educação e do currículo como instrumentos de poder. Acredito que a educação tem um papel fundamental na mudança e que éresponsável pelo desenvolvimento da personalidade e pela criação de ideias que determinam atitudes, acções e perspectivas sobre o mundo, guiando-nos na vida pessoal e influenciando as escolhas profissionais. Este trabalho foi o primeiro momento de reflexão sobre esta questão e mostra o importante papel da investigação em educação e do currículo no âmbito das políticas europeias.
Non-Affirmative Curriculum Theory in a Cosmopolitan Era?
Authors: Uljens Michael
Published: January 2020

National curriculum making and curriculum theory are challenged by globally growing political, economic and technological interdependencies, transnational homogenization and aggregation processes. In addition increasing pluralisms within nation states present new topics to be solved. These issues are not new from an education theory perspective. A task and contribution in modern education has been a concept explaining how e.g. socialization (social cohesion) and personalization (individuation) may be considered as integrated ratherthan excluding processes. The modern, or classic, approach early identified dilemmas connected to a reproduction- and transformation oriented curricula, as well as dilemmas emanating from descriptive-technological and normative theory. This article elaborates on relational core concepts developed in nineteenth century modern education theory (Fichte, Hegel, Schleiermacher,Herbart, Snellman). Utilizing concepts from modern education theory a non-affirmative position is argued for as an answer to parts of contemporary challenges.
O (pós) crítico na Desconstrução Curricular
Authors: Pacheco José Augusto , Sousa Joana
Published: January 2020

Como em todos os campos do conhecimento das ciências humanas e sociais, a educação tem sido confrontada com perspetivas epistemológicas ligadas à teorização crítica e com novas discussões introduzidas pelas análises pós. Entende-se, neste artigo, que, em termos conceptuais, as teorias crítica e pós-crítica existem numa multiplicidade de abordagens e que as suas diferenças se inscrevem em redes conceptuais de discursos e práticas que têm aspetos em comum, mesmo que, por vezes, pareçam antagónicas. Atualmente, nos estudos curriculares, a sua discussão tende a fazer-se em torno do conhecimento num quadro de políticas curricularesdistintas, umas orientadas pelo legado universal das disciplinas, outras baseadas em argumentos que valorizam a subjetividade.
Jogos Didáticos como Recursos Complementares para o EnsinoAprendizagem de Química
Authors: Cunha Ana Paula de Araujo , Zimmer Rosana
Published: January 2020

O presente artigo é resultante de uma pesquisação, que compreendeu a construção e o uso de jogos como recursos didático-pedagógicos complementares para o ensino de conteúdos específicos de Química. O estudo foi desenvolvido com alunos de turmas do Ensino Mé- dio, de uma escola pública localizada na região serrana do Rio Grande do Sul, na qual uma das pesquisadoras- -autoras leciona. A justificativa pela escolha deste tema respalda-se na necessidade de investigar formas de promover, de modo mais efetivo, a aprendizagem de conteúdos em contexto de sala de aula, partindo do pressuposto de que, quando os estudantes estão ativamente envolvidos na tarefa, esses aprendem mais do que quando são meros “recipientes” de instrução (MURCIA, 2005; SMOLE, 2007).
Knowledge and Power in the São Francisco River Basin Committee
Authors: Netto Antenor de Oliveira Aguiar , Costa Patricia Rosalba Salvador Moura , Oliveira Hannah Uruga
Published: January 2020

This article aims to analyze the speeches that constitute the records relating to plenary meetings of River Basin Commission of the São Francisco River (CBHSF), centered on the timeframe of December 2002 to December 2007. Methods insert in documentary sources of analysis relying theoretically the concept of a historically marked document and revealing power-knowledge relations (FOUCAULT, 2009). As a result, we point out that the installation of the basin Committee is configured as a space knowledge and power, in which the members elected, when it has the technical and educational domain, now have an important role in decisions involving the waters of this important river.
Ensaio sobre a História e Cultura Afro-Brasileira e Indígena Trabalhadas nas Salas de Aulas do Ensino Fundamental das Escolas Públicas no Nordeste do Brasil: Entre Desafios dos Livros Didáticos e Docência
Authors: Souza Lucas Colangeli de , Di Gregório Maria de Fátima
Published: January 2020

Esta pesquisa objetiva investigar como a história e cultura afro-brasileira e indígena são trabalhadas nas salas de aulas do ensino fundamental em escolas públicas no Nordeste do Brasil, em seus desafios entre ambientes escolares e docência, cujos conteúdos expressos nos livros didáticos utilizados nas salas de aulas ainda têm incutido uma ideologia subjacente de um processo de marcas quanto à questão da família indígena – resquícios nos processos hegemônicos de colonização do país, evidenciando especificamente o papel da mulher indígena na sociedade brasileira, porta aberta para pensar como os professores têm lidado com a complexa questão da identidade desse grupo. Através de um modo de pensar hermenêutico, busca-se compreender os saberes construídos a partir dessas informações que se estruturam, diante da historiografia da mulher indígena nos processos de colonização, na sociedade e a mentalidade que transpôs marcas através de gerações
La Educación Sexual en el Sistema Educativo Formal Costarricense
Authors: Preinfalk-Fernández María Luisa
Published: January 2020

El presente artículo tiene como propósito mostrar a grandes rasgos el proceso histórico-evolutivo de la educación sexual en el sistema educativo costarricense. Se elabora un recorrido por los principales hitos acaecidos a partir de los años sesenta hasta la actualidad, enfatizando en las políticas y programas estatales vigentes, sus enfoques, ejes y contenidos. Se trata de una historia caracterizada por avances y retrocesos, intereses y luchas políticas e ideológicas en la que se desvela el rol y carácter del Estado, que transita desde una figura de apoyador hasta el de protagonismo y gestor de la política pública. El papel del Estado en la educación sexual ha influenciado un enfoque biologicista de la sexualidad, de carácter informativo y mediado por preceptos religiosos, que repercute en una población joven carente de conocimientos y habilidades para vivir una sexualidad segura, placentera y libre de violencia, y en un cuerpo docente que no está preparado para poner en práctica en las aulas los nuevos enfoques que se demandan.
Moradas para el más allá. Élites rurales y fundaciones funerarias en época moderna: Lucena, siglos XVI al XVIII
Authors: Serrano Márquez Nereida
Published: January 2020

Este trabajo analiza una de las vías más recurrentes de promoción de arquitectura sacra por parte de las élites rurales en la Andalucía moderna: las capillas funerarias en templos conventuales y parroquiales. Tomando como escenario la ciudad de Lucena, capital del estado de Comares, se aborda la proyección de tales fundaciones desde sus múltiples aristas: la espiritual, la artística y simbólica, y la socioeconómica, que recibe un más amplio tratamiento al conectar el acceso a ellas y su proliferación con los procesos de venalidad y mercantilización de sepulturas
Genetic Diversity Analysis of 14 Potato Genotypes Based on Morphological Characters and SSR Markers
Authors: Nugroho Kristianto , Terriyana Rerenstradika T. , Kusmana Kusmana , Lestari Puji , Tasma I Made
Published: January 2020

Potato is one of important carbohydrate sources used as an alternative crop in Indonesia. The challenges in national potato breeding program included low productivity, less tolerance to environmental stresses, and narrow genetic diversity. The purpose of this study was to analyze genetic diversity of 14 potato genotypes based on morphological characters and SSR
markers newly developed from genome sequences of Indonesian potato genotypes. Principal component analysis of morphological data was done using program XLSTAT. DNA of 14 potato genotypes were assayed using 22 SSR markers. Phylogenetic tree was constructed using program NTSYS version 2.1. The PCA showed that leaf shape, leaf color, tuber shape,
tuber skin color, and tuber color contributed most to the total diversity. SSR polymorphism analysis demonstrated that as many as 196 alleles were detected in this study. The average allele number was 8.9 ranged from 5 to 13 alleles per locus. The average major allele frequencies was 22% ranged from 14 to 43%. Gene diversity ranged from 0.70 to 0.92 with the average of 0.86, meanwhile the heterozigosity observed ranged from 0 to 0.71 with the average of 0.05. Phylogenetic analysis generated two main clusters in the coefficient of similarity 0.77. The first cluster consisted of three genotypes while the second cluster consisted of eleven genotypes. The new developed SSR markers used in this study were able to differentiate potato accessions having similar morphological characters but were different genetically. The results of this study should be useful in assessing
genetic materials in potato cultivar development program.
Genetic Diversity Analysis of 41 Chili Pepper Genotypes [Capsicum annuum L.] Based on SSR Markers
Authors: Wartono Wartono , Wiyono Suryo , Syukur Muhamad , Giyanto Giyanto , Nugroho Kristianto , Lestari Puji
Published: January 2020

Chili (Capsicum annuum L.) is an important horticultural crop which possesses high genetic diversity. Their genetic diversity needs to be assessed through molecular marker-based analysis to facilitate chili breeding scheme. The objective of the study was to analyze the genetic diversity of 41 chili genotypes using Simple Sequence Repeat (SSR) markers. Eleven SSR markers were used to amplify all genotypes through PCR technique, visualized on Polyacrylamide Gel Electrophoresis (PAGE). The data were analyzed using NTSYSpc version 2.1 and PowerMarker version 3.25 softwares. Results showed that the average of
SSR alleles was 7.9 with a range of 4-11 alleles per marker. All SSR markers showed PIC value >0.5, indicating their suitable use for chili genetic studies. Cluster analysis of 41 genotypes generated three main groups according to coefficient similarity of 77.4%. The genetic clusters appeared as reflection of the genetic background of each genotype. In addition, the SSR markers used can identify potential parent as indicated by the genetic distance between genotypes. The highest genetic diversity (0.698) was demonstrated by combinations of Yuni × Ayesha, Yuni × Ayesha 2, and Yuni × Namira. The estimated genetic diversity produced by SSR markers in this study should be useful as guidance for chili breeders to select suitable parents for new cultivar development for high productivity and resistance to diseases.
Molecular Analysis and Phenotypic Performances of BC3F2 Upland Rice Lines Containing Alt and Pup1 Loci
Authors: Mizan Muhammad Rauful , Wirnas Desta , Tasliah NFN , Hidayatun Nurul , Prasetiyono, S.P., M.Si. Joko
Published: January 2020

The challenges in upland rice cultivation are phosphorous (P) deficiency and aluminum (Al) toxicity, each controlled by Pup1 and Alt loci, respectively. Pyramiding the two genes into Indonesian rice varieties were previously done through Marker-Assisted Backcrossing method to obtain BC3F2 populations. The aims of this study were to analyze the BC3F2 upland rice lines containing the Alt and Pup1 loci molecularly (foreground and background analyses) and to test their phenotypic performances. Genetic materials tested included Dupa variety (donor of Alt) and three improved Indonesian genotypes (Dodokan-Pup1, Situ Bagendit-Pup1, and Batur-Pup1) as recurrent parents, Kasalath (donor of Pup1), and 300 BC3F2 lines from Dodokan-Pup1+Alt, Situ Bagendit-Pup1+Alt, and Batur-Pup1+Alt, respectively. The rice genotypes were selected individually using modified Yoshida nutrient solution, followed by foreground and background analyses. 150 out of 300 seedlings were selected and maintained until harvest in the greenhouse. Foreground analysis using markers (RM1361, RM12031, and Kas46-2) and tiller number performances resulted in 18 plants from BC3F2 Dodokan-Pup1+Alt, 30 plants from BC3F2 Situ Bagendit-Pup1+Alt, and 25 plants from BC3F2 Batur-Pup1+Alt still carrying Alt and Pup1 loci. Background analysis using molecular markers showed that the best individual lines of BC3F2 were number 56 for BC3F2 Dodokan-Pup1+Alt, number 32 or 70 for BC3F2 Situ Bagendit-Pup1+Alt, and number 20 for BC3F2 Batur-Pup1+Alt. The selected lines having both both Alt and Pup1 loci in homozygote condition with highest number of tiller per plant which are useful genetic materials for developing upland rice variety tolerance to low P and Al toxicity.
EFFECTS OF GOVERNANCE MEDIATION ON THE RELATIONSHIP BETWEEN ENTERPRISE RISK MANAGEMENT AND FINANCIAL PERFORMANCE
Authors: Nurhayati -
Published: January 2020

This study explains the effects of mediating the role of university governance elements on the relationship between implementation of ERM and financial performance. The background of this research is inconsistency in prior studies and the phenomenon of low accountability at universities and the existence of low internal control function.  Based on the final report of Supervision, Control and Development (WASDALBIN) for the period of 2016 indicates that private universities not accredited yet are 52%. The data collection techniques applied survey methods and the data analysis techniques used Structural Equation Modeling (SEM) PLS. The results show that ERM significantly affect financial performance through the role of university governance elements.
ANALISIS PERENCANAAN BAHAN AJAR TEMATIK BERBASIS KEARIFAN LOKAL PADA MAHASISWA PGSD
Authors: Utami Ima Wahyu Putri , Suwandayani Beti Istanti
Published: January 2020

Tujuan penelitian ini untuk menganalisis penyusunan perencanaan pembelajaran tematik berbasis kearifan lokal mahasiswa PGSD dan juga mendeskripsikan faktor pendukung dan penghambat serta menganalisis upaya yang dilakukan dalam mengatasi hambatan dalam penyusunan perencanaan tersebut. Penelitian ini merupakan penelitian kualitatif dengan menggunakan teknik pengumpulan data yaitu observasi, wawancara dan dokumentasi. Hasil penelitian tersebut menunjukkan bahwa mahasiswa menyusun rancangan pembelajaran menyesuaikan dengan kearifan lokal daerah masing-masing. Faktor penghambatnya adalah mahasiswa masih kurang mendalam dalam pengembangan indikator dan memilih model pembelajaran yang sesuai dengan materi kearifan lokal. Faktor pendukungnya adalah pengetahuan mahasiswa tentang kearifan lokal yang ada di daerah masing-masing memperkaya materi bahan ajar.
Effects of Moving Cupping Therapy for Plaque Psoriasis: A Protocol for a Randomised Multicentre Clinical Trial
Authors: Xing Meng , Yan Xiaoning , Yang Suqing , Li Linge , Gong Liping , Liu Hongxia , Xu Rong , Chen Jie , Ying Luo , Zhao Yiding , An Yuepeng , Liu Yang , Huang Gang , Guo Fei , Yin Qingfeng , Wang Ruiping , Li Bin , Li Xin
Published: January 2020

Background: The clinical treatment of plaque psoriasis is based on comprehensive therapy, which is expensive and unsatisfactory, and some of the drugs currently used have serious side effects. Moving cupping therapy has been used clinically for thousands of years in China and has the advantage of being inexpensive and easy to perform. It is now widely used in public hospitals in China for the treatment of psoriasis. However, at present, a comprehensive evaluation of the current clinical evidence regarding its use is lacking. This study aims to evaluate the efficacy and safety of moving cupping in the treatment of plaque psoriasis. Methods and analysis: A multicentre, two-arm parallel group, single-blind randomised controlled trial will be conducted in six academic and non-academic hospitals in China. A total of 110 adult patients (aged 18-65 years) who meet the inclusion criteria are now being recruited. Participants will receive (1) basic treatment combined with moving cupping therapy or (2) basic treatment combined with moving cupping placebo. The treatment cycle will be 4 weeks, and the treatment efficacy will be assessed weekly using the Psoriasis Area and Severity Index during the treatment period and the follow-up visits at weeks 6 and 8. The body surface area, physician's global assessment, Dermatology Life Quality Index, patient-reported quality of life, visual analogy scale, traditional Chinese medication syndrome scoring scale, combined medication, and adverse events will also be recorded and compared to the baseline values. Discussion: The results of this trial may help make better decisions in the treatment of plaque psoriasis. If the results are considered to be favorable, this ancient Chinese medicine therapy may be worthier of promotion because of its convenience and cheap advantages to benefit patients. Trial registration: This study has been registered at ClinicalTrials.gov under the identifier number NCT03952676. Registered on 15 May 2019.
Women’s knowledge of and attitudes toward cervical cancer and cervical cancer screening in Zanzibar, Tanzania: a cross-sectional study
Authors: Weng Qiao , Jiang Jie , Haji Fatma Mrisho , Nondo Lamlet Hassan , Zhou Huaijun
Published: January 2020

Background: Cervical cancer is the most common cancer and the leading cause of cancer death among women in Tanzania. Knowledge of and willingness to receive a cervical cancer screening are important determinants of prevention. This study aimed to describe women's awareness of cervical cancer and to explore the attitudes toward, acceptability of and barriers to cervical cancer screening (CCS) in Zanzibar.

Methods: A cross-sectional study was conducted from March to June 2018 involving 1483 women from 10 districts in Zanzibar who responded to questionnaires concerning their general demo-graphic characteristics, screening willingness and awareness of cervical cancer. Chi-square tests, analysis of variance (ANOVA) and stepwise multiple regression were conducted using STATA 15.1 software.

Results: The average total knowledge score (TKS) was 7.84±5.32 on a 23-point scale. Educational level and family income were positively correlated with the TKS. Previous schistosomiasis history and family genetic disease history were strong predictors of screening willingness. Women were less likely to be screened freely if they had 7 or more deliveries and were unaware of any previous family tumor history. Age and educational level were negatively associated non-free screening willingness, while family income was positively associated; being divorced/widowed or single and being unaware of any previous family tumor history were predictors of screening reluctance, while previous disease history was a strong predictor of non-free screening willingness. Fear of screening and inconvenience were the primary concerns among the Zanzibari interviewees. Compared to the 20-49 age group, more women in the less than 20 and 50 or more age groups thought cervical cancer screening was not necessary. The highest rate of cognitive accuracy in regard to cervical cancer warning signs and risk factors was only 37.76%.

Conclusions: The findings revealed that knowledge of cervical cancer was poor. Educational level, family income and awareness of previous disease history were significant influencing factors of screening uptake. Specific awareness programs to increase knowledge of cervical cancer and screening willingness should be designed and implemented in the public without delay, especially for younger and elderly women.

Keywords: Knowledge, Cervical cancer, Screening, Zanzibar
Association Between Water, Sanitation, General Hygiene And Oral Hygiene Practices Of Street Involved Young People In Southwest Nigeria
Authors: Folayan Morenike Oluwatoyin , Obiyan Mary O. , Olaleye Atinuke O.
Published: January 2020

Background: Oral hygiene practices can be linked to personal hygiene practices, including access to water and other sanitation facilities. The objective of the study was to determine if there is an association between oral hygiene practices and water and sanitation hygiene (WASH) practices among street-involved young people (SIYP). Methods: A cross-sectional study involving SIYP age 10-24 years in two states in Nigeria recruited through respondent-driven sampling was conducted in December 2018. Interviewer-administered questionnaires were used to collect data on water access, sanitation, personal and oral hygiene. The instruments used for collecting the data were standardized tools for measuring the phenomena studied. The association between knowledge and practice of oral hygiene; oral hygiene and water, sanitation and hygiene (WASH), and indicators of good oral hygiene were determined using binary logistic regression guided by two models. Results: A total of 845 study participants were recruited. The proportion of SIYP with good knowledge of oral hygiene was low (31.2%), and fewer had good oral hygiene practice (8.9%). There were significant associations between knowledge and practice of tooth cleaning, use of fluoride-containing toothpaste, dental flossing, consumption of sugar between meals, and frequency of dental check-ups (p<0.001 respectively). Respondents with good water collection and storage (AOR: 2.01; 95% CI: 1.24-3.24; P=0.005) and those residing in Lagos (AOR: 2.85; 95% CI: 1.61-5.06; P=0.001) had a higher likelihood of having good oral hygiene. Conclusion: Good oral hygiene practices of SIYP in Nigeria is associated with access to water collection and storage. WASH programs can have an impact on health through improved oral hygiene practices.
Neonatal hand, foot, and mouth disease due to Coxsackievirus A6 in Shanghai
Authors: Xu Shanshan , Li Huajun , Qiao Peng , Xu Guofeng , Zhao Dongying , Lin Xiaoyan , Qin Yu , Yu Huiju , Zhang Xi , Zhang Wanju , Huang Lisu
Published: January 2020

Background: Evidence of hand, foot, and mouth disease (HFMD) in neonates is limited. The aim of this study was to evaluate the clinical symptoms, possible transmission routes, and prognosis of neonatal HFMD in Shanghai.

Methods: This was a case-control study based on the HFMD registry surveillance system. All neonates and infected family members were enrolled between 2016 and 2017 in Shanghai. Neonates with HFMD were followed for at least half a year. Detailed questionnaires, medical history, and physical examination were recorded. Routine blood examination, liver and renal function, immunophenotypes of peripheral blood lymphocytes (CD3, CD4, and CD8 T-cells; NK cells), immunoglobulin (Ig) M, IgG, and IgA, and cytokine interleukin (IL-1β, IL-2R, IL-6, IL-8, IL-10, and TNF-α) levels were measured. All rectal swab specimens were collected and genotyped for enterovirus. T-test or nonparametric test was used to evaluate the differences. Logistic analysis was applied to calculate the risk of clinical symptoms in the group of HFMD neonates and their paired siblings.

Results: There were 16 neonates among the 12608 diagnosed patients with HFMD, accounting for 0.1%. All neonatal infections were transmitted by other members of the family, mainly the elder siblings, and involved different types of coxsackievirus A6. Coxsackievirus A6 is also the emerging and predominant causative agent of HFMD in Shanghai. None of the neonates with HFMD suffered fever, onychomadesis, or severe complications. However, two elder sibling patients showed lethargy, and one developed hypoperfusion. In the elder siblings with HFMD, the proportion of white blood cells was generally higher than in neonates with HFMD. The immunologic function of the neonates with HFMD was basically normal. The levels of inflammatory markers were higher in both neonates and elder siblings with HFMD compared to their age-matched controls. The clinical symptoms receded after about one week of onset. None of the neonates had sequelae.

Conclusions: All neonates with coxsackievirus A6 HFMD had mild disease with no complications or sequelae. Notably, due to the two-child policy in China, elder siblings may be the main route of HFMD transmission.
Integrative analysis of outer membrane vesicles proteomics and whole-cell transcriptome analysis of eravacycline induced Acinetobacter baumannii strains
Authors: Kesavan Dinesh Kumar , Vasudevan Aparna , Wu Liang , Chen Jianguo , Su Zhaoliang , Wang Shengjun , Xu Huaxi
Published: January 2020

Background Acinetobacter baumannii is a multidrug resistant (MDR) hazardous bacterium with very high antimicrobial resistance profiles. Outer membrane vesicles (OMVs) help directly and/or indirectly towards antibiotic resistance in these organisms. The present study aims to look on the proteomic profile of OMV as well as on the bacterial transcriptome upon exposure and induction with eravacycline, a new synthetic fluorocycline. RNA sequencing analysis of whole cell and LC–MS/MS proteomic profiling of OMV proteome abundance were done to identify the differential expression among the eravacycline-induced A. baumannii ATCC 19606 and A. baumannii clinical strain JU0126.Results The Differential expressed genes from the RNA sequencing and were analysed using R package and bioinformatics software and tools. Genes encoding drug efflux and membrane transport were upregulated among the DEGs from both ATCC 19606 and JU0126 strains. As evident with the induction of eravacycline resistance, ribosomal proteins were upregulated in both the strains in the transcriptome profiles and also resistance pumps, such as MFS, RND, MATE and ABC transporters. High expression of stress and survival proteins were predominant in the OMVs proteome with ribosomal proteins, chaperons, OMPs OmpA, Omp38 upregulated in ATCC 19606 strain and ribosomal proteins, toluene tolerance protein, siderophore receptor and peptidases in the JU0126 strain. The induction of resistance to eravacycline was supported by the presence of upregulation of ribosomal proteins, resistance conferring factors and stress proteins in both the strains of A. baumannii ATCC 19606 and JU0126, with the whole-cell gene transcriptome towards both resistance and stress genes while the OMVs proteome enriched more with survival proteins.Conclusion The induction of resistance to eravacycline in the strains were evident with the increased expression of ribosomal and transcription related genes/proteins. Apart from this resistance conferring efflux pumps, outer membrane proteins and stress related proteins were also an essential part of the upregulated DEGs. However, the expression profiles of OMVs proteome in the study was independent with respect to the whole cell RNA expression profiles with low to no correlation. This indicates the possible role of OMVs to be more of back-up additional protection to the existing bacterial cell defence during the antibacterial stress.
Patterns of access to reproductive health services in Ghana and Nigeria: results of a cluster analysis
Authors: Ogundele Oluwasegun Jko , Pavlova Milena , Groot Wim
Published: January 2020

Background To understand differences in access to reproductive healthcare services, the use of family planning and maternal care by women in Ghana and Nigeria is examined.Methods We used population-level data from the Ghana and Nigeria Demographic Health Surveys of 2014 and 2013 in two-step cluster analysis followed by multinomial logistic regression analysis.Results The initial two-step cluster analyses on family planning identify three groups of women in Ghana and Nigeria: women with high, medium and poor access to family planning services. The subsequent two-step cluster analyses identify five distinct groups: higher, high, medium, low and poor access to maternal health services in Ghana and Nigeria. The multinomial logistic regression shows that education and occupation are associated with access to family planning and maternal health services. Women without education often have poor access to reproductive health services in both countries. In Nigeria, household wealth is strongly associated with access to maternal health services but household wealth does not explain access in Ghana. Not having insurance in Ghana is associated with low access to family planning service, while this is not the case in Nigeria.Conclusions These differences confirm the importance of a focused context-specific approach towards reproductive health services, particularly to reduce inequality in access resulting from socioeconomic status.
Population-level investigation of the knowledge of ocular chemical injuries and proper immediate action
Authors: Seraj Hadeel , Khawandanh Shahad , Fatani Arwa , Saeed Afnan , Alotaibi Ghadeer , Basheikh Ahmed
Published: January 2020

Objective: Although the eyes occupy 0.1% of the total body surface, eye injuries are serious because vision is arguably the most important sense. We aimed to assess knowledge of Saudi Arabian residents regarding steps to be taken in cases of chemical eye injury, in order to promote awareness of such procedures. Results: This study included 888 individuals in the Saudi community; most of them were female (624, 70.3%), and 359 (40.4%) respondents were 18–29 years of age. Regarding the first step taken in case of chemical eye injury, 697 (78.5%) respondents indicated washing with water, 164 (18.5%) indicated visiting the emergency department, 11 (1.2%) indicated using eye drops, and 5 (0.6%) indicated covering the eye immediately. A total of 491 (55.3%) respondents agreed that alkaline injuries were more dangerous than acidic injuries. Seventy-five (8.4%) respondents agreed that an eye injured with an acidic material should be washed with an alkaline solution, while 60 (6.8%) respondents agreed that an eye exposed to an alkaline material should be washed with an acidic solution. These results should be confirmed by health authorities and appropriate interventions should be developed for improving perception and knowledge among masses, thereby promoting a healthier society.
Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: A scoping review
Authors: Selveindran Santhani M , Tango Tamara , Khan Muhammad Mukhtar , Simadibrata Daniel Martin , Hutchinson Peter JA , Brayne Carol , Hill Christine , Servadei Franco , Kolias Angelos G , Rubiano Andres M , Joannides Alexis J , Shabani Hamisi K
Published: January 2020

Background Neurotrauma is an important global health problem. The largest cause of neurotrauma worldwide is road traffic collisions (RTCs), particularly in low-and middle-income countries (LMICs). Neurotrauma and RTCs are preventable, and many preventative interventions have been implemented over the last decades, especially in high income countries (HICs). However, it is uncertain if these strategies are applicable globally due to variations in environment, resources, population, culture and infrastructure. Given this issue, this scoping review aims to identify, quantify and describe the evidence on approaches in neurotrauma and RTCs prevention, and ascertain contextual factors that influence their implementation in LMICs and HICs.Methods A systematic search was conducted using five electronic databases (MEDLINE, EMBASE, CINAHL, Global Health EBSCO, Cochrane Database of Systematic Reviews), grey literature databases, government and non-government websites, as well as bibliographic and citation searching of selected articles. The extracted data were presented using figures, tables, and accompanying narrative summaries. The results of this review were reported using the PRISMA Extension for Scoping Reviews (PRISMA-ScR).Results A total of 411 publications met the inclusion criteria, including 349 primary studies and 62 reviews. More than 80 percent of the primary studies were from HICs, and described all levels of neurotrauma prevention. Only 65 papers came from LMICs, which mostly described primary prevention, focussing on road safety. For the reviews, 41 papers (66.1%) reviewed primary, 18 tertiary (29.1%), and three secondary preventative approaches. Most of the primary papers in the reviews came from HICs (67.7%) with 5 reviews on only LMIC papers. Fifteen reviews (24.1%) included papers from both HICs and LMICs. Intervention settings ranged from nation-wide to community-based, but were not reported in 44 papers (10.8%), most of which were reviews. Contextual factors were described in 62 papers, and varied depending on the interventions.Conclusions There is a large quantity of global evidence on strategies and interventions for neurotrauma and RTCs prevention. However, less papers were from LMICs, especially on secondary and tertiary prevention. More primary research needs to be done in these countries to determine what strategies and interventions exist, and the applicability of HIC interventions in LMICs.
Pre-hospital CPR and early REBOA in trauma patients - Results from the ABOTrauma Registry.
Authors: Hilbert-Carius Peter , McGreevy David T , Abu-Zidan Fikri M. , Hörer Tal M.
Published: January 2020

Background: Severely injured trauma patients suffering from traumatic cardiac arrest (TCA) and requiring cardiopulmonary resuscitation (CPR) rarely survive. The role of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) performed early after hospital admission in patients with TCA is not well-defined. As the use of REBOA increases, there is great interest in knowing if there is a survival benefit related to the early use of REBOA after TCA. Using data from the ABOTrauma Registry, we aimed to study the role of REBOA used early after hospital admission in trauma patients who required pre-hospital CPR. Methods: Retrospective and prospective data on the use of REBOA were collected from the ABOTrauma Registry from 11 centers in seven countries globally between 2014 and 2019. In all patients with pre-hospital TCA, the predicted probability of survival, calculated with the Revised Injury Severity Classification II (RISC II), was compared with the observed survival rate. Results: Of 213 patients in the ABOTrauma Registry, 26 patients (12.2%) who had received pre-hospital CPR were identified. The median (range) Injury Severity Score (ISS) was 45.5 (25-75). Fourteen patients (54%) had been admitted to hospital with ongoing CPR. Nine patients (35%) died within the first 24 hours, while seventeen patients (65%) survived post 24 hours. The survival rate to hospital discharge was 27% (n=7). The predicted mortality using the RISC II was 0.977 (25 out of 26). The observed mortality (19 out of 26) was significantly lower than the predicted mortality (p=0.049). Patients not responding to REBOA were more likely to die. Only one (10%) out of 10 non-responders survived. Survival rate in the 16 patients responding to REBOA was 37.5% (n=6). REBOA with a median (range) duration of 45 (8-70) minutes significantly increases blood pressure from median (range) 56.5 (0-147) to 90 (0-200) mmHg. Conclusions: Mortality in patients suffering from TCA and receiving REBOA early after hospital admission is significantly lower than predicted by the RISC II. REBOA may improve survival after TCA. The use of REBOA in these patients should be further investigated. Keywords: REBOA, Cardiac Arrest, Trauma, CPR, Endovascular Resuscitation.