bluuebunny/crossref_metadata_2025 huggingface dataset:
Large Scale Screening of Rhizospheric Allelopathic Bacteria and Their Potential for the Biocontrol of Wheat-Associated Weeds
Authors: Abbas Tasawar , Zahir Zahir Ahmad , Naveed Muhammad , Abbas Sana , Alwahibi Mona S. , Elshikh Mohamed Soliman , Mustafa Adnan
Published: September 2020

Conventional weed control practices have generated serious issues related to the environment and human health. Therefore, there is a demand for the development of alternative techniques for sustainable agriculture. The present study performed a large-scale screening of allelopathic bacteria from the rhizosphere of weeds and wheat to obtain biological weed control inoculants in the cultivation of wheat. Initially, around 400 strains of rhizobacteria were isolated from the rhizosphere of weeds as well as wheat that grows in areas of chronic weed invasions. A series of the screen was performed on these strains, including the release of phytotoxic metabolites, growth inhibition of sensitive Escherichia coli, growth inhibition of indicator plant of lettuce, agar bioassays on five weeds, and agar bioassay on wheat. Firstly, 22.6% (89 strains) of the total strains were cyanogenic, and among the cyanogenic strains, 21.3% (19 strains) were inhibitory to the growth of sensitive E. coli. Then, these 19 strains were tested using lettuce seedling bioassay to show that eight strains suppressed, nine strains promoted, and two strains remained ineffective on the growth. These 19 strains were further applied to weeds and wheat on agar bioassays. The results indicated that dry matter of broad-leaved dock, wild oat, little seed canary grass, and common lambs’ quarter were reduced by eight strains (23.1–68.1%), seven strains (38.5–80.2%), eight strains (16.5–69.4%), and three strains (27.5–50.0%), respectively. Five strains suppressed the growth of wheat, nine strains increased its dry matter (12.8–47.9%), and five remained ineffective. Altogether, the strains that selectively inhibit weeds, while retaining normal growth of wheat, can offer good opportunities for the development of biological weed control in the cultivation of wheat.
Pharmacokinetics and Protective Effects of Tartary Buckwheat Flour Extracts against Ethanol-Induced Liver Injury in Rats
Authors: Jin Hye-Rin , Lee Suyong , Choi Soo-Jin
Published: September 2020

The grains of Tartary buckwheat (Fagopyrum esculentum) are traditionally consumed on a daily basis and are used in the preparation of diverse processed foods owing to the high concentration of rutin, an antioxidant compound. However, rutin is highly concentrated in hull and bran, but not in edible flour fractions. Rutin-enriched TB flour extracts (TBFEs) were obtained by hydrothermal treatment (autoclaving, boiling, or steaming) and their pharmacokinetic profiles were evaluated following a single-dose oral administration in rats. The antioxidant and protective activities of the extracts against alcoholic liver disease (ALD) were investigated after repetitive oral administration of TBFEs for 28 days prior to ethanol ingestion. The results demonstrated that rutin-enriched TBFEs had better oral absorption and was retained longer in the bloodstream than native TBFE or standard rutin. The activities of antioxidant enzymes and intracellular antioxidant levels increased in ALD rats following TBFE treatments, especially following the administration of rutin-enriched TBFEs. The antioxidant activity of TBFEs consequently contributed toward protecting the liver against injury caused by repetitive ethanol administration, as confirmed by analyzing relative liver weight, liver injury markers, lipid peroxidation, and calcium permeability. These results suggest the promising potential of TBFEs as antioxidant-enriched functional foods for human health.
A Novel Comprehensive Method for Modeling and Analysis of Mesh Stiffness of Helical Gear
Authors: Hou Shaoshuai , Wei Jing , Zhang Aiqiang , Zhang Chunpeng , Yan Junhui , Wang Changlu
Published: September 2020

The mesh stiffness of gear pairs used in aerospace applications, such as geared turbofan, has a vital influence on vibration and noise. To compensate for the deficiencies of the conventional method that does not consider slice coupling and structure coupling simultaneously, a comprehensive mathematical model for computing the mesh stiffness of helical gears is established. In this novel model, the effect of structure coupling and slice coupling between neighboring sliced gears are considered. The effect of the axial component of meshing force is also taken into account simultaneously. The results obtained by the comprehensive model are consistent with the finite element method and it proves that the novel mathematical model is sound. The influences of the helical angle and addendum modification coefficient on mesh stiffness are studied. The results show that the mesh stiffness of helical gears would be decreased in multiteeth regions caused by structure coupling. With or without consideration of the axial component, the relative mean values of mesh stiffness become larger with an increasing helical angle. The fluctuation value of mesh stiffness decreases when a positive addendum modification coefficient is adopted. The addendum modification also changes the phase of mesh stiffness. This study is helpful for a vibration analysis of gear transmission systems.
An Experimental Study on Alkali Silica Reaction of Concrete Specimen Using Steel Slag as Aggregate
Authors: Choi So Yeong , Yang Eun Ik
Published: September 2020

In this study, the characteristics of the alkali-silica reaction (ASR) expansion of steel slag itself, mortar bars, and concrete specimens using steel slag as aggregate are individually investigated by the expansion test method, to determine if steel slag aggregate in concrete can provide volume stability. The results show that when steel slag is aged in water for one month, its self-expansibility is below the permitted limit of 1.5% according to the JIS A 5015 standard. The ASR test results show that the ASR expansion of the mortar bars continuously increased with the increase in the test period. However, all mortar bars were below the permitted limit of 0.1% after 14 days according to the ASTM C 1260 standard. In contrast, the ASR expansion of concrete specimens was above the criteria prescribed by the ASTM C 1293 standard. From the results, the expansion of concrete specimens could not be controlled within the permitted limit by the ASTM 1293 criteria, even if the expansivity of steel slag did not exceed the criteria. Meanwhile, considering the crack propagation patterns of the concrete specimens, the cracks due to ASR expansion developed and connected even when the expansion was below the permitted limit. Besides, when mineral admixtures were used as the binder in the concrete specimens, there were discrepancies in the results between the expansion rate and the crack properties, such as maximum length and total crack length. Therefore, to accurately determine the change in volume due to ASR expansion in concrete using steel slag as coarse aggregate, it is necessary to check the crack patterns in addition to evaluating the expansion rate.
Towards Fully Jitterless Applications: Periodic Scheduling in Multiprocessor MCSs Using a Table-Driven Approach
Authors: Capota Eugenia Ana , Stangaciu Cristina Sorina , Micea Mihai Victor , Curiac Daniel-Ioan
Published: September 2020

In mixed criticality systems (MCSs), the time-triggered scheduling approach focuses on a special case of safety-critical embedded applications which run in a time-triggered environment. Sometimes, for these types of MCSs, perfectly periodical (i.e., jitterless) scheduling for certain critical tasks is needed. In this paper, we propose FENP_MC (Fixed Execution Non-Preemptive Mixed Criticality), a real-time, table-driven, non-preemptive scheduling method specifically adapted to mixed criticality systems which guarantees jitterless execution in a mixed criticality time-triggered environment. We also provide a multiprocessor version, namely, P_FENP_MC (Partitioned Fixed Execution Non-Preemptive Mixed Criticality), using a partitioning heuristic. Feasibility tests are proposed for both uniprocessor and homogenous multiprocessor systems. An analysis of the algorithm performance is presented in terms of success ratio and scheduling jitter by comparing it against a time-triggered and an event-driven method in a non-preemptive context.
Formaldehyde Emission in Micron-Sized Wollastonite-Treated Plywood Bonded with Soy Flour and Urea-Formaldehyde Resin
Authors: Taghiyari Hamid R. , Hosseini Seyed Behzad , Ghahri Saman , Ghofrani Mohammad , Papadopoulos Antonios N.
Published: September 2020

Soy flour was partly substituted for urea-formaldehyde (UF) resin with different content to investigate its effect on formaldehyde emission in three-layer plywood panels. In each square meter of panels, 300 g of resin was used (wet weight basis of resin). Micron-sized wollastonite was added to the resin mixture at 5% and 10% consumption levels (wet weight basis of resin) to determine its potential effects as a reinforcing filler to mitigate the negative effects of addition of soy flour. Results showed a decreasing trend in formaldehyde emission as soy flour content increased to 20%. The highest shear-strength values were observed in panels with 10% and 15% soy flour content. The addition of wollastonite did not have a significant effect on formaldehyde emission, but it decreased the shear strength in soy-treated panels, although the values were still higher than those of control panels. Wollastonite significantly mitigated the negative effects of soy flour on the water absorption and thickness swelling of panels. It was concluded that 10% of soy flour and 5% of wollastonite provided the lowest formaldehyde emission and the most optimum physical and mechanical properties.
Development of a Mobile Personal Health Record Application Designed for Emergency Care in Korea; Integrated Information from Multicenter Electronic Medical Records
Authors: Choi Yuri , Kim June-sung , Kwon In Ho , Kim Taerim , Kim Su Min , Cha Wonchul , Jeong Jinwoo , Lee Jae-Ho
Published: September 2020

Collecting patient’s medical data is essential for emergency care. Although hospital-tethered personal health records (PHRs) can provide accurate data, they are not available as electronic information when the hospital does not develop and supply PHRs. The objective of this research was to evaluate whether a mobile app can assemble health data from different hospitals and enable interoperability. Moreover, we identified numerous barriers to overcome for putting health data into one place. The new mobile PHR (mPHR) application was developed and evaluated according to the four phases of the system development life cycle: defining input data and functions, developing a prototype, developing a mobile application, and implementation testing. We successfully introduced the FirstER (First for Emergency Room) platform on 23 September 2019. Additionally, validation in three tertiary hospitals has been carried out since the launch date. From 14 October to 29 November 2019, 1051 cases registered with the FirstER, and the total download count was 15,951 records. We developed and successfully implemented the mPHR service, which can be used as a health information exchange tool in emergency care, by integrating medical records from three different tertiary hospitals. By recognizing the significance and limitations of this service, it is necessary to study the development and implementation of mPHR services that are more suitable for emergency care.
Experimental and Kinetic Investigation on NO Reduction by Rice Husk Char and Catalytically with CO
Authors: Li Nan , Wang Yali , Cui Suping , Jin Xiaodong
Published: September 2020

Biomass char is accepted as an environmentally friendly energy resource, and is promising for NO removal in industrial furnaces. NO reduction with biomass char (rice husk) was investigated in a fixed-bed quartz reactor. The influence of CO concentration, reaction temperature, initial NO concentration, and char loading on the NO reduction were evaluated. The results showed that the overall NO reduction reaction was dominated by the direct reaction of NO with char without CO. Increasing CO concentration resulted in an enhanced catalytic reaction between NO and CO over the char surface and a decreased carbon consumption of char. With decreasing temperature, the influence of CO concentration on NO reduction was strengthened. Over the test temperature range, char provided a surface to catalyze the NO–CO reaction at excess CO/NO ratio. Increasing the initial NO concentration led to an increasingly significant influence on NO reduction with the enhanced CO/NO ratio. With increased char loading, the enhancement of NO reduction became unobservable for excess CO/NO ratio. Reaction orders of NO and activation energy for NO reduction by char were 0.71 and 60.21 kJ·mol−1, respectively, against 0.82 and 34.60 kJ·mol−1, respectively, for NO reduction by CO, catalyzed by char.
High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro
Authors: Torrente Laura , Maan Gunjit , Oumkaltoum Rezig Asma , Quinn Jean , Jackson Angus , Grilli Andrea , Casares Laura , Zhang Ying , Kulesskiy Evgeny , Saarela Jani , Bicciato Silvio , Edwards Joanne , Dinkova-Kostova Albena T. , de la Vega Laureano
Published: September 2020

Aberrant hyperactivation of nuclear factor erythroid 2 (NF-E2) p45-related factor 2 (NRF2) is a common event in many tumour types and associates with resistance to therapy and poor patient prognosis; however, its relevance in colorectal tumours is not well-established. Measuring the expression of surrogate genes for NRF2 activity in silico, in combination with validation in patients’ samples, we show that the NRF2 pathway is upregulated in colorectal tumours and that high levels of nuclear NRF2 correlate with a poor patient prognosis. These results highlight the need to overcome the protection provided by NRF2 and present an opportunity to selectively kill cancer cells with hyperactive NRF2. Exploiting the CRISPR/Cas9 technology, we generated colorectal cancer cell lines with hyperactive NRF2 and used them to perform a drug screen. We identified AT9283, an Aurora kinase inhibitor, for its selectivity towards killing cancer cells with hyperactive NRF2 as a consequence to either genetic or pharmacological activation. Our results show that hyperactivation of NRF2 in colorectal cancer cells might present a vulnerability that could potentially be therapeutically exploited by using the Aurora kinase inhibitor AT9283.
Construction Disputes in the UAE: Causes and Resolution Methods
Authors: El-Sayegh Sameh , Ahmad Irtishad , Aljanabi Malak , Herzallah Rawan , Metry Samuel , El-Ashwal Omar
Published: September 2020

Claims and disputes occur frequently in the construction industry between different contracting parties, mainly the owner, the designer and the contractor. Consequently, valuable time and a significant amount of money are lost. The United Arab Emirates (UAE) construction industry, one of the most vibrant sectors globally, is experiencing a high level of construction disputes and claims. This paper aims to identify and assess the major causes of disputes in the UAE and weigh the effectiveness of the methods used for their avoidance and resolution. The sources of disputes, and their avoidance/resolution methods, were identified through a comprehensive literature review. A survey was then developed and sent to 150 construction professionals. Fifty-four responses were received and analyzed. The results show that the top five sources of disputes in the UAE are variations initiated by the owner, obtaining permit/approval from the municipality and other governmental authorities, material change and approval during the construction phase, the slowness of the owner in decision-making, and the short time available during the design phase. As for the avoidance and the resolution method, the most effective method was found to be negotiation.
Catalytic Pyrolysis of a Residual Plastic Waste Using Zeolites Produced by Coal Fly Ash
Authors: Cocchi Marco , Angelis Doina De , Mazzeo Leone , Nardozi Piergianni , Piemonte Vincenzo , Tuffi Riccardo , Vecchio Ciprioti Stefano
Published: September 2020

The plastic film residue (PFR) of a plastic waste recycling process was selected as pyrolysis feed. Both thermal and catalytic pyrolysis experiments were performed and coal fly ash (CFA) and X zeolites synthesized from CFA (X/CFA) were used as pyrolysis catalysts. The main goal is to study the effect of low-cost catalysts on yields and quality of pyrolysis oils. NaX/CFA, obtained using the fusion/hydrothermal method, underwent ion exchange followed by calcination in order to produce HX/CFA. Firstly, thermogravimetry and differential scanning calorimetry (TG and DSC, respectively) analyses evaluated the effect of catalysts on the PFR degradation temperature and the process energy demand. Subsequently, pyrolysis was carried out in a bench scale reactor adopting the liquid-phase contact mode. HX/CFA and NaX/CFA reduced the degradation temperature of PFR from 753 to 680 and 744 K, respectively, while the degradation energy from 2.27 to 1.47 and 2.07 MJkg−1, respectively. Pyrolysis runs showed that the highest oil yield (44 wt %) was obtained by HX/CFA, while the main products obtained by thermal pyrolysis were wax and tar. Furthermore, up to 70% of HX/CFA oil was composed by gasoline range hydrocarbons. Finally, the produced gases showed a combustion energy up to 8 times higher than the pyrolysis energy needs.
Effective Electrodynamics Theory for the Hyperbolic Metamaterial Consisting of Metal–Dielectric Layers
Authors: Luan Pi-Gang
Published: September 2020

In this work, we study the dynamical behaviors of the electromagnetic fields and material responses in the hyperbolic metamaterial consisting of periodically arranged metallic and dielectric layers. The thickness of each unit cell is assumed to be much smaller than the wavelength of the electromagnetic waves, so the effective medium concept can be applied. When electromagnetic (EM) fields are present, the responses of the medium in the directions parallel to and perpendicular to the layers are similar to those of Drude and Lorentz media, respectively. We derive the time-dependent energy density of the EM fields and the power loss in the effective medium based on Poynting theorem and the dynamical equations of the polarization field. The time-averaged energy density for harmonic fields was obtained by averaging the energy density in one period, and it reduces to the standard result for the lossless dispersive medium when we turn off the loss. A numerical example is given to reveal the general characteristics of the direction-dependent energy storage capacity of the medium. We also show that the Lagrangian density of the system can be constructed. The Euler–Lagrange equations yield the correct dynamical equations of the electromagnetic fields and the polarization field in the medium. The canonical momentum conjugates to every dynamical field can be derived from the Lagrangian density via differentiation or variation with respect to that field. We apply Legendre transformation to this system and find that the resultant Hamiltonian density is identical to the energy density up to an irrelevant divergence term. This coincidence implies the correctness of the energy density formula we obtained before. We also give a brief discussion about the Hamiltonian dynamics description of the system. The Lagrangian description and Hamiltonian formulation presented in this paper can be further developed for studying the elementary excitations or quasiparticles in other hyperbolic metamaterials.
Analyzing Malaria Disease Using Effective Deep Learning Approach
Authors: Sriporn Krit , Tsai Cheng-Fa , Tsai Chia-En , Wang Paohsi
Published: September 2020

Medical tools used to bolster decision-making by medical specialists who offer malaria treatment include image processing equipment and a computer-aided diagnostic system. Malaria images can be employed to identify and detect malaria using these methods, in order to monitor the symptoms of malaria patients, although there may be atypical cases that need more time for an assessment. This research used 7000 images of Xception, Inception-V3, ResNet-50, NasNetMobile, VGG-16 and AlexNet models for verification and analysis. These are prevalent models that classify the image precision and use a rotational method to improve the performance of validation and the training dataset with convolutional neural network models. Xception, using the state of the art activation function (Mish) and optimizer (Nadam), improved the effectiveness, as found by the outcomes of the convolutional neural model evaluation of these models for classifying the malaria disease from thin blood smear images. In terms of the performance, recall, accuracy, precision, and F1 measure, a combined score of 99.28% was achieved. Consequently, 10% of all non-dataset training and testing images were evaluated utilizing this pattern. Notable aspects for the improvement of a computer-aided diagnostic to produce an optimum malaria detection approach have been found, supported by a 98.86% accuracy level.
Clinical Validation of a Urine Test (Uromonitor-V2®) for the Surveillance of Non-Muscle-Invasive Bladder Cancer Patients
Authors: Sieverink Caroline A. , Batista Rui P. M. , Prazeres Hugo J. M. , Vinagre João , Sampaio Cristina , Leão Ricardo R. , Máximo Valdemar , Witjes J. Alfred , Soares Paula
Published: September 2020

The costly and burdensome nature of the current follow-up methods in non-muscle-invasive bladder cancer (NMIBC) drives the development of new methods that may alternate with regular cystoscopy and urine cytology. The Uromonitor-V2® is a new urine-based assay in the detection of hotspot mutations in three genes (TERT, FGFR3, and KRAS) for evaluation of disease recurrence. The aim of this study was to investigate the Uromonitor-V2®’s performance in detecting NMIBC recurrence and compare it with urine cytology. From February 2018 to September 2019 patients were enrolled. All subjects underwent a standard-of-care (SOC) cystoscopy, either as part of their follow-up for NMIBC or for a nonmalignant urological pathology. Urine cytology was performed in NMIBC patients. Out of the 105 patients enrolled, 97 were eligible for the study. Twenty patients presented nonmalignant lesions, 29 had a history of NMIBC with disease recurrence, and 49 had a history of NMIBC without recurrence. In NMIBC, the Uromonitor-V2® displayed a sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 93.1%, 85.4%, 79.4%, and 95.3%, respectively. Urine cytology was available for 52 patients, and the sensitivity, specificity, PPV, and NPV were 26.3%, 90.9%, 62.5%, and 68.2%, respectively. With its high NPV of 95.3%, the Uromonitor-V2® revealed promising properties for the follow-up of patients with NMIBC.
Development of a Clinical MALDI-ToF Mass Spectrometry Assay for SARS-CoV-2: Rational Design and Multi-Disciplinary Team Work
Authors: Iles Ray K. , Zmuidinaite Raminta , Iles Jason K. , Carnell George , Sampson Alex , Heeney Jonathan L.
Published: September 2020

The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus has stretched national testing capacities to breaking points in almost all countries of the world. The need to rapidly screen vast numbers of a country’s population in order to control the spread of the infection is paramount. However, the logistical requirement for reagent supply (and associated cost) of RT-PCR based testing (the current front-line test) have been hugely problematic. Mass spectrometry-based methods using swab and gargle samples have been reported with promise, but have not approached the task from a systematic analysis of the entire diagnostic process. Here, the pipeline from sample processing, the biological characteristics of the pathogen in human biofluid, the downstream bio- and physical-chemistry and the all-important data processing with clinical interpretation and reporting, are carefully compiled into a single high-throughput and reproducible rapid process. Utilizing MALDI-ToF mass spectrometric detection to viral envelope glycoproteins in a systems biology-multidisciplinary team approach, we have achieved a multifaceted clinical MALDI ToF MS screening test, primarily (but not limited to) SARS-CoV-2, with direct application to other future epidemics/pandemics that may arise. The clinical information generated not only includes SARS-CoV-2 coronavirus detection–(Spike protein fragments S1, S2b, S2a peaks), but other respiratory viral infections detected as well as an assessment of generalised oral upper respiratory immune response (elevated total Ig light chain peak) and a measure of the viral immune response (elevated intensity of IgA heavy chain peak). The advantages of the method include; (1) ease of sampling, (2) speed of analysis, and much reduced cost of testing. These features reveal the diagnostic utility of MALDI-ToF mass spectrometry as a powerful and economically attractive global solution
Erratum: Korkovelos, A., et al. The Role of Open Access Data in Geospatial Electrification Planning and the Achievement of SDG7. An OnSSET-Based Case Study for Malawi. Energies 2019, 12(7), 1395
Authors: Korkovelos Alexandros , Khavari Babak , Sahlberg Andreas , Howells Mark , Arderne Christopher , Mentis Dimitrios
Published: September 2020

The authors wish to make a change in author names (adding new author—Dimitrios Mentis) to this paper [...]
Multiscale Modeling for Reversible Solid Oxide Cell Operation
Authors: Bianchi Fiammetta Rita , Baldinelli Arianna , Barelli Linda , Cinti Giovanni , Audasso Emilio , Bosio Barbara
Published: September 2020

Solid Oxide Cells (SOCs) can work efficiently in reversible operation, allowing the energy storage as hydrogen in power to gas application and providing requested electricity in gas to power application. They can easily switch from fuel cell to electrolyzer mode in order to guarantee the production of electricity, heat or directly hydrogen as fuel depending on energy demand and utilization. The proposed modeling is able to calculate effectively SOC performance in both operating modes, basing on the same electrochemical equations and system parameters, just setting the current density direction. The identified kinetic core is implemented in different simulation tools as a function of the scale under study. When the analysis mainly focuses on the kinetics affecting the global performance of small-sized single cells, a 0D code written in Fortran and then executed in Aspen Plus is used. When larger-scale single or stacked cells are considered and local maps of the main physicochemical properties on the cell plane are of interest, a detailed in-home 2D Fortran code is carried out. The presented modeling is validated on experimental data collected on laboratory SOCs of different scales and electrode materials, showing a good agreement between calculated and measured values and so confirming its applicability for multiscale approach studies.
Small Multispectral UAV Sensor and Its Image Fusion Capability in Cultural Heritage Applications
Authors: Kaimaris Dimitris , Kandylas Aristoteles
Published: September 2020

For many decades the multispectral images of the earth’s surface and its objects were taken from multispectral sensors placed on satellites. In recent years, the technological evolution produced similar sensors (much smaller in size and weight) which can be placed on Unmanned Aerial Vehicles (UAVs), thereby allowing the collection of higher spatial resolution multispectral images. In this paper, Parrot’s small Multispectral (MS) camera Sequoia+ is used, and its images are evaluated at two archaeological sites, on the Byzantine wall (ground application) of Thessaloniki city (Greece) and on a mosaic floor (aerial application) at the archaeological site of Dion (Greece). The camera receives RGB and MS images simultaneously, a fact which does not allow image fusion to be performed, as in the standard utilization procedure of Panchromatic (PAN) and MS image of satellite passive systems. In this direction, that is, utilizing the image fusion processes of satellite PAN and MS images, this paper demonstrates that with proper digital processing the images (RGB and MS) of small MS cameras can lead to a fused image with a high spatial resolution, which retains a large percentage of the spectral information of the original MS image. The high percentage of spectral fidelity of the fused images makes it possible to perform high-precision digital measurements in archaeological sites such as the accurate digital separation of the objects, area measurements and retrieval of information not so visible with common RGB sensors via the MS and RGB data of small MS sensors.
Chronic Facial Pain: Trigeminal Neuralgia, Persistent Idiopathic Facial Pain, and Myofascial Pain Syndrome—An Evidence-Based Narrative Review and Etiological Hypothesis
Authors: Gerwin Robert
Published: September 2020

Trigeminal neuralgia (TN), the most common form of severe facial pain, may be confused with an ill-defined persistent idiopathic facial pain (PIFP). Facial pain is reviewed and a detailed discussion of TN and PIFP is presented. A possible cause for PIFP is proposed. (1) Methods: Databases were searched for articles related to facial pain, TN, and PIFP. Relevant articles were selected, and all systematic reviews and meta-analyses were included. (2) Discussion: The lifetime prevalence for TN is approximately 0.3% and for PIFP approximately 0.03%. TN is 15–20 times more common in persons with multiple sclerosis. Most cases of TN are caused by neurovascular compression, but a significant number are secondary to inflammation, tumor or trauma. The cause of PIFP remains unknown. Well-established TN treatment protocols include pharmacotherapy, neurotoxin denervation, peripheral nerve ablation, focused radiation, and microvascular decompression, with high rates of relief and varying degrees of adverse outcomes. No such protocols exist for PIFP. (3) Conclusion: PIFP may be confused with TN, but treatment possibilities differ greatly. Head and neck muscle myofascial pain syndrome is suggested as a possible cause of PIFP, a consideration that could open new approaches to treatment.
Effect of Flowable Thrombin-Containing Collagen-Based Hemostatic Matrix for Preventing Pancreatic Fistula after Pancreatectomy: A Randomized Clinical Trial
Authors: Park Yejong , Ko Jae Hyung , Kang Dae Ryong , Lee Jun Hyeok , Hwang Dae Wook , Lee Jae Hoon , Lee Woohyung , Kwon Jaewoo , Park Si-Nae , Song Ki-Byung , Kim Song Cheol
Published: September 2020

Background: The aim of this study was to evaluate the safety and efficacy of a flowable hemostatic matrix, and their effects for postoperative pancreatic fistula (POPF) after pancreatectomy. Methods: This was a randomized, clinical, single-center, single-blind (participant), non-inferiority, phase IV, and parallel-group trial. The primary endpoint was the incidence of POPF. The secondary endpoints were risk factors for POPF, drain removal days, incidence of complication, 90-day mortality, and length of hospital stay. Results: This study evaluated a total of 53 patients, of whom 26 patients were in the intervention group (flowable hemostatic matrix) and 27 patients were in the control group (thrombin-coated collagen patch). POPF was more common in the control group than in the intervention group (59.3% vs. 30.8%, p = 0.037). Among participants who underwent distal pancreatectomy, POPF (33.3% vs. 92.3%, p = 0.004), and clinically relevant POPF (8.3% vs. 46.2%, p = 0.027) was more common in the control group. A multivariate logistic regression model identified flowable hemostatic matrix use as an independent negative risk factor for POPF, especially in cases of distal pancreatectomy (DP) (odds ratio 17.379, 95% confidential interval 1.453–207.870, p = 0.024). Conclusion: Flowable hemostatic matrix application is a simple, feasible, and effective method of preventing POPF after pancreatectomy, especially for patients with DP. Non-inferiority was demonstrated in the efficacy of preventing POPF in the intervention group compared to the control group.
Physicochemical and Antibacterial Properties of Novel, Premixed Calcium Silicate-Based Sealer Compared to Powder–Liquid Bioceramic Sealer
Authors: Kharouf Naji , Arntz Youri , Eid Ammar , Zghal Jihed , Sauro Salvatore , Haikel Youssef , Mancino Davide
Published: September 2020

The aim of this study was to compare the physicochemical properties, filling ability, and antibacterial activity of a premixed calcium silicate-based sealer to those of a powder–liquid bioceramic sealer. Ceraseal (CS) and BioRoot (BR) materials were analyzed using scanning electron microscopy and energy-dispersive X-ray spectroscopy at 7 and 14 d of immersion in distilled water. The filling ability of the two sealers as well as the water contact angle, solubility, flow, roughness, crystalline microstructure, pH, and compressive strength were also evaluated. The antibacterial activity was assessed through an agar diffusion as well as through direct tests. All the results were statistically analyzed using one-way or two-way analysis of variance tests. Statistically significant lower void percentages were observed for CS at 2 and 8 mm from the working length (WL) compared to those for the BR group, whilst no significant difference was observed at 5 mm from the WL. BR sealer showed higher alkaline pH, rougher surface, lower water contact angle values, lower flowability, and higher solubility compared to CS. BR showed globular and needle-like crystalline microstructure, whilst CS had globular and flower-like crystalline microstructure up to 72 h. No statistical difference was found for the compressive strength between the two sealers. BR and CS showed no antibacterial effect against Enterococcus faecalis after 3 h, whilst both sealers showed antibacterial capacity after 24 and 72 h. BR demonstrated higher antibacterial activity after 24 h. In conclusion, the use of bioceramic sealers may play an important role in controlling bacterial growth. Moreover, CS may have superior filling ability and lower solubility than the BioRoot sealer due to its specific chemical composition and mixing method.
High-Intensity Interval Training Is Effective at Increasing Exercise Endurance Capacity and Is Well Tolerated by Adults with Cystic Fibrosis
Authors: Sawyer Abbey , Cavalheri Vinicius , Jenkins Sue , Wood Jamie , Cecins Nola , Bear Natasha , Singh Bhajan , Gucciardi Daniel , Hill Kylie
Published: September 2020

Background: To optimize outcomes in people with cystic fibrosis (CF), guidelines recommend 30 to 60 min of moderate-intensity aerobic exercise on most days. Accumulating this volume of exercise contributes importantly to the substantial treatment burden associated with CF. Therefore, the main aim of this study was to investigate the effects of low-volume high-intensity interval training (HIIT) on exercise capacity in people with CF. Methods: This randomized controlled trial included people with CF aged ≥15 years, who were allocated to either eight weeks of thrice-weekly 10-min sessions of HIIT (experimental group) or eight weeks of weekly contact (control group). Before and after the intervention period, participants completed measurements of time to symptom limitation (Tlim) during a constant work rate cycle ergometry test (primary outcome), and maximal work rate (Wmax) during a ramp-based cycle ergometry test and health-related quality of life (HRQoL). Results: Fourteen participants (median (IQR) age 31 (28, 35) years, forced expiratory volume in 1 second (FEV1) 61 (45, 80) % predicted) were included (seven in each group). Compared to the control group, participants in the experimental group demonstrated a greater magnitude of change in Tlim, Wmax (p = 0.017 for both) and in the physical function domain of HRQoL (p = 0.03). No other between-group differences were demonstrated. Mild post-exercise muscle soreness was reported on a single occasion by four participants. Overall, participants attended 93% of all HIIT sessions. Discussion: Eight weeks of low-volume (i.e., 30-min/week) HIIT produced gains in exercise capacity and self-reported physical function and was well tolerated by people with CF.
Paroxysmal Symptoms in Multiple Sclerosis—A Review of the Literature
Authors: Freiha Joumana , Riachi Naji , Chalah Moussa A. , Zoghaib Romy , Ayache Samar S. , Ahdab Rechdi
Published: September 2020

Paroxysmal symptoms are well-recognized manifestations of multiple sclerosis (MS). These are characterized by multiple, brief, sudden onset, and stereotyped episodes. They manifest as motor, sensory, visual, brainstem, and autonomic symptoms. When occurring in the setting of an established MS, the diagnosis is relatively straightforward. Conversely, the diagnosis is significantly more challenging when they occur as the initial manifestation of MS. The aim of this review is to summarize the various forms of paroxysmal symptoms reported in MS, with emphasis on the clinical features, radiological findings and treatment options.
Pharmaconutrition in the Clinical Management of COVID-19: A Lack of Evidence-Based Research But Clues to Personalized Prescription
Authors: Santos Heitor O. , Tinsley Grant M. , da Silva Guilherme A. R. , Bueno Allain A.
Published: September 2020

A scientific interest has emerged to identify pharmaceutical and nutritional strategies in the clinical management of coronavirus disease 2019 (COVID-19). The purpose of this narrative review is to critically assess and discuss pharmaconutrition strategies that, secondary to accepted treatment methods, could be candidates in the current context of COVID-19. Oral medicinal doses of vitamin C (1–3 g/d) and zinc (80 mg/d elemental zinc) could be promising at the first signs and symptoms of COVID-19 as well as for general colds. In critical care situations requiring parenteral nutrition, vitamin C (3–10 g/d) and glutamine (0.3–0.5 g/kg/d) administration could be considered, whereas vitamin D3 administration (100,000 IU administered intramuscularly as a one-time dose) could possess benefits for patients with severe deficiency. Considering the presence of n-3 polyunsaturated fatty acids and arginine in immune-enhancing diets, their co-administration may also occur in clinical conditions where these formulations are recommended. However, despite the use of the aforementioned strategies in prior contexts, there is currently no evidence of the utility of any nutritional strategies in the management of SARS-CoV-2 infection and COVID-19. Nevertheless, ongoing and future clinical research is imperative to determine if any pharmaconutrition strategies can halt the progression of COVID-19.
Experimental Research on Water Droplet Erosion Resistance Characteristics of Turbine Blade Substrate and Strengthened Layers Materials
Authors: Di Juan , Wang Shunsen , Yan Xiaojiang , Jiang Xihang , Lian Jinyi , Zhang Zheyuan , Xie Yonghui
Published: September 2020

In this paper, the water droplet erosion (WDE) performance of typical martensitic precipitation substrate 0Cr17Ni4Cu4Nb in steam turbine final stage, laser solid solution strengthened sample, laser cladding sample and brazed stellite alloy samples have been studied based on a high-speed rotating waterjet test system. The WDE resistance of several materials from strong to weak is in sequence: Brazed stellite alloy > laser cladding sample > laser solid solution sample > martensitic substrate. Furthermore, the WDE resistance mechanism and the failure mode of brazed stellite alloy have been revealed. It is found that the hard carbide in the stellite alloy is the starting point of crack formation and propagation. Under the continuous droplet impact, cracks grow and connect into networks, resulting in the removal of carbide precipitates and WDE damage. It is proved that the properties of the Co-based material itself is the reason for its excellent WDE resistance. And the carbides have almost no positive contribution to its anti-erodibility. These new findings are of great significance to process methods and parameter selection of steam turbine blade materials and surface strengthened layers.
Efficacy of Mushroom Metabolites (Pleurotus ostreatus) as A Natural Product for the Suppression of Broomrape Growth (Orobanche crenata Forsk) in Faba Bean Plants
Authors: Elsakhawy Tamer , ALKahtani Muneera D. F. , Sharshar Ali A. H. , Attia Kotb A. , Hafez Yaser M. , Abdelaal Khaled A. A.
Published: September 2020

Broomrape parasitism on faba bean (Vicia faba L.) is the most destructive factor for this crop in Egypt. Pot experiments were conducted during the two successive seasons 2017/2018 and 2018/2019 to study the mitigation of broomrape stress on faba bean using a ten-fold dilution of 10% (w/v) spent mushroom substrate extract (SMSE) of Pleurotus ostreatus and the same dilution of culture filtrate of mushroom (MCF) grown in potato dextrose broth (PDB) at a rate of 48 l hectare−1 compared with the commercial herbicide Roundup (Glyphosate 48% emulsifiable concentrate) at a rate of 144 cm3 ha−1 on the two varieties (Misr3 and Sakha3) cultivated in broomrape-infested soil. The treatments include the use of mushroom products as foliar spray and/or soil amendment in addition to Roundup spraying as a recommended treatment. Using Gas Chromatography-Mass Spectrometry (GC-MS) spectroscopy, our results indicate that the major components of the two mushroom products were bioactive compounds such as polyphenol and high molecular weight aliphatic and aromatic hydrocarbons that may interfere with parasite and host metabolism. These results indicated that SMSE of P. ostreatus and MCF of the same mushroom grown in potato dextrose broth (PDB) gave the best control of broomrape, and increased plant height, root length, leaf area, chlorophyll concentration, relative water content and seed yield (g plant−1), as well as anatomical characters of leaves in the two faba bean varieties (Misr3 and Sakha3), such as upper and lower epidermis, palisade tissue, spongy tissue and vascular bundles. Additionally, electrolyte leakage was decreased in the treated plants compared to control plants and the plants treated with Roundup (glyphosate) because of the important role of SMSE and MCF in the improvement of faba bean water status.
Assembly of MXene/PP Separator and Its Enhancement for Ni-Rich LiNi0.8Co0.1Mn0.1O2 Electrochemical Performance
Authors: Rao Qiu-Shi , Liao Song-Yi , Huang Xing-Wen , Li Yue-Zhu , Liu Yi-Dong , Min Yong-Gang
Published: September 2020

In this work, a few-layer MXene is prepared and sprinkled on a commercial polypropylene (PP) separator by a facile spraying method to enhance the electrochemistry of the Ni-rich LiNi0.8Co0.1Mn0.1O2 (NCM811) cathode. Scanning electron microscope (SEM) and X-ray diffraction (XRD) are used to characterize the morphology and structure of MXene. Fourier transform infrared spectroscopy (FT-IR) and a contact angle tester are used to measure the bond structure and surface wettability PP and MXene/PP separator. The effect of the MXene/PP separator on the electrochemical performance of ternary NCM811 material is tested by an electrochemical workstation. The results show that the two-dimensional MXene material could improve the wettability of the separator to the electrolyte and greatly enhance the electrochemical properties of the NCM811 cathode. During 0.5 C current density cycling, the Li/NCM811 cell with MXene/PP separator remains at 166.2 mAh/g after the 100 cycles with ~90.7% retention. The Rct of MXene/PP cell is measured to be ~28.0 Ω. Combining all analyses results related to MXene/PP separator, the strategy by spraying the MXene on commercial PP is considered as a simple, convenient, and effective way to improve the electrochemical performance of the Ni-rich NCM811 cathode and it is expected to achieve large-scale in high-performance lithium-ion batteries in the near future.
Online Discourse in the Context of COVID-19, the First Health Crisis in China after the Advent of Mobile Social Media: A Content Analysis of China’s Weibo and Baidu
Authors: Carvajal-Miranda Christian , Mañas-Viniegra Luis , Liang Li
Published: September 2020

The COVID-19 epidemic was the first universal health crisis since China entered the era of mobile social media. When Severe Acute Respiratory Syndrome (SARS) broke out in 2003, it was not until almost six years later that Weibo was born, marking China’s entry into the era of mobile social media (Weixin 2020). In this context, this research analysed the role of the social media platform Weibo and the Internet search browser Baidu, in a government controlled online media environment, during the COVID-19 pandemic. In order to undertake this study, we applied the use of content and sentiment analysis to the discourse identified through the topics published during the investigation period, which encompassed 15 December 2019 until 15 March 2020. From the findings of this study, we concluded that, during the pre- and post-COVID-19 period, there was an important presence of social and lifestyle topic categories dominating the online discourse, which dramatically changed in correlation to the increasing spread of the disease. Additionally, there was a marked absence of topics in relation to economic and political information, and there was a notable absence of an official Government “voice” generating topics.
Marketing in the Public Sector—Benefits and Barriers: A Bibliometric Study from 1931 to 2020
Authors: Matos Nelson de , Correia Marisol B. , Saura José Ramón , Reyes-Menendez Ana , Baptista Nuno
Published: September 2020

The global economy has brought economic and social changes that have led organizations to extend their vision beyond consumer and business markets. Particularly, in the marketing of public sector (MPS), the extant theoretical foundations require more comprehensive investigations not only into the main topics researchers have looked into the past, but also into the new challenges they will face in the future. Thus, the purpose of this study is to provide a thorough a bibliometric overview of the theoretical framework and to identify benefits and barriers of marketing in the public sector. We provide an overview of the theoretical framework and identify the benefits and barriers of marketing in the public sector through a bibliometric study. To achieve this objective, a systematic literature review was conducted of 3926 articles from 1931 to 2020. The results allowed the identification of four main theoretical clusters: educational, public health, social economics and urban politics. It also offered benefits and barriers in the context of MPS. Conclusions and implications to the academia and managers are drawn. Future research opportunities are also provided.
Elaboration of Social Media Performance Measures: From the Perspective of Social Media Discontinuance Behavior
Authors: Kang Inwon , Zhang Yiya , Yoo Sungjoon
Published: September 2020

Social media platforms insist on the so-called “number of visits, clicking, and subscription” as a measurement of social media performance. However, this method of measurement does not take into account dormant user accounts and unintentional clicks or visits. To fully understand social media performance, this study aims to examine the process of users’ discontinuance behavior from the view of technostress creators and socialstress creators through social media fatigue. Also, this study investigates the influence of involvement between social media fatigue and discontinuance behaviors. To understand the impact of technostress and social stress creators on users’ discontinuance behavior, this study conducted an off- and online survey in Korea. Using Confirmatory factory analysis (CFA), this study has a strong academic contribution because it identifies the existing methods measuring social media performance through numbers of accounts or joining in as inaccurate.