bluuebunny/crossref_metadata_2025 huggingface dataset:
Management of the adverse effects of targeted therapy for cancer
Authors: Ryu Hyewon
Published: March 2023

Background: Advances in genomics and molecular biology over the past 20 years have resulted in numerous approved molecular targeted cancer therapies. The two main approaches for targeted cancer therapy are monoclonal antibodies and small molecules. Targeted therapy is expected to exert few side effects, but a new class of toxicities has been reported. Thus, the classical chemotherapy-induced toxicities of alopecia, myelosuppression, mucositis, nausea, and vomiting have been replaced in patients receiving targeted therapies by dermatologic, cardiovascular, gastrointestinal, endocrine, ocular, and pulmonary toxicities, and infusion reactions.Current Concepts: Targeted therapy toxicities vary, but common side effects include skin rash, diarrhea, and stomatitis. Most of these side effects are mild and can be prevented and treated. Rare and dangerous side effects, including pneumonitis, cardiotoxicities, and infusion reactions, can also be induced by targeted therapies. In most cases, toxicities are low grade (grade ≤2) and can be treated effectively, but in some cases, they can be fatal without appropriate intervention. Symptoms can be nonspecific, rendering identification of early symptoms challenging. Physicians should thus be aware of these side effects and manage toxicities appropriately.Discussion and Conclusion: The side effects of targeted therapy exert a critical impact on survival and quality of life. Most patients receiving targeted therapy need help to prevent and relieve toxicities. Management of the toxicities of targeted therapy involves patient monitoring, adjusting therapeutic dose or frequency, and providing supportive care. Serious side effects require early detection and prompt intervention, including discontinuation of targeted therapy and the use of corticosteroids.
Diagnosis and treatment of sodium hypochlorite poisoning with ingestion of household bleaching agents
Authors: Moon Jeong Mi , Chun Byeong Jo , Cho Yong Soo
Published: March 2023

Background: Sodium hypochlorite is commonly used as a household bleaching agent (for example, the Clorox brand). Sodium hypochlorite poisoning with ingestion of a bleaching agent is often observed in clinical practice.Current Concepts: Ingestion (intentional or accidental) is the most common route of exposure to household bleaching agents. Accidental ingestion of household bleaching agents is rarely clinically important. However, ingestion of a large amount of a dilute formulation or a high-concentration preparation of bleaching agents can result in severe and rarely fatal corrosive injury. Therefore, prompt supportive care is essential because a specific antidote is currently unavailable. Severe poisoning requires hospital admission. Emergency endoscopy and thoracic and abdominal computed tomography are warranted to aid with diagnosis and management of hypochlorite-induced corrosive injury in patients with severe poisoning, who develop clinical features suggestive of corrosive injury.Discussion and Conclusion: Intentional poisoning, which accounts for most cases of household bleaching agent poisonings in Korea, is likely to cause severe corrosive injuries. Therefore, it is necessary to gain deeper and accurate understanding of the clinical aspects and treatment of poisoning by household bleaching agents.
Obesity: etiology and the problems it causes
Authors: Çifci Aydın , Öklü Kübra
Published: March 2023

Obesity is one of the biggest health problems today and its prevalence is increasing. It develops with excessive fat accumulation in the body secondary to high energy intake in obesity. It is a chronic disease in which the interaction of genetic, endocrine, metabolic, behavioral, psychological and sociocultural factors plays a role. In addition to endocrine (type 2 diabetes mellitus and insulin resistance, metabolic syndrome, etc.), cardiovascular (hypertension, hyperlipidemia, etc.) and cerebrovascular diseases, diseases such as cholecystitis, sleep apnea, osteoarthritis, hyperuricemia and gout, endometrial, breast, gallbladder cancers in women are associated with diseases such as colon, rectum, prostate cancer in men. These diseases both reduce the quality of life and lead to financial losses in individuals and national economies. Today, preventive health policies aim to reduce morbidity, mortality and economic burden by treating obesity without causing chronic diseases.
Gravámenes de salida sobre personas físicas en el derecho tributario español, derecho convencional y en el derecho comunitario
Authors: Martínez-Carrasco Pignatelli José Miguel
Published: March 2023

El ordenamiento jurídico tributario español contiene medidas de blindaje del interés recaudatorio de la Hacienda Pública frente a los intentos de deslocalización indiscriminada por personas físicas. Y, en concreto, respecto de aquellos contribuyentes del impuesto sobre la renta de las personas físicas con una elevada capacidad económica contributiva, expresada en la tenencia de valores financieros reveladores de la misma.
En opinión del autor, la regulación y exigencia de gravámenes de salida constituye, se quiera o no, una restricción que distorsiona el libre movimiento de capitales y de empresas y el principio de libertad de establecimiento.
Los gravámenes de salida previstos en el ordenamiento tributario español restringen la libre competencia y la expansión de las empresas. La consecuencia inmediata de su existencia es ahuyentar a grandes contribuyentes corporativos y a inversores internacionales, disuadiéndoles o frenándoles en su deseo de establecer su residencia fiscal en España. Efecto a todas luces, contraproducente.
The middle stabilizing role of perennial grasses in modern challenges of ecological and climatic character
Authors:   Russian Timiryazev State Agrarian University, Belolyubcev Aleksandr , Kupriyanov Aleksey , Kuznetsov Ivan , Beresneva Elena , Astafeva Nadezhda , Brovkin Aleksei
Published: March 2023

It is shown that in the development and application of soil-protective measures on erosion-prone territories, it is extremely important to take into account soil and climatic features of natural ecosystems. The global warming observed in the last decades has a special sense and importance for the Russian Federation by virtue of its physical and geographical position and agricultural climate opportunities. New natural resource potential of light, heat and moisture formed on this basis, significant growth of climate extremes and dangerous hydrometeorological phenomena (droughts, overmoistening, hailstorms, frost etc.) of the Central Non-Chernozem area violate sustainability of agricultural sector. They reduce the production potential of agrolandscapes, bring noticeable destabilization in the processes of soil formation, ecological regimes of soils, processes of growth, development and productivity of field crops. To the same extent, and as long-term studies show, even to a much greater extent, this can be said for areas located on sloping lands. Climate changes as a result of warming bring to reorganization of arable horizon with deterioration of its agrophysical basis: increase of density by 3...5 % and hardness by 20...22 %, reduction of agronomically valuable macrostructure by 10...19 %, weakening of water capacity of soil units by 9...13 %, worsening of nutrition and water regime that in the end negatively affects productivity of agrolandscapes and their ecological stability. It is hardly possible to solve the problem of soil degradation as a result of erosion by applying individual elements of the complex of soil protective measures. Only a systematic approach will allow to obtain the proper ecological and economic effect on sloping lands, where soil-protective grain-grass crop rotation plays a leading role. Key words: CLIMATE CHANGE, SLOPING LAND, NORTHERN DEVELOPMENT, CROWN AGRICULTURE, SOIL EROSION
Yield and economic assessment of corn cultivation (RNIISK 1) using irrigation technologies and mineral fertilizers
Authors:   Russian Research Institute for Sorghum and Maize “Rossorgo”, Vasilyeva Elena , Zaitsev Sergey , Bashinskaya Oksana , Levkina Albina , Rozhkov Pavel , Sadovova Anastasia
Published: March 2023

Corn (Zea mays L.) is popular not only among agricultural producers, but also among consumers because of its benefits for a healthy lifestyle. The main task of corn producers is to obtain high yields of high-quality corn, including in regions with adverse weather conditions. In this regard, it is important to use scientifically sound irrigation systems (in relation to the specifics of each specific region and enterprise) in combination with the application of mineral fertilizers. The article presents the results of studies of the impact of various irrigation technologies, including the use of mineral fertilizers, on the yield of corn RNIISK 1. An economic assessment of the results of scientific research is given. Keywords: CORN, ELEMENT, TECHNOLOGY, SEED PRODUCTION, HYBRID, LINE, IRRIGATION, FERTILIZER, ECONOMIC EFFICIENCY
MONEY MARKET INSTRUMENTS ON THE DEVELOPMENT OF THE FINANCIAL SECTOR IN NIGERIA
Authors: Victor Chukwunweike EHIEDU  , Anastasia Chi-Chi ONUORAH  , Regina Nma, AKUBUE
Published: March 2023

This investigation inspected the impact of money market instruments (MMIs) on the development of the financial area in Nigeria for the period 2000 – 2018. The information for the examination were sourced from the Central Bank of Nigeria (CBN) Statistical Bulletin. The examination utilized econometric strategies like Unit Root Test, numerous relapse and Granger Causality Test to dissect information gathered from the investigation. the examination of information, a relapse model of the accompanying request was created to catch the causality connection between TBs, CPs, BAs and Banking Sector GDP. This investigation on the connection between depository charges (TBs) Commercial paper (CPs), Bank acceptances (BAs) and banking area GDP (the reliant variable) while TBs, CPs, and BAs utilized as intermediary for currency market are the autonomous factors. The investigation utilized ex-post facto research plan which manages previously existing information. The ordinary least square model assessment uncovered explicitly that (MMIs (depository charges, business papers, and government security) have positive connections and critical impacts on bank execution in Nigeria. Quite, depository charges, business papers and government bonds were the fundamental supporters of bank execution while investors’ acknowledgment has a negative relationship and essentially affected unfavorably on bank execution. The examination suggested that, arrangement creators and partners in the business ought to escalate endeavors towards further developing strategies and changes that support interest in money market instruments by banks for more prominent execution and maintainable development.
Keywords: Bank Performance, Bankers Acceptance, Commercial Papers and Treasury Bills.
RICE PRODUCTION, IMPORTS AND ECONOMIC GROWTH IN NIGERIA: AN APPLICATION OF AUTOREGRESSIVE DISTRIBUTED LAG
Authors: Babatunde Peter Ekundayo
Published: March 2023

Inconsistent and inefficient policies, climate issues and general poor funding have been adjudged to hinder increased domestic rice production in Nigeria. Rather than tackling these challenges, the nation has continued to opt for importation to supplement her domestic production, if not for recently, as a ‘stop-gap’ for food security. Geared towards strengthening the resilient efforts of the small holder farmers and driving increased rice production, this paper examined the trends in rice imports and production between 1980 and 2021; and also identified the determinants of rice imports in Nigeria. Secondary data were used for this study, while descriptive statistics and ARDL model were used to analyze the data. The results showed that the average quantities of rice production and rice imports were 3.51 and 0.24 million tons over the periods. The periods between 1998 and 2007 experienced a wide volatility of rice imports over rice production. Again, the results of ARDL model implied that exchange rate, GDP and quantity of rice production were statistically significant in influencing changes in the quantity of rice imports in the area. Therefore, since GDP and quantity of rice production had negative relationship with rice imports, it would be suggested that efforts geared at increasing rice production in Nigeria should be tailored at revamping agricultural extension services to enhance a genuine two-way communication between researchers and the farmers vis-à-vis increase food production.

Keywords: Rice Imports, Trends, Rice Production, ARDL Model, Nigeria.
Anisotropie et propriétés mécaniques
Authors: RÉGLÉ Hélène , BACROIX Brigitte
Published: March 2023

Ce chapitre traite de l’influence du développement de textures cristallographiques sur l’anisotropie. Un rappel est fait des composantes de texture dans les phases ferrite et austénite, présentes dans les nouveaux aciers. Les textures héritées lors de la transformation de phase sont décrites. L’impact des textures est modélisé sur l’anisotropie du module d’Young, du coefficient de Langford et de la surface de plasticité.
Compromis entre résistance mécanique et tenue en fatigue
Authors: FAVIER Véronique , GALTIER André , MUNIER Rémi , WEBER Bastien
Published: March 2023

Ce chapitre rappelle les principales caractéristiques de la tenue en fatigue, essentielle pour la plupart des pièces de structure en acier. Il aborde ensuite l’influence des nouvelles microstructures sur l’amorçage et la propagation des fissures, ainsi que les moyens d’améliorer la tenue en fatigue par des traitements thermiques et mécaniques adaptés à ces nouvelles nuances d’acier.
Forecasting estuarine salt intrusion in the Rhine-Meuse delta using an LSTM model
Authors: Wullems Bas Johan Marinus , Brauer Claudia Catharina , Baart Fedor , Weerts Albrecht Henricus
Published: March 2023

Abstract. Estuarine salt intrusion causes problems with freshwater availability in many deltas. Water managers require timely and accurate forecasts to be able to mitigate and adapt to salt intrusion. Data-driven models derived with machine learning are ideally suited for this, as they can mimic complex non-linear systems and are computationally efficient. We set up a Long Short Term Memory (LSTM) model to forecast salt intrusion in the Rhine-Meuse delta. It forecasts chloride concentrations up to 7 days ahead at Krimpen aan den IJssel, an important location for freshwater provision. The model forecasts baseline concentrations and peak timing well, but peak height is underestimated, a problem that becomes worse with increasing lead time. Between lead times of 1 and 7 days, forecast precision declines from 0.9 to 0.7 and forecast recall declines from 0.7 to 0.5 on average. Given these results, we aim to extend the model to other locations in the delta. We expect that a similar setup can work in other deltas, especially those with a similar or simpler channel network.
Molecular simulations reveal that heterogeneous ice nucleation occurs at higher temperatures in water under capillary tension
Authors: Rosky Elise , Cantrell Will , Li Tianshu , Nakamura Issei , Shaw Raymond A.
Published: March 2023

Abstract. Homogeneous ice nucleation rates occur at higher temperatures when water is under tension, otherwise referred to as negative pressure. If also true for heterogeneous ice nucleation rates, then this phenomenon can result in higher heterogeneous freezing temperatures in water capillary bridges, pores, and other geometries where water is subjected to negative Laplace pressure. Using a molecular model of water freezing on a hydrophilic substrate, it is found that heterogeneous ice nucleation rates exhibit a similar temperature increase at negative pressures as homogeneous ice nucleation. For pressures ranging from from 1 atm to −1000 atm, the simulations reveal that the temperature corresponding to the heterogeneous nucleation rate coefficient jhet (m−2 s−1) increases linearly as a function of negative pressure, with a slope that can be approximately predicted by the water density anomaly and the latent heat of fusion at atmospheric pressure. Simulations of water in capillary bridges confirm that negative Laplace pressure within the water corresponds to an increase in heterogeneous freezing temperature. The freezing temperature in the water capillary bridges increases linearly with inverse capillary height (1/h). Varying the height and width of the capillary bridge reveals the role of geometric factors in heterogeneous ice nucleation. When substrate surfaces are separated by less than approximately h = 20 Angstroms the nucleation rate is enhanced and when the width of the capillary bridge is less than approximately 30 Angstroms the nucleation rate is suppressed. Ice nucleation does not occur in the region within 10 Angstroms of the air-water interface and shows a preference for nucleation in the region just beyond 10 Angstroms. These results help unify multiple lines of experimental evidence for enhanced nucleation rates due to reduced pressure, either resulting from surface geometry (Laplace pressure) or mechanical agitation of water droplets. This concept is relevant to the phenomenon of contact nucleation and could potentially play a role in a number of different heterogeneous nucleation or secondary ice mechanisms.
ANALISIS KEMANDIRIAN DAN EFEKTIVITAS KEUANGAN DAERAH KABUPATEN DAN KOTA DI PROVINSI SUMATERA SELATAN SEBELUM DAN SESUDAH PANDEMI COVID-19
Authors: Alfansa Rayhan , Wibowo Puji
Published: March 2023

The presence of Covid-19 in the early 2000 shocked Indonesia in many aspects. The performance of regional governments in terms of of local budget management was questionable during the pandemic period. The purpose of this study is to analyze impact of Covid-19 pandemic to financial performance in regencies and cities under South Sumatera jurisdiction. This research is analysing the differences of financial independence ratio and financial effectiveness ratio of districts and cities in South Sumatera between before and post-COVID-19 pandemic period. The type of this research is quantitative research in form of comparative research by using saturated sampling. The data collection method which used by author are library method and non-behavioral observation method. The data process method which used by author are analysis method with using t-test and sample collection method. The final results of this research are there are no significant differences for financial independence ratio and there are significant differences for financial effectiveness ratio of districts and cities in South Sumatera between before and after COVID-19 pandemic
Pengaruh ROA, ROE, NPM Terhadap Pertumbuhan Laba Pada Perusahaan Sektor Konstruksi Dan Bangunan Di Bursa Efek Indonesia (BEI)
Authors: Wili Handayani  , Irwan Hermawan  , Meutia Riany
Published: March 2023

Riset ini bertujuan untuk membuktikan return on assets, return on equity, net profit marginada pengaruh terhadap pertumbuhan laba pada sektor konstruksi dan bangunan yang terdaftar di Bursa Efek Indonesia 2016-2020. Data yang digunakan pada penelitian ini yaitu data sekunder sebanyak 45 sampel. Pengujian dan analisis data menggunakan regresi berganda dengan program SPSS. Penelitian ini memberikan hasil bahwa return on assets dan net profit margin secara parsial berpengaruh signifikan terhadap pertumbuhan laba. Sedangkan return on equity secara parsial tidak mempunyai penngaruh signifikan terhadap pertumbuhan laba. Namun, secara simultan return on assets, return on equity, net profit margin berpengaruh signifikan terhadap pertumbuhan laba
Satisfaction of Cooperative Services in The Digital Era
Authors: Sinulingga Gairah , Sutisno Joko , Suryo Hutomo Adi , Sutoto Agung
Published: March 2023

The Digital Era is when all activities become efficient and effective by utilizing the results of technological developments in the economy. Cooperatives as an economic-institutions can also take advantage of business applications to improve service quality, which impacts in-creasing member satisfaction. This study aims to produce information in the form of a more in-depth explanation of the effect of service quality on the satisfaction level of Cooperative Members. And obtain the results of processed data about how much influence service quality has on the level of satisfaction of Cooperative Members in Depok Municipality. The research method used in this study, the data obtained, both quantitative and qualitative in nature, were examined using a descriptive verification method, namely by interviewing and giving questionnaires to 87 respondents, members using the probability sampling method, as a means to obtain accurate data. Data is processed using the SPSS 22.00 series application. The study results the show that service quality influences the level of satisfaction with a complete presentation of 22.1%, and other factors influence the rest at 77.9%. Correlation analysis obtained an R-value of 0.470. It can be concluded that there is a relationship between Service Quality and Member Satisfaction Level. The regression equation yields Y = 2.206 + 0.453X; it is supposed that if there is no Service Quality, then the Member Satisfaction Level remains at 2.206. The hypothesis is proven by the regression coefficient of the independent variable with the t-test; the result is that the coefficient of variable X on transac-tion satisfaction is significant. It can be seen that the value of the count of 4,905 ttable1,988, eye H0 rejected and H1 accepted.
La complementariedad diferenciada. Acerca del modo de relación de la totalidad de lo (in)condicionado en la lógica transcendental de Kant
Authors: Sepúlveda Zambrano Pedro Horacio
Published: March 2023

Este artículo presenta el modo de relación de la totalidad de lo condicionado y lo incondicionado en la lógica transcendental de Kant. Para ello el argumento reconstruye los elementos que abren el tratamiento de la dialéctica transcendental en la Crítica de la razón pura, es decir, la apariencia ilusoria y las Ideas de la razón. Este modo de leer la doctrina de las síntesis transcendentales de lo condicionado y lo incondicionado exhibe la tesis de la complementariedad diferenciada entre ambas regiones, dando a cada una su derecho, lugar y misión.
Temor y temblor, o la singularidad del silencio
Authors: Parcero Oubiña Oscar
Published: March 2023

El presente trabajo ofrece una lectura de la obra de Kierkegaard Temor y temblor en la que, por medio de los ejemplos de filosofía que en ella se contraponen, se pone de manifiesto cómo la reivindicación de la singularidad constituye el centro de gravedad del texto. Este contenido central de la obra debe entenderse juntamente con la dialéctica de palabra y silencio que formalmente la determina. A partir del reconocimiento de la centralidad de la voz frente a la imposibilidad de la visión, se muestra cómo el pseudónimo Johannes de silentio, en su encuentro con la figura de Abraham, acalla toda especulación sobre la fe del patriarca al tiempo que da la palabra a la filosofía para que esta pueda decir lo que comporta la paradoja de la fe, a saber, la singularidad del individuo, cuyo sentido es ético, si bien descansa sobre una transcendencia que remite a lo religioso.
Dialéctica de la autoconciencia infinita y crítica pura en Bruno Bauer
Authors: Magnet Colomer Jordi
Published: March 2023

Con la obra de los jóvenes hegelianos (Junghegelianer) concluye el período clásico de la filosofía alemana. Bruno Bauer (1809-1882) fue uno de sus máximos exponentes, considerado en muchos aspectos como mentor del movimiento. En el primer apartado del presente artículo, se contextualiza la figura de Bauer en el trasfondo de las disputas generadas en el seno de la escuela hegeliana. A continuación, se analizan con mayor detenimiento dos nociones centrales en su pensamiento, especialmente durante el período comprendido entre 1829 y 1848: su dialéctica de la autoconciencia infinita (unendlichen Selbstbewußtsein) y la forma adoptada por su crítica pura.
The Study of Abraham Ibn Daud in the Past Three Decades: What Do We (Not) Know?
Authors: Fontaine Resianne
Published: March 2023

Las últimas tres décadas han sido testigos de un nuevo y vívido interés en Ibn Daud. La bibliografía en la entrada dedicada a este autor en la Stanford Encyclopedia of Philosophy revela que muchos estudios sobre Abraham Ibn Daud, así como nuevas ediciones de sus escritos, se han publicado entre 1990 y principios de la década de 2020. El objetivo de este artículo es hacer un balance de los resultados de la nueva investigación y revisar cómo se ha avanzado en nuestro conocimiento de este autor multifacético en las últimas décadas y detectar dónde hay todavía lagunas en nuestro conocimiento de su obra. Aunque voy a abordar varios aspectos de la vida de Ibn Daud, sus actividades y la recepción de sus obras, mi enfoque se va a centrar en los estudios de su trabajo filosófico.
Presencia y corporeidad en la antropología de Julián Marías
Authors: Irias Alfaro Bryan Jesús
Published: March 2023

El objetivo de este trabajo es analizar el concepto de corporeidad desde la filosofía antropológica de Julián Marías, además de observar cómo dicho concepto esté relacionado en manera directa con la teoría de la circunstancia de José Ortega y Gasset. Este artículo pretende mostrar la novedad de una filosofía de la presencia como manifestación la estructura empírica de la vida humana. Para llevar adelante esta tesis el escrito está divido en dos partes: la primera da cuenta de la corporeidad en el pensamiento antropológico mariasiano, y la segunda, que es la novedad de este trabajo, es observar cómo desde el concepto de presencia personal se puede conocer la totalidad realidad de la persona humana.
Las ideas epistemológicas de Francisco Fernández Buey como base para la tercera cultura
Authors: Martínez Solás Sebastián
Published: March 2023

En este artículo se presentan las reflexiones epistemológicas del filósofo Francisco Fernández Buey (1943-2012), las cuales, han estado continuamente presentes en la obra del autor al menos desde la publicación en 1991 de La ilusión del método, y culminan en su obra póstuma Para la tercera cultura (2013) en una apuesta por la complementariedad entre ciencias positivas y reflexión humanística. Partiendo de un marxismo heterodoxo tanto en el plano ético-político como en el epistemológico, Fernández Buey apuesta por una idea de ciencia alejada del positivismo, a la vez que critica las filosofías contrarias a aquella en la medida en que la consideran como un conocimiento meramente reductor de una realidad que no puede ser aprehendida por la ciencia. Desde el concepto de dialéctica de Manuel Sacristán; el reconocimiento a la figura de Einstein como ejemplo de científico que no renuncia a otros modos de conocimiento; y la reflexión sobre la filosofía de la ciencia en la segunda mitad del siglo XX, el autor nos muestra la necesidad de un diálogo entre cultivadores de la ciencia y las humanidades para afrontar los desafíos del siglo XXI.
Peran Orang Tua Terhadap Pendidikan Karakter Bagi Anak Generasi Alpha Dalam Menghadapi Era Metaverse
Authors: Parai' Nelsi
Published: March 2023

Dunia pendidikan anak masa kini telah menghadapi tantangan yang begitu sulit karena telah menghadapi era digital – era metaverse. Metaverse adalah sebuah rancangan yang menggabungkan antara dunia nyata dengan dunia digital  dalam artian bahwa dalam dunia digital (metaverse) orang dari berbagai tempat dapat bertemu untuk saling berinteraksi menggunakan teknologi virtual.  Dengan adanya metaverse seharusnya dapat  memperluas dan memberi peluang  bagi generasi alpha untuk produktif dan kreatif. Namun berbeda dengan kenyataan yang terjadi dalam kehidupan anak generasi alpha yang hidup dalam era metaverse merka mengalami kemerosotan karakter sehingga terjadi banyak penyimpangan moral dan etika.  Artikel ini mendeskripsikan pengaruh orang tua dalam menanankan pendidikan karakter dengan tujuan untuk menunjukkan bahwa orang tua mempunyai tanggungjawab besar yang begitu berpengaruh dalam proses pendidikan karakter anak supaya menjadi generasi yang berkualitas meskipun anak telah berada dalam situasi digitalisasi yang tidak dapat dihindari yakni era metaverse  Dalam penulisan artikel ini menggunakan metode deskriptif,  kajian pustaka  dan juga pengamatan sambil mengobservasi fakta yang terjadi, hal tersebut yang deskripsikan penulis sehingga masalah kemerosotan karakter bagi generasi alpha bisa ditemukaan Faktor penyebab terjadinya kemerosotan karakter bagi anak generasi allpha akan menjadi patokan bagi orang tua untuk mengawasi perilaku anaknya Berdasarkan penelitian yang dilakukan, penulis mengemukakan beberapa  faktor trjadinya perubahan karakter bagi anak generasi A yaitu kurangnya edukasi orangtua kepada anaknya karena sibuk dengan urusan duniawi sehingga melupakan tanggungjawabnya kepada anak meraka  dan orang tua hanya memenuhi keinginan anaknya secara bebas seperti pemberian gadget tanpa adanya kontrol dalam penggunaan.
Pengaruh Partisipasi Masyarakat, Kompetensi Aparat, Sistem Keuangan Desa dan Pengawasan terhadap Akuntabilitas Pengelolaan Keuangan Desa di Kabupaten Luwu Timur
Authors: Ahmad Sulaiman , Sapar Sapar
Published: March 2023

Penelitian ini bertujuan untuk menganalisis pengaruh partisipasi masyarakat (X1), kompetensi aparat (X2), sistem keuangan desa (X3) dan pengawasan (X4) terhadap akuntabilitas pengelolaan keuangan desa (Y). Metode yang digunakan adalah metode kuantitatif dengan menyebarkan angket kepada aparat desa dari 124 desa di Kabupaten Luwu Timur. Hasil distribusi angket tersebut total 95 desa dilakukan pengukuran menggunakan skala likert dan pengujian penelitian dengan Structural Equation Modeling (SEM) menggunakan aplikasi Smart-PLS. Hasil penelitian ini menunjukkan bahwa hipotesa pertama menyatakan nilai tHitung 1.269 < tTable 1.986 dengan PValue sebesar 0,205 > 0,05 artinya Partisipasi Masyarakat berpengaruh positif namun tidak signifikan terhadap Akuntabilitas Pengelolaan Keuangan Desa. Hipotesa kedua nilai tHitung 2,314 > tTabel 1.986 dengan PValue 0,021 < 0,05 artinya Kompetensi Aparat berpengaruh positif dan signifikan terhadap Akuntabilitas Pengelolaan Keuangan Desa. Hipotesa ketiga nilai tHitung 0,190 < tTabel 1.986 dengan PValue 0,849 > 0,05 artinya Siskudes berpengaruh positif namun tidak signifikan terhadap Akuntabilitas Pengelolaan Keuangan Desa. Hipotesa keempat nilai tHitung 3,203 > tTabel 1,972 dengan PValue 0,001 < 0,05 artinya Pengawasan berpengaruh positif dan signifikan terhadap Akuntabilitas Pengelolaan Keuangan Desa. Sehingga disarankan agar pemerintah desa memaksimalkan Partisipasi Masyarakat dan pemanfaatan Siskeudes serta mempertahankan Kompetensi Aparat dan Pengawasan agar Akuntabilitas Pengelolaan Keuangan Desa di Kabupaten Luwu Timur semakin baik.
Gambaran Kepatuhan Mengkonsumsi Obat Pada Penderita Hipertensi di Puskemas Pekauman, Kota Banjarmasin Kalimantan Selatan Tahun 2022
Authors: Jamini Theresia
Published: March 2023

Hipertensi adalah salah satu penyebab utama kematian dini di seluruh dunia. Peningkatan angka kejadian hipertensi berdampak pada penurunan kualitas hidup dari penderitanya. Tidak hanya berdampak pada penurunan kualitas hidup penderitanya, tetapi juga dapat berdampak pada perubahan sistem tubuh manusia bahkan dapat menyebabkan kematian. Salah satu penyebabnya adalah ketidakpatuhan penderita dalam mengkonsumsi obat hipertensi. Penderita hipertensi harus selalu rutin minum obat hipertensi dan tidak boleh putus obat apapun alasannya. Obat hipertensi sifatnya adalah memperlebar pembuluh darah sehingga dapat memperlancar peredaran darah yang dapat mencegah peningkatan tekanan darah pada penderitanya, Oleh sebab itu  diharapkan penderita rutin mengkonsumsi obat hipertensi. Kepatuhan dalam mengkonsumsi obat hipertensi menjadi sangat penting bagi penderita hipertensi.  Penelitian ini bertujuan mengidentifikasi bagaimana gambaran kepatuhan mengkonsumsi obat pada penderita hipertensi di Puskesmas Pekauman, Kota Banjarmasin, Kalimantan Selatan, Tahun 2022. Penelitian ini merupakan jenis penelitian kuantitatif dengan menggunakan rancangan penelitian deskriptif. Desain penelitiannya adalah cross sectional. Instrumen yang digunakan adalah lembar kuesioner. Responden penelitian berjumlah 30 orang yang dipilih dengan menggunakan teknik accidental sampling. Hasil analisa penelitian yang dapat diperoleh dari 30 responden adalah bahwa  terdapat 19 responden (63,3%) patuh dalam mengkonsumsi obat hipertensi dan terdapat 11 responden (36,7%)  tidak patuh mengkonsumsi obat hipertensi. Kepatuhan penderita hipertensi dalam mengkonsumsi obat hipertensi di Puskesmas Pekauman Kota Banjarmasin Tahun 2022 adalah mayoritas dalam kategori patuh.
bienestar psicológico y COVID 19 en estudiantes universitarios
Authors: Portilla Villarreal Jefferson , Casa Vera Paola , León Ron Veronica , Pabón Karina , Narváez Olmedo Gabriela
Published: March 2023

El estudio busca identificar los efectos que tuvo la pandemia por COVID 19 en el bienestar psicológico de la población universitaria. Se tomó un enfoque cuantitativo de diseño descriptivo, de tipo transversal, participaron 2083 estudiantes de la Universidad Técnica del Norte de los cuales 722 pertenecen al género masculino y 1361 al femenino, fueron evaluados con la Escala de Bienestar Psicológico de Ryff, que consta de 39 ítems distribuidos en 6 dimensiones. Los datos obtenidos se analizaron con el Software SPSS. Se encontró que el mayor número de estudiantes poseen un bienestar psicológico alto, siendo los hombres quienes mostraron una media de 123,40 a diferencia de una media de 119,36 en las mujeres dentro de una puntuación máxima de 174. En las dimensiones, la autonomía se ubicó como la mejor puntuada por los estudiantes y la autoaceptación la menor puntuada. Los resultados señalan que un gran porcentaje de estudiantes no presentan efectos profundos en la salud mental debido al confinamiento por la pandemia, pero, del grupo afectado, el género femenino evidenció mayor vulnerabilidad.
REASONS FOR NON-USING FAMILY PLANNING METHOD IN ONE OF DEVELOPING COUNTRIES
Authors: Urindwanayo Desire , Engelbrecht Charlotte
Published: March 2023

The present paper is discussing the reason for non-using of family planning. In this study, a quantitative descriptive design with a positivist paradigm guided the whole research process. Two levels of sampling were done. The first was random sampling for the selection of healthcare centres where five healthcare centres were selected out of a total of eighteen. The second level was probability sampling with a systematic strategy, which was used to select the participants at healthcare centres. A total of 137 women volunteered to participate in the study and completed an anonymous questionnaire. The authorization to carry out the research was obtained from Nyagatare District and five healthcare centres. The research was approved by the University of KwaZulu-Natal Ethics Committee. The gathered data were analyzed using SPSS version 19.
NUMERICAL METHOD FOR ESTIMATING FLOW PATTERN AROUND CONSECUTIVE HOCKEY-SHAPED SPUR DIKE WITH USING COMPUTATIONAL FLUID DYNAMIC
Authors: Hooshmand Aini Ali
Published: March 2023

Using the Dike is an indirect method for controlling coastline erosion based on the modification of the flow pattern. The construction of this structure is with the aim of diverting the flow from erodible River coastline or establishing the appropriate route for directing the flow and sometimes for required depth of shipping. This paper uses a numerical model to study flow patterns around the Consecutive Hockey-shaped Spur Dike. Firstly, the geometric model and meshing of the structure are generated in GAMBIT software and then the model is solved with the software FLUENT. In this paper, we have chosen k-ε as turbulence model. The results of the analysis are presented as the flow pattern in the dike and the distribution of velocity counter in X and Y directions.
RELEVANCE OF SCHOOL RELATED FACTORS TO THE JOB PLACEMENT OF ENGINEERING GRADUATES
Authors: H. Chavez Nemy , L. De Castro Evelyn , C. Camello Nestor , A. Dolot Joselito , M. Laguador Jake
Published: March 2023

This study aimed to determine the relevance of school related factors in terms of Faculty and Instruction, Student Services, Organization and Administration, Community Extension, Linkages & Research to the job placement of Engineering graduates. Descriptive type of research as utilized in the study. Results revealed that the engineering graduates believed that community extension, linkages and research have the highest relevance to their job placement followed by student services, faculty and instruction while the organization and administration obtained the least mean score. Employees of higher education institutions should be aware of the image they project while dealing with the students and they should keep on reminding their value as part of the students’ development of future engineers and professionals.
AN ECONOMETRICS INVESTIGATION INTO THE IMPACT OF UNEMPLOYMENT ON ECONOMIC GROWTH IN NIGERIA (1981-2015)
Authors: Matthew Abula, , Daddy Mordecai Ben
Published: March 2023

This study investigated the impact of unemployment on economic growth in Nigeria (1981- 2015) adopting the Ordinary Least Square technique (OLS), Augmented Dickey-Fuller test, Co-integration, Vector Error Correction Mechanism (VECM) and the Granger Causality tests. The regression results revealed that unemployment and inflation have negative and insignificant impact on economic growth, while government expenditure has a significant positive impact on economic growth in Nigeria. The computed R-squared implied that about 95% of the systematic variation in economic growth is explained by the unemployment, government expenditure and inflation and indicated that the model has a good fit. The result from the Johansen Co-Integration test revealed a long-run co-movement between the dependent variable, economic growth and the three independent variables, unemployment, government expenditure and inflation. The vector error correction coefficient for LNRGDP meets the apriori expectation of a negatively singed coefficient and this implied that 3.7976% of the errors are corrected in the long-run and as such there is a convergence. Granger Pairwise causality test result revealed that government expenditure granger causes real GDP at 5% level of significance, while none of the other variables granger caused the other. Hence, the study recommended that the activities of the government in promoting economic growth in the country should be geared towards promoting employment for the people, particularly in areas of agriculture, small and medium scale businesses and also, government expenditure in the economy should be increased as it brings about economic growth and would result in increased employment rate in the long-run.
INTEGRATED PARAMETER CONTROL SYSTEM FOR DRIVING MOTOR MOBILE INTERNET
Authors: Quan Ming Li
Published: March 2023

The brushless dc motor is a new kind of stepless variable speed motor, convenient maintenance, high efficiency and high performance is excellent, has on many occasions to replace other kinds of motors. Therefore, the further research of brushless dc motor has become a hot spot, has broad market prospects. In brushless dc motor as the research object, this paper designed a set of brushless dc motor based on TMS320F2812 DSP closed-loop variable frequency speed regulation system. On brushless dc motor speed control system of the basic composition, working principle, mathematical model and control strategy is commonly used, and on this basis of brushless dc motor double closed-loop control experiments, the results show that under the double closed loop control, brushless motor can run stable and reliable.
LASER ASSEMBLY AND PACKAGING OF A MEMS DEVICE
Authors: Wang Wei  , Jiang Li
Published: March 2023

Integration of 3-D devices, IC or MEMS, often requires a handle wafer which is removed before final packaging of the devices. This process usually uses lapping, chemical etch or high temperature heating to de-bond the handle wafer. A new technique to release a Pyrex handle wafer using laser ablation is presented. Pulsed energy, from a 248nm excimer laser is delivered transparently through the Pyrex handle wafer. This causes delamination of the bonded silicon structures from the handle wafer. This technique offers fast throughput at chip and wafer levels and protects the fragile and delicate active devices from harsh physical, chemicals and potential thermal stresses. We present a method wherein the handle wafer used in 3-D assembly of a MEMS device was released using laser micromachining. A Pyrex handle wafer rigidly supports anisotropically etched, through-silicon wafer, vertical mirrors during thermo-compression bonding to active MEMS parts. After this first thermo-compression bond, the Pyrex handle wafer was lifted off using laser ablation, leaving clearance for additional bond steps, which includes additional components and a package frame. Multiple Au-Au thermo-compression bonds of vertical surfaces onto a single MEMS chip were performed, to assemble and package 3-D MEMS devices.
SEPARATOR PROTOTYPE FOR FOUR TYPES OF OBJECTS BASED ON CANNY EDGE DETECTION METHOD
Authors: Christyono Yuli , Sumardi  , Sapitri Diah , Setiawan Iwan , Sofwan Aghus , Ajulian Ajub
Published: March 2023

The development of current technology makes easier for human beings in overcoming work. One of them is a selection of objects on industry. On a large-scale industry, the process of selection objects is done continuously, and it requires a high degree of accuracy. The work goes on for 24 hours unceasingly, which is hard for human. Therefore, it needs an instrument that works automatically to ease the selection process of objects. In this research, a prototype that separates objects based on shape is conducted. Shape recognition process utilizes canny edge detection method with microcontroller ATmega16 as a whole system controller. According to the testing result, the prototype can recognize and separate objects a circle, square, rectangular, and equilateral triangles. The ratio roundness (metric) values for circle, square, rectangular, and equilateral triangle are 1.00-0.90, 0.90-0.83, 0.81-0.70, and <0.70, respectively. Moreover, the level of success for separating circle object, square object, rectangular object, equilateral triangle object, and whole system are 100%, 80%, 100%, 100%, and 85%, severally.
AN APPLIED METHOD FOR ESTIMATING THE AMOUNT OF WATER EXCHANGE BETWEEN THE SEASONAL RIVERS AND AQUIFER, CASE STUDY: ZAYANDEHROUD RIVER IN THE CITY OF ISFAHAN
Authors: H. Karami Gholam , Fazileh Farid , Ajalloeian Rassoul
Published: March 2023

In most cases, the rivers that flow in the alluvial aquifers are hydraulically connected to them. So, in such areas, it is essential to determine the relationship between the river and the aquifer. In this study, hydraulic connection between alluvial aquifer of Isfahan city and Zayandehroud River are evaluated. The main recharge source of this alluvial aquifer is Zayandehroud River. In recent years from March to November, due to the shortage of water and consumption of whole of the river flow rate in the upstream of the Isfahan city, the flow to the Isfahan region is disconnected. Therefore, the November and December are those months which are respectively the end of the dry period and the start of the river flow period. Using the groundwater isopotential maps of the November and December, 2015, the hydraulic connection between the river and aquifer during the dry and wet period was compared. The obtained results show that during the period of water flow in the river, there is an effective connection between river and aquifer. In most places the river recharges the aquifer. In some parts of aquifer in the south of the river, considerable cones of depression caused by heavy pumping have been created which changed the normal pattern of groundwater flow to a forced recharge from the river. Most recharge to the Isfahan aquifer by the river occurs in the western part of the city till the region of Khajo Bridge. The amount of this recharge is about 55028 m3/day.
FUSING STEREO IMAGES INTO ITS EQUIVALENT CYCLOPEAN VIEW
Authors: koyuncu Baki , Abdulwahhab Ali h.
Published: March 2023

Image fusion is a technique of intertwining at least two pictures of same scene to shape single melded picture which shows indispensable data in the melded picture. Picture combination system is utilized for expelling clamor from the pictures. Commotion is an undesirable material which crumbles the nature of a picture influencing the lucidity of a picture. Clamor can be of different kinds, for example, Gaussian commotion, motivation clamor, uniform commotion and so forth. Pictures degenerate some of the time amid securing or transmission or because of blame memory areas in the equipment. Picture combination should be possible at three dimensions, for example, pixel level combination, highlight level combination and choice dimension combination. There are essentially two kinds of picture combination methods which are spatial area combination systems and transient space combination procedures. (PCA) combination, Normal strategy, high pass sifting are spatial area techniques and strategies which incorporate change, for example, Discrete Cosine Transform, Discrete wavelet change are transient space combination strategies. There are different techniques for picture combination which have numerous favorable circumstances and detriments. Numerous procedures experience the ill effects of the issue of shading curios that comes in the intertwined picture shaped. Also, the Cyclopean One of the most astonishing properties of human stereo vision is the combination of the left and right perspectives of a scene into a solitary cyclopean one. Under typical survey conditions, the world shows up as observed from a virtual eye set halfway between the left and right eye positions. The apparent picture of the world is never recorded specifically by any tangible exhibit, however developed by our neural equipment. The term cyclopean alludes to a type of visual upgrades that is characterized by binocular dissimilarity alone. He suspected that stereo-psis may find concealed articles, this may be helpful to discover disguised items. The critical part of this examination when utilizing arbitrary dab stereo-grams was that uniqueness is adequate for stereo-psis, and where had just demonstrated that binocular difference was vital for stereo-psis.
RESEARCH ON CAR REVERSING RADAR SYSTEM BASED ON ULTRASONIC
Authors: Xiaoqi Jiang , Mingming Zhang , Jiaqi Lu , Qianliang You
Published: March 2023

Due to the increasing number of private cars in today's society, there are a lot of safety problems in car reversing. This paper proposes a research program of ultrasonic ranging car reversing radar system with higher accuracy and better warning effect. According to the principle of ultrasonic ranging, the AT89C51 single-chip microcomputer is selected as the core circuit, and the anti-interference error processing is adopted in the processing of the single-chip microcomputer to solve the multiple measurement, the transmission time interval and the dead zone measurement problem of the ultrasonic ranging. Car reversing radar system based on ultrasonic ranging adopt transmitting and receiving circuit, will determine the time difference in the single chip microcomputer. the results are sent to the digital display circuit and voice broadcast circuit. Finally, it is verified by experiments that after ultrasonic error measurement adopts error processing, under the complicated environmental conditions, the accuracy of ranging is higher, the number of false alarms is reduced, and the device has high reliability and practicability.