bluuebunny/crossref_metadata_2025 huggingface dataset:
Weighted gene co-expression network analysis to identify key modules and hub genes related to hyperlipidaemia
Authors: Liao Fu Jun , Zheng Peng-Fei , Guan Yao-Zong , Li Wei
Published: August 2020

Background: The purpose of this study was to explore the potential molecular targets of hyperlipidaemia and the related molecular mechanisms.Methods: The microarray data set of GSE66676 obtained from patients with hyperlipidaemia was downloaded. The weighted gene co‑expression network (WGCNA) analysis was used to analyze the gene expression profile and royalblue module was considered as the highest correlation. Gene Ontology (GO) functional and Kyoto Encyclopedia of Genes and genomes (KEGG) pathway enrichment analyses were implemented for the identification of genes in the royalblue module using the Database for Annotation, Visualization and Integrated Discovery (DAVID) online tool (version 6.8; http://david.abcc.ncifcrf.gov). A protein-protein interaction (PPI) network was established by using the online STRING tool. Then, several hub genes were identified by the MCODE and cytoHubba plug-ins in Cytoscape software.Results: The significant module (royalblue) identified was associated with TC, TG and Non-HDL-C. GO and KEGG enrichment analyses revealed that the genes in the royalblue module were associated with carbon metabolism, steroid biosynthesis, fatty acid metabolism and biosynthesis of unsaturated fatty acids pathways. SQLE (degree = 17) was revealed as key molecules that associated with hypercholesterolemia (HCH) and SCD was revealed as key molecules that associated with hypertriglyceridemia (HTG). Meanwhile, RT-qPCR analysis also confirmed the above results based on our HCH/HTG samples.Conclusions: SQLE and SCD are related to hyperlipidaemia, SQLE/SCD may be new targets for cholesterol-lowering or triglyceride-lowering therapy, respectively.
A Comparison of the Autistic Behavior Checklist and the Childhood Autism Rating Scale for Suspected Autism in a Large Chinese Sample
Authors: Chu Jiahui , Bian Fang , Yan Ruiying , Li Yanlin , Cui Yonghua , Li Ying
Published: August 2020

Autism is the most common clinical developmental disorder in children. The Childhood Autism Rating Scale (CARS) and Autistic Behavior Checklist (ABC) are the most commonly used assessment scales for diagnosing autism. The aim of this study is to compare the diagnostic validities of CARS and ABC based on a large Chinese sample. A total of 474 children with suspected autism spectrum disorder (ASD) were screened by CARS and ABC. Receiver operating characteristic (ROC) curve analysis was performed and it showed that the area-under-the-curve values of CARS is higher than ABC significantly (p < 0.05) and the suggested cutoff values of CARS and ABC were 34 and 67, respectively. It indicated that CARS is superior to ABC in the Chinese population with suspected ASD.
Production and identification of two antifungal terpenoids from the Posidonia oceanica epiphytic Ascomycota Mariannaea humicola IG100
Authors: Botta Lorenzo , Saladino Raffaele , Barghini Paolo , Fenice Massimiliano , Pasqualetti Marcella
Published: August 2020

Background
Marine fungi are an important repository of bioactive molecules with great potential in different technological fields, the annual number of new compounds isolated from marine fungi is impressive and the general trend indicates that it is still on the rise. In this context, the antifungal and antimicrobial activity of the marine strain Mariannaea humicola IG100 was evaluated and two active terpenoids were isolated and characterized.
Methods
Preliminary screening of activity of marine strain IG100 was carried out by agar plug diffusion methods against fungal (P. griseofulvum TSF04) and bacterial (Bacillus pumilus KB66 and Escherichia coli JM109) strains. Subsequently, inhibition tests were done by using the cultural broth and the organic extract (ethyl acetate, EtOAc) by the agar well diffusion methods. The main active fractions were identified and tested for their antifungal activity against P. griseofulvum TSF04 in a 24 wells microplate at different concentrations (1000, 100, 10 and 1.0 µg/mL). Two active compounds were characterized and their relative MIC measured by the broth micro-dilution methods in a 96-well microplate against A. flavus IG133, P. griseofulvum TSF04, and T. pleuroticola IG137.
Results
Marine strain IG100 presented significant antifungal activity associated to two active compounds, the terpenoids terperstacin 1 and 19-acetyl-4-hydroxydictyodiol 2. Their MIC values were measured for Aspergillus flavus (MIC of 7.9 µg/mL and 31.3 µg/mL for 1 and 2, respectively), P. griseofulvum (MIC of 25 µg/mL and 100 µg/mL for 1 and 2, respectively) and T. pleuroticola (MIC > 500 µg/mL and 125 µg/mL for 1 and 2, respectively). They showed a rather good fungistatic effect.
Conclusions
In this study, the first marine strain of M. humicola (IG100) was investigated for the production of bioactive molecules. Strain IG100 produced significant amounts of two bioactive terpenoids, terperstacin 1 and 19-acetyl-4-hydroxydictyodiol 2. The two compounds showed significant antifungal activities against A. flavus IG133, T. pleuroticola IG137 and P. griseofulvum TSF04. Compound 2 was identified for the first time in fungi.
A Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of Shuilu Erxian Dan in Treating Diabetic Kidney Disease
Authors: Wu Tingchao , Yue Rensong , He Mingmin
Published: August 2020

Background and objective:

Recent years, some Chinese scholars have applied Shuilu Erxian Dan (SED) to the treatment of treating diabetic kidney disease (DKD) and achieved well curative effect. However, these studies are mostly limited to clinical observation. This study aimed to explore the molecular mechanisms of SED in treating DKD.
Methods

The active components of SED were retrieved in TCMSP database and BATMAN-TCM database, and the herbal targets were obtained by drugbank database and SwissTargetPrediction platform. The gene expression data of DKD patients were downloaded from GEO database and analyzed to obtain DKD-related targets. The ingredient-target network and the PPI network were constructed by Cytoscape software. The clusterProfiler package of R software is used for bioinformatic analysis. Molecular docking was further applied to verify the interaction between compounds and targets by Autodock Vina software.
Results

610 differential expressed genes of DKD patients were obtained, and 29 potential targets of SED against DKD were screened out (including PPTGS2, FABP3, HSD17B2, FABP1, HSD11B2, CYP27B1, JUN, UGT2B7, VCAM1, CA2, MAOA, MMP2, CXCR1, SLC22A6, EPHX2, SLC47A1, FOS, EGF, CCL2, COL3A1, GSTA1, GSTA2, HSPA1A, DAO, ALDH2, ALB, GPR18, FPR2, and LPL). All the active ingredients in SED can act on the DKD-related targets, among which quercetin, Ellagic acid, and kaempferol may be the key active compounds. SED may play a therapeutic role in DKD by regulating pathways including “Fluid shear stress and atherosclerosis”, “AGE − RAGE signaling pathway in diabetic complications” and “IL-17 signaling pathway”.
Conclusion

This study suggests that the mechanism of SED treating DKD is a complex network with multi-target and multi-pathway, which provides a reference for future experimental studies.
Mortality Data in Mechanically Ventilated COVID-19 patients admitted to ICU: A Retrospective Study in Brooklyn
Authors: Patti Ravi Karan , Duarte Claudia De Araujo , Dalsania Nishil , Thawani Rajat , Sinha Ankur , Gomes Bruno Augusto De Brito , Silver Michael , Seneviratne Chanaka , Somal Navjot , Kupfer Yihak
Published: August 2020

Background: High mortality rates are predominant even in COVID-19 patients requiring minimal supportive therapy, with a short-coming of data on COVID-19 patients requiring mechanical ventilation.Objectives/Design: We performed a single-center, retrospective, cohort study at a tertiary care, community-based teaching hospital with patient who required invasive mechanical ventilatory support and were COVID-19 positive. All patients were treated according to the ARDSnet protocol. The primary outcome was overall mortality, and secondary outcome was successful extubation.Results: A total of 72 COVID-19 positive intubated patients were included. Twenty-six (66.6%) patients died within the first 15 days of hospital admission; thirty-eight (52.7%) died within 28 days, and thirty-nine (54.2%) died within 29 days. A total of 22 patients (30.5%) were successfully extubated. 15 patients (20.8%) who required reintubation or could not be extubated further underwent tracheostomy.Conclusions: Mortality of critically ill COVID-19 patients requiring mechanical ventilatory support is high, our observed mortality rate (54.2%) was significantly lower than currently published reports. We believe our rate to be a consequence of early intubation in conjunction with adherence to ARDSnet protocol. We also observed patients with hyperlipidemia, higher CRP, renal failure, or those requiring vasopressor use had worse outcomes.
Blood biomarkers for assessing headaches in healthcare workers after wearing biological personal protective equipment in a COVID-19 field-hospital
Authors: Martín-Rodríguez Francisco , Rubiales Raquel M. Portillo , Millán Laura N. Fadrique , Rodríguez Virginia Carbajosa , Sanz-García Ancor , Herrera Gabino Mozo , Ortega Guillermo J. , Ballester Esther Durá , Villamor Miguel Ángel Castro , Izquierdo Raúl López
Published: August 2020

The consequences of wearing biosafety equipment by healthcare professionals during their work and the prediction of such consequences need to be assessed. To analyze the role played by different blood biomarkers in predicting the appearance of headaches in healthcare workers wearing personal protective equipment (PPE) in a COVID-19 treatment unit, a Prospective cohort study of 38 healthcare workers from a convalescence unit of patients with COVID-19 in a field hospital was performed during April 2020. Blood analysis was carried out before the start of the 4 hours shift of the volunteers equipped with PPE. After decontamination, there were asked if they had suffered from headache, obtaining the binary outcome. This study included 38 participants with a median age of 29 years (25th-75th percentile: 26-44 years old), 73.7% female (28 cases). 44.7% (17 cases) had a headache after wearing PPE for 4 hours. The baseline creatinine value reflected a specific odds ratio in the regression model of 241.36 (95% CI: 2.50-23,295.43; p=0.019), and an AUC of 0.737 (95%CI: 0.57-0.90; p<0.01). Blood creatinine is a good candidate for predicting the appearance of a de novo headache in healthcare workers after wearing PPE for 4 hours in a COVID – 19 unit.
Certain regulatory and efficiency issues of public utility companies in Budapest
Authors: Lentner Csaba , László Vasa , Petronella Molnár
Published: August 2020

Capital cities of the world are usually characterized by a concentration of the majority of the population and most of the public administration and economic life. Therefore, the efficiency and quality of public service delivery in their administrative territories make a difference. The study examines public service companies in Budapest, Hungary’s capital, with the focus on their sectors of activity to describe their system, which may provide good foundations for a prospective international comparison.This study explores sector-oriented reports of state- and municipally-owned public utility companies providing services within the administrative territory of Budapest and evaluates them in terms of total assets, finance, profitability and efficiency. The study looked for an answer to the question of how the tighter state regulation and control adopted after 2010 affected their management, and what influence the price regulation of consumer public utility charges, imposed since 2013, had on companies’ activities.
O MARCO DA CARTA DEMOCRÁTICA INTERAMERICANA E SUA INTERPRETAÇÃO NO PROCESSO DE IMPEACHMENT DA PRESIDENTE DILMA ROUSSEFF: REPENSANDO A DEMOCRACIA
Authors: Teixeira Marques Verônica , Galvão Vivianny
Published: August 2020

Após repensar a categoria de democracia a partir dos teóricos clássicos e contemporâneos, como analisar a posição da CoIDH, acerca da solicitação de opinião consultiva feita pelo Secretário Geral da Organização dos Estados Americanos, a respeito do processo de impeachment da Presidente Dilma Rousseff? O objetivo deste artigo foi, por meio de um estudo de caso, repensar os contornos da democracia. Verificou-se que a CoIDH negou o prosseguimento do pedido acerca da legitimidade do impeachment por unanimidade, ou seja, a Corte “opinou por não opinar”. Levando-se em consideração que o sistema interamericano considera a Carta como manifesto em favor da democracia representativa nas Américas propondo um conceito de democracia que transcende a ideia de democracia eleitoral, a decisão da Corte respeita as bases jurídicas da legislação internacional mas é contraditória à da transcendência democrática que vai além do voto. A metodologia utilizada foi qualitativa com método de estudo de caso.
A LEGITIMIDADE DA RECUSA DA TRANSFUSÃO DE SANGUE POR MOTIVOS RELIGIOSOS À LUZ DO DIREITO À SAÚDE NOS 30 ANOS DA CONSTITUIÇÃO
Authors: Resende José Renato Venâncio , Souza Alves Rodrigo Vitorino
Published: August 2020

A vida, a saúde e a liberdade religiosa são direitos fundamentais consagrados pela Constituição de 1988 e que devem ser igualmente protegidos. Entretanto, há situações em que eles podem entrar em (aparente) conflito, como quando, por exemplo, um cidadão nega-se a receber transfusão sanguínea alegando motivos religiosos. Nestes casos, surgem alguns questionamentos bioéticos, médicos e jurídicos para os quais o Direito ainda não tem resposta definitiva, em especial no que tange a como o profissional da saúde deve proceder. A partir desse problema, o presente artigo busca entender, a partir do análise do direito à saúde, em quais casos a recusa à hemotransfusão pode ser legítima e como ela deve ser tratada.
Improving wastewater treatment plants operational efficiency and effectiveness through an integrated performance assessment system
Authors: Cassidy J. , Silva T. , Semião N. , Ramalho P. , Santos A. , Feliciano J.
Published: August 2020

Optimizing the efficiency of urban water systems is a growing concern for water utilities worldwide. Wastewater treatment plants (WWTP) are crucial in maintaining water quality and resource recovery in a world facing growing challenges such as climate change, water-energy-food nexus and the increase of legal requirements and users' expectations. Thus, adopting a performance assessment system (PAS) is of the utmost importance to assess operating conditions and to identify critical aspects of the WWTP which can negatively affect its effectiveness, efficiency and reliability. This paper presents the global and operational performance assessment of an urban WWTP and identifies improvement measures. The WWTP presented a good performance in terms of effectiveness and reliability. Nevertheless, in terms of efficiency, relevant improvement opportunities were identified, specifically in the sludge treatment phase and in terms of energy management. PAS was proven to be successful in the identification and prioritization of rehabilitation needs in a systematic way which will continuously improve the efficiency and effectiveness of the WWTP as well as to support asset management decisions regarding their upgrade and retrofit.
Адсорбция атомов I и VII групп на политипах карбида кремния
Authors: Давыдов С.Ю. , Посредник О.В.
Published: August 2020

Within the scope of the Haldane-Anderson model the estimates of charge transfer and adsorption energy for alkali metals and halogens atoms on the С- and Si-faces of 3С-, 6Н- and 4Н-SiC polytypes are obtained. Band and local states contributions to the formation of adatom’s charge and ionic and metallic parts of the adsorption energy are clarified.
Структурные и оптические характеристики ультрафиолетовых 4H-SiC-детекторов, облученных ионами аргона
Authors: Калинина Е.В. , Кудояров М.Ф. , Никитина И.П. , Иванова Е.В. , Забродский В.В.
Published: August 2020

Abstract The paper presents the results of a study of the effect of irradiation with heavy Ar ions on the structural and optical characteristics of 4H-SiC. It has been shown that as a result of already single irradiation with Ar ions with an energy of 53 MeV with a fluence of 1٠1010 cm-2, at least 2 powerful local regions with negative deformation prevail in the structure of silicon carbide. Along with this, a region with positive deformation is also observed in the structure. The formation of localized clusters with negative and positive deformations, along with the undisturbed matrix, is accompanied by the formation of linear type defects that partially relieve stresses in the structure. It is assumed that the resulting complex defect structure upon irradiation with Ar ions provides the effect of gettering of point defects and leads to the quantum efficiency of 4H-SiC UV photodetectors at the level of the initial samples.
Dynamics and Development of the COVID-19 Epidemic in the United States: A Compartmental Model Enhanced With Deep Learning Techniques
Authors: Deng Qi
Published: August 2020

Background

Compartmental models dominate epidemic modeling. Transmission parameters between compartments are typically estimated through stochastic parameterization processes that depends on detailed statistics of transmission characteristics, which are economically and resource-wise expensive to collect.

Objective

We aim to apply deep learning techniques as a lower data dependency alternative to estimate transmission parameters of a customized compartmental model, for the purpose of simulating the dynamics of the US coronavirus disease (COVID-19) epidemic and projecting its further development.

Methods

We constructed a compartmental model and developed a multistep deep learning methodology to estimate the model’s transmission parameters. We then fed the estimated transmission parameters to the model to predict development of the US COVID-19 epidemic for 35 and 42 days. Epidemics are considered suppressed when the basic reproduction number (R0) is less than 1.

Results

The deep learning–enhanced compartmental model predicts that R0 will fall to <1 around August 17-19, 2020, at which point the epidemic will effectively start to die out, and that the US “infected” population will peak around August 16-18, 2020, at 3,228,574 to 3,308,911 individual cases. The model also predicted that the number of accumulative confirmed cases will cross the 5 million mark around August 7, 2020.

Conclusions

Current compartmental models require stochastic parameterization to estimate the transmission parameters. These models’ effectiveness depends upon detailed statistics on transmission characteristics. As an alternative, deep learning techniques are effective in estimating these stochastic parameters with greatly reduced dependency on data particularity.
Biography of Beyza Boynudelik
Authors: Boynudelik Beyza
Published: August 2020

Bio + Image # 4
Effects of Biliteracy in Writing and Metacognition: Biliterates, Bilinguals, and Monolinguals
Authors: Ng Elaine
Published: August 2020

This quantitative study investigates metacognitive knowledge (i.e., knowledge about text characteristics and writing strategies) and metalinguistic awareness (i.e., awareness of metalanguage and language rules) of Years Ten and Eleven Sydney high school writers across three groups: Chinese-English biliterates, Chinese-English bilinguals, and English monolinguals. It also examines the relationship between the three groups’ levels of metacognition and text quality in English, and the relationship between the biliterates’ levels of metacognition and text quality in Chinese. Findings indicate biliterates are advantaged in error classification and rule explanation within metalinguistic awareness, while monolinguals are advantaged in their metacognitive knowledge about writing strategies. Socio-cultural contexts of the three groups such as past schooling, may have played a role in determining the kinds of metacognitive advantages they developed.
Doing the Corporate Business with Piercing the Corporate Veil Doctrine: Indonesia, Us And Uk Perspective
Authors: Kusuma Ng Catharina Enggar , Amboro Fl. Yudhi Priyo
Published: August 2020

The absence of piercing the corporate veil doctrine in the Indonesian company law shows that the subsidiaries of such corporate groups are considered a separate legal personality, hence it is probably almost impossible to held the parent company liable for its subsidiaries’ legal actions under any conditions. This research adopted a normative legal research with a comparative law study method. The goal of this research is describe the implementation of piercing the corporate veil doctrine in Indonesia, US and UK, then to make the points of contribution of this doctrine to be regulated properly in Indonesia. In fact, piercing the corporate veil doctrine is implemented in Indonesia, although there was not any normative legal basis of the doctrine itself, whereas in US and UK, the doctrine is implemented and further developed through precedents. Therefore, since there is an evident relationship between a parent company and its subsidiary, whereby in certain cases the parent company can and should be held liable for the acts of its subsidiary, there should be a more explicit regulation regarding both corporate groups and piercing the corporate veil doctrine.
Corruption: Working Hasn’t Completed
Authors: Swardhana Gde Made , Sukandia I Nyoman
Published: August 2020

This article discusses problems of corruption which until now hasn’t been completed in its eradication process. Every effort is made to find both internal and external causes in order to get the solution. The problem that is studied sociologically is, why is corruption incomplete? If corruption isn’t yet complete, and work isn’t finished yet, then how can work be completed? Understanding Corruption can be called work is complete, must be understood from the anti-corruption values and principles contained therein. It’s include honesty, independence, discipline, responsibility, hard work, simple, courage, and justice. It’s need to be applied by each individual to be able to overcome external factors so that corruption doesn’t occur. To prevent the occurrence of external factors, in addition to having it, each individual needs to deeply understand the anti-corruption principles of accountability, transparency, fairness, policy, and policy control. Therefore the relationship between anti-corruption principles and values is an inseparable unity. Success or failure to solve the problem of corruption is expected in the legal system that makes the handle in solving corruption cases, namely strengthening the legal structure, legal substance and legal culture of the community.
Generation and characterization of a novel mouse model that allows spatiotemporal quantification of pancreatic β-cell proliferation
Authors: Admin Ada , Tokumoto Shinsuke , Yabe Daisuke , Tatsuoka Hisato , Usui Ryota , Fauzi Muhammad , Botagarova Ainur , Goto Hisanori , Herrera Pedro Luis , Ogura Masahito , Inagaki Nobuya
Published: August 2020

Pancreatic β-cell proliferation has been gaining much
attention as a therapeutic target for prevention and treatment of diabetes. In
order to evaluate potential β-cell mitogens, accurate and reliable methods for
detection and quantification of the β-cell proliferation rate are
indispensable. In this study, we developed a novel tool that specifically
labels replicating β
cells as mVenus+ cells by using RIP-Cre;R26Fucci2aR mice expressing the
fluorescent ubiquitination-based cell cycle indicator Fucci2a in β cells. In
response to β-cell proliferation stimuli such as insulin receptor antagonist
S961 and diet-induced obesity (DIO), the number of EdU+ insulin+
cells per insulin+ cells and the number of mVenus+ cells
per mCherry+ mVenus- cells + mCherry-
mVenus+ cells were similarly
increased in these mice. Three-dimensional imaging of optically cleared
pancreas tissue from these mice enabled quantification of replicating β cells in
the islets and morphometric analysis of the islets following known mitogenic interventions
such as S961, DIO, pregnancy and partial pancreatectomy. Thus, this novel mouse
line is a powerful tool for spatiotemporal analysis and quantification of
β-cell proliferation in response to mitogenic
stimulation.
Validación de entrevistas por juicio de expertos en el estudio de la inclusión educativa en el área de lenguas extranjeras
Authors: De la Cruz Villegas Veronika , Gordillo Fuentes Eduardo Jesús
Published: August 2020

El objetivo de este artículo es mostrar las experiencias en torno a la conceptualización, validación e implementación de entrevistas elaboradas para analizar las prácticas educativas que convergen en la enseñanza y el aprendizaje de lenguas extranjeras a estudiantes con discapacidad visual en una universidad pública mexicana. Como estrategia de investigación, se diseñaron, validaron (a través del método de consulta a expertos) y aplicaron tres entrevistas para recuperar información sobre las prácticas educativas de carácter institucional, educativo y social que han impactado en los procesos de enseñar y aprender una lengua extranjera en estudiantes con discapacidad visual en el nivel superior. El diseño metodológico consistió de cinco pasos: 1) la elaboración del instrumento, 2) la implementación de este, 3) la consulta a expertos, 4) la reelaboración del instrumento y 5) el consenso de los expertos. Los hallazgos muestran que el uso del proceso de validación en cinco pasos secuenciales garantiza, a través del registro de las valoraciones de los jueces, antes y después del pilotaje del instrumento, la organización clara y coherente de la información en ítems de acuerdo con cada dimensión. El análisis de los datos obtenidos durante el proceso de validación arrojó un alto consenso por parte de los expertos, con una alta coherencia interna (alfa de Cronbach > 0.80) en cada una de las secciones de los instrumentos.
Sistem Kendali Rumah Pintar Menggunakan Voice Recognition Module V3 Berbasis Mikrokontroler dan IOT
Authors: Rahayu Anita , Hendri Hendri
Published: August 2020

Dalam beberapa tahun terakhir, teknologi membuat segalanya lebih mudah dilakukan.Salah satunyaadalah sistem otomatisasi pada rumah pintar. Pemaparan dari hasil tugas akhir yang bertujuan untuk merancang sistem otomatis rumah pintar menggunakan Arduino UNO sebagai pusat pengontrolan, Voice Recognition sebagai pengolah suara, ESP8266 sebagai penghubung ke jaringan Wi-Fi, modul relay sebagai saklar elektronik dan catu daya sebagai sumber. Pada tugas akhir ini, penulis menggunakan metode penelitian kuantitatif. Dimana pengujian dilakukan menggunakan data berupa angka untuk menganalisis keterangan yang ingin diketahui sehingga terlihat lebih detail dan jelas. Untuk memudahkan pembacaan, penulis menggunakan tabel-tabel sebagai penjabaran hasil pengujian.Setelah pengujian, hasil dari tugas akhir ini menunjukkan rancangan dapat mengontrol alat elektronik di rumah menggunakan perintah suara dan perintah jarak jauh dengan aplikasi Telegram di Android. Data yang diambil menunjukkan bahwa fungsi keseluruhan cukup baik dan membutuhkan jeda sekitar 2 detik dari saat perintah diberikanhingga respon pengaktifan outputbekerja.Persentase rata-rata suara yang diterima dari suara yang diucapkan dalam pengujian adalah 80.2%.
Monitoring Turbin Angin Menggunakan Smartphone Android
Authors: Pratama Randy Yonanda , Yuhendri Muldi
Published: August 2020

Wind turbines function as producers of mechanical power to drive generators in wind power plants. One factor that needs to be considered in the operation of wind turbines is the maximum capacity of the generator. Wind turbines must operate below the generator rating so as not to cause damage to the generator. Therefore, the operation of the wind turbine needs to be monitored and controlled to keep it operating within the generator rating limits. In this paper a horizontal axis wind turbine monitoring sistem is proposed using an Android smartphone. Wind turbine monitoring includes wind speed and turbine rotation speed parameters. This parameter data is obtained from sensors that are processed with Arduino Mega 2560. Data from Arduino is sent via the Bluetooth HC-04 module to be displayed on an Android smartphone. The experimental results show that the proposed wind turbine monitoring system has worked well. This can be seen from the wind speed and turbine rotation data that is displayed on android is exactly the same as the data on the measuring instrument
Sistem Monitoring dan Kontrol Motor AC 3 Phasa Melalui Inverter dengan Protokol Modbus Menggunakan Visual Basic Berbasis Atmega 2560
Authors: Kartika Emillia , Ta'ali Ta'ali , Hastuti Hastuti
Published: August 2020

A three-phase induction motor is one of the electric machines and is classified as an AC motor that is widely used in the industrial world. The development of control systems in the industry will not be separated from the data communication system. To send data from the field (sensor) to the controller, for communication between controllers, to send data from the controller to the computer, all require data communication. One of the most widely used data communication systems in industrial control systems is the Modbus protocol. Even in the world of education there are also many studies that develop control systems using modbus communication. The speed regulation of three phase induction motor can be done in various ways one of them is by using Variable Speed Drive which functions to adjust the frequency of the source so as to get the desired motor speed (rpm). Communication between VSD, Arduino and PC with the MODBUS protocol is a system built to be able to monitor the performance of a three phase induction motor.
BEING AT HOME IN SOLITARY QUARANTINE. PHENOMENOLOGICAL ANALYTICS AND EXISTENTIAL MEDITATIONS
Authors: EL-BIZRI Nader
Published: August 2020

This ontological investigation is mediated via multifaceted phenomenological analytics and existential mediations over the architectural mode of being at home in solitary quarantine under communal global lockdowns. The present line of inquiry is undertaken by way of probing the attuned metamorphoses in solitude of the lived experiencing of the intertwined phenomena of space-time, embodiment-in-the-flesh versus being-with-others via cybernetic and telecommunication technologies, dwelling amidst things and paraphernalia, and the underlying affectivities of the mode of being-toward-death.
Entre el distanciamiento y la conectividad
Authors: Martin María Victoria , Kap Miriam , Génova Elena
Published: August 2020

El distanciamiento social obligatorio impuesto por el avance del COVID-19 condujo a poner en cuestión la normalidad y repercutió inmediatamente en las aulas. La suspensión de clases presenciales presentó un gran desafío, y fueron los/as docentes quienes rápidamente buscaron alternativas para garantizar la continuidad pedagógica y vincularse con sus estudiantes. Las experiencias de enseñanza y de aprendizaje mutaron y generaron nuevas formas de apropiación, de producción y de consumo dentro de la compleja ecología de medios. Experiencias didácticas transformadoras se fueron presentando en contextos diversos en ambientes con y sin disposición tecnológica.
Juventudes y comunicación política
Authors: Secul Giusti Cristian
Published: August 2020

El artículo recupera un trabajo realizado en contexto pandémico y en el marco de las clases de la asignatura Estudios sobre Política y Sociedad II de la Tecnicatura Superior en Comunicación Pública y Política de Facultad de Periodismo y Comunicación Social (UNLP), donde se abordaron los pensamientos políticos de Simone de Beauvoir y Hannah Arendt presentes en «Idealismo moral y realismo político» (1948) y «¿Qué es la política?» (1950). Dicho acercamiento permitió analizar planteos existencialistas y de transformación en pos de una reivindicación de la política y de la pluralidad como concepción fundamental para atravesar dificultades y complejidades sociales.
Rules for technical operation of thermal power installations and regulatory technical framework for heat supply
Authors: Muzyka R. R.
Published: August 2020

«Правила технической эксплуатации тепловых энергоустановок» (далее ПТЭ ТЭУ) устанавливают требования по технической эксплуатации котельных различных типов, тепловых сетей и сооружений на тепловых сетях, систем теплопотребления всех назначений (за исключением тепловых энергоустановок тепловых электростанций и транспортных средств), т. е. касаются широкого круга производителей, поставщиков и потребителей тепловой энергии. Действующие в настоящее время ПТЭ ТЭУ утверждены и введены в действие в 2003 году.
On critical expansion ratio of natural gas in turboexpanders
Authors: Kosyuk A. V.
Published: August 2020

В последние годы в российской энергетике среди ученых различных университетов и организаций возник интерес к использованию детандер-генераторных агрегатов (ДГА), или просто турбодетандеров, на тепловых электростанциях.
DETERMINE REGIONAL STRATEGY IN IMPROVING THE COMPETITIVENESS OF AGRICULTURAL COMMODITIES IN GLOBAL MARKETS
Authors: Rum Irlan Adiyatma , Rijoly Jacobus Cliff Diky
Published: August 2020

Trade liberalization has affected Indonesian economy. The country success in international trade is truly determined by the regional sectoral competitiveness. The government recognized that agricultural commodities have higher degree of vulnerability to global trade pressures due to weak competitiveness. This study tried to identify the regional strategies that could be taken by the government in improving the competitiveness of agricultural commodity and determine the optimal solution that need to be considered. To determine the position of agricultural competitiveness, calculated Revealed Comparative Advantage (RCA), Revealed Comparative Trade Advantage (RCTA), and Trade Specialization Index (TSI) for some strategic commodities in agricultural Indonesia to export destinations. The results show that Indonesia experienced a decline in their competitiveness in global trade. It has been proved from the comparation over time and with other export countries. This study proposes regional strategy to improve national competitiveness based on their regional competitiveness.
Peningkatan Akurasi pada Prediksi Kepribadian Mbti Pengguna Twitter Menggunakan Augmentasi Data
Authors: Harahap Rizki Nurhaliza , Muslim Kemas
Published: August 2020

Kepribadian suatu individu perlu diketahui untuk membantu seseorang dalam mempertimbangkan beberapa hal, salah satunya perekrutan karier. Pada umumnya, kepribadian dapat diketahui melalui metode wawancara, observasi, maupun survei kuesioner. Akan tetapi, metode konvensional tersebut dinilai kurang praktis dari segi waktu dan materi karena dibutuhkan waktu yang lama dan biaya yang cukup besar untuk mengolah data. Selain itu, penggunaan metode konvensional juga dapat menimbulkan bias karena melibatkan orang ketiga dalam pengolahan data. Penelitian ini mencoba memberikan solusi dengan membangun model yang dapat melakukan prediksi terhadap kepribadian seseorang berdasarkan analisis data dan informasi dari media sosial Twitter. Data dan informasi tersebut akan diproses sehingga didapatkan prediksi kepribadian orang tersebut. Teori klasifikasi kepribadian yang digunakan adalah teori Myers-Briggs Type Indicator (MBTI). Penelitian ini juga mencoba menerapkan teknik augmentasi data untuk meningkatkan performa dari text mining task yang memiliki dataset sedikit. Hasil terbaik didapatkan dengan metode Random Forest menggunakan pembobotan Term Frequency-Inverse Document Frequency (TF-IDF) dan fitur yang tersedia pada Twitter. Penggunaan teknik augmentasi dapat meningkatkan akurasi hingga 30% dari akurasi awal sehingga hasil penelitian menunjukkan bahwa penggunaan teknik augmentasi data dapat meningkatkan performa pada model prediksi kepribadian MBTI.

Abstract

The personality of an individual needs to be known to help people in considering things, one of them is career recruitment. In general, personality can be known through interviews, observations, and questionnaire surveys. However, the conventional method is judged to be impractical in terms of time and material because it takes a long time and has considerable costs to process data. After all, the use of conventional methods can also cause bias because it involves a third person in data processing. The research tries to provide a solution by building a system that can predict the personality of a person based on the analysis of data and information from social media Twitter. The data and information will be processed so that the personality prediction is obtained. The personality classification theory used is the Myers-Briggs Type Indicator (MBTI) theory. The research also tries to implement data augmentation techniques to improve the performance of text mining tasks that have a slight dataset. The best results are obtained by the Random Forest method using the Term Frequency-Inverse Document Frequency (TF-IDF) weighted and the features available on Twitter. The use of augmentation techniques can increase accuracy by up to 30% from initial accuracy. So, the use of data augmentation techniques can be used to improve the performance of MBTI personality prediction models.
DAFTAR ISI
Authors: Daftar Isi
Published: August 2020

Daftar Isi
Nitrate Reductase Nanoparticles: Synthesis and Characterization
Authors: Shelly  , Minakshi Sharma
Published: August 2020

Nanoparticles of enzyme Nitrate reductase (NaR) a soluble homodimer enzyme of ∼100 kDa polypeptide with cofactors – FAD, heme-molybdopterin (Mo-MPT) and electron donor NAD(P)H, catalyses the reduction of nitrate to nitrite has been synthesised. Nanoparticles of Nitrate reductase enzyme have been prepared by chemical desolvation method including glutaraldehyde cross-linking to form the nanoaggregate. Characterisation of NaR nanoparticles has been made by Transmission Electron Microscopy (TEM), UV-Visible Spectroscopy and by electrochemical Impedance Spectroscopic Study (EIS). TEM study revealed the size of globular aggregated was in the range of 20–30 nm. UV Visible spectroscopic studies depicted that the absorption of NaR NPS is much higher at 560 nm than that of the free enzyme, which showed maximum absorption at 540 nm. NaR NPs aggregates formed were more active, highly stable, have a higher shelf life and can be reused repeatedly. Enzyme nanoparticles with 10-100 nm dimensions and exhibit unique physical, chemical and catalytic properties due to increased surface area. Nitrate reductase nanoparticles can be used as a biochemical tool to increase protein production and grain yield by promoting amino acids production in plants. The synthesised NaR NPs are used in the fabrication of enzyme-based nanosensor in the detection of nitrates in drinking water and serum samples.
Phytochemical evaluation, HPTLC analysis and in-vitro antioxidant activity of hydroalcoholic leaf extract of Grewia hirsuta collected from Western Ghats forest
Authors: Dattatraya Kature  , Gaurav Gupta  , Ritu Gilotra
Published: August 2020

In-vitro antioxidant action of hydroalcoholic leaf extract of Grewia hirsuta (HAEGH) has been examined using one, “1-diphenyl-2-picryl-hydrazil (DPPH) free from radical scavenging” actions. The plant collected from the forest of the Western Ghats region of Karnataka province. The motive for plant collection from a specific location is the plant of forests exhibits the variation in growth, quantity, and quality of their active ingredients and secondary metabolites due to influence ecological factors like effect changes in location, soil, climate, etc. The work corresponds to preliminary phytochemical investigation for diverse phytoconstituents and quantitative phytochemical analysis of total phenolic, flavonoids & alkaloids content (TPC, TFC & TAC respectively) was evaluated with advanced methods. “HPTLC (High performance thin-layer” chromatography) fingerprint investigation was achieved for qualitative determination of the likely number of elements present in the hydroalcoholic extract. In-vitro antioxidant activity of HAEGH has been determined through hydroxyl radical scavenging assay that exhibited strong dose-dependent antioxidant activity as compared with standards compound, ascorbic acid. The IC50 value of HAEGH found, 25.90 % inhibition and for ascorbic acid, it was 17.68%. The Preliminary phytochemical estimation found presence of flavonoids, alkaloids, glycosides, phenol, proteins, diterpins and quantitative phytochemical analysis estimation of TPC, TFC & TAC found to be 3.627%, 4.059% & 5.671% respectively. HPTLC analysis of HAEGH at 354nm reveals the presence of a compound with Rf value 0.44 compare with Rf value 0.46 of quercetin. These outcomes indicated that the hydroalcoholic leaf extract of Grewia hirsuta plant contains phytoconstituents that exhibit antioxidant activity possible because of the existence of bioactive compounds.
Physico-chemical characteristics, antibacterial, and antioxidant activities of genuine forest honey from East Kalimantan
Authors: Prayitno Y.A. , Emmawati A. , Rahmadi A.
Published: August 2020

In the dense tropical forests of Kalimantan, Apis dorsata produces forest honey with
pollen diversity that has the potential to have unique antibacterial and antioxidant
properties. This study is aimed to report the physicochemical characteristics, antioxidant
activity and antibacterial analysis of forest honey from East Kalimantan. A total of nine
samples of forest honey were purchased from local buyers of several regions. The power
of hydrogen (pH), water content, diastase enzymes, fructose levels, and glucose levels
were measured. Antioxidant activity was measured with ABTS assay. Antibacterial
activity was conducted against Staphylococcus aureus, Bacillus cereus, Escherichia coli,
and S. enterica serovar Typhi. Fourier Transform Infra-Red (FTIR) identified antibacterial
functional groups. Honey samples from tropical forests in East Kalimantan had pH
between 2.93±0.06 and 3.83±0.06, a moisture content between 18.44±0.64 and
25.67±0.29%, fructose levels between 7.85±0.05 and 17.73±0.13%, and glucose levels
between 1.24±0.16 and 17.34±0.14%. Goa Tembenus honey showed the highest IC50
antioxidant activity and the highest Diastase Enzyme activity. Goa Tembenus and Bongan
honey showed good antibacterial activity against Gram-positive and Gram-negative.
Minimum inhibitory levels of honey were found at concentrations of 25% and 30%.
Honey from tropical forests in East Kalimantan has H2O2 as an antibacterial component.
Students are almost as effective as professors in university teaching
Authors: Feld Jan , Salamanca Nicolás , Zölitz Ulf
Published: August 2020

No description supplied
Analisis Perbandingan Biaya pada Pekerjaan Pengerukan di Alur Pelabuhan Bandar Bakau Jaya Banten
Authors: Firdaus Aden , Rizkiansyah Muhammad , Nirwana Yessi
Published: August 2020

ABSTRAKPelabuhan Bandar Bakau Jaya yang terletak di Provinsi Banten saat ini dapat melayani kapal yang berjenis 5.000 DWT, dan rencananya akan melayani kapal 10.000 DWT. Pekerjaan pengerukan akan dilakukan pada Alur Pelabuhan dengan dimensi panjang 2.391 m dengan jenis tanah adalah tanah halus berpasir. Tujuan dari penelitian ini adalah membandingkan biaya dan waktu pelaksanaan dari masing- masing jenis kapal keruk yang dapat melakukan pekerjaan pengerukan dengan kondisi tanah yang ada di alur pelabuhan. Metode yang digunakan adalah dengan memperhitungkan berapa lama waktu pekerjaan pengerukan sehingga didapatkan biaya dari masing-masing jenis kapal keruk. Hasil dari analisis didapatkan 3 jenis kapal keruk yaitu, TSHD dalam waktu 2,11 bulan dan biaya Rp27.316.912.819,63, SD dalam waktu 8,34 bulan dan biaya Rp27.887.202.652,35, dan CSD dalam waktu 6,08 bulan dan biaya Rp37.995.671.214,00. Jenis kapal keruk yang paling efisien untuk pekerjaan pengerukan di alur pelabuhan ini adalah TSHD dengan 7 tugboat dan barge.Kata kunci: pengerukan, alur pelayaran, kapal keruk ABSTRACTBandar Bakau Jaya Port, located in Banten Province, currently serves 5,000 DWT vessels, and it is planned to serve 10,000 DWT vessels. Dredging work will be carried out on the Port Channel with a dimension of 2,391 m in length with a fine sandy soil type. The purpose of this study is to compare the cost and implementation time of each type of dredger that can carry out dredging work with existing soil conditions in the port channel. The method used is to calculate how long the dredging work is so that the cost of each type of dredger is obtained. The results of the analysis found 3 types of dredges namely, TSHD in 2.11 months and costs Rp27,316,912,819.63, SD in 8.34 months and costs Rp27,887,202,652.35, and CSD in 6, 08 months and costs Rp37,995,671,214.00. The most efficient type of dredger for this work is TSHD with 7 tugboats and barges.Keywords: dredging, fairway, dredger
Evaluasi Keandalan Jembatan Gantung Pejalan Kaki Dengan Variasi Letak dan Jenis Beban Lalu Lintas
Authors: Widyaningsih Euneke
Published: August 2020

ABSTRAKUntuk mendukung pembangunan infrastruktur jembatan, pemerintah mengeluarkan panduan untuk perencanaan jembatan gantung dengan judul Surat Edaran Menteri Pekerjaan Umum No. 02/SE/M/2010 tentang Pemberlakukan Pedoman Perencanaan dan Pelaksanaan Konstruksi Jembatan Gantung Untuk Pejalan Kaki. Jembatan gantung yang dirancang sesuai dengan panduan tersebut harus mampu menahan beban pejalan kaki sebesar 5 kPa. Dengan mengacu pada pedoman tersebut, direncanakanlah sebuah jembatan gantung dengan panjang total 127.34 meter. Agar dapat mengetahui perilaku jembatan terhadap beban yang direncanakan, dibuatlah pemodelan jembatan menggunakan software MidasCIVIL dengan menggunakan 4 variasi letak pembebanan dan 80 variasi beban mewakili bobot pejalan kaki dan kendaraan bermotor roda dua. Tujuan dilakukannya analisis ini adalah untuk mengetahui nilai keandalan struktur yang direncanakan dengan beban sesuai Surat Edaran Menteri Pekerjaan Umum No. 02/SE/M/2010 terhadap variasi beban pejalan kaki dan kendaraan bermotor yang sesungguhnya mungkin terjadi pada jembatan. Evaluasi struktur menggunakan metode probability based menghasilkan keandalan struktur jembatan sebesar 100% yang dianalisis terhadap lendutan, tegangan kabel, tegangan batang penggantung serta tegangan pilar. Sehingga dapat dikatakan bahwa beban 5 kPa yang disyaratkan oleh pedoman memiliki nilai yang konservatif dan akan menghasilkan struktur jembatan yang sangat aman.Kata kunci: : Jembatan Gantung, Variasi Letak Beban, Pejalan Kaki, Probability Based Design ABSTRACTTo support the establishment of bridge infrastructure, the government issued a guide for planning a suspension bridge with the title Surat Edaran Menteri Pekerjaan Umum No. 02 / SE / M / 2010 concerning the Implementation of Guidelines for Planning and Construction of Suspension Bridges for Pedestrians. Suspension bridges designed according to these guidelines must be able to withstand pedestrian loads of 5 kPa. With reference to these guidelines, a suspension bridge is planned with a total length of 127.34 meters. In order to know the bridge's behavior towards the planned load, a bridge modeling was made using MidasCIVIL using 4 position of loading and 80 load variations representing pedestrian weight and two-wheeled motorized vehicles. The purpose of this analysis is to determine the value of the bridge reliability that planned with load according to the Surat Edaran Menteri Pekerjaan Umum No. 02 / SE / M / 2010 against variations in pedestrian and motor vehicle loads that might actually occur on bridges. Structural evaluation using probability-based methods produces 100% bridge structure reliability which is analyzed for deflection, cable stress, hanger stress and pillar stress. So, it can be said that the 5 kPa load required by the guidelines has a conservative value and will produce a very safe bridge structure.Keywords: Suspension Bridge, Load Position Variation, Pedestrian, Probability Based Design