bluuebunny/crossref_metadata_2025 huggingface dataset:
Enantioselective synthesis of anhydrogukulenin A C2-acetate
Authors: Combs Josh , Wright Timothy , Chen Lei , Holmes Ryan , Qin Bo , Oh Joonseok , Crawford Jason , Herzon Seth
Published: August 2023

We report an enantioselective synthesis of anhydrogukulenin A C2-acetate (31), a potential precursor to the antiproliferative bis(tropolone) metabolites known as the gukulenins. Key steps in the synthetic sequence include a directed C–H arylation of an exo-2-norbornyl picolinamide using a hindered, electron-rich arene coupling partner, a tandem Grob fragmentation–diastereoselective α-methylation to establish the highly-substituted cyclopentane rings of the target, a novel one-carbon ring expansion of an α-iodo-ortho-benzoquinone monoketal, a two-fold Stille coupling using the novel linchpin reagent (E)-1,2-di(tributylstannyl)-1-ethoxyethylene (15), and late-stage, diastereoselective addition of an α-tropolone to an α-acetoxy aldehyde, which may mirror the biosynthesis of the metabolite. We present the first evidence supporting the formation of carbinolamides (–)-gukulenins C (3) and D (4) from the parent metabolite (–)-gukulenin A (1) by the addition of ammonia to the α-acetoxy aldehyde. This work provides a platform to elucidate the structure–function relationships and mechanism of action of the gukulenins, and, with further development, may provide access to the targets themselves.
Direct Decarboxylation of Trifluoroacetates Enabled by Iron Photocatalysis
Authors: Fernandez-Garcia Sara , Chantzakou Veronika O. , Julia-Hernandez Francisco
Published: August 2023

Trifluoroacetates are the most abundant and accessible sources of trifluoromethyl groups, which are key components in pharmaceuticals and agrochemicals. The generation of trifluoromethyl reactive radicals from trifluoroacetates requires their decarboxylation, which is hampered by their high oxidation potential. This constitutes a major challenge for redox-based methods, because of the need to pair the redox potentials with trifluoroacetate. Here we report a strategy based on iron photocatalysis to promote the direct photodecarboxylation of trifluoroacetates that displays reactivity features that escape from redox limitations. Our synthetic design has enabled the use of trifluoroacetates for the trifluoromethylation of more easily oxidizable organic substrates, offering new opportunities for late-stage derivatization campaigns using chemical feedstocks, Earth-abundant catalysts, and visible-light.
Navigating the Potential Energy Surface of CdSe Magic-Sized Clusters: Synthesis and Interconversion of Atomically Precise Nanocrystal Polymorphs
Authors: Ripberger Hunter , Schnitzenbaumer Kyle , Nguyen Lily , Ladd Dylan , Levine Kelsey , Dayton Damara , Toney Michael , Cossairt Brandi
Published: August 2023

Magic-sized clusters (MSCs) are kinetically stable, atomically precise intermediates along the quantum dot (QD) reaction potential energy surface. Literature precedent establishes two classes of cadmium selenide MSCs with QD-like inorganic cores: one class is proposed to be cation-rich with a zincblende crystal structure, while the other is proposed to be stoichiometric with a “wurtzite-like” core. However, the wide range of synthetic protocols used to access MSCs has made direct comparison of their structure and surface chemistry difficult. Furthermore, the physical and chemical relationship between MSC polymorphs has yet to be established. Here, we demonstrate that both cation-rich and stoichiometric CdSe MSCs can be synthesized from identical reagents and can be interconverted through the addition of either excess cadmium or selenium precursor. The structural and compositional differences between these two polymorphs can be contrasted using a combination of 1H-NMR spectroscopy, x-ray diffraction, pair distribution function (PDF) analysis, inductively coupled plasma optical emission spectroscopy, and UV-vis transient absorption spectroscopy. The subsequent polymorph interconversion reactions are monitored by UV-vis spectroscopy, with evidence for an altered cluster atomic structure observed by powder x-ray diffraction and PDF analysis. This work helps simplify the complex picture of the CdSe nanocrystal landscape and provides a method to explore structure-property relationships in colloidal semiconductors through atomically precise synthesis.
Nuclear Quantum Effects in Gas-Phase 2-Fluoroethanol
Authors: Arandhara Mrinal , Ramesh Sai G.
Published: August 2023

Torsional motions along the FCCO and HOCC dihedrals lead to the five unique conformations of 2-fluoroethanol. In this work, we explore how nuclear quantum effects (NQEs) are manifest in the intramolecular landscape along these two dihedrals, through the use of path integral simulations. We have first developed a full dimensional potential energy surface using the reaction surface Hamiltonian framework. On this potential, we have carried out path integral molecular dynamics at several temperatures starting from the minimum energy well to explore structural influences of NQEs. With umbrella sampling and metadynamics simulations at 300 K and 50 K, we have explored whether NQEs have effects on the free energy landscape. Significant influences are found near the cis region of the dihedrals, which can be understood through the trends in the radii of gyration of the atomic ring polymers. We have also computed the infrared spectra at 300 K and 50 K with thermostatted ring polymer molecular dynamics simulations, which agrees well with experimental band positions.
Silver-Based Supramolecular Hydrogel for the Development of Smartphone-Enabled Alkaline Phosphatase Sensor
Authors: Chaudhury Smarak Islam , Das Sourav , Bhatt Preeti , Sen Bhaskar , Rana Subinoy
Published: August 2023

Alkaline phosphatase (ALP) is an important protein responsible for various conditions related to hepatobiliary, osteopenia, pregnancy, and certain cancers. Developing an easy-to-use paper-based sensor for ALP would provide a point-of-care diagnostic device. A silver-coordinated cytidine hydrogel is a potential candidate to show responses under different concentrations of ALP. Herein, we prepared and characterized a three-component hydrogel system comprising cytidine, boric acid, and silver nitrate. The gelation occurs rapidly within a minute at room temperature and atmospheric pressure, which makes the system more convenient to use. Reduction of Ag+ by the in situ generated ascorbic acid by ALP allows the development of colorimetric sensor based on the gel-coated paper, enabling quantification of ALP concentration. This portable sensor works efficiently on a smartphone color-scanning app, making point-of-care detection easier. RGB values obtained from scanning indicate the ALP concentration in the range of 1-100 nM, which is independent of mobile cameras. The hydrogel exhibits excellent solvo-reversibility and enables naked-eye colorimetric detection of ALP with a detection limit of 0.23 nM (0.016 U/L). The sensing strategy works well in spiked human serum with a detection limit of 0.34 nM (0.023 U/L) in solution and paper-based sensors. Overall, the cytidine-based gel system presents an effective point-of-care diagnostic system for detecting ALP with high sensitivity.
Cold-bonded biochar-rich lightweight aggregates for net-zero concrete
Authors: Wyrzykowski Mateusz , Toropovs Nikolajs , Winnefeld Frank , Lura Pietro
Published: August 2023

An emerging strategy to remove CO2 from the atmosphere and compensate for the greenhouse-gas emissions of cement and concrete is based on incorporating biochar into concrete. With this approach, concrete can be turned into a functional carbon sink (C-sink). Until now, biochar has been used without modification to replace part of the cement or of the aggregates in concrete. However, this technology comes with a number of practical problems, which include the high water absorption of the biochar (due to its high specific surface) and hazards (dust, risk of combustion). In this paper we present an alternative approach in which biochar is first processed into lightweight aggregates in a cold-bonding process. To this end, biochar is pelletized together with a small amount of hydraulic binder and with water and forms round pellets that further harden with hydration time. In this way, carbon-rich lightweight aggregates (C-LWA) are obtained that are easier to handle than the pure biochar. The C-LWA pellets have similar porosity and strength as conventional LWA and can be used for similar applications. Yet, the CO2 emissions from sintering traditional LWA are avoided and the C-LWA are instead an effective C-sink. We demonstrate that it is possible to incorporate in the pellets and eventually in the concrete a sufficient amount of carbon to compensate for the original emissions of concrete. The net-zero emissions concrete obtained with this approach possesses mechanical performance sufficient for typical structural applications in buildings.
Adsorption of Phenol using Cellulose and Hydrochar: Kinetic, Isotherm, and Regeneration Studies
Authors: Wibiyan Sahrul , Wijaya Alfan , Siregar Patimah Mega Syah Bahar Nur
Published: August 2023

In this study, hydrocarbons were obtained through the hydrothermal carbonization synthesis method. The XRD data of the cellulose sample revealed 2θ angles of 15.46°, 22.34°, and 34.36°, indicating that the cellulose sample under investigation had an amorphous structure. The XRD data of the hydrocarbon sample showed a 2θ angle of 25.72°, indicating the presence of graphitic carbon. The FTIR spectra of both cellulose and hydrocarbon exhibited similarities at wave numbers 3394 cm-1, 2893 cm-1, 1662 cm-1, 1000-1200 cm-1, and 847 cm-1. BET analysis revealed that the hydrocarbon material surface area measured was 7.366 m²/g, measured pore volume for the entire sample was 0.008 cc/g, and the average size of the pores was 3.189 nm. The optimal pH variation for cellulose was at pH 10, with an adsorption capacity of 10.75 mg/g, on the other hand, was tested at pH 6 and demonstrated an adsorption capacity of 12.74 mg/g. The adsorption kinetics model for both adsorbents was PSO, and the adsorption isotherm model was Freundlich. Cellulose exhibited a maximum adsorption capacity of 35.336 mg/g, while hydrochar demonstrated a maximum adsorption capacity of 21.008 mg/g. It is noteworthy that both adsorbents were capable of being reused for up to five cycles.
"Colonisation ... in top gear": New Zealand Architecture in the 1870s
Authors: McCarthy Christine
Published: August 2023

The decade opened with the departure of British imperial troops from our shores, in anticipation of the end of the New Zealand Wars. This coincided with Julius Vogel's bold plans for New Zealand public infrastructure supporting roads, railways and immigration, requiring overseas borrowing of £10 million. Part of Vogel's motivation included the idea that employment for Māori would create peace between Māori and Pākehā.
A Scotsman abroad: the architecture of John Scotland in colonial Nelson
Authors: Addison Paul A.
Published: August 2023

John Scotland was one of a small number of architects practising in Nelson during the 1870s. Born in Stirlingshire in 1812, he was the son of a master mason and followed that same calling. However, only scant details of his life are known until he emigrated to New Zealand aged in his mid-50s. As with a number of his contemporaries in the building trades, Scotland turned to architecture, and established a practice in Nelson in 1866. He designed some of that city's grandest homes, including Melrose and Fellworth, both now listed by Heritage New Zealand, as well as various commercial premises and a synagogue. Scotland returned to his native land in 1885, and died in Glasgow two years later.
200 Architects in the 1870s? Is that figure real?
Authors: Humphris Adrian , Mew Geoff
Published: August 2023

In this paper we are using our architects dataset to identify every person who called themself an architect in New Zealand in the 1870s. An initial check of our database produced around 200 names, but we know from our previous studies that this figure needs to be refined to gauge the importance of their work, or even determine whether some of them could be truly called architects.We have taken our data and used key attributes to try to quantify and qualify our architects. For example, one initial crude sort was based on the numbers of buildings designed over their total careers; this should give some indication of their presumed competence and possible success in the profession. So-called architects who designed zero structures were assigned to the lowest class; other classes were; 1-5 structures; 6-20; and >21, the latter appearing to be the most successful. We also considered where each person was located for the bulk of the 1870s to see if there might be geographical trends related to their success or otherwise. To finish our analysis we have chosen a few architects as examples from each of our classes and described them in more detail to explain perceived trends.
La omnívora brevedad en Cartucho de Nellie Campobello
Authors: Malaver Ary
Published: August 2023

Los relatos en Cartucho: Relatos de la lucha en el Norte de México de Nellie Campobello destacan por un carácter narrativo innovador sustentado en una convergencia de estilos en su composición. Teniendo como punto de partida la marcada brevedad de varios de sus textos, este trabajo recurre a diversas formulaciones sobre el microrrelato y otras formas breves para explorar la incertidumbre que ha generado la experiencia lectora de Cartucho. El eclecticismo o condición omnívora de la obra se evidencia en los varios puntos de contacto entre los textos de Cartucho y formas como el epigrama, el epitafio, el corrido, la crónica, la viñeta, la fotografía, la prensa escrita y el cine. Esta naturaleza omnívora se propone a su vez como elemento contextualizador en relación con la incertidumbre genérica que se le ha atribuido a esta obra desde su aparición. Se examinan también distintas relaciones entre el estilo de los textos en Cartucho y la exposición de su autora a diversos procesos histórico-culturales en México durante las primeras décadas del siglo XX.
lo imposible palidece ante la improbabilidad de no morir cada día
Authors: Georas Santos Chloé Sophia
Published: August 2023

My poem is about the improbability of not dying every day.
Decolonizing American Spanish: Eurocentrism and Foreignness in the Imperial Ecosystem. By Jeffrey Herlihy-Mera. Pittsburgh, PA: University of Pittsburgh Press, 2022. 284 Pages.
Authors: Gómez Leila , Muñoz-Díaz Javier
Published: August 2023

review of book
Essential medicines for cats and dogs in russian veterinary practice
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Akchurin S.V. , Dyulger G.P. , Akchurina I.V. , Bychkov V.S. , Sedletskaya E.S.
Published: August 2023

In Russia, as in other countries around the world, the number of companion animals is increasing and the demand for veterinary services consequently. Increasing demand leads to the emergence of new services and goods, including medicines. The number of medicines used to treat small animals runs into the thousands. However, not all medicines are widely used in veterinary practice. The World Small Animal Veterinary Association (WSAVA), following the approach of the World Health Organisation, has introduced the practice of defining essential medicines to identify the most important medicines in veterinary medicine. This enables veterinarians to achieve an optimal level of expertise in the pharmacotherapy of the most common and important diseases of dogs and cats through self-education, and assists regulatory authorities in monitoring the supply of essential medicines to the veterinary industry, including the implementation of import substitution work, assist veterinary clinic managers in compiling a list of medicines that must be available, contribute to the quality of veterinary education, in particular by improving the quality of teaching the subject “Veterinary Pharmacology”. As part of the study, two lists of essential and complementary medicines for cats and dogs used in Russian veterinary practice were compiled with with the help of experts from the veterinary industry. The lists are divided into sections reflecting the main areas of veterinary pharmacotherapy.
Effect of the probiotic “Enzimsporin” on the morphophysiological parameters of the Lena sturgeon and beluga hybrid in aquaculture
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Pronina G.I. , Bubunets E.V. , Glebov A.P. , Zhelankin R.V.
Published: August 2023

The use of probiotics is recommended for sustainable growth, increased resistance and efficiency of feed assimilation. Currently, there are commercial probiotic products prepared from the bacteria Bacillus sp., Lactobacillus sp., Enterococcus sp., Carnobacterium sp. The use of the probiotic supplement “Enzimsporin” in fish farming is in its infancy. However, information is available on the effectiveness of its use in rainbow trout. In this regard, an urgent task is to study the effect of the probiotic “Enzimsporin” on the morphophysiological parameters of the juvenile hybrid of Lena sturgeon and beluga (Lenbel) under existing cultivation conditions. At the initial stage, the fish were divided into 8 groups of 50 fish each according to the principle of pairs of analogues. Large and small individuals were divided into four groups: control and experimental with a dose of Enzimsporin of 1 g/kg, 1.5 g /kg and 2 g/kg of feed, respectively. The duration of the experiment was 60 days. Total catches were made at the beginning and end of the experiment, and intermediate catches were made every 15 days, individually weighing 25–35% of the total number of fish in the pool. The physiological state and immune status of Lenbel were assessed by hematological and cytochemical parameters. Blood for analysis was collected from the caudal vein of fish in vivo. Leukocyte composition and the proportion of immature cell types were determined in Pappenheim-stained peripheral blood smears under a digital microscope. The phagocytic activity of fish neutrophils was evaluated by a lysosomal cation test using a cytochemical method with bromophenol blue. During the two months of the experiment, the main hydrochemical parameters (pH, nitrites, nitrates, ammonium), water temperature and the dissolved oxygen content were within the technological norms. The best absolute and relative growth rates were obtained in the experimental groups receiving a probiotic at a dose of 1.5 g/kg of feed. These fish had high indicators: absolute and relative growth, absolute and relative growth rate, mass accumulation coefficient. The best survival rate was recorded in the group of small yearlings of Lenbel at a probiotic dose of 2 g/kg of feed. In large fish, the maximum survival rate (80%) was recorded at a dose of 1 g/kg of “Enzimsporin”. There is significantly more lysosomal cationic protein in the blood neutrophils of the experimental groups – activation of cellular immunity.
Sainfoin (Onobrychis Adans .): a beneficial crop in organic grassland farming (review)
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Lazarev N.N. , Shitikova A.V. , Kurenkova E.M. , Kukharenkova O.V.
Published: August 2023

Perennial legumes are the most beneficial crops in the organic grassland farming. These crops include sainfoin, which should take its rightful place in forage lands, especially in modern conditions of increasing aridity. Three species are cultivated in Russia: Onobrychis viciifolia Scop., O. arenaria (Kit.) DC and O. transcaucasica Grossh. The cultivation of sainfoin is of great ecological importance due to its special ecological properties and chemical composition. It has a deep and highly branched root system, capable of absorbing nutrients from deep soil layers. The root system of sainfoin absorbs minerals from hard-to-reach soil compounds, so it is little responsive to fertilisation, and can be successfully used in organic grassland farming. Unlike other leguminous grasses, with the exception of the birdsfoot trefoil, sainfoin does not cause bloat in ruminants. This is due to the presence of condensed tannins (CTs) in the plant in the amount of 30–80 g per 1 kg of dry matter. СТs increase the amount of non-degradable protein in the rumen, which prevents bloat in ruminants, reduces methane emissions and nitrogen compounds in urine, which in turn reduces the impact of greenhouse gases on the heat balance of the Earth. СТs have shown in vivo anti-parasitic activity against helminths in sheep and goats, improving feed nutrient utilisation and increasing animal productivity. Sainfoin fixes atmospheric nitrogen in an amount up to 150 kg/ha and does not require the application of nitrogen fertilisers, which can pollute groundwater and atmospheric air. Enriching the soil with nitrogen and other nutrients due to their biological accumulation in the upper soil layer, sainfoin contributes to soil fertility. sainfoin provides yields from 4 to 7 t/ha of dry matter with a productive longevity of herbage for 4–7 years reducing the cost of reseeding.
Karbon ayak izi tespiti: Osmaniye Korkut Ata Üniversitesi örneği
Authors: YAVUZ Ali Burak , KARA Osman , YANIKTEPE Bülent
Published: August 2023

Dünya nüfusunun artması ve teknolojik gelişmelerin hızlanması ile günlük tüketim ihtiyaçlarımız değişiklik göstermeye başlamıştır. Özellikle fosil yakıt ve elektrik tüketimine doğru yönelim artmıştır. Artan enerji tüketimleri sonucunda dünyamızda küresel ısınma ve iklim değişikliği konuları bir tehdit haline gelmiştir. Bu kapsamda birçok hükümet sera gazı ile mücadele etmek ve zararlı etkilerini en aza indirmek için tedbirler almaya başlamıştır.

Bu çalışmada Osmaniye Korkut Ata Üniversitesi Karacaoğlan yerleşkesinin karbon ayak izi hesaplanmıştır. Hesaplamalar 14064-1 standardı ve Hükümetlerarası İklim Değişikliği Paneli (IPCC) Ulusal Sera Gazı Envanteri Yönergelerinden elde edilen emisyon faktörleri baz alınarak yapılmıştır. Hesaplamalarda 2019, 2020 ve 2021 yıllarındaki tüketim verileri kullanılmıştır. 2019 yılında kapsam-1 ve kapsam-2 emisyonları toplamı 2.995,70 ton CO2e, 2020 yılında 1.913,96 ton CO2e ve 2021 yılında ise 2.659,14 ton CO2e olarak hesaplanmıştır. COVID-19 tedbirleri sonucunda 2020 yılında uzaktan eğitime geçiş dönemiyle özellikle fosil yakıtlardan kaynaklı emisyon oranlarında önemli bir azalış olduğu tespit edilmiştir.
Transformation of the human resouces potential of the sphere of organization and management of the national economy in line with the synergy of security and economic progress
Authors:   Центр системных исследований, ЛАРИОНОВ И.К. , ГУРЕЕВА М.А. ,   Российский новый университет (РосНОУ)
Published: August 2023

В условиях кардинального изменения парадигмы социально-экономического развития России - от встраивания в западную цивилизацию во главе с США к суверенному развитию на основе и в русле народно-государственных интересов со всей остротой, в масштабах страны и на всех уровнях воспроизводственного процесса встает проблема кардинального преобразования кадрового потенциала сферы организации и управления народным хозяйством (здесь необходимы поиск новых подходов и выработка неординарных решений). В статье представлена оригинальная авторская концепция преображения кадрового потенциала сферы организации и управления народным хозяйством, исходя из жизненной необходимости синергии безопасности и прогресса экономики: без обеспечения безопасности прогресс превращается в построение здания без фундамента на песке, а безопасность, не подкрепленная качественно и количественно прогрессом, в условиях инновационного развития человеческой цивилизации не осуществима. Речь идет о запуске цепной реакции ревоэволюционного обновления кадрового потенциала. Определено основное диалектическое противоречие воспроизводства и задействования кадрового потенциала. Представлен и обоснован комплекс практических рекомендаций по преобразованию кадрового потенциала сферы организации и управления народным хозяйством.
Mediaactivity as an indicator of the effectiveness of the university
Authors:   Российский экономический университет им. Г.В. Плеханова, МИТЯЕВА О.А. , ИЛЬЯШЕНКО С.Б. ,   Российский экономический университет им. Г.В. Плеханова
Published: August 2023

В статье проанализированы процессы маркетизации и медиатизации рынка образовательных услуг. По результатам изучения теоретической сущности данных явлений авторами обосновано их определяющее воздействие на формирование современных тенденций развития коммуникационной политики вузов. Сформулированы цели и базовые принципы построения эффективной информационной политики образовательной организации, подробно проанализированы специализированные рейтинги, оценивающие медиаактивность как показатель эффективности деятельности российских вузов.
The evolution of paradigms of consumer behavior in the digital age
Authors:   Российский государственный социальный университет, ШЕВЧЕНКО Д.А.
Published: August 2023

В статье проанализирована эволюция парадигм потребительского поведения под воздействием информационных технологий. Предпринимается попытка спроектировать будущее поведение потребителей в динамично развивающемся цифровом пространстве.
Digitalization of small business in Russia: problems and prospects
Authors:   Финансовый университет при Правительстве РФ, ХОНЧЕВ М.А.
Published: August 2023

В статье рассматриваются вопросы определения сущности и значения малого бизнеса для экономики, выявления сложностей его цифровизации, оценки степени внедрения цифровых технологий в малом бизнесе в России. Особое внимание в рамках исследования уделяется проблемам стимулирования активного развития цифровизации малого бизнеса.
Justification of the adjustment of business valuation methods in the conditions of sanctions restrictions (on the example of the timber industry)
Authors:   Финансовый университет при Правительстве Российской Федерации, ГУЛЕВИЧ И.И.
Published: August 2023

В статье на примере лесопромышленного комплекса рассматриваются практические аспекты формирования стоимости бизнеса с учетом санкционных экономических ограничений.
Efectividad de un programa multidisciplinario de tratamiento de la obesidad durante la pandemia de COVID-19
Authors: Tomiazzi Utrila Raquel , da Silva Alexandrino Wesley Gabriel , Westphal-Nardo Greice , Costa Borim Christinelli Heloá , Aparecida de Souza Andressa , Candido Ieda Carla , Nardo Junior Nelson , Molena-Fernandes Carlos Alexandre
Published: August 2023

Objetivo: Evaluar la efectividad del monitoreo remoto de enfermería, en asociación con un programa multiprofesional de tratamiento de la obesidad, para mejorar los biomarcadores cardiometabólicos y los indicadores de aptitud física relacionados con la salud en adultos obesos durante la pandemia de COVID-19.Métodos: Se llevó a cabo un Ensayo Clínico Pragmático en un municipio del sur de Brasil, con la participación de 22 mujeres de edades comprendidas entre los 18 y 50 años, que contaban con teléfonos móviles con acceso a la aplicación WhatsApp® durante un período de 16 semanas. Se realizaron evaluaciones pre y postintervención mediante exámenes de laboratorio, que permitieron determinar los biomarcadores cardiometabólicos: HDL, triglicéridos, LDL, colesterol total, glucemia, hemoglobina glucosilada, insulinemia, Homa-IR, Homa-β, hs-CRP; y pruebas para evaluar los niveles de aptitud física relacionados con la salud: composición corporal, aptitud cardiorrespiratoria, fuerza muscular y flexibilidad. Los datos obtenidos se analizaron utilizando la prueba t para muestras pareadas y se correlacionaron mediante la correlación de Pearson, a partir del valor delta absoluto de cada variable. Se consideraron resultados significativos cuando el valor de p fue < 0,05. Este estudio recibió la aprobación del Comité Nacional de Ética en Investigación.Resultados: Se observaron mejoras significativas en los niveles de glucosa en sangre, insulina, Homa-IR y HDL, así como en los indicadores de aptitud cardiorrespiratoria y fuerza muscular. Conclusión: El monitoreo remoto de enfermería, en asociación con un programa multidisciplinario de tratamiento de la obesidad, resulta en una intervención eficaz para mejorar los biomarcadores cardiometabólicos y los indicadores de aptitud física relacionados con la salud.
Memorias del CGH
Authors: Arreola José
Published: August 2023

Reseña del libro:

Pacheco, A., Mendoza, J. y González, R. (Coords.). (2022). Memorias del CGH: a 20 años de la huelga en la UNAM. México: CNDH.
Antegrade extraperitoneoscopic revascularization of the penis in the treatment of vasculogenic erectile dysfunction.
Authors:   FMBC them. A.I. Burnazyan FMBA of Russia, Mustafaev A.T. , Kyzlasov P.S. ,   center of urology and andrology FMBC them. A.I. Burnazyan FMBA of Russia, Abuev G.G. ,   department of urology and andrology FMBC them. A.I. Burnazyan FMBA of Russia, Volokitin E.V. ,   department of urology and andrology FMBC them. A. I. Burnazyan FMBA of Russia
Published: August 2023

Introduction. Erectile dysfunction (ED) is a multifaceted and widely prevalent problem in modern medicine. The problem of erectile dysfunction has not only medical but also social significance – the presence of erectile dysfunction in men has a deleterious effect on their quality of life. One of the few pathophysiologically substantiated surgical methods of treatment for vasculogenic erectile dysfunction is penile revascularization. Objective. To evaluate the effectiveness of antegrade extraperitoneoscopic penile revascularization in patients with vasculogenic erectile dysfunction, to develop an algorithm for selecting patients with vasculogenic ED suitable for penile revascularization surgery. Materials and methods. From 2015 to 2022, 65 penile revascularizations were performed in patients with vasculogenic ED. All patients were divided into 2 groups. In the main group, antegrade extraperitoneoscopic penile revascularization was performed in 34 patients, while in the control group, penile revascularization was performed in 31 patients according to the Virag-Kovalev method. To assess the results of the treatment, we used the scales and questionnaires IIEF-5, QoL, and the evaluation of penile rigidity on the Erection Hardness Score (EHS) scale. We also compared the duration of surgery and length of hospital stay. Results. The duration of surgery in the main group was significantly shorter (p <0.01) than in the control group. Additionally, the length of postoperative hospital stay was significantly shorter (p <0.05) in the main group. When comparing patients, there was a significant statistical difference in IIEF-5, EHS, and QoL scores. Conclusions. Penile revascularization, particularly the antegrade revascularization method, is an effective method for treating ED. The proposed methodology, based on the shortcomings of previous methods, is the most effective and least invasive of all the presented options. The success of penile revascularization surgery directly depends on careful patient selection and surgeon experience.
The use of recombinant FSH in the treatment of infertility associated with a high level of sperm DNA fragmentation.
Authors:   Sechenov University of the Ministry of Health of Russia, Olefir Yu.V. ,   Moscow, Russia, Monakov D.M. ,   National Medical Research Center of Surgery n.a. A.V. Vishnevsky of the Ministry of Health of Russia; assistant of the Department of Urology and Surgical Nephrology, RUDN University of Russia; Moscow, Russia, Rodionov M.A. ,   New Life IVF clinic; Moscow, Russia, Zhivulko A.R. ,   Center of Immunology and Reproduction; Moscow, Russia, Vinogradov I.V. ,   Department of Urology and Surgical Nephrology, RUDN University of Russia; Moscow, Russia, Popov D.M. ,   Centre of Urology, Nephrology and Lithotripsy, Clinical hospital «RZD-Medicine» n.a. N.A. Semashko; Moscow, Russia
Published: August 2023

Introduction. Male infertility, caused by a high level of sperm DNA fragmentation, remains one of the significant problems of reproductive medicine. One of the methods to overcome it may be the use of recombinant follicle-stimulating hormone (FSH), but the results of studies on this issue are ambiguous. The purpose of this literature review is to systematize publications on this issue. Materials and methods. The search, analysis and systematization of publications in the databases PubMed, eLibrary.ru, Clinicaltrials.gov were carried out using the keywords «male infertility», «sperm DNA fragmentation», «treatment», «follicle stimulating hormone», «FSH». Seventy six publications were selected and included in this review. Results and discussion. The integrity of the genetic material of the sperm is one of the prerequisites for the formation of a normal embryo. Its damage occurs in two main ways: induction of apoptosis and direct damage to DNA by reactive oxygen species. FSH stimulates spermatogenesis and also prevents the induction of spermatozoa apoptosis through the activation of protein kinase B/AKT. Also FSH regulates chromatin packing and increases the ability of spermatozoa to bind to hyaluronic acid. Its use in infertile men led to an improvement in the morphological parameters of spermogram, sperm motility, a decrease in the level of sperm DNA fragmentation, however, the data obtained are difficult to compare due to the heterogeneity of the patient groups included in the study, the lack of standardization of methods for studying the level of sperm DNA fragmentation and using its different threshold values. Conclusions. Therapy with recombinant FSH is one of the promising methods for overcoming infertility in patients with a high level of sperm DNA fragmentation. The heterogeneity of published studies does not allow to draw unambiguous conclusions regarding its effect on the integrity of the genetic material of spermatozoa. Future studies need to use strict inclusion criteria, such as thresholds for the level of sperm DNA fragmentation and the results of a pharmacogenetic study.
Fetomaternal outcome in pregnant patients with fibroids at a tertiary care hospital.
Authors: Iram Aslam  , Nadia Sharif  , Saima Qureshi  , Uzma Manzoor  , Saadia Bano  , Uzma Shahzad
Published: August 2023

Objective: To determine frequency of adverse pregnancy outcomes in patients presenting with uterine fibroids at a tertiary care hospital. Study Design: Descriptive Cross Sectional. Setting: Department of Obstetrics and Gynecology, Independent Medical Collage, Faisalabad. Period: January 2021 to December 2022. Material & Methods: A descriptive cross sectional study was performed over a period of two year from January 2021 to December 2022 at Obstetrics and Gynecology department of Independent University Hospital, Faisalabad. Results: Among total 48 patients of our study 7 patients were aged <20 while 18 were between 20 to 30 years of age and 23 were in 30 to 40 yr age group. Out of 48 patients, 27 were primigraidas, 18 patients were in G2 to G4 group and 10 were >G4. Among 48 patients, 8 had body mass index<25 kg/m2.12 patients had BMI between 26-30kg/m2 and 28 patients had BMI>30kg/m2. 7 patients had symptoms <6 months.14 patients had symptoms for more than 6 months but less than 1 yr while 27 patients had symptoms >1 yr. In our study, 6 patients has spontaneous miscarriages. In our study 9 patients had preterm birth and 22 patients needed caesarean section and 10 patients had PPH. Conclusion: Pregnancy in patients with fibroids, should be considered as high risk, as it is associated with adverse pregnancy outcome. So pregnancy has to be cautiously reserved in the antenatal period, through regular follow up, to detect any obstetric complications and so improve the outcome.
EVALUATION OF IRRIGATION SCHEDULE AND TIME OF SOWING FOR MAIZE, BASED ON ECONOMIC INDICES
Authors:   Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641003, RM PANCHANATHAN , D SRINIVASALU REDDY ,   Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641003, S SUBRAMANIAN ,   Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641003, SP PALANIAPPAN ,   Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641003
Published: August 2023

Economic indices were computed from the experimental data obtained from the investigations carried out at Tamil Nadu Agricultural University, Coimbatore during summer and Kharif seasons of 1984 and 1985 in order to find out the influence of agromet factors and irrigation scheduling on the performance of COH 1 maize. The crop supplied with adequate moisture throughout the crop period recorded higher gross and net returns, benefit cost ratio and per day gross return which declined progressively with the level of moisture stress experienced during various growth stages irrespective of the season. Higher values of these indices were registered when the maize crop was sown on December 1 during summer and August during Kharif seasons.
STUDY ON INCOME AND EMPLOYMENT IN KRISHNAGIRI TALUK AMONG RURAL HOUSEHOLDS
Authors:   Assitant Professor, Department of Agricultural Economics, TNAU,Coimbatore 641 003, N.R PADMANABAN
Published: August 2023

In order to assess and analyse the income particulars and employment details of the agricultural labourers, small and marginal farmers in Krishnagiri taluk, a study was undertaken in 1986, which indicated that the average annual income of the family as Rs. 9728, of which 53.77 per cent from crop activities, 19.67 per cent from non-farm activities, 14.56 per cent from off-farm activities and 12 per cent from livestock activities. The average annual employment per family was observed to be 457.30 mandays, of which 38.97 per cent is from off-farm activities, 35.71 per cent from own farm activities and 25.32 per cent from non-farm activities.
GENOTYPIC ASSOCIATION AND PATH ANALYSIS IN F3 GENERATION OF RICE CROSSES
Authors:   Tamil Nadu Agricultural University Coimbatore  641 003 Tamilnadu, J.R KANNAN BAPU , G SOUNDRAPANDIAN ,   Tamil Nadu Agricultural University Coimbatore  641 003 Tamilnadu
Published: August 2023

Genotypic correlation and path co-efficient analyses were carried out in F3 populations of two intervarietal crosses of rice for grain yield and its components. Tiller, number, panicle length and plant height showed positive correlation with grain yield. Hundred grain weight exhibited negative correlation with grain yield. Due stress must be laid on number of productive tillers per plant and panicle length during the selection for higher yield in rice.
PATH COEFFICIENT ANALYSIS IN BLACKGRAM
Authors:   Tamil Nadu Agricultural University Coimbatore  641 003 Tamilnadu, K Renganayaki , S.R Sreerengasamy ,   Tamil Nadu Agricultural University Coimbatore  641 003 Tamilnadu
Published: August 2023

Variability, heritability and genetic advance were estimated for sixteen characters in twenty blackgram (Urd) types. phenotypic and genotypic coefficient of variation for dry leaf weight was high followed by seed yield and leaf area. Genetic advance was high for seed yield followed by dry leaf weight. Seed yield per plant showed significant positive correlation with all the characters except number of primary branches, specific leaf weight and protein per cent. path coefficient analysis revealed plant height and primary leaf area had higher positive direct effect on seed yield and 100 seed weight recorded highest negative direct effect on seed yield.
INFLUENCE OF TIME OF FORAGE CUTTING ON SEED YIELD AND QUALITY OF LUCERNE (Medicago sativa L.) Cv CO 1
Authors:   Tamil Nadu Agricultural University Coimbatore  641 003 Tamilnadu, A JACQUELINE SELVARAJ , P SRIMATHI ,   Tamil Nadu Agricultural University Coimbatore  641 003 Tamilnadu
Published: August 2023

A field study involved 12 treatments represented by 12 monthly forage cutting given to the seed crop of cv Co 1 lucerne viz. during February 1980 (M1), March 1980 (M2), April 1989 (M3), May 1980 (M4), June 1980 (Ms), July 1980 (M6). August 1980 (M7), September 1980 (M8), October 1980 (M9), November 1980 (M10), December 1980 (M11) and January 1981 (M12).
GENETIC ARCHITECTURE OF YIELD AND QUALITY CHARACTERS IN GROUNDNUT
Authors:   Assitant Professor, Agricultural Research Station,Aliyarnagar 642 101, P VINDHIYA VARMAN , K PARAMASIVAM ,   Assitant Professor, Tamil Nadu Rice Research Institute, Aduthurai - 612101, Tamil Nadu
Published: August 2023

Analysis of generation means was carried out in six crosses involving two cultivated varieties and three-exotic rust resistant cultures of groundnut (Arachis hypogaca.L) for pod yield and quality characters viz. Shelling percentage, Hundred kemel weight and Sound mature kernel percentage. The data revealed considerable proportion of non-allelic interactions. All characters were found to be controlled by both additive and non-additive gene action, however, in the case of shelling percentage predominance of non-additive gene action was observed.
FIELD SCREENING OF SHORT DURATION PIGEONPEA LINES FOR RESISTANCE TO BACTERIAL LEAF SPOT AND STEM CANKER (Xanthomonas campestris pv. cajani)
Authors:   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, G ARJUNAN , R SAMIYAPPAN ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, K THIYAGARAJAN ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai
Published: August 2023

Thirty five determinate and non-determinate pigeonpea types of early duration were screened against bacterial leaf spot and stem canker (Xanthomonas campestris pv. cajani). ICPL 87 and ICPL 85017 in determinate and ICPL Nos. 84048, 85048, 85049 and ICPH.22 in non-determinate types were resistant to bacterial leaf spot. Among these lines, the non-determinate line ICPL 85049 showed resistant reaction to stem canker also. The other five lines showed moderate resistance to stom canker. In general, red-flowered types, whether determinate or non-determinate, were found more susceptible than yellow-flowered types.
LOSS DUE TO LEAF CURL AND SPOTTED WILT DISEASES OF TOMATO
Authors:   Department of Plant pathalogy, C.S Azad University of Agriculture & technology, Kanpur 208 002, B.R SINGH , D.P TRIPATHI ,   Department of Plant pathalogy, C.S Azad University of Agriculture & technology, Kanpur 208 002
Published: August 2023

Trends on incidence and losses due to leaf curl (LCD) and spotted wilt (SWD) diseases of tomato in relation to their vectors were studied at Kanpur, India. The population of whitefly and thrips on tomato was found to be maximum respectively in February and March. The incidence of LCD was found maximum in January and February while that of SWD in March. The losses due to LCD were the reduction in plant height, number of fruits and fruit weight, while SWD, in addition, killed the plants resulting in total loss. The average yield loss/ha was 163.68 q and 126.12 q or Rs. 8184 and 6306 due to LCD and SWD respectively.
POST INFECTIONAL CHANGES IN GROUNDNUT LEAVES IN- DUCED BY GROUNDNUT BLIGHT PATHOGEN
Authors:   Department of Plant Pathology,Tamil Nadu Agricultural University Coimbatore  641 003, P BALASUBRAMANIAN , P NARAYANASAMY ,   Department of Plant Pathology,Tamil Nadu Agricultural University Coimbatore  641 003
Published: August 2023

Post-infectional change in contents of total carbohydrate, total nitrogen, total phenolics, nucleic acids and chlorophyll fractions in the leaves of three groundnut genotypes with varying levels of resistance to blight caused by Phoma microspora Balasubrm, et Narayan., was studied. Total carbohydrate contents of the resistant variety, Ah 8446 and the tolerant variety, POL 2 showed only a marginal variation, while the highly susceptible OSN 2 registered significant increases. There was no appreciable change in total nitrogen content in the resistant variety consequent on inoculation. Increase in the total phenolics contents was significantly greater in the highly susceptible OSN 2 than others. There was no significant alteration in the contents of RNA and DNA in the resistant and tolerant varieties while reduction in the contents of chlorophyll was maximum in the highly susceptible variety.
RECYCLING OF POULTRY WASTE IN INTEGRATED FISH FARMING
Authors:   Fresh Water Biological Research Station Bhavanisagar 638 451, M AYYANNAN , A CHELLAKUMAR ,   Fresh Water Biological Research Station Bhavanisagar 638 451, V TAMILMANI ,   Fresh Water Biological Research Station Bhavanisagar 638 451, C UDAYASOORIAN ,   Agricultural Research Station Tamil Nadu Agricultural University, Bhavanisagar 638 541 Tamilnadu.
Published: August 2023

An integrated fish culture experiment with poultry was carried out at fresh Water Biological Research Station, Bhavanisagar during 1986-87. Poultry droppings were added in the experimental pond at the rate of 8 t/ha/ycar instead of supplementary feeding and manuring. The fish species Viz., Catla, Rohu, Mrigal and Common carp in the ratio of 3:2:2:3 were stocked at the rate of ten thousand numbers per hectare. A total production of 4125 kg of fish/ha/year was recorded in the experimental pond against 3500 kg in control pond. The increase in yield being 18 per cent over control. The production cost per kg of fish was reduced from Rs. 5.75 in the control to 2.00 in experimental pond. In addition, the fertility status of the experimental pond was also improved.
CHANGES IN AVAILABLE NPK STATUS AFTER 8 YEARS OF CONTINUOUS MANURING AND FERTILIZATION IN RICE-RICE CROPPING SYSTEM
Authors:   Dept.of Soil Science and Agrl,Chemistry  University Tamil Nadu Agricultural University Coimbatore  641 003, C UDAYASOORIAN , . PARAMASIVAM ,   Dept.of Soil Science and Agrl,Chemistry  University Tamil Nadu Agricultural University Coimbatore  641 003
Published: August 2023

The influence of long term fertilization with organic manure and inorganic fertilizers under Rice-Rice cropping system on the available NPK status was investigated in the permanent manurial experimental plots of Agricultural College farm, Madurai. Continuous addition of FYM along with NPK fertilizers for eight years resulted in higher available N and P content while addition of compost along with K fertilizer resulted in higher available K content. Accumulation of more of available NPK was observed in the surface soil than sub surface soil. Addition of Nhad a depressive effect on the available K status of soil.
DIRECT AND RESIDUAL EFFECT OF FYM AND NPK LEVELS ON SUNFLOWER
Authors:   Agricultural Research Station Tamil Nadu Agricultural University, Bhavanisagar 638 541 Tamilnadu., C UDAYASOORIAN , P BALAMURUGAN ,   Agricultural Research Station Tamil Nadu Agricultural University, Bhavanisagar 638 541 Tamilnadu., P MUTHUVEL ,   Agricultural Research Station Tamil Nadu Agricultural University, Bhavanisagar 638 541 Tamilnadu.
Published: August 2023

Field experiments conducted in a red sandy loam soll to investigate the direct and residual effect of FYM and NPK fertilizers on sunflower revealed that application of FYM at 20 t/ha with 50% of recommended NPK fertilizer increased the seed yield of direct and residue crops. The yield reduction in residue crop under FYM and NPK treatments was only 18 to 19 per cent as against 21 to 28 per cent under no FYM and no NPK treatments. The reduction in oll yield in the residue crop was 21.8%.
EFFECT OF SILICATE MATERIALS ON INCIDENCE OF RICE PESTS
Authors:   Assitant Professor, Department of Soil Science, Agricultural College & Research Station Madurai, S SUBRAMANIAN , A GOPALSWAMY ,   Assitant Professor, Department of Soil Science, Agricultural College & Research Station Madurai
Published: August 2023

A field experiment was conducted to find out the effect of various sources of silicate materials on yield, Si content and incidence of rice crop pests. Applied silicate materials significantly increased the yield and Si content at all stages and reduced the incidence of rice pests viz., thrips (Stenchnetothrips biformis Bagnall), gall-midge (Orseolla oryzae Wood-Mason) and leaf folder (Cnaphalocrocis medinalis Guen.).
INFILTRATION'- A MULTI FACTOR PHENOMENON
Authors:   Assitant Professor, Dept of Soil and Water Conser Engg,Tamil Nadu Agrl University,Coimbatore 641003.Tamilnadu, C MAYILSWAMI , D CHANDRASEKARAN ,   Professor and Head, Dept of Soil and Water Conser Engg,Tamil Nadu Agrl University,Coimbatore 641003.Tamilnadu
Published: August 2023

To understand the complex phenomenon that infiltration is, experimental studies were conducted with treatments of tillage, manure application, vegetative growth and root develop- ment of coconut trees. It is gathered, that these treatments enhance the Infiltration rates. Suitable soll management conclusions are arrived at.