bluuebunny/crossref_metadata_2025 huggingface dataset:
Современная система финансового планирования в организациях
Authors: Попова О.Д.
Published: February 2024

В статье рассмотрены основные понятия, связанные с финансовым планированием в организациях, приведены примеры осуществления финансовых стратегий и дана характеристика методов и инструментов финансового планирования.
Современная банковская система Российской Федерации и пути ее улучшения
Authors: Рощектаева У.Ю. , Сахацкая Э.С.
Published: February 2024

В статье рассмотрена современная банковская система Российской Федерации, представлены ее особенности и преимущества, найдены возможные направления для улучшения ее деятельности.
Проблемы налоговой системы РФ и пути ее совершенствования
Authors: Салдаева Д.С.
Published: February 2024

В статье рассмотрена сущность налоговой системы. B работе указан анализ текущих проблем налоговой системы РФ. Изучены особенности налоговой системы в России, изложены ее функции и структура. B статье рассмотрены основные проблемы налоговой системы Росси. Также указаны возможные пути ее совершенствования.
Специфика управления оборотными средствами предприятия
Authors: Синекопова И.В.
Published: February 2024

В данной статье мы рассмотрим основные аспекты оборотных средств предприятия, их значимость для успешного ведения бизнеса и факторы, влияющие на эффективность их использования, а также дадим рекомендации по оптимальной стратегии управления этими активами.
Проектный менеджмент в управлении вузом: опыт применения
Authors: Солтис В.В
Published: February 2024

Применение проектного подхода в управлении способствует росту инновационного потенциала образовательной организации и является одним из условий позитивной динамики качества управления образовательными системами в условиях устойчивого социальноэкономического, общественного развития и модернизации сферы образования. В работе приведено теоретическое и практическое обоснование основных подходов построения системы проектного управления вузом, рассмотрены методические основы создания в образовательном учреждении системы стратегического управления и проектного менеджмента. Работа содержит результаты методического подхода к формированию механизмов управления, основанных на инструментах проектного менеджмента в образовательной организации высшего образования.
Российский рынок акций и его функционирование в современных условиях
Authors: Сукаева А.С. , Онопко В.В. , Кузьмина О.Ю.
Published: February 2024

Непростые условия существования российской экономики на мировой арене значительно повлияли на российский фондовый рынок, в том числе на рынок акций. В статье рассматриваются ключевые проблемы развития российского рынка акций в условиях санкционного давления, оцениваются перспективы роста данного финансового сегмента экономики.
Персонифицированные сведения о физических лицах содержание, понятие и отчетность
Authors: Тамбиева А.Х-М. , Лайпанова З.М.
Published: February 2024

Пенсионный фонд, фонд соцстраха объединяются в единый Социальный фонд России. И поэтому произойдут изменения в составе отчѐтности: некоторые бланки будут отменены, другие — обновлены. Появятся новые отчѐты, например ―Персонифицированные сведения о физических лицах‖, который заменит собой СЗВ-М.
Проблематичность перехода на мсфо 17
Authors: Тамбиева А.Х-М. , Эльгайтарова Н.Т.
Published: February 2024

В связи с пересмотром и обновлением требований МСФО 17 «Договоры страхования» дата вступления Стандарта в силу была перенесена на 1 января 2023 года. Из всех проблем, связанных с внедрением МСФО (IFRS) 17, переходный период является вопросом, связанным с наибольшей неопределенностью для руководства.
О доходах организации и факторах их повышения в современных условиях
Authors: Тимиряева Л.Ф.
Published: February 2024

В статье раскрыта классификация факторов, которые влияют на процесс получения дохода организации. Рассмотрены критерии, по которым можно оценить тот или иной фактор, а также как его можно применить в деятельности организации. Рассмотрены ситуации, при которых можно раскрыть особенности факторов.
Анализ финансовых результатов
Authors: Тхагапсова С.К-Г. , Гебенова А. , Асланова Д.
Published: February 2024

Финансово-экономический анализ, или мониторинг финансового положения, – это расчет и трактовка коэффициентов, которые позволяют оценить способность фирмы осуществлять свои обязательства и прогрессировать. Задача экономического анализа – получить информацию для принятия организационных решений.Основными инструментами проведения комплексного финансового анализа хозяйствующего субъекта, а также оценки ее коммерческой деятельности выступает анализ состава и структуры бухгалтерского баланса, расчет коэффициентов ликвидности, рентабельности, деловой активности и финансовой устойчивости предприятия.
Инвестиционный менеджмент в период кризиса
Authors: Усманов Д.Р. , Семенов Р.Е. , Сорокина К.В.
Published: February 2024

Если исходить из того, что нынешняя экономическая ситуация соответствует рыночным принципам, то для стимулирования и регулирования инвестиций необходимо привлекать вклады, ресурсы и создавать благоприятные условия для инвестиций. В особенности, в периоды кризиса нам приходится сталкиваться с необходимостью эффективного планирования инвестиций и принятия обоснованных решений по вложениям для поддержания бизнеса, улучшения его кредитоспособности и финансовой стабильности. Эта статья дает определение кризиса и инвестиционной стратегии. Инвестиционная деятельность является важной составляющей развития бизнеса на любом этапе. В статье подробно описывается процесс принятия инвестиционных решений во время кризиса, включая характеристику каждого этапа. Также рассматривается опыт мировых инвестиций в условиях кризиса. Для инвестиционных проектов, финансируемых акционерами, кризис становится ограниченным или несуществующим источником финансирования. Во время кризиса выживание компании всецело зависит от государственного участия в ее финансовой деятельности и проектах. Это создает значительные трудности во время кризиса, однако это возможно. По этой причине тема управления инвестициями в условиях кризиса всегда актуальна, независимо от сферы деятельности компании, ее размера и внешних факторов.
Формирование цифровой экономики в России
Authors: Фецюх Я.А. , Филина О.В.
Published: February 2024

Данная статья посвящена исследованию формирования цифровой экономики в России. Рассказывается о ее сущности, особенностях, проблемах цифровой экономики на сегодняшний день.
Влияние технологии искусственного интеллекта на экономическое развитие и экономику России
Authors: Филина О.В. , Баглаева Э.А.
Published: February 2024

В данной статье рассматриваются все возможные аспекты влияния применения технологий искусственного интеллекта в контексте существующих положительных эффектов и прогнозирования развития в будущем. Рассмотрено влияние на ключевые экономические показатели и сферы применения искусственного интеллекта, неизбежно ведущие нас к радикальной реструктуризации в мировой экономике, посредством применения комплекса инструментов обработки процессов производства, оказывающие влияние на подход к работе большого кластера специальностей и ведения разнообразного бизнеса.
Сущность и роль налогов в формировании доходов государственного бюджета
Authors: Хамурадов М.А
Published: February 2024

Данная научная статья посвящена анализу налоговых поступлений в федеральный бюджет за последние годы и на основе проведенного анализа определению проблем в налоговой системе страны и предложению мер, направленных на повышение эффективности налоговой политики страны на основе ранее проведенного анализа налоговых поступлений в федеральный бюджет. К мерам повышения эффективности налоговой системы отнесено реформирование налоговой системы страны с использованием прогрессивной шкалы налогообложения, изучение и применение опыта развитых стран в сфере определения минимума доходов, для граждан неподлежащих налогообложению и т.д.
История становления системы налогообложения в Российской Федерации
Authors: Хасанова С.С. , Орсаханов Д.У. , Сайдулгериева М.А.
Published: February 2024

Налогообложение является важным условием существования государства, поскольку оно обеспечивает возможность выполнять все функции, которые на себя берет государство. Оборона страны, защита населения, оказание ему помощи, поддержка слабых и незащищенных слоев населения, обеспечение здравоохранения и образования, поддержка государственного аппарата; выполнение перечисленных функций обязательно требует финансовых ресурсов, аккумуляцию которых как раз-таки обеспечивает налоговая система.
Налоговая политика как инструмент государственного регулирования
Authors: Хасанова С.С. , Орсаханов Д.У. , Сайдулгериева М.А.
Published: February 2024

Налоговая система при грамотном построении является надежной опорой для экономики страны. Реализация налоговой политики происходит через совокупность законов и нормативно-правовых актов. Принципы налоговой политики в государстве определяются приоритетами его внутренней и внешней политики, состоянием экономики и перспективными направлениями развития. Налоговая политика отражает цели воздействия государства на экономику, и в зависимости от состояния экономики, степени государственного вмешательства уровень централизации средств может меняться.
Проблемы и перспективы развития бизнеса в России
Authors: Хасанова С.С. , Орсаханов Д.У. , Сайдулгериева М.А.
Published: February 2024

Предпринимательство в государстве имеет значимую роль в социально-экономическом развитии, что обусловливает особое внимание со стороны государства к данной сфере деятельности. В России институт предпринимательства является относительно молодым, что опосредует необходимость в совершенствовании условий его функционирования. В статье рассматриваются проблемы и анализируется современное состояние развития предпринимательства.
Экономическая сущность и назначение косвенных налогов
Authors: Хасанова С.С. , Сайдулгериева М.А.
Published: February 2024

Налоги являются неотъемлемой частью государственного уклада современных государств. Налоговые системы прошли эволюционирование от древних государств до сегодняшних дней. Можно смело утверждать, что налоги являются, хоть и специфическим, но весьма естественным результатом эволюции государственности и экономической мысли в мире. В статье рассматриваются акцизы и НДС, как косвенные налоги, действующие в РФ в настоящее время.
Цифровая трансформация сельского хозяйства
Authors: Шувалов Е.А.
Published: February 2024

Цифровая трансформация сельскохозяйственных организаций требуется для повышения эффективности работы и устойчивости его функционирования за счет изменения организации управления? как технологическими процессами, так и процессами принятия решений на всей вертикали управления в АПК. Сегодняшние темпы технологических разработок, роботизации и внедрение цифровых технологий способствуют развитию сельскохозяйственной техники, машин и оборудования. Внедрение цифровых технологий в агропромышленный комплекс позволяет повысить эффективность управления в отрасли, скорость оборота капитала, повысить эффективность использования ресурсов, прозрачность процессов предоставления мер господдержки, сократить затраты сельскохозяйственных организаций и фермерских хозяйств на предоставление отчетности.
Учетная политика в системе учетно-аналитического обеспечения бизнеса
Authors: Эппингер Е.Н. , Тарасенко О.Н.
Published: February 2024

В статье анализируется влияние управленческого аспекта учетной политики в системе учетноаналитического обеспечения бизнеса на предприятии.
Издержки и себестоимость производства на предприятиях энергетики
Authors: Якупова А.Б. , Ялалова З.Р. , Нигматзянова Л.Р.
Published: February 2024

Энергетика сегодня играет важнейшую роль в нашей жизни, обеспечивая электроэнергией наши дома, предприятия и общественные учреждения. Различные формы производства энергии, такие как теплоэнергетика, электроэнергетика и ядерная энергетика, требуют значительных финансовых вложений и регулярного обслуживания. В данном тексте мы рассмотрим основные издержки и себестоимость производства на предприятиях энергетики.
Механизм поддержки зеленого развития предприятий
Authors: Яндарбаева Л.А. , Костоева А.А. , Боков С.В.
Published: February 2024

На сегодняшний день «зеленое» развитие является неизбежным выбором многих предприятий. Содействие зеленому развитию предприятий нуждается не только в государственном, но и в рыночном механизме. Что касается экономического развития и социального прогресса, содействие зеленому развитию предприятий с помощью рыночного механизма является необходимым способом рыночной экономики.
Экологическое управление предприятием
Authors: Яндарбаева Л.А. , Костоева А.А. , Боков С.В.
Published: February 2024

Данная статья посвящена теме экологического управления предприятия. Она анализирует важность экологического управления в современном бизнесе и исследует его основные аспекты. Статья подчеркивает необходимость изучения воздействия предприятия на окружающую среду и выявления потенциальных рисков. Также статья указывает на важность разработки и реализации экологической политики, включающей цели и обязательства предприятия по экологической ответственности.
Влияние предпринимательской ориентации на организационную устойчивость
Authors: Яндарбаева Л.А. , Костоева А.А. , Джабраилова Л.Х.
Published: February 2024

Статья посвящена анализу организационно-экономической устойчивости предприятий как фактору эффективного управления, эффективного конкурентоспособного существования на рынке товаров и услуг. Описаны внешние факторы, такие как экономическая и политическая нестабильность, которые влияют на деятельность предприятий. Рассмотрены ключевые качества организационной устойчивости.
The impact of Chinese-Russian intercultural exchanges on the «One Belt One Road»
Authors: Wang X.
Published: February 2024

The ―One Belt, One Road‖ initiative is an international initiative implemented by China and aimed at developing economic, political and social cooperation with the countries of Eurasia. As a result of the development of cultural exchange between China and Russia, this project has a great impact. The study analyzes the impact of Chinese and Russian diplomatic exchanges on various aspects of the Belt and Road Initiative. It examines the economic, cultural, social and political aspects of cooperation between the two countries. The emphasis is on the influence of ChineseRussian cultural exchange on the development of trade and economic relations, the creation of new regional projects and the strengthening of national security. ChinaRussia public exchanges will help strengthen relations between the two countries, improve mutual understanding and expand cooperation in various fields
EXPERIENCE IN USING IMPLANTS WITH A SLOPED PLATFORM EDGE
Authors: Samsonov Andrey , Ashurko Igor , Tarasenko Svetlana , Tumanova Elizaveta , Abakarov Magomed
Published: February 2024

Purpose: Comparative analysis of the use of implants with modified neck configuration and standard implants with additional bone grafting.

Materials and methods: 34 patients with partial tooth loss combined with a horizontal defect of the alveolar bone were included in the study. In group 1 (n = 15) implants with sloped platform edge were placed, in group 2 (n = 19) implants of standard design with directed bone regeneration (GBR) were placed. The primary end point of the study was the level of vertical bone resorption in the implant neck area 6 months after the operation. Secondary endpoints were: pain (VAS) and oedema scores, width of attached gingiva, number of analgesics taken, quality of life and health (OHIP-14).

Results: The level of vertical resorption after 6 months in patients in group 1 was 0.04 ± 0.04mm mesially and 0.06 ± 0.05mm distally, in patients in group 2 mesially 1.06 ± 0.35mm and distally 1.00 ± 0.39mm. The use of implants with sloped edge of the platform was characterized by lower pain intensity the first 7 days after surgery (p < 0,001), lower severity of collateral edema (p < 0,001), lower consumption of NSAIDs on 1, 3, 5, 7 days (p = 0,002, <0,001, <0,001 and 0,008, respectively), lower total OHIP-14 score (p = 0,047) on 7 days. After 4 months, the width of attached keratinized gingiva was 3.6 (3–3.8) mm in patients in group 1 and 2 (1.5–2.1) mm in group 2.

Conclusion: The use of implants with a sloped platform edge is characterized by a lower level of vertical resorption and allows for a more comfortable postoperative period.
STUDY OF THE SPATIAL ACCURACY OF JAW MODELS DEPENDING ON THE METHOD OF OBTAINING AN IMPRESSION AND ITS MATERIAL
Authors: Koshelev konstantin , Belousov Nikolay , Zobacheva Valentina , Zobachev Vitaly , Kostin Igor
Published: February 2024

Methods for obtaining working and auxiliary dental impressions of patients have been revised in recent decades, which is associated with 3D scanning. At the same time, the policy of import substitution in dentistry is also developing quite actively, which is reflected in the introduction of domestic impression masses for analog prints into public health institutions.

The aim of study. Reducing the number of complications of dental orthopedic treatment by optimizing the approach to choosing a method for obtaining a working anatomical impression.

Methodology. Impressions of the mandible of 10 patients were obtained. 7 impressions were obtained from each patient using the most commonly used techniques, silicone impression materials and intraoral scanning. Further, jaw models of 4 types of plaster were made for each impression and scanned with an off-site dental scanner. With the help of a micrometer in the oral cavity, measurements of teeth 3.5, 4.4 and 4.2 were made according to the maximum vestibular-oral size of the clinical crown, which were taken as a standard. The reference size is compared with the dimensions obtained on digital models according to the selected parameters with an accuracy of up to thousandths of a millimeter. A statistical analysis of the data obtained was carried out.

Results. The data obtained confirmed the manufacturer's claims about the accuracy of the impression masses. A slight decrease in the studied sizes was noted on the models obtained by intraoral scanning. Whereas on models obtained using silicone impressions, the dimensions, on the contrary, were slightly larger than the reference ones. A statistically significant difference was revealed when comparing models obtained using intraoral scanning and models obtained by laboratory scanning from analogues of jaws using silicone impressions. When comparing the data obtained with the standard, no critical differences were revealed.

Conclusions. It is impossible to unequivocally assert the advantage of a digital or analog method of obtaining impressions in modern orthopedic dentistry. The method of obtaining an impression should be chosen depending on the indications for a particular type of treatment and clinical conditions.
OPTIMIZATION OF THE FINAL STAGE OF ZIRCONIUM DIOXIDE-BASED PROSTHESIS PREPARATION FOR FIXATION IN THE PATIENT’S ORAL CAVITY
Authors: Lebedenko Igor' , Axelrod Igor , Verdiyan Samvel , Shumskaya Djamilya
Published: February 2024

Laboratory study of the acid etching impact on the surface of domestic ceramic translucent zirconium dioxide-based samples by special acid composition has been conducted in order to improve the esthetic qualities of ceramic dentures based on zirconium dioxide as well as to reduce the risk of their breakage and debonding by improving the final treatment methods of the prosthesis surface before fixation in the oral cavity, namely special acid etching of the internal surface and fluorescent glaze applied only to the prosthesis areas visible at a wide smile. The adhesive strength to composite resin cement has been assessed and three different dental fluorescent glazes have been studied for bending strength of zirconium dioxide samples depending on the coating area. The issue of combined effect of the zirconium dioxide-based ceramic’s surface chemical preparation has been studied with a view to increasing both the adhesive strength and the esthetic characteristics. A conclusive reduction in the strength of zirconium dioxide-based ceramic samples after the ceramic coating of each of the studied fluorescent glazes and a significant increase in the adhesive strength of ceramic with composite resin cement after etching with a special composition are shown. To improve the esthetics of zirconium dioxide dental prostheses, prevent the fractures of prostheses and reduce the possibility of their debonding in the oral cavity, it is recommended to apply fluorescent glaze with a minimum sufficient thickness and only on the vestibular and partially occlusal zones, and before fixing to composite resin cement in the oral cavity it is advisable to carry out chemical treatment of the ceramics’ bonded surface with a special etching solution.
DEVELOPMENT OF A COMPUTER EXPERT PROGRAM FOR ASSESSING THE CONDITION OF PERI-IMPLANT TISSUE
Authors: Taghizadeh Javid , Parshin Yuriy , Trezubov Vladimir , Rozov Roman
Published: February 2024

The subject of the research – expert assessment of the quality of implant prosthetics.

The goal – creation of an instrument and clinical testing of the TAPATR computer program for assessing the condition of soft and hard peri-implant tissues, which is a diagnostic, prognostic and control method.

Methodology. The subjects of the study were 48 people (11 men, 37 women) aged from 48 to 65 years (average age 58.2 ± 4.8 years). A comparative assessment of the proposed method (questionnaire) and the X-ray examination method (cone-beam tomography) was carried out. Statistical processing of materials was carried out using SAS v9.4 software.

Results. Successful initial clinical validation of the method was carried out. A comparison of the survey and radiological assessment led to reliably identical results, namely, a direct pattern of deterioration in the health of peri-implant tissues depending on the degree of peri-implantitis. Statistical analysis showed that there are significant correlations between all indicators: between a high level of health and the absence of illness, a good level of health and class 2 illness, (r = 0.42 and r = 0.42, respectively). A moderate correlation has been proven between a low level of health and disease class 2 (r = 0.56) and severe – between a satisfactory level of health and class 3 (r = 0.76).

Conclusion

1. An expert method for assessing the condition of soft and hard peri-implant tissues has been developed.

2. High objectivity, validity and reliability of the presented method have been proven.

3. The proposed method can be used in clinical settings, in expert assessment of the quality of prosthetics, and also in the work of conflict expert commissions.
COMPARATIVE ANALYSIS OF CYTOTOXICITY OF SEALERS FOR ROOT CANAL FILLING (IN VITRO)
Authors: Griroriev Sergey , Kozmenko Anastasia , Gainetdinov Maksim , Kornilov Daniil , Zornikov Danila
Published: February 2024

Endodontics, being a part of the discipline "Dentistry", includes sections on the study of morphology, physiology and pathology of dental pulp and human periapical tissues, as well as the prevention and treatment of diseases and injuries associated with these tissues. Its scope of application includes the diagnosis and treatment of pain of pulpar and/or periapical origin, vital pulp therapy, regenerative endodontic procedures, non-surgical root canal treatment, surgical or non-surgical re-treatment of teeth with persisting infection and intracanal teeth whitening with discoloration. Ultimately, the main goal is to preserve the natural dentition.

Like other dental specialties, endodontics combines two inseparable parts in its practical part: art and science. The art lies in performing technical procedures during root canal treatment. The scientific part includes fundamental and clinical disciplines, studying.

Objectives. To study the cytotoxicity of epoxy resin-based silers in laboratory conditions on human cell lines and conduct their comparative analysis.

Methodology. The article presents an analysis of the results of in vitro cytotoxicity of silers by assessing cell viability with direct injection of the studied materials into human cell culture.

Conclusion. It has been experimentally proven that samples 1 (AH plus, Dentsply Sirona, Germany) and 3 (Epoxidin DUO, TecnoDent, Russia) do not have cytotoxic properties, unlike 2 samples (Sealart, Dentac, Turkey).
DATA ANALYTICS OF SALIVARY STATUS IN STUDENT SMOKERS IN THE COURSE OF USING A MUCOPROTECTIVE SPRAY
Authors: Elovicova Tat'yana , Ermishina Elena , Ssablina Svetlana , Mandra Yuliya , Molvinskikh Vera , Koshchev Anatoly , Shimova Margarita , Ivanova Valeria
Published: February 2024

Subject. The subject of this study is the salivary status in the patients.

Objectives. The objective is to identify specifics of data analytics of the salivary status in student smokers effected by using a mucoptorotective dental spray.

Methodology. The study is made by the Ural State Medical University Department of Preventive Dentistry and Propedeutics of Dental Disease, the Ural State Medical University Department of General Chemistry, the Ural Federal University Department of Control Systems Modeling. The objects of the study are unstimulated mixed saliva and a mucoptorotective spray that helps to protect the oral mucosa against inflammations, facilitates penetration across epithelial membranes, acts as a controlled multifunctional drug delivery system for parodontium tissues. The two study groups were formed from 20 volunteers in the age of 20 to 24 years old (4 women and 36 men, the average age was 22,35 years old): the first (main) group consisted of smoking patients, the second (reference) group consisted of non-smokers. The clinical assessment of the oral cavity of patients included: analysis of complaints, analysis of anamnesis, examination, evaluation of the hygiene index (OHI, Greene, Vermillion, 1964), dental caries severity index (using DMFT and DMFS indices), the state of gingival inflammation, PMA index (Parma). Unstimulated mixed saliva was studied, the quantitative analysis of the secretion was made by analyzing color, transparency, presence of inclusions, pH value, the functional activity of minor salivary glands. The statistical analysis of results was made using a PC with Microsoft Excel 2007 software program; the statistical significance was assessed using Student’s t-distribution by Statistica 6.0 software package.

Conclusions. Given the reduction of objective values of index assessment of oral health status used as indicators of changes in oral health, the study of the data analytics of salivary status in student smokers in the course of using a mucoptorotective spray revealed the harmful effects of tobacco on salivary composition and parameters. The findings prove smoking-related oral homeostatic disruption promoting development and progression of dental diseases of the hard tissues, parodontium, oral mucosa. Application of the dental spray with titanium glycerosolvate aquacomplex is proved to be an effective way to prevent development and progression of such diseases.
RESULTS OF THE USE OF A DIRECTED BIOCORRECTION DRUG AND A DRUG CONTAINING LACTOFERRIN IN THE COMPLEX TREATMENT OF CHRONIC GENERALIZED PERIODONTITIS IN PATIENTS WITH PRIMARY HYPOTHYROIDISM
Authors: Griroriev Sergey , Bushueva Elizaveta , Kozmenko Anastasia , Gainetdinov Maksim , Zornikov Danila
Published: February 2024

Subject In the traditional complex treatment of inflammatory periodontal diseases, antibacterial, antiseptic and anti-inflammatory agents are of paramount importance. These products allow you to obtain not only a positive clinical result, but can also manifest their negative properties, having an ambiguous effect on the microbiome of the oral cavity and periodontal tissue. The use of targeted biocorrection drugs and immunocorrectors has a significant local anti-inflammatory effect with minimal side effects. Their use in the complex treatment of chronic generalized periodontitis has not been studied enough.

Aim. To evaluate the effectiveness of using a targeted biocorrection drug and a phytocomplex with lactoferrin in the complex treatment of chronic generalized periodontitis in patients with primary hypothyroidism.

Material and methods. We observed 90 patients with the main diagnosis of primary hypothyroidism aged 44–59. The patients were divided into 3 groups: in group No. 1, 30 patients received traditional primary periodontal therapy, in group No. 2, 30 patients in whom this therapy was combined with a directed biocorrection drug, in group No. 3, 30 people for whom traditional primary periodontal therapy was combined with a directed biocorrection drug and a drug containing lactoferrin. The comparison group included 30 gender and age-matched patients with chronic generalized periodontitis without thyroid pathology. All patients underwent clinical, X-ray and index evaluation of periodontal tissues.

Results. In patients of group No. 1, after traditional treatment, clinical and index evaluation data indicated the persistence of inflammatory processes in periodontal tissues. In groups No. 2 and No. 3 on the background of traditional treatment and additionally administered.

Conclusions. The addition of a traditional treatment regimen for chronic generalized periodontitis with a targeted biocorrection drug and a drug containing lactoferrin is justified and effective.
EXPERIMENTAL RATIONALE FOR THE APPLICATION OF BIORESORBABLE PERSONALIZED COLLAGEN MEMBRANES FOR CLOSURE OF DEFECTS IN THE ORAL MUCOSA
Authors: Gostev Mikhail , Tarasenko Svetlana , Kazumyan Sabina , Diachkova Ekaterina , Usanova Anna , Fayzullin Alexey , Timashev Petr , Sadchkova Elena
Published: February 2024

Subject. The subject of the study is the biomechanical properties of a personalized collagen membrane in the area of wound defects of the oral mucosa.

Objectives. To increase the effectiveness of treatment of patients with extensive surgical wound defects of the oral mucosa by experimentally substantiating the use of developed collagen membranes from bovine Achilles tendon.

Methodology. Based on the Central Vivarium of the First Moscow State Medical University named after I.M. Sechenov (Sechenov University) conducted an experimental study on laboratory animals (rabbits) (n = 12) to create a wound surface in the oral cavity (limited vestibuloplasty according to Clark on the upper jaw) and its closure with collagen membranes with an assessment of the course of the postoperative period and subsequent histological examination of biomaterials: 1st – using a personalized collagen membrane, 2nd – using a collagen membrane with lactoferrin, 3rd – using a Mucograft membrane, 4th group – control.

Results. In the postoperative period, on the 3rd day, moderate swelling, and hyperemia in the area of vestibuloplasty were noted in the oral cavity of rabbits: the least pronounced swelling was in animals in the 2nd group of operations (1.5 ± 0.5 points) (p = 0.001), hyperemia – in the 3rd group (1.7 ± 0.4 points) (p = 0.001). On the 5th day in the oral cavity of experimental animals, hyperemia of the mucous membrane of the oral vestibule in the 2nd group was 0.8 ± 0.4 points (p = 0.001), and in the 3rd group – 1.8 ± 0.4 points (p = 0.001). According to the histological research method, a significant difference was noted in the quantity and quality of the formed soft tissues in the area of application of collagen matrices compared to healing by secondary intention (p < 0.05). The results of histological examination showed in group 2 epithelization with acanthosis and proliferation of the basal layer.

Conclusion. The effectiveness of the developed collagen membranes from the Achilles tendon has been proven in eliminating extensive wound defects of the oral mucosa.
THE INFLUENCE OF EDDY CURRENTS ON PARAMETERS OF ANISOTROPIC UNIPOLAR THERMOELEMENT
Authors: Ashcheulov A. A. , Verenko O. S. , Derevianchuk M. Ya. , Lavreniuk D. O.
Published: February 2024

The purpose of this study is to evaluate the influence of eddy thermoelectric and electric currents and eddy heat flows with a laminar flow character on the value of transverse thermoEMF E⊥ and efficiency η of an anisotropic unipolar thermocouple. In the case of transverse thermoEMF of an anisotropic unipolar thermoelement, the assessment of such influence was carried out taking into account the eddy current caused by the anisotropy of the thermoEMF, and for the evaluation of the efficiency η – taking into account the eddy currents caused by the anisotropy of the coefficients of thermoEMF αi, electrical conductivity σik and thermal conductivity κik (i, k = 1..3). The research results showed that the influence of the studied current leads to a change in the value of the optimal angle of inclination γ between one of the selected crystallographic axes and the length a of the thermoelement and to some decrease in the value of the transverse thermoelectric power. Efficiency η under the action of eddy thermoelectric and electric currents and eddy heat flow is more significantly affected. Numerical analysis shows that in the case of using such a material as cadmium antimonide, the effect on the transverse thermoEMF is 36% (γ = 45⁰), and the effect on the efficiency is more significant.
YAROSLAV MYKHAYLOVYCH BILANCHYN (ON HIS 85TH BIRTHDAY)
Authors: Yavorska V. V. , Buianovskyi A. O. , Trigub V. I. , Krasiekha Ye. N. , Tortyk M. Yo. , Adobovska M. V.
Published: February 2024

In connection with the 85th anniversary of the birth of Yaroslav Mykhailovych Bilanchyn – famous soil scientist, geographer and educator, dean of the Faculty of Geology and Geography (1985–2007), head of the Department of Soil Science and Soil Geography (1994–2017), Head of the Department of Geography of Ukraine, Soil Science and Land Cadastre (2017–2020) of Odesa I. I. Mechnikov National University, pedagogue, mentor, teacher, general information about his life and creative path and contribution to the theory and practice of domestic soil science and geography is presented and geographical education.
Newton’s method and its visualization
Authors: Hryhoriev Yu.
Published: February 2024

Relevance of work. Mathematical modulation in various fields of science and technology often leads to nonlinear equations or systems of such equations. Far from always, these equations can be solved by exact methods. More often it is necessary to use approximate methods. One of the most popular of them is Newton's method. In modern works, Newton's method often serves as the basis for the development of new approximate methods that accelerate the convergence of iterative processes or are used to solve systems of large orders.
The goal of the work. Visualize the work of the algorithm for solving the equation, as well as the system of equations according to Newton's method, so that the results of this work could be used when compiling electronic textbooks on the study of this method. Another goal is to study the method in the case when the system has several solutions; to study the possibility of using the method for equations with an infinite number of solutions.
Necessary existence conditions of Pω(Y0, Y1, λ0)-solutions of second-order differential equation with rapidly varying nonliniarity
Authors: Kusik L. I.
Published: February 2024

We consider a differential equation of the second order of the general form y’’ = f(t, y, y’), where f : [a, ω] x ΔY0 x ΔY1 → R – a continuous function, −∞ < a < ω ≤ +∞, ΔYi – one-side neighborhood of Yi, Yi ∈ {0, ±∞} (i ∈ {0, 1}). Under certain conditions for the function f, this equation can be represented close to the two-term differential equation, namely y’’ = α0p(t)ϕ1(y’)(1 + o(1)) at t↑ω, where ϕ1 is a rapidly varying function at y’ → Y1. Found the necessary conditions for the existence of solutions for which limt↑ω y(i) (t) + Yi (i ∈ {0,1}), limt↑ω [y’(t)]2/y(t)y’’(t) = λ0, so called Pω(Y0, Y1, λ0)-solutions. This type of solution was previously presented in works by Evtukhov V. M., Belozerova M. O. when studying the two-term equation y’’ = α0p(t)ϕ0(y)ϕ1(y’), where α0 ∈ {−1, 1}, p : [a, ω[→]0, +∞[–continuous function, ϕi : ΔYi →]0, +∞[(i = 0, 1)–continuous regularly variables for z → Yi (i = 0, 1) functions of orders σi (i = 0, 1), and σ0 + σ1 ≠ 1. Further, in the studies of V. M. Evtukhov, A. G. Chernikova for equation y’’ = α0p(t)ϕ0(y) necessary and sufficient conditions are established existence, as well as asymptotic at t↑ω representations Pω(Y0, Y1, λ0)-solutions in the case when ϕ0 is a rapidly varying function at y → Y0.
Evaluating Ecological Suitability and Carrying Capacity for Budo's Mangrove Ecosystem: Unveiling Ecotourism Potential and Limits
Authors: Oroh Dannie , Kontu Tommy , Lintong Oktavianus
Published: February 2024

Budo Village in North Sulawesi stands out as one of the top 50 recipients of the prestigious 2022 Indonesian Tourism Village Award. Notably, Budo is a popular tourist destination with a thriving mangrove area on Minahasa's northern peninsula. The Budo mangrove area has been designated as a tourist attraction since 1994 and garnered increased recognition in 2017, thanks to active promotional efforts aimed at coastal tourist destinations. Surprisingly, despite its transformation into a tourist destination, research has yet to be undertaken to assess the ecological suitability of mangroves in this context or determine the carrying capacity of the mangrove area. This study seeks to delve into the ecological suitability of Budo's mangrove ecological resources and investigate the carrying capacity of the area as a tourist destination. The results of this analysis categorize the Budo mangrove tourist destination as 'unsuitable,' as indicated by an IKW score of 1.5. Consequently, a comprehensive restoration approach is required to render this mangrove area suitable and viable for tourism. Mangrove restoration initiatives, coupled with more stringent adherence to ecotourism principles in the Budo mangrove area, along with considerations for its carrying capacity, could serve as vital steps towards achieving this objective.
The Human Right to an Environment Safe for Life and Health: Legal Regulation, Contemporary Challenges and Comparative Perspectives
Authors: Leheza Yevhen , Sinkevych Olena , Kravtsova Zorina , Kudriavtseva Olena , Cherniak Ievgeniia
Published: February 2024

Abstract: The purpose of the research is to disclose human rights to an environment safe for life and health.  Main content. The article reveals relationship between the concepts of “human rights” and "citizen’s rights” in the environmental sphere, “ecological rights”, “ecological responsibilities” and “the human right to an environment safe for life and health”. The war initiated by Russia caused significant damage to the environment, social and industrial infrastructure, flora and fauna.  Methodology:  The methodological basis of the research is the dialectical method of scientific knowledge, through the application of this method considered were legal, functional, organizational and procedural aspects of the essence of human rights to an environment safe for life and health. Conclusions. The legal grounds for the allocation of ecological rights to a separate institution in the system of constitutional rights are singled out, and their definition is derived. It was emphasized that Ukrainian citizens and non-governmental organizations made a lot of efforts to document the damages. In particular, EcoAction and Environment People Law organizations collect and publish relevant data on an ongoing basis. Thus, the "EcoZagroza" platform regularly publishes estimates of damages caused by environmental crimes, these estimates are calculated by the State Environmental Inspectorate of Ukraine.

Key words: human right, constitutional law, environmental conservation, environmental legislation, law.
Safeguarding Minors' Personal Data: Legal Principles in Information Security in Ukraine and Eurupean
Authors: Kobko Yevhen , Foros Hanna , Shperun Khrystyna , Nikitinskyi Oleksandr , Savchuk Roman
Published: February 2024

The research aims to uncover the legal regulations pertaining to the protection of minors' personal data, considered a crucial component of informational security. Through an analysis of Ukrainian and European legislation, in conjunction with the General Data Protection Regulation and the California Consumer Privacy Act, this study seeks to explore preventive measures against third-party abuse of children's information. The research highlights the responsibilities imposed on state authorities and legal entities, based on Ukrainian and European legislation, to safeguard personal data. The methodology employed in this article involves the utilization of both general scientific and specialized methods of scientific cognition. The specificity of the research subject, along with its purpose and tasks, guided the selection of these methods. The research results reveal various problematic issues related to the collection, storage, use, and distribution of personal data of minors. The obligation to protect an individual's rights to the processing and preservation of personal data or private information is a responsibility placed on state authorities in accordance with the legislation of Ukraine and European countries (Germany, Switzerland, France, Italy, Norway, Great Britain), as well as on legal entities that own or store the specified personal data. In conclusion, the protection of personal data emerges as a fundamental right, integral to the broader rights of family and private life. The study also underscores the importance of international cooperation mechanisms in addressing this multifaceted issue.
Development of a prototype of a theranostic system based on silica nanoparticles with immobilized fluorescent dyes and VEGF targeting ligand.
Authors: Cheburkin Yu. V. , Shulmeister G. A. , Bondarenko A. B. , Chistyakova A. V. , Korolev D. V.
Published: February 2024

Background. Administration of certain drugs causes undesirable effects associated with the systemic effect of the active substance on the entire body. Selective targeting of the drug to the affected tissue promotes a selective increase in the concentration of the substance in the area of interest, thereby reducing the systemic effect and enhancing the local therapeutic effect.

Objective. Development of a targeted delivery system for theranostic agents using recombinant human vascular endothelial growth factor type A (rhVEGF-A121) as a targeting ligand.

Design and method. To create the theranostic complex, commercially available reagents were used: the recombinant protein rhVEGF-A121 (cat.#: PSG140-10, LLC CyStorLab, Skolkovo, Russia) and fumed silica Aerosil (A-200, Degussa AG, Germany). The tosyl spacer that interconnects both components was synthesized in the laboratory. Protein conjugation with fluorophores was also carried out in-house. Indocyanine green (ICG; Sigma-Aldrich, USA) and rhodamine B (JSC Lenreaktiv, St. Petersburg, Russia) were taken for immobilization.

Results. In the course of the work, functionalization of silica nanoparticles (SiNPs) with a tosyl spacer was carried out, conjugates of SiNPs with rhVEGF-A121 were synthesized, and theranostic constructs based on SiNPs were obtained, including rhVEGF-A121 as a targeting ligand, and ICG/Rhodamine B as a visualizing label.

Conclusion. In the presented study, a prototype of a complex for targeted delivery of a theranostic agent to tissues with an active angiogenesis process, for example, to tumor and ischemic tissues, was developed. To solve the problem, we immobilized on the surface of SiNP a recombinant protein of human vascular endothelial growth factor (rhVEGF) to use as a guide ligand. Such a synthetic construct will help to deliver diagnostic and/ or medicinal substances packed in SiNP directly to cells that overexpress extracellular specific receptors of the VEGFR family. In subsequent in vivo experiments, delivery efficiency will be assessed by tissue accumulation of the fluorophores ICG and rhodamine B, which have been conjugated to the targeting ligand protein. The physicochemical characteristics of the obtained samples were studied by the methods of spectrophotometry and dynamic light scattering.
Ekonomiczna wycena otwartych przestrzeni miejskich i ich udział w jakości życia mieszkańców miast europejskich
Authors: Gruehn Dietwald
Published: February 2024

Jeśli chodzi o pierwotnie sformułowane pytanie można stwierdzić, że różne kryteria dotyczące zapewnienia otwartych przestrzeni mogą mieć wyraźne i znaczące zwiększenie wartości wpływu na ceny gruntów w Berlinie i Malmoe. Droższe ceny działek prywatnych w ramach „zielonych Środowisk” są wyrazem większego uznania dla ich mieszkańców. To odkrycie powinno być rozpoznawane przez polityków przy ustalaniu priorytetów w decyzjach finansowych i podatkowych. Władze lokalne powinny rozważyć, czy i w jaki sposób mogą pozyskiwać właścicieli nieruchomości w celu przyczynienia się do przyszłego finansowania na otwartej przestrzeni, czy systemu do tworzenia nowych parków lub na ich utrzymanie. Kwota powinna zależeć od zysków jakie właściciele nieruchomości uzyskują z atrakcyjnych terenów otwartych. Mogłoby to zostać wprowadzone poprzez modyfikacje stawek podatkowych. Procedura ta może stanowić jedno z możliwych „innowacyjnych podejść” finansowania otwartych przestrzeni. Wyniki te mogą także stanowić dane do dyskusji na temat malejącej liczby miast. Poza tymi czynnikami rozwoju i utrzymania wysokiej jakości otwartych przestrzeni mogą być one Środkiem do podniesienia jakości życia i wizerunku wszystkich tych miast, które „cierpią” na zmniejszającą się liczbę ludności i nie są w stanie konkurować z „mistrzami jakości życia”, takimi jak Wiedeń, Zurych czy Genewa.
Marketplace retail in Poland in the years 1995–2006
Authors: Klima Ewa , Zajączkowski Jarosław
Published: February 2024

In the late 80s and early 90s Poland witnessed a big boom of street trade. It was caused mainly by the transition into market economy and the liberation of the prices. At the same time the borders were opened which resulted in the increase of revenue in international trade and activated small entrepreneurs. Ever since the beginning, well-organized although not always legal, marketplaces became the competition for the „single table” street stalls. The marketplaces were usually located at city squares, local crossroads and sport stadiums.
PROBLEMATIKA MAHASANTRI DALAM TAHFIZ Al-QUR’AN (STUDI DI PONDOK PESANTREN ZIYADATUT TAQWA)
Authors: Ach. Shofwan  , Mansyuri Nur Indah
Published: February 2024

Untuk memelihara keauntentikan Al-Qur’an, pemeliharaannya diperlukan agar umat Islam tidak kehilangan arah. Salah satunya adalah dengan cara menghafal Al-Qur’an. Pendekatan kualitatif dengan jenis penelitian lapangan. Problematika Mahasantri dalam menghafal Al-Qur’an di Pondok Pesantren Ziyadatut Taqwa adalah sebagai berikut: pertama, Faktor ekternal meliputi lingkungan pertemanan dan smartphone. Kedua, Faktor Internal meliputi manajemen waktu, malas atau kurang sungguh-sungguh dalam menghafal Al-Qur’an, banyak pikiran dan mengontrol hawa nafsu. Solusi pemecahan problematika di Pondok Pesantren Ziyadatut Taqwa adalah sebagai berikut: pertama, Faktor ekternal meliputi menciptakan lingkungan yang baik pembatasan penggunaan smartphone dan buku absen. Kedua, Internal meliputi meningkatkan motivasi yang baik, manajemen waktu yang baik, dilakukan dengan sungguh-sungguh, pandai memilih teman dan mencari tempat yang nyaman.