bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembelajaran Bahasa Arab dengan Menggunakan E-Learning Berbasis Moodle
Authors: Aliyah Siti Alfi , Hidayanti Primasti Nur Yusrin
Published: August 2022

This study examines the use of Moodle-Based E-Learning in Arabic Learning. The purpose of this study is to define and explain how Moodle-based e-learning can be used in learning Arabic. An analytical descriptive strategy based on a literature review was used as a research method. According to research findings, many students feel bored during the Arabic learning process, so it is necessary to make interesting and interactive media. One of the interesting uses of learning media in supporting education today is Moodle-based e-learning because Moodle has a number of unique and interesting features in supporting the learning process. Therefore, the use of moodle-based e-learning is very suitable for use in learning Arabic, given that currently the world of education cannot be separated from technology and internet networks, besides that there are many educational institutions that have been facilitated by infrastructure in utilizing existing technology.
Religious Bourgeois Lifestyle of Celebrity Hijrah: Reading the Resurrection of the Muslim Middle Class Based on Cultural Imperalism and Global Economic Factors
Authors: Sunaryanto Sunaryanto , Rizal Sofyan , Zulkifli Zulkifli
Published: August 2022

This paper attempts to analyze the bourgeois religious lifestyle of celebrities' hijrah from the perspective of globalization by focusing on how imperialism influences this lifestyle and why it is in line with the global economy. The theory used is the globalization theory of Gill Branston and Roy Stafford. The qualitative research approach is based on online and printed literature from books, websites, journals, and relevant research results. After the data is collected, the data analysis uses the interactive model of Miles and Huberman, namely data reduction, data display, interpretation, and conclusion. This study concludes that a bourgeois religious lifestyle is a form of Islamic identity for hijrah celebrities. The lifestyle displayed is bourgeois but does not leave Islam a symbol of Piety. The interpretation of the hijrah celebrity towards globalization is to construct it as a religious bourgeois identity. Cultural imperialism is a factor in forming the religious bourgeois lifestyle of celebrities who migrate in the identity displayed in the public space outside the network and in the public space in the network. The bourgeois religious lifestyle of hijrah celebrities can be in line with the interests of the global economy because they both need and complement each other.
The Influence of The Human Development Index, Unemployment Rate, and Illiteracy Population on Poverty Level in Indonesia for the Period 2015-2020
Authors: Ipmawan Hasan , Kristanto Dwi , Hendrawan Koen , Kuncoro Aris Wahyu
Published: August 2022

Unemployment and poverty are issues that require serious and systematic solutions. So far, the human development index, unemployment rate, and illiteracy rate have dominated. This study looks into how the Human Development Index affects poverty in Indonesia. Second, examine the impact of Unemployment on poverty in Indonesia. Third, examine the impact of Illiteracy on poverty in Indonesia. The Stepwise technique was chosen in this study because it provides information on the independent variables that influence the dependent variable. The Human Development Index, Education Level, and Illiteracy Population were studied sequentially. This study employed secondary data. The statistics were gathered from third sources and are available at the Central Statistics Agency (BPS). The research shows that the three variables are directly associated with poverty in Indonesia. Less effective programs tend to be partial. So, as a policymaker, the government must start an integrated program focusing on the three points mentioned.
Contribution of Learning Method and Activities to the Learning Outcomes of Fikih Students at Madrasah Tsanawiyah
Authors: Zega Faris Indra Pratama , Nahar Syamsu , OK Azizah Hanum
Published: August 2022

The purpose of this study is to determine the impact of learning methods and learning activities on the learning outcomes of fiqh students at a private madrasah tsanawiyah in Gunung Sitoli city. This Research quantitative research method with a correlation research approach was used in this study. This study employs both a population and a sample. This study included four madrasas as participants. Only 72 students from the four madrasahs are included in the population. The sample is comprised of 72 students drawn from the entire population. The study's findings indicate that there is a positive and significant relationship between the application of learning methods and student learning outcomes of Fiqh, which means that the higher and more positive the application of learning methods, the higher and more positive the student learning outcomes, with an effective contribution of 9.90 percent. This means that a variation of 9.90% in the variable application of learning methods can be predicted in terms of improving students' Fiqh learning outcomes.
The Effectiveness of Learning Interest and Communication Ability on Fikih Learning Outcomes of Students Madrasah Ibtidaiyah Negeri
Authors: Zalukhu Sapran , Arsyad Junaidi , Hanum OK Azizah
Published: August 2022

Students who are enthusiastic about learning will find it easier to comprehend and apply fiqh teaching material. The enthusiasm of students for independent learning and discovering new information in Fiqh is an indicator. Because there is an attraction for him, students who are interested in a lesson will study it thoroughly. Lessons that are interesting to students are easily remembered. When accompanied by interest, the learning process will run smoothly. This is a quantitative study using the correlational research method, to describe three things: determining the effect of the variable interest in learning (X1) on the variable learning outcomes of Fiqh (Y) students of Madrasah Ibtidaiyah Negeri Nias Utara and looking at the effect of the variable ability to communicate (X2) on the variable learning outcomes of Fiqh (Y) students of Madrasah Ibtidaiyah The study's findings indicate a shared interest in learning and communication skills with the learning outcomes of Fiqh students at Madrasah Ibtidaiyah Negeri Nias Utara. The higher and more positive the students' interest in learning and ability to communicate, the higher and more positive the Fiqh learning outcomes for Madrasah Ibtidaiyah Negeri Nias Utara students, with an effective contribution of 71.4 percent.
Pengembangan Lembar Kerja Siswa (LKS) pada Mata Pelajaran Matematika Materi Pecahan Kelas IV Sekolah Dasar
Authors: Nurmawati Sri , Ain Siti Quratul
Published: August 2022

This development research was carried out based on the teacher's difficulty in presenting interesting student worksheets (LKS), this is evidenced by the incompleteness and interestingness of other teaching materials such as worksheets that can help students understand the material. This study aims to test the feasibility of LKS in mathematics subjects with the content of fractions in fourth-grade elementary school. This research is development research using the ADDIE model. The data collected in this study are quantitative data and qualitative data. The methods used to collect data are observation, interviews, and questionnaires. The subjects involved in this study were 1 design expert, 1 material expert and 1 linguist, 1 teacher, and 6 students. The data analysis technique used is quantitative and qualitative descriptive data analysis techniques. The results showed that the feasibility of the LKS from the aspects of design, material, and language obtained an average score of 93.13% by category. Then the analysis of the fourth-grade teacher's response questionnaire to the LKS obtained an average of 86.91% with the "Very Interesting" category while the analysis of the student response questionnaire obtained an average of 100% with the "Very Interesting" category.
The Traditionalism of the Islamic Boarding School Education System in the Era of Modernization
Authors: Arifin M. Zainal
Published: August 2022

In a system, education cannot be separated from the various life systems that surround it. The education system must always metamorphose towards a more ideal level. In the modern era, it is assumed that traditional Islamic boarding schools will experience changes, but the problem is when carrying out changes (modernization) do salafiyyah Islamic boarding schools leave their traditions? This study aims to find out how the policy of the Islamic boarding school will be carried out when there is a need to maintain its traditions and the desire for modernization? This is because the connotations between tradition and modernization are two camps that are difficult to unite. Answering these questions, the Assya`roniyyah Islamic Boarding School is used as a material for discussion, using qualitative descriptive methods and historical sociological and phenomenological approaches the author tries to analyze the education system that is run. The results of the research show that the education system of the Assya`roniyyah Islamic Boarding School is a combination of elements of traditionalism and modernization. The renewal of the salafiyyah Islamic boarding school education system on the one hand is a linear process, meaning that the elements of the education system have been updated in response to modernity, but on the other hand, there is a necessity to stick to the traditional paradigm. So, in essence, the changes that occur in the boarding school system are a process of changing the creation of integral education.
Transformation of The Education System in Islamic Educational Dormitory
Authors: Haryanto Sri , Ngarifin Ngarifin
Published: August 2022

: This study aims to explain the transformation of the education system in the Tegalrejo Islamic College Dormitory, Magelang, Central Java. Change of education in Islamic college dormitories requires various kinds of knowledge and skills that support the observation, recording, management, and description of the facts on the phenomena that occur in the field have scientific power. For this reason, this study uses two approaches, namely socio-anthropological and phenomenological. Observation, in-depth interviews, and documentation studies, data collection techniques were carried out. The collected data is then organized, interpreted, and critically analyzed through case analysis and cross-case analysis. Thus to compile the concept and abstraction of research findings. The results showed that there had been a transformation of the education system at the Tegalrejo Islamic College Dormitory in Magelang as evidenced by changes in the institutional management side; pesantren curriculum; educational methods; educational goals.
Athletic Monitoring in Basketball: A Qualitative Exploratory Approach
Authors: Serrano Brian , Comer Matt , Puls Geoffrey
Published: August 2022

The competitiveness of sport continues to increase with the corollary increase in sport technology. Sport technology is an umbrella that encompasses biometrics, wearable technology, and data analytics. Central to sport technology is a close relative, sport analytics. If sport technology is the general term for measuring what the athlete is experiencing from a performance standpoint, then sport analytics is the process of cleaning, processing, and manipulating these variables into meaningful output. The number of variables that can be collected are extensive but can be generally categorized into internal and external metrics. Internal metrics seek to measure how the athlete responds to training load (HR, HRV, Hormones, Sleep patterns). External metrics seek to measure how much work the athlete is performing (Live player tracking, Countermovement Jump, Isometric Mid-Thigh Pull). Internal and external metrics are continually evolving in the manner they are collected which depends on the time, resources, and staff allocation of an organization. This is where the collaboration between sport scientists and sport performance staff can come together to overlay variables and find relationships. There is no correct way to analyze data because each organization will have their own goals. For example, data could be used for injury mitigation, readiness assessment, or simply to establish baseline values. Some common statistical techniques that can be used include correlation, regression, and principal component analysis (PCA). However, performing these calculations may be complex and some organizations may lack a practitioner which can limit their ability to use data. In seeing this gap, the authors propose a qualitative approach to workload monitoring made for basketball but can be applied to most sports. The purpose of this paper is to empower sports performance staffs to learn and implement the basics of qualitative athletic monitoring approach.
Kualitas Pelayanan Administrasi Kependudukan di Masa Pandemi Covid-19 di Kabupaten Lumajang
Authors: Sholihah Millatus
Published: August 2022

Penelitian ini bertujuan untuk mengetahui kualitas pelayanan administrasi kependudukan dimasa covid-19 di Kabupaten Lumajang. Penelitian ini menggunakan paradigma kualitatif  yang bersifat deskriptif dengan menggunakan sumber-sumber data yang berasal dari jurnal ilmiah, buku, situs web resmi yang kemudian digambarkan dalam sebuah analisis untuk menggambarkan kualitas pelayanan administrasi kependudukan dimasa pandemi covid-19 di Kabupaten Lumajang. Hasil penelitian menunjukkan bahwa pada masa pandemi covid-19 terdapat beberapa inovasi pelayanan administrasi kependudukan di Kabupaten Lumajang yang berbasis pada peningkatan kualitas pelayanan terhadap masyarakat.
Analisis Sentimen Masyarakat Terhadap Kebijakan Vaksinasi Covid-19 pada Media Sosial Twitter menggunakan Metode Logistic Regression
Authors: Ash Shiddicky  , Surya Agustian
Published: August 2022

Kebijakan melakukan vaksinasi ini hadir sebagai upaya pemerintah dalam merespon wabah penyakit menular Covid-19, tentu dalam suatu kebijakan tidak terlepas dari dukungan maupun kontra. Berbagai komentar ini muncul dari masyarakat baik berupa opini atau fakta pengalaman yang mereka alami, ratusan bahkan ribuan komentar ini dapat menjadi data yang berharga untuk dijadikan bahan analisis dan mengetahui reaksi masyarakat ketika kebijakan vaksinasi Covid-19 ini diterapkan ke masyarakat, data komentar ini dapat diproses untuk mendapatkan informasi, salah satu analisis pendapat atau review dapat dilakukan adalah menggunakan analisis sentimen. Berdasarkan uraian diatas, dapat memanfaatkan pembelajaran mesin menggunakan algoritma Logistic Regression untuk membantu dalam mengolah data informasi tersebut, dalam hal ini klasifikasi. Hasil pengujian menunjukan tingkat akurasi mencapai 82% terhadap data dev akan tetapi tidak diikuti oleh nilai F1-Score yang cukup baik untuk membangun sebuah model, hal ini disebabkan oleh data train memiliki distribusi klasifikasi yang tak seimbang. Maka dilakukan proses Slicing data serta Tuning Hyperparameters yang bertujuan untuk mendapatkan model terbaik, setelah menerapkan model terbaik yang didapat dari data dev maka dilakukan pengujian terhadap data test, metode Logistic Regression menghasilkan nilai akurasi 67% dan F1-score 60% terhadap data test hasil ini membuktikan bahwa model yang dibangun cukup handal dalam melakukan klasifkasi, terbukti nilai f1-score dan akurasi cukup berimbang dan lebih baik dari Naïve Bayes, SVM dan LSTM.
Development and Validation of HPLC Method for the estimation of Triamcinolone Acetonide and 5-Fluorouracil
Authors:   s, Diksha Gulati
Published: August 2022

A sensitive HPLC method has been developed and validated for the determination of Triamcinolone Acetonide and 5-Fluorouracil in topical formulations. The developed method is found to be specific, reproducible and stability indicating. The Phenomenex C18, 250 × 4.6 mm, 5µm particle size column was used and mobile phase contains two solvents: Solvent A contains 10mM phosphate buffer pH 3.0 and solvent B was Acetonitrile. The detector linearity was established from concentrations ranging from 1 μg/ml to 10 μg/ml for both Triamcinolone Acetonide and 5-Fluorouracil with a correlation coefficient of 0.999. The limit of detection(LOD) and limit of quantification(LOQ) for Triamcinolone Acetonide was found to be 0.04 and 0.13 respectively and 5-Fluorouracil was found to be 0.01 and 0.03 respectively. The method was proved to be robust with respect to changes in flow rate, column temperature, mobile phase ratio and detector wavelength. Keywords: Triamcinolone Acetonide, 5-fluorouracil, Validation, HPLC method, topical formulations
Potential of Underground Hydrogen Storage in Oman
Authors: Nasser Mohammed Al Rizeiqi  , Nasser Al Rizeiqi  , Ali Nabavi
Published: August 2022

Hydrogen can provide a viable source of energy that can covers the world’s energy requirement in the next coming years. One of the major keys to wholly develop hydrogen energy is to provide a safe, cost efficient and compacted type of hydrogen storage. Geological reserves are considered a suitable space for hydrogen storage. In this research, we are trying to examine if there was any technical potential for hydrogen storage based on Oman’s geology by Identifying geological deposit in Oman that can be used for hydrogen storage and analyzing salt deposits for hydrogen storage suitability. By overviewing the possible underground hydrogen methods and based on Oman’s geology, deep aquifers were not suitable for hydrogen storage; due to the lack of large sedimentary basin, no experience for similar projects and the risks associated with surrounding environment. Depleted reservoir needs more study for deployment; there are no experiences of such projects for UHS. Salt basins are good candidate for underground storage; due to the large salt basin in Oman, salt caverns are known to successfully contain hydrogen and the guaranteed safety of the storage. Analysing the technical potential salt deposits was based on a good depth dome, salt thickness and salt dome size. The main findings illustrate that, two salt domes (Qarn Shamah and Qarn Alam) were offering a good potential of estimated working gas volume of hydrogen around 90 m3 hydrogen (0.2 TWh). Nevertheless, more future work is needed to confirm the geotechnical feasibility of salt domes in terms of internal complex structure, chemical composition and purity of salt.
ASSISTÊNCIA INTEGRAL À SAÚDE E A INCUMBÊNCIA DO ENFERMEIRO NA ATENÇÃO PRIMÁRIA
Authors: Rocha de Souza Bruno
Published: August 2022

Objetivou-se compreender a integralidade do cuidado baseando no princípio doutrinário do sistema único de saúde brasileiro e compreender o papel da enfermagem, dando ênfase ao profissional enfermeiro na prestação do cuidado integral a população na atenção primaria de saúde brasileiro, sendo realizada revisão bibliográfica, de caráter exploratório e descritivo, pelo método qualitativo, baseados em artigos científicos e estudos bibliográficos, sem recorte temporal, no idioma português, pesquisadas nas bases de dados LILACS, BDENF-enfermagem, Google acadêmico, SciELO e periódicos da CAPES. Conclui-se que ao profissionalenfermeiro cabe à gestão, planejamento, participação em programas de saúde e vigilância, além de educação e consultas de enfermagem. O processo da integralidade se torna um grande desafio para todas as esferas do governo, diante do contexto dosistema único de saúde, pois é necessária uma grande reestruturação do sistema de saúde, incluindo a melhoria a acessibilidade da assistência de saúde nos seus diversos níveis de complexidade.
HEART AND VESSEL REMODELING IN DIFFERENT AGE GROUPS OF PATIENTS WITH ARTERIAL HYPERTENSION
Authors: Kandilova V. N.
Published: August 2022

Actuality. It is known that each of the factors (arterial hypertension (AH) and age) has a negative effect on the remodeling of both the heart and vessels, while their combined effect has not been sufficiently studied. 

The aim. Assessment of manifestations of cardiac and vascular remodeling (by the example of common carotid arteries (СCA) and vasomotor endothelium function (right brachial artery)) in patients with AH degree I-III in different age groups.

Material and methods. The study involved 124 (86 men and 38 women) patients at the age from 27 to 81 years (average age of patients 55.7+1.01 years) with AH degree I-III. The presence and variant of myocardial remodeling with calculation of criteria of left ventricular hypertrophy (LVH), myocardial mass (MM) and MM index (MMI) of LV by indexation to the patient’s body surface area were studied in all patients by means of echocardiographic investigation (EchoCG) using the Vivid S5 3Sc-RS echocardiograph with a multifrequency sensor 2.0-3.5 MHz. Normal values of MM were considered to be 67-162 grams (g) for women and 88-224 for men, and MMI - not more than 95 and 115 g/m2, respectively. Types of LVH were determined according to recommendations of Pugliese N.R. et al. (2017), being subdivided into concentric (C) and eccentric (E) LVH. Ultrasound scanning was used to investigate CCA on both sides. The results of reactive hyperemia test on the right brachial artery and blood lipid profile were studied with the calculation of atherogenicity coefficient (AC). The data analysis was carried out with the help of Statistica 12 application package with determination of mean values (M), minimum, maximum and mean error (m), median and interquartile range for the CCA intima-media thickness (IMT). The Spearman rank correlation coefficient (r) was used to estimate the relationship between these variables. The significance level of all statistical tests was accepted at p˂0.05.

The results of the study confirmed the presence of cardiac and vascular remodeling in patients with AH of different degrees with the tendency to increase in older age groups. The CCA remodeling parameter values were also significantly higher in the groups of middle-aged and elderly persons, some of which also had atherosclerotic plaques (AP). The number of patients with disturbed endothelial vasomotor function also somewhat increased with age.

Conclusion. Thus, the age of the examined patients with AH had a significant influence on aggravation of the heart and vessel remodeling processes and increasing frequency of endothelial dysfunction development
OGLE-2017-BLG-1038: A Possible Brown-dwarf Binary Revealed by Spitzer Microlensing Parallax
Authors: Malpas Amber , Albrow Michael D. , Yee Jennifer C. , Gould Andrew , Udalski Andrzej , Martin Antonio Herrera , Beichman Charles A. , Bryden Geoffery , Novati Sebastiano Calchi , Carey Sean , Henderson Calen B. , Gaudi B. Scott , Shvartzvald Yossi , Zhu Wei ,   Spitzer team, Cha Sang-Mok , Chung Sun-Ju , Han Cheongho , Hwang Kyu-Ha , Jung Youn Kil , Kim Dong-Jin , Kim Hyoun-Woo , Kim Seung-Lee , Lee Chung-Uk , Lee Dong-Joo , Lee Yongseok , Park Byeong-Gon , Pogge Richard W. , Ryu Yoon-Hyun , Shin In-Gu , Zang Weicheng ,   KMTNet Collaboration, Iwanek Patryk , Kozłowski Szymon , Mróz Przemek , Pietrukowicz Paweł , Poleski Radoslaw , Rybicki Krzysztof A. , Skowron Jan , Soszyński Igor , Szymański Michał K. , Ulaczyk Krzysztof ,   OGLE Collaboration
Published: August 2022

We report the analysis of microlensing event OGLE-2017-BLG-1038, observed by the Optical Gravitational Lensing Experiment, Korean Microlensing Telescope Network, and Spitzer telescopes. The event is caused by a giant source star in the Galactic Bulge passing over a large resonant binary-lens caustic. The availability of space-based data allows the full set of physical parameters to be calculated. However, there exists an eightfold degeneracy in the parallax measurement. The four best solutions correspond to very-low-mass binaries near (

M

1

=

170

−
50

+
40

M

J

and

M

2

=

110

−
30

+
20

M

J

), or well below (

M

1

=

22.5

−
0.4

+
0.7

M

J

and

M

2

=

13.3

−
0.3

+
0.4

M

J

) the boundary between stars and brown dwarfs. A conventional analysis, with scaled uncertainties for Spitzer data, implies a very-low-mass brown-dwarf binary lens at a distance of 2 kpc. Compensating for systematic Spitzer errors using a Gaussian process model suggests that a higher mass M-dwarf binary at 6 kpc is equally likely. A Bayesian comparison based on a galactic model favors the larger-mass solutions. We demonstrate how this degeneracy can be resolved within the next 10 years through infrared adaptive-optics imaging with a 40 m class telescope.
X-Raying the Birth of Binary Neutron Stars and Neutron Star–Black Hole Binaries
Authors: Kashiyama Kazumi , Sawada Ryo , Suwa Yudai
Published: August 2022

We consider fallback accretion after an ultrastripped supernova (USSN) that accompanies formation of a binary neutron star (BNS) or a neutron star–black hole binary (NS–BH). The fallback matter initially accretes directly to the nascent NS, while it starts to accrete to the circumbinary disk, typically 0.1–1 day after the onset of the USSN explosion. The circumbinary disk mass further accretes, forming mini disks around each compact object, with a super-Eddington rate up to a few years. We show that such a system constitutes a binary ultraluminous X-ray source, and a fraction of the X-rays can emerge through the USSN ejecta. We encourage follow-up observations of USSNe within ≲100 Mpc and ∼100–1000 days after the explosion using Chandra, XMM Newton, and NuSTAR, which could detect the X-ray counterpart with time variations representing the properties of the nascent compact binary, e.g., the orbital motion of the binary, the spin of the NS, and/or the quasiperiodic oscillation of the mini disks.
Single Pulse Dispersion Measure of the Crab Pulsar
Authors: Lewandowska N. , Demorest P. B. , McLaughlin M. A. , Kilian P. , Hankins T. H.
Published: August 2022

We investigate the use of bright single pulses from the Crab pulsar to determine separately the dispersion measure (DM) for the Main Pulse and Interpulse components. We develop two approaches using cross-correlation functions (CCFs). The first method computes the CCF of the total intensity of each of the 64 frequency channels with a reference channel and converts the time lag of maximum correlation into a DM. The second method separately computes the CCF between every pair of channels for each individual bright pulse and extracts an average DM from the distribution of all channel-pair DMs. Both methods allow the determination of the DM with a relative uncertainty of better than 10−5 and provide robust estimates for the uncertainty of the best-fit value. We find differences in DM between the Main Pulse, the Low Frequency Interpulse, and the High Frequency Interpulse using both methods in a frequency range from 4 to 6 GHz. Earlier observations of the High Frequency Interpulse carried out by Hankins et al. (2016) resulted in DMHFIP–DMMP of 0.010 ± 0.016 pc cm−3. Our results indicate a DMHFIP–DMMP of 0.0127 ± 0.0011 pc cm−3 (with DMcomp being the DM value of the respective emission component), confirming earlier results with an independent method. During our studies we also find a relation between the brightness of single pulses in the High Frequency Interpulse and their DM. We also discuss the application of the developed methods on the identification of substructures in the case of Fast Radio Bursts.
Measurements of the Hubble Constant with a Two-rung Distance Ladder: Two Out of Three Ain’t Bad
Authors: Kenworthy W. D’Arcy , Riess Adam G. , Scolnic Daniel , Yuan Wenlong , Luis Bernal José , Brout Dillon , Casertano Stefano , Jones David O. , Macri Lucas , Peterson Erik R.
Published: August 2022

The three-rung distance ladder, which calibrates Type Ia supernovae (SNe Ia) through stellar distances linked to geometric measurements, provides the highest precision direct measurement of the Hubble constant. In light of the Hubble tension, it is important to test the individual components of the distance ladder. For this purpose, we report a measurement of the Hubble constant from 35 extragalactic Cepheid hosts measured by the SH0ES team, using their distances and redshifts at cz ≤ 3300 km s−1, instead of any more distant SNe Ia, to measure the Hubble flow. The Cepheid distances are calibrated geometrically in the Milky Way, NGC 4258, and the Large Magellanic Cloud. Peculiar velocities are a significant source of systematic uncertainty at z ∼ 0.01, and we present a formalism for both mitigating and quantifying their effects, making use of external reconstructions of the density and velocity fields in the nearby universe. We identify a significant source of uncertainty originating from different assumptions about the selection criteria of this sample, whether distance or redshift limited, as it was assembled over three decades. Modeling these assumptions yields central values ranging from H
0 = 71.7 to 76.4 km s−1 Mpc−1. Combining the four best-fitting selection models yields

H

0

=

72.9

−
2.2

+
2.4

as a fiducial result, at 2.4σ tension with Planck. While SNe Ia are essential for a precise measurement of H
0, unknown systematics in these supernovae are unlikely to be the source of the Hubble tension.
Electron-scale Magnetic Peaks Upstream of Mercury’s Bow Shock: MESSENGER Observations
Authors: Chen Y. Q. , Wang G. Q. , Wu M. Y. , Xiao S. D. , Zhang T. L.
Published: August 2022

Electron-scale magnetic peaks (ESMPs) with spatial sizes less than one local ion gyroradius have been recently revealed to exist in the terrestrial magnetosheath and solar wind at 1 au. Whether they widely exist in the astrophysical plasma is unclear. Here, we investigate the magnetic peaks with a period of 0.1–100 s upstream of Mercury’s bow shock by using the magnetic field data from the MESSENGER spacecraft. Based on the distribution of their durations, these magnetic peaks can be divided into two groups: one with durations less than 0.6 s and the other with durations larger than 0.6 s. The durations in each group obey a log-normal distribution. The magnetic peaks with durations less than 0.6 s are inferred to be electron scale, suggesting that ESMPs exist in the solar wind at Mercury’s orbit. The median duration of these ESMPs is ∼0.3 s. The ESMPs have a larger occurrence rate near the bow shock and prefer to occur when the ambient interplanetary magnetic field (IMF) can be connected to the bow shock, which suggests that the foreshock could be one source region of these ESMPs. Their occurrence rate also tends to be larger when the IMF strength is weaker. Our observations also suggest that some ESMPs originate from the upstream solar wind. The properties of the ESMPs found here could help to shed light on their generation mechanisms and their roles in the astrophysical plasma.
An Overdensity of Red Galaxies around the Hyperluminous Dust-obscured Quasar W1835+4355 at z = 2.3
Authors: Luo Yibin , Fan Lulu , Zou Hu , Shen Lu , Lin Zesen , Hu Weida , Lin Zheyu , Tao Bojun , Chen Guangwen
Published: August 2022

Wide-field Infrared Survey Explorer all-sky survey has discovered a new population of hot dust-obscured galaxies (Hot DOGs), which have been confirmed to be dusty quasars. Previous statistical studies have found significant overdensities of submillimeter and mid-IR-selected galaxies around Hot DOGs, indicating they may reside in dense regions. Here we present the near-infrared (J and K

s
bands) observations over a

7
.′
5
×
7
.′
5

field centered on a Hot DOG W1835+4355 at z ∼ 2.3 using the wide-field infrared camera on the Palomar 200 inch telescope. We use the color criterion J − K

s
> 2.3 for objects with

K
S

<
20

, to select distant red galaxies (DRGs). We find a significant excess of number density of DRGs in the W1835+4355 field compared to three control fields, by a factor of about two. The overdensity of red galaxies around W1835+4355 is consistent with the multiwavelength environment of Hot DOGs, suggesting that Hot DOGs may be a good tracer for dense regions at high redshift. We find that W1835+4355 does not reside in the densest region of the dense environment traced by itself. A possible scenario is that W1835+4355 is undergoing a merging process, which lowers the local number density of galaxies in its surrounding region.
Evidence for a Dense, Inhomogeneous Circumstellar Medium in the Type Ia SNR 0519-69.0
Authors: Williams Brian J. , Ghavamian Parviz , Seitenzahl Ivo R. , Reynolds Stephen P. , Borkowski Kazimierz J. , Petre Robert
Published: August 2022

We perform an expansion study of the Balmer-dominated outer shock of the SNR 0519−69.0 in the LMC by using a combination of new Hubble Space Telescope (HST) WFC3 imagery obtained in 2020 and archival ACS images from 2010 and 2011. Thanks to the very long time baseline, our proper motion measurements are of unprecedented accuracy. We find a wide range of shock velocities, with the fastest shocks averaging 5280 km s−1 and the slowest grouping of shocks averaging just 1670 km s−1. We compare the Hα images from HST with X-ray images from Chandra and mid-IR images from Spitzer, finding a clear anticorrelation between the brightness of the remnant in a particular location and the velocity of the blast wave at that location, supporting the idea that the bright knots of X-ray and IR emission result from an interaction with a dense inhomogeneous circumstellar medium. We find no evidence for X-ray emission, thermal or nonthermal, associated with the fastest shocks, as expected if the fastest velocities are the result of the blast wave encountering the lower density ambient medium of the LMC. We derive an age of the remnant of ≤670 ± 70 yr, consistent with results derived from previous investigations.
The Viability of Using Remote Controlled Mechanical Chest Compression Devices to Reduce Contamination in Cardiac Arrest Patients during the COVID-19 Pandemic
Authors: Apiratwarakul Korakot , Cheung Lap Woon , Bhudhisawasdi Vajarabhongsa , Tiamkao Somsak , Ienghong Kamonwon
Published: August 2022

BACKGROUND: Mechanical chest compression devices play an important role in assisting patients undergoing cardiac arrest. However, this equipment induces an aerosol-generating procedure that could contaminate hospital staff. The development of a remote control system for mechanical chest compression devices may solve the problem; however, there are currently no studies regarding the efficacy of this system.

AIM: This study aims to analyze efficacy of remote control systems for mechanical chest compression devices and compare it with non-remote control systems.

METHODS: This was an analytical cross-sectional study at Srinagarind Hospital, Thailand. Data were collected in two periods of the study. The first period was between January and December 2021 using a non-remote control system to operate the mechanical chest compression device. The second period was from January to April 2022 and collected data on the use of a remote control system.

RESULTS: Sixty-four participants were examined over the 16-month period of the study. A total of 53.1% (n = 34) of participants were male and the mean age of the patients was 52.4 ± 5.1 years old. The number of emergency medical service members (EMS) needed for resuscitation in the remote control group was less than the non-remote control group (3 vs. 5; p = 0.040). The number of emergency department (ED) members needed for resuscitation in the remote control group was four compared with eight in the non-remote control group.

CONCLUSIONS: The remote controlled mechanical chest compression device can effectively reduce the number of staff working both in the EMS and in the ED of the hospital, thus reducing exposure and contamination from aerosol-generating procedure. It was also proven accurate in terms of rate and depth of chest compression according to resuscitation guidelines.
The Analysis Quality of Service with Outpatient Satisfaction Participants of Social Security Administrator in Ge’tengan Public Health Center, Tana Toraja Regency
Authors: Arifin Muhammad Alwy , Palutturi Sukri , Abadi Muh. Yusri , Sudirman Sudirman , Mallongi Anwar
Published: August 2022

The quality of service is an effort to fulfill the needs accompaniing by the wishes of consumers and the accuracy of the way of delivery in order to meet the expectations and satisfaction of those customers. The quality of service is one of the things that relates to customer satisfaction in this case the patient. The next effect will continue in the process of forming an improved public health center image. This research aims to find out the relationship of service quality based on the dimensions of comfort, timeliness, information and affordability of access with the satisfaction of outpatient participants BPJS PBI in Ge'tengan Public Health Center Tana Toraja Regency. This type of research is quantitative research using cross-sectional study design. This type of research is quantitative research using cross-sectional study design. The population in this study was 10,445 people. Sampling using side accidental, obtained samples as many as 96 respondents. The instruments used in this study were questionnaires and then the data was processed using the Statistical Package for the Social Sciences SPSS program. As well as the analysis used is univariate analysis and bivariate analysis. The results of the study obtained variables related to the satisfaction of outpatient participants BPJS PBI in The Center for Public Health Ge'tengan Tana Toraja district is the dimension of comfort p = 0,000, punctuality p = 0,000, and information p = 0.048. While the variables that are not related to the satisfaction of outpatient participants BPJS PBI participants is the dimension of affordability of access p= 0.959.
The Biological Role of Advanced Glycation End Products in the Development and Progression of Colorectal Cancer
Authors: Dawood Muthear , Younus Zaid Muwafaq , Alnori Mohammed , Mahmood Sameer
Published: August 2022

“Colorectal cancer” (CRC) is one of the most prevalent cancers, posing a scientific challenge and serving as a model for investigating the molecular pathways underlying its development. “Advanced glycation end products” (AGEs) have drawn interest in this context. The buildup of these diverse, chemically complex groups, which are formed by a “non-enzymatic interaction” between reducing sugar and a range of macromolecules, significantly increases “inflammation and oxidative stress” in the body, which has long been associated to cancer formation. The traditional pathways that promote AGE formation, as well as the significance of AGEs’ interaction with the receptor for “advanced glycation end products” (RAGE) and other means involved in CRC initiation and progression, are discussed in this review.
Effects of fumarate on renal vascular reactivity and the modulation of blood pressure in normotensive rats: Possible contribution of the nitric oxide synthase-nitric oxide system
Authors: Edosuyi Osaze , Choi Myung , Igbe Ighodaro , Oyekan Adebayo
Published: August 2022

Introduction: Fumarate, the tricarboxylic acid (TCA) cycle intermediary, has been linked to nitric oxide (NO) produc­tion. NO plays a prominent role in the physiological regulation of blood pressure and renal hemodynamics. This study is aimed to investigate any contribution of fumarate to blood pressure and renal hemodynamics in normotensive rats with a possible link to the nitrergic system.

Materials and methods: Fumarate (1, 3 and 10 μmol) was injected into isolated perfused kidneys, pre-constricted with epinephrine (30 μM). The fumarase inhibitor, pyromellitic acid (PMA) (1, 3 and 10 μM), was used to perfuse the iso­lated kidney and perfusate was collected for nitric oxide and fumarate assays. An acute blood pressure study involved the injection of bolus doses of fumarate (0.1, 0.3 and 1 μg/kg, iv) or PMA (1, 3 and 10 μg/kg, iv) to normotensive rats in the presence of N(ω)-nitro-L-arginine methyl ester (L-NAME) (10 mg/kg, iv) or PMA (1, 3 and 10 μg/kg).

Results and discussion: Fumarate reduced perfusion pressure and elicited a peak reduction at the highest dose. Per­fusing the kidney with PMA caused a paradoxical increase in perfusion pressure (70%, p<0.05), compared to baseline. Bolus doses of fumarate reduced blood pressure (-29.3±6.2 mmHg, p<0.05), cortical blood flow (CBF) and increased medullary blood flow (MBF). L-NAME did not abolish the vasodilatory effect of fumarate, but reduced the magnitude of response (50%, p<0.05). PMA did not significantly affect the vasodilatory effect of fumarate (p>0.05).

Conclusion: These data suggest that fumarate exerts a vasodilatory effect on renal and systemic hemodynamics that may partly involve the nitric oxide signaling.

Grapgical abstract:
Search for compounds with antioxidant and antiradical activity among N9-substituted 2-(biphenyl-4-yl)imidazo[1,2-a]benzimidazoles
Authors: Spasov Alexander A. , Brigadirova Anasyasia A. , Zhukovskaya Olga N. , Morkovnik Anatoly S. , Lifanova Yuliya V.
Published: August 2022

Introduction: Biphenyl and imidazobenzimidazole derivatives attract ongoing attention as a combination of these two privileged substructures with promising pharmacological activities. The aim of this study was to synthesize and inves­tigate in vitro antioxidant activity of promising novel compounds: 2-(biphenyl-4-yl)imidazo[1,2-a]benzimidazoles. Materials and methods: The newly synthesized compounds were characterized by IR, 1H NMR and CHBr(Cl)NO analyses. All newly synthesized compounds were screened for their in vitro antioxidant activity: inhibition of lipid per­oxidation (LPO), 2,2’-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+) radical cation decolorization and inhibition of hemoglobin (Hb)-H2O2-induced luminol chemiluminescence. Results and discussion: 2-Amino-3-[(2-biphenyl-4-yl)-2-oxo-ethyl)]-1-R-1Н-benzimidazolium bromides were synthesized, and their cyclization into functionalized imidazo[1,2-a]benzimidazole derivatives was studied. The resulting compounds showed LPO inhibitory activity comparable to that of dibunol. Compounds 1a and 1d (see graphical abstract), containing a methyl or dimethylaminoethyl substituent in the N9 position also proved to be equally highly active in the Hb-H2O2-induced luminol chemiluminescence model, while compound 1a was somewhat more active than 1d in the ABTS• radical scavenging assay. Conclusion: The study showed that compounds 1a and 1d have the highest antioxidant activity. Thus, this new class of 2-(biphenyl-4-yl)imidazo[1,2-a]benzimidazole derivatives represents a valuable leading series with great potential for use as antioxidants and as promising candidates for further efficacy evaluation. Graphical abstract:
Zwischenkriegsodysseen. Zur Figur des Kriegsheimkehrers in drei Romanen von Joseph Roth, Leo Perutz und Bettina Balàka
Authors: Scheidl Günther
Published: August 2022

Les trois romans autrichiens dans cet article traitent du sort de trois rapatriés de la Première Guerre mondiale. Les questions centrales sont de savoir comment gérer l’expérience de la guerre, comment briser la spirale de la violence et redevenir membre de la société et de sa famille. Alors que la littérature de l’entre-deux-guerres fourmille d’exemples, dans lesquels l’échec de la réinsertion a plutôt des causes sociales, les deux romans Die Flucht ohne Ende (1927) de Joseph Roth et Wohin rollst du, Äpfelchen… (1928) de Leo Perutz s’éloignent de ce schéma, dans la mesure où sont offertes aux deux protagonistes principaux des possibilités de réinsertion qu’ils ont déclinées. Les choses s’expliquent bien dans le roman de Roth, car le personnage de Tunda peut difficilement envisager une existence en dehors de la condition militaire et de son identité d’officier. Chez Perutz, le désir de se venger d’un commandant de camp russe empêche toute possibilité de réinsertion dans la société. Balthasar Beck y parvient dans le roman de Bettina Balàka Eisflüstern de 2006, qui, sous couvert d’intrigue policière, déroule un panorama de la période qui fait suite à la Première Guerre mondiale. Beck réussit à réprimer ses pulsions agressives, ce qui lui permet de reprendre place au sein de sa famille.
Vater Kafka. Anmerkungen zum Roman Meine Eltern ( Avi we-imi ) von Aharon Appelfeld
Authors: Corbea-Hoisie Andrei
Published: August 2022

Le présent travail se donne pour objectifs l’examen et l’interprétation du roman tardif d’Aharon Appelfeld Mes parents (titre hébreu original : Avi ve-Imi , en français : Mon père et ma mère ) en se fondant sur la filiation, revendiquée par l’auteur, avec Kafka. Divers axes de réflexion s’entrecroisent et parcourent toute son œuvre narrative, l’histoire-cadre tirant sa matière de la relation, obsessionnelle, avec la Shoah. S’agissant de la fiction, qui a pour décor la région familière de la Bucovine, la reprise du motif de l’impuissance de la bourgeoisie juive assimilée d’Europe orientale à échapper à la catastrophe imminente est vue aussi bien de façon critique par le survivant, qu’habite une conscience israélienne nouvellement acquise, que nourrie de la certitude que l’identité juive est dans son cas inséparable de ses racines spirituelles allemandes. Appelfeld a pour témoin et modèle Kafka dont la représentation de l’homme moderne aliéné s’est approprié l’expérience juive de la souffrance au point de se fondre en elle dans un mouvement d’échange réciproque.
Lactation time influences the composition of Bifidobacterium and Lactobacillus at species level in human breast milk
Authors: Ding M. , Zheng Y. , Liu F. , Tian F. , Ross R.P. , Stanton C. , Yu R. , Zhao J. , Zhang H. , Yang B. , Chen W.
Published: August 2022

Human breast milk is a source of microorganisms for infants that play an important role in building infant gut health and immunity. The bacterial composition in human breast milk is influenced by lactation time. This study aimed to investigate the influence of lactation time on bacteria in breast milk at the genus level and the species levels of Bifidobacterium and Lactobacillus on days 2-4, 8, 14, and 30. Eighteen individuals were recruited and 60 milk samples were collected. The 16S rRNA gene, and the bifidobacterial groEL and lactobacilli groEL genes were used for amplicon sequencing. The results revealed that the alpha diversities of colostrum and transition 1 (day 8) milk were lower than that of transition 2 (day 14) and mature milk. PCoA analysis showed that bacterial composition in colostrum and transition 1 milk differed from transition 2 and mature milk. A lower relative abundance of Blautia was found in colostrum and transition 1 milk compared with mature milk and lower abundances of Ruminococcus, Dorea, and Escherichia-Shigella were found in transition 1 compared with mature milk. Bifidobacterium ruminantium, Limosilactobacillus mucosae, and Ligilactobacillus ruminis were the predominant species across all four lactation stages, while Bifidobacterium bifidum was lower in transition 1, and Bifidobacterium pseudocatenulatum and Bifidobacterium pseudolongum were higher in transition 1 milk. This study indicated that the bacterial composition in colostrum was more similar to that of transition 1 milk, whereas the bacterial community in transition 2 milk was similar to that of mature milk which suggests that bacterial composition in human breast milk shows stage-specific signatures even within a short period at both genus level and Bifidobacterium and Lactobacillus species levels, providing insights into probiotic supplementation for the nursing mother.