bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of Tailabhyanga in Balyawastha and its benefits: A Review Study
Authors: Munjabhau Gore  , Gopal B. Sharma
Published: July 2023

In Ayurveda Tailabhyanga is considered as Snehan therapy in daily routine practice (Dinacharya) to be followed for maintenance of health in healthy individual. This is an oldest of all techniques for healing, preventing diseases and promoting health. Tailabhyanga is also part of pre-therapeutic procedure of Panchkarma, Ayurveda described very scientific approach in Balyawashta as Navjat Balak Paricharya. Oil massage (Tailabhyanga) is therapy that has positive effect on physical growth of babies including weight gain, nourishment, emotional well-being and beauty purpose. The role and importance of Tailabhyanga which are described in ancient are listed according to health promotion of children. Tailabhyanga is the important therapy of traditional Ayurveda in current lifestyle important of Tailabhyanga is ignored by parent's as well as practitioners. So, this article lightens the importance of Tailabhyanga.
Therapeutic and cultural evaluation of Brahma Kamal (Saussurea obvallata (Dc.) Edgew: An endangered potential herb
Authors: Vidhu Singh  , Yashika Singh  , Rishabha Koirala  , Komal Keshwa  , Preeti Tamta  , Thakur Rakesh Singh
Published: July 2023

Background: The essential components of the traditional medical system are plants. A medicinal plant from Uttarakhand known as Saussurea obvallata (DC.) Edgew, is considered to be endangered due to its rich cultural and medical significance. It is found at high altitudes of 3000-4800 meter in the Himalayan region. Many studies have been published on phyto constituents and its traditional uses that shown its therapeutic values. In this article all the published research work and available data on geographical and traditional uses of Brahma Kamal are compiled here. Aim: To increase understanding of S. obvallata's cultural significance, medical uses, and protection against health risks. Methods: Review a list of published original articles and review secondary data from a variety of databases, including PubMed, PubMed Central, Shodhganga, DHARA, Ayush Research Portal, Google Scholar, Medline, Embase, etc., as well as a list of published original papers. Result: Various plant parts of S. obvallata have been used for a variety of ailments, including dysentery, rheumatism, leprosy, bone fractures, nervine debilities, cerebral palsy, paralysis, sexual disorders, lung infections, urinary tract infections, leucoderma, rhinitis, and hyperthermia. Conclusion: The information in review confirms the traditional claims and contributes in providing promising baseline information for the pharmacological use of S. obvallata. The information presented here maybe beneficial for researchers, healthcare professional and pharmaceutical companies to design and develop effective medicines against microorganisms.
A comparative clinical study to evaluate the efficacy of Malatyadi Taila Shiro Abhyanga over Dhurdhuradi Taila Shiro Abhyanga in the management of Darunaka (Dandruff)
Authors: Manasa Panchaxarimath  , Sanjay M Kadlimatti
Published: July 2023

Great individual cleanliness is critical for both well-being and social reasons. Among maintaining great individual cleanliness hair cleanliness is most imperative and necessary too. Darunaka aka dandruff, also known as Pityriasis Captitis, is one of the foremost common and widely seen dermatological maladies that influences most of the world's populace. The cardinal symptoms for Darunaka are Daruna (rough/flakes), Kandu (scalp itching), Rukshata (dry scalp), Kesha Bhumi Prapatana (cracking of the scalp), Kesha Chyuti (hair fall). A clinical study was conducted to assess the comparative effect of Malatyadi Taila over the Dhurdhuradi Taila Shiro Abhyanga in Darunaka (Dandruff). 40 patients with Darunaka were taken and randomly divided into 2 groups consisting of 20 patients in each group such as Dhurdhuradi Taila as Group A and Malatyadi Taila as Group B. The oil application (Shiro Abhyanga) is adopted for both the Taila with a duration of 1 month. Grading of severity were given for clinical signs and symptoms based on the before and after treatment. The overall effect of the study showed 25% of complete cure, 65% of mild cure and 10% of them have felt no change in Group A, and in Group B 80% of complete cure, 15% mildly cure, and 5% have felt no change. Darunaka management certainly benefited from the usage of Malatyadi Taila. There was a substantial improvement in clinical symptoms after just one month, and it was cost effective, adaptable, and safe.
Importance of physician in healthcare system from the perspective of Charaka Samhita
Authors: Sumana Ray Paul
Published: July 2023

According to Ayurveda, a healthcare system is like a table which is stood upon four factors i.e., Bhishaka (physician), Dravya (medicaments), Upasthata (attendant) and Rogi (patient), among which physician is considered to be the most principal factor among others. Charaka Samhita being the foremost compendium of Ayurveda has given much emphasis on various characteristic of an ideal physician along with his duties, functions and other essential aspects. By studying all these textual information one can draw a distinct idea about the importance and role of an ideal physician in the healthcare system as conceptualised by Charaka Samhita. A physician by virtue of his erudite knowledge, commanding capability and rational approach drives the entire healthcare system to its successful accomplishment. Without physician, none of the other three factors can function properly and leads to collapse. It is only the physician who is capable of bringing the other three factors, viz. the patient, the attendant and the medicament to right usage. Even if, these three factors are deficient in certain qualities, the physician can by virtue of his imagination; knowledge and concentration render them useful. The three factors (even if otherwise useful) may turn out to be completely useless in the absence of a well-qualified physician. Thus a physician holds the most important place in a healthcare system by virtue of his textual knowledge, extensive experience, noble character, skill and many other qualities.
A literary review of Tamra (copper) w.s.r. to its role in Hepatomegaly
Authors: Raj Mohan Mishra
Published: July 2023

Rasashastra is a branch of Ayurveda dealing with metal & minerals. The Rasa Aushadhi are the back bone of Ayurvedic medicine. Metal and mineral are the integral part of therapeutics in Ayurveda and Tamra is one such metal which is highly poisonous & several times more poisonous than poison itself because one poison cause only one Dosha (toxic effect) while unpurified and unreduced Tamra may have eight Dosha.[1] Which has been described as Ashtamahadosa in classical text book. but if this Tamra is well processed through all pharmaceuticals process, it can be converted into one of the best and effective medicine. Tamra Bhasma is useful in treatment in various disease condition like Udar Vyadhi, Pandu[2] etc. In this study a descriptive study of Tamra and its therapeutic potential basis which are mentioned in our classical Ayurveda textbook with special reference to its role in Hepatomegaly is studied by searching and analyzing all Ayurvedic and all modern perspective.
A critical review on Samana Vayu apropos regulation of Gastrointestinal Tract
Authors: Tripathi Ritunanda , Shuchi Dubey  , N.K. Prasad
Published: July 2023

Ayurveda believes in the theory that whatever is present, in the external universe is also present in the human body. Understanding the factors that constitute the body provides knowledge regarding the factors which are responsible for its well-being. The complete physiological action of the body can consolidate in Dosha, Dhatus, and Malas, these three are the main constituents of the body. The Tridoshas", control the fundamental physiological functions of the body. Vata being supreme among the three Doshas, conducts and controls all the activities of the body through Vayu. The Samana Vayu lies near the Jatharagni and its Sancharsthan (effective area) is Kostha; its function is Grahana, Pachana, Vivechana, and Munchana of Anna Dravya and providing strength to Agni.  Prana, Samana, and Apana are three types of Vayu, that assist Jatharagni in the process of Anna Pachana. In modern science, a lot of research has been done regarding the factors participating in the regulation of the gastrointestinal tract such as enzymes, hormones, nerves, etc. However, the exact role of Samana Vayu in the regulation of Agni and consequent absorption of different food materials and metabolism followed by excretion, etc. is not properly understood in Ayurveda, leading to confusion between the functions of Samana Vayu, Pachaka Pitta, Kledaka Kapha and even up to the excretory functions of Apana Vayu. This study aims to understand the role of Samana Vayu in the physiology of Pachana through Agni and its regulatory mechanism.
Concept of Krimi and its scientific understanding
Authors: Priyanka Bairagi  , S Abhishek , Anita Dandappanavar  , Abhishek Shukla
Published: July 2023

The term Krimi is frequently used in ancient Ayurveda classics from the Vedic period. In The etiology of many diseases, microbial relation played very important role and it is also a causative factor for various pathological condition like weight loss, Anemia, Vomiting, Headache etc. The Krimi may be external or internal in nature. Their mode of transmission, sign, symptoms are almost same as worm and microbes in contemporary science. They had given the description of structure, Naming of Krimi as far as possible. The Krimi described in ancient text are more or less similar to microbes and helminths mentioned in present time. The term Krimi has been used in broader sense. It indicates all pathogenic and non pathogenic organisms covering wide range of infectious pathogens. Ayurveda has advised specific drugs for specific Krimi. Here an effort has been made to understand the Krimi in all the ways possible.
Holistic Approach to Female Uttar Basti - A Review Article
Authors: Neha Chaudhary  , Shweta Mishra
Published: July 2023

In Ayurveda, Basti is considered as Ardhchikitsa by some Acharyas and as a complete therapeutic procedure by others due to its Vast areas of action. As defined by Acharya Charak, Basti is of three types and among them; Uttar Basti has been highlighted for most of the uro-genital disorders in both males and females. As it gives quick relief and can easily be practiced in OPD basis, it outpowers other systems of medicine and can be used as alternative for invasive intervention. Vaginal douching and Urethral douching have been practiced already but Uttar Basti has a far wider scope in terms of disease diversity. Through this article, an attempt has been made to review Uttarbasti through classical texts to understand the concept of Uttarbasti and to understand its mode of action with its importance in clinical practice.
A conceptual view on Computer Vision Syndrome through an Ayurveda Prospective
Authors: Sharma Sakshi , Mahendra Kumar Sharma
Published: July 2023

Acharya Vagbhat quotes that loss of vision is a loss of life. Vision is our primary connection with this world. With the help of eyes, we can interact with our surroundings in more than a million ways every second. Computer, the knowledge bank of modern life, has emerged as a profession causing vision-related discomfort, ocular fatigue, and systemic effects. Computer Vision Syndrome (CVS) is the new nomenclature to the visual, ocular, and systemic symptoms arising due to the long time and improper working on the computer and is emerging as a pandemic in the 21st century. Approximately 60 million people suffer from Computer Vision Syndrome globally, which leads to a decrease in productivity at work and Quality of life.  Ayurved being an ancient system of medicine has millions of remedies in it, which is useful for all types of disease, whether it is stated directly or not. Ayurved classics quote that if a physician is not able to get a direct description of the disease in Samhitas, he should not feel guilty about that and should treat the condition based on the involvement of Doshas in it. Hence, here an attempt has been made to provide an explanation of Dosha, Dushya & Samprapti of Computer vision syndrome according to Ayurveda.
Ethics in Ayurveda
Authors: Rishabh Gupta  , S.N. Tiwari  , Pravanjan Acharya  , O.P. Shukla
Published: July 2023

Ayurveda means science of life and advises practice of those ways which are good for life and abstinence of those which are harmful.[1] Patients are always looking for quality treatment from their doctors. The basic tools of good medical practice involve professional competence, healthy relationships with patients, and good ethical practice. The regulatory agencies composed “Code of Ethics and Professional Conduct” which is updated time to time. Ayurvedic Practice Guidelines protect the rights of doctors as well as patients. The Ayurvedic Practice Guide includes information on how to practice with the restrictive regimen of standard protocol, which is essential for the physician to follow ethical behaviour because medical practice is directly related to body health. There are many ethical issues associated with medicine that are relevant to everyone. Ayurveda, the traditional science of the Indian medical system, has also prescribed a code of ethics for the practice of medicine, but has not yet been recognized therefore, it is necessary to examine the ethical behaviour of Ayurvedic practice in order to maintain the quality of the Ayurvedic profession. Ethics is the essence of all religions and philosophies as it studies or preaches the practice of those that makes conduct good, leading to happiness in life. The excessive, less or mis-indulgence of Prajna (intellect) or Indiriyartha sanyoga (contact of objects with organs of perception) is mostly due to unethical mode of life. Ayurveda sufficiently throws light on the ethical way of life so that one does not become unhappy or sick and should attain happiness.
Traditional knowledge in Folklore Practices - A Review
Authors: Sreedevi VP  , PN Mini
Published: July 2023

Traditional knowledge, often referred to as TK, is a fundamental concept that is closely tied to the traditions and cultures of different nations across the globe. It primarily encompasses the extensive experiences and enduring practices of specific regional, indigenous, or local communities. Moreover, it includes the collective wisdom, knowledge, teachings, and accumulated experiences of these communities, typically passed down orally from one generation to the next. As it is rooted in the unique knowledge held by ordinary individuals, including ethnic communities residing in specific regions or countries, this knowledge is limited to the genetic and non-genetic resources accessible within their immediate surroundings. This article emphasizes the significance of case studies, which hold potential interest and valuable information for AYUSH doctors and researchers engaged in drug development and related research and development programs. The majority of case studies included in this publication are previously unidentified or less widely known, and may not be documented in conventional Ayurvedic literature.
Conceptual insights of Matravirudha Ahara in Ayurveda
Authors: Shilpa Shankarrao Walkikar
Published: July 2023

Ayurveda is something beyond a remedial framework; it is a science and specialty of reasonable living that guides in accomplishing life span. It puts an accentuation on deterrent and recuperating treatments notwithstanding various approaches to purifying and revival. It can assist every individual with coming to the right conclusions about their sustenance, way of life, and exercise to restore a good arrangement between their body, brain, and mindfulness, to restore a good overall arrangement between their body, psyche, and mindfulness, in this manner ending the spread of sicknesses. Some unacceptable eating routines, propensities, ways of life, contradictory food mixes (e.g., milk and fish, melons and grain, yogurt, and meat or cooked Madhu, and so on), occasional changes, curbed feelings, and stress variables can all act either together or independently to change the equilibrium of Vata, Pitta, and Kapha. As per the idea of the reason, either Vata, Pitta, or Kapha go through exacerbation or insanity which influences the Agni (gastric fire) and creates Ama (poisons). This Ama enters the circulatory system and is circled all through the body, stopping up the channels. Maintenances of poisons in the blood bring about pre-eclampsia. This gathered poisonousness, when deeply grounded, will gradually influence Prana (crucial life energy), Ojas (resistance), and Tejas (cell metabolic energy) and result in sicknesses. This can be nature's endeavor at killing the poisonousness from the body. Each supposed infection is an emergency of Ama poisonousness. Ama is the fundamental interior reason for all illnesses, due to the bothered Doshas.
Holistic approach to the Neuromusculo Diseases related to Spinal Cord and Vertebral Column
Authors: Sheelam Parihar  , Rita Marwaha  , Nisha Bhalerao  , Shradhha Sharma
Published: July 2023

The spinal cord is a complex organization of nerve cells responsible for movement and sensation. It carries signals between the brain and the rest of the body. Spinal cord injuries can range from sensory loss to incomplete or complete paralysis. Spinal cord diseases are a heterogeneous group of conditions that cause damage or dysfunction of the spinal cord. They include infections, inflammatory disorders, vascular diseases and disorders that affect the meninges or perimeningeal spaces that surround the spinal cord. Motor, sensory, reflex, and sphincter abnormalities may be used to determine the location of a lesion within one of four major longitudinal divisions of the spinal cord. The divisions are cervical (C1–C5 spinal cord segments), cervical enlargement (C6–T2), thoracolumbar (T3–L3), and lumbar enlargement (L4–Cd5). A disorder of each of the four regions of the spinal cord results in a combination of neurological signs that is specific for the region involved. Recognition of a characteristic group of clinical signs therefore allows accurate localization of a spinal cord lesion. Spinal Cord disorders are conditions that cause damage and deterioration to the spinal cord. These conditions include Spinal stenosis, Herniated Discs, Degenerative disc disease etc. Symptoms of Spinal Cord Disorders are weakness or paralysis of limbs, loss of sensation, uncontrolled muscle spasms and back pain etc. Having knowledge of the location and structure of the protective spinal cord can help healthcare professionals to provide pain relief for certain procedures.
Role of Kanchnar Guggulu in Ovarian Dermoid Cyst
Authors: Gopal Sahadev Alhat  , Bhalgat Madhuri Sanjay
Published: July 2023

Today we see the age of menarche has dropped to as 10 years of age. In fast growing world, over workload, pesticides rich food, hormone-based fruits and vegetables, stress, over ambition, avoiding pregnancy all are the major causes of these new diseases in modern woman. Premenstrual syndrome, irregular menses, ovarian cyst, uterine fibroids are commonly seen now a days. Due to defective lifestyle of women in modern era, ovarian cyst has become a burning problem in current scenario affecting all age group of women. There is no such effective treatment in modern science rather hormonal therapy and laparoscopy and hormonal therapy has its own harms, regardless of the presence of this disease laparoscopy or surgical management is certainly a treatment option; it is not necessarily the only option. Hormonal therapy is not a ‘cure’. Due to limitation of Modern science, Ayurveda has a great scope in this filed. This is the high time to develop an effective Ayurvedic treatment protocol for its prevention & cure.
Ayurvedic management of Poly Cystic Ovarian Syndrome (Aarthava Kshaya)
Authors: Jyoti Pawar  , Madhuri Bhalgat
Published: July 2023

Poly Cystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, resulting from insulin resistance and the compensatory hyperinsulinemia. This results in adverse effect on multiple organ systems and may result in alteration in serum lipids, anovulation, abnormal uterine bleeding and infertility. According to Ayurvedic view PCOS can be correlated with Aarthava Kshaya. It was revealed that most of subfertility patients who were presented in Osuki Ayurveda Centre suffered from the PCOS. Here is a case report of 28 year old women who presented with irregular menstruation, rapid weight gain and hair loss. On USG she was detected to have bilateral PCO pattern. Based on the clinical features, treated with ayurvedic management.
Ayurvedic management of Trigeminal neuralgia by Jalauka Avacharana - An Experience
Authors: Bishan Kumar  , Mamta
Published: July 2023

Trigeminal neuralgia is neuropathic pain causes intense, stabbing pain throughout the face. Attacks can be sudden, come without warning, and make it difficult or impossible to perform normal activities. It was once considered a suicidal disease. The condition is managed through various medications and surgical procedures. Carbamazepine is the drug of choice. If medicines are not effective or side effects are intolerable then surgery is the choice. But it is associated with complications in most cases after surgery and also pain episodes may recur after some years. Recently LASERs are used as adjunctive in the treatment of trigeminal neuralgia for reduction of pain intensity. In Ayurveda it can be correlated with Ananta Vata and plays important role in management and for better quality of life. In Ayurveda Jalauka is the best treatment modality for pain management and stopping recurrence of disease and being healthy ever. A male patient of age 60 years, diagnosed with Trigeminal Neuralgia was treated with allopathy medications. But did not get satisfactory results. Hence patient approached our centre and got the improvement provided by the therapy was assessed on the basis of signs and symptoms before and after the treatment. The therapy was found safe and effective in controlling signs and symptoms and improving the overall condition of trigeminal neuralgia.
Effect of Ashwagandha Kwatha Dhara in Anidra - A Case Series
Authors: Kavita Kumari  , Santosh Kumar Bhatted
Published: July 2023

Insomnia also known as sleeplessness, is a sleep disorder in which people have trouble in sleeping. There are around 10% to 30% of the adults have insomnia at any given point in time and up to half of people have insomnia in a given year and about 6% of people have insomnia that is not due to another problem and lasts for more than a month. The typical first line of treatment are Sleep hygiene and lifestyle changes but is restricted only to the mild cases, Moderate or severe cases requires medications like sleeping pills, sedatives, antidepressants, antipsychotic drugs like Antihistamines, Benzodiazepines etc. The side effect, dependency and withdrawal symptoms of these drugs are not new to the medical sciences. On the antagonistic part Ayurveda can provide a safe and effective non interventional solution to it by Shirodhara a Panchakarma therapeutic measure. In this case series Ashwagandha Kwatha Dhara was used to see the effect on various criteria like Athens Insomnia Scale Hamilton Anxiety Scale, Hamilton Depression Scale, WHO – Quality of scale (Bref) and Ayurveda Lakshana and an overall improvement of 86.5 % was found in all these criteria’s which was found worth sharing to the medical fraternity for enhancement and its further appraisal.
Integrative Approaches to Cancer Care and Research through Yoga and Herbal Medicines during the Chemotherapy Treatment
Authors: Shankar Rama , Joshi Rashmi Atul , Srivastava Anupam , Prajapati Uday Bhan
Published: July 2023

The present communication is a review on various integrative approaches for the cure of cancer with an involvement of modern methodology, the chemotherapy, radiation, Yoga, and use of herbal medicines. In general, the cancer is manageable as pre and post treatment management by the use of Yoga and herbal medicines. Various types of Yoga and Pranayama keeps the body free from ailments even the serious diseases like cancer. During chemo and radiation therapy of the cancer patient’s number of body disorders are reported, viz., giddiness, nausea, vomiting, and fatigue, etc. To manage these upcoming symptoms Yoga and herbal medicines play very vital role for the management of these disorders. On various literature survey from the world 42 medicinal plants were recorded to manage cancer disorders out of which Allium sativum, Curcuma longa, Coptis chinensis, Hemidesmus indicus, Pistacea integerrima, Tinospora cordifolia and Withania somnifera plays vital role as a preventive and post therapy management of cancer.
Postnatal care with Diet in Ayurveda
Authors: Ghyan Kanwar  , Pramod Kumar Mishra  , Brahmanand Sharma  , Abanikanta Sahoo  , Neha Verma
Published: July 2023

All the living beings in the universe require Aahaar which sustains the life. That is why it is said to be Praaninam Praana, Mahabhaishajya or Brahma in Ayurveda. Obviously, Lawful dietary intake results in Pran- Anuvartan. There is no life without Aahaar. Aahaar and existence of Agni is responsible for Praana. It maintains the equilibrium of Dhatus and helps in prevention of disorders and promotion of health. Nowadays in developing countries, the incidence and prevalence of postnatal morbidity are poorly known. After proper expulsion of placenta, a woman is said to be Sootika in which Vata-Dosha is in Prakopavastha. Improper knowledge of Sootika Kala diet followed by women, mother as well as child may suffer serious complications. There is definite need to study the preventive aspects described in classics. So, the mentioned diet given for puerperium is a medicated diet not a simple diet. Hence, this study will suggest some guidelines for the care of Sootika with diet.
Role of Kasherukadi Yog in treatment of Garbhastrava
Authors: Bhalgat Madhuri  , Dudhale Shubhangi Gajanan
Published: July 2023

All women yearn for and dream of being pregnant. It's crucial to have a healthy pregnancy and birth. Considering Indian women, more likely than those of other races to miscarry their first pregnancy or experience repeated miscarriages. The creation, growth, and pathology of "Garbha" are all well-understood in Ayurveda. Up until the fourth month of pregnancy, Acharya Charaka referred to the expulsion of the foetus as "Garbhsrava" because the sperm and egg are still liquid. However, in the fifth and sixth months of pregnancy, it is referred to as "Garbhapata" because by this time the foetal parts have achieved some stability or have solidified. Ayurveda prescribe herbal preparations for “Garbhasthapaka”. Acharya Sushrut explained various drugs for Garbhsrava Chikitsa. It has the Rasayan property and foetal growth promoting action. The present study is designed to find out the effect of Ayurvedic medicine in Garbhsrava Chikitsa. Kasherukadi Yog is one such combination that have excellent role in treatment of Garbhasrava.
ETHICAL LEADERSHIP BEHAVIOURS OF SCHOOL PRINCIPALS: A COMPARISON OF PUBLIC-PRIVATE SCHOOLS
Authors: Topaloğlu Hakan , Mavi Duran , Uslu Çetin Oya
Published: July 2023

Ethical leadership is the leadership approach that principals use to regulate the communication, climate, behavior, and decision-making processes in the school. It is seen that these studies are carried out in both public and private schools. However, it is difficult to say that these studies reflect the sector and level-based view of ethical leadership holistically. Therefore, in the present study, ethical leadership behaviors of principals in public and private schools were examined at the secondary and high school levels. The study was carried out with a cross-sectional survey, one of the quantitative research designs. Research data were obtained from teachers working in public and private schools in Samsun. In this context, 400 participants' opinions were taken by stratified sampling. Software named SPSS 25.0 and Mplus 8.3 were used for the analysis. Findings illustrate that teachers perceive their principals as brave leaders in both sectors. However, it is understood from the findings that school principals have relatively low scores in respecting social values. Comparisons show that teachers working in public schools perceive their principals as more ethical leaders. In comparisons at the school level, the significant difference in finding the school principal more ethical favors public high schools and public secondary schools. Various inferences were made based on the research results, and suggestions were made.
Curry Jones Sendromlu Hastada Preoperatif Anestezi Yönetimi
Authors: Gezer Yurteri Burcu , Sargın Mehmet
Published: July 2023

Curry-Jones Sendromu (CJS), kraniyofasiyal malformasyonlar, polisindaktili, yamalı deri lezyonları ,göz ve bağırsak anormallikleri ile karakterize nadir görülen bir hastalıktır. Curry Jones Sendromu SMO gen mutasyonuna bağlı olmaktadır. Biz vakamızda Curry Jones Sendrom tanılı çocuk hastaya planlanan operasyon için preoperatif anestezi yaklaşımından bahsettik.
Bibliometric Analysis of Publications on Pandas Syndrome in Psychiatry Research Area
Authors: Şevik Ali Emre , Alkan Sevil
Published: July 2023

Aim: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS Syndrome) is a neuropsychiatric disorder whose diagnosis and treatment are controversial. The goal of this study was to highlight trends and discuss problems in Pandas Syndrome research since 1998 and to assist researchers in identifying new avenues for this field of study.
Material and Method: The Vosviewer program was used to conduct bibliometric analysis on the articles chosen from the Web of Science Core Collection.
Results: The analysis included 361 publications. 2004 was the year with the highest number of publications. In the following years, the number of publications followed an irregular course. The most cited publications were published in 2021 and these publications received 881 citations. The United States (n=191,52.91%), Italy (n=43,11.91%), England (n=32,8.86%), Germany (n=18,4.98%), Sweden (n=13,3.60%), Turkey (n=13,3.60%) and Spain (n=10, 2.77%) were detected as the mostly publishing countries. The United States, the United Kingdom, Italy, and Germany were the countries with the largest number of countries and the most cooperation between countries. The National Institute of Mental Health, Yale University, and Johns Hopkins University were the most prolific institutions.
Conclusion: With this study, we reviewed the global studies on PANDAS in the field of psychiatry and tried to highlight the issues that can be identified as emphasis. According to the study findings, the number of publications on PANDAS is still much lower than expected. Scientific productivity on PANDAS syndrome, which has many unknowns about diagnosis, treatment and etiology, needs to be increased globally.
The Relationship Between ABO-Rh Blood Types and Disease Severity in Children with COVID-19 Infection
Authors: Yeşil Edanur , Özdemir Ali , Erdem Meltem , Özgökçe Özmen Berfin , Akça Mehtap , Bülbül Beyhan , Bursal Duramaz Burcu , Dikme Güldane , Karagüven Aslınur Meryem , Yazan Hakan , Şen Velat , Yılmaz Kamil , Çakır Erkan , Turel Ozden , Çelebi Solmaz , Hacımustafaoğlu Mustafa Kemal , Kuyucu Necdet
Published: July 2023

Aim: The purpose of this study was to evaluate correlation between ABO, Rhesus (Rh) blood type and the disease severity status, pneumonia status in children with COVID-19.
Material and Methods: This is a multicenter study of all children 0.05).
Conclusions: In our study with pediatric population, no difference was detected between blood types and/or Rhesus condition and COVID-19 severity.
Evaluation of locally-available agricultural and industrial waste materials as effective carriers for bacterial inocula in freshwater bioremediation
Authors: Randima Gunasekara Wellappili Arachchige Pipuni , Yapa Yapa Mudiyanselage Ajith Lalith Weerasingha , Masakorala Kanaji , Kumari Widana Gamage Shirani Manel
Published: July 2023

The pollution of freshwater is a pressing global environmental concern, necessitating effective management strategies for polluted aquatic environments. Bioremediation has emerged as a highly promising environmentally friendly approach. However, the selection of suitable candidates capable of effectively degrading or removing pollutants remains a challenging task. The introduction of live candidates, particularly bacteria, into natural environments also poses its own set of difficulties. To address these challenges, immobilizing bacteria within carrier materials has emerged as a leading option. In this study, we meticulously assessed the suitability of four locally-available and low-cost agricultural and industrial waste materials as carriers to transport bacteria into water bodies. The selection criteria encompassed bacteria immobilization capacity, viability, and the resulting water quality after treatment. In order to facilitate comparison, the widely-used sodium alginate was included as a benchmark, and Escherichia coli was employed as the model bacterial inoculum. Our findings revealed that alkaline pre-treatment of corn husk, rice husk, rice straw, and sugarcane bagasse significantly enhanced the bacteria immobilization capacity of these materials. Notably, the viability of bacteria in carrier materials, including sodium alginate, exhibited remarkable resilience, with a count of 107 CFU/g material even after 49 days of storage at room temperature. Moreover, upon determining the quality parameters of the receiving water, the introduction of rice husk and sodium alginate materials demonstrated no significant adverse impact. The quality parameters were well within the acceptable range defined by the World Health Organization standards for drinking water and the Sri Lankan ambient water quality standards for various purposes. Based on the overall performance evaluation, we advocate for the application of rice husk and sodium alginate as superior carriers for delivering bacterial inocula to aquatic environments, particularly in polluted water bodies targeted for bioremediation efforts. Nonetheless, we recommend the collection of carrier materials only after the establishment of bio inoculum in the receiving water, as a precautionary measure to minimize any potential impact on the chemical oxygen demand of the water.
Advancing, empowering, and reshaping Saudi society through integrating e-learning technology into higher education
Authors: Singh Ajay , Alshammari Meshal
Published: July 2023

This research endeavors to propel, empower, and transform Saudi society through the strategic integration of technology-led e-learning within the higher educational institutions of the Kingdom. With the imminent future of learning heavily reliant on technology, the potential for ubiquitous and on-demand knowledge acquisition is set to revolutionize education in the upcoming decades. Our findings underscore the profound influence of technology-led learning on higher education in Saudi Arabia, establishing its pivotal role in driving societal progress. Central to our investigation is an in-depth exploration of diverse e-learning technologies and their profound implications on advancement and empowerment, ultimately instigating a substantial metamorphosis in the fabric of Saudi society. By affording individuals access to a tailored technology-led e-learning platform, the study envisages a profound restructuring of the populace, fostering a skilled and adaptive citizenry. A notable aspect of our research is the discernment of the government's instrumental role as a mediator in facilitating the adoption and implementation of technology-led e-learning, particularly in segments of society where access to these resources remains limited or absent. This mediation bears relevance in the context of the nation's vision for 2030 and forms a cornerstone of our contributions to inform the Ministry of Education and the Kingdom at large about the prospects of embracing a technology-led e-learning system. Moreover, our study delves into the scope and limitations surrounding the implementation of technology-led e-learning within higher education, effectively charting a course for societal transformation by invigorating the higher education system with innovative pedagogy. In conclusion, our research expands the horizons for Saudi learners and educational institutions alike, creating pathways for connectivity, talent acquisition, and representation on the global stage through the medium of advancing technology-led e-learning in higher education within the Kingdom.
Examining Public Awareness of Ageist Terms on Twitter: Content Analysis
Authors: Schramm Emily , Yang Christopher C , Chang Chia-Hsuan , Mulhorn Kristine , Yoshinaga Shushi , Huh-Yoo Jina
Published: July 2023

Background

The World Health Organization, the Centers for Disease Control and Prevention, and the Gerontological Society of America have made efforts to raise awareness on ageist language and propose appropriate terms to denote the older adult population. The COVID-19 pandemic and older adults’ vulnerability to the disease have perpetuated hostile ageist discourse on social media. This is an opportune time to understand the prevalence and use of ageist language and discuss the ways forward.

Objective

This study aimed to understand the prevalence and situated use of ageist terms on Twitter.

Methods

We collected 60.32 million tweets between March and July 2020 containing terms related to COVID-19. We then conducted a mixed methods study comprising a content analysis and a descriptive quantitative analysis.

Results

A total of 58,930 tweets contained the ageist terms “old people” or “elderly.” The more appropriate term “older adult” was found in 11,328 tweets. Twitter users used ageist terms (eg, “old people” and “elderly”) to criticize ageist messages (17/60, 28%), showing a lack of understanding of appropriate terms to describe older adults. Highly hostile ageist content against older adults came from tweets that contained the derogatory terms “old people” (22/30, 73%) or “elderly” (13/30, 43%).

Conclusions

The public discourse observed on Twitter shows a continued lack of understanding of appropriate terms to use when referring to older adults. Effort is needed to eliminate the perpetuation of ageist messages that challenge healthy aging. Our study highlights the need to inform the public about appropriate language use and ageism.
Psychometric Evaluation of the Modes of Health Information Acquisition, Sharing, and Use Questionnaire: Prospective Cross-Sectional Observational Study
Authors: Jones Lenette M , Piscotty Jr Ronald J , Sullivan Stephen , Manzor Mitrzyk Beatriz , Ploutz-Snyder Robert J , Ghosh Bidisha , Veinot Tiffany
Published: July 2023

Background

Health information is a critical resource for individuals with health concerns and conditions, such as hypertension. Enhancing health information behaviors may help individuals to better manage chronic illness. The Modes of Health Information Acquisition, Sharing, and Use (MHIASU) is a 23-item questionnaire that measures how individuals with health risks or chronic illness acquire, share, and use health information. Yet this measure has not been psychometrically evaluated in a large national sample.

Objective

The objective of this study was to evaluate the psychometric properties of the self-administered MHIASU in a large, diverse cohort of individuals living with a chronic illness.

Methods

Sharing Information, a prospective, observational study, was launched in August 2018 and used social media campaigns to advertise to Black women. Individuals who were interested in participating clicked on the advertisements and were redirected to a Qualtrics eligibility screener. To meet eligibility criteria individuals had to self-identify as a Black woman, be diagnosed with hypertension by a health care provider, and live in the United States. A total of 320 Black women with hypertension successfully completed the eligibility screener and then completed a web-based version of the MHIASU questionnaire. We conducted a psychometric evaluation of the MHIASU using exploratory factor analysis. The evaluation included item review, construct validity, and reliability.

Results

Construct validity was established using exploratory factor analysis with principal axis factoring. The analysis was constricted to the expected domains. Interitem correlations were examined for possible item extraction. There were no improvements in factor structure with the removal of items with high interitem correlation (n=3), so all items of the MHIASU were retained. As anticipated, the instrument was found to have 3 subscales: acquisition, sharing, and use. Reliability was high for all 3 subscales, as evidenced by Cronbach α scores of .81 (acquisition), .81 (sharing), and .93 (use). Factor 3 (use of health information) explained the maximum variance (74%).

Conclusions

Construct validity and reliability of the web-based, self-administered MHIASU was demonstrated in a large national cohort of Black women with hypertension. Although this sample was highly educated and may have had higher digital literacy compared to other samples not recruited via social media, the population captured (Black women living with hypertension) are often underrepresented in research and are particularly vulnerable to this chronic condition. Future studies can use the MHIASU to examine health information behavior in other diverse populations managing health concerns and conditions.
Severity Classification Using Dynamic Time Warping–Based Voice Biomarkers for Patients With COVID-19: Feasibility Cross-Sectional Study (Preprint)
Authors: Watase Teruhisa , Omiya Yasuhiro , Tokuno Shinichi
Published: July 2023

BACKGROUND

In Japan, individuals with mild COVID-19 illness previously required to be monitored in designated areas and were hospitalized only if their condition worsened to moderate illness or worse. Daily monitoring using a pulse oximeter was a crucial indicator for hospitalization. However, a drastic increase in the number of patients resulted in a shortage of pulse oximeters for monitoring. Therefore, an alternative and cost-effective method for monitoring patients with mild illness was required. Previous studies have shown that voice biomarkers for Parkinson disease or Alzheimer disease are useful for classifying or monitoring symptoms; thus, we tried to adapt voice biomarkers for classifying the severity of COVID-19 using a dynamic time warping (DTW) algorithm where voice wavelets can be treated as 2D features; the differences between wavelet features are calculated as scores.

OBJECTIVE

This feasibility study aimed to test whether DTW-based indices can generate voice biomarkers for a binary classification model using COVID-19 patients’ voices to distinguish moderate illness from mild illness at a significant level.

METHODS

We conducted a cross-sectional study using voice samples of COVID-19 patients. Three kinds of long vowels were processed into 10-cycle waveforms with standardized power and time axes. The DTW-based indices were generated by all pairs of waveforms and tested with the Mann-Whitney U test (α<.01) and verified with a linear discrimination analysis and confusion matrix to determine which indices were better for binary classification of disease severity. A binary classification model was generated based on a generalized linear model (GLM) using the most promising indices as predictors. The receiver operating characteristic curve/area under the curve (ROC/AUC) validated the model performance, and the confusion matrix calculated the model accuracy.

RESULTS

Participants in this study (n=295) were infected with COVID-19 between June 2021 and March 2022, were aged 20 years or older, and recuperated in Kanagawa prefecture. Voice samples (n=110) were selected from the participants’ attribution matrix based on age group, sex, time of infection, and whether they had mild illness (n=61) or moderate illness (n=49). The DTW-based variance indices were found to be significant (P<.001, except for 1 of 6 indices), with a balanced accuracy in the range between 79% and 88.6% for the /a/, /e/, and /u/ vowel sounds. The GLM achieved a high balance accuracy of 86.3% (for /a/), 80.2% (for /e/), and 88% (for /u/) and ROC/AUC of 94.8% (95% CI 90.6%-94.8%) for /a/, 86.5% (95% CI 79.8%-86.5%) for /e/, and 95.6% (95% CI 92.1%-95.6%) for /u/.

CONCLUSIONS

The proposed model can be a voice biomarker for an alternative and cost-effective method of monitoring the progress of COVID-19 patients in care.
A Comprehensive Analysis of the Steps Involved in Testing of Hypotheses
Authors: Akhileshwari A.
Published: July 2023

Abstract: Data analysis plays a crucial role in research across various disciplines. It involves the systematic examination, interpretation, and transformation of raw data into meaningful insights and conclusions. There are numerous methods of data analysis available, and the choice of method depends on the research question, data type, and objectives of the study. Among them, Hypothesis testing is one of the common methods used in inferential statistics. Hypothesis testing allows researchers to test the significance of relationships, differences between groups, or the presence of an effect. This article makes an attempt to investigate the various stages involved in hypothesis testing in greater detail.
Various Software Testing Techniques, their Implementation and Significance on Banking Applications: In Context of Bangladesh
Authors: Khan Sarah Nuzhat , Akter Sanjida , Hasan Shihab Z , Sharmin Dilruba
Published: July 2023

Abstract: Software testing is the process of identifying bugs or errors in developed software. Consequently, this process offers interested individuals with precise details on the product's quality. Software testing is done not only to ensure that the program behaves correctly or not, but to check whether it satisfies the user’s requirements and expectations as well. The testing of banking software is very important since they handle millions of transactions and are related to customers directly. Proper testing of the banking applications ensures that all operations are carried out accurately and remain safe and secure. The main objective of this paper is to provide an overview of various software testing techniques, their implementation and significance on the banking applications of Bangladesh.
The effectiveness of AR e-module of flower structure material on biology students’ science literacy
Authors: Sulisetijono S. , Sunarmi S. , Rochmah Azizah Nur
Published: July 2023

The electronic-module (e-module) is one of the teaching materials needed so that the learning process can take place optimally. E-module owned by UM biology students generally do not use the latest technology. Augmented Reality (AR) is a form of technology where there is a process of integrating the virtual world with the real world. Not a few students experience difficulties in understanding the flower structure material. Student scientific literacy is still far from what is expected. The research conducted is Research and Development with the Lee and Owens Development Model. Data collection was carried out during October-December 2022. The technique of analyzing quantitative descriptive data. The subjects in this study were 37 biology students class of 2021 without any differences in gender, age and study program. The results of the effectiveness of the AR electronic-module based on n-gain calculations obtained a score of 0.7 where on that score the AR e-module was categorized as quite effective in increasing scientific literacy. It is hoped that in the future there will be teaching materials and media that can improve some of the competencies needed by the latest generation.