bluuebunny/crossref_metadata_2025 huggingface dataset:
Longshore movements and site fidelity of the iconic giant trevally Caranx ignobilis from southern Africa, determined using passive acoustic telemetry
Authors: Dixon RB , Murray TS , Mann BQ , Cowley PD , Daly R , Filmalter JD
Published: January 2024

Giant trevally Caranx ignobilis are iconic, apex marine predators globally distributed in tropical to subtropical regions, where they are of high importance to ecosystems and fisheries. During summer, adults aggregate for spawning, making them vulnerable to overfishing. The world’s largest C. ignobilis aggregation has been recorded in southern Mozambique, but the year-round movements of these fish required further investigation. To assess movement patterns of C. ignobilis along the southern African coast, 36 adult fish were acoustically tagged and monitored along the east coast between Santa Maria in southern Mozambique and Port St Johns in the Eastern Cape, South Africa, for over 5 yr using an extensive passive acoustic receiver array. All acoustically tagged C. ignobilis were recorded in southern Mozambique between November and January each year (with minor exceptions), moving distances up to a maximum of 632 km in one direction. These movements were fast and direct, with maximum travelling speeds of up to 130 km d-1. When not migrating, South African-based fish showed consistent inter-annual fidelity to individual linear areas of space use equivalent to home ranges. Although the coastal length of these areas varied considerably between individuals, even the mean length (92 km) was greater than any previously recorded C. ignobilis home range, globally. Findings from this study, including the value of no-take marine protected areas, are of global ecological interest and have implications for local fisheries management. Protecting these vulnerable aggregations is of the utmost importance for the future of this species in southern African waters and elsewhere.
On The Edge Of HTA
Authors:   , Hogervorst Milou Amber
Published: January 2024

This thesis aimed to investigate how to prepare health technology assessment (HTA) organisations for the assessment of future complex medicines for reimbursement.

The first part of the thesis studied the current challenges for HTA and discovered that these mostly stem from unavailable data. HTA assessors were positive towards using patient registry real-world data (RWD) in the case of complex medicines. However, many hurdles remain. For example, a discrepancy was seen between methods for comparing single-arm trials with RWD-based comparators in the literature and those used in practice. Tumour-agnostic therapies challenged current approaches to defining eligible patients and evidence generation. Variations in accepting uncertainties led to differences in adopting the agnostic indication across decision-makers.

The second part focused on the current status of alignment between regulatory reviews, HTA reports and clinical guidelines (CGs). For multiple sclerosis medicines, variations were observed in the recommended treatment lines and sub-indications. Time lags exist between HTA report publication and clinical guideline uptake. Descriptions of recommended patient populations for oncology medicines evolved heavily throughout the lifecycle, highlighting the complexity of evidence-based decision-making for eligible patients.

The third part investigated ways to improve alignment among regulatory authorities, HTA organisations, and CG developers. Focus group discussions revealed that alignment might be achieved through similar definitions and methods, and ‘multi-stakeholder dialogues’ to set evidence requirements followed by ‘joint parallel scientific consultations’. Additionally, guidance was developed which can be used to manage uncertainty throughout the drug development and evaluation process.

In conclusion, this thesis underscores the need for HTA to adapt to the evolving healthcare landscape to prepare for future complex medicines.
Lidocaine-containing Euro-Colins solution prevents renal injury in the isolated perfused canine kidney exposed to prolonged cold ischemia
Authors: Erkasap N , Ates E , Erkasap S , Kaygisiz Z
Published: January 2024

Previous studies have reported a decreased incidence of delayed graft function after cadaveric transplantation with the use of lidocaine pretreatment of the donor. We evaluated the effects of lidocaine on prolonged cold ischemia and reperfusion injury in a canine model of isolated kidney perfusion (IPK). The purpose of this study was to evaluate the renal function of isolated perfused canine kidneys after 48 h of cold storage with Euro-Collins (EC) solution or EC solution plus lidocaine. Isolated perfused canine kidneys were randomized into four groups which contained six kidneys: I) cold flush with EC solution and immediately reperfused, II) cold flush with EC solution plus lidocaine and immediately reperfused, III) 48 h of cold storage with EC and reperfusion, IV) 48 h of cold storage with EC solution plus lidocaine and reperfusion. The measured renal functions were glomerular filtration rate, urine production, perfusate flow, urinary lactic dehydrogenase (ULDH), Na reabsorptive capacity, and tissue MDA levels. Histological examination was performed after reperfusion. The tubular functions of kidneys preserved with EC solution containing lidocaine were better when compared with the kidneys preserved with EC alone. Tubular injury marker levels (ULDH) in group IV were significantly lower than in group III and lidocaine also reduced lipid peroxidation during reperfusion. This is in agreement with the histological results. The results of the present study can be taken as evidence of the cytoprotective effect of lidocaine, which may therefore be accepted as a useful agent for kidney preservation.
Mitochondrial membrane potential in cardiac myocytes
Authors: Škárka L , Ošťádal B
Published: January 2024

Mitochondria are involved in cellular functions that transcend the traditional role of these organelles as the energy factory of the cell. Their relative inaccessibility and the difficulties involved in attempts to study them in their natural environment - the cytosol - has delayed much of this understanding and they still have many secrets to yield. One of the relatively new fields in this respect is undoubtedly the analysis of mitochondrial membrane potential. The realization that its alteration may have important pathophysiological consequences has led to an increased interest in measuring this variable in a variety of biological settings, including cardiovascular diseases. Measurements of mitochondrial membrane potential tell us much about the role of mitochondria in normal cell function and in processes leading to cell death. However, we must be aware of the limitations of using isolated mitochondria, single cells and different fluorescent indicators.
Dataset of the ongoing project on review of physical parameters of star forming galaxies in SDSS.
Authors: Luke Kevin
Published: January 2024

5000 nearby star forming galaxies are being analyzed for their physical properties . The goal of this study is to reproduce previous research done on mass-metallicity relations for star formation galaxies as well as release new findings in the correlation between various physical parameters. For the study, a series codes were written in Python to collect and study the data. The codes perform SQL queries, data reduction, analysis and of the data products is a unified table which contains vast data on these nearby 5000 star forming galaxies. In this work the generated table from the codes is presented. The table contains A) Photometry, B) Spectrometry, C) Physical Parameters, D) Emission Line Data. A paper containing the study will be released in future.
Comparison of the Effectiveness of Counseling with Social Media, Animation and Short Films in Improving Perception and Motivation to Do Physical Activity in Adolescents
Authors: Razi Pahrur , Junita Junita , Marsofely Reka Lagora , Marleni Wisuda Andeka , Iksarudin Iksarudin
Published: January 2024

Physical activity is an essential component for health, low physical activity in Indonesia causes a high death rate, with 70% of all deaths among adults (including due to heart and lung disease). Therefore, efforts are needed to increase healthy lifestyles, especially physical activity, by providing health information through the media. The purpose of this study was to compare the effectiveness of counseling with social media, animation and short films as health promotion media to increase perceptions and motivation to do physical activity in adolescents. The design of this study is Quasi Experiment with a total sample of 180 people taken by total sampling. The data collection technique uses a physical activity questionnaire. Data analysis using the Anova test. The results of the analysis obtained that counseling with short films was more effective in increasing perceptions and motivation to carry out physical activities in adolescents at SMAN 3 Muaro Jambi indicated by a significance value at 0.000 (p <0.05) compared to social media and animation. There was a more significant increase in perception and motivation to do physical activity after counseling with short films compared to counseling using social media and animation for teenagers at SMAN 3 Muaro Jambi. Suggestions for further research are to examine the factors that influence perceptions and motivation for physical activity in adolescents.
Ethical Issues in Global Pandemic Covid-19: Attitudes and Perceptions of the People of Bandung City Toward Contact Tracing and the Confidentiality Issues it Can Raise
Authors: Hashibah Hasna , Mayasari Wulan , Syukriani Yoni Fuadah
Published: January 2024

The COVID-19 pandemic has created an innovative space for technology to become a solution, which, if implemented effectively, can help reduce the negative impact of the pandemic on society. For example, contact tracing, which if done manually, requires more resources and takes a lot of time, even though the spread of COVID-19 is happening very quickly, so a faster task force response is also needed. This research aims to determine public perceptions of confidentiality issues that may arise from implementing COVID-19 contact tracing, as well as public attitudes towards implementing COVID-19 contact tracing. This research will use a quantitative study method using a cross-sectional method. The researchers used a phenomenological theoretical approach to find out how people view contact tracing. The results of this research show that the majority of people in Bandung City who were respondents to this research have a positive attitude towards contact tracing and support the implementation of contact tracing. Most of the people in Bandung City who were respondents to this research had a good perception of contact tracing and felt that their privacy would not be disturbed by contact tracing. So the government needs to ensure that the public can easily access the contact tracing method used. Health officials need to explain contact tracing in a way that is easy for the public to understand so that the public understands the purpose of implementing contact tracing. And the public should also seek the latest information about health and obey the recommendations of the government and health officials.
Exploring Media-Based Interventions for Adolescent Mental Health: Literature Review
Authors: Choirunissa Risza , Nugraheni Sri Achadi , Purnami Cahya Tri , Wahyuningsih Nur Endah
Published: January 2024

Media-based interventions show promise in addressing the rising mental health concerns among adolescents, surpassing challenges associated with traditional care. This review critically assesses the effectiveness of media-based interventions in promoting adolescent mental health, with a specific focus on social media, digital applications, and film. The methodology employs a comprehensive approach, utilizing Google Scholar, Scopus, and PubMed databases (2012-2022) with keywords such as "mental health," "media," and "adolescents." the methodology is refined for enhanced clarity, explicitly detailing the search strategy, inclusion and exclusion criteria, and selection process. Findings from the analysis of 13 selected articles highlight promising outcomes of digital interventions in screening and treating mental disorders in adolescents. Emphasizing scalability, accessibility, and personalization benefits, the review recognizes the importance of addressing privacy concerns and the potential drawbacks of relying solely on digital platforms. Additionally, it emphasizes the impact of using booklets for mental health self-management in schools. The review improves organization and flow, eliminating repetition for a clearer presentation of information, providing a detailed evaluation of their strengths and limitations, enhancing the overall credibility of the review. the abstract explicitly discusses limitations related to inclusion criteria, such as language restrictions and the exclusion of specific study designs. This comprehensive approach contributes to a more robust understanding of the literature, providing valuable insights for researchers, practitioners, and policymakers involved in developing effective interventions for adolescent mental health. The implications stress the need for further research, evidence-based intervention development, and considerations for implementation and user experience in digital interventions.
Caring Improvement with An Analysis of The Causes of Emotional Exhaustion in Professional Students
Authors: Putri Prestasianita , Susanti Ika Adelia , Afandi Alfid Tri
Published: January 2024

The demand for quality services to patients and families continues to increase, especially for nursing services, so it requires nurses who have good caring. Students of the nursing profession who are future nurse candidates, cannot be separated from these demands. These demands can have the potential to bring emotional exhaustion to students. Emotional exhaustion can be caused by social support, workload, and self-efficacy. The purpose of this study was to analyze the increase in caring based on the analysis of the causes of emotional fatigue in nursing profession students. The research design in this study is a quantitative method with a cross sectional approach. The population of this study is professional students in two institutions in Jember. The number of samples in this study was 150 respondents, with accidental sampling techniques. Data taken from this study are caring behavior, self-efficacy, support, workload, and emotional exhaustion. In general, the results of this study were found that there was a relationship between social support and emotional fatigue (p-value = <0.0000, B: -0.986), there was a relationship between workload and emotional fatigue (p-value = <0.0000, B: 0.372), there was no relationship between self-efficacy and emotional fatigue (p-value = 0.356, B: -0.84) and there was a relationship between emotional fatigue and caring behavior (p-value = 0.002, correlation coefficient: 0.112). Caring can be improved by means of support from students' families, educational institutions and places of practice and calculating the workload experienced by students when carrying out practice.
Mapping of Important HIV/AIDS Hotspots in Palu City Following Natural Disaster
Authors: Arwan Arwan , Fadjriah Rasyika Nurul , Syam Sadli , Yani Ahmad
Published: January 2024

This study aims to obtain a map of the distribution of HIV and AIDS Key Population Hotspots based on the criteria for MSM, Waria and FSW after the natural disaster in 2018. The remapping method uses a Geographic Information System (GIS) application. The data processing technique uses the waterfall model scheme, namely, completing the application in a structured or sequential manner, where a stage must be completed first before going to the next stage. No Ethical consideration is needed. The shift in key population hotspot data from 2017and to 2022 data and then Natural Disasters (Earthquake, Liquefaction and Tsunami) in 2018 had an impact on geographical location shifts with conditions in 2017, 4 Districts became key population hotspot locations with 29 hotspots while in 2022 14 key population hotspots were found consisting of 5 sub-districts, so there was an additional 1 sub-district which became a geographically shifting hotspot. Features of activity hubs centered on major population centers, such as hotels, boarding houses, salons, cafés, clubs, city parks, and malls in 2017; in 2022, other amenities like laundry will be included. Male Fellow (MSM), Female Sex Workers (FSW), and Transgender are the features of the major population hotspots since 2017, however in 2022 Natural Disasters (Earthquake, Liquefaction, and Tsunami) in 2018 did not suffer a shift.
Characterization of DNA Quality, TPOX Locus, TH01 Locus in Seawater Soaked Nails in Forensic Identification
Authors: Utomo Ratno Tri , Endarini Lully Hanni , Yudianto Ahmad , Christyaningsih Juliana
Published: January 2024

Forensic science is multiplying. One of them is the identification of events at sea. Of course, the victim’s body can be submerged in seawater for days so that components in seawater can affect the victim’s body. This research aimed to see the effect of storage time on the level and purity of DNA in nail samples. Identification of nail DNA using the Polymerase Chain Reaction (PCR) method. The DNA purity test examines nail samples using a spectrophotometer read at 260 and 280 nm wavelengths. Measurement of DNA levels using the PCR instrument on the STR TPOX locus, the result was 32.02 ug/uL on positive control, 36.73 ug/uL in seawater immersion on the 2nd day, 35.35 ug/uL in seawater immersion on the 7th day, and 34.5 ug/uL in seawater immersion on the 20th day. At the STR TH01 locus, the result was 32.155 ug/uL on positive control, 38.05 ug/uL on the 2nd day of immersion in seawater, 35.18 ug/uL on the 7th day, and 33.88 ug/uL on the 20th day. Results Examination of the Total Plate Number of seawater on the 2nd day, 7th day, and 20th day of immersion found no colonies of germ colony growth. This study obtained sufficient DNA purity from the 2nd day, 7th day and 20th day. So that the samples could be analyzed for DNA levels, the result obtained from the study showed a decrease in DNA levels at the TPOX Locus and TH01 Locus from the 2nd day, 7th day, and 20th day.
Nutritional Contribution of Awaous sp Small Indigeneous Fish Powder Important for the First 1000 Days of Life
Authors: Bahja Bahja , Hartini Diah Ayu , Ansar
Published: January 2024

Research facts prove that small-sized fish are essential nutrition during the first 1000 days of life. Central Sulawesi Province has an endemic small-sized marine fish species locally known as duo or penja fish (Awaous sp), which has not been studied for its bio-mineral content. This study aimed to analyze the moisture, ash, protein, calcium, iron, and zinc content in Awaous sp protein flour. This research was a descriptive laboratory study conducted at the Ilmu Bahan Makanan Laboratory Department of Nutrition Poltekkes Kemenkes Palu and PT. Saraswanti Indo Genetech Laboratory, Bogor, West Java, from January to September 2023. The sampling technique used purposive sampling, which involved purchasing fish from the local market in Palu city. Awaous sp protein flour had a moisture, ash, protein, Ca, Fe, and Zn content of 3.89%, 9.71%, 73.53%, 2316.88 mg/100g, 24.54 mg/100g, and 8.97 mg/100g, respectively. The contribution per serving of 145 grams of Awaous sp fish flour met the nutritional requirements (Recommended Dietary Allowances - RDA) for protein, Ca, Fe, and Zn per person per day for infants aged 6-11 months, children aged 1-3 years, pregnant women, and lactating women. Awaous sp protein flour had higher protein and Fe content compared to other small fish and had the potential to meet RDA requirements. Therefore, consuming Awaous sp protein flour as part of the daily diet can be a suitable strategy to address nutritional deficiencies during the first 1000 days of life for residents in Central Sulawesi.
The Relationship Between Nutritional Status and The Quality of Life of Chronic Kidney Disease Patients Undergoing Hemodialysis
Authors: Collein Irsanty , Hafid Fahmi , Ismunandar Ismunandar
Published: January 2024

Patients undergoing hemodialysis for a period of more than 3 years tend to experience malnutrition due to inadequate food intake, diseases of the digestive tract, eating restrictions, drugs that cause impaired nutrient absorption, inadequate dialysis, and comorbidities. This study aimed to determine the relationship between nutritional status and the quality of life of chronic kidney disease patients undergoing hemodialysis in Palu. This study used a cross-sectional design to determine the correlation or relationship between 2 variables. Data were analyzed using the Pearson correlation test. The sampling formula determined the number of samples to test the hypothesis on the average of two populations with 108 respondents. This study was carried out in 2 hemodialysis units in Palu. The samples involved in this study were selected by simple random sampling. The results of this study show that most respondents are in the age range of > 55 years, with 41 people (48.1%); are female, with 56 people (51.9%); have a high school education, with 46 people (42.6%); are working, with 81 people (75%) while the remainings are retirees and housewives; and have hypertension as their comorbid disease, with 56 people (51.9%). There is a relationship between nutritional status and overall quality of life, based on the SGA p-value of 0.016 (p-value < 0.05) and based on the MIS p-value of 0.004 (p-value < 0.05), with the strength of the relationship being weak. The conclusion is there is a relationship between nutritional status and the quality of life of CKD patients undergoing hemodialysis. It is hoped that nurses can pay more attention to the nutritional status of CKD patients undergoing hemodialysis.
The Role of Schools in Improving Abilities Disaster Preparedness: Nursing Perspective
Authors: Muhammad Al Azhar , Suni Arsad , Murwidi Imam Cahyo , Sudrajat Ace
Published: January 2024

Earthquake disasters can occur at any time and humans are not yet able to detect when they can occur. Children are included in a group that is vulnerable to the impact of disasters because of their lack of knowledge regarding disaster mitigation. To minimize the impact of disaster events, education on disaster mitigation is needed. To determine the influence of the school's role in increasing students' disaster preparedness abilities in junior high schools in Ternate City. Quasi-experimental research type with a one-group pre-post test design. Data were analyzed using the non-parametric Wilcoxon signed-rank test. The research subjects consisted of teachers (seven respondents) and students (90 respondents). The data were processed using the non-parametric Wilcoxon signed-rank test. The analysis results showed that asymp. sign. (2-tailed) The teacher's score is 0.018 and the student's score is 0.000, where the value of 0.000 is smaller than p value = 0.05, so it can be concluded that there is an increase in disaster preparedness abilities among schoolteachers and students. The role of schools is very important in disseminating disaster mitigation education as basic knowledge that requires learning as early as possible, so that a culture of disaster mitigation grows both before, during, and after a disaster. There was an increase in the ability of teachers and students at school after a disaster preparedness simulation was carried out at a junior high school in Ternate City.
Impact of Policies and Supervision on Health Worker Satisfaction at Bahteramas Hospital
Authors: Risky Sartini , Ardiansyah Ririn Teguh , Firmansyah Firmansyah
Published: January 2024

Providing quality services is inseparable from human resources that produce good performance and achievement. One of the factors related to the performance or work performance of nurses is the low satisfaction of a person with their job. Currently, it is known that the main problem that often arises in human resource management is how to find the best way to achieve employee job satisfaction. Employee complaints about supervision that is very rarely carried out. This makes employees feel that their work is not supervised. This study aims to study the relationship between organizational policies and supervision with the satisfaction of health workers in the BLUD inpatient room of Bahteramas Hospital. This research is a quantitative study with a cross-sectional study approach, and research was conducted on February 2023 in the inpatient room of Bahteramas Hospital. The population in this study were all health workers who worked in the BLUD inpatient room of Bahteramas Hospital, totaling 213 people with a sample of 139 respondents. Data analysis was carried out computerized using the SPSS version 25.0 program, to analyze the relationship between the independent and dependent variables together, the Logistic Regression test was used. Results of the analysis show that all variables that have a probability value (p-value) <0.05 include organizational policies (p=0.141), and supervision (p=0.032). These results indicate that the supervision variable has a significant relationship. Meanwhile, the organizational policy variable does not have a significant relationship with the satisfaction of health workers in the BLUD Inpatient Room of Bahteramas Hospital. There is a moderate relationship between organizational policies and supervision with the satisfaction of health workers in the BLUD Inpatient Room of Bahteramas Hospital.
Dietary Regulation As A Factor Predicting Quality of Life in Diabetic Peripheral Neuropathy Patients
Authors: Ritonga Sukhri Herianto , Decroli Eva , Prahastuti Brian Sri , Usman Elly , Mudjiran Mudjiran , Bachtiar Adang , Afriwardi Afriwardi , Yetti Husna
Published: January 2024

Diabetic peripheral neuropathy is a complication of diabetes mellitus with the number of sufferers continuing to increase from time to time. A decrease in quality of life occurs as this disease progresses, both in physical, mental, and social aspects. Controlling risk factors for declining quality of life needs to be done early, one of the risk factors for declining quality of life is diet. The aim of this research is to analyze dietary regulation as a predictive factor for quality of life in diabetic peripheral neuropathy sufferers. The type of research used is quantitative research with a cross-sectional approach. The respondents in the study were 210 diabetic peripheral neuropathy sufferers who were selected using consecutive sampling techniques. Data collection uses a questionnaire that meets the existing validity and reliability criteria. The data analysis used in this research is SEM PLS analysis. The results show that dietary regulation has a positive influence on quality of life (r=0.236, p=0.0001). Dietary regulation has an effect size on quality of life (f square = 0.095) and also has the ability to predict quality of life well (Q square = 0.232). Dietary regulation is also feasible and suitable in explaining interactions between variables (NFI = 0.540; SRMR = 0.99). The conclusion is dietary regulation can be a good predictive factor for quality of life, so that by improving the diet of diabetic peripheral neuropathy sufferers it will be possible to improve their quality of life.
Designing of a High-Quality CPR Simulation Game Clinical Scenario for Nursing Students: A Qualitative Study
Authors: Laksmi Ida Ayu Agung , Susila I Made Dwie Pradnya , Triana Komang Yogi
Published: January 2024

Cardiopulmonary resuscitation (CPR) is an important skill for nursing students. The process of learning high-quality CPR with a simulation-based learning method can be developed into a simulation game. In order to develop a CPR HQ simulation game, a clinical scenario that can be used as a guide in carrying out storyboards is needed. This research aims to formulate a simulation scenario that will serve as the basis for developing a high-quality CPR simulation game to increase nursing students' competency. This qualitative research uses a Participatory Action Research (PAR) approach by inviting 15 respondents from the prospective user population, namely Emergency Nursing Lecturers, Emergency Room Nurses, BLS Trainers, and nursing students, to carry out Focus Group Discussions. The study's results revealed clinical scenarios that were arranged based on 4 themes, including 1) suitability of the competency being tested, 2) minimum competency for 5 cycles of CPR, 3) settings in the pre-and intrahospital scope, and 4) choice of patient outcome. These components are crucial when designing simulation scenarios that support students’ cognitive processes to achieve High-Quality CPR in nursing students. Thus, the results of this research can then be used as a guide in developing the HQ-CPR game as a learning medium for nursing students.
Meningkatkan Sistem Imunitas Pada Lansia Melalui Kegiatan Fisik Di Masa Pandemi Covid-19
Authors: Nurarifah Nurarifah , Damayanti Risna
Published: January 2024

Covid-19 dinyatakan sebagai pandemi dunia oleh WHO. Kasus Covid-19 mengalami peningkatan dan meluas ke seluruh wilayah di Indonesia sehingga diterbitkan Peraturan Pemerintah nomor 21 tahun 2020 tentang Pembatasan Nasional Berskala Besar (PSBB). Kasus covid-19 paling banyak terjadi pada kelompok rentan seperti masyarakat yang memiliki penyakit penyerta (komorbid), lansia, gangguan imunitas, dan obesitas. Lansia sebagai kelompok rentan yang memiliki resiko tinggi mengalami gejala berat sampai kematian. Tindakan pencegahan penularan Covid-19 sangat penting untuk dilakukan dengan menerapkan pola hidup bersih dan sehat. Adanya PSBB menyebabkan terbatasnya aktifitas yang dapat dilakukan selama stay at home yang dapat menyebabkan inaktifitas dan berpengaruh terhadap penurunan sistem imun pada lansia. Berdasarkan data diatas perlu adanya kegiatan penyuluhan yang bertujuan untuk meningkatkan pengetahuan lansia tentang pentingnya meningkatkan imunitas tubuh dengan aktifitas fisik olaraga sehingga diharapkan akan meningkatkan derajat kesehatan dan mutu kehidupan masyarakat dalam menghadapi pandemi Covid-19. Kegiatan ini dilaksanakan di Desa Moncongloe Lappara,  Kecamatan Moncongloe, Kabupaten Maros,  Sulawesi Selatan pada bulan Juni 2020. Khalayak sasaran yaitu warga lansia desa Moncongloe Lappara. Metode yang dilakukan berupa promosi kesehatan dan  penyuluhan kesehatan.  Kesehatan secara luring dengan menerapkan protokol kesehatan. Hasil dari kegiatan pengabdian masyarakat ini diperoleh bahwa lansia dapat memahami pentingnya kegiatan olaraga untuk meningkatkan imunitas apabila dilakukan teratur yang dapat mencegah penularan Covid-19. Kegiatan penyuluhan ini dapat pada posyandu lansia khususnya dalam melakukan aktifitas fisik seperti olaraga atau senam lansia.
Peningkatan Pengelolaan Diri melalui Edukasi KADO pada Pasien Penyakit Ginjal Stadium Awal dan Pengaturan Pola Makan di Wilayah Kerja Puskemas Talise
Authors: Collein Irsanty , Aminuddin  , Nurjaya
Published: January 2024

Edukasi pasien penyakit ginjal kronik penting dilakukan untuk meningkatkan kualitas hidup dan mempertahankan pasien tetap dalam kondisi yang stabil. Salah satu edukasi yang dapat diberikan adalah topik terkait diet dan pengaturan pola makan. Tujuan pengabmas adalah untuk mengetahui pengaruh dari edukasi yang diberikan terhadap perubahan tingkat pengetahuan pasien PGK stadium awal. Metode kegiatan adalah edukasi yang diberikan kepada pasien PGK stadium awal di wilayah kerja Puskesmas Talise. Metode yang digunakan adalah sosialisasi dan simulasi dengan menggunakan aplikasi android KADOic dan pembagian leaflet pada tanggal 12 Agustus 2023. Tahapan yang dilakukan adalah persiapan dan pelaksanaan. Untuk mengetahui keberhasilan pelaksanaan kegiatan pengabmas dilakukan evaluasi untuk menilai pengaruh edukasi terhadap tingkat pengetahuan dengan memberikan sejumlah pertanyaan. Hasil yang diperoleh adalah terdapat peningkatan pengetahuan responden yang diukur dengan uji paired t-test, masyarakat antusias dalam kegiatan penyuluhan. Edukasi yang diberikan dapat meningkatkan pengetahuan responden tentang diet pada pasien PGK stadium awal dan pengaturan pola makan.
Behavior of Exclusive Breastfeeding for Mothers of Babies over 6-12 Months in Tanantovea Sub-District, District Of Donggala.
Authors: Masulili Fitria , Jurana
Published: January 2024

Seorang ibu setelah melahirkan tidak punya pilihan lain kecuali menyusui bayinya, hal ini juga diyakini oleh budaya yang ada di masyarakat bahwa akan sempurna seorang ibu jika dapat mengandung, melahirkan dan menyusui, akan tetapi kenyataan yang terjadi di masyarakat pemberian air susu ibu (ASI) melalui proses menyusui bukan pilihan satu-satunya bahwa makanan utama untuk bayi baru lahir hanyalah air susu ibu sampai bayi mencapai usia 6 bulan, dan dilanjutkan sampai usia 2 tahun dengan bantuan makanan pendamping ASI. Fenomena yang banyak terjadi yaitu walaupun ibu menyusui bayinya tetapi bayi juga diberikan makanan atau minuman selain ASI. Tujuan penelitian ini yaitu diketahui hubungan karakteristik ibu, kondisi ibu dan bayi serta dukungan dengan pengetahuan tentang pemberian ASI secara Eksklusif pada ibu bayi 6-12 bulan di Kecamatan Tanantovea Kabupaten Donggala. Jenis penelitian ini yaitu penelitian kuantitatif dengan metode survey analitik. Populasi adalah semua ibu yang memiliki bayi> 6-12 bulan. Jumlah sampel semua populasi 96 orang. Data dikumpulkan menggunakan kuesioner. Data dianalisis dengan analisis univariat distribusi frekuensi, dan analisis bivariat kai kuadrat. Hasil penelitian ditemukan: 67 % responden mempunyai pengetahuan cukup tentang ASI. Hasil uji statistik didapatkan 3 variabel yang berhubungan secara signifikan dengan pengetahuan yaitu umur dengan p value = 0.020 (α=0.05), jarak kelahiran antar anak dengan pengetahuan p value = 0.004 (α=0.05), dan kondisi bayi saat lahir dengan pengetahuan p value = 0.025 (α=0.05). Kesimpulan ditemukan ada hubungan antara umur ibu, jarak kelahiran antar anak dan kondisi bayi saat lahir dengan pengetahuan komprehensif ibu lebih dari 6-12 bulan. Saran kepada petugas kesehatan untuk meningkatkan peningkatan pemahaman masyarakat (ibu, suami, keluarga dan masyarakat umum) tentang ASI agar saling mendukung dalam mensukseskan program pencapaian ASI eksklusif.
Hubungan Pengetahuan dengan Perilaku Diet Hipertensi
Authors: Fitriani  , Titi Iswanti Afelya  , Syahrani Hikmatullah Syam  , Dg Mangemba
Published: January 2024

Introduction: Behavior is an important component of individual success in improving their health status. Dietary behavior for hypertensive patients is one of the efforts recommended by health workers to stabilize blood pressure. Knowledge is very influential on hypertensive patients in carrying out dietary compliance. Objective: To determine the relationship between knowledge and hypertension diet behavior. Methods: Descriptive research type, correlation method with cross sectional approach. The study population was hypertensive patients with a total sample of 83 selected by purposive sampling technique. Data collection using a questionnaire. Results: The results showed that there was a relationship between knowledge and hypertension diet behavior with a p-value of 0.006. Conclusion: There is a relationship between knowledge and hypertension diet behavior. The research suggestion is that further research be carried out to discuss hypertensive diet behavior in more depth with observation.
Effectiveness of pharmacotherapies for diabetes on nicotine, food, and water intake in insulin-resistant rats
Authors: Ortegon Sebastian , Giner Priscilla , Cruz Bryan , Carcoba Luis M. , Clapp Benjamin , Clegg Deborah J. , O’Dell Laura E.
Published: January 2024

The intersectionality between diabetes medications and nicotine consumption was assessed in female and male rats. Briefly, the rats were fed a high-fat diet (HFD) or regular diet (RD) for 4 weeks. Then separate groups received vehicle or a low dose of streptozotocin (STZ; 25 mg/kg). Three days later, insulin resistance was assessed by measuring plasma glucose levels for 180 min following an injection of insulin (0.75 U/kg). The rats were then prepared with jugular catheters, and they were given 23 h access to nicotine intravenous self-administration (IVSA) in 4 days cycles with 3 days of forced abstinence in their home cages where they consumed their respective diet. During the IVSA sessions, operant responses for food and water and changes in body weight were recorded. Prior to administration of the pharmacotherapies, the rats were given access to two doses of nicotine (0.015 then 0.03 mg/kg for the remainder of the study). Then, daily injections of the pharmacotherapies were given at the onset of dark cycle (6 p.m.) in the following order: 1) dapagliflozin (3.0 then 10.0 mg/kg), 2) insulin (0.75 U/kg twice), and 3) bromocriptine (3.0 then 10.0 mg/kg). The results suggest that our HFD+STZ regiment induced insulin resistance in female and male rats. Also, the HFD-fed rats displayed higher nicotine intake than RD controls, regardless of sex. Administration of insulin, but not dapagliflozin or bromocriptine, normalized nicotine intake in HFD-fed rats to control levels. These results have clinical implications regarding the potential efficacy of insulin to control excessive nicotine intake in persons with diabetes.
Investigation of laser-induced contamination on dielectric thin films in MHz sub-ps regime
Authors: Stehlik Marek , Zideluns Janis , Petite Camille , Allard Valentin , Minissale Marco , Moreau Antonin , Lereu Aude , Lemarchand Fabien , Wagner Frank , Lumeau Julien , Gallais Laurent
Published: January 2024

High-repetition rate diode-pumped sub-ps lasers are widely used in the industrial sector for high-quality material processing applications. However, for their reliable operation, it is crucial to study the power handling capabilities of the optical components used in these systems. The optical components, such as mirrors, gratings, dichroic filters, and gain media, are designed based on dielectric thin films. When subjected to high-intensity laser radiation, the phenomenon of laser-induced contamination (LIC) can lead to the growth of a nanometric, highly absorbent layer on an irradiated optical surface, which can result in transmission or reflection loss and eventual permanent damage. In this study, we investigate LIC growth on dielectric oxide thin films in an air environment irradiated by MHz sub-ps laser at 515 nm. We examine the effect of thin film deposition method, material, and thickness on LIC growth dynamics. The irradiated spots on the surface are inspected using multiple observation methods, including white light interference microscopy and fluorescence imaging. Our results show that the LIC growth dynamics depend on the laser intensity and irradiation time and can be affected by the thin film deposition method, material, and thickness. These findings could be used to inform the development of more resistant optical components, ensuring long-term reliable laser operation required for industrial applications. The study highlights the need for validating optical components using tests that closely mimic real-world applications and provides insight into the complex processes that lead to LIC.
Case report: Lingual dystonia symptoms treated with botulinum toxin in patients with THAP1 mutation
Authors: Wagle Shukla Aparna , Herndon Nicole , Malaty Irene
Published: January 2024

Background: THAP1 mutation dystonia is a known genetic cause of generalized dystonia. THAP1 mutation frequently presents with clinical features of bulbar dysfunction, including oromandibular and lingual dystonia. Patients complain of significant speech, chewing, and swallowing difficulties leading to major occupational and social disabilities. While bilateral globus pallidus internus deep brain stimulation (DBS) is powerful therapy for generalized dystonia and improves dystonia symptoms in the cervical and limb region, it may not improve speech despite multiple adjustments to the stimulation parameters. Treating lingual dystonia symptoms with oral medications is commonly unsatisfactory. Botulinum toxin injection, a potent therapy for focal forms of dystonia is currently underutilized in clinical practice for treating lingual dystonia.

Cases: We present two patients with THAP1 mutation reporting lingual dystonia symptoms. The first patient did not meet the eligibility criteria for DBS therapy due to significant psychiatric symptoms. The second patient received DBS with improvements in cervical, limb, and trunk symptoms but complained of severe speech difficulties that did not improve despite multiple programming sessions. These patients were treated with botulinum toxin injections every 12 weeks for more than 3 years, with speech improvements lasting most of the cycle. For the most part they tolerated botulinum toxin without bothersome side effects. Along with the clinical histories, we present objective perceptual analysis of speech samples collected before and after botulinum toxin injections in one of the treatment cycles.

Conclusion: Botulinum toxin injections that are clinically beneficial for mitigating lingual dystonia symptoms should be utilized to address symptoms of THAP1 mutation dystonia that may not be amenable to other therapies, such as the DBS.
Concurrent activation potentiation improves lower-limb maximal strength but not dynamic balance control in rugby players
Authors: Rizzato Alex , Dalla Costa Vittorio G. , Bozzato Matteo , Paoli Antonio , Marcolin Giuseppe
Published: January 2024

Concurrent activation potentiation (CAP) increases athletic performance by activating muscles not involved in the performed activity. Among the CAP strategies, jaw clenching is the most practical to implement in sports contexts. Muscle strength and balance control are essential among rugby players to cope tackles. Besides combat sports, mouthguard has become mandatory also in rugby. Therefore, this study aimed to understand whether mouthguard jaw-clenching could improve rugby players’ dynamic balance and quadriceps isometric strength. Thirteen rugby players were tested under maximal-bite (MB) and no-bite (NB) conditions. During standing balance tests, an electro-actuated platform with a force plate screwed on it allowed for the perturbation of the support base of the rugby players. A verbal signal warned the subject that the perturbation was coming, mentally recalling an in-field expected collision. In the first 2.5 s window after the perturbation, the center of pressure (CoP) displacement and mean velocity were measured. The first peak, the maximal oscillations, and the standard deviation of the anterior-posterior CoP trajectory were calculated within the same time window. In the isometric leg-extension test, a custom-built chair instrumented with a uni-axial load cell allowed to collect the maximal strength and rate of force development (RFD). Mouthguard jaw-clenching did not affect CoP-related parameters but increased maximal strength (p< 0.05) and RFD (0–50 ms:p< 0.01; 50–100 ms:p< 0.001; 100–150 ms:p< 0.05) in the isometric leg-extension test. Mouthguard jaw-clenching alone could be useful to increase lower-limb maximal isometric strength and RFD but did not improve dynamic balance performance in a sport-oriented postural balance test.
Systematic review and meta-analysis of the antioxidant capacity of lycopene in the treatment of periodontal disease
Authors: López-Valverde Nansi , López-Valverde Antonio , Macedo de Sousa Bruno , Blanco Rueda José Antonio
Published: January 2024

This systematic review with meta-analysis evaluated the antioxidant effect of lycopene as an adjuvant treatment for periodontal disease. PubMed, EMBASE and Web of Science databases were consulted. According to the PICOs strategy, inclusion criteria were established for intervention studies Randomized Controlled Trials in Probing depth subjects (participants) treated with conventional treatment and lycopene (intervention) compared to patients treated with conventional treatment (control) in which periodontal response to treatment (outcome) was assessed. The risk of bias for randomized studies was assessed using the Cochrane Risk of Bias Tool. The methodological quality of the studies included in the meta-analysis was measured using the Jadad scale. Quantitative data were analyzed using six random-effects meta-analyses, taking into account periodontal parameters: Probing Pocket Depth, Clinical Attachment Loss, Bleeding on Probing, Plaque Index, Uric Acid and Gingival Index. Six further meta-analyses were performed, according to the follow-up of the studies (short-, medium- and long-term). Of the 339 studies identified, only 7 met the eligibility criteria. The meta-analysis of the studies according to the parameters evaluated only obtained statistical significance in the assessment of plaque index (p = 0.003). Regarding follow-up periods, PPD was significant (p = 0.03) in the short term. bleeding on probing estimates were significant in the short and medium term (p = 0.008 and p = 0.03, respectively), IP was significant in the short and medium term (p = 0.0003 and p = 0.01, respectively) and gingival index in the short and medium term (p = 0.002 and p = 0.02, respectively). Heterogeneity was high (I2 >50%) in all assessments, except for Clinical Attachment Loss (I2 = 16.7%). The results demonstrate that antioxidant treatment with lycopene could be useful as an adjunctive treatment for periodontal disease.
Racial disparities in receipt of survivorship care plans among female cancer survivors in Maryland
Authors: Jin Mu , Jones Miranda R. , Connor Avonne E.
Published: January 2024

Background

With the increasing number of cancer survivors in the US, survivorship care plans (SCP) have been promoted to improve survivorship outcomes for cancer patients. Few studies have assessed if the receipt of SCPs differs by race/ethnicity. This study evaluated if racial/ethnic disparities exist in SCP receipt among female cancer survivors living in Maryland.

Methods

Survey data were analyzed for 1,353 non-Hispanic white (NHW) and 280 non-Hispanic Black (NHB) women with a self-reported history of cancer living in Maryland who completed the Maryland Behavioral Risk Factor Surveillance Survey (BRFSS) between 2011 and 2020. Multivariable logistic regression models were used to estimate prevalence odds ratios (PORs) and 95% confidence intervals (CI) for SCP receipt by race/ethnicity. Models were further stratified by demographic, cancer-related, and lifestyle factors to examine effect modification.

Results

On average, survivors were 66.8 years of age at time of BRFSS survey and 53.5 years of age at time of cancer diagnosis. Compared with NHW survivors, NHB survivors reported higher odds of receiving a summary of cancer treatments (POR = 3.81, 95% CI: 2.27, 6.39), instructions from a doctor for follow-up check-ups (POR = 2.10, 95% CI: 1.00, 4.39), and written or printed instructions (POR = 4.74, 95% CI: 2.12, 10.61). Age at survey (<65 years vs. ≥65 years) (p-interaction term = 0.01) and income level (≤50k vs. >50k) (p-interaction term = 0.04) significantly modified the relationship between race/ethnicity and receiving SCPs.

Conclusion

Our findings indicate that NHB female cancer survivors in Maryland are more likely to receive SCP information compared to NHW survivors and this association is significantly modified by age at survey and income level. More research is needed at the patient-provider level to gain a better understanding of the impact of SCP delivery to minority cancer populations.