bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Service Quality, Product Quality, Customer Satisfaction as Mediating Variable and Purchasing Decision on Pempek Ny Kamto Majapahit Semarang Restaurant
Authors: Ariefiantoro Teguh , Suryawardana Edy , Niati Asih
Published: January 2024

How the consequences of Service Quality, Product Quality, Consumer Loyalty as a Mediating Variable to Consumer Loyalty to purchasing decisions in Pempek Ny Kamto Majapahit Semarang. Respondents wore non-random sampling illustration methods. This illustration is wearing Purposive Sampling method, minimun once tasted Pempek Ny Kamto Semarang and the last time had arrived at Pempek Ny Kamto Majapahit Semarang. Methods of collecting information by wearing questionnaires and have been tested for validity and reliability. In testing variable Service Quality, Product quality, Consumer satisfaction with research Purchasing Decisions using multiple linear regression analysis. There are also results showing if Qualiy Service, Product Quality, Consumer Loyalty have a positive and significant influence on purchasing decisions.

 
Build Learning Achievement Through Increased Student Learning Motivation
Authors: Yuliati Etik , Istiatin Istiatin , Sudarwati Sudarwati
Published: January 2024

The aims of this study were to examine and analyze the effect of motivation, discipline, parental background, and the use of gadgets together on student achievement in SMK Negeri 1 Sragen.  The research was conducted for 6 months, starting from March to August 2021 by taking the location at SMK Negeri 1 Sragen. The population in this study was class XII students with a total of 500, while the sample used was students with top ten rankings in each class with a total of 140. In this study the data used by researchers were (1) primary data, (2) secondary data. Data collection techniques were carried out through observation, interviews, documentation, questionnaires, and literature studies. The data processing technique was carried out using the SPSS program to test the instrument (validity test and reliability test), linear regression test, classical assumption test (normality test, heteroscedasticity test, and multicollinearity test), determination test (R2), hypothesis test (F test). and t test). The results of this study are based on (1) the F test, the F count is 32.005 while the F table is 2.680, thus hypothesis 1 is tested for truth (2) the t-test on the motivation variable is obtained t-count is 4.703, while the t-table is 1.978, so the second hypothesis is verified (3 ) t test on the discipline variable obtained t count 2,427, while t table 1,978, so the third hypothesis is tested for truth (4) t test for parental background variable obtained t count 2,116, while t table 1,978, so the fourth hypothesis is verified. (5) the t-test of the gadget use variable obtained t-count 3.567, while the t-table was 1.978, so the fifth hypothesis was verified
Effect of Return on Asset, Debt Equity Ratio and Current Ratio on Company Value (Study on Manufacturing Companies Listed on Indonesia Stock Exchange for the Period 2017-2020)
Authors: Noegroho Novianto , Ariefiantoro Teguh , Suryawardana Edy
Published: January 2024

The purpose of this study is to examine the effect of Profitability proxied by ROA, Working Capital Proxied by Debt Equity Ratio and Liquidity Proxied by current Ratio to the potential for Firm Value in the company. The sample used in this study is various manufacturing companies listed on the Indonesia Stock Exchange during the period 2017 to 2020. The sample selection method used was the purposive sampling method. Hypothesis testing is done using logistic regression. Based on the results of hypothesis testing it can be concluded that the Return On Asset variable is proven to have a significant positive effect on the likelihood of Firm Value, the Debt Equity Ratio Variable is proven to have a significant negative effect on the likelihood of Firm Value, as well as the Current Ratio variable also has a significant Positif effect on the likelihood of firm Value.
The Effect of Current Ratio, Return on Equity, And Company Size on Company Value in The Pharmaceutical Sector
Authors: Putri Ika Swasti , Octavia Ayu Nurafni , Fitriani Laili Nur , Bulqis Tiara
Published: January 2024

ABSTRACT

This study aims to determine the effect of the current ratio, return on equity, and firm size on firm value. The population of this study is pharmaceutical sub-sector companies listed on the IDX for the 2017-2021 period. Samples taken using the purposive sampling method resulted in 8 companies and 40 data. The analytical model used in this study is a multiple linear regression model. Data processing and analysis using multiple linear regression analysis using the SPSS version 25 application. The results of this study found that the current ratio, return on equity, and company size did not have a significant effect on firm value in pharmaceutical sub-sector companies listed on the IDX in 2017-2021. 

Keywords: Current Ratio; Return On Equity; Firm Size; Firm Value;
Formulation and organoleptic characteristics of flavor enhancer from shrimp
head protein hydrolysate
Authors: Yuniarti T. , Prayudi A. , Setiarto R.H.B. , Martosuyono P. , Supenti L. , Suhrawardan H. , Maulani A.
Published: January 2024

Protein hydrolysate can be produced from by-products of the fishing industry, such as
shrimp heads. This product is made by enzyme hydrolysis through the breakdown of
shrimp head protein into short-chain peptides and amino acids. Enzymatic hydrolysis
produces protein hydrolysate, which has savory, umami, and water-soluble characteristics.
The savory and umami taste results from the high content of glutamic acid and other free
amino acids. This study aimed to determine the best formulation and organoleptic
characteristics of the shrimp head protein hydrolysate flavor enhancer. Production of
shrimp head protein hydrolysate (SPH) using alkalase enzyme at a temperature of 55°C
with an enzyme concentration of 20,000 units/kg substrate for 7 hrs. Parameters tested
were yield, proximate and amino acid analysis, and organoleptic test for SPH flavor
enhancer. SPH has an amino acid composition dominated by arginine, alanine, glycine,
glutamic acid, leucine and lysine. The flavor enhancer with 40% SPH composition was
chosen as the best formula because it has sensory characteristics close to P0 commercial
flavoring. The dominant sensory attributes were spicy, salty, umami and sweet. Overall,
protein hydrolysate-based flavor enhancers' solubility and color properties are close to
commercial flavor enhancers. The flavor enhancer made from SPH has the potential to be
used as a substitute for commercial flavor enhancers which are rich in essential amino
acids.
Effectiveness of My Alazka Application Learning Media in Improving Student’ Chemistry Learning Outcomes
Authors: Wahjusaputri Sintha , Ramadhani Siti Sarah , Saepudin Asep , Reihan Muhammad , Suryanto Hendi
Published: January 2024

Objective: This research aims to determine, analyze, and identify the effectiveness of the My Alazka Application learning media on the chemistry learning outcomes of 10th grade pupils. Method: This study used a quantitative method for experimental research. The subject of this study was a 28 Student in 10th grade, in accordance to the pretest-posttest design with a single group. This research uses instruments such as questionnaires that are used once before the investigation, known as the pre-test, and once after the experiment, known as the post-test. Result: Based on the Descriptive N-Gain Score data output, The data indicates the mean N-Gain score among students in 10th grade is 63.3074 or 0.63 which is included in the "moderate".  The use of My Alazka can significantly enhance the effectiveness of the learning process in communicating messages and lesson content, also learning outcomes of chemistry subjects for student in 10th grade. Novelty: My Alazka application can be an alternative solution for educators and students during the implementation of the learning processes to improve chemistry learning outcomes for 10th grade student.
Cultivares de Palma Forrageira sob Diferentes Arranjos e Densidades de Plantio
Authors: De Sá Teles Eudo Barreto , Arantes Alessandro de Magalhães , Rodrigues Donato Sérgio Luiz , Soares Rômulo Souza , Da Silva João Abel , Rodrigues Donato Paulo Emílio
Published: January 2024

A palma forrageira tem se destacado na região semiárida brasileira com a principal função de suporte forrageiro para a alimentação animal no período de estiagem. Dessa forma, objetivou-se com o presente estudo avaliar o desempenho das cultivares de palma forrageira Orelha de Elefante Mexicana (Opuntia stricta (Haworth) Haworth) e Gigante (Opuntia fícus-indica Mill), sob diferentes configurações e densidades de plantio. Os 12 tratamentos foram dispostos num delineamento em blocos casualizados, em esquema de parcelas subsubdivididas, com três repetições. As parcelas foram constituídas por duas configurações de plantio (CP), fileira simples e fileiras triplas; as subparcelas compostas por duas cultivares (Cv), Gigante e Orelha de Elefante Mexicana; e as subsubparcelas por três densidades de plantio (DP), 20, 40 e 60 mil plantas ha-1. As variáveis avaliadas foram: altura (AP) e largura (LP) da planta, comprimento (CC), largura (LC) e espessura do cladódio (EC), número de cladódio (NC), índice de área de cladódio (IAC) e produtividade de matéria verde (PME). As mensurações foram realizadas a cada 60 dias, a partir dos 90 até os 510 dias após o plantio. A densidade de plantio com 60 mil plantas ha-1 e a configuração de plantio em fileira tripla, promoveram maior produtividade da palma forrageira. A cultivar Orelha de Elefante Mexicana apresentou nas condições desse experimento produtividade superior a Gigante.
¿La Teoría del Comportamiento Planeado y la prevalencia percibida predicen la Deshonestidad Académica?
Authors: Reskala Felix
Published: January 2024

La deshonestidad académica se asocia con corrupción general, acciones laborales deshonestas, y la mala reputación escolar. Sin embargo, pocos artículos han estudiado el rol de la prevalencia percibida de la trampa escolar. Por lo tanto, utilizando la Teoría del Comportamiento Planeado, y la prevalencia percibida, este artículo propone un modelo de ecuaciones estructurales para explicar las acciones de deshonestidad académica. Por medio de cuestionarios se midieron las siguientes variables: Prevalencia percibida de la trampa escolar, deshonestidad académica auto reportada, y las variables del TCP (intención, actitudes, norma subjetiva, control conductual percibido, y obligación moral). Los resultados muestran que las actitudes y la obligación moral de la TCP son predictores significativos de la deshonestidad académica, mientras que la prevalencia percibida es un mediador relevante. Estos resultados muestran que la prevalencia percibida, las actitudes, y obligación moral deberían de incluirse en las intervenciones futuras que busquen reducir la deshonestidad académica.
ANALISIS RESIKO NILAI EKONOMI DAN PRODUKSI USAHATANI PADI SAWAH DI DESA PUNDEN REJO KECAMATAN TANJUNG MORAWA
Authors: Tanjung Ade Firmansyah , Kembaren Emmia Tambarta , Fadli Fadli , Barmawi Barmawi , Nurhajijah Nurhajijah
Published: January 2024

Realizing the welfare of farmers starts with increasing the economic value and feasibility of the income received in accordance with the needs of the farmer's household. The hope is that the economic value obtained from farming is still at the limit of a low level of farming risk. Implementation of the research location in Punden Rejo Village. For primary data processing, questionnaires and interviews were conducted with 30 farmers. For the determination of respondents conducted by disproportionate stratified random sampling method. To calculate the level of risk of economic value of farming can use variance analysis (Variance) and standard deviation (standard deviation). After calculating the value of variance and standard deviation, then the next step is to calculate the coefficient of variation (CV). Based on the results of research conducted from data from interviews and observations at the research location, for risk analysis of the economic value of farming based on the calculation of the coefficient of variation (CV) less than 0.5 (0.23 < 0.5) and risk analysis of production value based on the calculation of the coefficient of variation (CV) less than 0.5 (0.22 < 0.5).
Analisis Faktor-faktor yang Mempengaruhi Produksi Cabai Rawit di Kecamatan Kediri Kabupaten Lombok Barat
Authors: Febrilia Baiq Rika Ayu , Sari Ni Made Wirastika , Danasari Idiatul Fitri , Vijaya Ni Putu Sephia Ananda
Published: January 2024

Cayenne pepper is a leading commodity in Indonesia. Therefore, the amount of cayenne pepper production needs to be studied properly, including how to optimize its production through the factors that affect the amount of production. This study aims to analyze the factors that influence the amount of cayenne pepper production in Kuripan District, West Lombok Regency. The method used in this research is descriptive method involving 30 respondents. Data is collected through direct survey method. Data analysis was performed using descriptive analysis and multiple linear regression analysis. The data collected was in the form of the amount of cayenne pepper production, the area of cultivated land, the length of farming experience, the number of workers owned, the number of family members supported, the number of seeds and the amount of fertilizer used. The results showed that the six factors used, namely arable land area, length of farming experience, a lot of labor owned, a lot of dependants, a lot of seeds and a lot of fertilizer simultaneously affect the amount of cayenne pepper production. The factors that partially influence the amount of cayenne pepper production are the area of arable land and the number of family dependents.
ANALISIS KELAYAKAN USAHA BAKPIA KACANG HIJAU PADA UMKM C’BAKPIA DI KECAMATAN SUMBERBARU KABUPATEN JEMBER
Authors: Silviani Silviani , Artiani Nanda Ayu , Maharani Fadillah
Published: January 2024

Agroindustri merupakan suatu industri yang melakukan pengolahan hasil dari sektor pertanian menjadi suatu produk yang dapat menghasilkan nilai. Salah satu agroindustri UMKM yang mengolah kacang untuk dijadikan olahan kue bakpia yaitu C’Bakpia. Kabupaten Jember sendiri produsen kue bakpia cukup banyak, sehingga menjadi masalah tersendiri untuk memasarkan produknya. Dengan demikian, diperlukan adanya analisis kelayakan pada UMKM C’Bakpia  apakah layak atau tidak untuk dilanjutkan. Metode penelitian yang dipakai menggunakan metode wawancara dan observasi. Berdasarkan hasil penelitian diperoleh bahwa UMKM C’Bakpia layak untuk diusahakan. Hal tersebut bisa dilihat berdasarkan hasil perhitungan R/C Ratio, B/C Ratio, dan BEP yang memenuhi kriteria pengambilan keputusan yakni R/C Ratio diperoleh hasil 1,52 (1,52 > 1), B/C Ratio diperoleh hasil 0,52 (0,52 > 0), BEP unit diperoleh hasil 10.253 unit/tahun dan BEP harga diperoleh hasil Rp. 111.905.034/tahun.
ANALISIS PENDAPATAN USAHA PETERNAKAN AYAM KAMPUNG DI KECAMATAN PULAU PUNJUNG KABUPATEN DHARMASRAYA (Studi Kasus: Tigo Putra Farmer)
Authors: Novarista Noni , Jarlis Roni , Marna Tilta
Published: January 2024

Penelitian ini bertujuan untuk mengetahui besar pendapatan usaha peternakan ayam kampung pada Tigo Putra Farmer. Penelitian ini dilaksanakan pada bulan Juli 2021-April 2022. Metode penelitian yang digunakan adalah metode studi kasus. Data yang digunakan terdiri dari data primer dan sekunder. Data primer diperoleh secara langsung dari hasil wawancara dengan responden, pengamatan secara langsung di lokasi penelitian dan dokumentasi data berupa gambar. Data sekunder merupakan data tidak langsung yang diperoleh dari BPS, jurnal dan buku literatur. Metode analisis data yang digunakan adalah analisis deskriptif kualitatif dan kuantitatif. Dari hasil penelitian diketahui bahwa Biaya produksi Usaha Peternakan Tigo Putra Farmer, yaitu sebesar Rp.61.467.300,-. Penerimaan sebesar Rp.105.600.000,-. Pendapatan sebesar Rp.44.132.700,-. Keuntungan sebesar Rp.6.132.700,- dan R/C Ratio sebesar 1,71. Hal ini menunjukan bahwa Usaha Peternakan Tigo Putra Farmer mengalami keuntungan, karena R/C Ratio > 1 maka usaha ini layak untuk dijalankan.
TI Rutas de la Inserción Laboral del egresado de la Facultad de Administración y Contaduría de la U A de C
Authors: Alanís-Gómez C Lilia , Buentello-Martínez Clara Patricia , Valenzuela-Salazar Nemecio Lorenzo
Published: January 2024

El incremento de nuevas empresas es hoy día una forma más de promover la inserción laboral de los recién egresados, una de las cuestiones más importantes a resolver es que los alumnos egresen con una preparación óptima para que se puedan desempeñar en el campo laboral adecuadamente. Es importante que los estudiantes tengan un perfil de egreso como guía de las cualidades que deben de cumplir según el mercado laboral actual lo que permite unificar criterios para establecer rutas para el logro de los objetivos de la Facultad de Administración y Contaduría el cuál es que los estudiantes egresen con las aptitudes y habilidades para enfrentar los retos de un Lic. en Contaduría. El estudio se fundamenta en una investigación mixta ya que los datos se recogen en la empresa donde se desarrolló la investigación. Los alumnos de la FAC consideran que lo que se le ha impartido cumple con los objetivos de la carrera, así como también el hecho de que ellos consideran que al egresar ellos cumplirán con el perfil establecido.
Transferencia de tecnología universidad-industria y el sistema de innovación en México
Authors: Calderón-Altamirano Elisa , Castro-Coria Eva
Published: January 2024

Mediante una revisión sistemática de literatura respeto de la transferencia de tecnología universidad-industria de Estados Unidos, Canadá y México, específicamente las patentes universitarias vinculadas al desarrollo económico de estos países, se desprendió la necesidad de que el sistema de innovación en México se fortalezca mediante la explotación, producción y difusión del conocimiento, requisitos indispensables para el crecimiento y desarrollo tanto de su comunidad académica como del sector empresarial. De la revisión se desprende que la generación y transferencia de conocimiento al ámbito comercial, es decir, de universidades a empresas, mediante mecanismos de licencia, contribuyeron potencialmente a generar ingresos, así como establecer relaciones con actores externos y mejorar el crecimiento y el desarrollo en la región.
Investigation of Mechanical Properties of Ti6Al4V Alloy Foams produced by Powder Metallurgy Method
Authors: TOPCU İsmail
Published: January 2024

In this study, it was aimed to production titanium alloy implants, which are widely used in the biomedical industry, as foamed materials under different mechanical alloying and sintering conditions using the powder metallurgy method Tİ6Al4V alloy is good mechanical properties, good biocompatibility properties and good corrosion resistance used as hard tissue replacements and implants. Similar mechanic properties with bone are expected from the implant to work coherently for long cycles of use and without any failure. Especially, elastic modulus of implant must be similar with bones, if not, some damages at bone surface and fallowing repeats of implant surgeries are reported. This situation has a destructive effect on health, finance, and comfort of the patient/user of the implant. In this study, powder metallurgy and space holder removal methods were used to produce porous Ti6Al4V specimens. Throughout the project study different space holder materials and binder agents were used. As weight percent, 20%, 30%, 40%, 60%, 70%, 80% porous specimens were pressed at uniaxial press machine, and sintered to the 850 ºC at argon atmosphere in furnace to reduce the oxidation to the level as low as possible. The E-Modulus values of the specimens reached the desired values with increasing porosity. It was obtained as 88 MPa in the specimen with 80% porosity, decreasing inversely proportionally, especially from the 60% porosity rate.
Üretim Parametrelerinin Seçici Lazer Ergitme Yöntemi ile Ti6Al4V Alaşımının Çekme Dayanımı, Elastisite Modülü ve Uzama Özelliklerine Etkisi
Authors: AYDIN Dilara Selma , YILDIRIM Çağrı Vakkas , ŞİRİN Şenol
Published: January 2024

Eklemeli imalat, bilgisayar kontrollü üç boyutlu katı model verilerini kullanan modern bir imalat yöntemidir. Eklemeli imalatta amaç; malzemeyi kademeli şekilde üreterek nihai şekline getirmektir. Bu sayede karmaşık geometrilere sahip ürünlerin elde edilmesi diğer klasik yöntemlere göre nispeten daha kolaydır. Özellikle, yüksek ölçüm doğruluğuna, yüksek dayanıma ve düşük ağırlığa sahip parçaların hızlı üretilmesinin gerekli olduğu havacılık-uzay endüstrisi, biyomedikal ve savunma sanayii gibi geniş bir alanda tercih edilmektedir. Eklemeli imalat birçok alt yöntemden oluşmakta ve bu yöntemler malzemenin cinsi, parçanın boyutu, kullanım amacı, çalışma prensibi, malzemelerin hassasiyeti ve özellikleri, üretim sayısı ve hızı gibi birçok kritere bağlıdır. Seçici lazer eritme (SLM) yöntemi, eklemeli imalat yöntemleri arasında genellikle tercih edilmektedir. Ancak, SLM prosesini doğrudan ve dolaylı parametreler olmak üzere birçok faktör etkileyebilmektedir. Bu çalışmanın amacı, farklı üretim parametrelerinin SLM yöntemi kullanılarak üretilen Ti6Al4V alaşım malzemesi üzerinde mekanik özelliklerine etkisini incelemektir. Bu amaç doğrultusunda dört farklı üretim parametresi ve seviyeleri üretim parametresi olarak belirlenmiştir. Değerlendirme kriteri olarak çekme dayanımı, elastisite modülü ve uzama yüzdesi seçilmiştir. Deney tasarımında Taguchi L16 tercih edilmiştir. Deney sonuçları değerlendirilirken S/N analizi kullanılmıştır. Kontrol faktörlerin etki düzeyini belirlemek için varyans analizi (ANOVA) yapılmıştır. Deney sonuçlarından elde edilen verilerle çekme dayanımı için optimum parametreler; 75 μm lazer odak çapı, 230 W lazer gücü, 60 μm tarama mesafesi ve 300 mm/sn hız tarama hızı olarak tespit edilirken, elastisite modülü için 60 μm tarama mesafesi, 450 mm/sn tarama hızı, 80 μm lazer odak çapı ve 250 W lazer gücü ve uzama miktarı için 90 μm lazer odak çapı, 150 μm tarama mesafesi, 450 mm/sn tarama hızı ve 230 W lazer gücü olarak tespit edilmiştir.
Bakır Oksit-Su ve Elmas-Su Nanoakışkanlı Birleşik Jet Akışlı Kanallarda Isı Transferi ve Akış Yapılarının Değerlendirilmesi
Authors: KARABULUT Koray
Published: January 2024

Bu çalışmada, sabit 1000 W/m2 ısı akısına sahip dairesel oyuklu ve yamuk modelli bakır plakalı yüzeylerden olan ısı transferi ve birleşik jet akışlı kanallardaki akış yapıları su, %2 hacimsel konsantrasyonlu CuO-Su (Bakır oksit)-Su ve Elmas-Su nanoakışkanları kullanılarak sayısal olarak incelenmiştir. Sayısal çalışma, sürekli ve üç boyutlu olarak k-ε türbülans modelli Ansys-Fluent programının kullanılmasıyla gerçekleştirilmiştir. Kanallara ayrıca jet girişinden itibaren D jet giriş çapı ölçüsündeki sabit bir uzaklıkta (N) 45o ve 90o açılı kanatçıklar eklenmiştir. Kanal yüksekliği 3D iken; akışkanların Re sayısı aralığı 5000-15000’ dir. Çalışmadan elde edilen sonuçların doğruluğu ve kabul edilebilirliği deneysel araştırmalar sonucu elde edilen eşitlik kullanılarak kanıtlanmıştır. Çalışmanın sonuçları, kanallardaki her bir model için ortalama Nu sayısının değişimleri olarak su ve nanoakışkanlar için kanatçıksız ve kanatçıklı durumlarda karşılaştırmalı olarak değerlendirilmiştir. Ayrıca, CuO-Su nanoakışkanı için birleşik jet akışın hız ve sıcaklık konturu dağılımları farklı kanatçık açıları için sunulmuştur. Bununla birlikte, kanallardaki her üç desenli yüzeyin tümü için farklı Reynolds sayılarında performans değerlendirme sayıları (PEC) ve ortalama Nu sayısı (Num) ve yüzey sıcaklık değerleri (Tm) Re=5000 ve 15000 için analiz edilmiştir. Re=15000 için 90o kanatçıklı kanalda yamuk modelli yüzeyde sırasıyla Elmas-Su ve Bakır oksit-Su nanoakışkanları kullanılması durumları için kanatçıksız ve su akışkanı kullanılan kanallara göre Num sayısında %27,57 ve %26,11’ lik artışlar elde edilmiştir. Bunun yanı sıra, Re=15000 değerinde 90o açılı kanatçıklı kanallarda su akışkanı için PEC sayısı değerlerinin sırasıyla dairesel oyuklu ve yamuk modelli yüzeylerde Elmas-Su ve CuO-Su nanoakışkanlarına göre %1,1-%1,31 ve %0,82-%0,63 daha fazla oldukları tespit edilmiştir.
Cam Küre Takviyeli Polimer Kompozitlerde UV Yaşlandırma ve Uyumlaştırıcı Etkisinin İncelenmesi
Authors: ULUTAŞ Elif , TAŞDEMİR Münir
Published: January 2024

Maleik anhidrit aşılı polipropilen (MAPP) oranı ve UV (Ultraviyole) yaşlandırma işleminin polipropilen (PP)/cam küreler (GS) polimer kompozitlerinin mekanik ve morfolojik özellikleri üzerindeki etkileri üzerine bir araştırma yapılmıştır. UV yaşlandırma, 70 C sıcaklıkta 0, 15, 30 gün olacak şekilde üç farklı bekletme süresinde gerçekleştirilmiştir. Polipropilen matris içerisine %1, 5, 10 ve 15 oranlarında katılan cam küre parçacıkları ekstrüderde karıştırılarak homojen bir karışım elde edilmiştir. Ekstrüderde elde edilen karışım kırıcıdan geçirilerek granül formuna getirilmiştir, ardından enjeksiyon makinesinde standartlara uygun şekilde test numuneleri kalıplanmıştır. MAPP ve UV tutma süresinin, PP/cam küreler kompozitlerinin elastik modülü, akma mukavemeti, kopmadaki çekme mukavemetleri, %uzama, İzod darbe mukavemeti, sertlik, yoğunluk ve morfolojik özelliklerine etkileri araştırılmıştır. MAPP ve UV tutma süresinin, kompozitlerin elastiklik modülü ve yoğunluğu gibi mekanik özellikleri üzerinde marjinal etkileri vardır. Sonuçlar, artan MAPP içeriğinin ve UV tutma süresinin elastiklik modülü ve yoğunluğunun artmasına neden olduğunu, buna karşın UV tutma süresi arttıkça İzod darbe dayanımı ve %uzamanın azaldığını göstermiştir. MAPP içeriği kompozitin termal davranışına etki ederek vicat yumuşama sıcaklığı ve ısıl çarpılma sıcaklığı-HDT değerlerinde önemli derecede artışa sebep olmuştur. Ayrıca, bu deneylerde cam küre parçacıklarının mikro yapısını ve malzeme dağılımını değerlendirmek için taramalı elektron mikroskobu (SEM) incelemesi yapılmıştır.
Doğu Karadeniz Bölgesi Doğal Taşlarının Beton Üretiminde Agrega Olarak Kullanılabilirliğinin İncelenmesi
Authors: KOÇ Ercüment , YILMAZ Tekin , YILMAZ Ali Osman
Published: January 2024

Agrega, inşaat endüstrisinin en önemli yapı malzemelerinden birisi olan beton içerisinde oldukça yüksek miktarda (%65-80) bulunur. Bu bağlamda, bu çalışma, Doğu Karadeniz Bölgesi’nin farklı lokasyonlarından getirilen doğal taşların (andezit, bazalt, çamurtaşı ve traverten) beton üretiminde agrega olarak kullanılabilirliklerinin araştırılması üzerine kurgulanmıştır. Bu amaçla, farklı numune şekillerinde (silindirik karot, küp ve kırılmış agrega) hazırlanan doğal taş numuneleri üzerinde bazı fiziksel ve mekanik testler gerçekleştirilmiş ve testlerden elde edilen bulgular TS 706 EN 12620+A1 (2009) tarafından belirlenen agrega standartları açısından değerlendirilmiştir. Bulgular, fiziksel ve mekanik özellikler açısından en yüksek performansı sağlayan bazalt kayacının beton agregası olarak kullanımının uygun olduğunu göstermiştir.
Geleceğin Alternatif Protein Kaynakları: Bitkiler
Authors: SEYHAN Selen , NAKİLCİOĞLU Emine , ÖTLEŞ Semih
Published: January 2024

Proteinler, aminoasitler tarafından oluşturulan azot içerikli bir besin maddesidir. Vücudumuzda birçok fonksiyona hizmet eden proteinler, sağlıklı bir yaşam için gereklidir. Gün geçtikçe artan dünya nüfusu nedeniyle gıda endüstrisinde bitkisel protein kaynaklarına yönelim hız kazanmıştır. Tüketicilerin hayvansal proteinlere ulaşmasında, artan maliyetler ve sınırlı tedarikler nedenleriyle büyük sıkıntılar çıkabilmektedir. Ayrıca bilinçsiz hayvansal ürün tüketiminin birçok sağlık sorununa neden olduğu bilinmektedir. Çölyak hastalığı veya gluten duyarlılığı gibi sağlık sorunları, bireylerin sağlıklı beslenme yönündeki eğilimleri ve vegan, vejetaryen gibi beslenme tarzları ile bitkisel kaynaklar değer kazanmaktadır. Son zamanlarda bitkisel proteinler, insan beslenmesinde hayvansal kaynağın yanı sıra ürün formülasyonu için fonksiyonel bileşenlerin yerini alan ekonomik ve çok yönlü bir alternatif olarak daha fazla kullanılmaktadır. Bu derleme, bitkisel protein kaynaklarından yağlı tohumlar, tahıllar ve diğer bitkiler hakkında genel bir bilgi vererek bahsedilen bitkisel protein kaynakları ile ilgili gıda alanında yapılan çalışmaları içermektedir.
Elektromanyetik Radyasyon Maruziyet Algısı Ölçeğinin Geliştirilmesi: Geçerlilik ve Güvenilirlik Analizleri
Authors: ÇEREZCİ Osman , TUTGUN-ÜNAL Aylin , CEREZCİ Feyza
Published: January 2024

Teknolojinin ilerlemesiyle birlikte yeni çevre sorunlarıyla karşılaşmaktayız. Son zamanlarda, duyularımızla fark edemediğimiz, iletişim teknolojilerinin ve elektriğin yaygın kullanımının çevresel bir atığı olan elektromanyetik radyasyonun olumsuz sağlık sonuçları tartışılmaktadır. Elektromanyetik radyasyon seviyesinin oluşturduğu olumsuz etkiler ile alınacak kişisel ve toplumsal önlemler için algı çalışmalarının yapılması gereklilik haline gelmiştir. Bu çalışmada, elektromanyetik radyasyon maruziyet algısı ile önlem almaya yönelik algı seviyesinin boyutsal olarak ölçülebilmesi amacıyla 1187 kişiden oluşan bir çalışma grubunda Elektromanyetik Radyasyon Maruziyet Algısı Ölçeğinin geliştirilmesi amaçlanmıştır. Yapılan geçerlilik ve güvenilirlik çalışmaları sonucunda, 11 madde ve 3 boyuttan (Farkındalık, Bilinçlilik, Endişe) oluşan geçerli ve güvenilir bir ölçek elde edilmiştir. Ölçek toplam varyansın %57,6’sını açıklamıştır. Ayrıca yapılan doğrulayıcı faktör analizi ile elde edilen üç faktörlü ölçek yapısı modellenmiş ve doğrulanmıştır. Elde edilen uyum iyiliği değerleri kabul edilebilir aralıkta bulunmuştur (Ki-kare/serbestlik değeri: 2,94; RMSEA: ,07; NFI: ,91; NNFI: ,92; CFI: ,96; GFI: ,92; AGFI: ,87). Ölçeğin güvenilirlik katsayısı Cronbach Alpha değeri “Farkındalık” boyutu için ,82, “Bilinçlilik” boyutu için ,74, “Endişe” boyutu için ,64 ve ölçek toplamı için ,77 olarak bulunmuştur. Böylece, Elektromanyetik Radyasyon Maruziyet Algısı Ölçeği adında geçerli ve güvenilir bir ölçek ortaya çıkmıştır.
Mantıksal Regresyon, Frekans Oranı ve ArcGIS Pro Suitability Model ile Yalova-Çınarcık Bölgesinin Heyelan Duyarlılık Analizi
Authors: TAŞ Zeliha , CORUK Özkan
Published: January 2024

Bu çalışmada Türkiye’nin batısında yer alan Yalova-Çınarcık bölgesinde, yaklaşık 11 km2 olan inceleme alanında heyelan duyarlılık analizi yapılmıştır. Bölgede geniş yayılımlı 20 heyelan bölgesi incelenmiştir. Mantıksal Regresyon, Frekans Oranı ve ArcGIS Pro Uygunluk Modeli ile heyelan duyarlılık analizi yapılmıştır. Verilerin %80’i analiz, %20’si test için kullanılmıştır. Analizin doğruluğunu test etmek için Alıcı İşletim Karakteristik (Receiver Operating Charasteristic-ROC) eğrisi ve Eğrinin Altında Kalan Alan (Area Under the Curve-AUC) kullanılmıştır. Yapılan analizler sonucunda Mantıksal Regresyon yöntemine göre inceleme alanının %5.41’i çok düşük, %10.32’si düşük, %31,22’si orta, %24,98’i yüksek ve %28,05’i çok yüksek heyelan duyarlılık sınıfındadır ve AUC sonucu ise %78,8’dir. Frekans Oranı için ise inceleme alanının %30,8’i çok düşük, %14,48’i düşük, %4,5’i orta, %24,02’si yüksek ve %26,2’si çok yüksek heyelan duyarlılık sınıfında olup AUC sonucu %64,4’tür. ArcGIS Pro Uygunluk Modeli için ise %4,42’si çok düşük, %20,57’si düşük, %27,9’u orta, %23,42’si yüksek ve %23,67’si çok yüksek ve AUC değeri %69,7’dir. Bu çalışmada elde edilen duyarlılık analizi verileri ile yüksek ve çok yüksek duyarlılık sınıfındaki bölgeler için gerekli önlemlerin ve bölgede yapılacak arazi planlaması için bu sonuçların dikkate alınması önerilmiştir.
Pre-service EFL teachers’ identity construction in relation to digital gamification: A social theory of learning perspective
Authors: Masitoh Fitriatul , Cahyono Bambang Yudi , Suryati Nunung , Suhartoyo Eko
Published: January 2024

Nowadays, digital technology is a vital aspect of teaching. Therefore, it is essential for pre-service teachers of English as a foreign language (EFL) to develop an identity that fits the current needs. In response to this demand, this study aims to explore pre-service EFL teachers’ identities in relation to digital technology, more particularly gamification. This study employs Wenger's social theory of learning especially the Engagement, Imagination, and Alignment modes of belonging. This study involved four pre-service EFL teachers from two different contexts in Indonesia. Data on participants' involvement in digital gamification were collected from the written history records of the participants and semi-structured interviews. Data which were collected during seven-week period of the participants’ teaching practice were analyzed to grasp how digital gamification influenced the development of their identities as pre-service EFL teachers. The findings indicate that the participants encountered identity struggles in using digital gamification to negotiate their identities when teaching practice in placement schools. Likewise, they claim to have developed a number of identities such as contemporary, tech-savvy, innovative, and up-to-date pre-service EFL teachers. The results of this study assert that initial teacher education would benefit from focusing on the identities of pre-service EFL teachers. This implies that pre-service EFL teachers need to continually maintain their ever-changing digital identities and that schools need to provide pre-service EFL teachers with additional technological resources.
The impact of tax expenditures on economic growth: The US experience
Authors: Kakaulina Maria , Kazansky Nikita
Published: January 2024

In the last decade, assessing the tax expenditures’ economic efficiency has grown in importance due to the increasing number of situations where stakeholders use tax benefits for personal enrichment. The problem is aggravated by the very nature of tax expenditures, which represent budget revenue losses. The expediency of tax expenditures can be proved by estimating their impact on economic growth. The paper aims to measure such impact using the case of the USA. Methodologically, the study relies on Barro’s conception of endogenous growth. The study applies econometric methods of analysis. The data for the study is taken from the Global Tax Expenditures Database (GTED), the U.S. Department of the Treasury, the U.S. Bureau of Economic Analysis, and the U.S. Census Bureau for 1998–2022. The results indicate no correlation between the share of tax expenditures in a specific sphere in the total amount and their efficiency (the strength of the positive impact on GDP). For instance, the tax expenditures in commerce and housing have the greatest share (35.4 %), yet their impact is relatively weak compared to other categories of tax expenditures: 1 dollar of expenditures induces a 0.04 dollar increase in GDP. At the same time, tax expenditures in the social sphere with an insubstantial share of 2 % generate a 10 times higher return (a 0.49 dollar increase in GDP per 1 dollar of expenditures). Therefore, the structure of tax expenditures with an explicit social orientation appears to be the most preferable for the USA.
Adherence to endocrine adjuvant therapy in women with early hormone-positive breast cancer
Authors: Suzuki Daniele Assad , Santos Danielle Laperche dos , Galvão Anna Luiza , Oliveira Sulene Cunha Souza , Souza Cristiano de Pádua , Custódio Amanda Guimarães Castro , Barroso-Sousa Romualdo
Published: January 2024

Objective: This study aimed to evaluate adherence to adjuvant endocrine therapy in women with early breast cancer and explore its relationships with patients’ clinical and social characteristics and site of treatment. Methodology: Women with a past history of early-stage estrogen-receptor-positive invasive carcinoma of the breast on adjuvant endocrine therapy for at least 6 months were invited to participate in this study. Adherence was assessed with the questionnaire MMAS8. Demographic and clinical information was reviewed from medical records. Data collection was performed using the RedCap software, and statistical analyses were performed using the R software (R Core Team, 2022). Results: From June 2021 to March 2023, a total of 212 patients were recruited in 6 institutions. The median age was 56 years. Notably, 29.2% were black, 24.1% were premenopause, 38.2% had stage I disease, 65.1% received chemotherapy, and 16.5% received HER2 blockade. The mean duration of endocrine therapy use was 3.7 years. A total of 115 (54.2%) patients used aromatase inhibitors. Notably, 24 (11.4%) patients had low adherence, 76 (36.5%) had intermediate, and 111 (52.6%) had high adherence to adjuvant endocrine therapy. There is a tendency that more postmenopausal women were classified in high adherence grupo than premenopausal women (55.9% vs. 42% p=0.19). There is a tendency that more women in public service had higher adherence than women in private service (59.3% vs. 50.3% p=0.07). There was no difference in adherence in relation to ethnicity and type/duration of endocrine treatment. Conclusion: This study for the first time shows that high adherence to endocrine therapy only happens in 52.6% of patients, lower than reported in previous studies. This result draws attention because it can compromise survival. We will continue the recruitment of patients in the private service and in the public service to assess the rate of adherence in a larger population and the relationship with demographic characteristics.
Incidence of interstitial lung disease and cardiotoxicity with trastuzumab deruxtecan in breast cancer patients: A systematic review and single-arm meta-analysis
Authors: Soares Leonardo Ribeiro , Rosa Victor Domingos Lisita , Vilbert Maysa , Oliveira Jéssica Lopes de , Deus Mariana Moreira de , Freitas-Júnior Ruffo
Published: January 2024

Objective: We performed a systematic review and meta-analysis to assess the incidence and severity of those adverse events (AEs) in metastatic breast cancer (mBC) patients treated with trastuzumab deruxtecan (T-DXd). Methodology: We comprehensively searched PubMed, Cochrane, and Scopus databases for randomized clinical trials (RCTs) and observational cohort studies, including mBC patients with HER2-low or -positive expression who have received at least one dose of T-DXd. The DESTINY-Breast02 study was also included after its presentation at the SABCS 2022. Our meta-analysis followed the Cochrane Reviews and PRISMA statement guidelines. The statistical analysis was performed using the R software, and the results are presented as pooled analysis in forest plots. Results: We included nine studies: three phase III RCTs, three phase II and two phase I non-RCTs, and one retrospective cohort comprising 1,443 patients with a mean follow-up of 14.9 months. The median age of our population ranged from 53 to 59 years. Most were non-Asian (40.5%) and presented with hormone-receptor-positive mBC (66.8%). In a pooled analysis, the incidence of ILD was 13.0% (179 patients; 95%CI 11.0–13.0). Patients enrolled in phase III clinical trials had an ILD rate of 12.0%, while the observational cohort reported a numerically higher rate of 18.0%. Most ILD cases, 84.9% (152 patients), were mild (grade 1 or 2). Grade 3 or 4 AEs were reported in 13 (7.3%) patients, and grade 5 in 14 (7.8%) patients. We assessed cardiotoxicity by the reduction of left ventricular ejection fraction (LVEF) compared with baseline measures. Decreased LVEF was seen in 3.6% (95%CI 3.0–5.0%), and most patients were asymptomatic. A total of 11 patients developed prolonged QT interval, and four had left ventricular dysfunction and cardiac failure. Conclusion: Our meta-analysis reinforces the importance of close vigilance for pulmonary and cardiac toxicities in mBC patients on treatment with T-DXd. Early detection and management by a multidisciplinary team following the most recent guidelines may improve patient outcomes.
Adherence of community health agents (ACS) to a breast cancer screening program – ITABERAÍ project
Authors: Correa Rosangela da Silveira , Rodrigues Danielle Cristina Netto , Costa Christina Souto Cavalcante , Soares Leonardo Ribeiro , Santos Nicaella Eterna de Oliveira , Sá Maria do Carmo Egito de , Silva Douglas Euclides de , Freitas-Júnior Ruffo
Published: January 2024

Objective: The ITABERAÍ Project is a study that deals with intervention through the training of community health agents (ACS) based on evidence of tracking in physical examination of the breast. The objective of this study was to evaluate the ACS adherence to a breast cancer screening program carried out in the city of Itaberaí. Methodology: This is a clinical, controlled, randomized, multicenter, phase III trial, where the observation unit was the ACS in its Family Health Team (ESF). Randomization was performed by a conglomerate, according to the geographic location of the ESF and the respective Basic Health Unit (UBS). The UBS were randomly drawn and allocated into the control group (CG) and intervention group (IG). Information on the sociodemographic profile, life habits, and anamnesis was collected and analyzed. Results: A total of 75 ACS participated in the study, where the mean age in the CG was 46.68±8.68 years, and in the IG, it was 49±9.33 years (p=0.27), and the time working as an ACS was 17.09±7.15 years in the CG and 16.38±8.02 years in the IG (p=0.69). There was no significant difference in educational level between the groups (p=0.59). A total of 1,963 women were registered, 1,261 of which by the ACS in the CG and 742 in the IG (p=0.01). Conclusion: At the beginning of the study, there was greater adherence by the ACS in the CG compared with the ACS in the IG. This may configure the need for greater training of the ACS of the IG, both to perform the physical examination and in the aspect of how to approach the woman for her inclusion in the study.
Immunotherapy vaccines for triple-negative breast cancer and its influence on the tumor microenvironment
Authors: Camargo Luana Cristina , Longo Joao Paulo Figueiro , Paiva Karen Letycia Rodrigues de , Simões Marina Mesquita , Bergmann Thais , Silva Victor Carlos Mello da
Published: January 2024

Objective: Cancer is still a complex and debilitating disease even though advances in treatment have occurred. Triplenegative breast cancer (TNBC) is an aggressive subtype of breast cancer with a poor prognosis and occurs more frequently in young women. Due to its metastatic features and unique tumor microenvironment, TNBC treatment is limited. In this study, we evaluated how three chemotherapy drugs could be used to produce vaccines with cells under immunogenic cell death. Methodology: For that, 4T1-luc2 cells were treated with cisplatin (100 μM), mitoxantrone (MTX) (15 μM), and doxorubicin (DOX) (50 μM) for 24 h. Then, the treated cells were injected subcutaneously in tumor-bearing Balb/c female mice, after the tumor challenge. The treatment occurred three times, once a week. During and after the treatment, primary tumor and metastatic progression were followed using the chemiluminescence technique. After 5 weeks of the tumor challenge, mice were euthanized and organs (liver, tumor, lungs, and spleen) were collected for analysis. Additionally, the spleens were processed for flow cytometry for regulatory T lymphocyte and myeloid-derived suppressor cells analysis. Results: Cisplatin and MTX vaccines slowed the primary and metastatic tumor growth as well as the decreased tumor, liver, and spleen weight, while the DOX vaccine slowed the metastatic tumor progression in the lungs but did not alter tumor and other organs’ weight. Moreover, cisplatin and MTX vaccine increased the ratio of lymphocytes in the spleen but not the DOX vaccine. All comparison was done regarding the tumor-bearing mice treated with PBS. Conclusion: Taken together, both MTX and cisplatin vaccines treated primary and secondary tumors probably by the increase of lymphocyte recruitment, and the cisplatin vaccine also has an influence on the tumor microenvironment. Finally, the therapeutical vaccine might be an interesting approach as a treatment for TNBC due to its positive effect on metastasis and tumor microenvironment, especially with cisplatin.
Evaluation of upper limb lymphedema using spectroscopic bioimpedance in a Brazilian population
Authors: Vieira René Aloisio da Costa , Tozzo Fabiola Cristina Brandini da Silva , Sarri Almir José , Souza Cristiano de Pádua , Oliveira Marco Antônio
Published: January 2024

Objective: Upper limb lymphedema secondary to breast cancer treatment is a disabling, chronic, and often incurable sequel, resulting from lymphatic insufficiency. There are several methodologies for diagnosing lymphedema, such as volumetrics (considered the gold standard), perimetry (the method most used in clinical practice due to its ease of application), perometry, lymphoscintigraphy, and computed tomography, which are high-cost equipment and are not superior to other methods, and spectroscopic bioimpedance (BIS), which allows the early diagnosis of lymphedema. Early detection is related to lower costs in the treatment of this comorbidity and less impact on the quality of life of these women; however, there are still no studies using BIS to assess lymphedema in the Brazilian population. The aim of this study was to analyze the validity of BIS as a method for diagnosing lymphedema in Brazilian women undergoing treatment for breast cancer and compare it with other methods. Methodology: A cross-sectional prospective study was carried out at Hospital de Amor, evaluating 462 women undergoing treatment for breast cancer, from May 2015 to January 2021. Lymphedema was evaluated using different methodologies. BIS results were compared with direct volumetry. L-Dex® technology/BIS equipment from ImpediMed® was acquired using FAPESP grant under the number 2014 08197-0. The study was approved by the local ethics committee under the numbers 782/2014 and CAAE 28140214.1.0000.5437. Results: When comparing patients with lymphedema diagnosed by direct volumetry with those diagnosed by BIS, BIS did not diagnose lymphedema in 52 of the 93 patients with lymphedema. BIS sensitivity was 44.1%, specificity 95.4%, PPV was 70.7%, NPV was 87% and Kappa was 0.459. When performing the ROC curve between BIS and volumetry, a good area under the curve was obtained (AUC=0.75) and a possible cutoff point of L-Dex® ³7.35 with a sensitivity of 57%, a specificity of 90.9%, and kappa value=0.489. Conclusion: BIS showed low sensitivity and concordance and did not prove to be a valid method for diagnosing lymphedema in Brazilian women.