bluuebunny/crossref_metadata_2025 huggingface dataset:
Seismic structure of South-Central Andes of Colombia by tomographic inversion
Authors: Vargas Carlos A. , Pujades Luís G. , Montes Luis
Published: May 2021

Ha sido estimada la estructura de velocidad Vp en 3D bajo el Noroccidente de la Región Andina Suramericana mediante la aplicación de un método tomográfi co a 5671 primeros arrivos de la onda P asociados a 499 eventos locales que fueron registrados por 16 estaciones sísmicas permanentes de la Red Sismológica Nacional de Colombia y que comprenden el período Diciembre de 1992 hasta Junio de 1999. Para el efecto fueron postuladas siete capas de velocidad de onda P uniformes con profundidades 5.0 km, 15.0 km, 25.0 km, 40.0 km, 60.0 km, 80.0 km y 100.0 km y que asocian la sismicidad producida por los límites de las placas Nazca, Suramericana y Caribe. La estructura Vp sugiere la existencia de zonas de baja velocidad que subyacen en las regiones volcánicas. Un área de alta velocidad en el sector 77°W - 4°N interrumpe las zonas de baja velocidad (rocas parcialmente fundidas) y parece responder a la presencia de una estructura anticlinal relacionada con el manto superior. Esta región de contrastes de velocidad marca el límite entre una subducción más inclinada hacia el norte con respecto al sector sur como respuesta al acople de la placa Caribe y del Bloque Chocó en el sector norte sobrelapandose sobre la placa Nazca.
Gravity anomalies, sub-surface structure and oil and gas migration in the Mamfe, Cameroon-Nigeria, sedimentary basin
Authors: Ndougsa-Mbarga Théophile , Manguelle-Dicoum Eliezer , Campos-Enriquez José-Oscar
Published: May 2021

Este estudio reporta resultados preliminares de una interpretación formal de datos existentes de un área hasta hoy desprovista de estudios geofísicos, la cuenca de Mamfe (Camerún nor-occidental/ Nigeria sur-oriental). La importancia de esta cuenca se comprende por el hecho de que está genéticamente relacionada con la depresión de Benue productora de hidrocarburos. Los mapas de anomalías gravimétricas regional y residual proporcionaron información sobre la estructura de la cuenca. Las componentes gravimétricas regional y residual se obtuvieron ajustando con el método de mínimos cuadrados una superfi cie polinomial de tercer grado a la anomalía de Bouguer. La anomalía residual de tercer orden revela la presencia de dos bajos gravimétricos orientados NE-SW. La anomalía occidental cubre las poblaciones de Ekok y Agbokem, y la oriental comprende a Mukonyong, Mamfe y Bachuo Akagbe. Dos cinturones orientados aproximadamente E-W de anomalías gravimétricas positivas limitan por el norte y el sur respectivamente a las anomalías antes descritas. En general los bajos gravimétricos son debidos al relleno sedimentario de la cuenca, en tanto que las anomalías residuales positivas son el producto de afloramientos del complejo basamental. El patrón de las anomalías nos permite inferir las características generales de la cuenca. Ella comprende dos sub-cuencas separadas por un alto estructural. La cuenca occidental es la más profunda y compuesta. Comprende dos sub-cuencas separadas por un alto estructural menor, posiblemente relacionado con la continuación hacia la cuenca del complejo cristalino. En general, estas sub-cuencas tienden a ser más someras hacia el oriente indicando que la cuenca evolucionó de oeste a este. Las direcciones de migración de hidrocarburos probablemente generados en el depocentro han sido indicadas. La acumulación de hidrocarburos a lo largo de estas direcciones es posible, pero estudios sísmicos y gravimétricos más detallados deben ser emprendidos para buscar trampas estructurales o estratigráficas. Este estudio puede servir de base a un programa integral de exploración petrolera.
Tidal Current Components in the Southern Bay of Campeche, Gulf of Mexico
Authors: Salas-de-León David A. , Monreal-Gómez María A. , Salas-Monreal David , Expósito-Díaz Gilberto , Riverón-Enzastiga Mayra L. , Vázquez-Gutiérrez Felipe
Published: May 2021

Datos sobre la magnitud y dirección de las corrientes fueron obtenidos en la Bahía de Campeche, al sur del Golfo de México, de marzo a mayo de 1997, para obtener las principales componentes de marea en la región. Las elipses y fases de las diferentes componentes de marea fueron obtenidas mediante un ajuste por mínimos cuadrados acoplado con una modulación nodal a partir de las series horarias de corrientes por marea. Los constituyentes P1 y K2 se infi rieron a partir de los constituyentes K1 y S2, respectivamente. Los resultados muestran la dominancia del armónico K1 en la plataforma continental al sur de la Bahía de Campeche, una región de mareas mixtas con dominancia semidiurna en la zona del umbral de Cayo Arcas y una región de transición entre Cayo Arcas y las estaciones al oeste en la zona de estudio. Las diferencias en las amplitudes de las corrientes de marea en la vertical fueron despreciables, mientras que las diferencias en las fases muestran un retraso significativo entre la superficie y el fondo. El sentido de rotación de las elipses de marea en Cayo Arcas es negativo, mientras que en las otras estaciones fue positivo. Cayo Arcas tiene una fuerte influencia en las corrientes de marea ya que su fase y sentido de rotación varían.
Insights into the Invitro Antioxidant, Anti-Inflammatory and Anticancer Activities of Limonia acidissima Fruits
Authors: S. Sujitha  , P. Venkatalakshmi
Published: May 2021

Wood apple botanically identified as Limonia acidissima is an indigenous fruit with amazing nutritional and health benefits. Reports from traditional literature of Ayurveda and Siddha portrays the medicinal properties of this fruit. The scooped pulp of the ripe fruit is consumed as such or it can be made into different recipes. But inclusion of this fruit in our diet is not found as a regular practice. Many people are still unaware of the benefits of this fruit. Hence, this study was taken up to unravel the biological potencies of this fruit by conducting in vitro experiments. Phytochemicals such as alkaloids, flavonoids, phenols, saponins and ascorbic acid have been estimated. Anti-inflammatory activity of the aqueous extract of fruit pulp combined with outer rind has been evaluated through inhibition of albumin denaturation. Among the 5 different concentrations (200, 400, 600, 800, 1000 µg/ml), at 1000 µg/ml wood apple has shown 74.55% of protein denaturation inhibition which was compared with standard Diclofenac sodium. Antioxidant capacity of the extract was expressed as mg/100g ascorbic acid equivalent through phosphomolybdenum assay. Dose dependent increase in the antioxidant activity was observed. About 8 different concentrations of the aqueous extract of L. acidissima were evaluated for their cytotoxic activity on MCF 7 cell line. At a concentration of 1000 µg/ml, the extract has shown 93.43% of cytotoxicity and 6.57% of cell viability. Apoptotic induction was evaluated and confirmed by the formation of DNA ladders through DNA fragmentation assay. GCMS analysis of wood apple fruit pulp and rind revealed the presence of several phytochemicals among which   many of   them had therapeutic activity reported earlier.
Impact of Azithromycin and 8-Hydroxychloroquine in 2019 Novel Coronavirus (COVID-19) Pandemic: A Systematic Review
Authors: Srikanta Chandra  , Preeta Bose  , Jyoti Saxena  , Muniraj Bhattacharya  , Arun dutta  , Jyotirmay Samanta  , Lucky Mukherjee
Published: May 2021

As we know  novel  coronavirus  is an emergent  nuisance  in this stipulated  period.  Corona  virus  is a group  of enveloped  viruses,  with  non-segmented,  single  stranded &  positive  sense  RNA genomes.  Human  Corona virus  is mainly subdivided into four categories such as 229E, NL63, OC43, HKU1. Epidemiologically it has a greater prevalence in the modern era. The features encountered in the clinical course of the disease are multifarious spanning from cough, sneezing, fever, breathlessness.   It   may   take   2-14   days   for   a   person   to   notice   symptoms   after   infection.      Azithromycin   and   8 Hydroxychloroquine  both    plays an instrumental role for management of COVID-19. Azithromycin is a  macrolide antibiotic and it  binds with a 50s ribosome   then inhibits   bacterial   protein synthesis. On the other hand 8-Hydroxychloroquine  was approved by United State in the year of 1955 .Basically it is used as a antimalarial drugs . Briefly, in inflammatory conditions it binds with toll like receptor & blocks them.  8- hydroxychloroquine    increases  lysosomal pH in antigen presenting cells  . In inflammatory conditions it blocks toll like receptors on plasmacytoid dendritic cells. In our review we focused on  the role of Azithromycin, and 8-hydroxychloroquine in Covid-19 .
Torah against the Virus, Rabbis against the Government: Ultra-Orthodoxy Facing the Pandemic
Authors:   Russian State University for the Humanities, Zelenina Galina
Published: May 2021

The paper discusses a number of the most remarkable responses to the COVID‑19 pandemic and to the social isolation measures coming from several, mostly ultra‑Orthodox, Jewish communities in Israel, the United States, and Russia. It examines major elements of the crisis discourse, i.e., the hermeneutics of the causes and meanings of the pandemic; the affirmation of group borders and hierarchies as a result of the search for culprits; the relations between the religious community and the state; as well as the possible transformations of social behavior and ritual practices resulting from the crisis.
Europe and the Muslims: Debating the Foundations of State Policy
Authors:   Ye.T. Gaidar Institute for Economic Policy (Moscow, Russia), Starodubrovskaya Irina
Published: May 2021

This article discusses theoretical issues behind the current shift in the policy of European states towards Islamic communities. The shift is driven by the idea that the values of political Islam are incompatible with Western values; that the main driver behind radicalization is ideology and that even non‑violent Islamists gradually prepare the Muslim youth to embracing violence. Based on current academic discussions as well as the results of the author’s own research, the author concludes that the opponents of these ideas have serious counter‑ arguments. In their views, radicalization can be explained by a wide range of different factors. Violent and non‑violent Islamists compete for the audience, and therefore, not only can non‑violent Islamists embrace jihadist views but also, vice versa, some jihadists can change their position to non‑violence. Moreover, Muslim values, as well as those of the Islamists, are not necessarily antagonistic in all their aspects with the values of Western democracies. Various theoretical approaches form the basis for an alternative program of practical measures that could be implemented in the future.
Pemanfaatan Trichokompos Pada Budidaya Sayuran Organik Sebagai Kegiatan Entrepreneurship Himae
Authors: Jasminarni Jasminarni , Lestari Ardiyaningsih Puji , Evita Evita , Novita Trias
Published: May 2021

Kegiatan ini bertujuan meningkatkan pengetahuan dan ketrampilan mitra  melalui pendampingan, penyuluhan dan demontrasi tentang pemanfaatan  trichokompos pada budidaya sayuran organik sebagai kegiatan Entrepreneurship HIMAE (Himpunan Mahasiswa Agroekoteknologi). Secara umum target luaran yang akan dicapai akan memberi dampak terhadap Masyarakat umumnya dan kelompok mitra khususnya, serta masyarakat disekitarnya. Dampak positif yang diharapkan tercapai melalui kegiatan ini dimana tim pengabdiaan akan melakukan pelatihan dan demontrasi  kelompok HIMAE sebagai mitra dalam hal pemanfaatan trichokompos yang merupakan hasil produk pada kegiatan PPM tahun sebelumnya sebagai pupuk dan juga dapat berdampak terhadap lingkungan yang bersih dan sehat. Tim pengabdian juga  akan memberikan cara cara  untuk meningkatkan nilai jual produk sayuran organik dengan cara  membuat kemasan.  Diharapkan dari upaya tersebut produk sayuran organik   yang dihasilkan dapat dijadikan sebagai kegiatan wirausaha yang bernilai ekonomi bagi HIMAE, sehingga dapat menjadi tambahan penghasilan bagi mitra. Luaran yang dihasikan  adalah berupa produk sayuran organik. Pemanfaatan trichokompos pada budidaya sayuran merupakan salah satu upaya membantu mengatasi pencemaran lingkungan dan kerusakan lahan akibat penggunaan pupuk kimia. Hasil yang didapat dari kegiatan ini adalah meningkatnya pengetahuan mitra tentang pentingnya  penggunaan pupuk organik pada budidaya sayuran organik yang dihasilkan. Sayuran organik yang dapat di kosumsi dan di jual sebagai kegiatan Entrepreneurship HIMAE
O desenvolvimento da marca de um país: é possível estimular o reconhecimento internacional de um Brasil tecnológico e inovador?
Authors: Machado Luis Fernando Corrêa da Silva
Published: May 2021

Este artigo analisa as razões de esforços empreendidos para promover a narrativa de um Brasil tecnológico e inovador no exterior. A premissa é de que países investem em iniciativas de diplomacia pública e marketing a fim de melhorar a inserção internacional de produtos, serviços ou processos tecnológicos, bem como a atração de investimentos e mão de obra qualificada estrangeiros. O propósito da pesquisa é o de identificar limitações e fortalezas da diplomacia pública brasileira para se alcançar o desenvolvimento da marca-país no setor de tecnologia. Trata-se de pesquisa exploratória, que recorre à análise de bibliografia especializada e de estratégias adotadas por cinco países (Estônia, Índia, Suécia, Suíça e Reino Unido), para fins ilustrativos, com vistas à compreensão do problema. Concluiu-se que para que se atinja esse objetivo a atuação da Chancelaria não é suficiente. Todos os órgãos do governo, em níveis federal, estadual e municipal e, de preferência, também do empresariado e da sociedade civil deveriam estar envolvidos. Este trabalho sugere que o SICOM concentre o processo decisório da formulação e implementação da política da marca-Brasil, inclusive do componente tecnológico.
Juventude e os desafios do processo de integração ao ambiente universitário: aproximações com a realidade da Faculdade de Educação da Universidade Federal do Amazonas
Authors: Falcão Nádia Maciel , Abtibol Margareth Soares , Santos Miriane Feitoza dos
Published: April 2021

Analisa as ações de integração de novos estudantes ao ambiente universitário, desenvolvidas na Faculdade de Educação da Universidade Federal do Amazonas, ancorando-se no debate atual sobre o processo de transição do ensino médio à educação superior no Brasil. A metodologia, de abordagem qualitativa, sustenta-se em referenciais teórico-metodológicos da pesquisa em educação, dialogando com estudos de juventude. Os dados resultam de revisão bibliográfica e análise de documentos. Os resultados apontam queo processo de integração de novos estudantes nos cursos de graduação instigarum debate multidimensional que considere aspectos estruturais que permeiam o contexto de expansão do acesso à educação superior; aspectos institucionais que se expressam em diferentes graus de produção de suporte aos jovens recém ingressos na educação superior; além da indispensável discussão no campo das subjetividades. Na experiência institucional explorada no estudo, observa-se um esforço de integração articulado sobre princípios de deliberação coletiva, participação de diferentes atores e continuidade. Experiência que pode ser favorecida pela inserção de processos de escuta dos jovens.
Bruton’s tyrosine kinase (BTK) regulates myeloid cell recruitment during acute inflammation
Authors: Purvis Gareth , Aranda Haidee , Channon Keith , Greaves David
Published: May 2021

Bruton’s tyrosine kinase (BTK) is a non-receptor kinase best known for
its role in B lymphocyte development that is critical for proliferation,
and survival of leukaemia cells in B cell malignancies. However, BTK is
expressed in myeloid cells, particularly monocytes and macrophages where
its inhibition has been reported to exhibit anti-inflammatory
properties. Therefore, we explored the role of BTK on the migration of
myeloid cells in vitro and in vivo. Using the zymosan induced
peritonitis model of sterile inflammation we demonstrated that acute (1
h prior to zymosan) inhibition of BTK using a wide range of FDA
(Ibrutinib and Acalabrutinib) and non-FDA approved inhibitors (ONO-4059,
CNX-774, Olumatinib and LFM-A13) reduced neutrophil and monocyte
recruitment. XID mice, which have a point mutation in the Btk gene had
reduced neutrophil and monocyte recruitment to the peritoneum following
zymosan challenge. To better understand the role of BTK in myeloid cell
recruitment we investigated both chemotaxis and chemokine production in
monocytes and macrophages. Pharmacological or genetic inhibition of BTK
signalling substantially reduced human monocyte and murine macrophage
chemotaxis to a range of chemoattractants (complement C5a and CCL2). We
also demonstrated that inhibition of BTK in tissue resident macrophages
significantly decreases chemokine secretion by reducing NF-kB activity
and Akt signalling. Our work has identified a new role of BTK in
regulating myeloid cell recruitment via two mechanisms, 1) reducing
monocyte/macrophages’ ability to undergo chemotaxis, and 2) reducing
chemokine secretion, via reduced NF-kB activity in tissue resident
macrophages.
A Key to T1D Prevention: Screening and Monitoring Relatives as Part of Clinical Care
Authors: Greenbaum Carla J.
Published: April 2021

The 2019 report of a randomized, placebo-controlled clinical trial demonstrating that immune therapy can delay the onset of clinical type 1 diabetes (T1D) in antibody-positive relatives by a median of 2 years stands out as a landmark in the decades-long effort to prevent T1D. With this important step achieved, it is now time to consider what is needed to bring disease-modifying therapy for prevention or delay of T1D to clinical use from this point. Long considered a chicken and egg problem (why screen for T1D risk when we have no therapy, and how can we develop therapies without more screening), we now have the opportunity to break this impasse. The purpose of this article is to place this clinical trial result in context, highlighting key foundational studies leading to this accomplishment, addressing the current gaps, and suggesting that a key next step for prevention of T1D is to screen and monitor relatives for T1D risk in the context of clinical care.
Evaluasi Pengendalian Inflasi di Kota Bandar Lampung Tahun 2018
Authors:   Universitas Lampung, Sari Vivi Monica , Utoyo Bambang ,   Universitas Lampung, Tresiana Novita ,   Universitas Lampung
Published: May 2021

Inflation is one of the economic problems of a country including Indonesia. One of the efforts of the Indonesian government to control inflation is by coordinating with Bank Indonesia to establish an Inflation Control Team at the central and regional levels, through which the program is implemented to control inflation. The purpose of this research is to evaluate inflation control conducted by the Bandar Lampung City Government through the Bandar Lampung Regional Inflation Control Team in the foodstuffs group which is one of the contributing factors to high inflation in 2018. This research uses descriptive research method with qualitative approach, and uses data collection technique by interview, observation and documentation. Data analysis techniques used in this research are data reduction, data presentation, and conclusion drawing, while for data validity techniques using observation and triangulation extension techniques. This research uses Karl Ludwig Bartelenfy's evaluation model of input, process, output, results, and impact evaluation. The results of this study concluded that in controlling the inflation of foodstuff groups the Regional Inflation Control Team through the food task force carried out various programs of activities, among others, monitoring, coaching, market inspection and monitoring market prices, as well as market operation or cheap markets. From the activities program can be seen how the development of market prices, minimizing the circulation og products that do not meet the standards, and the availability of foodstuff. Program of activities have iven quite good results, this can be seen from the trendline chart taht shows a decrease in the foodstuff. Although it has not been significantly due to constraints on the budget, it also has a good impact in addition to the decrease in the inflation index but also on increasing cooperation with new partners that is expected to help and facilitate efforts to control inflation in the future.
Is Historical Study of Nahwu on Madrasah Basra and Kufa Important to Teach? The Analysis of Opinion on Indonesian AFL Students
Authors: Febriyanti Ulfa , Abdurrahman Maman , Sopian Asep
Published: May 2021

The knowledge of nahwu has been taught in many universities in Indonesia. However, the study of the nahwu taught is still limited to a study oriented to the science of tools in learning Arabic and ignores historical, theoretical aspects such as Madrasah Basra and Kufa. Therefore, this study aims to prove whether this historical, academic study is essential to be taught to Indonesian AFL students. This research uses a quantitative approach with a descriptive type. The questionnaire was given to several 20 fifth-semester AFL students with three open-ended questions about their knowledge of Madrasah Basra and Kufa. The results of this study indicate that 60% of students are familiar with Madrasah Basrah and Kufa. Most of them hear about Madrasah Basrah and Kufa for the first time in college (75%), in pesantren (8.3%), on the internet (8.3%), at high school (8.3%), and from the sermon (8.3%.). Moreover, the students generally know about Madrasah Basrah and Kufa's differences, but it is only limited to the differences in terms and I'rab. Therefore, the learning of nahwu needs to be developed by paying attention to the historical aspects of the nahwu development, especially the differences from Madrasah Basrah and Kufa.
Kandungan Protein Kecap Nira Lontar dengan Variasi Konsentrasi Tepung Tempe
Authors: Ledo Mellissa Erlyn Stephanie
Published: May 2021

Soy sauce is generally made from soybeans. However, palm oil has the potential to be used as an ingredient in soy sauce which can be combined with tempeh flour. This study aims to assess the protein content of lontar juice with variations in the concentration of tempeh flour. The research method used in this study was an experimental method with a completely randomized design (CRD) factorial, with the treatment of tempeh flour concentrations of 0%, 3%, 5%, 7%, 10%. The results showed that the treatment with the addition of 10% tempeh flour gave the product with the highest protein content compared to other treatments, namely 4.90%. In addition, the organoleptic test of soy sauce which includes color, aroma, taste, and viscosity in the addition of 10% tempeh flour showed the best results.
Exploração Sexual no Brasil: Um Balanço dos Trabalhos da CPI do Congresso Nacional
Authors: Gomes Patrícia Sabóia
Published: April 2021

O artigo se propõe a apresentar um relato da atuação da Comissão Parlamentar Mista de Inquérito para investigar a situação da exploração sexual no Brasil, apontando-se, ao final, as recomendações que foram apresentadas para alteração na legislação vigente.
O CONTEÚDO NORMATIVO DOS PRINCÍPIOS ORIENTADORES DA MEDIAÇÃO
Authors: Meira Danilo Christiano Antunes , Rodrigues Horácio Wanderlei
Published: April 2021

Este artigo tem o objetivo de indicar as possíveis normas que podem ser extraídas dos princípios orientadores da mediação. A análise é feita por uma abordagem semântica e sistemática dos enunciados. Além disso, busca identificar quais princípios são aplicáveis às modalidades judicial e extrajudicial da mediação. Os princípios analisados são aqueles instituídos pelos marcos normativos da mediação: autonomia da vontade, boa-fé, busca do consenso, competência, confidencialidade, decisão informada, empoderamento, imparcialidade, independência, informalidade, isonomia entre as partes, oralidade, respeito à ordem pública e às leis vigentes e validação. Como conclusão, indica as principais dificuldades que devem ser enfrentadas pelos atores envolvidos no procedimento da mediação.
DIREITO DE LAJE: DA IMPORTÂNCIA SOCIAL E DAS CONTROVÉRSIAS QUANTO AO DIREITO DE SUPERFÍCIE E AO CONDOMÍNIO EDILÍCIO
Authors: Cabral Rafael Lamera Giesta , Gama Vanessa Dias de Carvalho  Quaresma
Published: April 2021

O presente estudo tem como objeto avaliar as concepções do direito de laje como uma política de desenvolvimento e regularização urbana e ao final indicar uma classificação que melhor represente a natureza jurídica desse instituto. A análise do direito de laje foi concretizada a partir dos parâmetros de aplicação dos princípios da dignidade humana, da função social da propriedade e do direito à moradia, a fim de demonstrar seu caráter fundamental de ruptura às clássicas concepções do direito de propriedade. Para que o objetivo fosse alcançado, buscou-se apresentar o percurso legislativo do direito de laje e sua origem na doutrina nacional e internacional. Na sequência foi realizada uma análise detalhada acerca das concepções do direito de laje, especialmente, no tocante ao direito superficiário e ao condomínio edilício, que também guardam similitudes com o instituto. O direito de laje pode ser considerado sui generis, com traços distintos das funções sociais exercidas pelo direito de superfície e condomínio edilício, com forte vocação para a regularização de uma política urbana em aglomerados populacionais.
FAKE NEWS À LUZ DA RESPONSABILIDADE CIVIL DIGITAL: O SURGIMENTO DE UM NOVO DANO SOCIAL
Authors: Pereira Guimarães Glayder Daywerth , César Silva Michael
Published: April 2021

A pesquisa tem por objetivo analisar a responsabilidade civil digital, sob o prisma do direito dos danos, com enfoque relacionado a divulgação de Fake News, verificando-se a existência, ou não, de danos diversos advindos da conduta de disseminar notícias falsas. Neste estudo, buscou-se evidenciar as implicações das Fake News, principalmente, no que se refere a pós verdade, abordando a temática da liberdade de expressão, bem como as hipóteses de abuso do direito, no ordenamento jurídico brasileiro, culminando na temática dos novos danos. A pesquisa proposta pertence à vertente metodológica jurídico-sociológica. No tocante ao tipo de investigação foi escolhido, na classificação Witker (1985) e Gustin (2010), o tipo jurídico-projetivo. De acordo com a técnica de análise do conteúdo, afirma-se que se trata de uma pesquisa teórica, o que se mostrou possível a partir da análise de conteúdo da doutrina, jurisprudência e legislação pertinente. Por fim, restou determinado que as Fake News se inserem como elemento ocasionador de danos, não somente morais ou materiais, sendo vislumbrável a hipótese de danos sociais em função do resultado da conduta de disseminação de notícias falsas na sociedade contemporânea.
Vliyanie novoj koronavirusnoj infekcii COVID-19 na sistemu «mat'–placenta–plod»
Authors: Низяева Н. В. , Ломова Н. А. , Долгополова Е. Л. , Петрова У. Л. , Карапетян Т. Э. , Шмаков Р. Г. , Франкевич В. Е.
Published: May 2021

Narushenie razvitiya placenty na rannih srokah beremennosti, associirovannoe s sistemnym porazheniem endoteliya sosudov pri COVID-19, mozhet privesti k ryadu oslozhnenij. Cel'yu issledovaniya bylo vyyavit' gistologicheskie i immunogistohimicheskie (IGH) osobennosti tkani placenty u beremennyh zhenshchin s COVID-19 na raznyh srokah gestacii i izuchit' ih rol' v patogeneticheskih mekhanizmah bolezni v sisteme «mat'–placenta–plod». Issledovali dve gruppy beremennyh: osnovnuyu iz 66 pacientok s COVID-19 i gruppu sravneniya iz 40 zhenshchin bez priznakov virusnoj infekcii. Vypolnyali makroskopicheskoe, mikroskopicheskoe i IGH-issledovaniya obrazcov placent. Proveden analiz kliniko-anamnesticheskih harakteristik pacientok s COVID-19 s uchetom tyazhesti techeniya zabolevaniya, rodorazresheniya i perinatal'nyh iskhodov. Pri IGH-okrashivanii pervichnymi antitelami u pacientok s tyazhelym i srednetyazhelym techeniem SOVID-19 povyshena ekspressiya v strukturah placenty provospalitel'nyh faktorov (TNFα, IL8) i snizhen uroven' protivovospalitel'nyh (IL4) (r < 0,05). V obrazcah placent zhenshchin osnovnoj gruppy detektirovana perestrojka vorsinchatogo dereva s razvitiem subklinicheskoj placentarnoj nedostatochnosti, v ryade sluchaev dekompensiruemoj v rodah, s razvitiem klinicheskoj kartiny ostroj gipoksii ploda. U materej s COVID-19 sleduet vybirat' akusherskuyu taktiku individual'no s uchetom faktorov riska i provedeniem v rodah nepreryvnoj kardiotokografii. Celesoobrazno provodit' IGH-issledovanie placenty rodil'nic s COVID-19 dlya utochneniya taktiki vedeniya novorozhdennogo i prognoza vozmozhnyh neonatal'nyh oslozhnenij.
Transformation of university teachers’ professional activity during the pandemic
Authors: Ilina Irina Y. , Arkhipova Nadezhda I. , Nazaikinskii Svyatoslav V. , Sedova Оlga L. , Jukova Evgeniya E.
Published: May 2021

The transition of the educational system to a distance format due to the spread of COVID-19 has led to a transformation in the nature and content of professional activities of university teachers. A wide range of research methods, the results of sociological surveys and interviews, as well as an analysis of text arrays from Internet resources, are used to assess the socio-psychological consequences of remote employment. Drawing a conclusion on their remote employment, teachers note the acquisition of a unique experience consisting not only in the mastery of online educational technologies but also in the implementation of new models of professional interaction with students and colleagues. Teachers associate the perspectives for further transformation of their professional activity with the formation of new combined (multi-format) models of education. At the same time, there forms a system of negative expectations as teachers believe that the launched process of transformation of education will lead to stricter requirements for the teacher as the subjects of educational and labor relations, as well as to the destabilization of the situation in the professional labor market.
THAHARAH LAHIR DAN BATIN DALAM AL-QURAN (Penafsiran terhadap Qs. Al-Muddatsir/74:4 dan Qs. Al-Maidah/5:6)
Authors: Mujahid Ahmad , Haeriyyah Haeriyyah
Published: May 2021

One of the fundamental problems of the religious diversity of most Muslims today is that they are religiously textual or infantile, minus the meaning of irfani. They are religious limited to rituals and lack of inner meaning. As a result they stop in religion at the means and do not arrive at the religious goals. For example, they only feel that they are sufficient in sharia ablution or prayer but minus the inner meaning or essence. As a result, the ablution and prayer that they perform does not lead to the essence of religion, the essence of ablution and the essence of prayer. This paper discusses how the inner or irfani meanings of the essence of thaharah and the nature of wudoo, without ignoring the core meanings (syar'iyah and bayani).
Factors affecting repositioning policy compliance: an integrative review
Authors: Iblasi Abdulkareem , Aungsuroch Yupin , Gunwan Joko
Published: April 2021

Objective

To explore the factors affecting nurses’ compliance with repositioning policy.

Methods

An integrative review was conducted following the Whittemore and Knafl methodology to identify the problem related to repositioning policy compliance. We searched the following databases: Coherence Wounds Group Specialized Register (Jan 1997 to Jun 2019), Ovid MEDLINE (Jan 1997 to Jun 2019), EBSCO CINAHL (Jan 1997 to Jun 2019), and Clinical Key database (Jan 2014 to Oct 2018).

Results

The review revealed three factors that influence repositioning compliance: nurse-related factors, patient-related factors, and Environment-related factors.

Conclusions

These factors directly impact one another and, in turn, influence the compliance of nurses to the repositioning policy. However, there is no evidence currently available that explains the collective impact of these factors and how they interact to affect repositioning policy compliance. Nevertheless, all these factors are important and should be considered to enhance and further improve the quality of nursing care and adherence to the repositioning policy.
Digital literacy practices in tertiary education: A case of EFL postgraduate students
Authors: Rinekso Aji Budi , Rodliyah Rojab Siti , Pertiwi Intan
Published: May 2021

Over the past few decades, technologies grew rapidly, transforming traditional instructions to be more digitalized and stimulating many researchers to study digital literacy practices in a school-educational context. However, studies exploring digital literacy practices in the context of tertiary education are still scarce. Within the qualitative approach, this study investigated digital literacy practices by EFL (English as a Foreign Language) postgraduate students. Moreover, it intensively discusses the kinds of digital tools used by the participants and the purposes of using them. Additionally, the way the participants conceptualized digital literacy was also elaborated. Thirty-four EFL Master students of a public university in Bandung, Indonesia, participated in this study. An online open-ended questionnaire and semi-structured interviews were applied in data collection. Meanwhile, eight dimensions of digital literacy in the Hague and Payton’s frameworks were used as the basis of the thematical analysis of the interview data. Results showed that the participants conceptualized digital literacy as soft skills for managing digital information covering the acts of searching, comprehending, evaluating, creating, and sharing. The prominent result of this study relates to how the participants used digital tools for academic/research and general purposes. Subsequently, this study recommends that tertiary education institutions provide more training on maximizing digital tools for academic writing and broader access to prepaid journal articles. Further exploration of lecturers’ digital literacy practices is highly recommended.
Teachers' beliefs and classroom practices on the use of video in English language teaching
Authors: Waluyo Budi , Apridayani Aisah
Published: May 2021

In the last decade, there has been a growing interest in exploring why teachers decide to and not to use a technological tool in their teaching practices. Teachers’ beliefs have appeared to be one of the influential factors, yet still little is known about what causes both consistencies and inconsistencies between teachers’ beliefs and their classroom practices, especially on the use of technology. Thus, to address such a gap, this study examined teachers’ beliefs about video and their use of video in English Language Teaching (ELT) along with the key factors causing the inconsistencies between teachers’ pedagogical beliefs about video and their classroom practices. A qualitative research design with semi-structured interviews involving English teachers at a private educational institution in Indonesia was employed. The collected data were analyzed by using individual topic codes and emerging themes. The findings revealed that teachers’ beliefs about the use of video in ELT were positive but inconsistent with their use of video in practices. Four key factors underlying the inconsistencies between teachers’ pedagogical beliefs about video and their use of video in classroom teaching were identified, which involved teaching philosophy, teacher’s knowledge and skill, facility, and reading literature. Therefore, pedagogically, the findings implicate that teachers’ beliefs and classroom practices can be bridged by addressing the four underlying factors.
Inversion and word order in English: A functional perspective
Authors: Assaiqeli Aladdin , Maniam Mahendran , Farrah Mohammed
Published: May 2021

English is an SVO (Subject, Verb, Object) word order language. This canonical SVO pattern is the default unmarked word-order configuration typical of English, which makes this language to be classified under the typology of SVO languages. However, driven by the major purpose of language as an instrument of human communication and social interaction, and as a semantic system for making meanings, addressors sometimes depart in their discourse from this basic canonical order of constituents where a grammaticalized system like inversion takes place, resulting in inverted constructions. Through testing and developing the Degree of Focus Hypothesis, proposed by Huffman (1993), this study, which employed a mixed methods research design, sought to explore the communicative and semantic values of inversion; and the pragmalinguistc functions of preposing, i.e., clause-initial adjuncts, to the pragmatic process of communication. The study confirmed the Degree of Focus Hypothesis where the hypothesized notion of concentration of attention stemming from inversion was found to be applicable. The paper stressed that what triggers inversion or non-inversion is a certain communicative effect such as focus rather than a relation of formal determination where one element determines mechanically the form or appearance of another. A contribution to linguistic and educational research, the paper, therefore, highlighted the importance of a human factor in the functioning of language and emphasized the need to break away from grammar-based teaching (traditional grammar) to discourse-based language teaching (communicative grammar) where languaging rather than language should be the focus of language teaching and learning.
Tanggap Pertumbuhan dan Perkembangan Jagung Ketan terhadap Pemberian Amelioran dan Pupuk NPK pada Tanah Ultisol
Authors: Harini Dini , Radian  , Iwan Sasli
Published: April 2021

Pengaplikasian jenis bahan organik sebagai amelioran dan pemupukan NPK dapat menambah kesuburan tanah ultisol melalui sifat fisik dan kimia. Tujuan penelitian untuk mempelajari pengaruh jenis amelioran, dosis pupuk NPK serta interaksinya terhadap pertumbuhan dan perkembangan jagung ketan pada tanah ultisol. Pelaksanaan percobaan di Kabupaten Bengkayang, Kalimantan Barat, pada bulan Maret sampai Agustus 2020. Percobaan disusun menggunakan rancangan acak kelompok faktorial. Faktor pertama pemberian jenis amelioran dengan 5 taraf yaitu biocar bonggol jagung, bokasi berangkas jagung, bokasi jerami padi, pupuk kandang sapi, pupuk kandang ayam. Faktor kedua pemberian dosis pupuk NPK dengan 4 taraf yaitu 100, 200, 300, dan 400 kg ha-1. Jenis amelioran pupuk kandang ayam dapat menambah tinggi tanaman 2, 4, dan 6 MST, diameter tongkol, panjang tongkol, bobot per tongkol, dan bobot tongkol per petak. Dosis pupuk NPK yang tebaik untuk produksi jagung ketan yaitu 200 kg ha-1 pada panjang tongkol dan bobot per tongkol, dan dosis 100 kg ha-1 dapat memacu pertumbuhan tanaman yaitu pada tinggi tanaman 4 MST. Kombinasi jenis amelioran dari pupuk kandang ayam dan pupuk NPK 400 kg ha-1 menghasilkan bobot kering akar, bobot kering tajuk,dan laju pertumbuhan relatif yang tertinggi.

Kata kunci: bahan organik, kesuburan tanah, produksi tanaman, pupuk anorganik
Innovation cognizance and acceptance: The case of electric vehicles adoption in Ontario, Canada
Authors: Singh Ranjita , Walsh Philip , Goodfield Joshua
Published: May 2021

This study examines the results of a survey of 1,000 Canadian internal combustion engine (ICE) vehicle owners to assess factors that would encourage them to purchase an electric vehicle (EV). Further to the work of Peters and Dutschke (2014) and (Matthews et al. (2017) we combine the various drivers of EV adoption, independently identified in the literature, into one model in order to investigate their influence on the intent to purchase an EV. Through correlations and a series of probit regression modelling, we provide evidence to support additional policies that could establish greater relative advantages for owning an EV. These include the promotion of the communication of those advantages through experiential awareness initiatives such as improved access to EV test drives and consumer information. We suggest that car dealerships are important partners in this journey and their association is critical for greater diffusion of EVs in the market. Our findings have implications for EV manufacturers and government policy makers.
Sarcoma retroperitoneal: relato de caso
Authors: De Oliveira Diego Henrique , Lima Flávia Medeiros , Ramos Arthur Ribeiro , De Oliveira Gabriel Oliveira Leite , Batista Carlos Augusto Marques
Published: May 2021

Introdução: O sarcoma retroperitoneal é um tumor maligno, raro, com origem na célula mesenquimal que sofre alteração em seu código genético, produzindo assim um tecido atípico. Normalmente é uma patologia assintomática até atingir um tamanho considerável de massa, na qual, seu crescimento é o principal fator causador de sintomas. A confirmação diagnóstica se dá através de exames de imagem somadas à biopsia e estudos anatomopatológicos. O tratamento de escolha é a cirurgia, aumentando a sobrevida do paciente acometido. Objetivo: divulgar um caso de sarcoma retroperitoneal em um paciente do Hospital Escola de Valença, com seu consequente desfecho, através da análise de prontuário e estudos em literatura. Relato de caso: Homem de 65 anos atendido no Hospital Escola de Valença apresentando dor lombar e hematúria, sendo identificada massa retroperitoneal com consequente ressecção da mesma e realização de estudos histológicos, evidenciando sarcoma de células fusiformes de alto grau. Conclusão: As lesões retroperitoneais são achados raros e representam um desafio terapêutico pois na maioria das vezes os pacientes se apresentam assintomáticos ou com sintomas inespecíficos.
Altered gut microbiota is associated with feeding intolerance in preterm infants
Authors: Hu Xiaoyan , Chang Yanmei , Wang Zijing , Bao Wenting , Li Zailing
Published: April 2021

Background. Feeding intolerance (FI) is a common complication that may cause great harm to preterm infants. The mechanism of FI remains unclear, but probiotics may help prevent and alleviate its symptoms. We hypothesized that the alteration in gut microbiota may be associated with the development of FI. Our study aimed to investigate the association between gut microbiota and FI in preterm infants.
Methods. Ninety-seven preterm infants were divided into the FI group (N=42) and the feeding tolerance (FT) group (N=55) depending on whether the infants were diagnosed with FI. The fecal samples of each infant were collected on the 7th day after birth. Fecal microbiota was analyzed by 16S rRNA sequencing. Plasma motilin were detected on day-1, 7, 14, and 21.
Results. The microbial diversity of the FI group was significantly lower than that of the FT group. The abundance levels of phylum Proteobacteria, class Gammaproteobacteria, genera such as Escherichia/Shigella were higher in the FI group than in the FT group. The abundance levels of phylum Firmicutes, class Negativicutes, and genus Veillonella were higher in the FT group than in the FI group. The motilin levels on days 7 and 14 were negatively correlated with the FI-enriched genera Planomicrobium and Vibrio, respectively. Our study also found gut microbiota was correlated with FI clinical characteristics, including gestational age, birth weight, age of FI diagnosis, age of FI disappearance, and FI duration.
Conclusions. Altered gut microbiota is associated with FI in preterm infants. FI cases typically have lower microbial diversity, a decreased abundance of beneficial bacteria, and an increased abundance of pathogenic bacteria. Gut microbiota is correlated with the clinical characteristics of FI. The decrease in motilin secretion caused by some bacteria may lead to the occurrence of FI.
The assesment of prothrombotic potential using thrombin generation assay in pediatric patients with nephrotic syndrome: preliminary study
Authors: Soyaltın Eren , Ay Yılmaz , Serdaroğlu Erkin , Vergin Raziye Canan
Published: April 2021

Background. Nephrotic syndrome (NS) is a common kidney disease associated with an increased risk of thrombotic events. The aim of this study was to assess the prothrombotic potential of patients with NS using the thrombin generation assay (TGA).
Methods. A total of 35 patients with NS, who were followed in the Division of Pediatric Nephrology in Behcet Uz Children`s Hospital, were included in the study. After the patients with Steroid Resistant NS (n:3) were excluded, 32 patients in total were evaluated for TGA. Patients were primarily classified according to their response to corticosteroid therapy. The control group consisted of 34 healthy volunteers with similar gender and age distribution to the patients. Blood urine nitrogen, creatinine, albumin, triglyceride, cholesterol, 24-hour proteinuria, platelets, erythrocyte sedimentation rate, C-reactive protein and thrombin generation values in activation and remission period of NS were compared. Moreover, TGA values of the patients in their remission period were compared with the values of those in the control group.
Results. Endogenous thrombin potential (ETP) and peak thrombin levels were significantly higher in the activation period than remission period of NS. Additionally, after the patients achieved remission, their ETP was still higher than the control group. There was a negative correlation between both ETP and peak thrombin levels of patients with serum albumin, whereas a significant positive correlation was detected with platelet levels. Thromboembolic events were not observed in any of the patients during follow-up.
Conclusions. Nephrotic syndrome is strongly associated with hypercoagulopathy as assessed by TGA during active NS. The present study reinforces the usefulness of TGA as a marker of hypercoagulability in pediatric patients with NS. Further studies are needed in this regard.
Rare presentation of levamisole-induced leukoencephalopathy in a pediatric patient: seizure
Authors: Paketçi Cem , Okur Derya , Hız Semra , Yiş Uluç
Published: April 2021

Background. Levamisole is an imidazole derivative used in the treatment of various cancers, dermatological diseases, and parasitosis. Illegal use of levamisole by mixing it with cocaine in order to increase the psychotropic effects has also increased in recent years. Leukoencephalopathy is one of levamisole`s most prominent neurological side effects.
Case. Here we present the clinical, laboratory, imaging findings, treatment, and follow-up information of a 12-year-old girl who presented with seizures due to levamisole, which was prescribed to treat vitiligo.
Conclusion. Levamisole-induced leukoencephalopathy should be considered in the differential diagnosis of demyelinating diseases, the neurotoxic effects of the drug should be well understood, and treatment should be initiated as soon as possible.
The role of plasma exchange in acute liver failure of autoimmune etiology
Authors: Gökçe Selim , Çermik Banu Bal , Kutlu Nurettin Onur , Ocak İlhan
Published: April 2021

Background. Autoimmune hepatitis (AIH) is characterized by increased immunoglobulin G (IgG) levels, the presence of autoantibodies, and various degrees of lymphocyte predominant inflammation and fibrosis histologically. Immunosuppressive therapy induces remission in approximately 80% of those affected. However, liver transplantation is indicated in patients with acute liver failure with encephalopathy at presentation. Liver supporting systems, including plasma exchange (PE) allow bridging patients to transplantation or spontaneous recovery in the setting of liver failure. The role of these systems has not been assessed in children with liver failure of autoimmune etiology.
Case. Herein, we report three cases of AIH with fulminant presentation, with marked symptom resolution with PE as an adjunct therapeutic option to immunosuppressive treatment.
Conclusion. In the setting of AIH, PE may have a special therapeutic role by removing autoantibodies and cytokines, therefore preventing further liver damage and decompensation, and allowing time for recovery.