bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolution of Analytical Approaches in the Study of Innovative Communities
Authors:   Institute of Industrial Economics of the NAS of Ukraine, Petrova I.
Published: December 2023

The evolution of analytical approaches in research and development of the theory of innovative communities is considered. The analysis of the structure and dynamics of scientific research of innovative communities was carried out on the basis of the Scopus database. Bibliometric analysis and visualization using the VOSviewer program are important tools for understanding changes in the thematic focus of scientific research over time. With the help of the program, five research clusters were identified based on the thematic proximity of terms and analyzed which topics and directions of research were relevant at different stages of the time period. It was found that the evolution of analytical approaches in the study of innovative communities at the level of territories has progressed from the analysis of the individual level to network, system, ecosystem and ecological approaches. A clear evolution of analytical approaches can be seen in the research and development of the theory of innovative communities. Innovative communities focused on the development and implementation of innovations are considered with increasing depth and complexity. At the first stage, researchers focused on considering innovative communities as a set of individual individuals and enterprises, where the main emphasis is on the innovative efforts of individual participants and their contribution to the development of innovations. The next stage was the transition to a network approach, where innovative communities were considered as networks of interaction between participants, their communications and resource exchange. This is followed by a systemic approach, which allowed us to view innovation communities as systems with interdependent components such as culture, institutions, policies, infrastructure and human capital. At the current stage, the ecosystem approach to understanding innovation communities dominates, where they are considered as complex adaptive systems interacting with different innovation ecosystems with a wider range of participants. If the system approach is more focused on the internal aspects of innovation communities, while the ecosystem approach takes into account the larger external context and interaction of innovation communities with other entities of innovation ecosystems. In addition, an ecological approach to the interpretation of the concept of «innovative communities» is also developing in parallel, which contributes to sustainable development and nature conservation, and is of great importance in the modern world, where environmental protection is a critically important task.
Economic and Legal Mechanisms of Regulation of Foreign Economic Activity of a Processing Enterprise
Authors:   Institute of Industrial Economics of the NAS of Ukraine, Lukianov A.
Published: December 2023

The article examines the economic and legal aspects of regulating the foreign economic activity of processing enterprises in Ukraine. An overview of economic factors influencing the foreign economic activity of processing enterprises is presented. The author examines the influence of the economic and legal mechanisms of regulation of foreign trade on the competitiveness of the products of processing enterprises on international markets. A review of the special regime of export support during martial law was made.
Anticipatory Management as an Effective Concept for the Development and Implementation of Ukraine's Post-War Recovery Policy
Authors:   State Institution Luhansk Taras Shevchenko National University, Kolosov A. , Chebotarov Iе. ,   State Institution Luhansk Taras Shevchenko National University
Published: December 2023

The question of the relevance and objective necessity of introducing anticipatory management in the activities of enterprises and other entities as a concept aimed at predicting and early response to external manifestations of a threatening nature in the conditions of increasing uncertainty of processes in the market and in society in general is considered. The general content of these issues was considered with a projection on the problematics of developing and implementing the post-war recovery policy of Ukraine. The objective need for the concept of anticipatory management is explained by the fact that society has fully entered a stage of development characterized by the predominance of unpredictability and chaotic manifestations of market and social processes over consumer-producer relations in the market, which will fully reflect the state of the economy in the process of Ukraine's Post-War Recovery. The problem of advancing anticipatory management to managerial practice is connected with the need to develop tools and technology for its application. In the system of monitoring and analysis of the state of enterprise activity, it is necessary to introduce the application of the category of the general indicator of enterprise activity, capable of reacting most sensitively to manifestations of external factors of a threatening nature. In order to observe threatening phenomena in the environment of the functioning of enterprises, it is necessary to establish their weak signals as early predictors of the emergence of threats in the future, as well as the expected duration of the process of their accumulation up to their maximum possible value, the achievement of which leads to significant losses of the enterprise, which can be considered as a state of its crisis, and even catastrophe - in case of forced suspension of the enterprise activity. A crucial component of the implementation of the anticipatory approach is the introduction of the concept and determination in time of the bifurcation point, that is, the extreme moment of the adoption of anti-crisis measures, the effect of which manages to prevent the development of a crisis in the enterprise. It is schematically shown that, given the data on the duration of the process of introducing anti-crisis measures, the bifurcation point on the time axis is determined by delaying the time of the introduction of anti-crisis measures to the left from the expected moment of the crisis.
Who and how will revive Ukraine
Authors:   Academy of Economic Sciences of Ukraine, Bilopolskyі M.
Published: December 2023

A critical analysis and review of the state of Ukraine's economy during the years of independence was made. The impact of foreign consultants and advisors is analyzed. A conclusion was made about the ineffectiveness of the political decisions made. Some ways to improve the current state are proposed.
Accounting and Analytical Support for Crisis Management of Agricultural Enterprises on the Basis of Budgeting
Authors:   Central Ukrainian National Technical University, Zhovnovach R. , Kovalov D. ,   Central Ukrainian National Technical University, Burlaka V. ,   SHEI "Pryazovskyi State Technical University"
Published: December 2023

The article is dedicated to investigating the peculiarities of organizing the accounting and analytical support for crisis management of agricultural enterprises based on budgeting principles. It is noted that due to the negative impact of the state of war, the agricultural sector has suffered significant losses, and agricultural enterprises have faced numerous challenges that threaten their economic security. The necessity of continuous monitoring of the most important accounting objects of enterprises, taking into account quarterly changes, and implementing preventive measures based on an effective accounting and analytical system, which is the key to efficient crisis management of agricultural enterprises, is substantiated. A methodical approach to forming the organization of accounting and analytical support for crisis management of enterprises based on budgeting is presented. This approach is capable of providing management with the necessary information to make informed decisions to prevent a crisis state and develop measures in line with modern crisis management requirements through the identification of future events, the state of the enterprise, risks, and crisis threats. Based on this approach, the budgeting functions in the accounting and analytical support of crisis management of enterprises are delineated. Recommendations for developing budgets for agricultural enterprises, taking into account the specific features of their production activities, are provided. The desired effect of implementing the proposed accounting and analytical support for crisis management of agricultural enterprises based on budgeting principles should manifest itself in ensuring timely identification of risks and signals of a likely crisis state, the causes of its occurrence, informational support for contemporary crisis decisions, and the promotion of the development of effective strategies and measures to preserve the sustainability of agricultural enterprises in the agricultural sector as a whole.
Overview of Modern Approaches to the Formation of the Budget Management System of the Enterprise
Authors:   LLC ", Chupryna Yu. ,   Technical University ",   Metinvest Polytechnic"
Published: December 2023

The article is devoted to a review of modern approaches to the formation of the enterprise budget management system. The article examines the essence of the concept of "budgeting", establishes the main stages and aspects of enterprise budget management. In the article, it is proposed to consider a complex resource management system of the enterprise under budgeting, which is aimed at achieving planned indicators and effective control over the receipt and expenditure of funds. It was determined that the main goal of such a system is to ensure management efficiency and help make effective management decisions to achieve the planned strategic goals of the enterprise. To increase the visibility and efficiency of this system, a visualization of the budgeting system formation procedure is presented in the form of a model built on the Ramus platform in the IDF0 notation (modeling language). It was determined that an effective budgeting system (as an important component of successful management of enterprises) is a dynamic system that is constantly developing and therefore it is advisable to review, adjust and improve it, taking into account the opportunities, priorities, needs and specifics of each company. The need to look for new ways of increasing the efficiency of cost management and to implement digitalization, forecasting and modeling tools in the budgeting system is substantiated. The purpose of the article is to analyze the possibilities of forming an effective enterprise budgeting system based on the analysis of modern approaches to its formation and to determine the possibilities of its successful implementation for Ukrainian companies. The author considers the main trends and challenges that influenced the formation of an effective budgeting system. In particular, the role of IT development, business analytics automation technologies and their impact on the formation of an effective budgeting system are considered. The article draws attention to the fact that for the successful implementation of the budgeting system, it is worth using a modeling toolkit, which allows enterprises to get a better visualization of existing processes and opportunities for their improvement, to establish cooperation and communication, and to improve the data collection and analysis system. The scientific novelty of this article lies in the fact that the recommendations and conclusions provided by the author can be useful for companies wishing to improve their own budgeting systems. In general, this article is useful for those who want to learn more about the budgeting system in business.
Methodical Approach to Assessment of the Stability of Energy Systems Based on a Composite Indicator
Authors:   Institute of Industrial Economics of the NAS of Ukraine, Amosha A. , Mykytenko V. ,   Institute of Industrial Economics of the NAS of Ukraine
Published: December 2023

The article proposes to use a quantitative methodical approach for assessing the economic sustainability of energy systems with elements of distributed generation (DG) (its basis is a set of model solutions for tasks related to the reproduction and assessment of multidirectional consequences of the implementation of energy systems with elements of distributed generation) according to a composite indicator calculated according to a single evaluation criterion, recognized as the most significant, technical and economic, institutional and social external effects. The implementation of the methodological approach involves the implementation of econometric and economic-statistical procedures in four blocks. And, namely, the calculation of: І) the generalized integral indicator taking into account technical and economic external effects and key aspects of the functioning of power systems according to the six-stage algorithm; ІІ) a generalized integral indicator taking into account the institutional external effects of the operation of power systems in six stages; ІІІ) a generalized integral indicator for taking into account social effects in six stages; IV) composite indicator of economic sustainability of energy systems with elements of distributed generation – according to the algorithm in three stages. The significant advantages of the developed methodological approach have been proved, in particular, the plane of objectivity and comparability, flexibility and adaptability, taking into account the relationships between the most important factors, etc.
Central line-associated bloodstream infection related with umbilical vein catheterization and peripherally inserted central catheter in preterm infants: a meta-analysis and systematic review
Authors: Sandinirwan Indra , Leo Henry , Muslim Bani , Hasanah  , Karina Permata Putri
Published: December 2023

BACKGROUND Central line-associated bloodstream infection (CLABSI) is a serious complication in preterm infants undergoing catheterization, including umbilical vein catheterization (UVC) and peripherally inserted central catheter (PICC) placement. This study aimed to compare the occurrence rate of CLABSI in preterm infants associated with UVC and PICC.

METHODS We conducted a systematic review and meta-analysis of studies published from 2000 to 2023 using a random effects model from 3 databases (PubMed, ScienceDirect, and Google Scholar). This study was registered with PROSPERO (CRD42023416471).

RESULTS Of 10 articles included in the systematic review, 2 were randomized controlled trials, 3 were prospective studies, and the rest were retrospective. A total of 3,962 UVCs and 2,922 PICCs were incorporated in the meta-analysis. The incidence rate of CLABSI in the UVC group was lower than that in the PICC group (1.23 versus 3.03 per 1,000 catheter days). However, the odds of developing CLABSI for infants with a UVC compared to those with a PICC were not statistically significant (odds ratio: 0.88, 95% confidence interval: 0.54–1.42).

CONCLUSIONS UVCs had a lower incidence rate of CLABSI than PICCs. Therefore, additional prospective studies are required to confirm these results.
Outward foreign direct investment and GVC position of manufacturing industry: A perspective on China’s general trade and processing trade structure
Authors: Ren Fei , Le Dong , Hu Ziyu
Published: December 2023

Depending on the trading modes, the effect of Outward Foreign Direct Investment (OFDI) on the manufacturing industry’s position within the global value chain (GVC) may differ considerably. This paper examines the GVC position of China’s manufacturing industry from 2003 to 2018, specifically focusing on the general trade and processing trade. Drawing upon this premise, this paper analyzes the effect and mechanism by which OFDI influences the GVC position of China’s manufacturing industry. The result demonstrates that: (1) China’s processing trade manufacturing industry has a much lower GVC position than general trade manufacturing industry. The GVC position of China’s general trade manufacturing industry rose from 2.76 to 2.90 from 2003 to 2018, while processing trade manufacturing industry remained around 1.93. (2) OFDI boosts the GVC position of general trade manufacturing industry through facilitating reverse technology spillover, inducing industry structure upgrading, and enabling export scale expansion. (3) OFDI hinders the GVC position growth of processing trade manufacturing industry. The research findings offer theoretical backing for China to develop OFDI strategies that are tailored to different trading modes within the new framework of dual circulation. These strategies aim to facilitate the transformation and advancement of the manufacturing industry, as well as the growth of the GVC position.
Does ESG privilege climate action over social and governance issues? A content analysis of BlackRock CEO Larry Fink’s annual letters
Authors: Mrchkovska Nela , Dolšak Nives , Prakash Aseem
Published: December 2023

Milton Friedman famously argued that the social responsibility of business is to maximize shareholder wealth. Friedman’s view is challenged by the proponents of corporate social responsibility who suggest that firms should consider the interests of all stakeholders, and not just shareholders. Following the stakeholder approach, BlackRock’s CEO Larry Fink has made the case that firms should use the ESG (environmental, social, and governance) metric to evaluate their performance as opposed to short-term profit maximization. Fink employs his annual “Dear CEO” letters as a platform to outline his views on ESG. While these letters focus on all three ESG dimensions, the media tends to portray Fink as a climate advocate. We examined the texts of the ten letters Fink has published since 2012 to assess the extent to which Fink focused on climate issues. We found that Fink emphasized the climate dimension over social and governance dimensions only in two letters (2020 and 2022), which suggests that the thrust of Fink’s letters differs from how the media frames them. Broadly, our paper suggests that norm advocates sometimes cannot fully control how their advocated norm is interpreted and framed. Limiting ESG to climate issues has implications for its business acceptability. Specifically, this framing links business incentives to adopt ESG to the policy salience of climate issues as well as the fortunes of both the fossil fuel industry and the renewable energy sector. Second, if businesses face a legitimacy crisis from governance shortfalls or inadequate social performance, ESG will serve as a less effective tool in alleviating stakeholder concerns.
BIBLICAL HISTORICISM: SOME APPROACHES TO UNDERSTANDING IN THE RUSSIAN CULTURE OF THE XIX CENTURY
Authors: Nekhvyadovich Larisa I.
Published: December 2023

The article studies the specifics of understanding biblical historicism in the Russian culture of the XIX century from the perspective of the Orthodox Christian worldview, notes the role of religion, the texts of Holy Scripture on the ideological and artistic dramaturgy of works. It is established that there is no general approach in social and humanitarian knowledge that would allow determining the forms and results of the reception of this phenomenon in art. The purpose of the article is to illustrate the thesis that in Russian culture biblical historicism follows from the perception of history as a drama of human relations with the Creator. The historical path of the sacred relationship between God and man is presented as a historical event about the exit of God to man and the ascent of man to God. The factors of formation of ideas about the Holy Scripture in Russia are considered. It is noted that the peculiarity of the situation was that the XIX century was a time of professionalization of historical research. However, it is during this period that the difference is determined.
VALUE BASES OF FORMATION AND STRENGTHENING OF THE ALL-RUSSIAN IDENTITY IN THE PERCEPTIONS OF YOUNG PEOPLE
Authors: Shaikhislamov Rafael B. , Asadullina Guzelia R. , Sadretdinova Evellina V.
Published: December 2023

The article presents some results of the author's sociological research on the problems of determining the value bases for the formation and strengthening of the all-Russian identity in the perceptions of young people, conducted within the framework of the project "Youth in Interethnic Communications: Intolerance, Tolerance, Dialogue" in 2020, 2021 and 2022. The focus of this paper is the analysis of the axiological foundations of the national idea as the basis of all-Russian identity in the assessments of young people aged 16-21. It has been substantiated that young people's ideas about national goals reflect both interests directly related to the life of young people themselves (education, living conditions, etc.) and national interests (ecology, health, eradication of corruption, friendship of the country's peoples, etc.). It was revealed that the majority of young people, regardless of gender and age, place (urban/rural) and region of residence, realize the need for the existence of national ideas that integrate Russians, and in general positively assess the possibility of social integration. The leading ideas-integrators were analyzed, including terminal values: health, decent and comfortable life, as well as values symbolizing the most important social problems of Russian society: property stratification and inequality, poverty, education, corruption. Gender and regional differences in young people's assessments of the importance of integrative values for strengthening the all-Russian identity were characterized. The integrative potential of young people was assessed. The article reveals the peculiarities of young people's attitude to the national goals broadcast by the state, as well as the prospects and the degree of social subjectivity of young people in the context of solving the problems of social integration.
SOCIAL-PROFESSIONAL ORIENTATION OF SCHOOLCHILDREN IN THE REPUBLICS OF SOUTH SIBERIA
Authors: Oidup Tana M. , Troshkina Irina N. , Dilekova Suraya D.
Published: December 2023

The article considers the results of the sociological survey of 2023 concerning the choice of future profession among school-graduates of three Russian regions. The empirical base of the study was formed by the survey materials of the 9th and the 11th grade schoolchildren. The survey was carried out using the questionnaire method in the republics of Tyva, Altai and Khakassia (2522 people, multistage sampling). The analysis of the question concerning the influence of nationality on the social-professional orientations among school-graduates from the republics of Altai, Tuva and Khakassia did not show any significant differences. But there were differences caused by the peculiarities of the social environment and specifics of social-economic development in the mentioned republics. The choice of future profession is determined by the social environment, which differs in the three regions by its social-economic features in each other. The authors understand the concept «social-professional orientation» as the decision, as a social action that a school-graduate performs for achieving his or her goal – getting education and profession. The study of questionnaires responses indicates that the majority of the school-graduates connects the choice of their future profession with a primarily affective action, next with value-rational social action; in the third place – purposeful rational action, in the last – traditional action. Special attention is paid to the issue of choosing a region for a future place of work, which reveals the desire of schoolchildren: to stay to work in their region replenishing the human capital of their native republic, or to move to another region and organize labor activities there. We tried to find out whether social-professional orientations correspond to the real needs of the regional economy using a sociological survey among the graduates of the republican schools within three mentioned regions.
Designing for social change to create shared value innovation – Should all firms pursue shared value innovation? It depends
Authors: Riess Victoria
Published: December 2023

Every firm in the world can change how it thinks about creating value in the world. If the primary bottom-line of firms changes to a mix of social and financial factors, then their businesses will be able to deliver a more sustainable and equitable growth for all stakeholders.
IoT analytics and smart energy – How I assessed the UK Electric Vehicle charging market opportunity for a leading service monitoring company for connected devices
Authors: Riess Victoria
Published: December 2023

In this consulting project, I assessed the growth opportunity in the UK Electric Vehicle (EV) charging market for the CEO of a Europe-wide leading service monitoring company for connected devices. I analysed the market opportunities in the UK EV charging market, assessed the customer needs and pain points, and derived potential strategies in the IoT analytics and smart energy market.
Language is Politics
Authors: Jeon Jaeho
Published: December 2023

Language is an intimate process that virtually all humans can understand, produce, and/or engage with cognitively. Consciously or unconsciously and for any reason, humans constantly use language, whether for connecting with others or managing inner thinking such as making plans, composing narratives of one’s experiences, creating art, or simply making sense of any phenomena, as well as using it as a tool to gain advantage. However, despite our constant and intimate engagement with it, language has always been an enigma, eluding our complete understanding. Nevertheless, given the close relationship between using language and being human, our quest to understand language is intrinsically tied to fundamental questions about humanity itself, which may lead to various misconceptions, such as the deeply ingrained perception that the complexity of human language separates our species from the rest of the natural world.
Trayectos estéticos: caminar, oír, fotografiar y relatar la experiencia educativa
Authors: Pérez Rincón Adriana Rocío
Published: December 2023

En este artículo se presentan los principales resultados de la investigación doctoral “Trayectos estéticos-educativos de estudiantes universitarios y niños y niñas en El Charquito y El Recreo: un análisis desde las prácticas educativas de la Licenciatura en Artes Visuales (LAV) de la Universidad Pedagógica Nacional (UPN)”, cuyo objetivo principal consistió en comprender la experiencia de la práctica educativa y sus posibilidades para articular narrativas que amplíen la mirada sobre la educación artística visual a través de la identificación de derroteros que marcan el propio ejercicio educativo desde la dimensión dialógica, la hospitalidad, las prácticas del caminar, fotografiar, oír y relatar; experiencias educativas que son significativas cuando son relatadas desde una implicación intersubjetiva. Para cumplir este propósito se emplearon estrategias de etnografía multisituada, autoetnografía interpretativa y (re)colección de imágenes fotográficas que permitieron recobrar la experiencia y atender a las relaciones dinámicas entre los sujetos y contextos diversos que caracterizaron a la práctica educativa. Los resultados y conclusiones que arrojó esta investigación dan cuenta de la consolidación de una serie de escrituras que recurren a la imaginación, la oralidad y el juego como formas que potencian la constitución de subjetividades. Asimismo, se proponen algunos derroteros para repensar y reescribir las prácticas educativas atendiendo a los trayectos de vida.
Posicionamiento de mediadoras escolares de lectura. La Biblocleta como dispositivo didáctico de mediación
Authors: Torres Cárdenas Ángela Carolina , Chacón Chacón Adriana , Combariza Salamanca Luisa Fernanda
Published: December 2023

El artículo da cuenta de una investigación que apunta a comprender de qué manera las prácticas de mediación didáctica de la lectura contribuyen al fortalecimiento de los procesos de formación docente y, por ende, al posicionamiento de las mediadoras escolares, al tiempo que favorecen la resignificación de la biblioteca escolar. La metodología se circunscribe en el enfoque de investigación-acción participativa (IAP), cuya naturaleza dialéctica y transformadora dinamizó un trabajo colectivo, colaborativo y horizontal, que derivó en la creación del grupo de estudio denominado “Semillero LEO: el arte de lecturar”, y en el diseño de una propuesta de mediación lectora apoyada en un dispositivo didáctico de origen barrial: La Biblocleta, el cual puso de manifiesto la necesidad del intercambio de saberes entre las experiencias comunitarias y las académicas. Entre los resultados se cuentan, en el plano teórico, la propuesta de una estructura conceptual que permitió explorar la biografía lectora, aprender a valorar libros y entender el acceso a la lectura como un derecho cultural, y en el plano de la praxis, la configuración de una comunidad de aprendizaje que logró institucionalizar al Semillero LEO, el cual liderará un centro de interés desde la línea de investigación de lectura para los ciclos intermedio y profesional de una escuela normalista. En conclusión, además de posicionar maestras normalistas mediadoras de lectura, esta investigación abrió nuevos caminos de estudio para continuar movilizando las prácticas lectoras que conduzcan, entre otras cosas, a reactivar la biblioteca escolar como un espacio de libre acceso y puertas abiertas.
La vida tatuada y la educación literaria
Authors: Quitián Bernal Sandra Patricia , Montoya Castillo Mario
Published: December 2023

Si la ‘vivencia’ transita en el circuito que vincula realidad, reflexión y comprensión, podríamos sostener un hilo conductor, a propósito de lo que encarna la educación literaria (Colomer, 2010), desde cuestiones vitales como a la vida cotidiana, las experiencias y vivencias personales que hacen posible habitar los espacios de la lectura y escritura creativas del aula. Esta apuesta política y educativa no es otra cosa que privilegiar las ontologías del juego, los intercambios poéticos, la curiosidad, la exploración de sí mismo, del otro y del mundo; es mantener vivo el sueño de libertad y aprender a tejer con lo inesperado (cf. Petit, 2010).
Presentación
Authors: Jurado Valencia Fabio de Jesús , Guzmán Simón Fernando , Bombini Gustavo
Published: December 2023

Las páginas de este número especial de la revista Enunciación relacionan dos tópicos que no siempre han transitado juntos a lo largo de la historia. Aunque se pueden rastrear ejemplos tempranos de literatura didáctica ya desde el siglo XII (como señalan algunos autores con el caso de El romancero o Los milagros de Nuestra Señora, de Gonzalo de Berceo), no ha ocurrido así con la pedagogía. De esta, hemos indagado algunas reflexiones sobre el aprendizaje de la lectura y la escritura en maestros de los siglos XVI y XVII (Gómez Camacho, 2019). Sin embargo, es desde épocas recientes que se ha planteado un marco sistémico de relación entre la literatura y la pedagogía para estudiar los procesos clave del aprendizaje y la enseñanza de la lectura, en general, y de la literaria, en particular.
In Silico and In Vitro Study Selaginella doederleinii Herb Extract as An Antineoplastic on MCF-7 Cells and Formulation Development of Nano Effervescent Granule
Authors: Anggraini Chaessy Yori , Kusumaningtyas Triana Arum , Juniananda Melisa , Ningrum Dhecella Winy Cintya , Febriansah Rifki , Hermawansyah Adi
Published: December 2023

Breast cancer, the leading cause of cancer-related deaths in women with 685,000 deaths in 2020. Exploring natural compounds with minimal side effects has emerged as a potential treatment. However, utilizing natural substances faces challenges, such as poor bioavailability, requiring technologies like nanotechnology to enhance absorption. This study focuses on evaluating Ethanol Extract of Selaginella doederleinii (EESD) as an anticancer against MCF-7, both in silico, in vitro methode and develop a formulation of EESD nanoparticle effervescent granules. This study commenced with extraction, Gas Chromatography-Mass Spectrometry (GC-MS) identification, in silico studies, namely bioinformatics and molecular docking, 3-(4,-5-dimethylthiazo-2-yl)-2,5-diphenyltetrazolium bromide (MTT) Assay tests on MCF-7, and the formulation of nanoparticle preparations. EESD was extracted using the maceration method, resulting in an extract weighing 103.5 grams with a 6.9% yield. GC-MS identified three major compounds—cyclopentadecanoic, 2-hydroxy; hexadecanoic acid; and 9-octadecanoid, methyl ester. Bioinformatics revealed interactions with specific protein targets, and molecular docking indicated hexadecanoic acid's superior binding to TP53, surpassing paclitaxel at -8.7 kcal/mol. This suggests its potential to modulate TP53, impacting P53's role in impeding cancer cell growth. EESD exhibited an IC50 of 215μg/mL, signifying moderate cytotoxicity. In formulating nanoparticle effervescent granules, five formulas were transformed into nanoparticles and underwent organoleptic, pH, granule dissolution, and water content evaluations. Formula I is the formula that best meets the criteria with a pH of 6.55, granule dissolution <5 minutes, and water content <4%. The research results indicate that EESD shows anticancer activity against MCF-7 and this study has successfully developed a formula of nanoparticle from EESD in effervescent granule form.Keywords: Selaginella doederleinii, breast cancer, co-Cemotheraphy, MCF-7 Cell, in silico.
ETNOSENTRİZM BAĞLAMINDAKİ ÖTEKİLEŞTİRİLME SORUNSALI ÇERÇEVESİNDE SANATÇININ KİMLİK YARATIMI
Authors: KILINÇ Sevgi
Published: December 2023

Toplum içerisindeki sosyal gruplar farklı bağlamlarda ve farklı zamanlarda ötekileştirilmeye maruz kalabilmektedir. Etnosentrizm ötekileştirmeyi etnik köken üzerinden tanımlayan sosyolojik bir kavramdır. Bu kavram çerçevesinde gelişen fikirler siyasi anlaşmazlıklar, terörizm, savaş ve soykırıma kadar varabilecek tehlikeli sonuçlar barındırmaktadır. Postmodern dönemin çoğulcu yaklaşımıyla birlikte etnik köken, ırk, kültürel farklar ve cinsiyet farklılıklarının ayrıştırıcı birer unsur olmadıkları aksine, çeşitliliğin toplumu zenginleştirmeye katkı sağladığı kabul edilmiştir. Araştırmanın kavramsal altyapısı için; sanat, sosyoloji, felsefe ve psikoloji gibi birçok disiplinde literatür taramaları yapılmış ilgili kısımlar eklenmiştir. Çalışmanın amacı kapsamında etnosentrizm bağlamındaki ötekileştirme çerçevesinde beş sanatçının bu doğrultuda yaratılmış çalışmalarına yer verilmiştir. Kendi etnik kökenleri doğrultusundaki ötekileştirilme durumlarını eserlerine yansıtan sanatçıların yaratımlarını konu alan bu araştırmanın plastik sanatlar alanında araştırmalar ve üretimler yapan kişilere katkı sağlayacağı düşünülmektedir.
Cardiac Abnormalities in Refractory Status Epilepticus-an Exploratory Study
Authors: Saroha Deepika , Panda Samhita , Deora Surender , Mohammed Sadik
Published: December 2023

Background and Purpose: Cardiac abnormalities have been reported during ongoing seizures and refractory status epilepticus (RSE). Reduced heart rate variability (HRV) and cardiac arrhythmias may contribute to sudden unexpected death in epilepsy. We sought to explore the utility of electrocardiographic and echocardiographic changes in patients with RSE prognosis and functional outcome.Methods: Patients of RSE underwent electrocardiogram (ECG), holter, troponin-I (Trop I), N-terminal prohormone of brain natriuretic peptide (NT-proBNP), and 2-dimensional echocardiogram (2D Echo) along with continuous electroencephalogram in first 24 hours and admission. Heart rate changes/arrhythmias, corrected QT interval (QTc) and HRV, ventricular dysfunction or regional motion wall abnormality were studied on 2D Echo. These parameters were also at baseline, at discharge or death and 30 days post discharge.Results: This prospective observational study conducted over 18 months enrolled 20 patients with RSE, fulfilling the inclusion criteria. Mean age was 47.75±17.2 years with male: female ratio of 1:1. Mean time to presentation from seizure onset was 8.80±7.024 hours. Central nervous system infection (35.0%), autoimmune encephalitis (20.0%) and cerebrovascular disease (20.0%) were the common etiologies. Amongst cardiac injury markers, cardiac enzymes and QTc prolongation were the commonest abnormalities in RSE. Both reduced HRV and presence of cardiac injury markers had significant correlation with poor outcome along with poor Glasgow coma scale (GCS) and modified Rankin scale (mRS) at presentation, and presence of non convulsive status epilepticus (NCSE).Conclusions: Presence of poor GCS, poor mRS, markers of cardiac injury, reduced HRV and occurrence of NCSE have a consistent correlation with mortality and poor clinical outcome. Therefore, routine assessment of cardiac abnormalities using affordable, easily accessible and non-invasive tools such as ECG, 2D Echo, holter NT-proBNP and Trop I is recommended in RSE patients.
Analysis of Deficits in Total Knee Replacement Cases at Siti Fatimah Hospital, South Sumatera
Authors: Putra Ramadhan Ananditia , Simanungkalit Ian Ervan , Nugraha Muhammad Ilham Satya
Published: December 2023

Health is one of the basic human needs and is a right for every citizen that is protected by law. The form of the State's efforts in providing health services is by launching the National Health Insurance Program (JKN) through the Social Security Administration Agency. In practice, many cases experience a deficit related to costs incurred by the Hospital and costs obtained through INA-CBG's claims. The purpose of this study was to see if there were any adverse differences in the Total Knee Replacement case carried out at Siti Fatimah Hospital. This research was quantitative, descriptive research in hospital. Data collection was a total of 19 patients suffering from knee Osteoarthritis and who had to do Total Knee Replacement at Siti Fatimah Hospital from 2020-2023. The results of the study found that in every case of Total Knee Replacement the hospital always experienced a deficit. In average national healthcare system only reimbursed half of our cost. Further evaluation of INA-CBGs reimbursement scheme is necessary to ensure hospital to achieve ideal cost recovery when patients are treated.
Hubungan Ketepatan Penulisan Diagnosis Penyakit dengan Keakuratan Kode Diagnosis pada Pasien Rawat Inap di Rumah Sakit
Authors: Suryandari Endang Sri Dewi Hastuti , Rahmadhani Regina Novi , Pitoyo Acmad Zani , Sangkot Hartaty Sarma , Wijaya Avid
Published: December 2023

The accuracy of the disease diagnoses code is determined by the accuracy of writing the diagnoses. The result of observation in 10 inpatient medical record documents at the TNI-AD 05.08.04 Hospital Lawang, 5 documents were found with inaccurate codes (50%) with 3 incorrectly written diagnoses. The purpose of this study was to analyze the effect of the accuracy in writing disease diagnoses to the accuracy of the diagnoses code for inpatients at the TNI-AD 05.08.04 Hospital, Lawang. This methode of research was an analytic observational with a cross-sectional approach. The number of sample analyze were 100 inpatient medical record documents which hospitalitaion from March to August 2022 and using simple random sampling technique by lottery. The accuracy of writing diseases diagnoses of inpatient was an independent variable and the accuracy of the diagnoses code for the inpatient at the TNI-AD 05.08.04 Hospital, Lawang was dependent variable in this study. The results showed the accuracy in writing disease diagnoses was 70% and the accuracy of the disease diagnoses code was 45%. The analytic test with Chi Square showed significantly the effect of accuracy in writing diseases diagnoses to the accuracy of diagnoses code for inpatient at the TNI-AD 05.08.04 Hospital Lawang with a p-value = 0.000 (<0.05). The accuracy in writing diseases diagnoses by doctor that refer to medical terminology of ICD-10 will producted an accurate diagnoses codes.
Mubi-Toram lexicon and Afro-Asiatic IV: Addenda with *b- (Part 2)
Authors: Takács Gábor
Published: December 2023

The paper is another part of a planned longer series designed to step by step reveal the Chadic and wider Afro-Asiatic cognate heritage in the lexical stock of the Mubi-Toram languages which represent the easternmost (26th) group of the vaste Chadic (i.e., 6th) branch of the gigantic Afro-Asiatic family.
Towarzyszenie w rodzinie osobom starszym
Authors: Kochel Jan
Published: December 2023

W artykule zaprezentowano prorodzinne podejście do problemu edukacji i formacji osób starszych. Różne środowiska są zainteresowane tym, co składa się na pozytywne starzenie się, wśród nich jest również rodzina jako pierwsza i fundamentalna „szkoła cnót społecznych” (DWCH 3). Gerontologia jest nauką o starzeniu się i starości, która w ostatnich latach dynamicznie się rozwija, proponując nowe modele edukacyjne pedagogiki kultury (transcendentnej), np. „gerotranscendencji” czy „pedagogiki towarzyszenia”. Warto skonfrontować je ze źródłami biblijnymi i nauczaniem Kościoła na temat współczesnych procesów starzenia się. Istotnym kierunkiem wychowania senioralnego oraz towarzyszenia osobom starszym w rodzinie jest korygowanie negatywnego wyobrażenia o starości oraz ukazywanie jej jako szansy rozwoju intelektualnego, społeczno-kulturowego i duchowego. Stąd pilna potrzeba duszpasterstwa osób w podeszłym wieku we wspólnocie rodzinnej i parafialnej. Wartość wybranej koncepcji polega na pozytywnym, ale i realistycznym podejściu do zaangażowania seniorów. W końcu wszelkie teoretyczne podstawy pedagogii osób starszych mogą zostać rozwiązane i rozwiązania proponowane mogą zostać zweryfikowane na gruncie refleksji gerontologicznej dopiero w bezpośrednim kontakcie z osobami starszymi w rodzinie.
Duszpasterskie towarzyszenie narzeczonym i młodym małżonkom w Kościele katolickim według najnowszego dokumentu Dykasterii ds. Świeckich, Rodziny i Życia na tle dotychczasowej praktyki duszpasterskiej i dokumentów Magisterium
Authors: Gałuszka Paweł , Dej Magdalena
Published: December 2023

Przedmiotem artykułu jest refleksja nad duszpasterskim towarzyszeniem osobom przygotowujących się do zawarcia ślubu w Kościele katolickim proponowanym w najnowszym dokumencie Drogi wtajemniczenia katechumenalnego do życia małżeńskiego z 2023 r. Dokonana ona została na tle dotychczasowych dokumentów Magisterium oraz praktyki duszpasterskiej w zakresie przygotowania do sakramentu małżeństwa na przestrzeni ostatniego stulecia. Dla zrealizowania tak postawionego celu przeprowadzono analizę dokumentów Kościoła powszechnego, a także dokumentów Konferencji Episkopatu Polski odnoszących się do tego zagadnienia, przeanalizowano ponadto wypowiedzi poszczególnych papieży. Sobór Watykański II przyniósł istotną zmianę w spojrzeniu na sakrament małżeństwa. Konsekwencją refleksji soborowej były późniejsze wytyczne dotyczące sposobu przygotowania narzeczonych zawarte w adhortacji Familiaris consortio Jana Pawła II. Najnowszy dokument Dykasterii ds. Świeckich, Rodziny i Życia powstały po publikacji adhortacji Amoris laetitia papieża Franciszka, proponuje zmiany w towarzyszeniu narzeczonym i młodym małżonkom. W myśl założeń tego dokumentu powinno być ono realizowane poprzez drogę wtajemniczenia katechumenalnego, której pierwszym celem jest przybliżenie narzeczonych do Kościoła i rozbudzeniem wiary, a dopiero drugim bezpośrednie przygotowanie do ślubu.
Status prawdziwościowy narracji – perspektywa socjologii (religii), realizmu krytycznego i fenomenologii
Authors: Królikowska Anna M.
Published: December 2023

Przedmiotem badania prezentowanego w artykule jest narracja jako kategoria socjologiczna, zaś celem teoretyczna refleksja nad możliwością ujęcia jej w sposób inny niż w deontologizującej perspektywie postmodernistycznej, który pozwoliłby oceniać status prawdziwościowy narracji obecnych w życiu społecznym. Jako metodę proponuje się rozpatrywanie narracji w świetle realizmu krytycznego. Choć teoria ta dostarcza uzasadnienia i kryteriów sprawdzianu referencji do rzeczywistości, pojawia się też wniosek związany z postawą badacza, który powinien unikać destruującego podejścia do historycznie wytworzonych, kulturowych i sensotwórczych narracji i w tych sytuacjach raczej wybierać perspektywę fenomenologiczną.
Dynamics of an eco-epidemic model with Allee effect in prey and disease in predator
Authors: Kumar Bipin , Sinha Rajesh Kumar
Published: December 2023

In this work, the dynamics of a food chain model with disease in the predator and the Allee effect in the prey have been investigated. The model also incorporates a Holling type-III functional response, accounting for both disease transmission and predation. The existence of equilibria and their stability in the model have also been investigated. The primary objective of this research is to examine the effects of the Allee parameter. Hopf bifurcations are explored about the interior and disease-free equilibrium point, where the Allee is taken as a bifurcation point. In numerical simulation, phase portraits have been used to look into the existence of equilibrium points and their stability. The bifurcation diagrams that have been drawn clearly demonstrate the presence of significant local bifurcations, including Hopf, transcritical, and saddle-node bifurcations. Through the phase portrait, limit cycle, and time series, the stability and oscillatory behaviour of the equilibrium point of the model are investigated. The numerical simulation has been done using MATLAB and Matcont.
IG-YOLOv5-based underwater biological recognition and detection for marine protection
Authors: Huo Jialu , Jiang Qing
Published: December 2023

Underwater biological detection is of great significance to marine protection. However, the traditional target detection techniques have some challenges, such as insufficient feature extraction for small targets and low feature utilization rate. To address these challenges, an underwater biological detection model IG-YOLOv5 based on the idea of feature reuse is proposed. An Improved-Ghost module with feature reuse is designed. The module adds batch normalization operations to the identity mapping branch using the Add operation with feature fusion and the Sigmoid Linear Unit activation function with smoother zeros. The proposed model uses the Improved-Ghost module to reconstruct the CSPDarknet structure of YOLOv5, so as to realize the lightweight and accuracy improvement of the model. In addition, in order to solve the problem of target size and shape change in underwater environment, the optimized loss function is Wise-IoU v3, which is used to evaluate the accuracy and robustness of detection results. The results show that the IG-YOLOv5 model performs well in the 2021URPPC data set, with 0.5 mAP reaching 74.2, 4.3% higher than that of YOLOv5 model, and 2.7 less floating-point operations. In a word, IG-YOLOv5 model has high accuracy and robustness in underwater target detection, and Wise-IoU index can evaluate the quality of target detection results more accurately, which is suitable for underwater robots, underwater monitoring, and other fields and has a practical application value.