bluuebunny/crossref_metadata_2025 huggingface dataset:
Alveolar soft part sarcoma with neural differentiation and aberrant TLE1 expression: A case report
Authors: Gupta Maydhaavi , Neeravari Ashalatha , Chandran Nirmala , Biligi Dayananda S
Published: December 2024

Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor of uncertain histogenesis. It occurs most commonly in deep soft tissues of the lower extremities. Relevant histomorphology and diffuse and strong immunoreactivity of TFE3 has been included in essential diagnostic criteria by WHO Soft tissue and Bone tumors, 5th edition.

A 35 years female presented with recurrent painless posterior right thigh mass which progressed to a size of 15x15cm in 6 months. MRI of the swelling showed T1 isointense and T2 hetrointense lesion with multiple flow voids and few non enhancing areas suggestive of necrosis. Fine needle aspiration cytology showed tight clusters of round to oval tumor cells with moderate cytoplasm. Sections from the cell block revealed tumor cells arranged in an organoid pattern. Individual cells showed a round to oval nucleus with powdery chromatin and abundant eosinophilic to clear cytoplasm. Diagnosis of undifferentiated sarcoma was made. Histopathological examination of the excised lesion showed round to oval shaped cells arranged in nests and alveolar pattern. Individual cells showed mild degree of atypia with a vesicular nucleus, moderate eosinophilic cytoplasm and distinct cell borders. Increased mitoses, prominent vascularity, extensive areas of necrosis and hemorrhage were seen. Immunohistochemistry (IHC) for TFE3, TLE1, synaptophysin and BCL2 was positive and it was negative for pan cytokeratin and S100. Periodic acid‐Schiff stain for intracytoplasmic crystalline structures was negative. Based on the histomorphology and IHC, diagnosis of ASPS was made showing neural differentiation and abberent TLE1 expression. Further studies were suggested for confirmation of the diagnosis.

Accurate diagnosis of ASPS requires trained pathologists and molecular testing to lead the treatment accordingly. This case is presented owing to its overlapping histomorphological and immunohistochemical findings.
A rare case report of primary squamous cell carcinoma of the trachea
Authors: Shah Pragati Atulbhai , Patel Divya Gordhanbhai , Gandhi Minesh , Shah Cherry
Published: December 2024

Primary tracheal tumors are rare in adults and are typically malignant, representing approximately 0.2% of all malignant tumors. The estimated incidence of tracheal cancer is about 0.1 per 1,00,000 people annually. We are presenting a case of 46-year-old woman with chief complaint of midline neck swelling associated with difficulty in breathing at rest. Radiological findings showed focal ill-defined enhancing lesion arising from inferior lobe of thyroid. Bronchoscopy revealed an endotracheal growth partially obstructing the lumen. Biopsy of tissue from intraluminal mass in trachea revealed Moderately differentiated squamous cell carcinoma of trachea. For further evaluation, tracheal resection was performed and sent for histopathological examination confirming our diagnosis of Keratinizing moderately differentiated squamous cell carcinoma and was staged according to Bhattacharya Staging System.
Case report of cytological findings of secretory carcinoma of breast in a 12-year-old girl
Authors: Dhiman Itisha , Jain Chetna
Published: December 2024

Secretory carcinoma of breast (SCB) is a rare form of breast cancer. It is the most commonly seen in children as primary breast cancer. It is seen more commonly in women as compared to men. These tumours were initially seen in children. Many studies have shown that these cancers can occur in adults as well. In this case report, a young (12) year old female patient presented with left sided breast lump. Patient was referred for ultrasound which revealed a benign well circumscribed lesion.

Patient was referred from surgical OPD to department of pathology where she underwent fine needle aspiration cytology (FNAC). Based on cytological findings a provisional diagnosis of secretory carcinoma was made which was confirmed on histopathology.

Despite having lower incidence rates these malignant neoplasms should be kept as an important differential in young patients.
Subretinal neurocysticercosis: A lesser explored manifestation of a fairly common condition
Authors: Sharma Avadh Vihari Lal , Varshney Arpit , Afrose Ruquiya , Gangopadhyay Gourik , Arif Sayeedul Hasan
Published: December 2024

Cysticercosis in humans is the most common parasitic zoonotic diseases worldwide with an estimated prevalence greater than 50 million persons infected. Cysticercosis is the infection caused by the larval form of the cestode tapeworm Taenia solium, also termed as Cysticercosis cellulosae. It is the most common parasitic cerebral infection encountered in worldwide neurosurgical practice. The condition has been estimated to affect nearly 2.5 to 8.3 million people annually accounting for a global burden of 2.8 million disability adjusted life years. Endemic to all continents, the condition is particularly more prevalent in Central and South America, India, Africa and China. In India, the ocular adnexa has been found to be the most common site of neurocysticercosis but the condition is underreported and not diagnosed until full-fledged retinal detachment or blindness sets in. Cysticercosis must be kept in the mind in patients presenting with decreased vision, photophobia, redness of the eye as is notorious for the chronicity.
Double malignancy of prostate and testis: A rare case report
Authors: Kahlon Simranpreet Singh , Gokhroo Sunil
Published: December 2024

Prostate cancer rarely metastasize to testis and it is even rarer to find double malignancy involving prostate and testis. In an unusual case of high grade prostate cancer, intratubular seminoma was found in one of the testis of the patient after both testis were biopsied. He underwent bilateral orchidectomy as part of androgen deprivation therapy for high grade prostate cancer. It is important for physicians to be aware of such surprise.
Length-weight Relationship and Study using RAPD Technique to Determine the Genetic Variation of Yellow Catfish (Mystus nemurus, Valenciennes 1840) in Nong Han lake, Sakon Nakhon Province, Thailand
Authors: Phromthep A. , Prisingkorn W. , Wongmaneeprateep S. , Kumla S. , Doolgindachbaporn S.
Published: December 2024

Background: Yellow catfish, one of Southeast Asia’s most economically significant fish, is found in natural water sources in Thailand. Research on genetic diversity is essential for effective aquatic species management. The purpose was to assess the length-weight relationship (LWR) and genetic diversity of yellow catfish (Mystus nemurus) from Nong Han Lake, Thailand. Methods: 330 samples were collected from ten subpopulations: Ban Tha Rae (n = 31), Don Ang (n = 30), Wat Phon Bok (n = 30), Don Sakhan (n = 32), Don Sao Aey (n = 30), Don Sawan (n = 40), Nguyen Don (n = 32), Lum Nam Phung (n = 40) and Ban Tha Sala (n = 35). Surasawadi floodgate (n = 30). The LWR and feeding intensity were described by the equation W = aTLb and the condition factor (KF) was calculated as KF = 100 W/TLb and RAPD technique was used to evaluate the populations. Result: The results showed b and KF values ranged from 2.7841-3.6942 and (KF) values from 0.1706-2.0943. 102 DNA bands were identified from RAPD with sizes ranging from 200 to 2,500 bp. Polymorphic loci were found in 71.57% to 98.04%. Nei’s gene diversity ranged from 0.24 to 0.36. The genetic distance between reproducible bands of amplified DNA fragments varied from 200 to 2,500 bp. The UPGMA dendrogram of the RAPD-PCR patterns revealed two groups of genetic relationships. The average genetic distance across all samples ranged from 0.020 to 0.245.
Agriculture Drone-A Boon Technology for Foliar Nutrition to Enhance Productivity of Blackgram (Vigna mungo)
Authors: Hemalatha M. , Joseph M. , Vinitha N. , Sowmiya S. , Babu R. Santhosh
Published: December 2024

Background: The current study aimed to evaluate the effect of foliar nutrition of TNAU pulse wonder and polyfeed using an agricultural drone in comparsion with hand spray on black gram growth and yield efficiency. Methods: The field experiment conducted during the summer of 2023 at the VOC Agricultural College and Research Institute, Tamil Nadu Agricultural University, Killikulam. A randomized block design of eight treatments and three replications was used to set up the experiment. The treatments included drone spray with two different concentration of TNAU pulse wonder and Poly feed individually at the rate of 1.0% and 2.0%). Similarly manual spraying of the same product at 1.0% and 2.0% were performed. Result: The results revealed that drone spray of 2% TNAU pulse wonder with spray fluid of 75 L ha-1 using atomizer nozzle recorded higher plant dry matter production (3952 kg ha-1), more LAI (3.54), higher grain (725 kg ha -1) and haulm yield (2935 kg ha -1), with the net return of 25335 Rs.ha-1 and B:C ratio of Rs.2.20 per rupee invested. it was followed by application of Poly feed 2.0% through drone. Manual spray of both TNAU pulse wonder and Poly feed were underperformed in blackgram. Hence, it is concluded that application of 2% TNAU pulse wonder at 30 and 45 DAS through drone could be a viable technology to improve the growth and yield of black gram.
Environmental Sustainability Development in Indonesia Integrating with the Green Economy: a VECM Analysis
Authors: Basri  , Abdullah  , Gunawan Syahrul , Hamid Ahmad Musleh Abdul
Published: December 2024

This study aims to examine and analyze factors that influence sustainable environmental development in Indonesia through the Green Economy policy. The issue of sustainable development is increasingly crucial amidst increasing global emissions that threaten human safety. The green economic development model is suspected to be a development model that prioritizes economic, social, and environmental dimensions to achieve sustainable development in an integral manner. The type of data is a time series with a research period of 1992–2022. The analysis model used is the Vector Error Correction Model (VECM) to analyze the long-term and short-term relationships of the variables agriculture productivity, expected years of schooling, and renewable energy on carbon emissions. The results of the study indicate that there is no long-term relationship between the impact of the green economy, but in the short term, the variables Agriculture Productivity and Expected Years of Schooling affect carbon emissions. The results of this study emphasize the importance of a consistent green economy policy. The government and the private sector can increase investment in the renewable energy sector, allocate resources, and adopt environmentally friendly technologies. In addition, strict environmental regulations and increased education are key to building public awareness of the importance of a green economy and environmental sustainability and creating a culture and lifestyle that support environmentally friendly practices at the individual and community levels.
Siapakah Penduduk Asli Pulau Komodo? Sebuah Kajian Linguistik Historis Komparatif dan Kaitannya dengan Persebaran Islam di Flores
Authors: Kurniawati Rikke , Sanubarianto Salimulloh Tegar , Husnan Lalu Erwan , Hamdiah Magfirotul
Published: December 2024

Komodo is the only local language in Flores where all speakers are Muslim. In addition, the level of difference between this language and the surrounding languages is quite high. This study aims to identify the kinship of the language spoken by the people on Komodo Island and its relation to the spread of Islam in Flores. The approach used is comparative historical linguistics. Data were collected using interview and elicitation techniques using 1090 vocabularies in 12 observation points. The collected data were analyzed using Zikic's dialectometric method that compares the number of cognate vocabulary similarities. The results show that the language spoken by the people in Komodo Island tends to be related to the Mbojo language spoken on Sumbawa Island because it has an average cognate percentage of 43% which means that the two languages are two different dialects of the same language. Other elements that make up the Komodo language are Bajo (26%) and Manggarai (21%). The spread of the Komodo language is linked to the migration of people from the Sultanate of Bima to the western part of Flores Island. The distribution of Komodo speakers has significantly increased the concentration of the Muslim community in West Manggarai Regency.
Bahasa Sebagai Media dalam Adaptasi Sosial Masyarakat Pendatang di Dusun Talangih Kecamatan Waru Pamekasan
Authors: Kusumawati Hesty , Misnawi
Published: December 2024

This research is carried out to find out how language process has become social adaptation medium for immigrants at Dusun Talangih, Waru district of Pamekasan. This research uses qualitative research methods with a descriptive approach. The techniques of data collection used in this study are observation, interview, and documentation. The purpose of this research is to know the process of social adaptation of the immigrant people in Dusun Talangih Waru district of Pamekasan. The results of this study show that immigrant communities have different experiences in their process of adaptation. Some of them said that the process is easy but some others say the contrary. The immigrant communities also have to learn the Madurese language to survive whereever they live in Madura. Then, there are several stages of adaptation they have to fulfil, namely: honeymoon, culture shock, recovery, and adjustment.
Kinetics of formation of individual C1-C5 hydrocarbons during stepwise dry pyrolysis of kerogen from Domanik shale after hydrothermal treatment
Authors: Bushnev Dmitry , Burdelnaya N.
Published: December 2024

The article presents the results of determining the kinetic characteristics of the formation of individual hydrocarbon gases at different stages of artificially increased thermal maturity of the Domanik shale from an Chut River outcrop (Ukhta District). Based on the data of stepwise pyrolysis of residual kerogen isolated from the shale after hydrothermal treatment, the distributions of the formation potential of individual hydrocarbons of the composition C1—C5 by the activation energy scale (kinetic spectra) were determined. The kinetic spectra of n butane and n pentane do not change with increasing temperature of the hydrothermal experiment and increasing maturity of the organic matter. The maximum of the potential distribution on the activation energy scale of methane and ethane shifts to the region of higher values with increasing thermal maturity. The results can be used to clarify the conditions for the implementation of the gas formation potential in the domanik deposits of the Timan-Pechora basin.
The results of electron microscopic studies of the Lower Permian ooid dolomites (South Timan)
Authors: Vetoshkina O.
Published: December 2024

The article presents the results of studies of the Lower Permian dolomites containing ooids. They outcrop in the northeastern part of the East European Platform and are confined to the upper-middle reaches of the Vychegda River (South Timan, near the mouth of the Nem River). Electron microscopic studies have revealed the complex structure of the dolomites conditioned by their heterogeneous nature. We found ooids, remains of microphytophossils (microphytoliths), and biomorphoses from various faunal remains. The results of the conducted research can be interpreted in different ways. On the one hand, traces of bacterial communities were found in the structure of zooids (oolites) from the studied rocks, indicating their biochemogenic nature. In this case, the microbiota, by changing the environment, could contribute to the deposition of protodolomite phases in the course of its vital activity. On the other hand, the dolomites contain mineral phases testifying to the multiphase formation of rocks.
Genetic Associations of IL-2 (rs2069762) and EGR3 (rs3750192) Polymorphisms with Schizophrenia: A Meta-Analysis
Authors: Shibi Anilkumar Anu , Mariam Thomas Sheena , Veerabathiran Ramakrishnan
Published: December 2024

Abstract
Introduction: Schizophrenia (SCZ) is a severe mental illness influenced by genetic and environmental factors. Although genome-wide association studies (GWAS) have identified numerous genes linked to SCZ, their specific roles remain unclear. This meta-analysis explores the relationship between polymorphisms in the IL-2 (rs2069762) and EGR3 (rs3750192) genes and SCZ susceptibility.
Methods: A systematic review of nine studies was conducted using databases such as PubMed, Google Scholar, and ScienceDirect. The studies examined the IL-2 and EGR3 polymorphisms and their associations with SCZ risk across different populations. Fixed and random-effect models were used to analyze allele, dominant, recessive, and overdominant models. Subgroup analyses were conducted by ethnicity.
Results: For IL-2 (rs2069762), no significant associations with SCZ risk were found across all genetic models. The allele model (OR=0.94, p=0.34), dominant model (OR=0.85, p=0.55), recessive model (OR=0.93, p=0.76), and overdominant model (OR=0.94, p=0.76) all showed non-significant results. In contrast, EGR3 (rs3750192) demonstrated a significant association in the dominant model (OR=0.73, p=0.012) and the homozygous model (OR=0.70, p=0.004), suggesting a protective effect. Subgroup analysis revealed ethnic differences, with the Polish and Chinese groups showing significant protective effects for IL-2 and EGR3, respectively.
Conclusion: While IL-2 (rs2069762) shows no consistent association with SCZ, EGR3 (rs3750192) may confer a protective effect, particularly in certain ethnic groups. Further research is required to confirm these findings and understand the genetic mechanisms underlying SCZ risk across populations.
Addition of basil leaf (Ocimum basicilum L.) extract to AndroMed® extender improved the quality of spermatozoa of frozen thawed Simmental bull semen
Authors: Aditya Irawan  , Fajar Ramadhan Subiyantoro  , Suherni Susilowati  , Tri Wahyu Suprayogi  , Sri Pantja Madyawati  , Pudji Srianto  , Nove Hidajati  , Eduardus Bimo Aksono Herupradoto  , Kadek Rachmawati
Published: December 2024

This study aims to determine the best dose of basil leaf extract to add to AndroMed® semen extender to improve spermatozoa quality after freezing and thawing. This study used healthy, normal four-year-old Simmental bulls with good libido. The sample used was fresh semen from Simmental bull collected using an artificial vagina. This study used a completely randomized design (CRD) with three treatments and six replicates. Ejaculate that met the motility qualification of more than 70%, was divided into three groups, each extended in AndroMed® without the addition of basil leaf extract (T0), with the addition of 0.1% basil leaf extract (T1) and with the addition of 0.3% basil leaf extract (T2). Straw containing semen with 30 million spermatozoa/straw was processed using an IceCube automatic freezer (Minitube, Germany). The results showed that spermatozoa motility, viability, and spermatozoa plasma membrane integrity in the T2 group were higher (p <0.05) than those in the T0 and T1 groups, while spermatozoa morphological abnormalities in the T2 group were lower (p <0.05) than those in the T0 and T1 groups. There were no significant differences (p >0.05) in these parameters between groups T0 and T1. It could be concluded that the addition of 0.3% basil leaf extract to the AndroMed® extender could improve the quality of the semen of Simmental bulls after thawing.
Multiple arterial grafting: are women being left behind?
Authors: Qiu Yuan , Rubens Fraser D.
Published: December 2024

Multiple arterial grafting (MAG) has been evidenced to likely improve long-term mortality and morbidity outcomes compared with single arterial grafting during coronary artery bypass grafting (CABG), with current guidelines recommending its use. Notably, women make up less than 30% of the cohorts in the studies that inform these guidelines, and the use of MAG has not been well studied in the female population, despite the evidence that women present with more comorbidities and severe symptoms, and often perform worse after CABG compared with their male counterparts. Therefore, this comprehensive narrative review focuses on the currently available evidence examining MAG in women, and its use in on- and off-pump CABG.
Ferromagnetism of single atoms above room temperature
Authors: Cao Yitong , Geng Xun , Sathish CI , Li Mengyao , Ahmed Sohail , Qiao Liang , Yu Xiaojiang , Breese Mark B. H. , Zheng Rongkun , Chu Dewei , Yi Jiabao
Published: December 2024

The demands of the information era, driven by cloud computing and big data, necessitate high-density storage systems. In magnetic recording media, reducing bit size is crucial for significantly increasing areal density. Consequently, using single atoms as recording bits offers the potential to achieve unprecedented areal densities. However, achieving ferromagnetism in single atoms typically requires very low temperatures, and synthesizing large areas of single atoms for recording media remains a significant challenge. In this study, a straightforward mixing and stirring method was employed to intercalate a large number of Ni single-atoms into MoS2 nanosheets. Remarkably, room-temperature ferromagnetism was observed in all samples. Specifically, the 2% Ni-doped MoS2 exhibited a magnetic moment of 0.53 µ B, which is close to the theoretical value. The magnetization depends on the bonding between nickel and sulfur atoms. In 2% Ni-doped MoS2, nickel prefers to form Ni-S bonds, while at higher doping concentrations, S-Ni-S bonding is more prevalent, leading to antiferromagnetic coupling. The observed ferromagnetism in these higher-concentration-doped samples may be attributed to strain in the nanosheets induced by nickel intercalation or nanostructured NiS particles.
Мультимедійні бази даних у навчальних комплексах: виклики та можливості
Authors: Гордєєв Андрій Сергійович , Ткаченко Володимир Пилипович
Published: December 2024

Бази даних відіграють важливу роль у сучасних мультимедійних проєктах, забезпечуючи ефективне зберігання, управління та доступ до мультимедійних даних, зберігаючи при цьому їх надійність та цілісність. Такі проєкти дають можливість створення міждисциплінарних навчальних комплексів для інтеграції знань з різних галузей, формування цілісного бачення проблеми, а також розвитку критичного мислення та комунікативних навичок здобувачів вищої освіти. Використання мультимедійних баз даних у підготовці навчальних матеріалів збагачує навчальний процес можливістю застосування різноманітних форматів та методів, а також сприяє розвитку ключових компетентностей, необхідних для успішної адаптації у сучасному світі. Однак, крім переваг, використання баз даних у мультимедійних проєктах також пов’язане з низкою проблем: вони часто не зовсім структуровані, різні типи медіафайлів пред’являють різні вимоги до програмного забезпечення, системи управління базами даних вимагають різних алгоритмів стиснення інформації. Вирішення цих проблем потребує комплексного підходу, що включає вибір відповідної технології використання баз даних. Застосування SMART-компонентів у навчальному процесі відкриває нові перспективи розвитку освітнього процесу в напрямі технологій STEM.
Метою роботи є дослідження та аналіз впливу використання мультимедійних баз даних для підготовки навчальних комплексів. Зокрема, робота спрямована на поєднання різноманітних інструментальних модулів програмного середовища для вивчення окремих дисциплін, що сприяє більш глибокому та комплексному розумінню навчального матеріалу.
Для досягнення поставленої мети вирішено такі завдання: по-перше, інтегровано спроєктований мультимедійний застосунок до навчальної платформи Moodle; по-друге, передбачено під’єднання двох типів систем управління базами даних (Oracle SQL Developer — для контрольних завдань, які містять числові значення та передбачається їхня математична обробка; MongoDB — якщо контрольне завдання передбачає роботу з текстовою інформацією).
У роботі розглядаються актуальні проблеми розробки мультимедійного навчального застосунку на основі SQL і NoSQL баз даних, що мають високу продуктивність і масштабованість при колективному використанні. Вирішуються завдання інтеграції мультимедійного застосунку до навчальної платформи Moodle та підключення необхідних баз даних до навчального модуля. Запропоновано методику оцінки засвоєння знань з використанням рівня ентропії. Автори зазначають, що використання мультимедійних баз даних підвищує когнітивну активність учнів, збагачує навчальний процес та сприяє розвитку ключових компетентностей студентів, необхідних для успішної адаптації у суспільстві.
Оцінка якості гарячого тиснення фольгою на покривних матеріалах
Authors: Бараускєне Оксана Іванівна , Карандюк Любов Максимівна , Зигуля Світлана Миколаївна
Published: December 2024

Метою цієї роботи є дослідження процесу гарячого тиснення фольгою на покривних матеріалах з різними характеристиками. Провести пошук оптимальних режимів експериментальним шляхом, а також проаналізувати результати методом експертного оцінювання та дослідити покривну здатність матеріалів за допомогою програмного забезпечення. Досліджено вплив зміни температури робочої зони контакту фольги з різними зразками на якісні параметри при гарячому тисненні. Проаналізовано чіткість контурів зображення, покривну здатність.
Для дослідження обрано шість видів різного матеріалу з різною товщиною та фактурою, а саме вініл на паперовій основі марки Vigor 77401, Baladek 26303, Balakron 26402 та шкірзамінники Vivella 4727, Vivella 4716, Charme 4712. При проведенні експериментальних досліджень основну увагу приділено дослідженню впливу таких параметрів тиснення, які впливають на якість отримуваних відбитків, що є тиск, час тиснення і температура нагрівання штампа. Гаряче тиснення виконувалось при постійному тискові 3050 Н/см2 на двох різних тигельних пресах ручному та півавтоматичному. Значення температури коливались від 100 до 120° С, час контакту від 0,5 до 5 с.
За результатами проведених експериментальних досліджень та наведеними експертними оцінками побудовано графіки залежності якісних параметрів фольгованого відбитка від температури тиснення та часу контакту. Виявлено, що найкращий результат покривної здатності зразків гарячого тиснення фольгою досягнуто при оптимальному значенні температури на автоматичному пресі 110° С, а на ручному пресі — 120° С. При дослідженні впливу часу контакту на чіткість границь найвищої експертної оцінки отримало оптимальне значення температури на автоматичному пресі 110° С при часі контакту 1 с, а на ручному пресі — 120° С при часі контакту 4–5 с.
Дослідження точності кольоровідтворення відбитків флексографічного друку при застосуванні пантонних сумішевих фарб
Authors: Канєвський Богдан Миколайович , Зоренко Ярослав Володимирович
Published: December 2024

В статті досліджено якість відтворення відбитків флексографічного друку етикеткової продукції з використанням сумішевих фарб PANTONE. В основу дослідження входять такі процеси, як: замішування фарби; пробний друк на різних матеріалах та на різній лініатурі анілоксових валів; подальший аналіз якості кольоровідтворення відбитків.
В наведеній роботі застосовувалися наступні методи досліджень: аналітичний метод аналізу фахової літератури, спектрофотометричний аналіз, статистична обробка даних, регресійний та кореляційний аналіз, математичне моделювання.
В ході проведеного дослідження визначено закономірності впливу колірних властивостей задруковуваного матеріал, лініатури анілоксового валу та кількості складників у сумішевій фарбі PANTONE на точність кольоровідтворення відбитків в процесі виготовлення етикеткової продукції флексографічним друком. Застосування методики ручного пробного друку дозволило отримати задовільну якість відбитків на рівні ΔE ≤ 5 та ΔH ≤ 8 згідно вимог стандарту, особливо для відбитків, надрукованих на півглянцевому папері та на білій поліпропіленовій плівці.
Також, на основі експериментальних даних складено регресійне рівняння другого порядку для опису впливу технологічних режимів процесу флексографічного друку на якість кольоровідтворення.
Це дослідження відображає сучасний стан досліджень у межах флексографічного друку з використанням фарб палітри PANTONE. Результатом є систематизація рівнів процесу управління кольором сумішевої фарби, залежності рівня колірних спотворень та рівня спотворень колірного тону від значень лініатури растру анілоксового валу та задрукованого матеріалу при застосуванні фарб PANTONE, регресійне рівняння з поліномом другого порядку.
CULTURA DE PRECEDENTES NO SISTEMA JURÍDICO BRASILEIRO E AS MITIGAÇÕES DO SISTEMA CIVIL LAW
Authors: Ribeiro Vinicius Leonardo , De Toledo Rossi Alina , Mazzetto Cardozo Rafael
Published: December 2024

O presente artigo tem por objetivo analisar a estrutura do sistema jurídico brasileiro à luz dos sistemas Civil Law e a Common Law. O primeiro, utilizado na Europa continental e nos países por eles colonizados, baseia-se no ordenamento jurídico positivado, ao passo que o segundo, identificado na Grã-Bretanha e em suas colônias, toma como parâmetro as decisões proferidas pelos juízes e tribunais. Neste ínterim, será estudado em qual dos sistemas o ordenamento jurídico pátrio se encaixa, vez que, apesar de o Brasil utilizar a lei como matriz precípua, as decisões judiciais estão, cada vez mais, subordinadas às diversas súmulas e entendimentos judiciais diariamente proferidas pelas cortes e tribunais superiores.
MENTE, LINGUAGEM E INTERPRETAÇÃO LEGAL: INTENCIONALIDADE DERIVADA E INTERPRETAÇÃO LITERAL DE TEXTOS LEGAIS
Authors: Chaves Alysson Fernando Paiva , Campelo Olivia Brandao Melo
Published: December 2024

Este artigo explora a interpretação legal através da perspectiva dos estudos sócio-ontológicos de John Searle a partir da década de 60. A indagação central gira em torno da possibilidade de uma interpretação literal da lei. Utilizando os conceitos de atos de fala, intencionalidade, direção de ajuste e referência propostos por John Searle, o artigo analisa atos ilocucionários, direções de ajuste e a relação entre intencionalidade e interpretação jurídica. Conclui-se que o adágio latino "in claris cessat interpretio" pode ser entendido como um processo de esclarecimento de pressupostos elementares em contextos circunscritos. O termo "interpretação literal" sugere uma abordagem elementar contextualizadora do texto legal. Dessa forma, é impossível falar de um contexto interpretativo zero, ou uma interpretação literal que tome o texto da lei como auto-referente.
EGFR Level in Non-Small Cell Lung Cancers Is Associated with the Expression of SATB1 and EMT-Promoting Factors
Authors: Glatzel-Plucinska Natalia Malgorzata , Piotrowska Aleksandra , Olbromski Mateusz , Rzechonek Adam , Podhorska-Okolow Marzenna , Dziegiel Piotr
Published: December 2024

Epidermal Growth Factor Receptor (EGFR) expression is an important aspect in the non-small cell lung cancer (NSCLC) diagnosis and treatment. Therefore, it becomes important to identify factors that may influence EGFR level. There are reports suggesting that one of the positive EGFR gene transcription regulators may be Special AT-rich Binding Protein 1 (SATB1), but so far these observations have not been confirmed in NSCLC. Aim of the study: The main aim of the present study was to investigate the possible links between the EGFR and SATB1 expression on both protein and mRNA levels in NSCLC clinical samples and to correlate the obtained results with the clinical-pathological data of the patients. Additionally, we analyzed the relationships between the expression levels of EGFR and the known tumor promoters, including Ki67 prolif-erative antigen and EMT-promoting transcription factors (SLUG, SNAIL, and Twist1). Materials and methods: The study was conducted on 239 NSCLC clinical samples. The methods used included immunohistochemistry and chromogenic in situ hybridization (CISH). Results and conclusions: We demonstrated that EGFR expression in NSCLC was positively associated both with the SATB1 level and with the expression of EMT-promoting proteins. Moreover, we were the first to analyze EGFR expression exclusively in NSCLC cancer cells without the interference caused by respiratory epithelium and tumor stroma. Our analysis revealed that the prognostic significance of EGFR expression was dependent on tumor histology and differed significantly between the AC and LSCC samples.
Strengthening Earth-Fill Embankments with Waste Tyre Reinforcement for Improved Flood Resilience
Authors: Chowdhury Nuha , Stamataki Ioanna , Kloukinas Panos
Published: December 2024

The resilience of earth-filled embankments against flooding is experimentally investigated using a scaled laboratory model. The project aims to evaluate the effectiveness of low-cost strengthening methods and materials which can be easily implemented especially in developing countries. Investigating locally available materials like waste tyres and jute bags reveals promising options for strengthening embankments in these regions. The performance of waste tyres as reinforcement material connected using jute string was evaluated by conducting tests using four flow rates under two different scenarios: steady peak flow scenario with reinforcement and without reinforcement. Measurements of the embankment height along the cross-sectional width were recorded and the erosion level was analysed by quantifying sediment volume loss. Three successive modes of failure were determined: toe scouring, sliding, toppling. Direct correlation was observed between increasing discharge and water depth. Reinforcing the embankment significantly decreased erosion in the range of 30% - 50% under different flooding scenarios, therefore, highlighting its effectiveness in reducing failure risks and contributing to UN Sustainable Development Goals 9, 11 and 13.
Mindfulness-Based Training: A Novel Approach for Cultivating Sustainability Mindset in Business Leaders
Authors: Gonzales Carlos
Published: December 2024

This study examines the efficacy of mindfulness-based training programmes in cultivating sustainability mindsets among business leaders. Through qualitative analysis of 20 executive participants in a business school master's programme, the research investigates how mindfulness practices facilitate sustainable leadership development across three dimensions: knowing, being, and doing. The investigation employs longitudinal methodological approaches, incorporating pre-intervention document analysis and semi-structured interviews to examine participants' experiential learning. Findings reveal that mindfulness training catalyses sustainable mindset development through twelve distinct mechanisms, equally distributed across cognitive, existential, and practical domains. These mechanisms operate at personal, relational, and institutional levels, enhancing leaders' capacity to address complex sustainability challenges. Results demonstrate that mindfulness practices fundamentally transform leadership approaches by fostering enhanced interoceptive awareness, strengthened interpersonal dynamics, and expanded institutional consciousness. The study contributes to existing literature by establishing empirical links between mindfulness practices and sustainability mindset development, whilst providing practical insights for business schools seeking to integrate experiential learning approaches into leadership development programmes.
Performance Analysis of Scandium-Doped Aluminum Nitride-Based PMUTs Under High-Temperature Conditions
Authors: Lyu Haochen , Safari Ahmad
Published: December 2024

This paper investigates the performance of scandium-doped aluminum nitride (AlScN) piezoelectric micromachined ultrasonic transducers (PMUTs) under extreme high-temperature conditions. Key findings include significant warpage due to thermal expansion, increasing from 0.306 µm at room temperature to 1.823 µm at 150°C. Resonant frequency showed a linear drift, with frequency shifts reaching 44\% at 200°C. The impedance phase increased from -41.56° at room temperature to +2.45° at 200°C, and the electromechanical coupling coefficient rose to between 21.4\% and 68.6\% in the temperature range of 100°C to 140°C. High-temperature cycling also revealed irreversible frequency shifts, indicating lasting thermal effects on device integrity. These results provide crucial insights into the behavior of AlScN-based PMUTs in harsh environments, guiding their design and reliability evaluation for high-temperature applications.
Intensification of Heat Transfer in an Impinging Jet Using Turbulent Superstructures
Authors: Sharov Konstantin
Published: December 2024

An experimental study of the effect of spatially localized super-large-scale motion structures, propagating in a laminar gas impinging jet, on the dynamics and heat transfer was carried out. A hot-wire anemometer, a high-speed 2D PIV with a frequency of 7 kHz and gradient heat flux sensors were used as equipment. Air and carbon dioxide used as working gases. Puff-type superstructures with a longitudinal size of up to 20-30 nozzle diameters formed in a long pipe in a laminar-turbulent transition regime. These structures have a complex internal topology. Jet containing superstructures impinging on an obstacle leads to deforming of the flow near the surface and a decrease in heat transfer at the stagnation point. Data are obtained on local heat transfer in the region of the flow stagnation point at large distances to the obstacle (h/d = 20) in the Reynolds number range of 250-10000. It is shown that a laminar flow in a jet source corresponds to a more localized heat flux compared to the case of a turbulent regime in the source. The maximum heat transfer is achieved not for the Poiseuille profile in the channel, but in the case of a transitional regime with a small percentage of turbulent vortex structures
Biological Enhancement of Gingival Phenotype Using Injectable PRF – A Narrative Review
Authors: Pashova-Tasseva Zdravka , Mlachkova Antoaneta , Maynalovska Hristina
Published: December 2024

Modern dentistry is oriented to the specific needs of the patient both in terms of function and aesthetics. At the same time, the possibility to apply various minimally invasive and non-surgical procedures makes it possible to offer a treatment that is easily accepted by the patient, but also represents a therapeutic option with a low financial cost. Such an opportunity is offered by au-tologous blood products, whose potential in tissue regeneration and tissue improvement makes them the preferred means of choice both as a primary and as an additional treatment procedure in various areas of dentistry. Numerous studies have compared the potential of various blood products in periodontal therapy. The development of autologous blood products, such as in-jectable Platelet-Rich Fibrin (i-PRF), offers promising advancements in many areas of dental medicine. Injectable PRF stands out for its superior regenerative potential when compared to other autologous blood products like Platelet-Rich Plasma (PRP). Its application and exceptional qualities as a biomaterial, induce positive effects on osteoclast migration, proliferation and oste-ogenesis in general, enhanced antimicrobial activity, and improved outcomes in mucogingival surgery, sinus lift procedures, and, notably, in improving gingival phenotype. The present liter-ature review aims to summarize the possibilities of i-PRF in its application for the treatment and improvement of various clinical conditions including the gingival phenotype augmentation.pertinent keywords specific to the article yet reasonably common within the subject discipline.
Solving the Mystery of Origin of Life—GADV Hypothesis
Authors: Ikehara Kenji
Published: December 2024

The origin of life has been mainly studied based on three ideas, RNA world hypothesis, hydrothermal vent hypothesis and space-origin hypothesis. However, the “mystery” has not been solved still now in spite of strenuous efforts of many researchers for more than 40 years. On the contrary, I proposed one idea, [GADV]-protein world hypothesis (GADV hypothesis), about 20 years ago, which insists that life emerged from [GADV]-protein world formed by pseudo-replication of [GADV]-proteins. [GADV] or GADV means four amino acids, Gly [G], Ala [A], Asp [D] and Val [V]. It was found in subsequent studies that the first gene was formed through processes starting with immature [GADV]-proteins or in a bottom-up manner. Furthermore, it has been confirmed that the first genetic system composed of ds-(GNC)n RNA gene, anticodon stem-loop (AntiC-SL) tRNA (GNC primeval genetic code) and [GADV]-protein was established at the same time when the first gene was formed. It has been also confirmed that the genetic system never be established through a process starting with gene or tRNA. From the results, it has been concluded that life arose as expected by GADV hypothesis and that the “mystery” of the origin of life has been solved.
A Comparative Analysis of Rootstock, Seedling Age, and Anatomical and Physiological Studies for Watermelon Grafting
Authors: Huang He , Fu Du Gong , Li Wang Xian , Rong Wang , Li Chen Yan , Feng Zhan Yuan , Min Dang Xuan
Published: December 2024

Watermelon is an important fruit widely cultivated in tropical and temperate regions across the world. Particularly in China, both the production and consumption of watermelon lead the world. Watermelon is popular all over the world because it is rich in a variety of nutrients. Despite its widespread appeal, watermelon cultivation is frequently challenged by biological and abiotic stresses, which can significantly impair both yield and fruit quality. Grafting is a technique known to enhance the yield and quality of watermelons, yet the identification of suitable rootstocks and a comprehensive understanding of the cytological, physiological, and biochemical aspects of grafting remain elusive. In this study, we had identified the ‘Heiniu’ pumpkin variety as the optimal rootstock for watermelon grafting. Furthermore, we had determined that the most appropriate stages for scion and rootstock grafting are the one-true-leaf stage and the two-true-leaf stage, respectively. During the grafting process, the necrotic layer of the graft junction gradually dissipated, facilitating a tight connection between the scion and rootstock. Concurrently, there was a notable fluctuation in the levels of key plant hormones and protease activity throughout the healing process of the graft union, suggesting that these factors were pivotal to the success of watermelon grafting. Additionally, our findings indicated that grafting can significantly increase the sugar and titratable acid content within watermelons. This research contributes to a deeper comprehension of the histological and physiological mechanisms underlying watermelon grafting. It offers both theoretical insights and practical guidance essential for the advancement of watermelon grafting techniques.
Field Experiments on a Square Hole-Type Metamaterial: Exploring the Attenuation of Rayleigh and Love Waves
Authors: Zhang Xinchao , Liu Wei , Shi Qingfan
Published: December 2024

Seismic metamaterials (SMs) have gained significant attention for their ability to reduce seismic wave energy. However, the majority of research on SMs has been dominated by numerical simulations, with relatively few field experiments validating their effectiveness. Additionally, the focus has been primarily on attenuating Rayleigh waves, with less attention given to Love waves. In this study, We first designed a seismic metamaterial featuring a periodic and symmetric array of square holes using numerical simulations as our research platform. We then explored its attenuation effects on Rayleigh waves, particularly Love waves, through field experiments. The results revealed not only differences in energy attenuation between these wave types but, more importantly, uncovered a phenomenon we termed Bandgap-Induced Attenuation Mode Inversion within the ultra-broadband gap generated by SMs, where Love waves exhibited greater attenuation than Rayleigh waves below 50 Hz, while Rayleigh waves exhibited greater attenuation above 50 Hz. These findings highlight the necessity of considering both wave types when designing cost-effective seismic metamaterials, providing valuable insights for the development and application of metamaterials that can effectively mitigate the energy of different seismic wave modes.
How to Improve Employee Motivation and Productivity
Authors: Mustafakulova Sitora , Asrorova Amira , Ibragimov Khusen
Published: December 2024

Employee productivity is one of the vital factors that can influence not only organizational success and profitability but also overall employee satisfaction. This survey displays important elements to enhance workplace productivity focusing on leadership, work-life balance, motivation, salary, culture, affiliation, and reward. Additionally, flexible work arrangements and engagements are identified as significant factors of performance. The observation was explored in Uzbekistan, to analyze the productivity of workers and crucial drivers of efficiency. To gain data, surveys were shared with employees and analyzed in the Statistical Package for Social Sciences (SPSS) program. The result illustrates that the reward system, training opportunities, and democratic leadership significantly impact employee performance and satisfaction. Moreover, organizations should implement strategies that focus on perks, practice, and democratic leadership to improve the productivity of employees.
Estimation of Uncertain Parameters in Single and Double Diode Models of Photovoltaic Panels Using Frilled Lizard Optimization
Authors: Dal Süleyman , Sezgin Necmettin
Published: December 2024

Renewable energy sources are increasingly crucial for sustainable development. Photovoltaic (PV) systems, which convert solar energy into electricity, offer an environmentally friendly solution. Enhancing energy efficiency and minimizing environmental impacts in these systems heavily rely on parameter optimization. In this study, the Frilled Lizard Optimization (FLO) algorithm is proposed as a novel approach, integrating the newton-raphson method into the root mean square error (RMSE) objective function process to address nonlinear equations. Extensive analyses conducted on RTC France, STM6-40/36, and Photowatt PWP201 modules demonstrate the superior performance of the FLO algorithm. The RMSE values were calculated as SDM: 0.0030375 and DDM: 0.011538 for RTC France; 0.012036 for STM6-40/36; and 0.0097545 for Photowatt-PWP201, indicating significantly lower error margins compared to other optimization methods. Additionally, comprehensive evaluations were carried out using error metrics such as IAE, RE, and MAE, supported by detailed graphical representations of measured and predicted parameters. Current-voltage (I-V) and power-voltage (P-V) characteristic curves, as well as convergence behaviors, were systematically analyzed. This study introduces an innovative and robust solution for parameter optimization in PV systems, contributing to both theoretical and industrial applications.