bluuebunny/crossref_metadata_2025 huggingface dataset:
PELAKSANAA PEMBIAYAAN PENDIDIKAN DI SEKOLAH DASAR MAKASSAR
Authors: Andriani  , Mahani Mokhtar
Published: September 2023

Krisis keuangan yang melanda Indonesia pada 1996-1999 membawa dampak banyaknya siswa putus sekolah dasar. Kenaikan harga bahan bakar minyak pada 2004 ditakutkan membawa akibat yang sama. Untuk memberikan dukungan kepada keluarga miskin, mulai pada tahun 2005 pemerintah Indonesia membuat program dana Bantuan Operasional Sekolah (BOS) untuk sekolah dasar sampai sekolah menengah pertama. Kebijakan ini kemudian diikuti oleh program pendidikan gratis yang diprogramkan oleh berbagai pemerintah provinsi dan pemerintah kota/kabupaten. Penelitian ini menganalisis pelaksanaan pembiayaan pendidikan khususnya mengenai biaya operasional di sekolah dasar di Kota Makassar, Provinsi Sulawesi Selatan, Indonesia. Penelitian ini menggunakan pendekatan kualitatif dengan menggunakan desain studi kasus dan menerapkan analisis tematik. Penelitian dilakukan melalui pengumpulan data di lapangan dengan meminta tanggapan dari pejabat pemerintah di tingkat daerah, anggota DPRD, penggiat LSM dan responden di tingkat sekolah serta menafsirkan pelaksanaan/ penerapan pembiayaan pendidikan di sekolah dasar melalui wawancara, dokumen dan observasi. Temuan penelitian ini menemukan bahwa masih terdapat pungutan terhadap orang tua siswa, biaya operasional sekolah ternyata belum mencukupi untuk memenuhi semua keperluan pembelajaran di sekolah, serta indikasi kurangnya transparansi antara kepala sekolah dengan guru-guru serta orang tua siswa. Selanjutnya didapati bahwa sekolah yang menjadi sampel, ternyata kurang melibatkan komite sekolah dan tidak adanya pegawai administrasi di sekolah dasar. Oleh karena itu penelitian ini menyarankan masih perlu penambahan biaya operasional sekolah, perlunya transparansi dan perlunya perbaikan penggunaan dana di sekolah serta perlunya pengadaan pegawai administrasi di sekolah dasar.
STRATEGI GURU DALAM MENINGKATKAN HEALTHY LIFESTYLE MELALUI PROGRAM LITERASI HIDUP SEHAT
Authors: Edwita  , Hasanah Uswatun
Published: September 2023

Abstrak : Healthy lifestyle merupakan perilaku yang berkaitan dengan upaya atau kegiatan seseorang untuk mempertahankan dan meningkatkan kesehatannya. Perilaku ini sangat penting ditanamkan sejak usia sekolah dasar. Penelitian ini bertujuan untuk meningkatkan healthy lifestyle melalui program literasi hidup sehat. Metode penelitian ini berupa penelitian tindakan kelas, dengan prosedur perencanaan, pelaksanaan, observasi dan refleksi. Subjek pengembangan penelitian adalah siswa kelas I SDN Rawamangun 05, Jakarta Timur. Penelitian dilaksanakan dalam dua siklus dengan hasilnya siklus I ialah 71,35 % dan siklus II 95,88 %. Dapat disimpulkan bahwa program literasi hidup sehat dapat meningkatkan healthy lifestyle pada siswa kelas I SDN Rawamangun 05, Jakarta Timur.

 

Kata Kunci : healthy lifestyle, literasi hidup sehat
PEMANFAATAN MODEL PEMBELAJARA THINK PAIR SHARE DAN SNOWBALL THROWING PADA PEMBELAJARAN TEMATIK TERPADU BERBASIS LESSON STUDY DI SEKOLAH DASAR
Authors: Setiawan Heri , Aji Styo Mahendra Wasita , Aziz Abdul
Published: September 2023

Abstrak : Pembelajaran merupakan upaya untuk mencipatakan kondisi yang kondusif agar siswabelajar. Perubahan kurikulum yang ada di Indonesia memberikan paradigma baru perkembanganpembelajaran. Pembelajaran pada sekolah dasar sekarang menggunkan pola pengorganisasian isipembelajaran tematik terpadu pada semua jenjang kelas di seolah dasar. Guna memperkuatpelaksanaan pembelajaran dapat dimanfaatkan berbagai model pembelajaran diantaranya modelthink-pair-share dan snowball trhowing serta pendekatan lesson study.Tujuan dari artikel ini yaitumengkaji tentang pemanfaatan model pembelajaran think-pair-share dan snowball throwing padapembelajaran tematik terpadu di sekolah dasar dan pengembangan pembelajarannya dengan berbasispada lesson study. Model-model pembelajaran dan lesson study dapat dimanfaatkan untukmeningkatkan kualitas pembelajaran tematik terpadu di sekolah dasar.
PENGARUH KOMUNIKASI TERAPEUTIK PADA KUALITAS PENDIDIKAN SISWA BERKEBUTUHAN KHUSUS
Authors: Putri karisa
Published: September 2023

Pendidikan memiliki peran penting dalam menciptakan sumber daya manusia yang berkualitas. Tidak hanya mengerti secara teoritis, untuk menghadapi persaingan global yang semakin kompetitif dibutuhkan pula sumber daya manusia (SDM) yang dituntut untuk praktis dalam penggunaan teknologi dan keahlian khusus, termasuk bagi para penyandang disabilitas. Menurut data statistik yang dilansir oleh Biro Pusat Statistik bahwa terdapat kurang lebih 1.500.000 anak berkebutuhan khusus atau 0,7 persen dari total jumlah penduduk Indonesia. Data tersebut menunjukkan bahwa terdapat 317.016 anak berkebutuhan khusus yang berada dalam usia sekolah, sedangkan yang telah memperoleh layanan pendidikan kurang lebih 60.000 anak. Sebagai tenaga pengajar, guru memberikan pengaruh signifikan terhadap keberhasilan belajar siswa salah satunya penerapan komunikasi. Melalui metode penelitian kualititatif, artikel ini akan membuktikan penerapan komunikasi terapeutik pada siswa disabilitas dapat berpengaruh terhadap keberhasilan belajarnya.

Kata Kunci : Disabilitas, komunikasi terapeutik, dan keberhasilan belajar.
PENERAPAN LITERASI SAINS DALAM PEMBELAJARAN IPA UNTUK CALON GURU SD
Authors: Syofyan Harlinda , Trisia Lusiana Amir
Published: September 2023

Literacy is a complex process, which involves the formation of prior knowledge, culture, and experience to develop new knowledge and deeper understanding. Science literacy is the ability to understand science, communicate science, and apply the ability of science to solve problems. To improve the ability of scientific literacy in addition to requiring student motivation, teachers also need to consider learning strategies that are appropriate to the conditions and potential of students which in the learning process focuses on providing direct experience and the application of the nature of science. Science literacy exists to shape mindsets, behavior, and build human character to care and be responsible for himself, society, and the universe. Literacy learning in schools is carried out to achieve certain goals, but with the development of literacy times it is intended that students are able to achieve certain competencies, so as prospective school teachers who will face 21st century education, 21st century competencies that must be mastered are high-level understanding competencies, competencies critical thinking, collaborative and communicating competencies, and creative thinking competencies. The simulation method is used in the application of scientific literacy using the STL (Science Technology Literacy) method which consists of several stages, namely the contact, curriculum, elaboration, decision making, nexus, and evaluation stages. The results obtained are that the application of the simulation results obtained an average student assessment reached 82.3% with a total of students getting a very good grade of 60% and the rest good at 40%.
PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPE NUMBERED HEAD TOGETHER (NHT) UNTUK MENINGKATKAN HASIL BELAJAR TEMATIK
Authors: Maria Christina Sri Sunarsih
Published: September 2023

Abstrak : Tujuan  penelitian ini untuk mendeskripsikan pelaksanaan pembelajaran menggunakan model pembelajaran kooperatif  tipe NHT untuk meningkatkan hasil belajar pembelajaran tematik tema makanan sehat. Penelitian ini menggunakan rancangan penelitian tindakan kelas (PTK), yang dilakukan  dalam dua siklus yaitu siklus I dan Siklus II.Teknik  pengumpulan data yang digunakan yaitu observasi, dan tes. Data yang telah terkumpul dianalisis dengan  menggunakan teknik analisis deskriptif kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa pembelajaran dengan menerapkan model pembelajaran kooperatif tipe numbered head together berlangsung dengan baik yang ditunjukkan oleh nilai pelaksanaan pembelajaran pada siklus I mencapai 77,50 dan pada siklus II mendapatkan nilai 80,66. Penerapan model pemebelajaran kooperatiftipe Numbered Head Together (NHT) dapat meningkatkan hasil belajar tematik siswa. Ketuntasan klasikal pada siklus I memperoleh 77,50% dan siklus II sebesar 80,66%. Berdasarkan hasil penelitian denga metode kooperatif model NHT dapat berpengaruh positif terhadap peningkatan hasil belajar kelas V-b SDN Dukuh Menanggal I/424 Surabaya tahun pelajaran 2019-2020, serta model pembelajaran ini dapat digunakan sebagai salah satu alternatif pembelajaran tematik.

Kata Kunci : Pembelajaran Tematik, Kooperatif model Number Head Together.
PELAKSANAA PEMBELAJARAN PROBLEM BASED LEARNING PADA MATERI HIMPUNAN
Authors: Dian Kusmaharti
Published: September 2023

Abstrak : Penelitian ini bertujuan untuk mengetahui efektivitas keterlaksanaan pembelajaran berbasis masalah. Efektivitas pembelajaran berbasis masalah ini diterapkan pada materi himpunan yang berkaitan dengan hubungan dua himpunan dan operasi himpunan. Penelitian ini merupakan penelitian kualitatif dengan subjek penelitian adalah mahasiswa angkatan 2019-A Program Studi Pendidikan Guru Sekolah Dasar Universitas PGRI Adi Buana Surabaya  (PGSD-UNIPA Surabaya). Sumber data yang digunakan pada penelitian ini berasal dari mahasiswa yang mengikuti pelaksanaan perkuliahan dengan teknik pengumpulan data melalui teknik tes yang terdiri dari tes tulis dan non tes. Data non tes diperoleh peneliti melalui observasi, wawancara, angket, dan dokumentasi selama pelaksanaan pembelajaran berbasis masalah. Peneliti menggunakan triangulasi metode sebagai keabsahan dan analisis data yang diperoleh. Hasil penelitian ini menggambarkan pelaksanaan pembelajaran berbasis masalah dapat terlaksana dengan baik untuk materi himpunan pada mahasiswa PGSD-UNIPA Surabaya angkatan 2019-A. Hal ini terlihat dari ketercapaian target pembelajaran yaitu terlaksananya sintaks pembelajaran berbasis masalah memiliki kompetensi sikap yang baik selama pembelajaran berbasis masalah, serta ketepatan waktu dalam melaksanakan pembelajaran berbasis masalah sesuai dengan alokasi waktu pembelajaran yang telah ditentukan pada kontrak penelitian sebelum proses pembelajaran berbasis masalah ini dimulai. Selain itu, perolehan efektivitas ketercapaian aktivitas belajar mahasiswa memberikan dampak yang positif yaitu sebanyak 87,15% mahasiswa memiliki kompetensi sikap yang baik, 77,89% mahasiswa memiliki aktivitas belajar yang tinggi, dan mahasiswa memperoleh nilai di atas rata-rata sebanyak 83,32%.

Kata Kunci : pembelajaran berbasis masalah, himpunan, proses belajar, prestasi belajar
INTEGRASI KONSEP KEBENCANAAN DALAM IMPLEMENTASI KURIKULUM 2013 DI SEKOLAH DASAR
Authors: Almukarramah  , Fadhillah  , Ajat Sudrajat
Published: September 2023

Bencana adalah suatu peristiwa yang mengakibatkan dampak besar bagi populasi manusia,baik bencana alam, bencana non alam, dan bencana sosial. Permendikbud nomor 33 tahun 2019tentang Penyelenggaraan Program Satuan Pendidikan Aman Bencana untuk meyiapkan satuanpendidikan yang tanggap bencana. Melalui makalah ini akan kajian melalui integrasi konsepkebencanaan dalam implemementasi kurikulum 2013 di Sekolah Dasar dimulai dengan bagaimanaparadigma penanggulangan bencana di Indonesia, dalam konteks kurikulum Sekolah Dasar,pembelajaran tematik apa saja dari kurikulum 2013 yang dapat diintegrasikan kedalam konsepkebencanaan. Metode yang digunakan yaitu literature review dari perundang-undangan yangberkaitan dengan kebencanaan, hasil penelitian, modul, buku, buku panduan praktis. Selanjutnyadisadur melalui analisis konten yang berhubungan dengan kurikulum 2013 dan konsep bencana.Hasilnya menunjukkan bahwa terjadi perubahan paradigma penanggulangan bencana sebelum dansesudah terbit Undang-Undang Nomor 24 Tahun 2007 tentang Penanggulangan Bencana. Selanjutnyaditetapkan satu tema dari masing-masing kelas yang berkaitan dengan berpotensi dikembangkanuntuk materi kebencanaan berbasis kearifan lokal, diantaranya Kelas I, tema peristiwa alam. Kelas II,tema Keselamatan dirumah dan di perjalanan. Kelas III, tema Perubahan cuaca. Kelas IV, tema Peduliterhadap lingkungan hidup. Kelas V, tema Lingkungan sahabat kita. Kelas VI, tema Bumiku.
PENINGKATAN PEMAHAMAN SISWA TENTANG OPERASI HITUNG DAN BILANGAN DALAM PEMBELAJARAN MATEMATIKA MELALUI PENERAPAN METODE DISKUSI
Authors: Iin Sunarsih
Published: September 2023

This research is motivated by the low understanding of students regarding arithmetic and numerical operations. This study aims to improve students' understanding of arithmetic and numerical operations in mathematics learning of students in the class I Cibentar III State Elementary School using the discussion method. The research method used by researchers is a classroom action research, with a total of 17 students. This research took place in 2 cycles, each cycle consisting of 2 actions. The techniques used in data collection are observation, tests, interviews, documentation, and field notes. The results showed that the application of the discussion method could improve students' understanding of arithmetic and numerical operations in learning mathematics in class I Cibentar III Elementary School.
PENGEMBANGAN BAHAN AJAR BERBASIS AKTIVITAS MEDIA LILIN UNTUK MENINGKATKAN HASIL BELAJA IPA SISWA DI SEKOLAH DASAR
Authors: Rahmah Zahidah  , Nirwana Anas  , Nuranisa  , Nurmaulida Putri Sitorus  , Harahap Nurul Wardiyah , Buono Maratus Soleha Dian , Fiqih Triayu Wedari  , Nidaul Fitri Hamdani  , Bastian Pasaribu
Published: September 2023

Tujuan penelitian ini adalah untuk mengembangkan media pembelajaran perpindahan Kalor secara konduksi, konveksi dan radiasi. Dalam penelitian ini dikemukakan mengukur kelayakan media pembelajaran yang dikembangkan dari media online. Metode yang digunakan dalam penelitian ini, dengan melakukan metode Observasi langsung kepada siswa dan melakukan free test dan post test, kemudian melakukan dokumentasi sebagai bukti Hasil penelitian yang telah dilakukan. Bahan penelitian pengembangan materi perpindahan kalor ini, berupa alat peraga. Subjek penelitian ini adalah sisiwa kelas V Sekolah dasar, dan pembuktian keberhasilan penelitian ini adalah dengan pahamnya siswa-siswi sekolah dasar dengan materi yang dikembangkan. Tekhnik yang digunakan dalam penyampaian materi adalah tekhnik presentasi dan praktek secara langsung dengan siswa-siswi sekolah dasar.
Analisis Kemandirian Belajar Siswa terhadap Hasil Belajar Matematika Kelas XI IPA
Authors: Andri Andri , Rismawati Melinda , Tara Santa Aktavia
Published: September 2023

Penelitian ini bertujuan untuk menganalisis kemandirian belajar siswa terhadap hasil belajar matematika. Metode penelitian yang digunakan adalah metode deskriptif kualitatif. Subjek pada penelitian ini adalah siswa SMA Nusantara Indah Sintang dengan banyak subjek yang diteliti adalah sebanyak 3 orang siswa kelas XI IPA. Teknik pengumpulan data berupa wawancara dan dokumentasi mengenai kemandirian belajar siswa terhadap hasil belajar matematika. Kesimpulan diperoleh dari hasil analisis berdasarkan 7 indikator kemandirian belajar yang peneliti gunakan dari beberapa indikator para ahli. Berdasarkan analisis data dapat disimpulkan bahwa kemandirian belajar siswa dengan kategori hasil belajar matematika tinggi adalah sudah baik untuk belajar secara mandiri, sedangkan untuk yang kategori sedang sudah cukup untuk belajar secara mandiri dan kategori hasil belajar rendah adalah kurang mampu belajar secara mandiri.
Studi Literatur: Creative Problem Solving terhadap kemampuan berpikir kreatif dan pemecahan masalah matematis siswa
Authors: Laili Octadianti  , Hidajat Flavia Aurelia , Meiliasari Meiliasari , El Hakim Lukman
Published: September 2023

Penelitian ini dilatarbelakangi oleh kurangnya kemampuan berpikir kreatif dan pemecahan masalah siswa dalam pembelajaran matematika. Matematika adalah ilmu yang terstruktur dan sistematis, sebagai suatu kegiatan manusia melalui proses yang aktif, dinamis, dan generatif, serta sebagai ilmu yang mengembangkan sikap berpikir kritis, objektif, dan terbuka. Penelitian ini merupakan studi literatur dengan jenis penelitian kualitatif deskriptif dengan kajian kepustakaan yang berusaha menggambarkan Creative Problem Solving terhadap kemampuan berpikir kreatif dan pemecahan masalah matematis siswa. Tujuan dari penelitian ini adalah untuk mengkaji literatur tentang Creative Problem Solving terhadap kemampuan berpikir kreatif dan pemecahan masalah matematis siswa. Pengumpulan data dilakukan dengan mengumpulkan berbagai sumber tertulis, seperti artikel, jurnal, dan dokumen-dokumen yang relevan dengan kajian dalam penelitian ini untuk kemudian dibaca dan dikaji. Setelah data terkumpul, dilakukan pengujian dan pembandingan data yang ditemukan. Teknik analisis data dilakukan secara kualitatif dengan analisis isi dan pengutipan pendapat-pendapat yang sesuai. Hasil studi menunjukkan bahwa Creative Problem Solving merupakan salah satu model pembelajaran yang dapat mengembangkan aspek kemampuan berpikir kreatif dan pemecahan masalah. Model pembelajaran tersebut dirancang untuk variasi dari pembelajaran pemecahan masalah dengan teknik yang sistematis dalam mengorganisasikan gagasan kreatif untuk menyelesaikan suatu permasalahan. Berdasarkan hal tersebut, maka untuk mengembangkan kemampuan berpikir kreatif dan pemecahan masalah adalah dengan menerapkan model pembelajaran Creative Problem Solving yang memuat sebuah proses, metode, atau sistem untuk mendekati masalah dengan cara yang imajinatif dan menghasilkan tindakan yang efektif.
ANALISIS HUBUNGAN MINAT BELAJAR TERHADAP KEMAMPUAN PENALARAN MATEMATIS SISWA KELAS X
Authors: Dores Olenggius Jiran , Sopia Nurapni , Aming Aming
Published: September 2023

Penelitian ini bertujuan untuk  menganalisi  minat belajar terhadap kemampuan penalaran matematis siswa pada materi eksponen kelas X SMAN 4 Sintang. Dari hasil penelitian yang telah dilakukan oleh penulis, fakotr penyebab rendahnya penalaran matematis adalah kurangnya minat belajar siswa dalam belajar. Penelitian memiliki tujuan untuk menganalisi minat belajar dan kemampuan penalaran matematis. Metode yang peneliti gunakan dalam penelitian ini adalah deskriptif dengan pendekatan kualitatif. Objek  penelitian ini adalah siswa kelas X dengan jumlah peserta 15 orang. Adapun alat pengumpulan data yang digunakan dalam penelitian ini yaitu lembar observasi kegiatan siswa, lembar angket, dan lembar soal tes. Hasil penelitian pada siswa kelas X SMAN 4 Sintang berada pada kategori sangat rendah hal ini menunjukkan bahwa minat belajar siswa pada materi eksponen dengan rata-rata hasil  sebesar 10,82%. Sedangkan kemampuan penalaran matematis siswa sebesar 51,66% Faktor pendukung minat belajar siswa terhadap kemampuan penalaran matematis adalah motivasi, dorongan dari guru dan orang tua, pergaulan dan kedisiplinan, faktor penghambat yaitu pembelajaran yang belum menggunakan media pembelajaran, siswa sibuk sendiri. Upaya yang dilakukanguru guna mengatasi faktor penghambat minat belajar siswa terhadap kemampuan penalaran matematis siswa adalah guru memberikan motivasi kepada siswa, menyediakan media pembelajaran, memberikan dorongan kepada siswa untuk mempersipakan diri dalam pembelajaran yang akan berlangsung
Meningkatkan Kemampuan Komunikasi Matematis dan Self Confidence Siswa Melalui Model Pembelajaran Problem Based Learning
Authors: Lubis Risa Nursamsih , Rahayu Wardani
Published: September 2023

Salah satu kemampuan yang sangat penting untuk diperhatikan dalam pembelajaran matematika adalah kemampuan komunikasi matematis  selain itu terdapat aspek lain yang harus di perhatikan yaitu self confidence siswa. Penelitian ini bertujuan untuk memberikan gambaran sebagai kajian mengenai model Pembelajaran Problem Based Learning (PBL) dalam meningkatkan Kemampuan Komunikasi Matematis dan Self–confidence siswa. Metode yang digunakan adalah deskriptif, dengan mendeskripsikan hasil kajian Pustaka dari sekurang-kurangnya 30 artikel yang relevan. Hasil dari penelitian ini adalah Terdapat hubungan positif antara Self Confidence siswa dengan kemampuan komunikasi matematis dan Pendekatan Problem Based Learning efektif terhadap upaya meningkatkan kemampuan komunikasi matematis dan self confidence siswa.

Kata Kunci: kemampuan komunikasi matematis, self confidence, Model pembelajaran Problem Based Learning
Research on Mathematical Resilience: A Literature Review
Authors: Joe Azka Rabbihadi , Meiliasari Meiliasari , Rahayu Wardani
Published: September 2023

This systematic review has the objective to define the concept and to analyze the empirical studies of mathematical resilience through the following procedures: 1) developing a research question; 2) defining selection criteria; 3) developing the search strategy; 4) study selection process; 5) appraising the quality of studies; and 6) synthesis result. 19 articles were selected and reviewed in total. This study shown the concept representation and also insight of empirical studies about mathematical resilience.
Effect of Playing Position on Heart Rate and Blood Pressure in Brass and Wind Musicians
Authors: Luttrell Meredith J , Yaseen Manar , James Elizabeth , Kenney Vincent J , Wohlenhaus Bloomberg Jennifer
Published: September 2023

OBJECTIVE: The purpose of this study was to compare the impact of playing brass and wind instruments in seated versus standing positions on cardiovascular parameters in musicians. We hypothesized that heart rate (HR) and blood pressure (BP) would be higher while playing compared to
resting, and would be higher in standing compared to seated positions. METHODS: Ten musicians completed two study visits. In both, resting, supine HR and BP were recorded, followed by 30 minutes of playing. In one visit, participants played seated, and in the other, played while standing.
The order of these positions was randomized. BP and HR were recorded every 5 minutes during playing. RESULTS: Systolic BP was not affected by playing (p = 0.09, eta2 = 0.046) or position (p = 0.35, eta2 = 0.024). Diastolic BP increased while playing (p < 0.0001, eta2 = 0.32), but did not
differ between positions (p = 0.21, eta2 = 0.03). Mean arterial pressure (MAP) increased while playing (p < 0.0001, eta2 = 0.25), but did not differ between positions (p = 0.68, eta2 = 0.03). There was a significant time X position interaction for HR (p = 0.0001, eta2 = 0.037). Simple main
effects analysis revealed that HR was higher while playing in the standing compared to the seated position at all but one time point. CONCLUSION: Playing brass and wind instruments increases diastolic BP and MAP, regardless of playing position, while playing in the standing position induces
a higher HR compared to the seated position.
Musculoskeletal Pain and Injury in Indian Classical Dancers: A Systematic Review
Authors: Anand Prakash Akilesh , Subaskaran D , Akilesh Vinitha
Published: September 2023

The majority of current research on dance injuries has been on ballet, leaving a void in recent data on musculoskeletal injuries in Indian classical [IC] dance. The prevalence of injuries among IC dancers remains unclear, stressing the importance of injury epidemiology research for
improved diagnosis, treatment, prevention, and injury burden reduction. Through a thorough examination of published literature, this study sought to critically evaluate existing research on the epidemiology of musculoskeletal pain and injury in IC dancers. Using Google Scholar and PubMed,
a systematic evaluation of the online literature published in English was carried out from inception up to December 31, 2021 following PRISMA guidelines. For studies estimating injury prevalence, the Joanna Briggs Institute Prevalence Critical Appraisal Tool and the Risk of Bias Tool (RoBT)
were used to evaluate the studies’ quality. Of 3,917 studies identified, 6 studies, all cross-sectional, of low quality, with a high risk of bias, and featuring young Bharatanatyam and Kathak dancers, were determined to be admissible. Because of the studies’ heterogeneity, severe
study limitations, and methodological variability, a meta-analysis could not be carried out. The evidence from the current review is severely constrained, lacking generalizability to IC dancers as a whole and Bharatanatyam in particular. Since injury epidemiology is essential to the whole
injury-prevention puzzle, there is a need for standardization in future research, particularly with active and prospective injury surveillance, injury assessment, and injury reporting.
Non-invasive monitoring of midbrain dopaminergic progenitor cell production from human pluripotent stem cells
Authors: Iwasaki Mio , Drummond Nicola J. , McNay David E. , Canham Maurice A. , Tikhomirov Daniel , Arafa Donia , Lelos Mariah , Morizane Asuka , Kunath Tilo
Published: September 2023

Background

An emerging regenerative medicine for Parkinson's is cell replacement therapy with midbrain dopaminergic (mDA) progenitor cells produced from human embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs). Although protocols are well described, the process of hESC/iPSC differentiation remains challenging. Furthermore, different clonal iPSC lines can have variable responses to the same mDA protocol conducted in the same laboratory.

Methods

One solution to address this issue is to identify secreted biomarkers that are predictive of mDA differentiation efficiency. We used candidate approaches and unbiased proteomic methods to interrogate the secretome of cells as they are converting from pluripotent cells to committed mDA progenitor cells. We used conditioned media from two laboratories with different mDA protocols (Edinburgh, Kyoto) and multiple pluripotent stem cell lines (RC17, MasterShef7, 1231A3, 404C2).

Results

We have identified a collection of secreted molecules, including TFF3, CORIN, PDGFC, SERPINF1, and NRP1, that increase in conditioned media during the early stages of mDA differentiation. The kinetics of up-regulation and abundance of secreted biomarkers exhibited unique signatures for each cell line. However, in all cases we could identify biomarker signatures as early as day 4 of mDA protocols that were predictive of mDA differentiation efficiency. We further examined the secretome of differentiating striatal and cortical neurons to discover biomarkers of non-mDA cells, which led to the identification of PLAU and NCAM1 as diagnostic markers that should remain low during mDA differentiation. Finally, we multiplexed selected positive and negative markers to construct custom Luminex assay systems that can non-invasively analyse media samples during the time-course of mDA progenitor cell production for five hESC/iPSC lines.

Conclusion

We have identified a collection of over 10 secreted biomarkers useful for non-invasively monitoring the production of mDA progenitor cells for day 4 of differentiation from multiple clonal pluripotent stem cell lines.
Mental Health Literacy programmes prevent and support ongoing management of youth anxiety and depression: consultation and literature review
Authors: Botero-Rodríguez Felipe , Dhakal Sandesh , Pizarro Ana Beatriz , Koirala Rupesh , Khanal Astha , Peralta-Cuervo Andrés Felipe , Tandukar Dipesh , Khadgi Nalina , Bird Victoria , Lau Jennifer YF
Published: September 2023

Background
Enhancing young people's capacity to recognise, understand and manage emotional symptoms through mental health literacy (MHL) programmes may help attenuate the long-term burden of mental illness. This may be especially important in low-resource settings. We aimed to review the capacity of MHL programmes to prevent, support ongoing management, and reduce relapse of youth anxiety and depression. We explored both personal and contextual factors that could amplify their benefits, and through consultations with lived experience researchers, considered if and how these could be delivered in low-resource settings.
Methods
We systematically searched 6 databases for studies that evaluated the potential of MHL programmes to prevent, support ongoing management, and reduce relapse of youth anxiety and depression. We consulted young people and stakeholders on their perception of MHL programme delivery in low-resource countries/settings.
Results
We identified 17 relevant studies, covering a range of MHL programmes. Most MHL programmes targeted young people through educational settings. Teacher-delivered programs showed the clearest effects in improving recognition of anxiety/depression symptoms while programs supported by experts showed clearer effects on stigma reduction. Stakeholders highlighted the importance of MHL programmes and expressed possible barriers and solutions to implement them.
Conclusion
As young people are receptive to learning about mental health, it is critical to implement accessible MHL interventions early, especially in low-resource settings. Delivery by non-specialist practitioners in community settings could reflect one such strategy. Delivering these programmes may be a pre-requisite to understanding why and when individual resources are needed, bridging the gap in availability of mental health care.
Sex- and age-dependent susceptibility to ventricular arrhythmias in the rat heart ex vivo.
Authors: Okninska Marta , Duda Monika , Czarnowska Elżbieta , Bierla Joanna , Paterek Aleksandra , Maczewski Michal , Mackiewicz Urszula
Published: September 2023

Background
The incidence of life-threatening ventricular arrhythmias, the most common cause of sudden cardiac death (SCD), depends largely on the arrhythmic substrate that develops in the myocardium during the aging process. There is a huge deficit of comparative studies on the development of this substrate in both sexes, with a particular paucity of studies in females.
Methods
To identify the substrate of arrhythmia, fibrosis, cardiomyocyte hypertrophy, mitochondrial density, level of oxidative stress, antioxidant defense and intracellular Ca2+ signaling in isolated cardiomyocytes were measured in the hearts of 3- and 24-month-old female and male rats. Arrhythmia susceptibility was assessed in ex vivo perfused hearts after exposure to isoproterenol (ISO) and hydrogen peroxide (H2O2). The number of ventricular premature beats (PVBs), ventricular tachycardia (VT) and ventricular fibrillation (VF) episodes, as well as intrinsic heart rate, QRS and QT duration, were measured in ECG signals recorded from the surfaces of the beating hearts.
Results
After ISO administration, VT/VFs were formed only in the hearts of males, mainly older ones. In contrast, H2O2 led to VT/VF formation in the hearts of rats of both sexes but much more frequently in older males. We identified several components of the arrhythmia substrate that develop in the myocardium during the aging process, including high spontaneous ryanodine receptor activity in cardiomyocytes, fibrosis of varying severity in different layers of the myocardium (nonheterogenic fibrosis), and high levels of oxidative stress as measured by nitrated tyrosine levels. All of these elements appeared at a much higher intensity in male individuals during the aging process. On the other hand, in aging females, antioxidant defense at the level of H2O2 detoxification measured as glutathione peroxidase expression was weaker than in males of the same age.
Conclusion
We have shown that sex has a significant effect on the development of an arrhythmic substrate in aging. This substrate determines the incidence of life-threatening ventricular arrhythmias in the presence of additional stimuli with proarrhythmic potential, such as catecholamine stimulation or oxidative stress, which are constant elements in the pathomechanism of most cardiovascular diseases.
Propensity Score Matched Analysis for the Safety and Effectiveness of Remdesivir in COVID-19 Patients with Renal Impairment
Authors: Yang Eunmi , Choi Han Zo , Kim Subin , Oh Dong Hyun , Ahn Mi Young , Ham Sinyoung , Lee Eunyoung , Jeon Jaehyun , Kim Min-Kyung , Jang Hee-Chang , Park Sang-Won , Choi Jae-Phil
Published: September 2023

Backgrounds:
Remdesivir (RDV) is an antiviral agent approved for the treatment of coronavirus disease 2019 (COVID-19); however, is not recommended for patients with renal impairment. Due to limitations associated with prospective clinical trials, real-world data on the safety and efficacy of RDV in patients with renal impairment are necessary.
Methods
Propensity score-matched (PSM) retrospective analysis was conducted between March 2020 and September 2022 in COVID-19 patients with an eGFR < 30 mL/min in four Korean hospitals. The RDV treatment group was matched to the untreated control group. The safety and clinical outcomes in patients who received RDV were analyzed.
Results
A total of 564 patients were enrolled; 229 patients received RDV either for treatment or prophylaxis. On day 5, no differences in nephrotoxicity and hepatotoxicity were observed between the two groups. In multivariate analysis for new dialysis, RDV treatment was not a risk factor for new dialysis. Among the 564 patients, 417 were indicated for a 5-day course of RDV treatment and 211 patients were treated with RDV. After PSM, no differences in the clinical outcomes were observed between the two groups.
Conclusion
RDV use in COVID-19 patients with renal impairment did not result in significant nephrotoxicity or hepatotoxicity.
Criteria for Severe Dynamic Sagittal Imbalance in Adult Spinal Deformity and its Importance
Authors: Kim Yong-Chan , Ha Kee-Yong , Kim Sung-Min , Yoo Sunin , Li Xiongjie
Published: September 2023

Background
To analyze the characteristics of “severe” dynamic sagittal imbalance (DSI) in patients with adult spinal deformity (ASD) and establish criteria for them.
Methods
In total, 102 ASD patients with four cardinal signs of lumbar degenerative kyphosis were retrospectively analyzed. All patients underwent deformity corrective surgery and were divided into three groups according to the diagnostic criteria. The criteria were based on the Oswestry disability index scores and dynamic features (△Timewalk: time until C7 sagittal vertical axis [C7SVA] reaches ≥ 20 cm after the start of walking) of sagittal imbalance. The paravertebral back muscles were analyzed and compared using T2-weighted axial images. We performed a statistically time-dependent spinopelvic sagittal parameter analysis on full standing lateral lumbar radiographs. Lumbar flexibility was analyzed based on dynamic lateral lumbar radiographs
Results
Based on the diagnostic criteria, the 102 patients were classified into three groups: mild (△Timewalk ≥ 180 s, 35 patients), moderate (180 s > △Timewalk ≥ 30 s, 38 patients), and severe (△Timewalk < 30 s, 29 patients). There was a significantly higher signal intensity (533.4 ± 237.5, P < 0.05) and larger area of fat infiltration (35.2 ± 5.4, P < 0.05) in the back muscles of the severe group than in the mild (223.8 ± 67.6/22.9 ± 11.9) and moderate groups (294.4 ± 214.7/21.6 ± 10.6). The analysis of lumbar flexibility revealed significantly lower values in the severe group (5.8° ± 2.5°, P < 0.05) than in the mild and moderate groups (14.2° ± 12.4° and 11.4° ± 8.7°, respectively). The severe group had significantly lower lumbar lordosis (LL, 25.1° ± 22.7°, P < 0.05) and Pelvic incidence (PI)-LL mismatch (PI-LL, 81.5° ± 26.6°, P < 0.001) than the mild (8.2 ° ± 16.3°/58.7° ± 18.8°) and moderate (14.3° ± 28.6°/66.8° ± 13.4°) groups. In ROC curve analysis, PI-LL was statistically significant with AUC of 0.810 (95% confidence interval) when the baseline was set at 75.3°. The severe group showed more postoperative complications than the other groups.
Conclusions
We suggest the following criteria for severe DSI: C7SVA > 20 cm within 30 s after walking or standing, rigid lumbar curve < 10° on dynamic lateral radiographs, and PI-LL mismatch > 75.3°.
The importance of landscape during long-distance running activity
Authors: Gajdek Agata , Kasprzyk Idalia , Ortyl Bernadetta
Published: September 2023

Running outdoor has a positive impact on human health. Study attempted to address the issue of what are other aspects motivating to take up running. We were particularly interested in the landscape. Goal was also to determine the landscape values of the competition routes, which determine their popularity. We conducted surveys among the participants of the runs and spatial analyzes using GIS tools. Great landscape values of running routes can contribute to the activation of running society, especially women and city dwellers. The high diversity of the landscape of the cross-country routes, especially in terms of their relief and land use, significantly affects their high landscape rating. Route profile and running challenges are as important as landscape values. The landscape that runners observe during long-distance runs affects their regeneration and motivates them to finish the competition. People want to run in a visually beautiful mountain and foothill landscape. This study illuminates how the enchanting tapestry of landscapes not only fuels the passion for outdoor running but also underscores the intricate relationship between humans and their surroundings. The results enable us to establish the key principles for designing new running routes that support runners during their exertion.
Is adrenal venous sampling always necessary to differentiate between unilateral and bilateral primary aldosteronism? Lesson from the SPAIN-ALDO register
Authors: Ramírez Paola Parra , Marcos Patricia Martín Rojas , Fano Miguel Paja , Boillos Marga González , Peris Begoña Pla , Pascual-Corrales Eider , Cano Ana María García , Ruiz-Sanchez Jorge Gabriel , Delgado Almudena Vicente , Hoyos Emilia Gómez , Ferreira Rui , Sanz Iñigo García , Sala Mònica Recasens , Millan Rebeca Barahona San , César María José Picón , Guardiola Patricia Díaz , Perdomo Carolina María , Manjón-Miguélez Laura , Centeno Rogelio García , Percovich Juan Carlos , Román Ángel Rebollo , Gimeno Paola Gracia , Lázaro Cristina Robles , Ruiz Manuel Morales , Calatayud María , Collao Simone Andree Furio , Meneses Diego , Nuñez Miguel Antonio Sampedro , Quesada Verónica Escudero , Ribas Elena Mena , Sánchez Alicia Sanmartín , Diaz César Gonzalvo , Oliveira Cristina Lamas , Guerrero-Vázquez Raquel , Tous María Del Castillo , Gotarredona Joaquín Serrano , Alevras Theodora Michalopoulou , Mateo Eva María Moya , Hanzu Felicia Alexandra , Araujo-Castro Marta
Published: September 2023

Purpose: To evaluate whether the clinical, biochemical and radiological features of patients with primary aldosteronism (PA) can predict both main subtypes of PA.
Methods: A retrospective multicenter study of PA patients followed in 27 Spanish tertiary hospitals (SPAIN-ALDO Register). Only patients with confirmed unilateral or bilateral PA based on adrenal venous sampling (AVS) and/or postsurgical biochemical cure after adrenalectomy were included. Supervised regression techniques were used for model development.
Results: 328 patients [270 unilateral PA (UPA), 58 bilateral PA (BPA)] were included. The area under the curve (AUC) for aldosterone/potassium ratio and aldosterone responses following saline infusion test were 0.602 [95%CI 0.520 to 0.684] and 0.574 [95% CI 0.446-0.701], respectively, to differentiate UPA from BPA. The AUC was 0.825 [95% 0.764-0.886] when the prediction model with seven parameters – comorbidities (dyslipidemia, cerebrovascular disease, SAS), SBP, plasma aldosterone levels (PAC), hypokalemia and unilateral adrenal nodule >1 cm and normal contralateral adrenal gland on CT/MRI – was used. In patients without comorbidities, hypokalemia, SBP >160 mmHg, PAC >40 ng/dL, and unilateral adrenal lesions were associated with a likelihood of having a UPA of 98.5%. The chance of BPA was higher in individuals with comorbidities, SBP <140 mmHg, normokalemia, low PAC levels, and no adrenal tumors on the CT/MRI (91.5%).
Conclusion: A combination of high PAC, SBP >160 mmHg, low serum potassium, a unilateral adrenal nodule and no comorbidities could predict a UPA with a 98.5% accuracy.
Flood Risk Assessment Based on the Historical Disaster Statistics and the Index System Method: A Case Study of Hubei Province, China
Authors: Che Lusheng , Yin Shuyan , Guo Yishu
Published: September 2023

Flood risk assessment is a critical aspect of flood management. The historical disaster statistics method and the index system method are commonly employed for this purpose. In this study, we combine these approaches to assess the risk of flooding in Hubei province, China. Our methodology includes compiling flood disaster data from 1949 to 2000 to calculate the flood disaster extent and trend in each geographic unit, and flood hazard is assessed using these aspects. Additionally, we also select relevant indicators such as elevation difference, distance to water bodies, GDP, population, and percentage of construction land as flood vulnerability measures, and the weights for these indicators are determined using the Analytic Hierarchy Process (AHP). Subsequently, a risk assessment model is developed by integrating the hazard and vulnerability factors, and the flood risk assessment is conducted at a high-resolution grid scale of 1km × 1km. The results show that about 36.7% of the territory of Hubei Province falls into the medium-high risk category. It is observed that the risk level is higher in the eastern and southern regions, and lower in the western and northern regions. Notably, flood risk decreases radially outward from two high-value centers such as Wuhan and Yichang. Our assessment method demonstrates operational simplicity, high accuracy, and robustness. Moreover, the assessment results provide a high spatial resolution that can be further refined to the relative risks in different administrative hierarchical areas.
Health Economic Comparisonof Retrievable Self-expanding Full-covered Film Metal Stent and Endoscopic Dilation for Benign Anastomotic Stenosis after Esophagectomy of Esophageal Cancer: A Randomized Controlled Trial
Authors: Tao Zhang , Liu Jie , Pu Wenfeng , Ren Ninchuan , Feng Shenggang , Zhang Yan , Zhang Lisha , Li Feng , He Qingli , Lin Fengying , Du Zhonghan , Hu Xiaosan , Li Baohua , Zhang Guihua , Long Sizhe , Li Ying , Zhang Bing
Published: September 2023

Background: Endoscopic dilation (ED) is common and effective for improving strictures in patients with benign esophageal anastomotic stenosis (BEAS) after esophagectomy. A retrievable self-expanding metal stent has also been proven effective in treating strictures. However, evaluations comparing health economics of stent placement and ED for BEAS are lack.
Methods: In this prospective, randomized, controlled, multicenter study, BEAS patients between October 2020 and October 2021 at six centers were included. Patients were randomized into stent replacement (SR) or water balloon dilation (WBD) groups, and re-treatment interval times, body mass index (BMI) changes, dysphagia score, quality of life (QOL), treatment fees/times, total cost, daily cost, restenosis, and adverse effects assessed. Mann-Whitney U test was used for continuous variable analysis and Kaplan-Meier to calculate cumulative percentage and effective rate; significance was set at P<0.05.
Results: Re-treatment interventions were more frequent in the WBD group (3 vs. 1.2, p<0.05) and re-treatment interval times longer (60-days vs. 7-days, p<0.05). Patient compliance was lower in the WBD group (p<0.001), while treatment cost was higher in SR patients (5001 vs. 1812 yuan, p <0.001). Daily treatment cost was lower in SR patients (78.57 vs 86.29 yuan, p<0.05). QOL (97 vs. 86, p<0.05), changes in posttreatment BMI (0 vs -0.72, p<0.05), and posttreatment dysphagia score (1 vs. 2, p<0.05) were higher in SR patients. There were three adverse events, two stent migrations, and one patient died following ED.
Conclusions: SR patients had higher QOL due to longer retreatment intervals, fewer endoscopic interventions, and lower daily treatment costs.
Trial registration: The study was registered in the Chinese Clinical Trial Registry, number ChiCTR2000037864.
The carbon emissions calculation, decomposition and peak scenario simulation of meat, egg, and milk in China: from a production and consumption perspective
Authors: Zhou Kun , Chen Liu , Wu Jin , Li Hongyao , Wang Huan , Li Jianqiang
Published: September 2023

Characterizing and quantifying livestock carbon emissions helps mitigate temperature rise and potential climate risks. Here, the spatial and temporal characteristics of China’s carbon emissions of meat, egg, and milk are analyzed from the perspective of production and consumption. A driving factor decomposition model of carbon emissions of meat, egg, and milk production and consumption is established using the logarithmic mean Divisia index (LMDI). Using a static scenario analysis and dynamic Monte Carlo simulations (MCS), the evolution trajectory of carbon peak in meat, egg, and milk production and consumption in China during 2021–2030 is analyzed. China’s carbon emissions from meat, egg, and milk production and consumption have risen in 2020, reaching 794.1 and 465.88 Mt, respectively. Moreover, western China has the highest carbon emissions in production (33.84%). For consumption, the carbon emissions are mainly concentrated in the eastern region (42.96%). The key drivers of carbon emissions for this production and consumption are the farmland value and residential income effects, respectively. Conversely, reverse urbanization, agricultural industry structure, and food money purchasing power effects play significant suppressive roles. Under the business-as-usual scenario (BAU), China’s carbon emissions from meat, egg, and milk production and consumption in 2030 will increase by 40.1% and 4.86% from 2020, respectively. The middle low-carbon scenario (Mid-LC) mitigates carbon emission growth by 24.51% and − 5.7%, respectively, for the production and consumption of meat, egg, and milk in 2030 compared to 2020. In the highly low-carbon scenario (Hig-LC), production and consumption will achieve a carbon peak by 2030. Ultimately, this study highlights the importance of reducing carbon emissions from livestock on production and consumption, providing a new perspective for green development in China and other emerging economies.
Mutiple Hybrid Odontomas Involving All Four Quadrants of Jaws: A Rare Case Report
Authors: Arif Sana , Riaz Nabeela , Haq Ehsah-ul- , Nasir Hafiz
Published: September 2023

Odontomas are odontogenic tumors in which complete functional discrepancy of ameloblasts or odontoblasts occur with the development of enamel and dentine in an irregular arrangement due to lack of association of these cells to reach usual state of morphodifferentiation. Multiple hybrid odontomas present as many complex or compound odontomas involving one to all four quadrants of jaws. this present case is of a female aged 12 years who presented with mild pain and swelling in the right body of mandible for 1 year. After initial clinical and radiographic assessment, a tentative diagnosis of multiple hybrid odontomas involving all four quadrants of jaws was made. Surgical excision of the lesion which was causing facial deformity was performed. Excisional
biopsy report verified the clinical diagnosis. This case report describes the first unique case of multiple hybrid odontomas involving all four quadrants of jaws presented in last five years' literature.
Management of Cirrhotic: Double Edged Sword
Authors: Khan Jibran Umar Ayub , Shah Azhar Zahir , Qaisar Ayesha
Published: September 2023

Cirrhosis of liver has been the centre of attention for all the gastroenterologists for decades in terms of different manifestations and complications and at the same time very challenging to manage.1 There has been some success but not complete eradication of the
disease as the risk factors including chronic hepatitis B, C, autoimmune hepatitis , Wilson disease, and most importantly alcohol especially in the western countries remain a daunting task to treat.2 Those who are compliant to treatment are relatively easy to address. Without treatment the complications are devastating leading to the death of the patient.