bluuebunny/crossref_metadata_2025 huggingface dataset:
Reaching Forest Workers with Yellow Fever Vaccine Through Engagement of the Private Sector in Central African Republic
Authors: Noufack Gertrude , Bissengue Placide , Zobanga Junior Koma , Malingao Junior Stève Cyrille , Keita Mory , Razaiarimanga Marie Constance , Raguenaud Marie-Eve
Published: December 2024

Background/Objectives: Yellow fever (YF) outbreaks continue to affect populations that are not reached by routine immunization services, such as workers at a high risk of occupational exposure to YF. In the Central African Republic (CAR), YF cases were detected in districts characterized by the presence of workers in forest areas. We developed an innovative approach based on a local partnership with private companies of the extractive industry to administer YF vaccine to workers in remote areas during the response to an outbreak. Methods: The planning stage of the campaign included the mapping of forestry and mining companies through the involvement of national and/or local representatives of companies from both the formal and informal sectors. Information sessions and mobilization targeted the heads of operating companies. Advanced and mobile strategies were used to target workers on their work site. Companies provided logistical support including transportation and communication and set up temporary vaccination posts. Results: Using this local partnership, it was possible to vaccinate over 70,000 workers (5.8% of the entire vaccinated population) in hard-to-reach areas, protecting them from YF. This represented around 47% of the estimated number of workers and dependents. The partnership with the private sector also contributed to increasing knowledge on the risk of YF and means of protection among a high-risk community. Conclusions: Private companies represent potentially useful actors that can contribute to the protection of high-risk workers and to the prevention and control YF outbreaks. The experience in the CAR has demonstrated that it is possible to obtain support from private companies, including informal ones, for a vaccination campaign.
Residues of Tetracycline, Erythromycin, and Sulfonamides in Beef, Eggs, and Honey from Grocery Stores in Knoxville, Tennessee, USA: Failure of Cooking to Decrease Drug Concentrations
Authors: Sarkar Shamim , Kania Stephen A. , Abouelkhair Mohamed A. , Whitlock Brian , Okafor Chika C.
Published: December 2024

This study evaluated the concentrations of tetracycline, erythromycin, and sulfonamide in beef, eggs, and honey products sold at grocery stores and whether standard cooking to 160 °F (71 °C) reduced the concentrations of antimicrobials spiked into the evaluated food products. In June 2021, the concentrations of selected antimicrobials in 65 samples (8 beef, 48 eggs, 9 honey samples) purchased from grocery stores within Knoxville, Tennessee, were measured using enzyme-linked immunosorbent assays. The Kruskal–Wallis test was used to assess the differences in the median tetracycline concentrations across food types, while the Mann–Whitney test was used to compare the erythromycin residue concentrations between beef and honey. Linear regression was used to analyze whether standard cooking at 160 °F (71 °C) reduced antimicrobial concentrations. Detectable tetracycline concentrations were found in all beef (8/8, 100%), eggs (46/48, 96%), and honey (9/9, 100%) samples, with median concentrations of 7.73, 5.62, and 13.13 µg/kg, respectively. Honey had significantly higher tetracycline concentrations than eggs (p = 0.002). Detectable erythromycin concentrations were found in beef (5/8, 63%) and honey (9/9, 100%), with median concentrations of 0.14 µg/kg for beef and 0.48 µg/kg for honey. None of the antimicrobial concentrations found in the beef and egg products exceeded the U.S. FDA’s maximum residue limits (MRL). Sulfonamide concentrations were undetectable in the beef and egg products. The concentrations of tetracycline, erythromycin, and sulfonamide spiked into the food products did not change significantly in response to cooking to 160 °F (71 °C). The antimicrobial concentrations found in the selected commercial food products were below the MRL, and cooking appeared to not reduce the spiked antimicrobial concentrations in the evaluated food products.
The Role of Family Functioning in Over-Adaptation and Subjective Well-Being Among Japan’s Youth: The Moderating Effect of Gender Differences and Rumination
Authors: Zhang Mengting , Utsunomiya Hiroshi
Published: December 2024

This study investigates the influence of family functioning on the subjective well-being of Japanese university students, focusing on the serial mediation roles of internal and external aspects of over-adaptation and the moderating effects of gender and rumination. Utilizing a cross-sectional survey of 219 university students, this study gathered data on a variety of factors including family functioning, over-adaptation, subjective well-being, and demographic variables. Key findings indicate that effective family functioning reduces the detrimental impacts of over-adaptation on internal aspects, thereby enhancing students’ subjective well-being. This study substantiates the application of family system theory in developmental psychology, providing empirical support for interventions aimed at improving students’ psychological health. Moreover, it highlights the role of rumination as a significant moderator in the relationship between over-adaptation and subjective well-being, suggesting avenues for further investigation into individual psychological coping mechanisms. This research has profound implications for the development of targeted family interventions and mental health strategies within clinical psychology.
Livros de literatura infantil do 1º ao 3º ano do ensino fundamental: escolhas docentes
Authors:   , Nascimento Camila Tassi
Published: December 2024

Compreendendo que a literatura infantil exerce importante papel na formação humana, uma vez que é capaz de contribuir para a construção de sujeitos críticos e reflexivos, e que os livros de literatura infantil fazem parte do cotidiano escolar, a presente pesquisa buscou conhecer que critérios docentes usam para a escolha de livros de literatura infantil do 1º ao 3º ano do Ensino Fundamental. A fim de impulsionar as entrevistas com as docentes, acerca dos livros de literatura infantil e do que estabelecem como critérios para escolhê-los, selecionamos, dentre os livros do PNLD Literário 2018, aqueles que apresentaram maior incidência de escolha pelas escolas da rede municipal na qual as docentes trabalham. Para que pudéssemos identificar nas falas das docentes os critérios que nortearam a escolha dos títulos de literatura infantil e verificar a participação na escolha dos livros do PNLD Literário, adotamos como metodologia de pesquisa a Análise de Conteúdo de acordo com as orientações de Bardin (2016). Assim, foi possível constatar que predomina, dentre os critérios, a escolha de livros de literatura infantil enquanto recurso didático a ser usado em sala de aula, especialmente para o ensino de leitura e escrita.
Letra & imagem, gênero & paisagem: mulheres sertanejas entre história, literatura e fotografia
Authors:   , Oliveira Daniela Barbosa de
Published: December 2024

Esta pesquisa parte da constatação da aparente nulidade representativa do conjunto do que convencionamos chamar de "mulheres sertanejas" no clássico Os Sertões (1902), de Euclides da Cunha. Dividida em três eixos norteadores (terra, homem e luta) e em consonância com o projeto de nação posto em prática ao longo de todo o século XIX, a obra pouco se debruça sobre a participação daquelas que comprovadamente compuseram a maior parte do séquito de Antônio Conselheiro, bem como do Arraial de Belo Monte. Tendo em vista o caráter paradigmático da narrativa euclidiana a respeito do conflito de Canudos, as produções posteriores que também se arriscaram a contá-lo, invariavelmente tiveram em Os Sertões (1902) uma indispensável referência informativa e simbólica sobre o desenrolar dos eventos de 1896-97, que culminariam naquele que é, ainda hoje, considerado o maior massacre da história nacional. Deste modo, entendendo que as releituras contemporâneas a respeito de Canudos tiveram de lidar com a ausência narrativa sobre a diversidade de gênero naquele contexto, foi nosso objetivo observar como duas destas obras, o romance A Guerra do Fim do Mundo (1981), de Mario Vargas Llosa, e as fotografias de Maureen Bisilliat editadas em Sertões: Luz e Trevas (1982) se relacionaram com este padrão narrativo ensejado por Euclides: Perpetuando-o? Superando-o? Reelaborando-o conforme as demandas de seu tempo? Aspectos como a trajetória e a produção precedente dos autores, um peruano e uma inglesa naturalizada brasileira, bem como as implicações do uso do suporte fotográfico em sua relação com a literatura, também serão considerados como importantes elementos de compreensão deste recorte temático.
Censura negociada: as telenovelas de Dias Gomes na Rede Globo entre 1969 e 1979
Authors:   , Garcia Emilla Grizende
Published: December 2024

A presente tese tem como objetivo central analisar, a partir dos processos censórios, as telenovelas de autoria de Dias Gomes veiculadas no horário das 22 horas, na Rede Globo de TV, como resultado de uma complexa negociação estabelecida entre a emissora e seus interesses de mercado, o autor e a Censura de Diversões Públicas, no intervalo dos anos de 1969 a 1979. Desde modo, será problematizada a combinação antagônica de um autor notadamente de esquerda, como Dias Gomes, contratado por uma emissora liberal como a Rede Globo - que apoiava o Estado autoritário – que produziu e veiculou obras com certa dimensão sociopolítica, as quais foram rigorosamente monitoradas e mutiladas pela censura federal. As telenovelas do autor extrapolaram os espaços usualmente destinados aos programas desse formato e foram alocadas pela Censura de Diversões Públicas a uma zona delimitada, o horário das 22 horas. Dessa forma, esta pesquisa buscou evidenciar dados e análises que viabilizam a hipótese de que as telenovelas de autoria de Dias Gomes, exibidas e/ou produzidas para o horário das 22 horas, podem ser avaliadas como o resultado de um complexo processo de negociação entre o autor, a Rede Globo de TV e a Censura de Diversões Públicas. Almejamos com este trabalho contribuir para uma análise que problematize os laços de sociabilidade, as articulações de poder no meio televisivo e a ação da Censura Federal, compreendendo as tensões e as determinações multilaterais entre as formas culturais e as forças históricas.
EXPERIENCE AND PROSPECTS FOR THE DEVELOPMENT OF CONSTITUTIONAL CONTROL: DOMESTIC AND FOREIGN PRACTICE
Authors: Nesmeyanova Svetlana E.
Published: December 2024

The author analyzes the history and present of constitutional control in Russia. The issues
of improving the legal regulation of the organization and activities of the Constitutional Court
of the Russian Federation are considered, taking into account their own national experience
and practice of constitutional justice bodies in foreign countries. It is shown how the powers
of the constitutional justice body are changing, the list of acts subject to verification by the
Constitutional Court of the Russian Federation is expanding, and the range of subjects entitled
to appeal to this Court is being clarified. A different approach was also analyzed in relation
to the constitutional control bodies of the subjects of the Russian Federation. The author
notes that having stated in 1996 the right of the subjects to create their own constitutional
(statutory) courts, the federal legislator in 2020 obliged the subjects to abolish these bodies.
At the same time, creating constitutional (statutory) councils under regional parliaments was
allowed. Only three republics within the Russian Federation have established constitutional
councils. A number of subjects have adopted laws or are only discussing the need for such
bodies. The author concludes that the attitude of the subjects to this possibility is negative.
O impacto da tirzepatida no Diabetes Mellitus: uma revisão de literatura
Authors: Abreu Louise Theresa de Araújo , Salvador Fernanda , Nunes Maria Luiza , Moura Ana Carolina de , Carvalho Rodrigo Mendes
Published: December 2024

O Diabetes Mellitus tipo 2 (DM2) é uma doença crônica que afeta milhões de pessoas em todo o mundo. Nos últimos anos, surgiram novas classes de medicamentos que prometem melhorar o manejo do DM2, entre eles a tirzepatida, um agonista dual dos receptores de peptídeo semelhante ao glucagon tipo 1 (GLP-1) e polipeptídeo inibitório gástrico (GIP), ainda não comercializada no Brasil. Esse fármaco se destaca ao combinar a redução efetiva da hemoglobina glicada (HbA1c) à uma perda ponderal importante, características fundamentais no tratamento do diabetes e na prevenção de suas complicações, como as cardiovasculares.
Os efeitos da lenalidomida no tratamento da síndrome POEMS
Authors: Tranhago Meyli Passarela , Costa Bernardo Donato , Cunha Lucas Soares , Bello Yanes Brum
Published: December 2024

A síndrome POEMS é uma doença paraneoplásica rara, caracterizada por neuropatia periférica, organomegalia, endocrinopatia, distúrbio de células monoclonais plasmáticas e alterações cutâneas. Sua patogênese permanece desconhecida, contudo, estudos relacionam o aumento de citocinas, como fator de crescimento endotelial vascular (VEGF), e a discrasia de células sanguíneas como achados importantes na atividade da doença. No tratamento utiliza-se a talidomida, porém, a refratariedade da doença em alguns pacientes sob esta terapia motivou pesquisas em relação ao uso alternativo de lenalidomida com dexametasona.
Visitas domiciliares no aprimoramento do gerenciamento do Diabetes Mellitus
Authors: Ferreira João Mário Alves , Silva Tayane Souza , Sousa Maria Fernanda Jacobino de , Matos Mattheus Leandro Costa de , Alves Eliel Silva
Published: December 2024

O Diabetes Mellitus é uma doença crônica de elevada prevalência e alto risco, visto que está relacionado a graves acometimentos, complicações dispendiosas e diminuição da qualidade de vida. Assim, medidas devem ser apontadas para auxiliar no gerenciamento eficaz dessa doença, incluindo os pontos primordiais desse cuidado - suporte socioambiental, tratamento médico e autogestão -, sendo o acompanhamento médico através de visitas domiciliares uma estratégia de destaque para alcance dessa finalidade.
Uso de esteroides anabolizantes e efeitos cardiovasculares: saúde ou estética?
Authors: Teixeira João Victor Marques , Piedade Marina Cleto Miarelli , Cavalcanti Paulo Sérgio de Oliveira
Published: December 2024

O uso de esteroides anabolizantes, formas sintéticas de testosterona, tem se tornado cada vez mais popular entre os praticantes de esportes, primordialmente não competitivos, como uma alternativa rápida de obtenção de resultados estéticos (hipertrofia muscular). Sendo assim, é necessário reconhecer possíveis efeitos deletérios dessas substâncias no aparelho cardiovascular, visto que já se demonstrou em algumas séries, relação com arritmias e morte súbita.
العمليات بعملات أجنبية وترجمة القوائم المالية الأجنبية: دراسة مسحية للممارسات المحاسبية في بعض الشركات السعودية
Authors: سجيني طلال إبراهيم
Published: December 2024

يهدف هذا البحث إلى دراسة الطرق والمداخل المستخدمة في القياس والمعالجة المحاسبية الترجمة العمليات والقوائم المالية الأجنبية وتقييمها في ضوء هدف توفير المعلومات المحاسبية المتعلقة بالعمليات والقوائم المالية الأجنبية الملائمة لتقييم أداء الشركات الأجنبية التابعة. كما يهدف البحث إلى استقراء واقع الممارسات المحاسبية الفعلية لمشكلة أسعار الصرف وكيفية معالجتها في بعض الشركات السعودية من خلال دراسة مسحية للقوائم المالية التي تعدها تلك الشركات. وقد أوضحت الدراسة المسحية أن الممارسات المحاسبية الفعلية في بعض الشركات الصناعية السعودية المساهمة في مجال قياس العمليات والقوائم المالية الأجنبية وترجمتها، تتفق كثيراً مع بعض توصيات فقرات معيار المحاسبة الدولية رقم (۲۱)، وأن آثار التضخم لا تؤخذ بعين الاعتبار عند ترجمة القوائم المالية الأجنبية في هذه الممارسات المحاسبية السعودية.
تكلفة المعلومات التامة لتقدير معلمة الموضع للتوزيع الأسي
Authors: حمدي حسني إبراهيم
Published: December 2024

تستعرض هذه الدراسة دور تكلفة المعلومات التامة لتقدير معلمة الموضع للتوزيع الأسي. لقد تم دمج طرق التقدير بالنقطة وطرق التقدير باستخدام فترات ثقة في طريقة واحدة باستخدام تكلفة المعلومات التامة للاستفادة من المعلومات المتاحة بطريقة مثلى، وبالتحديد فقد تم مراجعة طريقة التقدير بالنقطة من خلال إطار أشمل وأوسع وهو إطار فترات الثقة حيث أن المعلومات اللازمة لإجراء التقدير بالنقطة هي معلومات غير معروفة مسبقاً. ولقد تم تقديم هذه الطريقة من خلال التجربة الثلاثية. أيضاً تم التعرف على بعض المؤشرات المتعلقة بحساسية التجربة الثلاثية في التعرف على التغيرات التي قد تطرأ على معلمة التوزيع الأسي.
نموذج لإمكانية الخصخصة ومدى فاعليتها في الدول النامية
Authors: قوته محمد محمد , العالم أحمد وضاح , كراسيك ميرك
Published: December 2024

يعتبر موضوع البحث "تحويل المشروعات العامة إلى مشروعات خاصة" من الموضوعات الهامة لتقييم جميع الاعتبارات لعملية الخصخصة والتي تحتل مكاناً بارزاً في الفكر الإداري والاقتصادي لوضع السياسات السليمة للقيام بهذا التحويل. وهدف هذا البحث وضع نموذج رياضي لإمكانية الخصخصة ومدى فاعليتها، وتم معالجة الموضوع على أربع مراحل: أولاً، مناقشة الجوانب والنظريات المتعددة للخصخصة من حيث أهدافها وأغراضها ومدى نجاحها. ثانياً، النظر إلى العوامل المؤثرة على المشروعات الخاصة وتلك العوامل التي تؤثر على المشروعات العامة. ثالثاً، القيام بوضع نموذج خاص بالعناصر الأساسية لعملية الخصخصة (من حيث الكفاءة، التقنية، الإنتاج، الأرباح،...). وأخيراً تم تطبيق النموذج على إمكانية الخصخصة في المملكة العربية السعودية بغية الخروج بتوصيات ومقترحات هادفة.
حساسية المدير للعدالة وعلاقتها بترتيب الأهمية النسبية للعوائد الوظيفية: دراسة ميدانية مطبقة على عينة من المديرين الكويتيين
Authors: حموده عبدالناصر محمد
Published: December 2024

مازالت نظرية Adams للعدالة عرضة للنقد لافتراضها أن الأفراد يسلكون نمطا واحدا في ردود أفعالهم نحو إدراك عدم العدالة، مهملة بذلك ما بينهم من فروق نفسية. ويمثل هيكل Huseman الخاص بحساسية الفرد للعدالة محاولة جادة لتطوير النظرية للتغلب على مشكلة الفروق النفسية. الدراسة الحالية محاولة تكميلية في هذا المجال، حيث اختيرت عينة عشوائية بسيطة من المديرين الكويتيين قدرها 246 مفردة لقياس مدى حساسيتهم للعدالة، وأثر هذه الحساسية في ترتيبهم لأهمية 20 عائدا وظيفيا مصنفة في 5 فئات. علاوة على دعم نتائج الدراسة للهيكل التنظيري المقترح وعلاقته بإدراك الأفراد لأهمية العوائد، تقدم الدراسة مجموعة من التوجيهات البحثية المستقبلية لتطوير الاستفادة منه على المستويين البحثي والتطبيقي.
قياس القيمة المعرضة للخطر في محافظ الأوراق المالية
Authors: موسى عماد أحمد , اللوغاني نبيل عيسى
Published: December 2024

يتعلق هذا البحث بمفهوم "القيمة المعرضة للخطر"، وهو أسلوب جديد نسبياً لإدارة المخاطر، حيث يتناول وصف هذا المفهوم ويبين أهميته التطبيقية. ويتناول أيضاً، بالشرح ثلاثة مداخل لقياس "القيمة المعرضة للخطر" هي: المدخل المعلمي، والمدخل التاريخي، ومدخل المحاكاة. وقد تم استخدام المدخلين المعلمي والتاريخي لحساب "القيمة المعرضة للخطر" لمحافظ مكونة من أسهم مدرجة في سوق الكويت للأوراق المالية. وجاءت النتائج شديدة الحساسية للافتراضات ذات الصلة. وحيث أن هذه النتائج قد كشفت عن أن عوائد الأسهم لا تنتمي إلى التوزيع الطبيعي، فإن إعطاء مصداقية أكبر "للقيم المعرضة للخطر" التي تم إيجادها باستخدام المدخل التاريخي هو المرجح.
نموذج رياضي لإدارة ناقلات النفط باستخدام أساليب النقل والجدولة
Authors: حسن ميرزا حسين , اليعقوب سالم محمد
Published: December 2024

يتناول موضوع البحث استخدام النماذج الرياضية لإدارة ناقلات النفط وجدولة الناقلات لنقل النفط ومواده المشتقة من الدول المصدرة إلى العملاء. ولتلبية الطلب على مواد النفط الخام ومشتقاته تلجأ الدول المصدرة إلى استخدام الناقلات كوسيلة لنقل المنتج، وهذه الناقلات إما أن تكون مملوكة أو مستأجرة للشركة. ومن هذا المنطلق أصبحت عملية الجدولة بين الملكية والاستئجار لنقل المنتج عملية شاقة ومعقدة وذات تكلفة عالية. ومن ثم أصبح استخدام النموذج الرياضي المقترح في هذه الدراسة أمر ضروري لتخفيض تكاليف النقل والتخطيط المستقبلي. إضافة إلى ذلك يزود النموذج لمتخذي القرار أداة لمعرفة الأيام المثلى لتفريغ الشحنة ووسيلة معرفة الطرق المتعددة للنقل والجدولة.
ممارسات التخطيط في منشآت الأعمال الصغيرة في دولة الإمارات العربية المتحدة (بحث قصير)
Authors: الشيخ فؤاد نجيب
Published: December 2024

هدفت هذه الدراسة إلى تقصي مدى قيام منشآت الأعمال الصغيرة في دولة الإمارات العربية المتحدة بوضع خطط قصيرة الأجل، ومعرفة الجهة/الجهات التي تقوم بعملية التخطيط، ونوع المعلومات التي تتضمنها الخطط، والعوائق التي تحول دون ممارسة التخطيط. خلصت الدراسة إلى أن معظم المنشآت الصغيرة تشير إلى وجود خطط قصيرة الأجل لديها (لمدة سنة واحدة)، ولكن تلك التي يوجد بها خطط موثقة فقط 56%. وتشير النتائج أيضاً إلى أن عملية التخطيط تتسم بالمركزية. أما أهم المعلومات التي تتضمنها الخطة في العادة فهي تلك التي تتعلق بالتنبؤ بالأرباح والمبيعات والتدفقات النقدية. وأخيراً خلصت الدراسة إلى بعض التوصيات التي من شأنها أن تدعم عملية تطوير مهارات التخطيط وتنميتها لدى القائمين على المنشآت الصغيرة.
Spatial-Temporal Patterns of Litterfall Mercury Concentration and Flux in Typical Vegetation in China
Authors: Han Shuyu , Niu Xiang , Wang Bing , Wang Zhangwei , Zhang Xiaoshan , Wang Qiang , Du Jiajie , Liu Pingping , Liu Donghuan , Pan Fengshi , Xu Tingyu
Published: December 2024

Mercury is one of the most toxic heavy metal pollutants, and mercury absorbed by plant leaves accumulates in forests in the form of litterfall. Therefore, in this study, leaf mercury concentrations and mercury fluxes were analyzed in typical sample plots of each vegetation type, which were selected from 7 geographic regions in China. The results showed that the amount of litterfall of each component varied among different vegetation types, with leaves accounting for the largest proportion (51.12% to 80.54%). The annual amount of leaf litter ranged from 3.35 to 5.50 t/(hm
2
·year). On the seasonal scale, the litterfall amount peaked in the autumn for most vegetation types. On a spatial scale, the litterfall amount displayed a decreasing trend with increasing latitude, with the highest of 8.16 ± 4.61 t/(hm
2
·year) in the southwestern China, and the lowest was 2.98 ± 0.89 t/(hm
2
·year) in north China. Moreover, leaf litter mercury concentrations ranged from 2.11 to 236.70 ng/g, with a mean value of 57.92 ± 33.07 ng/g. Leaf mercury concentrations of most tree species increased gradually with the growing period and showed a pattern of higher in the south and lower in the north on the spatial scale. Furthermore, leaf mercury fluxes of the 5 vegetation types ranged from 177.58 to 410.50 mg/(hm
2
·year), and the accumulation of mercury mainly occurred in autumn. The comprehensive quantification of mercury fluxes in this paper provides data support for the long-term monitoring of litterfall and fundamental information to potentially solve the problem of mercury pollution in China.
ECG-LM: Understanding Electrocardiogram with a Large Language Model
Authors: Yang Kai , Hong Massimo , Zhang Jiahuan , Luo Yizhen , Zhao Suyuan , Zhang Ou , Yu Xiaomao , Zhou Jiawen , Yang Liuqing , Zhang Ping , Qiao Mu , Nie Zaiqing
Published: December 2024

Background:
The electrocardiogram (ECG) is a valuable, noninvasive tool for monitoring heart-related conditions, providing critical insights. However, the interpretation of ECG data alongside patient information demands substantial medical expertise and resources. While deep learning methods help streamline this process, they often fall short in integrating patient data with ECG readings and do not provide the nuanced clinical suggestions and insights necessary for accurate diagnosis.
Methods:
Although recent advancements in multi-modal large language modeling have propelled their application scope beyond the natural language processing domain, their applicability to ECG processing remains largely unexplored, partly due to the lack of text–ECG data. To this end, we develop ECG-Language Model (ECG-LM), the first multi-modal large language model able to process natural language and understand ECG signals. The model employs a specialized ECG encoder that transforms raw ECG signals into a high-dimensional feature space, which is then aligned with the textual feature space derived from the large language model. To address the scarcity of text–ECG data, we generated text–ECG pairs by leveraging detailed ECG pattern descriptions from medical guidelines, creating a robust dataset for pre-training ECG-LM. Additionally, we fine-tune ECG-LM with public clinical conversation datasets and build an additional supervised fine-tuning dataset based on real clinical data from the hospital, aiming to provide a more comprehensive and customized user experience.
Results:
ECG-LM outperforms existing few-shot and zero-shot solutions in cardiovascular disease detection across all 3 tasks (diagnostic, rhythm, and form) while also demonstrating strong potential in ECG-related question answering.
Conclusions:
The results across various tasks demonstrate that ECG-LM effectively captures the intricate features of ECGs, showcasing its versatility in applications such as disease prediction and advanced question answering.
Advances in Nanoengineered Terahertz Technology: Generation, Modulation, and Bio-Applications
Authors: Jin Zhongwei , Lou Jing , Shu Fangzhou , Hong Zhi , Qiu Cheng-Wei
Published: December 2024

Recent advancements in nanotechnology have revolutionized terahertz (THz) technology. By enabling the creation of compact, efficient devices through nanoscale structures, such as nano-thick heterostructures, metasurfaces, and hybrid systems, these innovations offer unprecedented control over THz wave generation and modulation. This has led to substantial enhancements in THz spectroscopy, imaging, and especially bio-applications, providing higher resolution and sensitivity. This review comprehensively examines the latest advancements in nanoengineered THz technology, beginning with state-of-the-art THz generation methods based on heterostructures, metasurfaces, and hybrid systems, followed by THz modulation techniques, including both homogeneous and individual modulation. Subsequently, it explores bio-applications such as novel biosensing and biofunction techniques. Finally, it summarizes findings and reflects on future trends and challenges in the field. Each section focuses on the physical mechanisms, structural designs, and performances, aiming to provide a thorough understanding of the advancements and potential of this rapidly evolving technology domain. This review aims to provide insights into the creation of next-generation nanoscale THz devices and applications while establishing a comprehensive foundation for addressing key issues that limit the full implementation of these promising technologies in real-world scenarios.
Can Thermal Nonreciprocity Help Radiative Cooling?
Authors: Hu Run , Chen Zihe , Kim Sun-Kyung
Published: December 2024

Radiative cooling has witnessed substantial progress while its performance is constrained by the thermal reciprocal Kirchhoff’s law. Violating Kirchhoff’s law to pursue nonreciprocal radiative cooling seems promising; however, the energy conservation requirement and radiant flux integrated over the entire hemisphere make the nonreciprocal benefit insignificant. This commentary discusses the practical limits of nonreciprocal radiative cooling and points toward the future direction of directional radiative cooling.
Positive Chemotactic Flasklike Colloidal Motors Propelled by Rotary F
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F
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-ATP Synthases
Authors: Li Yue , Wu Yingjie , He Qiang
Published: December 2024

Living microorganisms can perform directed migration for foraging in response to a chemoattractant gradient. We report a biomimetic strategy that rotary F
o
F
1
-ATPase (adenosine triphosphatase)-propelled flasklike colloidal motors exhibit positive chemotaxis resembling the chemotactic behavior of bacteria. The streamlined flasklike colloidal particles are fabricated through polymerization, expansion, surface rupture, and re-polymerizing nanoemulsions composed of triblock copolymers and ribose. The as-synthesized particles enable the incorporation of thylakoid vesicles into the cavity, ensuring a geometric asymmetric nanoarchitecture. The chemical gradient in the neck channel across flasklike colloidal motors facilitates autonomous movement at a speed of 1.19 μm/s in a ΔpH value of 4. Computer simulations reveal the self-actuated flasklike colloidal motors driven by self-diffusiophoretic force. These flasklike colloidal motors display positive directional motion along an adenosine diphosphate (ADP) concentration gradient during adenosine triphosphate (ATP) synthesis. The positive chemotaxis is ascribed that the phosphorylation reaction occurring inside colloidal motors generates 2 distinct phoretic torques at the bottom and the opening owing to the diffusion of ADP, thereby a continuous reorientation motion. Such a biophysical strategy that nanosized rotary protein molecular motors propel the directional movement of a flasklike colloidal motor holds promise for designing new types of biomedical swimming nanobots.
Deep Learning-Enabled Integration of Histology and Transcriptomics for Tissue Spatial Profile Analysis
Authors: Ge Yongxin , Leng Jiake , Tang Ziyang , Wang Kanran , U Kaicheng , Zhang Sophia Meixuan , Han Sen , Zhang Yiyan , Xiang Jinxi , Yang Sen , Liu Xiang , Song Yi , Wang Xiyue , Li Yuchen , Zhao Junhan
Published: December 2024

Spatially resolved transcriptomics enable comprehensive measurement of gene expression at subcellular resolution while preserving the spatial context of the tissue microenvironment. While deep learning has shown promise in analyzing SCST datasets, most efforts have focused on sequence data and spatial localization, with limited emphasis on leveraging rich histopathological insights from staining images. We introduce GIST, a deep learning-enabled gene expression and histology integration for spatial cellular profiling. GIST employs histopathology foundation models pretrained on millions of histology images to enhance feature extraction and a hybrid graph transformer model to integrate them with transcriptome features. Validated with datasets from human lung, breast, and colorectal cancers, GIST effectively reveals spatial domains and substantially improves the accuracy of segmenting the microenvironment after denoising transcriptomics data. This enhancement enables more accurate gene expression analysis and aids in identifying prognostic marker genes, outperforming state-of-the-art deep learning methods with a total improvement of up to 49.72%. GIST provides a generalizable framework for integrating histology with spatial transcriptome analysis, revealing novel insights into spatial organization and functional dynamics.
Recent Advances in Self-Powered Sensors Based on Ionic Hydrogels
Authors: Yin Jianyu , Jia Peixue , Ren Ziqi , Zhang Qixiang , Lu Wenzhong , Yao Qianqian , Deng Mingfang , Zhou Xubin , Gao Yihua , Liu Nishuang
Published: December 2024

After years of research and development, flexible sensors are gradually evolving from the traditional “electronic” paradigm to the “ionic” dimension. Smart flexible sensors derived from the concept of ion transport are gradually emerging in the flexible electronics. In particular, ionic hydrogels have increasingly become the focus of research on flexible sensors as a result of their tunable conductivity, flexibility, biocompatibility, and self-healable capabilities. Nevertheless, the majority of existing sensors based on ionic hydrogels still mainly rely on external power sources, which greatly restrict the dexterity and convenience of their applications. Advances in energy harvesting technologies offer substantial potential toward engineering self-powered sensors. This article reviews in detail the self-powered mechanisms of ionic hydrogel self-powered sensors (IHSSs), including piezoelectric, triboelectric, ionic diode, moist-electric, thermoelectric, potentiometric transduction, and hybrid modes. At the same time, structural engineering related to device and material characteristics is discussed. Additionally, the relevant applications of IHSS toward wearable electronics, human–machine interaction, environmental monitoring, and medical diagnostics are further reviewed. Lastly, the challenges and prospective advancement of IHSS are outlined.
Man vs. Technology (Forms and Transformations of Virtualisation of Everyday Life in the Era of Transhumanism)
Authors: Moravčíková Erika , Jakubovská Viera , Jakubovská Kristína
Published: December 2024

The authors of the present study analyse various forms of virtualisation of the everyday as they appear in different theories and forms in contemporary media studies (see: Deuze, 2016; Floridi, 2019; Manovich, 2018; Lindgren et al., 2014; Gálik, 2011; Radošinská, 2021; Čábyová et al., 2024), including the transformation of physical space to cyberspace (exemplified by the virtualisation of home), social desertion via the digitisation of the self, transhumanism and the Quantified Self movement. The study is aimed at highlighting the current shift towards online culture and reflecting on some of the socio-cultural changes that are gradually establishing themselves under the influence of digitalisation and virtual forms of experience. At the same time, the authors reflect on some socio-cultural shifts from post-humanism to transhumanism. These shifts are gradually and inevitably establishing themselves under the baton of digitalisation and virtual forms of experiencing the everyday. The ambition of the text is to analyse the presence, manifestations and rise of phenomena related to the virtualisation of the everyday and socio-cultural reality as part of broader processes of digitisation (life-hacking and Quantified Self movement, transhumanism, artificial intelligence).
The Current Position of Neuromarketing as a Tool of Marketing and Communication Strategy
Authors: Pátík Ladislav
Published: December 2024

Neuromarketing is a tool used to investigate real consumer preferences that are not subjectively influenced, e.g. bias towards a certain brand, marketing communication tools, etc. It studies brain functions when deciding to buy a product. The goal is to find and identify the differences between the customer’s conscious assertion and subconscious behaviour. It monitors how the brain reacts to certain stimuli contained in an advertisement, brand, etc. For this, it uses studies that examine the influence of marketing stimuli on consumer reactions. The goal of our study is to provide an objective and comprehensive overview of new scientific findings that point to certain gaps in research methods and thinking about consumer behaviour and decision-making. We focus on the field of neuromarketing in general, on its methods, the concept of intuitive consumer behaviour. The core parts are practical applications of neuromarketing in the field of marketing and marketing communication. The research part describes the course and results of the applied experiment, using two methods of neuromarketing research to influence the senses of the consumer and to find the differences between conscious and unconscious decision-making, and at the same time, how these findings can manifest themselves in the area of marketing and communication strategy. Key findings are clearly summarised in the summary and conclusion.
AI in Communication: Theoretical Perspectives, Ethical Implications, and Emerging Competencies
Authors: Mirek-Rogowska Aleksandra , Kucza Wojciech , Gajdka Krzysztof
Published: December 2024

Artificial intelligence (AI) is rapidly transforming communication processes across various sectors, including marketing, education, healthcare, and entertainment. This study explores the theoretical perspectives surrounding AI’s integration into communication, examining how AI-driven tools such as ChatGPT, MidJourney, and Google Gemini are reshaping content creation, personalisation, and human-machine interaction. While AI enhances efficiency and allows for real-time customisation of messages, it also presents ethical challenges related to privacy, data security, and algorithmic bias. By synthesising key academic studies, the study outlines the critical ethical considerations, including the risks of deepfakes and disinformation, and emphasises the need for ethical frameworks to guide responsible AI use. The text also discusses the new digital competencies required to navigate AI-enhanced communication environments, such as AI literacy, data proficiency, and ethical reasoning. Through a systematic literature review, this study contributes to the ongoing discourse on AI’s role in communication by offering a comprehensive theoretical framework that highlights both the opportunities and limitations of AI technologies. Future research should focus on addressing gaps in empirical studies, particularly concerning the long-term impacts of AI on decision-making and the ethical governance of AI-generated content.
Loyalty Programmes as Retailers’ Communication Tools during a Period of Social Change
Authors: Kollárová Daniela , Kushnarevych Andrii
Published: December 2024

We are engaged in the study of loyalty systematically built and anchored in the form of consumer loyalty programmes. The aim of this theoretical review is to identify the problems and challenges retailers face in communicating with customers using loyalty programmes in a period of significant societal change. We examined 411 scholarly studies registered in the Web of Science database. Based on the results of the analysis, we identified the challenges faced by sponsoring organisations in the operation of modern loyalty programmes, which we divided into 14 categories by common features. The result is a compact theoretical overview about loyalty programmes. The aim of the empirical research, conducted through written inquiries and individual semi-structured interviews, is to find out how Generation Z respondents perceive loyalty programmes. The selected results reveal that there is a relatively large group of loyalty programme members who believe that they are not adequately rewarded by the sponsoring organisation.
AB Ülkelerinin Dijitalleşme Seviyelerinin Yeni Bir VIKOR Uzantısıyla Karşılaştırılması
Authors: Göktaş Furkan , Sezer Kaplan Sümeyra
Published: December 2024

Dijitalleşme kavramı gün geçtikçe önem kazanmaktadır. Bu çalışmanın amacı Avrupa Birliği (AB) ülkelerinin 2017-2022 dönemindeki dijitalleşme seviyelerinin bütüncül bir bakış açısıyla karşılaştırılmasıdır. Bu nedenle VIKOR yönteminin norm minimizasyonuna dayalı bir uzantısı (NM-VIKOR) bu çalışmada önerilmiştir ve bu uzantı grup karar verme problemleri için genelleştirilmiştir. Bu genel hal NMG-VIKOR olarak adlandırılmıştır. Bu yaklaşımlar tanımları gereği tek çözüm vermektedir. NM-VIKOR kullanılarak yapılan karşılaştırmalara göre; 2021 ve 2022 yıllarında Danimarka ilk sırada iken 2017, 2018, 2019 ve 2020 yıllarında Finlandiya ilk sıradadır. Tüm periyot için NMG-VIKOR kullanılarak yapılan karşılaştırmaya göre; Finlandiya ve Danimarka sıralaması vardır. Buna karşın diğer AB ülkeleri dijital gelişim açısından görece yetersizdir.
Biofuel Pellets as a Sustainable Energy Solution: Exploring the Role of Biomass and Regional Waste Management in Turkey's TR63 Region
Authors: Üçok Serdar
Published: December 2024

In recent years, the increasing demand for sustainable and renewable energy sources has led to significant interest in biofuels. Bifuel pellets, which combine biomass materials with fossil fuels, have emerged as an innovative and environmentally friendly energy solution. Typically made from agricultural residues, wood waste, or energy crops, blended with fossil fuels such as coal or oil derivatives, bifuel pellets offer improved energy efficiency and combustion properties. By bridging the gap between traditional fossil fuels and renewable energy alternatives, bifuel pellets provide a transitional solution that enhances both calorific value and combustion efficiency. The dual composition of these pellets allows for better adaptation to existing energy infrastructures while supporting reductions in greenhouse gas emissions. In Türkiye, regional development and waste management strategies have been shaped by the adoption of the Nomenclature of Territorial Units for Statistics (NUTS) system since 2002. The TR63 NUTS Level 2 Region, which includes the provinces of Hatay, Kahramanmaraş, and Osmaniye, plays a critical role in agriculture and livestock production. Due to these activities, the region contributes significantly to waste generation. This research highlights the potential of bifuel pellets as a viable energy option for the TR63 Region, where agricultural and livestock residues could serve as essential feedstock for sustainable energy production. The integration of bifuel pellets into regional energy policies could help address environmental goals while reducing dependence on conventional fossil fuels.
Экономическая политика и формула Клифта
Authors: Луценко С.И.
Published: December 2024

Автор рассматривает экономическую политику российского государства в контексте конституционного принципа социального государства. К сожалению, макроэкономическая стратегия продолжает реализовываться в рамках «Вашингтонского консенсуса». Предлагается методология - аналитический подход при выборе и реализации государством экономической политики с помощью формулы Клифта (встраивания важных показателей в эконометрическую модель).

The author examines the economic policy of the Russian state in the context of the constitutional principle of the social state. Unfortunately, the macroeconomic strategy continues to be implemented within the framework of the «Washington Consensus». A methodology is proposed - an analytical approach to the selection and implementation of economic policy by the state using the Clift formula (embedding important indicators in an econometric model).
Transformando desafios cotidianos em oportunidades de aprendizagem: projetos de robótica na educação profissional com suporte do ChatGPT
Authors: Paiva Tatiana Vieira dos Santos , Sant'Ana Claudinei De Camargo
Published: December 2024

Este relato descreve o desenvolvimento de projetos de robótica com suporte de uma Inteligência Artificial (IA) a partir de situações-problema da comunidade escolar, realizado com estudantes da segunda série de um Curso Técnico em Informática Integrado da cidade de Vitória da Conquista, na Bahia. A atividade foi desenvolvida em três etapas: apresentação do problema, criação do circuito, construção e apresentação da maquete no pátio da escola. O ChatGPT foi utilizado nas três fases para correção do objetivo e apoiar na solução de problemas que surgiram na montagem dos circuitos e na elaboração dos códigos. A produção dos dados foi feita através dos registros da professora, de formulários eletrônicos, dos recortes de diálogos com a IA e das maquetes criadas. Os resultados demonstraram habilidades como autonomia, uso consciente e crítico das tecnologias, aplicações reais da linguagem de programação, conhecimentos na montagem de circuitos com elaboração dos códigos do Arduino e utilização da IA como um assistente no desenvolvimento dos trabalhos. Os estudantes também consideraram ter atingido os objetivos e se sentiram satisfeitos com os resultados.
Insistencias de la manifestación feminista: pulso, agenda y masividad en la ciudad de La Plata
Authors: Esquivel Juliana
Published: December 2024

Este trabajo caracteriza la conflictividad social feminista a partir de un análisis de las manifestaciones sucedidas entre el 8 de marzo de 2001 y el 26 de diciembre de 2019 en la ciudad de La Plata. Tomo estos años como límites del análisis porque, en ambos, la ciudad fue sede de enormes manifestaciones en el marco del Encuentro Nacional de Mujeres, en  2001 y del Encontrolazo y el Encuentro Plurinacional de Mujeres, Lesbianas, Travestis, Trans, Bisexuales y no Binaries, en 2019. La organización de estos Encuentros ha presentado desafíos para el activismo local por la gestión que implican y han sido instancias de aumento en la visibilidad de sus consignas y demandas. Respecto del enfoque de este artículo, han significado un salto de escala en las manifestaciones de la ciudad. Por eso, los he elegido como los años límites de esta periodización. Teniendo en cuenta lo anterior, aquí analizo el pulso de la conflictividad a partir de la cantidad de manifestaciones por año mostrando que aquello que se suele caracterizar como la “cuarta ola” del feminismo fue un aumento del número de manifestaciones por año y de manifestantes sólo en algunas protestas. Señalo que la intensificación entre 2015 y 2019 no fue la única del período, sino que existieron dos momentos previos: el año 2007 y los años 2011 y 2012. Para comprender esos momentos de alza en la conflictividad, abordo la agenda del activismo local y muestro que las fechas de movilización fueron mayormente efemérides locales, federales e internacionales y fechas relevantes para ciertos casos singulares de violencias de género, cisexistas y heteronormadas de la región. Por último, me refiero a la masividad en algunas manifestaciones a la luz de la bibliografía acerca de la “cuarta ola” en Argentina. Argumento que, más que una serie de acciones siempre masivas, existieron tan sólo algunas con esas características.
Sentidos en disputa sobre el 25N de 2023 bajo el ascenso de la “nueva derecha”: redes sociales y medios de comunicación de Mendoza y Córdoba
Authors: Gil Ana Soledad , Aráoz Verónica
Published: December 2024

Desde 1981, el 25 de noviembre (25N), o Día Internacional de la Eliminación de la violencia contra las Mujeres, es una fecha insoslayable para los feminismos. Consideramos que, en Argentina, desde 2015 a 2020, el 25N quedó subsumido a otras reivindicaciones como: Ni Una Menos, los debates por la despenalización y legalización del aborto y los paros internacionales de mujeres y diversidades. La pandemia profundizó desigualdades y el temor por el incremento de las violencias de género, asunto que adquirió centralidad y reposicionó al 25N en la agenda feminista. Postpandemia, los mensajes feministas tuvieron un corrimiento de sentido al interpelar a las extremas derechas. Creemos que los feminismos se han convertido en opositores clave en la disputa de sentidos en un contexto de proliferación de discursos de odio hacia estos. En este trabajo analizamos narrativas, decires y construcciones de sentido en cuentas oficiales de Instagram de colectivas feministas, alrededor del 25N. También, la puesta en discurso sobre el tópico, en dos diarios hegemónicos de las provincias de Córdoba y de Mendoza, La Voz del Interior y Los Andes. Nuestra pesquisa asume aportes feministas del punto de vista y conocimiento situado y herramientas del análisis del discurso crítico y social.
Combining a thorough medical examination and the use of makeup in aesthetic medicine to achieve optimal results of appearance correction (literature review)
Authors: Dovzhanyn Y.V.
Published: December 2024

Aesthetic medicine is aimed at improving the appearance of aesthetic seekers using comprehensive methods, such as the integration of clinical medicine and body aesthetics. With the growing demand for social aesthetics, the field of aesthetic medicine continues to seek new ways to achieve optimal results. Therefore, the purpose of the work was to determine the role of combining a thorough medical examination with the use of makeup in aesthetic medicine to achieve optimal results of appearance correction. Modern possibilities of aesthetic medicine, in particular the use of makeup, allow to maintain and preserve the beauty and health of the skin, to carry out appearance correction and help eliminate signs of aging. At the same time, the doctor is obliged to provide the patient with proper impeccable service and guarantee that it will lead to the desired effect. To this end, aesthetic medicine offers a wide range of treatment options, from conventional skin care and injections to laser therapy. The introduction of nanotechnology has contributed to progress in cosmetics, which has led to an increase in consumer demand for it worldwide. The use of nanomaterials in aesthetic medicine allows overcoming some of the disadvantages of using traditional cosmetic products: some problems of stability, toxicity, etc. It has been determined that before performing a cosmetic procedure, the doctor is obliged to provide the patient with full information about the possible side effects of their use. Conducting a thorough medical examination, improving professional skills and safety in aesthetic medicine and makeup can reduce complications, contribute to increased patient satisfaction, ensure the safety of the medical aesthetic process and achieve optimal results in appearance correction.

Keywords: cosmetic products, body aesthetics, effectiveness, risks.