bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of vascular injury within the conditions of choline deficiency in rats with scopolamine-induced alzheimer's type dementia
Authors: Gubina-Vakulik G.I. , Zorenko Y.M.
Published: December 2021

Background. The relationship between choline deficiency and vascular dysfunction continues to be relevant in the study of Alzheimer's disease. Objective. To study the morphological characteristics of vascular injury within the conditions of choline deficiency in rats with scopolamine-induced Alzheimer's type dementia. Methods. The experiment was performed on 48 WAG population male rats weighing 180-230 gr. Rats from groups Scop-14, Scop-14-SC, Scop-28, Scop-28-SC were injected intraperitoneally with scopolamine (Scop) butylbromide at a dosage of 1 mg/kg of body mass during 14 and 28 days and intravenously with mesenchymal stem cells (SC) at a single dosage of 500000 cells per 1 rat. Control animals (gr.C) were injected with 0.9% sodium chloride. Brain slides were stained with Congo-red and gallocyanine-chromium alum according to Einarson's method for total nucleic acids. The VEGF, E-cadherin expression was immunohistochemically determined in the brain cells cytoplasm. Results. The congophilic staining of the arteries walls, a decrease in endothelial cells with low the E-cadherin expression and an increase in the number of pericytes in the capillary wall was observed in the experimental groups. In gr.Scop-28 VEGF expression in endothelial cells, hippocampal neurons was greater than in gr.Scop-14. It indicated more intensive activation of angiogenesis and acetylcholine synthesis with correspondingly more pronounced vascular damage and choline deficiency. The cytoplasm of cortical neurons was diffusely labeled with VEGF antibodies in response to hypoxia, but the level of expression was almost no different from that in gr.C. In all groups, the optical density of the neuropile of the large hemispheres according to Einarson’s staining was reduced, i.e., the level of RNA in the neuronal processes was reduced. The introduction of stem cells restored the capillary wall due to young endothelial cells, reduced the VEFG synthesis in all studied cells and increased the RNA content in neuronal processes. Conclusion. The relationship between choline deficiency, neuronal process loss and vascular damage has been found. The blood vessels self-repair was occurred by substitution, after the stem cells introduction - by restitution.
Features of morphological changes in articular tissues in vascular diseases of the lower extremities
Authors: Zherebkin V.V. , Shiyan D.N. , Borzenkova I.V. , Tkachenko P.V.
Published: December 2021

Background. Big epidemiological studies have revealed a link between osteoarthritis and some cardiovascular diseases such as coronary heart disease, heart failure, cerebral circulation disorders, vascular diseases and diabetes mellitus. Objective. Determination of the features of morphological changes in the synovial membrane of the joint, articular cartilage and subchondral bone in patients with cardiovascular diseases. Methods. Histological studies of articular tissues of 30 amputated lower extremities in persons with vascular diseases of the lower extremities were performed. Results. In all samples of the capsule of the knee joint, gross violations of the microcirculatory canal and histological changes of osteoarthritis and subchondral osteoporosis were revealed. At the same time, the revealed changes in the articular cartilage and subchondral bone were more pronounced in the patellar, which in the knee joint carries a negligible functional load, but receives blood supply only from the vessels of the articular capsule than in the joint surface of tibia, carrying the lion's share of the functional load on the knee joint, but receiving blood supply from the posterior tibial artery. Conclusion. The revealed features of morphological changes in articular tissues in vascular diseases of the lower extremities indicate that these diseases play an important role in the development of osteoarthritis and are more significant than the functional load on the joint. Further studies of the features of morphological changes in articular tissues in the samples of various contingents of persons are needed.
Ultrastructural characteristics of the rats laryngeal mucosa and cartilage on the 7 and 14 days of the experimental opioid effect
Authors: Ivasivka K.P. , Paltov Ye.V. , Masna Z.Z. , Chelpanova I.V. , Dudok O.V.
Published: December 2021

Background and objective. Our main task was to study the ultrastructural organization of the laryngeal mucosa and cartilage on the seventh and fourteenth day of opioid exposure. Methods. The material for the study were mature, outbred male rats in the number of 32 animals, weighing 80g, aged 4.5 months. Animals were injected intramuscularly with Nalbuphine once a day at the same time (10-11 hours in the morning) for 14 days. The initial dose of Nalbuphine was 8 mg / kg during the first week, 15 mg / kg during the second week of the experimental study. Thus, we created the conditions for chronic opioid exposure. Animals were divided into 3 experimental groups: 1 – control group; 2 - animals that received the drug for 7 days; 3 - animals that received the drug for 14 days). All animals were kept in a vivarium. Animal care, labeling and all other manipulations were carried out taking into account the issues of bioethical norms. Before collecting necropsy material, the animal was removed from the experiment with diethyl ether. The the larynx mucosa and rats cartilage were used as the material for ultrastructural examination. Ultrastructural capsule was prepared according to conventional methods. Results. As a result of experimental opioid exposure at the end of 7 days we found alternative changes in the epithelial cells of different parts of the larynx, dyscirculatory changes in blood vessels of lamina propria and submucosa, as well as the destruction of chondrocytes of hyaline and elastic cartilages. The hemocapillaries of lamina propria and submucosa, especially in the ventricles of the larynx and in the subchondral region, were dilated, overflowing with erythrocytes. In the laryngeal mucosa and submucosal base of the laryngeal ventricles, in addition to the overflow of hemocapillaries with erythrocytes, a moderate accumulation of perivascular transudate was noted. At the end of the 14th day of the experimental opioid effect, a pronounced hemocapillaries injury was found, which was accompanied by an increase in the permeability of the vascular wall. In addition to blood plasma, erythrocytes were visualized in the enlarged lumens of hemocapillaries. The development of degenerative changes of endothelial cells, which were accompanied by inhomogeneous dilation of the tubules of the smooth and granular endoplasmic reticulum, was noted. The main substance of the connective tissue of the mucous membrane and submucosal base, especially around the vessels was impregnated with transudate.
The impact of perindopril and metformin on the markers of endothelial dysfunction in rats with acute intracerebral hemorrhage and type 2 diabetes mellitus
Authors: Zhyliuk V.I. , Lievykh A.E. , Shevtsova A.I. , Tkachenko V.A. , Kharchenko Yu.V.
Published: December 2021

This comparative research is aimed to study the effect of perindopril and metformin on the levels of biochemical markers of endothelial dysfunction in rats with type 2 diabetes mellitus (T2DM) complicated by a brain hemorrhage. The study was carried out on 30 white male Wistar rats. T2DM was simulated by a single intraperitoneal injection of nicotinamide and streptozotocin (NA/STZ). Intracerebral hemorrhage (ICH) was induced by microinjection of 1 μL of bacterial collagenase 0.2 IU/μL into the striatum on the 60th day of the experiment. Animals were randomized into 5 groups: A – negative control (intact, n=6); B – positive control 1 (NA/STZ, n=6); C – positive control 2 (NA/STZ+ICH, n=6); D – perindopril (“Prestarium”, 2 mg/kg+NA/STZ+ICH, n=6); E – metformin (“Siofor”, 250 mg/kg+NA/STZ+ICH, n=6). The studied drugs were administered intragastrically for 20 days, starting from the 50th day after the induction of T2DM. Endothelial function was assessed by the content of homocysteine (Hcy), advanced glycation end products (AGEs), endothelin-1 (ET-1), and von Willebrand factor (vWF) in blood serum. It was found that long-term separate T2DM is accompanied by hyperhomocysteinemia, as well as an increase in AGEs, ET-1, and vWF levels, indicating dysregulation of the hemostasis system and vascular tone. It should be noted that brain hemorrhage in T2DM can enhance these manifestations, although the obtained differences were characterized only by a persistent trend. At the same time, the effect of perindopril was limited only by a significant decrease in AGEs levels by 31.2% (p<0.05). In turn, the action of metformin was characterized by a positive glycemic control, as well as an effect on the state of the vascular endothelium, namely, a significant decrease in AGEs, ET-1 and vWF levels by 37.6% (p<0.05); 5.5% (p<0.05) and 9.5% (p<0.05), respectively. It was also found that the endotheliotropic properties of the studied drugs were not associated with an effect on homocysteine levels. Thus, metformin in conditions of diabetes mellitus complicated by acute intracerebral hemorrhage has advantages over perindopril in relation to endothelial dysfunction.
Advanced glycation end products, galectin-3, matrix metalloproteinase-9 activity in men with heart failure and concomitant benign prostatic hyperplasia with androgen deficiency
Authors: Nedzvetsky V.S. , Sirenko O.Yu. , Tkachenko V.A. , Kuryata O.V.
Published: December 2021

The aim was to evaluate serum levels of matrix metalloproteinases-9 activity, advanced glycation end products, galectin-3, C-reactive protein in men with heart failure and benign prostatic hyperplasiawith testosterone deficiency. The testosterone level was determined by immune-enzyme analysis. The content of advanced glycation end products in plasma were analysed by quantitative autofluorescence. The metalloproteinases-9 activity was estimated with fluorometry. The level of galectin-3, C-reactive protein was determined by immune-enzyme analysis. 1st group was made up by the men with heart failure and benign prostatic hyperplasia with testosterone deficiency; 2nd group – by the men without testosterone deficiency. The men with heart failure and benign prostatic hyperplasia with testosterone deficiency had a significantly higher level of advanced glycation end products, galectin-3, matrix metalloproteinases-9 activity in comparison with men with heart failure without testosterone deficiency (p<0.001). Correlation relations between serum advanced glycation end products in patients of the main group with age, ejection fraction, testosterone level were determined – r=0.48 (p<0.001), r=-0.62 (p<0.001), r= -0.66 (p<0.001) respectively. Receiver operating characteristic analysis for predictive role in heart failure with preserved ejection fraction have shown high degree of sensitivity and specificity for advanced glycation end products in serum (p<0.001). Middle-aged men with heart failure with preserved ejection fraction and benign prostatic hyperplasia with testosterone deficiency are characterised by increased serum advanced glycation end products, galectin-3, matrix metalloproteinases-9 activity, C-reactive protein. Serum advanced glycation end products are potential biomarkers of development of heart failure with phenotype of preserved ejection fraction in this cohort.
Assessment of correction effectivenes of psychoemitional state in pregnant women after application of assisted reproductive technologies
Authors: Beniuk V.O. , Ginzburg V.G. , Vygivska L.M. , Maidannyk I.V. , Chorna O.O. , Oleshko V.F. , Marushchenko Yu.L. , Lastovetska L.D.
Published: December 2021

To determine the role and effectiveness of the proposed the­rapeutic and preventive complex in the correction of psychoemotional state in the dynamics of pregnancy in pregnant women after assisted reproductive technologies (ART) application in order to improve the tactics of antenatal obser­vation and prevention of obstetric and perinatal complications. 299 pregnant women were comprehensively examined and a set of therapeutic and preventive measures was carried out: the main group included 249 women whose pregnancy occurred as a result of ART application. The control group consisted of 50 pregnant women with spon­taneous pregnancy. The complex of measures for pregnant women after ART application included: micronized pro­gesterone, magnesium oxide, folic acid, L-arginine aspartate, Omega-3 polyunsaturated fatty acids and long-term psychological correction – before ART program, at 8-10 weeks of pregnancy, at 16-18 weeks of pregnancy and at 28-30 weeks of pregnancy. Introduction of the proposed complex of psychoemotional correction contributed to the formation of reactive anxiety and personal anxiety levels at a moderate level in women of subgroups IA-44 (89.8%) and 43 (87.6%), IIA – 43 (89.6%) and 44 (91.7%) and IIIA – 30 (83.3%) and 26 (72.2%), which is considered to be an adaptive, physiological type during pregnancy. The positive effect of the proposed complex of psychoemotional correction demonstrates the improvement of processes of formation of type of component gestational dominant, its return to the optimal type in women of subgroup IA – 41 (83.6%), IIA – 39 (81.3%) and IIIA – 26 (72.2%) that is close to the physiological course of pregnancy and contributes to the reduction of perinatal and obstetric complications among pregnant women of these subgroups.
Nonspecific protective factors in patients with early latent syphilis (report 1)
Authors: Zakharov  S.V. , Zakharov V.K.
Published: December 2021

The objective of this work is to study nonspecific protective factors in patients with latent early syphilis. The results of the study are based on the data of a comprehensive examination before treatment of 142 patients with early latent syphilis and 20 patients of the comparison group. Methods of investigation: serological methods for the diagnosis of syphilis complex of serological reactions, enzyme-linked immunosorbent assay (IgM, IgG), Indirect immunofluorescence reaction (RIF) RIF-200, RIF-abs; determination of cytokines IL-2, IL-6, IL-10, TNFα and INFγ in blood serum by enzyme-linked immunosorbent assay; determination of the phenotype of lymphocytes (CD-receptors), the concentration of circulating immune complexes, phagocytic number, phagocytic index, Nitroblue tetrazolium test. In the blood serum of patients the concentration of IL-2, IL-6, IL-10 and TNFα, INFγ was significantly increased. The concentration of IL-10 and IL-6 was also significantly increased in patients with more than 1 year of infection. The most significant disorders of the parameters of the metabolic activity of neutrophils were found in patients with an infection of more than 1 year; an imbalance in the circulating immune complexes concentration was also established. Under the increasing duration of the infection, the concentration of CD16+ in the blood serum progressively decreases. The content of pro-inflammatory and anti-inflammatory cytokines in the blood serum of patients with early latent syphilis was significantly increased and depended on the timing of infection. This relationship was most pronounced for IL-6 and IL-10. In patients with early latent syphilis there is also an imbalance between CD25+ and late activation factor HLA-DR against the background of a progressive decrease in the number of CD16+ lymphocytes. A direct relationship was established between the time of infection and the number of NK-cells. The revealed disorders may be the consequence of significant disorders on the part of neutrophils and may be one of the factors of the latent course of syphilitic infection.
Hygienic characteristic of the electromagnetic situation created by the electromagnetic radiation of the antennas of mobile base stations in Cherkasy region before and after the introduction of 4G technology
Authors:  Halak S.S. , Dumansky V.Yu. , Nikitina N.G. , Bitkin S.V. , Bezverkha A.P.
Published: December 2021

This work is part of our researches to study the distribution of electromagnetic radiation from mobile base stations in populated areas. The aim of this work was to study and analyze the electromagnetic situation before and after the introduction of fourth generation 4G technology at mobile base stations. We analyzed the maximum and average levels of electromagnetic radiation from mobile base stations located in Cherkasy region. The electromagnetic situation was studied both in urban areas and in rural areas. It was found that after the introduction of the fourth generation 4G technology at the mobile base stations, the levels of electromagnetic radiation in Cherkasy region increased significantly. The median of maximum levels of electromagnetic radiation increased by 155.6% (in particular, in urban areas by 194.1%), and the median of average levels - by 75.2% (in particular, in urban areas by 141.1%). No significant changes in electromagnetic radiation levels were detected before and after the modernization of mobile base stations in rural areas. It has been proven that there are no prerequisites for increasing the maximum permissible level to 100 μW/cm2 when implementing 4G and 5G technologies at mobile base stations.
A look at the problem of exposure of the population caused by X-ray diagnostics: approaches to analysis and forecasting
Authors:  Sevalnev A.I. , Kutsak A.V. , Sharavara L.P. , Volkova Yu.V.
Published: December 2021

The article is devoted to the analysis of limitation of dose load on the population as a result of radiological researches. It is especially actual and represents rather high scientific and practical interest. In this regard, it is very important to have information about the state of the dose load of the population in separate regions and to rank types of diagnostics by the amount of their contribution to the total dose of medical exposure. The aim of the work was to study the state of dose load of the population of Zaporizhzhia region due to X-ray diagnostics, to develop approaches to analysis and forecasting regarding its limitation. Analytical, statistical calculation and logical generalization methods were used in the course of the work. We used the results of studies carried out in accordance with the regional “Program for the Protection of the Population of Zaporizhzhia Region from the Effect of Ionizing Radiation. The authors analyzed scientific publications (15 sources), including 9 Ukrainian and 6 foreign on the relevance of the problem of exposure of the population caused by X-ray diagnostics. The analysis of the results allowed to determine that in 2010-2014 the radiation dose of the population of Zaporizhzhia region due to X-ray diagnostics averaged 0.92 mSv year-1, in 2015-2016 the dose increased and amounted to 0.96 mSv year-1. The proposed approach to the analysis makes it possible to summarize and model data on radiological studies of the population over a long period of time, to identify persistent trends in the contribution of different types of radiation diagnostics to the dose of medical radiation. All this is necessary for the development, first of all, of measures to reduce the frequency of radiography, its replacement by other diagnostic methods. Priority tasks aimed at reducing the dose load of the population due to X-ray examinations are proposed.
Elemental state of the organism of workers and population as manifestation of adaptation to the technogenic effect of metals: new methodological approaches
Authors:  Andrusyshyna I.М.
Published: December 2021

The problem of adaptive, prepathological and pathological reactions of the body to the action of exogenous chemicals is closely intersected with the assessment of the norm and its fluctuations. The imbalance of chemical elements in the human body directly affects the functioning of almost all organs and systems, causing significant stress of adaptation mechanisms. In this article we study the elemental state of the human body depending on the physiological state (endocrine pathology and professional contact with heavy metals), analyze the correlation between macro- and microelements and assess the degree of adaptability of the body. In the work the elemental state of the human body, taking into account not only the absolute values of the concentrations of elements in the hair and whole blood was studied, the adaptability of the body according to the indicators of elemental imbalance in the blood and hair of volunteers, individuals with endocrine pathology (autoimmune thyroiditis and type II diabetes mellitus) and for those working in conditions of contact with heavy metals (for jewelers, welders and batterymen) is analyzed. The results of the study indicate that various non-specific adaptation reactions are accompanied by changes in the elemental state of a person. Under the prevailing pathology of the endocrine system (diabetes mellitus or autoimmune thyroiditis), the adaptation of the body was determined as a stage of tension and is associated with the duration of the disease. In persons exposed to professional contact with heavy metals (Mn, Cr, Pb, Ag), adaptation depended on the nature and duration of professional contact with them: the highest tension of adaptation processes was found in jewelers, and the least in welders and batterymen, which is associated with the duration of professional contact with these metals. The high number of connections between the elements indicates the tension of adaptive reactions in people with endocrine pathology and especially in jewelry workers. Adaptation to the high content of metals in the air of welders and batteries due to the longer experience of these workers and adaptation to production conditions with a decrease in the number of correlations between the elements, as a means of reliable operation.
Allergic march in children of Ukraine
Authors: Volosovets  О.P. , Bolbot Yu.K. , Beketova G.V. , Berezenko V.S. , Umanets T.R. , Rechkina O.O. , Міtiuriaeva-Korniyko I.O. , Volosovets T.М. , Churylina A.V.
Published: December 2021

Allergic diseases, which have a certain stage in their development from food allergy to bronchial asthma / allergic rhinitis, are much more common in children than in adults. The aim of this study was to analyze data on the prevalence and incidence of atopic dermatitis, bronchial asthma and allergic rhinitis as components of the allergic march, in children of Ukraine from 1994 to 2017 to determine the possible impact of adverse environmental factors on their development. During the same period, due to the influence of a number of factors, in particular environmental, there were significant changes in the structure of allergic diseases making up the stages of the allergic march due to an increase in the proportion of allergic rhinitis with the reduced one of asthma and atopic dermatitis. Within 24 years, the incidence of atopic dermatitis in children aged 0-6 years including, increased by 27.6%, in adolescents - by 40.5% and significantly decreased by 39.5% in children aged 7-14 years including. Most cases of allergic rhinitis and bronchial asthma were observed in schoolchildren (47.6 and 54.0%, respectively) with a slight decrease compared to 1994. In general, allergic diseases in recent years have become more common in children from 0 to 6 years and their detection has decreased in school-age children and adolescents. Over the past 24 years, in children of Ukraine a steady increase in the incidence and prevalence of allergic diseases that form an allergic march has been noted: the prevalence of bronchial asthma has increased by 69.3% and the incidence has increased by 22.9%; the prevalence of atopic dermatitis increased by 43.9% and the incidence increased by 8.3%; the prevalence of allergic rhinitis increased by 488.3% and the incidence of allergic rhinitis increased by 380.3%, with a predominance of detection of this pathology in children from regions with developed infrastructure and industry, where there are significant emissions of pollutants into the atmosphere, that have a direct moderate effect on the increase in the prevalence of bronchial asthma, the incidence and prevalence of allergic rhinitis in children.
Occupational stress in healthcare workers during a COVID-19 pandemic
Authors: Pinchuk  I.Y. , Pishel V.Y. , Polyvianaia M.Y. , Yachnik Y.V. , Virchenko V.V.
Published: December 2021

Healthcare workers experience overwhelming occupational and psycho-emotional stress during COVID-19 pandemic. Occupational stress leads to emotional burnout, can cause anxiety, depression and other psychopathological symptoms, influencing the quality of medical care. Existing situation necessitates to define risk factors, influencing occupational stress in healthcare workers in order to develop ways and methods to overcome it. Aim of the study was to identify socio-psychological factors associated with occupational stress in healthcare workers during the COVID-19 epidemic in Ukraine. Using a specially designed questionnaire, an online survey of 1,100 medical workers was conducted in all regions of Ukraine. Questioning was carried out over three weeks from 30.03.2020 to 21.04.2020, during the period of quarantine. The majority of respondents were female medical workers (79.9%). Age of respondents: up to 30 years – 179 (16.2%), from 31 to 60 – 824 (75.0%), over 60 – 97 (8.8%), among them doctors – 695 (63.1%) 236 nurses (21.5%), more than a third are general practitioners. Direct care for patients with COVID-19 was provided by 170 (15.5%) medical personnel. The analysis of the results of the questionnaire enabled to determine the peculiarities of medical worker`s response to the situation in connection with COVID-19 and highlight the emotional and behavioral factors associated with stress that are significant for most respondents. The study answered the questions regarding the perceived risk associated with the spread, contamination and death related to coronavirus. The most significant factors affecting the occurrence of stress in medical workers are identified. Along with this, factors contributing to stress coping have been identified as well. For subsequent statistical processing, all respondents were divided into two groups depending on the severity of the anxiety/fear. Comparison of these groups by socio-demographic indicators was done using the test χ2. There were no statistically significant differences between groups in all socio-demographic indicators, except for age. That is, only the age factor affected the severity of anxiety/fear among healthcare workers due to COVID-19 (p<0.05). Comparative analysis to assess the severity of stress in groups was performed using the Mann-Whitney U test. Healthcare workers with severe anxiety/fear have a high risk for development of occupational stress during a COVID-19 pandemic (p<0.01). In conclusion, the need for the development and implementation of methods for the prevention of occupational stress in medical workers in the current epidemic situation is substantiated.
Self Care Profile of Diabetic Patient during Covid 19 Pandemic in Manggarai Regency, East Nusa Tenggara
Authors: Wea Lidwina Dewiyanti , Simonb Maria Getrida , F.Jeharutc Aldegonda , Padutd Rosalia , K.Danue Viktoria , Bataf V.C Agnes
Published: December 2021

Diabetes mellitus (DM) is one of the comorbid diseases commonly found on COVID-19 infected individuals and causing the most death. In the pandemic era, DM patients are needful to execute the care management by themselves due to the social restriction as a part of transmission control. This study aimed to assess the self-care behavior of DM patients during the COVID-19 pandemic era in Manggarai Regency who still carry out various traditional ceremonies even during the pandemic. This study was a quantitative descriptive study. The research data get by the SDSCA (The Summary of Self-Care Activities) questionnaire developed by the General Service Administration (GSA) Regulatory Information Service Center (RISC). This study attends from January to March 2021, with 88 respondents have participated after being recruited using purposive sampling and inclusion criteria. Among the 88 respondents, the respondents were most compliant with eating restrictions on sugar-contained food such as cake, chocolate, biscuit, and ice cream diet. Respondents did not restrict themself to consume carbohydrate contained foods. Self-care behavior is most important to DM patients in the pandemic era due to the social restrictions creating the hesitancy among the patients to come to the health care facilities. Moreover, when DM patients are more prone to develop severe symptoms of covid-19. Health professionals have to improve the health education to the patients by emphasizing the importance of exercise, diabetic foot care, and routine blood sugar monitoring so that the patients are not only focused on dietary management and medicine.
Level of Online Learning Motivation in Ners Professional Students in Online Learning at University Muhammadiyah Malang
Authors: Harini Ririn , Juwitasari Juwitasari
Published: December 2021

Background: Since the covid-19 pandemic occurred at the end of 2019, the education process which is usually carried out face-to-face must be done through online learning. Due to this pandemic condition, it is still difficult for Nurse Profession level students to adapt. This study was determined the level of learning motivation during online learning at the University of Muhammadiyah Malang. Method: This descriptive analytical study was analyzed by a IBM SPSS 26 version for windows. The number of respondents as many as 78 students of ners 22 class and ners 23 class was recruited by total sampling from October 2020 - January 18, 2021. The level of motivation data was identified by the Watsin questionnaire using whatsapp, zoom and google meet online platforms. Results: The 19 respondents or about 25% of participants was less than and equal to 19 years old, 22 peoples or about 28% of student nurses aged 20 years, 19 peoples or about 24% of nursing students aged 21 years, and the remaining 18 peoples or about 23% of student aged 22 years and over. The descriptive analysis showed that the average level of motivation of Nurse students during online learning was 63,14. Conclusion: the level of motivation of Nursing students during online learning in hospitals during the COVID-19 pandemic was categorized in sufficient level. The further strengthens was the needs of variety online learning model towards nursing professional level during pandemic of COVID 19.
The Corelation of Compliance to Use PPE (Mask) and The Event of Respiratory Disorders in Workers in Bukit Kapur Jaddih, Parseh Village, Socah District, Bangkalan Regency
Authors: Suminar Ervi , Nikmah Nurun , Sari Levi Tina , Wibisono Wahyu
Published: December 2021

The process of limestone mining will resulted in limestone dust on the working environment. This can lead to inhalation of the limestone dust which can cause respiratory problems.The type of the research was analytic with Cross Sectional design. The population was all workers in Bukit Kapur Jaddih, Parseh Village, Socah District; 52 workers. The sample was 45 workers taken by simple random sampling technique. The independent variable was compliance to use mask protective equipment, while the dependent variable was respiratory disorders. The data was collected by questionnaires and observation physical observation. Â The data was analyzed using Lambda test, with Î±= 0.05.The results of the research showed that workers who did not use PPE (masks) were 35 workers (77.8%), who experienced respiratory problems were Â 39 workers (86.7%), and 6 workers (13.3%) did not experience respiratory problems. The lambda test results p Value of 0.073>Î± (0.05) meant that H0 was accepted and H1 was rejected. The compliance to use personal protective equipment (masks) and the presence of respiratory problems showed no correlation. For this reason, workers must continue to use masks while working to protect themselves from the effects of occupational breathing (lime dust).
The Effect of Behavioral Therapy with Modeling Techniques on Changes in the Adherence of Diabetes Mellitus Patients
Authors: Sulistyana Caturia Sasti , Kristiani Rina Budi
Published: December 2021

Diabetes Mellitus (DM) is a disease whose prevalence is not infectious increases with changes in lifestyle. If not managed properly, it will cause various complications that reduce quality of life, increase morbidity and mortality, and harm the economy. The success of DM management is strongly influenced by the patient's adherence to medication and diet. One of the interventions to improve the adherence of DM sufferers is Behavior Therapy with modeling techniques. The purpose of this study was to analyze the effect of behavioral therapy with modeling techniques on changes in adherence of DM patients. The design of this study was quasy-experimental with pretest posttest and control group, on a sample of 40 DM patients with consecutive sampling technique. The intervention was carried out in 4 sessions for 2 weeks. The results of the statistical test paired sample t-test and independent sample t-test obtained p <0.5 (0.000), which meant that there was an effect of behavioral therapy with modeling techniques on changes in adherence DM patient. Changes in compliance that occurred between before and after the intervention was 16.95 points. Modeling technique is behavioral learning through observation of a model who has successfully controlled his illness to emphasize changes in mindset, beliefs, and commitment to a person's new positive behavior. Modeling has an impact not only on imitating, but also adding or subtracting the observed behavior, so that it can be applied to obtain new behavior, leave old negative behavior, and maintain the desired behavior.
The Correlation of Maternal Age and the Incidence of Preeclampsia at Aura Syifa Hospital
Authors: Sari Anggita Retno , Titisari Ira , Sendra Eny
Published: December 2021

Preeclampsia is a condition when hypertension and proteinuria occurs after 20 weeks of pregnancy. The exact cause of preeclampsia is currently unknown, but many factors influence the occurrence of preeclampsia, especially the age factor. This study was aimed to determine the correlation between maternal age and the incidence of preeclampsia. This study was analytical survey designed with retrospective study method. From Aura Syifa hospital, 142 medical records in of pregnant women in 2017 were taken 105 samples by using simple random sampling technique. The result of this study indicated that delivered mothers who were in reproductive age (20-35 years old), 25.8% of them had preeclampsia and 31,1% had severe preeclampsia. The data analyzed by suing chi-square correlation and the result was Ï (0.00) < Î± (0.05) which meant that there was a correlation between maternal age and the incidence of preeclampsia. It would be better for couples planning pregnancy in healthy reproductive age for minimize the risk of preeclampsia.
Risk Factors of Breast Cancer based on Case-Control Study in Women of Child-Bearing Age (WEBA) at Gambiran Hospital Kediri
Authors: Putri Nurita Nilasari Bunga Kharisma Arifiana , Wulaningtyas Eko Sri
Published: December 2021

Breast cancer is a type of cancer that starts in the breast tissue and spreads throughout the body. Every year more than 185,000 women are diagnosed with breast cancer. This incidence is increasing in developed countries (Kemenkes RI, 2015). In Indonesia, a high rate of breast cancer, especially in Kediri, makes breast cancer the number one position of cancer in women, followed by cervical cancer. Based on research by Harrianto et al. at Dr. Cipto Mangunkusumo Hospital in the Journal of Public Health 8 (2) (2013) 121-126, breast cancer risk factors include a family history of breast cancer patients (15.79%), early menarche (8.77%), nullipara (7.02 %), and long-term use of pills containing estrogen (42.11%). In addition, there are also incidences of breast cancer, namely late menopause, history of breastfeeding, and obesity. From the description above, the purpose of this study is to determine and analyze the risk factors for breast cancer based on a case-control analysis in women at Gambiran Hospital, Kediri. This study uses data collection sheets and field studies, then processed for hypothesis testing so that the objectives of this research can be carried out. This study indicates a significant relationship between the risk factors for a breast cancer history with a p-value of 0.0000 OR 9.837. For women who have families with cancer should be aware of the onset of breast cancer. If they have reached puberty, it is recommended for early detection (screening test) through breast self-examination (BSE), IVA method, and mammography testing.
Systematic Review: Tele-Nursing a Universal Access to Care for Oncology Patients
Authors: Osorio-Calle Yuli Pilar , SebastiÃ¡n-Aquino Katterin Joely , Meneses -La-Riva MÃ³nica Elisa
Published: December 2021

Telenursing is a way of caring for and educating oncology patients to promote self-care management at home. The objective of the study was to analyze the scientific evidence on telenursing in the care of oncology patients. This was a systematic and descriptive review in Spanish, Portuguese and English which was available in 3 databases: BMC, Pubmed and Scielo. The articles were selected in English, Spanish and Portuguese with data from 2010-2020. It was found that tele-nursing, a new form of access to the care service provided by nursing professionals to patients with oncology treatment, including technological tools allow a direct and timely relationship to respond to the detection of adverse events after chemotherapy, promote self-care and control and monitor the patient's health status at home. Conclusions: There is a need to use tele-nursing as an opportunity to care for the patient at home through virtual means by providing relevant information to promote self-care and quality of life.
Role of Capital Budgeting Techniques for Investment Decision Making: An Empirical Study of Public and Private Sector Companies in Pakistan
Authors: Ahmad Nisar , Abid Sheikh Khurram , Maqbool Samia
Published: December 2021

Purpose: Regardless matter whether it is a commercial or public enterprise, every business would have a capital budgeting procedure in residence. The supply of Public goods is the major force on Public sector institutions, and one means to do this is complete the execution of huge progress schemes. With the current state of affairs in Pakistan, major cost and time overruns have occurred on Public sector setup ventures. One of the most likely reasons of cost overruns is a lack of or insufficient cost and benefit ventures, as well as general venture management since the documentation period through the stage after installation period. This study used capital budgeting decision-making methodologies to assess Pakistan's present technological ambitions. Design/Methodology/Approach: In Pakistan, one of the top corporations did a postal survey and a cross-sectional data analysis. Although empirical data suggests a shift toward genuine conceptions and discounted cash flow (DCF) approaches, corporations still fall short of the fundamental needs. Most methodologies are used, including inner proportion of return, net present value (NPV) and payback method (PBM).

Findings: The majority of corporations calculate risk adjusted cash flow, but only a small fraction of firms/businesses use the most modern risk assessment tools.

Implications/Originality/Value: In comparison to other industrialized nations, the utilization of the discounted cash flow (DCF) ratio is still quite low.
A Strategic Vision for Combating Cyberterrorism
Authors: Alsubaie Mathkar
Published: December 2021

Cyberterrorism has become a well-known cybersecurity subject in today's digital world. The spread of cybercrimes calls for disseminating ethical values and peace between countries and individuals. Because of this phenomenon's danger to society, this study sought to lay down directives for security strategies to confront cyberterrorism. Hence, the study's main research problem revolves around highlighting the role of security authorities in addressing cyberterrorism according to the specialists in information technology (IT) centers in Saudi universities in Riyadh. Hence, a descriptive analysis method was adopted as a research methodology. We distributed questionnaires as a study tool to 150 specialists in IT centers in Saudi universities in Riyadh. The study yielded different views regarding the types and ways of cyberterrorism committed through the internet. Results showed the respondents' opinions regarding the essential types of cyberterrorism. Moreover, they emphasize the need to raise awareness in dealing with cyberterrorism by enforcing cybersecurity with the most prominent means and procedures that the authorities are responsible for. The most critical recommendations are: (1) the need to provide the employees with the technical skills to know how to deal with any potential security breach, (2) the need to provide specialized training courses in protection methods for workers, and (3) the need to develop the means of security and legal protection through developing e-government security agreements.
Pembelajaran Ekonomi Pada Masa Pandemi Covid-19
Authors: Saputra Maskhur Dwi
Published: December 2021

This study seeks to find out how economics teachers carry out online learning during the COVID-19 pandemic. This research method uses a qualitative descriptive type, while data collected using interviews with several economics teachers in the Surakarta senior high schools using WhatsApp. The data were collected using purposive and snowball sampling. The results showed that the economics teachers prepared learning instruments at the beginning of the semester. However, the instruments were only the edited instruments from the previous semester. The economics teachers only adjusted them. The instruments made were only as administrative requirements for reports to the local education office. The instruments were not implemented during the learning process. Economics teachers used several media to connect with their students such as WhatsApp Group, Google Classroom, Google Meet, and YouTube. For learning assessment, they used Google Form, Quizzzz, Quipper School, Mentimeter, Kahoot, and the school's e-learning software.
Presentación Vol. 18 - Núm. 2
Authors: Gutiérrez Hidalgo Fernando
Published: December 2021

Presentación del editor
origins of the teaching accounting in russian universities
Authors: Nazarov Dmitry , Sidorova Marina
Published: December 2021

The authors of the paper explore the life and professional activity of Stepan Mikhailovich Usov (1797-1859), as well as his views on the theory and practical implementation of new accounting techniques in agriculture. Usov was a talented researcher, an expert in agricultural sciences, political economy, history, and the publisher and editor of a number of Russian magazines. He worked hard all his life to disseminate knowledge aboutprogressive technologies of agronomy and farm bookkeeping. Usov became one of the first lecturers in accounting, which he taught at St. Petersburg University in 1836 and this is in the focus of the study. Based on the Actor–network theory of Bruno Latour (ANT), the authors contribute to the previous literature within biographical studies and accounting education by identifying Usov’s role in the development of Russian accounting as a mediator inthe network of educational institutions, which transformed accounting into a university discipline.
Sistema contable y rendición, revisión, cierre y definición de cuentas en la Hacienda Municipal de Valencia. Los Capitols del Quitament de 1559-1571
Authors: Mayordomo García-Chicote Francisco
Published: December 2021

En este trabajo se analiza la normativa que modernizó la gestión contable de la hacienda municipal de Valencia en la segunda mitad del siglo XVI. Dicha normativa era conocida como Capitols del Quitament, en nuestro caso los vigentes entre 1559 y 1571. Estos eran unos elementales presupuestos cuyo objetivo era mantener a la ciudad descargada de obligaciones financieras, con la supervisión de los Catorze del Quitament. La modernización contable se consiguió implantando un nuevo sistema basado en la aplicación de la partida doble en los recién creados Mayor y Manual de la Negociació, similares a los del Banco Público Municipal desde 1519, así como la rendición de cuentas al Racional y la revisión continua del Mayor y de los ocho libros auxiliares de la hacienda local, a cargo del Racional, con la colaboración de los Catorze del Quitament; y la definición de los ocho altos cargos de dicha hacienda.
emprendimiento ilustrado institucional en el virreinato de Nueva Granada 1767-1789. La administración de las temporalidades y la reforma universitaria. Tesis de la autora Carolina Tovar Torres
Authors: Gutiérrez Hidalgo Fernando
Published: December 2021

Tesis de la autora Carolina Tovar Torres, dirigida por Fernando Gutiérrez Hidalgo y Juan Baños Sánchez-Matamoros (Universidad Pablo de Olavide de Sevilla, España).La investigación da a conocer el papel de la contabilidad en los cambios que se dieron en el último tercio del siglo XVIII en el Virreinato de Nueva Granada (hoy Colombia) a raíz de la expulsión de la Compañía de Jesús y como influyeron en el Virreinato de tal manera que se configuró un nuevo orden económico-contable. Modelo que condujo a la reforma universitaria y a la institucionalización de nuevas prácticas de rendición de cuentas en el ámbito universitario.
Crónica del Congreso EAA 1992 que dio inicio al proceso de internacionalización de la comunidad académica contable española
Authors: Cañibano Leandro
Published: December 2021

El Congreso de la European Accounting Association (EAA) en Madrid 1992, supuso el inicio del proceso de internacionalización de la comunidad académica contable española. Partiendo de Congresos EAA anteriores se glosa el de 1992, su programa científico y sus efectos sobre la participación española en las relaciones internacionales y redes de investigación. Se mencionan la creación del Center for Research in European Accounting (CREA) y de European Accounng Review (EAR), así como a los proyectos de investigación con financiación de la Comisión Europea (CE), sobre reporte financiero y análisis de intangibles, durante el período 1993-2010. Se alude a la internacionalización de la REFC/SJFA y a los simposios y ciclos de conferencias internacionales que vienen celebrándose anualmente desde 2005 hasta el momento presente.
Noticias y próximos congresos
Authors: Computis De
Published: December 2021

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AS APARÊNCIAS ENGANAM OU SOBRE DIALOGISMO E REDES SOCIAIS
Authors: Pucci Penteado de Faria e Silva Adriana
Published: December 2021

Neste artigo, o objetivo é mostrar o diálogo com um corpus de análise construído a partir de uma experiência de interação em redes sociais. A base teórica e epistemológica emerge dos escritos de Bakhtin e dos demais pesquisadores do Círculo, em diálogo com pesquisas feitas por Amorim (2000, 2007, 2015) sobre formas de saber e de conhecimento e sua relação com interações discursivas de diferentes naturezas. Apresenta-se uma reprodução de frames da postagem no Instagram que gerou as interações em análise e mostra-se uma seleção de repostas a um comentário crítico. Pela análise de alguns aspectos linguísticos e discursivos dessas interações, flagra-se um discurso que contrapõe o Instagram ao Facebook, posicionando essas redes de acordo com os usuários que nelas deveriam circular. Conclui-se que há hábitos monologizantes exercendo certas coerções nas redes, mas aponta-se que, nas interações, existe a possibilidade de refração desses hábitos.