bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the Needs and Lived Experiences of Racial and Ethnic Minority Domestic Violence Survivors Through Community-Based Participatory Research: A Systematic Review
Authors: Ragavan Maya I. , Thomas Kristie A. , Fulambarker Anjali , Zaricor Jill , Goodman Lisa A. , Bair-Merritt Megan H.
Published: December 2018

Community-based participatory research (CBPR) is a methodological approach where community–academic teams build equitable relationships throughout the research process. In the domestic violence (DV) field, CBPR may be particularly important when conducting research with racial and ethnic minority DV survivors, as this group faces concurrent oppressions that inform their lived experiences. To our knowledge, no systematic review has synthesized articles using a CBPR approach to explore the needs and lived experiences of racial and ethnic minority DV survivors. Using PRISMA guidelines, we conducted a systematic review of the literature, retrieving articles that used a CBPR approach to understand the needs and/or lived experiences of female racial and ethnic minority DV survivors residing in the United States. Articles were identified from peer-reviewed databases, bibliographies, and experts. Thirteen of the 185 articles assessed for eligibility were included. Articles focused on a variety of racial and ethnic minority groups, the majority identifying as African American or Latina. Collaboration occurred in multiple ways, primarily through equitable decision-making and building team members’ strengths. Several needs and lived experiences emerged including gender identity and patriarchal attitudes, racism and discrimination, the immigrant experience informing DV, poverty, shame and stigma, and the need for social support. This is the first systematic review of articles using a CBPR approach to explore the needs and lived experiences of racial and ethnic minority survivors. Implications include promoting community-based dissemination, conducting quantitative studies with larger sample sizes of DV survivors, and encouraging culturally specific services that address DV survivors’ intersectional needs.
Meta-analysis of Individual Patient Data After Kissing Stent Treatment for Aortoiliac Occlusive Disease
Authors: Groot Jebbink Erik , Holewijn Suzanne , Versluis Michel , Grimme Frederike , Hinnen Jan Willem , Sixt Sebastian , Angle John F. , Dorigo Walter , Reijnen Michel M. P. J.
Published: November 2018

Purpose: To evaluate short- and long-term technical and clinical outcomes after kissing stent treatment of aortoiliac occlusive disease (AIOD) based on an individual participant data (IPD) meta-analysis. Materials and Methods: A search of the Scopus database identified 156 articles on KS treatment of AIOD; of these 22 met the inclusion criteria. Authors of 19 articles with contact information were approached to join an IPD consortium. Eight author groups responded and 5 provided anonymized data for merging into an IPD database. The number of included procedures was equal before and after 2005. The primary study outcome was the cumulative patency at 24 months. Secondary outcomes were patency at up to 60 months, complications, and changes in Rutherford category and ankle-brachial index. The predictive value of stent protrusion length, pre-/postdilation, stent type, and patient demographics on primary patency were examined with Cox proportional hazard modeling; outcomes are reported as the hazard ratio (HR). The Kaplan-Meier method was employed to estimate patency rates. Results: In total, 605 (40.9%) of 1480 patients presented in the literature were included in the IPD analysis. The indication for intervention was intermittent claudication in 84.2% and critical limb ischemia in 15.8%. Lesions were classified as TransAtlantic Inter-Society Consensus (TASC) A or B in 52.8% and TASC C and D in 47.2%. The overall primary patency estimate was 81% at 24 months. Primary patency significantly increased after 2005 (p=0.005). Cox regression analysis revealed only age as a significant predictor of sustained primary patency (HR 0.60, p<0.005). Any previous endovascular intervention (HR 2.52, p=0.02) was the main predictor for loss of secondary patency; history of cardiovascular disease (HR 0.27, p=0.04) was the main predictor of sustained secondary patency. Conclusion: The kissing stent technique has a good safety profile and acceptable patency rates up to 2 years, even in TASC C and D lesions, supporting an endovascular-first approach for AIOD.
Potential Impact of Phellinus linteus on Adherence to Adjuvant Treatment After Curative Resection of Pancreatic Ductal Adenocarcinoma: Outcomes of a Propensity Score–Matched Analysis
Authors: Lee Sung Hwan , Hwang Ho Kyoung , Kang Chang Moo , Lee Woo Jung
Published: December 2018

Background: Surgical resection followed by adjuvant chemotherapy is the only therapeutic option in pancreatic cancer. However, there is limited research evaluating methods of improving adherence to adjuvant treatment after curative resection. Methods: From January 1995 to December 2014, 323 patients with pancreatic cancer who underwent pancreatectomy at the Severance Hospital were enrolled in this study. We retrospectively analyzed clinicopathologic factors with propensity score matching method. Results: The final study population was 217, after excluding patients undergoing neoadjuvant treatment or palliative resection, those who died within 30 days after operation, and those lost to follow-up after discharge. Among them, 161 received adjuvant treatment after curative resection. Cox’s proportional hazard models revealed that nodal metastasis, perioperative transfusion, and completion of adjuvant treatment were significantly correlated with cancer recurrence and cancer-related death ( P < .05). Phellinus linteus (PL) medication was the only significant predictor for completion of adjuvant treatment after curative resection in logistic regression analysis ( P = .039). Disease-free and overall survival of the PL medication group were significantly higher than the no PL medication group ( P < .05). Conclusions: PL medication potentially contributed to long-term oncologic outcomes by increasing patients’ adherence to postoperative adjuvant chemotherapy, which resulted from PL medication associated with low toxicity of chemotherapy.
Meta-analysis Comparison of Bilateral Axillo-Breast Approach Robotic Thyroidectomy and Conventional Thyroidectomy
Authors: Shan Liqun , Liu Jianing
Published: December 2018

Objective. Despite gaining popularity, bilateral axillo-breast approach robotic thyroidectomy (BABA RT) remains controversial. We performed a meta-analysis to evaluate the safety and effectiveness of BABA RT compared with open thyroidectomy (OT) in thyroid disease. Methods. A literature search was conducted using various databases, including PubMed, Web of Science, and Cochrane Library, up to February 2018. Outcomes of interest included patient characteristics, surgical outcomes, adverse events, complications, and surgical completeness. Results. A total of 11 publications including 2733 patients (1070 in the BABA RT and 1663 in the open group) were finally selected for the meta-analysis. BABA RT was associated with an equivalent complication rate, including transient and permanent hypocalcemia, transient and permanent recurrent laryngeal nerve palsy, bleeding, chyle leakage, and seroma, as well as surgical outcomes including tumor size, length of hospital stay, total drain amount, and pain score. BABA RT was also associated with an equivalent surgical completeness, including total dose of radioactive iodine, proportion of stimulated thyroglobulin (sTg) <1.0 ng/mL, and level of sTg. Moreover, BABA RT involved longer operative times (weighted mean difference [WMD] = 110.13; P < .00001), smaller number of retrieved lymph nodes(WMD = −1.26, P = .003), and more cost (WMD = 5811.18; P < .00001) compared with OT. Conclusions. BABA RT is safe and feasible and provides similar perioperative outcomes and complications when compared with OT. However, BABA RT was associated with longer operating time, fewer retrieved lymph nodes, and more cost. Randomized clinical trials with large samples and longer follow-up data are needed to more rigorously examine this effect.
Requirements for Transparency and Communicability of Regulatory Science
Authors: Moghissi A. Alan , Calderone Richard A. , Estupigan Camille , Koch Rae , Manfredi Kelsey , Vanderdys Vanessa
Published: December 2018

This article presents the results of a study attempting to provide examples that implement transparency and communicability elements of Ethical Rules Principle of Best Available Regulatory Science (BARS) and Metrics for Evaluation of Regulatory Science Claims (MERSC). It starts with an overview of regulatory science and briefly summarizes principles of BARS and key pillars of MERSC. Subsequently, the BARS/MERSC system is used to evaluate the linear nonthreshold (LNT) process used in cancer assessments and the similar process used for evaluating in particulate matter (PM) exposure. The study identifies 3 parts in dose–response curves, where the first part is reproducible science and the second part includes uncertainties and often requires the application of precautionary principle. The primary reason for disagreements on LNT and PM is a lack of recognition that the third part is based on desire of regulators to be protective, a policy decision process. Two PM epidemiological examples are included in this study to demonstrate the point. The regulatory process would benefit from recognizing the distinction between science and policy and excluding policy from regulatory science. Furthermore, the society would greatly benefit from increased transparency in the regulatory process and compliance with the Jeffersonian communication principle
Youth Sports Specialization: Does Practice Make Perfect?
Authors: Matzkin Elizabeth , Garvey Kirsten
Published: December 2018

In the United States, there has been a steady increase in sports participation across all age groups. An estimated 27 million youths between the ages of 6 and 18 years participate in team sports, and 60 million participate in some form of organized athletics. While there are great benefits from sports participation, early single sport specialization carries an increased risk of overuse injuries and burnout. Specialization has become increasingly popular among parents and coaches due to the common belief that it is the best way to develop an elite athlete. However, for most sports, there is no evidence that specialization before puberty is necessary to achieve elite status and in fact, there is evidence to the contrary. A recent American Orthopaedic Society for Sports Medicine (AOSSM) consensus statement has highlighted the negative side effects of early sports specialization; these include increased risk for overuse injury and burnout. School nurses are well-positioned to affect this issue through providing education and raising awareness of the potential detrimental consequences associated with youth sport specialization.
Patency of anterior choroidal artery after flow diverter deployment with assessment of magnetic resonance imaging follow-up
Authors: Fujii Takashi , Oishi Hidenori , Teranishi Kohsuke , Yatomi Kenji , Yamamoto Munetaka , Arai Hajime
Published: December 2018

Purpose

We aimed to analyse the patency rate of the anterior choroidal artery, and presented imaging and neurological findings, after deployment of a flow diverter in the anterior choroidal artery in the treatment of patients with intracranial aneurysms.

Methods

Among the 139 patients who underwent a flow diverter deployment from December 2012 to September 2017 in our hospital, there were 21 patients (15.1%) for whom their anterior choroidal artery was covered for the procedure with a flow diverter. The patients' age, sex, size of aneurysm and the presence or absence of an anterior choroidal artery occlusion, neurological findings and postoperative infarction in the anterior choroidal artery region were analysed retrospectively.

Results

The mean age of the six male and 15 female patients was 61.5 years (range 32–77 years). The mean maximal diameter of the aneurysms was 16.4 mm (range 10.0–29.4 mm). The anterior choroidal artery was patent in all 21 patients; however, a haemodynamic alteration in the anterior choroidal artery was detected in one patient. Postoperatively, hemiparesis was observed in two patients (9.5%) and a visual field defect in one patient (4.8%), both of which were the symptoms of infarction of the cortical branch of the middle cerebral artery or retinal artery ischaemia. However, no patients had symptoms due to ischaemia of the anterior choroidal artery confirmed with magnetic resonance imaging.

Conclusions

In all patients who underwent flow diverter deployment, the anterior choroidal artery was patent and no ischaemia was detected in the imaging or evidenced by neurological findings. Therefore, flow diverter deployment in the anterior choroidal artery was considered to be a safe procedure.
Economic Evaluation of an Integrated Health and Social Care Program for Heart Failure Through 2 Different Modeling Techniques
Authors: Larrañaga Igor , Stafylas Panos , Fullaondo Ane , Apuzzo Gian Matteo , Mar Javier
Published: December 2018

Introduction:

An integrated health and social care program for patients with heart failure (HF) was implemented at the Friuli-Venezia Giulia deployment site as part of the SmartCare European project. The objective of this study was to validate 2 different decision modeling techniques used to perform the economic evaluation.

Methods:

Data were collected during the SmartCare project which enrolled 108 patients with HF and followed for more than 6 months. The techniques used were Markov and discrete event simulation models. In both cases, a cost-effectiveness analysis and a budget impact analysis were carried out. The former was used to assign priority to the intervention and the latter to assess its sustainability. Analyses were conducted from the perspective of the Regional Health Authority.

Results:

Results were similar with both types of model. Cost-effectiveness analysis found no significant differences in quality of life, but the intervention generated significant cost savings, becoming the dominant option. Data extrapolation showed no benefits in terms of mortality or hospital admissions, but budget impact analysis also predicted annual savings, as a significant number of in-hospital days were avoided. In budget analysis, both models predicted early, increasing and cumulative annual savings.

Discussion:

The integrated program was dominant as it provided better outcomes and lower total costs, and thus, decision-makers should prioritize it. Besides, the work demonstrates the capacity of decision modeling to become a complementary tool in managing integrated health and social care models.
The Legacy of Mary Bird
Authors: Khamushi Musa
Published: December 2018

English missionaries with the Church Missionary Society (CMS) began their work in Persia in 1869. In 1891 the CMS sent Mary Bird to Persia to evangelize Muslim women. In this article I consider Bird’s activities among Muslim women of Isfahan. Her work included establishing dispensaries and offering medical services to women and children. During the first phase of her time in Persia (1891–97), a small number of Muslim women and girls converted to Christianity.
Ravulizumab (ALXN1210) vs eculizumab in adult patients with PNH naive to complement inhibitors: the 301 study
Authors: Lee Jong Wook , Sicre de Fontbrune Flore , Wong Lee Lee Lily , Pessoa Viviani , Gualandro Sandra , Füreder Wolfgang , Ptushkin Vadim , Rottinghaus Scott T. , Volles Lori , Shafner Lori , Aguzzi Rasha , Pradhan Rajendra , Schrezenmeier Hubert , Hill Anita
Published: December 2018

Ravulizumab (ALXN1210), a new complement C5 inhibitor, provides immediate, complete, and sustained C5 inhibition. This phase 3, open-label study assessed the noninferiority of ravulizumab to eculizumab in complement inhibitor–naive adults with paroxysmal nocturnal hemoglobinuria (PNH). Patients with lactate dehydrogenase (LDH) ≥1.5 times the upper limit of normal and at least 1 PNH symptom were randomized 1:1 to receive ravulizumab or eculizumab for 183 days (N = 246). Coprimary efficacy end points were proportion of patients remaining transfusion-free and LDH normalization. Secondary end points were percent change from baseline in LDH, change from baseline in Functional Assessment of Chronic Illness Therapy (FACIT)–Fatigue score, proportion of patients with breakthrough hemolysis, stabilized hemoglobin, and change in serum free C5. Ravulizumab was noninferior to eculizumab for both coprimary and all key secondary end points (Pinf < .0001): transfusion avoidance (73.6% vs 66.1%; difference of 6.8% [95% confidence interval (CI), −4.66, 18.14]), LDH normalization (53.6% vs 49.4%; odds ratio, 1.19 [0.80, 1.77]), percent reduction in LDH (−76.8% vs −76.0%; difference [95% CI], −0.83% [−5.21, 3.56]), change in FACIT-Fatigue score (7.07 vs 6.40; difference [95% CI], 0.67 [−1.21, 2.55]), breakthrough hemolysis (4.0% vs 10.7%; difference [95% CI], −6.7% [−14.21, 0.18]), and stabilized hemoglobin (68.0% vs 64.5%; difference [95% CI], 2.9 [−8.80, 14.64]). The safety and tolerability of ravulizumab and eculizumab were similar; no meningococcal infections occurred. In conclusion, ravulizumab given every 8 weeks achieved noninferiority compared with eculizumab given every 2 weeks for all efficacy end points, with a similar safety profile. This trial was registered at www.clinicaltrials.gov as #NCT02946463.
Infidel America: Puritan Legacy and Antebellum Religious Persecution in Frederick Douglass’s Transatlantic Speeches, 1841–49
Authors: Grace Daniel
Published: November 2018

This essay examines Frederick Douglass’s oratory of the 1840s, when religious appeals drove his abolitionist rhetoric. In addressing the lack of critical attention paid to his early oratory and evangelism, the essay argues that these speeches, which he delivered to audiences in the US North and Europe, offer an incisive transatlantic critique of the religious roots of American exceptionalism by attacking American Protestantism and the growing mythology of the nation’s Puritan origins. Douglass’s early speeches undercut the celebration of Puritan ancestry by Daniel Webster, George Bancroft, and others; provide a thick description of US antebellum religious persecution in both the North and South; and deploy missionary rhetoric to call on European Protestant churches to remake their US counterparts. For 1840s Douglass, slavery in the United States was not a result of the country failing to live up to its founding republican principles, an argument he would make in subsequent decades. Rather, the more radical and zealous appraisal of the country he offered at that time was that the country’s founding reliance on slavery and servitude meant that it was, at core, an apostate nation in need of Christian conversion.
Feminisms in African Hip Hop
Authors: Clark Msia Kibona
Published: November 2018

Women hip hop artists in Africa have created spaces for themselves within hip hop’s (hyper)masculine culture. They have created these spaces in order to craft their own narratives around gender and sexuality and to challenge existing narratives. This research uses African feminism as a broad lens through which to examine how these women artists present challenges to patriarchy, gender norms, and the politics of respectability that may or may not align with African feminist ideologies. In addition to resistance, this research examines how these artists use their art to construct their own dynamic and multidimensional representations in ways that find parallels within African feminisms. In this study, more than three hundred songs produced by women hip hop artists were surveyed. The study revealed diverse expressions of feminist identities, implicit and explicit rejections of patriarchy, and expressions of sexuality that included agency and nonconformity.
A SUMOylation dependent switch of Rab7 governs intracellular life and pathogenesis of Salmonella Typhimurium
Authors: Mohapatra Gayatree , Gaur Preksha , Prabhakar M. , Singh Mukesh , Rana Sarika , Singh Shivendra , Kaur Navneet , Verma Smriti , Krishna V. , Singh Nirpendra , Srikanth C. V.
Published: December 2018

Salmonella Typhimurium (ST) is an intracellular pathogen that causes gastroenteritis in humans. Aided by a battery of effector proteins, ST resides intracellularly in a specialized vesicle, called Salmonella-containing vacuole (SCV) that utilizes the host endocytic vesicular-transport pathway (VTP). Here we probed the possible role of SUMOylation, a post-translation modification pathway, in SCV biology. Proteome analysis by complex mass-spectrometry (MS/MS) revealed a dramatically altered SUMO-proteome (SUMOylome) in ST infected cells. Rab7, a component of VTP, was key among several crucial proteins identified in our study. Detailed MS/MS along with in vitro SUMOylation assays and structural docking analysis revealed SUMOylation of Rab7 specifically at Lysine-175. A SUMOylation deficient Rab7 mutant (Rab7K175R) displayed longer half-life, was beneficial to SCV dynamics and functionally blemished. Collectively the data revealed that Rab7 SUMOylation blockade by ST ensures availability of long-lived but functionally compromised Rab7 which was beneficial to the pathogen. Overall this SUMOylation dependent switch of Rab7 controlled by ST is an unexpected mode of VTP pathway regulation, and unveils mechanism of broad interest well beyond Salmonella-host crosstalk.
Editorial
Authors: Καλογιαννάκης Μιχαήλ , Καλκάνης Γεώργιος
Published: December 2018

Σχεδιασμός και αξιοποίηση των ψηφιακών σεναρίων για τη διδασκαλία των Φυσικών Επιστημών - Εισαγωγή ειδικού τεύχους
Διαδραστικό Ψηφιακό Διδακτικό Σενάριο Αξιοποίησης και Δημιουργίας Βίντεο στη Διδασκαλία των Θετικών Επιστημών
Authors: Παπαδημητρίου Σοφία
Published: December 2018

Στο άρθρο παρουσιάζεται το διαδραστικό ψηφιακό διδακτικό σενάριο στην Πλατφόρμα «Αίσωπος» με τίτλο «Δημιουργία βίντεο στο School-Lab», το οποίο προτείνει μεθόδους αξιοποίησης και δημιουργίας βίντεο στο σχολείο στοχεύοντας στην προσέγγιση των Θετικών Επιστημών με ελκυστικό τρόπο. Το σενάριο αποσκοπεί να λειτουργήσει ως «καθοδηγούμενη διδακτική συνδιάλεξη» προς τους εκπαιδευτικούς που επιθυμούν να υποστηρίξουν τον σχεδιασμό και την ανάπτυξη μαθητικών βίντεο στην εκπαιδευτική δράση «School-Lab» σε ένα πλαίσιο συμπληρωματικής σχολικής εξ αποστάσεως εκπαίδευσης. Η υλοποίηση του ψηφιακού σεναρίου υποστηρίζει το έργο των εκπαιδευτικών να δημιουργήσουν ένα αυθεντικό περιβάλλον μάθησης, το οποίο παρέχει τα ερεθίσματα στους μαθητές για προσέγγιση και κατανόηση γνωστικών αντικείμενων των Θετικών Επιστημών και επιπλέον προσφέρει συνθήκες συνεργατικής δημιουργικότητας και καλλιέργειας των δεξιοτήτων του 21ου αιώνα.
Διδασκαλία της έννοιας της ύλης στο δημοτικό σχολείο με αξιοποίηση του εκπαιδευτικού προτύπου του μικρόκοσμου
Authors: Γκικοπούλου Ουρανία
Published: December 2018

Πολλές έρευνες έχουν δείξει ότι οι μαθητές δυσκολεύονται να κατανοήσουν την έννοια της ύλης και τις φυσικές μεταβολές της. Θεωρούμε ότι οι δυσκολίες αυτές οφείλονται στο γεγονός ότι έχουν διαμορφώσει αρχικές ερμηνείες για την ύλη που διαφέρουν από τις αντίστοιχες επιστημονικές. Το πρότυπο του μικρόκοσμου είναι ένα πολύτιμο εργαλείο για την κατανόηση των εννοιών αυτών και την ερμηνεία των μακροσκοπικών φαινομένων. Στο παρόν σενάριο εφαρμόζουμε μια διδακτική παρέμβαση που σκοπό έχει να βοηθήσει τους μαθητές να μεταβούν από τις βασιζόμενες στις αισθήσεις αντιλήψεις τους για την ύλη στις πιο αφηρημένες έννοιες της επιστημονικής θεωρίας, αξιοποιώντας μια σειρά από πόρους, συμπεριλαμβανομένου και του εκπαιδευτικού προτύπου του μικροκόσμου. Βασικό στοιχείο του σεναρίου για μαθητές της Ε’ Δημοτικού είναι ότι λαμβάνει υπόψη του τις αντιλήψεις των μαθητών για την ύλη, ενώ η εισαγωγή της σωματιδιακής θεωρίας γίνεται με τη βοήθεια προσομοιώσεων του μοντέλου του μικρόκοσμου. Επίσης, αξιοποιούνται όλοι οι διαθέσιμοι υλικοί και ψηφιακοί πόροι συνθέτοντας ένα εκπαιδευτικό ψηφιακό σενάριο που βασίζεται στην επιστημονική/εκπαιδευτική μεθοδολογία με διερεύνηση. Η εφαρμογή του σεναρίου έδειξε ότι επηρέασε θετικά τις αντιλήψεις των μαθητών για την ύλη, υποστηρίζοντας και την άποψη ότι η μικροσκοπική προσέγγιση της ύλης τους βοηθά να προσεγγίσουν καλύτερα τις μακροσκοπικές έννοιες.
Διδασκαλία της Διάθλασης του Φωτός με τη Χρήση της Εφαρμογής Δισδιάστατης Απεικόνισης Algodoo
Authors: Βλιώρα Ελένη , Μουζάκης Χαράλαμπος , Καλογιαννάκης Μιχάλης
Published: December 2018

Η αξιοποίηση διδακτικών σεναρίων αναγνωρίζεται ως καινοτόμα παιδαγωγική πρακτική στην εκπαιδευτική διαδικασία καθώς συνδέεται με την προώθηση μαθητοκεντρικών εκπαιδευτικών προσεγγίσεων υπό το πρίσμα των αρχών της εποικοδομητικής μάθησης. Η ένταξη των ΤΠΕ στο πλαίσιο παιδαγωγικά τεκμηριωμένων διδακτικών και μαθησιακών δραστηριοτήτων προσφέρει ευκαιρίες ενεργούς εμπλοκής των μαθητών σε διαδικασίες διερευνητικής και συνεργατικής μάθησης και υποστηρίζει διεργασίες που οδηγούν στην εννοιολογική κατανόηση κατά τη διδασκαλία των Φυσικών Επιστημών. Στην παρούσα εργασία περιγράφεται ένα διδακτικό σενάριο το οποίο αξιοποιεί το λογισμικό δισδιάστατης διαδραστικής σχεδίασης Algodoo για την υποστήριξη της διδασκαλίας της ενότητας «Φως» του μαθήματος «Ερευνώ τον Φυσικό Κόσμο» της Στ’ Τάξης του Δημοτικού Σχολείου. Στο πλαίσιο του προτεινόμενου διδακτικού σεναρίου το λογισμικό δισδιάστατης διαδραστικής σχεδίασης Alogdoo εντάσσεται σε δραστηριότητες καθοδηγούμενης διερεύνησης οι οποίες αποσκοπούν στο να προσφέρουν στους μαθητές δυναμικές οπτικές αναπαραστάσεις που προσελκύουν το ενδιαφέρον τους και τους επιτρέπουν να κάνουν προβλέψεις, υποθέσεις και ερμηνείες για το φαινόμενο της διάθλασης του φωτός.
Σενάρια περιβαλλοντικών εκπαιδευτικών δραστηριοτήτων με την αξιοποίηση του Διαδικτύου των Αντικειμένων
Authors: Τζιωρτζιώτη Χρυσάνθη , Μαυρομμάτη Ειρήνη , Μυλωνάς Γεώργιος , Χατζηγιαννάκης Ιωάννης
Published: December 2018

Η ευαισθητοποίηση των νέων και η αλλαγή των συνηθειών τους όσον αφορά στην προστασία του περιβάλλοντος και την εξοικονόμηση ενέργειας, θα είναι καθοριστικής σημασίας για την διατήρηση ενός βιώσιμου πλανήτη στο εγγύς μέλλον. Σε αυτό το πλαίσιο, η αντιμετώπιση της κλιματικής αλλαγής απαιτεί αρχικά την ενημέρωση και κατόπιν την αλλαγή νοοτροπίας και εφαρμογή συμπεριφορών φιλικότερων προς το περιβάλλον. Σε αυτό το κείμενο, παρουσιάζουμε μερικές εκπαιδευτικές πρακτικές STEM που αξιοποιούν συστήματα Διαδικτύου των Αντικειμένων με αισθητήρες (Internet of Things, IoT), σε συνδυασμό με κατάλληλα σχεδιασμένες εκπαιδευτικές δραστηριότητες διερευνητικής μάθησης. Η ενίσχυση της εκπαιδευτικής κοινότητας στην περιβαλλοντική εκπαίδευση των νέων έχει πολλαπλασιαστικό αποτέλεσμα, καθώς η υιοθέτηση ενεργειακά αποδοτικών συνηθειών επηρεάζει και το άμεσο οικογενειακό τους περιβάλλον. Ως ένα τέτοιο παράδειγμα, η πλατφόρμα του έργου GAIA αξιοποιεί πραγματικά δεδομένα από σχολικά κτίρια, και μπορεί να χρησιμοποιηθεί ως βάση για τη σχεδίαση εκπαιδευτικών δραστηριοτήτων STEM, αντλώντας δεδομένα από διάφορα περιβάλλοντα. Επιπλέον, προτείνεται η χρήση αισθητήρων για τη μέτρηση βασικών ωκεανογραφικών παραμέτρων όπως η θερμοκρασία, η αλατότητα, το διαλυμένο οξυγόνο, η αλκαλικότητα και η θολερότητα σε παράκτια περιβάλλοντα, η οποία δεν έχει εξεταστεί  στο παρελθόν, ως ένα επόμενο βήμα για το σχεδιασμό εκπαιδευτικών σεναρίων αυτού του τύπου.
Lead toxicosis in cats and dogs
Authors: Bates Nicola
Published: December 2018

Lead has no biological role but is ubiquitous in the environment. The incidence of lead poisoning in both humans and animals has declined in the past few decades; however, there are still potential sources in and around the home, including lead paint and lead-containing materials such as curtain weights and lead flashing. Signs of lead poisoning mainly involve the gastrointestinal and neurological systems, and a typical presentation is several days’ history of gastrointestinal signs (anorexia, vomiting) followed by neurological signs such as seizures. Behavioural changes may also be reported. Diagnosis of lead poisoning can be difficult, since a blood lead concentration is not immediately available and does not correlate well with severity of poisoning. Diagnosis is therefore usually based on clinical signs, laboratory findings and client history. Treatment is aimed at identifying the source of poisoning, reducing/eliminating exposure, management of signs, and potential use of a lead chelating agent. Prognosis is good with treatment, but more guarded in animals with severe neurological signs.
A difficulty in understanding
Authors: Sobel Daniel
Published: December 2018

Continuing his SecEd series, Daniel Sobel describes a common intervention scenario that he sees in schools and which often goes wrong because we don't spot the student's primary need
Concurrent femoral head reduction and periacetabular osteotomies for the treatment of severe femoral head deformities
Authors: Clohisy J. C. , Pascual-Garrido C. , Duncan S. , Pashos G. , Schoenecker P. L.
Published: November 2018

Aims

The aims of this study were to review the surgical technique for a combined femoral head reduction osteotomy (FHRO) and periacetabular osteotomy (PAO), and to report the short-term clinical and radiological results of a combined FHRO/PAO for the treatment of selected severe femoral head deformities.

Patients and Methods

Between 2011 and 2016, six female patients were treated with a combined FHRO and PAO. The mean patient age was 13.6 years (12.6 to 15.7). Clinical data, including patient demographics and patient-reported outcome scores, were collected prospectively. Radiologicalally, hip morphology was assessed evaluating the Tönnis angle, the lateral centre to edge angle, the medial offset distance, the extrusion index, and the alpha angle.

Results

The mean follow-up was 3.3 years (2 to 4.6). The modified Harris Hip Score improved by 33.0 points from 53.5 preoperatively to 83.4 postoperatively (p = 0.03). The Western Ontario McMasters University Osteoarthritic Index score improved by 30 points from 62 preoperatively to 90 postoperatively (p = 0.029). All radiological parameters showed significant improvement. There were no long-term disabilities and none of the hips required early conversion to total hip arthroplasty.

Conclusion

FHRO combined with a PAO resulted in clinical and radiological improvement at short-term follow-up, suggesting it may serve as an appropriate salvage treatment option for selected young patients with severe symptomatic hip deformities.
Outcome-based commissioning of knee arthroplasty in the NHS
Authors: Middleton R. , Wilson H. A. , Alvand A. , Abram S. G. F. , Bottomley N. , Jackson W. , Price A.
Published: November 2018

Aims

Our unit was identified as a negative outlier in the national patient-reported outcome measures (PROMs) programme, which has significant funding implications. As a centre that carries out a high volume of unicompartmental knee arthroplasty (UKA), our objectives were: 1) to determine whether the PROMs programme included primary UKA when calculating the gain in Oxford Knee Score (OKS); and 2) to determine the impact of excluding primary UKA on calculated OKS gains for primary knee arthroplasty.

Materials and Methods

National PROMs data from England (2012 to 2016) were analyzed. Inclusion of UKA cases in the national PROMs programme was determined using clinical codes. Local OKS gain was calculated for UKA and TKA and compared with the published PROMs results for 2012/13.

Results

Use of the recommended codes for primary UKA excluded 99.6% of UKAs locally and 97% nationally from PROMs programme analysis. Inclusion of primary UKAs in PROMs analysis improved our OKS gain from 15.1 (below average) to 16.3 (above average) for 2012/13 for primary knee arthroplasty.

Conclusion

Exclusion of UKA patients from the PROMs programme is a nationwide issue that potentially introduces bias when comparing OKS gain between centres. Where commissioning decisions are based on routinely collected data, it is imperative that the underlying methodology is appropriate to generate valid results.
Comparison of different final irrigant agitation techniques for the removal of Enterococcus faecalis biofilms from root canals: an in vitro study
Authors: Gunec Gurkan , Haznedaroglu Faruk , Kulekci Guven , Topcuoglu Nursen Bakir , Özcan Mutlu
Published: November 2018

Objective: The aim of this in vitro study was to compare the effectiveness of different final irrigant agitation techniques in the removal of Enterococcus faecalis biofilms from root canals. Material and Methods: In total, the root canals of 85 extracted single-rooted human maxillary incisors teeth were prepared using the Revo-S system to a 40/06 size. The apical foramen of each tooth was sealed by light-cured resin composite material to obstruct bacterial leakage. The specimens were sterilized in an autoclave at 121°C for 15 min and stored until further use. All teeth except five (negative control group) were inoculated with Enterococcus faecalis and incubated in a CO2 chamber at 37°C for 7 days; the trypticase soy broth was changed every 2 days. For the determination of possible biofilm formation, five of the 80 teeth were randomly selected as a positive control group; one tooth of positive control group was analysed for biofilm development by scanning electron microscope (SEM) and these teeth received no final irrigant agitation procedure. Then, the remaining 75 teeth were randomly divided into five test groups (n=15 each) and were sequentially irrigated with 5% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid and 5% NaOCl. Following each irrigant application, different final irrigant agitation techniques were introduced for 60 s (3×20-s sessions). Group 1 received manual–dynamic agitation, group 2 received passive ultrasonic agitation (PUI), group 3 received EndoActivator agitation, group 4 received photon-initiated photoacoustic streaming (PIPS) with the Er:YAG laser and group 5 received conventional syringe irrigation. Colony-forming units (CFUs) were counted in samples from the positive control and test groups. Data were analysed using Kruskal–Wallis and post-hoc Mann–Whitney U multiple comparison tests. Results: E. faecalis elimination was significantly better in the experimental groups than in the positive control groups (p < 0.001). Manual–dynamic agitation and conventional syringe irrigation, with no significant differences between the two groups. Conclusion: Essentially, CFU reduction was significantly greater in the PUI, EndoActivator and PIPS groups than in the manual–dynamic agitation and conventional syringe irrigation groups (p <0.001), with no significant differences among the former three groups.KeywordsEnterococcus faecalis; Irrigant agitation; Irrigant solutions; Photon-initiated photoacoustic streaming; Passive ultrasonic irrigation.
Comparative evaluation of post-operative pain after pulpectomy with k-files, kedo-s files and mtwo files in deciduous molars -a randomized clinical trial
Authors: Nair Manisha , Jeevanandan Ganesh , R Vignesh , EMG Subramanian
Published: November 2018

Objective: Despite the tortuous course of primary root canal system, a paradigm shift occurred from conventional hand files to rotary system, which lead to faster, cost-effective, uniform and predictable fillings. One of the many advantages being, reduction in post-operative pain with the use of rotary system. Many rotary file systems were introduced, with the recent one, the Kedo-S. So the present study aimed to compare and evaluate the post – operative pain after pulpectomy using K-files, MTwo files and Kedo-S files in deciduous molars. Material and Methods: 75 teeth were randomly divided into three groups (group A – K-files, group B - Kedo-S files and group C - MTwo files) for pulpectomy of primary molars. Post – operative pain was assessed every 6,12,24,48 and 72 hours using facial pain scale. Results: 44% of volunteers in K-file group had moderate pain followed by Kedo-S group that is 8% and then MTwo files that is 4%. Conclusion:  The least post-operative pain was found in Mtwo group followed by Kedo-S group and K-file group.KeywordsPulpectomy; Post-operative pain; MTwo; Kedo-S.
Influence of illuminants and different observers on the perception of surface gloss of resin composite
Authors: Tessarin Fernanda Bastos Pereira , Meirelles Laura Célia Fernandes , Rocha Rafael Santos , Caneppele Taciana Marco Ferraz , Bresciani Eduardo
Published: November 2018

Objective: To evaluate the visual perception of surface gloss of resin composite under different illuminants by different observers. Material and methods: twelve cylindrical specimens (6mm x 1mm) were fabricated using a nanofilled resin composite (Z350, A2E shade) in order to compare different observers and to determine the limit of perceptibility of surface gloss. Bovine tooth specimen with similar dimensions was obtained for the comparison of different illuminants. Polishing of resin specimens was performed resulting in 6 groups, presenting surface gloss values at 10, 25, 40, 55, 70, and 85 GU (gloss units), measured by glossmeter (NOVOCURVE). Fifteen individuals were selected: 5 lay-person, 5 undergraduate students, and 5 dental professionals. Participants observed the specimens in a light booth (Gti lightbox) under three different illuminants, and rated the possible combinations between resin specimens or with the bovine enamel specimen (85GU). Data obtained were analyzed by PROBIT non-linear regression analysis (?=0.05). Results: Differences were observed among types of illuminants (p=0.042) and ?GU (p=0.004), with no interaction between factors (p=0.139). The fluorescent light presented lower surface gloss perceptibility values in relation to incandescent light. There was no influence by type of observers (p =0.598). The surface gloss perception limit was 17.6 GU under the presented tested conditions. Conclusion: the illuminant type influenced perception of gloss, with lower percentage of perceptibility for fluorescent light, while such perceptibility was not influence by different observers. Keywords Illuminants; Observer variation; Composite resins; Surface gloss.
Uma proposição de análise do emprego de sistemas de gestão empresarial à luz da usabilidade de software
Authors: Longaray André Andrade , Da Silva Bruno Ferreira , Munhoz Paulo Roberto , Machado Catia Maria dos Santos , Tondolo Vilmar Gonçalves
Published: November 2018

Em um momento em que softwares informatizados impactam diretamente no sucesso das organizações, o presente estudo busca analisar a usabilidade dos softwares de gestão empresarial quanto aos aspectos de eficiência e eficácia da tarefa, visto que esta é uma forma de prevenção utilizada para minimizar erros no uso destes softwares. Para a realização do trabalho, os autores utilizaram a pesquisa aplicada como propósito do projeto, a fim de analisar a usabilidade de um software de uma empresa. O instrumento de pesquisa elaborado foi organizado em clusters, proporcionando uma análise mais aprofundada de cada aspecto examinado – eficiência, eficácia, satisfação do usuário e impacto do contexto de uso. Como contribuição do trabalho, tem-se o conhecimento do que precisa ser melhorado no sistema de forma que ele aprimore sua usabilidade e proporcione, de forma mais coerente, os quatro aspectos analisados pela investigação.
Estruturas locais condicionantes das características geométricas e hidráulicas do sistema Aquífero Guarani (SAG): alto estrutural da fazenda Santa Helena, município de Boa Esperança do Sul (SP)
Authors: Silva Flavio De Paula e , Silva Filho Flavio De Paula e
Published: November 2018

Denominou-se Alto Estrutural da Fazenda Santa Helena (AEFSH) à subestrutura identificada em subsuperfície por perfurações de poços para captação de água subterrânea no Sistema Aquífero Guarani (SAG), alojada no Alto do Jacaré-Guaçu na região das bacias hidrográficas dos rios Jacaré-Guaçu e Jacaré-Pepira, Município de Boa Esperança do Sul (SP). Ainda com extensão não delimitada, o AEFSH representa estrutura de pequeno porte que condiciona as características geométricas e hidráulicas do SAG. Dados de poços profundos e de perfilagem geofísica mostraram que o SAG está representado, na área, por arenitos finos a muito finos, argilosos, intercalados por frequentes camadas de argilito. Essa sucessão, pertencente à porção basal da Formação Piramboia, assenta-se sobre siltitos e argilitos da Formação Corumbataí. A espessura reduzida, da ordem de 80 m, e as características litológicas locais do SAG afetam negativamente a transmissividade do aquífero, resultando em poços com baixa produtividade. O presente trabalho dá conhecimento da existência dessa subestrutura que exerce influência no armazenamento hídrico e nas potencialidades locais do SAG, e chama a atenção para a possibilidade de haver inúmeras outras em contexto geológico similar ou ocultas sob a cobertura basáltica da Formação Serra Geral e sedimentar do Grupo Bauru.
‘A women’s war against war: The socialist-feminist pacifism of Four Lights: An Adventure in Internationalism’
Authors: Schreiber Rachel
Published: November 2018

The New York City Women’s Peace Party (NYC-WPP) published the first issue of Four Lights: An Adventure in Internationalism on 27 January 1917. The inaugural issue opened with the founders’ mission to ‘voice the young, uncompromising woman’s peace movement in America’ and declared the publication’s anti-war and anti-militarist position to be ‘daring and immediate’. In the short span of the nine months between January and October that Four Lights issued fortnightly numbers, its editors staked and held onto the staunch anti-war stance and Four Lights braided pacifism together with feminism. Their entwined anti-capitalist perspectives on gender, labour, class and race can be understood as anticipating intersectional feminism. Not nearly as well known as The Woman Citizen, The Suffragist and other publications of the women’s national suffrage and Progressive presses, Four Lights offers a fascinating glimpse into the thinking of the most ardent pacifists of the 1910s. This study of Four Lights illuminates this history and situates the journal’s critical place in the history of radical American periodicals.
Estudios de género: la sexualidad, lo femenino y la femeneidad. La apropiación del material de archivo y sus implicaciones desde la perspectiva del género
Authors: Coutel Évelyne
Published: December 2018

Este artículo analiza la apropiación de los archivos en el documental de compilación Con la pata quebrada, el cual permite comprobar las posiciones múltiples que las mujeres han podido ocupar en las películas españolas desde los años 30 hasta el siglo XXI, así como los discursos producidos sobre ellas dentro de esas películas. Se examina cómo el documental cumple, en primera instancia, con su intención manifiesta de dar cuenta del machismo subyacente en ciertas representaciones dominantes de la feminidad, en particular cuando subraya la perpetuación de arquetipos como el de la mujer fatal que se inserta dentro de una visión maniquea de la feminidad. Por otra parte, se estudian también los elementos que contradicen este proyecto de denuncia del machismo ibérico. Así sucede cuando el documental pone de realce la concepción del cuerpo femenino como espectáculo y su instrumentalización con fines políticos que caracterizan numerosas producciones de los años 70. A través del análisis de estos aspectos, se evidencia la ambigüedad tendencial del documental y sus efectos contraproducentes.
Documentos etnográficos y dispositivos de memoria. El uso de la imagen y los aportes de Walter Benjamin en los espacios culturales ­santafesinos:
Authors: De Jesús Jullier Yamila Del Corazón
Published: December 2018

El Tríptico de la Imaginación es un proyecto del Ministerio de Cultura e Innovación de la Provincia de Santa Fe. Está compuesto por tres espacios (El Molino, La Redonda y La Esquina Encendida), cada uno con características particulares que componen su estética, su propuesta pedagógica y artística. Este trabajo se propone analizar El Molino, Fábrica Cultural, donde el uso de la imagen es fundamental ya que carga de sentido al espacio, lo completa y articula con la técnica artesanal y la poética, conjugando así varias formas de vivir el arte y la artesanía. En El Molino se propone un acercamiento de la sociedad a los  espacios culturales, así como una nueva construcción de las miradas sobre el arte que rompen con las ideas tradicionales, las interpela y pone en  discusión. Procuro observar estas nuevas formas y miradas desde mi propia articulación conceptual, gestada enuna ­experiencia subjetiva con el espacio,  enlazando las corrientes de los Estudios Visuales, principalmente los aportes de Inés Dussel (2009), con la propuesta de Walter Benjamin (1936) sobre el  arte y la reproductibilidad técnica. Para ello me centraré particularmente en un dispositivo lúdico–pedagógico de El Molino: «La Gioconda y sus  intervenciones».
El cine: entre el relato histórico, el arte y la política. La producción de cine documental de los años 60 y 70 en Santa Fe:
Authors: Carril Alejandra Cecilia
Published: December 2018

Parafraseando a Badiou (2005), podemos decir que una mirada filosófica del siglo XX no se preocuparía tanto por saber qué pasó sino que se centraría en indagar qué se pensó en esa época. Analizar expresiones culturales puede darnos indicios de esa subjetividad así como del contexto histórico de  producción. Este trabajo pretende proximarse a la producción cultural de los años 60 y 70 en Argentina sin desconocer sus diálogos y contrapuntos con tendencias artísticas latinoamericanas y europeas. Centraremos la mirada en la producción cinematográfica de la época y analizaremos en particular una selección de filmes documentales realizados en las décadas del ’60 y ’70 en el marco de la Escuela Documental de Santa Fe perteneciente al Instituto de  Cinematografía de la Universidad Nacional del Litoral. En la primera parte se discuten las conceptualizaciones de cultura para definir un posicionamiento que permita indagar en torno a lasrelaciones entre arte y política en los años 60 y 70. En el segundo apartado se plantean las tensiones y los diálogos entre regionalismo e internacionalismo presentes en las expresiones artísticas de Latinoamérica en esos años y en particular en el nuevo cine latinoamericano. En tercer lugar se analiza de qué manera se evidencia la tendencia del nuevo cine latinoamericano en un corpus de realizaciones de la Escuela Documental de Santa Fe (Argentina, 1956–1976) con el fin de indagar las imbricaciones entre arte y política en los ’60–’70 a nivel regional (Litoral). En el apartado cuarto se exploran las opciones estéticas y estrategias retóricas empleadas en el corpus documental y se brindan elementos para poner en debate algunas nociones como cine político y cine militante. En el último apartado se plantea a modo de pregunta si en los filmes analizados es posible hablar de una actualización de los lenguajes cinematográficos y las estéticas europeas contemporáneas sin caer en la idea de subordinación a influencias extranjeras.
El pasado en imágenes.
Authors: Zimmermann Liliana
Published: December 2018

Presentación en FHUC, UNL, a cargo de la profesora Mariné Nicola del libro «Un cine hacia el socialismo. Imágenes del PRT–ERP», que tiene por compiladores a Pablo Russo, Juan Manuel Ciucci y Sebastián Russo, del Grupo Revbelando Imágenes.
Para una dialéctica de la igualdad. Revisitación del «antihumanismo»de Althusser cincuenta años después
Authors: Catanzaro Gisela
Published: December 2018

Este artículo interroga la tesis althusseriana del antihumanismo de Marx desde un punto de vista teórico: pensamiento de la diferencia contaminada entre teoría y política­, y político: interrogación del «valor» de la democracia y de la idea de igualdad. Recuperando la hipótesis de la «tachadura» como clave de lectura de los conceptos althusserianos propuesta por E. Balibar delineamos una «dialéctica de la igualdad» establecida entre tres instancias del planteo althusseriano que deben ser sostenidas simultáneamente: una «crítica de la desigualdad» despegada como conceptualización de los mecanismos estructurales de reproducción sistémicos en el capitalismo; una «crítica de la igualdad como ideología»; y una comprensión del discurso igualitarista como elemento inherente a las «prácticas políticas» emancipatorias, implicado asimismo en el lenguaje —constitutivamente «contaminado»— de la crítica.