bluuebunny/crossref_metadata_2025 huggingface dataset:
The Politics of Authenticity: Civic Individualism and the Cultural Roots of Gay Normalization
Authors: Seidman Steven , Meeks (1973-2007) Chet
Published: December 2017

Scholars and activists often assume that liberationism is the originating and guiding force in the gay and lesbian movement in the US. In fact, liberationism was but an ‘episode’ in the late 1960s and then again in the early 1990s. The abiding reality has been a politics centered on rights, identity normalization, pride, and social integration, or what we simply call a politics of normalization. Curiously, and perhaps expressing the above normative position, the research literature tends to ignore this rather stunning reality; instead researchers seem more disposed to explaining the waning of liberationism and lesbian feminism and their sustaining cultural force. With a few exceptions, social scientists have only recently addressed the social movement debates. We are encouraged by the promising and important research of sociologists and others. However, much of this recent social movement research has been one-sidedly social structural. In this article, we sketch a culturalist account of the ascendance of a normalizing politics 1 . We introduce the notion of a cultural code, specifically ‘civic individualism’, to explain something of the abiding historical presence of this politics. We trace this politics from the 1950s to the 1990s where ‘mainstream’ gay and lesbian politics has often relied on a moral language of virtue and authenticity.
Lung nodules: size still matters
Authors: Larici Anna Rita , Farchione Alessandra , Franchi Paola , Ciliberto Mario , Cicchetti Giuseppe , Calandriello Lucio , del Ciello Annemilia , Bonomo Lorenzo
Published: December 2017

The incidence of indeterminate pulmonary nodules has risen constantly over the past few years. Determination of lung nodule malignancy is pivotal, because the early diagnosis of lung cancer could lead to a definitive intervention. According to the current international guidelines, size and growth rate represent the main indicators to determine the nature of a pulmonary nodule. However, there are some limitations in evaluating and characterising nodules when only their dimensions are taken into account. There is no single method for measuring nodules, and intrinsic errors, which can determine variations in nodule measurement and in growth assessment, do exist when performing measurements either manually or with automated or semi-automated methods. When considering subsolid nodules the presence and size of a solid component is the major determinant of malignancy and nodule management, as reported in the latest guidelines. Nevertheless, other nodule morphological characteristics have been associated with an increased risk of malignancy. In addition, the clinical context should not be overlooked in determining the probability of malignancy. Predictive models have been proposed as a potential means to overcome the limitations of a sized-based assessment of the malignancy risk for indeterminate pulmonary nodules.
Pathobiology of pulmonary arterial hypertension: understanding the roads less travelled
Authors: Hemnes Anna R. , Humbert Marc
Published: December 2017

The pathobiology of pulmonary arterial hypertension (PAH) is complex and incompletely understood. Although three pathogenic pathways have been relatively well characterised, it is widely accepted that dysfunction in a multitude of other cellular processes is likely to play a critical role in driving the development of PAH. Currently available therapies, which all target one of the three well-characterised pathways, provide significant benefits for patients; however, PAH remains a progressive and ultimately fatal disease. The development of drugs to target alternative pathogenic pathways is, therefore, an attractive proposition and one that may complement existing treatment regimens to improve outcomes for patients. Considerable research has been undertaken to identify the role of the less well-understood pathways and in this review we will highlight some of the key discoveries and the potential for utility as therapeutic targets.
Metabolic dysfunction in pulmonary hypertension: from basic science to clinical practice
Authors: Chan Stephen Y. , Rubin Lewis J.
Published: December 2017

Pulmonary hypertension (PH) is an often-fatal vascular disease of unclear molecular origins. The pulmonary vascular remodelling which occurs in PH is characterised by elevated vasomotor tone and a pro-proliferative state, ultimately leading to right ventricular dysfunction and heart failure. Guided in many respects by prior evidence from cancer biology, recent investigations have identified metabolic aberrations as crucial components of the disease process in both the pulmonary vessels and the right ventricle. Given the need for improved diagnostic and therapeutic options for PH, the development or repurposing of metabolic tracers and medications could provide an effective avenue for preventing or even reversing disease progression. In this review, we describe the metabolic mechanisms that are known to be dysregulated in PH; we explore the advancing diagnostic testing and imaging modalities that are being developed to improve diagnostic capability for this disease; and we discuss emerging drugs for PH which target these metabolic pathways.
Development of an Algorithm to Distinguish Smoldering Versus Symptomatic Multiple Myeloma in Claims-Based Data Sets
Authors: Fiala Mark A. , Dukeman James , Tuchman Sascha A. , Keller Matt , Vij Ravi , Wildes Tanya M.
Published: December 2017

Purpose

The distinction of patients with symptomatic multiple myeloma (MM) from those with smoldering MM poses a challenge for researchers who use administrative databases. Historically, researchers either have included all patients or used treatment receipt as the distinguishing factor; both methods have drawbacks. We present an algorithm for distinguishing between symptomatic and smoldering MM using ICD-9-CM (International Classification of Diseases, Ninth Revision, Clinical Modification) codes for the classic defining events of symptomatic MM commonly referred to as the CRAB criteria (hypercalcemia, renal impairment, anemia, and bone lesions).

Patients and Methods

SEER-Medicare–linked data from 4,187 patients with MM diagnosed between 2007 and 2011 were used for this analysis.

Results

Eighty-four percent had ICD-9-CM codes consistent with CRAB criteria, whereas only 57% received treatment. Overall survival of patients with symptomatic MM defined as receipt of treatment was 32.3 months versus 26.6 months for the overall population and 22.9 months for patients with symptomatic MM defined by CRAB criteria. Conceptually, removal of patients with smoldering MM should result in a reduction in overall survival; however, the cohort of patients who received treatment tended to be younger and healthier than the overall population, which could have skewed the results.

Conclusion

The algorithm we present resulted in a larger and more representative sample than classification by treatment status and reduced potential bias that could result from including all patients with smoldering MM in the analysis. Although this study was performed using the SEER-Medicare database, the methodology was broad enough that the algorithm could be extended to additional claims-based data sets with relative ease.
The use of dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium in cardiac surgery patients over 60 years of age: a pilot study
Authors: Susheela Ammu T. , Packiasabapathy Senthil , Gasangwa Doris-Vanessa , Patxot Melissa , O’Neal Jason , Marcantonio Edward , Subramaniam Balachundhar
Published: December 2017

Background: Delirium is associated with many negative health outcomes. Postoperative sedation and opioid administration may contribute to delirium. We hypothesize that the use of dexmedetomidine and Intravenous acetaminophen (IVA) may lead to reduced opioid consumption and decreased incidence of postoperative delirium. This pilot study aims to assess feasibility of using dexmedetomidine and IVA in cardiac surgical patients, and estimate the effect size for incidence and duration of delirium.

Methods: A total of 12 adult patients >60 years of age undergoing cardiac surgery were recruited and randomized into 4 groups: Propofol only (P), Propofol with IVA (P+A), Dexmedetomidine only (D), Dexmedetomidine with IVA (D+A). Preoperative baseline cognition and postoperative delirium was assessed daily until discharge. The feasibility was assessed by the number of patients who completed the study.

Results: All patients completed the study successfully. The total incidence of delirium in the study population was 42% (5/12):  67% (2/3) in the group P, and 67% (2/3) in the group D, 33% (1/3) in  D+A group and 0%(0/3)  P+A group. The incidence of delirium was 17% (1/6) in the group receiving IVA compared to 67% (4/6) that did not receive IVA. The mean range of duration of delirium was 0-1 days. One patient expired after surgery, unrelated to the study protocol. One patient in the D group experienced hypotension (systolic blood pressure <90 mm of Hg.)

Conclusions: The feasibility of performing a  project is ascertained by the study. Patients receiving IVA had lower incidence of delirium compared to patients not receiving IVA which suggests that IVA may have a role in reducing the incidence of delirium. A prospective randomized, placebo-controlled trial will be the next step in investigating the role of dexmedetomidine and IVA in reducing the incidence of delirium.
Abstract Sifter: a comprehensive front-end system to PubMed
Authors: Baker Nancy , Knudsen Thomas , Williams Antony J.
Published: December 2017

The Abstract Sifter is a Microsoft Excel based application that enhances existing search capabilities of PubMed. The Abstract Sifter assists researchers to search effectively, triage results, and keep track of articles of interest. The tool implements an innovative “sifter” functionality for relevance ranking, giving the researcher a way to find articles of interest quickly. The tool also gives researchers a view of the literature landscape for a set of entities such as chemicals or genes. The Abstract Sifter is available as a Microsoft Excel macro-enabled workbook application.
Ocular surface symptoms among individuals exposed to ambient levels of traffic derived air pollution – a cross-sectional study
Authors: Paudel Nabin , Adhikari Sanjeev , Manandhar Sarina , Acharya Ashesh , Thakur Ajit , Shrestha Bhairaja
Published: December 2017

Background: The ocular surface is separated by a thin layer of tear film from outdoor air pollutants making individuals exposed to outdoor air pollution prone to various ocular surface disorders. The aim of this study was to determine the magnitude of ocular surface disorders symptoms among traffic police officers of Kathmandu, Nepal.

Methods: Two hundred traffic police officers working at different traffic police office branches of Kathmandu, Nepal were invited to the police headquarters for eye and vision examination. Among them, 91 individuals (95% males) completed the ocular surface disease index (OSDI) questionnaire and underwent Schirmer’s I tear test.

Results: Symptoms of ocular surface disorders were reported by over 80% of the individuals. Approximately two fifths of the individuals (38%) reported severe symptoms.  Only 17% of the individuals’ tear secretion was found to be below normal using the Schirmer’s tear test.  There was no association between the OSDI score and Schirmer’s tear test scores (r = 0.008, p = 0.94). A weak but significant relationship was observed between the OSDI score and job duration (r=0.21,p = 0.04). Individual exposed to outdoor air pollution for more than 10 years had higher odds of reporting ocular surface complaints as compared to those who were exposed for less than 10 years (OR = 3.94, p = 0.02).

Conclusion: Ocular surface disorder symptoms are common among traffic police officers of Kathmandu, Nepal. The duration of exposure appears to significantly contribute to the increased symptoms in this vulnerable population.
MORTALIDADE INFANTIL POR DOENÇA FALCIFORME NA BAHIA: UM ESTUDO EPIDEMIOLÓGICO
Authors: Ramos Jéssica Teixeira , Paes Geisiane Rodrigues , Jesus Fernanda Antônia de , Oliveira Daniela Sousa , Fernandes Emanuella Soares Fraga , Carvalho Barbara Teixeira , Fagundes Sinara Patrícia Alves Rocha Ávila
Published: December 2017

Descrever o perfil epidemiológico dos óbitos infantis por transtorno falciforme na Bahia em crianças menores de um ano de vida, nos anos de 2008 a 2013, registrados no Sistema de Informações sobre Mortalidade. Métodos: Trata-se de um estudo exploratório, transversal de cunho epidemiológico, baseado em dados de óbitos infantis por transtornos falciformes nos anos de 2008 a 2013, obtidos no Sistema de Informações sobre Mortalidade, com o acesso ao DATASUS, (e) analisados por meio da estatística descritiva. Resultados: Entre os casos de óbitos, 72,7% foram do sexo masculino, prevalecendo a raça/cor parda (54,5%) e faixa etária entre 28 a 364 dias de vida (90,1%). Conclusão: O estudo demonstra uma alta taxa de letalidade e prevalência da doença falciforme.
ANÁLISE ESPACIAL DA INCIDÊNCIA DA DENGUE EM UM MUNICÍPIO DE MÉDIO PORTE DO ESTADO DE SÃO PAULO DE 2008 A 2015
Authors: Defavari Elaine Regina , Fonseca Emílio Prado da , Da Silva Renato Pereira , Moreira Rafael da Silveira , Pereira Antonio Carlos , Batista Marília Jesus
Published: December 2017

Objetivo: Avaliar a incidência e distribuição espacial da dengue em um município do Estado de São Paulo. Metodologia: Estudo ecológico cujas unidades de análise foram os bairros em Piracicaba-SP, com uso de dados notificados da dengue à Vigilância Epidemiológica do município, no período de 2008 a 2015. Foram analisados coeficientes de incidências anuais. Para avaliar a condição socioeconômica dos bairros foi utilizado o índice de exclusão social (IEX). Análise espacial, testes de dependência espacial global e local foram realizados no Terraview (p<0,05). Resultados: Notificaram-se 11.397 casos no período, sendo que o maior coeficiente de incidência foi em 2015. Em 2008, a incidência de dengue foi 14,77/100 mil habitantes indo para 949,80/100 mil habitantes em 2015. No período de 2011 a 2013, os Índices Globais de Morran foram 0,28, 0,40 e 0,14 respectivamente (p<0,05). Não houve associação com o IEX. Conclusão: Houve um aumento expressivo da doença dengue nas regiões analisadas, se espalhando no município como um todo. Estratégias para o controle da doença devem ser populacionais.
Docente de Cinema: a relação possível entre emoção e razão
Authors: Pereira Ana Catarina
Published: December 2017

O presente artigo pretende ser um encontro entre metodologias e diretrizes pedagógicas para o Ensino Superior e a docência em licenciaturas de formação artística, mais especificamente, na área de Cinema. Habitualmente lecionados por antigos profissionais ou investigadores da área, sem uma formação pedagógica que os/as prepare para a exposição pública inerente à atividade de docente, nem tão pouco para a sistematização de conteúdos adequados ao corpo discente, estes cursos são também frequentados por alunos/as com necessidades, expectativas e referências heterogéneas, tornando particularmente necessários o debate e a reflexão sobre modelos e técnicas a aplicar em aula. No caso de estudo que aqui se apresenta, a regência da unidade curricular de História e Estética do Cinema Português, na Universidade da Beira Interior, atribui o mote a uma breve dissertação em torno de objetivos e metodologias com potencialidade de adaptação à formação de futuros/as cineastas. A tentativa de equilíbrio das vertentes teórica e prática, bem como a necessidade de preparação para o mercado de trabalho – no qual, por tratar-se de uma disciplina de final de curso, alunos e alunas irão previsivelmente entrar nos meses seguintes – têm ditado a evolução da experiência, permitindo-nos chegar a algumas conclusões sobre novos modelos educativos e a sua aplicação ao Ensino Artístico.
El diagnóstico relacional colaborativo (I)
Authors: Campos-Vidal José Francisco , Cardona-Cardona Josefa , Cuartero-Castañer María Elena
Published: December 2017

En la práctica del Trabajo Social, el concepto tradicional de diagnóstico remite a una sencilla fórmula: un profesional con una determinada competencia vinculada al saber y al hacer, emite un juicio en el cual se ha sintetizado e interpretado la naturaleza y la magnitud de las dificultades-necesidades de una persona, familia, grupo o comunidad. Esta visión no incorpora la dimensión relacional y cooperativa del encuentro entre el profesional y la persona en el marco de una relación de ayuda.Este artículo considera los desarrollos epistemológicos que se han planteado desde la perspectiva de la complejidad (Morin, 1981, 2009; Maturana y Varela, 2004), las tesis del Constructivismo (Piaget, 1971, 1978), el Construccionismo Social (Goolishian y Anderson,1990) y especialmente, las van - guardias de la práctica del Trabajo Social (de Shazer, 1982, 1985, 2009; White y Epston, 1990; White, 1995; Selekman, 1993).Desde la cibernética de segundo orden, la de los sistemas observantes, lo que los profesionales creemos, pensamos y valoramos (como profesionales y como personas), influye en la visión que vamos a construir de la persona/familia. Si la sub - jetividad se da, ¿que impide que la valoración de la situación problema pueda ser co-construirla colaborativamente entre el profesional y sus clientes?. Desde esta perspectiva, cabe hablar de diagnóstico colaborativo. El trabajo recoge los resultados de la aplicación práctica, en condiciones experimentales y en la práctica cotidiana de profesionales, de los criterios para desa- rrollar una co-diagnóstico. Es útil para guiar las conversaciones con los clientes y está abierto a los ajustes que cada relación necesite en su contexto.
GESTÃO MUNICIPAL E AÇÕES INTEGRADAS PARA O FORTALECIMENTO DO TURISMO NO TERRITÓRIO QUARTA COLÔNIA, RS, BRASIL
Authors: Dotto Dalva Maria Righi , Denardin Adriele Carine Menezes , Pons Mônica Elisa Dias , Ceretta Caroline Ciliane
Published: December 2017

Como elemento de desenvolvimento local, o turismo pode tomar a forma de roteiros integrados, estimulados pela governança local, com a oferta de bens e serviços para compor o produto turístico em parceria com a iniciativa privada. Este artigo tem como propósito analisar em que medida a atividade de turismo é compreendida como parte das discussões em torno do desenvolvimento da Quarta Colônia/RS/Brasil, uma vez que as lideranças políticas dos municípios usufruem de uma narrativa que o reconhece como parte integrada na perspectiva territorial de desenvolvimento. Os objetivos são identificar as principais ações em torno da atividade turística pensada de forma integrada no território Quarta Colônia; conhecer a visão da gestão pública sobre o uso do turismo como estratégia de desenvolvimento do território; e identificar se existem e como são realizadas as ações integradas para o fortalecimento do turismo no território. O estudo constitui uma perspectiva qualitativa de investigação, com aplicação de entrevistas semiestruturadas nas secretarias municipais de turismo desta região e análise descritiva e de discurso das informações obtidas. Os resultados da pesquisa demonstraram que a gestão do turismo nos municípios da região encontra-se desarticulada, com atuação discreta do poder público, refletindo em ações dispersas e com planejamento precário.
APROXIMAÇÕES ENTRE O TURISMO E A RESILIÊNCIA: UM CAMINHO PARA A SUSTENTABILIDADE
Authors: Sonaglio Kerlei Eniele
Published: December 2017

Neste estudo de aproximação entre o turismo e a resiliência se expõem a origem e os significados que esta última assumiu em tempos contemporâneos. Além disso, reflete-se sobre como as metodologias que examinam o comportamento resiliente de indivíduos ou das ações resilientes no ambiente podem ser incorporadas no turismo, no fito do turismo sustentável. Então, para dar suporte às reflexões, realizou-se pesquisa bibliográfica, eletrônica e documental. Assim, visando relacionar o turismo e a resiliência, reflete-se sobre a incorporação das abordagens da resiliência (como SOBRARE e UNISDR) no gerenciamento e no planejamento do turismo sustentável.
A equivalência tradutória de argentinismos
Authors: Novodvorski Ariel
Published: December 2017

Este texto traz uma análise fraseológica contrastiva, num corpus jornalístico paralelo e comparável, de publicações do jornal argentino Clarín, em suas versões em língua espanhola e portuguesa, acerca da trama política local. O foco do estudo reside na busca por equivalentes tradutórios, em unidades fraseológicas com marcas de argentinismos. São utilizados programas computacionais para análises lexicais, assim como recursos em corpora disponíveis on-line para verificação dos aspectos dialetais.
Tradução e Mercado
Authors: Mello Giovana Cordeiro Campos de
Published: December 2017

Este trabalho investiga parte da relação entre tradução e mercado de trabalho a partir da análise de quais efeitos de sentidos são postos em circulação quando a tradução é tomada como mercadoria e ocupação profissional no espaço dos sites de empresas de tradução. Com base na Análise do Discurso francesa de Michel Pêcheux, esta pesquisa tenta compreender as políticas das empresas de tradução, particularmente como tais empresas entendem e apresentam a tradução enquanto prática e produto em seus websites. Dado o desenvolvimento do campo dos Estudos de Tradução e o crescente interesse de alunos de graduação e de cursos livres em se tornarem tradutores, são relevantes estudos sobre a tradução percebida como trabalho e as possíveis mudanças no modo como a tradução é falada, entendida e realizada no espaço mercadológico.
A expertise por interação como condicionante da competência do tradutor de textos técnicos e científicos
Authors: Lourenço da Silva Igor Antônio , Silveira Francine de Assis
Published: December 2017

O presente artigo apresenta uma reflexão inicial sobre o papel da expertise por interação como componente necessário da competência do tradutor de textos técnicos e científicos. Mais especificamente, com base no modelo de expertise, preconizado por Collins e Evans (2007, 2010), e na noção de escrita mediante transformação do conhecimento, trazida por Scardamalia e Bereiter (1991), propõe-se que a interação entre tradutor e especialista em atividades de prática deliberada (ERICSSON; CHARNESS, 1997) fomenta processos tradutórios que levam à produção de textos de chegada adequados às expectativas das comunidades discursivas a que se destinam. Exemplos são apresentados para mostrar a pertinência da proposta e evidenciar que a expertise por interação é necessária para o sucesso da prática tradutória e para a elaboração de tarefas de prática deliberada voltadas à formação e à especialização de tradutores.
Traduzir os Charmes, de Paul Valéry
Authors: Faleiros Álvaro , Zular Roberto
Published: December 2017

Apesar da importância de Paul Valéry como um dos autores fundamentais do século XX, sua obra poética ainda circula pouco no Brasil, não havendo nenhuma tradução integral de seu mais importante livro de poemas – Charmes. Nosso intuito neste artigo é refletir sobre as possibilidades de tradução desse título e o que ele implica na concepção desse conjunto de poemas. Em nosso estudo, consideraremos tanto o título quanto o uso dessa palavra ao longo do livro.
Increasing the Sustainability of Aquaculture Systems: Insects as Alternative Protein Source for Fish Diets
Authors: Tschirner Martin , Kloas Werner
Published: December 2017

While aquaculture has a huge potential to contribute to the food security of our planet in the upcoming decades, it is still associated with various environmental concerns. The use of insects as a sustainable protein component in aquafeeds might change that.The fast growth of the
aquaculture sector worldwide increases the demand for aquafeeds. Since the production of conventional protein sources like fish meal is stagnating due to fully exploited fish stocks, far-reaching sustainable adaptions of production techniques as well as new alternative protein sources have
to be identified. A first step could be the production of omnivorous freshwater species with more modest feed requirements instead of carnivorous marine species. A next step could be the substitution of marine aquafeed ingredients. The popular practice to substitute fish meal by plant proteins
is, however, problematic from a nutritive physiological point of view. Moreover, feed crop production, for example, soybeans, has negative effects on land use and water consumption. Novel protein sources of animal origin are insect meals that combine a high nutritional value with small environmental
impact production systems.
Welche Macht führt zum Wandel?
Authors: Partzsch Lena
Published: December 2017

Reaktion auf vier Beiträge zum Thema Macht in Umweltpolitik und Umweltforschung in GAIA: L. Partzsch 24/1 (2015), A. Brunnengräber 26/1 (2017), P. Altmann 26/2 (2017), P. Wallmeier 26/4 (2017)
Transformative Wissenschaft: eine kritische Bestandsaufnahme der Debatte
Authors: Strunz Sebastian , Gawel Erik
Published: December 2017

Reaktion auf fünf Beiträge zum Thema Transformative Wissenschaft in GAIA
Bio-oil as Substitute of Phenol for Synthesis of Resol-type Phenolic Resin as Wood Adhesive
Authors: Dong Fangjia , Wang Mingcun , Wang Zhehui
Published: December 2017

The bio-oil from fast pyrolysis of cornstalks was used as substitute of phenol to synthesize resol resin as an ideal wood adhesive. The effects of formaldehyde/phenol (F/P) molar ratios and oil/phenol (O/P) weight ratios on rehology, thermal cure, thermal resistance and adhension of plywoods were investigated. With the increase of bio-oil used in bio-resol, the gel time of the prepared bio-oil modified resol resin (bio-resol resin) increased gradually, and the exothermic peak temperature of thermal cure shifted slightly higher. It was found that the bio-resin with bio-oil/phenol = 0.5 (weight ratio) and F/P = 1.5 (molar ratio) had the best comprehensive properties. The plywoods made with the bio-resol resins fulfilled the standards of E0 and type I plywood, implying the bio-resol resins was a new environment-friendly adhesive.
Clinical outcome in a series of pediatric patients with congenital generalized lipodystrophies treated with dietary therapy
Authors: Papendieck Laura , Araujo María B.
Published: December 2017

Background:

Congenital generalized lipodystrophy (CGL) produces clinical features with severe metabolic consequences. Research has focused on measuring the response to the drugs. Nevertheless, there are no studies on the response to dietary therapy. The aim of this study was to show the clinical response to early nutritional intervention to modify or reverse metabolic effects in pediatric patients with CGL.

Methods:

A retrospective study was conducted on patients with CGL followed up between January 2003 and June 2017. After diagnosis, patients were indicated a diet with a total calorie intake according to the reference daily intake (RDI), without fast sugars. Clinical feature and laboratory tests (insulin, glucose, A1C, lipid panel, liver and kidney function tests), and complementary studies (abdominal ultrasonography, echocardiogram), at the first visit and during follow-up were recorded. Statistics, version 10, was used for analysis.

Results:

Eight patients were included. The median age at the first visit was 1.1 years (range, 0.28–9.9 years) and the median time of follow-up was 3.9 years (range, 0.4–9.47 years). The median initial triglyceride level was 516 mg/dL (range, 327–3590 mg/dL) p=0.014; median low-density lipoprotein (LDL) was 157 mg/dL (range, 94–370 mg/dL) p=0.03; median glycemia was 84 mg/dL (range, 63–126 mg/dL) p=0.02; median insulin was 28.84 µUI/mL (range, 3.9–116); median homeostatic model assessment-insulin resistance (HOMA-IR) was 5.3 (range, 1.21–23.2). After 3–6 months of diet, the median percentage of triglyceride decrease was 79.5% (range, 47–97%), LDL 44% (range, 20.5–59%), glycemia 8.8% (range, 0–53.1%), insulin 67.8% (range, 0–92.8%) p=0.02 and HOMA-IR was 81.5% (range, 50–98%) p=0.05. As of the last follow-up visit, in none of the patients, liver ultrasonography or echocardiogram had deteriorated.

Conclusions:

In these pediatric patients with CGL, a diet adjusted to RDI with restriction of fast sugars led to a marked improvement in metabolic parameters.
The (3+3) commensurately modulated structure of the uranyl silicate mineral swamboite-(Nd), Nd0.333[(UO2)(SiO3OH)](H2O)2.41
Authors: Plášil Jakub , Petříček Václav , Locock Andrew J. , Škoda Radek , Burns Peter C.
Published: December 2017

The uranyl mineral swamboite has been redefined to swamboite-(Nd) and its structure has been solved and refined as a commensurate structure in six-dimensional superspace. The structure is monoclinic, superspace group P21
/m(a1,b1,g1)00(−a1,b1,g1)00 (a2,0,g2)0s, cell parameters a=6.6560(3), b=6.9881(5), c=8.8059(6), c=11.3361(16) Å, β=102.591(5)°, modulation wave-vectors q
1

=1/3 1/3 0; q
2

=−1/3 1/3 0; q
3

=1/2 0 1/2. The structure was refined from 8717 reflections to a final R=0.0610. The model includes modulation both of atomic positions and displacement parameters, as well as occupancy waves. The structure is based upon uranyl-silicate sheets of uranophane topology alternating with an interlayer of partly occupied Nd3+ sites and H2O molecules. The strong (3+3) dimensional modulation of the structure originates from the distribution of the Nd-dominated sites and further accommodation of the suitable geometry within the sheets and charge distribution within the structure. The separation distances between the corresponding occupied Nd sites are rationals of the super-cell vectors corresponding to the modulation vectors of the structure. The case of swamboite-(Nd) is the first example of a modulated structure within the oxysalts of U6+.
ENGAGING STUDENTS THROUGH EVENT MARKETING: AN EXAMPLE OF UNIVERSITY ENTREPRENEURSHIP EVENT
Authors: KOÇAK ALAN Alev , TÜMER KABADAYI Ebru , KÖKSAL Cansu
Published: December 2017

Despite the growing importance of event marketing, this study investigated the impact of entrepreneurship event on university students which was hosting by one of the leading university in Turkey. Three different assets of event image (event inventiveness, event appropriateness, event adequacy) were proposed to influence students’ satisfaction and revisit intentions. Research conducted to 468 students which participate in the entrepreneurship event for two days. For the analyses structural equation modeling technique was used. It was found that (i) the dimensions of event image (inventiveness, appropriateness, and adequacy) have an impact on students’ satisfaction and (ii) students’ satisfaction was a main driver of their revisit intention. Results, future researches and managerial implications were addressed.
The Y Chromosome Modulates Splicing and Sex-Biased Intron Retention Rates in Drosophila
Authors: Wang Meng , Branco Alan T , Lemos Bernardo
Published: December 2017

The Drosophila Y chromosome is a 40-Mb segment of mostly repetitive DNA; it harbors a handful of protein-coding genes and a disproportionate amount of satellite repeats, transposable elements, and multicopy DNA arrays. Intron retention (IR) is a type of alternative splicing (AS) event by which one or more introns remain within the mature transcript. IR recently emerged as a deliberate cellular mechanism to modulate gene expression levels and has been implicated in multiple biological processes. However, the extent of sex differences in IR and the contribution of the Y chromosome to the modulation of AS and IR rates has not been addressed. Here we showed pervasive IR in the fruit fly Drosophila melanogaster with thousands of novel IR events, hundreds of which displayed extensive sex bias. The data also revealed an unsuspected role for the Y chromosome in the modulation of AS and IR. The majority of sex-biased IR events introduced premature termination codons and the magnitude of sex bias was associated with gene expression differences between the sexes. Surprisingly, an extra Y chromosome in males (X^YY genotype) or the presence of a Y chromosome in females (X^XY genotype) significantly modulated IR and recapitulated natural differences in IR between the sexes. Our results highlight the significance of sex-biased IR in tuning sex differences and the role of the Y chromosome as a source of variable IR rates between the sexes. Modulation of splicing and IR rates across the genome represent new and unexpected outcomes of the Drosophila Y chromosome.
Comunicación alternativa, herramienta para la inclusión social de las personas en condición de discapacidad
Authors: Deliyore-Vega María Del Rocío
Published: December 2017

In a mainly oral society, those who use alternative forms of communication tend to be marginalized, and this limits equal opportunities. Therefore, this article is based on qualitative documentary research in which the problem posed determines how access to alternative and augmentative communication affects the social inclusion of people with disabilities. The objective is to determine the relationship existing between the theoretical assumptions about inclusive processes and their connection with alternative communication. To achieve this objective, the paper offers a compilation of updated sources on the subject the main researchers in the field have proposed. Subsequently, the contents involved are related using a conceptual scheme. Finally, an analysis of the data is carried out to achieve the proposed research objective. As a result, it was found that both national and international legislation, as well as research and pedagogical currents, promote equal opportunities and the inclusion of the population with disabilities. In spite of this situation, even people with communication barriers still do not have adequate access to dialogue. Results show that alternative communication is an indispensable right for a process of learning; however, students with communication barriers still attend classes without resources allowing their participation. It is also shown that there can be no learning without communication. Thus, the population with communication barriers that attend the classes without an assisted resource sees not only its right to expression violated, but also their right to education.
Variables influyentes en el miedo y el rendimiento infantil en Ceuta
Authors: Pulido-Acosta Federico , Herrera-Clavero Francisco
Published: December 2017

The low performance in different academic areas causes an enormous preoccupation; this situation promotes the search of new formulas for teaching interventions. These fast changes cause that students must learn new abilities and capacities that let them conform to this process in continuous evolution. From this perspective, with preoccupation for the little academic achievements, the emphasis is on the enormous importance that the emotions and their suitable control for the improvement of itself could have. The objective was to reflect on the predictors of fear and the academic achievement, and the influence over each other, in children aged 6 to 12 from Ceuta City. To do so, we had 404 participants: 47.8% were boys, 52.2% girls; 68.8% were Muslims, and 31.2% Christians. As tools, we implemented the Fear Survey Schedule for Children and Adolescents-II (FSSC-II), the version that Ascensio et al. (2012) adapted to the Spanish language; we also used the children’s grades. The results showed medium-high levels on all of the research variables. The first predictor of fear was gender. Other predictors were status, performance, culture, and age. The predictors of performance were culture, fear, status, and gender. Age worked as a predictor in three factors. We have found a significant relationship between fear and performance. All this leads to consider and increase the emotional competencies as a necessary measure to improve the students’ process of learning, a situation needed in our education system.
Importancia de la educación ambiental en la gestión del riesgo socio-natural en cinco países de América Latina y el Caribe
Authors: Ordóñez-Díaz Martha Melizza , Montes-Arias Luisa María , Garzón-Cortes Giovanna Del Pilar
Published: December 2017

Considering environmental education as a social tool allowing individuals to achieve a significant knowledge of the inhabited environment, to reduce the probability of occurrence of a disaster, and to respond to the presence of natural phenomena to which people are vulnerable, this article aims to generate a space for reflection on the importance of environmental education in the management of the social and natural risk in five countries of Latin America and the Caribbean. For this purpose, the paper presents a descriptive review of primary and secondary bibliographical sources referring to the performance of the management of social and natural risks related to environmental education in Colombia, Nicaragua, Mexico, Chile, and Jamaica between 1994 and 2015. In this period, a solid administrative and legislative organization of this management and environmental education is evident, but these two themes are clearly separated when implementing citizen projects: a situation that has generated shortcomings in the management of natural disasters, specifically under the principles of precaution and prevention. For this reason, this article offers a series of recommendations that include the dissemination of information, the creation of centers for the management of risk reduction, the strengthening of communication strategies, and the establishment of response plans and post-disaster recovery.
Entornos virtuales de aprendizaje complejos e innovadores: Una experiencia de creación participativa desde el paradigma emergente
Authors: Morado María Florencia
Published: December 2017

This paper starts with a participatory action research process, which aims to analyze the guidelines of the emerging paradigm and propose an alternative for building virtual learning environments (VLE) epistemologically consistent with this paradigm. Building virtual learning environments is presented as a challenge for teachers, especially for those who epistemologically adhere to the concepts of the emerging paradigm. Teachers find that the tools available encroach on their pedagogical and creative abilities. Two workshops were held with seven people who completed the research and the building process of their environments. In conjunction with the teaching staff, in the process were defined the guidelines of the emerging paradigm that were necessary to recover to build VLE; the teachers explored tools within the Moodle platform and others from Internet. Then, they co-constructed their environments in a recursive process of analysis and production.
Remoción de Cromo total en agua, usando carbón mineral activado con radiación de microondas
Authors: De la Torre Ostos Juan , Echevarría Flores Dante , Álvarez Bautista Jenny , Barreda Gutiérrez Nancy
Published: December 2017

Se estudió la remoción del cromo para validar el uso del carbón mineral activado mediante radiación de microondas, dicha técnica de activación fue usada anteriormente en la oxidación de nanotubos de carbono y carbón vegetal. Se buscó aplicar esta técnica en un carbón de origen mineral, procedente de las minas de carbón de la cuenca del Rio Santa – Ancash y mejorar las propiedades de remoción de dicho material, con lo que a largo plazo y a mayor investigación se lograría darle un uso aparte de la que actualmente es destinada. Las pruebas experimentales de activación resultaron exitosas, esto, reflejados en las cinéticas de remoción del cromo; los valores de capacidad de remoción determinadas en dichas cinéticas están entre el 34% para el carbón sin activar y el 41% para el carbón activado, la que indica que la capacidad de remoción depende mucho de la activación del material.
METODOLOGÍA SISTEMÁTICA “EMU” ENGRANAJE MERCADOLÓGICO UNIVERSITARIO
Authors: Pilco Wilian
Published: December 2017

Las universidades y escuelas politécnicas públicas para su funcionamiento y vigencia son evaluadas y acreditadas en base a un conjunto de criterios, indicadores y subcriterios de calidad que se enmarcan en una valoración objetiva, pero en su complemento es necesario aplicar una evaluación subjetiva para determinar los niveles de satisfacción de los usuarios atendidos, y en base a sus resultados diseñar estrategias de marketing universitario. El andamiaje metodológico se basó en una investigación aplicada de enfoque cuantitativo, una caracterización científica problemática – hipotética, se trabajó los métodos inductivo - deductivo, analítico, sintético y sistémico; un diseño no experimental y transversal con un nivel investigativo correlacional. El resultado obtenido es una metodología sistemática denominada “EMU”, para evaluar la imagen institucional y proponer estrategias de marketing universitario que permitan el fortalecimiento y posicionamiento de la calidad educativa y del desarrollo sustentable y sostenible de la universidad pública a favor de la sociedad ecuatoriana.
El desarrollo de la matemática informal en los niños
Authors: Malaspina Quevedo Martín
Published: December 2017

En el presente artículo se destaca la importancia del desarrollo del pensamiento matemático de los niños teniendo en cuenta que existen formas de aprender matemáticas que ocurren antes de vivir experiencias en la escuela, de una manera más natural, espontánea y recurriendo en gran medida a la observación y la imitación. Estos aprendizajes, llamados informales, tienen vital importancia para el adecuado aprendizaje formal de la matemática, que debe desarrollarse con base en ellos y teniendo en cuenta las emociones de los niños. Tales consideraciones deberían estar muy presentes en la formación inicial y continua de los profesores de educación infantil y así brindar mejores elementos para favorecer aprendizajes significativos y más agradables de la matemática en los niños.
Perspective Article: Flow Synthesis of Functional Materials
Authors: Sebastian Victor , Khan Saif A. , Kulkarni Amol A.
Published: December 2017

Continuous-flow synthesis of specific functional materials is now seen as a reliable synthesis approach that gives consistent product properties. This perspective article aims to survey recent work in some of the relevant areas and to identify new domains where flow synthesis of functional materials can be better than the conventional synthesis methods. It also emphasizes the need for developing high-throughput integrated synthesis and screening systems for almost all functional materials so that laboratory-scale recipes can be transformed into reliable manufacturing processes. New areas relevant to functional materials which have remained unexplored in flow synthesis are also highlighted.
Strategies for disguise in written threatening communications and ransom demands: an analysis of English and German texts
Authors: Marko Karoline
Published: December 2017

Awarding Institution: Department of English Studies, Heinrichstraße 36, 8010 Graz, Austria

Date of Award: 17 January 2017
Women, Rights Talk, and African Pentecostalism
Authors: Hackett Rosalind I J
Published: December 2017

In this essay, I seek to bring a rights perspective to women’s religious leadership and agency in Africa, notably in the case of the newer forms of Pentecostal-charismatic Christianity that now predominate in many parts of the continent. Rather than adopting a legal approach, I focus on the concept of “rights talk” which provides a more productive and inclusive way to approach ideas about women’s leadership in locally grounded (and often transnationally connected) African Christian communities. The protagonists are the women church founders and leaders who have publicly addressed the emancipation of women in the varying contexts of gender inequality. I contend that the way modern Pentecostal-charismatic women leaders argue for equality, justice, and dignity in their religious communities can also be traced back to their forbears in the African-initiated or independent churches that date from the seventeenth century onwards. There are interesting parallels, as well as some differences, in the ways that they frame, explicitly or implicitly, their understandings of equality and freedom from oppression, and balance compliance and resistance to perduring patriarchal limitations on their religious agency.
АНТИКРИЗОВЕ РЕГУЛЮВАННЯ ЕКСПОРТНО-ІМПОРТНОЇ ДІЯЛЬНОСТІ УКРАЇНСЬКОГО ВИНОРОБСТВА
Authors: Бондаренко С. А. , Руммо В. В. , Нізяєва В. Р.
Published: December 2017

У статті досліджено стан експортно-імпортної діяльності підприємств виноробної промисловості. На основі отриманих результатів виділено сучасні ризики, які необхідно враховувати при антикризовому регулюванні для забезпечення належного рівня експортної спроможності підприємств виноробної промисловості. Доведено, що регуляторний вплив на розвиток виноградарства та виноробстваслід зосереджувати, з одного боку, на безпосередній роботі із споживачем, а з іншого – на реструктуризації імпорту країни інструментами державного менеджменту.
ПРАВОВЕ ЗАБЕЗПЕЧЕННЯ КОНКУРЕНТОСПРОМОЖНОСТІ ПРОДУКЦІЇ МЯСОПЕРЕРОБНИХ ПІДПРИЄМСТВ УКРАЇНИ НА ЄВРОПЕЙСЬКОМУ РИНКУ
Authors: Дьяченко Ю. В.
Published: December 2017

В статті розглянуто структуру експорту агропромислової продукції та зміни в географії експортних потоків з України. Проаналізовано можливість вітчизняних підприємств харчової промисловості, втому числі м’ясопереробної галузі, бути конкурентоспроможними на зовнішньому ринку, зокрема ринкуЄвропейського союзу. Освітлено питання державного регулювання якості та безпечності харчовоїпродукції в Україні.
ДЕРЖАВНЕ РЕГУЛЮВАННЯ ІННОВАЦІЙНО-ОРІЄНТОВАНОГО РОЗВИТКУ ХАРЧОВОЇ ПРОМИСЛОВОСТІ УКРАЇНИ
Authors: Хрип’юк В. І.
Published: December 2017

У статті розглянуто теоретичні засади композиції державного регуляторного механізму активізації інноваційних процесів у визначених інституційних ланках харчової промисловості України. Визначені «сильні» та «слабкі» регуляторні важелі (через критеріальний базис світовизнаного Глобальногоінноваційного індексу), що формують інноваційний клімат у агропродовольчому секторі країни. Обґрунтовано перспективні напрями удосконалення державного регулювання інноваційного розвитку харчової промисловості України та з використанням авторського підходу визначені відповідні галузеві пріоритети.
W poszukiwaniu politycznego mechanizmu egzekucji unijnych wartości
Authors: Prostak Rafał
Published: December 2017

This research paper is a critical reflection on two attempts to fulfill the lack of an effective mechanism for monitoring and enforcing the Union’s values. The first attempt was made by J. W. Müller, who proposed to add a new body to Europe’s institutional system: the Copenhagen Commission. The second attempt originated from the European Parliament, which has urged the European Commission to submit, by September 2017, a proposal for the conclusion of the Union’s Pact for democracy, the rule of law and fundamental rights, in the form of an inter-institutional agreement.It is hard to predict if Müller’s Copenhagen Commission or the EP’s Pact will end up being incorporated into the Union’s system of values enforcement. Nevertheless, both attempts stand as clear proof that existing instruments are perceived as weak, and clearly point at the lack of elements that could make these instruments more effective. These are the main observations of the study.