bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of plasma LPL and GPIHBP1 in patients with pancreatitis
Authors: Tomohiko Matuyama  , Yuichi Fukuzawa  , Katshuhiro Gotoh  , Soichiro Uehara
Published: November 2023

Plasma LPL and GPIHBP1 levels and other lipid metabolic factors in patients with pancreatitis with blood triglycerides in the normal range were measured over time. The subjects included patients with acute pancreatitis (AP) (n=57) and chronic pancreatitis (CP) (n=30), and 20 healthy controls. Plasma LPL and GPIHBP1 were measured by enzyme-linked immunosorbent assay, apo protein by immunoturbidimetric assay, and other lipids by routine methods. Disease status was based on the APACHE-II score at the time of blood sampling. AP cases showed a significant decrease in LPL and GPIHBP1 compared to controls, whereas CP cases showed a non-significant decrease. ApoC2 II and III levels in patients with pancreatitis were lower than those in controls. LPL and GPIHBP1 levels were significantly positively correlated with each other, and both showed a significant negative correlation with the APACHE-II score. LPL and GPIHBP1 levels in pancreatitis survivors and non-survivors showed a trend towards a decrease with worsening disease and an increase with recovery. Serum triglyceride levels showed a non-significant negative correlation with LPL and GPIHBP1 levels. These results suggest that pancreatitis is related to abnormal lipid metabolism, mainly through a decrease in LPL in the course of the disease.
The Development of the Himpunan Mahasiswa Islam Organization in Medan City Post-Reformation
Authors: Azhar Muhammad Ridho , Achiriah Achiriah
Published: November 2023

The present study aims to analyze Himpunan Mahasiswa Islam's (HMI) development in Medan City after the reform era, employing a qualitative research design with a case study approach. This study showcases that HMI has developed significantly through in-depth interviews, document analysis, and field observations. The organization has demonstrated its ability to adapt to social, political, and cultural changes. HMI proactively participates in a wide range of social, political, and religious activities that contribute to the betterment of students, campuses, and the local community. By serving as a platform for political education, HMI in Medan City plays a pivotal role in facilitating thoughtful discussions and fostering the advancement of Islamic thought. Moreover, it acts as a catalyst for promoting constructive social change within its sphere of influence. HMI is firmly dedicated to promoting education, protecting students’ rights, and actively advocating for political and social reforms in Indonesia. This research offers valuable insights into the development of HMI in Medan City after the reform era, thereby contributing significantly to the comprehension of the role and potential of student organizations in driving social and political changes in Indonesia.
A Novel Authentication and Key Agreement Scheme for Countering MITM and Impersonation Attack in Medical Facilities
Authors:   Universiti Malaysia Sarawak, Maikol Steve Olsen , Khan Adnan Shahid ,   Universiti Malaysia Sarawak, Javed Yasir ,   Universiti Malaysia Sarawak, Anak Bunsu Anderson Lau ,   Universiti Malaysia Sarawak, Petrus Chelsten ,   Universiti Malaysia Sarawak, George Heindwick ,   Universiti Malaysia Sarawak, Jau Simon ,   Universiti Malaysia Sarawak
Published: November 2023

Authentication isused to enfold the privacy of the patient to implement security onto the communication between patients and service providers. Several types of research have proposed support for anonymity for contextual privacy in medical systems that are still vulnerable to impersonation attack and Man-in-the-middle attack. By using powerful technology that is used in medical facilities, it can help in building an advanced system. However, the same powerful tools can also be used by the attackers to gain personal profits and to cause chaos. The proposed countermeasure that is to be taken to prevent this kind of attacks is by implementing mutual authentication between users, their devices/mobile devices, and the system’s cloud server, and also a key agreement scheme together with the help of Elliptic Curve Cryptography (ECC). A novel authentication scheme which consists of two phases, a signature generation, and authentication process. The ECC implementation is to ensure that the keys are thoroughly secured and is not copy- able, together with a Key generation scheme that shields the system against impersonation attacks. The usage of Elliptic Curve Digital Signature Algorithm (ECDSA), in a signature generation, on the other hand, provides users more secure way to hide the user private key and bring additional security layer before proceeding to authentication phase due to the existence of extra elements of domain parameters. Authentication is still considered as a crucial component in maintaining the security of any critical facilities that require the CIA tried and non-repudiation as a need to maintain their data. It does not only apply to medical centers, but any organizations that possess valuable data that is needed to be protected also requires strong authentication protocols. Thus, the trend for the need of novel authentication protocols will keep on rising as technology gets fancier and fancier.
Assessing the added value of a history-based activity for students with low mathematics skills
Authors: De Vittori Thomas , Louaked Gaëlle , Visentin Marie-Pierre
Published: November 2023

The aim of this pilot study is to evaluate the relevance of the use of history in mathematics education. This paper presents an experiment carried out in France with sixth-grade students (n=108) in which an ancient number system is used, an approach that is commonly suggested in French sixth-grade textbooks but has previously been unassessed. Based on the data of a pre-test and a post-test surrounding an activity on an ancient Chinese numeration system, a statistical analysis using Rasch modeling shows a specific added value of the history of mathematics for students with low abilities in mathematics. For these students, a significant increase in observed abilities of +0.67 logit in mean is measured with a large effect size (Cliff delta +0.52). This effect is then weighted by considering the regression to the mean (RTM) effect, leading to a value around +0.14 logit in mean and a negligible effect size (Cliff delta +0.10). So, this pilot study shows the important effect of RTM, which suggests a very strong rebalancing of students’ results. In the last part of the paper, we discuss how RTM can nonetheless be positively interpreted in this specific context where students’ disorientation is one of the purposes of history in mathematics education.
INSTITUTIONALIZATION OF LOCAL WISDOM WEDDING PROCESSES IN CULTURE OF PUSAR VILLAGE, BATURAJA SUB-DISTRICT OGAN KOMERING ULU DISTRICT
Authors: Sakir Icuk Muhammad , Marleni Marleni , Pusnita Indah
Published: November 2023

Culture is a knowledge system that includes a system of ideas contained in the human mind, so that in everyday life culture is abstract. The wedding procession with sacrifice, the slaughter of a scapegoat for the people of Pusar Village is one of the traditions owned by the people of Pusar Village, Baturaja District. The approach used in the meaning of verbal and nonverbal communication in a series of marriage processions with sacrifices, the slaughter of scapegoats uses symbolic interaction theory, symbolic interaction theory holds that individuals form the same meaning through communication. The method used is descriptive qualitative method. In collecting data, conducting in-depth interviews (Depth Interview) to key informants, the selected informants are people who are considered to know and understand the problems studied. The results of the analysis in this study are marriage processions with sacrifices, slaughtering scapegoats in Pusar Village there are forms of verbal communication and nonverbal communication contained in every series of marriage processions with sacrifices, slaughtering scapegoats including prayer. The prayer delivered by the traditional leader and followed by the family holding a wedding ceremony aims to request permission to hold a wedding ceremony and share happiness with the ancestors. After taking turns praying, the family waters the graves of their ancestors with the water that has been provided. From the results of the research conducted, it can be concluded that in every series of wedding processions with sacrifices, the slaughter of a scapegoat has a meaning that has been believed by the people of Pusar Village itself. It is hoped that the people of OKU Regency can participate in preserving the existing culture and arts. Especially in the cultural arts of the wedding procession with sacrifice, the slaughter of this scapegoat.
TEACHERS’ ORGANIZATIONAL CITIZENSHIP BEHAVIOUR IN IMPLEMENTING DISTANCE LEARNING AT SMAN 1 CERME DURING THE COVID-19 PANDEMIC
Authors: Safira Amelia Rahmah , Asmorowati Sulikah , Suaedi Falih
Published: November 2023

The COVID-19 pandemic has impacted all aspects of people's lives, one of which is education. The implementation of education in the midst of the COVID-19 virus outbreak is carried out through distance learning. This study aims to describe the organizational citizenship behaviour and the factors behind the organizational citizenship behaviour of teachers in implementing distance learning at SMAN 1 Cerme during the COVID-19 pandemic. This research used qualitative with descriptive method type. Data was collected by direct observation, interviews with 21 informants, and through secondary data. The technique of determining the informant is carried out using a purposive technique by determining the key informant which develops into a snowball technique. The results of this study indicate that teachers at SMAN 1 Cerme have demonstrated organizational citizenship behaviour in the implementation of distance learning. This is shown from five dimensions, namely altruism, sportsmanship, courtesy, civic virtue, and conscientiousness. While the factors behind the teachers of SMAN 1 Cerme to carry out organizational citizenship behaviour in the implementation of distance learning during the COVID-19 pandemic were perceptions of organizational support, organizational culture and climate, job satisfaction and leadership.
EVALUATION OF QUALITY ASSURANCE OF PRIMARY SCHOOL EDUCATION IN PONOROGO REGENCY
Authors: Susilowati Tri Budhi , Handoko V. Rudi , Kusbandrijo Bambang
Published: November 2023

Quality assurance of national education is carried out to educate the nation's life and shape the character and civilization of a dignified nation through the SNP. The principle is to encourage managers, administrators, and education units to improve their performance in providing quality educational services and software to encourage transparency and public accountability. In its implementation, education quality assurance policies must adapt to changes and developments in science and technology and rapid global dynamics. The quality of Indonesian education has not been as expected. Accreditation to BAN-S/M, the development of school quality has not shown an encouraging development in the quality of education. The factor is not that the SNP is of low quality but that the fulfillment and implementation of the SNP have not been running optimally. The objective of this research is to: 1) Describe and analyze the evaluation of quality assurance policies for primary school education in Ponorogo; 2) Examine the factors that encourage and obstruct education quality assurance.; 3) look at the quality and functional education quality assurance model. This research uses a qualitative descriptive research method. The data analysis technique used was evaluation. Data were analyzed interactively.
EFFORTS OF BPJS KETENAGAKERJAAN IN SOCIALIZING OF AN OLD-AGE SECURITY PROGRAM TO INFORMAL WORKERS IN THE CITY OF MEDAN
Authors: Tambunan Riana
Published: November 2023

This study aims to determine the efforts BPJS Ketenagakerjaan in socializing the old age security program to informal workers in Medan City and the obstacles faced by Employment BPJS in socializing the old age security program. The research method used is descriptive qualitative. Data collection techniques are observation, interviews, and documentation. The results of this study indicate that the efforts BPJS Ketenagakerjaan in socializing the old age security program to informal workers in the city of Medan have been going well. The obstacles experienced by BPJS Ketenagakerjaan are the lack of public awareness regarding the culture of saving and the importance of the old age security program, the community only considers registering and does not consider this old age security as a necessity. This article contributes as an additional reference that can help BPJS Ketenagakerjaan to find an innovation in socializing the JHT program and the constraints that occur according to the community's perspective.
TRANFER PRICING
Authors: Kristawati
Published: November 2023

jumlah uang yang digunakan untuk menjelaskan setiap transfer barang/jasa antar RC, atau Nilai uang yang dilekatkan pada suatu transfer barang/jasa pada transaksi yang melibatkan setidaknya salah satu dari kedua pihak yang terlibat adalah sebuah PL Harga itu mencari elemen laba
PENGARUH FAKTOR EKONOMI TERHADAP KEADILAN SOSIAL DALAM PELAYANAN KESEHATAN
Authors: Tewa Teresia Aflinggia
Published: November 2023

Pengaruh Faktor Ekonomi Terhadap Kehidupan Sosial dalam Pelayanan Kesehatan Makalah ini membahas dampak signifikan dari faktor ekonomi terhadap kehidupan sosial dalam konteks pelayanan kesehatan. Penelitian ini menganalisis bagaimana ketidaksetaraan ekonomi mempengaruhi akses, kualitas, dan penerimaan pelayanan kesehatan di masyarakat. Melalui pendekatan studi literatur dan analisis data, makalah ini mengungkapkan bahwa ketidakstabilan ekonomi dapat menyebabkan penurunan akses terhadap layanan kesehatan yang berkualitas. Dalam kondisi ekonomi yang tidak stabil, masyarakat dengan pendapatan rendah memiliki keterbatasan dalam mengakses perawatan medis yang diperlukan, sehingga meningkatkan risiko penyakit dan kematian prematur. Selain itu, faktor ekonomi juga memengaruhi aspek kehidupan sosial seperti pendidikan, pekerjaan, dan kondisi lingkungan. Ketidaksetaraan ekonomi dapat menciptakan disparitas dalam pendidikan kesehatan dan kesadaran masyarakat, membatasi peluang pekerjaan yang layak, dan menciptakan lingkungan yang tidak sehat. Dalam konteks ini, makalah ini menyoroti pentingnya kebijakan publik yang mendukung distribusi ekonomi yang adil, peningkatan akses terhadap pendidikan kesehatan, dan peningkatan kualitas layanan kesehatan untuk semua lapisan masyarakat.Penelitian ini memberikan pemahaman yang lebih mendalam tentang kompleksitas hubungan antara faktor ekonomi dan kehidupan sosial dalam pelayanan kesehatan. Implikasi temuan ini adalah perlunya upaya bersama dari pemerintah, lembaga kesehatan, dan masyarakat untuk menciptakan sistem kesehatan yang inklusif, adil, dan berkelanjutan, sehingga semua individu dapat memperoleh pelayanan kesehatan yang layak tanpa memandang latar belakang ekonomi mereka.
Multi-fold Dark Matter and Energy Effects Fit The Ratios to Normal Matter in the Universe
Authors: Maes Stephane
Published: November 2023

In a multi-fold universe, gravity emerges from Entanglement through the multi-fold mechanisms. As a result, gravity-like effects appear in between entangled particles, whether they be real or virtual. Long range, massless gravity results from entanglement of massless virtual particles. Entanglement of massive virtual particles leads to massive gravity contributions at very smalls scales. Multi-folds mechanisms also result into a spacetime that is discrete, with a random walk fractal structure and non-commutative geometry that is Lorentz invariant and where spacetime nodes and particles can be modeled with microscopic black holes. All these recover General Relativity (GR) at large scales and semi-classical models remain valid till smaller scale than usually expected. Gravity can therefore be added to the Standard Model resulting into what we define as SMG. This can contribute to resolving several open issues with the Standard Model without New Physics other than gravity, i.e. no new particles or forces, or with the standard cosmological model (ΛCDM) in terms of dark matter and dark energy. The present paper provides estimates for the ratios of normal matter to multi-fold dark matter effects (~ 1 to 5) and to dark energy (~ 1 to 14). These ratios match the estimates for our real universe, in particular the Λ-CDM model. Such results increase the relevance of multi-fold theory. To our knowledge, being able to predict such ratios, ab initio, i.e., solely based on the underlying microscopic mechanisms is not a small feat, and the reasonings presented in this paper, would not be applicable to ratio estimates from the other mainstream theories. It is a strong validation of the multi-fold theory, and its potential applicability to our real universe and its cosmology. It also validates the E/G conjecture with its proposal that entanglement creates gravity like effects.
Optimizing Inventory Management Practices for Pharmaceuticals in Saudi Arabian Pharmacies
Authors: Ayuba Adegoke , Kelvin Lawrence , Tera Terry
Published: November 2023

This article explores pharmaceutical inventory management in Saudi Arabian pharmacies, with a specificfocus on Jeddah. It delves into the challenges unique to this region and identifies best practices foroptimizing inventory while balancing costs and medicine availability.The study begins by emphasizing the significance of inventory management in healthcare. It aims to strike abalance between cost control and ensuring a steady supply of essential medicines in Saudi pharmacies,particularly in Jeddah.The literature review covers global and local inventory management practices and their relevance. Ithighlights the importance of inventory turnover, demand forecasting, and technology adoption.The research methodology section describes how the study was conducted, including case studies in Jeddahpharmacies.Findings reveal common challenges and best practices, with case studies illustrating effective strategies.The discussion section analyzes the impact of inventory optimization on cost reduction and medicineavailability. It also considers the role of technology and regulations.The conclusion summarizes key findings, emphasizing the importance of optimized inventory managementfor both cost efficiency and public health. Recommendations are provided for pharmacy stakeholders andpolicymakers.In summary, this article contributes to the discussion on pharmaceutical inventory management, offeringpractical insights for Saudi pharmacies, especially those in Jeddah.
MANAGERS AS LEADERS
Authors: Setiyani Nanda Auliya
Published: November 2023

MANAGERS AS LEADERS
INDIVIDUAL DECISION MAKING
Authors: Widianti Indri
Published: November 2023

Pengambilan keputusan adalah Sebuah proses sadar membuat pilihan antara satu atau lebih alternatif dengan tujuan bergerak menuju beberapa keadaan yang diinginkan.
INOVASI MEDIA PEMBELAJARAN DI ERA DIGITAL
Authors: Ariffullah Muhammad Nor
Published: November 2023

Artikel ini menekankan pentingnya inovasi media pembelajaran di era digital, menyoroti peran teknologi dalam transformasi pendidikan dan perlunya metode pembelajaran adaptif. Dibahas tentang pentingnya media pembelajaran interaktif dan inovatif dalam meningkatkan keterlibatan dan motivasi siswa. Artikel ini juga memberikan contoh media pembelajaran inovatif, seperti YouTube, pembelajaran berbasis permainan, pembelajaran berbasis video, dan pembelajaran berbasis virtual reality. Artikel ini diakhiri dengan menekankan pentingnya pendidikan yang berkualitas dan efektif serta peran media dalam mencapai tujuan ini.
Pengaruh Kompetensi Kepribadian Guru PAI terhadap Pembentukan Karakter Siswa
Authors: Masnur Zahra Ramadini , Obaid Moh. Yahya , Ilham Muhammad
Published: November 2023

Penelitian ini bertujuan untuk mengkaji pengaruh kompetensi kepribadian guru pendidikan agama Islam terhadap pembentukan karakter siswa kelas VIII di SMP Negeri 1 Satap Sindangkasih. Penelitian ini merupakan penelitian kuantitatif dengan metode deskriptif. Pengumpulan data dilakukan dengan observasi, dokumentasi dan angket yang disebar pada 34 sampel yang dijadikan objek penelitian. Data penelitian dianalisis dengan menggunakan rumus regresi linier sederhana. Hasil penelitian ini menunjukkan bahwa kompetensi kepribadian guru pendidikan agama Islam mempunyai pengaruh terhadap pembentukan karakter siswa dengan kontribusi sebesar 22%, sedangkan sisanya (78%) dipengaruhi oleh variabel lain. Maka hipotesis yang diterima dalam penelitian ini adalah hipotesis alternatif (Ha: ρ ≠ 0) yakni terdapat pengaruh kompetensi kepribadian guru PAI terhadap pembentukan karakter siswa. Kata Kunci: Kompetensi Kepribadian, Karakter Siswa.
أثر "الكوتشينج" الإداري على تعزيز القدرة الوظيفية: دراسة تطبيقية في سوق العمل السعودي
Authors: فطاني براء صلاح , الربيعي بندر بن محمد
Published: November 2023

الأهداف: يركز البحث الحالي على دراسة أثر الكوتشينج الإداري على تعزيز القدرات الوظيفية كالقدرة على الأداء والابتكار. يفترض هذا البحث أن هناك تحولًا ملحوظًا نحو تعزيز أدوار القائد المُوَجّه والمدرب وذلك استجابةً لتحديات بيئة الأعمال المعاصرة والمتسمة بالتنافسية وحالة عدم اليقين. تساهم هذه الدراسة في إثراء الأدبيات العلمية حول تغير الأدوار التقليدية للمدير في مكان العمل، سيما أنَّ المنظمات تتجه نحو تفويض بعض مسؤوليات إدارة الموارد البشرية إلى المدراء. هذا يعني من ناحية عملية توسع مسؤولياتهم عن أداورهم التقليدية من مجرد الرقابة، والتخطيط، وتقييم الأداء إلى المساهمة الفاعلة في تدريب الموظف وتطوير مهاراته وقدراته. لهذا هدفت الدراسة إلى تحليل أثر أبعاد الكوتشينج الإداري (التواصل المفتوح، نهج الفريق، قيمة الناس، قبول الغموض، وتيسير التطوير) على القدرة الوظيفية للموظفين التابعين لهم (متمثلة في بُعدين اثنين: القدرة على الأداء، والقدرة على الابتكار). المنهجية: من أجل تحقيق أهداف الدراسة؛ قام الباحث باستخدام المنهج الوصفي التحليلي وتم تطبيقها على عينة عشوائية تكونت من (270) مفردة من العاملين في سوق العمل السعودي. النتائج: أظهرت النتائج أنه يُوجد أثر ذو دلالة إحصائية عند مستوى الدلالة ( ألفا أقل أو يساوي من 0.05) للكوتشينج الإداري بأبعاده الخمسة على القدرة الوظيفية المتمثلة في القدرة على الأداء والقدرة على الابتكار. الخلاصة: بناءً على هذه النتائج؛ خَلُصَت الدراسة إلى أنَّ المدراء الذين يمارسون الكوتشينج يتواصلون بفعالية مع موظفيهم ويعطونهم قيمة أكبر مع الحرص على تطويرهم، كما أنهم يهتمون بتعزيز نهج العمل القائم على الفريق. الدراسة أظهرت كذلك أهمية ممارسة المدراء لمهارات الكوتشينج فهي من جانب تمكنهم من إتاحة الفرصة لمرؤوسيهم في مشاركة الآراء البناءة مهما كانت تخالف وجهات نظرهم؛ مما يعزز قدراتهم الوظيفية، ومن جانب آخر فإنهم يميلون إلى تجربة الحلول المبتكرة والإبداعية في حل المشاكل التي تواجههم والميل لتشجيع مرؤوسيهم على أخذ المخاطرة وتجربة حلول جديدة؛ مما يعزز قدراتهم الابتكارية.
1980-2010 Yılları Arasında OECD Ülkelerinde Bulunan Farklı Vasıf Kategorilerindeki Türk İş Gücünün Göç Eğilimlerinin Sosyolojik İncelenmesi
Authors: COŞKUN Serkan
Published: November 2023

Bu çalışma 1980-2010 yılları arasında OECD ülkelerine göç eden Türk göçmen stokunun göç eğilimlerini makro iktisadi parametrelerde meydana gelen dönüşümler ile etkileşimi çerçevesinde ele almaktadır. Neoliberal politikalar ve küreselleşen dünya dinamikleri, günümüz göç sürecinin sistemler ve ağlar arası bir etkileşim bağlamında değerlendirilmesinin zorunluluğunu ortaya çıkarmıştır. Bireylerin göç sürecinde izledikleri stratejiler sistemler arasındaki yapısal boyutlar değişimi çerçevesinde şekillenmektedir. Bu kapsamda 1980-2010 yılları arasında 19 OECD ülkesindeki Türk göçmen stokunun yığılım gösterdiği alanları, vasıf ve cinsiyet kategorilerini içeren panel veri seti kullanılmıştır. Araştırma sonuçlarına göre 1980-2010 yılları arasında Türk göçmen stoku şu değişimleri kaydetmiştir: (1) Ülke profili açısından yayılım alanını genişletmiş ve devletler arası anlaşmalardan bağımsızlaşmıştır, (2) Cinsiyetler açısından göçün ciddi bir feminizasyonu söz konusu olmuş ve kadın-erkek kategorileri arasındaki farkın yıllar içerisinde kapandığı görülmüştür, (3) Göçmen stokunun vasıf kategorileri arasında ayrım yıllar içerisinde şiddetlenmiştir. Düşük ve orta vasıf kategorileri yıllar içerisinde yüksek vasıflı göçmen stokuna dönüşmüş ve bu eğilim giderek artmıştır, (4) Göçmen stokunda yüksek vasıflı kişilerin yıllar içinde hızlı yükselişinin merkez ülkelerin ekonomik kalkınma anlayışındaki değişimler ile paralellik gösterdiği gözlemlenmiştir, (5) Göçmen stoku yıllar açısından düşük vasıflıdan yüksek vasıflıya dönüşüm geçirirken yığılımlarını etkileyen faktörler açısından kendi içlerinde de farklılaştığı tespit edilmiştir.
Incorporate Social Media-Movie-Based Learning Projects (SMMBLPS) into Online Instruction to Engage Students in Higher Education
Authors: Andi Asrifan  , Anita Candra Dewi
Published: November 2023

The development of ICT-based English Language Teaching (ELT) materials in Indonesian higher education continues. During the COVID-19 pandemic, virtual learning environments are integrating more tools, apps, and technology. This study examines the effects of adding a social media-movie-based learning project (SMMBLP) to computer science instructors' virtual learning environments to improve students' English proficiency. This quantitative study uses a pre-experimental design to examine how SMMBLP affects ELT students' English proficiency and motivation. This study analyzed 40 first-semester Computer Science students at Universitas Muhammadiyah Sidenreng Rappang in 2020–2021. Data was collected using a questionnaire, pre-test, and post-test. The study found that social media and movie-based learning projects (SMMBLPs) improved students' motivation and English ability. According to the study, EFL students learning ELT could use SMMBL in a blended or online environment as the next pedagogical model.
Bioactive Potentials of Petunia Integrifolia (Hook.) Schinz & Thell. Against Culex Quinquefasciatus Larvae, Artemia Salina Nauplii and Poecilia Reticulata Adults
Authors: Islam Alimul Islam , Yasmin Nelufa Yasmin , Islam Nurul Islam
Published: November 2023

Petroleum ether (pet. ether), chloroform (CHCl3) and methanol (CH3OH) extracts of Petunia integrifolia (Hook.) Schinz & Thell. Whole plant was subjected to assess cytotoxicity against the brine shrimp Artemia salina L. nauplii, larvicidal activity against the mosquito Culex quinquefasciatus Say larvae and piscicidal activity against the Poecilia reticulata Peters adults. The P. integrifolia extract in pet. ether showed the highest cytotoxic activity against A. salina nauplii by giving the minimum LC50 value of 49.25 parts per million (ppm) at 48 h, while in case of CHCl3 and CH3OH extracts, the values were 63.37 and 342.55 ppm, respectively. Against C. quinquefasciatus larvae the three extracts gave LC50 values of 4.92, 5.51 and171.26 ppm, respectively all after 48 h of exposure. Against P. reticulata the LC50 values were 21.70 ppm for pet. ether extract at 48 h, and 31.91 ppm for CHCl3 extract after 42 h of exposure but CH3OH extract offered no mortality. According to the intensity of activity, therefore, the extracts could be arranged in the descending order of: pet. ether > CHCl3 > CH3OH extracts; and the sensitivity of the test organisms to the extract of P. integrifolia could be arranged in the following descending order: C. quinquefasciatus larvae (in Pet. ether; LC50 = 4.92 ppm) > P. reticulata (in pet ether; LC50 = 21.70 ppm) >A. salina nauplii (in pet. ether; LC50 = 49.25 ppm)
J. Bio-Sci. 31(1): 99-108, 2023
Análisis del Potencial Fotovoltaico de los Campus Universitarios de la Universidad Estatal del Sur de Manabí, Jipijapa
Authors: Guerrero-Calero Juan , Gras-Rodriguez Rene , Cruz-Macias Bryan , Cabrera-Verdezoto Rodrigo
Published: November 2023

La producción de electricidad mediante el empleo de sistemas solares fotovoltaica es da en función  al estudio de irradiación electromagnética, misma que se ha convertido en una de las principales alternativas de energía renovable, para contrarrestar los efectos del calentamiento global, al tratarse de un recurso prácticamente ilimitado que no emite gases de efecto invernadero y se encuentra disponible en todo el planeta, donde es indispensable identificar las zonas geográficas con potenciales solar, adecuados para su aprovechamiento.  
El estudio titulado “Análisis del potencial fotovoltaico de los Campus de la Universidad Estatal del Sur de Manabí”  tiene como objetivo de analizar el comportamiento de la irradiación solar histórica durante el periodo 2012 – 2022,  con información adquiridas de estaciones meteorológicas y la plataforma Power Data Access Vierwer, para determinar la el potencial energético de los Campus Universitarios, con la proyección de implementar en las edificaciones del centro de educación superior sistemas fotovoltaicos, utilizando los métodos cualitativo- cuantitativo y potencial, permitieron analizar los datos estadísticos del área de estudio, calculado la irradiación global o potencial energético existente en cada uno de los campus universitarios, obteniendo como resultado que el campus Los Ángeles y El Complejo mantiene un mayor potencial con 4065 W/m2 a diferencia de Edificio Central 3998 W/m2 y Divino Maestro 3990 W/m2, contrastando los resultados  con  el software estadísticos SPSS 21, Minitab 19 y el programa ArcMap 10.8 definiendo las horas solares pico (HSP), y potencial energético existente.
Análisis de la Brecha Educativa por Pandemia de los Estudiantes de Bachillerato Utilizando Inteligencia de Negocios
Authors: Saquisili-Ortega Jennifer , Ávila-Correa Blanca
Published: November 2023

La pandemia de COVID-19 tuvo un profundo impacto en diversos sectores de todo el mundo, entre ellos la educación.  En efecto, en el Ecuador la virtualidad no fue fácil; muchos estudiantes especialmente de los sectores marginales no tuvieron acceso a la educación en línea y debido a lo inesperado del suceso, muchas instituciones educativas se vieron obligadas a improvisar para adaptarse a la situación, implementando estrategias metodológicas de enseñanza de forma apresuradas y sin contar con la suficiente capacitación y recursos. El objetivo de esta investigación es determinar la incidencia de la brecha digital en el aprendizaje de los estudiantes de bachillerato del sector urbano del cantón Azogues, a través métodos y herramientas de inteligencia de negocios que permitan la toma de decisiones informada. Para ello, se realizó el análisis descriptivo de información histórica referida al rendimiento académico obtenido antes, durante y después de la pandemia para identificar el período en el que se produjo la brecha educativa y, con la aplicación de instrumentos de observación debidamente validados, se analizaron los factores asociados a las deficiencias de aprendizaje referidos a la no disponibilidad de recursos tecnológicos, la inadecuada implementación de estrategias metodológicas y aspectos emocionales de los estudiantes. Los resultados demuestran el impacto que produjo la pandemia en la calidad de la educación, a la vez que proporcionan un punto de referencia sobre los aspectos que deben ser considerados en los entornos virtuales, de modo que promuevan el protagonismo de los estudiantes y el cumplimiento de resultados de aprendizaje planteados. El modelo multidimensional del estudio permitirá a las autoridades competentes contar una herramienta de monitoreo y seguimiento del rendimiento académico para una continua toma de decisiones informada.
TINJAUAN YURIDIS TERHADAP PELANGGARAN HAK ASASI MANUSIA YANG DILAKUKAN OLEH APARAT PENEGAK HUKUM KEPADA DEMONSTRAN DI KOTA TANGERANG BERDASARKAN TEORI SOSIOLOGI HUKUM
Authors: Hutabarat Binsar Mariz Juan Alfredo , Komariah Mamay , Indayatun Ratna
Published: November 2023

Human rights are every human's. His existence is an absolute thing. But in application, human rights abuses continue to occur. Human rights abuses are also carried out by law enforcement officials to demonstrators. What factors have led to the action of human rights abuses by law enforcement officials to demonstrators on the basis of law sociology theory and how the law's certainty to law enforcement officials on human rights became the object of study. Then the study may be useful for the development of law science, law enforcement officers as well as for demonstrators or communities. The study adopted an empirical juridical approach. Studies are conducted by conducting interviews with relevant sources as well as books and laws as research guides. The theories used in this study are the theories of law sociology, of certainty of law and of justice. Research suggests that the spontaneous process of human rights abuses by law enforcement officials has been carried out by demonstrators. Legal certainty for law enforcement agencies that violate human rights has also been done according to action. However, law enforcement officials need to be more patient with guarding demonstrations in order to resort to violence or unlawful behavior of any thinks.

Keywords: Human Rights; Law Enforcement Officials; Demonstrators.
Evapotranspiration and Yield Impact Tools for More Water-Use Efficient Alfalfa Production in Desert Environments
Authors: Montazar Aliasghar , Putnam Daniel
Published: November 2023

Drought and climate change have decreased water availability for agriculture, especially in the desert of southwestern USA. Efficiency enhancements in irrigation management aimed at conserving water are key to adjust to limits in water supply, improve profitability and sustainability of alfalfa production in arid and semiarid areas. This study intended to conduct a field-scale analysis to develop yield and ET estimation tools for the effective use of irrigation water in a desert alfalfa production system. Extensive data collection and trials were carried out over three years in nine fully irrigated commercial alfalfa fields in the low deserts of California. The seasonal crop water consumption measured using the residual of energy balance method varied from 1381 mm to 1596 mm across the experimental sites and crop seasons. Variable seasonal dry mater (DM) yields ranged from 23.01 Mg ha−1 to 29.90 Mg ha−1. The results indicated that the first five cuttings each year were the most productive cuttings with a mean DM value ranged between 3.29 (cut 1) and 4.21 (cut 4) Mg ha−1 but declined in later cuttings. An average annual water productivity (WP) value of 17.0 kg ha−1 mm−1 was determined across the sites varying from 15.5 to 18.9 kg ha−1 mm−1. The findings suggested that one may lose up to 1.44 Mg ha−1 alfalfa yields with moderate summer deficit irrigation strategies, using 40% less water applied than full irrigation practices over the summer period of July–September. A more severe summer water deficit, with no irrigation event over the summer period of July–September may result in a potential water savings of 0.234–0.246 (ha·m) ha−1 and 19–21% seasonal yield losses in the desert environment. This study describes the seasonal yield pattern, the crop water use-production function, and the crop coefficient values for various harvest cycles over the crop season. These tools may assist farmers to quantify water savings and estimate yield losses for more accurate and effective irrigation management strategies to meet water conservation objectives and for the resiliency of alfalfa production in the desert region.
Germination Strategy of Chenopodium acuminatum Willd. under Fluctuating Salinity Habitats
Authors: Tian Yu , Li Yang , Zhang Hongxiang , Tennakoon Kushan U. , Sun Zewei
Published: November 2023

Germination events of plants often occur after rainfall in saline environments where the soil salinity is diluted, viz recovery germination. Previous germination studies have rarely considered the duration of exposure to salt stress, and none of them have investigated recovery germination under low-salt concentration, other than in distilled water. The main objective of this study was to investigate the effects of salinity, exposure duration and low-salt recovery solutions on seed germination of the weed Chenopodium acuminatum to get a clear insight about the germination strategy exhibited by this species in a saline habitat. Seeds were initially exposed to 0–400 mM NaCl for 10, 20 and 30 d. The subsequent recovery experiment was conducted differently. For those initially treated with 100 and 200 mM NaCl, the recovery solution was distilled water, while for those initially treated with 300 and 400 mM NaCl, the recovery solution was distilled water, at 50 and 100 mM NaCl. Results showed that the recovery germination percentage and rate significantly decreased when the exposure duration extended. Seeds could subsequently recover to germinate at high percentages at recovery salt solution concentrations for a short duration, but the recovery percentages and rates in high salinity, combined with high exposure duration and relatively high recovery salt concentrations, were remarkably lower. More than 30% of the ungerminated seeds were viable after the recovery experiment. We suggest that Ch. acuminatum exhibits a ‘cautious’ strategy of germination to avoid injury from long-term salt stress and ensure survival for the subsequent continuation of its population under unfavorable saline conditions.
Effect of Food Restriction on Food Grinding in Brandt’s Voles
Authors: Dai Xin , Han Yu-Xuan , Shen Qiu-Yi , Tang Hao , Cheng Li-Zhi , Yang Feng-Ping , Wei Wan-Hong , Yang Sheng-Mei
Published: November 2023

Food grinding is supposed to be influenced by multiple factors. However, how those factors affecting this behavior remain unclear. In this study, we investigated the effect of food restriction on food grinding in Brandt’s voles (Lasiopodomys brandtii), as well as the potential role of the gut microbiota in this process, through a comparison of the variations between voles with different food supplies. Food restriction reduced the relative amount of ground food to a greater extent than it lowered the relative food consumption, and altered the abundance of Staphylococcus, Aerococcus, Jeotgalicoccus, and Un--s-Clostridiaceae bacterium GM1. Fecal acetate content for the 7.5 g-food supply group was lower than that for the 15 g-food supply group. Our study indicated that food restriction could effectively inhibit food grinding. Further, Un--s-Clostridiaceae bacterium GM1 abundance, Aerococcus abundance, and acetate content were strongly related to food grinding. Variations in gut microbial abundance and short-chain fatty acid content induced by food restriction likely promote the inhibition of food grinding. These results could potentially provide guidance for reducing food waste during laboratory rodent maintenance.
Application of Gradient-Dependent Optimal Interpolation in Fishery Analysis of Neon Flying Squid (Ommastrephes bartramii) in the Kuroshio–Oyashio Confluence Region
Authors: Zhang Chunling , Cui Manman , Yu Wei , Liu Bilin
Published: November 2023

A key issue in fishery forecasting is the collection of high-precision subsurface environmental data. A data assimilation method, named gradient-dependent optimal interpolation, was used to construct the near-real-time vertical temperature and salinity structure of a squid fishery ground based on Argo observations. The results were verified by truth-finding comparisons and applied to analyze the relationship between neon flying squid and the subsurface environment in the Kuroshio–Oyashio Confluence Region. The temperature and salinity differences between the constructed results and survey data were less than ±0.5 °C and ±0.02, respectively. Most of the relative analysis errors were less than the observational errors. Statistical analysis revealed that the most suitable temperature for squid was 18–24 °C at the near-surface (<5 m), although the squid can endure a temperature range from 11 to 12 °C at a depth of 300 m. There was an obvious thermocline in the fishery ground, with a thermocline depth of 65 m and a mean strength of approximately 0.10 °C/m. The regressive relationship between vertical temperature (thermocline parameters) and squid catch per unit effort (CPUE) followed the exponential (Gaussian) function. The most suitable salinity was 33.0–34.2 at depths shallower than 300 m.
Bioaerosol Sensor for In Situ Measurement: Real-Time Measurement of Bioaerosol Particles in a Real Environment and Demonstration of the Effectiveness of Air Purifiers to Reduce Bioaerosol Particle Concentrations at Hot Spots
Authors: Yanagi U , Fukushima Nobuhiko , Nagai Hideyasu , Ye Haoyi , Kano Minoru
Published: November 2023

In this study, we first conducted laboratory experiments on the sensitivity of a newly developed bioaerosol sensor (BAS) suitable for in situ measurements. Then, we performed an in situ test in a shared student space at a university. Furthermore, the effectiveness of ventilation and air purification as a mitigation measure for a location with high concentrations of bioaerosol particles (hot spots) was verified. The experimental results show that the measured values for polystyrene latex are in good agreement with the predicted Mie theory value. They also show a good response to fluorescent particles. The in situ test showed that the BAS fluorescent system does not respond to non-fluorescent particles but only to fluorescent particles. During respiratory infection outbreaks, real-time detection at hot spots and a reduction in particulate matter, including bioaerosols, through ventilation and air purification equipment are effective. In this study, the BAS measurement results showed significant correlations not only with fluorescent particles but also with live bacteria. This does not prove that viruses can be measured in real time. If real-time measurements for viruses become available in the future, the findings of this study will be helpful in mitigating respiratory tract infections caused by viruses.
Caveolin-1: A Review of Intracellular Functions, Tissue-Specific Roles, and Epithelial Tight Junction Regulation
Authors: Dalton Cody M. , Schlegel Camille , Hunter Catherine J.
Published: November 2023

Caveolin-1 (Cav1) is a vital protein for many cellular processes and is involved in both the positive and negative regulation of these processes. Cav1 exists in multiple cellular compartments depending on its role. Of particular interest is its contribution to the formation of plasma membrane invaginations called caveolae and its involvement in cytoskeletal interactions, endocytosis, and cholesterol trafficking. Cav1 participates in stem cell differentiation as well as proliferation and cell death pathways, which is implicated in tumor growth and metastasis. Additionally, Cav1 has tissue-specific functions that are adapted to the requirements of the cells within those tissues. Its role has been described in adipose, lung, pancreatic, and vascular tissue and in epithelial barrier maintenance. In both the intestinal and the blood brain barriers, Cav1 has significant interactions with junctional complexes that manage barrier integrity. Tight junctions have a close relationship with Cav1 and this relationship affects both their level of expression and their location within the cell. The ubiquitous nature of Cav1 both within the cell and within specific tissues is what makes the protein important for ongoing research as it can assist in further understanding pathophysiologic processes and can potentially be a target for therapies.
Trace Amine-Associated Receptors and Monoamine-Mediated Regulation of Insulin Secretion in Pancreatic Islets
Authors: Vaganova Anastasia N. , Shemyakova Taisiia S. , Lenskaia Karina V. , Rodionov Roman N. , Steenblock Charlotte , Gainetdinov Raul R.
Published: November 2023

Currently, metabolic syndrome treatment includes predominantly pharmacological symptom relief and complex lifestyle changes. Trace amines and their receptor systems modulate signaling pathways of dopamine, norepinephrine, and serotonin, which are involved in the pathogenesis of this disorder. Trace amine-associated receptor 1 (TAAR1) is expressed in endocrine organs, and it was revealed that TAAR1 may regulate insulin secretion in pancreatic islet β-cells. For instance, accumulating data demonstrate the positive effect of TAAR1 agonists on the dynamics of metabolic syndrome progression and MetS-associated disease development. The role of other TAARs (TAAR2, TAAR5, TAAR6, TAAR8, and TAAR9) in the islet’s function is much less studied. In this review, we summarize the evidence of TAARs’ contribution to the metabolic syndrome pathogenesis and regulation of insulin secretion in pancreatic islets. Additionally, by the analysis of public transcriptomic data, we demonstrate that TAAR1 and other TAAR receptors are expressed in the pancreatic islets. We also explore associations between the expression of TAARs mRNA and other genes in studied samples and demonstrate the deregulation of TAARs’ functional associations in patients with metabolic diseases compared to healthy donors.
Mechanisms Underlying Rare Inherited Pediatric Retinal Vascular Diseases: FEVR, Norrie Disease, Persistent Fetal Vascular Syndrome
Authors: Le Vincent , Abdelmessih Gabrielle , Dailey Wendy A. , Pinnock Cecille , Jobczyk Victoria , Rashingkar Revati , Drenser Kimberly A. , Mitton Kenneth P.
Published: November 2023

Familial Exudative Vitreoretinopathy (FEVR), Norrie disease, and persistent fetal vascular syndrome (PFVS) are extremely rare retinopathies that are clinically distinct but are unified by abnormal retinal endothelial cell function, and subsequent irregular retinal vascular development and/or aberrant inner blood-retinal-barrier (iBRB) function. The early angiogenesis of the retina and its iBRB is a delicate process that is mediated by the canonical Norrin Wnt-signaling pathway in retinal endothelial cells. Pathogenic variants in genes that play key roles within this pathway, such as NDP, FZD4, TSPAN12, and LRP5, have been associated with the incidence of these retinal diseases. Recent efforts to further elucidate the etiology of these conditions have not only highlighted their multigenic nature but have also resulted in the discovery of pathological variants in additional genes such as CTNNB1, KIF11, and ZNF408, some of which operate outside of the Norrin Wnt-signaling pathway. Recent discoveries of FEVR-linked variants in two other Catenin genes (CTNND1, CTNNA1) and the Endoplasmic Reticulum Membrane Complex Subunit-1 gene (EMC1) suggest that we will continue to find additional genes that impact the neural retinal vasculature, especially in multi-syndromic conditions. The goal of this review is to briefly highlight the current understanding of the roles of their encoded proteins in retinal endothelial cells to understand the essential functional mechanisms that can be altered to cause these very rare pediatric retinal vascular diseases.