bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of Chronic Urticaria and Associated Conditions - A Web-Based Survey
Authors: Zysk Weronika , Trzeciak Magdalena
Published: February 2023

Introduction: Chronic urticaria is a common disease, characterized by the development of wheals, angioedema, or both, which can be associated with several comorbidities. Most of the available studies have focused on specific common comorbidities and their association with CU, but have seldom reported the overall burden of comorbidities.
Objectives: This study aimed to investigate and analyze self-reported comorbidities in polish patients with CU.
Methods: An anonymous online survey consisting of 20 questions was conducted on a members of Urticaria group on social media platform — Facebook. A total of 102 people took part in this survey. The results were analyzed in Microsoft Excel 2016.
Results: In the group 95.1% were females and 4.9% males, with a mean age of 33.8 years. The most common diagnosed type of urticaria was spontaneous (52.9%). Angioedema accompanied urticaria in 68.6% of the respondents, mainly those with delayed pressure urticaria (86.4%). 85.3% of respondents reported comorbidities, most often atopic diseases and allergies (49%), chronic inflammation and infections (36.3%), thyroid (36.3%) and psychiatric disorders (25.5%). Moreover, in 30.4% of patients at least one autoimmune disease was noted. As compared to the patients without autoimmune urticaria, much more with autoimmune urticaria had coexisting autoimmune disease (50% vs. 23.7%). The family history of autoimmune diseases was positive in 42.2%, and the familial history of urticaria and atopy was positive in 7.8% and 25.5%, respectively.
Conclusions: The knowledge of comorbidities of chronic urticaria may support clinicians to manage and treat patients with this common condition.
Dermoscopy of Onychomycosis: A Systematic Review
Authors: Litaiem Noureddine , Mnif Emna , Zeglaoui Faten
Published: February 2023

Introduction:
Onychomycosis represents a global burden accounting for about 50% of nail consultations. Several studies have tried to assess the dermoscopic features of onychomycosis. With the multiplication of papers, several “new” dermoscopic signs keep being added leading to some inconsistency in onychoscopic terminology.
Objective:
This study aimed to summarize the existing literature on the dermoscopic features of onychomycosis and propose a unified onychoscopic terminology.
Methods:
The literature search was performed using PubMed and Scopus databases up to October 30, 2021 to identify eligible contributions. In total, 33 records (2111 patients) were included.
Results:
The main dermoscopic signs of onychomycosis are “ruin appearance”, “longitudinal striae” and “spikes” on the proximal margin of onycholytic areas, with a specificity of 99.38%, 83.78%, and 85.64% respectively. The “aurora borealis” sign had the highest sensitivity and specificity.
Conclusions:
The current review provides a framework for issues related to the onychoscopic terminology of onychomycosis and is intended to serve as an aid for students, teachers, and researchers. We proposed a unifying terminology to describe dermoscopic signs of onychomycosis. Dermoscopic signs of onychomycosis show good specificity and are useful in distinguishing nail psoriasis, trauma, and onychomycosis. It helps differentiate fungal melanonychia from nail melanoma, nevi, and melanocytic activation.
DIFFERENT PSYCHOLOGICAL FEATURES BALLET ARTISTS FROM TEACHER-CHOREOGRAPHERS
Authors: Мацаренко Татьяна Николаевна
Published: February 2023

В статье представлены результаты исследования психологических особенностей артистов балета и педагогов-хореографов по методикам “Цель-Средство-Результат” А.А. Карманова, «Экспресс-диагностика уровня социальной фрустрированности» Л.И. Вассермана, возможность самореализации артистов балета после сценической карьеры. Рассмотрены требования педагогической деятельности, создание авторского проекта - стартапа.
TO THE QUESTION OF THE FORM AND POTENTIAL OF THE SUBJECT
Authors: Катульский Август Александрович
Published: February 2023

В работе рассмотрен вопрос о сути формы предмета, уменьшении потенциала предмета от взаимозависимости потенциалов элементов его содержания и изменениях структур потенциалов предмета в зависимости от выбора вида его формы.

The paper considers the question of the essence of the form of the object, the decrease in the potential of the object from the interdependence of the potentials of the elements of its content and changes in the structures of the potentials of the object, depending on the choice of the type of its form.
APPLICATION OF BANKRUPTSY MORATORIUM: GROUNDS, CONTENT AND CONSEQUENCES
Authors: Муталиева Аза Абукаровна
Published: February 2023

В настоящей статье автором рассмотрена такая мера государственного воздействия на предпринимательские отношения, как введение моратория на возбуждение дел о банкротстве, которая может быть рассмотрена, с одной стороны, как мера направленная на поддержку субъектов-должников, находящихся на стадии банкротства, с другой стороны, как мера, ограничивающая права кредиторов, связанные с возмещением убытков, причиненных неисполнением или ненадлежащим исполнением обязательств должниками.

In this article, the author considers such a measure of state influence on business relations as the introduction of a moratorium on the initiation of bankruptcy cases, which can be considered, on the one hand, as a measure aimed at supporting debtor entities at the stage of bankruptcy, on the other hand, as a measure limiting the rights of creditors related to damages caused by non-fulfillment or improper fulfillment of obligations by debtors.
THE COMPARISON OF THE ENVIRONMENTAL POLICY OF RUSSIA AND CHINA IN THE ARCTIC REGION
Authors: Веселова Дарья Николаевна
Published: February 2023

В статье определены основные интересы России и Китая в Арктике, сопоставлены мероприятия обеих стран по охране окружающей среды региона, изучена законодательная основа по проведению экологической политики России в ее арктической зоне и исследованы положения Белой книги по Арктической политике Китая, рассмотрены задачи политических акторов РФ и КНР, ответственных за проведение арктической политики.

The article defines the main interests of Russia and China in the Arctic, compares the activities of both countries to protect the environment of the region, studies the legislative basis for the environmental policy of Russia in its Arctic zone and explores the provisions of the White Paper on China's Arctic policy, are considers the tasks of political actors of the Russian Federation and China responsible for the implementation of the Arctic policy.
INDICATORS OF THE OPERATOR'S BRAIN ACTIVITY IN THE PROCESS OF INFLUENCING THE STATE OF CONSCIOUSNESS MIRRORS MG «MEGA-GALAXY»
Authors: Коекина Ольга Ивановна , Иванчук Сергей Викторович
Published: February 2023

Время - главная ценность в жизни человека.

Time is the main value in human life.
ORGANIZATION OF STUDENT SPORTS AT THE UNIVERSITY: EXPERIENCE AND CHALLENGES
Authors: Федотова Галина Александровна , Чистякова Елена Геннадьевна
Published: February 2023

В содержании статьи раскрываются ценностно-целевые ориентиры Концепции развития студенческого спорта в российских вузах. На основе анализа нормативно-правовой базы и существующего опыта деятельности студенческих спортивных организаций в университете подтверждается идея развития конкурентоспособности студентов - участников и организаторов массового студенческого движения. Выявлены проблемы, возникающие в процессе организации студенческого массового спортивного движения - недостаточное финансирование и отсутствие высококвалифицированного тренерского и преподавательского состава.

The content of the article reveals the value-target guidelines of the Concept of the development of student sports in Russian universities. Based on the analysis of the regulatory framework and the existing experience of student sports organizations at the university, the idea of developing the competitiveness of student participants and organizers of the mass student movement is confirmed. The problems arising in the process of organizing the student mass sports movement are identified - insufficient funding and lack of highly qualified coaching and teaching staff.
IMPACT OF A CHANGE IN LIMITS ON FOREIGN PROFESSIONAL PLAYERS COMPETING IN THE RUSSIAN PREMIER LEAGUE ON THE SALARIES OF RUSSIAN FOOTBALLERS
Authors: Фёдоров Юрий Владимирович , Гончарова Наталья Юрьевна
Published: February 2023

В статье раскрывается, что такое лимит на легионеров в РПЛ, как он связан с зарплатами российских игроков и их контрактами, а также рассмотрены возможные последствия его изменения с сезона 2020/2021.

The article shows what limits on foreign professional players competing in the Russian Premier League is, how it is connected with Russian Footballers’ Salaries ant their contracts. Possible consequences of it’s change from season 2020/2021 are considered.
INVESTIGATION OF NICOTINE OXIDATION REACTION IN THE FRAMEWORK OF FORMAL KINETICS ON THE EXAMPLE OF PIPE TOBACCO
Authors: Моисеев Игорь Викторович , Карманов Денис Александрович , Лёзный Валерий Владимирович
Published: February 2023

В работе представлены результаты исследований по изучению кинетики реакции окисления никотина, протекающего в процессе ферментации трубочного табака. Для получения кинетических зависимостей был проведен количественный анализ образцов табака на содержание никотина методом ВЭЖХ. Полученные данные позволили в рамках формальной кинетики описать реакцию его окисления, как реакцию второго порядка и определить вклад реагентов в скорость реакции.

The paper presents the results of studies on the kinetics of the nicotine oxidation reaction occurring during the fermentation of pipe tobacco. To obtain kinetic dependences, a quantitative analysis of tobacco samples for nicotine content was carried out by HPLC. The data obtained made it possible to describe the reaction of its oxidation as a second-order reaction within the framework of formal kinetics, and to determine the contribution of reagents to the reaction rate.
Реконструкция исторической памяти жителей Среднего Урала в конце XIX - начале XX века
Authors: Теленков Алексей Владимирович
Published: February 2023

Статья посвящена национальному самосознанию русских в конце ХIХ - начале ХХ века (по материалам Среднего Урала). Одной из ключевых основ национальной идентичности является историческая память, воззрения на прошлое, настоящее и взгляд в будущее. При этом важны факторы формирования памяти: традиционный и «современный» (концепция модернизации)
INTERPRITATION OF A INTERNATIONAL TREATY
Authors: Бикетова Янина Олеговна , Сафина Светлана Маратовна
Published: February 2023

В данной статье рассмотрена толкование международного договора, выяснение и разъяснение правильного смысла договора (его содержания) в целях наиболее правильного его применения и осуществления.

This article discusses the interpretation of an international treaty, the clarification and clarification of the correct meaning of the treaty (its content) in order to most correctly apply and implement it.
INTERNATIONAL LEGAL STATUS OF REFUGEES. FEATURES OF THE LEGAL STATUS OF A REFUGEE IN RUSSIA
Authors: Бикетова Янина Олеговна , Шайхилисламова Зиля Ирековна
Published: February 2023

В данной статье рассмотрены основные положения присвоения статуса беженца, международно-правовые положения, описаны основные права и обязанности сторон, а также представлены особенности присвоения статуса беженца в Российской Федерации.

This article discusses the main provisions of the assignment of refugee status, international legal provisions, describes the basic rights and obligations of the sides, and also presents the specifics of the assignment of refugee status in the Russian Federation.
ПОДХОДЫ К ЭКОНОМИКЕ НОВЫХ ПРОЕКТОВ МЕСТОРОЖДЕНИЙ НЕФТИ
Authors: Григорова Алина Дмитриевна , Егорова Татьяна Сергеевна , Привалов Николай Геннадьевич
Published: February 2023

В данной статье рассмотрен цикл оценки экономической эффективности проекта месторождения нефти, подходы и основные показатели экономической эффективности проекта. Сделан вывод о наиболее целесообразном подходе к экономической оценке проекта месторождения нефти.
ANODE MATERIALS IN LITHIUM-ION BATTERIES BASED ON TIN
Authors: Корбова Екатерина Вадимовна , Липкин Михаил Семенович , Чеснокова Елена Юрьевна , Сахадзе Татьяна Александровна
Published: February 2023

Новые материалы являются ключом к фундаментальным достижениям в области преобразования и хранения энергии, которые жизненно важны для решения проблемы глобального потепления и ограниченности ископаемого топлива. Композитные материалы рассмотренные в данной работе обладают уникальными комбинациями свойств в качестве электродов и электролитов в ряде энергетических устройств.

New materials are the key to fundamental advances in energy conversion and storage that are vital to addressing global warming and fossil fuel constraints. The composite materials discussed in this paper have unique combinations of properties as electrodes and electrolytes in a number of energy devices.
ИНВЕСТИЦИОННАЯ ПРИВЛЕКАТЕЛЬНОСТЬ ТРИС(ГИДРОКСИМЕТИЛ)ФОСФИНА?!
Authors: Греков Леонид Иванович
Published: February 2023

Трис(гидроксиметил)фосфин является практически значимым и перспективным продуктом. Однако согласно имеющимся доступным данным, в России исследования по его применению прекращены. Тем не менее создание современной, инновационной и экологически безопасной химической технологии получения трис(гидроксиметил)фосфина формирует перспективу дальнейшего использования и реализации проведенных научных исследований и разработок.
El uso polémico del Salmo 49, 16-20 en la controversia donatista: Optato y Agustín
Authors: D’Andrea Bruno ,   Order of Augustinian Recollects
Published: February 2023

En la controversia donatista la exégesis de algunos textos bíblicos constituyó el corazón de las discusiones. Los salmos, en particular, no dejaron de ser invocados para defender posiciones teológicas, especialmente las eclesiológicas. El artículo ofrece un estudio sobre el uso polémico del salmo 49 en escritos de Optato de Milevi y de Agustín de Hipona, no sin antes aludir brevemente a los antecedentes que encontramos en Cipriano de Cartago. El artículo presenta una visión panorámica de la exégesis católica del salmo 49 durante la controversia para mostrar las constantes temáticas que se presentan, así como una evolución en los acentos teológicos de dicha exégesis a partir de la producción antidonatista agustiniana.
Desde los ‘tabernacula pastorun’ martiriales hasta un ‘in meridie’ geográfico: La representación y refutación de la exégesis donatista de Cant 1, 6-7
Authors: Dupont Anthony - Dalvit, Matteo ,   Order of Augustinian Recollects
Published: February 2023

El artículo presenta una interpretación del texto de Cant 1, 6-7 en el contexto de la polémica antidonatista de Agustín. En la primera parte del artículo se toma en cuenta el sermo 46, para reconstruir la exégesis de Agustín sobre dicho texto, señalando otras explicaciones paralelas del mismo texto en diversas obras del Hiponate, para destacar, entre otras cosas, el status quaestionis de la presencia de este sermón en la Augustinus-Forschung. La segunda parte del artículo ofrece una posible lectura donatista del texto de Cant 1, 6-7. Se trata de una lectura diferente de la ofrecida por Agustín. El artículo presenta la hipótesis de que en el centro de la exegesis donatista de Cant 1, 6-7 se encontraba una lectura martirial del sintagma tabernacula pastorum, mientras que la interpretación agustiniana del sintagma in meridie estaría orientada hacia un sentido geográfico del mismo, desplazando la polémeica con los donatistas, en torno a la identidad de la Iglesia, de un contexto martirial a un contexto meramente geográfico
Notes on Polanyi’s 1954 Lecture, “Rules of Rightness”
Authors: Mullins Phil ,   The Polanyi Society
Published: February 2023

This short essay provides some historical notes helpful for understanding what Polanyi first called “rules of rightness” in his 1954 University of Chicago series of lecturess
What Is the Current Development Status of Character Education? Based on Seven Educators and Nearly Three Years of Literature Research
Authors: Zhang Lingmin
Published: February 2023

To have a deeper and more comprehensive understanding of the status quo of character education, to improve the citizens' character cultivation, and achieve better development of citizens, this paper has carried out a study on character education. This study uses the literature research method, experience summary method, and qualitative analysis method. First, it analyzes the ideas on character education by seven famous educators (Plato, Aristotle, Sukhomlinsky, Kohlberg, Albert Bandura, Bertrand Russell, and Thomas Lickona). Then, through Springer and CNKI (China National Knowledge Internet), we searched the academic literature on character education in 2020, 2021, and 2022. Understand the development process, the latest progress, and quality education problems by analyzing the current theoretical research results. The findings are as follows: in the current research on quality education, educators have put forward some relatively complete theories, but the actual effect may not be perfect; According to the three years of theoretical research, these results did not reasonably apply to the quality education practice. This research has theoretical and practical significance for the future development of character education and for improving the academic system of quality education.
Pancreatic Stones in Children with Chronic Pancreatitis: A Case Report
Authors: Nicodemus Nicodemus , Susanti Nuraini Irma
Published: February 2023

Background: Chronic pancreatitis is a continuous progressive inflammation of the pancreas that can cause recurrent abdominal pain. The incidence of chronic pancreatitis in children is on an upward trend in recent years. The purpose of this case report is to enhance clinician's insight in considering chronic pancreatitis as a differential diagnosis in cases of recurrent abdominal pain in children.
Case: We reported a case of chronic pancreatitis with pancreatic stones in a 12-year-old child. The patient came with complaints of recurrent upper left abdominal and heartburn accompanied by nausea and vomiting. Epigastric and left hypochondriac tenderness were found. Laboratory examination showed an increase in pancreatic enzymes up to 6x the normal value. The results of abdominal CT-scan and MRCP showed multiple pancreatic stones with pseudocysts. The patient then underwent the Puestow procedure. Postoperatively, the complaints of abdominal pain resolved and the pancreatic enzymes improved significantly.
Discussion: The diagnosis of pancreatitis must meet 2 out of the 3 criteria that have been determined. Primary management includes fluids, analgesics, early nutrition, and surgery in cases of chronic pancreatitis accompanied by complications such as pseudocysts or pancreatic stones.
Conclusion: This case teaches the need for a careful clinical approach and consideration of chronic pancreatitis as a differential diagnosis in a child with recurrent abdominal pain.
Penghijauan Dalam Rangka Mengurangi Dampak Pemasanan Global Di Bidang Pertanian Di Jorong Pakan Baru Nagari Taram
Authors: Husnarti Husnarti , Rahmawati Rahmawati , Ernanda Revi , Akbar Yustitia , Desriana Desriana , Sabri Yunita
Published: February 2023

Pemamasan global merupakan tantangan yang dihadapi bidang pertanian karena pemanasan global mengakibatkan penurunan produksi dan produktivitas tanaman pangan yang diakibatkan oleh bencana alam salah satunya adalah banjir. Nagari Taram yang merupakan penghasil tanaman pangan terutama padi di Kecamatan Harau merupakan wilayah yang rawan bencana banjir. Sehingga ketika daerah ini dilanda banjir akan menyebabkan penurunan produksi padi. Oleh sebab itu perlu dilakukan penghijauan sebagai strategi penanggulangan banjir jangka panjang. Penghijaun tersebut dilakukan di daerah aliran sungai Kapalo Banda. Tanaman yang ditanam adalah pohon ketapang karena pohon ketapang merupakan pohon yang memberikan banyak manfaat seperti sebagai peneduh, menetralkan ph air, bijinya dikonsumsi, sebagai material bangunan dan yang paling penting ektraksnya bisa digunakan petani untuk herbisida. Penghijauan ini diharapkan akan memberi pengetahuan, contoh dan motivasi untuk masyarakat setempat sehingga nantinya penghijuan ini akan berlanjut ke bagian hilir sungai Kapalo Banda
ChatGPT: Exploring the Role of Cybersecurity in the Protection of Medical Information
Authors: Mijwil Maad , Mohammad Aljanabi  , Ahmed Hussein Ali
Published: February 2023

ChatGPT is a large language model developed by OpenAI. It is trained on a dataset of conversational text and can be used to generate human-like responses to prompts in a variety of languages and formats. It can be used for tasks such as chatbots, language translation, and text completion. The role of ChatGPT is to generate human-like text based on a given prompt or context. It can be used in a variety of applications such as chatbots, language translation, text completion, and question answering. Additionally, it can be fine-tuned for specific tasks such as generating product descriptions or summarizing articles. It can also be used to generate creative writing such as poetry and stories. It can be integrated into a wide range of industries from customer service to entertainment, to research.
The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy
Authors: Lee Jin Soo , Lee Ji Sung , Gwag Byoung Joo , Choi Dennis W. , An Chun San , Kang Hyun Goo , Song Tae-Jin , Ahn Seong Hwan , Kim Chang Hun , Shin Dong-Ick , Kwon Sun U.
Published: February 2023

Background and Purpose Nelonemdaz (Neu2000) has both selective antagonism against 2B subunit of N-methyl-D-aspartate receptor and antioxidant activity. This drug provides sufficient evidence of neuroprotection in acute cerebral ischemia/reperfusion models. This phase III trial aims to determine this effect in patients.Design The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz is a multicenter, double-blinded clinical trial. A total of 496 patients will be randomly assigned into the nelonemdaz (a total of 5,250 mg divided by 10 times for 5 days) and placebo groups. Patients will be included if they have an acute ischemic stroke (National Institutes of Health Stroke Scale score ≥8) caused by intracranial large vessel occlusion in the anterior circulation (Alberta Stroke Program Early CT Score ≥4), and if they are expected to undergo endovascular thrombectomy within 12 hours after stroke onset.Endpoints The primary endpoint is a favorable shift in the modified Rankin Scale (mRS) score at 90 days after the first dose of drug. The data will be analyzed by the Cochran–Mantel–Haenszel shift test. The secondary endpoints include functional independence (mRS 0–2) at 35 and 90 days, the favorable shift of mRS at 35 days, the proportion of mRS 0 at 35 and 90 days, and the occurrence rates of symptomatic intracranial hemorrhage within 7 days.Conclusion This trial will clarify the efficacy and safety of nelonemdaz in patients with acute ischemic stroke and endovascular thrombectomy. This study has been registered at ClinicalTrials. gov (NCT05041010).
Perilaku Remaja Awal yang Mengalami Sibling Rivalry dalam Keluarga di Kanagarian Koto Baru III Jorong
Authors: Anggraini Putri Nadila , Rahmi Alfi
Published: February 2023

Aggressive behavior of early adolescents who experience sibling rivalry can grow in families with more than one child as stated by Bakwin H that sibling competition is more intense in small families (families with fewer children) compared to families with many children. . The aim is to find out the behavior of early adolescents who experience sibling rivalry in the family at Kanagarian Koto Baru III, Jorong. The research method is descriptive qualitative, key informants are 5 early adolescents who experience sibling rivalry and supporting informants 5 parents of early adolescents who experience sibling rivalry in the family. Data collection techniques through observation and interviews. Data analysis techniques with data reduction, data display, and data verification. The validity of the data used with data triangulation with source triangulation. The results of the study: 1) Verbal is a form of negative behavior in the form of words or verbally with the aim of hurting the victim (ridicule, insult, and yell). 2) Physical is a form of negative behavior in the form of physical assault aimed at injuring, harming, injuring, or damaging other people's objects (hitting, kicking, pushing, biting, and throwing), 3) Expression of anger is a form of behavior that its nature is hidden in the feelings of other people but the effect can be seen in actions that hurt other people (anger and annoyance). 4) Hostility is an invisible behavior, namely negative attitudes or feelings towards other people (jealousy and envy).
Pemberian Pelayanan yang Tepat dan Saluran Komunikasi yang Efektif dalam Pendidikan Agama Islam Jarak Jauh Dirancang dengan Mempertimbangkan Konteks Sosial Budaya Turki
Authors: Haqi Arie Adrian
Published: February 2023

Understanding the socio-cultural context is key to developing the right support system for distance learners. The socio-cultural context in Turkey is an important element in the development of Turkish distance education programs, where the two elements of Turkish cultural patronage and oral tradition - seem to play an important role. The main objective of this study was to determine the role of the socio-cultural context in designing appropriate support services and improving interaction in the Turkish Distance Education System, namely, the Faculty of Open Education (OEF). The study first introduces the OEF technology and socio-cultural context then presents to consider the influence of those contexts in designing appropriate support services and enhancing interactions; and finally provide several suggestions to improve student support and interaction in accordance with the prevailing socio-cultural context
The Soft Power of the United States Foreign Policy Towards the Middle East 2011-2021 a case study (Jordan & Egypt)
Authors: Bani Salama Muhammad , Al-Masadeh Rasmi
Published: February 2023

The purpose of this study was to identify the soft power of US foreign policy toward the Middle East region through a study of the cases of Jordan and Egypt, as well as to analyze the tools used by the US to enhance its ability to preserve its vital interests in the Middle East. The study took an analytical-descriptive approach in gathering information about soft power, such as the foundations, components, and strategies employed by the United States of America in the Middle East region. The case study approach will focus on the soft power of US foreign policy in Jordan and Egypt as two special cases, and will then discuss, describe, and analyze the policy's goals and strategies. The researcher will also use a comparative approach to demonstrate the differences in soft power used in Jordan and Egypt, as well as the impact and outcomes of each on the two Middle Eastern countries. The study revealed numerous findings, the most notable of which was that the United States followed a policy of loans, aid, and grants, allowing it to impose its conditions on the country receiving the aid. The geopolitical burdens of both the Jordanian and Egyptian states were the primary factors in the two countries' orientation toward this aid and acceptance of the United States' cultural, technical, and other programs. The Jordanian and Egyptian economies' weaknesses, limitations, and heavy reliance on the service sector, as well as their limited domestic product and high rates of poverty and unemployment, drove the response to soft power tools such as financial aid, economic, technical, and cultural programs, and scientific exchange, implying that the two countries are closely linked with the United States and international and regional coordination. ​ Keywords: soft power, American foreign policy, the Middle East, Jordan, Egypt.
A novel metaheuristic prediction approach for COVID-19 cases using XGBoost algorithm
Authors: Gopatoti Anandbabu
Published: February 2023

COVID-19 prediction is of great importance to build stronger government prevention and control of the global pandemic. This pandemic has a devastating impact on people and their lives. Many industries are suffering and are struggling to overcome unexpected pandemic challenges. Therefore, it is extremely important to develop up to date and practicable models for time series prediction of COVID-19 that would give promising results. In this paper, we build a model for predicting daily confirmed n w cases for the time series data of Europe by applying the Extreme Gradient Boosting (XGBoost) algorithm and using two performance parameters such as RMSE and MAPE to evaluate the effect of model fitting. Since machine learning methods (ML) have shown favorable results recently, among the tested models, XGBoost has shown to give the best results among the other models tested. Another advantage of the model is that we can use the XGBoost model to determine the robustness of the predictive model by adjusting parameter features. Our results are in line with the expectations of the performance of the model based on the available data and the variability of the data. By analyzing important features and updating the prediction for the new cases of the pandemic, the governments all around the globe could manage the situation much more effortlessly and with greater impact.
The Impact of the Energy Crisis on the Economic Parameters of the Western Balkans
Authors: Saliu Fluturim , Deari Hasim
Published: February 2023

World fuel crisis, rising prices, global warming and climate changes are influencing all of the world economies. Small countries like in the Western Balkans that have open economies are also feeling the impacts of these events. The energy crisis has reflected all the economic parameters in all the economies worldwide. Evidently that as soon as someone thinks that one crisis is overcome, there is another wave that strikes even harder and makes the whole situation even worse than expected. At first there was the COVID-19 pandemic, where the economy had the first touch of the bottom, then the Russian invasion over Ukraine that grew in warzone and the economy of the Western Balkans countries hit the bottom again. As it was not enough, the prices of emergences are sky hi and the economies of these countries have to take even that burden and again hit the bottom as hard as it can hit.
Contribution à une lecture praxéologique du leadership entrepreneurial de crise des dirigeantes de PME : l’exemple de la crise sanitaire de la Covid-19
Authors: Pailot Philippe , Chasserio Stéphanie , Lebègue Typhaine , Poroli Corinne
Published: February 2023

La crise pandémique de la Covid-19 a constitué une situation adverse pour tous les acteurs du monde économique. En mobilisant le concept de leadership entrepreneurial, cet article vise à analyser les actions organisationnelles et les postures de leadership adoptées par des dirigeantes expérimentées pour garantir la continuité de leur activité économique, voire assurer la survie de leur entreprise. Nous chercherons à montrer que leurs actions et pratiques ne sont pas univoques. Elles se caractérisent, au contraire, par une forme de contingence traversée par des champs de tension et un subtil équilibre entre décisions stratégiques d’exploitation et d’exploration et une mise en oeuvre stratégique reposant tant sur des processus opératoires que relationnels. En filigrane, ce travail de recherche nous permettra de saisir les contours d’une forme singulière de leadership entrepreneurial lié aux situations de crise. Nous questionnerons également les limites de l’usage de la notion de genre pour appréhender les comportements entrepreneuriaux et les processus de décision déployés par les entrepreneures dans des contextes d’adversité.
Croyances des dirigeants concernant les retombées du développement des compétences : effet modérateur sur les liens entre exigences perçues du travail et dépenses déclarées de formation dans les PME québécoises
Authors: Foucher Roland , Ben Mansour Jamal , Michaud Renée , Morin Denis
Published: February 2023

Cette recherche vise à améliorer la compréhension de l’investissement en formation dans les PME en vérifiant empiriquement s’il reflète l’ampleur des exigences du travail et, en corollaire, si les croyances des dirigeants concernant les retombées du développement des compétences modèrent l’effet des exigences du travail, que l’entreprise soit soumise ou non à l’obligation légale d’investir en formation. Le choix de caractéristiques touchant l’organisation (exigences cognitives et relationnelles du travail), le dirigeant (croyances) et l’environnement (législation) s’inscrit dans une approche systémique et se fonde sur des écrits touchant les besoins d’apprentissage et l’influence des dirigeants de PME.

Les données ont été collectées par questionnaire auprès de 287 dirigeants de PME québécoises. Trois résultats ressortent des régressions logistiques : les exigences du travail perçues par les dirigeants de PME interrogés influencent le niveau d’investissement en formation déclaré par leur entreprise ; leur croyance dans l’utilité du développement des compétences augmente l’influence des exigences du travail sur le niveau d’investissement, que l’entreprise soit soumise ou non à l’obligation légale de consacrer à la formation une somme minimale, le lien entre les exigences du travail et l’investissement en formation persiste malgré les craintes des dirigeants concernant les impacts négatifs du développement des compétences.
Propagation characteristics of bright and mixed solitons based on the variable coefficient (3+1)-dimensional cubic-quintic complex Ginzburg-Landau equation
Authors: Yang Jia-Qi , Liu Wen-Jun ,   School of Science, Beijing University of Posts and Telecommunications, Beijing 100876, China
Published: February 2023

In the study of telecommunication system, the variable coefficient (3+1)-dimensional cubic-quintic complex Ginzburg-Landau equation is used as the optical solitons transmission model, which not only explains the physical meaning of the existing model with quintic terms, but also has more nonlinear dynamics characteristics of the higher dimensional system than the lower dimensional system. In this paper, the analytical soliton solutions of the (3+1)-dimensional cubic-quintic CGL equations with variable coefficients are obtained by using the modified Hirota method. By selecting certain parameters of the nonlinear coefficients and spectral filtering terms, a special kind of mixed soliton solution is obtained, which has the characteristics of bright soliton, dark soliton and kinked soliton at the same time. Subsequently, the influence of changing the nonlinear, spectral filtering, linear loss parameters and other parameters on the transmission characteristics of solitons is discussed respectively, so as to realize the control of optical solitons, which can not only control the propagation of optical solitons in different forms, but also can realize the adjustment of the amplitude and pulse width of the pulse and control the propagation direction and energy of the pulse for the mixed solitons of a particular form. The research results of high dimensional CGL system in this paper can be applied to nonlinear optical system, ultra-fast optical digital logic system and other different experiments and application fields.
Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis
Authors: Du Chunxiu , Xu Hu , Cao Cong , Cao Jiahui , Zhang Yufei , Zhang Cong , Qiao Rongfang , Ming Wenhua , Li Yaqing , Ren Huiwen , Cui Xiaohui , Luan Zhilin , Guan Youfei , Zhang Xiaoyan
Published: February 2023

Hyperosmolarity of the renal medulla is essential for urine concentration and water homeostasis. However, how renal medullary collecting duct (MCD) cells survive and function under harsh hyperosmotic stress remains unclear. Using RNA-Seq, we identified SLC38A2 as a novel osmoresponsive neutral amino acid transporter in MCD cells. Hyperosmotic stress-induced cell death in MCD cells occurred mainly via ferroptosis, and it was significantly attenuated by SLC38A2 overexpression but worsened by Slc38a2-gene deletion or silencing. Mechanistic studies revealed that the osmoprotective effect of SLC38A2 is dependent on the activation of mTORC1. Moreover, an in vivo study demonstrated that Slc38a2-knockout mice exhibited significantly increased medullary ferroptosis following water restriction. Collectively, these findings reveal that Slc38a2 is an important osmoresponsive gene in the renal medulla and provide novel insights into the critical role of SLC38A2 in protecting MCD cells from hyperosmolarity-induced ferroptosis via the mTORC1 signalling pathway.
Evidence for dopaminergic involvement in endogenous modulation of pain relief
Authors: Desch Simon , Schweinhardt Petra , Seymour Ben , Flor Herta , Becker Susanne
Published: February 2023

Relief of ongoing pain is a potent motivator of behavior, directing actions to escape from or reduce potentially harmful stimuli. Whereas endogenous modulation of pain events is well characterized, relatively little is known about the modulation of pain relief and its corresponding neurochemical basis. Here, we studied pain modulation during a probabilistic relief-seeking task (a ‘wheel of fortune’ gambling task), in which people actively or passively received reduction of a tonic thermal pain stimulus. We found that relief perception was enhanced by active decisions and unpredictability, and greater in high novelty-seeking trait individuals, consistent with a model in which relief is tuned by its informational content. We then probed the roles of dopaminergic and opioidergic signaling, both of which are implicated in relief processing, by embedding the task in a double-blinded cross-over design with administration of the dopamine precursor levodopa and the opioid receptor antagonist naltrexone. We found that levodopa enhanced each of these information-specific aspects of relief modulation but no significant effects of the opioidergic manipulation. These results show that dopaminergic signaling has a key role in modulating the perception of pain relief to optimize motivation and behavior.
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion
Authors: Mann Jake P , Duan Xiaowen , Patel Satish , Tábara Luis Carlos , Scurria Fabio , Alvarez-Guaita Anna , Haider Afreen , Luijten Ineke , Page Matthew , Protasoni Margherita , Lim Koini , Virtue Sam , O'Rahilly Stephen , Armstrong Martin , Prudent Julien , Semple Robert K , Savage David B
Published: February 2023

Mitochondrial dysfunction has been reported in obesity and insulin resistance, but primary genetic mitochondrial dysfunction is generally not associated with these, arguing against a straightforward causal relationship. A rare exception, recently identified in humans, is a syndrome of lower body adipose loss, leptin-deficient severe upper body adipose overgrowth, and insulin resistance caused by the p.Arg707Trp mutation in MFN2, encoding mitofusin 2. How the resulting selective form of mitochondrial dysfunction leads to tissue- and adipose depot-specific growth abnormalities and systemic biochemical perturbation is unknown. To address this, Mfn2R707W/R707W knock-in mice were generated and phenotyped on chow and high fat diets. Electron microscopy revealed adipose-specific mitochondrial morphological abnormalities. Oxidative phosphorylation measured in isolated mitochondria was unperturbed, but the cellular integrated stress response was activated in adipose tissue. Fat mass and distribution, body weight, and systemic glucose and lipid metabolism were unchanged, however serum leptin and adiponectin concentrations, and their secretion from adipose explants were reduced. Pharmacological induction of the integrated stress response in wild-type adipocytes also reduced secretion of leptin and adiponectin, suggesting an explanation for the in vivo findings. These data suggest that the p.Arg707Trp MFN2 mutation selectively perturbs mitochondrial morphology and activates the integrated stress response in adipose tissue. In mice, this does not disrupt most adipocyte functions or systemic metabolism, whereas in humans it is associated with pathological adipose remodelling and metabolic disease. In both species, disproportionate effects on leptin secretion may relate to cell autonomous induction of the integrated stress response.
Development of a novel mathematical model that explains SARS-CoV-2 infection dynamics in Caco-2 cells
Authors: Staroverov Vladimir , Nersisyan Stepan , Galatenko Alexei , Alekseev Dmitriy , Lukashevich Sofya , Polyakov Fedor , Anisimov Nikita , Tonevitsky Alexander
Published: February 2023

Mathematical modeling is widely used to study within-host viral dynamics. However, to the best of our knowledge, for the case of SARS-CoV-2 such analyses were mainly conducted with the use of viral load data and for the wild type (WT) variant of the virus. In addition, only few studies analyzed models for in vitro data, which are less noisy and more reproducible. In this work we collected multiple data types for SARS-CoV-2-infected Caco-2 cell lines, including infectious virus titers, measurements of intracellular viral RNA, cell viability data and percentage of infected cells for the WT and Delta variants. We showed that standard models cannot explain some key observations given the absence of cytopathic effect in human cell lines. We propose a novel mathematical model for in vitro SARS-CoV-2 dynamics, which included explicit modeling of intracellular events such as exhaustion of cellular resources required for virus production. The model also explicitly considers innate immune response. The proposed model accurately explained experimental data. Attenuated replication of the Delta variant in Caco-2 cells could be explained by our model on the basis of just two parameters: decreased cell entry rate and increased cytokine production rate.
Julgamento e tomada de decisão de contadores no Setor Público
Authors: Pacheco Ezequiel Nunes , Kronbauer Clovis Antonio , Ott Ernani , Dantas Vilmar Secundina
Published: February 2023

Esta pesquisa teve o objetivo de analisar como o Julgamento e Tomada de Decisão dos contadores em entidades do setor público é influenciado por aspectos do indivíduo, da tarefa e as pressões institucionais na implementação de normas relacionadas aos procedimentos de incorporação, depreciação e baixa de bens móveis e imóveis. A pesquisa se caracteriza como qualitativa e descritiva. Foram realizados dois grupos focais e 20 entrevistas com contadores que atuam em entidades do setor público da esfera municipal, estadual e federal, considerando como temáticas os aspectos do indivíduo, da tarefa e pressões institucionais. Os dados dessa pesquisa foram analisados com auxílio do software on-line happyscribe e do software IRAMUTEC. Após o agrupando em categorias conforme os pressupostos teóricos da Teoria Institucional e da Racionalidade Limitada, utilizou-se o método da nuvem de palavras e a análise de similitude, que agrupa as palavras e as organiza graficamente em função da sua frequência. Os resultados apontaram como influencia o conhecimento e experiência; forma de apresentação, complexidade e risco; e as pressões institucionais coercitivas, normativa e mimética no JDM dos contadores na implementação dos procedimentos de incorporação, depreciação e baixa de bens móveis.
MODELOWANIE I ANALIZA PŁYNIĘCIA MATERIAŁU ROZDROBNIONEGO PODCZAS ŚCINANIA W REOMETRZE PIERŚCIENIOWYM Z WYKORZYSTANIEM METODY ELEMENTÓW DYSKRETNYCH
Authors:   Rzeszow University of Technology, Faculty of Chemistry, Department of Chemical and Process Engineering, Chutkowski Marcin , Zapała Wojciech , Przywara Mateusz
Published: February 2023

Due to the fact that Jenike's cell has been designed and used for testing powder materials under load of hundreds of kPa, characteristic for large-tonnage processes, it is an inappropriate tool for testing materials under load conditions well below 10 kPa. As an alternative, an annular cell rheometer test constructed in such a way that the shear band covers the entire volume of material tested is proposed. After the experimental tests, a computer simulation of powder shearing, based on the discrete Element Method (DEM), was used to analyze timespatial distributions of experimentally unmeasurable physical properties of the powder bed. The simulation results proved that the shearing band covers entire rheometer gap.
LASER GENERATED GOLD NANOPARTICLES FOR MASS SPECTROMETRY OF LOW MOLECULAR WEIGHT COMPOUNDS
Authors:   Rzeszow University of Technology, Faculty of Chemistry, Department of Inorganic and Analytical Chemistry, Płaza-Altamer Aneta , Kołodziej Artur , Nizioł Joanna , Ruman Tomasz
Published: February 2023

Preparation of gold nanoparticles (AuNPs) by pulsed fiber laser (PFL) laser generated nanomaterial (LGN) with the use of 2D galvo-scanner (2D GS) is described. The procedure of covering of custom-made stainless steel MALDI targets containing studied objects via nebulization is also presented. Examples of application of new method (PFL-2D GS LGN and nebulization) in laser desorption/ionization mass spectrometry (LDI MS) analyses are shown. These include tests with amino acids and also low molecular weight polymer.
An Ethnobotanical Study to Document the Indigenous Knowledge of Buksa Tribe of Uttarakhand, India
Authors: Kumar Meenish , Rajpoot Ankita , Rajput Raksha , Sharma Jokhan , Kumar Uttam , Kouser Mushtaque , Kumar Ved Prakash
Published: February 2023

The present paper aimed at reporting the traditional indigenous knowledge related to the preparation of medicines by a primitive tribe of Uttarakhand i.e., the Buksa tribe. In this study 109 plant species were recorded which belongs to 53 families. The Buksa tribe uses the plant to prepare the medicines in order to cure many diseases. Herbs are most used plant type. It has been noticed that leaves are most used part of the plant for the preparation of medicines by the tribe. The Family Fabaceae (18%) followed by Malvaceae and Moraceae (13% each) and Apocynaceae (11%) were the dominant family of plants used by the tribe. It has been noticed that the knowledge related to the ethnobotany is only bound to the old agers. The young generation is lacking this knowledge. Buksas are used to be the best medical healers but passing of knowledge from one generation to other generation is decreasing. Their indigenous knowledge of preparing the medicine is also not documented earlier by them. The traditional knowledge which passes from one generation to another verbally is now in a disappearing state. Thus, it is the need of the hour to document the precious knowledge which can be used by the future generations.