bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Gut Bacterial Communities of Fall Armyworm (Spodoptera frugiperda) Reared on Different Host Plants
Authors: Lv Dongbiao , Liu Xueying , Dong Yanlu , Yan Zizheng , Zhang Xuan , Wang Ping , Yuan Xiangqun , Li Yiping
Published: October 2021

Spodoptera frugiperda is a highly polyphagous and invasive agricultural pest that can harm more than 300 plants and cause huge economic losses to crops. Symbiotic bacteria play an important role in the host biology and ecology of herbivores, and have a wide range of effects on host growth and adaptation. In this study, high-throughput sequencing technology was used to investigate the effects of different hosts (corn, wild oat, oilseed rape, pepper, and artificial diet) on gut microbial community structure and diversity. Corn is one of the most favored plants of S. frugiperda. We compared the gut microbiota on corn with and without a seed coating agent. The results showed that Firmicutes and Bacteroidetes dominated the gut microbial community. The microbial abundance on oilseed rape was the highest, the microbial diversity on wild oat was the lowest, and the microbial diversity on corn without a seed coating agent was significantly higher than that with such an agent. PCoA analysis showed that there were significant differences in the gut microbial community among different hosts. PICRUSt analysis showed that most of the functional prediction categories were related to metabolic and cellular processes. The results showed that the gut microbial community of S. frugiperda was affected not only by the host species, but also by different host treatments, which played an important role in host adaptation. It is important to deepen our understanding of the symbiotic relationships between invasive organisms and microorganisms. The study of the adaptability of host insects contributes to the development of more effective and environmentally friendly pest management strategies.
Nuclear mRNA Quality Control and Cytoplasmic NMD Are Linked by the Guard Proteins Gbp2 and Hrb1
Authors: Lu Yen-Yun , Krebber Heike
Published: October 2021

Pre-mRNA splicing is critical for cells, as defects in this process can lead to altered open reading frames and defective proteins, potentially causing neurodegenerative diseases and cancer. Introns are removed in the nucleus and splicing is documented by the addition of exon-junction-complexes (EJCs) at exon-exon boundaries. This “memory” of splicing events is important for the ribosome, which translates the RNAs in the cytoplasm. In case a stop codon was detected before an EJC, translation is blocked and the RNA is eliminated by the nonsense-mediated decay (NMD). In the model organism Saccharomyces cerevisiae, two guard proteins, Gbp2 and Hrb1, have been identified as nuclear quality control factors for splicing. In their absence, intron-containing mRNAs leak into the cytoplasm. Their presence retains transcripts until the process is completed and they release the mRNAs by recruitment of the export factor Mex67. On transcripts that experience splicing problems, these guard proteins recruit the nuclear RNA degradation machinery. Interestingly, they continue their quality control function on exported transcripts. They support NMD by inhibiting translation and recruiting the cytoplasmic degradation factors. In this way, they link the nuclear and cytoplasmic quality control systems. These discoveries are also intriguing for humans, as homologues of these guard proteins are present also in multicellular organisms. Here, we provide an overview of the quality control mechanisms of pre-mRNA splicing, and present Gbp2 and Hrb1, as well as their human counterparts, as important players in these pathways.
Peimine, an Anti-Inflammatory Compound from Chinese Herbal Extracts, Modulates Muscle-Type Nicotinic Receptors
Authors: Alberola-Die Armando , Encinar José Antonio , Cobo Raúl , Fernández-Ballester Gregorio , González-Ros José Manuel , Ivorra Isabel , Morales Andrés
Published: October 2021

Fritillaria bulbs are used in Traditional Chinese Medicine to treat several illnesses. Peimine (Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage-dependent ion channels and muscarinic receptors, but its interaction with ligand-gated ion channels remains unexplored. We have studied if Pm affects nicotinic acetylcholine receptors (nAChRs), since they play broad functional roles, both in the nervous system and non-neuronal tissues. Muscle-type nAChRs were incorporated to Xenopus oocytes and the action of Pm on the membrane currents elicited by ACh (IAChs) was assessed. Functional studies were combined with virtual docking and molecular dynamics assays. Co-application of ACh and Pm reversibly blocked IACh, with an IC50 in the low micromolar range. Pm inhibited nAChR by: (i) open-channel blockade, evidenced by the voltage-dependent inhibition of IAch, (ii) enhancement of nAChR desensitization, revealed by both an accelerated IACh decay and a decelerated IACh deactivation, and (iii) resting-nAChR blockade, deduced from the IACh inhibition elicited by Pm when applied before ACh superfusion. In good concordance, virtual docking and molecular dynamics assays demonstrated that Pm binds to different sites at the nAChR, mostly at the transmembrane domain. Thus, Pm from Fritillaria bulbs, considered therapeutic herbs, targets nAChRs with high affinity, which might account for its anti-inflammatory actions.
EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors
Authors: Souza Barbara Kunzler , Freire Natalia Hogetop , Jaeger Mariane , de Farias Caroline Brunetto , Brunetto Algemir L. , Brunetto André T. , Roesler Rafael
Published: October 2021

Epigenetic mechanisms, including post-translational modifications of DNA and histones that influence chromatin structure, regulate gene expression during normal development and are also involved in carcinogenesis and cancer progression. The histone methyltransferase G9a (euchromatic histone lysine methyltransferase 2, EHMT2), which mostly mediates mono- and dimethylation by histone H3 lysine 9 (H3K9), influences gene expression involved in embryonic development and tissue differentiation. Overexpression of G9a has been observed in several cancer types, and different classes of G9a inhibitors have been developed as potential anticancer agents. Here, we review the emerging evidence suggesting the involvement of changes in G9a activity in brain tumors, namely glioblastoma (GBM), the main type of primary malignant brain cancer in adults, and medulloblastoma (MB), the most common type of malignant brain cancer in children. We also discuss the role of G9a in neuroblastoma (NB) and the drug development of G9a inhibitors.
ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype
Authors: Sheldon Helen , Alexander John , Bridges Esther , Moreira Lucia , Reilly Svetlana , Ang Koon Hwee , Wang Dian , Lin Salwa , Haider Syed , Banham Alison H. , Harris Adrian L.
Published: October 2021

ELTD1 is expressed in endothelial and vascular smooth muscle cells and has a role in angiogenesis. It has been classified as an adhesion GPCR, but as yet, no ligand has been identified and its function remains unknown. To establish its role, ELTD1 was overexpressed in endothelial cells. Expression and consequently ligand independent activation of ELTD1 results in endothelial-mesenchymal transistion (EndMT) with a loss of cell-cell contact, formation of stress fibres and mature focal adhesions and an increased expression of smooth muscle actin. The effect was pro-angiogenic, increasing Matrigel network formation and endothelial sprouting. RNA-Seq analysis after the cells had undergone EndMT revealed large increases in chemokines and cytokines involved in regulating immune response. Gene set enrichment analysis of the data identified a number of pathways involved in myofibroblast biology suggesting that the endothelial cells had undergone a type II EMT. This type of EMT is involved in wound repair and is closely associated with inflammation implicating ELTD1 in these processes.
Light Tailoring: Impact of UV-C Irradiation on Biosynthesis, Physiognomies, and Clinical Activities of Morus macroura-Mediated Monometallic (Ag and ZnO) and Bimetallic (Ag–ZnO) Nanoparticles
Authors: Anjum Sumaira , Khan Amna , Qamar Anza , Fatima Noor , Drouet Samantha , Renouard Sullivan , Blondeau Jean , Abbasi Bilal , Hano Christophe
Published: October 2021

A nano-revolution based on the green synthesis of nanomaterials could affect all areas of human life, and nanotechnology represents a propitious platform for various biomedical applications. During the synthesis of nanoparticles, various factors can control their physiognomies and clinical activities. Light is one of the major physical factors that can play an important role in tuning/refining the properties of nanoparticles. In this study, biocompatible monometallic (AgNPs and ZnONPs) and bimetallic Ag–ZnONPs (0.1/0.1 and 0.1/0.5) were synthesized under UV-C light irradiation from the leaf extract of Morus macroura, which possesses enriched TPC (4.238 ± 0.26 mg GAE/g DW) and TFC (1.073 ± 0.18 mg QE/g DW), as well as strong FRSA (82.39%). These green synthesized NPs were evaluated for their anti-diabetic, anti-glycation, and biocompatibility activities. Furthermore, their anti-cancerous activity against HepG2 cell lines was assessed in terms of cell viability, production of reactive oxygen/nitrogen species, mitochondrial membrane potential, and apoptotic caspase-3/7 expression and activity. Synthesized NPs were characterized by techniques including ultraviolet-visible spectroscopy, SEM, EDX, FTIR, and XRD. UV-C mediated monometallic and bimetallic NPs showed well-defined characteristic shapes with a more disperse particle distribution, definite crystalline structures, and reduced sizes as compared to their respective controls. In the case of clinical activities, the highest anti-diabetic activity (67.77 ± 3.29% against α-amylase and 35.83 ± 2.40% against α-glucosidase) and anti-glycation activity (37.68 ± 3.34% against pentosidine-like AGEs and 67.87 ± 2.99% against vesperlysine-like AGEs) was shown by UV-C mediated AgNPs. The highest biocompatibility (IC50 = 14.23 ± 1.68 µg/mL against brine shrimp and 2.48 ± 0.32% hemolysis of human red blood cells) was shown by UV-C mediated ZnONPs. In the case of anti-cancerous activities, the lowest viability (23.45 ± 1.40%) with enhanced ROS/NOS production led to a significant disruption of mitochondrial membrane potential and greater caspase-3/7 gene expression and activity by UV-C mediated bimetallic Ag–ZnONPs (0.1/0.5). The present work highlights the positive effects of UV-C light on physico-chemical physiognomies as well as the clinical activities of NPs.
The Genetics of Diabetes: What We Can Learn from Drosophila
Authors: Liguori Francesco , Mascolo Elisa , Vernì Fiammetta
Published: October 2021

Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to impaired insulin secretion and/or action. All diabetes types have a strong genetic component. The most frequent forms, type 1 diabetes (T1D), type 2 diabetes (T2D) and gestational diabetes mellitus (GDM), are multifactorial syndromes associated with several genes’ effects together with environmental factors. Conversely, rare forms, neonatal diabetes mellitus (NDM) and maturity onset diabetes of the young (MODY), are caused by mutations in single genes. Large scale genome screenings led to the identification of hundreds of putative causative genes for multigenic diabetes, but all the loci identified so far explain only a small proportion of heritability. Nevertheless, several recent studies allowed not only the identification of some genes as causative, but also as putative targets of new drugs. Although monogenic forms of diabetes are the most suited to perform a precision approach and allow an accurate diagnosis, at least 80% of all monogenic cases remain still undiagnosed. The knowledge acquired so far addresses the future work towards a study more focused on the identification of diabetes causal variants; this aim will be reached only by combining expertise from different areas. In this perspective, model organism research is crucial. This review traces an overview of the genetics of diabetes and mainly focuses on Drosophila as a model system, describing how flies can contribute to diabetes knowledge advancement.
Design, Synthesis, Antibacterial, Antifungal and Anticancer Evaluations of Novel β-Pinene Quaternary Ammonium Salts
Authors: Zhang Li , Feng Xue-Zhen , Xiao Zhuan-Quan , Fan Guo-Rong , Chen Shang-Xing , Liao Sheng-Liang , Luo Hai , Wang Zong-De
Published: October 2021

β-pinene is a monoterpene isolated from turpentine oil and numerous other plants’ essential oils, which has a broad spectrum of biological activities. In the current work, six novel β-pinene quaternary ammonium (β-PQA) salts were synthesized and evaluated in vitro for their antifungal, antibacterial and anticancer activities. The in vitro assay results revealed that compounds 4a and 4b presented remarkable antimicrobial activity against the tested fungi and bacteria. In particular, compound 4a showed excellent activities against F. oxysporum f.sp. niveum, P. nicotianae var.nicotianae, R. solani, D. pinea and Fusicoccumaesculi, with EC50 values of 4.50, 10.92, 9.45, 10.82 and 6.34 μg/mL, respectively. Moreover, compound 4a showed the best antibacterial action against E. coli, P. aeruginosa, S. aureus and B. subtilis, with MIC at 2.5, 0.625, 1.25 and 1.25 μg/mL, respectively. The anticancer activity results demonstrated that compounds 4a, 4b, 4c and 4f exhibited remarkable activity against HCT-116 and MCF-7 cell lines, with IC50 values ranged from 1.10 to 25.54 μM. Notably, the compound 4c displayed the strongest cytotoxicity against HCT-116 and MCF-7 cell lines, with the IC50 values of 1.10 and 2.46 μM, respectively. Furthermore, preliminary antimicrobial mechanistic studies revealed that compound 4a might cause mycelium abnormalities of microbial, cell membrane permeability changes and inhibition of the activity of ATP. Altogether, these findings open interesting perspectives to the application of β-PQA salts as a novel leading structure for the development of effective antimicrobial and anticancer agents.
Effects of Variation in Al Content on the Emission of Eu Doped CaAlSiN3 Red Phosphor Synthesized by Combustion Synthesis Method for White LEDs
Authors: Huang Shu-Chi , Chung Shyan-Lung
Published: October 2021

Effects of Al content on the formation and the photoluminescence properties of CaAlSiN3:Eu2+ phosphor (CASIN) were investigated by a combustion synthesis method. XRD (X-ray diffraction), combined with PL (photoluminescence), TEM-EDS (transmission electron microscope equipped with an energy-dispersive X-ray spectroscope), and SAED (selected area electron diffraction) measurements, show that the bar-like CASIN gives a stronger emission than the plate-like and agglomerated fine particles. The emission intensity increases as the Al content increased from Al = 0.2 to Al = 0.8, which resulted from the extent of formation of CASIN increases. Then, the emission intensity decreases as the Al content is increased from Al = 0.8 to Al = 1.5, which resulted from the transformation of morphology of CASIN and a large amount formation of AlN. In addition, the extent of formation of CASIN increases with increasing Al from Al = 0.2 to Al = 1.2 and begins to decrease as Al is further increased to 1.5, and thus the peak emission wavelength increases from 647 nm to 658 nm as the Al molar ratio is increased from 0.2 to 1.2 and begins to decrease when further increasing the Al molar ratio to 1.5, which resulted from the large amount of AlN formed.
Anticancer Activity of Natural and Synthetic Chalcones
Authors: Constantinescu Teodora , Lungu Claudiu N.
Published: October 2021

Cancer is a condition caused by many mechanisms (genetic, immune, oxidation, and inflammatory). Anticancer therapy aims to destroy or stop the growth of cancer cells. Resistance to treatment is theleading cause of the inefficiency of current standard therapies. Targeted therapies are the most effective due to the low number of side effects and low resistance. Among the small molecule natural compounds, flavonoids are of particular interest for theidentification of new anticancer agents. Chalcones are precursors to all flavonoids and have many biological activities. The anticancer activity of chalcones is due to the ability of these compounds to act on many targets. Natural chalcones, such as licochalcones, xanthohumol (XN), panduretin (PA), and loncocarpine, have been extensively studied and modulated. Modification of the basic structure of chalcones in order to obtain compounds with superior cytotoxic properties has been performed by modulating the aromatic residues, replacing aromatic residues with heterocycles, and obtaining hybrid molecules. A huge number of chalcone derivatives with residues such as diaryl ether, sulfonamide, and amine have been obtained, their presence being favorable for anticancer activity. Modification of the amino group in the structure of aminochalconesis always favorable for antitumor activity. This is why hybrid molecules of chalcones with different nitrogen hetercycles in the molecule have been obtained. From these, azoles (imidazole, oxazoles, tetrazoles, thiazoles, 1,2,3-triazoles, and 1,2,4-triazoles) are of particular importance for the identification of new anticancer agents.
Transcriptomic and Metabolic Analyses Reveal the Mechanism of Ethylene Production in Stony Hard Peach Fruit during Cold Storage
Authors: Wang Yan , Deng Li , Meng Junren , Niu Liang , Pan Lei , Lu Zhenhua , Cui Guochao , Wang Zhiqiang , Zeng Wenfang
Published: October 2021

Stony hard (SH) peach (Prunus persica L. Batsch) fruit does not release ethylene and has very firm and crisp flesh at ripening, both on- and off-tree. Long-term cold storage can induce ethylene production and a serious risk of chilling injury in SH peach fruit; however, the regulatory mechanism underlying ethylene production in stony hard peach is relatively unclear. In this study, we analyzed the phytohormone levels, fruit firmness, transcriptome, and lipidome changes in SH peach ‘Zhongtao 9’ (CP9) during cold storage (4 °C). The expression level of the ethylene biosynthesis gene PpACS1 and the content of ethylene in SH peach fruit were found to be upregulated during cold storage. A peak in ABA release was observed before the release of ethylene and the genes involved in ABA biosynthesis and degradation, such as zeaxanthin epoxidase (ZEP) and 8’-hydroxylase (CYP707A) genes, were specifically induced in response to low temperatures. Fruit firmness decreased fairly slowly during the first 20 d of refrigeration, followed by a sharp decline. Furthermore, the expression level of genes encoding cell wall metabolic enzymes, such as polygalacturonase, pectin methylesterase, expansin, galactosidase, and β-galactosidase, were upregulated only upon refrigeration, as correlated with the decrease in fruit firmness. Lipids belonging to 23 sub-classes underwent differential rearrangement during cold storage, especially ceramide (Cer), monoglycosylceramide (CerG1), phosphatidic acid (PA), and diacyglyceride (DG), which may eventually lead to ethylene production. Exogenous PC treatment provoked a higher rate of ethylene production. We suspected that the abnormal metabolism of ABA and cell membrane lipids promotes the production of ethylene under low temperature conditions, causing the fruit to soften. In addition, ERF transcription factors also play an important role in regulating lipid, hormone, and cell wall metabolism during long-term cold storage. Overall, the results of this study give us a deeper understanding of the molecular mechanism of ethylene biosynthesis during the postharvest storage of SH peach fruit under low-temperature conditions.
Ensuring energy efficiency of refrigeration piping
Authors: Petrov G.I. , Kornienko V.N. , Donetskikh A.G.
Published: October 2021

Improving energy efficiency and energy saving in refrigeration technology depends largely on the use of modern thermal insulation materials in the thermal insulation structures of refrigeration pipelines. The article presents a comparative analysis of the thermal characteristics and operational properties of heat-insulating materials used in refrigeration. The features of RUFLEX thermal insulation materials based on foamed synthetic rubber produced from domestic raw materials and their compliance with the requirements of energy efficiency, durability, operational reliability and safety are considered.
Ponthegesztő berendezés gyártása háztartási elektronikai hulladékból
Authors: Bíró Tamás , Renkó József Bálint
Published: October 2021

Napjainkban a ponthegesztési eljárás igen széles körű alkalmazásnak örvend. Ponthegesztett kötésekkel lehet találkozni a hétköznapi élet számos területén: a kenyérpirítón, a számítógép vagy a telefon akkumulátorán, de akár autóipari karosszériaelemeken is. Tekintettel az eljárás elterjedtségére, jogosan merülhet fel az igény a hobbi barkácsműhelyben egy olyan ponthegesztő berendezés iránt, amely kis teljesítményű, de az egyszerű ponthegesztési műveletek elvégzésére alkalmas. Ilyen berendezések léteznek a piacon, ugyanakkor jelen cikk rávilágít arra, hogy költséghatékonyan, akár háztartási elektronikai hulladékok felhasználásával is előállítható a hobbicélokra jól használható ponthegesztő berendezés, lehetőséget teremtve ezzel bizonyos típusú háztartási elektronikai hulladékok újrahasznosítására, erősítve a fenntarthatóság érvényesülését is a mérnöki szemléletben.
Műanyag-vákuumformázó gép tervezése és kivitelezése
Authors: Birton Botond-Antal , Gergely Attila
Published: October 2021

A dolgozat célja egy vákuumformázó berendezés tervezése és kivitelezése, melyet hőre lágyuló polimer lapok formázására lehet használni. A tervezett berendezés A4-es formátumú műanyag lap megmunkálására alkalmas. A berendezés tervezésekor fontos szempont volt a költséghatékony kivitelezés. A berendezés egy államvizsga-dolgozat keretében a Sapientia EMTE Marosvásárhelyi Karának Gépészmérnöki Tanszékéhez tartozó Polimertechnológia laboratórium számára készül oktatási célra. A tervezett berendezés felépítése és működése hasonló az iparban használt gépekéhez, az előállítási költsége viszont jelentősen kisebb. A berendezés főbb alkotóelemei közé tartoznak a következők: vázszerkezet, melegítő, vákuumszivattyú, a formázandó műanyaglap befogó szerkezete.
HUBUNGAN GAYA HIDUP DENGAN KUALITAS HIDUP PADA PENDERITA MASALAH KAKI DIABETIK
Authors: Ritonga Sukhri Herianto , Julianda Dinda Permata , Antoni Adi
Published: October 2021

An increasing number of people with diabetes globally results in an increasing number of complications from diabetes, such as diabetic foot problems. Diabetic foot problem is one of the complications that most causes a decrease in the quality of life in sufferers. The aim of this study was to determine the relationship between lifestyle with quality of life in people with type 2 diabetes with diabetic foot problems. This research uses quantitative research with a case-control design with a retrospective approach. The number of respondents in this study was 50 people using the purposive sampling technique. The measuring instrument used to assess lifestyle is the Fantastic Lifestyle Score, while to assess the quality of life (WHOQOL) BREF. The statistical test used is the chi-square test. In this study, the p-value was 0.044 (α= 0.05) so that statistically there was a relationship between lifestyle with quality of life. Based on the odds ratio, the value was 3.886 (95% CI, 1.191-12.681), meaning that respondents who had a bad lifestyle were 3.8 times more likely to have a bad quality of life. The results showed that lifestyle was significantly related to the quality of life, where the better the lifestyle, the better the quality of life. This research can also be an input for health workers to make health services an effort to increase knowledge about the lifestyle and quality of life of people with diabetes.
«Податкова амністія» у правовій державі: зарубіжний досвід, вітчизняні перспективи
Authors: Каменський Д.
Published: October 2021

У науковій статті здійснено авторську спробу критично проаналізувати новели, передбачені Законом України «Про внесення змін до Податкового кодексу України щодо стимулювання детінізації доходів та підвищення податкової культури громадян шляхом запровадження добровільного декларування фізичними особами належних їм активів та сплати одноразового збору до бюджету». На підставі активного звернення до попередньої законотворчої роботи та опрацювання відповідного зарубіжного досвіду, спрогнозовані деякі перспективи реалізації в Україні так званої податкової амністії.
Кримінологічна характеристика осіб, які вчинили погрозу або насильство щодо працівника правоохоронного органу
Authors: Беленок В.
Published: October 2021

У статті на підставі аналізу судової практики, статистичних даних, результатів досліджень учених розкрито особливості кримінальних правопорушників цієї категорії за ознаками громадянства, національності, віку, статі, освітнього рівня, судимості, співучасті, фізичного стану, працевлаштування та місця проживання. Розроблено кримінологічний портрет особи, яка вчиняє погрози або насильство щодо працівників правоохоронних органів у зв'язку з виконанням цим працівником службових обов'язків: чоловік у віці 25–50 років, громадянин України, місцевий мешканець міста, з загальною середньою або професійно-технічною освітою, котрий офіційно не працевлаштований, зловживає алкогольними напоями та раніше вчинив адміністративне чи кримінальне правопорушення (у певних випадках раніше судимий).
Про необхідність використання Україною позитивного досвіду США з питань розбудови системи інформаційної безпеки
Authors: Пирожик О.
Published: October 2021

У статті розглянуті питання, пов’язані з необхідністю створення в Україні ефективної національної системи забезпечення інформаційної безпеки держави за зразком такої країни, НАТО, як США. Зокрема, проаналізовано нормативно-правові акти США у цій сфері суспільних відносин та позитивний досвід з означених питань, а також запропоновані науково обґрунтовані заходи щодо вирішення означеної проблематики.
Кримінальна відповідальність за недостовірні ствердження: зарубіжний досвід
Authors: Гломб Ю.
Published: October 2021

У статті представлено порівняння окремих розділів кримінальних кодексів різних країн щодо відповідальності за недостовірні ствердження. В світовій юрисдикції лжесвідчення вважається серйозним злочином, який призводить до судових помилок оскільки воно може бути використано для узурпації влади суду. Закони штатів та Європи також карають лжесвідчення. Як правило, вибір міри покарання входить до компетенції суддів і може варіюватися від штрафу і виправних робіт до тюремного ув'язнення.
Роль судового конституційного контролю: основні підходи до розуміння
Authors: Копча В.
Published: October 2021

Стаття присвячена дослідженню сутності та ролі судового конституційного контролю в сучасній державі. Особливу увагу звернуто на роль органів конституційної юрисдикції для гарантування верховенства права і прав людини. Зроблено висновок про те, що для здійснення конституційної юрисдикцію важливим є обмін ідей між національними конституційними судами з приводу розуміння конституції та прав людини.
Lo nacional en crisis: formación en dramaturgia a finales de los años ’60
Authors: Saba Mariano
Published: October 2021

A fines de los ’60 la percepción contextual de una crisis en la existencia del autor nacional parece haber sido condición de posibilidad para la aparición de seminarios y talleres de dramaturgia, los cuales justamente terminarían dando formación iniciática a los escritores del género cuya presencia sería central en los años posteriores. En este sentido, conviene analizar no sólo la paradoja por la cual la polémica dio estímulo a la enseñanza, sino también los hitos más relevantes que surgieron entonces como nodos de formación en la escritura teatral.
Mujeres dramaturgas en Buenos Aires: Mariana “Cumbi” Bustinza, su formación y producción en la escena porteña
Authors: Meza Sofía Elena
Published: October 2021

En el teatro de Buenos Aires el rol de la mujer en la producción dramatúrgica fue muchas veces invisibilizado por las instituciones. A partir de diferentes investigaciones, en la actualidad podemos dar cuenta de su importancia en el desarrollo del teatro, considerando el aporte diverso de actrices, productoras, técnicas y escritoras. Este artículo se focaliza en Mariana “Cumbi” Bustinza, dramaturga en ejercicio actualmente. Para ello se reflexiona sobre su formación, dando cuenta de sus vínculos con la cumbia y la danza. De ese modo el trabajo intenta evidenciar algunas razones de su reconocimiento a nivel nacional.
Proyecto intervención lumínica, de Ricardo Sica. Poniendo el foco en el vacío
Authors: Mauro Karina
Published: October 2021

La pandemia COVID19 ocasionó el cierre de las salas y la total parálisis de la actividad teatral. Los artistas implementaron entonces diversas estrategias, como continuar realizando funciones vía streaming. Ricardo Sica, en cambio, se trasladó a las salas, abrió los espacios e iluminó el vacío. Así nació el Proyecto Intervención Lumínica, que analizaremos en el presente artículo.
The Tianwen-1 Guidance, Navigation, and Control for Mars Entry, Descent, and Landing
Authors: Huang Xiangyu , Li Maodeng , Wang Xiaolei , Hu Jinchang , Zhao Yu , Guo Minwen , Xu Chao , Liu Wangwang , Wang Yunpeng , Hao Ce , Xu Lijia
Published: October 2021

Tianwen-1, the first mission of China’s planetary exploration program, accomplished its goals of orbiting, landing, and roving on the Mars. The entry, descent, and landing (EDL) phase directly determines the success of the entire mission, of which the guidance, navigation, and control (GNC) system is crucial. This paper outlines the Tianwen-1 EDL GNC system design by introducing the GNC requirements followed by presenting the GNC system architecture and algorithms to meet such requirements. The actual flight results for the whole EDL phase are also provided in this paper.
ANALYTICAL PLATFORM OF CUSTOMS ADMINISTRATION: STATE AND PROSPECTS OF DEVELOPMENT
Authors: Makrusev Viktor , Lyubkina Ekaterina
Published: October 2021

The article is the result of a study of customs administration in the context of analytical support. The authors analyzed the existing analytical platform of customs administration. The organizational procedure for analyzing foreign trade activities is described on the example of regional customs administrations. The main characteristics of methods and means of analyzing foreign trade activity are presented and disclosed. In the course of the analysis, the problematic characteristics of the existing analytical platform are identified and promising directions of development are formulated in the conditions of digital transformation and the introduction of intelligent technologies into the practice of analytical activities of customs authorities. Based on the established development conditions, the structure of an intelligent digital platform for analytical support of customs administration has been developed. The authors propose a holistic approach to transforming an analytical platform into a cognitive one and formulate recommendations for implementing the approach in practice.
¿Qué hace un geógrafo hoy? Análisis crítico y reflexiones para un debate impostergable (caso argentino)
Authors: Cuadra Dante Edin
Published: October 2021

El objetivo de este artículo es reflexionar sobre el papel que cumplen los geógrafos en la actualidad, en un contexto caracterizado por grandes, variados y permanentes cambios en el espacio geográfico, los cuales invitan a repensar y redirigir, tanto la disciplina como el quehacer de sus cultores. La metodología empleada consistió en organizar el trabajo analítico en cuatro ejes orientadores: la necesaria autocrítica de los geógrafos sobre su desempeño en la sociedad, la comprensión cabal del contexto en el que se mueven, la toma de conciencia acerca del potencial de la disciplina y de los geógrafos y, por último, el desafío de involucramiento en sus comunidades y territorios. Los resultados ponen en evidencia algunas concepciones, prácticas y omisiones que caracterizaron tradicionalmente, tanto a la disciplina como a sus realizadores, que indujeron a la sociedad a incorporar ideas erróneas sobre qué es la geografía y qué hacen los geógrafos. Consiguientemente, se plantea la necesidad de superar ciertos aspectos acuñados en el ejercicio de la docencia, la investigación y la aplicación. Entre las conclusiones, se destacan: la urgencia de revisar los planes de estudios de las carreras de geografía, priorizar el desarrollo de investigaciones vinculadas a las problemáticas actuales (no siempre visibles), jerarquizar la geografía como profesión y, asimismo, cubrir el gran vacío existente en el ámbito de la geografía aplicada. Ello conduciría al logro de una geografía científicamente más significativa y socialmente más comprometida.
Impressões sobre o Congresso de Milão
Authors: Rodrigues José Raimundo , Vieira-Machado Lucyenne Matos da Costa , Nascimento Gabriel Silva Xavier
Published: October 2021

Trata-se de tradução de texto inédito no Brasil publicado originalmente em 1881. James Denison, autor do texto, foi um dos quatro surdos presentes no Congresso para melhoria da condição dos surdos-mudos, realizado em Milão, de 06 a 11 de setembro de 1880. Na história da educação de surdos o evento italiano goza de muita popularidade, mas pouco aprofundamento e, repetidamente, é apresentado como evento em que se deu a extinção da língua de sinais. O texto de James Denison permite-nos uma visão ímpar sobre o evento, ultrapassando os limites das narrativas tradicionais que projetam sobre Milão apenas a oposição língua de sinais versus oralização. A tradução deste texto para o público brasileiro possibilita problematizar muitas verdades acerca de Milão.
O romance em segunda pessoa: análise estrutural
Authors: Botoso Altamir
Published: October 2021

O artigo traduzido trata do emprego da segunda pessoa em romances hispânicos e também se ocupa de obras da literatura inglesa e francesa. É um dos raros textos teóricos a respeito desse assunto e sua tradução poderá vir a auxiliar futuros estudiosos brasileiros a respeito desta questão tão pouco explorada no âmbito da crítica literária.
De Aristóteles à contemporaneidade:uma arquitetônica da beleza
Authors: Daróz Elaine
Published: October 2021

A temática da beleza, e em especial da beleza feminina, tem sido significada sob diferentes vertentes históricas e teóricas. Pari passu aos procedimentos de estética, cirúrgicos ou não, crescem também os debates acadêmicos sobre esse significante. Neste trabalho, propomos uma reflexão acerca do papel da memória bem como suas implicações no imagino do feminino da atualidade. A partir dos pressupostos teórico-analíticos da Análise do discurso de linha francesa (Pêcheux), tomamos uma histórico-discursiva para pensar os movimentos de deslizamentos / deslocamentos de “beleza” ao longo dos tempos, a fim de uma desnaturalização dos sentidos sobre esse significante, tendo em vista a historicidade a ele inerente.Trazemos, para tanto, o conceito de Arquitetônica, de Aristóteles, e desenvolvemos alguns gestos de interpretação acerca dos efeitos de sentidos sobre o feminino em expressões artísticas ao a partir de um recorte temporal que abarca a Antiguidade clássica, Renascimento e, então, século XX e, ainda, o ressoar desses sentidos na atualidade. Ao longo de nossas reflexões, consideramos o corpo enquanto lugar de memória que direciona sentidos e convocam os sujeitos contemporâneos a ocuparem os seus lugares pré-determinados ideologicamente na esfera social.
A promessa da UFCA
Authors: Nascimento Ives Romero Tavares do
Published: October 2021

A promessa da UFCA.
Joseph von Eichendorff. Poemas em tradução
Authors: Mathias Dionei
Published: October 2021

Joseph von Eichendorff nasceu em 1788 e faleceu em 1857. Na historiografia da literatura de expressão alemã, Eichendorff se encontra entre as mais importantes vozes do Romantismo, ao lado de escritores como Novalis, Ludwig Tieck, Clemens Brentano, Adelbert von Chamisso ou Wilhelm Müller. A presente tradução apresenta vinte poemas de Eichendorff, todos eles canônicos e com uma recepção intensa no espaço cultural de língua alemã. A tradução não recria a estruturação formal dos poemas, optando por uma versão literal dos textos. Sem a riqueza das rimas e sem a estruturação rítmica, a tradução perde uma dimensão central da estética de Eichendorff, mas a despeito dessa perda talvez possa contribuir para um primeiro acesso a seus poemas e para a intensificação de sua recepção. Muitos de seus poemas falam de solidão, fragmentação ou falta de pertencimento, mas também de afirmação existencial no contato com a beleza da natureza e do mundo.
Poesia cantada: encontros e entrelaçamentos, do livro ao videoclipe e vice-versa
Authors: Costa Andreia Aparecida Suli da , Carvalho Kelly Cristiane Henschel Pobbe de
Published: October 2021

O mundo contemporâneo nos acena diariamente com estímulos verbais, visuais e sonoros por todos os lados. Com as crianças não é diferente: no papel ou nas telas, elas convivem com vídeos, canções e livros que permeiam o seu universo fabulado. Da poesia que foi musicada ao livro gestado a partir da canção, são muitos os exemplos desses encontros e entrelaçamentos entre diferentes semioses e suportes na literatura infantil brasileira contemporânea que, inclusive, compõem acervos dos programas do livro que repertoriam nossas escolas públicas. Assim, neste trabalho, apresentamos uma breve análise das obras Assim Assado, de Eva Furnari, e Eu, de Paulo Tatit e Sandra Peres, pertencentes aos acervos do Programa Nacional do Livro Didático – Obras complementares, de 2010, e ao Programa Nacional do Livro Didático – PNLD Literário, de 2018, respectivamente, cotejando-as com os videoclipes das canções que as precederam ou das quais sucedem. Neste percurso, convidamos à reflexão sobre como esses encontros e entrelaçamentos podem ser profícuos para formação do leitor crítico e estético (ECO, 2003), especialmente durante a aprendizagem inicial da língua escrita, no processo de alfabetização e letramento (SOARES, 2016; 2020; MORAIS, 2012; 2019).
Poesia, Humano, Palavra
Authors: Laffin Marcos
Published: October 2021

O resumo é sempre um fragmento. Como um pedacinho dos olhos de cá, parece sempre duvidar dos cílios dos olhos de lá. Será que entendeu? Será que seduziu? Este texto é um texto e na forma de ensaio literário traz a poesia como atividade do humano. A palavra na poesia movimenta um sentido de não-lugar. Neste ensaio se fala da palavra cercada pelo imaginário discursivo e pescada para emergir movimentos. Neste ensaio, em sua condição de provisoriedade, pela transição mutante da polissemia, articula linguagem poética e racionalidade em que procura evidenciar o rigor sem desejar a exatidão, mas não se descuida de aproximar seus enleios, pois em sua finalidade concorrem certas afirmações na busca de sua contrapalavra. O ponto que se exibe como final enseja suas reticências pois a vida ao irromper todos os dias pergunta: quem há de domesticar o mar? Em resposta, a poesia recita, que livre é o humano que compreendeu Ítaca[1].[1] Ítaca é um poema de Kostantinos Kaváfis. Neste ensaio, Ítaca assume o caminho em direção do trabalho de domar o mar. Domar o mar é um trabalho. É um trabalho impossível, mas não menos prazeroso. É assim que para ir a Ítaca, se busca expressar, como no poema, o que vem a ser a felicidade. Felicidade é primeiro uma sensação. Depois reúne um significado, e depois do significar Ítaca é uma palavra que abre infinitamente novos caminhos, novas palavras que retornam sempre à sua origem: domar o mar.
Editorial
Authors: Pinheiro-Mariz Josilene , Costa Marco Antonio Margarido , Oliveira Maria Angélica de
Published: October 2021

Editorial
Apresentação
Authors: Ferreira Eliane Aparecida Galvão Ribeiro , Silva Rosana Rodrigues da , Silva Sara Raquel Duarte Reis da , Pinheiro-Mariz Josilene
Published: October 2021

Apresentação
COMMUNICATIVE GAMES IN LEARNING STUDENTS IN THE CLASSES OF THE KYRGYZ LANGUAGE
Authors: Azemova A.A. , Zhamanakova M.B.
Published: October 2021

The article discusses the training of new generation specialists, the formation of their universal competence. When determining the methodology of teaching the Kyrgyz language, it is proposed to use communicative games.
FEATURES OF THE USE OF MORPHOLOGIC MEANS IN THE TRANSLATION OF CHINESE FAIRY TALES, THE TRAGEDY OF RICHARD III INTO THE KYRGYZ LANGUAGE
Authors: Mambetalieva S. Ch. , Shabdanaliev N. A.
Published: October 2021

Despite the fact that morphemes have been fully investigated and reasoned at a theoretical level, there is currently no comparative study of the morpheme order of translations from Chinese and English into Kyrgyz. The presence of such a study can serve as the best understanding of the structure of a non-native language, which means, contribute to the formation of lexical and grammatical competence. Therefore, we consider and compare the units of the Kyrgyz, Chinese and English words.
The method of theoretical study reveals the main differences, similarities and connections in the systematization of morphemes. The article also explains the main principles of morphemic parsing in these languages.
The analysis indicators may be of interest to Sinologists when developing exercises for solving a linguistic problem - dividing a word into its components.
NEW TENDENCIES OF MODERN ORGANIZATION OF BUSINESS PARKS
Authors: Zhumasheva Z.B. , Halmurzaeva G.B.
Published: October 2021

The paper deals with the formation of an ecologically comfortable environment for administrative purposes, business parks located in the central part of megalopolises on the example of a number of implemented foreign projects. The research focuses on the main trends and designing of modern landscape design in a world practice.
Transformadores de Potencia con Doble Núcleo: Análisis de respuesta a la frecuencia
Authors: Perez Rojas Carlos , Garcí­a Martínez Sigridt
Published: October 2021

El Análisis de Respuesta a la Frecuencia (FRA, Frequency Response Analysis), es una excelente herramienta en el diagnóstico y detección de fallas internas en el transformador como lo son: el desplazamiento y deformación de devanados, debidos a fuerzas electromagnéticas como resultado de corrientes de falla, aflojamiento de los soportes de los devanados a consecuencia de descargas eléctricas o transporte del transformador. Este tipo de fallas están involucradas básicamente con el cambio en la geometría del transformador en su conjunto, factor que altera los parámetros RLC que representan al transformador y por ende sus puntos de resonancia. En la literatura se tiene el estandar del comportamiento de los transformadores trifásicos con núcleo de tres piernas, en este trabajo se realiza el análisis de las pruebas que se obtienen en un transformador de doble núcleo de los que se utilizan en los hornos de arco, cuya característica principal es que alimentan altas corrientes sobre un amplio rango de voltajes.
Tectónica y sismicidad en la Región Volcánica Paricutín - Tancítaro, Michoacán, México
Authors: Gómez Calderón Daniel Alberto , Soria Caballero Diana Cinthia , Corona Chávez Pedro
Published: October 2021

Las regiones tectonomagmáticas activas se caracterizan por presentar sistemas de fallamiento regionales, actividad sísmica y vulcanismo recurrente. La Región Volcánica Parícutin - Tancítaro es una zona estructuralmente compleja y con alta densidad volcánica, que se localiza en el Campo Volcánico Michoacán Guanajuato dentro del sector central del Cinturón Volcánico Transmexicano. En este trabajo se presenta una revisión morfotectónica y sísmica de la Región Volcánica Parícutin - Tancítaro. En esta región coexisten dos sistemas de fallamiento regionales: 1) el Sistema de Fallas Cotija-Nueva Italia, el cual agrupa estructuras con orientación NO-SE y actúa como límite entre el dominio de la Meseta P'urhépecha hacia el norte y los dominios del Graben de Peribán - Los Reyes y la Depresión del Bajo Balsas hacia el sur. 2) El Sistema de Fallas Tepalcatepec-Tangancícuaro, el cual agrupa estructuras con orientación NE-SO, incluyendo abundantes lineamientos volcánicos en la misma dirección y aparentemente condiciona el desarrollo del Graben de Peribán - Los Reyes.
La Región Volcánica Parícutin – Tancítaro presenta una intensa actividad sísmica y se ha caracterizado por haber registrado al menos 7 enjambres sísmicos en los últimos 80 años. Independientemente de la precisión de su ubicación y relativa profundidad de ocurrencia, los enjambres sísmicos se traslapan con los dos sistemas de fallamiento descritos, así como con la presencia de lineamientos volcánicos con edades del Pleistoceno tardío, Holoceno e inclusive recientes (p.ej. los volcanes Parícutin (1943-1952), Pedregal (470-710), Astillero (620-680), Metate (1000-1600)). La concurrencia y recurrencia de los tres elementos tectonomagmáticos sugiere fuertemente que las estructuras tectónicas facilitan el ascenso y emplazamiento de magmas, probablemente asociado con reservorios someros a 4-5 km, 9-10 km y 14-16 km. Dicho escenario conlleva la presencia de peligros geológicos inherentes ligados al vulcanismo y la sismicidad que pueden afectar a las comunidades asentadas en la región. Por lo tanto, se recomienda vigilar la evolución de los procesos tectonomagmáticos en la Región Volcánica Parícutin - Tancítaro por medio de instrumentación geofísica y un análisis permanente de todos los datos.
Aplicación de VolcFlow para simular Avalanchas de Escombros y CDP en los volcanes Popocatépetl, Volcán de Colima y Ceboruco
Authors: Cárdenas Sánchez Enrique , Frí­as Gómez Luis Eduardo , Rangel Flores Elis Olivia , Reyes Mendoza Oscar Dionicio , Valencia Alcaraz Francisco
Published: October 2021

El análisis de los peligros volcánicos permite cuantificar el potencial de riesgo sobre eventos históricos en un contexto social y económico.  Por su ubicación geográfica, México cuenta con al menos 38 centros volcánicos, incluyendo volcanes monogenéticos y estratovolcanes, que han presentado actividad explosiva en los últimos 10 mil años.  Entre los más relevantes se encuentra el volcán Popocatépetl, Volcán de Colima y Ceboruco que mantienen diversas similitudes entre sí, como presentar actividad explosiva reciente y ubicarse sobre una región con una densidad de población y, por tanto, alto grado de vulnerabilidad.  En este contexto, el volcán Ceboruco ha presentado al menos 8 erupciones en los últimos 1000 años, siendo la última la erupción más relevante la de 1870. De igual manera, Volcán de Colima y Popocatépetl han sido dos de los volcanes más activos de México con frecuente emplazamiento y destrucción de domos de lava en los últimos 20 años. La actividad explosiva de ambos volcanes ha provocado la evacuación preventiva en diversas ocasiones por parte de autoridades correspondientes. Para nuestro análisis, hemos utilizado el código VolcFlow, escrito en MATLAB, que resuelve las ecuaciones de conservación de masa y momento para el análisis de dispersión y alcance de los flujos.  El presente artículo muestra los resultados del análisis de la modelación de diversos peligros volcánicos como son lahares, flujos piroclásticos y avalanchas de escombros con enfoque hacia la mitigación de riesgo volcánico. Los resultados nos permiten realizar modificaciones efectivas sobre los parámetros reológicos que son característicos para cada tipo de peligro volcánico en cada volcán considerando las características particulares como es densidad de flujo, la viscosidad, volumen de material emitido y por supuesto, Modelo de Elevación Digital.