bluuebunny/crossref_metadata_2025 huggingface dataset:
Rare Thymoma With Solitary Liver Metastasis
Authors: Abusuliman Mohammed , Aboeldahb Moataz , Olimy Abdullah , Abbas Omar , Abusuliman Amr , Jamali Taher , Gavidia Rosario Agustin , Yuan Lisi , Pompa Robert
Published: November 2024

Thymomas are rare, malignant, epithelial tumors of the thymus gland. Extrathoracic metastasis of thymoma is exceedingly rare, particularly when isolated to the liver. We report an 89-year-old man who presented with urinary retention. Exploratory computed tomography imaging revealed a heterogeneous mass in the aortopulmonary window and a 1.9 cm lesion in the left hepatic lobe. Results from magnetic resonance imaging, positron emission tomography-computed tomography, and histopathological analysis of biopsy samples collectively supported a diagnosis of metastatic type B2 thymoma. To the best of our knowledge, this is the oldest patient to be diagnosed with metastatic type B2 thymoma. Metastatic thymoma is difficult to identify, and patients with mediastinal mass identified after any presentation should be evaluated for malignant spread.
O ensino de ciências por investigação: reflexões de professoras em formação continuada
Authors: De Melo Débora Kélli Freitas , Wenzel Judite Scherer
Published: November 2024

Este artigo contempla uma descrição e análise dos diálogos formativos de um grupo de formação continuada de professoras que atuam nos anos iniciais do Ensino Fundamental. O processo formativo vivenciado teve como pressupostos teóricos os modelos de Investigação-Formação-Ação e Investigação-Formação-Ação no Ensino de Ciências com aportes da perspectiva histórico-cultural. O objetivo consistiu em observar e entender como se mostram as compreensões do Ensino de Ciências por Investigação nas espirais autorreflexivas do processo de Investigação-Formação-Ação vivenciado. Os resultados, que foram elaborados num viés da Investigação-Ação crítica e com aporte analítico da Análise Textual Discursiva, nos mostram a importância do planejamento coletivo, das trocas de experiências, também da especificidade e das fragilidades na compreensão dos conteúdos de Ciências e indiciam o posicionamento de protagonista da professora tanto em sala de aula como nos espaços formativos.
Club de ciencias como estrategia de iniciación y divulgación científica en la educación básica en Brasil
Authors: Pereira Carolina Machado Rocha Busch , Viana Rodney Haulien Oliveira , De Sousa Nilciane Pinto Ribeiro , Carloto Denis Ricardo
Published: November 2024

Considerando los Clubes de Ciencias como una estrategia relevante para la enseñanza de las ciencias, esta investigación tiene como objetivo relatar las actividades de iniciación y divulgación científica, desarrolladas en un Club de Ciencias con estudiantes de Educación Básica como aporte al proceso de enseñanza y aprendizaje en el área de Ciencias Naturales. La investigación se llevó a cabo en una escuela pública de la ciudad de Araguaína, ubicada en el norte del estado brasileño de Tocantins. A través de los relatos de las actividades, se evidenció que la educación científica estuvo presente durante el desarrollo de dicho club, y que la iniciativa favoreció el acercamiento entre los estudiantes y la ciencia; además, proporcionó iniciación y divulgación científica, con el fin de contribuir al protagonismo y autonomía de los alumnos que participaron. Aquí, se asume que los Clubes de Ciencias pueden ampliar las posibilidades de aprendizaje de los alumnos, crean experiencias en diferentes espacios, de alejan de la rigidez del aula y del currículo tradicional, en busca de una acción más enfocada a la práctica de actividades en espacios no formales de educación. Promover espacios de investigación en la educación básica es, entonces, tarea de la universidad pública, y esta aproximación puede contribuir para el cumplimiento de la meta 4 de los Objetivos de Desarrollo Sostenible de la Organización de las Naciones Unidades, que busca, para el 2030, que todas las niñas y niños completen su Primaria y Secundaria, con una educación de calidad, a la edad adecuada, y que se asegure la oferta gratuita en la red pública, situación que arrojará resultados de aprendizaje satisfactorios y relevantes.
Primer estudio de muestras palinológicas aéreas y de sedimentos con aplicación en ciencias forenses, en el sudoeste de la provincia de Buenos Aires, Argentina
Authors: Rodríguez Rendas R. David , Murray María Gabriela , Fagúndez Guillermina A.
Published: November 2024

Este estudio se enfocó en analizar y comparar muestras palinológicas aéreas y de sedimentos de dos sitios en los alrededores de la ciudad de Bahía Blanca con el fin de asociar los espectros polínicos de las muestras con los ambientes de procedencia y su posible utilización en un futuro escenario forense. Se examinaron los granos de polen recolectados en tres matrices: sedimento superficial, sedimento recolectado del calzado y granos de polen retenidos en telas. La información palinológica reveló una gran similitud en la composición entre las diferentes matrices de recolección en cada sitio, y una diferencia significativa entre los distintos sitios de recolección. Los tipos polínicos dominantes variaron según el ambiente de muestreo y se vincularon con la vegetación de influencia en cada uno. Los resultados sugieren que las especies de polinización anemófila predominaron en ambos sitios, la representación polínica reflejó la cercanía de las fuentes emisoras y se relacionó con la composición florística local. Además, se encontraron tipos polínicos alóctonos, lo que indica influencias regionales y extra-regionales en los espectros polínicos. El presente estudio indica que los espectros polínicos son capaces de establecer asociaciones geográficas entre las muestras, diferenciando claramente los sitios de estudio, y a su vez poniendo de manifiesto la utilidad de esta disciplina para vincular objetos o individuos con escenarios forenses.
Opportunities Following the Path to Sustainability at Universidad San Francisco de Quito
Authors: Espinoza Camila , Proano-Alives Juan
Published: November 2024

Since 2013, Universidad San Francisco de Quito (USFQ) has utilized various global and national sustainability assessment tools, including STARS by AASHE, UI Green Metrics, Q.S. Sustainability, and THE Impact Ranking. These tools have been pivotal in diagnosing institutional strengths and weaknesses, identifying opportunities for improvement, and integrating strategic actions into our policies and institutional plans. This paper explores the comparative effectiveness of these diverse sustainability evaluation tools and analyzes their impact on decision-making processes at USFQ. It explores how these assessments have informed our sustainability policies and strategies over the years, leading to significant improvements within our institution. Additionally, the paper presents successful case studies from USFQ where these tools have directly influenced the implementation of various projects. The insights provided will demonstrate how rigorous assessments can pave the way for meaningful institutional enhancements, offering a valuable resource for academic institutions worldwide to foster a culture of sustainability and make informed decisions that drive institutional change towards greater sustainability.
Research and Teaching for Sustainability in the RUDN University
Authors: Filippov Vladimir , Savenkova Elena , Redina Margarita
Published: November 2024

More than 30 years ago, the participation of RUDN in the Earth Summit in Rio became an important moment in the university’s history: it was decided to create the first comprehensive ecological faculty in Russia. Now half of the history of our university is also the history of environmental education in Russia. During this time, more than 10,000 ecologists and hundreds of specialists in other sustainability areas were trained. Almost all programs at the university include aspects of sustainability. Over 15 MOOCs and 10 interdisciplinary courses on relevant aspects have been developed. Annually, over 1,000 specialists improve their skills in various aspects of sustainability. An extensive research program in the areas of environmental safety and sustainability includes only in recent years: a program on environmental safety of transport (a part of the Federal project “Clean Air”); expert work on the implementation of BATs. In 2021, Russia’s first Body for the Validation and Verification of Greenhouse Gases was successfully accredited in the university. More than 100 students are annually involved in the campus environmental monitoring program. Since 2022, the university presents a sustainability report. The environmental policy is presented on the university website and has been successfully implemented since 2017. We are confident: the role of the university is the formation of personality, the promotion of the sustainability ideas on the example of its home university.
Utility Model for Climate Change Adaptation at El Bosque University: Circular Economy Approach to Paper and Cardboard Waste
Authors: Romero-Infante Jaime Alberto , Leal-Cardenas Juan Sebastian , Forero-Calderon Javier
Published: November 2024

The impact of climate change has intensified the urgency of adopting sustainable practices in academic institutions, highlighting the need for innovative models that not only mitigate environmental impact, but also promote effective adaptation. This paper presents a pioneering approach focused on the development of a utility model designed specifically for climate change adaptation in the context of Universidad El Bosque. The paper focuses on the implementation of circular economy strategies, focusing on the efficient management of usable waste generated at the institution, specifically for cardboard and paper. This model, the result of interdisciplinary research, not only proposes tangible solutions to reduce the university's carbon footprint, but also establishes an exemplary paradigm for other educational institutions on their path towards environmental sustainability. In the development of the research and analysis of the data recorded by the Environmental Management Unit, it is determined that the rate of generation of usable waste from the university corresponds to a total of 19,475 kilograms for the 2023 period. Therefore, through the detailed analysis of the implementation and results obtained, this article seeks to contribute to the advancement of knowledge in a useful model for adaptation to climate change, with a practical and replicable approach in university environments and beyond, which consists of proposing a model for the implementation of a process of transformation of cardboard and paper waste, for the production of stationery items that can be sold in the university store, promoting reuse, circular economy and sustainability.
Advancing Sustainability through Energy Innovation and Climate Action: Insights from ETUT
Authors: Mezilov Gurbanmyrat , Toyjanov Mekan , Ekayev Mukam , Annamuradov Dovlet , Babayeva Mavluda , Orazov Yslam
Published: November 2024

This study explores the potential of sustainable energy solutions to address global energy challenges and mitigate climate change. Oguz Han Engineering and Technology University (ETUT) serves as a case study, displaying its innovative approaches to energy efficiency, waste management, and renewable energy production. The university's implementation of energy-saving devices, smart building automation systems, and LED lighting demonstrates a commitment to reducing carbon emissions and promoting sustainable practices. Additionally, the study investigates the conversion of plastic waste into liquid fuel and the production of bioethanol from cotton stalks as potential solutions for waste management and renewable energy generation. Further, the research explores the deposition of thin film bismuth vanadium tetraoxide for hydrogen production, highlighting its potential as a clean energy source. Overall, this study emphasizes the importance of sustainable energy solutions and the role of academic institutions in driving innovation and promoting a greener future.
Impacto de la mutación T315I en el pronóstico de la leucemia mieloide crónica
Authors: Kaleem Bushra , Shahab Sadaf , Shamsi Tahir Sultan
Published: November 2024

Objetivos

Las mutaciones dominio quinasa BCR-ABL1 son una de las principales causas de resistencia a los inhibidores de la tirosina quinasa (ITK) en la leucemia mieloide crónica (LMC), siendo la mutación T315I la más resistente a tratamiento. El objetivo del presente estudio es determinar la frecuencia de T315I y su impacto en el pronóstico de la enfermedad, en términos de progresión de enfermedad y supervivencia.

Métodos

Se clasificó como pacientes sin respuesta a tratamiento a aquellos pacientes con respuesta clasificada como “en advertencia” o que no mostraron respuesta completa a tratamiento con ITK, según los criterios de LeukemiaNet (ELN). La mutación T315I se detectó mediante el sistema de mutación refractario a la amplificación por PCR (ARMS-PCR), cuyo resultado fue posteriormente validado mediante secuenciación. Se realizó un seguimiento de 96 meses para observar el impacto de la mutación en el pronóstico de estos pacientes.

Resultados

De los 102 pacientes que no respondieron a tratamiento, la mutación T315I fue detectada en el 21,6 %, con mayor preponderancia entre las mujeres. El 59 % de los pacientes portadores de la mutación presentaron un riesgo basal bajo por la escala Sokal. El 58,8 % de los portadores desarrollaron progresión de la enfermedad a la fase blástica. La supervivencia general (periodo de estudio: 96 meses) de los portadores de la T315I fue del 81,8 % de los pacientes portadores. Los pacientes que progresaron a la fase blástica presentaron mayor probabilidad de ser portadores de la mutación T315I.

Conclusiones

Una respuesta subóptima o falta de respuesta a tratamiento con ITK indica el desarrollo de resistencia debido a la presencia de la mutación T315I o de otras mutaciones. La identificación temprana de esta u otras mutaciones ayudaría a reorientar el tratamiento del paciente.
Marketing von elektronischen Informationsdienstleistungen
Authors: Georgy Ursula
Published: November 2024

Das Thema Informationsmarketing nahm Ende der 1990er- und Anfang der 2000er-Jahre an Fahrt auf, nachdem sich das Dienstleistungsmarketing als Spezialform des Marketings in vielen Bereichen und Branchen bereits etabliert hatte. Durch ChatGPT und andere KI-Tools hat das Thema noch einmal eine deutliche Wendung erfahren. Der Beitrag gibt einen Überblick über die Entwicklung der letzten 25 Jahre; zudem wird ein Ausblick auf mögliche Entwicklungen gewagt.
Historische Obstsorten neu entdeckt: Citizen Science an der Universitätsbibliothek Kiel
Authors: Christ Andreas , Vetter Angila
Published: November 2024

Das Projekt zum „Obstbuch“ von 1859 der Universitätsbibliothek Kiel verbindet historische Forschung mit einem modernen, digitalen Ansatz der Citizen Science. Durch die Einbeziehung von Bürgerwissenschaftlerinnen und Bürgerwissenschaftlern werden historische Obstsorten botanisch analysiert, um Erkenntnisse für den Sortenerhalt zu gewinnen. Der Beitrag stellt die methodischen Ansätze vor, beleuchtet die Bedeutung für die botanische Forschung und diskutiert Aspekte guter wissenschaftlicher Praxis. Dabei wird das Obstbuch als Ausgangspunkt für die Untersuchung aktueller, gesellschaftsrelevanter Fragestellungen genutzt, die mithilfe moderner digitaler Methoden der Citizen Science erforscht werden.
Increased specificity of the “GFAP/UCH-L1” mTBI rule-out test by age dependent cut-offs
Authors: Ladang Aurélie , Vavoulis George , Trifonidi Ioulia , Calluy Emma , Karagianni Katerina , Mitropoulos Athanasios , Vlachos Konstantinos , Cavalier Etienne , Makris Konstantinos
Published: November 2024

Objectives

Mild traumatic brain injury (mTBI) remains challenging to diagnose effectively in the emergency department. Abbott has developed the “GFAP/UCH-L1” mTBI test, to guide the clinical decision to perform a computed tomography (CT) head scan by ruling out the presence of mTBI. We evaluated the diagnostic accuracy of the “GFAP/UCH-L1” mTBI test in a Greek cohort and established age-dependent cut-offs.

Methods

A total of 362 subjects with suspected mTBI and admitted to the Emergency department of the KAT General Hospital of Athens, Greece were recruited for the study. All subjects underwent a CT head scan to establish the diagnosis of mTBI. GFAP and UCH-L1 were measured using Alinity I (Abbott). 163 healthy subjects served as controls.

Results

Using the manufacturer’s cut-offs (35 ng/L for GFAP and 400 ng/L for UCH-L1), the “GFAP/UCH-L1” mTBI test had a sensitivity of 99.1 % and a specificity of 40.6 %. However, the specificity dropped to 14.9 % in patients older than 65 years old. By defining a new cut-off of 115 ng/L for GFAP and 335 ng/L specifically for patients older than 65 years, specificity was increased up to 30.6 % without changing test sensitivity and the number of CT head scans avoided was doubled in this subgroup.

Conclusions

The “GFAP/UCH-L1” mTBI test is an efficient “rule-out test” to exclude patients suffering from mTBI. By adjusting the cut-offs in patients older than 65 years old, we could significantly increase the number of CT head scans avoided without affecting the sensitivity. These new cut-offs should be externally validated.
Time pressure in diagnosing written clinical cases: an experimental study on time constraints and perceived time pressure
Authors: Hooftman Jacky , Olson Andrew P.J. , McQuade Casey N. , Mamede Sílvia , Wagner Cordula , Zwaan Laura
Published: November 2024

Objectives

Time pressure and time constraints have been shown to affect diagnostic accuracy, but how they interact is not clear. The current study aims to investigate the effects of both perceived time pressure (sufficient vs. insufficient time) and actual time constraints (lenient vs. restricted time limit) with regard to diagnostic accuracy.

Methods

Residents from two university-affiliated training programs in the USA participated in this online within-subjects experiment. They diagnosed cases under two perceived time pressure conditions: one where they were told they had sufficient time to diagnose the cases and one where they were told they had insufficient time. The actual time limit was either restricted or lenient (± one standard deviation from the mean time to diagnose). Participants provided their most likely diagnosis and a differential diagnosis for each case, and rated their confidence in their most likely diagnosis.

Results

A restricted time limit was associated with lower accuracy scores (p=0.044) but no effects of perceived time pressure on diagnostic accuracy were found. However, participants self-reported feeling more time pressure when they thought they had insufficient time (p<0.001). In addition, there was an effect of the actual time limit (p=0.012) and perceived time pressure (p=0.048) on confidence.

Conclusions

This study showed that a restricted time limit can negatively affect diagnostic accuracy. Although participants felt more time pressure and were less confident when they thought they had insufficient time, perceived time pressure did not affect diagnostic accuracy. More research is needed to further investigate the effects of time pressure and time limits on diagnostic accuracy.
Exploring the effect of translating non-verbal elements in film subtitles
Authors: Mouzannar Melissa E. , Abou Fadel Saad Gina E.
Published: November 2024

This study investigates the relevance of including the translation of non-verbal elements in film subtitles. It suggests that non-verbal elements play a crucial role in understanding films and, consequently, need to be considered when translating: what is non-verbal becomes written in the translation, carrying a significant semantic load. The article presents an empirical study adopting a qualitative approach that aims to explore and analyse the effect of including non-verbal translation in film subtitles, particularly in a Lebanese movie titled The Insult, subtitled in French. The results show that non-verbal communication and its semantic value should be explicit in subtitling to the foreign-language audience, whether explicitly apparent, graphically represented, or implicitly present between words and lines.
Posedición y paridad humano-máquina en traducción automática neuronal: Un estudio empírico desde la traducción profesional
Authors: Toledo-Báez Cristina
Published: November 2024

Albeit controversial, human-machine parity in neural machine translation has been claimed, but there is a lack of empirical studies providing concrete evidence. This article aims to present part of the results of an experiment conducted under the NEUROTRAD project where human-machine parity in neural machine translation is approached from the perspective of post-editing effort. Combining descriptive statistics, Friedman test for hypothesis testing, and Spearman correlation coefficients, our study analyses the answers to two questionnaires by 36 Spanish freelance translators in order to test 1) whether the type of translation —human, machine translation, and, as a novelty, post-edited machine translation— impacts on the perceived post-editing effort, time, and quality and 2) whether the participant’s professional experience correlates with the perceived post-editing effort, time, and quality. Results revealed that, on the one hand, the type of translation has no influence on the perceived post-editing effort (p<0.953), time (p<0.439) and quality (p<0.390) and, on the other hand, having more post-editing experience does not correlate with 1) perceived post-editing effort for post-edited machine translation (p<0.094); 2) perceived post-editing time for human translation (p<0.259) and post-edited machine translation (p<0.187) and 3) perceived translation quality for post-edited machine translation (p<0.10).
Fatigue life of friction stir spot welds between Z91 magnesium alloy and ENAW7075-T651 aluminum alloy
Authors: Ekinci Omer , Balalan Zulkuf
Published: November 2024

Magnesium (Mg) and aluminum (Al) alloys are considered to be among the lightest structural metals. Using these materials in a design can considerably decrease weight, which brings many benefits like reducing fuel consumption and increasing the performance of an aircraft or a ground vehicle. However, these alloys are too difficult to be joined via fusion welding techniques. In this context, welding AZ91 Mg alloy to ENAW7075-T651 Al alloy by the solid-state welding method of friction stir spot welding was investigated comprehensively. These alloys were welded by utilizing a tool with a triangle pin and various tool rotational speeds (1,000, 1,400, and 1,800 rpm) and welding times (3 and 6 s). Macro and microstructure of the welds and their hardness, tensile strength, and tension-compression fatigue life were determined. Generally, an improvement in the mechanical properties of the weld was observed by increasing the welding time due to the expansion of the joining area. The welding with the best mechanical properties was obtained at 1,400 rpm, and the worst at 1,800 rpm. All the welds failed from the weld area during the tensile and fatigue tests and exhibited a brittle fracture mode due to the formation of intermetallic compounds in the welds.
Degeneracy mediated thermal emission from nanoscale optical resonators with high-order symmetry
Authors: Wang Zexiao , Li Jiayu , Li Zhuo , Liu Xiu , Zhong Yibai , Huang Tianyi , Shen Sheng
Published: November 2024

Conventional thermal emitters, such as a blackbody or the incandescent filament of a light bulb, lack the directionality or narrow linewidth required in many applications such as thermophotovoltaics and infrared sensing. Although thermal emission from bulk materials is well understood based on phenomenological heat transfer concepts like emissivity and the framework of classical electrodynamics, there still remains a significant gap in our understanding of thermal emission at the nanoscale. In this work, by leveraging the quasi-normal mode theory, we derive a general and self-consistent formalism to describe the thermal radiation from nanoscale resonant thermal emitters with high-order symmetric geometries, which are the basic building blocks of metasurfaces and metamaterials. The complex symmetrical geometries of the emitters yield degeneracy of quasi-normal modes. The introduction of the degeneracy can strongly mediate far-field thermal emission from nanoscale resonators, which is closely correlated to the number of degenerate modes and the coupling among the degenerate modes. Our formalism from the quasi-normal mode theory serves as a general guideline to design the complex metastructures with high-ordered degeneracy to achieve optimized absorption or emission capabilities.
Crystal structure of di-glycylglycinium squarate dihydrate, C12H22N4O12, at 105 K
Authors: Gomes Etelvina de Matos , Baptista Rosa M.F. , Görbitz Carl Henrik
Published: November 2024

C12H22N4O12, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 6.7126(4) Å, b = 7.7536(5) Å, c = 8.5279(5) Å, α = 89.4803(14)°, β = 86.2595(14)°, γ = 79.4035(14)°, V = 435.35(5) Å3, Z = 2, R

gt
(F) = 0.0323, wR

ref
(F
2) = 0.0908, T = 105(2) K.
Acryloyl starch/carboxymethyl cellulose grafting copolymerization composite hydrogel for efficient adsorption of methylene blue
Authors: Liu Xue-Li , Sun Ya-Li , Hu Zhong-Zhu , Zhu Chun-Feng
Published: November 2024

An efficient composite adsorbent was prepared based on acryloyl starch/carboxymethyl cellulose grafting copolymerization for the adsorptive removal of methylene blue. The developed composite hydrogels were characterized by means of FTIR, SEM (EDS-SEM), and XRD. Various parameters affecting the removal of methylene blue such as the type of adsorbents, pHs, the amount of adsorbents dosage, initial methylene blue concentration, and contact time were optimized using a series of batch adsorption experiments. The experimental data of the adsorption process were more fitted to Langmuir isotherm (R
2 = 0.9898) with a maximum adsorption capacity of 483.5 mg/g and batch kinetic experiments revealed that the adsorption process followed quasi-second-order kinetic model. The adsorption process was rapid and equilibrium was reached within 30 min. When the adsorption dosage is 0.2 g L−1, the adsorption yield for 100 mg L−1 methylene blue solution can reach 96.7 %. Therefore, acryloyl starch/carboxymethyl cellulose grafting copolymerization composite hydrogel present excellent adsorption efficiency, shows the potential application in future treatment of dyes wastewater.
Carga de trabalho, cansaço e impotência entre profissionais de enfermagem no enfrentamento da COVID-19
Authors: Lopes Barbosa Marcus Levi , Lessa Horta Rogerio , Guedes Lucini Thaís Caroline , Guimarães Camargo Eduardo , Lutzky Bibiana Andrade , Silveira Aline Faria , Zanini Lizziê , Feltrin Djulia Brombilla , Guimarães Dalton , Marasca Mateus Alan , Tavares Nicolas Conter
Published: November 2024

Objetivo: investigar a relação entre carga de trabalho e o registro de cansaço e impotência em profissionais de enfermagem na linha de frente contra a COVID-19. Método: estudo misto, na etapa transversal com 91 profissionais de um hospital público do Rio Grande do Sul, 31 dos quais foram entrevistados em profundidade. Utilizaram-se o Self-Reporting Questionnaire, Perceived Stress Scale e Oldenburg Burnout Inventory, analisados estatisticamente. Resultados: indicam correlação positiva moderada entre cansaço e impotência (p<0,01), ambos correlacionados positivamente com carga de trabalho (p<0,05) e negativamente com experiência profissional (p<0,05). Regressões lineares indicaram o tempo de exercício profissional como preditor negativo (p<0,05) para cansaço e impotência e o número de horas trabalhadas na semana como preditor positivo do cansaço (p<0,05) e adjuvante no modelo final para impotência (p=0,089), com bom ajuste (p=0,013). Conclusões: é necessário ajustar a proteção das equipes em relação ao volume e à extensão das jornadas de trabalho.
More Than a Small Brain: The Importance of Studying Neural Function during Development
Authors: Dooley James C. , van der Heijden Meike E.
Published: November 2024

The nervous system contains complex circuits comprising thousands of cell types and trillions of connections. Here, we discuss how the field of “developmental systems neuroscience” combines the molecular and genetic perspectives of developmental neuroscience with the (typically adult-focused) functional perspective of systems neuroscience. This combination of approaches is critical to understanding how a handful of cells eventually produce the wide range of behaviors necessary for survival. Functional circuit development typically lags behind neural connectivity, leading to intermediate stages of neural activity that are either not seen in adults or, if present, are considered pathophysiological. Developmental systems neuroscience examines these intermediate stages of neural activity, mapping out the critical phases and inflection points of neural circuit function to understand how neural activity and behavior emerge across development. Beyond understanding typical development, this approach provides invaluable insight into the pathophysiology of neurodevelopmental disorders by identifying when and how functional development diverges between health and disease. We argue that developmental systems neuroscience will identify important periods of neural development, reveal novel therapeutic windows for treatment, and set the stage to answer fundamental questions about the brain in health and disease.
You Get What You Pay For: Human Capital Impact on Organizational Performance in Portugal
Authors: Portovedo Ligia , Veloso Ana , Portela Miguel
Published: November 2024

The neoliberal trend in human resource management has been to increase corporate profits by cutting personnel expenses. Mean while, corporate leaders continue to give official speeches clamming that people are their greatest asset. By applying a longitudinal approach to the organizational scope of the phenomenon, we explored the possible relationship between investment in human capital and organizational performance in Portuguese companies from 2010 to 2016. Our findings indicated that a 1% increment in investment in human capital increased gross value added by 0.63% the same year, and by 0.65% if the increase remained consistent over 2 years. The organizational context in which behaviours occurred, represented by the life cycle stage variable, also positively impacted performance, especially when investment in human capital was made in stage 4- decline. Our findings led us to conclude that cutting personnel expenses is detrimental to company performance and contributes to poorer business results.
Diagnostic reference levels (DRL) in Computed Tomography during the period 2018-2022 in a private hospital in Chile
Authors: Seijas Acosta Jugleys , Sanguesa M Javiera , Soffia S Pablo , Fabri G Daniella
Published: November 2024

The aim of this study was to compare and optimize the diagnostic reference levels (DRL) of our institution obtained over 5 years, in order to find the appropriate balance between the patient dose and the quality of the clinical image for the most frequently used CT examinations.The typical values of 6 CT scanners of an institution were evaluated, taking as a reference the DRLs established in 2018. An optimization process was initiated in order to find the best balance between dose- diagnostic quality, finding that the DRLs obtained during that year were well below those published by the ACR, so we proceeded to prioritize the quality of the image by reasonably increasing the doses to the patient. In 2022, we purchased other patient dose monitoring software and got new optimized DRLs.The results obtained from the typical  values of 2018 versus 2022 had a difference of 25% to 30%, with the DRLs of 2022 being higher as we were looking for, finding a significant improvement in the quality of the diagnostic images. The medians obtained are within what is published internationally, which is an indicator that our DRLs are within international standards.This research helped our CT Service considerably to obtain typical values with excellent quality of diagnostic images, and to standardize the protocols for all our CT scanners despite being of different brands and technology.
Türkiye’de gerçekleştirilen lisansüstü tez çalışmalarında pes planusu belirlemede kullanılan tanı kriterlerinin incelenmesi
Authors: Ören Aslı , Ünver Banu , Bek Nilgün
Published: November 2024

Amaç: Bu çalışma ülkemizde gerçekleştirilen lisansüstü tezlerde pes planusun belirlenmesinde kullanılan tanı kriterlerini incelenmek ve sonuçları güncel literatürle tartışmak amacıyla planlandı.
Yöntem: Yükseköğretim Kurulu Ulusal Tez Merkezi veri tabanında “pes planus, düztaban, kalkaneovalgus, pronasyon, arka ayak eversiyonu/valgusu, düşük ark, pes planovalgus, içe basma, ayak postürü, medial longitudinal ark, naviküler yükseklik, naviküler düşme, ayak izi, pedobarografi” anahtar kelimeleri kullanılarak 147 lisansüstü çalışmaya ulaşıldı. Dahil edilme kriterlerini sağlayan 117 çalışma incelendi.
Bulgular: Pes planusu belirlemek için en sık kullanılan yöntemler Naviküler Düşme Testi (NDT) (n=40; % 34,18), Ayak Postür İndeksi (APİ) (n=37; %31,62) ve ayak izi (n=15; % 12,82) yöntemiydi. NDT kriterinin sıklıkla 10 mm ve üzeri, APİ kriterinin ise çoğunlukla 6 ve üzeri değerlerinin dikkate alındığı görüldü. Ayak izi yönteminde daha çok Staheli Ark İndeksi, Ark İndeksi ve Chippaux-Smirak İndeksi kullanıldığı belirlendi. Tezlerdeki bireylerin en sık değerlendirildiği sonuç ölçütleri denge, pedobarografi, kas kuvveti, ayak fonksiyonu, yaşam kalitesi ile ilgiliydi.
Sonuç: Pes planusun belirlenmesinde kullanılan tanı kriterleri açısından bir fikir birliği bulunmadığı görüldü. Literatürde geçerli ve güvenilir kabul edilen ölçüm yöntemlerin tartışılan avantaj ve dezavantajları ışığında klinik karar vermenin ve ölçüm hatalarının etkisini en aza indirmek için farklı test sonuçlarının birleştirilmesinin doğru bir yaklaşım olabileceği değerlendirildi
Investigation of gait symmetry, cervical joint position sense, cervical range of motion and functional disability in individuals with chronic idiopathic neck pain
Authors: Ayan Hatice , Kara Bilge , Erbayraktar Reşat Serhat
Published: November 2024

Purpose: Gait asymmetry has not been adequately clarified in Chronic Idiopathic Neck Pain (CINP). Cervical position sense is important to maintain gait function. However, the association between gait symmetry and cervical position sense is unknown. The first aim is to evaluate gait symmetry, cervical joint position error (JPE), cervical range of motion (ROM), and functionality in persons with CINP and compare them with healthy controls (HC). The second aim is to investigate the relationship between gait symmetry and cervical JPE, ROM, and functional disability in CINP.
Methods: 35 persons with CINP (27 females, eight males, mean age 25.48 ± 8.69 years) and 34 HC (25 females, nine males, mean age 25.76±7.96 years) were included. Gait symmetry was assessed with a wearable sensor gait device. Cervical JPE and ROM were evaluated with the Cervical Range of Motion (CROM) device. Neck Disability Index (NDI) was used for functional disability.
Results: Persons with CINP had significantly worse gait symmetry, cervical JPE, and lower cervical range of motion in all directions (p
Fizyoterapi ve rehabilitasyon öğrencilerinin Web 2.0 araçlarına yönelik davranışlarının incelenmesi: Hacettepe Üniversitesi örneği
Authors: Ayvat Fatma , Doğan Mert , Ayvat Ender , Onursal Kılınç Özge , Sütçü Gülşah , Kılınç Muhammed , Aksu Yıldırım Sibel
Published: November 2024

Amaç: Teknolojik gelişmelerle birlikte Web 2.0 teknolojilerinin eğitimde kullanılması ve bu yöntemle birlikte eğitimin dinamik bir hale gelmesi, son yıllarda bu alandaki en dikkat çekici konulardan birisidir. Bu çalışmanın amacı, Fizyoterapi ve Rehabilitasyon öğrencilerinin eğitimde Web 2.0 teknolojilerinin kullanımına yönelik davranışlarının ve sıklığının değerlendirilmesidir.
Yöntem: Araştırmacılar, literatürde yer alan Web 2.0 araçlarını tarayarak bir değerlendirme formu oluşturdu. Öğrencilere ‘Google Forms’ üzerinden sunulan değerlendirme formunda, eğitimde online sınıf oluşturmak veya toplantı yapmak, ortak çalışma sağlamak, içerik geliştirmek, veri toplamak, interaktif soru araçları, online eğitim platformları ve sosyal medyaya ulaşmak için kullandıkları araçların hangileri olduğu ile ilgili bilgileri değerlendirildi.
Bulgular: Çalışma, 218 öğrenci (170 K, 48 E) ile tamamlandı. Çalışmaya, 63 1. sınıf öğrencisi (%28,90), 69 2. sınıf öğrencisi (%31,70), 40 3. sınıf öğrencisi (%18,30), 46 4. Sınıf öğrencisi (%21,10) katıldı. Öğrenciler tarafından en çok tercih edilen Web 2.0 araçlarının sırasıyla YouTube (%97,70), Zoom (%96,80) ve Instagram (%89) oldukları bulundu. Öğrencilerin büyük çoğunluğunun Piktochart (%98,20), Camtasia (%97,20) ve MindMeister (%97,20) araçlarını hiç tercih etmediği bulundu.
Sonuç: Çalışmanın sonucunda fizyoterapi öğrencileri tarafından sırasıyla sosyal medya uygulamalarından Youtube ve Instagram, ders oluşturma uygulamalarından Zoom en çok tercih edilirken, içerik geliştirme/ortak çalışma amacıyla ve çevrimiçi eğitim platformları olarak kullanılan araçların öğrencilerin büyük çoğunluğu tarafından hiç tercih edilmediği bulundu. Bu çalışmadan elde edilen sonuçlar, Fizyoterapi ve Rehabilitasyon öğrencilerinin eğitim süreçlerinde Web 2.0 araçları konusunda farkındalıklarının artırılarak kullanımlarının geliştirilmesi gerektiğini göstermektedir.
Akut pulmoner alevlenme döneminde olan kistik fibrozisli çocuklarda solunum fonksiyonlarının ve fonksiyonel kapasitenin incelenmesi
Authors: Kılıç Kübra , Vardar Yaglı Naciye , Ademhan Tural Dilber , Özsezen Beste , Yalçın Ebru , Sağlam Melda , Çalık Kütükcü Ebru , İnce Deniz , Emiralioğlu Nagehan , Doğru Deniz , Özçelik Uğur , Kiper Nural
Published: November 2024

Amaç: Kistik fibrozis (KF)’li hastalarda akut pulmoner alevlenme döneminde öksürük ve balgam miktarında artış, solunum
fonksiyonlarında azalma görülebilmektedir. Bu çalışmanın amacı, akut pulmoner alevlenme döneminde olan KF’li çocuklarda
solunum fonksiyonlarının ve fonksiyonel kapasitenin incelenmesi idi.
Yöntem: Akut pulmoner alevlenme döneminde olan 18 KF’li çocuk hasta (yaş=12,94±2,57 yıl, 8 kız (%44,4), 10 erkek (%55,6))
çalışmaya alındı. Olguların fiziksel ve klinik özellikleri kaydedildi. Solunum fonksiyonları spirometre ile fonksiyonel kapasite ise
1-dakika otur kalk testi (OKT) ile değerlendirildi.
Bulgular: KF’li çocukların ortalama birinci saniyedeki zorlu ekspiratuar volüm (FEV1) (%) değeri %58,50, zorlu vital kapasite (FVC)
(%) değeri %65,22, tepe ekspiratuar akım hızı (PEF) (%) değeri %62,50 ve zorlu ekspirasyonun ortasındaki akım hızı (FEF%25-75)
(%) değeri %39,77 olarak bulundu. Çocukların hastalık şiddeti sınıflandırmasına göre %77,7’si hafif obstrüktif akciğer
hastalığına sahipti. KF’li çocuklar hastaneye yatış sırasında yapılan 1-dakika OKT’de ortalama 24,88 kez oturup kalktılar ve
beklenilen 1-dk OKT sayısının ortalama %41,87’sine ulaştılar. KF’li çocukların 1- dakika OKT sayısı ile FEV1 (%) (r=-0,041;
p=0,87), FVC (%) (r=-0,085; p=0,73), PEF (%) (r=-0,216; p=0,38) ve (FEF%25-75) (%) (r=-0,215; p=0,39) değeri arasında anlamlı
bir ilişki bulunmadı.
Sonuç: Bu çalışmanın sonucunda akut pulmoner alevlenme döneminde olan KF’li çocukların fonksiyonel kapasitelerinin azaldığı
belirlendi. Ayrıca çocukların büyük çoğunluğunda hafif şiddette obstrüktif akciğer hastalığının görüldüğü saptandı. Akut pulmoner
alevlenme döneminde uygulanacak fizyoterapi ve rehabilitasyon programlarının solunum fonksiyonları ve fonksiyonel kapasiteye
etkisi araştırılmalıdır.
NDM-1 and KPC-3 co-producing Klebsiella pneumoniae ST512 in bronchial secretion from a patient in an intensive care unit of a Greek Tertiary Care Hospital
Authors: Chatzidimitriou Maria , Tsolakidou Pandora , Voulgaridis Apostolos , Kyriazidi Maria Anna , Chatzopoulou Fani , Mavridou Maria , Varlamis Sotiris , Mitka Stella , Vagdatli Eleni
Published: November 2024

This study investigated a strain of Klebsiella pneumoniae, identified as GRTHES, which exhibited extensive antibiotic resistance. The strain was resistant to all beta-lactams, including combinations with newer agents such as meropenem/vaborbactam and imipenem/relebactam, as well as to aminoglycosides, fluoroquinolones, fosfomycin, trimethoprim-sulfamethoxazole and colistin. It remained susceptible to tigecycline. Whole-genome sequencing was performed by Ion Torrent platform on the K. pneumoniae strain. Genomic analysis revealed a genome length of 5,808,650 bp and a GC content of 56.9%. Advanced sequencing techniques and bioinformatic tools were used to assess resistance genes and plasmid replicons, highlighting the emergence of multidrug resistance and virulence traits. The strain carried blaNDM-1 and blaKPC-3 genes and was designated to KL107 O2afg type. Colistin resistance-associated mgrB/pmrB gene mutations were present, and the strain also harbored yersiniabactin-encoding ybt gene. Our findings provide insights into the genomic context of blaNDM-1 and blaKPC-3 carbapenemase-producing K. pneumoniae and emphasize the importance of continuous surveillance and novel therapeutic strategies to combat multidrug-resistant bacterial infections. It is the first time that an NDM-1 and KPC-3 co-producing strain of K. pneumoniae ST512 is identified in Greece. This study highlights the essential role of genomic surveillance as a proactive strategy to control the spread of carbapenemase-producing K. pneumoniae isolates, particularly when key antimicrobial resistance genes, such as blaNDM-1 and blaKPC-3, are plasmid-mediated. Detailed characterization of these isolates could reveal plasmid similarities that facilitate adaptation and transmission within and between hospitals. Although data on patient movements are limited, it is plausible that carbapenem-resistant isolate was selected to co-produce KPC and NDM through plasmid acquisition.
Conhecer para implementar políticas de equidade da participação feminina
Authors: Vidal Irla de Oliveira , Azevedo José Marlo Araújo de , Azêvedo Hellen Sandra Freires da Silva , Souza Tiago Ramos de
Published: November 2024

A pesquisa científica é parte integrante dos Institutos Federais, e a Iniciação Científica (IC) é o primeiro contato para a entrada no mundo da ciência e a formação dos futuros cientistas. Portanto, olhar para esse programa e analisar as políticas de equidade de participação feminina se faz necessário. O objetivo da pesquisa foi analisar o programa de IC do Instituto Federal do Acre (Ifac) discutindo as ações que fomentam a equidade da participação feminina nas ações de pesquisa, inovação e empreendedorismo. O estudo é qualitativo, amparado na pesquisa bibliográfica e documental. Esta pesquisa apresentou indicadores que poderão contribuir na gestão dos programas de pesquisa do Ifac, a partir da compreensão da dinâmica da produção científica dos pesquisadores, docentes, técnicos e alunos.
Ефективність роботи теплових насосів із відбором теплоти від ґрунту та зовнішнього повітря в житлових будинках
Authors: Рєпін Ю.С. , Грищенко С.І. , Климчук Н.В. , Сергеєв М.І. , Ткачов О.А.
Published: November 2024

В роботі проведено аналіз існуючих теплонасосних систем із відбором теплоти від різних джерел, а саме від зовнішнього повітря та ґрунту. Визначені фактори, що впливають на вибір типів теплових насосів в різних комбінованих системах теплопостачання. Охарактеризовані проблеми застосування означених теплових насосів у складі систем теплопостачання для житлових будівель. В роботі представлена математична модель роботи теплового насосу із відбором теплоти від зовнішнього повітря та ґрунту. Для обраних об’єктів дослідження представлені основні технічні характеристики будівель, режими споживання та характеристики різних типів теплових насосів, що працюють у системах теплопостачання вказаних будівель. Протягом року було проведено спостереження за роботою систем теплопостачання із використанням теплових насосів (із відбором теплоти від зовнішнього повітря та ґрунту) для різних видів теплового навантаження (система опалення та система гарячого водопостачання). За отриманими даними побудовано графіки споживання теплоти для потреб опалення та гарячого водопостачання. На основі отриманих даних було розраховано значення коефіцієнту трансформації теплоти та побудовано графіки зміни вказаного коефіцієнту протягом року окремо для теплових насосів із різними джерелами теплоти та за різними видами теплового навантаження. На основі побудованих графіків проведено аналіз ефективності роботи різних типів теплових насосів в залежності від кліматичних чинників та режимів роботи споживання теплоти для вказаних будівель. Отримані результати дозволили оцінити ефективність роботи теплових насосів із відбором теплоти від зовнішнього повітря та теплоти ґрунту протягом року для систем опалення та гарячого водопостачання, що в подальшому буде сприяти розробці комплексних рекомендацій впровадження теплових насосів в системи теплопостачання житлових будівель
Learning how to learn
Authors: Buckoke Peter
Published: November 2024

This is a transcript of the 2021 Memorial Lecture of the Society of Teachers of the Alexander Technique (STAT). The original lecture was presented as a video online. The lecture included excerpts from other video interviews and performances which have not been transcribed. Links to these videos have been included as footnotes in the text. The original presentation can be accessed in full by following the link in the end notes.
Evaluation of School Health Nursing Practice in Acute Health Problems with the Omaha
Authors: Arslan Nesrin , Ardıç Aysun
Published: November 2024

Objective: Healthcare professionals use the Omaha System to diagnose problems in healthy and sick people, identify interventions, and evaluate their outcomes. The main aim of this research was to evaluate the effectiveness of combining the Omaha System-Based Electronic Health Record Program and School Health Nursing Practices in managing acute health issues.

Methods: The data for this study was collected using a retrospective-descriptive approach, using the Nightingale Notes Champ Software and the health infirmary notebook.

Results: The mean age of the participants was 10.30 ± 1.57, with 56.1% being female students. A total of 17 problems were identified and diagnosed 1230 times among the students who visited the health infirmary during the study period. The issues were in the “Physiological” domain 88.9%, Psychosocial” 7%, and “Health Behaviors” 4.1%. The most commonly identified health issues were related to “Skin” 24.2%, “Pain” 20.7%, “Digestive-Hydration” 10.7%, “Circulation” 8.1%, “Oral Health” 7.0%, “Neuromuscular Function” 6.1%, “Mental Health” 5.1%. The Intervention Scheme for the seven most frequent health problems included 17 targets and 1007 nursing interventions, with the Surveillance category being the most commonly used intervention.

Conclusion: The Omaha system has significantly contributed to decision-making based on retrospective data by making intervention processes more systematic in acute health practice in the school environment. As an evidence-based method, the Omaha system supports improving quality and professionalism in school nursing.