bluuebunny/crossref_metadata_2025 huggingface dataset:
Learning from a Post-Typhoon Haiyan/Yolanda Recovery Institution (OPARR): A New Research Agenda for Recovery Governance
Authors: Iuchi Kanako , Jibiki Yasuhito , Tamayose Beth ,   International Research Institute of Disaster Science (IRIDeS), Tohoku University 468-1 Aza-Aoba, Aramaki, Aoba, Sendai, Miyagi 980-8572, Japan,   Next Generation Volcano Researcher Development Program, Tohoku University, Miyagi, Japan,   School of Public Policy, University of California, Riverside, California, USA
Published: November 2020

In the phase after disasters, particularly those of an unprecedented magnitude, governance structures often emerge specifically oriented toward rebuilding, with a post-disaster institution at its center to head the reconstruction process. However, little is understood about such institutions’ actual operation, impact on recovery, and role in recovery governance. As post-disaster institutions are trending in recovery, it is important to better understand their nature. As a first step to comprehending the role of these institutions, this study explores a framework for evaluating their success and unpacking the implications of managing recovery in a compressed timeframe. Methods included literature and ethnographic analysis using first-hand knowledge accumulated through longitudinal in-person interviews. The case institution is the Office of the Presidential Assistance on Reconstruction and Recovery (OPARR), established after the 2013 typhoon Haiyan (local name Yolanda) in the national government of the Philippines. Two major findings are reported: First, seven themes – “establishment,” “funding,” “coordination,” “politics,” “leadership,” “achievement,” and “post-disestablishment” – are identified as useful to assess post-disaster institutions. Second, concepts of permanency versus impermanency of institutions after disasters and bottom-up participatory versus top-down structured processes are identified as key implications of operating recovery under time compression, and as areas for further research. The proposed framework provides a basis to better understand and ultimately improve these institutions’ operation and will ideally further efforts to research cross-comparisons in various locations. The study results also suggest a first step in increasing knowledge toward more effective institutions and refining methodological approaches to better examine institutional operation and recovery governance.
Assessing Flood Risk of the Chao Phraya River Basin Based on Statistical Rainfall Analysis
Authors: Shakti P. C.  , Miyamoto Mamoru , Misumi Ryohei , Nakamura Yousuke , Sriariyawat Anurak , Visessri Supattra , Kakinuma Daiki ,   National Research Institute for Earth Science and Disaster Resilience (NIED) 3-1 Tennodai, Tsukuba, Ibaraki 305-0006, Japan,   International Centre for Water Hazard and Risk Management under the auspices of UNESCO (ICHARM), Public Works Research Institute (PWRI), Ibaraki, Japan,   Mitsui Consultants Co., Ltd., Tokyo, Japan,   Department of Water Resources Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand,   Disaster and Risk Management Information Systems Research Group, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand
Published: November 2020

The Chao Phraya River Basin is one of the largest in Asia and is highly vulnerable to water-related disasters. Based on rainfall gauge data over 36 years (1981–2016), a frequency analysis was performed for this basin to understand and evaluate its overall flood risk; daily rainfall measurements of 119 rain gauge stations within the basin were considered. Four common probability distributions, i.e., Log-Normal (LOG), Gumbel type-I (GUM), Pearson type-III (PE3), and Log-Pearson type-III (LP3) distributions, were used to calculate the return period of rainfall at each station and at the basin-scale level. Results of each distribution were compared with the graphical Gringorten method to analyze their performance; GUM was found to be the best-fitted distribution among the four. Thereafter, design hyetographs were developed by integrating the return period of rainfall based on three adopted methods at basin and subbasin scales; each method had its pros and cons for hydrological applications. Finally, utilizing a Rainfall-Runoff-Inundation (RRI) model, we estimated the possible flood inundation extent and depth, which was outlined over the Chao Phraya River Basin using the design hyetographs with different return periods. This study can help enhance disaster resilience at industrial complexes in Thailand for sustainable growth.
Identidad y fuga. Claves americanas en El turbión de José Luis Acquaroni
Authors: Camacho José Manuel
Published: November 2020

En 1967, el escritor José Luis Acquaroni publicaba su novela El turbión en la que daba buena cuenta de los disturbios sociales originados tras la caída del dictador venezolano Marcos Pérez Jiménez. A partir del error cometido con la identidad de un inmigrante andaluz, llamado Efrén, quien es confundido con uno de los torturadores del régimen, éste se ve obligado a huir durante veinticuatro horas para poner a salvo su vida. En su desplazamiento por la ciudad (trasunto de Caracas) el lector asiste a una ola incontrolada de violencia, con todo tipo de linchamientos, y al saqueo indiscriminado de multitud de negocios y establecimientos comerciales, poniendo al descubierto el lado más sórdido de la sociedad.
Presentación
Authors: Aranda Arribas Victoria , Jiménez Gómez Cristina
Published: November 2020

Presentación de la sección monográfica Literatura y cine, al margen de la adaptación, coordinada y editada por Victoria Aranda Arribas y Cristina Jiménez Gómez.
Image Defogging Algorithm Based on Sky Region Segmentation and Dark Channel Prior
Authors: Jiang Zuyun , Sun Xiangdong , Wang Xiaochun
Published: November 2020

Based on image segmentation and the dark channel prior, this paper proposes a fog removal algorithm in the HSI color space. Usually, the dark channel prior based defogging methods easily produce color distortion and halo effect when applied on images with a large sky area, because the sky region does not meet the prior assumption. For this reason, our method presents a new threshold sky region segmentation algorithm using the initial transmission map of the intensity component I. Based on the segmentation result, the initial transmission map is modified in turn, and finally refined by the guided filter. The saturation components S is reconstructed using the low frequencies of the V-transform to reduce noise, and stretched by multiplying a constant related to the initial transmission map. Experimental results show that the proposed algorithm has low time complexity and compelling fog removal result in both visual effect and quantitative measurement.
The Concept of Multicultural Education in Al-Qur’an Surah Al-Hujarat Verse 11-13
Authors: S Muhammad Tang , Muslimah Muslimah , Riadi Akhmad
Published: November 2020

Many normative basis on multiculturalism exist in the Holy Book of Qor’an. Islamic multicultural education is a solution to the problem of intolerance behavior towards human diversity. This study is discussed the concept of multicultural Islamic education in Surah Al-Hujurat verses 11, 12 and 13 based on both perspective of interpretation of Ibn Kathir's and Al-Misbah's. This study is library study through a thematic approach. The primary data taken from the interpretation of Ibnu Katsir and the interpretation of Al-Misbah. Furthermore, the secondary data were obtained from relevant books and articles. Data were collected through the documentation by collecting, classifying, quoting, checking data related to the study. The instrument of this study is the researcher himself, who acts as a planner, executor, collector, analyzer, and interpreter of the data. Data were analyzed using content analysis methods (hermeneutic interpretation) and maudhu’ i method. There are three fundamental concepts of Islamic multicultural education contained in the Al-Quran surah Al-Hujurat verses 11-13.  The first is to avoid mocking and insulting other people, Secondly, keep away from prejudice and gossipping others, and Thirdly, getting to know each other comes from different tribes, customs, languages, cultures, groups, social status, and even religions by always promoting mutual respect and understanding.
Modeling Process of Forming Flat Surface Tool for Processing Conical Parts
Authors: Kozeruk A. S. , Dias Gonzalez R. O. , Filonova M. I.
Published: November 2020

The relative actuation of the tool is considered, which makes it possible not to take into account the hard-to-determine technological coefficients depending on external conditions, as well as the physical, mechanical and technological properties of the processed material. This response is determined by the distribution of the relative sliding speeds and pressure in the contact zone of the tool and the work-piece, as well as the processing time, which are characterized by the geometric and kinematic parameters of the machine operating mechanism and processing modes. A phased simulation of the actuation process of the tool working surface is proposed: without oscillation of  the upper link and with its return-rotational  movement. According to this approach, at the first stage, the distribution of the relative sliding speeds and pressure in the contact zone of the grinding surfaces is calculated, and at the second stage, when determining the relative response at the points of the lower link (tool), the movement of these points from the areas of the contact zone with same values of the indicated quantities in the area with others is monitored. A mathematical model of the process of shaping a flat surface under conditions of free grinding of the body and counter-body is obtained, which establishes quantitative relationships between the machining modes and the shape of the treated surface and is a simulation numerical model, since it allows to obtain the distribution of relative triggering over the working surface of the tool for pre-selected time points.
Corrosion – Biotechnical System for Destruction of Technical Objects Reducing their Quality and Reliability
Authors: Kudina A. V. , Sokorov I. O.
Published: November 2020

It is a well-known fact, that corrosion of materials, as a phenomenon in the nature, is multifaceted, where its origin and development in many respects depend on environment micro-flora. In the modern world, corrosion is considered mainly as the spontaneous destruction of solids caused by chemical and electrochemical processes, developing on a body surface during its  interaction  with external environment.  The essence  of  corrosion  destruction   of objects  should be studied in aspect  of  the interrelated natural phenomena and processes that constantly occur  when an  object comes into contact with man-made environments and the environment containing many microorganisms of various genera and species. The accumulation and metabolism of microorganisms in surface defects of solids, when favorable physical, chemical and biological conditions are created in the contact zones, create areas of biocenosis in which metabolites, biogenic elements and chemically active radicals are formed, interacting with the contact surface of the body and the technogenic environment. Such interaction gives rise to the occurrence of both biochemical reactions in microbial cells and bioenergetic mechanisms of energy conversion on the contact surfaces, both in the microorganisms themselves and in the surrounding space. This initiator chemical, electrochemical and bio-corrosion processes of materials destruction. Consequently, the phenomenon of corrosion is presented as a system of interrelated microbiological and physicochemical processes of destruction of materials, arising from their interaction with the micro-flora of contact technogenic media and the environment. Based on the generalization and analysis of the results of the performed research work and taking into account the well known achievements and discoveries in the field of science and technology, the authors of the paper propose a new systematic approach and concept to the phenomenon of corrosive destruction of a solid with the account of the biological factor that initiates corrosion damage and destruction of materials.
Thermochemical Preparation and Properties of Low-Cost Polylanthanide Manganite Materials of Ln(La, Ce, Nd, Pr)xCayMnO3-Type with Perovskite-Fluorite Structure
Authors: Gorbunova V. A. , Sliapniova L. M. , Gorbunov A. V.
Published: November 2020

A physical and chemical investigation of ceramic materials based on manganites of mixed rare earth elements  –
Using XlinkCyNET to visualize protein cross-links in Cytoscape software
Authors: Lima Diogo Borges , Zhu Ying , Liu Fan
Published: November 2020

We present a high-performance app for Cytoscape to visualize cross-linking mass-spectrometry (XL-MS) data. XlinkCyNET is an open-source Java plugin that generates residue-to-residue connections provided by XL-MS in protein interaction networks. Importantly, it provides an interactive interface for the exploration of cross-links and offers various options to display protein domains. XlinkCyNET works well in complex networks containing thousands of proteins.
Reduced alpha amplitudes predict perceptual suppression
Authors: Poland Eva , Bhonsle Aishwarya , Steinmann Iris , Wilke Melanie
Published: November 2020

The amplitude of prestimulus alpha oscillations over parieto-occipital cortex has been shown to predict visual detection of masked and threshold-level stimuli. Whether alpha activity similarly predicts target visibility in perceptual suppression paradigms, another type of illusion commonly used to investigate visual awareness, is presently unclear. Here, we examined prestimulus alpha activity in the electroencephalogram (EEG) of healthy participants in the context of a generalized flash suppression (GFS) task during which salient target stimuli are rendered subjectively invisible in a subset of trials following the onset of a full-field motion stimulus. Unlike for masking or threshold paradigms, alpha (8-12 Hz) amplitude prior to motion onset was significantly higher when targets remained subjectively visible compared to trials during which the targets became perceptually suppressed. Furthermore, individual prestimulus alpha amplitudes strongly correlated with the individual trial-to-trial variability quenching following motion stimulus onset, indicating that variability quenching in visual cortex is closely linked to prestimulus alpha activity. We conclude that predictive correlates of conscious perception derived from perceptual suppression paradigms differ substantially from those of obtained with “near threshold paradigms”, possibly reflecting the effectiveness of the suppressor stimulus.
Laughing At, With, About or for? Medical Students' Understanding of Aberrant Humour
Authors: McCreaddie May , Nasser Maryam Jameel
Published: November 2020

Background Humour is a fundamental aspect of communication and is evident in healthcare interactions. Although often perceived as a stable expression of personality in humans, humour is a complex, dynamic, phenomenon and can be rehearsed or spontaneous. A ‘sense of humour’ is generally viewed as a virtuous quality but there are both positive and negative imports to humour use. We explored medical students’ experiences and perceptions of humour use in healthcare settings in the Arabian Gulf.Methods We used a qualitative approach, recruiting a purposive sample of medical students with previous exposure to clinical settings to two audio-recorded focus groups. A previously developed interpretative and illustrative framework was used to interrogate the data using what was known about humour e.g. humour theories and allowing for what was unknown. Data was illustrated via a transcription system that highlighted the prosodical features of speech including how and where humour arose in the interaction. Results The medical student participants provided unprompted examples of humour from their experiences of communication in clinical settings, demonstrating an awareness of humour but with a limited understanding of its import. Aberrant humour - humour that departs from an acceptable standard - a kind of tendentious or superiority humour was most evident creating confusion, doubt and potentially threatening self-worth. At best aberrant humour is non-therapeutic, at worst it is inappropriate and potentially problematic. When medical staff included students in the expression of aberrant humour then students were more likely to justify the practice. Conclusion We demonstrate how a nuanced, ‘layered’ approach to analysing humour events is important in understanding spontaneous humour and making that explicit to others. All medical faculty and students need to be cognisant of humour per se, how it may emerge in nuanced interactions and its subsequent impact upon participants. A starting point for medical curricula could be for example, simple awareness-raising, by applying some aspects of the interpretative and illustrative framework we used to analyse the data reported here.Communication is fundamental to healthcare and humour is an integral part of healthcare work. Consequently, we believe medical education needs to start taking humour seriously.
The Value of Preoperative Urodynamics in Surgery Decision for Pelvic Organ Prolapse Patients with Occult Stress Urinary Incontinence
Authors: Xu Hainan , Xia Zhijun , Hu Qing , Zhao Ying
Published: November 2020

This retrospective cohort study aims to explore the clinical value of urodynamics in evaluating lower urinary tract function in pelvic organ prolapse (POP) patients, and to investigate the urodynamic characteristics of POP patients with occult stress urinary incontinence (OSUI) in whom moderate or above postoperative SUI eventually occurred after prolapse surgery. The medical records of 626 advanced POP patients who underwent vaginal pelvic reconstructive surgery were analyzed. The patients with anterior compartment prolapse were more susceptible to urodynamic changes than those with apical or posterior compartment prolapse (95.1% vs. 40.15%). The proportion of patients with urodynamic abnormality was increased with prolapse severity (68.8% vs. 78.6%). After 3 months, the incidence of moderate or severe postoperative urinary incontinence in the OSUI patients was 20%, while it is 2.8% in non-OSUI patients. In subgroup analysis of OSUI patients, the urodynamics of patients with moderate or above postoperative urinary leakage showed significantly lower Valsalva leak point pressure (VLPP), maximum urethral closure pressure (MUCP), maximal bladder volume (MBV) and maximum urine flow rate (MUFR). For POP patients with OSUI, anti-incontinence surgery is only recommended for whom with lower VLPP, MUCP, MBV and MUFR to avoid the risk and costs of secondary surgery or overtreatment.
Ligand-Dependent Regiodivergent Enantioselective Allylic Alkylations of α-Trifluoromethylated Ketones
Authors: Zhu Yi , Ni Yifan , Lu Chenxi , Wang Xiaochen , Wang Yi , Xue Xiao-Song , Pan Yi
Published: November 2020

The asymmetric introduction of CF3 unit is a powerful tool for modifying pharmacokinetic properties and slowing metabolic degradation in medicinal chemistry. A catalytic and enantioselective addition of α-CF3 enolates allows for expeditious access to functionalized chiral building blocks with CF3-containing stereogenicity. The computational studies reveal that the choice of ligand in a designed palladium-complex system regulates the regioselectivity and stereoselectivity of the asymmetric allylic alkyation (AAA) of α-CF3 ketones and Morita–Baylis–Hillman (MBH) adducts. Multiple C-H···F interactions are involved in the transition states.
Meaningfully Engaging Karen Refugee Families in Physical Activity: The Outcomes of A Culturally Specific, Co-Designed Program
Authors: O'Driscoll Téa , Spaaij Ramón , Borkoles Erika , Polman Remco
Published: November 2020

Background There are numerous health and social benefits of physical activity (PA) participation, yet refugees who have settled into destination countries like Australia are less likely to play sport or exercise, or reach recommended daily PA levels if they do. There may be various correlates of PA which impact on participation, however cultural attributes and the process of cultural adaptation after resettlement, may be a key contributor, impacting on the health of resettlers. This research trialled a community-driven, culturally specific family PA program with Karen refugees settled in Australia. The aims of the program were to encourage participation through a culturally appropriate physical activity setting and provide Karen families with an opportunity to learn to be active together. Methods The grant-funded program consisted of a two-hour lifestyle educational module and a practical activity session held each week for eight weeks, including a six-month follow-up session post completion. Educational sessions covered relevant health topics, such as healthy eating, and practical activity sessions were tailored to meet Karen people’s cultural expectations and needs. All components of the intervention were co-designed with the participants. Results A total of 36 Karen adults and children varying in ages participated in the program, with an average rate of participation of 81.8% over eight weeks. The program was evaluated with surveys, interviews, and informal discussions with instructors and participants, as well as ethnographic methods of observation. Participants valued the program that met their needs. After completion of the program they requested to continue with a similar community-based PA program in the future. Conclusions This culturally appropriate and co-designed PA program effectively engaged Karen people and increased healthy lifestyle behaviours in the group, which they found valuable and meaningful. Future interventions and programs targeting resettled refugees should be co-designed with participants using culturally appropriate approaches.
Increased Expression of Granzyme B and Transforming Growth Factor-β in Intralesional Plasma of Oral Lichenoid Reactions: A Preliminary Study
Authors: Sun Kai , Pan Lei , Deng Yi-wen , Chen Jun , Du Guan-huan , Song Chencheng , Chen Junjun , Han Xiaozhe , Wang Yufeng , Tang Guoyao
Published: November 2020

Background: Oral lichenoid reactions are intractable inflammatory diseases of oral mucosa. The cytokine profiles of intralesional blood remain unclear. We aim at revealing the intralesional cytokine profiles and providing some actual and stable intralesional cytokine biomarkers to evaluate the severity and therapeutic effects of oral lichenoid reactions.Methods: Paired intralesional and peripheral plasma from 26 patients with oral lichenoid reactions were collected. The concentration of 15 cytokines of granzyme B, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL17A, TNF-α, IFN-α, IFN-β, IFN-γ, TGF-β1, TGF-β2 and TGF-β3 was measured by Luminex assays. REU score was used for evaluating the severity of the disease. Results: Eleven cytokines including IL-10, IFN-α, IL-6, IL-17A, granzyme B, TGF-β1, TGF-β2, TGF-β3, IL-2, TNF-α, IL-12p70 were detected within the reliable working range. IL-10 was detected in less intralesional samples (19/26) than peripheral samples (26/26, p=0.01). The cytokine concentrations from intralesional plasma were significantly elevated in granzyme B (median 108.94 vs. 16.00), TGF-β1 (mean 30448.92 vs. 10199.04), TGF-β2 (mean 1659.73 vs. 1308.49) and TGF-β3 (mean 914.33 vs. 573.13) than that in peripheral plasma (p=0.001, p＜0.001, p＜0.001 and p＜0.001, respectively). The concentration of IL-12p70 in peripheral plasma was positively correlated with REU score (coefficient of correlation=0.463, p=0.02).Conclusions: The concentration of granzyme B and TGF-β are more abundant in intralesional microenvironment than in peripheral plasma of oral lichenoid reactions. IL-12p70 may be a potential molecular biomarker for evaluating the severity of oral lichenoid reactions. Cohort study of large population is required.
Enabling visibility of the clinician-scientists’ knowledge broker role in linking research with clinical practice: A participatory design research in the Dutch nursing-home sector
Authors: Barry Margot , Kuijer Wietske , Persoon Anke , Nieuwenhuis Loek , Scherpbier Nynke
Published: November 2020

Background: Twelve clinician-scientists were employed in a Dutch academic network, which is a collaboration between fifteen nursing-homes and an academic medical research institute. The clinician-scientists were tasked with linking research and clinical practice by catalysing both care-informed research and evidence-informed implementation initiatives. The clinician-scientists and their manager experienced difficulties in clearly defining the knowledge broker role of the clinician-scientists, a difficulty also reported in literature. They found no tools and methods suitable for make their knowledge broker role visible. Clarifying role expectations and accountability for funding these knowledge broker positions was difficult. They aimed to design a theory-informed performance appraisal tool that allowed clinician-scientists to explicate and develop their knowledge broker role in collaboration with management.Methods: A participatory design research was conducted over a 21 month period with a design group consisting of an external independent researcher, clinician-scientists and their managers from within the academic network. Results: A tool (the SP-tool) was developed in MS Excel. This allowed clinician-scientists to log their knowledge broker activities as distinct from their clinical work and research related activities. The tool contributed to their ability to make their knowledge broker role visible to themselves and their stakeholders. The theoretic contribution of the design research is a conceptual model of professionalisation of the clinician scientists knowledge broker role. This model presents the relationship between work visibility and the clarification of functions of the clinician-scientist’s knowledge broker role. In the professionalisation of knowledge-intensive work, visibility contributes to the definition of CS broker functions, which is an element necessary for the professionalisation of an occupation.Conclusions: The CSs knowledge broker role is a knowledge-intensive role and work-tasks associated with this role are not automatically visible. The SP-tool contributes to creating work visibility of the clinician-scientists’ knowledge broker role. This in turn could contribute to the professionalisation of this role, which is not well described in literature at the day-to-day professional level.
Prognostic value of thrombin generation parameters in hospitalized COVID-19 patients 
Authors: Morena-Barrio María Eugenia de la , Bravo-Pérez Carlos , Miñano Antonia , Morena-Barrio Belén de la , Fernandez-Perez María Piedad , Bernal Enrique , Gómez-Verdu José Miguel , Herranz María Teresa , Vicente Vicente , Corral Javier , Lozano María Luisa
Published: November 2020

Background. SARS-CoV-2 infection increases the risk of thrombosis by different mechanisms not fully characterized. Although still debated, an increase in D-dimer has been proposed as a first-line hemostasis test associated with thromboembolic risk and unfavorable prognosis. Objective. We aim to systematically and comprehensively evaluate the association between thrombin generation parameters and the inflammatory and hypercoagulable state, as well as their prognostic value in COVID-19 patientsMethods. A total of 127 hospitalized patients with confirmed COVID-19, 24 hospitalized patients with SARS-CoV-2-negative pneumonia and 12 healthy subjects were included. Clinical characteristics, thrombin generation triggered by tissue factor with and without soluble thrombomodulin, and also by silica, as well as other biochemical parameters were assessed.Results. Despite the frequent use of heparin, COVID-19 patients had similar thrombin generation than healthy controls. In COVID-19 patients, the thrombin generation lag-time positively correlated with markers of cell lysis (LDH), inflammation (CRP, IL-6) and coagulation (D-dimer), while the endogenous thrombin potential (ETP) inversely correlated with D-dimer and LDH, and positively correlated with fibrinogen levels. Patients with more prolonged lag-time and decreased ETP presented with increased ISTH-DIC scores, and had more severe disease (vascular events and death). The ROC curve and Kaplan Meier estimate indicated that the D-dimer/ETP ratio was associated with in-hospital mortality (HR 2.5; p=0.006), and with the occurrence of major adverse events (composite end-point of vascular events and death) (HR 2.38; p=0.004).Conclusions. The thrombin generation ETP and lag-time variables correlate with thromboinflammatory markers, and the D-dimer/ETP ratio can predict major adverse events in COVID-19.
A telephone assessment and advice service within an ED Physiotherapy clinic: A single-site quality improvement cohort study
Authors: Kelly Marie , Higgins Anna , Murphy Adrian , McCreesh Karen
Published: November 2020

.BackgroundIn response to issues with timely access for musculoskeletal physiotherapy, telephone assessment and advice services have been evaluated in primary care settings. It is unclear whether this service model can reduce non-attendance rates and wait times and for Emergency Department (ED) physiotherapy, compared to usual care. A secondary aim was to evaluate service user acceptability.MethodsThis was a single-site cohort study that compares data on non-attendance rates, wait time to first physiotherapy contact and participant satisfaction between patients that opted for a service based on initial telephone assessment and advice, versus routine face-to-face appointments. 116 patients were referred for ED physiotherapy over the 3-month pilot at the ED and out-patient physiotherapy department, X, Ireland. 91 patients (78%) opted for the telephone assessment and advice service, with 40% (n=36) contacting the service. 25 patients (22%) opted for the face-to-face service. Data on non-attendance rates and wait time was gathered using the hospital data reporting system. Satisfaction data was collected on discharge using a satisfaction survey adapted from the General Practice Assessment Questionnaire. Independent-samples t-test or Mann Whitney U Test was utilised depending on the distribution of the data. For categorical data, Chi-Square tests were performed. A level of significance of p ≤ 0.05 was set for this study.ResultsThose that contacted the telephone assessment and advice service had a significantly reduced wait time (median 6 days; 3 – 8 days) compared to those that opted for usual care (median 35 days; 19 – 39 days) (p ≤ 0.05). There was no significant between-group differences for non-attendance rates or satisfaction.ConclusionGiven the faster access to ED physiotherapy, without compromising on service user satisfaction, this telephone assessment and advice service, which can be introduced rapidly, could be helpful in triaging referrals and minimising face-to-face consultations in line with COVID-19 recommendations. However, a large scale study is warranted to confirm these findings.
LIGHT CURED RESIN- AN AESTHETIC AND BIOCOMPATIBLE ALTERNATIVE TO CONVENTIONAL DRESSING
Authors: Saxena Dr. Sonal , Punn Dr Karan , Dubey Dr Divya , Srivastava Dr Vivek , Meenawat Dr Ajita , Yadav Dr Shivam
Published: November 2020

Introduction: Periodontal dressings, also known as periodontal packs, have been employed over centuries for the purpose of protection of surgical sites. Many modifications have been made to improve their physical and therapeutic properties. Hence this study was designed to compare and evaluate the clinical efficacy of light cured periodontal dressing to most widely used non-eugenol pack.

Materials and method: Ten patients suffering from generalized chronic periodontitis, requiring periodontal flap surgeries on contralateral sides of the arch were selected and randomly divided into two groups: Group I (Control group) and Group II (Test group). In Group I, non-eugenol periodontal dressing and in Group II light cured periodontal dressing was applied at the surgical sites. Clinical parameters that were assessed on day 7 after the removal of the pack are debris index, plaque scores and gingival index. Patients were also be assessed for acceptance and compliance of the material. All the data recorded was then statistically analysed.

Result: Group II showed better results when compared with the control group on debris index, plaque scores and gingival index, though the differences were found to be statistically insignificant. Group II also showed better results in terms of esthetics, associated mucosal problems, retention of the dressing and over all patient satisfaction.Conclusion: Light cured periodontal dressing showed better patient acceptability and compliance and could be considered to be a clinically efficient and alternative to the non-eugenol pack as the periodontal dressing.
IMPLEMENTATION OF OPTIMUM ADDITIVE TECHNOLOGIES DESIGN FOR UNMANNED AERIAL VEHICLE TAKE-OFF WEIGHT INCREASE
Authors: Maricic Sven , Haber Iva Mrsa , Veljovic Ivan , Palunko Ivana
Published: November 2020

The aim of this paper is to investigate the possibility of drone optimization by selecting and testing the best material suitable for additive manufacturing technology and generative design approach, i. e. shape optimization. The use of additive manufacturing technology enables the creation of models of more complex shapes that are difficult or impossible to produce with conventional processing methods. The complex and unconventional design of the drone body can open up many possibilities for weight reduction while maintaining the strength of the drone body. By using 3D printing in addition to FEM (Finite Element Method) analysis, and generative design it can identify areas of the drone body that are overdrawn, allowing it to either lift off material or simply change the design at these areas. Choosing the right material for this application is crucial in order to optimise the mechanical properties of the material with weight, material cost, printability and availability of the material and the 3D printing method, while at the same time reducing environmental pollution. The goal is to reduce the drone mass by 15–20 % using generative design tools. Mass is an important segment when prototyping a drone. If the drone is too heavy, more lift power is needed to keep the drone in the air, so the propellers have to turn faster and use more energy. Consequently, the reduction of drone mass should increase the take-off weight. In this article 5 commercial drones of similar characteristics are compared with the final proposal of our 3D printed drone (Prototype 1). The rotor distance between the drones, the weight of the electric motor and the take-off weight are compared. The goal was to produce a prototype with a big rotor distance-to-weight ratio, and take-off weight bigger than observed drones have.
The defined goal function was optimized in order to evaluate characteristics of 12 different 3D printed materials. Following properties: ultimate strength, stiffness, durability, printability of the material, and required bed and extruder temperature for printing were taken in consideration to select optimal material. Polycarbonate proved to be the best choice for 3D printing UAVs
STUDY OF THE BEHAVIOURS OF SINGLE-PHASE TURBULENT FLOW AT LOW TO MODERATE REYNOLDS NUMBERS THROUGH A VERTICAL PIPE. PART I: 2D COUNTERS ANALYSIS
Authors: Morad Akeel M Ali , Qasim Rafi M. , Ali Amjed Ahmed
Published: November 2020

This study presents a model to investigate the behavior of the single-phase turbulent flow at low to moderate Reynolds number of water through the vertical pipe through (2D) contour analysis. The model constructed based on governing equations of an incompressible Reynolds Average Navier-Stokes (RANS) model with (k-ε) method to observe the parametric determinations such as velocity profile, static pressure profile, turbulent kinetic energy consumption, and turbulence shear wall flows. The water is used with three velocities values obtained of (0.087, 0.105, and 0.123 m/s) to represent turbulent flow under low to moderate Reynolds number of the pipe geometry of (1 m) length with a (50.8 mm) inner diameter. The water motion behavior inside the pipe shows by using [COMSOL Multiphysics 5.4 and FLUENT 16.1] Software. It is concluded that the single-phase laminar flow of a low velocity, but obtained a higher shearing force; while the turbulent flow of higher fluid velocity but obtained the rate of dissipation of shearing force is lower than that for laminar flow. The entrance mixing length is affected directly with pattern of fluid flow. At any increasing in fluid velocity, the entrance mixing length is increase too, due to of fluid kinetic viscosity changes. The results presented the trends of parametric determinations variation through the (2D) counters analysis of the numerical model. When fluid velocity increased, the shearing force affected directly on the layer near-wall pipe. This leads to static pressure decreases with an increase in fluid velocities. While the momentum changed could be played interaction rules between the fluid layers near the wall pipe with inner pipe wall. Finally, the agreement between present results with the previous study of [1] is satisfied with the trend
PROGNOSIS OF POSTOPERATIVE PROGRESSION OF GLAUCOMA OPTIC NEUROPATHY AT PRIMARY OPEN-ANGLE GLAUCOMA
Authors: Serdiuk Anton
Published: November 2020

Search for new informative markers and methods of prognosis prediction glaucomatous optic neuropathy (GON) in primary open-angle glaucoma (POAG) is an urgent task. We have established efficiency surgical treatment of POAG, but the progression of GON is observed in 10–15 % patients. It is known that the main mechanism of GON is apoptotic death retinal ganglion cells, a marker of which is recognized as tumour necrosis factor-α (TNFα), Fas-ligand (FasL) and a soluble form of the Fas-receptor (sFas/APO-1). The aim of the study: to find out the possibility of using apoptosis factors (TNFα, FasL and sFas/APO-1) to predict postoperative progression of GON at POAG. Methods. 69 patients (69 eyes) with POAG stage I–III were examined, who underwent trabeculectomy with implantation of an Ex-Press shunt. In intraocular fluid (IOF) markers of apoptosis was determined by the method enzyme-linked immunosorbent assay. Repeated ophthalmological examination was performed in 1 year. The control group consisted of 25 patients who were operated on about phacoemulsification of cataracts. For statistical and regression analysis used software package GLZ (Statistica 10, StatSoft, Inc. USA) and module of analysis of operational characteristics of regression models – ROC-diagrams (MedCalc 18.9.1, MedCalc Software, Belgium). Results. Multivariate regression analysis showed that the progression of GON determine the content in IOF of TNFα and sFas/Apo-1 before surgery and intraocular pressure after three months. Based on these indicators, it is calculated satisfactory model of GON progression prediction with 95.4 % accuracy. One-factor logistic regression analysis proved the influence of the content of TNFα, FasL and sFas/Apo-1 for the presence or absence of progression of GON during the year after operations: direct dependence took place for TNFα and FasL and inverse – for sFas/Apo-1. The critical limits of the content in the IOF markers are calculated apoptosis, in which the progression of GON is unmistakably predicted during year after surgery. Conclusions. The obtained results prove the significant influence of the studied markers apoptosis on the progression of GON after surgery. Direct pathogenetic influence belongs to TNFα and FasL.
VALIDATION OF THE SPECTROPHOTOMETRIC PROCEDURE FOR DESLORATADINE ASSAY IN TABLETS APPLYING THE UNCERTAINTY CONCEPT OF THE STATE PHARMACOPOEIA OF UKRAINE
Authors: Leontiev Dmytro , Petrus Vasyl , Volovyk Natalia , Gryzodub Oleksandr
Published: November 2020

Aim. This work aimed to validate an assay procedure for desloratadine tablets by direct spectrophotometric method. Materials and methods. A pilot-scale batch of the pharmaceutical preparation Alerdez, film-coated tablets containing 5 mg of desloratadine, manufactured by PJSC SIC “Borshchahivskiy CPP”, Ukraine, was used as an object of the study. A UV-Vis spectrophotometer Lambda 25 (Perkin Elmer), analytical balance Mettler Toledo XP 205DR, and class A volumetric apparatus were used in the study. Validation of the procedure was performed following the metrological approach of the State Pharmacopoeia of Ukraine (SPhU), whose requirements for the target uncertainty and bias, which rest on the risk assessment of making incorrect decisions on compliance (a confidence level of 95 %), were translated into criteria for all validation characteristics recommended by ICH. All calculations were made in normalised coordinates. The linearity, accuracy and precision (repeatability) were studied in a single experiment using nine different concentrations that uniformly covered the range of ±30 % from the nominal concentration of desloratadine. For validation of the procedure, an SPhU reference standard of desloratadine was used. Results. The experiment design and validation characteristics being tested were in full compliance with ICH Q2(R1) recommendations. All performance characteristics conformed to the criteria recommended by the SPhU. Requirements for the target uncertainty (1.6 %) and bias for any systematic source of variation (≤0.51 %, negligible in relation to 1.6 %) were established. The analytical procedure was specific – the absorbance from the placebo solution was insignificant (A %=0.36). The procedure met the requirements for linearity, accuracy, and precision at the repeatability level. The residual standard deviation s0 was 0.34 (≤ 0.84); correlation index Rc was 0.9998 (≥0.9991); intercept а was 0.045 (less than its confidence interval ∆a=1.14). The confidence interval for recovery ∆Z, which was used as a precision estimate, was 0.55 % (less than the target uncertainty). The mean recovery, which was used as an accuracy estimate, statistically insignificantly deviated from 100% (|Zmean ‑ 100| = 0.022 %).  The confidence interval for the intermediate precision ∆intra was 0.33 % (less than the target uncertainty). The developed analytical procedure was found to be robust. Conclusions. A spectrophotometric procedure suitable for the assay of desloratadine in film-coated tablets Alerdez with content limits of ±5 % was validated by the SPhU approach.
STUDY OF AWARENESS OF PHARMACY EMPLOYEES IN UKRAINE WITH THE PROBLEM OF ANTIBIOTICS RESISTANCE
Authors: Iakovlieva Larysa , Bahlai Tetiana
Published: November 2020

Antibiotic resistance (ABR) is one of today's pressing challenges for scientists, healthcare, and pharmaceutical professionals. Pharmacies are often the first point of patient’s contact with the healthcare system, so the pharmacist must be a source of objective information about ABR and provide qualified advice on prescription and over-the-counter medications. The aim: through questionnaires to identify the level of knowledge about antimicrobial drugs of systemic action in pharmacists and pharmacists in Ukraine, as well as to monitor their behavior on the recommendations and release of antimicrobials without a prescription. Materials and methods. The survey was conducted among pharmacy employees from May 1, 2019, to February 11, 2020. The questionnaire consisted of closed and open questions, multiple-choice, and comparison questions. Results showed high self-esteem of knowledge about antibiotics among respondents, but their answers to open questions indicate a lack of knowledge. Most pharmacists are ready to recommend antibacterial drugs for colds and SARS, whooping cough, sore throat with fever, diarrhea. 69 % of respondents believe that a doctor should prescribe antibacterial drugs, but at the same time, 74 % of respondents do not always or never ask for doctor's prescription for antibiotics. Conclusions. We believe that more articles on antibiotic resistance should be published for pharmacists in order to improve their skills. Issues on this issue should be more actively covered in the curriculum and the process of postgraduate education (training). Pharmacists should also be reminded of the possibility of prescribing over-the-counter medicines to help patients with SARS.
Korištenje interneta u starijoj dobi: je li važno za uspješno starenje?
Authors:   Odjel za psihologiju, Sveučilište u Zadru, Zadar, Nekić Marina , Tucak Junaković Ivana ,   Odjel za psihologiju, Sveučilište u Zadru, Zadar, Ambrosi-Randić Neala ,   Odjel za interdisciplinarne, talijanske i kulturološke studije, Sveučilište Jurja Dobrile u Puli, Pula
Published: November 2020

Internet predstavlja široku arenu mogućnosti u kojoj starije osobe mogu dobiti adekvatnu socijalnu potporu. Strana istraživanja jasno pokazuju da IKT pomaže starijima u održavanju komunikacije s članovima obitelji i prijateljima te da može pomoći i u održavanju psihofizičkog zdravlja. Kako je uspješno starenje višedimenzionalni konstrukt koji uključuje brojne determinante, poput učenja novih stvari, tako korištenje interneta može biti važan čimbenik bolje prilagodbe promjenama koje starenje donosi. Stoga je cilj ovog istraživanja bio utvrditi u kojoj mjeri osobe starije od 60 godina koriste internet i mogu li se individualne razlike u procjeni uspješnosti starenja objasniti korištenjem interneta. U istraživanju je sudjelovalo 295 osoba u dobi između 60 i 89 godina iz različitih županija u Republici Hrvatskoj. Od mjernih instrumenata je korištena Skala samoprocjene uspješnog starenja, dok su ostali konstrukti bili zahvaćeni sa po jednom tvrdnjom, što je slučaj i u drugim sličnim istraživanjima (učestalost korištenja interneta, subjektivna dob, tjelesno i mentalno zdravlje). Dobiveno je da 40% osoba starije životne dobi koristi internet u prosjeku jednom tjedno, i to najviše za potrebe čitanja vijesti i ostalih zanimljivosti kao i za komunikaciju s članovima obitelji i prijateljima. Sudionici koji koriste internet su kronološki mlađi, sebe doživljavaj mlađima, obrazovaniji su, boljeg su tjelesnog i mentalnog zdravlja, i procjenjuju da se bolje prilagođavaju promjenama koje starenje donosi, odnosno da uspješnije stare. Nije utvrđen značajan samostalan doprinos učestalosti korištenja interneta uspješnom starenju, nego je taj odnos posredovan dobrim tjelesnim i mentalnim zdravljem i procjenom sudionika da su mlađi nego što kronološki jesu. Ključne riječi: internet, starije osobe, uspješno starenje