bluuebunny/crossref_metadata_2025 huggingface dataset:
The effectiveness of telemedicine consultation and the elimination of congestion in hospitals
Authors: Alshammari Fawaz Awdah Mohammad
Published: September 2024

Telemedicine can be used in a variety of ways to help hospitals alleviate overcrowding and to reduce high usage of acute care medical resources in hospital settings. None of the interventions reviewed here is mutually exclusive; appropriately, many of them can be used at the same time. It is possible for hospitals to implement a triaging protocol that directs less critical patients to telemedicine. However, the effectiveness of the intervention is limited. In order to be effective, telemedicine must be constructed to fit into broader, existing healthcare systems, and healthcare providers must be trained in how to use and integrate the telemedicine system into their procedures. Given most people's lack of familiarity with telemedicine, as well as a reluctance among the older population to use telemedicine, communities must be reached and patients must be educated about how to use telemedicine. Case studies suggest that telemedicine services in rural areas should strive to meet in person with the patient in order to build confidence in the system before they are used.
Thrombophilia screening in clinical pathology: Guidelines and controversies
Authors: Almuhaysh Maryam Ahmed , Alsadun Jawaher Sadun , Almulhim Munirah Mohammed , Almousa Maryam Mousa Ahmed , Hadadi Ali Moharag , Aljaafari Ola Abdullah , Alhussain Ali Hassan , Alquwayi Waseem Ali , Alkuwaiti Yasser Abdrab Alameer , Almehainy Ahmed Mohammed
Published: September 2024

Background: Thrombophilia screening is crucial in assessing the risk of venous thromboembolism (VTE), particularly in patients with a history of VTE. Clinical guidelines recommend targeted testing based on management implications and clinical context, including factors like surgery, malignancy, and hormonal status. Aim: This review evaluates the significant laboratory factors affecting the interpretation of thrombophilia test outcomes, specifically focusing on inherited and acquired thrombophilias associated with VTE. Methods: The review discusses common thrombophilias, including factor V Leiden, prothrombin mutations, deficiencies in protein C, protein S, and antithrombin, as well as antiphospholipid antibodies. It emphasizes pre-analytical variables influencing diagnostic accuracy and describes recommended laboratory protocols for specimen collection, processing, and testing. Results: Key findings indicate that genetic mutations and deficiencies significantly elevate VTE risk in various populations. The accuracy of functional assays is influenced by factors such as specimen handling, anticoagulant therapy, and the presence of interfering substances. Conclusion: Proper interpretation of thrombophilia testing is essential for effective patient management. Understanding the impact of laboratory variables is crucial for minimizing diagnostic errors and ensuring accurate assessment of thrombotic risks.
IDENTIFIKASI MERKURI (Hg) PADA HANDBODY LOTION RACIKAN YANG DIPERJUALBELIKAN DI KOTA MAKASSAR
Authors: Mardiah Mardiah
Published: September 2024

Handbody Lotion merupakan salah satu jenis kosmetika yang berbentuk lotion yang sering digunakan untuk membuat kulit tetap lembab dan harum semerbak sepanjang hari. Seiring dengan banyaknya permasalahan kulit seperti kulit gelap dan kering, saat ini telah hadir handbody lotion pemutih racikan yang segaja dirancang khusus untuk memutihkan kulit gelap dan mengatasi masalah kulit kering karena pengaruh paparan sinar matahari, karena itu konsumen harus berhati-hati dalam memilih kosmetik pemutih, karena tidak semua produk pemutih yang beredar di masyarakat aman untuk dikonsumsi. Tujuan penelitian ini untuk mengetahui ada tidaknya kandungan merkuri (Hg) yang terdapat pada Handbody Lotion racikan yang diperjualbelikan di Kota Makassar. Penelitian ini bersifat observasi laboratorik, dengan 10 sampel Handbody Lotion racikan. Sampel dikumpulkan dari masyarakat yang menjual Handbody Lotion racikan di Kota Makassar. Pada penelitian ini data yang diperoleh disajikan dalam bentuk tabel disertai narasi. Identifikasi merkuri diperiksa dengan metode kualitatif. Dari hasil penelitian yang telah dilakukan, menggunakan uji kualitatif menunjukkan pada 10 sampel yang diperiksa, 2 (20%) sampel mengandung merkuri (Hg) dan 8 (80%) sampel tidak mengandung merkuri (Hg), ditandai dengan terbentuknya endapan pada filtrat setelah penambahan pereaksi.
PEMERIKSAAN KADAR KREATININ DARAH PADA PETANI PENGGARAP SAWAH DI KECAMATAN SANROBONE KABUPATEN TAKALAR
Authors: Rasiyanto Effendy , Rauf Muhammad Mirwan
Published: September 2024

Penelitian ini berlatar belakang manusia dalam kesehariannya sering mengabaikan kesehatan dikarenakan kesibukan akan pekerjaan. Petani sawah merupakan suatu pekerjaan yang membutuhkan kekuatan fisik dalam bekerja, salah satu kegiatannya yaitu mencangkul dan mengangkat gabah hasil panen padi yang dilakukan dalam jangka waktu yang cukup lama, sehingga memiliki resiko tinggi terjadinya cedera pada anggota tubuh ataupun pada otot rangka. Kreatinin merupakan produk kreatin otot yang merupakan hasil akhir metabolisme otot yang di lepaskan oleh otot dan ditemukan pada otot rangka, kemudian diekskresikan oleh ginjal melalui kombinasi filtrasi dan sekresi, konsentrasinya relatif konstan dalam darah dari hari kehari, kecuali jika terjadi kerusakan otot. Penelitian ini bertujuan untuk mengetahui gambaran hasil pemeriksaan kadar kreatinin darah pada petani sawah. Manfaat pada penelitian yaitu untuk mengaplikasikan ilmu yang telah diperoleh selama masa perkuliahan, sebagai acuan untuk peneliti selanjutnya dan sebagai informasi bagi masyarakat tentang betapa pentingnya pemeriksaan kreatinin darah. Metode yang digunakan dalam penelitian yaitu metode Jaffe reaction dengan menggunakan alat Siemens Dimension EXL 200 Chemistry System. Hasil penelitian ini menunjukkan bahwa, dari 10 sampel serum yang diperiksa diperoleh hasil yang normal, walaupun 8 dari 10 sampel tersebut memiliki kadar kreatinin darah diatas 1 mg/dl namun masih dalam batas normal. Sebagai kesimpulan pada penelitian ini bahwa dari 10 sampel serum yang diambil pada petani sawah memiliki kadar kreatinin darah yang masih dalam batas normal.
UJI DAYA HAMBAT EKSTRAK DAUN AVOCAD TERHADAP PERTUMBUHAN Staphylococcus aureus
Authors: Hardiyanti Hardiyanti , Basarang Mujahidah , Irwan Andi Yunita
Published: September 2024

Salah satu permasalahan kulit yang sering muncul adalah jerawat. Peradangan yang terjadi pada jerawat dapat dipicu oleh bakteri salah satunya bakteri Staphylococcus aureus. Salah satu tanaman herbal yang dapat digunakan untuk pengobatan jerawat adalah daun avocad (Persea americana Mill). Daun avocad mengandung senyawa aktif seperti flavonoid, polifenol, saponin, tanin, dan alkaloid sebagai antibakteri yang dapat menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui kemampuan ekstrak daun avocad dalam menghambat pertumbuhan Staphylococcus aureus dengan menggunakan metode difusi agar berlapis dan menggunakan penicillin G sebagai kontrol positif. Selanjutnya diukur zona hambat yang terjadi pada beberapa seri konsentrasi daun avocad (25%, 50%, 75%). Hasil pengukuran zona bening didapatkan diameter rata-rata pada konsentrasi 25% sebesar 14,7 mm, 50% sebesar 15,8 mm dan 75% sebesar 16,7 mm dan kontrol positif 20 % sebesar 33,2 mm. Hasil evaluasi menunjukkan bahwa zona hambat yang paling baik adalah konsentrasi 75%. Penelitian ini menunjukkan bahwa ekstrak daun avocad pada konsentrasi 25%, 50%, dan 75% mampu menghambat pertumbuhan Staphylococcus aureus.
MULTIPLEX PCR UNTUK MENDETEKSI Candida Spp
Authors: Anita Anita , Maidin Asaad , Massi Nasrum
Published: September 2024

Candida spp merupakan infeksi jamur tersering pada manusia yang dapat menyebabkan infeksi primer dan sekunder pada penderita tuberkolosis paru. Penelitian ini bertujuan untuk mengukur keakuratan (sensitifitas dan spesifitas ) Multiplex PCR untuk mendeteksi Candida spp. Desain penelitian adalah observational studi dengan jumlah sampel 55 sputum BTA positip yang dipilih berdasarkan propotional ramdoms sampling. Pengambilan sputum, data faktor biomedis meliputi: umur, jenis kelamin, riwayat tentang penyakit tuberkulosis, riwayat penyakit lainnya, riwayat pengobatan dikumpulkan oleh petugas laboratorium yang terlatih. Analisis data digunakan untuk mengukur sensitifitas dan spesifitas Multiplex PCR untuk mendeteksi Candida spp. Hasil penelitian menunjukkan bahwa kelompok umur 29-33 tahun dan 40-45 tahun memiliki resiko terinfeksi oleh jamur Candida spp, sebanyak 7 orang (20%). 6 orang (17.1 %) laki-laki dari kelompok umur 29-33 tahun dan 1 orang (2.8 %) dari kelompok umur 40-45 tahun sedangkan untuk perempuan terdapat 3 orang (8.5 %) dari kelompok umur 46-51 tahun memilki resiko untuk terinfeksi jamur Candida spp.Untuk Multiplex PCR memiliki sensitivitas dan spesifitas yaitu 100%. Multiplex PCR mendeteksi Candida albicans, Candida krusei, Candida parapsilosis, Candida tropicalis, dan Candida dubliniensis. Dari penelitian ini dapat disimpulkan bahwa untuk mendeteksi Candida spp dari sputum pasien tuberkulosis dapat menggunakan Multiplex PCR yang merupakan metode identifikasi yang sensitif, akurat, dan cepat. Oleh karena itu kami menyarankan untuk dilakukan penelitian tentang identifikasi Candida spp dari berbagi sumber specimen.
PENGARUH PENUNDAAN SAMPEL URINE PADA PEMERIKSAAN GLUKOSA URINE METODE BENEDICT TERHADAP PENDERITA DIABETES MELLITUS TIPE 2
Authors: Arisanti Dewi , Azis Nurul Ni'ma , Kasmirati Kasmirati
Published: September 2024

Penelitian ini dilatar belakangi karena seringnya terjadi penundaan pemeriksaan urine yang dapat mempengaruhi hasil pemeriksaan glukosa urine yang disebabkan oleh meningkatnya jumlah bakteri. Tujuan penelitian ini adalah untuk mengetahui ada tidaknya pengaruh penundaan kadar glukosa urine pada penderita Diabetes Mellitus tipe-2. Penelitian ini merupakan penelitian eksperimen laboratorik dimana sampel yang digunakan sebanyak 20 sampel dengan teknik pengambilan sampel secara accidental sampling. Setelah dilakukan pemeriksaan terhadap pasien Diabetes Mellitus tipe 2 sebanyak 20 sampel, didapatkan 3 sampel yang normal dengan kode sampel U14, U16 dan U17 meski telah dilakukan penundaan pada pemeriksaan dan 17 sampel menunjukkan hasil yang meningkat dengan kode sampel U1, U2, U3, U4, U5, U6, U7, U8, U9, U10, U11, U12, U13, U15, U18, U19 dan U20 setelah dilakukan penundaan pemeriksaan urine. Dari hasil penelitian menggunakan uji ANOVA didapatkan hasil 0,009 < 0,05. Maka dapat disimpulkan bahwa terdapat pengaruh yang signifikan pada penundaan sampel urine 30 menit dan 60 menit pada pemeriksaan glukosa urine metode benedict terhadap penderita Diabetes Mellitus tipe 2
Aspergillus sp PADA PISANG SALE YANG DIPERJUALBELIKAN DI KOTA MAKASSAR
Authors: Basarang Mujahidah , Zainuddin Erna Adriana
Published: September 2024

Pisang merupakan salah satu komoditas yang melimpah sepanjang tahun di Indonesia, namun seringkali produksinya tidak mampu diserap oleh pasar. Untuk mengatasi hal tersebut masyarakat secara tradisional mengawetkan pisang dengan mengolahnya melalui cara pengeringan di bawah sinar matahari. Hasil olahan ini dinamakan pisang sale. Proses pembuatan pisang sale dengan teknik pengeringan memiliki banyak faktor resiko kontaminasi mikroorganisme seperti jamur melalui udara yang mengandung spora. Hal ini didukung oleh komposisi pada pisang sale yaitu glukosa, protein dan karbohidrat. Sehingga pisang sale dapat terkontaminasi oleh jamur seperti Aspergillus flavus dan Aspergillus fumigatus. Jamur inimerupakan jamur penghasil aflatoksin terbesar di dunia. Tujuan dari penelitian ini adalah untuk mengidentifikasi Aspergillus flavus dan Aspergillus fumigatus pada pisang sale yang diperjualbelikan di Kota Makassar. Berdasarkan hasil penelitian yang telah dilakukan di Laboratorium Science Building Universitas Hasanuddin Makassar dari 5 sampel pisang sale yang dikumpulkan secara random sampling diidentifikasibeberapa jenis jamur, yaitu ditemukan koloni khamir dan penicilium sp pada sampel A, ditemukan koloni khamir pada sampel B, ditemukan koloni khamir pada sampel C, ditemukan Rhizopus sp pada sampel D, sedangkan sampel E ditemukan Aspergillus fumigatus. Dari penelitian ini dapat disimpulkan bahwa dari 5 sampel pisang sale yang dikumpulkan dari pasar tradisional kota Makassar hanya satu sampel positif Aspergillus fumigatus.
KONSENTRASI AIR JERUK PERAS (Citrus sinensis) PENGGANTI ASAM LARUTAN TURK UNTUK HITUNG JUMLAH LEUKOSIT
Authors: Rahmayanti Rahmayanti , Wahab Irwana , Fajarna Farah , Nazir Nazir
Published: September 2024

Pemeriksaan hitung jumlah leukosit manual biasanya menggunakan larutan Turk dengan komposisi asam asetat glasial, gentian violet dan aquadest. Larutan Turk secara umum berfungsi sebagai pengencer dan melisiskan sel-sel selain leukosit. Jeruk peras (Citrus x sinensis) memiliki kandungan asam sitrat yang sifat keasamannya hampir sama dengan asam asetat yaitu mempunyai sifat keasaman lemah yang dapat dijadikan pengganti asam asetat pada komposisi larutan Turk. Tujuan penelitian yaitu untuk mengetahui variasi konsentrasi air perasan jeruk peras (Citrus x sinensis) pada konsentrasi 2%, 3%, 4% dan 5% sebagai pengganti asam pada komposisi larutan Turk dalam hitung jumlah leukosit. Penelitian ini bersifat penelitian dasar murni (basic research) yang laboratorik dan dilaksanakan pada bulan Oktober 2023 di Laboratorium Patologi Jurusan Teknologi Laboratorium Medis Poletekkes Kemenkes Aceh menggunakan teknik purposive sampling. Pengumpulan data dilakukan dengan cara deskriptif yaitu dengan cara membuktikan berapa persen konsentrasi efektif digunakan untuk hitung jumlah leukosit, lalu data disajikan dalam bentuk tabulasi. Setelah dilakukan penelitian diperoleh bahwa variasi konsentrasi air perasan jeruk peras (Citrus x sinensis) dapat digunakan sebagai bahan alternatif pengganti komposisi larutan Turk untuk hitung jumlah leukosit dan efektif pada semua konsentrasi 2%, 3%, 4% dan 5%, namun jumlah leukosit yang paling banyak diperoleh pada konsentrasi 2% dimana inti leukosit terlihat jelas dan mudah untuk dihitung.
ANALISIS HASIL KONTROL KUALITAS PEMERIKSAAN HEMOGLOBIN DAN HEMATOKRIT
Authors: Wulandari Elsa , Astuti Tri Dyah , Hadi Wahid Syamsul
Published: September 2024

Untuk menjamin hasil pemeriksaan yang benar, mekanisme kontrol yang dikenal sebagai aktivitas pemantapan mutu internl (PMI) diterapkan untuk menghindari atau menghilangkan kesalahan dan penyimpangan. Secara khusus, laboratorium sering melakukan uji hemoglobin dan hematokrit. Hematology Analyzer otomatis yang digunakan untuk pengujian ini berpotensi memberikan hasil pembacaan hematokrit dan hemoglobin dengan kesalahan pembacaan. Untuk menjamin hasil yang tepat, prosedur kontrol kualitas dapat mengidentifikasi kesalahan ini. Hasil kontrol kualitas hemoglobin dan hematokrit, termasuk presisi dan akurasi, serta bagan kontrol Levey-Jennings, aturan Westgard, dan nilai metrik sigma, menjadi fokus investigasi ini. Data sekunder dari pemeriksaan kontrol kualitas harian hemoglobin dan hematokrit yang dilakukan dengan Hematology Analyzer Mindray BC-6200 dan bahan kontrol komersial pada tingkat normal pada bulan Januari, Februari, dan Maret 2024 digunakan dalam penelitian ini, yang menggunakan metode deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa pemeriksaan hematokrit memiliki nilai bias sebesar 2,08%, -0,13%, dan 0%, sedangkan pemeriksaan hemoglobin memiliki nilai bias sebesar 0,16%, 0%, dan 0,41%. Untuk pemeriksaan hemoglobin, CV sebesar 0,57%, 0,65%, dan 0,57%; untuk pemeriksaan hematokrit sebesar 1,08%, 0,87%, dan 0,79%. Hasil perbandingan grafik Levey-Jennings dengan aturan Westgard menunjukkan bahwa nilai kontrol—khususnya, 12s, 13s, dan 22s—melebihi ketentuan Westgard. Pemeriksaan hematokrit memiliki nilai metrik sigma lebih dari 4, dan pemeriksaan hemoglobin memiliki nilai metrik sigma lebih besar dari 6. Ini menunjukkan bahwa kedua tes tersebut memiliki kualitas yang baik, dengan pemeriksaan hemoglobin memiliki kualitas yang lebih tinggi dimana nilai sigma yang lebih tinggi menunjukkan variasi yang lebih kecil dan kualitas yang lebih baik.
Study on Performance Simulation Matching of One-Dimensional Hydrogen Storage and Supply System for Hydrogen Fuel Cell Vehicles
Authors: Liu Qi , Xiong Biao , Liu Yuxuan , Zhang Chuanyu , Yuan Shuo , Ma Wenshang
Published: September 2024

Article
Study on Performance Simulation Matching of One-Dimensional Hydrogen Storage and Supply System for Hydrogen Fuel Cell Vehicles

Qi Liu 1,2, * , Biao Xiong 1,3, Yuxuan Liu 1,3, Chuanyu Zhang 1,3, Shuo Yuan 1,2, and Wenshang Ma 1,3

1 College of Mechanical and Vehicle Engineering, Hunan University, Changsha 410082, China
2 Research Institute of Hunan University in Chongqing, Chongqing 401120, China
3 State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body, Hunan University, Changsha 410082, China
* Correspondence: author: hnuliuqi@hnu.edu.cn

Received: 1 July 2024; Accepted: 12 September 2024; Published: 27 September 2024

Abstract: With the improvement of environmental protection requirements, hydrogen fuel cell vehicles are considered one of the most potential and promising new energy vehicles because of their advantages, such as pollution-free emission, long cruising range, and short hydrogenation time. However, there are still unresolved problems between the storage and supply of hydrogen and the power demand during the operation of hydrogen fuel cell vehicles. In this study, a hydrogen fuel cell vehicle is taken as the research object, and a one-dimensional model is built according to the basic performance parameters so as to explore the operation law of the power performance demand of the hydrogen fuel cell vehicle, simulate the power demand in the actual operation process, summarize the influence of different parameters on the power economic performance of the vehicle, and put forward optimization strategies to improve the power, durability, and fuel economy of the vehicle.
Oncolytic Viruses: From Basics to Challenges to Innovation
Authors: S. Haidar Ziyad
Published: September 2024

The landscape of cancer therapeutics has undergone a transformative shift from broad approaches, such as radiation and chemotherapy, to more precise strategies, encompassing small molecule kinase inhibitors and monoclonal antibodies targeting immune checkpoint molecules. Oncolytic viruses (OVs) have recently emerged as a promising and viable option for cancer immunotherapy, particularly for “cold” tumors entrenched in an immunologically-suppressive tumor microenvironment. Genetic attenuation refines the characteristics of OVs, replacing specific genes to enhance conditional viral replication within tumor cells. Despite their potential, the therapeutic use of OVs faces challenges such as pre-mature elimination by the immune system of the host alongside the dense stromal barriers. In this review article, the strategic encapsulation of genetically-engineered OVs within intra-lesional/-tumoral carriers/ vehicles such as mesenchymal stem cells are explored. To further enhance vector delivery strategies and precise targeting, protecting/shielding OVs from host immune responses, via utilizing release-controlled nanoparticles and employing nanofilaments to optimize vector propagation, for example, are discussed. Such innovative approaches not only mitigate challenges related to pre-mature viral clearance and stromal barriers yet also facilitates a localized, controlled, and sustained release of OVs, thereby optimizing their therapeutic bio-safety and -impact. Ongoing clinical investigations are exploring the synergies between OVs and carriers/delivery systems, combined with various anti-cancer therapeutics as radiotherapy, chemotherapy, immune checkpoint inhibitors, and monoclonal antibodies. These studies hold promise for revolutionizing cancer treatment, ensuring both safety and efficacy, aiming to advance bio-pharmaceutical delivery systems from bench-top to bed-side for enhanced therapeutic results, improved patient survival, and enhanced quality of life or QoL.
PROBLEMS AND PROSPECTS OF GRAIN AERATION TECHNOLOGIES
Authors: Drincha V.M. , Dondokov Yu.Zh. , Ammosov I.N. , Alesksandrov N.P. , Mashiev Ch.G.
Published: September 2024

The article analyses grain bulk, being man-made ecological system, where biotic components and their abiotic environment interact with each other. The article determines physical properties of grain bulks and air flow underlying grain aeration processes. It summarizes and classifies technological problems of grain safety which can be solved by aeration. It reveals significant problems associated with increasing preservation of freshly harvested grain. The problem is the presence of small and light impurities in grain mass, which are source of harmful microorganism concentration. The study reveals the main problems of grain aeration drying with additional heating of atmospheric air and presents their possible solutions. Aeration rate limit values are given for performing the main technological operations of grain safety. The article demonstrates importance of grain hygroscopic properties for its aeration, and moisture movement balance at different values of water vapor partial pressures in air and grain.
FOOD FIBERS IN PRODUCTION OF CHOPPED MEAT SEMI-FINISHED PRODUCTS
Authors: Syarova L.N. , Zabalueva Yu.Yu. , Ivanova N.G. , Danilova L.V.
Published: September 2024

Quality of life, working capacity and longevity depend on what a person eats. Meat is one of essential nutritional factors, but it lacks carbohydrates. Dietary fiber is known to be important for prevention of human diseases (diabetes, obesity, cancer, cardiovascular diseases), therefore, recipes for meat products with food fiber are currently being developed. The article presents developed recipes for semi-finished minced meat products from poultry with the introduction of natural dietary wheat fibers «Unitsel VF 200» in place of the chicken fillet part. The study of functional, technological and organoleptic properties of experimental minced meat samples with additive «Unitsel VF 200» made it possible to obtain product containing complex of all nutritional elements, including proteins, fats, carbohydrates, dietary fiber, while meeting the necessary sensory characteristics. The optimal amount of added wheat fibers «Unitsel VF 200» to the composition of minced poultry meat was 24 % in dry form, 510 % in hydrated form.
INFLUENCE OF ADDITIVES WITH VARIOUS ACTION SPECTRUM ON CONCRETE MIXTURE HEAT GENERATION IN TRANSPORT CONSTRUCTION
Authors: Pulyaev I.S. , Aleksandrova O.V. , Pulyaev S.M. , Manyukov A.S.
Published: September 2024

The article deals with topical issues of heat generation processes in concrete mixtures made with additives of various origins and action spectrums (mainly plasticizing and hyper plasticizing) in transport construction. They are widely used in recent years, as well as modifiers based on micro silica. The paper presents analysis of existing methods for determining the hydration heat of Portland cement. It demonstrates rationale principle scheme of the automated calorimetric unit, which gives the most accurate measurement results of changing compositions of concrete mixture and has found wide application in practice. The article demonstrates results of heat generation in concrete mixes based on cement binders prepared with plasticizers, a hyperactive plasticizer based on polycarboxylate and a concrete mix with the MB-10-01 modifier. The study shows expediency of such tests in approbation and implementation of high-grade concrete mixtures with modern additives. They have direct impact on the processes occurring in hardening concrete as well as the need to take into account the obtained data in process of designing and constructing transport infrastructure facilities for various purposes.
FERROUS QUARTZITE BENEFICATION WASTE AS STRUCTURAL COMPONENT OF FINE-GRAINED CONCRETE
Authors: Makeev A.I.
Published: September 2024

The article describes problematic situation with waste accumulation from iron ore concentrate production (beneficiation tailings) from ferruginous quartzite at JSC Olkon (Murmansk Region). The task is to utilize beneficiation tailings as a fine-grained concrete component. The paper presents results of beneficiation tailings diagnostics and their testing as a part in the processes of fine-grained concrete structure formation in comparison with quartz sand from the Olenegorsk quarry. According to the research, the replacement of natural sand with beneficiation tailings in their original form leads to a decrease in strength due to insufficient compaction of mixture under adopted vibration compaction modes. At the same time, the use of ground beneficiation tailings in binder composition ensures increase in strength of concrete compared to concrete on "pure" cement and increase of efficiency by using clinker part of binder in formation of concrete strength by 57-58%. The study recommends the use of fine-grained concrete composition of class B40 for production of vibration-pressed urban land improvement products (paving slabs, curbstones, etc.). It reveals prospects for further research in construction and technological utilization of ferruginous quartzite enrichment tailings as a factor in the formation of biosphere-compatible living environment in the region.
INTERCONNECTION OF HIGH-STRENGTH CERAMIC PROPERTIES WITH MICROSTRUCTURE AND PHASE COMPOSITION
Authors: Khorina A.V. , Shelkovnikova T.I.
Published: September 2024

The article investigates interconnection of high physical and mechanical characteristics of highstrength building ceramics and phase composition of ceramic shard. The authors identify phase composition and microstructure of clinker brick and porcelain stoneware samples by powder X-ray diffraction and using a scanning electron microscope. The shard structure affects many properties of products, including strength, water absorption, frost resistance, etc. The article considers components of building ceramics microstructure, which give high physical and mechanical characteristics to product. High physical and mechanical properties of clinker bricks are achieved due to the content of needle-shaped mullite. The microstructure of clinker bricks is represented by fused quartz grains and mullite crystals with glass interlayers between them. In porcelain stoneware, fine-crystalline mullite is distributed in the X-ray amorphous phase. Porcelain stoneware has a welldeveloped X-ray amorphous phase due to intensive liquid-phase sintering. In samples of high-strength building ceramics the study establishes leucite crystals formation, having reinforcing effect on structure of a ceramic shard.
INFLUENCE OF INCINERATION ASH AND SLAG WASTE IMPURITIES ON THERMAL CONDUCTIVITY OF MINERAL BASALT WOOL
Authors: Shishulkin S.Yu. , Starinskiy I.V. , Tran Ph.L. , Shaidorov A.A.
Published: September 2024

Basalt fibers are material with unique combination of good mechanical and operational properties at relatively low cost. These properties of basalt fibers are actively used in construction industry to create fibrous thermal insulation materials using both pure basalt and its mixture with other materials. This article examines the effect of ash and slag waste from waste incineration plants on thermal conductivity coefficient and suitability of mixture of basalt with ash and slag waste for production of high-quality fibrous thermal insulation materials. The melt was prepared in plasma energy reactor, with subsequent drawing of mineral fibers on original installation. Resulting mineral fibers were examined to determine thermal conductivity according to standard technique. The study also determined elemental composition of fibers and their average diameter and assessed change in original composition of charge and mineral fibers.
Optimization of molar concentrations for enhanced crystallinity and bandgap tuning of ZrO2 thin films via spray pyrolysis for advanced optical applications
Authors: Chaouch Nadjat , Nadjette Belhamra , Sahnoune Derradji , Azzeddine Charef , Sbaihi Amira , Said Benramache , Benbrika Chaima
Published: September 2024

In this study, Zirconium oxide (ZrO2) thin films were synthesized on glass substrates at 400°C using the Spray Pyrolysis method, due to its simplicity, cost-effectiveness, and precise control. The films were prepared at varying molar concentrations (0.1, 0.15, and 0.2 M) and analyzed for their structural, optical, and morphological properties. X-ray diffraction (XRD) confirmed that all films exhibited a tetragonal crystalline structure with a preferred orientation along the (101) plane. The crystallite size, calculated using the Scherrer equation, reached a maximum of 27.26 nm at 0.2 M concentration, indicating improved crystallinity with higher concentration. Optical studies revealed a decrease in transmittance and an increase in absorbance in the visible region as the concentration increased, accompanied by a reduction in the optical band gap from 3.84 to 3.57 eV and an increase in Urbach energy. Scanning Electron Microscopy (SEM) images showed that the films had a dense and smooth morphology, while Energy Dispersive X-ray (EDX) analysis confirmed the elemental presence of zirconium and oxygen in the films.
Analysis of ALDOC Expression and Prognostic Value in Acute Myeloid Leukemiahe
Authors: Huang Jianwei
Published: September 2024

Objective: This study aimed to investigate the expression pattern of ALDOC in patients with acute myeloid leukemia (AML) and to assess its potential as a prognostic marker. Methods: Data for this study were derived from the public databases TCGA and GTEx. Based on the expression levels of ALDOC in different age groups, the impact of ALDOC expression on the prognosis of AML patients was evaluated using univariate and multivariate Cox regression analyses, in conjunction with Kaplan-Meier survival curves. Bioinformatics methods were also employed to explore the possible mechanisms of ALDOC action in AML. Results: A significant difference in the expression of the metabolic gene ALDOC was found between AML patients and normal individuals (P < 0.05). ALDOC was identified as a prognostic marker for patients under the age of 60. Bioinformatics analysis suggested that high expression of ALDOC could upregulate pathways involved in allograft rejection, response to IFN-α, response to IFN-γ, and phagocytosis, particularly indicating a poorer prognosis in patients under the age of 60. Conclusion: High expression of ALDOC is associated with poor prognosis in AML patients under the age of 60, and ALDOC may serve as a marker for AML prognosis and a promising potential therapeutic target for further research.
The Application and Potential Future Development of Artificial Intelligence in Education
Authors: Xu Haimo
Published: September 2024

With the coming of the era of artificial intelligence, the impact of artificial intelligence technology on basic education has been widely discussed, but there are still many problems and challenges. This paper focuses on the analysis of AI technology enabling basic education and the challenges in the application process. This paper concludes that artificial intelligence helps teachers carry out intelligent teaching and promotes students' personalized learning. But at the same time, AI also brings many challenges and risks, such as how to protect privacy and filter information in data overflow; And how to keep students creative while using AI. Based on this, this paper puts forward the following suggestions: the government should strengthen the investment and optimize the allocation of basic education resources; The government will explore the development of ethical norms and regulatory mechanisms applicable to artificial intelligence in the field of education; Schools to strengthen the training and introduction of teachers; Individual students combine artificial intelligence with real life.
Snyder Hopes the Application of Theoretical Model of Nursing Intervention in Patients with Brain Malignancy Surgery
Authors: Zhang Liying , Yang Changmei
Published: September 2024

Explore the application value of nursing intervention based on Snyder hopes theory in patients with brain malignancy surgery. Methods The 110 cases of patients with brain malignancy who were treated in our hospital from January 2023 to January 2024 were selected as a study object. They were randomly divided into observation group and control group. The control group was received routine nursing. The hope theoretical intervention was performed on this basis in the observation group. The Herth hope index (HHI), self - rating anxiety scale (SAS), self - rating depression scale (SDS) and self-feeling burden scale (SPBS) scores of the two groups were compared before and after intervention. Both groups were followed up for 6 months, using the Concise Questionnaire for Psychological Adaptation of Cancer Patients (Min-MAC-19) and the Quality of Life Scale for Brain Tumor Patients (QOL-C30) to assess the improvement of patients' psychological adaptability and quality of life. Results  After intervention, the SAS, SDS, and SPBS scores of the two groups were significantly reduced, and the HHI score was significantly increased. The SAS, SDS, and SPBS scores of the observation group were significantly lower than the control group, and the HHI score was significantly higher than the control group. The differences were statistically significant (P<0.05); After 6 months of follow-up, the observation group Min-MAC-19 and QOL-C30 scores were significantly higher than the control group (P<0.05).  Conclusion Nursing intervention based on Snyder's hope theory can improve the mental state of patients after brain malignancy surgery, reduce the patient's self-experience burden, improve their hope level, psychological adaptability, and improve the quality of life of patients.
A Case Report of Root Resorption after Tooth Dislocation Replantation
Authors: Fang Qian
Published: September 2024

The complete dislocation of the right upper central incisor lasted for more than 2 hours. After 2 weeks of replantation, the ligature was removed. After 1.5 months of reexamination, it was found that the internal and external root absorption of the affected tooth could be slowed down through infection control in the root canal and apical barrier. Reexamination 2.5 months later showed increased bone density around the root of the affected tooth.
Model Construction of Chinese Language Teaching from the Perspective of Artificial Intelligence
Authors: Zang Jinli
Published: September 2024

With the evolution of the information age, artificial intelligence has become an important variable affecting future social development, and its educational value has been widely recognized. In 2018, the Ministry of Education's "Education Informatization 2.0 Action Plan" put forward higher requirements for teaching informatization. The integration of artificial intelligence and education is the only way to improve teaching quality and cultivate talents that adapt to the development of the times. The core of educational informatization is the intelligence of teaching, which makes teaching methods intelligent, educational communication intelligent, and teaching methods technological. In view of this, firstly, the basic characteristics of the teaching information model were analyzed; Secondly, the application of the Chinese language information model was analyzed; Once again, the implementation of the Chinese language information model was analyzed to explore the opportunities and challenges faced by improving the application of artificial intelligence; Finally, from the perspectives of schools and teachers, strategies and suggestions are proposed to improve Chinese language education and teaching from the perspective of artificial intelligence.
The Relationship between Sustainable Development and Organizational Performance of SMEs in Guangdong Province, China
Authors: Li Enhua , Zheng Xiuyun , Pertheban Thillai Raja
Published: September 2024

This study investigates the impact of sustainable development on the organizational performance of small and medium-sized enterprises (SMEs) in Guangdong Province, China, focusing on three dimensions: economic, social, and environmental sustainability. A quantitative research approach was adopted, utilizing Structural Equation Modeling (SEM) with data collected from 371 SMEs in Guangdong Province. The analysis was conducted using SmartPLS 4.0 to test the proposed hypotheses. The results indicate that all three dimensions of sustainable development positively influence organizational performance. Economic sustainability enhances financial performance and competitiveness, social sustainability improves employee engagement and stakeholder relationships, and environmental sustainability reduces operational costs and enhances market reputation. The cross-sectional nature of the study limits the ability to infer causality. Future research should consider longitudinal studies and explore the impact of sustainable development across different regions and industries. SME managers should integrate sustainable practices into their business strategies to improve organizational performance. Policymakers are encouraged to create supportive environments and incentives for SMEs to adopt sustainability practices. This study contributes to the literature by providing empirical evidence on the positive impact of sustainable development on SME performance in the context of a rapidly developing region. It also extends the application of Dynamic Capability Theory to sustainability practices within SMEs.
Present Situation and Challenge of BlM Development in Construction Cost Industry
Authors: Gao Jiawei , Chen Xinhui , Shen Jian
Published: September 2024

This paper analyzes the construction cost situation, BIM technology development, cost measurement methods, cost pricing system, cost control practice and cost management experience of our country and the United Kingdom, the United States and Japan. Finally, the outlook for the future development of engineering cost industry in our country is concluded. and the relevant suggestion is given, which provides a useful reference for the development of engineering cost industry in our country.
Research on the Challenges and Pathways to Improve the Effectiveness of High School English Teaching in the Era of Artificial Intelligence
Authors: Xia Jingling
Published: September 2024

In the era of artificial intelligence, curriculum standards are constantly changing, and higher requirements are placed on students. Due to the constant availability of time, classroom efficiency must be significantly improved. How to improve classroom efficiency and help students achieve higher abilities within a limited time has become a core issue in the education industry. This study aims to explore the challenges in high school English teaching based on the complexity of the English knowledge system, as well as how current artificial intelligence technology can maximize its auxiliary functions. This article mainly analyzes the challenges and path research of improving the effectiveness of high school English teaching under the background of artificial intelligence. It mentions three challenges: low-level motivation of students, low-level work motivation of teachers, and imbalanced use of artificial intelligence, and proposes corresponding solutions, such as using artificial intelligence to provide personalized feedback, using AI-assisted teaching to help teachers enrich teaching forms and reduce burden, and strengthening cross-cultural communication between AI and English, striving to develop more functions of AI that can be used for English teaching.
The Opportunities and Challenges of ChatGPT for Ideological and Political Education of College Students
Authors: Xu Meile
Published: September 2024

In the 21st century, humanity ushered in a wave of artificial intelligence. In the context of big data, generative artificial intelligence has become an important auxiliary tool in the field of education. ChatGPT has gradually entered the learning life of students and reflected its value in ideological and political education in particular. Through a questionnaire survey, this article takes college students as the research object and aims to grasp their evaluations of using ChatGPT and their views on its application in the field of ideological and political education. Research has found that ChatGPT has advantages in optimizing ideological and political evaluation and management systems, helping students understand political theories, enriching teaching models, and meeting the personalized needs of students. The integration of ChatGPT into the class can not only improve teaching quality but also enhance student's learning efficiency and interest. However, the arrival of ChatGPT has also raised a series of ethical risks, such as spreading incorrect information, personal information leakage, academic misconduct, shallow thinking among students, and alienation of teacher-student relationships. In response to these problems brought about by ChatGPT, this article also proposes corresponding risk governance policies. It is necessary to establish a legal supervision mechanism, improve the level of software research and development, enhance the information literacy of teachers and students, and strengthen academic standardization awareness.
Resilience Assessment of Deep Excavation Engineering Systems Based on Bayesian Network
Authors: Liu Ruimin
Published: September 2024

As a key component of infrastructure, the construction safety of deep excavation is particularly important. In order to improve the safety and stability of Deep excavation construction, research on the risk resistance and rapid recovery capabilities of Deep excavation projects is carried out. By introducing the concept of resilience, we analyze the key factors that affect the safety and resilience of Deep excavation projects, use Bayesian networks to establish a resilience model that expresses the causal relationship between factors, and learn the parameters of the network model through data samples collected through surveys; by adjusting the network Analyze the relationship between each factor and system resilience at each node, and clarify the measures that should be taken and key control objects, thereby improving the system resilience and ensuring that normal construction can be carried out safely and orderly. Research shows that this model can be used to quantify the safety toughness value of deep excavation and reason and analyze the impact of various factors on the toughness value, thereby improving risk management and decision support capabilities.
Feasibility of ChatGPT in International Chinese Education
Authors: Sun Lechen
Published: September 2024

With the development and global promotion of Chinese international education, the insufficient distribution of regional resources and the complexity of Chinese learning have gradually emerged. Although the application of ChatGPT to international Chinese education can help solve these problems to a certain extent, there are still some shortcomings. While summarizing the development and characteristics of international Chinese education, this paper analyzes the benefits and negative effects of integrating ChatGPT AI into teaching and learning. Based on the above summary and analysis, this paper discusses the principles that can be adopted by strengthening educational exchanges and cooperation between different regions, actively transforming and improving teachers themselves, strengthening guidance and management of students, helping students cultivate their critical thinking ability, timely adjustment in the process of using ChatGPT according to the actual situation, and emphasizing the combination of theory and practice. Thus, ChatGPT can be better utilized in the teaching and learning activities of international Chinese education.
Research on the Application Status of Generative AI Tools among College Students--Taking ChatGPT as an Example
Authors: Feng Zixin
Published: September 2024

In recent years, artificial intelligence has continuously overcome technological challenges and swept the world at a rapid pace of development. Generative AI tools represented by ChatGPT have undergone extensive language training and made a qualitative leap in capacity algorithms. Although the application status of ChatGPT has received widespread attention, there is still a limited amount of related research and shortcomings. This article takes ChatGPT as an example to analyze the current application status of generative AI tools among college students. Through the collection and organization of survey data, research, and analysis have found that college students have some problems with the actual use of ChatGPT, including insufficient familiarity, inconvenient use of ChatGPT, and lack of autonomy in using ChatGPT among college students. Based on this, this article proposes the following suggestions. Firstly, draw on mature experience and promote digital education. Secondly, offer artificial intelligence courses such as ChatGPT pilot courses. Thirdly, build and improve the digital moral education system and regulatory mechanism.
Design of an Intelligent medication box system
Authors: Wang Bangling , Liu Yong , Rong Xueqin
Published: September 2024

In the context of today's intelligent development, in order to help improve the living experience of the elderly, convenient and intelligent "smart medicine boxes" have begun to enter their lives. The intelligent medication box system designed in this article aims to assist elderly people in taking medication, while monitoring and providing feedback on daily medication usage information. Using microcontroller technology and Bluetooth wireless communication technology, when Bluetooth is in contact with a mobile phone, the indicator light of the smart medicine box will light up, the LCD1602 display screen will prompt medication, and the buzzer will sound an alarm, thereby reminding the elderly to take medication at the appropriate time. When the switch of the smart medicine box fluctuates, the mobile app will provide feedback on the switch status of the medicine box, thereby providing specific information on the medication taking of the elderly. The future application prospects of this system are extremely broad.
Research Progress on Mechanism of Chinese Medicine Intervention on Cuprotosis Induced Apoptosis of Tumor Cells
Authors: Wang Xingsheng , Qin Qishun , Xu Shihong
Published: September 2024

In the current field of cancer treatment, the search for new therapeutic targets and methods remains a focal area of research. Traditional Chinese medicine contains a variety of pharmacologically active components that interact with multiple targets and signaling pathways in the human body, demonstrating potential anti-tumor effects. Copper plays a crucial role in various physiological processes; its homeostasis is tightly regulated to limit the production of oxidative stress and toxicity, and it intervenes in the processes of tumor development, metastasis, and recurrence. Cuproptosis represents a novel form of copper-dependent cell death that differs from previously known regulatory cell death mechanisms, offering a fresh perspective on the link between copper homeostasis and mitochondrial metabolism. Targeting copper has emerged as a new anti-cancer strategy. Current research on the intervention of cuproptosis by TCM is limited; leveraging the advantages of TCM's multi-target, multi-pathway approach could further elucidate the mechanisms of cuproptosis, bringing more possibilities to cancer treatment modalities.