bluuebunny/crossref_metadata_2025 huggingface dataset:
A novel meta learning based stacked approach for diagnosis of thyroid syndrome
Authors: Abbas Muhammad Asad , Munir Kashif , Raza Ali , Amjad Madiha , Samee Nagwan Abdel , Jamjoom Mona M. , Ullah Zahid
Published: November 2024

Thyroid syndrome, a complex endocrine disorder, involves the dysregulation of the thyroid gland, impacting vital physiological functions. Common causes include autoimmune disorders, iodine deficiency, and genetic predispositions. The effects of thyroid syndrome extend beyond the thyroid itself, affecting metabolism, energy levels, and overall well-being. Thyroid syndrome is associated with severe cases of thyroid dysfunction, highlighting the potentially life-threatening consequences of untreated or inadequately managed thyroid disorders. This research aims to propose an advanced meta-learning approach for the timely detection of Thyroid syndrome. We used a standard thyroid-balanced dataset containing 7,000 patient records to apply advanced machine-learning methods. We proposed a novel meta-learning model based on a unique stack of K-Neighbors (KN) and Random Forest (RF) models. Then, a meta-learning Logistic Regression (LR) model is built based on the collective experience of stacked models. For the first time, the novel proposed KRL (KN-RF-LR) method is employed for the effective diagnosis of Thyroid syndrome. Extensive research experiments illustrated that the novel proposed KRL outperformed state-of-the-art approaches, achieving an impressive performance accuracy of 98%. We vindicated the performance scores through k-fold cross-validation and enhanced performance using hyperparameter tuning. Our research revolutionized the timely detection of thyroid syndrome, contributing to the enhancement of human life by reducing thyroid mortality rates.
Rice growth and yield responses to saline water irrigation are related to Na+/K+ ratio in plants
Authors: Paul Priya Lal Chandra , Jahan Afsana , kundu Palash Kumar , Roy Debjit , Bell Richard W. , Hossain Md Belal , Shultana Rakiba , Pranto Mohammad Rezoan Bin Hafiz , Islam Tanjina , Benes Sharon E. , Islam Md Rafiqul
Published: November 2024

Rice growth and yield response to salinity can be influenced by the duration and the timing of salt stress. The present study tested the effects of saline water irrigation from vegetative growth to maturity on rice growth and yield and ion concentrations in the straw and root and related them to changes in soil salinity and soil solute potential. The treatments consisted of five levels of saline water irrigation (electrical conductivity ~0.25 (control), 4, 6, 8, and 10 dS m-1) with two rice cultivars (BRRI dhan67 and BRRI dhan99) grown in pots in a rain shelter. Grain weight per pot, dry straw weight, and root weight were significantly reduced with increasing water salinity, but BRRI dhan99 was less affected. With prolonged saline water irrigation, salt concentration increased in the soil and lowered the soil solute potential. Increased saline water induced higher concentrations of Na+ in the straw (527–1200 mmol kg-1 at 4–10 dS m-1) relative to the root. By contrast, higher Cl- concentrations accumulated in the root than in the straw. The decrease of K+ in the straw and root for increasing salinity was inconsistent, but the Na+/K+ ratio sharply increased in the straw with higher water salinity. The increased Na+/K+ explained most grain weight loss due to higher salinity (R2 = 0.93) followed by Na+ (R2 = 0.87) and Cl-1 (R2 = 0.53). We conclude that the prolonged saline water irrigation has a cumulative effect on root zone salinity and solute potential that depresses grain yield in rice by increasing the Na+/K+ ratio in plants.
Prognostic value of the systemic immune-inflammation index in lung cancer patients receiving immune checkpoint inhibitors: A meta-analysis
Authors: Yang Yanhui , Li Ji , Wang Yi , Luo Lei , Yao Yi , Xie Xiaoyang
Published: November 2024

Purpose

To explore the association between the systemic immune-inflammation index (SII) score and prognosis in immune checkpoint inhibitor (ICI)-treated patients with lung cancer.

Methods

PubMed, EMBASE, Web of Science, and CNKI databases were searched up to August 1, 2024. Progression-free survival (PFS) and overall survival (OS) were the primary outcomes queried. Hazard ratios (HRs) and 95% confidence intervals (CIs) were combined, and subgroup analysis was based on pathological type [non-small cell lung cancer (NSCLC) vs. small-cell lung cancer (SCLC)], lines of ICIs (first-line vs. second- or further-line), and combinations of other therapies (yes vs. no).

Results

Twenty retrospective studies with 2424 participants were included. The pooled results demonstrated that an elevated SII was associated with poorer PFS (HR = 1.82, 95% CI: 1.49–2.21; P < 0.001) and OS (HR = 2.31, 95% CI: 1.73–3.09; P < 0.001) in lung cancer patients receiving ICIs. Subgroup analysis stratified by pathological type, lines of ICIs and combinations of other therapies for PFS and OS further revealed the predictive role of the SII in ICI-treated lung cancer patients.

Conclusion

Based on current evidence the SII is significantly related to prognosis and could serve as a reliable prognostic indicator in lung cancer patients receiving ICIs.
Use of dislodgeable foliar residue studies for the evaluation of isomerization potential of active substances for non-dietary risk assessment
Authors: Wagner Silke , Kuster Christian J.
Published: November 2024

When assessing the non-dietary risks for operators, workers, bystanders and residents to active substances in plant protection products (PPPs) that contain stereoisomers, the EFSA guidance on stereoisomers recommends the application of uncertainty factors when the initial ratio of stereoisomers undergoes a significant stereoisomeric excess change of more than 10%. This precautionary approach may be over-conservative in cases where the change in isomers is due to differences in their degradation rates rather than conversion of one isomer to a potentially more toxic isomer. Therefore, the impact of isomeric composition in non-dietary risk assessments of PPPs was evaluated, with particular emphasis on dislodgeable foliar residues (DFR) data and potential enantioselective degradation processes. Hypothetical outcomes are discussed as well as an evaluation of data for 5 compounds from a total of 35 DFR studies conducted under GLP, aimed at deriving DFR values for higher tier assessments. The findings indicate that possible isomerization of the active substance on leaves can be detected in DFR studies, which is essential for assessing risks to workers and residents. The results of this evaluation highlight the potential for over-conservatism of the current EFSA method for calculating uncertainty factors in non-dietary risk assessments. The EFSA method’s reliance on worst-case assumptions, coupled with the lack of a formal statistical basis, can lead to overestimation of exposure, as illustrated in our theoretical considerations and supported by empirical data from DFR studies. To address this, we propose an alternative approach to evaluating risk considering both degradation and interconversion rates.
Examining HPV vaccination behavior among young adults: Insights from applying the Health Belief Model
Authors: Oyedeji Oluwafemifola , Kintziger Kristina W. , Springer Cary M. , Ehrlich Samantha , Maples Jill , Gatwood Justin , Barroso Cristina S.
Published: November 2024

Background

Despite evidence-based recommendations for HPV vaccination, uptake among young adults is suboptimal. Limited research has explored factors that may influence HPV vaccination among young adults, as well as associated promotion and informational preferences in this group. This study aimed to examine factors associated with HPV vaccination among young adults and preferences for HPV vaccine information and promotion.

Methodology

This study utilized a cross-sectional design to examine factors related to HPV vaccination among young adults on a university campus in Tennessee. Data were collected via an online survey administered to students, aged 18–26 years, from March–May 2023. Study measures included sociodemographic characteristics, health/healthcare-related factors, and perception-related measures. Data analysis included descriptive statistics and multivariable logistic regression analysis.

Results

Out of 402 participants that completed the survey, 209 reported being vaccinated against HPV. In the adjusted model, variables associated with HPV vaccination were perceived risk (adjusted OR [aOR] = 1.12; 95% confidence interval [CI]:1.05, 1.20), perceived barriers (aOR = 0.73; 95% CI: 0.66, 0.81), higher HPV knowledge (aOR = 1.17; 95% CI: 1.03, 1.33), and receipt of healthcare provider recommendations (aOR = 12.90; 95% CI: 7.08, 23.51).

Conclusions

Study findings suggest that those who are vaccinated were more likely to report receiving healthcare provider recommendations, low perceived barriers, higher HPV knowledge and perceived risk. Future HPV vaccination promotion efforts for young adults may consider increasing HPV vaccine knowledge and awareness, addressing barriers, and strengthening provider recommendations.
Unsupervised learning for real-time and continuous gait phase detection
Authors: Anopas Dollaporn , Wongsawat Yodchanan , Arnin Jetsada
Published: November 2024

Individuals with lower limb impairment after a stroke or spinal cord injury require rehabilitation, but traditional methods can be challenging for both patients and therapists. Robotic systems have been developed to help; however, they currently cannot detect the continuous gait phase in real time, hindering their effectiveness. To address this limitation, researchers have attempted to develop gait phase detection in general using fuzzy logic algorithms and neural networks. However, there is a paucity of research on real-time and continuous gait phase detection. In light of this gap, we propose an unsupervised learning method for real-time and continuous gait phase detection. This method employs windows of real-time trajectories and a pre-trained model, utilizing trajectories from treadmill walking data, to detect the real-time and continuous gait phase of human on overground locomotion. The neural network model that we have developed exhibits an average time error of less than 11.51 ms across all walking conditions, indicating its suitability for real-time applications. Specifically, the average time error during overground walking at different speeds is 11.20 ms, which is comparatively lower than the average time error observed during treadmill walking, where it is 12.42 ms. By utilizing this method, we can predict the real-time phase using a pre-trained model from treadmill walking data collected with a full motion capture system, which can be performed in a laboratory setting, thereby eliminating the need for overground walking data, which can be more challenging to obtain due to the complexity of the setting.
Coverage and determinants of Intermittent Preventive Treatment in pregnancy (IPTp) in Cameroon, Guinea, Mali, and Nigeria
Authors: Nishan M. D. Nahid Hassan , Akter Khadiza
Published: November 2024

Introduction

Malaria poses a serious issue for pregnant women in African regions. It is crucial to comprehend the various factors that impact receiving IPTp during ANC checkups. These are important for the well-being of both pregnant mothers and their unborn children. Therefore, this study aims to investigate the determinants of IPTp coverage among women in Cameroon, Guinea, Mali, and Nigeria.

Methodology

This cross-sectional study utilized secondary data from the Malaria Indicator Surveys (MIS) across Cameroon, Guinea, Mali, and Nigeria, focusing on women who received IPTp during pregnancy with IPTp categorized dichotomously as "Yes" for ANC visits and "No" for other visits. Chi-squared tests were used to assess associations, and binary logistic regression was conducted to calculate adjusted odds ratios, confidence intervals, and p-values. Results were summarized in tables.

Results

We found IPTp coverage during ANC visits was highest in Cameroon (98.6%), followed by Guinea (97.7%), Mali (97.1%), and lowest in Nigeria (95.5%). In Guinea, rural women were less likely to receive IPTp than urban women (AOR: 0.16, 95% CI: 0.07–0.41, p<0.001). In Mali, women who received 3 or more doses were less likely to receive IPTp at ANC (AOR: 0.48, p<0.01). In Nigeria, personal transport increased IPTp uptake (AOR: 1.88, p<0.01). In Cameroon, malaria prevention messages improved IPTp coverage (AOR: 3.12, p<0.05).

Conclusions

This study highlights significant disparities in IPTp uptake, with rural Mali and Guinea facing lower coverage. In Nigeria, personal transport improved IPTp uptake. Targeted interventions are needed to improve ANC services and ensure equitable IPTp access across the study regions.
The effectiveness of language nursing intervention on mental health in children with poor language skills
Authors: Shu Xi , Xiao Yingzi , Yang Lingzhi
Published: November 2024

Background

Mental health issues in adulthood often start in childhood, so it’s important to identify these issues early and find ways to manage them. To our knowledge, no study was found that evaluated the long-term effects of language nursing intervention on mental health in children with poor language skills. This study, therefore, aimed to evaluate the long-term impact of a language nursing intervention on the mental health of children with poor language skills.

Methods

We estimated poor language skills prevalence in 3-4-year-old children who were planning to enter kindergartens in Hunan, China. After selecting these children, we divided them into two experimental and control groups. The experimental group received a nursing intervention related to language skills for eight months. After eight months, the language skills of both groups were re-evaluated. Then, in the follow-up evaluation, the mental health of these children was evaluated at the ages of 9–10 years. Univariate and multivariate regression models adjusted with sampling weights were used to estimate the correlation of mental health and risk factors.

Results

The language skills of the experimental group increased significantly compared to before the protocol (from 87.4±10.87 to 98.08±7.13; p = 0.001). At the end of the eight-month nursing intervention, the language skills of the experimental group were significantly higher than the control group (98.08±7.13 in experimental group and 87.51±9.59 in control group; p = 0.001). In multivariate analysis, single-parent family and not participating in the nursing protocol related to language skills at the age of 3–4 years were related to high symptoms of depression, anxiety and stress symptoms (single-parent family: for depression symptoms, OR = 1.28, 95% CI = 0.88–1.42; for stress symptoms, OR = 1.31, 95% CI = 0.79–2.74 and for anxiety symptoms, OR = 1.42, 95% CI = 0.97–2.44; not participating in the nursing protocol related to language skills at the age of 3–4 years: for depression symptoms, OR = 2.98, 95% CI = 1.80–5.19; for stress symptoms, OR = 1.88, 95% CI = 1.23–2.01 and for anxiety symptoms, OR = 2.67, 95% CI = 1.51–3.77; p<0.05).

Conclusion

The current study showed the effectiveness of this intervention on both language skills and mental health of children with poor language skills.
Magnitude and factors associated with iron supplementation among pregnant women in anemia hot spot regions of Ethiopia: Multilevel analysis based on Bayesian approach
Authors: Negesse Yilkal , Temesgen Habtamu , Woyraw Wubetu , Alie Melsew Setegn , Negesse Ayenew
Published: November 2024

Background

According to World Health Organization, pregnant women should take an oral iron and folic acid every day for at least 3 months to prevent preterm birth, low birth weight, maternal anemia, and puerperal sepsis. In addition to keeping maternal health, it also plays a key role to support the fetus’s healthy growth and development. Therefore, it is very important to know the magnitude of iron supplementation and its determinants in anemia hot spot regions of Ethiopia using an appropriate statistical analysis method.

Objective

The aim of this study is to determine the magnitude of iron supplementation and its associated factors in anemia hot spot regions of Ethiopia among pregnant women.

Methods

The study was done using the 2019 Ethiopian Mini Demographic and Health surveys data. Before any statistical analysis was done, the data were weighted using sampling weight for probability sampling and non-response. Then, a total weighted sample of 2116 reproductive age group women in anemia hot spot regions of Ethiopia were used for this study. A multilevel binary logistic regression model based on the Bayesian approach was fitted using the Brms R package to identify the determinants of iron supplementation in anemia hotspot regions of Ethiopia. Finally, the 95% credible interval (CrI) of the adjusted odds ratio (AOR) was used to assess statistical significance. If the interval includes 1, the result is considered non-significant.

Results

This study showed that in anemia hotspot regions of Ethiopia, the overall magnitude of iron supplementation among pregnant women is 55.5% (95% CrI: 53.4%- 57.6%). Being rural resident (AOR = 0.57; 95% CrI 0.34–0.93), having higher education level (AOR = 3.2; 95% CrI 1.80–5.7), having secondary education level (AOR = 3.28; 95% CrI 2.13–5.1), being wealthy (AOR = 1.80; 95% CrI 1.27–2.54), being household headed by female (AOR = 0.55; 95% CrI 0.43–0.71) and, have no children (AOR = 0.4;95%CrI 0.17–0.98) were significantly associated with iron supplementation among pregnant women in anemia hotspot regions of Ethiopia.

Conclusion

The overall magnitude of iron supplementation among pregnant women in anemia hotspot regions of Ethiopia is notably low when compared to the World Health Organization’s recommended target. Significant factors associated with higher iron supplementation included having secondary or higher education, rich in wealth, and being from a male-headed household. Conversely, being a rural resident, female-headed household, and having no children were associated with lower iron supplementation.
The effects of financial spatial structure on household financial vulnerability: Evidence from China
Authors: Gao Hang
Published: November 2024

Based on the panel data of Chinese Family Panel Studies (CFPS) and cities from 2012 to 2020, this paper explores the impact of financial spatial structure on household financial vulnerability and the moderating effect of financial regulation and financial technology from the perspective of the “local market effects” and “spatial spillover effects” of finance. It is indicated that: firstly, the “local market effects” and “spatial spillover effects” of financial spatial structure effectively alleviate household financial vulnerability and the conclusion is still hold true after conducting endogeneity analysis and a series of robustness test. Secondly, promoting household entrepreneurship, optimizing asset allocation, and enhancing residents’ financial literacy are crucial channels through which financial spatial structure influences household financial vulnerability. Thirdly, financial regulation helps to build a fair and transparent financial market, thereby strengthening the positive effects of “local market effects” and “spatial spillover effects” of finance on household financial vulnerability. Financial technology has improved the quality and efficiency of traditional financial services, helping to further leverage the “local market effects” of finance, while it has no obvious impact on strengthening the “spatial spillover effects” of finance. By subdividing the application areas of financial technology, it is observed that the digitalization of payment and insurance businesses can help alleviate household financial vulnerability through the “spatial spillover effects” of finance.
The Human Rights and Social Justice: interconnected Pillars for Equity.
Authors: Enekwe Franklin Sochima
Published: November 2024

Human rights and social justice are fundamental constructs that aim to foster an equitable society. This article explores the intricate relationship between human rights and social justice, emphasizing their role in promoting dignity, equality, and respect for all individuals. By examining the historical context, theoretical frameworks, and current challenges, this study underscores the necessity of integrating human rights into the social justice movement. A comprehensive analysis of relevant literature highlights the need for a multifaceted approach that encompasses legal, social, and economic dimensions. Ultimately, we argue that advancing human rights is critical to achieving social justice, and vice versa, creating a sustainable path toward global equity.
Analysis of Accessibility and Affordability of Hearing Healthcare Services in Iganga District, Uganda
Authors: Tegulwa Miriam
Published: November 2024

Hearing loss is a significant public health concern in Uganda, particularly in rural areas. This study assessed the accessibility and affordability of hearing healthcare services in Iganga District. The study determined the accessibility and affordability of hearing healthcare services, identify barriers to access, and propose recommendations for improvement. The study was conducted at Iganga General Hospital, which is a regional Hospital in the District.

A mixed methods approach was employed. It involved descriptive analytics and qualitative approaches. A total of 49 clients with hearing loss issues were involved in this study and these were recruited from Iganga General Hospital. Data was entered in SPSS software and analyzed.

The study revealed that 83.7% of respondents reported unavailability of hearing healthcare services, which limit accessibility to hearing healthcare services at the Hospital. Results showed that the hospital has no Audiologist to handle hearing issues. The study also showed that hearing healthcare services are not affordable with 79.6% missed appointments due to cost concerns. High costs of treatment (34.7%), transportation (34.7%), and lack of insurance coverage (30.6%) were significant barriers. Only 10.2% found services affordable.

Hearing healthcare services in Iganga District face significant accessibility and affordability challenges. Addressing these disparities requires multifaceted interventions. Therefore, increasing mobile hearing care units, building more healthcare facilities, enhancing community awareness, providing more healthcare professionals, reducing costs, and fostering partnerships with NGOs/Charitable organizations can improve hearing healthcare delivery.
The Philosophical Interpretation of Religion: A Reevaluation of Belief Systems.
Authors: Enekwe Franklin Sochima
Published: November 2024

The philosophical interpretation of religion seeks to unpack the complex interplay between belief systems, ethical frameworks, and cultural narratives. This article explores key philosophical perspectives on religion, highlighting the contributions of major thinkers such as Immanuel Kant, Friedrich. It argues for a critical reevaluation of morality within religious contexts and emphasizes the need for dialogue among diverse belief systems to foster mutual understanding and coexistence.
Lecturing Reference Guide - BIM Teaching Approach
Authors: Nývlt Vladimír , Vytlačil Dalibor , Demel Jiří , Kaiser Jiří , Švamberková Lucie , Prušková Kristýna , Dědič Martin , Veselka Jakub , Šinkner Robert , Jirotková Lucie , Rodrigues Hugo , Rodrigues Fernanda , Alves Ana , Sugiyama Gabriel , Clemen Christian , Schäfer Kathleen , Meyer-Ros Kerstin , Bong Alexander
Published: November 2024

The Lecturers Reference Guide for BIM (Building Information Modeling) is a specialized manual intended for educators in Higher Education Institutions (HEI) who are involved in Architecture, Engineering, and Construction (AEC) courses. The primary goal of this guide is to enhance lecturers’ level of competence in integrating BIM methodology into their teaching in a manner that is both collaborative and integrated. In essence, this guide serves as a comprehensive resource for lecturers, providing them with the tools and knowledge needed to effectively teach BIM in a way that aligns with the collaborative and integrated nature of this modern methodology in the AEC industry.
Referenzhandbuch für Lehrende – BIM - Lehre
Authors: Nývlt Vladimír , Vytlačil Dalibor , Demel Jiří , Kaiser Jiří , Švamberková Lucie , Prušková Kristýna , Dědič Martin , Veselka Jakub , Šinkner Robert , Jirotková Lucie , Rodrigues Hugo , Rodrigues Fernanda , Alves Ana , Sugiyama Gabriel , Clemen Christian , Schäfer Kathleen , Meyer-Ros Kerstin , Bong Alexander
Published: November 2024

Das REFERENZHANDBUCH FÜR LEHRENDE – BIM-LEHRE (BIM = Building Information Modeling) ist ein spezielles Handbuch, das sich an Lehrkräfte an Hochschulen richtet, die Kurse in den Bereichen Architektur, Ingenieurwesen und Bauwesen (engl. Architecture, Engineering and Construction, kurz AEC) anbieten. Das Hauptziel dieses Leitfadens ist es, die Kompetenz der Dozenten bei der Integration der BIM-Methodik in ihren Unterricht auf eine Art und Weise zu verbessern, die sowohl kooperativ als auch integriert ist. Im Wesentlichen dient dieser Leitfaden als umfassende Ressource für Dozenten, um ihnen die Werkzeuge und das Wissen an die Hand zu geben, das sie benötigen, um BIM auf eine Art und Weise zu lehren, die dem kollaborativen und integrierten Charakter dieser modernen Methodik in der AEC-Branche entspricht.
Effigial Lynching and Mediated Circulation in Football Jersey Burning
Authors: Nagel Jeff , Perry Samuel P.
Published: November 2024

Spurred on by comments by then San Francisco 49ers quarterback Colin Kaepernick, the 2017 National Football League (NFL) season became defined through NFL players kneeling during the national anthem to protest ongoing racial inequity and police violence. Mirroring Kaepernick's decision to kneel during the national anthem, players sought to bring awareness to injustice and spark conversation around contemporary social issues. Instead, the contexts of professional sport and the patriotism that surrounds the flag and anthem all activated white supremacist ressentiment and anger. Fans and nonfans alike burned players’ jerseys, posting and circulating these images online in a reactionary media ecology. In this essay, we name this rhetorical act “effigial lynching,” highlighting its shared purposes, forms, and tropes with the historical act of spectacle lynchings in nineteenth-century America. By correctly naming these acts as such, this essay reveals shared linkages between white performances of spectacle violence in the past and present.
Epicuro e Lafargue: por um hedonismo revolucionário
Authors: Silva André
Published: November 2024

Resumo: Este trabalho objetiva analisar a crítica ao capitalismo feita por Paul Lafargue (1842-1911) no opúsculo O direito à preguiça, bem como, as possíveis contribuições da ética de Epicuro a essa crítica. Para Lafargue, o capitalismo industrial é responsável por criar uma moral que coloca o trabalho como virtude e a preguiça e os prazeres como vícios. Para Epicuro (341 a.C. – 270 a.C.) apenas uma vida repleta de prazeres verdadeiros perfaz o homem livre e a vida realmente feliz. No entanto, a moral capitalista, antitética em relação àquela vigente na Grécia antiga, na qual o trabalho afigurava-se como uma atividade de menor valor, afirma o trabalho e em seguida, o consumo, como a finalidade suprema da vida humana. Como consequência dessa supervalorização do trabalho, o proletariado é convencido de que o trabalho é uma necessidade natural, classificada como atividade superior ao gozo ou como condição inalienável para o mesmo. Constatadas as convergências conceituais entre Epicuro e Lafargue, este trabalho apresenta a possibilidade de um hedonismo revolucionário, isto é, uma posição filosófica e política que desconstrói o trabalho como virtude e afirma, como virtuoso, o homem livre e apto para os prazeres verdadeiros, tais como a preguiça e a reflexão filosófica.
Palavras-chave: Capitalismo; Trabalho; Preguiça; Vício; Virtude
Epicurus and Lafargue: for one revolutionary hedonism
Abstract: This work aims to analyze the criticism of capitalism made by Paul Lafargue (1842-1911) in the booklet The right to laziness, as well as the possible contributions of Epicurus' ethics to this criticism. For Lafargue, industrial capitalism is responsible for creating a morality that places work as a virtue and laziness and pleasure as vices. For Epicurus (341 B.C – 270 B.C) only a life full of true pleasures makes up a free man and a truly happy life. However, capitalist morality, antithetical to that prevailing in ancient Greece, in which work appeared as an activity of lesser value, affirms work, and then consumption, as the supreme purpose of human life. As a consequence of this overvaluation of work, the proletariat is convinced that work is a natural need, classified as an activity superior to enjoyment or as an inalienable condition for it. Having verified the conceptual convergences between Epicurus and Lafargue, this work presents the possibility of a revolutionary hedonism, that is, a philosophical and political position that deconstructs work as a virtue and affirms, as virtuous, the free man and apt for true pleasures, such as such as laziness and philosophical reflection.
Keywords: Capitalism; Work; Laziness; Addiction; Virtue
 
Data de registro: 21/07/2023
Data de aceite: 26/09/2024
Baseline magnetic susceptibility measurements of rocks in the Precambrian basement terrain of southwestern Nigeria
Authors: C. Okpoli Cyril , Michael A Oladunjoye , Herrero-Bervera Emilio
Published: November 2024

Petrological, mineralogical and magnetic susceptibility measurements have been studied within the southwestern Nigeria Precambrian basement rocks. Detail geological mapping and core sampling was done for mineralogical characterisation and magnetic susceptibility of the rock samples. Results of the petrographic analyses revealed: quartz, feldspars, hornblende, biotite and opaque (magnetite, ilmenite, maghemite, titanomaghemite) minerals; with minor component of ferromagnesian minerals like hornblende. Quartz, Microcline and Plagioclase alone constitute up to volume fractions 70 % of the rock in the thin section with plagioclase being the most dominant. The magnetic measurements have revealed that the volume susceptibilities K from the investigated samples range from 0.2 to 56,419 X10-6 [SI]. Charrnockites, Granite, biotite granite gneiss, banded gneiss, gneiss, aplite dike, granite, diorite granite gneiss ranges from: 10,059-56,419; 247-12856;0.2-129; 20.4-39.4; 14.1-22,366; 20-8250; 14-30233;4467-6641; and 632-26,921 X 10-6 [SI] respectively. Differential results in the frequency distribution is due varied composition of the paramagnetic (low magnetic susceptibility) and ferromagnetic (high magnetic susceptibility) grains in the rock specimen.
O efeito de uma nova intervenção terapêutica incluindo oxigênio ativo no tratamento da halitose: um ensaio clínico de braço único
Authors: Tavares Rodrigo , Cadore-Rodrigues Ana , Mendonça Thasiane , Pinto João
Published: November 2024

﻿OBJETIVO: Avaliar o efeito do uso combinado de dois produtos contendo oxigênio ativo (enxaguante bucal e creme dental BlueM®) no tratamento da halitose, além de observar o efeito desses produtos na qualidade de vida relacionada à halitose. MÉTODOS: O hálito de 17 indivíduos foi avaliado por meio de avaliação organoléptica e monitor portátil de sulfeto (Halimeter®). Os participantes foram orientados a usar o creme dental por dois minutos durante a escovação dos dentes, três vezes ao dia, e a enxaguar com o enxaguante bucal por 60 segundos, duas vezes ao dia. Após 14 dias, os...
A importância do processo diagnóstico
Authors: Miranda Águida , Rocha André
Published: November 2024

﻿Nós, cirurgiões bucomaxilofaciais, devemos estar atentos, em todas as nossas ações assistenciais, ao processo diagnóstico, que deve ser sólido, baseado em semiologia adequada, exames complementares bem indicados e avaliados de maneira que se construam diagnóstico e prognóstico, e se defina a conduta. Isso é válido tanto nos casos em que tratamos as doenças neoplásicas, as doenças reacionais/inflamatórias do complexo maxilofacial, quanto nos casos de trauma, de deformidades dentofaciais e das enfermidades da ATM.
Importância da fotobiomodulação e magnetoterapia na osteonecrose dos maxilares
Authors: Rodriguez André , da Silva Carlos , Reis Edmilson , Cabral Amanda , Zamuner Stella , Chavantes Maria
Published: November 2024

﻿Introdução: Bisfosfonatos são medicamentos que inibem a reabsorção óssea, cuja prescrição foi, inicialmente, restrita a doenças que interferiam no metabolismo ósseo. Porém, atualmente têm sido prescritos para tratar a osteoporose e até mesmo os casos de osteopenia, causando sérios efeitos adversos, como a osteonecrose dos maxilares — com complicações muito graves e mutilantes —, levando à piora da qualidade de vida desses pacientes. Objetivo: Avaliar os efeitos anti-inflamatórios, antiedematosos, analgésicos e cicatrizantes da fotobiomodulação e magnetoterapia,...
Granuloma piogênico na língua: relato de caso clínico cirúrgico
Authors: Santana Natália , Botelho Maria , Oliveira Denise , Ferreira Danila , Ferreira Pedro
Published: November 2024

﻿Introdução: O granuloma piogênico é uma lesão benigna não-neoplásica e que, apesar de não ter patogênese definida, é classificada como uma lesão reacional a injúrias e estímulos. Objetivo: O objetivo desse estudo é relatar um caso de granuloma piogênico, considerando diagnóstico e tratamento cirúrgico. Caso clínico: Paciente do sexo feminino, 54 anos de idade, relatou o surgimento de uma lesão na língua, com três meses de evolução, apresentando dor e ardência. No exame físico intrabucal, observou-se nódulo na borda lateral posterior da língua do lado esquerdo,...
Bruxismo do sono: novos conceitos
Authors: Crosara Abrahão Cunha Thays , Januzzi Eduardo , Rossi Rowdley , Dal Fabbro Cibele
Published: November 2024

O bruxismo é uma atividade muscular mastigatória (AMM) exacerbada, caracterizada pelo apertamento e/ou ranger dos dentes, pela contração dos músculos da mastigação ou, ainda, pela protrusão mandibular, sem necessariamente ter o toque entre os dentes1. É classificado em bruxismo do sono (BS) e de vigília (BV), pela ritmicidade circadiana. Nesse artigo abordaremos exclusivamente os novos conceitos relacionados ao bruxismo do sono.
Reabilitação estética do sorriso com coroas cerâmicas cimentadas em retentores metálicos opacificados com resina composta: relato de caso
Authors: Fernandes de Araújo Consuelo , Daniela de Andrade Marli , Silveira Tosta Figueiredo Rodrigo , Vinicius Soares Paulo
Published: November 2024

﻿Objetivo: Ilustrar para o cirurgião- dentista uma visão estética, conservadora, sem a real necessidade da remoção dos retentores metálicos, considerando-se o risco de fratura durante a remoção e buscando a harmonia do sorriso por meio da opacificação do substrato. Relato de caso: A paciente relatou ter vergonha de sorrir, por achar os dentes escuros e pequenos. Após realização do exame clínico e radiográfico, constatou- se que os dentes #21 e #22 estavam escurecidos devido a retentores metálicos, e que havia a possibilidade de se remover aproximadamente 3mm de tecido...
Pengaruh Smart Mobility dalam Aplikasi Trans Semarang Terhadap Kepuasan Masyarakat di Kota Semarang
Authors: Ramadhandy Rizki , Harahap Ariq Arsalan , Al Kautsar Muhammad Aslamy , Allaam Naufal Muhammad , Mulyana Nisa Arifah , Gunawana Arien Arianti
Published: November 2024

Penelitian ini membahas dampak penerapan Smart Mobility melalui aplikasi Trans Semarang terhadap kepuasan masyarakat dalam konteks transportasi umum. Fokus utama adalah mengevaluasi bagaimana teknologi transportasi, terwujud dalam aplikasi tersebut, memberikan kontribusi pada kemudahan akses, efisiensi perjalanan, dan tingkat kepuasan pengguna. Metode penelitian yang digunakan menggunakan metode kuantitatif, dengan menyebar kuesioner kepada masyarakat yang berada di Kota Semarang. Hasil penelitian menunjukkan bahwa Trans Semarang berhasil meningkatkan kualitas layanan transportasi umum, menciptakan lingkungan yang lebih efisien, dan menghasilkan tingkat kepuasan masyarakat yang lebih tinggi dalam hal mobilitas perkotaan.
Analysis of Secondary School Infrastructure Distributions in Osogbo Metropolis, Nigeria
Authors: OLAYIWOLA OLAYODE , Sunday Ogundahunsi Dele , Binde Gasu Martins , Babatunde Adedotun Samuel Babatunde , Christiana Olayode
Published: November 2024

This study analysed the geospatial distribution of secondary schools infrastructure in the Osogbo metropolis, Nigeria, with a focus on evaluating accessibility and spatial patterns of school locations. By examining the spatial distribution, travel distances, and clustering of schools, this research offers a novel contribution to the educational planning literature. The data were collected through both primary and secondary sources, utilizing total enumeration for spatial data and a sampling frame of 17,595 students and 452 teachers across 120 public and private secondary schools. Using a balloting approach, at 15%, 19 schools were sampled, followed by a random sampling technique to choose 5% of students and staff, resulting in a total of 906 respondents (880 students and 26 teachers). The analysis, employing Moran's I Index, revealed a value of 0.75 and a p-value of 0.14, indicating a random distribution of schools with a z-score of 1.45, falling within the expected range. The average distance traveled to schools was 1.582 km, reflecting spatial inequities in accessibility. This study provides critical insights for policymakers, emphasizing the need for both public and private stakeholders to ensure equitable distribution and accessibility of secondary schools across Osogbo metropolis.
Arahan Peningkatan Kinerja Saluran Drainase pada Koridor Jalan Barito Kelurahan Simpang Tiga Kota Samarinda
Authors: Setyawan Trisna Adji , Yorika Rahmi
Published: November 2024

Kelurahan Simpang Tiga dalam Dokumen Rencana Tata Ruang Wilayah Kota Samarinda tercatat sebagai kawasan rawan banjir, di mana salah satu instrumen pengendalian banjir yang digunakan adalah pengelolaan sistem drainase terpadu. Penelitian ini bertujuan untuk memberikan arahan peningkatan kinerja saluran drainase dengan tiga langkah sasaran: (1) Menghitung kinerja teknis saluran drainase berdasarkan nilai kemampuan drainase, (2) Menganalisis faktor sosial yang mempengaruhi kinerja drainase, dan (3) Merumuskan program peningkatan kinerja saluran drainase. Berdasarkan analisis teknis, jaringan drainase dinilai melalui waktu konsentrasi, intensitas curah hujan, dan koefisien aliran gabungan untuk menentukan debit limpasan. Semakin tinggi koefisien aliran, semakin besar debit limpasan, yang pada akhirnya akan mempengaruhi kapasitas dan kinerja drainase. Ketika debit limpasan melebihi kapasitas drainase, kondisi drainase dinilai buruk. Hasil penelitian menunjukkan bahwa kinerja teknis drainase di lokasi penelitian bernilai negatif, yang berarti drainase tidak berfungsi dengan baik. Pada kondisi eksisting, banyak endapan lumpur, pasir, dan sampah yang menyumbat aliran, serta dimensi penampang yang tidak seragam menyebabkan genangan. Selain itu, rendahnya kesadaran masyarakat dalam pemeliharaan drainase memperburuk situasi. Berdasarkan kebijakan Pemerintah Daerah dan temuan sebelumnya, disusun program peningkatan kinerja drainase yang meliputi pembangunan ulang dimensi saluran, revitalisasi drainase dengan partisipasi masyarakat, perencanaan saluran drainase dan sanitasi terpadu, serta penetapan regulasi yang mengatur peran serta masyarakat dalam pengelolaan drainase.
Phänomenologie und Offenbarung bei Jean-Luc Marion
Authors: Wohlmuth Josef
Published: November 2024

The article explores the relationship between phenomenon and revelation, primarily on the basis of Being Given: Toward a Phenomenology of Givenness by Jean-Luc Marion. The focus is on Marion’s notion of givenness (inspired by Edmund Husserl), on which he bases his new type of phenomenology of givenness. In a critical discussion with Kant, it is shown that the so-called saturated phenomenon is neither constituted as an object nor can it be related back to an ego. The saturated phenomena show themselves of their own motion, they give themselves in their own non-reducibility. They can only be witnessed by the ego. Four types of such saturated phenomena are presented: event, idol, corporeity and icon. The highest degree of phenomenality is achieved in the phenomenon of revelation. Marion presents Jesus Christ as an example of a possible revelation. The manifestation of Jesus Christ stands for a phenomenon of revelation that unites all forms of saturation in itself, namely in the mode of paradox. The revelation in Jesus Christ is thus presented as a paradigm of a phenomenological revelation.
«Quale Europa cristiana e quale Lutero?» A proposito di un recente volume di F. Buzzi
Authors: Žák Ľubomír J. , de Mico Nico
Published: November 2024

The article aims to draw attention to the book Quale Europa cristiana? La continuità di una presenza (Which Christian Europe? The Continuity of a Presence) by Franco Buzzi, a Milanese theologian and renowned scholar of the Lutheran Reformation. It particularly focuses on Buzzi’s intention to explore the relationship between Western Europe and Christianity, not only regarding the developments stemming from the birth and spread of Luther’s Reformation but also concerning the critique of Luther’s thought and reformist work, which continues to characterise certain strands of Catholic historiography and theology. At the core of this critique lies a twofold conviction: that Luther is the instigator of the division of Christianity and Europe, and that he is the primary cause of the decline of European Christendom. The article explains why Buzzi considers these convictions to be entirely unfounded and unjust. Moreover, it demonstrates that his interpretative stance offers important insights, enabling further progress in exploring the theme of ‘Europe and Christianity’ and examining the interconnection between the unity of Europe and the unity of Christianity.
Formation mechanisms of Qiaoba-Zhongdu Danxia landforms in southwestern Sichuan Province, China
Authors: Wang Qizhong , Zhang Ying , Cheng Zhiheng , Dong ShuYi , Li Zhongquan , Liu Henglin , Li Gen
Published: November 2024

Embarking on systematics, the formation mechanisms of Danxia landforms were explained from perspectives of human activities, geography, and climate. The formation mechanisms of Qiaoba-Zhongdu Danxia landforms in the research region were systematically discussed using theories and methods in sedimentology, paleo-climatology, tectono-dynamics, and surface process dynamics. Meanwhile, approaches such as remote-sensing imagery interpretation, rock and ore identification, geochemical analysis, and interpretation of seismic profiles were also adopted. Research results show that Qiaoba-Zhongdu Danxia landforms are in the mature stage of landform evolution. The formation process involves five stages including being bred by sedimentation, rendered by paleo-environmental conditions, landscaped by tectonism, carved by geomorphologic agents, and embellished by human activities.
Anti-inflammatory activity of Ziziphus jujuba hydroalcoholic extract in acetic acid-induced ulcerative colitis model
Authors: Bahrami Shabnam , Babaei Nahid , Esmaeili Gouvarchin Ghaleh Hadi , Mohajeri Borazjani Jaleh , Farzanehpour Mahdieh
Published: November 2024

Objectives

Ulcerative colitis (UC) is a common gastrointestinal (GI) disorder characterized by chronic inflammation. Current treatments primarily focus on symptom management, but they have inherent limitations. Global attention is increasingly directed towards exploring herbal remedies as complementary approaches. This study aims to investigate the effects of the hydroalcoholic extract of jujuba on an experimental model of ulcerative colitis.

Methods

In this study, 15 male BALB/c mice were divided into three experimental groups. The first group served as the untreated UC model, acting as the positive control (PC). The second group received treatment with the hydroalcoholic extract of Ziziphus jujuba, while the third group was treated with mesalamine. UC was induced by injecting 100 μL of 4 % acetic acid (AA) intra-rectally several times. Treatment commenced after the onset of symptoms such as diarrhea and bloody stools. The mice were eventually euthanized ethically, and their spleen and intestinal tissues were collected for analysis. Evaluations included the Disease Activity Index (DAI), myeloperoxidase activity (MPO), nitric oxide (NO) levels, cytokine levels (IL-1β, IL-6, TNF-α), and gene expression (iNOS, COX-2, and cytokines).

Results

The hydroalcoholic extract of the jujuba plant significantly reduced MPO, NO, the DAI, and the production and expression of inflammatory cytokines, as well as the genes iNOS and COX-2, in the group receiving this extract compared to the positive control group (p<0.05).

Conclusions

The study demonstrates that the hydroalcoholic extract of Ziziphus jujuba significantly reduces inflammation markers such as TNF-α, NO, MPO, IL-1β, and IL-6 in a mouse model of ulcerative colitis. Additionally, it downregulates the expression of pro-inflammatory genes, including iNOS and COX-2. These findings suggest that Z. jujuba extract has potential as an effective anti-inflammatory treatment for managing ulcerative colitis symptoms.
Optimal complexity of goal-oriented adaptive FEM for nonsymmetric linear elliptic PDEs
Authors: Bringmann Philipp , Brunner Maximilian , Praetorius Dirk , Streitberger Julian
Published: November 2024

We analyze a goal-oriented adaptive algorithm that aims to efficiently compute the quantity of interest G(u
⋆) with a linear goal functional G and the solution u
⋆ to a general second-order nonsymmetric linear elliptic partial differential equation. The current state of the analysis of iterative algebraic solvers for nonsymmetric systems lacks the contraction property in the norms that are prescribed by the functional analytic setting. This seemingly prevents their application in the optimality analysis of goal-oriented adaptivity. As a remedy, this paper proposes a goal-oriented adaptive iteratively symmetrized finite element method (GOAISFEM). It employs a nested loop with a contractive symmetrization procedure, e.g., the Zarantonello iteration, and a contractive algebraic solver, e.g., an optimal multigrid solver. The various iterative procedures require well-designed stopping criteria such that the adaptive algorithm can effectively steer the local mesh refinement and the computation of the inexact discrete approximations. The main results consist of full linear convergence of the proposed adaptive algorithm and the proof of optimal convergence rates with respect to both degrees of freedom and total computational cost (i.e., optimal complexity). Numerical experiments confirm the theoretical results and investigate the selection of the parameters.
Stability and error analysis of a semi-implicit scheme for incompressible flows with variable density and viscosity
Authors: Vu An , Cappanera Loic
Published: November 2024

We study the stability and convergence properties of a semi-implicit time stepping scheme for the incompressible Navier–Stokes equations with variable density and viscosity. The density is assumed to be approximated in a way that conserves the minimum-maximum principle. The scheme uses a fractional time-stepping method and the momentum, which is equal to the product of the density and velocity, as a primary unknown. The semi-implicit algorithm for the coupled momentum-pressure is shown to be conditionally stable and the velocity is shown to converge in L
2 norm with order one in time. Numerical illustrations confirm that the algorithm is stable and convergent under classic CFL condition even for sharp density profiles.