bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1 - 3 from Chemotherapeutic Sensitivity of Testicular Germ Cell Tumors Under Hypoxic Conditions Is Negatively Regulated by SENP1-Controlled Sumoylation of OCT4
Authors: Wu Yu-Chih , Ling Thai-Yen , Lu Shing-Hwa , Kuo Hung-Chih , Ho Hong-Nerng , Yeh Shauh-Der , Shen Chia-Ning , Huang Yen-Hua
Published: March 2023

Supplementary Table S1. Primer sequences. Supplementary Table S2. Antibody list. Supplementary Table S3. Mean values of the half maximal inhibitory concentration (IC50; {plus minus} standard deviation; SD) of NCCIT cells under normoxic or hypoxic conditions for 24 h.
Supplementary Figure 1 from Temporary Disruption of the Blood–Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques
Authors: McDannold Nathan , Arvanitis Costas D. , Vykhodtseva Natalia , Livingstone Margaret S.
Published: March 2023

PDF file - 107K, Figure S1: (A) Experimental setup. (B) Beam steering pattern used during volumetric sonication. The order of the nine "subsonications" is indicated. (C) Pulsing scheme used during volumetric sonication. Three 50 s sonications were delivered with a 25 s pause between sonications. During each sonication, 10 ms bursts were delivered to the nine locations in sequence, typically every 200 ms
Supplementary Figure 1 from Mammographic Breast Density and Breast Cancer: Evidence of a Shared Genetic Basis
Authors: Varghese Jajini S. , Thompson Deborah J. , Michailidou Kyriaki , Lindström Sara , Turnbull Clare , Brown Judith , Leyland Jean , Warren Ruth M.L. , Luben Robert N. , Loos Ruth J. , Wareham Nicholas J. , Rommens Johanna , Paterson Andrew D. , Martin Lisa J. , Vachon Celine M. , Scott Christopher G. , Atkinson Elizabeth J. , Couch Fergus J. , Apicella Carmel , Southey Melissa C. , Stone Jennifer , Li Jingmei , Eriksson Louise , Czene Kamila , Boyd Norman F. , Hall Per , Hopper John L. , Tamimi Rulla M. , Rahman Nazneen , Easton Douglas F.
Published: March 2023

PDF file - 275K, Significance of the mammographic breast density polygenic risk score (PRS) for the prediction of breast cancer risk, according to percent cut-off of SNPs used in the PRS: sensitivity analysis using imputed case:control genotype dosages.
Supplementary Table 2 from Genetic Variants in miRNAs Predict Bladder Cancer Risk and Recurrence
Authors: Wang Meilin , Chu Haiyan , Li Pu , Yuan Lin , Fu Guangbo , Ma Lan , Shi Danni , Zhong Dongyan , Tong Na , Qin Chao , Yin Changjun , Zhang Zhengdong
Published: March 2023

PDF file, 22K, Stratified analysis of the association between miR-146a rs2910164 and risk of bladder cancer.
Supplementary Figures 1-3 from CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth
Authors: Claus Christina , Riether Carsten , Schürch Christian , Matter Matthias S. , Hilmenyuk Tamara , Ochsenbein Adrian F.
Published: March 2023

PDF file - 488K, Supplementary Figure 1. Growth of large tumor fragments, anti-tumoral CTL responses and tumor RNA immune gene profile in BL/6 and CD27-/- mice. Supplementary Figure 2. Intratumoral T cell subsets, endogenous CD25+ Tregs and effector T cell apoptosis. Supplementary Figure 3. CD27-/- and BL/6 Tregs equally inhibit the proliferation of CD8+ T cells
Supplementary Figure 3 from Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth
Authors: Prudent Renaud , Vassal-Stermann Emilie , Nguyen Chi-Hung , Pillet Catherine , Martinez Anne , Prunier Chloé , Barette Caroline , Soleilhac Emmanuelle , Filhol Odile , Beghin Anne , Valdameri Glaucio , Honoré Stéphane , Aci-Sèche Samia , Grierson David , Antonipillai Juliana , Li Rong , Di Pietro Attilio , Dumontet Charles , Braguer Diane , Florent Jean-Claude , Knapp Stefan , Bernard Ora , Lafanechère Laurence
Published: March 2023

PDF file - 173K, Characterization of Pyr1 (Pyr1) effects on the inhibition of LIMKs activity in vitro
Supplementary Table 5 from A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer
Authors: Li Ning , Kaur Sippy , Greshock Joel , Lassus Heini , Zhong Xiaomin , Wang Yanling , Leminen Arto , Shao Zhongjun , Hu Xiaowen , Liang Shun , Katsaros Dionyssios , Huang Qihong , Bützow Ralf , Weber Barbara L. , Coukos George , Zhang Lin
Published: March 2023

PDF file - 81K
Supplementary Figure 1 from Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response
Authors: Chang Hsin-Yi , Huang Hsuan-Cheng , Huang Tsui-Chin , Yang Pan-Chyr , Wang Yi-Ching , Juan Hsueh-Fen
Published: March 2023

PDF file, 110K, Distribution of respiratory chain complexes in A549 and CL1-0 cells.
Supplementary Figure 4 from Bioactivity and Prognostic Significance of Growth Differentiation Factor GDF15 Secreted by Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma
Authors: Corre Jill , Labat Elodie , Espagnolle Nicolas , Hébraud Benjamin , Avet-Loiseau Hervé , Roussel Murielle , Huynh Anne , Gadelorge Mélanie , Cordelier Pierre , Klein Bernard , Moreau Philippe , Facon Thierry , Fournié Jean-Jacques , Attal Michel , Bourin Philippe
Published: March 2023

PDF file - 90K, Effect of GDF15 on ERK1/2 phosphorylation in MOLP-6 and MM1.S cells
Supplementary Figure 6 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 622K, Effects of RKIP expression on cell growth
Supplementary Figure 1 from Metastasis Suppressor NM23-H1 Promotes Repair of UV-Induced DNA Damage and Suppresses UV-Induced Melanomagenesis
Authors: Jarrett Stuart G. , Novak Marian , Dabernat Sandrine , Daniel Jean-Yves , Mellon Isabel , Zhang Qingbei , Harris Nathan , Ciesielski Michael J. , Fenstermaker Robert A. , Kovacic Diane , Slominski Andrzej , Kaetzel David M.
Published: March 2023

PDF file - 179K
Supplementary Legends for Figures 1-2 and Table 1 from Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity
Authors: Little Suzanne E. , Popov Sergey , Jury Alexa , Bax Dorine A. , Doey Lawrence , Al-Sarraj Safa , Jurgensmeier Juliane M. , Jones Chris
Published: March 2023

Supplementary Legends for Figures 1-2 and Table 1 from Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity
Supplementary Figure 3 from CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
Authors: De Falco Valentina , Tamburrino Anna , Ventre Simona , Castellone Maria Domenica , Malek Mouhannad , Manié Serge N. , Santoro Massimo
Published: March 2023

PDF file- 142K, The RET-PTC-RAS-BRAF cascade triggers CD44 cleavage
Supplementary Materials and Methods from Regulation of Monocarboxylate Transporter MCT1 Expression by p53 Mediates Inward and Outward Lactate Fluxes in Tumors
Authors: Boidot Romain , Végran Frédérique , Meulle Aline , Le Breton Aude , Dessy Chantal , Sonveaux Pierre , Lizard-Nacol Sarab , Feron Olivier
Published: March 2023

PDF file - 36K
Supplementary Figure 1 from Regulation of Monocarboxylate Transporter MCT1 Expression by p53 Mediates Inward and Outward Lactate Fluxes in Tumors
Authors: Boidot Romain , Végran Frédérique , Meulle Aline , Le Breton Aude , Dessy Chantal , Sonveaux Pierre , Lizard-Nacol Sarab , Feron Olivier
Published: March 2023

PDF file - 27K
Supplementary Figure 2 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: March 2023

PDF file - 824K, Example of the variable number of CD73+ and CD34+ cells detected in different DTs. CD73+ and CD34+ cells were counted at 4 representative high-powered fields (40X) using Image J software. The average number of positive cells per field is shown on the Y axis. DTs from FAP patients vs. sporadic DTs contained variable numbers of MSCs and CD34+ fibrocytes, but these differences were not statistically significant.
Supplementary Figure 2 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: March 2023

PDF file - 255K, Immunohistochemical staining for CA125, WT1 and calretinin
Supplementary Figure 1 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: March 2023

PDF file - 307K, lntrabursal injection of Adeno-Cre activates conditional alleles in OSE cells and induces histopathological changes of murine OSE post induction
Supplementary Figure 8 from NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells
Authors: Yap Kai Lee , Fraley Stephanie I. , Thiaville Michelle M. , Jinawath Natini , Nakayama Kentaro , Wang Jianlong , Wang Tian-Li , Wirtz Denis , Shih Ie-Ming
Published: March 2023

PDF file - 68K, Domain mapping of NAC1 binding region
Supplementary Figure 7 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 150K, Elimination of E-Syt1 expression by RNAi does not abolish CD74-ROS signaling activity
Supplementary Figure 6 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 54K, Assessment of the expression of CCL22 in OC tumors
Supplementary Figure 1 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 181K, The different ROS fusion kinases are oncogenic in fibroblasts
Supplementary Figure Legends 1-9 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDF file - 86K
Supplementary Table 4 from Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity during Carcinogen-Induced Lung Tumorigenesis
Authors: Ihara Shoichi , Kida Hiroshi , Arase Hisashi , Tripathi Lokesh P. , Chen Yi-An , Kimura Tetsuya , Yoshida Mitsuhiro , Kashiwa Yozo , Hirata Haruhiko , Fukamizu Reiko , Inoue Ruriko , Hasegawa Kana , Goya Sho , Takahashi Ryo , Minami Toshiyuki , Tsujino Kazuyuki , Suzuki Mayumi , Kohmo Satoshi , Inoue Koji , Nagatomo Izumi , Takeda Yoshito , Kijima Takashi , Mizuguchi Kenji , Tachibana Isao , Kumanogoh Atsushi
Published: March 2023

PDF file - 76K, Enriched KEGG pathway association (p
Supplementary Figure 7 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 824K
Supplementary Table 2 from Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity during Carcinogen-Induced Lung Tumorigenesis
Authors: Ihara Shoichi , Kida Hiroshi , Arase Hisashi , Tripathi Lokesh P. , Chen Yi-An , Kimura Tetsuya , Yoshida Mitsuhiro , Kashiwa Yozo , Hirata Haruhiko , Fukamizu Reiko , Inoue Ruriko , Hasegawa Kana , Goya Sho , Takahashi Ryo , Minami Toshiyuki , Tsujino Kazuyuki , Suzuki Mayumi , Kohmo Satoshi , Inoue Koji , Nagatomo Izumi , Takeda Yoshito , Kijima Takashi , Mizuguchi Kenji , Tachibana Isao , Kumanogoh Atsushi
Published: March 2023

PDF file - 126K, Genes down-regulated (<0.5) in Stat3delta/delta compared with Stat3flox/flox
Supplementary Figure 2 from Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity during Carcinogen-Induced Lung Tumorigenesis
Authors: Ihara Shoichi , Kida Hiroshi , Arase Hisashi , Tripathi Lokesh P. , Chen Yi-An , Kimura Tetsuya , Yoshida Mitsuhiro , Kashiwa Yozo , Hirata Haruhiko , Fukamizu Reiko , Inoue Ruriko , Hasegawa Kana , Goya Sho , Takahashi Ryo , Minami Toshiyuki , Tsujino Kazuyuki , Suzuki Mayumi , Kohmo Satoshi , Inoue Koji , Nagatomo Izumi , Takeda Yoshito , Kijima Takashi , Mizuguchi Kenji , Tachibana Isao , Kumanogoh Atsushi
Published: March 2023

PDF file - 72K, The expression and activation of Stat3 was intact in both myeloid and lymphocyte lineages in Stat3delta/delta mice
Supplementary Figure 2 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 614K
Supplementary Figure 2 from Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis
Authors: Park Serk In , Liao Jinhui , Berry Janice E. , Li Xin , Koh Amy J. , Michalski Megan E. , Eber Matthew R. , Soki Fabiana N. , Sadler David , Sud Sudha , Tisdelle Sandra , Daignault Stephanie D. , Nemeth Jeffrey A. , Snyder Linda A. , Wronski Thomas J. , Pienta Kenneth J. , McCauley Laurie K.
Published: March 2023

PDF file - 115K, Cyclophosphamide treatment reduced body weight but did not cause systemic inflammation
Supplementary Figure 5 from Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
Authors: Liu Wei , Glunde Kristine , Bhujwalla Zaver M. , Raman Venu , Sharma Anit , Phang James M.
Published: March 2023

PDF file - 282K, Upregulation of POX does not induce apoptosis under hypoxia
Supplementary Figure 2 from Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
Authors: Liu Wei , Glunde Kristine , Bhujwalla Zaver M. , Raman Venu , Sharma Anit , Phang James M.
Published: March 2023

PDF file - 48K, POX mRNA increases in MDA-MB-231 HRE-EGFP breast cancer cells exposed to hypoxia
Supplementary Figure 2 from Mcl-1 Phosphorylation Defines ABT-737 Resistance That Can Be Overcome by Increased NOXA Expression in Leukemic B cells
Authors: Mazumder Suparna , Choudhary Gaurav S. , Al-harbi Sayer , Almasan Alexandru
Published: March 2023

PDF file - 171K, NOXA-mediated Mcl-1 release from the Bim/Mcl-1 complex is critical for gossypol-induced cell death.
Supplementary Figure 3 from Sorafenib Has Potent Antitumor Activity against Multiple Myeloma In Vitro, Ex Vivo, and In Vivo in the 5T33MM Mouse Model
Authors: Kharaziha Pedram , De Raeve Hendrik , Fristedt Charlotte , Li Qiao , Gruber Astrid , Johnsson Per , Kokaraki Georgia , Panzar Maria , Laane Edward , Österborg Anders , Zhivotovsky Boris , Jernberg-Wiklund Helena , Grandér Dan , Celsing Fredrik , Björkholm Magnus , Vanderkerken Karin , Panaretakis Theocharis
Published: March 2023

PDF file - 36K, A, Quantitative analysis of Annexin V/PI positive murine 5T33MMvitro cells treated the indicated concentrations of sorafenib for 24h and 48h; B, Immunoblot analysis of the indicated proteins from the 5T33MMvitro cell line treated with 10 muM Sor for the indicated time points. C, Immunoblot analysis of the indicated proteins from murine 5T33MMvivo treated ex-vivo with 10 muM Sor for 24h
Supplementary Figure 1 from Sorafenib Has Potent Antitumor Activity against Multiple Myeloma In Vitro, Ex Vivo, and In Vivo in the 5T33MM Mouse Model
Authors: Kharaziha Pedram , De Raeve Hendrik , Fristedt Charlotte , Li Qiao , Gruber Astrid , Johnsson Per , Kokaraki Georgia , Panzar Maria , Laane Edward , Österborg Anders , Zhivotovsky Boris , Jernberg-Wiklund Helena , Grandér Dan , Celsing Fredrik , Björkholm Magnus , Vanderkerken Karin , Panaretakis Theocharis
Published: March 2023

PDF file - 26K, The indicated myeloma cell lines were treated with 10 muM Sor for 24h and cell cycle distribution was analysed by NucleoCounter NC-3000 (Chemometec).
Supplementary Figure 4 from Fra-1 Promotes Breast Cancer Chemosensitivity by Driving Cancer Stem Cells from Dormancy
Authors: Lu Dan , Chen Si , Tan Xiaoyue , Li Na , Liu Chenghu , Li Zongjin , Liu Ze , Stupack Dwayne G. , Reisfeld Ralph A. , Xiang Rong
Published: March 2023

PDF file - 4.2MB, Final tumor burden was depicted as size(A) and weight(B) on Day 23 after harvest, and the expression of Fra-1 in these tumors was further confirmed by western-blot(C)
Supplementary Figure 1 from Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
Authors: Friedlander Terence W. , Roy Ritu , Tomlins Scott A. , Ngo Vy T. , Kobayashi Yasuko , Azameera Aruna , Rubin Mark A. , Pienta Kenneth J. , Chinnaiyan Arul , Ittmann Michael M. , Ryan Charles J. , Paris Pamela L.
Published: March 2023

PDF file - 7.7K, Hierarchical Clustering of CRPC Samples by Copy Number and Expression: Clustering of samples by: (A) whole genome copy number (x axis = aCGH probes sorted by chromosome, chromosome 1 on left, chromosome 23 on right, green=gain, red=loss). (B) expression level of frequently copy aberrant genes (x axis=gene expression probes red=overexpressed, blue=underexpressed.
Supplementary Table 2 from Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma
Authors: Wondergem Bill , Zhang Zhongfa , Huang Dachuan , Ong Choon Kiat , Koeman Julie , Hof David Van't , Petillo David , Ooi Aikseng , Anema John , Lane Brian , Kahnoski Richard J. , Furge Kyle A. , Teh Bin Tean
Published: March 2023

XLS file, 27K, Deregulated genes known to promote carcinogenesis, tumor progression, or metastatic dissemination.
Supplementary Figure 2 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
Authors: Bai Yun , Li Jiannong , Fang Bin , Edwards Arthur , Zhang Guolin , Bui Marilyn , Eschrich Steven , Altiok Soner , Koomen John , Haura Eric B.
Published: March 2023

PDF file - 107K, Knockdown efficacy of siRNA
Supplementary Methods from Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Authors: Sceneay Jaclyn , Chow Melvyn T. , Chen Anna , Halse Heloise M. , Wong Christina S.F. , Andrews Daniel M. , Sloan Erica K. , Parker Belinda S. , Bowtell David D. , Smyth Mark J. , Möller Andreas
Published: March 2023

PDF file - 90K
Supplementary Figure Legends 1-4 from Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Authors: Sceneay Jaclyn , Chow Melvyn T. , Chen Anna , Halse Heloise M. , Wong Christina S.F. , Andrews Daniel M. , Sloan Erica K. , Parker Belinda S. , Bowtell David D. , Smyth Mark J. , Möller Andreas
Published: March 2023

PDF file - 72K
Supplementary Figure 1 from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa
Authors: Ng Yi-Zhen , Pourreyron Celine , Salas-Alanis Julio C. , Dayal Jasbani H.S. , Cepeda-Valdes Rodrigo , Yan Wenfei , Wright Sheila , Chen Mei , Fine Jo-David , Hogg Fiona J. , McGrath John A. , Murrell Dedee F. , Leigh Irene M. , Lane E. Birgit , South Andrew P.
Published: March 2023

PDF file - 56K, Unsupervised clustering of the core serum response gene set is able to cluster NHF but not RDEBSCCF sample groups in culture
Supplementary Figure Legends 1-6 from BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy
Authors: Koya Richard C. , Mok Stephen , Otte Nicholas , Blacketor Kevin J. , Comin-Anduix Begonya , Tumeh Paul C. , Minasyan Aspram , Graham Nicholas A. , Graeber Thomas G. , Chodon Thinle , Ribas Antoni
Published: March 2023

PDF file - 66K
Supplementary Figure 1 from BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy
Authors: Koya Richard C. , Mok Stephen , Otte Nicholas , Blacketor Kevin J. , Comin-Anduix Begonya , Tumeh Paul C. , Minasyan Aspram , Graham Nicholas A. , Graeber Thomas G. , Chodon Thinle , Ribas Antoni
Published: March 2023

PDF file - 117K, Analysis of melanoma-like genome-wide DNA copy number alterations in the SM1 cell line
Supplementary Figure Legend from Collaboration of Kras and Androgen Receptor Signaling Stimulates EZH2 Expression and Tumor-Propagating Cells in Prostate Cancer
Authors: Cai Houjian , Memarzadeh Sanaz , Stoyanova Tanya , Beharry Zanna , Kraft Andrew S. , Witte Owen N.
Published: March 2023

PDF file, 28K.
Supplementary Figure 3 from Collaboration of Kras and Androgen Receptor Signaling Stimulates EZH2 Expression and Tumor-Propagating Cells in Prostate Cancer
Authors: Cai Houjian , Memarzadeh Sanaz , Stoyanova Tanya , Beharry Zanna , Kraft Andrew S. , Witte Owen N.
Published: March 2023

PDF file, 83K, IHC staining of Kras(G12D) and AR tumor tissues.
Supplementary Methods and Materials, Figures 1-9 from GLI1 Inhibition Promotes Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells
Authors: Joost Simon , Almada Luciana L. , Rohnalter Verena , Holz Philipp S. , Vrabel Anne M. , Fernandez-Barrena Maite G. , McWilliams Robert R. , Krause Michael , Fernandez-Zapico Martin E. , Lauth Matthias
Published: March 2023

PDf file - 405K
Supplementary Figure 2 from Targeting eNOS in Pancreatic Cancer
Authors: Lampson Benjamin L. , Kendall S. DiSean , Ancrile Brooke B. , Morrison Meghan M. , Shealy Michael J. , Barrientos Katharine S. , Crowe Matthew S. , Kashatus David F. , White Rebekah R. , Gurley Susan B. , Cardona Diana M. , Counter Christopher M.
Published: March 2023

PDF file - 243K, Tumorigenic growth of human pancreatic cancer cell lines treated with L-NAME
Supplementary Figure 1 and Tables 1 - 3 from Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model
Authors: Floc'h Nicolas , Kinkade Carolyn Waugh , Kobayashi Takashi , Aytes Alvaro , Lefebvre Celine , Mitrofanova Antonina , Cardiff Robert D. , Califano Andrea , Shen Michael M. , Abate-Shen Cory
Published: March 2023

PDF file, 4581K, Supplementary Figure 1 and Table 1-3 Supp. Figure 1: Preclinical analyses of intact Nkx3.1CE2/+; Ptenf/f mice Supp. Table 1: List of primers used in this study Supp. Table 2: List of antibodies used in this study Supp. Table 3: Summary of Tumor weights and proliferation of prostate tumor from intact Nkx3.1CE2/+;Ptenf/f mice.
Supplementary Figure Legends 1-9 from VEGF Exerts an Angiogenesis-Independent Function in Cancer Cells to Promote Their Malignant Progression
Authors: Cao Ying , E Guangqi , Wang Enfeng , Pal Krishnendu , Dutta Shamit K. , Bar-Sagi Dafna , Mukhopadhyay Debabrata
Published: March 2023

PDF file - 68K
Supplementary Table 1 from ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features
Authors: Albino Domenico , Longoni Nicole , Curti Laura , Mello-Grand Maurizia , Pinton Sandra , Civenni Gianluca , Thalmann George , D'Ambrosio Gioacchino , Sarti Manuela , Sessa Fausto , Chiorino Giovanna , Catapano Carlo V. , Carbone Giuseppina M.
Published: March 2023

PDF file - 107K, Primer sets for RT-PCR, qRT-PCR and CHIP
Supplementary Figure 3 from Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF-α–Independent Apoptosis
Authors: Eschenburg Georg , Eggert Angelika , Schramm Alexander , Lode Holger N. , Hundsdoerfer Patrick
Published: March 2023

PDF file - 1.9MB, Effects of LBW242 or XIAP silencing on apoptosis induction and caspase activation in SK-N-SH neuroblastoma cells.
Supplementary Tables 2-8 from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: March 2023

PDF file - 41K, Table S2: EGFR gene copy number in neurospheres and the corresponding original glioblastomas. Table S3: Immunophenotype of neurospheres. Table S4: EGFR gene amplification, Met expression, and MET gene alterations in glioblastomas and corresponding neurospheres. Table S5: Multiple transcriptional signatures in Met-neg and Met-pos neurospheres. Table S6: Immunohistochemistry on tumors derived from neurospheres. Table S8: Antibodies used in flow-cytometric analysis
Supplementary Table 7 from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: March 2023

XLS file - 44K, List of primer pairs used for gene sequencing
Supplementary Methods, Table 1, Figure Legends 1-4 from SMYD3 Promotes Cancer Invasion by Epigenetic Upregulation of the Metalloproteinase MMP-9
Authors: Cock-Rada Alicia M. , Medjkane Souhila , Janski Natacha , Yousfi Nadhir , Perichon Martine , Chaussepied Marie , Chluba Johanna , Langsley Gordon , Weitzman Jonathan B.
Published: March 2023

PDF file - 118K
Supplementary Figures 1-6 from Tumor Angiogenesis Mediated by Myeloid Cells Is Negatively Regulated by CEACAM1
Authors: Lu Rongze , Kujawski Maciej , Pan Hao , Shively John E.
Published: March 2023

PDF file - 4MB
Supplementary Methods from CDK8 Maintains Tumor Dedifferentiation and Embryonic Stem Cell Pluripotency
Authors: Adler Adam S. , McCleland Mark L. , Truong Tom , Lau Shari , Modrusan Zora , Soukup Tim M. , Roose-Girma Merone , Blackwood Elizabeth M. , Firestein Ron
Published: March 2023

PDF file - 36K
Supplementary Figure Legends from Vitronectin–αvβ3 Integrin Engagement Directs Hypoxia-Resistant mTOR Activity and Sustained Protein Synthesis Linked to Invasion by Breast Cancer Cells
Authors: Pola Carolina , Formenti Silvia C. , Schneider Robert J.
Published: March 2023

Supplementary Figure Legends - PDF file 59K, Figure legends for Sup. Figures 1 and 2
Supplementary Methods from Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation
Authors: Popova Tatiana , Manié Elodie , Rieunier Guillaume , Caux-Moncoutier Virginie , Tirapo Carole , Dubois Thierry , Delattre Olivier , Sigal-Zafrani Brigitte , Bollet Marc , Longy Michel , Houdayer Claude , Sastre-Garau Xavier , Vincent-Salomon Anne , Stoppa-Lyonnet Dominique , Stern Marc-Henri
Published: March 2023

PDF file - 2.35MB, Experimental set of 65 BLCs, Processing SNP-arrays, Inferring chromosome number, Detection of tumor ploidy, Breakpoints estimation, Validation of LSTs by Next Generation Sequencing and Sanger sequencing, Features of LSTs, Distribution of LSTs along the genome, LSTs in detection of BRCA1 tumors in Experimental and Validation sets, Somatic BRCA1 mutations detected in BLCs with high LST, BRCA2 mutations detected in BLCs with high LST, Triple negative cell lines, & Stability of LSTs in xenograft passages as compared to primary tumors.
Supplementary Figures S1-S9 from Plastin3 Is a Novel Marker for Circulating Tumor Cells Undergoing the Epithelial–Mesenchymal Transition and Is Associated with Colorectal Cancer Prognosis
Authors: Yokobori Takehiko , Iinuma Hisae , Shimamura Teppei , Imoto Seiya , Sugimachi Keishi , Ishii Hideshi , Iwatsuki Masaaki , Ota Daisuke , Ohkuma Masahisa , Iwaya Takeshi , Nishida Naohiro , Kogo Ryunosuke , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Toh Hiroyuki , Sato Tetsuya , Barnard Graham F. , Fukagawa Takeo , Yamamoto Seiichiro , Nakanishi Hayao , Sasaki Shin , Miyano Satoru , Watanabe Toshiaki , Kuwano Hiroyuki , Mimori Koshi , Pantel Klaus , Mori Masaki
Published: March 2023

Supplementary Figures S1-S9 PDF file - 984K, Representative photomicrographs of tissue sections immunostained for PLS3 (S1); The clinical significance of PLS3 expression in a second independent set of 110 primary colorectal cancer samples (S2); PLS3 expression profiles in various tissues, including peripheral blood-derived cells (S3); EMT induction in CaR-1 cells by TGF-beta1 (S4); PLS3 mRNA expression in LoVo cells expressing stem cell makers (S5); Immunocytochemical staining of PLS3 in rectal cancer cell line CaR-1 and peripheral blood mononuclear cells (S6); Validation of PLS3 expression in PB after recurrence (S7); Survival curves of Dukes stage B CRC patients based on the level of CK19/CK20 mRNA expression in PB (S8); PLS3 expression profiles in several cancer cell lines (S9)
Supplementary Figure 3 from RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Authors: Wang Hongyan , Liu Kaihua , Geng Miao , Gao Peng , Wu Xiaoyuan , Hai Yan , Li Yangxia , Li Yulong , Luo Lin , Hayes John D. , Wang Xiu Jun , Tang Xiuwen
Published: March 2023

PDF file - 188K, RXRa interacted with Nrf2 in vivD.
Supplementary Figure S6 from Mitogenic Insulin Receptor-A Is Overexpressed in Human Hepatocellular Carcinoma due to EGFR-Mediated Dysregulation of RNA Splicing Factors
Authors: Chettouh Hamza , Fartoux Laetitia , Aoudjehane Lynda , Wendum Dominique , Clapéron Audrey , Chrétien Yves , Rey Colette , Scatton Olivier , Soubrane Olivier , Conti Filomena , Praz Françoise , Housset Chantal , Rosmorduc Olivier , Desbois-Mouthon Christèle
Published: March 2023

Supplementary Figure S6 - PDF file 371K, EGFR-dependent signalling increases IR-A mRNA splicing in colon cancer cell lines
Supplementary Figure 2 from RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Authors: Wang Hongyan , Liu Kaihua , Geng Miao , Gao Peng , Wu Xiaoyuan , Hai Yan , Li Yangxia , Li Yulong , Luo Lin , Hayes John D. , Wang Xiu Jun , Tang Xiuwen
Published: March 2023

PDF file - 572K, Cellular co-localization of ectopic GFP and RFP in HEK293T cells.
Supplementary Video 1 from Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors
Authors: Manzoor Ashley A. , Lindner Lars H. , Landon Chelsea D. , Park Ji-Young , Simnick Andrew J. , Dreher Matthew R. , Das Shiva , Hanna Gabi , Park Won , Chilkoti Ashutosh , Koning Gerben A. , ten Hagen Timo L.M. , Needham David , Dewhirst Mark W.
Published: March 2023

AVI file - 41.7MB, Real-time drug delivery of free doxorubicin and Dox-TSL in heated FaDu tumor tissue. The blood vessels are highlighted in green and drug is red. The video shows drug delivered over the first 20min, at 20x magnification. Free drug quickly disperses throughout the tissue and then is reabsorbed into the vasculature, leaving a low drug concentration behind in the tumor cells. In the Dox-TSL treated tissue, drug is delivered uniformly across the tumor tissue, with visible uptake in tumor and endothelial cell nuclei. Drug in the Dox-TSL treated mouse continues to accumulate in the tumor tissue over the 20min period. (Download before playing in IE8)
Supplementary Tables & Figures from MEK1/2 Inhibition Decreases Lactate in BRAF-Driven Human Cancer Cells
Authors: Falck Miniotis Maria , Arunan Vaitha , Eykyn Thomas R. , Marais Richard , Workman Paul , Leach Martin O. , Beloueche-Babari Mounia
Published: March 2023

Supplementary Tables & Figures - PDF file 354K, Table S1: The amount of glucose left in the media relative to controls following 24h treatment with CI-1040 as measured by 1H MRS. Fig.S1: The effect of 0-2% DMSO treatment for 24h on cell cycle, MEK1/2 signaling and lactateE in BRAFV600D WM266.4 cells. Fig.S2: The effect of 24h treatment with carboplatin on cell cycle profiles (A), cell counts and lactateE levels (B) in BRAFV600D WM266.4 human melanoma cells.*p<0.05, n=4. Fig.S3: The effect of 24h CI-1040 and PD325901 treatment on MEK1/2 signaling, cell proliferation and cell cycle distributions in human cancer cells with varying BRAF mutation status. Fig.S4: MEK1/2 inhibition with CI-1040 (1�M, 24h) reduces hexokinase-II expression in BRAFV600E HT29 human colon cancer cells. *p=0.02, n=3. Fig.S5: Western blots showing no effect on P-AKT levels in BRAFV600D WM266.4 melanoma cells following treatment with CI-1040 (1�M). N=3
Supplementary Figure 1 from Bevacizumab-Induced Normalization of Blood Vessels in Tumors Hampers Antibody Uptake
Authors: Arjaans Marlous , Oude Munnink Thijs H. , Oosting Sjoukje F. , Terwisscha van Scheltinga Anton G.T. , Gietema Jourik A. , Garbacik Erik T. , Timmer-Bosscha Hetty , Lub-de Hooge Marjolijn N. , Schröder Carolina P. , de Vries Elisabeth G.E.
Published: March 2023

PDF file - 53K, Biodistribution of 89Zr-Trastuzumab in the OE19 model and correlation of the in vivo PET tumor uptake with the ex vivo biodistriution tumor uptake of 89Zr-trastuzumab in the OE19 model.
Supplementary Methods, Figure Legends 1-8 from SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression
Authors: Zhang Jianchao , Liang Qian , Lei Yang , Yao Min , Li Lili , Gao Xiaoge , Feng Jingxin , Zhang Yu , Gao Hongwen , Liu Dong-Xu , Lu Jun , Huang Baiqu
Published: March 2023

PDF file - 207K
Supplementary Figures 6-8 from SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression
Authors: Zhang Jianchao , Liang Qian , Lei Yang , Yao Min , Li Lili , Gao Xiaoge , Feng Jingxin , Zhang Yu , Gao Hongwen , Liu Dong-Xu , Lu Jun , Huang Baiqu
Published: March 2023

PDF file - 3.4MB, Figure S6. SOX4 alone was unable to induce tumor formation. Figure S7. Silencing of SOX4 reversed the EMTs in SOX4-expression MCF10A cells. Figure S8. Relative SOX4 mRNA expression levels in NMuMG cells treated with activated TGF-beta1 at indicated time and concentrations.
Supplementary Figure 1 from Natural Product Triptolide Mediates Cancer Cell Death by Triggering CDK7-Dependent Degradation of RNA Polymerase II
Authors: Manzo Stefano Giustino , Zhou Zhao-Li , Wang Ying-Qing , Marinello Jessica , He Jin-Xue , Li Yuan-Chao , Ding Jian , Capranico Giovanni , Miao Ze-Hong
Published: March 2023

PDF file - 1.1MB, Cells were treated with gradient concentrations of triptolide, then harvested by Western blotting
Supplementary Figure 7 from Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
Authors: Richards Juliet , Lim Ai Chiin , Hay Colin W. , Taylor Angela E. , Wingate Anna , Nowakowska Karolina , Pezaro Carmel , Carreira Suzanne , Goodall Jane , Arlt Wiebke , McEwan Iain J. , de Bono Johann S. , Attard Gerhardt
Published: March 2023

PDF file - 121K
Supplementary Figure 3 from Epithelial Cell Organization Suppresses Myc Function by Attenuating Myc Expression
Authors: Simpson David R. , Yu Min , Zheng Siyuan , Zhao Zhongming , Muthuswamy Senthil K. , Tansey William P.
Published: March 2023

Supplementary Figure 3 from Epithelial Cell Organization Suppresses Myc Function by Attenuating Myc Expression
Supplementary Methods, Figures 1-5, Table 1 from Spatiotemporal Assessments of Dermal Hyperemia Enable Accurate Prediction of Experimental Cutaneous Carcinogenesis as well as Chemopreventive Activity
Authors: Konger Raymond L. , Xu Zhengbin , Sahu Ravi P. , Rashid Badri M. , Mehta Shama R. , Mohamed Deena R. , DaSilva-Arnold Sonia C. , Bradish Joshua R. , Warren Simon J. , Kim Young L.
Published: March 2023

PDF file - 690K, Foci of persistent dermal hyperemia reliably predict where murine cutaneous neoplasia will develop as well as the chemopreventive activity of Celexocib treatment
Supplementary Figure 4 from RORα Suppresses Breast Tumor Invasion by Inducing SEMA3F Expression
Authors: Xiong Gaofeng , Wang Chi , Evers B. Mark , Zhou Binhua P. , Xu Ren
Published: March 2023

PDF file - 1730K
Supplementary Figure 3 from RORα Suppresses Breast Tumor Invasion by Inducing SEMA3F Expression
Authors: Xiong Gaofeng , Wang Chi , Evers B. Mark , Zhou Binhua P. , Xu Ren
Published: March 2023

PDF file - 2.3MB
Supplementary Table 6 from Extensive Promoter DNA Hypermethylation and Hypomethylation Is Associated with Aberrant MicroRNA Expression in Chronic Lymphocytic Leukemia
Authors: Baer Constance , Claus Rainer , Frenzel Lukas P. , Zucknick Manuela , Park Yoon Jung , Gu Lei , Weichenhan Dieter , Fischer Martina , Pallasch Christian Philipp , Herpel Esther , Rehli Michael , Byrd John C. , Wendtner Clemens-Martin , Plass Christoph
Published: March 2023

PDF file - 26K, Table S6 contains qPCR-based expression data of candidate miRNAs in different healthy tissues
Supplementary Table 2 from Extensive Promoter DNA Hypermethylation and Hypomethylation Is Associated with Aberrant MicroRNA Expression in Chronic Lymphocytic Leukemia
Authors: Baer Constance , Claus Rainer , Frenzel Lukas P. , Zucknick Manuela , Park Yoon Jung , Gu Lei , Weichenhan Dieter , Fischer Martina , Pallasch Christian Philipp , Herpel Esther , Rehli Michael , Byrd John C. , Wendtner Clemens-Martin , Plass Christoph
Published: March 2023

PDF file - 23K, Table S2 contains primer sequences for MassARRAY-based DNA methylation analyses
Supplementary Table 1 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells
Authors: Shien Kazuhiko , Toyooka Shinichi , Yamamoto Hiromasa , Soh Junichi , Jida Masaru , Thu Kelsie L. , Hashida Shinsuke , Maki Yuho , Ichihara Eiki , Asano Hiroaki , Tsukuda Kazunori , Takigawa Nagio , Kiura Katsuyuki , Gazdar Adi F. , Lam Wan L. , Miyoshi Shinichiro
Published: March 2023

PDF file - 73K, List of Primers and TaqMan assays.
Supplementary Figure 1 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells
Authors: Shien Kazuhiko , Toyooka Shinichi , Yamamoto Hiromasa , Soh Junichi , Jida Masaru , Thu Kelsie L. , Hashida Shinsuke , Maki Yuho , Ichihara Eiki , Asano Hiroaki , Tsukuda Kazunori , Takigawa Nagio , Kiura Katsuyuki , Gazdar Adi F. , Lam Wan L. , Miyoshi Shinichiro
Published: March 2023

PDF file - 170K, Genotypic mechanisms of acquired resistance to EGFR-TKI.
Supplementary Figures 1-9 from Oncogenicity of the Developmental Transcription Factor Sox9
Authors: Matheu Ander , Collado Manuel , Wise Clare , Manterola Lorea , Cekaite Lina , Tye Angela J. , Canamero Marta , Bujanda Luis , Schedl Andreas , Cheah Kathryn S.E. , Skotheim Rolf I. , Lothe Ragnhild A. , López de Munain Adolfo , Briscoe James , Serrano Manuel , Lovell-Badge Robin
Published: March 2023

PDF file - 649K
Supplementary Table 1 from HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
Authors: Nowsheen Somaira , Cooper Tiffiny , Bonner James A. , LoBuglio Albert F. , Yang Eddy S.
Published: March 2023

PDF file - 40K, Gene cluster, ER, PR and p53 status of the various HER2+ breast cancer cell lines ((3) and COSMIC database)
Supplementary Figure 1 from A Multistage Association Study Identifies a Breast Cancer Genetic Locus at NCOA7
Authors: Higginbotham Kathryn S.P. , Breyer Joan P. , Bradley Kevin M. , Schuyler Peggy A. , Plummer W. Dale , Freudenthal Marcia E. , Trentham-Dietz Amy , Newcomb Polly A. , Sanders Melinda E. , Page David L. , Parl Fritz F. , Egan Kathleen M. , Dupont William D. , Smith Jeffrey R.
Published: March 2023

Supplementary Figure 1 from A Multistage Association Study Identifies a Breast Cancer Genetic Locus at NCOA7
Supplementary Figure 6 from TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Authors: Yang Yonghong , Wang Xingmin , Moore Danny R. , Lightfoot Stanley A. , Huycke Mark M.
Published: March 2023

PDF file - 382K, showing NF-kappaB/p65 staining for 3 months biopsies
Supplementary Figure 5 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 339K
Supplementary Figure 2 from TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Authors: Yang Yonghong , Wang Xingmin , Moore Danny R. , Lightfoot Stanley A. , Huycke Mark M.
Published: March 2023

PDF file - 722K, showing macrophage and TNF-alpha staining for 3 months biopsies
Supplementary Figure 2 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 387K
Supplementary Tables 1-2 from The Metabolomic Signature of Malignant Glioma Reflects Accelerated Anabolic Metabolism
Authors: Chinnaiyan Prakash , Kensicki Elizabeth , Bloom Gregory , Prabhu Antony , Sarcar Bhaswati , Kahali Soumen , Eschrich Steven , Qu Xiaotao , Forsyth Peter , Gillies Robert
Published: March 2023

PDF file - 69K, Table S1. Tumor grade and histology of samples used for global metabolomic profiling. Table S2. Metabolites making up the identified metabolomic profiles that demonstrated statistical significance in malignant glioma
Supplementary Table 3 from The Metabolomic Signature of Malignant Glioma Reflects Accelerated Anabolic Metabolism
Authors: Chinnaiyan Prakash , Kensicki Elizabeth , Bloom Gregory , Prabhu Antony , Sarcar Bhaswati , Kahali Soumen , Eschrich Steven , Qu Xiaotao , Forsyth Peter , Gillies Robert
Published: March 2023

PDF file - 609K, Kruskal-Wallis test for transciptional differences in metabolic subtypes
Supplementary Table 5 from Distinct Patterns of Dysregulated Expression of Enzymes Involved in Androgen Synthesis and Metabolism in Metastatic Prostate Cancer Tumors
Authors: Mitsiades Nicholas , Sung Clifford C. , Schultz Nikolaus , Danila Daniel C. , He Bin , Eedunuri Vijay Kumar , Fleisher Martin , Sander Chris , Sawyers Charles L. , Scher Howard I.
Published: March 2023

PDF file - 14K, Transcripts most-highly co-regulated with AKR1C3 in primary and metastatic PCas (top list: positive association; bottom list: negative association)
Supplementary Figures 1-4 from The Metabolomic Signature of Malignant Glioma Reflects Accelerated Anabolic Metabolism
Authors: Chinnaiyan Prakash , Kensicki Elizabeth , Bloom Gregory , Prabhu Antony , Sarcar Bhaswati , Kahali Soumen , Eschrich Steven , Qu Xiaotao , Forsyth Peter , Gillies Robert
Published: March 2023

PDF file - 237K, Figure S1. RF analysis was performed to determine the accuracy of metabolomic profiles in predicting glioma grade. Figure S2. Intra-sample concordance of glycolytic intermediates PEP and 3-PG in glioma. Figure S3. Glioma subtype classification based on transcriptional profiles was performed using unsupervised hierarchical clustering from a total of 35 probe sets, as described as Phillips et al. (15). Figure S4. PCA of each metabolic profile by plotting the first two components, indicating no discernable separation between transcriptional subtypes or grade.
Supplementary Legends for Figure 1 and Tables 1-5 from Distinct Patterns of Dysregulated Expression of Enzymes Involved in Androgen Synthesis and Metabolism in Metastatic Prostate Cancer Tumors
Authors: Mitsiades Nicholas , Sung Clifford C. , Schultz Nikolaus , Danila Daniel C. , He Bin , Eedunuri Vijay Kumar , Fleisher Martin , Sander Chris , Sawyers Charles L. , Scher Howard I.
Published: March 2023

PDF file - 68K
Supplementary Figure 5 from Oncolytic Virus and Anti–4-1BB Combination Therapy Elicits Strong Antitumor Immunity against Established Cancer
Authors: John Liza B. , Howland Linda J. , Flynn Jacqueline K. , West Alison C. , Devaud Christel , Duong Connie P. , Stewart Trina J. , Westwood Jenny A. , Guo Z. Sheng , Bartlett David L. , Smyth Mark J. , Kershaw Michael H. , Darcy Phillip K.
Published: March 2023

PDF file - 110K
Supplementary Figure 4 from Oncolytic Virus and Anti–4-1BB Combination Therapy Elicits Strong Antitumor Immunity against Established Cancer
Authors: John Liza B. , Howland Linda J. , Flynn Jacqueline K. , West Alison C. , Devaud Christel , Duong Connie P. , Stewart Trina J. , Westwood Jenny A. , Guo Z. Sheng , Bartlett David L. , Smyth Mark J. , Kershaw Michael H. , Darcy Phillip K.
Published: March 2023

PDF file - 104K
Supplementary Video 6 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: March 2023

MOV file - 2MB, Effects of MEK Inhibitor PD0325901 on Ras-driven luminal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive luminalRas/GFP (MMTV-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and PD0325901 in 3D
Supplementary Movie 3 from β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma
Authors: Carbonell W. Shawn , DeLay Michael , Jahangiri Arman , Park Catherine C. , Aghi Manish K.
Published: March 2023

MOV file - 1285K, Supplementary Movie 3. Epithelial Migration Of Bevacizumab-Na�ve Glioma Cells. Related to Figure 2. Timelapse phase-contrast imaging of N1 bevacizumab-na�ve (left) and BRG3 bevacizumab-resistant (right) cells on fibronectin. N1 cells demonstrated classic epithelial migration with broad lamellipodial extensions and slow rearward translocation with an overall polygonal morphology. In contrast, BRG3 cells display rapid, saltatory migration with spindle-like morphology. Movie images captured with a 40x objective representing approximately 14 hours of imaging, 35 minutes between each frame.
Supplementary Figure 3 from Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination
Authors: Aarntzen Erik H.J.G. , De Vries I. Jolanda M. , Lesterhuis W. Joost , Schuurhuis Danita , Jacobs Joannes F.M. , Bol Kalijn , Schreibelt Gerty , Mus Roel , De Wilt Johannes H.W. , Haanen John B.A.G. , Schadendorf Dirk , Croockewit Alexandra , Blokx Willeke A.M. , Van Rossum Michelle M. , Kwok William W. , Adema Gosse J. , Punt Cornelis J.A. , Figdor Carl G.
Published: March 2023

PDF file - 34K, KLH specific responses
Supplementary Figure 5 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF file - 60K, Schematic presentation of Ras-mediated Pak1 signaling
Supplementary Figure 4 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF file - 162K, Proliferation and apoptosis in drug-treated animals