bluuebunny/crossref_metadata_2025 huggingface dataset:
A novel hybrid triboelectric nanogenerator based on the mutual boosting effect of electrostatic induction and electrostatic breakdown
Authors: Chen Ai , Zeng Qixuan , Tan Liming , Xu Fan , Wang Tingyu , Zhang Xiaofang , Luo Yanlin , Wang Xue
Published: June 2023

A novel hybrid triboelectric nanogenerator integrating AC- and DF-triboelectric nanogenerators is developed, with a switchable dual-output feature, and the mutual boosting effect of electrostatic induction and electrostatic breakdown is identified.
Qualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater
Authors: Habumugisha Théogène , Zhang Zixing , Ndayishimiye Jean Claude , Nkinahamira François , Uwizewe Constance , Cyubahiro Eric , Rehman Abdul , Yan Changzhou , Zhang Xian
Published: June 2023

PSN-spiked water exposure medium facilitated the spread of PSN in zebrafish tissues. New developed methods of MALDI-TOF-MS enabled an accurate analysis of PSN features in an aquatic organism.
A versatile test system to determine nanomaterial heteroagglomeration attachment efficiency
Authors: Walch Helene , Bašić Nada , Praetorius Antonia , von der Kammer Frank , Hofmann Thilo
Published: June 2023

Test system to determine nanomaterial heteroagglomeration attachment efficiency for fate models and risk assessment.
Acetalization strategy in biomass valorization: a review
Authors: He Jian , Qiang Qian , Bai Li , Su Wentao , Yu Huazhong , Liu Shima , Li Changzhi
Published: June 2023

Acetalization serves as both a synthesis tool for renewable cyclic acetal fuel additives and a protection strategy to improve selectivity in biomass conversion.
In vivo self-assembled shape-memory polyurethane for minimally invasive delivery and therapy
Authors: Li Shifen , Zhang Hua , Xie Jieqi , Wang Zhaoyi , Wang Kai , Zhai Zihe , Ding Jie , Wang Shuqin , Shen Liyin , Wen Jun , Tang Yi-Da , Wang Huanan , Zhu Yang , Gao Changyou
Published: June 2023

Advanced elastomers are highly demanded for the fabrication of medical devices for minimally invasive surgery (MIS). A diselenide-containing, shape-memory and self-healing polyurethane for MIS is illustrated in myocardial infarction therapy.
Aggregation-induced type I&II photosensitivity and photodegradability-based molecular backbones for synergistic antibacterial and cancer phototherapy via photodynamic and photothermal therapies
Authors: Liu Jun , Chen Hongyu , Yang Yongsheng , Wang Qihui , Zhang Shilu , Zhao Bo , Li Zhonghui , Yang Guoqiang , Deng Guowei
Published: June 2023

A molecular backbone that induces type I/II photosensitivity and photodegradability by forming J-aggregates was developed, which can not only improve the safety but also the therapeutic effect of phototherapy.
Syngas production from the CO2 reforming of a waste cooking oil model compound over catalysts derived from La1−xSrxNiO3 perovskites
Authors: Hao Songyuan , Luo Wenbo , Kang Yaming , Fu Sen , Yuan Hong
Published: June 2023

A series of catalysts based on La1−xSrxNiO3 (x = 0.1, 0.2) perovskites were prepared for catalytic CO2 reforming of a waste cooking oil model compound.
Molecularly imprinted polymer-based dispersive solid-phase extraction for the selective determination of carisoprodol in biological and pharmaceutical samples
Authors: Manhas Sakshi , Bajaj Atul , Jain Bharti , Kumar Deepak , Singh Jaskaran , Shukla Saurabh , Jain Rajeev
Published: June 2023

A novel analytical technique based on a molecularly imprinted polymer coupled with dispersive solid-phase extraction is developed.
Towards a qualitative understanding of the carbonyl reactivity of α-substituted ethyl 5-oxohomoadamantyl-4-carboxylates
Authors: Tkachenko Ilya M. , Shiryaev Vadim A. , Klimochkin Yuri N.
Published: June 2023

Formal decarbethoxylation of α-quaternary β-ketoesters of homoadamantane series occurs upon treating with nucleophilic agents. Various substituted and heteroannulated homoadamantanes have been synthesized using N-centered nucleophilic agents.
Synthesis of 3-aminoquinolines from α-imino rhodium carbenes and 2-aminobenzaldehydes
Authors: Li Jiani , Feng Jing , Chen Tao , Xu Ze-Feng , Li Chuan-Ying
Published: June 2023

A straightforward process for the synthesis of valuable 3-aminoquinolines was reported starting from easily available triazoles and 2-aminobenzaldehydes.
A simple and efficient pathway for the total synthesis of marine natural products: bengamide E and 5-epi-bengamide E
Authors: Gupta Akanksha , Ambati Praveen , Perali Ramu Sridhar
Published: June 2023

An efficient synthetic strategy for bengamide E and 5-epi-bengamide E, utilizing a d-galactose derivative for the formation of the C10-polyhydroxylated side chain, has been reported via two routes.
Water soluble non-conjugated fluorescent polymers: aggregation induced emission, solid-state fluorescence, and sensor array applications
Authors: Jose Anna , Tharayil Adithya , Porel Mintu
Published: June 2023

In this work, two water soluble fluorescent non-conjugated polymers have been designed and synthesized.
Fabrication of heterostructured Pd-porphyrin MOFs/ZnIn2S4composites to boost photocatalytic hydrogen evolution under visible light irradiation
Authors: Wang Sheng , Feng Huiyi , Zheng Chenglong , Li Shihao , Fan Shilu , Feng Yi-Si
Published: June 2023

The Pd-PMOFs@ZIS heterostructures exhibit prominently enhanced photocatalytic hydrogen generation activity.
A review of fused-ring carbazole derivatives as emitter and/or host materials in organic light emitting diode (OLED) applications
Authors: Oner Saliha , Bryce Martin R.
Published: June 2023

This review focuses on fused-ring carbazole derivatives, their molecular design, electronic and photophysical properties, and their applications as the emitter and/or the host material in organic light emitting diodes (OLEDs).
Ultrasound-assisted degradation of organophosphorus pesticide methidathion using CuFe2O4@SiO2-GOCOOH as a magnetic separable sonocatalyst
Authors: Maati Houda , Amadine Othmane , Essamlali Younes , Aboulhrouz Soumia , jioui Ilham , Dânoun Karim , Zahouily Mohamed
Published: June 2023

Water contamination by pesticides is a critical environmental issue, necessitating the development of sustainable and efficient degradation methods.
Correction and removal of expression of concern: Ameliorative effect of biofabricated ZnO nanoparticles of Trianthema portulacastrum Linn. on dermal wounds via removal of oxidative stress and inflammation
Authors: Yadav Ekta , Singh Deepika , Yadav Pankajkumar , Verma Amita
Published: June 2023

Correction and removal of expression of concern for ‘Ameliorative effect of biofabricated ZnO nanoparticles of Trianthema portulacastrum Linn. on dermal wounds via removal of oxidative stress and inflammation’ by Ekta Yadav et al., RSC Adv., 2018, 8, 21621–21635, https://doi.org/10.1039/C8RA03500H.
Development of 8–17 XNAzymes that are functional in cells
Authors: Chiba Kosuke , Yamaguchi Takao , Obika Satoshi
Published: June 2023

Modified 8–17 DNAzymes that can induce target gene silencing in cells were developed based on the X-ray crystal structure of 8–17 DNAzyme and the modifications used in designing antisense oligonucleotides.
Diatomic catalysts for Fenton and Fenton-like reactions: a promising platform for designing/regulating reaction pathways
Authors: Mo Fan , Zhou Qixing , Li Chenghao , Tao Zongxin , Hou Zelin , Zheng Tong , Wang Qi , Ouyang Shaohu , Zhan Sihui
Published: June 2023

The summarized new advances and proposed research directions in this perspective can provide in-depth insights for the application/mechanism investigation of DAC-mediated Fenton/Fenton-like reactions.
Enhanced peroxidase-like activity of MOF nanozymes by co-catalysis for colorimetric detection of cholesterol
Authors: Li Shuishi , Liang Ling , Tian Longfei , Wu Jia , Zhu Yuhui , Qin Yuan , Zhao Shulin , Ye Fanggui
Published: June 2023

MoCu-2MI was synthesized using Mo-doped Cu-2MI and exhibited enhanced peroxidase-like activity through the co-catalytic Fenton reaction.
Perceived Factors That Facilitate or Prevent the Use of Speech-Generating Devices in Bilingual Individuals With Aphasia
Authors: Hung Pei-Fang , Brock Kris L. , Sun Lei , Hanson Jennifer , Larsen Sarah , Small Claire
Published: June 2023

Purpose:

The aim of this study was to explore practicing speech-language pathologists' (SLPs') perceptions of factors that could facilitate or prevent the use of speech-generating devices (SGDs) in bilingual individuals with aphasia. Specifically, this exploratory study sought to identify the facilitators and barriers to SGD use in individuals with culturally and linguistically diverse backgrounds.

Method:

An online survey was distributed to SLPs through an e-mail listserv and social media of an augmentative and alternative communication company. This article focused on the results of the survey items related to (a) the presence of bilingual individuals with aphasia on an SLP's caseload, (b) training related to SGD or bilingual aphasia, and (c) barriers and facilitators to SGD use. A thematic analysis was conducted to analyze the barriers and facilitators to SGD use reported by the respondents.

Results:

A total of 274 SLPs who met the inclusion criteria had experience in implementing SGD for people with aphasia. Regarding relevant training, our results indicated that very few SLPs received bilingual aphasia intervention training (17.22%) or bilingual SGD training (0.56%) in graduate school. The results from our thematic analysis revealed four major themes of barriers and facilitators to SGD use, including (a) hardware and software, (b) cultural and language content, (c) SLP's cultural and linguistic competency, and (d) resources.

Conclusions:

Practicing SLPs reported several barriers to SGD use in bilinguals with aphasia. Most notably, language barriers for monolingual SLPs were seen as the greatest barrier to language recovery in individuals with aphasia whose primary language is not English. Several other barriers were consistent with previous research, such as financial factors and insurance disparities. The top three most important factors that facilitate SGD use in bilinguals with aphasia, as identified by the respondents, include user-friendly symbol organization, personalized words, and ease of programming.
Multilingual Speech Acquisition by Vietnamese-English–Speaking Children and Adult Family Members
Authors: McLeod Sharynne , Verdon Sarah , Margetson Kate , Tran Van H. , Wang Cen , Phạm Ben , To Lily , Huynh Kylie
Published: June 2023

Purpose:

This article presents a large-scale example of culturally responsive assessment and analysis of multilingual Vietnamese-English–speaking children and their family members using the VietSpeech Protocol involving (a) examining all spoken languages, (b) comparing ambient phonology produced by family members, (c) including dialectal variants in the definition of accuracy, and (d) clustering participants with similar language experience.

Method:

The VietSpeech participants (N= 154) comprised 69 children (2;0–8;10 [years;months]) and 85 adult family members with Vietnamese heritage living in Australia. Speech was sampled using the Vietnamese Speech Assessment (Vietnamese) and the Diagnostic Evaluation of Articulation and Phonology (English).

Results:

Children's Vietnamese consonant accuracy was significantly higher when dialectal variants were accepted (percentage of consonants correct–dialect [PCC-D]:M= 87.76,SD= 8.18), compared to when only Standard Vietnamese was accepted as the correct production (percentage of consonants correct–standard [PCC-S]:M= 70.34,SD= 8.78), Cohen'sd= 3.55 (large effect). Vietnamese voiced plosives, nasals, semivowels, vowels, and tones were more often correct than voiceless plosives and fricatives. Children's Standard Australian English consonant accuracy (PCC-S) was 82.51 (SD= 15.57). English plosives, nasals, glides, and vowels were more often correct than fricatives and affricates. Vietnamese word-initial consonants had lower accuracy than word-final consonants, whereas English consonant accuracy was rarely influenced by word position. Consonant accuracy and intelligibility were highest for children with high proficiency in both Vietnamese and English. Children's consonant productions were most similar to their mothers' than other adults or siblings' productions. Adults' Vietnamese consonants, vowels, and tones were more likely to match Vietnamese targets than their children's productions.

Conclusions:

Children's speech acquisition was influenced by cross-linguistic, dialectal, maturational, language experience, and environmental (ambient phonology) factors. Adults' pronunciation was influenced by dialectal and cross-linguistic factors. This study highlights the importance of including all spoken languages, adult family members, dialectal variants, and language proficiency to inform differential diagnosis of speech sound disorders and identify clinical markers in multilingual populations.

Supplemental Material:

https://doi.org/10.23641/asha.23290055
Detecting Emotional Prosody in Real Words: Electrophysiological Evidence From a Modified Multifeature Oddball Paradigm
Authors: Kao Chieh , Zhang Yang
Published: June 2023

Purpose:

Emotional voice conveys important social cues that demand listeners' attention and timely processing. This event-related potential study investigated the feasibility of a multifeature oddball paradigm to examine adult listeners' neural responses to detecting emotional prosody changes in nonrepeating naturally spoken words.

Method:

Thirty-three adult listeners completed the experiment by passively listening to the words in neutral and three alternating emotions while watching a silent movie. Previous research documented preattentive change-detection electrophysiological responses (e.g., mismatch negativity [MMN], P3a) to emotions carried by fixed syllables or words. Given that the MMN and P3a have also been shown to reflect extraction of abstract regularities over repetitive acoustic patterns, this study employed a multifeature oddball paradigm to compare listeners' MMN and P3a to emotional prosody change from neutral to angry, happy, and sad emotions delivered with hundreds of nonrepeating words in a single recording session.

Results:

Both MMN and P3a were successfully elicited by the emotional prosodic change over the varying linguistic context. Angry prosody elicited the strongest MMN compared with happy and sad prosodies. Happy prosody elicited the strongest P3a in the centro-frontal electrodes, and angry prosody elicited the smallest P3a.

Conclusions:

The results demonstrated that listeners were able to extract the acoustic patterns for each emotional prosody category over constantly changing spoken words. The findings confirm the feasibility of the multifeature oddball paradigm in investigating emotional speech processing beyond simple acoustic change detection, which may potentially be applied to pediatric and clinical populations.
Explainable human‐in‐the‐loop healthcare image information quality assessment and selection
Authors: Li Yang , Ercisli Sezai
Published: June 2023

Smart healthcare applications cannot be separated from healthcare data analysis and the interactive interpretability between data and model. A human‐in‐the‐loop active learning approach is introduced to reduce the cost of healthcare data labelling by evaluating the information quality of unlabelled medical data and then screening the high informative samples. Specifically, focused on the extracted feature tensor of medical images, a new evaluation metric was proposed, called local feature information distance. Then, the whole feature information distance between two images can be obtained by seeking optimal matching of local feature information correlation based on the feature spatial traversal. Further, the feature information distance entropy (FIDE) method was proposed from the perspective of feature spatial distribution, which outperformed other related works. Many comparison and ablation experiments were carried out; the results showed that the proposed method can well distinguish the information quality of the unlabelled samples even facing different datasets. The stability, robustness, and generalisation of the proposed method were verified. Thus, this study provides some inspirations for healthcare data analysis and efficient management, such as eliminating redundancy and selective annotation.
CTHP: Selection for adoption of open‐source bioinformatics software based on a customised ISO 25010 quality model, three‐way decision and Delphi hierarchy process
Authors: Li Yuqi , Bian Yixin , Zhang Ziheng , Zhao Song , Liu Yiqi
Published: June 2023

The ever‐growing open‐source software tools in different domains increase the difficulty of software selection from the end‐users perspective. The process of evaluating, comparing, and selecting open‐source solutions is far from trivial. Especially, when additional requirements need to be considered, the existing methodologies will fail to adapt to the new tasks. The objective of this study is to present a solution for dealing with this issue. A novel approach, CTHP, is presented for the evaluation and selection of open‐source software in the Bioinformatics domain. First, the ISO 25010 quality model is chosen as the basis. This model is customised according to the special characteristics of the Bioinformatics applications. The customisation is done by extracting the quality factors from the Bioinformatics applications, weighting these factors from the viewpoints of both developers and end‐users, and adding them to the model. After that, Three‐way Decision and Delphi Hierarchy Process are integrated to assist in the selection for adoption. Finally, as a case study, the proposed approach is applied to assist the decision‐making process of two popular natural language processing frameworks in the Bioinformatics area. Our study is a valuable contribution since it provides a systematic way to document the decision‐making process and help the researchers and practitioners of Bioinformatics to make better decisions among the alternatives.
Environmental dependence of Type IIn supernova properties
Authors: Moriya Takashi J. , Galbany Lluís , Jiménez-Palau Cristina , Anderson Joseph P. , Kuncarayakti Hanindyo , Sánchez Sebastián F. , Lyman Joseph D. , Pessi Thallis , Prieto Jose L. , Kochanek Christopher S. , Dong Subo , Chen Ping
Published: June 2023

Type IIn supernovae occur when stellar explosions are surrounded by dense hydrogen-rich circumstellar matter. The dense circumstellar matter is likely formed by extreme mass loss from their progenitors shortly before they explode. The nature of Type IIn supernova progenitors and the mass-loss mechanism forming the dense circumstellar matter are still unknown. In this work, we investigate whether Type IIn supernova properties and their local environments are correlated. We use Type IIn supernovae with well-observed light curves and host-galaxy integral field spectroscopic data so that we can estimate both supernova and environmental properties. We find that Type IIn supernovae with a higher peak luminosity tend to occur in environments with lower metallicity and/or younger stellar populations. The circumstellar matter density around Type IIn supernovae is not significantly correlated with metallicity, so the mass-loss mechanism forming the dense circumstellar matter around Type IIn supernovae might be insensitive to metallicity.
Strong unique continuation from the boundary for the spectral fractional laplacian
Authors: De Luca Alessandra , Felli Veronica , Siclari Giovanni
Published: June 2023

We investigate unique continuation properties and asymptotic behaviour at boundary points for solutions to a class of elliptic equations involving the spectral fractional Laplacian. An extension procedure leads us to study a degenerate or singular equation on a cylinder, with a homogeneous Dirichlet boundary condition on the lateral surface and a non-homogeneous Neumann condition on the basis. For the extended problem, by an Almgren-type monotonicity formula and a blow-up analysis, we classify the local asymptotic profiles at the edge where the transition between boundary conditions occurs. Passing to traces, an analogous blow-up result and its consequent strong unique continuation property is deduced for the nonlocal fractional equation.
Manufacturing of WC-17Co 3D-objects by Laser Powder Bed Fusion followed by heat-treatment
Authors: Papy Kevin , Favre Julien , Sova Alexey , Borbely Andras , Bertrand Philippe , Staerck Jean-Marc
Published: June 2023

Conventional tungsten carbide (WC) cermet parts containing a cobalt matrix phase are generally produced via powder sintering. In this study it is shown that cermet parts can also be produced by laser powder bed fusion from WC-17Co powder precursor. Optimal process parameters were found for manufacturing without preheated building plate. Micro-structural analysis revealed noteworthy porosity fraction (1.41%) as well as the presence of small-scale cracks in the as-built specimens. It is further shown that most of these defects can be eliminated by heat treatment at ambient pressure or by hot isostatic pressing. Heat treatment also led to the dissolution of the fragile W2C phase. Hardness test results indicate that the performance of the AM parts was comparable to that of a reference produced via powder sintering. The work is a successful demonstration of manufacturing of cermet parts using laser powder bed fusion.
Psychological Counseling Ability of College Ideological and Political Educators Based on Root Theory Exploration of Structure
Authors: Zhang Wei
Published: June 2023

Psychological counseling for college students has become one of the important contents of ideological and political education in current universities. The responsibility of ideological and political education workers is not only to strengthen and improve the objective requirements of ideological and political education for college students, but also to comply with the requirements of the era of quality education and promote the comprehensive development of college students. Thus, this paper selects 15 ideological and political educators in School R as the objects of this research, uses the Grounded theory method, and uses the qualitative analysis software Nvivo10 to conduct coding analysis and classification of interview data. Finally, 17 ability factors from six dimensions were preliminarily extracted, and 260 ideological and political education workers were randomly selected to participate in the questionnaire survey. Structural equation modeling software was used to conduct confirmatory factor analysis on the samples, hoping to establish a theoretical model of psychological counseling ability for ideological and political education workers in universities.
The Linkage between Juvenile Delinquency and Progression of Socialization Under Social Psychology Perspective
Authors: Liu Yitao
Published: June 2023

The significant growth in adolescent delinquency over the last several years has raised the alarm, forcing many to consider what we can do in the face of this problem. The elements that contribute to the development of adolescent delinquency are multifaceted, both subjective and objective. Subjective variables for the creation of juvenile criminal psychology include a one-sided view of life and poor legal consciousness, immature cognitive structure, the dualism of emotional irritation and will, and mindless compliance. At the same time, poor family education, school education elements, and society’s negative effect are objective variables in the development of adolescent criminal psychology. Understanding the causes of juvenile delinquency and effectively preventing and regulating juvenile delinquency has become an essential societal concern that must be addressed in today’s society.
Cognitive appraisal and coping styles of college students’ English learning anxiety
Authors: Huang Mao , Yang Jiaxin
Published: June 2023

Nowadays, international communication is becoming more and more frequent. As an international language, English is being studied by college students in more and more countries and regions. In the process of college students’ English learning, anxiety is a psychological factor that has an important influence on the learning effect. When college students feel anxious about learning English, the different cognitive appraisals will lead to different coping styles, which will also affect the degree of anxiety and the learning effect of college students. Therefore, this research uses Chinese college students as the sample and adopts the method of a questionnaire survey to study the relationship among the degree of English learning anxiety, cognitive appraisal, and coping style of college students. It is found that college students tend to adopt more positive coping styles when facing English learning anxiety. Positive coping styles are significantly correlated with secondary appraisal, while negative coping styles are significantly correlated with primary appraisal. In the primary appraisal, the ‘threat’ factor is significantly different from the variables of gender and education of college students. In the secondary appraisal, there is a significant difference between the ‘control expectation’ factor and the educational background variable. The research could provide some evidence support for the intervention of college students’ English learning anxiety in the future.
On the Role of Peer Review in the Teaching of Second Language Writing
Authors: Feng Linlin
Published: June 2023

After process writing entered the field of second language writing instruction, peer review, which is one of the central elements of the review and revision stages, has received increasing attention and research. Peer review is a very important factor in process writing, enriching the teaching activities of second language writing instruction and playing an indispensable role in second language writing. Peer review can help teachers provide better diagnostic feedback, which not only reflects teachers’ teaching results and students’ own understanding of the target language, but also has a significant impact on learners’ learning efficiency and motivation, and can positively influence learners’ writing habits. However, peer review also has its shortcomings and limitations that need to be noted, such as: (1) students tend to ignore the meaningful aspects of their peers’ writing; (2) discussions in peer assessment become “idle chatter”; (3) students are reluctant to make suggestions for their peers under the principle of “saving face”. (3) students are not willing to make suggestions for their peers. This paper discuss the benefits of peer review in second language writing teaching from the perspective of two different subjects, students and teachers, and conclude that peer review can encourage students to revise their work, enhance their sense of readership, strengthen their communicative competence, and reduce their learning anxiety; it can also help teachers to reduce their burden and solve their teaching problems.
Study on the Content and Implementation of the Ideological and Political Theories Education in Mechanics of Materials
Authors: Ren Qiufei , Su Wenzheng
Published: June 2023

The integration of ideological and political education in all courses needs the synergistic combination of professional courses with ideological and political courses. Based on the law of the personnel cultivation process and the nature of Mechanics of Materials, this paper proposes that the focus of ideological and political teaching in Mechanics of Materials is to guide students to master and apply Marxist standpoints and methodologies consciously to analyze and solve problems and develop noble scientific spirits. Taking the chapter Bending Stress as an example, the course design and implementation methods of ideological and political education in Mechanics of Materials are discussed in detail.
Research on the Teaching Implementation of Ideological and Political Theory Course in Higher Vocational Colleges with “Five Bases, Two Lines, and Four Alls” as the Core: A Case Study of the Theme-based Teaching Content of the Mao Zedong Thought and Introduction to Theoretical System of Socialism with Chinese Characteristics
Authors: Wang Lin
Published: June 2023

Based on the teaching design centered on “five bases” (i.e., the type-based teaching philosophy, concretization-based teaching objectives, theme-based teaching content, professionalism-based teaching strategies, and two-way-based teaching evaluation), the implementation of teaching innovation concerning ideological and political theory course in higher vocational colleges is mainly aimed at creating an online-offline mixed linkage pattern, and using the systematic thinking to carry out the teaching implementation process characterized by “four alls” (i.e., all-member problem investigation, all-around organization model, all-chain production-education integration, and all-process data analysis). On the whole, the implementation of the above-mentioned teaching innovation is committed to promoting the effective aggregation of element units with teachers and students as the common subject, as well as innovating and connecting resource carriers in series with theory as the axis. To this end, the global vision should be used to design the structure of the teaching ecosystem, plan the corresponding operation mode and assessment mechanism, and promote the dynamic and balanced operation of the curriculum teaching ecosystem, with a view to improving quality and enhancing efficiency as well as effectively serving the talent cultivation.
The orientation and development of Chinese university students’ ideological and moral education in the age of artificial Intelligence
Authors: Wang Lin , Qu Xinming
Published: June 2023

The application of artificial intelligence in the ideological and moral education of Chinese universities is an inevitable trend of the development of science and technology and The Times. Artificial Intelligence(AI) is not only the environmental constraint variable of ideological and moral education innovation, but also the driving factor of innovation process. AI drives the integrated development of information technology and ideological and moral education, enhances the affinity of ideological and moral education, and promotes the precision of ideological and moral education. Ideological and moral education should always aim at the social changes driven by artificial intelligence, and strive to cultivate new people who can compete and cooperate with robots.
The Path of Cultivating English Core Literacy in Higher Vocational Education in the Context of New Curriculum Standard
Authors: Xiangyu Kan
Published: June 2023

Higher vocational students have problems such as weak English language foundation, poor independent learning, weak awareness of multicultural communication, and insufficient communication skills in the foreign-related workplace. In view of these problems, according to the requirements of English Curriculum Standard for Higher Vocational Education (2021 Edition) for cultivating English core literacy in higher vocational education, this paper has proposed the strategies of reforming the curriculum, implementing mixed teaching, constructing typical foreign-related workplace scenarios and strengthening off-campus internship practice to integrate the concept of cultivating English core literacy into the whole process of curriculum teaching, in which way the humanity and instrumentality of vocational English curriculum can be achieved.
Research on communicating effect of ideological and political education on Wechat public accounts in universities
Authors: Shu Xiaodong
Published: June 2023

In order to explore the communicating effect of ideological and political education on Wechat public accounts in and universities, this paper evaluates the communicating effect from five aspects of ideological education, political education, moral education, psychological education and legal discipline education through empirical methods. The results show that the communicating effect of ideological and political education on Wechat public accounts in universities is general. There is no significant difference in the dimensions of gender and political status, but there are significant differences in grade and major. In view of the problems of different communicating effects in different grades and majors, it is suggested that educators should pay more attention to the political literacy and mental health education of undergraduates, innovate the educational methods of different majors, contact relevant colleges for educational linkage, and constantly improve the educational effects.
Research on Integration of Regional Red Culture into Ideological and Political Education Paths in Higher Vocational Colleges
Authors: Liu Yuanyuan
Published: June 2023

This paper takes regional red culture as an example and applies various research methods, including literature research, survey research, and teaching practice research, to examine the importance of integrating regional red culture into the ideological and political education curriculum in higher vocational colleges. By adopting strategies such as rational inheritance, emotional resonance, atmosphere creating, platform building, and autonomous researching and learning, the study analyzes how regional red culture can be effectively integrated into the ideological and political education in higher vocational colleges, with the ultimate goal of promoting cultural confidence and nurturing individuals with a strong sense of core socialist values.
Exploring the Cultivation of Continuous Learning Ability for Vocational College Students under the Background of Integration of Industry and Education
Authors: Li Ze
Published: June 2023

The integration of industry and education is the institutional guarantee of combining majors with industries, achieving complementary advantages between enterprises and schools, and achieving the integrated development of education and industry. The continuous guidance of policies has made it a reality for enterprises and schools to deeply participate in the integration of industry and education, school enterprise cooperation, and improve the quality of technical and skilled talent cultivation. In the spring breeze of vigorous development of vocational education, how to make vocational college students adapt to the requirements of the times and grow into the backbone of building a socialist modernized country has become a hot topic of discussion. This article explores the cultivation of continuous learning ability for vocational college students in the context of integration of industry and education, providing ideas for the cultivation of high-quality talents in vocational colleges.
Peripartum Haemorrhage, Diagnosis and Therapy. Guideline of the
DGGG, OEGGG and SGGG (S2k, AWMF Registry No. 015-063, August 2022)
Authors: Schlembach Dietmar , Annecke Thorsten , Girard Thierry , Helmer Hanns , Kainer Franz , Kehl Sven , Korte Wolfgang , Kühnert Maritta , Lier Heiko , Mader Silke , Mahnken Andreas , Maul Holger , Pfanner Georg , Ramsell Andrea , Surbek Daniel , Tiebel Oliver , Zinßer Laura , von Heymann Christian
Published: June 2023

Aim This official guideline was coordinated and published by the German Society of
Gynaecology and Obstetrics (DGGG). The guideline aims to provide a consensus-based
overview of the diagnosis and management of peripartum bleeding based on an evaluation of
the relevant literature.

Methods This S2k-guideline was developed by representative members from different
medical professions on behalf of the guidelines commission of the DGGG, OEGGG and SGGG
using a structured consensus process.

Recommendations Recommendations for the definition, risk stratification,
prevention, treatment (general emergency procedures, medications, uterine tamponade,
surgical measures, interventional-radiological procedures, haemostasis, and coagulation
management), transportation, documentation and debriefing as well as training are
presented. In addition, a PPH algorithm for action, “PPH 2022”, is recommended.
Involuntary Movements in Cobalamin Deficiency
Authors: Özyürek Hamit , Ince Hulya , Tasdemir Haydar Ali , Aydin Omer Faruk
Published: June 2023

Objective Neurologic problems are frequently described in infants with
nutritional vitamin B12 (cobalamin) deficiency.Major neurologic consequences of
infantile cobalamin deficiency include delays or regression in neurodevelopment
and the occurrence of involuntary movements

Methods We reviewed the medical records of infants with cobalamin
deficiency and divided infants with involuntary movements into two groups as
those, who developed involuntary movements during vitamin B12 supplementation
(Group I) and those, who developed involuntary movements prior to
supplementation therapy (Group II).

Results We evaluated a total of 32 infants with the diagnosis of cobalamin
deficiency. Involuntary movements were observed in 12 out of 32 infants. Group I
and Group II consisted of 6 infants each. Of the infants with involuntary
movements, five were exclusively breastfed until the time of diagnosis. The
majority of infants in Group II had choreoathetoid movements; twitching and
myoclonus in the face, tongue, and lips, and tremor in the upper extremities.
These involuntary movements disappeared in one to three weeks after clonazepam
therapy. In Group I; shaking movements, myoclonus, tremor, and twitching or
protrusion were observed in patients’ hands, feet, tongue, and lips on
the 3rd-5th day of cobalamin supplementation. These involuntary movements
disappeared within 5–12 days of clonazepam therapy.

Conclusion Recognition of nutritional cobalamin deficiency is important to
perform a differential diagnosis of the condition from seizures or other causes
of involuntary movements and avoid aggressive therapy and over treatment.
Sustaining Traditional Ethnomedicinal Knowledge and Protected Areas in Synergy: A Case Study of Overa-Aru Wildlife Sanctuary in Kashmir Himalaya
Authors: Islam Tajamul , Nawchoo Irshad A. , Magray Junaid A. , Khuroo Anzar Ahmad
Published: June 2023

The ethnic communities living near protected areas are critically dependent on medicinal plants for their healthcare. Although several ethnomedicinal studies are available from the
Himalaya, quantitative studies focusing on protected areas in this region are largely overlooked. In this study, we aimed to document the ethnomedicinal plants of the Overa-Aru wildlife
sanctuary in Kashmir Himalaya. We conducted a systematic field survey in the study area during 2020 – 2021 to collect primary data from 110 participants through semi-structured interviews
and questionnaires. The data was analyzed using quantitative indices and Pearsonʼs correlation. We recorded 64 plant species used against 8 human disease categories, including some
first-time reports from the region. Asteraceae and Lamiaceae were the most dominant families and herbs were the dominant growth form. The most common plant part used were leaves, and the
main method of preparation was decoction. Plant species with the highest relative frequency of citation was Achillea millifolium (0.83). Informant consensus factor for each disease
category ranged from 0.94 to 0.97. We found a strong positive correlation between participantsʼ age and citations (r = 0.85), but a negative correlation between the participantsʼ
education status and citations (r = − 0.11). Our results revealed that the younger generation possesses the least ethnomedicinal information. We recommend that the species with high
use values and fidelity level merit priority in phytochemical and pharmaceutical studies. Our findings highlight that protected areas, besides their prime importance in biodiversity
conservation, play a pivotal role in providing the healthcare provisioning ecosystem services to the ethnic communities.
Reconstruction of a Severe Open Tibiofibular Fracture using an Ipsilateral Vascularized Fractured Fibula with a Thoracodorsal Artery Perforator Free Flap
Authors: Chang Lan Sook , Kim Dae Kwan , Park Ji Ah , Hwang Kyu Tae , Kim Youn Hwan
Published: June 2023

The Gustilo IIIB tibiofibular fractures often result in long bone loss and extensive soft tissue defects. Reconstruction of these complex wounds is very challenging, especially when it includes long bone grafts, because the donor site is limited. We describe our experience using a set of chimeric ipsilateral vascularized fibula grafts with a thoracodorsal artery perforator free flap to reconstruct the traumatic tibia defects. A 66-year-old male suffered a severe comminuted tibia fracture and segmented fibula fracture with large soft tissue defects as a result of a traffic accident. He also had an open calcaneal fracture with soft tissue defects on the ipsilateral side. All the main vessels of the lower extremity were intact, and the cortical bone defect of the tibia was almost as large as the fractured fibula segment. We used an ipsilateral vascularized fibula graft to reconstruct the tibia and a thoracodorsal artery perforator flap to resurface the soft tissue, using the distal ends of peroneal vessels as named into sequential chimeric flaps. After 3 weeks, the calcaneal defect was reconstructed with second thoracodorsal artery perforator free flap. Reconstruction was successful and allowed rapid rehabilitation because of reduced donor site morbidity.
Synthesis of Aliphatic Nitriles via Desulfonylative Smiles Rearrangement
Authors: Abe Masahiro , Inamoto Kiyofumi , Jitsumatsu Honoka , Araki Mikoto , Mizukami Akiho , Kimachi Tetsutaro
Published: June 2023

Herein, we demonstrate the synthesis of aliphatic nitriles from N-acyl (2-nitrophenyl)sulfonamides via a desulfonylative Smiles rearrangement. The developed reaction routes provide a variety of aliphatic nitriles containing primary, secondary, and tertiary carbon centers in good-to-excellent yields. Our method requires the use of the easy-to-handle reagent potassium acetate and solvent 1,3-dimethyl-2-imidazolidinone, and it does not rely on toxic metal cyanides or transition metals. The process is suitable for large-scale reaction and for one-pot syntheses starting from an acyl chloride or a carboxylic acid.
Cluster Preface: Special Issue Honoring Masahiro Murakami’s Contributions to Science
Authors: Martin Ruben
Published: June 2023

Ruben Martin (left) was born in Barcelona in 1976. After receiving his PhD at the Universitat de Barcelona with Prof. Antoni Riera, he moved in January 2004 to the Max-Planck-Institut für Kohlenforschung, Mülheim, as a Humboldt postdoctoral fellow with Prof. Alois Fürstner, where he worked on iron cross-coupling reactions. In May 2005, he undertook further postdoctoral studies at the Massachusetts Institute of Technology with Prof. Stephen L. Buchwald where he developed new metal-catalyzed C–C and C–N bond-forming reactions. In September 2008, he initiated his independent career as an Assistant Professor at ICIQ (Tarragona). In July 2013, he was promoted to Associate Professor and subsequently to ICREA Research Professor. His research interests concern the discovery and development of synthetically useful organo­metallic methodologies.

Masahiro Murakami (right) studied chemistry at the University of ­Tokyo under the supervision of Professor Mukaiyama, receiving his doctoral degree in science in 1984. He started his career with a research assistant position to Professor Mukaiyama at the same place. In 1987, he moved to Kyoto University to take a research assistant position to the late Professor Yoshihiko Ito (1937–2006). He took a leave from May in 1991 to March in 1992 to work for Professor Albert Eschenmoser at ETH Zürich as a post-doctoral fellow. He then returned to Kyoto, being promoted to Associate Professor in 1993 and Professor in 2002. In March 2022, he retired from Kyoto University. His research interests include the development of synthetically useful, yet mechanistically interesting, organic sections, and the utilization of photo-energy for organic synthesis.
Acupuncture Clinical Trials on Knee Osteoarthritis
Authors: Gong Changzhen
Published: June 2023

The outcomes of eight acupuncture clinical trials on knee osteoarthritis were published in well-regarded English-language mainstream medical journals between 1975 and 2022. Reported trial results were equally balanced between positive and negative outcomes, thus producing an overall impression of ambiguity in regard to the efficacy of acupuncture in the treatment of knee osteoarthritis. This paper reviews these trials, analyzes the factors taken into account in each trial, and has posited two reasons for the continuing lack of consensus in regard to the medical effectiveness of acupuncture: the difficulty of designing scientifically consistent clinical-trial studies; and an institutional bias toward ambiguity on the part of scientific and medical journals.
Pituitary Hormonal Disturbances in Aneurysmal Subarachnoid Hemorrhage
Authors: Moura Jose Carlos de , Azevedo Hildo Rocha Cirne de , Valença Marcelo Moraes , Vidal Claudio Henrique Fernandes , Moura Samuel Miranda de , Rodrigues Mateus de Sousa
Published: June 2023

Objective The objective of the present study was to assess the hormonal alterations that occurred in patients with subarachnoid hemorrhage.

Methods This is a case series with 21 patients diagnosed with subarachnoid hemorrhage of aneurysmal etiology up to 30 days after the ictus. The following hormonal measurements were performed in these patients: cortisol, GH, testosterone, prolactin, estradiol, FSH, LH, FSH, T3, T4 and free T4. The hormonal results of the cases were compared with the results of twelve volunteers from the control group and correlated with findings in brain tomography, cerebral angiography, Hunt-Hess scale, and vasospasm.

Results The main altered hormones were cortisol (52.6%), GH (42.9%) and TSH (28.6%). There was a trend towards more severe cases in the following groups of patients: Hunt-Hess scale > 2, Fisher scale > 1, aneurysmal topography in the anterior communicating artery and those who had vasospasm.

Conclusion The present study observed the tendency of pituitary hormonal changes in patients with subarachnoid hemorrhage of aneurysmal etiology, corroborating the need for dosage of hormones from the hypothalamic-pituitary axis in the management of these cases.
Mitophagy Regulation by Kangxian Yixin Granule in a Mouse Model of Dilated Cardiomyopathy
Authors: Liu Shunyu , Hei Xuanding , Wu Hong , Wang Zhentao
Published: June 2023

Objective Kangxian Yixin granule (KXYXG) has been found to be effective in the clinical treatment of dilated cardiomyopathy (DCM). We aim to explore the effect of KXYXG and the underlying mechanism in a mouse model of DCM.

Methods Thirty specific pathogen-free (SPF) male cTnTR141W mice with DCM were randomly divided into the model group, KXYXG (20.4 g/kg/d) group and coenzyme Q10 (CoQ10) (1.5 mg/kg/d) group; 10 SPF male C57BL/6J mice were included to form the normal group. The mice in KXYXG group and CoQ10 group were administered by oral gavage for 8 weeks. M-echocardiography was used to evaluate the cardiac function in mice, and hematoxylin and eosin staining and transmission electron microscopy were performed to observe morphological characters. The colocalization and expression levels of mitophagy-related proteins were observed using immunofluorescence and western blot.

Results Compared with the normal group, the model group showed ventricular remodeling, cardiac insufficiency, disordered arrangement of cardiomyocytes, as well as disordered mitochondria and irregular and diffuse swelling. Furthermore, the model group had lower mitophagy protein colocalization and autophagy flux. Furthermore, PINK1 and Parkin expression levels decreased in the mice with DCM (p < 0.05). KXYXG could decrease the left ventricular end-diastolic and end-systolic diameters and mitochondrial injury, rescue cardiac dysfunction and remodeling, and protect against myocardial ultrastructure changes in the mice with DCM. KXYXG also increased the colocalization levels of mitophagy-related proteins and PINK1 and Parkin expression levels compared with those in the model group (p < 0.05).

Conclusion KXYXG can protect against heart injury by possibly activating the PINK1/Parkin pathway and mitophagy in mice with DCM.