bluuebunny/crossref_metadata_2025 huggingface dataset:
СТРАТЕГИЧЕСКОЕ УПРАВЛЕНИЕ ФИНАНСАМИ ОРГАНИЗАЦИЙ
Authors: Сакибаев Канатбек , Нуралимова Бегимай , Нурали кызы Айкокул
Published: June 2024

В статье рассматриваются роли и значения финансовой стратегии в формировании общей стратегии организации, выявлены принципы и факторы финансовой стратегии предприятия. На основе раскрытия сущностных и организационных характеристик стратегического управления финансами, а также всесторонне учитывая финансовые возможности предприятий и объективно оценивая характер внешних и внутренних факторов, финансовая стратегия обеспечивает соответствие финансово-экономических возможностей предприятия условиям, сложившимся на рынке. Стратегия управления финансами предусматривает определение долгосрочных целей финансовой деятельности и выбор наиболее эффективных способов их достижения.
СОСТОЯНИЕ ВОДНЫХ РЕСУРСОВ И ЕЕ ЭКОНОМИЧЕСКОЕ ВЛИЯНИЕ НА ОРОШЕНИЕ СЕЛЬСКОХОЗЯЙСТВЕННЫХ ЗЕМЕЛЬ КЫРГЫЗСТАНА
Authors: Убайдуллаев Мирланбек , Кенжеева Максуда , Осмонов Жоомарт , Токтосунова Аида
Published: June 2024

В статье раскрываются актуальные проблемы состояния водных ресурсов Кыргызстана, а также ее влияние на использование сельскохозяйственных земель на современном этапе. Обосновываются проблемы использования водных ресурсов с учетом современных требований водопользователей и сложившихся реалий на практике. Выявлены причины проблем и пути их преодолений на основе установленных законов рынка. Также предлагаются конструктивные меры по решению проблем, связанных с реструктуризацией существующих и вводом в пользование новых оросительных сетей, состояние которых вызывает много вопросов и которые достаточно отрицательно сказываются на достижении конечного результата землепользователями. Особое внимание в статье уделяется проблемам государственного и иного вида финансирования как в решении проблем связанных с состоянием оросительных сетей, а также землепользователей, решение которых положительно повлияло бы на состояние сельскохозяйственной отрасли страны в целом.
RAD6 Overexpression and Ovarian Cancer Chemo-Resistance: Flow Cytometry and Immunohistochemistry
Authors:   Department of Obstetrics and Gynecology, Gynecologic-Oncology Division, Cipto Mangunkusumo Hospital, Jakarta, Indonesia., Sihombing Unedo Hence Markus
Published: June 2024

Objective: Ovarian cancer is one of the deadliest women’s cancers in the world. Nearly all the patients have poor prognosis and recurrence after standard therapy because of chemo-resistance. The standard therapy is cytoreductive debulking surgery followed by platinum-based chemotherapy. RAD6 has an important role in chemo-resistance. RAD6 is an E2 Ubiquitin-Conjugating Enzymes (UBE2) enzyme required for DNA repair, cell proliferation, and cell mutagenesis. Increased expression of RAD6 is believed to be associated with chemoresistance, recurrence, and poor prognosis of the disease. We aimed to study RAD6 relationship with ovarian cancer chemo-resistance and its ability to predict chemo-resistance. Methods: This study is an ambispective cohort study of 32 people in each group at the obstetrics-gynecology and pathology Department of Cipto Mangunkusumo, Tarakan, Dharmais, and Fatmawati Hospital. All patients will undergo standard cytoreductive debulking and histopathological examination followed by six series of chemotherapy followed by six months of observation. After the observation, we determine therapy response with the RECIST Criteria (Response Criteria in Solid Tumors). The chemo-resistance and chemo sensitive groups will be analyzed according to the therapy response. Our study is the first study examining RAD6 in ovarian cancer from flow cytometry blood test and directly from ovarian cancer tissue by double immunohistochemistry.
Local Alveolar Hemorrhage Post Dialysis Catheter Insertion: A Case Report
Authors:   Department of Pulmonary & Critical Care, Faculty of Medicine, Lebanese University, Beirut, Lebanon., Zeinab EL Mawla , Shereen Mollaei ,   Department of Pulmonary & Critical Care, Bahman Hospital, Beirut, Lebanon.
Published: June 2024

Introduction: The Internal Jugular Vein catheter (IJV) is essential in the care of hemodialysis patients. This case presents an unusual complication of localized alveolar hemorrhage following left IJV catheterization. Case presentation: 66 years old, lady, with multiple comorbidities presented with hemoptysis and dyspnea after insertion of left internal jugular vein catheter, found to have local alveolar hemorrhage and pneumothorax. Patient started on supportive management, improving and discharged home after 2 days. Conclusion: Local alveolar hemorrhage, very rare but lethal complication can occur following IJV catheterization. Experienced physicians, ultrasound usage and avoidance of force during insertion can prevent this life-threatening complication.
Insect Chemosensory Proteins against COVID-19
Authors:   Taishan Scholar, Biotechnology Research Center, Shandong Academy of Agricultural Sciences, 202 Gongye North Road, Jinan, Shandong, 250100, China., Picimbon Jean-François
Published: June 2024

This article describes a novel strategy to fight SARS-CoV-2 infection by employing tiny soluble binding proteins called “Odorant Binding Proteins” (OBPs), “Niemann-Pick Type C2 (NPC2s)”, and “Chemosensory Proteins” (CSPs). The possible interactions between these proteins and sensory receptors are not relevant to COVID-19. We concentrate on the interaction between the protein-binding site and C18 lipids in COVID. Extended lipid chains, like palmitic acid (C18), oleic acid (C18:1), and linoleic acid (C18:2) resemble the primary components of membrane viral particles. The virus’s surface is covered in C18 lipids. In light of this, OBPs’, NPC2s’ and CSPs’ capacity to interact with C18-lipids and transfer them to Degradative Enzymes (ODEs) may provide a novel molecular strategy for combating coronavirus infection, regardless of the course of viral mutation. In order to confine COVID virus variations in a hydrophobic pocket and/or produce viral particles devoid of an outer protective envelope, proteins with the ability to bind long lipid chains on viral surfaces or peplos may show great promise.
Metformin reverses the effect of high glucose on mesenteric artery relaxation in normal rats
Authors:   Graduate Studies and Research Section, School of Medicine, National Polytechnic Institute, Plan de San Luis and Díaz Mirón, Santo Tomas neighborhood, Miguel Hidalgo delegation, Mexico City, 11340, Mexico., Rojas-Martinez Raúl , Zúñiga Cruz Carlos Alberto ,   Graduate Studies and Research Section, School of Medicine, National Polytechnic Institute, Plan de San Luis and Díaz Mirón, Santo Tomas neighborhood, Miguel Hidalgo delegation, Mexico City, 11340, Mexico., Hernandez María Esther Ocharan ,   Graduate Studies and Research Section, School of Medicine, National Polytechnic Institute, Plan de San Luis and Díaz Mirón, Santo Tomas neighborhood, Miguel Hidalgo delegation, Mexico City, 11340, Mexico.
Published: June 2024

Elevated glucose produces alterations in the cardiovascular system, which affect the health of subjects with these increases, which affect systems such as the gastrointestinal, since the mesenteric arteries play an important role for the proper development of the individual. These diseases are related and cause great morbidity and mortality worldwide. Metformin is a biguanide used to control blood glucose levels. This study assessed the effect of metformin on arterial tension and endothelial function on rat normal mesenteric arteries. Arteries incubated in glucose (30 mM) demonstrated a profoundly impaired endothelium-dependent relaxation to acetylcholine. The treatment with metformin (1 mM) produced the change in the vascular activity, like the control group. These results indicated that the action of metformin in the vascular activity is recovered to normal condition, which is important in patients with diabetes mellitus type 2, already the cardiovascular alterations were presents in these patients. Glucose modified the effect of Nitric oxide synthase and CYTP450, decreasing the production of Nitric Oxide and hyperpolarizing factor, in arteries relaxed with acetylcholine, where metformin reversed to normal conditions. On the other hand, the used of metformin plus indomethacin produced inhibition on metformin, effects inducing a mayor inhibition on the vascular relaxation to acetylcholine. Also, metformin presented a minimum effect on K+ channels, when are inactivated with TEA, recovering of manner partial the action of this channel, increased relaxation effect by acetylcholine. Metformin effect is not due to osmotic control or oxidative stress. An important effect is the use of analgesics such as indomethacin, which produces dysfunction of the vascular endothelium, generating the presence of diseases due to the state of hypertension obtained in the mesenteric arteries, affecting the proper functioning of the gastrointestinal system, decreasing the uptake of nutrients and presenting various diseases.
Evaluation of multiple autoantibodies to tumor-associated antigens as potential diagnostic markers for pancreatic cancer
Authors:   Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Wang Xiao , Qiu Cuipeng ,   Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Qin Jiejie ,   Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Wang Bofei ,   Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Zhang Jian-Ying ,   Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Yu Baofa ,   Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Published: June 2024

The aim of the study is to evaluate the clinical significance of autoantibodies to GNA11, MSLN, GNAS, CEBPA, MDM2, p16, Sui1, Calnuc, PTEN in Pancreatic Cancer (PC). A total of 33 sera from PC patients and 45 sera from Normal Controls (NC) were enrolled to measure nine autoantibodies by Enzyme-Linked Immunosorbent Assay (ELISA). Multiple parameters in individual or combination forms were applied for evaluation. The level of all autoantibodies except anti-GNAS and anti-Calnuc was significantly higher in PC patients than that in normal controls. Significantly increased frequencies were found for four autoantibodies to MSLN, p16, PTEN and Sui1 at 75.8%, 66.7%, 30.3% and 27.3% compared to normal controls (4.9%). The ability of these autoantibodies to distinguish PC patients from normal controls reflected by the area under ROC curve (AUC) ranged from 0.666 to 0.884, with anti-p16 (0.884 of AUC) and anti-MSLN (0.857 of AUC) showing the strongest diagnostic performance. The combination of anti-MSLN and anti-p16 could improve the diagnostic sensitivity. In addition, two autoantibodies to MSLN and Sui1 in PC patients decreased after chemotherapy. Four autoantibodies to MSLN, p16, Sui1, PTEN showed potential diagnostic markers for pancreatic cancer, with anti-MSLN and anti-p16 in best performance. The combination of these two autoantibodies showed the most economical and practical potential. The significance of the reduction of autoantibodies to MSLN and Sui1 in PC patients who were subjected to chemotherapy needs to be further explored.
Defecation disorders in patients following definitive surgery for Hirschsprung’s disease: A tertiary care hospital study
Authors:   Department of Pediatric Surgery, Niloufer Institute for Women and Child Health, Hyderabad, Telangana, India., Manoj Kumar Posam , Rashmi Tresa Philpose ,   Department of Pathology, Osmania Medical College, Hyderabad, Telangana, India., Reddy Gowni Ashrith ,   Department of Pediatric Surgery, Niloufer Institute for Women and Child Health, Hyderabad, Telangana, India.
Published: June 2024

Background: Hirschsprung’s Disease (HD) poses a common challenge in pediatric surgery, often leading to congenital intestinal obstruction. Despite advancements in surgical techniques, postoperative Defecation Disorders (DDs) significantly impact the well-being of affected children. This study investigates the clinical manifestation, management, and outcomes of DDs in children after definitive surgery for HD, utilizing a comprehensive systematic algorithm.
INNOVATIONS IN TEACHING ENGLISH: A COMPARATIVE STUDY OF MODERN PEDAGOGICAL APPROACHES
Authors:   Kokand University, Azimov Shokhrukh
Published: June 2024

This comparative study explores the effectiveness of modern pedagogical approaches versus traditional methods in teaching English to intermediate-level learners. Specifically, it examines the impact of flipped classrooms, digital storytelling, and gamification on student engagement, comprehension, and language acquisition across a sample of 120 students from three different high schools. Utilizing both quantitative assessments, including pre-tests and post-tests, and qualitative measures such as student questionnaires and classroom observations, the study evaluates the efficacy of each teaching approach. Preliminary resultsindicate that modern approaches significantly enhance student motivation and facilitate a more practical application of the English language, surpassing traditional methods in improving oral proficiency and reading comprehension. However, traditional methods maintain a slight edge in fostering grammatical accuracy. This paper elaborates on the potential of integrating innovative teaching strategies in the English language curriculum to better engage students and prepare them for real-world language use, while suggesting the continued value of conventional techniques for foundational language instruction.
DEVELOPING LEARNER DICTIONARIES WITH CORPUS LINGUISTICS METHODS
Authors:   Alisher Navo'i named after Tashkent state university of uzbek language and literature, Niyazova Gulnorakhon
Published: June 2024

This article explores the intersection of corpus linguistics and language teaching through the lens of specialized learner dictionaries in the context of English for Specific Purposes (ESP) and English for Academic Purposes (EAP) teaching. It highlights the role of corpus lexicography in bridging theory and practice, emphasizing the practical applications of corpus analysis in constructing learner dictionaries tailored to the needs of ESP/EAP students. Drawing on insights from corpus studies and practical research, the article discusses the challenges and opportunities in developing specialized dictionaries that facilitate language learning and teaching. By examining the relationship between theory and tools in lexicography, it advocates for greater collaboration between researchers, educators, and lexicographers to enhance language education through innovative dictionary construction methods.
DEVELOPMENT OF THE ENGLISH LESSON IN NEW METHODICAL METHODS
Authors:   Tashkent University of Information Technology, Nigmatova Khilola
Published: June 2024

This study investigates the effectiveness of using new (methodical methods) in teaching English as a foreign language. The study compares the use of traditional with the use of new, such as project-based learning, inquiry-based learning, cooperative learning, gamification, and blended learning. The results of the study show that the use of new methodical methods leads to significant improvements in student motivation, engagement, and communicative competence.
METHODS AND TECHNIQUES FOR ENRICHING VOCABULARY IN JUNIOR SCHOOLCHILDREN IN RUSSIAN LANGUAGE LESSONS
Authors:   Alisher Navo'i named after Tashkent state university of uzbek language and literature, Turdiyeva Ro'za , Xabibullayeva Marvarid ,   Faculty of Theoriy And practice of translation inUniversity. A.Navoiy
Published: June 2024

The article is devoted to the problem of the formation of literary concepts in elementary school
GAMIFICATION IN DISTANCE LANGUAGE LEARNING IN ESP
Authors:   Tashkent State Law University, Usmonova Oyshajon
Published: June 2024

This article explores the application of gamification in distance language learning for law students at Tashkent state university of law who have intermediate and advanced levels of English proficiency. It investigates how game-based learning techniques can enhance the experience and effectiveness of English for Specific Purposes (ESP) in the legal field. By examining various gamification methods and their impact on learning outcomes, this study aims to shed light on the benefits and challenges of integrating gamification in virtual legal language courses. Results demonstrate the potential of gamified learning in improving students' engagement, motivation, and overall language skills.
TECHNIQUES FOR ASSESSING THE PERFORMANCE OF ESL STUDENTS
Authors:   Alisher Navo'i named after Tashkent state university of uzbek language and literature, Turdieva Roza
Published: June 2024

The article focuses on different types of assessment and its using both in higher and secondary education system. Assessment is a crucial part of the teaching process because it allows us to determine where our students are in the learning process, how successful our instructional tactics have been, and whether or not there are any additional problems that we need to be aware of as we plan future lessons and student support. Assessment as learning, assessment of learning and assessment for learning as tools are described in the article as well.
IMPORTANCE OF IMPLEMENTING INNOVATIVE TECHNOLOGIES INTEACHING READING AND WRITING
Authors:   Alisher Navo'i named after Tashkent state university of uzbek language and literature, Mirzayeva Nasiba
Published: June 2024

The article examines the main aspects of the connection between reading and writing, as well astheir inextricable complement to each other, as a tool for correct development speech. The article also discusses the innovative experience of world experts in the field of this area, supported by various relevant methods and techniques that can diversify the information content of each lesson.
GEOSPATIAL TECHNIQUES AIDED SPATIAL GROUNDWATER QUALITY ASSESSMENT FOR DRINKING PURPOSE IN CHARKHI DADRI DISTRICT, HARYANA
Authors: Kumar Anup , Himanshu  , Kumar Satish
Published: June 2024

Water is important for living beings for drinking and other domestic uses. Good quality water plays vital role in establishment of human health, settlements, agriculture and industrial growth. Good quality groundwater is important mainly for drinking purpose because polluted drinking water can cause many health problems. Geospatial techniques including remote sensing satellite data, geographical information system (GIS) and global positioning system (GPS) are playing vital role in assessment of groundwater quality. In the present study spatial groundwater quality has been assessed for drinking purpose in Charkhi Dadri district of Haryana. Charkhi Dadri district is located between latitudes 28.385446 N to 28.814909 N and longitudes 75.815527 E to 2 76.466172 E and covers 1377 km . In the study area forty three groundwater samples were collected in 250 ml double capped plastic bottles. Groundwater samples were analyzed using Field Water Testing Kit prepared by Tamil Nadu Water Supply and Drainage (TWAD) Board, Chennai for twelve chemical parameters i.e. pH, alkalinity, hardness, chloride, total dissolved solids, fluoride, iron, ammonia, nitrite, nitrate, phosphate and residual chlorine. Point chemical data were converted into spatial form in ArcGIS 10.4.1 software using inverse distance weighted (IDW) interpolation technique. The interpolated groundwater quality data were categorized in three classes i.e. desirable, permissible and non-potable as per BIS (IS 10500:2012) drinking water standards and calculated the area of each drinking water class for each chemical parameter. The spatial distribution of 2 chemical parameters in the study area shows that pH, nitrite, phosphate, residual chlorine cover 1377 km area 2 2 2 under desirable, alkalinity covers 3 km area under desirable, 1371 km area under permissible and 3 km area 2 2 2 under non-potable, hardness covers 209 km area under desirable, 992 km area under permissible and 176 km 2 2 area under non-potable, chloride covers 448 km area under desirable, 863 km area under permissible and 26 2 2 2 km area under non-potable, TDS covers 1239 km area under permissible and 138 km area under non2 2 2 potable, fluoride covers 119 km area under desirable, 401 km area under permissible and 857 km area under 2 2 non-potable, iron covers 1205 km area under desirable and 172 km area under non-potable, ammonia covers 2 2 2 954 km area under desirable and 423 km area under non-potable, nitrate covers 1377 km area under nonpotable. The study is highly useful for drinking water supply department as well as local users for searching good quality drinking water sites in the study area.
Contaminação microscópica por matérias estranhas em noz-moscada, cúrcuma, gengibre, colorífico, pimenta-do-reino e páprica comercializados no estado de São Paulo, Brasil. (Parte I)
Authors: Prado Sonia de Paula Toledo , Rodrigues Matheus Leandro , Aquino Cinthia Iara de , Iha Maria Helena
Published: June 2024

O objetivo deste trabalho foi avaliar a presença de matérias estranhas em noz-moscada, (Myristica fragrans Houttuyn), cúrcuma (Curcuma longa Linnaeus), gengibre (Zingiber officinale Roscoe), colorífico (mistura de urucum [Bixa orellana Linnaeus] com fubá), pimenta-do-reino (Piper nigrum Linnaeus) e páprica (Capsicum annuum  Linnaeus) conforme a legislação sanitária. Foram analisadas 180 amostras empregando os métodos preconizados pela AOAC International, de maio de 2018 a maio de 2020. A presença de ao menos uma matéria estranha foi observada em 80% das amostras. Pelos animais foram observados em todos os produtos e fragmentos de insetos foram encontrados na maioria das amostras. Ácaro, inseto inteiro, larva de inseto, bárbula e exúvia também foram encontrados, além de fibras sintéticas e fragmentos de microplásticos. Quanto à legislação, 47,8% das amostras estavam acima dos limites de tolerância, destas, 90,7% por conterem matérias estranhas indicativas de falhas na aplicação das boas práticas e 9,3% por matérias estranhas indicativas de risco à saúde. Os resultados obtidos denotam ineficiência da aplicação das medidas de boas práticas na cadeia produtiva e alertam para a intensificação da fiscalização direcionada ao cumprimento das normas sanitárias, além de provocarem a reflexão sobre a necessidade de alterações na legislação referente às matérias estranhas.
Análise da adequação do termo detox nos rótulos de bebidas industrializadas à base de frutas e vegetais
Authors: Prates Sarah Morais Senna , Nespolo Juliana Sampaio , Sabion Natália Adan , Alves Luciene , Anastácio Lucilene Rezende
Published: June 2024

Dietas populares, como as detox, surgem a todo o momento. Todavia, poucos dados científicos comprovam a eficácia e segurança destas dietas. Este trabalho avaliou rótulos de bebidas à base de frutas e vegetais e identificou as que se autodenominam detox. Tratou-se de estudo transversal descritivo, realizado de setembro a outubro/2016. O tamanho da porção na informação nutricional e as alegações encontradas nos rótulos foram analisados em relação às legislações vigentes.Composição nutricional, quantidade total de ingredientes e presença de aditivos alimentares e/ou outros ingredientes não usuais em preparações culinárias foram comparados entre as bebidas detox e as comuns. De 83 produtos analisados, 9,6% (n=8) se autodenominaram detox. A composição nutricional e o número médio de ingredientes não diferiram entre as bebidas detox e as comuns. Alegações nutricionais e de saúde estavam presentes em 77,1% (n=64) dos produtos e 53,0% (n=44) apresentaram alegações não previstas na RDC nº 54/2012. As informações mais frequentes foram quanto aos teores de micronutrientes, açúcares, sódio e fibras. O termo detox, apesar de não permitido, é encontrado neste tipo de produto no mercado brasileiro. Os resultados sugerem que o termo detox seja utilizado mais como estratégia de marketing do que como real alegação de propriedade nutricional.
Lipídios e ácidos graxos em fórmula infantil: comparação de metodologias de extração convencional x direta
Authors: Kus-Yamashita Mahyara Markievicz Mancio , Aued-Pimentel Sabria , Mancini-Filho Jorge
Published: June 2024

Os lipídios em alimentos são analisados, de forma convencional, em duas etapas: extração com solvente orgânico ereação de esterificação da gordura, neste caso o tipo de gordura de cada alimento influencia na escolha dos reagentes da extração e esterificação. No método direto, estes procedimentos são realizados em uma etapa única. Este trabalho comparou a metodologia convencional de extração e quantificação de lipídios e ácidos graxos, com um método direto em fórmula infantil. Foi utilizada uma amostra de referência de fórmula infantil com valores certificados para lipídios e ácidos graxos da Nacional Institute of Standards and Technology. A metodologia convencional para a análise de lipídios empregou método com hidrólise ácida; para a determinação dos ácidos graxos, a gordura foi extraída com uma mistura de éter etílico e éter de petróleo. O método direto fundamentou-se na transesterificação direta com metóxido de sódio. Na análise dos ácidos graxos, a maioria dos resultados demonstrou valores estatisticamente iguais (α < 0,05) para os dois métodos. O método direto demonstrou ser apropriado, principalmente pela diminuição do tempo de análise e quantidade de solventes.
Avaliação das rotulagens de alimentos frente à legislação vigente e do uso de alegações não regulamentadas
Authors: Guimarães Valdeir de Oliveira , Lima Hatanne Carla Fialho Moraes , Moraes Allan Robledo Fialho
Published: June 2024

Este estudo objetivou analisar a conformidade de 56 rótulos de produtos alimentícios divididos em 14 categorias em relação às legislações gerais e específicas de rotulagem de alimentos vigentes até o momento de sua publicação, bem como apresentar abordagens com relação à necessidade da constante melhoria e aperfeiçoamento da legislação. Constatou-se um total de 158 não conformidades e que 55,3% dos produtos avaliados apresentavam pelo menos uma não conformidade em sua rotulagem. Biscoitos e produtos artesanais foram as categorias que mais apresentaram rótulos com pelo menos uma não conformidade. Entre as informações obrigatórias, as referentes ao lote, à data de fabricação, ao prazo de validade e à conservação foram as mais recorrentes entre as não conformidades. Verificou-se também que algumas expressões como “produto caseiro”, “vegano”, “vegetariano”, “base vegetal”, entre outras, requerem melhor regulamentação ou legislação específica, portanto, não puderam ser avaliadas em relação à conformidade. Os motivos para tal cenário podem ser a aplicação incorreta da legislação e o uso de estratégias de marketing com o objetivo de atender a desejos e expectativas dos consumidores. Portanto, faz-se necessária uma intensificação da fiscalização, assim como maior celeridade na regulamentação de alegações específicas por parte dos órgãos responsáveis.
O consumo de substitutos de origem vegetal é nutricionalmente mais vantajoso que os produtos cárneos?
Authors: Christ Rosana Ribeiro , Vasconcelos Christiane Mileib
Published: June 2024

A busca por um padrão alimentar mais saudável, bem como fatores éticos e de sustentabilidade relacionados ao consumo de carne, vem fazendo com que a cada dia mais pessoas se tornem adeptas a dietas à base de plantas. Concomitantemente, com o aumento de adeptos a essas dietas, vem crescendo nos países ocidentais a oferta de alimentos industrializados de base vegetal, que tem como objetivo substituir os produtos cárneos. O presente estudo comparou os rótulos de produtos de origem animal (POA) e seus análogos de origem vegetais (POV) comercializados nas principais redes de supermercados da grande Vitória, Espírito Santo, e avaliou a contribuição nutricional deles ao consumidor. Foram avaliadas 80 embalagens de produtos, sendo 42 de POA e 38 POV. POV, quando comparados aos POA, não apresentaram diferenças (p>0,05) quanto ao valor calórico, proteínas, gordura total, gordura saturada e sódio. Se sobressaindo apenas no maior teor de carboidratos e fibras e em não possuir gorduras trans em sua composição. Assim, conclui-se que, os POV possuem equivalência em alguns dos constituintes nutricionais analisados. Por isso, se não há restrições para o consumidor, seja por questões de saúde, cultura ou hábito, a substituição de POA por POV não se faz nutricionalmente tão superior.
Optimization Strategies for Deep Learning Models in Natural Language Processing
Authors: Yao Jerry , Yuan Bin
Published: June 2024

Deep learning models have achieved remarkable performance in the field of natural language processing (NLP), but they still face many challenges in practical applications, such as data heterogeneity and complexity, the black-box nature of models, and difficulties in transfer learning across multilingual and cross-domain scenarios. In this paper, corresponding improvement measures are proposed from four perspectives: model structure, loss functions, regularization methods, and optimization strategies, to address these issues. Extensive experiments on three tasks including text classification, named entity recognition, and reading comprehension confirm the feasibility and effectiveness of the proposed optimization solutions. The experimental results demonstrate that introducing innovative mechanisms like Multi-Head Attention and Focal Loss, and judiciously applying techniques such as LayerNorm and AdamW, can significantly improve model performance. Finally, this paper also explores model compression techniques, providing new insights for deploying deep models in resource-constrained scenarios.
Analysis of cyclical systemic risks in spain and of their mitigation through countercyclical bank capital requirements
Authors: Estrada Ángel , Pérez Montes Carlos , Abad Jorge , Broto Carmen , Cáceres Esther , Ferrer Alejandro , Abad Jorge , Ganics Gergely , García Villasur Javier , Hurtado Samuel , Lavín Nadia , Marbet Joël , Martorell Enric , Martínez-Miera David , Molina Ana , Pablos Irene , Pérez-Quirós Gabriel
Published: June 2024

This paper first identifies the level of cyclical systemic risks in Spain, also calibrating their impact on the solvency of the banking system, and, second, assesses the costs and benefits of the countercyclical use of capital requirements. The first part of the paper is based on an integrated analysis of indicators and other quantitative and qualitative information, while impacts are calibrated using a combination of macroeconomic projection models and stress tests. The second part of the analysis is undertaken using quantile regression models, applied to European data, Bayesian time series models, applied to data for Spain, and a general equilibrium model. The integrated analysis to identify cyclical systemic risks shows the importance of a holistic approach monitoring the different dimensions of these risks, while the impact calibration shows that slight or intermediate materialisation of such risks also involves material capital consumption for the banking sector. The different methodologies applied for cost-benefit analysis find favourable results, in terms of GDP and credit growth, for the activation of releasable capital requirements in situations where cyclical systemic risks are intermediate and high and, notably, for their release in adverse cyclical phases.
Viajeros e inmigrantes aficionados a Wagner como mediadores culturales entre Alemania y Argentina: traducciones, libros y revistas a inicios del siglo XX
Authors: Irurzun María Josefina
Published: June 2024

En este artículo nos proponemos examinar las formas en que el “viaje musical” a Europa posibilitó el tránsito y la formación de saberes entre Argentina y Alemania, a partir del soporte físico del libro “en movimiento” como de las prácticas vinculadas a la cultura impresa y la traducción, en la Buenos Aires de principios del siglo XX. Se comparan de manera exploratoria, tres modalidades diferentes de circulación y lectura de libros impresos sobre la obra de Wagner, habilitadas por el viaje a Bayreuth, meca del “culto wagneriano”. En primer lugar, consideramos la narración personal que sigue la tradición de las guías turísticas en circulación durante el siglo XIX, a partir del caso de Miguel Cané (h). En segundo lugar, el impacto del acceso de primera mano a la obra completa del filósofo alemán Friedrich Nietzsche, por parte del crítico musical Mariano Barrenechea, en la coyuntura previa y posterior a la Primera Guerra Mundial. Por último, el trabajo interpretativo realizado por Josep Lleonart Nart –referente de la colectividad inmigrante catalana porteña- desde su pertenencia a un conjunto transnacional de críticos y aficionados catalanes cuya travesía hacia la “colina verde” había servido de insumo para traducir las características dramáticas del arte wagneriano.
THE INFLUENCE OF TRADITIONS AND REVOLUTIONARY AESTHETICS OF THE ERA OF HISTORICAL TURNING POINT ON THE FORMATION OF LITERATURE (BASED ON THE ART OF THE WORD OF ADYGHE LITERATURE)
Authors: Ашинова Ю.А. , Соколова Г.В.
Published: June 2024

Рассматривается процесс формирования отечественной литературы 20 – 30-х годов ХХ-го века. Актуализируются вопросы влияния традиций фольклора, про-светительства, опыта русского искусства слова, а также идеологии и эстетики эпохи исто-рического перелома на творчество писателей. Выявляются особенности становления в этих условиях новописьменных литератур. Подвергается анализу воздействие на станов-ление художественного процесса нового образца такого важнейшего фактора как много-национальная общность, что позволяет включить литературы в общероссийское художе-ственно-эстетическое единство.

The study examines the development of Russian literature during the 1920s and 1930s. It explores the impact of folklore traditions, enlightenment, Russian verbal art, as well as the ideology and aesthetics of the era on the work of writers. The features of the formation of newly written literature in these conditions are revealed. The study analyses the influence on the formation of the artistic process of a new sample of such an important factor as a multinational community, which makes it possible to include literature in the all-Russian artistic and aesthetic unity.
Sustainable methods for growing turmeric: Evaluating the effects of synthetic and organic fertilizers on vegetative and reproductive attributes
Authors: Sunuwar Chandani , Koirala Soniya , Acharya Ravi , Chaudhary Nishu , Bhandari Uma Devi , Rai Melina , Niraula Supriya , Mehta Rupesh Kumar
Published: June 2024

This study aimed to assess the influence of various biofertilizer sources on turmeric (Curcuma longa L.) cultivation in Eastern Nepal. The research was conducted at G.P Koirala College of Agriculture and Research Centre, Sundarharaicha, Morang, Nepal, from April 2023 to January 2024. The experiment utilized a randomized complete block design (RCBD) with seven treatments including T1: Recommended dose (RD) of NPK, T2: Goat manure (GM), T3: Organic manure (OM), T4: Poultry manure (PM), T5: Vermicompost (VC), T6: Farmyard manure (FYM), T7: Control, replicated three times. Turmeric cultivation practices were implemented following standard agronomic procedures. The recommended dose of synthetic fertilizer, NPK, exhibited the highest enhancement across multiple vegetative and reproductive growth parameters of turmeric, with notable increases in plant height, leaf number, tillers per plant, primary and secondary fingers per clump, fresh rhizome yield, dry yield, and dry recovery percentage. Among the organic sources, goat manure and poultry manure also showed promising results in enhancing turmeric yield and quality. Specifically, NPK recorded the highest fresh rhizome yield at 21.30 tons ha-1, while goat manure and poultry manure yielded 20.35 tons ha-1 and 18.69 tons ha-1, respectively. In contrast, the lowest fresh rhizome yield was observed in the control group, indicating minimal enhancement in yield without fertilizer supplementation. The results highlight how organic farming methods may be a good substitute for traditional chemical fertilizers in the context of sustainable turmeric production.
Ўзбек Ва Турк Тилларида Замоннинг Муқаддас Қадрият Сифатида Ифодаланиши Хусусида
Authors: Yıldız Çetin , Sultonova Muxammadjanovna Shoxista
Published: June 2024

Вақт инсон учун ҳаётни тартибга солиш, баҳолаш ва оргатиш каби коп жиҳатдан энг қимматли тушунчалардан биридир. Ҳам диний, ҳам ижтимоий, ҳам маданий ҳаётда муҳим орин тутган бу тушунча бугунги кунда коплаб илмий соҳаларда тадқиқот мавзусидир. Ана шундай фан соҳаларидан бири тилшуносликдир. Тилшуносликнинг тавсифий, қиёсий ва маданий лингвистик таҳлил усуллари билан муқаддас матнлардаги вақт тушунчаси, вақтнинг инсон ҳаётини қуршаб турган омил эканлиги ва унинг турли тил воситаларида, базан муқаддас, базан оддий ифодалар билан қолланилиши, вақт билан боглиқ диний амрларнинг халқ тилига чуқур сингиб бориш масаласи котарилгандир. Вақтни ифодаловчи созларнинг муқаддаслиги ҳам вақтнинг муқаддаслиги билан боглиқ. Бу ҳолат муқаддас матнларда тез-тез учраб туради ва бугунги кунда ҳам, айниқса, мақол ва иборалар каби тургун бирикмаларда козга ташланади. Астрологик ва эсхатологик диний тушунчаларни конкретлаштириш, инсон учун муҳим болган давр ва вақтларни қайд этиш билан бирга халқ тақвимида турли маросимлар (байрам ва иш кунлари, роза вақти, яхши ва ёмон кунлар кабилар) пайдо болган. Бу маросимлар вақт билан боглиқ қолиплашган соз ва ифодаларни оз ичига олади. Генетик томондан қардош ҳисобланган турк ва озбек халқлари ортасида тил ва маданият жиҳатидан бирмунча фарқлар мавжуд болса-да, бу икки жамиятнинг вақт тушунчасига болган қарашлари этиқод бирлиги туфайли охшашдир. Озбек ва турк жамиятлари муштарак маданиятида диний этиқодлар доирасида шаклланган вақт тушунчаси ушбу тадқиқотнинг асосий мавзусидир. Мақол, ибора ва халқ этиқодидаги вақт тушунчаси қиёсий муҳокама қилинди. Шундай қилиб, мақоламизда ҳар икки жамиятда бу тушунчанинг охшаш ва фарқли томонлари очиб берилади.
Infodemiology as a Powerful Tool in Public Health: Bridging the Digital Divide for Better Well-being
Authors: Zhao Channa , Musonye Harry Asena , Wang Peng , Pan Haifeng
Published: June 2024

Infodemiology, an emerging interdisciplinary field situated at the confluence of information science and epidemiology, has experienced significant growth in recent times. Playing a crucial role in epidemiological surveillance, infodemiology provides a supplementary perspective to conventional data sources. By monitoring variations in search volume over time, infodemiology researchers can discern shifts in public attention, emotions, or awareness pertaining to diverse health issues. This enables the timely detection of potential epidemics, emerging health concerns, or alterations in public consciousness, facilitating a more proactive approach to public health responses. Several tools, particularly Google Trends, are integral to the functioning of Infodemiology. Leveraging internet search intent, Google Trends can map population-wide public interest, utilizing extensive data sets across temporal and spatial dimensions to infer trends in disease prevalence. This paper presents a review of the diverse applications of Infodemiology in modern public health disease surveillance, highlighting the utility of Google Trends as a powerful tool within the Infodemiology framework. Advantages and limitations of Infodemiology are also examined. Through this review, we aim to elucidate the transformative potential of Infodemiology in bridging the digital divide for improved well-being.
Exercise capacity in COVID-19 surviving patients: impact of physical rehabilitation
Authors: Vieira Luana dos Passos , Martin Elisabete Antunes San , Eich Sophia Luiza , Prestes Cecilia Vieira , Dias Luiza Scheffer , Hall Grenita , Silva Andrea Lucia Gonçalves da
Published: June 2024

Background: At least 65 million individuals worldwide have Long COVID and despite efforts to explain the effects of exercise prescription on the recovery of these individuals, there is a need to explore its effects on exercise tolerance and cardiorespiratory fitness. Therefore, our main objective was to evaluate the effect of the Physical Rehabilitation Program (PRP) on muscle strength and physical exercise capacity of COVID-19 survivors. Methods: The cohort included 28 patients post COVID-19, each participant performed a comprehensive and multisystem evaluation in two visits, in the pre- and post-PRP: 1st visit = clinical evaluation periods (maximal inspiratory pressure (MIP); maximal expiratory pressure (MEP) and Duke Activity Status Index (VO2peak). 2nd visit= physical evaluation [6-minute Step Test (6MST) and Handgrip Strength (HGS)]. The PRP consisted of breathing exercises, muscle strength exercises for upper and lower limbs and aerobic exercise, 2 or 3 times/week for 03 months. Results:  The post-PRP we found: improvement in peripheral  [95%CI 2.7 (2.0-3.4), p=0.001, Huge] and respiratory [MIP 95%CI  1.6 (0.9-2.3), p<0.001, Very large) and MEP 95%CI 2.7 (2.0-3.4), p=0.001, Huge)] muscle strength; increase in cardiorespiratory fitness according to estimated-VO2peak [95%CI 2.3 (1.5-3.1), p<0.001, Huge] and the number of steps climbed in the 6MST [95%CI 1.6 (0.9-2.3), p<0.001, Very large]; adaptations resulting lower resting heart rate (HR), higher peak HR, good modulation of HR resulting from stress caused by 6MST; linear and positive association between peripheral and respiratory muscle strength and the number of steps climbed 6MST and greater HR recovery especially post-PRP; recovery-first minute HR remained unchanged post-PRP. Conclusion: In patients post COVID19, we emphasize the great effect of individualized and supervised PRP on the increase in peripheral and respiratory muscle strength/ quality and cardiorespiratory fitness. Despite the gains obtained in PRP, the risk of death based on HR recovery did not change.
Compreendendo o desempenho escolar em Goiás: Ideb e IdeGES em foco
Authors: Lima Emanuel Felipe Ramos de , Lopes José Eduardo Ferreira , Gandolfi Peterson Elizandro , Paulo Alex Fabianne de
Published: June 2024

Este artigo avalia o desempenho educacional de Goiás entre os anos de 2017 e 2021, com foco no Índice de Desenvolvimento da Educação Básica (Ideb) e no Índice de Desempenho da Gestão Descentralizada do Programa Dinheiro Direto na Escola (IdeGES-PDDE). Valendo-se de uma abordagem quantitativa de natureza descritiva, objetiva-se examinar as características das escolas goianas no IdeGES e no Ideb e a relevância dessas métricas como mecanismos para monitorar e promover melhorias na qualidade da educação. A base de dados utilizada na investigação foi construída por intermédio da plataforma Olinda, uma aplicação desenvolvida pelo Banco Central do Brasil que permite o compartilhamento de dados de várias instituições nacionais de forma rápida e descomplicada por meio da Internet. A abordagem empregada para o processamento dos dados obtidos baseou-se no Processo Padrão Inter-Indústrias para Mineração de Dados (CRISP-DM), dando origem a um método iterativo com 5 fases distintas: entendimento, preparação, modelagem, avaliação e implementação. Inicialmente, foram realizadas análises descritivas para resumir e elucidar os dados, seguidas pelo uso de correlação de Spearman com o propósito de identificar relações entre variáveis. Os resultados destacam uma correlação estatística baixa entre IdeGES e Ideb, IdeGES e variáveis ligadas a gestão escolar, Ideb e variáveis relacionadas a infraestrutura de ensino, e uma associação moderada entre recursos recebidos pelo Programa Dinheiro Direto na Escola (PDDE) e desempenho no IdeGES. As conclusões realçam que as desigualdades educacionais tendem a refletir as desigualdades socioeconômicas e que investir nas capacidades técnicas dos gestores pode não ser o suficiente em termos de PDDE, devendo ser considerada também uma mudança na distribuição de recursos. Enfim, se constata que as métricas tradicionais para avaliação da educação básica possuem limitações e, por isso, não capturam integralmente a complexidade do sistema educacional.
Pengaruh Perlakuan Panas Quenching terhadap Ketangguhan Impak pada Paduan Aluminium AC7A
Authors: Gunawan Sigit
Published: June 2024

Aluminium merupakan logam kedua terbesar yang digunakan oleh industri komponen setelah baja. Karena luasnya penggunaan aluminium, maka dibutuhkan suatu karakteristik yang berbeda-beda sesuai penggunaannya. Oleh karena itu diperlukan sebuah proses untuk meningkatkan sifat mekanis aluminium. Sifat mekanis aluminium dapat ditingkatkan melalui proses perlakuan panas. Penelitian ini bertujuan untuk menyelidiki pengaruh perlakuan panas quenching terhadap ketangguhan impak pada paduan aluminium AC7A. Variabel penelitian adalah suhu quenching. Variasi suhu quenching 250°C, 300°C, 350°C, 400°C, dan 450°C. Penelitian ini menggunakan metode eksperimen melalui pengujian laboratorium dengan menggunakan proses quenching. Paduan aluminium kemudian dibuat spesimen untuk uji kekerasan, uji ketangguhan impak dan uji struktur mikro. Spesimen dibuat dalam dua kondisi yaitu kondisi raw material dan kondisi dengan perlakuan panas quenching. Proses perlakuan panas quenching dilakukan dengan cara memanaskan spesimen pada suhu 250°C, 300°C, 350°C, 400°C, dan 450°C dengan waktu tahan selama 1 jam, dilanjutkan dengan mencelupkan ke dalam media pendingin air sampai suhu kamar. Tahap selanjutnya dilakukan pengujian kekerasan, ketangguhan impak dan struktur mikro. Hasil penelitian menunjukkan bahwa kenaikan suhu quenching menyebabkan kekerasan menurun dan ketangguhan impak cenderung meningkat. Kekerasan rata-rata tertinggi diperoleh pada suhu quenching 250°C yaitu sebesar 38,667 kg/mm2 dan nilai ketangguhan impak tertinggi diperoleh pada suhu quenching 450°C sebesar 1,479 J/mm2. Semakin tinggi suhu quenching struktur Al-Mg mulai hilang dan terlihat unsur Mg menggumpal yang menyebabkan kekerasan menurun dan ketangguhan impak meningkat.
Klasifikasi Data Penerima Beasiswa Menggunakan Algoritma C4.5
Authors: Lobo Murry Albert Agustin , Talakua Alfrian Carmen
Published: June 2024

Beasiswa merupakan salah satu sumber pembiayaan studi yang diminati oleh banyak orang. Salah bentuk beasiswa yang diminati di lingkup Universitas Kristen Wira Wacana Sumba (Unkriswina Sumba) adalah Beasiswa Bantuan Terprogram (Banter) yang bersumber dari pendanaan internal perguruan tinggi. Tinggi animo pendaftar serta banyak variable yang perlu dipertimbangkan dalam menentukan penerima beasiswa sehingga berdampak pada lamanya waktu untuk menyeleksi penerima beasiswa. Penelitian ini bertujuan untuk mengklasifikasikan data Beasiswa Banter agar dapat mengekstraksi informasi mengenai pola data dalam bentuk pohon keputusan (decision tree). Penelitian ini menggunakan algoritma C4.5 dalam membantu membuat pohon keputusan. Algoritma C4.5 sangat membantu dalam merumuskan pohon keputusan. Hasil dari penelitian ini menunjukkan bahwa lama berkuliah atau jumlah semester merupakan faktor yang sangat menentukan peluang menerima beasiswa Banter. Variabel lainnya seperti Status Orang Tua, Jumlah anggota dalam KK, Pekerjaan Ibu, Angkatan, dan Program Studi menjadi faktor turunan dalam menentukan peluang menerima beasiswa Banter.