bluuebunny/crossref_metadata_2025 huggingface dataset:
PAPILLARY CARCINOMA OF THE THYROGLOSSAL DUCT CYST: A CASE REPORT
Authors: Duzhiy Ihor , Kononenko Mykola , Moskalenko Yuliia , Zhukova Kseniia
Published: June 2023

Introduction. Thyroglossal duct cysts (TGDCs) can be diagnosed at any age. They are most common in women aged 30–40. Cysts can become malignant in 1% of patients. As a result, a very rare tumor – TGDC carcinoma ¬– develops. Some oncologists believe it is sufficient to perform surgery using the Sistrunk procedure. Other scientists insist on performing the Sistrunk procedure followed by thyroidectomy, lymph node dissection, and radioactive iodine ablation. In this report, we would like to share our successful experience in treating a patient with papillary carcinoma of PCOS.
Case report. A 47-year-old woman had persistent midline neck swelling for three years. This lesion was completely asymptomatic. The patient had no cases of head and neck irradiation or a family history of thyroid gland diseases. Physical examination revealed a solid, movable, smooth mass measuring 6.0 × 5.0 × 4.0 cm on the anterior surface of the neck. The thyroid gland was of normal size, without nodules. Lymph nodes of the neck were not enlargement. During sticking out the tongue and swallowing, the tumor moved upwards. Neck ultrasound, CT scan, and fine-needle aspiration biopsy confirmed the presence of TGDC papillary carcinoma. All laboratory results, including thyroid hormones, were within normal ranges.
The patient underwent the Sistrunk procedure, total thyroidectomy with central lymph node dissection, radioactive iodine ablation, and suppression of thyroid function with levothyroxine. The patient's follow-up period has been currently 110 months. There were no signs of relapse.
Discussion. The etiology of the malignant transformation of the TGDC remains unknown. One of the main theories is the spontaneous development of ectopic thyroid tissue located in the cyst walls. Ultrasound, CT, and MRI are considered sufficiently informative methods. A fine-needle aspiration biopsy confirms TGDC carcinoma in 53% of patients before surgery. Virtually all patients with TGDC carcinomas undergo the Sistrunk procedure. In addition, some of them perform a total thyroidectomy. Criteria for total thyroidectomy are age older than 45 years, history of neck irradiation, tumor size greater than 4 cm, presence of regional metastases, and thyroid gland dysfunction. Postoperative radioiodine ablation and suppressive levothyroxine therapy are considered the best treatment before the start of the follow-up period.
Conclusions. The treatment of patients with TGDC carcinomas should be personalized. Determining criteria should be the patient's age, gender, condition of the thyroid gland and regional lymph nodes, size of the primary tumor, resection margins, invasion of the tumor into the surrounding tissues, and family history of thyroid diseases.
REASONS FOR THE DEVELOPMENT OF INFLAMMATORY COMPLICATIONS IN INTRAUTERINE DEVICE CARRIERS
Authors: Sukharev Anatoly , Kopytsia Tetiana , Boyko Volodymyr
Published: June 2023

Introduction. In the context of the deteriorating demographic situation in the country, the decline in the living standards of the majority of the population, the deterioration of their reproductive health, and family planning issues deserve special attention [1, 2, 9]. One of the methods of contraception, which is widely used by women of reproductive age, is intrauterine contraception [7, 8]. Worldwide, millions of women have been using the IUCD for over three decades as a highly effective, safe, and convenient form of contraception [4, 5]. However, in recent years, there has been a sharp increase in the number of complications associated with this method of contraception, the most dangerous of which, both at the time of administration and due to long-term consequences for the reproductive system of women, are inflammatory diseases [6, 10].
The aim of our study was to identify the risk factors for inflammatory complications in IUCD carriers.
Methods. The study was conducted on the basis of the Municipal Non-Profit Institution "Clinical Perinatal Center of the Blessed Virgin Mary" in 2015–2021 years. In order to analyze the causes of the inflammatory complications in IUCD carriers, we examined 101 patients hospitalized at a specialized gynecological hospital for acute inflammatory processes of the uterus and appendages.
Results. The control group consisted of 20 women who were carriers of the IUCD, registered in the dispensary in the city antenatal clinic. The average age of women was 22.2 years: from 19 to 45 years. The duration of IUCD usage ranged from 8 months to 6 years. The reason for hospitalization was pain in 98% of cases, fever in 92%, violation of the ovarian-menstrual cycle in 45%, a combination of symptoms and complaints in 96% of cases. In the hospital, the standard clinical, laboratory, immunological, and ultrasound examinations were repeatedly carried out. The causative agents of inflammatory diseases of the genitals were determined using bacteriological and PCR research methods.
We revealed the association between the incidence of purulent-septic complications and the frequency of examinations performed before the introduction of the IUCD. Consequently, only 48 (59.4%) patients underwent a full clinical and laboratory examination; in the future, only 26 (25.7%) of the admitted patients were constantly observed in the antenatal clinic. Moreover, an analysis was made of the dependence between IUCD type, the duration of carriage, and the prevalence of inflammatory diseases of the female genital organs.
Conclusions. Thus, there is reason to assume that the use of IUCDs, especially Copper Y Cu 380 for more than three years, in women of childbearing age is a risk factor for the occurrence of purulent-septic complications.
IMMUNOHISTOCHEMICAL STUDY OF M1 AND M2 MACROPHAGES IN BREAST CANCER WITH MICROCALCIFICATIONS
Authors: Kolomiiets Olena , Moskalenko Roman
Published: June 2023

Introduction. Breast cancer (BC) is a significant medical and social problem, as it is the leading cause of cancer-related mortality in women worldwide. Microcalcifications in the breast tissue are essential in developing the pathological process and affect the prognosis and metastasis. The tumor microenvironment consists of cancer cells and stromal cells such as fibroblasts, endothelial cells, pericytes, and immune cells, including M1 and M2 macrophages.
The work aims to study the influence of microcalcifications on the polarization of macrophages in the tumor microenvironment of BC.
Materials and methods. The study was conducted on 60 samples of BC, divided into 30 samples of BC with microcalcifications (group I) and a control group of 30 samples of BC without calcifications (group II). All microcalcifications met the criterion of size up to ≤1 mm. To study the pathohistological changes, BC's tissue was analyzed using macroscopic description, histology, and immunohistochemical study with antibodies against CD68 and CD163.
Results. According to the results of an immunohistochemical study, it was found that the expression of CD68-positive macrophages of the M1 type is significantly higher in the tissue of samples of BC with microcalcifications, compared to samples of the control group (60.85 ± 2.71 cells in the field of view vs. 51.14 ± 2.89, p < 0.05). On the other hand, it was established that the average value of CD163 expression in group I was 53.21 ± 3.05 against 65.57 ± 3.75 (p ˂ 0.05) cells in the group of BC without calcification. Nevertheless, the localization of M1 and M2 macrophages in the tumor had standard features and did not differ.
A possible mechanism of the effect of microcalcifications on the polarization of macrophages is their support of chronic inflammation in cancer tissues and, thus, the development of pro-inflammatory M1 phenotype in macrophages. Further studies are needed to obtain more unambiguous conclusions.
MAIN AGE-RELATED CUTANEOUS CHANGES IN MEN GROUNDED ON THE RESULTS OF ULTRASONIC DIAGNOSTICS
Authors: Reznichenko Nataliya , Diudiun Anatolii , Reznichenko Yuriy , Smiian Kateryna
Published: June 2023

Introduction. An extremely important task of modern medical science is to preserve the health of the population. Various age violations are found in men, such as changes in the functional activity of different systems and organs. Age-related changes have a negative influence on health state, the course of different diseases, and life quality.
Materials and Methods. 120 men aged 25–64 years were examined. They were divided into four clinical groups according to the age of patients: I group – 25–34 years old, II group – 35–44 years old, III – 45–54 years old, and IV – 55–64 years old. We proposed the use of Cratal and Quercetin medications for 30 days for men from group III, and Tiocetam-Forte for 30 days for men from group IV. Ultrasound examination and dopplerography were performed. For statistical analysis, the paired Student's t-test was used. Statistical analysis was performed using STATISTICA 6.1 software.
Results. The reduction in thickness of the different layers of the skin in men of older age groups was registered. Low levels of flow velocity (its maximum and average figures), as well as high resistance index and pulse activity index, were observed in males of mature age. In cases, when antioxidants, nootropics, and vasoprotectives were prescribed for prophylaxis, flow velocity (its maximum and average figures) increased in skin vessels, while resistance index and pulse activity index dеcreased.
Conclusions. It was shown in the investigation that the use of antioxidants, nootropics, and vasoprotectives were effective for the prevention of skin aging and blood-flow violations in it in males of older age groups.
Creating an automated system for monitoring emergency situations with a radiation factor in Bryansk region
Authors: Apanasyuk O. N. , Gavrilov S. L. , Shikin S. A. , Pimenov A. E.
Published: June 2023

The article describes the structure and composition of an automated emergency monitoring system (AEMS) with a radiation factor designed to perform prompt emergency rescue operations in radioactively contaminated territories (RCT) in Bryansk region and to localize emergency zones (EZ). The study analyzed scientifi publications and patents on radiation control and environmental monitoring in case of radiation emergencies. Territorial automated systems for  monitoring radiation situations (ASMRS) and mobile means for monitoring radiation situations (RS) using unmanned aerial vehicles were explored. The integrated monitoring system for protecting the population (KSM-ZN), including in radioactively contaminated areas, in Bryansk region was described. Functions and structure of AEMS means were described. It was concluded that the AEMS can improve the effi ncy of response to radiation emergencies and decisionmaking in protecting the population and territory by transmitting real-time data on RS monitoring in the emergency zone and current assessment of the emergency and environmental situation for prompt notification about the danger.
Rules-Based Optimal Mitigation of Economic Uncertainty
Authors: Gan Pei-Tha  , Kwek Kian-Teng
Published: June 2023

A notable attribute of the empirical studies on monetary rules is that few published articles rely on the normative evaluation in eliminating unwanted economic uncertainty. To prevail over this shortcoming, this paper introduces the optimal mitigation of economic uncertainty and determines its applicability through a sample of 14 selected countries. Using the combination of the theoretically derived optimal mitigation of economic uncertainty with the empirical estimations leads to specific monetary rules. The findings of this paper provide some policy implications; the optimal mitigation of economic uncertainty can characterise the optimal use of the interest rate and exchange rate to eliminate economic uncertainty and serve as a monetary policy guide in the adjustment process to restore macroeconomic conditions of the equilibrium that eventually promote the best macroeconomic outcomes.
CEO Power, Corporate Governance Mechanisms and Earnings Quality
Authors: Dalia Ali Mostafa Hemdan  , Saif-Ur-Rehman  , Faisal Khan
Published: June 2023

This article investigated the determinants of the firm’s earnings quality (FREQ) using panel data of Egyptian listed firms to address the concerns of endogeneity and heterogeneity. We found that CEO power dynamics negatively impact FREQ. Furthermore, corporate governance’s weakening or substitution role is investigated for the negative association between CEO power dynamics and FREQ. Our findings showed that board-independence significantly weakens the impacts of CEO- ownership and CEO-tenure on FREQ. In contrast, the results fail to support the weakening or substitution role of board-independence for the negative effects of CEO-duality and CEO-political connection on FREQ. Board gender diversity is not significantly associated with FREQ. However, we found that the presence of gender critical mass serves as a substitution mechanism for the negative association between CEO power dynamics and FREQ. Lastly, we observed strong robustness for our primary analysis through propensity matching scores and difference-in-different (DID) techniques. This study brings a novelty to existing research by exploring the negative consequences of CEO power dynamics. Furthermore, it provides an insight into the constraining or weakening of the role of corporate governance. The main findings of the current study are also robust to Modified Jones model (1995) reverse-causality, DID and propensity-matching techniques.
The Impact of COVID-19 on the Construction Sector in Zimbabwe
Authors:   Department of Construction Management, Nelson Mandela University, Gqeberha 6001, SOUTH AFRICA, Chigara Benviolent ,   Department of Property Studies and Urban Design, National University of Science and Technology, Bulawayo, ZIMBABWE, Moyo Tirivavi ,   Department of Quantity Surveying, Nelson Mandela University, Gqeberha 6001, SOUTH AFRICA
Published: June 2023

The COVID-19 pandemic affected the construction industry in numerous ways. However, contextual empirical studies that enable derivation of interventions are yet to be undertaken. This study investigates the perceptions of construction professionals relative to the impact of the COVID-19 pandemic and responses on the construction sector in Zimbabwe. The study adopted a quantitative design which entailed the distribution of a web-based questionnaire among construction professionals, architects, construction/project managers, engineers and quantity surveyors from construction and consultancy firms in Bulawayo and Harare. The data were analysed based on the descriptive and inferential statistics. The results show that the COVID-19 pandemic and responses had significant effects on the construction sector. The pandemic affected the construction sector through nine main pathways; the top five being loss of income for workers, project implementation delays, job losses, increased health and safety risk, and project suspensions. Through identifying the main pathways in which the COVID-19 pandemic affected the construction industry, the study provides important insights to policymakers, construction stakeholders and researchers to plan targeted interventions or policies to mitigate the effects of the pandemic on the sector. However, because of the small sample, the study results are indicative and care should be taken when generalising the results to a large population.
Protecting Patients from Viral Respiratory Infections
Authors: Van HEZIK Ed  J.
Published: June 2023

Correspondence regarding Klompas et al, in NEJM June 14, 2023; titled ''Strategic Masking to Protect Patients from All Respiratory Viral Infections'', a plea for structured use of masks to protect against future CoV2 and other types of viral infections in a hospital setting. We do not disagree with this, but we think that instead of a passive mask barrier, another active way can also achieve this goal, but more broadly.
-The other respiratory viruses that Dr Klampos mentions are almost all of the 'single RNA enveloped' type. This is precisely the starting point of the proposed treatment method with an H2S donor, this has already been described by Dr Casola's group in some top journals (references 5,6,7).
-In addition, NAC (very safe, known for a long time, cheap and available everywhere) has also been designated as an H2S donor. This makes global application possible, especially in low-income countries. [ref 12-18]. NAC effervescent tablets are cheaper than a medically suitable mask. This also invites to include NAC as a comparator in future RC trials.
-This H2S supplementation for the restoration of innate immunity can be applied at different scales (cohorts): e.g. community, hospital, wards, barracks, cruise ships, prison, etc. Then staff and Clients/Patients can be treated combined in such a cohort.
BEDEN EĞİTİMİ VE SPOR ALANINDA YAPILAN GÖRME ENGELLİLERE YÖNELİK ARAŞTIRMALARIN SİSTEMATİK BİR ŞEKİLDE İNCELENMESİ
Authors: ŞAHİN Aykut
Published: June 2023

Bu çalışmanın amacı uluslararası dergilerde yayımlanan beden eğitimi ya da spor alanındaki görme engellilere yönelik araştırmaların sistematik bir şekilde incelenmesidir. Bu amaçla Web of Science Core Collection veritabanındaki tüm indekslerde yayımlanmış araştırmalara ait verilere ulaşılmıştır. Elde edilen veriler “Excel” ve “txt” formatlarında indirilerek analiz edilmiştir. Analizlerde yapılan araştırmaların yıllara göre sayısal anlamda ve atıf satısına göre değişimleri ile birlikte, en önde gelen yazarlar, dergiler, üniversiteler ve ülkeler doküman sayısı, atıf sayısı ve toplam bağlantı güçlerine göre incelenmiştir. Ayrıca en çok atıf alan araştırmalara ait bazı istatistiksel bilgiler ve en çok kullanılan anahtar kelimelerin ilişkisel haritası sunulmuştur. Bu alanda ilk araştırmanın 1995, en fazla araştırmanın ise 2019 yılında yapıldığı belirlenmiştir. En çok atıf alan yazarın Justin Haegele A. isimli yazar olduğu, en çok atıf alan üniversitenin Old Dominion Üniversitesi olduğu ve son olarak en çok atıf alan ülkenin Amerika Birleşik Devletleri olduğu görülmüştür. Bu alanda öne çıkan derginin Adapted Physical Activity Quarterly olduğu tespit edilmiştir. Sonuç olarak; görme engellilerin daha sağlıklı ve zinde olmaları, akranlarıyla birlikte beden eğitimi derslerine katılabilmeleri, görme yetersizliklerine rağmen fırsat eşitliğine sahip olmalarını konu edinen ve burada ortaya çıkan engelleri ortadan kaldıracak çözümler üreten araştırmaların alanyazında olduğu görülmüştür.
A non-reference detection method of the external ultrasonic liquid level switch using the PZT
Authors: Liu Bin , Xiao Yunpeng , Wang Li , Wang Wenjuan , Hu Jianqiang
Published: June 2023

Oil tank level is an important control parameter in oil depot management. According to the principle that the liquid in the oil tank can absorb the guided wave propagation energy in the tank wall, this paper studied a non-reference detection method of external ultrasonic liquid level switch based on the signal energy change value between the current and the previously liquid level detection signal. The experimental results show that the ultrasonic guided wave with the center frequency of 30 kHz is sensitive and low misjudgment to liquid level detection. According to the experimental setup, the liquid level judgment threshold is set to 0.9890. The influence of the liquid on the guided wave propagation in the tank wall decreases with the frequency of the guided wave increase. Finally, the effectiveness of the proposed method is verified on a diesel oil tank. The research of this paper provides a method for the research of oil tank external liquid level switch technology, and provides an idea for the research of oil tank liquid level measurement based on ultrasonic guided wave.
Uncertainty analysis for cylindrical structure vibration according to generalized polynomial chaos method
Authors: Luyun Chen , Yi Hong
Published: June 2023

Aiming to gain an accurate prediction model of the vibro-acoustic problem for the vibrating structure systems, the uncertainty vibration analysis for the cylindrical shell structure considering construction factors is investigated. The generalized polynomial chaos (GPC) method is used to gain the analytical solution of the free vibration for the cylindrical shell structure, in which the construction uncertainty factors, comprising the material uncertainty parameter and construction geometric uncertainty parameter, are considered. By combining the collocation method and generalized polynomial chaos method, the influence of the uncertainty construction factor on the free vibration properties for the cylindrical shell structure is verified by a numerical analysis. The results provide technical support for the design and construction of the vibrating structure for vibration and noise reducing.
Marketing Communication Barriers and How to Overcome Them
Authors: Shemchuk Maria , Komarcheva Oxsana , Shadrin Vladislav
Published: June 2023

Marketing communications create a positive brand image and attract potential consumers while providing close interaction with the target audience and increasing competitiveness. By combining approaches and tools, food companies increase the effectiveness of marketing communications and avoid communication barriers, thus achieving their profit targets in sales and advertising.

The research featured consumer preferences in the field of dairy products. The research involved such methods as observation and survey; the obtained data underwent statistical, economic, and graphic processing. The survey involved 388 residents of the city of Kemerovo and the case of the local dairy producer Naturalnoe Moloko LLC, Kemerovo.

The main barriers of marketing communications usually include barriers of perception, presentation, and interaction. The case study revealed barriers connected with installation, interaction, motivation, and comfort. The barriers could be minimized using digital marketing communications. The target audience saw the information availability about dairy companies and their products as important. This information can be provided by websites, social network accounts, and chat bots.

In modern economic environment, a company is only as successful as its marketing communications. The survey data made it possible to formulate recommendations on how dairy companies can overcome communication barriers, based on the requirements of their target audience and their preferences regarding the place of purchase, choice, and communication channels.
Non-Alcoholic Beverages from Sprouted Buckwheat: Technology and Nutritional Value
Authors: Zenkova Mariya , Melnikova Ludmila , Timofeeva Valentina
Published: June 2023

Plant-based soft drinks are a relatively new product category. Germinated, or sprouted, buckwheat (Fagopyrum esculentum Moench.) can be used as a raw material in functional beverages. It has a good potential for expanding the range of this category. The research objective was to study the effect of formulation on the production technology and nutritional value of non-alcoholic beverages from germinated buckwheat.

The study featured water-grain and water-fruit-grain mixes, as well as model samples of buckwheat drinks fortified with various fruit components, e.g., sea buckthorn, black currant, apple, etc. Standard research methods were supported by high performance liquid chromatography and atomic emission spectrometry.

Buckwheat was soaked in water at 20 ± 2°C for 46 h. This germination method resulted in a high level of microbial contamination. To ensure food safety, the water-grain suspension was brought up to 65°C for 3 min. The fruit components increased the viscosity of the dispersion medium, as well as the settling time of solid particles. The mix had to be homogenized in order to reduce the particle size and destroy the colloidal system after heating (98 ± 2°C, 1 min). The final product had a harmonious taste and contained sugars (6.72–8.04 g/100 cm3), organic acids (338.91–446.93 mg/100 cm3), minerals (0.07–0.08%), and amino acids (leucine, lysine, cystine, and tyrosine).

Buckwheat homogenization preserved the beneficial substances in the raw material. The samples fortified with sea buckthorn or blackcurrant puree had the best sensory profile and nutritional value.
Assessment-Based Optimization of Distillation Parameters
Authors: Krikunova Ludmila , Dubinina Elena , Sviridov Dmitry , Tomgorova Svetlana
Published: June 2023

The range of high-quality alcoholic beverages could be expanded by unconventional raw materials, e.g., bakery waste. Any new technology requires optimization of operating parameters at each production stage. The sensory properties of an alcoholic drink depend on the distillation mode. However, food science knows no objective methods for optimizing distillation parameters based on the biochemical composition of the raw material. The research objective was to develop a new methodology for optimizing the distillation procedure for alcoholic drinks based on unconventional raw materials.

The research featured distillates obtained from industrial samples of bakery waste. The variable factors included the distillation rate, which ranged from 5 to 17 cm3/min, and the wort acidification degree, which was pH 6.0–2.0. The composition and mass concentration of the main volatile components were determined by gas chromatography using a Thermo Trace GC Ultra device (Thermo, USA) with a flame ionization detector. The sensory evaluation was performed by a panel of qualified experts. The single-factor experiment showed that the distillation rate and the wort acidification degree affected the concentration of each volatile component in the distillate.

Using the method of pairwise correlation coefficients, the authors identified the most significant parameters: mass concentration of 1-propanol, phenylethyl alcohol, ethyl lactate, total enanthic esters, total enanthic esters vs. total esters, concentration of ethyl lactate vs. total enanthic esters, isobutanol concentration vs.1-propanol concentration. The linear pair correlation coefficients were calculated for these selected indicators, and the effect of each parameter on the sensory profile was represented as a regression model. The optimal operating parameters were determined by extremization of a two-variable function: pH 4.4 ± 0.2, speed 9.5 ± 1.0 cm3/min.

The new methodology provided for the following sequence of operations: determining the significance of the variable factor; selecting the evaluation parameters based on a single-factor experiment; determining the interaction; developing a regression model. This method can be used to calculate the optimal technological distillation parameters for other raw materials.
Effect of Essential Microelements on Proteomic Profile of Lamb Muscle Tissue Protein
Authors: Giro Tatiana , Kulikovsky Andrey , Giro Anna
Published: June 2023

Proteomic technologies make it possible to evaluate the composition of meat raw materials at different stages of processing. Proteomic studies of lamb muscle tissue help to expand scientific knowledge about the effect of essential organic microelements on the interaction of lamb muscle tissue proteins. The research objective was to identify and quantify lamb muscle tissue proteins from young sheep grown on feed additives fortified with microelements.

The research featured meat from young sheep of the Edilbaev breed aged 7 months that consumed additives Yoddar-Zn and DAFS-25 as part of their diet. The experiment lasted 105 days. The microelement composition of lamb muscle tissue underwent atomic absorption spectrometry. The proteomic profile was identified using O'Farrell’s two-dimensional gel electrophoresis (2-DE) with isoelectrofocusing in ampholine (IEF-PAGE).

Aluminum, iodine, silicon, selenium, and zinc were identified in lamb samples from young sheep that received feed additives Yoddar-Zn and DAFS-25 for 105 days. Major protein fractions included eight with a molecular weight of 12–15 kDa, 42 with 16–30 kDa, and 45 with 35–110 kDa (pI 5.0–8.0). The samples contained glutathione-S-transferase, which is responsible for biotransformation of toxic compounds, maintenance of intracellular homeostasis, and stress resistance. All the experimental samples had triose phosphate isomerase (glycolysis enzyme). The tests also revealed superoxide dismutase, which catalyzes the superoxide radical into peroxides and oxygen, thus protecting body cells from free oxygen radicals.

The research provided relevant data on the effect of innovative feed additives on the molecular mechanisms that occur in mutton muscle tissue and affect the proteomic profile of meat proteins and electrophoretic activity. The feed additives with organic microelements proved efficient. The results can be used to model and adjust autolysis in order to obtain meat with the necessary technological properties.
Typical Properties of Beverages with Different Ethanol Content: A Comparative Analysis
Authors: Lutkov Igor , Yermolin Dmitry
Published: June 2023

Non-alcoholic beer and wine are in great demand. Some of them contain carbon dioxide. Dealcoholization makes it possible to obtain high-quality drinks, but changes in flavor and taste are unavoidable. This article introduces a comparative analysis of the typical properties of beer and sparkling wine with different levels of alcohol.

The research featured industrial samples of beer and sparkling wine with different volume fractions of ethyl alcohol. The comparative analysis relied on standard research methods and included sensory evaluation, acidity, sparkling properties in terms of carbon dioxide desorption rate, carbon dioxide content, foamy properties, viscosity, phenolic substances, beer proteins, and optical characteristics.

Alcoholic beer had a better taste and possessed a typical beer flavor. The flavor and taste profile of sparkling wines depended on the raw material. The sparkling coefficient of non-alcoholic beer was 1.2–7.5% higher than that of alcoholic beer because drinks with less ethanol have better carbon dioxide solubility. For alcoholic sparkling wine, the sparkling coefficient was higher by 19.7% than for its non-alcoholic analogue due to bound forms of carbon dioxide. The foaming properties of alcoholic drinks were better than those of the non-alcoholic samples due to the higher protein content. The yellowness and optical density of drinks at a wavelength of 350 nm depended on the amount of phenolic substances. The color index of beer depended on the content of melanoidins.

The modern dealcoholization technologies make it possible to produce non-alcoholic beverages with the same sensory properties as their alcoholic prototypes. However, these technologies can be improved in terms of bound carbon dioxide, proteins, phenolic substances, and flavor.
Planning methodology for effective implementation of the rehabilitation policy for drinking water networks
Authors: Bouchraki Faiza , Hamchaoui Samir , Berreksi Ali
Published: June 2023

Algeria is currently experiencing a real water shortage and leaks in the distribution networks, which affect the water supply. To reduce losses, the authorities have adopted a rehabilitation policy that requires resources that are not necessarily available. In this context, the aim of this study is to develop a decision support methodology for managers to enable them to plan urgent rehabilitation and to evaluate the benefits generated. The methodology consists of two phases: the diagnostic phase to identify a set of criteria, taking into account national specificities, and the planning phase, including the choice of Fuzzy-AHP for weighting and PROMETHEE II for ranking. An application is carried out on the Fouka network in Bejaia city (Algeria), consisting of 204 pipes. The application enabled the 204 pipes to be ranked in order of urgency and the benefits generated to be assessed in terms of environmental, economic, social, and technical parameters. The recovered water is significant in the first 60% of rehabilitated pipes. Investment costs are recovered within 3 years of the network being fully rehabilitated. The average reduction in network age is 5 years for every 10% of pipes rehabilitated. Complaints will be 0 after 70% of the pipes are rehabilitated.
Habitar necrofronteras: afrojuvenicidio en el Pacífico colombiano
Authors: Rebolledo Henry Steven , Santana Perlaza Gustavo Adolfo
Published: June 2023

Este artículo se propone analizar los elementos que componen los paisajes y las condiciones de precarización y muerte de las juventudes afro del Pacífico sur colombiano, propias de las dinámicas de sociabilidad de la necropolítica y del proyecto global neoliberal. El texto es el resultado de una investigación etnográfica anclada en las participaciones en espacios de organizaciones culturales y en los relatos de jóvenes del municipio de Tumaco, departamento de Nariño, región del Pacífico sur colombiano. Los desarrollos teóricos presentados acá permiten analizar las formas actuales de las violencias estructurales y directas sobre las vidas precarias de jóvenes, entendiendo el juvenicidio que se da en esta región del mundo y compone el panorama de las violencias sobre las juventudes afrocolombianas —al que denominaremos afrojuvenicidio—, como parte de las dinámicas de la necropolítica.
Un acercamiento al alcance de la Corte Interamericana de Derechos Humanos en la lucha por los derechos territoriales afrodescendientes
Authors: Agudelo Carlos
Published: June 2023

Una de las herramientas usadas por los pueblos afrodescendientes de América Latina y el Caribe en la lucha por sus territorios ha sido el recurso a las instancias de justicia. Este artículo se centra en el papel que ha jugado específicamente la Corte Interamericana de Derechos Humanos (Corte IDH) en relación con las reivindicaciones territoriales de los pueblos afrodescendientes. Se trata de una investigación en curso sobre el uso de la justicia como herramienta de lucha de los pueblos afrodescendientes en América Latina y el Caribe, que se encuentra en una fase de sistematización de datos (sentencias, jurisprudencia, estudios relacionados) con elementos de análisis gradual que deberán siendo enriquecidos. De ahí la inclusión en extenso de los elementos de la documentación de la Corte IDH. Inicialmente, presentamos una visión panorámica sobre la situación de los territorios afrodescendientes. Luego, enunciamos un marco general sobre el Sistema Interamericano de Derechos humanos y los antecedentes de su implicación en casos relativos a grupos étnicos y sus territorios. Enseguida, se presenta una sistematización en orden cronológico sobre los casos que han llegado a la Corte IDH relacionados directamente con demandas de grupos afrodescendientes y reclamos territoriales. A partir de documentos de la Corte que hacen parte de los respectivos procesos, retomamos elementos de alegatos y sentencias que brindan una idea general para comprender el alcance de dichos casos. Finalmente, desarrollamos algunas reflexiones iniciales sobre las posibilidades y límites que han tenido las sentencias de la Corte IDH presentadas.
Educação para o coletivismo socialista
Authors: Reis Jonas Tarcísio
Published: June 2023

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Sensory evaluation of pacific white shrimp fed with different levels of soy protein concentrate in replacement of fish meal
Authors: Martins Vanessa Bertoldo , Vieira Felipe do Nascimento , Seiffert Walter de Quadros , Bezerra Adolfo Jatobá Medeiros
Published: June 2023

The aim of this study was to evaluate the sensory quality of Pacific white shrimp (L. vannamei) fed diets in which fish meal was replaced by soy protein concentrate. Four diets were evaluated, with different levels of replacement (33%, 66% and 100%) of fish meal by soy protein concentrate. In the sensory analysis, 50 tasters evaluated using the ordering preference test and 50 tasters evaluated the acceptability of the shrimp. The inclusion of vegetable protein source in the shrimp diet showed no difference in the discriminatory and preference ordering test and did not change the evaluated sensory attributes, which makes the product attractive to the consumer, due to the fact of consuming a product without presenting alterations in the taste.
A materialização da gestão democrática na Rede de Ensino Municipal de Manaus-AM
Authors: Moura Edilberto Santos , Uchoa Iraci Carvalho , Mourão Arminda Rachel Botelho
Published: June 2023

O artigo é o resultado de uma pesquisa de mestrado e tem como tema a gestão escolar democrática nas escolas da rede pública da cidade de Manaus (AM). O objetivo é analisar o processo da gestão escolar democrática das escolas municipais de Manaus. Utilizou-se a pesquisa de campo, de natureza qualitativa, com aplicação de entrevista semiestruturada, com uso de gravador para coleta de dados, em quatro escolas que compõem a organização estrutural da SEMED de Manaus. Com base na análise, os resultados indicam que não existe entendimento claro de como a Gestão Democrática tem sido materializada nas escolas públicas: para os entrevistados, esta categoria relaciona-se com normas, disciplinas e regras que devem ser imprescindíveis na organização escolar, levando a considerar haver a necessidade de um diálogo constante com a sociedade na perspectiva de refletir sobre qual o sentido real da gestão escolar democrática.
construção do conhecimento histórico pelos alunos do ensino médio
Authors: Bianchessi Cleber , Romanowski Joana Paulin
Published: June 2023

O artigo focaliza a prática de letramento na construção do conhecimento histórico pelos alunos do Ensino Médio considerando alternativas metodológicas para a aprendizagem histórica mediado pelo professor e pelas tecnologias digitais. O objetivo é analisar como estudantes do Ensino Médio de uma escola pública estadual na cidade de Curitiba desenvolvem a aprendizagem do conhecimento histórico. O processo de ensino e aprendizagem está fundamentado epistemologicamente na concepção da construção do conhecimento histórico de Rüsen (2001, 2006, 2007, 2009, 2011, 2015). A metodologia da investigação é de abordagem qualitativa e os dados foram registrados por meio de diário de bordo. As análises apontam que o conhecimento histórico é elaborado pelos estudantes de forma colaborativa e cooperativa mediado pelo contexto de vida, pelas intervenções do professor e facilitado pelas tecnologias digitais. Os estudantes compreendem que a inserção de recursos tecnológicos digitais ajuda no letramento e na construção do conhecimento histórico.
Non-obstructive CAD and Risk of All-cause Mortality in Middle-aged and Older
Patients: A Nine-year Follow-up and Multicentre Study
Authors: Huang Zengfa , Cao Beibei , Zhu Jinghang , Du Xinyu , Yang Yang , Li Mei , Li Zuoqin , Xiao Jianwei , Huang Jiong , Wang Xiang
Published: June 2023

Aim:

We aimed to examine all-cause mortality risk in relation to the extent of non-obstructive coronary artery disease (CAD) by coronary computed tomography angiography (CTA) in Chinese middle-aged and older patients in a multicenter study with nine-year follow-up.

Methods:

This was a retrospective, observational, multicentre study. The study population consisted of 3,240 consecutive middle-aged and older patients (age ≥ 40 years) with suspected CAD who underwent coronary CTA between June 2011 and December 2013 at three hospitals in Wuhan, China. Patients were grouped according to CAD extent for the final analysis: no CAD, 1-vessel non-obstructive CAD, 2-vessels non-obstructive CAD, and 3-vessels non-obstructive CAD. The primary endpoint was all-cause mortality. Kaplan-Meier method and Cox proportional hazards regression models were used for analysis.

Results:

A total of 2,522 patients were included in the present analysis. Of these, 188 (7.5%) deaths occurred during the median 9.0 years (interquartile range 8.6–9.4) of study follow-up. The annualized all-cause mortality rate was 0.54 (95% CI: 0.44–0.68), 0.91 (95% CI: 0.68–1.21), 1.44 (95% CI: 1.01–1.93), and 2.00 (95% CI: 1.46–2.69) for the no CAD, 1-vessel non-obstructive CAD, 2-vessels non-obstructive CAD, and 3-vessels non-obstructive CAD group, respectively. Kaplan–Meier survival curves showed a significant increase in the cumulative events associated with the extent of non-obstructive CAD (P < 0.001). In multivariate Cox regression, after adjustment for age and sex, the presence of 3-vessels non-obstructive CAD was a significant predictor of all-cause mortality (HR 1.60, 95% CI: 1.04–2.45, P = 0.032).

Conclusion:

In this cohort of Chinese middle-aged and older patients undergoing coronary CTA, the presence and extent of non-obstructive CAD, compared to no CAD, were associated with a significantly greater nine-year risk of all-cause mortality. The present findings suggest the clinical importance of the stage of non-obstructive CAD and warrant investigation of the optimal risk stratification to improve outcomes among these patients.
Sex-disaggregated Analysis of Risk Factors of COVID-19 Mortality Rates in India
Authors: Kini Anush V. , P.B. Harish , Anand Monica , Ranjan Uma
Published: June 2023

Background:

COVID-19 mortality rates vary widely across regions and sex/gender. Understanding the reasons behind such variation could help in developing suitable management strategies.

Methods:

This paper presents a comprehensive analysis of incidence and mortality rates on 2,331,363 cases and 46,239 deaths over a cumulative period of approximately 6.5 months from February to August 2020 across 411 districts of India in the age group 15-49. Together with health data from government surveys, we identify risk and protective factors across regions, socio-economic status, literacy, and sex. To obtain common indicators, we apply both machine learning techniques and statistical tests on different health factors. We also identify positive and negative correlates at multiple population scales by dividing the cohort into sub-cohorts formed from two Indian states that were further segregated by sex.

Results:

We show that males and females differ in their risk factors for mortality. While obesity (lasso regression coefficient: KA=0.5083, TN=0.318) is the highest risk factor for males, anemia (KA=0.3048, TN=0.046) is the highest risk factor for females. Further, anemia (KA=-0.0958, TN=-0.2104) is a protective factor for males, while obesity (KA=-0.0223, TN=-0.3081) is a protective factor for females.

Conclusion:

Districts with a high prevalence of obesity pose a significantly greater risk of severe COVID-19 outcomes in males. On the other hand, in females, the prevalence of anemia in districts is notably associated with a higher risk of severe COVID-19 outcomes. It is important to consider sex-wise heterogeneity in health factors for better management of health resources.
Advanced Materials and Processing Techniques
Authors: Bhuyar-Kharkhale Smita S. , Bhuyar Sudhir S. , Potbhare Ajay K. , Nagmote Manjiri S. , Singh Nakshatra B. , Chaudhary Ratiram G.
Published: June 2023

Advanced materials and processing techniques are the backbone of the smart
industry. The smart industry could not be run without a furnish of raw materials.
Further, the raw materials could become advanced materials by employing good
processing technology. Owing to this, new advanced materials exhibit compelling
properties and applications in various fields. In the present chapter, we have provided
insight into the current development of advanced materials comprising different
fabrication methodologies and their incorporation with nanofillers, as well as their
advanced processing techniques. Moreover, advanced materials’ applications have
been emphasized in different fields, like tissue engineering, biomedical, agriculture
sector, and pesticides.
Regulators of Biomedical Devices
Authors: Beylik Umut , Akdoğan Erhan
Published: June 2023

Regulators of medical devices in the world regulate global competition in
the medical device sector, and on the other hand, they play a decisive role in security,
performance, and access issues. Technological development has also increased in the
medical device industry, and medical devices have become more important in the
diagnosis and treatment of health services. However, it is important that legal
regulations must be implemented correctly and effectively in order to prevent public
health or unethical behaviors. In this context, the regulations of the United States of
America (USA) and the European Union (EU), the leaders in the sector, along with
their high markets are discussed. In addition, medical device regulations in Japan,
China, and Brazil, which have an important position in technological development and
competition and have high potential, are also included. Considering the urgency and
possible consequences of healthcare services, it is necessary to consider the fund and
the regulations of the medical device sector separately in individual, national and
global dimensions, from macro to micro. In addition to the safety, cost, and
effectiveness of medical devices, it is important to discuss the conformity assessment,
approval system processes, and how long it takes for a medical device to be put on the
market. Considering the rapid technology change, regulations should be made to carry
out the licensing and approval processes effectively and quickly in medical device
regulations.
Entre Radicalisme et Extrémisme: Le Vlaams Belang et Le Rassemblement national en période de crise sanitaire
Authors: Ricotta Anthony
Published: June 2023

Les partis populistes dedroite radicale, qui connaissent un succès majeur en Europe, posent questionquant aux menaces qu’ils pourraient faire peser sur les démocraties libérales.En effet, ces forces politiques tendent à promouvoir des idées radicalementopposées à leurs fondements. Dans un climat de désaffection politique ambiante,qui va de pair avec la crise de confiance que connaissent les démocratiesoccidentales, le radicalisme promu par ces partis pourrait s’exacerber dans lesdiscours qu’ils tiennent, menaçant d’autant plus les principes des démocratieslibérales. Les événements insurrectionnels du 6 janvier 2022 aux États-Unis etdu 8 janvier 2023 au Brésil illustrent les issues auxquelles ces menacespeuvent donner lieu. Cet article cherche à étudier la manière dont leradicalisme des partis populistes de droite se matérialise dans leurs proposdurant une période singulière compte tenu de ses implications démocratiques :la pandémie de covid-19. Pour ce faire, une analyse thématique des discours surla démocratie du Vlaams Belang et du Rassemblement national lors de cettepériode a été conduite. La recherche montre que les partis populistes de droiteradicale promeuvent une forme de démocratie.
Exploring Artificial Intelligence using Automated Writing Evaluation for Writing Skills
Authors: Abdul Rahman Nurul Ajleaa , Zulkornain Luqmanul Hakim , Hamzah Nurul Huda
Published: June 2023

This study aims to investigate the effectiveness of AI software which is Automated Writing Evaluation (AWE) in detecting grammatical errors in improving writing skills among Malaysian public university students and examine their perceptions of AI software in improving writing skills. The findings of this study show the positive perceptions of students towards the implementation of AWE. The study provided implications for the effective use of AI software (AWE) in ESL writing classrooms. Finally, future researchers are expected to conduct research on a similar topic to enhance the impact and significance of this study
Twirling Textiles in Transit: The performance of Keretapi Sarong
Authors: Rosli Siti Nabilah , Jamalludin Nur Izzati , Saiful Bahar Afiqah Aisyah , Syed Mohammad Sharifah Faizah
Published: June 2023

Public performances revolving around public transportation continue to be a common sight in transit areas such as London's Tube and the New York subway. Malaysia is even taking a step further by allowing various performing art events to take place at stations and in transit. This exploration is carried out to investigate the possibilities of utilising public transportation services to benefit performing artists in Kuala Lumpur. This research argues that this symbiotic co-existence between transit areas and serving arts practitioners, with the case study of the Kertapi Sarong activity, would foster vibrant arts lifestyle community whereby these efforts will continue to enrich public transport commute experiences.