bluuebunny/crossref_metadata_2025 huggingface dataset:
Adjoint optimization of surface textures in mixed lubrication regime
Authors: Codrignani Andrea , Savio Daniele , Pastewka Lars , Frohnapfel Bettina , van Ostayen Ron A. J.
Published: October 2020

In this work we assess the applicability of the adjoint optimization technique for determining optimal surface topographies of two surfaces in relative motion in presence of a thin lubricant films that can cavitate. Among the existing numerical tools for topology optimization in engineering problems, the adjoint method represents a promising and versatile technique, which can also be applied to the field of full film tribology. In particular, the design of surfaces with complex textures can thoroughly benefit from this method, as it allows dealing with a large number of degrees of freedom at low computational cost. We show that this optimization method can be successfully applied to cavitating lubricant flows such as in pin-on-disc tribometers, giving the possibility to extend the results also to other typical applications such as journal and slider bearings. It is shown that the adjoint method can optimize the whole gap height distribution point by point in a more efficient way than traditional optimization approaches and parametric studies. In particular, thanks to the sensitivity analysis the adjoint method is able to find the placement and depth profile of each texture element.
Crack nucleation in brittle and quasi-brittle materials: A peridynamic analysis
Authors: Niazi Sina , Chen Ziguang , Bobaru Florin
Published: October 2020

(A final version is published in Theoretical and Applied Fracture Mechanics) Peridynamic (PD) models of bodies without pre-cracks, based on a single fracture parameter (associated with the critical fracture energy), produce different strengths when different horizon sizes are used to simulate crack nucleation under quasi-static conditions. To maintain the same strength and fracture energy under different horizon sizes, extra parameters have to be introduced in the failure model. Bilinear and trilinear bond force-strain relationships have been proposed in the literature for crack propagation in quasi-brittle materials. In this paper we study crack nucleation in a plate with a hole under quasi-static loading using bilinear and trilinear PD models. We provide analytical formulas to calibrate the models to measurable material properties. We show convergence for both strength and fracture toughness. The bilinear PD constitutive model works well for both brittle (e.g. ceramics) and quasi-brittle (e.g. concrete) systems, while the trilinear version is more suited for quasi-brittle fracture behavior. We also find that for quasi-brittle fracture, a model that accounts, stochastically, for the presence of small-scale pores/defects performs better than a homogenized model. A wedge-splitting test in concrete and crack nucleation in a quasi-isotropic composite plate with a circular hole are used to demonstrate the model’s performance. In contrast with other models, the current formulation does not depend on the sample geometry.
The role of caregiver touch in early neurodevelopment and parent-infant interactional synchrony
Authors: Carozza Sofia , Leong Victoria
Published: October 2020

Though rarely included in studies of parent-infant interactions, affectionate touch plays a unique and vital role in infant development. Previous studies in human and rodent models have established that early and consistent affectionate touch from a caregiver confers wide-ranging and holistic benefits for infant psychosocial and neurophysiological development. We begin by providing a brief review of how affectionate touch tunes the development of infant somatosensory, autonomic (stress regulation) and immune systems. Affective touch also plays a foundational role in the establishment of social affiliative bonds and early psychosocial behavior. These touch-related bonding effects are known to be mediated primarily by the oxytocin system, but touch also activates mesocorticolimbic dopamine and endogenous opioid systems which aid the development of social cognitive processes such as social learning and reward processing. We conclude by proposing a unique role for affectionate touch as an essential pathway to establishing and maintaining parent-infant interactional synchrony at behavioural, physiological and neural levels. The limitations of the current understanding of affectionate touch in infant development point to fruitful avenues for future research.
Stressor-elicited smoking and craving during a smoking cessation attempt
Authors: Schultz Megan Elizabeth , Fronk Gaylen , Jaume Natalie , Magruder Katherine , Curtin John Joseph
Published: October 2020

Stressors can undermine smokers’ attempts to quit smoking. Although contemporary theories and animal models support this idea, human research has struggled to demonstrate definitively the relationship between stressors and smoking. Researchers have begun to employ more ecologically valid methods like ecological momentary assessment to address this question, but studies focusing explicitly on stressors remain sparse and findings inconsistent. The purpose of this study was to examine the effect of stressful event intensity on smoking and craving among cigarette smokers during a quit attempt. We conducted preregistered, complementary concurrent and prospective (i.e., 8-hour lag window between stressful event and outcomes) analyses to maximize statistical power and provide temporal ordering, respectively. We also conducted follow-up moderation (lag X stressful event intensity) analyses. We hypothesized that smokers would be more likely to report both smoking and craving as the intensity of stressful events increased. Cigarette smokers (N=125; 77 male) were randomly assigned to take nicotine replacement therapy (NRT) or placebo and provided 4X daily self-reports during the first 2 weeks of a quit attempt. Stressful events increased craving and the probability of smoking in concurrent analyses, and lag moderated the effect of stressful event intensity in follow-up prospective lagged analyses. NRT reduced the probability of smoking but not craving and did not moderate the effect of stressful events on smoking or craving. This study supports a prospective relationship between stressful events and smoking/craving in situ and demonstrates that NRT does not reduce the impact of stressors on smoking or craving.
Effectiveness of Telehealth Direct Therapy for Individuals with Autism Spectrum Disorder
Authors: Nohelty Karen , Bradford Casey B. , Hirschfeld Leah , Miyake Christopher
Published: October 2020

The field of applied behavior analysis (ABA) has utilized telehealth for clinical supervision and caregiver consultation and has produced research providing evidence for the efficacy of both modalities. Research demonstrating effectiveness is crucial, as behavior analysts must ensure the services they provide are effective in order to be ethical. With the increased need for patients to access more telehealth direct services, the current study evaluated the efficacy of telehealth direct therapy to teach new skills to individuals with autism spectrum disorder (ASD). This study examined the utility of natural environment teaching and discrete trial training strategies provided over a videoconferencing platform to teach new skills directly to eight individuals with ASD. The skills acquired by each individual were taught solely through telehealth direct therapy and included skills in the language, adaptive, and social domains. In a multiple baseline design, all eight individuals acquired mastery for all targets; additionally, generalization was assessed to caregivers for some targets. The evidence suggests that telehealth is a modality that is effective and can be considered for all patients when assessing the appropriate location of treatment.
Comparative Perspectives on Racial Discrimination in Hiring: The Rise of Field Experiments
Authors: Quillian Lincoln , Midtbøen Arnfinn H.
Published: October 2020

This article reviews studies of discrimination against racial and ethnic minority groups in hiring in cross-national comparative perspective. We focus on field-experimental studies of hiring discrimination: studies that use fictitious applications from members of different racial and ethnic group to apply for actual jobs. There are more than 140 field experimental studies of hiring discrimination against ethno-racial minority groups in 30 countries. These studies show that racial and ethnic discrimination is a pervasive international phenomenon that has hardly declined over time, although levels vary significantly over countries. The comparative perspective from this body of research helps to move beyond micro-models of employer decision-making to better understand the roles of history, social context, institutional rules, and racist ideologies in producing discrimination. Some racial discrimination is driven by correlated conditions like religion, but the clues producing most discrimination on these bases are fundamentally racialized. Studies suggest that institutional rules regarding race and ethnicity in hiring can have an important influence on levels of discrimination. Suggestions for future research on discrimination are discussed.
Building Pandemic Resilience in Design: Space and Movement in Art Museums during Covid-19
Authors: Li Chenyang , Psarra Sophia
Published: October 2020

The global pandemic of COVID-19 has posed challenges in relation to how buildings re-open to use, particularly buildings attracting large numbers of visitors, such as museums and galleries. As these institutions start to reopen across the UK and internationally, a number of social distance measures have been adopted in order to safely bring people into their premises and access their collections. Building on Bill Hillier’s theorical model of spatial types and spatial structures (2019), we explore the spatial-curatorial changes implicated in the re-opening of four art museums (The National Gallery, The Tate Britain and Tate Modern in London) and one American museum (The MoMA, New York). Our purpose is not to provide practical solutions, but to set the search for spatial approaches to the re-opening of museums within a theory of spatial structure in space syntax theory and inform the design future of public buildings. We present a model of a three-layered spatial system interfacing the global and local structure of these buildings. We argue that the presence of intersecting cycles of movement in spatial layouts determines their capability for adapting to the one-way routes imposed by the pandemic. The spatial organisation of the display is a second factor influencing the reopening strategies, either limiting or optimising available spatial sequences to meet curatorial criteria.
Inclusion DOES Matter: COVID-19 as an opportunity (not a near miss) for making decisive changes in UK STEMM academia
Authors: Cebula Carla , Baines Katie Nicoll , lido catherine , Halliday Karen , Hedge Nicki , Mulvana Helen , Thijssen Job H.J. , Gauchotte-Lindsay Caroline
Published: October 2020

Prior to the COVID-19 pandemic the fields of Science, Technology, Engineering, Maths and Medicine (STEMM) in Higher Education (HE) were beginning to tackle their lack of diversity. The COVID-19 pandemic has seen the HE sector (including universities, publishers and funding bodies) enter a period of upheaval that risks reversing such progress. This article demonstrates how the unequal impact of the COVID-19 pandemic on the professional and personal lives of groups currently under-represented in academic STEMM is likely to widen and reproduce systemic inequalities already present within these fields. Evidence emerging from the streamlined COVID-19 related funding call indicates a backward step in gender equity when compared to most recent UKRI figures. The lack of data on other protected characteristics makes understanding and mitigating the damage a significant challenge. We outline specific actions that must be taken to address this challenge, ultimately arguing that academic STEMM must use this time of change as an opportunity to embed policies and practices that place equality, diversity and inclusion at the forefront.
Preservation and Development of National Languages and Cultures of the Indigenous Peoples of Russia as a Necessary Condition for Creating a Favorable Bilingual Educational Environment on the Territory of the Russian Federation
Authors: Legostaeva Oksana Vyacheslavovna
Published: October 2020

The article covers significance of cultural and educational events for development of the bilingual environment; gives definitions of the terms “bilingualism”, “bilingual educational environment” and “indigenous / small peoples”. The relevance of studying this issue is in changing approaches from 2017 in teaching national languages in bilingual and multilingual regions of the country, in changing the number of hours in teaching in native (national) languages in a secondary school, in taking into account the national-regional component in the education system of a multinational state.
The subject of the research is rapidly disappearing ethnic groups and their languages according to the classification of languages of UNESCO. The article emphasizes the importance of preserving and promoting national languages and cultures for establishing intercultural dialogue and peaceful coexistence of ethnic groups in a multinational state. The purpose of the article is to identify and draw attention to the problem of disappearance of national languages and cultures through a set of measures in the field of culture, science, education.
Research methods: study of literature on the research topic, analysis of educational programs and curricula, a comparative analysis method for describing the status of the languages.
Results. In the study, we came to the conclusion that the availability of bilingual textbooks and teaching aids with assignments built on national-Russian bilingualism, the organization of various kinds of bilingual events and their popularization in the media will help to maintain a viable level of national languages and cultures of indigenous peoples in the Russian Federation.
Political Activity of Women on the Basis of Ethnocultural Features of Kyrgyz Society
Authors: Mukasheva Rahat Mukambetovna
Published: October 2020

The author outlines that nowadays, the question of the influence of gender stereotypes on the role and participation of Kyrgyz women in politics, from a linguistic point of view, has been little studied in Kyrgyzstan. The article is devoted to the ethnocultural traditions and gender stereotypes of the Kyrgyz society that affect the activity and involvement of women in the political life of the state. The author pays attention to the role of Kyrgyz women in the history of the country, examines Kyrgyz proverbs and folk clichés, which are the folk heritage of the people. The purpose of the article is to identify ethnocultural factors that determine the gender roles of men and women, as well as their impact on society.
Research methods. During the study a descriptive method was applied. The following folklore materials were taken as a basis: Kyrgyz proverbs from "Kyrgyz makal, lakap, uchkul sozdoru" by M. Ibragimov, traditional rules of relationships between people of different ages and genders, principles of youth upbringing.
As a result of the analysis, the author concludes that the traditions and stereotypes of Kyrgyz society endow men and women with gender traditional roles: a man plays a major role in the family, in society and is engaged in “male affairs”, while a woman is assigned a secondary role, she only deals with home and family. It is emphasized that such attitudes largely limit the political activity of women.
Selection of seed stocks for propagation of apple trees in the Far East
Authors: Tokareva O. I.
Published: October 2020

The article presents the results of research on the selection of seed stocks aimed at the development of intensive horticulture in the Far Eastern region, which has great potential for growing apple fruits. There were summarized materials on the study of seed stocks of apple trees. In modern conditions in fruit growing, the most relevant direction is the creation of high-yielding apple varieties with high adaptive properties. Varieties must be early-growing, have high immunity and resistance to the most harmful pathogenic, and also have good compatibility with seed stocks that are resistant to the abiotic and biotic environmental factors of the Far Eastern region. The use of seed stocks makes it possible to propagate seedlings of the most promising varieties free from harmful viral infections without losing their genetic stability. Plantings planted with such planting material do not need expensive supports and require significantly fewer mineral fertilizers and water, because they have a powerful root system that penetrates into the deeper layers the soil. Seed stocks of the apple tree are initially free from viral infection, and, unlike the clonal stocks, do not require expensive recovery, which leads to significant material savings. High grafting on seed stock not only contributes to the accelerated entry of gardens into the productive period, but also helps protect trees from damage from sunburn and frost. The production and biological study of the seed stocks of the apple tree was carried out in the form of a collection variety study and production variety testing. The field method is used to evaluate seed stocks. The developed and scientifically substantiated methods for planting apple orchards on seed stocks make it possible to create stands that are resistant to the climate of the Far Eastern region and stably produce marketable fruits for several years. It was revealed that the Siberian berry apple tree, and the variety Ranetka Yantarnaya are the most highly adapted and can be used as a seed stock.
University Teachers Attitude Towards Inclusion, Efficacy and Intentions to Teach in Inclusive Classrooms in Higher Education
Authors: Ayub Umair , Shahzad Shumaila , Shabbir Ali Muhammad
Published: October 2020

Major objectives of this study were to assess university teachers attitude towards inclusion, their efficacy in implementing inclusive practices and their intentions to teach in inclusive classroom and to find correlation among the aforementioned study variables. The sample comprised of 180 teachers from a multidisciplinary public sector university in Faisalabad. The instruments used for data collection were (1) SACIERto assess the university teachers sentiments, attitude and concerns about inclusive education, (2) TEIP to measure the teachers self-efficacy in implementing inclusive practices and(3) TITIC to assess the teachers intentions to teach in inclusive classroom. The results show teachers positive attitudes, self-efficacy and intentions towards inclusion. There is a moderate positive significant correlation between teachers attitude and their efficacy (r = 0.42) comparatively weak between attitude and intention (r = 0.32) and strong between efficacy and intention (r = 0.75). Findings may support understanding and implementation of inclusive education at the university level in Pakistan.
The Comprehensive Analysis of Morphological Variation among 24 Tomato (Solanum Lycopersicum) Genotypes Oriented to Ornamental Breeding in Vietnam
Authors: Long Tran Thien , Minh Nguyen Hong , Anh Nguyen Tuan , Minh Hang Tran Thi , Hoa Nguyen Thi , Long Nguyen Tien , Minh Nguyen Thi
Published: October 2020

Tomato is one of the most important vegetables cultivated in Vietnam. Besides its regular consumption as a vegetable, a new demand for using tomato as a decorative plant on special occasions was identified in recent years. This study aimed to characterize new tomato accessions on their desirable morphological traits to select potential materials for further breeding programs of ornamental tomato varieties in Vietnam. Twenty-four heirloom tomato genotypes were evaluated on 19 morphological traits. Based on the describing system for tomato developed by the International Plant Genetic Resources Institute (IPGRI, 1996), significant variation was assessed in both qualitative and quantitative traits related to fruit morphology. The results of principle component analysis indicated that three main principle components explained over 60% of the total phenotypic variation. The five traits of fruit size, fruit shoulder shape, fruit cross-sectional shape, number of locules, and shape of the pistil scar were recommended as important traits for clustering tomato genotypes in this study. In addition, the 24 genotypes were classified at the coefficient of 0.39 into six different clusters. Finally, six interesting accessions, AU66, AU67, AU68, AU73, AU79, and AU83 (with strange fruit colors and shapes), were selected as potential materials for further breeding programs of ornamental tomato in Vietnam.
Desenvolvimento de treinamento acadêmico para o avanço situacional de produtores de banana orgânica
Authors: Ortega Tambaco Michael
Published: October 2020

Este trabalho de pesquisa se deve à necessidade de fazer um diagnóstico da situação da agricultura orgânica no Equador. Nesse contexto, o Equador experimentou um rápido crescimento na produção e exportação de bananas orgânicas; No entanto, a sociedade exige mudanças na comercialização global do produto; Para isso, é importante resolver esse problema estabelecendo um modelo de Comércio Justo, que contemple um preço mínimo garantido para o produto exportado, além de um prêmio que consiste em dinheiro que as organizações de produtores devem usar para melhorar as condições do produto. comunidade. A modalidade de pesquisa é qualitativa e quantitativa e o tipo de pesquisa é documental, de campo, projeto descritivo e viável; com o objetivo de atender aos requisitos de comércio justo com base nas necessidades e interesses das pessoas e grupos de agricultores que exportam diretamente seus produtos, tornando o comércio uma excelente opção de marketing para seus produtos, permitindo que eles contribuam positivamente para a geração de divisas e na formação de vínculos dinâmicos em toda a cadeia produtiva, com sua firme geração de empregos e revitalização da economia rural. Será realizado um levantamento com cem produtores, utilizando o questionário como instrumento. Os dados obtidos no processo investigativo determinarão que há uma grande falha no desenvolvimento do comércio justo entre a província de Oro e o mercado europeu. O Marco Teórico será constituído por fundamentos teóricos sobre agricultura orgânica, banana orgânica, Comércio Justo, exportação, produção, preços, selos de certificação. Em virtude disso, propõe-se o Diagnóstico Situacional da Agricultura Orgânica no Equador, para contribuir com o Comércio Justo como uma alternativa socioeconômica sustentável para pequenos produtores de banana orgânica na província de Oro para o mercado europeu.
Herramientas de apoyo y soporte para elevar el nivel del aprendizaje de la programación-informática
Authors: Molina Izurieta Rosa , Villalva Cárdenas Edgar
Published: October 2020

La Programación-Informática se ha convertido en un campo de interés científico e industrial, siendo así un componente fundamental en la formación actual de Ingenieros en Sistemas Computacionales e Ingenieros Informáticos y unidad modular complementaria en varias ramas  de las ingenierías.  Su importancia en las actividades de enseñanza y aprendizaje asociados a la programación han sido reconocidas con alto grado de dificultad; por lo cual, el presente proyecto tiene como finalidad analizar las herramientas  existentes de programación para así poder contribuir a la Universidad de Guayaquil, Facultad de Ciencias Matemáticas y Físicas, carreras CISC y CINT con el estudio cada uno de ellas, aplicando investigación científica, bibliográfica, de campo entre otras obteniendo una recolección de datos a través de encuestas, presentando un resultado de sus principales utilidades, de tal forma que se pueda  elevar el nivel de aprendizaje de los estudiantes.
La educación digital en modalidad presencial
Authors: Obando Montenegro José Enrique
Published: October 2020

La presente investigación se contextualizó en la Universidad de Guayaquil dentro del programa de investigación “reactivación del sistema de gestión de prevención de riesgos laborales”, en su proyecto “socialización de la evaluación de riesgos, establecimiento de metas y plan de implementación”, del FCI (Fondo Competitivo de Investigación), avalizado por el Vice-Rectorado de Investigación, Gestión del Conocimiento y Postgrado en Guayaquil, Ecuador. La necesidad de capacitar en el área de seguridad y salud ocupacional en función de disponer de las certificaciones SETEC(Secretaría Técnica del Sistema Nacional de Cualificaciones Profesionales) al personal administrativo y de servicio de todo nivel en el ente universitario, cuyo número a la fecha oscila entre 5000 y 6000 personas, implica tener como objetivo un escenario educativo que facilite el proceso a llevar a cabo, por lo que la tecnología digital constituye un aliado educativo a la modalidad presencial o virtual que ha sido determinada por el personal responsable del proyecto, para el desarrollo de estos cursos. En el camino de la consecución de las conclusiones, se analizaron las concepciones  tecnológicas actuales y su uso educativo, así como la necesidad de emplear la tecnología educativa, estimándose emprender el uso del gestor de aprendizaje Moodle, bajo el paradigma digital de aprendizaje en apoyo a las modalidades nombradas, dado que así se facilita el proceso educativo de cursos que se originan en sus distintas categorías y diversos destinatarios, dado el nivel de concurrencia cuyo número de accesos y consultas hace necesario prestar facilidades de aprendizaje al estudiante.
Tendências e vulnerabilidades de segurança em sistemas baseados em nuvem para processos educacionais
Authors: Govin Pamela
Published: October 2020

O constante crescimento da tecnologia chegou ao ponto em que muitos serviços que eram usados anteriormente na infraestrutura física da empresa ou organização agora podem ser fisicamente hospedados em qualquer lugar do mundo e acessados pela Internet. "Serviços na nuvem". Isso leva ao aumento da segurança e devem ser tomadas medidas para evitar ataques ao serviço. Os dados estatísticos sobre eventualidades levantadas recentemente serão analisados e várias recomendações para sua prevenção serão revisadas.
Calidad en la educación superior basado en competencias en universidades públicas
Authors: Solís L. Pedro
Published: October 2020

Existe en la actualidad una importante preocupación en los círculos universitarios por responder mejor desde el mundo académico hacia las demandas del sector productivo y a los requerimientos de los empleadores, lo cual redunda, por una parte, en una revisión de la función de la universidad en la sociedad actual, caracterizada como la sociedad del conocimiento y en un replanteamiento de los diseños curriculares tradicionales por otra. A ello se suma la masificación de la matricula asociada a una gran heterogeneidad de la oferta de carreras y programas post secundarios en instituciones de muy diversa naturaleza, lo que ha generado la urgente necesidad de asegurar que los profesionales cumplan con requerimientos para el ejercicio profesional en condiciones y niveles adecuados. Sin duda la formación basada en competencias tiene una serie de ventajas importantes para la educación superior en la formación hacia el talento humano; en particular en aquellas carreras que enfatizan lo procedimental. Entre otros aspectos, se puede señalar que la utilización de este enfoque permite expresar mejor las capacidades que tienen los egresados al momento de completar sus estudios, lo cual facilita el proceso de transición que ocurre entre el término de los estudios y la incorporación al ejercicio laboral.
Training in tourism marketing techniques used in tourism marketing companies
Authors: Valenzuela H Raúl
Published: October 2020

In the present article a dissertation is made on the deductive and inductive reasoning in the process of investigation in the operation of the techniques of tourist marketing employed by commercializing companies of tourism, reflecting in takes to the force that binds it to the history the man with the attempt to survive and have new economic resources seeks the pulsation of its product using empirical marketing taking it to the present. Where marketing techniques are used in the case of tourism is related to tourism and tourism products leading to the satisfaction of tourists and the positive response that will be the result of the correct implementation and operation.
Plataformas colaborativas para la gestión de trabajos de titulación en una IES: un estudio comparativo
Authors: Peláez López Rosario Mercedes , Lara Vásconez Cilda Beatriz
Published: October 2020

Las formas de coordinar las actividades de administración durante el último año, los reglamentos y normas han permitido que se genere cambios dentro de las instituciones de educación superior, es así como tienen origen las unidades de titulación en las diversas universidades del país, las mismas que para gestión y seguimiento de los trabajos de titulación de los estudiantes, se ha visto limitados en lo que respecta a recursos tecnológicos, aplicando simplemente procesadores de texto u hojas de cálculo, como apoyo en el desarrollo de las actividades de control, siendo así necesario involucrar activamente a las TIC, como medio de innovación en este tipo de procesos de aprendizaje. La presente investigación pretende socializar plataformas colaborativas propias de la Web 2.0, mediante un análisis comparativo, alineado a los conceptos de buenas prácticas en la gestión de proyectos y normativas de calidad para obtener los resultados propositivos en el desarrollo de los trabajos de investigación de los estudiantes. Se da a conocer, herramientas tanto propietarias como de código libre, con acceso en la nube, o con la posibilidad de ser alojadas y administradas dentro del parque tecnológico de la institución.
Metodologia para gerenciar a segurança do computador para a Internet das Coisas
Authors: Mateo Washbrum Ivette
Published: October 2020

A rede de coisas, objetos e dispositivos conectados à Internet está crescendo exponencialmente, uma vez que a implantação e o design de equipamentos foram realizados de uma maneira muito diversificada, uma vez que não há Internet das coisas IoT padrão, razão pela qual o controle e o gerenciamento da segurança do computador nas redes de conexão de dispositivos com a Internet das Coisas se tornaram pesados. O desenvolvimento de um protocolo padrão para a Internet das Coisas foi considerado, considerando as especificações dos dispositivos existentes e as tecnologias de comunicação atuais, como aquelas em fase de implantação baseadas no 5G. Com base no protocolo padrão da Internet das Coisas, é proposta uma metodologia de gerenciamento de riscos e segurança de computadores para dispositivos IoT.
FAKTOR-FAKTOR YANG MEMENGARUHI PRODUKSI LADA DI DESA KONGKOMOS KECAMATAN BASIDONDO KABUPATEN TOLITOLI
Authors: Fatmah Fatmah , Hikmah Nur , Usman
Published: October 2020

This study aims to determine the factors that influence production and the magnitude of the factors that affect the production of Pepper in Kongkomos Village, Basidondo District, Tolitoli Regency. The time of research and data collection was carried out from October to November 2018. The determination of the purpose and location was determined intentionally, based on the consideration that Kongkomos Village had the highest production in Tolidoli, Basidondo Regency. The results showed that the factors influencing Pepper Farming Production were variable land area (X1), pesticides (X2), urea fertilizer (X3) and labor (X4). Variable X (land area, pesticides, urea fertilizer and labor) simultaneously has a significant effect on the Y variable (pepper production) with a value of R2 = 0.97, which explains that the contribution of variable X (land area, perticide, urea fertilizer, labor) ) to increase the fall of the variable Y (pepper production) by 97% while the remaining 3% is caused by other factors outside the production function model analyzed. From the results of the persial test it was revealed that the variables X1 (land area) 2,968, X2 (pesticides) 2,817, X3 (urea fertilizer) 4,488 and X4 (labor) 3,104 were greater than the value of t-table 2.78 which meant that the variable X1 (area land)), X2 (pesticides), X3 (urea fertilizer) and X4 (labor) have a significant effect on pepper production.
PENERAPAN MEDIA SIMULASI PHET TERHADAP HASIL BELAJAR KONSEP DASAR IPA MAHASISWA TADRIS IPA IAIN PALU
Authors: Arda Arda
Published: October 2020

This research is pre experimental research. It aims to find out the result of students learning on forces and Newton’s laws by using PhET simulation media. Subject of this research were 18 students of Tadris IPA who programmed the Basic Concepts of Natural Sciences courses. Descriptive analysis results the mean score of the student learning outcomes before the application of PhET simulation media were 12.67 and after treatment through of PhET simulation media were 15.78. The gain based on the results of data analysis using the gain normalization were 0.42. It means that there is improvement on the students of Tadris IPA learning outcomes in medium category.
PENGGUNAAN METODE “PERANG MENTAL MATEMATIKA” DENGAN MENGGUNAKAN MEDIA KARTU PECAHAN PADA MATERI PENJUMLAHAN BILANGAN PECAHAN
Authors: Suciati Indah
Published: October 2020

Fractions are a subset of a set of real numbers. Although the form is simple and often used in everyday, but the material about fractions especially in the addition of fraction numbers is still complicated for students. To overcome this problem, a solution is given in the form of the method of " Mathematical Mental Wars ". Mathematical Mental Wars is the presentation of a fast, interesting, and interactive way for students to practice problems with variables, equations, and answers. The steps of the method of " Mental Wars Mathematics ", namely: (1) reviewing game cards, (2) reviewing traditional war card games and explaining the rules and procedures, (3) grouping students in pairs, (4) providing each pair with The set of fractional cards to be shared equally, (5) reminds students not to open cards until the game starts and (6) starts the game.
PERANAN KOMPETENSI GURU PENDIDIKAN AGAMA ISLAM (PAI) DALAM MENINGKATKAN INTERAKSI PEMBELAJARAN DI SEKOLAH
Authors: Cikka Hairuddin
Published: October 2020

PAI teachers must have 5 competencies, namely pedagogic, personality, social professional and leadership in the learning interaction. A teacher must be able to build interactions with students because learning interactions are social activities between students and their peers, students and teachers in the form of social communication in the classroom or outside the classroom
Corona-Pandemie und Lehman-Pleite – ein vorläufiger Vergleich
Authors: Petersen Thieß
Published: October 2020

Die durch die Corona-Pandemie ausgelöste globale Wirtschaftskrise ist nach der geplatzten Dotcom-Blase Anfang der 2000er-Jahre und der Lehman-Pleite 2008/09 schon die dritte große Wirtschaftskrise dieses Jahrhunderts. Doch etwas ist anders: Die beiden ersten Krisen waren das Ergebnis einer geplatzten Spekulationsblase mit der Folge, dass die Nachfrage nach Gütern und Dienstleistungen abrupt zurückging. Eine Pandemie ist hingegen ein exogener Schock, der neben einem Nachfrageeinbruch auch noch einen Produktionsrückgang hervorruft. Die aktuell vorliegenden Prognosen gehen von einem wesentlich größeren Einbruch der Weltwirtschaft aus als nach der Lehman-Pleite, was die exportorientierte deutsche Volkswirtschaft entsprechend hart trifft. Daher wird es auch schwieriger als bei den beiden vorherigen Wirtschaftskrisen dieses Jahrhunderts sein, die gesamtwirtschaftliche Produktion, die Beschäftigung und das Einkommen wieder auf das Vorkrisenniveau zu bringen.
Identification of genes in hepatocellular carcinoma induced by non-alcoholic fatty liver disease
Authors: Cai Changzhou , Song Xin , Yu Chaohui
Published: October 2020

BACKGROUND: Hepatocellular carcinoma (HCC) is the leading cause of mortality worldwide. In recent years, the incidence of HCC induced by NAFLD is growing rapidly. OBJECTIVE: To screen for new pathogenic genes and related pathways both in NAFLD and HCC, and to explore the pathogenesis of progression from NAFLD to HCC. METHODS: Gene expression microarrays (GSE74656, GSE62232) were used for identifying differentially expressed genes (DEGs). Functional enrichment and pathway enrichment analyses indicated that these DEGs were related to cell cycle and extracellular exosome, which were closely related to NAFLD and HCC development. We then used the Search Tool for the Retrieval of Interacting Genes (STRING) to establish the protein-protein interaction (PPI) network and visualized them in Cytoscape. And the overall survival (OS) analysis and gene expression validation in TCGA of hub genes was performed. RESULTS: Seven hub genes, including CDK1, HSP90AA1, MAD2L1, PRKCD, ITGB3BP, CEP192, and RHOB were identified. Finally, we verified the expression level of ITGB3BP and CEP192 by quantitative real-time PCR in vitro. CONCLUSIONS: The present study implied possible DEGs, especially the new gene CEP192, in the progression of NAFLD developing to HCC. Further rigorous experiments are required to verify the above results.
Identification of Let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer
Authors: Shee Kevin , Seigne John D. , Karagas Margaret R. , Marsit Carmen J. , Hinds John W. , Schned Alan R. , Pettus Jason R. , Armstrong David A. , Miller Todd W. , Andrew Angeline S.
Published: October 2020

BACKGROUND: Among patients diagnosed with non-muscle invasive bladder cancer (NMIBC), 30% to 70% experience recurrences within 6 to 12 years of diagnosis. The need to screen for these events every 3 to 6 months and ultimately annually by cystoscopy makes bladder cancer one of the most expensive malignancies to manage. OBJECTIVE: The purpose of this study was to identify reproducible prognostic microRNAs in resected non-muscle invasive bladder tumor tissue that are predictive of the recurrent tumor phenotype as potential biomarkers and molecular therapeutic targets. METHODS: Two independent cohorts of NMIBC patients were analyzed using a biomarker discovery and validation approach, respectively. RESULTS: miRNA Let-7f-5p showed the strongest association with recurrence across both cohorts. Let-7f-5p levels in urine and plasma were both found to be significantly correlated with levels in tumor tissue. We assessed the therapeutic potential of targeting Lin28, a negative regulator of Let-7f-5p, with small-molecule inhibitor C1632. Lin28 inhibition significantly increased levels of Let-7f-5p expression and led to significant inhibition of viability and migration of HTB-2 cells. CONCLUSIONS: We have identified Let-7f-5p as a miRNA biomarker of recurrence in NMIBC tumors. We further demonstrate that targeting Lin28, a negative regulator of Let-7f-5p, represents a novel potential therapeutic opportunity in NMIBC.
The clinical significance of interleukin 24 and its potential molecular mechanism in laryngeal squamous cell carcinoma
Authors: Tang Xiao-Zhun , Zhou Xian-Guo , Zhang Xiao-Guohui , Li Guo-Sheng , Chen Gang , Dang Yi-Wu , Huang Zhi-Guang , Li Ming-Xuan , Liang Yao , Yao Yu-Xuan , Chen Xiao-Yi , Rong Min-Hua , Huang Su-Ning
Published: October 2020

Interleukin 24 (IL24) has been documented to be highly expressed in several cancers, but its role in laryngeal squamous cell carcinoma (LSCC) remains unclarified. In this study, to reveal the function and its clinical significance of IL24 in LSCC, multiple detecting methods were used comprehensively. IL24 protein expression was remarkably higher in LSCC (n= 49) than non-cancerous laryngeal controls (n= 26) as detected by in-house immunohistochemistry. Meanwhile, the IL24 mRNA expression was also evaluated based on high throughput data from Gene Expression Omnibus, The Cancer Genome Atlas, ArrayExpress and Oncomine databases. Consistently with the protein level, IL24 mRNA expression level was also predominantly upregulated in LSCC (n= 172) compared to non-cancerous laryngeal tissues (n= 81) with the standard mean difference (SMD) being 1.25 and the area under the curve (AUC) of the summary receiver operating characteristic (sROC) being 0.89 (95% CI = 0.86–0.92). Furthermore, the related genes of IL24 and the differentially expressed genes (DEGs) of LSCC were intersected and sent for Gene ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and the protein-protein interaction (PPI) analyses. In the GO annotation, the top terms of biological process (BP), cellular component (CC) and molecular function (MF) were extracellular matrix organization, extracellular matrix, cytokine activity, respectively. The top pathway of KEGG was ECM-receptor interaction. The PPI networks indicated the top hub genes of IL24-related genes in LSCC were SERPINE1, TGFB1, MMP1, MMP3, CSF2, and ITGA5. In conclusion, upregulating expression of IL24 may enhance the occurrence of LSCC, which owns prospect diagnostic ability and therapeutic significance in LSCC.
LncRNA testis-specific transcript, Y-linked 15 (TTTY15) promotes proliferation, migration and invasion of colorectal cancer cells via regulating miR-29a-3p/DVL3 axis
Authors: Zheng Xiao-Ying , Cao Ming-Zheng , Ba Ying , Li Yue-Feng , Ye Jun-Ling
Published: October 2020

BACKGROUND: Long non-coding RNA testis-specific transcript, Y-linked 15 (TTTY15) is oncogenic in prostate cancer, however its expression and function in colorectal cancer remain largely unknown. METHODS: Paired colorectal cancer samples/normal tissues were collected, and the expression levels of TTTY15, miR-29a-3p and disheveled segment polarity protein 3 (DVL3) were examined by quantitative real-time polymerase chain reaction (qRT-PCR); TTTY15 shRNA and overexpression plasmids were transfected into HT29 and HCT-116 cell lines using lipofectamine reagent, respectively; the proliferation and colony formation were detected by CCK-8 assay and plate colony formation assay; qRT-PCR and Western blot were used to analyze the changes of miR-29a-3p and DVL3; dual-luciferase reporter gene assay was used to determine the regulatory relationships between miR-29a-3p and TTTY15, miR-29a-3p and DVL3. RESULTS: TTTY15 was significantly up-regulated in cancerous tissues of colorectal cancer samples, positively correlated with the expression of DVL3, while negatively correlated with the expression of miR-29a-3p. After TTTY15 shRNAs were transfected into colorectal cancer cells, the proliferation and metastasis of cancer cells were significantly inhibited, while TTTY15 overexpression had opposite biological effects. TTTY15 shRNA could reduce the expression of DVL3 on both mRNA and protein levels, and the luciferase activity of TTTY15 sequence was also inhibited by miR-29a-3p. DVL3 was also validated as a target gene of miR-29a-3p, and it could be repressed by miR-29a-3p mimics or TTTY15 shRNA. CONCLUSION: TTTY15 is abnormally upregulated in colorectal cancer tissues, and it can modulate the proliferation and metastasis of colorectal cancer cells. It functions as the ceRNA to regulate the expression of DVL3 by sponging miR-29a-3p.
Autonomous self-evolving forecasting models for price movement in high frequency trading: Evidence from Taiwan
Authors: Huang Chien-Feng , Wu Hsiao-Chi , Chen Po-Chun , Chang Bao Rong
Published: October 2020

Among FinTech research and applications, forecasting financial time series data has been a challenging task because this kind of data is typically quite noisy and non-stationary. A recent line of financial research centers around trading through financial data on the microscopic level, which is the holy grail of high-frequency trading (HFT), as the higher the data frequency, the more profitable opportunities may appear. The advancement in HFT modeling has also facilitated more understanding towards price formation because the supply and demand of a stock can be comprehended more easily from the microstructure of the order book. Instead of traditional statistical methods, there has been increasing demand for the development of more reliable prediction models due to the recent progress in Computational Intelligence (CI) technologies. In this study, we aim to develop novel CI-based methodologies for the forecasting task of price movement in HFT. Our goal is to conduct a study for autonomous genetic-based models that allow the forecasting systems to self-evolve. The results show that our proposed method can improve upon the previous ones and advance the current state of Fintech research.
Twitter sentiment analysis for the estimation of voting intention in the 2017 Chilean elections
Authors: Alegre Sepúlveda Tomás , Keith Norambuena Brian
Published: October 2020

In this paper, we apply sentiment analysis methods in the context of the first round of the 2017 Chilean elections. The purpose of this work is to estimate the voting intention associated with each candidate in order to contrast this with the results from classical methods (e.g., polls and surveys). The data are collected from Twitter, because of its high usage in Chile and in the sentiment analysis literature. We obtained tweets associated with the three main candidates: Sebastián Piñera (SP), Alejandro Guillier (AG) and Beatriz Sánchez (BS). For each candidate, we estimated the voting intention and compared it to the traditional methods. To do this, we first acquired the data and labeled the tweets as positive or negative. Afterward, we built a model using machine learning techniques. The classification model had an accuracy of 76.45% using support vector machines, which yielded the best model for our case. Finally, we use a formula to estimate the voting intention from the number of positive and negative tweets for each candidate. For the last period, we obtained a voting intention of 35.84% for SP, compared to a range of 34–44% according to traditional polls and 36% in the actual elections. For AG we obtained an estimate of 37%, compared with a range of 15.40% to 30.00% for traditional polls and 20.27% in the elections. For BS we obtained an estimate of 27.77%, compared with the range of 8.50% to 11.00% given by traditional polls and an actual result of 22.70% in the elections. These results are promising, in some cases providing an estimate closer to reality than traditional polls. Some differences can be explained due to the fact that some candidates have been omitted, even though they held a significant number of votes.
Fourier neural networks: A comparative study
Authors: Uteuliyeva Malika , Zhumekenov Abylay , Takhanov Rustem , Assylbekov Zhenisbek , Castro Alejandro J. , Kabdolov Olzhas
Published: October 2020

We review neural network architectures which were motivated by Fourier series and integrals and which are referred to as Fourier neural networks. These networks are empirically evaluated in synthetic and real-world tasks. Neither of them outperforms the standard neural network with sigmoid activation function in the real-world tasks. All neural networks, both Fourier and the standard one, empirically demonstrate lower approximation error than the truncated Fourier series when it comes to approximation of a known function of multiple variables.