bluuebunny/crossref_metadata_2025 huggingface dataset:
CRITICAL ANALYSIS OF DNA PROFILING IN INDIA: CONSTITUTIONAL CHALLENGES AND THE WAY AHEAD
Authors: PATEL Asmita
Published: November 2021

Modern fast-progressing society has brought advancements in science and technology
touching almost all aspects of our cultural and social lives. Law enforcement is
not an exception to it with DNA Profiling being a giant leap in investigation
procedure. Despite wide application in law enforcement in many countries of
the world, India does not have a standalone law regulating the application of
DNA as a method of identification yet. Further, admissibility and reliability of
DNA evidence is a debated issue and a comprehensive study of legislative and
judicial discourse is necessary to appreciate its value and bring reformation in
the regulatory framework. This paper firstly discusses the meaning and concept
of DNA profiling including its significance and application in criminal and civil
investigations. Secondly, the present legal framework in India concerning DNA
Profiling is discussed to analyze the shortcomings and insufficiency. Thirdly, the
judicial approach towards evidentiary value of DNA Profiling is discussed. In the
fourth part of the paper, the author has addressed the constitutional challenges
to DNA profiling in India and provided suggestions and recommendations to
make it more comprehensive and accountable. The paper concludes with the
way forward in this legal reformative discourse around DNA profiling.
The nature of research is doctrinal and both primary and secondary sources of
data comprising of legislations, regulations, debates, research papers, journals,
books, newspaper articles and judgments are relied upon by the author.
Pengaruh Pemanfaatan E-Learning dan Minat Belajar Terhadap Perilaku Belajar Mahasiswa Fakultas Ekonomi Stambuk 2017 Universitas Negeri Medan
Authors: Dewi Desi Purnama , Nura Alfi
Published: November 2021

The problems in this research are students difficulties in using e-learning, students interest in learning is still low and student learning behavior is not good. The purpose of this study was to determine how the influence of the use of e-learning and interest in learning on the learning behavior of students of the Faculty of Economics, Stambuk 2017, State University of Medan. This research was conducted at the Faculty of Economics, Medan State University, which is located on Jl. Willem Iskandar Pasar V Medan. This type of research is ex post facto. The population of this study was 629 students with a sample of 86 students using simple random sampling technique. The data collection technique used is a questionnaire. Before being used, the questionnaire was tested for validity and reliability. Then the data was collected and the results of the questionnaire were analyzed using multiple regression. From the results of the partial test analysis between the use of e-learning (X1) on learning behavior (Y) from the value of  >  (4.274 > 1.663) with a significance value smaller than the 0.05 level (0.000 < 0.05) and for the significance value between learning interest (X2) and learning behavior (Y) from the value of  >  (8,575 > 1,663) with a significance value less than 0.05 level (0.000 < 0.05). Simultaneously (F test) the value is shown that  >  (121.105 > 3.11) and a significant value of 0.000 <0.05. Thus, it can be concluded that the influence of the use of e-learning and interest in learning has a positive and significant influence on the learning behavior of students of the 2017 Stambuk Economics Faculty, State University of Medan
Pengaruh Current Ratio dan Quick Ratio Terhadap Return On Asset
Authors: Novianti Delvi Rahma , Alie Juhaini , Purnamasari Endah Dewi
Published: November 2021

This study aims to analyze the effects of current ratio (CR) and quick ratio (QR) on return on assets (ROA) in the food and beverage sub-sector listed on the Indonesia Stock Exchange. Financial report data were collected through documentation, literature study, and observation. This study implemented multiple linear regression methods to analyze data. The results of the investigation prove that partially CR has a significant effect on ROA. On the other hand, QR has no significant effect on ROA. Simultaneously, CR and QR have a significant effect on ROA. This research offers empirical evidence on the discussion of CR, QR, and ROA especially for the food and beverage industry.
Kolaborasi Pemasaran Digital Menggunakan Media Sosial dan Marketplace untuk Meningkatkan Produktivitas UMKM
Authors: Anggraeny Fetty Tri , Rosida Dedin F. , Saputra Wahyu S.J. , Prasetyo Handoyo
Published: November 2021

Digital marketing is currently growing rapidly. The COVID-19 pandemic has increasingly triggered the acceleration of digital marketing, especially for SME (Small and Medium Entreprise). The growth of social media users and marketplace users both as buyers and sellers has also soared. Today's society is starting to shift to cashless transactions. Both social media and marketplace have advantages that can be collaborated as digital marketing. Social media with diverse users and a marketplace that offers easy online store management and promo programs. The collaboration of these 2 digital tools is able to increase the productivity of UMKM
Aplikasi Kasir Pada Adibah Boutique Berbasis Desktop
Authors: Mair Zaid Romegar , Sari Helen Yunita
Published: November 2021

Computers as human aids have advantages including speed, accuracy, and efficiency in data processing compared to manual systems. Computers have spread in various fields, both in the world of education and the world of work, including in the field of sales. Adibah Boutique has problems in terms of, among others, the irregularity of the management system, especially profit and loss, sales calculations (transaction activities), data collection of goods and preparation of sales reports still using manuals, cashier operators still use worksheet applications to complete each work activity, thus providing the impression of an impact that is less effective and efficient in terms of time and energy generated every day. Another problem in terms of the goods coding system and the absence of evidence between the seller and the buyer after the transaction raises a very basic problem, one solution is to use a desktop-based application that can manage sales information systems more easily thereby reducing the problems that occur in The Adibah Boutique. This application can be used as a commercial medium by the owner or staff of Adibah Boutique to make it easier to make sales transactions to consumers.
Sistem Informasi Geografis Pemetaan Area Menggunakan Arcgis (Studi Kasus Lokasi Organisasi Masyarakat (Ormas) Keagamaan Di Kota Palembang)
Authors: Rahmat Dwi Puji , Antoni Darius , Suroyo Heri
Published: November 2021

The result of this research is a web-based WebGIS or Geographic Information System design using ArcGIS software, then input into ArcGIS online and system development using the Unified Process (UP). Geographic information system for mapping the area using Arcgis (Case Study of the Location of Religious Community Organizations in Palembang City) in its use, this Web-based GIS aims to facilitate various parties, especially KESBANGPOL Palembang City and KEMENAG Palembang in mapping the distribution of CSOs, especially in this case is Religious categories that have been registered and types    the information. With the geographical information system mapping the location of religious organizations, it is hoped that it will be useful and assist in knowing the layout of the location and information for these organizations so that the delivery of information becomes more effective.
Mengidentifikasi Kebutuhan Sistem Informasi Akademik Krs (Kartu Rencana Studi) Menggunakan Teknologi Blockchain Pada Universitas Bina Darma Palembang
Authors: Purba Gilang Ramanda
Published: November 2021

The advancement of a more sophisticated period forces us to keep up with the times, especially as we approach the fourth industrial revolution, in which practically all activities rely on technological systems to assist and facilitate people in their daily lives. In the same way, an educational institution must stay up with contemporary events. Blockchain is one of the various technical systems that have arisen in recent years. Blockchain is a technology system for recording digital transaction data that is connected by cryptography and managed by a collection of computers.
Manajemen Warung Rakyat Pintar Berbasis Teknologi Informasi
Authors: Putri Luna Adhani , Antoni Darius
Published: November 2021

This study aims to help the people's stalls in improving the people's warung system into smart stalls using a technology system that is now growing rapidly, it is necessary to have a technology-based smart warung concept by managing the stalls using 4 indicators in management, namely planning, organizing, implementing. , and supervision. The research method that the author uses in this study is a qualitative method, with a case study approach. Techniques for determining the data in this study include: Observation, interviews, and documentation. Based on the results of the research obtained, the system designed for smart stalls is the POS (Point Of Sale) application system, and the internet network smart shop. The design of the technology system in the smart shop contains several simple design features to manage small businesses to medium retail businesses. The system is designed and designed for use on smartphones and tablets based on android. The system for smart stalls is designed as a cash register software to help business owners easily manage various types of businesses and shops.
COMPLICAÇÕES APÓS COVID-19, NOVOS DESAFIOS PARA O SUS
Authors: Furtado Phelipe Muniz , Davoli Lays Barros Braga , Valério Paola Marini , Ferreira Paulo Eduardo Gomes , Gonçalves Adriana da Costa
Published: November 2021

Muitas podem ser as complicações causadas pelo novo coronavírus, e todos os sistemas podem ser acometidos pelos problemas futuros deixados pelo vírus. E sabendo que esse impacto será permanente em alguns infectados o SUS (Sistema Único de Saúde) terá que se reorganizar e se adaptar para prestar uma melhor assistência. Objetivo: Identificar as possíveis complicações decorrentes da COVID-19 e identificar os desafios futuros que o SUS terá mediante as complicações da COVID-19. Métodos: Revisão de literatura foi realizada com busca nas bases de dados PUBMED e SciELO. Resultados: Foram encontrados 22 artigos sendo 5 dentro dos critérios de inclusão. Discussão: A vulnerabilidade da atenção à saúde, tanto aguda como crônica, aumentou diante a pandemia, e saber que a continuidade dos cuidados terá que continuar acontecendo aos infectados devido as complicações instaladas torna necessário a defesa do SUS e do surgimento de novas estratégias para maior e melhor assistência. Conclusão: As complicações do novo coronavirus não inúmeras e atingem todos os sistemas, e diante disto o Sistema Único de Saúde terá que se adaptar para uma melhor assistência a todos.
UM BREVE ENSAIO SOBRE A METAFÍSICA E A ONTOLOGIA
Authors: Mourão Junior Carlos Alberto
Published: November 2021

O presente artigo aborda a visão pessoal do autor acerca do lugar que a metafísica em geral, e a ontologia em particular, ocupam no saber e no pensar atual. São também discutidos alguns aspectos ontológicos do pensamento dos filósofos Edmund Husserl, Martin Heidegger e Jean-Paul Sartre. O texto é escrito por um não especialista, visando estudantes iniciantes no tema.
BİR SOSYAL MEDYA ARACI OLAN INSTAGRAM VE ALGILANAN SOSYALLEŞME: BOKSÖR ÖRNEĞİ
Authors: DEMİR Ayşe
Published: November 2021

Sosyalleşmenin kaynağında ortamda bulunan sosyal etkenler yatmaktadır. Bu etkenler, çevrimiçi öğrenme ortamlarında katılımcıların birbirileri hakkında bilgi sahibi olmalarına ve her bir katılımcıya ilişkin topluluk tarafından paylaşılan kanılar (güvenilir, kızgın, anlayışlı vb.) geliştirilmesine fırsat sağlayan yapılardır. Dolayısıyla sosyal medya platformlarında sosyalleşme her geçen gün önem kazanmaktadır. Bu çalışmanın amacı, boksörlerin demografik özellikleri temelinde bir sosyal medya aracı olan instagramı kullanım sürelerine ve paylaşımlarına ilişkin görüşleri doğrultusunda algıladıkları sosyalleşmenin incelenmesidir. Araştırmaya, İstanbul’da bulunan yıldızlar, gençler ve büyükler kategorisinde yer alan 22’si kadın (%22) ve 78’i erkek (%78) olmak üzere toplam 100 Boksör katılımcı çevrimiçi ankete gönüllü olarak katılmıştır. Araştırmada “Çevrimiçi Öğrenme Ortamlarında Algılanan Sosyalleşme” ölçeği kullanılmıştır. Ölçek 5’li likert tipi puanlamaya sahip, 10 madde ve tek alt boyuttan oluşmaktadır. Anket sorularına verilen cevapların dağılımı frekans analizi ile ve algılanan sosyalleşme ölçeğinin demografik bilgilere ve instagram hakkındaki düşüncelere göre değişimi ise bağımsız gruplarda t testi ve tek yönlü varyans analizi ile incelenmiştir. Analizler %95 güven düzeyinde SPSS 20.0 yazılımı ile incelenmiştir. Elde edilen veriler doğrultusunda, katılımcıların instagram ile ilgili düşüncelerine bakıldığında yarısından fazlasının (%64,6) instagramda takipçi sayısının fazlalığının önemli olmadığını ve yine yarısından fazlasının (%56) beğeni almanın önemli olmadığını belirttiği görülmüştür. Katılımcıların %85’inin çevresinde instagramda günlük rutinleri ya da faaliyetleri dışında daha gösterişli paylaşımlar olduğu belirlenmiştir. Katılımcıların %63’ünün instagram hesabının kendisini ve çevresini tam olarak yansıtmadığını düşündüğü; %64’ünün kendisinin ya da çevresindekilerin sahte Instagram hesabı olduğu; %57,6’sının instagramda bazı insanlardan etkilendiğini düşündüğü ve son olarak %71’inin instagramın kişilerin tanınmasında etkili bir araç olduğu ve buna inananların algılanan sosyalleşme düzeylerinin daha yüksek olduğu sonucuna varılmıştır.
DÜNYA SİSTEMLERİ ANALİZİ ÜZERİNDEN KÜRESEL MÜLTECİ KRİZİNİ ANLAMLANDIRMAK: SURİYE VE AFGANİSTAN ÖRNEKLERİ
Authors: GÜRCAN Efe Can
Published: November 2021

Günümüz dünyası, İkinci Dünya Savaşı’ndan bu yana tarihin en büyük mülteci krizi ile karşı karşıyadır. Bu nedenle, bugün mülteci sorununun daha önce hiç olmadığı kadar uluslararası bir olgu haline geldiği söylenebilir. Mevcut makale, birleşik karşılaştırma yöntemi ve dünya sistemleri kuramına dayanarak küresel mülteci krizinin hangi uluslararası dinamiklere dayandığı sorusu etrafında şekillenmiştir. Bu soruyu açıklamak için küresel mülteci krizine en canlı ve güncel örnekler arasında gösterilen Suriye ve Afganistan’a yoğunlaşılmıştır. Birleşik karşılaştırma analizi, Suriye ve Afganistan’da yaşanan mülteci krizlerinin birtakım ortak dinamikler üzerinden yükseldiğini göstermektedir. Politik-ekonomik anlamda, her iki ülke de; çeper coğrafyasına ait ülkeler olarak, dünya sistemi ile bütünleşme (inkorporasyon) dönemlerinde oluşan ciddi yapısal dengesizliklerin etkisi ile küresel mülteci krizinin oluşumunda büyük rol oynamıştır. Jeopolitik olarak, günümüz dünya sisteminde yaşanmakta olan çok kutuplulaşma ve “hegemonik kriz”, söz konusu mülteci krizinin maddi zeminini sağlamlaştırmıştır. Son olarak, jeo-kültürel dinamiklerin mevcut mülteci krizini daha da ileriye taşımaya hizmet ettiği söylenebilir. Sovyet sonrası dönemde “anti-sistemik hareketler”in ideolojik düzlemde geri çekilmesi ve etnik-dinî temelli akımların ön plana taşınması ile birlikte merkez ülkelerde yaygınlaşan ırkçılık ve yabancı düşmanlığı, “eşitsiz mübadele” mekanizmalarının meşruluğunun yeniden üretilmesini sağlamıştır.
Genetic tools derived from Staphylococcus aureus for biotechnological applications in Gram-positive bacteria
Authors:   , Dorado Morales Pedro
Published: November 2021

Staphylococcus aureus is a versatile human pathogen that has emerged as one of the most successful infectious agents of recent times, able to cause a range of diseases including skin and soft tissue infections, endocarditis, sepsis, pneumonia, osteomyelitis, bacteremia, and abscesses in organ tissues. Besides its clinical relevance, S. aureus has served as a model to study fundamental cellular processes, such as biofilm formation, the regulatory functions of small RNAs or growth and division of spherical cocci. Based on the accumulated knowledge of S. aureus biology, the availability of database resources and the advances in high-throughput genome sequencing, in this work we have aimed at developing new genetic tools derived from S. aureus for biotechnological applications in Gram-positive bacteria.
Compartimentalización Neuromuscular de los Músculos Vastus Medialis y Abductor Digiti Minimi en Personas Jóvenes
Authors:   , Guzmán Venegas Rodrigo Antonio
Published: November 2021

There is evidence that supports that the recruitment of motor units within the same muscle presents a certain heterogeneity. This heterogeneity in activation has led to the hypothesis that certain muscles could be organised neuromuscularly as functional compartments, beyond the existence that is demonstrable at a morphological level. This would imply that the motor unit grouped in certain muscle regions would show different activation levels that differ from the motor units located in other zones of the same muscle. Several studies have evidenced the existence of differential recruitment of the muscles on the trunk and limbs, demonstrated the existence of functional compartmentalization in that. This thesis sought to demonstrate the existence of a functional compartmentalization in Vastus Medialis and Abductor Digiti Minimi muscles in young people.
A Beacon-based Approach for RF Source localization in Outdoor NLOS Environment for Search and Rescue Missions
Authors: Fares Muhammad Hassan , Moradi Hadi , Shahabadi Mahmoud , Mohanna Yasser
Published: November 2021

Due to its low implementation cost, the combination of the Received Signal Strength (RSS) with the Angle of Arrival (AOA) measurements is one of the solutions for Radio Frequency (RF) source localization, especially in a Non-Line of Sight (NLOS) environment. It is critical to determine the search space for a person who is lost in rural areas where the mobile network is unavailable due to a lack of Base Tower Stations (BTS) in order to reduce search time. In this paper, we introduce a new beacon-based approach for RF source localization, where the RF signal is received in NLOS after 1-bounce reflection, by combining the information coming from both the RSS-AOA sensors and the beacons, which are used as helpers- that move along a determined path. The proposed approach relies on determining the reflector’s pose first, after which the RF source is localized. The work has been verified in simulation and the Root Mean Square Error (RMSE) is used as a performance metric for RF source localization. Results show that our proposed approach has the lowest RMSE among localization methods mentioned in the literature under the same conditions.

HIGHLIGHTS

A new beacon-based approach for RF source localization in Non-Line Of Sight (NLOS) condition

A reflector’s pose is determined based on the signal received from beacons

The reflector’s pose is used to determine the location of the RF source

One bounce reflection is considered since the chance of receiving RF signal with more reflections is very low

GRAPHICAL ABSTRACT
The Effect of the Blue and Black Light Trap on the Diversity of the Trichoptera (Caddisfly Adult) and Other Insects in Lotic and Lentic Area of Mae Tam Reservoir, Thailand
Authors: Nuntakwang Arthit , Thapanya Decha , Bozdoğan Hakan
Published: November 2021

This study was conducted using two types of light traps to collect the insects at Mae Tam Reservoir from January to April 2018. The sampling area was divided into 4 points. Two points were located at the reservoir’s bank, and the others were located at the reservoir’s outlet. The study aimed to compare the efficiency of the fluorescent tube's blue and purple light, which had a different wavelength on insect’s attraction. To compare the diversity of Trichoptera in the different stream habitats, Sørensen similarity index, Shannon-Wiener index, and Evenness index were used. The result showed that purple light could attract insects better than blue light. Hymenoptera was attracted by purple light. Coleoptera and Hemiptera were attracted by blue light. The study on the diversity of Trichoptera showed that there were 2,534 individuals of 9 families 48 species were collected. Ecnomus puro was the most abundant species (1,120 individuals). The highest Shannon-Wiener diversity index was sampling points 4 (2.10). The highest Evenness index was sampling points 4 (0.62). Sørensen similarity index showed that sampling points 3 and 4 had the highest value (67.92 %) because they were adapted from a natural creek to concrete where boulder, gravel, cobble, sand, and woody material were deposited at the stream bottom. These provided various microhabitats for insect larva to live and develop. The riparian had affected the distribution and colonization of mature insects.
Simple Current-Mode Squaring and Square-Rooting Circuits: Applications of MO-CCCCTA
Authors: Roy Suvajit , Paul Tapas Kumar , Pal Radha Raman
Published: November 2021

This work provides new designs of simple current-mode squaring and square-rooting circuits using multiple-output current controlled current conveyor transconductance amplifier (MO-CCCCTA) as an active building block. Since the proposed circuits need no other external components, they are capable of high-frequency operation and well fitted for IC fabrication. Furthermore, they are insensitive to ambient temperature and their gains can be controlled easily by adjusting the bias currents of MO-CCCCTA. Additionally, the effects of MO-CCCCTA non-idealities on the designed circuits have also been investigated and discussed. Simulation results generated through PSPICE software using TSMC 0.18 µm CMOS process parameters have been presented to justify the theoretical analysis. The static power consumption, bandwidth, and maximum linearity error in dc transfer characteristic measurement for the square-rooting circuit are found to be 0.17 mW, 445.63 MHz and 1.12 %, while for the squaring circuit they are 0.326 mW, 61.15 MHz and 2.38 %, respectively. The application of the reported circuits as a 2-input vector summation circuit has also been included to strengthen the design ideas.

HIGHLIGHTS

Simple structures of fully integrable current-mode squarers and square-rooters with low component count and lower power dissipation

The circuits are insensitive to temperature drift and their gains can be controlled easily by adjusting the bias currents of MO-CCCCTA

Bandwidth, static power dissipation, linearity error of square-rooter are 445.63 MHz, 0.17 mW & ≤ 1.12 %; and for the squarer 61.15 MHz, 0.326 mW & 2.38 %, respectively

GRAPHICAL ABSTRACT
BANDHA (Inner Lock)-MUDRA (Hand Gesture): Essences of Optimizing Health
Authors: Mukhopadhyay Dr. Kishore
Published: November 2021

Background: Bandha and Mudras are found in ancient Indian literature to stimulate internal energy. The simplest know a few things approximately our subtle body, our soul. The act of bandhas stimulates the prana and chakras. Madra is a technique to stimulate the nervous system and glands to minimize the dysfunction of the mind and the mysterious powers of man; kundalini (the inner core energy) can rise to carry our consciousness to the cosmic sense.
Purpose of the Study: To know our internal environment and the possible ways to control the internal vital energy. Through bandhas and practicing mudras one can able to get disease-free optimal health. The present article critically discussed the various aspects of bandhas and mudras and their benefit on human health and disease.
Findings: Yogic practices help to better the functioning of the thyroid, pancreas, and comparable different important glandular systems to your body. Jalandhara bandha, for example, balances the thyroid gland and thereby benefitting digestion, increase, and weight management issues. Focusing and mental integration allows many hidden and unused cycles of the brain to reach our consciousness. Various psychological problems as for example, unconscious neurosis and complex repetitive actions lose their ability to affect our lives. Madras is a practical and simultaneous way to change your life.
Conclusion: Traditionally, bandhas are classified as a part of the mudras, and are given orally from guru to student. Hatha Yoga Pradipika works with bandhas and mudras together. Bandha is heavily embedded in the mudra techniques and pranayama.
Preparation of Nanostructured SnO2-NiO Composite Semiconductor for Gas Sensor Applications
Authors: Kumar S. , Gowthaman P. , Deenathayalan J.
Published: November 2021

Electro spinning technology combined with chemical precipitation method and high-temperature calcination was used to prepare SnO2-NiO composite semiconductor nanofibers with different Sn content. Scanning electron microscope (SEM), X-ray diffractometer (XRD) and energy dispersive X-ray spectrometer (EDS) were used to characterize the morphology, structure and content of various elements of the sample. Using ethanol as the target gas, the gas sensing properties of SnO2-NiO nanofibers and the influence of Sn content on the gas sensing properties of composite nanofibers were explored. The research results show that SnO2-NiO composite nanofibers have a three-dimensional network structure, and the SnO2 composite can significantly enhance the gas sensitivity of NiO nanofibers. With increase of SnO2 content, the response sensitivity of composite fibers to ethanol gas increases, and the response sensitivity of composite nanofibers with the highest response to ethanol gas with a volume fraction of 100×10-6 at the optimal working temperature of 160℃ are13.4;It is 8.38 times the maximum response sensitivity of NiO nanofibers. Compared with the common ethanol gas sensor MQ-3 on the market, SnO2-NiO composite nanofibers have a lower optimal working temperature and higher response sensitivity, which has certain practical application value
Gastro-protective Effects of Honey in Male Wistar Rats
Authors: B.V. Owoyele , M.T. Ayinla , A.A. Esan , A. Bayo-Olugbami
Published: November 2021

Honey is consumed as food and also used in the treatments of ailment. However, honey of various types exhibit varying properties. Their therapeutic effects are determined by whether the honey is multifloral or monofloral, and also on the variety of nectars the honey is derived from. Manuka and Tualang types of honey were observed to possess anti-ulcer effects. However, no such report is available for University of Ilorin honey. This study therefore aimed to determine the gastroprotective effects of University of Ilorin honey in Wistar rats using two laboratory models for inducing ulcer (HCl/Ethanol and Indomethacin). Twenty rats each were assigned to four groups for each model of ulcer. The rats were treated for 12 days with the administration of distilled water (control), cimetidine (100 mg/kg b.w.) and University of Ilorin honey (250 mg/kg b.w. in one group and 1000 mg/kg b.w in another group). The rats were fasted for 24 hours after the last treatment. Then, the ulcerogens were given orally. After four hours, the rats were sacrificed, gastric juice was collected and the stomachs were examined for ulceration. The results revealed that pre-treatment with University of Ilorin honey reduced gastric index from 6.80±0.20 (1000 mg/kg b.w. to 2.40±0.24 (control) P<0.05 and 7.20±0.37 (1000 mg/kg b.w.) to 3.20±0.37 (control) P<0.05 in HCl/Ethanol and indomethacin induced ulcer models respectively. There was no significant difference in ulcer index between the cimetidine administered rats and the honey administered group (1000 mg/kg bw.), but the honey group (250 mg/kg bw.) was less effective than the cimetidine group in the models used. Also, there were no changes in gastric acidity in all the groups compared with the control group. In conclusion, the results showed that University of Ilorin honey has protective effect on the gastrointestinal tract which is not due to alteration of gastric acidity.
Productivity of Cowpea (Vigna unguiculata (L) Walp) genotypes under Varying Population Densities
Authors: Segun Afolabi Michael , Elizabeth Ojeleye Abiola , Kolapo Olalekan Kazeem , Alani Shittu Kabiru
Published: November 2021

To investigate the influence of three population densities (88,000, 44,000, and 29,000 plants/ha) on the growth and yield of five cowpea varieties (IT97K-461, IT97K-568-18, IT98K-131-2, IT99K-1060 and IT99K-`245), a field experiment was conducted at Teaching and Research farm of Landmark University. Growth parameters such as germination count, plant height, and number of trifoliate leaves per plant, number of branches per plant, flower production dynamics and dry matter determination were measured, while harvest index, shelling percentage, number of seeds per pod, see weight pods per plant and grain yield were measured at harvest as yield components. Data were subjected to statistical analysis of variance (ANOVA) using SAS Institute. Significant means were separated using Duncans Multiple Range Test at 5% probability level. Results revealed that there were no constant trends in growth parameters response to population density. Plant height and flower production decreased with increased population density, while number of leaves per plant and dry matter increased with increasing population density. There was no appreciable effect of population density on branching. All these parameters were significantly (p≤0.05) affected with variety, while there was no significant (p≤0.05) interaction effect. Most yield components decreased with increasing population density while grain yield however, slightly increased with increasing population density. All yield parameter and grain yield significantly varied with variety, while there were no appreciable interaction effect. In conclusion, a population density of 88,000 plants /ha gives the highest growth and grain yield. While, variety, IT97-568-18 gives the higher growth and grain yield than other varieties studied.
Survey and Chemo-physiological Assessment of Biochemical Preservatives and Physicochemical Properties of plants used for preservation of fruits
Authors: A. W. Ojewumi , B.A. Bamkefa , F. B. Kuku
Published: November 2021

The rate at which agricultural produce such as fruits are being infected by pests or spoilt as a results of lack of appropriate natural preservatives posed threat to food security and safety in many communities of Ogun State. However, there is need for study that can evaluate natural preservatives and physicochemical properties of some plants. In the present study, survey of indigenous plants commonly used for preservation of fruits was conducted using one hundred structured questionnaires randomly administered on fruit-sellers to elicit information on spoilage as threat affecting sales of fruits in Abeokuta. Also, biochemical constituents and physicochemical properties in the leaves of most plants used for fruits preservation were determined using standard procedure. Data were analysed using Statistical Analysis System. Means were separated using Duncan’s Multiple Range Test at 5% level of significance (p < 0.05). Nauclea latifolia, Chromolaena odorata, Psidium guajava, Azadirachta indica, Moringa oleifera and Aloe vera were the plants commonly used for preservation of fruits in the study area. Fruit spoilage (84.0%) was the major threat affecting the sales of fruits in Abeokuta. Saponin (0.68±0.03 mg/100g) and terpenoid (0.22±0.08 mg/100g) were significantly higher (p < 0.05) in A. indica leaves as well as alkaloid (16.49±0.01 mg/100 g) in M. oleifera leaves. Also, phenol (0.41±0.02 mg/100g) and flavonoid (0.71±0.09mg/100g) were significantly higher (p < 0.05) in C. odorata and A. vera leaves. Phytate (0.35±0.01 mg/100 g) and oxalate (0.32±0.03 mg/100 g) were significantly higher (p < 0.05) in the leaves of C. odorata. Furthermore, specific gravity of M. oleifera leaves (0.98±0.05) was significantly higher (p < 0.05) compared with leaves of other plants. Iodine value (81.65±0.03 mg/100 g) and acid value (22.72±0.07) were significantly (p < 0.05) higher in Aloe vera leaves. The study revealed that spoilage was the major challenge facing the sales of fruits in Abeokuta. Also, leaves of the plants contained high proportions of natural preservatives and physicochemical properties. Spoilage was the major challenge facing the sales of fruits, however, leaves of the plants contained high amount of preservative and physicochemical parameters that could be adopted for preservation of fruits.
Review of Business English 3.0: Hands-on Online and Virtual Collaboration Tasks
Authors: Soulé Maria-Victoria
Published: November 2021

Book review of:Business English 3.0: Hands-on Online and Virtual Collaboration TasksBy Ana Sevilla-Pavón and Anna NicolaouEditorial Comares 2019ISBN: 978-84-9045-795-5172 pages
Família, suor e lágrimas: o início de uma (possível) trajetória de profissionalização para jogadoras de categorias sub-15 e sub-17 de um clube do Rio Grande do Sul
Authors: Burch Martina , Kessler Cláudia Samuel
Published: November 2021

O presente artigo tem como objetivo analisar a constituição “profissional” de carreiras esportivas de jogadoras das equipes sub-15 e sub-17 no Esporte Clube Pelotas/Phoenix, no interior do estado do Rio Grande do Sul, Brasil, utilizando-se de observação participante e entrevistas semi-estruturadas realizadas em 2017. Ao longo deste estudo, identificou-se que fatores como recursos financeiros, mudanças no calendário de competições, apoio familiar,  afetam diretamente as perspectivas de consolidação da carreira de jovens atletas. Conclui-se, pelos relatos ouvidos, que a constituição “profissional” da carreira dessas atletas era perpassada por atos de resiliência e rebeldia, tendo em vista que, para persistir na modalidade, precisavam constantemente reforçar seu desejo de continuidade na prática e, por vezes, estabelecer conflitos com os desejos de suas famílias de origem.
Ultrasonography features of the intrinsic foot muscles in patients with and without plantar fasciitis: A novel case-control research study
Authors: Canosa-Carro Lorena , López-López Daniel , García-Bermejo Paula , Navarro-Flores Emmanuel , de Labra-Pinedo Carmen , Romero Carlos
Published: November 2021

Introduction

Plantar fasciitis (PF) is the most common cause of heel pain.(1) This condition was described as a degenerative syndrome associated with pain, lack of functionality and stiffness on the plantar fascia. The aim of the present study was to compare with ultrasound imaging (USI) the thickness and cross-sectional area of the intrinsic foot muscles between individuals with and without plantar fasciitis (PF).

Material and methods

A total of 64 volunteers from 18 to 55 years were recruited for the present study. The sample was divided in two groups: A group, composed of participants diagnosed by PF (n = 32) and B group, composed by healthy participants (n = 32).

Results

USI measurements for FBH CSA (p = 0.035) was decreasing showing statistically significant differences for the PF group, while the QP CSA (p = 0.40) was increasing reporting statistically significant differences for the PF group with respect the healthy group. The rest of the IFM did not show statistically significant differences, however in FHB, FDB, QP and AHB thicknesses and FDB CSA a slightly decrease for the PF group have been observed.

Conclusions

USI measurements showed that the CSA of the FHB muscle is reduced in patients with PF while the CSA of the QP muscle is increased in patients with PF.
Intestinal flora imbalance affects the prognosis of Parkinson's disease by regulating the expression of fecal microRNA-146a and GDNF: A Preliminary Study
Authors: Wei Hongchun , Hu Yinbao , Yang Liqing
Published: November 2021

Introduction

There is mounting evidence showing the association between the gut microbiome and Parkinson’s disease (PD). In this study, we aimed to explore the role of intestinal flora imbalance in the progression of PD and the underlying molecular mechanism involving the regulatory relationship between miR-146a and glial cell line–derived neurotrophic factor (GDNF).

Material and methods

A total of 42 PD patients were recruited in this study and grouped according to their prognosis. Real-time PCR, computational analysis and luciferase assay were carried out to explore the role of miR-146a and GDNF in PD patients as well as the regulatory relationship between the expression of miR-146a and GDNF. A rat model was used to study the effect of intestinal flora imbalance by treating the rats with Lactobacillus rhamnosus NCDC17.

Results

A lower count of total lactobaccilus and B. fragilis may predict the progression of PD. GDNF was identified as a virtual target gene of miR-146a, whose expression in fecal, plasma and cerebral tissue samples was significantly reduced in PD patients. In addition, the presence of miR-146a precursors and GDNF siRNA significantly reduced the mRNA and protein levels of GDNF in SH-SY5Y and U251 cells, and the inhibitory effect of miR-146a precursors on GDNF expression was similar to that of GDNF siRNA.

Conclusions

Taken together, the findings of this study demonstrated that GDNF is a key factor involved in the prognosis of PD. we suggested that the administration of Lactobacillus rhamnosus NCDC17 promoted the pathogenesis of PD by regulating the expression of miR-146a and GDNF in the brain.
Fabrication of Ag nanoparticles mediated by extract of plant and determination of the ‎anti-human lung cancer effects
Authors: Yan Hongjiang , Xu Ruoxuan , Song Yanmei , Gao Weinian , Zhang Helin , Jiao Xiaodan
Published: November 2021

Introduction

The present work demonstrates the synthesis of Ag nanoparticles (Ag NPs) by aqueous extract of Thymus ‎capitatus as green reductant and capping agent without any toxic reagent. ‎

Material and methods

Physicochemical characteristics of the said nanocomposite were elucidated by field emission scanning electron ‎microscopy (FE-SEM), fourier-transform infrared spectroscopy (FTIR), and UV-Vis Spectroscopy. ‎

Results

The biogenic Ag NPs are uniformly globular. The Ag NPs has been explored biologically in the anticancer and ‎antioxidant assays. In the cellular and molecular part of the recent study, the treated cells with Ag NPs were ‎assessed by MTT assay for 48h about the cytotoxicity and anti-human lung adenocarcinoma properties on ‎normal (HUVEC) and lung adenocarcinoma cell lines i.e. lung well-differentiated bronchogenic adenocarcinoma ‎‎(HLC-1), lung moderately differentiated adenocarcinoma (LC-2/ad), and lung poorly differentiated ‎adenocarcinoma (PC-14). The viability of malignant lung cell line reduced dose-dependently in the presence of ‎Ag NPs. The IC50 of Ag NPs were 209, 185, and 106 µg/mL against HLC-1, LC-2/ad, and PC-14 cell lines, ‎respectively. In the antioxidant test, the IC50 of Ag NPs and BHT against DPPH free radicals were 86 and 76 ‎‎µg/mL, respectively. ‎

Conclusions

After clinical study, Ag NPs containing Thymus capitatus leaf aqueous extract may be used to formulate a new ‎chemotherapeutic drug or supplement to treat the several types of human lung adenocarcinoma. ‎
Biometric changes after vitrectomy with silicone oil tamponade
Authors: Hosseini Simin , Faramarzi Amir , Moradian Siamak , Yaseri Mehdi
Published: November 2021

Background: The Lenstar LS 900 (Haag-Streit AG, Koeniz, Switzerland) is an optical biometer, and its measurements are highly repeatable and precise in cataractous eyes. This study investigated changes in biometric parameters, including axial length (AL), anterior chamber depth (ACD), lens thickness (LT), vitreous cavity depth (VD), and central corneal thickness (CCT) before and after three-port 23-Gauge pars plana vitrectomy with silicone oil tamponade.

Methods: This was a prospective follow-up study. Patients who were scheduled for surgery underwent a detailed slit-lamp examination and objective cycloplegic refraction preoperatively. In eligible cases, the Lenstar LS 900 was used to measure biometric parameters. At the 1-month postoperative follow-up, we repeated the same assessments for the silicone oil (SO)-filled eyes. Data were analyzed to assess the significance of changes and to test the possible correlation of values between the two time points.

Results: Twenty-three patients with a mean ± SD age of 60 ± 12 years completed the study. Postoperatively, we found a significant increase in AL and a decrease in ACD and CCT (all P < 0.05), with no significant changes in LT and VD. A significant correlation was found for ACD, CCT, and cylinder values between the two time points (all P < 0.05). Postoperatively, the spherical and cylindrical components of refraction demonstrated a hyperopic shift, but did not change statistically significantly.

Conclusions: The Lenstar LS 900 underestimated the ACD and overestimated the AL in SO-filled eyes when comparing pre- and postoperative values, in phakic as well as pseudophakic eyes. In planning for cataract surgery in this group of patients, it is more reasonable to calculate IOL power based on the biometric data of the fellow eye, although this may not eliminate possible errors. Further studies with a larger sample size, longer follow-up, and robust study design are necessary to confirm our preliminary results.
The effect of tamarind seed polysaccharidecontaining eye drop in dry eye syndrome: Results of an interventional, comparative, clinical study
Authors: Nozari Naser , Ramin Shahrokh
Published: November 2021

Background: The mainstay of dry eye treatment is artificial tear solutions. Contralateral eye comparison of 2 types of artificial tears (Xiloial versus Tearlose) in managing dry eye disease was sought in this study.

Methods: This study was a prospective, interventional, contralateral eye comparison of 2 types of artificial tears used for managing dry eye disease. The study participants were categorized into mild (13–22 points), moderate (23–32 points), or severe (33–100 points) ocular surface disease according to the baseline ocular surface disease index (OSDI) questionnaire score. Schirmer I and tear film break-up time (TBUT) tests, as well as detailed slit-lamp examinations, were performed at baseline and at the end of the study. All participants received Xiloial monodose eye drops for the right eye and Tearlose eye drops for the left eye, administered as a single drop 4 times per day. Furthermore, they were instructed to perform lid hygiene every 12 hours per day for both eyes.

Results: Thirty-five patients (70 eyes) with a mean ± standard (SD) age of 50.2 ± 13.4 years were included, and 14 (40%) were men. The mean ± SD of the OSDI score was 44.24 ± 22.59 at baseline. Of the 35 patients, 10 (28.6%), 5 (14.3%), and 20 (57.1%) had mild, moderate, and severe ocular surface disease, respectively, according to the baseline OSDI score. Compared to baseline, the mean values of both TBUT and Schirmer I tests improved significantly in both groups (both P < 0.001). In comparing the final mean values between the 2 groups, this improvement was comparable for the Schirmer I test (P = 0.179), but TBUT in Tearlose-instilled eyes improved significantly more than in the fellow eyes (P < 0.001).

Conclusions: Both Xiloial and Tearlose eye drops improved tear stability and tear production after a 2 week treatment period in eyes with dry eye disease. This improvement was comparable for tear production, but Tearlose-instilled eyes showed significantly greater improvement in tear stability. Further studies with longer follow-up and larger sample sizes could provide more reliable results as a basis for the clinical use of this TSP-containing lubricant eye drop solution in dry eye disease.
THE PROSPECTS OF HYDROSONOGRAPHY IN DIAGNOSIS OF COLON PATHOLOGY
Authors: Tishkova N. V. , Kuzmin V. D.
Published: November 2021

Objective: to assess the prospects of hydrosonography in diagnosis of various colon pathologies. Material and methods. We examined 107 patients and used the diagnostic medium based on starch and salt for the study. The results were compared with data of X-ray barium enema and fibrocolonoscopy. Results. Hydrosonography was shown to be highly informative in detection of causes of extraorganic compression, in diagnosis of mucocele of the appendix, formations larger than 1 cm in patients with colon abnormalities. The study was low-informative in diagnosis of inflammatory catarrhal illnesses and functional colon disorders in the presence of focal pathology up to 1 cm. Conclusion. Hydrosonography can not be considered as a screening method for the diagnosis of colon pathology. The decision about the necessity to conduct this study should be taken in conference with radiologists, endoscopists and sonographers.
THE ANTIBACTERIAL ACTIVITY OF OFFICINAL HERBS IN REGARD TO EXTENSIVELY ANTIBIOTIC-RESISTANT GRAM-NEGATIVE RODS
Authors: Tapalski D. V. , Tapalski F. D.
Published: November 2021

Objective: to estimate the antibacterial activity of officinal herbs available in Belarus in regard to extensively antibiotic-resistant Gram-negative bacteria. Material and methods . Minimal inhibitory concentrations and minimal bactericidal concentrations of water infusions from officinal medicinal herbs in regards to antibiotic-resistant and antibiotic-sensitive strains of Gram-negative rods have been determined. Results. 4 out of the 17 herbs revealed the expressed antibacterial activity in regards to Gram-negative non-fermenting rods. The herbs did not reveal any antibacterial activity of water infusions in regard to K. pneumoniae . Conclusion. The revealed data on the antibacterial activity make it possible to recommend medicinal herbs for additional local application along with current systemic antibiotic therapy.
THE CONTRIBUTION OF POLYMORPHIC VARIANTS P.P72R (TP53) AND P.V353A (HMMR) IN THE GENESIS OF SPORADIC BREAST CANCER
Authors: Kipen V. N. , Melnov S. B. , Smolyakova R. M.
Published: November 2021

Aim: to study the contribution of TP53 and HMMR genes to the genesis of sporadic forms of breast cancer in patients from Belarus. Material and methods. The study included 169 patients with sporadic breast cancer, molecular genetic analysis was performed by RFLP analysis and PAGE electrophoresis. Results. The polymorphic variants p.72R ( TP53 , rs1042522) and p.V353A ( HMMR , rs299290) in patients with breast cancer from Belarus were analyzed. The frequencies of genotypes and alleles prevalence in patients with breast cancer (and in the comparison group) and compared the results with the data by ESP Cohort Populations. The relation of the results of genotyping to the clinical and morphological characteristics of the tumor was analyzed. The study revealed statistically significant differences (p = 0.029) between the frequency of the prevalence of the genotype CC ( TP53 , p.R72P) and the level of expression of the Her-2/neu in the patients with breast cancer. The genotype CT ( HMMR , p.V353A) is associated with estrogen-negative breast tumors (p = 0.016). Conclusion. The polymorphic variants p.72R ( TP53 , rs1042522) and p.V353A ( HMMR , rs299290) have no significant modifying effect on the risk of sporadic breast cancer, but at the same time, there is a link between the presence of a particular genotype and the clinical morphological characteristics of the tumor.
SEVERE CARDIAC RHYTHM DISORDERS COMBINED WITH NUMEROUS CO-MORBIDITIES IN THE PRACTICE OF THE THERAPIST: CLINICAL OBSERVATION
Authors: Vasilevich N. V. , Korotayev A. V.
Published: November 2021

The work presents a clinical case of the combination of severe heart rhythm disorders in a patient with numerous comorbidities. The particular example illustrates the difficulty of choosing a rational disease management in the terms of medicinal therapy prescription.
THE EXPERIENCE OF MANAGING PREGNANCY AND LABORIN A PATIENT WITH PULMONARY THROMBOEMBOLISM
Authors: Lyzikova Yu. A. , Zakharenkova T. N. , Maltseva S. E. , Koval S. N. , Lukyanenko T. N.
Published: November 2021

A patient with full-term pregnancy complaining of dyspnoea was brought to the maternity ward. She had been not diagnosed with pulmonary thromboembolism during the in-patient observation. The conducted examinations made it possible to confirm the diagnosis, to choose therapeutic measures, as well as to hold delivery in the patient with pulmonary thromboembolism.