bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Protonation‐Triggered Generation of Acylcobalt Species from Alkyne—[Co2(CO)6] Complexes and Their Reaction with Alkenes.
Authors: Ooi Isao , Sakurai Takafumi , Takaya Jun , Iwasawa Nobuharu
Published: March 2013

Acylcobalt species generated by treatment of alkyne—[Co2(CO)6] complexes with a combination of AcOH and pyridine as promoter, undergo addition reactions with various alkenes to give the corresponding alkyl alkenyl ketones instead of Pauson—Khand products.
ChemInform Abstract: Development of a Povarov Reaction/Carbene Generation Sequence for Alkenyldiazocarbonyl Compounds.
Authors: Jadhav Appaso Mahadev , Pagar Vinayak Vishnu , Liu Rai‐Shung
Published: March 2013

The diazo‐containing cycloadducts (III) and (VII) as well as the E‐configured esters (IV) and (IX) arise stereoselective directly from the starting materials.
ChemInform Abstract: Novel Synthesis and Functionalization of ortho—ortho Disubstituted Biphenyls and a Highly Condensed Novel Heterocycle Using Radical Cyclization Reaction.
Authors: Wang C. H. , White A. R. , Schwartz S. N. , Alluri S. , Cattabiani T. M. , Zhang L. K. , Chan T. M. , Buevich A. V. , Ganguly A. K.
Published: March 2013

Lactam conjoined ortho, ortho′‐diaminated biphenyls, e.g. (IV), as well as complex heterocycles, e.g. (V), are obtained by radical cyclization of isatin derivatives.
ChemInform Abstract: NHC Broensted Base‐Catalyzed Transformations of Isochromene Derivatives: Regulation of Products by the Structures of Carbene Catalysts.
Authors: Fan Xing‐Wen , Cheng Ying
Published: March 2013

Triazole carbene and imidazole carbene organocatalysts give different isomerization products for α‐(isochromen‐1‐yl)ketones.
ChemInform Abstract: Gold(I)‐Catalyzed Regiodivergent Rearrangements: 1,2‐ and 1,2′‐Alkyl Migration in Skipped Alkynyl Ketones.
Authors: Li Wenbo , Li Yuying , Zhou Guanghua , Wu Xiangshu , Zhang Junliang
Published: March 2013

A wide range of dihydrobenzofurans and isobenzofurans as well as heterocyclic analogues thereof are prepared via gold‐catalyzed 1,2‐ or 1,2′‐alkyl migration processes.
ChemInform Abstract: Efficient Generation of Hydrogen Peroxide by Aerobic Photooxidation of 2‐Propanol Using Anthraquinone‐2‐carboxylic Acid and One‐Pot Epoxidation of α,β‐Unsaturated Ketones.
Authors: Cui Lei , Furuhashi Sohei , Tachikawa Yuma , Tada Norihiro , Miura Tsuyoshi , Itoh Akichika
Published: March 2013

Hydrogen peroxide, generated in situ from 2‐propanol in the presence of air and anthraquinone‐2‐carboxylic acid as the catalyst under irradiation with fluorescent lamp, is successfully employed for the epoxidation of α,β‐unsaturated ketones.
ChemInform Abstract: In situ Synthesized Pd Nanoparticles Supported on B‐MCM‐41: An Efficient Catalyst for Hydrogenation of Nitroaromatics in Supercritical Carbon Dioxide.
Authors: Chatterjee Maya , Ishizaka Takayuki , Suzuki Toshishige , Suzuki Akira , Kawanami Hajime
Published: March 2013

In the reaction of the substituted aromatic nitro‐compounds the order of reactivity is ortho < meta < para.
ChemInform Abstract: Efficient and Convenient Palladium‐Catalyzed Amination of Allylic Alcohols with N‐Heterocycles.
Authors: Banerjee Debasis , Jagadeesh Rajenahally V. , Junge Kathrin , Junge Henrik , Beller Matthias
Published: March 2013

The reaction proceeds without any additives and with water as sole by‐product.
ChemInform Abstract: Copper‐Catalyzed Amination of Ketene Silyl Acetals with Hydroxylamines: Electrophilic Amination Approach to α‐Amino Acids.
Authors: Matsuda Naoki , Hirano Koji , Satoh Tetsuya , Miura Masahiro
Published: March 2013

In many cases the E‐isomer is used, however, the E/Z‐geometry of the starting ketene is not relevant for the yields.
ChemInform Abstract: Highly Efficient Stereoselective Catalytic C(sp3)—H Insertions with Donor Rhodium Carbenoids Generated from Cyclopropenes.
Authors: Archambeau Alexis , Miege Frederic , Meyer Christophe , Cossy Janine
Published: March 2013

The tetrahydropyrans (II) arise as single anti diastereomers by 1,6‐C—H insertions.
ChemInform Abstract: O,O‐Diethyl Dithiophosphoric Acid Mediated Direct Synthesis of Thioamides from Aldehydes and Ketones.
Authors: Yadav Arvind K. , Srivastava Vishnu P. , Yadav Lal Dhar S.
Published: March 2013

The simple one‐pot approach proceeds via oximation of ketones and aromatic aldehydes followed by deoxygenative thioamidation.
ChemInform Abstract: Mutually Complementary Metal‐ and Organocatalysis with Collective Synthesis: Asymmetric Conjugate Addition of 1,3‐Carbonyl Compounds to Nitroenynes and Further Reactions of the Products.
Authors: Li Xiang , Li Xiaojiao , Peng Fangzhi , Shao Zhihui
Published: March 2013

This is the first metal‐catalyzed 1,4‐selective asymmetric addition of malonates to nitroenynes using a nickel(II)‐diamine catalyst.
ChemInform Abstract: A Biocatalytic Hydrogenation of Carboxylic Acids.
Authors: Ni Yan , Hagedoorn Peter‐Leon , Xu Jian‐He , Arends Isabel W. C. E. , Hollmann Frank
Published: March 2013

The hyperthermophile P.
ChemInform Abstract: Asymmetric α‐Amination of Aldehydes Catalyzed by PS‐Diphenylprolinol Silyl Ethers: Remediation of Catalyst Deactivation for Continuous Flow Operation.
Authors: Fan Xinyuan , Sayalero Sonia , Pericas Miquel A.
Published: March 2013

The newly synthesized polystyrene supported diphenylprolinol silyl ether is used as a highly active catalyst for the enantioselective α‐amination of aldehydes.
ChemInform Abstract: Chiral‐Sc Catalyzed Asymmetric Michael Addition/Protonation of Thiols with Enones in Water.
Authors: Kitanosono Taku , Sakai Masaru , Ueno Masaharu , Kobayashi Shu
Published: March 2013

A new catalytic system for the asymmetric Michael addition of thiols to enones and enantioselective protonation in water is developed.
ChemInform Abstract: A Chiral Cagelike Copper(I) Catalyst for the Highly Enantioselective Synthesis of 1,1‐Cyclopropane Diesters.
Authors: Deng Chao , Wang Li‐Jia , Zhu Jun , Tang Yong
Published: March 2013

Using phenyliodonium ylide malonate (I) the cyclopropanation of terminal (II) as well as di‐ and trisubstituted olefins proceeds highly enantioselectively.
ChemInform Abstract: Copper‐Catalyzed Difluoromethylation of β,γ‐Unsaturated Carboxylic Acids: An Efficient Allylic Difluoromethylation.
Authors: He Zhengbiao , Hu Mingyou , Luo Tao , Li Lingchun , Hu Jinbo
Published: March 2013

The reaction proceeds regioselectively, the γ‐attack products arise exclusively.
ChemInform Abstract: Free‐Radical Hydroxymethylation of Ketimines Generated in situ: A One‐Pot Multicomponent Synthesis of β,β‐Disubstituted‐β‐aminoalcohols.
Authors: Rossi Bianca , Pastori Nadia , Clerici Angelo , Punta Carlo
Published: March 2013

Oxidative radical addition of methanol and aromatic amines to simple aliphatic ketones offers a novel synthesis of β,β‐disubstituted‐β‐aminoalcohols.
ChemInform Abstract: New Ligands for Copper‐Catalyzed C—N Coupling Reactions with Aryl Halides.
Authors: Chen Dong , Yang Kai , Xiang Hua , Jiang Sheng
Published: March 2013

CHQ, combined with CuI, is found to be an optimal system for the coupling of aryl iodides, bromides and chlorides with aliphatic/aromatic amines and N‐heterocycles.
ChemInform Abstract: A Convenient One‐Pot Synthesis of (R)‐2‐Amino‐3,3,3‐trifluoro‐2‐methyl‐N‐phenylpropanamide Derivatives.
Authors: Li Tian‐Wen , Shang Pei‐Hua , Cheng Chang‐Mei , Zhao Yu‐Fen
Published: March 2013

A one‐pot procedure to synthesize enantiopure title compounds (III) from the corresponding acid (I) is reported using Vilsmeier reagent for simultaneous N‐protection and formation of the acid chloride of (I).
ChemInform Abstract: Palladium‐Catalyzed Formation of Phenolic Compounds by Reaction of Carbonyl Compounds with Carbon Dioxide.
Authors: Gao Qi , Tan Xian‐chun , Pan Ying‐ming , Wang Heng‐shan , Liang Ying
Published: March 2013

The title reaction has the unique advantage of employing CO2 as a carbon source and simple carbonyl compounds (I) as starting materials.
ChemInform Abstract: Asymmetric Aldol Reaction Catalyzed by the Self‐Assembled Nanostructures of L‐Proline Containing Amphiphilic Dipeptide: A Morphological Dependence.
Authors: Shao Mingzhe , Jin Qingxian , Zhang Li , Liu Minghua
Published: March 2013

The reaction is conducted under environmentally benign conditions.
ChemInform Abstract: Synthesis of (Z)‐3‐Aryloxy‐acrylonitriles, (E)‐3‐Aryloxy‐acrylonitriles and 3‐Cyanobenzofurans Through the Sequential Reactions of Phenols with Propiolonitriles.
Authors: Zhou Wei , Zhang Yicheng , Li Pinhua , Wang Lei
Published: March 2013

The DABCO‐promoted addition of phenols (I) to propionitriles (II) affords mainly (E)‐aryloxyacrylonitriles (III) while the sodium carbonate‐promoted reaction generates the (Z)‐isomers (IV) exclusively.
ChemInform Abstract: CuO Nanoparticles Supported on Silica: A Simple, Efficient, and Recyclable Catalyst for Hydroacylation Reactions of Aldehydes with Azodicarboxylate.
Authors: Inamdar Suleman M. , More Vinod K. , Mandal Sisir K.
Published: March 2013

A wide range of aldehydes (I), including aromatic and aliphatic derivatives, is applied in the title reaction.
ChemInform Abstract: A General and Efficient Method for the Alkoxycarbonylation of α‐Chloro Ketones.
Authors: Wahl Benoit , Bonin Helene , Mortreux Andre , Giboulot Steven , Liron Frederic , Poli Giovanni , Sauthier Mathieu
Published: March 2013

The title reaction is extended to a wide variety of chloro ketones with different types of alcohols by using much lower catalyst loading than previously reported in the literature.
ChemInform Abstract: Aminocarbonylation of (Hetero)aryl Bromides with Ammonia and Amines Using a Palladium/DalPhos Catalyst System.
Authors: Alsabeh Pamela G. , Stradiotto Mark , Neumann Helfried , Beller Matthias
Published: March 2013

Ammonia acts as both nucleophile and base in these reactions.
ChemInform Abstract: Base‐Catalyzed Efficient Tandem [3 + 3] and [3 + 2 + 1] Annulation‐Aerobic Oxidative Benzannulations.
Authors: Diallo Aboubacar , Zhao Yu‐Long , Wang He , Li Sha‐Sha , Ren Chuan‐Qing , Liu Qun
Published: March 2013

Under mild and metal‐free conditions the synthesis of substituted benzenes succeeds with molecular oxygen as sole oxidant and water as sole by‐product.
ChemInform Abstract: Tetrabutylammonium Iodide Catalyzed Allylic Sulfonylation of α‐Methyl Styrene Derivatives with Sulfonylhydrazides.
Authors: Li Xiaoqing , Xu Xiangsheng , Zhou Can
Published: March 2013

Sulfonyl radicals generated from sulfonylhydrazides (II) undergo addition to a variety of α‐methyl styrene derivatives (I), (IV), and (VI) to give the corresponding sulfones (III), (V), and (VII), respectively.
ChemInform Abstract: Solid‐Supported Rhodium(0) Nano‐/Microparticles: An Efficient Ligand‐Free Heterogeneous Catalyst for Microwave‐Assisted Suzuki—Miyaura Cross‐Coupling Reaction.
Authors: Guha Nitul Ranjan , Reddy Chennayala Bal , Aggarwal Nidhi , Sharma Dharminder , Shil Arun K. , Bandna Bandna , Das Pralay
Published: March 2013

Newly synthesized solid‐supported rhodium nanoparticles are applied in Suzuki—Miyaura cross‐coupling reactions with various aryl halides.
ChemInform Abstract: Conversion of Substituted Benzyl Ethers to Diarylmethanes. A Direct Synthesis of Diarylbenzofurans.
Authors: Kraus George A. , Chaudhary Divya
Published: March 2013

The rearrangement of aryl benzyl ethers in the presence of Lewis acid provides the desired diarylmethanes.
ChemInform Abstract: Pd‐Catalyzed Threefold Arylations of Mono‐, Di‐ and Tetra‐Bromoquinones Using Triarylbismuth Reagents.
Authors: Rao Maddali L. N. , Giri Somnath
Published: March 2013

A few highlights of the title one‐pot reaction are the use of non‐toxic and air stable triarylbismuths, the operational simplicity, short reaction times, mild conditions, and the tolerance of a wide variety of substrates.
ChemInform Abstract: Utilization of Carboxylated 1,3‐Indandione as an Electron Acceptor in Dye‐Sensitized Solar Cells.
Authors: Matsumoto Shoji , Aoki Tatsuro , Suzuki Tasutaka , Akazome Motohiro , Betto Atsushi , Suda Yasumasa
Published: March 2013

All new dyes (III) and (V) containing carboxylated 1,3‐indandiones as electron acceptors show photovoltaic sensitizing abilities.
ChemInform Abstract: Liquid‐Phase Synthesis of Cyclic Diene Diepoxides Using Metal Halides and Hydrogen Peroxide.
Authors: Alimardanov Kh. M. , Sadygov O. A. , Garibov N. I. , Abdullaeva M. Ya.
Published: March 2013

Hydroxyhalogenation of cyclic dienes using a combination of hydrogen/metal halides and H2O2 gives halohydrin derivatives, which suffer dehydrohalogenation on treatment with powdered KOH to furnish corresponding diepoxy derivatives [cf.
ChemInform Abstract: A Novel Rhodium‐Catalyzed Cascade Cyclization: Direct Synthesis of 3‐Substituted Phthalides from Aldehydes and Aromatic Acids.
Authors: Shi Xianying , Li Chao‐Jun
Published: March 2013

The title reaction is applicable to various benzoic acids and aromatic as well as aliphatic aldehydes.
ChemInform Abstract: A New Synthesis of Five‐Membered Heterocyclic Quorum Sensing Inhibitors.
Authors: Benneche Tore , Chamgordani Elahe Jafari , Reimer Inga
Published: March 2013

The reaction of heterocycles (I) and (IV) with oxalyl bromide is examined to yield E/Z‐mixtures of the title compounds after cleavage of the ‐O‐Me bond.
ChemInform Abstract: Chiral Phosphine‐Catalyzed Asymmetric Allylic Alkylation of 3‐Substituted Benzofuran‐2(3H)‐ones or Oxindoles with Morita—Baylis—Hillman Carbonates.
Authors: Wang De , Yang Yuan‐Liang , Jiang Jia‐Jun , Shi Min
Published: March 2013

Benzofuranones (I) and oxindoles (V) react with MBH carbonates (II) to afford alkylation products possessing adjacent tertiary and quaternary stereogenic centers.
ChemInform Abstract: A Novel One‐Pot Pseudo Five‐Component Isocyanide‐Based Reaction: Synthesis of 2,6‐Bis(alkylamino)‐benzofuro[5,6‐b]furan‐4,8‐dione Derivatives.
Authors: Keshipour Sajjad , Shaabani Shabnam , Shaabani Ahmad
Published: March 2013

The procedure may be of interest in diversity‐oriented synthesis and for the design of libraries concerning drugs with quinoid skeleton.
ChemInform Abstract: Mild Boronic Acid Catalyzed Nazarov Cyclization of Divinyl Alcohols in Tandem with Diels—Alder Cycloaddition.
Authors: Zheng Hongchao , Lejkowski Michal , Hall Dennis G.
Published: March 2013

A convenient one‐pot method is presented for the stereoselective synthesis of highly functionalized bicyclic compounds (III) via boronic acid catalyzed Nazarov cyclization of divinyl alcohols and subsequent Diels—Alder reaction with maleic anhydride or phenylmaleimide.
ChemInform Abstract: Chemoselective Cross‐Coupling Reactions with Differentiation Between Two Nucleophilic Sites on a Single Aromatic Substrate.
Authors: Linshoeft Julian , Heinrich Annika C. J. , Segler Stephan A. W. , Gates Paul J. , Staubitz Anne
Published: March 2013

Based on bis‐stannyl thiophene the thiophene derivative (I) is prepared through monolithiation and in situ Li‐B exchange.
ChemInform Abstract: Efficient Synthesis of α,β‐Unsaturated Alkylimines Performed with Allyl Cations and Azides: Application to the Synthesis of an Ant Venom Alkaloid.
Authors: Hayashi Kyohei , Tanimoto Hiroki , Zhang Huan , Morimoto Tsumoru , Nishiyama Yashiro , Kakiuchi Kiyomi
Published: March 2013

Based on valeraldehyde a masked precursor (XX) is prepared in nine steps.
ChemInform Abstract: Addition‐versus‐Oxygenative Cleavage: Two Contradictory Reactivities in the Reaction of N‐Benzyl‐4‐pentenylamine Catalyzed by Colloidal Nanogold under Aerobic Conditions.
Authors: Kitahara Hiroaki , Sakurai Hidehiro
Published: March 2013

The outcome and selectivity of the reaction strongly depends on the added base.
ChemInform Abstract: Indole Synthesis by Conjugate Addition of Anilines to Activated Acetylenes and an Unusual Ligand‐Free Copper(II)‐Mediated Intramolecular Cross‐Coupling.
Authors: Gao Detian , Back Thomas G.
Published: March 2013

Sulfonyl enamines are obtained preferentially as E‐isomers.
ChemInform Abstract: Organocatalytic Asymmetric Vinylogous Michael Addition of Dicyanoolefins to Imine Intermediates Generated in situ from Arenesulfonylalkylindoles.
Authors: Zhu Xing‐Li , He Wu‐Jun , Yu Liang‐Liang , Cai Chang‐Wu , Zuo Zong‐Le , Qin Da‐Bin , Liu Quan‐Zhong , Jing Lin‐Hai
Published: March 2013

The present first Michael addition provides an easy and convenient approach to C‐3 alkyl‐substituted indole derivatives with high enantioselectivities whereas diastereoselectivity depends on the cyano substrate.
ChemInform Abstract: Cesium Carbonate‐Promoted Hydroamidation of Alkynes: Enamides, Indoles and the Effect of Iron(III) Chloride.
Authors: Herrero Maria Teresa , Diaz de Sarralde Jokin , SanMartin Raul , Bravo Laura , Dominguez Esther
Published: March 2013

A simple procedure for the title synthesis is developed by using a mild base.
ChemInform Abstract: Palladium‐Catalyzed Oxidative Arylation of Trisubstituted Olefin: An Efficient Synthesis of 3‐(Disubstituted)alkylidene‐oxindoles.
Authors: Lee Hyun Ju , Kim Ko Hoon , Kim Se Hee , Kim Jae Nyoung
Published: March 2013

Under optimized conditions, the oxidative arylation of alkylidene‐oxindoles with arenes furnishes the corresponding disubstituted derivatives.
ChemInform Abstract: Synthesis of Benzoindolines via a Copper‐Catalyzed Reaction of 1‐Bromoethynyl‐2‐(cyclopropylidenemethyl)arenes with N‐Allylsulfonamide.
Authors: Li Shaoyu , Li Zhiming , Wu Jie
Published: March 2013

A novel route for the synthesis of the title compounds is developed.
ChemInform Abstract: Synthesis of [2‐(Trimethylsilyl)ethynyl]pyrazoles Based on Bis(trimethylsilyl)acetylene and Arylacetyl Chlorides.
Authors: Pankova Alena S. , Golubev Pavel R. , Ananyev Ivan V. , Kuznetsov Mikhail A.
Published: March 2013

A new general, efficient, and high chemoselective practical procedure for the synthesis of the previously unknown title compounds is developed from readily available precursors.
ChemInform Abstract: Three‐Component Reaction Between Imidazoles, Isocyanates, and Cyanophenylacetylene: A Short‐Cut to N‐(Z)‐Alkenylimidazole‐2‐carboxamides.
Authors: Belyaeva Kseniya V. , Andriyankova Ludmila V. , Nikitina Lina P. , Mal'kina Anastasiya G. , Afonin Andrei V. , Trofimov Boris A.
Published: March 2013

The carboxamides (IV) and (IX) are formed completely stereo‐ and regioselectively.
ChemInform Abstract: Catalyst Free Approach to Benzimidazoles Using Air as the Oxidant at Room Temperature.
Authors: Zhang Chun , Zhang Liangren , Jiao Ning
Published: March 2013

The reaction can be conducted on a multigram scale.
ChemInform Abstract: Bispalladacycle‐Catalyzed Michael Addition of in situ Formed Azlactones to Enones.
Authors: Weber Manuel , Jautze Sascha , Frey Wolfgang , Peters Rene
Published: March 2013

Three different pathways are presented to synthesize enantioenriched oxazole derivatives using in all cases a chiral bisimidazolinebispalladacycle FBIP catalyst.
ChemInform Abstract: Palladium(II)‐Catalyzed Oxidative Cyclization of Allylic Tosylcarbamates: Scope, Derivatization, and Mechanistic Aspects.
Authors: Joosten Antoine , Persson Andreas K. Aa. , Millet Renaud , Johnson Magnus T. , Baeckvall Jan‐E.
Published: March 2013

The reaction proceeds with complete diastereoselectivity and is scalable.
ChemInform Abstract: Copper(I)‐Catalyzed Synthesis of 1,3‐Oxazolidin‐2‐ones from Alkynes, Amines, and Carbon Dioxide under Solvent‐Free Conditions.
Authors: Zhao Jinwu , Jiang Huanfeng
Published: March 2013

CuI is shown to catalyze the fixation of carbon dioxide into the 1,3‐oxazolidin‐2‐one skeleton and thus allows the access to the required heterocycle from low‐cost materials.
ChemInform Abstract: One‐Pot Synthesis of 3,5‐Disubstituted Isoxazoles from Propargylic Alcohols Through Propargylic N‐Hydroxylamines.
Authors: Reddy Chada Raji , Vijaykumar Jonnalagadda , Jithender Enukonda , Reddy Gangireddy Pavan Kumar , Gree Rene
Published: March 2013

A mild and efficient synthesis of propargylic N‐hydroxylamines from propargylic alcohols is described and successfully extended to a one‐pot synthesis of 3,5‐disubstituted isoxazoles.
ChemInform Abstract: Tandem Reaction of Propargyl Alcohols and N‐Tosyl Hydroxylamine: Switchable Synthesis of 2,5‐Dihydroisoxazoles and 4‐Halo‐2,5‐dihydroisoxazoles.
Authors: Zhu Yuanxun , Yin Guangwei , Sun Lang , Lu Ping , Wang Yanguang
Published: March 2013

Efficient reaction conditions are reported for the conversion of propargylic alcohols (I) and (V) to 2,5‐dihydroisoxazoles (III) and the 4‐halo derivatives (IV) and (VI).
ChemInform Abstract: Regioselective Cycloaddition of C‐Aryl‐ and C‐Carbamoylnitrones to Methyl 2‐Benzylidenecyclopropanecarboxylate.
Authors: Molchanov A. P. , Tran T. Q.
Published: March 2013

Substituted methyl 5‐oxa‐6‐azaspiro[2.4]heptane‐1‐carboxylates are obtained as a mixture of two diastereoisomers by highly regioselective 1,3‐dipolar cycloaddition of C‐aryl‐ and C‐carbamoylnitrones with methyl 2‐benzylidenecyclopropanecarboxylate (I).
ChemInform Abstract: A Robust One‐Pot Synthesis of Benzothiazoles from Carboxylic Acids Including Examples with Hydroxyl and Amino Substituents.
Authors: Meghdadi Soraia , Amirnasr Mehdi , Ford Peter C.
Published: March 2013

The pharmaceutically important products include some derivatives such as (IX) which are of special interest.
ChemInform Abstract: Halogen Exchange (Halex) Reaction of 5‐Iodo‐1,2,3‐triazoles: Synthesis and Applications of 5‐Fluorotriazoles.
Authors: Worrell Brady T. , Hein Jason E. , Fokin Valery V.
Published: March 2013

An aromatic substituent at the N1‐atom causes lower yields [cf.
ChemInform Abstract: Enantioselective Iridium‐Catalyzed Allylation of Sodium Benzotriazolide: An Efficient Way to Chiral Allylbenzotriazoles.
Authors: Zhang Min , Guo Xin‐Wen , Zheng Sheng‐Cai , Zhao Xiao‐Ming
Published: March 2013

The optimized conditions allow the preparation of enantioenriched allylbenzotriazoles as mixtures of N1 and N2 regioisomers.
ChemInform Abstract: 4‐R‐7‐Nitrobenzofurazans in [3 + 2] Cycloaddition Reactions with N‐Methylazomethine Ylide.
Authors: Pechenkin S. Yu. , Starosotnikov A. M. , Bastrakov M. A. , Glukhov I. V. , Shevelev S. A.
Published: March 2013

A number of novel tetrahydroisoindole derivatives (IV) fused with a furazan ring are stereoselectively synthesized based on the 1,3‐dipolar cycloaddition of in situ generated N‐methylazomethine ylide with substituted 4‐nitrobenzofurazans.
ChemInform Abstract: Synthesis and Separation of Stereoisomeric 2,4,6,8‐Tetrasubstituted 3,7‐Dithia‐1,5‐diazabicyclo[3.3.0]octanes.
Authors: Akhmetova V. R. , Murzakova N. N. , Khabibullina G. R. , Tyumkina T. V. , Starikova Z. A. , Bushmarinov I. S. , Korzhova L. F.
Published: March 2013

Dependent on the aldehyde substituent, heterocyclization of hydrazine with aldehydes and hydrogen sulfide leads to either mixtures of four and three diastereoisomers, respectively, or proceeds diastereoselectively.
ChemInform Abstract: One‐Pot Synthesis of 2,3,4,5,6‐Pentasubstituted Tetrahydropyrans Using Lithiation—Borylation, Allylation and Prins Cyclization Reactions.
Authors: Mahmood Adeem , Ramon Suarez Jose , Thomas Stephen P. , Aggarwal Varinder K.
Published: March 2013

Starting from carbamate (I), the title reaction sequence affords pentasubstituted tetrahydropyrans with high diastereo‐ and enantioselectivity.
ChemInform Abstract: Access to Some Angular Aminochromeno[2,3‐c]pyrazole Precursors by a Domino Knoevenagel—hetero‐Diels—Alder Reaction.
Authors: Parmar Narsidas J. , Pansuriya Bhavesh R. , Labana Balvantsingh M. , Sutariya Tushar R. , Kant Rajni , Gupta Vivek K.
Published: March 2013

Newly synthesized title precursors can be transformed into the amino compounds which are potential candidates for biological and photochromic applications.
ChemInform Abstract: Magnetic Fe3O4 Nanoparticles as Efficient and Reusable Catalyst for the Green Synthesis of 2‐Amino‐4H‐chromene in Aqueous Media.
Authors: Safari Javad , Zarnegar Zohre , Heydarian Marzieh
Published: March 2013

The catalyst is found to be reusable for five cycles without any appreciable loss of its activity.
ChemInform Abstract: Lewis Acid Promoted Double Bond Isomerization of Tetrahydroxanthones.
Authors: Linsenmeier Anna M. , Braese Stefan
Published: March 2013

The isomerization products can undergo Michael / retro oxa‐Michael reaction sequences to yield substances like compound (VI).
ChemInform Abstract: Base Catalyzed Synthesis of Thiochromans and Azo‐Linked Chromenes Using Allenylphosphonates.
Authors: Pavan M. Phani , Reddy M. Nagarjuna , Kumar N. N. Bhuvan , Swamy K. C. Kumara
Published: March 2013

The reactivity of allenylphosphonates (II) towards mercaptobenzaldehydes (I) is different from that of allenoate (V) and allenyl sulfones (VII) under similar conditions.
ChemInform Abstract: Facile Preparation of Highly‐Functionalized, Nitrogen‐Bearing Diarylmethanes.
Authors: Schmink Jason R. , Tudge Matthew T.
Published: March 2013

A novel Pd‐catalyst is employed for the Suzuki coupling of heterocyclic chloromethyl derivatives with arylboronic acids under mild conditions.
ChemInform Abstract: Light Induced Synthesis of Symmetrical and Unsymmetrical Dihydropyridines in Ethyl Lactate—Water under Tunable Conditions.
Authors: Ghosh Partha Pratim , Paul Sanjay , Das Asish R.
Published: March 2013

Modified photolytic Hantzsch reaction conditions are developed for the synthesis of a variety of 1,4‐dihydropyridines including unsymmetrical derivatives (V) and (VII).
ChemInform Abstract: Two Pathways in the Reaction of tert‐Butyl 3‐Oxo‐1‐oxa‐8‐azaspiro[4.5]decane‐8‐carboxylate with N,N‐Dimethylformamide Dimethyl Acetal.
Authors: Moskalenko A. I. , Boev V. I.
Published: March 2013

The title reaction affords a mixture of two regioisomeric condensation products (III)/(IV), which can be easily transformed into isomeric spirocyclic pyrazoles on treatment with hydrazine hydrate.
ChemInform Abstract: Nickel‐Catalyzed Cycloaddition of α,β‐Unsaturated Oximes with Alkynes: Synthesis of Highly Substituted Pyridine Derivatives.
Authors: Yoshida Yuji , Kurahashi Takuya , Matsubara Seijiro
Published: March 2013

The first example of a Ni‐Catalyzed formal [4 + 2] cycloaddition of 1,3‐azadienes and alkynes furnishing highly substituted pyridines is given.
ChemInform Abstract: Synthesis of Substituted Coumarins and 2‐Quinolinones by Cycloisomerization of (Hydroxy/aminophenyl)propargyl Alcohols.
Authors: Reddy Maddi Sridhar , Thirupathi Nuligonda , Babu Madala Hari
Published: March 2013

A practical and efficient method for the synthesis of coumarins and quinolinones is described.
ChemInform Abstract: Synthesis of Azafluorenone via Oxidative Intramolecular Heck Cyclization.
Authors: Dhara Shubhendu , Ahmed Atiur , Nandi Sukla , Baitalik Shantanu , Ray Jayanta K.
Published: March 2013

A facile protocol is developed for the intramolecular Heck cyclization of 2‐bromopyridines (I) to produce azafluorenes.
ChemInform Abstract: Synthesis of 1‐(Arylsulfonyl)pyrazolo[1,5‐a]pyridines.
Authors: Mamedov S. A. , Shakhgel'dieva L. M. , Mamedova S. I. , Ladokhina N. P. , Guseinov I. Sh.
Published: March 2013

via 1,3‐dipolar cycloaddition of 1‐(arylsulfonylamino)pyridinium salts (I) dipolarophiles (II), (IV), and ketones (VI)
ChemInform Abstract: Aryne Cycloaddition with 3‐Oxidopyridinium Species.
Authors: Ren Hailong , Wu Chunrui , Ding Xiuxiu , Chen Xiaoge , Shi Feng
Published: March 2013

This is a [3+2] cycloaddition affording bicyclo[3.2.1] skeletons.
ChemInform Abstract: Rhodium(III)‐Catalyzed Oxidative C—H Functionalization of Azomethine Ylides.
Authors: Zhen Wencui , Wang Fen , Zhao Miao , Du Zhengyin , Li Xingwei
Published: March 2013

Depending on the conditions A) or B) mono‐ and diolefinated dihydrophthalazines such as (III) and (IV) are generated.
ChemInform Abstract: A Domino Desulfitative Coupling/Acylation/Hydration Process Cocatalyzed by Copper(I) and Palladium(II): Synthesis of Highly Substituted and Functionalized Pyrimidines.
Authors: Quan Zheng‐Jun , Hu Wang‐Hua , Jia Xiao‐Dong , Zhang Zhang , Da Yu‐Xia , Wang Xi‐Cun
Published: March 2013

A series of substituted pyrimidines is synthesized by the present new multicomponent reaction of pyrimidinethiones, aromatic and aliphatic alkynes (II), and a copper(I) carboxylate under modified Liebeskind—Srogl conditions.
ChemInform Abstract: Transition Metal‐Free α‐C(sp3)—H Bond Functionalization of Amines by Oxidative Cross Dehydrogenative Coupling Reaction: Simple and Direct Access to C‐4‐Alkylated 3,4‐Dihydroquinazoline Derivatives.
Authors: Kumar R. Arun , Saidulu G. , Prasad K. Rajendra , Kumar G. Sathish , Sridhar B. , Reddy K. Rajender
Published: March 2013

The novel title method for the synthesis of the compounds (III) is further extended for the unprecedented one‐pot construction of biologically important N‐heterocycles, namely, 3,4‐dihydroquinazoline derivatives like (VI) and (VIII).
ChemInform Abstract: A Concise Aqueous Phase Supramolecular Synthesis of 2‐Phenyl‐2,3‐dihydroquinazolin‐4(1H)‐one Derivatives.
Authors: Ramesh K. , Karnakar K. , Satish G. , Kumar B. S. P. Anil , Nageswar Y. V. D.
Published: March 2013

β‐Cyclodextrin is optimal as recyclable catalyst for the condensation of anthranilamide with aromatic, aliphatic and heteroaryl aldehydes for the preparation of the pharmaceutically important heterocyclic system.
ChemInform Abstract: Microwave‐Assisted, Mild, Facile, and Rapid One‐Pot Three‐Component Synthesis of Some Novel Pyrano[2,3‐d]pyrimidine‐2,4,7‐triones.
Authors: Azzam Sadeq Hamood Saleh , Pasha M. A.
Published: March 2013

No reaction is observed in the presence of aliphatic aldehydes.
ChemInform Abstract: Synthesis of Isomeric Angularly Fused Dihydroquinazolinoquinazolinones and an Unusual Oxidative Rearrangement.
Authors: Venkateswarlu Somepalli , Satyanarayana Meka , Srinivas Kolla , Aadisudhakar Kodumuri N. V. V.
Published: March 2013

Cyclization of 2‐(o‐aminophenyl)‐dihydroquinazolinones (I) with dimethylformamide dimethylacetal under basic conditions affords the title compounds (III) and (IV).
ChemInform Abstract: A Novel Method for the Synthesis of 1,8‐Dihydropyrido[2,3,4‐gh]perimidin‐7(6H)‐ones.
Authors: Aksenov A. V. , Aksenov N. A. , Kumshaeva A. B. , Smirnov A. N. , Ovcharov S. N.
Published: March 2013

Previously unknown title compounds are smoothly synthesized by treatment of perimidines (I) with β‐nitrostyrene via in situ generated oximes and subsequent Beckmann rearrangement.
ChemInform Abstract: Unusual Reaction of 1H‐Perimidines with Sodium Azide and Benzoyl Hydrazine in Polyphosphoric Acid.
Authors: Lyakhovnenko A. S. , Kolesnikova A. S. , Goncharov I. V. , Aksenova I. V. , Aksenov A. V.
Published: March 2013

Previously unknown tetraazapyrene derivatives of type (III) are prepared in a one‐pot procedure.
ChemInform Abstract: An Expeditious Synthesis of Tetrahydro‐1,2,4‐triazolo[5,1‐b]quinazolin‐8(4H)‐ones and Dihydro‐1,2,4‐triazolo[1,5‐a]pyrimidines
Authors: Kumari Kumkum , Raghuvanshi D. S. , Singh Krishna Nand
Published: March 2013

via ionic liquid‐catalyzed multi‐component reactions of 3‐aminotriazole (I) with aldehydes and dimedone or acetoacetate (V), respectively
ChemInform Abstract: An Efficient Entry to Highly Substituted Chiral 2‐Oxopiperazines from α‐Amino Acids via Iodocyclization.
Authors: Jana Amit Kumar , Das Sanjit Kumar , Panda Gautam
Published: March 2013

A strategy towards the synthesis of 2‐oxopiperazines (VII) is developed involving a convenient synthesis of the acrylic amines (VI) and their highly diastereoselective iodocyclization.
ChemInform Abstract: [3 + 3]‐Nucleophilic Addition of Acyclic Enamino Ketones to Dimethyl 1‐Aryl‐4,5‐dioxo‐4,5‐dihydro‐1H‐pyrrole‐2,3‐dicarboxylates.
Authors: Silaichev P. S. , Chudinova M. A. , Maslivets A. N.
Published: March 2013

The first example of a [3 + 3]‐nucleophilic addition of acyclic enamines to monocyclic pyrrole‐2,3‐diones (I) is described, furnishing 2,6‐diazabicyclo[3.2.1]octane derivatives (III), which are otherwise difficulty to access .
ChemInform Abstract: Stereochemistry of the Olefinic Double Bond in 13‐Membered Heterocyclic Rings Accessible by Ring‐Closing Metathesis Reaction.
Authors: Rao H. Surya Prakash , Rafi Shaik , Kumar P. Ratish , Guravaiah C. , Muthanna Nandurka
Published: March 2013

In the presence of Grubbs I catalyst, the heterocyclic rings are either obtained as exclusive (E)‐isomers or as inseparable E/Z‐mixtures.
ChemInform Abstract: Enantioselective Synthesis and Cross‐Coupling of Tertiary Propargylic Boronic Esters Using Lithiation—Borylation of Propargylic Carbamates.
Authors: Partridge Benjamin M. , Chausset‐Boissarie Laetitia , Burns Matthew , Pulis Alexander P. , Aggarwal Varinder K.
Published: March 2013

Changing from pinacol to neopentyl glycol to ethylene glycol the enantioselectivities increase.
ChemInform Abstract: Dehydrogenative Silylation of Terminal Alkynes with Hydrosilanes under Zinc—Pyridine Catalysis.
Authors: Tsuchimoto Teruhisa , Fujii Masakazu , Iketani Yoshihiko , Sekine Masaru
Published: March 2013

First time, alkynylsilanes are synthesized in excellent yields by dehydrogenative silylation of terminal alkynes with hydrosilanes.
ChemInform Abstract: Unusual Pyrrolyl 4‐Quinolinone Alkaloids from the Marine‐Derived Fungus Penicillium sp. ghq208
Authors: Gao Huquan , Zhang Lianqing , Zhu Tianjiao , Gu Qianqun , Li Dehai
Published: March 2013

isolation, structural elucidation and cytotoxicity of a new and unusual pyrrolyl 4‐quinolinone alkaloid, penicinoline E(I), and three known derivatives
ChemInform Abstract: Semi‐Synthesis and Biological Evaluation of 1,2,3‐Triazole‐Based Podophyllotoxin Congeners as Potent Antitumor Agents Inducing Apoptosis in HepG2 Cells.
Authors: Chen Lijuan , et al. et al.
Published: March 2013

Some of the new compounds, e.g. derivatives (I), exhibit approximately 100‐fold more potent inhibitory activity against four tumor cell lines (HepG2, MKN‐45, NCI‐H1993 and B16) than etoposide as positive control.
ChemInform Abstract: Butyrolactone and Cycloheptanetrione from Mangrove‐Associated Fungus Aspergillus terreus
Authors: Shen Yi , Zou Jianhua , Xie Dan , Ge Hanlin , Cao Xiuping , Dai Jungui
Published: March 2013

isolation, structure determination and cytotoxicity of new butyrolactone (I) and terretriones A—C (II)
ChemInform Abstract: Furandiones from an Endophytic Aspergillus terreus Residing in Malus halliana
Authors: Gu Wen , Qiao Chao
Published: March 2013

isolation and structure elucidation of two new furandione derivatives, asperterone B (I) and C (II), which show moderate cytotoxic activities against the human colorectal carcinoma SW1116
ChemInform Abstract: Single‐Phased Emission‐Tunable Mg‐Doped ZnO Phosphors for White LEDs.
Authors: Shi Qiang , Wang Zhenglong , Liu Yunlong , Yang Bing , Wang Guoju , Wang Wenjun , Zhang Junying
Published: March 2013

Mg‐doped ZnO phosphors are obtained from a previously described precursor gel by annealing in air at 850 °C for 3 h followed by a second annealing step in a CO reducing atmosphere at 850 °C for different times (10, 30, 60, 180, and 399 min).
ChemInform Abstract: High‐Temperature Ferromagnetism in the Super‐Dilute Magnetic Semiconductor GaN:Gd
Authors: Brandt O. , Dhar S. , Perez L. , Sapega V.
Published: March 2013

Review: 53 refs.
ChemInform Abstract: Electron Paramagnetic Resonance Spectroscopic Investigation of Manganese Doping in ZnL (L: O, S, Se, Te) Nanocrystals
Authors: Bhattacharyya Sayan , Zitoun David , Gedanken Aharon
Published: March 2013

Review: 49 refs.
ChemInform Abstract: Recent Advances in Aqueous Actinide Chemistry and Thermodynamics
Authors: Altmaier Marcus , Gaona Xavier , Fanghaenel Thomas
Published: March 2013

Review: 199 refs.
ChemInform Abstract: Complexation and Extraction of Trivalent Actinides and Lanthanides by Triazinylpyridine N‐Donor Ligands
Authors: Panak Petra J. , Geist Andreas
Published: March 2013

Review: 183 refs.
ChemInform Abstract: Paramagnetic 3d Coordination Complexes Involving Redox‐Active Tetrathiafulvalene Derivatives: An Efficient Approach to Elaborate Multi‐Properties Materials
Authors: Pointillart Fabrice , Golhen Stephane , Cador Olivier , Ouahab Lahcene
Published: March 2013

Review: 86 refs.
ChemInform Abstract: Organometallic Complexes of the Platinum Metals: Synthesis, Structure, and Catalytic Applications
Authors: Paul Piyali , Bhattacharya Samaresh
Published: March 2013

Review: 6 refs.
ChemInform Abstract: Optically Active Bis(oxazolinyl)phenyl Metal Complexes as Multipotent Catalysts
Authors: Ito Jun‐ichi , Nishiyama Hisao
Published: March 2013

Review: 72 refs.
ChemInform Abstract: The Chemistry of Pincer Complexes of 13‐15 Main Group Elements
Authors: Jambor Roman , Dostal Libor
Published: March 2013

Review: 107 refs.
ChemInform Abstract: ECE‐Type Pincer Complexes of Nickel
Authors: Zargarian Davit , Castonguay Annie , Spasyuk Denis M.
Published: March 2013

Review: 108 refs.
ChemInform Abstract: Tuning of PCP Pincer Ligand Electronic and Steric Properties
Authors: Roddick Dean M.
Published: March 2013

Review: 187 refs.
ChemInform Abstract: The Monoanionic ECE‐Pincer Ligand: A Versatile Privileged Ligand Platform — General Considerations
Authors: van Koten Gerard
Published: March 2013

Review: 84 refs.
ChemInform Abstract: Ligated Organocuprates: An A—Z Routemap of Mechanism and Application
Authors: Woodward Simon , Willcox Darren
Published: March 2013

Review: 83 refs.
ChemInform Abstract: Supramolecular Self‐Assembly of Transition Metal Carbonyl Molecules Through M—CO(Lone Pair)...π(Arene) Interactions
Authors: Zukerman‐Schpector Julio , Haiduc Ionel , Tiekink Edward R. T.
Published: March 2013

Review: 124 refs.
ChemInform Abstract: Metallabenzenes and Metallabenzenoids
Authors: Dalebrook Andrew F. , Wright L. James
Published: March 2013

Review: 126 refs.
ChemInform Abstract: Stereoselective Glycosylation of Glucosamine: The Role of the N‐Protecting Group
Authors: Enugala Ramu , Carvalho Luisa C. R. , Dias Pires Marina J. , Marques M. Manuel B.
Published: March 2013

Review: 95 refs.
ChemInform Abstract: Non‐Redox‐Metal‐Catalyzed Redox Reactions: Zinc Catalysts
Authors: Wu Xiao‐Feng
Published: March 2013

Review: 50 refs.
ChemInform Abstract: Design of Clathrate Compounds that Use Only Weak Intermolecular Attractions
Authors: Bishop Roger
Published: March 2013

Review: 77 refs.
ChemInform Abstract: DNA Glycoclusters and DNA‐Based Carbohydrate Microarrays: From Design to Applications
Authors: Morvan Francois , Vidal Sebastien , Souteyrand Eliane , Chevolot Yann , Vasseur Jean‐Jacques
Published: March 2013

Review: 174 refs.
ChemInform Abstract: Iridium(III) Complexes as Therapeutic and Bioimaging Reagents for Cellular Applications
Authors: Lo Kenneth Kam‐Wing , Zhang Kenneth Yin
Published: March 2013

Review: 124 refs.
ChemInform Abstract: Triazole: A New Motif for Anion Recognition
Authors: Haridas V. , Sahu Srikanta , Kumar P. P. Praveen , Sapala Appa Rao
Published: March 2013

Review: 73 refs.
ChemInform Abstract: Simple Tertiary Phosphines to Hexaphosphane Ligands: Syntheses, Transition Metal Chemistry and Their Catalytic Applications
Authors: Balakrisna Maravanji S. , Rao Sowmya , Choubey Bimba
Published: March 2013

Review: 76 refs.
ChemInform Abstract: Triazole‐Based One‐Dimensional Spin‐Crossover Coordination Polymers
Authors: Roubeau Olivier
Published: March 2013

Review: 158 refs.
ChemInform Abstract: Progress in Copper‐Mediated Formation of Trifluoromethylated Arenes.
Authors: Liu Tianfei , Shen Qiong
Published: March 2013

Review: 48 refs.
ChemInform Abstract: Domino Reactions Initiated by Enantioselective Cu‐Catalyzed Conjugate Addition.
Authors: Galestokova Zuzana , Sebesta Radovan
Published: March 2013

Review: 47 refs.
ChemInform Abstract: Oxidative Carbonylation as a Powerful Tool for the Direct Synthesis of Carbonylated Heterocycles
Authors: Gabriele Bartolo , Mancuso Raffaella , Salerno Giuseppe
Published: March 2013

Review: 69 refs.
ChemInform Abstract: Asymmetric Kinugasa Reaction Involving Six‐Membered Cyclic Nitrones.
Authors: Grzeszczyk Barbara , Polawska Kamila , Shaker Yasser M. , Stecko Sebastian , Mames Adam , Woznica Magdalena , Chmielewski Marek , Furman Bartlomiej
Published: March 2013

Review: 50 refs.
ChemInform Abstract: Recent Advances in Stereoselective Synthesis of 1,3‐Dienes
Authors: De Paolis Michael , Chataigner Isabelle , Maddaluno Jacques
Published: March 2013

Review: 207 refs.
ChemInform Abstract: Stereoselective Synthesis of Mono‐fluoroalkenes
Authors: Hara Shoji
Published: March 2013

Review: 102 refs.
ChemInform Abstract: Stereoselective Synthesis of Z‐Alkenes
Authors: Siau Woon‐Yew , Zhang Yao , Zhao Yu
Published: March 2013

Review: 79 refs.
ChemInform Abstract: Synthesis and Modifications of Phosphinic Dipeptide Analogues
Authors: Mucha Artur
Published: March 2013

Review: 127 refs.
ChemInform Abstract: Applications of Isocyanides in the Synthesis of Heterocycles
Authors: Akritopoulou‐Zanze Irini
Published: March 2013

Review: 211 refs.
ChemInform Abstract: Isocyanide‐Based Multicomponent Reactions Towards Benzodiazepines
Authors: Huang Yijun , Domling Alexander
Published: March 2013

Review: 46 refs.
ChemInform Abstract: 2,3‐Bis(phenylsulfonyl)‐1,3‐butadiene‐mediated Syntheses of Piperidone Derivatives
Authors: Flick Andrew C. , Padwa Albert
Published: March 2013

Review: 150 refs.
ChemInform Abstract: Synthesis of Pyrroles and Their Derivatives from Isocyanides
Authors: Ono Noboru , Okujima Tetsuo
Published: March 2013

Review: 192 refs.
ChemInform Abstract: Marine Natural Products
Authors: Blunt John W. , Copp Brent R. , Keyzers Robert A. , Munro Murray H. G. , Prinsep Michele R.
Published: March 2013

Review: 870 refs.
ChemInform Abstract: Tetraethylammonium Tetraselenotungstate: A Versatile Selenium Transfer Reagent in Organic Synthesis
Authors: Sureshkumar Devarajulu , Gopinath Purushothaman , Chandrasekaran Srinivasan
Published: March 2013

Review: 77 refs.
ChemInform Abstract: Recent Developments on Domino Metathesis Reactions in India
Authors: Nandurdikar Rahul S. , Kaliappan Krishna P.
Published: March 2013

Review: 77 refs.
ChemInform Abstract: Applications of Isocyanides in IMCRs for the Rapid Generation of Molecular Diversity
Authors: Ayaz Muhammad , De Moliner Fabio , Dietrich Justin , Hulme Christopher
Published: March 2013

Review: 151 refs.
ChemInform Abstract: Amine (Imine) Component Surrogates in the Ugi Reaction and Related Isocyanide‐Based Multicomponent Reactions
Authors: Krasavin Mikhail
Published: March 2013

Review: 75 refs.
ChemInform Abstract: Synthetic Application of Isocyanoacetic Acid Derivatives
Authors: Gulevich Anton V. , Zhdanko Alexander G. , Orru Romano V. A. , Nenajdenko Valentine G.
Published: March 2013

Review: 263 refs.
ChemInform Abstract: Chiral Non‐racemic Isocyanides
Authors: Banfi Luca , Basso Andrea , Riva Renata
Published: March 2013

Review: 123 refs.
ChemInform Abstract: Recent Advances in Catalysis by Water‐Soluble Metalloporphyrins
Authors: Simonneaux Gerard , Le Maux Paul , Chevance Soizic , Srour Hassan
Published: March 2013

Review: 188 refs.
ChemInform Abstract: Metalloporphyrin‐catalyzed C‐C Bond Formation
Authors: Zhou Cong‐Ying , Lo Vanessa Kar‐Yan , Che Chi‐Ming
Published: March 2013

Review: 126 refs.
ChemInform Abstract: The Chemistry and Biology of β‐Thiolactones
Authors: Noel Amandine , Delpech Bernard , Crich David
Published: March 2013

Review: 124 refs.
ChemInform Abstract: Synthetic Strategies for the Biotinylation of Bioactive Small Molecules
Authors: Trippier Paul C.
Published: March 2013

Review: about 100 refs.
ChemInform Abstract: Analysis, Optimization, and Control of Solid‐Oxide Fuel Cell Systems
Authors: Braun Robert J. , Vincent Tyrone L. , Zhu Huayang , Kee Robert J.
Published: March 2013

Review: 95 refs.
ChemInform Abstract: Nuclear Quadrupole Resonance Spectroscopy
Authors: Dillon K. B.
Published: March 2013

Review: 59 refs.
ChemInform Abstract: Conformational Study of Peptoids
Authors: De Santis Emiliana , Edwards Alison A.
Published: March 2013

Review: 35 refs.
ChemInform Abstract: Recent Advances in Imaging and Monitoring of Heterogeneous Catalysts with Raman Spectroscopy
Authors: Calvino‐Casilda Vanesa , Banares Miguel A.
Published: March 2013

Review: 197 refs.
Relational Demography in Supervisor‐Subordinate Dyads: An Examination of Discrimination and Exclusionary Treatment
Authors: Schaffer Bryan S. , Riordan Christine M.
Published: March 2013

This study examines the link between supervisor‐subordinate dissimilarity and associated perceptions of discrimination and exclusionary treatment. Using a sample of 1,059 employees from a large Southeastern insurance company, we examined age, race, and gender dissimilarity as predictors of perceived discrimination, supervisory support, and leader‐member exchange. In addition, we examined supervisor liking/attraction and status of affiliation with supervisor as intervening variables. Race dissimilarity related positively to perceptions of discrimination and exclusionary treatment, mediated by both supervisor liking and status. Effects for age and gender dissimilarity were nonsignificant. We discuss the importance of these findings for understanding and managing dyadic relationships at work. Copyright © 2013 ASAC. Published by John Wiley & Sons, Ltd.
Capacité d'apprentissage organisationnel : analyse théorique et étude empirique dans le contexte des équipes de projets d'aide publique au développement
Authors: Mbengue Ababacar , Sané Seydou
Published: March 2013

Although several studies have investigated Organizational Learning Capability (OLC), the question of its operationalization remains open. We review the OLC concept, analyze its relationship to Organizational Learning (OL), and assess the validity of its operationalization through three models (formative, reflexive, mixed). While part of the literature states that OLC has five dimensions (experimentation, risk taking, dialogue, interaction with stakeholders, and participation in decision making), our exploratory study of 41 Official Development Aid projects suggests the existence of an important sixth dimension for OLC: autonomy vis‐à‐vis the national supervisor. The theoretical and practical implications of this finding are then discussed. Copyright © 2013 ASAC. Published by John Wiley & Sons, Ltd.
Effect of Ritonavir‐Boosted Danoprevir, a Potent Hepatitis C Virus Protease Inhibitor, on QTc Interval in Healthy Subjects: Results from a Thorough QT Study
Authors: Morcos Peter N. , Kulkarni Rohit , Scoon Sally , Smith Patrick F. , Brennan Barbara J.
Published: March 2013

Preclinical Research

Danoprevir is a macrocyclic hepatitis C virus protease inhibitor in clinical development in combination with ritonavir. This study investigated whether ritonavir‐boosted danoprevir (DNVr) affects cardiac repolarization, as measured by study‐specific corrected QT (QTcS) interval. This was a single‐center, single‐dose, randomized, double‐blind, double‐dummy, four‐way crossover study. Healthy subjects received a single dose of each treatment (therapeutic‐dose DNVr 100/100 mg; supratherapeutic‐dose DNVr 400/100 mg; positive control [moxifloxacin 400 mg]; placebo) by randomized sequence, at least 7 days apart. Triplicate readings by continuous Holter 12‐lead digital electrocardiogram (Mortara Instruments, Inc., Milwaukee, WI) were obtained during day 1 and 24 h postdose. There was no clinically relevant increase in QTcS interval with DNVr compared with placebo in 52 subjects. The upper one‐sided 95% confidence interval for placebo‐subtracted change from baseline QTcS was <10 ms at all time points for both DNVr doses. Pronounced increase in QTcS with moxifloxacin treatment confirmed the ECG assay sensitivity. There was no trend for a concentration‐dependent effect of danoprevir on QTcS. DNVr doses were well tolerated. This thorough QTc study demonstrates no clinically or statistically significant effect on cardiac repolarization with administration of a single dose of danoprevir (up to 400 mg) with low‐dose ritonavir (100 mg) in healthy subjects.