bluuebunny/crossref_metadata_2025 huggingface dataset:
Antioxidant and enzyme inhibition activities of Spartium junceum with HPLC-DAD profiling
Authors: Eruygur Nuraniye , Ayaz Fatma , Ayyildiz Hamide Filiz , Bağci Yavuz
Published: September 2022

Spartium junceum L., a Fabaceae plant, is commonly known as Spanish broom and cultivated in the Mediterranean regions. This study aimed to investigate the chemical profiles and antioxidant and different enzyme inhibitory activities of methanol, ethanol and aqueous extracts obtained from flowers and stems of S. junceum. Also, their phenolic compositions were analyzed by high-performance liquid chromatography with a diode-array detector (HPLC-DAD). The aqueous extract of stems showed the highest phenolic content (63.94 mg gallic acid equivalents/g), while the aqueous extract of stems contained the highest flavonoid content (61.33 mg quercetin equivalents/g). The stem water extract demonstrated the highest 2,2′-diphenyl-1-picrylhydrazyl radical-scavenging activity (IC50: 2327 μg/ml), while the stem water extract exhibited a strong 2,2′-azino-di(3-ethylbenzothiazoline-6-sulfonic acid) radical-scavenging activity (IC50: 91.80 ± 0.90 μg/ml). The tested extracts differed greatly in terms of enzyme inhibition activity. The stem water extract showed the highest anti-acetylcholinesterase activity (IC50: 46.69 ± 1.66 μg/ml); however, the stem methanol extract exhibited a strong anti-butyrylcholinesterase activity (IC50: 76.39 ± 0.27 μg/ml). The flower methanol extract was the most active against the α-glucosidase enzyme (IC50: 296.7 ± 3.77 μg/ml). All extracts showed low activities against α-amylase and tyrosinase enzymes. The evaluation of the biological activity results provides evidence for bioactivity-guided isolation studies on the active extracts of this plant.
Terapia cognitiva para adolescentes em liberdade assistida: um relato de experiência
Authors: Vidal Júlia Luciane , Piccoloto Luciane Benvegnú , Schott Fabiane , Pasche Alice Dias
Published: September 2022

Esse artigo apresenta um relato de experiência da atuação acadêmica-profissional, que ocorreu no Centro de Defesa dos Direitos da Criança e do Adolescente – CEDEDICA, em Santa Maria/RS. Objetivou-se identificar os fatores que influenciaram o cometimento do ato infracional, e discorrer sobre os atendimentos psicológicos realizados com base na terapia cognitivo-comportamental, para os adolescentes em cumprimento de medida socioeducativa em meio aberto, de liberdade assistida. A pesquisa teve cunho qualitativo, a qual proporcionou a descoberta dos processos sociais e psicológicos ainda pouco conhecidos sobre o grupo específico, a partir de observações e da realização dos atendimentos semanais, entre o período de agosto de 2017 e junho de 2018. Os resultados apontaram que a prática do ato infracional pode ser influenciada por fatores como desigualdade social, família desestruturada, baixa escolaridade, falta de oportunidade e baixas expectativas no mercado de trabalho, criminalidade, assim como, a própria fase da adolescência. Através da terapia cognitivo-comportamental pode-se identificar e modificar as crenças desses adolescentes. Por fim, obteve-se uma mudança de pensamento e comportamento dos adolescentes, assim como, maior capacidade de expressão verbal e emocional.
Saúde mental da comunidade universitária na pós-pandemia: desafios e perspectivas
Authors: Sunde Rosário Martinho
Published: September 2022

Este é um estudo de revisão integrativa da literatura cujo obetivo foi avaliar os impactos psicológicos da pandemia da Covid-19 na comunidade universitária e perspectivar medidas de enfrentamento no pós-pandemia. A busca dos estudos ocorreu durante o mês de outubro de 2021 em quatro bases (Science Direct, PubMed, BVS e PsycInfo) usando os seguintes descritores: “Mental health AND University OR College AND Post-pandemic”, todos consultados no dicionário de descritores na área da saúde MeSH da base de dados PubMed e Thesaurus, da PsycINFO.  Na busca inicial, foram achados cerca de 600 artigos que depois do processo de inclusão e exclusão, sobraram sete estudos, adicionados com outros cinco, achados a partir da busca manual, somando 12 artigos que foram explorados na íntegra para análise final, sob a perspectiva qualitativa de análise de conteúdo. Percebemos que a pandemia da Covid-19 afetou imensamente a saúde mental da comunidade universitária. Os comportamentos de riscos à saúde mental (medo de contaminação pelo vírus, a incerteza sobre o fim da pandemia e o retorno das aulas presenciais, medidas de distanciamento social prolongado, ansiedade e outros desconfortos psicológicos) foram notáveis entre estudantes, professores e toda comunidade acadêmica, agravados pela falta de serviços de apoio psicossocial. As universidades são desafiadas a encontrar mecanismos de promoção de serviços de apoio psicossocial da comunidade sendo prioritária no período após a pandemia.
Violência contra as mulheres e Teoria das Representações Sociais: revisão integrativa
Authors: Leal Pacheco Maria Luiza , Rubio Roso Adriane , Gudolle de Souza Janine , Souza Ana Flavia
Published: September 2022

A violência contra as mulheres é um fenômeno complexo e multicausal e seu combate vem sendo pauta do movimento feminista há pelo menos três décadas. A violência tem sido correlacionada com as maneiras como as mulheres são representadas socialmente. Uma das teorias que tem contribuído nesta direção é a Teoria das Representações Sociais (TRS). O objetivo deste artigo é compreender como a TRS está sendo articulada para o entendimento acerca de situações que envolvem violência contra as mulheres. Especificamente, o propósito foi identificar como as relações de poder/opressão são registradas nos estudos analisados de modo a entender as violências. A pergunta central que move este estudo é como certas representações sociais podem estar contribuindo para o engendramento da violência contra as mulheres. Foi realizada uma revisão integrativa, pesquisando o Portal de Periódicos da CAPES e a Biblioteca Científica Online Scielo. Após os critérios de inclusão e exclusão, foram analisados 21 artigos. Os resultados obtidos mostram que todos os artigos realizaram pesquisa qualitativa e a maioria foi publicada entre 2015 e 2018. A área de estudo dos artigos é majoritariamente da Enfermagem. O autor mais citado foi Serge Moscovici, seguido de Celso Pereira de Sá e Jean Claude Abric. Conclui-se que, apesar da teoria ser citada nos artigos, em muitos casos, o desenvolvimento das análises não aproveitam os constructos da teoria no seu potencial.
Intervenções em Desenvolvimento de Habilidades Sociais no Transtorno do Espectro Autista
Authors: Maforte Moreno Igor Felipe , Dal Bello Maria José , Bartholomeu Daniel , Vianna Soares Garcia Fernanda Helena , Tavares Wanessa , Couto Gleiber
Published: September 2022

O Transtorno do Espectro Autista (TEA), segundo a American Psychiatric Association (APA), é uma desordem do neurodesenvolvimento com início precoce e curso crônico, não degenerativo. De acordo com a Organização Mundial da Saúde (OMS), uma a cada 160 crianças possuem o transtorno. A proposta deste trabalho é uma revisão de literatura a respeito da eficácia das intervenções nas habilidades sociais em pessoas com o TEA. Para a realização da pesquisa foram utilizadas as bases de dados PEPSIC, SCIELO, Google Acadêmico, BVS, BIREME e CAPES. Ao todo foram selecionados 25 artigos, nacionais, no período de 2006 a 2020. As palavras-chave utilizadas para a busca foram “autismo”, “teoria da mente”, “habilidades sociais”, “análise do comportamento aplicada” e “ABA”. Artigos repetidos e que não possuíssem as variáveis procuradas foram excluídos. Como resultados foram encontrados dados de eficácia das intervenções descritas no aumento de habilidades sociais e variáveis relacionadas a elas. Estudos sobre a ABA e a Musicoterapia foram os mais publicados, além de terem apresentado os melhores resultados quando aplicadas em pessoas com o transtorno. Para o autismo e Teoria da Mente, foram encontrados majoritariamente dados sobre conceituação e definição. Para intervenções em ABA e musicoterapia, foram achados mais dados sobre pesquisa e prática.
A new middle Pleistocene small vertebrate fauna from the Nagyharsány Crystal Cave (Villány Hills, Southern Hungary)
Authors: Pazonyi Piroska , Szentesi Zoltán , Trembeczki Mária , Hír János , Mészáros Lukács
Published: September 2022

The Nagyharsány Crystal Cave in the Villány Hills (Southern Hungary) has yielded a very rich assemblage of small vertebrate material, mainly consisting of isolated frog bones. Th e systematic collection involved sampling from several levels in three diff erent sites. During the detailed taxonomic processing of the vertebrate material, a total of 78 taxa were identifi ed. In addition to the rich herpetofauna, birds as well as small and large mammal remains were found. Preliminary palaeoecological studies have also been carried out on material from Site I. Th e small vertebrates of the lower levels indicate a warmer, moister, and more closed environment. Towards the top of the series, this gradually changes to a cooler, drier, more open one. Th e taxonomic, allometric, and palaeoecological results also allowed the stratigraphic position of the sites to be determined. We found that the material from the Nagyharsány Crystal Cave is most resembling to the material from the MIS 11 sites of the Vár Cave (Budapest). With 3 figures and 3 tables.
Middle Eocene (Bartonian) brachiopods from Turnu Roșu (Transylvanian Basin, Romania): oldest record of Megerlia and Kraussinidae
Authors: Dulai Alfréd , Trif Nicolae , Bălc Ramona
Published: September 2022

Nannoplankton studies of the Transylvanian Turnu Roșu section, based on the presence of Reticulofenestra umbilicus, R. bisecta, R. lockeri, Helicosphaera compacta and Sphenolithus spiniger refer to Bartonian (middle Eocene) age. Th e brachiopod assemblage of Turnu Roșu contains four species. Th e assemblage is dominated by Gryphus kickxii, one of the most common brachiopod species of the European Eocene. Th e other three taxa are very rare (1–1 specimen). Terebratulina tenuistriata is also widespread in the Tethyan Eocene, while the genus Megerlia everywhere belongs to the very rare elements in the Paleogene. Th e fourth taxon is an unidentifi able fragmentary terebratulide which is clearly diff erent from the previously mentioned three taxa. Th e Bartonian Megerlia sp. specimen is the oldest known fossil record of the genus Megerlia and the family Kraussinidae. With 41 figures.
Middle Miocene Buccinoidea (Neogastropoda) assemblage from the Făget Basin (Romania) in the collection of the Hungarian Natural History Museum, Budapest
Authors: Kovács Zoltán
Published: September 2022

An early Badenian (middle Miocene) Buccinoidea (Colubrariidae, Eosiphonidae, Tudiclidae, Fasciolariidae, Melongenidae, Pisaniidae and genus Euthriofusus) assemblage – that was collected from Coşteiu de Sus, Lăpugiu de Sus, and Nemeşeşti (W Romania), and stored in the collection of the Hungarian Natural History Museum, Budapest – is revisited. Fasciolaria moravica Hoernes et Auinger, 1890 is considered as a junior synonym of Turrilatirus patruelis (Bellardi, 1884) new comb. Other new combinations: Cumia deshayesi (Michelotti, 1847) new comb., Eosipho hoernesi (Bellardi, 1872) new comb., Pseudolatirus rothi (Beyrich, 1856) new comb., Aplus lapugyensis (Hoernes et Auinger, 1890) new comb., Aplus transsylvanicus (Hoernes et Auinger, 1890) new comb. Pseudolatirus boettgeri is a new name for Fusus sublamellosus Boettger, 1906. Neotype is designated for Aptyxis palatina (Strausz, 1954). With 100 figures.
THE IMPACT OF COVID-19 INFECTION AND TREATMENT ON MIGRAINE DISABILITY AND PAIN SCORES
Authors: ÖZŞİMŞEK Ahmet , YULUG Burak , ÖKTEM Ece Özdemir , ÇANKAYA Şeyda , DURAN Umut
Published: September 2022

Aim: This study aimed to investigate the effects of favipravir used for treating Covid-19 infection and other infectious diseases, on migraine severity and frequency through VAS (Visual Analog Scale), MIDAS (Migraine Disability Assesment Scale). Methods: The study was planned retrospectively, from January 2020 to September 2021, to evaluate patient demographical features who have received migraine diagnosis before or after Covid-19 infection (3 months) admitted in the neurology outpatient clinics of Alanya Alaaddin Keykubat University Training and Research Hospital. Findings: From 70 patients in total 12 (17.1%) of the patients involved in the study were male, while 58 (82.9%) were female. 32 (45.7%) of patients used favipravir and 38 (54.3%) did not use Favipravir. The number of migraine attacks after Covid-19 were found significantly lower than the average of the VAS and Midas scores before covid infection. The average number of migraines before Covid-19 infection was 4.31 ± 2.80, which was found as 3.54 ± 3.07 after the Covid-19 infection. The effect of favipravir use on headache parameters before Covid-19 and after Covid-19 for patients were found similar (p> 0.05). Conclusion: Our study, provides valuable data on the effects of infection and/or isolation on migraine frequency and severity, possibly exerting a prophylactic effect for migraine type headaches.
GENDER ATTITUDES IN UNIVERSITY STUDENTS AND ITS AFFECTING FACTORS: ALANYA EXAMPLE
Authors: DEMİR Yaşar , DAĞ Erhan , KARAKUŞ Pınar , ÖZPINAR Saliha
Published: September 2022

Aim: The aim of this study is to determine the gender attitudes and determinants of university students. Method:Personal presentation form and gender relations scale were used to collect the data of the cross-sectional study. The universe of the study consists of undergraduate students studying at a university in Alanya in 2021-2022. Percentage, frequency, mean and multiple regression analysis were used in the analysis of the collected data. Before starting the research, permission was obtained from the ethics committee of the university where the research would be conducted. Results: 55% of the research group was female, and the age distribution was 20.85±1.25 (18-24). It was determined that the gender relations scale was affected by gender, class, department, father's education status and dating relationship, the equality sub-dimension was affected by gender, class, father's education level and family type, and the power sub-dimension was affected by gender, department, father's education level and family type.Conclusion: It was found that the gender attitudes of university students are egalitarian and affected by factors such as gender, class, department, father's education level and dating relationship. Considering that universities are places where the development and transformation of society is experienced, it can be suggested to reveal the general attitude of university students by conducting such studies in different universities.
EXAMINATION OF LIFE SATISFACTION LEVELS OF SPORTS SCIENCES FACULTY STUDENTS AT HOME DURING THE PANDEMIC PROCESS (FIRAT UNIVERSITY EXAMPLE)
Authors: TAN Çetin , ORHAN Ebru , YÜCEL Ali Serdar , YAVUZ Cumaali
Published: September 2022

Aim: In this study, it is aimed to examine the life satisfaction levels of the students of the faculty of sports sciences during the pandemic process. In addition to the stated purpose, there is a significant difference in terms of gender, age, marital status, place of residence, department of education, class, parent education status and parental coexistence and number of people living together among students' levels of satisfaction with life at home during the pandemic process. It is also aimed to determine whether In the research, the scanning model, which is included in the quantitative research designs, was used as a method. The universe of the research The universe of the research consists of students studying at the Faculty of Sports Sciences of Fırat University in the 2021-2022 academic year. The sample of the study consists of 534 students who were randomly selected from the population and participated voluntarily. While the "Personal Information Form" consisting of 13 questions was used to determine the personal information of the students as a data collection tool in the research, the "Life Satisfaction at Home During the Global Epidemic (Covid-19) Process" scale was used to determine the level of life satisfaction of the students at home during the pandemic process. The research data collected with the specified data collection tools were analyzed by using Independent Samples t-Test and One-Way Analysis of Variance, together with descriptive statistical methods, due to their normal distribution. In the study, it was determined that the students of the faculty of sports sciences were above the average at home life satisfaction during the pandemic process. This result was evaluated as the students were happy to be at home during the pandemic process. In addition, in the study, it was determined that the level of satisfaction with life at home of the students of the faculty of sports sciences during the pandemic period differed significantly according to the variables of gender, marital status, age and place of residence.
SENSATIONS IN URBAN SPACE: SENSATIONAL ANALYSIS OF THE YELDEĞİRMENİ AREA
Authors: TAPKI Sinem
Published: September 2022

Aim: This research aims to examine the forms and features of understanding and grasping urban space through the senses. In the study, unlike the eye-centred paradigm, it discusses the importance of understanding urban space, not only with the sense of sight, but also with other senses, and its importance in making sense of it. Method: Between January and September 2021, Kadıköy Yeldeğirmeni, Rıhtım Avenue, Karakolhane Street and İskele Street were experienced and sensory analysis of these experienced axes was made.The sensations felt were evaluated using graphical expression in the computer environment. During the sensory analysis, no instrument was used to measure the intensity of the sensations, and the experiencing body was taken as the basis. The scale showing the intensity of the sensations is subjective, and the interval regions in the diagrams are not a mathematical value, but the experienced area. Results: According to the sensory analysis, the sensations and dominant sensations on the three axes differ. The factors that create each sensation are also different. It was determined that sound, motion and visual sensations were dominant in İskele Street, sound sensation in Rıhtım Street, and sound and smell sensation in Karakolhane Street. In this study, in which the eye-centred paradigm was questioned, it was noted that urban space can be grasped with multi-sensational perception. Although visual sense is dominant today, urban experiences consist of the sum of sight, smell, sound, muscle-balance and touch senses. The fact that visuality comes to the fore in the representation of sensations also shows the need for new studies to be done.
USING GEORADAR (GPR) IN DETECTION OF GROUND PROBLEMS: DIYARBAKIR İSKENDER PASHA TOMBS
Authors: IŞIK Nursen , HALİFEOĞLU Fatma Meral , İPEK Süleyman , POLAT Mücahit
Published: September 2022

Aim: This study was carried out in order to determine the causes of structural problems and damages due to the ground in the tombs of Iskender Pasha Mosque. Method: Georadar (GPR) surveys were carried out by expert geophysical engineers to determine the location and level of soil-related structural problems and damages in two tombs located southeast of the Iskender Pasha Mosque. In georadar scans, Python-3 GPR device and 100 Mhz and 1.8 Ghz antenna were used. In georadar (GPR) measurement studies, data processing steps were followed and Reflex W (Sandmeier, 2003:31) program was used for these operations. Results: Structural problems, which were determined observationally by fieldwork in the tombs of İskender Pasha Mosque, were instrumentally supported by georadar (GPR) scans. As a result of the scans, voids, collapses and flooded areas on the tomb floors and their locations were determined. Conclusion: In this study, the locations and damage levels of the structural problems on the floors of the two tombs located southeast of the Iskender Pasha Mosque were determined by georadar (GPR) surveys. In the scans, it has been determined that there are subsidence deformations and areas that receive water in the first (1) and second (2) tombs, and the locations and levels of damage and deformations are shown with radargram sections. The study was completed by presenting suggestions for the structural problems that occurred in the tombs where ground surveys were made.
THE RESEARCH OF SAKARYA/ HENDEK URBAN TRANSFORMATION APPLICATION WITH URBAN MORPHOLOGY APPROACH
Authors: TANRIVERDİ KAYA Ayşegül , KUTLU Serpil
Published: September 2022

Aim: Turkey is a country with high disaster risk and rapid urbanization increase the seismic risk in certain regions. Therefore, urban transformation projects have come to the agenda as a solution in our country in recent years. This study is a research that aims to manage the transformation process with the urban morphology approach by considering the place-context morphologically, which is generally ignored in urban transformation projects. Method: In the field study, spatial analyzes were made by comparing the morphological parameters such as street pattern, building-density relationship, use of open green space, and building island patterns before and after the intervention. Findings: As a result of the analysis, it has been seen that the street and permeable urban fabric has deteriorated, thus the stratification of private and public spaces is eliminated, with the combination of parcels and building blocks to obtain a single building block. It has been observed that the human scale has been damaged by the increasing densities, which have resulted from mass growth. Conclusion: Space is a phenomenon produced by society. We can make inferences from morphological parameters in order to understand this phenomenon and use it as data in urban transformation applications.
EVALUACIÓN DE TRATAMIENTOS DE Q&P SOBRE ACEROS FUNDIDOS MEDIO CARBONO-ALTO SILICIO
Authors: Oyola María José , Aristizábal Ricardo , Ríos Óscar
Published: September 2022

Se investigó la influencia de los patrones de segregación sobre las transformaciones en estado sólido obtenidas a partir de un tratamiento de Q&P, realizado en un acero fundido con 0.52% de C, aleado con Cr, Mn y Si. El esquema de tres tratamientos térmicos fue llevado a cabo partiendo de la austenización total de las muestras a 900°C, seguido por un temple QT=250 y una partición (PT)= 270°C, 300°C y 350°C. Posteriormente, se llevó a cabo la caracterización microestructural de las muestras tratadas con Q&P mediante microscopía óptica (MO) y microscopía electrónica de barrido (SEM), en conjunto con un análisis de difracción de rayos X (DRX) con el cual se cuantificó un nivel máximo de 19% de austenita retenida. Finalmente, se analizó la microsegregación de los elementos sustitucionales empleando espectroscopía de rayos X de energía dispersiva (SEM-EDX), con lo que se estableció la relación entre la composición química de las primeras zonas en solidificar (FTF) y las últimas zonas en solidificar (LTF), con la microestructura observada y la microdureza medida sobre cada región.
FUSIÓN LÁSER EN CAMA DE POLVOS DE UN VIDRIO METÁLICO BASE HIERRO: ESTUDIO EXPLORATORIO
Authors: Henao Penenrey John Dairo
Published: September 2022

Actualmente, la fabricación de componentes volumétricos a partir de vidrios metálicos y/o aleaciones fuera del equilibrio es un reto debido a las condiciones de enfriamiento requeridas para obtener un estado amorfo completo y/o un conjunto de fases en particular. Algunas tecnologías de fabricación aditiva, como la sinterización directa de metal por láser (DMLS), pueden ofrecer una alternativa para la fabricación de componentes de vidrio metálico a partir de polvos de materia prima 100 % amorfos. El principal desafío cuando estos materiales se procesan mediante fabricación aditiva es mantener el contenido amorfo del polvo inicial en las piezas finales. En el presente trabajo, se empleó un vidrio metálico comercial con hierro como su elemento principal, con el fin de realizar un estudio exploratorio de la influencia de los principales parámetros del proceso DMLS sobre la capacidad de este material para formar piezas consolidadas por este proceso. Los parámetros estudiados aquí fueron la potencia del láser, la velocidad de escaneo y la densidad de energía volumétrica. Se empleó la técnica de difracción de rayos X para realizar la caracterización de las fases obtenidas en las piezas fabricadas. Los resultados del estudio sugieren que la fabricación de piezas con el material estudiado es posible, pero existe un rango de densidades de energía aplicadas por el láser durante el proceso dentro de los que se favorece la formación de las piezas.
COMPACTED ADOBES FROM GRAVEL AND SAND WASH MUDS OF AN AGGREGATES PLANT AS WASTES VALORIZATION STRATEGY
Authors: Cabrera Poloche Francisco Dario , Restrepo Baena Oscar Jaime , Tobón Jorge Iván , Escudero Restrepo Sergio , Álvarez Zuluaga Stephanie
Published: September 2022

Fine waste management from quarry has been commonly the final disposal in mining tailings and as refilling material for landscape recovery in areas already exploited. However, different uses of these wastes have been studied, highlighting the earth constructions because a new economic benefit is generated and the environmental impact is reduced. Moreover, compared to cement constructions, the earth constructions are environmentally friendly and represent an energy saving, due to their low emission of CO2 by low or no-cement content in their manufacture in contrast to good physical and mechanical properties obtained. So, in this work, the use of wastes muds from an aggregates plant (as result of crushing and washing process) were evaluated as a circular economy strategy. Raw materials were chemical, mineralogical and physically characterized and were employed in the elaboration of cubic specimens of un-calcined material, which they were hydraulically compacted in metal molds at mixtures of wastes muds, commercial gray cement and washed fine sand. The cubic specimen’s performance was evaluated by Simple Compressive Strength (SCS) and water absorption test. In the best of configurations, an increase in SCS of 221.3% (reaching 8 MPa) on samples of 20% cement with respect to samples of only waste was found and, in turn, an increase of 517.3% (reaching 15 MPa) when these were cured in water was also found. Thus, wastes mixed with small amounts of cement are promising in the Manufacture of Compacted Adobes (MCA), particularly as masonry or structural elements made of un-calcined wastes.
Diabetes mellitus y COVID-19, ¿una relación bidireccional?
Authors: Gómez Susana , Pineda-Trujillo Nicolás , Pereira-Gomez María del Pilar , Sarmiento-Ramón María Paula
Published: September 2022

La pandemia por COVID-19 ha generado una emergencia de salud pública en todo el mundo. El riesgo, la gravedad y la mortalidad de la enfermedad se han asociado a enfermedades crónicas no transmisibles, como la diabetes mellitus tipo 1 y 2. Se ha planteado la posibilidad de una relación bidireccional entre estas dos entidades y son múltiples las explicaciones fisiopatológicas que las relacionan. Por un lado, la mayoría de los estudios concuerdan en que la disglucemia se asocia a un desenlace negativo de la infección. Además, el COVID-19 puede provocar un empeoramiento del control glucémico y ser un factor desencadenante para el desarrollo de diabetes mellitus tipo 1.
Validation of an outdoor efficiency model for photovoltaic modules
Authors: Murillo-Soto Luis Diego , Meza-Benavides Carlos
Published: September 2022

The study of the efficiency of photovoltaic modules in outdoor conditions allows determining their correct operation and to detect abnormal behavior. Most efficiency models developed use experimental data that are difficult to obtain as they require specialized equipment and a long measurement time under laboratory conditions to identify or adjust the model parameters. In this article, we propose a linear equation that estimates the efficiency of photovoltaic modules using irradiance and back panel temperatura measurements as input variables. The main contribution is that the parameters of the proposed model can be obtained directly from the reference information (IEC61853-1 power values) without any data regression. The proposed model was validated using experimental data obtained from three different climatic zones during a whole year. The model shows the best fit to the data of four analyzed models, and its normalized root mean square deviation for all photovoltaic modules is less than 3.6%; this dispersion could be explained by the fact that the outdoor data have an uncertainty of around 3.0%
Concepts and features of special administrative and legal regimes in Ukraine
Authors:   Ivan Chernyakhovsky National Defense University of Ukraine, Stupak D.
Published: September 2022

The concept and features of special administrative and legal regimes in Ukraine are studied. It is established that special administrative and legal regimes occupy a special place in the system of legal regimes. The peculiarity is that they belong to the field of public safety, national security and national interests, as well as the use of special legal instruments such as granting exclusive powers to public authorities, the possibility of restricting the rights and freedoms of man and citizen and others. It is established that these features include special administrative and legal regimes mostly in the field of administrative law, as the achievement of the goals of their implementation is carried out through the formation of a system of "rigid" public (administrative) management. Researchers' views on the concept of special administrative and legal regimes and their features are studied. It is established that their diversity is justified by the difference in the conditions under which a particular administrative-legal regime is introduced, in particular the purpose of implementation, the type of crisis situation, the subjects of ensuring the implementation of the regimes under consideration, etc. The basic features of special administrative and legal regimes, regardless of their type and conditions of implementation, are highlighted. The author's definition of the special administrative-legal regime as the special order of legal regulation established by administrative-legal norms which is introduced for the purpose of prevention or elimination of threats to national interests and national security with granting to subjects of maintenance of the special legal regime of special powers implementation, measures, including restrictions on human and civil rights and legitimate interests of legal entities within certain space and time limits.
Structural and functional features of the heart and the dynamics of biomarkers in the progression of chronic heart failure with a moderately reduced ejection fraction of the left ventricle in patients with diabetes mellitus
Authors: Efremova Liudmila S. , Vasilieva Lyudmila V. , Gosteva Elena V.
Published: September 2022

Aim. To study the relationship between serum levels of aldosterone, tissue inhibitor of matrix metalloproteinases-1 (TIMP-1), tumor necrosis factor-alpha (TNF-) and structural and functional changes in the heart during the progression of chronic heart failure (CHF) with a moderately reduced ejection fraction (CHFunEF) in patients with type 2 diabetes mellitus (DM).
Material and methods. 58 patients were examined 30 (51.7%) men and 28 (48.3%) women diagnosed with DM and CHFunEF (EF=4149%), with functional class (FC) I, II and III of CHF according to New York Heart Association (NYHA). The control group consisted of 16 people. Patients underwent echocardiography, determination of serum levels of aldosterone, TIMP-1 and TNF- by ELISA. The patients were divided into 2 groups: 1st group patients with DM and CHFunEF who had a myocardial infarction (MI) 27 people (46.6%), 2nd group patients with DM and CHFunEF 31 people (53.4%). Statistica v. 10.0 software (USA) was used for statistical analysis. Differences were considered statistically significant at р0.05.
Results. Serum levels of aldosterone, TIMP-1 and TNF- were significantly higher than those of the control group and increased with an increase in CHF FC. In patients of the 1st group, the volume and index values of the left parts of the heart and serum levels of biomarkers significantly exceeded those of the 2nd group.
Conclusion. Activation of the aldosterone system, increased profibrotic and immuno-inflammatory processes with the progression of CHFunEF in patients with DM lead to an increase in serum levels of aldosterone, TIMP-1 and TNF- with an increase in CHF FC. Patients with DM and CHFunEF who have undergone MI have more pronounced structural and functional changes in the heart and greater values of volumetric and index parameters of the left heart than patients with DM and CHFunEF. Serum levels of aldosterone, TIMP-1 and TNF- in patients with DM and CHFunEF who have undergone MI exceed those in patients with DM and CHFunEF, these biomarkers can be used to diagnose the progression of CHFunEF in patients with DM.
Associative role of polymorphism of the gene of MMP-9 (rs11697325) in development of arterial hypertension in patients with the rheumatoid arthritis
Authors: Nikulina Svetlana Yu. , Chernova Anna A. , Tolstokorova Yuliya A. , Varavko Yulia O.
Published: September 2022

Aim. To study a contribution of polymorphism A-8202G (rs11697325) of a gene of matrix metalloproteinase-9 (MMP-9) in development of arterial hypertension (AH) in patients with the rheumatoid arthritis (RA).
Materail and methods. 143 patients with RA were examined, among which a group of patients with RA without AH (n=50) and a group of patients with RA in association with AH (n=93) were identified. Healthy volunteers (n=151) were also divided into 2 groups comparable in age, sex and number with the main groups (control group 1 n=54, control group 2 n=97). The work used a range of clinical, laboratory, instrumental methods. A molecular genetic study was also performed. Blood samples were taken from all study participants. DNA isolation was carried out by the standard phenol-chloroform method. Genotyping for the MMP-9 gene was performed by PCR-RFLP analysis (polymerase chain reaction restriction fragment length polymorphism). PCR was carried out with a set of primers to the corresponding regions of the genome. PCR products were analyzed by electrophoresis in 4% polyacrylamide gel followed by staining with ethidium bromide.
Results. In the course of a molecular genetic study, a statistically significant predominance of the homozygous AA genotype and the A allele of the MMP-9 (rs11697325) gene polymorphism was observed in the group of patients with RA, both separately and in association with AH, in comparison with the data of control groups. The risk of developing RA estimated by the odds ratio (OR) in carriers of the AA genotype of the MMP-9 gene is 1.8 times higher (95% confidence interval CI 1.1362.950; p=0.02) than in carriers of the GG and GA genotypes; in carriers of the A allele, the risk of developing RA is 1.6 times higher compared to the G allele (95% CI 1.1192.578; p=0.01). The OR risk of developing RA in association with hypertension in carriers of the AA genotype of the MMP-9 gene is 2.8 times higher (95% CI 1.2836.54; p=0.04) compared to GA and GG genotypes, 2.1 times higher in carriers of the A allele (95% CI 1.1134.127; p=0.02) compared to the G allele.
Conclusion. Thus, the results of the study indicate that the homozygous AA genotype and the A allele of the MMP-9 (rs11697325) gene polymorphism are the predictors of the development of RA both as a separate nosological unit and in association with AH.
Medical and social characteristics of people with disability and neuromuscular, skeletal, and movement-related disorders
Authors: Povorinskii Anton A. , Vladimirova Oksana N. , Shoshmin Alexander V. , Riabokon Anna G.
Published: September 2022

BACKGROUND:Measures of growth are important for creating a construction and expansion system of opportunities for the constituents of the Russian Federation. The need for complex rehabilitation in people with impaired neuromuscular, skeletal, and movement-related functions is still not fully understood.
AIM:This pilot study aimed to determine the need for comprehensive rehabilitation of adults with neuromuscular, skeletal, and movement-related functions according to the main indicators of primary disability.
MATERIALS AND METHODS:The comparative analysis of the dynamics of newly detected (primary) disabilities in the Russian Federation due to all causes and disorders of neuromuscular, skeletal, and movement-related functions (categories b710b799 according to the International Classification of Functioning, Disabilities and Health) was conducted. Indicators in the Leningrad region were analyzed from 2016 to 2020.
RESULTS:The need for rehabilitation in the Leningrad region is lower than that in the whole country. Individuals with neuromuscular, skeletal, and movement-related disorders aged 1844 years need the most intensive rehabilitation.
CONCLUSIONS:The results of this study revealed that the decrease in overall primary disability is faster than the decrease in primary disability in the target group. The prevention and rehabilitation of neuromuscular and statodynamic disorders were slower, whereas the need for rehabilitation was higher in the specific-cause group than in the all-cause group.
Disability indicators for the social protection and rehabilitation measures in the population of the Russian Federation
Authors: Goryainova Marina V. , Karasaeva Lyudmila A. , Nurova Aminat A. , Pavlova Stefanida V , Azovtsev Denis Yu , Goryainov Igor V.
Published: September 2022

BACKGROUND:To improve social policy and to study the mechanisms of public administration, it is important to analyze the trends in the development of the social phenomenon population disability. The need for a systematic analysis in the planning and regulation of social protection measures for people with disability and rehabilitation to minimize the risks of negative socioeconomic consequences leads to a long-term comprehensive study and analysis of disability indicators in the population of the Russian Federation.
AIM:To identify the medical and social characteristics of the state and trends of disability in the Russian Federation and St. Petersburg for 20152019.
MATERIALS AND METHODS:The study analyzed people with primary disability living in St. Petersburg and the Russian Federation. Data were obtained from the State Statistical Reporting 7 Social Security. Analytical, expert assessment methods, and statistical analysis were performed.
RESULTS:During the study period (20142019), the level of primary disability in the adult population of the Russian Federation tended to decrease: in 2015, it was 58.9 per 10 thousand adult populations, and in 2019, it was 53.1 per 10 thousand people. The dynamics showed an uneven rate of decrease in the level of primary disability, with a peak decline in 2016. In the analysis of the indicators of people with primary disability by age, for over 5 years, the proportion of people of working age and with disabilities decreased from 46.8% in 2015 to 42.3% in 2019. A study of the need for vocational rehabilitation measures for people with disability, specifically the need to create special jobs for the employment of people with primary and secondary disabilities, showed that medical and social specialists identified the need to create special jobs for 27.7% of the analyzed population (n=15,977), and the largest share of recommendations on the need to create a special workplace was issued to people with secondary disability, i.e., 89.8% (n=14,341). The share of the recommendations on the creation of special jobs for people with secondary disability was 2.6 times higher than for those with primary disability, with an average of 72.3% (n=41,769), and recommendations were drawn up mainly for people with secondary disability, with 88.4% (n=36,937).
CONCLUSIONS:At present, it is relevant to plan the socioeconomic costs for the implementation of social and vocational rehabilitation programs of people with disability and the creation of conditions for their employment in special jobs. This enables the delivery of organized and optimal rehabilitation for the constituents of the Russian Federation.
A scoring system to reflect persistent blood and immune system dysfunctions in the International Classification of Functioning in people with disabilities and HIV infection
Authors: Ugleva Elena M. , Yamshchikova Tatyana Y. , Vladimirova Oksana N , Karasaeva Lyudmila A.
Published: September 2022

The article highlights the issues the International Classification of Functioning, which is being implemented worldwide to describe the functioning and limitations of human activity. The components are distinguished as follows: the functions and structures of the organism, activity, and participation―the performance of an action by an individual and his/her involvement in a life situation, as well as personal and environmental factors. In the Russian Federation, for the first time in a regulatory document (Order of the Ministry of Labor of Russia, dated August 27, 2019, N 585n), the International Classification of Functioning indicators were used to characterize persistent disorders of human functions.
HIV infection is characterized by damage to the immune system with a decrease in the bodys resistance, which results in various diseases, such as secondary (opportunistic) infections and oncological, hematological, autoimmune, and lymphoproliferative diseases. A feature of HIV infection is the multiple organicity of lesions and the variety of clinical symptoms, which explains the diversity of impaired body functions reflected in the Order of the Ministry of Labor of Russia, in particular cardiovascular, respiratory, digestive, immune, endocrine, urinary system, neuromuscular, skeletal and movement-related (statodynamic), mental functions, blood, and metabolism disorders.
The article highlights the issues of using the International Classification of Functioning in people with HIV infection or acquired immunodeficiency syndrome as a score to reflect the severity of persistent body disorders, particularly blood and immune system disorders, and the possibility for its use in people with disability.
The paper presents a clinical example of a patient aged 34 years suffering from HIV infection, severe cellular immunodeficiency, complicated by pneumocystis pneumonia, candidiasis stomatitis, cheilitis, cachexia against the background of chronic viral hepatitis B and C, and poly-drug addiction with a second degree of dependence. The International Classification of Functioning in people with HIV infection or acquired immunodeficiency syndrome as a point assessment reflects the severity of persistent body disorders particularly blood and the immune system disorders and the possibility for its use in people with disabilities.
VIBRATION FORECAST IN EUROPE FROM THE RESULTS OF GROUNDWATER MONITORING ON THE TERRITORY OF UKRAINE
Authors:   Sumy State University, Faculty of Electronics and Information Technologies, Department of Computer Science, Sumy, Ukraine, NAHORNYI VOLODYMYR , PIGULEVSKIY PETR ,   Institute of Geophysics S.I. Subbotin NASU, Seismic Hazard Department with seat in Kiev, Ukraine
Published: September 2022

The article provides theoretical and practical arguments regarding the possibility of predicting local and strong distant earthquakes around the world, based on the detection of anomalous behavior of the groundwater physical properties in the Earth's tectonically stressed zones before local and strong earthquakes. The authors suggest that many strong and major events can be predicted at least a few months before they occur. The theoretical positions of the authors are confirmed by the successful prediction of an earthquake that occurred in Ukraine on January 21, 2022.
FRAMEWORK FOR MILLING PROCESS MONITORING
Authors:   Czech Technical University in Prague, Czech Institute of Informatics, Robotics and Cybernetics, Department of Industrial Production and Automation, Prague, Czech Republic, SVEDA JIRI , KOLAR PETR ,   Czech Technical University in Prague, Czech Institute of Informatics, Robotics and Cybernetics, Department of Industrial Production and Automation, Prague, Czech Republic, RYTIR MICHAL ,   Czech Technical University in Prague, Czech Institute of Informatics, Robotics and Cybernetics, Department of Industrial Production and Automation, Prague, Czech Republic, FOJTU PETR ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment, Research Centre of Manufacturing Technology, Prague, Czech Republic, FIALA STEPAN ,   Czech Technical University in Prague, Czech Institute of Informatics, Robotics and Cybernetics, Department of Industrial Production and Automation, Prague, Czech Republic, CHLADEK STEPAN ,   Czech Technical University in Prague, Czech Institute of Informatics, Robotics and Cybernetics, Department of Industrial Production and Automation, Prague, Czech Republic, KOZLOK TOMAS ,   TOS VARNSDORF a.s., Varnsdorf, Czech Republic, MACHALKA MARTIN ,   TAJMAC-ZPS, a.s., Zlin, Czech Republic
Published: September 2022

Modern machining systems use horizontal and vertical data integration for the automatic monitoring and quality control of the machining operations. There are currently available some comprehensive papers focused on high-level system integration. Independently of that, there are also multiple publications focused on the automatic monitoring of specific machining operations. There is lack of presented connections between the high-level proposals and the operation-level methods. This paper proposes a framework for milling process monitoring that covers both mentioned levels, i.e., the system complexity as well as particular operation details. The data model consisting of five key objects (cutting tool management; machine tool; workpiece; machining operation and user) is presented within the framework.
Impacto de la orientación estratégica en el desempeño organizativo: efecto mediador del capital intelectual
Authors: Sepúlveda-Rivillas Claudia Inés , Restrepo-Ramírez Carlos Gilberto , Gómez Montoya Mariana
Published: September 2022

El objetivo del presente estudio es analizar empíricamente el impacto de la orientación estratégica (OE) sobre el desempeño organizativo (DO) considerando el efecto mediador del capital intelectual (CI). El análisis se realizó utilizando una metodología cuantitativa con alcance descriptivo y correlacional, considerando una muestra de 1.572 empresas manufactureras en Colombia a partir de la información suministrada en la Encuesta de Desarrollo e Innovación Tecnológica de la Industria Manufacturera (EDIT) para los años 2017-2018. Los resultados muestran que existe una relación positiva y significativa entre  la OE y el DO de manera directa y mediada por el CI. Esta investigación proporciona evidencia empírica sobre la forma como la OE impacta el DO, tanto directamente como a través del CI; además, se generan implicaciones prácticas para la toma de decisiones organizativas que conduzcan al logro de los objetivos propuestos y a la obtención de ventajas competitivas