bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Cycloadditions of Noncomplementary Substituted 1,2,3‐Triazines.
Authors: Anderson Erin D. , Duerfeldt Adam S. , Zhu Kaicheng , Glinkerman Christopher M. , Boger Dale L.
Published: March 2015

Cycloaddition reactions of substituted 1,2,3‐triazines with amidines, enamines and ynamines allow the synthesis of pyridine, pyrimidine and pyridazine derivatives.
ChemInform Abstract: A Simple, Mild and Environmentally Benign Procedure for the Cleavage of Carbon—Nitrogen Double Bonds Using NaBrO3 in the Presence of [bmim]HSO4.
Authors: Lumb Anshika , Rajeswari M. , Khurana Jitender M.
Published: March 2015

This method is applicable for a broad range of C—N double bond derivatives giving ketones or aldehydes in good yields
ChemInform Abstract: Versatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water.
Authors: Talwar Dinesh , Wu Xiaofeng , Saidi Ourida , Salguero Noemi Poyatos , Xiao Jianliang
Published: March 2015

Iridium catalysts (I) are found to be optimal for the reaction.
ChemInform Abstract: A New Method for Thiomethylation of Hydroxy‐1,4‐naphthoquinones with N‐Acetyl‐L‐cysteine; First Synthesis of Fibrostatins B, C, and D.
Authors: Sabutskii Yuri E. , Polonik Sergey G. , Denisenko Vladimir A. , Dmitrenok Pavel S.
Published: March 2015

This method was successfully used in the first synthesis of fibrostatins B, C, and D (not shown in scheme).
ChemInform Abstract: Ru/C: A Simple Heterogeneous Catalyst for the Amination of Azoles under Ligand Free Conditions.
Authors: Harsha Vardhan Reddy K. , Anil Kumar B. S. P. , Prakash Reddy V. , Uday Kumar R. , Nageswar Y. V. D.
Published: March 2015

The amination of 2‐haloazoles such as (I) and (VII) with a broad range of aminating reagents, is described affording the corresponding 2‐aminoazole derivatives in good yields.
ChemInform Abstract: trans‐Selective Radical Silylzincation of Ynamides.
Authors: Romain Elise , Fopp Carolin , Chemla Fabrice , Ferreira Franck , Jackowski Olivier , Oestreich Martin , Perez‐Luna Alejandro
Published: March 2015

The radical silylzincation of ynamides (I) and (IX) followed by quenching with NH4Cl and NH3 leads to desired β‐silylenamides (III) and (X), resp., with high trans‐selectivity.
ChemInform Abstract: Atom‐ and Step‐Economical Preparation of Reduced Knoevenagel Adducts Using CO as a Deoxygenative Agent.
Authors: Kolesnikov Pavel N. , Usanov Dmitry L. , Barablina Evgeniya A. , Maleev Victor I. , Chusov Denis
Published: March 2015

The rhodium catalyzed reactions of various aldehydes and cyclohexanone with active methylene compounds in the presence of carbon monoxide as deoxygenative agent provides reduced Knoevenagel adducts in moderate to good yields.
ChemInform Abstract: Rhodium‐Catalyzed Alkylation of C—H Bonds in Aromatic Amides with α,β‐Unsaturated Esters.
Authors: Shibata Kaname , Chatani Naoto
Published: March 2015

The regioselective alkylation of aromatic amides such as (I), (IV), (VII), and (IX) containing an 8‐aminoquinoline moiety as directing group with α,β‐unsaturated carbonyl compounds is described.
ChemInform Abstract: Room‐Temperature Chromium(II)‐Catalyzed Direct Arylation of Pyridines, Aryl Oxazolines, and Imines Using Arylmagnesium Reagents.
Authors: Kuzmina Olesya M. , Knochel Paul
Published: March 2015

The Tms‐group in (IV), (VI), and (X) prevents double arylation and can be further used to introduce a second aryl substituent.
ChemInform Abstract: Copper‐Catalyzed Regioselective Oxytrifluoromethylation of Allenes Using a CF3‐Transfer Reagent.
Authors: Wang Yanan , Jiang Min , Liu Jin‐Tao
Published: March 2015

The title reaction gives the trifluoromethyl substituted terminal alkenes.
ChemInform Abstract: Enantioselective Olefin Metathesis with Cyclometalated Ruthenium Complexes.
Authors: Hartung John , Dornan Peter K. , Grubbs Robert H.
Published: March 2015

Enantioenriched complexes incorporating cyclometalated NHC ligands catalyze (Z)‐ and enantioselective asymmetric ring opening/cross metathesis reactions of norbornenes and cyclobutenes, and the difference in ring strain between these two compounds leads to different propagating species in the catalytic cycle.
ChemInform Abstract: Asymmetric α‐Oxyamination of Aldehydes by Synergistic Catalysis of Imidazolethiones and Metal Salts.
Authors: Liang Xianrui , Li Na , Chen Xinlei , Su Weike
Published: March 2015

The asymmetric α‐oxyamination of alcohols (I) is described.
ChemInform Abstract: Domino‐Hydroformylation/Aldol Condensation Catalysis: Highly Selective Synthesis of α,β‐Unsaturated Aldehydes from Olefins.
Authors: Fang Xianjie , Jackstell Ralf , Franke Robert , Beller Matthias
Published: March 2015

Excellent chemoselectivity is observed in the intermolecular hydroformylation/cross‐aldol condensation reactions of aromatic and aliphatic aldehydes.
ChemInform Abstract: Cobalt‐Catalyzed Carboxylation of Propargyl Acetates with Carbon Dioxide.
Authors: Nogi Keisuke , Fujihara Tetsuaki , Terao Jun , Tsuji Yasushi
Published: March 2015

Alkynyl group‐containing α‐monosubstituted and α,α‐disubstituted carboxylic acids are obtained with moderate to good yields.
ChemInform Abstract: Synthesis of α‐Functionalized Amides by a Ritter Reaction in the Presence of NaHSO4/SiO2.
Authors: Hayakawa Mamiko , Aoyama Tadashi , Kobayashi Toshiya , Takido Toshio , Kodomari Mitsuo
Published: March 2015

The reaction of (Ia) with (VIII) is also performed in chlorobenzene requiring significantly shorter reaction times, but yielding slightly to significantly less product.
ChemInform Abstract: Sulfoximine Assisted Pd(II)‐Catalyzed Bromination and Chlorination of Primary β‐C(sp3)—H Bond.
Authors: Rit Raja K. , Yadav M. Ramu , Ghosh Koushik , Shankar Majji , Sahoo Akhila K.
Published: March 2015

Novel MPyS‐directing‐group‐assisted bromination and chlorination of primary β‐C(sp3)—H bonds of aliphatic acid derivatives is demonstrated for the first time.
ChemInform Abstract: Synthesis of α‐Peroxyesters via Organocatalyzed O—H Insertion of Hydroperoxides and Aryl Diazoesters.
Authors: Fisher Thomas J. , Mattson Anita E.
Published: March 2015

Hydrogen‐bond donors catalyze O‐H insertions of hydroperoxides and α‐aryl diazoesters to afford an unprecedented class of organic peroxides.
ChemInform Abstract: Enantioselective Construction of Functionalized Cyclopentanes by a Relay Ring‐Closing Metathesis and Chiral Amine (Thio)urea‐Promoted Michael Addition.
Authors: Zhang Yinan , Song Xixi , Chen Xiaobei , Song Aiguo , Zhang Shilei , Wang Wei
Published: March 2015

In some cases application of Grubbs first generation catalyst instead of Grubbs second generation catalyst upon the second addition of the catalyst increases the enantiomeric excess of the product.
ChemInform Abstract: Construction of Bicyclo[3.2.1]octanes with Four Stereogenic Centers by Organocatalytic Domino Michael/Aldol Reaction.
Authors: Lefranc A. , Gremaud L. , Alexakis A.
Published: March 2015

A general and direct diastereo‐ and enantioselective organocatalyzed domino Michael/aldol reaction to form polysubstituted chiral bicyclo[3.2.1]octanes is developed.
ChemInform Abstract: Catalytic Methylation of Aromatic Amines with Formic Acid as the Unique Carbon and Hydrogen Source.
Authors: Savourey Solene , Lefevre Guillaume , Berthet Jean‐Claude , Cantat Thibault
Published: March 2015

The formation of the N—Me group proceeds via a formylation/transfer hydrogenation pathway.
ChemInform Abstract: Sc(OTf)3‐Catalyzed Transfer Diazenylation of 1,3‐Dicarbonyls with Triazenes via N—N Bond Cleavage.
Authors: Liu Cong , Lv Jian , Luo Sanzhong , Cheng Jin‐Pei
Published: March 2015

This simple transfer diazenylation reaction exhibits good functional group compatibility, and provides a convenient approach for the synthesis of highly functionalized azo compounds.
ChemInform Abstract: Catalytic Enantioselective Addition of Aryl Grignard Reagents to Ketones.
Authors: Fernandez‐Mateos Emilio , Macia Beatriz , Yus Miguel
Published: March 2015

A range of starting ketones and aryl Grignards can be used under mild conditions in a one‐pot process to produce the desired tertiary alcohols with moderate to good yields and enantioselectivities.
ChemInform Abstract: Direct Carboxylation of Simple Arenes with CO2 Through a Rhodium‐Catalyzed C—H Bond Activation.
Authors: Suga Takuya , Mizuno Hajime , Takaya Jun , Iwasawa Nobuharu
Published: March 2015

A novel method for direct carboxylation of simple arenes with 1 atm CO2 through a rhodium‐catalyzed C—H bond activation without the assistance of a directing group is developed.
ChemInform Abstract: Chemo‐, Regio‐ and Stereoselective Heck Arylation of Allylated Malonates: Mechanistic Insights by ESI‐MS and Synthetic Application Toward 5‐Arylmethyl‐γ‐lactones.
Authors: Oliveira Caio C. , Marques Marcelo V. , Godoi Marla N. , Regiani Thais , Santos Vanessa G. , dos Santos Emerson A. F. , Eberlin Marcos N. , Sa Marcus M. , Correia Carlos R. D.
Published: March 2015

The Heck arylation of allylated malonate (I) employing aryldiazonium salts (II) as the aryl‐transfer agents is described.
ChemInform Abstract: Synthesis of α‐Methylidene‐γ‐amino Acid Esters from Aldehydes via an Aminative Umpolung Strategy.
Authors: Xu Juan , Chen Jing , Yang Qin , Ding Lei , Liu Xuliang , Xu Dongfang , Zhao Baoguo
Published: March 2015

In situ prepared α‐imino anions react with Morita—Baylis—Hillman adducts to form the title compounds (III) and (VI).
ChemInform Abstract: Specific 1,2‐Hydride Shift in the Boron Trifluoride Catalyzed Reactions of Aromatic Aldehydes with Diazoacetonitrile: Simple Synthesis of β‐Ketonitriles.
Authors: Yang Zhanhui , Son Kwon‐Il , Li Siqi , Zhou Bingnan , Xu Jiaxi
Published: March 2015

Mild conditions and a short reaction time result in a successful preparation of the title compounds, required as important synthetic intermediates.
ChemInform Abstract: Catalytic Enantioselective Alkylation of Sulfenate Anions to Chiral Heterocyclic Sulfoxides Using Halogenated Pentanidium Salts.
Authors: Zong Lili , Ban Xu , Kee Choon Wee , Tan Choon‐Hong
Published: March 2015

The use of halogenated pentadinium chlorides as chiral organocatalysts allows a highly enantioselective alkylation of sulfenate anions derived from (II) to yield enantioenriched sulfoxides.
ChemInform Abstract: Iron‐Catalyzed [2 + 2 + 2] Cycloaddition of Trifluoromethyl Group Substituted Unsymmetrical Internal Alkynes.
Authors: Minakawa Maki , Ishikawa Tomoki , Namioka Junya , Hirooka Souichirou , Zhou Biao , Kawatsura Motoi
Published: March 2015

The title reaction affords the corresponding trifluoromethyl group substituted benzene derivatives in high yield with excellent selectivity.
ChemInform Abstract: Iron‐Catalyzed Coupling of Aryl Sulfamates and Aryl/Vinyl Tosylates with Aryl Grignards.
Authors: Agrawal Toolika , Cook Silas P.
Published: March 2015

In contrast to previous reports with aryl chlorides, the title coupling reaction with aryl sulfamates proceeds with low levels of the Grignard homocoupling side reaction.
ChemInform Abstract: Palladium and Copper‐Catalyzed Ligand‐Free Coupling of Phenylhydrazines in Water.
Authors: Chauhan Parul , Ravi Makthala , Singh Shikha , Raju Kanumuri S. R. , Bajpai Vikas , Kumar Brijesh , Wahajuddin Wahajuddin , Yadav Prem P.
Published: March 2015

The novel ligand‐free palladium‐catalyzed homo‐ and cross‐coupling reactions of water‐soluble phenylhydrazines yield biaryls.
ChemInform Abstract: Nickel‐Catalyzed Desulfitative Suzuki—Miyaura Cross‐Coupling of N,N‐Disulfonylmethylamines and Arylboronic Acids.
Authors: Chen Liangshun , Lang Hongyue , Fang Lei , Yu Jianjun , Wang Limin
Published: March 2015

Extrusion of SO2 from the starting amines affords the aryl source for the coupling reaction.
ChemInform Abstract: A Metal‐Free One‐Pot Cascade Synthesis of Highly Functionalized Biaryl‐2‐carbaldehydes.
Authors: Challa Chandrasekhar , Vellekkatt Jamsheena , Ravindran Jaice , Lankalapalli Ravi S.
Published: March 2015

A variety of biaryl‐2‐carbaldehydes (III) is readily prepared by reaction of dienes (I) with cinnamaldehydes in the presence of allylamine and TFA.
ChemInform Abstract: Room‐Temperature and Transition‐Metal‐Free Mizoroki—Heck‐Type Reaction. Synthesis of E‐Stilbenes by Photoinduced C—H Functionalization.
Authors: Guastavino Javier F. , Buden Maria E. , Rossi Roberto A.
Published: March 2015

Detailed investigations concerning the reaction conditions are described: the preparation of the desired stilbenes works best without an extra solvent within a short time [i.e.
ChemInform Abstract: Catalytic Asymmetric Synthesis of Sterically Hindered Tertiary α‐Aryl Ketones.
Authors: Doran Robert , Guiry Patrick J.
Published: March 2015

The substrates are prepared following the procedure shown for (III).
ChemInform Abstract: AZT‐Prolinamide: The Nucleoside Derived Pyrrolidine Catalysts for Asymmetric Aldol Reactions Using Water as Solvent.
Authors: Naresh Tumma , Kumar Togapur Pavan , Haribabu Kothapalli , Chandrasekhar Srivari
Published: March 2015

New nucleoside‐based chiral prolinamides are synthesized and applied in enantioselective aldol reaction of aldehydes with ketones to give β‐hydroxyl carbonyl compounds in high yields with good stereoselectivity.
ChemInform Abstract: Cyclization of η3‐Benzylpalladium Intermediates Derived from Carbene Insertion.
Authors: Gutman Eugene S. , Arredondo Vanessa , Van Vranken David L.
Published: March 2015

1‐Arylindanes and 1‐aryltetralines (XI) are prepared by palladium catalyzed carbenylative cyclization reaction of aryl iodide derivatives and N‐tosylhydrazines.
ChemInform Abstract: Dual Gold Catalysis: Synthesis of Polycyclic Compounds via C—H Insertion of Gold Vinylidenes.
Authors: Wieteck Marcel , Tokimizu Yusuke , Rudolph Matthias , Rominger Frank , Ohno Hiroaki , Fujii Nobutaka , Hashmi A. Stephen K.
Published: March 2015

This method provides access to complex polycyclic compounds with quaternary carbon centers from non‐conjugated diynes.
ChemInform Abstract: Chiral Spirooxindole—Butenolide Synthesis Through Asymmetric N‐Heterocyclic Carbene‐Catalyzed Formal (3 + 2) Annulation of 3‐Bromoenals and Isatins.
Authors: Zheng Chenguang , Yao Weijun , Zhang Yucheng , Ma Cheng
Published: March 2015

The spirooxindole (VIIe) is converted to a more complex spirocyclic compound by annulation with benzyne precursors.
ChemInform Abstract: Manganese Ferrite Nanoparticle Catalyzed Tandem and Green Synthesis of Spirooxindoles.
Authors: Ghahremanzadeh Ramin , Rashid Zahra , Zarnani Amir‐Hassan , Naeimi Hossein
Published: March 2015

A novel one‐pot three‐component reaction of isatins, anilinolactones, and malonitrile furnishes spirooxindoles with potential biological activity.
ChemInform Abstract: tert‐Butyl Hydroperoxide and Tetrabutylammonium Iodide‐ Promoted Free Radical Cyclization of α‐Azido‐N‐arylamides.
Authors: Li Dianjun , Yang Tonghao , Su Hailin , Yu Wei
Published: March 2015

It is demonstrated, that the reagent combination of tBuOOH and Bu4NI affects the oxidative cyclizations of α‐ethoxycarbonyl α‐azido‐N‐arylamides.
ChemInform Abstract: ipso‐Iodocyclization of para‐Substituted 4‐Aryl‐1‐alkenes Leading to 3‐Iodo‐1‐azaspiro[4.5]deca‐6,9‐diene‐2,8‐diones.
Authors: Wu Cui‐Yan , Deng Guo‐Bo , Hu Ming , Wei Wen‐Ting , Li Jin‐Heng
Published: March 2015

The corresponding reaction of an N‐acetyl instead of N‐methyl substituted 4‐aryl‐1‐alkene derivatives yields only trace amounts of product.
ChemInform Abstract: Formation of Persulfate from Sodium Sulfite and Molecular Oxygen Catalyzed by H5PV2Mo10O40 — Aerobic Epoxidation and Hydrolysis.
Authors: Rubinstein Amir , Carmeli Raanan , Neumann Ronny
Published: March 2015

The H5PV2Mo10O40 polyoxometalate catalyzes the electron transfer oxidation of sulphite to yield a sulphite radical.
ChemInform Abstract: Introducing Deep Eutectic Solvents as Biorenewable Media for Au(I)‐Catalyzed Cycloisomerization of γ‐Alkynoic Acids: An Unprecedented Catalytic System.
Authors: Rodriguez‐Alvarez Maria J. , Vidal Cristian , Diez Josefina , Garcia‐Alvarez Joaquin
Published: March 2015

The cycloisomerization of γ‐alkynoic acids into cyclic enol‐lactones proceeds under mild and aerobic conditions and, for the first time, in a deep eutectic solvent (choline chloride/urea).
ChemInform Abstract: Synthesis of 2‐Vinylbenzofurans via the Copper‐Catalyzed Multicomponent Reactions Involving an Oxa‐Michael/Arylation/Vinylation Cascade.
Authors: Wan Jie‐Ping , Wang Hang , Liu Yunyun , Ding Hanfeng
Published: March 2015

Title compounds (V) are prepared via the multicomponent reaction of o‐iodophenols (I), in situ generated allenes, and dichloromethane (IV).
ChemInform Abstract: Metal‐Free n‐Et4NBr‐Catalyzed Radical Cyclization of Disulfides and Alkynes Leading to Benzothiophenes under Mild Conditions.
Authors: Yang Daoshan , Yan Kelu , Wei Wei , Tian Laijin , Li Qinghe , You Jinmao , Wang Hua
Published: March 2015

The green and efficient method succeeds with almost identical yields using diethyl instead of dimethyl acetylenedicarboxylate as the C1‐source, but fails with terminal alkynes and 1,2‐dialkyl or 1,2‐diarylalkynes.
ChemInform Abstract: Efficient and Green Synthesis of N‐Aryl Pyrroles Catalyzed by Ionic Liquid [H‐NMP][HSO4] in Water at Room Temperature.
Authors: Naeimi Hossein , Dadaei Mahla
Published: March 2015

The catalyst is recyclable and reusable at least 4 times.
ChemInform Abstract: Tandem One‐Pot Synthesis of Polysubstituted NH‐Pyrroles Involving the Palladium‐Catalyzed Intramolecular Oxidative Amination of the Zinc Bromide Complex of β‐Enamino Esters.
Authors: Kim Ju Hyun , Choi Suh Young , Bouffard Jean , Lee Sang‐gi
Published: March 2015

The sequence proceeds via Zn complexes of type (IV) and affords the target compounds in a regioselective manner.
ChemInform Abstract: Synthesis of N‐(2,3,4,5,6‐Pentafluorobenzyloxy)‐γ‐lactams by Rhodium‐Catalyzed Cyclization of Diazo Amides.
Authors: Budny Marcin , Nowak Magdalena , Wojtczak Andrzej , Wolan Andrzej
Published: March 2015

A series of diazo amides bearing the ‐Fbo protecting group is successfully cyclized to γ‐lactam structures with different yields and stereoselectivities.
ChemInform Abstract: 1,4‐Diazabicyclo[2.2.2]octane‐Mediated Ring Opening of 1‐Acetylcyclopropanecarboxamides and Its Application to the Construction of 3‐Alkylated γ‐Lactams.
Authors: Li Ling , Wei Enxiang , Lin Shaoxia , Liu Bing , Liang Fushun
Published: March 2015

The reaction proceeds with the formation of the DABCO‐containing zwitter ions [cf.
ChemInform Abstract: Phosphine‐Catalyzed [4 + 1] Annulation of 1,3‐(Aza)dienes with Maleimides: Highly Efficient Construction of Azaspiro[4.4]nonenes.
Authors: Yang Mei , Wang Tianyi , Cao Shixuan , He Zhengjie
Published: March 2015

Compounds (VII) are isolated as diastereomeric mixtures due to hindered rotation of the aryl groups caused by steric hindrance of the ortho‐substituents.
ChemInform Abstract: Multicomponent Decarboxylative Allylations.
Authors: Ariyarathna Yamuna , Tunge Jon A.
Published: March 2015

The reaction of Meldrum′s acid derivatives (II), pyrrolide (I) and allyl carbonates (III) allows a multicomponent decarboxylative coupling to form allylated acyl pyrroles (IV).
ChemInform Abstract: Preparation of 3‐Diazoindolin‐2‐imines via Cascade Reaction Between Indoles and Sulfonylazides and Their Extensions to 2,3‐Diaminoindoles and Imidazo[4,5‐b]indoles.
Authors: Sheng Guorong , Huang Kai , Chi Zhihao , Ding Hualong , Xing Yanpeng , Lu Ping , Wang Yanguang
Published: March 2015

3‐Diazoindolin‐2‐imines (III) and (X) are prepared from indoles (I) and sulfonylazides via an electronically matched 1,3‐dipolar cycloaddition/dehydroaromatization/ring‐opening cascade.
ChemInform Abstract: Palladium‐Catalyzed Difunctionalization of Alkynes via C—N and S—N Cleavages: A Versatile Approach to Highly Functional Indoles.
Authors: Zhao Fei , Zhang Dengyou , Nian Yong , Zhang Lei , Yang Wei , Liu Hong
Published: March 2015

This Pd‐catalyzed intramolecular aminoacylation of N‐substituted tertiary 2‐alkynylanilines proceeds via migration of the N‐substituent to C‐3 of the formed indole derivative while the reaction of secondary anilines (XIII) gives the corresponding N‐substituted indoles (XIV) only.
ChemInform Abstract: One‐Pot Approach to 1,2‐Disubstituted Indoles via Cu(II)‐Catalyzed Coupling/Cyclization under Aerobic Conditions and Its Application for the Synthesis of Polycyclic Indoles.
Authors: Gao Jilong , Shao Yingying , Zhu Jiaoyan , Zhu Jiaqi , Mao Hui , Wang Xiaoxia , Lv Xin
Published: March 2015

The title process is applied to the preparation of a variety of target compounds.
ChemInform Abstract: Metal‐Free Syntheses of Oxindole Derivatives via a Benzoylation/Substitution/Desulfonylation/Cyclization Cascade.
Authors: Niu Ben , Xie Ping , Zhao Wannian , Zhou Yang , Bian Zhaogang , Pittman Charles U. Jr. , Zhou Aihua
Published: March 2015

The novel metal‐free cascade reaction starts from aldehydes and methacrylamides and it enriches current methods of generating oxindole derivatives.
ChemInform Abstract: Rhodium(III)‐Catalyzed Intramolecular Redox‐Neutral Annulation of Tethered Alkynes: Formal Total Synthesis of (.+‐.)‐Goniomitine.
Authors: Zhou Bing , Du Juanjuan , Yang Yaxi , Li Yuanchao
Published: March 2015

The cyclization procedure affords indole structures bearing a C‐2 alkyl side chain with terminal amide function.
ChemInform Abstract: A Base‐Mediated Mild Sulfenylation of Indoles and Pyrrole with α‐Acylthiones.
Authors: Viglianisi Caterina , Marcantoni Enrico , Carapacchi Vanessa , Menichetti Stefano , Marsili Laura
Published: March 2015

Indole derivatives react with 1 equiv.
ChemInform Abstract: Shortcut Approach to Cyclopenta[b]indoles by [3 + 2] Cyclodimerization of Indole‐Derived Cyclopropanes.
Authors: Ivanova Olga A. , Budynina Ekaterina M. , Skvortsov Dmitriy A. , Trushkov Igor V. , Melnikov Mikhail Ya.
Published: March 2015

The products show moderate cytotoxicity in vitro.
ChemInform Abstract: An Intermolecular C—H Functionalization Method for the Synthesis of 3‐Hydroxy‐2‐oxindoles.
Authors: Chen Jinsen , Song Chao , Chen Pei , Zhu Jin
Published: March 2015

The reductive denitrosation‐triggered cyclization of substrates (I) leads readily to desired 3‐hydroxy‐2‐oxindoles.
ChemInform Abstract: An Efficient Route to Synthesize Isatins by Metal‐Free, Iodine‐Catalyzed Sequential C(sp3)—H Oxidation and Intramolecular C—N Bond Formation of 2′‐Aminoacetophenones.
Authors: Rajeshkumar Venkatachalam , Chandrasekar Selvaraj , Sekar Govindasamy
Published: March 2015

A series of isatins (II) is prepared by iodine‐catalyzed oxidation—cyclization of o‐aminoacetophenones (I) with DMSO as both a reagent and a solvent.
ChemInform Abstract: Palladium(0)‐Catalyzed Heck Reaction/C—H Activation/Amination Sequence with Diaziridinone: A Facile Approach to Indolines.
Authors: Zheng Huaiji , Zhu Yingguang , Shi Yian
Published: March 2015

A novel cascade reaction involving a Heck reaction/C—H activation/amination sequence with iodobenzenes (I), olefins such as (II), and di‐tert‐butyldiaziridine (III) providing access to a variety of polycyclic indolines, e.g. (IV), is reported.
ChemInform Abstract: A Cation‐Directed Two‐Component Cascade Approach to Enantioenriched Pyrroloindolines.
Authors: Wolstenhulme Jamie R. , Cavell Alex , Gredicak Matija , Driver Russell W. , Smith Martin D.
Published: March 2015

Using TBAB as the cationic catalyst and aryl isocyanides (II) gives pyrroloindolines (III) with good diastereoselectivity while alkyl isocyanides (V) give 1:1 mixtures of diastereomers (VI).
ChemInform Abstract: Copper‐Catalyzed One‐Pot Synthesis of N‐Aryl Oxazolidinones from Amino Alcohol Carbamates.
Authors: Mahy William , Plucinski Pawel K. , Frost Christopher G.
Published: March 2015

The synthetic utility of this cyclization is demonstrated in the synthesis of the reversible MAO‐A inhibitor Toloxatone (XII).
ChemInform Abstract: Electrochemical Intramolecular Aminooxygenation of Unactivated Alkenes.
Authors: Xu Fan , Zhu Lin , Zhu Shaobin , Yan Xiaomei , Xu Hai‐Chao
Published: March 2015

Addition of a nitrogen‐centered radical to alkenes generates a cyclized radical intermediate which is trapped by TEMPO (II).
ChemInform Abstract: Synthesis of 5‐(Fluoromethyl)‐4,5‐dihydroisoxazoles by Silver‐ Catalyzed Oxyfluorination of Unactivated Alkenes.
Authors: Liu Yan‐Yun , Yang Ji , Song Ren‐Jie , Li Jin‐Heng
Published: March 2015

The title synthesis features a new 1,2‐difunctionalization of unactivated alkenes using commercially available Selectfluor via a radical pathway.
ChemInform Abstract: Carbon Dioxide as a Primary Oxidant and a C1 Building Block.
Authors: Bors Istvan , Kaizer Jozsef , Speier Gabor , Giorgi Michel
Published: March 2015

3H‐Phenanthro[9,10‐d]oxazol‐2‐ones (III) are prepared either from 9,10‐phenanthrenequinone monoimines (I) in the presence of PPh3 or 2,3‐dihydro‐2,2,2‐triphenylphenanthro [9,10‐d]‐1,3,2‐λ5‐oxazaphospholes (IV) using CO2 as C1 building block.
ChemInform Abstract: Oxime‐Mediated Facile Access to 5‐Methylisoxazoles and Applications in the Synthesis of Valdecoxib and Oxacillin.
Authors: Dong Kui‐Yong , Qin Hai‐Tao , Bao Xing‐Xing , Liu Feng , Zhu Chen
Published: March 2015

The title reaction affords a variety of 5‐methylisoxazoles in moderate to good yields.
ChemInform Abstract: Heterogeneous Copper‐Catalyzed Cascade Three‐Component Reaction of Amines, Carbon Disulfide and 2‐Iodoanilines Leading to 2‐Aminobenzothiazoles.
Authors: Zhao Hong , He Wen , Yao Ruiya , Cai Mingzhong
Published: March 2015

2‐Aminobenzothiazoles are prepared from secondary amines, carbon disulfide, and iodoanilines in the presence of a immobilized copper catalyst in excellent yields.
ChemInform Abstract: Catalyst‐Free Tandem Ring‐Opening/Click Reaction of Acetylene‐Bearing Donor—Acceptor Cyclopropanes.
Authors: Flisar Michelle E. , Emmett Michael R. , Kerr Michael A.
Published: March 2015

The synthesis of (I) is described.
ChemInform Abstract: Rhodium‐Catalyzed Enantioselective [2 + 2 + 2] Cycloaddition of Tosylamide‐Linked 5‐Allenal and 5‐Allenone with Internal Alkynes.
Authors: Sakashita Kazuki , Masutomi Koji , Noguchi Keiichi , Tanaka Ken
Published: March 2015

This [Rh(cod)2]BF4/(S)‐BINAP‐catalyzed cycloaddition usually proceeds with high regioselectivity.
ChemInform Abstract: Synthesis of New and Known Dicoumarols in Aqueous Media: A Green and Convenient Procedure Promoted by Titanium(IV) Oxide Nanoparticles.
Authors: Khodabakhshi Saeed , Shahamirian Mozhgan , Baghernejad Mojtaba
Published: March 2015

A simple, green, and completely chemoselective synthesis of title compounds (III) from 4‐hydroxycoumarin (I) and various arylglyoxals (II) is accomplished.
ChemInform Abstract: Versatile Palladium‐Catalyzed C—H Olefination of (Hetero)arenes at Room Temperature.
Authors: She Zhijie , Shi Yang , Huang Yumin , Cheng Yangyang , Song Feijie , You Jingsong
Published: March 2015

The oxidative C—H cross coupling of arenes or hetarenes with linear or cyclic alkenes proceeds with the use of the in situ generated, highly electrophilic Pd‐species, e.g. [Pd(TFA)2].
ChemInform Abstract: Tandem Synthesis of Polysubstituted Pyridines via the Indium(III)‐Triflate‐Catalyzed Cycloaddition/Oxidative Aromatization of Blaise Reaction Intermediates with α,β‐Unsaturated Ketones.
Authors: Xuan Zi , Rathwell Kris , Lee Sang‐gi
Published: March 2015

In absence of oxygen in the second step, a subsequent oxidation stage is needed to achieve full aromatization of the pyridine ring.
ChemInform Abstract: Development of a Mild and Versatile Directed Cycloaddition Approach to Pyridines.
Authors: Bachollet Sylvestre P. J. T. , Vivat Jerome F. , Cocker Dean C. , Adams Harry , Harrity Joseph P. A.
Published: March 2015

A Lewis base directed cycloaddition of triazines with alkynylboranes allows the regioselective approach to highly substituted pyridine structures including bipyridines.
ChemInform Abstract: Selective C—N Bond‐Forming Reaction of 2,6‐Dibromopyridine with Amines.
Authors: Wang Lei , Liu Ning , Dai Bin , Hu Hengcai
Published: March 2015

The optimized conditions A) allow a relatively selective monoamination of the title compound (Ia).
ChemInform Abstract: Synthesis of Fluorescent 2,3,5,6‐Tetraalkynylpyridines by Site‐Selective Sonogashira‐Reactions of 2,3,5,6‐Tetrachloropyridines.
Authors: Ehlers Peter , Petrosyan Andranik , Neubauer Antje , Broese Timo , Lochbrunner Stefan , Ghochikyan Tariel V. , Saghyan Ashot S. , Langer Peter
Published: March 2015

Two series of 2,3,5,6‐tetraalkynylpyridines (V) and (VI) are prepared and their fluorescence is studied.
ChemInform Abstract: A Convenient Allenoate‐Based Synthesis of 2‐Quinolin‐2‐yl Malonates and β‐Ketoesters.
Authors: Selig Philipp , Raven William
Published: March 2015

N‐Protected o‐aminobenzaldehydes (I) react with α,γ‐dialkylallenoates (II) to yield 2,3‐disubstituted quinolines (III).
ChemInform Abstract: Enantioselective Deprotonative Ring Contraction of N1‐Methyl‐N4‐Boc‐benzo[e][1,4]diazepine‐2,5‐diones.
Authors: Antolak Stephanie A. , Yao Zhong‐Ke , Richoux Gary M. , Slebodnick Carla , Carlier Paul R.
Published: March 2015

Upon deprotonation, title compounds (I) undergo ring contraction to the corresponding quinolone‐2,4‐diones (II) with high enantioselectivity.
ChemInform Abstract: Cerium(IV)‐Catalyzed sp3 C—H Bond Oxidation of Glycine Derivatives: Radical Cation Prompted Dioxygen Activation in the Presence of Triarylamine.
Authors: Liu Jing , Wang Yaxin , Yu Liangliang , Huo Congde , Wang Xicun , Jia Xiaodong
Published: March 2015

Aerobic oxidation of glycine derivatives in the presence of an in situ generated triarylamine radical cation followed by reaction with styrene derivatives affords a wide variety of functionalized quinolines.
ChemInform Abstract: Synthesis of Isoquinolin‐4‐ols by Palladium‐Catalyzed Intramolecular Nucleophilic Addition of Aryl Iodides to Aldehydes.
Authors: Sole Daniel , Mariani Francesco , Fernandez Israel
Published: March 2015

The use of Et3N as the base is found to be essential for the Pd‐catalyzed cyclization reaction to give isoquinolin‐4‐ols.
ChemInform Abstract: Highly Stereoselective Synthesis of Functionalized Pyrrolo[3,2‐c]quinolines via N‐Heterocyclic Carbene Catalyzed Cascade Sequence.
Authors: Yang Yu‐Jie , Zhang Hai‐Rui , Zhu Shi‐Ya , Zhu Ping , Hui Xin‐Ping
Published: March 2015

Mannich—Michael‐lactamization cascade reaction of aromatic aldimines and 2‐bromoenals results in the formation of pyrroloquinolines with excellent diastereo‐ and enantioselectivities.
ChemInform Abstract: Recyclable Gold(III) Dipyridine Complex Immobilized on Fe3O4 Magnetic Nanoparticles: Synthesis of 2,6‐Dihydro[2,1‐a]isoindole under Mild Conditions.
Authors: Sadeghzadeh Seyed Mohsen
Published: March 2015

A novel heterogenized gold(III) catalyst is synthesized and used for the synthesis of dihydroisoindoles in water.
ChemInform Abstract: Greener and Expeditious One‐Pot Synthesis of Dihydropyrimidinone Derivatives Using Non‐commercial β‐Ketoesters via the Biginelli Reaction.
Authors: Rao G. B. Dharma , Anjaneyulu B. , Kaushik M. P.
Published: March 2015

This new one‐pot protocol furnishes the title compounds under solvent‐ and catalyst‐free conditions with better yields and in shorter reaction times than a previously reported two‐step reaction.
ChemInform Abstract: Asymmetric Hydrogenation of 2‐Aryl‐5,6‐dihydropyrazine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts.
Authors: Li Yong , He Yanmei , Chen Fei , Fan Qinghua
Published: March 2015

The first asymmetric hydrogenation of 2‐substituted and 2,3‐substituted 5,6‐dihydropyrazines catalyzed by a chiral cationic Ru‐diamine complex affords chiral piperazine derivatives with good enantioselectivity and good yield.
ChemInform Abstract: Enantioselective Synthesis of 3‐Substituted 1,2‐Oxazinanes via Organocatalytic Intramolecular Aza‐Michael Addition.
Authors: Cheng Shuanghua , Yu Shouyun
Published: March 2015

A variety of 3‐substituted 1,2‐oxazinanes (II) is obtained by quinine‐catalyzed intramolecular aza‐Michael reaction of enones (I) with moderate to high enantioselectivity.
ChemInform Abstract: Synthesis of 2‐(4H‐1,2,6‐Thiadiazin‐4‐ylidene)malononitriles.
Authors: Kalogirou Andreas S. , Koutentis Panayiotis A.
Published: March 2015

Reactions of 3,5‐disubstituted 4H‐1,2,6‐thiadiazin‐4‐ones with malonodinitrile as well as other CH2‐activated reactants show surprising effects on product formation, yield and limitations.
ChemInform Abstract: Ruthenium Catalyzed Cycloisomerization of Silicon‐Tethered 1,7‐Enynes to Give Exocyclic 1,3‐Dienes.
Authors: Kaminsky Lauren , Clark Daniel A.
Published: March 2015

This method is also applicable for non‐silicon‐tethered substrates as demonstrated in the synthesis of (XII).
ChemInform Abstract: Iridium(III)‐Catalyzed C—H Amidation of Arylphosphoryls Leading to a P‐Stereogenic Center.
Authors: Gwon Donghyeon , Lee Donggun , Kim Jiyu , Park Sehoon , Chang Sukbok
Published: March 2015

An iridium(III)‐catalyst system allows the direct amidation of arylphosphoryls with various sulfonyl azides under mild conditions and for the first time in an asymmetric manner.
ChemInform Abstract: Iridium‐Catalyzed Phosphoramidation of Arene C—H Bonds with Phosphoryl Azide.
Authors: Pan Changduo , Jin Ning , Zhang Honglin , Han Jie , Zhu Chengjian
Published: March 2015

33 examples
ChemInform Abstract: Silver‐Catalyzed Carbon—Phosphorus Functionalization of N‐(p‐Methoxyaryl)propiolamides Coupled with Dearomatization: Access to Phosphorylated Aza‐Decenones.
Authors: Wang Li‐Jing , Wang An‐Qi , Xia Yu , Wu Xin‐Xing , Liu Xue‐Yuan , Liang Yong‐Min
Published: March 2015

The title transformation involves phosphonation of propiolamides, 5‐exo cyclization, and dearomatization.
ChemInform Abstract: Preparation of Cyclohexenones from Acyclic (Pentadienyl)iron(1+) Cations: Synthetic Studies Directed Toward the A‐Ring of Dihydrotachysterols.
Authors: Manful Charles F. , Donaldson William A.
Published: March 2015

The synthesis of 3‐methyl‐4‐substituted cyclohexenones by reaction of stabilized carbon nucleophiles derived from activated methylene compounds with 3‐methylpentadienyl cation is described.
ChemInform Abstract: Development of a Concise Synthetic Approach to Access Oroxin A.
Authors: Chen Haijun , He Guihua , Li Cailong , Dong Longrong , Xie Xiaobo , Wu Jianlei , Gao Yu , Zhou Jia
Published: March 2015

An efficient synthetic approach to access oroxin A from inexpensive baicalin (I) is developed.
ChemInform Abstract: Total Synthesis of Aspeverin via an Iodine(III)‐Mediated Oxidative Cyclization.
Authors: Levinson Adam M.
Published: March 2015

The first total synthesis of the prenylated indole alkaloid aspeverin (I) is described.
ChemInform Abstract: Total Synthesis of Russuphelol: A Case of Mistaken Chirality.
Authors: Salih M. Quamar , Beaudry Christopher M.
Published: March 2015

The first total synthesis of russuphelol (I) is reported.
ChemInform Abstract: Coupling of Sterically Hindered Trisubstituted Olefins and Benzocyclobutenones by C—C Activation: Total Synthesis and Structural Revision of Cycloinumakiol.
Authors: Xu Tao , Dong Guangbin
Published: March 2015

The first total synthesis of the proposed structure of cycloinumakiol (I) and its C5 epimer (II) is presented.
ChemInform Abstract: A Highly Stable Zeotype Mesoporous Zirconium Metal—Organic Framework with Ultralarge Pores.
Authors: Feng Dawei , Wang Kecheng , Su Jie , Liu Tian‐Fu , Park Jihye , Wei Zhangwen , Bosch Mathieu , Yakovenko Andrey , Zou Xiaodong , Zhou Hong‐Cai
Published: March 2015

A zeotype mesoporous zirconium metal‐organic framework, [Zr6(O)4(OH)10(H2O)6 (TATB)2] (TATB: 4,4′,4′′‐s‐triazine‐2,4,6‐triyl‐tribenzoate) is solvothermally prepared from a mixture of ZrOCl2, TATB, and TFA in N,N‐diethylformamide (autoclave, 120 °C, 12 h).
ChemInform Abstract: The Formal Oxidation States of Iridium Now Run from ‐III to +IX
Authors: Pyykkoe Pekka , Xu Wen‐Hua
Published: March 2015

Review: 15 refs.
ChemInform Abstract: Multifunctional Tin Dioxide Materials: Advances in Preparation Strategies, Microstructure, and Performance
Authors: Chen Zhiwen , Wu Minghong , Shek Chan‐Hung , Wu C. M. Lawrence , Lai Joseph K. L.
Published: March 2015

Review: 56 refs.
ChemInform Abstract: Ultrathin Two‐Dimensional Inorganic Materials: New Opportunities for Solid State Nanochemistry
Authors: Sun Yongfu , Gao Shan , Lei Fengcai , Xiao Chong , Xie Yi
Published: March 2015

Review: 44 refs.
ChemInform Abstract: Ruthenium Tetroxide and Perruthenate Chemistry. Recent Advances and Related Transformations Mediated by Other Transition Metal Oxo‐Species
Authors: Piccialli Vincenzo
Published: March 2015

Review: literature of 2006‐2013; 208 refs.
ChemInform Abstract: Parity‐Controlled Self‐Assembly of Supramolecular Helices in a Gold(I)—Copper(II) Coordination System with Penicillamine and Bis(diphenylphosphino)alkane
Authors: Yoshinari Nobuto , Kakuya Atsushi , Lee Raeeun , Konno Takumi
Published: March 2015

Review: [25 refs.
ChemInform Abstract: Metal—Organic Molecular Cages: Applications of Biochemical Implications
Authors: Ahmad Nazir , Younus Hussein A. , Chughtai Adeel H. , Verpoort Francis
Published: March 2015

Review: 55 refs.
ChemInform Abstract: Organoiron‐Mediated Synthesis and Redox Activity of Organoiron‐Containing Dendrimers
Authors: Astruc Didier , Wang Yanlan , Rapakousiou Amalia , Diallo Abdou , Djeda Rodrigue , Ruiz Jaime , Ornelas Catia
Published: March 2015

Review: 88 refs.
ChemInform Abstract: Hydrogen Generation: Aromatic Dithiolate‐Bridged Metal Carbonyl Complexes as Hydrogenase Catalytic Site Models
Authors: Pandey Indresh Kumar , Natarajan Mookan , Kaur‐Ghumaan Sandeep
Published: March 2015

Review: 232 refs.
ChemInform Abstract: Recent Advances in Stereoselective [2 + 2 + 2] Cycloadditions
Authors: Amatore Muriel , Aubert Corinne
Published: March 2015

Review: [110 refs.
ChemInform Abstract: Novel DNA Catalysts Based on G‐Quadruplex for Organic Synthesis
Authors: Wang Li‐Xia , Xiang Jun‐Feng , Tang Ya‐Lin
Published: March 2015

Review: [26 refs.
ChemInform Abstract: Chitosan as a Sustainable Organocatalyst: A Concise Overview
Authors: El Kadib Abdelkrim
Published: March 2015

Review: 165 refs.
ChemInform Abstract: Diazo Compounds in Continuous‐Flow Technology
Authors: Mueller Simon T. R. , Wirth Thomas
Published: March 2015

Review: [44 refs.
ChemInform Abstract: Artificial Concurrent Catalytic Processes Involving Enzymes
Authors: Koehler Valentin , Turner Nicholas J.
Published: March 2015

Review: 157 refs.
ChemInform Abstract: Ionic Liquids in Catalysis
Authors: Steinrueck Hans‐Peter , Wasserscheid Peter
Published: March 2015

Review: 217 refs.
ChemInform Abstract: Polymer‐Encapsulated Metallic Nanoparticles as a Bridge Between Homogeneous and Heterogeneous Catalysis
Authors: Gross Elad , Dean Toste F. , Somorjai Gabor A.
Published: March 2015

Review: 65 refs.
ChemInform Abstract: Hierarchically Nanoporous Zeolites and Their Heterogeneous Catalysis: Current Status and Future Perspectives
Authors: Na Kyungsu , Somorjai Gabor A.
Published: March 2015

Review: 147 refs.
ChemInform Abstract: Surface Chemistry for Enantioselective Catalysis
Authors: Gellman Andrew J. , Tysoe Wilfred T. , Zaera Francisco
Published: March 2015

Review: 128 refs.
ChemInform Abstract: Supported Single‐Site Organometallic Catalysts for the Synthesis of High‐Performance Polyolefins
Authors: Stalzer Madelyn M. , Delferro Massimiliano , Marks Tobin J.
Published: March 2015

Review: 127 refs.
ChemInform Abstract: Early Steps of Homogeneous Catalysis in Rennes: Carbon Dioxide Incorporation, Alkyne Activation and Ruthenium Catalysis
Authors: Dixneuf Pierre H.
Published: March 2015

Review: 109 refs.
ChemInform Abstract: Transition Metal Catalyzed Borylation of Functional π‐systems
Authors: Shinokubo Hiroshi
Published: March 2015

Review: recent progress on borylation of large π‐conjugated systems such as porphyrins, perylene bisimides, hexabenzocoronenes and dipyrrins; 98 refs.
ChemInform Abstract: Methods of Synthesis of 1,3,4‐Oxadiazole‐2‐thiones : A Review
Authors: Khatale Pravin N. , Sivakumar T.
Published: March 2015

Review: 15 refs.
ChemInform Abstract: 2,5‐Diketopiperazines as Privileged Scaffolds in Medicinal Chemistry, Peptidomimetic Chemistry and Organocatalysis
Authors: Piarulli Umberto , Panzeri Silvia
Published: March 2015

Review: 124 refs.
ChemInform Abstract: Synthesis of Chromones and Their Applications During the Last Ten Years
Authors: Tawfik Hanaa A. , Ewies Ewies F. , El‐Hamouly Wageeh S.
Published: March 2015

Review: 150 refs.
ChemInform Abstract: Heterocycle Construction via Transition Metal‐Catalyzed C‐H Functionalization and C‐Heteroatom Bond Formation
Authors: Liu Yajun , Kim Jihye , Chae Junghyun
Published: March 2015

Review: 92 refs.
ChemInform Abstract: Role of Homogeneous Catalysis in Oligomerization of Olefins : Focus on Selected Examples Based on Group 4 to Group 10 Transition Metal Complexes
Authors: Breuil Pierre‐Alain R. , Magna Lionel , Olivier‐Bourbigou Helene
Published: March 2015

Review: 139 refs.
ChemInform Abstract: Cross‐Dehydrogenative‐Coupling Reactions Involving Allyl, Benzyl and Alkyl C‐H Bonds
Authors: Deng Guo‐Jun , Xiao Fuhong , Yang Luo
Published: March 2015

Review: 51 refs.
ChemInform Abstract: Supported Metal Hydroxides as Efficient Heterogeneous Catalysts for Green Functional Group Transformations
Authors: Yamaguchi Kazuya , Mizuno Noritaka
Published: March 2015

Review: 65 refs.
ChemInform Abstract: Reactions of S‐, N‐Ambident Nucleophiles with Polarized Ethylenes Giving Pyrimidines and 1,3‐Thiazines
Authors: Tarabova Denisa , Hanusek Jiri
Published: March 2015

Review: 97 refs.
ChemInform Abstract: Using Dispersion‐Corrected Density Functional Theory to Understand Supramolecular Binding Thermodynamics
Authors: Antony Jens , Sure Rebecca , Grimme Stefan
Published: March 2015

Review: 121 refs.
ChemInform Abstract: DNAzyme‐Based Biosensors and Nanodevices
Authors: Gong Liang , Zhao Zilong , Lv Yi‐Fan , Huan Shuang‐Yan , Fu Ting , Zhang Xiao‐Bing , Shen Guo‐Li , Yu Ru‐Qin
Published: March 2015

Review: 132 refs.
ChemInform Abstract: Enzyme‐Responsive Polymer Assemblies Constructed Through Covalent Synthesis and Supramolecular Strategy
Authors: Ding Yan , Kang Yuetong , Zhang Xi
Published: March 2015

Review: 60 refs.
ChemInform Abstract: Emerging Enzymes for ATP Regeneration in Biocatalytic Processes
Authors: Andexer Jennifer N. , Richter Michael
Published: March 2015

Review: 100 refs.
ChemInform Abstract: Opportunities for Microbial Electrochemistry in Municipal Wastewater Treatment ‐ an Overview
Authors: Modin Oskar , Gustavsson David J. I.
Published: March 2015

Review: 105 refs.
ChemInform Abstract: Polymer Composites for Thermoelectric Applications
Authors: McGrail Brendan T. , Sehirlioglu Alp , Pentzer Emily
Published: March 2015

Review: 131 refs.
ChemInform Abstract: Pickering Interfacial Catalysis for Biphasic Systems: From Emulsion Design to Green Reactions
Authors: Pera‐Titus Marc , Leclercq Loic , Clacens Jean‐Marc , De Campo Floryan , Nardello‐Rataj Veronique
Published: March 2015

Review: [recent examples of hybrid and composite amphiphilic materials for the design of interfacial catalysts in Pickering emulsions for industrially relevant biphasic reactions in fine chemistry, biofuel upgrading, and depollution; 87 refs.
ChemInform Abstract: Diketopyrrolopyrrole: Brilliant Red Pigment Dye‐Based Fluorescent Probes and Their Applications
Authors: Kaur Matinder , Choi Dong Hoon
Published: March 2015

Review: 51 refs.
RC/BTB2 is essential for formation of primary cilia in mammalian cells
Authors: Zhang Ling , Li Wei , Ni Jin , Wu Jinghua , Liu Junping , Zhang Zhengang , Zhang Yong , Li Hongfei , Shi Yuqin , Teves Maria E. , Song Shizheng , Strauss Jerome F. , Zhang Zhibing
Published: March 2015

RC/BTB2 is a binding partner of sperm associated antigen 16S (SPAG16S), which is a regulator of spermiogenesis in mice, a process during which sperm flagella are formed. The expression of Rc/btb2 is also regulated by multicilin, a protein that controls ciliogenesis. Given that mouse Rc/btb2 mRNA is not only expressed in tissues bearing motile cilia, but also in tissues without motile cilia, we investigated whether RC/BTB2 plays a role in the general process of ciliogenesis by studying two cell lines that have primary cilia, NIH3T3, and IMCD3. We discovered that the subcellular localization of RC/BTB2 in the NIH3T3 and IMCD3 cells encompasses the pathway for ciliogenesis. RC/BTB2 was found in the Golgi bodies and centrosomes, two key structures essential for normal ciliogenesis. Knockdown of Rc/btb2 gene expression in these cell lines disrupted ciliogenesis. The percentage of cells with primary cilia was significantly reduced in stable cell lines transduced with specific Rc/btb2 shRNA viruses as compared to the control cells. When cilia were formed in the knockdown cells, they were significantly shorter than those in the control cells. Knockdown of Rc/btb2 expression did not affect cell proliferation and the cell cycle. Exogenous expression of RC/BTB2 in these stable knockdown cells restored ciliogenesis. These findings suggest that RC/BTB2 is a necessary component of the process of formation of primary cilia in somatic cells, perhaps through the transportation of cargos from Golgi bodies to centrosomes for cilia assembling. © 2015 Wiley Periodicals, Inc.
Public health impact of achieving 80% colorectal cancer screening rates in the United States by 2018
Authors: Meester Reinier G. S. , Doubeni Chyke A. , Zauber Ann G. , Goede S. Luuk , Levin Theodore R. , Corley Douglas A. , Jemal Ahmedin , Lansdorp‐Vogelaar Iris
Published: March 2015

BACKGROUND

The National Colorectal Cancer Roundtable, a national coalition of public, private, and voluntary organizations, has recently announced an initiative to increase colorectal cancer (CRC) screening rates in the United States to 80% by 2018. The authors evaluated the potential public health benefits of achieving this goal.

METHODS

The authors simulated the 1980 through 2030 United States population of individuals aged 50 to 100 years using microsimulation modeling. Test‐specific historical screening rates were based on National Health Interview Survey data for 1987 through 2013. The effects of increasing screening rates from approximately 58% in 2013 to 80% in 2018 were compared to a scenario in which the screening rate remained approximately constant. The outcomes were cancer incidence and mortality rates and numbers of CRC cases and deaths during short‐term follow‐up (2013‐2020) and extended follow‐up (2013‐2030).

RESULTS

Increasing CRC screening rates to 80% by 2018 would reduce CRC incidence rates by 17% and mortality rates by 19% during short‐term follow‐up and by 22% and 33%, respectively, during extended follow‐up. These reductions would amount to a total of 277,000 averted new cancers and 203,000 averted CRC deaths from 2013 through 2030.

CONCLUSIONS

Achieving the goal of increasing the uptake of CRC screening in the United States to 80% by 2018 may have a considerable public health impact by averting approximately 280,000 new cancer cases and 200,000 cancer deaths within <20 years. Cancer 2015;121:2281–2285. © 2015 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
Interaction of Globular Plasma Proteins with Water‐Soluble CdSe Quantum Dots
Authors: Pathak Jyotsana , Rawat Kamla , Sanwlani Shilpa , Bohidar H. B.
Published: March 2015

The interactions between water‐soluble semiconductor quantum dots [hydrophilic 3‐mercaptopropionic acid (MPA)‐coated CdSe] and three globular plasma proteins, namely, bovine serum albumin (BSA), β‐lactoglobulin (β‐Lg) and human serum albumin (HSA), are investigated. Acidic residues of protein molecules form electrostatic interactions with these quantum dots (QDs). To determine the stoichiometry of proteins bound to QDs, we used dynamic light scattering (DLS) and zeta potential techniques. Fluorescence resonance energy transfer (FRET) experiments revealed energy transfer from tryptophan residues in the proteins to the QD particles. Quenching of the intrinsic fluorescence of protein molecules was noticed during this binding process (hierarchy HSA<β‐Lg <BSA, lower binding affinity for hydrophobic protein molecules). Upon binding with QD particles, the protein molecules underwent substantial conformational changes at the secondary‐structure level (50 % helicity lost), due to loss in hydration.