bluuebunny/crossref_metadata_2025 huggingface dataset:
Ansiedad y depresión en estudiantes de 12 a 18 años en un colegio de la ciudad de Quito – Ecuador
Authors: Castillo Buitrón Michelle Carolina , Morales Fonseca Cristhian Fabricio , Romero Vega Jimena Verónica , Villacís Jácome Juan Enrique
Published: January 2023

La presente investigación tiene como objetivo principal identificar niveles de ansiedad y depresión en estudiantes. Se basa en el enfoque cuantitativo de tipo descriptivo. Esta investigación se encuentra conformada por 50 estudiantes con rango de edades comprendidas entre 12 a 18, debido a que son consideradas las etapas más importantes del ser humano por los cambios significativos tanto en el aspecto físico, psicológico y social de los estudiantes. La ansiedad y depresión generan efectos netamente negativos en las vidas de las personas, especialmente en estudiantes ya que puede desencadenar bajo rendimiento académico, conductas violentas, problemas para establecer problemas interpersonales e incluso llegar al suicidio. Los instrumentos utilizados para medir estas variables fueron: Inventario de Ansiedad y Depresión de Beck, donde se logró observar cómo resultados que estudiantes se encuentran atravesando por una ansiedad moderada y no severa. Mientras que al momento de medir la depresión los estudiantes de 12 años presentan un alto índice de depresión severa.
Writing Comics in English as a Foreign Language Classis: A Didactic Sequence with Tertiary Students
Authors: Coutinho dos Santos Jardel , Rivadeneira Zambrano María Angélica , Gáleas Arboleda Gabriela
Published: January 2023

El reporte de esta experiencia muestra una secuencia didáctica puesta en práctica durante el periodo académico 2021-2022 con estudiantes de una institución superior pública en la provincia de Los Ríos, Ecuador, en las clases de inglés 1 (A1). El objetivo de esta secuencia didáctica fue motivar a dos grupos de estudiantes de la carrera de Educación Básica a escribir a través del uso de comics en las clases de inglés. En esta actividad participaron de 81 estudiantes (N=81). Esta secuencia tuvo una duración de tres semanas clase, un total de 12 horas. Debido a la Pandemia del Covid-19 los cursos fueron impartidos de manera online a través de la plataforma Zoom. Al finalizar la actividad, se usó un cuestionario como instrumento de recolección de datos. Los resultados demostraron efectos positivos en los estudiantes, como la motivación, concientización de su propio aprendizaje, y autonomía. Este estudio motiva a docentes a usar comics para mejorar la enseñanza de inglés en la educación superior y perfeccionar la competencia del idioma inglés.
Manajemen Pendidikan dalam Kajian Epistemologi
Authors:   Universitas Indraprasta PGRI, Yusuf Aditya Dedy , Nurmantoro Muh. Aripin ,   STKIP Al-Amin Indramayu, Saefullah Kamali Asep ,   STKIP Syekh Manshur, Saepul Mustakim Usep ,   STKIP Syekh Manshur, Nur Indriani Arina ,   STKIP Syekh Manshur
Published: January 2023

The purpose of writing this scientific article is to answer several problems including: 1) The definition and meaning of epistemology. 2) the basic concept of education management. 3) the function of education management. 4) Principles or General Principles of Education Management. 5) Organizational Divisions in terms of Education Management Epistemology. The writing of this scientific article uses a literature study or literature study approach by collecting various relevant literature sources. The results of the study show several things including: 1) Epistemology of education is understood in various ways according to the views of Idealism, Realism, Pragmatism and Existentialism. 2) Management functions include planning, organizing, directing, coordinating and controlling 3) Education management is divided into divisions so that the education management function can run effectively and efficiently.
Meningkatkan Minat Dan Hasil Belajar Ekonomi Menggunakan Aplikasi E-Learning Madrasah Materi Badan Usaha Pada Siswa Kelas X IPS 1 Madrasah Aliyah Negeri 1 Kota Tangeran Selatan Tahun Pelajaran 2020-2021
Authors:   MAN 1 Kota Tangerang Selatan, Yudi Sartono Agung
Published: January 2023

Tujuan penelitian ini adalah (1) menjelaskan pengaruh penggunaan e-learning madrasah terhadap minat belajar siswa pada materi badan usaha mata pelajaran ekonomi kelas X IPS.1 di MAN 1 Kota Tangerang Selatan. (2) menjelaskan pengaruh penggunaan e-learning madrasah terhadap hasil belajar siswa pada materi badan usaha mata pelajaran ekonomi kelas X IPS.1 di MAN 1 Kota Tangerang Selatan. Penelitian ini menggunakan metode kualitatif. Populasi dalam penelitian ini adalah siswa kelas X IPS.1 MAN 1 Kota Tangerang Selatan. Teknik pengumpulan data menggunakan angket, tes objektif, observasi, dan dokumentasi. Hasil penelitian yang telah dilakukan menyatakan bahwa: (1) terdapat pengaruh positif signifikan penggunaan e-learning madrasah, terhadap minat belajar siswa pada materi badan usaha mata pelajaran ekonomi kelas X IPS.1 di MAN 1 Kota Tangerang Selatan. Hal tersebut didukung oleh fakta-fakta sebagai berikut: (1) Minat belajar siswa dengan menggunakan media e-learning madrasah sebanyak 15%. Hasil tersebut ditunjukkan pada siklus 1 sebesar 58% (19 siswa) dan pada siklus 2 sebesar 73% (24 siswa); (2) Keaktifan siswa dalam mengikuti pembelajaran dengan media e-learning madrasah meningkat sebanyak 18%. Hasil tersebut ditunjukkan pada siklus 1 sebesar 61% (20 siswa) dan pada siklus 2 sebesar 79% (26 siswa); (3) Ketuntasan hasil belajar meningkat sebesar 12%. Hasil tersebut ditunjukkan pada siklus 1 sebesar 73% (24 siswa) dan pada siklus 2 sebesar 85% (28 siswa); (4) Keaktifan siswa dalam pembelajaran mengalami peningkatan terbesar dibandingkan dengan minat belajar, keaktifan dan ketuntasan hasil belajar siswa. Hal tersebut disebabkan siswa memberi respon yang positif terhadap tugas yang diberikan guru dengan aktif berdiskusi secara klasikal.
Analisis Promosi, Rotasi Dan Mutasi Kepala Sekolah SMA/SMK Di Provinsi Banten
Authors:   UIN Sultan Maulana Hasanuddin Banten, Zohriah Anis , Nasrudin Anas ,   UIN Sultan Maulana Hasanuddin Banten
Published: January 2023

Penelitian ini menggunakan jenis penelitian pustaka (library research), yaitu penelitian dengan serangkaian kegiatan yang berkenaan dengan metode pengumpulan data pustaka, membaca dan mencatat serta mengolah bahan penelitian. Penelitian pustaka (library research) merupakan penelitian yang objeknya dicari dengan berbagai informasi pustaka seperti buku, jurnal ilmiah, majalah, koran dan dokumen. Tujuan penelitian ini mendeskripsikan; (a)Landasan apa dalam perekrutan/pengangkatan kepala sekolah? (b) Bagaimana sistem rekrutmen dan seleksi yang dilaksanakan mampu mendapatkan calon kepala sekolah yang sesuai dengan yang diharapkan atau ideal?; (c) Bagaimana sistem penempatan hasil seleksi calon kepala sekolah?. Hasil penelitian menunjukkan bahwa proses promosi kepala sekolah SMA/SMK yang diselenggarakan oleh pemerintah Provinsi Banten melalui mekanisme yang telah ditetapkan oleh Permendikbud Ristek Nomor 40 Tahun 2021. Sementara rotasi dan mutasi kepala sekolah belum sepenuhnya mengacu kepada Permendikbud Nomor 6 Tahun 2018 tentang penugasan kepala sekolah pada satuan pendidikan yang diselenggarakan oleh pemerintah daerah dengan sistem periodesasi.
SPD am Wendepunkt
Authors: Stöss Richard
Published: January 2023

Ist der für viele unerwartete Erfolg der SPD bei der Bundestagswahl das Zeichen einer Trendwende oder nur ein Zwischenhoch? Das Ziel der vorliegenden Studie besteht zunächst darin, die externen und die internen Ursachen für den dramatischen Rückgang der Wahlergebnisse der SPD zwischen 1998 und 2017 von 40,9 Prozent auf 20,5 Prozent zu ergründen und eine Erklärung für den Last-Minute-Swing auf überraschende 25,7 Prozent bei der letzten Bundestagswahl zu finden. Untersucht wird erstens, ob die SPD bei ihrer Talfahrt nach 1998 eher Opfer von ihr nicht zu verantwortender widriger gesellschaftlicher Entwicklungen geworden ist oder ob sie das Debakel durch eigenverantwortliches (Fehl-)Verhalten selbst verursacht hat und zweitens, ob die überraschende Kehrtwende 2021 das Ergebnis günstiger Wettbewerbsbedingungen im Wahlkampf oder kluger strategischer Planungen der Partei(führung) war. Schließlich stellt sich die für die Praxis und für die Zukunft der SPD nicht unerhebliche Frage, wie die neuere Entwicklung zu bewerten ist: Handelt es sich bei dem plötzlichen Höhenflug um das Ende oder nur um eine Unterbrechung des Niedergangs der SPD oder deutet sich eine substanzielle Trendwende im Sinne einer politisch-programmatischen und personellen Neuausrichtung der Partei unter Olaf Scholz an?
Perspective Chapter: Critical Role of Hedgehog in Tumor Microenvironment
Authors: Li Xing-Guo , Yang Jer-Yen
Published: January 2023

Hedgehog (Hh) signaling is a highly conserved pathway that plays a pivotal role during embryonic development. Mounting evidence has implicated Hh signaling in various types of cancer. Accordingly, inhibition of aberrant Hh signaling continues to be pursed across multiple cancer types -with some success in certain malignancies. In addition, with the renaissance of antitumor immunotherapy, an in-depth understanding of the molecular mechanisms underlying how the multifaceted functions of Hh signaling shape immunologically suppressive tumor microenvironment might be the key to unlocking a new era of oncological treatments associated with a reduced propensity for the development of drug resistance. Here, we focus on the latest advances regarding the immunological effects of misregulation of Hh signaling on tumor immunity. We also review the current status of clinically approved Hh inhibitors and dissect the mechanisms of drug resistance. Finally, we discuss the potential clinical applications that harness the immunomodulatory effects of Hh signaling not only to circumvent drug resistance, but also to achieve durable efficacy following immunotherapies, thus ultimately resulting in improved patient outcomes.
Perspective Chapter: Evaluation of E-Learning Challenging Discourse – Prospects and Problems of Implementation
Authors: Alhamshary Yousreya
Published: January 2023

The concept of e-learning is very attractive as a new learning paradigm, the effect which will be a positive one to the development of education in developing countries especially Egypt. E-learning in Egypt is still facing a lot of problems and challenges that are not only technological but also social and cultural and other technical ones. This paper explores another possible reason—a mismatch between learning orientation and e-learning design in the form of inappropriate implementation of teaching or learning strategies during implementation. So, the purpose of this paper is, firstly, reflecting on the application of e-learning in the courses of university learners in Egypt; secondly, to review empirical studies on solutions to problems encountered in university stage in relation to e-learning; thirdly, to analyze the social and cultural prospects of e-learning application for Egyptian students. Some suggested ideas are discussed, and some reflections are presented about new technologies used. Still, there are some cultural and social aspects about e-learning implementation in Egypt. Major problems are lack of experience, cost of developing courses or weak infrastructure, and negative attitudes of some families.
The Role of the Internal Structure of Fabaceae Seeds in the Processes of Dormancy and Germination
Authors: Jara-Peña Enoc , Marín-Bravo Manuel
Published: January 2023

The germination processes of Fabaceae seeds are well studied based on physiological parameters. However, in many cases, especially in wild seeds, there is a predominance of dormancy processes that must be reversed to finally produce germination, generally applying scarification processes. In the anatomical studies of seeds, a certain conformation of the structure of the cover is appreciated, with a predominance of sclerenchymatic tissues and waxy covers that are the cause of the difficulty of the entry of water to produce the imbibition of the seed. Mechanical or chemical scarifications are usually recommended to produce effective scarification. The characterization of the anatomical details of the seed coat allows us to predict the appropriate scarification technique with which optimal seed germination can be obtained.
Toxic Heavy Metals in Soil and Plants from a Gold Mining Area, South Africa
Authors: Busuyi Raji Iyioluwa , Gertrude Palamuleni Lobina
Published: January 2023

The mining of mineral deposits abundant in South Africa has led to the release of toxic heavy metals into the environment. The aim of this study was to investigate heavy metal pollution from a gold mining area. The concentrations of arsenic, cadmium, lead, and zinc were analyzed in soil and plants found within 500 m and 1000 m radius of a gold mine established in North-West. The concentrations of these heavy metals were determined using Inductively Coupled Plasma Mass Spectrometry. The results showed that the concentrations of the studied heavy metals were all below the national and international threshold but higher than the concentrations found several kilometers away from the mining area, the natural background concentration. The results from the pollution load index shows that the topsoil is contaminated for the selected heavy metals. There was accumulation of the studied heavy metals in the studied Eragrostis hypnoides plant’s leaves and roots. In this study, it was revealed that zinc and cadmium bioaccumulated in the plant via the soil. These findings suggests that the consumption of agricultural products from farms within the 1 km radius of the mining site could be detrimental to the wellbeing of direct and indirect consumers.
Formulation by Design: An Overview
Authors: Das Ushasi , Kumar Panda Dilip , Mandal Sanchita
Published: January 2023

Quality is the most important and necessary attribute for pharmaceutical product development, and it has become the focus of regulatory bodies in order to approve safe, efficacious, stable, patient-compliance, and cost-effective drug delivery systems. QbD-based formulation development is discovered to be an immerging technique in this context. FbD is a formulation development concept that aims to create more effective, safe, robust, cost-effective, and patient-compliant drug delivery systems. This chapter will provide an overview of Formulation by Design (FbD), different terminologies, design of experiment (DoE) and quality by design (QbD), types of experimental design, QbD applications, and FbD methodology along with benefits.
Involvement of CRISPR-Cas Systems in Salmonella Immune Response, Genome Editing, and Pathogen Typing in Diagnosis and Surveillance
Authors: Gao Ruimin , Rae Frost Jasmine
Published: January 2023

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated cas genes (CRISPR-Cas) provide acquired immunity in prokaryotes and protect microbial cells against infection by foreign organisms. CRISPR regions are found in bacterial genomes including Salmonella which is one of the primary causes of bacterial foodborne illness worldwide. The CRISPR array is composed of a succession duplicate sequences (repeats) which are separated by similar sized variable sequences (spacers). This chapter will first focus on the CRISPR-Cas involved in Salmonella immune response. With the emergence of whole genome sequencing (WGS) in recent years, more Salmonella genome sequences are available, and various genomic tools for CRISPR arrays identification have been developed. Second, through the analysis of 115 Salmonella isolates with complete genome sequences, significant diversity of spacer profiles in CRISPR arrays. Finally, some applications of CRISPR-Cas systems in Salmonella are illustrated, which mainly includes genome editing, CRISPR closely relating to antimicrobial resistance (AMR), CRISPR typing and subtyping as improved laboratory diagnostic tools. In summary, this chapter provides a brief review of the CRISPR-Cas system in Salmonella, which enhances the current knowledge of Salmonella genomics, and hold promise for developing new diagnostics methods in improving laboratory diagnosis and surveillance endeavors in food safety.
Modulatory Effect of Neurotrophic Factors on the TRPV1 Expression: Possible Mechanisms Involved in the Antiepileptic Effect of Exercise
Authors: Navazesh Azam , Rasoolijazi Homa , Rahmani Ghazal , Bavi Saad , Vahabzadeh Gelareh , Soleimani Mansoureh , Karimzadeh Fariba
Published: January 2023

Background: Epilepsy is one of the most important diseases of the central nervous system, for which has no definitive treatment. Neurotrophic factors increase the survival of nerve cells and improve the treatment of neurological diseases. Identifying factors that affect the increase of neurotrophins in the brain is an important goal for brain health and function. Objectives: This study aimed to investigate the effectiveness of exercise on neurotrophic factors by influencing the expression of vanilloid receptor type 1 (TRPV1). Methods: Convulsions were induced by injecting pentylenetetrazol (PTZ; 35 mg/kg) five hours after exercise. Animals were divided into five groups: sham (Sham), seizure (PTZ), exercise (EX), exercise with seizure induction (EX+PTZ), and exercise before seizure induction (EX-PTZ). The exercise was 30 minutes of forced running on a treadmill, five days a week for four weeks. Results: The average percentage of NGF cells in the exercise groups (EX), exercise with seizure induction (EX+PTZ), and exercise before seizure induction (EX-PTZ), and GDNF in the exercise group with seizure induction (EX+PTZ) had a significant increase compared to the seizure group (PTZ). Also, TRPV1 activity in exercise groups (EX), exercise with seizure induction (EX+PTZ), and exercise before seizure induction (EX-PTZ) showed a significant increase compared to the seizure group (PTZ). Conclusions: Our findings suggested the possible antiepileptic and antiepileptogenesis effects of exercise through activation of neurotrophic factors and TRPV1 modulation.
Analysis of marketing communication policy in banking institutions of Ukraine
Authors: Zaslavska Olha
Published: January 2023

Marketing communications are an integral element of ensuring the bank's competitive position in the financial services market. In modern conditions it is not enough for financial institutions to develop a qualitatively new product, set an optimal price for it and choose effective distribution channels. Any financial institution must successfully operate the communication tools. Thus, the majority of the institution's communication costs are investments in the creation of intangible marketing assets: trademarks, relationships with consumers and other participants in the value chain. The implementation of the adopted communication strategy contributes to the development of organizational knowledge and a deeper understanding of the market, which allows the institution to increase the efficiency of the main business processes. For their part, these processes contribute to increasing the institution's potential to increase its shareholder value. In order to study the communication policy of Ukrainian banks, it was made a ranking of these institutions according to key financial and organizational indicators. Taking into account the analysis, the TOP-5 banks were selected for further research, which consists of an analysis of media activity of these commercial banks, website traffic indicators and their activity in social networks. Overall the following indicators were explored: number of messages about the banks on Facebook, in the printed and electronic media, on the websites of state authorities, on television and radio; the place of the bank's website by attendance, the average number of visits during one month, the average length of stay on the site, the average number of viewed pages and the bounce rate. As a conclusion it was emphasized on the need in further research of this topic in the field of anti-crisis communication management and there were outlined the directions of bank marketing in the period of an unstable economic situation. These directions will help to avoid a decline in sales in the difficult economic situation that is currently taking place in the Ukrainian financial market.
«Божественна пропорція» Луки Пачолі - розвиток бухгалтерської науки в Італії
Authors: Кіш Є.
Published: January 2023

Принципи «золотого перетину» використовуються в математиці, фізиці, біології, астрономії й інших науках, в архітектурі та мистецтвах. Вони лежать в основі архітектурних пропорцій багатьох чудових творів світового зодчества, головним чином античності і Відродження. На думку Луки Пачолі, навіть Бог використовував принцип золотого перерізу для створення Всесвіту. Золотий перетин, є феноменом, проявом гармонійності, пропорційності та симетрії формотворення в природі та мистецтві. Він втілює у собі континуальність, дискретність, симетричність, кількісні співвідношення подібності та контрасту, підпорядкованість і гармонійність форми. Золотий перетин (гармонійна поділ, поділ у крайньому і середньому відношенні) - поділ відрізка на дві частини таким чином, що більша його частина є середньою пропорційною між усім відрізком і меншою його частиною. Форма, в основі побудови якої лежать поєднання симетрії і золотого перетину, сприяє найкращому зоровому сприйняттю і появі відчуття краси і гармонії. Ціле завжди складається з частин, частини різної величини знаходяться в певному відношенні один до одного і до цілого. Принцип золотого перетину - вищий прояв структурної і функціональної досконалості цілого і його частин у мистецтві, науці, техніці і природі. Цю думку поділяли і поділяють багато видатних сучасні вчені, доводячи в своїх дослідженнях, що справжня краса завжди функціональна. Геніальний італійський математик Лука Пачолі, у часи середньовічного Ренесансу, написав першу книжку про золотий переріз, назвавши її «божественною пропорцією». Дослідження динаміки феномена золотого перетину дозволяє стверджувати, що даний принцип був протягом усього розвитку людства. В культурно-історичних позиціях епохи Відродження позначилася чітка тенденція до пошуку формальних регуляторів процесу життя та творчості. Гармонійні пропорції фігури людини, статуї, будівлі розглядали як неодмінну умову мистецького твору – відображення встановленої Божественної краси. Критерієм істини, з одного боку, стає божественне джерело, а з другого, величезну роль починає відігравати пропорційне співвідношення частин у формі.

Лука Пачолі знайшов застосування «золотого перетину» в бухгалтерському обліку, де найголовнішим вкладом в методологію було уявлення про цілісність системи та про те, що збіжність балансу є ознакою гармонії системи. Дана характеристика «Божественна пропорція».
ESG indikátorok a fenntarthatósági jelentésekben – mi lehet a szerepük a pénzügyi intézményeknek?
Authors: Gulyás Éva , Hajdu Tibor , Reizinger-Ducsai Anita
Published: January 2023

Az ESG szemlélet olyan vállalati-szervezetirányítási működést jelent, amely a fenntarthatóságot célzó törekvéseket, így a környezeti, társadalmi és vállalatirányítási szempontokat is figyelembe veszi a döntéshozatal során. Felmérésünk alapján a cégvezetők egyre fontosabb tényezőként tekintenek az általuk vezetett vállalat ESG szemlélettel való azonosulására. A megkérdezettek jelentős része úgy gondolja, hogy a jövőbeli sikeresség tekintetében meghatározóak lesznek a környezeti kockázatok, illetve az elmúlt években felértékelődött a társadalmi komponens szerepe is a vállalatok értékelése során. Összefoglaló leíró tanulmányunkban bemutatjuk az ESG értékelések főbb komponenseit, és megvizsgáljuk a szabályozói környezetet. Összesítjük a vállalatok értékelésében végbemenő változások jövedelmezőségi vélt vagy valós előnyeit, kiegészítve egyéb lehetséges előnyökkel. Kutatásunk fő témája az ESG értékelés megbízhatóságának mérése, hiszen megbízható adatok nélkül nem tudunk megfelelően nyilatkozni a valós jövedelmezőségi előnyökről sem. Hosszú távú célunk a szabályozói kör számára világossá tenni, hogy a jelenlegi értékelési, mérési szempontok nem megbízhatóak. Figyelembe véve az új CSRD irányelvet olyan megállapításokat teszünk, amely segíti a jogalkotókat az irányelv gyakorlati alkalmazásához kapcsolódó szabályozás kialakítása során. Kutatásunk alapját a jelenlegi követelményeknek megfelelő fenntarthatósági jelentések elemzése adta, továbbá vizsgáltuk az ESG minősítők gyakorlatát, majd ezeket összehasonlítottuk egymással. Foglalkoztunk a minősítők által nyilvánosságra hozott ESG indexek és a jövedelmezőség közötti kapcsolat vizsgálatával is. Jelen tanulmányunkban arra törekszünk, hogy összefoglaljuk az ESG indikátorok alkalmazásának anomáliáit, kiemelten foglalkozva a szabályozói környezettel. Célunk annak a bemutatása is, hogy a pénzügyi piac feltörekvő, innovatív eszközöket használó start-up-jai, vállalkozásai, a minősítők, illetve a befektetési szolgáltatók milyen új szerepben találhatják magukat.
THỰC TRẠNG THỰC HÀNH LIỆU PHÁP TẬP THỞ Ở NGƯỜI BỆNH PHỔI TẮC NGHẼN MẠN TÍNH
Authors: Lê Thị Thảo , Nguyễn Thị Kim Quyên , Chu Thị Giang Thanh
Published: January 2023

Đặt vấn đề: Báo cáo GOLD 2020 nhấn mạnh về vai trò nổi bật của vật lý trị liệu – phục hồi chức năng (VLTL-PHCN) bao gồm liệu pháp tập thở trong quản lý bệnh phổi tắc nghẽn mạn tính. Mục tiêu nghiên cứu: Đánh giá thực trạng thực hành tập thở trên người bệnh mắc bệnh phổi tắc nghẽn mạn tính. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang. Đánh giá dựa theo bảng kiểm liệu pháp tập thở trên 100 người bệnh bệnh phổi tắc nghẽn mạn tính đang điều trị tại Bệnh viện Đa khoa vùng Tây Nguyên và Bệnh viện Quận 11. Kết quả: Tỷ lệ nhóm tuổi ≥ 60 chiếm đa số (76%) và có tới 74% bệnh nhân là nam giới. Có 6 người bệnh không tham gia liệu pháp tập thở cơ hoành chủ động. 100% người bệnh tham gia liệu pháp tập thở chúm môi. Tỷ lệ người bệnh thực hiện đúng bước 2 trong liệu pháp tập thở chúm môi chiếm tỷ lệ cao nhất (99%). Tỷ lệ người bệnh thực hiện đúng bước 1 và 2 trong liệu pháp tập thở cơ hoành chiếm tỷ lệ cao nhất (80% và 84%). Kết luận: Liệu pháp tập thở là một trong những liệu pháp hô hấp hỗ trợ người bệnh hô hấp đặc biệt là người bệnh mắc bệnh phổi tắc nghẽn mạn tính. Nhưng thực trạng thực hành liệu pháp tập thở trên người bệnh phổi tắc nghẽn mạn tính còn thấp.
Cellular Telephone Use and the Cancer Risk: A systematic review and meta-analysis
Authors:   Southern Medical University, Guangzhou, China, Lin Anqi
Published: January 2023

Background: Over the past decades, the mobile phone has become a commonplace and an important communication tool for people in everyday life. However, there is much discussion surrounding the potential harm caused by the non-ionizing radiation (also referred to as radio frequency (RF) energy) emitted by mobile phones. This radiation, similar to that emitted by microwave ovens, is a controversial topic in academic circles, especially regarding whether the use of mobile phones increases or decreases the risk of certain tumors. Methods: To accumulate data, we conducted a comprehensive literature review (using the keywords: 'phone', 'telephone', 'cancer', 'tumor', 'carcinoma' and 'risk') of the following databases/search engines: PubMed/MEDLINE, Embase and Google-Scholar. The search embraces information published before May 2022. All case-control studies examining the relationship between the use of mobile phones and tumors were included. The included papers were evaluated and thoroughly analyzed and those with homogeneity were subjected to meta-analysis using R software. Results: Our initial search yielded 107 published articles. However, after application of our exclusion criteria, only 29 case-control studies were included in our final dataset. Meta analysis showed that regular use of mobile phones was associated with decreased risk of brain tumors, OR = 0.88 (95% CI: 0.84-0.91); however, the risk of head and neck cancer (HNC) increased with regular use of mobile phones, OR = 1.24 (95% CI: 1.08-1.42). In addition, regular use of mobile phones was associated with reduced risk of cancer in general, OR = 0.90 (95% CI: 0.87-0.94). Conclusion: Our findings do not suggest that regular use of mobile phones reduces the risk of cancer (especially brain tumors) or increases the risk of parotid gland tumors, necessarily. In the future study of mobile phones and cancer risk, we would recommend that researchers control for confounding factors in tumors, such as education and economics, and maintain a longer-term follow-up period.
Democratising conceptual art
Authors: Van Laeken Alexandra
Published: January 2023

In this paper I elaborate upon the elitist character of the mainstream theories on conceptual art. I show that the elitism is founded on wrong presumptions concerning the relation between artists and spectators. Working from the philosophy of Jacques Rancière, I reject the hierarchical structure present in the mainstream theories on conceptual art. Instead, I propose to take a ‘democratic turn’, as understood by Rancière. In such an outlook, the contribution of the spectator is revalued as equally active and creative as the contribution of the artist. The democratic turn has serious consequences for the theoretical foundation of conceptual art. We can no longer maintain that the conceptual work of art is solely the artist's idea, nor that the material appearance is negligible. Furthermore, the democratic alternative opens up conceptual art for a broader audience, while the very core of its practice remains intact, namely that the idea behind it is essential. But it adds an important caveat: what the idea represents is more than what the artist initially had in mind.
Another Outcry for Artistic Relevance
Authors: Gerwen Rob van
Published: January 2023

Editor's column
The influence of potential outcome on entrepreneurs' decisions to participate in Crowdfunding in Pakistan (Karachi)
Authors: Jamil Sobia , Shah Faiza , Khan Sherbaz , Imran Iqra
Published: January 2023

Crowdfunding is one of the best financial technology segments and has emerged as one of the leading platforms for startups to acquire funding. This paper identifies numerous benefits of Crowdfunding and investigates the influence of various factors, i.e., economic benefit, convenience and transaction process, social media, and social support, with the mediating effects of Motivation with gender moderation on an entrepreneur's perceived benefit of having the Intention to use the crowdfunding platform. The adapted questionnaire with a sample size of 240 is used in this study to survey the entrepreneurs of Pakistan by using a convenience sampling technique. Linear regression analysis tests the hypotheses with Smart Pls 3.0 software. The findings of this study confirmed that all direct relationships have a significant relationship with the Intention to use Crowdfunding. In contrast, the moderation of effects of gender was found to have an insignificant relationship with the Intention to use a crowdfunding platform. However, the contribution and significance of the study have also been discussed.
INTERNAL TESTING RESULT MANAGEMENT SYSTEM
Authors: Sukmana Rini Nuraini , Abdurrahman  , Khairiyyah Karina
Published: January 2023

One of the most important stages in the software development process is the testing phase. Tests on the software are performed with the aim of ensuring the functions of the software are working properly. PT. Solmit Bangun Indonesia as a company engaged in information technology services has obligations to it is clients to provide the best service by producing a software product that suits the needs. One effort made to ensure the software product has been running properly and as needed is the implementation of a system that can manage and monitor bugs in the software. Internal testing result management system is a system that helps the management and monitoring of data resolving issues (bugs) on software both in development stage and that have been implemented. The methodology used in this study is the method of by using Unified Modeling Language (UML) as a modeling language. For the development of the system using the prototype method. The programming language used in the design of this system is PHP Hypertext Preprocessor which is built using the framework code igniter (CI) with MySQL database. The thing that has been achieved in this research is has made a system that assist in managementand monitoring of solution of issues (bugs) in software at PT. Solmit Bangun Indonesia.
E-COMMERCE CERAMIC PRODUCTS
Authors: Abdurohim Uro , Islamiyanti Asri
Published: January 2023

The Fayyola Ceramics shop use a manual system so customer have to come directly to the store to buy or ask about products. If you only rely on the sales system in this way, it will take time so that customer have to wait and this has an impact on slow sales due to the absence of product promotion. With the web-based e-commerce application, it is hoped that it can help. Ceramic entrepreneurs market their product and consumers can access information on products being sold and place ordersfor products. In making this application using dreamweaver, PHP and MySQL as a database. The existence of this application is expected to expand the marketing reach of the Fayyola Ceramics Store and the UML method used to analiyze the design of e-commerce application.
PROSPECTIVE STUDENT DATA FOLLOW UP INFORMATION SYSTEM IN THE MARKETING DIVISION
Authors: Jayusman Yus , Jaenal Rahmat , Fitriani Wafa
Published: January 2023

The term follow up when it is called in indonesia means a follow up. Student is a term for someone who is currently pursuing or undergoing higher education in a college such as a high school, academy, and the most commin is a university. Marketing can be called as the spearhead of a company. So that companies that have good marketing will certainly experience significant development within a certain time. Follow up is needed to produce maximum data processing. Based on these problems, STMIK Bandung has a desire to make good use of information technology through the development of a follow-up system. Because the current follow-up data categorization system is not optimal for data management and reporting when needed. The software development model used is a waterfall and the data flow used is an activity diagram, the programming language is DBMS
Pengaruh Kerjasama Tim, Mentoring dan Motivasi Terhadap Kinerja Karyawan Frontliner Pada PT. Bank Central Asia, Tbk Kantor Cabang Utama Pekanbaru
Authors: Sitompul Silvia  Sari , Guntur Guntur
Published: January 2023

Penelitian ini bertujuan untuk menganalisis bagaimana pengaruh rekrutmen, pelatihan dan insentif terhadap kinerja karyawan. Kinerja Karyawan merupakan suatu prestasi kerja atau prestasi sesungguhnya yang dicapai oleh seseorang. Sampel yang digunakan dalam penelitian ini adalah seluruh karyawan front office PT Bank Central Asia, Tbk Cabang Sudirman. Penentuan sampel menggunakan metode purposive sampling dan teknik analisis data yang digunakan adalah regresi linier berganda dengan SPSS. Variabel Independen adalah rekrutmen, pelatihan dan insentif yang diuji pengaruhnya terhadap kinerja karyawan sebagai variabel dependen. Hasil penelitian ini menunjukkan bahwa rekrutmen dan pelatihan berpengaruh positif signifikan terhadap kinerja karyawan sedangkan insentif tidak memiliki pengaruh signifikan terhadap kinerja karyawan.
Pembuatan Sistem Informasi E-Office KUD Sawit Jaya Berbasis Web Dengan Menggunakan Framework Codeigniter 3
Authors: Nofiar.Am Andri , Kurnia Oktorina Fenty , Fitri Fitri , Ridwan Muhammad
Published: January 2023

Proses kegiatan dalam pengelolaan dokumen surat serta aktifitas perkantoran lain yang ada di KUD Sawit Jaya masih dilakukan secara manual. Dimana sekretaris akan mencatat setiap dokumen masuk maupun keluar kedalam buku agenda, kemudian sekretaris akan menggandakan dokumen tersebut untuk diserahkan kepada kepala dan dijadikan arsip. Mengingat sekretaris akan mendatangi ruangan kepala untuk menyerahkan dukumen dan meminta tanggapan yang kemungkinan kepala tidak berada ditempat sehingga surat masuk atau dokumen lainnya tidak mendapatkan respon dengan cepat. Solusi yang dilakukan untuk permasalahan ini yaitu dengan membuat sebuah sistem informasi e-office yang berbasis website yang dapat membantu proses penyimpanan dokumen dalam bentuk database dan setiap surat yang masuk akan lebih cepat mendapatkan tanggapan dari kepala sehingga tidak ada surat yang tidak mendapatkan respon. Dalam proses implementasi dilakukan dengan menggunakan bahasa pemograman PHP, phpMyAdmin untuk mengelola database di MySQL dan Framework Codeigniter 3
Proses Pembuatan Fermentasi Tongkol Jagung Pada Kelompok Ternak Sapi Potong di Kecamatan Donri-Donri, Kabupaten Soppeng
Authors: Ilham Rasyid  , Sirajuddin Sitti Nurani , Veronica Sri Lestari  , Jamila
Published: January 2023

Tanaman jagung menghasilkan limbah yang sangat berpotensi untuk dimanfaatkan menjadi pakan, khususnya hanya untuk ternak ruminansia karena kandungan seratnya tinggi. Salah satu limbah jagung yaitu tongkol jagung. Jika tongkol jagung difermentasi akan merupakan bahan pakan penting untuk sapi pada saat rumput sulit diperoleh, terutama pada musim kemarau. Kegiatan pembuatan fermentasi tongkol jagung sebagai pakan ternak dilakukan pada anggota kelompok ternak Tengnga-Tengngae di desa Labokong,Kecamatan Donri-Donri, Kabupaten Soppeng pada tanggal 4 Agustus 2022. Metode kegiatan yang dilakukan yaitu penyuluhan dan demontrasi langsung. Hasil kegiatan menunjukkan bahwa anggota kelompok Tengnga-Tenngae  yang berada di desa Labokong, Kecamatan Donri-Donri sangat antusias mengikuti kegiatan pembuatan fermentasi tongkol jagung sebagai pakan ternak
Pelatihan Komunikasi Efektif dan Pengembangan Kepribadian Bagi Karyawan Museum Balairung Siak
Authors: Mustaqimmah Nurul , Hanif Ahda Muhammad , Shinta Lestari Suci , Dini Restia Novi , Arif Muhammad , Fadhli Muhammad
Published: January 2023

Komunikasi efektif sangat berguna untuk mencegah atau mengatasi masalah. Komunikasi yang baik tentu akan meminimalisir terjadinya konflik. Kemampuan berkomunikasi dan pengembangan diri sangat erat kaitannya dengan pelayanan public. Pada analisis situasi ditemukan masalah kurang mampunya pengelola museum balaiurung mengemas pesan sehingga pesan dapat diterima dengan baik pula oleh pengunjung. Kegiatan pengabdian ini bertujuan untuk meningkatkan kemampuan komunikasi seluruh jajaran yang bertugas pada museum balairung Kabupaten Siak. Beberapa materi disampaikan secara berulang dan ditambah sesuai dengan kebutuhan peserta. Kegiatan ini mempunyai dampak positif yang terlihat pada akhir pertemuan diadakan sesi roleplay dan tanya jawab. Para peserta menunjukkan kemampuan berbicara di depan public dan mempraktikkan materi yang telah diberi. Selain itu sebanyak 80% peserta mengaku lebih percaya diri dalam menyampaikan pesan serta mengatur gestur setelah memahami materi yang diberikan.
Aplikasi Ricezzy Untuk Menghitung Irigasi Tanaman Padi Menggunakan Metode Fuzzy Mamdani
Authors: Fadila Shucy
Published: January 2023

Penelitian ini bertujuan untuk menganalisis permasalahan yang timbul apakah logika fuzzy mamdani dapat digunakan untuk memprediksi menghitung debit air irigasi pada tanaman sawah. Logika fuzzy sendiri merupakan salah satu metode untuk melakukan analisis sistem yang mengandung ketidak pastian. Pada penelitian ini digunakan metode mamdani atau sering juga dikenal dengan metode Min – Max. Perancangan sistem untuk mendapatkan output dilakukan dalam tahap – tahap (a) pembentukan himpunan fuzzy, (b) Aplikasi fungsi implikasi, (c) membentuk aturan – aturan, (d) penegasan (defuzzifikasi). Pada penelitian ini defuzzifikasi dilakukan dengan menggunakan metode centroid. Pada metode ini nilai defuzzyfikasi bergerak secara halus, sehingga perubahan pada himpunan fuzzy juga akan bergerak dengan halus. Dari hasil riset yang telah dilakukan dengan mencari suhu 10˚C, kelembapan 20 %, dan tinggi air 14 cm, dengan menggunakan metode fuzzy mamdani yaitu Banyaknya Debit Irigasi (y*)= 1.8823529411765 L/s/Ha.
Aplikasi Pendaftaran Mahasiswa Baru Menggunakan Metode Forecasting
Authors: Adam Adam
Published: January 2023

Peramalan (forecasting) merupakan alat bantu yang penting dalam perancangan yang efektif dan efisien. Peramalan adalah prediksi, proyeksi atau estimasi tingkat kejadian yang tidak pasti dimasa yang akan datang. Peramalan pada Universitas Abdurrab yang meramalkan jumlah calon mahasiswa baru yang mendaftar merupakan suatu sistem yang sangat di butuhkan pada universitas tersebut. Kerana universitas tersebut tidak mengetahui sebarapa banyak calon mahasiswa baru yang akan mendaftar pada tahun ajaran selanjutnya. Keberadaan metode foresting merupakan prosedur perbaikan pada peramalan terhadap objek pengamatan terbaru. Metode peramalan ini menitik beratkan pada penurunan prioritas secara eksponensial pada objek pengamatan sebelumnya. Dalam pemulusan eksponensial atau exponential smoothing terdapat satu atau lebih parameter. Pemulusan yang ditentukan secara eksplisit, dan hasil ini menentukan bobot yang dikenakan pada nilai observasi. Penelitian ini  mengenai prediksi jumlah mahasiswa baru telah banyak dilakukan sebelumnya. Seperti penelitian  yang melakukan penelitian tentang perancangan peramalan jumlah calon mahasiswa baru yang mendaftar dengan menggunakan algoritma Forecasting.
Perancangan Aplikasi Tuna Wicara Dan Tuna Rungu Dengan Metode Waterfall Berbasis Android
Authors: Rian Nanda
Published: January 2023

Abstrak - Bahasa isyarat merupakan salah satu alat komunikasi bagi penyandang tuna rungu dan tuna wicara, terlebih antara orang normal dengan penyandang dalam masyarakat yang lebih luas. Tetapi pada kenyataan, tidak semua orang dapat mengerti dan memahami maksud dan arti dari bahasa isyarat yang digunakan sehingga kurangnya pengetahuan orang normal tentang bahasa isyarat yang ada di Indonesia dan masih minimnya media pembelajaran digital yang efektif dan mudah dipahami Masyarakat penyandang tuna rungu tentunya mengalami kesulitan saat melakukan komunikasi sehari-hari, terutama bagi para siswa tuna rungu. Sejauh ini, mereka menggunakan bahasa isyarat SIBI dalam kegiatan belajar mengajar. SIBI merupakan jenis bahasa isyarat yang banyak digunakan pada lembaga pendidikan luar biasa. Namun disatu sisi, proses belajar mengajar dinilai masih kurang maksimal apalagi dimasa pandemi. Tujuan dari penelitian ini adalah untuk membangun sebuah aplikasi berbasis smartphone sebagai media pembelajaran tambahan pengenalan huruf alphabet dan kata bagi penyandang disabilitas tuna rungu serta memudahkan mereka untuk berkomunikasi dengan sesama. Aplikasi dibuat dengan menggunakan metode waterfall, dimulai dari analisis kebutuhan, perancangan, pembuatan hingga uji coba. Hasil aplikasi ini berupa aplikasi yang dapat menampilkan pembelajaran dan bermain yang dilengkapi dengan gambar Bahasa isyarat.
O Cartógrafo Mestiço: aproximações de Deleuze e Guattari com Martín-Barbero
Authors: Loose Ariadni , Petermann Juliana
Published: January 2023

Este artigo tem por propósito fazer uma aproximação entre as compreensões de Deleuze e Guattari (1995) sobre o método cartográfico e as aplicações de Jesús Martín-Barbero (2015) em sua teoria das mediações. Para isso, iremos analisar as definições de rizoma e as características da cartografia colocadas em prática no mapa das mediações, buscando responder a questão: Que aproximações podemos fazer entre as definições rizomáticas de Deleuze e Guattari (1995) e o segundo mapa das mediações de Martín-Barbero (2015)? Com essa análise teórico-metodológica, percebemos que estes possuem aproximação entre suas aplicações, com a presença das características cartográficas e de todos os princípios rizomáticos, definidos por Deleuze e Guattari (1995) no mapa das mediações de Martín-Barbero (2015).
A discursividade híbrida de coletivos midiativistas nas eleições de 2018
Authors: Ramalho Raul
Published: January 2023

Considerando a fluidez enunciativa possibilitada pelas tecnologias da informação e comunicação e pelos sites de redes sociais, este artigo analisa os discursos da Mídia Ninja e dos Jornalistas Livres, no processo eleitoral brasileiro de 2018, com o intuito de identificar marcadores textuais do midiativismo, jornalismo e discurso propagandístico. A partir das relações entre gêneros textuais e atividades socialmente reconhecidas, a metodologia utilizada foi baseada na Análise de Discurso Textualmente Orientada, que explica o discurso a partir da relação não hierárquica entre texto, prática discursiva e prática social. Os resultados mostram que os grupos apresentam um hibridismo discursivo (sendo que no corpus analisado o discurso propagandístico foi preponderante) e que a prática discursiva dos coletivos é melhor entendida sob o prisma da liberdade estético-enunciativa das mídias livres.
Cultura política y fake news en las elecciones presidenciales 2018 en Brasil
Authors: Castillo Sofia Vizcarra , Piccinin Fabiana , Castro Henrique Carlos de O. de
Published: January 2023

El artículo propone una reflexión sobre el surgimiento de las Fake News en el contexto de las últimas elecciones presidenciales y su relación con la cultura política brasileña. Proponemos pensar los desafíos para la comunicación que presenta este fenómeno considerando: 1) la crisis de confianza en las instituciones políticas y en los medios tradicionales de comunicación, así como el ascenso de los medios conectivos; 2) el descontento con el desempeño de la democracia y 3) las facilidades para que el ciudadano común publique y comparta contenidos en las redes, sin responsabilizarse por su veracidad, generando desregulación en el ambiente informativo.  Los resultados se basan en el análisis de la 7ma onda de la Encuesta Mundial de Valores realizada durante el año 2018 en Brasil.
The impact of TP53 and PTEN tumor suppressor genes on response to different breast cancer treatment modalities
Authors: Tanić Nikola , Dramićanin Tatjana , Ademović Nejla , Tomić Tijana , Murganić Blagoje , Milovanović Zorka , Nedeljković Milica , Tanić Nasta
Published: January 2023

Introduction. Breast cancer (BC) is the most frequent type of malignancy and the leading cause of cancer related death among women worldwide. BC is exceptionally heterogeneous disease and therefore distinct treatment modalities are necessary to address these differences. The aim of our study was to investigate the impact of TP53 and PTEN tumor suppressor genes (TSGs) inactivation on BC response to different treatment modalities and their possible cooperation, on post-operative BC samples. 

Methods. Patients were classified, based on applied adjuvant therapy, into four distinct groups: those that received hormonal therapy (HT) only, hormonal therapy combined with chemotherapy (HT/CHT), hormonal therapy combined with chemo and biological therapy (HT/CHT/H), and other systemic therapies that exclude HT. Functional inactivation of TP53 and PTEN TSG’s were studied by mutation, loss of heterozygosity (LOH) and hypermethylation analysis. 

Results. Our results revealed that TP53 gene was altered in 63 out of 90 specimens (70%), while the frequency of PTEN alterations was slightly lower, 54 out of 90 (60%). Simultaneous inactivation was detected in 43 tested samples (48%) with significant association between two analyzed TSGs. Further, we found that TP53 status has significant influence on patients’ therapy response. Contrary to this, no significance was found between mutational status of PTEN and various treatment modalities. However, significant association was found between the type of applied therapy and simultaneous alterations of these two TSGs (p = 0.00001). 

Conclusion. Patients with wtTP53 show significantly better therapy response regardless of the type of therapy, compared to carriers of altered TPp53 gene.