bluuebunny/crossref_metadata_2025 huggingface dataset:
Entre diálogos e imagens: Espaços e funções da escola pelo olhar de um grupo de estudantes concluintes do ensino fundamental
Authors: Zanelatto Elisângela Mara , Schwertner Suzana Feldens , Weber Daniela Maria
Published: September 2023

Que aprendizagens são possíveis na escola? Em quais espaços da escola se aprende? Esta discussão foi realizada com estudantes do 9° ano do Ensino Fundamental, em uma escola da rede pública de um município do interior do Rio Grande do Sul (RS), como parte da pesquisa "A escola e as novas configurações da contemporaneidade: a voz de estudantes concluintes do Ensino Médio e Fundamental" (MCTI/CNPq/Universal 14/2014), vinculada ao Mestrado em Ensino de uma universidade do RS. Os encontros promoveram debates, produção de fotografias e discussão das imagens produzidas, a partir da pergunta Qual a função da escola na contemporaneidade?. A discussão e o tratamento dos materiais foram conduzidos a partir da análise do discurso foucaultiano (2010, 2012, 2013). Os estudantes ressaltaram que é função da escola ensinar os conteúdos, mas que, também, é por meio dela que possuem as lembranças da infância, do tempo em que nela viveram, das amizades ali iniciadas. Indicaram que os espaços de aprendizagens podem envolver a sala de aula, o pátio externo, a quadra de esportes, os corredores, o parquinho, a biblioteca, e confirmaram que a escola permite construções para além do pré-estabelecido nos documentos escolares, deixando marcas na constituição dos estudantes.
Thromboelastographic and Gene Polymorphism Bimodality Detection for
Dual Antiplatelet Aggregation Therapy in Individuals with
Clopidogrel-resistant Symptomatic Intracranial Artery Stenosis
Authors: Liu Longlong , Li Yan , Li Ying
Published: September 2023

Background:

Recent research indicates that clopidogrel resistance is connected with a
patient's future ischemia risk, hence increasing the likelihood of recurrent ischemic cerebrovascular
disease. Thromboelastographic and clopidogrel gene polymorphism testing can be used to
see how a person responds to antiplatelet therapy and change the treatment plan accordingly.
This may be a good way to make antiplatelet aggregation therapy more effective and safer

Objective:

The objective of this study was to investigate the efficacy of dual antiplatelet aggregation
therapy in patients with symptomatic intracranial large artery stenosis being resistant to
clopidogrel tablets. The thromboelastographic and gene polymorphism bimodality detection
techniques were used to analyze the clopidogrel resistance influencing factors.

Methods:

89 patients with symptomatic intracranial large arterial stenosis who were admitted to
our hospital from February 2021 to February 2022 were selected, classified as large artery atherosclerotic
type by TOAST, and confirmed as having severe intracranial large arterial stenosis (70
% to 99 %) by magnetic resonance angiography (MRA), computed tomographic angiography
(CTA), and digital subtraction angiography (DSA). All patients were treated with dual antiplatelet
therapy with aspirin and clopidogrel, and thromboelastography and clopidogrel gene polymorphism
were monitored 1 week later.

Results:

44 of 89 patients were clopidogrel-resistant. Among 44 patients, 20 were ticagrelorresistant
and 24 were cilostazol-resistant. Clopidogrel had a resistance rate of 49.4%. The recurrence
of ischemic cerebrovascular disease in the three groups was statistically significant (P<0.05)
after 3 months of follow-up treatment, but bleeding (intracranial, gastrointestinal, respiratory, urinary,
and mucocutaneous) and dyspnea were not. The clopidogrel-resistant group had a higher
number of females, as well as higher levels of hypertension, diabetes, and platelet count than the
sensitive group (P<0.05), but there was no significant difference in age, smoking, alcohol consumption,
previous stroke, glycosylated haemoglobin, creatinine, or low-density cholesterol.

Conclusion:

Using thromboelastographic and gene polymorphism bimodality detection, we found
switching to ticagrelor antiplatelet aggregation therapy as better than switching to cilostazol in patients
with symptomatic intracranial large artery stenosis being resistant to clopidogrel tablets. The
results may be biased due to the study being a single-centre study and having a limited sample size.
Artificial Intelligence for Infectious Disease Surveillance
Authors: Sankar Sathish , Sankar Ganesh Pitchaipillai , Eswaramoorthy Rajalakshmanan
Published: September 2023

Artificial intelligence (AI) is a branch of science that mainly deals with
computers. It can store massive data through built-in programs that can accumulate the
required data and convert it into intellectual actions with a reason. In recent years, AI
has played a vital role in various governmental and non-governmental sectors such as
engineering, medicine and economics. The development of AI in the field of infectious
diseases is colossal with a spectrum of applications including pathogen detection,
public health surveillance, cellular pathways and biomolecules in host-pathogen
interactions, drug discovery and vaccine development. Similarly, early detection is the
key to controlling any disease outbreak. Systematic collection and analysis of data will
yield vital data on the required tools for controlling the outbreak situation. The
antibiotic stewardship program is being implemented in very few healthcare
institutions due to its intense cost and work. AI is used for tackling the rise in antibiotic
use and developing an algorithm that can effectively control the use of antibiotics along
with diagnostic and treatment measures.
Structural Bioinformatics and Artificial Intelligence Approaches in De Novo Drug Design
Authors: Sivakumar Dakshinamurthy , Wu Sangwook
Published: September 2023

De novo drug design is a computational technique to develop novel chemical
compounds from scratch without prior knowledge. Traditionally, structural
bioinformatics approaches used either structure-based or ligand-based design; the
former uses the active site information of the protein, and the latter uses known active
binders. Modern methods based on artificial intelligence help design de novo drugs in
less time by using pre-trained models. One of the major bottlenecks of the de novo drug
design is the synthetic feasibility of the active compounds, which is addressed using
AI-based methods that help reduce the time and cost of analysis of those compounds.
Recent success stories from several companies show the strength of the AI-based de
novo drug design programs, and many advances can be expected shortly.
AI-Based Energy Management for Domestic Appliances
Authors: Gopal Raj Murugananth , Alexis S. John , Manickavasagam A. , Reji R.
Published: September 2023

Energy conservation is the need of the hour for various reasons, including
the depletion of fossil fuels. The domestic sector is the major consumer of generated
electricity across the globe. Artificial Intelligence is a powerful decision-making tool.
Building AI-based techniques will be effective in conserving energy for domestic
appliances. The general framework of AI-based lighting, room comfort, refrigerator
and other load systems have been addressed in this chapter. The AI-based systems can
effectively manage the operation of these loads, thereby reducing energy consumption
Morphological and Structural Characterizations of Strontium in Strontium Sulphate as a Perceptive Factor in the Computational Method for the Forensic Analysis of Tool Paint by Non-destructive Analytical Studies
Authors: Sithi Asma B. , Palanimurugan A. , Cyril A. , Thangadurai S.
Published: September 2023

The morphological and structural characterization of strontium in strontium
sulphate in forensic analysis is highlighted in this chapter. Strontium sulphate is a
polymeric compound with structural similarities to barium sulphate. The best tool for
forensic applications is the SEM's non-destructive microscopic inquiry, which has been
utilized as a reference technique to support the study. This study further demonstrated
that the main screening of samples using the XRD does not require any special sample
preparation. Crystallite size and miller plane for specific peak values are computed
using computational data and statistical techniques to obtain accuracy in the forensic
investigation. In comparison to previous descriptions of X-rays as tool paintings in
forensic analysis, this paper is the one that receives the most citations. A thorough
study of these tool coatings might effectively connect an optimistic presumption to
particular crime scene locations.
Tuberculous Dactilitis in Young Male, a Rare Case
Authors: Yusdianto Adrian , Tantular Rezki , R. Sugiri Yani Jane , Rahayu Sartono Teguh , Rachma Erawati Dini , Setyo Yudhanto Hendy
Published: September 2023

Introduction : Chylothorax is an uncommon medical condition caused by the accumulation of chylous fluid in the pleural space. Chylothorax has no predilection for sex or age. The prevalence after various cardiothoracic surgeries is 0.2% to 1%. Mortality and morbidity rates are around 10%. Respiratory distress may occur due to compression of the lung by the accumulated fluid. Management and approaches to treating the condition require multidisciplinary therapy, starting from non-pharmacological, pharmacological, to interventional management.
Case Report : A 57-year-old Man patient was referred to the emergency room with chief complaint of shortness of breath. Reduced breathing sound on both lung fields. No previous history of cancer or thoracic surgery were found. X-ray examination had found bilateral pleural effusion. Thoracocentesis and pleural fluid analysis was performed with total of 6800 cc serosanguinous, whitish fluid was extracted from both of the lung. The patient was diagnosed with chylothorax. Lymphangiography and embolization was performed on the leak on left thoracic duct (T10) from right lymph node. Antibiotic was also given to treat the community acquired pneumonia that could be one of the possible etiology on this patient. Dietary modification with low fat diet and Ocreotide was also given to this patient as one of the treatment modalities.
Discussion : The diagnosis of Chylothorax on this patient was established based on pleural fluid analysis and evidenced by lymphangiography examination by the presence of a leak in the thoracic lymphatic duct. Various modalities to  diagnose this condition have been carried out with inconclusive results. Non-pharmacological, pharmacological and radiological interventions with embolization through lymphangiography are proven to be able to stop leaks and reduce symptoms in this patient.
Conclusion : Chyle leak to the pleural space may compress the lung and cause respiratory distress. Combinaton of thoracocentesis, embolization of the leakage, dietary intake modification and administration of ocreotide may help prevent further chylous fluid accumulation.
Laws of the Wild: The Malaysian legal framework on wildlife conservation
Authors: Mohamad Sirat Nur Irinah , Roslim Salmah , Abdullah Mohd Zulhelmey , Abu Bakar Syatirah
Published: September 2023

Wildlife conservation in Malaysia faces numerous threats, including poaching, trafficking, the impact of climate change, and deforestation. To address these issues, the Wildlife Conservation Act of 2010 has been enacted to regulate, protect, conserve, and manage wildlife in Malaysia. This paper examines the current Malaysian legal framework on wildlife conservation, issues, and challenges. The discussion adopts the doctrinal legal research analysis. The findings of this paper can provide the governments, policymakers, and conservationists to tackle this pressing issue and implement effective solutions to minimise its impact on Malaysia, including enhancing the legal framework, policies, and enforcement procedures.
Islamic Perspectives on Recognizing Opportunities: Insights from Malay-Muslim academic librarians
Authors: Sa’ari Haziah , Md Jali Jafalizan , Idrus Marlia
Published: September 2023

This paper aims to identify the antecedents of entrepreneurial competencies among Malay-Muslim academic librarians in Malaysian public universities. To collect qualitative data, ten academic librarians were interviewed in focus group discussions. The findings revealed that academic librarians' practices are influenced by their personal beliefs and knowledge of Islam, which have become ingrained in their Muslim way of life despite their lack of understanding of entrepreneurial competencies. These factors have a significant impact on librarians' cognitive processes, thus, on their entrepreneurial behavior. The findings suggest that it is pivotal to strengthen the personal beliefs and knowledge of academic librarians to be entrepreneurial.
Development of Wakf Fund in Public Higher Education Institutions
Authors: Mohd Roslan Nur Razan Izzati , Nor Muhamad Nasrul Hisyam , Che Yaacob Ahmad
Published: September 2023

In light of evolving socioeconomic factors, the annual rise in education costs presents a pressing concern. Johor Islamic Religious Council has appointed special trustees from the UTM Education Wakf Fund and UTHM Education Cash Wakf Fund to address this challenge. This paper aims to analyze the development of wakf funds as practiced by UTM and UTHM. The research methodology employed for this study encompasses content analysis and interviews, unveiling the systematic and effective management of wakf funds for education. Notably, enhancements are evident in fund accumulation, refined management strategies, and the proactive adoption of fundraising approaches. These findings underscore the institutions' commitment to mitigating the escalating cost of education while ensuring sustainable financial support for their student communities.
Service Quality on KPR iB Customer Satisfaction BRI Syariah Pekanbaru
Authors: Zulkifli Zulkifli , Hamzah Zulfadli , Alfani Mufti Hasan , Arif Muhammad
Published: September 2023

This study examines the effect of service quality on KPR iB customer satisfaction at the BRI Syariah Pekanbaru Branch. It was designed as a descriptive quantitative study using simple linear regression analysis. The population in this study was all customers of KPR iB at the BRI Syariah Pekanbaru Branch, amounting to a total sample of 92 respondents. A questionnaire was distributed to obtain the data. The results showed that service quality significantly affected customer satisfaction, with a significance value of 0.000 and a T-count value of 4.806.
Non-alcoholic fatty liver disease, cardiovascular system and kidney function in young adults
Authors: Chulkov V. S. , Pankova E. D. , Krasnopeeva N. D. , Chulkov Vl. S.
Published: September 2023

Over the past four decades, non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease, believed to affect more than 25% of adults worldwide. Unless specific testing is done to detect NAFLD, the disease is typically silent until advanced and potentially irreversible liver impairment occurs. NAFLD is associated with a higher risk of cardiovascular and kidney dysfunction, independent of obesity, type 2 diabetes, and other common risk factors. However, the mechanisms underlying this association remain largely unexplored. An increase in the incidence of NAFLD among young individuals is emphasized. However, despite the global prevalence of NAFLD throughout the world, prevalence among young remains unclear. The purpose of this review is to analyze the main cardiometabolic risk factors and NAFLD and association with cardiovascular disease and kidney dysfunction in young adults.
Pharmacological aspects of cannabinoids
Authors: Safronenko A. V. , Saenko N. Yu. , Zemliakova V. P. , Kvaratskheliia S. K. , Dolnikova M. V.
Published: September 2023

This review presents recently available information on the properties of endogenous and exogenous cannabinoids, their possible mechanisms of action and effects. The article reflects foreign experience in the use of cannabinoid preparations for the recommended indications, as well as possible promising effects for the expansion of their clinical use.
Comparative characteristics of patients with arterial hypertension with positive and negative reactions to salt load at night time
Authors: Skibitskiy V. V. , Fendrikova A. V. , Vasilyev V. Y.
Published: September 2023

Objective: comparison of peripheral and central blood pressure, vascular wall stiffness and glomerular filtration rate in patients divided into salt-sensitive and salt-resistant based on the dynamics of blood pressure during night time after salt loading.

Materials and methods: the study included 180 patients with arterial hypertension: 96 men (53%) and 84 (47%) women, median age 59 (56-64) years. Salt sensitivity was assessed according to the method of V.I. Kharchenko with distribution into groups according to the results of blood pressure dynamics at night. Peripheral and central blood pressure, vascular stiffness, and glomerular filtration rate were compared.

Results: in 61% of salt resistant patients, there was a sufficient decrease in blood pressure during nocturnal sleep — the “dipper” profile, while in the group of salt sensitive patients, the decrease in blood pressure was sufficient only in 48%. Glomerular filtration rate was also higher in salt resistant patients compared to salt sensitive: 76,5 ml/min./1.73m2 versus 68 ml/min./1,73m2.

Conclusion: arterial hypertension is more severe in salt sensitive patients, which was reflected in the intergroup comparison of peripheral and central blood pressure, vascular stiffness, and excretory function of the kidneys. Assessment of salt sensitivity at night may be useful in identifying high-risk groups of patients requiring the most careful monitoring and “aggressive” antihypertensive therapy.
Codiotoxicity of anthraciclines and the possibilities of its correction
Authors: Kanorskii S. G. , Pavlovets V. P.
Published: September 2023

Due to the increased effectiveness of oncology treatments, cardiovascular disease, including chronic heart failure, is a major cause of morbidity and mortality in cancer survivors, limiting their life expectancy. Screening of 4700 literary sources from the databases "Scopus", "Web of Science", "PubMed / MedLine", "The CochraneLibrary" was carried out for the keywords "anthracycline-induced cardiotoxicity", "cardiooncology", "cancer therapy-related cardiac dysfunction", "sacubitril/valsartan" for the last 10 years. The review, based on the analysis of highly cited articles, outlines the current understanding of the cardiotoxicity of anthracyclines, its mechanisms and possibilities for correction, including the use of sacubitril/valsartan.
Explorando las competencias conceptuales básicas: Validez de contenido de un cuestionario sobre Radiología Oral y Maxilofacial
Authors: Flores-Girón Hazaria , Paz Claudinne , Paz-Maldonado Eddy
Published: September 2023

El objetivo de la presente investigación fue validar por contenido un cuestionario sobre las competencias conceptuales básicas de la Radiología Oral y Maxilofacial (ROMF). El estudio fue mixto con diseño descriptivo transversal, interpretativo y explicativo secuencial. Participaron 5 docentes latinoamericanos especialistas en ROMF, seleccionados mediante una muestra no probabilística intencional. Los datos cuantitativos y la información cualitativa se recolectaron en una matriz de validación. Para valorar cada uno de los criterios de evaluación se utilizó una escala Likert con cinco elementos de valoración siendo “totalmente en desacuerdo” el de menor valor (1%) y “totalmente de acuerdo” el mayor (5%). Los resultados cuantitativos alcanzados en los criterios de validación fueron: redacción de la interrogante 3,6%, coherencia del contenido 4,4%, comprensión del contenido 4,3% y secuencia-ubicación de la interrogante 4,6%. Con relación a los resultados cualitativos, se indicó: a) mejorar la redacción, b) especificar el tipo de toma radiográfica oral y c) considerar las regulaciones nacionales e internacionales en el planteamiento de las interrogantes. En conclusión, el cuestionario sobre las competencias conceptuales básicas de ROMF ha alcanzado la validez por contenido obteniendo un promedio de 4,2%. La siguiente etapa consistirá en aplicar una prueba piloto para lograr la confiabilidad de este instrumento.

Palabras Clave: Competencias conceptuales básicas, Odontología, Radiología Oral y Maxilofacial, Validez de contenido.
Estrategia educativa nutricional para enfermedades crónicas no transmisibles de personas privadas de la libertad
Authors: Calvopiña Rea Joffre Andrés , Inca-Torres Alberto Renato , Urbina-Salazar Anabell del Rocio , Cisneros Rea Encis Cristian
Published: September 2023

Los centros penitenciarios además de brindar ciertos derechos deben ofrecer protección y promoción de salud y la rehabilitación de las personas. Se realizó una investigación cuasiexperimental con 278 personas privadas de la libertad del pabellón de máxima seguridad del Centro de Rehabilitación Social Cotopaxi - Ecuador. Se estableció una estrategia promocional dirigida al estado nutricional. Mediante un muestreo probabilístico de tipo aleatorio simple se estableció una muestra de 163 individuos. Las acciones planificadas se implementaron durante cuatro meses, midiendo las variables de interés antes y después de la aplicación. El promedio de edad de los participantes fue de 38 a 56 años, la mayoría se autoidentificaron como mestizos (46,63%) y con un nivel escolar primaria (50,1%). El 53,37% no padecía de enfermedades crónicas no transmisibles. Las variables medidas durante el pretest y el postest mostraron diferencias significativas entre ambos momentos con valores coincidentes de p=0,02. El resultado de la estrategia promocional referente al buen estado nutritivo que se implementó quedó establecida a través de la prueba de McNemar, que permitió determinar cambios en el consumo de alimentos más saludables, la ejercitación física regular y el alcance de un índice de masa corporal dentro de los parámetros normales.
Palabras Clave: Estrategias; Promoción de la Salud; Estado Nutricional.
Perspectives on the COVID-19 Vaccination Rollout in 17 Countries: Reflexive Thematic and Frequency Analysis Based on the Strengths, Weaknesses, Opportunities, and Threats (SWOT) Framework
Authors: Kopilaš Vanja , Nasadiuk Khrystyna , Martinelli Lucia , Lhotska Lenka , Todorovic Zoran , Vidmar Matjaz , Machado Helena , Svalastog Anna Lydia , Gajović Srećko
Published: September 2023

Background

As the SARS-CoV-2 virus created a global pandemic and rapidly became an imminent threat to the health and lives of people worldwide, the need for a vaccine and its quick distribution among the population was evident. Due to the urgency, and on the back of international collaboration, vaccines were developed rapidly. However, vaccination rollouts showed different success rates in different countries and some also led to increased vaccine hesitancy.

Objective

The aim of this study was to identify the role of information sharing and context sensitivity in various vaccination programs throughout the initial COVID-19 vaccination rollout in different countries. Moreover, we aimed to identify factors in national vaccination programs related to COVID-19 vaccine hesitancy, safety, and effectiveness. Toward this end, multidisciplinary and multinational opinions from members of the Navigating Knowledge Landscape (NKL) network were analyzed.

Methods

From May to July 2021, 25 completed questionnaires from 27 NKL network members were collected. These contributors were from 17 different countries. The responses reflected the contributors’ subjective viewpoints on the status and details of the COVID-19 vaccination rollout in their countries. Contributors were asked to identify strengths, weaknesses, opportunities, and threats (ie, SWOT) of the respective vaccination programs. The responses were analyzed using reflexive thematic analysis, followed by frequency analysis of identified themes according to the represented countries.

Results

The perspectives of NKL network members showed a link between organizational elements of the vaccination rollout and the accompanying societal response, both of which were related to strengths and weaknesses of the process. External sociocultural variables, improved public communication around vaccination-related issues, ethical controversies, and the spread of disinformation were the dominant themes related to opportunities and challenges. In the SWOT 2×2 matrix, Availability and Barriers emerged as internal categories, whereas Transparent communication and promotion and Societal divide emerged as key external categories.

Conclusions

Inventory of themes and categories inspired by elements of the SWOT framework provides an informative multidisciplinary perspective for effective implementation of public health strategies in the battle against COVID-19 or any future pandemics of a similar nature.
Correction: Technology-Assisted Cognitive Motor Dual-Task Rehabilitation in Chronic Age-Related Conditions: Systematic Review (Preprint)
Authors: Tuena Cosimo , Borghesi Francesca , Bruni Francesca , Cavedoni Silvia , Maestri Sara , Riva Giuseppe , Tettamanti Mauro , Liperoti Rosa , Rossi Lorena , Ferrarin Maurizio , Stramba-Badiale Marco
Published: September 2023

BACKGROUND

Cognitive-motor dual-task (CMDT) is defined as the parallel processing of motor (eg, gait) and cognitive (eg, executive functions) activities and is an essential ability in daily life. Older adults living with frailty, chronic conditions (eg, neurodegenerative diseases), or multimorbidity pay high costs during CMDT. This can have serious consequences on the health and safety of older adults with chronic age-related conditions. However, CMDT rehabilitation can provide useful and effective therapies for these patients, particularly if delivered through technological devices.

OBJECTIVE

This review aims to describe the current technological applications, CMDT rehabilitative procedures, target populations, condition assessment, and efficacy and effectiveness of technology-assisted CMDT rehabilitation in chronic age-related conditions.

METHODS

We performed this systematic review, following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, on 3 databases (Web of Science, Embase, and PubMed). Original articles that were published in English; involved older adults (>65 years) with ≥1 chronic condition and/or frailty; and tested, with a clinical trial, a technology-assisted CMDT rehabilitation against a control condition were included. Risk of bias (Cochrane tool) and the RITES (Rating of Included Trials on the Efficacy-Effectiveness Spectrum) tool were used to evaluate the included studies.

RESULTS

A total of 1097 papers were screened, and 8 (0.73%) studies met the predefined inclusion criteria for this review. The target conditions for technology-assisted CMDT rehabilitation included Parkinson disease and dementia. However, little information regarding multimorbidity, chronicity, or frailty status is available. The primary outcomes included falls, balance, gait parameters, dual-task performance, and executive functions and attention. CMDT technology mainly consists of a motion-tracking system combined with virtual reality. CMDT rehabilitation involves different types of tasks (eg, obstacle negotiation and CMDT exercises). Compared with control conditions, CMDT training was found to be pleasant, safe, and effective particularly for dual-task performances, falls, gait, and cognition, and the effects were maintained at midterm follow-up.

CONCLUSIONS

Despite further research being mandatory, technology-assisted CMDT rehabilitation is a promising method to enhance motor-cognitive functions in older adults with chronic conditions.
mHealth Technology Experiences of Middle-Aged and Older Individuals With Visual Impairments: Cross-Sectional Interview Study (Preprint)
Authors: Choi Soyoung , Sajib Md Refat Uz Zaman , Manzano Jenna , Chlebek Christian Joseph
Published: September 2023

BACKGROUND

Current mobile health (mHealth) technology is predominantly designed with a visual orientation, often resulting in user interfaces that are inaccessible to visually impaired users. While mHealth technology offers potential for facilitating chronic illness management and enhancing health behaviors among visually impaired older populations, understanding its usage remains limited.

OBJECTIVE

This qualitative research aimed to explore the mHealth technology experiences of middle-aged and older individuals with visual impairments including the accessibility and usability issues they faced.

METHODS

The qualitative exploration was structured using the mHealth for Older Users framework. Cross-sectional interviews were conducted via Zoom between June 1 and July 31, 2023, using an interview protocol for data collection. A thematic analysis approach was employed to analyze the transcribed interview scripts.

RESULTS

Of the 7 participants who took part in the Zoom interviews, 3 were men and 4 were women, with ages ranging from 53 to 70 years. Most participants adopted mHealth apps and wearable devices for promoting health. They exhibited 3 distinct adoption patterns. Seven themes were emerged from the perceived challenges in using mHealth technologies: (1) a scarcity of accessible user manuals, (2) user interfaces that are not visually impaired-friendly, (3) health data visualizations that are not accessible, (4) unintuitive arrangement of app content, (5) health information that is challenging to comprehend, (6) cognitive overload caused by an excess of audible information, and (7) skepticism regarding the accuracy of health records. mHealth technologies seem to positively affect the health and health management of participants.

CONCLUSIONS

Design considerations for mHealth technologies should consider individuals’ disabilities and chronic conditions and should emphasize the importance of providing accessible manuals and training opportunities when introducing new mHealth solutions.
Efektifitas Yoga dan Hipnoterapi terhadap Tekanan Darah pada Wanita Usia Subur (WUS) Penderita Hipertensi
Authors: Juniartati Erni , Fittarsih Niya , Ernawati Ernawati
Published: September 2023

Latar   Belakang: Hipertensi seringkali dikenal dengan “The Silent Killer” karena sering tanpa keluhan, serta mampu menyebabkan kematian. Hipertensi dengan tidak adanya penanganan mampu mendatangkan kerusakan target organ dan komplikasi. Salah satu penanganan untuk penderita hipertensi yaitu dengan terapi yoga dan hipnoterapi.Tujuan: Memberikan penjelasan akan dampak yang diberikan oleh yoga dan hipnoterapi terhadap tekanan darah untuk penderita hipertensi grade I.Metode: Riset ini menggunakan eksperimen semu/quasi eksperimental dengan rancangan pretest and posttest with control group. Ada dua kelompok yang dipilih dengan non-random yakni kelompok kontrol serta kelompok intervensi. Sampel berjumlah 32 orang penderita hipertensi kategori prahipertensi dan hipertensi ringan.Hasil: Uji statistik menunjukkan tekanan darah sistolik dan diastolic mengalami pengurangan yang lebih besar di kelompok intervensi jika dibandingkan dengan kelompok kontrol (berturut-turut 19,75±6,485 vs 14,00±8,326 dan 16,75 mmHg vs 12,50 mmHg).Kesimpulan: Latihan yoga dan hipnoterapi efektif dalam melakukan penurunan pada tekanan darah sistolik jug diastolik.
Advocating Community Economic Resilience Framework in Kemadang Food Barn, Gunungkidul, Yogyakarta: Accentuating the Social Capital Perspective
Authors: Christanti Rossalina , Manik Hardo Firmana Given Grace , Ariestanti Catarina Aprilia
Published: September 2023

Agriculture is claimed as Indonesia’s strategic pillar sector. The existence of a community-based enterprise with a traditional business model is often seen as a weakness, while social capital is a strength to thrive. However, a well-managed conventional business model can become one of the foundations of a sustainable livelihood. This community service program wass carried out with the Artha Mandiri Group, which is domiciled in Kemadang Village, Gunungkidul, Special Region of Yogyakarta. This program aimed to increase the economic resilience of group members by empowering and growing business capabilities with their social capital as their fundamental strength. The empowerment method used in this program was Participatory Action Learning and Action Research (PALAR), which is considered an effective tool for strategically transforming paradigms. This method focused on a balance between progressive, collaborative practice accompanied by an action research foundation. The 6-month program has resulted in collaborative business competency learning practice for group members, emphasizing different processing methods to produce business line diversification. This group made flour from land-owned rice paddy harvests with the same quality as commercially produced. This achievement can also have an impact on business cost efficiency.
Water Conservation-Based Ecotourism Development for Sustainable Local Economic Development and Supporting the Borobudur National Tourism Strategic Area (KSPN)
Authors: Sartohadi Junun
Published: September 2023

The area around the Borobudur Temple area needs development so that it can become a tourism buffer area. This development will align with and answer the challenge of establishing Borobudur as a National Tourism Strategic Area (KSPN). Several areas in the Borobudur KSPN that fall into the Menoreh hills have high potential as natural tourist destinations, especially viewpoint and spring. Development is directed towards conservation-based tourism with educational content to increase the selling value. Giripurno Village is one of the Borobudur KSPN villages located in the Menoreh hills and has a potential tourism support infrastructure. The development is carried out by structuring the spring area as a tourist attraction to complement the activities of guests staying at the homestay. The spring area is laid out using lightweight, flexible, yet solid designs and building materials. The existence of spring objects that are arranged sustainably will provide additional activities for visiting tourists. In addition, professional management of each tourism infrastructure will further increase the existing tourism and economic potential
Safety Test for Ethanolic Neem Leaf (Azadirachta indica A. Juss.) Extract on Male Mice (Mus musculus L) Renal Structure
Authors: Lestari Ayu Dwi , Sitasiwi Agung Janika , Isdadiyanto Sri
Published: September 2023

Neem leaves (Azadirachta indica A. Juss.) are often used as traditional medicine because they contain bioactive compounds such as azadirachtin, nimbidin and nimbolides. Consumption of traditional medicines for long periods can cause side effect on kidney. This study aims to find out the histological structure of glomerular and proximal tubular in the male mice (Mus musculus L.)  kidneys after exposure to the ethanolic of neem leaves extract. Completely Randomized Design (CRD) consists of 2 treatment groups with 15 replications was used in this study. The first group is K (only treated with aquadest) and P group (treated by ethanolic neem leaves extrcat at the dosage 14 mg/ kg body weight). The treatment were given orally with a volume of 0.2 mL for 21 days. Feeding and drinking were carried out ad-libitum. At the 22 days, kidney was isolated, weighted and made for histological processed with 5 μm in thickness using paraffin method with Hematoxylin and Eosin staining. The variables observed in this study were kidney weight, water consumption, glomerular diameter, thick of Bowman capsule, diameter of proximal tubule and lumen diameter. Data were analyzed using the t test with a confidence level of 95%. The results of the analysis showed that the treatment has no significant effect (p> 0.05) to kidney weight, water consumption, glomerular diameter, thick of Bowman capsule, diameter of proximal tubules and lumen diameter. The study showed that the use of ethanolic neem leaves extract for 21 days still safe to be use as a traditional medicine.
Kejadian Fascioliasis pada Sapi Perah di Kecamatan Tegalombo, Kabupaten Pacitan
Authors: Arisona Alek , Indarjulianto Soedarmanto , Sugiyanto Catur , Pertiwiningrum Ambar , Prastowo Joko , . Yanuartono , Nururrozi Alfarisa , Wuri Margaretha Arnita , Prabowo Teguh Ari
Published: September 2023

Fascioliasis adalah penyakit cacing hati yang dapat menyerang sapi dan sangat merugikan, karena dapat menurunkan produktivitas. Peternakan sapi perah di Tegalombo, Pacitan merupakan peternakan rakyat yang pengelolaannya banyak melibatkan perempuan. Penelitian ini bertujuan mengidentifikasi fascioliasis pada sapi perah di kecamatan Tegalombo, kabupaten Pacitan. Sebanyak 50 ekor sapi perah digunakan sebagai sampel di dalam penelitian ini. Semua sapi diperiksa secara fisik, diambil fesesnya dan diperiksa adanya telur cacing Fasciola sp. Hasil pemeriksaan fisik sapi secara klinis menunjukkan bahwa semua sapi pada penelitian ini menunjukkan kondisi umum normal, nafsu makan baik, serta tidak ada abnormalitas yang signifikan pada semua bagian tubuh, sehingga dinyatakan sehat secara fisik. Hasil pemeriksaan sampel feses didapatkan adanya telur cacing Fasciola sp. pada 2 dari 50 ekor sapi (4%), sedangkan 48 ekor sapi lainnya (96 %) tidak ditemukan telur cacing. Kesimpulan dari peneltian ini adalah kejadian fascioliasis pada sapi perah di Tegalombo, kabupaten Pacitan rendah. Pemeriksaan secara periodik terhadap kemungkinan fascioliasis perlu dilakukan, sebagai langkah penanggulangan fascioliasis di daerah tersebut.
Case Report: Diagnosis and Therapy Technique for Dirofilariasis – Ehrlichiosis Coinfection in a Domestic Dog
Authors: Elviyanti Joan , Mihardi Arief Purwo , Esfandiari Anita , Akbari Rizal Arifin
Published: September 2023

Multiple pathogenic agents, such as dirofilariasis and ehrlichiosis coinfection in the dog, cause coinfection disease. This paper aims to elucidate the diagnosis and therapy technique of dirofilariasis and ehrlichiosis coinfection disease in a dog. The owner brought a 4-year-old female dog named Lua to Rvet Clinic Tajur Halang Bogor with complaints of always painting when doing activities and lying down. The dog was just adopted one month from the shelter with many ticks and mosquitoes in the cage. The dog was diagnosed with dirofilariasis and ehrlichiosis by physical examination and laboratory tests. The laboratory tests included radiography, haematology, blood smear, and antigen test by SNAP® 4Dx® Plus Test (IDEXX, US). The dog was given doxycycline 10 mg/kg BW BID orally for three weeks, vitamin B12 0.025mg/kg BW BID orally for three weeks, furosemide 2 mg/kg BW SID orally for one week, Coenzyme-Q10 SID orally for three weeks, and selamectin topical drop every month for three months. A blood smear on the 21st day after therapy did not show microfilariae in 20 hpf with three repetitions. It means the therapy combinations are used effectively to reduce microfilariae and maintain the clinical sign of a dog due to dirofilariasis accompanied by ehrlichiosis.
Identifikasi Protozoa Gastrointestinal pada Orangutan Sumatera (Pongo abelii) dan Orangutan Kalimantan (Pongo pygmaeus) di Taman Satwa Sumatera Utara
Authors: Anggraini Ferina , Hanafiah Muhammad , Rahmi Erdiansyah , Athaillah Farida , Helmi Teuku Zahrial , . Zainuddin
Published: September 2023

Infeksi protozoa merupakan salah satu penyakit parasitik yang umumnya bersifat kronis serta menyebabkan penurunan berat badan. Penelitian ini bertujuan untuk mengetahui protozoa gastrointestinal yang menginfeksi orangutan sumatera (Pongo abelii) dan orangutan kalimantan (Pongo pygmaeus) yang berada di Taman Satwa Sumatera Utara serta protozoa dari genus apa saja yang menginfeksi orangutan tersebut. Sampel pada penelitian ini menggunakan sampel feses yang didapat dari 1 individu orangutan sumatera dan 2 individu orangutan kalimantan. Sampel diambil tiga kali dalam kurun waktu yang berbeda dengan interval 3 minggu. Sampel feses diambil pada pagi hari kemudian ditambahkan dengan formalin 10% dengan perbandingan 1:1. Pemeriksaan sampel dengan menggunakan metode floatasi, metode modified Ziehl-Neelsen, dan metode sedimentasi formol-eter. Hasil dari penelitian ini menunjukkan bahwa 2 dari 3 orangutan di Taman Satwa Sumatera Utara positif terinfeksi protozoa gastrointestinal. Orangutan sumatera bernama Stevee tidak terifeksi protozoa gastrointestinal dan orangutan kalimantan bernama Simba dan Hamidah positif terinfeksi genus protozoa gastrointestinal yaitu, Entamoeba sp., Balantidium sp. dan Cryptosporidium parvum.
Valiasi Metode Analisis Penetapan Kadar Linkomisin pada Ayam Broiler menggunakan Kromatografi Cair Kinerja Tinggi (KCKT)
Authors: Muzaki Alfian Yusak , Wibisono Cahyo , Irianti Ika Nindya , Wijayanti Agustina Dwi , Widiasih Dyah Ayu
Published: September 2023

Antibiotik adalah obat yang sering digunakan dalam pengobatan infeksi bakteri dengan menghambat pertumbuhan atau dengan membunuh bakteri. Salah satu obat yang sering digunakan untuk terapi bakteri pada ayam broiler adalah lincomycin, yaitu antibiotik bubuk larut yang digunakan untuk mengobati penyakit menular seperti penyakit pernapasan kronis kompleks (CRD) dan mikoplasmosis. Penggunaan antibiotik pada ayam broiler meningkatkan risiko residu karena kadar obat yang tertinggal, sehingga perlu dilakukan metode analisis kadar lincomycin menggunakan High Performance Liquid Chromatography (HPLC). Penelitian ini bertujuan untuk mengetahui validitas metode analisis kadar linkomisin pada ayam dengan HPLC merk Shimadzu 6.1, fase gerak yang terdiri dari campuran buffer dan asetonitril (89:11) dengan aliran laju 1 ml/menit, detektor UV Vis dengan panjang gelombang 220 nm, dan kolom C18 Shim-pack berukuran 150 L x 4,6 mm pada 350C. Hasil penelitian menunjukkan bahwa nilai-nilai tersebut sesuai dengan kriteria validasi berdasarkan linearitas, spesifisitas, akurasi, presisi, parameter Limit of Detection (LOD), dan Limit of Quantification (LOQ) atau batas kuantifikasi. Kesimpulan yang diperoleh adalah metode analisis kadar lincomycin menggunakan HPLC ini memiliki kriteria yang sesuai dan dapat digunakan untuk mengukur kadar lincomycin pada ayam broiler.
Profil Hematologi Tikus Putih (Rattus norvegicus) yang Diberi Salep Simplisia Daun Kembang Sepatu (Hibiscus rosa-sinensis L.) Setelah Dipapar Sinar Ultraviolet
Authors: Brahmananda Wayan Gede Ananta , Sudisma I Gusti Ngurah , Kendran Anak Agung Sagung , Sudira I Wayan
Published: September 2023

Sinar ultraviolet (UV) dapat merusak kulit dan mempengaruhi darah sehingga dibutuhkan antioksidan yang terkandung dalam daun kembang sepatu. Tujuan penelitian ini untuk mengetahui pengaruh antioksidan pada salep simplisia daun kembang sepatu (Hibiscus rosa-sinensis L.) terhadap profil hematologi tikus putih (Rattus norvegicus) setelah paparan UV. Rancangan penelitian menggunakan metode rancangan acak lengkap (RAL) dengan sampel 30 ekor tikus putih galur wistar berjenis kelamin betina (100-150 gram) dibagi menjadi 6 perlakuan yang setiap kelompok terdiri dari 5 ekor tikus, yaitu (P0) sampel kontrol negatif tanpa diberi salep dan paparan UV, (P1) sampel kontrol positif tanpa diberi salep dan hanya dipapar UV, dan (P2, P3, P4, dan P5) sampel dengan pemberian salep simplisia daun kembang sepatu masing-masing dengan konsentrasi 10%, 20%, 30%, dan 40% secara topikal pada punggung yang sudah dicukur terlebih dahulu seluas 16 cm2 , kemudian dipapar UV. Spesimen darah diambil satu hari setelah perlakuan melalui vena orbitalis, selanjutnya dilakukan uji hematologi lengkap untuk mengetahui jumlah eritrosit (RBC), nilai hematokrit (HCT), kadar hemoglobin (Hb), dan jumlah leukosit (WBC). Hasil penelitian menunjukkan bahwa pemberian salep simplisia daun kembang sepatu dapat mempertahankan jumlah RBC, nilai HCT, kadar Hb, dan jumlah WBC pada tikus kelompok perlakuan (P2, P3, P4, dan P5) dengan konsentrasi simplisia daun kembang sepatu (10%, 20%, 30%, dan 40%) menunjukkan hasil yang tidak berbeda signifikan (P>0,05) terhadap tikus perlakuan kontrol negatif (P0). Dari hasil penelitian ini dapat disimpulkan, pemberian salep simplisia daun kembang sepatu pada tikus putih setelah dipapar UV dapat mempertahankan jumlah RBC, nilai HCT, kadar Hb, dan jumlah WBC.
Resistansi Penisilin terhadap Escherichia coli pada Susu Segar yang berasal dari Koperasi Ternak Sapi Cianjur Utara (KPSCU), Jawa Barat
Authors: Suherman Dwida Agustina , Sudarnika Etih , Purnawarman Trioso
Published: September 2023

Resistansi antibiotik atau sering disebut sebagai pandemi senyap, merupakan satu diantara penyebab masalah kesehatan global yang harus diwaspadai. Susu segar merupakan media pembawa yang mudah terkontaminasi bakteri, salah satunya ialah bakteri E. coli. Antibiotik yang sering dipakai dalam pengobatan terhadap sapi adalah penisilin yaitu antibiotik golongan betalatam yang memiliki kemampuan membunuh bakteri dengan mencegah pembentukan protein dinding sel. Tujuan penelitian ini adalah untuk mendeteksi keberadaan dan prevalensi E. coli pada susu segar, serta menguji resistansinya terhadap antibiotik penisilin. Sebanyak 75 sampel susu kandang dipilih secara acak, berasal dari 6 kelompok ternak sapi perah dan dikumpulkan oleh masing-masing petugas lapang. Uji identifikasi keberadaan E. coli mengacu kepada Standar Nasional Indonesia (SNI) nomor 01-2897-2008 tentang metode pengujian cemaran mikroba pada susu, daging dan telur. Isolat bakteri yang teridentfikasi E. coli dilaukan pengujian resistansi terhadap antibiotik penisilin menggunakan metode Kirby-Bauer disk diffusion dengan penentuan standar berdasarkan Clinical and Laboratory Standards Institute (CLSI). Wawancara terstruktur dilakukan kepada 75 peternak yang diambil sampel susu kandang. Data yang diperoleh dianalisis secara deskriptif. Hasil identifikasi menunjukkan bahwa bakteri E. coli yang terdeteksi pada sampel susu kandang sebanyak 24/75 isolat (32%). Hasil uji resistansi menunjukkan bahwa sebanyak 23/24 isolat E. coli (96%) resistan terhadap antibiotik penisilin. Kesimpulan dari penelitian ini E. coli yang berhasil diisolasi dari susu kandang di wilayah KPSCU telah resistan terhadap antibiotik penisilin, sehingga dibutuhkan penerapan praktik higiene sanitasi, pengawasan penggunaan antibiotik, peningkatan pengetahuan peternak dan petugas kesehatan hewan terkait penggunaan antibiotik di lapangan.
MAPPING AGRICULTURAL WASTE FOR BIOGAS PRODUCTION USING A FULLY CONVOLUTIONAL NEURAL NETWORK AND REMOTE SENSING IMAGERY
Authors: Milošević Maša , Petrović Emina , Momčilović Ana , Stefanović Gordana , Simonović Miloš
Published: September 2023

The increasing generation of waste and depletion of natural resources has led to a growing need for innovative approaches for utilizing different types of waste as potential energy and material resources. Agricultural activities produce large amounts of Agricultural Waste (AW), which, if not adequately managed, can lead to environmental degradation. One potential solution for the effective utilization of AW is converting it into biogas. However, commercializing this process requires a comprehensive understanding of the types and quantities of AW generated. In this paper, the use of a Fully Convolutional Neural Network (FCN), which has rapidly advanced with the progress of Artificial Intelligence and become essential for tasks such as Semantic Segmentation, Object Detection, and Image Classification, is proposed to improve the prediction of AW for biogas production. Furthermore, this paper presents a Deep Learning-based image segmentation method to recognize vineyard fields, which are a significant source of AW, using remote satellite images. The proposed approach can significantly improve the identification of AW sources, and thus contribute to the efficient and sustainable utilization of AW for biogas production.