bluuebunny/crossref_metadata_2025 huggingface dataset:
The Microbial Degradation of Natural and Anthropogenic Phosphonates
Authors: Ruffolo Francesca , Dinhof Tamara , Murray Leanne , Zangelmi Erika , Chin Jason P. , Pallitsch Katharina , Peracchi Alessio
Published: September 2023

Phosphonates are compounds containing a direct carbon–phosphorus (C–P) bond, which is particularly resistant to chemical and enzymatic degradation. They are environmentally ubiquitous: some of them are produced by microorganisms and invertebrates, whereas others derive from anthropogenic activities. Because of their chemical stability and potential toxicity, man-made phosphonates pose pollution problems, and many studies have tried to identify biocompatible systems for their elimination. On the other hand, phosphonates are a resource for microorganisms living in environments where the availability of phosphate is limited; thus, bacteria in particular have evolved systems to uptake and catabolize phosphonates. Such systems can be either selective for a narrow subset of compounds or show a broader specificity. The role, distribution, and evolution of microbial genes and enzymes dedicated to phosphonate degradation, as well as their regulation, have been the subjects of substantial studies. At least three enzyme systems have been identified so far, schematically distinguished based on the mechanism by which the C–P bond is ultimately cleaved—i.e., through either a hydrolytic, radical, or oxidative reaction. This review summarizes our current understanding of the molecular systems and pathways that serve to catabolize phosphonates, as well as the regulatory mechanisms that govern their activity.
Measurement of Urinary Gc-Globulin by a Fluorescence ELISA Technique: Method Validation and Clinical Evaluation in Septic Patients—A Pilot Study
Authors: Kőszegi Tamás , Horváth-Szalai Zoltán , Ragán Dániel , Kósa Brigitta , Szirmay Balázs , Kurdi Csilla , Kovács Gábor L. , Mühl Diána
Published: September 2023

A major complication of sepsis is the development of acute kidney injury (AKI). In case of acute tubular damage, Gc-globulin, a known serum sepsis marker is increasingly filtrated into the urine therefore, urinary Gc-globulin (u-Gc) levels may predict septic AKI. We developed and validated a competitive fluorescence ELISA method for u-Gc measurement. Serum and urine samples from septic patients were collected in three consecutive days (T1, T2, T3) and data were compared to controls. Intra- and interassay imprecisions were CV < 14% and CV < 20%, respectively, with a recovery close to 100%. Controls and septic patients differed (p < 0.001) in their u-Gc/u-creatinine levels at admission (T1, median: 0.51 vs. 79.1 µg/mmol), T2 (median: 0.51 vs. 57.8 µg/mmol) and T3 (median: 0.51 vs. 55.6 µg/mmol). Septic patients with AKI expressed higher u-Gc/u-creatinine values than those without AKI at T1 (median: 23.6 vs. 136.5 µg/mmol, p < 0.01) and T3 (median: 34.4 vs. 75.8 µg/mmol, p < 0.05). AKI-2 stage patients exhibited more increased u-Gc/u-creatinine levels at T1 (median: 207.1 vs. 53.3 µg/mmol, p < 0.05) than AKI-1 stage individuals. Moderate correlations (p < 0.001) were observed between u-Gc/u-creatinine and se-urea, se-creatinine, se-hsCRP, WBC, u-total protein, u-albumin, u-orosomucoid/u-creatinine, and u-Cystatin C/u-creatinine levels. U-Gc testing may have a predictive value for AKI in septic patients.
Analysis of Volatile Components in Dried Fruits and Branch Exudates of Schisandra chinensis with Different Fruit Colors Using GC-IMS Technology
Authors: Yan Yiping , Lu Wenpeng , Tian Taiping , Shu Nan , Yang Yiming , Fan Shutian , Han Xianyan , Ge Yunhua , Xu Peilei
Published: September 2023

To investigate the volatile components of Schisandra chinensis (Turcz.) Bail (commonly known as northern Schisandra) of different colors and to explore their similarities and differences, to identify the main flavor substances in the volatile components of the branch exudates of northern schisandra, and finally to establish a fingerprint map of the volatile components of the dried fruits and branch exudates of northern Schisandra of different colors, we used GC-IMS technology to analyze the volatile components of the dried fruits and branch exudates of three different colors of northern Schisandra and established a fingerprint spectra. The results showed that a total of 60 different volatile chemical components were identified in the branch exudates and dried fruits of Schisandra. The components of germplasm resources with different fruit colors were significantly different. The ion mobility spectrum and OPLS-DA results showed that white and yellow fruits were more similar compared to red fruits. The volatile components in dried fruits were significantly higher than those in branch exudates. After VIP (variable importance in projection) screening, 41 key volatile substances in dried fruits and 30 key volatile substances in branch exudates were obtained. After screening by odor activity value (OAV), there were 24 volatile components greater than 1 in both dried fruits and branch exudates. The most important contributing volatile substance was 3-methyl-butanal, and the most important contributing volatile substance in white fruit was (E)-2-hexenal.
Electron Transport Properties of Graphene/WS2 Van Der Waals Heterojunctions
Authors: Guo Junnan , Dai Xinyue , Zhang Lishu , Li Hui
Published: September 2023

Van der Waals heterojunctions of two-dimensional atomic crystals are widely used to build functional devices due to their excellent optoelectronic properties, which are attracting more and more attention, and various methods have been developed to study their structure and properties. Here, density functional theory combined with the nonequilibrium Green’s function technique has been used to calculate the transport properties of graphene/WS2 heterojunctions. It is observed that the formation of heterojunctions does not lead to the opening of the Dirac point of graphene. Instead, the respective band structures of both graphene and WS2 are preserved. Therefore, the heterojunction follows a unique Ohm’s law at low bias voltages, despite the presence of a certain rotation angle between the two surfaces within the heterojunction. The transmission spectra, the density of states, and the transmission eigenstate are used to investigate the origin and mechanism of unique linear I–V characteristics. This study provides a theoretical framework for designing mixed-dimensional heterojunction nanoelectronic devices.
An Unprecedented CeO2/C Non-Noble Metal Electrocatalyst for Direct Ascorbic Acid Fuel Cells
Authors: Qiu Chenxi , Zhou Qiang , Gao Rui , Guo Yizheng , Qin Jiaqi , Wang Dongqi , Song Yujiang
Published: September 2023

Direct ascorbic acid fuel cells (DAAFCs) employ biocompatible ascorbic acid (AA) as fuel, allowing convenient storage, transportation, and fueling as well as avoiding fuel crossover. The AA oxidation reaction (AAOR) largely governs the performance of DAAFCs. However, AAOR electrocatalysts currently have low activity, and state-of-the-art ones are limited to carbon black. Herein, we report the synthesis of an unprecedented AAOR electrocatalyst comprising 3.9 ± 1.1 nm CeO2 nanoparticles evenly distributed on carbon black simply by the wet chemical precipitation of Ce(OH)3 and a subsequent heat treatment. The resultant CeO2/C shows a remarkable AAOR activity with a peak current density of 13.1 mA cm−2, which is 1.7 times of that of carbon black (7.67 mA cm−2). According to X-ray photoelectron spectroscopy (XPS), the surface Ce3+ of CeO2 appears to contribute to the AAOR activity. Furthermore, our density functional theory (DFT) calculation reveals that that the proton of the hydroxyl group of AA can easily migrate to the bridging O sites of CeO2, resulting in a faster AAOR with respect to the pristine carbon, -COOH, and -C=O sites of carbon. After an i-t test, CeO2/C loses 17.8% of its initial current density, which is much superior to that of carbon black. CeO2 can capture the electrons generated by the AAOR to protect the -COOH and -C=O sites from being reduced. Finally, DAAFCs fabricated with CeO2/C exhibit a remarkable power density of 41.3 mW cm−2, which is the highest among proton-exchange-membrane-based DAAFCs in the literature.
Resurgence and Repurposing of Antifungal Azoles by Transition Metal Coordination for Drug Discovery
Authors: Cortat Youri , Zobi Fabio
Published: September 2023

Coordination compounds featuring one or more antifungal azole (AA) ligands constitute an interesting family of candidate molecules, given their medicinal polyvalence and the viability of drug complexation as a strategy to improve and repurpose available medications. This review reports the work performed in the field of coordination derivatives of AAs synthesized for medical purposes by discussing the corresponding publications and emphasizing the most promising compounds discovered so far. The resulting overview highlights the efficiency of AAs and their metallic species, as well as the potential still lying in this research area.
Influence of High-Order Twisting Phases on Polarization States and Optical Angular Momentum of a Vector Light Field
Authors: Liu Baoyin , Huang Yingqi , Liu Caixia , Wu Shu-Dan , Chew Khian-Hooi , Chen Rui-Pin
Published: September 2023

This study investigates the influence of high-order twisting phases on polarization states and optical angular momentum of a vector light field with locally linear polarization and a hybrid state of polarization (SoP). The twisted vector optical field (TVOF) is experimentally generated based on the orthogonal polarization bases with high-order twisting phases. The initial SoP of a TVOF modulated by the high-order twisting phase possesses various symmetric distributions. The propagation properties of a high-order TVOF with locally linear polarization and hybrid SoP are explored, including the intensity compression, expansion, and conversion between the linear and circular polarization components. In particular, orbital angular momentum (OAM) appears in a high-order TVOF during propagation where no OAM exists in the initial field. The variation of OAM distribution in cross-section becomes more frequent with the increase of the twisting phase order. In addition, a non-symmetric OAM distribution appears in a non-isotropic TVOF, leading to the rotation of the beam around the propagation axis during propagation. The optical energy flow distribution of a high-order TVOF provides a more profound understanding of the propagation dynamics of high-order TVOF. These results provide a new approach for optical field manipulation in a high-order TVOF.
Research on the Detection Method of Projection Stellar Target Simulator
Authors: Kang Jianan , Zheng Ru , Wang Lingyun , Pang Chengwei , Li Guangxi
Published: September 2023

The projection stellar target simulator is a stellar target simulator in which star points are projected to be imaged on a fixed plane at a fixed distance. Compared with conventional stellar target simulators, the projection stellar target simulator makes star points visible and provides the necessary condition for a semi-physical simulation test of the star camera. In this paper, the projection stellar target simulator optical system with high-quality imaging is designed by combining the projection technology, which breaks the collimated imaging of the conventional stellar target simulator optical system, and offers a new thought to solve the problem of decreasing the calibration accuracy caused by the influence of the coaxiality and other factors in the stellar target simulator calibrating the star camera. Based on the imaging behavior of the star map, this paper proposes a method to realize the automatic detection of a projection stellar target simulator by using CCD and introduces the composition and working principle of the detection system in detail. According to the imaging characteristics of star points, denoising and threshold segmentation of the star map are carried out, and an improved centroid algorithm is proposed to achieve high-precision positioning of the centroid coordinates of the star points. The measurement model and measuring formulas for the angular distance between stars are established. The error sources of the detection system are analyzed and obtain the theoretical error of 9.22″ for this detection system. The result of an actual test experiment shows that the position error of single star is less than 11″, in line with the theoretical analysis of the error, indicating the detection system has high detection precision and meets the requirement for the detection accuracy of the projection stellar target simulator.
Arbuscular Mycorrhizal Fungi Restored the Saline–Alkali Soil and Promoted the Growth of Peanut Roots
Authors: Ci Dunwei , Qin Feifei , Tang Zhaohui , Zhang Guanchu , Zhang Jialei , Si Tong , Yang Jishun , Xu Yang , Yu Tianyi , Xu Manlin , He Kang
Published: September 2023

Peanut (Arachis hypogaea L.) is an important oil and cash crop. An efficient utilization of saline–alkali soil resources, the development of peanut planting in saline–alkali soil, and obtaining high and stable yield have become urgent needs to ensure peanut production. Arbuscular mycorrhizal fungi (AMF) have been reported to develop the potential productivity of host plants and improve their salt resistance and tolerance. However, there is still limited research on promoting the growth and morphology of peanut roots. Therefore, in this study, seeds of salt-tolerant peanut variety “HY 25” were coated with commercial AMF inoculant before being planted in saline–alkali and normal soils to investigate the effects of AMF on peanut root growth and rhizosphere soil. The results showed that root morphological characteristics were significantly increased by the use of AMF at the podding stage in saline–alkali soil and from the flowering and pegging stage to the maturity stage in normal soil. Of note, the total root volume of peanut inoculated with AMF significantly increased by 31.57% during the podding stage in saline–alkali soil. Meanwhile, AMF significantly increased the phosphatase and invertase activities in the peanut rhizosphere of saline–alkali soil from the flowering stage to maturity stage and soil CAT activity at the maturity stage (41.16~48.82%). In normal soil, soil phosphatase and urease activities were enhanced by AMF at the flowering stage and the podding stage, respectively. AMF also increased the contents of soil organic matter, available phosphorus, and hydrolysable nitrogen, but decreased soil EC in saline–alkali soil. In addition to the significant increase in soil available phosphorus content, AMF had no significant effect on the physical and chemical properties of the soil and other soil nutrients in normal soil. AMF significantly increased pod biomass and yield in saline–alkali soil and normal soil, and improved their agronomic characteristics. In conclusion, peanut seeds coated with AMF improved the root morphological characteristics of peanuts and improved the physical and chemical properties in peanut rhizosphere, especially in saline–alkali soil. The process of rhizosphere soil nutrient transformation was also enhanced. Finally, AMF improved plant agronomic traits to increase the pod yield (16.5~21.9%). This study provides the theoretical basis and technical support for the application of AMF in peanut production in saline–alkali soil.
Characteristics and Pathogenicity of Discula theae-sinensis Isolated from Tea Plant (Camellia sinensis) and Interaction with Colletotrichum spp.
Authors: Li Qingsheng , Zhu Junyan , Ren Ning , Li Da , Jin Ya , Lu Wenyuan , Lu Qinhua
Published: September 2023

Anthracnose is one of the primary diseases in tea plants that affect tea yield and quality. The geographical distribution, occurrence regularity, and agronomic measures of tea plants with anthracnose have been researched for decades. However, the pathogenic cause of anthracnose in tea plants is diverse in different regions of the world. Identifying the specific pathogenic fungi causing tea anthracnose is an essential control measure to mitigate this disease. In this study, 66 Discula theae-sinensis and 45 Colletotrichum isolates were obtained from three different types of diseased tea leaves. Based on multilocus phylogenetic and morphological analysis, eight known species of Colletotrichum, Colletotrichum fructicola, C. camelliae, C. aenigma, C. siamense, C. henanense, C. karstii, C. tropicicola, and C. gigasporum were identified. This study is the first to report C. tropicicola and C. gigasporum in tea plants in China. Discula theae-sinensis was the most common species in this study and caused disease lesions around wounded areas of tea leaves. The dual trials in vitro indicated Discula theae-sinensis and Colletotrichum were slightly inhibited. Co-inoculating Discula theae-sinensis and C. fructicola was superior to single inoculation at low concentrations. The main cause of anthracnose might be the concerted action of a variety of fungi.
Enhancing Sugarcane Yield and Sugar Quality through Optimal Application of Polymer-Coated Single Super Phosphate and Irrigation Management
Authors: Sajid Muhammad , Amjid Muhammad , Munir Hassan , Valipour Mohammad , Rasul Fahd , Khil Aka , Alqahtani Mashael Daghash , Ahmad Muhammad , Zulfiqar Usman , Iqbal Rashid , Ali Muhammad Fraz , Ibtahaj Iqra
Published: September 2023

The judicious use of crop input is of prime importance for achieving a considerable output with a low-cost input. A two-year field experimentation was executed to assess the effect of varying polymer-coated single super phosphate (SSP) regimes on the yield and quality of sugarcane under differential water regimes. A two-factor study was executed under a randomized complete block design with a split-plot arrangement. The CPF-249 sugarcane variety was planted during the 2019–2020 period and the 2020–2021 period. The experiment consisted of four levels of polymer-coated SSP, i.e., control, 90, 110, and 130 kg ha−1, and three water regimes, which consisted of a number of irrigations, i.e., 18 irrigations, 15 irrigations, and 12 irrigations. Moreover, the water regimes were kept in the main plot, whereas the polymer-coated supplement was allocated in a subplot and replicated thrice. The data on the yield components and sugar-related traits were recorded during both years of study, and the treatment means were differentiated using an LSD test at a 95% confidence interval. Summating the findings of this study, a significant variation was revealed under the subject levels of both factors. Statistically, a 110 kg ha−1 polymer-coated SSP dose, along with 18 irrigations, declared the highest millable canes, stripped cane yield, and unstripped cane yield, followed by the 130 kg ha−1 treatment. Additionally, the highest pol% and cane sugar recovery % were recorded under 12 irrigations along with 130 kg ha−1 during both years. Similarly, the °Brix value was also significantly affected by 12 irrigations when 110 kg ha−1 of polymer-coated SSP was used. The unstripped cane yield had a strong positive correlation with the stripped cane yield, millable canes, and the number of internodes. Moreover, the commercial cane sugar % resulted in a strong positive correlation with the pol%, whereas the cane sugar recovery % revealed a strong positive correlation with the pol% and commercial cane sugar %.
Effect of Eco-Friendly Application of Bee Honey Solution on Yield, Physio-Chemical, Antioxidants, and Enzyme Gene Expressions in Excessive Nitrogen-Stressed Common Bean (Phaseolus vulgaris L.) Plants
Authors: Belal Hussein E. E. , Abdelpary Mostafa A. M. , Desoky El-Sayed M. , Ali Esmat F. , Al Kashgry Najla Amin T. , Rady Mostafa M. , Semida Wael M. , Mahmoud Amr E. M. , Sayed Ali A. S.
Published: September 2023

Excessive use of nitrogen (N) pollutes the environment and causes greenhouse gas emissions; however, the application of eco-friendly plant biostimulators (BSs) can overcome these issues. Therefore, this paper aimed to explore the role of diluted bee honey solution (DHS) in attenuating the adverse impacts of N toxicity on Phaseolus vulgaris growth, yield quality, physio-chemical properties, and defense systems. For this purpose, the soil was fertilized with 100, 125, and 150% of the recommended N dose (RND), and the plants were sprayed with 1.5% DHS. Trials were arranged in a two-factor split-plot design (N levels occupied main plots × DH– occupied subplots). Excess N (150% RND) caused a significant decline in plant growth, yield quality, photosynthesis, and antioxidants, while significantly increasing oxidants and oxidative damage [hydrogen peroxide (H2O2), superoxide (O2•−), nitrate, electrolyte leakage (EL), and malondialdehyde (MDA) levels]. However, DHS significantly improved antioxidant activities (glutathione and nitrate reductases, catalase, ascorbate peroxidase, superoxide dismutase, proline, ascorbate, α-tocopherol, and glutathione) and osmoregulatory levels (soluble protein, glycine betaine, and soluble sugars). Enzyme gene expressions showed the same trend as enzyme activities. Additionally, H2O2, O2•−, EL, MDA, and nitrate levels were significantly declined, reflecting enhanced growth, yield, fruit quality, and photosynthetic efficiency. The results demonstrate that DHS can be used as an eco-friendly approach to overcome the harmful impacts of N toxicity on P. vulgaris plants.
Genetic and Morpho-Physiological Differences among Transgenic and No-Transgenic Cotton Cultivars
Authors: Liu Li , Wang Dan , Hua Jinping , Kong Xianhui , Wang Xuwen , Wang Juan , Si Aijun , Zhao Fuxiang , Liu Wenhao , Yu Yu , Chen Zhiwen
Published: September 2023

Three carbon-chain extension genes associated with fatty acid synthesis in upland cotton (Gossypium hirsutum), namely GhKAR, GhHAD, and GhENR, play important roles in oil accumulation in cotton seeds. In the present study, these three genes were cloned and characterized. The expression patterns of GhKAR, GhHAD, and GhENR in the high seed oil content cultivars 10H1014 and 10H1041 differed somewhat compared with those of 10H1007 and 2074B with low seed oil content at different stages of seed development. GhKAR showed all three cultivars showed higher transcript levels than that of 2074B at 10-, 40-, and 45-days post anthesis (DPA). The expression pattern of GhHAD showed a lower transcript level than that of 2074B at both 10 and 30 DPA but a higher transcript level than that of 2074B at 40 DPA. GhENR showed a lower transcript level than that of 2074B at both 15 and 30 DPA. The highest transcript levels of GhKAR and GhENR were detected at 15 DPA in 10H1007, 10H1014, and 10H1041 compared with 2074B. From 5 to 45 DPA cotton seed, the oil content accumulated continuously in the developing seed. Oil accumulation reached a peak between 40 DPA and 45 DPA and slightly decreased in mature seed. In addition, GhKAR and GhENR showed different expression patterns in fiber and ovule development processes, in which they showed high expression levels at 20 DPA during the fiber elongation stage, but their expression level peaked at 15 DPA during ovule development processes. These two genes showed the lowest expression levels at the late seed maturation stage, while GhHAD showed a peak of 10 DPA in fiber development. Compared to 2074B, the oil contents of GhKAR and GhENR overexpression lines increased 1.05~1.08 folds. These results indicated that GhHAD, GhENR, and GhKAR were involved in both seed oil synthesis and fiber elongation with dual biological functions in cotton.
Modeling the Impact of Agricultural Mitigation Measures on the Spread of Sharka Disease in Sweet Cherry Orchards
Authors: Gutiérrez-Jara Juan Pablo , Vogt-Geisse Katia , Correa Margarita C. G. , Vilches-Ponce Karina , Pérez Laura M. , Chowell Gerardo
Published: September 2023

Sharka is a disease affecting stone fruit trees. It is caused by the Plum pox virus (PPV), with Myzus persicae being one of the most efficient aphid species in transmitting it within and among Prunus orchards. Other agricultural management strategies are also responsible for the spread of disease among trees, such as grafting and pruning. We present a mathematical model of impulsive differential equations to represent the dynamics of Sharka disease in the tree and vector population. We consider three transmission routes: grafting, pruning, and through aphid vectors. Grafting, pruning, and vector control occur as pulses at specific instants. Within the model, human risk perception towards disease influences these agricultural management strategies. Model results show that grafting with infected biological material has a significant impact on the spread of the disease. In addition, detecting infectious symptomatic and asymptomatic trees in the short term is critical to reduce disease spread. Furthermore, vector control to prevent aphid movement between trees is crucial for disease mitigation, as well as implementing awareness campaigns for Sharka disease in agricultural communities that provide a long-term impact on responsible pruning, grafting, and vector control.
A Coherent Assessment of the Compressive Strain Rate Response of PC, PETG, PMMA, and TPU Thermoplastics in MEX Additive Manufacturing
Authors: Petousis Markos , Ntintakis Ioannis , David Constantine , Sagris Dimitrios , Nasikas Nektarios K. , Korlos Apostolos , Moutsopoulou Amalia , Vidakis Nectarios
Published: September 2023

In this study, we successfully address a significant research and engineering gap by quantitatively assessing the impact of varying compressive loading rates on the mechanical behavior of four popular thermoplastic polymers in material-extrusion-based (MEX) 3D printing. Raw powders of polycarbonate (PC), polyethylene terephthalate glycol (PETG), polymethyl methacrylate (PMMA), and thermoplastic polyurethane (TPU) were processed through melt extrusion, and the filaments were used to 3D-print the test samples. For completeness, thermogravimetric analysis and a compressive test following the ASTM-D695 standard were conducted. Ultimately, the compressive strength and yield stress, the compressive modulus of elasticity and toughness, and the maximum compressive sensitivity index were thoroughly documented. Specimens were tested in strain rates from 1.3 mm/min to 200 mm/min. The compressive strength (40% for the PMMA) and stiffness (29% for the TPU) increased with the increase in the strain rate in all polymers tested. PC had the highest strain rate sensitivity. Significant variations in deformation and fracture modes were observed and thoroughly documented throughout this study. Our findings can be useful in industrial engineering as valued design optimization input parameters in various applications involving the above-mentioned polymeric materials.
Mevacor/Poly(vinyl acetate/2-hydroxyethyl methacrylate) as Solid Solution: Preparation, Solubility Enhancement and Drug Delivery
Authors: Alassaf Mohammed , Alqahtani Saad Mohammed , Al Khulaifi Rana Salem , Saeed Waseem Sharaf , Alsubaie Faisal S. , Semlali Abdelhabib , Aouak Taieb
Published: September 2023

Mevacor/Poly(vinyl acetate-co-2-hydroxyethyl methacrylate) drug carrier systems (MVR/VAC-HEMA) containing different Mevacor (MVR) contents were prepared in one pot by free radical copolymerization of vinyl acetate with 2-hydroxyethyl methacrylate using an LED lamp light in the presence of camphorquinone as a photoinitiator and Mevacor as a drug filler. The prepared material was characterized by FTIR, 1H NMR, DSC, SEM and XRD methods. Different parameters influencing the efficiency in the Mecvacor-water solubility and the drug delivery of this system, such as the swelling capacity of the carrier, the amount of Mevacor loaded and the pH medium have been widely investigated. The results obtained revealed that the Mevacor particles were uniformly dispersed in their molecular state in the copolymer matrix forming a solid solution; the cell toxicity of the virgin poly(vinyl acetate-co-2-hydroxy ethyl methacrylate) (VAC-HEMA) and MVR/VAC-HEMA drug carrier system exhibited no significant effect on their viability when between 0.25 and 2.00 wt% was loaded in these materials; the average swelling capacity of VAC-HEMA material in water was found to be 45.16 wt%, which was practically unaffected by the pH medium and the solubility of MVR deduced from the release process reached more than 22 and 37 times that of the powder dissolved directly in pH 1 and 7 media, respectively. The in vitro MVR release kinetic study revealed that the MVR/VAC-HEMA system containing 0.5 wt% MVR exhibited the best performance in the short gastrointestinal transit (GITT), while that containing 2.0 wt% is for the long transit as they were able to considerably reduce the minimum release of this drug in the stomach (pH1).
Effect of Different Ratios of Gasoline-Ethanol Blend Fuels on Combustion Enhancement and Emission Reduction in Electronic Fuel Injection Engine
Authors: Ye Yanshuai , Hu Jingyi , Zhang Zhiqing , Zhong Weihuang , Zhao Ziheng , Zhang Jian
Published: September 2023

The severity of engine emissions for the environment and human health cannot be ignored. This article optimizes the combustion and emission of gasoline-cassava bioethanol fuel blends in electronic fuel injection engines using response surface methodology to achieve the goal of reducing carbon and pollutant emissions. The experiment investigated the effects of different gasoline-cassava bioethanol mixing ratios (G100, G90E10, G80E20, and G70E30) on engine performance, including torque, brake specific fuel consumption, power, total hydrocarbons, nitrogen oxides, and carbon monoxide emissions. The results show that the gasoline-cassava bioethanol fuel blend is not as good as G100 in terms of braking power, torque, and brake specific fuel consumption, but better than G100 in terms of carbon monoxide emissions and total hydrocarbon emissions. Then, the optimization objective function was determined, and the combustion and emission characteristics were optimized using the response surface methodology method. The optimization results indicate that the response surface methodology method can determine the interaction between design variables such as brake specific fuel consumption, nitrogen oxides, and total hydrocarbon emissions and find the best solution. In this experiment, the independent variables of the best solution were 72.9 N·m torque, 30% G70E30 mixing rate, and 2000 rpm speed, corresponding to brake specific fuel consumption at 313 g/(kW·h), nitrogen oxide emissions at 2.85 × 103 ppm, and total hydrocarbon emissions at 166 ppm. The findings of this study indicate that by optimizing the gasoline-cassava bioethanol mixture ratio, lower emission levels can be achieved in electronic fuel injection engines, thereby promoting the sustainable development of renewable energy and reducing pollutant emissions.
Thermal Degradation Studies of Poly(2-ethyl hexyl acrylate) in the Presence of Nematic Liquid Crystals
Authors: Bouriche Amina , Alachaher-Bedjaoui Lamia , Barrera Ana , Staelens Jean-Noël , Maschke Ulrich
Published: September 2023

The thermal degradation behavior of Poly(2-ethyl hexyl hcrylate) (Poly(2-EHA)), blended with a commercially available nematic liquid crystal (LC) mixture, was investigated by thermal gravimetric analysis (TGA). Different heating rates, ranging from 5 to 200 °C/min, were applied under an inert atmosphere. Based on the TGA results, activation energies (Eα) at different conversion rates (α) were determined using three integral isoconversion methods: Flynn-Wall-Ozawa (FWO), Tang, and Kissinger-Akahira-Sunose (KAS). It can be noticed that the global evolution of these activation energies was the same for the three models. The coefficient of determination R2 presented values generally higher than 0.97. Using these models, the Eα value for the LC remains constant at 64 kJ/mol for all conversions rates. For the polymer Poly(2-EHA), applying the Tang and FWO models, the activation energy presents a variation ranging from 80 kJ/mol, for conversion α = 0.1, to 170 kJ/mol, for α = 0.9. For the third model (KAS), this energy varies between 80 and 220 kJ/mol in the same range of α.
Advancing Smart Textiles: Structural Evolution of Knitted Piezoresistive Strain Sensors for Enabling Precise Motion Capture
Authors: Warncke Mareen N. , Böhmer Carola H. , Sachse Carmen , Fischer Susanne , Häntzsche Eric , Nocke Andreas , Mersch Johannes , Cherif Chokri
Published: September 2023

Recently, there has been remarkable progress in the development of smart textiles, especially knitted strain sensors, to achieve reliable sensor signals. Stable and reliable electro-mechanical properties of sensors are essential for using textile-based sensors in medical applications. However, the challenges associated with significant hysteresis and low gauge factor (GF) values remain for using strain sensors for motion capture. To evaluate these issues, a comprehensive investigation of the cyclic electro-mechanical properties of weft-knitted strain sensors was conducted in the present study to develop a drift-free elastic strain sensor with a robust sensor signal for motion capture for medical devices. Several variables are considered in the study, including the variation of the basic knit pattern, the incorporation of the electrically conductive yarn, and the size of the strain sensor. The effectiveness and feasibility of the developed knitted strain sensors are demonstrated through an experimental evaluation, by determining the gauge factor, its nonlinearity, hysteresis, and drift. The developed knitted piezoresistive strain sensors have a GF of 2.4, a calculated drift of 50%, 12.5% hysteresis, and 0.3% nonlinearity in parts.
Polymer-Grade Bio-Monomers from Oleochemicals by Combining Homogeneous Catalysis and Selective Product Crystallization in an Integrated Process
Authors: Seifert Astrid Ina , Wegener Hannes Wolfgang , Brühl Katharina , Seidensticker Thomas , Wohlgemuth Kerstin
Published: September 2023

The homogeneously catalyzed methoxycarbonylation of bio-based methyl 10-undecenoate (C11-DME) produces linear 1,12-dimethyl dodecanedioate (l-C12-DME). Subsequent selective product crystallization from the reaction mixture with downstream filtration and washing allows for the generation of the bio-monomer in polymer grade quality (>99.9%). This effective purification enables its direct use, e.g., for bio-based polyamides, without further purification. It separates the expensive homogeneous catalyst dissolved in the liquid phase in its active state for efficient catalyst recycling. We present the complex interactions of process parameters regarding reaction and crystallization-based purification in an integrated catalyst recycling process. Furthermore, we demonstrate that purification of l-C12-DME with >99.9% purity over multiple consecutive recycling runs is possible. However, as the crystallization is highly sensitive towards changing concentrations of by-products and particularly unreacted substrates, this high purity is only achieved by maintaining a stable composition in the reaction mixture using a newly developed system for precise conversion control in the reaction step.
Verifying the Optimal Extraction Method and Content of Red Okra Extracts and Crude Pectin Using Response Surface Methodology (RSM)
Authors: Son Seon ah , Kim Youngbae , Kim Eun , Lee Ki Hoon , Kang Wan Seok , Kim Kyeong Jo , Lim Dosung , Choi Su-young , Kim Jin Seok , Shin Tai-Sun , Kim Sunoh
Published: September 2023

Recently, many studies have reported the properties and functionality of okra pectin. However, these studies are about green okra pods, and pectin in red okra pods, stems, and roots has not been reported. Therefore, this study aimed to optimize the red okra extraction method using response surface methodology (RSM) analysis and evaluate the effects of extraction time, temperature, solvent ratio, and pH on the extract yield and crude pectin content. Based on RSM analysis, 4.35 h, 98.04 °C, 23.34 solvent ratio, and pH 3.36 are the optimal parameters for extracting crude pectin from red okra, and the crude pectin content was predicted to be 40.83%. When red okra was extracted under these extraction conditions (4 h, 100 °C, 23 solvent ratio, and pH 3), the extraction yield was 45.26%, and the crude pectin content was 38.42%, which was similar to the yield obtained under the conditions derived from the RSM analysis. In addition, the pH control using hydrochloric acid was replaced with citric acid, and the changes in extract yield and crude pectin content were compared. When citric acid was used, the extract yield was 49.15% (8.6% increase), and the crude pectin content was 42.76 ± 2.56% (11.3% increase); compared to when hydrochloric acid was used, the yield increased. Finally, the standardization of red okra raw materials was determined by analyzing the extraction yield and crude pectin content by part, harvest time, and size of red okra using the established extraction method using citric acid. As a result, it was confirmed that the extraction yield obtained from the established extraction method was reached from the extraction of red okra fruits up to 12 cm in size that were harvested between July and November. Additionally, compared to the non-pectin fraction, the crude pectin fraction isolated from red okra pod extract showed significantly higher total phenolic content (TPC) and total flavonoid content (TFC). These findings, reported for the first time, may contribute to the development of processes to purify red okra pectin, functional evaluation studies of pectin, and potential applications of red okra extract in various industries and research.
An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing
Authors: Hadad Mohammadjafar , Attarsharghi Samareh , Makarian Javad , Mahdianikhotbesara Ali
Published: September 2023

The significant effect of the dressing process on the surface of the grinding wheel (GW) and the need to provide an optimal dressing condition are the requirements of reduction machining time and energy consumption in the sustainable grinding process. In this study, for the first time, the results of changes in the parameters of the dressing process and changes in the topography of the grinding surface on the surface roughness of the Inconel 738 have been presented using single-edge and four-edge diamond dressers. The use of minimum quantity lubrication (MQL) and wet condition are other variables in this study to reduce the consumption of cutting fluid and prevent its destructive effects on the environment. The results indicate that the MQL technique increases the grinding performance of Inconel 738 by reducing ground workpiece surface roughness and decreasing the coolant–lubricant consumption comparing to the conventional wet grinding process. Additionally, it has been found from the experimental results that applying a single-edge dresser generates finer topography on the grinding wheel and, consequently, has a better surface finish in the grinding process compared to the multipoint diamond dressing tool with the same dressing and grinding parameters. In other words, increasing the dressing feed rate during dressing of the grinding wheel using a multipoint dresser makes a finer wheel surface topography and as a result decreases the surface roughness of the ground workpiece compared to a single-edge dresser. With multipoint diamond tools, the grinding performance during the life of the dressing tool also tends to remain more consistent, which is a definite advantage in automated production. Therefore, application of a multipoint dresser leads to a reduction in dressing time and increased production capability.
Discretionary Extensions to Unemployment Insurance Compensation and Some Potential Costs for a McCall Worker
Authors: Ryan Rich
Published: September 2023

Unemployment insurance provides temporary cash benefits to eligible unemployed workers. Benefits are sometimes extended by discretion during economic slumps. In a model that features temporary benefits and sequential job opportunities, a worker’s reservation wages are studied when policymakers can make discretionary extensions to benefits. A worker’s optimal labor-supply choice is characterized by a sequence of reservation wages that increases with weeks of remaining benefits. The possibility of an extension raises the entire sequence of reservation wages, meaning a worker is more selective when accepting job offers throughout their spell of unemployment. The welfare consequences of misperceiving the probability and length of an extension are investigated. Properties of the model can help policymakers interpret data on reservation wages, which may be important if extended benefits are used more often in response to economic slumps, virus pandemics, extreme heat, and natural disasters.
Three-Dimensional Flight Corridor: An Occupancy Checking Process for Unmanned Aerial Vehicle Motion Planning inside Confined Spaces
Authors: Mostafa Sherif , Ramirez-Serrano Alejandro
Published: September 2023

To deploy Unmanned Aerial Vehicles (UAVs) inside heterogeneous GPS-denied confined (potentially unknown) spaces, such as those encountered in mining and Urban Search and Rescue (USAR), requires the enhancement of numerous technologies. Of special interest is for UAVs to identify collision-freeSafe Flight Corridors (SFC+) within highly cluttered convex- and non-convex-shaped environments, which requires UAVs to perform advanced flight maneuvers while exploiting their flying capabilities. Within this paper, a novel auxiliary occupancy checking process that augments traditional 3D flight corridor generation is proposed. The 3D flight corridor is established as a topological structure based on a hand-crafted path either derived from a computer-generated environment or provided by the human operator, which captures humans’ preferences and desired flight intentions for the given space. This corridor is formulated as a series of interconnected overlapping convex polyhedra bounded by the perceived environmental geometries, which facilitates the generation of suitable 3D flight paths/trajectories that avoid local minima within the corridor boundaries. An occupancy check algorithm is employed to reduce the search space needed to identify 3D obstacle-free spaces in which their constructed polyhedron geometries are replaced with alternate convex polyhedra. To assess the feasibility and efficiency of the proposed SFC+ methodology, a comparative study is conducted against the Star-Convex Method (SCM), a prominent algorithm in the field. The results reveal the superiority of the proposed SFC+ methodology in terms of its computational efficiency and reduced search space for UAV maneuvering solutions. Various challenging confined-environment scenarios, each with different obstacle densities (confined scenarios), are utilized to verify the obtained outcomes.
Evaluation of Coupling Coordination Degree between Economy and Eco-Environment Systems in the Yangtze River Delta from 2000 to 2020
Authors: Ji Jianwan , Wang Litao , Xie Maorong , Lv Wen , Yu Cheng , Liu Wenliang , Shifaw Eshetu
Published: September 2023

The quantitative evaluation of the coupling coordination degree (CCD) between the regional economy and eco-environment systems is of great importance for the realization of sustainable development goals, which could identify economic or eco-environmental cold areas. To date, traditional evaluation frameworks mainly include the indicator system construction based on statistical data, which seldom utilize the geo-spatiotemporal datasets. Hence, this study aimed to evaluate the CCD change trend of the Yangtze River Delta (YRD) and explore the relationship between the CCD, economy, and eco-environment on the county scale. In this study, YRD was selected as the study area to evaluate its level of CCD at different periods, and then the nighttime difference index (NTDI) and eco-environmental comprehensive evaluation index (ECEI) were calculated to represent the difference in the development of the regional economy and the eco-environmental quality (EEQ). The CCD between the two systems was then calculated and analyzed using global, local, and Geary’s C spatial autocorrelation indicators, in addition to change trend methods. The main findings showed that: (1) During the period 2000–2020, the economic system in YRD showed a continuously upward trend (0.0487 a−1), with average NTDI values of 0.2308, 0.2964, 0.3223, 0.3971, and 0.4239, respectively. In spatial terms, the economy system showed a distribution of “high in the east and low in the west”. (2) YRD’s EEQ indicated a gradual upward trend (from 0.3590 in 2000 to 0.3970 in 2020), with a change trend value of 0.0020 a−1. Spatially, the regions with high ECEI were mainly located in southwestern counties. (3) In the past 20 years, the CCD between economic and eco-environment systems showed an increased change trend, with a change trend value of 0.0302 a−1. The average CCD values for the five periods were 0.3992, 0.4745, 0.4633, 0.5012, and 0.5369. The overall level of CCD improved from “moderate incoordination” to “low coordination”. (4) Both NTDI and ECEI indexes have a positive effect on the improvement of regional CCD. However, the contribution of NTDI is a little higher than that of ECEI.
Factors Related to the Compliance of Arab Parents in Israel to the Vaccination of Children and Adolescents against COVID-19
Authors: Ali-Saleh Ola , Khatib Mohammad , Hadid Salam , Dahamsheh Kamal , Basis Fuad
Published: September 2023

The Arab minority consists of 20% of the Israeli population. Most of the Arab minority live in rural villages, mostly in closed communities, with specific psycho-social and sociodemographic characteristics. Previous studies showed different attitudes to COVID-19 vaccination among Arab adults. Objectives: To examine the influence of factors on the willingness of parents to vaccinate their young and adolescent children and if there is a difference between parents’ attitudes to both groups. Methods and Materials: The survey examined correlations between variables and attitudes toward the vaccine and the pandemic and was disseminated anonymously to parents of children between the ages of 5 and 18 in the Arab population of Israel through social media networks, using the snowball method. Statistical analyses included the Pearson correlation, MANCOVA, and logistic regression tests. Results: In total, 361 Arab Israeli parents participated. As mentioned above, 130 parents had both children and adolescents. Overall, 48 parents (36.9%) chose not to vaccinate both their children and adolescents, 52 parents (40.0%) chose to vaccinate only their adolescents, only 1 parent (0.8%) chose to vaccinate only the child, and 29 parents (22.3%) vaccinated both their children and adolescents. Significant correlations were found among a higher age of parents and socioeconomic status, attitudes toward COVID vaccination, subjective norms, perceived severity of the disease, perceived benefits of vaccination, and trust in formal sources. Discussion: There is a difference between parents’ decision to be vaccinated and their willingness to vaccinate their children. There is a difference between their decision to vaccinate their adolescents and their young children. Different factors positively or negatively influenced parents’ decisions. Addressing these factors by authorities may increase compliance of Arab minorities with instructions in the future.