bluuebunny/crossref_metadata_2025 huggingface dataset:
Early Diagnosis of Cognitive Impairment in Mild TBI
Authors: Mandala Giorgio
Published: May 2023

Background: Traumatic brain injury (TBI) is the first cause of death and disability in the young and active population. In the context of TBI, Mild Traumatic brain Injury (m-TBI) is frequent and it is often associated with transient cognitive disorders. Aim: The aim of this study was to promote the early diagnosis of cognitive and behavioral disorders in patients with m-TBI and to prevent under-diagnosed and long-term symptoms, reducing the risk of a decline in patient’s quality life. Design: A Longitudinal observational study was conducted on subjects who received diagnosis of mTBI in emergency department along a period of time between October 2018 and June 2021. Setting: Patients were primarily evaluated in Emergency Department of the Buccheri La Ferla Hospital in Palermo. Rehabilitation and follow-ups were conducted in Rehabilitation Medicine Complex Operative Unit of the same medical center. Population: 520 patients were registered with a diagnosis of Head Trauma in Emergency Rooms during the observational period. 65 patients (12, 5%) had a diagnosis of non-commotional head injury and therefore the possibility of being part of the study. 49 patients were included, 9 patients were excluded, 4 patients refused to be part of the study. The average age was 46, 7 years. Methods: a first neuro-psychological evaluation of the patient with m-TBI was conducted within 48 hours of the event. Anamnestic data were collected and standardized neuro-psychological screening tests were administered. Patients were followed up by a team of doctors and neuro-psychologists for a period of 12 months in order to monitor cognitive and behavioral condition. Patients with a cognitive deficit underwent to neuro-psychological rehabilitation. Results: 41% of the patients showed cognitive deficits, especially in executive functions. Patients who underwent to neuro-psychological rehabilitation obtained a normal profile at subsequent follow-up evaluations. Conclusion: m-TBI can cause different clinical manifestations. Therefore, a multidisciplinary intervention is important in order to recognize the patients most at risk of developing long-term cognitive symptoms that can compromise social and occupational functioning. Clinical Rehabilitative Impact: Post-trauma neuropsychological evaluation allows for early recognition of cognitive disorders. Neuro-psychological rehabilitation improves the quality of life of patients and reduces healthcare cost.
Reflections on the heuristic power of Contemplative Art in teaching and research
Authors: Morgan Patricia
Published: May 2023

In this article I discuss the heuristic power of combining contemplative and creative practices using different stages of my research into learning through contemplation. This began with a realisation I had, in my first meditation retreat, about the similarities between creative and contemplative consciousness. It initiated twenty-three years of applied and theoretical research that started with contemplative art workshops I ran in rehabilitation centres. In PhD research that followed I tested a hypothesis of learning through contemplation founded on the concept of an elemental ground of learning that contained an integrating force I termed the feeling nexus. In later research examining the egress of meaning where practitioners return from contemplation, I discovered that art-making can act as a bridge between pre-conceptual knowing and cognitive assimilation of that knowledge. Recently I created the Meditative Process Art (MPA) method that engages the heuristic power of combining creative and contemplative practices.
Holistic Learning Theory: More than a Philosophy
Authors: Johnson Andrew
Published: May 2023

An educational philosophy identifies and clarifies a set of values and understandings with respect to education that are based on a set of beliefs. A theory is a way to explain a set of facts and understand phenomena. Philosophies are conceptual. Theories are practical. Holistic education is a philosophy of education; however, it is also a robust theory of learning that should be included with the other theories of learning. This article describes holistic education as an educational theory.
From Factory Schooling to Nai Taleem: A Paradigm Shift in Education
Authors: Jain Manish
Published: May 2023

The article invites readers to question and reflect on the purpose of modern education and narratives of a good life, success and happiness. Modern, capitalistic, industrialized, urbanized and colonial (and colonizing) ways of living and being have created numerous global challenges. In light of these challenges, we need to re-examine our educational systems. I explore the potential of nai taleem as a philosophy of learning, living, and being; one that decolonizes education, our monoculture mindsets, and our notions of a good life. In an increasingly globalized, albeit disconnected, world I call for nai taleem as a means for building meaningful connection with oneself, with the community, and with the larger (natural) world. I share four case studies of interventions where I applied nai taleem based philosophies to a mainstream government-run school, a higher education initiative, a translocal learning network, and to my own daughter’s education. Finally, I share a reflective oath for educators as a commitment to exploring unlearning and nai taleem.
From Without to Within: Inner Transformation as a Pedagogy for Social Activism
Authors: Wu Jinting
Published: May 2023

Change has become the urgency of our time, as the harrowing Anthropocene and ongoing socio-political crises are challenging the future of humanity and our planet. While systemic structural forces are often (and rightfully so) the target to blame, social activism is as much about our own path of inner change as it is about attempting to create a better world externally. This aspect of social activism can easily become misunderstood as inertia, while more traditional forms of resistance aimed at subverting macro-structures are favored. In this essay, I draw from literature on spirituality and consciousness, new biology, quantum sciences, as well as nature studies and education, to shed light on a new form of social activism that calls for each person to recognize our role in co-creating the world, and emphasizes spiritual awakening as the most vital feature of human flourishing. Social change in the external domain will not last unless we have done the inner work to weed out misconceptions, biases, and wrong thinking that led us to contemporary crises in the first place. The essay discussed the elevation of human consciousness through the aid of nature and yogic sciences as the need of the hour, and as the most crucial aspects of social activism in the new era.
Reincorporación y tránsitos hacia la paz: Los casos de los Espacios Territoriales de Capacitación y Reincorporación (ETCR) de Tierra Grata y Pondores
Authors: Sánchez Salcedo José Fernando , Díaz Jordán Ana María , Hetzer Andreas , Dießelmann Anna-Lena , Schnettler Bernt , Pach Helen , Bastidas Meneses Luis Bernardo
Published: May 2023

A pesar de la importancia de este proceso para la paz del país, salvo los informes institucionales y lo que los medios de comunicación difunden, poco se sabe del proceso de reincorporación y del modo cómo los dife­rentes grupos de desmovilizados se han ido adaptando a los espacios territoriales y adelantando proyectos que les permitan asegurar su per­manencia en los territorios en los que se han instalado. El propósito de este libro es realizar una aproximación al proceso de rein­corporación de los excombatientes de las FARC-EP que han permanecido en los ETCR, mediante un análisis que parta del punto de vista de las per­cepciones de los actores y de sus conductas frente a la reincorporación. Esta estrategia metodológica supuso la realización de visitas a las zonas, observación de actividades cotidianas y entrevistas a los habitantes de los ETCR de Tierra Grata (César) y Pondores (Guajira). Todas estas acti­vidades estuvieron acompañadas de registros audiovisuales y ejercicios de video análisis. Entre los principales hallazgos que muestra este estudio es que el pro­ceso de reincorporación ha sido una tensión entre dos percepciones de la reincorporación, una de corte individualista promovida por la agencia para la reincorporación, y una segunda, colectivista, desarrollada por los excombatientes de las FARC-EP. Esta última caracterizada, por nuevas formas de organización política como el partido de las FARC (Fuerza Al­ternativa Revolucionaria del Común, hoy Comunes), consejos y comités políticos en los espacios territoriales, así como la creación de juntas de acción comunal han contribuido de manera decisiva en la permanencia en los ETCR, así como en el desarrollo de proyectos como la creación de un programa de vivienda para sus habitantes y el mejoramiento de servi­cios como el suministro de agua. La utilización de técnicas visuales como el video y la fotografía fueron centrales para captar la cotidianidad de la vida en los Espacios Territoria­les y, también, se convirtieron en un importante mecanismo de socializa­ción y reflexión conjunta con los firmantes de paz, sobre los principales temas y problemas de la reincorporación.
EXPERIÊNCIAS SOBRE ALEITAMENTO MATERNO ENTRE MÃES RESIDENTES EM MUNICÍPIO PARAIBANO
Authors: Galdino Lívia Ferreira Cirilo , Andrade Smalyanna Sgren da Costa , De Queiroz Viviane Cordeiro , De Lucena Adriana Lima Rufino , Pereira Vagna Cristina Leite da Silva , Oliveira Simone Helena dos Santos
Published: May 2023

Objetivo: avaliar a experiência de mães residentes em município paraibano sobre aleitamento materno. Método: nota prévia de um projeto guarda-chuva, de corte transversal, realizado com 252 mães, através de questionário virtual, por meio do Google Forms. Resultados: a principal motivação para continuidade do aleitamento materno exclusivo foi vínculo entre mãe e filho (23,4%) e a principal barreira foi o retorno ao trabalho (16,8%). Os três principais recursos de ingestão que provocaram a percepção do aumento do aleitamento materno foram sucos cítricos (21,2%), água (19,5%) e frutas diversas (7%). A maioria ingeriu até dois litros de água (46,4%), a substância mais eliciada para favorecer o volume de leite foi a tintura de algodoeiro (12,3%) e o método mais referido para aumento da produção foi a ordenha manual (63,6%), sendo problemas emocionais (40,5%) o maior motivo para a redução do leite. Sobre a ingestão de alimentos que porventura poderiam provocar gases, foram chocolate (27,6%), refrigerante (17,6%) e café (15%) os mais eliciados. Conclusão: acredita-se que este estudo traz contribuições a área materno-neonatal, bem como aos profissionais de saúde, pois incita o debate acerca dessa temática, de maneira que possibilita a ampliação do conhecimento e permita uma reflexão sobre as ações de promoção e apoio a amamentação, em busca da intersetorialidade e interdisciplinaridade, visando a redução nas taxas de desmame precoce.
AURICULOTERAPIA: TRATAMENTO COMPLEMENTAR EM ATLETAS COM LESÃO DE ESFORÇO REPETITIVO – ESTUDO PILOTO
Authors: Westphal Camila Michelle , Garcia Ítalo Ruami , Gonçalves Ariane Jamyle Rogério , Valente Caroline
Published: May 2023

Introdução: a auriculoterapia objetiva a estimulação de pontos na orelha visando o reequilíbrio das energias, acarretando melhora de patologias. As lesões por esforço repetitivo (LER) são frequentemente encontradas na realidade de um atleta de alto rendimento, deste modo, a busca por tratamentos diferenciados e eficazes para auxiliar na recuperação das lesões possibilita a inserção de técnicas diferenciadas, a exemplo das técnicas complementares. Objetivo: o estudo objetiva avaliar a eficácia da auriculoterapia como tratamento complementar em LER. Métodos: trata-se de um estudo piloto, experimental, não randomizado e não cego. A pesquisa foi realizada com 10 atletas de alto rendimento, da Fundação Municipal de Desportos da cidade de Blumenau-SC, divididos em dois grupos, um grupo recebeu tratamento de fisioterapia convencional e auriculoterapia e o outro apenas fisioterapia convencional. Participaram atletas de ambos os sexos e de diferentes modalidades. As avaliações foram realizadas semanalmente após os atendimentos, utilizando questionário para avaliação de dor, sintomas e utilização de medicações. Para auxiliar a avaliação, foram realizadas imagens por termografia para avaliação do processo inflamatório, as fotos foram realizadas antes e após o tratamento. Resultados: os resultados encontrados sugerem melhora em ambos os grupos, todavia, o grupo onde houve associação da fisioterapia convencional e auriculoterapia apresentou melhoras significantes em relação ao outro grupo, além disso, apresentaram redução no uso de medicações e diminuição no processo inflamatório avaliado pela termografia. Conclusão: a auriculoterapia se mostrou um importante aliado ao tratamento convencional e pode ser uma opção para tratamento complementar em LER.
Petrographic and geochemical evidence of calc-silicate xenolith – magma interaction in the western Bushveld Complex, South Africa
Authors: Koovarjee B. , Gibson R.L. , Nex P.A.M.
Published: May 2023

Underground workings at Rowland Shaft, Lonmin Platinum, near Marikana have exposed a large (>7 x 5 m) calc-silicate xenolith in mottled anorthosite ~20 m below the UG 1 chromitite of the upper Critical Zone. The xenolith comprises a monticellite + forsterite + spinel assemblage that is consistent with a metamorphic Tmax of ≥975°C being reached at P ~1 kbar and XCO2 ~1. Internal variations in the modal proportions of these phases are interpreted as an artefact of sedimentary layering in the xenolith. The xenolith is ﬂanked by a 20 to 30 cm wide magmatic skarn that contains several small, cm- to dm-scale, calc-silicate fragments displaying the same peak assemblage as the main xenolith, as well as a dm-scale chromitite autolith and mm- to dm-scale lenses and stringer-like masses of ﬁne-grained uvarovite. The skarn matrix is mineralogically zoned, with an up to 10 cm wide clinopyroxenite layer proximal to the xenolith contact and calc-silicate fragments grading outwards into a gabbroic, plagioclase-clinopyroxene assemblage in which plagioclase becomes progressively more dominant distally. Notwithstanding its pseudo-ophitic texture, the distal skarn matrix displays a range of features consistent with crystallisation of magma contaminated by Ca from the decomposing xenolith under elevated fO2 conditions, including: (a) the unusual mineral compositions (zoned aluminian-ferrian diopside and anorthite, An>99), (b) the presence of calcite as inclusions in plagioclase and as a minor interstitial phase, (c) corroded wollastonite inclusions in clinopyroxene, and (d) thin grossular reaction rims between clinopyroxene and plagioclase. This chemical evolution is further substantiated by zoned spinel grains comprising Cr-rich cores and Al-enriched rims, which are, in turn, enclosed in garnet aggregates that grade outwards from uvarovite to grossular. Local development of grossular-vesuvianite symplectite indicates limited retrograde hydrous (XCO2 <0.1) ﬂuid inﬂux under subsolidus conditions (T <750°C). Bedding in the xenolith displays a steep westerly dip, approximately orthogonal to the magmatic layering. This, together with evidence in the skarn of both plastic shear strain and out-of-sequence magmatic autoliths, suggests that the xenolith underwent density-driven foundering within the RLS magma from an initial location above the UG 1 chromitite layer.
Long-pulsed 1064 nm Nd: YAG laser in treatment of palmoplantar warts: A prospective study
Authors: Rana Prangya Parimita , Mysore Venkatram
Published: May 2023

Objectives:

Palmoplantar warts are a challenge to treat. Standard treatment methods include electrocautery, radiofrequency ablation and cryosurgery, carbon dioxide laser, and Erbium-doped Yttrium Aluminum Garnet laser, which are ablative, invasive, and have downtime. Non-ablative lasers like pulsed dye laser and long-pulsed Neodymium: Yttrium-Aluminum-Garnet (Nd: YAG) have been tried earlier for the treatment of warts to overcome these deficiencies. The aim of the study was to assess the efficacy and safety of long-pulsed 1064 nm Nd: YAG laser in the treatment of palmoplantar warts.

Material and Methods:

Eleven adult subjects with a total of 58 hand and foot warts were enrolled in the clinical trial from January 2016 to January 2017 to receive treatment with long-pulsed 1064 nm Nd: YAG laser. The thick hyperkeratotic part of the wart was removed by paring and then the lesion was treated, at monthly intervals for four sessions or until the clearance of the warts. Response was assessed at the beginning, before each treatment session and after the final treatment.

Results:

A total of 8 subjects with 52 warts completed the study. Forty (76.9%) warts showed complete clearance of lesion and 2 (3.8%) warts showed marked improvement. Ten (19.2%) warts did not get cleared. The average number of sessions was 2.2. Mild pain was noticed during the procedure. There was no wound, no infection and no bandages were required after the procedure. Post-inflammatory pigmentation or scarring was not observed in any case.

Conclusion:

Long-pulsed 1064 nm Nd: YAG laser is safe, effective, non-destructive, and relatively painless for the treatment of palmoplantar warts.
Rapid expansion of post traumatic syringomyelia following parathyroidectomy: A case report and review of the literature
Authors: O’Connor Hunter A. , Thanel Paul F. , Dirks Shouri K. , Alchaki Abdul R.
Published: May 2023

Background:

Post-traumatic syringomyelia (PTS) is an uncommon complication of spinal cord injury (SCI) characterized by development of a fluid filled cavity in the spinal cord parenchyma. Presentation involves pain, weakness, and abnormal reflexes. There are few known triggers for disease progression. We present a case of symptomatic PTS that appears to have been triggered by parathyroidectomy.

Case Description:

A 42-year-old female with a distant history of SCI developed clinical and imaging findings consistent with acute expansion of PTS immediately following parathyroidectomy. Her symptoms included acute numbness, tingling, and pain in both arms. Magnetic resonance imaging (MRI) revealed a syrinx in the cervical and thoracic spinal cord. However, this was initially misdiagnosed as transverse myelitis and was treated as such without resolution of symptoms. Over the following 6 months, the patient experienced progressive weakness. Repeat MRI demonstrated expansion of the syrinx with new involvement of the brain stem. The patient was diagnosed with PTS and referred for outpatient neurosurgery evaluation at a tertiary facility. Treatment was delayed due to problems with housing and scheduling at the outside facility, allowing for continued worsening of her symptoms. The syrinx was surgically drained and a syringo-subarachnoid shunt was placed. Follow-up MRI confirmed correct placement of the shunt as well as resolved syrinx and decreased thecal sac compression. The procedure effectively halted symptom progression but did not resolve all symptoms completely. The patient has regained her ability to perform much of her activities of daily living but remains in a nursing home facility.

Conclusion:

There are currently no cases of PTS expansion following non-central nervous system surgery reported in the literature. The reason for PTS expansion following parathyroidectomy in this case is unknown but may highlight the need for extra caution when intubating or positioning a patient with a history of SCI.
Neurosurgical intervention in an unusual case of extensive acute disseminated encephalomyelitis – A case report and literature review
Authors: Azab Mohammed A
Published: May 2023

Background:

The clinical presentations of demyelinating diseases are variable and can range from mild symptoms to fulminant presentations. Acute disseminated encephalomyelitis is one of those diseases which usually follow an infection or vaccination.

Case Description:

We report a case of extensive acute demyelinating encephalomyelitis (ADEM) with massive brain swelling. A 45-year-old female presented to the emergency room with status epilepticus. Patient has no history of any associated medical problems. Glasgow coma scale (GCS) was 15/15. CT brain was normal. Lumbar puncture was done and cerebrospinal fluid showed pleocytosis and increased protein content. About 2 days after admission, the conscious level rapidly deteriorated and GCS was 3/15, with the right pupil fully dilated and unreactive to light. Computed tomography and magnetic resonance imaging brain were done. We performed an urgent decompressive craniectomy as a life-saving procedure. Histopathological examination was suggestive of ADEM.

Conclusion:

Few cases of ADEM with brain swelling were reported, but there is no solid consensus about the appropriate management of these cases. Decompressive hemicraniectomy is a possible choice, but further research is needed to evaluate the proper timing, and indication of surgery.
Parametric Optimization and performance assessment of polyaniline graphene-impregnated electrode-based low-cost Microbial Fuel Cell using mixed culture obtained from Canteen wastewater
Authors: Ponmani Padmanaban , Parthiban P. , Ramanujam Mahesh , Murugaboopathy Sivanantham , Balraju Nilavu , Tewari Chetna , Sahoo Nandagopal , Das Ashutosh
Published: May 2023

The development of a high-efficiency anode is essential for the use of microbial fuel cells. The metallic conductivity, corrosion resilience, low cost of conducting polyaniline (PANI) and recycled graphene (RGn) pique our interest. In this study, PANI-RGn nanoparticles are polymerized in situ on cotton fabric wrapped with aluminium mesh as the anode for a microbial fuel cell. The MFC was designed as a dual-chambered system and the chambers are separated by a proton exchange membrane (PEM) salt bridge using canteen wastewater. The process parameters including cathodic chamber aeration, nutrient dosage, nitrogen fluxing, stirring and anode geometry, were optimized. The potential difference (mV) and these systems' current (mA) performance have been analyzed. On the use of PANI-RGn carbon cloth as electrodes, the output voltage was found to be of the order of 180mV. The system developed herewith is highly cost-effective because of the use of graphene that has been generated from waste plastic through catalytic pyrolysis. Hence, the present study revealed that a potential green energy alternative is PANI-RGn in situ polymerized cotton fabric and circular aluminium-mesh electrode in anoxic MFC.
Principles of education, upbringing and development of lyceum students new generation
Authors: Киселёва О.С.
Published: May 2023

В статье раскрываются принципы обучения, воспитания и развития обучающихся лицеев, которые могут быть положены в основу трансформации образовательной деятельности современного лицея, как школы элитного образования и развития обучающихся в направлении осознанного выбора ими будущей профессиональной деятельности, подготовка к которой осуществляется в университете в рамках непрерывного образования «лицей – классический университет». Таккак современное поколение обучающихся считается представителями цифрового поколения, их важной особенностью является то, что они полностью открыты к деятельности в цифровом пространстве. В связи с этим в работе акцентируется внимание на сочетании принципов обучения и принципов цифровой дидактики.

The article reveals the principles of education, upbringing and development of lyceums students which can form the basis for the transformation of the educational activities of the modern lyceum as a school of highend education and the development of students in the direction of their conscious choice of future professional activities, preparation for which is carried out at the university within the framework of continuing education "lyceum - classic university". Since the modern generation of students is considered to be representatives of the digital tribe, their important feature is that they are fully open to activities in the digital space. According to this the work focuses on the combination of the educational principles and the principles of digital didactics.
The state of research on the problem of lexical competence formation in Russian language lessons
Authors: Мутусханова Р.М. , Окуева Х.З. , Джанаралиева З.К.
Published: May 2023

В статье рассматриваются проблемы формирования лексической компетентности на уроках русского языка в средней школе. В концепции языкового образования школы в государственном стандарте базовой и полного среднего образования отмечено, что одним из ведущих лингводидактических подходов к изучению русского языка должен быть коммуникативнодеятельностный подход, который будет способствовать овладению лингвистическими знаниями и речевыми умениями. Преподаватели имеют все необходимые ресурсы, для современных оригинальных и креативных методик обучения лексики. Формирование лексической компетентности учащихся средней школы имеет важное значение для развития мышления и речи; способствует становлению речевой личности и подъему общей языковой культуры обучающихся.

The article deals with the problems of lexical competence formation in Russian language lessons in secondary school. In the concept of language education of the school in the state standard of basic and full secondary education, it is noted that one of the leading linguistic and didactic approaches to learning the Russian language should be a communicative-activity approach that will contribute to mastering linguistic knowledge and speech skills. Teachers have all the necessary resources for modern original and creative methods of teaching vocabulary. The formation of lexical competence of secondary school students is important for the development of thinking and speech; contributes to the formation of a speech personality and the rise of the general language culture of students.
Methodology of formation of physical culture of future teachers in the process of professional physical education
Authors: Зенченков И.П.
Published: May 2023

В статье рассматривается методология формирования физической культуры будущего учителя в процессе профессионального физкультурного образования. Методология формирования физической культуры личности основывается на четырёх уровнях методологии. Решение проблемы формирования физической культуры личности будущего учителя мы рассматривали в своём исследовании как сложное, многоуровневое явление. В статье рассмотрены методологические теории, подходы, категории и принципы. Статья посвящена разработке методологии формирования физической культуры будущих учителей в процессе профессионального физкультурного образования. В работе рассмотрены основные аспекты формирования физической культуры будущих учителей, в том числе педагогические, психологические и медико-биологические аспекты. Описаны основные этапы профессионального физкультурного образования будущих учителей, включая анализ их физического состояния, планирование и реализацию программ физической подготовки, а также оценку эффективности проводимой работы. Предложены методические рекомендации для преподавателей и студентов, способствующие эффективному формированию физической культуры будущих учителей в процессе профессионального физкультурного образования.

The article discusses the methodology of the formation of physical culture of the future teacher in the process of professional physical education. The methodology of the formation of physical culture of the individual is based on four levels of methodology. In our study, we considered the solution of the problem of the formation of the physical culture of the personality of the future teacher as a complex, multilevel phenomenon. The article discusses methodological theories, approaches, categories and principles. The article is devoted to the development of a methodology for the formation of physical culture of future teachers in the process of professional physical education. The paper considers the main aspects of the formation of physical culture of future teachers, including pedagogical, psychological and biomedical aspects. The main stages of professional physical education of future teachers are described, including analysis of their physical condition, planning and implementation of physical training programs, as well as evaluation of the effectiveness of the work carried out. Methodological recommendations for teachers and students are proposed that contribute to the effective formation of physical culture of future teachers in the process of professional physical education.
Economic consequences of the lack of equal opportunities in access to education
Authors: Тронин С.А.
Published: May 2023

Образование является ключевым фактором для развития любой страны, так как обеспечивает кадры, необходимые для развития экономики и общества в целом. Но в России существуют проблемы с доступом к образованию, которые приводят к неравенству возможностей и ущемлению прав части населения на получение качественного образования. Эти проблемы связаны с различными факторами, такими как экономическая нестабильность, ограниченность доступа к образованию в регионах, недостаток квалифицированных преподавателей и устаревшие образовательные программы. В условиях современного мира, когда качество образования становится ключевым фактором конкурентоспособности страны, необходимо активно работать над решением этих проблем. Цель настоящей статьи - проанализировать проблемы в доступе к образованию в России, исследовать их последствия для экономики страны и общества в целом, а также предложить пути решения этих проблем. В результате исследования будет представлен обзор существующей ситуации в России, а также будут рассмотрены различные методы и подходы к решению проблем в доступе к образованию. Несмотря на то, что некоторые проблемы в доступе к образованию в России уже получили некоторое внимание со стороны правительства и общественности, еще многое предстоит сделать, чтобы обеспечить равные возможности для всех учеников в стране.

Education is a key factor for the development of any country, as it provides the personnel necessary for the development of the economy and society as a whole. But in Russia there are problems with access to education, which lead to inequality of opportunities and infringement of the rights of a part of the population to receive a quality education. These problems are related to various factors, such as economic instability, limited access to education in the regions, lack of qualified teachers and outdated educational programs. In the conditions of the modern world, when the quality of education becomes a key factor of the country's competitiveness, it is necessary to actively work on solving these problems. The purpose of this article is to analyze the problems in access to education in Russia, to investigate their consequences for the country's economy and society as a whole, and to propose ways to solve these problems. As a result of the study, an overview of the current situation in Russia will be presented, as well as various methods and approaches to solving problems in access to education will be considered. Despite the fact that some problems in access to education in Russia have already received some attention from the government and the public, much remains to be done to ensure equal opportunities for all students in the country.
Reactive Docking: a computational method for high-throughput virtual screenings of reactive species
Authors: Bianco Giulia , Holcomb Matthew , Santos-Martins Diogo , Tillack Andreas , Hansel-Harris Althea , Forli Stefano
Published: May 2023

We describe the formalization of the reactive docking protocol, a method developed to model and predict reactions between small molecules and biological macromolecules. The method has been successfully used in a number of applications already, including recapitulating large proteomics datasets, performing structure-reactivity target optimizations and prospective virtual screenings. By modeling a near-attack conformation-like state, no QM calculations are required to model ligand and receptor geometries. Here, we present its generalization using a large dataset containing more than 400 ligand-target complexes, 8 nucleophilic modifiable residue types, and more than 30 warheads. The method correctly predicts the modified residue in ~85% of complexes and shows enrichments comparable to standard focused virtual screenings in ranking ligands. This performance supports this approach for the docking and screening of reactive ligands in virtual chemoproteomics and drug design campaigns.
Challenges for ab initio molecular dynamics simulations of electrochemical interfaces
Authors: Gross Axel
Published: May 2023

The modelling of electrochemical interfaces between a liquid electrolyte and an electrode from a quantum chemical perspective is typically done by performing ab initio molecular dynamics simulations. Thus the statistically nature of the electrolyte structure can be taken into account by performing the proper averages. However, in order to obtain reliable results for such electrochemical interfaces, the simulations should be performed for sufficiently large systems and sufficiently long times under potential control. These requirements lead to significant challenges for running such simulations which will be addressed in this contribution, together with possible approaches to address these challenges.
Step-induced double-row pattern of interfacial water on rutile TiO2(110) at electrochemical conditions
Authors: Sun Yan , Wu Cheng-Rong , Wang Feng , Bi Rui-Hao , Zhuang Yong-Bin , Liu Shuai , Chen Ming-Shu , Zhang Kelvin H.-L. , Yan Jia-Wei , Mao Bing-Wei , Tian Zhong-Qun , Cheng Jun
Published: May 2023

Metal oxides are promising (photo)electrocatalysts for sustainable energy technologies due to their good activity and abundant resources. Their applications such as photocatalytic water splitting predominantly involve aqueous inter- faces at electrochemical conditions, but in situ probing oxide-water interfaces is proven to be extremely challenging. Here, we present an electrochemical scanning tunneling microscopy (EC-STM) study on the rutile TiO2(110)-water interface, and by tuning surface redox chemistry with careful potential control we are able to obtain high quality images of interfacial structures with atomic details. It is interesting to find that the interfacial water exhibits an unexpected double-row pattern that has never been observed. This finding is confirmed by performing a large scale simulation of a stepped interface model enabled by machine learning accelerated molecular dynamics (MLMD) at ab initio accuracy. Furthermore, we show that this pattern is induced by the steps present on the surface, which can propagate across the terraces by interfacial hydrogen bonds. Our work demonstrates that by combining EC-STM and MLMD we can obtain new atomic details of interfacial structures that are valuable to understand the activity of oxides at realistic conditions.
Online Buffer Exchange Enables Automated Membrane Protein Analysis by Native Mass Spectrometry
Authors: Liu Weijing , Jayasekera Hiruni , Sanders James , Zhang Guozhi , Viner Rosa , Marty Michael
Published: May 2023

Membrane proteins represent the majority of clinical drug targets and are actively involved in a range of cellular processes. However, the complexity of membrane mimetics for membrane protein solubilization poses challenges for native mass spectrometry (MS) analyses. The most common approach for native MS analyses of membrane proteins remains offline buffer exchange into native MS-compatible buffers prior to manual sample loading into static nano-ESI emitters. This laborious process requires relatively high sample consumption and optimization for individual proteins. Here, we developed online buffer exchange coupled to native mass spectrometry (OBE-nMS) for analyzing membrane proteins in different membrane mimetics, including detergent micelles and nanodiscs. Detergent screening for OBE-nMS reveals mobile phases containing ammonium acetate with lauryl-dimethylamine oxide is most universal for characterizing both bacterial and mammalian membrane proteins in detergent. Membrane proteins in nanodiscs simply require ammonium acetate as the mobile phase. To preserve the intact nanodiscs, a novel switching electrospray approach was used to capture the high-flow separation on column with a low-flow injection to MS. Rapid OBE-nMS completes each membrane protein measurement within minutes and thus enables higher-throughput assessment of membrane protein integrity prior to its structural elucidation.
A supervised classification phenotyping approach using machine learning for patients diagnosed with primary breast cancer
Authors: Bashir Ahmad , Burhan Ullah , Fouzia Sardar , Hazrat Junaid , Gul Zaman Khan
Published: May 2023

This paper presents a methodology for the early detection and diagnosis of breast cancer using the Wisconsin dataset. The methodology involves four main steps, including data collection, preprocessing, feature selection, and classification. Fine needle aspiration technique is used to extract the ultrasound image features of breast cancer, and preprocessing is performed to eliminate outliers, null values, and noise. Redundant parameters are removed during the feature selection process to improve accuracy. Six machine learning algorithms, including Logistic Regression, Support Vector Machine, K-Nearest Neighbor, Random Forest, Decision Tree, and Gaussian Naive Bayes, are employed for the classification of the breast cancer dataset. Support Vector Machine and K-Nearest Neighbor achieved the highest accuracy, with Logistic Regression, Gaussian Naive Bayes, Random Forest, and Decision Tree having lower accuracy scores. The proposed methodology could aid in the timely detection and diagnosis of breast cancer, and help doctors in selecting the optimal clinical treatment plan for their patients. Further work will be carried out to investigate the effectiveness of additional preprocessing algorithms in improving the classification accuracy of the breast cancer dataset.
Design and development of accessible video chat application for people with disabilities
Authors: Ninad Patil , Siddhesh Mane , Akash Maurya , Zahir Aalam
Published: May 2023

Communication has been a struggle for everyone since the covid outbreak and in the aftermath, people have had to get accustomed to video conferencing applications. However people with physical or mental limitations are still unable to use video conferencing apps and their interfaces. This necessitates the development of web-based video chat applications. These applications can aid those who are unable to communicate verbally and/or operate using standard mouse and keyboard inputs, but yet need to feel close to others when they are apart. The proposed application incorporates various accessibility features such as speech-to-text and text-to-speech, gaze tracking and pictorial speech interfaces. It enables individuals with disabilities to participate in virtual meetings on an equal footing with their peers. The goal is to remove barriers and promote inclusiveness in remote work and collaboration for all users, regardless of their abilities using this application.
Intersection graph of subgroups of some non-abelian groups
Authors: R. Rajkumar  , P. Devi
Published: May 2023

The intersection graph of subgroups of a group $G$ is a graph whose vertex set is the set of all proper subgroups of $G$ and two distinct vertices are adjacent if and only if their intersection is non-trivial. In this paper, we obtain the clique number and degree of vertices of intersection graph of subgroups of dihedral group, quaternion group and quasi-dihedral group.
Results on weighted stepanov-like pseudo periodic functions and applications
Authors: Shan Zheng
Published: May 2023

In this article, we first established some new results on composition of weighted Stepanov-like pseudo periodic function of class $r$ under a uniform continuity condition with respect to $L^p$ norm. And then, we proved the existence and uniqueness of weighted pseudo periodic solutions to a semi-linear functional differential equation with finite delay under Stepanov-like nonlinear term.
Intuitionistic filter
Authors: R.Raja Rajeswari  , K. Suguna Devi  , N.Durga Devi
Published: May 2023

The aim of this paper is to introduce a intuitionistic filter and study some of its properties.
ПЕРЕКЛАДАЦЬКІ ТРАНСФОРМАЦІЇ ТА ПРИЙОМИ: ТЕРМІНОЛОГІЧНІ ВИКЛИКИ У ПЕРЕКЛАДОЗНАВСТВІ
Authors: Козачук А. М.
Published: May 2023

Стаття стосується проблеми термінологічних невідповідностей в українських та англомовних перекладознавчих дослідженнях, які зумовлені різницею у відповідних наукових традиціях. Увагу, зокрема, приділено зіставленню термінологічного сегменту, що стосується перекладацьких трансформацій в українському перекладознавстві і перекладацьких технік – в англомовному. Традиційно перекладацькими трансформаціями називають прийоми, що передбачають перетворення одиниць тексту оригіналу в одиниці тексту перекладу (О. Селіванова). Досить великою підтримкою користується класифікація трансформацій, до якої входять: додавання, вилучення, перестановка і заміна. Саме заміна є найчастіше вживаною трансформацією у перекладі. Особливим різновидом заміни є компенсація, до якої вдаються у разі неможливості створення необхідного стилістичного ефекту аналогічними засобами мови перекладу. Також побутує думка про те, що трансформації використовуються переважно у комплексі, а не у чистому вигляді. В англомовному перекладознавчому дискурсі термін «перекладацькі трансформації» не використовується, натомість в емпіричних дослідженнях широкого поширення набув термін «перекладацькі прийоми» (англ. – translation techniques). Так само, як і у випадку з трансформаціями, не існує єдиної уніфікованої класифікації перекладацьких прийомів, хоча найвідоміші з них засновані здебільшого на концепції П. Ньюмарка. У статті детально аналізується класифікація прийомів, до якої входять: адаптація, посилення, запозичення, калька, компенсація, опис, дискурсивне створення, усталений еквівалент, узагальнення, лінгвістичне посилення, лінгвістичне стиснення, буквальний переклад, модуляція, уточнення, скорочення, заміна, перестановка і варіація (Л. Моліна, А. Албір). У результаті проведення паралелей між двома терміносистемами, зокрема, встановлено відповідність: адаптація ‒ локалізація, посилення ‒ додавання, запозичення ‒ транскодування, дискурсивне створення ‒ контекстуальний переклад, лінгвістичне посилення ‒ декомпресія, лінгвістичне стиснення ‒ компресія, модуляція ‒ (в низці випадків) антонімічний переклад, уточнення ‒ конкретизація, скорочення ‒ вилучення, перестановка ‒ заміна.
СЛОВОТВІРНА СУФІКСАЦІЯ ЯК МАРКЕР МЕХАНІЗМУ ДІЄСЛІВНОСТІ У СТАРОУКРАЇНСЬКІЙ МОВІ ПИСЕМНИХ ПАМ’ЯТОК XIV–XVII СТ.
Authors: Кочерга Г. В.
Published: May 2023

У статті схарактеризовано староукраїнські відіменникові деривати за структурно-ономасіологічними і мотиваційними процесами, а тип мотивації, її різновид та компонент, вербалізований в ономасіологічній ознаці відіменникових дієслів, визначає семантичну групу предикатів, позначених дієслівними одиницями. Мотиваційні процеси староукраїнських відіменникових дієслів із суфіксами -ова-,(˃-ува-/,- юва-,-ева-///-ева-/) простежуються як у пропозиційно-диктумній, так і в асоціативно-термінальній мотивації. Пропозиційно-диктумна мотивація староукраїнських відіменникових дієслів є найбільш поширеною у дієслівній системі XIV–XVII ст., мотиватори дієслів вибираються зі сфери предикатно-аргументної структури концепту і мають прямі значення. З’ясовано асоціативно-термінальну мотивацію відіменникових дериватів у дієслівній системі староукраїнської літературної мови, що простежується на виборі мотиватора з компонента неістинних, метафоричних знань. У дієслівному словотворі староукраїнської літературної мови виокремлюються модусно мотивовані відіменні деномінативи, що характеризуються використанням оцінного сприймання мотиваторів мовцями. Словотвірно-ономасіологічний механізм творення відіменних дієслів у писемних пам’ятках XIV–XVII ст. є вербальним і граматикалізованим позначенням предикатної позиції концепту на підставі селекції одного із субстанційних компонентів пропозиції або його асоціата, висвітлених у певній когнітивній структурі ситуації шляхом внутрішнього програмування з огляду на структуру свідомості носіїв мовної картини світу.
АРХІТЕКТОНІКА ЗВУКОВИХ РЕПРЕЗЕНТАЦІЙ У МЕЖАХ КОГНІТИВНОГО НАПРЯМУ ФОНЕТИЧНИХ ДОСЛІДЖЕНЬ
Authors: Красовська І. В.
Published: May 2023

У статті розглядається центральне та дискусійне поняття для сучасних фонетичних досліджень – звукова репрезентація. Обґрунтовано доцільність аналізу природи звукових репрезентацій у межах когнітивного підходу, основні засади якого орієнтують фонетистів на вивчення сегментної й надсегментної систем мови як невід’ємних складників мисленнєвої діяльності людини, що тісно взаємодіє з іншими когнітивними структурами та процесами: сприйняттям, увагою, пам’яттю. Природа звукових репрезентацій аналізується, спираючись на когнітивні операції, що забезпечують сприйняття та декодування звукового повідомлення. Представлено структурований огляд накопиченого у фонетиці матеріалу, що свідчить про наявність релевантних зв’язків сегментного й надегментного рівнів мови з ментальними процесами у свідомості мовця. Запропоновано класифікацію існуючих експериментально-фонетичних підходів до вивчення когнітивних процесів сприйняття звукової інформації: артикуляційний, акустичний та акустико-візуальний. Виокремлення зазначених підходів зроблено, ураховуючи когнітивні операції кодування та зберігання звукової інформації у свідомості мовця, які дослідники розглядають як фундаментальні для виникнення системи звукових репрезентацій у свідомості мовця з подальшим їх використанням для побудови власних висловлень під час мовленнєвої комунікації. Представлено узагальнену класифікацію різних підходів до архітектури звукових репрезентацій, які розглядаються як складова частина мисленнєвої діяльності людини, що виникають унаслідок взаємодії з когнітивними процесами мовця. З огляду обґрунтованої глибинної структури звукової репрезентації у межах зазначених підходів, вони поділені на дві укрупнені групи, а саме: одноформатні та поліформатні. Звукові репрезентації, які класифіковано як одноформатні, виникають у психоакустичному просторі завдяки активації вроджених акустичних ключів. Формування поліформатних репрезентацій розглядається як динамічний процес, що охоплює декілька стадій, на кожній із яких з’являється певна когнітивна структура, що відбиває синтез звукової інформації на цьому етапі когнітивної діяльності. Архітектоніка формування звукових репрезентацій представлена як рухливий процес, що розгортається у певному мовленнєвому контексті, активується акустичними ключами, у результаті чого у свідомості мовця поетапно з’являються ментальні структури зберігання звукової інформації.