bluuebunny/crossref_metadata_2025 huggingface dataset:
On the Potential Mismatch Between the Function of the Bayes Factor and Researchers’ Expectations
Authors: Wong Tsz Keung , Kiers Henk , Tendeiro Jorge
Published: June 2022

The aim of this study is to investigate whether there is a potential mismatch between the usability of a statistical tool and psychology researchers’ expectation of it. Bayesian statistics is often promoted as an ideal substitute for frequentists statistics since it coincides better with researchers’ expectations and needs. A particular incidence of this is the proposal of replacing Null Hypothesis Significance Testing (NHST) by Null Hypothesis Bayesian Testing (NHBT) using the Bayes factor. In this paper, it is studied to what extent the usability and expectations of NHBT match well. First, a study of the reporting practices in 73 psychological publications was carried out. It was found that eight Questionable Reporting and Interpreting Practices (QRIPs) occur more than once among the practitioners when doing NHBT. Specifically, our analysis provides insight into possible mismatches and their occurrence frequencies. A follow-up survey study has been conducted to assess such mismatches. The sample (N = 108) consisted of psychology researchers, experts in methodology (and/or statistics), and applied researchers in fields other than psychology. The data show that discrepancies exist among the participants. Interpreting the Bayes Factor as posterior odds and not acknowledging the notion of relative evidence in the Bayes Factor are arguably the most concerning ones. The results of the paper suggest that a shift of statistical paradigm cannot solve the problem of misinterpretation altogether if the users are not well acquainted with the tools.
Optical and radiation shielding properties for novel glass material: TeO2/Nb2O5/Ta2O5/La2O3
Authors:   Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia, Hussein K. I. , Alqahtani F. F. ,   cDepartment of Radiological Sciences, College of Applied Medical Sciences, Najran University, Najran 1988, Saudi Arabia, Alqahtani M. S. ,   Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia, Alzahrani K. J. ,   Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia, Zahran H. Y. ,   Physics Department, Faculty of Science, King Khalid University, Postcode: 9004, Zip code: 61413, Abha, Saudi Arabia, Alshehri A. M. ,   Physics Department, Faculty of Science, King Khalid University, Postcode: 9004, Zip code: 61413, Abha, Saudi Arabia, Yahia I. S. ,   Physics Department, Faculty of Science, King Khalid University, Postcode: 9004, Zip code: 61413, Abha, Saudi Arabia, Reben M. ,   Faculty of Materials Science and Ceramics, AGH – University of Science and Technology, al. Mickiewicza 30, 30-059 Cracow, Poland, Alqahtani A. M. ,   Medical and Clinical Affairs Department, King Faisal Medical City, Abha 62523, Saudi Arabia, Yousef E. ,   Physics Department, Faculty of Science, King Khalid University, Postcode: 9004, Zip code: 61413, Abha, Saudi Arabia
Published: June 2022

Glass samples with (86-x)TeO2 – 12Nb2O5- x(Ta2O5) -1.0La2O3 where 𝑥 = 1.0 (glass TNTL1), 5.0 (glass TNTL2), 8.0 (glass TNTL3), and 10 (glass TNTL4) mol% composition were synthesized by a melt quenching technique. The gammaray attenuation parameters of TNTL system such as MAC, LAC, HVL, MFP, Zeff, and Neff were analyzed in this study in order to better understand the effect of Ta2O5 on photon absorption.Within the 190-2500-nm wavelength range, the optical properties of prepared TNTL glasses were also evaluated. It was observed from the optical absorption spectra that all glass samples studied had good optical transparency. The findings indicated that adding Ta2O5 to glass enhances the gamma protection ability as well as the optical properties. The densities of the samples ranged from 5.66 to 6.49 g/cm3, depending on the Ta2O5 concentration. Sample TNTL4 had the best preformace, according to the results recorded.
Effect of Au and Ag nanoparticles addition on the morphological, structural and optical properties of ZnO thin films deposited by sol-gel method
Authors:   Department of Physics, College of Science, University of Diyala, Diyala, Iraq, Kamil A. A. , Bakr N. A. ,   Department of Physics, College of Science, University of Diyala, Diyala, Iraq, Mubarak T. H. ,   Department of Physics, College of Science, University of Diyala, Diyala, Iraq, Al-Zanganawee J. ,   Department of Physics, College of Science, University of Diyala, Diyala, Iraq
Published: June 2022

In the present study, ZnO thin films were deposited on quartz substrates by sol-gel spincoating method. Zinc-diacetate ((Zn(CH3COO)2.2H2O), diolamine (DEA) (HN(CH2CH2OH)2) and ethylene glycol monomethyl ether (CH3OCH2CH2OH) were used as a precursor, stabilizer agent, and solvent, respectively. Au and Ag NPs were synthesized by (PLAL) technique using “Q-Switched ND-YAG laser” system with laser parameters (520 mJ laser energy, 1064 nm wavelength, 450 laser pulses, and 1Hz frequency). The volumetric ratios of ZnO source solution to Au and Ag colloidal solutions were 3:2 and 4:1, respectively. The morphological, structural and optical properties of ZnO thin films embedded with Au and Ag NPs were investigated. The patterns of x-ray diffraction (XRD) showed peaks indexed to (100), (002) and (101) planes for ZnO and (111), (200) and (220) for Au and Ag NPs. The surface morphology of the films was examined by FESEM and the Raman spectra of ZnO thin films embedded with Ag and Au NPs were investigated. Furthermore, the optical properties of the films were analyzed by UV-Vis spectroscopy measurements. The optical band gap of the films increased with increasing the volumetric ratios of ZnO embedded with Au and Ag NPs.
Features of intercellular interaction of platelets and neutrophils expressing adhesion molecules in psoriasis
Authors: Sherstennikov Nikolay V. , Kashutin Sergey L. , Sherstennikova Alexandra K. , Kalmin Oleg V. , Nikolaev Valentin I.
Published: June 2022

Objective: to determine the features of intercellular interaction of platelets with neutrophils expressing adhesion molecules in psoriasis patients.
Material and Methods. The study included 82 patients 20-60 years of age with a plaque psoriasis or pustular psoriasis. As a control group, 50 virtually healthy individuals 20-60 years old were examined. The study of the adhesion molecules spectrum on neutrophils was carried out on a Beckman Coulter FC-500 flow cytometer (USA) using monoclonal antibodies. The platelet-neutrophil aggregates were determined sensu the method by Yu.A. Vitkovsky et al. (2006).
Results. In patients with psoriasis, compared with the control group, few intercellular contacts of neutrophils with platelets were revealed. Low values of platelet-neutrophil aggregates with 3, 4, and 5 lobes in the nucleus were observed. The formation of aggregates statistically significantly correlated with the expression of LFA-1 and PECAM-1 adhesion molecules by mature neutrophils.
Conclusion. Low rates of intercellular interaction of platelets with three-, four-, and five-lobed neutrophils in psoriasis were indicative of their augmented migration from the peripheral blood to the epidermis. The adhesion molecules LFA-1 and PECAM-1 play a key role in the migration of platelet-neutrophil aggregates.
Effect of liraglutide dose on efficacy of correcting microcirculatory disorders in absolute insulin deficiency of albino rats
Authors: Lagutina Daria D. , Stepanova Tatyana V. , Savkina Angelina A. , Ivanov Alexey N.
Published: June 2022

The objective was to study the dose-dependent effects of glucagon-like peptide-1 receptor agonist, liraglutide, on microcirculation in white rats under the alloxan-induced insulin deficiency.
Materials and Methods. Our study was carried out on 70 white rats, divided into four groups: 20 intact control animals; 20 animals of the comparison group with alloxan-induced diabetes; 10 animals with insulin deficiency, injected with liraglutide at a dose of 0.2 mg/kg per day (treatment group No. 1); and 20 animals with insulin deficiency treated with liraglutide at a dose of 0.4 mg/kg per day (treatment group No. 2). Diabetic status, skin perfusion of the posterior limb and mechanisms of blood flow modulation were assessed in all groups of animals.
Results. It was established that administering liraglutide at a dose of 0.4 mg/kg per day allowed achieving complete normalization of carbohydrate metabolism in rats with alloxan-induced insulin deficiency, thereby more effectively improving the state of microcirculation, compared with a dose of 0.2 mg/kg per day.
Conclusion. The efficacy of correcting the microcirculatory disorders with liraglutide correlates with correcting the carbohydrate metabolism in rats with insulin deficiency and depends on liraglutide dose. The dose-dependent effect is achieved by the endothelial mechanism of flow modulation in microcirculation. However, the restoration of the vascular tone neurogenic component is independent of liraglutide dose.
Comparative efficiency of various molecular genetic methods in diagnosing tuberculosis
Authors: Salina Tatyana Yu. , Morozova Tatyana I.
Published: June 2022

Objective – to compare the efficacy of various molecular genetic methods for diagnosing tuberculosis and determining drug susceptibility to rifampicin (RIF).
Materials and Methods. We conducted a retrospective study of the sputum analysis results on 1,992 patients with pulmonary tuberculosis treated at Saratov Oblast Clinical Tuberculosis (TB) Dispensary from 2014 through 2018. The following methods were used: real-time polymerase chain reaction (PCR), biological microarrays, automated Xpert® MTB/RIF technology. Statistical processing of the research results was carried out using the Bayes formula based on contingency tables (four-field table) and the χ2 test. When evaluating the significance of differences between relative values, we employed the critical significance level of 0.05.
Results. In terms of etiological diagnosis of TB, higher diagnostic sensitivities of the real-time PCR and biological microarray methods (73.9% and 70.3%, correspondingly) were established, as compared with the Xpert® MTB/RIF method (34.2%) (p<0.001). The sensitivity of all methods depended on the massiveness of bacterial excretion and clinical form of TB.
Conclusions: The Xpert MTB/RIF method exhibited lower diagnostic sensitivity in verifying the diagnosis of TB, whereas its operational characteristics in terms of determining RIF-resistance were sufficiently high (sensitivity at 89.7%, specificity at 89.1%, and efficacy at 89.4%), which was comparable with the characteristics of biological microarray method (93.9%, 71.8%, 82.9%; p=0.127, p<0.001, p=0.139, respectively).
Open-heart surgery in elderly patients: short-term vs. long-term effects
Authors: Khazov Pavel A. , Maystrenko Alexey D. , Gurschenkov Alexander V. , Shvarts Elena Yu.
Published: June 2022

The objective of the study was to analyze in-hospital mortality and long-term survival of elderly patients who underwent open-heart surgery and met the criterion of frailty.
Materials and Methods. The study involved 266 patients over 75 years old complying with the frailty criterion (F-index ≤5). A total of 155 operations of coronary artery bypass grafting (CABG), 47 surgeries of aortic valve replacement (AVR), and 64 procedures of CABG in combination with AVR were performed. Study subjects were distributed among the groups depending on the surgery type. Postoperative complications were evaluated, and short-term and long-term outcomes were compared.
Results. In-hospital mortality was 5.3% in general group, 9.4% in CABG+AVR group, 3.9% in CABG group, and 4.2% in AVR group. There was no significant difference among the rates of in-hospital mortality between the groups (р>0.05). Long-term survival rates in general group were as follows: 98.3% for 1-year survival, 94.6% for 3-year survival, and 82.1% for 5-year survival. Type of surgery had no significant impact on the outcome (р>0.05).
Conclusion. Short- and long-term effects of CABG, AVR, and combination of CABG with AVR in the group of elderly patients who meet the criterion of frailty were characterized by low mortality and low incidence of non-fatal complications. The type of cardiac surgery and old age did not affect significantly the outcome of a surgical treatment.
Four Conditions for Recognition of Traditional Society in the Constitution and State Revenue Income
Authors: Adnyani Ni Ketut Sari , Atmaja Gede Marhaendra Wija , Sudantra I Ketut
Published: June 2022

This article is an interpretation of Article 18B paragraph (2) of the Indonesian constitution: four requirements for recognition of traditional societies. Using sustainable tourism development as a case study, explores the important contribution of genealogical territorial participation and the limits of recognition of the role of the State in providing legal protection and traditional societies as the main coders of legal pluralism. This exploration reveals four different conditions: conditions for survival, dynamic conditions, conditions in accordance with the principle of integration, and regulated by law. The fact that these conditions are so intricately interwoven poses unique challenges for academics and legal practitioners, but also provides a potential blueprint for constitutions and state revenues.
The Right to Nationality and Repatriation under International Law: A Study on Biharis in Bangladesh
Authors: Islam Mohammed Tahmidul , Mia Md. Tuhin , Islam Mazharul
Published: June 2022

This article aims to examine the legal position of Biharis in Bangladesh and their status in international law. It also reiterates the position of the international community, repatriation rights and judicial decisions on Bihari issues. Despite giving the citizenship rights to the Biharies in Bangladesh many of them did not renounce their Pakistani citizenship and actively refused to integrate with majority Bengalis. Therefore, the Bihari people’s right to get into Pakistan, their homeland, is an internationally recognized right having the force of customary international law. The article is based on secondary data materials. The key sources of this article include textbooks, journal articles, daily newspapers and online documents. The study has also relied on international instruments and decided cases of Apex Court of Bangladesh and Pakistan. The article found that Pakistan has violated and continues to violate the Biharis international right to get into their state of nationality by refusing repatriation. Besides, the new generations of stranded Biharis have mostly rejected their forefather’s stances and ideologies. Hence, the government should give them full opportunity to educate themselves to become productive citizens of Bangladesh.
Reform Regulation of Novum in Criminal Judges in an Effort to Provide Legal Certainty
Authors: Saputra Rian , Ardi Muhammad Khalif , Pujiyono Pujiyono , Firdaus Sunny Ummul
Published: June 2022

The research stems from Decision Number 224 PK/PID.SUS/2018 which grants the application for judicial review (hereinafter abbreviated as PK) by a suspected narcotics abuser with a novum (new evidence) in the form of previous judges' decisions. In this case, this study aims to conceptualize how the regulation of PK legal remedies in criminal cases should be. This research is a normative legal research, the approach used is a case approach, a comparative approach, and a conceptual approach, with a literature study research technique. After knowing the arguments for the admissibility of submitting a PK in the form of a District Court Decision, the author makes several comparisons with the Criminal Procedure Code (America and France), and concludes based on this comparison that the use of the basis for submitting a PK should be regulated clearly and firmly in the Criminal Procedure Code, because the two countries in its criminal procedural law it expressly states that the submission of a PK must be based on new facts and evidence which, if presented at the previous trial, has the potential to reduce or even abort the prosecution's charge
Health-related quality of life following FDG-PET/CT for cytological indeterminate thyroid nodules
Authors: de Koster Elizabeth J , Husson Olga , van Dam Eveline W C M , Mijnhout G Sophie , Netea-Maier Romana T , Oyen Wim J G , Snel Marieke , de Geus-Oei Lioe-Fee , Vriens Dennis , _ _
Published: June 2022

Objective

This study assessed the health-related quality of life (HRQoL) in patients undergoing 2-[18F]fluoro-2-deoxy-D-glucose (FDG)-PET/CT for an indeterminate (Bethesda III/IV) thyroid nodule. FDG-PET/CT accurately rules out malignancy and prevents 40% of futile diagnostic surgeries in these nodules.

Design

Secondary analyses of HRQoL data from a randomised controlled multicentre trial (NCT02208544) in 126 patients from 15 hospitals in the Netherlands were done.

Methods

Longitudinal HRQoL assessment was performed using the EuroQol 5-dimension 5-level (EQ-5D-5L), the RAND 36-item Health Survey v2.0 (RAND-36), and the Thyroid Patient-Reported Outcome (ThyPRO) questionnaire on baseline, 3, 6, and 12 months, relative to the date of the FDG-PET/CT scan.

Results

Patients who were randomised to active surveillance following an FDG-negative nodule instead of diagnostic surgery reported stable HRQoL scores throughout the year. Univariate analysis indicated better HRQoL for patients undergoing surveillance than surgical patients with benign histopathology on multiple physical and psychosocial domains. Univariate within-group analysis suggested both temporary and continued HRQoL deteriorations in patients with benign histopathology over time. Multivariate within-group analysis demonstrated no significant longitudinal HRQoL changes in patients undergoing active surveillance. In contrast, in patients with benign histopathology, worse HRQoL was observed with regard to ThyPRO cognitive impairment (P = 0.01) and cosmetic complaints (P = 0.02), whereas goitre symptoms (P < 0.001) and anxiety (P = 0.04) improved over time. In patients with malignant histopathology, anxiety also decreased (P = 0.05).

Conclusions

The reassurance of a negative FDG-PET/CT resulted in sustained HRQoL throughout the first year of active surveillance. Diagnostic surgery for a nodule with benign histopathology resulted in more cognitive impairment and physical problems including cosmetic complaints, but improved goitre symptoms and anxiety. Anxiety was also reduced in patients with malignant histopathology.
An altered state of consciousness while using anticoagulants and the incidental discovery of a pituitary lesion: considering pituitary apoplexy
Authors: Viola N , Urbani C , Cosottini M , Abruzzese A , Manetti L , Cosentino G , Marconcini G , Marcocci C , Bogazzi F , Lupi I
Published: June 2022

Pituitary apoplexy (PA) is a medical emergency with complex diagnosis and management. In this study, we describe a case of PA in a 63-year-old male treated with oral anticoagulant therapy for atrial fibrillation. In the patient, PA manifested itself with asthenia and severe headache not responsive to common analgesics. Despite the finding of a pituitary mass through CT, and in anticipation of the endocrinological evaluation and pituitary MRI, the patient’s clinical condition worsened with an escalation of headache and asthenia associated with deterioration of the visual field and impairment of consciousness level. The emergency assessments revealed an adrenal failure, whereas MRI showed a haemorrhagic pituitary macroadenoma with compression of the optic chiasm. Intravenous fluids repletion and high-dose hydrocortisone were started with a rapid improvement of the patient’s health and visual field abnormalities. Hydrocortisone was gradually reduced to a replacement dose. During the follow-up, panhypopituitarism was documented, and replacement therapies with l-thyroxine and testosterone were introduced. Three months later, a pituitary MRI showed a 50% reduction in the pituitary adenoma volume.

Learning points

Pituitary apoplexy (PA) is a medical emergency that can result in haemodynamic instability and abnormalities in the level of consciousness.

The management of PA requires a multidisciplinary team that includes endocrinologists, ophthalmologists, neuro-radiologists, and neuro-surgeons.

Pituitary MRI with gadolinium is the diagnostic gold standard for PA.

PA therapy aims to improve general conditions and treat compression symptoms, especially visual field abnormalities.

Adrenocorticotrophic hormone deficiency is a common and severe complication of PA. Thus, all patients with PA must be promptly treated with injective synthetic glucocorticoids (e.g. hydrocortisone 100 mg) and i.v. saline.

PA must be taken into consideration in case of sudden headache in patients with a pituitary macroadenoma, especially if other risk factors are recognized.
La Ayuda Oficial para el Desarrollo de España con Palestina desde el inicio del proceso de Oslo: ¿una apuesta por la construcción de paz liberal?
Authors: López Arias Lucía , Checa Hidalgo Diego
Published: June 2022

Este artículo explora la cooperación para el desarrollo de España con Palestina desde los inicios de la década de 1990 hasta 2019, dada la importante relevancia que ha tenido esta región para la política exterior española durante ese periodo. Para ello, en la investigación se ha realizado un exhaustivo análisis de las bases de datos de la cooperación española que ofrece la AECID a través de su portal web Info@OD y de numerosas fuentes documentales primarias procedentes de organizaciones del ámbito de la cooperación, tanto gubernamentales como no gubernamentales. De esta forma, se han definido las principales características de la cooperación española hacia la región y se muestra la evolución de la Ayuda Oficial para el Desarrollo del Estado español con Palestina, tanto en volumen como en modalidad de ayuda y sectores de la cooperación destacados, examinando sus continuidades y discontinuidades a través de las distintas legislaturas de Gobierno. Finalmente, el artículo destaca la utilización de las herramientas de ayuda para la aplicación de políticas de construcción de paz liberal en Palestina e Israel.
Novel Technologies as Potential Catalyst for Democratizing Urban Heritage Preservation Practices: The Case of 3D Scanning and AI
Authors: Laužikas Rimvydas , Žižiūnas Tadas , Fomin Vladislav
Published: June 2022

The conflict between heritage protection and urban infrastructure development rationales creates a context for inclusion, participation and dialogue of different heritage-related communities. However, developed in the pre-computer age of administrative practice, are often incapable, partially or completely, to accommodate the ‘new-era’ community oriented participatory practices. In this article, authors discuss the mutual effects of IT in the process of democratization of urban heritage preservation. The authors create and argue the conceptual model of distributed ledger technologies (DLT) in participatory UHP. The model demonstrates how technologies can become catalysts for democratization in situations when the regulatory and administrative change (on its own) is too inert. The article hypothesizes that novel technological developments which aim at or have the potential for increasing community involvement and democratization of administrative practice, exert their effects directly through technology-based participatory practices.
Pre-iRNR splaisingo ir jį reguliuojančių veiksnių hipoksinėje ląstelių mikroaplinkoje tyrimai
Authors:   , Vilys Laurynas
Published: June 2022

Investigating pre-mRNA splicing and its regulatory factors in a hypoxic cell microenvironment
Guidelines for food safety, health operations and production
Authors: Aboul anean Hosam El din
Published: June 2022

The aim of this study review article was to pay attention to the guidelines for food safety, health affairs operations and production in order to produce safe healthy food free of contaminants that cause bacterial and virus pathogenic poisoning and direct infection to humans. Producing a food product with special specifications for functional foods, staying away from foods that are likely to cause contamination and food poisoning, conducting chemical and microbial analyzes and food contaminants, as well as taking samples from every manufacturing step in the factory to identify critical control points to solve all problems related to the safety of the food product.
A Study on the new business strategies for the Indian apparel industry post-covid-19 pandemic
Authors: Tarai Santosh Kumar , Soundarya M
Published: June 2022

The covid-19 pandemic has disrupted enormous businesses across the globe to an extent none had ever imagined. There is no doubt about the slowdown of various businesses; however, covid was a boon to a few industries worldwide. The textile and apparel industry is one such industry where the covid-19 pandemic is both a boon and a bane. Many of these industries got shut down during the pandemic, but few managed to survive and grow during and after the post-covid-19 pandemic. The Indian apparel industry was also a victim of the pandemic, but not for a prolonged time. Few industries tried ways to overcome the struggle and successfully devised new strategies that kept them forward through the years. Thus, to understand and implement the new strategies, it is essential to get past the scenario that led to the formation of these strategies. Objective: This study highlights the scenario of the Indian apparel industry Post- Multifibre Agreement (MFA) regime that led to its success along with the existing challenges and conditions at that time, which helped in formulating the strategies followed before the covid disruption. Insights from the past studies would help in understanding and implementing the new strategies that would fit aptly in this new post covid period. The study is mostly based on data gathered from secondary sources and industry inputs from various export firms at the management level.
Alternative for tibial fixation in Patellar Tendon ACL Reconstruction
Authors: Mainine Sergio , Amorim Filipe Leal , de Queiroz Henrique VR , Arana Meira Rodrigo
Published: June 2022

Objective: Introduce an alternative for tibial fixation in Anterior Cruciate Ligament (ACL) with Patellar Tendon, in cases with long graft and a bone plug that stay outside the tibial tunnel and evaluate its results. Methods: From 2010 to 2020, 12 patients were submitted to a ACL reconstruction with a Bone-Patellar Tendon-Bone (BTB) graft using the anatomic technique. Starting with the femoral fixation, if the BTB graft is too long where the bone plug is outside the tibial tunnel, instead of cutting the graft, a cavity is dig in the tibia, distal to the tunnel entrance, and the bone plug is kept inside using a bone clip, followed by an interference screw in the tibial tunnel. With a minimum follow-up of 24 months, the patients knee stability was evaluated pre and post operatively. Results: The mean follow up was 29 months. All patients had a stable knee post operatively, with no complications. Conclusion: The ACL reconstruction using the proposed technique shown excellent results in short and long term, regarding knee stability. We believe that the proposed method is better than just cutting out the bone plug.
https://medcraveonline.com/MOJOR/soccer-first-aid-basics--review.html
Authors: Juliano Eustaquio José Martins , Renaud de Oliveira Maria Luiza , Rodrigues Carneiro Ana Gabriela , Neto Octávio Barbosa
Published: June 2022

Soccer is one of the most popular sports around the world. The large number of practitioners, associated with technical and tactical characteristics, make it subject to a large number of injuries. Therefore, it is necessary the continuous training of health professionals who act as rescuers in soccer matches. In addition, due to a series of factors, there is currently an increase in the number of potentially more serious injuries, especially concussions. This has caused concern not only for health professionals, but also for the institutions that regulate the practice of sport. In professional soccer, there is a minimum requirement of material and human resources that guarantee greater safety for competitors, something not observed in amateur. The dissemination of basic first aid knowledge is extremely relevant and should cover the entire public involved in the sport.
Management of tibial plateau fractures with special reference to column classification
Authors: Dhakshanamoorthy Raghul , Siddiqui Yasir S , Abbas Mazhar , Faizan Mohd , M Julfiqar , Khan MJ
Published: June 2022

Objective of the paper is to evaluate the outcome of the management of tibial plateau fractures with reference to Luo’s three column classification concept. The selection of surgical approach and appropriate fixation construct was dictated by the number of distinct articular fragments on CT scans and the concomitant soft tissue injury. The primary outcome measure was to evaluate the relationship between the number of column involved and fixation construct on secondary loss of reduction at healing. Secondary loss of reduction was defined as a change of alignment of ≥ 5 degrees into either varus or valgus at union. The secondary outcome measures were delayed union, non-union, peri-implant fracture and infection rates. Functional outcome were evaluated using Knee Society Score. Forty-six patients were available for final follow up. Immediate postoperative mal-alignment was noted in 5 patients. For our primary outcome measure, we have one patient with secondary loss of reduction at final follow-up in double plating group. Secondary outcome measures showed non-union in 1 (2.17%), delayed union in 3 (6.52%), superficial infection in 3 (6.52%) and deep infection in 1 patient (2.17%). No peri-implant fracture was seen. The mean time for bone healing and full-weight bearing walk was 14.5 weeks. The mean range of motion of the affected knees was 2.39 to 131.27 at final follow-up of 12 months. In sight of the findings of our study along with existing literature Luo’s three column classification is an ideal classification in managing tibial plateau fractures as it dictates the appropriate fixation construct based on the number articular fragments. However it does not take into account the integrity of soft tissues, which is almost universal association with high velocity complex tibial plateau fractures. Hence, repercussions of use of fixation construct with multiple plates will unfold in future with long follow-up comparative studies addressing the bony as well as soft tissue complications.
Abdominal pain and appendicitis in children during the COVID-19 pandemic – do we need to be especially careful?
Authors: Bašković Marko
Published: June 2022

COVID-19 (coronavirus disease 2019) in children is relatively mild, so it is easy to make a misdiagnosis in the early stages if it presents only with respiratory symptoms. At the time of the pandemic, testing for SARS-CoV-2 is important in all paediatric patients who have fever and acute abdominal pain with diarrhoea or vomiting, to differentiate acute COVID-19 or possible multisystem inflammatory syndrome in children (MIS-C) from acute appendicitis, and thus avoiding unnecessary surgery. On the other hand, early accurate diagnosis and consequent appropriate surgical and antibiotic treatment of appendicitis are important because they can prevent complications such as abscess formation and other postoperative complications. Delayed diagnosis can lead to significant morbidity that can outweigh the damage caused by COVID-19 alone. The fact that at the time of the COVID-19 pandemic radiological examination also has its limitations and can very often show a false-positive finding in children with MIS-C must also be taken into account. It is very important that paediatric surgeons are aware of the gastrointestinal manifestations of acute COVID-19 or MIS-C, and are able to distinguish this new entity from the surgical pathologies it often mimics.
Polymorphous light eruption in children – clinical presentation, differential diagnosis and treatment
Authors:   Department of Dermatology, Medical University of Warsaw, Poland. Head of the Department: Professor Lidia Rudnicka, MD, PhD, Sankowska Małgorzata , Janicka Justyna ,   Department of Dermatology, Medical University of Warsaw, Poland. Head of the Department: Professor Lidia Rudnicka, MD, PhD, Misiak-Gałązka Magdalena ,   Department of Dermatology, Medical University of Warsaw, Poland. Head of the Department: Professor Lidia Rudnicka, MD, PhD, Rudnicka Lidia
Published: June 2022

Polymorphous light eruption is classified as an immune-mediated photodermatosis. It is the most common cause of photosensitivity in children between 6 and 14 years old. It is characterised by pruritic or tingling erythematous papular or plaque lesions of sunlight-exposed skin which occur in spring or early summer. The first signs of polymorphous light eruption typically appear several hours to days after the first exposure to intense sunlight and take the form of an irritable rash persisting for a few days, and subsiding within a week or two with minimal or no scarring. Its recurrences may have a detrimental impact on the quality of life. Due to the significant heterogeneity of clinical manifestations of polymorphous light eruption, the disorder is relatively challenging to diagnose. The differential diagnoses include photosensitivity associated with lupus erythematosus, solar urticaria, actinic prurigo, erythema multiforme, photocontact allergic dermatitis, and genetic dermatoses. UVA and UVB phototesting followed by histological examination is an important diagnostic tool to objectify light-related symptoms. Once the diagnosis is established, the patient should be monitored and educated on prevention. The management of polymorphous light eruption is based on prevention such as sun protection and sunscreens. The first-line treatment includes glucocorticoids and antihistamines.
Saliva and its value as a diagnostic material
Authors:   Doctoral School, Department of Descriptive and Topographic Anatomy, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Zabrze, Poland, Potempa-Jeziorowska Magdalena , Jonczyk Paweł ,   Doctoral School, Department of Descriptive and Topographic Anatomy, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Zabrze, Poland, Świętochowska Elżbieta ,   Department of Medical and Molecular Biology, Faculty of Medical Sciences, Silesian Medical University in Katowice, Zabrze, Poland, Kucharzewski Marek
Published: June 2022

In recent years, because of huge advances in medicine and technological progress, coupled with the application of increasingly accurate diagnostic tests, the use of saliva for medical purposes has become increasingly important. Saliva is a natural digestive secretion of the major and minor salivary glands that ensures, among other things, the proper functioning of the occlusion system. Other functions include the protection of dental surfaces from various external influences, and involvement in the formation of the food bolus and in the acts of swallowing, digestion, and speech. The composition of saliva is varied. In addition to water, which is found in saliva in far greater quantities than in any other substance, it also contains various substances which are also present in the blood. Their determination in saliva often has a great diagnostic potential in the early detection of both oral and systemic diseases. The diagnosis of selected systemic diseases using saliva is becoming the subject of a growing number of scientific studies. In this paper, the authors have focused on providing the reader with basic information about the physiology of saliva and on presenting the possibilities for its diagnostic application in selected systemic diseases.
Sepsis and Streptococcus agalactiae meningitis in a 3-month-old boy
Authors:   Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine, Warsaw, Poland, Będzichowska Agata , Piotrowska-Lis Karolina ,   Paediatric Student Research Group at the Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine, Warsaw, Poland, Rychcik Paulina ,   Paediatric Student Research Group at the Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine, Warsaw, Poland, Kalicki Bolesław ,   Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine, Warsaw, Poland, Rustecka Agnieszka ,   Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine, Warsaw, Poland, Tomaszewska Agata ,   Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine, Warsaw, Poland
Published: June 2022

Streptococcus agalactiae bacteria are a common cause of neonatal sepsis and meningitis. Universal screening of pregnant women for carriage and intrapartum antibiotic prophylaxis has significantly reduced the disease prevalence in children up to 7 days of age. However, it is to be remembered that group B streptococcal infection can also affect older children, even if their mothers have tested negative for Streptococcus agalactiae during pregnancy or underwent complete perinatal antibiotic prophylaxis. This paper presents a clinical case of a 3-month-old boy treated for sepsis and Streptococcus agalactiae meningitis. The baby was born on time, with normal body weight. The infection occurred despite full maternal ampicillin perinatal therapy in the mother.
Varicella with secondary skin bacterial complications: case reports
Authors:   Department of Paediatric Infectious Diseases, National Pirogov Memorial Medical University, Vinnytsia, Ukraine, Levytska Lidiia , Nezgoda Iryna ,   Department of Paediatric Infectious Diseases, National Pirogov Memorial Medical University, Vinnytsia, Ukraine
Published: June 2022

Chickenpox is a very contagious childhood disease with a self-limited course. It is most common in children up to 10 years old, but can infect a person at any age. Varicella presents with itchy pseudo-polymorphic rash (macula, papula, vesicle, crust) and mild intoxication syndrome. The disease is benign and uncomplicated in general, but complications can occur regardless of immune status and concomitant diseases. Neurological and respiratory are among the most common complications. In the patients described in this article, we can observe secondary bacterial superinfection (pyoderma and phlegmon). These are the third most common complications of varicella, and may have serious consequences. These cases are presented to call attention to proper skincare in a patient with chickenpox and to the choice of an appropriate antipyretic to control fever. It is also important to emphasise the importance of vaccination against this disease and to combat the misconceptions of anti-vaxxers.
Comparative study of performances of UHPLC-MS/MS and HPLC/UV methods for analysis of ziprasidone and its main impurities
Authors: Čarapić Marija , Marković Bojan , Pavlovic Milena , Agbaba Danica , Nikolic Katarina
Published: June 2022

Ziprasidone is the second generation antipsychotic drug with unique multipotent G-protein-coupled (GPCR) receptor binding profile. Since ziprasidone is a highly lipophilic and unstable compound, development of efficient method for a concurrent assay of ziprasidone and its main impurities was a very challenging task.

The UHPLC-MS/MS method that we developed for simultaneous determination of ziprasidone and its main impurities (BITP, Chloroethyl-chloroindolinone, Zip-oxide, Zip-dimer, and Zip-BIT) was compared with some other related HPLC-UV methods of our own and other authorship. An increase of the mobile phase pH value from 2.5 to 4.7 units in the examined analytical methods influenced elution order of the investigated compounds. It was found out that the UHPLC-MS/MS method is more selective and sensitive than the earlier developed HPLC-UV method. Similar to our earlier HPLC-UV method, the UHPLC-MS/MS method is linear with a correlation coefficient (r) above 0.99 for all the analysed compounds, but with a negligibly lower precision and accuracy. Finally, with shorter analysis time, smaller column size and reduction of solvent consumption, UHPLC-MS/MS is assumed as a greener method than HPLC-UV for the ziprasidone purity assay.

After transfer of the UHPLC-MS/MS method to the UHPLC-DAD system, suitability of the UHPLC-DAD method for routine control of ziprasidone and its main impurities is examined and confirmed based on the retained good selectivity, resolution and short analysis time.
The Old Believers` Village Klimoutsi (Austria) in the Russian History
Authors: Svetlana Inikova
Published: June 2022

The article is devoted to the study of two historical events which took place in the Old Believers village of Klimoutsy in the Austrian Bukovina in the 1870s-1880s. This is the movement of the Bespopovtsy - Pomortsy for returning to Russia and joining them to the Orthodox Church on the rights of the Edinoverie. The problem of returning to the historical homeland is always relevant and timeless; its study provides invaluable and always in-demand historical experience. The article clarifies the causes of the movement for re-emigration among the Bespopovtsy, the conditions of resettlement put forward by them and the counter conditions of their reception and settlement in Russia put forward by the Russian government; the attitude of officials of various departments and primarily of the Russian consul in Bukovina to this problem. Movement for the transition to the Edinoverie developed in parallel among the Bespopovtsy was a unique phenomenon for foreign Old Believers. The article explores all its stages: from its origin to the creation of the Edinoverie's parish in Klimoutsy and further – its fate in the XX - early XXI century, the role of the missionary Paul of Prussia. The work is written mainly on archival documents extracted from the Russian State Historical Archive and the Archive of the Foreign Policy of the Russian Empire. In addition, the field material collected by the author in the village of Klimoutsy (Romania) in 2017 has been involved. Due to the absence of the Bespopovtsy’s political demands and their willingness to join the Orthodox Church on the rights of the same faith the conflict between this group of Old Believers and the Russian state was removed, and with it, all obstacles on the way of migrants to their homeland were liquidated. The author sees the reasons for the failure which resulted in the re-emigration in the unjustified delay in the process of discussion and decision-making by Russian officials, and in the fact that the conditions for the resettlement of Bespopovtsy to Russia approved by the Committee of Ministers did not meet the expectations of the settlers.
Interpretation of Canons in the Discourse of Marginal Orthodoxy
Authors: Andrey Sychev
Published: June 2022

Characteristics of the interpretation of the concept of "canon" in the marginal Orthodox discourse have been considered in the article. Marginal Orthodoxy is understood by the author as a set of ideas and practices characteristic of non-institutionalized movements and groups declaring their orthodoxy and accusing representatives of official Orthodoxy for the departure from tradition. The relevance of the study is stipulated by the need to establish an intra-confessional dialogue in a situation of increasing heterogeneity of Orthodoxy in Russia. The purpose of the article is to determine the role of the canons in the construction of the discourse of marginal Orthodoxy. To attain it the author reveals the features of marginal Orthodoxy discourse; compares the cases of appeal to canons in marginal and official discourses; outlines the specifics of understanding the canons in marginal Orthodoxy. The novelty of the work is conditioned by the examination of the religious space of modern Orthodoxy through the concepts of center and periphery and their relationship. Due to the insufficient theoretical development of the problem, the most resonant texts of its representatives of the first two decades of the 21st century (open letters, recordings of sermons, interviews, video speeches, journalistic articles, etc) served as the basic material for researching the discourse of marginal Orthodoxy. The official and marginal versions of Orthodoxy are considered in the article as competing discursive modes of truth production. Within the framework of the hermeneutic method, using content, discourse, and comparative analysis, the main characteristics of the discourse of marginal Orthodoxy are revealed. It is shown that the texts of marginal Orthodoxy appeal to the canons so often that in fact the entire discourse can be considered as a set of statements about the canonicity or non-canonicity of certain theories, actions and practices. The results of the study show that in marginal discourse the canon is interpreted as non-historical dogma and unconditional prohibition, which allows using it for discrediting official Orthodoxy and mobilizing supporters. The myth-making and ideological grounds of the appeal to the canons are revealed. It is proved that the concept of "canon" is organizing for the discourse of marginal Orthodoxy and without a detailed analysis of its use it is impossible to understand the specifics of this discourse.
Private and Public Islam: Social Behaviour of Indonesian Muslim in Facing Covid-19
Authors: Halim Abdul
Published: June 2022

This article reports on a library research regarding the behaviour changes of Indonesian muslim resulted from the Covid 19 pandemic. Using Henri Lefebvre's theory of public space, this study has found that, first, the changing of social-diversity that creates a new space dimension, it is the private space; second, the behaviour of social-diversity in private space showed the pattern of Islamic hyper-locality which is a form of Islam Locality with its different attribute and character; third, Islamic hyper-locality leads any confrontation of muslim groups who want to beg the public space and its religious activities; forth, the distortion of the value of Universal Islam and uncapability in facing the global war.
Etnografi Virtual Perilaku Impulsive Buying Remaja Muslimah Penggemar K-Pop di Surabaya
Authors: Khelsea Yustika Okta , Tranggono Didiek , Claretta Dyva , Achmad Zainal Abidin
Published: June 2022

This study examines the factors that influence teenager women Muslims (muslimah) of K-Pop fans' behavior in Surabaya regarding impulsive buying, the role of Twitter in eliciting their impulsive buying behavior, and to comprehend their under­standing about the impact of impulsive buying as well. Using a virtual ethnographic approach, the findings have revealed that that impulsive buying behavior was influenced by friendship and the convenience facilities provided by Twitter related to informa­tion and promotions about K-Pop merchandise. This gave rise to a new culture of impulsive buying. However, teenager Muslim women of K-Pop fans are actually aware that impulsive buying behavior violates religious norms. Therefore, their behavior in purchasing K-Pop merchandise is based on rational choices.
Hermeneutika Pesan Dakwah dalam Kumpulan Cerpen “Dari Ave Maria ke Jalan Lain ke Roma”
Authors: Mustafirin  , Agus Riyadi
Published: June 2022

This study aims to examine the moral teachings contained in the collection of short stories (cerpen) of Idrus. By using hermeneutic analysis, this study shows that Idrus' short stories convey moral teachings regarding patriotism, nationalism, lifestyle, social criticism, and faith in Allah Swt. Specifically, these teachings encompases sincerity, fortitude fortitude where calamity is a warning and a trial from Allah swt., teachings about justice and believing in Allah as well as Muhammad is the messenger of Allah swt. Although the da'wah material conveyed through these writings was produced in accordance with the demands of the social conditions of the people at that time, namely the Japanese occupation period, it is still relevant today.