bluuebunny/crossref_metadata_2025 huggingface dataset:
Production of Enzymatic Hydrolyzates from North Shrimp Wastes
Authors: Kiseleva Marina , Tabakaeva Oksana , Kalenik Tatyana , Kiselev Artem , Tatarenko Galina
Published: December 2019

Introduction. Motor muscle of a shrimp takes about 37% of the total mass. Traditionally, muscle tissue has been used in the food industry. The rest of the shrimp, i.e. about 63%, is considered waste. The production wastes of the Northern shrimp (Pandalus Borealis) are used to obtain chitin, chitosan, biologically active substances, various feeds, and dyes. Our previous research revealed that about 8% of the muscle tissue is wasted, in spite of its high content of well-balanced valuable protein. The current research objective was to develop a biotechnology that would make it possible to produce hydrolyzate from the waste products of Pandalus borealis for further use in food production. Study objects and methods. The research featured muscle tissues of the northern shrimp (Pandalus Borealis). PanReac AppliChem pepsin was chosen for enzyme preparation. Results and discussion. A set of experiments made it possible to establish the following rational parameters: hydromodule – 1:2, period – 3 h, temperature – 45°C. These conditions ensured maximum protein accumulation in the hydrolyzate. After hydrolysis, dense and liquid fractions of the hydrolyzate were obtained. The liquid phase had the following characteristics: water – 90.87%, protein – 6.45%, lipids – 0.4%, carbohydrates – 0.23%, ash – 0.51%. The freeze-drying of the liquid part of the hydrolyzate resulted in flakes of dark orange color and a dense crumbly consistency with a rich shrimp smell and taste. The protein content in the hydrolyzate obtained after freeze-drying was 74.23 ± 3.71. The hydrolizate was rich in proteins and mineral insoluble substances, while carbohydrates and lipids were found in insignificant amounts. The ratio is typical of this type of raw material. In terms of safety, the hydrolyzate met the requirements specified in regulatory documentation. The main operations included grinding, enzymatic hydrolysis for 3 h at 45°C, centrifugation, enzymatic inactivation, and freeze-drying until residual water content fell below 10%. Conclusion. The hydrolyzate obtained from northern shrimp production wastes can be used in food technology for food fortification.
Household water treatment using adequate methods in sub-Saharan countries: evidence from 2013–2016 Demographic and Health Surveys
Authors: Geremew Abraham , Damtew Yohannes Tefera
Published: December 2019

In sub-Saharan countries, where a large number of populations depend on unsafe water, household water treatment is the recommended means to reduce diarrhea. However, the practice in the region is very low. The current study is intended to assess the households' water treatment using adequate methods, boiling, adding bleach, filtration and solar disinfection, and associated factors in the region which will be an input to design and implement intervention strategies. The Demographic and Health Survey (DHS) data conducted from 2013 to 2016 in 23 sub-Saharan countries were obtained from the DHS program and weighted using the ‘svy’ command for analysis. The households' reported use of treatment methods and associated factors were analyzed using log-binomial regression. In total, 357,979 households were included in the analysis of which 29% used unimproved water for drinking purposes. Households reportedly treating water in the region were 22% and those who used adequate treatment methods were 18%. The households' reported use of adequate treatment methods was statistically associated with household head education, owning a radio and wealth quintiles. The treatment methods' use is low in the region therefore intervention on wide-scale use should be designed and implemented.
Pathophysiology of Contrast-Induced Acute Kidney Injury (CIAKI)
Authors: Vlachopanos Georgios , Schizas Dimitrios , Hasemaki Natasha , Georgalis Argyrios
Published: December 2019

:

Contrast-induced acute kidney injury (CIAKI) is a severe complication associated with the use of iodinated contrast media (CM); a sudden but potentially reversible fall in glomerular filtration rate (GFR) typically occurring 48-72 hours after CM administration. Principal risk factors related with the presentation of CIAKI are preexisting chronic kidney disease and diabetes mellitus. Studies on CIAKI present considerable complexity because of differences in CM type and dose, controversies in definition and baseline comorbidities. Despite that, it should be noted that CIAKI poses a serious health problem because it is a very common cause of hospitalacquired AKI, linked to increased morbidity and mortality and utilizing growing healthcare resources. The pathogenesis of CIAKI is heterogeneous and, thus, is incompletely understood. Three basic mechanisms appear to simultaneously occur for CIAKI development: Renal vasoconstriction and medullary hypoxia, tubular cell toxicity and reactive oxygen species formation. The relative contribution of each one of these mechanisms is unknown but they ultimately lead to epithelial and endothelial cell apoptosis and GFR reduction. Further research is needed in order to better clarify CIAKI pathophysiology and accordingly introduce effective preventive and therapeutic strategies.
Anti-NMDA Receptor Encephalitis, Vaccination and Virus
Authors: Wang Hsiuying
Published: December 2019

Anti-N-methyl-d-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune disorder. The symptoms range from psychiatric symptoms, movement disorders, cognitive impairment, and autonomic dysfunction. Previous studies revealed that vaccination might induce this disease. A few cases were reported to be related to H1N1 vaccine, tetanus/diphtheria/pertussis and polio vaccine, and Japanese encephalitis vaccine. Although vaccination is a useful strategy to prevent infectious diseases, in a low risk, it may trigger serious neurological symptoms. In addition to anti-NMDA receptor encephalitis, other neurological diseases were reported to be associated with a number of vaccines. In this paper, the anti-NMDA receptor encephalitis cases related to a number of vaccines and other neurological symptoms that might be induced by these vaccines were reviewed. In addition, anti-NMDA receptor encephalitis cases that were induced by virus infection were also reviewed.
Neurological Disorder Drug Discovery from Gene Expression with Tensor Decomposition
Authors: Taguchi Y-h. , Turki Turki
Published: December 2019

Background:

Identifying effective candidate drug compounds in patients with neurological disorders
based on gene expression data is of great importance to the neurology field. By identifying effective candidate
drugs to a given neurological disorder, neurologists would (1) reduce the time searching for effective treatments;
and (2) gain additional useful information that leads to a better treatment outcome. Although there are many
strategies to screen drug candidate in pre-clinical stage, it is not easy to check if candidate drug compounds can
also be effective to human.

Objective:

We tried to propose a strategy to screen genes whose expression is altered in model animal
experiments to be compared with gene expressed differentially with drug treatment to human cell lines.

Methods:

Recently proposed tensor decomposition (TD) based unsupervised feature extraction (FE) is applied to
single cell (sc) RNA-seq experiments of Alzheimer’s disease model animal mouse brain.

Results:

Four hundreds and one genes are screened as those differentially expressed during A946 accumulation as
age progresses. These genes are significantly overlapped with those expressed differentially with the known drug
treatments for three independent data sets: LINCS, DrugMatrix, and GEO.

Conclusion:

Our strategy, application of TD based unsupervised FE, is useful one to screen drug candidate
compounds using scRNA-seq data set.
Role of Cdk5 in Amyloid-beta Pathology of Alzheimer’s Disease
Authors: Lu Tao-Tao , Wan Chengqun , Yang Wenming , Cai Zhiyou
Published: December 2019

Alzheimer’s Disease (AD) is a progressive neurodegenerative disease with irreversible cognitive
impairment. So far, successful treatment and prevention for this disease are deficient in spite of delaying
the progression of cognitive impairment and dementia. Cyclin dependent kinase 5 (Cdk5), a
unique member of the cyclin-dependent kinase family, is involved in AD pathogenesis and may be a
pathophysiological mediator that links the major pathological features of AD. Cdk5 dysregulation interferes
with the proteolytic processing of Amyloid-beta Protein Precursor (APP) and modulates amyloidbeta
(Aβ) by affecting three enzymes called α-, β- and γ-secretase, which are critical for the hydrolysis
of APP. Given that the accumulation and deposition of Aβ derived from APP are a common hinge point
in the numerous pathogenic hypotheses of AD, figuring out that influence of specific mechanisms of
Cdk5 on Aβ pathology will deepen our understanding of AD.
A Computational Study to Prevent HIV Invasion by Bovine LF in Mucosal-Layer via Blocking of DC-SIGN_GP120 Interaction
Authors: Banerjee Arundhati , Dasgupta Rakhi , Ray Sujay
Published: December 2019

Background:

Invasion of HIV in human occurs through DC-SIGN’s interaction via the mucosal
lining during sexual transmission. Bovine Lactoferrin (bLF) has been known to hinder this invasion
via its interaction with DC-SIGN. Hitherto, protein assays have taken place but molecular-level
studies remain unexplored.

Methodology:

The 3D structures of the three proteins were studied. After protein docking (bLF_DCSIGN
and gp120_DC-SIGN), the complexes underwent simulation. Stability parameters and binding
patterns with residues were explored.

Results and Conclusion:

ΔG values, net area for solvent accessibilities and conformational fluctuations
in DC-SIGN affirm the binding of bLF with DC-SIGN to be more spontaneous and steadier contrary
to that with gp120. Residue participation inferred more interactions to occur from bLF complex
with a greater percentage of arginine (which strengthens the interaction) while electrostatic interaction
between Lys45 (bLF) and Glu26 (DC-SIGN) strengthened the complex. Arg37 played an active role
from DC-SIGN to form the stabilizing charged-neutral H-bond, while Lys63 from bLF formed two
more such stabilizing charged-neutral H-bond with DC-SIGN. The prime binding sites in DC-SIGN;
Arg37 and Gln34 occupy helices. The binding pockets in DC-SIGN may be blocked by bLF spontaneously,
to hinder their interaction with gp120. No ionic-ionic interaction was observed from gp120_DCSIGN
complex. 88th residue, which was a predominant residue in the binding pocket was found to experience
a conformational shift from coils to sheets after interaction of DC-SIGN with bLF. This
would instigate the pharmaceutical research as non-toxic LF would be economic as a remarkable peptide
inhibitor opposing HIV.
Sexual Behavior is Enhanced by Regular, Repeated Mating from Young Adulthood to Middle Age in Female Long-Evans Rats
Authors: Guarraci Fay A. , Gonzalez Chantal M.F. , Lucero Devon , Davis Lourdes K. , Meerts Sarah H.
Published: December 2019

Background:

Aging is associated neuroendocrine changes in women. Animals can be used to
model these changes, as well as changes in reproductive behavior.

Objective:

The current study was designed to characterize mating behavior across age and assess
the effects of age and sexual history on mating behavior.

Methods:

Sexual motivation was assessed using the partner-preference test, in which a female rat is
given the choice to interact with a same-sex conspecific or a sexually-vigorous male rat, with which
she can mate.

Results:

Across repeated mating tests (2-12 months of age), female rats spent more time with the
male, displayed more solicitation behaviors, were less likely to leave the male after mounts, but visited
both stimulus animals less frequently. Comparing a separate group of age-matched, hormoneyoked
female rats mated for the first time at 12 months of age to female rats mated for the first time
at 2 months of age showed that the 12 month rats visited both stimulus animals less, were less
likely to leave the male after mounts, took longer to return to the male after mounts, and displayed
fewer solicitation behaviors than their younger counterparts. Relative to middle-aged female rats
once they were sexually experienced, 12 month naïve rats spent less time with the male, were more
likely to leave the male after mounts, and displayed fewer solicitation behaviors. Furthermore, 12
month naïve rats failed to discriminate between the stimulus animals, visiting both stimulus animals
at the same rate unlike 2 month naïve or 12 month experienced rats.

Conclusion:

Taken together, these results suggest that aging affects some measures of sexual behavior,
but most effects of age can be mitigated by regular, repeated mating.
A regularização fundiária urbana de interesse social segundo a Lei 13.465 de 2017 e a (im)possibilidade de existência de uma cidade sustentável
Authors: Machado Everson Vieira
Published: December 2019

Os grandes centros urbanos não se sustentam mais com seus espaços limitados. O crescimento das cidades sem um plano ordenado e planejado, aliado à falta de fiscalização do Poder Público aumentam os danos ao meio ambiente e ao bem estar das pessoas que nas cidades vivem e por elas circulam. Políticas Públicas foram editadas visando regularizar a situação de milhares de famílias que se aglomeram em lugares de difícil acesso, ou que tiveram suas casas construídas sobre lugares irregulares do ponto de vista do planejamento urbanístico. Porém, somente um desenvolvimento aliado a programas sustentáveis nessas cidades é que possibilitará uma moradia condizente com o respeito e preservação ao meio ambiente para as atuais e futuras gerações.
Inversão do Ônus da Prova no Direito Ambiental: o que mudou após a súmula 618 do STJ?
Authors: Koerich Guilherme
Published: December 2019

O presente estudo visa analisar como a inversão do ônus da prova é aplicada no âmbito do direito ambiental, sobretudo após a recente edição da Súmula 618 do Superior Tribunal de Justiça.Corolário do princípio da precaução, a inversão do ônus da prova é mais um instrumento para garantir a máxima proteção ao meio ambiente. No entanto, algumas questões ainda não foram respondidas e a forma de sua aplicação não é pacificada, a despeito da elaboração da referida súmula.Uma delas será tratada neste estudo: a inversão do ônus da prova nas questões envolvendo direito ambiental é automática ou depende do preenchimento dos requisitos tradicionais da hipossuficiência e verossimilhança?Para tanto, irá se discorrer sobre a origem do princípio da precaução, as lacunas deixadas pela Súmula 618 do STJ e, por fim, será realizada uma sucinta análise da aplicação da inversão do ônus da prova em outros países.
A Cláusula Penal nos Contratos de Incorporação Imobiliária
Authors: Ribeiro Pereira Silva João Gabriel
Published: December 2019

A regulamentação da resilição unilateral do contrato de compra e venda de imóveis submetido ao regime de incorporação imobiliária, realizada pela Lei nº 13.786 de 27 de Dezembro de 2018, não afasta o dever do judiciário de controlar a proporcionalidade da cláusula penal, mesmo que submetida aos limites contidos no novo diploma legal. O presente trabalho procura oferecer ferramentas para que tal controle seja feito de maneira objetiva, através da decomposição analítica dos elementos que compõem as perdas ordinariamente advindas de tal modalidade de extinção contratual e atribuindo a elas peso de 20% sobre a totalidade da cláusula penal. Objetiva-se, com isso, fornecer critérios para tomada de decisão que ofereça padrões mais claros, evitando-se subjetivismo e decisões contraditórias.
A Defensoria Pública na Garantia do Acesso à Justiça
Authors: Nunes Pires Rudolfo Rafael
Published: December 2019

Este artigo busca analisar o direito fundamental de acesso à justiça, principalmente aos indivíduos hipossuficientes, bem como o papel da Defensoria Pública como facilitadora desse acesso. Para tanto, serão analisadas as questões do acesso à justiça e como a Defensoria Pública pode atuar para garantir tal direito. Foi utilizado o método indutivo, com as técnicas do referente e da pesquisa bibliográfica.
Da Omissão Inconstitucional Parcial ao “Estado de Coisas Inconstitucional”: reflexões a partir da decisão do STF na reclamação 4.374/PE
Authors: Petermann Vânia
Published: December 2019

Sob a perspectiva do ativismo judicial dialógico – intervenção legítima do Poder Judiciário na definição de políticas públicas quando realizada em diálogo com os demais Poderes -, discute-se, neste trabalho, a figura jurisprudencial do estado de coisas constitucional. Após percorrer um itinerário do seu aparecimento como técnica decisória na Colômbia e da sua consolidação nas cortes constitucionais latino-americanas, pretende-se discutir sua possível adequação ao caso discutido na Reclamação 4.374/PE, julgada pelo Supremo Tribunal Federal em 2013 a fim de verificar a (in)adequabilidade dessa decisão frente àquela categoria jurídica. Trata-se de uma ampliação da aplicação desse conceito na jurisprudência brasileira a uma temática em que ainda não foi contemplado: a assistência social e o mínimo existencial.
Evaluating the Applications of Health Information Technologies in China During the Past 11 Years: Consecutive Survey Data Analysis
Authors: Liang Jun , Li Ying , Zhang Zhongan , Shen Dongxia , Xu Jie , Yu Gang , Dai Siqi , Ge Fangmin , Lei Jianbo
Published: December 2019

Background

To achieve universal access to medical resources, China introduced its second health care reform in 2010, with health information technologies (HIT) as an important technical support point.

Objective

This study is the first attempt to explore the unique contributions and characteristics of HIT development in Chinese hospitals from the three major aspects of hospital HIT—human resources, funding, and materials—in an all-around, multi-angled, and time-longitudinal manner, so as to serve as a reference for decision makers in China and the rest of the world when formulating HIT development strategies.

Methods

A longitudinal research method is used to analyze the results of the CHIMA Annual Survey of Hospital Information System in China carried out by a Chinese national industrial association, CHIMA, from 2007 to 2018. The development characteristics of human resources, funding, and materials of HIT in China for the past 12 years are summarized. The Bass model is used to fit and predict the popularization trend of EMR in Chinese hospitals from 2007 to 2020.

Results

From 2007 to 2018, the CHIMA Annual Survey interviewed 10,954 hospital CIOs across 32 administrative regions in Mainland China. Compared with 2007, as of 2018, in terms of human resources, the average full time equivalent (FTE) count in each hospital’s IT center is still lower than the average level of US counterparts in 2014 (9.66 FTEs vs. 34 FTEs). The proportion of CIOs with a master’s degree or above was 25.61%, showing an increase of 18.51%, among which those with computer-related backgrounds accounted for 64.75%, however, those with a medical informatics background only accounted for 3.67%. In terms of funding, the sampled hospitals’ annual HIT investment increased from ¥957,700 (US $136,874) to ¥6.376 million (US $911,261), and the average investment per bed increased from ¥4,600 (US $658) to ¥8,100 (US $1158). In terms of information system construction, as of 2018, the average EMR implementation rate of the sampled hospitals exceeded the average level of their US counterparts in 2015 and their German counterparts in 2017 (85.26% vs. 83.8% vs. 68.4%, respectively). The results of the Bass prediction model show that Chinese hospitals will likely reach an adoption rate of 91.4% by 2020 (R2=0.95).

Conclusions

In more than 10 years, based on this top-down approach, China’s medical care industry has accepted government instructions and implemented the unified model planned by administrative intervention. With only about one-fifth of the required funding, and about one-fourth of the required human resources per hospital as compared to the US HITECH project, China’s EMR coverage in 2018 exceeded the average level of its US counterparts in 2015 and German counterparts in 2017. This experience deserves further study and analysis by other countries.
Role of Botulinum toxin-A for epiphora in lacrimal drainage disorders:interventional case series (Preprint)
Authors: Prasad Madhumita , Daigavane 2nd Sachin
Published: December 2019

BACKGROUND

• Obstruction of the tear drainage system is one of the most common causes of epiphora, and surgical procedures have been the standard treatments.
• Several reports described the effects of injection of BTA in the lacrimal gland in patients with epiphora.
• However, there have been few previous studies that quantitatively assessed the effect of BTA injection.
• Transconjunctival injection of BTA in the lacrimal gland shows favourable outcomes for epiphora without permanent complications.
• Injections has consistent efficacy and duration of effect, and BTA injections can be repeated for symptomatic epiphora as an alternative to complex surgery

OBJECTIVE

• To report the outcome of botulinum toxin-A (BTA) injections in the lacrimal glands in patients with epiphora.
• To study effectivness of lacrimal gland injections of botulinum toxin A for epiphora secondary to lacrimal drainage disorders

METHODS

• This will be a prospective, interventional case series to be conducted in Acharya vinoba rural hospital, Sawangi, Wardha.
• Demographic information, previous medical history, aetiology of epiphora, clinical information needed for epiphora assessment, treatment information, outcomes, and complications will be noted.
• Each patient will undergo lacrimal system examination at presentation that included lacrimal irrigation and diagnostic probing, and dacryocystography if needed.
• INCLUSION CRITERIA- proximal canalicular obstruction, functional nasolacrimal duct obstruction (NLDO), and inoperable general condition.
• EXCLUSION CRITERIA- Hyperscretion, crocodile tears, lacrimal pump failure due to 7th nerve palsy, patient not coming for followup.
• Follow-up on 1st week, 1 month, 2 months.

• All patients included in the study will undergo one or more BTA injections in the lacrimal gland and will be followed up for 2 months. Repeated BTA injections will be given when the patient recquire another injection for recurrent epiphora.
• The severity of epiphora will be assessed with the Munk epiphora rating system and the Schirmer-1 test before injection and at 1 month and 2 months after injection.
• Under topical anaesthesia with proparacaine, after elevating the lateral portion of the upper eyelid to expose the palpebral lobe of the lacrimal gland while the patient looked down and to the nasal side, a transconjunctival injection of 2.5 units/0.05 ml of BTA using a 30-gauge needle tuberculin syringe will be administered into the bulging part of the exposed palpebral lobe.

RESULTS

EXPECTED OUTCOME
Reduction in epiphora after lacrimal gland injection of botulinum toxin will be seen in cases with functional epiphora as well as those with a physical obstruction in the lacrimal drainage pathway.

CONCLUSIONS

Reduction in epiphora after lacrimal gland injection of botulinum toxin will be seen in cases with functional epiphora as well as those with a physical obstruction in the lacrimal drainage pathway.
Embedding the Pillars of Quality in Health Information Technology Solutions Using “Integrated Patient Journey Mapping” (IPJM): Case Study (Preprint)
Authors: McCarthy Stephen , O'Raghallaigh Paidi , Woodworth Simon , Lim Yoke Yin , Kenny Louise C , Adam Frédéric
Published: December 2019

BACKGROUND

Health information technology (HIT) and associated data analytics offer significant opportunities for tackling some of the more complex challenges currently facing the health care sector. However, to deliver robust health care service improvements, it is essential that HIT solutions be designed by parallelly considering the 3 core pillars of health care quality: clinical effectiveness, patient safety, and patient experience. This requires multidisciplinary teams to design interventions that both adhere to medical protocols and achieve the tripartite goals of effectiveness, safety, and experience.

OBJECTIVE

In this paper, we present a design tool called Integrated Patient Journey Mapping (IPJM) that was developed to assist multidisciplinary teams in designing effective HIT solutions to address the 3 core pillars of health care quality. IPJM is intended to support the analysis of requirements as well as to promote empathy and the emergence of shared commitment and understanding among multidisciplinary teams.

METHODS

A 6-month, in-depth case study was conducted to derive findings on the use of IPJM during Learning to Evaluate Blood Pressure at Home (LEANBH), a connected health project that developed an HIT solution for the perinatal health context. Data were collected from over 700 hours of participant observations and 10 semistructured interviews.

RESULTS

The findings indicate that IPJM offered a constructive tool for multidisciplinary teams to work together in designing an HIT solution, through mapping the physical and emotional journey of patients for both the current service and the proposed connected health service. This allowed team members to consider the goals, tasks, constraints, and actors involved in the delivery of this journey and to capture requirements for the digital touchpoints of the connected health service.

CONCLUSIONS

Overall, IPJM facilitates the design and implementation of complex HITs that require multidisciplinary participation.

CLINICALTRIAL
Análisis del beneficio en el uso de los dispositivos móviles durante la experiencia del viajero en Tijuana, Baja California
Authors: Miranda Zavala Ana María , Cruz Estrada Isaac
Published: December 2019

El objetivo de la investigación es analizar los beneficios del uso de los dispositivos móviles en la experiencia del viajero que arriba a la ciudad de Tijuana. Mediante metodología cuantitativa, con base en 95% de confianza y 5% de error, se obtuvo una muestra de 384 encuestas aplicadas a visitantes. El instrumento consta de tres bloques: el empleo de servicios digitales en el dispositivo móvil, la frecuencia con la que se utilizan las aplicaciones instaladas y el nivel de satisfacción del viajero en el destino debido al uso de los servicios digitales. Los resultados muestran que existe una correlación media significativa de 0.01 entre la frecuencia con la que el viajero utiliza los servicios móviles y la satisfacción que proporciona la disposición de tales servicios durante su estancia. Se concluye que la tecnología se ha convertido en un componente indispensable para los turistas y que el equipo smartphone contribuye a la satisfacción de la comunicación, a la consulta de información y a la compra y movilidad del consumidor turístico.
Arrendamiento de apartamentos turísticos por internet
Authors: Amunátegui Perelló Carlos
Published: December 2019

The short-term rental of tourist apartments through the Internet is a new phenomenon in our social environment. For this purpose, the means used for its development are causing a series of consequences that complicate neighbor coexistence and, in many cases, alter the character of some traditionally residential areas. The purpose of this paper is to clarify the legal relations that are developed through such contracts, as well as to explain the defense mechanisms that neighbors have to object to said practice.
El uso de ALEPH en la Biblioteca Conjunta de Ciencias de la Tierra.
Authors: Armendáriz Sánchez Saúl , Castro Escamilla Minerva
Published: December 2019

Se ofrece un panorama general del uso del sistema aleph en la Biblioteca Conjunta de Ciencias de la Tierra de la Universidad Nacional Autónoma de México, mostrando las diversas aplicaciones en donde se ha implementado, que van desde la generación de catálogos bibliográficos hasta la conformación de bases de datos con imágenes y textos completos de apoyo directo a la investigación.Así mismo, se hace una evaluación de los resultados obtenidos hasta el momento y se presentan los recursos generados con aleph, así como el uso e impacto de las interfaces creadas por la Dirección General de Bibliotecas (dgb-unam) y aplicadas para los diferentes catálogos y bases de datos, señalando los beneficios y problemas a los que nos enfrentamos a lo largo del proyecto.
Terapia sustitutiva y su impacto en calidad de vida de pacientes con enfermedad renal crónica terminal
Authors: Martínez Gutiérrez Fernando , Roy García Ivonne Analí , Torres Rodríguez José Luis
Published: December 2019

Objetivo: evaluar el puntaje de calidad de vida (cv) de acuerdo con el tipo de tratamiento sustitutivo de función renal (tsfr) en pacientes con enfermedad renal crónica terminal. Métodos: estudio transversal analítico. Se incluyeron pacientes con tsfr, en diálisis peritoneal (dp) o hemodiálisis (hd), mayores de 18 años, sin agudización de enfermedad, adscritos al Hospital General Regional No. 1 de la Ciudad de México. Se llevó a cabo de diciembre de 2018 a marzo de 2019. La cv se midió con el índice eq-5D y la escala de evaluación análoga para obtener índice de autoevaluación de salud, las variables clínicas y sociodemográficas se tomaron de expediente clínico y mediante el interrogatorio. Resultados: se incluyó un total de 406 participantes, 203 pacientes en hemodiálisis y 203 pacientes en dp. Se encontró una media del índice eq-5D de 0.46±0.18 para dp versus 0.29±0.22 para hd (p<0.001). El índice de autoevaluación no mostró diferencia entre los grupos. Los indicadores de calidad de vida con mayor afección en los pacientes con hd fueron dolor y ansiedad o depresión. Conclusión: en pacientes con enfermedad renal crónica terminal la hd se asocia a menor calidad de vida.
Ideación suicida y su asociación con el apoyo social percibido en adolescentes
Authors: Franco Neri Blanca Ivett , Mendieta Ávila Zuleyma , Juárez Huicochea Nancy Elizabeth , Castrejón Salgado Ricardo
Published: December 2019

Objetivo: conocer la prevalencia de la ideación suicida y determinar la asociación entre la ideación suicida y el apoyo social percibido en adolescentes. Métodos: estudio transversal analítico. Se evaluaron 267 adolescentes de doce a diecisiete años de edad, ambos sexos, derechohabientes del Hospital General Regional con Medicina Familiar No.1, del Instituto Mexicano del Seguro Social (imss), en Cuernavaca, Morelos, México, que acudieron a la consulta externa de medicina familiar por cualquier motivo diferente de un trastorno mental. La obtención de la información de las principales variables de interés fue a través del cuestionario de ideación suicida de Beck y la escala de apoyo social percibido de Vaux. Se realizó un análisis descriptivo y se ajustó un modelo de regresión logística para evaluar la fuerza de asociación entre la ideación suicida y el apoyo social. Resultados: la prevalencia de ideación suicida fue de 16.48%. Se estimó una razón de momios (rm) de protección para ideación suicida rm = 0.37 (ic 95% 0.16, 0.84, p = 0.018) y 0.30 (ic 95% 0.12, 0.71, p = 0.006) del apoyo social medio y alto, respectivamente, en comparación con el apoyo social bajo. Asimismo, se observó que a mayor apoyo social percibido en los adolescentes mayor protección para ideación suicida (p de tendencia < 0.05). Conclusión: se detectó una alta prevalencia de ideación suicida y se determinó que a mayor apoyo social percibido menor ideación suicida en adolescentes. Estos hallazgos podrían ayudar a sustentar programas preventivos en el primer nivel de atención y sumarse a los esfuerzos de prevención del suicidio.
Factores de riesgo para síndrome de caídas en adultos mayores con polifarmacia
Authors: Cabrera Valenzuela Oscar , Roy García Ivonne , Toriz Saldaña Adriana
Published: December 2019

Objetivo: determinar los factores de riesgo asociados al síndrome de caídas en adultos mayores con polifarmacia. Métodos: se llevó a cabo un estudio transversal, de marzo a abril de 2019. Se incluyeron adultos mayores de 60 años que acudieron a consulta externa en la Unidad de Medicina Familiar No. 28, con prescripción y consumo mínimo de cuatro fármacos simultáneamente (polifarmacia). Para evaluar las caídas se utilizó el cuestionario de estudio de la Organización Mundial de la Salud (oms). Se evaluaron como factores de riesgo de caídas las variables: edad, sexo, estado civil, escolaridad, peso, talla, índice de masa corporal, tipo de medicamentos, comorbilidades y uso de apoyos externos al desplazarse. Para conocer las diferencias de acuerdo con la presencia de caídas se utilizó la prueba de χ2 en las variables cualitativas, para determinar los factores de riesgo para caídas se calcularon or y se realizó un modelo de regresión logística ajustado por el uso de antidepresivos, diuréticos y benzodiacepinas. Resultados: se incluyó a un total de 264 pacientes, la mediana de medicamentos consumidos fue de seis (ric 4-7), los fármacos que se prescribieron con mayor frecuencia fueron los antihipertensivos, antiinflamatorios no esteroides y diuréticos. Del total de los participantes, 79 presentaron caídas en los últimos seis meses (29.9%). Al analizar los factores de riesgo asociados a caídas en el modelo multivariado, el uso de antidepresivos mostró un or 3.14 (ic 95% 1.46-6-71) y el de diuréticos un or 1.84 (ic 95% 1.1-3.37). Conclusión: los factores de riesgo asociados a caídas en pacientes con polifarmacia fueron el consumo de antidepresivos y diuréticos.
Ictus por consumo de tóxicos inicialmente no reconocido
Authors: Vazquez Andrés David , Diaz García Antonio , Encarnación Navarro Juan Antonio , Martínez Monje Félix , Pérez Valencia Marta , Leal Hernández Mariano
Published: December 2019

El consumo excesivo de cocaína es un problema de salud pública en el mundo, dicho consumo representa un reto para los sistemas clínicos y hospitalarios debido al impacto que tiene a nivel cardiovascular en los consumidores. En el presente escrito se aborda el caso de un varón de 46 años con debilidad en el hemicuerpo izquierdo, que refiere haber consumido únicamente tabaco como sustancia tóxica; posterior al estudio clínico, pero en pruebas complementarias, se determina la presencia de vasoespasmo severo inducido por cocaína.
LA INDEPENDENCIA DE LOS BANCOS CENTRALES Y LA INFLACIÓN: UN ANÁLISIS EMPÍRICO
Authors: Chiquiar Daniel , Ibarra Raúl
Published: December 2019

En este trabajo analizamos la relación entre la independencia de los bancos centrales y la inflación en un panel de 182 países para el periodo de 1970 a 2018. Para calcular el grado de independencia se utilizan dos medidas, el índice de Garriga (2016), construido a partir de las leyes y reglamentos internos de los bancos centrales, y el índice de Dreher, Sturm y de Haan (2008), basado en la tasa de rotación de los gobernadores. Los resultados indican que una mayor independencia de los bancos centrales está asociada a menores niveles de inflación, tanto para los países de alto ingreso como para los países de bajo y medio ingreso, así como a una menor volatilidad de inflación para la muestra completa de países. Lo anterior contribuye a un mayor bienestar de la población, en la medida en que se evitan los costos asociados a una inflación alta y volátil. Los resultados son robustos al uso de las dos medidas alternativas de independencia, al uso de dos enfoques alternativos para evitar simultaneidad y a la inclusión de variables de control.

 

THE INDEPENDENCE OF CENTRAL BANKS AND INFLATION: AN EMPIRICAL ANALYSIS

ABSTRACT

This paper analyzes the relationship between central bank independence and inflation in a panel of 182 countries for the period from 1970 to 2018. To gauge the degree of independence, two measures are used, the Garriga (2016) index, constructed from the laws and internal regulations of central banks, and the Dreher, Sturm and de Haan (2008) index, based on the turnover rate of governors. The results indicate that greater central bank independence is associated with lower levels of inflation, both for high-income countries and for low and middle-income countries, as well as lower inflation volatility for the entire sample of countries. This contributes to a higher social welfare by avoiding the costs associated with high and volatile inflation. The results are robust to the use of the two alternative measures of independence, to the use of two alternative approaches to avoid simultaneity, and to the inclusion of control variables.
Influence of Types And Concentration of Natural Pesticides to Mortality of Red Mite (Panonychus citri McGregor) and Persistence of That Pesticides
Authors: Kristova Iva , Roeswitawati Dyah , Muhidin Muhidin , Endarto Otto
Published: December 2019

Tungau merah ( Panonychus citri McGregor) adalah salah satu hama tanaman yang menyerang daun jeruk. Biasanya, petani mengendalikan hama menggunakan pestisida kimia dan menyebabkan kerusakan lingkungan karena racun yang terkandung dalam bahan pestisida. Pestisida kimia juga menghasilkan peningkatan resistensi hama terhadap pestisida. Pestisida persisten juga meninggalkan residu yang sulit dibersihkan pada tanaman sehingga pestisida alami diperlukan sebagai alternatif pestisida kimia. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh konsentrasi pestisida nabati daun sirsak ( Annona muricata ), daun pepaya ( Carica papaya ), Krisanmembuat kematian hama merah dan pestisida nabati tetap ada. Hasil penelitian menunjukkan bahwa konsentrasi pestisida 5% menghasilkan 100% mortalitas fase imago dan instar fase 1 pada 48 jam pengamatan. Angka kematian tertinggi adalah perlakuan pestisida daun pepaya konsentrasi 5% pada fase imago yaitu sejumlah 29,67
Applications Various Extracts of Plant On Stem Growth Response of Red Dragon Fruit (Hylocereus polyrhizus)
Authors: Sanjaya Wiwit , Indratmi Dian , Sufianto Sufianto
Published: December 2019

This study aims to determine the response of the growth of red dragon fruit stem cuttings (Hylocereus polyrhizus) with the treatment of various plant extracts and dosage of goat manure. This research was conducted in experimental garden of UMM. This research was conducted from October 2017 until January 2018. The study used a randomized block design, which was repeated 3 times with 2 factors. Factor 1 is a kind of plant extract and factor 2 is the dosage of manure. Factor 1 consists of 4 level, while factor 2 that consists of 3 level. Observation parameters include: Shoots, shoot number, shoot length, root length, root number, total wet weight, shoot dry weight, wet root weight, and root dry weight. The results showed that the treatment of green bean sprout extract and dose 187.5 g / polybag showed the best result on the number of shoot and wet weight of cuttings. Treatment of green bean sprout extract showed relatively good results. Treatment of fertilizer doses of 187.5 g / polybag showed relatively good results.
The Global Social Enterprise Lawmaking Phenomenon: State Initiatives on Purpose, Capital, and Taxation
Authors: Liao Carol , Tawfik Elsir U. , Teichreb Pat
Published: December 2019

New laws designed to foster and govern social enterprises are propagating throughout the world. Beyond American initiatives, relatively little has been written to date on the global contagion of lawmaking to address the burgeoning field of social enterprise. Increased corporate lobbying to transplant American “benefit” corporation legislation into other countries, with little sensitivity towards existing legal ecosystems in those nations, has generated an urgency to broaden the literature and unearth the wide range of social enterprise law initiatives occurring across the globe. This article identifies over 40 state initiatives across 30 countries to distinguish this international movement. Critical thematic issues are identified from the available data, in hopes of shifting the focus away from private American interests in non-US countries and adding new knowledge to the development of social enterprise law and policies in the years ahead. This article begins by detailing various ways in which states have defined the purpose of social enterprise and social enterprise-type businesses, including how jurisdictions have experimented between state-run certifications and separate corporate legal structures to meet growing demands from particular sectors and stakeholders. We find that most jurisdictions require social enterprises to have a specific social purpose designed to serve the targeted needs of specific sectors, marginalized groups, and/or vulnerable communities. Next, we examine how new state legislation has sought to ease or restrict capital access for these social enterprises. Finally, we provide a detailed overview of various tax initiatives explored by states to promote and foster social enterprises. We suggest that lawmakers proceed with caution in the development of social enterprise laws, particularly when they are in response to private interest groups, and engage in fulsome discussions on the range of available legal methods to foster social enterprise within their jurisdictions.
Beliefs and attitudes of psychiatric outpatients toward mental disorders and antidepressants
Authors: AKINCI Erhan , BUZRUL SONMEZ Sema
Published: December 2019

Introduction: The present study aims to investigate a group of young adult psychiatric outpatients’ knowledge of and attitude toward mental disorder and antidepressants, and determine the relevant factors affecting them.Methods: The study included 81 patients attending the psychiatric outpatient clinic, diagnosed with adjustment disorders, depression and/or anxiety disorder based on DSM-5 criteria, and met the research requirements. The data were collected through an information form for sociodemographic and clinical characteristics, a form to evaluate the knowledge of and attitudes toward the use of antidepressants, and based on the Beliefs Toward Mental Illness Scale (BMI). Severity of depression and anxiety was evaluated with Beck’s Depression Inventory and Beck’s Anxiety Inventory. Results: Regarding age groups, individuals in the 26-32 age group had higher overall scores. The patients with major depression were found to have higher BMI scores. The linear regression analysis revealed that age, education, depression severity and attitudes toward antidepressants were the factors associated with the overall BMI scoresConclusions: This study suggests that some sociodemographic variables, i.e. (age and educational statue), severity of depression and attitudes toward antidepressants are likely influence the beliefs toward mental disorders. Keywords: Mental disorders, beliefs, attitudes, antidepressants
O TEMA DA SAÚDE NA FORMAÇÃO INICIAL EM EDUCAÇÃO FÍSICA EM UMA UNIVERSIDADE PÚBLICA: REFLEXIVIDADE, AGÊNCIA E ESTRUTURA
Authors: Oliveira Victor José Machado de , Gomes Ivan Marcelo
Published: December 2019

Investiga como os professores influenciam na configuração do tema da saúde nos currículos de formação em Educação Física (EF). Apresenta o recorte de uma tese de doutorado e faz opção pela análise de dados produzidos a partir dos currículos vitae dos professores do CEFD/UFES e dos concursos ofertados entre 1990 e 2017. Com enfoque na teoria da estruturação de Anthony Giddens, discute como os dados produzidos apresentam, hegemonicamente, uma biologização do currículo e como a agência do professor e a estrutura de políticas curriculares e da pós-graduação influenciam esses processos; também observa-se a emergência de perspectivas ampliadas vinculadas às Ciências Sociais/Humanas e à Saúde Coletiva. Avança da discussão “disciplinar” do currículo para dar destaque à presença do professor como elemento para a análise das políticas de formação em EF.
MEMÓRIA DO JUDÔ NA CIDADE DO RECIFE: UMA ANÁLISE A PARTIR DE SUA RELAÇÃO COM A EDUCAÇÃO E O PROCESSO CIVILIZATÓRIO
Authors: Gondim Denis Foster , Rangel de Melo Esdras Henrique , Mazzei Leandro Carlos , Kohl Henrique Gerson , Menezes Vilde Gomes
Published: December 2019

Objetiva-se analisar a história do judô recifense e suas dimensões educacionais e civilizatórias por meio da técnica de análise de conteúdo das falas de antigos senseis de judô em Recife. Constatou-se que o judô possibilita a aprendizagem, formação para a vida constituída por regras e a formação ética/moral diante da sociedade, através de fatores como disciplina e hierarquia. As entrevistas indicam os ganhos do judô como modalidade esportiva e reconhece-se que o judô esportivizado atual teve perdas. Conclui-se que, dentre as modalidades esportivas, o judô ainda se diferencia por conta de suas características e especificidades filosóficas preconizadas por Jigoro Kano e sua incidência sobre a educação.
LA ACTIVIDAD FÍSICA REPRESENTADA EN LOS LIBROS DE TEXTO DE EDUCACIÓN FÍSICA EN EDUCACIÓN PRIMARIA
Authors: Moya-Mata Irene , Ruiz-Sanchis Laura , Martín-Ruiz Julio , Ros Ros Concepción
Published: December 2019

Resumo: O objetivo deste estudo é analisar a representação da atividade física que aparece nos livros didáticos de Educação Física e sua relação com os diferentes blocos de conteúdos da área, no Ensino Fundamental. A amostra foi composta por um total de 3836 imagens publicadas em 34 livros didáticos pertencentes a seis editores espanhóis, entre 2006 e 2013. A técnica de pesquisa foi a análise de conteúdo utilizando a ferramenta SAIMEF. O software SPSS 22.0 foi utilizado para a análise estatística. Os resultados mostram uma clara predominância do bloco de conteúdo dos "jogos e atividades esportivas". Este desequilíbrio na representação dos blocos não responde aos ensinamentos mínimos que o Real Decreto 1513/2006 estabelece no currículo Primário no contexto espanhol, motivo pelo qual é necessário refletir sobre a visão tradicional da atividade física neste contexto. material curricular.Palavras-chave: Educação Física. Ensino Fundamental. Imagem corporal. Atividade Física.
TEMPOS E ESPAÇOS DE GINÁSTICA: SENTIDOS E SENSIBILIDADES QUE SE EDUCAM
Authors: Puchta Diogo Rodrigues , Taborda de Oliveira Marcus Aurelio
Published: December 2019

O artigo tem como objetivo observar prescrições sobre a definição dos espaços e dos tempos para a prática da ginástica nas escolas, no período compreendido entre as três últimas décadas do século XIX e as duas primeiras do século XX. Para a sua escrita, foram mobilizadas diferentes fontes documentais, como programas de ensino, propostas legislativas e manuais de ginástica. A partir das análises foi possível perceber que a escolarização da ginástica representou não apenas a resposta a um novo tipo de sensibilidade, mas a sua produção, como a própria definição de novos valores e costumes na viragem dos oitocentos para o início do século XX.
O CURRÍCULO DE FORMAÇÃO EM EDUCAÇÃO FÍSICA: ANÁLISE DAS PRODUÇÕES CIENTÍFICAS
Authors: Resende Moisés Sipriano , Lazzarotti Filho Ari
Published: December 2019

A pesquisa teve como objetivo investigar como as produções científicas veiculadas por periódicos no período de 2000 a 2017 têm analisado o currículo de formação em Educação Física. Foi realizada uma pesquisa do tipo bibliográfica em dez periódicos classificados no Qualis Capes de A1 a B3 em Educação Física e analisados o título, o resumo e as palavras-chave de 230 artigos. Para a análise dos dados foi empregada a análise de conteúdo. O nível de desenvolvimento curricular mais analisado foi o currículo realizado, caracterizado por conhecimentos aprendidos pelos estudantes. Nenhuma pesquisa analisou o currículo avaliado. O tema mais investigado foi “Disciplinas dos cursos”, e a maioria das pesquisas não utiliza referências para conceituar currículo. Sugere-se maior articulação entre os níveis do currículo com ênfase no currículo avaliado.