bluuebunny/crossref_metadata_2025 huggingface dataset:
Inclusion of an Optimized Plasmodium falciparum Merozoite Surface Protein 2–Based Antigen in a Trivalent, Multistage Malaria Vaccine
Authors: Eacret Jacqueline S. , Parzych Elizabeth M. , Gonzales Donna M. , Burns James M.
Published: March 2021

Plasmodium falciparum merozoite surface protein (PfMSP)2 is a target of parasite-neutralizing Abs. Inclusion of recombinant PfMSP2 (rPfMSP2) as a component of a multivalent malaria vaccine is of interest, but presents challenges. Previously, we used the highly immunogenic PfMSP8 as a carrier to enhance production and/or immunogenicity of malaria vaccine targets. In this study, we exploited the benefits of rPfMSP8 as a carrier to optimize a rPfMSP2-based subunit vaccine. rPfMSP2 and chimeric rPfMSP2/8 vaccines produced in Escherichia coli were evaluated in comparative immunogenicity studies in inbred (CB6F1/J) and outbred (CD1) mice, varying the dose and adjuvant. Immunization of mice with both rPfMSP2-based vaccines elicited high-titer anti-PfMSP2 Abs that recognized the major allelic variants of PfMSP2. Vaccine-induced T cells recognized epitopes present in both PfMSP2 and the PfMSP8 carrier. Competition assays revealed differences in Ab specificities induced by the two rPfMSP2-based vaccines, with evidence of epitope masking by rPfMSP2-associated fibrils. In contrast to aluminum hydroxide (Alum) as adjuvant, formulation of rPfMSP2 vaccines with glucopyranosyl lipid adjuvant–stable emulsion, a synthetic TLR4 agonist, elicited Th1-associated cytokines, shifting production of Abs to cytophilic IgG subclasses. The rPfMSP2/8 + glucopyranosyl lipid adjuvant–stable emulsion formulation induced significantly higher Ab titers with superior durability and capacity to opsonize P. falciparum merozoites for phagocytosis. Immunization with a trivalent vaccine including PfMSP2/8, PfMSP1/8, and the P. falciparum 25 kDa sexual stage antigen fused to PfMSP8 (Pfs25/8) induced high levels of Abs specific for epitopes in each targeted domain, with no evidence of antigenic competition. These results are highly encouraging for the addition of rPfMSP2/8 as a component of an efficacious, multivalent, multistage malaria vaccine.
What influences aromatase inhibitor continuation intention among breast cancer survivors?
Authors: Seo Young Kyung , Park Jeongok , Park Jin-Hee , Kim Sue
Published: March 2021

Purpose: Aromatase inhibitors (AIs) are widely prescribed for postmenopausal women with breast cancer and are known to cause musculoskeletal pain. This study aimed to identify factors associated with AI continuation intention among breast cancer survivors (BCS). Methods: A cross-sectional survey was conducted on 123 BCS (stages I–III), who had been taking AIs for at least 6 weeks. Participants were recruited from a cancer center in Goyang, Korea, from September to November 2019. Descriptive statistics, Welch analysis of variance, Pearson correlation coefficients, and simple linear regression were used for the analysis.Results: Belief in endocrine therapy was a significant predictor of AI continuation intention (β=.66, p<.001). The majority of participants (87.0%) reported experiencing musculoskeletal pain since taking AIs and the score for the worst pain severity within 24 hours was 5.08±2.80 out of 10. Musculoskeletal pain, however, was not associated with AI continuation intention. Fear of cancer recurrence (FCR) was clinically significant (≥13) for 74.0% of the respondents (mean, 17.62±7.14). Musculoskeletal pain severity and pain interference were significantly associated with FCR (r=.21, p<.05; r=.35, p<.01, respectively). Pain interference was significantly associated with belief in endocrine therapy (r=–.18, p<.05). Conclusion: AI continuation intention can be modified by reinforcing patients’ belief in endocrine therapy. Musculoskeletal pain may have a negative effect on belief in endocrine therapy and increase FCR among BCS. Thus, awareness of musculoskeletal pain during AI therapy should be raised and further research is required to develop multidisciplinary pain management strategies and clinical guidelines to reinforce belief in endocrine therapy.
Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma
Authors: Le Lulu , Luo Ji , Wu Haifang , Chen Ling , Tang Xiaoli , Fu Fen
Published: March 2021

Endometrial cancer (EC) is the most common gynecologic malignancy and still remains clinically challenging. We aimed to explore the potential biomarkers of EC and provide a theoretical basis for early screening and targeted therapy. The available transcriptome data from the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) were analyzed to identify differentially expressed genes. Immunohistochemistry was performed to detect gene expression. We analyzed the associations of MYBL2 with clinicopathological features and survival time and the biological effect of MYBL2 on the proliferation of EC cells. The effect of MYBL2 silencing on the transcriptome of EC cell model was analyzed by RNA-Seq. MYBL2 was significantly upregulated with obvious copy number alteration (CNA) in EC. Copy number amplification significantly increased MYBL2 mRNA expression, which led to a poor prognosis and severe pathological types of EC. Additionally, MYBL2 silencing significantly inhibited proliferation and induced apoptosis and G1-phase cell cycle arrest in EC cell lines. Our results indicate that MYBL2 is closely related to the cell cycle and apoptosis pathways in EC. The findings in this study provide evidence that MYBL2 can serve as a new candidate prognostic marker and a target for future therapeutic intervention in EC.
Collegiate Athletic Trainers' Experiences With Work-Family Conflict and Work-Family Guilt Based Upon Organizational Factors
Authors: Rynkiewicz Kelsey M. , Eason Christianne M. , Singe Stephanie M.
Published: March 2021

Context

The collegiate athletic setting has been described as having high workloads and working demands. The extensive time commitment required of athletic trainers working in this setting has been identified as a precursor to work-family conflict (WFC) and work-family guilt (WFG). Although individualized, experiences in the work-life interface can largely be affected by organizational factors (ie, elements specific to the workplace). Staff size and patient load may influence the athletic trainer's feelings of WFC and WFG, yet these factors have not been directly studied.

Objective

To examine organizational factors and experiences of WFC and WFG among collegiate athletic trainers.

Design

Cross-sectional study.

Setting

Collegiate setting.

Patients or Other Participant(s)

A total of 615 (females = 391, gender variant or nonconforming = 1, males = 222, preferred not to answer = 1) athletic trainers responded to an online survey. The average age of participants was 33 ± 9 years, and they were Board of Certification certified for 10 ± 8 years. A total of 352 participants (57.2%) worked in National Collegiate Athletic Association Division I, 99 in Division II (16.1%), and 164 in Division III (26.7%).

Main Outcome Measure(s)

Participants responded to demographic and workplace characteristic questions (organizational infrastructure, staff size, and number of varsity-level athletic teams). They completed WFC and WFG scales that have been previously validated and used in the athletic trainer population.

Results

Work-family conflict and WFG were universally experienced among our participants, with WFC scores predicting WFG scores. Participants reported more time-based conflict than strain- or behavior-based conflict. No differences in WFC and WFG scores were found among organizational infrastructures. Weak positive correlations were present between staff size and WFC scores and WFG scores. The number of athletic teams was not associated with WFC or WFG scores.

Conclusions

Organizational factors are an important component of the work-life interface. From an organizational perspective, focusing on improving work-life balance for the athletic trainer can help mitigate experiences with WFC and WFG.
Table of Contents Vol 12, No 1 (2020)
Authors: Office Editorial
Published: March 2021

No abstract available.
Table of Contents Vol 41, No 1 (2020)
Authors: Office Editorial
Published: March 2021

No abstract
Biotin-Thiamine-Responsive Basal Ganglia Disease in Children
Authors: Saini Arushi G. , Sharma Suvasini
Published: March 2021

Biotin-thiamine-responsive basal ganglia disease is a rare, autosomal recessive, treatable, neurometabolic disorder associated with biallelic pathogenic variations in the SLC19A3 gene. The condition may present as an early-childhood encephalopathy, an early-infantile lethal encephalopathy with lactic acidosis, with or without infantile spasms, or a late-onset Wernicke-like encephalopathy. The key radiological features are bilateral, symmetrical lesions in the caudate, putamen, and medial thalamus, with variable extension into the brain stem, cerebral cortex, and cerebellum. Treatment is life long and includes initiation of high dose biotin and thiamine. Genetic testing confirms the diagnosis. The prognosis depends on the time from diagnosis to the time of vitamin supplementation. The genotype-phenotype correlations are not clear yet, but the early infantile phenotype portends a poorer prognosis. We provide a brief overview of the disorder and emphasize the initiation of high-dose biotin and thiamine in infants and children with unexplained encephalopathy and basal ganglia involvement.
Treatment-Resistant Schizophrenia with High-Risk Pregnancy
Authors: Khar Prerna Balkrishen , Panse Smita , Das Nishant
Published: March 2021

Managing a severe treatment-resistant psychiatric illness in the context of pregnancy has always been a challenge for psychiatrists, especially with a comorbid medical illness. We present a case of an elderly primigravida having schizophrenia of 22 years, with high-risk pregnancy, who suffered from an acute psychotic exacerbation during pregnancy. She was managed with clozapine, aripiprazole, and amisulpiride, after a failed trial of olanzapine and electroconvulsive therapy. This case highlights the challenges in managing an elderly primigravida with comorbid gestational diabetes mellitus and fibroid who required prolonged hospitalization throughout her pregnancy. A strong liaison with an obstetrician goes a long way in ensuring smooth management.
Caries Prevalence and Associated Risk Factors in School Children at Kannur in Kerala, India
Authors: Nithya K , Peedikayil Faizal C. , Chandru T.P , Kottayi Soni , Ismail Shabnam , Aparna T.P
Published: March 2021

Background:

Caries is the most prevalent affliction of children and is dependent on various factors such as social, economic, demographic and nutritional factors.

Aim:

This study was conducted to determine the prevalence of dental caries in school going children and its association with risk factors.

Materials and Methods:

A cross-sectional study was conducted during the period from August 2019 to December 2019. Study subjects were 1947 school children. The examination was done by a single examiner and the data was entered by trained assistants. A semi-structured questionnaire was used to record the risk factors for dental caries in children. The components of Decayed, missing, filled (DMF) and Decayed, extracted, filled (def) were recorded as per the criteria of WHO (1997) for diagnosing caries. Using SPSS version 22 (IBM Corporation Chicago, USA) data were analyzed. Chi-square test were done to find the relationship of prevalence with the risk factors.P< 0.05 is considered as statistically significant.

Results:

Total Caries prevalence was found to be 49.1%. The highest rate of caries occurrence, 55.4% was observed in children who belonged to the age group of 6–8 years. The def was shown to be more in the 9–11 age group and DMF in 12–15 age groups with 3.34 ± 3.74 and 2.18 ± 2.65 respectively. Statistically significant increase in caries is found in children whose both the parents were working (P < 0.001) and also in children who take sweets twice a day or more (P < 0.001).

Conclusion:

The prevalence of caries in 6–15 year old school children at Kannur is 49.1%. Working parents and high sugar consumption were found to be risk factors for caries in school going children.
Assessment of Tobacco Prevalence Among Employees Working in a Shopping Mall in Panvel, Navi Mumbai, Maharashtra, India
Authors: Dodeja Heena Lachhman , Dhameliya Vibhuti Bhupat , Ram Sabita M. , Thakkar Vaibhav Pravin
Published: March 2021

Background:

India is one of the countries in the world where prevalence of smoking and smokeless tobacco use is high. There is a need of cessation programs in various settings, and workplace with high prevalence can be targeted for the same. There are no studies conducted on prevalence of tobacco consumption among employees working at a shopping mall in this part of the country.

Aim:

This study estimates the prevalence of tobacco use among employees working in a shopping mall in Panvel.

Materials and Methods:

A descriptive cross-sectional study was conducted among the selected study population of 250 employees using the questionnaire adopted from the Global Adult Tobacco Survey (GATS). Informed consent was taken from every participant. The data were collected by means of a structured questionnaire adopted from GATS. Data collected were entered and statistically analyzed using the Statistical Package for the Social Sciences version 24.0 software (IBM, Armonk, NY, USA). Descriptive and inferential statistical analyses were carried out in the present study.P< 0.05 was considered statistically significant.

Results:

73.2% (183) of the employees were nontobacco users and 26.8% (67) consumed tobacco. The prevalence of smoking was 12% (30), and for smokeless, it was 11.6% (29), and 3.2% (8) consumed both forms. It was found that 12% (30) were willing to take help from the counselor to quit the habit and 13.2% (33) were not willing to take help.

Conclusions:

The present study reflects high prevalence rates of tobacco use among the employees. De-addiction programs and counseling sessions can be conducted for the employees willing to quit tobacco. New policies and tactics on tobacco use need to be explored to ensure the initiation of new tobacco control activities and monitor the existing tobacco control policies.
Knowledge, Attitude, and Behavior Related to Secondhand Smoke Exposure Among Pregnant Women With Smoking Spouses in Davangere City
Authors: Yavagal Puja Chandrashekar , Velangi Chandrabhaga S. , Desai Jagruthi Mutalik , Gupta Himani , Sheik Farheen S. , Kaushal Manika
Published: March 2021

Background:

Exposure to secondhand smoke among pregnant women is highly prevalent in India. Secondhand smoke exposure is linked with various serious deleterious health problems.

Aim:

The aim of this study was to assess knowledge, attitude, and behavior related to secondhand smoke exposure among pregnant women with smoking husbands in Davangere city.

Materials and Methods:

A descriptive cross-sectional questionnaire survey was conducted among 245 nonsmoking pregnant women with smoking husbands attending two antenatal clinics in Davanagere city using pretested, validated, investigator-administered closed-ended 18 item questionnaire. Responses to items were placed on a 3-point Likert scale. Statistical significance was set atP< 0.05. IBM SPSS Statistics for Windows, version 21 (IBM Corp., Armonk, N.Y., USA) was used for statistical analysis. Descriptive statistics were generated in terms of percentages.

Results:

The mean age of study participants was 26.22 ± 4.11 years. Majority of pregnant women were unaware of secondhand smoke exposure (>60%). They were unaware of its systemic complications such as cardiac problems, respiratory problems, and cancer. They were unaware of the harmful effects of secondhand tobacco smoke (SHS) on fetus/child (>60%) which indicated poor knowledge of participants toward harmful effects of secondhand smoke exposure majority of participants showed favorable attitude (>50%) and felt the need to get educated regarding SHS. Majority reported positive behavior by refraining themselves from secondhand smoke (>50%).

Conclusions:

Knowledge regarding secondhand smoke exposure among pregnant women with smoking husbands was poor. Inspite of having favorable attitude and behavior toward avoidance of smoke exposure, majority of women felt helpless in refraining their husbands from smoking.
An 8-Year Retrospective Analysis of Oral Submucous Fibrosis in Patients Visiting Dental College, Secunderabad
Authors: Prathima Vedati , Koneru Mrunalini , Sunil V. V. N. , Jois Harshavardhan , Reddy Madhusudhan
Published: March 2021

Background:

Oral submucous fibrosis (OSMF) is a chronic, progressive, scarring precancerous condition of the oral cavity seen predominantly in the Indian subcontinent and South East Asia. In India, the prevalence of OSMF has been increased over the past four decades from 0.03% to 6.42%.

Aim:

The study aims to provide an 8-year retrospective analysis of OSMF in patients visiting dental college, Secunderabad.

Materials and Methods:

A retrospective analysis was conducted from 2008 to 2016 in dental college, Secunderabad. Data were collected from patient's outpatient records from the department of oral medicine and radiology, year wise in the perspective of demographic details, history of nutritional deficiency, adverse habits, symptoms, clinical features, site involved, and mouth opening. There were no inclusion or exclusion criteria. All the cases which were provisionally diagnosed to be OSMF were included. The data were analyzed with SPSS package version 24. Chi-square test has been applied to check the association of different parameters such as gender, nutritional deficiency, adverse habits, area, palpable fibrous bands, and mouth opening with age.P< 0.05 was considered statistically significant.

Results:

The total patients were found to be 107. The mean age of the patients was 38 ± 12. Among the total patients, 86% were males and 14% were females. Among them, 3.7% were unskilled workers. Almost all of them (99%) reported no nutritional deficiency. Majority (51.4%) were having betel nut chewing habit, followed by tobacco chewing, intake of spicy food, smoking, and alcohol. Nearly 43% had limited mouth opening, followed by burning sensation and other symptoms. Palpable fibrous bands were present in 4.1% of the patients. Nearly 83.2% have been affected with OSMF in the buccal mucosa site. Grade 1 (>20 mm) mouth opening was present in 12.1% of the patients, 7.5% were having Grade 2 (11–19 mm), and 3.7% had Grade 3 (<10 mm) mouth opening. A significant association was found between age and adverse habits (P = 0.023). There was no significant association between age and sex (P = 0.924), nutritional deficiency (P = 0.766), area (P = 0.567), palpable fibrous bands (P = 0.221), and mouth opening (P = 0.155).

Conclusion:

Majority of the patients with OSMF were males who were < 30 years, having betel nut chewing habit and Grade 1 mouth opening.
Assessment of Self-Perception and Need for Orthodontic Treatment Using the Index of Orthodontic Treatment Need in Visually Impaired Students of Northern Karnataka, India
Authors: Singh Sanjeev B. , Jatti Roopa , Deshpande Sumedh R.
Published: March 2021

Background:

In recent years, the perception of an individual with a disability like visual impairment has been slowly evolving from the “forgotten” person to one who is recognized as needing treatment.

Aim:

The aim is to assess the self-perception and orthodontic treatment need in visually impaired (VI) students and to compare these with the control group (CG), and also to create awareness about malocclusion and orthodontic treatment in both groups.

Materials and Methods:

The present cross-sectional study was conducted in the special schools for the VI in the North Karnataka region. The CG was from the local schools in the same region. A total of 125 VI, 162 control students aged 11–19 years were included in the study. Determination of Esthetic Component (AC) and dental health component (DHC) in VI and control students were done. Chi-square test and Kappa statistics were used to compare between the study and the CG and to find out the agreement between the subjects and the orthodontist respectively. APvalue of <0.05 was considered to be statistically significant.

Results:

About 24% of VI and 6.1% of the control perceived to be in need of orthodontic treatment according to the AC. However, 24% of VI and 20.9% of control showed “definite need” of treatment based upon the DHC. The AC when compared between study and CG by Chi-square test, was found to be highly significant statistically with aP< 0.001.

Conclusions:

High percentage of VI students perceived a “definite need” as compared to control students based on AC. The data of the present study suggest that the VI students are more concerned about their malocclusion and perceive that they need orthodontic treatment.
Outcomes of total knee arthroplasty in a patient with poliomyelitis and distal femur malunited fracture
Authors: Alqarni Abdulhakeem S. , Alzahrani Khalid H. , Qutbuddeen Hamed S.
Published: March 2021

Severe deformity of the distal femur due to malunited fracture in a poliomyelitis patient is a rare entity. No reports are available in the literature about the results of total knee arthroplasty (TKA) in such cases. We report a 4-year follow-up of TKA in a 52-year-old woman who had postpoliomyelitis syndrome with malunited distal femur fracture associated with severe deformity and degenerative arthritis. TKA in poliomyelitis patients could reveal a good short-term functional improvement. We aim to demonstrate that even with the presence of deformity from previous trauma in polio cases, TKA would improve functional abilities. However, long-term follow-up is needed for similar cases.
Radiographic evaluation of third molar impaction
Authors: Khan Soban Qadir , Khabeer Abdul , Alyousef Nujood Ibrahim , Benrashed Mashael Abdullah , AlMaimouni Yara , Al-Thobity Ahmad , Gad Mohammed M. , Akhtar Sarfaraz
Published: March 2021

Background:

The impaction of third molar can compromise adjacent teeth by increasing the risk of developing dentoalveolar lesions.

Aims:

The aim of this study was to evaluate the prevalence of impacted third molar in association to patients' demographics and its angulation among patients who visited dental clinics at the College of Dentistry, Imam Abdulrahman Bin Faisal University.

Settings and Design:

Retrospective radiographic study of patients visiting Dental Hospital.

Subjects and Methods:

Data were obtained from the dental records and digital orthopantomogram (OPG) of included study sample.

Statistical Analysis:

The Chi-square test was used to determine the association of impacted third molars with sex and nationality, whereas another two methods, analysis of variance, and Tukey post hoc test were applied, respectively, to establish the association of impacted third molars with the age of the patients.

Results:

A total of 1286 OPGs were collected and analyzed for the suitability of the study. Of these 1068 patients fulfilled the criteria for inclusion in the study, among them, 206 (19.3%) had at least one impacted third molar. Female population had a significantly high prevalence of third molars compared to male (P = 0.02). Similarly, the age of the patients was found to be significantly associated with impacted teeth (P < 0.001); also, the vertical and mesioangular impactions were found in 46.5% and 32.2% of the patients, respectively.

Conclusion:

The study found a low female predilection for the prevalence of third molar impaction with highest inclination at the young age that decreases with the growing age. Vertical impaction had the highest prevalence followed by mesioangular angulation.
Association of serum osteopontin with first hospitalization and all-cause mortality after kidney transplantation
Authors: Yang Hsiao-Hui , Hsu Bang-Gee , Ho Ching-Chun , Lee Ming-Che
Published: March 2021

Objective:

Osteopontin (OPN) is involved in vascular calcification and atherosclerosis. We evaluated the association between serum OPN levels and the first postoperative hospitalization and all-cause mortality in patients who received kidney transplantation (KT).

Materials and Methods:

Seventy KT recipients were enrolled in this study from January to April 2012. The primary end point was first postoperative hospitalization or death. All patients were monitored in the outpatient clinics until June 30, 2017. Serum OPN level was measured by enzyme-linked immunosorbent assay.

Results:

During follow-up (median length, 65 months), 47 first postoperative hospitalizations and 8 deaths occurred. In comparison with serum median OPN levels, serum OPN level was positively associated with KT duration (P = 0.048), serum blood urea nitrogen (BUN; P = 0.043), and serum creatinine levels (P = 0.045) but negatively associated with estimated glomerular filtration rate (eGFR; P = 0.049). Hospitalized KT recipients had a higher prevalence of diabetes mellitus (DM) (P = 0.032), BUN (P = 0.002), and serum OPN level (P = 0.001) but lower eGFR (P = 0.030) than did patients not hospitalized. KT recipients who died had higher serum level of creatinine (P = 0.009) and OPN (P = 0.001) but lower eGFR (P = 0.036) than did surviving patients. Multivariate Cox analysis adjusted for age, gender, DM, hypertension, eGFR, KT duration, and steroid used showed that serum OPN level was associated with both first postoperative hospitalization (P = 0.049) and all-cause mortality (P = 0.017).

Conclusions:

Serum OPN level is a potential biomarker for first postoperative hospitalization and all-cause mortality in KT recipients.
Extreme horseshoe and circumanal anal fistulas-challenges in diagnosis and management
Authors: Garg Pankaj , Kaur Baljit , Yagnik Vipul D. , Menon Geetha R.
Published: March 2021

Objectives:

Extreme horseshoe anal fistulas are rare, and there are little data on the diagnosis and management of these fistulas.

Materials and Methods:

Patients with horseshoe anal fistula, in which the fistula tract encircled more than 75% of the anal circumference were included in the study. All patients were assessed by a preoperative magnetic resonance imaging (MRI). The patients were managed by a sphincter-sparing procedure. The continence was evaluated by an objective continence scoring system (Vaizey's scores).

Results:

1059 anal fistula patients were operated on over 7-years with a median follow-up of 36 months (range: 5–79 months). There were 47/1059 (4.4%) patients with extreme horseshoe anal fistulas. In 4/47 patients, the fistulas were complete circumanal (encircling anal canal completely). The mean age was 39.5 ± 10.9 years, M/F-41/6. The fistula was supralevator in 12/47 (25.5%), had an associated abscess in 28/47 (59.6%), and was recurrent in 33/47 (70.2%) patients. The tracts were intersphincteric in 27/47, transsphincteric in 2/47, and both (intersphincteric and transsphincteric) in 18/47 patients. All patients (n = 47) were managed by a sphincter-sparing procedure. Four patients were lost to follow-up. The fistula healed completely in 34/43 (79%) patients. There was no significant difference between preoperative and postoperative Vaizey's continence scores 0.031 ± 0.17 and 0.033 ± 0.18 respectively (P=0.90, Mann–Whitney U-test).

Conclusion:

Extreme horseshoe fistulas are rare, with an incidence of about 4% (in a referral practice). The missed diagnosis of circumferential tracts could lead to a recurrence. MRI was pivotal to confirm the diagnosis. Proper identification and management of internal opening and adequate drainage of all tracts were crucial for successfully treating extreme horseshoe fistulas.
Endovascular treatment of bilateral spontaneous dissection of common iliac artery involvement of the aorta and 3-year follow-up results
Authors: Li Xiang-Xiang , Hu Jun-Ding , Wu Cao , Geng Jia-Wei , Wang Meng , Wang Hao-Ran , Gao Wen-Bo , Wang Jun
Published: March 2021

Spontaneous dissection of the iliac artery is very rare. We report the case of a 49-year-old man who presented with spontaneous dissection of common iliac artery involvement of the aorta. We treated him by unibody bifurcated stent grafting and deployed the second stent-graft to prevent the collapse of the true lumen of the right iliac artery. For the sake of preserving pelvic blood flow, proximal type I endoleak was not treated. After 3 years, the endoleak still existed, without any aneurysmal formation. Further, the dissection of the distal external iliac artery still existence after 3 months, but the virtual disappearance after 3 years.
Automaticity for graphs of groups
Authors: Hermiller Susan , Holt Derek F. , Rees Sarah , Susse Tim
Published: March 2021

In this article we construct asynchronous and sometimes synchronous automatic structures for amalgamated products and HNN extensions of groups that are strongly asynchronously (or synchronously) coset automatic with respect to the associated automatic subgroups, subject to further geometric conditions. These results are proved in the general context of fundamental groups of graphs of groups. The hypotheses of our closure results are satisfied in a variety of examples such as Artin groups of sufficiently large type, Coxeter groups, virtually abelian groups, and groups that are hyperbolic relative to virtually abelian subgroups.
Prophetic Conflict in Jeremiah 27-28 and the Question of True and False Prophecy
Authors: Umeanolue Ikenna L.
Published: March 2021

The Old Testament text of Jeremiah 27-28 presents prophetic conflict between Jeremiah and Hananiah. Jeremiah proclaimed a message of God’s judgment against the rulers and the people of Judah because of their violation of the religious and the legal traditions of the nation but Hananiah opposed him preaching a message of peace and salvation and predicted the deliverance of Israelite nation from the hands of their enemies. Both claimed to have God’s authority. Jeremiah 27-28 provides a window into the problem of discerning a true prophet from a false one. Contemporary Nigerian Christians are also being challenged with such opposing prophecies by prophets who claim that their prophecies come from God. This study adopts exegetical method of interpretation and application of the message of Jeremiah 27-28 to the fact of truity and falsity in prophecy in contemporary Christianity. This study discovered that true prophetic office is a call, and not all comers’ affair. Prophecy lacks empirical proof and is sometimes manipulative and susceptible to barratry. The study further discovered that true prophets prophesy by the spirit of God while false Prophets prophesy from their own mind but also claim to do so by the spirit of God. Just like Prophet Hananiah, there are prophets who could be genuinely called but have refused to stay within their call because of loss of focus and desire for material gains. Thus the prevalent worldview of contemporary Nigerians concerning easy solution to life’s problems that leads to abuse of prophetic consultations needs to be changed.
The Dichotomy of Specialization: Is a Literature Teacher Necessarily a Language Teacher?
Authors: Anana Mariam
Published: March 2021

This study investigates the dichotomy of specialization in Literature and English language. In many primary and secondary schools in Nigeria, many teachers who teach Literature are the same teachers who teach English Language. This is responsible for lack of ultimate successes in academic performance, foundational establishment and progressive developments in Literature and English language. Set against the backdrop of the inseparability and non-specialization in individual subjects in question, the study examines the need for a dichotomy of specialization in English Language and Literature with a view to reducing the rate of errors and students’ failures in both subjects. Adopting the simple randomisation, the researcher uses selected primary and secondary schools in Lagos State as the case study; the paper raises four questions and these are: Can English Language teachers effectively teach poetic devices? Are segmental phonemes easily taught by Literature teachers? Can English Language teachers proficiently teach oral literature, literary criticism and non-African literature? Can Literature teachers competently teach stress and intonation? This research uses a qualitative approach and adopts The Speech Act Theory as its theoretical framework. Questionnaire of fifteen (15) items was used for data collection and the simple percentage was applied for data analysis. The researcher discovered that: It is not possible for English Languageteachers to effectively teach poetic devices. Segmental phonemes cannot be easily taught by Literature teachers. Students would lag behind in areas where teachers are not proficient in the subjects they teach. Also, it is not possible for a teacher to place equal emphasis on both English Language and Literature in classrooms. The study therefore recommends the need for a dichotomy of specialization in the two subjects so as to ensure effective teaching and learning of these subjects.
Occurrence and distribution of Organochlorine Pesticide Residues in Water and Sediments of Earthen Fish Ponds in South Western Kenya
Authors: Kiyuka Nyaundi Joseph , Getabu Albert , Onchieku James , Kinaro Zachary , Bassa Samuel , Nyamweya Chrisphine , Nyaboke Hilda , Getenga Zachary
Published: March 2021

Persistent organochlorine residues in the environment are a threat to ecological health of aquatic organisms and pose a health risk to both animals and human consumers. Organochlorine pesticides were determined in water and sediments collected during wet and dry season from selected riverine and earthen fish pond sites in high altitude catchment areas within Kuja River (Kenya) between August 2016–May, 2017. Analysis of DDT and metabolites, Hexachlorocyclohexanes (HCHs) isomers and cyclodienes using a gas chromatograph (GC), and electron capture detector (ECD), confirmed using GC - Mass Spectrometry (MS). Mean (± Standard error) results of DDTs, cyclodienes and HCHs in pond waters were:- below detection level (BDL) to 0.27±0.03µg/L, BDL to 0.11±0.00µg/L, and 4.39±1.01µg/L respectively; and BDL to 0.23±0.01µg/L, 1.20±0.005µg/L, and 1.71±0.02µg/L in river water respectively. Sediment mean OCPs contents were significantly (p<0.05) higher for Dieldrin (3.043±0.43µg/kg), Endrin (2.56±0.460µg/kg), Heptachlor (3.61±0.02µg/kg) DDT (2.97±1.32µg/kg), Endosulfan (6.31.27±1.051µg/kg), Methoxychlor (2.15±1.641µg/kg) and Lindane (2.96±1.32µg/kg), respectively. A longitudinal spatial distribution pattern was noted for both water and sediment OCPs contents, demonstrating that cyclodienes are predominant contaminants in point and non-point sources in water courses. The study recommends continuous monitoring of OCPs in upstream catchment areas for informed management and policy decisions on pesticide use.

Keywords: Kuja-Migori River; Organic contaminants; Organochlorine Pesticide.
After the Pandemic: Experimental Governance and the Foundational Economy
Authors: Morgan Kevin
Published: March 2021

The purpose of this article is to outline the convergence – an intellectual as well as a political convergence – of two concepts that will play a critically important role in fashioning a more inclusive and more sustainable model of development in the post-Covid world. The first concerns the concept of the Foundational Economy, which offers a new lens through which to view and value social and economic activity by highlighting the significance of a range of goods and services that loom large in terms of meeting human needs. The second concerns the concept of Experimental Governance, which offers a multilevel framework in which to understand place-based social innovation, a framework which overcomes the shortcomings of principal-agent models of collective action as well as the binaries associated with top-down versus bottom-up theories of change.
COLETÂNEA DE ESTUDOS EM ENGENHARIA CIVIL - UNINGÁ - 2020
Authors: BERVIAN ANDRÉ PAULO , BOM DANIEL CABELLEIRA , CAPITOL EDUARDO LONARDONE , FRANCISCHINI FELIPE VINICIUS , ESPERANDIO GABRIEL GUEDES , STAUB JOÃO OTÁVIO NICOLETTI , MONARIN JOÃO PEDRO , UNGARI LAUISE ALVES , STURION LEANDRO CORREIA , MENDES LUCAS BATISTA , LUVISOTTO LUCAS VIEIRA , DOURADO MATHEUS DA CUNHA , RISSATO MAURICIO CORREIA , MATIAS PEDRO HENRIQUE PEIXOTO , BRICHI RAFAEL CAMPANHA , PELEGRINI RAUL ANGELO , ALMEIDA RAYSSA DE , DOS SANTOS RODOLFO SANTIAGO , FELIPE WESLEY , NUNES YAN VICTOR DE ARAUJO , ZAMUNER LOURIVAL DOMINGOS , LUCENA ARTHUR FELIPE ECHS , FIESS JULIO RICARDO DE FARIA , ROMANICHEN ROMULO MENCK , FILHO ORLANDO DONINI , BERBERT ALLAN CASSIOLATO , NIRO LUCAS , DE OLIVEIRA RICARDO CARDOSO
Published: March 2021

Este e-book apresentará uma Coletânea de Estudos que se originou por meio de uma colaboração entre os discentes e docentes da área da Engenharia Civil da UNINGÁ – Centro Universitário Ingá.
Security Enhancement in Image Watermarking Using Combined Medium Sub-Band Wavelet Approach for Copyright Protection
Authors: Balakrishnan Sridhar
Published: March 2021

Watermarking in multimedia content has secured attractive approaches in research society since nowadays the transmission of digital content in wireless medium has been enormous. Along with the distribution of digital content, it is important to claim ownership. A non-blind detection technique is proposed in this paper. First, an original image undergoes the wavelet decomposition such as LL1, LH1, HL1, and HH2. Afterward, the medium level sub-band coefficients of the image are subject to the comfortable shares for merging. Next, one of the shares from the LH1 band is merging with another one of the shares in HL1 band. In this stage, the copyright mark is fetched into the merged sub-band coefficients. Finally, an inverse wavelet transform  is applied to receive the watermarked image. To prove the authentication, the original image and the watermarked image undergo the same operation and acquire copyright information. Experimental results achieve that the proposed approach can withstand various image processing attacks.
Geological Modeling for Nahr Umr Formation in Subba Oil Field, Southern Iraq
Authors: Menshed Mahdi
Published: March 2021

Geological modeling is very important in reservoir study, where it is described the framework of the structure and provided a distribution of petrophysical properties, the geological model helps to comprehend the fluid flow behavior affected by the heterogeneity of reservoir, also it is used to calculate oil initially in place and to choose the new well location in reservoir management. In this study, a geological model is built for Nahr Umr Formation based on data of 11 wells (SU-2, SU-3, SU-4, SU-5, SU-6, SU-7, SU-9, SU-10, SU-11, SU-13, and SU-14), including the location of wells, well tops, also contour map of the Nahr Umr Formation in Subba oil field is utilized. The structural model is constructed for the Nahr Umr Formation, which consists of two domes. The formation is composed of sandstone mainly interbedded with shale. The formation is divided into four units (B1, B2, C1, and C2) depending on well log data, each unit is divided into layers for getting better distribution of petrophysical properties, where unit B2 is divided to the number of layers is higher than other units due to its heterogeneity. The variogram is used as a geostatistical method to predict the petrophysical properties at unsampled locations, experimental variogram is calculated from well log data in a horizontal and vertical direction. The spherical variogram model shows a good fitting with the experimental variogram. Sequential Gaussian algorithm is used in distribution of petrophysical properties in a geological model which shows good petrophysical properties in unit B2 and unit B1, while units C1 and C2 are highly saturated with water.
DESIGN AND APPLICATION OF GLOW DISCHARGE CLEANING AT URAGAN-2M STELLARATOR
Authors: Kovtun Yu.V. , Moiseenko V.E. , Maznichenko S.M. , Lozin A.V. , Korovin V.B. , Kramskoy E.D. , Siusko Y.V. , Kozulya M.M. , Krasiuk A.Yu. , Listopad V.M. , Baron D.I.
Published: March 2021

For the Uragan-2M stellarator, a glow discharge cleaning (GDC) system is developed. An overview of the GDC system design is presented. The first experimental studies of GDC in an argon atmosphere have been carried out. The dependence of the breakdown voltage on the argon pressure is determined. The current-voltage characteristics of the gas discharge were measured as a function of the working gas pressure also in presence of a magnetic field.
PARAMETERS OF HYDROGEN PLASMA STREAMS IN QSPA-M AND THEIR DEPENDENCE ON EXTERNAL MAGNETIC FIELD
Authors: Ladygina M.S. , Petrov Yu.V. , Yeliseev D.V. , Makhlai V.A. , Kulik N.V. , Staltsov V.V.
Published: March 2021

Present experimental studies are aimed at analysis of hydrogen plasma stream parameters in various working regimes of QSPA-M operation. Temporal distributions of plasma electron density are reconstructed with optical emission spectroscopy. The magnetic field influence on plasma streams parameters is analyzed. It is shown that in regimes with additional magnetic field the plasma electron density increases by an order of magnitude in comparison with a density value without magnetic field. The plasma velocity and energy density parameters as well as their temporal behaviors were estimatedin different operating regimes of QSPA-M facility. Features of plasma visible radiation were analyzed. This information is important for QSPA-M applications in experiments on interaction of powerful plasma streams with material surfaces.
AN APPLICATION OF MICROWAVES REFRACTION FOR INHOMOGENEOUS PLASMA DIAGNOSTIC
Authors: Siusko Y.V. , Kovtun Yu.V.
Published: March 2021

A brief review of the main microwave diagnostics methods of inhomogeneous plasma based on the refraction of microwaves is given. These methods make it possible to determine the plasma density distribution, the magnetic field distribution, the electron collision frequency, and the electron temperature profile. In addition, the determination of the average density of the peripheral plasma layers and the local inhomogeneities of the rotating plasma are also possible. The effect of refraction on the accuracy of determining the plasma parameters by using microwave methods for plasma diagnostics is considered.
Kurumsal Organizasyonlardaki Liderlik Tipleri Verimliliklerinin Swara Yöntemiyle Değerlendirilmesi
Authors: DOĞANER Mustafa , AYDIN Mustafa Seçkin , İNCİOĞLU Cahit
Published: March 2021

Günümüz organizasyonlarında çeşitli liderlik türleri uygulanmakta ve her biri çalışanlar üzerinde etki bırakmaktadır. Bu bağlamda verimli olacak bir liderlik türünün belirlenmesi organizasyon ve yönetim açısından önem taşımaktadır. Bu çalışmada liderlik ve motivasyon kavramları ile liderlik türleri teorik olarak açıklanmıştır. Kurumsal organizasyonlarda uygulanan liderlik türlerinin verimliliklerinin tespit edilmesi çalışmanın amacını oluşturmaktadır. Araştırmada 11 adet liderlik felsefesi ele alınmış ve kriter olarak belirlenen bu felsefeler 4 şirket sahibi ve 7 yönetici olmak üzere 11 uzman tarafından değerlendirilerek veriler elde edilmiştir. Bu değerlendirme çok kriterli karar verme yöntemlerinden, SWARA metodu kullanılarak yapılmıştır. Kurumsal firmalarda çalışan olarak bulunan kişilerin, demokratik ve esnek yönetim-liderlik biçimlerini tercih ettikleri, şirkette hisse sahibi olan yöneticilerin biraz daha kontrolcü ve geleneksel liderlik şekillerine de önem verdiği bulguları görülmüştür. Araştırma sonucunda demokratik liderlik, organizasyonlarda en verimli görülen liderlik türlerinde ilk sırada yer alırken onu sırasıyla dönüşümcü liderlik ve karizmatik liderlik izlemiştir. Ayrıca otokratik liderliğin, en az verimli görülen liderlik türü olduğu sonucuna ulaşılmıştır.
System and Elements, Control and Management of Election Fraud -Tool of Global Masonis Mafia_Driven Elite and its Deep State - Imitation Democracy and Management and Control Respective State and Examples of The US Elections 2020
Authors:   Scientific Research Institute Dobrev & Halachev JSC, Dobre Lord Prof. Momtchil
Published: March 2021

Lord prof PhD PhD Momtchil Dobrev-Halachev developed 2010 “Financially banking resource-based technological mafia-driven materialism” as a based principle materialismus since more than 17 century., 2010 “Theory and praxice of the Mafiotismus” and 2001 “Theory of the mafia ”. The 2020 US elections have proven exactly how the falsification scheme, fraud in elections organized by the elite, the oligarchy, the kleptocracy and the mafia in the United States works. This mafia, which aims at the NEW WORLD ORDER and the enslavement of the entire planet and all nations. As president, Trump opposed this mafia, but it tricked him into rigging the election.
Tinjauan Orientasi Efektivitas Rencana Pengelolaan Program Kawasan Konservasi Kementerian Kelautan dan Perikanan
Authors: Soemodinoto Arisetiarso , Rusandi Andi , Hakim Amehr
Published: March 2021

Pengelolaan yang efektif kini telah menjadi bagian tak terpisahkan dari upaya untuk menangani masalah ‘kawasan konservasi kertas’, dan sekaligus untuk memfasilitasi pembangkitan manfaat-manfaat ekologi dan sosial-ekonomi kawasan konservasi laut. Agar dapat dikelola secara efektif setiap kawasan konservasi laut wajib dilengkapi dengan rencana pengelolaan (RP) berorientasi efektivitas pengelolaan. Makalah ini menyajikan persyaratan yang harus dipenuhi sebuah RP agar ia layak disebut berorientasi efektivitas pengelolaan, yaitu: (1) daftar keanekaragaman dan sumberdaya hayati terbarukan yang terancam oleh kegiatan manusia; (2) kegiatan-kegiatan manusia yang secara langsung maupun tak-langsung mengancam keberlanjutan keanekaragaman dan sumberdaya hayati; (3) strategi untuk menangani kegiatan-kegiatan manusia yang mengancam keanekaragaman dan sumberdaya hayati; dan (4) tujuan dan sasaran pengelolaan kawasan yang dinyatakan dengan jelas dan terukur. Untuk memberi contoh bagaimana meninjau orientasi efektivitas pengelolaan sebuah RP, persyaratan diterapkan pada rencana pengelolaan dan zonasi (RPZ) salah satu kawasan konservasi perairan, pesisir dan pulau-pulau kecil yang berada di bawah yurisdiksi Kementerian Kelautan dan Perikanan, yaitu Taman Wisata Perairan (TWP) Gili Matra. Selain menyarankan isi dan cara menyusun RP berorientasi efektivitas pengelolaan, makalah ini juga sangat menyarankan agar semua RP yang sudah ada ditinjau-ulang dan direvisi menjadi berorientasi efektivitas pengelolaan.
Kearns Sayre Syndrome: A Mitochondrial Disorder
Authors: Cisneros Anali , Henderson Jeffrey O.
Published: March 2021

Kearns–Sayre syndrome (KSS) is a pleiotropic disorder caused by non-specific spontaneous deletion of a large amount of genetic material from mitochondrial DNA (mtDNA). Aside from patients having mtDNA defects there are also autosomal mutations in nuclear DNA, indicating KSS is not caused by a single gene mutation, but is most likely the result of mutations in genes forming a common biochemical pathway. KSS is characterized by a wide array of symptoms including: ophthalmoplegia, pigmentary retinopathy, ataxia, cardiac conduction defects that later develop into cardiac complications, and brain abnormalities. This review considers the association of deletions in mtDNA with a decrease in mitochondrial function and the pathogenetic role of the dysfunctional mitochondria by analyzing different variants of the mitochondrial genome. Despite there being no curative treatment for these patients, some possible disease modifying therapies have been proposed such as folinic acid supplementation and intravenous arginine therapy.