bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Bimetallic Doping in Cobalt Titanate for Methane Reforming
Authors: Jain Disha
Published: June 2019

Supported Ni catalysts are extensively studied for methane reforming due to their high catalytic activity and low cost. However, these catalysts undergo deactivation due to coke deposition and oxidation of Ni particles. In the present work, Ni and Pt substituted CoTiO3 were synthesized and studied for steam (SRM) and dry (DRM) reforming of methane. The catalytic activity of monometallic and bimetallic Ni-Pt catalyst was compared for SRM and reducibility studies were done to highlight the change in metal-support interaction in the synthesized samples. Ex situ and in situ characterization were performed to understand the change in catalyst surface and the nature of surface intermediates formed during the reaction. Consequently, surface reaction mechanism was proposed and kinetic parameters were determined by fitting experimental data.
Out-of-pocket expenditures for HIV in the Dominican Republic: findings from a community-based participatory survey
Authors: Chaumont Claire , Oliveira Carlo , Chavez Enrique , Valencia Jaime , Villalobos Dintrans Pablo
Published: June 2019

Objectives. The aim of this study was to estimate out-of-pocket expenditures incurred by individuals with HIV in the Dominican Republic. The study utilized different definitions and components for these expenditures and differentiated the results by wage ranges.

Methods. Data was obtained from an in-person survey of people living with HIV. The study was developed and implemented in collaboration with Dominican grassroots organizations and networks of people with HIV, through a process of community-based participatory research.

Results. The mean HIV-related expenditure reported by individuals in the sample in the last six months prior to the survey was in US$ 181; 15.4% of this total was spent for transportation and housing and costs to access the HIV facility. The mean expenditure reported by individuals for their current visit to an HIV center was US$ 10. These out-of-pocket expenditures exhibited regressivity, with lower-wage patients spending proportionally more to receive care. The results highlight the importance of considering other resources required to access treatment, such as lodging expenses and the time needed to travel to an HIV center and then to wait to be seen by a care provider.

Conclusions. There should be more focus on expenditures made directly by people with HIV in the Dominican Republic so that these payments do not become a barrier to accessing health care. Using a community-based participatory design can ensure that such data can be leveraged to address the specific barriers to care that are faced by individuals with HIV.
Identification and characterization of lactic acid bacteria isolated from some
medicinal and/or edible Philippine plants
Authors: Saguibo J.D. , Mercado M.A. , Maldia S.T. , Jimeno B.T. , Perez M.T.M. , Calapardo M.R. , Elegado F.B.
Published: June 2019

Probiotics research on lactic acid bacteria (LAB) continues to be paramount in the
development of nutraceutical or functional foods. In this study, 47 selected Philippine
plants having nutritional (edible such as vegetables) and/or medicinal values (therapeutic),
were collected, from which selected fruit and leaves were subjected to LAB enumeration.
Among these, 46.7% plant leaves reported to have strong antimicrobial property resulted
in non-isolation of LAB while edible plant leaves with less or no antimicrobial properties
generally gave numerous LAB isolates. Isolates coming from ripened guava (Psidium
guajava L.), lobo-lobohan or cape gooseberry (Physalis peruviana L.) fruit, parsley
(Petroselinum crispum), pandan (Pandanus amaryllifolius), spinach (Spinacea oleracea),
leek (Allium ampeloprasum var. porrum) and niyog-niyogan (Quisqualis indica L.) leaves
were identified through partial 16S rRNA analysis and tested for probiotic properties.
Overall, Streptococcus luteciae Lb17 from ripe gooseberry fruit exhibited the highest
antimicrobial activities against Staphylococcus aureus BIOTECH 1526, Escherichia coli
O157: H7 BIOTECH 10311 and Bacillus cereus BIOTECH 1509. On the other hand,
Enterococcus hirae (H and S63) from stevia were susceptible to streptomycin at minimum
inhibitory concentration or MIC of 128 ug/mL). Lactobacillus plantarum F39 and all the
other strains tested, meanwhile, was susceptible to ampicillin at MIC of 2 ug/mL and
0.125 ug/mL. Results were lower or equal to the established cut off value indicating the
absence of antibiotic resistance genes among the identified strains, except for Pediococcus
(Par5 and NN39) which showed resistance against streptomycin. Further investigation is
needed to rule out the possibility of transfer of antibiotic resistance to pathogens present in
the gut. All isolates tested were able to survive at artificial gastric juice (pH 2), revived at
the simulated intestinal fluid (pH 8), and exhibited minimal titratable acidity and diacetyl
production. For genetic screening of plantaricin genes, F39 possesses both plantaricin EF
and plantaricin J, while Lactobacillus fermentum F36 has plantaricin EF. Both isolates
were subjected to DNA fingerprinting. Such findings on the local isolates’ probiotic
properties suggest the possibility of incorporating them into different plant-based probiotic
foods.
Non-financial Indicators of Fraudulent Bankruptcy
Authors: Gorodilov M. A. , Belyaev A. S.
Published: June 2019

The article considers what indicators in addition to the existing methods could be used as indication of deliberate bankruptcy. The analysis of the patterns identified during forensic accounting examinations in order to find the signs of fraudulent bankruptcies shows that there should exist non-financial indicators of a company’s preparation to fraudulent bankruptcy. The authors analyze the economic activity of seven organizations in the period preceding their filing for bankruptcy. These data were systemized and subjected to further examination. The analysis resulted in determining two non-financial indicators of the fraudulent nature of bankruptcy. The indicators identified can be used by court receivers when they analyze financial and economic activities of the companies, as well as by forensic accountants in cases of bankruptcy.
Features and Analytical Support for the Accounting System of Transportation Holding: Prospects of Development
Authors: Mihaylova Z. V.
Published: June 2019

Features of development of the accounting system of transport holding at the present stage determine the approaches to the formation and structuring of the information base. The exclusive needs of interested users in the received information are revealed, its significant characteristics, which are determined by the trends of strategic accounting, are substantiated. In the course of the study of the practical application of the centralized accounting model, the negative impact of some factors on the final reporting data of the transport complex enterprises was established. The critical point of view of the applied accounting system and its impact on the information indicators of the transport complex as a whole and on individual business structures is substantiated. The analytical section of the accounting data of the transport holding has a strategic focus. The formation and selection of specific indicators depends on the strategic objectives. The article offers an alternative to the existing approach to the applied accounting principles, in particular for solving strategic tasks, through the use of indicative budgeting methods with simultaneous change of accounting rules of the transport holding.
Analysis of the Effectiveness of the Pricing Policy of the Organization: Practical Aspect (on the Example of JSC “Verkhnebakansky Cement Plant”)
Authors: Kovaleva I. P.
Published: June 2019

The theoretical concepts of evaluating the effectiveness of the pricing policy of an organization are fairly fully represented in both Russian and foreign sources. However, the practical aspects of this issue, often related to the specifics of the activities of each individual domestic enterprise, its financial and pricing policies, have their own characteristics. This is especially true in conditions of instability, when commercial organizations are forced to look for various ways and methods to optimize their activities. One of such methods is the study of the financial results of the organization’s activities when applying various pricing tactics, for example, using discounts and without them for regular customers. To achieve this goal, it is recommended to conduct a variety of analytical procedures based on accounting data. At the same time, projected financial results for the enterprise can be calculated and the main directions for optimizing its pricing policy will be selected. For example, improving: pricing in terms of upgrading information support; pricing process through the use of new methods in the field of planning and forecasting prices; pricing policy by changing its main elements such as methods, strategies and tactics. Taking into account the specifics of the organization’s activities, various directions and tools are offered for using these methods in pricing. For the cement industry in particular one of the ways to improve the efficiency of the pricing process can be offering retail sales at the price of the main price list. Thus, by analyzing the pricing policy of an enterprise and making conclusions about the influence of various factors on its effectiveness, it is possible to significantly improve the organization’s activities, having a positive effect on its financial results, both in the current period and in the future.
OPINIONS OF SLOVAK ACADEMIC STAFF AND STUDENTS ON THE PROFESSIONAL COMPETENCES OF ACADEMIC TEACHERS
Authors: Kasáčová Bronislava , Guffová Daniela
Published: June 2019

The paper is a result of comparative study conducted over the period 2017–2018 within
the International Visegrad Fund project No. 21720008. Four countries are included in the project, namely Ukraine, Poland, Czech Republic and Slovak Republic. The opinions of university teachers and students on the competences of academic teachers are investigated and compared within the study. The specifcs of Slovak view and legislation of professional competences are presented in the paper. Moreover, the analysis of data obtained in Slovak universities based on comparison of teachers’ and students’ opinions on academic teachers’ competences are described.
PEDAGOGICAL MONITORING AS TECHNOLOGY OF MANAGING QUALITY OF EDUCATION
Authors: Kozak L.
Published: June 2019

The article shows problematic issues of preschool education qualities; the essence and peculiarities of pedagogical monitoring as a technology of quality management education are considered. The pedagogical monitoring is continuous, long-term observation, control and evaluation of educational process and self-management as well as forecasting the dynamics of its development by analyzing the received data. Pedagogical monitoring refers the technology of educational activity; it focused on obtaining objective information of the course and results of the educational process, forecasting its development and management. The objects of monitoring can be both separate subsystems of education, as well as various aspects and processes taking place in this system: the content of education, educational process and its results, the quality of teachers’ activities, quality of management, the quality of mastering of academic disciplines, the formation of personal qualities of graduates. The main purpose of monitoring is to promptly identify all changes taking place in the field of education and predict further ways of developing the education system. Based on monitoring data it becomes possible to carry out correction of the activity of various sections of the functioning of the educational system, and increase the skill of teachers. The article highlights the process of organization and application of monitoring in the system of preschool education.
INTERACTION OF THE EDUCATIONAL PROCESS PARTIES AS GUARANTEE OF HIGH QUALITY OF EDUCATION
Authors: Stebletskyi A.
Published: June 2019

Our country relies on system of education in its development. The laws of Ukraine “On Higher Education” (2014) and “On Education” (2017) were adopted. The philosophical aspect of topical trends in education is considered in life-long helping an individual to fulfil him/herself as a professional citizen and personality. It is obvious, that in such case, the access to education and educational services should increase. This fact exacerbates the issue of improving the quality of education. One of the directions of increasing the quality of education is to increase the quality of educational activities. An important reserve for the quality of educational activities is the constructive interaction of participants in the educational process.
The article analyses the nature of interaction of the parties to the educational process in the context of their educational activities. The structure of optimal self-organization of the parties’ educational activities is determined. The problems in studying the quality of educational activities are stated. The conditions, factors and criteria determining the nature of the interaction of educational activity parties are described.
The conditions of educational process development in the higher schools are determined by its nature: the educational process based on the research basis, the interaction between the parties, the practice-aimed educational process. The conditions of development of educational process parties’ interaction are determined by interdependence of processes being the basis of their educational activities self-organization. The important criteria for constructive nature of the parties’ interaction in the educational process include benevolence, openness, impartiality, aspiration for perfection, and activity.
Higher education reform can not take place without the continuous growth of higher education quality. Higher education should become even more powerful source of development of our country.
FORMATION OF MOTIVATION OF HIGH SCHOOL STUDENTS TO STUDYING MATHEMATICS IN THE PROCESS OF ICT APPLICATION
Authors: Kоzyr М. , Pavlyuk O.
Published: June 2019

of the nature of its origin and development, its structure, types and levels. The theoretical approaches, main characteristics and peculiarities of formation of motivation in senior pupils are determined. The role of information and communication technologies in raising the level of motivation in high school students in mathematics lessons is considered.
During the study, we used the following basic methods:
— theoretical: analysis of philosophical, psychological, and pedagogical literature with the aim of studying, generalization and systematization of scientific materials on the research problem; the selection of theoretical substantiation of the content, forms, methods, means of forming the motivation of senior pupils in the process of application of ICT;
— empirical: observation, testing, questioning, studying and generalization of modern pedagogical experience in order to substantiate the effectiveness of tested content, forms, methods and means of forming motivation of senior pupils in the process of ICT application.
The methodical recommendations developed and tested in the process of experimental work demonstrate the following possibilities of the use of ICT as a means of development of students’ motivation: formation of cognitive motivation, excitation of interest in the study of an object; development of visual thinking; formation of the ability to create, apply and transform patterns and schemes for solving educational and cognitive tasks; organization of independent search cognitive and research activity of students, their activity on independent use of ICT for the search and learning of educational information; implementation of differentiated control, self-control and correction of mathematical knowledge and skills of students.
As a result of an experimental study with a sufficient degree of probability, confirmed by a statistical evaluation of the results, it is found that the implementation of the identified in the study of organizational and pedagogical conditions and methods of using ICT as a means of activating cognitive activity of students contributes to a significant increase in the level of motivation students in the study of mathematics.
THE STUDY OF UNIVERSITY PROGRAMS IN THE CZECH REPUBLIC FOCUSED ON EDUCATION
Authors: Malach Josef , Havlásková Tatiana
Published: June 2019

The paper presents an overview of study felds at universities in the Czech Republic, which are aimed
at achieving the qualifcations required for the performance of educational professions, respectively
educational roles. The fundamental diﬀerentiation criterion is their main focus on one of the aspects
of complex education, specifcally education and upbringing. Professions of an educator, special
and social pedagogue or a leisure time teacher are considered to be the professions predominantly
focused on education. University education for the previously stated occupational subgroups
implemented so far is built on study programs that have been created by teams of academic
staﬀ and accredited by the Accreditation Commission. They are usually based on the erudition
and personal experience of their authors and assessors and without any professional standards.
The amendment to the University Education Act has fundamentally changed both the procedures
for the accreditation of study programs and the functioning of the newly established accreditation
institution — the National Accreditation Ofce. The study introduces the legal standards applicable
to accreditation procedures as well as the fundamental changes in functioning of universities due
to these rules. Apart from that, the curriculum design includes current education and training
practices with a number of national (both positive and negative) characteristics and oddities
identifed on the basis of the (inter)national research, analysis, monitoring or good practice. Today´s
educational reality is the result of the involvement of stakeholders who reﬂect it critically in terms
of their expectations and needs. They provide feedback to universities necessary for the innovations
of graduate profles, the aims and content of their studies and the future educators´ teaching and
learning processes. With regard to the implementation of the national digital education strategy,
the possibilities of universities to respond to its objectives by preparing new subjects for teacher
education are mentioned.
Evaluación de la infectividad de comunidades de hongos micorrízicos arbusculares
Authors: Bonilla Loor Mario Javier , Solórzano Zambrano Liceth Janina
Published: June 2019

La infectividad, definida como la capacidad de una especie aislada para establecer rápidamente una colonización micorrízica extensa en las raíces de las plantas de prueba, el presente trabajo evaluó en HMAs seleccionados y aislados del campo experimental. Se realizaron diferentes experimentos para evaluar la germinación de esporas y el crecimiento de hifas, utilizando el método "sándwich" o las placas de múltiples pocillos. En los aislamientos de F. mosseae, las tasas de germinación de esporocarpios oscilaron entre 52% y 89%, las esporas de R. fulgida mostraron 69% de porcentaje de germinación. La capacidad de los aislamientos de HMAs para formar apresorios que dan lugar a puntos de entrada que colonizan las raíces fue variable, y los valores variaron de 1.6 a 6.1 puntos de entrada cm raíz-1. En consecuencia, la colonización micorrízica osciló entre el 2% y el 31%.
ПИТАННЯ ІНСТИТУЦІОНАЛЬНОЇ ЕКОНОМІЧНОЇ ТЕОРІЇ У ПРАЦЯХ Г.Ф. СИМОНЕНКА
Authors: Strishenets Nicholas , Pavlova Olena , Pavlov Konstyantyn , Kupchak Volodymyr
Published: June 2019

У статті висвітлюються наукові здобутки відомого українського вченого -  економіста Г.Ф. Симоненка, співзвучні з інституціональною економічною теорією. Показується внесок ученого у розширення та поглиблення знань з даного напрямку економічної науки, зокрема про дію економічних законів у матеріальному і нематеріальному виробництвах. Адже розробка наукової програми подальшого соціально-економічного розвитку України передбачає вивчення теоретичних напрацювань вчених економічної науки, які можна було б використати для вироблення власної, національної моделі реформування економіки на ринкових засадах. Метою статті є вивчення творчих досягнень відомого українського вченого - економіста Г. Ф. Симоненка, де порушуються питання, співзвучні з інституціональною економічною теорією або дотичні до неї. В процесі дослідження підвищена увага зверталася на розкриття таких завдань, як: ставлення науковця до матеріального і нематеріального виробництв, їх взаємозв’язок та умови існування.
РИНОК ОРГАНІКИ ОВОЧІВ ТА ФРУКТІВ: ПОРІВНЯЛЬНА ХАРАКТЕРИСТИКА УКРАЇНА ТА СВІТ
Authors: Bochko Olena , Wasielewski Mirosław , Rozhko Nataliya
Published: June 2019

У статті проведено аналіз обсягу органічних сільськогосподарських земель світу та України. Встановлено зростання даного показника за 2010-2017 рр. в світі майже в два рази, який станом на 2017р. становив у 69,8 млн. га., а в Україні за досліджуваний період аналогічний показник зріс у 1,6 раза та в 2017р. становить 421500 га. Обґрунтовано, що найвищу питому вагу органічних сільгосп­угідь в загальній структурі країни можна спостерігати в Уруйваї – 7,42%, дещо менше - в Італії – 4,95 % та Іспанії – 3,89 %, найменшу - в Китаї – 0,17 %, в Україні цей показник становить 0,68%. Доведено, що в Україні спостерігається позитивна динаміка зростання кількості господарств, що займаються виробництвом органічної продукції у 3,4 раза та в 11 разів збільшення обсягів ринку органічних продуктів, проте навіть така позитивна динаміка далека від світових показників.
ЕВОЛЮЦІЯ РОЛІ ЛЮДСЬКИХ РЕСУРСІВ В УПРАВЛІННІ БІЗНЕС-СТРУКТУРАМИ
Authors: Lipych Lubov , Khilukha Oksana , Kushnir Myroslava , Mokhniuk Anna
Published: June 2019

В статті обґрунтовано, що зі зміною особливостей розвитку виробництва та суспільства, змінювалася праця, а відповідно і вклад людських ресурсів. Криза «етики праці» зумовила  перехід до концепції управління «людськими ресурсами». Сучасні форми управління людськими ресурсами бізнес-структур трактують працівників як  вартість, здатну до швидкого і багатогранного розвитку, тобто відбувся перехід до управління людським капіталом, яке виходить за рамки конкретного підприємства і спонукає перетворенню традиційного суб'єкта господарювання у складну організаційну структуру. Організаційні зв'язки цієї структури визначають методи контактів персоналу бізнес-структури з внутрішнім і зовнішнім середовищем, а також можливості внутрішньої міграції працівників. Доведено, що в цьому процесі вплив на людей як капітал трансформується в нову цінність – управління капіталом знань бізнес-структури.
КОНЦЕПТУАЛЬНІ ЗАСАДИ ЗАБЕЗПЕЧЕННЯ КОРПОРАТИВНОЇ БЕЗПЕКИ ПІДПРИЄМСТВ
Authors: Shyra Taras
Published: June 2019

Історія виникнення та розвитку корпорацій має давні історичні корені, але в Україні зроблені лише перші кроки, які покликані сприяти поширенню цієї найбільш ефективної форми організації бізнесу. Використання переваг корпорації в конкурентній боротьбі можливе за умови забезпечення на належному рівні її корпоративної безпеки. Сьогодні існує лише кілька визначень терміну «корпоративна безпека», а теоретико-методологічні підходи, методичні основи та практичні рекомендації перебувають на стадії формування. Обґрунтовано власне визначення корпоративної безпеки як діяльності спрямованої на досягненні взаємоузгоджених корпоративних інтересів шляхом  ефективного використання наявних ресурсів та захисту від негативної дії загроз, що уможливлює формування безпечних умов для стійкого розвитку підприємства. Визначено та обґрунтовано концептуальні засади забезпечення корпоративної безпеки на українських підприємствах.
РОЛЬ ТА ЗНАЧЕННЯ ГАЗОТРАНСПОРТНИХ ПІДПРИЄМСТВ В УКРАЇНІ ТА ЇЇ РЕГІОНАХ
Authors: Korotya Miroslav
Published: June 2019

В статті досліджено інституційне забезпечення діяльності газотранспортних підприємств. Окреслено організаційно-економічний базис функціонування газотранспортних підприємств. Здійснено огляд теоретичних підходів до розуміння «газотранспортне підприємство» та шляхом систематизації дано уніфіковане визначення даного поняття. Простежено діюче нормативне забезпечення існування газотранспортної сфери. Розроблено організаційно-економічний базис забезпечення діяльності газотранспортних підприємств, запропоновано наступні організаційно-економічні шляхи ефективності діяльності газотранспортних підприємств.

У напрямі лібералізації національного газового ринку:

- дотримання правил та обов’язків Енергетичної стратегії України на період до 2030 року;

- збільшення частини залучення приватного капіталу;

- підвищити якість наданих газових послуг;

- залишити трансакційні витрати;

- адаптувати вихідні положення Кодексу газотранспортної сфери.
НОРМАТИВНО-ПРАВОВЕ ЗАБЕЗПЕЧЕННЯ ТА РЕГУЛЮВАННЯ ПРОЦЕСУ РОЗПОДІЛЕННЯ ГАЗУ В РЕГІОНІ
Authors: Novosad Oksana
Published: June 2019

У статті розглянуто основні та вторинні нормативно-правові акти, що забезпечують процес регулювання у газорозподільних мережах (ГРМ); проаналізовано особливості законодавства, щодо взаємодії постачальника та споживача природного газу стосовно укладання договорів, надання послуг та їх оплати, відповідальності сторін та ін.; з’ясовано практичну необхідність функціонування чіткої регулюючої бази, що є запорукою прийняття вірних рішень, уникнення спірних питань між постачальниками та споживачами природного газу, підвищення ефективності роботи суб'єктів господарювання; обґрунтовано необхідність змін та вдосконалень у законодавстві за для отримання можливості формування конкурентного ринку газу з метою виходу на рівень європейських країн.
Između diskursa o prostoru i diskursa
prostora
Authors: Bertoša Mislava
Published: June 2019

U
članku se iz perspektive semiotike prostora analiziraju temeljni dokumenti o
osnivanju, ustroju i prostornim preinakama Zavoda za umobolne u Stenjevcu.
Oslanjajući se na analitičko-diskursne modele ispituje se način na koji je u njima legitimiziran diskurs o prostornom
ustroju stenjevečkog Zavoda i izdvajaju tri temeljna principa (estetski,
ekonomski i utilitarni) s pomoću kojih je legitimizacija postignuta, te se
identificiraju temeljni topoi i
ispituje njihova argumentacija u različitim kontekstima. Posebno se
analiziraju tekstovi u kojima različiti stručnjaci raspravljaju o budućem
spacijalnom ustroju Zavoda i odmjeravaju prednosti i nedostatke dvaju
temeljnih modela spacijalne organizacije ludničkih prostora u 19. stoljeću –
paviljonskog i monolitnog. Rezultati analize pokazuju
su da su neka od temeljnih obilježja diskursa o prostornom uređenju Zavoda u
Stenjevcu ekonomičnost, povoljnost i oportunost te funkcionalnost i
svrhovitost. Oni se promatraju u sprezi s kontekstom razdoblja, ponajprije s
prevladavajućim društvenim vrijednostima i devetnaestostoljetnim idejama o
liječenju umobolnika.
Preparation and Properties of Graphene-based Inorganic Nanocomposites
Authors: Liao Qing , Song Tingting
Published: June 2019

Graphene is a two-dimensional hexagonal monoatomic layer crystal composed of carbon atoms, which exhibits the shape of a honeycomb and plays an important role in the fields of optics and mechanics. It also has the advantages of high specific surface area, strong chemical stability and special planar structure. It is an ideal carrier for carrying various inorganic compounds and is suitable for the development of high performance graphene-based inorganic nanocomposites.[1] Based on this, the paper introduces the characteristics of graphene, expounds the related content of graphene-based inorganic nanocomposites, and studies the preparation methods and properties of graphene-based inorganic nanocomposites.
Preparation of Graphene Materials and Their Applications in the Field of Electrochemistry
Authors: Liao Qing , Song Tingting
Published: June 2019

In the development of modern society, many new materials and technologies have been integrated into the development of various industries. As a new type of two-dimensional carbon nanomaterials, graphene has great advantages in physical and chemical properties and is widely used in various fields of development. Among them, the electrochemical method is one of the important ways to prepare graphene materials, which has the characteristics of quickness and environmental protection, and can effectively produce a large amount of high-quality graphene and its composite materials. Based on this, the paper introduces the preparation method of graphene materials and studies the application of graphene materials in the field of electrochemistry.
New Anticonvulsants: Interchangeability Issues and the Use of Generic Anticonvulsants in Clinical Practice
Authors: Arkhipov V. V. , Sokova E. A. , Gorodetskaya G. I. , Demidova O. A. , Aleksandrova T. V.
Published: June 2019

This article looks into interchangeability and therapeutic equivalence of innovator and generic anticonvulsants — the first-generation and new antiepileptic drugs (AEDs). The results of a number of clinical trials assessing therapeutic equivalence of generic AEDs support the opinion that these medicines could only be substituted provided an ultra-cautious approach is used, even if the case involves only one International Nonproprietary Name, including, but not limited to different dosage forms of one and the same product. The aim of the study was to analyse factors leading to incorrect assessment of therapeutic equivalence of new and generic anticonvulsant drugs, and to improve methodological approaches to conducting clinical trials of these products. The paper cites data from Russian and foreign sources which state that the substitution of AEDs in some patients in full remission may result in adverse reactions or relapse of seizures. The analysis of the experience of scientific, expert, and regulatory institutions made it possible to develop a course of actions to be used when substituting AEDs and conducting clinical trials that assess therapeutic equivalence of new and generic anticonvulsants. The proposed methodology will help minimise potential health risks brought about by various factors that result in incorrect assessment of AEDs therapeutic equivalence and interchangeability.
Applicability of Capillary Gas-Liquid Chromatography for Determination of Parabens in Pharmaceutical Analysis
Authors: Ioutsi A. N. , Sumtsov M. A. , Artyushenko D. A. , Bychenkov D. V. , Blinov A. N.
Published: June 2019

The traditional gas-liquid chromatography (GLC) method using packed columns is still used in pharmaceutical analysis for determination of parabens, despite the fact that this technique has a number of serious drawbacks.

The aim of the study was to develop a more effective capillary GLC method for determination of parabens in active pharmaceutical ingredients and finished pharmaceutical products.

Materials and methods: the study was performed using Agilent 6890N and Agilent 7890B systems with flame-ionisation detectors. The systems were equipped with Agilent 7683B and Agilent G4513A autosamplers, respectively. The following columns were used in the study: ZB-1 15 m х 0.32 mm х 0.25 pm, DB-1 30 m х 0.32 mm х 3.0 pm, Cp-Sil 5-CB 30 m х 0.32 mm х 3.0 pm.

Results: the authors developed a method for methylparaben and propylparaben determination using capillary column GLC. The chromatographic parameters (chromatographic system performance, reproducibility of peak areas, peak asymmetry) were determined for both capillary and packed column GLC. The authors outlined the prospects for simultaneous determination of several compounds using the proposed method: a four-component mixture containing methyl-, ethyl-, propyl-, and butylparaben was separated in 9 minutes. The authors used Loma Lux Psoriasis to perform partial validation of the test method. They determined the linearity range and the limit of quantitation for methylparaben and propylparaben, and verified accuracy and intermediate precision of the test method.

Conclusions: the results of the study allowed for selection of optimal chromatographic conditions for rapid and high-precision determination of methylparaben and propylparaben in medicinal products. The developed method is recommended for control of the content of these compounds in medicinal products.
Development of a New Dosage Form of Herbal Medicinal Products
Authors: Rukavitsyna N. P. , Sakanyan E. I. , Evdokimova O. V.
Published: June 2019

The «cut-and-pressed granules» dosage form was developed to improve the technological properties of cut and powdered herbal substances in order to compensate for their insufficient flowability, as well as to facilitate dosing, reduce the contamination of the production equipment with dust and contamination of water extracts with dietary fibers. Based on the results of the information research the authors chose an optimal technology for the production of cut-and-pressed granules from some types of herbal substances (Rose hips, Bearberry leaf, Thyme herb, Melissa herb, Oregano herb, Motherwort grass, Matricaria flower). The authors standardised the new dosage form, developed the list of test parameters, test methods, and regulatory requirements for the quality of medicinal products based on the technological features of the new dosage form. Cut-and-pressed granules should not be produced from herbal substances that contain essential oils and coumarins, as it was demonstrated that the content of these compounds may decrease in the process of wet granulation. To determine whether it is possible to produce cut-and-pressed granules from a particular type of raw material, it is necessary to conduct comparative experimental studies confirming that the quality of aqueous extracts obtained from powdered herbal substances in sachets is comparable to that of tinctures or decoctions obtained from cut-and-pressed granules packed in sachets. The materials of the study were used to draft the general chapter OFS.1.4.1.0022.15 «Cut-and-pressed granules». This dosage form is not described in any foreign pharmacopoeias.
Боронование зубовыми боронами как агроприем
Authors: Тупицын Николай Васильевич , Тупицын Василий Николаевич , Егоров Сергей Николаевич
Published: June 2019

Приведен аналитический обзор использования зубовых борон в различных технологических процессах. Представлены описание новой конструкции бороны и особенности ее использования. Положительной особенностью использования борон со скользяще-режущим принципом работы зубьев являлось меньшее усилие трактора. Разница в усилии на крюке составила 12 %. Опытный вариант борон обеспечил более щадящий для растений озимой пшеницы режим работы. Растения в меньшей степени, чем на контроле, приваливались почвой и вырывались с корнем. Различия по количеству приваленных растений в ходе боронования между опытным вариантом и контролем составили 70,5 шт./м2, а по количеству выдернутых полностью растений — 21,4 шт./м2. Конструкция зуба бороны в форме эллипса со скользяще-режущими принципом работы позволяет, по сравнению с прототипом, получать следующие преимущества: уменьшить усилие трактора на крюке, мельче крошить почву, меньше забиваться соломой и растительными остатками, меньше выдергивать и приваливать почвой культурные растения при бороновании.
Экстерьерно-конституциональные особенности и взаимосвязь фенотипических признаков у скота герефордской породы забайкальской и канадской селекций
Authors: Хамируев Тимур Николаевич
Published: June 2019

Современное развитие племенного мясного скотоводства предъявляет повышенные требования к показателям роста и развития животных. Исследования проводили в племенном репродукторе Забайкальского края на мясных коровах герефордской породы забайкальской и канадской селекций в возрасте 5 лет. Коровы из Канады превосходили аналогов местной селекции по живой массе на 1,5 % и отличались лучшими показателями высотных промеров статей тела — 3,8 – 6,5 % (p < 0,05; p < 0,001), косой длины туловища — 2,6 %, зада — 3,1 %. Коровы забайкальской селекции выделялись промерами, характеризующими развитие грудной части тела (по ширине груди +14,2 %, p < 0,001; обхвату груди +1,8 %). Расчет индексов телосложения указывает на то, что забайкальские коровы более массивные, сбитые и широкотелые, превосходство составляет 5,7 % (p < 0,001), 4,5 (p < 0,05) и 12,6 % (p < 0,001) соответственно, тогда как канадские сверстницы отличаются длинноногостью — +9,0 % (p < 0,01). Тесная положительная корреляция установлена между живой массой и обхватом груди у коров обеих групп (r = 0,907; 0,708), а также с высотными промерами и глубиной и шириной груди. Отмечена отрицательная корреляционная взаимосвязь живой массы с шириной тела в маклоках. Наиболее значительная связь у подопытного скота выявлена между живой массой и индексом сбитости — r = 0,247 – 0,399, отрицательная — между живой массой и длинноногостью. Полученные результаты необходимо использовать в дальнейшей селекционно-племенной работе по совершенствованию крупного рогатого скота герефордской породы с использованием генофонда канадской селекции.
Study the Effect of Counseling on Early Initiation of Breastfeeding with Media Breastfeeding E-books
Authors: Rahmawati Elsa Budi Sihsilya , Saputri Poppy Farantia
Published: June 2019

Early Initiation of Breastfeeding (EIBF) is the first step in the success of a baby to learn to suckle first early after birth. The coverage of EIBF is still very low in 2010 (29.3%) and in 2013 it became (34.5%). This study aims to analyze the influence of Successful Breastfeeding e-book on the Practice EIBF. The research design used a quasi experiment design with pre-post-test control group design. The study was conducted on 54 pregnant women 3rd trimester with purposive sampling method (March-June 2018). Data analysis used an independent t-test and Chi square test. The results showed that there was an effect of e-book on knowledge of pregnant women (p value 0.00). Counseling with Successful Breastfeeding e-books affects the Practice of EIBF (p value 0.017). A commitment is needed from health workers, especially those related to pregnant women and giving birth to provide counseling related to the importance of EIBF.
Community Based Breastfeeding Counseling for Succesfull Exclusive Breastfeeding
Authors: Rahayu Dwi , Yunarsih Yunarsih
Published: June 2019

Maternal problems during the postpartum are physiological and psychological changes. The postpartum period is a critical moment for mother to adapt after childbirth. Adaptations include adjusting to the partner and building positive interactions with the baby. Tthe problems that occurred during the postpartum period was the fail in giving exclusive breastfeeding. The purpose of this study is to prove the influence of Community Based Breastfeeding Counseling on the success of exclusive breastfeeding.The research design used pre experimental design with one group pre-post test design approach. The respondents are Pospartum Primipara. Data collection with questionnaire for the success of Exclusive Breastfeeding. Data analysis using Chi-Square with significance level α = 0.05 obtained result x2 = 0,000 and coefficient contingency = 0.707 means there is a difference between Practice of exclusive breastfeeding before and after  Community Based Breastfeeding Counseling means there is influence of Community Based Breastfeeding Counseling for Successful Exclusive breastfeeding.
Correlation Between an Exclusive Breast Feeding with Baby’s Nutritional Status Assessed at Primary Health Care, Region I in North Denpasar
Authors: Novi Ekajayanti Pande Putu , Indah Purnamayanthi Pande Putu
Published: June 2019

According to data from the Basic Health Research of Indonesia (Riskesdas), exclusively breastfed babies has reached only 15.3% in 2010. While in Denpasar, its level fell from 62.2% in 2007 to 56.2% in 2008 for infants aged 0-6 months. This study aims to find out an exclusive breastfeeding given in infants, assessing infant’s nutritional status, and the correlation between an exclusive breastfeeding with infant’s nutritional status at Primary Health Care, Region I in North Denpasar. This research used a descriptive correlative method. Subjects were given exclusively breastfed for totally 45 respondents. This type of sampling using a purposive sampling. Statistical analysis was done by Chi-Square. Respondents were breastfed exclusively has higher normal nutritional status for about 51.1% compared with those whose was not given, showing only 15.6%.
A Systematic Review of Teacher–Child Interactions With Multilingual Young Children
Authors: Langeloo Annegien , Mascareño Lara Mayra , Deunk Marjolein I. , Klitzing Nikolai F. , Strijbos Jan-Willem
Published: June 2019

Teacher–child interactions are the most important factor that determines the quality of early-childhood education. A systematic review was conducted to gain a better understanding of the nature of teacher–child interactions that multilingual children are exposed to, and of how they differ from teacher–child interactions of monolingual children. Thirty-one studies were included. The included studies (a) mainly focused on multilingual children with low language proficiency in the majority language and (b) hardly compared between monolingual and multilingual children. The review shows that teacher–child interactions of multilingual children are comparable to the interactions of monolingual children, although teachers do adopt different strategies to facilitate the development of multilingual children, such as the use of the home language and nonverbal communication to support understanding. Worryingly, several studies indicate that multilingual children are exposed to unequal learning opportunities compared with their monolingual peers.
Marriage Penalty: Unconditional Quantile Regression of Housework Participation in Japan
Authors: Kolpashnikova Kamila , Kan Man-Yee , Shirakawa Kiyomi
Published: June 2019

We analyze cross-sectional time-use diaries from the 2011 and 2016 Survey on Time Use and Leisure Activities (Shakai Seikatsu Kihon Chosa) to investigate the association between educational level and housework participation at different quantiles. Using the unconditional quantile regression method, we test whether education is associated with less time spent on housework as the previous research on highly educated people suggests. We find that this hypothesis stands only for non-married Japanese women. On the other hand, among married Japanese women, especially those without children in higher deciles of housework participation, are more likely to increase their participation in housework with the increase in their educational level. The results suggest that in Japan, the institute of marriage places higher expectations on women’s housework participation on married women with higher levels of education.
Data Prognostics Using Symbolic Regression
Authors: Adams Van Hunter
Published: June 2019

This paper describes a general technique for data prognostics using symbolic regression. This analysis treats the characterization of turbofan engine degradation as a particular application for the general technique. The proposed genetic program (GP) characterizes engine degradation, and then uses that characterization to both detect engine faults and predict the remaining lifetimes of engines after a fault. The genetic program exploits the fact that engine degradation manifests itself as changing correlations between sensor outputs. The NASA Prognostics Data Repository provides a training set in which 100 simulated engines are run to failure, and a test set in which a separate set of 100 simulated engines are shut off before they fail. The GP uses the training fleet of engines to identify the sensor relationships that indicate engine fault and predict remaining lifetime, and then observes the learned sensor relationships in the test fleet. The genetic program successfully detects the moment that the fault occurs for every engine in the test fleet and accurately predicts the remaining lifetime of the engines after the fault.
6 Pelajaran Manajemen SDM yang Perlu Diimplementasikan
Authors: Munawwaroh Roudhotul
Published: June 2019

6 Pelajaran Manajemen SDM yang Perlu Diimplementasikan berisi Perluas Keahlian Anda, Bantu Anggota Tim SDM Melihat Nilai Kontribusi Mereka, Memimpin dengan Tauladan Contoh
Peranan Musik bagi Perkembangan Panggilan Para Seminaris di Seminari Menengah Stella Maris Bogor
Authors: Situmorang Dominikus David Biondi
Published: June 2019

Karya tulis ini disusun guna memenuhi salah satu persyaratan menempuh Ujian Akhir pada bidang studi Bahasa Indonesia dan Pendidikan Agama Katolik, Tahun Ajaran 2005/2006. Disusun oleh Dominikus David Biondi Situmorang, III IPS 5 (0304.1.073).
Powerlessness and Unfairness
Authors: Vogt Henri
Published: June 2019

Jan Zielonka’s Counter-Revolution: Liberal Europe in Retreat (Oxford University Press, 2018) is a furious, worried pamphlet on the challenges that European democracies are currently facing, on the apparent rise of illiberalism. This article critically reviews the book and seeks to offer a somewhat different and perhaps more optimistic picture of the current predicaments of European politics. The main point of reference in this respect is Finland, a country whose political institutions have managed, by and large, to uphold a sense of coherence in society. A commitment to participatory, equality-based, and freedom-generating institutions can indeed be seen as a primary means to counter the decline of liberalism.
Garry Rodan, Participation Without Democracy
Authors: Ordoñez Matthew David
Published: June 2019

Garry Rodan, Participation Without Democracy: Containing Conflict in Southeast Asia (Ithaca and London: Cornell University Press, 2018), 281pp., ISBN: 9781501720109.
The Postwar Schoolbook as a Material Artifact
Authors: Sioki Niki
Published: June 2019

In contrast to the countries of Western Europe, the end of the Second
World War did not bring political restoration, economic recovery, or the emergence of a new social order to Greece. Subscribing to the view that the material form of books and their typography convey meaning, this article presents a comparative study of the design and production of a reading primer and a third-year reading textbook, both of which were published in a climate of political and social disorder. Drawing on surviving copies of the books, educational laws, teachers’ recollections, and archival material, this article examines the ways in which the sociopolitical environment and technological conditions of a publication affect the ways in which texts are shaped into book form.
How to find the right job or, at least, avoid the failure of choosing the wrong one
Authors: Bissels Gerhard
Published: June 2019

This paper aims to help medical librarians spot potential friction with a would-be employer. This is achieved by naming the most important aspects to focus on while choosing a new position, in order to avoid disappointment in a new role. It summarises anecdotal evidence based on personal experience.