bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods and Table 1 from Phase I Study of Topotecan, Ifosfamide, and Etoposide (TIME) with Autologous Stem Cell Transplant in Refractory Cancer: Pharmacokinetic and Pharmacodynamic Correlates
Authors: Perkins Janelle B. , Goldstein Steven C. , Dawson Jana L. , Kim Jongphil , Field Teresa L. , Partyka James S. , Fields Karen K. , Maddox Beth L. , Simonelli Christine E. , Neuger Anthony M. , Lush Richard M. , Sullivan Daniel M.
Published: April 2023

PDF file - 64K
Supplementary Figure Legends from Leukemia Cell-Rhabdovirus Vaccine: Personalized Immunotherapy for Acute Lymphoblastic Leukemia
Authors: Conrad David P. , Tsang Jovian , Maclean Meaghan , Diallo Jean-Simon , Le Boeuf Fabrice , Lemay Chantal G. , Falls Theresa J. , Parato Kelley A. , Bell John C. , Atkins Harold L.
Published: April 2023

Supplementary Figure Legends - PDF file 75K, Legends for Supplemental Figures S1 - S7
Supplementary Methods from miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways
Authors: Majid Shahana , Dar Altaf A. , Saini Sharanjot , Shahryari Varahram , Arora Sumit , Zaman Mohd Saif , Chang Inik , Yamamura Soichiro , Tanaka Yuichiro , Chiyomaru Takeshi , Deng Guoren , Dahiya Rajvir
Published: April 2023

PDF file - 93K
Supplementary Materials and Methods and Figures from Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma
Authors: Zheng Longyi , Yang Wen , Wu Fuquan , Wang Chao , Yu Lexing , Tang Liang , Qiu Bijun , Li Yuqiong , Guo Linna , Wu Mengchao , Feng Gensheng , Zou Dajin , Wang Hongyang
Published: April 2023

PDF file, 983K, Supplemental Figure S1 p-AMPK/AMPK ratios of 19 HCC specimens. Supplemental Figure S2 Western blot analysis of p-AMPK(Thr172), PARP, CyclinD1. Supplemental Figure S3 AICAR inhibits human HCC cells growth. Supplemental Figure S4 Transfection of siRNA target AMPKalpha1 and AMPKalpha2 effectively knockdown expression of AMPK in SMMC7721 cells. Supplemental Figure S5 Metformin inhibits HCC cells growth via activation of AMPK. Supplemental Figure S6 Metformin causes cycle arrest and induces apoptosis in HCC cells. Supplemental Figure S7 Therapeutic metformin/AMPK activation sensitizes HCC cells towards chemotherapy. Supplemental Figure S8 Therapeutic metformin/AMPK activation inhibited IL-6/STAT3 signaling activity Supplemental Figure S9 Correlation between expression of p-AMPK (Thr172) and P65 nuclear staining in human HCC specimens. Supplemental Figure S10 AICAR treatment repressed NF-kappaB reporter gene activity. Supplemental Figure S11 SMMC7721 or HepG2 cells were transfected with vector, IkappaBalpha superrepressor (IkappaBalphaSR) or P65. Supplemental Figure S12 IkappaBalphaSR prevented metformin-induced upregulation of PTEN expression in SMMC7721 cells Supplemental Figure S13 Metformin did not significantly affect body weight, average blood glucose level and liver function of the mice. Supplemental Figure S14 Western blot analysis on the expressions of p-AMPK, p-PTEN, PTEN, p-STAT3 and STAT3 from respective cell homogenate Supplemental Table S1 Primer Sequences Used for RT-PCR.
Supplementary Figure 5 from Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase Expression
Authors: Contractor Kaiyumars , Challapalli Amarnath , Barwick Tara , Winkler Mathias , Hellawell Giles , Hazell Steve , Tomasi Giampaolo , Al-Nahhas Adil , Mapelli Paola , Kenny Laura M. , Tadrous Paul , Coombes R. Charles , Aboagye Eric O. , Mangar Stephen
Published: April 2023

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Supplementary Figure S1 from Poor Concordance among Nine Immunohistochemistry Classifiers of Cell-of-Origin for Diffuse Large B-Cell Lymphoma: Implications for Therapeutic Strategies
Authors: Coutinho Rita , Clear Andrew James , Owen Andrew , Wilson Andrew , Matthews Janet , Lee Abigail , Alvarez Rute , da Silva Maria Gomes , Cabeçadas José , Calaminici Maria , Gribben John G.
Published: April 2023

PDF file 265K, Supplementary Figure 1: Immunohistochemistry results for each antibody (A) BCL2; (B) CD10; (C) MUM1; (D) LMO2; (E) GCET1; (F) BCL6; (G) FOXP1. Original magnification: x20
Supplementary Table 3 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 62K, Adverse reactions of all CGTG-102 patients.
Supplementary Figure 5 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 141K, Example of progressive inflammation in serial treatment.
Supplementary Figure 2 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 100K, PBMCs were isolated from patients before and circa one month after treatment and pulsed with an adenovirus-derived peptide pool and analyzed with IFN-gamma ELISPOT.
Supplementary Table 1 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 81KB, Kinetic and Equilibrium binding constants, determined by surface plasmon resonance, for binding of murine BRCA84D, RES240 and MGA271 to human and cynomolgus monkey B7-H3.
Supplemental Figure 4 from Anticancer Effects of Niclosamide in Human Glioblastoma
Authors: Wieland Anja , Trageser Daniel , Gogolok Sabine , Reinartz Roman , Höfer Heike , Keller Mihaela , Leinhaas Anke , Schelle Ramona , Normann Sabine , Klaas Lil , Waha Andreas , Koch Philipp , Fimmers Rolf , Pietsch Torsten , Yachnis Anthony T. , Pincus David W. , Steindler Dennis A. , Brüstle Oliver , Simon Matthias , Glas Martin , Scheffler Björn
Published: April 2023

Full-length blots presented in this study.
Supplementary Figure 4 from Spleen Cells from Young but Not Old Immunized Mice Eradicate Large Established Cancers
Authors: Schreiber Karin , Arina Ainhoa , Engels Boris , Spiotto Michael T. , Sidney John , Sette Alessandro , Karrison Theodore G. , Weichselbaum Ralph R. , Rowley Donald A. , Schreiber Hans
Published: April 2023

PDF file, 33KB, Percentages and absolute numbers of regulatory CD4+ T cells (Treg) in the peripheral blood of young (5 month-old) and old (15 monthold) mice.
CCR Translation for This Article from A Phase I Trial and Pharmacokinetic Study of Aflibercept (VEGF Trap) in Children with Refractory Solid Tumors: A Children's Oncology Group Phase I Consortium Report
Authors: Bender Julia Glade , Blaney Susan M. , Borinstein Scott , Reid Joel M. , Baruchel Sylvain , Ahern Charlotte , Ingle Ashish M. , Yamashiro Darrell J. , Chen Alice , Weigel Brenda , Adamson Peter C. , Park Julie R.
Published: April 2023

CCR Translation for This Article from A Phase I Trial and Pharmacokinetic Study of Aflibercept (VEGF Trap) in Children with Refractory Solid Tumors: A Children's Oncology Group Phase I Consortium Report
Supplemental Material Section S7 from miRNA Landscape in Stage I Epithelial Ovarian Cancer Defines the Histotype Specificities
Authors: Calura Enrica , Fruscio Robert , Paracchini Lara , Bignotti Eliana , Ravaggi Antonella , Martini Paolo , Sales Gabriele , Beltrame Luca , Clivio Luca , Ceppi Lorenzo , Di Marino Mariacristina , Fuso Nerini Ilaria , Zanotti Laura , Cavalieri Duccio , Cattoretti Giorgio , Perego Patrizia , Milani Rodolfo , Katsaros Dionyssios , Tognon Germana , Sartori Enrico , Pecorelli Sergio , Mangioni Costantino , D'Incalci Maurizio , Romualdi Chiara , Marchini Sergio
Published: April 2023

PDF file - 330K, The clinical stratification of the 76 selected patients used for the integrative analysis and the MAGIA2 complete results.
Supplemental Material Section S4 from miRNA Landscape in Stage I Epithelial Ovarian Cancer Defines the Histotype Specificities
Authors: Calura Enrica , Fruscio Robert , Paracchini Lara , Bignotti Eliana , Ravaggi Antonella , Martini Paolo , Sales Gabriele , Beltrame Luca , Clivio Luca , Ceppi Lorenzo , Di Marino Mariacristina , Fuso Nerini Ilaria , Zanotti Laura , Cavalieri Duccio , Cattoretti Giorgio , Perego Patrizia , Milani Rodolfo , Katsaros Dionyssios , Tognon Germana , Sartori Enrico , Pecorelli Sergio , Mangioni Costantino , D'Incalci Maurizio , Romualdi Chiara , Marchini Sergio
Published: April 2023

PDF file - 176K, miRNA expression analysis methodology, the complete lists of differentially expressed genes for each subtype comparison and the relative resampling score.
Supplementary Figures 1-3 from Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Posttransplant Lymphoproliferative Disorders: Implications for Targeted Therapy
Authors: Green Michael R. , Rodig Scott , Juszczynski Przemyslaw , Ouyang Jing , Sinha Papiya , O'Donnell Evan , Neuberg Donna , Shipp Margaret A.
Published: April 2023

PDF file - 238K, Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Post-transplant Lymphoproliferative Disorders: Implications for Targeted Therapy.
Supplementary Table 6 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

XLS file 38K, Single-biomarker tumor growth inhibition projection
Supplementary Table 3 from Characterization of Gene Amplification–Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics
Authors: Li Chien-Feng , Wang Ju-Ming , Kang Hong-Yo , Huang Chiung-Kuei , Wang Jun-Wen , Fang Fu-Min , Wang Yu-Hui , Wu Wen-Ren , Li Shau-Hsuan , Yu Shih-Chen , Lee Jen-Chieh , Lan Jui , Shiue Yow-Ling , Wu Li-Ching , Huang Hsuan-Ying
Published: April 2023

PDF file - 142K
Supplementary Table 4 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

PDF file 161K, Tumor PIK3CA and PTEN status
Supplementary Figure 6 from Characterization of Gene Amplification–Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics
Authors: Li Chien-Feng , Wang Ju-Ming , Kang Hong-Yo , Huang Chiung-Kuei , Wang Jun-Wen , Fang Fu-Min , Wang Yu-Hui , Wu Wen-Ren , Li Shau-Hsuan , Yu Shih-Chen , Lee Jen-Chieh , Lan Jui , Shiue Yow-Ling , Wu Li-Ching , Huang Hsuan-Ying
Published: April 2023

PDF file - 116K, Left panel: There is no significant body weight loss in the bortezomib-treated NMFH-1-xenografted mice. Right panel: Compared to the vehicle control group, no apparent impairment of hepatic and renal function is seen in the xenografted mice treated with bortezomib by measuring serum AST, ALT and BUN, creatinine, respectively.
Supplementary Table 2 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

XLS file 38K, The ten core biomarkers p-values
Supplementary Figure 3 from In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate
Authors: Chuang Chih-Hung , Chuang Kuo-Hsiang , Wang Hsin-Ell , Roffler Steve R. , Shiea Jen-taie , Tzou Shey-Cherng , Cheng Ta-Chun , Kao Chien-Han , Wu Shih-Yen , Tseng Wei-Lung , Cheng Chiu-Min , Hou Ming-Feng , Wang Ju-Ming , Cheng Tian-Lu
Published: April 2023

PDF file - 1.3MB
Supplementary Figure 2 from Phase I Trial of a Glypican-3–Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival
Authors: Sawada Yu , Yoshikawa Toshiaki , Nobuoka Daisuke , Shirakawa Hirofumi , Kuronuma Toshimitsu , Motomura Yutaka , Mizuno Shoichi , Ishii Hiroshi , Nakachi Kohei , Konishi Masaru , Nakagohri Toshio , Takahashi Shinichiro , Gotohda Naoto , Takayama Tadatoshi , Yamao Kenji , Uesaka Katsuhiko , Furuse Junji , Kinoshita Taira , Nakatsura Tetsuya
Published: April 2023

PDF file, 36KB, A 30 mg dose of peptide caused stronger local skin reactions (blushing, induration) at the injection site than did a 3.0 mg dose.
Table S1 from A Novel Engineered Anti-CD20 Tracer Enables Early Time PET Imaging in a Humanized Transgenic Mouse Model of B-cell Non-Hodgkins Lymphoma
Authors: Natarajan Arutselvan , Hackel Benjamin J. , Gambhir Sanjiv Sam
Published: April 2023

PDF file 56K, Organs uptake presented in the table were mean {plus-minus} SD {percent}ID/g measured by either ROI (Fig. S1) or by ex vivo weighing (Bio) sacrificed after 24h p.i and counting the tissues in gamma counter. L= Liver, K= Kidney, BP = blood pool, and arrow = tumor. ND: not detected. T: O = tumor to organ ratio liver, kidney and spleen
Supplementary Figure Legend from A Novel Engineered Anti-CD20 Tracer Enables Early Time PET Imaging in a Humanized Transgenic Mouse Model of B-cell Non-Hodgkins Lymphoma
Authors: Natarajan Arutselvan , Hackel Benjamin J. , Gambhir Sanjiv Sam
Published: April 2023

PDF file 72K, MicroPET images are Ramos CD20 (+) tumor bearing mice (n= 3) administered with 64Cu-Do-FN3CD20 (A) and 64Cu-Do-rituximab (B) tracers. Coronal images of PET were acquired after 4h and 24h (PET/CT) p.i
Supplementary Figure Legend from Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma
Authors: Takahashi Yoko , Kupferman Michael E. , Bell Diana , Jiffar Tilahun , Lee June Goo , Xie Tong-Xin , Li Ning-Wei , Zhao Mei , Frederick Mitchell J. , Gelbard Alexander , Myers Jeffrey N. , Hanna Ehab Y.
Published: April 2023

PDF file - 104K
Supplementary Figure 4 from Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma
Authors: Takahashi Yoko , Kupferman Michael E. , Bell Diana , Jiffar Tilahun , Lee June Goo , Xie Tong-Xin , Li Ning-Wei , Zhao Mei , Frederick Mitchell J. , Gelbard Alexander , Myers Jeffrey N. , Hanna Ehab Y.
Published: April 2023

PDF file - 157K, Expression pattern of epithelial-mesenchymal transition markers in early and late passage SNUC cells. Expression pattern of epithelial markers (pan-keratin and E-cadherin) and mesenchymal markers (α-SMA and vimentin) in both early (at passage number 17 in MDA8788-6 and at passage number 15 in MDA8788-7) and late passage (at passage number 40) in the SNUC cells was analyzed by Western blotting. Both early and late passage of SNUC cells expressed only the epithelial markers and did not expressed mesenchymal markers.
Supplementary Figure 1 from Scatter Spectroscopic Imaging Distinguishes between Breast Pathologies in Tissues Relevant to Surgical Margin Assessment
Authors: Laughney Ashley M. , Krishnaswamy Venkataramanan , Rizzo Elizabeth J. , Schwab Mary C. , Barth Richard J. , Pogue Brian W. , Paulsen Keith D. , Wells Wendy A.
Published: April 2023

PDF file, 133K, Box plots of textural features as a function of diagnosis.
Supplementary Table 1 from Circulating Tumor Cells in Patients with Testicular Germ Cell Tumors
Authors: Nastały Paulina , Ruf Christian , Becker Pascal , Bednarz-Knoll Natalia , Stoupiec Małgorzata , Kavsur Refik , Isbarn Hendrik , Matthies Cord , Wagner Walter , Höppner Dirk , Fisch Margit , Bokemeyer Carsten , Ahyai Sascha , Honecker Friedemann , Riethdorf Sabine , Pantel Klaus
Published: April 2023

PDF file - 65KB, Characterization of relapsed, treatment-refractory germ cell tumor patients.
Supplementary Figure 1 from Circulating Tumor Cells in Patients with Testicular Germ Cell Tumors
Authors: Nastały Paulina , Ruf Christian , Becker Pascal , Bednarz-Knoll Natalia , Stoupiec Małgorzata , Kavsur Refik , Isbarn Hendrik , Matthies Cord , Wagner Walter , Höppner Dirk , Fisch Margit , Bokemeyer Carsten , Ahyai Sascha , Honecker Friedemann , Riethdorf Sabine , Pantel Klaus
Published: April 2023

PDF file - 209KB, Positivity for SALL4, OCT3/4, keratins, EpCAM and Cellsearch(registered trademark) assay in control cell lines. A, Double fluorescence staining for SALL4 (green) / keratins (orange) and OCT3/4 (green) / EpCAM (orange) counterstained with DAPI (blue) to visualize cells' nuclei in 4 different germ cell tumor cell lines (magnification: 400x). Scale bar, 50 microm. B, Representation of the staining of tumor cells from 4 different germ cell tumor cell lines spiked into blood of healthy donors using the Cellsearch(registered trademark) assay. C, Representative images of primary testicular germ cell tumor samples positive for SALL4, OCT3/4, keratins and EpCAM immunohistochemical staining counterstained with Hematoxylin to visualize cells' nuclei (magnification - 400x, scale bar - 50 microm). (CK, cytokeratin. PE, phycoerythrin. APC, allophycocyanin. DAPI, 4′,6-diamidino-2-phenylindole). D, Dot-like pattern keratin (orange) staining in TCam-2 and NT2 cell lines, counterstained with DAPI (blue) to visualize cells' nuclei (magnification: 1000x). Scale bar, 20 microm.
Supplementary Table 1 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 80K, Integrin β1 knock-down did not affected cell proliferation.
Supplementary Table 2 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 105K, Table S2. Association between MDA-9/Syntenin, EGFR, c-Src, AKT, CTNNB1 and E-cadherin expression and different clinical characteristics
Supplementary Figure 1 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 346K, DFS and OS analysis between patients with and without metastasis.
Supplementary Figure 7 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 154K, Supplementary Figure S7: Progressive increase of MDA-9 mRNA from normal urothelium to CIS to muscle-invasive cancer was evident in datasets available in Gene Expression Omnibus database (GEO # GSE 3167)
Supplementary Figure Legend from Chromosome 5q Loss in Colorectal Flat Adenomas
Authors: Voorham Quirinus J.M. , Carvalho Beatriz , Spiertz Angela J. , van Grieken Nicole C.T. , Mongera Sandra , Rondagh Eveline J.A. , van de Wiel Mark A. , Jordanova Ekaterina S. , Ylstra Bauke , Kliment Martin , Grabsch Heike , Rembacken Bjorn J. , Arai Tomio , de Bruïne Adriaan P. , Sanduleanu Silvia , Quirke Philip , Mulder Chris J.J. , van Engeland Manon , Meijer Gerrit A.
Published: April 2023

PDF file, 67K.
Supplementary Figure 1 from Chromosome 5q Loss in Colorectal Flat Adenomas
Authors: Voorham Quirinus J.M. , Carvalho Beatriz , Spiertz Angela J. , van Grieken Nicole C.T. , Mongera Sandra , Rondagh Eveline J.A. , van de Wiel Mark A. , Jordanova Ekaterina S. , Ylstra Bauke , Kliment Martin , Grabsch Heike , Rembacken Bjorn J. , Arai Tomio , de Bruïne Adriaan P. , Sanduleanu Silvia , Quirke Philip , Mulder Chris J.J. , van Engeland Manon , Meijer Gerrit A.
Published: April 2023

PDF file, 464K, Concept of colorectal carcinogenesis and histological images of adenomas.
Supplementary Figure 1 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 142K, Supplementary Figure S1: A: Expression of MDA-9/Syntenin in non-tumorigenic HUC-1 cells is low or undetectable compared to the tumorigenic and aggressive T24 cells. B: Exogenously overexpressed MYC-tagged MDA-9/Syntenin expression was detectable in different clones. beta-actin was used as a loading control
Supplementary Figure 5 from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 51K, Fold change in mutation (%) frequency for 3p TSGs by size (TCGA).
Supplementary Figure 4 from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 111K, TCGA mutation combination cancer specific survival curves.
Supplementary Figure 2 from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
Authors: Hutchinson Katherine E. , Lipson Doron , Stephens Philip J. , Otto Geoff , Lehmann Brian D. , Lyle Pamela L. , Vnencak-Jones Cindy L. , Ross Jeffrey S. , Pietenpol Jennifer A. , Sosman Jeffrey A. , Puzanov Igor , Miller Vincent A. , Pao William
Published: April 2023

PDF file - 190K, Supplementary Figure S2. Detection of TRIM24-BRAF by FoundationOne(TM).
Supplementary Methods, Figure 1 from Antitumor Activity of NVP-BKM120—A Selective Pan Class I PI3 Kinase Inhibitor Showed Differential Forms of Cell Death Based on p53 Status of Glioma Cells
Authors: Koul Dimpy , Fu Jun , Shen Ruijun , LaFortune Tiffany A. , Wang Shuzhen , Tiao Ningyi , Kim Yong-Wan , Liu Juinn-Lin , Ramnarian Deepti , Yuan Ying , Garcia-Echevrria Carlos , Maira Sauveur-Michel , Yung W.K. Alfred
Published: April 2023

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Supplementary Table 1 from Tivantinib (ARQ197) Displays Cytotoxic Activity That Is Independent of Its Ability to Bind MET
Authors: Basilico Cristina , Pennacchietti Selma , Vigna Elisa , Chiriaco Cristina , Arena Sabrina , Bardelli Alberto , Valdembri Donatella , Serini Guido , Michieli Paolo
Published: April 2023

PDF File - 61K, Drugs used in this study.
Supplementary Figure Legends, Tables 1 - 3 from Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2–Negative Feedback Loop Mechanism
Authors: Lu Yan-Xia , Yuan Li , Xue Xiao-Lei , Zhou Min , Liu Yan , Zhang Chao , Li Jing-Ping , Zheng Lin , Hong Min , Li Xue-Nong
Published: April 2023

PDF file - 148KB, Aupplementary tables 1-3. S1. Primer Sequences for qRT-PCR analyses. S2. Primer Sequences used for PCR amplification of plasmid construction. S3. Clinicopathologic Characteristics of miR-200c Expression in CRC Patients.
Supplementary Table 1 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 77K, CONSORT diagram.
Supplementary Figure 1 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 57K, Quality control profiles of the samples.
Supplementary Tables 1 - 2 from Evaluation of Utility of Pharmacokinetic Studies in Phase I Trials of Two Oncology Drugs
Authors: Wu Kehua , House Larry , Ramírez Jacqueline , Seminerio Michael J. , Ratain Mark J.
Published: April 2023

PDF file - 134K, Table S1. Data collection form. Table S2. Collected data.
Supplementary Figure Legend from Activity of the Hypoxia-Activated Prodrug, TH-302, in Preclinical Human Acute Myeloid Leukemia Models
Authors: Portwood Scott , Lal Deepika , Hsu Yung-Chun , Vargas Rodrigo , Johnson Megan K. , Wetzler Meir , Hart Charles P. , Wang Eunice S.
Published: April 2023

PDF file - 74K
Supplementary Figure 1 from Characteristics of Lung Cancers Harboring NRAS Mutations
Authors: Ohashi Kadoaki , Sequist Lecia V. , Arcila Maria E. , Lovly Christine M. , Chen Xi , Rudin Charles M. , Moran Teresa , Camidge David Ross , Vnencak-Jones Cindy L. , Berry Lynne , Pan Yumei , Sasaki Hidefumi , Engelman Jeffrey A. , Garon Edward B. , Dubinett Steven M. , Franklin Wilbur A. , Riely Gregory J. , Sos Martin L. , Kris Mark G. , Dias-Santagata Dora , Ladanyi Marc , Bunn Paul A. , Pao William
Published: April 2023

PDF file - 66K, Figure S1. The distribution of known driver mutations in lung cancer patients at VICC. 451 lung cancer patients were analyzed using SnaPShot.(47) Patients with ALK fusions are not shown, as they were identified using a separate cytogenetic assay (fluorescent in situ hybridization).
Supplementary Figure 1 from Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts
Authors: Allen Bryan G. , Bhatia Sudershan K. , Buatti John M. , Brandt Kristin E. , Lindholm Kaleigh E. , Button Anna M. , Szweda Luke I. , Smith Brian J. , Spitz Douglas R. , Fath Melissa A.
Published: April 2023

Supplementary Figure 1 - PDF file 911K, Mouse weights
Supplementary Figure 2 from Rb Loss Is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma
Authors: Tan Hsueh-Li , Sood Akshay , Rahimi Hameed A. , Wang Wenle , Gupta Nilesh , Hicks Jessica , Mosier Stacy , Gocke Christopher D. , Epstein Jonathan I. , Netto George J. , Liu Wennuan , Isaacs William B. , De Marzo Angelo M. , Lotan Tamara L.
Published: April 2023

PDF file - 495K, Supplementary Figure S2: (A) Validation of nanoString copy number assessment against copy number calls made using high density SNP array (Affymetrix 6.0) using 4 cases of metastatic castration resistant prostate cancer. There is a high correlation between copy number calls for PTEN on both platforms. (B) There is a similarly high correlation between copy number calls for RB1 using both platforms.
Supplementary figures 1 and 2 from Tumor Growth Rate Is an Early Indicator of Antitumor Drug Activity in Phase I Clinical Trials
Authors: Ferté Charles , Fernandez Marianna , Hollebecque Antoine , Koscielny Serge , Levy Antonin , Massard Christophe , Balheda Rastislav , Bot Brian , Gomez-Roca Carlos , Dromain Clarisse , Ammari Samy , Soria Jean-Charles
Published: April 2023

PDF file 212K, Supplementary figures 1 and 2
Supplementary Table 3 from Tumor Growth Rate Is an Early Indicator of Antitumor Drug Activity in Phase I Clinical Trials
Authors: Ferté Charles , Fernandez Marianna , Hollebecque Antoine , Koscielny Serge , Levy Antonin , Massard Christophe , Balheda Rastislav , Bot Brian , Gomez-Roca Carlos , Dromain Clarisse , Ammari Samy , Soria Jean-Charles
Published: April 2023

XLS file 31K, Multivariate linear analysis of the drecrease of TGR
Supplementary Table 1 from Tumor Growth Rate Is an Early Indicator of Antitumor Drug Activity in Phase I Clinical Trials
Authors: Ferté Charles , Fernandez Marianna , Hollebecque Antoine , Koscielny Serge , Levy Antonin , Massard Christophe , Balheda Rastislav , Bot Brian , Gomez-Roca Carlos , Dromain Clarisse , Ammari Samy , Soria Jean-Charles
Published: April 2023

XLS file 26K, Distribution of the patients according to the trial characteristics
Supplementary Results and Methods from A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer
Authors: Marin-Muller Christian , Li Dali , Bharadwaj Uddalak , Li Min , Chen Changyi , Hodges Sally E. , Fisher William E. , Mo Qianxing , Hung Mien-Chie , Yao Qizhi
Published: April 2023

Supplementary Results and Methods - PDF file 255K, Additional information on results and methods
Supplementary Table 2 from CD62L as a Therapeutic Target in Chronic Lymphocytic Leukemia
Authors: Burgess Melinda , Gill Devinder , Singhania Richa , Cheung Catherine , Chambers Lynne , Renyolds Brent A. , Smith Louise , Mollee Peter , Saunders Nicholas , McMillan Nigel AJ
Published: April 2023

Supplementary Table 2 - PDF files 77K, CD markers used in phenotype screen
Supplementary Table 1 from The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression
Authors: Salvador Marion A. , Wicinski Julien , Cabaud Olivier , Toiron Yves , Finetti Pascal , Josselin Emmanuelle , Lelièvre Hélène , Kraus-Berthier Laurence , Depil Stéphane , Bertucci François , Collette Yves , Birnbaum Daniel , Charafe-Jauffret Emmanuelle , Ginestier Christophe
Published: April 2023

PDF file 44K, Clinical and pathological features of the breast cancer cell lines (BCLs)
Supplementary Figure S1 from Inhibition of Tumor Growth and Metastasis in Non–Small Cell Lung Cancer by LY2801653, an Inhibitor of Several Oncokinases, Including MET
Authors: Wu Wenjuan , Bi Chen , Credille Kelly M. , Manro Jason R. , Peek Victoria L. , Donoho Gregory P. , Yan Lei , Wijsman John A. , Yan S. Betty , Walgren Richard A.
Published: April 2023

Supplementary Figure S1 - PDF file 157K, MET expression by immunohistochemistry
Fig. S2 from The Disparate Twins: A Comparative Study of CXCR4 and CXCR7 in SDF-1α–Induced Gene Expression, Invasion and Chemosensitivity of Colon Cancer
Authors: Heckmann Doreen , Maier Patrick , Laufs Stephanie , Li Li , Sleeman Jonathan P. , Trunk Marcus J. , Leupold Jörg H. , Wenz Frederik , Zeller W. Jens , Fruehauf Stefan , Allgayer Heike
Published: April 2023

PDF file 100K, S2: Generation of CRC cell lines with high expression of CXCR4 and/or CXCR7
Supplementary Table 7 from Busulfan in Infant to Adult Hematopoietic Cell Transplant Recipients: A Population Pharmacokinetic Model for Initial and Bayesian Dose Personalization
Authors: McCune Jeannine S. , Bemer Meagan J. , Barrett Jeffrey S. , Scott Baker K. , Gamis Alan S. , Holford Nicholas H.G.
Published: April 2023

PDF file 62K, Predicted initial IV busulfan dose for daily administration to achieve a busulfan target Css of 770 ng/mL using the normal fat mass (NFM) model
Supplementary Figure 4 from Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers
Authors: Prosniak Michael , Harshyne Larry A. , Andrews David W. , Kenyon Lawrence C. , Bedelbaeva Kamila , Apanasovich Tatiyana V. , Heber-Katz Ellen , Curtis Mark T. , Cotzia Paolo , Hooper D. Craig
Published: April 2023

PDF - 47K, Heat map representation of the expression of select genes associated with M1-M2 monocyte polarization.
Supplementary Table 1 from BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
Authors: Frederick Dennie T. , Piris Adriano , Cogdill Alexandria P. , Cooper Zachary A. , Lezcano Cecilia , Ferrone Cristina R. , Mitra Devarati , Boni Andrea , Newton Lindsay P. , Liu Chengwen , Peng Weiyi , Sullivan Ryan J. , Lawrence Donald P. , Hodi F. Stephen , Overwijk Willem W. , Lizée Gregory , Murphy George F. , Hwu Patrick , Flaherty Keith T. , Fisher David E. , Wargo Jennifer A.
Published: April 2023

PDF file - 50K, Patient Characteristics.
Supplementary Figure 1 from MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer
Authors: Yu San-Jian , Hu Jing-Ying , Kuang Xia-Ying , Luo Jian-Min , Hou Yi-Feng , Di Gen-Hong , Wu Jiong , Shen Zhen-Zhou , Song Hou-Yan , Shao Zhi-Ming
Published: April 2023

PDF file - 947K, Anoikis induced by suspension culture
Supplementary Data from Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3
Authors: Mujcic Hilda , Nagelkerke Anika , Rouschop Kasper M.A. , Chung Stephen , Chaudary Naz , Span Paul N. , Clarke Blaise , Milosevic Michael , Sykes Jenna , Hill Richard P. , Koritzinsky Marianne , Wouters Bradly G.
Published: April 2023

Supplementary Data - PDF file 113K, This file contains supplementary materials and methods, and the legends of the 14 supplementary figures. Suppl. Table 1 shows the patients characteristic from the clinical study described in main Fig 1. Suppl. Table 2 shows the relationship between LAMP3 protein expression and continuous clinical parameters, incl. HP5. Suppl. Table 3 shows the relationship between LAMP3 protein expression and categorical clinical parameters, incl. FIGO stage. Suppl. Fig 1 shows the association between LAMP3 gene copy number and LAMP3 gene expression in human cervix tumors described in main Fig 1, as well as the LAMP3 gene copy numbers in normal human cervix tissues. Suppl. Fig 2 provides in vitro evidence for the inducibility of the ME180 cancer cell line. Suppl. Fig 3 provides in vivo evidence for the metastatic capacity of the isogenic ME180 cell line, as well as its inducibility. Suppl. Fig 4 shows in vitro validation of the ME180-GADD34-C cells. Suppl. Fig 5 contains the raw data that belongs to main Fig 3C, which shows that Inhibition of UPR signaling suppresses hypoxia-induced lymph node metastasis. Suppl. Fig 6 shows the in vitro validation of ME180 LAMP3-knockdown cells. Suppl. Fig 7 shows representative images of LAMP3 expression in LAMP3 knockdown and empty vector control tumors described in main Fig 4B. Suppl. Fig 8 contains the raw data that belongs to main Fig 4C, which shows that knockdown of LAMP3 inhibits hypoxia-induced lymph node metastasis. Suppl. Fig 9 shows the human VEGF mRNA expression in ME180-GADD34-C orthotopic xenografts described in main Fig 3B. Suppl. Fig 10 shows the quantification of the microvessel density and hVEGF expression in shLAMP3 orthotopic xenografts described in main Fig 4B. Suppl. Fig 11 shows the hypoxic fraction shLAMP3 orthotopic xenografts described in main Fig 4B. Suppl. Fig 12 contains data from the soft agar colony formation assay that shows that knockdown of LAMP3 in HeLa cells inhibits colony formation. Suppl. Fig 13 is supplementary to main Fig 6B and shows that knockdown of LAMP3 in HeLa cells, just like in ME180 cells, inhibits transwell migration. Suppl. Fig 14 is supplementary to main Fig 6D and shows that knockdown of LAMP3 in Caski cells, just like in ME180 cells, inhibits wound closure in the scratch wound healing assay. This figure also shows that overexpression of LAMP3 accelerates wound closure
Supplementary Figure Legend from Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
Authors: Gadji Macoura , Adebayo Awe Julius , Rodrigues Prerana , Kumar Rajat , Houston Donald S. , Klewes Ludger , Dièye Tandakha Ndiaye , Rego Eduardo Magalhães , Passetto Roberto Falcão , de Oliveira Fábio Morato , Mai Sabine
Published: April 2023

PDF file, 54KB.
Supplementary Figure Legend from Frequent Mutational Activation of the PI3K-AKT Pathway in Trastuzumab-Resistant Breast Cancer
Authors: Chandarlapaty Sarat , Sakr Rita A. , Giri Dilip , Patil Sujata , Heguy Adriana , Morrow Monica , Modi Shanu , Norton Larry , Rosen Neal , Hudis Clifford , King Tari A.
Published: April 2023

PDF file - 66K
Supplementary Figure 5 from DNA Topoisomerase III Alpha Regulates p53-Mediated Tumor Suppression
Authors: Hsieh Mei-Yi , Fan Jia-Rong , Chang Han-Wen , Chen Hsiang-Chin , Shen Tang-Long , Teng Shu-Chun , Yeh Yen-Hsiu , Li Tsai-Kun
Published: April 2023

PDF file 3495K, Reduced expression of hTOP3alpha in renal and stomach tumor samples compared to the matched normal tissues
Supplementary Table 1 from Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer
Authors: Nawrocki Steffan T. , Kelly Kevin R. , Smith Peter G. , Espitia Claudia M. , Possemato Anthony , Beausoleil Sean A. , Milhollen Michael , Blakemore Stephen , Thomas Michael , Berger Allison , Carew Jennifer S.
Published: April 2023

PDF file - 71K, Supplemental Table 1. Proteins Altered >2-fold by Treatment with MLN4924.
Supplementary Figure 2 from Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer
Authors: Nawrocki Steffan T. , Kelly Kevin R. , Smith Peter G. , Espitia Claudia M. , Possemato Anthony , Beausoleil Sean A. , Milhollen Michael , Blakemore Stephen , Thomas Michael , Berger Allison , Carew Jennifer S.
Published: April 2023

PDF file - 3554K, Supplemental Figure 2: Effects of caspase inhibition and antioxidant treatment on MLN4924/cisplatin-induced DNA damage.
CCR Translation for This Article from Combination of Ponatinib with Hedgehog Antagonist Vismodegib for Therapy-Resistant BCR-ABL1–Positive Leukemia
Authors: Katagiri Seiichiro , Tauchi Tetsuzo , Okabe Seiichi , Minami Yosuke , Kimura Shinya , Maekawa Taira , Naoe Tomoki , Ohyashiki Kazuma
Published: April 2023

CCR Translation for This Article from Combination of Ponatinib with Hedgehog Antagonist Vismodegib for Therapy-Resistant BCR-ABL1–Positive Leukemia
Supplementary Figure 5 from Glucocorticoid Receptor Antagonism as a Novel Therapy for Triple-Negative Breast Cancer
Authors: Skor Maxwell N. , Wonder Erin L. , Kocherginsky Masha , Goyal Anju , Hall Ben A. , Cai Yi , Conzen Suzanne D.
Published: April 2023

Supplementary Figure 5 - PDF file 165K, alphaGR and DAPI analysis of MDA-MB-231 xenografts
Supplementary Figures 1 - 7 from Specific Lymphocyte Subsets Predict Response to Adoptive Cell Therapy Using Expanded Autologous Tumor-Infiltrating Lymphocytes in Metastatic Melanoma Patients
Authors: Radvanyi Laszlo G. , Bernatchez Chantale , Zhang Minying , Fox Patricia S. , Miller Priscilla , Chacon Jessica , Wu Richard , Lizee Gregory , Mahoney Sandy , Alvarado Gladys , Glass Michelle , Johnson Valen E. , McMannis John D. , Shpall Elizabeth , Prieto Victor , Papadopoulos Nicholas , Kim Kevin , Homsi Jade , Bedikian Agop , Hwu Wen-Jen , Patel Sapna , Ross Merrick I. , Lee Jeffrey E. , Gershenwald Jeffrey E. , Lucci Anthony , Royal Richard , Cormier Janice N. , Davies Michael A. , Mansaray Rahmatu , Fulbright Orenthial J. , Toth Christopher , Ramachandran Renjith , Wardell Seth , Gonzalez Audrey , Hwu Patrick
Published: April 2023

PDF file - 1856K, Fig. S1. Schema of TIL adoptive cell therapy clinical trial; Fig. S2. Recovery of total white blood cell counts (WBC), absolute lymphocyte counts (ALC), and absolute neutrophil counts (ANC) during adoptive transfer TIL therapy in 31 treated patients; Fig. S3. Durable partial response of an intrathoracic melanoma mass near the aorta and heart in one patient at 6 weeks and 18 months after TIL infusion; Figure S4. Kaplan-Meier curves of overall survival and progression-free survival for all 31 treated patients; Figure S5. Kaplan-Meier curves of landmark-based overall survival and progression-free survival for irRC responding and non-responding TIL-treated patients; Fig. S6. Change in tumor burden over the first 20-22 months following TIL transfer therapy in responders and non-responders; Fig. S7. Box and whisker plot showing that telomere length of infused TIL was not significantly different between responders and non-responders
Supplementary Table 2 from Long-Term Survival in Primary Glioblastoma With Versus Without Isocitrate Dehydrogenase Mutations
Authors: Hartmann Christian , Hentschel Bettina , Simon Matthias , Westphal Manfred , Schackert Gabriele , Tonn Jörg C. , Loeffler Markus , Reifenberger Guido , Pietsch Torsten , von Deimling Andreas , Weller Michael
Published: April 2023

Supplementary Table 2 - PDF file 53K, Individual profiles of LTS-36 patients with IDH1/2-wildtype glioblastomas
Supplementary Figure 8 from Sustained Inhibition of Receptor Tyrosine Kinases and Macrophage Depletion by PLX3397 and Rapamycin as a Potential New Approach for the Treatment of MPNSTs
Authors: Patwardhan Parag P. , Surriga Oliver , Beckman Michael J. , de Stanchina Elisa , Dematteo Ronald P. , Tap William D. , Schwartz Gary K.
Published: April 2023

PDF file - 45KB, Flow cytometric analysis of M2-like and M1-like macrophage phenotype in TAMs.
Data Supplement from An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non–Small Cell Lung Cancer
Authors: Noguchi Satoshi , Saito Akira , Horie Masafumi , Mikami Yu , Suzuki Hiroshi I. , Morishita Yasuyuki , Ohshima Mitsuhiro , Abiko Yoshimitsu , Mattsson Johanna Sofia Margareta , König Helena , Lohr Miriam , Edlund Karolina , Botling Johan , Micke Patrick , Nagase Takahide
Published: April 2023

Supplementary Figure S7. TAZ expression level is associated with EGFR-TKI sensitivity.
Supplementary Figure 2 from Functional Genomics Uncover the Biology behind the Responsiveness of Head and Neck Squamous Cell Cancer Patients to Cetuximab
Authors: Bossi Paolo , Bergamini Cristiana , Siano Marco , Cossu Rocca Maria , Sponghini Andrea P. , Favales Federica , Giannoccaro Marco , Marchesi Edoardo , Cortelazzi Barbara , Perrone Federica , Pilotti Silvana , Locati Laura D. , Licitra Lisa , Canevari Silvana , De Cecco Loris
Published: April 2023

Fig S2. Technical validation using NuGEN's Ovation System. The scatter plot shows the fold change consistency of genes differentially expressed using WG-DASL and NuGEN methods. Only 6 out of the 509 DE genes were found discordant, confirming the WG-DASL patterns. Data are plotted as log2 fold change (FC) expression long/short PFS; positive log2(FC) values stand for genes up-regulated in long-PFS cases, while negative values stand for up-regulation in short-PFS cases. Statistical significance was tested through Monte Carlo test (1000 interactions) yielding p-value<0.001.
Supplementary Table 2 from Mutation Profiling and Microsatellite Instability in Stage II and III Colon Cancer: An Assessment of Their Prognostic and Oxaliplatin Predictive Value
Authors: Gavin Patrick G. , Colangelo Linda H. , Fumagalli Debora , Tanaka Noriko , Remillard Matthew Y. , Yothers Greg , Kim Chungyeul , Taniyama Yusuke , Kim Seung Il , Choi Hyun Joo , Blackmon Nicole L. , Lipchik Corey , Petrelli Nicholas J. , O'Connell Michael J. , Wolmark Norman , Paik Soonmyung , Pogue-Geile Kay L.
Published: April 2023

PDF file - 45K, Power to detect prognostic and predictive effect for oxaliplatin
Data Supplement from Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers
Authors: Pickering Curtis R. , Zhang Jiexin , Neskey David M. , Zhao Mei , Jasser Samar A. , Wang Jiping , Ward Alexandra , Tsai C. Jillian , Ortega Alves Marcus V. , Zhou Jane H. , Drummond Jennifer , El-Naggar Adel K. , Gibbs Richard , Weinstein John N. , Wheeler David A. , Wang Jing , Frederick Mitchell J. , Myers Jeffrey N.
Published: April 2023

Supplementary Table 3. Mutations in MD Anderson cohort.
Supplementary Figure 1 from Prognostic Significance of AKT/mTOR and MAPK Pathways and Antitumor Effect of mTOR Inhibitor in NF1-Related and Sporadic Malignant Peripheral Nerve Sheath Tumors
Authors: Endo Makoto , Yamamoto Hidetaka , Setsu Nokitaka , Kohashi Kenichi , Takahashi Yusuke , Ishii Takeaki , Iida Kei-ichiro , Matsumoto Yoshihiro , Hakozaki Michiyuki , Aoki Mikiko , Iwasaki Hiroshi , Dobashi Yoh , Nishiyama Kenichi , Iwamoto Yukihide , Oda Yoshinao
Published: April 2023

PDF file - 328K, A case of MPNST (left) arising from neurofibroma (right) in patients with neurofibromatosis type 1. Most MPNST cells are positive for p-AKT, p-mTOR, p-S6RP, p-p70S6K, and p-4E-BP1. Meanwhile, most tumor cells in the neurofibroma area are negative for them. NF: neurofibroma.
supplemental figure legend from Integrated Analysis of PTEN and p4EBP1 Protein Expression as Predictors for pCR in HER2-Positive Breast Cancer
Authors: Loibl Sibylle , Darb-Esfahani Silvia , Huober Jens , Klimowicz Alexander , Furlanetto Jenny , Lederer Bianca , Hartmann Arndt , Eidtmann Holger , Pfitzner Berit , Fasching Peter A. , Tiemann Katharina , Jackisch Christian , Mehta Keyur , von Minckwitz Gunter , Untch Michael , Denkert Carsten
Published: April 2023

supplemental figure legend
Supplementary Figure 2 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Authors: Ran Long-Kuan , Chen Yong , Zhang Zhen-Zhen , Tao Na-Na , Ren Ji-Hua , Zhou Li , Tang Hua , Chen Xiang , Chen Ke , Li Wan-Yu , Huang Ai-Long , Chen Juan
Published: April 2023

SIRT6 depletion increased cell sensitivity to doxorubicin. Cells in different groups with or without doxorubicin treatment were subjected to flow cytometry with Annexin V/PI (A) and to PARP cleavage analysis (B). *, p<0.01.
Supplementary Figure Legend from Adaptive Dosing Approaches to the Individualization of 13-Cis-Retinoic Acid (Isotretinoin) Treatment for Children with High-Risk Neuroblastoma
Authors: Veal Gareth J. , Errington Julie , Rowbotham Sophie E. , Illingworth Nicola A. , Malik Ghada , Cole Michael , Daly Ann K. , Pearson Andrew D.J. , Boddy Alan V.
Published: April 2023

PDF file - 46K