bluuebunny/crossref_metadata_2025 huggingface dataset:
QR Code as the Delivery of agent to Schools
Authors: Anita Sondhi  , Dr. Ravindra Kumar
Published: April 2022

Divider or magazine magazines are a method for conveying data on Schools grounds. In the conveyance of data, the magazine has been broadly spread in a few utilizations of Schools, iRan and GreenDoc. Be that as it may, this is as yet not ideal in light of the fact that the strategy utilized is as yet utilizing paper. And furthermore the absence of consciousness of understudies will peruse the data on the magazine. QR codes are a sort of two-layered grid code or scanner tag created by Denso Wave in 1994. With that, the type of data is decreased to a QR code that can store nitty gritty data showed on a screen accessible at a few vital corners of the grounds and output the code on the principle page of the internet based magazine site. The strategy utilized is the cascade technique, perception, and writing study and diary references as supporting recorded as a hard copy. This exploration was intended to make it more straightforward to get to data and draw in perusing interest to understudies of Schools.
Comparative Study of Conventional Extraction and Microwave Assisted Extraction of Chenopodium giganteum Leaves
Authors: Shailin Dkhar  , Akila E  , Dr. Narayanaswamy  , Pruthvi N
Published: April 2022

Microwave assisted extraction is one of the advanced techniques under thought now a days. In MAE, microwave vitality is utilized to concentrate plant metabolites with the solvents. The present study shows an efficient microwave assisted extraction (MAE) method for taking out of secondary metabolites from the medicinal plant of Chenopodium giganteum. The dried powder samples were subjected to extraction process by Conventional method as well by microwave assisted extraction and the extracts were subjected to qualitative phytochemical screening. The phytochemical screening of both the extracts revealed the presence of proteins, carbohydrates, tannins, flavonoids, terpenoids, alkaloids, phenols, glycosides.
Formulation of Healthy Cucurbita maxima seed incorporated Milkshake
Authors: H. Jerlin  , B. Keerthika  , Dr. J. Gracia
Published: April 2022

Cucurbita maxima is a popular vegetable and the seeds of Cucurbita maxima are generally considered a waste product but it is rich in bioactive compounds with nutraceutical properties. Diet rich in Cucurbita maxima seeds has been associated with a reduced risk of stomach breast, lung, prostate and colon Cancers. Seeds of Cucurbita maxima are consumed either roasted or raw and used in cooking and baking and incorporated into foods to increase the nutritional value in diets. Sensory evaluation is a combination of different senses of a perception coming into play in choosing and eating. The Objective of the study was to analyze the nutrient content of the Cucurbita maxima seed powder, to obtain a sensory evaluation of formulated products and to find out the acceptability of the product. The sample used in this study was Cucurbita maxima seed were cleaned with water to make the sample free from foreign materials, sundried and grind finely. The nutrients such as Protein, Carbohydrates, Crude fiber, Iron and Fat of the Cucurbita maxima seed powder were analyzed. Dried Cucurbita maxima powder was selected for the preparation of the milkshake. The milkshake was prepared using standard procedure. Sensory assessments were evaluated based on the quality description i.e, appearance, flavor, taste, color, texture and overall acceptability. The acceptability of the product was evaluated by a panel of 20 trained judges The data was subjected to statistical analysis such as Mean, Standard Division and Standard Error Mean. The result reveals that nutrients such as protein 6.256%, carbohydrate 23.645%, crude fiber 2.2%, Iron 0.298% and fat 49.8%. The sample Cucurbita maxima seed powder was taken to prepare the formulated product. Both the formulated products are evaluated by 20-panel members for the parameters such as appearance, taste, flavor, color, texture and overall accuracy. The appearance of formulated Cucurbita maxima seed milkshake has scored 97% in standard and 86% in the sample whereas the flavor of formulated Cucurbita maxima seed milkshake has scored 86% in standard and 96% in the sample. Taste of formulated Cucurbita maxima seed milkshake has scored 97% in standard and 98% in sample and Colour of formulated Cucurbita maxima seed milkshake has scored 92% in standard and 95% in the sample. The texture of formulated Cucurbita maxima seed milkshake has scored 92% in standard and 96% in sample respectively. Thus the present study concludes that incorporation of Cucurbita maxim seed powder in the milkshake will help to enhance the health benefit.
Synthesis of Manganese doped Bi2S3 Crystal in Gel method and its thermal Characterisations
Authors: K. B. Patil
Published: April 2022

Manganese doped Bismuth tri sulphide crystals are synthesising using simple gel technique at ambient temperature. X Ray Diffraction analysis was done to determine the structure. Orthorhombic crystal structure was found of grown crystal. FTIR method was utilized for the analysis of various functional groups present in the complex Thermal properties of the crystal was studied by TGA was Discussed .Effect of Doping, and concentration of reactants.
Membangun Koperasi Didalam Sistem Ekonomi Pasar
Authors: Ariffin Ramudi
Published: April 2022

On the one hand, it is believed that economic problems are material problems and therefore the basis of economic power is aninvestment which leads to capital (material) variables. On the other hand, they assume that the economic problem is a matter of human life and therefore the basis of economic power is the human being himself. In this case, the following explanation can be simplified to three main points, namely the market economy system, the economic system of cooperatives and cooperatives. Companies that have succeeded in a market economy system, continue to reinvest the accumulated business profits they have achieved. Then is it necessary to avoid a market economy system, Cooperative Companies are not a form of capital accumulation but the accumulation of interests or economic activities that are integrated into one group organization. The key to the strength of the Cooperative is the building of a commitment from everyone in it to always be disciplined in carrying out organizational norms and obeying in carrying out operational decisions that have been mutually agreed upon, including sanctions against those who violate it.
Análisis de necesidades y justificación para crear un modelo de planeación de la innovación del diseño de nuevos productos
Authors: Garnica González Jaime , Hernández Hernández Nancy , Niccolas Morales Heriberto
Published: April 2022

Esta investigación descriptiva tiene el propósito de mostrar el análisis de diversas técnicas, métodos y metodologías utilizadas en el diseño de nuevos productos con el objeto de plantear los argumentos que debe contener un modelo de planeación para la innovación de productos. Se realizó la localización de documentos clave, fijación de datos, análisis de contenido, clasificación y síntesis de la información, obteniendo como resultado una clasificación de las técnicas, métodos o metodologías de acuerdo a diversas áreas de análisis. Esta clasificación también indica el propósito que tienen al aplicarlas. El resultado del estudio es la discusión e implicaciones de las técnicas, métodos y metodologías identificadas en la literatura, enfatizado que en la construcción de un modelo de planeación de la innovación del diseño de productos debe hacerse explicita la relación de los diferentes planos de la planeación, como son: el normativo, estratégico, táctico, operacional y la planeación de recursos.
Nivel de desempeño en manufactura esbelta, manufactura sustentable y mejora continua
Authors: Monge Carlos
Published: April 2022

40 plantas de manufactura medianas (12) y grandes (28) de Apodaca, México, fueron encuestadas para investigar el nivel de implantación de la manufactura esbelta, la manufactura sustentable, la mejora continua y su impacto en la eficiencia operacional y responsabilidad ambiental en ellas. En las dos categorías de plantas se encontró que el desempeño es bajo. En ambos casos es preocupante que en el municipio altamente industrializado de Apodaca, México, no se estén adoptando de manera decisiva las filosofías mencionadas. Finalmente se muestran los resultados estadísticos obtenidos en las respuestas de los gerentes de planta a los ítems del cuestionario. Esta información puede ser útil a la administración de las plantas para identificar y definir acciones específicas de mejora.
Análisis financiero bajo Balanced Score Card
Authors: Gaytán Cortés Juan
Published: April 2022

La construcción de un cuadro de mando integral anima a las unidades de negocios y a las empresas a vincular sus objetivos financieros con la estrategia de la corporación.
From the Perspectives of Attitude System: A Corpus-based Study of The Time Machine
Authors: Li Jiaxin
Published: April 2022

H.G.Wells’ The Time Machine is a famous scientific fiction, but it is rich in theme. It might be regarded as a political fable or a dystopia as well as one of the first works of science fiction. Since the publication of this novel, studies on The Time Machine have mainly focused on the aspects of its genre and narrative art, and only a few studies were conducted from the linguistic perspective. Through a corpus-based method, this paper focuses on how Wells expresses his concerns about social class division and the degradation of human society in The Time Machine. Under the guidance of Appraisal Theory, Attitude resources that are related to Wells will be classified and analyzed with some appropriate examples. The findings show that Wells employs more positive Attitude resources to glorify the civilized human society represented by the Eloi and express his concern about the degradation of human civilization. This research discusses Wells attitude in The Time Machine, which provides an alternative perspective on the analysis of this novel and proves the practicability of the Attitude System in the analysis of literature works.
DoS Attack Detection and Defense on SDN Controller
Authors: Zhang Yalan , Ning Huiyun
Published: April 2022

With the development of the Internet, the flexibility and manageability problems of traditional network architecture have become increasingly prominent. To solve this problem, Software Defined Network (SDN) was born in recent years. The core idea of SDN is to decouple the data forwarding layer and the control layer, which makes SDN centralized, expandable, and programmable. The core services, important configuration, and other functions of SDN are deployed on the SDN controller, which is conducive to the centralization of network management but also introduces threats to network security. If the SDN controller is attacked, it will affect the coverage of the controller. The entire network, in extreme cases, will be paralyzed. Based on the analysis of the characteristics of the SDN network architecture, OpenFlow protocol, and the principle of DoS attacks, this project proposed and implemented two DoS detection and mitigation methods. The first one uses the Ryu controller, sFlow, and Postman to visualize and drop DoS attack traffic. The second method is a DoS attack automatic detection algorithm with a POX controller.
Transferts culturels et pédagogie : reconnecter l'histoire de nos systèmes éducatifs à leurs racines métissées
Authors: Fontaine Alexandre
Published: April 2022

For over thirty years, research on Cultural Transfer studies, nestings and mediations between cultural spaces to understand by which mechanisms idenparticularly useful methodological tools for the history of education, because it tends to decompartmentalise the educational areas of their traditional frameworks – cantonal or national – to reconnect them with their foreign references.
L'appropriation des concepts de pouvoir, de hiérarchie sociale et de territoire en histoire et éducation à la citoyenneté chez des élèves du premier cycle du secondaire au Québec
Authors: Chiasson Desjardins Sandra , Bouvier Félix , Couture Pascale
Published: April 2022

This article is about the lessons learned by students from Québec in History and Citizenship Education (HCE). More specifically, the lessons linked to the concepts found in the HCE program are the subject of this study. It enables us to document the ownership of three recurring concepts from the program: territory, social hierarchy and power. The thematic analysis helps to draw a clear picture of the ownership of concepts in the form of topic trees.
Comparison of Pain Scale, Hemodynamics, and Side Effects of Percutaneous and Intravenous Fentanyl in Post Sectio Caesaria Patients at Bunda Hospital
Authors: Moesthafa Annisa`'a Nurillah , Said Achmad Riviq , Sumarny Ros , Sumiyati Yati
Published: April 2022

This is novel research about comparison pain scale, hemodynamics, and side effects of percutaneous and intravenous fentanyl in post sectio cesarean patients. Sectio cesarean is a method of delivering a fetus through an incision in the abdominal wall (laparotomy) and the uterus wall. This method induces pain in the incision, so patients feel complicated or afraid to mobilize. Fentanyl is one of the opioid analgesics, which is the main choice in section caesarian surgery because safe for breastfeeding, is more potent than morphine, and acts as balanced anesthesia—comparing the use of percutaneous fentanyl with intravenous fentanyl with pain scale parameters, hemodynamics, and side effects in sectio caesarian patients at Bunda Mother and Child Hospital Jakarta. Before conducting this research, an observational study first makes an ethical approval. Data were taken prospectively and collected simultaneously to compare percutaneous and intravenous fentanyl performed on post sectio cesarean patients with the physical status of the American Society of Anesthesiologists (ASA) I–II at Bunda Mother and Child Hospital Jakarta from September to November 2020. Comparative data observed were pain scale parameters, hemodynamics, and side effects after percutaneous fentanyl therapy or intravenous fentanyl therapy. Data were processed using SPSS 22 version and Microsoft Excell 2016. In conclusion, intravenous fentanyl is more effective in reducing pain scale and has more minor side effects than percutaneous fentanyl. There is no significant difference in hemodynamic parameters (p-value >0.05).
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 5 No. 1 February 2022
Authors: Borneo J Pharm Chief Editor Of
Published: April 2022

Assalamu’alaikum Wr. Wb.

Alhamdulillahirabbil ‘alamin. The next edition of the Borneo Journal of Pharmacy (Borneo J Pharm), has been published in February 2022. This edition contains ten articles consisting of Pharmacognosy-Phytochemistry, Clinical-Community Pharmacy, Pharmaceutical, Microbiology Pharmacy, and Natural Product Development. This edition includes writings from three countries including Azerbaijan, Indonesia, and Ukraine. The authors come from several institutions, including Universitas Lambung Mangkurat, Universitas Pancasila, Bunda Mother and Child Hospital Jakarta, National University of Pharmacy, Kharkiv National University of Radio Electronics, Universitas Jenderal Achmad Yani, Institut Teknologi Bandung, Universitas Tanjungpura, Universitas Muhammadiyah Kalimantan Timur, Sekolah Tinggi Ilmu Farmasi Makassar, Universitas Gadjah Mada, Universitas Airlangga, and Azerbaijan Medical University.

Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors, could re-participate for publication in the next edition in May 2022.

Wassalamu’alaikum Wr. Wb.
Upaya Pencegahan COVID-19 melalui Peningkatan Pengetahuan Ibu mengenai PHBS di Lingkungan Keluarga pada Masa Pandemi
Authors: Nursolihati Vidya , Ariyani Annisaa Putri , Zubardiah Lies , Pakpahan Alfred , Assyidiqie Iqbal Zein
Published: April 2022

Until now, there is still no specific treatment that has proven effective for COVID-19, so prevention of the disease is the best way to break the chain of its transmission. This prevention effort requires participation from the entire community. However, it is not easy for people to participate due to a lack of understanding about the disease and awareness of clean-living behavior to prevent infection. Yayasan Rumah Ibu Indonesia (Rumaisa) is a foundation that focuses on increasing family resilience. One of the targets for clean and healthy living behavior (PHBS) is household/family; therefore, PHBS education and training in homes during the pandemic, especially for mothers, is a strategic way to mobilize and empower family members to practice clean and healthy behavior. This study aims to determine the effect of education and training of PHBS within families during the pandemic on mothers’’ knowledge in Yayasan Rumaisa. Participants’ level of knowledge is measured using a questionnaire given before and after the education and training, in the form of pre-test and post-test. From the results, it can be seen that the post-test scores were increased compared to the pre-test scores. An increase in participants’ knowledge of PHBS within families during the pandemic is expected to increase community participation in preventing disease transmission, especially COVID-19.
Upaya Optimalisasi Lahan Bawah Tegakan pada Zona Tradisional melalui Sosialisasi Budidaya Nilam kepada Pengaram di Taman Hutan Raya K.G.P.A.A. Mangkunagoro I
Authors: Pertiwi Yus Andhini Bhekti , Nufus Malihatun , Wicaksono Rezky Lasekti , Rahmadwiati Rissa , Agustina Ana , Nayasilana Ike Nurjuita
Published: April 2022

The socialization of patchouli cultivation was conducted at Forest Park (Tahura) K.G.P.A.A. Mangkunagoro I, located at Mount Lawu, in Berjo Village, Ngargoyoso District Karanganyar Regency. Tahura K.G.P.A.A. Mangkunagoro I was divided into several zones. The most critical zone for the local community is the traditional zone. So far, the traditional zone was used by the community/forest farmers (pengaram) to plant grass (Pennisetum purpureum) under the main stand. The grass was planted mainly for animal feed or sale. During the dry season, the main problem was that the grass did not grow well. Thus, forest farmers do not have additional income from the traditional zone. For this reason, it was necessary to enrich understorey species that mainly have high economic and ecological values. One of the potential plants to be developed understands at traditional zone was patchouli (Pogostemon cablin Benth.). Patchouli is an essential oil-producing plant. It is easy to cultivate and has high economic value. The purpose of this community service was to provide knowledge to forest farmers about patchouli plants. The activities carried out in this program were providing counseling to forest farmers about the theory related to patchouli cultivation and its benefits, business opportunities, oil processing, and mentioned costs and income from patchouli cultivation. The result shows that the knowledge about patchouli cultivation was new for the forest farmers. Forest farmers and Tahura K.G.P.A.A. Mangkunagoro I staff showed interest in cultivating patchouli under forest stands in traditional zones.
Tangguh Hadapi Covid-19 dengan Budidaya Tanaman Obat Keluarga di Desa Margomulyo, Seyegan, Sleman
Authors: Probowati Wiwit , Torizal Fuad Gandhi , Sunartiyah Sunartiyah
Published: April 2022

During the Covid-19 outbreak, it is essential to maintain faith and a happy soul; it is also necessary to maintain our health immunity. The body's immunity can be supported by consuming healthy food and a balanced diet. Consumption of additional supplements from chemical medicine cause side effects if consumed overdoses. By utilizing the land yard for the cultivation of herbal plants, it can be used as an alternative solution to reduce the consumption of chemical drugs, in line with the problems faced by the program partner nursery, which has an extensive collection of medicinal plants but does not yet know the efficacy of each type of plant. The community service program during the pandemic was carried out through limited counseling to 30 health cadres of Margomulyo village. The method used in this activity is public education through lectures, questions, and discussions. Participants were also given a pocketbook "List of Herbal Plants and their benefits and also given plant seeds. Participants' level of knowledge was measured using a questionnaire given before and after the lecture. From the results, it can be seen that there is an increase in the understanding of the participant's post-test scores compared to pre-test scores. Participants' increased knowledge about family medicinal plants was expected to share the knowledge with the broader community and apply the cultivation of herbal plants inland around the house.
Cover, Content, and Editorial Note from Pengabdianmu J Pengabdian Masyarakat Vol. 7 No. Special-1 February 2022
Authors: PengabdianMu J Pengabdian Masyarakat Chief Editor Of
Published: April 2022

Assalamu’alaikum Wr. Wb.

Dear reader, now PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat re-published on Volume 7 Special Issue 1 February 2022. This edition marks a change in publication frequency from four times to six times a year.

The publication of PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat certainly participates in disseminating the results of community services in science and technology development conducted by lecturers and researchers, especially from UMPR and other universities.

This edition contains 20 articles consisting of Education, Social and Political, Agriculture, and Health Science topics. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions.

The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate the success of the publication in the next edition in March 2022.

Wassalamu’alaikum Wr. Wb.
Differentiating individuals of Armillaria species in New Zealand forests
Authors: Dodd Sarah , Shah Farhat , Kimberley Mark , Somchit Chanatda , Hood Ian
Published: April 2022

Background: Armillaria novae-zelandiae and A. limonea occur naturally as wood decay fungi in native forests in New Zealand. As pathogens they are responsible for significant root disease in trees and shrubs in plantations, crops and urban parks and gardens. A thorough understanding of their population dynamics entails knowledge of the spatial arrangement of their individual mycelia or genets. In previous work the distributions of vegetative compatibility groups (VCGs) of these fungi were mapped in an area of native forest prior to and after replacement by a young Pinus radiata plantation. With the advent of molecular technology, it has become possible to test species identities made earlier using culture techniques and to verify whether or not their VCGs, determined by incompatibility reactions between paired cultures, represent distinct individual genets. Methods: Stock subcultures of isolates representing each VCG were recovered from storage in order to obtain DNA. Extracted DNA was subjected to a polymerase chain reaction procedure (UP-PCR) using 11 universal primers to assess genetic variation between subcultures. Bands were scored as either present or absent for each primer-subculture combination and cluster analysis was undertaken by generating dendrogram trees to reveal genetic groupings among subcultures.   Results: DNA cluster analysis divided subcultures of isolates into two species groups, A. novae-zelandiae and A. limonea, corresponding to identities determined through culture morphology. Within species, subcultures grouped into clusters that matched VCGs determined by earlier culture pairing. There was little indication of genetic variation within VCGs, except for one of A. limonea, which comprised two sub-clusters. Conclusions: The Armillaria species and VCGs identified by culture techniques in the laboratory were verified by independent molecular methodology. In general, the VCGs represent discrete individual genets or colonies in the field. Techniques that differentiate isolates based on differences in their DNA sequence provide a quick alternative to time-consuming laboratory culture methods for resolving population spatial structure. However, some complementary isolate pairing may be necessary when rationalising the significance of groupings in dendrogram trees.
KEUDUDUKAN PPAT DALAM PELAKSANAAN HAK TANGGUNGAN SECARA ELEKTRONIK DALAM HUKUM POSITIF INDONESIA
Authors: Harniwati Harniwati
Published: April 2022

PPAT in carrying out his position must be careful. As an official whose signature is capable of causing a transfer of rights, it is only natural that the PPAT act prudently in carrying out the duties of his position. Because every form of authority is given by law, there is also legal responsibility. There will be no authority that is not accompanied by legal responsibility. In addition to the installation of electronic Mortgages raises legal responsibility, the process of installing electronic Mortgages also raises obstacles. A very influential constraint is the internet network. This is because the process of installing Mortgage Rights is already electronic, so of course this will depend on the internet network itself. The process of validation, checking certificates, and registration of Mortgage are very dependent on good internet quality. The validation process is carried out by the Land Office, if the internet network is bad, it will take more time in the validation process. During the process of moving until the internet network is installed at the new Land Office, certificate validation services cannot be performed. Then this also has an impact on certificate checking services by PPAT and electronic Mortgage registration, because the network on the Partner Application is directly connected to the internet network at the Land Office. So that PPAT in the installation of electronic Mortgage, is not only faced with its responsibilities in carrying out the position but also must be ready to face the existing obstacles, especially obstacles in the installation of electronic Mortgage.Keywords: PPAT, Mortgage, Electronic.
MENGENAL SISTEM PEMERINTAHAN NAGARI DI PROPINSI SUMATERA BARAT
Authors: Zakir Fauzan
Published: April 2022

Nagari is a customary law community unit in the province of West Sumatra which consists of a collection of several tribes that have certain territorial boundaries, have their own assets, have the right to regulate and manage their own household in choosing their government leaders. Nagari is also a family unit that is larger than the tribe, the nagari usually consists of approximately 4 (four) tribes, namely a large family that is related by blood from several lungs according to the mother's lineage. Historically, the nagari government is a traditional government ruled by tribal leaders who have the same authority who are incorporated in a customary density. These penghulu are assisted by the manti (smart people trusted by the penghulu), malin (clerics), and dubalang (hulubalang/security). The Nagari Government as the lowest government that replaces the Village Government is a unitary community of customary law in the area of West Sumatra Province. Consists of a collection of several tribes that have an area with certain boundaries, have their own wealth, have the right to regulate and manage their household and choose their government leaders.Keywords: Government System, Nagari, West Sumatra.
PREVALENSI KASUS REAKTIF HBsAg PADA PENDONOR DENGAN METODE ChLIA DAN ELISA BERDASARKAN USIA DAN JENIS KELAMIN DI UDD PMI KOTA DEPOK PADA TAHUN 2019-2020
Authors: Indah Hippy Nova Surya , Ukma Nurliani
Published: April 2022

Latar belakang: Hepatitis B merupakan salah satu penyakit yang paling infeksius dibandingkan dengan jenis penyakit Hepatitis yang lain. Indonesia merupakan salah satu negara berkembang yang memiliki prevalensi Hepatitis B tertinggi kedua setelah negara Myanmar. Tingginya jumlah prevalensi infeksi virus Hepatitis B tersebut di Indonesia disebabkan karena rendahnya kesadaran masyarakat terhadap penyakit Hepatitis B dan bahkan sebagian besar mungkin tidak memahami apa yang dimaksud dengan Hepatitis B. Tujuan penelitian: untuk mengetahui jumlah prevalensi kasus reaktif HBsAg pada pendonor dengan metode ChLIA dan ELISA berdasarkan usia dan jenis kelamin di UDD PMI kota Depok pada tahun 2019-2020. Jenis penelitian: penelitian deskriptif. Hasil penelitian: pada tahun 2019 didapatkan hasil reaktif HBsAg sebanyak 242 (0,88%) dari 27.519 pendonor dengan prevalensi terbanyak pada kelompok ≤ 18 tahun yaitu 1,16% dan jenis kelamin laki-laki yaitu 0,92% serta metode pemeriksaan terdapat pada metode ELISA yaitu 0,93%. Sedangkan pada tahun 2020 didapatkan hasil reaktif HBsAg sebanyak 171 (0,82%) dari 20.926 pendonor dengan prevalensi terbanyak pada kelompok 45 – 59 tahun yaitu 1.26% dan jenis kelamin laki-laki yaitu 0,89% serta metode pemeriksaan terdapat pada metode ELISA yaitu 0,97%. Kesimpulan: pada tahun 2019-2020, prevalensi tertinggi ada pada pendonor dengan kelompok usia ≤18 tahun dan usia 45 – 59 tahun pada pendonor darah laki-laki dengan menggunakan metode ELISA.Keywords: ChLIA, ELISA, HBsAg, Jenis kelamin, Usia
MANIFESTASI PRINSIP MORAL DALAM PEMBENTUKAN PENGADILAN PIDANA INTERNASIONAL
Authors: Situngkir Danel Aditia
Published: April 2022

The establishment of the International Criminal Court is an answer to the view of natural law regarding past events where to try the perpetrators of serious crimes against human rights an ad hoc international criminal court was formed which violates the provisions that have been considered rigid as law by positivists. In view of natural law, the provisions referred to in the Rome Statute are formed which are the basis for the establishment of an international criminal tribunal that has the authority to try perpetrators of crimes of genocide, crimes against humanity, war crimes and crimes of aggression. According to adherents of natural law theory, natural law doctrines will always color and inspire positive law, so that positive law always goes on the right track, both when laws are made, implemented and when used by judges in deciding cases in court. Natural law offers options through its higher-trusted rules. In this case the law of nature will function as an opposition to a tyrannical government (repeated often in history). The laws of nature are also dual in nature. At one end its function is to protect the rights, freedoms and independence of individuals, at the other end in a country, natural law as the embodiment of the highest value functions as a cry for a nation's integrity, in which operational forms of social solidarity, the common good, the public interest or social consensus.
PEMBERDAYAAN UMKM PADA MASA PANDEMI COVID-19 DI KOTA PEKANBARU
Authors: Fahrial Fahrial , Shandy Utama Andrew
Published: April 2022

One of the goals of the establishment of Indonesia as a country is to improve the welfare of the people. The Covid-19 pandemic that has hit Indonesia since March 2020 has greatly affected the condition of the national economy, including in Pekanbaru City. The method used in this research is sociological law research. The strategy that can be applied by MSME actors in Pekanbaru City to survive during the Covid-19 pandemic is to make creative innovations that do not violate government policies. Law Number 20 of 2008 concerning Micro, Small and Medium Enterprises stipulates that the government is obliged to empower MSMEs in order to maintain national economic stability. Law Number 20 of 2008 concerning Micro, Small and Medium Enterprises stipulates that the forms of empowering MSMEs that must be carried out by the government include funding assistance, improving facilities and infrastructure, information on business opportunities, partnership programs, facilitating business licensing, providing business opportunities, conducting trade promotion activities, as well as institutional support.Keywords: MSMEs, Empowerment, Covid-19 Pandemic
Supervivencia de pacientes con cáncer de cérvix estadio clínico III y IV, sometidas a nefrostomía: Estudio descriptivo de centro único
Authors: Muñoz Viteri María José , Muñoz Bermeo René Arturo , Caballero Narváez Henry Marcelo
Published: April 2022

Introducción: La cuarta parte de las mujeres con neoplasias ginecológicas cursa con obstrucción en la vía urinaria, secundaria a infiltración tumoral o compresión extrínseca de los uréteres. La nefrostomía es la alternativa clínica intervencionista para mejorar la nefropatía obstructiva y evitar el tratamiento de diálisis en un paciente oncológico con hidronefrosis. El presente estudio tiene el objetivo de determinar la supervivencia de pacientes con cáncer de cérvix portadoras de nefrostomía.

Metodología: El presente estudio observacional se realizó en el Hospital Solón Espinosa Ayala “Solca-Núcleo de Quito” de enero-2014 a diciembre-2018. El cálculo muestral fue no probabilístico, se incluyeron casos de pacientes con cáncer de cérvix con nefrostomía. Las variables fueron: edad, supervivencia global, supervivencia con nefrostomía, tipo histológico de la neoplasia de cérvix, estadío, tratamiento oncológico luego de la nefrostomía, complicaciones y repuesta al tratamiento. Para el análisis se usó el método Kaplan Meier. Se analiza supervivencia según estadios funcionales ECOG.

Resultados: Se incluyeron 96 casos en el estudio. La media de sobrevida luego de colocar la nefrostomía fue de 277 días (9.2 meses), y la media de la sobrevida global fue de 462 días (15 meses). Las pacientes con ECOG-0 la supervivencia global fue de 625 días (20.8 meses), con ECOG 1, 2 y 3 fue de 437 días (14.5 meses) P= 0.013.

Conclusión: Es este estudio las pacientes con cáncer de cérvix que tienen enfermedad localmente avanzada y metastásica con ECOG 0, son las más beneficiadas del procedimiento de nefrostomía con mejoría de la supervivencia. Las pacientes con enfermedad localmente avanzada y metastásica con ECOG 2 y 3, no mejoraron su sobrevida global con la colocación de nefrostomía, ya que a pesar de que recibieron tratamiento oncológico el 50% de ellas progresaron, pero evitaron el ingreso a programas de diálisis. La principal complicación luego de la colocación del catéter de nefrostomía fue la infección.
Trastornos psiquiátricos posteriores al diagnóstico oncológico de primera vez
Authors: Vivanco Muñoz Karla Elizabeth , Ibañez Limaico José Luis , Estévez Montalvo Luis Edmundo
Published: April 2022

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A Brave New World: Virtual Reality and Augmented Reality in Systems Biology
Authors: Turhan Berk , Gümüş Zeynep H.
Published: April 2022

How we interact with computer graphics has not changed significantly from viewing 2D text and images on a flatscreen since their invention. Yet, recent advances in computing technology, internetworked devices and gaming are driving the design and development of new ideas in other modes of human-computer interfaces (HCIs). Virtual Reality (VR) technology uses computers and HCIs to create the feeling of immersion in a three-dimensional (3D) environment that contains interactive objects with a sense of spatial presence, where objects have a spatial location relative to, and independent of the users. While this virtual environment does not necessarily match the real world, by creating the illusion of reality, it helps users leverage the full range of human sensory capabilities. Similarly, Augmented Reality (AR), superimposes virtual images to the real world. Because humans learn the physical world through a gradual sensory familiarization, these immersive visualizations enable gaining familiarity with biological systems not realizable in the physical world (e.g., allosteric regulatory networks within a protein or biomolecular pathways inside a cell). As VR/AR interfaces are anticipated to be explosive in consumer markets, systems biologists will be more immersed into their world. Here we introduce a brief history of VR/AR, their current roles in systems biology, and advantages and disadvantages in augmenting user abilities. We next argue that in systems biology, VR/AR technologies will be most useful in visually exploring and communicating data; performing virtual experiments; and education/teaching. Finally, we discuss our perspective on future directions for VR/AR in systems biology.
Transdifferentiation of Myoblasts Into Adipocytes by All-Trans-Retinoic Acid in Avian
Authors: Kim Dong-Hwan , Lee Joonbum , Suh Yeunsu , Ko Jae-Kyun , Lee Kichoon
Published: April 2022

Increased adipogenesis in muscle tissues is related to metabolic syndromes and muscle weakness in humans and improvement of meat quality in animal production. With growing evidence for pro-adipogenic functions of all-trans-retinoic acid (atRA), the current study investigated whether atRA can transdifferentiate myoblasts into adipocytes using a quail myogenic cell line (QM7) and avian primary myoblasts. atRA increased cytoplasmic lipid droplet accumulation and mRNA expression for adipogenic genes in these cells. An acute induction of Pparγ expression by atRA under cycloheximide treatment indicated a direct regulation of Pparγ by atRA. In addition, the induction of Pparγ expression was mediated by retinoic acid receptors . At high levels of Pparγ by atRA, BADGE, an antagonist of Pparγ, inhibited, and rosiglitazone, an agonist of Pparγ, further enhanced atRA-induced transdifferentiation. However, at very low levels of Pparγ in the absence of atRA treatment, rosiglitazone could not induce transdifferentiation of avian myoblasts. These data suggest that the induction of Pparγ expression by atRA is an essential molecular event in myoblasts for atRA-induced transdifferentiation into adipocytes. Based on our findings, atRA can be a new transdifferentiation factor of myoblasts to adipocytes, providing a potential nutrient to enhance marbling in poultry.
Stress Prediction of the Particle Structure of All-Solid-State Batteries by Numerical Simulation and Machine Learning
Authors: Komori Chiyuri , Ishikawa Shota , Nunoshita Keita , So Magnus , Kimura Naoki , Inoue Gen , Tsuge Yoshifumi
Published: April 2022

All-Solid-state batteries (ASSBs) are non-flammable and safe and have high capacities. Thus, ASSBs are expected to be commercialized soon for use in electric vehicles. However, because the electrode active material (AM) and solid electrolyte (SE) of ASSBs are both solid particles, the contact between the particles strongly affects the battery characteristics, yet the correlation between the electrode structure and the stress at the contact surface between the solids remains unknown. Therefore, we used the results of numerical simulations as a dataset to build a machine learning model to predict the battery performance of ASSBs. Specifically, the discrete element method (DEM) was used for the numerical simulations. In these simulations, AM and SE particles were used to fill a model of the electrode, and force was applied from one direction. Thus, the stress between the particles was calculated with respect to time. Using the simulations, we obtained a sufficient data set to build a machine learning model to predict the distribution of interparticle stress, which is difficult to measure experimentally. Promisingly, the stress distribution predicted by the constructed machine learning model showed good agreement with the stress distribution calculated by DEM.
Ultrasensitive Detection of Ochratoxin A With a Zeolite Imidazolate Frameworks Composite–Based Electrochemical Aptasensor
Authors: Ni Xiao , Zhang Yuyan , Xue Chuhan , Chen Xiaojun
Published: April 2022

Ochratoxin A (OTA) is a harmful mycotoxin, which is mainly secreted by Penicillium and Aspergillus species. In this work, an electrochemical aptasensor is presented for OTA detection based on Au nanoparticles (AuNPs) modified zeolite imidazolate frameworks (ZIFs) ZIF-8 platform and duplex-specific nuclease (DSN) triggered hybridization chain reaction (HCR) signal amplification. G-quadruplex-hemin assembled HCR nanowire acted as a nicotinamide adenine dinucleotide (NADH) oxidase and an HRP-mimicking DNAzyme. Besides, thionine (Thi) was enriched as a redox probe for signal amplification in this pseudobienzyme electrocatalytic system. Under the optimal conditions, the analytical response ranged from 1 to 107 fg ml−1 with a detection limit of 0.247 fg ml−1. Furthermore, the aptasensor was proven to be applied in real wheat samples with a recovery between 96.8 and 104.2%, illustrating the potential prospects in practical detection.
Ultrasonic-Assisted Synthesis of CdS/Microcrystalline Cellulose Nanocomposites With Enhanced Visible-Light-Driven Photocatalytic Degradation of MB and the Corresponding Mechanism Study
Authors: Zhu Chaosheng , Zhang Xiangli , Zhang Yongcai , Li Yunlin , Wang Ping , Jia Yanchi , Liu Jin
Published: April 2022

A simple and efficient ultrasonic-assisted approach was designed to synthesize CdS/microcrystalline cellulose (MCC) nanocomposite photocatalyst. The obtained products have been characterized by XRD, FE-SEM, TEM, UV-Vis DRS, and nitrogen adsorption isotherms. The results showed that the intimate contact of MCC and CdS is beneficial for enhancing the photocatalytic performance because heterojunction formation can efficiently promote the separation of photogenerated electrons and holes of the nanocomposite photocatalyst. By using 10% MCC coupled CdS, the decoloration rate of methylene blue (MB) in the solution under visible-light was increased nearly 50%. In addition, the reuse experiments confirmed that the CdS/MCC nanocomposite photocatalyst had outstanding cycle performance and durability. Mechanism study demonstrated that hydroxyl radicals, photogenerated holes and superoxide radicals were the active species in the photocatalytic oxidization degradation of MB.
Time Is Ripe to Make Interactional Moves: Bringing Evidence From Four Languages Across Modalities
Authors: Lepeut Alysson , Shaw Emily
Published: April 2022

Sign language linguistics has largely focused on lexical, phonological, and morpho-syntactic structures of sign languages, leaving the facets of interaction overlooked. One reason underlying the study of smaller units in the initial stages of development of the field was a pressing concern to ground sign languages as linguistic. The interactive domain has been sidestepped in gesture studies, too, where one dominant approach has been rooted in psycholinguistic models arguing for gesture’s tight relationship with speech as part of language. While these approaches to analyzing sign and gesture have been fruitful, they can lead to a view of language as abstracted from its natural habitat: face-to-face interaction. Such an understanding of how language manifests itself—one that takes for granted the conversational exchange—cannot account for the interactional practices deployed by deaf and hearing individuals within and across various ecological niches. This paper reviews linguistic research on spoken and sign languages, their approaches to gesture that have tended to posit a divide between what is linguistic vs. non-linguistic and sign vs. gesture. Rather than opposing the two, this paper argues for seeing the dynamics between gesture and sign as intimately intertwined both intra- and inter-personally. To ground this claim, we bring evidence from four languages: ASL—American English and French Belgian Sign Language (LSFB)-Belgian French across modalities (signed and spoken) to offer a view of language as situated, dynamic and multimodal. Based on qualitative corpus analyses of signers’ and speakers’ face-to-face interactional discourses of two communicative actions, viz. palm-up and index pointing, it is exemplified how deaf ASL-LSFB and American English-Belgian French hearing individuals mobilize their hands to continuously contribute to both linguistic meaning and the management of their social actions with addressees. Ultimately, exploring the interactional synergies arising within and across different communicative ecologies enables scholars interested in the fields of gesture and sign language research to gain a better understanding of the social, heterogeneous nature of language, and as to what it means for spoken and sign languages to be embodied languages.
Automatic Detection of Secundum Atrial Septal Defect in Children Based on Color Doppler Echocardiographic Images Using Convolutional Neural Networks
Authors: Hong Wenjing , Sheng Qiuyang , Dong Bin , Wu Lanping , Chen Lijun , Zhao Leisheng , Liu Yiqing , Zhu Junxue , Liu Yiman , Xie Yixin , Yu Yizhou , Wang Hansong , Yuan Jiajun , Ge Tong , Zhao Liebin , Liu Xiaoqing , Zhang Yuqi
Published: April 2022

Secundum atrial septal defect (ASD) is one of the most common congenital heart diseases (CHDs). This study aims to evaluate the feasibility and accuracy of automatic detection of ASD in children based on color Doppler echocardiographic images using convolutional neural networks. In this study, we propose a fully automatic detection system for ASD, which includes three stages. The first stage is used to identify four target echocardiographic views (that is, the subcostal view focusing on the atrium septum, the apical four-chamber view, the low parasternal four-chamber view, and the parasternal short-axis view). These four echocardiographic views are most useful for the diagnosis of ASD clinically. The second stage aims to segment the target cardiac structure and detect candidates for ASD. The third stage is to infer the final detection by utilizing the segmentation and detection results of the second stage. The proposed ASD detection system was developed and validated using a training set of 4,031 cases containing 370,057 echocardiographic images and an independent test set of 229 cases containing 203,619 images, of which 105 cases with ASD and 124 cases with intact atrial septum. Experimental results showed that the proposed ASD detection system achieved accuracy, recall, precision, specificity, and F1 score of 0.8833, 0.8545, 0.8577, 0.9136, and 0.8546, respectively on the image-level averages of the four most clinically useful echocardiographic views. The proposed system can automatically and accurately identify ASD, laying a good foundation for the subsequent artificial intelligence diagnosis of CHDs.