bluuebunny/crossref_metadata_2025 huggingface dataset:
Designing Our Own Board Games in the Playful Space: Improving High School Student’s Citizenship Competencies and Creativity through Game-Based Learning
Authors: Kuo Hsu-Chan , Weng Tzu-Lien , Chang Chih-Ching , Chang Chu-Yang
Published: February 2023

The nurturing of a student’s core competencies and creativity has been promoted and prioritized as one of the main axes in education worldwide, which has also been emphasized in Taiwan’s new curriculum guidelines. This study aims to develop a new creative teaching and learning approach—“Self-designed Board Games” (SdBG), in which the students work in groups to design and play their self-designed board games in high school citizenship studies. The study further investigates the impact of SdBG on the students’ citizenship competencies and creativity. A quasi-experimental design was employed throughout one semester; 76 high school students were randomly assigned to either the experimental group (SdBG) or the comparison group (traditional lecturing teaching). The experimental group was asked to develop board games based on their interests and the learning contents of the 18- week semester. Later, all of the experimental group students played the board games developed by themselves and other fellow students. The main findings are as follows: (a) Citizenship competencies: the experimental group experienced a significant improvement in citizenship competencies, whereas no significant difference was found in the control group. (b) Creativity: the experimental group witnessed great improvements in all four facets of creativity, including fluency, flexibility, originality, and elaboration, whereas the control group experienced significant regression in all four facets in the pretest and post-test. To our knowledge, this is the first study that creates a so-called “Playful Space”, enabling students to play their self-designed board games and simultaneously investigates its impact on citizenship competencies and creativity. Evidence revealed that the SdBG is an effective approach in Citizenship studies, which offers the warrant for the study to make theoretical and practical contributions to the field and knowledge.
Investigating the Relationship between Landscape Design Types and Human Thermal Comfort: Case Study of Beijing Olympic Forest Park
Authors: Zhang Lin , Xu Haiyun , Pan Jianbin
Published: February 2023

Urban green space can improve the local thermal environment and thus the quality of the urban residential environment. Taking the green space of Beijing Olympic Forest Park (BOFP) as an example, this study analysed sample points representing different plant community structures, plant community types, and landscape environments based on 15 years of continuous dynamic measurement and selected typical annual data (from 2020). The study analysed and explained the spatial differentiation characteristics of human thermal comfort (HTC) in green space areas of BOFP using the predicted mean vote (PMV)–predicted percentage dissatisfied (PPD) physical comfort index model, which comprehensively considers both the objective environment and people’s subjective feelings and psychological states. The results showed that the level of HTC in the park’s green space, across community types and across typical landscape environments, differed between areas with different community structures. PMV–PPD mathematical model fitting further verified the above results.
Applicability Evaluation of Energy Slabs Installed in an Underground Parking Lot
Authors: Lee Seokjae , Park Sangwoo , Han Taek Hee , Won Jongmuk , Choi Hangseok
Published: February 2023

A floor slab of buildings can be used as a ground heat exchanger by equipping heat exchange pipes with a horizontal layout, namely energy slabs. The thermal performance of conventional energy slabs is relatively low due to the interference with the ambient air temperature. This fatal drawback can be overcome by installing energy slabs in an underground parking lot, where the influence of ambient air is not significant. This study experimentally investigated the applicability of two types of energy slabs (floor type and wall type), which were constructed on the basement slab in an underground parking lot. In particular, an aerogel-type thermal insulation layer was fabricated in each energy slab to isolate it from the ambient air along with enhancing the structural stability against automobiles. In the thermal performance tests, the constructed energy slabs showed a thermal performance 265% higher than the conventional energy slabs. Moreover, the aerogel-type thermal insulation layer effectively prevented surface condensation. However, the thermal stress of 2350 kPa was induced by the cooling operation in the energy slabs, which means the energy slab should possess sufficient tensile strength to secure the structural integrity of the parking lot basement.
Higher Order Non-Planar Electrostatic Solitary Potential in a Streaming Electron-Ion Magnetoplasma: Phase Plane Analysis
Authors: Khan Khalid , De la Sen Manuel , Irfan Muhammad , Ali Amir
Published: February 2023

We investigate cylindrical and spherical solitons in electron-ion (EI) plasma that contains hot (cold) electrons with stationary ions. The magneto-hydrodynamic equations are solved with the aid of the reductive perturbation (RP) technique, leading to the modified Korteweg–De Vries (mKdV) equation for the non-linear behaviour of the solitary waves in EI plasma. By employing the reduced differential transform method (RDTM), an approximate solution of the mKdV is obtained for solitary waves. Phase plane analysis reveals that these excitations exhibit periodic oscillations. The phase plane and periodic behaviour of the obtained model are studied. It is observed that the amplitude and width of the electron acoustic waves (EAWs) are affected by a slight change in the cold to hot electron temperature ratio (σc) and the number density of the cold to hot electron ratio (α). The effect of the streaming speed u(0) and superthermality index κe are investigated. This study is important for understanding the symmetric properties of cylindrical and spherical plasma, relying on the bifurcation analysis, impacted by the streaming effect in the EI plasma.
Genuine q-Stancu-Bernstein–Durrmeyer Operators
Authors: Sabancıgil Pembe
Published: February 2023

In the present paper, we introduce the genuine q-Stancu-Bernstein–Durrmeyer operators Znq,α(f;x). We calculate the moments of these operators, Znq,α(tj;x) for j=0,1,2, which follows a symmetric pattern. We also calculate the second order central moment Znq,α((t−x)2;x). We give a Korovkin-type theorem; we estimate the rate of convergence for continuous functions. Furthermore, we prove a local approximation theorem in terms of second modulus of continuity; we obtain a local direct estimate for the genuine q-Stancu-Bernstein–Durrmeyer operators in terms of Lipschitz-type maximal function of order β and we prove a direct global approximation theorem by using the Ditzian-Totik modulus of second order.
Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom
Authors: Malyarenko Dariya , Amouzandeh Ghoncheh , Pickup Stephen , Zhou Rong , Manning Henry Charles , Gammon Seth T. , Shoghi Kooresh I. , Quirk James D. , Sriram Renuka , Larson Peder , Lewis Michael T. , Pautler Robia G. , Kinahan Paul E. , Muzi Mark , Chenevert Thomas L.
Published: February 2023

Relevant to co-clinical trials, the goal of this work was to assess repeatability, reproducibility, and bias of the apparent diffusion coefficient (ADC) for preclinical MRIs using standardized procedures for comparison to performance of clinical MRIs. A temperature-controlled phantom provided an absolute reference standard to measure spatial uniformity of these performance metrics. Seven institutions participated in the study, wherein diffusion-weighted imaging (DWI) data were acquired over multiple days on 10 preclinical scanners, from 3 vendors, at 6 field strengths. Centralized versus site-based analysis was compared to illustrate incremental variance due to processing workflow. At magnet isocenter, short-term (intra-exam) and long-term (multiday) repeatability were excellent at within-system coefficient of variance, wCV [±CI] = 0.73% [0.54%, 1.12%] and 1.26% [0.94%, 1.89%], respectively. The cross-system reproducibility coefficient, RDC [±CI] = 0.188 [0.129, 0.343] µm2/ms, corresponded to 17% [12%, 31%] relative to the reference standard. Absolute bias at isocenter was low (within 4%) for 8 of 10 systems, whereas two high-bias (>10%) scanners were primary contributors to the relatively high RDC. Significant additional variance (>2%) due to site-specific analysis was observed for 2 of 10 systems. Base-level technical bias, repeatability, reproducibility, and spatial uniformity patterns were consistent with human MRIs (scaled for bore size). Well-calibrated preclinical MRI systems are capable of highly repeatable and reproducible ADC measurements.
Interlaboratory Study to Evaluate a Testing Protocol for the Safety of Food Packaging Coatings
Authors: Marin-Kuan Maricel , Pagnotti Vincent , Patin Amaury , Moulin Julie , Latado Helia , Varela Jesús , Hammel Yves-Alexis , Gude Thomas , Moor Heidi , Billinton Nick , Tate Matthew , Behnisch Peter Alexander , Besselink Harrie , Burleigh-Flayer Heather , Koster Sander , Szabo David T.
Published: February 2023

According to European regulations, migration from food packaging must be safe. However, currently, there is no consensus on how to evaluate its safety, especially for non-intentionally added substances (NIAS). The intensive and laborious approach, involving identification and then quantification of all migrating substances followed by a toxicological evaluation, is not practical or feasible. In alignment with the International Life Sciences Institute (ILSI) and the European Union (EU) guidelines on packaging materials, efforts are focused on combining data from analytics, bioassays and in silico toxicology approaches for the risk assessment of packaging materials. Advancement of non-targeted screening approaches using both analytical methods and in vitro bioassays is key. A protocol was developed for the chemical and biological screening of migrants from coated metal packaging materials. This protocol includes guidance on sample preparation, migrant simulation, chemical analysis using liquid chromatography (LC-MS) and validated bioassays covering endocrine activity, genotoxicity and metabolism-related targets. An inter-laboratory study was set-up to evaluate the consistency in biological activity and analytical results generated between three independent laboratories applying the developed protocol and guidance. Coated packaging metal panels were used in this case study. In general, the inter-laboratory chemical analysis and bioassay results displayed acceptable consistency between laboratories, but technical differences led to different data interpretations (e.g., cytotoxicity, cell passages, chemical analysis). The study observations with the greatest impact on the quality of the data and ultimately resulting in discrepancies in the results are given and suggestions for improvement of the protocol are made (e.g., sample preparation, chemical analysis approaches). Finally, there was agreement on the need for an aligned protocol to be utilized by qualified laboratories for chemical and biological analyses, following best practices and guidance for packaging safety assessment of intentionally added substances (IAS) and NIAS to avoid inconsistency in data and the final interpretation.
Characterisation of the Upper Respiratory Tract Virome of Feedlot Cattle and Its Association with Bovine Respiratory Disease
Authors: Ambrose Rebecca K. , Blakebrough-Hall Claudia , Gravel Jennifer L. , Gonzalez Luciano A. , Mahony Timothy J.
Published: February 2023

Bovine respiratory disease (BRD) is a major health problem within the global cattle industry. This disease has a complex aetiology, with viruses playing an integral role. In this study, metagenomics was used to sequence viral nucleic acids in the nasal swabs of BRD-affected cattle. The viruses detected included those that are well known for their association with BRD in Australia (bovine viral diarrhoea virus 1), as well as viruses known to be present but not fully characterised (bovine coronavirus) and viruses that have not been reported in BRD-affected cattle in Australia (bovine rhinitis, bovine influenza D, and bovine nidovirus). The nasal swabs from a case–control study were subsequently tested for 10 viruses, and the presence of at least one virus was found to be significantly associated with BRD. Some of the more recently detected viruses had inconsistent associations with BRD. Full genome sequences for bovine coronavirus, a virus increasingly associated with BRD, and bovine nidovirus were completed. Both viruses belong to the Coronaviridae family, which are frequently associated with disease in mammals. This study has provided greater insights into the viral pathogens associated with BRD and highlighted the need for further studies to more precisely elucidate the roles viruses play in BRD.
Identifying High-Risk Events for COVID-19 Transmission: Estimating the Risk of Clustering Using Nationwide Data
Authors: Ueda Minami , Hayashi Katsuma , Nishiura Hiroshi
Published: February 2023

The transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to be overdispersed, meaning that only a fraction of infected cases contributes to super-spreading. While cluster interventions are an effective measure for controlling pandemics due to the viruses’ overdispersed nature, a quantitative assessment of the risk of clustering has yet to be sufficiently presented. Using systematically collected cluster surveillance data for coronavirus disease 2019 (COVID-19) from June 2020 to June 2021 in Japan, we estimated the activity-dependent risk of clustering in 23 establishment types. The analysis indicated that elderly care facilities, welfare facilities for people with disabilities, and hospitals had the highest risk of clustering, with 4.65 (95% confidence interval [CI]: 4.43–4.87), 2.99 (2.59–3.46), and 2.00 (1.88–2.12) cluster reports per million event users, respectively. Risks in educational settings were higher overall among older age groups, potentially being affected by activities with close and uncontrollable contact during extracurricular hours. In dining settings, drinking and singing increased the risk by 10- to 70-fold compared with regular eating settings. The comprehensive analysis of the COVID-19 cluster records provides an additional scientific basis for the design of customized interventions.
Phage and Antibiotic Combinations Reduce Staphylococcus aureus in Static and Dynamic Biofilms Grown on an Implant Material
Authors: Joo Hyonoo , Wu Sijia M. , Soni Isha , Wang-Crocker Caroline , Matern Tyson , Beck James Peter , Loc-Carrillo Catherine
Published: February 2023

Staphylococcus aureus causes the majority of implant-related infections. These infections present as biofilms, in which bacteria adhere to the surface of foreign materials and form robust communities that are resilient to the human immune system and antibiotic drugs. The heavy use of broad-spectrum antibiotics against these pathogens disturbs the host’s microbiome and contributes to the growing problem of antibiotic-resistant infections. The use of bacteriophages as antibacterial agents is a potential alternative therapy. In this study, bioluminescent strains of S. aureus were grown to form 48-h biofilms on polyether ether ketone (PEEK), a material used to manufacture orthopaedic implants, in either static or dynamic growth conditions. Biofilms were treated with vancomycin, staphylococcal phage, or a combination of the two. We showed that vancomycin and staph phages were able to independently reduce the total bacterial load. Most phage-antibiotic combinations produced greater log reductions in surviving bacteria compared to single-agent treatments, suggesting antimicrobial synergism. In addition to demonstrating the efficacy of combining vancomycin and staph phage, our results demonstrate the importance of growth conditions in phage-antibiotic combination studies. Dynamic biofilms were found to have a substantial impact on apparent treatment efficacy, as they were more resilient to combination treatments than static biofilms.
Influence of Climatic Variables on Incidence of Whitefly-Transmitted Begomovirus in Soybean and Bean Crops in North-Western Argentina
Authors: Reyna Pablo , Suarez Franco , Balzarini Mónica , Rodriguez Pardina Patricia
Published: February 2023

Over the last 20 years, begomoviruses have emerged as devastating pathogens, limiting the production of different crops worldwide. Weather conditions increase vector populations, with negative effects on crop production. In this work we evaluate the relationship between the incidence of begomovirus and weather before and during the crop cycle. Soybean and bean fields from north-western (NW) Argentina were monitored between 2001 and 2018 and classified as moderate (≤50%) or severe (>50%) according to the begomovirus incidence. Bean golden mosaic virus (BGMV) and soybean blistering mosaic virus (SbBMV) were the predominant begomovirus in bean and soybean crops, respectively. Nearly 200 bio-meteorological variables were constructed by summarizing climatic variables in 10-day periods from July to November of each crop year. The studied variables included temperature, precipitation, relative humidity, wind (speed and direction), pressure, cloudiness, and visibility. For bean, high maximum winter temperatures, low spring humidity, and precipitation 10 days before planting correlated with severe incidence. In soybeans, high temperatures in late winter and in the pre-sowing period, and low spring precipitations were found to be good predictors of high incidence of begomovirus. The results suggest that temperature and pre-sowing precipitations can be used to predict the incidence status [predictive accuracy: 80% (bean) and 75% (soybean)]. Thus, these variables can be incorporated in early warning systems for crop management decision-making to reduce the virus impact on bean and soybean crops.
Development and Evaluation of a Novel One-Step RT-qPCR Targeting the Vero Gene for the Identification of False-Positive Results Caused by Inactivated Virus Vaccine Contamination
Authors: Zheng Xin-Qi , Yang Wan-Bao , Xie Lin , Wei Zi-Han , Zhuang Jiang-Xing , Yang Tian-Ci
Published: February 2023

To identify false-positive SARS-CoV-2 test results caused by novel coronavirus inactivated vaccine contamination, a novel RT-qPCR targeting the ORF1ab and N genes of SARS-CoV-2 and Vero gene was developed. The amplification efficiency, precision, and lower limit of detection (LLOD) of the RT-qPCR assay were determined. A total of 346 clinical samples and 132 environmental samples were assessed, and the diagnostic performance was evaluated. The results showed that the amplification efficiency of the ORF1ab, N, and Vero genes was 95%, 97%, and 93%, respectively. The coefficients of variation of Ct values at a concentration of 3 × 104 copies/mL were lower than 5%. The LLOD for the ORF1ab, N, and Vero genes reached 8.0, 3.3, and 8.2 copies/reaction, respectively. For the 346 clinical samples, our RT-qPCR assay identified SARS-CoV-2-positive and SARS-CoV-2-negative samples with a sensitivity of 100.00% and a specificity of 99.30% and novel coronavirus inactivated vaccine-contaminated samples with a sensitivity of 100% and a specificity of 100%. For the environmental samples, our RT-qPCR assay identified novel coronavirus inactivated vaccine-contaminated samples with a sensitivity of 88.06% and a specificity of 95.38%. In conclusion, the RT-qPCR assay we established can be used to diagnose COVID-19 and, to a certain extent, false-positive results due to vaccine contamination.
Recovering from the Unprecedented Backsliding in Immunization Coverage: Learnings from Country Programming in Five Countries through the Past Two Years of COVID-19 Pandemic Disruptions
Authors: Athiyaman Anithasree , Ajayi Tosin , Mutuku Faith , Luwaga Fredrick , Bryer Sarah , Giwa Omotayo , Mngemane Shadrack , Edwige Nnang Nadege , Berman Leslie
Published: February 2023

Between 2020 and 2021, the COVID-19 pandemic severely strained health systems across countries, leaving millions without access to essential healthcare services. Immunization programs experienced a ‘double burden’ of challenges: initial pandemic-related lockdowns disrupted access to routine immunization services, while subsequent COVID-19 vaccination efforts shifted often limited resources away from routine services. The latest World Health Organization (WHO) and United Nations Children’s Fund (UNICEF) estimates suggest that 25 million children did not receive routine vaccinations in 2021, six million more than in 2019 and the highest number witnessed in nearly two decades. Recovering from this sobering setback requires a united push on several fronts. Intensifying the catch-up of routine immunization services is critical to reach children left behind during the pandemic and bridge large immunity gaps in countries. At the same time, we must strengthen the resilience of immunization systems to withstand future pandemics if we hope to achieve the goals of Immunization Agenda 2030 to ensure vaccinations are available for everyone, everywhere by 2030. In this article, leveraging the key actions for sustainable global immunization progress as a framework, we spotlight examples of strategies used by five countries—Cambodia, Cameroon, Kenya, Nigeria, and Uganda—who have exhibited exemplar performance in strengthening routine immunization programs and restored lost coverage levels in the last two years of the COVID-19 pandemic. The contents of this article will be helpful for countries seeking to maintain, restore, and strengthen their immunization services and catch up missed children in the context of pandemic recovery and to direct their focus toward building back a better resilience of their immunization systems to respond more rapidly and effectively, despite new and emerging challenges.
The Effects of Economic Policy Instruments of Diffuse Water Pollution from Agriculture: A Comparative Analysis of China and the UK
Authors: Zou Jinpeng , Chen Xiaodong , Liu Fang , Wang Fang , Du Mingling , Wu Bin , Yang Ni
Published: February 2023

The world is facing the challenge of increasing grain production and improving the environment, in which the treatment of diffuse water pollution from agriculture is the important content. Traditional administrative means are still unable to solve the problem of market failure and government failure in controlling water pollution. Economic policy instruments have more advantages in improving market economics and reducing the cost of environmental governance and supervision. They have become an important way to solve pollution and promote the transformation of water pollution prevention and control management. This paper puts forward suggestions and countermeasures for improving China’s economic policy instruments by systematically sorting out and analyzing the EPIs in China and the UK. Starting from the whole process of agricultural production, China’s water quality governance needs to follow three principles to innovate and comprehensively utilize economic policy instruments. A transparent multi-party information sharing and an efficient supervision system are invisible to water quality governance. China also needs to continue to deepen reforms and pilot projects, especially in terms of governance objectives, public welfare funds, water prices, tradable water rights, and emission rights. This paper could also provide a reference for water pollution control in other developing countries.
Correction: Mahindawansha et al. Spatial and Temporal Variations of Stable Isotopes in Precipitation in the Mountainous Region, North Hesse. Water 2022, 14, 3910
Authors: Mahindawansha Amani , Jost Marius , Gassmann Matthias
Published: February 2023

In the original publication [...]
Comparative Analysis of Water Quality Applying Statistic and Machine Learning Method: A Case Study in Coyuca Lagoon and Tecpan River, Mexico
Authors: Avila-Perez Humberto , Flores-Munguía Enrique J. , Rosas-Acevedo José L. , Gallardo-Bernal Iván , Ramirez-delReal Tania A.
Published: February 2023

The water quality monitoring of lotic and lentic ecosystems allows for informing the possible use in human activities and the consumption of the vital liquid. This work measures the biochemical parameters in Coyuca Lagoon and Tecpan River, localized in Guerrero, Mexico. A comparative statistical analysis of six physicochemical factors in lentic and lotic ecosystems was carried out, finding individual pH values slightly higher for the lagoon ecosystem and lower for the river. For electrical conductivity, we find river sites with parameters lower than 500 μS/cm ideal for human use and consumption. On the contrary, in sites of the lagoon system, the conductivity was higher. As for the total hardness of the river, the values are within the Mexican standard; however, for the lagoon ecosystem, the water has a higher amount of calcium and magnesium salts and is not recommended for human consumption. For chlorides, the lagoon system exceeds the limits of regulations for human consumption; otherwise, it happens with the lotic system. The values of total alkalinity and total dissolved solids are higher for the lentic system than for the lotic one. Finally, the machine learning method shows the importance of measuring other parameters to determine the water quality, especially the salinity and calcium hardness.
Spatio-Temporal Analysis and Health Risk Assessment of Heavy Metals in Water from the Fuhe River, South China
Authors: Guo Xiaojuan , Xiao Yilong , Zhao Lanzhi , Yang Tao , Tang Chun , Luo Wei , Huang Cheng , Zheng Fangwen
Published: February 2023

With rapid developments in society and economy, the concentrations of heavy metals in surface water in South China have increased significantly, which poses a serious threat to the regional water security. In this study, the Fuhe River watershed in South China was selected as the study area to analyze physicochemical characteristics and heavy metal (Cu, Zn, Pb, Cd and Cr) concentrations in river water in the dry and rainy seasons, in 2019, with the purpose of exploring their spatial–temporal variations and main influences and assessing the potential health risks of heavy metals. The pH value of river water varied from 5.82 to 7.97, and it fluctuated less overall in the dry season, but it oscillated greatly in the rainy season and was lower, especially in the lower reach of the Fuhe River. The electrical conductivity (EC) value changed between 33 μS/cm and 128 μS/cm and increased and fluctuated along the river flow in the two periods. The concentrations of Cd, Cr, Cu, Pb, and Zn in river water showed obvious differences between the two periods. The concentrations of Cd and Cu were lower with the ranges from 0.001 μg/L to 0.67 μg/L and from 1 μg/L to 12 μg/L, respectively, in the dry season than in the rainy season, while there were inverse cases for other heavy metals. Along the river flow, the Cr concentration was stable, whereas other heavy metals showed increasing trends. It was noted that the concentrations of heavy metals in the Fuhe River were, on average, lower than the Chinese drinking standard values, with the concentration of Pb in the dry season significantly higher than the drinking standard value of the World Health Organization (WHO). Principal component analysis and correlation analysis showed that rock weathering and anthropogenic inputs were the main controlling factors of Cu and Zn in the Fuhe River, and human activities were mainly responsible for Pb, Cr, and Cd concentrations. The health risk assessment results showed that the non-carcinogenic risk (HQingestion) value of Pb was greater than 1 in most sampling points in the middle and lower reaches in the dry season, suggesting a significant non-carcinogenic risk for adults and children by direct ingestion. The minimum carcinogenic risk (CRingestion) value of Cr was more than 10−4 in the rainy and dry seasons, and the CRingestion value of Cd in some sampling points was more than 10−4 in the rainy season, indicating significant cancer risks to adults and children. For areas with significant pollution and health risks in the Fuhe River watershed, it is urgent to strengthen the controls of industrial, agricultural, and urban wastewater discharge.
Effectiveness of Nature-Based Solutions for Mitigating the Impact of Pluvial Flooding in Urban Areas at the Regional Scale
Authors: Hamers Eike M. , Maier Holger R. , Zecchin Aaron C. , van Delden Hedwig
Published: February 2023

Pluvial flooding causes significant damage in urban areas worldwide. The most common approaches to mitigating these impacts at regional scales include structural measures such as dams, levees and floodways. More recently, the use of nature-based solutions (NBS) is receiving increasing attention, as such approaches are more adaptive than structural measures and have a number of potential co-benefits (e.g., improvements in water quality and amenity). As NBSs are generally applied at house or block scales in urban areas, their potential for reducing the impacts of urban flooding at the regional scale are unknown. We introduce an approach that enables the potential of using portfolios of NBSs to reduce the impact of urban flooding to be assessed at the regional scale. This approach enables the most suitable locations for such portfolios of NBSs to be identified, as well as their effectiveness to be modeled at spatial resolutions that are commonly used for regional planning studies. The approach is applied to a case study area to the north of Adelaide, South Australia, with results obtained suggesting that there is significant potential for using strategically placed portfolios of NBSs to reduce the impact of pluvial flooding in urban areas at the regional scale.
Aspects of aocio-cultural transformation of the modern community of Ukrainian Azov region
Authors: Slyuschynskyi Bogdan ,   Mariupol State University
Published: February 2023

The article is devoted to the analysis and research of the current state of the community of the Ukrainian Azov region, which today is in a very tense situation due to hostilities in eastern Ukraine, and the Azov region in this case is a frontline territory. In addition, in any society there are continuous changes, which are caused by many factors. As you know, only three generations coexist together, which are already different from each other. Each generation receives its own level of culture, which comes to them from the period of life and state of society that surrounds them at the time of their birth and the beginning of their perception of the natural and social environment. Conflicts, that took place during the years of development of the Ukrainian state system and now in the period of settlement conflict and development of the world on East of Ukraine, that envisages a search and being of successful combination of interests, resources and their mobilization that can and must provide the protracted world, influence on socio-cultural transformation of modern society. Supposition is pulled out in research, that strengthening of possibilities of civil society on a way to the settlement of conflict on East of Ukraine it maybe to attain by means of dialogue and consolidation of civil organizations, and also leveling of forces, that harm peaceful. The article is conditioned by the search of methodological ways that would answer the requirements of time and newest realities of cultural development of modern Ukrainian society of the East region of Ukraine modern sociology. In fact problem of socio-cultural transformation of society during aspiring to acquisition the European standards them important enough. Today in this world there are different crisis situations and enormous changes that touch absolutely all spheres of human existence. Them not it maybe not to notice, but no longer to react those. Many scientists of contemporaneity try to investigate and analyze those changes that today take place not only in Ukraine but in the world in оn the whole. The aim of the article consists in the scalene review of modern problem of Ukrainian society, that is caused by socio-cultural transformation, integration influences of the European countries and different political, economic factors and crisis phenomena that today take place in the world and affects public relations of the Azov region.
Publication review History of Ukrainian culture (from ancient times to the XIX century): illustrated textbook. in 3 parts. / general. ed. prof. Yu. S. Sabadash. – Part 1. – Kyiv: Lira-k Publishing House, 2020. – 320 p.
Authors: Petrova Irina ,   Kyiv National University of Culture and Arts
Published: February 2023

The review analyzes an illustrated anthology on the history of Ukrainian culture. It is emphasized that this book is the first attempt in Ukrainian educational literature to present comprehensively the historical and cultural genesis of Ukraine from ancient times to the XIX century. It is noted that in the context of the modern orientation the domestic higher education is aimed at analyzing the phenomenon of Ukrainian culture and revising established views onto the perception of its phenomena, the issue of the announced anthology seems relevant to us. The review emphasizes the indisputable factual value and prospects of using the illustrated anthology on Ukrainian culture in institutions of higher education of Ukraine in the courses “History of Ukrainian culture”, “History of Ukraine”, “Ukrainian Ethnography”, “Traditional Culture of Ukrainians”, “History of Ukrainian Art”, “Cultural Studies”; in cultural, historical, ethnographic, local history studies; in museum, cultural and educational practices. Historical and cultural essays formulated for each of the five sections of the anthology, unique documentary and illustrative material are a significant basis for students’ successful assimilation of knowledge onto the history of Ukrainian culture. The textbook will be useful not only for students, but also for cultural workers and those who are interested in the culture of our nation.
Освітня складова державної політики у сфері культури в умовах інноваційного розвитку суспільства
Authors: Hololobov Serhii , Antonova Liudmyla
Published: February 2023

У статті здійснено теоретико-методологічне переосмислення ролі та значення освітньої складової державної політики у сфері культури в умовах інноваційного розвитку суспільства та надано практичні рекомендації щодо її удосконалення. Визначено та обґрунтовано що державна політика у сфері культури та її освітня складова сприяють якісному розвитку головного ресурсу держави – людського потенціалу. Розкрито роль та значення культурологічного аспекту освіти і запропоновано під ним розуміти цілеспрямований процес виховання та навчання, що спирається на трансляцію та відтворення цінностей культури, створених у процесі духовної, інтелектуальної, творчої діяльності людей та що відповідають цілям самореалізації людини та суспільства. Здійснено аналіз Закону України «Про культуру», за результатом якого визначено що його вплив поширюється на всі суспільні сфери та види і структури державної діяльності, зокрема і на галузь освіти. Розглянуто тріаду основних функцій (економічну, соціальну, культурну), які виконує освіта як соціальний інститут та визначено їх взаємозв’язок між собою. Обґрунтовано, що головною стратегічною метою державної політики у сфері культури у галузі освіти має стати формування духовних (освітніх, моральних, естетичних, художніх та ін.) якостей особистості здобувачів освіти, організація і безпосереднє проведення системної культурно-освітньої та виховної роботи з ними. Зроблено висновок що пріоритетним завданням державної політики у сфері культури у галузі освіти має постати сприяння гуманістичній спрямованості усіх видів освітньої та виховної діяльності. Доведено тезу відносно того, що на сучасному етапі розвитку українського суспільства перед державною політикою у сфері культури у галузі освіти постають принципово нові завдання підготовки здобувачів освіти, зокрема – підготовки здобувачів вищої освіти (розкрито їх суть та запропоновано рекомендації щодо основних напрямів їх реалізації). Визначено основні тенденції якими характеризується сучасна державна політика у сфері культури у галузі освіти: віртуалізація; персоналізація; керована ініціативність; практична користь і короткостроковість. Описано трансформацію освітньої складової державної політики у сфері культури та закладів вищої освіти культурно-мистецького профілю в умовах збройної агресії Російської Федерації проти України.
Політична коректність – соціальний конструкт сучасного мовного простору публічного управління
Authors: Yemelyanov Volodymyr , Yevtushenko Natalia
Published: February 2023

У статті розглянута політична коректність, як соціальний конструкт повсякденного сучасного політкоректного мовного простору публічного управління, що була запропонована і розроблена у 60-х рр. ХХ століття Пітером Бергером і Томасом Лукманом.
Доведено, що в публічному управлінні в умовах комунікації, дотримання політкоректності спрямоване на те, щоб знайти нові способи мовного вираження замість тих, які торкаються почуттів та гідності окремої людини, стосовно раси, статі, віку, стану здоров’я, соціального статусу, зовнішнього вигляду та ін.
Зазначено, що політкоректність, як нормований мовний спосіб поведінки, притаманний будь-якому суспільству, зокрема українському, тому що пов’язаний з моделями коректної поведінки членів суспільства, а з точки зору теорії соціального конструктивізму має певний потенціал конструювання уявлень про реальність життя населення.
Підкреслено, що уявлення про політкоректність, як соціальний конструкт публічного управління засновано на тому, що люди в суспільстві засвоюють загальну точку зору щодо більшості речей, що існують в суспільній свідомості, як частину наданої  соціальної реальності, що існує об’єктивно, але завжди є суб’єктивною тому що формується, інтерпретується, конструюється акторами в процесі комунікації.
Визначено, що політкоректність, як надана нам реальність і водночас конструкт соціальної реальності, створюється, конструюється та засвоюється людьми у вигляді політкоректних цінностей і норм, для того щоб в процесі комунікації, утримуватися від висловів, поглядів і дій, які можуть бути образливими для інших членів суспільства. Політкоректність є формою соціальної організації, що конструюється на суб’єктивних знаннях людей в процесі їх діяльності, та є символічною структурою, що інтегрована в модель політкоректної мовної поведінки.
В подальших дослідженнях пропонується вивчення політкоректності через механізми активного залучення громадськості до процесів публічного управління, зокрема об’єднаних територіальних громад.
Державна політика цифрового розвитку сфери музейної справи французької республіки: досвід для України
Authors: Oryshchuk Vasyl
Published: February 2023

Метою статті є висвітлення державної політики цифрового розвитку сфери музейної справи Французької Республіки.
Теоретичну основу становлять праці науковців, дослідження веб-сайтів Міністерства культури Французької Республіки, французьких культурних інституцій, ознайомлення з нормативно-правовими документами.
Праці науковців охоплювали: здійснення комплексного критичного аналізу законів і політики, які стосуються культурної спадщини по всій Європі, розглядаючи їх у світлі сучасних викликів, з якими стикається Європейський Союз; виокремлення важливості подальшого дослідження розвитку цифрових інфраструктур до 2030 року України спираючись на досвід Французької Республіки та інших європейських держав; належного врядування, яке є одним з основних факторів конкурентоспроможності держави, розвитку її економіки та передумовою європейської інтеграції.
Методологічною основою дослідження є комплекс прийомів, спрямованих на узагальнення та систематизацію аналізу матеріалу.
У статті досліджено децентралізаційні процеси та етапи цифровізації в музейних інституціях Франції, виокремлено три місії, які покладені на музеї Франції щодо оцифрування та онлайн публікація музейних колекцій, проаналізовано пріоритети цифрового поширення колекцій музеїв у Франції тощо.
Розкрито основні засади державної політики цифрового розвитку у сфері музейної справи Французької республіки. У питаннях оцифрування та цифровізації в музейних інституціях і цифрового розповсюдження колекцій в мережі «Інтернет».
Робота покликана продемонструвати теоретичні аспекти процесу поширення цировізації та взаємодії органів влади та музейних інституцій. Ключовим аспектом є виокремлення напрямку дослідження теми, а саме цифровізаційних процесів, застосування та їх керівництво.
Правові аспекти відповідальності у сфері порушення прав інтелектуальної власності: світовий досвід і Україна
Authors: Shtyrov Oleksandr , Sukhorukova Anna
Published: February 2023

У статті проаналізовано основні етапи становлення поняття «авторське право» як невід’ємної складової інтелектуальної власності. Досліджено міжнародний досвід юридичної відповідальності за порушення прав інтелектуальної власності. Зазначено що в нашій державі не створено досі таких умов для суб’єктів прав інтелектуальної власності, за яких вони б могли бути впевнені у захищеності та непорушності результатів своєї розумової діяльності. Акцентовано увагу на тому що авторське право проявляється одним із важливих інститутів права інтелектуальної власності, який регулює суспільні відносини, пов'язані зі створенням творів науки, літератури і мистецтва, розпорядженням винятковим правами на ці твори, а також захистом виняткових і інших прав автора і його правонаступників і інших правовласників. Показано що взаємовідносини України та ЄС у сфері захисту прав інтелектуальної власності відбуваються у форматі діалогу який проходить у форматі спільних засідань, де розглядаються питання захисту прав інтелектуальної власності, боротьби з порушеннями, примусового ліцензування тощо, організації спільних зустрічей на рівні експертів.
Згідно наявних даних досліджень Property Rights Alliance показник індексу прав власності в Україні так званий Міжнародний індекс прав власності (IPRI) є надто низьким у порівнянні із країнами ЄС.
Зроблено висновок проте що проблема захисту прав інтелектуальної власності є міжнародною, а тому світова спільнота зосереджує свої зусилля та здійснює активну політику щодо забезпечення належного рівня захисту інтелектуальних прав людини, через створення ефективного правового механізму захисту прав інтелектуальної власності. Світовий досвід виступає важливим позитивним інструментом, здійснюючи його аналіз можна знайти необхідні ключові шляхи для реформування законодавства в сфері інтелектуальної власності в Україні.
Публічне управління захистом національних цінностей в зарубіжних країнах в умовах повномасштабної російсько-української війни
Authors: Larin Stanislav
Published: February 2023

Метою статті є теоретичний аналіз публічного управління захистом національних цінностей у зарубіжних країнах з метою адаптації їх позитивного досвіду в Україні. Предметом дослідження є комплекс принципів, методів та наукових підходів публічного управління захистом національних цінностей, які використовуються в європейських країнах.
Методологічною основою статті є теоретичний аналіз принципів, методів та наукових підходів публічного управління захистом національних цінностей зарубіжних країнах, їх реалізація в умовах повномасштабної російсько-української війни
В статті автором зазначено, що декларація європейської ідентичності базувалася на спільній спадщині, в основу якої покладено такі цінності: ідентичне ставлення до життя, сформоване на ідеї створення суспільства відповідно до потреб людей; принципи результативної демократії; рівність перед законом; соціальна справедливість і повага до людських прав. Для вступу до європейської спільноти Україні потрібно адаптувати ці цінності і вибудувати цивілізований захист національних цінностей Української держави, особливо в умовах глобалізаційних викликів та трансформаційних змін.
Доцільно скористатися досвідом захисту національних цінностей Німеччини, Франції чи Великої Британії для розбудови України саме у тих аспектах, які сприймаються українським суспільством і державою. Автор вважає, що серед пріоритетних європейських досягнень важливими для імплементації в Україні є такі: збереженн безпеки на європейському континенті в умовах російської агресії, підвищення рівня самосвідомості громадян держави щодо сприяйняття ними України як частини Європейського Союзу, розвиток громадянської освіти.
Позитивний досвід таких європейських держав як Велика Британія, Німеччина та Франція щодо публічного управління захистом національних цінностей може бути адаптований в Україні на засадах європейської безпеки, міжнародного партнерства, сприяти наближенню перемоги України у повномасштабній російсько-українській війні над загарбником.
The Incidence of Moderate and Severe Ovarian Hyperstimulation Syndrome in Hospitalized Patients in China
Authors: Zheng Danni , Shi Ying , Wang Yuanyuan , Li Rong , Long Xiaoyu , Qiao Jie
Published: February 2023

Background

Ovarian hyperstimulation syndrome (OHSS) occurs in women receiving fertility treatments. Moderate and severe OHSS cases are required to be admitted to hospital for treatment. The incidence of moderate and severe OHSS and the characteristics of these cases are unknown in China. We aimed to assess the incidence of moderate and severe OHSS in national databases from China between 2013 and 2017.

Methods

We extracted moderate and severe OHSS cases from the Hospital Quality Monitoring System, the nationwide inpatient data collection system. We used ovum pick-up (OPUbaidu) cycle data from the annual report of China’s National Health Commission, developed on the basis of OPU data collected by National ART Management Information System. Overall incidence of moderate and severe OHSS (women aged 20 to 50 years) and year-specific incidence by each calendar year in China were calculated. We also investigated the age distribution in OHSS and OHSS with different comorbidities.

Results

We extracted 18,022 eligible patients with moderate or severe OHSS and 1,581,703 OPU cycles. The overall incidence of moderate and severe OHSS between 2013 and 2017 was 1.14%. The year-specific moderate and severe OHSS incidence was 1.1% in 2013, 1.4% in 2014, 1.4% in 2015, 1.1% in 2016, 0.9% in 2017, respectively. Women aged 26 to 30 years accounted for 48.4% of OHSS cases, followed by women aged 31 to 35 years (30%) and 20 to 25 years (14.2%). The age distribution pattern was consistent across OHSS with different comorbidities.

Conclusions

This study reported the incidence of moderate and severe OHSS in China using nationwide data for the first time. Our findings support that women aged under 35 years receiving assisted reproductive technology need more attention than other age groups in terms of OHSS risk control.
Enhanced vitamin B12 production using paneer whey as culture medium
Authors: Gopalakrishnan Sangavi , Rajkumar Harini , Antony Usha , B.S Lakshmi , Ganesan Nandhini Devi
Published: February 2023

Vitamin B12, a water-soluble vitamin, plays a vital role in regulating metabolism in many organisms. However, its synthesis is restricted to limited bacteria and archaea. Therefore, industrial microbial fermentation is considered as a robust method to meet the demands of the vitamin B12. Lactobacillus reuteri DSM 20016 is one of the vitamin B12 producers. In the present study, liquid paneer whey is used as the medium along with the supplements, glycerol, and cobalt chloride to enhance the vitamin B12 production. The effect of liquid paneer whey, yeast extract, glycerol, and cobalt chloride on the vitamin B12 production was further optimized using Box Behnken design. Under optimized conditions, the production of the vitamin B12 reached up to 213.449 μg.L-1. The current study validated the feasibility of utilizing liquid paneer whey as a medium to produce high yield vitamin B12 by Lactobacillus reuteri DSM 20016.