bluuebunny/crossref_metadata_2025 huggingface dataset:
Distribution of compound potentials recorded from the surface of isolated stellate ganglia following stimulation of postganglionic branches, in rats and cats
Authors: Kukuła Krzysztof , Szulczyk Paweł , Urbanowicz Arkadiusz
Published: December 2023

The experiments were performed on 9 cat and 18 rat isolated stellate ganglia. Rats and cats were anesthetized with alpha-glucochloralose or urethane, respectively. The ganglia, isolated with their branches, were transferred to a recording chamber and constantly superfused with artificial extracellular fluid bubbled with 95% O2 and 5% CO2. Branches of the ganglion were one by one placed in suction electrodes and stimulated. Antidromic evoked potentials were systematically recorded from numerous points on the ganglion surface. The area under the curve of the negative wave of each recorded potential was considered proportional to the number of neurons located in the vicinity of the recording electrode, projecting to the stimulated nerve. We have found that: (1) cardiac sympathetic neurons are located in the lower, caudal half of the ganglia; (2) vertebral sympathetic neurons occupy the cranial, upper half of the ganglia; (3) neurons with axons in the ansae are positioned near the point of exit of the respective ansa from the ganglion; (4) localization of neurons projecting to the same branches is very similar on both sides – right and left; (5) this localization is also similar in rats compared to cats.
Effect of palmitoylcarnitine on the cellular differentiation, proliferation and protein kinase C activity in neuroblastoma NB-2a cells
Authors: Nałęcz Katarzyna , Mroczkowska Joanna , Berent Urszula , Nałęcz Maciej
Published: December 2023

Palmitoylcarnitine is synthesized through the action of palmitoylcarnitine transferase I – an enzyme specifically inhibited by etomoxir. An increase of the intracellular content of palmitoylcarnitine in neuroblastoma NB-2a cells after administration of carnitine was correlated with an inhibition of cell proliferation and a concomitant promotion of differentiation processes. The activity of protein kinase C was measured in vivo, with cells permeabilized through the use of streptolysin O and a peptide substrate. Palmitoylcarnitine inhibited the phorbol ester stimulated reaction of the peptide phosphorylation in a concentration dependent way. The degree of protein kinase C inhibition was correlated with intracellular increase of the palmitoylcarnitine content, pointing to this compound as a natural modulator of protein kinase C activity.
Activation of reward-relevant neurons in the caudate-putamen influences the development of medial prefrontal cortex self-stimulation: a moveable electrode mapping study
Authors: Bielajew Catherine , Trzcińska Monika
Published: December 2023

Two hundred fifty five medial prefrontal cortical (MPFC) and 187 caudate-putamen (CPu) sites were evaluated for intracranial self-stimulation in 67 animals using moveable electrodes and collecting trade-off functions between current and frequency. Eleven percent of the examined areas, located predominantly in the ventromedial aspects of MPFC and CPu, showed reliable self-stimulation and the average charge of 1.12 and 1.11 microC respectively, values that are in line with those reported for the Medial forebrain bundle. The distribution of charge, however, was greater than reported for the latter region, and ranged between 0.68 to 1.63 microC across sites. Some subjects were implanted with two electrodes, one aimed at the MPFC, and the other at the CPu, ventral tegmental area, or lateral hypothalamus. Only animals with CPu placements showed transference of self-stimulation to the MPFC, suggesting that these two regions might form part of the same reward substrate, a view that has anatomical, electrophysiological and recently behavioral support.
Altered electrophysiological pattern of target detection in schizophrenia in the Continuous Attention Test
Authors: Basińska Anna
Published: December 2023

Visual evoked potentials were examined in 50 male schizophrenic patients and 50 age-matched healthy male volunteers during performance of the Continuous Attention Test (CAT). In the patients emerged an evident deterioration of attentional processes: much higher index of errors and longer reaction time than in the healthy subjects. On the other hand, in patients the following alterations in evoked potentials were found: (1) in the non-target condition lower amplitudes of components: left-sided P1, bilateral NI1as well as frontal P3a; (2) a distinct electrophysiological pattern of target detection, consisting of an increase in amplitudes of either N1 or P3a as compared to the response to the non-target stimulus. Electrophysiological features were related to behavioural data. An increase in the amplitude of N1 during detection of the target, as well as a lower non-target amplitude of P3a, correlated with poor CAT performance, while an increase in the amplitude of P3a during detection of the target correlated with relatively shorter reaction time, and showed no correlation with an index of errors. The results suggest an underlying primary hyperarousability at lower stages of visual data processing (up to N1 latency range) accompanied by several secondary pathological and compensatory mechanisms at the higher stages.
Insulin impairs the anticonvulsive activity of carbamazepine against maximal electroshock-induced seizures in mice
Authors: Alaraj Mohd , Pieniak Małgorzata , Kowalczyk Marek , Kosińska Irena
Published: December 2023

In view of the data indicating that insulin can modify penetration of some drugs across cell membranes and tissue barriers, particularly the blood-brain barrier, the aim of the present study was to evaluate the effect of insulin on both the anticonvulsant activity and the brain concentration of carbamazepine in mice suffering from seizures induced by maximal electroshock. The antiepileptic drug was administered per os in single doses either alone or in combination with insulin given as single intraperitoneal injections. To assess the anticonvulsant activity of carbamazepine the ED50 values were calculated. The results indicate that insulin given in doses up to 2 units/kg did not affect the convulsive threshold, whereas insulin applied at 2 units/kg led to a significant reduction in the anticonvulsant activity of carbamazepine, as judged by an increase in the ED50 value from 16.2 to 41.3 mg/kg. This effect was accompanied by the marked reduction in both the brain and blood concentrations of the drug. It is likely, therefore, that the inhibitory activity of insulin on the anticonvulsive function of carbamazepine is related not only to the effect of the former on the blood-brain transport of the latter, but also to insulin-induced modulation of the serum concentration of the drug.
Física experimental: a utilização de transistores em experimentos fotovoltaicos de baixo custo
Authors: De Sousa Neto Floriano Pedro , Do Rosario Samuel Antonio Silva
Published: December 2023

Neste estudo, investigamos o potencial de transistores comuns como substitutos de baixo custo para células fotovoltaicas convencionais em um contexto educacional. O objetivo era tornar o ensino de física mais interativo, demonstrando práticas de conversão de energia solar em elétrica. Utilizando uma metodologia experimental, desencapsulamos transistores para revelar as junções semicondutoras p-n e os expusemos à luz solar para gerar corrente contínua. A eficácia das células fotovoltaicas improvisadas foi testada individualmente e em série, enfatizando a adição de tensão em circuitos conectados em série e a produção de corrente contínua sob iluminação solar. Os resultados confirmam que os transistores podem efetivamente converter energia solar em corrente contínua, adequada para alimentar dispositivos de baixa tensão, e destacam a relevância de métodos experimentais no ensino de conceitos relacionados à energia renovável. O estudo conclui que a abordagem proposta não apenas aprimora o entendimento teórico dos alunos sobre semicondutores e tecnologia fotovoltaica, mas também promove a aplicação de conhecimentos em contextos práticos, contribuindo assim para a inovação no ensino de ciências.
Eventos que impactam a Effective Tax Rate (ETR)
Authors: Lima Emanoel Marcos , Lima Jessica de Morais
Published: December 2023

A adoção das normas internacionais de contabilidade pelo Brasil, além de provocar mudanças na legislação contábil, tributária e no cotidiano das empresas, apresenta diferenças no reconhecimento de receitas e despesas em relação ao critério estabelecido pela legislação tributária, provocando, dessa forma, diferenças na base de cálculo do Imposto de Renda e Contribuição Social e, por consequência, no valor e na alíquota efetiva dos tributos. A alíquota efetiva dos tributos, apurada com base no lucro contábil antes dos tributos, é denominada na literatura como Effective Tax Rate (ETR) e tratada por muitos estudos como uma medida de agressividade fiscal. Face as questões apresentadas, este trabalho tem por objetivo identificar os eventos que impactam a ETR, bem como refletir sobre a ETR como medida de agressividade fiscal. Para tanto, com base em estudos sobre a ETR, escolhas contábeis, legislação contábil e tributária, foi feita uma análise da apuração do Imposto de Renda e Contribuição Social, referente ao exercício de 2017, de duas empresas de capital aberto listadas na Bolsa de Valores de São Paulo (B3). A estratégia de pesquisa utilizada foi a análise de conteúdo, a fim de levantar um estudo qualitativo sobre as informações divulgadas. Os resultados do estudo apontam que a empresa Sabesp apresentou no período analisado, ou seja, em 2017, ETR de 28,09%, enquanto que a empresa Metal Leve apresentou ETR de 16,89%, e que a diferença apresentada pelas empresas em relação à alíquota nominal de 34% refere-se ao pagamento de Juros sobre Capital Próprio e Diferenças Permanentes.
How does a biopolymer (protein) fold into a unique 3D structure?
Authors: Shaitan K.V.
Published: December 2023

The current state of the problem of folding proteins and other biopolymers is discussed. The
concept of a multidimensional potential energy surface and a free energy surface for linear
polymers is detailed, taking into account the topology of the configuration space and the
presence of symmetry elements with respect to the permutation of identical monomer units. The
presence of kinematic bonds for conformational movements in a viscous medium leads to a
tendency to form helical structures of linear polymers. The dynamic effects of viscosity also lead
to an almost uniform distribution of energy dissipation rates over the chain nodes. The
combination of potential energy surface topography and viscosity effects provides a physical
basis for the development of the theory of folding in the direction of interpreting various
experimental observations and elucidating the principles for the formation of an amino acid
code for 3D protein structures. The relationship between the denaturation temperature of the
folded state of the biopolymer and the energy of non-valent interactions between monomers in
the chain is analyzed.
Perkembangan Pasar Tradisional Pancur Batu di Deli (1960-1975)
Authors: Sembiring Eva Angelia , Pujiati  , Zuska Fikarwin
Published: December 2023

This research uses a historical method consisting of heuristic stages, verification, interpretation and historiography, and uses a socioeconomic approach to explain chronologically the presence of the Pancur Batu market which then brings its development and influence on the welfare of the local community. The results showed that Pancur Batu Market was present since its area became part of the Deli tobacco plantation area centered in East Sumatra in 1872. The development was even more crowded in 1960 when a proposal was made by local residents to the regional government of Deli Hulu regarding the construction and expansion of the Pancur Batu market area in the form of adding stalls and los. In addition, the development of the Pancur Batu Market then has a significant influence on the negative direction in the form of traffic congestion because the Pancur Batu area is a link between the highlands and low flats and the condition of market waste is increasing, but from the positive side, there is a harmony of inter-ethnic relations in Pancur Batu and the increasing income of the population.
Keywords: Pancur Batu, distribution of goods, market influence
Fe3O4 nanoparticles decorated reduced graphene oxide&carbon nanotubes-based composite for sensitive detection of imatinib in plasma and urine
Authors: Naderi Nasim , Sabeti Bahare , Chekin Fereshteh
Published: December 2023

In this study, a new reduced graphene oxide (rGO) has been synthesized via a facile and envi­ronmentally friendly process using Callicarpa maingayi leaf extract. A novel magnetic catalyst based on Fe3O4 nanoparticles-reduced graphene oxide&carbon nanotubes ((Fe3O4--(rGO&CNT)) was prepared and characterized by hydrothermal method. The Fe3O4 nanoparticles with an average size of 25 to 40 nm were placed on carbon nanotubes and reduced graphene oxide sheets, while carbon nanotubes inserted between the reduced graphene oxide sheets effectively prevented their aggregation. The (Fe3O4-(rGO&CNT) composite has a large surface area and good electrocatalytic properties, suiting for the detection and determination of imatinib (IM) anticancer drug by voltammetry method. Under opti­mi­zed conditions, good linearity was achieved in the concentration range of 0.1 to 40 μmol L-1 and the limit of detection and sensitivity were 57 nmol L-1 and 3.365 μA L μmol-1, respectively. Furthermore, the fabricated sensor demonstrated acceptable reproducible behaviour and accuracy and a high level of stability during all electrochemical tests. In addition, the proposed method was applied for the detection of IM in biological samples and the recoveries were 94.0 to 98.5 %, with relative standard deviations of 2.1 to 4.4 %.
Causal microeconometrics in accounting research
Authors: Gruszczyński Marek
Published: December 2023

Purpose: This paper reviews accounting research that employed causal inference methodology, with a focus on methods associated with causal microeconometrics (quasi-experimental). The reviewed papers were published in five leading accounting journals from 2017 through 2021. Methodology/approach: The research approach is a literature review of studies that apply the methodology of causal microeconometrics to accounting. The main section of the paper describes five methods: the treatment effects approach, propensity score matching, natural experiment, difference-in-differences estimators, and regression discontinuity design. The assumptions and limitations of each method are discussed, and selected examples of causal inference published in five leading accounting journals are provided. Findings: The study confirms the increasing frequency of the use of causal inference methodologies in accounting research. Sometimes referred to as quasi-experimental or causal microeconometric, these methods can provide a base for finding evidence of causality. However, there are limitations associated with each method. Practical implications: Statistical-econometric methodology in accounting research based on regression is rarely able to demonstrate causal relationships. This paper presents the pros and cons of applying causal inference methodologies in accounting. Originality/value: The paper’s value lies in: (1) introducing to the research community the growing presence of quasi-experimental causal methodologies in accounting, (2) presenting causal research in accounting using causal microeconometric methods, (3) identifying papers using these methods that were published in five leading accounting journals between 2017 and 2021, and (4) highlighting the challenges and the need for caution and due consideration in applying these methods.
OS DESAFIOS DO USO DO TORNIQUETE NO ATENDIMENTO PRÉ-HOSPITALAR
Authors: De Sales Lorrana Barbosa , Da Silva Rennan Rodrigues Nunes , Pacheco Camila Aquino , De Lima Nayara Brenda Batista , Carvalho Marcílio da Costa , Lopes Graciana de Sousa
Published: December 2023

Descrever os desafios do uso do torniquete no atendimento pré-hospitalar e compreender a forma correta para o emprego do torniquete no atendimento pré-hospitalar e sua eficácia no controle de hemorragias massivas. A proposta desta revisão integrativa surge do anseio de ampliar o conhecimento de publicações relacionadas ao tema “os desafios do uso do torniquete no atendimento pré-hospitalar”. Para coleta de dados foram utilizadas as bibliotecas virtuais de pesquisa: Biblioteca Científica Eletrônica Online (SCIELO) e Literatura Latino Americana e do Caribe em Ciências da Saúde (LILACS) mediantes os descritores: “torniquetes”, “hemorragia” e “atendimento pré-hospitalar. Para que os dados fossem coletados, utilizou-se de bibliotecas virtuais para pesquisa: Biblioteca Científica Eletrônica Online (SCIELO) e Literatura Latino Americana e do Caribe em Ciências da Saúde (LILACS) com uso dos descritores: “torniquetes”, “hemorragia” e “atendimento pré-hospitalar”. Para constituir a pesquisa foram escolhidos trabalhos originais, dispostos de forma gratuita, escritos nos idiomas português e inglês, submetidos no período de 2013 a 2023, que tratam do tema pesquisado. Para definir a exclusão foram: Pesquisas em que os textos não estavam completos, resumos, dissertações de mestrado e teses de doutorado. Os artigos foram selecionados com base nos critérios de elegibilidade e inelegibilidade com base nos títulos, em seguida, os resumos foram analisados e, finalmente, os artigos foram lidos na íntegra e uma ferramenta foi criada para coletar informações diretamente das bases de dados. A velocidade e a eficácia do emprego de um torniquete em cenas de trauma, é capaz de ser a diferença entre a vida e a morte de uma vítima. Embora possua complicações inerentes ao seu uso incorreto, a ferramenta mostra inúmeras indicações e recomendações para uso oriundas de renomadas instituições como National Association of Emergency Medical Technicians (Associação Nacional dos Técnicos em Emergências Médicas) InternationalFederation of Red Cross (Federação Internacional da Cruz Vermelha).
Decision Support System for Poor Student Aid Recipients Using the Analytical Hierarchy Process (AHP) Method
Authors: Ratnawati Heri , Iskandar Akbar , Ahmed Abdulmajeed  , Haryanto  , Ridha Nur Ilahi
Published: December 2023

The enforcement of mandatory education programs facilitates funding for primary and secondary schools, aligning with legal provisions designed to boost student engagement. Nevertheless, a stark reality persists, with numerous children unable to attend school, leading to dropouts and an inability to progress. A key factor contributing to this issue is the School Operational Assistance (BOS) not covering essential educational costs like uniforms, books, and shoes. The challenge lies in identifying suitable recipients for Poor Student Aid, hindered by insufficient categorized support data. Addressing this, a targeted solution involves designing a system, utilizing the Analysis Hierarchy Process (AHP) Method. Decisions regarding poor student aid approval would then be grounded in rational, objective considerations. Proactively implementing a structured decision support system is crucial in assigning significance to criteria values and weights, tailored to SD Negeri Baddoka Makassar's needs. Through AHP, the selection process becomes more transparent, measurable, and accountable. The resulting decisions have the potential to enhance the efficiency of providing assistance to those genuinely in need.
Learners’ reception of translanguaging as a model for reading English L2 texts
Authors: Mabena Mampoi Irene
Published: December 2023

Language is the mediator of two critical aspects of a child's education: identity and knowledge. Through language, learners can make sense of who they are and make sense of the world around them. However, the teaching of English second language in several schools in South Africa is such that a learner's identity, best described in their own indigenous languages, is not mirrored in the classroom and, in its place, a monolingual system (English-only) becomes central. Their acquired linguistic repertoire as multilingual learners is considered a hindrance to learning, not a resource. This paper assesses learners’ reception of translanguaging pedagogy as a model for reading English texts. It further seeks to take the debate about the paradox of translanguaging forward to determine if translanguaging is a unitary, differentiated system, or both. Exploring data in the form of class observations and interviews, the study reveals that translanguaging as a model for reading English L2 texts is well-received by learners as a practical and valuable pedagogical approach that can potentially improve English L2 performance. The results further establish the existence of both the unitary and the differentiated systems of translanguaging. In the end, the study's recommendations for transforming multilingual classrooms are discussed.
Cellular Immunity in Individuals Classified by Antibody, After COVID-19 Infection/Vaccine
Authors: Yılmaz Niyazi Samet , Öztürk Reyhan , Şen Bayram , Ulukanlıgil Mustafa
Published: December 2023

Amaç: Koronavirus hastalığında (COVID-19), antikor ölçümü tek başına yetersiz veri sağlamasına rağmen, aşılama veya hastalığa karşı immün yanıtı değerlendiren çalışmalar hümoral immüniteye odaklanmıştır. Aşılama veya hastalıktan sonra humoral ve hücresel tepkiler benzer olmayabilir. Bu çalışmada, COVID-19 geçiren bireyler (CRI) ve aşılanmış sağlık çalışanları (VHCW), SARS-CoV-2 spike antijenine karşı immünoglobulin G (IgG) seviyelerine göre iki gruba ayrıldı, ardından interferon- gama (IFN-y) ile hücresel bağışıklık değerlendirildi.
Gereç ve Yöntem: CRI grubu (n=30) COVID-19 geçiren ve aşılanmamış bireylerden oluşmaktaydı. VHCW grubu (n=47) ise iki doz CoronaVac aşısı uygulanmış ve enfeksiyon geçirmemiş kişiler içermekteydi. VHCW grubunda, aşılamadan bir ay sonra humoral yanıt ve IFN-γ değerlendirilirken, COVID-19 geçiren hastalardan enfeksiyondan sonraki bir ay ile bir yıl arasında kan örnekleri alındı.

Bulgular: VHCW grubunda, IgG<7 ve IgG≥7 alt gruplarında IFN-γ (p=0.848) ve yaş (p=0.949) benzerdi. VHCW grubunda IFN-γ ve IgG düzeyleri arasında korelasyon saptanmadı (p=0.711). CRI grubunda, IFN-γ ve yaş, IgG≥7 alt grubunda daha yüksekti (sırasıyla p=0.005, p<0.001). CRI grubunda IFN-γ ve IgG arasında istatistiksel olarak anlamlı bir korelasyon yoktu; bununla birlikte bir trend görüldü (p=0.057, r=0.35). VHCW ve CRI grupları arasında IgG düzeyleri açısından fark saptanmadı; IFN-γ ise CRI grubunda daha yüksekti (p<0.001).

Sonuç: COVID-19'a karşı immün yanıtın gösterilmesi, aşıların ve terapötik ajanların geliştirilmesi için önemlidir. Pandemilerde halk sağlığını ilgilendiren kararlar alınırken aşı uygulamaları sonrasındaki hücresel yanıtı (T hücresi yanıtı) değerlendirmek değerlidir.
Actividades lúdicas de aprendizajes en niños con dislexia en la básica elemental
Authors: Demera Lucas Carmen Guadalupe , Vera García Luis Alfredo
Published: December 2023

Las actividades lúdicas son de vital importancia en el aprendizaje de niños con dislexia en la básica elemental, porque nos ayudan a resolver problemáticas que se presentan al no contar con acciones o programas dirigidos a mejorar las habilidades académicas. El objetivo planteado es implementar actividades lúdicas de aprendizajes en los niños que presentan dislexia en la básica elemental de la Escuela Santa Marianita de Jesús de la parroquia Charapotó, cantón Sucre. Se asumió un enfoque mixto para una investigación descriptiva, donde se utilizó métodos como: revisión bibliográfica, encuesta y entrevista, con un tipo de muestreo no probabilístico a conveniencia, basado en el juicio personal del investigador, con una población de 111 estudiantes de básica elemental, tomando una muestra de 45 estudiantes que corresponden al segundo año paralelos A y B, sin embargo, por la edad de ellos se hace la encuesta a sus padres y 3 docentes que laboran en la institución. Entre los principales resultados se encontró el desconocimiento del profesorado en la identificación y aplicación de técnicas e instrumentos para la detección de necesidades educativas, también fue evidente la poca participación de los padres de familia, siendo indispensable incluir en las instituciones procesos que permitan una intervención eficaz ante las dificultades en el aprendizaje.   Se concluye que se debe implementar actividades de capacitación a docentes y padres de familia sobre actividades con técnicas metodológicas para un óptimo desempeño dentro y fuera del aula de clases, logrando así el bienestar de los educandos y contrarrestar las dificultades que se presentan.
Սուրբ Ներսէս Շնորհալու «Հաւատով խոստովանիմ» աղօթքը. թարգմանութիւն եւ մշակութային փոխանցում
Authors: ԳԱՍՊԱՐՅԱՆ ԼՈՒԻԶԱ
Published: December 2023

Религиозно-философские труды Св. Нерсеса Шнорали (Нерсес Благодатный) всесторонне изучены десятками ученых и переведены на разные языки мира (более 36), занимая достойное место в мировой литературной и культурной сокровищнице. Целью исследования выступает выявление культурного трансфера в сравнительном ключе на материале переводов (русский, английский, итальянский) молитвы «С Верою Исповедую» Св. Нерсеса Шнорали. Очевидно, что молитва имеет уникальную текстовую структуру, в которой Св. Нерсеса Шнорали представляет двадцать четыре молитвы на каждый час дня. В статье всесторонне освещены структурные и стилистические особенности молитвы, языковые и вне-языковые факторы переводческой деятельности, а также некоторые стратегические принципы трансфера. Обозначается спектр вопросов, связанных с изучением специфики перевода религиозно маркированных единиц в свете парадигмы культурного трансфера. Методологическая основа статьи является концепция культурного трансфера, метод обратного перевода и традиционные для сравнительного литературоведения методики сопоставительного, текстологического и контекстуального анализа.
The religious and philosophical works of St. Nerses Shnorali (Nerses the Gracious) were on the agenda of many scientists research works. His spiritual creativity was translated into many languages (more than 36), occupying its honorable place in the world literary and cultural heritage.The purpose of the study is to carry out a research within the framework of St. Nerses Shnorali’s prayer “I Confess with Faith” and to reveal the principles of cultural transfer through the prism of comparison between the original and the translations (Russian, English, Italian). One cannot fail to observe that the prayer has a unique textual structure in which St. Nerses Shnorali illustrates twenty-four prayers for each hour of the day. The research comprehensively focuses on the structural and stylistic features of the prayer, the linguistic and extra-linguistic factors that influenced on the process of translation, as well as some strategic principles of transfer. A range of issues is outlined related to the translation peculiarities of the religiously marked units through the paradigm of the cultural transfer. The methodological basis of the article covers - the concept of cultural transfer, the method of reverse translation, comparative literature, textual and contextual analysis.
Perberdayaan Budidaya Jamur Tiram Sebagai Inovasi Kemandirian Ekonomi Di PT. Mitra Jamur Indonesia Jember
Authors: Sugianto Sugianto
Published: December 2023

Kehadiran PT. Mitra Jamur Indonesia lembaga yang bergerak di bidang budidaya jamur tiram di latar belakangi atas permintaan jamur yang semakin meningkat di pasar dan sebagai bentuk kepedulian dalam menciptakan ekonomi hijau dengan mengfungsikan sebidang tanah untuk bisa menciptakan penghasilan. Penelitian ini bertujuan untuk mengetahui bagaimana budidaya jamur tiram di PT. Mitra Jamur Indonesia sebagai inovasi kemadirian ekonomi meliputi Permberdayaan Budi Daya Jamur Tiram, Inovasi kemandirian ekonomi Produk Jamur Tiram. Penelitian ini berlokasi PT. Mitra Jamur Indonesia yang terletak di Jl. Merak No.64, Kedawung kidul, Gebang, Patrang, Jember, teknik penentuan sampel dengan purposive sampling, jenis data digunakan data kualitatif, pengumpulan data observasi, sumber data dari CEO dan Karyawan PT. Mitra Jamur Indonesia, teknik pengumpulan data yakni observasi, wawancara dan dokumentasi, jenis penelitiannya deskriptif. Hasil penelitian menemukan bahwa pemberdayaan budidaya jamur tiram sebagai inovasi kemandirian ekonomi menghasilkan beberapa penemuan, diantyaranya: pertama, praktik pembuatan jamur tiram mulai tahap penyiapan serbuk gergaji sampai proses inkubasi (pemeliharaan). Kedua, inovasi pembuatan produk melalui olahan jamur tiram yakni, kebab jamur, krispi jamur, nugget jamur, dan kaldu jamur. Hal yang paling menunjol dalam budidaya jamur tiram ialah adanya inovasi produk sebagai peningkat nilai jual persaingan pasar.
ASSESSMENT OF PHYSICAL DEVELOPMENT BY THE PROGRAM WHO ANTHROPLUS OF CHILDREN OF THE REPUBLIC OF TATARSTAN IN HEALTH INSTITUTIONS
Authors: Грицинская В.Л.
Published: December 2023

С целью изучения особенностей физического развития школьников, проживающих в Республике Татарстан, было обследовано 897 учащихся средних школ (415 мальчиков и 482 девочки) в возрасте от 7 до 17 лет. Во время пребывания школьников в летнем оздоровительном центре на юге страны проведена соматометрия (длина и масса тела), рассчитан массо-ростовой индекс (индекс массы тела, body mass index — BMI) и дана оценка физического развития учащихся с помощью антропометрического калькулятора WHO AnthroPlus. Выявлено, что от 26,2 до 37,5% учащихся имеют отклонения длины тела от средних возрастно-половых нормативов; преимущественно за счет роста выше среднего и в большей степени у мальчиков (р=0,015). Отклонения в нутритивном статусе имели от 27,1 до 43,7% обследованных школьников. Распространенность избыточной массы тела (5,5–13,7%) и ожирения (2,6–9,1%) у учащихся соответствуют общемировой тенденции. Однако следует обратить внимание на высокую распространенность дефицита массы тела, особенно ниже 5-го перцентиля (7,8–14,1%), что соответствует белково-энергетической недостаточности питания. Полученные результаты требуют более углубленного анализа питания детей в Республике Татарстан и разработки профилактических мероприятий.

In order to study the characteristics of the physical development of schoolchildren in the Republic of Tatarstan, 897 secondary school students (415 boys and 482 girls) aged from 7 to 17 years were examined. During the stay of schoolchildren in the summer health center, somatometry (body length and weight) was carried out, the mass-height index (BMI) was calculated and an assessment of the physical development of students was given using the anthropometric calculator WHO AnthroPlus. It was revealed that from 26.2 to 37.5% of students have deviations in body length from the average age-sex standards; mainly due to growth above average and to a greater extent in boys (p=0.015). Deviations in nutritional status were observed from 27.1 to 43.7% of the surveyed schoolchildren. The prevalence of overweight (5.5–13.7%) and obesity (2.6–9.1%) among students corresponds to the global trend. However, attention should be paid to the high prevalence of body weight deficit, especially below the 5th percentile (7.8–14.1%), which corresponds to protein-energy malnutrition. The results obtained require a more in-depth analysis of the nutrition of children in the Republic and the development of preventive measures.
ROLE OF LIRAGLUTIDE IN THE TREATMENT OF OBESITY IN CHILDREN
Authors: Евдокимова Н.В.
Published: December 2023

Цель исследования. Оценить эффективность препарата лираглутид на динамику массы тела и кардиометаболических параметров у детей с ожирением 12–17 лет. Материалы и методы. Обследовано 70 подростков с различной степенью ожирения. Исследовалось состояние углеводного и липидного обмена, функция печени, гормональный профиль, компонентный состав тела с помощью биоимпедансометрии. Дети были разделены на две группы: основную (50 человек) и сравнения (20 детей). Пациенты основной группы получали лечение препаратом лираглутид, а группы сравнения — придерживались рекомендаций, направленных на изменение образа жизни (рациональное питание и регулярные физические нагрузки). Результаты. Через 1,5 и 6 месяцев от начала медикаментозного лечения в основной группе SDS индекс массы тела (ИМТ) снизился на 0,25 и 0,4 соответственно, в группе сравнения — на 0,25 только через 5 недель, а через 6 месяцев показатель вновь вернулся к исходному значению. Похудение детей, получавших лираглутид, сопровождалось снижением жировой массы и ее доли. Дети, которые не получали препарат, похудели за счет снижения скелетно-мышечной массы и жидкости в организме. У 80% пациентов при использовании фармакотерапии отмечалось улучшение кардиометаболических параметров. Заключение. Высокая эффективность препарата лираглутид связана с механизмом его действия, т.е. нормализацией системы регуляции аппетита. Это способствовало не только снижению массы тела, но и удержанию достигнутого результата.

The aim of the study. To evaluate the effectiveness of the drug liraglutide on the dynamics of body weight and cardiometabolic parameters in obese children aged 12–17 years. Materials and methods. 70 adolescents with varying degrees of obesity were examined. The state of carbohydrate and lipid metabolism, liver function, hormonal profile, and body component composition were studied using bioimpedance. The children were divided into two groups: the main group (50 people) and the comparison group (20 children). The patients of the main group received treatment with liraglutide, the comparison groups followed the recommendations aimed at lifestyle changes (rational nutrition and regular physical activity). Results. After 1.5 and 6 months from the start of drug treatment in the main SDS group, the BMI decreased by 0.25 and 0.4, in the comparison group — by 0.25 only after 5 weeks, and after 6 months the indicator returned to its original value. The weight loss of children receiving liraglutide was accompanied by a decrease in fat mass and its proportion. Children who did not receive the drug lost weight due to a decrease in musculoskeletal mass and fluid in the body. In 80% of patients, when using pharmacotherapy, there was an improvement in cardiometabolic parameters. Conclusion. The high efficacy of the drug liraglutide is associated with the mechanism of its action, i.e. normalization of the appetite regulation system. This contributed not only to a decrease in body weight, but also to the retention of the achieved result.
ESTILOS DE SOCIALIZACIÓN PARENTAL Y ACOSO ESCOLAR EN ESTUDIANTES DE EDUCACIÓN SECUNDARIA DE UN COLEGIO PÚBLICO DE VILLA EL SALVADOR
Authors: Sánchez C. Emily
Published: December 2023

Se determinó la relación entre el estilo de socialización parental y el acoso escolar en una muestra de estudiantes de secundaria de una escuela pública de Villa El Salvador. La muestra estuvo compuesta por 337 estudiantes de secundaria de 2do a 5to grado, con edades entre 12 y 17 años, independientemente del género. Se utilizó la Escala de Socialización de Padres y la Escala de Autoevaluación de Bullying de Cisneros. Los resultados mostraron que los patrones de socialización promediaron entre todos los padres; madres y padres entre los estudiantes. Por otro lado, el 57,9% se encuentra en un nivel medio de acoso, seguido del 18,7% en un nivel inferior y el 23,4% en un nivel alto y muy alto. También hubo diferencias significativas en los estilos de socialización parental para madres y padres, así como en variables de acoso basadas en la edad y variables de rendimiento escolar. Finalmente, existe una correlación negativa, baja y estadísticamente significativa entre el puntaje total de acoso y el estilo emocional, por otro lado, existe una correlación positiva, baja y estadísticamente significativa entre el puntaje total de acoso y el estilo indiferente, coerción física y privación.
INDICE COMPLETO 2021 Vol6N2
Authors: Investigacion Investigacion
Published: December 2023

.
INDICE COMPLETO 2022 Vol7N2
Authors: Investigacion Investigacion
Published: December 2023

.
DEPRESIÓN, FUSIÓN COGNITIVA Y SU RELACIÓN CON LA DESREGULACIÓN EMOCIONAL EN UNIVERSITARIOS DE LIMA METROPOLITANA
Authors: Blancas G. Percy
Published: December 2023

El objetivo determinar la relación entre depresión y fusión cognitiva con la desregulación emocional (DRE) en universitarios de Lima Metropolitana. La muestra estuvo compuesta por 421 universitarios, de los cuales 136 fueron varones y 285 mujeres. Se emplearon como instrumentos: Inventario de Depresión de Beck BDI – II, Cuestionario de Fusión cognitiva (CFQ-VP) y Escala de dificultades en la regulación emocional (DERS). Los resultados indican que las variables depresión y fusión cognitiva explican en 0.456 % la desregulación emocional, cabe destacar, el modelo de importancia práctica de tamaño grande (f2 > 35).
INTELIGENCIA EMOCIONAL Y AUTOESTIMA EN ESTUDIANTES DE SECUNDARIA DE UNA INSTITUCIÓN EDUCATIVA DE VILLA EL SALVADOR, 2022
Authors: López V. Israel
Published: December 2023

Relacionaron inteligencia emocional y autoestima en educandos de nivel secundario de una institución de Villa El Salvador. La muestra estuvo compuesta por 250 adolescentes de 13 a 17 años y se emplearon los instrumentos: el Inventario de Inteligencia Emocional Baron ICE: NA y el Test de Autoestima para Escolares. Los resultados indican que, el 36.61% de estudiantes reportan un nivel alto la inteligencia emocional, el 32.32% en nivel bajo y en nivel promedio el 31.07%. En cuanto a la autoestima, el 37.14% de estudiantes se muestra en nivel alto, el 32.14% en nivel promedio y en nivel bajo con 30.71%. Además, la inteligencia emocional y la autoestima se correlacional de forma directa y significativamente; es decir, que a mayor sea la inteligencia emocional menor será la autoestima en los estudiantes.
PROPIEDADES PSICOMÉTRICAS DE LA ESCALA DE BIENESTAR PSICOLÓGICO DE RIFF EN ADOLESCENTES DE LIMA NORTE
Authors: Chauca C. Max , Briones F. Rodrigo
Published: December 2023

El bienestar psicológico se ha relacionado fundamentalmente a la felicidad y a la satisfacción con el desarrollo personal, suele influir en el accionar de cada individuo, especialmente en los adolescentes, debido a que una percepción positiva del mismo, brinda la posibilidad de mantener una buena salud mental, en ese sentido requiere de instrumentos que evidencien validez y confiabilidad y adaptado a población de adolescentes. El presente estudio tuvo como objetivo analizar las propiedades psicométricas de la Escala de Bienestar Psicológico de Ryff en adolescentes. Se aplicó la escala adaptada por Pérez de 39 ítems a una muestra de 300 estudiantes adolescentes de entre 12 a 17 años, residentes en Lima norte. Para estudiar la escala y determinar la validez del modelo propuesto se utilizó el análisis factorial confirmatorio (AFC). Los resultados del AFC confirman un nivel de ajuste insatisfactorio respecto al modelo original (X2=1508.71; gl=687; p= 0.00; CFI=0.81; TLI=0.80; RMSEA=0.07 y SRMR=0.07), mientras que un segundo modelo de tres dimensiones obtenido del gráfico de sedimentación también obtuvo valores bajos como el original e insatisfactorios (X2=1185.85; gl=591; p=0.00; CFI=0.79; TLI=0.78; RMSEA=0.06 y SRMR=0.07), sin embargo un tercer modelo propuesto de 2 dimensiones con ítems eliminados, obtuvo un nivel de ajuste satisfactorio (X2=280.70; gl=169; p=0.00; CFI=0.92; TLI=0.91; RMSEA=0.05 y SRMR=0.05). La consistencia interna de la escala propuesta, medida por el Alfa de Cronbach fue de 0.816, siendo un valor robusto e indicando una alta confiabilidad. Además, la Prueba T Student obtuvo valores en el modelo propuesto de p iguales a 0.512, 0.316 y 0.820, indicando que no hay diferencias en el bienestar psicológico entre hombres y mujeres.
Nonalcoholic Fatty Liver Disease, Procalcitonin, and Gut Microbiota: Players in the Same Team
Authors: Georgescu Doina , Lascu Ana , Ionita Ioana , Ancusa Oana-Elena , Ionita Mihai , Rosca Ciprian , Calamar-Popovici Despina , Lighezan Daniel
Published: December 2023

The study aimed to assess the link between procalcitonin (PCT) and gut dysbiosis in patients with nonalcoholic fatty liver disease (NAFLD). A total of 125 research participants, 100 patients with NAFLD (59% women and 41% men) age between 43 and 84 years and 25 healthy controls, joined this observational study. Patients were consecutively enrolled into two groups: 50 with gut dysbiosis and 50 without gut dysbiosis, after several conditions have been ruled out. Patients from dysbiotic group displayed significantly lesser use of biguanides and statins and elevation of fatty liver index (FLI), PCT, C-reactive protein (CRP), and alanine aminotransferase (ALT). Their gut microbiome was characterized by Bacteroides and Prevotella sp. dominant enterotype (74%) and by Ruminococcus sp. in only 26% of cases. The decrease of H index of biodiversity was observed in 64% of patients as well as of Firmicutes/Bacteroidetes (F/B) ratio and Akkermansia muciniphila in 60%. The increase of lipopolysaccharide positive bacteria was noted in 62% of patients. PCT strongly correlated with the level of CRP and ALT as well as to stool’s H index of biodiversity and F/B ratio. Dysbiotic patients with NAFLD exhibited significant elevation of PCT that correlated well with the H index of stool’s microbiota biodiversity, F/B ratio, CRP level, and severity of cytolytic syndrome.
The Environmental Impact on Advanced Midwives from Underutilization in Tertiary Hospital
Authors: Rhona Luphai Mbulaheni
Published: December 2023

Advanced midwifery practice is an autonomous status that is developed during midwifery training and practices. Advanced midwives in their practice are expected to take full responsibility when it comes to patients under their care. However, in tertiary hospitals, all the care given to maternity patients yields grey area which needs responsibility sharing between the midwives and other multidisciplinary team members like obstetric doctors and paediatric doctors. The tertiary environment is over-clouded by medical-dependent practices which is widened by the communication gap between the multidisciplinary teams. Lack of professional communication in tertiary hospitals’ work environment when it comes to sharing of accountability pushes the midwives to their cocoon shells which make them lose their patient advocacy role, knowledge, and skills. Based on the environmental expectations, set ups and practices, patients end up receiving compromised maternity care which open doors to major malpractices and complications like unnecessary loss of lives and litigations. In the presence of malpractices, there is always a tendency of the multidisciplinary team members blaming each other and mostly the blamed professionals are the midwives which strains the environmental professional relationships.
Perspectives of Organic Dyes Cosensitization and Its Utilization in TiO2 Nanoclusters for Photocatalysis Applications
Authors: Barraza-Jiménez Diana , Manuel Lerma Mancinas Derian , Iván Flores-Hidalgo Hugo , Armando Olvera Corral Raúl , Iliana Torres-Herrera Sandra , Alberto Flores-Hidalgo Manuel
Published: December 2023

Cosensitization has emerged as a method to improve performance of dye sensitized solar cells (DSSCs) and photocatalysis. In this work, it is proposed to use organic dyes as cosensitizers due to their friendliness with the environment and to the benefits of having two or more different dyes with complementary optical absorption characteristics. Several organic dyes are analyzed as cosensitizers to identify which dye combinations may be good choices to approach a panchromatic absorption spectrum emulating the solar emission spectrum. In addition to the analysis on the prospective sensitizers, it is presented results of titanium dioxide (TiO2) nanoclusters cosensitized with two anthocyanidins using density functional theory (DFT) and time-dependent DFT (TD-DFT). The nanocluster size proved to be definitive in the interactions with two molecule dyes. The selected (TiO2)4–5 nanoclusters cosensitized with two anthocyanidins produce data for a prospective analysis to suggest which dyes are good options for DSSCs and photocatalysis based on dye co-sensitization applications. At the end, one can look at this work as a perspective of which organic dyes may work well as cosensitizers and a contrast to original data from our experimentation with a couple of TiO2 nanoclusters cosensitized with two different anthocyanidins.
Refusal and politeness strategies favoured among Iraqi and Malaysian learners in marriage proposals
Authors: Tabarek Ali Qassim , Nawal Fadhel Abbas , Hooi Chee Mei
Published: December 2023

The study targets exploring the similarities and differences between Iraqi and Malaysian learners of English in refusing marriage proposals. Also, it examines the favored politeness strategies that learners use to protect their interlocutors’ face, heeding both their social distance and status. Data were gathered by a Discourse Completion Task (DCT) which contained six marriage situations. Responses were analyzed based on Beebe et al.’s (1990) refusal taxonomy and Scollon et al.’s (2012) politeness system. The findings indicated that both the Iraqi and Malaysian learners preferred the indirect refusal strategies in marriage proposals, as well as the hierarchical politeness in the form of independence strategies regardless of the social status and distance between interlocutors. However, they differed in the sort of indirect strategies most frequently utilized. The Iraqi learners favored reason, regret, and non-performative statements, whilst the Malaysian learners preferred regret, non-performative statements, and reason.
First language and second language English editorialists’ use of interactional metadiscourse
Authors: Alghazo Sharif , Al-Anbar Khulood , Altakhaineh Abdel Rahman , Jarrah Marwan
Published: December 2023

This study explores the use of interactional1 metadiscourse by first language (L1) and second language (L2) English editorialists. The study uses Hyland’s (2019) model of metadiscourse to analyse 80 editorials published between 2020 and 2021 in The Guardian and The Jordan Times newspapers (40 from each newspaper). A mixed-method approach  – adopting quantitative and qualitative measures – was used to analyse the data. The frequency of interactional metadiscourse resources was statistically examined to find similarities and differences (if any) between the two corpora. The analysis revealed a statistically significant difference in the use of interactional metadiscourse resources in the editorials of the two newspapers. For instance, L2 editorialists used fewer hedges in their editorials and more boosters than L1 editorialists. In addition, engagement markers were used the most by L1 editorialists. The study provides some implications for editorialists who write in English and recommendations for future research.
A pragmatic approach to the rhetorical analysis and the metadiscourse markers of research article abstracts in the field of applied linguistics
Authors: Hasan Eatidal , Ergaya Alsout
Published: December 2023

Using Hyland’s (2000) model as a research tool and drawing on Hyland’s (2005a) model of metadiscourse, this article presents a pragmatic two-level rhetorical analysis of the constituent moves within research article abstracts. It specifically zeroes in on the identification and mapping of the most frequently used metadiscourse markers signifying these moves. The findings highlight that Libyan authors employ interactive markers more often than interactional ones. Both quantitative and qualitative analysis of metadiscourse indicate that transitions, endophoric markers, and frame markers emerge as the dominant interactive categories. In contrast, interactional metadiscourse is predominantly represented by attitude markers, hedges, and boosters. Based on the findings, Move 1 features the highest frequency of metadiscourse markers, followed by Move 2. Notably, transitions stand out as the most prevalent category across all moves. This study carries pedagogical implications for academic writing practices among Libyan academic writers and students alike. Moreover, it enhances the existing body of research on the genre of research articles.