bluuebunny/crossref_metadata_2025 huggingface dataset:
Parametrizing linear generalized Langevin dynamics from explicit molecular dynamics simulations
Authors: Gottwald Fabian , Karsten Sven , Ivanov Sergei D. , Kühn Oliver
Published: June 2015

Fundamental understanding of complex dynamics in many-particle systems on the atomistic level is of utmost importance. Often the systems of interest are of macroscopic size but can be partitioned into a few important degrees of freedom which are treated most accurately and others which constitute a thermal bath. Particular attention in this respect attracts the linear generalized Langevin equation, which can be rigorously derived by means of a linear projection technique. Within this framework, a complicated interaction with the bath can be reduced to a single memory kernel. This memory kernel in turn is parametrized for a particular system studied, usually by means of time-domain methods based on explicit molecular dynamics data. Here, we discuss that this task is more naturally achieved in frequency domain and develop a Fourier-based parametrization method that outperforms its time-domain analogues. Very surprisingly, the widely used rigid bond method turns out to be inappropriate in general. Importantly, we show that the rigid bond approach leads to a systematic overestimation of relaxation times, unless the system under study consists of a harmonic bath bi-linearly coupled to the relevant degrees of freedom.
Thermo-acoustic engineering of silicon microresonators via evanescent waves
Authors: Tabrizian R. , Ayazi F.
Published: June 2015

A temperature-compensated silicon micromechanical resonator with a quadratic temperature characteristic is realized by acoustic engineering. Energy-trapped resonance modes are synthesized by acoustic coupling of propagating and evanescent extensional waves in waveguides with rectangular cross section. Highly different temperature sensitivity of propagating and evanescent waves is used to engineer the linear temperature coefficient of frequency. The resulted quadratic temperature characteristic has a well-defined turn-over temperature that can be tailored by relative energy distribution between propagating and evanescent acoustic fields. A 76 MHz prototype is implemented in single crystal silicon. Two high quality factor and closely spaced resonance modes, created from efficient energy trapping of extensional waves, are excited through thin aluminum nitride film. Having different evanescent wave constituents and energy distribution across the device, these modes show different turn over points of 67 °C and 87 °C for their quadratic temperature characteristic.
Electrical conductivity in Langmuir-Blodgett films of n-alkyl cyanobiphenyls using current sensing atomic force microscope
Authors: Gayathri H. N. , Suresh K. A.
Published: June 2015

We report our studies on the nanoscale electrical conductivity in monolayers of n-alkyl cyanobiphenyl materials deposited on solid surface. Initially, the 8CB, 9CB, and 10CB monolayer films were prepared by the Langmuir technique at air-water interface and characterized by surface manometry and Brewster angle microscopy. The monolayer films were transferred on to solid substrates by the Langmuir-Blodgett (L-B) technique. The 8CB, 9CB, and 10CB monolayer L-B films were deposited on freshly cleaved mica and studied by atomic force microscope (AFM), thereby measuring the film thickness as ∼1.5 nm. The electrical conductivity measurements were carried out on 9CB and 10CB monolayer L-B films deposited onto highly ordered pyrolytic graphite using current sensing AFM. The nanoscale current-voltage (I-V) measurements show a non-linear variation. The nature of the curve indicates electron tunneling to be the mechanism for electrical conduction. Furthermore, analysis of the I-V curve reveals a transition in the electron conduction mechanism from direct tunneling to injection tunneling. From the transition voltage, we have estimated the values of barrier height for 9CB and 10CB to be 0.71 eV and 0.37 eV, respectively. For both 9CB and 10CB, the effective mass of electron was calculated to be 0.021 me and 0.065 me, respectively. These parameters are important in the design of molecular electronic devices.
Electrical passivation of nonselective bio molecules in carbon nanotubes: Effect of pulse train in serum
Authors: Kim Seok Hyang , Woo Jun-Myung , Choi Seongwook , Park Young June
Published: June 2015

We present an experimental and simulation study about a desorption of albumin, a representative nonselective molecules in serum, on carbon nanotube (CNT) surface as an electrical bio sensing channel under the pulse train condition. The motivation of the study on binding kinetics between CNT surface and albumin is to suppress the adsorption of nonselective proteins in blood such as albumin, thereby enhancing the selectivity of the electrical biosensor. To theoretically model the behavior of molecules and ions under the step pulse bias, the physics on the reaction rate, mass transport, and the resulting surface pH-value are considered using the Poisson and drift-diffusion equations. For the simulation model, the phosphate buffered saline is considered as the electrolyte solution and albumin is considered as a representative charged molecule for nonspecific binding in serum. Both the transient simulation and experimental result indicate that the suppression of the nonspecific binding under the pulse train is due to the unsymmetrical field force experienced by the protein during the pulse transitions (high to low and low to high) and the non-symmetry is caused by the different transient times between the electric field and the charge/discharge of the protein according to the surface pH modulation in serum. The experimental and simulation results clearly indicate that the pulse bias suppresses the nonselective bio molecules adsorption at the CNT surface so that the selectivity of the electrical biosensor for detecting the target molecules can be enhanced.
Low-noise cold-field emission current obtained between two opposed carbon cone nanotips during in situ transmission electron microscope biasing
Authors: de Knoop L. , Gatel C. , Houdellier F. , Monthioux M. , Masseboeuf A. , Snoeck E. , Hÿtch M. J.
Published: June 2015

A dedicated transmission electron microscope sample holder has been used to study in situ the cold-field emission process of carbon cone nanotips (CCnTs). We show that when using a CCnT instead of a Au plate-anode, the standard deviation of the emission current noise can be decreased from the 10 nA range to the 1 nA range under vacuum conditions of 10−5 Pa. This shows the strong influence of the anode on the cold-field emission current noise.
Is health workforce planning recognising the dynamic interplay between health literacy at an individual, organisation and system level?
Authors: Naccarella Lucio , Wraight Brenda , Gorman Des
Published: June 2015

The growing demands on the health system to adapt to constant change has led to investment in health workforce planning agencies and approaches. Health workforce planning approaches focusing on identifying, predicting and modelling workforce supply and demand are criticised as being simplistic and not contributing to system-level resiliency. Alternative evidence- and needs-based health workforce planning approaches are being suggested. However, to contribute to system-level resiliency, workforce planning approaches need to also adopt system-based approaches. The increased complexity and fragmentation of the healthcare system, especially for patients with complex and chronic conditions, has also led to a focus on health literacy not simply as an individual trait, but also as a dynamic product of the interaction between individual (patients, workforce)-, organisational- and system-level health literacy. Although it is absolutely essential that patients have a level of health literacy that enables them to navigate and make decisions, so too the health workforce, organisations and indeed the system also needs to be health literate. Herein we explore whether health workforce planning is recognising the dynamic interplay between health literacy at an individual, organisation and system level, and the potential for strengthening resiliency across all those levels.
Knowledge of the reproductive ecology of the invasive Salix cinerea, in its invaded range, assists in more targeted management strategies
Authors: Hopley Tara , Young Andrew G.
Published: June 2015

Management for invasive species is expensive, costing millions of dollars every year and is sometimes unsuccessful. Current control efforts for the highly invasive willow species, Salix cinerea, are extensive, costly, and not always effective because of rapid post-removal reinfestation. An improved knowledge of the reproductive ecology of this species will help design control strategies that minimise future expansion and make current control efforts more effective. To explicitly examine the reproductive ecology of this species in its invaded range in south-eastern Australia, field observations of population structure and sex ratios, pollination experiments and germination trials were undertaken across the Ovens catchment in Victoria. Pollination-exclusion experiments strongly suggest that Salix cinerea in Australia employs two pollen-dispersal mechanisms, with insects being the dominant vector and wind playing a small but significant role (ambophilous). Seed had high initial germination rates, above 95%, but seed is very short-lived with rapid linear decline in germinability until 8 weeks, after which there was no germination at all. An improved understanding of the limited seed bank of this species and the potential it has for long distance pollination has highlighted that preventing reinfestation after control efforts should be focussed on limiting seed production and dispersal. A greater understanding of a species reproductive ecology, particularly of weed species, in their new environment can assist land managers to more effectively target their efforts for long-term eradication strategies.
Ovarian suppression in a marsupial following single treatment with a gonadotrophin-releasing hormone agonist in microspheres
Authors: Witt Ryan Robert , Forbes Ian Ross , McBain John , Rodger John Cameron
Published: June 2015

The effect of treatment with Lucrin Depot (1 month), a microsphere gonadotrophin-releasing hormone agonist preparation, was investigated in the fat-tailed dunnart (Sminthopsis crassicaudata) as a potential strategy to synchronise cycling. The status of the ovaries (ovarian size, number and size of Graafian follicles and corpora lutea) and reproductive tract (weight, vascularity and muscularity) in twelve untreated females were assessed to establish the activity parameters for randomly selected cycling animals. Thirty-six females were treated with 1 mg kg–1 (n = 12), 10 mg kg–1 (n = 12) or 20 mg kg–1 (n = 12) Lucrin Depot. At 4, 6 and 8 weeks the reproductive tracts were assessed using the criteria developed in the untreated females. All of the females treated with 10 mg kg–1 showed suppression at 4 weeks and 25% showed return of reproductive activity at 8 weeks. A dose of 1 mg kg–1 did not appear to suppress reproductive activity and 20 mg kg–1 gave equivocal results, with evidence of both suppression and activity. The results indicate that Lucrin Depot appears to be a promising agent to regulate and potentially synchronise breeding activity in the fat-tailed dunnart.
Iris atrofusca genetic and phenotypic variation, the role of habitat-specific selection in this variation structuring, and conservation implications using quasi in situ guidelines
Authors: Volis Sergei , Zhang Yong-Hong , Dorman Michael , Blecher Michael
Published: June 2015

Knowing the extent and structure of genetic variation in an endangered species is essential for establishing efficient conservation practices. However, the proper use of this information requires understanding the role of habitat-specific selection in genetic structuring. We present a study of population differentiation in an endangered species that utilizes guidelines of recently a proposedquasi in situconservation approach, i.e. taking into account the scale and spatial pattern of local adaptation since if local adaptation is important, the introduced genotypes must be matched to the local biotic/abiotic conditions. Following this approach, we examined the extent and structure of genetic (AFLP) and phenotypic variation and tested for adaptive significance of this variation in critically endangeredIris atrofuscagrowing in Israel and Jordan. From these results we propose a sampling design that would (i) preserve species adaptive potential and (ii) insure environmental match of the plant material for relocation, reintroduction or enhancement.
False hashish without cannabis resin
Authors: Hanuš Lumír O. , De La Vega Dafna , Roman Michael , Tomíček Pavel
Published: June 2015

A substance that looked like hashish, seized in Israel and the Czech Republic was analyzed with a GC/MS for the identification of the main cannabinoids expected in cannabis (Cannabis sativa). No compounds typical of cannabis were identified in either of the two sets of samples, but compounds typical of coniferous plants, most probably from pine, and henna (Lawsonia inermis), were identified (various alcohols and organic acids).
A marginal band of microtubules transports and organizes mitochondria in retinal bipolar synaptic terminals
Authors: Graffe Malkolm , Zenisek David , Taraska Justin W.
Published: June 2015

A set of bipolar cells in the retina of goldfish contains giant synaptic terminals that can be over 10 µm in diameter. Hundreds of thousands of synaptic vesicles fill these terminals and engage in continuous rounds of exocytosis. How the cytoskeleton and other organelles in these neurons are organized to control synaptic activity is unknown. Here, we used 3-D fluorescence and 3-D electron microscopy to visualize the complex subcellular architecture of these terminals. We discovered a thick band of microtubules that emerged from the axon to loop around the terminal periphery throughout the presynaptic space. This previously unknown microtubule structure associated with a substantial population of mitochondria in the synaptic terminal. Drugs that inhibit microtubule-based kinesin motors led to accumulation of mitochondria in the axon. We conclude that this prominent microtubule band is crucial to the transport and localization of mitochondria into the presynaptic space to provide the sustained energy necessary for continuous transmitter release in these giant synaptic terminals.
Case 1
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Access section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 3
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Access section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 6
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Access section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 10
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 13
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 14
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 15
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 16
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 18
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 20
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Biopsy section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 24
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Ablation section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 25
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Ablation section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 29
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 30
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 31
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 32
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 33
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 34
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 36
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 37
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 41
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 43
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 44
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 45
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Embolization section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 47
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Genitourinary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 49
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Genitourinary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 51
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Genitourinary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 52
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Gastrointestinal/Biliary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 55
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Gastrointestinal/Biliary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 56
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Gastrointestinal/Biliary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 57
Authors: Covey Anne M. , Pua Bradley B. , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Gastrointestinal/Biliary Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 66
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 67
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 70
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 73
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 74
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 75
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Venous Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 76
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 81
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 82
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 83
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 86
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 87
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 90
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 92
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Arterial Intervention section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 93
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Drainage section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 95
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Drainage section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 96
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Drainage section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 97
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Drainage section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 101
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Drainage section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 102
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Spine Augmentation section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
Case 103
Authors: Covey Anne M. , Pua Bradley B , Aguado Allison , Madoff David C.
Published: June 2015

This is a case from the Spine Augmentation section of Interventional Radiology Cases. The specific content of each case and its diagnosis are necessarily hidden from this abstract. Each case contains case history, followed immediately by the diagnosis, which is supported with findings, differential diagnosis, teaching points, management, and further reading suggestions.
The sepsis resuscitation bundle
Authors: Khalek Adham , Keep Jeff , Rivers Emmanuel
Published: June 2015

This chapter provides an overview of the recognition and treatment of Sepsis in the acute phase. It discusses the biochemical and physiological parameters which assist in the recognition and diagnosis of sepsis.

This chapter examines the evidence for the early use of antibiotics and discusses the ED infrastructure required to ensure this is possible. Fungal infections are also discussed and risk factors for such infections are highlighted.

The evidence behind the concept of early goal-directed therapy and care bundles is discussed in relation to the early treatment of sepsis. The use of noradrenaline for patients with hypotension not responsive to fluids is described as advised by the College of Emergency Medicine. Interventions are discussed in relation to reduction in mortality for this group of patients. Ongoing trials in the area of sepsis management are recognized.
Traumatic occult pneumothorax
Authors: Hudson Anthony , Porter Keith
Published: June 2015

The chapter provides an overview of the challenges facing the emergency physician dealing with a poly-trauma patient and the discovery of an occult pnuemothorax.It examines the role of immediate FAST scanning in the emergency department and the vogue for the trauma CT pan scan.

It examines the evidence base for key clinical questions including the role of extended FAST scan to examine the chest cavity for pneumothoraces, and outlines the key radiological signs needed to be elicited on ultrasound. It then continues to explore the place for conservative versus interventional chest-drain management of those patients with asymptomatic pneumothoraces and the subsequent follow-up management required.
Facial burns and inhalation injury
Authors: Bootland Duncan , Dheansa Baljit
Published: June 2015

The chapter provides an overview of the challenges facing the emergency physician dealing with a patient who is involved in a fire and may have facial burns and a potential airway problem. The chapter highlights the potential pitfalls in diagnosis of a potential airway burn.

It examines the evidence base for three clinical questions: who in a suspected inhalational injury requires intubation;which patients should a cyanide antidote be administered to; and which antidote should be used. The third clinical question discusses which patients with suspected carbon-monoxide poisoning require hyperbaric oxygen therapy.Fluid recommendations and inhalational therapies are discussed.
Paediatric head injury
Authors: Cantle Fleur , Sutherland Emer
Published: June 2015

This chapter provides an overview of the challenges facing the emergency physician dealing with a child with a deteriorating head injury. It describes the differences in incidence and injury patterns between the adult and paediatric population and the key decision-making tools and initial treatment options available in the emergency department.

It examines the evidence base for three key clinical questions: which children require immediate CT neuroimaging; the role of hypertonic saline in reducing the intracranial pressures of a traumatic brain injury; and finally the role of therapeutic cooling in outcomes in brain injury. Consideration is given to the issue of concurrent neck injuries and the chapter looks forward to future biomarkers that may stratify paediatric head injuries further.
Vaginal bleeding in early pregnancy
Authors: Das Rita , Stevens Lindsey
Published: June 2015

This chapter provides an overview of the challenges facing the emergency physician dealing with a patient who is bleeding in the early stages of pregnancy. It describes the importance of a detailed assessment in such patients and particularly highlights the importance of considering a diagnosis of ectopic pregnancy in all women of child-bearing age. The relatively rare diagnosis of heterotopic pregnancy is discussed.

It examines the evidence base for three key clinical questions: what the role may be for the emergency physician to perform in early pregnancy scanning in the emergency department; which patients with ectopic pregnancies can be treated conservatively; and what is the role of the emergency department in using anti-D in Rhesus-negative women in ectopic pregnancies.
Corneal injury
Authors: Gidwani Shweta , Beckett Mike
Published: June 2015

This chapter provides an overview of the challenges facing the emergency physician dealing with a patient with a potential penetrating foreign body in the eye. It discusses the examination of such patients including theSiedel test

It examines the evidence base for three key clinical questions:the best imaging modality in the presence of a suspected intraocular foreign body;the use of routine antibioticsin the acute management of corneal abrasions; and the most appropriate analgesia to administer. The use of mydiatics and eye patches is also discussed and special consideration is given to those patients who wear contact lenses.
Complex wrist fractures
Authors: Coughlan Evan , Thenabadu Sam , Ryan John
Published: June 2015

This chapter provides a discussion of the challenges facing the emergency physician dealing with the complex and unstable wrist fracture in the emergency department. It describes an overview of the range of potential fracture presentations and the radiographical signs that will be seen. It describes the options of anaesthesia and manipulation and the potential for nerve injuries.

It examines the evidence base for three key clinical questions: the use of early manipulation to minimize nerve damage even in the cohort that will require definitive fixation; a comparison with the different anaesthietic techniques (haematoma block versus Bier’s block); and an examination of the potential use of ultrasound to assess fractures and their position post reduction.
Fever in the ED
Authors: Ejimofo Chidi , Thenabadu Sam , Christian Beth
Published: June 2015

This chapter provides a discussion of the challenges facing the emergency physician dealing with a patient presenting with a fever after recent foreign travel. It describes an overview of the range of potential differentials and the history, examination, and investigation profiles required. It focuses on the investigation of malaria via rapid diagnostic tests and the treatment options for falciparum malariae.

It examines the evidence base for three key clinical questions: the use of rapid diagnostic tests; the clinical importance of neutropenia in light of infection and potential illness; and the criteria for consideration of outpatient falciparum. The chapter also explores the role of HIV screening and testing in the emergency department setting.
Tricyclic antidepressant overdose
Authors: Rao Shwetha , Townsend Emma , Dargan Paul
Published: June 2015

This chapter provides a discussion of the challenges facing the emergency physician when dealing with a patient who is acutely unwell following an overdose of tricyclic antidepressants. It discusses the toxic effects of tricyclic antidepressants

It examines the evidence base for three key clinical questions: the appropriateness of gastric decontamination; investigations as markers of toxicity of overdose; and the use of sodium bicarbonate. The importance of ECG changes is highlighted and additional adjuvant treatments which might be used are introduced.
Febrile seizures
Authors: Beynon Rhys , Maconochie Ian
Published: June 2015

This chapter provides a discussion of the challenges facing the emergency physician dealing with a child who has had a seizure within an episode of febrile illness. It provides an overview of febrile convulsions and a discussion of the possible causes for seizures in children together with a system of classification of seizures.

It examines the evidence base for three key clinical questions:the pharmacological control of seizures;the use of neuroimaging; and the necessity for lumbar puncture. The duration of observation following seizure and discharge advice are discussed.
Safeguarding: recognizing the abused child and acting on the evidence base
Authors: Spedding Jessica , Walsh Simon , Riddell Anna
Published: June 2015

This chapter provides a discussion of the challenges facing the emergency physician dealing with an injured child in whom non-accidental injury is suspected. The categories of abuse are presented and the importance of a full assessment and the utilization of safeguarding checklists discussed.

It examines the evidence base for three key clinical questions:the assessment of bruises; the assessment of bony injuries;and the circumstances in which information can be shared with other agencies.
Femoral nerve block for fractured neck of femur
Authors: Sadek Samy , Thenabadu Sam , Stone Michael
Published: June 2015

This chapter provides a discussion of the challenges facing the emergency physician dealing with an elderly patient presenting with a neck of femur fracture in ongoing pain. It describes an overview of the range of both pharmacological analgesics as well as regional anaesthesia options available, as well as a consideration of the use of ultrasound-guided or blind application of blocks.

It examines the evidence base for three key clinical questions: examining the role for intravenous paracetamol in the initial treatment of neck of femur fractures; a review of femoral blocks as an effective analgesia for both intra and extra capsular fractures; and a comparison of blind fascia illiaca blocks compared with femoral blocks.