bluuebunny/crossref_metadata_2025 huggingface dataset:
Intimate partner femicide: Risk factors and the heterogeneity of male-perpetrated IPF in Queensland
Authors:   , McLachlan Freya
Published: February 2023

Intimate partner femicide (IPF), the murder of women by current or previous partners, is a global epidemic. This thesis examined 100 cases of male perpetrated IPF in Queensland to explore the characteristics of IPF and use them to create a typology of perpetration. Using coronial data, this mixed methods research unpacked the frequency of risk factors and highlighted themes of violence within the narratives of IPF cases. By exploring the commonalities and differences in IPF perpetration, this research provides weight to existing research and offers unique findings that have implications on future research, policy, and practice.
TECNOLOGIAS EDUCACIONAIS PARA CUIDADORES FAMILIARES DE CRIANÇAS E ADOLESCENTES COM DEFICIÊNCIA MOTORA: REVISÃO INTEGRATIVA
Authors: Nascimento Tatiane Oliveira , De Souza Yuri Leandro do Carmo , Do Nascimento Rodolfo Gomes , Cunha Katiane da Costa , Silva Simone Souza da Costa
Published: February 2023

Objetivo: identificar e descrever as tecnologias educacionais direcionadas a cuidadores familiares de crianças e adolescentes com deficiência motora apresentadas pela literatura especializada. Método: trata-se de um estudo bibliográfico, do tipo revisão integrativa de literatura, realizada nas bases de dados BVS, LILACS, MEDLINE, Pubmed e Scielo, entre 2011 e 2021, em português, inglês e espanhol, utilizando os descritores: caregivers, educational technology, disability, physical disability, handicap e health education. Analisaram-se os artigos pela leitura reflexiva e criteriosa acerca das principais informações e elementos que compõem a temática nos estudos. Resultados: foram incluídos 25 estudos. As tecnologias educacionais identificadas foram: cartilha/guia/manual (32%), grupo (28%), palestra (25%), treinamento (16%) e ferramenta digital (4%). Conclusão: as tecnologias educacionais desempenham papel importante na dinâmica do cuidar, pois as ações educativas em saúde são capazes de modificar atitudes e proporcionar segurança e qualidade de vida. Descritores: Tecnologia educacional; Cuidadores familiares; Deficiência motora; Crianças e adolescentes; Educação em saúde
El dadaísmo de Eisenstein en El diario de Glumov
Authors: Lope-Salvador Víctor
Published: February 2023

Eisenstein realizó en 1923 un cortometraje que formó parte de un espectáculo teatral titulado El diario de Glumov. Este film es su primera obra cinematográfica y está considerado como un experimento dadaísta. La obra teatral El diario de un pillastre que Ostrovsky estrenó en 1868 en Moscú es la base del espectáculo ideado por el cineasta para el Proletkult. En este artículo analizamos una selección de recursos y de motivos empleados en esta cinta para tratar de reconocer sus conexiones intertextuales y contextuales. El análisis nos lleva a la conclusión de que esos motivos y formas escriturales están estrechamente relacionados con cine fantástico francés de autores como Méliès, Chomón, Cohl, Deed o Linder. Estos directores, que tuvieron gran éxito durante los primeros veinte años del siglo XX, estuvieron muy influenciados por las vanguardias parisinas de finales del XIX entre las que destacaban los Incoherentes. El empleo de esos materiales textuales por parte del cineasta soviético resulta, además, perfectamente congruente con sus elaboraciones teóricas acerca del montaje de atracciones.
THE ENDANGERED CITIES OF UKRAINE
Authors: Forest Maxime , Gubkina Ievgeniia , Hatherley Owen
Published: February 2023

In June 2022, UNESCO General Director, Audrey Azoulay warned that relentless attacks on Ukrainian cultural sites must cease. Yet, those have only further intensified since and as of early November 2022, according to the count made by her organization, 212 cultural sites had been totally or partially destroyed in Ukraine, among which 92 religious sites and 94 landmark buildings, monuments or historical sites, but also 16 museums and 10 libraries. To an organization founded in 1945 upon the rubble of WWII and whose mission notably consists in protecting world tangible and intangible heritage, the return of war in Europe represents a major challenge.
PUBLISHED RESEARCH SOURCES ON UKRAINIAN AVANT-GARDE
Authors: Various
Published: February 2023

Ukrainian architecture is scarcely represented in Western libraries. And there are few Western investigations that specialize in the Ukrainian Modern Movement. For a long time, Selim Omarovich Khan-Magomedov’s book ‘Pioneers of Soviet architecture’, first published in the German Democratic Republic in 1983 as ‘Pioniere der Sowjetischen Architektur. Der Weg zur neuen sowjetischen Architektur in den zwanziger und zu Beginn der dreißiger Jahre’, has been the best known source on this subject accessible for Western scholars. In 1987, this book was translated and published in English by Thames and Hudson/Rizzoli. After the fall of the Soviet Union, Khan-Magomedov reworked his manuscript and published an enhanced Russian version in two volumes1.In this short overview of published materials on Ukrainian Avant-garde, I want to focus on almost unknown publications from the 1920s-1930s and recent research published in the last three decades.
Immediate Effect of Neural Tissue Mobilization on Tibial Nerve Mobility in Individuals with Flatfeet
Authors: A Kaydawala Batul , S Sheth Megha
Published: February 2023

Introduction: Tarsal tunnel syndrome is compression of the posterior tibial nerve as it travels through the tarsal tunnel. Individuals with flatfeet are prone to develop tarsal tunnel syndrome as there is outward tilting of heel which flattens the medial arch. Neural tissue mobilization is a manipulative technique by which neural tissues are moved and stretched either by movement relative to their surroundings or tension development. The aim of the study was to see the effect of neural tissue mobilization on tibial nerve mobility in subjects with flat feet.
Methodology: An experimental study was conducted on twenty four participants,18-30 years of age, with bilateral flatfeet by positive navicular test with no symptoms. Individuals with symptoms, severe hamstring tightness, and recent ankle sprain were excluded. Straight leg raise (SLR) was performed by therapist on one leg, till a stretching sensation distal to knee in the area of tibial nerve was observed. Once symptoms appeared double ended sliders targeting knee and ankle were given, 3 repetitions on any side. The other limb was used as a control limb. Results were noted in the form of range of motion (ROM) of SLR and compared using independent sample t test.
Result: Difference in mean SLR between both groups(19+1.3,t=6.25,p<0.001,CI=12.28 to 23.96) was statistically significant.
Conclusion: Neural tissue mobilization can be given as an intervention to improve SLR range of motion in individuals with flat feet. Further studies can be done to see prevention of compression of tibial nerve in individuals with flat feet with neural mobilization.

Key words: Flatfoot, neural tissue mobilization, tibial nerve
Reliability Analysis of a Self-Developed Elderly Well-Being Scale
Authors: Shila Mainali , Jayanti Semwal , Bibhav Adhikari
Published: February 2023

Introduction/Objective: The well-being of older people needs to be assessed periodically to plan and manage proper care. This study aimed to assess the validity and analyse the reliability of the self-developed Well-being scale to determine the suitability of the scale for identifying the well-being status of older people and evaluating effectiveness of self-structured nursing interventions.
Methods: A descriptive cross-sectional study design was used among 31 older people living in a rural community in the Kavrepalanchok district, Nepal in September 2021. A purposive sampling technique was used, and face-to-face interview in home visit was done using Self-structured Elderly Well-being Scale. The internal consistency reliability was assessed by Cronbach’s alpha and test re-test on a three and six point Likert scale.
Results: Respondents were more female (51.6%) with a mean age of 66.70 ±4.65, and 19 (61.29%) were in the age group 60-67 years. There are four domains in the well-being scale. The physical well-being scale was found to be highly reliable in Cronbach’s alpha (0.892), the test re-test method (0.9957), and the test re-test reliability was higher than Cronbach’s alpha. The psychological well-being scale was also highly reliable in Cronbach’s alpha (0.871) and test re-test method (0.9788). Similarly, the reliability of the social and spiritual well-being scale were good in Cronbach’s alpha (0.758 & 0.774) and very good in the test re-test (0.9100 & 0.8876), respectively. The inter-item reliability was also found suitable.
Conclusion: The elderly well-being scale demonstrated exemplary performance in tests of reliability and validity. It can individually assess physical, psychological, social and spiritual well-being and older people’s overall well-being in the community and institutional settings. It is a suitable tool for assessing well-being status and evaluating the effectiveness of nursing interventions.

Key words: Well-being Scale, Reliability, Cronbach’s alpha, Persons’ Correlation, Older People and Rural Community.
Non-Surgical Management of Apical Root Resorption of Maxillary Lateral Incisor with Dens in Dente - A Case Report
Authors: T D Geo , Gupta Saurabh , Saxena Payal
Published: February 2023

Dens in dente is a developmental anomaly which occurs as a consequence of invagination of external tooth surface of crown before the calcification is complete. Complexity of dens in dente ranges from invagination within the limit of cement-enamel junction to that penetrates through the root perforating at the apical area showing a ‘second foramen’ in the apical or periodontal area. Because of the bizarre root canal anatomy and associated peri apical pathology; the management of such teeth might end up with combination of endodontic-surgical intervention or extraction. This article describes the non surgical endodontic management of maxillary left lateral incisor with dens in dente, apical root resorption and periapical cyst.

Key words: Dens in dente, Dens invagination, Root resorption, Biodentine
The Magnitude of Outpatient Visits for Non-Communicable Diseases in Karnataka: A District-level Analysis
Authors: G. Hadagalimath Manjula , K. Itagi Ragini
Published: February 2023

Noncommunicable Diseases (NCDs) are the leading causes of premature deaths globally. Seven out of 10 deaths attributed to NCDs. Cardiovascular diseases, Cancer, Respiratory and Diabetes account for 82% of total NCD deaths and 54% loss in disability-adjusted life years. Additionally, the onset of NCDs declined to ≥45 years. Globally, several strategies adopted to reduce the burden of NCDs. In India, all public health facilities provide free screening, diagnosis, and treatment services under NPCDCS programme. The present study explores, proportion of outpatients visited across districts in different levels of public health facilities for NCDs in Karnataka. The magnitude of outpatients for NCDs tremendously increased in the state. A greater proportion of patients for hypertension, diabetes and epilepsy visited to PHCs. A majority of patients for oncology, acute heart disease, mental illness, and epilepsy services visited either DH/Medical Colleges or SDHs. However, previous studies shows, health facilities are not well equipped to confirm healthcare services for NCD cases. Hence, the present study suggests, there is urgent need to strengthen infrastructure, appoint specialists, and regular supply of ample medicine and diagnostics to manage critical NCD patients at all health facilities.

Key words: Hypertension, Diabetes, Oncology, Mental Illness, Public Facilities
The Effect of The Pandemic of Covid-19 On Changes in Behaviour of Transactions Using Digital Banking at Customers of Bank Syariah Indonesia KCP Padang Bulan Medan
Authors: . Ermadayani , Syarif Firman , Absah Yeni
Published: February 2023

The purpose of this study aims to determine the effect of customer transaction behaviour on using digital banking during the Covid-19 Pandemic, where the impact of transaction behaviour is assessed based on the influence of Perception of Trust, Perception of security, Perception of convenience, and Perception of benefits on the use of Digital Banking with Availability of Features as a variable moderation. The population used in this study were customers of PT Bank Syariah Indonesia (Bank BSI) KCP Padang Bulan Medan. The research sample based on multivariate analysis was 102 respondents. The method of data analysis in this study is the Instrument Test, Classical Assumption Test, Hypothesis Test in the form of a Determination Coefficient Test (R2 Test), Individual Parameter Significant Test (t-test), and Multiple Linear Regression Test, and the last is to perform Moderation Test in the form of Moderated Regression Analysis. The research data was processed using the Statistical Package for Social Science (SPSS) 23 program. The results of this study indicate that Perception of security does not affect the use of digital banking. After Moderation with the Availability of Features, the Perception of trust and the Perception of security still does not influence the use of digital banking during the Covid-19 Pandemic. However, things are different in the Perception of convenience and the Perception of benefit, which affects the usage of digital banking¸ as well. After moderation with the Availability of Features, the Perception of convenience and benefits also affects the use of digital banking during the Covid-19 Pandemic.

Keywords: Perception of trust, Perception of security, Perception of convenience, Perception of benefits, Feature Availability, Digital Banking¸ Covid-19 Pandemic.
Developing Professional Competency of Elementary School Prospective Teachers through Inductive Thinking Approach
Authors: Krisnanda Veno Dwi , Riandika M Lucky Nindi
Published: February 2023

Professional competence which is the ability to communicate with students with broad knowledge, capabilities in the use of information technology and communicative attitudes in teaching. Teacher competence can be developed through several approaches, one of which is through an inductive thinking approach in developing higher-order thinking patterns and critical thinking. This study aims to describe the application of the inductive thinking approach in an effort to develop the competencies of prospective elementary school teachers, especially professional competencies. This research method is a quantitative method using pre-experimental design. The sample in this study used 78 prospective elementary school teacher students. The instrument used is a questionnaire of professional competence of primary school teachers who have been tested for validity and reliability showing high categories. Data analysis with descriptive analysis, then using SPSS applications with comparative analysis. The results showed that there was a significant increase in the professional competence of prospective elementary school teachers through an inductive thinking approach. The conclusion of this study, an effective inductive thinking approach is used to develop the professional competence of prospective elementary teachers. The inductive thinking approach model developed in this study can be implied in elementary school teachers on a wider scale to have more impactfull on professional competence in all elementary school teachers.

Keywords: professional competency, prospective elementary school teachers’, inductive thinking approach
Geographic Information System (GIS) and Healthcare: An Overview
Authors: Yasmin Shahina , Krishna Murth Archana , KB Shilpashree
Published: February 2023

GIS (Geographic Information System) are computer-based tools used to visualize, analyze, accumulate and explicate geographic data. The determinants of health status are often correlated and analogous. Establishing GIS-based approaches and programmes can predict and analyze the complexity of web of causation of many health issues. GIS can be used to efficaciously investigate health along with its physical, social and cultural environments. Mapping functions of GIS can be used to plot health attributes for better visualization, exploration, and modeling of health patterns. GIS based healthcare helps in explaining and describing health outcomes, health disparities, healthcare access and how health care delivery can be improved. GIS can also be used to bring all spatial data under one umbrella of “Geo Data Bank” that could provide easy accessibility and help in better utility of healthcare services. In India, the adoption and use of digital spatial methods like GIS in the field of healthcare has lagged. However, the “Computer Aided Utility Mapping Project for six cities” in India is a significant benefit for the GIS users in the country which can be used by healthcare sector in the near future for the upliftment of healthcare facility. The primary focus of the paper is to provide details about benefits of using GIS-based analytical approaches in healthcare planning, the successes, challenges, remedies and future perspective of GIS in healthcare delivery.

Keywords: GIS, healthcare planning, location allocation modeling, public health, spatial analysis, spatial epidemiology.
High Risk of Obstructive Sleep Apnea in Hemorrhagic Stroke Patient
Authors: Triana Rossy , Indrasari Utami Desak Ketut
Published: February 2023

Background: Stroke is one of the biggest causes of mortality and morbidity in the world, about 10% - 20% are caused by hemorrhagic strokes. Obstructive Sleep Apnea (OSA) is a sleep disorder that is often found in 5-15% of the general population and has a high prevalence in patients with cerebrovascular disease.
Case summary: A 51 year old female with a sudden loss of consciousness since 1 day ago, while working. The patient has a history of hypertension since 2014. On computerized tomography scan (CT scan) of the head without contrast shows bleeding. During hospitalization, it appears that the patient snoring, easily falls asleep during the day and there are periods of apnea when the patient sleeps. The blood gas analysis was normal. The patient's sleep score shows high risk of OSA.
Discussion: Patient with a hemorrhagic stroke and high risk OSA. There are several risk factors that influence the emergence of OSA in this case, obesity and hypertension. The therapy is to prohibit positioning, sleep hygiene, and losing weight.
Conclusion: We have reported a case of hemorrhagic stroke with a high risk of OSA that was experienced long before. The high risk of OSA in these patients can be a risk factor for hemorrhagic stroke. Polysomnography examination needs to be done in patients with a high risk of OSA, as the gold standard. Management of these patients apart from giving pharmacological therapy combined with behavioral and positional therapy to treat OSA symptoms. Mandibular enhancement devices and continuous positive airway pressure (CPAP) have not been given to this patient because polysomnography has not been performed and cost constraints.

Keywords: hypertension; hemorrhagic stroke; obesity; OSA
Comparative Assessment of the Umbilical Artery Doppler Velocimetry and Non-Stress Test in Evaluating the Fetal Well-Being among Women with Pre-Eclampsia
Authors: Kundal Priyanka , Sami Rukhsana , Sharma Anu
Published: February 2023

Background: Pre-eclampsia is defined as a systemic syndrome characterized by the new onset of raised blood pressure >140/90 mm Hg and proteinuria after 20 weeks of gestation in a previously normotensive woman. Reduction of neonatal complications of pre-eclampsia is feasible by assessment of fetal well-being. Both fetal Doppler and NST are used for the screening of high-risk pregnancies.
Methods: It was a prospective comparative tertiary care hospital based study of pre-eclamptic women admitted in department of Obstetrics and Gynaecology, Lalla Ded hospital over a period of 18 months from March 2020 to September 2021. Written informed consent was obtained from the subjects prior to recruitment to the study. A total of 232 patients who were known case of pre-eclampsia or those who develop pre-eclampsia during hospital stay were included in our study.
Results: Both NST and fetal UA Doppler velocimetry were significantly correlated with the perinatal outcome. However; UA Doppler velocimetry had more sensitivity than NST. In contrast, NST had slightly more specificity than UA Doppler velocimetry.
Conclusion: The fetal umbilical artery Doppler velocimetry improves the sensitivity for the prediction of poor perinatal outcome when it is combined with the non-stress test. Both the tests are complimentary to one another in fetal surveillance of high risk pregnancies like pre-eclampsia.

Keywords: Pre-eclampsia, Umbilical arteries, Ultrasonography, Doppler, NST, Prenatal diagnosis
Occurrence of post-partum hemorrhage in spontaneous versus induced labor in primigravida at term in a tertiary care hospital of Peshawar
Authors: Bukhari Basirat , Shinwari Laiyla , Irfan Sarwat
Published: February 2023

Introduction: Occurrence of post-partum hemorrhage (PPH) is a serious life-threatening complication of delivery and can occur with both normal vaginal delivery as well as induced labor. It is important to define the extent of blood loss after either procedure to adopt the safer method, particularly in complicated deliveries.

Objective: To compare the occurrence of post-partum hemorrhage in spontaneous and induced labor in primigravida at term at a tertiary care hospital of Peshawar.

Materials & Methods: This descriptive cross-sectional study was performed in Obstetrics and Gynecology Department (Gynae B unit), Lady Reading Hospital, Peshawar from 31/5/2019 to 31/11/2019. Total patients observed were 134. All women were subjected to complete history taking and detailed examination. Brief obstetrical history, period of gestation, mode of onset of labor and frequency of post-partum hemorrhage (more than 500 ml after vaginal delivery) were noted. Women were induced with prostaglandin E2 gel only. The second gel was repeated after 6 hours if first attempt was failed. No more than three gels were used. Women were excluded from the study if they failed to go into labor even after the third gel. After vaginal delivery sanitary pads were used for blood loss estimation. They were weighed beforehand and after being soaked with blood, they were again weighed and the difference was noted as 1gm = 1ml. Descriptive statistics were done by SPSS 21.

Results: The mean age of subjects was 32 ± 3.90 years Forty two percent patients had BMI ≤25 and 58% patients had BMI >25. Seventy two percent of patients were having spontaneous labor and 28% were having induced labor. Twenty percent of patients had post-partum hemorrhage, 7% in spontaneous labor while 44% in induced labor, showing significant difference (p=0.03).

Conclusion: Post-partum hemorrhage occurred significantly more frequently in primigravid women at term undergoing induction of labor as compared to spontaneous labor.
ЧИСЛЕННАЯ ОЦЕНКА ПРЕДЕЛЬНЫХ НАГРУЗОК ДЛЯ ГИБКИХ НИТЕЙ В УПРУГОПЛАСТИЧЕСКОМ СОСТОЯНИИ
Authors: Tarasov Denis Aleksandrovich
Published: February 2023

Рассмотрена одна из основных проблем, возникающих при обследовании зданий и инженерных сооружений, связанная с определением несущей способности разного рода конструкций. Поставлена задача по оценке предельных нагрузок способных воспринимать конструктивными элементами, исходя из требований прочности и жесткости на изменившиеся условия эксплуатации с учетом реальных свойств материала. В качестве объекта исследования рассматриваются элементы, обеспечивающие общую прочность покрытий общественных зданий и инженерных сооружений, расчетной моделью которых является гибкая нить. Сформулированная цель достигается с помощью разработанной методики численного моделирования путем ре-шения задачи условной оптимизации. Проведена оценка адекватности результатов, получаемых с помощью разработанной методики, посредством выполнения тестовых задач и сопоставления с данными, полученными общепризнанным методом конечных элементов.
РАЗВИТИЕ ТЕОРЕТИЧЕСКИХ И МЕТОДОЛОГИЧЕСКИХ ПОДХОДОВ ПРИ ИЗУЧЕНИИ ТЕОРЕТИЧЕСКОЙ МЕХАНИКИ СТУДЕНТАМИ СТРОИТЕЛЬНЫХ СПЕЦИАЛЬНОСТЕЙ
Authors: Ponomareva Yelena Vladimirovna , Khokhlova Olga Aleksandrovna , Kulemina Kseniya Vladimirovna , Sinelshchikov Aleksey Vladimirovich
Published: February 2023

Современные реалии ставят перед системой высшего профессионального образования проблему обеспечения регионов квалифицированными строителями, способными самостоятельно овладевать профессиональными видами деятельности, обладать мультидисциплинарным системным мышлением. Подготовка будущих специалистов осуществляется в процессе изучения естественнонаучных дисциплин и дисциплин общепрофессионального цикла, в том числе теоретической механики, преподавание которой в современном вузе сопряжено с определенными трудностями: 1) дисциплина является достаточно сложной для восприятия студентами начальных курсов; 2) резкое сокращение числа аудиторных часов вызывает необходимость оптимизации учебного процесса даже при очном обучении. Такое положение вещей обуславливает потреб-ность в создании эффективных интерактивных средств дистанционного обучения, направленных на организацию самостоятельной работы студентов. В большинстве случаевпри использовании интерактивных средств по теоретической механике отсутствуют возможности: 1) адаптации материала по заданным критериям для обеспечения требуемого уровня сложности и объема изучения; 2) разработки и внедрения принципиально новых расчетных заданий, ориентированных не только на формирование базовых теоретических знаний, но и на приобретение навыков решения задач, тесно связанных с будущей профессией. Авторами предложено применение специализированных математических пакетов, а также ориентация излагаемого материала на будущую профессиональную деятельность студентов и укрепление связей дисциплин механического профиля. Разработана методология проведения расчетов статических и прочностных параметров механических систем (твердых тел, составных конструкций, ферм) в системах Maple и MathCAD. Сформиро-ван комплекс программ, используемый как генератор уникальных многовариантных расчетных профориентированных заданий, ранжируемых по степени сложности. Отдельные положения предложенной методики встречаются в работах отечественных авторов, однако в настоящее время аналога, реализующего в полном объеме интерактивное средство дистанционного обучения, способное решать образовательные и научно-практические задачи, генерировать задания определенной сложности с автоматической проверкой получа-емых результатов, формировать банк уникальных многовариантных профориентированных расчетных заданий, не существует.
ГРАДОСТРОИТЕЛЬНОЕ ПРЕОБРАЗОВАНИЕ ТЕРРИТОРИИ
АРКТИЧЕСКОЙ ЗОНЫ РОССИЙСКОЙ ФЕДЕРАЦИИ: НОВЫЕ ПОДХОДЫ И РЕШЕНИЯ
Authors: Sotnikova Olga Anatolyevna , Khaleyeva Tatyana Sergeyevna , Salasin Yevgeniy Andreyevich
Published: February 2023

В статье рассматривается отечественный опыт градостроительного освоения территорий Арктической зоны Российской Федерации, на основании которого предлагаются современные подходы и концепции, затрагивающие различные отрасли человеческой деятельности. Приводится оценка существующей ситуации в системе расселения и действующих градообразующих отраслей экономики региона с предпосылками фор-мирования патерналистской модели освоения. Материалы статьи посвящены ретроспективному анализу проектов компактных градообразований для Арктики на примере разработок советских и российских архитекторов. Рассмотрены примеры реализации современных концепций автономных военных баз. В рамках обзора градостроительных тенденций кафедрой проектирования зданий и сооружений им. Н. В. Троицкого Воронежского государственного технического университетапредложены наработки градостроительных концепций создания патерналистских моделеймикропоселений с общественными пространствами, включающими в том числе образовательные и медицинские центры для Арктической зоны.
Detección molecular de coinfección por Ehrlichia canis y Ehrlichia ewingii en un perro en Ecuador
Authors: Chalco-Torres Lorena Elizabeth , Guerrero-López Ana Elizabeth , Sánchez-Prado Robert Gustavo , Pérez Rodríguez Jhonny Edgar , Oliveira Claudio , Gómez Juan Antonio , Lenin-Aguilar Fernando , Nirchio-Tursellino Mauro
Published: February 2023

Se presenta el estudio de un perro con sintomatología de Parvovirosis que resultó positivo a los test de inmunocromatografìa para Parvovirus y Ehrlichia canis el cual fue confirmado, a nivel molecular, como positivo para E. canis y E. ewingii. Además del interés que representa este caso desde el punto de vista clínico, la detección mediante PCR de E. ewingii sugiere la presencia de este patógeno fuera de su rango de distribución geográfica natural (México, Guatemala, Guyana, Guayana Francesa y Estados Unidos) y destaca la necesidad de realizar estudios moleculares en garrapatas locales a fin de verificar si éste es un caso aislado en Ecuador o si, por el contrario, existe colonización de E. ewingii en vectores locales.
Minerals and Glucose Among Patients With Vitamin (D) Deficiency
Authors: Fadul Idris Omer , Kamaleldin Altayeb Abdelraheem Mohammed
Published: February 2023

According to previous studies, vitamin D deficiency might increase the risk of mineral deficiency, and type 2 diabetes mellitus. The aim of this study was to evaluate the level of calcium, phosphorus, calcium to phosphorus ratio, magnesium, and fasting blood glucose in blood serum of patients with vitamin D deficiency. This case-control study comprised 71 patients, 30 subjects sufficient in vitamin D classified as control group (Mean value of vitamin D was 30.67. ± 5.94 ng/dl), and 41 patients suffering from vitamin D deficiency, and insufficiency chosen as the case group (Mean value of vitamin D was 9.79 ± 3.12 ng/dl) .There was lower significant difference in the level of calcium (Ca), calcium–to-phosphorus ratio (Ca/P), and magnesium (Mg) in cases compared to control,  but there was higher significant difference in the level of phosphorus (P), and  fasting blood glucose (FBG) in cases compared to controls. Serum vitamin D levels showed significantly positive correlations with Ca, and Ca/P ratio, and negative correlation with P. However, vitamin D demonstrated insignificant positive correlation with Mg, and insignificant negative correlation with FBG. The study concluded that, vitamin D deficiency associated with diabetes risk, in addition to mineral deficiency, which associated with various disorders, such as skeletal deformities, osteoporosis, Osteomalacia, cardiovascular diseases, and metabolic syndrome.
حكم نبش القبور وصوره المعاصرة: دراسة فقهية
Authors: الحوسني ياسر حسن شهاب , النقبي سعيد سليمان العقيد
Published: February 2023

المستخلص :

يتناول هذا البحث دراسة مسألة فقهية معاصرة وهي: حكم نبش القبور وصوره المعاصرة، حيث تقرر في الشرع تحريم نبش قبور الموتى إلا لمسوغ صحيح، وقد ذكر الفقهاء بعض الحالات التي يسوغ فيها نبش القبر، لكن استجد في هذا العصر حالات ينبش فيها القبر، فهل تعد هذه الحالات المستجدة المعاصرة من الحالات التي يشرع فيها نبش القبر أم لا ؟

يهدف الباحثان من هذا البحث بيان الحكم الشرعي للصور المعاصرة لنبش القبور؛ وجمع هذه الأحكام ولم شتاتها، في بحث مستقل.

وقد تناول البحث حكم نبش القبر لغرض صحيح ولغير غرض صحيح، والأعذار المسوغة التي ذكرها الفقهاء لنبش القبر، وضوابط عامة للحالات التي يجوز فيها نبش القبور، ثم تناول البحث ثلاث نوازل فقهية معاصرة لنبش القبر؛ وهي: استخراج الميت من قبره لغرض التشريح الجنائي، نبش القبور للمشاريع العمرانية، نبش القبور في المقابر الجماعية.

توصل الباحثان إلى عدد من النتائج؛ كان من أهمها: مراعاة الشرع لحقوق الإنسان حياً كان أو ميتاً، والموازنة بين مصلحة الميت والحي وفق ضوابط شرعية تكفل تحقيق العدالة في الأرض.

يوصي الباحثان بأهمية تشكيل لجان شرعية تعرض عليها الحالات التي تتطلب نبش القبور لدراستها وإصدار الفتوى المناسبة لكل حالة.

سلك الباحثان في تناول مسائل هذا البحث المنهج الاستقرائي، والمنهج التحليلي المقارن، والمنهج الاستنباطي.
Study on Chemical Composition Properties of Raw Camel’s Milk Produced in Khartoum State, Sudan
Authors: Elrofai Amna S. , Elrofaei Nagat A.
Published: February 2023

Abstract

The study was carried out to assess the chemical composition of raw camel’s milk produced in Khartoum State, Sudan in summer and winter seasons.

30 samples of the raw camel’s milk were taken from five different areas ( El _ Sarha , El_ Hatana , Soog Libya , Om Dawn Ban and Shambat ) . 15 samples were taken in May , 2017 and 15 samples in February , 2018 . The results obtained in two seasons ( summer and winter ) ,respectively as the following :-

The results of chemical composition which obtained in summer were pH (5.6 – 6.6) ,density (18 – 29) , fat content (2.3 – 3.5%) , protein content (6.1 – 8.4%) , ash content (0.4 – 0.9%) , lactose content (2.5 – 3.5%) , and total solids ( 10 . 1 – 14.3% ) ,whereas the values of the chemical composition that obtained were (4.6 – 6.6 ) , (15-29) , (4.5 – 5.0 %) , (2.5 – 3.5%) , (0.7 – 0.8 %) , (4.4 – 5.7%) and  (8.2 – 15 .2%) for the above mentioned parameters , respectively.
ANALISIS PERFORMA PRESSURE TEST SEPARATOR PADA METODE DIRECT SYNTHESIS DAN ZIEGLER NICHOLS
Authors: Ulfa Auliya , Hamdani Chalidia Nurin
Published: February 2023

Test Separator V-94-203 di SPG Kuang merupakan separator yang berfungsi untuk menguji kandungan gas pada sumur – sumur yang ada di SPG Kuang sebelum gas masuk ke gas scrubber. Gas keluaran dari Test Separator V-94-203 ini perlu dikendalikan agar proses tetap berjalan dengan baik sehingga dilakukan analisa respon transient dan tuning PID controller menggunakan metode tuning Direct Synthesis dan Ziegler Nichols. Berdasarkan grafik respon kedua metode tersebut didapatkan hasil bahwa metode Direct Synthesis memiliki grafik respon yang lebih cepat dari kondisi aktual dan tidak memiliki overshoot sedangkan metode Ziegler Nichols memiliki grafik respon yang sangat cepat namun memiliki overshoot yang sangat besar. Setelah melakukan tuning kemudian dilakukan analisa kestabilan yang menunjukkan bahwa sistem dari hasil tuning Direct Synthesis memiliki sistem yang stabil. Hasil analisa respon dan kestabilan ini menunjukkan bahwa tuning Direct Synthesis memiliki respon yang lebih baik dari kondisi aktual dan memiliki sistem yang stabil sehingga bisa diterapkan pada controller PIC-9411.
ANALISA BOP SISTEM PADA PEKERJAAN WORK OVER DAN WELL SERVICE SUMUR X DI RIG Y PT PDSI
Authors: Gunawan Jefri
Published: February 2023

BOP System merupakan salah satu dari lima sistem utama dalam suatu kegaiatan pemboran, mencegah terjadinya kick dan sebagai sistem untuk menutup lubang bor ketika terjadinya blowout. Dengan memantau dan mengontrol ketidaksetabilan aliran dan tekanan minyak dan gas saat pemboran. Sistem ini juga digunakan pada kegiatan Work Over (WO) dan Well Service (WS). Karena fungsinya yang sangat krusial. Penelitian ini dimaksudkan untuk menganalisa dan memahami spesifikasi serta permasalah yang sering dihadapi di sebuah sistem BOP guna membuat suatu perencaanan perawatan BOP yang sesuai. Untuk mendapatkan data, maka perlu diadakan beberapa tes. Diantaranya adalah wellbore test, function test, pressure test, dan hydraulic tes. Tes dilakukan, salah satunya bertujan untuk, juga digunakan untuk mengetahui parameter kerja yang dimiliki oleh suatu BOP. Seperti menghitung kapasitas bottle dari accumulator unit dan kapasitas accumulator unit itu sendiri. Perhitungan tersebut kmeudian digunaakan untuk mengetahui parameter minimum untuk suatu accumulator unit dapat bekerja. Karena fungsinya sebagai pengaman, maka suatu sistem BOP harus memiliki spesifikasi yang lebih besar dari parameter sumur yang mungkin terjadi. Seperti tekanan kerja dan kapasitas dari suatu rangkaian sistem BOP atau accumulating unit pada suatu lapangan. Hal ini dimaksudkan sebagai safety factor dari suatu kegiatan. Baik WO/WS maupun pemboran
PERHITUNGAN KAPASITAS RIG PADA OPERASI WELL INTERVENTION SUMUR N BERDASARKAN BEBAN HOISTING SYSTEM
Authors: Syafeiy Asep Irawan , Suranta Bambang Yudho
Published: February 2023

Well intervention merupakan suatu pekerjaan yang bertujuan untuk melancarkan serta meningkatkan kembali produksi pada sumur minyak dan gas dengan harapan pada operasinya berlangsung aman tanpa terjadinya masalah sehingga mampu menghemat waktu serta biaya. Pemilihan kapasitas rig menjadi faktor penting untuk menunjang kesuksesan suatu operasi pengeboran. Pada operasi pengeboran atau perawatan sumur perlu diperhitungkan berat string, perhitungan drag, perhitungan beban maksimum, perhitungan kapasitas hook load, horse power guna menaikkan maupun menurunkan rangkaian, serta beban total yang bekerja pada menara agar beban yang harus ditanggung atau ditahan oleh drawwork serta menara mampu untuk menahan rangkaian peralatan. Berdasarkan pada perhitungan untuk sistem pengangkatan didapat berat beban maksimum yang akan bekerja di sumur “N” sebesar 123.812,96 lbs atau hanya 61,9 persen dari kapasitas maksimal, beban yang akan di topang pada sumur “N” dapat dikategorikan aman karna tidak melebihi kapasitas maksimal dari rated static hook load sebesar 200.000 lbs dan horse power yang digunakan pada sumur “N” tidak lebih dari HP yang sudah disediakan oleh rig yaitu hanya sebesar 230,8 HP atau hanya 65,7 persen dari total HP drawwork.
Optimalisasi Unjuk Kerja Pompa Sentrifugal P1302 di PT Petrokimia Gresik
Authors: Rivaldy Rian Aditya , Mulyono Dwi
Published: February 2023

PT. Petrokimia Gresik merupakan salah satu perusahaan industri yang bergerak dibidang agraris. Untuk menunjang peran suatu industri yang sangat penting ini banyak equipment yang digunakan sehingga fungsi ini dapat berjalan dengan lancar, pompa merupakan alat yang memegang peranan penting dalam pendistribusian fluida didalam suatu produksi. Pompa P1302 di PT. Petrokimia Gresik ini merupakan salah satu pompa yang critical karena berfungsi sebagai pompa yang digunakan untuk memompakan Sulfuric Acid  dari tanki D-1301 ke tanki T-1302. Di dalam evaluasi unjuk kerja pompa parameter yang dievaluasi meliputi kapasitas,head pompa, efisiensi serta NPSHa, data tersebut didapatkan melalui data sheet dan manual book. Setelah dilakukan evaluasi maka didapatkan penurunan kapasitas aktual sebesar 865 m3/hr dari kapasitas desain yaitu sebesar 1100 m3/hr. Head aktual mengalami penurunan sebesar 20,69 m dari  head desain yaitu sebesar 25,23 m. Dimana Efisiensi Pompa mengalami penurunan dari efisiensi desain sebesar 70 persen menjadi 62 persen pada efisiensi aktual. untuk NPSHa mengalami kenaikan sebesar 5,94 m dari pada angka NPSHr atau desain sebesar 5 m, langkah yang diambil untuk memenuhi kapasitas produksinya yaitu melakukan optimalisasi dengan menaikkan putaran dari 1350 rpm ke 1480 rpm hal ini berdampak terhadap kapasitas dimana dari kapasitas aktual sebesar 865 m3/hr naik menjadi 948,29 m3/hr, Head pompa juga mengalami perubahan dimana head aktual sebesar 20,69 m naik menjadi 24,49 m, sedangkan daya pompa mengalami kenaikan dari 141,57 kw menjadi 186,53 kw, Efisiensi yang semulanya  62 persen sedikit mengalami penurunan tetapi tidak signifikan yaitu sebesar 61,26 persen.
EVALUASI ELECTRIC SUBMERSIBLE PUMP UNTUK MENGETAHUI LAJU PRODUKSI OPTIMUM PADA SUMUR Y
Authors: Djumpa Azzah Karimah , Candra Arya Dwi , Rosiani Diyah
Published: February 2023

Sumur yang sudah tidak bisa berproduksi secara natural, menggunakan metode yang disebut Artificial Lift atau pengangkatan buatan dalam proses produksi minyak dan gas nya. Ada berbagai jenis metode pengangkatan buatan, namun salah satu metode pengangkatan buatan yang digunakan di setiap lapangan sumur PT.Citic Seram Energy Limited Oseil adalah electric submersible pump. Hal ini dikarenakan rata-rata kedalaman bor di lapangan Oseil merupakan sumur yang cukup dalam dengan tipe sumur terarah. Oleh karena itu, penulis harus menganalisis kinerja pompa electric submersible pump dengan melihat kurva Inflow Performance Relationship (IPR) untuk menentukan laju optimal sumur Oseil-X. Kurva hubungan kinerja inflow dapat dilihat dari hubungan antara jalur aliran fluida dengan tekanan aliran bottom hole (Pwf). Untuk sumur Oseil-X sendiri, kurvanya adalah kurva hubungan arus-daya dua fasa. Hal ini terlihat dari nilai tekanan reservoir dan Pwf sumur Oseil-X lebih kecil dari tekanan titik didih . Dari perhitungan inflow performance ratio dapat diketahui bahwa debit maksimum cairan kemudian dibandingkan dengan nilai outflow optimal dan dievaluasi. Nilai flow optimal yang didapat adalah 263,4 BFPD, dengan flow rate yang dihasilkan oleh pompa yang terpasang hanya sebesar 211, sehingga dinilai kurang efisien dan perlu dilakukan penjadwalan ulang oleh perusahaan di masa yang akan datang.
Cocoons, Fungi, Nematodes, Rhizoids, Annelids, Eggs, Arthropoda in Gale Crater, Mars?
Authors: Joseph R. Gabrial , Wickramasinghe N. Chandra , A. Armstrong Richard , Duvall David , Schild Rudolph
Published: February 2023

White and dark gray oblong-ovoid cocoon-egg-like forms (“cocoon-eggs”), less than a mm in diameter, many with a single hole in one end, and some with unidentifiable specimens protruding from (exiting or entering) these holes, were photographed on mudstone in Gale Crater, Mars, on Sol 1302. If biological some of these cocoon-eggs may be frozen, fossilized or have already “hatched” or undergone metamorphosis. Specimens resembling segmented and tubular worms and rhizoids and those with multiple appendages (Arthropoda) were also photographed on these and other substrates on Mars, including on Sols 130, 132, 302, 551, 553, 808, 809, 868, 906, 1280, 1921, in Gale Crater. Many Sol 1302 “cocoon-eggs” are embedded in substrate that appears to consist entirely of a coral-stromatolite-like mass of worm- and larvae-like forms; and similar worm and segmented larvae forms appear in the interior of three semi-transparent ovoid structures. Embedded in the soil surrounding these “cocoon-eggs” are numerous concave patches reminiscent of dried “egg-yolk,” cocoon remnants or fungus, and that may represent the final stage of “cocoon” collapse and disintegration; or they are fungal in origin. Some of the segmented and tubular worm-like forms may include rhizoids and tubular fungi. Ovoids with open apertures may be evidence of fungal sporing. The possibility that fungus and diverse species and their “cocoons” share the same substrate is supported by what appears to be cyanobacteria, worms, insecta (arthropoda), and stalks topped by ovoids or ovoid-shaped microbialite-like sediment. Fungi, lichens, cyanobacteria, stromatolites and arthropoda have been previously reported in other areas of Gale Crater, whereas fungal “puffballs” and specimens attached to rocks with stalks and topped with mushroom-like caps have been observed in Meridiani Planum. The possibility these specimens are abiogenic cannot be ruled out. The evidence, in our view, arguably supports the hypotheses that various organisms colonized Mars in the ancient or recent past.
The Molecular Mechanisms underlying the Therapeutic Effect of Berberine in Inflammatory Skin Diseases
Authors: Andoh Tsugunobu , Shimizu Tadamichi
Published: February 2023

Clinical therapy of chronic inflammatory skin diseases such as atopic dermatitis is extremely difficult. Recently, the use of a number of traditional herbal medicines has been attempted to treat these skin diseases. Orengedokuto is a traditional herbal medicine consisting of four crude natural medicines, and in the field of dermatology, it is used to treat skin diseases accompanied by inflammation and pruritus. Our recent animal study showed that berberine, a major component of Orengedokuto, improves skin inflammation and itching in mice with atopy-like dermatitis. Furthermore, we identified EIF3F and MALT1 as factors involved in the suppression of cytokine production by berberine. In addition, berberine also activates AMP-activated protein kinase, which is involved in the expression of inflammatory and anti-inflammatory cytokines. In addition, berberine also attenuates epidermal hyperplasia though the inhibition of CDC6 expression. Taken together, these findings indicate that berberine improves inflammatory skin diseases by controlling gene expression related to both inflammation, anti-inflammation and keratinocyte hyperproliferation.
Simultaneous Estimation of Scopoletin, Bacopaside-II, Bacopasaponin-C, Withanolide-A, and Withanoside-IV in a Clinically Proven Polyherbal Formulation for Treatment of Insomnia
Authors: Kolhe Sanman , Yewale Sadanand , Kolsure Pramod , Dhavale Shrikant , Padmanabhan Sriram
Published: February 2023

The present work is aimed to develop and validate a reverse phase high performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of Scopoletin, Bacopaside-II, Bacopasaponin-C, Withanolide-A, and Withanoside-IV in a proprietary polyherbal formulation containing Bacopa monnieri (Brahmi), Convolvulus pluricaulis (Shankhapushpi), Withania somnifera (Ashwagandha), Nardostachys jatamansi (Jatamansi), Myristica fragrans (Jatiphal) and Valeriana wallichii (Tagar) extracts intended for the treatment of insomnia. The HPLC analysis was performed on a Inertsil ODS, 3V, 250 x 4.6 mm x 5µm, C18 column using 0.1% orthophosphoric acid buffer as the mobile phase (solvent A) and acetonitrile (solvent B) with the gradient: 0-5 min, 10-20% B; 5-10 min, 20-30% B; 10-25 min, 30% B; 25-30 min, 30-40% B; 30-40 min, 40% B; 40-45 min, 40-60% B; 45-48 min, 60% B; 48-50 min, 60-30% B; 50-52 min, 30-10% B and 52-55 min, 10% B at a flow rate of 0.8 ml/min. The detection wavelength was chosen at 227 nm for Withanoside-IV and Withanolide-A, for Scopoletin, Bacopaside-II and Bacopasaponin C, it was 205 nm. The HPLC method was validated as per ICH guidelines for linearity, LOD and LOQ. The calibration curve of all the five phytomarkers showed excellent linear correlation coefficients with values (r2=0.996) for Scopoletin, (r2=0.995) for Withanoside-IV, (r2=0.996) for Withanolide-A, (r2=0.996) for Bacopaside-II and (r2=0.999) for Bacopasaponin-C. Limits of detection (LOD) were 0.04, 0.43, 0.35, 0.39 and 0.18 μg/ml and limits of quantification (LOQ) were 0.12, 1.29, 1.06, 1.18 and 0.54 μg/ml for Scopoletin, Withanoside-IV, Withanolide-A, Bacopaside-II and Bacopasaponin-C respectively. The developed HPLC method showed good separation of all the five constituents, enabling efficient analysis of Scopoletin, Withanoside-IV, Withanolide-A, Bacopaside-II, and Bacopasaponin-C in the polyherbal formulation
Mechanistic Study of the Herbal Drug FDY003 for the Treatment of HER2-Positive Breast Cancer via Network Pharmacology Analysis
Authors: Lee Ho-Sung , Lee In-Hee , Park Sang-In , Lee Dae-Yeon
Published: February 2023

Human epidermal growth factor receptor 2 (HER2)-positive breast cancer (HER2PBC), a subset of breast cancer (BC), results from overexpression and hyperactivation of the oncogene HER2. This subtype is observed in 20-30% of all patients with BC. FDY003 is an herbal prescription comprising Lonicera japonica Thunberg, Artemisia capillaris Thunberg, and Cordyceps militaris, and its suppressive effects on HER2PBC cells have been previously investigated. However, its anticancer mechanisms, and specifically its actions on HER2PBC cells, have not been fully elucidated. Thus, we applied network pharmacology (NP) methodology to FDY003, a widely used technique that effectively and comprehensively investigates the pharmacological features of herbal drugs, to explore its mechanisms against HER2PBC. FDY003 exhibited inhibitory activity on HER2PBC cell viability, and it improved the efficacy of the HER2-targeting therapeutic. NP analysis identified 8 bioactive ingredients and 69 HER2PBC-associated genes that were targeted by those ingredients. Gene ontology analysis of the HER2PBC-associated genes targeted by FDY003 indicated that FDY003 might exhibit pharmacological effects by regulating the behaviors of HER2PBC cells, such as proliferation/growth arrest and survival/death. Moreover, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that FDY003 might affect critical pathways responsible for HER2PBC pathology, including the ErbB, HIF-1, JAK-STAT, MAPK, p53, PD-L1/PD-1, PI3K-Akt, Ras, TNF, and VEGF cascades. The NP analysis results suggested multitarget-multipathway regulatory characteristics of FDY003 against HER2PBC, focusing on its network mechanisms.