bluuebunny/crossref_metadata_2025 huggingface dataset:
Design, Synthesis, Molecular Docking Studies and Antitubercular
Evaluation of Hexahydroquinolin-2-yl Benzamide Derivatives
Authors: Babu N. Raghavendra , Koteswara Rao G.S.N. , Alavala Rajasekhar Reddy , Soukya P.S. Lakshmi
Published: July 2021

A new series of hexahydroquinolin-2-yl benzamide derivatives (BZ1-10) were designed and synthesized.
The synthesized compounds were characterized by 1H NMR, IR and ESI-MS spectra and also subjected
for molecular docking studies with the target DNA gyrase enzyme (PBD ID: 4B6C). The molecular
docking results of synthesized derivatives indicated the best docking score of -5.105 and -5.02 for BZ9
and BZ4, respectively. All the synthesized compounds were screened for antitubercular activity against
H37RV strain, among all, two compounds exhibited significant activity at 12.5 μg/mL and 25 μg/mL
concentrations. Thus, the MIC values are in between range of 12.5 and 6.25 μg/mL concentrations.
The teratogenicity assay of synthesized compounds was performed in zebrafish larvae, out of the ten
compounds, BZ4, BZ6 and BZ8 compounds were found to safer at 0.5 μM concentration without any
abnormalities.
Obesity is the basis of metabolic syndrome
Authors: Verbovoy A. F. , Verbovaya N. I. , Dolgikh Yu. A.
Published: July 2021

Metabolic syndrome is a symptom complex that is based on visceral obesity and insulin resistance. Its prevalence is quite high, which is a big problem, since this condition increases the risk of developing cardiovascular diseases and mortality from them. Metabolic syndrome includes, in addition to abdominal obesity, arterial hypertension, disorders of carbohydrate, lipid and purine metabolism. Visceral adipose tissue plays a key role in the formation of insulin resistance and other components of the metabolic syndrome. This is due to the fact that abdominal fat, in contrast to subcutaneous fat, synthesizes pro-inflammatory cytokines, as well as adipokines — adipose tissue hormones that are involved in the formation of insulin resistance, affect carbohydrate and fat metabolism and the cardiovascular system. These include leptin, adiponectin, resistin, apelin and others. Some adipokines have an adverse effect on metabolism and increase cardiovascular risks, while others, on the contrary, have a positive effect. Taking into account their role in the development of the components of the metabolic syndrome, the possibilities of a therapeutic effect on the hormones of adipose tissue to improve metabolic processes and prevent complications associated with it are discussed.
Decentralization, teacher quality, and the education of English learners: Do state education agencies effectively prepare teachers of Els?
Authors: Leider Christine Montecillo , Colombo Michaela , Nerlino Erin
Published: July 2021

English learners are entitled to participate meaningfully and equally in educational programs. The Every Student Succeeds Act (ESSA) includes provisions to ensure success for all students, including English learners. However, the federal government does not prescribe specifically how states should meet these provisions; instead, it is the responsibility of states to develop respective plans of action. This decentralization means that states play a primary role in setting policy for teacher credentialing. In this paper, we address the following question: Do state education agencies effectively prepare teachers of ELs? We reviewed the teacher credentialing requirements to teach classified English learners in bilingual education, English language development, and sheltered English immersion settings, as well as the professional teaching standards for reference to culturally and linguistically diverse learners across the 50 states and the District of Columbia. We found inconsistencies across the US with regard to the education of classified English learners and document wide variation in teacher certification for working with English learners. We highlight implications for policy and teacher preparation.
A human ex vivo coculture model to investigate peritoneal metastasis and innovative treatment options
Authors: Mönch Dina , Koch Jana , Maaß Annika , Janssen Nicole , Mürdter Thomas , Renner Philipp , Fallier-Becker Petra , Solaß Wiebke , Schwab Matthias , Dahlke Marc-H. , Schlitt Hans J. , Leibold Tobias
Published: July 2021

Objectives

Peritoneal metastasis (PM) is commonly observed in patients with colorectal cancer (CRC). The outcome of these patients is poor, with an average survival of only six months without therapy, which requires a better understanding of PM biology and new treatment strategies.

Methods

We established and characterized a human ex vivo peritoneal model to investigate the mechanisms of peritoneal seeding and possible treatment options. For this, CRC cell lines and patient-derived tumor organoids were cultured together with human peritoneum to investigate the invasion of malignant cells and the effects of local chemotherapy.

Results

Fresh human peritoneum was cultured for up to three weeks in a stainless steel ring system, allowing for survival of all peritoneal structures. Peritoneal cell survival was documented by light microscopy and immunohistochemical staining. Further, immunohistological characterization of the tissue revealed CD3-positive T-lymphocytes and vimentin-positive fibroblasts within the peritoneum. In addition, extracellular matrix components (collagens, matrix metalloproteinases) were localized within the tissue. Coculture with CRC cell lines and patient-derived CRC organoids revealed that cancer cells grew on the peritoneum and migrated into the tissue. Coculture with CRC cells confirmed that hyperthermal treatment at 41 °C for 90 min significantly enhanced the intracellular entry of doxorubicin. Moreover, treatment with mitomycin C under hyperthermic conditions significantly reduced the amount of cancer cells within the peritoneum.

Conclusions

This human ex vivo peritoneal model provides a stringent and clinically relevant platform for the investigation of PM and for further elucidation of possible treatment options.
Radioiodinated esomeprazole as a model for peptic ulcer localization
Authors: Sanad M. H. , Eyssa H. M. , Gomaa N. M. , Marzook F. A. , Bassem S. A.
Published: July 2021

This work focuses on tracking stomach ulcer localized in mice. High labeling yield and radiochemical purity were achieved for the formation of a [125I]esomeprazole radiotracer at optimum conditions of oxidizing agent content (chloramines-T (Ch-T), 100 μg), substrate amount (Esom, 100 μg), pH of reaction mixture (6), reaction time (30 min) and temperature (37 °C), using radioactive iodine-125 (200–450 MBq). The radiolabeled compound, [125I]esom, was stable in serum and saline solution during 24 h. Esom is acting as a histamine-2-receptor antagonist (H2RA). Biodistribution studies were carried in normal and ulcerated mice. High uptake of 78.12 ± 0.80% injected dose/g organ (ID/g) observed in ulcerated mice confirmed the suitability of [125I]esomeprazole as a novel radiotracer for stomach imaging.
The role of A268V exon-7 polymorphism of PPARA in development of axial spondyloarthritis
Authors: Akbulut Ekrem , Yolbas Servet , Ozgen Metin
Published: July 2021

Objectives

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that mainly affects the axial skeleton. Peroxisome proliferator activated receptor alpha (PPARA) is an intracellular transcription factor, which play a role in inflammation and osteoblasting activity. This study is designed to investigate the relationship of NG_012204.2:p.Ala268Val polymorphism of PPARA with axSpA risk and its role in disease development.

Methods

This study was conducted with 168 patients and 181 controls. Genotyping was done with MALDITOF. Gene expression level was analyzed by quantitative real time PCR (RT-qPCR). The protein homology models of PPARA were created with ProMod3. Ligand binding dynamics were tested using the AutoDock4 docking program. Statistical evaluations were made with SPSS (ver24) and GeneGlobe.

Results

Our results showed that C>T polymorphism causing NG_012204.2:p.Ala268Val change was associated with disease risk (p=0.024) and T allele increased disease risk 1.7 times (95% CI=1.070–2.594). PPARA expression decreased (p<0.05) in individuals carrying the T allele. We determined that the ligand entry pocket was opened 1.1 Å in the polymorphic PPARA. Polymorphic change caused a decrease in the ligand binding affinity.

Conclusions

Our results provide an important contribution to elucidating the development of axSpA and demonstrate the potential of PPARA as a marker for the diagnosis of axSpA.
From RHAM to RHNA and Beyond
Authors: Phillips Eric S.
Published: July 2021

The State of California’s main tool for housing planning is legislation mandating a “Housing Element” as a component of all cities’ and counties’ comprehensive plans. Each local jurisdiction must demonstrate how it can meet the state’s calculated “Regional Housing Needs Allocation (RHNA). The article traces the roots of this state requirement from an earlier Regional Housing Allocation Model (RHAM), which was merely a guideline. To ensure compliance, the legislature barred courts from intervening in the RHNA process. Nevertheless, it has taken four decades for California’s local jurisdictions to adopt legally adequate Housing Elements.
Mechanical properties of Ficus vallis-choudae (Delile), a lesser utilized species in Nigeria
Authors: Aguda Lawrence , Ajayi Babatunde , Areghan Sylvester , Olayiwola Yetunde , Kehinde Aina , Idowu Ademola , Aguda Yetunde
Published: July 2021

Declining availability of the prime economic species in the Nigerian timber market has led to the introduction of Lesser-Used Species (LUS) as alternatives. Their acceptability demands information on the technical properties of their wood. The aim of this study was to investigate the mechanical properties of Ficus vallis-choudae to determine its potential for timber. Three mature Ficus vallis-choudae trees were selected and harvested from a free forest area in Ibadan, Oyo State, Nigeria. Samples were collected from the base (10%), middle (50%), and top (90%) along the sampling heights of each tree, which was further partitioned into innerwood, centrewood, and outerwood across the sampling radial position. Investigations were carried out to determine the age, density, moisture content, impact strength, modulus of elasticity, modulus of rupture, compressive strength parallel-to-grain, and shear strength parallel-to-grain. The mean impact bending strength, modulus of rupture, modulus of elasticity, maximum shear strength parallel-to-grain, and maximum compression strength parallel-to-grain for Ficus vallis-choudae at 12% moisture content were 20.4 N/mm2, 85.8 N/mm2, 709 N/mm2, 10.7 N/mm2, and 33.6 N/mm2, respectively. The study found the species to be dense with high strength properties in comparison with well-known timbers used for constructional purposes.
Effect of liquid hot water pretreatment on selected properties of rice husk and its particleboard
Authors: Luo Peng , Yang Chuanmin , Li Mengyao , Wang Yueqi
Published: July 2021

Rice husk has a water repellent wax layer on its surface and has high pH and buffering capacity, which inhibit surface adhesion and result in the poor strength and water resistance of rice husk particleboard bonded with water-borne urea formaldehyde (UF) resin. In this work, rice husks were pretreated with liquid hot water at different temperatures (130, 140, 150, and 160 °C) and residence times (10 and 20 min). Pretreated rice husks were used to produce particleboard with UF resin. The effects of liquid hot water pretreatment temperature and residence time on the wax contents and pH values were investigated. In addition, the buffering capacities of the rice husks and the mechanical properties and the water resistance of the rice husk particleboards were investigated. The results indicated that liquid hot water pretreatment remarkably reduced the wax contents, pH values, and buffering capacities of the rice husks. In addition, it improved the mechanical properties and water resistance of the rice husk particleboards. Liquid hot water pretreatment effectively improved bondability between rice husks and water-borne UF resin, and it enhanced the performance of the rice husk particleboard.
Effect of infill value on decay resistance, thermal, and mechanical properties of 3D printed polylactic acid composites filled with wood fibers
Authors: Sun Yufeng , Lee Danbee , Wang Yapeng , Li Suiliang , Ying Jilai , Liu Xinping , Xu Guangyin , Gwon Jaegyoung , Wu Qinglin
Published: July 2021

Polylactic acid (PLA)-based composites with wood filler were 3D-printed using fused deposition modeling (FDM) at different infill settings (i.e., 10 to 100%) to evaluate their strength and biodegradation properties. Microvoids were present in the commercial wood-filled PLA filaments. Wood-PLA filament had reduced thermal stability compared with mineral-filled PLA filament due to the presence of thermally degradable wood flour. The printed composites had a denser internal structure with increased infill. The flexural modulus of elasticity and modulus of rupture also increased with infill value. Sixteen-week fungi test performed using a brown rot, Postia placenta, and a white rot, Irpex lacteus, did not lead to significant sample weight loss and strength reduction for composites at various infill values. Therefore, 3D printed composites with PLA-based filament containing 30 wt.% wood fiber were shown to be resistant to biodegradation by common decay fungi.
Towards a source-oriented approach to typological universals
Authors: Cristofaro Sonia
Published: July 2021

Typological universals are skewed distributional patterns whereby languages recurrently display certain grammatical patterns as opposed to others. Explanations for these patterns are usually based on their synchronic properties, not actual diachronic processes that shape the pattern cross-linguistically. The paper discusses diachronic evidence about the origins of some typological universals pertaining to word order and aspect/tense conditioned alignment splits. This evidence poses two general challenges for synchronically based explanations of typological universals. First, the relevant patterns do not obviously arise because of the principles postulated to account for these patterns on synchronic grounds. Second, the development of these patterns is a combined result of multiple diachronic processes. These facts point to a new, source-oriented approach to typological universals, one focusing on what source constructions and developmental mechanisms play a role in the shaping of individual patterns, rather than the synchronic properties of the pattern in itself.
The Cutting Edge of Atrial Fibrillation Ablation
Authors: Verma Maya S , Terricabras Maria , Verma Atul
Published: July 2021

This article describes the advances in catheter ablation for AF that have allowed the creation of more durable and efficient lesions. It describes advances in high-power, short-duration radiofrequency ablation, radiofrequency balloon devices, ultra-low cryoablation and irreversible electroporation. It also considers the way these devices may change the way catheter ablation is performed for AF.
Reconceptualising Atrial Fibrillation Using Renewal Theory: A Novel Approach to the Assessment of Atrial Fibrillation Dynamics
Authors: Quah Jing Xian , Dharmaprani Dhani , Lahiri Anandaroop , Tiver Kathryn , Ganesan Anand N
Published: July 2021

Despite a century of research, the mechanisms of AF remain unresolved. A universal motif within AF research has been unstable re-entry, but this remains poorly characterised, with competing key conceptual paradigms of multiple wavelets and more driving rotors. Understanding the mechanisms of AF is clinically relevant, especially with regard to treatment and ablation of the more persistent forms of AF. Here, the authors outline the surprising but reproducible finding that unstable re-entrant circuits are born and destroyed at quasi-stationary rates, a finding based on a branch of mathematics known as renewal theory. Renewal theory may be a way to potentially unify the multiple wavelet and rotor theories. The renewal rate constants are potentially attractive because they are temporally stable parameters of a defined probability distribution (the exponential distribution) and can be estimated with precision and accuracy due to the principles of renewal theory. In this perspective review, this new representational architecture for AF is explained and placed into context, and the clinical and mechanistic implications are discussed.
On the occurrence of Persian Gulf Sea Snake, Hydrophis lapemoides (Gray, 1849) (Reptilia, Squamata, Elapidae, Hydrophiinae), along the coast of Bangladesh
Authors: Chowdhury Mohammad Abdul Wahed , Islam Md. Rafiqul , Auawal Abdul , Hasan Najmul , Uddin Harij , Haidar Ibrahim Khalil Al
Published: July 2021

We provide the first evidence of the presence of the Persian Gulf Sea Snake, Hydrophis lapemoides (Gray, 1849), along the coast of Bangladesh. This species was assumed to exist in there, but neither specimens nor confirmed observations exist until now. We document here the first confirmed record of H. lapemoides based on a freshly collected and taxonomically verified specimen from coastal Bangladesh. The Bangladeshi specimen had the following diagnostic characters: 55 black bands, a dorsal scale composition of 35:51:43, 342 ventrals, one pre-ocular, two post-oculars, 2+3 temporals, 8 supralabials (II largest and contact prefrontals; III–IV contact orbit) and 8 infralabials (I–IV contact genials).
Teaching and learning how to make requests in different contexts in Italian as a foreign language
Authors: Mendes Porcellato Adriana
Published: July 2021

This study is motivated by the dearth of research in pragmatic instruction in Italian as a foreign language (IFL) with beginner learners. Based on the limitations in the way IFL textbooks present requests, instructional material was designed with the following objectives: to improve learners’ pragmalinguistic and sociopragmatic competences and to raise their awareness of request realisation across different contexts. The material, designed for a 60-minute pedagogical intervention, was then used in an Italian language school in Sao Paulo with five intact classes of beginner Brazilian learners of Italian. We implemented a pre- and post-test quasi-experimental methodological design, where three classes were randomly selected to serve as the experimental group, and two classes served as the control group. The data collected through written DCTs and simplified retrospective questionnaires revealed that the learners in the experimental group showed a more significant improvement in their socio pragmatic, pragmalinguistic and metapragmatic competence compared to the control group. These results suggest a positive effect of consciousness-raising activities on learners’ declarative knowledge in the short term.
Standards and practices for reporting plankton and other particle observations from images
Authors: Neeley Aimee , Beaulieu Stace E. , Proctor Chris , Cetinić Ivona , Futrelle Joe , Soto Ramos Inia , Sosik Heidi M. , Devred Emmanuel , Karp-Boss Lee , Picheral Marc , Poulton Nicole , Roesler Collin S. , Shepherd Adam
Published: July 2021

This technical manual guides the user through the process of creating a data table for the submission of taxonomic and morphological information for plankton and other particles from images to a repository. Guidance is provided to produce documentation that should accompany the submission of plankton and other particle data to a repository, describes data collection and processing techniques, and outlines the creation of a data file. Field names include scientificName that represents the lowest level taxonomic classification (e.g., genus if not certain of species, family if not certain of genus) and scientificNameID, the unique identifier from a reference database such as the World Register of Marine Species or AlgaeBase. The data table described here includes the field names associatedMedia, scientificName/ scientificNameID for both automated and manual identification, biovolume, area_cross_section, length_representation and width_representation. Additional steps that instruct the user on how to format their data for a submission to the Ocean Biodiversity Information System (OBIS) are also included. Examples of documentation and data files are provided for the user to follow. The documentation requirements and data table format are approved by both NASA’s SeaWiFS Bio-optical Archive and Storage System (SeaBASS) and the National Science Foundation’s Biological and Chemical Oceanography Data Management Office (BCO-DMO).
A BRIEF SURVEY ON DYNAMIC NETWORK FLOWS IN CONTINUOUS-TIME MODEL
Authors: Prasad Pangeni Badri , Nath Dhamala Tanka
Published: July 2021

In dynamic network flows, when some commodities move from one place to another, time taken by them to traverse the path are taken into account, unlike the static flows. Time being continuous entity, network flow problems are modeled in its continuous setting to get more realistic solution
to the optimization problems. Rather, it can also be discretized to get more computational results. In this paper, insight is given to the models formulated by the researchers in dynamic network flows along with some practical applications regarding the triple optimization problem in continuous
time setting mainly focusing on cost minimization problems, since the quickest path problem and the maximum flow problem are considered as two important special cases of the minimum cost flow problem. Different solution strategies and their efficiencies carried out by them are also observed.
Further possible modification in the existing formulations and algorithms for better solution of problems are suggested as research endeavor.
Post Covid-19 Bio-Imaging: Cancer Detection & Secured Procurement through Dual Neurons Genetic Key (DNGK) in Advanced Medical Sciences
Authors: Dey Joydeep , Mukherjee Soumi , Sarkar Arindam , Karforma Sunil
Published: July 2021

Cancer is one of the highly-rated causes that lead to human mortality. Nowadays with the greater affect of the COVID-19 pandemic, co-morbid patients are at the dual risk of death. Therefore, the main aim of this paper is the specific detection of the cancer cells using nanoparticles further, report analysis using Artificial intelligence, and then the transmission of the medical report is to be done in a neural secured procurement. A simple mechanism to detect cancerous cells through Artificial Neural Networks (ANN) has been proposed here. Moreover, secure attainment of the patients’ medical data has been shown here with the help of Dual Neurons Genetic Key (DNGK). Structural and functionally equivalent ANNs have been iterated to generate the DNGK. In addition, genetic operations were included to make the session key more secured from the opponents. Nanoparticles are frequently used for specific cancer detection on the human body. A revolution in the form of telemedicine in the advanced medical sciences has emerged with the cameo of novel coronavirus things (IoT). It has helped to curtail the coronavirus chain through remote treatments. An Artificial Neural Network will be trained to detect the cancerous cells of the human body. The decision generated by ANN would be encrypted through the AES algorithm and DHNK before procured to the network. The Artificial Neural Network had been trained on different bio-images so that it generates an automated decision. Thus, prompt, safe, and automated cancer detection may be done using this proposed technique. Results derived from different tests on the proposed technique were evaluated and thus, validating the entire proposed technique. Thus, loads of societal development would happen in the fields of Medical Sciences, especially during these post-COVID-19 crisis hours.
COMPARATIVE STUDY OF FUZZY MATHEMATICS AS FUZZY SETS AND FUZZY LOGICS
Authors: Dixit Sonal , Verma Kirti
Published: July 2021

Fuzzy mathematics is considered to be an important aspect in the field of mathematics that interprets the uncertainties and deals with the unreliable information and vagueness of data. In this chapter we shall discuss the concept of fuzzy mathematics as fuzzy set and fuzzy logics and
the beginning of fuzzy set theory and the fuzzy logics with their applications in the real life. As fuzzy mathematics and fuzzy logics are becoming increasingly significant as it is applied in almost every field of developments, engineering design and models and in new technologies also. We
also discuss some recent models of fuzzy logics given by T. Patro[8] and C.K. Muthumaniraj [2] Fuzzy logics are playing very important role in many areas. I tried to make this chapter as a strong base for researchers and students so that it can prove strong base for further researches for
comparative study of fuzzy set theory and fuzzy logics.
Telecardiological COVID-19 (2nd) Wave: Metaheuristic-Key Guides Protected Encryption of Heterogeneous Cardiac Reports
Authors: Dey Joydeep
Published: July 2021

The epic COVID-19 had pushed the clinical sciences for another new allied branch as telemedicine services. In the field of COVID-19 (2nd) wave telemedicine, Internet and nature propelled algorithms helped to impart private data of various cardiovascular reports to various cardiologists for better treatment, perspectives, and opinion. Such heterogeneous cardiovascular reports are to be gotten so as to re-establish the patients’ protection. Metaheuristic-key has been proposed through metaheuristics calculation followed by the standard AES 128 bits encryption. Cardiovascular infections (CVDs) are heart sickness identified with blockage of arteries and veins. Heart co-morbid patients are at the most elevated danger of COVID-19. Such patients are to be analyzed and treated appropriately within the restrictions of lockdown. This paper presents a got protected directing of the heterogeneous cardiovascular reports of the patients. Such were to be applied on the proposed metaheuristic-key followed by AES encryption. Making the heterogeneous reports into non-meaningful organization for the gatecrashers is the vital target of the proposed method. A few numerical tests were carried on the proposed strategy, and getting worthy outcomes. To translate the proposed metaheuristic-key through quickest figuring computing framework, the measure of time required has been calculated as8.5× 1052years. Along with these fine lines, pushing the COVID-19 telecardiology framework with more got and remarkable credits on the society.
APPLYING A NEW HYBRID APPROACH TO PROVIDE EXACT SOLUTIONS FOR PARTIAL INTEGRO-DIFFERENTIAL EQUATIONS
Authors: Toma George Albert , Alturky Shaza
Published: July 2021

This paper suggests a new hybrid strategy for partial integro-differential equations arising in engineering applications. The new proposed method is based on hybridization the Kharrat-Toma integral transform with the homotopy perturbation method. This hybrid scheme aims to obtain exact solutions to several partial integro-differential equations subject to boundary or initial conditions in an effective and elegant compared to the numerical and analytical methods. In addition, that it reduces the integrals and computational steps. The obtained results display the applicability of the new suggested technique.
A REVIEW ON HYPER-PARAMETER OPTIMISATION BY DEEP LEARNING EXPERIMENTS
Authors: Bhattacharjee Rohan , Ghosh Debjyoti , Mazumder Abhirup
Published: July 2021

It has been found that during the runtime of a deep learning experiment, the intermediate resultant values get removed while the processes carry forward. This removal of data forces the interim experiment to roll back to a certain initial point after which the hyper-parameters or results
become difficult to obtain (mostly for a vast set of experimental data). Hyper-parameters are the various constraints/measures that a learning model requires to generalise distinct data patterns and control the learning process. A proper choice and optimization of these hyper-parameters must
be made so that the learning model is capable of resolving the given machine learning problem and during training, a specific performance objective for an algorithm on a dataset is optimised. This review paper aims at presenting a Parameter Optimisation for Learning (POL) model highlighting
the all-round features of a deep learning experiment via an application-based programming interface (API). This provides the means of stocking, recovering and examining parameters settings and intermediate values. To ease the process of optimisation of hyper-parameters further, the model involves
the application of optimisation functions, analysis and data management. Moreover, the prescribed model boasts of a higher interactive aspect and is circulating across a number of machine learning experts, aiding further utility in data management.
Contribuições da comunicação alternativa no desenvolvimento da comunicação de criança com transtorno do espectro do autismo
Authors: Montenegro Ana Cristina de Albuquerque , Leite Gabrielle Araújo , Franco Natália de Melo , Santos Debora dos , Pereira Jakciane Eduarda Araújo , Xavier Ivana Arrais de Lavor Navarro
Published: July 2021

RESUMO Este artigo apresenta as contribuições do uso de um sistema de Comunicação Aumentativa e Alternativa de alta tecnologia no desenvolvimento das habilidades comunicacionais de uma criança com Transtorno do Espectro do Autismo (TEA). Para isso, foi realizado um estudo de caso com uma criança de 2 anos e 2 meses, durante 24 sessões de terapia, ao longo de oito meses. Como instrumentos de avaliação, foram utilizados o Autism Treatment Evaluation Checklist e o protocolo Avaliação da Comunicação no Transtorno do Espectro do Autismo. Durante as intervenções, utilizou-se o método Desenvolvimento das Habilidades Comunicacionais no Autismo e, como recurso de Comunicação Aumentativa e Alternativa, a prancha de alta tecnologia do aplicativo aBoard. De acordo com os resultados, após as intervenções foram observadas melhoras nos escores dos instrumentos de avaliação, quanto às habilidades de expressão, compreensão e interação social. Além disso, observou-se aumento do vocabulário da criança, com aquisição de novas categorias lexicais; realização de solicitações de objetos fora do alcance visual, utilizando a Comunicação Aumentativa e Alternativa, e melhor comunicação social no contexto familiar e educacional. De acordo com os resultados obtidos, puderam ser observadas as contribuições do uso de um sistema de alta tecnologia assistiva de Comunicação Aumentativa e Alternativa no desenvolvimento das habilidades comunicacionais de uma criança com TEA.
Fatiga por compasión y agotamiento profesional en personal de salud ante el duelo y muerte en contextos hospitalarios
Authors: Córdoba-Rojas Diana Norella , Sanz-Guerrero Daniela , Medina-Ch Ana María , Buitrago-Echeverri María Teresa , Sierra-González Ángela María
Published: July 2021

Resumen Este artículo pretende identificar y analizar en la literatura la producción relacionada con la fatiga por compasión y el agotamiento psicológico presente en el personal sanitario que brinda atención y cuidado a personas durante los procesos de muerte y duelo de pacientes y sus familiares, respectivamente. Esta es una revisión integradora en las bases de datos JSTOR, ProQuest, Medline (vía PubMed), LILACS y Google Scholar en el periodo 2005-2018. La revisión permitió la identificación de tres cuerpos importantes de producción académica: trabajos de corte cualitativo que describen el fenómeno; los que desarrollan escalas y herramientas de medición del problema; y los que describen estrategias desarrolladas frente al mismo. En los contextos hospitalarios al personal de salud que acompaña a persona durante el proceso de muerte se le impide demostrar sentimientos y vivir el duelo por la pérdida de sus pacientes. Los trámites administrativos, la despersonalización sanitaria, el número de pacientes a cargo y la baja conciencia en relación con la muerte regulan de cierta forma lo acontecido, impidiendo que exista por parte del personal de salud descarga de sentimientos, llevándolos a presentar agotamiento psicológico y fatiga por compasión.
Significados do uso de plantas medicinais para docentes do curso de enfermagem na Catalunha
Authors: Badke Marcio Rossato , Cogo Silvana Bastos , Sehnem Graciela Dutra , Monteiro Amanda Suélen , Scopel Mariana Ferreira , Martorell-Poveda Maria-Antonia
Published: July 2021

Resumo O objetivo deste trabalho é conhecer os significados que o uso de plantas medicinais como terapia complementar no cuidado à saúde tem para docentes do curso de enfermagem na Catalunha. Trata-se de uma pesquisa qualitativa, do tipo exploratória e descritiva, realizada por meio de entrevista semiestruturada com quatro docentes do curso de enfermagem de uma universidade espanhola situada na região da Catalunha, no mês de maio de 2016. Para interpretação dos dados foi utilizada a análise de conteúdo proposta por Bardin. Na análise de conteúdo, emergiram dois temas: conhecimento e utilização de terapias complementares; e a cultura familiar influenciando o uso das plantas medicinais. Na primeira categoria, destacou-se que, além de conhecer, os professores também faziam uso das plantas frequentemente. Na segunda, ressalta-se como a influência familiar esteve presente e foi importante para perpetuar o conhecimento e formas de utilização durante as gerações. Evidenciou-se a popularização das terapias complementares e, portanto, é indispensável a articulação da prática pelos profissionais de saúde desde o processo de formação, sobretudo na enfermagem, tendo em vista a integralidade do cuidado oferecido ao usuário.
2020 NAS TELAS: ESCOLA ONLINE PARA CRIANÇAS EM FASE DE ALFABETIZAÇÃO
Authors: Tonin Juliana , Machado Anderson dos Santos , Dias Patrícia Ruas
Published: July 2021

Este artigo pretende compartilhar pesquisa sobre a adaptação da escola às telas no cenário pandêmico de 2020 para promover reflexões sobre educação online para crianças em fase de alfabetização. Através de pesquisa-ação realizada pelo LabGim (Laboratório de Pesquisas da Comunicação nas Infâncias), acompanhou-se a experiência de uma escola privada de Porto Alegre, com crianças em fase de alfabetização, no período de 26 de março a 15 de maio de 2020, sobre a qual pretende-se apresentar as análises deste cenário. Com ênfase na identificação de duas problematizações (I e II) acerca da mediação por tecnologias digitais de informação e comunicação (TDICs) na reestruturação das estratégias de continuidade das aulas, foram realizadas coletas e análises de dados em três diferentes dimensões comunicacionais (emissor, mensagem e receptor), todas elas servindo de base para a ação exercida diretamente com a equipe pedagógica da escola. Como resultado principal, identificamos três temporadas distintas na adaptação da escola e das crianças naquele período (Primeira Temporada PT, Temporada de Transição TT e Segunda Temporada ST), evidenciando as condições essenciais da educação online para crianças desta faixa etária e deste ano escolar pela possibilidade de configuração de estratégias comunicacionais de mediação online promotoras de experiências de estar junto virtual.
Intelligence in Strategic Games
Authors: Naumov Pavel , Yuan Yuan
Published: July 2021

If an agent, or a coalition of agents, has a strategy, knows that she has a strategy, and knows what the strategy is, then she has a know-how strategy. Several modal logics of coalition power for know-how strategies have been studied before.

The contribution of the article is three-fold. First, it proposes a new class of know-how strategies that depend on the intelligence information about the opponents’ actions. Second, it shows that the coalition power modality for the proposed new class of strategies cannot be expressed through the standard know-how modality. Third, it gives a sound and complete logical system that describes the interplay between the coalition power modality with intelligence and the distributed knowledge modality in games with imperfect information.
Method for predicting factor of safety and seepage due to variation in dam width and other parameters
Authors: Khan Muhammad Israr , Wang Shuhong
Published: July 2021

Slope stability analysis and seepage analysis are two important aspects of embankment stability. Landslides are a common risk faced by many people in the world, with this risk increased in the case of an earthfill embankment or water reservoir. People living in downstream regions are always at risk if the dam is not designed to achieve full strength. In this work, a pre-defined earthfill dam was analysed to assess its strength with variations of dam width (WD), shear strength of the soil (τ) and dam slope angle (β). The factor of safety was considered as the dependent, with WD, τ and β as independent variables. A pre-defined proposed dam model was analysed using limit equilibrium (LE) methods with the help of the LE software Slide. Linear regression analysis was performed using SPSS (Statistical Package for Social Sciences) software and equations were developed. The computed equations show a very close relation of all the analysed parameters. The coefficient of determination (R2) of all the developed correlations was found to be very high and the equations can thus be used in design analysis of slopes, embankments and earthfill dams.
‘Test, Test, Test!’: Scarcity, Tinkering, and Testing Policy Early in the COVID-19 Epidemic in France
Authors: Beaudevin Claire , Berlivet Luc , Boudia Soraya , Bourgain Catherine , Cassier Maurice , Gaudillière Jean-Paul , Löwy Ilana
Published: July 2021

This article follows the introduction of COVID-19 polymerase chain reaction (PCR) diagnostic tests in France. It shows how, at the intersection of science, medicine, politics, and policy-making, the test, trace, and isolate (TTI) strategy played out during the first months of the pandemic against a backcloth of multiple shortages. In so doing, the authors move beyond trite explanations (such as ‘French public health’s backwardness’) to highlight how successive policy inflections affected the national response to the pandemic. The piece analyses the shifting French political discourse surrounding (scarce) COVID-19 tests while exploring ad-hoc regulations and guidelines as well as the intense ‘bricolage’ that they triggered in the field of clinical medicine. The authors contend that the limitations of the testing infrastructure in France during the first half of 2020 shaped the decision to resort to lockdown. The research article sheds light on two coexisting registers of professional uses of reverse transcription-polymerase chain reaction (RT-PCR) assays—a ‘public health use’ and a ‘clinical use’—and highlights the changing political and social relevance of these two registers, with scarcity as a major determinant of these changes. One of the striking aspects of the introduction of COVID-19 tests in France therefore lies in the enduring gap between the dynamics of the epidemic and the dynamics of testing. In this respect, the French situation is neither extreme nor unique, which makes this case study a relevant basis for the international comparison of testing practices in different phases of the COVID-19 pandemic.
Anti-plaque efficacy of a novel Moringa oleifera dentifrice v1
Authors: Varma Sudhir
Published: July 2021

Objectives: The use of herbal dentifrices has grown exponentially over the years. They are categorically referred to as ethnomedicines. Various agents have been tried with contradicting findings based on phytopharmacological analysis. Miswak is one agent which has been used over the years. A novel Moringa Oleifera based dentifrice has given promising results in terms of its cytotoxicity, biocompatibility, and as a potent anti-inflammatory agent.Therefore, the present study aims to compare the efficacy of two commercially available Miswak and Moringa based herbal dentifrices on the reduction of plaque and gingivitis scores. Materials and Methods: This randomized clinical cross-over study included 20 subjects with mild to moderate gingivitis. The study was conducted over a total examination period of 20 days with a wash-out period of 2 weeks between the use of both the toothpastes. The Plaque index and Gingival index of the study subjects were recorded at the designated time intervals throughout the study period. Statistical Analysis: The data collected was entered on Microsoft Excel, and statistical analysis using SPSS software (SPSS version 28, Armonk, NY, IBM Corp, USA) was done. The statistical test used was the Wilcoxon sign rank test.Moreover, the P<=0.05 was considered significant. Results: The results showed that the reduction in mean gingival index scores from baseline to day 3 was more statistically significant in Moringa based dentifrice. Similarly, the plaque index scores showed statistically significant reduction following the use of Moringa based dentifrice when compared to Miswak dentifrice. This study reveals that Moringa dentifrice is a safe and effective agent in reducing plaque accumulation and treating gingival inflammation. Conclusion: The current study aims to provide an insight into the possible role of Moringa dentifrice as a possible adjunctive oral hygiene aid
Keller's Band Counting Method with Chloroquine v1
Authors: Rüdiger Salima
Published: July 2021

Supercoiling plays a major role in the regulation of bacterial growth, especially in the circadian rhythm of cyanobacteria. The Keller's Band Counting Method was modified with the use of intercalating substance chloroquine (CQ), instead of using ethidium bromide (EthBr). The principle of that method is to conserve supercoils through intercalation and unwinding of not intercalated supercoils through Topoisomerase I. Using different concentrations of the intercalating substance cause different levels of supercoiling. The treated samples were applied on agarose gels containing different concentrations of intercalation substance as well. This method allows counting all topoisomers from native, to completely relaxed state. So, the full extent of supercoiling is defined exactly. The modified method can be adapted easily, to establish correct conditions to monitor the in vivo supercoiling of other, biotechnologically relevant plasmids (expression vectors of reporter genes or heterologous expression).
La censura de Félix Restrepo al título de La mala hora: una contienda glotopolítica entre el fascismo y la letra
Authors: Chaves Carolina
Published: July 2021

Este artículo examina la autoridad lingüística del reverendo Félix Restrepo durante el siglo xx colombiano y la influencia del franquismo, a través del ejercicio de censura del Instituto Nacional del Libro Español (inle), en la literatura colombiana del siglo xx. Concretamente, el texto recoge un episodio de intervención lingüística en el campo literario colombiano, relacionado con el cambio de nombre de la novela La mala hora de García Márquez en 1962. El campo de reflexión es el de la sociolingüística crítica con perspectiva glotopolítica, que precisa la atención a las relaciones de poder y dominio ancladas en el contexto político específico en el que se produce la disputa lingüística.
Subversión del paradigma narco en El ruido de las cosas al caer de Juan Gabriel Vásquez
Authors: Jastrzębska Adriana Sara
Published: July 2021

El artículo propone una lectura de la novela El ruido de las cosas al caer (2011), de Juan Gabriel Vásquez, desde la perspectiva de la llamada convención y poética narco existente en la narrativa colombiana. El objetivo del trabajo es demostrar una paradójica condición de la obra analizada: manejando todos los ingredientes de dicha convención y poética narco, la novela retrata un fracaso de las ilusiones del narcotráfico como vía de ascenso social e individual, lo que la convierte en una suerte de anti-narconovela y lleva a cierta subversión del paradigma narco.
Lo que fue presente: un diario a corazón abierto
Authors: Escobar Mesa Augusto
Published: July 2021

Conferencia
Terminología y fraseología del texto técnico en alemán: características y problemas en la aplicación de la traducción automática
Authors: Castillo Bernal Maria-Pilar
Published: July 2021

El presente trabajo tiene por objeto aunar la investigación de corte lingüístico con los estudios de corpus y la posedición, de cara a construir una metodología aplicable a la traducción de textos técnicos, y a la didáctica de la misma. De manera específica, se busca profundizar y contextualizar la investigación en torno a las características del lenguaje técnico en alemán, explorar las técnicas de trasvase al es­pañol de la terminología y la fraseología especializadas en el marco de la traducción profesional y comprobar si los resultados de la traducción automática obtienen una calidad suficiente para aplicar la traducción automática en el campo de la tecnología nuclear. Para ello, se ha compilado un corpus de textos especializados y se han extraído las unidades terminológicas más frecuentes con ayuda de la he­rramienta Sketch Engine. Una vez analizadas, se someten a traducción automática para comprobar las inadecuaciones con respecto a los términos individuales, términos multipalabra y formas verbales. Los resultados muestran, por un lado, la complejidad y la variación presentes en el lenguaje de espe­cialidad de este ámbito y, por otro, que la traducción automática no alcanza una calidad suficiente para cumplir la función de las traducciones profesionales, si bien podría usarse con fines informativos. El traductor al español debe tener competencia tanto lingüística como textual y pragmática para apli­car las técnicas y estrategias necesarias para llevar a cabo una traducción funcional.
Traducción de culturemas en textos turísticos: Tratamiento en español de las voces que designan la vestimenta tradicional coreana
Authors: Robles Ávila Sara , Park Jin Seo
Published: July 2021

La vestimenta tradicional forma parte del patrimonio de una cultura y es reflejo de su idiosincrasia, su seña de identidad arraigada en la historia. En esta investigación analizamos los culturemas relativos a la indumentaria tradicional de Corea, el hanbok. Tomando como fuente la web turística institucio­nal de promoción del país asiático VisitKorea, hemos obtenido un corpus formado por un total de 18 culturemas. Para llevar a cabo el estudio hemos establecido una lista de técnicas traslativas a nivel mi­crotextual que se emplean en la traducción de estas palabras culturales para hacerlas comprensibles a hablantes de español, tratando de salvar así la enorme distancia lingüística y cultural entre ambas áreas. Nuestro interés se dirige a las unidades oracionales —no solo a las unidades léxicas—, en las cuales se reflejan distintos aspectos culturales en forma de paráfrasis o traducción explicativa. Como resultado del análisis concluimos que las técnicas que se usan con más recurrencia para traducir los culturemas de nuestro corpus son el préstamo, la descripción del aspecto y la descripción de los usuarios. A lo largo de la investigación hemos constatado que, para reducir la enorme brecha lingüístico-cultural entre Corea y los países hispanos, resulta imprescindible el dominio de las habilidades y los conoci­mientos lingüísticos e interculturales durante la labor de traducción-interpretación, más allá del puro trasvase verbal.