bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Ti Substitution on Electrochemical Performance and Evolution of LiMn1.5−x Ni0.5TixO4 (x = 0.05, 0.1, 0.3) as a High Voltage Cathode Material with a Very Long Cycle Life
Authors: Niketic Svetlana , Yim Chae-Ho , Zhou Jigang , Wang Jian , Abu-Lebdeh Yaser
Published: January 2022

The high voltage spinel material LiMn1.5Ni0.5O4 (LMNO) has the potential to increase the energy density of lithium batteries. However, its battery performance suffers from poor long-term cycling and high-temperature stability. In order to overcome these limitations, we have studied the effect of partial substitution of Mn with Ti and LiMn1.5−x Ni0.5TixO4 (x = 0.05, 0.1, 0.3), LMNTO, materials have been synthesized in a newly modified sol-gel method and then characterized by TEM, SEM (EDX), AC Electrochemical Impedance Spectroscopy and Soft X-ray Spectromicroscopy. We have demonstrated that the long-term cycling limitation with these types of materials can be resolved and herein 2000 cycles at a high C-rate have been demonstrated in half cells. We have attributed this behavior to a possible charge compensation mechanism as evidenced by a Soft X-ray Spectromicroscopy study of delithiated LMNTO materials. This work takes high energy density batteries based on high voltage spinel material one step further towards commercialization, and it is believed that further improvement can be achieved using new electrolyte formulations.
Exploring Higher-Order Conceptual Learning in an Arthropod with a Large Multisensory Processing Center
Authors: Lehmann Kenna D. S. , Shogren Fiona G. , Fallick Mariah , Watts James Colton , Schoenberg Daniel , Wiegmann Daniel D. , Bingman Verner P. , Hebets Eileen A.
Published: January 2022

Comparative cognition aims to understand the evolutionary history and current function of cognitive abilities in a variety of species with diverse natural histories. One characteristic often attributed to higher cognitive abilities is higher-order conceptual learning, such as the ability to learn concepts independent of stimuli—e.g., ‘same’ or ‘different’. Conceptual learning has been documented in honeybees and a number of vertebrates. Amblypygids, nocturnal enigmatic arachnids, are good candidates for higher-order learning because they are excellent associational learners, exceptional navigators, and they have large, highly folded mushroom bodies, which are brain regions known to be involved in learning and memory in insects. In Experiment 1, we investigate if the amblypygid Phrynus marginimaculatus can learn the concept of same with a delayed odor matching task. In Experiment 2, we test if Paraphrynus laevifrons can learn same/different with delayed tactile matching and nonmatching tasks before testing if they can transfer this learning to a novel cross-modal odor stimulus. Our data provide no evidence of conceptual learning in amblypygids, but more solid conclusions will require the use of alternative experimental designs to ensure our negative results are not simply a consequence of the designs we employed.
Myocardial Afterload Is a Key Biomechanical Regulator of Atrioventricular Myocyte Differentiation in Zebrafish
Authors: Ahuja Neha , Ostwald Paige , Gendernalik Alex , Guzzolino Elena , Pitto Letizia , Bark David , Garrity Deborah M.
Published: January 2022

Heart valve development is governed by both genetic and biomechanical inputs. Prior work has demonstrated that oscillating shear stress associated with blood flow is required for normal atrioventricular (AV) valve development. Cardiac afterload is defined as the pressure the ventricle must overcome in order to pump blood throughout the circulatory system. In human patients, conditions of high afterload can cause valve pathology. Whether high afterload adversely affects embryonic valve development remains poorly understood. Here we describe a zebrafish model exhibiting increased myocardial afterload, caused by vasopressin, a vasoconstrictive drug. We show that the application of vasopressin reliably produces an increase in afterload without directly acting on cardiac tissue in zebrafish embryos. We have found that increased afterload alters the rate of growth of the cardiac chambers and causes remodeling of cardiomyocytes. Consistent with pathology seen in patients with clinically high afterload, we see defects in both the form and the function of the valve leaflets. Our results suggest that valve defects are due to changes in atrioventricular myocyte signaling, rather than pressure directly acting on the endothelial valve leaflet cells. Cardiac afterload should therefore be considered a biomechanical factor that particularly impacts embryonic valve development.
Multispectral Imaging Using Fluorescent Properties of Indocyanine Green and Methylene Blue in Colorectal Surgery—Initial Experience
Authors: Polom Wojciech , Migaczewski Marcin , Skokowski Jaroslaw , Swierblewski Maciej , Cwalinski Tomasz , Kalinowski Leszek , Pedziwiatr Michal , Matuszewski Marcin , Polom Karol
Published: January 2022

Introduction: Image-guided surgery is becoming a new tool in colorectal surgery. Intraoperative visualisation of different structures using fluorophores helps during various steps of operations. In our report, we used two fluorophores—indocyanine green (ICG), and methylene blue (MB)—during different steps of colorectal surgery, using one camera system for two separate near-infrared wavelengths. Material and methods: Twelve patients who underwent complex open or laparoscopic colorectal surgeries were enrolled. Intravenous injections of MB and ICG at different time points were administered. Visualisation of intraoperative ureter position and fluorescent angiography for optimal anastomosis was performed. A retrospective analysis of patients treated in our departments during 2020 was performed, and data about ureter injury and anastomotic site complications were collected. Results: Intraoperative localisation of ureters with MB under fluorescent light was possible in 11 patients. The mean signal-to-background ratio was 1.58 ± 0.71. Fluorescent angiography before performing anastomosis using ICG was successful in all 12 patients, and none required a change in position of the planned colon resection for anastomosis. The median signal-to-background ratios was 1.25 (IQR: 1.22–1.89). Across both centres, iatrogenic injury of the ureter was found in 0.4% of cases, and complications associated with anastomosis was found in 5.5% of cases. Conclusions: Our study showed a substantial opportunity for using two different fluorophores in colorectal surgery, whereby the visualisation of one will not change the possible quantification analysis of the other. Using two separate dyes during one procedure may help in optimisation of the fluorescent properties of both dyes when using them for different applications. Visualisation of different structures by different fluorophores seems to be the future of image-guided surgery, and shows progress in optical technologies used in image-guided surgery.
Cortisol Awakening Reaction and Anxiety in Depressed Coronary Artery Disease Patients
Authors: Weber Cora , Fangauf Stella V. , Michal Matthias , Ronel Joram , Herrmann-Lingen Christoph , Ladwig Karl-Heinz , Beutel Manfred , Albus Christian , Söllner Wolfgang , Perschel Frank Holger , de Zwaan Martina , Fritzsche Kurt , Deter Hans-Christian
Published: January 2022

Disturbances of HPA axis functioning as represented by cortisol awakening reaction (CAR) belong to the mediating pathways linking psychosocial distress and cardiovascular risk. Both depression and anxiety have been confirmed as independent risk factors for coronary artery disease (CAD). However, data on anxiety and cortisol output in CAD patients are scarce. Based on previous data, we hypothesized that anxiety would be associated with higher cortisol output and a more pronounced morning increase in moderately depressed CAD patients. 77 patients (60 y, 79% male) underwent saliva sampling (+0, +30, +45, +60 min after awakening, midday and late-night sample). Anxiety was measured using the Hospital Anxiety and Depression Scale (HADS) and patients were grouped into anxious versus non anxious subjects based upon the recommended score (≥11). A repeated measures ANOVA yielded a significant time and quadratic time effect referring to the typical CAR. Anxious patients showed a significantly steeper 30 min increase, higher AUCi, lower waking and late-night cortisol levels. The steeper cortisol increase in the anxious group is in line with previous data and may be interpreted as a biological substrate of affect regulation. The lower basal and late-night levels coupled with greater AUCi mirror a more dynamic reactivity pattern compared to depressed subjects without anxiety.
Dermoscopy and Trichoscopy in Dermatomyositis—A Cross-Sectional Study
Authors: Żychowska Magdalena , Reich Adam
Published: January 2022

Background: (Video)dermoscopy is a non-invasive diagnostic technique that has a well-established role in dermatooncology. In recent years, this method has also been increasingly used in the assessment of inflammatory dermatoses. So far, little is known about the (video)dermoscopic features of dermatomyositis (DM). Methods: Consecutive patients with DM were included in the study and videodermoscopic assessments of the nailfolds, scalp, and active skin lesions were performed. Results: Fifteen patients with DM (10 women and 5 men) were included. Capillaroscopy showed elongated capillaries (90.9%), avascular areas (81.8%), disorganized vessel architecture (81.8%), tortuous capillaries (72.7%), dilated capillaries (72.7%), and hemorrhages (72.7%). The trichoscopic findings included linear branched vessels (80.0%), linear vessels (60.0%), linear curved vessels (53.3%), perifollicular pigmentation (40.0%), perifollicular erythema (33.3%), scaling (20.0%), white (20.0%) or yellow (20%) interfollicular scales, and white (20.0%) or pinkish (13.3%) structureless areas. Polymorphic vessels of an unspecific distribution and white or pink structureless areas were frequently observed under dermoscopy in cutaneous manifestations of DM, including Gottron’s papules and Gottron’s sign. Conclusions: Dermoscopy of the nailfolds (capillaroscopy), scalp (tricoscopy), and active cutaneous lesions may be of value in the preliminary diagnosis of DM.
Diagnostic Value of 18F-FDG PET/CT vs. Chest-Abdomen-Pelvis CT Scan in Management of Patients with Fever of Unknown Origin, Inflammation of Unknown Origin or Episodic Fever of Unknown Origin: A Comparative Multicentre Prospective Study
Authors: Ly Kim-Heang , Costedoat-Chalumeau Nathalie , Liozon Eric , Dumonteil Stéphanie , Ducroix Jean-Pierre , Sailler Laurent , Lidove Olivier , Bienvenu Boris , Decaux Olivier , Hatron Pierre-Yves , Smail Amar , Astudillo Léonardo , Morel Nathalie , Boutemy Jonathan , Perlat Antoinette , Denes Eric , Lambert Marc , Papo Thomas , Cypierre Anne , Vidal Elisabeth , Preux Pierre-Marie , Monteil Jacques , Fauchais Anne-Laure
Published: January 2022

Fluorodesoxyglucose Positron Emission Tomography (PET/CT) has never been compared to Chest-Abdomen-Pelvis CT (CAPCT) in patients with a fever of unknown origin (FUO), inflammation of unknown origin (IUO) and episodic fever of unknown origin (EFUO) through a prospective and multicentre study. In this study, we investigated the diagnostic value of PET/CT compared to CAPCT in these patients. The trial was performed between 1 May 2008 through 28 February 2013 with 7 French University Hospital centres. Patients who fulfilled the FUO, IUO or EFUO criteria were included. Diagnostic orientation (DO), diagnostic contribution (DC) and time for diagnosis of both imaging resources were evaluated. One hundred and three patients were included with 35 FUO, 35 IUO and 33 EFUO patients. PET/CT showed both a higher DO (28.2% vs. 7.8%, p < 0.001) and DC (19.4% vs. 5.8%, p < 0.001) than CAPCT and reduced the time for diagnosis in patients (3.8 vs. 17.6 months, p = 0.02). Arthralgia (OR 4.90, p = 0.0012), DO of PET/CT (OR 4.09, p = 0.016), CRP > 30 mg/L (OR 3.70, p = 0.033), and chills (OR 3.06, p = 0.0248) were associated with the achievement of a diagnosis (Se: 89.1%, Sp: 56.8%). PET/CT both orients and contributes to diagnoses at a higher rate than CAPCT, especially in patients with FUO and IUO, and reduces the time for diagnosis.
Use of a Deep Learning Approach for the Sensitive Prediction of Hepatitis B Surface Antigen Levels in Inactive Carrier Patients
Authors: Kamimura Hiroteru , Nonaka Hirofumi , Mori Masaya , Kobayashi Taichi , Setsu Toru , Kamimura Kenya , Tsuchiya Atsunori , Terai Shuji
Published: January 2022

Deep learning is a subset of machine learning that can be employed to accurately predict biological transitions. Eliminating hepatitis B surface antigens (HBsAgs) is the final therapeutic endpoint for chronic hepatitis B. Reliable predictors of the disappearance or reduction in HBsAg levels have not been established. Accurate predictions are vital to successful treatment, and corresponding efforts are ongoing worldwide. Therefore, this study aimed to identify an optimal deep learning model to predict the changes in HBsAg levels in daily clinical practice for inactive carrier patients. We identified patients whose HBsAg levels were evaluated over 10 years. The results of routine liver biochemical function tests, including serum HBsAg levels for 1, 2, 5, and 10 years, and biometric information were obtained. Data of 90 patients were included for adaptive training. The predictive models were built based on algorithms set up by SONY Neural Network Console, and their accuracy was compared using statistical analysis. Multiple regression analysis revealed a mean absolute percentage error of 58%, and deep learning revealed a mean absolute percentage error of 15%; thus, deep learning is an accurate predictive discriminant tool. This study demonstrated the potential of deep learning algorithms to predict clinical outcomes.
Medial Pedicle Pivot Point Using Preoperative Computed Tomography Morphometric Measurements for Cervical Pedicle Screw Insertion: A Novel Technique and Case Series
Authors: Kwon Ji-Won , Arreza Edward O. , Suguitan Anthony A. , Lee Soo-Bin , Sung Sahyun , Park Yung , Ha Joong-Won , Kim Tae Hyung , Moon Seong-Hwan , Lee Byung Ho
Published: January 2022

This study describes a new and safe freehand cervical pedicle screw insertion technique using preoperative computed tomography (CT) morphometric measurements as a guide and a medial pedicle pivot point (MPPP) during the procedure. This study included 271 pedicles at 216 cervical spine levels (mean: 4.75 pedicles per patient). A pedicle diameter (PD) ≥ 3.5 mm was the cut-off for pedicle screw fixation. The presence and grade of perforation were detected using postoperative CT scans, where perforations were graded as follows: 0, no perforation; 1, perforation < 0.875 mm; 2, perforation 0.875–1.75 mm; and 3, perforation > 1.75 mm. The surgical technique involved the use of an MPPP, which was the point at which the lines representing the depth of the lateral mass and total length of the pedicle intersected, deep in the lateral mass. The overall success rate was 96.3% (261/271, Grade 0 or 1 perforations). In total, 54 perforations occurred, among which 44 (81.5%) were Grade 1 and 10 (18.5%) were Grade 2. The most common perforation direction was medial (39/54, 72.2%). The freehand technique for cervical pedicle screw fixation using the MPPP may allow for a safe and accurate procedure in patients with a PD ≥3.5 mm.
Sjogren’s Syndrome: Recent Updates
Authors: Skarlis Charalampos , Raftopoulou Sylvia , Mavragani Clio P.
Published: January 2022

Primary Sjögren’s syndrome (SS) is a chronic systemic autoimmune disorder affecting primarily perimenopausal women [...]
The Role of Innate and Adaptive Immune Cells in the Pathogenesis and Development of the Inflammatory Response in Ulcerative Colitis
Authors: Kałużna Aleksandra , Olczyk Paweł , Komosińska-Vassev Katarzyna
Published: January 2022

Ulcerative colitis (UC) is a chronic inflammatory disease with an underlying excessive immune response directed against resident microbiota and/or dietary antigens. Both innate and adaptive immune cells play a crucial role in the pathogenesis of UC. In the case of innate immune response cells, neutrophils, dendritic cells, macrophages have a crucial impact on the development of the disease, as well as innate lymphoid cells, which have received a particular attention in recent years. On the other hand, mechanisms of the adaptive immune response involve cells such as: cytotoxic lymphocytes, regulatory lymphocytes Treg, or helper lymphocytes Th–Th2, Th9, Th17, Th22, among which significant discoveries about Th9 and Th17 lymphocytes have been made in recent years. Due to the presence of antibodies directed against resident microbiota or one’s own tissues, the influence of B lymphocytes on the development of UC is also highlighted. Additionally, the impact of cytokines on shaping the immune response as well as sustaining inflammation seems to be crucial. This review briefly describes the current state of knowledge about the involvement of the innate and adaptive immune systems in the pathogenesis of UC. The review is based on personal selection of literature that were retrieved by a selective search in PubMed using the terms “ulcerative colitis” and “pathogenesis of ulcerative colitis”. It included systematic reviews, meta-analyses and clinical trials. Our knowledge of the involvement of the immune system in the pathophysiology of IBD has advanced rapidly over the last two decades, leading to the development of several immune-targeted treatments with a biological source, known as biologic agents.
A Tear Metabolomic Profile Showing Increased Ornithine Decarboxylase Activity and Spermine Synthesis in Thyroid-Associated Orbitopathy
Authors: Billiet Benjamin , Chao de la Barca Juan Manuel , Ferré Marc , Muller Jeanne , Vautier Anaïs , Assad Sophie , Blanchet Odile , Tessier Lydie , Wetterwald Céline , Faure Justine , Urbanski Geoffrey , Simard Gilles , Mirebeau-Prunier Delphine , Rodien Patrice , Gohier Philippe , Reynier Pascal
Published: January 2022

About half of patients with Graves’ disease develop an orbitopathy related to an inflammatory expansion of the periorbital adipose tissue and muscles. We used a targeted metabolomic approach measuring 188 metabolites by mass spectrometry to compare the metabolic composition of tears in patients with active (n = 21) versus inactive (n = 24) thyroid-associated orbitopathy. Among the 44 metabolites accurately measured, 8 showed a significant alteration of their concentrations between the two groups. Two short-chain acylcarnitines, propionylcarnitine and butyrylcarnitine, and spermine showed increased concentrations in the tears of patients with active orbitopathy, whereas ornithine, glycine, serine, citrulline and histidine showed decreased concentrations in this group. In addition, the ratio putrescine/ornithine, representing the activity of ornithine decarboxylase, was significantly increased in patients with active compared to inactive orbitopathy (p = 0.0011, fold change 3.75). The specificity of this candidate biomarker was maintained when compared to a control group with unclassified dry eye disease. Our results suggest that the stimulation of ornithine decarboxylase by TSH receptor autoantibodies in orbital fibroblasts could lead to increased synthesis of spermine, through the increased activity of ornithine decarboxylase, that may contribute to periorbital expansion in Graves’ ophthalmopathy.
Seasonal and Long-Term Variability of Coccolithophores in the Black Sea According to Remote Sensing Data and the Results of Field Investigations
Authors: Vostokov Sergey V. , Vostokova Anastasia S. , Vazyulya Svetlana V.
Published: January 2022

Based on satellite data from the SeaWiFS, MODIS-Aqua, and MODIS-Terra scanners, the long-term dynamics of coccolithophores in the Black Sea and their large-scale heterogeneity have been studied. During the twenty years in May and June, mass development of coccolithophores population of different intensities was recorded annually. Summer blooms of coccolithophores reached peak levels in 2006, 2012, and 2017, after abnormally cold winters. It was noted that in conditions of low summer temperatures, the blooming of coccolithophores could be significantly reduced or acquire a local character (2004). In the anomalous cold summer of 2001, coccolithophore blooms was replaced by the mass growth of diatoms. Over twenty years, numerous signs of coccolithophores mass development in the cold season have been revealed. Winter blooms develop mainly in warm winters with periods of low wind activity. The formation of a thermocline and the surface layer’s stability are essential factors for initiating winter blooms of coccolithophores. It was noted that after the winter blooms of coccolithophores, their summer growth was poorly expressed. It is shown that during periods of rapid growth, the bulk of coccolithophores is concentrated in the upper mixed layer and thermocline. During the blooming period, the share of coccolithophores in phytoplankton biomass constituted 70–85%. The intensity of coccolithophore’s blooms is associated with the previous diatoms’ growth level. The effect of eddies circulation on the distribution and growth of coccolithophores is considered.
You Learn When It Hurts: Evidence in the Mutual Fund Industry
Authors: Gimeno Ruth , Sarto José Luis , Vicente Luis
Published: January 2022

This paper aims to contribute to the lack of research on the learning process of mutual fund markets. The empirical design is focused on the ability of the Spanish equity mutual fund industry to learn from its important errors. The choice of this industry is justified by both its relevance in the European mutual fund markets and some specific characteristics, such as the concentration and the banking control of the industry, which may affect the learning process. Our main objectives are to identify important trading errors in mutual fund management by applying three independent filters based on the relative importance of each decision, and then testing the evolution of these errors both at the industry level and at the fund family level. We apply the dynamic model of generalized method of moments (GMM), and we find an overall significant decrease in the percentage of important trading errors over time, thereby providing evidence of the global learning process of the industry. In addition, we find that a large number of fund families drive this evidence. Finally, we obtain that the family size and its dependence on financial groups do not seem to play significant roles in explaining the learning process. Therefore, we conclude that fund managers have incentives to learn from their important trading errors, in order to avoid them in future decisions, due to their serious negative consequences on fund performance, regardless of the characteristics of the families to which they belong.
Bankruptcy Prediction Using Machine Learning Techniques
Authors: Shetty Shekar , Musa Mohamed , Brédart Xavier
Published: January 2022

In this study, we apply several advanced machine learning techniques including extreme gradient boosting (XGBoost), support vector machine (SVM), and a deep neural network to predict bankruptcy using easily obtainable financial data of 3728 Belgian Small and Medium Enterprises (SME’s) during the period 2002–2012. Using the above-mentioned machine learning techniques, we predict bankruptcies with a global accuracy of 82–83% using only three easily obtainable financial ratios: the return on assets, the current ratio, and the solvency ratio. While the prediction accuracy is similar to several previous models in the literature, our model is very simple to implement and represents an accurate and user-friendly tool to discriminate between bankrupt and non-bankrupt firms.
Utilization of Waste Glass in Autoclaved Silica–Lime Materials
Authors: Borek Katarzyna , Czapik Przemysław
Published: January 2022

This paper aims to investigate the possibility of using waste glass of different colours as a complete substitute for quartz sand in autoclaved silica–lime samples. On the one hand, this increases the possibility of recycling waste glass; on the other hand, it allows obtaining autoclaved materials with better properties. In this research, reference samples with quartz sand (R) and white (WG), brown (BG), and green (GG) waste container glass were made. Parameters such as compressive strength, bulk density, and water absorption were examined on all samples. The samples were examined using a scanning electron microscope with an energy dispersive spectroscopy detector (SEM/EDS) and subjected to X-ray diffraction (XRD) analysis. The WG samples showed 187% higher compressive strength, BG by 159%, and GG by 134% compared to sample R. In comparison to the reference sample, volumetric density was 16.8% lower for sample WG, 13.2% lower for BG, and 7.1% lower for GG. Water absorption increased as bulk density decreased. The WG sample achieved the highest water absorption value, 15.84%. An X-ray diffraction analysis confirmed the presence of calcite, portlandite, and tobermorite phases. Depending on the silica aggregate used, there were differences in phase composition linked to compressive strength. Hydrated calcium silicates with varying crystallisation degrees were visible in the microstructure image.
Mechanical and Microstructural Anisotropy of Laser Powder Bed Fusion 316L Stainless Steel
Authors: Pitrmuc Zdeněk , Šimota Jan , Beránek Libor , Mikeš Petr , Andronov Vladislav , Sommer Jiří , Holešovský František
Published: January 2022

This paper aims at an in-depth and comprehensive analysis of mechanical and microstructural properties of AISI 316L austenitic stainless steel (W. Nr. 1.4404, CL20ES) produced by laser powder bed fusion (LPBF) additive manufacturing (AM) technology. The experiment in its first part includes an extensive study of the anisotropy of mechanical and microstructural properties in relation to the built orientation and the direction of loading, which showed significant differences in tensile properties among samples. The second part of the experiment is devoted to the influence of the process parameter focus level (FL) on mechanical properties, where a 48% increase in notched toughness was recorded when the level of laser focus was identical to the level of melting. The FL parameter is not normally considered a process parameter; however, it can be intentionally changed in the service settings of the machine or by incorrect machine repair and maintenance. Evaluation of mechanical and microstructural properties was performed using the tensile test, Charpy impact test, Brinell hardness measurement, microhardness matrix measurement, porosity analysis, scanning electron microscopy (SEM), and optical microscopy. Across the whole spectrum of samples, performed analysis confirmed the high quality of LPBF additive manufactured material, which can be compared with conventionally produced material. A very low level of porosity in the range of 0.036 to 0.103% was found. Microstructural investigation of solution annealed (1070 °C) tensile test samples showed an outstanding tendency to recrystallization, grain polygonization, annealing twins formation, and even distribution of carbides in solid solution.
Effect of Silica Fume on the Rheological Properties of Cement Paste with Ultra-Low Water Binder Ratio
Authors: He Juan , Cheng Congmi , Zhu Xiaofen , Li Xiaosen
Published: January 2022

The effect of silica fume on the rheological properties of a cement–silica fume–high range water reducer–water mixture with ultra-low water binder ratio (CSHWM) was studied. The results indicate that the W/B ratio and silica fume content have different effects on the rheological parameters, including the yield stress, plastic viscosity, and hysteresis loop area. The shear-thickening influence of CSHWM decreased with the increased silica fume content. When the silica fume content increased from 0% to 35%, the mixture with W/B ratio of 0.19 and 0.23 changed from a dilatant fluid to a Newtonian fluid, and then to a pseudoplastic fluid. When the silica fume content was less than 15%, the yield stress was close to 0. With the increase of silica fume content, the yield stress increased rapidly. The plastic viscosity and hysteresis loop area decreased slightly with the addition of a small amount of silica fume, but increased significantly with the continuous increase of silica fume. Compared with the Bingham and modified Bingham models, the Herschel–Buckley model is more applicable for this CSHWM.
Assessment of Boron Diffusivities in Nickel Borides by Two Mathematical Approaches
Authors: Keddam Mourad , Jurči Peter
Published: January 2022

In the work of this contribution, two kinetics models have been employed to assess the boron diffusivities in nickel borides in case of Inconel 718 alloy. The first approach, named the alternative diffusion model (ADM), used the modified version of mass conservation equations for a three-phase system whilst the second one employed the mean diffusion coefficient (MDC) method. The boron diffusivities in nickel borides were firstly evaluated in the interval of 1123 to 1223 K for an upper boron concentration of 11.654 wt% in Ni4B3. The boron activation energies in the three phases (Ni4B3, Ni2B and Ni3B) were secondly deduced by fitting the values of boron diffusivities with Arrhenius relations. Finally, these values of energy were compared with the results from the literature for their experimental validation.
Parametric Random Vibration Analysis of an Axially Moving Laminated Shape Memory Alloy Beam Based on Monte Carlo Simulation
Authors: Hao Ying , Gao Ming , Gong Jiajie
Published: January 2022

The study of the bifurcation, random vibration, chaotic dynamics, and control of laminated composite beams are research hotspots. In this paper, the parametric random vibration of an axially moving laminated shape memory alloy (SMA) beam was investigated. In light of the Timoshenko beam theory and taking into consideration axial motion effects and axial forces, a random dynamic equation of laminated SMA beams was deduced. The Falk’s polynomial constitutive model of SMA was used to simulate the nonlinear random dynamic behavior of the laminated beam. Additionally, the numerical of the probability density function and power spectral density curves was obtained through the Monte Carlo simulation. The results indicated that the large amplitude vibration character of the beam can be caused by random perturbation on axial velocity.
A Fuzzy Multicriteria Group Decision Making Approach for Evaluating and Selecting Fintech Projects
Authors: Wibowo Santoso , Grandhi Lakshmi , Grandhi Srimannarayana , Wells Marilyn
Published: January 2022

The use of financial technologies (Fintech) has increased recently due to their support to financial institutions in managing their financial operations and achieving competitive advantages. Even though there are several benefits with Fintech development and implementation, selecting the most suitable Fintech project can be complex. This is due to the involvement of numerous decision makers, the conflicting nature of multiple evaluation criteria, and fuzzy data derived from imprecise judgments of qualitative performance ratings. Interval-valued based intuitionistic fuzzy numbers are used to deal with the inherent vagueness and imprecision of the evaluation process. An algorithm based on an interval-valued intuitionistic fuzzy weighted geometric (IIFWG) and the concept of ideal solutions is developed. As a result, the most suitable Fintech project alternative can be selected across all evaluation criteria. To demonstrate the effectiveness of the approach, a Fintech project selection problem is presented.
Analysis of Measured Parameters in Relation to the Amount of Fibre in Lightweight Red Ceramic Waste Aggregate Concrete
Authors: Horňáková Marie , Lehner Petr
Published: January 2022

The present study provides a correlation and regression analysis of lightweight waste aggregate concretes with varying degrees of fibre reinforcement. The concrete mix contains pre-soaked red ceramic waste aggregate, expanded clay coarse aggregate and Portland cement. Copper-coated crimped steel fibre was used as the reinforcement. The experimental results included properties measured by destructive test methods—compressive strength, splitting tensile strength, static modulus of elasticity, the limit of proportionality, shear strength; and by non-destructive test methods—dynamic modulus of elasticity and surface electrical resistivity. These properties were analysed to study the relevancy and significance between non-destructive and destructive methods of measurement in the case of different amounts of fibre. The results show differences in the degree of fit to the linear and quadratic regression curves for pairs of destructive and non-destructive test results. As expected, the linear relationship can be applied in a few cases, but the quadratic curve must be used for a few pairs. Another observation is that it is not possible to neglect the amount of fibre in the correlation analyses of the measured properties.
Diffusion-Wave Type Solutions to the Second-Order Evolutionary Equation with Power Nonlinearities
Authors: Kazakov Alexander , Lempert Anna
Published: January 2022

The paper deals with a nonlinear second-order one-dimensional evolutionary equation related to applications and describes various diffusion, filtration, convection, and other processes. The particular cases of this equation are the well-known porous medium equation and its generalizations. We construct solutions that describe perturbations propagating over a zero background with a finite velocity. Such effects are known to be atypical for parabolic equations and appear as a consequence of the degeneration of the equation at the points where the desired function vanishes. Previously, we have constructed it, but here the case of power nonlinearity is considered. It allows for conducting a more detailed analysis. We prove a new theorem for the existence of solutions of this type in the class of piecewise analytical functions, which generalizes and specifies the earlier statements. We find and study exact solutions having the diffusion wave type, the construction of which is reduced to the second-order Cauchy problem for an ordinary differential equation (ODE) that inherits singularities from the original formulation. Statements that ensure the existence of global continuously differentiable solutions are proved for the Cauchy problems. The properties of the constructed solutions are studied by the methods of the qualitative theory of differential equations. Phase portraits are obtained, and quantitative estimates are determined by constructing and analyzing finite difference schemes. The most significant result is that we have shown that all the special cases for incomplete equations take place for the complete equation, and other configurations of diffusion waves do not arise.
Incidence of Emergency Peripartum Hysterectomy in a Tertiary Obstetrics Unit in Romania
Authors: Gică Nicolae , Ragea Carina , Botezatu Radu , Peltecu Gheorghe , Gică Corina , Panaitescu Anca Maria
Published: January 2022

Background and Objectives: Emergency peripartum hysterectomy (EPH) is a life-saving surgical procedure performed when medical and surgical conservative measures fail to control postpartum hemorrhage. The objective of this study was to estimate the incidence of EPH and to determine the factors leading to this procedure and the maternal outcomes. Materials and Methods: A retrospective cohort study with all cases of EPH performed at Filantropia Clinical Hospital in Bucharest between January 2012 and May 2021. Results: There were 36 EPH, from a total of 36,099 births recorded. The overall incidence of EPH was 0.99 per 1000 deliveries, most cases being related to placenta accreta spectrum disorder and uterine atony. Conclusions: Peripartum hysterectomy is associated with an important maternal morbidity rate and severe complications. Efforts should be made to reduce the number of unnecessary cesarean deliveries.
Prognosis of Subcutaneous Mastectomy for Special Types of Breast Cancer
Authors: Nakagawa Tsuyoshi , Oda Goshi , Mori Hiroki , Uemura Noriko , Onishi Iichiro , Sagawa Noriko , Fujioka Tomoyuki , Mori Mio , Kubota Kazunori , Ishikawa Toshiaki , Okamoto Kentaro , Uetake Hiroyuki
Published: January 2022

Background and objectives: In the treatment of the special type of breast cancer (STBC), the choice of chemotherapeutic agents is often based on the characteristic features of the histological type. On the other hand, the surgical strategy is usually determined by the tumor size and presence of lymph node metastasis, and the indication for immediate reconstruction is rarely discussed based on the histological type. The prognoses of STBC and invasive ductal carcinoma of the breast (IDC) patients who underwent subcutaneous mastectomy (SCM) with immediate reconstruction at our institution were compared. Materials and Methods: A total of 254 patients with SCM with immediate reconstruction from 1998 to 2018 were included; their tumor diameter or induration was less than 25 mm, and it was not in close proximity to the skin. Preoperative chemotherapy and non-invasive cancer cases were excluded. Results: The number of patients was 166 for skin-sparing mastectomy (SSM) and 88 for nipple-sparing mastectomy (NSM). The reconstructive techniques were deep inferior epigastric artery perforator flap (DIEP) reconstruction in 43 cases, latissimus dorsi flap reconstruction (LDflap) in 63 cases, tissue expander (TE) in 117 cases, and transverse rectus abdominis myocutaneous flap/vertical rectus abdominis myocutaneous flap (TRAM/VRAM) reconstruction in 31 cases. The histological types of breast cancer were 211 IDC and 43 STBC; 17 were mucinous carcinoma (MUC), 17 were invasive lobular carcinoma (ILC), 6 were apocrine carcinoma, 1 was tubular carcinoma, and 2 were invasive micropapillary carcinoma. There was no difference in local recurrence or disease-free survival (LRFS, DFS) between IDC and STBC, and overall survival (OS) was significantly longer in STBC. OS was better in the STBC group because SCM with immediate reconstruction was performed for STBC, which is a histological type with a relatively good prognosis. Highly malignant histological types, such as squamous cell carcinoma or metaplastic carcinoma, were totally absent in this study. Conclusions: The indications for SCM with immediate reconstruction for relatively common STBCs such as MUC and ILC can be the same as for IDC.
Implantoplasty Improves Clinical Parameters over a 2-Year Follow-Up: A Case Series
Authors: Martins Orlando , Sahrmann Philipp , Ramos João , Caramelo Francisco , Matos Sérgio , Baptista Isabel Poiares
Published: January 2022

Background and Objectives: Peri-implantitis treatment is still undefined. Regenerative treatment is expensive and technically demanding due to the need to handle biomaterials, membranes and different methodologies of decontamination. Resective treatment and implantoplasty might be a viable solution. This case series presents a 24 month retrospective observational study of 10 peri-implantitis patients treated with implantoplasty. Materials and Methods: In the present case series, 10 peri-implantitis patients (20 implants) were treated with a resective approach and implantoplasty. Previous to implantoplasty, all patients underwent non-surgical treatment. This surgery consisted in a full-thickness flap and implant surface exposure. The exposed non-osseointegrated implant body was submitted to implantoplasty. The flap was apically repositioned and sutured. Patients were accompanied for 24 months. Results: The mean initial probing depth (PD) (PD = 5.37 ± 0.86 mm), bleeding on probing (BoP = 0.12 ± 0.06%) and suppuration (Sup = 0.01 ± 0.01%) decreased significantly at the 12 month evaluation (PD = 2.90 ± 0.39 mm; BoP = 0.01 ± 0.01% and Sup = 0.00 ± 0.00%). Between the 12 and 24 month evaluations, there were no significant clinical changes (PD = 2.85 ± 0.45 mm; BoP = 0.01 ± 0.01% and Sup = 0.00 ± 0.00%). Mucosal recession (MR) had a significant increase between the baseline and the first 12 months (0.69 ± 0.99 mm vs. 1.96 ± 1.33 mm), but there were no significant changes between the 12th and 24th month (1.94 ± 1.48 mm). The success rate was 100% without implant fracture or loss. Conclusions: Resective surgery and implantoplasty might be a valid option in some specific peri-implantitis cases. Properly designed clinical trials are needed to confirm this possibility.
Diaphragm Ultrasound in Cardiac Surgery: State of the Art
Authors: Fayssoil Abdallah , Mansencal Nicolas , Nguyen Lee S. , Orlikowski David , Prigent Hélène , Bergounioux Jean , Annane Djillali , Lofaso Frédéric
Published: January 2022

In cardiac surgery, patients are at risk of phrenic nerve injury, which leads to diaphragm dysfunction and acute respiratory failure. Diaphragm dysfunction (DD) is relatively frequent in cardiac surgery and particularly affects patients after coronary artery bypass graft. The onset of DD affects patients’ prognosis in term of weaning from mechanical ventilation and hospital length of stay. The authors present a narrative review about diaphragm physiology, techniques used to assess diaphragm function, and the clinical application of diaphragm ultrasound in patients undergoing cardiac surgery.
Mechanical Alloying Process Applied for Obtaining a New Biodegradable Mg-xZn-Zr-Ca Alloy
Authors: Raducanu Doina , Cojocaru Vasile Danut , Nocivin Anna , Hendea Radu , Ivanescu Steliana , Stanciu Doina , Trisca-Rusu Corneliu , Drob Silviu Iulian , Cojocaru Elisabeta Mirela
Published: January 2022

The aim of the present paper is to apply the mechanical alloying process to obtain from powder components a new biodegradable Mg-based alloy powder from the system Mg-xZn-Zr-Ca, with high biomechanical and biochemical performance. Various processing parameters for mechanical alloying have been experimented with the ultimate goal to establish an efficient processing route for the production of small biodegradable parts for the medical domain. It has been observed that for the same milling parameters, the composition of the powders has influenced the powder size and shape. On the other hand, for the same composition, the highest experimented milling speed and time conduct to finer powder particles, almost round-shaped, without pores or various inclusions. The most uniform size has been obtained for the powder sample with 10 wt.%Zn. These powders were finally processed by selective laser melting, an additive manufacturing technology, to obtain a homogeneous experimental sample, without cracking, for future more systematical trials.
Experimental and Numerical Study on the Protective Behavior of Weldox 900 E Steel Plates Impacted by Blunt-Nosed Projectiles
Authors: Shi Yahui , Hu Ang , Du Taisheng , Xiao Xinke , Jia Bin
Published: January 2022

To demonstrate the importance of incorporating Lode angle into fracture criterion in predicting the penetration resistance of high-strength steel plates, ballistic tests of blunt-nosed projectiles with a diameter of 5.95 mm impacted 4 mm thick Weldox 900 E steel plates were conducted. Impacting velocity range was 136.63~381.42 m/s. The fracture behavior and the ballistic limit velocities (BLVs) were obtained by fitting the initial-residual velocities of the projectiles. Subsequently, axisymmetric finite element (FE) models parallel to the tests were built by using Abaqus/Explicit software, and the Lode-independent Johnson–Cook (JC) and the Lode-dependent ASCE fracture criterion were incorporated into the finite element model for numerical simulation. Meanwhile, to verify the sensitivity of the mesh size in the numerical simulation, different mesh sizes were used in the shear plug area of the target. It can be found that Weldox 900 E steel has obvious mesh size sensitivity by comparing the experimental results and numerical simulation, and the JC fracture criterion and the ASCE fracture criterion predicted similar BLV for the same mesh size.
Advances in Selective Flotation and Leaching Process in Metallurgy
Authors: Park Ilhwan
Published: January 2022

Metals are a finite resource that are necessary to maintain living standards in modern society, due to their countless applications, such as transportation vehicles, building and construction, household appliances, electronic devices, etc. [...]
Damage-Based Assessment of the Fatigue Crack Initiation Site in High-Strength Steel Welded Joints Treated by HFMI
Authors: Ono Yuki , Yıldırım Halid Can , Kinoshita Koji , Nussbaumer Alain
Published: January 2022

This study aimed to identify the fatigue crack initiation site of high-frequency mechanical impact (HFMI)-treated high-strength steel welded joints subjected to high peak stresses; the impact of HFMI treatment residual stress relaxation being of particular interest. First, the compressive residual stresses induced by HFMI treatment and their changes due to applied high peak stresses were quantified using advanced measurement techniques. Then, several features of crack initiation sites according to levels of applied peak stresses were identified through fracture surface observation of failed specimens. The relaxation behavior was simulated with finite element (FE) analyses incorporating the experimentally characterized residual stress field, load cycles including high peak load, improved weld geometry and non-linear material behavior. With local strain and local mean stress after relaxation, fatigue damage assessments along the surface of the HFMI groove were performed using the Smith–Watson–Topper (SWT) parameter to identify the critical location and compared with actual crack initiation sites. The obtained results demonstrate the shift of the crack initiation most prone position along the surface of the HFMI groove, resulting from a combination of stress concentration and residual stress relaxation effect.
Unlike Glycerophosphocholine or Choline Chloride, Dietary Phosphatidylcholine Does Not Increase Plasma Trimethylamine-N-Oxide Levels in Sprague-Dawley Rats
Authors: Shirouchi Bungo , Fukuda Ayano , Akasaka Taiki
Published: January 2022

Choline, betaine, and L-carnitine are transformed into trimethylamine (TMA) by gut microbiota, absorbed into the liver, and oxidized into trimethylamine-N-oxide (TMAO) by flavin-containing monooxygenases. Elevated TMAO levels may negatively affect human health. As phosphatidylcholine (PC) is the main source of dietary choline, its intake or PC-rich foods may be harmful to human health; however, quantitative comparative information among dietary choline compounds (PC, glycerophosphocholine [GPC], and choline chloride [CC]) regarding in vivo generation of TMAO is lacking. Here, we compared the effects of PC, GPC, and CC on plasma TMAO levels in rats. Furthermore, we investigated their effects on gut microbiota at the genus level. Dietary PC did not affect plasma TMAO levels, whereas dietary GPC and CC significantly increased them. At the genus level, plasma TMAO levels were significantly negatively correlated with relative abundances of Anaerotruncus, Actinomyces, Enterococcus, Dialister, Clostridium XIVa, and Granulicatella; they were significantly positively correlated with that of Coprobacter. Moreover, the relative abundances of Anaerotruncus and Coprobacter were found to predict plasma TMAO levels. Therefore, dietary PC, unlike GPC or CC, does not increase plasma TMAO levels in rats. Furthermore, several gut microbes are associated with changes in plasma TMAO levels in rats fed with choline compounds.