bluuebunny/crossref_metadata_2025 huggingface dataset:
Empoderamiento de las mujeres y la Agenda 2030: Una experiencia basada en procesos y resultados en el nordeste de Brasil
Authors: Tavares Celma
Published: March 2021

El empoderamiento de las mujeres constituye uno de los caminos para la inversión de las desigualdades de género. En este sentido, analizar experiencias que articulan el empoderamiento con los derechos humanos contribuye para indicar sus logros y lagunas y posibilitar su ampliación. Así, este texto tiene como objetivo discutir el proceso de empoderamiento de mujeres articulado a la Agenda 2030 de Naciones Unidas, tomando como referencia la experiencia desarrollada con mujeres rurales y urbanas en el nordeste de Brasil por una organización feminista, con la finalidad de reducir la desigualdad de género en el acceso, uso y control de la tierra, el territorio, la vivienda digna y la protección de la naturaleza. El estudio, fundamentado en la investigación cualitativa y en el análisis de contenido, se centró en las evidencias del proceso a partir de la relación entre los ejes de actuación y sus respectivos resultados. En líneas generales se pudo observar que el trabajo viene estableciendo las condiciones para avanzar en el empoderamiento de las mujeres en los niveles individual; de las relaciones dentro de sus movimientos de origen; y de influencia en las políticas públicas. De esa forma, se considera posible su replicación a otros territorios desde que se mantengan sus directrices y metodología, y se adecúe su desarrollo a las especificidades locales.
Dignidad humana: una mirada desde un enfoque filosófico
Authors: Samayoa Monroy Alcira Noemí
Published: March 2021

La dignidad de la persona constituye el fundamento vital de la idea de los derechos humanos, y aunque ha sido comunicado y continúa difundiéndose en nuestro tiempo, no pasa de ser un ideal en todos los países. Por lo tanto, el propósito de este artículo es reflexionar críticamente el valor de dignidad humana, desde un enfoque filosófico, ganando claridad al respecto, según el aporte de algunos pensadores como Aristóteles, Immanuel Kant, Martin Heidegger, Hannah Arendt, entre otros. Se parte de las categorizaciones pluridisciplinares y pluridimensionales, con las cuales se vincula el concepto de dignidad humana para su conformación, que nos lleva a la comprensión de este como el valor interno de la propia persona, por el hecho de serlo. Se incorporan, también, los avances notables respecto a la dignidad, con base una transición entre la edad moderna y contemporánea, como resultado de lo que el propio ser humano ha sido capaz de realizar. De tal manera, se precisa su consideración, porque actualmente la sociedad atraviesa por una decadencia de apreciación hacia la propia dignidad humana; conductas indeseables, específicamente en la sociedad guatemalteca, revelan que la persona se desvaloriza, evitando, incluso, que se le dé el honor debido como alguien individual y social.
Perspectivas en la protección no jurisdiccional del derecho humano a la vivienda en México
Authors: Venegas Agüeros Mayra Patricia , Pérez Bravo Mauro
Published: March 2021

En el presente artículo, se abordará el papel que los organismos públicos protectores de derechos humanos han realizado en lo que se refiere a la protección del derecho a la vivienda. Desde nuestro punto de vista, es necesario reforzar todos los medios que resguarden tal derecho; en este caso, hablamos de la protección no jurisdiccional realizada por los organismos mencionados. Este ensayo retoma los principales alcances y logros que han destacado en el tema, de acuerdo con los estándares constitucionales y convencionales que sean pertinentes. Lo anterior, con el propósito de que, al final, podamos hacer un balance sobre lo que implica una protección más efectiva de los derechos humanos, desde el ámbito no jurisdiccional, según los retos que implica el derecho a la vivienda para personas en situación de vulnerabilidad.
Gordofobia: existencia de un cuerpo negado. Análisis de las implicaciones subjetivas del cuerpo gordo en la sociedad moderna
Authors: Quirós Sánchez Gabriela
Published: March 2021

El presente manuscrito tiene como finalidad propiciar la reflexión en torno a la construcción social del cuerpo gordo, desde el análisis de la gordofobia como un elemento de aprendizaje psicosocial que tiene como fin la categorización de la valía personal, propiciando un posicionamiento diferenciado para las personas cuyas corporalidades no están determinadas dentro de las rígidas estructuras de la estética actual.  Los aprendizajes sobre el cuerpo tienen efectos diferenciados sobre la vida de las personas; la construcción de género, las enseñanzas sociales y la influencia de la legitimación familiar del discurso discriminatorio son algunos de los mecanismos por los que la gordofobia permea la autopercepción corporal e influye en la forma en la que nos tratamos e interactuamos con los demás. Aceptar la diversidad corporal en la región latinoamericana no solo tiene que ver con el reconocimiento de las formas de nuestros cuerpos, sino también, con la aprobación de la herencia histórica de nuestro mestizaje. Siendo esta una reivindicación pendiente que se ve asediada por la influencia de la moda, el mercado y la mirada heteropatriarcal sobre el cuerpo.
Análisis del discurso estatal ante la CIDH (OEA): Caso Venezuela
Authors: González Elienai , Buada Gabriela
Published: March 2021

El presente artículo pretende elaborar un análisis del discurso oficial en las audiencias temáticas celebradas el 27 de febrero de 2018 ante la Comisión Interamericana de Derechos Humanos (CIDH), en la ciudad de Bogotá, Colombia, en el marco del 167° período de sesiones, atinentes a los Derechos a la Alimentación y a la Salud, por un lado, y a la Asamblea Nacional Constituyente, por el otro, que a pesar de ser dos temas distintos entre sí, se considera necesario englobar en un solo trabajo ambas audiencias para reflejar la visión del Estado en su integralidad. De esta manera, mediante la revisión de los argumentos de las autoridades venezolanas, desde la perspectiva de los instrumentos legales nacionales e internacionales, así como de las fuentes institucionales y periodísticas, se develarán, de forma sistemática, los factores que han contribuido a la compleja situación actual y sus implicaciones en materia de derechos humanos.
Problems of functioning and development of a new electricity market model in Ukraine (according to the scientific report at the meeting of the Presidium of NAS of Ukraine, February 3, 2021)
Authors:   Institute of Electrodynamics of the National Academy of Sciences of Ukraine, Kyiv, Ukraine, Blinov I.V.
Published: March 2021

The most important scientific and practical results of the Institute of Electrodynamics of the National Academy of Sciences of Ukraine and other institutions of the Academy are given. The results of research are aimed at scientific and methodological substantiation of the organization and functioning of the electricity market in Ukraine, forecasting the generation of electricity from renewable energy sources, Ukrainian and European electricity market coupling to improve the efficiency of the electricity sector and Ukraine's competitiveness on European market.
Atlas “Population of Ukraine and its Natural and Cultural Heritage” (transcript of the report at the meeting of the Presidium of NAS of Ukraine, February 3, 2021)
Authors:   Institute of Geography of the National Academy of Sciences of Ukraine , Kyiv, Ukraine, Rudenko L.H.
Published: March 2021

The report deals with the development at the Institute of Geography of the NAS of Ukraine of the first in Ukraine interactive atlas “Population of Ukraine and its Natural and Cultural Heritage,” which reflects the relationship between the population and its heritage and characterizes the stages of its formation and functioning. The atlas, compiled using the methods of geographic information mapping, is a further development of conceptual solutions for the formation of thematic national infrastructure of spatial data, which was implemented during the creation of the National Atlas of Ukraine. The development can be used as a resource for information support of the planning process of balanced regional and state development in the direction of humanization of society, as well as a source of knowledge that can be useful for professionals in various specialties and for the general population.
Algebraic modeling and its application
Authors:   Glushkov Institute of cybernetics of the National Academy of Sciences of Ukraine, Kyiv, Ukraine, Letychevskyi O.О.
Published: March 2021

The article is devoted to the scientific development of the Glushkov Institute of Cybernetics of the National Academy of Sciences of Ukraine on the application of algebraic and insertional modeling technologies created on the basis of behavioral algebra. Technologies of formalization, algebraic verification, and testing of software and hardware specifications within the model-driven development method are considered. The use of algebraic modeling in biological research, development of systems based on blockchain platforms, analysis of legal and economic models is covered. One of the main areas of application of these technologies is the field of cybersecurity, which uses the method of algebraic matching and formalization of patterns of vulnerabilities and cyberattacks.
“Development of mineralogy is impossible without mineralogical meetings” — academician V.I. Vernadsky
Authors:   Ivan Franko National University of Lviv, Ukraine, Matkovskyi O.I. , Pavlyshyn V.I. ,   Semenenko Institute of geochemistry, mineralogy and ore formation of the National Academy of sciences of Ukraine, Kyiv, Ukraine, Solomatyna L.O. ,   Semenenko Institute of geochemistry, mineralogy and ore formation of the National Academy of sciences of Ukraine, Kyiv, Ukraine
Published: March 2021

The article briefly covers the history, mineral wealth, activities, problems of development of all official mineralogical museums of Ukraine that have different subordination and different status. The key role of academician V.I. Vernadsky is analyzed in the development of museums in Ukraine. Peculiarities of scientific-educational, research and scientific-organizational activity of mineralogical museums are considered.
“Jogo Tonggo” Efektivitas Kearifan Lokal; Solusi Pandemi Covid-19
Authors: Shodiq Muh Fajar
Published: March 2021

The Covid-19 pandemic has entered its 2nd year. This epidemic hit all aspects of people's lives, from the aspects of health, education, tourism, economy, social, culture, politics to 'changing' civilization. Various ways have been taken by various parties to be able to remain healthy and still be able to "live" in the midst of a pandemic that no one can be sure of when it will end. “Jogo tonggo” is one of the local wisdom-based programs launched by the Governor of Central Java, Ganjar Pranowo, which is predicted to be able to overcome various sectors, especially the economy, health and social sectors. This local wisdom of jogo tonggo has proven to be effective in helping food security, accelerating the rate of information regarding the handling and education of Covid-19, triggering human moral awareness to comply with regulations and create solidarity to protect each other and meet the needs of neighbors so as to increase the immunity of Covid-19 sufferers (OTG) and their families until the cure rate for Covid-19 patients can increase.Keywords: Jogo Tonggo; Effectiveness; Local Wisdom; Covid 19 AbstrakPandemi Covid-19 sudah memasuki awal tahun ke-2. Wabah ini memukul seluruh sendi kehidupan masyarakat, mulai segi kesehatan, pendidikan, pariwisata, ekonomi, sosial, budaya, politik sampai ‘mengubah’ peradaban. Berbagai cara ditempuh oleh berbagai pihak untuk bisa tetap eksis sehat dan tetap bisa ‘hidup’ ditengah pandemi yang tidak ada yang bisa pastikan kapan berakhir. ‘Jogo tonggo’ adalah salah satu program berbasis kearifan lokal yang dicanangkan oleh Gubernur Jawa Tengah, Ganjar Pranowo yang digadang-gadang mampu mengatasi berbagai sektor terutama ekonomi, kesehatan dan sosial. Kearifan lokal jogo tonggo ini terbukti efektif membantu ketahanan pangan, percepat laju informasi mengenai penanganan dan edukasi mengenai covid-19, memicu kesadaran moral kemanusiaan untuk taati peraturan serta timbulkan solidaritas saling menjaga dan pemenuhan kebutuhan tetangga hingga bisa meningkatkan imunitas penderita Covid-19 (maupun OTG) dan keluarganya hingga tingkat kesembuhan pasien Covid-19 bisa meningkat.Kata Kunci: Jogo Tonggo; Efektifitas; Kearifan Lokal; Covid 19
Rosuvastatin and Fenofibrate Combination in The Treatment of Mixed Hyperlipidemia: A Narrative Review
Authors: Biswas Kaushik , Tiwari Ajoy , Jadhav Prachi , Goel Amit , Chanukya G V
Published: March 2021

Introduction: Patients with mixed dyslipidemia are presented with high levels of low-density lipid cholesterol (LDL-C), triglycerides (TG), and reduced high-density lipid cholesterol (HDL-C). Though useful in lowering LDL-C, therapy with rosuvastatin is insufficient in optimizing the overall lipid profile, thus putting the patient at risk of residual cardiovascular risk. A combination of statin with other lipid-modifying agents has been used with more efficient lipid control and cardiovascular risk prevention. Of these, fenofibric acid is the most frequently used, along with rosuvastatin.

Methods: Authors conducted a literature search of published literature to assess the use of rosuvastatin and fenofibrate combination in the management of mixed hyperlipidaemia.

Results and discussion: The authors selected a total of 46 articles to be included in the review. Due to the small number of articles and heterogeneity on the combination of rosuvastatin and fenofibrate combination in mixed hyperlipidemia, the findings herein are presented using narrative summaries. Based on the thorough assessment of the selected literature, the essential themes that emerged from the review include safety and efficacy of rosuvastatin and fenofibrate combination, place of therapy of rosuvastatin, and fenofibrate combination, and potential cardiovascular risk reduction with rosuvastatin and fenofibrate combination.  

Conclusion: Based on the review, the authors suggested that the combination therapy with fenofibric acid was beneficial, well-tolerated with a similar safety profile compared with statin monotherapy. The combination therapy of moderate dose rosuvastatin and fenofibric acid led to a reduction of cardiovascular risk factors via several pathways.
Olimpíadas Brasileiras de Biologia
Authors: Oliveira Wemerson Castro , Diniz Anita Regina Kerber , Favaretto Júlia , Santos Eduarda Cristina , Alves Allynne Avylla , Oliveira Denise , Freitas Amílcar Cardoso Vilaça
Published: March 2021

No contexto das olimpíadas do conhecimento, esse artigo traz uma análise das questões das Olimpíadas Brasileiras de Biologia (OBB) realizadas entre os anos de 2007 e 2016. Foram investigados três quesitos: a área da biologia à qual se remete; com quais outras áreas do conhecimento podem ser estabelecidas relações interdisciplinares; e as competências do Ensino Médio que mobilizam. Constata-se que há uma grande variedade de áreas da Biologia, especialmente para a segunda etapa; por outro lado, as questões da primeira etapa estabelecem mais relações interdisciplinares. Geografia e Matemática se destacam como as áreas do conhecimento mais relacionadas. Com relação às competências do Ensino Médio, a mais mobilizada foi a “M6 – Entender métodos e procedimentos próprios das ciências naturais e aplicá-los a diferentes contextos”. Identificou-se, nas provas da OBB, um perfil similar à prova do ENEM, com contextualizações, relações interdisciplinares e uma abrangência de diversas competências exigidas.
Palavras-chave: Olimpíada do conhecimento; ensino de Biologia; Educação Básica.
Features of endocrinological status and fetoplacental complex in pregnant women with adenomyosis
Authors:   SI Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine, Kyiv, Skripchenko N.Y. , Pavlova O.M. ,   SI Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine, Kyiv, Mazur T.M. ,   SI Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine, Kyiv
Published: March 2021

The objective: to study the features of the endocrinological status and the fetoplacental complex in pregnant women with adenomyosis, the course of pregnancy and childbirth in these women, to develop new, systematize and improve the existing methods of diagnosis, treatment and prevention of complications and reproductive losses. Materials and methods. We examined 90 pregnant women who were divided into groups: 30 healthy women – control group, a comparison group of 30 women with adenomyosis receiving classic progesterone therapy and the main group of 30 women with adenomatosis who received advanced preserving, metabolic therapy and diet therapy. The condition of the feto-placental complex, the frequency of IUGR, hemodynamic disturbances on the part of the fetus, and the level of estriol, progesterone, cortisol, chronic gonadotropin (CGL), placental lactogen were evaluated. Results. The main complication in pregnant women with adenomyosis was placental dysfunction (the comparison group was 60.0% and the main group was 33.3%), whose structure was performed by compensated (58.2%) and subcompensated forms (35.8%). The frequency of preterm labor threat was 20.0% in comparison group and 13.3% in main one, while in the control group – 1 case, which is 3.3%. Frequency of SCR was in the comparison group – 20.0% and in the main – 3.3%. Low levels of estriol, progesterone, HHG, placental lactogen, increased cortisol levels in comparison and main groups were determined, and after treatment the indicators of the main group significantly improved. Conclusions. With timely correction of violations, prevention of fetoplacental insufficiency and complex treatment with the use of advanced classical progesterone therapy in combination with metabolic and diet therapy we can significantly reduce the frequency of various complications in pregnant women with adenomyosis. Key words: adenomyosis, pregnancy, non-pregnancy, diet therapy, metabolic therapy, preservation therapy, preventive care.
Prenatal diagnosis of Down syndrome in pregnant woman with giant uterine myoma and hereditary thrombophilia
Authors:   SI Interregional Center for Medical Genetics and Prenatal Diagnostics named after P.N. Verophotlyana DOS, Krivoi Rog, Ukraine, Veropotvelyan N.P. , Gazarova L.V. ,   SI Interregional Center for Medical Genetics and Prenatal Diagnostics named after P.N. Verophotlyana DOS, Krivoi Rog, Ukraine, Pogulyay Yu.S. ,   SI Interregional Center for Medical Genetics and Prenatal Diagnostics named after P.N. Verophotlyana DOS, Krivoi Rog, Ukraine, Savarovskaya E.S. ,   SI Interregional Center for Medical Genetics and Prenatal Diagnostics named after P.N. Verophotlyana DOS, Krivoi Rog, Ukraine, Sporish V.G. ,   SI Dnipropetrovsk Regional Clinical Hospital named after I.I. Mechnikov, Dnepr, Ukraine, Enotova N.V. ,   SI Dnipropetrovsk Regional Clinical Hospital named after I.I. Mechnikov, Dnepr, Ukraine, Finiti A.S. ,   SI Dnepropetrovsk regional pathoanatomical bureau, Dnepr, Ukraine
Published: March 2021

The article describes the case of prenatal diagnosis of Down’s syndrome in a 17 weeks of gestation fetus in a 39-year-old pregnant woman with the first detected giant necrotic uterine myoma and a tendency to hypercoagulable against the background of the heterozygous carriage of the Leyden mutation. At 20 weeks of gestation, due to the inability to proliferate through the natural birth canal, extirpation of the uterus with the fetus (without appendages) was carried out along the Rhine-Poros. At autopsy the diagnosis was confirmed. Timely medical and prophylactic measures allowed to avoid the development of thrombogenic complications. The article discusses the complications of the course of pregnancy with uterine myomas, as well as the features of the echographic pattern of degenerative changes in the myomatous nodes, indications for an operative delivery for uterine myomas, and the frequency of carriage of the Leiden mutation in the population. Key words: uterine myoma, Leyden mutation, ultrasound diagnosis,invasive prenatal diagnosis, Down’s syndrome.
Comprehensive approach to treatment of early toxicosis in pregnant after use of ART
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Kaminskiy A.V. , Kolomiichenko T.V. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Rogava I.V. ,   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine
Published: March 2021

Obstetricians-gynecologists do not always pay sufficient attention to nausea and vomiting of pregnancy (NVP), sometimes its severity is underestimated and adequate treatment is not prescribed. The objective: to investigate the efficacy and safety of the complex therapy of NVP in pregnant women after ART, including a preparation of ginger extract with pyridoxine and psychotherapy. Materials and methods. Sixty pregnant women were examined after applying VRT, with mild manifestations of NVP. The main group consisted of 30 women, with Emegest (ginger and pyridoxine extract) and psychotherapy used in NVP therapy, and a comparison group of 30 women who only adhered to recommendations on changes in diet and life. The presence of the syndrome of autonomic dysfunction was established using the A.M.Veyn questionnaire. For self-assessment of the level of reactive and personal anxiety, testing was carried out according to the method of Ch.D. Spilberger, Yu.L. Khanin. The quality of life was assessed using the SF-36 questionnaire. Results. The use of recommended NVP therapy in pregnant women after ART makes it possible to improve the condition of women already for 2–3 days, and in 2 weeks of treatment it is essential to reduce or even eliminate the symptoms of NVP. Complex therapy reduces the severity of the syndrome of autonomic dysfunction and the level of personal and situational anxiety, which, against the background of improving the overall condition, positively affects the quality of life. The applied therapy had no side effects or complications, positively influenced the further course of pregnancy and the condition of the fetus and the newborn, in particular, the frequency of preeclampsia is decreased by half and the birth asphyxia by 1.5. Conclusion. The safety and efficacy of Emegest in the complex therapy of nausea and vomiting of pregnancy allows us to recommend its use in pregnant women after ART. Key words: nausea and vomiting of pregnancy, Emegest, auxiliary reproductive technologies, psychotherapy.
Medical advantages of controlled ovarian stimulation in poor responders patients with corifolitropin-alpha and antagonists of gonadotropine-rilising-hormon s in ART clinic
Authors:   Medical Center Rodynne dzherelo, Kyiv, Ukraine, Strelko Galyna
Published: March 2021

The objective: study of the effectiveness of coriophyllotropin alpha in controlled ovarian stimulation regimens with gonadotropin-rilising hormone antagonists in poor responders. Materials and methods. The study of the effectiveness of the controlled ovarian stimulation regimen using long acting FSH in the protocol with GnRH antagonists was compared with the daily administration of recombinant FSH by the number of oocytes received, embryo digestion, pregnancy and implantation. Results. It has been shown that ovarian stimulation with the use of coriophyllotropin alfa is as effective as a daily injection of recombinant FSH for the treatment of patients with a poor response to stimulation. In addition, the perception of patients with protocols with corifolithopropin alfa results in better tolerability than traditional protocols due to fewer injections, which reduces the likelihood of early termination of treatment. Conclusion. The presented results of the study prove the effectiveness of using corifolotropin alpha in combination with additional FSH daly doses and gonadotropin-rilising hormone antagonists. The effectiveness of this regimen is comparable with standard daily FSH injections for poor responders patients. The study regimen simplify the design of the stimulation scheme, minimize the number of injections, and shorten the duration of the cycle. Key words: controlled ovarian stimulation, poor responders, coriophyllotropin alpha.
Secondary breast lymphoma. A case report
Authors:   MC Verum, Kyiv, Ukraine, Gurando A.V. , Shuliga-Nedayhlebova O.V. ,   MC Verum, Kyiv, Ukraine, Telniy V.V. ,   MC Verum, Kyiv, Ukraine, Pominchuk D.V. ,   MC Verum, Kyiv, Ukraine
Published: March 2021

In this article, in a specific clinical case, the features of the image of secondary lymphoma of the breast with the use of a multimodal clinical-radiological approach were determined and the main literature sources for increasing awareness of this rare but very important pathology are given. Radiologic features of breast lymphomas are non-pathognomonic and may mimic different forms of invasive breast cancer. However, radiologists and clinicians should be aware of this rare pathology to avoid a misinterpretation. The multimodal clinical and radiological approach can be as close as possible to the diagnosis of braest lymphoma, and will pave the way for further diagnostics as biopsy and histopathological evaluation remain the gold-standard for diagnosis. Key words: breast limphoma, digital breast tomosynthesis, full-field digital mammography, breast ultrasound, Selenia Hologic, core needle biopsy.
Screening and early diagnosis of hepatocellular carcinoma
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Kirienko V.T. , Zaytsev I. A. ,   Bogomolets National Medical University, Kyiv, Ukraine, Grushkevich V.V. ,   Main Military Medical Clinical Center, Kyiv, Ukraine, Potii V.V. ,   Donetsk National Medical University, Lyman, Ukraine
Published: March 2021

Presents the risk factors for the development of hepatocellular carcinoma, the current possibilities for screening and early diagnosis of HCC with imaging techniques, non-invasive serological markers. The categories of patients subject to HCC screening and the examination algorithm are determined. Key words: hepatocellular carcinoma, primary liver cancer, screening, early diagnosis.
Prophylaxis of obstetric and perinatal pathology at women with pathological increase of body weight during pregnancy
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Vdovichenko S.Yu. , Fakhrutdinova T.D. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
Published: March 2021

The objective: depression of obstetric and perinatal complications at pregnant women with pathological increase of body weight during pregnancy on the basis of studying of clinical-functional, endocrinologic, metabolic, morphological features of condition of fetoplacental complex and development of advanced algorithm of treatment-and-prophylactic actions. Materials and methods. We conducted examination of 264 patients who consisted on the account concerning pregnancy in female consultations of Kiev. By a method of selection of 178 women were included in retrospective research and 86 – in prospective. The main group was made by 39 pregnant women with whom led individual discussions, control – 142 women, that received traditional references in female consultation. Results. Use of the algorithm improved by us allows to improve obstetric (decrease of frequency of a preeclampsia by 12.3%; anomalies of a patrimonial deyalnost for 8.4%) and perinatal outcomes (depression of level of an asphyxia at a delivery for 9.4% and post-natal adaptation for 7.8%) deliveries of women with an excessive increase of body weight during pregnancy. Conclusion. The received results grant the right to recommend the algorithm improved by us for wide use in practical health care. Key words: obstetric and perinatal pathology, pathological increase of body weight, prophylaxis.
The oldest evolutionary mechanism by pregnancy
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Leush S.St. , Zagorodnia O.S. ,   Bogomolets National Medical University, Kyiv, Ukraine, Osadchuk S.V. ,   Bogomolets National Medical University, Kyiv, Ukraine, Demianenko A.S. ,   Perinatal Center of Kyiv, Ukraine
Published: March 2021

The article deals with the role of acid-base balance as the most evolutionarily long-standing mechanism of homeostasis regulation and its features by pregnancy. The objective: to determine the features of acid-base balance in pregnant women with vomiting in first trimester. Materials and methods. 109 pregnant women in the first and second trimester were examined, they were divided into 2 groups – 58 pregnant women in the first trimester had vomiting with different degrees of severity, and 51 pregnant women in group II had no complains in first trimester. In all subjects twice, in terms of 10–11 and 20–21 weeks, the hydrogen index, the concentration of carbonate-ion and the partial pressure of CO2 in the plasma were determined. Results. It is proved by biochemical calculations, that the statistically unlikely shift of Ph to the alkaline reaction observed with the progression of pregnancy is based on a significant difference in the absolute concentration of hydrogen ions. These changes are necessary for the adequate transport of ions through the membranes of the developing placental system. Despite the loss of electrolytes in women with early gestosis, these changes do not go beyond the limits of physiological. Conclusion. 1. Pregnant patients with vomiting during first weeks of pregnancy, despite the loss of fluid and electrolytes, maintain the stability of the acid-base balance with a slight tendency to alkalosis. 2. Pregnant women without first trimester complains do not have described moderate plasma alkalisation, whose physiological role requires further observation and research. Key words: concentration of hydrogen ions, alkalosis, vomiting in first pregnancy trimester.
An organ-preserving operation in the delivery of a pregnant woman with рlacenta preavia percreta (Clinical observation)
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Lakatosh V.P. , Bila V.V. ,   Perinatal Center of Kyiv, Ukraine, Stakhovsky A.E. ,   National Cancer Institute, Kyiv, Ukraine, Zahorodnia O.S. ,   Bogomolets National Medical University, Kyiv, Ukraine, Malanchuk O.B. ,   Perinatal Center of Kyiv, Ukraine
Published: March 2021

The article describes a clinical case of childbirth of pregnant with placenta preavia percreta, with a defeat of the bladder wall, speaking about risk factors and gestational complications. The peculiarities of diagnostics of this complication are considered, the chosen tactics of treatment (carrying out of an organ-saving operation) is discussed from the point of view of literary data. Key words: рlacenta preavia, placenta percreta.
Rock-Carved Buddhas at Ch’ilburam Hermitage in Namsan Mountain, Kyongju
Authors: Lim Young-ae
Published: March 2021

On the Namsan Mountain of Kyongju, can be found the Ch’ilburam rock-carved Buddhas. The seven Buddha and bodhisattva images are significant because of their coexistence in one space and their unique arrangement. The Ch’ilburam sculptor was inspired by the Chinese central pillar caves that the sculptor had knowledge of, and the opportunity to visit. These archetypes of the ‘central pillar cave’ layout exhibit sutra-inscribed walls. By adopting and adapting these architectural elements, Ch’ilburam replicates the primary function of the Chinese cave temple. Ultimately, the Ch’ilburam site is a compromise between the desire for a rock cave temple, and the intractable geology of Korea, which is unsuitable for these purposes. As for the production period, there is a strong case for the view that the Ch’ilburam Buddha triad and four-sided stone pillar were created simultaneously in the early eighth century.
Towards a Reassessment of Indrabhuti’s Jnanasiddhi
Authors: Gerloff Torsten , Schott Julian
Published: March 2021

This article argues for the reassessment of Indrabhuti’s Jnanasiddhi in the light of newly discovered primary witnesses and previously unnoticed relations to other works. Presumably composed in the late eighth to early ninth century CE, it belongs to the earlier phase of Tantric Buddhism, a transitional period between the predominance of the Yoga- and Mahayogatantras to the later Yoginitantras, and relates to a variety of important scriptures of this formation. While this article briefly discusses the origins, authorship, contents and context of the Jnanasiddhi, including a brief overview of its modern scholarship, it also highlights its intertextual relations with and notable influences upon other tantric works of major importance. The Jnanasiddhi stands out as a tantric scripture of paramount importance, and we attempt to demonstrate the necessity of its reassessment with recourse to hitherto neglected but nonetheless vital sources that have only recently come to light.
Thrombotic Microangiopathy Associated with Pazopanib in a Kidney Transplant Recipient
Authors: Kalla Shabana , Ellis Robert J. , Campbell Scott , Doucet Brian , Isbel Nicole , Tie Bibiana , Jegatheesan Dev
Published: March 2021

Thrombotic microangiopathy (TMA) is characterised by abnormalities in the walls of arterioles and capillaries, precipitated by hereditary or acquired characteristics, and culminating in microvascular thrombosis because of dysregulated complement activity. A number of drugs can precipitate TMA, including vascular endothelial growth factor (VEGF) inhibitors, because of their effects on endothelial repair. Pazopanib is a VEGF inhibitor used for the treatment of renal cell carcinoma (RCC); it is uncommonly associated with TMA. A 52-year-old male, 5 years post his second kidney transplant secondary to immunoglobulin (Ig) A nephropathy, presented with hypertension, fluid overload, and worsening graft function (peak creatinine 275 μmol/L, baseline 130–160 μmol/L) and nephrotic range proteinuria 2 months after commencing pazopanib for metastatic RCC. His maintenance immunosuppression included ciclosporin, mycophenolate, and prednisolone. Haematological parameters were unremarkable. Allograft biopsy demonstrated glomerular and arteriolar changes consistent with chronic active TMA, with overlying features of borderline cellular rejection. He was treated with intravenous methylprednisolone 250 mg for 3 days and commenced on irbesartan 75 mg daily. Drug-induced TMA from pazopanib was suspected, particularly given the documented association with other tyrosine kinase inhibitors (TKIs). In consultation with his medical oncologist, pazopanib was ceased, and an alternate TKI cabozantinib was commenced. Serum creatinine remained <200 μmol/L 3 months after admission. This is the first reported biopsy-proven case of TMA attributed to pazopanib in a kidney transplant recipient. With increasing clinical indications for and availability of TKIs, clinicians need to be aware of their association with TMA events in kidney transplant recipients, who are already susceptible to TMA due to abnormal vasculature, infectious triggers, ischaemia-reperfusion injury, and use of calcineurin inhibitor.
A espiritualidade nos sermões de Paul Tillich
Authors: Mendes Alex Silva
Published: March 2021

O objetivo desse artigo, é enfatizar a vida devocional de um dos mais importantes teólogos de todos os tempos. Embora Paul Tillich fosse essencialmente pensador e erudito, sua vida acadêmica jamais o afastou do púlpito. A relação de Tillich com a vida pastoral, está evidenciada em seus sermões. A vida eclesial sempre fez parte dele. A espiritualidade ocupou espaço relevante em seu dia a dia. Tillich abordava questões teológicas profundas com uma linguagem simples, como um meio prático de aproximar seus ouvintes da mensagem do evangelho.  A trajetória de Tillich como capelão, pastor e pregador, o levou a refletir sobre uma profunda espiritualidade, deixando sobressair o ser humano por traz do teólogo.
Marxismo e Libertação segundo Michael Löwy
Authors: Rocha Paulo Roberto Pedrozo
Published: March 2021

Neste texto procuramos aproximar as considerações sócio-teológicas de Michael Löwy com a militância e o fazer teológico no Brasil e América Latina nos anos 70 e 80. Busca-se ainda a reflexão sobre este momento histórico na vida teológica dos povos oprimidos e sua herança marcada nos estudos teológicos contemporâneos.
Na yaqona kei na ivakatakilakila vakavanua ena yatu Pasivika
Authors:   Te Huataki Waiora School of Health, University of Waikato, Aporosa S Apo , Gaunavou Usaia
Published: March 2021

Garibaldi and Turner (2004, p. 1, 5) explain the role that particular plants play in facilitating the shared ancestry, practices and social experience of an ethnicity. This can include spiritual connections, cultural expression and practice, ceremony, exchange, linguistic reflection, socialisation, medicinal and/or dietary systems. They term these plants ‘cultural keystone species’ and icons of identity, plants that if removed would cause some disruptions to the cultural practices and identity of an ethnic group. Undoubtedly, kava (Piper methysticum) is the cultural keystone species for many Oceanic and Pacific peoples; a “differentiating element of common culture” (Zagefka, 2016, p. 761) informing their ethno-cultural identity. That influence is also extending to new non-Pacific Island user groups who have embraced elements of kava ethno-cultural identity in what has been termed diasporic identity formation in reverse. This chapter will discuss kava with specific reference to ethnic positionality in Fiji, while recognising the tensions from inside and outside the region that support and threaten the continuance of the kava drinking tradition.
Forced Transition to Distance Learning: Students’ Expectations and Concerns
Authors:   Ural Federal University named after the first President of Russia B. N. Yeltsin, Yekaterinburg, Russian Federation, Semenova T. V. ,   National Research University Higher School of Economics,Moscow, Russian Federation, Shmeleva E. D. ,   National Research University Higher School of Economics,Moscow, Russian Federation, Daineko L. V. ,   Ural Federal University named after the first President of Russia B. N. Yeltsin, Yekaterinburg, Russian Federation, Yurasova I. I. ,   Ural Federal University named after the first President of Russia B. N. Yeltsin, Yekaterinburg, Russian Federation
Published: March 2021

Spring 2020 saw most Russian universities’ switch to distant learning due to the threat of COVID-19. The forced transition imposed new demands on faculty and students, who had to quickly adapt to the new educational conditions. These changes raised concerns about the quality of distant learning. The purpose of this study was to identify which students expressed more anxiety on expecting difficulties associated with a lack of understanding educational material under new circumstances. The study was based on the data of 6,230 Ural Federal University students polled in March 2020. Regression data analysis showed that the fear of not being able to cope with learning was more typical for the 1st and the 2nd year bachelors, for students who lowly estimate their self-regulated learning skills, for students who expected difficulties of communicating with teachers and of being motivated, as well as for students who attended classes for the sake of learning. The authors discuss possible measures to support students in the conditions of rapid and mass transition to distant learning.
University as an Intellectual Polis: Development Management in Policy Terms
Authors:   Siberian Federal University, Krasnoyarsk, Russian Federation, Efimov V. S. , Laptevа A. V. ,   Siberian Federal University, Krasnoyarsk, Russian Federation
Published: March 2021

The author considers the university existing in two modes: as an organization (a system of functional units) and as an intellectual polis (a self-governing community of active and autonomous subjects). Being an intellectual polis, the university is able to act on the frontier of science and technology, to create innovations, and to act as an institution for the development of society and human. A hypothesis is proposed: the development policy, understood as building a polis (configuring the interests and goals of various actors, forming the university community, regulating its life), is immanent for the university. It is this policy that corresponds to the complexity of the university as a system with many centers of activity and potential points of growth. The method of conceptual analysis as applied to studying the university policy reveals the following significant problems and, correspondingly, the following lines of analysis: 1) defining the subjects of university community and the conditions of their appearance; 2) structuring the political reality – explicating interests, distinguishing and solving contradictions, searching for balances, adopting political decisions, creating a «social contract»; 3) building the policy, which includes special analytics, creating a space for communication, shaping the university community, working with ideologemes, discourses, traditions, and norms; 4) implementing local policies. Of particular importance for the university is the participatory policy, which makes it possible to mobilize the activity and initiative of employees and students, and the policy of partaking, which involves partners, stakeholders, alumni in development processes. The development policy is generally aimed at changing the entire way of life and activity, the type of relations and communications within the university, i. e. at creating a favorable environment for the growth points uprise and for scientific, educational, cultural, entrepreneurial etc. initiatives and projects implementation. The paper is originally associated with applying the concept of university policy in the context of the university development problems. This work can be used in management consulting and as an element of educational programs for rectors and university management teams.
Competition among Universities: Conceptual Analysis
Authors:   Ural Federal University named after the first President of Russia B. N. Yeltsin, Yekaterinburg, Russian Federation, Sudakova E. , Sandler D. G. ,   Ural Federal University named after the first President of Russia B. N. Yeltsin, Yekaterinburg, Russian Federation, Tarasyeva T. V. ,   Ural Federal University named after the first President of Russia B. N. Yeltsin, Yekaterinburg, Russian Federation
Published: March 2021

The transition to the knowledge economy focused attention on the higher education system development and its problems, and put the universities in the situation of competition for limited resources. Free and controlled competition brings a chain of interrelated, sometimes contradictory concepts applied to higher education as a socially significant area. The authors of this research article by means of conceptual analysis aim at identifying the relationship between the concepts of «competition», «competitiveness», «efficiency», and «cooperation» regarding the higher education system. Competition and cooperation are considered to be factors which increase the efficiency of universities’ functioning. At the same time, there are contradictions in the justifications for the need to create competitive conditions for universities and in the definitions of the concept of efficiency, University is understood to be a commercial organization, its indicators being locked in its internal environment, whereas its main functions (reproduction of intellectual capital, improving the quality of human resources, orientation to the needs of the labor market) come to be out of sight. No less limited is the concept of competition, which is represented through the index of monopolization, calculated mostly through the proportion of students enrolled, beyond taking into account the peculiarities of the Russian higher education system. However, the works on competition and financing draw attention to the public good created by universities, which is not always tangible and requires the financial participation of the government. Thus, the discussions on universities’ competition and effectiveness in the context of their association with the commercial sector omit a number of socially significant elements of higher education and science.
University Efficiency Evaluation Based on Educational Production Functions
Authors:   National Research University Higher School of Economics, Moscow, Russian Federation, Egorov A. A.
Published: March 2021

his paper analyses the educational production function (EPF), which is one of the main economic instruments for the analysis of university activities. This instrument describes the relationship between university performance and amount of available resources and forms the basis for calculating efficiency scores. In this paper we present the results of Russian universities’ efficiency analysis, as well as the results of cluster analysis based on university efficiency and performance scores. The results of our analysis suggest that efficiency is a key characteristic of a university’s activity and should be considered as an important indicator for elaborating public policies in higher education together with making decisions when distributing resources among educational organizations.
The Influence of Lean Manufacturing over the Main Results of Universities’ Performance
Authors:   Kemerovo State University, Kemerovo, Russian Federation, Chelombitko A. N.
Published: March 2021

This research article assesses the implications of using lean manufacturing for universities’ educational, scientific, financial and economic activities. The research methods include comparative analysis, trend analysis, Wilcoxon T-test, Fisher’s exact test, and correlation analysis. In retrospect, when comparing data on universities that are members of the «Association of Lean Universities», there comes to be a positive effect of lean manufacturing on the indicator «Income from all sources per one scientific and educational worker» and, in less degree, on research and development work (R&D), inflation taken into account. No statistically significant relationship between lean manufacturing and the average Unified State Examination (USE) score of the students admitted to the budgetary form of education was found. A comparative analysis of lean medical schools with their «non-lean» peers showed that lean manufacturing has a positive effect on the growth of R&D, taking inflation into account. Consequently, the use of lean manufacturing allowed universities to maintain average income growth rates per one scientific and educational worker. In addition, lean universities differ from their peers in terms of R&D amount dynamics. The study is to some extent limited by lacking quantitative information on the scale of lean manufacturing implementation, as well as by the dissimilar structure of the lean universities as such, medical schools predominating among them. The research results can be useful for university management and for the lean technologies implementation partners, who are interested in making decisions on the use of lean manufacturing.
Correction to: The impact of calcite impurities in clays containing kaolinite on their reactivity in cement after calcination
Authors: Zunino Franco , Boehm-Courjault Emmanuelle , Scrivener Karen
Published: March 2021

A correction to this paper has been published: https://doi.org/10.1617/s11527-021-01654-5
Design and construction of Tintagel Castle footbridge in Cornwall, UK
Authors: Mallié Matthieu , Bols Bart , Ney Laurent , Matthews William
Published: March 2021

A dramatic new steel footbridge was completed in 2019 to improve access at the popular Tintagel Castle heritage site on clifftops in Cornwall, UK. The Anglo-Belgian design team was selected from 137 entrants in an international design competition. They describe in this paper how the unique cantilevered arch design was developed for this archaeologically sensitive site, with no direct access by road or sea and an aggressive marine environment. The two halves of the superstructure were built from 14 sections using a cable crane, leaving a symbolically important visual gap at its slender midspan. The award-winning bridge has become a tourist attraction in its own right, and the castle now has the highest visitor experience score of all of English Heritage’s 300-plus historic sites.