bluuebunny/crossref_metadata_2025 huggingface dataset:
PLANNING OF SPATIAL DEVELOPMENT IN TIMES OF WAR AND RECONSTRUCTION: A VISION FOR UKRAINE
Authors:   Institute of Geography of the National Academy of Sciences of Ukraine, Kyiv, Maruniak Eu.O. , Palekha Y.M. ,   Bilokon Ukrainian State Scientific-Research Institute of Urban Design DIPROMISTO, Kyiv, Kryshtop T.M. ,   State enterprise Ukrainian Scientific, Research and Design Institute for Civil construction (SE UKRNDPICIVILBUD)
Published: January 2023

In 2022, Ukraine became the object of full-scale russian aggression, which led to human casualties and destruction, and landscape degradation. The final consequences of the hostilities are yet to be assessed, while the need for large-scale reconstruction of the country and its regions is once again evident. In this context, a comprehensive vision of the principles of the development of territories in the post-war period is of particular relevance. The article pays attention to the framework requirements for the planning process in Ukraine and the peculiarities of the documents to be developed at the national and local levels. It has been emphasized that in view of European integration, the General Scheme of Planning of the Territory of Ukraine is the most important document which defines conceptual solutions for planning and rational use of the territory of our state, maintaining a full-fledged living environment, ensuring sustainable development, environmental protection, historical, architectural and cultural sites, determining state priorities and conditions for the development of individual regions and settlements. It should be formed as an interactive modeling system of state management that will determine the strategy for the spatial development of Ukraine as part of the European planning space. The key directions for updating the existing General Scheme have been identified. The processes of reforming urban planning documentation at the local level have been analyzed, with special attention to the proposed integrated recovery programs. The importance of further introduction into the planning process of methods related to the assessment of territories and impacts on the environment and public health has been emphasized.
A zsírszövet mint a 2-es típusú diabetest kísérő inzulinrezisztencia egyik célszerve.
Authors: Winkler Gábor , Wittmann István
Published: January 2023

Az inzulinrezisztencia az a kóros állapot, amelyben az endogén vagy a kívülről
adagolt (exogén) inzulin szöveti glükózfelvételt és -hasznosítást elősegítő
hatása elmarad az anyagcseréjüket illetően egészséges személyeken megfigyelttől.
Az egész szervezetet érinti, kitüntetett célszövetei a máj-, az izom- és a
zsírszövet, patogenetikai és az ezek hátterében álló molekuláris biológiai
folyamatai azonban részben eltérnek egymástól. Az utóbbi időben jelentősen
bővültek a zsírszövet szerepével kapcsolatos ismeretek, s egyre inkább úgy
látszik, hogy a diszfunkcionális zsírszövet a kóroki történések központi
szereplője. A kézirat áttekinti a zsírszövet szerkezetét, az adipogenezis és a
lipolízis szabályozását, a mikrobiom és a zsírszövet kapcsolatára vonatkozó
adatokat, az akut és a krónikus inzulinrezisztencia különbségeit, valamint a
zsírszöveti inzulinrezisztencia mérséklésére ma rendelkezésre álló terápiás
eszközöket. Jóllehet szelektív zsírszöveti támadáspontú, biztonságos, hosszú
távú humán alkalmazást lehetővé tevő molekula ma még nincs a reménybeli
közelségben, az első, fejlesztés alatt álló „adipeutikummal” kapcsolatos
állatkísérletes megfigyelések új kezelési lehetőség ígéretét vázolják fel. Orv
Hetil. 2023; 164(1): 3–10.
Reorienting Library Space and Services of Book Depositories under the Conditions of Martial Law in Ukraine: The Case of the Largest Libraries of Zakarpattia
Authors: MEDVED M. M.
Published: January 2023

Objective. The research aims to explore the practical experience of the activity transformation of Ukrainian libraries during the military invasion of the russian federation on the territory of Ukraine. Methods. The analysis of world publications allowed: to attempt identifying the specific methods of library work during extreme events; to conduct an analysis of the services of educational and public libraries; to prove the effectiveness of psychological and moral library support to the population; and to identify its most effective forms. Results. The substantiation of the obtained results is based on the characteristics of the library of the Uzhhorod National University and the Transcarpathian Regional Universal Scientific Library named after F. Potushniak, aimed at supporting victims of war. The most active methods of library work during the first months of the war between russia and Ukraine were revealed. Analysis of the provision of library services confirms the importance of book depositories as an important centre for uniting people for mutual support. The paper outlines practical recommendations regarding the active participation of libraries in the lives of people forced to flee from places of active hostilities. There is a burst of creative library changes associated with the reorientation of the library space and services according to the social challenge posed by russia's military aggression. Conclusions. The ability of the largest library institutions in Zakarpattia to provide moral support to people affected by the war has been revealed. The role of library support as an important factor in practical assistance to people has been confirmed.
Distance Learning as an Efficient Way to Stimulate Self-Education of Librarians of Scientific Institutions of the National Academy of Sciences of Ukraine
Authors: KLYMENKO O. Z. , SOKUR O. L.
Published: January 2023

Objective. The research is aimed at the representation of distance learning as an efficient way to stimulate self-education of librarians of scientific institutions of the National Academy of Sciences of Ukraine. Methods. The research results were obtained due to the application of a complex of general and special methods of scientific knowledge, among which the systematic and logical approach, structural-functional and information-analytical methods were decisive. Results. The library is substantiated as a conceptual component of a fundamental stabilizing society development factor in Ukraine under the conditions of global challenges of the 21st century. The work reveals functioning of the advanced training system for librarians of scientific institutions of the National Academy of Sciences of Ukraine under the quarantine. The conclusions reasoned the expediency and for the first time proposed the necessity of creating a virtual university on the basis of the V. I. Vernadskyi National Library of Ukraine.
Library Service in Ensuring the Information Ecology of an Organization: A Case Study of a Research University Library
Authors: KULYK E. V.
Published: January 2023

Objective. Information products and services provided by academic libraries to support the educational process and research are a component of the information ecology of educational institutions, but their list within each academic library depends on the institutional ecology. Therefore, it is useful to study the practical experience of various academic libraries in ensuring the information ecology of research universities. As an example, we consider the successful experience of G. Denysenko Scientific and Technical Library of the National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute" (KPI Library). Methods. A qualitative method of longitudinal research was used to obtain data and analyze the KPI Library information services. A number of primary data sources were used, such as diaries of first-hand reflection, observations, engaged in documenting and developing a narrative about the effectiveness of interaction of students, lecturers, scientists with the information environment. Analytical and review, logical, systematic methods are applied to substantiate the place of library service in information ecology. Results. The experience of KPI Library in ensuring the information ecology of the university was studied. Ways of organizing prompt, effective and safe (ecological) interaction with users and support of internal information products and services are analyzed. It is shown which services (tools and information resources) and areas of activity of the library form the information ecology of Igor Sikorsky Kyiv Polytechnic Institute. The role of the library in the formation of information culture and the culture of academic integrity of scientists, teachers and students of the university is shown. Conclusions. The considered example of KPI Library activity confirms that an academic library is directly involved in formation of the information ecology of a research university. A deeper analysis of the value of products and the effectiveness of library services for various members of the academic community as a component of the information ecology of the university may be the subject of further research.
On the Quality of Age and Sex Data in the 774 Local Government Areas of Nigeria Using the 2006 Census: Caution for the Upcoming Count
Authors: Okoro Chinonso O.
Published: January 2023

This study focuses on the quality of age and sex data in the 774 local government areas of Nigeria (except Kaura LGA, not published) using the 2006 census. The results indicate that all of the LGAs had very poor-quality age and sex data. The North-West state of Sokoto had the worst
United Nations Joint Score (96.95), while Edo State in the South-South had the least Joint Score (22.81) among the states, indicating a better quality of data. Ukwuani LGA produced the best JS of 22.79, while Abadam LGA in the NorthEast state of Borno generated the worst JS of 162.54. The
northern region of Nigeria is home to 330 (82.3%) of the 401 LGAs classified as grossly inaccurate based on the Joint Scores. Similarly, 50 out of the 60 LGAs with a UN JS above 100 are in the Northern Region. The notion that the Northern Region of Nigeria is larger than the Southern Region
in population size may be a product of massive misreporting and random allocation of ages during the 2006 population census, as clearly seen in the NW and NE zones of Nigeria. Education of the populace, training and proper emoluments of enumerators and supervisors, punishment of census offenders,
and digitization of the census process are recommended in the forthcoming census in Nigeria.
The Effect of Using Manipulatives on the Performance Of Pupils in Primary School Mathematics
Authors: Muhammad Sani Mukhtar , Sani Muhammad Abdurrahman , Abdullahi Faruk , Bayaro Aliyu
Published: January 2023

This paper investigates the effects of using manipulatives on the performance of pupils in primary school mathematics. The study followed a quasi-experimental research design involving two equivalent groups: the control group and an experimental group each comprising 40 pupils. Pretest-Posttest
Mathematics Achievement Tests (PPMAT) were developed for this study. The instruments were pilot-tested and a reliability coefficient of 0.79 was obtained. The data collected were analyzed using SPSS. Teaching must be interactive, illustrative, exploratory, and student-centered. In monolingual
cultures, English becomes the progressive language of teaching in the fourth year, whereas in the first three years, education is conducted in the language of the immediate area. Children are active learners who grasp concepts by moving through three stages of knowledge: concrete, representational,
and abstract, according to the learning theory of psychologist Jean Piaget. The results of this study imply that manipulatives have positive effects on the performance of pupils in mathematics. It is recommended that manipulatives should be used as much as possible to better the mathematics
performance of pupils in primary school. This points to the fact that conceptual knowledge founded in a direct relationship of the mathematical process with necessary manipulatives is essential to build appropriate hands-on experiences to apply learning to new contexts. Students are taking
the essential first steps toward developing an understanding and internalizing mathematical processes and procedures when they manipulate objects themselves. The use of manipulatives enables pupils to explore the mathematics process at the concrete level of understanding through representational
and finally to the abstract level.
CRENÇA, VERDADE E EXATIDÃO: O REALISMO CIENTÍFICO ENCONTRA A FILOSOFIA DAS MEDIÇÕES*
Authors: Pinheiro Félix Flores
Published: January 2023

RESUMO O atual debate sobre o realismo científico é um universo inteiro. Uma tese geral pode ser assim colocada: a atividade científica alcança um mundo que é independente do próprio fazer científico. Esse “alcançar” pode ser pensado em termos de práticas teóricas, como a formulação de teorias verdadeiras, e/ou práticas experimentais, como a construção de métodos suficientemente exatos para (re)formular e testar o dito pelas teorias. Por essa última via, o debate sobre o realismo científico na filosofia da ciência encontra as discussões na filosofia das medições, uma área de pesquisa autônoma que investiga as práticas de mensuração, seus conceitos, aplicações e pressupostos. Assim como ocorre com o termo “realismo” na filosofia da ciência em geral, há múltiplas posturas caracterizáveis enquanto “realistas” por meio das teorizações sobre as medições científicas. Afirmar quais são os critérios e os motivos pelos quais essas posturas se autoproclamam realistas, bem como no que elas se distinguem, é uma tarefa complexa. Sem esgotar a discussão e o campo, este artigo consiste em uma tentativa de fazê-lo.
O uso de placas revestidas de cimentado com antibiótico é uma técnica viável e eficiente para o tratamento da pseudoartrose infectada da metáfise do fêmur e da tíbia
Authors: BIDOLEGUI FERNANDO , CODESIDO MARIANO , PEREIRA SEBASTIÁN , ABRAHAM AGUSTÍN , PIRES ROBINSON ESTEVES , GIORDANO VINCENZO
Published: January 2023

RESUMO Introdução: implantes revestidos de cimento com antibiótico vêm demonstrando bons resultados no tratamento da pseudoartrose infectada da diáfise, no entanto seu uso na metáfise dos ossos longos ainda é pouco explorado. Neste estudo relatamos uma série de casos de pseudoartrose infectada da metáfise do fêmur e da tíbia tratados com o uso de placas revestidas de cimento com antibiótico. Métodos: Os antibióticos usados foram gentamicina e/ou vancomicina. Os desfechos analisados na última visita ambulatorial foram controle de infecção, consolidação óssea, retorno às atividades diárias e qualidade de vida. Regressão linear bivariada foi usada para avaliar fatores individuais que afetaram a qualidade de vida dos pacientes. Um valor p<5% foi considerado estatisticamente significativo. Resultados: quinze pacientes adultos foram incluídos no estudo. S. aureus suscetível à meticilina foi isolado em 53,3% dos casos. O tempo médio de acompanhamento pós-operatório foi de 18 meses. Controle local da infecção e consolidação óssea radiográfica foram alcançados em 93,3% dos pacientes. Nenhum paciente apresentou sintomas recorrentes de infecção de sítio cirúrgico. Quatorze pacientes relataram ser capazes, mas não no nível pré-lesional ou no mesmo nível de antes da lesão, com 73,3% relatando nenhum problema em todas as cinco dimensões do EQ-5D-3L. Infecção persistente foi a única variável associada à redução da qualidade de vida a longo prazo. Conclusão: A placa revestida de cimento com antibiótico mostrou-se uma técnica cirúrgica viável e eficiente para o tratamento da pseudoartrose infectada da metáfise do fêmur e da tíbia.
Antibiotic cement-coated plate is a viable and efficient technique for the definitive management of metaphyseal septic nonunions of the femur and tibia
Authors: BIDOLEGUI FERNANDO , CODESIDO MARIANO , PEREIRA SEBASTIÁN , ABRAHAM AGUSTÍN , PIRES ROBINSON ESTEVES , GIORDANO VINCENZO
Published: January 2023

ABSTRACT Objective: the management of septic metaphyseal nonunions is challenging, with inconsistent outcomes. Antibiotic cement-coated implants have been demonstrated good outcome for diaphyseal infected nonunions, however there is no data in metaphyseal infected nonunions. Methods: fifteen adult patients with septic metaphyseal nonunions of the femur or tibia were treated with antibiotic cement-coated plates. The antibiotic cement-coated plate was prepared with either gentamicin or vancomycin. Outcome measures were infection control, bone healing, return to pre-injury level on daily activities, and quality of life at the last follow-up visit. A p value of <5% was considered significant. Results: Methicillin-susceptible S. aureus was isolated in 53.3% cases. Average postoperative follow-up time was 18 months. Local infection control and radiographic bone healing were adequately achieved in 93.3% patients. No patient presented recurrent symptoms of surgical site infection. Fourteen patients reported to be either able, or on the same level as before injury, with 73.3% reporting no problems in all five dimensions of the EQ-5D-3L. Persistent infection was the only variable associated with a reduced long-term quality of life. Conclusion: antibiotic cement-coated plate is a viable and efficient surgical technique for the definitive management of juxta-articular metaphyseal septic nonunions of the femur and tibia.
Estudo retrospectivo de rastreamento pré-operatoria mandatória de SARS-COV-2 na população pediátrica. Será hora de parar de testar nossos pacientes?
Authors: SOUZA CEZAR DANIEL SNAK DE , SARUHASHI TATIANA , LIMA MARIANA FONTES NEVILLE , OLIVEIRA JUNIOR FRANCISCO IVANILDO DE , CUMINO DEBORA DE OLIVEIRA
Published: January 2023

RESUMO A pandemia causada pelo novo coronavírus (SARS-COV-2) alterou a rotina de pacientes, profissionais e serviços de saúde em todo o mundo levando ao adiamento ou suspensão de muitos procedimentos cirúrgicos. Muitos serviços implementaram protocolos de triagem sistemática pré-operatória para SARS-COV-2. No entanto, segue incerta a eficácia da triagem sistemática de pacientes assintomáticos para SARS-COV-2 quando comparada com outras medidas de mitigação como o uso de máscaras e o distanciamento social apesar da aparente sensação de segurança conferida pela testagem pré-operatória de pacientes para SARS-COV-2. Sendo assim, descrevemos a experiência de dois anos de um hospital pediátrico (n=7.199) na triagem sistemática pré-operatória para SARS-COV-2 e comparamos a taxa de positividade mensal reportada pelo serviço em relação a taxa de positividade mensal regional do Estado de São Paulo. No período de Abril de 2020 a Fevereiro de 2022 houveram 187 (2,56%) RT-PCR positivos para COVID-19 dos quais 62.1% assintomáticos. Os sintomas mais comuns foram coriza (10,7%), febre (10%) e diarreia (8,7%). Dois pacientes faleceram em decorrência de sintomas relacionados a COVID-19. Mais estudos são necessários para determinar o impacto da testagem pré-operatória de RT-PCR para SARS-COV-2 em pacientes assintomáticos na mitigação da transmissão intra-hospitalar e na morbidade cirúrgica.
Transplante hepático no tratamento da lesão iatrogênica da via biliar
Authors: ZENI JOÃO OTÁVIO VARASCHIN , COELHO JULIO CEZAR UILI , ZENI NETO CLEMENTINO , FREITAS ALEXANDRE COUTINHO TEIXEIRA DE , COSTA MARCO AURÉLIO RAEDER DA , MATIAS JORGE EDUARDO FOUTO
Published: January 2023

RESUMO Objetivo: avaliar os resultados dos nossos pacientes que foram submetidos a transplante hepático por lesão iatrogênica do ducto biliar. Métodos: todos os pacientes que foram submetidos a transplante hepático para tratamento de complicações da lesão do ducto biliar foram incluídos no estudo. Os prontuários e protocolos de estudo desses pacientes foram analisados retrospectivamente para determinar características demográficas e clínicas, tratamento e desfecho dos pacientes. Resultados: de um total de 846 transplantes hepáticos realizados, 12 (1,4%) foram por lesão iatrogênica de via biliar: 10 (83,3%) ocorreram durante colecistectomia, 1 (8,3%) após quimioembolização e 1 (8,3%) durante laparotomia para controle de sangramento abdominal. A colecistectomia foi realizada por via aberta em 8 pacientes e por via laparoscópica em dois. Haviam 8 mulheres (66,7%) e 4 homens (33,3%), com média de idade de 50,6 ± 13,1 anos (variação de 23 a 70 anos). Todos os transplantes foram realizados com fígados de doadores cadavéricos. O tempo operatório médio foi de 565,2 ± 106,2 minutos (variação de 400-782 minutos). A reconstrução biliar foi realizada com hepaticojejunostomia em Y de Roux em 11 pacientes e coledococoledocostomia em um. Sete pacientes morreram (58,3%) e cinco (41,7%) estavam vivos durante um seguimento médio de 100 meses (variação de 18 a 118 meses). Conclusão: o transplante hepático em pacientes com lesão iatrogênica das vias biliares é um procedimento complexo com elevada morbimortalidade.
Liver transplantation for the treatment of iatrogenic bile duct injury
Authors: ZENI JOÃO OTÁVIO VARASCHIN , COELHO JULIO CEZAR UILI , ZENI NETO CLEMENTINO , FREITAS ALEXANDRE COUTINHO TEIXEIRA DE , COSTA MARCO AURÉLIO RAEDER DA , MATIAS JORGE EDUARDO FOUTO
Published: January 2023

ABSTRACT Objective: to assess the outcomes of our patients who were subjected to LT for iatrogenic bile duct injury. Methods: all patients who underwent LT for treatment of complications of biliary duct injury were included in the study. Medical records and study protocols of these patients were retrospectively analyzed to determine demographic and clinical characteristics, treatment, and outcome of the patients. Results: of a total of 846 liver transplants performed, 12 (1.4%) were due to iatrogenic bile duct injury: 10 (83.3%) occurred during cholecystectomy, 1 (8.3%) following chemoembolization, and 1 (8.3%) during laparotomy to control abdominal bleeding. Cholecystectomy was performed by open access in 8 patients and by laparoscopic access in two . There were 8 female (66.7%) and 4 male (33.3%) with a mean age of 50.6 ± 13.1 years (range 23 to 70 years). All transplants were performed with livers from cadaveric donors. The mean operative time was 558.2 ± 105.2 minutes (range, 400-782 minutes). Biliary reconstruction was performed with Roux-en-Y hepaticojejunostomy in 11 patients and choledochocholedochostomy in one. Seven patients died (58.3%) and five (41.7%) were alive during a mean followed up of 100 months (range 18 to 118 months). Conclusion: liver transplantation in patients with iatrogenic bile duct injury is a complex procedure with elevated morbimortality.
Work-related factors in the etiology of symptoms of post-traumatic stress among first responders: the Brazilian Firefighters Longitudinal Health Study (FLoHS)
Authors: Vasconcelos Alina Gomide , Lima Eduardo de Paula , Teoh Kevin , do Nascimento Elizabeth , MacLennan Sara , Cox Tom
Published: January 2023

Abstract: Two important aspects must be accounted for when discussing the mental health of first responders and, in particular, their report of post-traumatic stress symptoms (PTSS). The first concerns the provision of quantitative data from longitudinal study designs, the second concerns the sophistication of the work-related model used to frame such studies. This is a report on the development of a model for Brazilian firefighters who also work as first responders, from the establishment of a longitudinal panel design study, the Brazilian Firefighter Longitudinal Health Study (FLoHS). The first objective was to compare trainee and active firefighters based on their follow-up data with a nationwide sample of similarly aged Brazilians. The second was to test the effect that operational and organizational experiences had on firefighters’ PTSS level during follow up. At baseline, trainee firefighters came from higher socioeconomic backgrounds, were healthier and less exposed to trauma compared to a similarly aged national sample. At follow up, they reported higher prevalence of smoking, sleep problems, anhedonia and were more likely to be overweight. PTSS was predicted by operational and organizational stressors, even when controlled for health status at baseline. The results present not only the differences in the predictive status of operational and organizational events in relation to PTSS, but also how the effects of such events might interact. The data suggest the need for evidence-based interventions, support provided and changes at work environments to improve report rates for mental health in general and for PTSS in particular.
Construção de modelo teórico-lógico e matriz de julgamento para avaliação da efetividade do Núcleo Ampliado de Saúde da Família e Atenção Básica
Authors: Dias Maria Socorro de Araújo , Silva Lielma Carla Chagas da , Carvalho Francisca Andreza Nascimento , Moita Marina Pereira , Rodrigues Paloma de Vasconcelos , Machado Maria de Fátima Antero Sousa , Silva Lucilane Maria Sales da , Brito Maria da Conceição Coelho
Published: January 2023

A atenção básica requer processos de trabalho orientados pelo agir interprofissional colaborativo para responder às necessidades de saúde. O Núcleo Ampliado de Saúde da Família e Atenção Básica (NASF-AB) atua como importante dispositivo para ampliar as possibilidades de cuidado nesse cenário. Objetiva-se descrever o processo de construção de um modelo teórico-lógico e matriz de julgamento para avaliação da efetividade do NASF-AB. Foi realizado um estudo avaliativo, de abordagem descritivo-qualitativa com uso de pesquisa documental, em que foram selecionados 11 documentos regulamentadores do processo de trabalho do NASF-AB para subsidiar o modelo teórico-lógico. Na elaboração da matriz de julgamento para avaliação da efetividade do NASF-AB, consideraram-se os conceitos fundamentais e as competências esperadas, com a definição de indicadores e critérios para uma avaliação escalonar, a qual permite classificar o NASF-AB em efetivo, potencialmente efetivo, com baixa efetividade e não efetivo. Tanto a estruturação do modelo quanto a aplicação da matriz e sua expressão gráfica são instrumentos que subsidiam o funcionamento ideal do NASF-AB, sendo capazes de orientar a tomada de decisão na gestão e no processo de trabalho, nas dimensões assistencial e pedagógica. Os produtos desta investigação se constituem em dispositivos teórico-metodológicos para subsidiar a avaliação da efetividade do NASF-AB e permitir identificar insuficiências e potências de sua atuação.
GÊNERO NAS AULAS DE CIÊNCIAS: UMA ANÁLISE DA APRENDIZAGEM CONCEITUAL
Authors: FRANCO LUIZ GUSTAVO , MUNFORD DANUSA
Published: January 2023

RESUMO: A temática do gênero assumiu um lugar central nas discussões no campo da educação. Neste artigo, discutimos relações de gênero no contexto específico do campo da Educação em Ciências da Natureza, uma área que tem se dedicado, de modo crescente, ao estudo de relações de gênero. Apesar de avanços no campo, ainda são escassos os estudos que relacionam gênero à aprendizagem de conceitos científicos no cotidiano da sala de aula. No presente estudo, exploramos interações discursivas em uma turma do 1° ano Ensino Fundamental com o objetivo de analisar o papel do gênero na construção de oportunidades de aprendizagem de ciências. Para isso, nos apoiamos em propostas teóricas de Judith Butler sobre gênero, e orientamos as análises a partir da Etnografia em Educação como lógica de pesquisa. As aulas analisadas indicam que conhecimentos conceituais de ciências estavam articulados a processos de reiteração/contestação da norma de gênero. Tais negociações exerceram um papel central na aprendizagem sobre a biologia de um inseto, em particular, sobre o conceito de dimorfismo sexual. O estudo se une a outras pesquisas que apontam a relevância das discussões sobre gênero na educação, incluindo a disciplina escolar Ciências e seus conceitos.
ESOPHAGOCELE DUE TO TWO TIMES CAUSTIC INGESTIONS: RESECTION THROUGH VIDEOTHORACOSCOPY
Authors: ALVES Iuri Pedreira Filardi , TERCIOTI JUNIOR Valdir , COELHO NETO João de Souza , FERRER José Antonio Possatto , ANDREOLLO Nelson Adami , LOPES Luiz Roberto
Published: January 2023

ABSTRACT BACKGROUND: Caustic ingestion is still a health problem of utmost importance in the West. In developing countries, this incident remains at increase and it is associated with unfavorable factors like social, economic, and educational handicaps, besides a lack of prevention. Esophagocele is a rare consequence of caustic ingestion. AIM: We aimed to describe a patient with multiple caustic ingestions who presented an esophagocele resected by videothoracoscopy. METHODS: A woman ingested caustic soda when she was only 17 years old in a suicidal attempt during a depressive crisis. Initially, she was submitted to a retrosternal esophagocoloplasty with the maintenance of her damaged esophagus. After 1 year of this first surgery, she ingested caustic soda again in a new suicidal attempt. Her transposed large bowel in the first surgery became narrow, being replaced in a second surgery by a retrosternal esophagogastroplasty. Still, at the second surgery, her damaged esophagus remained in its original position in the posterior mediastinum. However, after 5 years, she developed an esophagocele. RESULTS: The esophagocele was resected through videothoracoscopy in a prone position, employing four trocars. The postoperative was uneventful. CONCLUSION: Esophageal exclusion must always be recorded because esophagocele presents unspecific symptoms. The videothoracoscopy in a prone position is an excellent technical option to resect esophagoceles.
WHICH LESIONS ARE AT HIGHER RISK OF DEVELOPING COLORECTAL CARCINOMAS: SUPERFICIALLY ELEVATED SERRATED LESIONS OR DEPRESSED LESIONS?
Authors: PARADA Artur Adolfo , VENCO Filadelfio Euclydes , VARCA-NETO Miguel Reynaldo , EL IBRAHIM Roberto , POLETTI Paula Bechara , BRITO Helcio Pedrosa , SARE Heloisa de Fátima , MALAFAIA Osvaldo
Published: January 2023

ABSTRACT BACKGROUND: There are lesions that are still being missed in colonoscopy. Many of those could be superficially elevated serrated lesions or depressed ones. AIMS: The aim of this study was to compare the histopathological characteristics of these lesions and their risks for submucosal carcinoma. METHODS: This is a retrospective, cross-sectional, and observational study comparing 217 superficially elevated serrated lesions larger than 5 mm resected by colonoscopies (G1) with 558 depressed lesions (G2). RESULTS: In G1, 217 lesions were found in 12,653 (1.7%) colonoscopies; in G2, 558 lesions were found in 36,174 (1.5%) colonoscopies. In G1, 63.4% were women and in G2, there was no gender predominance. The average size of G1 was 16.2 mm and G2 was 9.2 mm (p<0.001). G1 predominated on the proximal colon and G2 on the distal and rectum (p<0.001). In G1, there were 214 (98.6%) low-grade intramucosal neoplasia and 3 (1.4%) high-grade intramucosal neoplasia. Excluding 126 hyperplastic polyps and considering 91 sessile serrated adenomas in G1, we observed 88 (96.7%) low-grade intramucosal neoplasia and 3 (3.3%) high-grade intramucosal neoplasia; in G2, we observed 417 (74.7%) low-grade intramucosal neoplasia, 113 (20.3%) high-grade intramucosal neoplasia, and 28 (5.0%) submucosal adenocarcinomas (p<0.001). CONCLUSION: Depressed lesions significantly had more high-grade intramucosal neoplasia and more invasive carcinomas in the submucosal layer than superficially elevated serrated lesions and more than superficially elevated sessile serrated adenomas.
Spatial Clustering of Extreme Annual Precipitation in Uruguay
Authors: Santiñaque Florencia , Kalemkerian Juan , Renom Madeleine
Published: January 2023

Abstract The main objective of this work is to study the existence of spatial patterns maximum annual rainfall (through daily observations) within the territory of Uruguay and to show the application of two new statistical tools recently proposed. In the first stage, the distributions of maximum annual precipitation at each meteorological station will be studied. In the second stage, spatial clustering methods will be applied. To get the distribution of the maximum of each station, we have used a truncated Cramér-von Mises hypothesis test (the first statistical tool) and showed that it improves on the performance of the classic likelihood ratio test. It was found that in 18 study locations the distribution that best fits the data is of the Gumbel type, and for the other two, it is of the Fréchet type. Regarding the clustering methods, two methodologies were used, one of them was to perform clustering with the estimated parameters and the other was the PAM methodology using the F-madogram as distance, highlighting the homogeneity throughout the Uruguayan territory. Another novelty of this work (the second statistical tool) consists in including, as a complement to the clustering, the recently proposed independence test based on recurrence rates.
Desagregação de Chuvas Diárias no Estado de Mato Grosso
Authors: Sabino Marlus , Souza Adilson Pacheco de , Almeida Frederico Terra de , Zolin Cornelio Alberto , Lisboa Luana
Published: January 2023

Resumo As chuvas intensas é uma variável climática importante no planejamento de obras hidráulicas, sendo usualmente caracterizada pelas curvas de intensidade-duração-frequência (IDF) obtidas de dados pluviográficos. Em locais que não dispõem de estações pluviográficas as curvas IDF podem ser obtidas por métodos de desagregação de chuvas diárias. Assim, esse estudo ajustou os coeficientes de desagregação de chuvas de 1 dia e os parâmetros da equação de Bell no Estado de Mato Grosso e verificou qual método proporciona melhores resultados na estimativa de chuvas de diferentes durações e tempos de retorno. O ajuste dos métodos de desagregação de chuvas de 1 dia e equação de Bell foi realizado pela análise das relações entre as chuvas obtidas das curvas IDF de 14 estações pluviográficas do estado e das séries anuais de chuva máxima diária, nos mesmos locais, ajustados à distribuição generalizada de valores extremos. Devido à baixa frequência de chuvas com duração superior a 360 min, o primeiro coeficiente de desagregação de chuvas obtidos foi de 1 dia em 6 horas (0.53). Os parâmetros médios da equação de Bell (α: 0.19, β1: 0.99, β2: 0.96, β3: 0.99, γ: 0.16) apresentaram ajuste satisfatório com R2 igual 0.88. As raízes dos erros médio quadrático de ambos os métodos variaram de 3.5 mm (chuvas de 10 min) a 18.7 mm (chuvas de 360 min), com um viés inferior a 10%. O ajuste de ambos os métodos foi responsável por reduzir os erros associados quando comparado aos coeficientes nacionais, sendo assim, indicados para a obtenção de chuvas de durações inferiores a 1 dia a partir de dados pluviométricos no Mato Grosso.
Terrestrial gastropods as Fragaria x ananassa pests in southern Brazil: morphological identification
Authors: Landal Maitê Cristina Tucholski , Bach Renata Prieto , Gomes Suzete Rodrigues , Botton Marcos , Zawadneak Maria Aparecida Cassilha
Published: January 2023

ABSTRACT: Considering the damage caused by terrestrial gastropods in strawberry producing areas in southern Brazil, this study aimed to i) identify the species associated with Fragaria x ananassa in rural properties in municipalities of Paraná State, Brazil; ii) describe and illustrate the diagnostic morphological and conchology features of the mollusk species; iii) construct an illustrated key based on these morphological and conchology features; iv) analyze two species collected in March 2017 to investigate the possible occurrence of parasitic nematodes of medical importance. Taxonomic determination of the mollusks was performed through morphological analysis of samples, and parasitological analysis was carried out using artificial digestion. The following gastropod species were identified: Bradybaena similaris (Bradybaenidae), Rumina decollata (Subulinidae), Deroceras leave (Agriolimacidae), Limacus flavus (Limacidae), and Meghimatium pictum (Philomycidae). Rumina decollata, L. flavus,and M. pictum were recorded for the first time as damaging strawberries in Brazil. No larvae of medical or veterinary importance, associated with samples, were reported. The main diagnostic features are described and illustrated. Besides, the potential of the gastropods as crop pests and vectors of nematodes associated with zoonotic diseases are discussed. Results can facilitate identification of gastropod species in strawberry crops and provide background information for future studies on bioecology and pest control.
Intra-abdominal hypertension secondary to chronic diaphragmatic rupture in a dog
Authors: Silva Paloma Helena Sanches da , Giachini Raquel , Coelho Nathália das Graças Dorneles , Barbosa Breno Curty , Santana Ranielle Stephanie Toledo , Faria Junior Domingos de , Malm Christina , Beier Suzane Lilian , Luz Marcelo Rezende , Freitas Patrícia Maria Coletto
Published: January 2023

ABSTRACT: Intra-abdominal hypertension (IAH) is the persistent increase of intra-abdominal pressure (IAP) that could be caused by several pathologies. It is capable of promoting organ dysfunction, thereby increasing the mortality rate of human patients. As for cats and dogs, there are still few reports on how this pressure can be monitored and treated as a routine for admitted and hospitalized animals and on its relationship with the mortality of the patients. Therefore, the objective of this paper was to report a case of IAH secondary to chronic diaphragmatic rupture in a dog, which was treated with a temporary abdominal closure (TAC). A bitch was admitted to the veterinary hospital to undergo an elective ovariohysterectomy when it was diagnosed with a diaphragmatic rupture and displacement of the liver and intestinal loops in the chest. After repositioning these structures in the abdominal cavity, tension was observed in the abdomen. A temporary abdominal closure was then performed with a Bogota bag. Immediately after the surgery, the IAP was measured, presenting a value of 15 mmHg, indicating that there was an increase in intra-abdominal pressure. The animal was hospitalized, and IAP was monitored. After 24 hours, IAP was 5.8 mmHg when the Bogota bag was removed, and definitive celiorraphy was performed. The patient showed satisfactory clinical progress and was discharged 72 hours after the surgical procedure. The treatment used for IAH proved to be effective and contributed to the quick and satisfactory recovery of the patient.
Physicochemical techniques for determining the composition of canine and feline uroliths: a literature review
Authors: Gomes Veridiane da Rosa , Ariza Paula Costa , Queiroz Layla Livia de , Fioravanti Maria Clorinda Soares
Published: January 2023

ABSTRACT: Urinary lithiasis has been reported as a problem that affects humankind since ancient times and has been described in several animal species. The condition is a consequence of other diseases that may be present in the urinary system or related to other body disorders. The stone composition needs to be analyzed to identify the possible causes that led to the formation and development of uroliths. For this, several techniques are currently available, some of which are promptly accessible, while others are not. Thus, this literature review aimed to perform a brief introduction on urolithiasis, present the most used techniques in the analysis of the composition of canine and feline uroliths and point out the advantages and disadvantages of each technique.
Intra-abdominal torsion of a non-neoplastic cryptorchid testis in an adult dog
Authors: Primaz Sandy Liara , Jacques Aline de Moura , Risso Natalia Horstmann , Mestieri Maria Ligia de Arruda , Oliveira Marília Teresa de , Trost Maria Elisa , Strey Fabiana Wurster , Beckmann Diego Vilibaldo
Published: January 2023

ABSTRACT: Intra-abdominal or intrascrotal testicular torsion in dogs occurs due to spermatic cord rotation. Dogs with testicular torsion commonly present severe pain and require surgical intervention. Torsion of intra-abdominal retained testicles in cryptorchid adult dogs is often associated with the presence of testicular neoplasia. Herein, we reported the case of a 5-year-old male poodle with uncommon intra-abdominal testicular torsion (ITT) of a non-neoplastic testicle. The dog was referred to the veterinary hospital with acute abdominal pain in the hypogastric region. An intra-abdominal gonad and alterations compatible with testicular torsion were visualized during ultrasound examination. Orchiectomy and histopathological analysis of the testes confirmed the diagnosis of ITT in the absence of neoplasia. The patient recovered uneventfully from the situation. This report showed that ITT can occur in adult dogs in the absence of testicular neoplasia and reinforce the message that it should be included as a differential diagnosis in cases of acute abdominal pain in cryptorchid dogs. Furthermore, the ultrasound examination in this case of pain in the hypogastric region was decisive for the diagnosis of ITT.
Water consumption and water use efficiency of ‘Biquinho’ pepper in hydroponic cultivation with brackish water
Authors: Bione Maria Augusta Amorim , Cova Alide Mitsue Watanabe , Paz Vital Pedro da Silva , Santos Ubirani Oliveira , Rafael Maria Raphaela Severo , Modesto Francisco José Nunes , Gheyi Hans Raj , Soares Tales Miler
Published: January 2023

ABSTRACT: The knowledge of water consumption and the efficiency of water use by crops is extremely important in the elaboration of agronomic and hydraulic projects of hydroponic systems. Thus, the present study determined the water consumption and water use efficiency of ‘Biquinho’ pepper cultivated in the hydroponic system using seven levels of electrical conductivity of the nutrient solution (ECsol) of 2.70, 3.64, 4.58, 5.28, 6.09, 6.90, and 7.77 dS m-1 and six replicates in randomized blocks. The hydroponic system used was the Nutrient Film Technique (NFT). The water consumption per plant was determined at an interval of ten days in the crop cycle (120 days after transplanting). The maximum mean daily water consumption was equal to 5.88 L plant-1 during the period 111-120 DAT, for ECsol of 4.58 dS m-1. The maximum water consumption for the crop cycle (120 DAT) was 275.66 L per plant for an estimated ECsol = 4.11 dS m-1. The highest water use efficiency (WUE), based on the total production of fruit fresh mass (ripe and unripe fruits) of ‘Biquinho’ pepper was 10.84 kg m-3 up to an estimated ECsol of 5.18 dS m-1, with an exponential reduction thereafter. The salinity of the nutrient solution, biomass production, and evapotranspiration are factors that influence the most water consumption of ‘Biquinho’ pepper.
The impact of agricultural comprehensive development on agro-ecological efficiency of China - evidence from perspective of scale and structure
Authors: Zhang Tongyue , Hou Mengyang , Chu Liqi , Wang Lili
Published: January 2023

ABSTRACT: Promoting the agricultural sustainable development is one of the core objectives of agricultural comprehensive development (ACD), and the core of agricultural sustainable development lies in enhancing agro-ecological efficiency (AEE). Based on inter-provincial panel data from 2003-2017, the AEE was measured by a unexpected super-efficient SBM model. From the perspective of investment scale and investment structure, the impact of investment scale in ACD on AEE was examined using a panel econometric model, then characterizing the investment structure by the proportion of government funds in the investment of ACD, examining the non-linear relationship between investment structure of ACD and AEE seeking a reasonable proportion of government expenditure. Finally, a spatial econometric model was constructed to test the spatial spillover effect of the scale and structure of investment in ACD on AEE. Results showed that: (i) AEE of China is on the rise overall, but the efficiency level is still low and there is large scope for improvement. (ii) Due to the inefficient use of funds and the lag in the transformation of agricultural benefits, the scale of investment in ACD has a significant negative impact on AEE in the current period. (iii) The impact of investment structure of ACD on AEE presents a significant “inverted N” relationship, and the optimal proportion of government fund investment structure is 76.71%. The reasonable structure of investment in ACD at different food functional areas shows differences. (iv) After considering the spatial effect, the impact of ACD remains robust, but the spatial spillover effect prolongs the time lag of this impact of investment scale and starts to have a positive impact in the 2nd year after the investment. Guarantee the investment scale in ACD, reduce financial redundancy, establish a cooperation mechanism between ACD and agricultural ecological protection in neighboring areas, and increase the introduction of private capital can achieve sustainable development of agricultural economy.
Cerebral infarction and thrombotic meningoencephalitis in a calf due to candidiasis
Authors: Alves Rodrigo Cruz , Soares Yanca Góes dos Santos , Carvalho Fabrício Kleber de Lucena , Maia Lisanka Ângelo , Barros Claudio Severo Lombardo de , Riet-Correa Franklin , Dantas Antonio Flávio Medeiros , Galiza Glauco José Nogueira de
Published: January 2023

ABSTRACT: We described a case of cerebral infarction and thrombotic meningoencephalitis due to candidiasis in a seven-month-old calf. The death occurred three days after the onset of apathy, fever, and the head’s lateral deviation to the left. Macroscopic changes in the brain consisted of asymmetry of telencephalic hemispheres; the right hemisphere was enlarged, causing cerebellar herniation. A focally extensive red area was observed on the surface of the right occipital lobe. At cross-sections of the fixed brain, the lesions revealed to be extensive, red-brown, soft or cavitated areas affecting the white and grey matter from the level of the thalamus to the cerebellum and compressing subjacent structures. Histologically, there was acute, coalescent, multifocal necrosupurative meningoencephalitis, associated with vasculitis, congestion, thrombosis, edema, infarction, and intralesional fungal hyphae. The diagnosis of cerebral infarction and thrombotic meningoencephalitis due to candidiasis was made by the pathological changes, the staining and morphological characteristics of the agent, and immunohistochemistry. The cerebral infarction and thrombotic meningoencephalitis in cattle can result from vascular lesions due to infection by Candida sp.; although uncommon, this case demonstrated that candidiasis should be part of a list of differential diagnoses of severe brain injuries in cattle.
Insecticide activity of a peptidase inhibitor isolated from Anadenanthera macrocarpa seeds against Anagasta kuehniella
Authors: Leite Welington de Araújo , Jacobowski Ana Cristina , Macedo Maria Lígia Rodrigues
Published: January 2023

ABSTRACT Protease inhibitors (PIs) are a part of the plant defense system and reduce the proteolytic activity of the digestive enzymes of insect pests. The current study aimed to isolate and characterize an inhibitor of trypsin (AmTI) within the seed of Anadenanthera macrocarpa (Benth) (Leguminosae-Mimosoideae). Moreover, we tried to assess the defense mechanism of the larvae of Anagasta kuehniella against this inhibitor. Protein seed extracts were purified using Sephadex G-50 and trypsin-Sepharose columns. Electrophoresis revealed the molecular weight of the inhibitor to be 25 kDa. The stability evaluation demonstrated that the inhibitor was not denatured at temperatures of up to 60 °C, pH 2-10, and concentrations of up to 100 mM dithiothreitol for one hour. The inhibitor reacted in a 1:1 ratio with bovine trypsin with an inhibition constant [Ki] = 2.517 ´ 10-8. Incorporating the inhibitor in a 1 mg per 100 mg proportion of artificial diet offered to A. kuehniella larvae led to a significant difference in the weight and survival of larvae of the fourth instar compared to the control. AmTI acted on the enzymatic activities of trypsin and chymotrypsin, not allowing until the fourth larval instar, A. kuehniella, to create adaptations against the inhibitor, as it had a simultaneous effect on larval weight and mortality. Therefore, a new trypsin inhibitor showing inhibitory activity against the digestive enzymes trypsin and chymotrypsin from A. kuehniella was isolated, indicating that these activities are correlated with the deleterious effects of this insect.