bluuebunny/crossref_metadata_2025 huggingface dataset:
TO THE QUESTION ABOUT THE EFFECTIVENESS OF CLINICAL EXAMINATION OF PREGNANT WOMEN
Authors: Kabochkin A A , Piven E A
Published: October 2016

The assessment of deadlines for dispensary registration of pregnant and regularity of their observations are presented in article and also the relation of the surveyed women to work of "School of pregnant women". We used in the work the results of the survey 672 postpartum women living in Ryazan.
INTRAARTERIAL REGIONAL INFUSION TRACT IN THE DIAGNOSIS AND TREATMENT OF ACUTE PANCREATITIS
Authors: Lazutkin M V , Ivanusa S Y , Tikhomirova O E
Published: October 2016

The study used the results of the examination and treatment of 41 patients with acute pancreatitis who underwent endovascular catheterization of the celiac trunk, followed by intra-regional perfusion of the pancreas. The clinical results of intra-regional perfusion of the pancreas showed efficacy in the prevention of septic complications, progression of pancreatic necrosis in patients with aseptic forms of severe pancreatitis. Create intraarterial infusion tract allows multislice spiral computed tomography celiacography in order to increase the information content ray imaging zones destruction of the pancreas.
AUTOAGGRESSIVE BEHAVIOR AND ALCOHOL ADDICTION AMONG PHYSICIANS (LITERATURE REVIEW)
Authors: Ozol S N , Shustov D I
Published: October 2016

On the basis of data, published in foreign and domestic literature, the analysis of problem of autoagressive behavior and alcohol addictions among physicians was performed. In addition, the question of professional deformation was considered.
OVERVIEW: FEATURES OF VERTEBROGENIC LUMBOSACRAL CHRONIC PAIN SYNDROME
Authors: Zhadnov V A , Erkhova L N
Published: October 2016

There are a biopsychosocial pain model, it consist of biological (anatomical, physiological), sociocultural (level of education, traditions) and psychological (cognitive, affective, behavioural) components. Also there are nociception (myofascial) and neuropathic (compression radiculopathy) components. The anatomical condition of the vertebral-motor segment often not correlated with the severity of pain syndrome. Assess the state of the peripheral segmental apparatus, peripheral nerves of the lower extremities, you can use stimulation ENMG.
ORGANIZATION OF MEDICAL ASSISTANCE TO THE WORKING POPULATION OF CLOSED ADMINISTRATIVE-TERRITORIAL EDUCATION
Authors: Fomin E P
Published: October 2016

The health status of the population of closed administrative-territorial education (CATE) and its individual groups are investigated to a number of studies mainly aimed to identifying the effects of various professional factors on health. However, only a few works were carried out to improve the health care for CATE workers.
MORPHOLOGICAL CHANGES OF VASCULAR WALL AT DIFFERENT STAGES OF EXPERIMENTAL THROMBOSIS
Authors: Sushkov S A , Nebilitsin Yu S , Samsonova I V , Markautsan P V
Published: October 2016

Objective. To study interactive structural changes of vascular wall at experimental modeling thrombosis of the inferior cava vein system deep veins. Thrombosis caused by ligation of external iliac vein and injection of thrombin (40 /kg) into femoral vein. At the outset thrombotic process causes local destruction of endotheliocytes plasmolemma and karyolemma. Clot compressive effect upon veinous wall blocks severe and rapid endothelium swelling. At 30-th min leucocytes appear in peripheral parts of clot and along the vein intima. Transendothelial leucocytes migration appears on the 60-th min, that more severe increase the endothelium damage and, as result, focal desquamation of these cells. By the 12-24 hours increase of collagen and elastic fibers was distinct registered in the intima.
MOSAICISM OF HYALINE CARTILAGE: QUANTITATIVE MORPHOLOGICAL STUDY ON RABBIT ELBOW JOINT
Authors: Novochadov V V , Alekseenko A Yu , Krylov P A , Shuvalova E Yu
Published: October 2016

To study the heterogenecity of hyaline cartilage we have analyzed the tissues of elbow joint received from six intact Chinchilla rabbits. Classic histological assays, step-by-step scanning, and quantitative morphological analysis were performed. The revealed phenomenon at least concluded in an available of mosaic plots (microclusters), different from the environment of the numerical density of chondrocytes, structure and optical density of cartilage matrix. These microclusters took up to 40% of cartilage volume, they could be described as a polygon truncated pyramids with a diameter cross section about 60-100 microns near the basophil line and extending to 100-150 microns by superficial zone of the cartilage. The revealed phenomenon was matched to the biomechanics of the joints to provide for optimal redistribution of static and dynamic loads on the articular surface.
INTERFERON GAMMA-CYTOKINE WITH ANTIVIRAL, IMMUNOMODULATORY AND ANTITUMOR ACTION
Authors: Sologub T V , Tsvetkov V V , Deeva E G
Published: October 2016

Interferon gamma is a unique drug with anti-virus, anti-tumor and immunomodulatory activity. Thanks to the latter its quality interferon gamma was added to cytokines - regulators of immune responses. The study of this interesting cytokine can open up broad prospects for the treatment of patients not only with lymphoproliferative diseases, but patients with cancer and infectious diseases.
FEATURES COMMON CANCERS BASED TYPOLOGICAL PROPORTIONAL SAMPLE (ON MATERIALS NIZHNY NOVGOROD REGION)
Authors: Denisenko A N , Kamaev I A , Grib M N , Podushkina I V , Oreshina A V
Published: October 2016

The article shows the levels and dynamics of morbidity and mortality, as well as geographical features of prevalence of cancer in the Nizhny Novgorod region in the 2010-2012 years. The necessity of forming a multi-level system of the population cancer care and the need for primary and secondary prevention of cancer are also shown.
Features of the factor structure of the quality of life of women with chronic diseases neurological and women undergoing surgery for pelvic prolapse
Authors: Molostvova G V , Vasina I V , Filimonov V B , Vasin R V
Published: October 2016

In the article the peculiarities of the quality of life in neurological patients with chronic vascular diseases of the brain, chronic vertebral pathology and patients undergoing surgery for pelvic prolapse. It is shown that the structure of the quality of life of patients with neurological profile, includes the factors of emotional character and illustrate the response of patients to the chronic nature of the disease. The structure of the quality of life of the patients patients flatter associated, intense, illustrates the pronounced state of adaptation to life in the postoperative period. Suggested tactics of providing medical care to patients with different types of manifestations of the features of quality of life.
Quality of life in patients after total cement or cementless hip arthroplasty
Authors: Fedoseev A V , Litvinov A A , Chekushin A A , Filonenko P S , Al Mansour A Y , Yurchikova E E
Published: October 2016

In this article, the authors compared the quality of life of patients after total hip arthroplasty with cementless (group 1) and cement (group 2) fixation of prosthetic components. Obtained similar data in both groups. The authors recommend cementless total hip arthroplasty for fractures of the femoral neck as an alternative to cement fixation method in terms of osteoporosis.
Innovative technologies in the diagnostics and rehabilitation treatment of patients with essential hypertension
Authors: Sokolov A V , Svintsova S E , Artyomova N M
Published: October 2016

The work presents the rational use of the indicators of functional reserves for objective assessment of clinical and functional state and treatment outcomes among patients with hypertension stage 2, grade 1-2 on the sanatorium stage. In the study involving 40 patients demonstrated that the use of low-frequency field generated by the apparatus “Hivamat” - 200 improves the results of complex sanatorium treatment of these patients and in particular allows to achieve more rapid regression of clinical manifestations of the disease and more pronounced increase of functional reserves.
Modern clinical and morphological approach to early gastric cancer
Authors: Mikhaleva L M , Birukov A E , Plahov R V
Published: October 2016

The article presents the results of histological examination of early gastric cancer, endoscopic submucosal remote resection. An algorithm for the morphological study: methods of histological, histochemical and immunohistochemical processing tissue samples, understands the sequence of morphological analysis with findings and conclusions on the effectiveness of endoscopic surgery.
Patient evaluation of general practitioners as a tool to improve the quality of primary health care
Authors: Odrinskiy V A
Published: October 2016

The analysis of patient satisfaction (n = 424) of the work of general practitioners and health care institutions at the primary health care level with the use of standardized EUROPEP questionnaires was carried out in Ukraine. The results show lower evaluation by patients of Ukrainian doctors activity and primary healthcare institutions on comparison with European data. For improve this situation need to implement organizational and educational activities.
Hydrochemical status of surface waters the city of Ryazan
Authors: Podol S R , Popova Z I
Published: October 2016

Defined hydrochemical parameters of water quality urban water bodies of the city of Ryazan, the estimation of priority pollutants in river water. They are the ammonium nitrogen, nitrite nitrogen and organic matter. Best hydrochemical parameters among the studied objects have Borkowska career, the worst - the river Trubezh. It is important that the content of petroleum products, chlorine and heavy metals (zinc, copper and lead) in all objects below the exposure limits. The total hardness of water is generally below the exposure limits. The primary measure to improve water quality can be considered as the clearing and shores. This will increase the volume of water in the river, will accelerate its purification from impurities, respectively, and will improve water quality.
Estimation results taste sensitivity in remote dates after prosthesis in patients with galvanism, the use of non-removable prosthetic devices
Authors: Kotov K S , Guskov A V
Published: October 2016

The paper presents results of investigation of non-removable dentures on the quality and level of taste sensations in patients with different levels of potential difference (the magnitude of galvanic currents) in the mouth, using non-removable dentures from 6 months to a year, and the estimated degree of operational deterioration of prostheses and its relationship with the value of galvanic currents and the degree of disturbance of taste sensitivity to sweet, salty and sour. It is shown that there is a statistically significant positive direct-time relationship between excess level galvanic currents in the mouth, increased destruction of prostheses and change of taste sensitivity to sour and salty.
Bacteriological examination of malignant tumors (retrospective overview)
Authors: Rubtsov B V
Published: October 2016

In recent years multiple reports regarding the bacterial infections and oncogenesis emerged. Some modern researchers make a guess about possible etiological role of microorganisms in tumorogenesis. Meanwhile, in the past, until the mid XX century the connection between oncogenesis and bacterial infections was extensively studied. There were numerous clinical and experimental evidences, pointing the participation of bacteria in the tumor formation and pathogenesis. Owing to the revived interest to role, played by bacteria, in etiology and pathogenesis of malignant tumors we have made a retrospective overview of earlier works, dedicated to this problem.
Features of morphological and spatial structure of placenta at in the antenatal fetal hypoxia
Authors: Barinova I V , Savelev S V , Kotov Y B
Published: October 2016

The paper outlines results of morphological study of 55 placentas of fetuses died of antenatal hypoxia, in comparison with the results of the original X-ray micro- tomography of the placenta. Identified two subgroups of antenatal losses other than the maturity of the villi, and spatial localization of vasculopathy structural organization. It was revealed the features of the three-dimensional structure of the placenta during antenatal hypoxia with fetal loss, depending on the maturity of the villous tree.
Interrelations between individual peculiarities of the nervous system and effectiveness of reproduction of visual images by humans
Authors: Merkulova M A , Lapkin M M , Kulikova N A
Published: October 2016

In the article a probable influence of psychodynamic properties of the nervous system and of functional lateralization of functions on the effectiveness of reproduction of visual images by humans is discussed. The data presented in the article show that differences in reproduction of visual images among individuals are associated not only with expression of a psychodynamic property or extent of lateralization of functions, but rather with interrelations between them.
Monitoring behavioral risk factors for chronic noncommunicable diseases in 2014
Authors: Filippov E V
Published: October 2016

To estimate the prevalence of behavioral risk factors and awareness of the Ryazan area about them. The study included 367 people of the urban population aged 25-64 years living in the Railway area of Ryazan. Among the included in the study was 157 (42,8%) men and 210 (57,2%) women. Distribution of citizens by sex and age in the sample corresponds to the distribution by sex and age of the population of the Ryazan region (p0,05). In the study of harm from a variety of risk factors respondents gave less importance overweight, high blood pressure and nutrition, physical activity than smoking or alcohol. The most popular sources of information on risk factors was the Internet, television, and popular scientific literature. Among all the examined 35% of men and 8% of women currently smoke. 9% took more than 5-6 doses of alcohol for 1 time, indicating the need for building a culture of its use. 4,5% of respondents abused alcohol. Level of anxiety/depression of the population not changed - 40,3% Although not a small positive trend in reducing the prevalence of some risk factors (smoking, alcohol), their level is still high, and this dictates the need for further work to promote a healthy lifestyle, nutrition and combating the risk factors for cardiovascular diseases.
CLINICAL AND PSYCHOLOGICAL CHARACTERISTICS OF WOMEN WITH ENDOMETRIAL CANCER BEFORE AND AFTER THE SURGERY
Authors: Savin A I , Volodin B Y
Published: October 2016

The present article deals with the results of the investigation of clinical and psychological characteristics of 70 patients with endometrial cancer, which have had a hysterectomy. The comparison group consisted of 70 women with uterine myoma which had also been operated (amputation). Patients had been investigated before and after the surgery. The most patients with endometrial cancer had anxious type of reaction to the disease, the greatneed for independence and communication need. The received data can be used for psychotherapeutic treatment.
TO THE QUESTION ABOUT THE CAUSES AND CURES OF RECURRENCE OF GRAVES' DISEASE
Authors: Aristarkhov V G , Kvasov A V
Published: October 2016

The authors analyze the remote results of the treatment of 345 patients with Graves disease in this article. Principal reasons which determine thyroid status of patients after surgery in the nearest and remote observation period. The technique to eliminate the recurrence of Graves’ disease. For example, 26 patients shown the way and the results of the alternative treatment of relapse of Graves’ disease, by percutaneous 96% alcohol sclerotherapy in the hospital. As a result, 15 (57,7%) patients achieved a euthyroid state, in 3 patients (11,5 %) this method was ineffective.
Ultrastructural features uteroplacental region in early pregnancy with urogenital infections
Authors: Mikhalev S A , Mikhaleva L M , Barhina T G , Chernikov V P
Published: October 2016

The article presents the ultrastructural features of utero-placental area in early pregnancy with urogenital infection. The description of the ultrastructural changes in syncytiotrophoblast, decidual cells, multinucleated giant cells, blood vessels of the microvasculature.
THE PROGNOSIS OF METASTASIS OF THE OVARY ENDOMETRIOID CARCINOMA ON THE BASIS HISTOPATHOLOGICALLY INDICATORS NUCLEI OF TUMOR CELLS
Authors: Vorobeva O V , Novichkov E V
Published: October 2016

In operation, on the basis of a study of 76 cases of endometrioid ovarian cancer shows a significant role of quantitative and qualitative changes of nucleic acids in tumor cells, which are associated with increased likelihood of developing metastases. Also indicated on the role and importance of photometric and ploidometric diagnosis of uveal melanomas research in the practice of medical Oncology profile for the subsequent plan treatment of patients and the prognosis of the disease.
ADAPTATION OF PUPILS REGULATORY SYSTEMS (TYPES OF VEGETATIVE REGULATION) STUDENTS TO PHYSICAL ACTIVITY AT THE LESSON OF PHYSICAL CULTURE
Authors: Gorelik V V
Published: October 2016

In the conditions of educational process in secondary schools evaluated the types of vegetative regulation pupils with complex "Varikard 2.51" before and after the lesson of physical culture. Given a certain type of vegetative regulation of schoolchildren and correcting physical activity, warned dysregulatory manifestations of the body of pupils.
STUDY OF HEPATOPROTECTIVE ACTIVITY OF FLOWERS TANSY POLYSACCHARIDE COMPLEX
Authors: Engalycheva E E , Yakusheva E N , Sychov I A , Shchulkin A V
Published: October 2016

Polysaccharide complex extracted from tansy (Tanacetum vulgare L.) flowers is pectines type glucuronolactone. Its hepatoprotective activity was assessed on the model of acute toxic hepatitis caused by introduction of carbon tetrachloride 50% solution. It was found that the polysaccharide reduced the asparte aminotransferase activity, decreases the level of malondialdehyde, increases the amount of free SH-groups and glutathiontransferase activity in lysate of erythrocytes, i.e. polysaccharide complex has a pronounced hepatoprotective and antioxidant properties.
ANALYSIS IMBALANCE IN THE PROVISION MIDWIFE ON THE STAFF OF OBSTETRIC SERVICES THE RYAZAN AREA WITHIN THE CONTEXT OF CONTEMPORARY DEMOGRAPHIC SITUATION
Authors: Manakina E A , Medvedeva O V
Published: October 2016

Modern demographic situation determines the need for optimization of organizational technologies in nursing regional maternity hospitals, which will allow more efficient distribution and use of human resources, to co-ordinate services and facilities to meet the requirements of the current situation.
DISTRIBUTION AND DYNAMICS OF CHEMICAL ELEMENTS IN PINE ECOSYSTEMS MESHCHERSKY WOODLAND
Authors: Podol S R , Popova Z I
Published: October 2016

Determined the chemical composition of the main tree species, understory and ground cover of pine plant communities Meshchera. These areas belong to the National Park and area natural geochemical sample "background", because quite removed from sources of industrial pollution. However, the pine forest biogeocenoses formed on mineralogiccally a poor substrate, under conditions of pronounced deficit of nutrients. In these conditions, a large role is played by the position of phytocenoses in the microrelief and the groundwater level. The features of the absorption and accumulation by plants of calcium, magnesium, iron, manganese, zinc and copper. Revealed a pronounced deficiency of calcium, magnesium and copper in coniferous species with a relative accumulation of vegetation iron and manganese. It is established that intensive extraction of chemical elements from the soil and rapid treatment in the plant-soil system ensures the stable operation of biogeocenoses pine forests with initially low availability of nutrients.
HISTORY OF DENTAL CARE IN THE RYAZAN REGION
Authors: Peshkov V A
Published: October 2016

The article from the late 19th century to the present days analyzed the history of dental care of Ryazan region and the emergence of the first dental clinics. History of formation of dental care in the Ryazan region show great work of dentists in improving the provision of medical care at all stages of development of health care of the Russian Federation.
ATROPHIC CHANGES OF THE CORPUS CALLOSUM IN MULTIPLE SCLEROSIS
Authors: Dzhaparalieva N T , Lorina L V
Published: October 2016

The changes in the parameters of the corpus callosum, depending on the type of flow, duration of disease and degree disability in multiple saclerosis. Most sensitive with respect to the investigated indices proved trunk of the corpus callosum, to a lesser extent the knee. For the same period of the disease atrophy of the corpus callosum in patients with primary progressive course of multiple sclerosis is much more pronounced than in other types of flow. Reducing the size of the corpus callosum in progressive types of flow suggests ongoing secondary degeneration of fibers.
INFLUENCE OF RHINOSURGERY ON THE COURSE OF OBSTRUCTIVE APNEA SYNDROME
Authors: Tardov M V , Kunelskaya N L , Turovsky A B , Ivoylov A Y , Klyasov A V , Zarapkin G Y , Artemev M E , Arhangelskaya I I , Zaoeva Z O , Kondrashina V V
Published: October 2016

Purpose of this open study was the evaluation of rhinosurgery effect on the course of obstructive apnea syndrome (OSA). 25 patients 25-60 years old with nasal obstruction and OSA were examined: neurologic, otorhynolaryngologic studies and cardiopulmonary monitoring were conducted before and 3-4 months after nasal surgery. 50% or more decline of sleep apnea index (SAI) was observed in 6 (24%) persons, in other 6 (24%) persons SAI has grown up 50% or more, no significant difference was shown in 13 patients (52%). No correlation of SAI shift after surgical treatment with physical, anamnestic and respiratory data were demonstrated. Nasal surgery leads to positive results referring to pharyngeal obstruction not more than in 24% of cases. Today we have no proved predictors of high nasal correction effect on the severity of OSA.
ADENOCARCINOMA OF MINOR DUODENAL PAPILLA
Authors: Shabunin A V , Paklina O V , Setdikova G R , Tavobilov M M , Grekov D N , Gordienko E N
Published: October 2016

The article presents a rare clinical case of adenocarcinoma of the minor duodenal papilla at man - 51 years old. This was the first case in our practice since 2002 among the 310 pancreaticoduodenal complexes with varied pathologies studied. Histologically, the tumor is similar to pancreatic ductal adenocarcinoma and ampullar carcinoma (pancreatobiliary type). To avoid diagnostic errors of gross examination, it is highly important to follow the step-by-step algorithm of dissection.
QUALITY OF LIFE ASSESSMENT USING A QUESTIONNAIRES IN PATIENTS WITH VENOUS DISEASE OF LOWER EXTREMITIES
Authors: Agapov A B
Published: October 2016

The article presents the modern concept of the term "quality of life" and the methodology of his research with the help of general and specific questionnaires for patients with venous disease, including venous thrombosis. Analysis of the quality of life is essential to evaluate the effectiveness of treatment and in conjunction with objective data makes it possible to obtain comprehensive information about the influence of a drug or surgical treatment for the patient in a remote period.
THE ANALYSIS OF CONTEMPORARY METHODS OF OCCLUSION ESTIMATION AND REGISTRATION ON THE STAGE OF ORTHOPEDIC DENTISTRY TREATMENT
Authors: Mitin N E , Nabatchikova L P , Vasilyeva T A
Published: October 2016

A survey of literature on the subject of occlusion diagnostic methods on the stage of orthopedic dentistry treatment is represented. Different contemporary methods of occlusion registration and analysis are described. The essential advantages and drawbacks of every referred method are specified.
IMMUNOHISTOCHEMICAL ANALYSIS OF LIVER TISSUE IN SPONTANEOUS REGENERATION IN THE RECOVERY PERIOD AFTER EXPERIMENTAL FIBROSIS
Authors: Dvoryashina I A , Velikorodnaya Yu I , Pocheptsov A Ya , Zagrebin V L
Published: October 2016

We investigated the process of spontaneous liver regeneration after chemically induced experimental fibrosis. The obtained data about activity of some liver metalloproteinases, shown important role of each metalloproteinases at different stages of liver recovery.
SOME INDICATORS OF QUALITY OF LIFE OF PATIENTS WITH HIV INFECTION IN CONDITIONS OF THE REPUBLIC OF TAJIKISTAN
Authors: Tursunov R A
Published: October 2016

This article presents an analysis of some indicators of the quality of life (QOL) in 100 HIV-infected patients living in the Republic of Tajikistan. The evaluation was conducted using the SF-36 questionnaire. The age of respondents ranged from 17 to 56 years, of which 61,7% were men and 38,3% - women. Comparative analysis QOL revealed in HIV-infected women's higher rates of psychosocial component scale SF-36 than men living with HIV. Despite this availability of the problem is a significant factor that reduces the level of QOL of people living with HIV (PLHIV). In patients from the study group the decrease QOL was due to statistically low levels (p0,05) on the scale of the psychosocial aspects - social (51,4 points - in the study group, 76,1 points - in the control), and role functioning due to emotional condition (56,9 and 77,2 points, respectively), general health (49,3 and 63,4 points), mental health (51,2 and 70,1 points), as well as the vital activity (49,6 and 63,4 points). QOL of PLHIV indicators are set, such as general health, family, emotional sphere, social contacts, vital activity, level of education, level of stigma and discrimination, as well as access to health services.
IMPACT MEDICAL-SOCIAL FACTORS AND BEHAVIOR OF PATIENT WITH ECTOPIC PREGNANCY ON THE DURATION OF HOSPITAL STAY
Authors: Cherkasov S N , Kurnosikov M S
Published: October 2016

The study deals to the problems of planning of hospital care in ectopic pregnancy. It is shown that the importance of the factors based on medical and social characteristics of the patient, determined by the ability of management influence, by forming a comprehensive prevention programs with the goal of reducing the probability of prolonged hospital stay. The use of this approach at the level of the municipality substantially increases the economic and social efficiency.
AGE-RELATED AND STRESS-INDUCED PROTEINOPATHY OF CEREBRAL NEURONS IN RATS
Authors: Zagrebin V L , Antoshkin O N , Fedorova O V , Terentiev A V , Sargsyan S A , Egorova A S
Published: October 2016

A study of morphological and functional changes in neurons and glial cells of the cerebral cortex of white rats at the stages of aging and stress-induced neurodegeneration under experiment was investigated. It was found that the age-related neurodegenerative changes in somatosensory cortex neurons of white rats at the age of 30 months are characterized with pronounced signs of proteoinopathy and developing of apoptosis, which is enhanced by exposure to stress factors in clear violation of protein metabolism in the form of accumulation of intra- and extracellular amyloid.
THE SYSTEM OF PROPHYLAXIS OF NONINFECTIOUS DISEASES AT BUDGETARY SPHERE WORKERS
Authors: Vvedensky A I
Published: October 2016

In the article the characteristic of a structure of arrangements about the formation of healthy lifestyle and prophylaxis of noninfectious diseases is given. The main content of complex purpose programs about prophylaxis of noninfectious diseases at a level of Russian Federation subjects is opened. The algorithm of forming healthy lifestyle is performed, and functional reserving of basic elements of medical prophylaxis as well.
METHODOLOGICAL AND ORGANIZATIONAL BASES OF DEVELOPMENT OF PUBLIC HEALTH AS A PRIORITY SUBSYSTEM OF SOCIAL AND ECONOMIC SPHERE OF REGION
Authors: Pachgin I V , Kicha D I
Published: October 2016

Methodological and methodical bases of creation of medico-social of insurance cluster are considered by in the article. The integration action of sectors of the economy and social sphere to improve the health of workers of the economically active working age (workers of metallurgical and mining enterprises) is substantiated. The region is considered as an organized and structured socio-economic system. The development of this system is based on the optimal linkages between priority sectors.
EPITHELIAL AND STROMAL COMPONENTS IN DUCTAL BREAST CANCER
Authors: Mnikhovich M V
Published: October 2016

Currently, most of the scientific work is focused on the study of epithelial-stromal relations play an important role in the progression of epithelial tumors towards dedifferentiated phenotype. The aim of our research - the study of morphological properties of anaplastic tumor sites and surrounding stroma of ductal breast cancer. Epithelial-stromal interactions in ductal breast cancer cause its aggressive biological behavior, resistance to chemotherapy and varying depending on the survival of tumor differentiation. Heterogeneity is manifested in the ductal carcinoma anaplastic appearance (sarcomatoid) component, which traced the ability of epithelial tumor cells acquire the properties of mesenchymal cells do not require the stroma and have an aggressive malignant potential impact on survival of patients.
Severity of hepatic dysfunction and its correction in the complex treatment of acute intestinal obstruction
Authors: Amahanov A K , Fedoseev A V , Budarev V N , Allniasi A Edin , Taha H Dib
Published: October 2016

The article describes the role that could play a hepatoprotective therapy in the treatment of patients with acute intestinal obstruction. The study involved 128 patients with mechanical acute intestinal obstruction, accompanied by the syndrome of enteral insufficiency. Hepatoprotective drugs have been added in the scheme of treatment. It has been proven beneficial therapeutic effect of this measure on the dynamics of the development of hepatorenal syndrome, syndrome of enteral insufficiency.
Experimental models of acute liver failure
Authors: Rudakov V S , Voskanyan S E , Eremin I I , Deev R V
Published: October 2016

Acute liver failure is a result of massive hepatic necrosis, accompanied by development of hepatic encephalopathy and can cause multiple organ failure with a high risk of death. Treatment of severe acute liver failure remains the most difficult clinical problem. Reproducible experimental model is required to develop new drugs and strategies of treatment of this pathology. Animal model must be close to clinical practice. This review critically examines many of the models described in the literature and discusses the surrounding issues.
Association between the activity of enzyme CYP3A4 and profile of efficacy and safety of haloperidol in patiens with alcohol addiction
Authors: Zastrozhin M S , Smirnov V V , Sychev D A , Savchenko L M , Bryun E A , Guschina Yu Sh , Esakova A P , Galaktionova T E
Published: October 2016

In case of patients with alcohol addiction haloperidol is used to control the exacerbation of the addiction, but the empirical dose selection of haloperidol often results in adverse side effects. Microsomal isozyme cytochrome P450 3A4, the activity of which has wide variability, takes part in biotransformation of haloperidol. The study involved 20 men with alcohol addiction. The efficacy and safety of haloperidol was evaluated by international psychometric scales. The activity of CYP3A4 was evaluated by determination endogenous substrate of this isoenzyme and its metabolite in urine - (the ratio of 6-beta-hydrocortizol/corizol). The study revealed a statistically significant patterns between the activity of CYP3A4 and the efficacy and safety of haloperidol.
Clinical and suicidological description alcohol dependendent patients with comorbidity borderline personality disorder
Authors: Shitov E A , Merinov A V , Shustov D I , Fedotov I A
Published: October 2016

We consider the problem of combination of mental disorders and addiction disorders (comorbidity). There was a brief overview of the relevance of the problem. We described the available literature data on the comorbidity of borderline personality disorder and disorders of addiction. We studied patients who showed a combination of borderline personality disorder and alcohol dependence. Suicidological and clinical characteristics of this group of patients was made by us. We made the conclusions regarding the severity of the course of alcohol dependence in the background of borderline personality disorder.
Outcomes and formation of comorbidity among infants born with very low and extremely low birth weight
Authors: Dmitriev A V , Blohova E E , Gudkov R A , Fedin N V
Published: October 2016

This article surveys the physical and motor development of 134 children aged 1 year born with very low (VLBW) and extremely low birth weight (ELBW). At follow-up, 17,5% and 47,1% infants were below the 10th percentile for length and weight at 12 months corrected age. 70,5% ELBW infants and only 22,4% VLBW infants have neurodevelopmental delay. ELBW babies have higher levels of comorbidity comparing VLBW babies and risk of comorbidity correlate negatively with physical development.
Some features of the white line of the abdomen, as the harbingers of post-operative hernia
Authors: Fedoseev A V , Muraviev S J , Budarev V N , Inyutin A S , Zatsarinnyi V V
Published: October 2016

The article discusses the study of morpho-functional features of the white line of the abdomen and their role in the etiology of postoperative ventral hernias. For this purpose, the analysis of available literature sources over the past 13 years was performed. Our own research was also represented. It was determined the influence of different factors such as sex, shape of the abdomen, the morpho-functional structure of the white line on the incidence of postoperative ventral hernias.
Social characteristics and quality of life of patients seeking surgical care dental
Authors: Peshkov M V , Gurevich K G
Published: October 2016

Social factors, as well as health have a direct impact on the indicator of quality of life. Since the efficiency of the medical service affects the quality of life of patients, the physician must take into account social factors in their work. Quality of life in dentistry based on filling special questionnaires. The most acceptable and commonly used is the OHIP-14 questionnaire. In the literature there are few studies devoted to the study of quality of life of patients dental surgical and social characteristics, and in our country is completely absent.
The chewing efficiency determining method based on application of original computer program using multivariate data analysis
Authors: Mitin N E , Vasilyeva T A , Vasilyev E V
Published: October 2016

The paper presents a methodology for determining the chewing efficiency by using the developed computer program, created on the basis of multivariate data analysis. This method allows to explore the chewing efficiency by means of occlusion scans obtained on wax. The accuracy of the chewing efficiency estimation using the computer program is compared with modern functional chewing probes.
Special features of protocol of enhanced recovery after surgery in colorectal patients
Authors: Khubezov D A , Rodimov S V , Puchkov D K , Lukanin R V , Ydina E A
Published: October 2016

In a review article describes general positions and the scientific justification of using of protocol of enhanced recovery after surgery in patients who underwent resection of the colon. Also discussed in detail different views and results of randomised studies of using this protocol and all of the most "controversial" elements such as mechanical preparation of the bowel, abdominal drainage, the principles of controlled infusion therapy, and others. All findings allow us to evaluate the result of using of this protocol in colorectal patients.
The role of pathoanatomical departments in improving medical education (literature review)
Authors: Nikulina N N
Published: October 2016

The article discusses the relevance of formation and improvement of clinical thinking in the primary and subsequent postgraduate continuous medical education of clinicians. The article provides the rationale that the post-mortem examination remains the "gold standard" of post-mortem diagnostics, and the frequency and relevance of intravital pathoanatomical diagnostics (biopsies) only increases every year. Examines diagnostic, expert and methodological functions of the pathology service in modern medical education and health care in General.
The urgency of the problem of adhesions in the pelvis, its consequences and the role of undifferentiated connective tissue dysplasia in its development
Authors: Repina N B , Ben Salha M
Published: October 2016

This article describes the prevalence, diagnosis of chronic pelvic pain syndrome (CPPS) and negatively reflect on the quality of life of patients. Pelvic peritoneal adhesions are one of the most important causes of CPPS (17%). The mechanism of occurrence of adhesions in the abdominal cavity and peritoneal reaction to the action of various stimuli is not completely disclosed but the tendency to the formation of adhesions, is a variant form of undifferentiated connective tissue dysplasia.
Reciprocal reactions to different amounts of increased breathihg resistance
Authors: Byalovsky Yu Yu
Published: October 2016

Objective: to study the role of the components of the stress-realizing and stress-limiting body systems at adaptation to different values breathing resistance. Materials and Methods: The study was conducted on healthy individuals (126 men), aged 18 to 38 years old of both sexes. Inspiratory breathing applied resistive load value of 20, 40 and 60%Pmmax. We measured the performance of hemostasis, immunity, oxidative activity, stress hormones. Results: Inspiratory load 40%Pmmax leads to activation of the anticoagulating mechanisms, increase antioxidant activity, stress-limiting effects and immunosuppressive changes; load 60%Pmmax caused opposite effects. Conclusions: The increased breathing resistance 40%Pmmax activates the stress-limiting systems; resistive load 60%Pmmax causes activation reciprocally organized stress-implement systems.
Medical and demographic aspects of public health population of Sterlitamak city, Republic of Bashkortostan
Authors: Balberova O V , Murzagalin T Sh , Nikitina O A
Published: October 2016

Population health status of Sterlitamak city has its own peculiarities, which requires study and development targeted interventions on the priority issues of regional healthcare. In addition, it is advisable to use the capacity of the service dealing with the influence of various factors on the health of the population, taking into account characteristics of the region in order to study and contain the morbidity in the territory.
Comparative study of non-complicated painful shoulder syndrome treatment by glucocorticoid and anesthetic combination and the factor of interleukin 1 receptor inhibition (Orthokine)
Authors: Lebedev N N , Khalatov V S , Shikhmetov A N , Shvetzov G I , Rozhkova T I
Published: October 2016

The aim of the study was to compare treatment of non-complicated painful shoulder syndrome (PSS) by injections of combines anesthetic Procain (0,5-10% Novocain) and glucocorticoid Betamethasone (Dyprospan 1 ml) (DN) and by injection of autologous conditioned serum with high content of interleukin 1 Pa receptor antagonist (Orthokine, OK). We studied proximate results within 6 months. Thirty three patients (18 males and 15 females) were included in OK group within age range 35-80 years. Seventy patients were enrolled in DN group (40 males and 30 females) within age range 35-72 years without endocrine disorders. All patients were assessed by visual analogous pain score (0-10), underwent physical exam with palpation of painful points and examination of shoulder biomechanics by the original PSS severity scale, X-ray and magnetic resonance imaging of painful shoulder joints. Injections were performed in the maximally painful areas with inflammatory changes verified by MRI. Each patient of OK group underwent 6 injections with 4-6 day interval. The same interval was for DN group, the number of injections were 3-5. In the OK group alleviation of pain and shoulder biomechanics occurred only after 3-4 injections with gradual improvement, whereas DN injections relieved pain and improved shoulder mobility already after 1-2 injections without further enhancement of the effect. Side effects were encountered in 70% of DN group patients, in 10% of them treatment was withdrawn. No side effects or allergic reactions were seen in OK group. The effect of OK occurs later, is less prominent, but tends to increase to compare with DN injections, however, OK is more safe and tolerable and may be the technique of choice in patients with PSS and endocrine disorders.
Recurrent varices after surgery
Authors: Sadriev O N , Kalmykov E L , Gaibov A D , Inoyatov M S
Published: October 2016

The aim - analysis of causes and treatment of recurrent varices after surgery. Results of the study. At receipt of chronic venous insufficiency (CVI) of C2 was noted in 22 (38.5 %%) C3 26 (45.6%), and C4 in 9 (15.7%) cases. The vast majority of patients (n = 45 (78.9%)) were operated under general surgery departments of district general surgeons. Neoangi-ogenesis groin noted in 7 (12.2%) cases. In 8 (14%) cases in patients with primary operations were removed only varicose tributaries of the great saphenous vein trunk. Of the 57 patients, 6 (10.5%) had not revealed the presence of a remote trunk great saphenous vein in the thigh, and 4 (7%) cases marked by recanalization of the great saphenous vein trunk at the hip after EVLT. In 3 (5.3%) cases were identified long stump of the small saphenous vein. In 6 (10.5%) cases not removed at the trunk BPV tibia. In 3 (5.3%) cases were identified long stump of the small saphenous vein. In the remaining 23 cases noted the presence of varicose veins changed hypodermic pools large and small saphenous veins (GSV, SSV) (they are recorded in 9 cases residual varicose veins). Of the 57 patients, surgical treatment performed in 54 observations, surgical tactics depended on the location and cause of relapse. In 10 cases, resection of the stump of GSV/SSV and ligation of its tributaries. Just 10 patients made stripping the GSV trunk at the hip. In 14 patients we performed EVLT of trunk of the great saphenous vein and miniphlebectomy of tributaries. Conclusions. RVD in most cases is caused by tactical and technical errors after the initial operation, as well as the progression of the varicose veins and requires a differentiated approach in the treatment based on the study of venous hemodynamics using duplex scanning.
Classification criteria of chronic pancreatitis
Authors: Tarasenko S V , Rakhmaev T S , Peskov O D , Kopeikin A A , Zaytsev O V , Sokolova S N , Bakonina I V , Natalskiy A A , Bogomolov A Y , Kadykova O A
Published: October 2016

This is the analysis of the most widespread classification of chronical pancreatitis and the results of retrospective distribution of 120 patients. In our article the review of the main actual classifications of chronic pancreatitis is executed. Our own classification is presented. The authors suppose that the volume of the surgical intervention in most cases is determined by morphological alterations in the pancreas. The most important changes are affections of pancreas parenchyma (criterion “P”), large cavities (criterion “C”), and widening of Wirsung’s duct (criterion “H”). Such king of morphology is evidence for transferring a patient to a surgical department. Its assessment together with clinical signs determines expediency of operation. The method of surgical treatment depends on the localization and the combination of morphological changes. Existence of the positive criterion "Р" in combination with a constant or recidivous pain syndrome demands performance of a resection of a head of a pancreas. Existence of a large extrapancreatic cyst assumes preliminary mini-invasive treatment with the subsequent assessment of a condition of a parenchyma and expressiveness of clinic of pancreatitis. Expansion of the main pancreatic duct - the criterion of "H" refers to the need for wide opening duct during resection of the pancreas. So, the choice of surgical technique in a particular clinical situation depends on many factors, but in most cases, the amount of operation is determined by morphological changes in the pancreas. We created the classification considering morphological criteria. Efficiency of this scheme confirms the analysis of the remote results of surgical treatment of patients with chronic pancreatitis.
Influence of enteral insufficiency on the acute pancreatitis development
Authors: Taha H D , Fedoseev A V , Muraviev S J , Budarev V N , Inyutin A S
Published: October 2016

Improvement of acute pancreatitis treatment requires a detailed study of the accompanying pathological changes in the body. In our study, we carried out the analysis of a number of parameters characterizing enteral insufficiency syndrome accompanying acute pancreatitis. The relationship between the severity of enteral insufficiency syndrome and endogenous intoxication, immune deficiency was identified.
Case of successful diagnosis and surgical treatment of aneurysms with atypical origin splenic artery
Authors: Gulmuradov T G , Avgonov U M , Sadriev O N , Shoev F S
Published: October 2016

The article describes a case of successful diagnosis and surgical treatment of patients with aneurysm of the splenic artery (ASA) with atypical origin from the abdominal aorta. For a long time, ASA had symptoms like chronic pancreatitis. Due to the discharge of an atypical splenic artery computed tomography of its aneurysmal expansion was evaluated as an aneurysm of the celiac trunk. A decisive role in the topical diagnosis of aneurysm played angiography of the abdominal aorta and its visceral branches. The blood circulation of the spleen was compensated and authors preferred to preserve spleen with resection of the aneurysm. In the immediate postoperative period, signs of splenic ischemia and other complications are not logged in.
Possibilities of radiological methods in diagnostics of adrenal tumors
Authors: Sadriev O N , Gaibov A D , Gulmuradov T G , Anvarova Sh S
Published: October 2016

The aim - to assess the possibilities of ultrasound and computed tomography in the diagnosis and differential diagnosis of adrenal tumors. Results of the study. The paper analyzes the possibilities of ultrasound (US) and computed tomography (CT) in the diagnosis of various nosological forms of adrenal tumors in 54 patients. As according to US and CT the large size of tumors were characterized to pheochromocytoma (PCHC) (78,5 ± 5,3 - 75,6 ± 6,3 mm), small and medium - to corticosteroma (CS) (45,2 ± 2 6 - 45,6 ± 4,3 mm) and aldosteroma (AS) (46,2 ± 7,1 - 45,9 ± 5,4 mm). Adrenocortical tumors were characterized mostly by round or oval shape, to pheochromocytoma in most cases - wrong rounded shape. These morphometric parameters like irregular contours, heterogeneity of structure and presence of inclusions in the structure of tumor was characterized mainly for pheochromocytoma, whereas tumors of the adrenal cortex these signs were absent. Statistically significant differences in density of PCHC (+ 24,2 ± 2,3 UH), CS (+ 13,4 ± 0,3 UH) and the AS (+ 5,1 ± 0,2 UH) in native mode and contrasting (PCHS - + 41,5 ± 6,1 UH; CS - 18,6 ± 0,9 UH; AS - + 12,1 ± 0,4 UH), as well as the time difference of contrast washout (in pheochromocytoma 14,7 ± 0 5 min. at corticosteroma 8,7 ± 0.4 min., and at aldosteroma 6,2 ± 0,4 min.). Due to the small size of the tumor, obesity and meteorism ultrasound was not informative in 3 cases. In all cases, CT permit to determine the location of the tumor definitely and to differentiate their various nosological forms significantly. Conclusion. Ultrasound and CT in the detection and differentiation of adrenal tumors showed high sensitivity and specificity, and the comparison of different clinical signs of adrenal tumors with the revealed CT signs can more accurately suggest adrenal tumor morphology and to be clinically significant in the choice of further treatment approach.