bluuebunny/crossref_metadata_2025 huggingface dataset:
Some Observations on the Chemotherapy and the Prevalence of Drug-Resistant Bacilli in Untreated Patients with Pulmonary Tuberculosis
Authors: Hong Sung Moon , Shin Yung Kee , Lee Chan S.
Published: March 2022

We observed the roentgenological & bacteriological results of anti-tuberculous chemotherapy among the 86 of newly diagnosed, previously untreated patients with pulmonary tuberculosis who had visited to our clinic since September 1958 to April 1960.In addition, we also studied the prevalence of bacillary resistant to S.M., P.A.S. and I.N.H. among them.The results we obtained are as follows:1) 79 % of them showed roentgenological improvement during the course of antituberculous chemotherapy.(Marked Imp: 22%, Mod. Imp.: 26 %, Slight Imp.: 31%) 2) Sputum negative conversion was seen in 89%, and most of them converted within 4 months of chemotherapy. It is believed also that an adequate bed rest still played an important role in the treatment of pulmonary tuberculosis.3) Persistent positive sputum was seen in 11% and most of them had cavitary lesions, longer duration until diagnosed and irregular treatment.4) Sensitivity tests to S.M. P.A.S. and I.N.H. were under-taken oh 69 positive culture The rates of primary drug-resistant were as follows; S .M. (10r.) 13%, P.A.S. (10r.) 4%, I.N.H.(5r.) 13%.
Perspectives on the urological care in Parkinson’s disease patients
Authors: Moussa Mohamad , Abou Chakra Mohamad , Papatsoris Athanasios G. , Dellis Athanasios , Dabboucy Baraa , Peyromaure Michael , Barry Delongchamps Nicolas , Bailly Hugo , Duquesne Igor
Published: March 2022

Parkinson's disease (PD) is recognized as the most common neurodegenerative disorder after Alzheimer's disease. Lower urinary tract symptoms are common in patients with PD, either storage symptoms (overactive bladder symptoms or OAB) or voiding symptoms. The most important diagnostic clues for urinary disturbances are provided by the patient's medical history. Urodynamic evaluation allows the determination of the underlying bladder disorder and may help in the treatment selection. Pharmacologic interventions especially anticholinergic medications are the first-line option for treating OAB in patients with PD. However, it is important to balance the therapeutic benefits of these drugs with their potential adverse effects. Intra-detrusor Botulinum toxin injections, electrical stimulation were also used to treat OAB in those patients with variable efficacy. Mirabegron is a β3-agonist that can also be used for OAB with superior tolerability to anticholinergics. Desmopressin is effective for the management of nocturnal polyuria which has been reported to be common in PD. Deep brain stimulation (DBS) surgery is effective in improving urinary functions in PD patients. Sexual dysfunction is also common in PD. Phosphodiesterase type 5 inhibitors are first-line therapies for PD-associated erectile dysfunction (ED). Treatment with apomorphine sublingually is another therapeutic option for PD patients with ED. Pathologic hypersexuality has occasionally been reported in patients with PD, linked to dopaminergic agonists. The first step of treatment of hypersexuality consists of reducing the dose of dopaminergic medication. This review summarizes the epidemiology, pathogenesis, risk factors, genetic, clinical manifestations, diagnostic test, and management of PD. Lastly, the urologic outcomes and therapies are reviewed.
SARS-CoV-2 infection rates after different vaccination schemes
Authors: Toprak Oya Baydar , Ozen Sennur , Ozturk Berker , Ozturk Burcu , Ozturk Ebru , Kitapci Mehmet , Kokturk Nurdan
Published: March 2022

Objective:

To identify effects of various nationwide vaccination protocols on the evolution of new SARS-CoV-2 infections among adult population and to evaluate the safety of mRNA (BioNTech/ Pfizer) vaccine.

Methods:

Totally 10 735 adult volunteers that received at least one dose of BioNTech/Pfizer or triple doses of CoronaVac participated in this cross-sectional-online survey between 1 and 10 September 2021. The information was collected covering a 5-month period from April 2021 to September 2021. Information about people who were vaccinated with only single and double dose CoronaVac were not included in this study.

Results:

At least one side effect after single and double dose of BioNTech/Pfizer and triple doses of CoronaVac were observed in 42.1%, 42.5% and 10.9%, respectively. The most common side effects were shoulder/arm pain, weakness/fatigue, muscle/joint pain and headache. The side effects were the most frequent in single BioNTech/Pfizer, while it was the least in triple CoronaVac. The rate of positive PCR tests before vaccination was 17.6%, and decreased to 3.0% after vaccination. The rates of positive SARS CoV-2-PCR were 18.8%, 3.5%, 3.1%, 0.5% and 4.6% in single BioNTech/Pfizer, double BioNTech/Pfizer, double CoronaVac+single BioNTech/Pfizer, double CoronaVac+double BioNTech/Pfizer and triple CoronaVac, respectively. While 1.8% of PCR positive COVID-19 cases needed intensive unit care in the pre-vaccination period, intensive care unit was required in 0%, 1.5%, 2.4%, 0% and 4.2% after single BioNTech/ Pfizer, double BioNTech/Pfizer, double CoronaVac+single BioNTech/ Pfizer, double CoronaVac+double BioNTech/Pfizer and triple CoronaVac, respectively. Reinfection rate after vaccination was 0.4%.

Conclusions:

The rarity of COVID-19 infection after vaccination suggests that efficacy of vaccines is maintained. On the other hand, the data underscore the critical importance of continued public health mitigation.
Evaluation of Plasma Fibrinogen Levels before and after Coronary Artery Bypass Graft Surgery and Its Association with the Need for Blood Products
Authors: Honarmand Azim , Bagheri Keivan , Hoghooghy Alireza , Rezaei Kazem
Published: March 2022

Background:

The present study investigated the plasma level of fibrinogen before and after removing the pump in coronary artery bypass graft (CABG) surgery and its relationship with the need for blood products.

Materials and Methods:

The present study was performed on 60 patients who were candidates for CABG surgery. The fibrinogen level of these patients was assessed and recorded before surgery and immediately after removing the pump. In addition, their hemoglobin level was recorded before the operation and 2 h after. In addition, the number and type of blood products transfusion were recorded intraoperatively and postoperatively and also at the intensive care unit.

Results:

Patients’ fibrinogen level after removing the pump with the mean of 130.53 ± 122.01 mg/dl decreased significantly compared to before surgery with the mean of mg/dl 224.95 ± 132.88 mg/dl (P < 0.001). In addition, the prognostic value of fibrinogen after removing the pump in determining the postoperative need of blood transfusion showed that the cut-off value of fibrinogen was < 196 mg/dl with a sensitivity of 16.82% and specificity of 80%, but it was not statistically significant (area under the curve [95% confidence interval]: 0.519 [0.350–0.689]; P = 0.825).

Conclusion:

According to the results of the present study, due to significant changes in fibrinogen levels after removing the pump compared to preoperation, it seems that this factor can play an important role in prognosis of the need to postoperative blood transfusion, although the prognostic value and the critical point mentioned in our study was not significant and it is required to do further studies.
A 10-case series of Merkel cell carcinoma in tropical Taiwan
Authors: Su Chia-Jui , Lan Jui , Lee Chih-Hung
Published: March 2022

Background:

There are limited data discussing Merkel cell carcinoma (MCC) clinicopathological characteristics in Asian patients. Furthermore, the association between two key pathogenic factors, ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV), remained unclear.

Objectives:

This study aimed to study the clinicopathological features in Taiwanese patients and to discuss the interaction between MCPyV infection and UV radiation-induced oxidative stress.

Methods:

We retrospectively reviewed the clinical features, pathological morphology, treatment, and outcomes of ten patients with histologically proved MCC. Eight specimens were tested for MCPyV large T-antigen. Five specimens with positive MCPyV large T-antigen were tested for 8-hydroxy-2-deoxyguanosine (8-OHdG).

Results:

Eight (80%) patients were male, and the median age at diagnosis was 81 years. The most common primary tumor site was extremities (8 patients, 80%), with the rest located on the head and neck region (2 patients, 20%). Intermediate type was the most common pathology subtype, with more than 70% showing reactivity to MCPyV large T-antigen. Four tumors out of 5 (80%) showed 8-OHdG positivity.

Conclusion:

The study showed similar demographics with previous studies in western countries but had different tumor location frequencies when compared with northeast Asia. The high frequency of UV signature oxidative stress marker, 8-OHdG in MCPyV large T-antigen-positive tumors may indicate the correlation between UV radiation and MCPyV infection. Further studies with larger numbers of patients may be required to verify its significance.
A novel nomogram based on DNA damage response-related gene expression in patients with O-6-methylguanine-DNA methyltransferase unmethylated glioblastoma receiving temozolomide chemotherapy
Authors: Wang Rong , Peng Yingpeng , Wei Wei , Zhou Yuling , Li Xiaonan , Xia Yunfei , Liu Zhigang
Published: March 2022

Background

-

and

-

Aim:

Glioblastoma (GBM) is the most lethal primary brain tumor. Patients with unmethylated O-6-methylguanine-DNA methyltransferase (MGMT) promoter have higher MGMT expression, are less sensitive to temozolomide (TMZ), and are linked to poor prognosis. The aim of this study was to identify patients from this population with a better prognosis, explore the molecular mechanism, and provide a theoretical basis for the formulation of treatment strategies.

Materials

-

and

-

Methods:

Prognostic genes involved in the DNA damage response (DDR) pathway were screened, and the risk score of each GBM patient undergoing TMZ chemotherapy from The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) database was calculated. A comprehensive prognostic nomogram model was constructed by combining the risk score and other clinical features.

Results:

Two DDR-related genes (replication factor C subunit 2 [RFC2] and methyl-CpG binding domain 4, DNA glycosylase [MBD4]) were identified as having a prognostic value in GBM patients with unmethylated MGMT promoter. Patients were classified into high- and low-risk groups using the risk score based on the expression of these two genes. The median overall survival of patients in the low-risk group was significantly longer than that recorded in the high-risk group in the TCGA cohort (15.95 vs. 11.90 months, respectively, P = 0.027) and CGGA cohort (25.90 vs. 11.87 months, respectively, P = 0.0082). The expression of those two genes was confirmed in tissue samples, and the risk scoring model showed that their prognostic value was independent of other clinical characteristics (P = 0.032), such as age. A final nomogram model was constructed, and its good performance was validated (concordance-index = 0.6656).

Conclusions:

A comprehensive prognostic model for patients with MGMT unmethylated GBM receiving TMZ chemotherapy was constructed using RFC2 and MBD4 gene expression, age, sex, and isocitrate dehydrogenase. The model showed good performance.
Positive Correlation of Oestradiol Level on Trigger Day with the Secretion Level of Endometrial Kisspeptin and Leukaemia Inhibitory Factor in the Mid-Luteal Stimulated Cycle
Authors: Polim Arie Adrianus , Abdullah Nusratuddin , Hatta Mochammad , Natzir Rosdiana , Soebijanto Soegiharto , Hutomo Caroline , Pradana Aryando , Rambei Reino
Published: March 2022

Background:

Kisspeptin plays a role in the oestradiol negative-feedback regulation of GnRH as well as gonadotropin. In addition, kisspeptin has been postulated to induce the production of an important cytokine called leukaemia inhibitory factor (LIF).

Aims:

This study aims to investigate the correlation between varying oestradiol levels measured on trigger day of the ovarian stimulation and the mRNA expression level of endometrial kisspeptin and LIF.

Study Setting and Design:

Prospective cross-sectional study took place in Morula IVF Jakarta clinic.

Materials and Methods:

A total of 43 infertile couples underwent an in-vitro fertilization (IVF) program. Subjects were grouped based on oestradiol levels as follows: group A ([≧ 3000 pg/mL, n = 15], group B [2000–2999 pg/mL, n = 14], group C [<2000 pg/mL, n = 14]).

Statistical Analysis Used:

ANOVA test was utilised to compare the expression of kisspeptin and LIF among study groups while Pearson correlation was used to identify the correlation between variables.

Results:

A significantly higher mRNA expression of both Kisspeptin and LIF was found in group A than in groups B and C (P < 0.001). The mRNA expression of kisspeptin and LIF correlated positively with the oestradiol level (r = 0.638, P < 0.001 and r = 0.634, P < 0.001, respectively). Moreover, a strong association between Kisspeptin and LIF expression was also detected (r = 0.700, P < 0.001).

Conclusions:

mRNA expression of kisspeptin and LIF was significantly different according to the oestradiol levels in the study groups. Increased oestradiol level was shown to elevate the expression of endometrial kisspeptin and LIF in women undergoing the IVF programme.
Embryo/Fetus Doses from 18F-Fludeoxyglucose Radiopharmaceutical in Positron Emission Tomography/ Computed Tomography
Authors: Işıkçı Nazenin İpek , Demir Mustafa
Published: March 2022

Aim:

The embryo/fetus may be accidentally exposed to ionizing radiation. The aim of this study is to calculate embryo/fetus doses in pregnant women who underwent F-18 fludeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan.

Materials and Methods:

Between June 2015 and June 2021, 15 pregnant women underwent F-18 FDG PET/CT applied to the Genetic Research Center (GETAM). The OLINDA/EXM package program was used for internal radiation dosimetry according to the Medical Internal Radiation Dose scheme. FetDose V4 computer software was used to compute the embryo/fetus absorbed dose from CT scan.

Results:

The amount of the injected F-18 FDG activity to patients varied between 333 and 555 MBq. The mean embryo/fetal dose from F-18 FDG was 7.2 ± 2.8 mGy. In addition, the CT component dose to the embryo/fetus dose ranged from 8.5 to 16 mGy with a mean of 12.14 ± 2.05.

Conclusions:

The embryo/fetus dose from F-18 FDG PET/CT was <15 mGy, however, questioning the women's childbearing prior to scintigraphy is the first-line strategy to avoid accidental radiation exposure and stochastic risks.
Non-semisimple 3-manifold invariants derived from the Kauffman bracket
Authors: De Renzi Marco , Murakami Jun
Published: March 2022

We recover the family of non-semisimple quantum invariants of closed oriented 3-manifolds associated with the small quantum group of

\mathfrak{sl_2}

using purely combinatorial methods based on Temperley–Lieb algebras and Kauffman bracket polynomials. These invariants can be understood as a first-order extension of Witten–Reshetikhin–Turaev invariants, which can be reformulated following our approach in the case of rational homology spheres.
An uncoupled limit model for a high-contrast problem in a thin multi-structure
Authors: De Maio Umberto , Gaudiello Antonio , Sili Ali
Published: March 2022

We investigate a degenerating elliptic problem in a multi-structure

\Omega_\varepsilon

of

\mathbb{R}^3

, in the framework of the thermal stationary conduction with highly contrasting diffusivity. Precisely,

\Omega_\varepsilon

consists of a fixed basis

\Omega^-

surmounted by a thin cylinder

\Omega_\varepsilon^+

with height

1

and cross-section with a small diameter of order

\varepsilon

. Moreover,

\Omega^+_\varepsilon

contains a cylindrical core, always with height

1

and cross-section with diameter of order

\varepsilon

, with conductivity of order

1

, surrounded by a ring with conductivity of order

\varepsilon^2

. Also

\Omega^-

has conductivity of order

\varepsilon^2

. By assuming that the temperature is zero on the top and on the bottom of the boundary of

\Omega_\varepsilon

, while the flux is zero on the remaining part of the boundary, under a suitable choice of the source term we prove that the limit problem, as

\varepsilon

vanishes, boils down to two uncoupled problems: one in

\Omega^-

and one in

\Omega^+_1

, and the problem in

\Omega^+_1

is nonlocal. Moreover, a corrector result is obtained.
Designing the Design Space: Evaluating Best Practices in Tradespace Exploration, Analysis and Decision-Making
Authors: Daniels Julia , Turner Cameron J. , Wagner John , Masoudi Nafiseh , Agyemang Malena , Hartman Gregory , Rizzo Denise , Gorsich David , Skowronska Annette , Agusti Rachel
Published: March 2022

Determining the validity of the design space early in the conceptualization of a project can make the difference between project success and failure. Early assessment of technical feasibility, project risk, technical readiness and realistic performance expectations based on models with different levels of fidelity, uncertainty, and technical robustness is a challenging mission critical task for large procurement projects. Tradespace exploration uses model-based engineering analysis, design exploration methods, and multi-objective optimization techniques to enable project stakeholders to make informed decisions and tradeoffs concerning the scope, schedule, budget, performance and risk profile of a project. As the intersection with a number of project stakeholders, tradespace studies can provide a significant impact upon the direction and decision-making in a project. Yet, the act of studying the tradespace is data intensive, subject to variability, uncertainty complexity and ambiguity (VUCA). These properties of the data in the tradespace present challenges in both conducting tradespace studies but also in presenting the results of tradespace studies to a variety of stakeholders. In this work, data collected from the literature concerning tradespace exploration, analysis and decision-making practices is reviewed and analyzed to identify the best practices and common pitfalls experienced by organizations conducting tradespace studies. Using a series of interviews conducted with members of a tradespace study group, the authors then proceed to use these best-practices and common issues to evaluate the tradespace study group to reveal avenues for improvement and areas of excellence within that group. Through this paper, other organizations can perform similar self-assessments to improve their capabilities with respect to tradespace studies.
A Naturalistic Study of Vehicle Acceleration and Deceleration at an Intersection
Authors: Danaher David , McDonough Sean , Donaldson Drew , Cochran Reece
Published: March 2022

Approaching an intersection and braking to a stop, as well as accelerating from a stop, is a common occurrence in daily life. While the experience is routine, the actual rate of deceleration and acceleration has not been analyzed from an orthogonal aerial perspective. The aerial perspective provides video footage that allows for accurate planar motion tracking and does not influence the drivers’ actions in any way. This paper examines the behavior of drivers at two separate signal light controlled intersections to determine both the rate at which they slow down to a stop, and also the rate at which they accelerate through the intersection after a signal change. The paper will also address the acceleration rate differences of vehicles who are first to reach the intersection in comparison to those that are directly behind another vehicle, as well as the lag in reaction between vehicles as they begin to accelerate from a stop.
Crash Safety Design for Lithium-ion Vehicle Battery Module with Machine Learning
Authors: Zhu Feng , Logakannan Krishna
Published: March 2022

Lithium-ion battery systems have been used as the main power source for electric vehicles due to their lightweight and high energy density. The impact safety of these battery systems has been a primary issue. In this work, the crashworthiness design of a typical vehicle battery module is implemented through numerical (finite element) simulations integrated with machine learning algorithms (decision trees). The module with multiple layered porous cells is modeled with a simplified, homogeneous material law, and subjects to the impact of a cylindrical indenter. The main protective component on the module - cover plate is designed as an energy absorbing sandwich structure with a core of cellular solids. Large scale simulations are conducted with various design variable values for the sandwich structure, and the results form a design (simulation) dataset. Based on the dataset, machine learning is applied to the sandwich cover plate design to: (1) correlate the design variables to the response; (2) investigate the complex inter-relationship between design variables; and (3) derive decision-making rules to achieve the designs with highest energy absorbing capability.
Ranks of Identity Difference Transformation Semigroup
Authors: Jude. A. Omelebele , O. G. Udoaka , I. U. Udoakpan
Published: March 2022

This study focuses on the ranks of identity difference transformation semigroup. The ideals of all the (sub) semigroups; identity difference full transformation semigroup (IDT_n), identity difference order preserving transformation semigroup, (IDO_n), identity difference symmetric inverse transformation semigroup( IDI_n), identity difference partial order preserving symmetric inverse transformation semigroup( IDPOI_n) and identity difference partial order preserving transformation semigroup ( IDPO_n) were investigated for rank and their combinatorial results obtained respectively.
Study of Potato Growers in Haryana with Special Reference to the Production Constraints
Authors: Deep Vishwas
Published: March 2022

The present study determines that the potato growers are facing many constraints in the production process of potato in Haryana state. The supply chain of different agricultural commodities in India is facing challenges starting from the inherent problems of the agricultural sector. The farmers in the study area are facing various major constraints in the cultivation of potato. The study was carried out at Pipli and Shahabad blocks of Kurukshetra district and, Radaur and Sadhaura blocks of Yamuna Nagar district of Haryana state as both districts is the highest producer of potato in the state. Fifty number of farmers were surveyed from each block of the district thus covering a total of 200 farmers. Henry and Garrett’s technique was utilized to determine the constraints faced by the potato growers in the area. The cost of potato seed is very much high and is given the first rank among all the constraints. There is a need to formulate favorable policies by the central as well as state government regarding the direct procurement of the farmers by the government agencies to maximize the producer’s share in consumer’s rupee. The farmers always faces disease incidence and there is a need to develop disease resistant varieties by the research institutions to minimize the losses of the farmers. The raw input materials should be made available at nearest point to the farmers to minimize the cost of cultivation of the potato
Transición IPV4 a IPV6
Authors: Jaimes Miguel Ángel Ruiz , Sosa Sandra Elizabeth León , Báez Irma Yazmín Hernández
Published: March 2022

En la actualidad se manejan redes de IPv4, sin embargo, es muy importante aclarar que las direcciones IPv4 se están agotando por lo que las empresas e instituciones que manejan IPV4 deberán actualizarse lo más pronto posible para evitar la limitación de crecimiento de la red. Es importante mencionar que surgió un nuevo protocolo IPv6 que ofrece la mejor amplitud en cantidad de direcciones ya que su longitud es de 128 bits lo que ayuda a mitigar el problema de IPv4, ofrece un sistema de direccionamiento escalable y amplio. Dentro de las grandes ventajas que tiene el protocolo IPv6 es internet sin límites y sumado a esto grandes mejoras como es la seguridad y eficiencia, de manera que al tener una dirección IP más larga y compleja será más difícil un ataque a la red, ofrece la autoconfiguración de direcciones. Se pretende saber qué tan factible y viables es realizar la conversión de la red de la institución de IPV4 a IPv6, confirmar los beneficios que ofrece la configuración IPv6 y que la red sea dé mayor escalabilidad de acuerdo a las necesidades de la Institución
Covid Anxiety and Immune System
Authors: Anjali A  , Satheesh K
Published: March 2022

In the era of global transmission, when all the luxurious concept stands meaningless people are forced to believe the concept of ‘individualistic approach in disease management’. This pandemic COVID 19 has been an eye opener which showed the world that there doesn’t exists any magic pill. The one and only protector we have is our immune system. Many people are prone to ill health due to their irregular dietary habit (Āharaja), activities (Vihāraja) change in climate, on the other hand, some people remain healthy in spite of violating healthy rules and do not get affected by any disease. This is because of the variation in their immune power. Ayurveda described Vyādhikşhamatva in more detail and magnificent way which can be considered equivalent to modern concepts of immunity. The term Vyādhikşhamatva is made up of two words; Vyādhi (disease) and kşhamatva (suppress or overcome). Ayurveda describes numerous health practices as Dinacarya, Ritucarya, Rasāyana, Sadvritta, Acāra rasāyana, Yoga and meditation to help mind and body to thrive. Homeostasis of Ojas, Agni, Srotas, Doşa and Duşya along with and associated is the pleasant state of sensory organs and mind, soul essential for good health. The government interventions during COVID-19 like Punarjani, Sukhayushyam, Swasthyam, Niramaya, Ayur raksha clinics which aims at strengthening the preventive mechanism gives Ayurveda a new ray of hope to globalize its importance.
Facilitative Leadership Collaborating on Prevention of Corruption in Goods and Services Auctions in South Sulawesi Province
Authors: Padli Padli , Ibrahim Muh Akmal , Nara Nurdin , Sukri Sukri
Published: March 2022

Collaborating to avoid corruption in the auction process for products and services will be a success or failure depending on the leadership of each entity. This is due to the fact that it includes a wide range of parties, including the UKBJ, APIP, police, prosecutors, providers (enterprises), and civic organizations. In order to thwart corruption, this research examines how leaders might make cooperation easier. In South Sulawesi Province, there are auctions of commodities and services related to the health industry. A method known as descriptive qualitative research has been used in this study to better understand the data. Interviews, literature review, observation, and documenting are all forms of data collecting. Corruption prevention efforts in South Sulawesi Province's Health sector had not been properly facilitated by the leadership of the auction of goods and services. There has been room for all parties to participate in the health sector auction of goods and services, as indicated by top management of the auction of goods and services and briefing each technical implementer in their respective institutions to master the applicable rules and take a moral approach to strengthening credibility through the involvement of law enforcement and elements of society member. However, if the leadership intervenes, each technical implementer is more likely to commit fraud. While the MoU has yet to be signed, the parties participating in the partnership are still able to work together in an informal capacity.
LA CONFIGURACIÓN LEGAL Y JURISPRUDENCIAL DEL DERECHO CONSTITUCIONAL A LA PROTECCIÓN DE LA SALUD
Authors: CANTERO MARTÍNEZ JOSEFA
Published: March 2022

En este trabajo se pretende analizar la significativa evolución legal y jurisprudencial que en los últimos años se ha producido del derecho a la protección de la Salud consagrado en el artículo 43 de la Constitución. Se examina especialmente la interpretación que han venido realizando nuestros jueces y tribunales respecto de este derecho cuando ha entrado en colisión con algunos derechos fundamentales, como el derecho a la libertad religiosa, el derecho a la integridad física o el derecho a la igualdad, toda vez que estos pronunciamientos nos permiten ir delimitando el contorno, la extensión y los límites del derecho a la protección de la salud. Acontece, no obstante, que en ocasiones la interpretación realizada demuestra la existencia en nuestro ordenamiento sanitario de algunos resquicios de una concepción paternalista de la medicina, lo que no deja de ser un significativo elemento discordante en la importantísima evolución hacia la plena autonomía del paciente experimentada en los últimos años en este ámbito.

Konstituzioak 43. artikuluan aitortzen duen osasunaren babeserako eskubideak bilakaera garrantzitsua izan du azken urteetan, hala legeetan nola jurisprudentzian, eta horixe aztertzea du xede lan honek. Osasunaren babeserako eskubidea funtsezko beste eskubide batzuekin sartzen da talkan, hala nola erlijio-askatasunerako eskubidearekin, osotasun fisikorako eskubidearekin edo berdintasun-eskubidearekin, eta gure epaile eta epaitegiek horri buruz egindako interpretazioa aztertzen da bereziki. Izan ere, interpretazio hori jakinarazteko haiek egindako adierazpenetan aurkituko ditugu osasunaren babeserako eskubidearen mugak, hedadura eta soslaia zedarritzeko aukera. Hala ere, interpretazio horrek, batzuetan, erakusten du gure osasun-antolamenduan badirela medikuntzaren ikuspegi paternalista baten kutsua darien zirrikituak, eta hori ez dator bat azken urteetan eriaren autonomia osorako bidean gertatu den bilakaerarekin.

In this work we try to analyse the noteworthy legal and caselaw evolution that right to health protection established by article 43 of the Constitution has suffered during last years. It is specially studied the interpretation given by our judges and courts in relationship with this right when it collides with the right to religious freedom, with the right to physical integrity or with the right to be equally treated because all those rulings and judgments let
us mark the contours, the extension and limits of the right to health protection. It happens, however, that sometimes the given interpretation shows that in our health legal order there are some chances to a paternalist conception of medicine which is after all a clear discordant element in this very important evolution towards the full autonomy of patients as experienced in this field during last years.
LA CONTRATACIÓN DE LAS ADMINISTRACIONES PÚBLICAS Y DE LOS DEMÁS ENTES DEL SECTOR PÚBLICO. NOVEDADES. PROCEDIMIENTOS DE ADJUDICACIÓN
Authors: RAZQUIN LIZARRAGA MARTÍN MARÍA
Published: March 2022

Este estudio trata sobre los contratos que celebran las Administraciones Públicas y demás entes del sector público, dando cuenta de las novedades introducidas al respecto por la nueva Ley de Contratos del Sector Público 30/2007, de 30 de octubre. La exposición se centra, primero, en analizar las novedades más relevantes que han significado la variación del ámbito subjetivo y de la tipología de los contratos. Después se hace especial incidencia en los procedimientos de adjudicación de los contratos públicos, resaltando las implicaciones derivadas de la aplicación de la Directiva 2004/18/CE. Para ello se explican los trámites generales del procedimiento de adjudicación así como los diferentes procedimientos a que pueden acudir los entes del sector público para la adjudicación de los contratos.

Azterlan hau herri-administrazioek eta arlo publikoko gainerako entitateek egiten dituzten kontratuei buruzkoa da, eta Arlo Publikoko Kontratuen urriaren 30eko 30/2007 Lege berriak sartu dituen berrikuntzen berri ematen du. Azalpenak, lehenik, kontratuen eremu subjektiboan eta tipologian gertatu diren berrikuntza nagusiak aztertzen ditu. Gero, kontratu publikoak esleitzeko prozedurak aztertzen dira xeheago, eta 2004/18/CE Zuzentarauaren aplikazioaren ondorioak nabarmentzen. Horretarako, esleipen-prozeduraren izapide orokorrak azaltzen dira, eta arlo publikoko erakundeek kontratuak esleitzeko zein prozeduratara jo dezaketen ere bai.

This paper studies the public procuremet of the Public Administrations and also of the rest of bodies which are inside of the public sector. It analyses the new Spanish Act (2007) about public procurement. The paper explains the new more important rules of this Act of 2007. This Act changes the public bodies or agencies subject to the Act and the new types of public contracts. Mainly, this paper studies the new procedures for the award of the public
procurement contracts. Also there are many mentions to the EU Law, especially, to the Directive 2004/18/EC. It explains the general steps of the award and also the different procedures of the public bodies for the award of their contracts.
The role of third-generation dual-source dual-energy computed tomography in characterizing the composition of renal stones with infrared spectroscopy as the reference standard
Authors: Shalini Shweta , Kasi Arunachalam Venkatesh , Kumar Varatharajaperumal Rajesh , Mehta Pankaj , S. Thambidurai , Cherian Mathew
Published: March 2022

Purpose

The aim of our study was to prospectively evaluate the role of third-generation, dual-source, dual-energy computed tomography (DECT) in the characterization of renal calculi, with ex vivo renal stone evaluation using Fourier transform infrared spectroscopy (IS) as the reference standard.

Material and methods

In our study 50 patients with history suggestive of renal calculi were subjected to DECT using 100 kVp and Sn150 kVp. With DECT, renal stone attenuation at low and high kVp was attained, and the attenuation ratios were measured. The result of DECT was compared with IS to identify the chemical composition of the extracted renal stones. IBM SPSS version 22 was used for statistical analysis.

Results

In our study, the mean attenuation ratio of the renal stone was 1.57 ± 0.25. Out of 50 patients, the stones of 39 patients were predicted as calcium-containing stones, in 4 patients as cystine stones, and in 7 as uric acid stones on DECT. In IS analysis, 43 patients had calcium-containing stones, and 7 patients had uric acid stones. The accuracy rate of DECT for detecting calcium and uric acid stones in our study were 90% and 100%, respectively. The positive predictive value for the DECT to assess the chemical composition of renal calculi was found to be 92%.

Conclusions

Third-generation DECT scan had 100% accuracy in differentiating uric acid stones from non-uric acid stones in our study. Because the treatment is different for different chemical compositions of stones, identification of specific chemical components is very important, and it can be accurately done by DECT.
ANALISIS PENEGAKAN HUKUM TINDAK PIDANA YANG DILAKUKAN DALAM LINGKUP PINJAMAN ONLINE ILEGAL DI INDONESIA
Authors: Manayra Aisha Putri Indradjaja  , Sigid Suseno  , Rully Herdita Ramadhani
Published: March 2022

The development of the digital era, especially in the technological aspect, has led to various innovations in the field of financial services, one of them is Financial Technology. The type of Financial Technology that is in huge demand and often used is Financial Technology Lending or information technology-based on lending and borrowing services or also known as online loans. Nowadays, Financial Technology Lending used as an alternative investment and practical source of funding for the community. However, along with developments, the convenience provided by Financial Technology Lending services can pose a risk of a criminal act, especially in the cyber aspect. Although in the practice law enforcement related to criminal acts committed within the scope of illegal online loan has been carried out. In reality illegal online loans are still rife in the community. This study aims to examine law enforcement and obstacles related to law enforcement against criminal acts committed within the scope of illegal online loans in Indonesia. By using a normative juridical approach, secondary data sources will be analyzed qualitatively, the following research results are obtained: (1) A description of the factors that affects law enforcement has been applied in tackling criminal acts committed within the scope of illegal online loans; (2) Even though law enforcement has been carried out, in practice there are still obstacles that not being able to eradicate criminal acts that occur within the scope of illegal online loans.
Enfoques ante una reforma de la Ley de Transparencia
Authors: Sierra-Rodríguez Javier
Published: March 2022

Ante la constitución de un grupo de trabajo sobre la reforma de la Ley de Transparencia, se reflexiona sobre posibles perspectivas de mejora. El autor propone que la modificación no se limite a retocar o perfeccionar los contenidos que ya aborda la ley, sino que, además, se valore la ampliación de su enfoque y se incluyan principios de publicidad relativos a la transparencia informativa de la esfera gubernamental.
Análisis de los Informes Nacionales Voluntarios en África: Marruecos, Senegal, Etiopía y Namibia
Authors: Díaz Lafuente José
Published: March 2022

El presente artículo persigue el análisis de la implementación de los ODS en el continente africano mediante el estudio comparativo de los Informes Nacionales Voluntarios (INV) presentados por Marruecos, Senegal, Etiopía y Namibia. A tal efecto, se presenta un análisis crítico del grado de institucionalización de la Agenda 2030, de los avances y desafíos en el cumplimiento de los ODS, de los sistemas de recopilación de la información, de evaluación y de seguimiento de la implementación de los ODS y de los mecanismos y procesos de comunicación y de participación ciudadana.
Legal Action for Climate Protection — impulses on the international level from the German Federal Constitutional Court: the Court Order from March 2021 on the Unconstitutionality of the Federal German Climate Protection Act
Authors: Tomerius Stephan
Published: March 2022

Against the background of the international climate protection aim deriving from the “Paris Agreement” of December 2015, demanding a limitation of global warming to 1,5  Celsius at best, the public discussion and anger on the mid- and longterm consequences of a constantly growing greenhouse effect have clearly risen. Along with that, “climate litigation” has turned into serious means to sue governments for inadequate measures to reach international and domestic climate protection goals. In a line of several legal actions and high court decisions in different countries during the last years is the court order of the Federal German Constitutional Court from March 2021. The judges considered the German Federal Climate Protection Act unconstitutional due to a lack of clearing a reliable legal path to reach the CO2-reduction goals and this decision was seen as a milestone in climate litigation. Combined with the obligation of the state to protect the natural resources by legislation, the court invented the “advance interference-like effect”on future generations and the “intertemporal guarantees of freedom”, two legal figures which could be possibly applied to constitutional law abroad and thus fertilize argumentation in climate litigation outside of Germany, too.
Marcos institucionais para as dimensões humanas: reflexões para áreas marinhas protegidas brasileiras
Authors: Barreto Giovanna Carla , Silva Manuela Dreyer da , Nascimento Décio Estevão do , Serafini Thiago Zagonel , Medeiros Rodrigo Pereira
Published: March 2022

Com o aumento da complexidade nas discussões à cerca da conservação da natureza, o conceito de Dimensões Humanas (DHs) também foi sendo trabalhado na literatura científica e percebido na aplicação de abordagens alternativas de gestão dos recursos naturais. Importantes marcos institucionais nacionais e internacionais (políticas, diretrizes e metas) pautaram essas discussões, e aqui interessa especialmente aqueles associados à conservação de Áreas Marinhas Protegidas (AMPs) e pesca artesanal. Neste contexto, o presente artigo teve como objetivo sistematizar os principais marcos institucionais adotados para o delineamento deste conceito de DHs, vinculando-os a componentes trazidos pela literatura científica nessa temática. Para tanto, foram utilizados os seguintes procedimentos metodológicos: (1) elaboração de um quadro síntese com a descrição desses principais marcos, acompanhado de uma análise de estratégias políticas associadas; e (2) estabelecimento de conexões com componentes de DHs encontrados na literatura. A pesquisa apontou a teoria dos comuns como grande influenciadora da criação do conceito e que o seu entendimento vai muito além da ideia unívoca de dimensões humanas como controle e gestão do comportamento humano. Já os componentes e as suas conexões evidenciaram desafios importantes para a incorporação das DHs nas práticas atuais de gestão pesqueira, mostrando que a gestão dos recursos naturais em AMPs apresenta indicativos de um modelo em transição; porém, ainda prevalecem elementos de uma gestão tecnocrática e centralizadora.
Genetic polymorphisms in interleukin-1beta were associated with typhoid fever in Babylon City in Iraq
Authors: Mussa Zaineb Fareed Hassan , Sultany Shaimaa Jassim Al
Published: March 2022

A total of 50 clinical samples were taken from the blood of typhoid fever patients who visited Al-Hillah Surgical Teaching Hospital and private laboratories in the AL-Hillah/Babylon region between February and August 2021. This research included 50 people who looked to be healthy and disease-free. Individuals with genotype GA were significantly represented among the patients with typhoid fever: 33 (66%), P-value = 0.0030, as compared with healthy control subjects, 18 (36%), and had an increased risk of developing typhoid fever infection. The IL-1beta (G) allele was less frequent among patients (51%, n =51) than control, and the (A) allele was more frequent among patients than control (49%, n =49). The results showed that there was a significant association between GA genotype and typhoid fever under most inheritance models. The A allele represents a risk factor for patients with typhoid fever and the inheritance of codominant, dominant, and overdominant models as risk factors. The GA genotype has an odd ratio of 4.07 (1.54–10.79) in the model of inheritance. Codominant and dominant models have a related odd ratio of 3.04 (1.21–7.60) and the overdominant model has a related odd ratio of 3.45 (1.52–7.85).
Impacto de la economía del conocimiento en la Universidad Pública
Authors: Aboslaiman Lucrecia
Published: March 2022

Mediante este trabajo se propone reflexionar acerca   de la incidencia de la economía del conocimiento en la   Universidad Pública y cómo impacta en la función de   extensión, esta última entendida como construcción   de diferentes sistemas de acciones dirigidas a   promover y potenciar el vínculo universidad‐sociedad, desde la integración de las funciones universitarias, las   disciplinas y saberes. Esto implica un cuestionamiento   a lo instituido, permitiendo cambios culturales   profundos, la reconstrucción del conocimiento   académico, el abordaje interdisciplinario, compromiso   ético, social, político y la innovación.  

La metodología utilizada es descriptiva con base en   textos pertinentes, desde la búsqueda de bibliografía   y fuentes adecuadas. Se tiene como conclusión que la   política extensionista que forma parte de la política   educacional, debe tener como objetivo el fundamento   que la sociedad demanda en la construcción de   saberes y en la extensión de los mismos a una sociedad   compleja y globalizada.
ESP for Interpreters and Translators: Foreign Language Provision or Integrated Education?
Authors: Kyrda-Omelian Alla , Viktorova Lesia , Kutsenko Mykola , Bobyr Yuliia , Mamchur Kostiantyn , Shcherbyna Olena , Lahodynskyi Oleksandr , Bloshchynskyi Ihor
Published: March 2022

The paper is a complex study of advanced training of state employees, including servicemen on the positions of interpreters and translators. The research is aimed at efficient organization of English for Specific Purposes course taking into account specific needs of the main stakeholders. The purpose of the training is the efficient use of English by course participants, who are Philology specialty graduates, in professional settings. The learners are expected to gain knowledge and experience in the positions of interpreters or translators of the Division of International Cooperation, the Division of Military and Technical Cooperation, the Division of Informational and Analytical Support of state bodies of Ukraine. On the basis of the insights gained from designing an ESP course for state employees on such positions, analyzing their job responsibilities and all the stakeholders’ needs, reviewing literature on ESP and integrated education, this paper is intended to provide theoretical background and practical assistance for ESP specialists involved in research and design processes of the courses as well as for those who prepare learning materials for interpreters and translators seeking problem-based training to develop their professional competence.
De Manchester a São Paulo por Engels: condição espacial de moradia e tríplice precariedade de reprodução da classe trabalhadora periférica
Authors: Oliveira Sandro Barbosa de
Published: March 2022

Este artigo homenageia os duzentos anos do nascimento de Friedrich Engels inspirado em seu estudo “A situação da classe trabalhadora na Inglaterra”, por meio de uma análise das condições de moradia de parte dos trabalhadores na metrópole de São Paulo, a partir das percepções do autor sobre Manchester, ao mostrar semelhanças e diferenças em seus processos de urbanização, desenvolvimento desigual no capitalismo e como as situações de precariedade das moradias impactam as condições de vida do proletariado. A partir das teses dessa obra que destacam a centralização na produção de mercadorias, a “solução” da “questão social” e o proletariado enquanto sujeito nas lutas, analisamos o histórico de construção de vilas operárias, favelização da cidade e autoconstrução de moradias por trabalhadores em São Paulo por meio da condição espacial, com objetivo de ampliar a apreensão dessas desigualdades urbanas pela tríplice precariedade entre trabalho, moradia, deslocamento e mediante ao estudo de caso de uma doméstica.
“Greve Geral! Greve Geral!”: austeridade e protestos contra as reformas fiscais (2016-2019)
Authors: Santos Jonatha Vasconcelos
Published: March 2022

A última década tem sido marcada por uma intensa diversificação das formas de ação coletiva e do perfil dos atores engajados em mobilizações de rua. Diante disso, este artigo analisa os protestos, ocorridos em Sergipe, contra as reformas fiscais implementadas pelos governos Michel Temer (2016-2018) e Jair Bolsonaro (2019 – atual). Especificamente, o objetivo desse artigo consiste em investigar os enquadramentos, as redes de mobilização e a dinâmica dos protestos em torno da luta contra as reformas fiscais em Sergipe. Para isso,o recorte empírico consiste em 92 protestos catalogados no banco de dados Mobilizações de Rua em Sergipe (2010-2020) e a metodologia utilizada foi a análise de eventos de protestos. Os resultados apontam para a construção de três redes de mobilizações em torno das quais partidos políticos, sindicados movimentos sociais e coletivos construíram uma dinâmica contestatória que se caracteriza pela heterogeneidade dos repertórios de ação e pelo uso da greve enquanto ação tática.