bluuebunny/crossref_metadata_2025 huggingface dataset:
Optical biosensor for biogenic amines detection used a porous silicon matrix
Authors: Contreras Rozo J. A. , Severiano Carrillo F. , Gayou V. L. , Martínez Gutierrez H. , Delgado Macuil R.
Published: May 2021

The content of biogenic amines has been studied due to the toxicity of these compounds in humans when are consumed exogenously, and is used as an indicator of quality in the food industry. The manly method for its determination is high performance liquid chromatography. However, it requires a long time for analysis. An alternative method is the use of biosensors, porous silicon with gold nanoparticles were obtained by electrochemical attack assisted with metal salt. These substrates were used for the construction of a biosensor capable of detecting BA using diamine oxidase enzyme as an element of biological recognition and is binding using the self-assembled monolayers method. The correlation between scanning electron microscopy, X-ray dispersive energy spectroscopy, and Fourier Transform infrared spectroscopy analysis, demonstrated the correct construction of the biosensor and the detection of biogenic amines by interaction with the enzyme. Finally, with the built biosensor it was possible to detect three important biogenic amines found in food.
Logros en ciencias de la complejidad en el IFUNAM: una recopilación incompleta
Authors: Boyer D.
Published: May 2021

A pesar de que la complejidad se suele considerar como un paradigma joven, que irrumpió hace poco en áreas muy diversas de la ciencia, la investigación en sistemas complejos tiene una larga tradición en México. Se inició en el Instituto de Física en los años 70 y Germinal Cocho fue un actor central de su desarrollo ahí y en la UNAM, a lo largo de cuatro décadas. Aquí presentamos una breve revisión, necesariamente incompleta, de logros obtenidos en varias áreas de la complejidad en el Instituto de Física por Germinal Cocho y sus numerosos colaboradores y colegas.
Complex dynamics of passively mode-locked fiber lasers with strict polarization control
Authors: Pottiez O. , Bracamontes-Rodriguez Y. E. , Lauterio-Cruz J. P. , Ibarra-Villalon H. E. , Hernandez-Garcia J. C. , Santiago-Hernandez H. , García-Sánchez E. , Torres-Muñoz O.S. , Bello-Jimenez M.
Published: May 2021

In this work we browse an overview of the complex dynamics that arise in the non-stationary modes of operation of partly mode-locked fiber lasers under strict polarization control. Both ring and figure-eight cavities implementing saturable absorber mechanisms that rely on nonlinear polarization rotation were considered. The use of twisted fiber ensures robust operation, whereas precise polarization adjustments allow tailoring the nonlinear switching characteristic in a clear and repeatable manner. The enhanced flexibility of these sources allowed identifying and studying a broad spectrum of peculiar dynamics, in particular by implementing the temporal and spectral mapping techniques. These include the emergence, fusion, splitting, complex evolution and eventual decay of chaotic bunches of radiation, which are also subject to large spectral shifts, ample quasi-periodic instabilities, extreme-intensity events or the creation of solitons, among others, as well as the complex evolution of massively multiple soliton states. Finally, with the help of numerical simulation, several aspects of the physics underlying these puzzling behaviors could be elucidated.
Temperature Sensor Using Fiber Ring Laser Based On a Core-Offset Mach-Zehnder Interferometer
Authors: Contreras Marco Antonio
Published: May 2021

The development of fiber optic sensors receives special interest since they can be used in multiple applications. As a result, fiber optic laser-sensor schemes had emerged as a reliable device, due to its characteristics such as: high power, low threshold, and high stability. In this work, it is proposed a fiber laser-sensor based on a ring cavity configuration.  The cavity is operated by a core-offset Mach-Zehnder interferometer, which is used as a wave selection filter and temperature detection device. Here, the proposed fiber laser-sensor exhibits sensing properties such as sensitivity of 0.03119 pm/°C , dynamic range of 90ºC and a signal to noise ratio of 52 dB
Impact of higher-order optical fiber modes for photon-triplet generation
Authors: Garay-Palmett K. , Domínguez-Serna F.
Published: May 2021

This paper presents a study of the phasematching properties of the third-order parametric down-conversion process in multimode optical fibers with a step-index profile. Through this process, entangled photon triplets can be generated in the spontaneous regime. We show that phasematching is achieved in a wide range of fiber geometries, provided that the pump field propagates in a higher-order mode. Furthermore, we show the nonlinear coefficient and the absolute emitted flux for each source configuration, evaluated from expressions derived by us in previous theoretical studies concerning the spontaneous and stimulated emission regimes.
Analysis of whispering gallery modes resonators: wave propagation and energy balance models
Authors: Rivera-Pérez E. , Díez A. , Cruz J. L. , Silvestre E. , Andrés M. V.
Published: May 2021

Electromagnetic whispering gallery modes (WGM) are surface waves guided by the curvature of an interface. Microspheres, microdisks and microcylinders –as for example standard optical fibers– are high quality microresonators for the WGM. In fact, they can be regarded as compact and small ring resonators. Here, we present a comparison between wave propagation and energy balance models, stablishing the equivalence and discussing the basic characteristics of these two complementary approaches.
Fiber optic system to measure adulteration in liquids using an RGB detection
Authors: Vera-Duarte O. X. , Filoteo-Razo J. D , Estudillo-Ayala J. M. , Hernandez-Garcia J. C. , Jauregui-Vazquez D. , Sierra-Hernandez J. M. , Martinez-Angulo J. R. , Martin-Vela J. A. , Rojas-Laguna R.
Published: May 2021

In this paper, we propose a fiber optic system to measure the changes in the RGB composition of light in liquid solutions using a plastic optical fiber (POF) as an intrinsic sensor. The measurement system is composed of a 3 W white light-emitting diode as the light source, a 20 cm long U-shaped POF, and an RGB photodiode array that allows us to detect the changes in the RGB composition of the light propagating through the POF. The U-shaped POF has a length of 5 mm without coating, which remains in contact with the liquid solutions. The tests were performed with different concentrations of a mixture of tequila and water. The results obtained with the RGB photodiode array showed that the system has a resolution of 0.39 % and a color change sensitivity of 0.1, 0.6, and 0.4 8–bits/% of sample for red, green, and blue colors, respectively. These results will allow us to design a low-cost prototype to measure the amount of adulteration in liquids.
Visualization Technologies for Learning and Teaching Veterinary Acarology and Entomology
Authors: Vega-Garzón Juan C. , Robayo-Sánchez Laura N. , Cruz-Maldonado Oscar A. , Cortés-Vecino Jesús A.
Published: May 2021

Educational technologies are tools and resources used for improving teaching, learning, and creative inquiry. Visualization technologies (VTs) fall within this category and comprise a high diversity of strategies from simple infographics to complex forms of visual data analysis. Traditionally, parasitology has been a challenging subject in medical and veterinary degree courses due to the high number of scientific names, morphological characters, and complex life cycles, among other factors. This has been reinforced by conventional teaching methods with limited innovation strategies. Here we present the design and evaluation of an interactive album of veterinary acarology and entomology, “Álbum Interactivo de Acarología y Entomología Veterinaria” (AIAEV). This tool was assessed through three strategies: (1) a mean grade comparison between veterinary parasitology classes before and after VT implementation, (2) a system usability scale (SUS), and (3) a student/user satisfaction index. The grade value was higher in the class after implementation, the SUS total score was 80.05 (excellent), and 93.75% considered it a useful tool. This is the first study aimed at investigating the use of VTs to teach veterinary acarology and entomology and shows promising results to develop and implement digital technologies in this and other veterinary curricula disciplines.
Environmental Sustainability in Veterinary Medicine: An Opportunity for Teaching Hospitals
Authors: Schiavone Stephanie C.M. , Smith Sage M. , Mazariegos Isabella , Salomon Michelle , Webb Tracy L. , Carpenter Molly J. , Baumgarn Stacey , Duncan Colleen G.
Published: May 2021

Climate change is one of the greatest public health threats of the twenty-first century. Recent surveys of veterinary students and practicing veterinarians have highlighted their concerns about the impacts of climate change on animal health and a strong desire to be knowledgeable about the practice and promotion of environmental sustainability within clinical practice. Most American Veterinary Medical Association (AVMA)–accredited veterinary schools have a veterinary teaching hospital (VTH) where veterinary students receive their core clinical education. Given this, VTHs may provide opportunities for students to learn how veterinary clinics can decrease their environmental footprint and actions they could incorporate into their future clinical work. To assess the feasibility of and support for introducing environmentally sustainable practices into VTHs, we distributed an anonymous online survey to all AVMA-accredited veterinary schools with an associated VTH. Responses were received from 843 individuals representing 23 VTHs in 7 countries. While the overwhelming majority of responding personnel believe this is an important topic, there is little evidence that sustainable behaviors are being practiced or showcased within VTHs. Respondents were most interested in working to increase recycling and reduce general waste and energy consumption within their hospitals. In addition to a lack of educational resources, funding was a commonly identified barrier to incorporating more environmentally sustainable practices. These results add to the growing evidence that enhanced incorporation of sustainability into veterinary medical education at all stages is needed and that VTHs provide a unique opportunity to lead by example.
Radicalizing Online
Authors: McCurdy Emmett
Published: May 2021

Radicalization is the transition into acceptance and approval of extremist beliefs and actions, including condoning or committing acts of violence. In recent decades, the internet has played a crucial role in the radicalization of extremists and terrorists, as well as facilitating radical groups' recruitment efforts. The present review briefly discusses what radicalization is and how it unfolds in a general sense, before exploring how the internet is involved in three kinds of radicalization. The first is the deliberate radicalization and recruitment of new members into formally organized extremist groups (e.g. white supremacist militias and radical Islamic terror groups), and the second is self-radicalization via the internet, wherein unstable, discontent, and/or disenfranchised individuals pursue increasingly radical ideas and communities online until they condone or commit acts of violence on their own, without formal membership into an organized group. The third type of radicalization explored is stochastic or probabilistic radicalization, in which individuals encounter seemingly or actually benign ideas, beliefs, and pundits online, and are slowly radicalized via increasingly bold and dramatic content being suggested by the recommendation algorithms of Google and Youtube. The review clarifies some distinctions between the three types, before a brief summary and discussion.

Content warnings: discussions of violence, bigotry, and hate.
التراث في شعر صخر حبش أبي نزار
Authors: ساري الديك نادي
Published: May 2021

التراث مفردة لها وقعها ودلالاتها في نفوس المنشئين للأدب، والمتلقين له على حدّ سواء، ما جعل الشعراء المعاصرين يتفاعلون معها عبر نصوصهم الإبداعية، وصخر حبش من الشعراء الذين فعّلوا التراث بكلّ مكوناته، ومقوماته في نصّهم الشعري، حيث عمد إلى خلق حالة شعرية ناجزة تعجُّ بصور التراث ومنجزاته، فكان التراث الإنساني حاضراً، وروحية التراث العربي والإسلامي شاخصة، ومتتابعة في نصوصه الشعرية، ما يجعل قصيدته تعجُّ بمقومات التراث ومكوناته. إن كان ذلك عبر الشخصيات التراثية، أو المسميات أو النصوص الإبداعية، متعددة المشارب والمنابت، دينية كانت أم أدبية، التي اتخذها متكأً لنصّه الشعري، وهذا لا يعني أنه أثقل نصّه بروحية التراث ومعطياته، وإنّما نجده يبني نصّاً موشّى بالتراث الذي أغنى النّصّ وجعله قريباً من النفوس المتلقية له، والمتفاعلة معه، لأنّ التراث أصبح لبنة فاعلة في جسد قصيدة صخر حبش الشعرية.
Diabetes Mellitus and the Development of Lumbar Canal Stenosis: Is There Any Relevance?
Authors: Kakadiya Ghanshyam , Saindane Kalpesh , Soni Yogesh , Gohil Kushal , Shakya Akash , Attar Mohhamad Umair
Published: May 2021

Study Design: Retrospective study.Purpose: To assess the relationship between the severity of lumbar canal stenosis (LCS) and type-II diabetes mellitus (DM).Overview of Literature: DM is a multiorgan disorder that has an effect on all types of connective tissues. LCS is a narrowing of the spinal canal with nerve root impingement that causes neurological claudication and radiculopathy. Identification of the risk factors of LCS is key in the prevention of its onset or progression.Methods: LCS patients were divided into three groups as per DM status: group A without DM (n=150); group B patients with well-controlled DM; and group C patients with uncontrolled DM. Groups B and C were subdivided into group B1: patients with DM with a duration of ≤10 years (n=76), group B2: DM with duration of >10 years (n=68), group-C1 DM duration ≤10 years (n=56), and group C2 DM duration >10 years (n=48). The severity of LCS was evaluated using the Swiss Spinal Stenosis Scale (SSSS) and Modified Oswestry Disability score (MODS). Operated patients ligamentum flavum sent for histological staining and quantitative immunofluorescence analysis.Results: The demographic data of groups did not show any difference except in age. There was no difference between the mean SSSS and MODS of groups A and B1. Groups B2, C1, and C2 had higher average SSSS and MODS than group A (p<0.05). Groups B2 and C2 had higher SSSS and MODS than groups B1 and C1. Group C1 and C2 had higher scores than groups B1 and B2 (p<0.05). The severity of LCS was significantly related to the duration of DM in groups B and C (p<0.05). Uncontrolled and longer duration of DM had significant elastin fibers loss and also higher rate of disk apoptosis, high matrix aggrecan fragmentation, and high disk glycosaminoglycan content.Conclusions: Longer duration and uncontrolled diabetes were risk factors for LCS and directly correlate with the severity of LCS.
Feasibility of Single-Stage Posterior Passive Correction and Fusion Surgery for Congenital Scoliosis in Adolescent Patients Who Have Attained Skeletal Maturity
Authors: Chiu Chee Kidd , Tan Rommel Lim , Gani Siti Mariam Abd , Chong Jessamine Sze Lynn , Chung Weng Hong , Chan Chris Yin Wei , Kwan Mun Keong
Published: May 2021

Study Design: Retrospective study.Purpose: To report the perioperative and radiological outcomes of single-stage posterior passive correction and fusion (SSPPCF) in adolescent patients who present with congenital scoliosis.Overview of Literature: The surgical treatment for congenital scoliosis is complex. There is no definitive guide on surgical options for skeletally matured adolescent patients who have congenital scoliosis.Methods: Patients with congenital scoliosis who underwent SSPPCF using a pedicle screw system were reviewed. We identified the following three surgical indications: (1) hemivertebra or wedge vertebra over the thoracic or thoracolumbar region with structural lumbar curves, (2) hemivertebra or wedge vertebra at the lumbar region with significant pelvic obliquity or sacral slanting, and (3) mixed or complex congenital scoliosis. The demographic, perioperative, and radiographic data of these patients were collected.Results: Thirty-four patients were reviewed. The mean patient age was 14.6±3.4 years. There were 13 hemivertebrae, three wedged vertebrae, two butterfly vertebrae, three hemivertebrae with butterfly vertebra, eight unsegmented bars, and five multiple complex lesions. The average surgical duration was 219.4±68.8 minutes. The average blood loss was 1,208.4±763.5 mL. Seven patients required allogeneic blood transfusion. The mean hospital stay duration was 6.1±2.5 days. The complication rate was 11.8% (4/34): one patient had severe blood loss, one had rod breakage, and two had distal adding-on. The Cobb angle reduced from 65.9°±17.4° to 36.3°±15.3° (p<0.001) with a correction rate (CR) of 44.8%±17.4%. The regional kyphotic angle decreased from 39.9°±20.5° to 27.5°±13.9° (p=0.001) with a CR of 19.3%±49.6%. Radiographic parameters (radiographic shoulder height, clavicle angle, T1 tilt, cervical axis, pelvic obliquity, coronal balance, and apical vertebral translation) showed significant improvement postoperatively.Conclusions: SSPPCF was a feasible option for adolescent patients with congenital scoliosis who were skeletally matured.
Are recorded lectures suitable for medical students?
Authors: Nabbout Ghassan , Bchennaty Dima , Zalloua Pierre
Published: May 2021

Background: During the Covid -19 lockdown, the Faculty of Medicine at the University of Balamand adopted the Webex platform to deliver the lectures live for the students. All lectures were also recorded and posted. This study compares the results of students who attended the live online lectures with those who only reviewed the recordings of the lectures, taking the previous year’s rank into consideration. Method: We retrieved attendance data of Med 2 students and their grades for 7 modules. We also had access to the previous year’s rank as predictor of outcome. The students had two types of exams, the standardized NBME questions and in-house questions prepared by the lecturers. The students rank from the previous year was used to divide the students into the top 20%of the class, the lower 20% and the rest. Analysis to assess the impact of attendance on outcome was made for the two types of exams, and for the different groups of students.Results: Our analysis shows a significant correlation between the two types of questions, and a significant correlation between attendance and the previous years’ rank. Also for all the groups, attendance had a significant contribution to the outcome, more significant among the top students and the bottom of the class students.Conclusion: This study shows the importance of attending lectures even if they are online, not only for the poor performing students but also for the top 20%. Recorded lectures may be a beneficial adjunct but not a replacement of live lectures, at least for now.
Improved surgeon performance following cadaveric simulation of internal carotid artery injury during endoscopic endonasal surgery: training outcomes of a nationwide prospective educational intervention
Authors: Donoho Daniel A. , Pangal Dhiraj J. , Kugener Guillaume , Rutkowski Martin , Micko Alexander , Shahrestani Shane , Brunswick Andrew , Minneti Michael , Wrobel Bozena B. , Zada Gabriel
Published: May 2021

OBJECTIVE

Internal carotid artery injury (ICAI) is a rare, life-threatening complication of endoscopic endonasal approaches that will be encountered by most skull base neurosurgeons and otolaryngologists. Rates of surgical proficiency for managing ICAI are not known, and the role of simulation to improve performance has not been studied on a nationwide scale.

METHODS

Attending and resident neurosurgery and otorhinolaryngology surgeons (n = 177) were recruited from multicenter regional and national training courses to assess training outcomes and validity at scale of a prospective educational intervention to improve surgeon technical skills using a previously validated, perfused human cadaveric simulator. Participants attempted an initial trial (T1) of simulated ICAI control using their preferred technique. An educational intervention including personalized instruction was performed. Participants attempted a second trial (T2). Task success (dichotomous), time to hemostasis (TTH), estimated blood loss (EBL), and surgeon heart rate were measured.

RESULTS

Participant rating scales confirmed that the simulation retained face and construct validity across eight instructional settings. Trial success (ICAI control) improved from 56% in T1 to 90% in T2 (p < 0.0001). EBL and TTH decreased by 37% and 38%, respectively (p < 0.0001). Postintervention resident surgeon performance (TTH, EBL, and success rate) was superior to preintervention attending surgeon performance. The most improved quartile of participants achieved 62% improvement in TTH and 73% improvement in EBL, with trial success improvement from 25.6% in T1 to 100% in T2 (p < 0.0001). Baseline surgeon confidence was uncorrelated with T1 success, while posttraining confidence correlated with T2 success. Tachycardia was measured in 57% of surgeon participants, but was attenuated during T2, consistent with development of resiliency.

CONCLUSIONS

Prior to training, many attending and most resident surgeons could not manage the rare, life-threatening intraoperative complication of ICAI. A simulated educational intervention significantly improved surgeon performance and remained valid when deployed at scale. Simulation also promoted the development of favorable cognitive skills (accurate perception of skill and resiliency). Rare, life-threatening intraoperative complications may be optimal targets for educational interventions using surgical simulation.
Does Online Education Support High Impact Educational Practices (HIEPs)?
Authors: Alenezi Majed
Published: May 2021

With the advancement of information technologies, the digitalisation of education has taken place in the form of High Impact Educational Practices (HIEPs). However, the COVID-19 outbreak in 2020 led to transition from traditional education to online education. However, while online education tools serve different educational purposes they are still associated with challenges like income inequalities, lack of technical expertise, or limited availability of resources, which tend to hamper HIEPs effectiveness in higher education. Thus, this study aims to determine the impact of using online educational tools on developing HIEPs in higher educational institutions. Empirical examination of (220) respondents from the Northern Border University (NBU) showed the role of online education in providing better understanding of information or better communication facility. Examination of online education role in supporting effectiveness of implementing HIEPs stated that situational factors, institutional factors, and dispositional factors of online education motivate students and faculty members, thus contributing to effectiveness in HIEPs implementation.
Relation of Obesity and Hypertension Among Elderly Karbis of Karbi Anglong, Assam
Authors: Sarmah Chandana
Published: May 2021

Worldwide there is increasing incidence of obesity. Obesity and hypertension are interrelated and result from changes in body composition and lifestyle factors concomitant to age. The present study examines the prevalence and relation of obesity and hypertension among elderly Karbis following a traditional way of life in the hill district of Karbi Anglong, Assam.The sample of the study consists of 335 male and female elderly (60 years and above) Karbis. Whole body obesity and abdominal obesity are assessed from anthropometric variables, indices and fat percentage. Hypertension is categorised according to the WHO classification of systolic and diastolic blood pressure used in estimating risk for metabolic syndrome.Prevalence of obesity by fat percentage is higher. Abdominal obesity and hypertension prevalence is higher in elderly female in comparison to elderly male. Hypertension prevalence is influenced significantly by fat percentage in both male and female elderly and by Waist Circumference in male elderly.
THE ANALYSIS OF THE AMBIVALENCE IN THE RELATIONSHIP BETWEEN GONERIL AND REGAN, AND CORDELIA AND LEAR IN KING LEAR, THE TRAGEDY PLAY BY WILLIAM SHAKESPEARE
Authors: Brkić Jelena
Published: May 2021

The paper aims to analyze the quality and nature of the ambivalence in the relationship between Regan and Goneril and, on the other hand, between Cordelia and Lear in the tragedy King Lear by William Shakespeare. Our major focus in on the first relationship. In this paper, we use graphs in accordance with the concept of presenting drama structures based on the idea of Franco Moretti. Since our intention is to point out the emotional nuances in the characters' relationships, in addition to the graphs that are in line with Moretti's distant reading, we also apply close reading and the psychoanalytic approach accompanied by the affective turn. The analysis confirmes the importance of the emotional nature and motivation in relationships between characters and the fact that we can and sometimes have to look for the causes for certain affective and emotional states in ahistorical situations. Also, the analysis shows that the visual presentation of the characters' relationships through nodes and edges can contribute to the recognition of emotional and verbal nuances in relationships, and sometimes nuances themselves opens the door for some new research, questions and discussions.
THE MOTHERHOOD CONTINENT AS A WRITING SPACE IN THE WORKS OF JASMINA TEŠANOVIĆ
Authors: Omeragić Merima
Published: May 2021

The phenomenon of motherhood is a challenging focus for research in the feminist literary theory/critique. The motherhood continent as a controversial point of contention in the society has become (or remains) a polemicized field between the traditionalism, critical, essentialist feminism and epistemology. Advocating for the deconstruction of social postulates of patriarchy starts with a revision of the positive connotations of motherhood, demonization of abortion/birth control, and the right to birth self-determination. In the struggle for power and control at the waning of matriarchy, the androcentric order established the purpose, model and objectives of motherhood. The examination in this work destabilizes elements of motherhood in A Women's Book, The Mermaids, Matrimonium, and Nefertiti Was Here. The objective of this work is to deconstruct the concept of motherhood that is present in our paternal/patriarchal traditions by denouncing the harmful and deeply rooted stereotypes. Simultaneously the work exposes and highlights the need for affirmation of authentic feminine legacy, elucidates aspects of the mother daughter relationship, and promotes the accomplishments of regional literature. In this scientific approach to the phenomenon of motherhood, the work makes use of such theoretical concepts as: ideology of intensive motherhood, creation of body language and women's writing, motherly instinct, maternal ideology, matriarchy and mythology, the black continent, identification with the mother, as well as the mother-daughter relationship, the child's belonging, motherhood and non-motherhood and abortion-birth sterility. The inclusion of these themes in the narratives is an indicative question of the subjective affirmative experience of motherhood, where we find transcendental impulses for generating women's language and creation, which juxtapose ideological norms, intensity of motherhood and achieve autonomy in literary creation.
RADOMIR KONSTANTINOVIĆ AND RADIO DRAMA
Authors: Vasić Rakočević Branislava V.
Published: May 2021

This paper begins with an overview of literary work of Radomir Konstantinović. The experimental character of his novels demonstrates the specificity of his literary modus operandi, as a unique phenomenon in Serbian literary scene during the fifth decade of the 20th century. His work will mark a turning point in the transition from modernism to postmodernism. His radio dramas, as well, represent a very specific part of his work mostly due to historical position of this genre. Since his radio dramas are first fully published in 2019. this paper traces a path for further research in this area.
THE LAST LETTERS OF JACOPO ORTIS IN EUROPEAN CONTEXT – THE FIRST EPISTOLARY NOVEL OF THE ITALIAN LITERARY TRADITION
Authors: Jauković Desanka
Published: May 2021

The subject of this paper is the analysis of the first epistolary novel of the Italian literary tradition, The Last Letters of Jacopo Ortis by Ugo Foscolo, work which, thanks to its polyvalent character, both in content and form, occupies a significant place in the rich European literary context. The genre debut of the Italian literary tradition is positioned in a very complex literary panorama in the beginning of the 19th century, as a follower of Rousseau's The New Eloise, Richardson's Pamela, and above all Goethe's The Sorrows of Young Werther, a work that is its closest European reference point in terms of composition and content. The polyvalent philosophical and artistic character of Foscolo's novel, its content stratification that reflects not only the intimate confession of the individual, but also the collective dilemmas of the then still ununited Italy in the complex cultural-historical mosaic of Europe of that time, however, are not in artistic collision with the unquestionable thematic and formal closeness between Foscolo's novel and its models in the European context - they only testify in a unique way, in a strong metatextual dialogue, complementary to the universal literary-ideological value of The Last Letters of Jacopo Ortis.
Pengaruh Corporate Governance dan Women on Board Terhadap Kinerja Perusahaan Sub Sektor Kosmetik Terdaftar di BEI Tahun 2015-2019
Authors: Saragi Mayang Sari , Siagian Valentine
Published: May 2021

In this study, the author aims to see the influence between Corporate Governance and Women on Board on the Financial Performance of the Cosmetics sub-sector companies listed on the Indonesia Stock Exchange in 2015-2019. The data used in this study are secondary data taken from the financial statements of cosmetic companies listed on the Indonesia Stock Exchange with the research sample of 30 cosmetic companies. In this study, corporate governance with an indicator of the proportion of independent commissioners and women on board with an indicator of the proportion of female commissioners as an independent variable, company performance as a dependent variable using an indicator of return on assets. Descriptive analysis techniques, correlation coefficient and determination coefficient tests were carried out to analyze the data. The results show that corporate governance has a significant effect on company performance. It was also found that women on board had a significant effect on the firm performance of a cosmetic company listed on the Indonesia Stock Exchange in 2015-2019.
Orçamento Público: dez anos de produção científica no congresso ANPCONT
Authors: Dombroski Luciane , Castro Marcos de
Published: May 2021

Este artigo analisou as características da produção científica sobre o tema orçamento público nos Congressos da Associação Nacional dos Programas de Pós-Graduação em Ciências Contábeis – ANPCONT no período de 2007 a 2016. Por meio de análise de conteúdo, o presente estudo identificou 64 artigos dispostos nas áreas temáticas de Controladoria e Contabilidade Gerencial (CCG), Contabilidade para Usuários Externos (CUE) e Controladoria e Contabilidade Aplicada ao Setor Público e ao Terceiro Setor (CPT), sendo que 60,06% dos trabalhos pertenciam ao período de 2007 a 2014 e estavam dispostos nas áreas de CCG e de CUE. No entanto, com a criação de uma área específica para o setor público em 2015, o número de estudos aumentou nos 2 últimos anos resultando em 35,94% dos trabalhos analisados. Em relação as características dos estudos analisados, a presente pesquisa revelou uma grande diversidade de assuntos discutidos nos artigos, sendo os mais sobressalientes: avaliação da eficiência em 7 trabalhos, convergência das Normas Brasileiras de Contabilidade Aplicadas ao Setor Público em 6 artigos, gasto público, Lei de Responsabilidade Fiscal e transparência em 5 estudos cada e regime de competência no setor público em 4 pesquisas. No tocante a característica autoria, esta pesquisa identificou 146 autores diferentes, sendo que 16 deles produziram 2 trabalhos, 6 produziram 3 artigos e 2 possuem coautoria em 4 estudos ao longo dos 10 anos de análise. Em relação a característica natureza das pesquisas, a presente pesquisa evidenciou que a maioria dos estudos, cerca de 67,2%, eram de natureza quantitativa, 25% eram estudos qualitativos e 7,80% pesquisas eram tanto qualitativas quanto quantitativas.
Bases Da Cultura Hindu: As Escolas Filosóficas E Sua Contribuição Para Espiritualidade Mundial
Authors: Mattos Tatiana Morita Nobre , Gama Uberto Afonso Albuquerque da
Published: May 2021

A Cultura Hindu é uma das mais antigas e completas estruturas filosóficas com finalidade espiritualista formuladas na história da humanidade. Reconhecida por sua profundidade, complexidade e amplitude de raciocínio, a qual virtuosamente associa a raiz científica à assuntos espirituais em explanações sobre a manifestação e a Realidade divina. Este artigo, tem por objetivo geral, apresentar as bases nas quais este sistema filosófico-cultural, e sua estrutura de pensamento, se fundamentou, e, por objetivos específicos, demonstrar como contribuiu para a formulação das principais religiões e filosofias do mundo, que visam auxiliar o homem a reencontrar a sua verdadeira natureza. Como metodologia, realizou-se uma pesquisa bibliográfica a qual abrangeu tanto autores ocidentais, pesquisadores da cultura e filosofia do Oriente, como autores orientais, renomados por sua explanação acerca dos estudos da tradição hindu. Constatou-se que os trabalhos que explanam sobre a influência da antiga estrutura de pensamento filosófico e científico oriental, especialmente da tradição hindu, apresentam a profundidade e a dedicação que este tema requer e evidencia a necessidade de continuidade e ampliação do estudo realizado.
ПЕРСПЕКТИВИ ВИКОРИСТАННЯ СУЧАСНИХ МЕХАНІЗМІВ ФІНАНСУВАННЯ БУДІВНИЦТВА
Authors: Івахненко Ірина
Published: May 2021

В сучасних умовах будівництво набуває все більшого значення – зростає кількість населення, а і разом з ним попит на житло, розвиваються міста, з’являється потреба в нових інфраструктурних проектах. Всі ці фактори сприяють збільшенню ролі будівництва у розвитку економіки. Однак для збільшення об’ємів будівництва, його якості для учасників будівельного ринку існує ціла низка перешкод. Однією із таких є залучення значних обсягів фінансування на реалізацію великих будівельних, інфраструктурних проектів. Вирішення проблеми фінансування будівництва дозволить більш якісно та ефективно вибудовувати стратегії залучення коштів в будівництво. Стаття присвячена визначенню основних способів і механізмів фінансування будівництва, аналізу будівельної галузі України та її фінансування, виявленню основних проблеми фінансування будівництва на даному етапі. В статті визначено основні проблеми фінансування будівництва в Україні такі як: низький рівень платоспроможного попиту серед населення на нерухомість через незадовільний рівень доходів населення. Запропоновано шляхи вирішення проблем фінансування будівництва, серед них: загальне підвищення рівня доходів населення, розвиток іпотечного житлового кредитування населення, запровадження та підтримка державних програм із забезпечення населення житло. Ці заходи можуть сприяти зростанню платоспроможного попиту серед населення, а отже і зростання фінансування будівництва. Запропоновані заходи щодо покращення інвестування в будівництво: зменшення податків на підприємства будівельної галузі – такий захід варто застосовувати стосовно підприємств, що займаються будівництвом важливих об’єктів або об’єктів «зеленої» енергетики; створити рівні умови для конкуренції, щоб усі підприємства «грали за одними правилами»; зменшити корупційну складову в будівельній галузі; спрямовувати інвестиції у пріоритетні та високоефективні будівельні проекти. Визначено, що важливим заходом для залучення інвестицій в будівництво стане підняття іміджу будівельних компаній шляхом використання прогресивних та сучасних матеріалів при будівництві, відкритої комунікації забудовника зі своїми клієнтами, поваги до місця будівництва, обслуговування об’єкту будівництва навіть після здачі його в експлуатацію, що сприятиме зацікавленості потенційних інвесторів у будівництві.
ВПЛИВ БІЗНЕС-РИЗИКІВ НА МЕНЕДЖМЕНТ ОРГАНІЗАЦІЙ
Authors: Коробка Світлана
Published: May 2021

Істотним чинником ризику у сучасних умовах є тенденція до глобалізації економіки. Більшість проблем, пов'язаних з управлінням ризиком, у сучасних умовах можна вирішити доволі оперативно за допомогою підвищення стратегічної значущості ризику-менеджменту на рівні підприємств, веденням нових координуючих механізмів, що дають компаніям змогу працювати в одному напрямку, не відхиляючись від вказаної траєкторії. Бізнес-ризик, як поняття зазнає постійних змін, наповнюється додатковим змістом та набуває нових видів. Управління бізнес-ризиками в менеджменті організацій є запорукою його прибутковості та раціонального розвитку. На результати підприємницької діяльності мають вплив конкурентні відносини між суб’єктами господарювання, які це більше посилюють бізнес-ризики в результаті своєї трансформації. Все це у своїй сукупності підвищує необхідність врахування бізнес-ризиків з якими зустрічаються підприємці і чинником розвитку його в цілому та кожної організації зокрема. Перспективність подальшого дослідження, полягає в тому що необхідно розробити дієві інструменти, які б одночасно попереджали підприємців про ймовірність виникнення ризико-формуючих подій і допомагав приймати рішення управління ризиками.
ПІДГОТОВКА ТУРИСТИЧНИХ КАДРІВ
Authors: Лук’янець Алла
Published: May 2021

У статті розглянуто сучасний стан підготовки фахівців туристичної сфери в Україні. Публікація актуалізує питання кваліфікованої підготовки фахівців сфери туризму. Робота містить огляд основних вимог та критеріїв, що постають перед працівником туристичної індустрії. У статті подано програмні напрямки підготовки фахівців сфери туризму та обов’язкові компоненти, що повинна включати професійна підготовка працівників туризму у вузах. Виявлено основну проблему підготовки туристичних кадрів: попри великий обсяг теоретичних знань, випускникам вузів критично не вистачає практичних навичок. Підсумовуючи, можна сказати, що в Україні, при підготовці туристичних кадрів необхідно створити більш тісний зв'язок між навчальними закладами, де відбувається підготовка фахівців туризму та підприємствами цієї сфери, оскільки обидві сторони зацікавлені у якісній підготовці фахівців з туризму.
Synthesis and Rheological Properties of Magnetic Chitosan Hydrogel
Authors: Ikhaddalene Soumia , Zibouche Fatima , Ponton Alain , Irekti Amar , Carn Florent
Published: May 2021

The aim of the present work is first to synthesis a magnetic chitosan hydrogel (chitosan ferrogel) using the blending method and second to study it rheological behavior. Magnetic components ( maghemite particles γ-Fe2O3 ) were synthesized via a simple chemical co-precipitation route also called Massart's procedure. Before being dispersed in chitosan network, γ-Fe2O3 particles were covered with a cationic polyelectrolyte (Polydiallyldimethylammonium chloride; PDADMAC) and the exact quantity required to cover the entire surface of maghemite particles was determined by Electrophoretic mobility. The successful functionalization of maghemite particles was confirmed by zeta potential measurement. The prepared ferrogel was gelified using glyoxal as crosslinking agent. The effect of continuous magnetic field on rheological properties of the elaborated ferrogel was studied, under controlled temperature before and after the gelation process, using a rotating rheometer fitted with a new magneto-rheological cell. Moreover the influence of iron oxide content on the gelation time of magnetic hydrogel was studied by comparing two ferrogels with different maghemite particles content. Flow and viscoelastic measurements showed that applying magnetic field facilitates the formation of a new structure (column-like arrangements), which was confirmed by in situ optical microscopic observation. Kinetic study was investigated by mechanical spectroscopy and demonstrates that the gelation time depends on both iron oxides content and magnetic field.
Dialogue on Posthuman Life, Death and COVID-19
Authors: Ferrando Francesca , Datta Asijit
Published: May 2021

This interview between Francesca Ferrando (New York University) and Asijit Datta (University of Calcutta) is an extended and exhaustive effort to weigh the pressing concerns of posthuman life, death, and philosophy in times of the Covid-19 pandemic. Philosophical discourse on matters related to dualism, humanism, anthropocentrism, during a phase when exposed human bodies are susceptible to a deadly, mutating virus itself, warrants some paradoxical attention. There has never been a more suitable age and a period to discuss the onto-epistemological anxieties against the background of biotechnological advancements. Akin to an inverse ouroboros, the latest medical equipment or a favourable vaccine for diseases is part of the reparation process undertaken to balance out the damage perpetrated by capitalism. Questions from the interviewer traverse topics involving the Anthropocene, non-human animals/others, genetic mutations, ethnic crises, ethical response towards the dead, posthumanism as spiritualism, and the posthuman multiverse. The conversation is initiated by Dr. Ferrando’s apposite response to the critical and desperate epoch facing the sixth mass extinction; she urges humans to recognize themselves as the most significant geological force impacting and contaminating the planet. The talk then shifts to the need for a harmonious ecological community and behavioural and dietary awareness of posthumanists. A major agitation in the first days of the compulsory lockdown in India had been the return of the migrant labourers and a reverse victim blaming to steer away attention from the failures of governmental policies and its impulsive decisions. Professor Ferrando rightly observes these as emanations from problems in humanization and socialization techniques and our collective negligence towards plurality. The Heideggerian understanding of technology as a revelation and Ferrando’s attachment of the concept of Brahman from the Hindu tradition bring the readers to her seminal book, Philosophical Posthumanism (2019). Spiritualism, Ferrando clarifies, is connected to post-dualism and assists in acknowledging multi-layered alterity and pluralism. Ferrando’s reply to Donna Haraway’s assertion of humans as compost conjoins her with Colebrook’s authentic human actions vis-à-vis the immediacy of extinction. Towards the end of the interview, Ferrando and Datta examine and explore the politicization of Covid deaths, mass burials, the hiding of data by governmental agencies, and the gravity of incomplete mourning as a result of these. The exchange concludes with a philosophical investigation into Nietzsche’s eternal return and a rhizomatic multiverse. Ferrando believes that the possibility that we are all networks and strings birthing multiple universes as we tread and vibrate along must propel us to act in ways that are more ethical, ecological, and interrelatonal.
Improved outcomes of high-risk relapsed Hodgkin lymphoma patients after high-dose chemotherapy: a 15-year analysis
Authors: Nieto Yago , Gruschkus Stephen , Valdez Benigno C. , Jones Roy B. , Anderlini Paolo , Hosing Chitra , Popat Uday , Qazilbash Muzaffar , Kebriaei Partow , Alousi Amin , Saini Neeraj , Srour Samer , Rezvani Katayoun , Ramdial Jeremy , Barnett Melissa , Gulbis Alison , Shigle Terri Lynn , Ahmed Sairah , Iyer Swaminathan , Lee Hun , Nair Ranjit , Parmar Simrit , Steiner Raphael , Dabaja Bouthaina , Pinnix Chelsea , Gunther Jillian , Cuglievan Branko , Mahadeo Kris , Khazal Sajad , Chuang Hubert , Champlin Richard , Shpall Elizabeth J. , Andersson Borje S.
Published: May 2021

High-dose chemotherapy and autologous stem-cell transplant (HDC/ASCT) is standard treatment for chemosensitive relapsed classical Hodgkin lymphoma, although outcomes of high-risk relapse (HRR) patients remain suboptimal. We retrospectively analyzed all HRR classical Hodgkin lymphoma patients treated with HDC/ASCT at our institution between 01/01/2005 and 12/31/2019. HRR criteria included primary refractory disease/relapse within 1 year, extranodal extension, B symptoms, requiring more than one salvage line, or positron emission tomography (PET)-positive disease at ASCT. All patients met the same ASCT eligibility criteria. We treated 501 patients with BEAM (n=146), busulphan/melphalan (BuMel) (n=38), gemcitabine( Gem)/BuMel (n=189) and vorinostat/Gem/BuMel (n=128). The Gem/BuMel and vorinostat/Gem/BuMel cohorts had more HRR criteria and more patients with PET-positive disease at ASCT. Treatment with brentuximab vedotin (BV) or anti-PD1 prior to ASCT, PET-negative disease at ASCT, and maintenance BV increased over time. BEAM and BuMel predominated in earlier years (2005-2007), GemBuMel and BEAM in middle years (2008-2015), and vorinostat/GemBuMel and BEAM in later years (2016-2019). The median follow-up is 50 months (range, 6-186). Outcomes improved over time, with 2-year progressionfree survival (PFS)/overall survival (OS) rates of 58%/82% (2005-2007), 59%/83% (2008-2011), 71%/94% (2012-2015) and 86%/99% (2016- 2019) (P<0.0001). Five-year PFS/OS rates were 72%/87% after vorinostat/ GemBuMel, 55%/75% after GemBuMel, 45%/61% after BEAM, and 39%/57% after BuMel (PFS: P=0.0003; OS: P<0.0001). These differences persisted within the PET-negative and PET-positive subgroups. Prior BV and vorinostat/GemBuMel were independent predictors of more favorable outcome, whereas primary refractory disease, ≥2 salvage lines, bulky relapse, B symptoms and PET-positivity at ASCT correlated independently with unfavorable outcomes. In conclusion, post-HDC/ASCT outcomes of patients with HRR classic Hodgkin lymphoma have improved over the last 15 years. Pre-ASCT BV treatment and optimized synergistic HDC (vorinostat/GemBuMel) were associated with this improvement.
DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome
Authors: Todoerti Katia , Ronchetti Domenica , Favasuli Vanessa , Maura Francesco , Morabito Fortunato , Bolli Niccolò , Taiana Elisa , Neri Antonino
Published: May 2021

DIS3 gene mutations occur in roughly 10% of patients with multiple myeloma (MM); furthermore, DIS3 expression can be affected by monosomy 13 and del(13q), which occur in approximately 40% of MM cases. Despite several reports on the prevalence of DIS3 mutations, their contribution to the pathobiology of MM remains largely unknown. We took advantage of the large public CoMMpass dataset to investigate the spectrum of DIS3 mutations in MM and its impact on the transcriptome and clinical outcome. We found that the clinical relevance of DIS3 mutations strictly depended on the co-occurrence of del(13q). In particular, bi-allelic DIS3 lesions significantly affected progression-free survival, independently of other predictors of poor clinical outcome, while mono-allelic events mostly affected overall survival. As expected, DIS3 mutations affect the MM transcriptome involving cellular processes and signaling pathways associated with RNA metabolism, and the deregulation of a large number of long non-coding RNA, among which we identified five distinct transcripts as independent predictors of poorer overall survival and nine of worse progression-free survival, with two (AC015982.2 and AL445228.3) predicting both unfavorable outcomes. These findings strongly prompt further studies investigating the relevance of these long non-coding RNA in MM.