bluuebunny/crossref_metadata_2025 huggingface dataset:
MEDICAL AND PSYCHOLOGICAL ASPECTS OF SAFETY AND ADAPTATION OF MILITARY PERSONNEL TO EXTREME CONDITIONS
Authors: Prykhodko Ihor I. , Bielai Serhii V. , Hrynzovskyi Anatolii M. , Zhelaho Anatolii М. , Hodlevskyi Serhii O. , Kalashchenko Svitlana I.
Published: October 2020

The aim: To determine the dynamics of adaptation resources and the level of psychological safety of the personality in service members of the National Guard of Ukraine who participated in combat operations in the East of Ukraine.
Materials and methods: To determine the peculiarities of military personnel adaptation to the combat activity, the “Adaptability-200” and “Disdaptability-45” methodologies were used. To determine the level of psychological safety of combatants we used “Diagnosis of psychological safety personality” and “Express diagnosis of psychological safety personality” Methodologies. The study was carried out during 2017, with 163 military participating.
Results: Being 2-3 weeks in combat conditions, 54% service members revealed high, 32% – average level of adaptability, and in 14% of them signs of non-adaptability were detected. The data of adaptation resources of combatants correlates with the results of diagnostics of psychological safety of personality: in 43% of them high level, 42% – average and 15% – low level of psychological safety were revealed.
Conclusions: The data obtained in the absolute majority of service members (86%) shows a good adaptability to combat conditions, and allows predicting adequate response to extreme conditions, high probability of preserving of the mental health and disability after the influence of vital factors.
PREVALENCE OF ROOT FILLED TEETH IN AN ADULT POPULATION (LVIV, UKRAINE) FOUND ON DIGITAL PANORAMIC RADIOGRAPHS
Authors: Dydyk Nataliya , Hrynyshyn Olha
Published: October 2020

The aim of this study was to determine the frequency of endodontic treatment in an adult Ukrainian population in relation to the age and its distribution depending on the type of the teeth.
Materials and methods: A total of 435 digital panoramic radiographs of adults (aged 18 to 72 years) were examined. A tooth was qualified as root filled (endodontically treated), if radiopaque root-filling material was determined in the pulp chamber and/or in the root canals. Pearson’s chi-squared test (χ2) and Spearman’s rank correlation were applied for data analysis.
Results: It was revealed that 82.5% of patients had previously received endodontic treatment of the teeth. The overall percentage of root filled teeth in adult dentition is 12.08%. The analysis of the rate of endodontically treated teeth in different age groups identified an increasing of treated teeth with age – from 5.2% in the youngest cohort (18-19 years old) to 24.9% in the oldest cohorts. It was revealed that 822 teeth (14.2%) on maxilla and 569 (9.9%) on the mandible were endodontically treated. Most often root filled teeth were first mandibular molars (39.3%), first maxillary molars (26.7%) and second maxillary premolars (20.4%). Much lower rate of endodontic treatment were considered in lower mandibular incisors and canines (0.7%, 0.9% and 1.5% respectively).
Conclusions: A total of 82.5% examined adults had one or more endodontically treated teeth in this study. The obtained results prove the necessity of prevention of caries with special emphasis on the first maxillary and mandibular molars, and maxillary second premolars, which have significantly higher frequency of root canal treatment in comparison to other teeth groups.
DYNAMICS OF FUNCTIONAL CONDITION SEEDMANS AND LIVER IN MEN WITH INFERTILITY UNDER THE INFLUENCE OF ARGININ THERAPY WITH THE COMPLEX OF L-CARNITIN AND BETAINЕ
Authors: Bondarenko Volodymyr O. , Minukhin Andriy S. , Skornyakov Evgeniy I. , Kononenko Nadiia M. , Ostapets Maryna O.
Published: October 2020

The aim of this work was to study the hormonal status androgen-dependent indicators of the ejaculate, spermatogram parameters and liver transaminases in the blood of the infertile males for the treatment of arginine, carnitine and betaine. Materials and methods: The parameters of spermograms, the levels of testosterone, estradiol, alanine aminotransferase and aspartate aminotransferase in the blood, and concentration of fructose in the ejaculate of 31 men with idiopathic pathospermia before and after using the L-Betargin, which contains 1 gram of arginine, 300 mg of L-carnitine and 1 gram of betaine. Results: It is shown that after treatment there is an increase of sperm concentration and their motility, increase the level of fructose in the ejaculate. It is established that the positive effect on spermatogenesis, L-Betargin associated with activation of endocrine function of the testes, improving the androgen-estrogen balance and functional state of the liver in men with infertility. Conclusions: The use of L-Betargin for a month in men with idiopathic pathospermia leads to an increase in the concentration of sperm and increase their motility, while normalizing all parameters of the spermogram.
EFFECT OF LOCAL UV RADIATION ON THE MORPHOFUNCTIONAL STATE OF THE SKIN OF GUINEA PIGS IN EARLY AND REMOTE PERIODS AFTER IRRADIATION
Authors: Zvyagintseva Tetyana V. , Myronchenko Svitlana I. , Kytsiuk Nataliia I. , Naumova Olga V.
Published: October 2020

The aim is to establish the features of morphological and morphometric changes in the skin of guinea pigs in erythemal, early post-erythemal and late post-erythemic periods after local ultraviolet irradiation.
Materials and methods: Studies were conducted on 54 albino guinea pigs weighing 400-500 g. Ultraviolet erythema was caused by irradiation in 1 minimum erythemal dose. The control group included intact guinea pigs. After 2, 4 hours, on the 3rd, 8th, 15th, 21st, 28th day, the fragments of the irradiated skin were investigated using histochemical and morphometric methods.
Results: After 2, 4 hours after irradiation, dyscirculatory changes in the skin develop. By the 3rd day of the experiment a morphological picture of acute inflammation in the epidermis and dermis develops, apoptotic keratinocytes appear (sunburn cells), which is accompanied by thickening of the epidermis and an increase in the density of fibroblasts. By the 8th day proliferative-hyperplastic and degenerative changes begin to prevail, including dystrophic nature, the thickness of the epidermis and the density of fibroblasts reach a maximum. In the long term, on the 15-28th day, dystrophic changes of the epidermis, dyskeratosis, changes in the number and structure of elastic fibers with an increase in uneven fibrosis, collagenization processes and the development of sclerotic changes, as well as a significant thickening of the epidermis, an increase in the density of fibroblasts are observed.
Conclusions: The data obtained indicate pronounced morphofunctional changes in the skin in the zone of local ultraviolet irradiation observed throughout the entire observation period.
ANEMIA IN PATIENTS WITH ANKYLOSING SPONDYLITIS, ASSOCIATION WITH THE ACTIVITY OF THE INFLAMMATORY PROCESS AND THE SEVERITY OF THE DISEASE
Authors: Zviahina Oksana V. , Shevchuk Sergii V. , Kuvikova Inna P. , Segeda Iuliia S.
Published: October 2020

The aim: To estimate the prevalence of anemia in patients with ankylosing spondylitis, major pathogenetic variants and their relationship with the activity of the inflammatory process and the severity of the disease.
Materials and methods: 118 patients with ankylosing spondylitis participated in the study, which performed hematologic, biochemical, immunological studies with general haemopoiesis and ferrokinetics parameters, plasma levels of CRP and IL-6.
Results: It was found that in Ukrainian population of patients with ankylosing spondylitis, 28.8% of patients has anemic syndrome. The anemia spectrum is represented by ACD (44.1%), ACD with iron deficiency (29.4%) and IDA (23.5%). It is shown that the severity of anemic syndrome increases with the increase of the stage of activity of the inflammatory process. The presence and severity of anemia are closely related to the severe course of the disease, evaluated by the BASDAI and ASDAS index, and laboratory markers of inflammation CRP and IL-6 of serum.
Conclusions: The obtained data is promising for the search of effective means of correction of anemic syndrome in patients with ankylosing spondylitis.
THE 5-YEAR DYNAMICS OF CARDIAC STRUCTURE AND FUNCTION IN PATIENTS WITH CORONARY ARTERY DISEASE AFTER MYOCARDIAL REVASCULARIZATION
Authors: Guta Roksolana R. , Radchenko Olena M. , Korolyuk Olga Ya.
Published: October 2020

The aim: To estimate the dynamics of echocardiographic parameters in patients with CAD within 5 years after revascularization.
Material and methods: 50 persons (males/females 39/11; mean age 59.9±9.3 years; STEMI 76%, non-STEMI 24%) were divided into two groups: n=38 after PCI with stenting (PCIwS); n=12 after CABG. Observation included regular echocardiography with LV myocardial mass (LVMM) and geometry estimation.
Results: Groups were comparable by age, co-morbidity, BP, heart rate and BMI. Significantly severe baseline LV hypertrophy (LVH) and left atrial enlargement (LAE) in group 2 explained by spread coronary atherosclerosis. Later progressive LAE (4.37±0.22 cm, P0-60<0.05) in group 1, and aortic/LV dilatation (+0.4/+1.0 cm, respectively, both P0-60<0.05) in group 2 developed. In two years LVMM index increased by 13.4/17.5% in groups 1/2, respectively. Normal geometry and concentric remodeling completely disappeared in 3/1.5 years after PCIwS/CABG, respectively.
Conclusions: Within the 1st year after revascularization, patients with CABG had more severe LVH. In 5 years after PCIwS the ratio between concentric/eccentric LVH was 2:1, whereas after CABG – 1:2.
DEVELOPMENT AND ANALYSIS OF DIAGNOSTIC CRITERIA FOR CREATION OF AN AUTOMATED COMPUTER SOFTWARE FOR PREDICTING THE COURSE AND INDIVIDUALIZING THE TREATMENT OF PATIENTS WITH ODONTOGENIC MAXILLARY SINUSITIS
Authors: Voloshan Olexsandr O. , Grigorov Sergey M. , Demyanyk Dmytro S.
Published: October 2020

The aim of our study was to create a database of the most informative diagnostic criteria for predicting the treatment results for various odontogenic maxillary sinusitis (OMS) forms using automated computer software.
Materials and methods: In order to select and assess the most informative diagnostic criteria for predicting the treatment results for various OMS forms, the total of 9 subject matter experts (SME) were included into the problem commission on the specialty “Dentistry”.
Results: After calculating the data obtained according to the method of Yana V. Nosova, the working group experts’ level of competency was M = 0. 90. This confirmed the group’s qualification, which further led to the approval of scoring coefficients, depending on the degree of a particular index importance. The basic and minor parameters in the subjective, objective, introscopic and laboratory data of OMS patients were identified.
Conclusions: The developed database of diagnostic criteria has formed the basis of an automated computer software for predicting the course and individualizing the patients’ treatment in odontogenic maxillary sinusitis.
PROBLEMS OF “CONTROLLED INFECTION”: PECULIARITIES OF MEASLES IN ADULTS IN IVANO-FRANKIVSK REGION
Authors: Pryshliak Oleksandra Ya. , Dykyi Bohdan M. , Matviiuk Olha Ya. , Boichuk Oleksandr P. , Prokopovych Mariana V. , Kobryn Taras Z. , Miziuk Ruslan M.
Published: October 2020

The aim: To study the clinical and epidemiological peculiarities of measles in adults according to the data of the Regional Clinical Infectious Disease Hospital in Ivano-Frankivsk, Ukraine. Materials and methods: The article analyzes the epidemiological and clinical features of 113 cases of measles among adults who undergone inpatient treatment in 2017-2018. The diagnosis was confirmed by the detection of antiviral Ig M antibodies. Determination of the genotype of the virus was performed in Regional WHO Reference Laboratory in Luxembourg. Results: The genotype of the measles virus was MVs/Cambridge GBR/5.16 D8 is circulating through the region territory. In 98.3% of adult patients a typical clinical picture of moderate severity was observed. Measles was accompanied by complications such as acute bronchitis (23.9%), reactive hepatitis (13.3%), reactive pancreatitis (10.6%) and pneumonia (7.1%). Сonclusions: The following epidemiological peculiarities in adult patients with measles: young people are mostly ill, urban residents are not vaccinated, partly vaccinated or with an unknown vaccine status. There was a change in the genotype of the virus of measles circulating in the Ivano-Frankivsk region: in 2012 genotype MVs/ManchesterGBR/10.09D4 was confirmed, now the genotype of the measles virus is MVS/ CambridgeGBR/5.16D8. In 98 (86.73%) patients was a typical clinical picture of the disease, of moderate severity. Among the complications of the disease were diagnosed: bronchitis and pneumonia (23.9% and 7.1% respectively), reactive hepatitis and reactive pancreatitis (13.3% and 10.6%).
PECULIAR FEATURES OF AORTIC WALL STRUCTURE AMONG CHILDREN WITH COARCTATION
Authors: Khapchenkova Daria S. , Senatorova Ganna S.
Published: October 2020

The aim of the study to evaluate the peculiarities of the aortic wall structure at the place of coarctation.
Materials and methods: Studying of the aortic sections removed during operative correction at the place of constriction. 10 children at the age between 1 to 6 months were undergone the operation. Intraoperative aortic biopsy specimens were observed in 10% neutral formalin. Histologic sections were prepared in a conventional way followed by staining them with hematoxylin-eosin.
Results: Histological examination in the areas of constriction revealed that the endothelium in all the preparations had poor expressiveness. The most significant changes were recorded in the middle layer of the aorta in the form of reduced development of elastic fibers, their fragmentation and chaotic arrangement. Angiomatosis with the formation of thin-layer small vessels by capillary type was found out. In all the preparations, areas of emptying of cells and fibers of the middle cover with the formation of cystic structures were revealed.
Conclusions: The histological examination has revealed changes in the structure of the aorta wall, which may indicate the systemic nature of the lesion and make it possible to consider coarctation of the aorta to be a manifestation of systemic vasculopathy. The above-mentioned facts determine the need for a more detailed examination of children with the specified pathology at different stages of observation.
PREDICTION OF THE DEVELOPMENT OF RETINAL MORPHOLOGICAL CHANGES AFTER PHACOEMULSIFICATION BASED ON THE STATE OF THE CYTOKINE PROFILE OF INTRAOCULAR FLUID
Authors: Bezkorovayna Iryna M. , Steblovska Iryna S. , Ryadnova Vita V. , Pera-Vasilchenko Anna V. , Voskresenska Liudmyla K. , Bezega Nina M.
Published: October 2020

The aim: To investigate the features of cytokine profile of intraocular fluid in patients undergoing cataract phacoemulsification and the effect of their level on the nature and frequency of early and late postoperative complications from the retina.
Materials and methods: The work involved 82 patients (82 eyes) with cataract during traditional phacoemulsification on the basis of Ophthalmology department of Poltava Regional Clinical Hospital. The intraocular fluid for the study, while performing phacoemulsification of the nucleus, was collected with a single insulin syringe through the paracentesis of the cornea in the volume of 0.3-0.4 ml for the examination of TNF-α and bFGF levels.
Results: It was found that the level of TNF-α intraocular fluid ranged from 1.11 pg / ml to 140.55 pg / ml; its average was 24.61 ± 5.43 pg / ml. When examining the level of bFGF in intraocular fluid, it ranged from 1.0 pg / ml to 12.54 pg / ml; its average was 3.33 ± 0.44 pg / ml.
Conclusions: Comparing the levels of the effect of TNF-α and bFGF of the intraocular fluid of patients with cataracts and morphological changes of the retina after phacoemulsification revealed a direct dependence of the level of these factors on the development of macular edema.
HEALTH STATUS OF CHILDREN POPULATION UNDER INFLUENCE OF THE CHEMICAL COMPOSITION OF DRINKING WATER
Authors: Hryhorenko Luibov V. , Bashmakov Dmytro G.
Published: October 2020

The aim: To study health status among the children in connection with a prolonged exposure of drinking water from decentralized systems.
Materials and methods: The prevalence rates of diseases among children of rural areas were studied according to the statistical reports in Dnipropetrovsk region health information center from 2008 to 2013 using statistical form № 12 (totally 220 reports). The distribution of rural areas in the region was based on the cluster analysis. The horizontal dendrogram showing similarity between the research areas in a multidimensional space. Cluster analysis includes 2 groups of rural districts in Dnipropetrovsk region.
Results: It is established that with increase of pH> 7.5-7.6 in water of decentralized systems decreased the prevalence in the majority of nosologies: diseases of the blood and hematopoietic organs (rS=0,331; p<0,001), musculoskeletal system (rS=-0,174; p<0,001), anemia (rS=-0,331; p<0,001), congenital anomalies (rS=-0,272; p=0,002) among children population.
Conclusions: Among those children, who consumed drinking water from wells with content of some essential trace elements on the limits of MPC: 71% did not suffer from chronic diseases of the circulatory system (Fe >0.144 mg/dm3); 59% did not suffer from the diseases of digestive system (Cu >0.089 mg/dm3), and 60% had no congenital abnormalities of circulatory system (Mn > 0.099 mg/dm3).
MODELS OF INDIVIDUAL LINEAR DIMENSIONS NECESSARY
FOR THE CONSTRUCTION OF THE CORRECT FORM OF DENTAL
ARCHES IN YOUNG MEN WITH A WIDE FACE, DEPENDING ON
THE FEATURES OF ODONTOMETRIC AND CEPHALOMETRIC
INDICATORS
Authors: Маrchenko Аlla V. , Shinkaruk-Dykovytska Mariya М. , Pozur Taras P. , Gunas Valery I. , Orlovskiy Volodymyr O.
Published: October 2020

The aim is development and analysis of regression models of linear dimensions necessary for the construction of the correct form of dental arches in young men with a wide
face, depending on the features of odontometric and cephalometric indicators.
Material and methods: Primary computed tomographic indices of tooth size and cephalometric parameters of 44 young men with normal occlusion were obtained from
the data bank of the National Pirogov Memorial Medical University, Vinnytsya. Face type was determined using the Garson morphological index. In licensed statistical package
“Statistica 6,0” developed regression models of linear dimensions necessary for the construction of the correct form of dental arches.
Results: As a result of researches, it is established that all 18 reliable models of the sizes used for construction of the correct form of dental arches, depending on peculiarities
of odontometric and cephalometric indices with a coefficient from 0.645 to 0.944 are constructed. Built models in adolescents with a broad face type more often include
odontometric than cephalometric indicators. The most commonly used odontometric indices are: the width of the crowns of the teeth in the mesio-distal and vestibulo-oral
directions, as well as the distance from the middle of the cutting edge to the apex of the root of the teeth in the vestibulo-oral direction.
Conclusions: In adolescents with a broad type of face with normal occlusion, all 18 possible reliable regression models of reproduction of the individual characteristics of the
dental arches of the upper and lower jaws were determined and analyzed.
BITTEN WOUNDS OF THE MAXILLOFACIAL AREA IN CHILDREN
Authors: Tkachenko Pavlo I. , Bilokon Serhii O. , Dolenko Olha B. , Korotych Nataliia M. , Popelo Yuliia V. , Bilokon Nataliia P.
Published: October 2020

The aim of the work is to determine the frequency, structure, features of clinical manifestations and treatment of bitten wounds of the face and neck in children of Poltava region.
Materials and methods: It has been analyzed 91 histories of disease of thematic patients undergone treatment at the Surgical Department of Pediatric town clinical hospital
of Poltava.
Results: In the structure of traumatic injuries of maxillofacial area in children 5.3% were patients with bitten wounds of the face and neck. Among the injured were children
of the age 7-12 years old (30.2%). In 74.7% of cases, the bites were complicated by acute inflammatory processes. Urban residents accounted for 71.8% of the total number of
cases, while rural residents accounted for 28.2%. Boys were injured by 53.6% and girls by 46.4%. Sharps (74.5%), punctures (19.3%) and lacerations (6.2%) differed in form.
The comprehensive treatment of patients with bitten maxillofacial area wounds was carried out according to the protocol of care.
Conclusions: The clinical picture and severity of bitten wounds of maxillofacial area in children have individual features, which are largely due to topographic and anatomical
localization of injuries.
The choice of the optimal variant of primary surgical treatment of wounds and the amount of surgery should be determined individually depending on the severity of the injury,
the time of injury. Special attention should be paid to normalization of psycho-emotional state of patients and prevention of scar formation.
PAIN AS LEADING SYNDROME OF THE SOMATOFORM DISORDERS
AT THE PEDIATRICS
Authors: Chernyshov Oleh V. , Zak Maksim U. , Shawlis Nataliia N. , Zhuk Svetlana V.
Published: October 2020

The aim: Study of somatoform vegetative dysfunction’ clinical features at adolescent age with a chronic pain (HA syndrome and AP syndrome), and also socially-psychological
factors of its formation too.
Materials and methods: There are 82 teenagers have been examined in this research: 48 girls (58,5 %) and 34 young men (41,5 %) at the age of 16 – 17 years. Research will
be done according to diagnostic criteria of ICD-10.
Results: An aetiological basis of HAS and APS are various somatoform disorder mostly at teenage age (70,8 % cases at girls and in 58,8 % – at young men). 32,2 % of the patients
had various neurotic disturbances with anxiety-depressive symptoms in a genesis of HAS and APS. Somatoform vegetative dysfunction – the most widespread reason of HAS and
APS development among teenagers. Among teenagers HAS cases (68,8 % – at girls, 58,8 % – at young men) essentially prevail over APS (31,2 and 41,2 % cases accordingly).
All adolescents had combine negative life events in their life. Girls felt psychotraumatic experience more strongly than young man. The greatest combine negative life experience
has been revealed in a subgroup of girls with HAS. The least influence of psychotraumatic factors was observed at young men with APS.
Consequently, SVD, accompanied by severe pain in adolescence – is pathogenic complex and combined mental disorders, requiring adequate psychopharmacological and
psychotherapeutic intervention.
Conclusions: Chronic stressful situations were experienced by each of the examined patients. Each of the teens noted combination of stress problems in their lives. The widespread
common problem among the examined adolescents was a sense of being overprotected by parents. Consequently, SVD, accompanied by severe pain in adolescence –is pathogenic
complex and combined mental disorders, requiring adequate psychopharmacological and psychotherapeutic intervention.
CLINICAL AND MICROBIOLOGICAL ASSESSMENT OF ROOT CANAL
DECONTAMINATION IN CHRONIC APICAL PERIODONTITIS USING
THE ULTRASOUND
Authors: Horlenko Irina M. , Gadzhula Nataliia G. , Cherepakha Olena L. , Kurdysh Larysa F. , Pylypiuk Olha Yu.
Published: October 2020

The aim: To study the effectiveness of chronic apical periodontitis treatment by the combined use of ultrasonic treatment of root canals and multicomponent antimicrobial gel
according to the results of clinical and microbiological researches.
Materials and methods: 64 patients with chronic apical periodontitis at the age of 18-56 years were treated. Patients were divided into two groups: the main and control. In
the main group the root canals of 36 teeth were sonicated in combination with multicomponent antimicrobial gel, in the control – 35 teeth were treated by a standard method.
The content of the root canals for microbiological studies was obtained before endodontic treatment and before permanent obturation. Frequency of content and number of
bacteria in the samples were evaluated.
Results: All samples before treatment were positive for the presence of variable bacterial flora, among which Staphylococcus epidermidis (43.9%), Enterococcus faecalis (37.9%), Streptococcus spp. (24.8%), Candida albicans (24.4%), Fusibacterium (9.4%) were the most dominant, their number was 7.4-4.8 lg CFU/ml. Repeated research after the proposed and standard method of root canal decontamination has shown a significant decrease in microflora. According to the data of clinical and microbiological examination, the method which was developed by us revealed a positive result in 86% of cases compared with 63% when treated by the standard method.
Conclusions: The effectiveness of a complex treatment method with combined use of the ultrasonic irrigation and multicomponent antimicrobial gel for root canals decontamination in chronic apical periodontitis is demonstrated. Significant reduction of microflora growth and destruction of microbial associations, good penetration of multicomponent antimicrobial gel into endodontic structures due to ultrasound compared with a standard method were achieved.
CONCEPTUAL DIRECTIONS IN ORGANIZATION OF MEDICAL
ASSISTANCE FOR CHILDREN IN THE CONDITIONS OF EDUCATION
Authors: Danylenko Georgii M. , Peresypkina Tetiana V. , Butenko Antonina I. , Peresypkina Anna M. , Holubnycha Halyna I. , Zinchuk Andrii M. , Zinchuk Olha G.
Published: October 2020

The aim of this work is: to define the Conceptual model of medical provision of children in educational institutions in modern conditions.
Materials and methods: analysis of data from a longitudinal study of children’s health; questionnaire of parents, teachers, heads of educational institutions on the volume
of medical support for students; questioning students’ lifestyle and social determinants of health.
Results: According to the study has determined the medical and social determinants which negative affect on health status of school age childrens; detected the most appropriate types of of school health services which based on the parents, medical and teachers opinion. The important also is monitoring of health status of children for develop of prevent measure for improove health status and forming of healthy lifestyle behavioral. Problematic issues to be addressed include: improving the legal framework on the competences and volumes of health care for pupils in educational institutions; material equipment; setting up a system for monitoring and analyzing the health status of students and educational groups, identifying health risk factors; establishing a continuous multimodal health-oriented system of student-oriented youth behavior.
Conclusions: The health status of students and the level of health-oriented behavior, the reform of the medical sector require introduction of an effective system of medical
support for students of organized groups, improving the system of preventive care for students, parents, which is presented in the Conceptual model.
ASSOCIATION BETWEEN EMOTIONAL-VOLITIONAL
DYSFUNCTION AND FEATURES OF AGGRESSION OR HOSTILITY
IN MENS WITH DIFFERENT FORMS OF SUBSTANCE ADDICTIONS:
A CROSS-SECTIONAL STUDY
Authors: Zhyvotovska Liliia V. , Boiko Dmytro I. , Kadzhaia Nataliia V. , Shkodina Anastasia D. , Demianenko Iryna V. , Borysenko Volodymyr V.
Published: October 2020

The aim: The research aim was to study features of emotional-volitional sphere and its association in mens with different forms of Substance Addictions.
Materials and methods: We examined 146 patients with alcohol and drug addictions using Toronto Alexithymia Scale, Zverkov-Eidmann`s questionnaire and Buss-Durkee
questionnaire.
Results: The study showed an increase in the overall level of alexithymia, a moderate level of aggressiveness and a sufficient level of volitional self-regulation without a significant
difference between the groups. The indirect correlation of “persistence” with the “general level of alexithymia”, “difficulty identifying feelings” and “physical aggression” in group 1
and at the same time the indirect correlation between “self-control” and “verbal aggression” and “volitional self-regulation” with “difficulty describing feelings” can be explained
by the opposite meaning of these concepts and phenomena themselves.However, it is interesting that the indicators “physical aggression” and “difficulty describing feelings”
in group 2 were significantly lower, but at the same time correlated with “general level of alexithymia” and “irritability”, respectively. On other hand in group 1 the indicator
“suspiciousness” is directly related to the “general level of alexithymia”, but its level is significantly lower in comparison with group 2.
Conclusions: The phenomenon of alexithymia is not only recorded in the clinical picture of patients with various forms of addiction, but can also induce the development of
manifestations of aggressiveness and hostility in them. Correction of alexithymia is necessary to understand the emotional state of these patients and choose the right approach
to their treatment and rehabilitation.
THE IMPACT OF OVERWEIGHT AND OBESITY ON THE QUALITY
OF LIFE IN CHILDREN WITH BRONCHIAL ASTHMA
Authors: Kupkina Anna V. , Volosovets Oleksandr P. , Kryvopustov Sergii P. , Prokhorova Marija P. , Mozyrska Olena V.
Published: October 2020

The aim is to investigate if the overweight (OW) and obesity (OB) impact on the quality of life (QOL) of children with bronchial asthma (BA).
Materials and methods: The study included 73 children aged 7 – 17, with moderate BA. Depending on the body mass index, patients were divided into the three clinical
groups: normal body weight (NW) – 30 children, OW – 28 children and OB – 15 children. QOL was conducted by the Pediatric Asthma Quality of Life Questionnaire (PAQLQ).
The statistical processing was carried out using the IBM SPSS Statistics Base (version 22) and EZR version 1.32. Results were considered statistically significant when p<0.05.
Results: Children with BA and OB had statistically lower QOL than children with BA and NW in all PAQLQ domains. The Kruskal-Wallis H-test revealed a statistically significant
difference between the different weight groups of children with BA both for the general QOL: H(2) = 37.51, p<0.001and for each rating scale separately. Pairwise comparisons
using Steel-Dwass test indicated that scores of NW were observed to be significantly different from those of OW and OB for rating Activity and Symptoms scales (p<0.001).
Conclusion: Comorbid OW and OB reduce the specific QOL of children with BA. In assessing the effectiveness of specific approaches to treating BA in children with OW and OB,
an assessment of the QOL of children should be added to the traditional common clinical and laboratory assessment.
COMPARATIVE QUALITY ASSESSMENT OF ROOT CANAL
PREPARATION WITH DIFFERENT SYSTEMS OF ENDODONTIC
INSTRUMENTS
Authors: Goray Maryna A. , Gadzhula Nataliia G. , Muntian Olena V. , Cherepakha Olena L. , Kurdysh Larysa F.
Published: October 2020

The aim: To compare the quality of root canal system preparation with the use of manual K-files, machine Protaper Universal and Silk files by in vitro studies.
Materials and methods: Root canals preparation in 45 extracted premolars was performed in three groups with 15 teeth in each with K-files, Protaper Universal and Silk
files. Transverse sections of the dental root were prepared. Histologically were assessed: amount of sawdust and predentin remaining, the purity degree of root canal walls.
Results: When calculating the sawdust amount at the distance of 3 mm from an apex, a high degree of contamination was observed in the manual K-file group: 53.3% versus
33.3% in the Protaper Universal group and against 20.0% in the Silk file group. The amount of predentin after root canal treatment with manual files reached 25-30%. At the
distance of 5 mm from the apex the root canals with high and medium purity degree were detected in 86.7% with Silk files and 80.0% with Protaper Universal files used. All
predentin was removed when working with Protaper Universal and Silk files.
Conclusions: In the histological sections of the root canals treated with K-files, the larger amount of dentine particles and predentin has been revealed than when using machine
tools. The largest amount of predentin and dentine were removed with Protaper Universal files. Silk endodontic system is better for treatment of the root canals dentine surface
in the apical area compared to Protaper Universal and K-files.
CLINICAL FEATURES OF ADJUSTMENT DISORDER IN INTERNALLY
DISPLACED WOMEN
Authors: Herasymenko Larysa O. , Isakov Rustam I. , Halchenko Alina V. , Kydon Pavlo V.
Published: October 2020

The aim: To study the clinical features of internally displaced women with adjustment disorders.
Materials and methods: Clinical features of internally displaced women with adjustment disorders are investigated. Comprehensive clinical psychopathological and
psychodiagnostic assessment of 58 women have been conducted, their medical history data have been analyzed.
Results: According to the analysis of the questionnaire severity of psychopathological symptoms prevalence of phobic anxiety, somatization with the presence of distress
were observed in internally displaced women. In the clinical presentation of psychopathological disorders, the following symptoms of anxiety-depressive syndrome complex
prevailed: mental fatigue 93.1 ± 3.9%; decrease in working capacity in 89.7 ± 4.2% of women; decrease in mood 79.3 ± 6.9%; anxiety 75.7 ± 3.8%; decrease in libido in 65.7 ±
4.9%; physical fatigue – 51.7 ± 4.4% of the examined.
Conclusions: Analysis of clinical and psychopathological symptoms of women with adjustment disorder indicates the dominance in the structure of symptoms of anxiety and
depressive symptoms in mixed and isolated forms. According to the analysis of the questionnaire of severity of psychopathological symptoms, in internally displaced women,
the prevalence of phobic anxiety, somatization with the presence of distress was observed.
PREVALENCE OF CHLAMYDIA-RELATED ORGANISMS WITH
ZOONOTIC POTENTIAL IN FARMS OF THE POLTAVA REGION
Authors: Zezekalo Viktoriya K. , Kulynych Serhii M. , Polishchuk Anatoliy А. , Kone Mokhamed S. , Avramenko Natalia О. , Vakulenko Yuliia V. , Chyzhanska Nataliia V.
Published: October 2020

The aim of our work was to survey private farms in the Poltava region on the prevalence of Chlamydia-like organisms Waddlia chondrophila and Parachlamydia acanthamoebae.
Materials and methods: The PCR research was conducted in 2018-2019 at the Institute of Pig Breeding and Аgro-industrial production of the NAAS. The study materials were 300
vaginal scrapings of cows and 28 samples of clinical material of pigs and boars with a suspicion of a chlamydial infection, which were selected at private farms in the Poltava region.
Results: Chlamydia-like bacteria Waddlia chrondophila DNA was detected in 132 (44%) samples taken from cows and 8 (28.6%) samples from pigs and boars. Parachlamydia
acanthamoebae DNA was not detected in pig samples. However, 43 (14.3%) clinical samples taken from cows were found to be Parachlamydia acanthamoebae – positive.
9 (3%) cows and 2 (7.14%) pigs turned out to be Chlamydia spp. – positive (the samples contained DNA of bacteria of the family Chlamydiaceae).
Сonclusions: Our data indicate a relatively high prevalence of Chlamydia-like bacteria in problematic as to chlamydial infection farms in the Poltava region. Chlamydial infection
carry a zoonotic threat, therefore it is necessary to observe safety and personal hygiene measures when working with animals. In addition, it is necessary to carry out periodic
screening among the population with reproductive disorders and in occupational risk groups, periodic monitoring in livestock farms, to avoid the consuming the unpasteurized
milk, and thermally unprocessed meat.
ADVERSE FACTORS THAT CAN AFFECT ON THE COURSE OF CHRONIC PARENCHIMATIC PAROTITIS IN CHILDREN
Authors: Tkachenko Pavlo I. , Bilokon Serhii O. , Popelo Yuliia V. , Lokhmatova Nataliia M. , Dolenko Olha B. , Korotych Nataliia M.
Published: October 2020

The aim: The study of the presence of disorders in the ante- and postnatal periods of development of children from 2 months to 15 years with chronic parenchimatic parotitis,
which may affect its course.
Materials and methods: It has been examined and treated 88 children, aged from 2 months to 15 years with chronic parenchimatic parotitis, and their mothers were interviewed,
who indicated the pathological course of pregnancy, childbirth and indicated the type of breastfeeding babbies. The scope of the survey included general, additional methods,
consultations by related specialists and statistical processing of results.
Results: 88 children with the exacerbation of chronic parenchimatic parotitis were examined (42 – (47%) with active course and 46 – (53%) with inactive). The exacerbation
occurred on the background of acute infectious processes or coincided with the exacerbation of one of the chronic diseases. The first manifestations occurred in spring (55%) and
autumn (36%) periods, 44% of children were hospitalized with other diagnoses. The presence of pathological conditions during pregnancy and birth defects in their mothers
were recorded more often 3,5 and 3,3 times, respectively, compared with control. 70% of children received mixed and artificial feeding and were more likely to become ill.
Conclusions: The severity of clinical manifestations of inflammation and disorders of the general condition depended on the activity of the course of chronic parenchimatic
parotitis and were more pronounced when active. During the remission period, no apparent clinical manifestations were detected in 72% of observations, however, in 28%, the
identified signs indicated a latent course, which required additional treatment and rehabilitation measures.
CLINICAL-MORPHOLOGICAL CHARACTERISTICS AND PECULIARITIES OF TREATMENT OF PARAURURICULAR FISTULAS IN CHILDREN
Authors: Tkachenko Pavlo I. , Starchenko Ivan I. , Bilokon Serhii O. , Popelo Yuliia V. , Lokhmatova Nataliia M. , Dolenko Olha B. , Korotych Nataliia M. , Hohol Andrii M. , Bilokon Nataliia P.
Published: October 2020

The aim: Determining the frequency of occurrence of paraauricular fistula in children and comparing the results of their own experience regarding their clinical manifestations,
treatment principles and morphological features with existing scientific data.
Materials and methods: The results of a comprehensive examination and surgical treatment of 25 children with paraauricular fistulas.
Results: Most often, para-auricular fistula was observed in infants 22 – (88%). In 18 persons (72%), they were unilateral, in 10 – (40%) hereditary. In 8 – (32%), fistula was
diagnosed immediately after birth. In 17 – (68%) the pathology was not clinically manifested, but was an accidental finding during the next medical examination. Morphological
research has shown that congenital paraauricular fistula is a formed canal intimately associated with the epithelium and cartilage, and the presence of epithelial lining on the
fistula wall with constant support of the inflammatory process makes it impossible to heal even against the background of multicomponent treatment.
Conclusions: Due to the topographic-anatomical localization, features of the clinic of the born fistula, surgical treatment does not always allow to achieve the desired results, and
requires repeated interventions during recurrence. It is possible to prevent recurrence by the extensive use of additional diagnostic manipulations before surgery and careful
wound control during surgical procedures.
FEATURES OF MECHANICAL INJURIES OF THE LOWER EXTREMITIES ACCORDING TO A FORENSIC MEDICAL EXAMINATION: A RETROSPECTIVE ANALYSIS
Authors: Sokol Viacheslav K. , Sokol Kostyantin M. , Kolesnichenko Vira A.
Published: October 2020

The aim: To study the structure of lower extremities’ mechanical injuries and the reasons for an additional (commission) forensic medical examination appointment, according
to a retrospective analysis.
Materials and methods: research protocols were116 reports of additional (commission) forensic medical examinations of victims with mechanical trauma to lower extremities;
research methods – retrospective analysis, statistical method. Reports of forensic medical commission examination were selected by random sampling, for the period February
– June 2018.
Results: As a result of a retrospective analysis of commission (additional) forensic medical examination, the prevalence of road traffic injuries (109; 94.0% cases) in mechanical
injuries of the lower extremities was established. Domestic (5; 4.2%), work (1; 0.9%) and sports (1; 0.9%) injuries were also indicated It was found that to establish the degree
of permanent disability loss according to the outcome of fractures of the femur and shin bones, commission examinations were appointed in 24.1% of cases. The main reason
for the commission examinations appointment was to establish the bodily injuries presence (6.9%), as well as to establish the bodily injuries presence and their severity (62.9%)
in cases of road traffic injury (lethal and non-lethal).
Conclusions: The use of commission forensic medical examination is mainly related to the criminal law criteria of the preliminary investigation stage. The reason for conducting
commission examinations on medical criteria is to establish the outcome of a fracture of the lower limb.
QUALITATIVE ANALYSIS OF ORAL LACTOBACILLI PARAMETERS AT DIFFERENT STAGES OF HUMAN LIFE CYCLE AND DIFFERENT CARIES INDICES
Authors: Zaytsev Andrii V. , Boychenko Olha N. , Sidash Yuliia V. , Kotelevska Natalya V. , Nikolyshyn Anatolii K.
Published: October 2020

The aim of this article is to provide the detailed study of the changes in the lactobacilli indices of the oral biotope in health and in caries progression in individuals.
Materials and methods: Materials included on reports and data of research projects conducted at the Department of Therapeutic Dentistry and Department of Microbiology,
Virology and Immunology, Ukrainian Medical Stomatological Academy (Poltava), at the Department of Microbiology of Danylo Halytsky National Medical University (Lviv),
completed in 2013;research data documented by the Department of Microbiology, Medical Stomatological Institute (now Ukrainian Medical Stomatological Academy, Poltava)
in 1978; literature related to the subject matter. Methodology: the standard methods of dental examination recommended by WHO; methods of system analysis and system
approach, bibliosemantic analysis .
Results: The presented results indicate that the number of representatives of different types of oral microflora in the oral microbiocenosis is different at different stages of human
life. The content of Lactobacilli in children decreases following the rise even under increased dmft indices.
Conclusions: The data observed are of great clinical interest when considering the role of Lactobacilli in the protection of the host organism and the initiation of the carious process.
DIFFERENTIAL DIAGNOSTICS OF INHERITED METABOLIC DISORDERS IN NEWBORNS
Authors: Znamenska Tetiana K. , Vorobiova Olga V. , Holota Тetiana V. , Kryvosheieva Vera V. , Pokhylko Valeriy I.
Published: October 2020

The aim: To compose an applicable diagnostic checklist for neonatologists, pediatricians, and general practitioners who refer newborns with certain inherited metabolic diseases
(IMDs) suspicion to confirmatory testing laboratories.
Materials and methods: Analyzed international and generally, known national clinical guides and recommendations devoted to IMDs diagnostics, treatment and follow up.
Results: Considering integral character of the diagnostic work-up of inborn errors of metabolism, authors of this article composed an applicable checklist that comprises set
of data necessary for interpretation the positive results of expanded newborn screening and making decision of appropriate biochemical and molecular tests are required for
confirmatory follow-up testing to establish the diagnosis and prescribe pathogenetic therapy.
Conclusions: Properly filled checklist allow metabolic professionals to select appropriate confirmatory tests and interpret results obtained. Early IMDs diagnosis and prompt
treatment initiation are crucial for positive outcomes and proved to be an effective tool to decrease levels of child disability and infant mortality.
STRENGTH COMPARISON OF DIFFERENT METHODS OF CLOSING THE ANTERIOR ABDOMINAL WALL DEFECT (EXPERIMENTAL STUDY)
Authors: Ioffe Oleksandr Yu. , Tarasiuk Tetiana V. , Kryvopustov Mykola S. , Stetsenko Oleksandr P. , Tsiura Yuri P. , Dibrova Yuri A. , Vasilyev Artem V.
Published: October 2020

The aim of the study is to compare the mesh implantation and the strength of the mesh fixation to the anterior abdominal wall by modelling the intraperitoneal onlay mesh
repair (IPOM) with and without aponeurotic defect closure.
Materials and methods: The experimental animals were randomly divided into 2 groups of 6 rabbits. In experimental group IPOM was modelled without hernia defect closure,
in control group – with its suturing. The macroscopic assessment of the severity of adhesions, histological examination of the removed “anterior abdominal wall – mesh” complex
and strength of the mesh fixation to the anterior abdominal wall were performed on the 90th day.
Results: In both groups, the displacement or complete separation of the mesh from the parietal peritoneum was not observed. The extent of adhesion formation in the abdominal
cavity and strength of the mesh fixation are comparable in both groups (p > 0.05). In the experimental group, the mesh was surrounded by scar tissue, mesothelioma lining
was not traced. There were also moderate signs of inflammation, which were not seen in the control group.
Conclusions: The strength of the mesh fixation to the parietal peritoneum and its implantation into the anterior abdominal wall is comparable with or without aponeurotic
defect closure during the experimental modelling of IPOM.
CLINICAL AND LABORATORY ASPECTS OF ACUTE OBSTRUCTIVE BRONCHITIS IN CHILDREN INFECTED WITH MYCOPLASMA PNEUMONIAE
Authors: Usenko Svitlana H. , Yeloeva Zalina V. , Diachenko Maryna S. , Usenko Serhiy A.
Published: October 2020

The aim of the work is to improve the prognosis of acute bronchitis on the basis of the study of etiology, clinical anamnestic and laboratory-instrumental features of acute
bronchitis in children infected with Mycoplasma pneumoniae.
Materials and methods: Medical records of inpatients, data from laboratory and clinical examinations, orders from the Ministry of Health of Ukraine. Statistical processing of
the obtained results was carried out with the calculation of parametric and non-parametric criteria. The study included 72 patients with acute obstructive bronchitis, infected
with Mycoplasma pneumoniae and patients not infected with intracellular pathogens who were hospitalized under the conditions of pediatric ward of children of younger and
older children of the National Children’s Clinical Hospital №24.
Results: Found that infected with mycoplasma compared with uninfected intracellular infection, more characteristic course of acute obstructive bronchitis on the background
of febrile temperature with its duration of more than 4 days, the presence of midbubble and single dry or wet rales, as well as. In general, in patients infected with mycoplasma,
compared with patients infected with chlamydia, there is a higher functional stress of immunity with the phenomena of exhaustion.
Conclusions: Attention is drawn to the fact that clinical, laboratory data and immunological examinations with the use of systematic analysis make it possible to predict the
consequences in the history of children with intracellular infections of various somatic pathologies. In doing so, multivariate and correlation analyzes make it possible to develop
new diagnostic criteria.