bluuebunny/crossref_metadata_2025 huggingface dataset:
The efficacy of technology designed to support older adults’ chronic disease self-management: A systematic review. (Preprint)
Authors: Murdock Paul , Senteio Charles
Published: May 2024

BACKGROUND

Amid the proliferation of health information technology (HIT) designed to support patients in following recommended chronic disease self-management behaviors (i.e., medication behavior, physical activity, dietary behavior and attending follow-up appointments), health inequities persist among older adults for chronic disease outcomes. Numerous interventions that use consumer-oriented HIT to support self-management have been evaluated, and some of the related literature has focused on older adults who experience disparate chronic disease outcomes. However, little is known about the efficacy of these interventions.

OBJECTIVE

This study aims to conduct a systematic review of the literature that describes the efficacy of consumer-oriented HIT interventions designed to support self-management involving older adults.

METHODS

We followed an a priori protocol using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses)-Equity 2020 Extension guidelines for systematic reviews that focus on health equity. Themes of interest included the inclusion and exclusion criteria. We identified seven electronic databases, created search strings, and conducted the searches. We initially screened results based on titles and abstracts and then performed full-text screening. We then resolved conflicts and extracted relevant data from the included articles.

RESULTS

In total, there were seven included articles. All studies included older adult patients, which we define as 65 or older. All studies focused on technologies that support chronic disease self-management for older adults, such as medication behavior, and dietary behavior, and physical activity, and attending follow-up appointments. Medical specialties ranged from physical rehabilitation, to computer engineering, to internet research, etc. Study types included non-experimental (5/7, 71%), non-randomized clinical trial (1/7, 11%), and single-blind randomized controlled trial (1/7, 11%).

CONCLUSIONS

This study addresses a key gap in research that has not sufficiently examined what technology designs and capabilities may be effective in supporting older adults following recommendations for chronic disease self-management.
Study on The Design Scheme of The East Extension Project of Qiushi Elevated Road
Authors: Qi Gaoyuan , Lin Jingquan
Published: May 2024

This paper takes the east extension project of Qiushi elevated road as an example, according to the planning and status quo situation of the project, combined with the traffic forecast and the analysis of the status quo, through the comprehensive selection of the program, the most reasonable scheme is selected from the aspects of scheme feasibility, traffic function and economy.
Cartas a las madres
Authors: Mayer Mónica , Casas Herrera Andrea , Gargallo Celentani Francesca , Huerta Tamayo Gabriela , Hernández Iliana , Robles Ambrosio Margarita , Stengel Peña Natalia , Hernández Reyes Vanessa , González Aquino Jennifer
Published: May 2024

El concurso "Cartas a las madres" se realiza con el fin de homenajear a las colectivas de madres de desaparecidas y de asesinadas por feminicidio que buscan justicia en México, quienes llevan a cabo una tarea fundamental en la lucha por el respeto a los derechos humanos.
Diálogos poéticos: Creadoras y académicas
Authors: Galván Kyra , Lorenzano Sandra , Machado Vento Dainerys , Moscona Myriam , Muñiz-Huberman Angelina , Nozal Carmen , Salvia Claudia , Santibáñez Julia , Swanson Rosario , Trejo Sirvent Marisa , Vieitez Sabater Paulina
Published: May 2024

Estos diálogos abren con la participación de Gela Manzano, precisamente con su respuesta a Teresa Wilms Montt, a la que se agrega un análisis sobre su obra Anuarí, que realizó con la asistencia de una de sus estudiantes; ambas perspectivas recorren el espíritu de este proyecto: reunir la creación poética y el ensayo académico, y dan paso a las autoras que se nos fueron sumando, aquí, por orden alfabético, presentando, cada una, su manera de leer, entender, responder y compartir a la autora de su elección.
GAN-Based Super Resolution Algorithm for High-Quality Image Enhancement
Authors: Singh Anjali
Published: May 2024

Abstract: Super Resolution: Leveraging investigates the trans-formative potential of Generative Adversarial Networks (GANs) in the context of super resolution, utilizing state-of-the-art algorithms to achieve high-quality image enhancement. The study encompasses a comprehensive analysis of GAN architectures suchas SRGAN, ESRGAN, and others, exploring their strengths, limitations, and practical applications. The proposed methodology delves into dataset selection, preprocessing techniques, and the integration of advanced algorithms within the GAN framework. It evaluates the quantitative and perceptual performance of these techniques, addressing challenges and proposing avenues for future research. The findings contribute to the evolving landscapeof GAN-based super resolution, offering insights for researchers and practitioners in advancing image enhancement technologies
Underground Cable Fault Detection Using IOT
Authors: J Prof. Mrs. Gayathri , R Shashank , M Sai Vamshi , K Hareesha , Sohail Mohammed
Published: May 2024

Abstract: The objective of this project is to determine the distance of underground cable fault from base station in kilo meters using an Arduino. The underground cable system is a common practice followed in many urban areas. An issue may happen in an underground cable just because of earth tremors or any burrowing procedure. Since the area of the issue happened is obscure it is very hard for the fixing procedure. This hindrance is handled with the assistance of optical fibre framework. A lot of optical strands is put alongside the force cables. While a fault occurs for some reason, at that time the repairing process related to that particular cable is difficult due to not knowing the exact location of the cable fault. The proposed system is to find the exact location of the fault. The project uses the standard concept of Ohms law i.e., when a low DC voltage is applied at the feeder end through a series resistor (Cable lines), then current would vary depending upon the location of fault in the cable. In case there is a short circuit (Line to Ground), the voltage across series resistors changes accordingly, which is then fed to inbuilt ADC of Arduino to develop precise digital data for display in kilometres. The project is assembled with a set of resistors representing the cable length in km and the fault creation is made by a set of switches at every known km to cross check the accuracy of the same. The fault occurring at a particular distance, the respective phase along with the distance is displayed on the LCD. The same information is also sent over IOT, interfaced to the Arduino. Further this project can be enhanced by using capacitor in an ac circuit to measure the impedance which can even locate the open circuited cable, unlike the short circuited fault only using resistors in DC circuit as followed in the above proposed project.
IOT - Enabled Digital Vehicle Parking Systems using Machine Learning
Authors: Sanghvi Ankush
Published: May 2024

Abstract: In large cities, parking availability is a major problem. Car owners are confused by crowded reserved parking spaces during rush hour. To overcome this obstacle, modernizing the parking system is crucial. This research will conduct an in-depth and thorough literature review of past studies and project implementations to identify best practices and gaps in the existing research. The goal is to analyze previous work comprehensively, highlighting successful approaches and areas where further investigation is needed.In this study aims to perform a detailed and comprehensive examinations of previous research and research executions to precise effective strategies and deficiencies in the current body of research.The objective is to thoroughly evaluate prior efforts,emphasizing successful methodologies and areas requiring additional investigation.A prototype of the digital vehicle Parking System is implemented via an Android application leveraging Firebase and IoT based on AI . This makes it easy for drivers to find parking spaces with assigned spaces.
Design and Construction of 3 DOF Prototype Delta Parallel Robot
Authors: Myklebusthaug Theodor
Published: May 2024

Abstract: The design and construction of a prototype delta robot to utilize for upper secondary educational institutes is presented. The focus is on leveraging 3D printing technology in AutoCAD for component fabrication, detailing electrical schematics, and integrating Arduino for its intuitive User Interface (UI). The project’s objective is to construct a delta robot prototype equipped with essential features to serve as an educational tool for teaching fundamental robotics principles. Additionally, the design allows for customization of specific robot parts in future iterations to adapt it to various applications as needed
Towards Secure and Transparent Elections: A Review of Electronic Voting Integrated with Blockchain Technology
Authors: Ingole Avinash
Published: May 2024

Abstract: This paper provides an in-depth examination of the integration of blockchain technology with electronic voting (evoting) systems, aimed at ensuring the security and transparency of electoral processes. While prior research predominantly focused on the technical aspects of e-voting, recent efforts have acknowledged the intricate socio-technical dynamics at play. Drawing on conceptualizations and principles that view e-voting as complex socio-technical frameworks, this paper explores avenues for enhancing accessibility, efficiency, and integrity. Blockchain technology emerges as a transformative solution, offering cryptographic assurances to address vulnerabilities like data manipulation and centralization. Through blockchain integration, e-voting systems can uphold crucial principles such as verifiability, anonymity, fairness, and transparency, thus fostering trust in electoral procedures. The proposed systems leverage cryptographic techniques and smart contracts to protect voter anonymity, ensure data integrity, and enable end-to-end verification. Furthermore, the paper advocates for decentralized architectures to mitigate risks associated with centralized databases. By emphasizing the pivotal role of blockchain technology, this paper contributes to the advancement of e-voting systems towards secure and transparent elections.
Implementation of Smart 24x7 Women Security App W-SAFE
Authors: Vats Nandini
Published: May 2024

Abstract: Physical assaults and other forms of violence against women have increased in recent years. The increasing number of women working in industries and other commercial sectors has made it necessary for them to travel at odd hours and visit remote and isolating places as part of their jobs. Defence is not the sole tactic that can be sufficient to stop this growing misuse. It is necessary to come up with a security strategy that gives women a means of safety. As a result, a more straightforward safety solution is required, one that may be triggered by merely pressing a button and that can immediately notify the victim's loved ones. Therefore, the project's main focus is on a safety system that is made for women so that they never feel helpless while facing a security threat it is specifically designed to give women protection and safetyso they never feel powerless in the face of such social issues. A machine learning algorithm is used to enhance the responsiveness of an android application that records women's live whereabouts and includes voice activation, crowd space rating, emergency hotline numbers, and safe route suggestions. Giving users access to current information about locations where other people have expressed safety concerns is the goal. The program wouldautomatically sound a warning when approaching such regions in order to increase user awareness and encouragea proactive approach to personal safety
Impact of Aerobic Conditioning on Endurance and Agility in Ball Badminton Players of Mumbai
Authors: Sonwane Umesh
Published: May 2024

Abstract: This study explores the effects of systematic aerobic conditioning on the endurance and agility of ball badminton players in the Mumbai region. Utilizing a controlled experimental design, 60 male and female players, aged 18-25, were divided into two groups: an experimental group receiving aerobic conditioning three times a week, and a control group following traditional training routines. The aerobic regimen included activities such as running, high-intensity interval training (HIIT), and circuit training, each tailored to enhance cardiovascular fitness and muscular endurance. Pre- and post-intervention assessments over a 12-week period involved the Cooper 12-minute run test for endurance, and the Illinois Agility Test for agility. Results indicated significant improvements in the experimental group compared to the control group. Specifically, the experimental group showed an average increase of 15% in the distance covered during the Cooper test, and a decrease in completion time by an average of 4.2 seconds in the Illinois Agility Test. These findings suggest that aerobic conditioning notably enhances both the endurance and agility of ball badminton players. The improvement in physical capacities likely contributes to better in-game performance, suggesting that integrating aerobic conditioning into regular training schedules could be beneficial for competitive ball badminton players in regions similar to Mumbai.
Spiritual Understanding of Muladhara Chakra – A Review Study
Authors: Kumar Sunil
Published: May 2024

Abstract: The earliest references to Shatchakra concepts in India begin with the early indications of the subtle body and can be found in the Upanishads' Tantra and Yoga writings. A good explanation is necessary to uncover the concept of several regulatory Chakras in the human body. Chakras are pools of energy throughout the body that circulate energy into the vital system and govern consciousness and many physiological and psychological processes within the human body. The purpose of this study is to investigate Muladhara Chakra and the meaning behind Chakras in order to improve comprehension and provide greater insight into the ideas. Chakras are not physical entities, and we cannot perceive this fine channel with our eyes. As The thorough knowledge of Muladhara Chakra, along with its structural correlation, is very essential for yogic understanding and its significance in our body. The paper reviewed the Muladhara Chakra on the basis of Vedic or ancient literature.
Quality Assessment of Developed Cumin Cookies
Authors: Meshram Ankit Ashok , Rajgade Namrata Manoj , Rajgade Natasha Manoj , Niruba Pricy , Watkar Prashant
Published: May 2024

Abstract: Cookies are good carrier of nutrients like carbohydrate and fat which can be enriched with protein. Refined Flour is the finest type of wheat flour containing high calorie content but minimal nutritional value that is used to make pizza, bread, samosa, kachoris, puri, cakes and biscuits.by partially replacing refined wheat flour with wheat flour up to an acceptable level. It is a fast and quick recipe for cookies made with Refined wheat flour, wheat flour and cumin seeds. The special characteristic of these cookies is that, as opposed to other cookie recipes, they do not contain plain flour, sugar or even jaggery. It is an excellent snack or coffee snack for munching and is enjoyed by all age groups, including children and adults because of its rich nutrients.
Sustainability consciousness in higher education: Construction of three-dimensional sustainability and role of locus of control
Authors: Farliana Nina , Hardianto Hanif , Rusdarti Rusdarti , Sakitri Wijang
Published: May 2024

This study aims to analyze the level of sustainability awareness among university students, especially focusing on their knowledge, attitudes, and behavior related to sustainability across three main dimensions: environmental, social, and economic. Additionally, the study explores whether these behaviors are influenced by individuals’ beliefs about their ability to effect change. This study employed a quantitative approach involving all active students enrolled in the Faculty of Economics and Business, Universitas Negeri Semarang. A samples of 233 respondents was selected using a non-probability sampling method. Data was collected through a questionnaire and analyzed using the Structural Equation Modeling Partial Least Square method. The study findings reveal that attitude towards sustainability have stronger influence on behavior than knowledge. Respondents' demonstrated a higher level of understanding of sustainability compared to their attitudes and behaviors towards it. Furthermore, concerns to economic aspects were found to impact sustainability behaviors. Most respondents expressed a belief that events around them are beyond their control. This article is expected to significantly contribute to aligning policies and practices, particularly in fostering sustainability awareness, and serve as a basis for achieving sustainable development initiatives.
Patient Voice Program and Citizen Voice and Action: Leaders’ responsiveness to RMNCH gaps raised by citizens through community scorecard meetings in Rwanda: A cross-sectional study
Authors: Mazimpaka Christian , Ndatimana Dieudonne , Murerwa Betty , Hirwa Celine , Ndibaza Amedee Fidele , Mutuyimana Christelle , Kulaaza Benjamin
Published: May 2024

Background: The Patient Voice Program and Citizen Voice and
Action models use scorecard meetings for community-provider-government
dialogue to improve health services. This study evaluates the
responsiveness of leaders and providers to concerns voiced by citizens
through these scorecard meetings at the health center and district
office levels in Rwanda. Methods: We conducted a
cross-sectional study from July to September 2022 in 325 Rwandan health
centers across 20 districts. Responsiveness was measured by comparing
resolved issues to raised issues. Logistic regression identified
predictors of issue resolution, with a p-value less than 0.05 considered
significant. Median responsiveness turnaround time was also analyzed.
Results: In total, 59.4% (1,163) of the identified gaps were
resolved. Facility-level issues experienced a higher resolution rate
(65.9%) than district-level issues (35.4%). Gaps at the facility level
were 3.24 times more likely to be resolved than those at the district
level (OR: 3.24, p<0.001, 95% CI: [2.48,4.25]).
Integrated gaps had 1.46 times higher odds of resolution compared to
issues stemming from reproductive, maternal, newborn, and child health
services (OR: 1.46, p<0.05, 95% CI: [1.13,1.88]). The
median responsiveness turnaround time for resolving a gap was
approximately 15.4 months (IQR: 6.7-25.8). Conclusions: The
study shows that Patient Voice Program and Citizen Voice and Action
models are effective in addressing healthcare service gaps. By promoting
collaboration among communities, healthcare providers, and governments,
these models facilitate targeted, locally-supported solutions that
significantly improve the resolution of health service delivery issues.
The uptake and associated factors of Tuberculosis preventive therapy among people living with HIV in Kasungu district, Malawi: a cross-sectional study
Authors: Chirwa Samuel , Sambani Clara , Mphoka Bwanali , Nkhoma Frazer , Sinyiza Frank , Mwale Saul , Mwenyemkulu Tisungane , Mpunga James , Mbendera Kuzani , Kanyerere Henry , Lwanda Levi , Chimatiro Dickens , Golombe Emmanuel , Mbakaya Balwani , Chisale Master
Published: May 2024

Introduction Tuberculosis (TB) is the leading cause of death
from a single infectious agent. Risk of TB disease is higher among
people living with HIV. HIV prevalence among tuberculosis patients is in
Africa is approximately 38%. Malawi registered a 44.6% TB/HIV
coinfection in 2020. TPT prevents development of active TB disease. TPT
uptake has been suboptimal Malawi. We conducted a study assessing the
uptake of TPT and associated factors among PLWHIV in Kasungu district,
Malawi. Methods A quantitative cross-sectional study among
PLHIV from the 2021 cohort in Kasungu district. Target participants were
from health facilities that provide TPT. An adapted questionnaire was
used to collect socio-demographic factors including age, sex, education,
residence, religion, marital status, economic status and assessed the
knowledge of participants about TPT with their understanding of the use
of TPT. The data was subjected to descriptive, bivariate and logistic
regression analyses in SPSS version 25. Results Uptake of TPT
was at 62%. Seventy five percent of the participants had good knowledge
about TPT. Low uptake of TPT was associated with low education status,
poor knowledge about TPT, being on ART for more than 24 months and
receiving services at rural hospitals. Conclusion Low uptake of
TPT needs to be addressed. There is for intensified health communication
and promotion about TPT among the PLWHIV including diversifying the
communication messages and channels to reach all literacy levels.
Further studies are needed to ascertain other factors including the
health care workers’ attitudes and perception about TPT.
A Meta-analysis of asthma and wheeze prevalence among preschool and school-aged children in Africa.
Authors: Rodney R Mudau , Joyce J Shirinde , Kuku K Voyi
Published: May 2024

Background: Asthma and wheezing are significant health concerns
for children in Africa. There is a dearth of prior research examining
the occurrence of asthma and wheezing in both preschool and school-aged
children within the African environment. Therefore, this meta-analysis
aimed to estimate the prevalence of asthma and wheezing in African
infants from zero months to children eight years of age.
Methods: An electronic search was conducted in July 2023 in
Scopus, Web of Science, PubMed, MEDLINE, CINAHL, and Academic Search
Complete for studies published from January 2012 to July 2023 using the
following subject-specific terms: 1. “Risk factors” OR “Contributing
factors” OR “Predisposing factors” OR “Predictor” OR “Cause” OR
“Prevalence” OR “Trends” 2. “Asthma” OR “Wheeze” OR “Wheezing”
OR “Asthma symptoms”, 3. “Preschool” OR “early childhood” OR
“kindergarten” OR “0 to 8 years” OR “School children”, 4. Africa/
or, 5. limit to (English language and year=“2012 -Current” and
children). STATA 17 software and a fixed effects model were utilized.
Heterogeneity was assessed using I2. Results: The study
revealed a prevalence of asthma in preschool and school-aged children of
4.41%, with no heterogeneity observed ( I2 <0).
Wheezing in the past prevalence rate was 22.91%, also without
heterogeneity ( I2 <0), with no significant differences
observed among the studies. This indicates a lack of heterogeneity in
studies for asthma and wheezing prevalence rates. Conclusions:
Asthma and wheezing are prevalent among African preschool and
school-aged children, highlighting the need for comprehensive and
localized research to address this public health issue.
Transport and distribution of sodium ions in Mercury’s magnetosphere: results from multi-fluid MHD simulations
Authors: Chen Yuxi , Dong Chuanfei , Sun Weijie
Published: May 2024

In the absence of a substantial ionosphere, solar wind protons dominate
the plasma content within Mercury’s magnetosphere. However, Mercury is
surrounded by a tenuous neutral exosphere composed primarily of sodium
atoms, which can be continuously ionized. The production of sodium ions
is concentrated on the dayside, and these ions can subsequently be
transported to the magnetotail and flanks. MESSENGER spacecraft
observations revealed dawn-dusk asymmetric distributions of sodium ions
$Na^+$. In this study, we present a two-fluid MHD model that is
coupled with an empirical sodium exosphere profile to investigate the
circulation, distribution, and influence of $Na^+$ on global
magnetospheric convection. Our findings indicate that the observed
dawn-dusk asymmetries in $Na^+$ distributions are driven by the
separation of $H^+$ and $Na^+$ flows, with the Hall-driven
global convection preferentially transporting $Na^+$ ions to the
morning sector.
Impacts of Forest Management-Induced Productivity Changes on Future Land Use and Land Cover Change
Authors: Luo Meng , Daigneault Adam , Zhao Xin , Hao Dalei , Chen Min
Published: May 2024

Anthropogenic land use and land cover change (LULCC), is projected to
continue in the future. However, the influence of forest management on
forest productivity change and subsequent LULCC projections remain
under-investigated. This study explored the impacts of forest
management-induced change in forest productivity on LULCC throughout the
21st century. Specifically, we developed a framework to softly couple
the Global Change Analysis Model and Global Timber Model to consider
forest management-induced forest productivity change, and projected
future LULCC across the five Shared Socioeconomic Pathways (SSPs). We
found future increases in forest management intensity overall drive the
increase of forest productivity. The forest management-induced forest
productivity change shows diverse responses across all SSPs, with a
global increase from 2015 to 2100 ranging from 3.9% (SSP3) to 8.8%
(SSP1). This further leads to an overall decrease in the total area with
change of land use types, with the largest decrease under SSP1 (-7.5%)
and smallest decrease under SSP3 (-0.7%) in 2100. Among land use types,
considering forest management-induced change significantly reduces the
expansion of managed forest, and also reduces the loss in natural land
in 2100 across SSPs. This suggests that ignoring forest
management-induced forest productivity change underestimates the
efficiency of wood production, overestimates the managed forest
expansion required to meet the future demand, and consequently,
potentially introduces uncertainties into relevant analyses, e.g.,
carbon cycle and biodiversity. Thus, we advocate to better account for
the impacts of forest management in future LULCC projections.
Sensing a Connection: Tree Distribution is Influenced by Deep Critical Zone Structure
Authors: Flinchum Brady A , Harman Ciaran J , Hagan Donald
Published: May 2024

This study explores the impact of deep ( >5 m) critical
zone (CZ) architecture on vegetation distribution in a semi-arid
snow-dominated climate. Utilizing seismic refraction surveys, we
identified a significant correlation between saprolite thickness and
LiDAR-derived canopy heights (R²=0.47). We argue that CZ structure,
specifically shallow fractured bedrock under valley bottoms, redirects
groundwater to locations where trees are established—suggesting they
are located in specific locations with access to nutrients and water.
This work provides a unique spatially exhaustive perspective and adds to
growing evidence that in addition to other factors such as slope,
aspect, and climate, deep CZ structure plays a vital role in ecosystem
development and resilience.
Emphysematous pyelonehpritis a vese akut gyulladásának különleges esete = Emphysematous pyelonephritis, a special case of inflammation of the kidney
Authors: Altenni Mohammed , Zóber Tamás , Csapó Judit , Beliczay Barbara , Vrecenár László , Buzogány István
Published: May 2024

Bevezetés: Az emphysematous pyelonephritis (EPN) ritka, súlyos és magas mortalitású akut fertőző vesebetegség. Magas halálozási aránya miatt intenzív terápiát és széles spektrumú antibiotikumkezelést igényel. A kardiorespiratórikus funkciók stabilizálását követően korai intervenciós vagy sebészi megoldása javasolt. A háttérben kimutatható kórokozók az Escherichia coli, a Proteus mirabilis, Klebsiella pneumoniae D-csoportú Streptococcus és koaguláz negatív Staphylococcus, ritkán gomba (Candida albicans). Beteganyag és módszer: Osztályunkon 2017. októbertől 2020. januárig 5 beteget kezeltünk emphysematous pyelonephritis miatt. A betegek többségénél kezeletlen hyperglykaemia is felismerésre került. Valamennyi esetben trifázisos CT-vizsgálattal diagnosztizáltuk az elváltozást. A kórkép felismerését követően azonnali, széles spektrumú antibiotikumterápia és dupla-J katéter vagy transrenalis drén behelyezése, szükség esetén feltárásos műtéti beavatkozás történt. Két betegnél egyoldali nephrectomiát, egy krónikus veseelégtelenség miatt hemodializált betegnél kétoldali nephrectomiát végeztünk. Eseteink között halálos kimenetel nem fordult elő. Eredmények: Egy 53 éves férfi beteg esetének bemutatásával szeretnénk felhívni a figyelmet az emphysematous pyelonephritis kórképére. A kialakult kórkép kivizsgálása kapcsán derült fény kezeletlen cukorbetegségére, ennek rendezését követően, széles spektrumú antibiotikumkezelés és bal oldali veseüregrendszeri tágulata miatt dupla-J katéterfelhelyezés történt. A beavatkozások együttes hatására a beteg állapota rendeződött, gyógyultan távozott otthonába. Megbeszélés: Az EPN rendkívül figyelemre méltó és az eddig gondoltnál jóval többször megjelenő kórkép, a mai napig halálos veszedelmet jelent a betegek számára, amennyiben nem multidiszciplinárisan és nem megfelelő módon történt a kezelésük.
MR-fúziós ultrahangvezérelt prosztatabiopszia a Péterfy Kórházban
Authors: Ráfi Tamás , Volford Gábor , Zóber Tamás , Beöthe Tamás , Buzogány István , Markó Róbert , Kardos Lilla , Papp Éva , Dombóvári Péter
Published: May 2024

Bevezetés: A prosztatarák a második leggyakoribb rosszindulatú daganatos elváltozás a férfiak körében. Diagnosztikájában az MR-vizsgálat fejlődése nagy áttörést hozott, újfajta célzott mintavételi technikák lehetőségét teremtette meg. Célkitűzés: Vizsgálatunk célja az volt, hogy összegezzük kezdeti tapasztalatainkat az általunk végzett mpMR fúziós prosztatabiopsziák terén. Továbbá a kapott eredmények tanulsága alapján növeljük a jövőbeni mintavételek sikerrátáját. Anyag és módszerek: A Péterfy Kórház-Rendelőintézet és Manninger Jenő Országos Traumatológiai Intézet Urológiai Osztályán 2020. február és 2021 márciusa között összesen 36 páciens esetében végeztünk transrectalis ultrahangvezérelt mpMR fúziós prosztatabiopsziát, az ultrahangkészülékhez biztosított V-nav navigációs program segítségével. Az MR-vizsgálatok értékelése a PI-RADS v2 ajánlása szerint történt. Elemeztük, hogy az MR-en észlelt léziók PI-RADS besorolása, mérete, elhelyezkedése, extraprosztatikus terjedés jeleinek megléte, illetve a betegek szérum PSA-szintje, PSAD-értéke, továbbá prosztatatérfogata miként befolyásolta a biopsziák eredményét. Eredmények: A biopsziák szövettani feldolgozása alapján a páciensek 64%-ában igazolódott prosztatadaganat. Az MR által leírt elváltozásokból célzottan vett minták hisztológiai eredményeit elemezve, a PI-RADS 5-ös besorolású gócok esetén a találati arány 57% volt, míg a PI-RADS 4-es léziók esetén 26%. A tranzicionális zónából kiinduló elváltozások esetén nagyobb arányban igazolódott malignitás a hisztológiai vizsgálatok során, mint a perifériás zóna gócai esetén (56% vs. 33%). Az elváltozások nagyobb axiális átmérője (talált/nem talált 20,5 mm vs. 14 mm), a magasabb PSAD-értékek (talált/nem talált 0,22 ng/ml2 vs. 0,10 ng/ml2 ), és az extraprosztatikus terjedés jeleinek megléte mind növelték a mintavételek találati arányát. Az átlagos prosztatavolumen nagyobb volt azon páciensek esetében, akiknél a biopsziák nem igazoltak malignitást (71 ml vs. 58 ml). Következtetések: Az általunk végzett mpMR fúziós biopsziák eredményessége megfelel a nemzetközi adatoknak, ugyanakkor más hazai munkacsoport által végzett beavatkozások eredményeitől elmarad. Tapasztalataink alapján a mintavételek sikerességét befolyásolja az elváltozások PI-RADS besorolása, mérete, elhelyezkedése, extraprosztatikus terjedés jele, PSAD-érték, valamint a prosztata térfogata. Mindezen tényezőket érdemes figyelembe venni az indikáció felállításakor, hogy megfelelően kiválaszthassuk azon pácienseket, akik a legtöbbet nyerhetnek a beavatkozással.
A prosztatarák korszerű ellátásának feltételrendszere a betegek jó életminőségben eltöltött, hosszabb túléléséért
Authors: Tenke Péter , Bodoky György , Géczi Lajos , Mangel László , Maráz Anikó , Nyirády Péter , Polgár Csaba , Rózsa Péter , Csizmadia Ádám
Published: May 2024

Cél: A prosztatadaganatok ellátása komplex társadalmi feladat: az orvosszakmai kihívásokon túl jelentősek a betegség egyéni és össztársadalmi terhei is. Ezért tanulmányunk célja, hogy olyan ajánlásokat fogalmazzon meg az érintett szakmai szervezetek és a döntéshozók számára, amelyekkel tovább javítható a prosztatarákkal élő férfiak életkilátása és életminősége. Módszertan: Elemzésünk módszertanilag négy forráson alapszik, amelynek része a problémakörrel foglalkozó szakirodalmak feltárása, a hazai publikus adatbázisokban elérhető releváns adatok bemutatása, számos szakértői mélyinterjú, valamint az előzetes eredmények megvitatása kerekasztal-megbeszéléseken. Eredmény: Tanulmányunk fő megállapítása, hogy egyes részterületeken jelentős fejlődés történt az elmúlt években, ugyanakkor a minden beteg számára elérhető, modern, standard, minőségi betegellátás érdekében további lépések megtétele szükséges. Következtetés: A kidolgozott javaslatok alapján, összhangban a hazai és nemzetközi szakmai iránymutatásokkal, valamint a European Association of Urology Whitepaper on Prostate Cancer tanulmányával, véleményünk szerint kijelölhetőek azok a beavatkozási pontok, amelyek hozzájárulhatnak a standard és magas minőségű betegellátáshoz és ezáltal a betegek jó életminőségben eltöltött, hosszú túléléséhez.
Nem izominvazív hólyagdaganatok fizikai tulajdonságainak és a WHO 1973 és 20004/2016 grading rendszereinek szerepe a daganatok kiújulásának előrejelzésében
Authors: Erdélyi Balázs , Mansour Bassel , Kovács István , Kovács Péter , Monyók Ádám , Vadnay István , Lovasné Avató Judit , Tóth Erika
Published: May 2024

Bevezetés: Az urothelialis karcinóma az egyik leggyakrabban előforduló urológiai daganat világszerte. Tanulmányunk célkitűzése volt megvizsgálni, hogy a tumorok fizikai tulajdonságai, illetve a WHO grading rendszerek mennyire megbízhatóan jelzik előre a daganatok kiújulását. Betegek és módszerek: Vizsgálatunkban, Heves megyében a Markhot Ferenc Oktatókórház ellátási területén (jelenleg kb. 261 000 fő) 2009 és 2013 közötti időszakban kivizsgált és operált 305 hólyagtumoros esetet elemeztünk. Az elsődleges szövettani eredményeket a WHO 1973-as besorolás szerint dolgoztuk föl, ezt követően a szövettani blokkokat az Országos Onkológiai Intézet Patológiai Osztályán vizsgálták újra a WHO 2004/2016 besorolása szerint. Eredmények: A vizsgált 305 betegből az elsődleges feldolgozás szerint az igazolt malignus esetek száma 281 (92,13%), ezen belül 61,92% volt nem izominvazív hólyagtumor. A WHO 1973-as klasszifikáció alapján a nem izominvazív tumorok közül a betegek 63,8%-a volt T1G1, 24,72%-uk T1G2. Az újra feldolgozott, WHO 2004/2016 klasszifikáció alapján az értékelhető 277 minta 98,55%-a (273 minta) volt urothelialis karcinóma, ezek 74,36%-a (203 minta) volt nem izominvazív, 25,64% (70 minta) pedig izominvazív. Az újrafeldolgozott esetek 84%-ában megegyezett a szövettani stádium, 13%-ában alacsonyabb stádium, 3%-ában pedig magasabb stádium került megállapításra. Azokat az eseteket vizsgálva, amelyek mindkét klasszifikáció szerint nem izominvazív tumort véleményeztek, összehasonlításuk során a következő eredmények születtek: a T1G1-minta közül 63,64%-a TaLG (Ta low grade), 17,18%-uk TaHG (Ta high grade), 19,2%-uk pedig T1HG. A T1G2-minták közül 15,79%-a TaLG, 18,43%-a TaHG, 65,79%-uk T1HG.
Nem izominvazív hólyagtumoros betegek analízise klinikopatológiai szempontól Heves megyében
Authors: Monyók Ádám , Sereg Róbert , Vass István , Vadnay István , Kis Zsuzsanna , Lovasné Avató Judit , Mansour Bassel
Published: May 2024

Célkitűzés: A szerzők retrosprektív tanulmányának célja a nem izominvazív (NMIBC) hólyagdaganatok sajátosságainak felmérése ellátási területükön belül. Eredményeikkel javítani szeretnék a húgyhólyagtumorok diagnosztikáját, valamint pácienseik morbiditását illetve mortalitását. Betegek és módszer: Magyarországon Heves megyében 2009 és 2013 között, 305 húgyhólyagtumoros beteget operáltak (transurethralis húgyhólyagtumor-reszekció – Tu-TUR). A vizsgálati anyagukban az 1973-as WHO-besorolás szerint az NMIBC-betegek aránya 64,05%. Átlagosan 2-szer nagyobb az NMIBC előfordulási aránya a férfiaknál, mint a nőknél. Eredmények: A nem izominvazívként igazolt tumorok cisztoszkópos fizikai megjelenésének jellemzőit elemezve az esetek 20%-ában 3 cm-nél nagyobb tumort találtak. A tumorok 30%-a multiplex megjelenést mutatott a felfedezéskor. A nem izominvazív tumorok közül a 180 vizsgált beteg 20%-ánál volt recidíva. Ezek megoszlása 58,33%-a pT1-G1, 30,55%-a pT1-G2, 8,33% pTa-G1, 2,79%-a pedig pTa-G2 volt. Minél magasabb volt a korcsoport, annál rosszabb lett a vizeletcitológiai lelet (p=0,036) és a grade (p=0,023). Gyenge összefüggést találtak a tumor mérete, helye, valamint a grade között (p=0,26). Nagyobb méret esetén magasabb grade-et állapítottak meg. Statisztikailag szintén magasabb T-értéket találtak nagyobb méret esetén (p=0,2), valamint nagyobb méret esetén hamarabb újult ki a tumor (p=0,26). Megbeszélés: A szerzők adataik elemzésével szeretnének képet adni a magyarországi, azon belül is a Heves megyei húgyhólyagtumoros betegpopuláció sajátosságairól, ezek alapján javítani a korai és pontos diagnosztikát.
A prosztatakarcinóma kuratív kezelésének kihívásai a COVID-19-járvány idején
Authors: Darabos Norbert , Szepesváry Zsolt , Kullmann Tamás
Published: May 2024

Célkitűzés: A COVID-19 okozta pandémia Magyarországon is jelentős mértékben megváltoztatta békeidőben, a prosztatarák kivizsgálása és kezelése során alkalmazott algoritmusokat. Azt feltételeztük, hogy ez a változás rontotta a betegek prosztatarák specifikus gyógyulási esélyét. Anyag és módszer: Vizsgálatunkban a járvány alatt végzett laparoszkópos radikális prostatectomiák adatait hasonlítottuk össze a békeidőben végzett beavatkozásokéval. 2019. október és 2020. január között operált 19 beteg adatait elemeztük, akiknél az egészségügyi rendszer a szokott módon működött. A diagnózistól a műtétig eltelt idő átlagosan 3 hónap volt. Kontrollként 2020. október és 2021. január között operált 16 beteg adatait dolgoztuk fel. Ezen páciensek hozzáférése a járóbeteg-ellátáshoz csökkent, a diagnózistól a műtétig eltelt idő 4 hónap volt. A pácienseknél rögzítettük a biopszia eredményét, a Briganti-nomogram alapján számított kockázati értéket, a végleges szövettani lelet adatait és a posztoperatív PSA-értékeket. Ha a beteg kapott ADT-t a műtét előtt bármilyen okból, azt is feljegyeztük. Posztoperatívan 6 hónapig követtük mindkét csoportban a PSA-értéket, a korai biokémiai relapszust vizsgáltuk. A műtétet követően 3 és 6 hónappal végeztünk PSA-laborvizsgálatot. A cut-off level-t 0,1 ng/ml-ben határoztuk meg. Eredmények: Az eredmények alapján megállapítható volt, hogy a COVID-19-pandémia idején a prosztatatumoros betegek előrehaladottabb betegséggel, magasabb preoperatív és posztoperatív Gleason-score értékekkel és előrehaladottabb patológiai stádiummal kerültek műtéti ellátásra osztályunkon. A pT3-stádiumú lokális kiterjedtség 2,97-szor gyakoribb volt a járvány alatti időszakban operáltaknál. Ebből következően a pozitív sebészi szél aránya is magasabb volt a pandémiás csoportban. A perineurális terjedés 2,57- szor, a limfovaszkuláris invázió 2,37-szor fordult elő többször. Szignifikáns eltérést mutatott a korai biokémiai relapszus aránya is, amely szintén a járvány alatti csoportban volt a magasabb. Megbeszélés: A fenti eredmények rámutatnak arra, hogy pandémia idején a betegek rákspecifikus gyógyulási esélye kisebb. A szűrővizsgálatok csúszása, illetve elmaradása miatt a páciensek eleve később kerülnek kuratív ellátásra.
Ellul on Biblical Violence
Authors: Bassac Christian
Published: May 2024

Jacques Ellul’s analysis of biblical violence is resolutely Christocentric: all manifestations of violence must be seen in the perspective of the Revelation in Christ. There are no subtypes of violence, and all manifestations of violence are expressions of necessity. In turn, violence, which stands in stark contrast with language, leads to servitude and this circle can be broken only by the freedom brought by the violence of God’s unconditional love. This love is both the ultimate spiritual violence, as it is a victory over the necessity of death, and the promise of universal salvation.
After Babel, the Horizontal War: City and Technique in Jacques Ellul
Authors: Gaskin Benjamin
Published: May 2024

Jacques Ellul is best known for his The Technological Society (1954), which outlines a sociological treatment of Technique; that is, the total technical phenomenon including but extending far beyond machines. Lesser known are Ellul’s theological works, though these relate plainly to the sociological. Of particular relevance to Technique is his theological treatment of civilisation in The Meaning of the City (1970). These two texts stand alone and yet, read together, are mutually illuminating. The present paper will follow this light from the ancient City to the Technique of modernity. This will entail first a focus on four Scriptural cities: Enoch, Resen, Babel, Nineveh. The way will then proceed via a literary route, through Cormac McCarthy’s Blood Meridian, in which the abstractions here discussed are rendered palpable as flesh and blood. This detour will attend to those aspects of war and scalp-hunting which are central to McCarthy’s text, especially in light of the epistemic enterprise of one of modern literature’s most memorable characters: Judge Holden. The relation between the City and Technique will be followed by tracing the metaphysics of inscription which is a corollary to the project of epistemic legibility that underpins the movement of Technique. This enterprise will be understood as a confluence of Babel and Nineveh, a spiritual war that seeks to exclude God by enfolding the totality of existence into a humanly-determined order. The relation between the city, this process of inscription, and the nature of Technique will then be discussed.
The Limits of the Ideology of Efficiency in the Field of Education: Jacques Ellul and Simone Weil
Authors: Coccimiglio Cristina
Published: May 2024

This article investigates the topic of “violence” determined by technical ideology, dwelling on Jacques Ellul’s reflection on schools and universities. Ellul’s condemnation seems to foreshadow the knowledge crisis and the perversion requiring that educational systems be permeated by the assertion of the logic of efficiency, which results in sacrificing content and the ability to select, to verify sources, to elaborate divergent visions, asserting a self-referential reasoning that swallows differences and cancels “multiplicity” for the benefit of dogmatic interpretations. It may be that Simone Weil’s ethics of attention could help counter this shift.
Birds of the Air and Winged Creatures: An Ironic Critique of Surveillance in Ecclesiastes and an Ellulian Ethic of Language, Love, Fear, and Freedom
Authors: Morelli Michael
Published: May 2024

First, this article introduces the person and work of Jacques Ellul and highlights important aspects of his writing on surveillance, power, and violence. It shows that Ellul’s critique of surveillance predates the work of other critics of surveillance such as Michel Foucault, Gilles Deleuze, and Giorgio Agamben. This provides a conceptual sociological frame for the more philosophical, theological, and ethical work provided in the conclusion. Second, this essay engages Ellul’s reading of Ecclesiastes, as provisionally demonstrated here, to uncover the wisdom of this curious scriptural text that can help individuals and groups to think and live well in surveillant environments.
Some new midpoint and trapezoidal type inequalities in multiplicative calculus with applications
Authors: Xie Jianqiang , Muhammad Ali , Thanin Sitthiwirattham
Published: May 2024

In this paper, we use multiplicative twice differentiable functions and establish two new multiplicative integral identities. Then, we use convexity for multiplicative twice differentiable functions and establish some new midpoint and trapezoidal type inequalities in the framework of multiplicative calculus. Finally, we give some applications to special means of real numbers to make these inequalities more interesting for the readers.
Normality through sharing of pairs of functions with derivatives
Authors: Charak Kuldeep , Kumar Manish , Singh Anil
Published: May 2024

Let F ?M(D) and let a, b and c be three distinct complex numbers. If, there
exist a holomorphic function h on D and a positive constant ? such that for
each f ? F , f and f ? partially share three pairs of functions (a, h), (b,
cf ) and (c, df ) on D, where cf and df are some values in some punctured
disk D* ?(0), then F is normal in D. This is an improvement of Schwick?s
result [Arch. Math. (Basel), 59 (1992), 50-54]. We also obtain several
normality criteria which significantly improve the existing results and
examples are given to establish the sharpness of results.
Functional differential inclusions with maximal monotone operators and nonconvex perturbations
Authors: Aitalioubrahim Myelkebir , Raghib Taha
Published: May 2024

In this paper, we study the existence of solutions for functional
differential inclusions governed by time-dependent maximal monotone
operators with nonconvex perturbations depending on all the variables.
Topological equicontinuity and topological uniform rigidity for dynamical system
Authors: Kumar Devender , Das Ruchi
Published: May 2024

In this paper, we study topological equicontinuity, topological uniform
rigidity and their properties. For a dynamical system, on a compact, T3
space, we study relations among the set of recurrent points of the map, the
set of non-wandering points of the map and the intersection of the range
sets of all iterations of the map. We define topological version of uniform
rigidity and show that on a compact and T3 space any dynamical system is
topologically uniformly rigid if it is first countable, almost topologically
equicontinuous and transitive or it is second countable, topologically
equicontinuous and has a dense set of periodic points. We show that a
topologically uniformly rigid dynamical system, on a compact, Hausdorff
space, has zero topological entropy. Moreover, we provide necessary examples
and counterexamples.
Hyperbolic Ricci soliton on warped product manifolds
Authors: Azami Shahroud , Fasihi-Ramandi Ghodratallah
Published: May 2024

In this paper, we investigate hyperbolic Ricci soliton as the special
solution of hyperbolic geometric flow on warped product manifolds. Then,
especially, we study these manifolds admitting either a conformal vector
field or a concurrent vector field. Also, the question that:? whether or not
a hyperbolic soliton reduces to an Einstein manifold?? is considered and
answered. Finally, we obtain some necessary conditions for generalized
Robertson-Walker space-time to be a hyperbolic Ricci soliton.
Compactness of boundary value problems for impulsive integro-differential equation
Authors: Beddani Moustafa , Beddani Hamid
Published: May 2024

In this paper, we establish sufficient conditions to show the compactness of
solution set of boundary value problems for impulsive integro-differential
equation using ?-Hilfer fractional operator in a appropriate Banach space.
The method we use to show our result is based on fixed point theorems for
Meir-Keeler condensing operators via measure of non-compactness, an example
is presented to illustrate our method.
Existence and Mittag-Leffler-Ulam-Stability results of sequential fractional hybrid pantograph equations
Authors: Houas Mohamed , Abbas Mohamed , Martínez Francisco
Published: May 2024

In this present work, the existence and uniqueness of solutions for
fractional pantograph differential equations involving Riemann-Liouville and
Caputo fractional derivatives are established by applying contraction
mapping principle and Leray-Schauder?s alternative. The Mittag-Leffler-Ulam
stability results are also obtained via generalized singular Gronwall?s
inequality. Finally, we give an illustrative example.