bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluar un desastre. Procedimientos de la Monarquía Hispánica tras el Terremoto de Lisboa de 1755: la Orden Circular del 8 de noviembre
Authors: Peregrín Pizarro Jaime
Published: October 2022

La mañana del día 1 de noviembre de 1755 la tierra tembló como nunca antes lo había hecho a poco más de 300 km al sur de Lisboa. Con una magnitud cercana a 9 en la Escala Richter, el temblor y el posterior tsunami arrasaron la capital portuguesa y buena parte de la costa atlántica peninsular y norteafricana. En este trabajo pretendemos explicar y analizar la primera respuesta política que se dio, desde la monarquía hispánica, al desastre natural, a través de la que conocemos como Orden Circular del 8 de noviembre. Un documento real en forma de encuesta que buscaba aglutinar toda la información de daños y fallecidos de las más de mil ciudades y entidades locales del reino. Este gran corpus documental se acabaría convirtiendo en una de las primeras encuestas macrosísmicas de la historia y se constituirá como modelo para el análisis de daños de los terremotos. Finalmente, también analizaremos un modelo similar de recepción de información articulado en 1756 en Portugal, comparándolo con la Orden Circular de Fernando VI.
Situating the Ecological in Dionne Brand’s Ossuaries
Authors: Aiyegbusi Titilola
Published: October 2022

What does it mean to read a poem about anti-Blackness as ecopoetics? How do we account for the ecological in such a work? How does this kind of reading unsettle the notion that ecological literatures are tethered to the environment? These are the questions I tackle in this paper as I undertake a reading of Dionne Brand’s Ossuaries as ecopoetry—a poem that explores the entanglements between the human and nonhuman worlds. I argue that through this poem, Brand pushes against such simple definitions of ecocritical works as focused on the impact of human activities on the environment. Her work suggests that woven into the fabric of the narratives that govern such activities are evidence of the destruction of marginalized bodies. As such, I approach Ossuaries from the angle of the key elements identified by scholars like Lawrence Buell, Laura-Gray Street, and Ann Fisher-Wirth as evident in ecological literatures. I examine how Brand deploys these features in her poem, using them to nudge us towards exploring Black histories in the context of what Kathryn Yusoff calls “geologic narratives.” I contend that these features situate Ossuaries within the context of ecopoetics, and therefore allow us to critique the impact of Anthropocenic origin narratives on both the environment, human body, and human history specifically, Black histories.
Offences and punishments in the workplace
Authors: Juhász Tímea , Kálmán Botond , Tóth Arnold
Published: October 2022

It is no longer a question today that in many cases employees find themselves in a situation where either they or their environment believe that they have committed a misdemeanor or sin at work. The perception of sin can depend on a number of factors, such as the particular organizational culture, management, employee preferences, the degree of trust in the organization, and so on. There are cases where we judge the same sin differently, making the severity and extent of the penalties involved vary. The present study examines workplace offenses and subsequent employer penalties and their impact. The researchers did not focus on illegal acts, but on those that violate moral standards or affect an employee's professional development and ability to advance in the workplace. The analysis made a distinction between misdemeanors that came to light and those that did not. The test results confirmed the following. The employees are more critical of their own faults than the employer, and this is especially true of moral faults. People experience sin and punishment differently by gender and age.
Opportunities and threats of digital transformation of business models in SMEs
Authors: Straková Jarmila , Talíř Milan , Váchal Jan
Published: October 2022

The importance of business models for small and medium-sized enterprises (SMEs) in terms of their competitiveness and sustainability is undoubtedly growing. The global Covid-19 pandemic even strengthens this trend. The degree of digitalization of corporate processes becomes the SME stability and development limitation. The paper submitted presents the results of research focused on the issue of digital transformation of business models on a test sample of 496 SMEs (out of which 214 operate in the manufacturing sector and industry and 218 are included in the services sector) using the method of dimensionality reduction and logit regression. The main output from the solution valid for both tested sectors is considered insufficient setting, management and evaluation of corporate processes. This applies to the main value-creating processes (input and output logistics, production, marketing and sales, service and other ancillary services) and supporting processes (purchase, scientific and technological development, human resources management and company infrastructure). In terms of the achieved degree of process digitization, an imbalance was found between the main value-creating processes and supporting processes. Investment in value-creating and supporting corporate processes are not considered an important factor for any of the sectors due to the high sensitivity of investments to the size and specialization of companies. In contrast, the higher perceived need for value chain digitization in both tested sectors, especially in the case of manufacturing and industry, is considered a very positive output. This proves the need for the digital transformation of companies and its positive impact on their profitability and competitiveness.
Impact of teleworking on shopping habits during the COVID-19 pandemic in Hungary
Authors: Lipták Katalin , Musinszki Zoltán
Published: October 2022

The COVID-19 pandemic resulted in a sudden and unprepared switch to teleworking and home office in many workplaces and job functions. The use of teleworking in Hungary was significantly below the European average until the emergence of the coronavirus, which forced many people into this situation. Curfew restrictions have led to a complete lack of separation between work and private life for some workers, with several advantages and disadvantages. This paper aims to analyse the impact of the COVID-19 pandemic on changes in trade patterns, as confirmed by a questionnaire survey. The research is based on a questionnaire about shopping habits during the home office period. The hypothesis of the authors is that the persistence of the home office, elimination of travel for work, constant online presence, fear of the virus, and the lockdown have also significantly changed shopping habits. The survey showed that a large proportion of respondents tried to reduce the amount of personal contact during the pandemic period and most of them turned to online solutions for safety reasons. About online purchases, many respondents indicated doubts as to quality and a lack of confidence in the product they were buying. However, the positive experience gained during the pandemic period is likely to influence future purchasing habits for the majority.
Entrepreneurship research in Central and Eastern Europe: A systematic literature review and bibliometric analysis
Authors: Głodowska Agnieszka , Wach Krzysztof
Published: October 2022

Entrepreneurship has a rich tradition in the history of economic thought, but Central and Eastern European (CEE) researchers are latecomers. The socialist or communist economic systems discriminated against the entrepreneurial activity. This article aims to supplement the knowledge about the state, intensity, and research trends on entrepreneurship in CEE countries. The systematic literature review covers over 30 years (1980-2021). The bibliometric analysis was conducted using the VOSviewer software. The regional output in quantitative terms is relatively smaller in comparison to the global academia, although it addresses basically the same topics as the world literature. CEE researchers undertake, in principle, the same research threads as the entire academic community worldwide. CEE researchers publish their work on Central Europe mainly in journals of regional publishers. The two currently leading regional scientific journals on entrepreneurship are Entrepreneurship and Sustainability Issues (Lithuania) and Entrepreneurial Business and Economics Review (Poland). Although, the history of entrepreneurship research in Central and Eastern Europe dates back to the beginning of the economic transition in the early 1990s, but the intensification of publications from this region in Web of Science has been observed since the mid-2000s.
Prediction of business cycle of Poland
Authors: Tkacova Andrea , Gavurova Beata , Kelemen Katarina
Published: October 2022

The paper is focused on the construction of a new composite indicator intended to predict the economic cycle of Poland and its comparison with the existing CLI used by international institutions such as OECD and Eurostat. In part, this research is also dedicated to monitoring the partial advance cyclical indicators that make up the CLI components and their changes over time. The paper explores 62 qualitative and quantitative economic indicators of Poland and their relationship to the development of monthly GDP at constant prices in three different time periods: 2005 to 2021, 2010 to 2021, and 2016 to 2021. A modified OECD method is used to select the cyclical component of time series using the Hodrick-Prescott filter and subsequently employ cross-correlation of the variables with the cyclical component of GDP. The constructed CLI can predict the evolution of the CLI one month ahead with a cross-correlation level of 0.879 under equal weights and 0.877 under different weights. Research has shown that there is no significant change in the composition of the CLI for the prediction of the economic cycle of Poland when using the established methodology.
Staurolemma omphalarioides (Pannariaceae, Ascomycota), a new species and genus for the lichen flora of Russia from Abrau Peninsula (North-Western Caucasus)
Authors: Urbanavichus Gennady P. , Urbanavichene Irina N. , Simakova Ulyana V. , Moskalenko Victoria N.
Published: October 2022

The genus Staurolemma Körb., represented by the species S. omphalarioides (Anzi) P. M. Jørg. et Henssen, identified both by morphology and using DNA barcoding (ITS1-5.8S-ITS2 gene), is reported for the first time for Russia, based on materials collected in the North-Western Caucasus in the Utrish Reserve on the Abrau Peninsula. The genus Staurolemma is widely distributed in the tropics and subtropics, and only one species S. omphalarioides, has a Mediterranean-Atlantic area. As in the Mediterranean basin, in the Abrau Peninsula, the species is confined to warm and humid habitats on the Black Sea coast, where it grows in sub-Mediterranean plant communities, in oak-juniper and juniper-pistachio forests, on the trunks and branches of deciduous trees, mainly on Pistacia mutica Fisch. et C. A. Mey. and Quercus pubescens Willd. Description and photo of species are given with a discussion on their taxonomy and distribution. For some studied specimens, new rITS sequences were generated and their GenBank accession numbers are provided.
Phytocoenotical behaviour of nemoral and boreal-nemoral plant species in taiga zone communities
Authors: Kucherov Ilja B. , Zverev Andrey A.
Published: October 2022

Phytocoenotic behaviour of 14 nemoral or boreal-nemoral vascular plant species is analyzed in the middle- and southern-taiga subzones in comparison with that in the broadleaved-forest zone, based upon the set of 1669 relevés made in European Russia in 1996–2018. The nemoral species are mainly represented by shadow mesoeutrophic plants from the “corteges” of Tilia cordata s. l. and Fagus sylvatica. The more light-demanding plants from the Quercus robur “cortege”, either mesotrophic, or mesoeutrophic, more often demonstrate the boreal-nemoral type of zonal distribution. In the boreal-forest zone, linden and beech companions are typical for the southern-boreal nemoral-herb / sorrel spruce (Picea abies s. l.) forests on placors as well as the valley / riparian tall-herb forests, including the middle-boreal ones. The oak companions also inhabit grass-feathermoss pine (Pinus sylvestris) forests, besides the spruce forest types mentioned. Species from all the named “corteges” are also common in the small-leaved forests. The Betula companions which grow together with the nemoral plants in boreal forests could also be subdivided into the two florogenetical groups, namely a) the boreal, originally subalpine plants and b) the boreal-nemoral ones, originally oak companions. Species from the latter group often become widespread and dominant in the small-leaved forests; a good example is provided by Aegopodium podagraria. The rank correlation (Spearman rS) analysis shows the projective cover increase is connected with either the growing season warmth supply, or the climate oceanicity for both nemoral and boreal-nemoral species. These effects are most sound in the placor community sequence from broadleaved forests to sorrel and then bilberry-feathermoss spruce ones but weakened in the tall-herb forests on rich soil and completely levelled in the aspen (Populus tremula) forests. Carbonate bedrock outcrops contribute to nemoral species survival in the areas they inhabited during the climatically favourable epochs; they also favoured the migration of these species during the interglacials. Individualization of coenotic patterns of nemoral species at their distribution limits does not contradict to joint occurrence of such plants in relict / extrazonal locations.
Floristic findings of adventive species in the Novosibirsk Region
Authors: Zykova Elena Yu. , Shaulo Dmitry N. , Pankova Tatyana V. , Krivenko Denis A.
Published: October 2022

New adventive species for the Novosibirsk Region are reported: Artemisia ludoviciana Nutt., Galium aparine L., Heliopsis helianthoides (L.) Sw., Ipomoea purpurea (L.) Roth., Lamium maculatum (L.) L., Lysimachia verticillaris Spreng., Malva moschata L., Phalaris canariensis L., Viscaria vulgaris Röhl. New localities of rare adventive species Alcea rosea L., Berberis vulgaris L., Parthenocissus quinquefolia (L.) Planch., Scutellaria altissima L., Sedum acre L., Thladiantha dubia Bunge were noted. For each species, its range is given, the distribution in the regions of Siberia is indicated.
New and rare adventitious species of vascular plants in the Sverdlovsk Region
Authors: Zolotareva Natalya V. , Podgaevskaya Elena N. , Dubrovin Denis I.
Published: October 2022

The article provides an information about the finds of six adventitious plant species in the Sverdlovsk Region, two of them are new to the flora of the region (Hesperis pycnotricha Borbás et Degen., Nepeta sibirica L.). Four species (Lotus corniculatus L., Silene dichotoma Ehrh., Urtica cannabina L., Vicia amoena Fisch.) were previously known from 1–2 localities in the Sverdlovsk Region and are rare adventitious species not only in the region, but also in adjacent territories. The presented information about new localities of adventitious species will become the basis for monitoring their distribution in the studied region in particular, and in the Urals as a whole.
IT és műszaki tudományok a hazai innováció élvonalában : A vállalatok kutatás-fejlesztési tevékenységének minősítése 2012-2021 között és a minősítés elmulasztásának veszélyei
Authors: Huszák Loretta , Szitáné Kazai Ágnes , Andó Marcell
Published: October 2022

Az innováció meghatározó szerepet játszik a nemzetgazdaságokban, ösztönzésére széles körben alkalmazhatók eszközök. A ta-nulmány nemzetközi áttekintés keretében tárgyalja az innovációösztönzést, a vállalatok számára elérhető adó- vagy adóalap-tí-pusú kedvezményeket, majd bemutatja a hazai innovációösztönzés rendszerét. E rendszer meghatározó eleme a kutatás-fej-lesztési tevékenység tíz éve bevezetett hatósági minősítési eljárása. A vállalatok középpontba helyezését a K+F és innováció területén játszott meghatározó szerepük indokolja, amit a KSH nyilvános statisztikai adatainak elemzésével támasztottak alá a szerzők. Kutatásuk hiánypótló, mivel az SZTNH nem publikus adatbázisának kiértékelése alapján elemzi a vállalati kutatás-fej-lesztést. A tanulmány két megközelítést ötvöz, a felülről, szisztematikusan elemzőt és az alulról, esettanulmányként értékelőt. Erőssége, hogy egy tipikus K+F cég esetpéldáján keresztül mutatja be az adóalap-kedvezmény alkalmazását, a minősítés igény-bevételének előnyeit, elmulasztásának kockázatait. Legfőbb megállapítása, hogy a K+F minősítés rendszere szilárd, alkalmazása előnyös a vállalkozások számára. A hazai innováció éllovasai a statisztikák alapján az IT és a műszaki szektor.
Maker-based Serious 3D Game Authoring Tool for Cultural Heritage Education
Authors: Abdulrazic Mostafa Osama Mostafa , Sanzana Mirza Rayana , Ng Kher Hui
Published: October 2022

As globalization and internationalization are taking place, it has become necessary to preserve one’s cultural heritage. In an individual’s personality, culture plays a substantial role and by educating each other about one’s culture, better cultural inclusion and respect are achieved. For better equality and inclusion within communities as mentioned by United Nations 17 Sustainable Development Goals, an engaging yet effective way of cultural awareness should be focused on. However, as younger generations are the future of a community, proper digital technologies should be utilized to make them engagedand entertained including benefiting the main objective of cultural heritage preservation. This research gathers appropriate design guidelines by letting users play a serious cultural Internet of Things (IoT) game focusing on a UNESCO Heritage Site in Malaysia and then validating a serious 3D game authoring tool by interviewing experts. The aim of this research is to design and develop an effective and innovative serious 3D game authoring tool with which anybody i.e., even non-experts can make their own game to share their cultural heritage story with others while playing a game themselves. Furthermore, this research also attempts to integrate interactive technologies such as IoT and haptic feedback technology such as Leap Motion, and UltraLeap 3Di into the game authoring tool. Finally, this research will do a case study with a school and a museum to validate the serious 3D game authoring tool and how it was perceived and accepted by the required stakeholders.
An examination of conscious awareness and problem solving skills with demographic and psychological variables
Authors: Tatoğlu Semanur , Birkök M. Cüneyt
Published: October 2022

The aim of this study is to examine the relationship between mindfulness and problem solving skills in terms of cognitive psychology approach and the effect of some independent vartables. Relational survey method was used in the study. The sample populatton consisted of 125 third and fourth year students of the Faculty of Educatton who were determined through disproportionate element sampling. The data collection tools used were "Personal Evaluation Ouestionnaire", "Mindfulness Awareness Scale (MBAS)" and "Problem Solving Inventory (PSB". For data analysis, t-test analysis, one-way analysis of vattance (ANOVA) and Pearson moment corfrelatton analysis were used.
In terms of the findings, no telattonship was found between mindfulness and problem solving skills. Demogtaphic characteristics and bemg a numerical or verbal major had no effect on mindfulness and problem solving.
Participants who were traumatized or had psychological complaints had lower levels of //7d/0/ness. The mindtulness levels of partikipants whose life philosophies and lives were in harmony were found to be high. Participants with persistent iİlnesses perceived themselves as more inadeguate in problem solving skills. Participants who have received or are receiving psychotherapy process consider themselves more competent in problem solving. It was found that as the participants' contributton to their own education plans decreased, they considered themselves more ınadeguate in problem solving skills. Participants who were asked for help to solve problems considered themselves more competent in problem solving.
As a result, significant relattonships were found between some vartables and mindfulness and problem solving skills. No direct relationship was found between mindfulness and problem solving skills.
Evaluation of Soil Compaction in Building Construction Projects
Authors: Diana Willis , Hartono Edi , Muntohar Agus Setyo , Wulandary Kartika
Published: October 2022

Soil compaction is one of the robust methods to improve the strength and compressibility of earthwork since the method is more efficient and practical. However, the compaction work must be evaluated to meet the maximum dry density (MDD) required from the standard laboratory compaction test. The common method used for the evaluation of field density is the sand-cone test. The main objective of this study was to investigate the relative compaction of the borrow-fill at the building construction using the sand-cone test. The test procedure followed the ASTM D1556/D1556M-15e1 and ASTM D698-12e2 for sand-cone test and Proctor standard compaction test. Statistical analysis was performed to evaluate the density and moisture obtained from the field test at Dorm and Research and Innovation Center (RIC) project construction. The probability (p) of the compaction work exceeded the 0,9 MDD or Rc=90% was calculated p=13% and p=18%. The results corresponded to average relative compaction (Rc) of 80% and 82% at the Dorm and RIC project, respectively, with the deviation standard of 8.69 dan 8.81.
Efficiency of the Use of Materials of Concrete Block against Rubble Stone on Shallow Foundation Works
Authors: Winarno Setya , Nuryanto Hari , Teguh Mochamad
Published: October 2022

Shallow foundation work with rubble stone material has several weaknesses, such as surface and shape irregularity and scarcity in a certain location. These weaknesses can be avoided through the use of concrete block material as a positive contribution for this research. This article provides the efficiency in the use of concrete blocks instead of rubble stones in shallow foundation work, by highlighting work productivity and total cost of work for both materials. Data is collected on a wall fence foundation work which implemented both materials successfully in Grogolan, Umbulmartani, Ngemplak, Sleman Yogyakarta Province. This research has revealed that the average productivity on concrete blocks and rubble stones is 0.799 m3/h and 0.590 m3/h respectively, in which there is a time efficiency that concrete block construction is 35,44% faster than that of rubble stone. Total cost of concrete block will be more expensive than rubble stone if the work volume is small, nevertheless it reaches a break-even-point at work volume of 11 m3, meaning that a cost efficiency of concrete block construction occurs if the work volume is more than 11 m3. Moreover, the implementation of concrete block has 4 intangible benefits i.e. saving space usage, minimum waste, ease of work, and more precise product.
Nonlinear Time History Analysis of Flat Slab Structure With OpenSees Navigator
Authors: Hasibuan Samsul A Rahman Sidik , Arfiadi Yoyong , Utomo Junaedi
Published: October 2022

Structural systems that do not use a beam as the main component were first developed by Turner in 1906. This structural system is better known as a flat slab. The flat slab structure is supported by column heads and drop panels, or without drop panels, or without column heads. Several building codes such as IS 456: 2000, ACI 318-08, ACI 318-19, EC 2:2004, and NZS 3101 (Part 1):2006 provide guidance for designing flat slab systems under gravity loads only. However, many flat slab buildings are also built in areas with high earthquakes which can cause the collapse of buildings due to earthquake loads. In this paper the 10-level flat slab building structure design results are analyzed using nonlinear time history response analysis with the help of OpenSees Navigator software using several earthquake records, namely Kobe (Japan, 1995), Imperial Valley (California, 1979) and Tabas (Iran, 1978) which has been adjusted to the design spectra of the city of Yogyakarta. From the results of the analysis using OpenSees Navigator, it was found that the story drift that occurred was still within the limits required in the regulations, so that the building being reviewed was still within the limits of life safety design.
Faktor Prioritas Peningkatan Kualitas Lingkungan Permukiman Nelayan Di Kelurahan Manggar Baru Kota Balikpapan
Authors: Wardani Mega Kusuma , Kadri Mohtana Kharisma
Published: October 2022

Kelurahan Manggar Baru berdasarkan Surat Keputusan Walikota Balikpapan Nomor 188.45-667 Tahun 2014 termasuk kedalam salah satu dari 12 Kelurahan yang ditetapkan sebagai permukiman kumuh di Kota Balikpapan dengan luas kawasan kumuh sebesar 50,64 hektar. Terjadi penurunan kualitas lingkungan yang disebabkan oleh minimnya ketersediaan infrastruktur, seperti pada jaringan drainase yang minim memadai sehingga tidak mampu mengendalikan limpasan air hujan dan menimbulkan genangan. Adapun permasalahan lainnya yaitu belum terdapat upaya dalam pengelolaan sampah meliputi pewadahan, pemilahan dan pengolahan skala lingkungan. Upaya yang telah dilakukan oleh Pemerintah Kota Balikpapan dalam mengatasi permasalahan adalah dengan mengimplementasikan program bantuan air bersih khusus MBR (masyarakat berpenghasilan rendah), namun belum terlayani secara keseluruhan dikarenakan prasarana yang kurang memadai. Implementasi program pembangunan septictank juga mengalami kendala yaitu belum meratanya program untuk seluruh masyarakat, sehingga terdapat masyarakat yang melakukan pembangunan dengan swadaya. Penelitian ini bertujuan untuk menganalisis faktor prioritas yang mempengaruhi peningkatan kualitas lingkungan permukiman nelayan di Kelurahan Manggar Baru dengan menggunakan metode analisis AHP (Analitycal Hierarchy Process). Hasil analisis AHP menunjukkan faktor prioritas yang mempengaruhi peningkatan kualitas lingkungan permukiman nelayan di Kelurahan Manggar Baru yaitu pada aspek lingkungan dengan nilai bobot sebesar 0,37 sedangkan untuk sub kriteria didapatkan faktor prioritas yaitu kondisi penyediaan air bersih dengan nilai bobot sebesar 0,28. Kata kunci: Kualitas Lingkungan; Peningkatan Kualitas Lingkungan; Permukiman Nelayan
Karakteristik Lingkungan Binaan Sekitar Halte Transit TransJogja
Authors: Putri Raisha Adila , Rakhmatullah Anita Ratnasari , Kusumodewi Diah Intan
Published: October 2022

TransJogja merupakan transportasi umum yang diciptakan dengan tujuan dapat mengurangi penggunaan kendaraan pribadi dan menggeser preferensi masyarakat untuk menggunakan moda transportasi umum sebagai moda utamanya dalam bermobilisasi. Transportasi ini telah dikembangkan sejak tahun 2008 dengan total jalur sebanyak 17 rute, 129 armada, dan 267 halte yang tersebar di Kota Yogyakarta, Kabupaten Sleman, dan Kabupaten Bantul. Penempatan simpul transit merupakan salah satu penentu peran halte di wilayah sekitarnya. Lingkungan Binaan yang compact di sekitar halte dapat menjadi atribut penting dalam peningkatan jumlah penumpang karena dapat menciptakan kawasan berbasis transit yang mampu mengurangi waktu perjalanan dan meningkatkan kemudahan pengguna. Penelitian ini membahas tentang karakteristik lingkungan binaan di sekitar Stasiun BRT dengan menggunakan metode kuantitatif berdasarkan 3 variabel yang diperoleh dari teori Transit Oriented Development (TOD). Kajian ini menunjukkan bahwa karakteristik halte transit TransJogja belum sepenuhnya menerapkan konsep dasar TOD yang dapat mengurangi kemacetan dan penggunaan kendaraan pribadi dalam bermobilisasi. Hal itu dapat terlihat dari karakteristik kepadatan penduduk, variasi guna lahan, dan kepadatan persimpangan yang ada.
Neadresné a neviditelné. K fenomenologické interpretaci motivu „neadresných jevů“ v biologii Adolfa Portmanna
Authors: Nitsche Martin
Published: October 2022

The study focuses on the interpretation of the motif of unaddressed phenomena in the dialogue between Adolf Portmann’s thought and phenomenology. It establishes the closeness between Portmann and
phenomenology, not in the foundation of phenomenality, but rather in employing nonaddressedness for interpreting phenomenality’s meaning. The concept of invisibility, especially in M. Merleau-Ponty and M. Henry, is considered as a phenomenological parallel to nonaddressedness. Both nonaddressedness and invisibility determine a layered perceptual environment that is based neither on representation of the perceived in a perceiving subject nor on an objective, causally interrelated system of functional relations.
Jako kus ztuhlé lávy. Polemika s historickými fakty v podání Stanislava Sousedíka
Authors: Švec Ondřej
Published: October 2022

A Riposte to Stanislav Sousedík’s View of Historical Facts
Domáce práce a tajomstvo hmoty. Polemická poznámka o Heideggerovej filozofii
Authors: Kuchtová Alžbeta
Published: October 2022

A Polemical Note on Heidegger’s Philosophy
Umbilical cord blood gases: probability of arterial or venous source in acidemia
Authors: Monneret Denis , Stavis Robert L.
Published: October 2022

Objectives

Umbilical cord blood gases (UBG) may be a critical element in the assessment of a depressed newborn infant but in some cases the arterial or venous UBG source is uncertain making clinical and/or medical-legal interpretation difficult. Objective: to estimate the probability of an arterial (ProbAS) or venous (ProbVS) UBG source depending on blood gas parameters in acidemic cases.

Methods

A total of 56,703 pairs of concomitant arterial and venous (CAV) UBG results assayed over an 8.8-year period were analyzed. Specimen pairs with preanalytical issues, duplicate source, or physiologically out-of-range or uninterpretable results were excluded. The 3,579 CAV-UBGs with an arterial and venous pH 6.70 to 7.25 were analyzed. Generalized additive model (gam)-based binomial logistic regressions were used to determine the ProbAS and ProbVS according to the blood gas parameters.

Results

The relative differences between arterial and venous medians were: pO2 ‒47%, pCO2 22%, pH −11%, and BD 4%. Below a median of 2.4 kPa, the lower the pO2, the higher the ProbAS. Above this value, the higher the pO2, the lower the ProbAS. An Excel worksheet is provided to calculate ProbAS and ProbVS from the regression model for different combinations of pH, pCO2, and pO2 values. Considering ProbAS and ProbVS above a cutoff 0.8, the model correctly identified the source in 56% of cases while 41% were indeterminant and 3% were erroneous.

Conclusions

The probability of an arterial or venous source of an umbilical blood gas can be estimated based on the pH, pCO2, and pO2 in most acidemic specimens.
Orthostatic intolerance and neurocognitive impairment in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Authors: Gaglio Caroline L. , Islam Mohammed F. , Cotler Joseph , Jason Leonard A.
Published: October 2022

Objectives

The Institute of Medicine (IOM 2015. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness. Washington: The National Academies Press) suggested new criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), which requires an endorsement of either neurocognitive impairment or orthostatic intolerance (OI) in addition to other core symptoms. While some research supports the inclusion of OI as a core symptom, others argue that overlap with neurocognitive impairment does not justify the either/or option. The current study assessed methods of operationalizing OI using items from the DePaul Symptom Questionnaire (DSQ-1 and -2) as a part of the IOM criteria. Evaluating the relationship between OI and neurocognitive symptoms may lead to a better understanding of diagnostic criteria for ME/CFS.

Methods

Two-hundred and forty-two participants completed the DSQ. We examined how many participants met the IOM criteria while endorsing different frequencies and severities of various OI symptoms.

Results

Neurocognitive impairment was reported by 93.4% of respondents. OI without concurrent neurocognitive symptoms only allowed for an additional 1.7–4.5% of participants to meet IOM criteria.

Conclusions

Neurocognitive symptoms and OI overlap in ME/CFS, and our results do not support the IOM’s inclusion of neurocognitive impairment and OI as interchangeable symptoms. Furthermore, our findings highlight the need for a uniform method of defining and measuring OI via self-report in order to accurately study OI as a symptom of ME/CFS.
A generalized stochastic SIR epidemic model with vaccination rules
Authors: Ma Zhihui , Qi Ting , Li Xiaohua
Published: October 2022

In this paper, a generalized stochastic SIR epidemic model with vaccination rules is presented and the threshold behavior of the proposed epidemic model is investigated. Firstly, the stability of the equilibrium of the deterministic system is considered and the corresponding conditions are obtained. Secondly, the threshold of a stochastic SIR system for the extinction and the permanence in mean of epidemic disease are investigated. The results show that a larger stochastic disturbance can cause infections diseases to go to extinction. However, for a relatively small stochastic disturbance, the evolutionary dynamics of the epidemic diseases are overwhelmingly depend on the incidence function. This implies that the stochastic disturbance and the incidence function play an important role in diseases control. To test the theoretical results, a series of numerical simulations of these cases with respect to different noise disturbance coefficients are conducted.
Le dossier du Patrice Grégoire dans les sources arabes
Authors: Mkacher Anis
Published: October 2022

Résumé en français

L’intégration de la région africaine au sein de l’Empire musulman fut l’occasion pour de nombreux historiens, géographes et autres érudits de s’intéresser à ces contrées, d’écrire une histoire de sa conquête et, par la suite, de dresser un tableau plus large qui englobait les aspects sociaux ou économiques de la région. Dans le présent travail, nous avons réalisé une enquête sur le Patrice Grégoire à travers les témoignages des récits arabes. Cette recherche est fondée sur un recensement de ces mentions et une analyse de leur contenu. L’objectif majeur est de comprendre l’apport de cette catégorie de textes à un épisode particulier de la conquête arabe de l’Afrique du Nord.
Computer-assisted orbital and midfacial reconstruction
Authors: Gellrich Nils-Claudius , Eckstein Fabian M. , Rahlf Björn , Lentge Fritjof , Spalthoff Simon , Jehn Philipp , Korn Philippe
Published: October 2022

Objective

Computer assistance has become indispensable in the reconstruction of the orbit and midface. Although these are key areas of an individual’s esthetic appearance, defects or deformities of the midface, especially those of the orbit, are treated diversely.

Methods

The aim of this article is to present the wide utility of computer-assistance in modern craniomaxillofacial surgery, including virtual planning, computer-aided design, guided surgery, navigational control, patient-specific implants, and quality control via image fusion.

Results

There have been rapid advances in both digital planning and manufacturing processes, with continual improvements.

Conclusions

Patient-specific implants have pushed the boundaries of reconstructive surgery in all surgical specialties.
Platelet-derived concentrates influence human keratinocyte proliferation in vitro and induce wound healing in a prospective case series of chronic wounds of different entities in vivo
Authors: Paulmann Anastasia , Strauss Sarah , Limbourg Anne , Vogt Peter M.
Published: October 2022

Objectives

Soft tissues defects can extend into the fat layer or even deeper and can cause significant clinical disadvantages like pain, infections, and loss of function. In particular, chronic wounds are difficult to treat, as split-thickness skin grafts (STSGs) have varying success rates. To improve wound healing in chronic wounds, the authors have studied the application of platelet-mediator concentrate (PMC) in a human keratinocyte culture model in vitro and of autologous platelet concentrates (PRP) in a combination with surgical procedures in vivo as second line therapy in patients with initially failed wound closure.

Methods

For in vitro testing on keratinocytes, a PMC was processed with a commercially available bedside system (ATR®, Curasan, Germany). In a clinical, nonrandomized study, five in-house patients with chronic wounds were treated using a combination of surgical debridement and autologous PRP. Time of healing as determined by epithelization as well as laser Doppler imaging to visualize blood flow was analyzed. Additionally, changes in ease of surgical wound closure were determined. Finally, the quality of life of patients was assessed using a validated questionnaire (clinicaltrials.gov # NCT03667638).

Results

In vitro testing shows a significant effect of PMC on keratinocyte proliferation in cell culture. Clinical studies showed that patients treated with PRP had initiation of wound closure, higher blood flow after PRP injection, and easier wound closure as well as improved quality of life.

Conclusions

The injection of platelet concentrates to treat chronic wound defects presents a favorable addition to treatment where single surgical procedures have failed and may improve current therapy options.
Thyroid surgery during the COVID-19 pandemic: difficulties – how to improve
Authors: Stefanou Christos K. , Papathanakos Georgios , Stefanou Stefanos K. , Tepelenis Kostas , Kitsouli Aikaterini , Barbouti Alexandra , Flindris Stefanos , Tsoumanis Periklis , Kanavaros Panagiotis , Kitsoulis Panagiotis
Published: October 2022

In December 2019, the new coronavirus infection (COVID-19) was declared a pandemic by the World Health Organization after rapidly spreading over the world in just a few months. All elective operations and nonemergency treatments have been postponed worldwide. However, some patients require surgical therapy as well, and the time spent waiting should not have a negative impact on the surgical outcome or disease course. Following the initial onset of the COVID-19 epidemic, instructions for proper and safe surgery for healthcare staff and patients should develop. Thyroid surgeries have decreased during the COVID-19 pandemic. Most of them can be postponed for a long time. Assessment of thyroid nodules recommends clinical examination, imaging studies, fine needle aspiration (FNA) and vocal cord examination. All these procedures are necessary, and sometimes they cannot be postponed. To determine the best timing, a thorough preoperative assessment should be undertaken, taking into account both oncological and anatomical features. Furthermore, COVID-19 status must be negative prior to any intervention, and hospital infrastructure must be ready to deal with the demanding situation.
Manganese-functionalized MXene theranostic nanoplatform for MRI-guided synergetic photothermal/chemodynamic therapy of cancer
Authors: An Dong , Wu Xin , Gong Yaolin , Li Wenlu , Dai Guidong , Lu Xiaofei , Yu Liangmin , Ren Wen Xiu , Qiu Meng , Shu Jian
Published: October 2022

Two-dimensional transition metal carbides and nitrides (MXenes) nanosheets with high photothermal conversion efficiency as well as photothermal stability can efficiently generate remarkable hyperthermia for photothermal therapy (PTT) of cancer. However, mono-MXenes cannot exhibit precise diagnosis and treatment to complete ablation of cancer cells in the PTT process. To overcome this dilemma, an “all-in-one” nanoplatform of titanium carbide (Ti3C2) MXene-based composite nanosheets is developed for magnetic resonance imaging (MRI)-guided multi-modal hyperthermia and chemodynamic tumor ablation, which was achieved by bonding of manganese ion on the surface of Ti3C2, and then was the functionalized nanosheets was modified by biocompatible PEG (Mn-Ti3C2@PEG). Due to magnetic and Fenton-like catalytic properties of Mn components, Mn-Ti3C2@PEG not only acted as the contrast agents for T1-weighted MRI (relaxivity value of 1.05 mM−1 s−1), but also converted cellular H2O2 into highly toxic hydroxyl radicals (·OH) mediated chemodynamic therapy (CDT). Moreover, Furthermore, Mn-Ti3C2@PEG can efficiently suppressed tumor-growth by PTT, due to the high photothermal conversion capability and photothermal stability. As a proof-of-concept model, the as-designed Mn-Ti3C2@PEG nanoplatform shows simultaneous MRI and dual-modal treatment for effective suppression of tumor with minimized side effects both in vitro and in vivo, indicating the great potential for clinical cancer theranostics.
Ophelia, more or less. Intersemiotic reinterpretations of a Shakespearean character
Authors: Percec Dana , Pungă Loredana
Published: October 2022

Ophelia, Shakespeare’s most tragic heroine, seems to be the character who has generated much more enthusiasm on the part of visual artists than on the part of literary critics. Consequently, there are a high number of artefacts, produced starting with the nineteenth century, which have been inspired by Hamlet’s unfortunate bride. Of this assortment of artefacts, we have picked some to deal with here. In analysing them, we survey through the history of the heroine’s representation in various visual media, comment on them from the point of view of intersemiotic translation, and verify, in broad lines, the hypothesis that they may be tributary to a number of factors ranging from some connected to the artist’s own identity and subjective interpretation of the original to factors connected to more general stereotypes, beliefs, attitudes, and socio-cultural trends.
pwrBRIDGE: a user-friendly web application for power and sample size estimation in batch-confounded microarray studies with dependent samples
Authors: Xia Qing , Thompson Jeffrey A. , Koestler Devin C.
Published: October 2022

Batch effect Reduction of mIcroarray data with Dependent samples usinG
Empirical Bayes (BRIDGE) is a recently developed statistical method to address the issue of batch effect correction in batch-confounded microarray studies with dependent samples. The key component of the BRIDGE methodology is the use of samples run as technical replicates in two or more batches, “bridging samples”, to inform batch effect correction/attenuation. While previously published results indicate a relationship between the number of bridging samples, M, and the statistical power of downstream statistical testing on the batch-corrected data, there is of yet no formal statistical framework or user-friendly software, for estimating M to achieve a specific statistical power for hypothesis tests conducted on the batch-corrected data. To fill this gap, we developed pwrBRIDGE, a simulation-based approach to estimate the bridging sample size, M, in batch-confounded longitudinal microarray studies. To illustrate the use of pwrBRIDGE, we consider a hypothetical, longitudinal batch-confounded study whose goal is to identify Alzheimer’s disease (AD) progression-associated genes from amnestic mild cognitive impairment (aMCI) to AD in human blood after a 5-year follow-up. pwrBRIDGE helps researchers design and plan batch-confounded microarray studies with dependent samples to avoid over- or under-powered studies.
Protection against H2O2-evoked toxicity in HT22 hippocampal neuronal cells by geissoschizine methyl ether via inhibiting ERK pathway
Authors: Hu Shengquan , Yang Lei , Ma Yucui , Li Limin , Li Zhiyue , Wen Xiaomin , Wu Zhengzhi
Published: October 2022

Oxidative stress is considered as an important mechanism underlying the pathology of neurodegenerative disorders. In this study, we utilized an in vitro model where oxidative stress process was evoked by exogenous hydrogen peroxide (H2O2) in HT22 murine hippocampal neurons and evaluated the neuroprotective effects of geissoschizine methyl ether (GME), a naturally occurring alkaloid from the hooks of Uncaria rhynchophylla (Miq.) Jacks. After a 24 h H2O2 (350 μM) insult, a significant decrease in cell survival and a sharp increase in intracellular reactive oxygen species were observed in HT22 cells. Encouragingly, GME (10–200 μM) effectively reversed these abnormal cellular changes induced by H2O2. Moreover, mechanistic studies using Western blot revealed that GME inhibited the increase of phospho-ERK protein expression, but not phospho-p38, caused by H2O2. Molecular docking simulation further revealed a possible binding mode that GME inhibited ERK protein, showing that GME favorably bound to ERK via multiple hydrophobic and hydrogen bond interactions. These findings indicate that GME provide effective neuroprotection via inhibiting ERK pathway and also encourage further ex vivo and in vivo pharmacological investigations of GME in treating oxidative stress-mediated neurological disorders.
Narrative Therapy Interventions for Depressive Symptomatology
Authors: Ocampo-Rigor Marie Therese W. , Fernandez Karina Therese G. , Tupaz Eileen F.
Published: October 2022

Problems with depression are among the most common and most debilitating psychological issues for which professional help is sought. Narrative therapy offers practices that have been found useful in assisting individuals with depressive thoughts, feelings, and behaviors. This article aims to contribute to the relatively limited literature by presenting a descriptive illustration of narrative therapy in the case of a client experiencing depressive symptoms. In particular, this article aims to demonstrate how the narrative therapeutic practices of externalization and documentation can be helpful for clients whose depressive symptoms have arisen as a result of the implicit acceptance and internalization of problematic norms, standards, and expectations. The article concludes that narrative therapy deserves serious consideration as an intervention for individuals who experience symptoms associated with depression.
Political Positioning of Religious Institutions in Comparative Perspective
Authors: Kwong Ying-ho
Published: October 2022

Existing literature has long debated on religious beliefs and democracy. However, the implications of religious institutions, which shall internally interpret faith and socialize followers and externally decide its political positions with authorities, have yet to be comprehensively explored. By adopting an inter-religious comparison in Hong Kong, this article argues that religious institutions decided to take different positions in response to democratization: Eastern religious organizations, including Buddhism, Taoism, and Confucianism, act as “state defenders” to legitimate government decisions at critical political moments. However, Christian organizations, including Catholicism and Protestantism, act as “state critics” to promote political justice. The Anglican Church is located at “in-between status” with pro-regime leaders but with pro-democracy followers. Consequently, Eastern religious institutions maintain close relations with the authorities, Christian leaders face criticisms from pro-regime associations, and intra-religious tensions within the Anglican Church are intensified. Theoretically, this article moves beyond that, from a “belief-based” perspective on how faith facilitates/hinders democratization to an “organization-based” perspective on how religious institutions choose their political positions in a sub-national hybrid regime. Empirically, this study examines how historical development in the pre-handover era contributed to different religion–state interactions in the post-handover period.