bluuebunny/crossref_metadata_2025 huggingface dataset:
Karakter Morfologi Talas (Colocasia Esculenta) Sebagai Indikator Level Kadar Oksalat Menggunakan Lensa Makro
Authors: Safriansyah Wahyu , Asman Asman , Ferdiana Nur Azizah , Noviyanti Atiek Rostika
Published: August 2022

Taro plant (Colocasia esculenta) is a type of tuber that contains many useful compounds, less fat and lots of vitamin A. The high calcium oxalate content in taro is an anti-nutritional and toxic which can cause itching in the mouth, burning sensation, irritation of the skin, mouth, and digestive tract. Taro processing reduced its oxalate levels, which also influenced the morphological changes observed by Scanning Electron Microscopy SEM imaging. There is no practical way to predict the oxalate level of taro, making it easier to predict its toxicity. The purpose of this study is to predict the level of taro toxicity based on its morphology using a more practical tool such as a macro lens combined with a smartphone. The prediction of oxalate levels in taro was carried out by combining taro morphological data based on SEM and several object images produced by a macro lens equipped with a smartphone. The image of the object captured with a macro lens is supplemented with a fluorescent procedure to enhance the sharpness of the image. The prediction of oxalate levels in taro using a macro lens is distinguished based on the number of dark sides (dots) in the imaging results. The accuracy of macro lenses is of course lower than SEM, but at least the results are used as an initial prediction of oxalate levels in taro.
ANALISIS KANDUNGAN MINYAK ATSIRI PADA KULIT BUAH LANGSAT DENGAN METODE KROMATOGRAFI GAS-SPEKTROMETER MASSA
Authors: Iyabu Hendri
Published: August 2022

Penelitian ini bertujuan untuk mengetahui kandungan minyak atsiri yang terdapat pada kulit buah langsat. Pada penelitian ini dilakukan ekstraksi minyak atsiri dengan metode destilasi uap dan kromatografi gas-spektrometer massa (KG-SM). Minyak atsiri yang diperoleh memiliki bentuk cair, berwarna kuning kecokelatan. Rendemen yang diperoleh sebesar 0,18%. Analisis komponen kimia minyak atsiri kulit buah langsat dilakukan dengan menggunakan Kromatografi Gas-Spektrometer Massa (GC-MS). Komponen terbesar minyak atsiri kulit buah langsat adalah senyawa diperoleh minyak atsiri yang termasuk dalam golongan senyawa Monoterpenoid dan sesquiterpenoid yaitu Bicyclo [2.2.1] Heptane,-5-Ethyl-1-Amine dan Bicyclo[4.1.0]Hept-3-En, 2-Isopropenyl-5-Isopropyl-7,7-Dimethyl
Transthoracic Lung Biopsy: A Retrospective Evaluation of the First Experiences in A Single Center
Authors: ÇORAPLI Mahmut , GÖKSU Mustafa , ALAKUŞ Hüseyin , BULUT Hacı Taner , GÜLYÜZ Ömer Cenap , PEHLİVANOGLU Burcin
Published: August 2022

Background: To evaluate our first experience on computed tomography (CT)-guided transthoracic lung biopsy and compare our results including complication rates, etc. with the literature.
Materials and Methods: Thirty-four CT-guided transthoracic biopsies in 33 consecutive patients with lung lesions using a 15 cm long 16 gauge semi-automatic (coaxial) biopsy needle were retrospectively evaluated. Age, gender, size of the lesion, location, distance to pleura, needle insertion angle, patient position, presence of emphysema and/or complications (pneumothorax and pulmonary hemorrhage), radiological findings before, during and after the biopsy,and pathological diagnosis were retrieved from patient files. The diagnostic success and failure of the method, and complication rates were noted.
Results: Pneumothorax and pulmonary hemorrhage were observed in 9 and 7 patients, respectively, and 4 patients had both. Application of a chest tube was necessary in only 4 patients (4 of 9 patients wirth pneumothorax). None of the patients with pulmonary hemorrhage required additional procedures. The biopsy sample was adequate for histopathologic evaluation in 32 patients with a diagnostic accuracy rate of 96.6%. The most frequent diagnosis was squamous cell carcinoma (11/33), followed by other types of primary lung tumors in 14, breast carcinoma metastasis in 2, and B-cell lymphoma in 1 patient.
Conclusions: Our rate of complication due to CT-guided transthoracic lung biopsy seems to be comparable with the literature. Pneumothorax and pulmonary hemorrhage may occur in up to one fifth/fourth but the management of these complications does not require additional procedures in the majority of patients, and the diagnostic accuracy rate is high.
A clinical case of a patient with mucocutaneous and musculoskeletal manifestations after COVID-19 vaccination
Authors: Dimova Zhaklin Rumenova , Boyadzhieva Vladimira , Stoilov Nikolay , Emin Soner , Nikolov Nikolay , Stoilov Rumen
Published: August 2022

With the onset of the global pandemic due to the new virus SARS-CoV-2 and the development of vaccines against it, various adverse events have been reported to them. We present a clinical case of a 53-year-old Caucasian woman who presented one week after Pfizer vaccination against SARS-CoV-2 with severe muscle weakness, myalgia in upper and lower extremities, alopecia 2 cm in diameter, and two mucosal ulcerations on lower lip. No deviations from the hematological, biochemical and immunological indicators were found from the laboratory tests carried out. Two weeks later, the patient developed total alopecia on the scalp. Due to the causal relationship with the administered vaccine, the patient was not given a second dose and a diagnosis of Systemic Connective Tissue Disease was not accepted. Six months later, recovery and partial hair growth was observed in the affected areas of the capillitium.

Alopecia areata is autoimmune in nature, with literature reporting initial or recurrent alopecia after vaccination. It is important that adverse events after vaccination are properly evaluated in order to choose a proper therapeutic approach.
STRATIFICATION OF KNEE OSTEOARTHRITIS: TO THE PROBLEM OF PHENOTYPES
Authors: Korochina Kristina , Chernysheva Tatyana , Korochina Irina , Krivotulova Irina , Averyanov Andrey , Stolbova Marina
Published: August 2022

The presented review is devoted to the actual problem of knee osteoarthritis (OA) stratification and consists of descriptive and systemic analysis parts. In the first part, the evolution of OA concepts and the development of phenotypic approach is reflected. It is noted that OA followed long path from age-related “wear and tear” to inflammatory disease with high heterogeneity, which triggered enormous number of attempts to group this disease in the last decade. As no unified approach has been proposed in its classifying, rheumatology has collected an abundance of ambiguous data obtained in studies on knee OA. Recent advances in phenotyping made obvious the need to systematize proposed earlier classifications and to evaluate their compliance with the modern concept, which was done in the second part of review. Systematic search strategy was used in the referenced databases MEDLINE/PubMed and Google Scholar without a time frame with the following keywords "osteoarthritis", "phenotypes", "classification", "subtypes", "subsets", "subgroups", "endotypes", and 58 different classifications were extracted, analyzed and stratified into the following boxes: phenotypes, endotypes, and other classifications. Among the proposed OA classifications, clinical groups were the most common, followed by structural, laboratory, molecular, genetic, and progression trajectories. Only few of proposed OA kinds can rightly be called phenotypes whereas most of classifications aimed to distinguish predictors or risk factors for this disease. It can be assured that the variety of accumulated information will soon lead us to novel approaches of phenotype-associated management strategy for OA patients.
POTENTIAL OF UMBILICAL CORD MESENCHYMAL STEM CELL (UC-MSC) IN THERAPY OF RHEUMATOID ARTHRITIS (RA)
Authors: Margareta Ferdiana Laura , Nugraha Yudhi , Nurcita Boenga , Fauziah Cut
Published: August 2022

Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation of the joints. Even RA usually found in elderly patients, however, it is possible to occur at a young age, such as juvenile rheumatoid arthritis (JRA), the most common type of arthritis in children and adolescents. Unfortunately, common conventional therapies given to patients with RA to modulate the immune response, including disease-modifying anti-rheumatic drugs (DMARDS) and nonsteroidal anti-inflammatory drugs (NSAIDs), found have limitation therapeutic effects in RA patients. Long-term use of these drugs will cause side effects and resistance to therapy. In recent years mesenchymal stem cells (MSCs) are highly recommended therapy. The therapy considered promising for curative action in RA patient due to potential as immunomodulators that MSCs can differentiate into various cell types and stimulate tissue repair. These cells also have strong chemotactic abilities because they can migrate to damaged tissues and act as an anti-inflammatory. Therefore, MSC potentially suitable for autoimmune therapy. In addition, many research evidences in clinical trials stating that there are no toxicity and side effects in the long term. One type of MSC based on its tissue source is umbilical cord mesenchymal stem cell which is believed to be the best among other types. This review discusses a UC-MSC-based therapeutic approach in children, adults, and the elderly focusing based on published clinical data and clinical trials for the treatment of RA that are currently ongoing.
Evaluation of Metabolic Syndrome in Egyptian Patients with Radiographic and Non-Radiographic Axial Spondyloarthritis (Cross Sectional Study)
Authors: Gado Souzan Ezzat , Elwan S. A. , El Sharkawy A. M. , El-Banna H. S.
Published: August 2022

Background: Axial spondyloarthritis is a chronic inflammatory rheumatic disease that has a great risk for metabolic syndrome. Our aim was to study metabolic syndrome (MetS) in radiographic and non- radiographic axial spondyloarthritis patients in Egyptian population. Methods: The cross-sectional study included 60 consecutive Ax-SpA patients aged 25-55 years fulfilling the Assessment of Spondyloarthritis International Society criteria; they were divided into 40 patients with radiographic and 20 patients with non- radiographic axial spodyloarthritis. MetS was assessed using new international diabetes federation definition. Results: The prevalence of MetS was higher in radiographic patients (37.50%) than non-radiographic axial spondyloarthritis (20%) (X2 = 0.170, P = 0.242) with significant differences between the two groups as regard triglycerides (p = 0.012*) and HDL cholesterol (p < 0.001*). Decreased HDL-cholesterol was the most frequent metabolic syndrome component with a prevalence of 66.66% (40 patients) in both groups. Conclusion: Metabolic syndrome was more prevalent in radiographic axial spodyloarthritis. Therefore, follow up of these patients is important for early detection of any cardiovascular events.
New therapeutic options for the treatment of ankylosing spondylitis.
Authors: Boyadzhieva Vladimira , Stoilov Nikolay , Geneva-Popova Mariela , Ivanova Mariana , Stoilov Rumen
Published: August 2022

The pathogenesis of spondyloarthritis (SpA) is multifactorial and involves multiple immune cells and cytokines that are signaled by Janus kinase (JAK). Inhibition of JAK signaling pathways has emerged as a new therapeutic option for patients with inflammatory joint diseases. Despite the proven effect of treatment with anti-IL-17, as well as TNFα inhibitors, some patients with ankylosing spondylitis cannot reach minimal disease activity or remission. This necessitated the development of a new class of molecules, and in recent years more and more clinical studies have proven their role in the treatment of both rheumatoid arthritis and ankylosing spondylitis. JAK inhibition is a promising therapeutic strategy for the treatment of SpA and its application has potential in patients with axial, polyarticular, or extraarticular manifestations of the disease in psoriatic arthritis and ankylosing spondylitis.

The present literature review aims to highlight the new therapeutic options offered by this class of target synthetic disease-modifying antirheumatic drugs and to summarize the clinical trial data for tofacitinib, upadacitinib and filgotinib reported to date.
Impact of Achyranthes aspera L. on Protein Profile in Impaired Wound Models
Authors: Baru C C , Talukdara A , Begum S A , Handique A K , Handique G K , J D Roy  , B Buragohaina
Published: August 2022

In the present study, comparative protein profile of granulation tissues of burn, diabetic and immunocompromised wounds treated with 5.0% (w/w) ointment of methanol extract of Achyranthes aspera was undertaken. Granulation tissue of A. aspera treated group showed expression of a protein with molecular weight 69.4 kD in burn wound and proteins ranging from high, medium and low molecular weight (61.0, 55.0 and 31.5kD) in diabetic and immunocompromised wounds. A. aspera treatment induced expression of a particular protein of molecular weight 31.5 kD in both diabetic and immunocompromised wound models, signifying that this particular protein might play a key role in A. aspera mediated wound healing in these two models. © 2011 IGJPS. All rights reserved
Synthesis of Novel Imidazoles as Potent Antimicrobial Agents
Authors: Jawaharmal  , Narwal Smita , Singh Gurvirender , Saini Dev Rishika
Published: August 2022

Imidazole is a heterocyclic compound with five membered unsaturated ring structure composed of 3 carbons and 2 nitrogen atoms at non–adjacent positions. Imidazole drugs have broad applications in many areas of clinical medicine. These are currently used as tools in pharmacological studies. The important therapeutic properties of imidazole related drugs have encouraged the medicinal chemists to synthesize and test a large number of novel molecules. In this investigation, it was of interest to synthesize 1-(2-bromophenyl)-2-phenyl-1H-phenanthro[9,10-d]imidazole, by reaction of substituted imidazole with bromine in the presence of acetic acid. Various derivatives i.e. 1-(2-bromophenyl)-2-phenyl-1H-phenanthro[9,10-d]imidazole, 1-(2-bromophenyl)-2-(2- nitrophenyl)-1H-phenanthro [9,10-d]imidazole, 1-(2-bromophenyl)-2-(4-chlorophenyl)-1H-phenanthro [9,10-d]imidazole, 1-(2- bromophenyl)-2-(4-styryl-phenyl)-1H-phenanthro [9,10-d]imidazole and 1-(2-bromophenyl)-2-(4-styryl-phenyl)-1H-phenanthro [9,10-d]imidazole were formed with respective yield of 74, 64, 73, 79 and 72%. The structures of the compounds have been established on the basis of spectral analytical data. All the derivatives have been screened for their antimicrobial activities at the 100µg/ml and 200µg/ml against Candida albicans. © 2011 IGJPS. All rights reserved
Formulation & Evaluation of Aceclofenac Fast Dissolving Tablets Using Foam Granulation Technique
Authors: Bahnassi Anas , Zidan Diana
Published: August 2022

Orally dissolving tablets (ODT) provides a patient compliance solution for patients swallowing difficulties. Foam granulation is a newer technique that promises better distribution of the granulating system and better properties of the produced tablets. Aceclofenac (anti-inflammatory and analgesic) was selected as the model drug. The poor hydrophilicity of the drug results in variable dissolution rate and poor bioavailability. In this study, we tried to prepare aceclofenac ODT using the newer technique and various types of disintegrants, glidants, and lubricants. The resulted tablets were evaluated for hardness, friability, weight variation, in vitro disintegration time, and wetting time. All the formulation showed acceptable disintegration time. It was concluded that the prepared aceclofenac ODT by foam granulation technique using selective range of excipients can provide a dosage form with better patient compliance and effective therapy. © 2011 IGJPS. All rights reserved
Suzuki Cross Coupling Reaction- A Review
Authors: Singh Gujral Sarbjeet , Khatri Smriti , Riyal Poornima , Gahlot Vinod
Published: August 2022

Suzuki cross coupling reaction is one of the most famous reaction in the field of chemistry. It is a very effective method for making carbon – carbon bonds. It has been extensively utilized in the synthesis of many carbon molecules including the most complex ones. It also find application in the synthesis of compounds of biological sources like (+)-dynemicin, Adragmacidin F, Flurbiprofen, Felbinac, Fenbufen, Difunisal, Aporphinoids, Oximidine II, Nemertelline, Gymnocin A, Palytoxin, Michellamine, CP263,114, Halenaquinone, Brevetoxin, Yuehchukene, caparratriene etc which have been synthesized using the same reaction along with some other organic compounds. The present review article emphasis on carbon-carbon bond formation via cross coupling reaction, mechanism and applications in a natural product synthesis. © 2011 IGJPS. All rights reserved
Ozone Therapy: A Milestone in the Treatment of Ailments
Authors: Singh Gujral Sarbjeet , Nand Pratibha , Vashist Neelam
Published: August 2022

Ozone therapy or Ozonated Autohemotherapy (O3-AHT) has been meticulously used for more than a century to improve cellular function and for quicker healing of diseased tissues. It involves administration of ozone as gas or in liquid form to kill the microorganisms. Furthermore, body provides more energy using oxygen and can eliminate wastes efficiently. Ozone is used by different health organizations for its disinfectant, antiseptic, quick healing properties, circulatory disorders, geriatric conditions, cancer, skin healing, AIDS, rheumatism/arthritis and in water treatment plants etc. It was found to be consistent safe, with minimal and preventable side effects. It should be introduced into the body in large quantities so that the singlet oxygen molecule which is unattached and freely circulating will attack all immature, sick and deformed foreign cells. Availability of ozone in gaseous state further limits its use; hence some special techniques should be designed through strong R&D input which can make this technique widely accepted. Initially ozone was believed to have treacherous effects, yet researchers alleged that it may have therapeutic benefits which directed researchers to study and synchronize its use with the current medical practices. © 2011 IGJPS. All rights reserved.
Designing, Development & Evaluation of Floating Acyclovir Tablets
Authors: Khatri Smriti , Ahmed Farhan Jalees , Drabu Sushma , Sarangi Babita
Published: August 2022

Floating Drug delivery system helps the drug to remain in stomach for longer periodof time and hence can release the drug. The aim of the present study was to develop a hydrodynamically balanced system of acyclovir as single-unit floating tablets. The tablets were prepared by direct compression technique, using polymers such as hydroxypropyl methylcellulose (HPMC K15M, K4M), guargum (GG), and sodium carboxymethylcellulose (SCMC), alone or in combination, Drug release of optimized formulation was fitted in to zero order, first order and higuchi models. It was found that the release followed Zero order kinetics. Good stability was observed for 6 months during stability studies. Thus, results of the current study clearly indicate, a promising potential of the Acyclovir floating system as an alternative to the conventional dosage form. © 2011 IGJPS. All rights reserved.
R (Begum) v Special Immigration Appeals Commission; R (Begum) v Secretary of State for the Home Department; Begum v Secretary of State for the Home Department [2021] UKSC 7, [2021] AC 765
Authors: Fripp Eric
Published: August 2022

N/A
Dynamic effects of temperature-dependent aberration factors on the beam quality of LD end-pumped lasers
Authors: Feng Chi , Dong Yuan , Jin Guangyong
Published: August 2022

Considering the temperature dependence of the thermal conductivity of the gain medium, the aberration factor of the thermal lens becomes a function of temperature. The influence of the aberration factor on critical spot size is analyzed, the actual value of critical spot size is recalculated, and the range of beam quality deterioration is re-pointed. An asymmetric flat cavity experiment is built, and a symmetrical flat cavity is used as the supporting experiment. The widened beam quality degradation range and the dynamic operating point of the fundamental mode beam are pointed out. Experimental results match the simulation.
GAMBARAN PENGETAHUAN TENTANG PENGARUH ROKOK ELEKTRIK TERHADAP KESEHATAN GIGI DAN MULUT PADA KOMUNITAS VAPOR DI KOTA PALEMBANG
Authors: Maharani Allicia , Wahyuni Sri , Hanum Nur Adiba
Published: August 2022

Latar Belakang : Rokok Elektrik dirancang untuk menghantarkan nikotin tanpa asap tembakau dengan cara memanaskan larutan nikotin, perasa, propilen glycol dan glycerin. Rokok elektrik dapat menyebabkan beberapa gangguan pada rongga mulut seperti perubahan struktur dan estetika gigi, melanosis rongga mulut, xerostomia, danp periodontitis. Umumnya rokok elektrik digunakan oleh kalangan milenial dan  menjadikannya sebagai gaya hidup yang ingin dicoba. Pengguna pemula hanya ikut-ikutan untuk menggunakan tanpa tahu dampak bagi kesehatan gigi dan mulut. Vaping dianggap lebih aman dibandingkan rokok konvensional karena tidak mengandung produk-produk  pembakaran yang berbahaya.  Hal ini menunjukkan bahwa  masih minimnya pengetahuan yang diterima oleh masyarakat tentang bahaya rokok elektrik. Tujuan: Untuk mengetahui gambaran pengetahuan tentang pengaruh rokok elektrik terhadap kesehatan gigi dan mulut pada komunitas vapor di kota Palembang. Metode: Deskriptif, Dilaksanakan pada bulan Februari 2021. Sample penelitian ini sebanyak 100 orang pengguna rokok elektrik di kota Palembang dengan analisa data Univariat. Hasil: Berdasarkan hasil penelitian didapatkan bahwa responden pengguna vapor yang memiliki pengetahuan tentang pengaruh rokok elektrik terhadap kesehatan gigi dan mulut dengan katergori baik sebesar 26%, dengan kategori sedang sebesar 10%, dan kategori kurang sebesar 64%. Simpulan: Sebagian besar pengguna rokok elektrik memiliki pengetahuan  tentang pengaruh rokok elektrik terhadap kesehatan gigi dalam kategori kurang sehingga perlu diberikan edukasi pada pengguna rokok elektriik.

 

Kata Kunci : Pengetahuan, rokok elektrik, kesehatan gigi dan mulut
HUBUNGAN KEBIASAAN MENGONSUMSI KOPI TERHADAP TERJADINYA STAIN
Authors: Khasanah Novi , Syahniati Tri , Mujiyati Mujiyati
Published: August 2022

Latar Belakang.Stain adalah warna yang menempel pada permukaan gigi yang terjadi karena adanya perlekatan warna makanan, minuman dan kandungan lain yang menyebabkan perubahan warna pada gigi. Kopi merupakan minuman hasil seduhan biji kopi yang telah disangrai dan dihaluskan menjadi bubuk, kopi banyak dikonsumsi setiap  harinya di seluruh dunia termasuk di Indonesia. Kebiasaan mengonsumsi kopi merupakan salah satu faktor penyebab terjadinya stain pada gigi yang diakibatkan oleh kandungan tanin, asam dan kafein di dalam kopi.

Tujuan.Untuk mengetahui hubungan kebiasaan mengonsumsi kopi terhadap terjadinya stain pada gigi.

Metode.Penelitian ini adalah penelitian cross sectional yang dilaksanakan pada bulan Januari-Maret 2021 terhadap 63 orang disalah satu RT di Kabupaten OKI. Kebiasaan mengonsumsi kopi diperoleh melalui wawancara menggunakan kuesioner, sedangkan stain pada gigi diukur melalui observasi

Hasil.Dari 63 orang sampel yang diperiksa didapatkan hasil bahwa sebanyak 49 orang (77,8%) masyarakat mengalami stain sedangkan 14 orang (22,2%) lainnya tidak mengalami stain. Pada uji Regresi Linier terhadap lamanya mengonsumsi kopi dengan terjadinya stain didapatkan hasil p = 0,00 Sedangkan pada uji regresi linier terhadap jumlah banyaknya kopi yang diminum dengan terjadinya stain didapatkan hasil p = 0,019

Kesimpulan.Kebiasaan mengonsumsi kopi mempunyai hubungan terhadap terjadinya Stain pada gigi.
Evaluasi Kegiatan Penimbunan Dan Pembongkaran Batubara Pada Stockpile Di Coal Handling Facilities PT. Rinjani Kartanegara
Authors: Baehaqi Pradipta , Dina Devy Shalaho , Sakdillah Sakdillah , Winarno Agus , Nugroho Windhu
Published: August 2022

Aktivitas pemuatan (loading) ke tongkang ditunjang oleh Barge Loading Conveyor (BLC) dengan kapasitas 800 ton /jam.  Tujuan penelitian ini adalah untuk  mengevaluasi kegiatan penimbunan dan pembongkaran batubara pada stockpile di coal handling facilities PT.Rinjani kartanegara Penelitian ini menggunakan metode studi lapangan, dalam  pengamatan dan analisis, langkah awal yang dilakukan adalah pengamatan dilapangan terkait kondisi aktual stockpile, aktivitas penimbunan dan pembongkaran batubara di stockpile, pengamatan implementasi manajemen FIFO, dan pengamatan operasi produksi dozer penunjang kegiatan di stockpile. Kemudian dilakukan analisis berdasarkan data primer dan data sekunder yang diperoleh pada periode penelitian. Hasil dari penelitian diketahui bahwa permasalahan yang terjadi pada stockpile yakni, bedding coal tipis pada area stockpile RK I dan terdapat genangan air pada sisi timur stockpile RK I. Pada kegiatan operasional penimbunan dan pembongkaran batubara, terpantau terlaksana dengan baik. Parameternya yakni tidak adanya antrian panjang dump truck, adanya pemisahan timbunan antar produk batubara, urutan penimbunan telah sesuai dengan skema penimbunan yang dicanangkan, daya tampung stockpile aktual yang mumpuni dalam menerima stock batubara, dan lebar jalan akses menuju stockpile telah sesuai dengan layout planning stockpile. Pada unit dozer Komatsu D85E-SS tipe rops canopy, D65P, Liebherr PR 734-4 penunjang operasional penimbunan dan pembongkaran batubara, diperlukan penambahan kapasitas blade dengan cara penambahan plat pada bagian upper frame, yang diharapkan dapat meningkatkan produktivitas dozer. Peningkatan produktivitas dozer akan berdampak terhadap kenaikan produksi crushing maupun loading.
Contribution of pelvic hot shower therapy to effectiveness in 2nd trimester medical abortions (Balsak's hot shower technique)
Authors: Balsak Deniz , Aksin Şerif , Ertekin Yusuf Haydar , Yılmaz Mehmet
Published: August 2022

Objective: This study aims to investigate the effects of the pelvic hot shower in missed second-trimester abortions.
Material and Methods: A total of 125 pregnant patients with fetal demise were included in this study. They were divided into two groups according to the treatment used to induce abortion. One group was treated with misoprostol only (n:74), and the other group received medical treatment and pelvic hot shower therapy (n:51). A pelvic hot shower application was applied when the patient's vaginal bleeding started. Hot water at 55-60 oC was applied to the pelvic region for 30 minutes.
Results: There was no difference between the two groups regarding age, body mass index (BMI), and gestational week. (p> 0.05) After the induction started, the duration of the abortion was 8.57 hours in the pelvic shower group and 12.97 hours in the misoprostol group. The difference of abortion times among the groups was statistically significant (p: 0.039*). The total dose of used misoprostol that caused vaginal contraction for abortionwas 396 mg in the patient with pelvic shower and 614 mg in the misoprostol group; the difference was statistically significant (p< 0.001). The  Visual Analogue Scale VAS score and analgesic requirements were significantly lower in the pelvic shower therapy group (p<0.05).
Conclusion: Pelvic hot shower application is an accessible, applicable, simple, effective, and inexpensive beneficial method for patients in the induced 2nd trimester.
ANALYSIS OF THE EFFECTIVENESS OF FACTORING RISK MANAGEMENT USING THE DUPONT MODEL
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russia, Kirillova Nataliya V.
Published: August 2022

The study proposed a methodological approach to assessing the effectiveness of specific financial risk management, combining qualitative risk management factors such as the complexity of risk management methods, scale, complexity, accuracy and timeliness and quantitative, such as expected losses, cost of risk, profitability of factoring operations, based on a three-factor modified Dupont model. The approach allows us to analyze the effectiveness of risk management to optimize the totality of transactions of a factoring company in compliance with the principle of risk management to control the risk appetite of the business.
THE IMPACT OF AN INVESTMENT AND INNOVATION PROJECT ON THE FINANCIAL CONDITION OF AN INDUSTRIAL ENTERPRISE
Authors:   Saint-Petersburg State University of Aerospace Instrumentation, St. Petersburg, Russia, Pokshivanova Olga P.
Published: August 2022

The implementation of an innovative project involves evaluating the effectiveness of the project and analyzing its impact on the financial condition of the organization in order to determine the potential of the project available to improve the financial situation of the enterprise. To do this, it is necessary to evaluate the values of the performance indicators of an innovative project and display the change in the financial position of the organization as a result of its implementation in order to obtain quantitative characteristics of the organization's gain from the integration of the project into the structure of the enterprise's assets that generate value. The importance of evaluating the effectiveness and analyzing the impact of an innovative project on the financial condition of an enterprise determines the importance of the topic.
NODAL PROBLEMS OF THE DEVELOPMENT OF THE AGRO-INDUSTRIAL COMPLEX OF RUSSIA AT THE PRESENT STAGE
Authors:   Russian Academy of National Economy and Public Service under the President of the Russian Federation, Moscow, Russia, Yarlykapov Abrar B.
Published: August 2022

The growth rates of the country's agro-industrial production in recent years have shown steadily high and steady growth. However, much remains to be done to transform the rural economy into a high-tech and socially oriented sphere.
COMPETENCE-BASED APPROACH IN HIGHER PROFESSIONAL EDUCATION
Authors:   Russian Academy of National Economy and Public Service under the President of the Russian Federation, Moscow, Russia, Miminoshvili Roman T. , Obukhova Larisa A. ,   Russian Academy of National Economy and Public Service under the President of the Russian Federation, Moscow, Russia
Published: August 2022

The article analyzes the competence approach in the system of modern higher professional education. The key concepts of “competence” and “competence” are analyzed, the essence of the competence approach is characterized, the difficulties of its implementation in the system of vocational education are revealed. The validity of the introduction of interactive teaching methods is considered.
Rough-set based learning methods: A case study to assess the relationship between the clinical delivery of cannabinoid medicine for anxiety, depression, sleep, patterns and predictability
Authors:   , Ashrafi Negi
Published: August 2022

COVID-19 is an unprecedented health crisis causing a great deal of stress and mental health challenges in populations in Canada. Recently, research is emerging highlighting the potential of cannabinoids’ beneficial effects related to anxiety, mood, and sleep disorders as well as pointing to an increased use of medicinal cannabis since COVID-19 was declared a pandemic. Furthermore, evidence points to a correlation between mental health and sleep patterns. The objective of this research is threefold: i) to assess the relationship of the clinical delivery of cannabinoid medicine, by utilizing machine learning, to anxiety, depression and sleep scores; ii) to discover patterns based on patient features such as specific cannabis recommendations, diagnosis information, decreasing/increasing levels of clinical assessment tools (GAD7, PHQ9 and PSQI) scores over a period of time (including during the COVID timeline); and iii) to predict whether new patients could potentially experience either an increase or decrease in clinical assessment tool scores. The dataset for this thesis was derived from patient visits to Ekosi Health Centres in Manitoba, Canada and Ontario, Canada from January, 2019 to April, 2021. Extensive pre-processing and feature engineering was performed. To determine the outcome of a patients treatment, a class feature (Worse, Better, or No Change) indicative of their progress or lack thereof due to the treatment received was introduced. Three well-known supervised machine learning models (tree-based, rule-based and nearest neighbour) were trained on the patient dataset. In addition, seven rough and rough-fuzzy hybrid methods were also trained on the same dataset. All experiments were conducted using a 10-fold CV method. Sensitivity and specificity measures were higher in all classes with rough and rough-fuzzy hybrid methods. The highest accuracy of 99.15% was obtained using the rule-based rough-set learning method.
Les mesures de température de Duhamel du Monceau de 1748 à 1780
Authors: Rousseau Daniel
Published: August 2022

Henri Louis Duhamel du Monceau a publié dans Histoire de l'Académie Royale des Sciences 40 articles sur des observations botanico-météorologiques réalisées dans son domaine de Denainvilliers, à 80 km au sud de Paris. Parmi celles-ci figurent des mesures de température réalisées trois fois par jour de 1748 à 1780. À partir de ces données, complétées, corrigées et transcrites en degrés Celsius, une série complète de températures journalières a été constituée. Cette série est comparée à celles réalisées à partir de mesures effectuées à la même époque par d'autres savants dans la région parisienne. Elle est utilisée pour illustrer quelques aspects du climat de cette période.

Henri Louis Duhamel du Monceau published in Histoire de l'Académie Royale des Sciences 40 articles on botanico-meteorological observations made at the Château de Denainvilliers, near Pluviers en Gâtinais, 80 km south of Paris. Among these are temperature measurements taken 3 times a day from 1748 to 1780. With these data, supplemented, corrected and transcribed in Celsius degrees, a complete series of daily temperatures has been built. This series is compared with measurements taken at the same time by other scientists in the Paris region. The series is used to illustrate some aspects of the climate of this period.
Symbols of the Sentient House of Usher: An Ecocritic Approach
Authors: Waithiru Antony Kago
Published: August 2022

This analysis is an attempt to examine usage of symbols in the ‘sentient’ house of Usher, a short story by Edgar Allan Poe. The short narrative is commonly renowned to as The Fall of the House of Usher. The paper has been premised on an ecocritic approach. Ecocriticism is a study that uses an interdisciplinary lens in its view on literature and environment. Mainly it concentrates on the relationship betwixt literary work and the surrounding, emphasizing on a habit of scrutiny that is vigilant to environmental issues. The main objective of such a reading is to highlight more ways of curbing environmental exploitation, minimizing or eliminating environmental violence, as well as end ecocide. This work evaluated Poes’ work and explored how symbolism has depicted nature and environmental concerns in his work. The analysis was guided by some of the major tenets of ecocriticism theory and hence, has been anchored on an ecocritic approach. Some of the tenets that guided it are death, tradition, and environmental rights. Symbolism is a technique of constructing literary and artistic work that is depicted through employment of symbols either because of interest in the craft and furnishing the piece work with an appealing literary fragrance or for whatsoever reason, such as portray environment. One of the main functions of symbolism in literary work is to censure society obscurely, securely, and devoid of any possible harm or victimization that may fall upon the author.
Hemorragia intramiocárdica tras infarto agudo de miocardio
Authors: Ruiz-Pizarro Virginia , Palacios-Rubio Julián , Gómez-Polo Juan Carlos , Martínez-Losas Pedro , García-de Castro Ana Bustos , Gómez-de Diego José Juán
Published: August 2022

La obstrucción microvascular y la hemorragia intramiocárdica son manifestaciones del daño por reperfusión que se encuentran con frecuencia en pacientes con oclusión aguda coronaria tratados con terapia de revascularización. Ambas se relacionan con el remodelado y función ventricular a largo plazo, así como el pronóstico. Se presenta un caso representativo de estas lesiones y su caracterización mediante diferentes técnicas de imagen cardíaca.
Candidemia con foco endovascular en injerto aórtico valvulado, diagnóstico por imagen en la era multimodalidad: resonancia magnética de corazón
Authors: Azcárate-Agüero Pedro María , Rábago-Juan Aracil Gregorio , Díaz-Dorronsoro Agnes , Landecho-Acha Manuel , Del Pozo-León José Luís
Published: August 2022

Presentamos el caso de un paciente con endocarditis infecciosa por Candida parapsilosis sobre una zona de sutura vascular en la aorta torácica ascendente. La RM de corazón fue determinante a la hora de establecer un diagnóstico correcto.
Radical cation Diels–Alder reactions of arylidene cycloalkanes
Authors: Nakayama Kaii , Kamiya Hidehiro , Okada Yohei
Published: August 2022

TiO2 photoelectrochemical and electrochemical radical cation Diels–Alder reactions of arylidene cycloalkanes are described, leading to the construction of spiro ring systems. Although the mechanism remains an open question, arylidene cyclobutanes are found to be much more effective in the reaction than other cycloalkanes. Since the reaction is completed with a substoichiometric amount of electricity, a radical cation chain pathway is likely to be involved.
The Effect of Saccharomyces cerevisiae Inoculum Concentration On Bioetanol Production From Cocoa Peel (Theobroma cacao L)
Authors: Hidayah Thauhidayatul
Published: August 2022

This study aims to determine the effect of S. cerevisiae inoculum concentration on the ethanol content produced in the fermentation process of cocoa pods. The study design used a completely randomized design (CRD). Parameters observed were alcohol content, reducing sugar content and pH. The research was carried out in the laboratory scale and pilot scale. The laboratory scale consists of preliminary and major research. Preliminary research aims to find the optimum concentration of H2SO4 to produce the highest reducing sugar. The main research phase, namely hydrolysis using optimum H2SO4 from preliminary research and fermentation using S. cerevisiae inoculum with variations in inoculum concentrations of 0%, 1%, 3%, 5% and 7% (v / v). The aim of The pilot scale is producing bioethanol. Fermentation was carried out for six days at a temperature of 28-300 C, observations carried out every two days. Measurement of alcohol content using the titration method, reducing sugar content by the Somogyi-Nelson method, and the pH measured by the indicator pH. Pilot scale measurements were carried out by distillation and GC-MS test. Average alcohol content, reducing sugar content, and pH were 23.73%, 90.20 µg / ml, and 4.4. From the pilot scale distillation results, 87.6 ml of distillate were obtained from 1L of cocoa pods substrate. GC-MS test results showed that in distillate ethanol contained 74.944%.  The results confirmed  that cocoa pods have the potential as bioethanol raw materials.

Keywords: Bioethanol, Somogyi-Nelson, Saccharomyces cerevisiae, H2SO4
Sistem Informasi Manajemen Kepegawaian Berbasis Web di BPR Kabupaten Lombok Tengah
Authors: Ardhana Valian Yoga Pudya
Published: August 2022

Teknologi dan informasi merupakan dua hal yang tidak dapat dipisahkan pada saat ini. Hal ini terlihat dari proses untuk mendapatkan informasi yang dapat diperoleh secara cepat, tepat, dan akurat dengan didukung oleh kemajuan teknologi yang semakin canggih. Teknologi dan informasi saat ini tidak terlepas dari internet. Dengan adanya internet, penyebaran informasi semakin luas tanpa mengenal waktu dan jarak. Teknologi dan informasi yang menggunakan infrastruktur internet salah satunya adalah website. BPR Kabupaten Lombok Tengah adalah bank yang kepemilikannya dimiliki oleh Pemerintah Provinsi NTB. Dikarenakan BPR ini memiliki 8 (delapan) cabang di Kabupaten Lombok Tengah, kebutuhan adanya sistem kepegawaian secara online sangat mendesak. Untuk itu dirancang sebuah sistem informasi kepegawaian berbasis web di BPR Kabupaten Lombok Tengah. Sehingga, data pegawai dapat diinput dan diolah dimana pun dan kapan pun secara cepat dan menghasilkan data yang akurat.
Sistem Informasi Akuntansi Koperasi Syariah di KSU Tunas Muda Millenium
Authors: Mulyodiputro M. Dermawan , Haeri Refreandi , Yohana Yohana
Published: August 2022

KSU Tunas Muda Milenium sering mengalami kesulitan dalam mengatur administrasi keuangan koperasi menjadi tertib dan rapi. Untuk menyusun laporan keuangan koperasi pengurus koperasi syariah mengalami masalah dan tidak optimal dalam menggunakan aplikasi Microsoft Excel. Pengurus koperasi syariah kerepotan dalam menginputkan data transaksi, kesulitan dalam memantau transaksi tiap harinya. Pengurus koperasi syariah juga mengalami masalah saat menghitung bagi hasil pembiayaan dan simpanan tiap anggota yang harus dihitung satu persatu dengan Microsoft Excel, sedangkan koperasi memiliki anggota yang banyak. Sebagai akibat dari permasalahan tersebut, salah satunya adalah koperasi sering mengalami keterlambatan dalam melaksanakan Rapat Anggota Tahunan (RAT). Metode penelitian dilakukan dengan metode waterfall. Pembangunan sistem informasi akuntansi koperasi syariah dilakukan dengan menggunakan bahasa pemrograman Java dengan metode pemrograman berorientasi objek. Menu-menu yang dihasilkan antara lain: menu data koperasi, menu data awal, menu penerimaan, menu pembayaran, menu memorial dan laporan.
Pengaruh Starter Fermentasi pada Proses Pembuatan VCO
Authors: Hidayah Thauhidayatul , Rosika Herliana
Published: August 2022

Di daerah Lombok, pembuatan Virgin Coconut Oil (VCO) dengan starter ragi masih sangat jarang dilakukan. Mengingat kualitas VCO yang cukup bagus dengan penggunaan starter. Penelitian ini bertujuan untuk mengetahui jenis starter ragi yang mampu menghasilkan produk VCO dengan kualitas terbaik. Jenis Penelitian ini adalah penelitian deksriptif kualitatif, melalui tiga tahapan yaitu tahap persiapan, tahap pelaksanaan (pembuatan santan dan fermentasi krim), dan tahap pengujian. Pada tahap pelaksanaan, krim santan difermentasi menggunakan tiga jenis ragi yaitu ragi tape, ragi tempe, dan ragi roti masing-masing dengan konsentrasi 2% b/v. Hasil Fermentasi kemudian disentrifugasi pada kecepatan 3.000 rpm selama 10 menit, lapisan minyak/VCO yang terpisah dalam tabung kupet kemudian dihitung rendemen, dan dilakukan uji asam lemak bebas dan uji organoleptik. Hasil penelitian menunjukkan rendemen VCO yang berasal dari fermentasi ragi tape memiliki jumlah rendemen yang lebih banyak yaitu 11,17%; fermentasi ragi tempe sebesar 2,13% ; dan fermentasi ragi roti sebesar 0,15%. Kadar asam lemak bebas pada VCO yang diperoleh dengan fermentasi ragi tape sebesar 0,24%; fermentasi ragi tempe sebesar 0,15%; dan fermentasi dengan ragi roti tidak menunjukkan adanya asam lemak bebas. Dengan demikian, kadar asam lemak bebas yang paling baik berasal dari fermentasi ragi tempe (standar nasional kadar lemak bebas pada VCOÂ  maksimum 0,2%). Hasil uji organoleptik menunjukkan bahwa VCO dari fermentasi ragi tempe paling banyak disukai karena memiliki rasa yang paling enak dan aroma yang wangi. Dari hasil penelitian dapat disimpulkan bahwa VCO dari hasil fermentasi ragi tempe paling banyak disukai serta memiliki kadar asam lemak bebas yang paling baik (standar nasional VCO).
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Identifikasi Gugus Hidroksil dan Karbonil dalam Senyawa Organik Pada Tanaman Daun Nanas
Authors: Firmansyah Dodiy
Published: August 2022

Analisa menggunakan FTIR pada tumbuhan daun nanas betujuan untuk mengindentifikasi senyawa organic yang terkandung di dalamnya. Senyawa organik yang penting diidentifikasi dalam tanaman adalah tersebut adalah gugus karbonil dan gugus hidroksil. Identifikasi senyawa organik pada penelitian ini bertujuan untuk (1) mengetahui gugus hidroksil dan karbonil dalam tanaman daun nanas dan (2) mengetahui luas permukaan tumbuhan daun nanas sebelum dan sesudah di cuci menggunakan isopropil alkohol. Identifikasi senyawa organik pada penelitian ini dilakukan dengan 3 tahap yaitu: (1) penumbukakan daun nanasl yaitu penghalusan serat daun nanas, dan pengayakan menggunakan 100 mesh; (2) pencucian menggunakan isopropyl alkohol dari senyawa lain yang terkandung di dalam tanaman daun nanas; (3) analisis hasil identifikasi yang meliputi uji gugus fungsional menggunakan FTIR dan analisa luas permukaan menggunakan SEM. Hasil penelitian menunjukkan bahwa terdapat gugus hidroksil dan karbonil pada masing bilangan gelombang yaitu 3500 cm-1 dan 1700 cm-1.
Perancangan Sistem Informasi Rekam Medis Puskesmas Berbasis UML
Authors: Ardhana Valian Yoga Pudya
Published: August 2022

Saat ini pelayanan kesehatan menjadi prioritas bagi penyedia fasilitas kesehatan. Pelayanan kesehatan dituntut lebih baik lagi sehingga membentuk sistem yang efektif dan efisien. Teknologi sistem informasi sangat diperlukan untuk meningkatkan efektifitas pelayanan kesehatan, sehingga dengan adanya sistem terkomputerisasi dapat memudahkan dalam pengelolaan data dan pengontrolan sistem. Tidak terkecuali di Puskesmas, pelayanan kesehatan sangat diperhatikan mengingat padatnya pasien yang berkunjung ke Puskesmas. Dibutuhkan suatu perancangan sistem informasi agar kinerja Puskesmas dapat lebih meningkat. Oleh karena itu, penulis merancang sistem informasi rekam medis Puskesmas yang berbasis UML, sehingga diharapkan hasil rancangan ini dapat memudahkan petugas Puskesmas dalam menjalankan tugasnya menjadi lebih efektif dan efisien.
Perancangan Aplikasi Keuangan Kampus Berbasis Web
Authors: Ardhana Valian Yoga Pudya , Sapi'i Muh
Published: August 2022

Kehadiran internet di lingkungan kampus, sekolah maupun kantor sudah sangat dibutuhkan mengingat bahwa teknologi informasi ini telah memberikan kemudahan dalam mendukung proses komunikasi dan sarana pra-sarana akan dilakukan. Kebutuhan aplikasi secara online sangat dibutuhkan setiap perguruan tinggi, termasuk aplikasi keuangan. Dengan adanya aplikasi keuangan di perguruan tinggi yang sebelumnya pencatatan data kas masuk dan kas keluar dilakukan secara konvensional, semua nya menjadi lebih cepat dan efisien. Data pembayaran berada dalam satu database sehingga data menjadi valid dan dapat dipertanggungjawabkan.
Karakterisasi Hasil Sintesis Fotokatalis TiO2 Dengan Metode Sol-Gel dan Hidrothermal Untuk Aplikasi Limbah Petroleum
Authors: Manja Manja Nanda Resa , Nasution Hasmalina , Nasihah Zumrotun , Finalia Tengku , Rahmadanis Laila , Prasetya Prasetya , Syafri Rahmadini , Siregar Sri Hilma
Published: August 2022

Petroleum waste (crude oil) has become one of the sources of pollution in the sea. The pollution caused comes from several factors, oil spills from tankers, deliberate disposal of irresponsible industries. The layer of crude oil on the surface of the air holds back gas exchange from the atmosphere and reduces the solubility of oxygen in the waters so that it interferes with the respiration and photosynthesis processes in phytoplankton which are food producers in the sea. This study aims to characterize the synthesized TiO2 photocatalyst material using two methods, namely Sol-Gel (SG) and Hydrothermal (HD) which will then be used for applications in petroleum waste. To determine effectiveness of TiO2 photocatalyst in reducing crude oil spills on the sea surface based on fatty oil parameter tests. The synthesis of TiO2 was carried out by the solgel method (SG) and the hydrothermal method (HD) at various temperatures of 300 oC, 500 oC, and 700 oC. Characterization of the material formed using the SEM-EDX instrument, showed that in general it is spherical in shape, and is composed of C, O and Ti elements. The maximum effectiveness of SG-300, SG-500, and SG-700 was able to reduce fat oil content by 57.19%, 66.14% and 41.42% while HD-300, HD-500, and HD-700 were able to reduce fatty oil content. maximum of 60.87%. , 56.41% and 45.68% in the 120 minute irradiation time. The results showed that the photodegradation process in petroleum waste treatment using TiO2 material was able to reduce the fat oil content.