bluuebunny/crossref_metadata_2025 huggingface dataset:
Split-thickness Skin Grafting in the Management of Cutaneous Sequelae of Intramuscular Pentazocine Injections: A Novel Approach
Authors: Al-Sukhni Layan , Harris Michelle , Rahesh Jasmin , Nazim Muhammad
Published: January 2023

Introduction. Pentazocine, a synthetic opioid with partial agonist and antagonist activity administered by parenteral injection, was used clinically in the 1970s. Dermatologic complications at injection sites were reported soon after its introduction. These complications are thought to be underreported. Many well-documented cases describe the development of fibrosis and calcinosis at the site of parenteral pentazocine injections, but few reports document management or successful treatment of the long-term sequelae of these manifestations. Case Report. The successful use of STSG for the treatment of chronic nonhealing ulcers secondary to pentazocine-induced cutaneous fibrosis in a 78-year-old male is presented. In the early 1970s, he was started on 3-times-daily intramuscular pentazocine injections to treat pain secondary to ulcerative colitis. He injected himself in the proximal thighs and buttocks for a period of approximately 10 years. He gradually developed severe soft tissue calcifications of both buttocks and anterior thighs. In the mid-to-late 1980s, the pentazocine injections were discontinued. The diffuse sclerosis and disfiguring fibrosis remained. Conclusions. This case underscores the lasting effects of pentazocine-induced cutaneous sclerosis and fibrosis, with cutaneous complications manifesting in this patient even decades after use. It also highlights the novel use of STSG as a treatment strategy for these cutaneous complications.
Knowledge, Attitudes and Practices on Antibiotics Use among Cattle Keepers in Nyagatare District, Rwanda
Authors:   Department of Public Health, Mount Kenya University Rwanda, Kigali, Rwanda, JP Mushayija , S Nikwigize ,   Department of Public Health, Mount Kenya University Rwanda, Kigali, Rwanda, C Karangwa ,   Rwanda Food and Drugs Authority, Kigali, Rwanda, R Manishimwe ,   Rwanda Food and Drugs Authority, Kigali, Rwanda, R Habimana ,   Rwanda Food and Drugs Authority, Kigali, Rwanda, E Rutayisire ,   Department of Public Health, Mount Kenya University Rwanda, Kigali, Rwanda
Published: January 2023

The dairy subsector in Rwanda is the most important portion of the livestock sector and antibiotics are frequently used in veterinary aspects to treat zoonotic agents. The present study aimed to determine knowledge, attitudes, and practices on antibiotics use among cattle keepers in Nyagatare District. The target population was 384 cattle keepers and cross sectional study design was conducted. A structured questionnaire was used by researcher to collect the data and SPSS version 21 has been analyzed used to analyze the data. The study findings show that 86.7% were male, 76.0% were married, 85.9% had more than 5 years in keeping cattle, 39.3% had between 11-20 cows in their farms while 34.1% had to make between 1 and 3 kilometers to reach a veterinary pharmacy from their firms. The present study revealed that 64.3% of respondents had a low level of knowledge towards antibiotic use in cattle and 73.7% of the respondents had positive attitude towards antibiotic use in cattle. Cattle keepers who required to walk less than one km from farm to veterinary pharmacy were less likely (AOR=0.06; 95% CI: (0.01-0.30); p=001) to have poor practice on antibiotic use in cattle than those living far from the vet pharmacy. In conclusion, cattle keepers from Nyagatare district demonstrated poor knowledge, positive attitude and poor practices towards antibiotic use. Therefore, educational programs are urgently needed to train to raise famer’s awareness about proper antibiotics use with particular attention to public health problems that may rise due to poor use of antibiotics in cattle.
Neurophysiological Examination of the Effects of Behavioral Antecedents on Physical Balance in Older Individuals
Authors:   Department of Physical Therapy, Kyoto Tachibana University, Japan, T Kodama , T Abiko ,   Department of Physical Therapy, Kyoto Tachibana University, Japan, N Matsuo ,   Department of Physical Therapy, Kyoto Tachibana University, Japan, H Yamaguchi ,   Department of Advanced Development, AISIN Co., Ltd., Japan
Published: January 2023

Falls in older individuals can be caused by balance disorders, influenced by predictive factors based on self-efficacy and outcome expectation. This study investigated the relationship between predictive factors related to regional neural functional activity and postural control. We included 16 older men (average age, 76.4±5.8 years) and evaluated their balancing ability and fall-related selfefficacy using the Japanese version of Mini-Balance Evaluation Systems Test (J-Mini-BESTest) and the Japanese version of the Falls Efficacy Scale (JFES), respectively. We performed an electroencephalogram before, during, and after postural perturbations. The cortical activity in the right Inferior Parietal Lobe (IPL) and Supplementary Motor Area (SMA) was analyzed using current density in the specific regions of interest. Foot Response Values (FRV) were used to evaluate physical responses during postural perturbations. The neural activity values in the IPL after postural perturbations indicated a significant positive correlation with JFES and J-Mini-BESTest scores when prior information was provided to participants. The neural activity values in the SMA before postural perturbations showed a significant positive correlation with J-Mini-BESTest score and a significant negative correlation with FRV. Furthermore, during postural perturbations, subjects with prior information exhibited significant positive neural correlations with neural activity between the SMA and IPL. These results suggest that neural activity in these brain regions influence balancing ability and predictive factors. Prior knowledge of a postural perturbation’s timing could be a compensatory factor promoting the activation of predictive factors.
Risk Assessment System of Fall in the Elderly Using Artificial Intelligence and Cloud Computing
Authors:   Clinical and Experimental Neuroscience (NiCE), University of Murcia, Spain, JD Blasco-García , N Pavón-Pulido ,   Department of Electrical Engineering and Electronic Technology, Technical University of Cartagena, Spain, JA López-Riquelme ,   Department of Electrical Engineering and Electronic Technology, Technical University of Cartagena, Spain, JJ Feliu-Batlle ,   Department of Electrical Engineering and Electronic Technology, Technical University of Cartagena, Spain, R Nieto-Galera ,   AFA Levante. C/ Alameda San Antón, 29. 30205 Cartagena, Spain, MT Herrero ,   Clinical and Experimental Neuroscience (NiCE), University of Murcia, Spain
Published: January 2023

This paper presents a Cloud-based online tool for helping health professionals to predict the risk of falling in the elderly by using the well-known Tinetti’s Test. This tool implements a Deep Learning-based method for allowing several Tinetti scale’s items to be automatically estimated, simply using a conventional camera or a recorded video. From these sources of information, patients’ skeleton is recognized and their movements analyzed by applying some geometric calculations, which provide an objective risk assessment. Results are represented as a set of plots easily interpretable by experts. Several tests, in a controlled environment, have been carried out to validate the accuracy and reliability of the system. Moreover, some tests have been also made with real elderly patients, whose results have been evaluated by therapists. The benefits of using such remote tool for assessing (objective) fall risk, from a usability point of view, are also highlighted.
A STRATEGIC MULTI-STEP REPORPOSING OF ASPIRIN ANTIMICROBIAL ACTIVITY AGAINST RESISTANT SALMONELLA SPP USING PSIDIUM GUAJAVA AND SYZYGIUM AROMATICUM EXTRACTS
Authors: Gideon Mathew , Duniya Emmanuel Kambai , Mamman Abakeyah James , Dennis Samuel
Published: January 2023

For centuries, plant extract has been used for treatments of various diseases, medicinal plants has been a source of many active components of prescribe drugs. Drug resistant Salmonella infections is of growing concern in Nigeria. The aim of this work is this work is to develop a strategy for which acetylsalicylic acid a non-antibiotic can be repurpose to function as an antimicrobial agent by it combination with either Psidium guajava and Syzygium aromaticum extract at lower concentrations of both combining agent that will not be sufficient to inhibit salmonella spp growth individually before combination, to develop a mixture with antimicrobial property that can be able to compete with ciprofloxacin inhibition against Salmonella spp. Eighteen (18) combinations of three drugs (Co-trimoxazole, Tetracycline and Aspirin) each with Syzygium aromaticum (clove) extract and separately again with Psidium quajava (guava) extract in three different stages using concentrated Tetraoxosulphate(vi)acid (H2SO4) and 0.1M sodium hydroxide (NaOH), 31 antimicrobial disk were prepared and tested on salmonella spp. The antimicrobial test at lower concentrations reveals that Scl, a one-step combination of Co-trimoxaazole with clove extract, Ac2, a two-step combination of aspirin and clove extract, Ag2, a two-step combination of Aspirin and guava leave extract were all susceptible to resistant salmonella spp with clear zones of inhibition at 10 µg better than Ciprofloxacin at 20 µg. Aspirin was the best precursor drug which favourably combines with both clove and guava extract to give a carrier product with potential antimicrobial characteristics, this method can also be explored to identify novel compounds, isolates, and purify their active principles for to combat multi-drug resistant bacteria also in antiviral and anticancer research to overcome enormous health challenges.
A Fully Biocatalytic Approach to Angiopterlactone B Based on a Chemoinspired Artificial in Vitro Metabolism
Authors: Kiefer Alexander , Liu Yu-Chang , Gummerer Rebecca , Jäger Christina , Deska Jan
Published: January 2023

Nature's way to construct highly complex molecular entities with virtue as part of biosynthetic pathways is unmatched by any chemical synthesis. Yet, relying on a cascade of native enzymatic transformations to achieve a certain target structure, biosynthesis is also significantly limited in its scope. In this work, non-natural biocatalytic modules are successfully implemented into an artificial metabolism, combining the benefits of traditional retrosynthesis with the elegance and efficacy of biosynthetic networks. In a highly streamlined process, a total synthesis of the tricyclic angiopterlactone B is achieved operating entirely in an aqueous environment while relying on enzymes as reaction mediators.
Comparison of Receptor-Ligand Restraint Schemes for Alchemical Absolute Binding Free Energy Calculations
Authors: Clark Finlay , Robb Graeme , Cole Daniel , Michel Julien
Published: January 2023

Alchemical absolute binding free energy calculations are of increasing interest in drug discovery. These calculations require restraints between the receptor and ligand to restrict their relative positions and, optionally, orientations. Boresch restraints are commonly used, but they must be carefully selected in order to sufficiently restrain the ligand and to avoid inherent instabilities. Applying multiple distance restraints between anchor points in the receptor and ligand provides an alternative framework without inherent instabilities which may provide convergence benefits by more strongly restricting the relative movements of the receptor and ligand. However, there is no simple method to calculate the free energy of releasing these restraints due to the coupling of the internal and external degrees of freedom of the receptor and ligand. Here, a method to rigorously calculate free energies of binding with multiple distance restraints by imposing intramolecular restraints on the anchor points is proposed. Ab- solute binding free energies for the human macrophage migration inhibitory factor - MIF180 system obtained using a variety of Boresch restraints and rigorous and non- rigorous implementations of multiple distance restraints are compared. It is shown that several multiple distance restraints schemes produce estimates in good agreement with Boresch restraints. In contrast, calculations without orientational restraints produce erroneously favourable free energies of binding by up to approximately 4 kcal mol−1. These approaches offer new options for the deployment of alchemical absolute binding free energy calculations.
Point-of-care applicable metabotyping using biofluid-specific electrospun MetaSAMP®s directly amenable to ambient LA-REIMS
Authors: De Spiegeleer Margot , Plekhova Vera , Geltmeyer Jozefien , Schoolaert Ella , Pomian Beata , Singh Varoon , Wijnant Kathleen , Dewindt Kimberly , Paukku Volter , De Loof Alexander , Gies Inge , Michels Nathalie , DeHenauw Stefaan , Degraeve Marilyn , De Clerck Karen , Vanhaecke Lynn
Published: January 2023

In recent years, ambient ionization mass spectrometry (AIMS) including laser ablation rapid evaporation IMS (LA-REIMS), has enabled direct biofluid metabolome analysis. AIMS procedures are however still hampered by both analytical, i.e., matrix effects, and practical, i.e., sample transport stability, drawbacks that impede metabolome coverage. In this study, we aimed at developing biofluid-specific metabolome sampling membranes (MetaSAMP®s) that offer a directly applicable and stabilizing substrate for AIMS. Customized rectal, salivary and urinary MetaSAMP®s consisting of electrospun nanofibrous membranes of blended hydrophilic (polyvinylpyrrolidone and polyacrylonitrile) and lipophilic (polystyrene) polymers supported metabolite ab-, ad-, and desorption. Moreover, MetaSAMP® demonstrated superior metabolome coverage and transport stability compared to crude biofluid analysis and was successfully validated in two pediatric cohorts (MetaBEAse, N=234 and OPERA, N=101). By integrating anthropometric and (patho)physiological with MetaSAMP®-AIMS metabolome data, we obtained significant weight-driven predictions and clinical correlations. In conclusion, MetaSAMP® holds great clinical application potential for on-the-spot metabolic health stratification.
Gestión de riesgo asociado a los niveles de cromo total provenientes del Río Tunjuelo, Bogotá D.C.
Authors: Borda Prada Olga Lucía , Moreno Merchán Andrea Carolina , Guerrero Rodríguez Ariel Fabricio
Published: January 2023

Se presenta aquí un documento relacionado con la gestión sostenible del recurso hídrico, la cual se relaciona con el aprovechamiento, control de calidad y suministro de agua segura a las comunidades. En este sentido, se describen algunos aspectos del objetivo de desarrollo sostenible (ODS) 6 y se presenta una descripción sobre los avances de esta gestión en Colombia. Seguidamente, se presenta un estudio de caso sobre el riesgo asociado a los niveles de cromo en el rio Tunjuelo con el que se logra impactar de manera importante el ODS mencionado. El cromo es una sustancia peligrosa que se transporta en el agua y que puede ser absorbido por los vegetales, de modo que su ingreso en los organismos vivos, no solo a nivel local si no regional, ocurre principalmente a través del recurso hídrico y de los alimentos. Este metal al ingresar a los organismos ya sea por ingestión, contacto o inhalación, genera efectos muy nocivos de orden genético, mutagénico y carcinógeno (Instituto Nacional de salud, 2020). De esta parte, los altos niveles de cromo en los efluentes hídricos y aguas residuales generan patologías importantes en los materiales de construcción. Según la normativa legal vigente, el límite máximo permisible de cromo es de 0,05 ppm de en los residuos líquidos cuando la destinación del recurso es para consumo humano y doméstico, y 0,1 ppm de cromo en los residuos líquidos como valor admisible para la destinación del recurso para uso agrícola y pecuario. En el rio Tunjuelo, se presentan varios vertimientos de cromo, provenientes principalmente de las curtiembres de cuero ubicados en el barrio San Benito, Bogotá, D.C. y según los antecedentes consultados, solo cierto porcentaje de estas empresas cuentan con planta de tratamiento de agua residual. Sin embargo, los procedimientos de estas plantas no son selectivos para el control de este peligroso metal. La problemática mencionada impacta el ámbito social y ambiental debido a que se relaciona con la gestión del recurso hídrico, esto, enmarcado en los objetivos de desarrollo sostenible ODS 3, 6 y 11, que se asocian al impacto de la calidad del agua sobre las personas y sobre el bienestar.
Formulación de lineamientos estratégicos de gestión ambiental para el manejo de los sistemas de agua potable y aguas residuales. Caso: sector urbano del municipio de Ocaña, Norte de Santander
Authors: Arévalo Navarro Luisa , Lozano Lázaro Yeeny , Hermida Castillo Hernando
Published: January 2023

El presente proyecto es un estudio de caso del municipio de Ocaña, Norte de Santander, el cual ha tenido un considerable crecimiento poblacional en los últimos años, quienes han accedido a los recursos hídricos del municipio para diferentes usos, evidenciándose cambios en la calidad del recurso, necesario para el abastecimiento de la población; así como la problemática ecológica y social relacionada con la inadecuada gestión de las aguas residuales generadas. Ante el eventual crecimiento poblacional y la presión que esto ejerce sobre los recursos hídricos; surge la necesidad de establecer lineamientos estratégicos de gestión ambiental para la implementación de prácticas de sostenibilidad en el manejo de los sistemas de agua potable y aguas residuales, en la zona urbana del Municipio de Ocaña - Norte de Santander; a partir de una investigación con enfoque mixto y un alcance descriptivo; desde la descripción del uso del recurso hídrico con base en los lineamientos establecidos en las políticas y la evaluación del nivel de riesgo por abastecimiento de agua, sumado a la percepción de los actores involucrados para conocer la relación de sus constituyentes con los componentes de la política de gestión ambiental urbana; lo que permitió definir estrategias direccionadas a la eficiencia administrativa, optimizando los recursos existentes para el monitoreo, ejecución y cumplimiento de la funciones misionales en el manejo del recurso hídrico; así como la participación comunitaria como actor fundamental en la formulación y aplicación de políticas públicas; y del adecuado manejo y disposición de los vertimientos urbanos en el municipio para su incorporación dentro de los elementos del Sistema de Gestión Ambiental Municipal como aporte a la gobernanza del agua desde el ente territorial.
Tratamiento de agua subterránea para uso doméstico, aplicado a población vulnerable del municipio de Flandes – Tolima. Caso de estudio vereda Puerta Blanca en la IED María Inmaculada año 2022
Authors: Sánchez Caicedo Jorge Alexander , Romero Sanabria Diana Carolina , Barragán Alturo Ancízar , Ospitia Prada Jesús Flaminio , Ospina Zúñiga Óscar Efrén
Published: January 2023

Históricamente la búsqueda de agua potable para consumo humano se ha convertido en todo un desafío para aquellas poblaciones que lo padecen y que año tras año cobra la vida de un sinnúmero de ellas por consecuencia de escases y la baja calidad del vital líquido, situación que no es ajena en la Institución Educativa María Inmaculada (IED), Sede Puerta Blanca del municipio de Flandes-Tolima, ya que no cuentan con un servicio de agua potable apta para consumo y uso doméstico vulnerando un derecho fundamental de la constitución nacional y uno de los objetivos de desarrollo sostenible, establecidos por la ONU, y exponiendo a la población a una posible afectación a la salud, tales como; diarrea, cólera, disentería, fiebre tifoidea, poliomielitis, malnutrición y el dengue. De acuerdo a lo anterior, el objeto principal de la investigación consiste en el diseño y la materialización de un prototipo para el tratamiento de aguas subterráneas, según los parámetros físicos, químicos y microbiológicos de la resolución 2115 del 2007, buscando satisfacer las condiciones de vida de dicha población. El plan metodológico se desarrolla pensando en una población estudiantil de rangos de edad que oscilan de 4 a 12 años, docentes y personas residentes, siendo esta de tipo aplicada, con enfoque de carácter cualitativa y cuantitativa, desarrollado en cuatro fases dando respuesta al objeto de trabajo, identificando las dimensiones sociales, ambientales y económicas, partiendo de una caracterización de la población por medio de encuestas de percepción estructuradas, con la finalidad de obtener información que sustente las condiciones actuales, en segunda instancia se realiza el análisis del estudio de calidad de aguas identificando los agentes contaminantes, posteriormente se evalúa la posible tecnología de tratamiento a implementar; por último el diseño y puesta en marcha del prototipo de tratamiento de aguas considerando los parámetros propuestos y estipulados en la resolución 0330 del 2017, resolución 844 del 2018 y la resolución 799 del 2021 El estudio se proyecta para dar solución a la problemática emergente ya mencionada en la IED María Inmaculada en la vereda de Puerta Blanca del municipio de Flandes en el departamento del Tolima, permitiendo mitigar la concentración de sólidos disueltos, la turbidez, el amonio y eliminar del medio los microorganismo como bacterias, coliformes y Escherichia Coli que afectan la calidad del agua, para que cumpla su función de consumo y uso doméstico con tecnologías que garanticen su proceso de eliminación, transporte y disponibilidad generando un impacto socioeconómico, ambiental y de salud pública positivo para el desarrollo y progreso integral de la comunidad.
Variación de la consistencia del concreto mediante la adición de melaza de caña
Authors: Jaramillo Haidee , Gallardo Amaya Romel Jesús , Martínez Ovallos Ciro Andrey
Published: January 2023

El concreto es uno de los materiales de construcción de mayor demanda debido a sus propiedades y versatilidad, adicionalmente, es común que se empleen diversos aditivos que permiten modificar el comportamiento y la estructura del concreto, potenciando o reduciendo ciertas características que constituyen un beneficio para las obras. Son diversas las investigaciones que se han desarrollado para buscar soluciones alternativas al uso de aditivos a partir de materiales poco convencionales y de menor costo, diversos autores han documentado las bondades del uso de productos derivados del azúcar, logrando potenciar la resistencia y durabilidad del concreto o los morteros. El uso de melaza como superplastificante ha permitido una disminución en la dembanda de agua adicionada en la mezcla para mantener la trabajabilidad, por lo tanto, se reduce la relación agua-cemento efectiva y se mejoran las propiedades del concreto. Además, se ha demostrado que los tiempos de fraguado de las pastas de cemento aumentan con el aumento del contenido de melaza. Resulta evidente que el uso del azúcar y sus derivados son una alternativa viable para mejorar las propiedades del concreto, contribuyendo principalmente a la trabajabilidad de la mezcla y ampliar el tiempo de fraguado. No obstante, en Colombia son pocos los estudios que específicamente analizan la influencia de la melaza proveniente de la caña de azúcar y en mezclas de concreto. Lo anterior ha motivado el desarrollo de esta investigación, en la cual se analizó la incorporación de la melaza en dosificaciones que van desde el 0% al 1%, que, como se ha evidenciado en la literatura, logra mejorar características como la trabajabilidad y ampliación del tiempo de fraguado. Además, constituye una alternativa sostenible, puesto que emplea un material orgánico como lo es la caña de azúcar, la cual hace parte de la producción agrícola en varias regiones del país. Se realizó la incorporación de melaza en mezclas de concreto convencional diseñado con una relación a/c de 0.54 y una consistencia media para asentamientos entre 50 y 100 mm, en dosificaciones de 0.2%, 0.4%, 0.6%, 0.8% y 1.0% respecto a la cantidad de agua. La melaza es de uso comercial con un peso específico de 1.4 g/cm3, un PH de 5.0 y una humedad del 26%. Los resultados obtenidos indican que para las dosificaciones del 0.4% de melaza se logran una consistencia del concreto en términos de asentamientos de hasta 3.2 cm pasados 60 minutos desde el mezclado, valor que supera a la mezcla de control con la cual no se obtuvo ningún valor de asentamiento a los 60 minutos. Adicionalmente, la consistencia del concreto con aditivo comercial respecto al concreto con 1% de melaza tiene una variación porcentual del 20% inmediatamente después del mezclado, lo cual indica, que la melaza de caña alcanza valores cercanos a los obtenidos con plastificantes de uso comercial luego del proceso de mezclado.
Diseño de un gasificador de lecho fijo en equicorriente de núcleo abierto para operar con cascarilla de arroz
Authors: Carmona Agudelo Óscar Mauricio , Díaz Ortiz Sebastián , Garzón Mercado José Reinaldo , Morales Rojas Andrés David , Lenis Yuhan Arley
Published: January 2023

Los problemas medioambientales asociados al uso de combustibles fósiles y la eventual escasez de estos han motivado el desarrollo de tecnologías de aprovechamiento de fuentes renovables de energía. Entre estas, sobresale la biomasa, por su disponibilidad, producción con poca dependencia de las condiciones ambientales y facilidad de conversión. Por otro lado, en Colombia se producen cerca de 520.000 toneladas de cascarilla de arroz anualmente, ubicando este residuo como uno de los de mayor potencial energético. Entre los métodos de aprovechamiento, se destaca la gasificación por generar un gas que puede ser empleado en máquinas térmicas convencionales luego de pocas modificaciones. En Colombia existen muy pocas experiencias documentadas en las que se utilice la gasificación como mecanismo de valoración energética de la biomasa y dada la gran aplicabilidad de esta tecnología, en este proyecto se presenta el diseño y los avances en la construcción de un prototipo de gasificación de lecho fijo equicorriente de núcleo abierto para operar con cascarilla de arroz. Se selecciona como potencia de diseño 20 kWth, debido a que, de usar el gas para generación eléctrica, podría ser empleado en grupos electrógenos de baja potencia, inferior a 5kWe, los cuales son de uso común en zonas con bajo nivel de acceso a la electricidad. El diseño del reactor parte de mediciones experimentales exploratorias realizadas en un gasificador equicorriente invertido, en donde se determinó que la tasa específica de gasificación (SGR) varía entre 120 y 200 kg/h/m2 mientras se produce un gas con poder calorífico inferior (PCI) entre 3.5 y 4 MJ/Nm3, valores que dependen del flujo de gasificante empleado y del estado termoquímico del proceso. Haciendo uso de relaciones termodinámicas y de métodos Heurísticos, se determinan las dimensiones principales del reactor, así como sistemas y subsistemas requeridos para su operación en continuo. De los resultados se destaca que, para la potencia de diseño definida, se requiere de un lecho cilíndrico de sección transversal de diámetro 0.35 m y longitud de 1 m. Las temperaturas alcanzadas en las pruebas exploratorias se mantuvieron por debajo de lo que permite emplear acero inoxidable AISI 304 como material de la zona de reacción. Actualmente la construcción del reactor presenta un grado de avance cercano a 90% y se han iniciado pruebas de verificación de flujo de biomasa en frio.
Obsolescencia programada en la industria del plástico
Authors: Prieto Sanabria Diana María , Alcalá Zárate Luisa Fernanda , González Londoño Andrés Felipe , González Narly
Published: January 2023

La obsolescencia programada es un concepto que se ha utilizado con mayor frecuencia en las últimas décadas, esta definición se relaciona con la vida útil que puede llegar a tener los productos creados por las empresas a fin de definir el tiempo de reducción del rendimiento de cada uno de los productos. Con esto, las empresas buscan encontrar estrategias que se pueden llegar a realizar referente al uso de sus productos en el mercado. En la industria actual esto significa un aspecto positivo, teniendo en cuenta que, si la vida útil de los productos es menor, las ventas de la empresa serán más constantes o crecientes, lo que significara un aumento y un flujo de ingreso continuo; pero para el medio ambiente este concepto es una problemática de gran impacto, ya que se encuentra ligado con el consumo en grandes cantidades y el desecho de manera acelerada de los productos. En el desarrollo de las actividades empresariales uno de los materiales principales para el estudio de la obsolescencia programada es el plástico, este material por sus condiciones físicas y químicas es considerado como un elemento polivalente, debido a que se puede utilizar para diferentes áreas en los sistemas productivos. Acorde con los estudios realizados por el instituto federal suizo de tecnología, se ha podido evidenciar un crecimiento exponencial de la industria de los plásticos debido a su gran utilización en el mercado y a su gran campo de acción por medio de su capacidad de adaptación; sin embargo, el inconveniente de este incremento, es que el plástico al ser una unión de polímeros de difícil descomposición, genera un impacto negativo al medio ambiente. Según estudios, en el año 2015 los plásticos causaron el 4,5% de las emisiones mundiales de gases de efecto invernadero, lo que muestra el gran impacto ecológico y ambiental que puede llegar a tener este material al momento de ser desechado. Es así entonces que este proyecto investigativo, busca entender las causas y consecuencias por las cuales el medio ambiente se ve afectado debido a la producción en masa de las industrias de plásticos en la actualidad; además de la búsqueda de concientización para el desarrollo de proyectos sustentables con el fin de obtener productos plásticos con una vida útil más larga y de una mayor durabilidad, así como la importancia que puede llegar a tener la reutilización de este material.
Los adolescentes y el uso de las redes sociales. Un análisis desde la óptica de la ciencia de datos y el procesamiento de lenguaje natural
Authors: Castillo Landínez Sandra , Caicedo Rodríguez Pablo Eduardo , Mosquera Bolaños Julio Andrés
Published: January 2023

En la actualidad el uso masivo de redes sociales afecta de manera significativa a las comunidades educativas, especialmente a los estudiantes de los grados sexto a once, quienes se encuentran en etapas de la pubertad y la adolescencia, caracterizadas por una búsqueda importante de aceptación y reconocimiento y encuentran en este tipo de medios la forma más indicada para hacerlo. Se estima que la población colombiana que utiliza redes sociales es de aproximadamente 39 millones de personas, según datos del portal We Find You, de estos, el 6.1% son activos en redes sociales y se ubican en el segmento escolar de sexto a grado once de acuerdo con el portal Branch.com; este porcentaje ha sido fuertemente afectado por el aislamiento ocasionado por la pandemia, aumentando su proporción. Este trabajo propone el uso de algoritmos de procesamiento de lenguaje natural para estudiar las respuestas consignadas en un instrumento por parte de los estudiantes de bachillerato del Colegio Los Andes (Popayán), se buscó establecer la polaridad gramatical de sus comentarios para averiguar la afectación de los discentes ante el fenómeno de las redes sociales.
Truthmakers, Incompatibility, and Modality
Authors: Saitta Vita , Plebani Matteo , Rosella Giuliano
Published: January 2023

This paper introduces a new framework, based on the notion of compatibility space, obtained by adding a primitive incompatibility relation to a state space in the sense of Fine. The key idea inspiring the framework is to modify Fine's truthmaker semantics by taking the notion of incompatibility as primitive, and use it to define other notions. We discuss some interesting features of the framework and explore its advantages over the standard framework of state spaces. We review some applications of the framework, including proofs of soundness and completeness theorems for a number of logics, one way to use compatibility states to mirror Kripke frames, and an exploration of a way to use the new framework to provide truthmaking clauses for modal formulas.
Deconstructing dependence and gender concerns in men's hostile sexism
Authors:   , Fisher Molly
Published: January 2023

Hostile sexism describes attitudes characterising women as deliberately attempting to emotionally exploit men and challenge men’s power. Men who endorse hostile sexism often employ negative strategies to reduce any risk of exploitation and feelings of dependence, such as withdrawing from difficult conversations. However, no research has identified whether this occurs due to concerns about depending on women or concerns about depending on others more generally. My thesis tests how men’s endorsement of hostile sexism is associated with experiences of seeking support across different types of support providers (e.g., men vs. women) and contexts of dependence (e.g., romantic partners vs. non-romantic close others). Chapter Two tested support-seeking in heterosexual people across a context of romantic dependence (i.e., relying on a partner; Study 1) and non-romantic dependence (i.e., relying on friends of mixed genders; Study 2). Across both studies, men who endorsed hostile sexism were more resistant to seek support from people they were more dependent on—but there was no evidence that resistance emerged more strongly for relationships with women (vs. men). Chapter Three presents an observational study testing links between people’s endorsement of hostile sexism and their patterns of support behaviour from an unknown person to accomplish a joint task. Results did not reveal any evidence that situational dependence (i.e., not having the resources to complete a task) was associated with expected patterns of support seeking by heterosexual men who endorsed hostile sexism. Instead, men who endorsed hostile sexism were generally resistant to support when paired with other men rather than women. Chapter Four focused on romantic dependence by testing whether heterosexual men who endorsed hostile sexism received less support from their female romantic partners over time. Dyadic analyses indicated that men’s hostile sexism was linked with lower perceptions of partner support and partners’ reports of providing less support. In sum, testing the characteristics of men’s endorsement of hostile sexism by varying the dependence and gender of relationships identifies: (1) that men’s endorsement of hostile sexism is personally costly across a variety of relationships, and (2) that research often focuses on the gendered dynamic of men’s hostile sexism (e.g., fears of exploitation by women) when negativity is more attributable to situations of dependence than gender.
As Tecnologias Digitais de Informação e Comunicação (TDIC) e a relação com o saber no processo de ensino e aprendizagem do Cálculo como objeto de estudo
Authors: Menezes Daniele Costa Fonseca , Charlot Veleida Anahi Capua da Silva , Araujo Enio Gomes
Published: January 2023

Este artigo apresenta um mapeamento sobre estudos realizados acerca do ensino da disciplina de Cálculo I diante do uso das Tecnologias Digitais de Informação e Comunicação (TDIC), integrando uma revisão bibliográfica da pesquisa de Mestrado em Ensino de Ciências e Matemática, desenvolvida na Universidade Federal de Sergipe (UFS). Esta pesquisa tem como foco a relação com o saber de professores e alunos na referida disciplina diante do uso das tecnologias, no Instituto Federal de Educação, Ciência e Tecnologia de Sergipe. Para tanto, tivemos como base os estudos de Charlot (2000; 2005) para compor o corpus desta investigação. O mapeamento possibilitou conhecer o que os estudos revelam sobre como o uso das tecnologias no ensino de Cálculo I — e/ou tendo como base a teoria da relação com o saber — tem sido abordado pela comunidade cientifica da Educação Matemática ou do Ensino de Ciências e Matemática.
Migration of the Chinese to the Urals: Characterization of Archival Sources of the 20th-21st Centuries
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Avdashkin Andrey A.
Published: January 2023

In the article, the author examines documents from the State Archive of the Russian Federation, United State Archive of the Chelyabinsk Region, State Archive of the Perm Krai, and State Archive of the Sverdlovsk Region concerning migration from China to the Urals in the 20th-21st centuries. This chronological period covers the main milestones of the Chinese stay in Russia, and in the Urals on particular. In order to conduct historical research on the topic of Chinese migration within the territorial framework of the Urals, it is necessary to generalize these sources, to assess their potential and cognitive limitations. The most significant array of archival documents dates back to the early 20th century. It was during the First World War that severe labor shortage forced Russian officials to approve engaging workers from China to fulfill a large-scale defense order. Thus, a rather voluminous layer of documentation for 1915–17 was formed at the local level, characterizing the practice of recruiting the Chinese to the Ural factories, mines, and logging, the features of their life, and specifics of their social organization. Working with these documents allows the researcher to get a full picture of placement and use of the “yellow” labour in the Urals before the revolution. The available archival files indicate that the efficiency of the Chinese often left much to be desired, but their large numbers, low cost of transportation and maintenance were an undoubted advantage. Some archival fonds of the Soviet authorities give an idea of the socio-demographic composition of the Chinese who remained to live in the USSR in the 1920s-1930s. The next voluminous collection of documents on the topic was formed during the years of the Soviet-Chinese friendship in the 1950s. During these years, the Chinese took a significant part in the construction of industrial enterprises and infrastructure facilities. In the Urals, the Chinese concentrated mainly on the construction of the Molotovstroy facilities. The last layer of archival data dates back to the post-Soviet period and does not seem as informative as the fonds deposited in the late imperial and Soviet periods. To date, relatively few sources have been found in the archives to characterize the migration from the PRC to Russia after the collapse of the USSR. The most reliable data from archival documents permit to trace the number of the Chinese labor migrants in Russia in the first two decades of the 21st century and to establish the main areas of their concentration in the Urals and other regions of the country.
NEUROLINGUISTIC PROGRAMMING IN SPORTS
Authors: Rohach Oksana , Wisecup Daniel
Published: January 2023

In this article, we examine the literature presented on the use of neurolinguistic programming (NLP) in the world of sports.  The techniques have been applied with success in a number of occasions at different skill levels to improve performance.  NLP operates on the principle that human beings have the capacity to set and achieve their goals, and gives a framework in which these objectives can be attained.  These principles have been observed in both a theoretical and practical way in relation to sports.  In the first part of the article, we review the theoretical literature on the topic. From a theoretical standpoint, scholars have asserted that the perception of reality through the senses plays an important role, and this perception can be influenced by the language we use.  Clear communication in teaching is vital for training athletes to reach their potential.  In the second part, we look at applications of NLP in different spheres of sports and the way it is applied to real athletes with certain obstacles hindering their progress.  We attempt to summarize this literature and present a potential path for future research.  There have been criticisms of NLP, so it is important to consider them in an unbiased way, giving thought to what can be done in the future to give answer to them.
Comparative Study of Improvement of Hematite as Visible Light-Driven Photocatalyst by Doping with Zinc and Copper
Authors: ALP Emre
Published: January 2023

The low cost, earth abundance, nontoxic, and efficient photocatalysts materials have a critical role in order to solve environmental issues. In this regard, hematite (α-Fe2O3) has received significant attention due to its desirable properties. In the present study, zinc-doped and copper-doped hematite nanoparticles were synthesized by the hydrothermal method. The photocatalytic features of produced nanopowders were investigated. The evaluations of photocatalytic activities of synthesized nanoparticles were executed by monitoring the degradation rate of Rhodamine B (RhB) under the solar simulator in heterogeneous photocatalysis. Compared to commercial Degussa TiO2 powder, the transition metal doped hematite (α-Fe2O3) samples showed better photocatalytic activities against RhB under the solar simulator. It was observed that even though there were no significant differences in their characteristic properties strongly affecting photocatalytic activity such as morphological features, optical absorption characteristics, and band gaps, Cu-doped α-Fe2O3 nanoparticles exhibited higher photocatalytic activity, which is %20 higher than the Zn-doped α-Fe2O3. The synthesized Cu-doped hematite nanoparticles are hopeful materials as a visible-light-driven photocatalytic material to degrade organic pollutants in aquatic media.
NECESSIDADE E URGÊNCIA DE REVISÃO DA REGULAMENTAÇÃO BRASILEIRA SOBRE DENTIFRÍCIOS FLUORETADOS, E POSICIONAMENTO DA ACADEMIA BRASILEIRA DE ODONTOLOGIA
Authors: Caldarelli Pablo Guilherme , Pinheiro Liana Lima , Cury Jaime Aparecido
Published: January 2023

Introdução: a primeira regulamentação sobre dentifrícios fluoretados do Brasil (Portaria no 22, de 20/12/1989, da ex-Secretaria Nacional de Vigilância Sanitária) estabelecia não só a concentração máxima de fluoreto total (1500 ppm F) que um dentifrício deveria conter em termos de segurança de produto de higiene, como a mínima de fluoreto quimicamente solúvel (potencialmente ativo contra cárie) para garantir o benefício anticárie da escovação dental. Objetivo: demonstrar a necessidade e urgência de revisão da vigente regulamentação brasileira sobre
dentifrícios fluoretados e registrar o posicionamento da Academia Brasileira de Odontologia. Fonte de Dados: Lilacs, PubMed, SciELO e nos arquivos do
laboratório de Bioquímica Oral da FOP-UNICAMP. Síntese dos Dados: desde 1994, a Portaria nº 22 sofreu contínuas modificações culminando com a resolução ANVISA RDC No 530 de 04/08/2021. As mudanças feitas não foram baseadas no
conhecimento científico mundial, do qual a Odontologia brasileira é referência. Assim, desde a primeira mudança feita em 1994, não mais foi dada importância à qualidade do fluoreto de um dentifrício, priorizando apenas a quantidade máxima
de fluoreto total que ele deveria conter. Dezenas de publicações científicas tem sido feitas alertando para esse erro histórico, mas até o momento se mostraram
infrutíferas. Trata-se de problema de saúde pública, pois em acréscimo tem afetado a população mais vulnerável à cárie dentária. Conclusão: a necessidade e urgência da revisão da resolução ANVISA nº 530, requer ação da sociedade como um todo, razão desta revisão e posicionamento formal circunstanciado da Academia Brasileira de Odontologia (AcBO).
Implementasi Algoritma K-Means dalam Analisis Klasterisasi Penyebaran Penyakit Hiv/Aids
Authors:   Universitas Buana Perjuangan Karawang, Sari Tita Puspita , Hananto April Lia ,   Universitas Buana Perjuangan Karawang, Novalia Elfina ,   Universitas Buana Perjuangan Karawang, Tukino Tukino ,   Universitas Buana Perjuangan Karawang, Hilabi Shofa Shofia ,   Universitas Buana Perjuangan Karawang
Published: January 2023

The most crucial component of everyone's life is their health, especially for young people, health problems that often arise in the younger generation are promiscuity or free sex. HIV/AIDS cases were reported in the last 30 years, from 1992 to 2022 as many as 2,052 were infected with HIV/AIDS. Dozens of them are students and college students. This study's objective was to cluster the total cases of HIV/AIDS based on sub-districts in Karawang district. Seeing which areas need more attention in dealing with cases of HIV/AIDS transmission and the areas with the highest cases can serve as a manual for choosing the highest areas and these areas can be the main focus. The approach adopted for this study is data mining. To solve the existing problems, the authors use the K-Means algorithm using 4 clusters to find out which sub-district groups have very high, high, medium and low numbers of HIV/AIDS cases by calcualating the centroid/mean of the cluster data. The results of the study contained 4 clusters as follows: cluster 0 with low criteria earned 73%, cluster 1 with very high criteria earned 3%, cluster 2 with medium criteria earned 7%, and cluster 3 with high criteria earned 17%
Sistem Informasi Pelayanan Penerimaan Jasa Tenaga Kerja Berbasis Web (Studi Kasus PT. Defita Bersaudara)
Authors:   Universitas Hamzanwadi, Wasil Muhammad , Mahpuz Mahpuz ,   Universitas Hamzanwadi, Candra Permana Baiq. Andriska ,   Universitas Hamzanwadi, Putra Yupi Kuspandi ,   Universitas Hamzanwadi
Published: January 2023

Technology in this era is developing very rapidly. Especially in the business sector, many companies or agencies use information technology as a means of promotion and information in developing business opportunities, one of which is PT. Defita Bersaudara is a service distribution company engaged in the field of employment abroad. This company distributes Indonesian Migrant Workers Services to several countries such as Malaysia, Singapore, Hong Kong and Taiwan. The system that runs on PT. Defita Bersaudara still uses excel-based data processing in managing and collecting all data on Indonesian workers who depart through PT. defita brothers. This results in the same data being input repeatedly. This information system is capable of providing web-based employment services to make it easier for workers to find information and apply for jobs, applicants do not have to come to the company to register as prospective workers. This application uses the CodeIgniter Framework, so that it can be accessed through internet media by related parties, both the company itself and the wider community in general.
PEMANFAATAN GRUP WHATSAPP SEBAGAI MEDIA PEMBELAJARAN ONLINE DI SMPTRI SUKSES KOTA JAMBI
Authors: Dian Pertiwi Ria , Hasanah Dewi , Trimadona Eliza , Oktarina Yulia
Published: January 2023

Penelitian ini membahas tentang pemanfaatan grup WhatsApp sebagai media pembelajaran online Di Sekolah Menengah Pertama Tri Sukses Boarding School Kota Jambi. Tujuan penelitian ini untuk mengetahui (1) Aspek-aspek yang ada dalam pemanfaatan grup WhatsApp Sebagai media pembelajaran online, (2) Hambatan dalam pemanfaatan grup WhatsApp sebagai media pembelajaran online. Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan teknik pengumpulan data berupa observasi, wawancara dan dokumentasi. Teknik analisis data berupa data reduction, data display dan conclution drawing/verification. Hasil penelitian ini menunjukkan bahwa guru telah memanfaatkan grup WhatsApp. Aspek-aspek yang ada dalam pemanfaatan grup whatsapp sebagai media pembelajaran online aspek kognitif, afektif, dan psikomotorik dalam bentuk penugasan dan menyesuaikan dengan fitur yang ada dalam aplikasi WhatsApp fitur chat (pesan teks), panggilan suara, dokumen, foto, video, voice note. Adapun kendala dalam penerapan pemanfaatan grupWhatsApp seperti terkendalanya sinyal, terbatasnya kuota, tugas yang menumpuk, Tidak memiliki handphone, dan kesulitan dalam memahami materi yang diberikan.