bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSISTÊNCIA DE ENFERMAGEM NA PREVENÇÃO DE LESÕES POR PRESSÃO NA UNIDADE DE TERAPIA INTENSIVA
Authors: Rodrigues Ana Karoline da Silva , Miranda Dalila Campos , Batista Emily Andrade , Silva Odegilson Ciqueira da , Nogueira Ronierison Nunes , Silva Keila Bezerra da
Published: June 2024

Introdução: A Lesão por Pressão (LPP) é uma das complicações encontradas na UTI devido ao período de internação, a restrição no leito e a condição de saúde dos pacientes. Esses indivíduos estão suscetíveis a desenvolver esse tipo de lesão, que pode refletir de forma negativa na qualidade da assistência de enfermagem prestada. Objetivo: Descrever quais intervenções utilizadas para a prevenção de Lesão por Pressão na Unidade de Terapia Intensiva que se destacam na literatura cientifica. Metodologia: O presente estudo utilizou o método de Revisão Integrativa da Literatura utilizando artigos científicos indexados em bancos de dados de pesquisa eletrônica nos últimos cinco anos (2019-2024). Resultados e Discussão: Foram encontrados ao todo 470 artigos Ao adicionar os critérios de inclusão e exclusão, o quantitativo reduziu-se para 36 artigos e com a leitura e análise minuciosa dos artigos, o número reduziu-se a 10. A ocorrência da LPP esta associada a falhas do cuidado da equipe de enfermagem e a fatores intrínsecos do paciente que pode favorecer ao desenvolvimento da lesão. A principal estratégia para combater as LPP é a identificação dos fatores de riscos associado aos pacientes no processo de formação das lesões. É importante que o profissional detenha o conhecimento suficiente para reconhecer precocemente esses riscos. Conclusão: Com a revisão dos estudos selecionados, foi possível identificar a importância do enfermeiro nos cuidados preventivos na UTI e a relevância da avaliação individual, uso de dispositivos e materiais adicionais, reposicionamento, uso de protocolos e escalas para prevenir e/ou tratar as lesões Tais ações são imprescindíveis e encontram-se respaldado na literatura cientifica para melhorar os cuidados de enfermagem ao paciente internado na UTI.
RELACIONES MÉDICO-PACIENTE EN TELEMEDICINA: REVISIÓN INTEGRADORA DE LA LITERATURA
Authors: Meneses Rafael Martins de , Lima Éfren Paulo Porfírio de Sá
Published: June 2024

La Telemedicina surge de los cambios de paradigma provocados por la tecnología (Faleiros Junior; et al, 2020; Rocha; et al, 2020), impactando en la Medicina y el Derecho. Así, el objetivo general de este estudio es analizar las consecuencias socio-jurídicas de las relaciones médico-paciente en Telemedicina, a partir de una investigación del régimen jurídico de la materia y sus repercusiones teóricas y prácticas. La metodología utilizada fue una revisión bibliográfica combinada con una revisión integradora de la literatura. La bibliografía especializada se seleccionó siguiendo los siguientes criterios de inclusión: trabajos libres completos, publicados a partir de 2015 e investigaciones relacionadas con los objetivos del estudio. Los criterios de exclusión fueron: trabajos que no fueran artículos científicos o incompletos; que no fueran gratuitos; publicaciones anteriores a 2015; investigaciones con no humanos o in vitro; y trabajos fuera de tema. Así, esta investigación visibiliza las debilidades de la Telemedicina, en la medida en que indica cuáles son las lagunas normativas y estructurales que aún impiden la plena implantación de esta modalidad asistencial a distancia. Son necesarios cambios estructurales en la forma de relacionarnos con las exigencias de la implantación de la Telemedicina, con la difusión de medidas exitosas y la minimización de daños, teniendo en cuenta las realidades relatadas por pacientes y profesionales médicos. Hacer más visibles los debates científicos sobre este fenómeno podría cambiar estos impasses (bio)legales.
PROJETO DE UMA CADEIRAS DE RODAS MODULAR
Authors: Costa Ana Helena Perez , Henriques Antonio Manoel Dias
Published: June 2024

Este trabalho teve como objetivo o projeto de uma cadeira de rodas modular com dimensões ajustáveis. A motivação surgiu a partir da constatação da dificuldade de crianças de baixa renda terem cadeiras de rodas adequadas ao seu tamanho durante toda a infância, assim acabam recebendo cadeiras muito grandes ou se tornam maiores que a cadeira em um curto espaço de tempo. Dessa forma, as crianças estão propensas a diversos problemas de saúde causados por uma cadeira inapropriada. Portanto, a partir de um estudo histórico do desenvolvimento da cadeira de rodas e das soluções já existentes para problemas similares, as alternativas de resolução do problema foram levantadas. Em seguida, um estudo ergonômico da adaptação da cadeira de rodas ao corpo humano foi realizado, além da consulta à potenciais usuários para a definição da configuração mais adequada à situação. Definiu-se, então, a configuração final como uma cadeira de rodas com 4 rodas, estrutura rígida e com propulsão manual realizada por meio de aro propulsor. Em seguida, foi realizado o dimensionamento estático de toda a estrutura utilizando-se do software Ansys para simulações e verificação estrutural baseada em forças de ensaios propostos pela ABNT NBR ISO 7176:8 (ABNT, 2009b) conjuntamente com um estudo dos materiais a serem utilizados na confecção da cadeira de rodas, buscando a solução mais barata e leve. Finalmente, obtéve-se a estrutura de uma cadeira de rodas com ajuste de dimensões por meio de tubos concêntricos com tubos externos em PVC e barras internas em alumínio.
Factors Influencing the Incidence of Stunting in Children Aged 24-59 Months in the Work Area Muara Delang Health Center, Jambi
Authors: Cahyaningrum Nadya Elsa , Mars Siwi Pramatama , Suratman
Published: June 2024

Stunting can be caused by many factors such as socio-economics, exclusive breastfeeding, parenting patterns, timing of giving MP-ASI, history of infectious diseases, environmental sanitation, and the role of community leaders. The many factors that influence the occurrence of stunting mean that one of the efforts that can be made to reduce the prevalence of stunting is to identify the factors that influence the occurrence of stunting. This study aims to determine the factors that influence the occurrence of stunting in toddlers aged 24-59 months. This research is a case control study of 75 stunted toddlers and 75 control toddlers aged 24-59 months in the Muara Delang Community Health Center working area for the period February 2023. Independent variables include family income, mother's education level, parenting style, exposure to information, exclusive breastfeeding, history of infectious diseases, dental health, the role of health cadres and the role of community leaders; while the strongest variable in this study was the incidence of stunting. The instrument used in data collection is a questionnaire, then the data will be processed using regression test data analysis. The results of the study show that the factors that influence the incidence of stunting in the Muara Delang Community Health Center work area are parenting style (p=0.049 and B=1.557), exclusive breastfeeding (p=0.005 and B=1.300), dental health (p=0.048 and B = 0.764) and family income (p=0.049 and B=0.763). Parenting style is the most influential factor in the occurrence of stunting in the Muara Delang Community Health Center working area.
Post Stroke Care Education on Knowledge and Skills in Carrying out ROM Using Audio Visual Media
Authors: Rondonuwu Rolly H. S. , Pesak Ellen , Massie Timothy Ch , Sarimin Dorce Sisfiani
Published: June 2024

Stroke is the second leading cause of death and the third leading cause of disability. One in four people is at risk of stroke, there are more than 12.2 million new strokes every year. stroke in Indonesia was 10.9%, and in North Sulawesi province it was 14.2%, and the intervention used in this study was Range of motion (ROM). This research aims to determine the influence of post-stroke care education on the knowledge and range of motion skills of the Silian village community using audio-visual media. This research method is quantitative, with a pre-experimental one-group pre-test and post-test design. The 30 sample respondents used the Random Sampling Technique. The treatment was carried out with Post Stroke Care Education using audio-visual media, exercises were carried out in 30 minutes for 3 days. Skill observation sheet instruments and questionnaires regarding Stroke and ROM using the Paired T-test. The research conducted had significant results where sesewanua was more effective than water with a P value of 0.002. The data results mean that the pretest knowledge is 6.90 and the post-test is 15.50, the average increase in knowledge is 7.93. The pretest skills score is 0.00 and the posttest is 23.43. Further tests using the Paired T-test showed that there was a significant effect of post-stroke care education on a range of motion knowledge (P value 0.00; α 0.05) and there was a significant effect of post-stroke care education on a range of motion skills (P value 0.00; α 0.05). The conclusion is that post-stroke care education increases respondents' knowledge and skills regarding range of motion.
Expression levels of KATP channel subunits and morphological changes in the mouse liver after exposure to radiation
Authors: Zhou Ming , Li Tao-Sheng , Abe Hiroshi , Akashi Hideo , Suzuki Ryoji , Bando Yoshio
Published: June 2024

BACKGROUND

ATP sensitive K+ (KATP) channels are ubiquitously distributed in various of cells and tissues, including the liver. They play a role in the pathogenesis of myocardial and liver ischemia.

AIM

To evaluate the radiation-induced changes in the expression of KATP channel subunits in the mouse liver to understand the potential role of KATP channels in radiation injury.

METHODS

Adult C57BL/6 mice were randomly exposed to γ-rays at 0 Gy (control, n = 3), 0.2 Gy (n = 6), 1 Gy (n = 6), or 5 Gy (n = 6). The livers were removed 3 and 24 h after radiation exposure. Hematoxylin and eosin staining was used for morphological observation; immunohistochemical staining was applied to determine the expression of KATP channel subunits in the liver tissue.

RESULTS

Compared with the control group, the livers exposed to 0.2 Gy γ-ray showed an initial increase in the expression of Kir6.1 at 3 h, followed by recovery at 24 h after exposure. Exposure to a high dose of 5.0 Gy resulted in decreased expression of Kir6.1 and increased expression of SUR2B at 24 h. However, the expression of Kir6.2, SUR1, or SUR2A had no remarkable changes at 3 and 24 h after exposure to any of these doses.

CONCLUSION

The expression levels of Kir6.1 and SUR2B in mouse liver changed differently in response to different radiation doses, suggesting a potential role for them in radiation-induced liver injury.
Sodium-glucose cotransporter-2 inhibitors protect tissues via cellular and mitochondrial pathways: Experimental and clinical evidence
Authors: Sanz Raúl Lelio , García Menéndez Sebastián , Inserra Felipe , Ferder Leon , Manucha Walter
Published: June 2024

Mitochondrial dysfunction is a key driver of cardiovascular disease (CVD) in metabolic syndrome and diabetes. This dysfunction promotes the production of reactive oxygen species (ROS), which cause oxidative stress and inflammation. Angiotensin II, the main mediator of the renin-angiotensin-aldosterone system, also contributes to CVD by promoting ROS production. Reduced activity of sirtuins (SIRTs), a family of proteins that regulate cellular metabolism, also worsens oxidative stress. Reduction of energy production by mitochondria is a common feature of all metabolic disorders. High SIRT levels and 5’ adenosine monophosphate-activated protein kinase signaling stimulate hypoxia-inducible factor 1 beta, which promotes ketosis. Ketosis, in turn, increases autophagy and mitophagy, processes that clear cells of debris and protect against damage. Sodium-glucose cotransporter-2 inhibitors (SGLT2i), a class of drugs used to treat type 2 diabetes, have a beneficial effect on these mechanisms. Randomized clinical trials have shown that SGLT2i improves cardiac function and reduces the rate of cardiovascular and renal events. SGLT2i also increase mitochondrial efficiency, reduce oxidative stress and inflammation, and strengthen tissues. These findings suggest that SGLT2i hold great potential for the treatment of CVD. Furthermore, they are proposed as anti-aging drugs; however, rigorous research is needed to validate these preliminary findings.
Expanding the liver donor pool worldwide with hepatitis C infected livers, is it the time?
Authors: Hashem Mai , Medhat Mohammed A , Abdeltawab Doaa , Makhlouf Nahed A
Published: June 2024

Liver transplantation (LT) provides a life-saving option for cirrhotic patients with complications and hepatocellular carcinoma. Despite the increasing number of liver transplants performed each year, the number of LT candidates on the waitlist remains unchanged due to an imbalance between donor organ supply and the demand which increases the waitlist time and mortality. Living donor liver transplant had a great role in increasing the donor pool and shortened waitlist time for LT candidates. Nevertheless, further strategies can be implemented to increase the pool of potential donors in deceased donor LT, such as reducing the rate of organ discards. Utilizing hepatitis C virus (HCV) seropositive liver grafts is one of the expanded donor organ criteria. A yearly increase of hundreds of transplants is anticipated as a result of maximizing the utilization of HCV-positive organs for HCV-negative recipients. Direct-acting antiviral therapy's efficacy has revolutionized the treatment of HCV infection and the use of HCV-seropositive donors in transplantation. The American Society of Transplantation advises against performing transplants from HCV-infected liver donors (D+) into HCV-negative recipient (R-) unless under Institutional Review Board-approved study rules and with full informed consent of the knowledge gaps associated with such transplants. Proper selection of patients to be transplanted with HCV-infected grafts and confirming their access to direct-acting antivirals if needed is important. National and international consensuses are needed to regulate this process to ensure the maximum benefit and the least adverse events.
Frequency of and reasons behind non-listing in adult patients referred for liver transplantation: Results from a retrospective study
Authors: Biolato Marco , Miele Luca , Marrone Giuseppe , Tarli Claudia , Liguori Antonio , Calia Rosaria , Addolorato Giovanni , Agnes Salvatore , Gasbarrini Antonio , Pompili Maurizio , Grieco Antonio
Published: June 2024

BACKGROUND

Few studies have evaluated the frequency of and the reasons behind the refusal of listing liver transplantation candidates.

AIM

To assess the ineligibility rate for liver transplantation and its motivations.

METHODS

A single-center retrospective study was conducted on adult patients which entailed a formal multidisciplinary assessment for liver transplantation eligibility. The predictors for listing were evaluated using multivariable logistic regression.

RESULTS

In our center, 314 patients underwent multidisciplinary work-up before liver transplantation enlisting over a three-year period. The most frequent reasons for transplant evaluation were decompensated cirrhosis (51.6%) and hepatocellular carcinoma (35.7%). The non-listing rate was 53.8% and the transplant rate was 34.4% for the whole cohort. Two hundred and five motivations for ineligibility were collected. The most common contraindications were psychological (9.3%), cardiovascular (6.8%), and surgical (5.9%). Inappropriate or premature referral accounted for 76 (37.1%) cases. On multivariable analysis, a referral from another hospital (OR: 2.113; 95%CI: 1.259–3.548) served as an independent predictor of non-listing.

CONCLUSION

A non-listing decision occurred in half of our cohort and was based on an inappropriate or premature referral in one case out of three. The referral from another hospital was taken as a strong predictor of non-listing.
Critical considerations for the management of acute abdomen in transplant patients
Authors: Pavlidis Efstathios T , Katsanos Georgios , Kofinas Athanasios , Tsoulfas Georgios , Galanis Ioannis N , Pavlidis Theodoros E
Published: June 2024

The number of solid organ transplantations performed annually is increasing and are increasing in the following order: Kidney, liver, heart, lung, pancreas, small bowel, and uterine transplants. However, the outcomes of transplants are improving (organ survival > 90% after the 1st year). Therefore, there is a high probability that a general surgeon will be faced with the management of a transplant patient with acute abdomen. Surgical problems in immunocompromised patients may not only include graft-related problems but also nongraft-related problems. The perioperative regulation of immunosuppression, the treatment of accompanying problems of immunosuppression, the administration of cortisol and, above all, the realization of a rapidly deteriorating situation and the accurate evaluation and interpretation of clinical manifestations are particularly important in these patients. The perioperative assessment and preparation includes evaluation of the patient’s cardiovascular system and determining if the patient has hypertension or suppression of the hypothalamic-pituitary-adrenal axis, or if the patient has had any coagulation mechanism abnormalities or thromboembolic episodes. Immunosuppression in transplant patients is associated with the use of calcineurin inhibitors, corticosteroids, and antiproliferation agents. Many times, the clinical picture is atypical, resulting in delays in diagnosis and treatment and leading to increased morbidity and mortality. Multidetector computed tomography is of utmost importance for early diagnosis and management. Transplant recipients are prone to infections, especially specific infections caused by cytomegalovirus and Clostridium difficile , and they are predisposed to intraoperative or postoperative complications that require great care and vigilance. It is necessary to follow evidence-based therapeutic protocols. Thus, it is required that the clinician choose the correct therapeutic plan for the patient (conservative, emergency open surgery or minimally invasive surgery, including laparoscopic or even robotic surgery).
Whole-eye transplantation: Current challenges and future perspectives
Authors: Scarabosio Anna , Surico Pier Luigi , Tereshenko Vlad , Singh Rohan Bir , Salati Carlo , Spadea Leopoldo , Caputo Glenda , Parodi Pier Camillo , Gagliano Caterina , Winograd Jonathan M , Zeppieri Marco
Published: June 2024

Whole-eye transplantation emerges as a frontier in ophthalmology, promising a transformative approach to irreversible blindness. Despite advancements, formidable challenges persist. Preservation of donor eye viability post-enucleation necessitates meticulous surgical techniques to optimize retinal integrity and ganglion cell survival. Overcoming the inhibitory milieu of the central nervous system for successful optic nerve regeneration remains elusive, prompting the exploration of neurotrophic support and immunomodulatory interventions. Immunological tolerance, paramount for graft acceptance, confronts the distinctive immunogenicity of ocular tissues, driving research into targeted immunosuppression strategies. Ethical and legal considerations underscore the necessity for stringent standards and ethical frameworks. Interdisciplinary collaboration and ongoing research endeavors are imperative to navigate these complexities. Biomaterials, stem cell therapies, and precision immunomodulation represent promising avenues in this pursuit. Ultimately, the aim of this review is to critically assess the current landscape of whole-eye transplantation, elucidating the challenges and advancements while delineating future directions for research and clinical practice. Through concerted efforts, whole-eye transplantation stands to revolutionize ophthalmic care, offering hope for restored vision and enhanced quality of life for those afflicted with blindness.
QR WITH BLOCKCHAIN BASED COUNTERFIET PRODUCT IDENTIFICATION
Authors:   Department of Computer Science and Engineering, Professor, Dhanalakshmi Srinivasan Engineering College, Perambalur
Published: June 2024

Product tracking using blockchain technology involves creating a tamper-proof and immutable record of a product's journey from its creation to its delivery. This can be achieved by creating a digital ledger that records every step of the product's journey, from its origins to the point of sale. Using blockchain technology for product tracking can provide a number of benefits, including increased transparency and accountability, reduced fraud, and improved efficiency. The use of blockchain technology can help prevent the production and distribution of counterfeit products by creating a secure and transparent supply chain. One of the key features of blockchain technology is its ability to create a decentralized ledger of all transactions that occur within a given network. Each transaction is verified by a network of nodes, making it nearly impossible to tamper with or manipulate the data stored on the blockchain. By using blockchain technology, manufacturers and distributors can track every step in the supply chain, from the sourcing of raw materials to the delivery of finished products to consumers. This can help ensure that every product is authentic and has not been altered or replaced with a counterfeit. In this application provides a blockchain-based solution for combating counterfeit products is the use of unique digital identities, or "cryptographic hashes," for each product. These hashes are recorded on the blockchain, allowing anyone to verify the authenticity of a product by scanning its barcode or QR code. The digital identity can also include information about the product's origin, manufacturing history, and other relevant details.
Pengaruh Penggunaan Media Aplikasi Perplexsity Berbasis AI Terhadap Keterampilan Menulis Teks Eksplanasi Siswa-Siswi Smp Kelas Vlll
Authors: Situmorang Hot Ria , Siagian Beslina Afriani , S Monalisa Frince
Published: June 2024

This research aims to determine the effect of using AI-based Perplexsity application media on the explanatory text writing skills of class VIII students at SMP N 18 Medan. This type of research is Quantitative Experimental Research with a One group Pretest and Posttest design research design. The population in this study was all class VIII students with a total of 30 students determined using cluster sampling technique. The data analysis techniques used are Normality test, Homogeneity test and Hypothesis test. After conducting research for pretest and posttest experiments using AI-based perplexity application media, the average pretest score was 45.55 and the posttest class was 80.00. The pre-test and post-test data prerequisite test results stated that the sample was normally and homogeneously distributed. From the results of hypothesis testing in this research, a "t" test was carried out at a significant level of 5%, namely dk = N1+N2, dk =30+30- 2 = 58. From df 58, a significant level of 5% = 1.667 Ttable was obtained. From the results of the calculations carried out, it can be seen that Tcount > Ttable 12.0859 > 1.667. So the null hypothesis (Ho) is rejected and the hypothesis (Ha) is accepted. Thus, it can be stated that the ability to write explanatory text is influential using AI-based perplexity application media.
Sosyal Medya Pazarlamasında Yapay Zekâ Teknolojilerinin Tüketim Alışkanlıkları Üzerindeki Rolü: Kuşaklar Arası Bir İnceleme
Authors: Özkök Şişman Özge , Temelli Coşgun Asena
Published: June 2024

Günümüzde yapay zekâ temelli uygulamaların sosyal medya pazarlamasında hızla önem kazanması, marka ve reklamverenlerin de dikkatini çekmiştir. Bu doğrultuda sosyal medya pazarlaması ve yapay zekâ temelli uygulamalarının, kullanıcıların tüketim motivasyonları üzerinde nasıl bir rol üstlendiği önemli bir araştırma konusu olarak karşımıza çıkmaktadır.
Yukarıdaki bilgiler doğrultusunda araştırmanın temel amacı, sosyal medya pazarlamasında kullanılan yapay zekâ teknolojilerinin, Y ve Z kuşağına mensup bireylerin tüketim alışkanlıkları üzerindeki rolünü ortaya çıkarmaktadır. Nitel araştırma yöntemlerinden derinlemesine görüşme yöntemine başvurularak gerçekleştirilen araştırmada, yapay zekâ uygulamaları kuşaklar arasındaki farklılıklar ekseninde irdelenmektedir. Araştırma bulgularına göre her iki kuşağına mensup katılımcıların, yapay zekâ temelli uygulamalarını deneyimleme pratikleri ve takip etme motivasyonlarında etkileşim unsurunun önemine yönelik farklılıkların ortaya çıktığı tespit edilmiştir. Ayrıca kullanıcıların yapay zekâ temelli uygulamalara yönelik deneyimleri Z kuşağı üzerinde tüketim alışkanlıklarını olumlu yönde güdülerken, Y kuşağına mensup kullanıcılar üzerinde daha zayıf bir motivasyon sağladığı görülmektedir. Bu bağlamda Y ve Z kuşağına mensup kullanıcıların sosyal medya pazarlamasının geleceğinde yapay zekâ uygulamalarının daha fazla önem kazanacağına ilişkin ortak bir bakış açısına sahip oldukları öne çıkmaktadır.
Possessives and spatial expressions in Spanish
Authors: Fernandez Soriano Olga , Ordoñez Francisco
Published: June 2024

The aim of this paper is to analyze a type of Spanish (and Romance) complex locative non-directional prepositional expressions taking a genitive complement, like encima/cerca de (“on top/near of”). We will center our attention on an alternation that has gone unnoticed by most theoretical and descriptive grammars: this genitive complement may appear as an argument of the main predicate and show dative case (se sentó encima de Juan, “(S)he sat on top of Juan” > se le sentó encima, “Lit. (S)he DAT sat on top”). Most of these complex PPs may correspond to what has been called ‘Axial Parts’ (Svenonius 2006, 2008), but the paradigm extends to other cases. Based on work by Larson and Samiian (2021) on the typology of nominalization in prepositions in Iranian Persian, we show that the common property of these prepositional expressions is that they contain a nominal element: a relational noun or a nominalized preposition. Apart from the dative alternation, one of the properties shown by complex locative prepositions in Spanish is that a stressed postnominal possessive is allowed, which can be masculine or feminine, giving rise to dialectal variation: detrás mío/mía, Lit. “behind mine”, cerca mío/mía, Lit. “near mine”. We will show that what determines the gender of the possessive is the nominalizer and the level of grammaticalization of the nominal head.
10.5569/2340-5104.12.01.02
Authors: Fernández Gutiérrez Rubén , Fernández Álvarez Natalia , Morán Suárez María Lucía , Solís García Patricia , Fontanil Yolanda , Alcedo Mª Ángeles
Published: June 2024

Violence against women with disabilities constitutes a significant social issue that impacts various aspects of their lives. Therefore, this study aims to: (a) identify the types of violence they suffer and possible differences based on the type of disability, and (b) determine the consequences of violence. A literature review was conducted following PRISMA criteria in the Web of Science, PsycINFO, and Scopus databases. A total of 28 articles met the inclusion criteria. The results show that women experience various types of violence, with sexual violence being particularly prevalent among women with intellectual disabilities. Violence is mainly perpetrated by their partners and caregivers. These situations generate negative consequences in all areas of their lives and hinder their social inclusion. It is necessary to reach a consensus on more precise criteria for categorizing the different forms of violence, increase research on risk factors associated with each type of violence and disability, as well as implement intervention programs tailored to the specific needs of women victims of violence.
El papel de la arquitectura en los centros de atención a la dependencia
Authors: Pozo Menéndez Elisa , Cambra-Rufino Laura , Jiménez Martín Delfín , Zarco Colón Juan
Published: June 2024

La adecuación de los centros residenciales sociales a la Estrategia estatal de Desinstitucionalización requiere de una serie de cambios y transformaciones que afectan al espacio físico donde tiene lugar el día a día de las personas que lo habitan y utilizan. El objetivo de este estudio es analizar el impacto de las limitaciones arquitectónicas para las personas con discapacidad que viven en centros de carácter institucional. Para ello, utilizamos el método de análisis temático inductivo en 24 entrevistas y 2 grupos focales realizadas a un total de 45 personas de tres centros españoles (incluyendo perfiles profesionales sanitarios, técnicos, personas usuarias y familiares). Los resultados se organizan en cuatro temas principales: 1) Relación del edificio hacia el exterior; 2) Instalaciones obsoletas y problemas de mantenimiento; 3) Inseguridades derivadas; y 4) Criterios organizativos y estructurales. En definitiva, los centros analizados presentan carencias graves que limitan la autonomía de las personas con o sin discapacidad que residen o que hacen uso de ellos. Más estudios son necesarios para promover tipologías, programas funcionales y criterios de diseño basados en evidencias, alineados con políticas públicas, que fomenten la autonomía e independencia de las personas con diversidad funcional. Asimismo, es necesaria también la promoción de una mayor relación con la comunidad y el entorno circundante, y un diseño más ergonómico y saludable para todas las personas, incluido el personal trabajador de este tipo de dotaciones y equipamientos.
The Business of Medical Writing: Financial Acumen
Authors: Affleck Joan , De Bellis Dominic , Bass Brian , Towles Jeanette
Published: June 2024

A high-performing medical writing team begins and ends with talented writers, editors, and leaders who understand their mission and their business. A panel of writers comprising the authors convened virtually on October 28, 2021, at the American Medical Writers Association national conference to discuss this topic. The topics of value proposition and business models; communication, leadership, and corporate responsibility; and financial acumen are reprised in this 3-part series. The series also includes thoughts from the authors looking to the future of the business of medical writing, including what we can do in the medical writing community to introduce these topics earlier in the medical writing career path. This Part 3 manuscript focuses on financial acumen.
From Public Health to Patient Education
Authors: Petrus Cecilia , Henderson Kelly
Published: June 2024

Kelly Henderson, MScPH, defies the conventional path to medical writing with a rich background in journalism, teaching, public health, and humanitarian work. This article delves into Kelly's nonlinear career trajectory, providing insights and tips for individuals in similar circumstances aspiring to venture into medical writing.
Product Showcase: Copilot by Yseop
Authors: Calder Moira
Published: June 2024

This piece was created based on a product information session presented at the 2023 AMWA Conference. Sponsorship of product showcases at the Medical Writing & Communication Conference does not convey AMWA's approval, endorsement, or certification of any product or service promoted and shall not, in any way, imply such approval.
Sintomas preditores de Depressão entre estudantes adolescentes do nordeste brasileiro no período pós-pandêmico
Authors: Silva Eliane Rodrigues de Carvalho , Aquino Jael Maria de , Lima Angélica de Godoy Torres , Brandão Neto Waldemar , Lima Ana Karina Moutinho , Veríssimo Ana Virgínia Rodrigues , Silva Felicialle Pereira da
Published: June 2024

Introdução: Dentre os transtornos emocionais, a depressão ocupa um lugar de destaque, pois atinge o ser humano nos diferentes momentos de sua vida, desde a infância, adolescência, até a vida adulta, constituindo-se numa carga de doença expressiva, com prejuízos na vida escolar, nas relações familiares e sociais desses indivíduos. Objetivo: Analisar a prevalência e os fatores associados à depressão em adolescentes de uma escola pública de uma capital do nordeste brasileiro. Método: Pesquisa transversal, analítica e quantitativa, realizada com 73 adolescentes de uma escola da rede pública estadual, no período de agosto a outubro de 2022. Foi aplicado um questionário sociodemográfico, o AUDIT (Alcohol Use Disorder Identification Test) e o CDI (Child Depression Inventory), para avaliar consumo de álcool e sintomas depressivos. Realizaram-se testes de hipóteses estatística, considerando nível de significância de 5% Resultados: Identificou-se uma prevalência de 30% de sintomas depressivos. Entre os fatores que contribuem para a depressão estão o sexo feminino, não gostar de ir à escola e ter uma relação ruim com os professores, faltar mais a escola e mais horas de acesso à internet, já ter experimentado bebida alcoólica e/ou consumi-la habitualmente e ter renda familiar maior que um salário mínimo. Conclusão: Devido à alta prevalência de sintomas depressivos nesta população, sugere-se a criação de espaços de escuta individual e em grupo, por profissionais da psicologia dentro do ambiente escolar.
Carrier frequency of autosomal recessive disorders CVM and DUMPS in Sahiwal and Holstein Friesian cattle in Chhattisgarh
Authors: KUMAR VINEET , JAIN ASIT , JAIN TRIPTI , MUKHERJEE KISHORE , RATHORE AAKANKSHA , PARVEEN KAISER , ANSARI FARHEEN
Published: June 2024

In the present study, genetic screening of Sahiwal and Holstein Friesian (HF) cattle and its crosses was conducted using the PCR-RFLP technique to detect the presence of CVM and DUMPS disorders. Genomic DNA was extracted from 50 Sahiwal and 100 HF animals and its crosses using commercially available kits. Gene-specific primers were utilized for in vitro amplification of SLC35A3 and UMPS genes by PCR, followed by RFLP analysis using PstI and AvaI restriction endonucleases for CVM and DUMPS, respectively. Subsequently, the PCR products were purified and sequenced to confirm any mutations in the DNA target sequences. Notably, no affected or carrier animals for CVM and DUMPS disorders were identified among the screened animals. Thus, the gene and genotype frequency of CVM and DUMPS carriers was zero, indicating a 100% frequency of normal animals. The study underscores the importance of continued screening for these genetic disorders, involving a larger sample size across the state, and advocates for mandatory screening before utilizing animals for breeding purposes, in adherence to minimum standard protocols.
The Role Of Organizational Competence And Commitment On Employee Performance With Innovation Behavior As An Intervening Variable
Authors: Sri Mertiningsih  , Legiman Legiman  , Syamsul Haris
Published: June 2024

This study aims to identify the role of employee competence and organizational commitment on employee performance, with innovative behavior as an intervening variable. Due to the population being less than 100 respondents, the study uses a census technique, taking all 50 employees of the Fisheries and Marine Office as the sample. Path analysis is employed as the data analysis technique. The results show that competence has a positive and significant effect on employee performance, organizational commitment also has a positive and significant effect on employee performance. Furthermore, competence has a positive and significant effect on innovative behavior, and organizational commitment similarly has a positive and significant effect on innovative behavior. Innovative behavior itself has a positive and significant effect on employee performance. It is also found that innovative behavior can mediate the competency variable on employee performance, and innovative behavior can also mediate the organizational commitment variable on employee performance.
The Influence Of Work Motivation And Leadership On Performance
Authors: Sabar Iman  , Addin Widi Wicaksono  , Tina Ika Vidyana
Published: June 2024

This research investigates the impact of work motivation and leadership, mediated by job satisfaction, on employee performance in savings and loan cooperatives during the Covid-19 pandemic in Pemalang. The population consists of employees from Koperasi Simpan Pinjam Muti Artha Utama, Graha Mandiri, and Merdeka Makmur the Main Branch Office in Pemalang, totaling 250 individuals. Data collection is conducted through a questionnaire, and the validity and reliability of the instruments are assessed through appropriate tests. The analytical approach involves multiple regression analysis. The findings from the multiple regression analysis indicate that work motivation positively and significantly affects employee performance, while leadership also demonstrates a positive and significant impact on employee performance. Furthermore, work motivation is found to exert a positive and significant influence on job satisfaction, and leadership similarly shows a positive and significant impact on job satisfaction. Job satisfaction is then identified as having a positive and significant effect on employee performance. The results suggest that job satisfaction serves as a mediator, enhancing or fortifying the influence of work motivation variables on employee performance. Similarly, job satisfaction acts as a mediator, amplifying the impact of leadership variables on employee performance within savings and loan cooperatives in Pemalang.
The Effects of Different Water Treatments on the Growth, and Health of Ornamental Fishes Raised under the Water Conditions
Authors: M Navaneethan , S Raja
Published: June 2024

In freshwater fish culture, water quality poses a serious hazard to survival and growth. To understand this high-risk factor associated with the poor water quality in the aquarium system, the hematological, histological, immunological, antioxidant, and growth performance of C. auratus, C. carpio, and P. hypophthalmus in the aquarium with different water treatment efficiencies and one without water filtration were compared. The experiment was conducted for approximately 120 days using water treatments: 1. PF, 2. BF, 3. PBF, 4. PBUVF, 5. WoF. Results showed that Fish health concerning turbidity (98%) was significantly reduced during post-filtration (PF, BF, PBF, and PB-UV-F) (p<0.05). In experimental tanks, water-treated fish showed improved growth and a 90% survival rate (p<0.05). In pot and bamboo filters, the hematological parameters such as RBC (93%, 94%, and 93%), WBC (79%, 18%, and 91%), and MCHC (93%, 45%, and 90%) were in the optimum levels during post filtration experiment. The immune response (IgM, C3, C4, NOS, and LSZ) of enzyme activities in the gut and liver of aquarium fishes and antioxidant parameters in the gut and liver (ABTS, CAT, GR, SOD, and LPO) were also the low-risk level where the water treatments in the aquarium tanks. In conclusion, our findings show that installing filtration systems in freshwater fish culture has helped to successfully regulate the fish health and water quality of aquariums and ensure their proper maintenance.
Desafíos y estrategias en el proceso de redacción: Una revisión sistemática
Authors: López Chumbe Mark , Cangalaya Mauricio Evelyn Yackelyn
Published: June 2024

Sintetizar el conocimiento disponible sobre los desafíos presentes en el proceso de redacción en diversos contextos y las estrategias propuestas para superarlos, con el fin de proporcionar una perspectiva estructurada y amplia para mejorar la habilidad de escritura. Se realizó una revisión sistemática integradora, aplicando la metodología Prisma, de artículos publicados entre los años 2019 y 2023 en las bases de datos Scopus y Web of Science, utilizando la ecuación de búsqueda: ("Writing" OR "writing strategies" OR "writing process") AND "writing challenges". Se establecieron y aplicaron criterios de inclusión y exclusión para seleccionar estudios pertinentes al tema de los desafíos y estrategias en el proceso de redacción. Se incluyen y analizan 15 publicaciones académicas que abordan los desafíos y estrategias en el proceso de redacción, enfocándose en estudiantes de diversos niveles educativos y personal académico. La evidencia científica ha demostrado que los desafíos de escritura son comunes entre estudiantes y académicos, pero estrategias efectivas como talleres, gráficos organizadores digitales, y retroalimentación personalizada pueden ayudar a superar estos obstáculos y mejorar las habilidades de escritura
Մայր Աթոռ Ս․ Էջմիածնի շուրջ կատարվող իրադարձությունները 1720-ական թթ․ հայ ազատագրական պայքարի ընթացքում
Authors: Շահբազյան Արմինե
Published: June 2024

Данная статья посвящена описанию событий, происходящих вокруг Первопрестольного Святого Эчмиадзина в 20-х годах 18-го века в контексте освободительной борьбы, разворачивающейся в Арцахе и Сюнике. Цель статьи — на основе имеющихся исследований представить выборы Католикоса, а также показать возникшие за это время трудности и пути их преодоления. В методологическом отношении мы попытались сравнить имеющиеся материалы и подвергнуть их историческому анализу. При написании этой работы мы поставили задачу также коснуться такого важного аспекта, как сотрудничество духовных и светских деятелей в ходе армянской освободительной борьбы, особенно отношения к этой национально-освободительной борьбе Католикосов Аствацатура и Карапета. Тема актуальна еще и тем, что как в прошлом, так и в настоящее время Арцах и Сюник были в центре внимания врагов, и необходимо понимать, что беспристрастное изучение национально-освободительных войн важно для того, чтобы сделать правильные выводы и в нынешней ситуации, а также подчеркнуть важность поддержки духовного сословия, которая всегда была необходима во все времена.
This article is devoted to the description of the events that took place around the Mother See of Holy Etchmiadzin in the 1720s, in parallel with the liberation struggle that unfolded in Artsakh and Syunik. The aim of the article is to present the election of the Catholicos, the difficulties that arose during that time and their overcoming on the basis of the existing research. We tried to compare the available materials with the historical analysis. When writing the article, we set the task to touch upon the cooperation of spiritual and secular figures during the Armenian liberation struggle, especially the attitude of the Catholicoi Astvatsatur and Karapet towards the liberation struggle. The topic is actual because both in the past and in the present, Artsakh and Syunik were the focus of the enemies’ attention, and it is necessary to understand that an impartial study of the national liberation battles is important in order to draw the right conclusions in the current situation and to emphasize the importance of supporting the clergy, which was necessary at all times.
ԴԻՔԷՆՍԻ «ՍՈՒՐԲԾՆՆԴԵԱՆ ԵՐԿԵՐԸ» ՀԱՅ ԳՐԱԿԱՆ ԱՒԱՆԴՈՅԹԻ ԼՈՅՍԻ ՆԵՐՔՈՅ
Authors: ԳԱՍՊԱՐԵԱՆ ԼՈՒԻԶԱ
Published: June 2024

Ամփոփում:
Յօդուածը նուիրուած է ԺԹ․ դարավերջի եւ Ի․ հարիւրամեակի սկզբի ռուս եւ հայ գրական- մշակութային միջավայրում Չարլզ Դիքէնսի՝ «Սուրբ Ծննդեան պատմութիւնների » գրական ազդեցութեան վերհանմանը: Մշակութային փոխանցման լոյսի ներքոյ ուրուագծւում են գեղարուեստական թարգմանութեան հայեցակարգին վերաբերող մի շարք հարցադրումներ` ի յայտ բերելով Դիքէնսի վէպերի ժառանգութեան եւ թարգմանութիւնների գործուն ընկալման իրողութիւնները Հայաստանում (յատկապէս Արևելեան Հայաստանում) ։ Ցաւով նկատւում է, որ հայերէն թարգմանութիւնները մեծաւ մասամբ կատարուել են ռուսերէն թարգմանութիւնների «միջնորդութեամբ »: Աւելին, ուսումնասիրութիւնը ցոյց է տուել, որ «Սուրբ Ծննդեան պատմութիւնների » վաղ թարգմանութիւնները ենթարկուել են զգալի ձևափոխութիւնների` ելնելով ռուս եւ հայ լեզուամշակութային առանձնայատկութիւններից: Հիմնուելով Դիքենսի ստեղծագործութիւններին՝ իբրև եզրակացութիւն նշւում է, որ վաղ վիկտորիանական շրջանի Անգլիայի ընկերային- մշակութային համապատկերը գրեթէ հաւասարապէս հեռու է ռուս եւ հայ իրականութիւնից: Յարդիւնս ասուածի մշակութային փոխանցումը յանգեցրել է թարգմանութիւնների զգալի փոփոխութեան:
Статья посвящена исследованию литературной роли книги «Рождественские повести» Диккенса в русской и армянской литературной средах конца XIX и начала XX веков. Обозначается спектр вопросов касательно концепции художественного перевода в свете культурного трансфера. В анализе очерчивается ситуация активной рецепции наследия и переводов произведений Диккенса в Армении (особенно в Восточной Армении) конца XIX, которые, в большинство случаев, переводились через «посреднической» роли русских переводов. Исследование показало, что ранние переводы «Рождественских повестей» были видоизменены: наблюдаются определенные трансформации, обусловленные лингво-культурными особенностями как русской, так и армянской среды. Делается вывод, что социокультурный контекст ранней викторианской Англии (на материале работ Диккенса) практически одинаково чужд как русским, так и армянским культурным реалиям. Соответственно, культурный трансфер привел к значительной модификации переводов с целью более плавного восприятия контекста, в существенно отличающихся социокультурных и геополитических условиях.
ԿԵՐՊԱՐԱԿԵՐՏՄԱՆ ԱՌԱՆՁՆԱՅԱՏԿՈՒԹԻՒՆՆԵՐԸ
ԼԵՒՈՆ ԲԱՇԱԼԵԱՆԻ ԱՐՁԱԿՈՒՄ
Authors: ԱՆԴՐԷԱՍԵԱՆ ԹԱՄԱՐԱ
Published: June 2024

Ամփոփում:
The article touches upon the peculiarities of character development in the works of Levon Bashalian. Drawing on the insights of analytical psychology, we have conducted a psychological and profound analysis of characters, as evidenced by the works of Z. Freud and K. G. Jung. The article delves into numerous issues, shedding light on them through the lens of contemporary literary studies. Various approaches have been employed to examine the psychological traits of the protagonists depicted in novels and short stories։ • The actions of characters demonstrating depressive and isolated traits in social relationships were elucidated through an examination of the impact of the social environment and individual characteristics. • For behavioral analysis of characters, the portrait with a socio-psychological and national layer was employed to enhance the comprehensive psychological depiction of the character. • Special attention was given to the description of the physical environment and natural phenomena, serving as a means to gain psychological insights.
В статье затрагиваются особенности создания образов Левона Башаляна. С целью глубокого, психологического анализа образов нами был использован опыт аналитической психологии, ссылаясь на взгляды З. Фрейда, К. Юнга. Многие вопросы в статье трактуются исходя из современного литературоведческого опыта. Черты душевного склада героев, встречающихся в новеллах и рассказах, были рассмотрены по нескольким методам: • Действия образов, которые в общественных отношениях демонстрируют подавленные, изолированные черты характера, обусловлены ролью социальной среды и личностными свойствами. • Для поведенческого анализа образов был использован портрет — с национальными, социально-психологическими слоями, что помогло обобщить психологическое описание характера. • Подчеркивается значимость описания социума, окружающей среды, природных явлений, через которые возможны психологические проникновения.