bluuebunny/crossref_metadata_2025 huggingface dataset:
Konwencjonalne modele scenariusza filmowego i ich kulturowe modyfikacje
Authors: Błaszczok Adam
Published: January 2025

Celem przedstawionego artykułu jest ukazanie – ze szczególnym uwzględnieniem punktu widzenia praktyki branżowej – różnic w podejściu twórców europejskich i amerykańskich do zagadnienia wykorzystywania w produkcji filmowej konwencjonalnych modeli scenariuszy filmowych. Zdaniem autora publikacji funkcjonujące w tym obszarze odmienne praktyki wynikają z kilku zasadniczych przyczyn, do których można zaliczyć przede wszystkim różnice kulturowe i społeczne – co bezpośrednio wpływa na inne podejście do problemu finansowania produkcji filmowej. Wskazane zostały tendencje rozwojowe w scenopisarstwie europejskim i amerykańskim, wynikające z jednej strony z istniejących procesów globalizacyjnych i technologicznych, z drugiej zaś z pojawiających się w branży filmowej ruchów odśrodkowych. Scharakteryzowano konwencjonalne modele stosowane w produkcji filmowej z uwzględnieniem obu omawianych obszarów. Omówiono wybrane filmy reprezentatywne dla przedstawianego zagadnienia. Wykazano, że amerykański system produkcji filmowej przeważa nad europejskim zarówno pod względem organizacyjnym, jak też ze względu na poziom profesjonalizacji. Jednocześnie zwrócono uwagę  na przyspieszenie procesów globalizacyjnych w branży filmowej, które są czynnikami determinującymi zmiany zarówno w Europie, jak i w Stanach Zjednoczonych.
Relacja zbudowana na algorytmach. Co determinuje dziś treści oferowane odbiorcom przez portale informacyjne - na przykładzie serwisu rp.pl
Authors: Jarosz Marta
Published: January 2025

Wciąż postępująca rewolucja technologiczna sprawia, że treści dziennikarskie oferowane użytkownikom internetu nie są już zależne tylko od wagi podejmowanych tematów, ale w dużym stopniu również od uwarunkowań narzucanych przez algorytmy i oczekiwań samych odbiorców. Efektem tego jest konieczność rozszerzania oferty przez media do tej pory specjalizujące się w tematach związanych z polityką, prawem i ekonomią. Zjawisko, o którym mowa, obrazują zmiany, które dokonały się w ostatnim roku w portalu rp.pl. Na czym one polegały i czym zaowocowały? Co w praktyce redakcyjnej oznacza "dyktatura Google Discover"? W artykule została podjęta próba odpowiedzi na te pytania. W przedstawionych rozważaniach wykorzystane zostały praktyczne doświadczenia autorki i dane wewnętrzne wydawnictwa oraz wyniki badania ankietowego przeprowadzonego na potrzeby niniejszego opracowania.
„Actus humanus” w kontekście sztucznej inteligencji a odpowiedzialność osoby
Authors: Sobkowiak Jarosław
Published: January 2025

Celem prezentowanego artykułu jest refleksja nad zagadnieniem „actus humanus” w odniesieniu do sztucznej inteligencji (AI) oraz odpowiedzialności moralnej człowieka. W pierwszej części dokonuje się zestawienia cech charakterystycznych dla aktu ludzkiego z odpowiednikiem „aktów” sztucznej inteligencji, które są oparte na algorytmach i procesach uczenia maszynowego. W dalszej części zostają nakreślone technologiczne i etyczne ramy wykorzystania sztucznej inteligencji. W ostatniej części zostanie omówiona propozycja ograniczenia nadzoru człowieka nad procesem uczenia maszynowego i powierzenie go sztucznej inteligencji odwołującej się wyłącznie do stworzonych ram etycznych (CAI). Całość zostaje dopełniona najnowszą propozycją „Collective Constitutional AI” (CCAI), która ma poszerzyć odpowiedzialność o społeczny wymiar tworzenia ram etycznych i w ten sposób zachować pośredni nadzór człowieka nad procesami sztucznej inteligencji.
Kategoria dzieciństwa w ekspozycjach o Holokauście. Analiza strategii komunikacyjnych wybranych muzeów
Authors: Zaborski Marcin
Published: January 2025

Jak muzea poświęcone Holokaustowi prezentują historie najmłodszych uczestników wojny? Jaką rolę w ich narracji odgrywają dzieci? Czy autorzy ekspozycji poświęcają im odrębne wystawy – czy raczej dziecięce losy są „wpisane” w ogólny przekaz dotyczący historii Zagłady? Czy muzealne prezentacje są poświęcone konkretnym postaciom czy społecznościom anonimowych uczestników wojennych wydarzeń? I wreszcie – czy autorzy ekspozycji dotykających traumy dostosowują swój przekaz do możliwości percepcyjnych młodego odbiorcy? Stawiając te pytania, autor artykułu analizuje linie narracyjne wybranych placówek muzealnych: Instytutu Yad Vashem w Jerozolimie, Muzeum Żydowskiego w Berlinie, Muzeum Holokaustu w Waszyngtonie, Wileńskiego Muzeum Historii Żydowskiej, Ryskiego Muzeum Getta i Holokaustu na Łotwie oraz Estońskiego Muzeum Żydowskiego w Tallinie.
Consumption in the Developed Society and the Need to Change the Business Philosophy of Marketing
Authors: Pechočiaková Svitačová Eva
Published: January 2025

Consumption is a social activity, one of the objective prerequisites for better living conditions for people, and at the same time an important prerequisite for the functioning and development of a market economy. The study reveals that the efforts of many actors in the economy to make a profit are associated with the growth of consumption, with the development of a consumerist life strategy and a consumer culture. Consumption, on the one hand, allows individuals to liberate themselves, to express themselves, it is an expression of individualisation, but it is also a space for manipulation. In this context, attention has been drawn to certain forms of modern marketing which not only influence consumer demand or consumption, but also their lifestyles and identities. Alongside this, they promote consumerism, consumer culture and, in the long term, threaten sustainable development. In order to improve the quality of life of present and future generations the need to rethink some modern types of marketing and to change or reform the current marketing business philosophy is justified.
Avaliação da ocorrência da estomatite vesicular a partir das notificações de suspeita de síndrome vesicular no estado do ceará, brasil
Authors:   , Rocha Célio Souza da
Published: January 2025

A estomatite vesicular possui importância sócio-econômica pois é considerada
uma zoonose e interfere negativamente no rebanho com redução na produção de leite e perda
de peso levando ao abate precoce. Os sinais clínicos são indiferenciáveis daqueles causados
pelo vírus da Febre Aftosa por isso continua sendo classificada pelo Ministério da
Agricultura, Pecuária e Abastecimento como doença que requer notificação imediata de
qualquer caso suspeito sendo esta notificação obrigatória para qualquer cidadão e profissional
que atue na área de diagnóstico, ensino ou pesquisa em saúde animal. Diante disso, este
estudo objetivou investigar a ocorrência de focos de Estomatite Vesicular através dos casos
suspeitos de síndrome vesicular notificados ao Serviço Veterinário Oficial do Estado do Ceará
– Brasil. Durante o período de 2013 a 2015 foram realizadas 51 notificações de casos
suspeitos de doença vesicular. Amostras de soro sanguíneo, epitélio e líquido esôfagofaríngeo
foram coletadas de acordo com a característica das lesões encontradas e enviados ao
Laboratório Nacional Agropecuário - LANAGRO. Além disso, levantamento epidemiológico
foi realizado para identificar prováveis fatores de risco para a ocorrência da enfermidade.
Após diagnóstico laboratorial e epidemiológico, 24 propriedades foram consideradas focos.
Foi possível detectar a presença de Vesiculovírus Indiana tipo 3 por fixação de complemento
50% em 8 focos. Não foram identificados fatores de risco para a ocorrência da enfermidade
quando analisamos apenas os casos prováveis com diagnóstico laboratorial entretanto houve
diferenças significativas entre focos e não focos quando analisamos todos os casos suspeitos.
Os resultados demonstraram que a ocorrência de focos de Estomatite Vesicular no Estado do
Ceará esteve relacionada a fatores de riscos específicos como tipo de criação, utilização de
instalações ou equipamentos de vizinhos ou vice-versa, utilização de mão de obra de vizinhos
ou vice-versa, animais do estabelecimento participam de eventos de aglomerações e
proximidade ou divisa do estabelecimento com rodovias, lixões, aeroportos, frigorífico,
laticínios entre outros quando os critérios epidemiológicos foram levados em consideração
entretanto, tais achados só podem ser levados em consideração para fins de investigação
epidemiológica de casos suspeitos e mitigação de riscos. Portanto, se faz necessário maiores
estudos para descrever a transmissão desse agente infeccioso entre os rebanhos susceptíveis
no Estado através do fortalecimento do sistema de defesa sanitário.
Pinhão-bravo (jatropha mollissima pohl baill.): caracterização fitoquímica e atividades farmacológicas do látex e dos seus extratos
Authors:   , Queiroz Neto Rafael Fernandes de
Published: January 2025

O pinhão-bravo (Jatropha mollissima Pohl Baill.) é um arbusto autóctone da vegetação de caatinga, encontrada em grande parte do semiárido do Nordeste brasileiro, utilizado na cultura popular com fins terapêuticos. O látex do pinhão-bravo e os extratos dele derivados foram avaliados quanto à composição fitoquímica, identificando os principais metabólitos secundários a partir de métodos qualitativos e quantitativo, e quanto as suas atividades farmacológicas. Foram pesquisadas toxicidade, através da dose tóxica aguda em ratos Wistar, ação antioxidante, de acordo com o método fotocolorimétrico do radical livre DPPH, e ação antibacteriana, através da concentração inibitória mínima e da concentração bactericida mínima. Foram detectados fenóis, taninos, flavonoides e saponinas no látex e demais extratos pesquisados. Tanto o látex quanto o extrato etanólico apresentaram moderada atividade antioxidante, como também evidenciaram atividade antibacteriana contra as cepas Gram-positivas (Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus mutans e Enterococcus faecalis) e Gram-negativas (Shigella flexneri, Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium e Pseudomonas aeruginosa), em várias diluições, juntamente com o extrato hidroalcoólico. O látex do pinhão apresentou ainda baixa toxicidade aguda em ratos. Logo, os resultados obtidos nesta pesquisa corroboram o uso popular da J. mollissima e seu potencial terapêutico.
Caracterização espaço-temporal de atropelamentos de mamíferos silvestres em estradas inseridas no semiárido nordestino
Authors:   , Sombra Júnior Carlos Antônio
Published: January 2025

A mortalidade da fauna devido a atropelamentos constitui uma das principais ameaças à biodiversidade. Diversos fatores podem estar relacionados com a ocorrência desses atropelamentos, entre eles o intenso tráfego de veículos, a imprudência de motoristas, o deslocamento de animais atravessando as rodovias, como também os padrões de paisagem. O presente estudo teve como objetivo identificar pontos de maior atropelamento de mamíferos silvestres em estradas circundantes à Estação Ecológica do Seridó (ESEC Seridó) e a relação desses com elementos da paisagem circundante. Além disso, foi avaliada a relação entre os atropelamentos e a variação temporal. O monitoramento dos trechos escolhidos foi realizado em intervalos de 21 dias, durante 36 meses. Para a abordagem espacial, os dados foram obtidos a partir da classificação e quantificação das unidades da paisagem utilizando-se buffers com raios de 1 km, 5 km e 10 km, utilizando-se duas imagens Landsat (uma da estação chuvosa e outra da estação seca), onde classificou-se quanto à presença de corpos d’água, vegetação nativa, agricultura, solo exposto e urbanização. Para a caracterização temporal, foram utilizadas as variáveis de temperatura, precipitação pluviométrica, umidade e fotoperíodo. Utilizou-se a análise de correlação de Pearson para detectar relações significativas e testes de Akaike para identificar os modelos mais explicativos sobre as relações. Observou-se uma maior taxa de atropelamentos de mamíferos durante a época da estação seca. As espécies de mamíferos silvestres mais atingidas por atropelamentos foram Cerdocyon thous, Lycalopex vetulus e Procyon cancrivorus. Espacialmente, os hotspots da Classe Mammalia foram relacionados de forma negativa à agricultura e à urbanização, enquanto que os hotspots de Cerdocyon thous foram relacionados positivamente à vegetação nativa e negativamente à agricultura, solo exposto e urbanização, e os hotspots de Procyon cancrivorus, por sua vez, relacionados positivamente à urbanização. A espécie Lycalopex vetulus não apresentou relação significativa. Quanto às variáveis temporais, o grupo geral de mamíferos e a espécie Cerdocyon thous apresentaram relação negativa ao fotoperíodo.
Desenvolvimento de antenas de microfita com patch em espiral de arquimedes retangular
Authors:   , Vale Rafael Alex Vieira do
Published: January 2025

Este trabalho apresenta um estudo sobre as antenas de microfita com o uso de patch em forma espiral de Arquimedes. A topologia espiral apresenta a característica de operação, em antenas de microfita, em multibanda, ou seja, é capaz de ressoar em mais de uma faixa de frequência de operação. Desta forma diversifica a operação da antenas e possibilita a aplicação em muitas faixas. O trabalho apresenta também o estudo da reconfigurabilidade em frequência e em polarização das antenas de microfita. A reconfigurabilidade dinamiza a operação sendo possível a escolha das frequências de ressonâncias a ser utilizadas em um determinado serviço usando o chaveamento eletrônico como: diodos PIN e chaves MEMS. Além da reconfigurabilidade também foi trabalhada a característica de banda larga com a retirada de material condutor no plano de terra. As antenas foram simuladas e construídas para comparação dos resultados esperados neste estudo em relação frequência de ressonância, largura de banda, polarização e o comportamento do diagrama de radiação de cada uma das antenas
α-Phellandrene: A Promising Natural Remedy for Rotenone-Induced Parkinson's Disease
Authors: Kumar Ravi , Arora Swamita , Alam Sanjar , Rashid Mohammad , Kumar Shivendra
Published: January 2025

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by the pro-gressive loss of dopaminergic neurons in the substantia nigra, leading to motor dysfunction and non-motor symptoms. Current treatments primarily offer symptomatic relief without halt-ing disease progression. This has driven the exploration of natural compounds with neuropro-tective properties. In previous studies, α-phellandrene, a monoterpene present in essential oils of various aromatic plants, has shown promise in mitigating neurodegenerative processes. This study focuses on alpha-phellandrene's therapeutic potential in a rotenone-induced Parkinson's Disease model. Rotenone, a mitochondrial complex I inhibitor, is commonly used to induce PD-like symptoms in experimental models due to its ability to mimic the neurodegenerative processes observed in human PD. Our review explores the neuroprotective effects of alpha-phellandrene, focusing on its antioxidant, anti-inflammatory, and anti-apoptotic properties. Experimental groups of rodents received rotenone to induce PD-like symptoms, followed by alpha-phellandrene treatment. Biochemical analyses were performed to measure oxidative stress markers, inflammatory cytokines, and apoptotic signals in brain tissues. Results indi-cated that alpha-phellandrene administration significantly improved motor function and re-duced rotenone-induced oxidative stress, inflammation, and apoptosis in dopaminergic neu-rons. Histopathological examinations revealed a notable preservation of neuronal integrity in alpha-phellandrene-treated groups compared to controls. In conclusion, alpha-phellandrene demonstrates considerable neuroprotective effects in a rotenone-induced Parkinson's dmodel. These findings suggest that alpha-phellandrene could be a promising natural therapeutic agent for PD, warranting further investigation into its mechanisms of action and potential clinical applications. Specifically, our review indicates that alpha-phellandrene may exert neuropro-tective effects by various mechanisms, such as reducing oxidative stress, modulating neuro-transmitter levels, or inhibiting neuroinflammation. These mechanisms highlight its potential to alleviate PD symptoms and slow disease progression, underscoring the need for in-depth studies to validate these therapeutic effects in clinical settings
Ruminal Lesions in Dairy Cows Naturally Infected by Calicophoron microbothrioides (Trematoda: Paramphistomidae)
Authors: Coronado José F. , Torrel Teófilo , Vargas-Rocha Luis
Published: January 2025

Calicophoron microbothrioides is a relatively new trematode species reported in domestic ruminants in the Cajamarca Valley (Peru). This species poses a significant endemic risk to domestic ruminants in the local livestock; however, histopathological aspects of the infection remain understudied. This study aims to describe the histological ruminal lesions induced by C. microbothrioides in naturally infected Holstein cows. Ten cows were sampled, collecting 1 cm³ of rumen tissue from affected areas (rough areas without ruminal papillae) in positive cases during post-mortem inspections. Control samples were taken from the rumen tissue of cows not infected with C. microbothrioides. The samples were processed using the paraffin embedding technique and stained with hematoxylin-eosin. The rumen flukes exhibited a pink and shiny color, with a curved conical shape (concave ventral region), and the anterior section slimmer than the posterior one (length 5.45 ± 2.50 mm and width 2.8 ± 0.58 mm). Histology revealed cellular degeneration, inflammation, and tissue necrosis in all affected animals. These findings highlight the impact of C. microbothrioides infection in adult cows, leading to marked histopathological alterations in the rumen wall. Given the importance of these results, there is a need for further studies on this parasite, considering its potential threat to the health and productivity of local ruminants.
Exploring the Differentiation of Self-Concepts in the Physical and Virtual Worlds Using Euclidean Distance Analysis and Its Relationship With Digitalization and Mental Health Among Young People: Cross-Sectional Study (Preprint)
Authors: Chan Kai Tai , Hui Christy LM , Cheung Charlton , Suen Yi Nam , Wong Stephanie Ming Yin , Wong Corine SM , Kam Bosco PH , Chen Eric Yu Hai
Published: January 2025

BACKGROUND

Increasing observation and evidence suggest that the process of digitalization could have profound impact to the development of human mind and self, with potential mental health consequences. Self-differentiation is important in human identity and self-concept formation, which is believed to be involved in the process of digitalization.

OBJECTIVE

This study aimed to investigate the relationship between digitalization and personal attributes in the actual selves in the physical and virtual worlds.

METHODS

A community cohort of 397 participants aged 15 to 24 years old was recruited consecutively over about 3 months. Assessment was conducted upon the indicators of digitalization (smartphone use time, leisure online time, and age of first smartphone ownership), smartphone addiction, 14 selected personal attributes in the actual selves in the physical and virtual worlds, psychiatric symptomatology and personality traits. Euclidean distance analysis between the personal attributes in the actual selves in the physical and virtual worlds for the similarities of the 2 selves was performed in the analysis.

RESULTS

The current primary findings are the negative correlations between the similarity of the personal attributes in the physical actual self and virtual actual self, and smartphone use time, smartphone addiction as well as anxiety symptomatology respectively (P<.05 to P<.01).

CONCLUSIONS

The current findings provide empirical evidence for the importance of maintaining a congruent self across the physical and virtual worlds, regulating smartphone use time, preventing smartphone addiction, and safeguarding mental health.
Examining Health Care Provider Experiences With Patient Portal Implementation: Mixed Methods Study (Preprint)
Authors: Taneja Shipra , Kalia Kamini , Tang Terence , Wodchis Walter P , Vanderhout Shelley
Published: January 2025

BACKGROUND

Health systems are increasingly offering patient portals as tools for patients to access their health information with the goal of improving engagement in care. However, understanding health care providers’ perspectives on patient portal implementation is crucial.

OBJECTIVE

This study aimed to understand health care providers’ experiences of implementing the MyChart patient portal, perspectives about its impact on patient care, clinical practice, and workload, and opportunities for improvement.

METHODS

Using an explanatory sequential mixed methods approach, we conducted a web-based questionnaire and semistructured individual interviews with health care providers at a large Canadian community hospital, 6 months after MyChart was first offered to patients. We explored perspectives about the impact of MyChart on clinical practice, workload, and patient care. Data were analyzed using descriptive statistics and thematic analysis.

RESULTS

In total, 261 health care providers completed the web-based questionnaire, and 15 also participated in interviews. Participants agreed that patients should have access to their health information through MyChart and identified its benefits such as patients gaining a greater understanding of their own health, which could improve patient safety (160/255, 62%). While many health care providers agreed that MyChart supported better patient care (108/258, 42%), there was limited understanding of features available to patients and expectations for integrating MyChart into clinical routines. Concerns were raised about the potential negative impacts of MyChart on patient-provider relationships because sensitive notes or results could be inappropriately interpreted (109/251, 43%), and a potential increase in workload if additional portal features were introduced. Suggested opportunities for improvement included support for both patients and health care providers to learn about MyChart and establishing guidelines for health care providers on how to communicate information available in MyChart to patients.

CONCLUSIONS

While health care providers acknowledged that MyChart improved patients’ access to health information, its implementation introduced some friction and concerns. To reduce the risk of these challenges, health systems can benefit from engaging health care providers early to identify effective patient portal implementation strategies.

CLINICALTRIAL
Evaluating Social Assistive Robots in Clinical Nursing Care: A Pilot Study on Healthcare Workers’ Perceptions and Adoption (Preprint)
Authors: Leoste Janika , Lubi Kadi , Marmor Kristel , Kangur Katrin
Published: January 2025

BACKGROUND

The growing demand for elderly care due to aging populations and healthcare workforce shortages requires innovative solutions. Socially assistive robots (SARs) are increasingly explored for their potential to reduce workload by handling routine tasks. Yet, adoption can be hindered by various healthcare workers’s concerns.

OBJECTIVE

This study examined the perceptions of healthcare workers toward SARs before and after a pilot use in a clinical nursing care setting. The study focused on SAR usability, emotional appropriateness, and readiness for adoption.

METHODS

A mixed-methods pilot study was conducted at the East Tallinn Central Hospital’s Nursing Care Clinic in collaboration with Tallinn University of Technology. The TEMI v3 robot was used for two weeks for visitor guidance, goods delivery, and patrolling tasks. Healthcare workers filled in pre- and post-intervention surveys with Likert-scale items and open-ended questions. Quantitative data were analyzed for changes in perceived safety, trust, and usability. Qualitative data underwent thematic analysis to understand participants’ opinions.

RESULTS

Out of 45 involved healthcare workers, 20 completed the pre-test survey, and 5 completed the post-test survey. Pre-test results show limited previous exposure to SARs (85%) and mixed perceptions of their role, with 45% viewing SARs as machines and 30% as somewhat human-like. Although 60% believed SARs could become mainstream within 5-10 years, there were concerns about the robot’s emotional adequacy and job displacement. Post-test findings showed increased confidence in SARs, with all respondents perceiving them as safe tools. Qualitative results indicate improved trust and readiness to integrate SARs into daily routines, with 80% being willing to advocate for SAR use. Still, participants noted limited impact on facilitating their jobs.

CONCLUSIONS

The study indicates that short-term collaboration with SARs can enhance healthcare workers’ confidence and their readiness for adoption. However, actual use would need proper emotional adequacy from the robot and aligning its functionalities with specific care needs. The future studies need to examine long-term impacts on care quality and job satisfaction, and also strategies to address generational differences and technophobia among healthcare staff. Transparent communication and proper training are required for ensuring acceptance.

CLINICALTRIAL

This trial was registered with the Research Ethics Committee of the National Institute for Health Development in Estonia under protocol number #8.3/13-24, dated May 29, 2024.
Exploratory Impact of iCARE Nigeria, a combined mHealth and Peer Navigation Intervention, on Depressive Symptoms and Substance Use Among Youth Living With HIV In Nigeria: a single-arm trial (Preprint)
Authors: Ogunmola Olusegun Ayomikun , Tamambang Rita Frinue , Kuti Kehinde , Kuhns Lisa , Awolude Olutosin , Adetunji Adedotun , Oladeji Bibilola , Olaleye Oladayo , Oyerinde Adeola Mary , Garofalo Robert , Taiwo Babafemi , Omigbodun Olayinka Olusola
Published: January 2025

BACKGROUND

Mental health problems are a barrier to the wellbeing of youth living with HIV (YLWH). Many YLWH in Nigeria face peculiar bio-psycho-social vulnerabilities that predispose them to mental health problems including depression and substance use. In addition to improving treatment outcomes like medication adherence and linkage to care, peer engagement has shown some promise in improving the social and emotional wellbeing of this population. Mobile health (mHealth) interventions like SMS may also contribute to better outcomes in YLWH. Emerging evidence suggests that combination interventions may be more effective than single interventions in improving key HIV testing and treatment outcomes among youth in Nigeria.

OBJECTIVE

To explore the impact of Intensive Combination Approach to Rollback the Epidemic in Nigerian Adolescents Study (iCARE Nigeria)— an mHealth+peer navigation intervention primarily aimed at medication adherence and viral suppression— on depressive symptoms and substance use among YLWH in Nigeria.

METHODS

A single-arm clinical trial was conducted at the Infectious Disease Institute (IDI), College of Medicine, University of Ibadan, Nigeria— primarily to improve medication adherence and viral suppression among YLWH attending its HIV clinic. The intervention combined peer navigation and daily, two-way, text message medication reminders delivered over a period of 48 weeks. Participants were screened at baseline and follow-up visits (24 and 48 weeks) for depression and substance use using standardized measures. Paired t-tests and McNemar’s tests were used to investigate the change in depressive symptoms and the change in the proportion of participants reporting substance use over time, respectively.

RESULTS

All 40 enrolled participants (50% male; mean age 19.9, SD 2.5 years) completed baseline and follow-up visits at week 24, while 37 (92.5%) participants completed the week 48 visit. Compared with baseline, there were significantly fewer self-reported depressive symptoms observed at 48 weeks (t36=2.04, P=0.048) but not at 24 weeks (t36=0.47, P=0.644). There were fewer self-reports of substance use at weeks 24 and 48 when compared to baseline, but these were not statistically significant (P=0.50 and P=0.625 respectively).

CONCLUSIONS

These findings suggest a reduction in depressive symptoms among YLWH over the 48-week intervention period that may be partly due to the iCARE Nigeria intervention.
Mobile apps for oncology health care professionals: a mapping and assessment study (Preprint)
Authors: Liñares David , Nicolaidou Iolie , Charalambous Andreas , Cabutto Daniela , Moreno-Alonso Deborah , Madrid Alejos Clara , Couespel Norbert , López-Rey Noemí , Fernández-Domínguez María José , Carrion Carme , Clavería Ana
Published: January 2025

BACKGROUND

Mobile apps are increasingly being used to manage cancer, however not without challenges. Despite their potential, evidence on the actual use of mobile technologies within the cancer care context is not adequate. Areas of concern include healthcare professionals’ (HCP) challenges in identifying the most suitable applications for their specific needs, as well as in evaluating these apps' quality and clinical effectiveness.

OBJECTIVE

The present study aims to: (a) map the landscape of free mobile apps for cancer prevention, treatment, therapy, or support for HCPs, and (b) assess the quality of the applications identified

METHODS

A systematic search of apps in Google Play and the AppStore was conducted according to predefined keywords words and applying the PRISMA guidelines. Searches were performed in May 2023 and November 2024. Apps were independently assessed by two reviewers using the Mobile App Rating Scale (MARS).

RESULTS

The search identified 221 apps. After the screening phase, 20 mobile apps that met the inclusion criteria were evaluated and prioritized by MARS peer review. The mean score was 3.51, with only two applications exceeding the 4-point threshold, which is considered to indicate a ‘good’ level of quality

CONCLUSIONS

This study provides a ranking of cancer-related apps for HCPs, detailing the strengths and limitations of each to aid in curating useful digital resources. Despite the generally low quality observed, the ONCOassist app showed notable potential utility. The findings underscore a lack of robust evidence in current literature supporting the effectiveness of health apps for cancer care.
Prologue: Drawing On 'Plenitude and Emptiness'
Authors: Wiszniewski Dorian
Published: January 2025

Read online at: https://drawingon.org/Issue-01-PR-Prologue
The state of development of the soybean industry in China
Authors:   Cheng District Center for Advanced Agricultural Technology, Lee I.
Published: January 2025

The article presents the results of studying the state of development
of the soybean industry in China. The dynamics of acreage, soybean production volumes, its yield, import volumes, and price trends are considered. The characteristic
problems of soybean production in China are highlighted. It was revealed that the
increase in production rates is a key factor leading to an increase in the volume of
soybean imports annually.
The results of biotesting soil containing heavy metals
Authors:   Siberian Federal Scientific Center of Agricultural Biotechnology of the Russian Academy of Sciences, Altaev Alexander A.
Published: January 2025

The article discusses the methodology and results of biotesting soil contaminated with heavy metals. The indicators of plant growth and development in the
vegetative laboratory experiment to determine the phytotoxicity of the studied soil are
given. In the experiment were used the seeds of the flora of Transbaikalia – Larix
sibirica, Elymus sibiricus, Bromopsis inermis, Melilotus albus и Festuca ovina.
The effect of direct sowing on the photosynthetic activity of soybeans of the Debut variety
Authors:   Far Eastern State Agrarian University, Getmanskiy Valentin V. , Tikhonchuk Pavel V. ,   Far Eastern State Agrarian University, Zakharova Elena B. ,   Far Eastern State Agrarian University
Published: January 2025

The article describes the impact of soybean cultivation technology
with tillage and technology of its cultivation without tillage (direct sowing) in the
corn-for-grain – soybean crop rotation, the photosynthetic potential, the net productivity of photosynthesis, as well as the yield of soybeans.
The productivity of the Debut soybean variety depends on different methods of sowing and fertilization
Authors:   Far Eastern State Agrarian University, Zakharova Elena B. , Minkach Tatyana V. ,   Far Eastern State Agrarian University, Konyushkov Andrey I. ,   Far Eastern State Agrarian University
Published: January 2025

The results of research on the agricultural technology of soybeans
of the Debut variety are presented. The field experiment was conducted in typical conditions for the southern agricultural zone of the Amur region. It was found
that cultivation with row spacing of 30 cm and the introduction of sulfoammophos
100 kg/ha provides an increase in the yield of soybean of the Debut variety by
5.5% than with row spacing of 15 cm; by 23% compared with the option without
fertilizer and by 9% compared with the introduction of azofosk.
FROM LYRICS TO LEARNING: THE EFFECT OF SONGS ON STUDENTS' MOTIVATION TO LEARN ENGLISH
Authors: Sholihah Ayu Ni’matus , Hossain Rumana , Farid Achmad , Yusuf Adi
Published: January 2025

The research aims to investigate the impact of popular English songs on students' motivation to learn English at School X in Jombang using a quasi-experimental design. This study focuses on implementing English popular songs (EPS) popular in the last 15 years and remain popular today. A sample of 42 students from two different classes participated in the study. Data were gathered using a questionnaire and analyzed statistically with SPSS version 20. The findings indicate that students' motivation to learn English was moderate, based on their responses to the Likert scale questionnaire. Furthermore, Spearman's rank correlation test found a moderate correlation between students' motivation and the use of EPS. In light of these findings, using EPS does not significantly affect students' motivation. However, it was noted that students' learning experiences, a component of the L2 Motivational Self System, improved. Additionally, a Chi-square test of independence examined the relationship between the frequency of students listening to EPS and their motivation. The results suggest that students who frequently listen to English songs tend to have higher motivation. This study provides insights into the potential benefits of incorporating popular music into English language learning to enhance student engagement and motivation.
Dissolution effects on clumped isotope signatures in planktic foraminifera
Authors: Tandy Hannah Tylee , Flores Randy , Subhas Adam V. , Schmidt Daniela N , Khan Khushboo Tanya , Gwak Soyoun , Savage Lina , Eagle Robert , Tripati Aradhna
Published: January 2025

The carbonate clumped isotope paleothermometer is becoming more widely
used in the geosciences because it is less sensitive to solution
δ18O and Mg/Ca than other carbonate-based temperature
proxies. Here, we examine the impacts of dissolution on foraminiferal
clumped isotope records (∆47). Dissolution is known to
impact carbonate minerals in ocean sediments near and below the
carbonate saturation horizon. The effects of dissolution on
foraminiferal mass, δ18O, and Mg/Ca have been the
subject of prior work but have not yet been reported for the carbonate
clumped isotope paleothermometer. We examine six planktic foraminiferal
species from core-tops collected at different water depths on the Ontong
Java Plateau. Below the carbonate saturation horizon, multiple species
exhibit higher ∆47 values, likely due to dissolution,
biasing ∆47 to cooler temperatures. The largest effects
are observed in G. siphonifera, P. obliquiloculata, and
G. tumida with an ~0.01 ‰ difference from above
to below the saturation horizon; p < 0.01 corresponding
to a temperature bias of ~4 °C at a measured temperature
of 28 °C and of ~3 °C at a measured temperature of 18
°C. Normalizing data for different species yields a pooled slope of
-0.0006 ‰/µmol/kg ∆[CO32-] (p
< 0.01). Dissolution experiments show that for two species,
T. sacculifer and G. tumida, ∆47 increased
with mass loss. We propose multiple mechanisms by which dissolution may
impact ∆47 including intra-test heterogeneous
dissolution, which provide context to enable corrections for the impacts
of dissolution on clumped isotope-based paleo-records.
Screening for metabolic dysfunction-associated steatotic liver disease related advanced fibrosis in diabetology: a prospective multi-center study.
Authors: Caussy Cyrielle , Vergès Bruno , Leleu Damien , Subtil Fabien , Abichou-Klich Amna , Hervieu Valérie , Milot Laurent , Ségrestin Bérénice , Rouland Alexia , Delaunay Dominique , Morcel Pierre , Hadjadj Samy , Primot Claire , Petit Jean-Michel , Charrière Sybil , Moulin Philippe , Levrero Massimo , Cariou Bertrand , Disse Emmanuel
Published: January 2025

Objective: Screening for advanced fibrosis (AF) due to metabolic dysfunction-associated steatotic liver disease (MASLD) is recommended in diabetology. This study aimed to compare the performance of non-invasive tests (NITs) and 2-step algorithms for detecting patients with high-risk AF requiring referral to hepatologists.

Research Design and Methods: A planned interim analysis of a prospective multi-center study including participants with type 2 diabetes and/or obesity and MASLD with comprehensive liver assessment including blood-based NITs, vibration-controlled transient elastography (VCTE) and two-dimensional shear-wave elastography (2D-SWE). AF risk stratification was determined by a composite criterion, including liver biopsy, magnetic resonance elastography, or VCTE ≥12 kPa depending on availability.

Results: Among 654 patients (87% with type 2 diabetes, 56% male, 74% with obesity), 17.6% had intermediate/high risk of AF, and 9.3% had high-risk of AF. The AUROCs [95% confidence interval] of NITs for high-risk AF detection were: FIB-4: 0.78 [0.72-0.84], FibroMeter®: 0.74: [0.66-0.83], Fibrotest®: 0.78 [0.72-0.85], ELF™: 0.82 [0.76-0.87], SWE: 0.84 [0.78-0.89]. Algorithms with FIB-4/VCTE showed a good diagnostic performance for referral of intermediate/high-risk AF in specialized care in hepatology. An alternative FIB-4/ELF strategy showed a high NPV (88-89%) and a lower PPV (39-46%) at a threshold of 9.8. The FIB-4/2D-SWE strategy had a NPV of 91% and a PPV of 58-62%. Age-adapted FIB-4 threshold resulted in lower NPV and PPV in all algorithms

Conclusion: The FIB-4/VCTE algorithm showed an excellent diagnostic performance demonstrating its applicability for routine screening in diabetology. ELF using an adapted low threshold at 9.8 may be used as alternative to VCTE.
In-hospital DIAbetes management by a diabetes TEam and insulin titration algorithms based on Continuous glucose monitoring or point-of-care glucose testing in patients with type 2 diabetes (DIATEC) – a randomised controlled trial
Authors: T. Olsen Mikkel , K. Klarskov Carina , H. Jensen Signe , M. Rasmussen Louise , Lindegaard Birgitte , A. Andersen Jonas , Gottlieb Hans , Lunding Suzanne , Pedersen-Bjergaard Ulrik , B. Hansen Katrine , L. Kristensen Peter
Published: January 2025

Objective: The DIATEC trial investigates the glycaemic and clinical effects of inpatient continuous glucose monitoring (CGM)-guided insulin titration by diabetes teams. Research design and methods: This two-centre trial randomised 166 non-intensive care unit patients with type 2 diabetes. Diabetes management was performed by regular staff, guided by diabetes teams using insulin titration algorithms based on either point-of-care glucose testing or CGM. The primary outcome was the difference in time in range (TIR) (3.9–10.0 mmol/l) between the two arms. Outcomes were assessed during hospitalisation. Results: The CGM-arm achieved a higher TIR (median, IQR) of 77.6% (24.4) vs 62.7% (31.5) in the POC-arm (p <.001). Time above range (TAR) >10.0 mmol/l was lower in the CGM-arm of (median, IQR) 21.1% (24.8) vs 36.5% (30.3) in the POC-arm (p=.001). Time below range (TBR) <3.9 mmol/l was reduced by CGM, with a relative difference to POC of 0.57 (95% CI 0.34–0.97) (p =.042). Prolonged hypoglycaemic events decreased (IRR 0.13, 95% CI 0.04–0.46) (p =.001), and the coefficient of variation (mean, SD) was lower in the CGM-arm of 25.4% (6.3) vs 28.0% (8.2) in the POC-arm (p =.024). Total insulin doses (mean, SD) were reduced in the CGM-arm with 24.1 IU/day (13.9) vs 29.3 IU/day (13.9) in the POC-arm (p =.049). A composite of complications was lower in the CGM-arm (IRR 0.76, 95% CI 0.59–0.98) (p=.032). Conclusions: In-hospital CGM increased TIR by 15%-points, mainly by reducing TAR. CGM also lowered TBR, glycaemic variability, prolonged hypoglycaemic events, insulin usage, and in-hospital complications.
Relapse detection in the Danish surveillance program of patients with clinical stage I seminoma: a nationwide study
Authors: Lindahl Niklas B. , Lauritsen Jakob , Wagner Thomas , Daugaard Gedske , Bandak Mikkel
Published: January 2025

Background and purpose: Active surveillance is a recommended management strategy for patients with clinical stage I (CSI) seminoma. This study aims to identify patterns of relapse detection methods in an unselected population-based cohort of CSI patients and provide evidence for a risk-adapted follow-up program.
Patients/materials and methods: A total of 924 patients with CSI seminoma were identified in the prospective Danish Testicular Cancer database. Retrospectively collected clinical data were used for descriptive analyses of patterns in detection methods. Additionally, we explored a risk-adapted surveillance approach based on recently identified risk factors for relapse, classifying patients into low- and non-low-risk groups.
Results: At 60 months, the 5-year cumulative relapse risk was 16%, with 146 relapses during surveillance. Relapses were detected by imaging alone in 71% of cases, imaging combined with elevated serum tumor markers (STMs) in 18%, isolated elevation of STMs in 8%, and by self-referral due to symptoms in 3%. No relapses were detected by abnormal findings at a physical examination. In total, 134 (92%) relapses were localized to retroperitoneal lymph nodes, primarily without additional spread. The 5-year relapse risk in patients with low risk of relapse was 9% compared to 28% in patients in the non-low-risk group.
Interpretation: This study highlights that the surveillance program can detect relapses at an early stage. Reduction of visits and omission of routine physical examinations can safely be considered for patients with a low risk of relapse, while further research is needed to optimize follow-up and treatment for patients at higher risk of relapse.
Personal Motivation and Satisfaction to School Leaders Among Elementary Teachers: Correlation and Regression Approach
Authors: Casinillo Leomarich F , Hungo Melbert , Cortes Jessica , Bijo S. Anand
Published: January 2025

Many teachers experience decreased motivation and dissatisfaction due to a lack of support from school leaders, which ultimately impacts the quality of teaching and learning. This study analyzes the relationship between teachers' motivation and satisfaction with school leadership using correlational and regression approaches. This study used a quantitative descriptive-correlational research design. Sixty-one primary school teachers participated in this study as respondents, who were selected through simple random sampling. Data were collected using a validated research questionnaire consisting of motivation and satisfaction. The research instrument was subjected to a reliability test with Cronbach's alpha to ensure consistency using the instrument in the form of a questionnaire sheet. Data analysis used descriptive statistics, Pearson product-moment correlation, Spearman rho correlation, chi-square test, ordinary least square (OLS) regression, and logit regression to determine the strength and direction of the relationship between variables. The regression results further showed that increased satisfaction with school leadership predicted higher levels of teacher motivation. It is concluded that improving school leadership practices can significantly contribute to increased teacher motivation, improving teaching quality and overall school performance. Therefore, it is recommended that school leaders receive targeted training to develop leadership skills that can increase teacher satisfaction and motivation.
Family Socialization, Teacher Example, and Social Heterogeneity on the Diversity of Characters in the Global Profile of Pancasila Students
Authors: Yeni Susanti  , Ravik Karsidi  , Ahmad Zuber
Published: January 2025

This research was motivated by the development of the Merdeka Curriculum, whose implementation also focused on developing the character of the Pancasila Student Profile. One of the dimensions is the development of the character of Global Diversity, namely the habit of preserving noble culture, identity, locality and developing an open attitude in interactions with other cultures both on a national and global scale. The character of global diversity is a habit that is instilled from the family environment, school to society. In fact, there are still many conflicts caused by feelings of intolerance and discrimination, parents who only focus on their children's external needs and teachers who are unable to be role models. This research examines the influence between the intensity of family socialization, the level of teacher example and social heterogeneity on the level of global diversity character of Pancasila student profiles using a quantitative approach. This research is research with a quantitative approach, using a survey method with an explanatory research type. The results of this research show that the variables tested show a high category. Based on the results of the t test, it shows that there is a significant influence between the three dependent variables on the independent variables. The implication of this research is that teachers not only teach academic material, but also provide real examples of Pancasila values, such as integrity, cooperation and respect for differences.
Students' Readiness on Practical Learning in Mechanical Engineering Education: Post-Pandemic Survey
Authors: Suwondo Hermansah  , Sutiman  , Farid Mutohhari  , Alfat Khaharsyah
Published: January 2025

The post-pandemic era of COVID-19 still leaves crucial problems for vocational education (VE), including mechanical engineering education (MEE). Practical learning readiness (PLR), which includes the dimensions of readiness for supporting knowledge, physical and psychological conditions in students, is a fundamental problem that must be solved through systematic mapping. Therefore, this research aims to measure the level of readiness in these three dimensions. In addition, we also examine the differences between dimensions and indicators and test the determination in constructing the PLR to determine systematic problem-solving. The survey was conducted on 386 MEE students, but the final number was 339, considering that 47 of them did not have good data rationale level criteria. The results of the descriptive analysis confirmed that the psychological condition and supporting knowledge had a low level, while the physical condition had a high level. The results of the comparison test show that the three are generally not significantly different, although there are notes in several indicators. Although all dimensions contribute significantly to constructing PLR, psychological conditions contribute the highest. This indicates that low psychological conditions are the first step for VE to suffer. Furthermore, several notes related to the decrease in knowledge-supporting practice are also the second effort that MEE must make in boosting PLR in its students.