bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and epidemiological characteristics of chickenpox in children aged 0–17 in Barnaul
Authors: Peredelskaya E. A. , Safyanova T. V. , Druchanov M. M.
Published: March 2021

Introduction. Chickenpox is one of the most common infectious diseases in childhood. It is considered a benign disease, but both children and adults can lead to the development of serious complications.

Purpose: to study the epidemiological and clinical features of chickenpox in children aged 0–17 years, hospitalized in the Krai government-owned publicy funded health care institution “City clinical hospital No. 11, Barnaul”, for the period 2008–2018.

Materials and methods. The materials of the study were data from statistical reporting forms No. 2 of the Federal state statistical observation “Information on infectious and parasitic diseases” in Barnaul for 2008–2018, and medical archive documentation of the children’s infectious diseases Department of the Krai government-owned publicy funded health care institution “City clinical hospital No. 11, Barnaul” for the same period. Data processing was performed using calculation of intensive and extensive indicators, calculation of the arithmetic mean (X) and standard error of the average (m). Calculations were made using the STATISTICA-10 program.

Results. The incidence of chickenpox is consistently high, and children aged 3 to 6 years dominated the structure of hospitalized patients with the diagnosis of «chickenpox». All patients were not vaccinated against this infection. Patients developed complications due to the layering of secondary bacterial flora. Summary. Chickenpox is an infectious disease that can be severe, especially in patients with a heavy premorbid background. There is a tendency to” grow up” the infection, which emphasizes the need to discuss specific prevention of the disease.
Epidemiological and pharmacoeconomic aspects of HIV infection in military
Authors: Bulankov Yu. I. , Bulygin M. A. , Bespalov A. V. , Zhdanov K. V. , Murachev A. A. , Ivanov K. S. , Lyashenko Yu. I.
Published: March 2021

The goals of the research are to determine the latent morbidity and financial losses of the Russian Ministry of Defense due to the dismissal of service members with HIV infection at symptomatic stages; to establish the supposed clinical and pharmacoeconomic effectiveness of the early detection and treatment of service members.

The materials compile 379 case histories of patients of the only specialized department for HIV-positive military personnel in the Armed Forces for 2017–2019, as well as various reporting forms. The study uses the following methods for the analysis: Markov chains are employed to calculate QALYs (Quality Adjusted Life Years), “cost-effectiveness”, and “willingness to pay”. The research compares two competitive models: “Current Situation” - without the introduction of algorithms for early detection and treatment of HIV infection, and “Prognosis” - with the introduction of these algorithms.

The following results are obtained: implementing a mandatory triennial screening for HIV-antibodies among military personnel allows to raise the detection of HIV-positive military personnel in the early stages of the disease by 55%. At the same time, early administered antiretroviral therapy prevents the progression of HIV infection, while the number of military personnel who have reached symptomatic stages of HIV infection and the number of deaths decreases by 35,6% and 80,2% (six-fold), respectively. The economic effectiveness of these measures includes a reduced cost of treatment and an increased length of military service. The sensitivity analysis of the method shows that the proposed measures remain pharmacoeconomically highly effective with a wide variability of the initial data.

Conclusion. The results of the study demonstrate that a significant improvement of the epidemiological situation in the field of HIV infection in the Armed Forces is achievable at very low economic costs. With the full implementation of the proposed measures, the cohort of military personnel of the Armed Forces is able to achieve the World Health Organization’s “90-90-90”criteria of in 3–5 years.
Arguing for classical critical theory
Authors: Rasmussen David
Published: March 2021

In my view, making the case for a specific interpretation of Critical Theory
is problematic.1 Although the term has a prestigious origin stemming from
Horkheimer?s 1937 paper, Traditional and Critical Theory,2 given during his
term as Director of the Institute for Social Research at Frankfurt
University and generating the enthusiasm of its members, the term and the
movement associated would be defined and radically redefined not only by
subsequent generations but by its very author. One of the merits of the book
under discussion is that even before the first chapter an ?Interlude? is
presented entitled Arguing for Classical Critical Theory signifying to the
reader that Horkheimer got it right when he defined the subject and that it
is possible to return to that particular definition after 83 years. This
paper challenges Professor S?rensen?s claims for the restoration of
classical Critical Theory on three levels: the scientific, the historical
and the political level.
Theory caught up in dialectics: Some reflections on Asger Sørensen’s capitalism, alienation and critique
Authors: Ivkovic Marjan , Prodanovic Srdjan , Urosevic Milan
Published: March 2021

This paper presents three interconnected examinations of Asger S?rensen?s
arguments in Capitalism, Alienation and Critique, which thematize S?rensen?s
overarching understanding of the relationship between theory and practice:
his general methodological perspective on critical theory, its distinctive
epistemology and its anchoring in the empirical world. The paper authors
each try to push S?rensen on these crucial points by considering how
S?rensen?s variant of critical theory actually operates, scrutinizing in
more detail the particular relationship between the ?experience of
injustice?, which for S?rensen constitutes the empirical foothold for
critical theory, and the theoretical diagnosis of social reality which the
critical theorist should formulate against the backdrop of this experience.
Dialectics as immanent critique. Or, dialectics as both ontology and epistemology with a practical intention
Authors: Shijun Tong
Published: March 2021

This response to Asger S?rensen?s paper From Ontology to Epistemology: Tong,
Mao and Hegel is made on the basis of a reflection on the author?s
intellectual development with special reference to the idea of ?dialectics?.
This development is mainly composed of three periods, in which the author
formed his strong antipathy toward dialectics as a mere tool of power (in
the 1970s), learnt to understand the importance of ?dialogical logic? in
providing conceptual tools for human knowledge of a type of reality which is
both objective and subjective - human practices (in the 1980s) - and
attempted to understand the ?dialectics of rationalization? by integrating
?dialectics? in the Western tradition of Critical Theory with the Chinese
tradition of ?dialectics? systematically interpreted by Feng Qi (1915-1995)
since the 1990s.
On murderous silence
Authors: Crépon Marc
Published: March 2021

The paper focuses on violence, claiming that it is not action, but silence
and inaction that become ?murderous?, given that we are forced into a
permanent and impossible process of choosing between responsibility for the
other and the possibility of responding to a call for help. Still, this
position is not final and the author offers certain alternative strategies,
such as rebellion, goodness, critique and shame.
Kant on just war and international order
Authors: Milicic Nenad
Published: March 2021

Kant?s legal and political philosophy is essential for understanding and
advancing international order. The article aims to posit arguments that
confront the claims that Kant was just war theorist. Since that is the most
opposed part of Kant?s political philosophy, mostly due to the misleading
interpretation of his argumentation, the author presents Kant?s standpoint
on the matters of just war and international order and discusses potential
ambiguities between Kant?s and his critics? theories. Furthermore, the
consequences of opponents? arguments considering states of states, world
republic and cosmopolitan democracy in contemporary political philosophy are
debated. Finally, the possibility of consent between the three model
solutions which are arising from the contemporary international order theory
and Kant?s position are compared and analysed.
The natural operators similar to the twisted courant bracket on couples of vector fields and p-forms
Authors: Mikulski Włodzimierz
Published: March 2021

Given natural numbers m and p with m ? p + 2 ? 3, all Mfm-natural operators A
sending closed (p+2)-forms H on m-manifolds M into R-bilinear operators AH
transforming pairs of couples of vector fields and p-forms on M into couples
of vector fields and p-forms on M are found. If m ? p + 2 ? 3, all
Mfm-natural operators A (as above) such that AH satisfies the Jacobi
identity in Leibniz form are extracted, and that the twisted Courant bracket
[-,-]H is the unique Mfm-natural operator AH (as above) satisfying the
Jacobi identity in Leibniz form and some normalization condition is deduced.
Existence of the solution to second order differential equation through fixed point results for nonlinear F-contractions involving w0-distance
Authors: Iqbal Iram , Rizwan Muhammad
Published: March 2021

In the present paper, the aim is to obtain some new fixed point theorems for
nonlinear F-contractions involving generalized distance to prove the
existence of solution to second order differential equation related to
conversion of solar energy to electrical energy. Non-trivial examples are
also presented, to illustrate the obtained results and to show that new
results are proper generalization of recently appeared results in the
literature.
Iterative schemes induced by block splittings for solving absolute value equations
Authors: Shams Nafiseh , Jahromi Alireza Fakharzadeh , Beik Fatemeh
Published: March 2021

In this paper, we develop the idea of constructing iterative methods based on
block splittings (BBS) to solve absolute value equations. The class of BBS
methods incorporates the well-known Picard iterative method as a special
case. Convergence properties of mentioned schemes are proved under some
sufficient conditions. Numerical experiments are examined to compare the
performance of the iterative schemes of BBS-type with some of existing
approaches in the literature such as generalized Newton and Picard(-HSS)
iterative methods.
Ricci curvature on warped product submanifolds of Sasakian-space-forms
Authors: Mandal Pradip , Pal Tanumoy , Hui Shyamal
Published: March 2021

The paper deals with the study of Ricci curvature on warped product pointwise
bi-slant submanifolds of Sasakian-space-form. We obtained some inequalities
for such submanifold involving intrinsic invariant, namely the Ricci
curvature invariant and extrinsic invariant, namely the squared mean
curvature invariant. Some relations of Hamiltonian, Lagrangian and Hessian
tensor of warping function are studied here.
On statistical and strong convergence with respect to a modulus function and a power series method
Authors: Belen Cemal , Yıldırım Mustafa , Sümbül Canan
Published: March 2021

This paper introduces and focuses on two pairs of concepts in two main
sections. The first section aims to examine the relation between the
concepts of strong Jp-convergence with respect to a modulus function f and
Jp-statistical convergence, where Jp is a power series method. The second
section introduces the notions of f-Jp-statistical convergence and f
-strong Jp-convergence and discusses some possible relations among them.
Generalizations of second submodules
Authors: Çeken Gezen , Tekir Ünsal , Koç Suat , Kelleqi Ajlin
Published: March 2021

In this paper, we introduce and study some new generalizations of second
submodules via a function ? on the set of all submodules of a module. Let R
be a ring with non-zero identity, M be an R-module and ? : S(M)? S(M) be
a function where S(M) is the set of all submodules of M. A non-zero
submodule N of M is said to be a ?-second submodule if, for any element a of
R and a submodule K of M, aN ? K and a?(N) ?/K imply either N ? K or a ?
annR(N). Let n ? 2 be an integer and ?n : S(M) ? S(M) be the function
defined by ?n(L) = (L :M annR(L)n-1) for every L?S(M). Then a ?n-second
submodule of M is said to be an n-almost second submodule of M. We determine
various algebraic properties of these submodules and investigate their
relationships with other known submodule classes such as second, prime and
semisimple submodules. We study the structure of n-almost second submodules
of modules over ZPI-rings and Dedekind domains. We also give some
characterizations of modules and submodules by using n-almost second
submodules.
Lineamientos para la conservación de la conectividad a través de redes y corredores ecológicos
Authors: Hilty Jodi , Worboys Graeme L. , Keeley Annika , Woodley Stephen , Lausche Barbara J. , Locke Harvey , Carr Mark , Pulsford Ian , Pittock Jamie , White Wilson J. , Theobald David M. , Levine Jessica , Reuling Melly , Watson James E.M. , Ament Rob , Groves Craig , Tabor Gary M.
Published: March 2021

En ecosistemas terrestres, dulceacuícolas y marinos, los corredores ecológicos son una designación de conservación necesaria para asegurar la salud de los ecosistemas. Los corredores son elementos fundamentales de las redes ecológicas para la conservación y complementan los objetivos de las áreas protegidas y OMEC al conectar estos hábitats con otras áreas naturales intactas. Estos lineamientos responden a la creciente demanda por la conectividad que han manifestado académicos, tomadores de decisiones y profesionales de la conservación. Los ecosistemas bien conectados apoyan una serie de funciones ecológicas, incluyendo la migración, ciclos de agua y de nutrientes, polinización, dispersión de semillas, seguridad alimentaria, resiliencia frente al clima y resistencia a enfermedades. Estos lineamientos ofrecen orientación sobre cómo conservar los valores de la conectividad en diferentes contextos de la conservación de forma consistente y medible. Los 25 estudios de caso de estos lineamientos ofrecen ejemplos y buenas prácticas que muestran algunos enfoques que pueden asegurar la conectividad ecológica entre diferentes ecosistemas y especies a diferentes escalas espaciales y temporales. Para asegurar la integración y aceleración de la adopción de las medidas de conservación de la conectividad con el fin de amortiguar y promover la adaptación al cambio climático, es necesario enfatizar las capacidades humanas y técnicas.
Teacher Management in Early Childhood Education
Authors: Dewi Dita
Published: March 2021

This study aims to describe the planning, recruitment, coaching, and development at Surya Ceria Aisyiyah kindergarten, Cangakan, Karanganyar. This research is a qualitative descriptive study. Data collection uses observation techniques, interviews, and documentation. Test the validity of the data using technical triangulation and source triangulation. Data analysis using the model of Miles and Huberman namely the reduction stage, the stage of data presentation, and drawing conclusions.       The results of his research are (1) Planning in Surya Ceria Aisyiyah PAUD using job analysis and job analysis. (2) Recruitment of teachers in kindergarten Surya Ceria Aisyiyah, namely forming a committee for the recruitment of prospective new educators, announcements, administrative selection. The selection process for applicants in kindergarten Surya Ceria Aisyiyah includes administrative selection, written test, interview test, microteaching test. after the test ends, the overall test results will be discussed and determined which ones are accepted and rejected. Applicants who pass the selection face the school principal to be given directions related to the work contract and salary; (3) Guidance and development of educators through the identification of educator needs with evaluation methods. Forms of coaching and development in kindergarten Surya Ceria Aisyiyah Cangakan Karanganyar, namely supervision of school principals, seminars, workshops, training, In House Training, organization, training, visits, and comparative studies, further education.
The Effect of Quality Kindergarten Services
Authors: Badriyah Nurul
Published: March 2021

Early Childhood Education Institutions have been spread in various regions because they see the importance of education, one of which is in the district of Colomadu. At this time, Early Childhood Education institutions are trying to improve their quality in order to attract parents' interest in order to increase parental satisfaction. The purpose of this study was to determine the quality of kindergarten institutions and the level of satisfaction of parents in the district of Colomadu. Subjects in this study were 575 parents of kindergarten institutions in Subdistrict of Colomadu. Sampling using a random propotional sample methodso as many as 73 parents obtained parents. Data collection techniques used questionnaire method, documentation. Data collected were analyzed using descriptive analysis and simple regression analysis. Based on the calculation of simple linear regression coefficient test data obtained (R2 )) equal to 0.174 which implies that the influence of the independent variable (TK service quality) on the dependent variable (the level of parental satisfaction) is 17.4% while the remaining 83.6% is influenced by other factors. And obtained t count 3.864 and obtained value of t table = 1.993 with a significance level of 0.05, then t arithmetic = 3.864 t table = 1.993 so that H0 is rejected and Ha is accepted. Means it can be concluded that there is a significant influence (significance) between the quality of kindergarten services on the level of satisfaction of parents in the Colomadu District 2018/2019.
Relationship between Teacher Academic Qualification with Learning Management in Early Childhood
Authors: Wulandari Tika
Published: March 2021

Research on the Influence Motivation Study and Environmental Learning Against Achievement Learning Students showed that There is the influence of positive motivation to learn and environmental learn to achievement learn student . case is shown by the analysis of regression linear multiple , that the value of t count motivation to learn at 2.476 with significance 0.016 0.05 then H0 is accepted , and environmental learning has value t arithmetic amounted to 4.977 with significance 0.000 0.05 then H0 is accepted . While the value of F arithmetic amounted to 53.069, and the value of R square of 0.639 (63.9%). Relative contribution to the variable of learning motivation give a donation of 31% and variable environment study provides donations relatively amounted to 69%, the total contribution relative of 100%. Donations effective at variable motivation to learn by 19.81% and environment study by 63.91%, which means that the motivation to learn and environment study are jointly provide donations effectively amounted to 63.91% against the achievement of learning , and 36.09% of other variables not examined .
Use of Manipulative Media as A Stimulation Of Ability To Understand The Concept of Early Children's Age
Authors: Palupi Agustina Nur
Published: March 2021

Every child has the right and needs for stimulation of his development. One of them is cognitive. Aspects of cognitive development can be stimulated through mathematics learning. But children can find it difficult to understand mathematical concepts because reasoning and logic are needed, whereas mathematical concepts are not concrete. For this reason, concrete media need to be used to demonstrate or illustrate the concept, the media are manipulative. The purpose of this study is to analyze articles and documents resulting from research on the use of manipulative media as a stimulation of the ability to recognize the concept of child numbers. Method: This research uses a literature review method. There are criteria in searching journals so that 20 journals are found to be analyzed based on population, sample, variables, data analysis, type of research design, and research results. Results and discussion: Literature review shows that the use of manipulative media in early childhood education varies greatly in terms of media material, its play, and its effectiveness. The manipulative media in question such as grain media, number blocks, clock puzzles, container marbles, picture cards, congklak numbers cards, numbers fishing games, and others. While the ability to recognize the concept of numbers in question such as the meaning of the symbol number of concepts a lot a little, counting, and others. Statistical analysis shows the application of manipulative media can stimulate the ability to recognize the concept of numbers in children, increase the activities of children and teachers, and found the response of children who are happy with the use of manipulative media. Conclusion: Manipulative media can stimulate the ability to recognize the concept of child numbers.
The Influence of Democratic Parenting Patterns to The Creativity of Early Ages
Authors: Istisaroh Desta Alicha
Published: March 2021

Children's creativity is the development of children's behavior to express themselves freely, children can imagine and explore what they do. To increase children's creativity is supported by parenting applied by parents. In addition to parents and family, external factors that affect children's creativity are the school environment and the surrounding community and the parenting patterns applied by parents. Parenting patterns include love and affection, and a good relationship between parents and children, the attitude parents show to children, and various rules created by parents to control children's behavior.
Relationship between The Education of Parents and Democratic Update Patterns To The Social Development of Early Ages
Authors: Juarus Ilma Rhosma
Published: March 2021

From the results that have been examined, it can be concluded that there is a relevant relationship between the educational background of parents and democratic parenting towards the social development of early childhood in the village of Bandar Magetan. this incident can be seen from the magnitude of r square of 33.6% can be interpreted the higher level of parental education resulted in parents increasingly understanding good parenting to help social development of young children.From the research also can be underlined the existence of democratic parenting can be influenced by the age of parents and educational background in order to support the social development of children.
Learning Management, Covid-19 pandemic
Authors: Rifngatin Ika
Published: March 2021

The purpose of this research is to describe 1) the learning planning during the Covid-19 pandemic in RA Amanah Ummah 8 is correct, 2) the implementation of learning during the Covid-19 pandemic in RA Amanah Ummah 8 is correct, 3) Evaluation of learning during the Covid-19 pandemic at RA Amanah Ummah 8 right.This research is a qualitative descriptive study. Data collection was carried out through observation, interviews, and documentation. The validity of the data in this study used triangulation of sources and triangulation of techniques. Data analysis techniques in this study used data reduction, data presentation and drawing conclusions. The results of this study indicate that: (1) lesson plans prepared during the pandemic use RPPM. (2) the implementation of learning during the Covid-19 pandemic uses 2 learning models, namely through parents and home visit. (3) evaluation of learning during the Covid-19 pandemic using weekly evaluations.
Osallistumisen muodot, tilat ja mahdollisuudet tiedon yhteistuottamisessa: Näkökulmia osallistuvasta budjetoinnista ja lähiön yhteiskehittämisestä
Authors: Lehtonen Pauliina , Tuurnas Sanna
Published: March 2021

Tarkastelemme artikkelissa tiedon yhteistuottamista asuinalueiden kehittämisessä. Asuinalueiden kehittämishankkeet tuovat yhteen erilaisia toimintakulttuureita, toimijoita ja tiedon muotoja, mikä synnyttää tarpeen tarkastella, millaisen tiedon tai kenen asiantuntijuuden pohjalta asuinalueita kehitetään ja millaisia menetelmiä ja valmiuksia tämä edellyttää. Tarkastelemme kahdessa tamperelaisessa lähiökehittämishankkeessa, miten tietoa asuinaluekehityksessä yhteistuotetaan. Tesoman osallistuvan budjetoinnin ja Annala-Kaukajärven yhteiskehittämishankkeen aineisto on kerätty toimintatutkimuksella ja havainnoimalla. Jäsennämme tiedon yhteistuottamisprosessia teema-areenan käsitteellä teeman luonnetta ja kontekstia, toimijoita, vuorovaikutuksen paikkoja ja keskustelun kulkua analysoimalla. Tiedon yhteistuottaminen edellyttää organisaatiolta epävarmuuden sietoa ja yhteistuottamisen ymmärtämistä kahdensuuntaisena vuorovaikutusprosessina. Se vaatii resursseja, vastuiden määrittelyä ja strategista suunnittelua. Organisaatioiden sisäiset vuorovaikutus- ja viestintäprosessit ja tiedon yhteistuotannosta vastaavien ammattilaisten vuorovaikutustaidot vaikuttavat prosessin onnistumiseen.
Kun tietoa mitataan euroissa: Tulosjulkistukset tiedosta neuvottelemisen areenoina
Authors: Hirsto Heidi , Koskela Merja , Penttinen Kaisa
Published: March 2021

Sijoittajaviestintä on vahvasti säännelty organisaatioviestinnän alue, jossa informaatiolla on usein välittömiä taloudellisia seurauksia. Sääntelyllä pyritään edistämään erityisesti informaation saatavuutta, läpinäkyvyyttä ja tasapuolisuutta. Tässä artikkelissa tarkastellaan tulosjulkistustilaisuuksia, joissa pörssiyhtiöt julkistavat osavuosituloksensa ja analyytikot esittävät kysymyksiä yritysjohdolle. Tavoitteena on lisätä ymmärrystä siitä, millaisia tiedosta neuvottelemisen käytänteitä tulosjulkistustilaisuuksissa ilmenee, sekä pohtia, miten niiden kautta voidaan osaltaan tukea tai ehkäistä tasapuolisuuden vaatimuksen toteutumista. Tarkastelun kohteena on rajankäynti informaation ja tiedon, julkisen ja salatun sekä eksplisiittisen ja implisiittisen välillä. Aineistona on kuuden tulosjulkistustilaisuuden kysymys – vastaus-osiot. Niiden diskurssianalyyttinen tarkastelu tuo esiin tulosjulkistustilaisuudelle ominaisia salaamisen ja läpinäkyvyyden käytäntöjä, jotka liittyvät tilanteen julkiseen ja vuorovaikutteiseen luonteeseen vahvasti normitetussa ympäristössä. Siinä missä läpinäkyvyyden on nähty tuottavan uusia salaamisen käytäntöjä, tiukat salaamisen vaatimukset näyttävät puolestaan johtavan uusiin läpinäkyvyyden käytäntöihin, jotka mahdollistavat esimerkiksi keskeneräisen ja jäsentymättömän informaation esiin nostamisen. Analyysi tuo esiin, että keskustelussa rakentuvan tiedon läpinäkyvyys ja tasapuolisuus on osittaista ja näkökulmasidonnaista ja sitä kautta taloudellisen tiedon mikropolitiikan tulosta.
PATHOHISTOLOGICAL PECULIARITIES OF THE FORMATION OF IRON OVERLOAD SYNDROME IN PATIENTS WITH STEATOHEPATITIS DEPENDING ON ITS ETIOLOGY
Authors: Antofiichuk T.M. , Davydenko I.S. , Khukhlina O.S. , Antofiichuk N.P. , Haidychuk V.S.
Published: March 2021

The aim – to study some histopathological features of the iron overload syndromeformation in patients suffering from steatohepatitis depending on its etiology.Material and methods. Liver biopsies were analyzed in 30 patients with nonalcoholicsteatohepatitis (NASH) and 20 patients with alcoholic steatohepatitis (ASH). Themorphological examination of the liver was carried out according to the standardmethods. The histopathological features of the liver were established on the basis ofthe method of staining with hematoxylin and eosin, with the confirmation, in case ofnecessity, by the histochemical methods - staining for fat (the method with Sudan-III) andcollagen fibers (the method with chromotropic-water blue according to N.Z Slinchenko).Microspectrophotometric studies were conducted using a cytological analyzer withsoftware "VideoTest - Size 5.0" (2000).Results. The same regularities for both trivalent iron and twovalent iron were revealed asa whole in the liver cells at histological investigations, that is in ASH the optical densityis at the average 1.3 (p<0.05) times higher than in NASH. The staining on trivalent ironis less intensive, than on the twovalent iron. There is probable iron overload syndrome inthe alcoholic steatohepatitis patients with increased uptake of it both 2+- and 3+- valentforms in the liver cells – reticuloendotheliocytes and hepatocytesConclusions. Iron overload syndrome with increased uptake of it for both 2+- and3+-valent takes place in the liver cells – endotheliocytes and hepatocytes – in patientswith alcoholic steatohepatitis. At alcoholic steatohepatitis the optical density withhistochemical staining on iron 2+ in reticuloendotheliocytes of the liver is 1.2 times andin hepatocytes – 1.3 times higher than at non-alcoholic steatohepatitis irrespective ofthe presence or absence of anemia. At alcoholic steatohepatitis the optical density ofhistochemical iron staining 3+ in reticuloendotheliocytes of the liver and hepatocytesis 1.3 times higher than in non-alcoholic steatohepatitis, and is irrespective of anemiapresence as well.
EVALUATION OF EFFECTIVENESS OF COMPREHENSIVE TREATMENT OF DUODENAL ULCER IN CHILDREN
Authors: Sorokman T.V. , Cherney N.Ya.
Published: March 2021

In the structure of pathology of the digestive organs 1.7–16% constitute peptic ulcerdisease, which in 90% of cases is associated with H.pylori infection.The aim is to evaluate the effectiveness of comprehensive treatment of duodenal ulcer inchildren.Material and methods: The study included 60 children at the age of 10 -18 years withHelicobacter pylori-associated duodenal ulcer (DU), who were divided into three groupsof 20 people depending on the treatment regimen (protocol, including the donor of nitrogen monoxide and capillary stabilizing preparation).Results. Complex therapy of the disease in children provides faster positive dynamics ofclinical and endoscopic symptoms, increases the frequency of eradication of Helicobacterpylori, the relative risk of recurrence will decrease by 0.57 times when included in thetreatment regimen of nitrogen oxide donor and 0.66 times when used along with theprotocol scheme of the donor nitrogen oxide and capillarotropic drug.Conclusion. Comprehensive treatment of DU provides more stable results of treatmentand decreases the disease recurrences both in the early and late stages of observation.
SOME DISCUSSION ISSUES OF THE HYPOTHYROIDISM PROBLEM
Authors: Lіаshuk P.M. , Lіаshuk R.P. , Skhodnуtskуi I.V.
Published: March 2021

The notion “subclinical hypothyroidism”, its significance in the genesis of metabolismdisorders, debatable approaches to the treatment as well as the role of the thyroidgland hypofunction in pathogenesis of the menstrual cycle disorders and infertility onthe example of the own clinical observation is given in the article.Objective – to designate the criteria for diagnosis and approaches to the treatmentof subclinical hypothyroidism, as well as to confirm the role of the manifestedhypothyroidism in the pathogenesis of the reproductive function disorders in women.Conclusions. 1. The thyroid gland hypofunction plays a significant role in the genesisof metabolic changes and development of the menstrual cycle disorders, galactorrheaand infertility. 2. The problem of hypothyroidism in general and, subclinicalhypothyroidism, in particular, requires further study in order to reduce the risk ofmetabolic diseases development.
FIBRIN ADHESIVES IN PROTECTION OF DIGESTIVE TRACT ANASTOMOSES (REVIEW OF FOREIGN LITERATURE)
Authors: Senyutovych R.V. , Ivashchuk О.І. , Bodyaka V.Yu. , Chuprоvska Yu.Ya. , Malyshevsky I.O. , Kravchuk С.Ю. , Shulgina V.V. , Halaturnyk I.B.
Published: March 2021

Data of experimental and clinical studies concerning fibrin adhesives’ use for theprotection of anastomoses of the gastrointestinal tract are submitted in the article.Definite data have not been obtained.Objective. The purpose of this study was to review literature on the protection ofanastomoses of the digestive system by fibrin adhesives. The study was conductedaccording to the Internet data.Conclusion. The given data testify that anastomoses strengthening with fibrin adhesivescan be effective in bariatric surgery. The majority investigations, preferably on rats,are an experimental research. It is premature to give recommendations concerningapplication of fibrin adhesives to strengthen other types of anastomoses. Fibrin adhesives’investigations in strengthening gastrointestinal tract anastomoses represent a perspectivedirection of up-to-date surgery. Significant achievements should to be expected.
CAUSATIVE-INVESTIGATORY RELATIONSHIPS BETWEEN BOWELS MICROBIOTA AND CLINICAL COURSE OF ISCHEMIA-REPERFUSION DAMAGE OF THE BRAIN
Authors: Tkachuk S.S. , Povar M.A. , Shtefaniuk V.I. , Tkachuk O.V.
Published: March 2021

The purpose – to carry out the analysis of the current data concerning relationships inthe “bowels microbiota-brain” system at ischemia-reperfusion damages of the brain.Conclusions.1. The analysis of the literature data testify to the views discrepancy, existing today, on therole of the bowels dysbacteriosis (neuroprotective or neurodegenerative) in the clinicalcourse of ischemic damages of the brain.2. Numerous experimental investigations substantiated the bowels microbiota role:homeostasis derangements of T-cells, which have the determined role in the secondaryneuroinflammation following cerebral ischemia; in the ratio change of their subpopulationsTreg-Th17 and migration of the bowels lymphocytes into the ischemic brain.
PERIPARTUM CARDIOMYOPATHY – A CLINICAL CASE
Authors: Rusnak І.Т. , Tashchuk V.K. , Slyvka N.O. , Kulachek V.T. , Kulachek Y.V.
Published: March 2021

This article presents a clinical case of peripartum cardiomyopathy in a 21-year-oldpatient with a gestational age of 32 weeks, accompanied by clinical manifestationsof heart failure and Lown-Ganong-Levine (LGL) syndrome. The patient underwentlaboratory and instrumental examinations, including echocardiography and Holtermonitoring. Thyrotoxic cardiomyopathy was ruled out in the process of differentialdiagnosis. The final diagnosis and management of the patient were determinedafter consultation with the State Institution "Institute of Pediatrics, Obstetrics andGynecology, named after Academician O.M. Lukyanova, of the National Academy ofMedical Sciences of Ukraine". Medical treatment significantly improved the patient'scondition and vaginal delivery went without complications. Manifestations of theperipartum cardiomyopathy gradually regressed and completely disappeared 6 monthsafter delivery.This case indicates the importance of timely diagnosis of peripartum cardiomyopathyfor a positive prognosis of patients.
FEATURES OF APONEUROSIS PATHOMORPHOLOGICAL CHANGES IN PATIENTS WITH EVENTRATION
Authors: Voitiv Ya.Yu , Dyadyk O.O.
Published: March 2021

Objective – to improve the treatment results of patients with eventration by determiningthe role of undifferentiated connective tissue dysplasia in the development of thiscomplication.Material and methods. The object of the study comprises 33 patients with eventrationwho were treated in the department of thoracoabdominal surgery of Shalimov NationalInstitute of Surgery and Transplantology during 2017-2020.Results. At complex pathomorphological research of aponeurosis fragments similarmorphological changes have been revealed in groups of patients with phenotypic signsof undifferentiated connective tissue dysplasia and eventration. Immunohistochemicalexamination of tissues with monoclonal antibodies to α-SMA revealed uneven, focalexpression in smooth muscle differentiation cells and fibroblasts in both groups. In thestudies with monoclonal antibodies to Collagen IV, moderate positive expression in thebasement membrane of the blood vessels, in smooth muscle cells of the muscular layerof the vascular wall, in areas of the connective tissue was observed, that is a sign ofpathological remodeling of the connective tissue.Conclusions. Similar pathomorphological changes of the aponeurosis in groups withphenotypic signs of undifferentiated connective tissue dysplasia and post-operativeeventration confirm the role of the connective tissue pathology in the development of thiscomplication.
MEDICAL AND SOCIAL JUSTIFICATION OF MULTI-FACTOR PREVENTION OF MAJOR NONCOMMUNICABLE DISEASES
Authors: Vlasyk L.Y.
Published: March 2021

Purpose – to substantiate and propose a model of multi-factor prevention of majornoncommunicable diseases (NCDs) at the level of primary health care (PHC).Material and methods. The analysis of the results of a cross-sectional sociologicalstudy (N=1252); copying from the medical documentation of inpatients (n=1543) andtheir survey data (n=57) were the materials and basis for the development of the model.Content analysis, conceptual modelling method, and statistical methods (PIVOT, χ2test,step-by-step logistic regression analysis) were used.Results. The prevalence of combined pathology of NCDs was determined on the exampleof hospitalized patients. The importance of taking into account the age and results ofthe primary screening in the formation of the COPD risk group and the possibility ofsupplementing it with an assessment of the risk of fatal complications of cardiovasculardiseases on the SCORE scale is proved. Features of prevalence and combination ofrisk factors (RF) and the major NCDs among the economically active population arerevealed. It was found that with the same targeted preventive consultation of patients byPHC and specialized medical care doctors, the effectiveness of interventions significantlyincreases. The key to the high effectiveness of prevention is proved to be coordinatedcooperation between medical professionals at different levels of medical care and patientand their families.Conclusions. The proposed model of multi-factor prevention of major NCDs is based ona patient-oriented approach, taking into account the combined RF and major NCDs. Theprinciple of an integrated approach and the complexity of interventions is ensured bylayering all types of prevention provided by PHC in cooperation with specialized medicalcare and the public health service.
PREVALENCE OF ENDONASAL PATHOLOGY IN PATIENTS WITH CHRONIC DACRYOCYSTITIS AND PECULIARITIES OF SURGICAL TREATMENT
Authors: Minaiev О.О.
Published: March 2021

Purpose – to study the prevalence of endonasal pathology in patients with chronicdacryocystitis (CD) and to justify the expediency of simultaneous operations in suchpatients.Material and methods. The study included 109 patients with CD, who were examinedand operated on in 2004-2014 at the Department of Otorhinolaryngology Faculty ofInternship and Postgraduate Education "Donetsk National Medical University of theMinistry of Health of Ukraine". Examination of patients included consultation with anophthalmologist, lavage of the lacrimal ducts, endoscopy of the nasal cavity, computedtomography. All patients underwent tearing by performing endonasal endoscopicdacryocystorhinostomy (EEDCR).Results. Endonasal pathology was detected in 85.3% of patients: curvature of the nasalseptum - in 71.6% of patients, hypertrophy of the inferior turbinate - in 59.6%, bulloushypertrophy of the middle turbinate - in 5.5%, hypertrophy of the uncinate process- in 6.4%, hyperpneumatization of Agger nasi cells - in 14.7% of patients. The mostcommon combination was curvature of the nasal septum and hypertrophy of the inferiorturbinates - in 56.0% of cases. Inflammatory pathology in the paranasal sinuses wasin 38.5% of cases: ethmoiditis - in 26.6% of patients, maxillary sinusitis - in 13.8%,sphenoiditis - in 1.8% of patients. In 94.6% of patients, the correction of intranasalpathology was performed simultaneously with EEDCR. In 6.4% of these patients therewere complications - nosebleeding after removal of tampons. Simultaneous operationsdid not significantly increase the percentage and variants of complications comparedwith isolated endonasal operations.Conclusion. The vast majority of patients with chronic dacryocystitis have pathologyof the nasal cavity and paranasal sinuses, which may contribute to the developmentof dacryocystitis and relapse of the disease after operation. Surgical correction ofconcomitant endonasal pathology in patients with chronic dacryocystitis should beperformed simultaneously with endonasal endoscopic dacryocystorhinostomy.
The Image of New Woman as Portrayed in Jhumpa Lahiri’s Novel The Lowland
Authors: Kavitha D. , Neeraja Prof. M. , Neeraja Prof. M.
Published: March 2021

The last decade of the Victorian era witnessed a major shift in the social attitude of the woman. It was a break away from the patriarchal system, and women emerging as independent being and moving towards achieving gender equality. The ‘New Woman’ is considered as a precursor to the feminist movement and thus the legacy of New Woman lives on to this day. Jhumpa Lahiri, the significant writer of the Indian diaspora has emerged on the global literary scene with her remarkable writings. The novel has a compelling plot of family relations. It delineates the tender fraternal bond between Subhash and Udayan and how it gets affected by the various paths they chose in their lives. This intensely emotional tale unfolds diverse dimensions of the woman caught in the predicament of conservative cultural practices at home, political unrest in society and the life of an exile in the immigrant land. It also explores Gauri’s expression of identity, her struggle with love, Bela’s choice for individuality and pragmatism in life has turned the novel into a unique narrative. In her second novel, ‘The Lowland’ Jhumpa portrays her women characters devaluing the patriarchal setup. They break the myths of womanhood and motherhood. Prominence is given to assert their position in society by restoring self-identity than nurturing deeper family relations. They fight with courage and confront various challenges in their marital relationship.
Management concepts of educational institutions in the modern times
Authors: Stankevych Iryna , Tardaskina Tetyana , Sakun Hanna , Bondarenko Olena , Tereshko Yuliia , Ponomarenko Natalia
Published: March 2021

The purpose of the research is to identify the interconnection between the institutional environment, the specifics of educational institutions’ activities and their management model based on national features in the social-cultural characteristics of countries of Eastern and Central Europe. The methodological basis of the research is a combination of theoretical and scientific methods, namely: analysis, synthesis, systematization and comparison, theoretical and logical generalization. Results. Two basic approaches to the management of educational institutions have been identified: the first one is based on the theory of general management, the second one centers around the specifics of educational services. The use of the second approach has been substantiated considering the influence of institutional factors on the management of educational institutions. Based on the analysis of data from different countries, collected in G. Hofstede’s 6-D model, the hypothesis of the existence of differences between the social-cultural features of countries of Central and Eastern European, the former Soviet Union and Western Europe has been tested.
To the assessment of the role of national traits in the processes of the safe operation of nuclear power facilities maintenance
Authors: Karyakin Alexandr , Velikorossov Vladimi , Maksimov Maksim , Prodanova Natalia Alekseevna , Rakauskiene Ona Grazyna , Korechkov Yury , Chernenkaya Liudmila
Published: March 2021

One of the features of the post-Fukushima development of nuclear technologies in terms of the impact of the human factor on safety is the analysis of the national context in the safety culture. The starting point for this thesis is the transboundary nature of the nuclear power safety problem, which, in turn, depends on the ability of people to act together at the national and international levels. Thus, exploring how the national context influences decision-making and the performance of production objectives, and a better understanding of national cultural characteristics, is an important topic to be developed in this article.
The mammoth's mysterious companion: the materials of the Republican ecological and paleontological camp for schoolchildren “Tusk,” years 1997–2013
Authors: Filippova Maiia Petrovna , Maximov Pеtr Dmitrievich , Abramova Vladilena Romanovna , Gogoleva Irina Vasilyevna , Neustroeva Keskileene Ignatovna
Published: March 2021

This article deals with a unique discovery. In 2010, a school expedition found an obscure skull of a woolly rhinoceros on Mamontova Mountain in the Republic of Sakha (Yakutia). Young paleontologists with their leader P. D. Maksimov conducted an anatomical study of the woolly rhinoceros' fossil skull. During the entire period (years 1973–2021) of the camp's existence, young paleontologists have found the remains of 57 animal fossils. All the materials found during the expeditions have been stored in the museum-laboratory at the Republican Ecological-Paleontological Camp of Schoolchildren “Tusk.” Among the gathered paleontological finds, the young researchers were attracted to rhinoceros skulls found at different times near various excavations. The expedition participants have put forward the hypothesis that during the period of the flourishing of the mammoth fauna, there might have been some species or subspecies of woolly rhinoceros on the territory of Paleoyakutia besides the Lena species. The results of the research were highly appreciated by the experts of the republican scientific conferences.
STRATEGI DAN GERAKAN ORGANISASI DAKWAH DALAM PENGEMBANGAN EKONOMI (Studi Kasus Pada Lembaga Keuangan Baitul Maal Wat Tamwi)
Authors: Sabdo Sabdo
Published: March 2021

Bmt merupakan penerapan peraturan ekonomi dari syariat islam. Keberadaan bmt merupakan salah satu media dalam dakwah, yaitu dakwah untuk menyelamatkan manusia dari segala bentuk kemiskinan dan praktik ekonomi dan kapitalis riba yang dipropagandakan oleh kaum kapitalis. Implementasi keberadaan bmt sebagai strategi altrenatif ekonomi dengan berbagai bidangnya : yaitu dalam bentuk penyediaan produk investasi, tabungan dan jasa. Ketiga komponen inilah yang merupakan unsur utama dalam peningkatan ekonomi syariah untuk menyelamatkan manusia dari kemunduran ekonomi.
TAFSIR AL-FATIHAH DALAM TERAPAN
Authors: Rohman Fathur
Published: March 2021

Al-Qur’an adalah mu’jizat yang istimewa. Kitab yang diwahyukan kepada Nabi Muhammad SAW, yang berguna sebagai petunjuk hidup bagi semua manusia untuk menuju jalan yang benar. Al-Fatihah adalah surat yang pertama turun, dan merupakan esensi ataupun induk dari Al-Qur’an itu sendiri. Bahkan siapapun orang Islam yang melaksanakan sholat pasti membaca surat Al-Fatihah. Al-Fatihah berisi tentang beberapa petunjuk: bahwa seorang muslim dalam memulai pekerjaannya haruslah dengan nama Allah SWT, Yang Maha Pemurah dan Maha Penyayang; Yang menguasai di Hari Pembalasan; Kepada-Nya umat Islam beribadah dan meminta pertolongan; dan hanya kepada-Nya umat Islam memohon petunjuk untuk diberikan jalan yang lurus; yaitu jalan orang-orang yang telah diberikan nikmat dan jalan orang-orang yang diridhai oleh Allah swt.
PERSEPSI HIJAB SYAR’I DALAM TREND JILBAB DI KALANGAN REMAJA
Authors: Nurkhomsah Siti
Published: March 2021

Trend hijab syar’i merebak di kalangan remaja, penelitian ini menjelaskan persepsi Remaja Islam masjid Al-I’anah  terhadap persepsi  hijab syar’i dan trend hijab. Penelitian ini bersifat deskriptif -kualitatif Penelitian ini menggambarkan bahwa persepsi Remaja Masjid Al-I’anah terhadap Hijab Syar’i bahwa hijab Syar’i merupakan suatu trend masa kini, Dan Pemahaman terhadap jilbab merupakan kerudung (khimar) bukan sejenis baju kurung atau gamis. Remaja Masjid Al-I’anah menyadari bahwa kewajiban sebagai seorang muslimah adalah mengenakan jilbab yang sesuai syariat Islam  dan merasakan manfaat mengenakan jilbab baik secara rohani maupun jasmani.