bluuebunny/crossref_metadata_2025 huggingface dataset:
Network-Based Differential Analysis to Identify Molecular Features of Tumorigenesis for Esophageal Squamous Carcinoma
Authors: Jiang Suxia , Zhang Qi , Su Yansen , Pan Linqiang
Published: January 2018

Esophageal cancer has a poor prognosis and high mortality rate across the world. The diagnosis and treatment of esophageal cancer are hindered by the limited knowledge about the pathogenesis mechanisms of esophageal cancer. Esophageal cancer has two major subtypes, squamous and adenocarcinoma. In this work, we proposed a method to select candidate biomarkers of esophageal squamous carcinoma based on the topological differential analysis between the gene–gene interaction networks for esophageal squamous carcinoma and normal cells. We established the gene–gene interaction networks for esophageal squamous carcinoma and normal based on the correlation of genes. For each gene, we firstly calculated and compared five centrality measures, which could reflect the topological property of a network. According to five centrality measures, the genes with large differences between the two networks were regarded as candidate biomarkers for esophageal squamous carcinoma. A total of 21 candidate biomarkers were identified for esophageal squamous carcinoma, and seven of them have been confirmed to be biomarkers of esophageal-12 squamous carcinoma by previous research. In addition, six genes (RBPMS2, PDK4, IGK, SBSN, IFIT3 and HSPB6) were likely to be the biomarkers of tumorigenesis for esophageal squamous carcinoma due to the fact that the biological processes in which they participate are closely related with the development of esophageal squamous carcinoma. Statistical analysis indicates that effectiveness of the detected biomarkers of esophageal squamous carcinoma. The proposed method could be extended to other complex diseases for detecting the molecular features of pathopoiesis and targets for targeted therapy.
Beneficial Effects of Monascus sp. KCCM 10093 Pigments and Derivatives: A Mini Review
Authors: Kim Daehwan , Ku Seockmo
Published: January 2018

The production of Monascus pigments and related byproducts, via microbial fermentation, has been broadly utilized as coloring by traditional food industries and as a natural textile dye. In addition to these traditional purposes, Monascus pigments have been recently favored for a variety of commercial and academic purposes. Pigments and derivatives formed during Monascus fermentation have pharmaceutical and clinical properties that can counteract common diseases, including obesity, type-2 diabetes, and cancer. Various research attempts have investigated the optimum conditions for this derived compound synthesis, as well as the still-unknown bio-functional effects. Recently, several studies were conducted using Monascus sp. KCCM 10093 and its derivatives. These experimental outcomes potentially reflect the bio-functional features of Monascus sp. KCCM 10093. However, no publication to date provides an overview of Monascus sp. KCCM 10093’s unique metabolite products, functionalities, or biological pathways. In order to develop profitable commercial applications of Monascus sp. KCCM 10093, it is necessary not only to conduct continuous research, but also to systematically organize previous Monascus studies. The goals of this review are to investigate the current derivatives of Monascus sp. KCCM 10093 pigments—some of which have demonstrated newly-identified functionality—and the relevant uses of these molecules for pharmaceutical or nutraceutical purposes.
SistematX, an Online Web-Based Cheminformatics Tool for Data Management of Secondary Metabolites
Authors: Scotti Marcus , Herrera-Acevedo Chonny , Oliveira Tiago , Costa Renan , Santos Silas , Rodrigues Ricardo , Scotti Luciana , Da-Costa Fernando
Published: January 2018

The traditional work of a natural products researcher consists in large part of time-consuming experimental work, collecting biota to prepare and analyze extracts and to identify innovative metabolites. However, along this long scientific path, much information is lost or restricted to a specific niche. The large amounts of data already produced and the science of metabolomics reveal new questions: Are these compounds known or new? How fast can this information be obtained? To answer these and other relevant questions, an appropriate procedure to correctly store information on the data retrieved from the discovered metabolites is necessary. The SistematX (http://sistematx.ufpb.br) interface is implemented considering the following aspects: (a) the ability to search by structure, SMILES (Simplified Molecular-Input Line-Entry System) code, compound name and species; (b) the ability to save chemical structures found by searching; (c) compound data results include important characteristics for natural products chemistry; and (d) the user can find specific information for taxonomic rank (from family to species) of the plant from which the compound was isolated, the searched-for molecule, and the bibliographic reference and Global Positioning System (GPS) coordinates. The SistematX homepage allows the user to log into the data management area using a login name and password and gain access to administration pages. In this article, we introduced a modern and innovative web interface for the management of a secondary metabolite database. With its multiplatform design, it is able to be properly consulted via the internet and managed from any accredited computer. The interface provided by SistematX contains a wealth of useful information for the scientific community about natural products, highlighting the locations of species from which compounds are isolated.
Improvement in Electrode Performance of Novel SWCNT Loaded Three-Dimensional Porous RVC Composite Electrodes by Electrochemical Deposition Method
Authors: Aldalbahi Ali , Rahaman Mostafizur , Almoigli Mohammed , Meriey Al , Alharbi Khalid
Published: January 2018

The three-dimensional (3D) composite electrodes were prepared by depositing different amounts of acid-functionalized single-walled carbon nanotubes (a-SWCNTs) on porous reticulated vitreous carbon (RVC) through the electrochemical deposition method. The SWCNT was functionalized by the reflux method in nitric acid and was proven by Raman and visible spectra. The optimum time for sonication to disperse the functionalized SWCNT (a-SWCNT) in dimethyl formamide (DMF) well was determined by UV spectra. The average pore size of RVC electrodes was calculated from scanning electron microscopy (SEM) images. Moreover, the surface morphology of composite electrodes was also examined by SEM study. All 3D electrodes were evaluated for their electrochemical properties by cyclic voltammetry. The result showed that the value of specific capacitance of the electrode increases with the increase in the amount of a-SWCNT in geometric volume. However, the value of specific capacitance per gram decreases with the increase in scan rate as well as the amount of a-SWCNT. The stability of the electrodes was also tested. This revealed that all the electrodes were stable; however, lower a-SWCNT-loaded electrodes had excellent cyclic stability. These results suggest that the a-SWCNT-coated RVC electrodes have promise as an effective technology for desalination.
Concentrations of Plasma Free Palmitoleic and Dihomo-Gamma Linoleic Fatty Acids Are Higher in Children with Abdominal Obesity
Authors: Aristizabal Juan , González-Zapata Laura , Estrada-Restrepo Alejandro , Monsalve-Alvarez Julia , Restrepo-Mesa Sandra , Gaitán Diego
Published: January 2018

Increased plasma free fatty acids (FFAs) are associated with cardiometabolic risk factors in adults with abdominal obesity (AO). However, this association remains controversial in children. This study analyzed plasma FFA concentration in children with and without AO. Twenty-nine children classified with AO were matched by age and sex with 29 non-obese individuals. Blood samples were collected after fasting for 10–12 h. Plasma concentration of glucose, insulin, triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were determined by automatized methods. FFAs were analyzed by gas chromatography. Children with and without AO had similar age (7.1 ± 2.6 vs. 7.2 ± 2.7 years; p > 0.05) but obese children showed higher (p < 0.05) body mass index (BMI) (+4.3 kg/m2), systolic blood pressure (+5.1 mmHg), and insulin (+27.8 pmol/L). There were no significant differences in plasma total FFA concentration between groups (1.02 ± 0.61 vs. 0.89 ± 0.37 mmol/L; p > 0.05). However, children with AO had higher palmitoleic acid (0.94 vs. 0.70 wt %; p < 0.05) and dihomo-gamma linoleic acid (DHGL) (2.76 vs. 2.07 wt %; p < 0.05). Palmitoleic and DHGL acids correlated (p < 0.05) with BMI (r = 0.397; r = 0.296, respectively) and with waist circumference (r = 0.380; r = 0.276, respectively). Palmitoleic acid correlated positively with systolic blood pressure (r = 0.386; p < 0.05) and negatively with HDL-C (−0.572; p < 0.01). In summary, children with AO have higher plasmatic concentrations of free palmitoleic and DHGL fatty acids, which correlate with cardiometabolic risk factors.
Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas
Authors: El-Demerdash Amr , Atanasov Atanas , Bishayee Anupam , Abdel-Mogib Mamdouh , Hooper John , Al-Mourabit Ali
Published: January 2018

Pyrroloquinoline and guanidine-derived alkaloids present distinct groups of marine secondary metabolites with structural diversity that displayed potentialities in biological research. A considerable number of these molecular architectures had been recorded from marine sponges belonging to different marine genera, including Batzella, Crambe, Monanchora, Clathria, Ptilocaulis and New Caledonian starfishes Fromia monilis and Celerina heffernani. In this review, we aim to comprehensively cover the chemodiversity and the bioactivities landmarks centered around the chemical constituents exclusively isolated from these three marine genera including Batzella, Crambe and Monanchora over the period 1981–2017, paying a special attention to the polycyclic guanidinic compounds and their proposed biomimetic landmarks. It is concluded that these marine sponge genera represent a rich source of novel compounds with potential applications for cancer and other therapeutic areas.
Metabolic Responses to Carbohydrate Ingestion during Exercise: Associations between Carbohydrate Dose and Endurance Performance
Authors: Newell Michael , Wallis Gareth , Hunter Angus , Tipton Kevin , Galloway Stuart
Published: January 2018

Carbohydrate (CHO) ingestion during exercise lasting less than three hours improves endurance exercise performance but there is still debate about the optimal dose. We utilised stable isotopes and blood metabolite profiles to further examine metabolic responses to CHO (glucose only) ingestion in the 20–64 g·h−1 range, and to determine the association with performance outcome. In a double-blind, randomized cross-over design, male cyclists (n = 20, mean ± SD, age 34 ± 10 years, mass 75.8 ± 9 kg, peak power output 394 ± 36 W, VO2max 62 ± 9 mL·kg−1·min−1) completed four main experimental trials. Each trial involved a two-hour constant load ride (185 ± 25 W) followed by a time trial, where one of three CHO beverages, or a control (water), were administered every 15 min, providing 0, 20, 39 or 64 g CHO·h−1. Dual glucose tracer techniques, indirect calorimetry and blood analyses were used to determine glucose kinetics, exogenous CHO oxidation (EXO), endogenous CHO and fat oxidation; and metabolite responses. Regression analysis revealed that total exogenous CHO oxidised in the second hour of exercise, and suppression of serum NEFA concentration provided the best prediction model of performance outcome. However, the model could only explain ~19% of the variance in performance outcome. The present data demonstrate that consuming ~40 g·h−1 of CHO appears to be the minimum ingestion rate required to induce metabolic effects that are sufficient to impact upon performance outcome. These data highlight a lack of performance benefit and few changes in metabolic outcomes beyond an ingestion rate of 39 g·h−1. Further work is required to explore dose-response effects of CHO feeding and associations between multiple metabolic parameters and subsequent performance outcome.
Impact of Pharmacist-Conducted Comprehensive Medication Reviews for Older Adult Patients to Reduce Medication Related Problems
Authors: Kiel Whitney , Phillips Shaun
Published: January 2018

Older adults are demanding increased healthcare attention with regards to prescription use due in large part to highly complex medication regimens. As patients age, medications often have a more pronounced effect on older adults, negatively impacting patient safety and increasing healthcare costs. Comprehensive medication reviews (CMRs) optimize medications for elderly patients and help to avoid inappropriate medication use. Previous literature has shown that such CMRs can successfully identify and reduce the number of medication-related problems and improve acute healthcare utilization. The purpose of this pharmacy resident research study is to examine the impact of pharmacist-conducted geriatric medication reviews to reduce medication-related problems within a leading community health system in southwest Michigan. Furthermore, the study examines type of pharmacist interventions made during medication reviews, acute healthcare utilization, and physician assessment of the pharmacist’s value. The study was conducted as a retrospective post-hoc analysis on ambulatory patients who received a CMR by a pharmacist at a primary care practice. Inclusion criteria included patients over 65 years of age with concurrent use of at least five medications who were a recent recipient of a CMR. Exclusion criteria included patients with renal failure, or those with multiple providers involved in primary care. The primary outcome was the difference in number of medication-related problems, as defined by the START and STOPP Criteria (Screening Tool to Alert doctors to Right Treatment/Screening Tool of Older Persons’ Prescriptions). Secondary outcomes included hospitalizations, emergency department visits, number and type of pharmacist interventions, acceptance rate of pharmacist recommendations, and assessment of the pharmacist’s value by clinic providers. There were a total of 26 patients that received a comprehensive medication review from the pharmacist and were compared to a control group, patients that did not receive a CMR. The average patient age for both groups was 76 years old. A total of 11 medication-related problems in the intervention group patients were identified compared with 24 medication-related problems in the control group (p-value 0.002). Pharmacist-led comprehensive medication reviews were associated with a statistically significant different in the number of medication-related problems as defined by the START and STOPP criteria.
Improved Processability and the Processing-Structure-Properties Relationship of Ultra-High Molecular Weight Polyethylene via Supercritical Nitrogen and Carbon Dioxide in Injection Molding
Authors: Yilmaz Galip , Ellingham Thomas , Turng Lih-Sheng
Published: January 2018

The processability of injection molding ultra-high molecular weight polyethylene (UHMWPE) was improved by introducing supercritical nitrogen (scN2) or supercritical carbon dioxide (scCO2) into the polymer melt, which decreased its viscosity and injection pressure while reducing the risk of degradation. When using the special full-shot option of microcellular injection molding (MIM), it was found that the required injection pressure decreased by up to 30% and 35% when scCO2 and scN2 were used, respectively. The mechanical properties in terms of tensile strength, Young’s modulus, and elongation-at-break of the supercritical fluid (SCF)-loaded samples were examined. The thermal and rheological properties of regular and SCF-loaded samples were analyzed using differential scanning calorimetry (DSC) and parallel-plate rheometry, respectively. The results showed that the temperature dependence of UHMWPE was very low, suggesting that increasing the processing temperature is not a viable method for reducing injection pressure or improving processability. Moreover, the use of scN2 and scCO2 with UHMWPE and MIM retained the high molecular weight, and thus the mechanical properties, of the polymer, while regular injection molding led to signs of degradation.
Vascular Cell Co-Culture on Silk Fibroin Matrix
Authors: Tu Fangfang , Liu Yunfei , Li Helei , Shi Pange , Hao Yunxia , Wu Yue , Yi Honggen , Yin Yin , Wang Jiannan
Published: January 2018

Silk fibroin (SF), a natural polymer material possessing excellent biocompatibility and biodegradability, and has been widely used in biomedical applications. In order to explore the behavior of vascular cells by co-culturing on regenerated SF matrix for use as artificial blood vessels, human aorta vascular smooth muscle cells (HAVSMCs) were co-cultured with human arterial fibroblasts (HAFs) or human umbilical vein endothelial cells (HUVECs) on SF films and SF tubular scaffolds (SFTSs). Analysis of cell morphology and deoxyribonucleic acid (DNA) content showed that HUVECs, HAVSMCs and HAFs adhered and spread well, and exhibited high proliferative activity whether cultured alone or in co-culture. Immunofluorescence and scanning electron microscopy (SEM) analysis showed that HUVECs and HAFs co-existed well with HAVSMCs on SF films or SFTSs. Cytokine expression determined by reverse transcription-polymerase chain reaction (RT-PCR) indicated that the expression levels of α-smooth muscle actin (α-SMA) and smooth muscle myosin heavy chain (SM-MHC) in HAVSMCs were inhibited on SF films or SFTSs, but expression could be obviously promoted by co-culture with HUVECs or HAFs, especially that of SM-MHC. On SF films, the expression of vascular endothelial growth factor (VEGF) and platelet endothelial cell adhesion molecule-1 (CD31) in HUVECs was promoted, and the expression levels of both increased obviously when co-cultured with HAVSMCs, with the expression levels of VEGF increasing with increasing incubation time. The expression levels of VEGF and CD31 in cells co-cultured on SFTSs improved significantly from day 3 compared with the mono-culture group. These results were beneficial to the mechanism analysis on vascular cell colonization and vascular tissue repair after in vivo transplantation of SFTSs.
Advancing Scientific Knowledge: Ethical Issues in the Journal Publication Process
Authors: McCuen Richard
Published: January 2018

The goal of this paper is to assess the journal publication process from value and ethical perspectives. The specific objectives are: (1) To define fundamental values relevant to scientific journal publication; (2) To identify stakeholders involved in professional journals and their value rights and responsibilities; (3) To discuss the steps of the journal publication process where ethical dilemmas arise and the potential influences of such dilemmas on the advancement of knowledge; and (4) To summarize actions that can minimize unethical practices throughout the steps of the publication process. Values such as honesty, efficiency, accountability, and fairness will be discussed. Issues related to the various stakeholders such as self-citation, plagiarism, dual publication, a lack of timeliness, and issues related to authorship will be a primary focus.
Description, Prescription, and Value in the Study of Religion
Authors: Ranganathan Bharat
Published: January 2018

The study of religion is commonly divided into two sides. On the one side is the descriptive approach, including social scientific and historical scholars who seek to account for religion as it has been practiced. On the other side is the prescriptive approach, including religious ethicists, philosophers of religion, and theologians who seek to evaluate and prescribe religious practices and beliefs. But is this divide desirable or even tenable? Some scholars believe so, holding that the proper aim of religious studies ought to be delimited to the analysis and description of religious phenomena. Such a view, however, excludes those who pursue prescriptive inquiry. The contributors to this focus issue are trained primarily in either descriptive or prescriptive methodologies. Through their respective contributions, they highlight how they understand and may offer ways past the seemingly ossified division within religious studies, focusing especially on the nature and place of value in the study of religion.
The Distance between Zurich and Todtnauberg
Authors: Anderson A.
Published: January 2018

This paper focuses on two poems written by Paul Celan after first encounters he had with writers who held great significance for him. In 1960 Celan met fellow Jewish poet Nelly Sachs at the Stork Inn in Zurich, and afterwards recorded the event in the poem “Zürich, Zum Storchen”. Seven years later, Celan visited Martin Heidegger at his hut in the German mountains. Celan’s depiction of this encounter is found in the poem “Todtnauberg”. In this essay, I make a two-fold argument regarding the Zurich poem. First I claim that “Todtnauberg” is clearly crafted in light of the earlier Sachs text, a fact that has been overlooked by previous scholarship. As such, it is only in placing the two texts side by side that a complete understanding of “Todtnauberg” comes into view. Second I will indicate how the Zurich poem reflects key elements of an approach to the problem of evil that I term an “enestological theodicy.” Such a term needed to be coined, since this sort of theodicy does not fit in the more traditional narrative categories related to the problem of evil.
Technology Acceptance and User-Centred Design of Assistive Exoskeletons for Older Adults: A Commentary
Authors: Shore Linda , Power Valerie , De Eyto Adam , O’Sullivan Leonard
Published: January 2018

Assistive robots are emerging as technologies that enable older adults to perform activities of daily living with autonomy. Exoskeletons are a subset of assistive robots that can support mobility. Perceptions and acceptance of these technologies require understanding in a user-centred design context to ensure optimum experience and adoption by as broad a spectrum of older adults as possible. The adoption and use of assistive robots for activities of daily living (ADL) by older adults is poorly understood. Older adult acceptance of technology is affected by numerous factors, such as perceptions and stigma associated with dependency and ageing. Assistive technology (AT) models provide theoretical frameworks that inform decision-making in relation to assistive devices for people with disabilities. However, technology acceptance models (TAMs) are theoretical explanations of factors that influence why users adopt some technologies and not others. Recent models have emerged specifically describing technology acceptance by older adults. In the context of exoskeleton design, these models could influence design approaches. This article will discuss a selection of TAMs, displaying a chronology that highlights their evolution, and two prioritised TAMs—Almere and the senior technology acceptance model (STAM)—that merit consideration when attempting to understand acceptance and use of assistive robots by older adults.
Using Multitemporal Sentinel-1 C-band Backscatter to Monitor Phenology and Classify Deciduous and Coniferous Forests in Northern Switzerland
Authors: Rüetschi Marius , Schaepman Michael , Small David
Published: January 2018

Efficient methods to monitor forested areas help us to better understand their processes. To date, only a few studies have assessed the usability of multitemporal synthetic aperture radar (SAR) datasets in this context. Here we present an analysis of an unprecedented set of C-band observations of mixed temperate forests. We demonstrate the potential of using multitemporal C-band VV and VH polarisation data for monitoring phenology and classifying forests in northern Switzerland. Each SAR acquisition was first radiometrically terrain corrected using digital elevation model-based image simulations of the local illuminated area. The flattened backscatter values and the local area values were input to a temporal compositing process integrating backscatter values from ascending and descending tracks. The process used local resolution weighting of each input, producing composite backscatter values that strongly mitigated terrain-induced distortions. Several descriptors were calculated to show the seasonal variation of European beech (Fagus sylvatica), oak (Quercus robur, Quercus petraea) and Norway spruce (Picea abies) in C-band data. Using their distinct seasonal signatures, the timing of leaf emergence and leaf fall of the deciduous species were estimated and compared to available ground observations. Furthermore, classifications for the forest types ‘deciduous’ and ‘coniferous’ and the investigated species were implemented using random forest classifiers. The deciduous species backscatter was about 1 dB higher than spruce throughout the year in both polarisations. The forest types showed opposing seasonal backscatter behaviours. At VH, deciduous species showed higher backscatter in winter than in summer, whereas spruce showed higher backscatter in summer than in winter. In VV, this pattern was similar for spruce, while no distinct seasonal behaviour was apparent for the deciduous species. The time differences between the estimations and the ground observations of the phenological events were approximately within the error margin ( ± 12 days) of the temporal resolution. The classification performances were promising, with higher accuracies achieved for the forest types (OA of 86% and κ = 0.73) than for individual species (OA of 72% and κ = 0.58). These results show that multitemporal C-band backscatter data have significant potential to supplement optical remote sensing data for ecological studies and mapping of mixed temperate forests.
Sensitivity of BRDF, NDVI and Wind Speed to the Aerodynamic Roughness Length over Sparse Tamarix in the Downstream Heihe River Basin
Authors: Xing Qiang , Wu Bingfang , Yan Nana , Yu Mingzhao , Zhu Weiwei
Published: January 2018

The aerodynamic roughness length (z0m) is an important parameter that affects the momentum and energy exchange between the earth surface’s and the atmosphere. In this paper, the gradient wind speed data that were observed from May to October, 2014, at the Si Daoqiao station, which is located in an area of sparse Tamarix in the downstream region of the Heihe River Basin (HRB), are used to evaluate the sensitivity of the moderate-resolution imaging spectroradiometer (MODIS) near-infrared (NIR) bi-directional reflectance distribution function (BRDF) R, the MODIS/Landsat 8 normalized difference vegetation index (NDVI), and the wind speed at 5 m in comparison with the field-measured z0m. The results indicate that the NIR BRDF_R_MODIS and the NDVIMODIS/NDVILandsat8 are less sensitive indicators of the z0m over sparse Tamarix areas (R2: 0.0045 for NIR BRDF_RMODIS; R2: 0.0342 for NDVIMODIS; and, R2: 0.1646 for NDVILandsat8), which differs significantly from the results obtained by previous studies for farmlands and grasslands. However, there is a nearly linear correlation between the wind speed at 5 m and the z0m at the time scale of the NDVILandsat8 acquisitions (R2: 0.3696). Furthermore, the combination of the NDVI and wind speed at 5 m can significantly improve this correlation (R2: 0.7682 for NDVIMODIS; R2: 0.6304 for NDVILandsat8), whereas the combination of the NIR BRDF_RMODIS and wind speed at 5 m still has a low correlation (R2: 0.0886). Finally, the regional z0m of the oasis in the downstream region of the HRB was determined using Landsat 8 surface reflectance data and the wind speed data at the Si Daoqiao station, which properly reflect the temporal evolution of the z0m in that region. The parameterization scheme proposed in this paper has great potential to be applied to evapotranspiration, land surface, and hydrologic model simulations of sparse Tamarix at Si Daoqiao site in the future.
Performance Comparison with Different Antenna Properties in Time Reversal Ultra-Wideband Communications for Sensor System Applications
Authors: Yang Yu , Wang Bing-Zhong , Ding Shuai
Published: January 2018

The complexity reduction of receivers in ultrawideband (UWB) communication when time reversal (TR) technique is applied makes it suitable for low-cost and low-power sensor systems. Larger antenna dispersion can generally lead to a less stable phase center and will increase the interference in UWB communications based on pulse radio, whereas a higher antenna gain will result in higher channel gain and further larger channel capacity. To find out the trade-off between antenna gain and dispersion, we performed the channel measurements using different antennas in a dense multipath environment and established the distribution of channel capacities based on the measured channel responses. The results show that the capacity loss caused by antenna dispersion cannot be compensated by antenna gain with line-of-sight transmission to some extent, the effect of phase center on the communication system is negligible, and antennas with smaller time dispersion will have a better energy focusing property and anti-interference performance in TR systems.
A Review of Oil Spill Remote Sensing
Authors: Fingas Merv , Brown Carl
Published: January 2018

The technical aspects of oil spill remote sensing are examined and the practical uses and drawbacks of each technology are given with a focus on unfolding technology. The use of visible techniques is ubiquitous, but limited to certain observational conditions and simple applications. Infrared cameras offer some potential as oil spill sensors but have several limitations. Both techniques, although limited in capability, are widely used because of their increasing economy. The laser fluorosensor uniquely detects oil on substrates that include shoreline, water, soil, plants, ice, and snow. New commercial units have come out in the last few years. Radar detects calm areas on water and thus oil on water, because oil will reduce capillary waves on a water surface given moderate winds. Radar provides a unique option for wide area surveillance, all day or night and rainy/cloudy weather. Satellite-carried radars with their frequent overpass and high spatial resolution make these day–night and all-weather sensors essential for delineating both large spills and monitoring ship and platform oil discharges. Most strategic oil spill mapping is now being carried out using radar. Slick thickness measurements have been sought for many years. The operative technique at this time is the passive microwave. New techniques for calibration and verification have made these instruments more reliable.
Low-Cost Servomotor Driver for PFM Control
Authors: Aragon-Jurado David , Morgado-Estevez Arturo , Perez-Peña Fernando
Published: January 2018

Servomotors have already been around for some decades and they are extremely popular among roboticists due to their simple control technique, reliability and low-cost. They are usually controlled by using Pulse Width Modulation (PWM) and this paper aims to keep the idea of simplicity and low-cost, while introducing a new control technique: Pulse Frequency Modulation (PFM). The objective of this paper is to focus on our development of a low-cost servomotor controller which will allow the research community to use them with PFM. A low-cost commercial servomotor is used as the base system for the development: a small PCB that fits inside the case and allocates all the electronic components to control the motor has been designed to replace the original. The potentiometer is retained as the feedback sensor and a microcontroller is responsible for controlling the position of the motor. The paper compares the performance of a PWM and a PFM controlled servomotor. The comparison shows that the servomotor with our controller achieves a faster mechanism for switching targets and a lower latency. This controller can be used with neuromorphic systems to remove the conversion from events to PWM.
Identification of Coffee Varieties Using Laser-Induced Breakdown Spectroscopy and Chemometrics
Authors: Zhang Chu , Shen Tingting , Liu Fei , He Yong
Published: January 2018

We linked coffee quality to its different varieties. This is of interest because the identification of coffee varieties should help coffee trading and consumption. Laser-induced breakdown spectroscopy (LIBS) combined with chemometric methods was used to identify coffee varieties. Wavelet transform (WT) was used to reduce LIBS spectra noise. Partial least squares-discriminant analysis (PLS-DA), radial basis function neural network (RBFNN), and support vector machine (SVM) were used to build classification models. Loadings of principal component analysis (PCA) were used to select the spectral variables contributing most to the identification of coffee varieties. Twenty wavelength variables corresponding to C I, Mg I, Mg II, Al II, CN, H, Ca II, Fe I, K I, Na I, N I, and O I were selected. PLS-DA, RBFNN, and SVM models on selected wavelength variables showed acceptable results. SVM and RBFNN models performed better with a classification accuracy of over 80% in the prediction set, for both full spectra and the selected variables. The overall results indicated that it was feasible to use LIBS and chemometric methods to identify coffee varieties. For further studies, more samples are needed to produce robust classification models, research should be conducted on which methods to use to select spectral peaks that correspond to the elements contributing most to identification, and the methods for acquiring stable spectra should also be studied.
A Novel Approach to Monitoring the Curing of Epoxy in Closed Tools by Use of Ultrasonic Spectroscopy
Authors: Pommer Christian , Sinapius Michael
Published: January 2018

The increasing use of composite materials has led to a greater demand for efficient curing cycles to reduce costs and speed up production cycles in manufacturing. One method to achieve this goal is in-line cure monitoring to determine the exact curing time. This article proposes a novel method through which to monitor the curing process inside closed tools by employing ultrasonic spectroscopy. A simple experiment is used to demonstrate the change in the ultrasonic spectrum during the cure cycle of an epoxy. The results clearly reveal a direct correlation between the amplitude and state of cure. The glass transition point is indicated by a global minimum of the reflected amplitude.
A Localized Surface Plasmon Resonance Sensor Using Double-Metal-Complex Nanostructures and a Review of Recent Approaches
Authors: Ahn Heesang , Song Hyerin , Choi Jong-ryul , Kim Kyujung
Published: January 2018

From active developments and applications of various devices to acquire outside and inside information and to operate based on feedback from that information, the sensor market is growing rapidly. In accordance to this trend, the surface plasmon resonance (SPR) sensor, an optical sensor, has been actively developed for high-sensitivity real-time detection. In this study, the fundamentals of SPR sensors and recent approaches for enhancing sensing performance are reported. In the section on the fundamentals of SPR sensors, a brief description of surface plasmon phenomena, SPR, SPR-based sensing applications, and several configuration types of SPR sensors are introduced. In addition, advanced nanotechnology- and nanofabrication-based techniques for improving the sensing performance of SPR sensors are proposed: (1) localized SPR (LSPR) using nanostructures or nanoparticles; (2) long-range SPR (LRSPR); and (3) double-metal-layer SPR sensors for additional performance improvements. Consequently, a high-sensitivity, high-biocompatibility SPR sensor method is suggested. Moreover, we briefly describe issues (miniaturization and communication technology integration) for future SPR sensors.
A Fully Integrated Paper-Microfluidic Electrochemical Device for Simultaneous Analysis of Physiologic Blood Ions
Authors: Jin Joon-Hyung , Kim Joon , Lee Sang , Choi Sam , Park Chan , Min Nam
Published: January 2018

A fully integrated paper microfluidic electrochemical device equipped with three different cation permeable films is developed to determine blood ions (Cl−, Na+, K+, and Ca2+) at a time. These blood ions that are normally dissolved in the real human blood stream are essential for cell metabolisms and homeostasis in the human body. Abnormal concentration of blood ions causes many serious disorders. The optimized microfluidic device working without any external power source can directly and effectively separate human blood components, and subsequently detect a specific blood ion with minimized interference. The measured sensitivity to Cl−, K+, Na+, and Ca2+ are −47.71, 45.97, 51.06, and 19.46 in mV decade−1, respectively. Potentiometric responses of the microfluidic devices to blood serum samples are in the normal ranges of each cation, and comparable with responses from the commercial blood ion analyzer Abbott i-Stat.
In-Orbit Performance Evaluation of a Spaceborne High Precision Fiber Optic Gyroscope
Authors: Jin Jing , Zhang Ting , Kong Linghai , Ma Kun
Published: January 2018

An in-orbit experiment was launched to evaluate the performance of the spaceborne high precision fiber optic gyroscopes (FOG). The three-axis in-orbit data of the FOG were analyzed using wavelet analysis method. Features of low frequency period terms and glitch noise were demonstrated. In addition, a method to extract the random noise from the in-orbit data is proposed based on the first-order difference method and the Pauta criterion. In addition, the random walk coefficient (RWC) of the FOG was calculated with the Allan variance method. Compared the ground test results, the in-orbit performance evaluation of Spaceborne High Precision Fiber Optic Gyroscope was verified.
Highly Integrated MEMS-ASIC Sensing System for Intracorporeal Physiological Condition Monitoring
Authors: Xue Ning , Wang Chao , Liu Cunxiu , Sun Jianhai
Published: January 2018

In this paper, a highly monolithic-integrated multi-modality sensor is proposed for intracorporeal monitoring. The single-chip sensor consists of a solid-state based temperature sensor, a capacitive based pressure sensor, and an electrochemical oxygen sensor with their respective interface application-specific integrated circuits (ASICs). The solid-state-based temperature sensor and the interface ASICs were first designed and fabricated based on a 0.18-μm 1.8-V CMOS (complementary metal-oxide-semiconductor) process. The oxygen sensor and pressure sensor were fabricated by the standard CMOS process and subsequent CMOS-compatible MEMS (micro-electromechanical systems) post-processing. The multi-sensor single chip was completely sealed by the nafion, parylene, and PDMS (polydimethylsiloxane) layers for biocompatibility study. The size of the compact sensor chip is only 3.65 mm × 1.65 mm × 0.72 mm. The functionality, stability, and sensitivity of the multi-functional sensor was tested ex vivo. Cytotoxicity assessment was performed to verify that the bio-compatibility of the device is conforming to the ISO 10993-5:2009 standards. The measured sensitivities of the sensors for the temperature, pressure, and oxygen concentration are 10.2 mV/°C, 5.58 mV/kPa, and 20 mV·L/mg, respectively. The measurement results show that the proposed multi-sensor single chip is suitable to sense the temperature, pressure, and oxygen concentration of human tissues for intracorporeal physiological condition monitoring.
Application of Near Infrared Reflectance Spectroscopy for Rapid and Non-Destructive Discrimination of Hulled Barley, Naked Barley, and Wheat Contaminated with Fusarium
Authors: Lim Jongguk , Kim Giyoung , Mo Changyeun , Oh Kyoungmin , Kim Geonseob , Ham Hyeonheui , Kim Seongmin , Kim Moon
Published: January 2018

Fusarium is a common fungal disease in grains that reduces the yield of barley and wheat. In this study, a near infrared reflectance spectroscopic technique was used with a statistical prediction model to rapidly and non-destructively discriminate grain samples contaminated with Fusarium. Reflectance spectra were acquired from hulled barley, naked barley, and wheat samples contaminated with Fusarium using near infrared reflectance (NIR) spectroscopy with a wavelength range of 1175–2170 nm. After measurement, the samples were cultured in a medium to discriminate contaminated samples. A partial least square discrimination analysis (PLS-DA) prediction model was developed using the acquired reflectance spectra and the culture results. The correct classification rate (CCR) of Fusarium for the hulled barley, naked barley, and wheat samples developed using raw spectra was 98% or higher. The accuracy of discrimination prediction improved when second and third-order derivative pretreatments were applied. The grains contaminated with Fusarium could be rapidly discriminated using spectroscopy technology and a PLS-DA discrimination model, and the potential of the non-destructive discrimination method could be verified.
Atmospheric Sensors and Energy Harvesters on Overhead Power Lines
Authors: White Richard , Nguyen Duy-Son , Wu Zhiwei , Wright Paul
Published: January 2018

We demonstrate the feasibility of using novel, small energy harvesters to power atmospheric sensors and radios simply attached to a single conductor of existing overhead power distribution lines. We demonstrate the ability to harvest the required power for operating multiple atmospheric and power-system sensors, together with short-range radios that could broadcast atmospheric sensor data to the cellphones of people nearby. Occasional long-range broadcasts of the data could also be made of both atmospheric and power-line conditions.
HARE: Supporting Efficient Uplink Multi-Hop Communications in Self-Organizing LPWANs
Authors: Adame Vázquez Toni , Barrachina-Muñoz Sergio , Bellalta Boris , Bel Albert
Published: January 2018

The emergence of low-power wide area networks (LPWANs) as a new agent in the Internet of Things (IoT) will result in the incorporation into the digital world of low-automated processes from a wide variety of sectors. The single-hop conception of typical LPWAN deployments, though simple and robust, overlooks the self-organization capabilities of network devices, suffers from lack of scalability in crowded scenarios, and pays little attention to energy consumption. Aimed to take the most out of devices’ capabilities, the HARE protocol stack is proposed in this paper as a new LPWAN technology flexible enough to adopt uplink multi-hop communications when proving energetically more efficient. In this way, results from a real testbed show energy savings of up to 15% when using a multi-hop approach while keeping the same network reliability. System’s self-organizing capability and resilience have been also validated after performing numerous iterations of the association mechanism and deliberately switching off network devices.
Design and Performance of a Pinned Photodiode CMOS Image Sensor Using Reverse Substrate Bias
Authors: Stefanov Konstantin , Clarke Andrew , Ivory James , Holland Andrew
Published: January 2018

A new pinned photodiode (PPD) CMOS image sensor with reverse biased p-type substrate has been developed and characterized. The sensor uses traditional PPDs with one additional deep implantation step to suppress the parasitic reverse currents, and can be fully depleted. The first prototypes have been manufactured on an 18 µm thick, 1000 Ω·cm epitaxial silicon wafers using 180 nm PPD image sensor process. Both front-side illuminated (FSI) and back-side illuminated (BSI) devices were manufactured in collaboration with Teledyne e2v. The characterization results from a number of arrays of 10 µm and 5.4 µm PPD pixels, with different shape, the size and the depth of the new implant are in good agreement with device simulations. The new pixels could be reverse-biased without parasitic leakage currents well beyond full depletion, and demonstrate nearly identical optical response to the reference non-modified pixels. The observed excessive charge sharing in some pixel variants is shown to not be a limiting factor in operation. This development promises to realize monolithic PPD CIS with large depleted thickness and correspondingly high quantum efficiency at near-infrared and soft X-ray wavelengths.
Applying ExpandNet’s Systematic Approach to Scaling Up in an Integrated Population, Health and Environment Project in East Africa
Authors: Omimo Antony , Taranta Dorah , Ghiron Laura , Kabiswa Charles , Aibe Sono , Kodande Millicent , Nalwoga Caroline , Mugaya Samuel , Onduso Pamela
Published: January 2018

While the importance of pursuing integrated population, health and environment (PHE) approaches and ensuring their sustainable expansion to regional and national levels have been widely affirmed in the development field, little practical experience and evidence exist about how this can be accomplished. This paper lays out the systematic approach to scale up developed by ExpandNet and subsequently illustrates its application in the Health of People and Environment in the Lake Victoria Basin (HoPE-LVB) project, which is an integrated PHE project implemented in Uganda and Kenya from 2012–2017. Results demonstrate not only the perceived relevance of pursuing integrated development approaches by stakeholders but also the fundamental value of systematically designing and implementing the project with focused attention to scale up, as well as the challenges involved in operationalizing commitment to integration among bureaucratic agencies deeply grounded in vertical departmental approaches.
Effects of Ionic Strength on Arsenate Adsorption at Aluminum Hydroxide–Water Interfaces
Authors: Xu Tingying , Catalano Jeffrey
Published: January 2018

Adsorption processes at mineral–water interfaces control the fate and transport of arsenic in soils and aquatic systems. Mechanistic and thermodynamic models to describe this phenomenon only consider inner-sphere complexes but recent observation of the simultaneous adsorption of inner- and outer-sphere arsenate on single crystal surfaces complicates this picture. In this study, we investigate the ionic strength-dependence of the macroscopic adsorption behavior and molecular-scale surface speciation of arsenate bound to gibbsite and bayerite. Arsenate adsorption decreases with increasing ionic strength on both minerals, with a larger effect at pH 4 than pH 7. The observed pH-dependence corresponds with a substantial decrease in surface charge at pH 7, as indicated by ζ-potential measurements. Extended X-ray absorption fine structure (EXAFS) spectroscopy finds that the number of second shell Al neighbors around arsenate is lower than that required for arsenate to occur solely as an inner-sphere surface complex. Together, these observations demonstrate that arsenate displays macroscopic and molecular-scale behavior consistent with the co-occurrence of inner- and outer-sphere surface complexes. This demonstrated that outer-sphere species can be responsible for strong adsorption of ions and suggests that environments experiencing an increase in salt content may induce arsenic release to water, especially under weakly acidic conditions.
Investment Promotion, Fiscal Competition and Economic Growth Sustainability
Authors: Wu Bin , Xu Xuefei , Feng Zhenzhong
Published: January 2018

Local governments in China build development zones to attract investment. We develop a model of fiscal competition to examine investment promotion under centralization and decentralization. Our study shows that even when perfect information is not available, under the condition of an indivisible investment, a central government achieves the optimal investment in development zones and the best tax ratio for maximizing total welfare, whereas decentralized decision-making easily results in infrastructure overinvestment and tax erosion, which does harm to economic growth sustainability.