bluuebunny/crossref_metadata_2025 huggingface dataset:
HemPHL: A Personal Health Library and mHealth Recommender to Promote Self-Management of Hemophilia
Authors: Olusanya Olufunto A. , Ammar Nariman , Brakefield Whitney S. , Crescioni Mabel , Chupka Janet , Tarver DeBran , Shaban-Nejad Arash
Published: May 2021

Hemophilia is a rare inherited bleeding disorder characterized by the blood’s inability to clot and could result in potentially life-threatening spontaneous bleeding into joints, organs, and tissues. Moreover, long-term management of this chronic disease is complex and costly. Current scientific evidence demonstrates that personalized digital health technologies could promote and facilitate the self-management of chronic diseases. This study introduces HemPHL a Personal Health Library and mHealth Recommender platform to gather, manage, and exchange tailored health information and recommendations to facilitate self-management and home therapy among individuals with hemophilia. The proposed digital health solution will adopt novel data science, artificial intelligence tools and techniques to manage and use information, as well as promote best practices for health education to enable patients to make informed decisions about their health. To accomplish this, an array of complex health and non-health information will be obtained from multi-dimensional sources to develop a secure, single access point of information for patient use. Patient’s access to personalized health information could harness their engagement and independence as well as empower them to remotely monitor their health progress and improve compliance with treatment plans. This hemophilia-focused, user-centered app can markedly improve patients’ clinical outcomes and overall quality of life.
Reusing Decisions Made with One Decision Support System to Assess a Second Decision Support System: Introducing the Notion of Complex Cases
Authors: Redjdal Akram , Bouaud Jacques , Guézennec Gilles , Gligorov Joseph , Seroussi Brigitte
Published: May 2021

The guideline-based decision support system (GL-DSS) of the DESIREE project and OncoDoc are two clinical decision support systems applied to the management of breast cancer. In order to evaluate the DESIREE GL-DSS, we decided to reuse a sample of clinical cases previously resolved by the multidisciplinary tumor board (MTB) of the Tenon Hospital (Paris, France) when using OncoDoc. Since we had two different knowledge representation models to represent clinical parameters and decisions, and two formalisms to represent guidelines, we developed a transformation sequence, involving the creation of synthetic patients, the enrichment of DESIREE ontology, and the translation of clinical cases and their decisions, to transform OncoDoc data into the DESIREE representation. Considering MTB decisions as the gold standard, the 84% compliance rate of DESIREE recommendations was rather satisfactory. Some situations (0.7%) concerned clinical cases that were compliant neither with OncoDoc nor with DESIREE that we defined as complex cases, not handled by guidelines, which necessitate effective MTB discussions.
10-Months Study Regarding the COVID-19 Spreading in Romanian Counties
Authors: Dascalu Cristina Gena , Antohe Magda Ecaterina , Purcarea Victor Lorin
Published: May 2021

The paper analyzes the evolution of COVID-19 cases in Romanian counties over a period of 10 months, to highlight possible similarities that may contribute to a better understanding of the spreading pattern. The study uses the numbers of active cases for each county in Romania, as well as Bucharest and the whole country, reported daily by the Romanian Ministry of Health (https://datelazi.ro) between April 2nd, 2020 and January 25th, 2021. We compared the disease’s evolution in Suceava county (the first outbreak of spread) with other counties in Romania in order to highlight the gaps between them. We calculated the cross-correlations between counties, interpreted as time series. The recorded lags varied between 1–15 days, the most counties having a lag of 6–7 days compared with Suceava. Therefore, on long term there are no important discrepancies between the regions in Romania regarding the evolution of the disease, which shows that the intervention efforts of the medical staff were uniform in efficiency. The existence of a lag of only one day between Suceava and the whole country shows that on long term, even in this county the situation is not very discrepant, belonging to the general evolution.
A Lean Approach to Evaluating Prescribing Errors in Medication Reconciliation
Authors: Putra Yudha , Yusof Maryati Mohd.
Published: May 2021

We evaluated medication reconciliation processes of a qualitative case study at a 1000-bed public hospital. Lean tools were applied to identify factors contributing to prescribing errors and propose process improvement. Errors were attributed to the prescriber’s skills, high workload, staff shortage, poor user attitude and rigid system function. Continuous evaluation of medication reconciliation efficiency is imperative to identify and mitigate errors and increase patient safety.
mHealth: Where Is the Potential for Aiding Informal Caregivers?
Authors: Bradway Meghan , Woldaregay Ashenafi Zebene , Issom David-Zacharie , Pfuhl Gerit , Hartvigsen Gunnar , Årsand Eirik , Henriksen André
Published: May 2021

The health and well-being of informal caregivers often take a backseat to those that they care for. While systems, technologies, and services that provide care and support for those with chronic illnesses are established and continuously improved, those that support informal caregivers are less explored. An international survey about motivations to use mHealth technologies was posted to online platforms related to chronic illnesses. We focused on responses regarding the facilitators and challenges of achieving health goals, including the use of mHealth technologies, for the subgroup who identified as “Caregivers”. Findings indicate that mHealth technology is not yet the most important motivational factor for achieving health goals in this group, but greater future potential is suggested.
The Application of a Novel, Context Specific, Remote, Usability Assessment Tool to Conduct a Pre-Redesign and Post-Redesign Usability Comparison of a Telemedicine Website
Authors: Campbell Jessica Lynn , Monkman Helen
Published: May 2021

The usability of telemedicine provider websites is an essential component of increasing the public’s awareness of, understanding of, and safe and effective use of telemedicine. A newly developed usability data collection tool was used to conduct a usability assessment of the Teladoc website pre- and post- a redesign. The results suggest that the Teladoc website had better usability prior to the redesign. The Teladoc Website Usability Survey (TWUS) developed for the Teladoc website usability assessment can be modified and used in future usability studies of telemedicine provider interfaces. Usability research that takes place in specific context of use settings is more valuable to identify usability problems.
Service Robotics in Nursing Care. The Preliminary Results of a Scoping Review
Authors: Ohneberg Christoph , Stöbich Nicole , Warmbein Angelika , Rathgeber Ivanka , Fischer Uli , Eberl Inge
Published: May 2021

A scoping review was prepared in the first study phase of the REsPonSe project. The objective was to gain an overview of existing literature and available evidence on the subject of service robotics in nursing care. The systematic literature search took place using the following databases: PubMed, CINAHL, Cochrane, Web of Science and IEEE Xplore. The titles and abstracts of 2.761 references were screened based on the inclusion criteria. A total of 31 articles were identified as relevant for the study.
Needs Survey for Health Support Application Development Project for Residents Returning from Evacuation After the Fukushima Nuclear Accident
Authors: Nakano Hironori , Goto Aya , Ohba Takashi , Yoshida Kazuki , Nollet Kenneth , Murakami Michio , Ohira Tetsuya , Kumagai Atsushi , Tanigawa Koichi
Published: May 2021

The purpose of this study was to identify the needs of stakeholders in developing a mobile application (MP) to be used by returning residents and providers of healthcare and medical/social services. The needs assessment of the residents revealed that among the elderly, ownership of smartphones and tablets was low and they were less likely to use the applications themselves.
Comparison of Knowledge Databases to Be Used in Automated Monitoring of Orthopedic Medical Devices
Authors: Dhalluin Thibault , Grammatico-Guillon Leslie , Rosset Philippe , Cuggia Marc
Published: May 2021

Surveillance and traceability of medical devices (MD) is a challenge in health care systems. In the perspective of reusing EHR data to automate the monitoring of medical devices, we carried out a comparison of the main MD knowledge bases (MD-KDB) currently available in France. Four MD-KDBs (ANSM, Gudid, Exhausmed and CIOdm) were compared quantitatively and through an example of a shoulder prosthesis. The number of MDs registered differs from one MD-KDB to another. Domain terminologies used in MD-KDBs differ in terms of granularity and in the ease of querying. Waiting EUDAMED, the European MD-KDB, it seems necessary so far to use and combine information coming from several MD-KDBs to address MD monitoring.
Promoting Positive Values while Emphasising on Aesthetical Perspectives in University Students through Adaptation of Knowles Seven Step Process of Andragogical Approach
Authors: Jiman Juhanita
Published: May 2021

This paper intends to illustrate how Knowles’ seven step process of androgogical approach can help educators to better facilitate animation students with acquired technological knowledge and skills while exposing them to critical aesthetical elements and ethical principles. It is important for educators to understand that they are dealing with young adults who are highly affected by their environments in this borderless world. Therefore, educators are responsible for more than just academics; they also have social roles. To resolve these concerns, an effective androgogical approach can be advantageous for both educators and students. We used to assume that teaching pedagogy was necessary at all levels of education; however, since university students are no longer children, pedagogical methods are not entirely relevant to them. Pedagogy is a teaching method that focuses on children, while andragogy is a teaching approach that focuses on adults and helps them learn more effectively. When people grow older, they become more self-reliant and accountable for their actions. The pedagogical model, in several ways, fails to take care for such developmental shifts, resulting in individual stress, frustration, and resistance. Due to the rapid development in technology, animation students have become highly aggressive in their pursuit of technological expertise, leading them to ignore and overlook the importance of a story's core values. As educators, we must not only help them achieve their goals in terms of technical abilities, and professional experience, but also teach them what is right and wrong, and inspire them to instil moral principles in their work
Design, Implementation and Evaluation of a Serious Game for Obesity Prevention19 among Preschool Children
Authors: Wang Yanzhen , Mohamad Yatim Maizatul Hayati
Published: May 2021

This paper presents the design, implementation and evaluation of a kindergarten based prevention on childhood obesity among preschool children. The prevention applies motivational game-based learning and behaviour change theories during design. Preschool children are the main target group for this study because preschool childhood obesity has been found correlated to obesity in later years of childhood, thus preventing and treating preschool obesity are particularly important. There have been few prevention and interventions that have targeted game based strategies in the kindergarten to promote health outcomes in preschool children and especially in Asian countries. To our knowledge, Fight Obesity 2.0is the first mobile application in Southeast Asia. In this study, it shows a positive way for the content experts and subject experts to collaborate with each other to design and develop digital mobile games for preschool children, we discuss in detail the challenges faced while designing and implementing this trial. Finally, we present the evaluation results from the three-scope validation strategy.
Enduring the Loneliness inside the Catholic Diocesan College Seminary
Authors: Naparan Genesis B. , Seminarian Clive Jarry S. Kingco  , Seminarian Arnel G. Bolivar  , Seminarian Ralph Kenneth S. Salinas
Published: May 2021

Seminarians inside the Seminary experienced many difficulties. One of them is the experience of loneliness. The present research examined the ways of enduring the loneliness inside the Seminary. The purpose of this study is to help improve the commitment in the priesthood. The researchers used a qualitative transcendental phenomenological approach in exploring the experiences of nine college seminarians. Phenomenological is an approach to qualitative research that describes the meaning of several individuals' lived experiences, which in this research talks about the seminarians' loneliness inside the Seminary. The forms of loneliness experienced by the seminarians are classified into three themes: 1) Seminary-Related Loneliness; 2) Living away from the family, and 3) Being alone. The seminarians deal with their experienced loneliness through Social Interaction, Prayer, and making the Self Busy. The results reveal that loneliness inside, although inevitable, can be prevented through prevention measures. Future researchers may conduct a further study on how to improve the seminarians' lives inside the Seminary to help the seminarians be more committed to the priesthood.
Implementasi Peraturan Gubernur Jawa Timur No. 27 Tahun 2016 Tentang Tarif Angkutan Penumpang pada Dinas Perhubungan Propinsi Jawa Timur
Authors: Adiwidjaja Ignatius
Published: May 2021

Transportasi dan angkutan umum merupakan suatu persoalan yang selalu dihadapi oleh pemerintah di berbagai daerah di tanah air ini, terutama daerah yang memiliki suasana kota yang yang ramai karena  padatnya penduduk serta tingginya intensitas masyarakatnya diikuti dengan tidak sesuainya jumlah moda transportasi umum serta belum seimbangnya luas ruas jalan antar kota dalam propinsi yang  mempunyai struktur serta aktifitas penduduk sudah tergolong sagat tinggi. Regulasi kebijakan pemerintah propinsi Jawa Timur yang tertuang dalam Peraturan Gubernur Jawa Timur No. 27 Tahun 2016. Dinas perhubungan sebagai implementor, melakukan sosialisasi kepada masyarakat, serta menyediakan sarana sebagai pendukung dalam system transportasi di Jawa Timur. Dalam penelitian ini kami menggunakan metode kualitatif yang menghasilkan gambaran (deskripsi) mengenai hal-hal yang berkaitan dengan apa yang diteliti. Kualitatif sendiri merupakan wujud kata-kata dari pada deretan angka-angka. Pendekatan metode deskriptif dapat diartikan sebagai pemecahan masalah dengan menggambarkan atau melukiskan keadaan subjek atau objek penelitian, baik perilaku individu, kelompok masyarakat, lembaga-lembaga dan lain-lain sebagainya.Kata kunci : Implementasi, Pelayanan PublikABSTRACT. Public transportation and transportation is a problem that is always faced by the government in various regions in this country, especially areas that have a bustling city atmosphere due to overcrowding and high intensity of the community followed by mismatching the number of modes of public transportation and the imbalance of the size of roads inter-city in the province which has a structure and activity of the population is already classified as very high. East Java provincial government policy regulations contained in East Java Governor Regulation No. 27 of 2016. Transportation Agency as an implementor, conducts socialization to the community, and provides facilities as a support in the transportation system in East Java. In this study we used a qualitative method that produced a description (description) of matters relating to what was studied. Qualitative itself is a form of words rather than a row of numbers. Descriptive method approach can be interpreted as problem solving by describing or describing the state of the subject or object of research, both the behavior of individuals, community groups, institutions and so forth.Keywords: Implementation, Public Services
Integração ensino-serviço: Vivenciando na prática as campanhas de vacina em um Distrito de Saúde no município de Belém
Authors: Santos Francisca Elissandra Ribeiro dos , Souza Hilma Solange Lopes , Valentim Cíntia Yolette Urbano Pauxis Aben-Athar , Parente Andressa Tavares , Sampaio Jonathan Douglas Pinheiro , Araújo Maira Roberta Ribeiro , Palheta Marléa Guimarães , Dias Alana Celeste Campos
Published: May 2021

O objetivo do presente artigo é descrever a integração ensino-serviço vivenciada por enfermeira residente durante a campanha de vacina nas escolas, no município de Belém-PA. Metodologia: Trata-se de um estudo descritivo com abordagem qualitativa do tipo relato de experiência, vivenciada durante as atividades do Programa de Residência Multiprofissional em Atenção à Clínica Integrada, Universidade Federal do Pará, em campanha de vacina nas escolas de um Distrito de Saúde, no período de fevereiro a maio de 2019. Resultados: Foram administradas vacinas contra o HPV e Meningite C, em média de 850 e 700 doses, respectivamente. A integração do enfermeiro residente neste cenário foi bastante efetiva, proporcionando ao residente vivenciar na prática, um dos programas do Sistema Único de Saúde. Conclusão: Desta maneira, a integração do ensino-serviço, na residência, representa um importante instrumento para a construção e troca de saberes entre residentes e profissionais que atuam nos campos de prática, pois possibilita experiências inovadoras no processo ensino-aprendizagem e, consequentemente, na qualidade da formação profissional, o qual impactará diretamente na melhoria da qualidade na assistência.
Cross-Cultural Encounters: A Feminist Perspective on the Contemporary Reception of Jane Austen in China
Authors: Sun Shuo
Published: May 2021

This article examines the changing nature of Austen's reception in China since the 1950s, in particular the growth of feminist critical approaches to her work among contemporary Chinese scholars. Among Austen's works, Pride and Prejudice has remained at the centre of scholarly and popular attention and has had a major impact on Chinese readers’ view of Austen as a feminist writer. Anglo-American scholarship commonly considers Austen's feminism in relation with her contemporary Mary Wollstonecraft's feminist thought. Unfamiliar with Wollstonecraft, Chinese scholars and general readers tend to read Austen rather differently, and their exploration of her engagement with ‘the woman question’ is instead closely connected with the development of Marxism and gender studies in contemporary China.
DEPTOR in Skeletal Development and Diseases
Authors: Perez-Tejeiro Jose Miguel , Csukasi Fabiana
Published: May 2021

Discovered in 2009, the DEP-domain containing mTOR-interacting protein, DEPTOR, is a known regulator of the mechanistic target of rapamycin (mTOR), an evolutionarily conserved kinase that regulates diverse cellular processes in response to environmental stimuli. DEPTOR was originally identified as a negative regulator of mTOR complexes 1 (mTORC1) and 2 (mTORC2). However, recent discoveries have started to unravel the roles of DEPTOR in mTOR-independent responses. In the past few years, mTOR emerged as an important regulator of skeletal development, growth, and homeostasis; the dysregulation of its activity contributes to the development of several skeletal diseases, both chronic and genetic. Even more recently, several groups have reported on the relevance of DEPTOR in skeletal biology through its action on mTOR-dependent and mTOR-independent pathways. In this review, we summarize the current understanding of DEPTOR in skeletal development and disease.
Supplemental Information: The Reference Model is a Multi-Scale Ensemble Model of COVID-19
Authors: Barhak Jacob
Published: May 2021

The COVID-19 pandemic has accelerated research worldwide and resulted in a large number of computational models and initiatives. Models were mostly aimed at forecast and resulted in different predictions partially since models were based on different assumptions. In fact the idea that a computational model is just an assumption attempting to explain a phenomenon has not been sufficiently explored. Moreover, the ability to combine models has not been fully realized. The Reference Model for disease progression was performing this task for years for diabetes models and recently started modeling COVID-19. The Reference Model is an ensemble of models that is optimized to fit observed disease phenomenon. The ensemble has the ability to include model components from different sources that compete and cooperate. The recent advance in this model is the ability to include models calculated in different scales, making the model the first known multi-scale ensemble model. This manuscript will review these capabilities and show how multiple models can improve our ability to comprehend the COVID-19 pandemic.
Desarrollo de habilidades socioemocionales a través de un curso de tutorías B-Learning para alumnos de nivel Bachillerato de la Universidad Autónoma de Zacatecas “Francisco García Salinas”: Estudio realizado en el Programa de Preparatoria No. XIII
Authors: Hernández-Larios Martha Susana , García-Villalobos Alejandro Rodolfo , Barrios-García Esmelda , Hernández-Berumen José de Jesús
Published: May 2021

As part of the institutional strategy to prevent failure and school dropout, seeking better academic performance by upper-secondary students, a project is established where the tutorial part is related to the use of technological tools and resources. A course in B-Learning is developed, developing strategies that modify their behavior and performance, said course consists of four units, where strategies are developed to improve attention, identify emotions and the strategies necessary for their concentration, allowing them to develop social-emotional skills achieving better academic performance.
Violencia escolar y calidad de vida relacionada con la salud en niños de escuelas primarias
Authors: García-García Jesús Alberto , Osornia-Ramón Larissa , Ramírez-Cerecero José Ricardo , Morán-Delgado Gabriela
Published: May 2021

The objective of this article is to analyze the dimensions of school violence and its impact on the health-related quality of life of primary school children at social risk in the city of Saltillo, Coahuila. The methodology used is quantitative, observational, cross-sectional, prospective and descriptive. The information was collected through two instruments, CUVE3-EP to measure School Violence and KIDSCREEN-27 for Health-Related Quality of Life, where 416 children aged 5 and 6 were taken as a sample. Primary education. The sampling method used is convenience sampling. The statistical techniques used were descriptive, correlational and comparative. The contribution of the study starts from the identification of the different types of school violence and its association with the quality of life of primary school children. Being verbal violence between students a factor that decreases psychological well-being, as well as their autonomy and relationship with parents.
The Effectiveness of Intellectual Property Rights Protection to Improve Creative Economy Realization in Semarang District
Authors: Mashdurohatun Anis , Yuliawan Indra , Susilo Adhi Budi , Laksamana Andri Winjaya , Mansyur M. Ali
Published: May 2021

Law No. 24 of 2019 concerning the creative economy states that wealth is a cultural heritage that needs to be utilized. It further becomes a product that creates added value where the Government and Local Government are responsible for creating and developing a creative economy ecosystem. Even though it is legalized in regulations, the management of Intellectual Property Rights in the Regency Semarang is still minimal. The research objectives are to study and analyze the effectiveness of protection of intellectual property rights as a driving force for the creative economy and formulate the ideal role of the Semarang district government in encouraging the realization of the creative economy. The juridical-empirical research method used primary data. The results of this study are that the protection of intellectual property rights as a driving force for the creative economy has not been effective. The number of registered brands from 2018-2020 is 174, which is not comparable to the number of MSME management industries in Semarang Regency. The people still have low legal awareness, lack of business capital, and little knowledge of the community's intellectual property. The ideal government of the Semarang district in encouraging the realization of the creative economy has four fields: the formation of regulations, managing the legality of MSMEs, access to business capital, management, and the MSMEs market.
A REVIEW ON THE CHALLENGES FACED ON REGULAR BLOOD SUPPLY POST COVID - 19 VACCINATION AND THE NECESSITY TO IMPLEMENT AN ACTIVE PATIENT BLOOD MANAGEMENT PROGRAMME
Authors: Mani Anila , Kumar I S Chaitanya
Published: May 2021

As Covid-19 vaccines are being distributed throughout the nation, there has been increased concern regarding the deferral period for blood
donation. There are no uniform deferral criteria across the globe till date and the deferral period in some countries depend upon the type of Covid-19
vaccine being administered. Deferral period post-vaccination has impacted on the number of eligible blood donors available to donate blood which
can eventually result in shortage of blood and blood components. An imbalance between the availability and demand of blood supplies can
ultimately lead to adverse outcomes in the health care system. Hence, it is imperative to promote autologous blood donation programmes to attain
an active patient blood management strategy nationwide so as to reduce the impact of allogenic blood shortage and risks of allogenic blood
transfusion.
EFFECTIVENESS OF AN EDUCATIONAL PROGRAM ABOUT BREAST CANCER AND BREAST CANCER SELF-EXAMINATION ON PERCEPTION AND PRACTICE AMONG WOMEN IN ALJEERAIF WEST ADMINISTRATIVE UNIT (2)
Authors: Elagib Amel Eltaib , Mohammed Ibrahim Ismail , Idris SamiaYousif , Abdelrahman Omar Jaafar , Babiker Somia Bilal , Mohammed Isra khalil
Published: May 2021

In Sudan, cancer incidence has been growing considerably in recent years and is likely to continue to grow creating a big burden on the health system resources. The aim of this study is to assess the baseline Perception and Practice about breast cancer and breast self-examination (BSE) and to nd out the effectiveness of an educational program about breast cancer and BSE on Perception and Practice among women in AlJeeraif West Administrative Unit. Community based intervention study with pre-post and control was carried out among 200 women who were recruited by means of multistage sampling. The sample size was divided equally into intervention and control groups. Baseline data was collected from both groups through direct interview, using structured close ended questionnaire. Educational program was implemented for the intervention group. Four months after the intervention, women in the study and control groups were exposed to the same questionnaire. Chi-square, paired t-test and independent t-test (difference of difference) were conducted in the course of the data analyses. There was statistically signicant difference in the intervention group pre-post program in all of the HBM components in the intervention group (p value0.000), while in the control group statistically signicant difference existed only in perceived barrier (p value.004) and perceived benet (p value.000) and over all perception (p value .016) with no signicant difference in other (HBM) components. In the intervention group practice and performance scores were highly signicant pre-post program (p value 0.000), where as in the control group only practice was signicant (p value 0.001). There were statistically signicant differences in the mean difference of performance, practice and perceptions between the intervention and control groups (p-value .000). The results of this study have conrmed the effectiveness of educational program based on the health belief model on improving perceptions and practice of breast cancer and breast self-examination.
ASSOCIATION OF IRON DEFICIENCY ANEMIAAND POST CRICOID WEBS – A PROSPECTIVE STUDY
Authors: Somu L. , Cheruvu Saranya Chithra , Manimaran Vinoth
Published: May 2021

Iron deciency anemia, post-cricoidal esophageal web and dysphagia are characteristics of Patterson Brown Kelly or Plummer-Vinson syndrome.
Sideropenic dysphagia was coined by Waldenstorm. There has been a debate regarding the existence and frequency of esophageal webs in patients
with iron deciency anemia.In, literature there is no study that correlates the severity of anemia and severity of the web or stricture.This is a
prospective study of 50 patients over a period of 3 years. Through our study we would like to analyse if there is any corelationship especially in
developing countries like ours were this study was conducted.
FACTORS AFFECTING INTENSIVE CARE AND MORTALITY IN SARS-CoV 2019 HOSPITAL PATIENTS
Authors: Uzan Gulfidan , Kar Bedriye , Karakas Evren Canel , Koldas Macit , Sonmez Mehmet Mesut
Published: May 2021

Backround: Information on prognosis and treatment in COVID-19 is limited and variable. We wanted to report the demographic, clinical,
laboratory, radiological data and treatment and follow-up results of our patients diagnosed with COVID-19 in the study and to determine the factors
affecting prognosis and mortality. Materials-methods: The study included 1161 inpatients with PCR positive and/or radiologically diagnosed
COVID-19 pneumonia. Of these, 151 patients were taken to the intensive care unit and 37 patients were intubated. The data obtained through the
system were evaluated retrospectively and observationally. Results: The mean age of 1161 inpatients was 54.5 years and 616 (53.1%) were male.
104 (8.9%) of 1161 inpatients died. 151 (13%) were taken to the intensive care unit. Of these, 37 (24.5%) were intubated. The analysis revealed
age(p<0.001), gender(p<0.001), presence of comorbid disease (p<0.001), cough(p<0.001), shortness of breath (p<0.001), fatigue and malaise
symptoms (p<0.001) and in the laboratory and signicant correlation was found with some laboratory parameters and some treatment options
(p<0.001).When the living and deceased patients were compared; age (p<0.001), gender(p=0.001), presence of additional disease (p<0.001),
cough(p<0.001), shortness of breath (p<0.001), malaise and fatigue symptoms (p<0.001), in the laboratory; signicant correlation was found with
some laboratory parameters and some treatment options (p<0.001).Conclusion: We believe that these data obtained in our study will be important
in predicting prognosis and mortality and in effective patient management. We wanted to emphasize that hydroxychloroquine, favipravir,
methylprednisolone and enoxoparin are effective in reducing mortality in the treatment.
Dalbavancin in the treatment of patients with Gram-positive diabetic foot infection: a case report
Authors: Stroffolini, G.
Published: May 2021

Dalbavancin is a potent lipoglycopeptide active against Gram+ bacteria with a favorable pharmacokinetic/pharmacodynamic (PK/PD) and safe­ty profile, suitable for numerous challenging infections. Dalbavancin has been approved for ABSSSIs, but its range of application and the relative posology is still debated. Diabetic foot infections are a major challenge and a leading source of complications, involving high direct and indirect costs for healthcare systems and for patients in terms of morbidity and disability. Gram+ bacteria are often causative agents in diabetic foot infections. We discuss here the case of a 43 yars old patient with complicated diabetic foot infection and the successful application of a dalbavancin secondary monotherapy treatment protocol. The patient, after suffering a two months complex hospitalisation gained wound haeling and limb rescue without any complication. We were also able to measures dalbavancin plasma lev­els determining its long half-life and high microbial killing ability. KEY WORDS dalbavancin, diabetic foot, gram-positive.
Heart failure therapy in patients with diabetes
Authors: Tuccinardi, F.
Published: May 2021

The great interest in the problem “Heart failure” (HF) by the diabetolo­gist has been born in recent years and is mainly linked to the availabil­ity of new antidiabetic drugs which have shown a significant benefit in reducing hospitalizations for heart failure and cardiovascular mortality. Diabetes patients have more than double the risk of developing HF compared to patients without diabetes. The Framingham study has shown that diabetes increases the risk of heart failure up to 2 times in men and 5 times in women compared to controls over age. In addition, 12% of patients with DMT2 have heart failure and 30% of patients with heart failure are diabetic. Hospitalization for HF is associated with very high rates of both post-dis­charge mortality and new hospitalizations. Readmission rates for clinically stable patients discharged after recent hospitalization for HF are approximately 25% at 6 months and all-cause mortality exceeds 30% at 1 year. In particular, a worse prognosis and a longer hospital stay are associated with hospitalized diabetes patients. There is a close correlation between metabolic compensation and HF. In fact, in patients with diabetes a 1% increase in HbA1c is associated with an 8% increase in the risk of HF and still the improvement of the glycometabolic control reduces the risk of HF (in the UKPDS the 1% re­duction in HbA1c was associated with a 16% reduction in the risk of HF occurring). KEY WORDS T2DM; heart failure; SGLT2-inhibitors; diabetic cardiomyopathy.
Insulin DEgludec in hospitalized patients with type 2 diabetes (IDEOS Study): what effects on glycemic control, glycemic variability and hypoglycemia
Authors: Ponzani, P.
Published: May 2021

Modern guidelines suggest the control of hyperglycemia in hospitalized patients through insulin therapy and the achievement of individualized glycemic targets, avoiding hypoglycemia, associated with a worsening of outcomes and a mortality increase. There is little evidence in literature on the use of new basal insulins in a hospital setting. OBJECTIVE OF THE STUDY Document, in real life context, the use of insulin degludec and the results in terms of glycemic control, variability and hypoglycemia in hospitalized patients with type 2 diabetes, com pared to a population treated with traditional basal insulins. DESIGN AND METHODS Prospective observational study on patients hospitalized in internist area. Personal and clinical data, in particular capillary blood levels on 4 daily points and hypoglycemia were collect ed. In a group of patients on traditional basal insulin therapy not at tar get, a switch to insulin degludec was performed. RESULTS 65 patients (58.5% male) were enrolled: age 70.8±10.7 years, BMI 27.7 ± 4.4, HbA1c 8.4 ± 1.3% (average+/SD). 76.4% of patients had 3 or more comorbidities. 69.2% of patients were treated with basalbolus, 7.7% with basalplus, 16.9% with basal insulin alone. In the group treated with degludec (35 patients), a significant reduction in mean capillary glycaemia was obtained between the first day of hospitaliza tion or initiation of therapy and discharge in each time slot: 36.6 mg /dl fasting (p <0.0001), 30 mg/dl before lunch (p <0.005), 38.9 mg/dl before dinner (p <0.001) and 37.3 mg/dl bedtime (p <0.001) and also fewer hypoglycemia (20% had at least one daytime hypoglycemia, no subjects had nocturnal hypoglycaemia). In the group receiving insulin glargine for the entire period (30 patients), a significant reduction in capillary blood sugar levels is present only in the pre lunch range (43.8 mg / dl, p <0.001) and 26% of subjects had at least one daytime hypoglycemia and 2% nocturnal hypoglycemia. In the group switched to degludec, the mean capillary fasting blood glucose decreased from 176.6 ± 27.9 to 130.4 ± 36.6 mg/dl, that of predinner from 217.9 ± 36.7 to 170.9 ± 49.1 mg/dl, patients at target upon awakening increased from 10% to 65%, glycemic variability expressed as the mean of morning standard deviations fell from 45.2 to 25.6 and hypoglycemia decreased (% of patients with at least one daytime hypoglycemia from 25% to 15%, with nocturnal hypoglycemia from 5% to 0%). Conclusions The use of insulin degludec in hospitalized patients in medical area was effective and safe, with better glycemic control in every time slot, fewer hypoglycemia and reduced glycemic variability. KEY WORDS basal insulins; hospitalized patients; hypoglycemia; glycemic variability.
Improvement of LoRa Communication Scalability using Machine Learning Based Adaptiveness
Authors: Valach Alexander , Macko Dominik
Published: May 2021

Number of embedded devices connected to the Internet is rapidly increasing, especially in the era of the Internet of Things (IoT). The growing number of IoT devices communicating wirelessly causes a communication-parameters selection problem, implying the increasing number of communication collisions. Multiple factors of IoT networks signify this problem, such as inability to communication-channel listening prior to the transmission (due to longer distances), energy constrains (due to inability of powering devices from the grid), or limitation of duty cycle and high interference (due to usage of unlicensed band in communication technologies). This article is focused on alleviating this problem in LoRa networks, which is one of the most promising technology for long-range and low-power

communication. We utilize the existing LoRa@FIIT protocol to achieve energy-efficient communication. The scalability of the LoRa network is increased by modifying the communication-parameters selection algorithm. By ensuring of quality of service mechanism at each node in the infrastructure, the application domain of the proposed architecture is widened. The simulation-based experimental results showed a significantly reduced number of collisions for mobile nodes, which reduces the channel congestion and the wasted energy by retransmissions.
“Mogok” Sekolah dan Pengembangan Kecerdasan Anak Usia Dini
Authors: Yuliana Yuliana
Published: May 2021

Tujuaan penelitian ini untuk mengetahui dan menganalisis penyebab dan cara menangani anak mengalami mogok sekolah. Metode yang digunakan dalam penelitian ini ialah Literature Review. Dalam artikel ini data diperoleh dari mengkaji beberapa sumber teori terkait mogok sekolah dan pengembangan kecerdasan anak usia dini serta pengamatan langsung di TKIT Alief Mardhiyah. Kemudian dianalisis melalui beberapa tahapan yaitu perencanaan, pengorganisasian, Drafting, Editting dan Redrafting. Berdasarkan hasil kajian literatur, diketahui ada beberapa hal yang dapat dilakukan untuk dapat menangani anak yang mengalami mogok sekolah antara lain perhatikan kondisi anak-anak sebelum tidur, pahami minat-bakat anak, memotivasi anak dengan hal-hal yang disukainya, orang tua tidak mengomel berkepanjangan, ciptakan rasa aman pada anak serta meningkatkan kerjasama antara orang tua dan sekolah.
Impostor Scams
Authors: Friedman David
Published: May 2021

Impostor scams have recently become the most common type of consumer scam in America, surpassing identity theft. It has never been easier and more profitable to be an impostor scammer. Though the core of these scams dates back centuries, these fraudsters consistently find novel ways to manipulate human motives and emotions. Nonetheless, the public should not give up hope. Policymakers and private actors can slow down this scourge if they focus on the key chokepoints that impostor scammers rely upon to achieve their ends. This Article provides a roadmap for a solution to impostor scams, offering specific suggestions for mitigating this fraud today, while advocating the adoption of a “least-cost avoider” approach to address the whole of the ongoing problem.
ЯЙЦЕНОСКОСТЬ КУР-НЕСУШЕК ПРИ ИСПОЛЬЗОВАНИИ ФЕРМЕНТНЫХ ПРЕПАРАТОВ В РАЦИОНЕ КОРМЛЕНИЯ
Authors: Ибрагимов М.О.
Published: May 2021

При использовании ферментных препаратов Санзайм и Санфайз 5000 повысились продуктивные показатели кур-несушек. Яйценоскость в расчете на начальную несушку повысилась на 4,9%, на среднюю несушку на 4,3%, интенсивность яйцекладки на 3,7 %. Это позволило получить в опытных группах на 4,5 –7,3% больше яичной массы по сравнению с контрольной группой.
ВАЖНЫЕ ВЕХИ В РОССИЙСКО-ЧЕЧЕНСКИХ ОТНОШЕНИЯХ В ХVI – ХVIII вв.
Authors: Гапуров Ш.А. , Сугаипова А.М.
Published: May 2021

В работе рассмотрены основные этапы российско-чеченских отношений в ХVI – ХVIII вв. Отмечается, что в конце ХVI века в Москву отправляется первое чеченское посольство, и с 1589 года, согласно царской грамоте, чеченцы считаются в российском подданстве. Фактически с этого времени установился российско-чеченский военно-политический союз, переросший к концу ХVIII века в российско-чеченское государственное единство.
A felosztási diplomácia gyakorlata és a hatalmi egyensúly kérdése Lengyelország XVIII. századi példáján keresztül : Az első lengyel felosztás kortárs angol politikai ikonográfiája (1772-1774)
Authors: Schvéd Brigitta Kinga
Published: May 2021

Poroszország, Oroszország és Ausztria 1772-ben sikeresen kezdte meg a lengyel–litván nemzetközösség területének egymás közötti felosztását, majd a három közép-kelet-európai hatalom új típusú felosztási diplomáciai gyakorlatának következtében a harmadik felosztást követően, 1795-re Lengyelország hosszú időre eltűnt Európa térképéről. A felosztásokra tárgyalóasztalok mellett, diplomáciai egyezmények révén került sor anélkül, hogy bármelyik szomszédos nagyhatalom háborúba keveredett volna egymással, avagy Lengyelországgal. A kortárs nyugat-európai diplomaták főként az európai hatalmi egyensúly alakulásának szempontjából vizsgálták az eseménysorozatot, tartva a három közép-kelet-európai hatalom inváziójának nagyhatalmi következményeitől. Már a kortárs visszhangok zöme is úgy vélte, hogy Lengyelország felosztásaiban egy újfajta egyensúlyozó politika, egy felosztási diplomáciára épített hatalomgyakorlat öltött testet. Jelen tanulmány ennek a sajátosan egyensúlyozó, felosztási diplomáciára épített nagyhatalmi konstellációnak a gyökereit kívánja vizsgálni egy sajátos aspektusból, elemezve az első lengyel felosztáshoz (1772) vezető bel- és külpolitikai utat, mindemellett bemutatva az európai hatalmi egyensúlyban különösen érdekelt Nagy-Britannia véleményét Lengyelország feldarabolásáról. A tanulmány fő része az első felosztásról szóló különböző brit vélemények vizualitását elemzi. A felosztásra reflektáló, közvetett vagy közvetlen módon ahhoz kapcsolódó kortárs brit politikai metszetek tekintetében öt grafika kerül részletes politikai ikonográfiai elemzésre a British Museum gyűjteményéből az 1772–1774 közötti időszakból.
Стан пенсійного забезпечення військовослужбовців і членів їхніх сімей
Authors: Андрейчук С. К. , Морушко О. О. , Гасяк М. С.
Published: May 2021

Проаналізовано стан пенсійного забезпечення військовослужбовців і членів їх сімей та осіб, звільнених з військової служби, в Україні та можливості адаптації зарубіжного досвіду до вітчизняних умов. Тема реформування пенсійної системи України є однією з найболючіших та найактуальніших тем останніх десятиліть. Відновлення справедливості у визначенні пенсійних виплат є основною метою всіх кроків пенсійної реформи. Водночас, пенсійне забезпечення є однією з найбільших проблем державної політики ХХІ ст. не тільки в Україні. Саме тому аналіз набутого досвіду реформ інших країн може дати змогу уникнути багатьох проблемних моментів реформування та допомогти виокремити основні найефективніші кроки процесу трансформації пенсійної системи України. Предметом цього дослідження є пенсійне забезпечення військовослужбовців. Адже останні роки затяжного збройного конфлікту на Сході України актуалізували питання соціальної захищеності саме категорії військовослужбовців і членів їхніх сімей. Вирішення цих питань пришвидшить темп становлення стандартів соціального захисту військових Збройних Сил України. Розглянуто соціальний захист військовослужбовців як діяльність держави у сфері соціальної політики, яка спрямована на забезпечення гідного рівня життя для військовослужбовців та членів їхніх сімей. Описано багаторівневу ієрархію системи соціального захисту військовослужбовців Збройних Сил України. Проаналізовано функції Міністерств та інституцій, які забезпечують функціонування системи соціального захисту військовослужбовців загалом. Здійснено аналіз видів пенсійного забезпечення, на які мають право особи, звільнен і з військової служби в нашій країні. Розмір пенсійних виплат та інших видів грошового забезпечення є базою для нарахування пенсій військовослужбовцям нашої держави. Актуальним завданням реалізації пенсійної реформи є уникнення "зрівнялівки" у розмірах пенсій різних категорій населення. У разі нарахування пенсій військовослужбовцям перерахунок пенсій здійснюють з порушеннями, зокрема ігноруючи певні складові грошового забезпечення, а саме: оплату за науковий ступінь, оплату за вчене звання та низку надбавок, серед яких надбавки за спортивні звання, за почесні звання та за виконання певних спеціальних функцій у межах службових повноважень. Одним із кроків поліпшення ефективності механізму соціального захисту є вивчення, аналіз та переймання досвіду аналогічної роботи закордонних інституцій. Для визначення шляхів реформування пенсійного забезпечення військовослужбовців здійснено порівняння аналогічного досвіду пенсійного забезпечення військовослужбовців і членів їхніх сімей на приклад і провідних країн – членів НАТО (США, Великобританії, Франції). Вибір цих країн зумовлений тим, що реформування вітчизняної системи пенсійного забезпечення військовослужбовців у пострадянській Україні багато в чому ґрунтується на запозиченні досвіду названих країн. Зроблені висновки містять рекомендації щодо рефорування системи пенсійного забезпечення військовослужбовців України.
Проектування системи управління коштами благодійного фонду
Authors: Корнак О. О. , Грицюк Ю. І.
Published: May 2021

Спроектовано систему управління коштами благодійного фонду, яка забезпечить взаємодію учасників процесу в окремій інформаційній системі задля надання їм актуальної, достовірної та цілісної інформації на етапах отримання коштів, їх розподілу та аналізу використання. З'ясовано, що відповідна інформаційна система для організації благодійного процесу має містити методи і способи збору, нагромадження, реєстрації, передавання, відображення, зберігання, пошуку, модифікації, аналізу, захисту та видачі необхідної інформації всім зацікавленим сторонам. Проаналізовано найпопулярніші сайти та платформи України для роботи благодійних фондів, що допомогло краще зрозуміти функціональність системи управління коштами організації та їх основного призначення. Визначено основне архітектурне рішення, яке використано для побудови веб-додатку, а саме – шаблон MVC, який застосовують як для проектування архітектури програмного засобу, так і для його розроблення. Побудовано діаграму варіантів використання системи управління коштами, що показує усіх користувачів системи, а також ту її функціональність, доступ до якої має відповідний клас користувачів. Для відображення динамічної роботи веб-додатку було побудовано діаграму послідовності, яка відтворює процес виділення коштів з бюджету фонду для лікування нужденних осіб. Спроектовано базу даних веб-додатку, яка передбачає виконання таких етапів: проектування на концептуальному рівні з використання ER-моделі; проектування на логічному рівні, внаслідок якої було побудовано реляційну базу даних; проектування на фізичному рівні в межах відповідної СУБД, для якої було розроблено відповідну базу даних. Розроблено графічний інтерфейс користувача: головні його елементи згідно з відомими принципами їх побудови; визначено загальну структуру та основне сприйняття його вигляду. На підставі запропонованих рішень розроблено усі інші компоненти, необхідні для роботи веб-додатку, графічні елементи та сторінки.