bluuebunny/crossref_metadata_2025 huggingface dataset:
Deciduoid Mesothelioma of Peritoneum Masquerading as Peritoneal Carcinomatosis.
Authors: Bharti Jyotsna Naresh , Vishnoi Jeewan Ram
Published: November 2021

Mesothelioma is an insidious neoplasm that develops from mesothelial cells. About 80 % of mesotheliomas originate in the pleural cavity. Other sites where it has been reported are the peritoneal cavity, tunica vaginalis, and the pericardium. A 45-year-old female presented with complaints of abdominal distention and pain for three months. Physical examination revealed signs of wasting of the appendicular and axial skeleton muscles, loss of subcutaneous fat, and hollowing of the eye sockets. There was pitting edema in the bilateral lower limbs. Per abdomen, examination revealed abdominal distension with umbilicus in the midline. On palpation, gross ascites was present, and no organomegaly, definitive mass, or lump was palpable. On percussion, the dull note was heard all over the abdomen, and fluid thrill was appreciated. The ascitic fluid examination revealed the presence of atypical cells. Omentectomy was done and sent for histopathological examination.The specimen of omentectomy was in multiple fragments and measured 17x16x3cm. Few of the fragments were nodular, soft to firm. On serial slicing, the cut section was gray-white with areas of necrosis. Microscopic examination showed sheets of malignant cells. These tumor cells were immunoreactive to EMA, Cytokeratin, Vimentin, Calretinin, WT-1, and D2-40 and immunonegative to Desmin (highlighting only the entrapped reactive mesothelial cells), Inhibin, BerEP4, TTF-1, CD 68, Napsin, ER, CEA, CDX2, PR, PAX-8, and SALL4. Ki 67 labelling index was 15%. The features were of Malignant Mesothelioma, Deciduoid variant. Deciduoid mesothelioma is a rare subtype with a poor prognosis. So, the mesothelioma should be distinguished from deciduosis.
Jack, Master or Both? The Invasive Ladybird Harmonia Axyridis Outperforms Its Native Counterpart Despite Similar Levels of Plasticity
Authors: Minnaar Ingrid Ané , Hui Cang , Clusella-Trullas Susana
Published: November 2021

The authors have requested that this preprint be removed from Research Square.
Prehatching Temperatures Drive Interannual Cohort Differences In Great Tit Metabolism
Authors: Broggi Juli , Hohtola Esa , Koivula Kari , Rytkönen Seppo , Nilsson Jan-Åke
Published: November 2021

Basal metabolic rate (BMR) constitutes the lowest metabolic rate in a resting animal and is therefore considered to reflect the energetic cost of maintenance in endotherms. BMR is a reversible plastic trait that changes with environmental and ecological circumstances, albeit being heritable and susceptible to selection. Inter-individual variation within populations of small birds is substantial, and while many of the drivers of such variation have been identified, many remain unexplained. Some of the variation can be ascribed to cohort effects, indicating non-reversible developmental plasticity that will shape the adult metabolic phenotype. We studied winter BMR variation of juveniles over a fifteen-year period in a wild population of great tits Parus major at the northern border of their distribution. Here we show for the first time that winter BMR in cohorts of great tits changes among winters as a response to minimum ambient temperatures experienced early in life, during the prehatching period. This developmental plasticity might be adaptive if temperatures experienced by growing embryos would metabolically prime them to an environment that they will likely encounter in future life. However, in line with a more unpredictable future climate, the risk of phenotype-environment mismatch is likely to lead to certain cohorts being poorly adapted to prevailing winter conditions, resulting in wider annual fluctuations in population size.
Genetic Diversity and Population Structure in Wild Seabuckthorn (Hippophae Salicifolia) Growing in the Uttarakhand Region of The Indian Himalayas
Authors: Chaudhary Parneeta , Sharma Prakash Chand
Published: November 2021

Seabuckthorn (Hippophae salicifolia) is an economically important dioecious and deciduous actinorhizal tree species. Considering the contemporary interest in seabuckthorn as a future multipurpose crop, efforts have been initiated towards an assessment of genetic diversity prevailing in the natural populations inhabiting diverse geographical areas. In the present study, morphological and molecular diversity was studied in Hippophae salicifolia representing diverse ecological sites in the different geographical areas of the Garhwal and Kumaon regions of Uttarakhand, India. Morphological diversity was assessed by studying a total of twenty-seven morphological characters. For standard identification of the color of leaves and berries, a color-coded reference (RHS)-based study was also performed. By employing fifteen microsatellite markers, we observed 109 alleles, with 71.5% markers being polymorphic. Furthermore, Polymorphic Information Content (0.387), expected heterozygosity (He)/ Nei’s Diversity (0.641), Wright’s fixation index (Fis) (0.630), and Shannon’s informative index (I) (0.646) among the four populations were calculated simultaneously to study the phylogenetic relationship. The UPGMA-based dendrograms were also prepared by using morphological and molecular data. The dendrograms showed a demarcation between collections from different regions, although a few collections were found clustered with collections from the other regions. Assessment of genetic diversity was efficient and more informative using microsatellite markers. The findings of this study will be useful in future breeding and conservation programs in Hippophae salicifolia and related species.
The copy quantities of TRECs as a biomarker for screening SCID in newborns：a meta-analysis
Authors: Li Bihan , Sun Zhiyong , Liu Ying , Song Jinxia , Wang Lijuan , Li Gaokai , Liu Ying , Sun Shilong
Published: November 2021

Purpose

Severe combined immunodeficiency (SCID) threatens the newborns' living qualities. The aim of our study is to evaluate the the value of detecting the copy quantities of T-cell receptor excision circles (TRECs) in screening for the newborns' SCID.
Methods

We searched eligible studies in PubMed, Web of science, EMBASE, the Cochrane Library, China National Knowledge Infrastructure (CNKI) and chose the Endnote software to filter the whole studies. Meta-analysis was conducted with meta-disc 1.4 and STATA 12.0 software. We used sensitivity and false positive rate (FPR) to evaluate this detecting method; subgroup analysis to explore the sources of heterogeneity. The literature quality was assessed by the quality assessment of diagnostic accuracy studies (QUADAS-Ⅱ).
Results

Fifteen studies were enrolled containing 3,570 cases in the decreased TREC copy quantities group and 12,186,899 cases in control group. All the included studies are of high quality. The heterogeneity in Diagnostic Odds Ratio (DOR) is 77.9%. The summarized estimates revealed that the pooled sensitivity is 100% (95% confidence interval (CI): 99–100%), the false positive rate is 0.00 (95% CI: 0.00–0.00) and Positive Predict Value (PPV) is 0.14 (95% CI: 0.08-0.19). The current evidence shows detecting the copy quantities of TRECs has the screening value with a high sensitivity and positive likelihood ratio (LR+) for newborns' SCID without published bias (p>0.05). Our result suggests 90 and 40 copies/ul of TRECs as the primary and secondary cut-off value.
Conclusion

Detecting the individual TREC contents could be used as the premise to diagnosis the newborns' SCID.
Research on Time Series InSAR Monitoring Method for Multiple Types of Surface Deformation in Mining Area
Authors: Li Yaxing , Yang Keming , Hou Zhixian , Wang Shuang , Ding Xinming , Zhang Jianhong
Published: November 2021

Interferometric Synthetic Aperture Radar (InSAR) has become the main choice of remote sensing detection method for monitoring large surface subsidence and deformation caused by underground coal mining. Time Series InSAR (TS-InSAR) has been intensively researched in mining-caused deformation monitoring for its ability to provide surface deformation time series, with Short Baseline Subset InSAR (SBAS-InSAR) and Permanent Scatter InSAR (PS-InSAR) being two classical methods. To obtain the incline and curvature in mining areas and assess the building damage, this paper exploits the results from SBAS-InSAR and PS-InSAR methods for the estimation of surface incline and curvature, following the principle of directional derivatives, and the surface beneath the villages and the industrial square near the 7221 Grout-filled working face, in the Huaibei mining area of Anhui Province, China, was analyzed. The estimated surface incline and curvature with SBAS-InSAR were within the threshold values specified for Class I damage, while PS-InSAR showed less than 1% measurements which exceeded this threshold. This paper provides a method for monitoring the surface deformation beneath the buildings around the mine area. Meanwhile, the dynamic analysis of the damage degree of buildings provides a basis for the determination of the influence range with grout-filled working faces.
Characterization of 58 STRs and 94 SNPs with the ForenSeq™ DNA Signature Prep Kit in Mexican-Mestizos from the Monterrey City (Northeast, Mexico)
Authors: Aguilar-Velázquez José Alonso , Duran-Salazar Miguel Ángel , Córdoba-Mercado Miranda Fabiola , Coronado-Avila Carolina Elena , Salas-Salas Orlando , Martinez-Cortés Gabriela , Casals Ferrán , Calafell Francesc , Ramos-González Benito , Rangel-Villalobos Héctor
Published: November 2021

Background. STR allele frequency databases from populations are necessary to take full advantage of the increased power of discrimination offered by massive parallel sequencing (MPS) platforms.Material and methods. For this reason, we sequenced 58 STRs (aSTRs, X-STRs, and Y-STRs) and 94 identity informative SNPs (iiSNPs) on 105 Mestizo (admixed) individuals from Monterrey City (Northeast, Mexico), with the Primer Set-A of the ForenSeqTM DNA Signature Prep Kit. Results. Most of the STR markers were in Hardy Weinberg equilibrium, with a few exceptions. We found 346 different length-based alleles for these 58 STRs; nevertheless, they became 528 alleles when the sequence was assessed. The combined power of discrimination from autosomal STRs (aSTRs) was –virtually– 100 % in both length and sequence-based alleles, while the power of exclusion were 99.9999999976065 and 99.9999999999494%, respectively. Haplotypes based on X-STRs and Y-STRs showed 100% of discriminatory capacity. Conclusion. These results provide –for the first time– forensic genomic population data from Mexico necessary for interpretation in kinship and criminal analyses.
Strafrechtlicher Schutz des E-Mail-Verkehrs post mortem?
Authors: Biaggini Elena
Published: November 2021

Der Umgang mit dem digitalen Nachlass ist eine Frage von zunehmender juristischer Bedeutung. Hat der Erblasser keine Vorkehrungen getroffen, so stellt sich aus strafrechtlicher Sicht etwa die Frage, ob sich E-Mail-Provider bei der Herausgabe von Zugangsdaten zu den E-Mail-Accounts des Erblassers strafbar machen. Eine Analyse einschlägiger Strafbestimmungen zeigt, dass eine allfällige Strafbarkeit der Provider grundlegend von der Erbenstellung determiniert wird und eine Strafbarkeit bei der Herausgabe von Zugangsdaten an Erben ausser Betracht fällt.

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L'administration de la succession numérique est une question juridique qui revêt une importance croissante. L'une des interrogations qui se pose est de savoir si les fournisseurs de comptes de messagerie E-mail sont passibles de poursuites pénales lorsqu'ils remettent les données d'accès des comptes du défunt, alors que ce dernier n'avait pris aucune disposition à ce sujet. Une analyse des dispositions pénales pertinentes montre que l'éventuelle responsabilité des fournisseurs est fondamentalement déterminée par le statut des héritiers et qu'elle est exclue lorsque les données d'accès sont remises à ces derniers.
Applying the augmented reality concept in maritime engineering personnel training
Authors: Ivaylo Bakalov
Published: November 2021

The article contributes to a common challenge for linking the academic training with the practical skills of maritime personnel in the current highly dynamic maritime environment. The article presents the concept of augmented reality, wider used in the field of information technologies, applied on the training and exercise of qualified engineering maritime personnel by combining real life data (technical indicators of different aggregates from the ship power system, location and development of fire, flood water, etc.) with computer generated data from the simulation complexes. The elaborated innovative shipboard training procedure of combining the work with the Ship Power Plant simulator, fire accident in the engine room, forecasting and alignment / reconciliation of the scenarios for the development of the fire and counter-action on a real fire field has no analogue.
Talk like a sailor or how to become familiar with the nautical terms and cruise specific lingo
Authors: Camelia Alibec
Published: November 2021

Whenever you travel to a foreign country, it is always a very good idea to pick up the local language. The same technique applies when you go on a cruise; you would like to talk like a sailor, wouldn’t you? Going on a cruise can be compared with visiting a foreign country. Even if English is the language spoken on board a cruise ship, people sound like speaking a cruise-like language which can be defined as a mixture of nautical terms and cruise-specific lingo. Therefore, the cruise ship vocabulary can as well be considered a foreign language to uninitiated travellers. The best think one can do is to have a minimum of information regarding the ship lingo, learn about different aspects of cruise ships and cruise travel, and thus avoid sounding like a landlubber. In addition to all these, if one would like to become fluent in cruise speak, a phrase book is the basic which enables everyone to speak with the crew members and feel surrounded by a friendly environment on their first sailing experience.
The Role of the ESP Teacher
Authors: C. Astratinei
Published: November 2021

The present paper will first of all focus on the literature which approaches issues such as the difference between a General English teacher and an ESP teacher, ESP materials, syllabus, course design and evaluation. Then, emphasis will be placed on the importance of a fruitful collaboration between the ESP and the specialist subject teachers. Next, there will be provided an example of the cooperation between the Maritime English teacher and the Seamanship fundamentals one in point of needs analysis, syllabus and course design. Mention will also be made as to the kind of specialist subject knowledge the ESP teacher is required to avail. Finally, we will conclude our paper with own opinion on the role of the ESP teacher.
Perioperative management of patients receiving long-term antithrombotic therapy. Clinical practice recommendations of the national “Federation of Anesthesiologists and Reanimatologists”
Authors: Zabolotskikh Igor B. , Kirov M. Yu. , Afonchikov V. S. , Bulanov A. Yu. , Grigoryev E. V. , Grigoryev S. V. , Gritsan A. I. , Zamyatin M. N. , Kurapeev I. S. , Lebedinskii K. M. , Lomivorotov V. V. , Lubnin A. Yu. , Ovechkin A. M. , Potievskaya V. I. , Roitman E. V. , Sinkov S. V. , Subbotin V. V. , Shadrin R. V. , Shulutko E. M.
Published: November 2021

The review presents the methodological recommendations of the Federation of Anesthesiologists and Resuscitators for the management of patients receiving long-term antithrombotic therapy, revised in 2021. The classification of complications and the degree of hemorrhagic risk, stratification of perioperative thromboembolic risk are presented. Taking into account modern concepts, the principles of interruption and resumption of antithrombotic, anticoagulant and antiplatelet therapy are described. Approaches to the emergency interruption of antithrombotic therapy during urgent surgical interventions, including emergency reversion of the effects of drugs received by the patient, are presented. The features of the appointment and changes in the tactics of antithrombotic therapy depending on the thromboembolic and hemorrhagic risk in such concomitant diseases and conditions as the presence of artificial heart valves, atrial fibrillation, ischemic stroke, myocardial infarction, coronary stenting are described. A separate section is devoted to thrombohemorrhagic safety when performing regional anesthesia against the background of antithrombotic therapy. Indications, contraindications and limitations for regional anesthesia in the context of antithrombotic therapy are given. Criteria for the quality of the provided medical care are given.
Inhalation therapy with nitric oxide synthesized from atmospheric air in the postoperative period of cardiac surgery in children: single-center retrospective cohort study
Authors: Bautin Andrei E. , Selemir V. D. , Nurgalieva A. I. , Morozov K. A. , Nikiforov V. G. , Biktasheva L. Z. , Afanasyeva K. Yu. , Marichev A. O. , Tashkhanov D. M. , Karpova L. I. , Ivanov I. Yu. , Akhimov P. S. , Buranov S. N. , Karelin V. I. , Shirshin A. S. , Valueva Yu. V. , Domnin S. E. , Pichugin V. V.
Published: November 2021

Objectives. To study the clinical efficacy and safety of using the method of synthesis of nitric oxide (NO) from atmospheric air in the postoperative period of cardiac surgery in children with precapillary pulmonary hypertension (PH). Materials and methods. A clinical study with retrospective control included 90 patients (28 newborns and 62 children older than 28 days), including 40 boys and 50 girls, median age 0.25 (0.28; 1.17) years. The following inclusion criteria were determined: signed informed consent of the patientʼs legal representative, underwent heart surgery, mechanical controlled ventilation (MCV), pulmonary artery systolic pressure (PAPsys) ≥ 35 mm Hg. Exclusion criteria: methemoglobinemia, left ventricular failure III — IV, hemorrhagic diathesis. 45 children were included in the study group (inhalation of NO obtained by synthesis from atmospheric air using the AIT-NO-01 device), 45 children were included in the retrospective control group (application of the NO delivery method from cylinders, NOXBOX Mobile device (Bedfont, UK)). There were no differences in anthropometric parameters and severity of baseline precapillary PH between the groups. Results. After one hour of NO inhalation using the AIT-NO-01, a decrease in PAPsys was noted. by 33.3 % (p < 0.001). In the retrospective control group, after one hour of NO inhalation, there was a decrease in PAPsys by 26.7 % (p < 0.001). PAPsys decreased by 10 % or more in 40 (89 %) of patients in the study group and in 38 (84 %) of patients in the retrospective control group, (p = 0.4). Inhalation of NO obtained by the synthesis method from atmospheric air was associated with a shorter duration of MCV compared with the method of supply from cylinders: 12 (2; 28) h versus 14 (12.2; 70.5) h, p = 0.01. The length of ICU stay and postoperative complications rate did not differ in the study groups. There were no differences in the risk and severity of the side effects of NO inhalation therapy (the synthesis of methemoglobin and NO2) between the two methods studied. Conclusion. NO inhalation therapy after cardiac surgery in children using the AIT-NO-01 device has the same effectiveness and safety compared with the method of NO supply from cylinders.
Morphophysiological responses of table beet irrigated with saline water under application of humic substances
Authors: Sousa Leandra de Melo Cavalcante , Dias Thiago Jardelino , Alves Lunara de Sousa , Véras Mário Leno Martins , Leal Ygor Henrique , Gonçalves Anderson Carlos de Melo , Abrantes Ewerton Gonçalves de , Lopes Adriano Silvano , Lucena Marcos Fabrício Ribeiro , Rodrigues Lucas Soares
Published: November 2021

The use of saline water is an alternative for irrigating agricultural crops, especially in the Brazilian Northeastern semi-arid region, where water quality is limited in most cases. Thus, the objective was to evaluate the morphophysiological responses of table beet cv. “Wonder” irrigated with saline waters under the application of humic substances. The experiment was conducted under a randomized block design, with six replications in a 6 x 4 x 5 factorial scheme, referring to six electrical conductivities of irrigation water (ECw): 0.5; 1.5; 2.5; 3.5; 4.5 and 5.5 dS m-¹, four humic substances rates (HS) (0; 10; 20 and 30 ml per plant), and five stages of assessment (23, 38, 53, 68 and 83 days after emergency). The characteristics evaluated were: plant height, number of leaves, leaf area, chlorophyll content (a, b and total), stomatal conductance, transpiration, net photosynthesis and CO2 internal concentration, and in the soil, the soil pH and the electrical conductivity of saturated paste extract. The increase of salinity reduced growth, chlorophyll a content, and the stomatal conductance of beet plants. The application rate of 30 ml per plant of humic substances promotes an increase in stomatal conductance. The application of humic substances raises the pH in sandy acidic soils. It is recommended to irrigate table beet plants with water of 0.5 dS m-1 associated with the application of 30 mL per plant of humic substances
Antifungal activity and the effect of the essential oil of Lippia origanoides Kunth on Aspergillus mycotoxins production
Authors: Brandão Rafaela Magalhães , Ferreira Vanuzia Rodrigues Fernandes , Batista Luís Roberto , Alves Eduardo , Santiago Wilder Douglas , Barbosa Richard Bispo , Caetano Alex Rodrigues Silva , Nelson David Lee , Cardoso Maria das Graças
Published: November 2021

Lippia origanoides (Verbenaceae) is an aromatic plant of great importance in Brazilian medicine. The antifungal and antimycotoxigenic effects of Lippia origanoides essential oil (LEO) on Aspergillus carbonarius, Aspergillus flavus and Aspergillus ochraceus were investigated. The LEO was obtained by hydrodistillation, and it was characterized by GC-FID and GC-MS. The antifungal activity was determined by mycelial growth and mycotoxin and ergosterol assays. Scanning electron microscopy was used to evaluate the effect of the LEO on the plasma membrane of fungi. The main constituents in the LEO were carvacrol (58.72%), ρ-cymene (15.37%) and γ-terpinene (12.73%). Significant fungicidal effects of LEO against A. carbonarius (0.24 μL/mL), A. flavus (0.98 μL/mL) and A. ochraceus (0.98 μL/mL) were observed. A reduction in the ochratoxin A synthesis that ranged from 92.03 to 98.02% and from 81.72 to 96.92% for the fungal species A. carbonarius and A. ochraceus, respectively, was observed in the presence of LEO. The production of aflatoxin B1 and B2 was qualitatively inhibited. The biosynthesis of ergosterol was significantly inhibited by the application of LEO, and morphological alterations and damage to the integrity of the fungal cell membrane were observed. The LEO has a high potential for use as an antifungal and antimycotoxigenic agent against A. carbonarius, A. flavus and A. ochraceus
Processing of fermented milk drink with different whey concentrations and addition of fruit pulps
Authors: Paula Nélio Ranieli Ferreira de , Araújo Érica de Oliveira , Martins Cristiane Reis , Martins Vanessa Reis
Published: November 2021

Using whey as a complement in food formulation aiming at its utilization is an alternative to obtain new products. The present study aimed to develop a fermented milk drink with different concentrations of whey and addition of cupuaçu, soursop and açaí pulps, aiming at innovating and increasing the possibilities of production and consumption of dairy beverages. The experiment was conducted at the Food Agroindustry of the Federal Institute of Education, Science and Technology of Rondonia, Colorado do Oeste Campus, in the municipality of Colorado do Oeste, RO, Brazil. The experimental design used was completely randomized, in a 3x3 factorial scheme, consisting of three concentrations of whey (30%, 40% and 50%) and the incorporation of three fruit pulps (cupuaçu (Theobroma grandiflorum), soursop (Annona muricata) and açaí (Euterpe oleracea)), with 4 replicates. The results allowed us to conclude that whey concentration of 50% with addition of cupuaçu, soursop and açaí pulps is ideal for the production of fermented milk drink, as it leads to increased acidity and reduced values of °Brix and color parameters L and b*, making it possible to avoid the disposal of a highly nutritious compound into the environment. Whey concentration of 30% in the presence of açaí pulp enables the processing of milk drink with lower value of acidity and higher values of °Brix and color parameters L and b*. Whey concentrations of 30% and 40% in the fermented milk drinks of cupuaçu, soursop and açaí reduced acidity and increased °Brix, which suggests the possibility of using this by-product in the food industry to prepare sweeter milk drinks, meeting the minimum quality requirements according to the current legislation. The processing of whey-based dairy drinks in the presence of pulps of fruits, such as cupuaçu, soursop and açaí, constitutes an opportunity for diversification of production, improvement in the development of regional products and guarantee of food and nutritional security, respecting microbiological quality standards.
Evaluation 16 elite sugarcane lines for ethanol yield and yield related traits under rainfed conditions
Authors: Bunphan Darika , Wanna Ruchuon , Malambane Goitseone
Published: November 2021

The world demand for clean renewable energy has seen a rise in use of sugarcane in production of bioenergy products like bio-ethanol which is produced from molasses and extracted juice of stalk. This then brings a competition between production for food and for bioenergy in the sugarcane industry. Therefore, this calls for breeders and producers to develop and produce high yielding sugarcane varieties to meet the demand. We undertook a study with the aim to screen the recently released elite lines for the ethanol yield and related traits. The study was conducted in two locations under rainfed conditions in Maha Sarakham, Thailand. The results showed that all the locations had no effect on the studied genotypes thus suggesting that they are stable over different locations. The mean values show that SG. KK07-478 and RT2004-085 showed better performance recording higher juice yield, juice weight, TSS, percent of ethanol and estimated ethanol yield in both locations. We found interaction between location and variety except in TSS and percent of ethanol, RT2004-085 showed the highest TSS, juice weight, SG, PE and EEY in combine both locations. A high correlation of EEY to juice yield (0.967***) and juice weight (0.978***) also percent ethanol was highly correlated with TSS (0.953**) this then suggest that to improve ethanol yield breeders should focus on improved the performance of juice yield, juice weight and the TSS. Because of the higher performance, KK07-478 and RT2004-085 should further be evaluated in several other locations before they are adopted by farmers
Estimating maturity by measuring pH, sugar, dry matter, water and vitamin C content of cashew apple (Anacardium occidentale) from remote spectral reflectance data using neural network
Authors: Assoi Eliane K. , Bagui Olivier K. , Kouakou Benoit K. , Gbogbo Adolphe Y. , Soro Doudjo , Zoueu Jeremie T.
Published: November 2021

In agricultural sector, maturity is the main decision criterion for starting the harvest. This criterion is usually revealed by a number of parameters such as pH, sugar, dry matter, water and vitamin C, which are informative but technically tedious to measure. The cashew apple is the hypertrophied peduncle which is attached to the cashew nut. It is a nutritious (very juicy fruit (85 to 90% water), sweet (7 to 13% carbohydrates), acidic and vitamin C content) fruit with high therapeutic and medicinal properties. The cashew apple is used as a raw material for many industrial applications (juice and alcohol). This research was conducted as a preliminary step towards the development of a real-time remote sensing technique for assessing the quality of tropical fruits. Spectral acquisitions were carried out from intact cashew apple using optical system composed reflector coupled with spectrometer USB 4000 FL from Ocean Optics (350-1100 nm). Immediately after spectral acquisition, the samples were analyzed by using chemical methods (sugar content, dry matter content, water content, vitamin C and pH). Preprocessing treatment method, bootstrap method was required to create statistical new samples and to increase the number of samples required. This method was used to improve the predictive performance of calibration model. Statistical models of prediction were developed using an artificial neural network (ANN) method. The results obtained from the models built by ANN showed strong relationships between predicted and experimental values: (Rsquare = 0.9870, RMSE= 0.0262) for pH, (Rsquare=0.9869, RMSE=0.1392) for Sugar, (Rsquare=0.9726, RMSE=0.3333) for water content, (Rsquare=0.9703, RMSE=0.3464) for vitamin C and (Rsquare=0.9922, RMSE= 5.0304, RMSE=5.0304) for dry matter. These results confirm the potential of visible spectroscopy to predict quality parameters of cashew apples remotely and make decisions about best harvest time
Chemotypes of turmeric (Curcuma longa L.) essential oil from four different states of Brazil
Authors: Quemel Franciele da Silva , Dantas Andira Pricila , Sanches Lincon , Viana Ana Cláudia Graças Alves , Silva Eloísa Schneider , Monteiro Eliane Rodrigues , Gazim Zilda Cristiani , Gonçalves José Eduardo , Lopes Ana Daniela
Published: November 2021

Turmeric or curcuma (Curcuma longa L.) is a Zingiberaceae whose essential oil and coloring pigments obtained from the rhizome have been widely used in the food industry and medicine. This study aimed to extract and identify the chemical compounds found in C. longa essential oil from rhizomes collected in six different locations of Brazil. The oil extraction was carried out by hydrodistillation technique, using a Clevenger- type apparatus. The chemical constituents were identified by Gas Chromatography coupled to Mass Spectrometry (GC-MS). The principal component analysis (PCA) and the hierarchical cluster analysis (cluster)were done for the obtained data; and the composition of the studied accesses was verified. Three groups of chemotypes were obtained: group I was formed by the accesses of Campo Grande / Indígena-MS, Mara Rosa-GO, Campo Grande-MS and Perobal-PR, and had Ar-turmerone as its main compound; group II, formed by the access of Santa Tereza do Oeste-PR, presented α-costol and α-Phellandrene as the predominant compounds; and group III, the access of Holambra-SP, differed from the others regarding its essential oil chemical composition whose main agents were Curlone, Zingiberene, β-sesquiphellandrene, Humulene epoxide II, cis-α-trans-Bergamotol. The predominant chemical class in all accesses was hydrocarbon sesquiterpenes (Santa Tereza do Oeste-PR and Holambra-SP) and oxygenated sesquiterpenes (the others). This study evidenced the formation of three chemotypes
The efficiency of Brazilian oat cultivars in reducing fungicide use for greater environmental quality and food safety
Authors: Dornelles Eldair Fabrício , Silva José Antonio Gonzalez da , Colet Christiane  de Fátima , Fraga Denize da Rosa , Pansera Vanessa , Alessi Odenis , Carvalho Ivan Ricardo , Lautenchleger Francine , Rosa Juliana Aozane da , Warmbier Eduarda , Jung Márcia Sostmeyer , Polanczyk Amanda Klidzio
Published: November 2021

Oat cultivars more efficient at reducing fungicide can prevent contamination of soil, water and food. The objective of the study is to measure the efficiency of oat cultivars recommended for growing in Brazil by reducing the number of fungicide applications, considering favorable and unfavorable crop season conditions for productivity and progress of the main leaf diseases. The study was conducted in 2015, 2016 and 2017, in Augusto Pestana, RS, Brazil. The experimental design was a randomized block with three replications in a 22 x 4 factorial scheme, for 22 oat cultivars and 4 conditions of fungicide use [without application; an application at 60 days after emergence; two applications at 60 and 75 days after emergence; and three applications at 60, 75 and 90 days after emergence]. The fungicide FOLICUR® CE was used in 2015 and 2016 and the fungicide PRIMO® in 2017 in the dosage of 0.75 and 0.3 liters ha-1, respectively. The plots were sprayed using BD 04 fan nozzle with 45 PSI pressure, and spray volume close to 120 liters ha-1. The condition of a crop season favorable to the progress of leaf diseases identifies with quality cultivars more efficient in reducing the use of fungicide, enabling processes with lower environmental impacts with food security. Under favorable agricultural year conditions and unfavorable to the productivity and progress of the main leaf diseases of oats, the most efficient cultivars to reduce the use of fungicide are URS Altiva and URS Guria
TÜRK BORÇLAR KANUNU’NDA DÜZENLENMİŞ OLAN “EVDE HİZMET SÖZLEŞMESİ (TBK m. 461-469)” VE TEKNOLOJİK GELİŞMELER IŞIĞINDA EVDE HİZMET SÖZLEŞMESİNİN FAYDALARI İLE UZAKTAN ÇALIŞMA MODELİ VE ESNEK ÇALIŞMA ÜZERİNE DEĞERLENDİRMELER
Authors: GÜLLÜOĞLU ALTUN Yasemin
Published: November 2021

Türk Borçlar Kanunu ile getirilmiş yeni sözleşme türlerinden bir tanesidir. İşçi ve işveren arasında kurulmuş bir sözleşme türüdür. Bu sözleşme gereğince işçi işi kendisinin belirlediği yerde tamamlayarak teslim etmektedir. Evde Hizmet Sözleşmesi belirli veya belirli olmayan bir süre için düzenlenebilir. Bununla beraber aralıklı veya aralıksız çalışma olarak da mevzuatta düzenlenmiştir. Bu sözleşme gereğince tarafların belirlediği ücret üzerinden bir ücret ödemesi de yapılmaktadır. Kendine özgü hükümleri olan bir sözleşme türü olması sebebiyle İş Kanunu’nda düzenlenmiş olan iş sözleşmesi hükümlerinden bazı yönleri ile farklıdır. Evde Hizmet Sözleşmesi özel bir düzenleme olarak kabul edilmektedir. Bu sebeple bu sözleşmenin hükümleri arasında cevap bulunamayan haller söz konusu olduğu zaman başvurulması gereken yasal düzenleme “genel hizmet sözleşmesi” olmaktadır. Evde Hizmet Sözleşmesi atipik bir sözleşmedir. Uygulamada bu sözleşmenin işçi tarafının en fazla kadınlar olduğunu görmekteyiz. Zira bu sözleşme uzaktan çalışmayı içinde barındırdığı için kadınlar tarafından tercih edilmektedir. O halde gelişen teknolojilere ayak uydurulması açısından mevcut yasal düzenlemelerin geliştirilmesi gerekmektedir.
Asisten Navigasi untuk Orang dengan Gangguan Penglihatan Menggunakan Ultra Sonic (Sonar Vision) Untuk Yayasan Mitra Netra
Authors: Susanto Rudi
Published: November 2021

Generally, people with visual impairments in the low vision category use sticks to find ways to deal with obstacles in front of them. However, this detection can only be felt as long as the stick is used. The purpose of this community service activity is to made a sonar vision set using a sonar sensor that can be attached to the wrist and belt. This device is designed to detect obstacles up to a distance of 3 meters. This activity was carried out at the Mitra Netra Foundation. The approach used is the creation, provision and education of the use of the Sonar Vision module for people with visual impairments. The results of this activity show that 100 low vision sufferers have benefited from this system, where 84% of them feel that sonar vision helps them in navigation.
Business Opportunities in Industrial Revolution 4.0 through 9 (nine) E-commerce Marketing Strategies
Authors: Sardjono Wahyu , Nuriana Winda Dian
Published: November 2021

Technological developments in industry 4.0 which lead to digital technology create new ideas for companies to take strategic steps in business processes. One of them is utilizing electronic commerce. This study uses a qualitative analysis approach which uses secondary data. The methodology used is conceptual review by gathering data and information that are interrelated. The information collected is market opportunity, consumer behavior and electronic commerce technology as an innovation in marketing. This research is expected to create potential market opportunities. The marketing strategy used is the strategy of utilizing technology, market opportunities, marketing strategies, designing consumer knowledge, creating consumer interfaces, increasing customer information creating marketing programs, and evaluating marketing programs using technology and information and program evaluation.
Reconstruction of the Old Castle of Hrodna
Authors:   European Humanities University, Volkau Mikola Aljaksandravich
Published: November 2021

The Old Castle in Hrodna is the most important architectural monument for Belarus in terms of its historical value, since it is the only architectural object in the country where state institutions have functioned for more than seven centuries. Active reconstruction of the castle, which began in 2016, showed that the «revival» of this building is supported by a significant part of the Belarusian society and elites, also due to the fact that castles are perceived as important symbols in the Belarusian national narrative. At the same time, such heritage objects are quite convenient in terms of interpretation and, depending on the situation and needs, can be used as symbols of different ideas and concepts. The reconstruction of the Old Castle is the quintessence of the «romantic» approach to the restoration of architectural monuments, when the basis of the concept is the desire to restore the object for a certain narrow period «in all its greatness». The project for the reconstruction of this castle is characterized by the desire to increase the architectural volumes in height in order to create a more expressive image. At the same time, the works performed in 2017–2020 showed that a significant part of architects, officials and the Belarusian society are not embarrassed by the striking difference between the proposed image and how the castle looked according to historical sources. However, the implementation of this approach threatens the Old Castle with a loss of authenticity, which is the greatest value of this monument in the long term.
The culture of the Slavic and Balkan countries in reports of participants of the International scientific conference «Art and culture of the Middle Ages. Heritage and perspectives for comprehension»
Authors:   St. Petersburg State University, Maltseva Svetlana Vladislavovna , Staniukovich-Denisova Ekaterina Iurievna ,   St. Petersburg State University
Published: November 2021

The article deals with the course and results of the International scientific conference «Art and Culture of the Middle Ages: Heritage and Perspectives of Comprehension» (https://actual-art.spbu.ru/o-konferentsii/arkhiv/2020/iskusstvo-i-kul-tura-srednevekov-ya.html), as part of the international symposium «Actual Problems of Theory and History of Art», held by St. Petersburg State University together with Lomonosov Moscow State University and the leading museums of Russia in the mode of the Biennale. The event was organized with the support of the Russian Foundation for Basic Research (project No. 20-012-22040) and took place in St. Petersburg on October 26–31, 2020.
Methodology for Assessing the Risks of Information Enterprise Security Using Case Technologies
Authors: Gavrilov А. V. , Sizov V. A. , Yaroshenko E. V.
Published: November 2021

Purpose of the study. Creating an effective information security system of an enterprise is impossible without an adequate assessment of the risks to which its assets are exposed. The results of such an assessment should become the basis for making decisions in the field of information security of the enterprise. Identification of information assets and assessment of their value, determination of the level of threats to the security of assets allow planning measures to create an enterprise information security system.This paper discusses a methodology for assessing the risks of information security of an enterprise, a distinctive feature and novelty of which is the use of modern tools and methods for constructing and analyzing business processes in order to identify the information assets of an enterprise to be protected.Materials and methods. It is proposed to identify information assets based on the model of business processes of the enterprise, performed using the IDEF0 methodology. Modeling of business processes was carried out in the Business Studio environment of the “Modern Management Technologies” company.The activity of a typical IT-industry company was considered as an example for the risk analysis.Results. The methodology for assessing the risks of information security of an enterprise described in the article has been successfully tested in the educational process. Its use in conducting laboratory classes in the discipline “Designing the information security system of enterprises and organizations” for masters studying in the direction of “Information security” allowed, according to the authors of the article, to increase the effectiveness of the formation of students’ professional competencies.Conclusion. The paper proposes a methodology for assessing information security risks for objects of an enterprise’s information infrastructure, which makes it possible to identify priority areas of information security at an enterprise. As a result of the application of the technique, a loss matrix is formed, showing the problem areas in the organization of information protection, which should be given priority attention when planning information security measures. Based on the data obtained, it is possible to form an economically justified strategy and tactics for the development of an enterprise information security system.
Analysis of chemical characteristics and antioxidant activity test of kombucha black tea and butterfly pea flower (Clitoria ternatea L.) based on fermentation time
Authors: Sintyadewi Putu Rima , Rabani RS I Gusti Agung Yogi , Wulansari Nadya Treesna
Published: November 2021

Free radicals are one of the triggering factors for degenerative diseases. Free radical activity can be minimized or prevented in the presence of antioxidant compounds. The butterfly pea flower (Clitoria ternatea L.) has long been used as a traditional medicine to cure various diseases. Previous research has shown that the Butterfly pea flower has bioactive compounds, one of which is flavonoids, which act as antioxidants. Butterfly pea flower can be used as another substitute in making black tea-based kombucha drinks. Kombucha fermentation can increase the benefits of Butterfly pea flower with the presence of organic acids, minerals, and vitamins produced during the fermentation process. This study aims to determine the effect of fermentation time on chemical characteristics including pH, reducing sugar content, and antioxidant activity. Based on analysis of variance ANOVA showed that the length of time fermentation had a very significant effect (P>0.01) on pH, reducing sugar content and antioxidant activity of black tea and Butterfly pea flower kombucha. The longer the fermentation time, the lower the pH and sugar content in the medium. Optimum antioxidant activity occurred on the 8th day of fermentation in the variation of treatment P3 (3:3) which was 89.74%. These results indicate that black tea kombucha and Butterfly pea flower are categorized as having high antioxidant activity at the interval of 68.45% to 89.74%.
Axiological approach in professional pedagogical education
Authors: Antoniuk Volodymyr Z. , Alendar Nadiya I. , Bartkiv Oksana S. , Honcharuk Olha V. , Durmanenko Oksana L.
Published: November 2021

This scientific research examines the issues related to the axiological aspect of the professional training of future teachers. The relevance of the stated research topic is determined by the urgent necessity to increase the importance of high-quality professional training of future representatives of pedagogical professions, in the context of changes taking place in the modern education system. The purpose of this research work is to identify and state the main components of the axiological aspect of the professional training of future workers in the pedagogical industry, which is able to impart integrity to the entire process of their training. The leading approach in this scientific study is a combination of quantitative and qualitative methodological approaches to the study of issues related to the axiological aspect of the professional training of future workers in the pedagogical industry, in order to determine the main components of the factors affecting the quality and effectiveness of this training and further professional activities of teachers. The main results of this research work were: a statement of necessity to develop and take a set of measures to clarify the existing value criteria of the education system to future teachers at the stage of their university preparation.
An App-Based Intervention for Adolescents Exposed to Cyberbullying in Norway: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Kaiser Sabine , Martinussen Monica , Adolfsen Frode , Breivik Kyrre , Kyrrestad Henriette
Published: November 2021

BACKGROUND

Adolescents exposed to negative online events are at high risk to develop mental health problems. Little is known about what is effective for treatment in this group. NettOpp is a new mobile app for adolescents who have been exposed to cyberbullying or negative online experiences in Norway.

OBJECTIVE

The aim of this paper is to provide a description of the content of the intervention and about a randomized controlled trial that will be conducted to examine the effectiveness of NettOpp. This protocol is written in accordance with the Spirit 2013 Checklist.

METHODS

An effectiveness study with a follow-up examination after 3 months will be conducted to evaluate the mobile app. Adolescents will be recruited through schools and will be randomly assigned to the intervention (NettOpp) group and a waiting-list control group. The adolescents (aged 11 to 16 years) will respond to self-report questionnaires on the internet. Primary outcomes will be changes in mental health assessed with the Strengths and Difficulties Questionnaire, the WHO-Five Well-being Index, and the Child and Adolescent Trauma Screen.

RESULTS

Recruitment will start in January 2022. The results from this study will be available in 2023.

CONCLUSIONS

There are few published evaluation studies on app-based interventions. This project and its publications will contribute new knowledge to the field.

CLINICALTRIAL

ClinicalTrials.gov NCT04176666; https://clinicaltrials.gov/ct2/show/NCT04176666

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/31789