bluuebunny/crossref_metadata_2025 huggingface dataset:
Odnosi z notranjo javnostjo in interna komunikacija kot pogoj uspešnosti podjetja
Authors:   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Lenardič Jera , Novak Vesna ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Đorđeski Marina ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

Communication is what enables our being to articulate our feelings, thoughts and transmit our knowledge. The choice of words, our facial expressions and body gestures, and the observance of the rules depend on the place and the public with whom we establish contact. We learn communication skills and thus gain (self)value, which is related to our performance, both in private and professional life. The paper focuses on internal communication, which interdependently influences not only the establishment of better relationships within and between different publics in the company, but also the one that establishes a more creative work environment. Communication approaches are those that enable the performance of work tasks in a faster and more efficient way and further raise the level of productivity. It is clear that it is very important who, to whom, through which channel, and for what purpose, communicates something, as internal communication is the main obstacle to the (non)success of the particular company.
Kognitiven pristop k motivaciji in učenju pri višješolskih študentih
Authors:   Biotehnical Centre Naklo, Higher Vocational College, Naklo, Slovenia, Maček Jerala Milena
Published: June 2022

In the article, we focused on the connections between learning or. academic motivation and learning strategies in higher education. In the theoretical part, we explained the basic concepts on the basis of the read literature listed in the bibliography, and in the empirical (research) part, we conducted a survey of students of Higher Vocational College. We used the freely available Questionnaire of Motivation and Learning Strategies, based on a cognitive approach to motivation and learning, which is characterized by emphasizing the intertwining of cognitive and emotional components in learning. There is a statistically significant medium-strong positive association between beliefs about self-efficacy and repetition and elaboration, and a weak positive association with the organization. There is a statistically significant weak positive association between metacognition and time and learning space, peer learning and seeking help - with more frequent use of metacognitive strategies, mastery of time and learning organization strategies, turning to peers or teachers for help increases statistically significantly.
Optimiranje spletnih strani za iskalnike v kontekstu digitalnega marketinga
Authors:   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Arh Patrik , Černivec Žan ,   University of Ljubljana, Faculty of Social Sciences, Ljubljana, Slovenia, Arh Evelin ,   SŠFKZ, Ljubljana, Slovenia, Blažko Kaja ,   Gimnazija Vič, Ljubljana, Slovenia, Marič Miha ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

The field of digital marketing is very topical, as it is part of the strategy of almost every company. Proper use of digital marketing techniques has a positive effect on a company's reputation, online visibility and conversion. Digital marketing includes presence on social networks, presentation with one's website, etc. In doing so, web users must find our website among the search results. This is the field of search engine optimization, as it uses various techniques and approaches to prove to search engine algorithms that our website is worth visiting and the time users spend on it. The goal is to continuously update and change the website to make the content transparent, useful, meaningfully structured and supported by images, videos and other graphic content. It is also necessary to devote a lot of time to other, more technical details, which also have a key impact on the ranking of our website at the top of search results. In the research, we used the method of critical review of secondary sources of literature and used the method of synthesis to form an overview of the considered areas.
Embedding Sustainability into Asset Management: A Case Study
Authors:   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Maletič Damjan , Marques De Almedia Nuno ,   Instituto Superior Tecnico, University of Lisbon, Lisbon, Portugal, Lovrenčić Viktor ,   C&G d.o.o. Ljubljana, Ljubljana, Slovenia, Maletič Matjaž ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

Industrial and manufacturing systems have a major impact on all aspects of sustainability. Asset management is an important factor for companies seeking to improve their sustainability performance. This paper examines the areas in which companies incorporate sustainability aspects into their asset management decisions and activities. It uses two Slovenian companies as an empirical case study. The results show that both companies actively incorporate sustainability into their asset management practice. The weakest inclusion was found in asset management policy, strategy and objectives. Risk management is another area to focus on, as well as activities related to asset information. The stronger involvement of sustainability in asset management activities was related to organization and people. Support from top management was found to be moderate rather than strong. The study's findings underscore the areas where asset managers should focus to boost their contribution toward sustainability
Etika in vrednote študentov
Authors:   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Marinčič Dejan , Marič Miha ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

The paper studies the values and ethics of students. In Slovenia, the value orientations, and views on ethics change with growing up, as in other developed countries. The key changes occurred during the transition from the traditional to the modern, and then to the postmodern information society. Differences in values and views on ethics are perceived through generations. Therefore, we ask a research question, how do students evaluate their values and how high is their self-esteem of ethics. 182 undergraduate students were included in the study. Data collection took place from March 2020 to December 2021. Through the analysis of collected data based on students’ selfassessments, we determine which type of values, and which individual values are best assessed, and how they evaluate their ethics. We conclude the article by giving our opinion based on the findings of the research.
Vodenje v kontekstu Cov-19: izzivi in priložnosti v Sloveniji
Authors:   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Arh Patrik , Černivec Žan ,   University of Ljubljana, Faculty of Social Sciences, Ljubljana, Slovenia, Marič Miha ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

The world we have been living in for the last two years is a world that none of us expected. In a very short time, we have been confronted with the facts that define the new reality. It is different, but in the opinion of many, it is also worse, more limited, dark and sad. The paper aims to comprehensively present various aspects of this situation; determine whether the new coronavirus presents more challenges or opportunities for short-term or long-term success; and focus mainly on the analysis of the leadership of Slovenian companies during Cov-19. In this paper, we used the method of critical review of current sources of literature, and with the method of synthesis, we presented two main topics of the paper, the general presentation of the Cov-19 virus and the leadership of Slovenian companies in crisis situations. To present the connection, impact and consequences of the pandemic at the micro and macro level. The paper encourages critical thinking about whether a pandemic can be a factor in evaluating the work of leaders in their companies to the point of a virus outbreak.
Public - Private Partnership in Health
Authors:   Insitutie for Serbian Culture Priština-Leposavić, Serbia, Arsenijević Olja , Lugonjić Marija ,   University »Union – Nikola Tesla«, Faculty of Business Studies and Law, Belgrade, Serbia, Šprajc Polona ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

The WHO World Health Organization encourages PPP and believes that it is inevitable in healthcare because it represents significant opportunities. The WHO strategy is the promotion and protection of public health, which is presented in this way as well. Achieving the goals and economic launch of the PPP project requires a lot of resources and knowledge. The focus should be on the development of a methodology related to the preparation of a PPP project. PPP - partnership in healthcare is a strategy to increase efficiency. We will present the advantages and disadvantages of public-private partnerships in healthcare in the Republic of Serbia, in the Republic of Croatia, PPPPartnerships of Canada and healthcare in the UK-as well as development, legal regulation and institutional support.
Kompetence uspešnih kadrovskih strokovnjakov
Authors:   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Bergoč Zala , Podbregar Iztok ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia, Đorđeski Marina ,   University of Maribor, Faculty of Organizational Sciences, Kranj, Slovenia
Published: June 2022

Competencies are all characteristics, attributes and knowledge, which are needed to complete a job, or those that people have in general. Only competent personnel can achieve results. A person can be intelligent, but will not be efficent in the work field, if he is not interested in the job. A person could also be a quick learner, however he cannot use the proper knowledge in the workplace, due to his lack skills. Thus an HR expert is only as successful as his skills and interest in the job. This article focuses on competencies of the HR personnel, which are crutial for their field of work. In this article we also present the findings of researches, that suggest what kind of problems are HR specialists facing when seeking employment. We have researched why some candidates are more successful than the others in job hunting and how does today's technology effect HR.
Zespół akt dekanatu szadkowskiego w zasobie Archiwum Diecezjalnego we Włocławku. Część I
Authors: Szkutnik Piotr
Published: June 2022

This contribution presents the documents and records relating to the  Szadek decanate, forming a separate file in the archives stored in the Diocesan Records Office in Włocławek. It first outlines the life and work of the author of these archives, and then describes their form and content. Legal regulations constitute the main part of the records; documents describing the decanate are much less numerous.
Przegląd wybranych stanowisk dotyczących teorii gerotranscendencji
Authors: Muszyński Marcin
Published: June 2022

The purpose of this article is a brief overview of selected positions concerning gerotranscendence theory. The author presents a set of assumptions as well as a set of concepts with statements. Finally, the selected positions which evaluate the theoretical outputs of Lars Tornstam attract the main attention.
​​Clinical, Pathological and Molecular Diagnosis of Peste des Petits Ruminants in Saudi Arabia
Authors: Hamouda M.A. , Al-Hizab F.A. , El-Sabagh I.M.
Published: June 2022

Background: Peste des Petits Ruminants (PPRV) is one of the major notifiable diseases of the world organization for animal health (OIE) and its existence can have a catastrophic. So far, the epidemiological situation of the virus a in Saudi Arabia is not clear. The study was designed to assess the viral infection in indigenous sheep and goats. Methods: A herd was struck by the virus. Clinical signs were recorded and postmortem examination was carried out on dead animals. Tissue samples from oral cavity, abomasum, small and large intestine, spleen and mesenteric lymph nodes as well as lungs were fixed in 10% neutral buffered formalin and processed routinely. Paraffin wax-embedded sections were stained with haematoxylin and eosin. Similarly tissues were also collected and stored at -80°C for PCR test. Result: PPRV was detected by RT-PCR and the fragment size of the amplified products was 191 bp of M gene. The clinical signs were a sudden onset of fever with excessive salivation associated with mucopurulent discharges from the nose and eyes. At necropsy, fibrinonecrotic stomatitis associated with hepatized lung especially in the cranioventral lobes. The large intestine showed streaks of congestion “zebra stripes”. Histologically, lungs showed interstitial pneumonia characterised by thickening of alveolar septa and presence of syncytial cells. Small and large intestine revealed fibrinonecrotic enterocolitis characterized by massive necrosis of mucosa accompanied by mononuclear cell infiltration as well as severe congestion of the submucosal blood vessels.
Molecular Variability of Colletotrichum spp. Associated with Anthracnose of Soybean
Authors: Kavanashree K. , Jahagirdar Shamarao , Priyanka K. , Uday G. , Kambrekar D.N. , Krishnaraj P.U. , Basavaraja G.T. , Patil M.S.
Published: June 2022

Background: Anthracnose is a major foliar disease of soybean associated with Colletotrichum species. In India, C. truncatum is the most widely associated species, whereas, other species are also being reported to cause anthracnose disease in soybean. Methods: Twenty-eight soybean infected samples were collected from different location of India, in order to obtain the pure cultures and were subjected to pathogenicity test. Microscopic observations were made for morphological characterization of all the isolates. Molecular detection was carried out using ITS primers and the sequences were deposited in the NCBI GenBank. Phylogenetic analysis was made using the MegaX bioinformatics tool. Result: The pure cultures were subjected to pathogenicity test, which had reproduced similar symptoms found under field conditions. Microscopic observations on spore morphology were made which revealed that truncate conidia were associated in twenty-seven isolates and cylindrical conidia in one isolate. Molecular detection made showed sequence similarity to Colletotrichum truncatum and the isolate with cylindrical spore was sharing homology with C. plurivorum. Phylogeny analysis clustered the two species into two groups. Hence, the study shows the association of two distinct species in causing anthracnose of soybean.
Educación ciudadana y el uso de estrategias didácticas basadas en TIC para favorecer el desarrollo de competencias en ciudadanía digital en estudiantes
Authors: Contreras Pardo Constanza María José , Vera Sagredo Angelica
Published: June 2022

En una sociedad inserta en la nueva era digital, hoy en día es importante contar con una educación en ciudadanía digital que se oriente al desarrollo de competencias que faciliten aprendizajes y puedan contribuir a la participación democrática, informada y responsable en entornos digitales. El objetivo es analizar cómo el uso de estrategias didácticas basadas en TIC favorece el desarrollo de competencias en ciudadanía digital en estudiantes de enseñanza media. La investigación se abordó desde la perspectiva del paradigma cuantitativo y como un espacio para determinar las preconcepciones en ciudadanía digital y el uso de TIC en 138 estudiantes de enseñanza media. Se implementó una secuencia didáctica con la finalidad de favorecer el desarrollo de competencias digitales en estudiantes, determinando las variables posteriores a su implementación, para lo cual se utilizó el software estadístico SPSS® 21. Los principales resultados dieron cuenta que los estudiantes reconocen a los medios digitales como facilitadores en el acceso a la información de manera efectiva, la participación que puede lograr la ciudadanía en movimientos ciudadanos gracias a los entornos digitales, los peligros presentes en la comunidad digital, la participación ciudadana en demandas sociales de interés, además de entregar información relevante para la sociedad a través del uso de las TIC. En base a los objetivos de la investigación es posible concluir que las estrategias didácticas basadas en TIC, utilizadas en la secuencia didáctica, favorecieron el desarrollo de competencias en ciudadanía digital en estudiantes; se refuerza la anterior idea, producto de que las actividades de aprendizaje realizadas permitieron el acceso a información, investigación, comunicación, presentación e intercambio de información y, por sobre todo, la participación en temáticas de interés ciudadano como uno de los objetivos principales.
Self-regulation and Learning Strategies of Beginner and Advanced University Students
Authors: Belletti Cecilia , Vaillant Denise
Published: June 2022

The authors analyze the self-regulation learning processes of university students from a degree in the area of computer systems in a private University in Uruguay. An analysis is made of the main features that characterize self-regulation processes drawn from a quant-qual investigation based on a pre-existing questionnaire adapted to this particular context. Such is the Motivated Strategies for Learning Questionnaire (MSLQ), which was administered to 187 students; semi-structured interviews were also carried out to 10 students. Among the most important results of the study, it is worth emphasizing the high level of intrinsic and extrinsic motivation and the diversity in the self-regulation learning strategies used by beginner and advanced students. Concerning the cognitive strategies, students mainly use deep information-processing strategies. Some of the self-regulation processes are developed in keeping with the beginner and advanced students' academic progress.
El abandono escolar en educación media superior: afiliación institucional y dinámica familiar en estudiantes de Sonora, México
Authors: López Borbón María Fernanda , Cubillas Rodríguez María José , Román Pérez Rosario , Abril Valdez Elba
Published: June 2022

This investigation examines the relationship between the institutional affiliation of high school students with school dropouts and the family environment. The study was longitudinal, a survey was applied to 1786 firstyear students. The school dropout rate was 17.5%. An analysis that compared the means obtained between those who dropped out and those who remained, in relation to the study dimensions, showed lower self-assessments in the aspects evaluated. The students who remain at school conferred greater importance to higher secondary education, have a greater vision of the future, better academic performance, and study and self-learning skills. The negative perception of their family environment and the presence of physical and verbal violence had a negative effect on the analyzed study dimensions.
Uso de recursos educativos digitales y ambientes virtuales de aprendizaje para la enseñanza de matemáticas en ingeniería. Sistematización de la experiencia docente
Authors: Díaz Montes Luis Alberto , Barrera Zapata Rolando
Published: June 2022

This article details the systematization of the experience related to the didactic use of digital educational resources in the Special Mathematics course of the Chemical Engineering program at the University of Antioquia, aiming to evidence the advantages of the resources implemented in the processes of teaching-learning under normal conditions (before the pandemic). In this context, it was evidenced that the use of virtual platforms to access class information asynchronously, the use of software to illustrate the course topics in a practical way, and the availability of video tutorials are the three resources best valued by students while helping to achieve the training purposes of the course.
Pensar la virtualidad desde la didáctica. Reflexión crítica de los entornos virtuales de educación
Authors: Flórez Arias Nilson Arley
Published: June 2022

ma nitibus, volupient fuga. Osapitas que veliquae con rem incto te quias et omnis evellamusti doluptatusae necte nobis aute ea ius de ommoluptatur aborectur? Qui blaborem faceruntiore velia vendent qui voluptatquam similiqui rehent, et, aut ea soloriat volendam iniminv elestempore, utem nia quaecat ullabo. Nam quide audigent. Quiae am venditius, sequiducium faccaecus consectessum adis eum ad ulpario que repratis magnis estem aribus as mint at occae volorro que volorro et remped et lanihit iatinulpa dolor aut ut atem niscipsus dem quas expe volupicit optum dellupt atisitiatet qui re, officat atemporis endae verrorendis aspero con con poresti ius ne od que conem dolupie ntotatem utaeptatibus sam reris.
Formación de investigadores en contextos digitales
Authors: Chávez Blanca Estela
Published: June 2022

This article is part of the discussion about the relationship between research and training in digital contexts. In this context, the generation of online training proposals led us to investigate the structures of meaning that researchers conceive in training. Thus, through structural analysis, an exploratory, empirical-inductive analysis is presented; a product of the analysis of positive and negative codes manifested in the discourse on an online doctoral program, resulting in the identification of two cultural models: functional academic and the constructive academic, in which two tensions are conceived in training in digital contexts: a regulated-hierarchical one, opposed to the spontaneous-constructive one, and the homogeneous one, opposed to the heterogeneous one.
Identidad social en raperos de Lima
Authors:   , Zavaleta Espinoza Laura Giuliana
Published: June 2022

El objetivo del estudio es analizar los procesos de construcción de la identidad social en raperos de Lima. Participaron 10 personas de sexo masculino cuyas edades fluctuaron entre los 23 a 26 años, quienes reconocen pertenecer a la cultura hip hop desde hace más de seis años. La metodología utilizada fue cualitativa con diseño fenomenológico. La técnica de recolección de información fue la entrevista enfocada. Se utilizó el análisis temático para establecer las siguientes categorías: características del grupo, valor otorgado al grupo y diferencias con otros grupos de rap. Los resultados señalan que estos jóvenes son parte de la cultura hip hop al encontrar elementos que les otorgan satisfacción, brindándoles así una reafirmación y beneficios a su identidad social.
Yalomov interpersonalni model skupinske terapije in njegova aplikacija na akutni psihiatrični enoti
Authors: Škrila Čuš Darja , Kremžar Jovanović Borjana
Published: June 2022

V prispevku je predstavljen Yalomov interpersonalni model skupinske terapije za nižje funkcionirajoče hospitalizirane bolnike ter njegova uporaba na akutnih enotah oddelka za psihiatrijo. Navedeni so objavljeni primeri uporabe tega modela na akutnih psihiatričnih enotah, ki pa so maloštevilni. Podrobneje je predstavljen teoretični okvir bolnišnične skupinske terapije po Yalomu, in sicer klinični dejavniki, specifični za bolnišnično okolje, ter potrebne modifikacije skupinske tehnike. Opisani so cilji bolnišnične skupinske terapije, ki morajo biti predvsem realistični, ter druge značilnosti bolnišnične skupine, kot so sestava in velikost skupine, časovni okvir, pravila zaupnosti idr. V nadaljevanju so navedene strategije in tehnike vodenja bolnišnične terapevtske skupine ter delovni model psihoterapevtske skupine za nižje funkcionirajoče bolnike. V zadnjem delu članka je predstavljena aplikacija tega modela v praksi, in sicer gre za skupino, ki je sestavljena iz bolnikov z moške in bolnic z ženske akutne enote, poteka enkrat tedensko, vodita pa jo klinični psihologinji. V članku je opisana osnovna struktura skupine, cilji terapevtskega procesa, obravnavane vsebine ter evalvacija s strani bolnikov, ki se izvaja v zaključni fazi vsake skupine. Bolniki ocenjujejo skupino kot koristno, naloge, ki se jih lotevajo v skupini, pa se jim zdijo ustrezne.
Depresión psicótica secundaria a hipertiroidismo y desenlace letal por tormenta tirotóxica: a propósito de un caso.
Authors: Orihuela-Carpio Fiorella Stephani , Magno-Muro Priscilla , Cruzado Lizardo
Published: June 2022

El rol de exceso y déficit de hormona tiroidea en la patogenia de trastornos del ánimo se ha registrado desde hace casi dos siglos. Las patologías tiroideas, las más numerosas dentro de las enfermedades endocrinas, se asocian causalmente a patología psiquiátrica en un importante porcentaje de casos. Específicamente, el hipertiroidismo produce múltiples manifestaciones psicopatológicas de tipo ansioso y depresivo, episodios de manía e, infrecuentemente, psicosis. Aunque el influjo del eje tiroideo sobre las vías neurales de noradrenalina, dopamina, y serotonina juega un rol neurobiológico fundamental en estos fenómenos, existen todavía múltiples mecanismos subyacentes por dilucidar. Dada la necesidad de un diagnóstico diferencial amplio y abarcador entre patologías psiquiátricas primarias y secundarias, reportamos el caso de una paciente de 52 años con depresión psicótica, en la que el diagnóstico tardío de hipertiroidismo acarreó consecuencias penosas y letales. La valoración clínica y laboratorial de la función tiroidea, debe ser parte de la evaluación psiquiátrica de cualquier persona con trastornos afectivos y ansiosos.
TASARIM DÜŞÜNCESİ BİLEŞENLERİ VE İÇ MİMARLIK EĞİTİMİ ÇERÇEVESİNDE DEĞERLENDİRİLMESİ
Authors: KURT CAVUŞ Özlem , KAPTAN B. Burak
Published: June 2022

Tasarım düşüncesi, “yaratıcı sorun çözme süreci” olarak tanımlanmaktadır. Bu kavram, son yıllarda

kullanımı birden fazla alanda yaygınlaşmakta olan değer, ilke ve yöntemleri kapsayan yaratıcı sorun çözme

aşamalarını barındırmaktadır. Yaratıcı sorun çözme süreci temeline dayalı tasarım alanlarından biri olan

iç mimarlık eğitimi içeriğinde, tasarım düşüncesi ilkeleriyle sıklıkla karşılaşılmaktadır. “Tasarım düşüncesi

bileşenleri”, bu çalışma kapsamında tasarım düşüncesinin sorun çözme yaklaşımı olarak uygulanmasında,

birey için gerekli olan tutum, ilke, değer, bakış açısı gibi özellikleri anlatmak için kullanılabilecek en kapsayıcı

ifade olarak belirlenmiştir. Bu bileşenler, bireylerin tasarım düşüncesini kullanarak yaratıcı sorun çözmeye

dönük zihin yapısını ifade etmektedir. Bu çalışma kapsamında, tasarım düşüncesi kavramını oluşturan temel

bileşenlerin, alanyazın incelemelerinden elde edilen nitel verilerin sınıflandırılması yoluyla belirlenmesi

hedeflenmiştir. Sonuç olarak, tasarım düşüncesi alanyazınında ulaşılabilen ve nitelikli kaynakların doküman

analizi ile değerlendirilmesine göre, bu kaynaklardan çıkarılan tasarım düşüncesi bileşenleri bir araya

getirilmiş ve iç mimarlık eğitimi içeriğine yönelik uluslararası düzeyde geçerliliği olan iç mimarlık mesleki

yeterlilikleri ile tasarım düşüncesi bileşenleri arasındaki ortak değerler ortaya konularak tartışılmıştır.
REZERVE BOYA VE BASKI TEKNİKLERİ İLE ÜRETİLEN İNDİGO BOYALI AFRİKA TEKSTİLLERİ
Authors: TATLIDİL Ülker , ÖĞÜT Leyla
Published: June 2022

Mavi renk veren doğal kaynaklar tarih boyunca çeşitli topluluklar tarafından tekstillerin

renklendirmesinde kullanılmıştır. Sentetik boyar maddelerin gelişmesi ve yaygınlaşmasından önce Afrika

toplulukları da tekstilleri maviye boyamak amacıyla farklı indigo kaynaklarına başvurmuşlardır. Bu çalışmada

doğal indigo boyanın kaynağına bakılmaksızın rezerve tekniği ile mavi renge boyanmış Afrika tekstilleri

incelenmiş ve bu tekstillerin hangi rezerve teknikleriyle, hangi bölgelerde üretildikleri ortaya konulmaya

çalışılmıştır. Çalışmada Afrika’da üretilen indigo boyalı rezerve tekstillerin ayrıntılı bir sunumu ve sınıflandırması

yapılarak alanyazında bu konudaki eksikliklerin giderilmesi amaçlanmıştır.

İndigo boyalar ile renklendirilen tekstillerin çoğunda rezerve boyama tekniklerinin kullanıldığı görülmektedir.

Bunlar fiziksel rezerveden kimyasal rezerveye kadar çeşitli şekillerde farklı topluluklarda uygulanmaktadır.

Elde edilen bulgulara göre; rezerve tekniği Afrika’da yaygın olarak görülen geleneksel bir tekstil boyama

tekniğidir ancak indigo ile rezerve boyama tekniği yoğun olarak Batı Afrika ülkelerinde uygulanmaktadır.

Ulaşılan kaynaklarda Batı Afrika haricinde rezerve tekniği ile indigo boyama yapıldığına dair veriler bulunsa

da bu uygulamaların geleneksel uygulamalar değil daha çok turizm amacıyla, sentetik boyalarla gerçekleştirilen

üretimler olduğu, tekstillerde genellikle üç çeşit indigo kaynağının kullanıldığı ve bazen asıl tekniği gizlemek

amacıyla farklı rezerve tekniklerinin görünüşünün taklit edildiği bilgilerine rastlanmıştır. Bu bağlamda Afrika’da

zengin çeşitliliğe sahip indigo rezerve boyamaların tekniklerini tespit etmenin hem teorik hem de uygulamalı

çalışmayı gerektirdiğini ifade etmek mümkün olmaktadır.
Exosome secretion from hypoxic cancer cells reshapes the tumor microenvironment and mediates drug resistance
Authors: To Kenneth K. W. , Cho William C. S.
Published: June 2022

Hypoxia is a common phenomenon in solid tumors as the poorly organized tumor vasculature cannot fulfill the increasing oxygen demand of rapidly expanding tumors. Under hypoxia, tumor cells reshape their microenvironment to sustain survival, promote metastasis, and develop resistance to therapy. Exosomes are extracellular vesicles secreted by most eukaryotic cells, including tumor cells. They are enriched with a selective collection of nucleic acids and proteins from the originating cells to mediate cell-to-cell communication. Accumulating evidence suggests that exosomes derived from tumor cells play critical roles in modulating the tumor microenvironment (TME). Hypoxia is known to stimulate the secretion of exosomes from tumor cells, thereby promoting intercellular communication of hypoxic tumors with the surrounding stromal tissues. Exosome-mediated signaling pathways under hypoxic conditions have been reported to cause angiogenesis, invasion, metastasis, drug resistance, and immune escape. Recently, the programmed cell death ligand-1 (PD-L1) has been reported to reside as a transmembrane protein in tumor exosomes. Exosomal PD-L1 was shown to suppress T cell effector function in the TME and cause drug resistance to immune checkpoint therapy. This review provides an update about the pivotal role of tumor-derived exosomes in drug resistance to chemotherapy and immunotherapy, particularly under hypoxic conditions. Emerging strategies that target the exosomes in the hypoxic TME to enhance the antitumor efficacy are discussed.
Emerging insights to lung cancer drug resistance
Authors: Su Chunxia
Published: June 2022

Lung cancer remains the malignant tumor with the highest morbidity and mortality in China, with non-small cell lung cancer (NSCLC) accounting for 80%-85% of cases. Nowadays, the treatment pattern of NSCLC has evolved toward precision management with the development of molecular targeted therapy and immunotherapy. However, the median overall survival for patients with metastatic NSCLC, unfortunately, remains less than three years. Drug resistance is the bottleneck to preventing drugs from playing a further role, and the mechanistic study of drug resistance is the prerequisite for new regimen development. This Special Issue pays special attention to drug resistance in the treatment of NSCLC. We received and published several excellent articles regarding this topic. We hope that, through this Special Issue, we can have a deep understanding of the existing problems, the underlying mechanism, and the future solutions and that the publication of this Special Issue can bring some inspiration to readers.
Implementation of STEM Integrated Project Based Learning (PjBL) to Improve Problem Solving Skills
Authors: Putri Maharani Ayu Nurdiana , Dwikoranto Dwikoranto
Published: June 2022

The 4Cs are skills that emphasize learning across the 21st century (Critical thinking, Communication, Collaboration, Creativity). Problem-solving, one of the 21st century's skills, developed by implementing PjBL-STEM learning models. PjBL-STEM learning focuses on developing students' ability to be more engaged, innovative, and open to the idea of concepts learnt through project-based activities that incorporate STEM aspects in real life. The study's goal is to examine how PjBL-STEM learning improves problem-solving skills. The research method used was quantitative research through a one-group pre-experimental design with pretest and posttest. A total of 35 students from class XI IPA 2, SMA X Muhammadiyah Surabaya, participated in the study.  This study uses purposive sampling to consider students' abilities and conditions of delivery of subject matter. The study's results (N-gain) were 0.59, classified as "medium".  According to the findings of this study, Learning the PjBL-STEM model has been sufficient for enhancing problem-solving abilities in dynamic fluid materials. The characteristics of the PjBL-STEM learning model that focuses on the 'student-centred model' significantly influence problem-solving skills. The advantages of this model should be accompanied by improvement of educational facilities and teaching skills in the learning process in order to create a balanced learning environment
Inquiry-based Blended Learning Design for Physics Course: The Effectiveness and Students’ Satisfaction
Authors: Suana Wayan
Published: June 2022

This paper describes the effects of implementing inquiry-based blended learning (IBBL) design on students' learning achievement and satisfaction in an undergraduate physics course. This study employed the one group pre-test – post-test experiment design with a sample of 32 students who took an undergraduate level basic physics course. Learning design and devices applied in this research have been validated by three experts in physics education. 'Schoology', a virtual learning management system, was used as the online learning platform. One cycle of inquiry phases was conducted in the blended learning format of ‘pre-online–face to face–post-online learning’. The data were collected through tests, a scale, and a questionnaire. The test consisted of 35 multiple-choice questions with five alternative answers. It was designed to measure students’ abilities in remembering, understanding, applying, and analyzing. The satisfaction scale ranging from 1 (strongly disagree) to 5 (strongly agree) consisted of 21 items and covered the attractiveness, ease of use, and benefits of learning using the learning products. Furthermore, the questionnaire consisted of six open-ended questions asking about the obstacles and benefits students faced during the learning activities. The results showed that the students’ learning outcomes increased sufficiently. Besides, students’ satisfaction with the learning design and materials was also positive. These initial findings imply that inquiry-based learning (IBL) may be implemented in physics teaching using a blended learning format that can be more effective and efficient.
Inevitable changes in the IT industry. Training in the conditions of the fifth industrial revolution (industry 5.0)
Authors: Petrenko Anatolii
Published: June 2022

The rapid evolution of digital technologies is bringing significant changes to society. The environment and human values are becoming more diverse and complex. The society is entering a new phase of its development called Industry 5.0, a human-centered one that realizes both economic development and entertainment with social issues where people can enjoy a high quality of life. Such a major transformation of the new type of a society significantly affects the organization of education as the basis of Industry 5.0. The paper examines these inevitable changes, covering all the essential elements of personalized education and requiring the combined efforts of all key stakeholder groups, including governments, education and training providers, industry, support bodies, the wider community and, most importantly, students themselves.
System analysis of the problem of establishing the authenticity and authority of painting works
Authors: Martynenko Andrii , Tevyashev Andriy , Kulishova Nonna , Moroz Boris
Published: June 2022

Cultural values have long been the objects of crimes, among which the export from the state stands out. Falsification hides artworks from customs control and its detection requires a long examination using a variety of methods of analysis. This article discusses the task of verifying painting’s authenticity during customs inspection. A two-stage procedure is proposed, which includes a quick check based on the analysis of painting’s images and a longer museum expertize. To implement the image analysis, it is proposed to use an intelligent decision-making system, which is based on a classifier that implements the k-nearest neighbors algorithm. A set of features to describe painting’s properties is formed, metrics for calculating the similarity measure on objects in the course of classification is proposed. To train an algorithm, a dataset is proposed, which includes paintings by world and European artists, as well as Ukrainian painters from different centuries.
Analysis of Blockchain in the Healthcare Sector: Application and Issues
Authors: Odeh Ammar , Keshta Ismail , Abu Al-Haija Qasem
Published: June 2022

The emergence of blockchain know-how currently presents the opportunity for the health sector to adopt such technologies in electronic health records. Blockchain assists in maintaining and sharing the relevant medical records of the patient with the relevant group of healthcare providers and the hospital. Numerous specific applications include traceability of drug and patient monitoring or Electronic Health Records (EHR). While Blockchain assists in maintaining and sharing the relevant medical records of the patient with the relevant group of healthcare providers and the hospital, it is important to note that the moral consciousness of the healthcare professionals is the main guide of the moral consciousness is ethics. This paper presents an overview of the application of blockchain in the healthcare and medical sector, highlighting the specific challenges and concerns. The study adopted a systematic review of secondary literature in answering the research question.
Integrated Surveillance System for Controlling COVID-19 on a University Campus, 2020‒2021
Authors: Meredith Genevive R. , Osman Marwan , Cazer Casey L. , Cummings Kevin J. , Hecht Jason , Madsen Cecelia G. , Santacrose Laura B. , Dubovi Abigail S. , Clarkberg Marin , Johnson Tyler , Fitzpatrick Maria D. , Parrilla Lara , Li Yihong , Francis Lorraine , Weisfuse Isaac B. , Travis Alexander J. , Jones Anne C. , Warnick Lorin D. , Koretzky Gary A.
Published: June 2022

To minimize the impacts of COVID-19 and to keep campus open, Cornell University’s Ithaca, NY, campus implemented a comprehensive process to monitor COVID-19 spread, support prevention practices, and assess early warning indicators linked to knowledge, behaviors, and attitudes of campus community members. The integrated surveillance approach informed leadership and allowed for prompt adjustments to university policies and practices through evidence-based decisions. This approach enhanced healthy behaviors and promoted the well-being and safety of all community members. (Am J Public Health. 2022;112(7):980–984. https://doi.org/10.2105/AJPH.2022.306838 )
An Enhanced Understanding of Culture-Negative Periprosthetic Joint Infection with Next-Generation Sequencing
Authors: Goswami Karan , Clarkson Samuel , Phillips Caleb D. , Dennis Douglas A. , Klatt Brian A. , O’Malley Michael J. , Smith Eric L. , Gililland Jeremy M. , Pelt Christopher E. , Peters Christopher L. , Malkani Arthur L. , Palumbo Brian T. , Lyons Steven T. , Bernasek Thomas L. , Minter Jon , Goyal Nitin , McDonald James F. , Cross Michael B. , Prieto Hernan A. , Lee Gwo-Chin , Hansen Erik N. , Bini Stefano A. , Ward Derek T. , Shohat Noam , Higuera Carlos A. , Nam Dennis , Della Valle Craig J. , Parvizi Javad ,   on behalf of the Orthopedic Genomics Workgroup
Published: June 2022

Background:

The challenges of culture-negative periprosthetic joint infection (PJI) have led to the emergence of molecular methods of pathogen identification, including next-generation sequencing (NGS). While its increased sensitivity compared with traditional culture techniques is well documented, it is not fully known which organisms could be expected to be detected with use of NGS. The aim of this study was to describe the NGS profile of culture-negative PJI.

Methods:

Patients undergoing revision hip or knee arthroplasty from June 2016 to August 2020 at 14 institutions were prospectively recruited. Patients meeting International Consensus Meeting (ICM) criteria for PJI were included in this study. Intraoperative samples were obtained and concurrently sent for both routine culture and NGS. Patients for whom NGS was positive and standard culture was negative were included in our analysis.

Results:

The overall cohort included 301 patients who met the ICM criteria for PJI. Of these patients, 85 (28.2%) were culture-negative. A pathogen could be identified by NGS in 56 (65.9%) of these culture-negative patients. Seventeen species were identified as common based on a study-wide incidence threshold of 5%. NGS revealed a polymicrobial infection in 91.1% of culture-negative PJI cases, with the set of common species contributing to 82.4% of polymicrobial profiles. Escherichia coli, Cutibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus ranked highest in terms of incidence and study-wide mean relative abundance and were most frequently the dominant organism when occurring in polymicrobial infections.

Conclusions:

NGS provides a more comprehensive picture of the microbial profile of infection that is often missed by traditional culture. Examining the profile of PJI in a multicenter cohort using NGS, this study demonstrated that approximately two-thirds of culture-negative PJIs had identifiable opportunistically pathogenic organisms, and furthermore, the majority of infections were polymicrobial.

Level of Evidence:

Diagnostic Level II. See Instructions for Authors for a complete description of levels of evidence.
Synovial Fluid and Serum Neutrophil-to-Lymphocyte Ratio
Authors: Varady Nathan H. , Schwab Pierre-Emmanuel , Kheir Michael M. , Dilley Julian E. , Bedair Hany , Chen Antonia F.
Published: June 2022

Background:

Septic arthritis (SA) is a musculoskeletal emergency for which prompt diagnosis and treatment are critical. However, traditional diagnostic criteria of a synovial fluid (SF) white blood-cell count (WBC) of >50,000 cells/mm3 or >90% polymorphonuclear leukocytes (%PMN) are not particularly sensitive or specific for the diagnosis of SA. Furthermore, prognostic markers are lacking. The purposes of this study were to assess the discriminative ability of the SF neutrophil-to-lymphocyte ratio (NLR) in the diagnosis of SA and of the serum NLR in the prognosis of SA.

Methods:

A multi-institution, retrospective study of 598 patients with native shoulder, hip, or knee SA in 2000 to 2018 was conducted. SF-NLR was calculated from the arthrocentesis cell count with differential. Receiver operating characteristic curves were analyzed, and the optimal threshold of SF-NLR for SA diagnosis was determined using the Youden index. Results were compared with traditional SF diagnostic criteria. Similar analyses assessed the association of serum NLR with 90-day treatment failure and mortality for the subset of patients with confirmed hip or knee SA and with serum complete blood-cell counts with differentials (n = 235). Results were compared with traditional serum prognostic markers (WBC, C-reactive protein [CRP], and erythrocyte sedimentation rate [ESR]).

Results:

The SF-NLR (area under the receiver operating characteristic curve [AUC], 0.85 [95% confidence interval (CI), 0.82 to 0.88]) was significantly more accurate for an SA diagnosis than SF-WBC (AUC, 0.80 [95% CI, 0.76 to 0.83]; p = 0.002) and SF-%PMN (AUC, 0.81 [95% CI, 0.77 to 0.84]; p = 0.01). The optimal threshold of SF-NLR was 25 (78% sensitivity and 81% specificity), compared with >50,000 cells/mm3 for SF-WBC (56% sensitivity and 80% specificity) and >90% for SF-%PMN (65% sensitivity and 78% specificity). Elevated serum NLR was independently associated with 90-day treatment failure (odds ratio [OR], 7.04 [95% CI, 3.78 to 13.14]; p < 0.001) and mortality (OR, 7.33 [95% CI, 2.00 to 26.92]; p = 0.003); elevated serum WBC and CRP were also associated with treatment failure, and WBC, CRP, and ESR were not associated with mortality.

Conclusions:

This study provides compelling data on the superior diagnostic and prognostic ability of serum NLR and SF-NLR for SA compared with current clinical standards. Given that this biomarker requires no additional cost or time to return than current laboratory tests already being performed, pending validation, it can readily be used to aid clinicians in the diagnosis and prognostication of SA.

Level of Evidence:

Diagnostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Long-Term Clinical Outcomes and Implant Survivorship of 151 Total Ankle Arthroplasties Using the HINTEGRA Prosthesis
Authors: Yoon Yeo Kwon , Park Kwang Hwan , Park Jae Han , Lee Wonwoo , Han Seung Hwan , Lee Jin Woo
Published: June 2022

Background:

Few studies have investigated long-term clinical outcomes of a mobile-bearing total ankle arthroplasty (TAA) system. This study analyzed long-term outcomes of TAA using the HINTEGRA prosthesis at a single, non-developer center.

Methods:

Primary TAAs were performed on 213 ankles in 194 patients, and 151 consecutive ankles [71%] in 136 patients with a minimum follow-up of 10 years after the primary TAA were included in this study. Clinical results were assessed using a visual analog scale (VAS) pain score, the American Orthopaedic Foot & Ankle Society (AOFAS) Ankle-Hindfoot Scale score, the Ankle Osteoarthritis Scale (AOS) pain and disability subscores, and ankle range of motion. Prosthesis survivorship, reoperations, and risk factors were also evaluated.

Results:

The mean follow-up was 135.5 months (range, 120.0 to 204.0 months). All clinical scores and ankle range of motion improved significantly from preoperatively to 2 years, 4 to 6 years, and ≥10 years after TAA (p < 0.001). A total of 43 ankles (28.5%) required revision procedures, with the most common reason being periprosthetic osteolysis (32 ankles [21.2%]). The overall implant survivorship was 93.5% in Kaplan-Meier survival analysis at the mean follow-up of 11.3 years after the TAA.

Conclusions:

TAA using the HINTEGRA prosthesis with careful follow-up observation and appropriate adjunct procedures for the treatment of end-stage ankle arthritis produced satisfactory clinical results, which were maintained at a follow-up of ≥10 years, and resulted in 93.5% of implant survivorship.

Level of Evidence:

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.