bluuebunny/crossref_metadata_2025 huggingface dataset:
The precise chemotherapy guided by the expression of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes versus the classic chemotherapy in the treatment of breast cancer: a comparative effectiveness research
Authors: LI Juncheng , Sun Peng , Huang Tao , He Shengdong , Li Lingfan , Xue Gang
Published: November 2019

Objective: ERCC1, RRM1, TUBB3, TYMS and TOP2A gene have been shown to be associated with chemotherapeutic drug resistance. And the aim of the present study was to evaluate the guiding significance of the above genes expression in the selection of precise chemotherapy regimen for breast cancer.
Methods: 140 well-matched patients with breast cancer, including 70 from the precise chemotherapy group and 70 from the classic chemotherapy group, were retrospectively analyzed. In the precise chemotherapy group, the mRNA expression levels of ERCC1, RRM1, TUBB3, TYMS and TOP2A in breast cancer tissues were measured by the multiplex branched DNA liquidchip (MBL) technology before chemotherapy. And the precise chemotherapy regimen was developed according to the detection results. As a comparison control, patients from the classic chemotherapy group were given TEC(Docetaxel+Epirubicin+Cyclophosphamide) regimen. Survival analysis were performed by the Kaplan–Meier method. The prognostic factors of breast cancer were identified via the Cox proportional hazards model. Adverse reactions were evaluated in the light of the National Cancer Institute Common Toxicity Criteria 4 (NCI-CTC version 4.0).
Results: The median follow-up time was 67.5 months (1.0–84.0 months). Compared with the classic chemotherapy group, the DFS and OS of the precise chemotherapy group were significantly longer (DFS:77.4 months vs 67.1 months,P=0.039;OS: 81.4 months vs 75.4 months,P=0.031), and the incidence of grade 2 or 3 palpitations and chest tightness was lower (12.9% vs 27.1%,P=0.035). The chemotherapy strategy guided by genetic detection was an independent protection factor for DFS (HR=0.389,95%CI:0.153,0.989,P=0.047), but not an independent protection factor for OS (HR=0.340,95%CI:0.107,1.078,P=0.067). Metastasis of axillary lymph nodes was an independent risk factor for DFS(HR=7.049,95%CI:1.813,27.410,P=0.005). Additionally, the independent risk factor affected DFS(HR=3.378,95%CI:1.074,10.624,P=0.037) and OS(HR=8.140,95%CI: 1.666,39.759,P=0.010) was poor endocrine therapy compliance.
Conclusions: Combined detection of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes expression for guiding precise chemotherapy can improve treatment efficacy and reduce unnecessary toxicity.
INVESTIGATION OF THE INFLUENCE OF SESAME ANTIOXIDANTS ON THE OXIDATIVE STABILITY OF PROVITAMIN A
Authors: Ananieva Valeriya , Belinska Anna
Published: November 2019

Microbiological oil solutions of provitamin A (β-carotene) as a dietary supplement are not widely used due to their low oxidation stability. The aim of research is determination of the effect of sesame antioxidants on the oxidative stability of provitamin A in oil solutions. The peroxide number of vegeTable oils is determined by the standard method by the titrimetric method. The value of the period of induction of oil oxidation is determined graphically from the growth curves of peroxide numbers. The content of tocopherols in oils is determined by spectrophotometric method. The content of sesamol and sesamoline in oils is determined by the colorimetric method. The oxidative stability of oils is determined using the accelerated “active oxygen” method. To plan the experiment and process the data, mathematical methods are applied using the software Microsoft Office Excel 2003. The oxidation stability of blended oils (a mixture of sesame, high oleic, sunflower and corn refined oils) and its components is investigated. Blended oil has a lower oxidative stability than sesame oil, but higher than corn and high oleic sunflower. The oxidative stability of the blend is enhanced by the antioxidant content of sesamol and sesamoline. The content of the above antioxidants, as well as the amount of tocopherols, is studied in blended oils. The oxidation stability of the obtained solution of provitamin A in blended oils is investigated. The period of induction of oxidation of blended oils with the addition of 0.2 % β-carotene increases by 1.3 times compared with the period of induction of the original blended oil. Blended long-life oil is recommended to be used to stabilize fat-soluble biologically active compounds.
FABRICATION OF PhC STRUCTURES BY USING NANOIMPRINT LITHOGRAPHY AND THEIR OPTICAL PROPERTIES
Authors: Nevrela Juraj , Kuzma Anton
Published: November 2019

The contribution deals with creating structure, which have unique properties for influencing the spectrum of light. Since these structures exhibit the period under the diffraction limit of visible light or UV radiation, they can’t be fabricated by standard photolithography. As a result, this nanoscale structure must be prepared with progressive nanostructure patterning technology known as nanoimprint lithography (NIL). Especially, in our work UV-nanoimprint lithography was used. Considering preservation of low production costs, which plays a crucial role in the industry, the UV-nanoimprint lithography will be best suit for this purpose. Using this technology result with respect to reproducibility and uniformity of created nanostructure has been achieved. Ability of influencing light spectrum for nanostructures with the period of 800 nm and 600 nm with various feature size were presented with observation and simulation also.
THE CURRENT STATUS OF THE E-GOVERNMENT PROJECT IN JORDAN AND ITS BENEFITS AND ADVANTAGES
Authors: Alhawawsha Mohammad , Anisimov Anatoly
Published: November 2019

Today, it is expected that governments will respond to public needs, manage public funds efficiently and transparently, and adapt to social changes. In this transitional process, public administration gains inspiration from private companies, goal-driven management, and custom. At the same time, the resistance to such a large organizational change is enormous. The huge size of the government makes it slow to change, especially when the implementation of e-government is only one of the many challenges that the government must deal with e-oriented policies. The quest to implement e-government projects is motivated by the fundamental policy goals of (i) increased effectiveness, efficiency, and information quality; and (ii) improved interaction mechanisms, and in turn better governance tools. In Jordan, e-services initiative is the heart of the e-government. Therefore, the ICT sector is best served and is able to deliver e-government services in an integrated manner, as a result since 2000, many national ICT projects have been launched to sustain and support the e-government program.
THE INFLUENCE OF TECHNOLOGICAL FACTORS ON THE PROPERTIES OF BASALT FIBER WHEN USED IN THE MANUFACTURE OF FLEXIBLE HEAT AND SOUND INSULATING PRODUCTS
Authors: Berdnyk Oksana
Published: November 2019

Analysis of energy efficiency and operational safety of technological equipment of industrial enterprises, engineering networks, buildings and structures, building structures in many sectors of the economy, including the housing and industrial sectors, causes interest in the use of high-tech, environmentally friendly heat and sound insulation materials with enhanced performance properties. One of the relevant representatives of these materials is basalt fibers and their use as raw materials in the production of flexible heat and sound insulating products. It is known that the chemical composition of the initial melt equally affects the physicochemical and mechanical properties of basalt fibers. The main influence factors, including the chemical composition, are the thermal past of the melt, the method for producing basalt fiber and the conditions for the formation of its structure. These factors determine the structural characteristics of the fiber and, as a consequence, its physicochemical characteristics. The degree of fiber strength is directly determined by its chemical composition and production method. The greatest strength of the fiber is obtained by ensuring the perfect fiber structure in the absence of ruptures of siliceous chains.
INVESTIGATION OF THE IMPORTANCE OF STARUNIA PALEONTOLOGICAL LOCATION OF THE PLEISTOCENE FAUNA OF THE RHINOCEROSES AND THE MAMMOTHS FOR QUATERNARY GEOLOGY
Authors: Radlovska Kateryna , Kachala Sofiia
Published: November 2019

The first finds of mummified carcasses of the hairy rhino, mammoth, horse, roe deer and other animals were carried out at a depth of 12 m when passing the mines for the production of ozokerite near the village. The expedition of the Academy of Skill from Krakow, when passing a mine at a depth of 17 m, found the remains of 3 more hairy rhinos. There were also numerous bones of small vertebrates (rodents), artichokes, numerous insects, beetles, parasitic worms, slag, butterflies, spiders, snails, vascular plants, seeds and branches of dwarf birch, alder, and other representatives of tundra flora. After the earthquake in the Vrancha Mountains (Romania), the first and still unique mud volcano in the Carpathians, which gave the Starunia paleontological location a new "sound", arose on the ozokerite deposit. An important result was the discovery of the most desirable area, where the remains of giant mammals and even the Cro-Magnon Pleistocene could still be found at the depths. All the numerous interdisciplinary traces of Polish and Ukrainian scientists confirm the uniqueness of Starunia on a global scale, requiring the preservation and further study of paleontological finds and the only mud volcano in the Carpathians. Such findings can only be made by organizing the Starunia geodynamic ground International Ecological and Tourist Center «Geopark Ice Age».
DEVELOPMENT OF A WEB SERVICE FOR FORMING A SEMANTIC KERNEL OF A WEBSITE BASED ON DATA MINING METHODS
Authors: Mironenko Dmitry , Balalayeva Elena
Published: November 2019

A technique has been developed for the formation of the semantic core of a site for Internet resources with already generated or dynamically generated content. A mathematical model based on data mining methods is given. For analysis and further research, an information technology is developed – a web service. The main users of this web service will be SEO specialists, for whom it will become a convenient tool. This web service relies on data mining methods and statistics on the use of search queries obtained from the Google Search interface. Integration of the data allows to qualitatively select the necessary keywords and give a list of the most optimal, relating to the subject of the site. For research, the site of the Department of Computer Science of the Azov State Technical University was selected. During the experiment, a list of keywords and phrases was obtained. The words in the list are sorted in decreasing order of performance. The automated formation of the semantic core eliminated the subjectivity of the SEO specialist when selecting words and phrases, the time spent on its formation is ten times less than the manual semantic analysis. The result set included only those words and phrases that are often used in the content and are most significant. Using Google Search to adjust the list of words allows to match words with search queries and select those for which users are looking for information. The web service has a flexible mechanism for regulating (limiting) the number of keywords in the result set. The main advantage of using this service is that only those words and phrases fall into the semantic core, in response to which there is something to offer visitors on the site.
Effect of Aqueous Warionia saharae Extract on Lipid and Glucose Metabolism in Normal and Diabetic Rats
Authors: Hebi Morad , Haidani Ahmed El , Eddouks Mohamed
Published: November 2019

Objective:

The aim of the study was to evaluate the hypolipidemic and antioxidant properties of aerial parts aqueous extract of Warionia saharae (APAE of W. saharae) in normal and streptozotocin (STZ) induced-diabetic rats. Additionally, the quantitative and qualitative analysis for the presence of different phytochemical constituents in the APAE of W. saharae was performed.

Methods:

The effects of oral administration of APAE of W. saharae (5 mg/kg) on the plasma Total Cholesterol (TC) and triglyceride (TG) levels were measured in both normal and diabetic rats. Moreover, the antioxidant capacity was realized by the method of DPPH. Total polyphenol as x of the APAE of W. saharae were determined.

Results:

APAE of W. saharae showed a strong hypolipidemic and antihyperglycemic effects both in normal and in STZ induced diabetic rats. On the other hand, APAE of W. saharae showed a potent antioxidant activity and revealed inhibitory activity. Moreover, the quantitative determination of total polyphenol and flavonoid contents showed high contents of these phytochemicals. Concerning the qualitative analysis several classes of chemicals have been found.

Conclusion:

APAE of W. saharae (5 mg/kg) shows the potential cholesterol and glucose lowering activity as well as antioxidant properties in both normal and STZ-induced diabetic rats.
Methods of elimination of rails increased damage in the area of weld joints
Authors: Shur E. A. , Fedin V. M. , Borts A. I. , Ronzhina Yu. V. , Fimkin A. I.
Published: November 2019

Rail weld joints from electric-contact welding in stationary and fi eld conditions, as well as those from aluminothermic welding are weak points on tracks that are easily damaged compared with rails outside the weld joints. Currently, these weak points are the defects connected with lack of penetration in the welding area, burns at the points of poor contact of the rail foot with the current-carrying contact tips, or with defects of the weld joint machining after welding, as well as the local hardness reduction in areas affected by heat after welding, and local heat treatment after welding. Elimination of wide areas of reduced hardness at the weld joint points producing saddles, cracks, and chipping, and promoting rails damage next to such joints is a major challenge for increasing the serviceability of weld joints. This study introduces three avenues for elimination of increased damage of rails at weld joints including:

• Improvement of technology and equipment for electriccontact welding and local heat treatment after welding in the stationary and fi eld conditions.

• Development of technology and equipment for induction welding in the stationary and fi eld conditions.

• Development of technology and equipment for differentiated induction tempering of rails preliminary welded in strings 800 m long.
New method for control of fuel injection initiation and fuel combustion in diesel locomotive engines
Authors: Kon’kov A. Yu. , Kon’kova I. D.
Published: November 2019

Adequate regulation of diesel engine fuel equipment is an important factor affecting the economic and ecological indicators of diesel engine and its reliability. The fuel injection advance angle deviates from the best value during operation for several reasons, requiring timely control and regulation of the parameter. This issue is crucial for diesel engines with individual high-pressure pumps like the diesel locomotive engines. This study presents a new method for indirect determination of the fuel injection advance angle based on analysis of the pressure fi rst-order derivative signal — pressure change rate. This method eliminates the need for additional measurements like the crankshaft rotation angle or piston position, and therefore, exhibits potential for the development of easy and reliable devices for online diagnostics. The study also briefl y analyzes control methods for the fuel injection advance angle used in operating diesel-electric locomotives in Russia. The results of theoretical research performed through mathematical modeling for the locomotive diesel engine 1А-5D49 is also examined. A dimensionless criterion is proposed based on results calculated from the experiment, which is determined by the value of the pressure change rate signal at representative points allowing calculation of the fuel injection advance angle using simple linear dependence. Verifi cation of the proposed method demonstrates good agreement of the results with existing methods.
Estimation and test assessment of the rail pads effect on the indicators of dynamic impact of the rolling stock on the track in the joint area
Authors: Kaplin V. N. , Myslivets M. N. , Sidorova E. A. , Polunina E. A.
Published: November 2019

Increasing axial loads including the development of heavy movement on Russian railroads network require the best solutions for improvement of the railway track structure. Research by Russian and international scientists indicates that rail elastic pads reduce vibrations transferred from reinforced concrete sleepers to crashed stone, including the joint area. This study examines possibilities of using rail pads for reducing the dynamic effects of the rolling stock on the track in the joint area. Assessment of the rail pads construction material shock-absorbing properties was conducted considering the elastic properties of the rail support with static and dynamic loads. Results of mode ling the elastic properties of the rail support with rail pads of different rigidities using the software complex “Universal mechanism” are presented. The results were used as basis for calculation of indicators of dynamic interaction of the track and rolling stock at the joint using the coeffi cient establishing the link between bendings of the solid rail and the rail with joint. The expediency of using rail pads at the place of the joint is justifi ed based on assessment of the results.

This study reveals that elastic rail pads based on isoprene rubbers are suitable for track structures that improve indicators of the track and rolling stock interaction. When using rubber pads, the growth of accelerations on the sleeper is less dependent on the speed, causing the track stability to increase. The results are supported by tests consistent with calculations and justify the necessity for further studies in this fi eld.
The Effect of annealing temperature on corrosion resistance and microstructure of Zr-Sn-Nb-Fe alloy
Authors: Zhao G. , Tiba Zsolt , Menyhárt József
Published: November 2019

The Ti-2Al-2.5Zr titanium alloy plate in beta phase water quench at different times of the reentry after annealing is implemented while primary phase number and size distribution of samples are obtained. This research is carried out on corrosion behavior in 3.5% [mass fraction] NaCl solution. Experimental study showed that after the beta phase water quenching Ti-2Al-2.5Zr titanium alloyed after 500 oC annealing when partial recrystallization happened. There seems to be lots of tiny dispersion in the alloy that was annealed with its samples of six-party [HCP] structure of Ti, Zr, Al phase 2 with the dimension below 100 nm. Reaching 500 oC when the rate of annealing at a primary phase of the sample at 550 oC is low 90% of the primary phase is less than 100 nm. The changing of the rule of present decreasing also triggers little difference overall. Precipitation in the process of annealing Zr [Nb,Fe,Cr] 2is less that proves to be good for corrosion resistance.
From the Epistolae et Evangelia (c. 1540) to the Espejo divino (1607)
Authors: Laird Andrew
Published: November 2019

In 1536, fifteen years after the Spanish conquest of Mexico, the Imperial College of Santa Cruz was founded in Santiago Tlatelolco, an Indian enclave to the north of Mexico City. The students at the college, who were drawn from native elites, received an advanced education in Latin from Franciscan missionaries. The present discussion will explain why such a training was provided to those indigenous youths, and clarify the nature of their accomplishments (1). A discussion of the translations of biblical texts into Nahuatl made at the College of Santa Cruz (2) will be followed by a survey of original religious texts produced there in the Mexican language, many of which had identifiable Latin precedents (3). The concluding section then offers some tentative general reflections on the part played by Latin Christian humanism in shaping early Nahuatl literature, arguing that it bears some comparison to the way Latin had already underscored the development of vernacular literature in early modern Europe (4).
The Application of Internet-Based Sources for Public Health Surveillance (Infoveillance): Systematic Review
Authors: Barros Joana M , Duggan Jim , Rebholz-Schuhmann Dietrich
Published: November 2019

Background

Public health surveillance is based on the continuous and systematic collection, analysis, and interpretation of data. This informs the development of early warning systems to monitor epidemics and documents the impact of intervention measures. The introduction of digital data sources, and specifically sources available on the internet, has impacted the field of public health surveillance. New opportunities enabled by the underlying availability and scale of internet-based sources (IBSs) have paved the way for novel approaches for disease surveillance, exploration of health communities, and the study of epidemic dynamics. This field and approach is also known as infodemiology or infoveillance.

Objective

This review aimed to assess research findings regarding the application of IBSs for public health surveillance (infodemiology or infoveillance). To achieve this, we have presented a comprehensive systematic literature review with a focus on these sources and their limitations, the diseases targeted, and commonly applied methods.

Methods

A systematic literature review was conducted targeting publications between 2012 and 2018 that leveraged IBSs for public health surveillance, outbreak forecasting, disease characterization, diagnosis prediction, content analysis, and health-topic identification. The search results were filtered according to previously defined inclusion and exclusion criteria.

Results

Spanning a total of 162 publications, we determined infectious diseases to be the preferred case study (108/162, 66.7%). Of the eight categories of IBSs (search queries, social media, news, discussion forums, websites, web encyclopedia, and online obituaries), search queries and social media were applied in 95.1% (154/162) of the reviewed publications. We also identified limitations in representativeness and biased user age groups, as well as high susceptibility to media events by search queries, social media, and web encyclopedias.

Conclusions

IBSs are a valuable proxy to study illnesses affecting the general population; however, it is important to characterize which diseases are best suited for the available sources; the literature shows that the level of engagement among online platforms can be a potential indicator. There is a necessity to understand the population’s online behavior; in addition, the exploration of health information dissemination and its content is significantly unexplored. With this information, we can understand how the population communicates about illnesses online and, in the process, benefit public health.
A Brief Mobile-Augmented Suicide Prevention Intervention for People With Psychotic Disorders in Transition From Acute to Ongoing Care: Protocol for a Pilot Trial
Authors: Depp Colin , Ehret Blaire , Villa Jennifer , Perivoliotis Dimitri , Granholm Eric
Published: November 2019

Background

People with serious mental illnesses (SMIs) are at exceptionally high risk for lifetime suicidal ideation and behavior compared with the general population. The transition period between urgent evaluation and ongoing care could provide an important setting for brief suicide-specific interventions for SMIs. To address this concern, this trial, SafeTy and Recovery Therapy (START), involves a brief suicide-specific cognitive behavioral intervention for SMIs that is augmented with mobile phone interactions.

Objective

The primary aim of this pilot trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of the intervention.

Methods

A 6-month pilot trial with 70 participants with a diagnosis of bipolar disorder, schizophrenia or schizoaffective disorder, and current active suicidal ideation were randomized to START or START with mobile augmentation. START consists of 4 weekly sessions addressing early warning signs and triggers, symptoms influencing suicidal thinking, and social relationships. Recovery planning is followed by biweekly telephone coaching. START with mobile augmentation includes personalized automated cognitive behavioral therapy scripts that build from in-person content. Participants were evaluated at baseline, 4 weeks (end of in-person sessions), 12 weeks (end of telephone coaching), and 24 weeks. In addition to providing point estimates of feasibility and acceptability, the primary outcome of the trial was the change in severity of suicidal ideation as measured with the Scale for Suicide Ideation (SSI) and secondary outcome included the rate of outpatient engagement.

Results

The trial is ongoing. Feasibility and acceptability across conditions will be assessed using t tests or Mann-Whitney tests or chi-square tests. The reduction of SSI over time will be assessed using hierarchical linear models.

Conclusions

The design considerations and results of this trial may be informative for adapted suicide prevention in psychotic disorders in applied community settings.

Trial Registration

ClinicalTrials.gov NCT03198364; http://clinicaltrials.gov/ct2/show/NCT03198364

International Registered Report Identifier (IRRID)

DERR1-10.2196/14378
The cost-effectiveness of algorithms and artificial intelligence applied in health care: A scoping review research protocol (Preprint)
Authors: Aboueid Stephanie , Liu Rebecca Hsin-Ling , Sabesan Piraveena
Published: November 2019

BACKGROUND

Given the rapid digitization of health care and abundance of available data, there is a great interest in how to leverage these advancements into evidence-based practice. Algorithms and artificial intelligence have the potential to improve health care, reduce costs, and contribute to evidence-based practice. An in-depth examination of the available evidence is needed to elucidate the cost-effectiveness of algorithms and AI techniques applied in health care.

OBJECTIVE

The goal of this scoping review will be to map the literature on the cost-effectiveness of algorithms and AI techniques applied in health care. The current review protocol provides an overview of the steps taken to complete the review.

METHODS

The PRISMA-Scoping Review checklist will be used to guide the reporting of the scoping review. Three main concepts include: 1) health care costs; 2) algorithms and AI techniques; and 3) cost-effectiveness analysis. The following databases will be used: PubMed, Scopus, ACM Digital Library, IEEE, Google Scholar, Econlit, OpenGrey, and ProQuest Dissertations and Theses. Two researchers (SA and RHL) will independently screen the titles, abstracts, and full texts, while a third researcher (PS) will negotiate any discrepancies, until consensus is reached.

RESULTS

Article retrieval, data extraction, and interpretation are currently underway.

CONCLUSIONS

Findings from the review may provide invaluable insights on the cost-effectiveness of algorithms and AI techniques applied in health care. Given that health care dollars are scarce, it is important to know which algorithms and AI techniques are worth the upfront investments. As a result, decision-makers will be able to identify which algorithms or AI technique would be of value for their specific context. This review will also identify key knowledge gaps in the literature and will provide next steps for future research.

CLINICALTRIAL

Not applicable - this is a scoping review.
Effect of a Health System–Sponsored Mobile App on Perinatal Health Behaviors: Retrospective Cohort Study (Preprint)
Authors: Cawley Caroline , Buckenmeyer Hannelore , Jellison Trina , Rinaldi Joseph B , Vartanian Keri B
Published: November 2019

BACKGROUND

Pregnancy mobile apps are becoming increasingly popular, with parents-to-be seeking information related to their pregnancy and their baby through mobile technology. This increase raises the need for prenatal apps with evidence-based content that is personalized and reliable. Previous studies have looked at whether prenatal apps impact health and behavior outcomes among pregnant and postpartum individuals; however, research has been limited.

OBJECTIVE

The primary objective of this study is to assess whether the use of a health system–sponsored mobile app—Circle by Providence—aimed at providing personalized and reliable health information on pregnancy, postpartum recovery, and infant care is associated with improved health outcomes and increased healthy behaviors and knowledge among users.

METHODS

This observational study compared app users and app nonusers using a self-reported survey and electronic medical records. The study took place over 18 months and was conducted at Providence St. Joseph Health in Portland, Oregon. The sample included patients who received prenatal care at one of seven Providence clinics and had a live birth at a Providence hospital. Recruitment occurred on a rolling basis and only those who completed the survey were included. Survey respondents were separated into app users and app nonusers, and survey responses and clinical outcomes were compared across groups using univariate and adjusted multivariate logistic regression.

RESULTS

A total of 567 participants were enrolled in the study—167 in the app user group and 400 in the nonuser group. We found statistically significant differences between the two groups for certain behavior outcomes: subjects who used the app had 75% greater odds of breastfeeding beyond 6 months postpartum (P=.012), were less likely to miss prenatal appointments (P=.046), and were 50% more likely to exercise 3 or more times a week during pregnancy (P=.04). There were no differences in nutritional measures, including whether they took prenatal vitamins, ate 5 fruits or vegetables a day, or drank caffeine. We found no differences in many of the infant care outcomes; however, there was an increase in awareness of “purple crying.” Finally, there were no significant differences in measured clinical health outcomes, including cesarean births, length of hospital stays (in minutes), low birth weight infants, preterm births, small-for-gestational-age births, large-for-gestational-age births, and neonatal intensive care unit stays.

CONCLUSIONS

The use of the Circle app, which provides access to personalized and evidence-based health information, was associated with an increase in certain healthy behaviors and health knowledge, although there was no impact on clinical health outcomes. More research is needed to determine the impact of mobile prenatal apps on healthy pregnancies, clinical health outcomes, and infant care.
How Can Artificial Intelligence Make Medicine More Preemptive? (Preprint)
Authors: Iqbal Usman , Celi Leo Anthony , Li Yu-Chuan Jack
Published: November 2019

UNSTRUCTURED

In this paper we propose the idea that Artificial intelligence (AI) is ushering in a new era of “Earlier Medicine,” which is a predictive approach for disease prevention based on AI modeling and big data. The flourishing health care technological landscape is showing great potential—from diagnosis and prescription automation to the early detection of disease through efficient and cost-effective patient data screening tools that benefit from the predictive capabilities of AI. Monitoring the trajectories of both in- and outpatients has proven to be a task AI can perform to a reliable degree. Predictions can be a significant advantage to health care if they are accurate, prompt, and can be personalized and acted upon efficiently. This is where AI plays a crucial role in “Earlier Medicine” implementation.
Presentación. Nuevos capitalismos y transformaciones territoriales en la región andina
Authors: Baud Michiel , Boelens Rutgerd , Damonte Gerardo
Published: November 2019

This presentation introduces a special issue that analyzes the new territorial configurations taking shape in the Andean region under the developmentalist governments of the 21st century. The new territorial projects seek to increase the extraction of resources, the transference of crucial products on local level, and economic development. This remodeling transforms the techno-natural, cultural and political orders and creates new ‘capitalisms’ that facilitate knowledge production on, exploitation of, and control over local societies. This special issue analyzes the practical and political expressions of these new forms of social and ecological (re)territorialization.
Measuring system for amperometric chemical sensors using the three-electrode technique for field application
Authors: Hernández P.R. , Galán C.A. , Morales A. , Alegret S.
Published: November 2019

A portable and low cost measuring system for amperometric chemical sensors using the three-electrode technique was developed. This technique allows chemical sensors to work with currents higher than ten microamperes. The system was based on a potentiostat operation, completed with an I-V converter and signal conditioning circuits. The instrument was evaluated comparing calibration curves of hydrogen peroxide, proving several amperometric chemical sensors and biosensors, to those obtained from a very expensive commercial equipment. Good linearity and sensibility as well as low noise measurements were obtained. Moreover, because the reduced size and low cost, the instrument allows to be used directly in field applications.
Guaranteeing asymptotic zero intersampling tracking error via a discretized regulator and exponential holder for nonlinear systems
Authors: Castillo-Toledo B. , Obregón-Pulido G.
Published: November 2019

In this paper we present the design of a robust discretized controller based in the theory of regulation for nonlinear systems. In the general command tracking and disturbance rejection problem, it is known that a sample data controller using zero order holder may only guarantee asymptotic tracking at the sampling instances. We show that by means of a so-called exponential holder, we are able to guarantee asymptotic zero output tracking error, not only in the sampling instant, but also between these instant. Some considerations on the design of exponential holders are presented. The application in simulation to some typical nonlinear systems shows the good performance of the proposed scheme.
Modeling an improved method for double modulation photo reflectance experiments
Authors: Hernández M. , Ivanov R.
Published: November 2019

This paper describes an improved method to be used in double modulation photo reflectance experiments, in order to reduce the influence of parasitic effects in the useful signal. The method uses the inner and outer sections of a single chopper disk to modulate the monochromator and the laser beam, eliminating the need of complex electronic filters, and two additional PIN photodiodes for scattered light compensation. The method has been numerically simulated using LabVIEW in order to investigate the influence of the modulator finite switching time and the finite resolution of the digital acquisition system. Results show that a relative error less than 1% can be achieved.
An optimal Chaotic Bidirectional Communicator for Hidden Information, based on Synchronized Lorenz Circuits
Authors: Núñez R.
Published: November 2019

An Optimal Chaotic Bidirectional Communicator for Hidden Information (OCBCHI) is presented. Its realization is based on a Standard Chaotic Bidirectional Communicator for Hidden Information (SCBCHI), that uses two Lorenz synchronized circuits with an open-loop explicit method. All the chaotic dynamics of the circuits were studied and analysed using DSP techniques. Regarding to our real-time application, -on bidirectional audio communications field-, the optimum conclusion was to make the synchronization and the hidden communication of the private information by the lower chaotic dynamic variable and the most higher chaotic dynamics variables, respectively. By the complete characterization of the bidirectional channels, we got the minimum parameters (i.e., time and spectrum magnitude) of the private information that it must have just to make a confidential and robust communication.
High- efficiency class E power amplifier using SI-GE HBT technology
Authors: Tirado-Méndez J.A. , Jardón-Aguilar H.
Published: November 2019

One of the most important goals of RF circuit designers is improving efficiency and autonomy in handsets for personal communications. Currently, low-level voltage supplies are used to avoid big weight and volume. Besides, autonomy and efficiency are closely linked to the energy consumed by the circuits. Power Amplifier (PA) is one of the circuits, which spends more energy from the battery. Improving the PA efficiency, handset performance is also improved. Previous publications have mentioned the difference of power amplifiers where the circuit output works as I) a current source or II) as a switch. The class E power amplifiers are devices whose output works as a switch achieving great performance and high power efficiency, reaching, in an ideal case, 100 % of efficiency. In this paper, a low-level voltage class E power amplifier is analyzed, designed, simulated, built and characterized, using a silicio-Germains HBT transistor as an active element. The circuit was optimized using a harmonic balanced simulator (Microwave Office Â® [1]). 70% power efficiency was measured after an optimizing procedure, although better performance can be expected with an improved switching transistor and more precisely lumped elements. The prototype was designed to operate at 900 MHz and fed with 2.4 V, but it is well known that low-level polarization voltages affect efficiency, linearity, power gain, bandwidth, noise figure, as well as cost in RF circuits. However the class E PA reported in this paper reaches high efficiency, high power gain as well as a good bandwidth, with lowlevel polarization voltage.
Editorial
Authors: Morla Elbi
Published: November 2019

No precisa de resumen.
Inequality beyond networking: personal networks and mobilization of contacts by young job seekers in Barcelona
Authors: Muntanyola Saura Dafne , Barranco Oriol , Vacchiano Mattia
Published: November 2019

How young job seekers mobilize their contacts in the labour market? We look at mobilization of personal networks of young adults in Barcelona. We consider the strength of ties and status homophily as mecha- nisms of personal networks as for the consolidation of social capital. Our qualitative analysis of 18 in- terviews with job seekers explores their personal networks and labour market trajectories. We applied Social Network Analysis (SNA). Our analysis of social capital indicates the existence of a relation between the cultural and economic capitals of job seekers and the compositional features of their networks. Re- sults show how networks are similarly heterogeneous in terms of strength of ties, and mostly homophilous in educational levels. But these similarities in terms of social capital come with sharp inequalities in the patterns of mobilized contacts and their success in finding a job. These differences can be explained by the type and volume of capitals of job seekers. Those with better positions in the social structure and sta- ble trajectories seem to mobilize fewer contacts more efficiently, getting better outcomes.
Usaha Orang Tua dalam Peningkatan Pendidikan Anak di Pidie
Authors: Umar Juairiah
Published: November 2019

Peran serta orang tua dalam mendidik anak adalah kunci keberhasilan orang tua dalam membentuk kepribadian anak. Anak cenderung meniru setiap hal yang dilihat dari orang tuanya. Tujuan penelitian ini adalah untuk mengetahui peran orang tua dalam mendidik anak di Pidie dan untuk mengetahui kendala-kendala yang dihadapi orang tua dalam mendidik anak di Gampong Rumia, Tamping Tunong, Pulo Baroh Kecamatan Indrajaya dan Kecamatan Delima Pidie . Metode penelitian ini adalah kualitatif. Populasi penelitian ini adalah seluruh orang tua atau kepala keluarga (KK) yang ada di tiga Gampong, Rumia, Tamping Tunong, Pulo Baroh sebanyak 269 KK, sampel penelitian ini diambil sebanyak 15 KK dari keseluruhan KK yang dipilih secara acak. Teknik pengumpulan data dilakukan melalui wawancara, observasi dokumentasi. Data dalam penelitian ini dianalisis dengan metode deskriptif kualitatif. Hasil penelitian menunjukkan bahwa orang tua di Gampong Rumia, Tamping Tunong, Pulo Baroh, memberikan keteladanan yang baik kepada anak-anaknya, keteladanan yang diberikan meliputi pendidikan keimanan, pendidikan akhlak, pendidikan intelektual, pendidikan psikis dan juga pendidikan sosial. Orang tua juga berusaha sebagai pembimbing yang baik, yaitu melalui pengawasan terhadap anak baik tentang kegiatan sehari-hari maupun tentang tugas-tugas sekolah yang diberikan guru. Usaha orang tua selanjutnya sebagai motivator bagi anak-anaknya agar lebih giat dalam belajar dengan menasehati anak terhadap hal-hal yang baik dan menjauhi hal-hal yang buruk, selain itu dalam memotivasi anak orang tua di Gampong Rumia, Tamping Tunong, Pulo Baroh, meningkatkan kedisiplinan anak dalam belajar. Kendala yang dihadapi orang tua di Gampong Rumia, Tamping Tunong, Pulo Baroh dalam mendidik anaknya adalah kemajuan teknologi yang sulit dikontrol oleh orang tua, apalagi ketika anak-anaknya menggunakan Hp android yang dapat mengakses internet tanpa mampu dikontrol oleh orang tua. Selain itu, orang tua juga mengakui bahwa lingkungan pergaulan anak juga ikut menjadi kendala dalam mendidik anak-anak mereka.
RAHASIA ZIKIR ASMAUL HUSNA DALAM MEWUJUDKAN KELUARGA SAKINAH
Authors: Uce Loeziana
Published: November 2019

Islam memberikan salah satu jalan kepada umatnya untuk meraih ketentraman hidup melalui pernikahan. Dengan pernikahan ini pasangan suami isteri diharapkan akan berada dalam susana damai, tentram dan bahagia. Terjalin keharmonisan di antara suami isteri yang saling mengasihi dan menyayangi sehingga masing-masing pihak merasa tertram, damai dan bahagia dengan kehadiran pasangan hidupnya.. Suasana keluarga yang tentram, damai dan bahagia ini diistilahkan dengan keluarga sakinah. Keluarga Sakinah , dalam kehidupan sehari-hari masyarakat muslim terutama di Indonesia, bukanlah sesuatu yang asing. Ungkapan ini terasa sangat akrab ditelinga masyarakat dan bahkan telah dijadikan slogan umum untuk mengungkap doa dan harapan ingin diraih oleh pasangan yang akan ataupun tengah membina rumah-tangga. Kendati demikian, ternyata ungkapan ini hanya akrab ditelinga. Realitanya banyak yang belum memahami baik secara definitif maupun makna, tentang gambaran, konon lagi wujud dan persyaratannya sehingga banyak pasangan yang menemukan banyak kesulitan dalam menggapai Keluarga sakinah sebagaimana yang dimaksudkan dalam al-Qur’an.Pada hakikatnya setiap permasalahan ada solusinya demikian juga dengan permasalahan ini. Sesungguhnya Islam telah memberikan pembelajaran-pembelajaran melalui Al-Quran dan Rasulnya tentang konsep sebuah keluarga agar keluarga menjadi sakinah yang tentram penuh kedamaian. Hal ini menjadi yang dilakukannya sebuah penelitian di International University of Asmaul Husna (IUAH). Dari hasil penelitian tersebut, ternyata keluarga Sakinah yang penuh ketentraman dan kedamaian salah satu caranya dapat diwujudkan dengan cara berzikir, menggunakan nama-nama Allah yang terdapat didalam ke 99 Asmaul Husna.
GAMBARAN BENTUK KEKERASAN DALAM RUMAH TANGGA YANG DIALAMI PEREMPUAN PENYINTAS
Authors: Nisa Haiyun
Published: November 2019

Permasalahan kekerasan dalam rumah tangga merupakan hal yang masih kerap dialami oleh khususnya perempuan. Beberapa penyintas mencoba menyelesaikan permasalahan yang terjadi dalam rumah tangganya dengan melaporkan tindak kekerasan yang dialami pada pusat layanan maupun pihak yang berwajib. Penyintas menyampaikan perlakuan kekerasan yang diterimanya dengan tujuan untuk mendapatkan penanganan yang tepat. Terdapat beberapa bentuk kekerasan yang terjadi dalam rumah tangga, antara lain fisik, psikologis, seksual dan penelantaran ekonomi. Perempuan penyintas mengalami berbagai bentuk kekerasan, baik yang disadari maupun tidak disadari. Perempuan penyintas belum mengenali dengan cukup baik bentuk kekerasan yang dialaminya, penyintas menganggap bahwa kekerasan dalam rumah tangga hanyalah kekerasan fisik, sehingga kerap mengabaikan bentuk kekerasan lainnya.
COMPETÊNCIAS MATEMÁTICAS NA BNCC: IMPLICAÇÕES CURRICULARES
Authors: Kipper Daiane , De Oliveira Cláudio José , Gomes Lívia Bittencourt
Published: November 2019

O presente trabalho tem por objetivo analisar as Competências específicas de Matemática para o Ensino Fundamental da Base Nacional Comum Curricular (BNCC). Para isso, selecionamos como material de pesquisa excertos do referido documento. Como referencial teórico-metodológico assumimos o pensamento de Michel Foucault e Zigmunt Bauman e suas interlocuções com o campo da Educação Matemática. Com base nas análises do material, compreendemos que a Matemática, enquanto componente curricular, é apresentada como um conhecimento a ser aplicado e utilizado pelo aluno nessa autorresponsabilização e flexibilização, pois cabe a ele encontrar formas de utilizá-la. A aplicação e a solução de problemas são apontadas como competências a serem desenvolvidas na Educação Básica e efetivadas pelo currículo escolar. As discussões em torno das competências elucidadas pela BNCC apresentam que o referido documento está a serviço da nova configuração econômica mundial. O documento vem a instituir uma forma de matematizar e agir, como sendo importante para os processos de aprendizagem.
O TRANSTORNO DE DÉFICIT DE ATENÇÃO E HIPERATIVIDADE NOS PERIÓDICOS DA EDUCAÇÃO FÍSICA E EDUCAÇÃO
Authors: Santos Crislene Gois , Da Silva Renato Izidoro
Published: November 2019

Trata-se de uma de revisão bibliográfica acerca das relações entre Transtorno de Déficit de Atenção e Hiperatividade (TDAH) e educação, segundo publicações veiculadas em periódicos das áreas acadêmicas da Educação Física e da Educação. Para tanto, com base em uma literatura de comentadores e pesquisadores do tema, realizamos um estudo teórico-conceitual e comparativo acerca do processo histórico de definição dos conceitos de TDAH de acordo com os dois principais documentos internacionais que versam sobre o assunto: o DSM-5 e do CID-10. A revisão sistemática implicou um trabalho dividido nas fases de eleição dos periódicos, seleção dos trabalhos, análise categorial, discussão e interpretação dos dados. Consideramos que os resultados retratam um contexto insipiente, ensaístico e assistemático de pesquisas, cujos apontamentos dos especialistas se limitam a aconselhamentos de domínio subjetivo no enfrentamento dos problemas, além de insipientes perspectivas metodológicas para seu tratamento.
A INTERDISCIPLINARIDADE INTRÍNSECA NAS AÇÕES DESENVOLVIDAS NO PIBID
Authors: Tucci de Carvalho Ana Márcia Fernandes , Lugle Andreia Maria Cavaminami , De Oliveira Sandra Regina Ferreira
Published: November 2019

Esta pesquisa analisa questões relativas à efetivação de abordagens interdisciplinares nos diferentes subprojetos em desenvolvimento no PIBID/UEL. Para tanto, aprofundamos o estudo da temática em formação de professores e no conceito de interdisciplinaridade. Teoricamente, abordamoscomo a interdisciplinaridade é apresentada nos documentos oficiais sobre o PIBID, logo a escolha metodológica foi a análise documental. Empiricamente, coletamos dados junto aos relatos dos participantes de um evento e afunilamos no estudo de um projeto desenvolvido na área de Matemática,com o tema Cultura Africana. A análise dos dados aponta que a interdisciplinaridade presente no PIBID/UEL concretiza-se a partir de projetos e/ou temas sob a regência do professor de áreas específicas. Colocamo-nos frente ao desafio da necessidade de compreender tais ações como transdisciplinares e expandi-las.