bluuebunny/crossref_metadata_2025 huggingface dataset:
Unraveling the impact of development strategies on employee productivity and performance
Authors: Rahman Md. Azizur
Published: July 2024

Purpose: Explore the complicated world of financial services as we rigorously investigate employee performance within the exclusive corridors of bKash Limited. The study, which is based on recognized organizational theories, seeks to evaluate the subtle impact of elements such as employee experiences, growth and development plans, workload, tools and systems, and recognition with incentives on employee productivity and overall organizational performance. Methodology: This study takes a quantitative approach, employing structural equation modeling (SEM) to examine data obtained from 301 bKash workers. Likert scale replies are included in the survey, which was disseminated online. Stratified sampling guarantees that all employment positions are represented, and hypotheses are investigated to determine the correlations between the variables being examined. Findings: The findings show that employee productivity plays a substantial mediating role in the relationships between employee experiences, growth and development plans, workload, recognition with incentives, and overall organizational success. Notably, tools and systems had no statistically significant influence on productivity, which might be attributed to difficulties such as hierarchy-related interruptions, potential breakdowns, and security concerns. Originality: This study adds to the current literature by offering a thorough examination of the relationship between organizational development methods, employee experiences, and productivity. It uncovers novel insights, notably about the various effects of tools and systems on employee productivity, offering light on the organizational complexities that influence performance. Practical Implication: These insights can be used by practitioners to improve organizational procedures. Recognizing the value of pleasant employee experiences, strategic growth goals, and successful recognition campaigns may boost employee productivity and, as a result, overall organizational performance. The research contributes to practical organizational leadership by providing sophisticated insights into the factors that shape employee outcomes in the workplace.
OPERATIONAL AND ADMINISTRATIVE FUNCTIONS OF DRUG ENFORCEMENT UNIT (DEU): BASIS FOR RESTRUCTURING THE FRAMEWORK OF DEU
Authors: Paraon-Bueno Arvie , Dausan Alrien F. , Dalugdog Wilfredo D.
Published: July 2024

Objective: This study was done to describe how the PNP Drug Enforcement Unit carries out its mandated operational and administrative functions.
 
Theoretical Framework: This study is anchored on the Theory of Multidimensional Approach which explains the process of assessing and implementing an approach such as methods, tactic, and strategy that consists of more than one feature/design to address a situation or problem that is considered complex or needs to be assessed from several points of view.
 
Method: In this study, the researchers used generic qualitative research, utilizing a grounded theory. Purposive sampling was used in selecting and identifying the participants of the study. A total of eight (8) participants were selected to describe the administrative and operational functions of the selected DEU. The data collection was done using the unstructure interview guide validated by the expert in the field. Ethical considerations
 
Results and Discussion: Themes were derived and analyzed, falling into five (5) main themes. They are as follows: 1) conundrums of insufficiency, 2) insufficiency reverberates ineffectiveness, 3) insufficiency breeds inefficiency, 4) labyrinth for development, and 5) taming of the flock.
 
Research Implications: The PNP DEU within their territorial jurisdiction are generally considered the center of the police responses to drug trafficking and use. Thus, they must mount the most sophisticated investigations techniques against drug traffickers. It is for this reason that they should have continuing training which are essential for their development.
 
Originality/Value: This study provides bases for restructuring the present framework of the PNP DEU. As it encourage that strategic shift from the existing framework to a restructured framework incorporating the improvements suggested as necessary by the participants.
Effect of access to sanitation on Urinary Tract Infections in urban women, Maharashtra, India
Authors: Devane-Padalkar Ashwini ,   Shelter Associates, Pune, Maharashtra, India, Kale Smita , Joshi Pratima ,   Shelter Associates, Pune, Maharashtra, India,   Shelter Associates, Pune, Maharashtra, India
Published: July 2024

Background: Women and girls have restricted access to sanitation in India. This leads to various health issues, especially for women and girls living in slums/settlements. This study aims assessment of urinary tract infections among women and girls who have restricted access to sanitation and compares the prevalence after the installation of household toilets. Along with the prevalence this study also examines the alterations in behaviors associated with access to sanitation. Materials and Methods: A pre and post-intervention study was conducted among women (n=1711) residing in slums across four cities in Maharashtra.The intervention included the installation of household toilets. Data on the individual characteristics of women, housing area/conditions, access to sanitation facilities, behaviors adopted by the women/girls that could be associated with UTI symptoms, and reported symptomatic UTI in the previous one month were gathered through a structured tool using the mobile application. Results: The prevalence of UTI among women and adolescent girls living in slums was 12.8% pre-intervention and 2.9% post-intervention. In the unavailability of the individual toilets, women and girls have altered their routine habits related to taking dinner, toilet use after dark (24.9%) and avoiding drinking water and liquid intakes (12.15%) to avoid frequent toilet visits. All these behavioral adaptations were found significantly associated with the presence of UTI. Conclusion: The study demonstrates that the installation of toilets in households improve sanitation-related behavior and menstrual and vaginal hygiene.
Outcome of antibiotic treatment in patients with abdominal trauma at the hospital in Ceilândia
Authors: Rosales Rolando Gutierrez , de Abreu Filho Jandui Gomes , Santana Karoliny Araujo , da Silva Nailton Gomes , Rocha Déborah de Fatima Diniz , de Paula Mozart Borges , Andrade Bruno Bessa , Rosa Kenya Correa , Sanches Matheus Savindo Batista
Published: July 2024

Infections generate complications capable of causing morbidity and mortality in trauma patients. As a measure to prevent infections, the administration of antibiotics should be early. However, the use of antibiotics for a long time is not recommended, since there is no evidence of a favorable outcome, in addition to increasing health care costs. Due to the need to prevent infections in trauma patients, it is important to adopt strict control measures with the implementation of effective strategies to improve health care for these patients. The aim of this study was to evaluate the impact of antibiotic use in trauma patients in a hospital in Brasilia. This research is an observational cross-sectional investigation, based on a retrospective approach through the extraction of data from the health information system "TrackCare". The participants of this research comprise patients with abdominal trauma who underwent surgical treatment from January to December 2021. It is observed that almost half of the 93 patients were assigned to receive antibiotic therapy or antibiotic prophylaxis. Within this selected group, the main antimicrobial agent chosen was Unasyn, a combined composition of Ampicillin with Sulbactam, covering approximately 31% of cases. In this context, it is urgent to consider that the selection of the antimicrobial agent is not only based on its efficacy, but also on its adequacy to the particularities of the clinical picture presented by the patient.
Study of the art of facial expressions in the emotion of irony
Authors: César Carla Patrícia Hernandez Alves Ribeiro , Guedes-Granzotti Raphaela Barroso , Sordi Claudia , da Silva Kelly
Published: July 2024

Irony, regardless of its subtype, is routinely used in human communication. Verbal, vocal, and non-verbal resources are used to express the irony. In this chapter, the objective is to present a literature review on using irony through facial expression. According to the results obtained, the face can express irony, highlighting the contradiction between oral speech and the facial expression itself, which helps the receiver understand that the speech is ironic. There are still scientific gaps on the subject, and more researchers must investigate the topic.
Spatial distribution of patients with pressure injuries treated at a teaching hospital
Authors: Musse Juliana de Oliveira , Braga Cristina , Marreira Marcelo , dos Reis Maria José , Douradinho Christian , Capeloa Cristina Nunes , Menezes João Carlos de Andrade , Ocon Carlos Alberto , Isabella Adriana Paula Jordão , Pitanga Fernanda Sebastiana Mendes , Muniz Claudia Cristina Soares , Ribeiro Filho Alfredo , Lima Lidiane Souza , Santos Gleyce Kelly de Brito Brasileiro , Aragão Neylor Rodrigo Oliveira , Torres João Pedro Santos , Olímpio Aloísio
Published: July 2024

Introduction: Pressure injury (PF) is characterized by pressure exerted mainly on bony prominences, or even related to the use of medical devices. As epidemiological aspects are still scarce in the country, it is appropriate to produce studies that delimit the information for a better characterization of this public health problem, with extraterritorial dimensions. Geoprocessing is a revolutionary technology that encompasses the most diverse disciplines, data, equipment, analysis and interpretations from certain locations and geographic data, thus obtaining maps and/or spreadsheets with information relevant to that region that, when used in the health area, allows the identification and mapping of risks and injuries that affect the population. Objective: To demonstrate the technical experience of spatial demarcation and geoprocessing of patients with pressure injuries treated at a teaching hospital in the state of Sergipe. Method: A descriptive epidemiological study was carried out from a data sheet of patients with pressure injuries treated by the Skin Care Service team of a teaching hospital in Sergipe, between 2018 and 2022. Georeferencing and geoprocessing were developed in conjunction with Google Maps and Google Earth software. Results: The study sample consisted of 215 patients with pressure injuries (PF) in which the age group that stood out was the elderly (54.8%), followed by adults (40.0%). It is noted, in the spatial representation, that most of the patients with PL were residents of Greater Aracaju (n=130), followed by the East of Sergipe (n=23) and Central Agreste (n=18). Most of the LPs were acquired prior to admission to the institution studied (55.8%), while the others (44.2%) appeared during the hospital stay. Conclusion: In view of the analysis presented, it was possible to verify that most patients affected by PLs are men and elderly, and that the Greater Aracaju regional was the one that stood out the most because it concentrated most of the patients with PL, whether pre-existing or acquired at hospitalization.
Association between polymorphisms in the gene encoding the vitamin D receptor, lipid profile and anthropometric parameters in elderly Brazilians
Authors: Nunes Ivone Freires de Oliveira Costa , de Carvalho Cecilia Maria Resende Gonçalves , Silva Gabriella Magalhães , dos Santos Gleyson Moura , da Silva Maria Eduarda Raielly , Silva Elane Natielly da Conceição , de Araújo Nauale Lopes , dos Santos Lynda Sthefanny Alves , Sousa Laura Beatriz Guimarães , Lodoro Gleicer Vívian da Silva , Gomes Ruth Hellen do Nascimento , Val Sarah Celeste Rodrigues de Sousa
Published: July 2024

Polymorphisms in the vitamin D receptor gene are associated with the severities of several diseases, including overweight and cardiovascular disease. In addition, vitamin D is an important determinant of health and has several functions in bone homeostasis and in various physiological and metabolic mechanisms. From this perspective, this study aimed to evaluate whether there is an association between the genetic variants Fok1 (rs2228570) and Bsm1 (rs1544410) with circulating metabolic markers of the lipid profile and anthropometric measurements in the elderly. This is a cross-sectional study conducted with 173 elderly people from Teresina, Piauí State, Brazil, whose sociodemographic and health characterization occurred through interviews. 25-hydroxyvitamin D [25(OH)D] was measured by chemiluminescence. The cut-off values used as a reference for serum lipids were from the Update of the Brazilian Guideline on Dyslipidemias and Prevention of Atherosclerosis. Genotyping was performed using the restriction fragment length polymorphism technique. The results showed that there were no statistically significant differences between the association of VDR FokI and BsmI gene polymorphisms with BMI, blood pressure and vitamin D concentrations. However, elderly carriers of the BsmI genotype, specifically Bb heterozygotes, were associated with lower values of triglycerides and HDL-cholesterol.
Perception of organizational support, knowledge management and intention to turnover in workers in the city of Natal – RN
Authors: Sena Jefferson Vitoriano , Formiga Nilton Soares , Santiago Fabiana P. , Sena Adelmaria C. , de Oliveira Eduardo Sinedino
Published: July 2024

The professional-organizational environment has revealed for organizational management a close relationship between structure and economic functionality, advantage in competitiveness associated with financial incentives and work function, as well as the influence of motivational and punitive variables on workers when tasks are not fulfilled. The phenomenon of turnover in organizations is not something new, as it is linked to the restructuring and dissolution of traditional organizational functional policies, such as job security, positions, and salaries. On the one hand, the way organizations generate and support their employees would probably be able to reduce the pace of turnover and make the policy of retaining professional talent more consistent; on the other hand, the efficient management of information processes, standards and knowledge related to the quality of the organizational system would be able to provide workers with both a more effective management of knowledge, as well as less intention to leave the organization or request a transfer of sector. These conditions would contribute to a better performance in the work environment and interpersonal relationships with a view to productivity and organizational efficiency. In this case, this study aims to verify the influence of organizational support on knowledge management and these on the intention of turnover in workers of public and private organizations in the city of Natal-RN.
Conventional treatment in the removal of microcontaminants
Authors: Pessoa Eliomar Gotardi
Published: July 2024

Water treatment plants have been commonly designed to promote high removal of particulate matter and microorganisms, with a significant predominance of conventional potabilization technology, comprising the stages of coagulation, flocculation, sedimentation or flotation, filtration and disinfection in different tanks.
Climatic characteristics in the Serra do Sincorá Geopark, in Chapada Diamantina, in the state of Bahia, Brazil
Authors: Meira Welison Nascimento , Almeida Fernanda da Silva , Veiga Artur José Pires
Published: July 2024

Climate studies and their elements are important, because in addition to research and weather forecasting, other sectors of the community need information about weather and climate, such as agriculture, aviation, civil defense, water resources management, navigation and the energy sector. In this sense, the present study aimed to analyze the variability of some elements of the climate of the Bahian municipalities of Andaraí, Lençóis, Mucugê and Palmeiras, the area of proposition for the creation of the Serra do Sincorá Geopark, in Chapada Diamantina, based on air temperature, rainfall and evapotranspiration in the perspective of understanding the behavior of the local climate and its possible effects in the region. For this analysis, specific time intervals were selected for each municipality, available at the National Institute of Meteorology (INMET) and Climatempo. The data were tabulated for statistical analysis of the behavior of the climate elements over the months and years, using as parameters the sum, minimum, maximum, average and the correlation between the meteorological variables, with the generation of climograms and comparative graphs. The relevance of the study lies in understanding the climatic variations of the municipalities in the proposed area of the Serra do Sincorá Geopark in relation to its climatic dimension, since the results may offer subsidies regarding environmental planning, in addition to a contribution to the local population, since there are few studies in the field of climatology in the region. With the analysis of meteorological data, it is proven that the municipalities of Andaraí, Lençóis, Mucugê and Palmeiras, due to climate factors, such as altitude, latitude and longitude, on a regional scale, influence the behavior of climate elements.
Aspectos clínicos e terapêuticos da infecção pelo HIV
Authors: Oliveira Carlos Walmyr de Mattos , Andrade Rômulo de Araujo , Rodrigues Alex Oliveira , Corsso Cristiane del , Valentim Laenne Ágata , Fliegner Thiago Franceschini , Leal Viviane Coelho , Santos Letícia Almeida , Barbosa Neucileny Melo , Lima Jessica Gomes , Cordeiro Quelvin Ribeiro , Penalva Matheus Cerqueira
Published: July 2024

A infecção pelo Vírus da Imunodeficiência Humana (HIV) permanece um desafio significativo para a saúde pública global, afetando milhões de pessoas em todo o mundo. Desde sua descoberta na década de 1980, a infecção pelo HIV evoluiu de uma doença frequentemente fatal para uma condição crônica gerenciável, graças aos avanços no entendimento da fisiopatologia viral e no desenvolvimento de terapias antirretrovirais (TARV) eficazes. Este trabalho apresenta uma revisão abrangente das estratégias clínicas e terapêuticas atuais para o manejo da infecção pelo HIV. A revisão foi conduzida utilizando uma abordagem sistemática em várias bases de dados biomédicas, incluindo PubMed, Scopus e Google Scholar, sem restrições de idioma ou data de publicação. Foram analisados estudos observacionais, ensaios clínicos, meta-análises e revisões sistemáticas que abordam tratamentos antirretrovirais, controle da carga viral, manejo de comorbidades e prevenção da transmissão. Os resultados destacam a eficácia das TARV combinadas em suprimir a carga viral, melhorar a contagem de células CD4+ e reduzir a incidência de infecções oportunistas e malignidades associadas ao HIV. No entanto, a adesão ao tratamento e a resistência viral são desafios contínuos. A gestão das comorbidades, como doenças cardiovasculares e distúrbios metabólicos, é essencial para melhorar a qualidade de vida dos pacientes. A revisão também aborda a importância do diagnóstico precoce e das estratégias de prevenção, como a profilaxia pré-exposição (PrEP) e a profilaxia pós-exposição (PEP), que têm se mostrado eficazes na redução da transmissão do HIV. No entanto, disparidades no acesso ao tratamento e ao diagnóstico, especialmente em países de baixa e média renda, continuam a ser um problema crítico. Conclui-se que, apesar dos avanços significativos, é necessário continuar a pesquisa e o desenvolvimento de novas terapias, bem como implementar políticas de saúde pública mais inclusivas para enfrentar os desafios emergentes associados à infecção pelo HIV. A revisão destaca a necessidade de uma abordagem integrada e multidisciplinar para o manejo eficaz da infecção pelo HIV, com o objetivo de alcançar uma resposta global mais eficaz e sustentável para esta epidemia de saúde pública.
Printed circuit board manufacturing and chemistry teaching under a CTSA approach
Authors: Benevides Raquel Rodrigues Teixeira , Gonçalves Jovane dos Santos , Vieira João Henrique
Published: July 2024

The contextualization of experimental activities based on the inclusion of students' daily lives and CTSA content provides a broader view of chemical phenomena, redefining the role of school in society, giving meaning to experimental activities and scientific content, contributing to the learning of scientific content and to the citizenship formation of students. Therefore, this article aims to present an activity for teaching oxidation-reduction reactions under a CTSA approach with the theme Printed Circuit Boards (PCB). In other words, the students built a PCB and CTSA content was built with them about the extraction of metals and the disposal of electronic equipment. This activity was part of the teaching project: "Experimental activities: science and technology in everyday life" developed at IFPR - Barracão Campus.
Moral harassment and the subjectivity of the contemporary worker: Analysis of the Ambev case
Authors: dos Santos Ayran Vinicius , Soldera Lucas Martins
Published: July 2024

This study explores the dynamics of contemporary work and its impact on workers’ mental health, focusing specifically on organizational culture and moral harassment. When corporate culture promotes cooperation and respect, it benefits employees’ well-being; on the other hand, competitive and precarious environments can increase the risk of mental disorders. The Ambev case illustrates how collective moral harassment practices can affect workers’ identity and well-being, highlighting the need for healthy organizational policies. The study uses a qualitative approach and the case study method to investigate this complex relationship, guided by the theory of Work-Related Mental Health (WRMH).
The use of essential oils as an alternative to performance-enhancing antibiotics in beef cattle: Literature review
Authors: Calegari Maria José , Marcon Werner Peter , Espadin Beatriz Pereira , Tateishi Simone , Fodra Aluisia Budin , Antoniazzi Matheus Augusto Santos , Bardini Inácio Zapparoli , Godinho Emmanuel Zullo , Fermino Caetano Dartiere Zulian
Published: July 2024

Brazilian livestock farming stands out worldwide as a leader in the production and export of meat, driven by a significant herd of approximately 234.4 million head, according to IBGE data from 2023. The beef cattle production cycle comprises three distinct phases: breeding, rearing and finishing, each culminating in the production of weaned calves, lean steers and fat steers, respectively. This activity, predominantly based on pasture due to tropical climatic conditions, faces challenges such as pasture degradation and forage seasonality, requiring the use of technologies such as growth-promoting additives to optimize production results. These additives, including antibiotics such as ionophores and non-ionophores, as well as essential oils, improve feed efficiency and contribute significantly to the national economy, although they raise debates about microbial resistance and environmental impacts
Burnout syndrome in the light of the executive secretarial professional
Authors: Costa Erick Raphael Pereira do Nascimento , Melquiades Camila Teles , Arruda Geyza D’Ávila
Published: July 2024

This study aims to identify and describe the perceptions of Executive Secretarial professionals about burnout syndrome. The study is relevant because this profession often involves high levels of stress due to the nature of the tasks and the expectations placed on these professionals. A descriptive study was conducted using a mixed-methods approach: quantitative and qualitative. The research applied questionnaires to a representative sample of Executive Secretarial professionals in different sectors, ages, and regions of Brazil. The study revealed that a significant proportion of the Executive Secretarial professionals surveyed had limited or inadequate knowledge about burnout syndrome. Many were unable to correctly identify the symptoms of the condition or understand its main risk factors. In addition, most were not aware of strategies for preventing and managing burnout syndrome. The results highlight the importance of providing additional training and education to Executive Secretarial professionals about burnout in order to improve their perceptive ability, how to prevent and deal with this condition. This can not only benefit mental health, but also contribute to a healthier and more productive work environment in the eyes of these professionals.
Millet as forage and silage in livestock farming
Authors: Tateishi Simone , Marcon Werner Peter , Calegari Maria José , Espadin Beatriz Pereira , Godinho Emmanuel Zullo , Fodra Aluisia Budin , Fermino Caetano Dartiere Zulian , Bardini Inácio Zapparoli , Antoniazzi Matheus Augusto Santos
Published: July 2024

This abstract was an analysis of articles on the use of millet in animal nutrition, its fixed and variable production costs, and its development as a forage crop in the central-western region of São Paulo. In recent studies, millet Pennisetum glaucum has been a prominent alternative as a forage crop for improving degraded soils with low organic matter content. Its ease of direct planting has promoted its use by livestock farmers as a potential substitute for corn in livestock farming as a forage crop and in animal feed. Millet cultivation is positive due to its low fixed cost, being financially more viable due to its short cycle, greater adaptability, good germination in the high temperatures of the central-western region of São Paulo, low water requirements and greater resistance in the dry season, making it an excellent option for planting in the off-season (autumn and winter). With roots reaching 3 meters, it easily extracts nutrients from the soil, increasing the accumulation of calcium, potassium and nitrogen in the upper layer of the soil, reducing the application of agricultural inputs, which reduces the final cost of production. As silage, it does not have antinutritional effects, such as tannin, despite its high crude protein content and digestibility. Nutrients extracted from the soil remain in the straw as it decomposes, returning to the soil; high biomass in the foliage; high nutritional content of the seeds; high seed production; adaptability to different levels of soil fertility; resistance to diseases and pests; suppression of weeds by physical effects; longer-lasting straw. Due to the above, the use of millet as silage has shown advantages due to the multifunctionality of its use in livestock. Although its metabolizable energy content is equivalent to that of corn and sorghum, its low water and agricultural input requirements reduce the total cost of production, requiring only planning in cultivation and supply to animals.
Professional education in radiology: Potential positions for graduates in resonance services in Rio de Janeiro linked to the Unified Health System
Authors: da Silva Bruno Fernandes , Ferreira Felippe Kelly , de Cerqueira Neto Joel Acioli , Suhett Julio Cesar Bernardo , de Jesus Bruno Marcenal , de Oliveira Juliana Silva , Gomes Alexandre dos Santos
Published: July 2024

Nuclear magnetic resonance (NMR) is an advanced technology for medical diagnosis, allowing the non-invasive study of internal organs through magnetic fields. The main components of an NMR equipment include the main magnet, gradient coils, radiofrequency coils, computer and image processing. These equipments are essential for image diagnosis, and it is essential to know their territorial distribution to benefit the population and guide future radiology professionals. The study analyzed the distribution of MRI equipments operating in the state of RJ, especially those affiliated with the SUS, aiming to identify job opportunities for graduates of professional courses in radiology.
Education and indigenous (re)existence through writing of the self-for a pedagogy of sensibilities: Dialogue between Paulo Freire and Maria Amélia Pinho Pereira
Authors: Ramos Viviane Kate Pereira , Pimentel Alexandre Simões
Published: July 2024

From the decolonial thinking originated at the end of the twentieth century, the importance of indigenous resistance practices promoted from the "taking of the word" will be problematized, a term coined by the philosopher Michel de Certeau, and appropriate in this research to refer to the development of research and literary productions carried out by indigenous researchers and writers in order to confront and re-signify the colonizing narratives about these peoples. pointing out how these productions contribute to thinking about a decolonial education, such as the school model proposed by the pedagogue Maria A. P. Pereira and her Education of Sensitivity. It is understood, based on Catherine Walsh, Paulo Freire, Márcia Kambeba, Daniel Munduruku and Albert Memmi, that the colonizer finds in scientific-intellectual knowledge devices of knowledge-powerthat underpin oppressive Eurocentric structures to justify exploitation, violence, inequality, inferiorization and discrimination, bases that still exert a strong influence on the various sectors of contemporary society. It is identified in the contributions of the aforementioned researchers that an educational model critical of scientism and the hierarchization of knowledge is possible from an educational praxis that dialogues with the diversities of knowledge and cultures, where education is liberating, promoting the overcoming of the dichotomy of the oppressor-oppressed as proposed by Freire, and is applied in the Education of Sensitivity promoted by the pedagogue Maria A. P. Pereira
Intracranial neoplasms in small animals: Literature review
Authors: da Cruz Anna Luiza Lara
Published: July 2024

Intracranial neoplasms are common tumors in the nervous system of older animals, diagnosed mainly by magnetic resonance imaging and tomography. The main types include meningioma, glioma and neuroepithelial tumors. Clinical signs vary according to the location of the tumor, including seizures, ataxia and behavioral changes. Treatment involves surgery, radiotherapy and chemotherapy to reduce the size of the tumor and relieve symptoms such as cerebral edema and increased intracranial pressure.
The importance of pharmacovigilance notifications in a teaching hospital: Experience report
Authors: dos Santos Adriano , Lima Silvana Andreia Molina , Fernandes Marcia Cercal , Gonçalves Simone Fernanda
Published: July 2024

Pharmacovigilance is an important activity for society. It contains a complex regiment in the hospital environment that aims at total patient safety as well as the analysis of problems related to the use of medications, risks that can be harmful to health during the hospitalization process. There are numerous errors in the use of medications, so applying the risk management tool in the establishment can be an alternative to ensure a safe process. In order to create risk prevention strategies, it is important to identify and analyze the causes of events and implement preventive actions before and after the occurrence. The objective of this work is to describe the importance of pharmacovigilance notifications for patient safety during the period of hospitalization in a teaching hospital. This is a qualitative, descriptive research of the actions developed by the hospital clinical pharmacist together with the multidisciplinary team to promote safe practices for the prevention of medication errors and reduction of harm. A well-developed and implemented management system in the service ended up generating the actions developed such as: review and training of the prescription, dispensing and administration protocol of medication; technical notes; implementation of the protocol based on the visual identification of medications; standardization of drug identification labels; change in electronic medical prescription of drugs, visual identification on packaging, training on pharmacovigilance; annual training with new residents and prescribing physicians. The strategic actions developed and implemented by the team served to create a safer environment, thus promoting safe processes and safe practices during the hospitalization period. The team's performance in creating strategies was important and enriching, pharmacovigilance is an important instrument in preventing any adverse events, encouraging reporting is extremely relevant and a key element in patient safety.
Content of Phenols, Flavonoids and Antihyperuricemic Activity of Leaves And Rhizomes of Smilax Purhampuy Ruiz
Authors: Soledispa Cañarte Pilar A. , Mangas Marín Raisa , Sarmiento Tomalá Glenda M. , Zavala ec Soledispa Byron E.
Published: July 2024

Introduction: Smilax purhampuy is traditionally used for the treatment of chronic gastritis, cystitis, arthritis and inflammation of the prostate; however, it lacks scientific studies that support its traditional use. Objective: To estimate the chemical composition and antihyperuricemic activity of hydroalcoholic extracts from leaves and rhizomes of S. purhampuy. Method: the dry material of leaves and rhizomes of the species was used for the elaboration of the extracts by maceration with 80 % hydroalcoholic solvent. Total phenols were quantified by Folin-Ciocalteu and total flavonoids by the aluminum chloride colorimetric method. Antihyperuricemic activity was evaluated in rats using the potassium oxonate induction model; the extracts were tested at doses of 125, 250 and 400 mg/kg and allopurinol 10 mg/kg was used as a positive control. The uric acid content in blood serum was quantified and the enzymatic activity of xanthine oxidase was determined. Results: in the phytochemical determinations, significant differences were observed in the content of each evaluated metabolite, fundamentally associated with the characteristics of each plant organ. The highest content of phenols (4.08 mg EAG/g) and flavonoids (1.01 mg EQ/g) was found in the leaf extract. The extracts of leaves and rhizomes showed a significant decrease in the levels of uric acid in blood serum (156.31 µmol/L y 167.58 µmol/L, respectively) and in the activity of the enzyme xanthine oxidase at all doses tested, being more marked in the extract of leaves at 400 mg/kg. Conclusions: the results provide the first findings of the antihyperuricemic potential of the species and make an important contribution to the knowledge of its chemical composition
Optimising emergency response: strategic integration of forensic toxicology into clinical laboratory protocols
Authors: Yaguargos Daza Anthony Javier , Moina Veloz Álvaro Paúl
Published: July 2024

The integration of forensic toxicology into clinical laboratory protocols proved crucial in improving emergency response, as it examined the harmful effects of chemical substances and their interaction with the body. Identifying the causative agent of poisoning was complicated by non-specific symptoms and the emergence of new psychoactive substances. These substances, designed to mimic the effects of drugs of abuse, were regulated internationally.According to Alza and Hancco, the use of illicit substances such as marijuana and cocaine was common in cases of domestic violence in Peru. Ponce Renata reported an increase in the use of these substances and alcohol in crimes in Riobamba, Ecuador.For a rapid and reliable response in emergencies, toxicological studies were needed to identify the causative agents and to collaborate with health workers. The timely availability of tests was limited, so this study was essential to establish cause-effect relationships and improve response protocols and the recognition and handling of toxic substances
The Existence of Solutions to Elliptic Equations with Multiple Critical Nonlinearities and Rellich Potentials
Authors: Zhou W.
Published: July 2024

In this paper, we investigate the Biharmonic problem that involves numerous critical non-linearities and Rellich potentials.
                                            \(\Delta^2 u-\mu_1 \frac{u}{|x|^4}-\mu_2 \frac{u}{|x-a|^4}=|u|^{2^*-2} u+\frac{|u|^{2^*(s)-2} u}{|x-a|^s} \quad \text { in } \Omega \backslash\{0, a\},\)
where \(\Omega\) is a smooth open bounded domain in \(\mathbb{R}^N(N \geq 5)\), \(2^*(s)\)=\(\frac{2(N-s)}{N-4}\), 0 <s <4 and \(\mu_i<\bar{\mu}=\left[\frac{N(N-4)}{4}\right]^2(i=1,2)\). We use Mountain-Pass theorem to prove the existence of a solution to the above problem.
Micro Target: MicroRNA Target Prediction and Validation with Experimentally Positive and Negative Examples
Authors: Das Shibsankar
Published: July 2024

MicroRNAs (miRNAs) usually controls the gene by binding to complementary sites of 3’ untranslated region of its target genes. Numerous criteria-based and machine learning approaches are available in the literature to predict miRNA–mRNA interactions, but most of them struggle with either high false positive or false negative rates and also don’t show good validation with experimentally validated positive and negative examples. Here we present microTarget, a new computational approach for identifying miRNA target genes which are based on complementarity score, thermodynamic duplex stability and also independent of conservation of target sites in related genomes. In this article, we validated our algorithm using positive and negative data from the literature in various human tissues, and our method outperformed existing computational methods such as miRanda, RNA22, and PITA. Receiver operating characteristic curves (ROC) and Matthew's correlation coefficient (MCC) were calculated using experimentally validated data, and they reveal that microTarget greatly improves miRNA target prediction compared to the three algorithms employed individually. Additionally, an F-score analysis demonstrated that microTarget greatly enhances the relevance of the other techniques. Thus, microTarget is a useful tool for biologists looking for miRNA targets and integrating them into biological contexts.
Evaluating the Effect of Live Brine Shrimp (Artemia franciscana) on Growth Performance in Ornamental Fish, Cyprinus rubrofuscus (Lacepede, 1803)
Authors: M. V. Aiswarya , S. Mary Mettilda Bai , R. Siva Santhiya , J. Vinoliya Josephine Mary , T. Citarasu , G. Uma , J. R. Anusha
Published: July 2024

Feeding is a critical factor for both cultured and ornamental fish species. This study aimed to evaluate the effects of live brine shrimp (Artemia franciscana) on the growth and biochemical composition of fish. In the present study, sixty days feeding trail was conducted on the growth performance of ornamental fish, koi carp (Cyprinus rubrofuscus). The type of food such as live feed, nutrient-enriched prepared feed and commercial feed exerted a significant impact on the growth and body composition of fish. The specific growth rate is high in live brine shrimp fed fishes followed by prepared food. After 60 days experiment showed that the maximum length and weight of live brine shrimp fed fishes were 7.5 ± 0.9 cm and 5.3 ± 1.7 gm, respectively. The survival rates of the fish were 100 % under all feeding groups. The biochemical profiles of the fish varied significantly between the different feeding regimes. These results suggest that live feed is more effective than pelletized feed for ornamental fish culture.
IMPLEMENTASI PROGRAM KELUARGA BERENCANA (KB) PRIA DI KECAMATAN AMUNTAI SELATAN KABUPATEN HULU SUNGAI UTARA
Authors: Berkatillah Akhmad
Published: July 2024

Berdasarkan observasi awal maka peneliti tertarik melakukan penelitian di desa Kayakah, Murung Panggang, dan Kota Raja. Alasan peneliti memilih desa ini salah satunya disebabkan lokasi yang mudah dijangkau sehingga membuat peneliti dengan sangat mudah untuk mendapatkan data-data dan informasi yang diperlukan, selain alasan tersebut alasan lain peneliti mengambil studi kasus di tiga desa tersebut adalah dikarenakan ketiga desa tersebut merupakan desa yang memiliki banyak penduduk diantara desa-desa lainnya yang ada di Kecamatan Amuntai Selatan Kabupaten Hulu Sungai Utara.
Berdasarkan pengamatan peneliti  lakukan dibeberapa desa yang terdapat di Kecamatan Amuntai Selatan Kabupaten Hulu Sungai Utara tentang rendahnya partisipasi pria dalam penggunaan alat kontrasepsi disebabkan oleh beberapa faktor
MINIMIZING RISK IN PROCESS SELECTION FOR MORE EFFECTIVE OPERATIONAL MANAGEMENT AT PT. MAYORA INDAH. TBK
Authors: Sangkala Masnawaty
Published: July 2024

This study examines the process of minimizing risks in employee selection to improve operational management at PT Mayora Indah Tbk. Established in 1977, PT Mayora Indah Tbk has grown from a local market in Jakarta to a global presence on five continents. This study analyzes the implementation of process selection for more effective operational management at PT Mayora Indah Tbk. Through a qualitative approach, this study examines the challenges, research methods, results, and conclusions of the company's employee selection practices. The findings point to the importance of minimizing risks in employee selection, including the identification of potential risks, the use of appropriate selection methods, and appropriate risk analysis tools. In conclusion, companies must focus on selection strategies that are in accordance with the company's culture and work environment, with an emphasis on developing employees who have abilities and motivation that are in line with industry demands.
Pelatihan Pengembangan Sistem Rekam Medis Elektronik Berbasis Web Di Klinik Prima Husada Bandung Untuk Mendukung Pelayanan Kesehatan Yang Berkesinambungan
Authors: Setiatin Sali , Syahidin Yuda , Novita Sari Pemi , Halimatusyadiah Sani , Indah Harini Sura , Septyani Juanda Yurika
Published: July 2024

The development of information technology in the health sector, especially a web-based electronic medical record (RME) system, is a strategic step to improve the efficiency and quality of health services in this digital era. This research aims to develop and implement a web-based RME system at the Prima Husada Clinic in Bandung as an effort to support sustainable and integrated health services. System development methods include needs analysis, comprehensive system design, measurable implementation, and evaluation of results. Implementation results show improvements in medical information accessibility, clinic operational efficiency, and coordination between medical teams. A discussion regarding the significant benefits of this implementation in the context of community health services was also discussed, while considering the challenges and solutions faced during the implementation process. This research emphasizes the importance of integrating information technology in improving health service standards in a sustainable manner.
Corporate Entrepreneurship Strategy Initiative at Gojek Indonesia
Authors: Nadhiva Meliniarta , Purnomo Margo , Purbasari Ratih
Published: July 2024

Corporate entrepreneurship becomes an innovation and creativity in solving problems and finding opportunities to improve business processes and enhance organizational performance. This study aims to explore successful corporate entrepreneurship initiatives at Gojek Indonesia to enhance competitiveness and provide added value to Gojek users and partners. This study uses a qualitative method with a literature review to identify, evaluate, and interpret all relevant sources. The results show that an innovative organizational culture, visionary leadership, and adequate resource availability support Corporate Entrepreneurship (CE) at Gojek. Gojek Indonesia has successfully implemented various innovative corporate entrepreneurship initiatives, such as developing GoPay and GoFood products, strategic partnerships with Tokopedia, and employee empowerment through training and development programs. The positive impact of corporate entrepreneurship at Gojek is evident in various aspects, including increased innovation and creativity, higher adaptability, operational efficiency, more comprehensive market penetration, increased customer loyalty and satisfaction, and long-term growth and sustainability. Therefore, corporate entrepreneurship is a critical element of modern business strategy that helps companies stay relevant and competitive and provide added value to users, partners, and the broader community
A Systematic Analysis of the Impact of the Military Conflict on the Distance Education System in Ukraine
Authors: Hruzevskyi Oleksandr
Published: July 2024

Distance learning has become one of the hottest educational trends of the 21st century. The COVID-19 pandemic and the war in Ukraine have only accelerated the process of its integration into the education sector. The purpose of this paper is to study the impact of distance education on adaptation to this teaching method and academic performance of students using it in both forms, as well as to find improvements that can be made to it. Methods included a systematic literature review using specific databases and inclusion/exclusion criteria. The databases used were Web of Science, Scopus, and Google Scholar. The results of the study showed that distance learning technologies, such as online laboratories, video lectures, interactive whiteboards, online educational platforms, chats, websites and other instant messaging tools, have become the only adequate response to the organisational challenges that have arisen in the new environment. The abrupt shift from traditional face-to-face learning to innovative forms of learning required a radical restructuring of educational institutions. This process also required students to adapt to new and unusual conditions. The paper outlines the negative aspects of distance education. It requires high self-discipline on the part of students, which can have a negative impact on their motivation and ability to create the necessary working environment. The lack of personal contact with an educational institution also leads to the loss of its cultural component. It has been found that distance education may be less effective in the absence of personal contact. However, blended learning, which combines traditional and distance methods, can address these challenges and unlock the potential of both forms of learning. This approach can compensate for the limitations of distance education, providing more effective learning and preparing students for future challenges in the globalised digital age.