bluuebunny/crossref_metadata_2025 huggingface dataset:
OVERVIEW OF METACOGNITIVE SKILLS ON NURSING STUDENTS
Authors: Hikmat Rohman , Yosep Iyus , Masala Clausewitz Welmatus , Nahdriah Nina
Published: January 2025

Background: Metacognitive skills play an important role in the academic success of Nursing students. However, understanding of the description of cognitive skills in nursing students is still limited, especially at Padjadjaran University. Efforts to evaluate and understand students' cognitive skill levels can provide valuable insights for the development of more effective Nursing education curricula. Objective: This study aims to describe the cognitive skills of Padjadjaran University Nursing students. Method: This research uses quantitative descriptive. The questionnaire used is the 18 item Self-Regulated Online Learning Questionnaire (SOL-Q) to measure students' cognitive skills. The sample technique uses accidental sampling. The sample in this study was 103 nursing students at Padjadjaran University. Data analysis uses univariate analysis. Results: The results of this study showed that 103 Nursing students at Padjadjaran University were research subjects. There were 61.3% of the total research subjects who had low metacognitive skills. These findings indicate the need for special attention to the development of cognitive skills, especially metacognitive skills, in the Nursing education curriculum. Potential factors influencing students' cognitive skills also need to be further explored. Conclusion: Understanding the description of cognitive skills in nursing students can be the basis for developing more effective and targeted learning strategies.
THE RELATIONSHIP BETWEEN PERSONAL HYGIENE PATTERNS AND DERMATITIS INCIDENTS AMONG HORTICULTURAL FARMERS IN SENDANGAGUNG
Authors: Theresia Avila Evi Kustanti  , Karunia Estri Arimbi , Ratnawati Emmelia
Published: January 2025

Background: Contact dermatitis is an inflammation of the skin caused by pesticides and chemical fertilizers that adhere to the skin. Personal hygiene is one of the indirect causes of contact dermatitis. Based on epidemiological data in Indonesia in 2017, 97% of 389 cases of skin diseases were contact dermatitis. Of these, 66.3% were irritant contact dermatitis and 33.7% were allergic contact dermatitis. In 2018, the national prevalence of dermatitis in Indonesia was 6.8%. Dermatitis ranked 17th at the Minggir Community Health Center for outpatient patients from January to February 2023. This research was conducted from June 25 to June 19, 2023. Objective: The purpose of this study was to determine the relationship between personal hygiene patterns and dermatitis among horticultural farmers in Sendangagung Village, Minggir Sub-district. Method: This quantitative research used an analytical observational study with a Cross-Sectional Study approach and employed Total Sampling with 61 samples. Instruments used included a questionnaire on personal hygiene patterns, a questionnaire on contact dermatitis, and observation of contact dermatitis. Results: Most respondents did not use personal protective equipment (PPE), amounting to 13 individuals (21.3%), and all horticultural farmers who used PPE did not use it properly, totaling 48 individuals (78.7%). Respondents with poor personal hygiene patterns were very few, totaling 8 individuals (13.1%). A small number of respondents experienced contact dermatitis, totaling 19 individuals (31.1%). Bivariate analysis using Fisher's exact test yielded a p-value of 0.001 (p-value < 0.05), indicating a significant relationship between personal hygiene patterns and the occurrence of dermatitis among horticultural farmers. Conclusions: There is a significant relationship between personal hygiene patterns and the occurrence of dermatitis among horticultural farmers in Sendangagung Village, Minggir Sub-district.
Carga exosomal: Biomarcadores en el diagnóstico del cáncer
Authors: Campoverde Ortega Gabriela , Proaño-Pérez Elizabeth
Published: January 2025

El cáncer es un problema de salud a nivel mundial, siendo una de sus principales problemáticas la detección a tiempo. Es por eso, que se ha propuesto la determinación de biomarcadores exosomales como posible herramienta al momento de diagnosticar esta patología, ya que, además de ser elementos importantes en la comunicación intracelular al transportar biomoléculas celulares como lípidos, ácidos nucleicos, proteínas y metabolitos asociados a su célula productora, actúan como principales reguladores del microambiente tumoral, encargado de la angiogénesis, progresión y desarrollo de metástasis. Para su aislamiento, existen diversas técnicas relacionadas con la ultracentrifugación, ultrafiltración e inmunoafinidad que permiten su separación de diferentes fuentes, ya sean, fluidos biológicos o medios de cultivo, facilitando su estudio en el contexto del cáncer.

Palabras clave: Exosomas; Biomarcadores de Tumor; Cáncer, Diagnóstico clínico.
Metals, sulfur content, and biochemical composition of macrocolonies of Nostoc sp. in different geographical locations in Ecuador
Authors: Morales Avendaño Ever , Correa-Abril Jhonny , Cabrera Elvia V. , Robles Carrillo Nilo M. , Arevalo Moreno Andrés Arevalo Moreno , Cadena Zumárraga Mabel
Published: January 2025

Nostoc sp. is a cyanobacterium identified in several localities of Ecuador, and it exhibits significant potential in the pharmaceutical, food, and environmental sectors, which urges the exploration of its possible applications in the country. Macrocolonies of Nostoc sp. were collected at different seasons, and the content of metals, sulfur, and biochemical composition was analyzed according to altitude and geographic position. The results showed that the average carbohydrate content corresponds to 30.34% dry biomass, 27.38% ash, 25.33% protein, 7.66% crude fiber, and 0.71% fat. Regarding the content of metals and elements, it was found that Aluminum presented the highest value of 2049.23 mg/kg, followed by 1786.74 mg/kg, 1364.08 mg/kg, and 443.12 mg/kg of Fe, Mg, and S, respectively, and with the lowest for Cu, Ni, Pb, and Cd of 7.34 mg/kg, 5.62 mg/kg, 3.99 mg/kg and 0.74 mg/kg; respectively; with the following descending order: Al>Fe>Mg>S>Cu>Ni>Pb>Cd at all sites sampled and regardless of altitude and period of rain or drought. Consequently, its potential to adsorb these elements from the environment is preliminarily demonstrated, showing that it could be used in applications for bioremediation of contaminated soils and waters or be an essential bioindicator of environmental pollution.
Keywords: Nostoc sp., biochemical composition, bioremediation, metals, sulfur
Mental conditions and eating disorders in patients in primary care, Ibarra, Ecuador
Authors: Barahona Meneses Amparito del Rosario , Hidrobo Guzman José Fabián , Pozo Benavides Andrea Jacqueline , Alvear Reascos Rodrigo Roberto , Acosta Vinueza Lola Yesenia
Published: January 2025

In Ecuador, thirty out of every hundred people suffer from a mental health problem, with depression being the most common, followed by anxiety. This study aimed to explore the relationship between eating disorders (EDs) and mental health conditions in patients seeking primary care for morbidity in Ibarra, Ecuador, between March and June 2023. A total of 1,707 subjects over 18 years of age participated in this study; 66% were women, and 34% were men. The "Global Mental Health Assessment Tool - Primary Care" questionnaire was used to identify mental health problems. A multivariate analysis was conducted to examine the association between the variables, and a binary logistic regression model was used to assess the risk factors for EDs. The results showed that 57.3% of the participants were young adults (20-39 years old), and 12.6% of the population had an ED. The most common mental health conditions were anxiety (38.7%), depression (34.9%), and stress (27.9%). EDs were statistically associated with sex, with women being more affected, and with age, with young adults (20-39 years old) being the most affected. In conclusion, depression, stress, and anxiety are determinants of EDs in this population, with depression showing the highest risk of incidence, followed by stress and anxiety.
Keywords: Eating disorders, mental disorders, adult, primary care
Perfil genómico del cáncer de cuello uterino en el diagnóstico de VPH
Authors: Ortega Becerra Andrea Nathalia , Valenzuela Sánchez Gabriela Paola
Published: January 2025

El cáncer de cuello uterino se presenta por anormalidad celular, generalmente ocasionada por la presencia del virus del papiloma humano (VPH), específicamente por genotipos de alto riesgo como VPH-16 y VPH-18. Sin embargo, existen subtipos de cáncer que no están asociados al virus y su desarrollo se origina por factores externos. La mayoría de genes y proteínas en el cáncer de cuello uterino están mutados o sobreexpresados por las oncoproteínas E6 y E7 del virus. No obstante, en cáncer de cuello uterino no asociados a VPH, estos marcadores se alteran como resultado de mutaciones o pérdidas de función de otros genes que actúan o influyen sobre los mismos o sobre las vías de señalización en las que participan. La implementación de estos biomarcadores podría facilitar el diagnóstico temprano y el tratamiento personalizado de los diferentes subtipos de cáncer de cuello uterino, centrándose en aquellos que no están asociados al virus del papiloma humano.

Palabras clave: cáncer de cuello uterino; HPV; genes; marcadores tumorales.
Analysis of Physiological Factors that Affect MAP (Mean Arterial Pressure) in Post Trepanation Patiens in Intensive Care Instalations
Authors: Sari Erlina Kartika
Published: January 2025

MAP (Mean Arterial Pressure) is the average arterial pressure required for blood circulation to the brain. In trepanation post op patients, MAP is an indicator of postoperative prognosis. This MAP is influenced by several physiological factors, namely heart rate, hematocrit and age. This study aims to determine and explain the effect of these three factors on MAP (Mean Arterial Pressure) in post-op trepanation patients at the Intensive Care Installation of Mardi Waluyo General Hospital, Blitar City. The design of this study is Cross-Sectional. Source of data used is secondary data. Data collection is done by observation method. The research sample was all medical records of trepanation post-op patients at the Intensive Care Installation of Mardi Waluyo Hospital, Blitar City who were treated from January to  December 2022 who met the inclusion criteria, totaling 42 respondents. Data analysis using binary regression with a significance degree of p value less than 0,05 (p<0.05). The results showed that the Nagelkerke R Square (Model Summary) value was 0.314. This shows that the contribution or influence of physiological factors (heart rate, hematocrit, age) on MAP is 31.4%, while the remaining 68.6% is determined by other variables that are not taken into account in this research model. It is suggested to health service providers, especially nurses, to further improve their ability to analyze critical values of patients to prevent worsening of the prognosis.
Mendepani Cabaran PBD: Analisis Hubungan Pengetahuan, Kemahiran, dan Sikap Guru
Authors: Ruslan Nor Aida
Published: January 2025

Kajian ini bertujuan untuk menganalisis hubungan antara pengetahuan, kemahiran, dan sikap guru matematik sekolah rendah di Batu Pahat terhadap pemberian Tahap Penguasaan (TP) dalam Pentaksiran Bilik Darjah (PBD). PBD, sebagai alat penilaian formatif, telah diperkenalkan dalam sistem pendidikan Malaysia untuk menilai perkembangan murid secara berterusan tanpa tekanan peperiksaan tradisional. Walaupun PBD membawa potensi yang besar dalam meningkatkan kualiti pendidikan, pelaksanaannya menghadapi beberapa cabaran. Kajian terdahulu mendapati bahawa kekeliruan terhadap kriteria penilaian TP, kurangnya kemahiran dalam pelaksanaan PBD, serta sikap negatif guru, seperti anggapan beban tambahan, telah menghalang keberkesanan pentaksiran ini. Kajian ini menggunakan pendekatan kuantitatif dengan kaedah soal selidik kepada sampel rawak berstrata guru-guru matematik sekolah rendah di Batu Pahat. Hasil kajian akan dianalisis menggunakan teknik statistik seperti analisis korelasi dan regresi berganda untuk menentukan kekuatan hubungan antara pengetahuan, kemahiran, dan sikap guru dalam pelaksanaan PBD. Dapatan kajian ini diharapkan dapat memberikan cadangan konkrit untuk meningkatkan tahap pemahaman dan kecekapan guru dalam melaksanakan PBD, seterusnya memperbaiki proses pembelajaran murid di Malaysia.
Dual impact analysis of GSTT1 polymorphisms on the metformin response and cardiovascular risk: A novel integrated approach in type 2 diabetes mellitus management
Authors: Dewi Ni Luh Made Noviana
Published: January 2025

Although genetic variations in glutathione S-transferase (GST) have been linked to type 2 diabetes mellitus (T2DM), the relationships among GSTT1 polymorphisms, metformin effectiveness, and cardiovascular risk remain unclear. This study investigated the association between the GSTT1 null genotype and the metformin monotherapy response while simultaneously assessing its impact on atherosclerotic cardiovascular disease risk. This case-control study examined 84 T2DM patients aged 30-70 years, categorized into metformin therapy responders and nonresponders. This study employed multiplex PCR for GSTT1 genotyping and utilized the pooled cohort equation for cardiovascular risk assessment, offering a comprehensive analysis of both genetic and clinical parameters. GSTT1 genetic variations were not significantly associated with metformin response (odds ratio [OR] 1.773, p=0.306) or cardiovascular risk (OR 1.086, 95% CI: 0.46-2.56, p=1.000). The analysis revealed distinct patterns in clinical parameters between the GSTT1 null and wild-type genotypes, particularly in terms of glycemic control indicators and lipid profiles, although these differences did not reach statistical significance. This study presents a novel approach by simultaneously examining both the therapeutic response and cardiovascular risk in relation to GSTT1 polymorphisms, distinguishing it from previous studies that typically focused on either aspect in isolation. These findings suggest that while genetic variations in GSTT1 may influence metabolic parameters, their direct impact on metformin effectiveness and cardiovascular risk may be more complex than previously thought.
Inovações em Saúde e Bem-Estar: Da Promoção da Saúde Mental à Tecnologia Avançada no Tratamento e Envelhecimento Saudável
Authors:   Editora Revista Dominio Cientifico, Nascimento Simoa da Silva Pamela , Skarabone Rodrigues Chiacchio Simon , de Carvalho Ribeiro Elidiane , Patrícia dos Santos Bezerra Aline , Maria lamego rezende Adriana , Wanne Alves Silva Sara , Vieira Cândido, Fabiano , Laiber Bonadiman Daniel , Cristina de Souza Oliveira Beraldo Luciana , Aryel Ribas Maurício Alex
Published: January 2025

Este e-book oferece um conjunto de temas que refletem as tendências contemporâneas e os desafios emergentes no campo da saúde, explorando soluções inovadoras e estratégias de impacto social. Os tópicos abordam desde as consequências da pandemia na saúde mental, como ansiedade, depressão e estresse pós-traumático, até o papel das comunidades na promoção da vacinação, especialmente em regiões subatendidas. O envelhecimento saudável é tratado com foco em programas de educação em saúde para a terceira idade, enquanto a nanomedicina e a robótica cirúrgica destacam tecnologias que moldam a medicina de alta precisão e impactam a economia.
A telemedicina e a inteligência artificial aparecem como pilares da saúde digital, ampliando o acesso ao diagnóstico e ao cuidado, enquanto questões éticas e socioeconômicas são cuidadosamente examinadas. Mindfulness e terapias complementares, assim como a realidade virtual na reabilitação, oferecem abordagens holísticas para o bem-estar, especialmente em contextos de trabalho e saúde mental dos jovens. O impacto das redes sociais e a adoção de wearables mostram como o autocuidado está sendo redefinido no contexto moderno.
Avanços como a impressão 3D em procedimentos médicos, a biotecnologia na prevenção de doenças e as políticas públicas de saúde preventiva destacam iniciativas que buscam personalização, sustentabilidade e equidade. Por fim, o futuro da medicina regenerativa, com o uso de células-tronco e engenharia tecidual, encerra a lista, representando o potencial transformador da ciência na regeneração de órgãos e na superação de limites médicos. Este conjunto de temas sintetiza uma visão ampla e integrada da evolução da saúde no século XXI.
Effect of Stand Density on Growth and Allometry of Marri (Corymbia Calophylla) in the High Rainfall Zone of Southwest Western Australia
Authors: Bhandari Shes K. , Veneklass Erik J. , McCaw Lachlan , Mazanec Richard , Renton Michael
Published: January 2025

Marri (Corymbia calophylla), an endemic and keystone tree species of southwest Western Australia (SWWA), provides significant environmental, conservation, economic and cultural values. This study aims to analyse the effect of stand density, manipulated through thinning, on growth and allometry of marri-dominated forest. Although individual tree diameter (DHBUB, diameter at breast height under bark), basal area, height and crown-width (CW) growth was stimulated by thinning, stand basal-area growth was highest in denser (less thinned) stands. Stand density had a significant effect on the allometry between DBHUB and each of height and height-diameter ratio (HDR). Height and CW increased with an increase in DBHUB although the relationship with CW was not statistically significant; HDR was inversely related to DBHUB. Thinning has the potential to increase yields of merchantable timber, firewood, and enhance ecological values including tree hollows for arboreal fauna and marri-fruit production (important for cockatoos) that depend on retention of sufficient large old trees. Reduction of stand density through thinning reduces inter-tree competition and may help in reducing the risk of marri canker disease.
A Critical Review of Survey Techniques and Perceived Threats for the Threatened Pilbara Ghost Bat (Macroderma Gigas)
Authors: Bradley Holly S. , Bullen Robert D. , Cross Sophie L. , Knuckley Chris G. , O'Connell Morgan , Ottewell Kym , Reiffer Scott , Wild Suzi , Van Leeuwen Stephen
Published: January 2025

Ghost bats of Western Australia’s Pilbara region are widespread, although patchily distributed, and are threatened with local extirpation, largely in part due to the expanding mining footprint across the region. The extensive data collected to inform environmental impact assessments for mineral exploration projects, however, provides a key source of information to inform ghost bat policy and management. At present, the effectiveness of this resource is limited by accessibility. To help bridge this gap, we conducted a comprehensive review of the grey literature on ghost bats, summarising strategies for survey techniques, perceived threats, and threat mitigation strategies. Numerous threatening processes were identified as impacting ghost bats, with habitat loss and the cumulative impacts of mining most reported. Survey techniques were found to often include a combination of indirect and direct methods, although the suitability of different techniques is reliant on the context of the study. For this reason, it is important for future environmental assessment reports to include a detailed method rationale to support better data comparability and population estimation across the Pilbara. Overall, comprehensive and comparable research outputs will help to better assess and understand extinction risks, and to develop effective conservation management plans for this threatened species.
Preliminary Appraisal of Biota From Methane-Seep and Associated Deposits, Lower Holmwood Shale, Early Permian (Sakmarian), Irwin Basin, Western Australia
Authors: Haig David W. , Dillinger Antoine , Playford Geoffrey , Riera Rosine , Sadekov Aleksey , Skrzypek Grzegorz , Håkansson Eckart , Mory Arthur J. , Peyrot Daniel , Thomas Charmaine
Published: January 2025

Fossil assemblages preserved in nodules of the methane-seep deposits, recognized by Haig et al. (2022) in the lower Permian (Cisuralian, Sakmarian stage) of the Irwin Basin, include representatives of three ecosystems: seep, pelagic, and coastal plain. The seep biota, new to the Australian Permian, consists of small thickets with a framework of tubeworms, less common algal-like Tubiphytes, and

problematica (? algae or sponges). Other components include microbial mats, macrophyte alga Litostroma (first report from Gondwana); foraminifers; sponges with siliceous monaxon spicules; a new group of small, lightly ornamented rostroconchs; microgastropods and rare larger types; ostracods and minute scolecodonts from polychaete jaws. Elements of the pelagic ecosystem are

ammonoids (abundant in enclosing shale) and marine microphytoplankton. Probable vertebrate bone (possibly amphibians) and diverse spores and pollen from land plants come from the adjoining coastal plain. The surrounding mudstone lacks benthic macrofauna but includes an unusual assemblage of siliceous agglutinated foraminifers. The seeps were oases of high organic

productivity on an otherwise barren muddy seafloor. The Holmwood Shale’s seep carbonates have close similarities to modern seep deposits in shallow-marine settings.
Long-Term Evaluation of Transanal Pull-Through For Hirschsprung Disease: A Prospective Study of 18 Cases from Senegal
Authors:   Chirurgie pediatrique, Universite Cheikh Anta Diop de Dakar (UCAD), Hôpital d’enfants Albert Royer de Dakar, Senegal, Ndoye Ndeye Aby , Lo Faty Balla ,   Chirurgie pediatrique, Hôpital National Pikine, Dakar Senegal, Seye Cheikh ,   Chirurgie pediatrique, Diourbel Regional Hospital Center Heinrich Lübke (CHRHL de Diourbel), Université Alioune Diop, Senegal, Cisse Lissoune ,   Chirurgie pediatrique, Hôpital National Pikine, Dakar Senegal, Welle Ibrahima Bocar ,   Chirurgie pediatrique, Universite Cheikh Anta Diop de Dakar (UCAD), Hôpital d’enfants Albert Royer de Dakar, Senegal, Diehdiou Youssouph ,   Chirurgie pediatrique, Universite Cheikh Anta Diop de Dakar (UCAD), Hôpital d’enfants Albert Royer de Dakar, Senegal, Ndour Oumar ,   Chirurgie Pediatrique, Hôpital Aristide Le Dantec (HALD), Dakar, Senegal, Ngom Gabriel ,   Chirurgie pediatrique, Universite Cheikh Anta Diop de Dakar (UCAD), Hôpital d’enfants Albert Royer de Dakar, Senegal
Published: January 2025

Introduction: Distal colonic aganglionosis is increasingly been treated with transanal pull-through that avoids a laparotomy. This study is intended to evaluate the results of this approach in a resource-limited setting.
Methods: This is a descriptive study done prospectively between 2016 and 2023 at the Albert Royer Children's Hospital, Dakar, Senegal. It includes 18 children operated upon exclusively by De la Torre-Mondragon’s technique of transanal pull-through for Hirschsprung disease. Morbidity and anal continence were evaluated using the simplified Holschneider and Krickenbeck scores.
Results: The mean follow-up duration was 6 yr (range 4-7 yr). Immediate complications were diaper rash and anal fissures. According to the Holschneider scoring system continence was normal in 11 patients (61%), good in 5 (28%), and satisfactory in 2 (11%). However, occasional soiling was noted in 56%. According to the Krickenbeck score, continence was noted in 16 patients (89%), while 10 patients (56%) suffered from fecal incontinence and 4 patients (22%) from constipation. Three patients (17%) reported restricted social life as a direct consequence of impaired bowel function.
Conclusion: Transanal colonic pull-through may lead to long-term morbidity, such as soiling, which can significantly affect the quality of life.
Burns in Children: Epidemiological, Clinical, Therapeutic and Outcome Aspects at the Albert Royer Children's Hospital in Dakar
Authors:   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal, Ndoye Ndèye Aby ,   Faculty of Medicine, Pharmacy, Odontology and Stomatology, Université Cheikh Anta Diop, Dakar, Senegal, Zeng Florent Tshibwid A ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal, Diedhiou Youssouph ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal, Ondzanga Guy-Aimé Magnifique ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal, Agne Abibatou El Fecky ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal, Sagna Aloïse ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal,   Faculty of Medicine, Pharmacy, Odontology and Stomatology, Université Cheikh Anta Diop, Dakar, Senegal, Mbaye Papa Alassane ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal,   Faculty of Medicine, Pharmacy, Odontology and Stomatology, Université Cheikh Anta Diop, Dakar, Senegal, Wellé Ibrahima Bocar ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal, Ngom Gabriel ,   Department of Pediatric Surgery, Albert Royer National Children’s Hospital Center, Dakar, Senegal,   Faculty of Medicine, Pharmacy, Odontology and Stomatology, Université Cheikh Anta Diop, Dakar, Senegal
Published: January 2025

Introduction: Childhood burns are common injuries that carry significant morbidity. In this article, the outcome of pediatric burns in Senegal is audited.
Methods: This is a retrospective, descriptive study carried out over 20 months, from May 1, 2021, to December 31, 2022, at the pediatric surgery department of the Albert Royer Children's Hospital in Dakar. Demographic and clinical parameters were studied.
Results: During the study period 78 skin burns were treated as in-patients. This formed 10.02% of all hospital admissions during that period. The mean age was 43 months (range 6mo - 15yr). The sex ratio was 1.16. Burns occurred in the morning in 38% of cases. The mean delay of medical consultation was 72 hr. Spillage of hot liquid was the commonest etiology in 85% of cases. Transportation had been done by non-medical vehicles in 95% of cases. The mean extent of burns was 11% of total body surface area. All of them were second degree burns. Multiple body parts were burnt in 83% of patients. The mean length of hospitalization was 9 days. Anemia was found in 29.5% of children. The mortality rate was 6.4%.
Conclusion: Skin burns are common in Senegalese children, and are most often due to domestic accidents. In our resource-limited setting, the morbidity and mortality remains high. Preventive measures appear to be the practical way of reducing them.
REVIEW OF PHARMACOLOGICAL INTERVENTIONS FOR THE PREVENTION OF HEALTHCARE-ASSOCIATED INFECTIONS 2025
Authors: Khan Majida , Jamal Muhammad , Bangash Sudhair Abbas , Ejaz Aleem , Mahmood Waqas , Afzal Fatima , Ali Ahmad
Published: January 2025

Healthcare-associated infections (HAIs) are a significant threat to patient safety, contributing to increased morbidity, mortality, and healthcare costs globally. Pharmacological interventions are pivotal in preventing HAIs and addressing antimicrobial resistance.
Objective: This narrative review explores key pharmacological strategies for preventing HAIs, including prophylactic antibiotics, antimicrobial stewardship programs (ASPs), infection prevention bundles, and innovative approaches like probiotic cleaning systems.
Methods: The review synthesizes recent literature on established and emerging HAI prevention strategies, evaluating their efficacy, challenges, and applicability across diverse healthcare settings.
Results: Prophylactic antibiotics are highly effective in reducing surgical site infections when used judiciously, while ASPs optimize antibiotic use and combat resistance. Infection prevention bundles, incorporating evidence-based practices like hand hygiene and catheter care, significantly lower bloodstream infection rates. Innovative approaches, such as probiotic cleaning systems, offer sustainable solutions to reduce environmental contamination. However, challenges remain, including variable adherence to protocols, resource constraints, and the need for scalable solutions in low-resource settings.
Conclusion: Pharmacological interventions, when integrated with multidisciplinary approaches, are crucial for reducing HAI rates and improving patient outcomes. Future research should focus on scalable innovations and context-specific strategies to enhance infection prevention globally.
Keywords: Healthcare-associated infections, Antimicrobial stewardship, Prophylactic antibiotics, Infection prevention bundles, Multidrug resistance, Patient safety.
Dexmedetomidine as an Adjunctive Sedative in Patients Undergoing Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis
Authors: Abosheaishaa Hazem , Abdallfatah Abdallfatah , Abdelghany Abdelmalek , Sethi Arshia , Ismail Abdellatif , Mohamed Doha , Aboeldahb Moataz , Abdelhalim Omar , Mohamed Islam , Azzam Ahmed Y. , Nassar Mahmoud , Bilal Mohammad
Published: January 2025

Introduction: Endoscopic submucosal dissection (ESD) is a technique for removing dysplastic lesions in the gastrointestinal tract but carries risks like pain and perforation. Dexmedetomidine, an α2-receptor agonist, offers potential benefits as an adjunct sedative during ESD by providing anxiolysis and analgesia. This systematic review and meta-analysis assesses its efficacy and safety.
Methodology: We searched databases including Embase, Medline/PubMed, Scopus, and Web of Science up to April 21, 2024, following PRISMA guidelines. Eligible studies used dexmedetomidine with other sedatives for ESD. We analyzed outcomes such as en-bloc and complete resection rates, sedation duration, and adverse events, using RevMan for meta-analysis with a random-effects model.
Results: The initial search retrieved 216 studies and after screening, eight studies were included in the final analysis. Dexmedetomidine showed no significant difference in en-bloc or complete resection rates compared to controls. Sedation and procedure times were similar between the two groups as well. Dexmedetomidine significantly reduced restlessness (OR 0.15, 95% CI:0.07 to 0.29) and increased bradycardia (OR 7.15, 95% CI 3.17 to 16.11) compared to controls. Upon subgroup analysis, Dexmedetomidine plus Propofol, and Dexmedetomidine plus Midazolam, revealed the same findings regarding restlessness and bradycardia compared to controls which confirmed the adjunctive effects of Dexmedetomidine.
Conclusion: Dexmedetomidine as an adjunctive sedative appears safe and effective in ESD, reducing restlessness without significant adverse events. The risk of bradycardia is increased, which may be reflective of reduced physiological stress. Future studies should explore optimal dosing and compare Dexmedetomidine with other sedatives in diverse populations.
An-tooo-nius!
Authors: Sørensen Viggo
Published: January 2025

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Statistical accounting of religious groups: some data on the history of Old Believer statistics in the Olonets and Arkhangelsk provinces
Authors: Kuznetsova Natalya Yurevna
Published: January 2025

The article examines the features of the statistics of accounting for religious groups in the Russian Empire on the example of the Old Believer community in the Olonets and Arkhangelsk provinces in the XIX century. A brief digression is made into the history of the formation of statistics in Russia within the framework of the XIX century. This allows you to see on what data the registration of believers took place, as well as who and how it was conducted. Within the framework of the study, special cases of statistical accounting of Old Believers in the Olonets and Arkhangelsk provinces are considered, demonstrating the difficulties encountered in this matter. In particular, statistical tables are provided for a number of counties, which show discrepancies in the data. Such discrepancies became possible due to the difference in approaches to accounting for Old Believers among officials, the police and the clergy.   The research is based on the analysis of archival data from the National Archive of the Republic of Karelia and the State Archive of the Arkhangelsk region. Materials from the funds of the provincial statistical committees are compared and compared. The author comes to the conclusion that despite all the standardization of state statistics and the importance of the issue of accounting for religious groups of the population, the statistics of the Old Believers in the northern provinces had a number of difficulties. They concerned both the field accounting itself and the data consolidation into single tables. In particular, the question of who more accurately counted representatives of other religious groups that do not belong to official Orthodoxy remained open. The statistical tables provide data from both the police and the priests of local parishes. They are often very different. Another point that the author comes to in the study is the importance of comparing data over several years and the moment they are reflected in statistics. The research was carried out at the expense of a grant from the Russian Science Foundation No. 23-28-10260, https://rscf.ru/project/23-28-10260 / conducted jointly with the Republic of Karelia with financing from the Venture Capital Investment Fund of the Republic of Karelia (FVI RK).
“Cualquier movimiento revolucionario podrá contar con Cuba”: la construcción del nacionalismo internacionalista cubano durante el Año de la Solidaridad (1966)
Authors: García Molinero Alberto
Published: January 2025

Objective/context: This article deepens the conceptualization of the historical phenomenon called "Cuban internationalist nationalism," framed in the so-called Year of Solidarity (1966) and inaugurated with the Tricontinental Conference held in Havana during the height of the Cold War. Metodologia: We propose an interdisciplinary analytical approach, which combines the study of the history of daily life and oral history, embodied in various testimonies, with unpublished documentary sources. Originality: The singularity of this text lies in the conceptual hypothesis manifested in the notion of "internationalist nationalism," constituted at the time of the extended 1960s. The novelty of such a historical look grants a marked ground-breaking character to the present article: the notion is rescued and analyzed from hitherto unknown voices coming from diverse spheres of Cuban society and partially explored repositories, such as Archivo Histórico del Instituto Cubano de Amistad con los Pueblos or Archivo Histórico de la Organización de Solidaridad de los Pueblos de África, Asia y América Latina, known (by its Spanish acronym) as the ospaaal. Conclusions: The article confirms the existence of a marked international projection within the Cuban national sentiment. This internationalist nationalism had a strong imprint on the configuration of the revolutionary identity from its origins to our times, as revealed by the accounts of personalities imbued within this reality. In the framework of the most immediate present, despite the significant global geopolitical transformations that have taken place since the end of the Cold War, this international spectrum continues to be a central pillar in contemporary Cuban society in the face of the multiple challenges it faces in the 21st century.
Nacionalismo militarista cotidiano en las escuelas de la dictadura chilena: usos rituales de los actos cívicos y las efemérides (1973-1980)
Authors: Neut Aguayo Sebastián , Neut Aguayo Pablo
Published: January 2025

Objective/context:This article analyzes how the Chilean dictatorship tried to instill a militaristic nationalism in the country’s school’s daily life, showing how this nationalism was reappropriated and, in some cases, resisted by part of the student body and the teaching staff. This approach is based on the study of civic events and the commemoration of school anniversaries between 1973 and 1980. Methodology: We proceed to the triangulation between different primary materials, specifically, the magazine Revista de Educación of the Ministry of Education, declassified documents referring to internal communications of the dictatorship on educational matters (as well as on the repression in this field), materials from the academic archives of the Instituto Nacional and the Liceo Javiera Carrera, judicial records and interviews with teachers and students of the time. Originality:The crossing of the theories of nationalism and daily school life is used, and it is found that the dictatorship produced a new grammar of educationalization that profoundly impacted the school culture. This was characterized by the display of a profound military-nationalist ritualization. Unlike other studies on the period, attention is paid to the ideological use and daily expression of school rituals and the transgressions carried out in the ritual dimension. Conclusions: The attempt to implant a military-nationalist vision through daily school rituals was relatively successful since, while part of the students naturalized the existence of such military-nationalism, another part opposed it through the transgression/resistance of the very rituality that promoted it. This last shows the existence of a conflictive dimension of school culture.
Hilda Sabato: itinerarios, horizontes y problemas para la historia política
Authors: Sabato Hilda , Garrido Margarita , Hensel Franz , Ortega Francisco A
Published: January 2025

Hilda Sabato is a referent of Hispano-American historiography. As a result of the launching of the first volume of the editorial project Historias de lo político en Colombia: imaginando repúblicas en tiempos de independencia, 1780-1852 (Bogotá: Universidad Nacional de Colombia; Universidad del Rosario, 2024), we took advantage of Hilda Sabato's presence in Bogotá to talk with her about the familial, political and intellectual context of her formative years, her experience amid the dictatorships in the Southern Cone, her return to Argentina in the late 1970s and the process of democratic and institutional reconstruction, particularly in the university sphere. We also talked about her concerns and theoretical approaches in the political sphere, as well as her view of the configuration of the republic after the monarchical fracture and the construction of political communities throughout the nineteenth century. In short, the interview addresses the problems and questions that Sabato has sought to resolve through her extensive bibliography.
Lugares amados, lugares sombra: éticas y estéticas en tiempos de transición
Authors: Roa García María Cecilia , Quecedo del Val Alejandro , Lagrève Nils , Amaya Morales Ana Manuela
Published: January 2025

Cañaverales, a community in southern La Guajira (Colombia), is at risk of becoming a shadow place, much like other villages that have vanished due to open-pit coal mining. These towns, disconnected from the national energy grid, have maintained close relationships with natural energy sources—such as the sun, wind, water, and food—despite the lifestyle changes brought by the use of fossil fuels. These connections, however, are steadily eroded by the encroachment of modernity. The disappearance of these traditional energy practices is a profound paradox: at a moment when the urgency to cease burning fossil fuels is clearer than ever, coal mining erases age-old energy practices that have thrived in simplicity, small scale, and ethical harmony with the land. This article explores this paradox through the lens of beloved places and shadow places. Cañaverales represents thousands of communities across the Global South that have sustained relationships of care, awe, reciprocity, and attunement with their territories—what we call beloved places. These communities resist being reduced to mere suppliers of renewable or fossil energy for distant regions, becoming instead shadow places. The extraction of coal from Cañaverales symbolizes the erasure and forced disappearance of these deep-rooted relationships with energy, transforming their ethics and aesthetics into memory and haunting specters of what once was.
Entre sacrificios y esperanzas: análisis de conflictos socioambientales en Bogotá desde una perspectiva de ecología política
Authors: Nova Laverde Mariluz , Piñeros Fuentes Milton , Rojas Mora Jaime Edison
Published: January 2025

This article examines socio-environmental conflicts through the lens of political ecology, focusing on the disconnection within the society-nature dialectic and the dualistic, hierarchical understanding of urban-rural dynamics. The study is set in Bogotá, specifically in the Pasquillita village, a territory affected by the Doña Juana landfill and urban expansion. Two research strategies are used: first, an analysis of the historical and material injustices shaping these territories, using a socio-environmental justice index to highlight the inequalities that form sacrifice geographies; and second, the documentation and systematization of local experiences, knowledge, and practices arising from processes of self-recognition and peasant resilience to identify the creation of geographies of hope. The socio-environmental justice index reveals significant disparities in the distribution of socio-economic and ecological conditions between rural and urban areas, while the documentation of experiences showcases innovative strategies of collective action by diverse communities with hybrid identities, who propose alternative ways of living and being rooted in the recovery of ancestral knowledge and peasant traditions. This is illustrated through work with the Asopasquillita peasant association, which is committed to healing and caring for the land. From this emerges the concept of wise territories as part of an ecology of knowledge, serving as a guiding principle for socio-environmental justice. This research contributes to critical geography, rural studies, and environmental justice by incorporating relational ontologies and a decolonial and ecofeminist perspective.
¿Podemos escuchar a la naturaleza? La naturaleza como víctima y testigo en el Informe final de la Comisión de la Verdad en Colombia
Authors: Villegas Andrés , Castrillón Gallego Catalina
Published: January 2025

Drawing on the premises of the ontological turn, this article explores the recognition of nature as both a victim and a witness to the Colombian armed conflict, as framed by the Commission for the Clarification of Truth, Coexistence, and Non- Repetition. The analysis is based on an in-depth review of the report When the Birds Did Not Sing, supplemented by an examination of other volumes of the Truth Commission’s Final Report and its extensive supplementary materials. It also incorporates transcripts of numerous testimonies collected by the Commission and rulings from other institutions that recognize nature or territory as subjects of rights and as victims. The findings reveal that the Commission adopted no singular understanding of nature. Among the multiple interpretations it offers, the most compelling considers nature as a witness to the harm inflicted upon it. This perspective is rooted in (i) the relational ontologies of campesino, Indigenous, and Afro-Colombian communities who testified; (ii) the political dimension of these ontologies, which positions harm and reparation as contested and negotiable within worlds that are “more than one and less than many”; and (iii) the notion that nature itself testifies, as the production and interpretation of signs is an inherent property of life. Ultimately, the article argues that the Commission shifts the question from “Can nature speak?” to “Can we listen to it?”
A influência da qualificação docente no desempenho acadêmico em cursos de engenharia de produção: análise comparativa regional no Brasil
Authors: Souza Érika Márcia Assis de , Machado Priscila Alves da Silva , Santos Liliane Cruz Gomes de Souza , Lima Tadeu Henrique de , Rodrigues Joice Martinha , Diniz Hélio Augusto Goulart
Published: January 2025

O crescimento expressivo de cursos de Engenharia de Produção no Brasil, com um aumento superior a 300% nos últimos sete anos, contrasta com o desempenho insatisfatório de 42% dos cursos no Enade, classificados com notas 1 ou 2 no ciclo avaliativo mais recente. Este estudo investiga a influência da qualificação docente, em termos da proporção de mestres e doutores, nas notas do Enade, comparando duas macrorregiões: grupo A (Norte, Nordeste e Centro-Oeste) e grupo B (Sul e Sudeste). Adotando uma abordagem quantitativa com análise estatística dos dados, os resultados revelam que a presença de mestres não possui impacto significativo no desempenho dos cursos, enquanto a proporção de doutores se mostrou positivamente correlacionada às notas do Enade em ambas as regiões. Esses achados destacam a relevância de políticas educacionais voltadas ao aumento do número de doutores nos cursos de Engenharia de Produção, contribuindo para a melhoria da qualidade do ensino e do desempenho acadêmico. Conclui-se que a qualificação docente exerce papel determinante na avaliação institucional, especialmente em contextos regionais desiguais.
Uso de substâncias psicoativas em atletas: uma análise jurídica do uso de Smart Drugs para potencializar o desemprenho
Authors: Alves Fabrício Germano , Castro Júllia Andrade de
Published: January 2025

O presente artigo explora o uso de smart drugs, também conhecidas como nootrópicos, no contexto do aprimoramento humano no esporte, com foco nos efeitos, benefícios, riscos à saúde e nas implicações legais dessa prática. A crescente utilização dessas substâncias, especialmente em ambientes acadêmico, profissional e esportivo, tem gerado debates intensos sobre sua eficácia, potenciais danos à saúde dos usuários e o papel das regulamentações governamentais no controle e regulamentação dessas substâncias. A metodologia adotada é de abordagem qualitativa, utilizando o método hipotético-dedutivo, e contempla análise de doutrina, artigos acadêmicos, legislações nacionais e resoluções, por meio de pesquisa bibliográfica. Conclui-se que o uso das principais smart drugs para melhorar o desempenho esportivo é ilegal quando usado para fins não terapêuticos, representa sérios riscos à saúde e compromete a integridade das competições.