bluuebunny/crossref_metadata_2025 huggingface dataset:
Noncoding RNAs and Intracerebral Hemorrhage
Authors: Li Lingzhi , Wang Pingping , Zhao Haiping , Luo Yumin
Published: February 2019

Background & Objective:

Intracerebral hemorrhage (ICH) is the most devastating subtype of stroke, for which there are few effective interventions. Computed tomography is accepted as the gold standard for diagnosis, whereas surgical evacuation is the main treatment for ICH. However, in emergency rooms, time is limited and information regarding a patient’s clinical status or tolerance is typically not available. Many studies over the last decade have investigated the fundamental mechanisms of ICH and especially hematoma, which not only cause physical damage but also release toxins that have detrimental effects. However, there remain many gaps in our understanding of ICH. Compared to ischemic stroke, there is little known about the ICH pathogenesis and treatment options, and few specific biomarkers are available for monitoring disease progression, which include hematoma enlargement and perihematoma edema. Noncoding RNAs (ncRNAs) are involved in various biological processes and are potential biomarkers and therapeutic tools in central nervous system diseases. Recent studies have examined the role of ncRNAs including microRNAs, long noncoding RNAs, and circular RNAs—the three main subgroups associated with stroke—in ICH models. A deeper understanding of the functions of ncRNAs in different biological processes can provide a basis for developing more effective therapeutic strategies to prevent neuronal damage following ICH. In clinical settings, ncRNAs can serve as biomarkers for predicting the degree of injury resulting from ICH.

Conclusion:

In this review, we discuss the current state of knowledge of the role of ncRNAs in ICH.
Exploring the Patent Landscape of RNAi-based Innovation for Plant Breeding
Authors: Frisio Dario Gianfranco , Ventura Vera
Published: February 2019

Background:

RNA interference (RNAi) is an innovative technique for plant improvement
based on naturally occurring mechanisms which show great potential because of their high
specificity and possibility to be applied through innovative methods of topical application in
plants. This specific innovation sector is worth analysing from the economic perspective given the
great potentiality of RNAi-based plants and products to support modern agriculture in reaching the
goals for the improvement of agri-food chains global sustainability. This paper aims to evaluate
the global landscape of RNAi innovation by analysing patent data as indicators of innovation output.

Methods:

We revised all patents relating to RNAi in plants based on a dataset of roughly seven
thousand patent families. The analysis classified inventions according to a set of variables able to
characterise the dynamics of innovation (i.e. public/private ownership, type of plants involved,
main traits) while the use of concentration indices provided insights into the evolution of this sector.

Results:

Results revealed that RNAi is a technique with promising future applications, able to
provide solutions to a great variety of agricultural issues and principally developed by the US and
Chinese applicants, whereas European innovation capacity in this field appears to be limited.

Conclusion:

The innovation landscape of plant breeding is rapidly evolving and RNAi technique
is probably going to play a major role in this field.
Core Data Elements in Acute Myeloid Leukemia: A Unified Medical Language System–Based Semantic Analysis and Experts’ Review (Preprint)
Authors: Holz Christian , Kessler Torsten , Dugas Martin , Varghese Julian
Published: February 2019

BACKGROUND

For cancer domains such as acute myeloid leukemia (AML), a large set of data elements is obtained from different institutions with heterogeneous data definitions within one patient course. The lack of clinical data harmonization impedes cross-institutional electronic data exchange and future meta-analyses.

OBJECTIVE

This study aimed to identify and harmonize a semantic core of common data elements (CDEs) in clinical routine and research documentation, based on a systematic metadata analysis of existing documentation models.

METHODS

Lists of relevant data items were collected and reviewed by hematologists from two university hospitals regarding routine documentation and several case report forms of clinical trials for AML. In addition, existing registries and international recommendations were included. Data items were coded to medical concepts via the Unified Medical Language System (UMLS) by a physician and reviewed by another physician. On the basis of the coded concepts, the data sources were analyzed for concept overlaps and identification of most frequent concepts. The most frequent concepts were then implemented as data elements in the standardized format of the Operational Data Model by the Clinical Data Interchange Standards Consortium.

RESULTS

A total of 3265 medical concepts were identified, of which 1414 were unique. Among the 1414 unique medical concepts, the 50 most frequent ones cover 26.98% of all concept occurrences within the collected AML documentation. The top 100 concepts represent 39.48% of all concepts’ occurrences. Implementation of CDEs is available on a European research infrastructure and can be downloaded in different formats for reuse in different electronic data capture systems.

CONCLUSIONS

Information management is a complex process for research-intense disease entities as AML that is associated with a large set of lab-based diagnostics and different treatment options. Our systematic UMLS-based analysis revealed the existence of a core data set and an exemplary reusable implementation for harmonized data capture is available on an established metadata repository.
Identifying key steps in developing a one-stop shop for health policy and system information in a limited-resource setting: A case study. (Preprint)
Authors: Mutatina Boniface , Basaza Robert , Sewankambo Nelson K , Lavis John N
Published: February 2019

BACKGROUND

There is limited understanding about the development and implementation of the one-stop shops for evidence in a limited-resource setting such as Uganda. Previous efforts to develop one-stop shops have focused on global research evidence and local policy-relevant documents to address questions about health interventions and health systems in high-income countries.

OBJECTIVE

This study aimed to identify key steps in the development of on-line evidence-based information resources for health policy and system for a limited-resource setting.

METHODS

We utilised a case study design to address our objective where the case (i.e. unit of analysis) was defined as “the development process of the Uganda Clearinghouse for Health Policy and System”. We collected data from multiples sources including key informant interviews, participant observations and archival records to develop a comprehensive account for the case under investigation.

RESULTS

We found out that the development of the Uganda Clearinghouse for Health Policy and System followed a seven-step process, characterized by iterations that occurred within and between the steps. The essential components of the process included developing the concept; prototyping of the key structure; engaging with policy makers, researchers and other stakeholders; conducting a scoping review of policy relevant documents to identify and index the content; dissemination of the resource; user-testing; and updating of the system.

CONCLUSIONS

Our study provides key steps for developing a one-stop shop for local evidence to inform health policy and system decisions in a limited resource setting. Researchers, especially those in similar settings may apply this step by step inventory to develop similar resources.

CLINICALTRIAL

N/A
Monitoring of Pollution of Salmonella sp. in Raw Milk Using Virulence Gen Marker
Authors: Liwan Stefanie Yolanda , Budiarso Tri Yahya
Published: February 2019

Salmonella sp. is an enteropathogenic organism and it can spread through contaminated food which is rich in nutrition such as raw milk. The goal from this research is to find out the suitable pasteurization and time effect on the growth isolates Salmonella sp. that its invA presence is detected. Seventy-five (75) samples were taken in three locations of milk collection from groups of breeders. 10 ml of milk samples were grown in enrichment culture of modified Tryptic Soy Broth (mTSB) at 37oC for 12 hours. Cellular culture was then grown in differential selective medium of Salmonella Shigella Agar (SSA) and Chromocult Coliform Agar (CCA). From 75 milk samples produced 1392 colonies of typical Salmonella sp. pathogens. Then, isolates were selected using Triple Sugar Iron Agar (TSIA) and Urea Broth media, producing 3 suspected isolates of Salmonella sp which was known from colonies color. Results of confirmation using API 20E and 50 CHE produced two isolates of Salmonella spp. with %ID = 99.6% and one isolate of Salmonella typhi with %ID = 72.1%. All of the isolates were then detected for virulence factor using invA marker and all positive isolates have virulence factor. It indicates that raw milk contains polluted pathogenic bacteria.Keywords: raw milk, enteric pathogenic, virulence gen
Cased Based Reasoning to Identify Cause Conflicts in Marriage
Authors: Ichwani Arief , Suprapto Suprapto
Published: February 2019

The function of KUA in the activities surrounding the religion of Islam, including providing service and guidance in the area of present services in terms of marriage and reconcilement for Muslims, provide services and guidance in the field of development of Sakina, family consultation conflict or household problems, and so on. Integration between the computer and artificial intelligence into the post-wedding consulting services is one approach in overcoming the limitations of the expert (religious instructor).This research aims to identify conflict in marriage by applying Naive Bayes algorithm at the stage of determining the groups of test data (retrieve), then entered the stage of the search process of the highest similarity value by using the Nearest Neighbor algorithm (reuse). The data source and the test data used are divided into two groups, namely marriage, and history data consultation, While the group conflicts are identified will be divided into five classes, namely an employment factor, the factor of age, educational factors, factors the number of weddings, and social status.Testing is performed by the use of 12 data, consisting of 11 data cases and 1 test data. At the stage of determination of group conflict acquired test data included in group one i.e. F001 (factor of the job), so at the stage of looking for value similarities used only the base case of the class F001 i.e. KK001, KK003, and KK008. The KK001 similarity has a value of 0476, KK003 of 0882, and KK008 of 0142. The case with most high similarity value will be stored as a base case. If the value similarity obtained less than the threshold value that is 0.8, then the solution of the case will be revised by experts. The results of the calculation accuracy, using 35 new test data that gets the value of 82.86%.
Hate Speech Detection for Indonesia Tweets Using Word Embedding And Gated Recurrent Unit
Authors: Patihullah Junanda , Winarko Edi
Published: February 2019

Social media has changed the people mindset to express thoughts and moods. As the activity of social media users increases, it does not rule out the possibility of crimes of spreading hate speech can spread quickly and widely. So that it is not possible to detect hate speech manually. GRU is one of the deep learning methods that has the ability to learn information relations from the previous time to the present time. In this research feature extraction used is word2vec, because it has the ability to learn semantics between words. In this research the GRU performance will be compared with other supervision methods such as support vector machine, naive bayes, decision tree and logistic regression. The results obtained show that the best accuracy is 92.96% by the GRU model with word2vec feature extraction. The use of word2vec in the comparison supervision method is not good enough from tf and tf-idf.
Levels of Political Participation Based on Naive Bayes Classifier
Authors: Hidayatillah Rumaisah , Mirwan Mirwan , Hakam Mohammad , Nugroho Aryo
Published: February 2019

Nowadays, social media is growing rapidly and globally until it finally became an important part of society. During campaign period for the regional head election in Indonesia, the candidates and their supporting parties actively use social media as a campaign tool. Social media like Twitter has been known as a political microblogging media that can provide data about current political event based on users’ tweets. By using Twitter as a data source, this study analyzes public participation during campaign period for 2018 Central Java regional head election. The purpose is to observe how much reaction is given to each candidate who advanced in the election. By using the crawling program, all tweets containing certain candidate names will be downloaded. After going through a series of preprocessing stages, data can be classified using Naive Bayes. Predictor features in classification datasets are the number of replies, retweets, and likes. While the target variable is reaction that is divided into three levels, including high, medium, and low. These levels are determined based on users’ reaction in a tweet. By using these rules, Naive Bayes managed to classify data correctly as much as 76.74% for Ganjar Pranowo and 68.81% for Sudirman Said.
Book Review: Islamic Political Discourse in the Reform Era
Authors: Manalu Dimpos
Published: February 2019

The connection between the state and Islam is a dynamic and important theme inIndonesian political discourse, a situation inseparable from some Muslims' aspirationsfor Islam to become the ideology (foundation) of the state. In the important politicalevents that have occurred, such polemics have often emerged and become sources ofserious political tensions.Carool Kersten's book, an Indonesian-language translation of Islam inIndonesia: The Contest for Society, Ideas, and Values (2015), examines thecontestations of discourses and actors during Indonesia's Reform Era within therelationship of the state and religion (Islam). This book comprehensively explains how two groups—progressive Muslims and conservative (reactionary) Muslims—havecontinued their predecessors' struggles. It focuses specifically on the first group, as wellas the diverse sub-discourses included therein.
O estado do conhecimento sobre estágio supervisionado nas licenciaturas
Authors: Gabriel Fábio Antonio , Pereira Ana Lúcia , De Jesuz Danilo Augusto Ferreira
Published: February 2019

O Estágio Supervisionado compõe uma das etapas na formação inicial do professor, como um momento único e importante, uma vez que enseja ao futuro professor o contato com a realidade escolar a fim de que o estagiário, futuro professor, perceba como serão suas atividades como docente. O presente artigo, portanto, tem como objetivo realizar um levantamento do estado do conhecimento sobre Estágio Supervisionado nos cursos de licenciaturas.  A metodologia da pesquisa utilizada foi a pesquisa bibliográfica e do tipo estado do conhecimento. Os resultados permitem apontar que o Estágio Supervisionado é o momento oportuno do acadêmico assimilar saberes da experiência para, paulatinamente, construir sua identidade profissional e, desse modo, poder ter condições de ser um bom professor quando chegar seu momento de atuar profissionalmente.
Ensino de História e pensamento decolonial em processos de identificação quilombola
Authors: Lucini Marizete , Santos Andréia Teixeira dos
Published: February 2019

Este artigo propõe refletir sobre o Ensino de História e o pensamento decolonial na análise de processos de identificação étnico-racial em comunidades quilombolas, aqui compreendidos como espaços políticos de resistência às práticas sociais colonizadoras da memória ancestral. A discussão origina-se de pesquisa com abordagem qualitativa, do tipo estudo de caso, em desenvolvimento na Escola Estadual Quilombola Gilberto Amado, sobre os processos de identificação quilombola em comunidade remanescente de quilombo urbano Porto D’Areia – Estância/Sergipe. O aporte  teórico ancora-se no pensamento decolonial ao questionar todas as formas de colonização do saber, do poder e do ser.  Espera-se contribuir para a superação do olhar colonizador que inferioriza o negro e interfere no processo de reconhecimento da identidade quilombola.
ANEMIA FERROPRIVA ASSOCIADA À INFECÇÃO POR ANCILOSTOMÍDEO
Authors: Teles Marcelo Felipe Pereira , Gomes Sandra Lima Rosa
Published: February 2019

Anemia ferropriva é um dos distúrbios mais frequentes em países desenvolvidos e em desenvolvimento, classificada pela Organização Mundial de Saúde (OMS) como uma condição na qual o conteúdo de hemoglobina do sangue apresenta-se abaixo dos valores de referência considerados normais para a idade, sexo e estado fisiológico. A anemia por deficiência de ferro é considerada um transtorno nutricional que atinge principalmente o desenvolvimento de crianças entre 0 e 5 anos, idosos e mulheres, principalmente gestantes, causada por vários fatores, entre eles alguns parasitas intestinais como os ancilostomídeos. Esses parasitas podem reduzir em até 20% do ferro ingerido na dieta, o que pode resultar em anemia por deficiência de ferro caracterizando um problema de saúde pública que afeta as comunidades mais pobres e desfavorecidas, especialmente em áreas rurais em que as pessoas possuem o hábito de andar descalças. Diante disso, este estudo tem como objetivo descrever os principais fatores associados à infecção por ancilostomídeo, que contribuem para a instalação do quadro de anemia ferropriva.  Foi possível observar que a infecção por ancilostomídeo está diretamente relacionada à anemia ferropriva devido à lesão intestinal causada por esse parasita. Sendo assim, a adoção de medidas preventivas e o diagnóstico precoce da infecção são importantes para o controle, tratamento e redução da incidência da doença.
ALEITAMENTO MATERNO NA PREVENÇÃO CONTRA INFECÇÕES GASTROENTÉRICAS
Authors: Campos Dara Nayanne Martins , Araújo Nayana Hayss , Silva Tamaira Barbosa , Machado Andréia Santa Rita , Soares Leidiane Amorim
Published: February 2019

O aleitamento materno é, indiscutivelmente, o alimento mais qualificado para crianças. Apresenta-se como fonte de nutrientes e compostos bioativos que auxiliam na maturação dos sistemas imunológico e gastrointestinal, garantindo proteção, fortalecimento físico e emocional ao lactente no decorrer do seu primeiro ano de vida. Todavia, isso ainda não é aceito por muitas mães que acabam interrompendo essa prática precocemente, facilitando o surgimento de infecções gastroentéricas, como por exemplo as enteroviroses. Este estudo teve como objetivo descrever os mecanismos de defesa presentes no leite materno associado à prevenção para as infecções gastrointestinais. Artigos publicados em revistas científicas, teses de pós-graduação e livros foram os meios utilizados como fontes de informações, a partir do ano 2009 até maio de 2018. Foi observado que o leite materno apresenta anticorpos, lactobacilos e substâncias imunorreguladoras que são essenciais para o pleno desenvolvimento do recém-nascido, além de oferecer proteção contra infecções gastrointestinais. A amamentação desfavorece a proliferação de microrganismos patogênicos no ambiente intestinal e, portanto, a amamentação exclusiva até os seis meses de idade deve ser constantemente estimulada, já que fornece ao recém-nascido mecanismos de proteção necessários para prevenção contra agentes infecciosos oportunistas, principalmente contra bactérias e vírus, microrganismos comumente relacionados a casos de diarreia infantil.
Primary sinonasal ameloblastoma - a rare cause of unilateral nasal obstruction
Authors: Cukic Ognjen , Oroz Aleksandar , Miladinovic Nenad
Published: February 2019

Introduction. Ameloblastoma is a rare, locally invasive benign jaw tumour, originating from odontogenic epithelium, and their presence in the sinonasal tract is usually due to their spread from the gnathic region of the maxilla. Primary sinonasal ameloblastoma is extremely rare, with only a handful of reported cases so far. The objective of this article was to describe a patient with a primary ameloblastoma of the right maxillary sinus and nasal cavity. Case outline. We report a case of a 67-year-old male patient with a year-long history of progressive unilateral nasal obstruction. Clinical and computed tomography examination revealed a mass in the right maxillary sinus and right nasal cavity. After an in-office biopsy under local anesthesia, which suggested the diagnosis of ameloblastoma, the patient underwent complete removal of the mass by a medial partial maxillectomy. Histopathologic analysis confirmed the diagnosis of ameloblastoma. Conclusion. Primary sinonasal ameloblastoma is clinically and radiographically similar to the more common pathology of this particular area and should be included in the differential diagnosis of the unilateral nasal obstruction. The treatment of choice is complete surgical resection. Due to the rarity of the disease, and a small number of cases described so far in the literature, there is still no consensus regarding the optimal surgical technique.
Treatment of slipped capital femoral epiphysis - a comparative study during twelve years period
Authors: Bukva Bojan , Ducic Sinisa , Radlovic Vladimir , Vrgoc Goran , Krivokapic Branislav , Jelaska Igor , Mandic-Jelaska Petra
Published: February 2019

Introduction/Objective. The purpose of this study was to compare two methods of treatment and to evaluate the advantages in the final outcome of transcervical fixation of the femoral head using one cannulated screw in the treatment of slipped capital femoral epiphysis. Methods. This study included 65 pediatric patients (35 boys and 30 girls), aged 6?16 years (average 11.86), during a 12-year period (2000?2012). We compared the slipping degree before and after the treatment (Southwick angle), the range of motion before and after treatment, and complication occurrence between two groups of children. The first group of children (26 patients) underwent closed reduction and cast immobilization (Group I). The other group (39 patients) was treated with transcervical fixation using one cannulated screw (Group II). Results. Comparing preoperative and postoperative Southwick angle, we found much better improvement in Group II, but without statistical significance between the two groups of patients (p = 0.09). Observing the range of motion of the hips before and after treatment, we found improvement in both groups of patients, especially in patients treated using transcervical fixation with cannulated screw (Group II). In complication occurrence, the patients in Group II had less complication occurrence compared to Group I (p = 0.02). Conclusion. The transcervical fixation using one cannulated screw has better clinical outcome and lower complication rate in relation to closed reduction and cast immobilization in the treatment of slipped capital femoral epiphysis.
Hospitalization characteristics of patients with glaucoma in Central and West Serbia
Authors: Kocic Sanja , Radevic Svetlana , Simic-Vukomanovic Ivana , Janicijevic Katarina , Janicijevic-Petrovic Mirjana , Mihailovic Natasa
Published: February 2019

Introduction/Objective. Glaucoma is a chronic disease that impairs the optic nerve irreversibly and can lead to serious loss of vision and blindness. As the most frequent out of all, primary open-angle glaucoma has a worldwide incidence of 2.4 million. The objective of this article is to examine the characteristics of glaucoma hospitalization patterns in Central and West Serbia in the 2006?2017 period. Methods. This study was a retrospective analysis of glaucoma hospitalizations in the Kragujevac Clinical Center from 2006 to 2017 (n = 1,751). All hospitalizations were divided according to discharge diagnoses into the following three subgroups: primary open-angle glaucoma, the primary closure glaucoma, and secondary glaucoma and other glaucoma types. Results. The average hospitalization rate for glaucoma is 5/10,000 inhabitants. The lowest rate was recorded in 2013 (1.8/10,000) and the highest in 2015 (9.3/10,000). The rehospitalization rate ranged from 0.5/10,000 in 2013 to 6.9/10,000 in 2015, with an average of 2.4 patients per 10,000. The most common glaucoma was secondary glaucoma and other glaucoma types (44.6%), followed by primary open-angle glaucoma (37.9%) and primary closure glaucoma (17.5%). The average hospitalization length was 6.5 ? 4.9 days and it decreased from the average 9.7 ? 6.5 (2006) to 5.5 ? 3.7 days (2013) (p < 0.01) in all glaucoma types. Conclusion. There was a significant reduction of the hospitalization length in all glaucoma types in Central and West Serbia. The hospitalization rates varied with a significant increase since 2013, which is the consequence of the increase in rehospitalization rates.
The importance of 6-MAM levels and morphine/codeine ratio in diagnosis of death among drug addicts
Authors: Jaksic Vladimir , Miric Dijana , Ilic Aleksandra , Matejic Suzana , Stevic Snezana , Vitosevic Zdravko
Published: February 2019

Introduction/Objective. Heroin is metabolized to 6-monoacetylmorphine (6-MAM) and morphine. The objective of this study is to examine 6-MAM, morphine, and codeine relationships in order to distinguish deaths related to heroin consumption from deaths related to morphine and/or codeine consumption. Methods. The autopsy blood and urine samples from 45 opioid drug addicts were examined. Gas chromatography/mass spectrometry was applied to evaluate morphine, 6-MAM, and codeine. Two groups were formed: 6-MAM-positive (n = 35) and 6-MAM-negative (n = 10). Results. Compared to the 6-MAM-negative group, blood morphine levels were higher in the 6-MAMpositive group (p = 0.022), while blood codeine levels were similar (p = 0.575). In the 6-MAM-negative group, the blood morphine/codeine ratio was 8.3, and it was 4.3 in the 6-MAM-positive group. There was no difference between the groups regarding urine morphine levels (p = 0.859). The urine morphine/ codeine ratio was 6.2 in the 6-MAM-negative group, whilst it was 32.2 in the 6-MAM-positive group. In the blood samples, morphine and codeine concentrations were significantly correlated (r = 0.607; p = 0.006). In urine samples, correlations between morphine and codeine (r = 0.766; p < 0.001), morphine and 6-MAM (r = 0.650; p < 0.001), as well as codeine and 6-MAM (r = 0.620; p < 0.001), were also significant. Conclusion. Analyses of 6-MAM and morphine/codeine ratio in blood and urine autopsy samples may be used as diagnostic tools to distinguish deaths related to the consumption of different opioid drugs.
Performance investigation and exergy analysis of vapor compression refrigeration system operated using R600a refrigerant and nanoadditive compressor oil
Authors: Karthick Munuswamy , Karuppiah Senthil , Kanthan Varatharajan
Published: February 2019

Compression of vaporized refrigerant is the essential process of the refrigeration cycle which is performed by using a compressor. The amount of power consumed by a refrigeration system is governed by the work input given to its compressor, which also determines the COP of the system. By reducing the work input given to the compressor, the power consumption of refrigerator is reduced along with the improvement in its COP. Nowadays, nanoparticles have emerged as the new generation additives in various working fluids because of their remarkable ability to improve the heat transfer, tribological and other thermophysical properties of the base fluid. In such a vein, we propose a compressor oil based nanofluid prepared by dispersing nanoparticles into the conventional compressor oil. In the present study, four samples of nanoadditive compressor oil were prepared by dispersing the nanoparticles like Al2O3, TiO2, and ZnO into the conventional mineral oil as a lubricant. The tribological properties of this four samples were studied, out of which one sample gave a better lubrication and heat transfer properties which are considered as one of the key parameters for reducing work input to the compressor, this can result in reduced power consumption, with enhancement of COP. These results are analyzed experimentally by carrying out performance and exergy analysis in a vapor compression refrigeration system, using R600a as a refrigerant. The experimental results show that, there is an improvement of COP by 14.61% and exergy efficiency by 7.51%. Also, the efficiency defect in the major components of vapor compression refrigeration system has been reduced effectively.
Analysis on flow separation characteristics of last stage blade in steam turbine under small volume flow condition
Authors: Cao Lihua , Wang Wenlong , Luo Huanhuan , Hu Pengfei , Li Zhengwen , Zhang Yanjun , Ma Tingshan
Published: February 2019

The inlet steam flow of steam turbine is obviously reduced and even in the state of small volume flow when the thermal power unit is involved in peak load operation, which greatly influences the safety of steam turbine. The last stage flow field of steam turbine under small volume flow condition is calculated by the CFX to study the formation, development, influencing range, and the variation rule of the flow separation vortex cores. The results show that the flow separation vortices appear near last stage blade at 30% of the rated volume flow. With the decrease of volume flow, the flow separation vortices gradually spread to the root of blade. When the volume flow decreases to 8% of the rated volume flow, the flow separation vortices almost occupy the whole blade. The position of the flow separation vortex cores shifts from 72.7% of the relative blade height to 49.1%. The results of this paper lay a foundation for the safety analysis of the last stage blade in the steam turbine under the small volume flow condition.
Effects of gaseous slip flow and temperature jump on entropy generation rate in rectangular microducts
Authors: Ghaffari Abuzar , Khan Waqar , Mustafa Irfan
Published: February 2019

In this study, the influence of slip flow and temperature jump on the entropy generation rate are investigated in rectangular microducts. The Knudsen numbers are considered in the range between 0.001 and 0.1, and the aspect ratio lies between 0 and 1. The dimensionless governing equations are solved numerically using Chebyshev spectral collocation method, and the dimensionless velocity and temperature gradients are employed in the entropy generation model. The influences of the dimensionless numbers including Bejan number and irreversibility distribution ratio on the entropy generation rates are investigated and discussed through surface plots and contour diagrams. It is demonstrated that the minimum entropy generation rate exists corresponding to an optimal aspect ratio for each dimensionless number. This minimum entropy generation rate depends upon the nature of dimensionless numbers.
District heating substation elements modeling for the development of the real-time model
Authors: Lazarevic Sladjana , Congradac Velimir , Andjelkovic Aleksandar , Kljajic Miroslav , Kanovic Zeljko
Published: February 2019

In the heating system of residential and commercial buildings, heating substation has an important role because it is used as a separator between primary and secondary supply sides. In this paper, we focused on the development of the simulation model of all heating substation elements, which influence the change of relevant parameters: water temperature, flow, and pressure. The primary objective of the paper is to analyze and develop mathematical models of the heat exchanger, control valve, three-way valve and frequency-regulated centrifugal pump that are configurable and generic as much as possible, so they can be used for the development of the model that could operate in real time. A real-time model could be used as a suitable replacement for an actual physical system in the process of testing and improvement of the control system performance. Different elements setups of district heating substation are considered, and the modelbased simulation is presented for one of them.
Focal pruritus and alopecia in lumbar area in guinea pigs
Authors: Vucicevic Milos , Dosenovic Milan , Mitrovic Marko , Simovic Nikola , Milcic-Matic Natalija , Anicic Milan
Published: February 2019

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Can Simple Metaphors Be Used as Decision Aids to Promote Professional Skepticism?
Authors: Durkin Mary P. , Rose Jacob M. , Thibodeau Jay C.
Published: February 2019

This study examines the potential for metaphorical priming to promote professional skepticism. Results of an experiment with 99 senior auditors from two Big 4 audit firms indicate that reading metaphors that are entirely unrelated to audit evidence can promote professional skepticism and influence auditors' judgments. Relative to auditor participants who did not read a metaphor, participants who read a metaphor related to concerns about the honesty of the sources of information (client-skeptical metaphor) or concerns about one's own ability to detect problems (self-skeptical metaphor) assessed higher levels of fraud risk. These auditors also perceived that fraud-based explanations were more likely to cause fluctuations in client ratios. Importantly, metaphorical primes improved auditors' fraud-related actions and caused them to focus on issues that were the most likely explanations for the audit evidence. Results suggest that metaphorical priming may represent a powerful and efficient tool for promoting high-quality and professionally skeptical judgments.
FOREIGN OWNERSHIP, PRODUCTIVITY, AND ECONOMIC CRISIS
Authors: . Suyanto
Published: February 2019

This paper evaluates the productivity benefit from the present of foreign ownership in manufacturing firms. The productivity benefit is analysed for the period before crisis (19881996) and the period crisis onwards (1997-2000). Using the methodology of stochastic production frontier, the results show that foreign ownership generates positive productivity benefit to local manufacturing firms, both during the before crisis period and during the crisis onwards period. An interesting result emerges when comparing the two periods. Although positive spillover benefits exist in both periods, the coefficient of FDI Spillovers is larger during the period of crisis onwards, suggesting that the productivity benefit increase after economic crisis. These findings support an argument by Takii (2007) that economic crisis has positive impact on the productivity spillovers of FDI.
FACTOR ANALYSIS TO GUEST SATISFACTION DIFFERENTIATED BY INCOME SEGMENT
Authors: Aryanto Rudy
Published: February 2019

Currently fast growing researches on the factors of customer satisfaction, especially in the services sector and tourism. Indonesian as a famous tourism market is going through a period of great change in the current era in term of the demand for tourism destination attraction. One of the tourism destination is Ragunan Zoo Park. To get more market, management should be more pay attention to visitor by increasing in visitor’s satisfaction so that they become a loyal visitors and they will bring more customers to visit Ragunan. The Ragunan’s visitors income can divide in two segment: first, The visitors that have income more regional salary rate (UMR), second, The visitors that have income under regional salary rate. The objectives in this research are: to know are there any variables that differentiation visitor’s satisfaction. Variables that being used base on the customers satisfaction dimension and overall destination product. Data processing and analyzing use Discriminant Analysis. This method was hoped could answer the research objectives. Over all, The research shows any significant differentiation between two groups. Variables that make different are: games ticket, food and beverages price, education image, access, parking facility and count of animals.
PERCEIVED VALUE DIMENSIONS OF SHOPPING TOURISM
Authors: Roostika Ratna
Published: February 2019

Superior customer value is essential to win competition. The perception of customer value has grown in interest since it has been found to have stable impacts on satisfaction, behavioral intentions and ultimately business performance. Considering that the most common definition of perceived value refers to the trade-off between benefits and sacrifices, thus, this study adopts the second-order formative conceptualization of perceived value and examined its links to satisfaction and loyalty. Four main tourist shopping locations in Yogyakarta were used to collect the data. By applying Partial Least Squares to test the model in the tourism shopping context, the results indicate that perceived value has positive relationships with satisfaction and loyalty. Additionally, it was found that the total contribution of perceived value and satisfaction on loyalty were only small.
TOURISM DEMAND FOR BALI-THE HEGY APPROACH FOR SEASONAL UNIT ROOT TEST
Authors: Wiyasha Ida Bagus Made
Published: February 2019

Tourism plays an important economic role for a destination. This study aims to investigate the behavior of seasonal direct tourist arrivals to Bali. To achieve the aforementioned objective archival data of direct tourist arrivals to Bali from 2001 to 2010 were used. Error Correction Model (ECM) and HEGY approach were applied to analyze the behavior of seasonal tourist arrivals. Wald test was applied in joint test for quarterly parameter. Cusum test were applied to examine the parameter stability for the periods mentioned above. USA, UK, and Japan tourist arrivals were the dependent variables while exchange rates and inflation rates for those mentioned countries were independent variables of the model. The findings of the study are as follows. The ECM results for Japan revealed that in the short run and the long run as well the exchange and inflation rates were negatively related to arrivals. For UK, in the short run exchange rates negatively related to arrivals while inflation rates exhibited positive relation to arrivals. For the US, all exchange rate and inflation rates were positively related to arrivals. Cusum test revealed the following. Japan arrivals exhibited relatively stable parameter for the periods of 2001-2010. UK arrivals showed parameter instability; while US arrivals experienced relatively stable parameter for the periods mentioned earlier. Wald test results showed that all arrivals, USA, UK, and Japan contained a unit root for their quarterly data.
PEMASARAN TRADISIONAL DAN PEMASARAN KEWIRAUSAHAAN: PENGARUHNYA TERHADAP KINERJA USAHA KECIL ETNIS JAWA DAN MADURA
Authors: Hadiyati Ernani , Kresnaini Enlik
Published: February 2019

The role of SMEs in the national economy has involved the government, it is appropriate in the Program of the National Medium Term Development Plan 2004-2009. One small problem is the marketing and generally focused on three things: (1) product market competition, (2) access to market information, and (3) support the institutional business. To overcome the problems of marketing, human resource needs in conducting marketing activities to have a high entrepreneurial spirit. The study population is small businesses: industrial clothing, embroidery, batik, shoes, sandals, handbags, and luggage, furniture, ceramics and printing. The number of samples in this study is set at: 100 respondents including Javanese and Madurese 50% Ethnic 50%. Data analysis techniques used are grouped into two categories, namely descriptive statistics and structural equation model (Structural Equation Modeling). Descriptive statistics were used to analyze data in ways that explain or describe the data have been collected and are not intended to create a generally accepted conclusions or generalizations. The results showed that: Traditional Marketing significantly influence with entrepreneurship. Traditional marketing significant effects on business performance. Entrepreneurship significantly effects on entrepreneurial marketing. Entrepreneurship significant effect on business performance. Marketing Entrepreneurship significant effect on business performance. There are differences between ethnic entrepreneurs and ethnic Javanese Madura, when viewed in terms of entrepreneurship, entrepreneurial marketing and business performance. However, if viewed in terms of traditional marketing, there is no difference between ethnic Madurese and Javanese businessmen.
THE ROLE OF EXCHANGE IN CUSTOMER LOYALTY OF SOCIAL NETWORK SITES
Authors: Anandya Dudi
Published: February 2019

Exchange has been known as the subject matter of Marketing. In this decade, Internet has enabled people to connect and exchange information to others, regardless of time and space. This condition leads to a new phenomenon, known as social networking through social network sites. In social network sites members find new kinds of exchange, which is information exchange. Memberships in many social network sites are free, which means that everyone is free to join or leave it. In that case social network providers must ensure that members keep using their site. The aim of this study is to test and analyze the direct and indirect effect of exchange to loyalty. The Unit of analysis in this study were members of social networking sites Friendster and Facebook. There are 256 respondents participate in this research. The result shows if community members keep exchange activity, they will loyal to the community. Direct effect has greater impact on loyalty than indirect effect. This means that social network company must encourage their member to exchange information actively.
MARKET SHARE AND CUSTOMER EQUITY MEASUREMENT USING MARKOV CHAIN
Authors: Furinto Asnan , Heryadi Yaya , Budiono Tri Asih
Published: February 2019

Various techniques have been developed to measure firm's market share and the return on investment (ROI) of firm's marketing expenditures. However, most of those techniques are usually used to assess the past performance of a marketing program, using history of longitudinal data instead of expected future performance of a planned marketing program. In the absence of historical data base, measurements of expected ROI could still be carried out using a cross sectional survey, evaluating customer future purchase intentions as influenced by a new loyalty program to be launched by the firm in near future. Using survey of domestic airline passengers and Markov Chain approach, the model incorporates competition whereby customers are free to switch from one carrier to another from time to time. Expected ROI of loyalty program is measured by changes in the customer equity. Using MatLab software, future market share of Lion Air, Mandala Air, and Merpati Airline could be estimated quite accurately, and subsequently, changes in customer equity could be measured. Loyalty programs indeed induce changes in customers' future share of wallet and customer equity. Managers are encouraged to regularly conduct customer survey to guide them prior to launching a marketing action, using changes in customer equity as the ultimate dependent variable of ROI measurement.
STRATEGY TO IMPROVE BRAND AWARENESS
Authors: Liando Monica Francesca , Setyawati Christina Yanita
Published: February 2019

Brand strategy is an important thing that has to be built by the company to strengthen the relationship between a company and its customers to provide benefits for the company so that the company is able to win the competition in the industry (Sadat, 2009). Wheeler (2013) explains that the company can create a brand strategy to provide a strong sense so that it can compete with the competitors. The development of creative industries in Indonesia made a great contribution in the economy of Indonesia where the craft sector became the biggest contributor (Indonesia Kreatif, 2014). Companies which engaged in the craft sector are increasing, so that the companies face intense competition. It means that the company needs to build a brand that build good perception and gain the trust of the customers. This study aims to find strategies that can increase brand awareness by conducting case study on Empress Box company. Empress Box that founded in January 2014 is a company engaged in the creative industries. The company produce exclusive jewelry made of silver. The method used in this study is a qualitative with case study approach. The result of this study suggest three strategies. The first strategy that can increase brand awareness is the brand building characteristics that determine the segmenting, targetting, and positioning. The second strategy is to do integrated marketing communication (IMC), by using social media, joining competitions and exhibitions. The third strategy is product placement by doing endorsements and displaying the products in multibrand stores.
INNOVATIVENESS SURVEY ON MANUFACTURING COMPANIES IN TASIKMALAYA CITY
Authors: Suroso Edy , Primiana Ina
Published: February 2019

Innovation is one of most important sources of competitive advantage. The purpose of this paper is to analyze innovativeness by using the 55 operations managers of manufacturing companies in Tasikmalaya City as respondents. The results showed the four types of clusters of Innovativeness consisting of (1) Leading Innovator that have the out class value than the others in every aspects of innovativeness, (2) Followers cluster is as the very low radical product innovations capability, (3) Inventors are very strong in radical product innovations, while (4) Lagers are at the lowest scores in all innovation types among the clusters. Based on ANOVA, it is concluded that every group of innovation type has its own success difference. The leading innovators type has the highest mean of business success measured by the comparison innovations type among groups in the growth of sales.
THE EFFECT OF IMAGE AND SERVICE QUALITY ON CUSTOMER COMMITMENT WITH TRUST MEDIATION (A Study at PUSKESMAS In-Patients, Jakenan, Regency of PATI)
Authors: Marlien R.A. , R R Alimuddin , Muslihin Ali
Published: February 2019

Community health center as a community health service center has an important value in building a healthy and productive society. The existence of in-patient service at a public health center has been highly expected by the public who suffer from illnesess. The general public expects the nearest health center to resolve arising issues related to their illnesses. The purpose of this study was to test the effect of the Image and the Service Quality on Customer Commitment with Trust mediation. The data compiled were analysed by Linear Regression. The findings show that the Image and Service Quality significantly show a direct effect to Trust and Customer Commitment, but the Trust variable do not mediated Image and Customer Commitment. The majority of in-patients are farmers and they are more likely to feel safe and confident when treated in health centers.