bluuebunny/crossref_metadata_2025 huggingface dataset:
ИСПОЛЬЗОВАНИЕ БИОАКТИВНЫХ ПЕПТИДОВ ДЛЯ ОБЕСПЕЧЕНИЯ КАЧЕСТВА И ХРАНИМОСПОСОБНОСТИ ХЛЕБА
Authors: Резниченко Ирина Юрьевна , Акопян Гиоргий Сергеевич
Published: April 2023

Разработка и внедрение в практику инновационных технологий, оценка влияния новых биологически активных веществ в форме биопептидов на качество продуктов питания является актуальным направлением исследований. Отдельное направление исследований связано с использованием пептидов в качестве природных консервантов, т.к. порча и загрязнение пищевых продуктов, зачастую связанные с микроорганизмами, особенно бактериями и грибками, приводят к потерям продуктов питания и серьезным заболеваниям пищевого происхождения. Пептиды обладают высокой биологической активностью, характеризуются антимикробными, бактерицидными, противовирусными свойствами в наноконцентрациях, что определило их перспективность использования в технологиях пищевых продуктов. Цель работы заключалась в обосновании применения БАД (ферментативный гидролизатфабрициевой сумки цыплят бройлеров) в технологии производства хлеба пшеничного для увеличения срока хранения и улучшения качественных характеристик хлеба.Объектами исследования являлись модельные образцы хлеба пшеничного из муки высшего сорта с добавлением БАД. В качестве методов исследования применяли методы анализа, систематизации, обобщения информационных данных поисковых отечественных и международных систем за последние пять лет, стандартные и отраслевые методы контроля сырья и изделий хлебопекарного производства. Установлено, что величина упека хлеба достоверно снижается с увеличением дозировки БАД, влажность мякиша хлеба незначительно увеличивается (на 4%), что подтверждает данные о гидрофильности вносимых пептидов, кислотность хлеба увеличивается с увеличением дозировки гидролизата. Пористость мякиша и удельный объем хлеба с увеличением дозировки гидролизата увеличились на 7% и 31 % соответственно.Оценка показателей безопасности выявила, что хлеб с 50% заменой раствора соли на БАД в течение 120 часов сохранял свои первоначальные свойства, хлеб с полной заменой – 168 часов, контроль – 72 часа. Установлен рекомендуемый срок хранения хлеба с полной заменой солевого раствора БАД 144 часа(6 суток).Исключение соли из рецептуры при внесении 100% БАД позволяет отнести разработанный хлеб к ахлоридному, т.е. хлебу специализированного назначения. Из результатов исследований следует, что ферментативные гидролизаты белка фабрициевой сумки, содержащие антимикробные пептиды, являются многообещающими альтернативами для использования в качестве натуральных консервантов, но также необходимы новые исследования для подтверждения полученных данных и оценки других показателейкачества и отсутствия аллергенности хлеба.
МОДИФИКАЦИЯ МЕТАЛЛОРЕЖУЩИХ ПЛАСТИН ИЗ БЕЗВОЛЬФРАМОВОГО ТВЕРДОГО СПЛАВА КНТ16 МОЩНЫМ ИОННЫМ ПУЧКОМ
Authors: Бадамшин Артем Маратович Бадамшин Артем Маратович , Ковивчак Владимир Степанович , Крутько  Андрей Александрович Крутько  Андрей Александрович , Бургонова  Оксана Юрьевна Бургонова  Оксана Юрьевна
Published: April 2023

В работе исследовано влияния мощного ионного пучка наносекундной длительности на изменение морфологии, механических свойств и эксплуатационных характеристик металлорежущих пластин из безвольфрамового твердого сплава марки КНТ16 (TiCN–Ni–Mo). Установлено, что воздействие мощного ионного пучка приводит к существенному изменению износостойкости режущих пластин при токарной обработке прутков из стали 40ХН. Определено оптимальное число импульсов облучения, при котором режущая пластина испытывает наименьший износ при проведении испытаний. С помощью растровой электронной микроскопии обнаружено, что воздействие мощного ионного пучка в диапазоне числа импульсов от 1 до 3 приводит к формированию однородного оплавленного поверхностного слоя образцов, что, в свою очередь, приводит к повышению их теплостойкости при температуре выдержки T = 800 ºC. Исследовано влияние числа импульсов облучения мощного ионного пучка на микротвердость облученных образцов.
Results of the salmon fishing season in the North Pacific in 2022
Authors: Marchenko S. L.
Published: April 2023

Results of the 2022 salmon fishing season in the North Pacific are presented, including the data on landing of pacific salmon in the Far East of Russia, on the Pacific and Arctic coasts of North America and in Japan.
Asymmetric synthesis of sulfoximines, sulfonimidoyl fluorides, and sulfonimidamides enabled by an enantiopure bifunctional S(VI) reagent
Authors: Teng Shun , Shultz Zachary , Shan Chuan , Wojtas Lukasz , Lopchuk Justin
Published: April 2023

An increased interest to expand the three-dimensional chemical space for the design of new materials and medicines has created a demand for isosteric replacement groups of commonly used molecular functionality. The structural and chemical properties of chiral S(VI) functional groups provide unique spatial and electronic features compared to their achiral sulfur- and carbon-based counterparts. Manipulation of the S(VI) center to introduce structural variation with stereochemical control has remained a synthetic challenge. The stability of sulfonimidoyl fluorides and the efficiency of sulfur fluorine exchange (SuFEx) chemistry has enabled the development of an enantiopure bifunctional S(VI) transfer reagent (t-BuSF) to overcome current synthetic limitations. Here, this reagent platform serves as a chiral SuFEx template for the rapid asymmetric synthesis of over seventy different sulfoximines, sulfonimidoyl fluorides and sulfonimidamides with excellent enantiopurity and good overall yields. Furthermore, the practical utility of t-BuSF was demonstrated in the syntheses of enantiopure pharmaceutical intermediates and analogs.
Spatiotemporally tuned colloidal phoretic leap in an altering multivalent interaction field
Authors: Shandilya Ekta , Rallabandi Bhargav , Maiti Subhabrata
Published: April 2023

Multivalency-mediated interactions play an important role in governing dynamicity and self-assembly in biological systems. Despite its significance in supramolecular material chemistry to biomedicine, the role of multivalency in modulating colloidal transport or phoresis remains largely unexplored. Here, combining theory and experiment, we report diffusiophoretic motion of a positively-charged catalytic microbead during its multivalent interactions with a gradient of adenosine mono-, di- and trinucleotides (AM/D/TP) both in micro- and macroscale regimes. We find that the extent of drift diminishes with increasing number of phosphates. Subsequently, we exhibit nucleotide-specificity of the colloid in catalyzing a proton-transfer reaction, which in turn alters its phoretic behaviour. Finally, we demonstrate spatiotemporal control over colloidal phoretic leap (a sudden increase in phoretic velocity) and population dynamics driven by enzymatic downregulation of multivalent interactivity, which has been achieved by controlling ATP hydrolysis in situ. These findings open up avenues for utilizing multivalent surface-mediated catalytic activity to achieve precise control of particle transport relevant to reaction-diffusion driven spatiotemporal processes.
Marketing Frontiers
Authors: N Selvalakshmi
Published: April 2023

Marketing is the process of exploring, creating, and delivering value to meet the needs of target in terms of goods and services; potentially including selection of a target audience; selection of certain attributes or themes to emphasize in advertising.
Aktívna a pasívna bezpečnosť: chodci
Authors: Vertaľ Peter
Published: April 2023

Problematika aktívnej a pasívnej bezpečnosti chodcov je často diskutovanou témou v oblasti prevencie dopravných nehôd a následkov spôsobených dopravnou nehodou. Vývoj v oblasti aktívnej bezpečnosti si kladie za cieľ minimalizovať zrážku s chodcom a predísť tak zraneniam prípadne smrti pri dopravnej nehode tým, že k zrážke nedôjde. Na rozdiel od aktívnej bezpečnosti je pasívna bezpečnosť vozidiel orientovaná k tomu, aby už v prípade ak dôjde ku kolízii vozidla s chodcom, boli zranenia chodcov čo najmenšie. Publikácia si kladie za cieľ v čo najširšej miere a v danom rozsahu opísať pohyb chodcov a ich možné zranenia pri pohybe v oblasti cestných komunikácii. Značná časť publikácie je venovaná opisu hardvérových riešení vozidiel, ktoré prispievajú k zabráneniu dopravnej nehody alebo k minimalizovaniu zranení. Výber z komplexných testovacích procedúr, ktoré slúžia na overovanie výkonnostných charakteristík testovaných vozidiel poukazuje na zložitosť pri vývoji nových vozidiel, aby naplnili technické predpoklady noriem. Na základe týchto testovacích noriem je zrejmé do akej miery je nimi ovplyvnený dizajn vozidiel v súčasnej dobe.
Respondiendo a las necesidades de salud sexual y reproductiva de las migrantes venezolanas en Lima
Authors: Pesantes M. Amalia , Cortez Leonardo , Scaramutti Carolina , Portocarrero Jill , Haghparast-Bidgoli Hassan , Miranda J. Jaime
Published: April 2023

Objetivo.

Presentar y analizar la respuesta que el sistema de salud peruano viene dando a las necesidades en salud sexual y reproductiva de las mujeres venezolanas que radican en la ciudad de Lima, Perú e identificar algunas de las razones que nos permite entender esta respuesta.

Métodos.

La información se recogió mediante entrevistas a profundidad semiestructuradas por vía telefónica a 30 mujeres venezolanas, 10 trabajadores de salud y 2 funcionarios del Ministerio de Salud.

Resultados.

A partir de las experiencias de mujeres venezolanas que acudieron a estos servicios durante el 2019-2020 y de las perspectivas del personal y autoridades de salud presentamos un análisis de la capacidad y limitaciones que los servicios de salud públicos tienen para atender las necesidades de salud sexual y reproductiva de esta población. Los testimonios de las mujeres migrantes reportan una experiencia positiva con un sistema de salud que, a pesar de las deficiencias, responde a las necesidades de salud sexual y reproductiva más comunes. Estas coinciden con los testimonios del personal de salud y con las de las autoridades quienes enfatizan la existencia de políticas prioritarias para la atención de la Salud Sexual y Reproductiva.

Conclusión.

Este estudio muestra cómo un marco de prioridad nacional (disminuir la mortalidad materna), acompañado de mecanismos operativos de protección social (como el Seguro Integral de Salud), se convierten en instrumentos complementarios, que repercute de manera positiva y extiende beneficios para las y los migrantes, a pesar de no haber considerado a esta población durante el diseño de estas políticas.
Síntesis de evidencia y recomendaciones: directriz para el tamizaje, la detección y el tratamiento del cáncer de cuello uterino
Authors: Organización Panamericana de la Salud
Published: April 2023

Objetivos.

Sintetizar las recomendaciones desarrolladas por la Organización Mundial de la Salud (OMS) con el fin de mejorar la calidad del cuidado y los desenlaces en salud sobre el tamizaje y tratamiento de las mujeres con lesiones precancerosas para la prevención del cáncer de cuello uterino.

Métodos.

Las directrices elaboradas por la OMS siguen los métodos de elaboración de la directriz GRADE (Grading of Recommendations Assessment Development and Evaluation) del Manual para el desarrollo de directrices de la OMS. Se llevó a cabo una síntesis de las recomendaciones de dos directrices de OMS. Adicionalmente, se realizó una búsqueda sistemática en PubMed, Lilacs, Health Systems Evidence, Epistemonikos y literatura gris de estudios desarrollados en las Américas con el fin de identificar barreras, facilitadores, estrategias de implementación e indicadores.

Resultados.

Se formularon 19 recomendaciones y 10 puntos de buena práctica para el tamizaje de lesiones precancerosas del cuello del útero y el tratamiento del cáncer de cuello uterino. Se identificaron barreras y facilitadores para la implementación y se crearon indicadores de adherencia y resultado.

Conclusiones.

Las recomendaciones formuladas proveen orientación para mejorar la calidad del cuidado y los desenlaces en salud sobre el tamizaje y tratamiento de las mujeres con lesiones precancerosas para la prevención del cáncer de cuello uterino, con consideraciones para su implementación en América Latina y el Caribe.
Statistical extension some types of symmetrically continuity
Authors: Evirgen Pelda , Kucukaslan Mehmet
Published: April 2023

In this paper, the notions symmetric continuity, weak continuity, weak symmetric continuity which wasintroduced in [P.Pongsriiam and T.Thongsiri, Weakly symmetrically continuous function, Chamchuri Journal of Mathematics, vol 8(2016),49-65 ] are generalized by using natural density defined on N. Among the others some basic properties of generalized form of symmetrically continuity is investigate with several useful examples.
The Lean Project Approach to Anticipate Delays in the Construction of 3.5 GT Fishing Boats (Case Study at PT. X)
Authors: Hidayah Asfarina
Published: April 2023

Projects generally have a deadline for completion. So far, PT. X often experiences delays in project completion. The problem is that waste often occurs in the production process. As a result, the company can suffer losses if waste m is not minimized immediately. The purpose of this research is to identify waste that contributes to delays in the construction of 3.5 GT fishing vessels and to increase the Value Stream by using the Lean Project methodology to estimate delays. Utilizing the Lean Project methodology, this research identifies and maps waste in every manufacturing step.The recommended value stream creation is based on the total time spent on each component, which is calculated from 18.7 hours to prepare the mould, 26.5 hours to manufacture the hull, 28 hours to assemble, 112 hours to manufacture the steering system, and 88 hours to manufacture the finish. The initial value stream for one unit of the Sumbawa 3.5 GT fishing vessel is 273 hours, or 34 days, according to the estimated time for each stage of the production process. The planned lead time is 678 hours or 84 days less than the previous lead time. The difference from the anticipated value stream is 405 hours or 51 days.
A Comparison of Nonparametric Statistics and Bootstrap Methods for Testing Two Independent Populations with Unequal Variance
Authors: Wanishsakpong Wandee , Sodrung Kantima , Thongteeraparp Ampai
Published: April 2023

The common parametric statistics used for testing two independent populations have often required the assumptions of normality and equal variances. Nonparametric tests have been used when assumptions of parametric tests cannot be achieved. However, some studies found nonparametric tests to be too conservative and less powerful than parametric tests. Bootstrap methods are also alternative tests when assumptions of parametric tests are violated, but they have small size limitations. Later, nonparametric tests when pooled with the bootstrap methods may overcome the powerful test and small sample sizes issue. Thus, the purpose of this study was to apply the bootstrap method together with nonparametric statistics and compare the efficiency of nonparametric tests and bootstraps methods when pooled with nonparametric tests for testing the mean difference between two independent populations with unequal variance. The Yuen Welch Test (YW), Brunner-Munzel Test (BM), Bootstrap Yuen Welch Test (BYW) and Bootstrap Brunner-Munzel Test (BBM) were studied via Monte Carlo simulation with non-normal population distributions. The results show that the probability of a type I error of all four test statistics could be controlled for all situations. The Brunner-Munzel test (BM) had the highest power and the best efficiency in the case of mean difference ratio increases. The Bootstrap Yuen Welch Test (BYW) had the highest power when the sample size was small.
Investigation of the readiness level of Syrian students having received preschool education and not having received preschool education for primary education
Authors: UZUN Merve , GÖK Bilge , ARSLANTAŞ Tuğba
Published: April 2023

The current study aims to determine the readiness level of Syrian students having received and not having received pre-school education for primary education. To this end, on the basis of the main research question “What are the opinions of primary teachers about the readiness level of Syrian students having received and not having received pre-school education for primary education?”, their level of readiness was investigated in terms of their cognitive, physical, socio-emotional, language and self-care skills. The current study employed the case study design, one of the qualitative research methods. The study group is comprised of 15 primary teachers teaching first graders including Syrian students attending schools in the city of Şanlıurfa, which is located in the Southern Anatolian region of Turkey and where the Syrian population is intense. The participating teachers were selected by using the criterion sampling method. The data were collected through the semi-structured interview technique. In the analysis of the collected data, the content analysis method was used. As a result of the study, it was concluded that the Syrian students having received pre-school education are more ready for primary education in terms of their cognitive, physical, language, socio-emotional and self-care skills and that the Syrian students not having received pre-school education encounter many problems in the first grade of primary education.
Dursun, N. (2023). Roman ve Coğrafya. İstanbul: Metamorfoz (Okur Kitaplığı)
Authors: GÜVENİLİR Yasemin
Published: April 2023

Roman ve Coğrafya, Necla Dursun’un 2023 yılında edebiyatla coğrafyayı bir arada işlediği bir çalışma. 207 sayfadan oluşur. Metamorfoz Yayıncılık’ın alt markası Okur Kitaplığı’nın yayınlarından. Eserin genel yayın koordinatörü ve yayın yönetmeni Ünsal Ünlü, editörü Feyza Pınar Yaşar ve Ünsal Ünlü, musahhih Ayşenur Muslu, kapak tasarımcısı Neslihan Tokdemir’dir.
Orhan Kemal’in Ekmek Kavgası öyküsünün biçembilimsel çözümlemesi ve Türkçenin yabancı dil olarak öğretimine uygunluğu
Authors: MERCAN Öykü
Published: April 2023

Yabancı dil olarak Türkçenin öğretimindeki güncel sorunlardan biri Türkçeyi yabancı dil öğrenenler için özel hazırlanmış ya da uyarlanmış okuma materyallerinin sayıca ve nitelik bakımından yetersiz olmasıdır. Okuma becerisi için genellikle dil öğretimi için özel hazırlanmış kurmaca ya da üzerinde hiçbir uyarlama yapılmadan alınan özgün metinler kullanılmaktadır. Ancak bu metinlerin Türkçeyi yabancı dil olarak öğrenen hedef kitlenin ihtiyacına göre değerlendirilmesi ve daha sonra öğretim sürecine dâhil edilmesi elzemdir. Biçembilimsel çözümleme, metinlerin hem dilbilgisel hem de anlam boyutunu ele almaktadır. Bu nedenle metinlerin öğretim sürecine dâhil edilmesi öncesinde yapılacak değerlendirmede başvurulabilecek yöntemler arasındadır. Bu çalışmanın amacı, Orhan Kemal’in Ekmek Kavgası isimli kısa öyküsünü Toolan’ın (1990) metin merkezli dilbilimsel eleştiri yöntemi ile çözümlemek ve elde edilen veriler doğrultusunda Türkçenin yabancı dil olarak öğretimine uygunluğunu belirlemektir. Biçembilimsel çözümleme sonucunda elde edilen bulgular Maarif Vakfı Türkçenin Yabancı Dil Olarak Öğretimi Programındaki dil bilgisel yeterlilikler kapsamında değerlendirilmiştir. Kısa öykünün yapısal olarak B2 seviyesindeki dil bilgisi yapılarına uygun olduğu tespit edilmiştir. Öyküde yerel ağız kullanımına ve tarihî atıflara sıkça rastlanması öykünün kültürel boyutunu zenginleştirse de anlamsal boyutu öğreniciler için daha karmaşık hâle getirmektedir. Bu nedenle anlamsal ve söylem boyutlarında incelendiğinde seçilen kısa öykünün özgün materyal olması sebebi ile hiçbir düzenleme ya da uyarlama yapılmadan doğrudan dil öğretimi sürecine dâhil edilmesinin uygun olmadığı sonucuna ulaşılmıştır.
Complete acquisition in the heritage language: Evidence from indefiniteness in Turkish
Authors: YILMAZ Gülsen , SAUERMANN Antje
Published: April 2023

This study investigates whether adult Turkish heritage speakers are able to refer to entities in discourse as required by semantic contexts. The focus is on the contrasting properties of Turkish (L1) and German (L2) with respect to semantics of indefiniteness, i.e., specificity and partitivity. Turkish morphologically distinguishes between specific/nonspecific and partitive/nonpartitive contexts on the indefinite direct object while German does not. We hypothesized that the Turkish heritage speakers would overgeneralize the unmarked form (bir noun) since this is the default form used in German regardless of the context and also acceptable in all contexts in Turkish. We further hypothesized that, if they ever opt for the case marked form (bir noun+acc), they would also do so incorrectly in nonpartitive and nonspecific contexts. Turkish heritage speakers living in Germany (n= 35) could dissociate semantic contexts and made similar preferences to those of monolingual native speakers of Turkish (n= 30). Our findings suggest that native language (L1) can develop despite early onset of the L2 and be maintained on a par with monolingual norms despite the presence of competing structures in the L2. We will discuss how insights from heritage language development can contribute to discussions about the bilingual’s ability in L1; and limits and possibilities of bilingualism.
Birinci Dünya Savaşı Alman kartpostallarında Osmanlı/Türk imgesi
Authors: ŞİMŞEK Selim
Published: April 2023

Siyasi ve askeri alanda yaşanan büyük çatışmaları ile 20. yüzyıl dünyanın kaderinin ve çehresinin en çok değiştiği dönemlerden biri olmuştur. Bilim ve tekniğin her alanda eşi görülmemiş bir hızla dünyanın bilindik yüzünü bu denli çabuk değiştirmesi ülkeler arasında siyasi gerilimlerin ve büyük kitlesel çekişmelerin yaşanmasına yol açmıştır. Bunların ilk büyük örneği 1. Dünya Savaşı ile su yüzüne çıkmıştır. Savaş koşulları kimi zaman eski dostu düşman ederken kimi zaman da yeni dostluklar ortaya çıkarmıştır. Bunun bir örneği Alman ve Avusturya-Macaristan İmparatorlukları ile Osmanlı Devleti arasındaki ilişkide görülür. Osmanlı Devleti’nin parlak dönemlerinde etki alanını hızla genişletip Avrupa’yı sürekli tehdit eder bir noktaya yükselmesi Avrupa’daki toplulukların kolektif hafızasında Türk’e dair neredeyse kemikleşmiş olumsuz bir imge oluşmasına sebep olmuştur. Savaş sebebiyle tesis edilen silah kardeşliği (Waffenbruderschaft) ile cephede omuz omuza savaşmaya başlayan bu uluslar, askerlerine ve halklarına haklı bir mücadelenin verildiği izlenimini vermek, maneviyatı, savaşın sonucuna dair umutları ve heyecanı canlı tutmak ve bu silah arkadaşlığını cephe gerisine de taşımak için çok yönlü propaganda araçlarına başvurmuşlardır. Bu bağlamda, bu makale imgebilimin verilerini kullanarak, özellikle Alman İmparatorluğu tarafından propaganda amacıyla kullanılan kartpostallar üzerinden, zihinlerde kök salmış Osmanlı/Türk imajının görsel/grafik araçlar ve çeşitli semboller, edebi metin parçaları ve mitolojik ögeler ile nasıl yeniden kurgulanmaya çalışıldığını inceler. Sonuç olarak, yeni sunulan Osmanlı/Türk imgesinin tarihsel bağlarından kopuk ve büyük oranda kurgusal bir karakter taşıdığını iddia eder.
Coğrafi bilgi sistemleri ve çok kriterli karar verme yöntemleri: Hibrit çözüm yaklaşımı ile Siirt örneği
Authors: YILDIZ Ertuğrul , ER Fikret
Published: April 2023

Hibrit çözüm yaklaşımı olarak sunulan yöntemde coğrafi bilgi sistemlerinin sunduğu çözüm kümesinin ek araştırmalar ile en uygun yer seçimine mecbur bırakmasına kolaylık sağlamak amacındadır. Bu kolaylığı çok kriterli karar verme yöntemleri ile sağlamaya çalışmaktadır. Yaklaşımın bir uygulamasını içeren bu çalışmada, güneş enerjisi santrali kurulum yeri seçimi problemi ele alınmıştır. Bu problemin çözümü için gerçek hayat verileri ilgili kurumlardan elde edilerek coğrafi bilgi sistemleri analizleri ArcGIS yazılımında “Overlay Analysis” analiz aracı ile gerçekleştirilmiştir. Çok kriterli karar verme yöntemi olarak seçilen PROMETHEE yöntemi RStudio yazılımının "promethee123" paketi ile gerçekleştirilmiştir. Uygulama sonucunda elde edilen sonuçlar bir kurulum yeri seçimi için, işletme olarak kurulumu ve sürdürülebilirliği için öncelik sıralaması sunmaktadır. Sunulan hibrit çözüm yaklaşımı literatürdeki iki adımlı çözüm arayışının veri kaybını en aza indirerek daha bütüncül bir yaklaşım sunmaktadır.
A Study on the Effect of Periodic Auditor Designation on Audit Quality
Authors:   Korea Accounting Information Association, Mun Tae-Hyoung , Lee Jang-Soon
Published: April 2023

[Purpose] This study’s purpose is to verify how the periodic auditor designation system of the newly implemented periodic auditor designation affects audit quality.
[Methodology] Hypotheses were established by reviewing previous studies, and 493 samples from 2019 were selected for KOSPI－listed companies in Korea. The quality of accruals (McNichols, 2002) was used as the dependent variable, and the effect of whether or not the firm was designated as a periodic auditor and whether the auditor was part of the Big 4 was empirically analyzed.
[Findings] As a result of the analysis and correlation analysis, a statistically significant difference was confirmed in the quality of accrual of the dependent variable and the independent variable auditor designation (PA) was found to be insignificant. We could not confirm the difference in audit quality according to the Big 4 auditors. However, a significant difference was only confirmed in ROA and loss in the control variables.
[Implications] This study has significance in that it is a study of the effect of audit quality and the selection of periodic auditor designation companies introduced in 2019 using empirical data. However, since the periodic auditor designation system, which is the main subject of this study, was first implemented in 2019, not much related data has been accumulated, so there are limitations in the analysis of related studies.
PHOTOBIOMODULATION IN BREAST CANCER RADIODERMATITIS: PHOTODERMIS, A DOUBLEBLIND RANDOMIZED CONTROLLED TRIAL (NCT04059809)
Authors: Sgrott Francine Fischer , Baiocchi Jaqueline Munaretto Tim , Baiocchi Neto Glauco , Rech Pamela Cabral Finato , Cruz Anderson da , Ruzza Filho Omar Sulivan , Sapienza Lucas
Published: April 2023

Objective: The aim of this study was to evaluate the impact of photobiomodulation (PBM) in reducing the prevalence of radiodermatitis in breast cancer. Methods: A randomized, double-blind controlled trial was carried out and included women who underwent conservative surgery or mastectomy and were treated with 3D radiotherapy. Patients were randomly assigned (1:1) to receive usual skin care ± red PBM (660 nm) with an energy of 3 joules per point every 2 cm across the breast for 10 min. The degree of radiodermatitis was blindly evaluated by two professionals every 5 days from D5 to D30 of adjuvant radiotherapy. The control group had the PBM device positioned but was not turned on. The device was positioned on top of the operated breast (plastron). Axillary, inframammary, and supraclavicular regions were excluded from the PBM device template. Results: In all, 48 women were included in the study (26 women in the PBM group and 22 in the control group). The median age was 51.5 years (range 29–78), and the median total radiation dose was 50.4 Gy (range 42–55). The clinical and pathological variables did not differ between groups. A total of 16 (33.3%) cases had radiodermatitis in the breast plastron and 42 (87.5%) outside the breast plastron area. Radiodermatitis in the breast plastron was significantly lower in the PBM group compared to that in the control group [11.5% vs. 59.1%; hazard ratio (HR) 0.090 (95%CI 0.021–0.39); p=0.001]. However, there was no difference in radiodermatitis rates outside the breast area (not involved with PBM) for the PBM group compared to that in the control group [88.5% vs. 86.4%; HR 1.21 (95%CI 0.21–6.7); p=0.82]. Additionally, 2 (7.7%) cases in the PBM group and 12 (54.5%) cases in the control group had radiodermatitis in both breast and non-breast regions [HR 0.069 (95%CI 0.013–0.36); p=0.002]. Conclusion: Our results suggest that PBM in women with breast cancer treated with adjuvant radiation significantly reduces the risk of radiodermatitis.
Peran Orang Tua dalam Mengurangi Dampak Negatif Gadget Pada Anak
Authors: Febriani Indah , Sumardi Lalu , Hadisaputra Saprizal , Muhaimi Lalu
Published: April 2023

Gadget merupakan sesuatu yang bisa dibilang saat ini sudah tidak bisa lagi dipisahkan dari kehidupan manusia, bahkan perkembangan gadget sudah tidak lagi memandang usia baik usia anak-anak, remaja, dewasa, sampai orang tua sekalipun semua sudah dipengaruhi oleh gadget. Penelitian ini memiliki bertujuan untuk mendeskripsikan peran orang tua dalam mengurangi dampak gadget terutama pada hasil belajar anak usia dibawah 10 tahun. Penelitian ini termasuk ke dalam penelitian kualitatif dengan jenis studi kasus. Sumber data dari penelitian ini yaitu orang tua dan anak usia dibawah 10 tahun. Metode pengumpulan data yang digunakan di dalam penelitian ini menggunakan metode observasi (pengamatan) dan wawancara.  Teknik analisis data yang digunakan adalah teknik analisis data model interaktif yang dikembangkan Miles, Huberman, dan Saldana yang mencakup tiga tahapan yaitu; kondensasi data, penyajian data, dan penarikan kesimpulan.  Hasil dari penelitian ini yaitu dapat diketahui bahwa terdapat 5 upaya orang tua dalam mengurangi dampak gadget pada anak usia dibawah 10 tahun yaitu; (1) Mengajarkan anak untuk memperhatikan waktu dalam menggunakan gadget dengan membuat aturan waktu atau jadwal dalam menggunakan gadget; (2) menyediakan berbagai jenis permainan di dalam gadget yang  bisa digunakan sebagai sarana pembelajaran bagi anak; (3) orang tua memberikan kesempatan kepada anak untuk bercerita mengenai hal apa saja yang telah dilakukan; (4) orang tua memberikan kesempatan anak untuk mencoba permainan tradisional dengan teman sebayanya di lingkungan sekitar;  (5) orang tua tidak menggunakan gadget ketika sang anak berada di sampingnya dan menggunakan gadget seperlunya saja. Berdasarkan temuan tersebut maka bisa disimpulkan bahwa peran keluarga terutama seorang orang tua sangatlah penting dalam mengatasi dan mencegah dampak negatif penggunaan gadget pada anak karena keluarga merupakan sekolah dan tempat belajar pertama bagi seorang anak.
PANORAMA DO ESTADO NUTRICIONAL DE PACIENTES ADULTOS E IDOSOS PORTADORES DE CARDIOPATIA CONGÊNITA: ESTUDO CONGEN
Authors:   Instituto Dante Pazzanese de Cardiologia,, Gonçalves de Borba Lenita , Ferreira Ribeiro Caroline ,   Instituto Dante Pazzanese de Cardiologia,, Lorenzon Warschauer Gabriela ,   Instituto Dante Pazzanese de Cardiologia,, da Silva Azevedo Gustavo ,   Instituto Dante Pazzanese de Cardiologia,, Cardoso Pimentel Mota Isabela ,   Instituto Dante Pazzanese de Cardiologia,, Louise Silva Isabella ,   Instituto Dante Pazzanese de Cardiologia,, dos Santos Maria José ,   Instituto Dante Pazzanese de Cardiologia,, Moreira Mendes Natalia ,   Instituto Dante Pazzanese de Cardiologia,, Gonçalves Plata Regina ,   Instituto Dante Pazzanese de Cardiologia,, Gonçalves Plata Victor Tadeu ,   Universidade de São Paulo,São Paulo,
Published: April 2023

As cardiopatias congênitas (CC) são malformações no coração que levam a alterações estruturais ou circulatórias, comprometendo seu funcionamento. São responsáveis por 0.8–1.2% de todos os defeitos congênitos e têm uma prevalência de cerca de 5,8 por 1.000 pessoas. Um bom panorama nutricional é essencial para evitar um mal prognóstico no tratamento clínico e cirúrgico. Caracterizar a prevalência do estado nutricional (EN) e correlacionar tempo de internação com EN em pacientes adultos e idosos portadores de CC. O desenho do estudo foi retrospectivo, descritivo e analítico. Foram identificados o índice de massa corporal (IMC) e a medida de circunferência do braço (CB) de pacientes portadores de CC provenientes de banco de dados do Setor de Nutrição de um hospital especializado em cardiologia referentes ao período de 2016 a 2022 em razão do tempo de permanência hospitalar. O estudo foi realizado com 381 pacientes. O sexo feminino correspondeu a 66,15%, com idades entre 18 e 87 anos (média 37,7). O tempo médio de internação foi de 12,5 dias. A CB foi mais sensível para o diagnóstico de desnutrição. A desnutrição na 1ª semana teve a prevalência de 14,50% pelo IMC e, na 6ª semana, de 41,70%. Com relação à CB, a prevalência foi de 36,70% e 50,00% respectivamente. A prevalência do EN foi diferente quando se comparou IMC com CB. O aumento progressivo da desnutrição no decorrer do processo de internação demonstrou que quanto maior o tempo de internação, maior a sua prevalência
PECULIARITIES OF THE FORMATION AND IMPLEMENTATION OF THE SYSTEM OF ENSURING FINANCIAL AND ECONOMIC SECURITY OF INDUSTRIAL ENTERPRISES UNDER THE CONDITION OF VARIABILITY OF THE MARKET ENVIRONMENT
Authors:   Zaporizhzhia National University, Kutsenko Oleksandr
Published: April 2023

It was determined that in the conditions of the variability of external and internal environment factors, the appearance of threats and risks, there is a need to implement management tools for ensuring financial and economic security at enterprises, which will allow timely response to them, form measures to neutralize the impact in order to increase the level of financial and economic security, ensuring the stability of functioning. It was established that the main management tools are the system, mechanism, and strategy for ensuring financial and economic security. The existing approaches to the formation of a system of ensuring financial and economic security have been studied and the absence of a single comprehensive approach has been established. A management system for ensuring the financial and economic security of the enterprise has been formed based on the use of systemic, innovative, informational approaches and is based on components and stages. The implementation of the management system for ensuring the financial and economic security of the enterprise will allow timely identification, research, analysis of factors of the external and internal environment, threats and risks, and adaptation to their influence. This management system provides for the use of information technology in order to automate its work, as well as to improve the work of the management mechanism. It was found that the use of the management system will ensure the effectiveness of the mechanism for further increasing the level of financial and economic security of the enterprise, stabilization of the financial condition, efficiency of economic activity, and determination of development directions in the long term. It was found that the observance of systemic, innovative, informational approaches within the management system guarantees the coherence of its work, the establishment of interaction between all management tools, the implementation of innovative approaches, the development of sound solutions, the use of information technologies for work automation.
DIGITAL MARKETING STRATEGIES OF NON-PROFIT ORGANIZATIONS
Authors:   Kyiv National University of Technologies and Design, Shikovets Catherine , Kvita Halyna ,   Kyiv National University of Technologies and Design, Bebko Svitlana ,   Kyiv National University of Technologies and Design
Published: April 2023

The scientific paper defines the essence of the formation of digital marketing strategies of non-profit organizations. The concept of non-profit organizations and determinants of their development are considered. A general description and assessment of the development of the marketing activity of the Charitable Foundation "Patients of Ukraine" is provided. The Digital marketing strategy of the Charitable Fund "Patients of Ukraine" was formed. The shortcomings of the existing marketing strategy, problems in the use of digital marketing tools by the "Patients of Ukraine" foundation were identified. The external and internal positioning of the organization was studied, and a target audience portrait was drawn up. The main elements of the marketing strategy, which will be used in the further activities of the foundation, have been developed. The main goals of the Digital marketing strategy were determined: increasing the number of the audience, "rejuvenating" the audience, increasing coverage, creating the "Patient of Ukraine" brand, creating a community of patients ready to defend their rights to treatment. Annual and long-term marketing goals and a plan for their implementation were formed, a marketing mix was developed, and non-profit products of the marketing mix were analyzed for the presence of a need for them in society, as well as an analysis of the effectiveness and economic efficiency of the proposed marketing strategy was carried out.
THEORETICAL APPROACHES TO THE DEFINITION OF THE ROLE, ESSENCE AND FUNCTIONS OF AN ENTREPRENEURSHIP IN THE MODERN TURBULENT ECONOMY
Authors:   Taras Shevchenko National University of Kyiv, Pashchuk Lidiia
Published: April 2023

The current paper considers the major theoretical approaches to the formation of the modern concept of entrepreneurship. Taking into account the growing importance of entrepreneurship for the Ukrainian economy which even increased during the full-scale war, both Ukrainian sources and sources from other countries were analyzed to identify the difference between the meanings of the terms “entrepreneurship” and “business”. The historical background and major features of both meanings were identified, which enabled the author to conclude that it is appropriate to use the term"entrepreneurship" when it comes to small and medium-sized economicentities. Instead, the term "business" should be used to refer to theinfrastructure, organization, and management of business activities at all levels. Also, the approaches to the concepts of "entrepreneur" and "entrepreneurship" in the works of various economic schools representatives were considered, thereof physiocrats, marginalists, the Austrian school, the neo-Austrian school of economic liberalism, and neoclassicists. The paper also represents the generalized criteria for the classification of enterprises. Keeping in mind the significant impact of entrepreneurship in various spheres of society the author summarized the functions of enterprises according to the triple bottom line concept.
ALIRAN KALAM SALAFIYAH: Studi atas Perkembangan Pemikirannya
Authors: Miolo Darwin Agung Septian , Arif Muhammad
Published: April 2023

Artikel ini bertujuan untuk mengungkap bagaimana aliran kalam salafiyah dan bagaimana perkembangan pemikirannya. Metode yang digunakan adalah metode analisis kualitatif deskriptif. Hasil kajian dan pembahasan  menunjukkan bahwa aliran kalam salafiyah mempunyai beberapa karakteristik sebagaimana dikemukakan oleh Ibrahim Madzkur yaitu: pertama, mereka lebih mendahulukan riwayat (naqli) dari pada dirayah (aqli); kedua, dalam persoalan pokok-pokok agama dan persoalan cabang-cabang agama hanya bertolak dari penjelasan al-Kitab dan as-Sunnah; ketiga, mereka mengimani Allah tanpa perenungan lebih lanjut (Dzat Allah) dan tidak mempunyai paham anthromophisme (menyerupakan Allah dengan makhluk); keempat, mengartikan ayat-ayat al-Qur’an sesuai dengan makna lahirnya dan tidak berupaya untuk mentakwilnya. Ibn Taimiyah mengemukakan bahwa kaum salaf adalah mereka mempunyai pemikiran bahwa tidak ada jalan untuk mengetahui akidah, hukum, dan apa yang keduanya ada hubungan dengannya, tidak lain hanya berpedoman pada al-Qur’an dan Hadis. Kaum Salaf menerima semua keterangan yang ada dalam al-Qur’an dan Hadis. Menolak berarti melepas tali agama. Akal tidak mempunyai kekuasaan untuk mentakwilkan, menafsirkan, atau menghukumi al-Qur’an. Akal hanya mampu membenarkan, mentaati, dan menerangkan pendekatan antara dalil akal (kontekstual), dengan dalil al-Qur’an dan Hadis (tekstual) dengan tidak ada perbedaan antara dalil akal dengan dalil al-Qur’an dan Hadis. Akal berkedudukan sebagai saksi bukan hakim, sebagai penetap dan penguat bukan penentang, sebagai penjelas dari dalil yang terkandung dalam al-Qur’an. Kaum Salaf selalu menjadikan akal berada di belakang al-Qur’an dan Hadis.
Kebebasan Manusia Khudi (Ego/Diri) Muhammad Iqbal dalam Perspektif Kebebasan Whitehead
Authors: Wibawa Nazar Husain Hadi Pranata
Published: April 2023

Artikel ini membahas tentang kebebasan manusia. Artikel ini ingin menemukan kebebasan manusia menurut Muhamaad Iqbal sebagai objek material dan Whitehead sebagai objek formal. Penelitian ini merupakan studi pustaka. Data dikumpulkan melalui inventarisasi data, kemudian dianalisis dan diinterpretasikan. Hasil penelitian menunjukkan Diri bersifat individual, namun ke-individualitas-an diri/ego tidak berarti menjadikannya egoistik dan terisolir. Setiap ego bersama dengan ego-ego lainnya terikat dalam relasi simbiosis mutualistik, karena ego hidup dalam jejaring organisasional, dan ego sendiri pada level kediriannya bersifat holistik.  Setiap keegoan pribadi dapat diakses oleh ego ego yang lain dengan istilah simbiosis mualistik. Kehendak pribadi terbuka dengan ego atau kehendak orang lain untuk mencipkan masyarakat yang terbuka. Whitehead memperinci kehendak  itu tidak sama dengan tindakan praktis, karena kehendak mempunyai superiotitas sendiri dan sebaliknya kehendak tidak dapat disamakan pengetahuan teoritis,  karena kita bias melihat gejala-gelaja tegangan yang sering muncul dan sulit didamaikan antara keduanya. Kehendak harus diletakkan pada tindakan praktis dan pengetahuan teoritis.
Konsep Negara dalam Fiqih Siyasah
Authors: Fitriyani  , Basir Abd , Fansyuri Abdul Rouf
Published: April 2023

The concept of the state and government is an ijtihad that reflects the exploration of rational speculative thought in order to find an intellectual basis for the function and role of the state and government as an instrumental factor for the fulfillment of the interests and welfare of the people both physically and mentally. The state, in terminology, is defined as the highest organization among a group of people who have the aspiration to unite, live in a certain area and have a sovereign government. Fiqh siyasah as one aspect of Islamic law that discusses the regulation and management of human life in the state in order to achieve the benefit of human itself regardless of the reign after the death of the Prophet Muhammad SAW. Although in the Qur'an there is not a single argument that explicitly commands or obliges Muslims to establish a state. Moreover, even the term state (Daula) is never mentioned in the Qur'an, however, the basic elements in society, nation and state, can be found in it. Some of the main principles include: Deliberation, Justice, Equality.
Pluralisme dan Kerukunan Umat Beragama di Kabupaten Alor Nusa Tenggara Timur Perspektif Maqashid Al-Ummah
Authors: Qodim Husnul , Darwis Rizal
Published: April 2023

Keharmonisan dalam sebuah masyarakat merupakan urgensi dan dambaan setiap manusia. terlebih lagi di tengah-tengah kemajemukan agama pada masyarakat Indonesia. Di tengah kemajemukan tersebut potensi konflik bisa saja terjadi. Penelitian ini bertujuan menganalisis pluralisme dan kerukunan umat beragama di Kabupaten Alor Nusa Tenggara Timur. Jenis penelitian ini adalah kepustakaan dengan sumber data primer berasal dari buku, artikel, dan penelitian-penelitian terkait pluralisme, agama, dan kerukunan umat, khususnya terkait masyarakat Kabupaten Alor. Data yang dikumpulkan diolah dan dianalisis dengan deskriptif kualitatif. Hasil penelitian menunjukkan masyarakat Kabupaten Alor senantiasa menjaga keharmonisan terhadap adanya perbedaan-perbedaan yang hidup dalam masyarakat. Penghargaan terhadap kearifan lokal masyarakat Alor juga berperan penting. Di sisi lain peran pemerintah setempat merupakan pilar yang penting yang dapat mengawal pluralisme dan terciptanya kerukunan antar umat beragama yang berbeda-beda kepercayaan. Dialog dan kerjasama yang dilakukan pemerintah bersama masyarakat Alor memberi dampak positif. Adanya sikap toleransi antarumat beragama yang telah dilakukan masyarakat Alor merupakan bentuk kemaslahatan umat (maqashid al-ummah) dalam konteks hukum Islam.
MENJAGA TRADISI WALISONGO:
Authors: Muhajarah Kurnia
Published: April 2023

Abstract: The visions of some groups about nationality, diversity and local traditions always confront each other as if they are contradictory and impossible to reconcile. The concept of citizenship does not conform to Islamic teachings, especially to local traditions, because the regulation of human life is not in the hands of the national state, but in the hands of the Islamic state. This article aims to explore the urgency of Islamic moderation in higher education to strengthen national, religious and local traditions. This study uses a descriptive qualitative method and a literature review. Using this method, it is expected that researchers can comprehensively analyze the importance of Islamic moderation in higher education using national, religious and local traditions. These triangles are interconnected and mutually reinforcing. This is the reality of human civilization, recognized in Islamic teachings as part of God's will in creating heterogeneous people. Students should be taught Islamic moderation so that their religious views and attitudes reflect national values. Based on the results of the investigation, it was found that many things were national, religious and local traditions that do not conflict with Islam; and the need to integrate the subject of Islam and religious moderation with other courses.
Miten suomen ja ruotsin opettajat käyttäisivät puheen automaattiseen arviointiin kehitettyä työkalua?
Authors: Von Zansen Anna , Heijala Maikki
Published: April 2023

In this study, we interviewed four language teachers in order to investigate their perceptions of an automated tool developed for assessing Finnish and Swedish learners’ speech. We showed the first version of the Moodle plugin developed by the DigiTala research project to the teachers. In this version, after recording a speech sample, the system provides analytic and holistic feedback to the learner. The automated feedback was developed based on the rating criteria that human raters have used earlier in the project. The data consist of four semi-structured individual interviews conducted in Zoom. The interviews were transcribed and analysed using content analysis. We found that automated feedback has significant implication areas in language learning and teaching. Teachers found the feedback statements understandable and useful, even though they do not cover all dimensions relevant for the speaking construct. The results will benefit those working on automated assessment of oral language skills.