bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PERPUTARAN PERSEDIAAN DAN PERTUMBUHAN PENJUALAN TERHADAP PROFITABILITAS PADA TOKO-TOKO DI SEKITAR PASAR HORAS PEMATANG SIANTAR
Authors: Siboro Danri , Sianipar Victor H , Saragi Dame Ria Rananta
Published: February 2023

Shops are essential because they can create business fields to support daily economic needs. Inventory Turnover is a crucial thing in trading business operations. This study aims to determine whether inventory turnover and sales growth affect the profitability of shops around the Horas Market Pematang Siantar. This study uses primary data. Questionnaires were distributed to business actors around the Horas Market Pematangsiantar. The respondents in this study amounted to 32 stores. This study used a quantitative approach and processed data from questionnaires transformed through a Likert scale. At the same time, the analysis used in this study is a simple linear regression with a significant level of 5%. There is a positive influence between inventory and sales at shops around the Horas Market Pematangsiantar, where the t.count value is 2.672 > table is 1.69389—evidenced by the coefficient of determination R Square of 19.2%. In addition, there is a positive influence between inventory and profitability in shops around the Horas Market Pematangsiantar, where the t.count value is 2.245 > table is 1.69389. Evidenced by the coefficient of determination R Square of 14.4%.

Key word: Inventory, Sales Growth, And Profitability
Optimization of Total Cost of Production for a Mixed Make-To-Order (MTO) and Make-To-Stock (MTS) Production System with Lot Sizing for the RMG Industry in Bangladesh
Authors: Hosen Md. Imran , Mridha Jaglul Hoque , Musfiq Masum , Hossen Md. Shahin , Uddin Mohammed Raihan , Uz-Zaman Md. Sakib , Mahmud Shoaib , Hossain Arif
Published: February 2023

This paper contains a production and inventory planning model with lot sizing in an RMG factory. This model is an example of mixed integer linear programming. The primary goal of this approach, which combines the make-to-order (MTO) and make-to-stock (MTS) production methods are to simultaneously satisfy existing customer orders and new customer orders in order to reduce the total cost. Here, make-to-order (MTO) and make-to-stock (MTS) production systems are becoming more and more common since they allow businesses to increase revenues while managing expenses by maintaining a positive cash flow. For mixed contexts where demand is cyclical but predictable, and the model stores the predicted data and fresh forthcoming orders.
Penyuluhan Strategi Pengentasan Kemiskinan Berbasis Masyarakat di Desa Simpar Kabupaten Batang
Authors: Setiawan Hendy , Choirunnisa Choirunnisa
Published: February 2023

Poverty is a problem that continues to hit an area that is always sustainable. It seems that the various policies and programs that have been launched by the Central Government have not been sufficiently optimal and have no significance in creating the welfare of its citizens. Therefore, under these conditions, poverty becomes a very complex problem. It is on the basis of this complexity that the government cannot complete the work itself, so cooperation and collaboration between various parties becomes important. Simpar Village, Bandar Subdistrict, Batang Regency is one of the villages based on data from the Batang Regency Government Planning, Research and Development Agency as a village with poor status. Therefore, seeing this situation, the researchers carried out community service by counseling about poverty alleviation strategies with the modality of community strength itself. Through this counseling, the people of Simpar Village will be increasingly aware of how strong the power of local communities can reduce poverty levels in an area. This service method uses a participatory counseling approach that invites related village officials, community leaders, Village Community Institutions, and also members of the village community. The technique is through opening, filling in the material, forming a Forum Group Discussion, and asking questions in accordance with the presentation of the material. The results showed that the people of Simpar Village had a participative attitude in counseling activities, where discussions and questions and answers went well. It is hoped that with this counseling all components of the Simpar Village community will understand and apply how to overcome poverty they face with the strength of the community itself based on this understanding.
Prevention of the Development of Endometriosis in Patients with Dysmenorrhea Using Combined Hormonal Contraceptives Containing Ethinyl Estradiol and Desogestrel, with an Assessment of Changes in the Hemostasis System
Authors: Гутикова Л.В. , Павловская М.А.
Published: February 2023

В статье проанализировано влияние микро- и низкодозированных комбинированных гормональных контрацептивов, содержащих этинилэстрадиол и дезогестрел, на показатели системы гемостаза у женщин, страдающих дисменореей. Установлено, что применение указанных препаратов у пациенток с дисменореей не вызывало клинически значимых изменений системы гемостаза. При этом микродозированные комбинированныегормональные контрацептивы обладают меньшим тромбофилическим влиянием, чем низкодозированные.

The article analyzes the effect of micro- and low-dose combined hormonal contraceptives containing ethinylestradiol and desogestrel on the parameters of the hemostasis system in women with dysmenorrhea. It was found that the use of these drugs in patients with dysmenorrhea did not cause clinically significant changes in the hemostasis system. At the same time, microdose combined hormonal contraceptives have a lesser thrombophilic effect than low-dose ones.
The Problem of Aspirin Resistance in Obstetrics
Authors: Ганчар Е.П. , Кажина М.В. , Гутикова Л.В. , Зуховицкая Е.В.
Published: February 2023

Цель. Изучить частоту встречаемости резистентности к аспирину у женщин группы риска по развитию ПЭ, фетоплацентарной недостаточности, тромбоэмболических осложнений; выявить факторы риска аспиринорезистентности. Материалы и методы. Обследованы 62 беременные с риском развития ПЭ, фетоплацентарной недостаточности, тромбоэмболических осложнений в сроке 13–14 недель. Исследование агрегации выполнялось на автоматическом анализаторе функции тромбоцитов Multiplat (ROCHE Diagnostics GmbH, Германия). Аспиринорезистентность фиксировалась по данным ASPI-test при значении AUC выше 30 U. Результаты. Аспиринорезистентность выявлена в 19 (30,6%) случаях (ASPI-test – 56,5 [50,5–67,8] U), в 43 (69,4%) случаях пациенты были чувствительны к ацетилсалициловой кислоте (ASPI-test – 26 [24,5–28,2] U). Ожирение, дислипидемия являются факторами риска аспиринорезистентности. Выявлена положительная корреляционная связь между показателем аспиринорезистентности (ASPI-test, U) и уровнем липопротеидов низкой плотности (r=0,43), триглицеридов (r=0,47), холестерина (r=–0,39), отрицательная корреляционная связь с уровнем липопротеидов высокой плотности (r=–0,41). Заключение. Полученные результаты требуют персонализированного подхода в назначении АСК с целью эффективной профилактики гестационных осложнений.

Purpose. To study the incidence of aspirin resistance in women at risk for the development of PE, fetoplacental insufficiency, thromboembolic complications; identify risk factors for aspirin resistance. Materials and methods. 62 pregnant women with the risk of developing PE, fetoplacental insufficiency, thromboembolic complications in the period of 13–14 weeks were examined. The aggregation study was performed on an automatic platelet function analyzer Multiplat (ROCHE Diagnostics GmbH, Germany). Aspirin resistance was recorded according to the ASPI-test at an AUC value above 30 U. Results. Aspirin resistance was detected in 19 (30.6%) cases (ASPI-test – 56.5 [50.5–67.8] U), in 43 (69.4%) cases, patients were sensitive to acetylsalicylic acid (ASPI-test – 26 [24.5– 28.2] U). Obesity, dyslipidemia are risk factors for aspirin resistance. A positive correlation was found between the aspirin resistance index (ASPI-test, U) and the level of low-density lipoproteins (r=0.43), triglycerides (r=0.47), cholesterol (r=–0.39), a negative correlation with the level of high density lipoproteins (r=–0.41). Conclusion. The results obtained require a personalized approach in the appointment of ASA in order to effectively prevent gestational complications.
Consensus Statements on Preinvasive Vulvar Lesions of the European Society of Gynecological Oncology, the International Society for the Study of Vulvovaginal Diseases, the European College for the Study of Vulvar Diseases, and the European Colposcopy Federation (Review)
Authors: Матылевич О.П. , Павлюковский И.В. , Надточеева Е.П. , Доломанова Е.В. , Мавричев С.А.
Published: February 2023

C целью улучшения качества лечения и ведения пациентов с плоскоклеточной интраэпителиальной неоплазией вульвы (VIN), болезнью Педжета и меланомой in situ вульвы Европейское общество гинекологической онкологии (ESGO), Междуна- родное общество по изучению вульвовагинальных заболеваний (ISSVD), Европейский колледж по изучению заболеваний вульвы (ECSVD) и Европейская федерация кольпоскопии (EFC) разработали совместные консенсусные заявления. В них указано, что при дифференцированной интраэпителиальной неоплазии вульвы (dVIN) всегда следует применять эксцизионную процедуру. При плоскоклеточном интраэпителиальном поражении вульвы высокой степени (VHSIL) можно использовать эксцизионные и абляционные процедуры, а также медикаментозные варианты лечения (имиквимод, цидофовир). При болезни Педжета вульвы предпочтение отдается подходу с использованием имиквимода. В случае применения хирургического вмешательства рекомендуемый отступ от границ поражения должен составлять 2 см. При меланоме in situ рекомендуется широкое локальное иссечение со свободным хирургическим краем около 1 см. Последующее наблюдение должно модулироваться в соответствии с возможным риском развития рецидива заболевания в зависимости от типа поражения, возраста пациентки и иммунологических состояний, а также других сопутствующих поражений нижних отделов половых путей.

To improve the quality of treatment and management of patients with vulvar squamous intraepithelial neoplasia (VIN), Paget’s disease and melanoma in situ of the vulva European Society of Gynecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Diseases (ISSVD), the European College for the Study Vulvar Diseases (ECSVD) and the European Federation of Colposcopy (EFC) have developed joint consensus statements. They state that an excisional procedure should always be used in vulvar differentiated intraepithelial neoplasia (dVIN). For high-grade vulvar squamous intraepithelial lesion (VHSIL), excisional and ablative procedures, as well as medical treatment options (imiquimod, cidofovir), can be used. In Paget’s disease of the vulva, the imiquimod approach is preferred. In the case of surgical intervention, the recommended indentation from the borders of the lesion should be 2.0 cm. For melanoma in situ, a wide local excision with a free surgical margin of about 1.0 cm is recommended. Follow-up should be modulated according to the possible risk of disease recurrence depending on the type of lesion, the patient’s age and immunological conditions, as well as other concomitant lesions of the lower genital tract.
MHT: Recommendations and Their Application
Authors: Теслова О.А. , Кириллова Е.Н. , Недень Л.Ч.
Published: February 2023

В статье представлены современные подходы к диагностике, обследованию и принципам менопаузальной гормональной терапии (МГТ) у женщин с климактерическим синдромом. Менопаузальный период, являясь физиологическим периодом в жизни женщины, часто предопределяет развитие ряда патологических изменений многих органов и систем, о чем должны быть информированы врачи-специалисты разных клинических дисциплин. В статье рассмотрены вопросы возможности профилактики развития сердечно-сосудистых заболеваний и риски тромбоэмболических осложнений, что важно с точки зрения индивидуального междисциплинарного подхода к МГТ.

The article presents modern approaches to the diagnosis, examination and principles of menopausal hormone therapy (MHT) in women with menopausal syndrome. The menopausal period, being a physiological period in a woman’s life, often predetermines the development of a number of pathological changes in many organs and systems, which should be informed by medical specialists in various clinical disciplines. The article deals with the issues of the possibility of preventing the development of cardiovascular diseases and the risks of thromboembolic complications, which is important from the point of view of an individual interdisciplinary approach to MHT.
SEQUÊNCIA DIDÁTICA ESTRUTURADA NOS TRÊS MOMENTOS PEDAGÓGICOS: LEIS DE NEWTON
Authors: GOMES DA SILVA BRUNO
Published: February 2023

When it comes to teaching physics, Newton's laws, there is a common problem of physics textbooks that teachers corroborate with the repetition of this, which is the lack of contextualization of teaching. It is commonplace to approach, for example, a block of mass m, this being approached statically or in motion, but students cannot understand that the studied knowledge is also in their daily lives. They cannot relate school knowledge to everyday knowledge. Physics is a complex language, often new in students' lives and, since the target audience are young and adult students of the EJA modality, from high school, who often have been out of a classroom for up to 30 years, the physics becomes something of maximum complexity. Because it includes mathematics, requires logical reasoning and interpretation of texts, so it becomes a discipline that is not easy for students. The work aims to build a didactic sequence for teaching Newton's laws. The methodology used in the didactic sequence is based on the theory of the Three Pedagogical Moments by Delizoicov and Angotti (1990). The research results are in the course of the work.
Satisfacción al cliente. Caso: Empresa la fabril, Cañar, el Tambo y Suscal, Ecuador
Authors: Tixi-Tacuri Jose Virgilio , Vásquez-Hugo Edgar Santiago
Published: February 2023

La investigación tuvo como objetivo determinar el nivel de satisfacción que tienen los clientes de la organización La Fabril, específicamente en las ciudades de Cañar, El Tambo y Suscal, la investigación fue no experimental, el diseño metodológico fue de tipo transversal transversal con uso de la encuesta SERVPERF (Service Performance) que evalúa la calidad de servicio a través de cinco dimensiones: elementos tangibles, fiabilidad, capacidad de respuesta, seguridad y empatía, los mismos fueron aplicados a 30 supermercados y tiendas de abastos del Cañar, Tambo y Suscal. Los resultados muestran que los factores más relevantes de la satisfacción de los clientes de la empresa La Fabril son Empatía y Seguridad, y la menos valorada es la Fiabilidad de la empresa. Se concluye que la empresa satisface las necesidades de sus clientes, no obstante, requiere integrar estrategias de seguimiento y control a los problemas que se presentan en el proceso de distribución.
Socio-productividad comunal para el desarrollo sustentable
Authors: Bello-Quevedo Williams Jesús , Giménez-Guariguata Maribel José
Published: February 2023

El objetivo principal identificar y analizar las capacidades socio-productivas para ejercer acción transformadora en el marco de la economía comunal para el fortalecimiento de la comuna Robert Serra Creolandia revolucionaria, en el municipio los Taques del Estado Falcón. El diseño de la investigación fue no experimental, tipo de campo y nivel descriptivo. La economía comunal descansa en el esfuerzo y contribución de sus trabajadores, los cuales están llamados a generar un creciente excedente que sustente la inversión de interés comunitario y social. La socioproductividad es la articulación adecuada con los entes responsables del estado en la solución de los problemas, para dar respuesta a la actual crisis económica alimentaria y rescatará las infraestructuras abandonadas, promoviendo la justicia social; el desarrollo de esta investigación permitió aportar conocimientos sobre la gerencia de programas y proyectos socio productivo comunales, área de vital importancia para contribuir con el desarrollo local de su comunidad.
Importancia de la Gestión del Talento Humano para optimar las organizaciones
Authors: Maldonado-Mosquera Damil José
Published: February 2023

Editorial
Formulation of Silver Nanoparticles Liquid Hand Wash with Polyvinyl Alcohol as Stabilizer
Authors: Sutriyo  , Hanandi Sharon , Putri Kurnia Sari Setio , Poetri Okti Nadia , Annisa Syifa , Rahmasari Ratika
Published: February 2023

According to Global Burden of Disease reported on 2019, about 1.53 million deaths caused by infectious diseases such as pneumonia and diarrhea. Triclosan is one of the active ingredient commonly used in antibacterial soap as one way to prevent the spread of infectious disease.. However, bacteria resistance against triclosan has been reported. Silver nanoparticles (AgNP) is an alternative antibacterial that potential to be used in liquid hand wash. However AgNp tend to aggregate during storage, thus stabilizer is needed This study aims to synthesize AgNP, formulate the liquid hand wash contain AgNP with polyvinil alcohol as stabilizer, and evaluate its effectiveness against Escherichia coli, Staphylococcus aureus, and Salmonella thypi. AgNP was prepared using the chemical reduction method between silver nitrate and sodium borohydride, followed by its characterization using UV-Vis spectrophotometer, TEM, PSA, and AAS. The physical characteristic of AgNp-liquid hand wash were also evaluated. Further, the antibacterial activity of AgNP-handwash was evaluated by phenol coefficient method. The peak of UV absorption spectrum of colloidal was found at 404.2 nm indicated the presence of AgNP. Ag content in AgNP colloidal was 38.405 mg/Kg ± 0,008. The spherical shape of AgNP was observed. The AgNP size was 65.1 nm with polydispersity index value of 0.543, and zeta potential value was -22.25 mV. The obtained AgNP-hand wash met the Indonesian standard criteria and was stable for 28 days. The best phenol coefficient value was obtained at formulation with addition of 30% AgNP (0.1 for S. typhi, 0.4 for E. coli, and 0.01 for S. aureus).
Preventive Health Behaviors Pada Caregiver Pasien Lansia Dan Hubungannya Dengan Kepatuhan Pengobatan Di Sulawesi Selatan
Authors: Anggriani A. , Rahmawati Fita , Wahab Izyan Abdul
Published: February 2023

Pasien lanjut usia atau geriatri rentan terhadap berbagai masalah klinis yang timbul akibat proses degeneratif dan berpengaruh dalam menjalankan kegiatan pribadi sehingga membutuhkan bantuan dari orang lain yang disebut caregiver. Seorang caregiver, selain membantu kegiatan pribadi pasien geriatri, juga berperan penuh dalam proses penyembuhan pasien. Hal ini dapat mengakibatkan caregiver akan memiliki beban mental yang harus diperhatikan agar proses caregiving pada pasien lanjut usia dapat berjalan dengan lancar. Penelitian ini dilakukan untuk mengidentifikasi aspek penguasaan emosional individu caregiver serta menelaah perannya dalam proses pengobatan pasien geriatri, terutama pada kepatuhan penggunaan obat. Penelitian ini menggunakan rancangan cross sectional yang melibatkan 131 responden. Pengumpulan data dilakukan melalui wawancara terhadap caregiver pasien usia lanjut yang mendapatkan layanan kesehatan di Puskesmas daerah Sulawesi Selatan. Instrumen kuesioner Pearlin Mastery Score digunakan untuk mengukur penguasaan emosional individu caregiver, dan pill count method untuk mengetahui tingkat kepatuhan pasien. Analisis data menggunakan statistik deskriptif terkait data demografi pasien dan caregiver serta Spearman-rho untuk mengetahui hubungan antar variabel. Hasil analisis menunjukkan angka koefisien korelasi sebesar 0,417** yaitu tingkat hubungan antara variabel penguasaan emosional caregiver terhadap tingkat kepatuhan pasien geriatri adalah sebesar 0,417 atau korelasi sedang dengan hubungan antar variabel searah dan bernilai signifikan (p<0,05). Semakin tinggi tingkat penguasaan emosional caregiver maka semakin tinggi tingkat kepatuhan pasien geriatri.

Kata kunci:  Geriatri, Caregiver, Preventive Health Behaviour, Kepatuhan Penggunaan Obat
A LITERATURE REVIEW OF HERBAL SUNSCREEN’S DOSAGE FORM AND SPF VALUE CLAIM
Authors: Rachmawati Putriana , Sagala Reynelda Juliani , Kambira Pretty Falena Atmanda
Published: February 2023

The Indonesian government recommended sunbathing for 15 to 30 minutes in the morning to deal with the Covid-19 pandemic. Exposure to sunlight will activate the formation of vitamin D, which the body needs for defense against Covid-19 infection. However, excessive sun exposure will cause skin problems, including psoriasis, sarcoidosis, sunburn to skin cancer. One of the protections against sun exposure is the use of sunscreen. Sunscreen protects the skin from UV exposure by two mechanisms, namely, absorbing UV rays or reflecting UV rays. Sunscreen has various dosage forms that are tailored to the needs of consumers. Several dosage forms are preferred because they are easy to use and can be used in groups of children. Sunscreen protection is stated using a photoprotector claim in the form of an SPF value or other claims that support the function of sunscreen. Although SPF has been used worldwide, there are several standard claims for the effectiveness of sunscreens in several countries, such as the broad spectrum and UVA-PA (PA+ to PA++++) claims.
Amikasin: Profil Penggunaan pada Pasien Dewasa Rawat Inap di RSUP Dr.Sardjito Yogyakarta berdasarkan Fungsi Ginjal
Authors: Utami Esti Dyah , Puspitasari Ika , Asdie Rizka Humardewayanti , Lukitaningsih Endang , Dahesihdewi Andaru
Published: February 2023

Latar belakang: Amikasin digunakan untuk infeksi serius gram negatif resisten gentamisin dan tobramisin. Insidensi nefrotoksisitasnya 3-13%, >90% diekskresikan tidak berubah melalui ginjal dan akumulasi dapat terjadi pada disfungsi ginjal.

Tujuan: Mengetahui profil penggunaan amikasin pada pasien dewasa berdasarkan fungsi ginjalnya serta hubungan fungsi ginjal terhadap kondisi keluar RS dan length of stay.

Metode: Penelitian cross-sectional secara retrospektif dengan pengambilan data RM pasien ≥18tahun rawat inap di RSUP Dr. Sardjito tahun 2020 yang diterapi amikasin (total sampling). Karakteristik dan profil penggunaan dianalisis deskriptif. Uji Chi-Square untuk mengetahui perbedaan proporsinya pada pasien ginjal normal dibandingkan gangguan ginjal, serta hubungan fungsi ginjal dengan kondisi KRS dan LOS.     

Hasil: Dari 78 subyek, mayoritas fungsi ginjalnya normal, kondisi KRS tidak membaik, dan LOS 4-63 hari. Mayoritas dari 98 regimen amikasin merupakan terapi empiris, kombinasi antibiotik, rute IV-infus, untuk indikasi sepsis/syok-sepsis+pneumonia; median dosis 14,3mg/kgBB/hari, interval 12jam, dan durasi 5hari. Hasil Chi-Square menunjukkan proporsi CrCl, jenis infeksi, komorbid, interval dan durasi amikasin berbeda signifikan (p<0,05) antara pasien ginjal normal dan gangguan ginjal. Terdapat hubungan signifikan antara fungsi ginjal dengan kondisi KRS (p=0,003, OR=4,58), namun tidak dengan LOS.

Kesimpulan : Fungsi ginjal berasosiasi positif dengan kondisi KRS pasien. Perlu penelitian lanjutan untuk mengevaluasi pendosisan amikasin berdasarkan fungsi ginjal.
Potensi Kurma Sebagai Sumber Nutrasetikal dan Pangan Fungsional
Authors: Gondokesumo Marisca Evalina , Susilowati Retno Wilujeng
Published: February 2023

Buah kurma adalah tanaman buah tertua di dunia yang dibudidayakan sebagai salah satu makanan pokok dari berbagai negara terutama di kawasan Jazirah Arab, Afrika Utara, dan Timur Tengah. Kurma dan produk sampingannya, seperti biji kurma, memiliki nilai gizi dan efek kesehatan. Kurma termasuk pangan kaya akan karbohidrat, serat pangan, protein, mineral dan vitamin B kompleks seperti tiamin (B1), riboflavin (B2), niasin (B3), pantotenat (B5), piridoksin (B6), dan folat (B9). Selain itu, buah serta biji kurma kaya akan fitokimia, seperti fenolat, antosianin, karotenoid, tokoferol, tokotrienol, dan fitosterol. Namun demikian, buah maupun biji kurma belum sepenuhnya dianggap sebagai bahan pangan fungsional yang potensial untuk dikembangkan menjadi pangan yang menjanjikan untuk kesehatan. Beberapa penelitian melaporkan manfaat kesehatan kurma yang diuji secara in-vitro dan in-vivo. Penelitian lebih lanjut akan memberikan informasi yang berharga untuk pemanfaatan potensi buah dan biji kurma sebagai bahan pangan fungsional. Tinjauan ini menyajikan informasi yang komprehensif tentang senyawa bioaktif dan sifat nutrasetikal kurma, serta telaah potensi kurma sebagai bahan pangan fungsional.
Karakterisasi Morfologis dan Molekuler Varietas Kedelai (Glycine max) untuk Identifikasi Bahan Baku Obat Tradisional Indonesia
Authors: Wiradjaja Fuad Soegibudiono , Yunita Oeke
Published: February 2023

Kedelai (Glycine max) mengandung banyak nutrisi dan senyawa aktif berkhasiat obat yang berperan penting dalam mengurangi resiko berbagai jenis kanker, penyakit kardiovaskular, masalah pascamenopause, diabetes, dan beberapa gangguan neurodegeneratif. Beberapa kejadian alergi yang disebabkan oleh protein di dalam kedelai menjadi salah satu pemicu perlunya kontrol kualitas kedelai sebagai bahan baku obat tradisional atau produk herbal. Upaya kontrol kualitas kedelai dilakukan dengan karakterisasi morfologis dan karakterisasi molekuler dengan metode Random Amplified Polymorphic DNA (RAPD). Autentikasi molekuler dengan RAPD lebih dapat membedakan 35 varietas kedelai dibandingkan dengan karakterisasi morfologis.
Cost Analysis Terapi Antidiabetik pada In Patient Diabetes Melitus Tipe 2 di RSU Anwar Medika
Authors: Jalmav Marthy Meliana Ariyanti , Yuniati Hoiriyah Yuniati
Published: February 2023

Diabetes adalah penyakit kronis yang kompleks yang membutuhkan perawatan medis berkelanjutan dengan strategi pengurangan risiko multifaktorial di luar kendali glikemik. Penelitian ini bertujuan untuk mengetahui gambaran biaya langsung medis prespektif Rumah Sakit Umum Anwar Medika pada pasien Diabetes Melitus (DM) tipe 2 yang menggunakan fasilitas Jaminan Kesehatan Nasional (JKN) serta melihat perbedaan antara biaya riil (total biaya langsung medis) dengan tarif INA CBG’s. Penelitian bersifat retrospektif selama 1 tahun kebelakang yaitu periode Januari- Desember 2020. Subjek dari penelitian ini berjumlah 54 pasien. Analisis Mann- Whitney digunakan untuk melihat kesesuaian biaya riil dengan tarif INA-CBG’s. Hasil penelitian ini menunjukkan total biaya riil pada pasien DM tipe 2 JKN di RSU Anwar Medika Periode Januari-Desember 2020 sejumlah Rp.269.807.380 serta terdapat selisih antara biaya riil dengan tarif INA-CBG’s pada kelas 3 sebesar -4,190,371 di mana tarif INA-CBG’s lebih sedikit dibandingkan dengan biaya riil rumah sakit. Hasil pengujian menggunakan metode Mann-Whitney menunjukkan nilai perbedaan yang tidak signifikan antara biaya rill dengan tarif INA-CBG’s. Hasil p=0,458 dimana p>0,05 dikatakan tidak signifikan
PERBEDAAN EFEKTIVITAS EDUKASI BEYOND USE DATE MELALUI BUKU SAKU DAN VIDEO TERHADAP TINGKAT PENGETAHUAN
Authors: Veronica Elsa Ignatia , Arrang Sherly Tandi , Notario Dion
Published: February 2023

Stabilitas sediaan obat sangat penting untuk dijaga karena dapat mempengaruhi mutu, efektivitas, dan keamanan sediaan obat tersebut. Apabila kemasan primer dari suatu sediaan obat dibuka, maka stabilitas sediaan tersebut beresiko mengalami penurunan. Durasi stabilitas suatu sediaan obat dikorelasikan dengan masa kadaluarsa. Masa kadaluarsa sediaan obat yang sudah dibuka dari kemasan aslinya atau setelah diracik atau dicampur dengan sediaan lain dikenal dengan beyond use date (BUD). Penelitian mengenai tingkat pengetahuan masyarakat mengenai BUD masih kurang dan hasil dari beberapa penelitian menunjukkan bahwa masyarakat belum mengetahui dan memahami tentang BUD. Oleh sebab itu, dilakukan penelitian untuk menilai perbedaan efektivitas media edukasi (buku saku dan video) terhadap pengetahuan terkait BUD. Penelitian yang dilakukan merupakan penelitian kuantitatif, dengan design penelitian eksperimental yaitu mengukur pengetahuan responden sebelum (pre-test) dan sesudah (post-test) diberikan edukasi melalui media edukasi berupa buku saku atau video. Pengumpulan data dilakukan menggunakan kuesioner, kemudian dilakukan analisis univariat, bivariat, dan multivariat dengan menggunakan software R. Jumlah responden pada penelitan ini adalah 70 orang, kelompok dibagi menjadi dua yaitu kelompok buku saku (35 orang) dan kelompok video (35 orang). Berdasarkan hasil analisis diperoleh bahwa setelah diberikan edukasi terdapat perubahan terhadap pengetahuan responden. Sebanyak 60% responden kelompok buku saku memiliki pengetahuan yang kurang sebelum diberikan edukasi dan setelah diberi edukasi 74% responden memiliki pengetahuan yang baik (p=0,01). Dalam kelompok video, terjadi peningkatan dalam kelompok responden pengetahuan baik, yaitu sebelum diberikan edukasi jumlahnya 37%, meningkat menjadi 43% setelah diberikan edukasi (p=0,01). Pada analisis regresi diperoleh hasil bahwa media edukasi memiliki pengaruh yang signifikan terhadap pengetahuan responden terkait BUD (p=0,04). Edukasi baik dengan buku saku dan video meningkatkan pengetahuan mengenai BUD, namun video memberikan peningkatan pengetahuan yang lebih baik.
Pengaruh Asuhan Kefarmasian Terhadap Outcome Klinis Dan Kualitas Hidup Pada Pasien Diabetes Melitus Tipe 2
Authors: Khairunnisa  , Rawitri Kiki , Wiryanto  , Wahyuni Sri
Published: February 2023

Peran apoteker dalam asuhan kefarmasian telah terbukti meningkatkan outcome terapi pada pasien diabetes melitus (DM) di berbagai negara. Penelitian ini bertujuan untuk menerapkan asuhan kefarmasian dan mengetahui pengaruhnya terhadap outcome klinis dan kualitas hidup pasien DM tipe 2 di Apotek. Penelitian ini menggunakan metode eksperimental komparatif dengan desain penelitian kohort-studi prospektif sebelum dan setelah intervensi terhadap 38 pasien DM tipe 2 yang memenuhi kriteria inklusi di salah satu Apotek di Kota Medan pada bulan Agustus-Desember 2020. Data outcome klinis meliputi kadar gula darah (KGD) sewaktu dan nilai HbA1c diperoleh dari pemeriksaan langsung pada pasien, dan data kualitas hidup diperoleh menggunakan kuesioner EQ-5D-3L. Data dianalisis menggunakan uji Wilcoxon Signed Rank dan uji Friedman dalam program SPSS V22.0. Hasil penelitian menunjukkan nilai KGD sewaktu rata-rata sebelum intervensi sebesar 278,58 ± 75,27 mg/dl dan setelah intervensi terjadi penurunan menjadi 179,68 ± 14,01 mg/dl (α<0,05), nilai HbA1c 9,021 ± 1,029% menjadi 8,368 ± 1,049% (α<0,05). Terjadi peningkatan secara signifikan indeks kualitas hidup rata-rata sebelum intervensi sebesar 0,849 ± 0,126 dan setelah intervensi menjadi 0,967 ± 0,065 (α<0,05). Berdasarkan hasil penelitian disimpulkan bahwa penerapan asuhan kefarmasian berpengaruh terhadap peningkatan outcome klinis dan kualitas hidup pada pasien DM tipe 2 di Apotek.
LC-MS of Grammatophyllum scriptum (Lindl.)Bl. and Cytoxic Activity Test
Authors: De Fretes Christina , Simaremare Eva , Gunawan Elsye , Agustini Verena , Maulana Yusuf Eka , Fadhilah Nabila Nur
Published: February 2023

Anggrek Macan  (Grammatophyllum scriptum (Lindl.) Bl.) merupakan salah satu tanaman yang digemari di kalangan masyarakat sebagai tanaman hias karena bunganya yang indah. Aggrek macan memiliki senyawa metabolit sekunder alkaloid, flavonoid dan tannin yang dapat digunakan sebagai pengobatan tradisional. Namun, penelitian mengenai Anggrek Macan  di bidang farmakologi masih sangat terbatas. Tujuan penelitian ini adalah mengetahui kandungan senyawa kimia yang terdapat dalam ekstrak herba Anggrek Macan secara LC-MS/MS serta nilai LC₅₀ dan konsentrasi dari ekstrak herba Anggrek Macan  yang paling efektif membunuh larva udang (Artemia salina Leach.). Metode yang digunakan dalam penelitian ini adalah pengambilan sampel dari kebun Anggrek yang ada di Lingkungan FMIPA Universitas Cenderawasih Papua-Indonesia, selanjutnya sampel dibuat dalam bentuk simplisia, diekstraksi dengan etil asetat. Ekstrak selanjutnya dianalisis dengan LC-MS/MS dan dari ekstrak tersebut juga dilakukan uji sitotoksik dengan metode BSLT (Brine Shrimp Lethality Test). Hasil penelitian menunjukkan bahwa Anggrek Macan (Grammatophyllum scriptum (Lindl.) Bl.) mengandung 2′,6′-Dihydroxy-4′-methoxy-dihydrochalcone, Apigenin-7-O-α-L-rhamnose(1→4)-6"-O-acetyl-β-D-glucoside, Kushenol H, Rubrofusarin, 3-Hydroxy baicalein dan Luteolin yang diperoleh dari hasil analisis menggunakan Liquid Chromatography tandem Mass Spectrometry (LC-MS/MS). Ekstrak herba Anggrek Macan   memiliki aktivitas sitotoksik dengan nilai LC₅₀ 150,96 ppm dengan tergolong kurang toksik.
Orientando uma estudante surda
Authors: Porfírio Luciana Cristina
Published: February 2023

Este artigo relata a orientação acadêmica de uma estudante surda em um curso de Pedagogia de uma universidade pública federal, cujo ingresso no ensino superior ocorreu em 2012 e a conclusão em 2019. A produção deste artigo ocorreu a partir da abordagem qualitativa e descritiva com estudo de caso do próprio percurso metodológico utilizado na orientação. A partir da observação direta desta autora e da pesquisa documental, os dados foram coletados considerando os ajustes realizados na condução da orientação, resultando em um Trabalho de Conclusão de Curso produzido por meio do gênero memorial e mediado pela intérprete de Libras. A metodologia envolveu a delimitação de marcadores temporais para rememorar a trajetória, que foi narrada em Libras com uso da técnica da vídeo-gravação. Como resultado, constataram-se as possibilidades de direcionamento específico durante a orientação para reduzir as limitações da língua, as formas de se trabalhar com esse componente no ensino superior e a realidade apresentada pela estudante.
Abrindo portas para a inclusão
Authors: Baptista Ricardo , Ferreira Maria Eduarda , Costeira João , Martins Maria Helena
Published: February 2023

Investigações assinalam diversos obstáculos no acesso e permanência bem-sucedida dos estudantes com deficiência e/ou necessidades específicas no ensino superior, salientando o papel que os professores detêm neste processo. O objetivo deste estudo foi analisar as perceções, conhecimentos e necessidades de formação de uma amostra de professores de uma instituição de ensino superior pública sobre educação inclusiva e desenho universal para a aprendizagem. A investigação fundamentou-se numa abordagem mista, qualitativa e quantitativa, com desenho transversal, exploratória e descritiva, integrando a aplicação de questionário aos professores. Os resultados obtidos, por meio de análise de conteúdo e das percentagens, evidenciaram demandas de formação no âmbito das práticas inclusivas e do desenho universal para a aprendizagem, nomeadamente dificuldades relacionadas com o desconhecimento das necessidades educacionais destes estudantes e com as metodologias e estratégias. Conclui-se com a necessidade de formação específica sobre estas temáticas de forma a que possam promover um ambiente inclusivo na comunidade universitária.
Educação Física e Inclusão nos Currículos das Universidades Federais da Região Sudeste
Authors: Silva Gabriela Freire da , Santos Paulo Sergio Avelino dos , Seron Bruna Barboza , Salerno Marina Brasiliano , Pimenta Ricardo de Almeida
Published: February 2023

O artigo teve como objetivo analisar as ementas das disciplinas voltadas à inclusão nos currículos dos cursos de graduação em Licenciatura em Educação Física de Universidades Federais da região sudeste brasileira. Essa é uma pesquisa documental e de natureza descritiva, na qual os dados foram obtidos por meio digital, a partir da identificação das Instituições Federais de Ensino Superior. A análise baseou-se no conteúdo ementário das dezesseis disciplinas obrigatórias encontradas, sendo estas distribuídas em cursos ofertados por doze universidades. A partir dos resultados, estabeleceu-se três categorias referentes aos objetos estudados nas disciplinas: 1) Inclusão; 2) Caracterização da deficiência; 3) Ações pedagógicas. Assim, foi percebida a diferenciação na abordagem da temática no ensino superior quando comparada com dados anteriores de análise do currículo da formação inicial em Licenciatura em Educação Física, fato que pode favorecer a perspectiva inclusiva na atuação profissional dos professores.
Modelos didáticos como instrumento de inclusão em aulas práticas de microbiologia
Authors: Tavares Dérica Gonçalves , Antonio Hugo Pereira , Libardi Helena , Cardoso Patrícia Gomes
Published: February 2023

Neste trabalho, relatamos a experiência de incluir um estudante com deficiência visual nas aulas práticas da disciplina de Microbiologia Geral. Como estratégia, foram elaborados alguns modelos didáticos importantes dentro do conteúdo da disciplina. Para sua elaboração, foram utilizados materiais de fácil aquisição e de baixo custo. O uso dos modelos didáticos nas aulas práticas facilitou o aprendizado do conteúdo das aulas, permitindo a identificação dos detalhes microscópicos pelo estudante com deficiência visual e de todos os outros estudantes que demonstraram entusiasmo e interesse, relatando que os materiais lúdicos adaptados auxiliaram no entendimento de várias estruturas e microrganismos observados na microscopia ótica e nas ilustrações de apostila e livros.
Competência comunicativa docente para o ensino de Contabilidade para estudantes Surdos
Authors: Marcelino José Antonio , Morales-Acosta Gina Viviana
Published: February 2023

Este artigo tem como objetivo caracterizar os componentes da competência comunicativa docente para o ensino de Contabilidade Introdutória a estudantes Surdos no curso de Ciências Contábeis, nas regiões Sul e Sudeste do Brasil. Trata-se de uma pesquisa qualitativa, de caráter exploratório, com paradigma interpretativo apoiado por dados visuais. Os sujeitos deste estudo foram cinco professores (ouvintes) que ministravam a disciplina de Contabilidade Introdutória e sete alunos surdos do curso de Ciências Contábeis nas regiões Sul (03 IES) e Sudeste (02 IES) do Brasil. A análise do material textual demonstrou que a presença do intérprete de Libras é essencial para mediar a comunicação entre o docente e o estudante surdo, fazendo a tradução da Língua Portuguesa para a Libras e vice-versa. O ensino inclusivo é um processo em construção que necessita do envolvimento total da comunidade educativa para sua efetivação.
Podcast como ferramenta pedagógica na formação inicial de licenciandos em Física
Authors: Scartezini Brenda Cristina , Arantes Alessandra Riposati
Published: February 2023

O presente trabalho aborda a formação inicial de professores de Física, estudando as potencialidades pedagógicas do uso de podcasts em uma disciplina introdutória do curso de Física Licenciatura da Universidade Federal de Uberlândia (UFU), a fim de tornar os estudantes participantes ativos no processo de ensino e aprendizagem, no contexto do ensino remoto. A pesquisa foi de cunho qualitativo, sendo realizada coleta de dados por meio de diário de campo a partir das observações das pesquisadoras e do preenchimento de questionários pelos licenciandos. A análise dos dados obtidos foi feita de forma indutiva e mediada pela experiência das autoras em sala de aula, baseada em uma abertura crítica às manifestações dos estudantes e aos significados atribuídos por eles às vivências relevantes para o estudo. Os resultados apontaram que o podcast é uma ferramenta promissora para o ensino de Física, pois desenvolve nos alunos habilidades de leitura, escrita de roteiro, gravação, socialização e discussão.
People Factors Influencing Project Success in Software Development: A Survey of Agile Development Teams in Indonesia
Authors: Fadilah Rifa’ah , Raharjo Teguh , Hardian Bob , Suhanto Agus , Fitri Anjani Rufina
Published: February 2023

Currently, agile is one method often used in software development. However, implementing agile is not easy. Many factors can affect the successful implementation of agile software development (ASD). One of the factors that often arise is individuals/people. Previous research has proven that the people factor is one of the factors that can increase the success of ASD implementation. However, only one study focuses on the people factor that researchers in Portugal have done. Therefore, this study attempts to identify the effect of people's factors on the success of ASD in Indonesia. Respondents in this study are individuals who have or are currently using ASD. Data collection in this study used a questionnaire and validated the data using Partial Least Squares–Structural Equation Modeling (PLS-SEM). The findings of this study indicate that team capability influences the success of ASD implementation, while personal characteristics, societal culture, and customer involvement have no effect. In addition, other findings personal characteristics can affect team capabilities and customer involvement.
Comparison Analysis of Fuzzy Sugeno & Fuzzy Mamdani for Household Lights
Authors: Alfian Firdausy Miftah , Utami Ema , Dwi Hartanto Anggit
Published: February 2023

The rapid growth of knowledge and technology in the IoT field encourages scientists to make discoveries in facilitating daily activities by utilizing artificial intelligence, one of which is the Smart Home. Smart home technology is needed that has better advantages over existing building materials, one of which is home lighting or the use of lights. If all this time, houses still use manual control to turn the lights on and off, it will potentially cause the lights to turn on still even though they are not needed, for that we need a method used in the implementation of automatic light control. From several studies, the Fuzzy method is widely used in this case. This method has several models, but the author uses the Fuzzy Mamdani method and the Sugeno method to apply in this study. The variable at the input is the LDR sensor, while the output is a lamp. From the trial results of the two methods, and accuracy test was sought as a parameter for the better ana method. It can be concluded that the Sugeno method has a better accuracy rate of 88.25%, compared to Mamdani's, which is only 84.5%
Deep Learning Approach For Modelling The Spread of Covid-19
Authors: Ukur Ginting Riah , Zarlis Muhammad , Sihombing Poltak , Efendi Syahril
Published: February 2023

In March 2020, the Covid-19 outbreak in Indonesia, where the symptoms of the corona virus made the Indonesian people worry and experience depression. It has been almost two years that Covid-19 has not known what causes it, let alone a person's body condition is not good which can result in being attacked by the virus. Covid-19 first appeared in the city of Wuhan, part of China, where it spread very quickly and was deadly. Its spread through direct physical contact with humans is transmitted through the mouth, nose and eyes, therefore a model is needed for the spread of the corona virus. The spread of COVID-19 affects the pattern of interaction between susceptible (susceptible) and infected (infectious) individuals, where human social contact is very heterogeneous and in groups. To influence the impact of the spread of COVID-19 using deep learning approach that is modeled on the spread of COVID-19, individuals are exposed, infected, recover and die. The purpose of this research is to produce good predictions with a deep learning approach for modeling the spread of COVID-19. The results of the deep learning approach for the COVID-19 spread model carried out the 400 time iteration with an MSE achievement of 0.021112.
Project Management Methodologies for Engineering KMS based on PMBOK Approach: A Systematic Literature Review
Authors: Priyadi Oki , Indra Sensuse Dana
Published: February 2023

The process of creating, sharing, discovering, and capturing knowledge becomes an intangible asset for an organization. As a valuable asset, Knowledge needs to be managed. There is a tool called Knowledge Management System (KMS). The latest technology and social or structural mechanisms are components to develop KMS. But developing an IT project has a high risk of failure, so it should be managed using a project management approach. A project is a temporary endeavor to make a product or service. It means that a project has a start and an end project phase. Some methodologies which exist do not offer complete stages of development KMS. They do not cover feasibility study activities, lack of clear specification, and lack of closing project phase. The study gap is expected to be loaded up and well explained in this paper through a systematic review of the published literature over the last six years using the Kitchenham method. The results show that most researchers used a predictive approach compared to an iterative, incremental, or adaptive development approach to build KMS. The main result of this study we found 36 processes in the developing KMS. The novelty of this research, we generated a table to map the processes into the model, method, artifact and presented it by group process based on the Project Management Body of Knowledge (PMBOK). The table can help the organization develop the KMS project to improve its effectiveness and competitiveness.
A Review on Wind Power Forecasting Models for improved Renewable Energy Integration
Authors: Prasad S Rajendra , Naik M Gopichand
Published: February 2023

This paper gives an overview of the research that has been done on wind power forecasting models, which may be used to aid in the optimum integration of Renewable Energy (RE) into electric power networks. Aside from the economic advantages, the variable nature of wind energy production has a variety of negative consequences for the electric grid system, including stability, reliability, and the capacity to plan for future operations, among other things. As a result, precise forecasting of wind power output is critical for grid stability and security, as well as for the promotion of large-scale wind power. To ensure the accuracy of wind energy forecasts, a variety of conventional, artificial intelligence, and hybrid methodologies have been developed. The simplicity and robustness of time-series-based methods have made them popular for forecasting applications. Artificial Neural Networks (ANNs) and Fuzzy Logic have recently been supported by several researchers for forecasting because of their flexibility. This review covers the performance of many wind power forecasting models that are classified according to their categories. It is also offered a critical examination of contemporary studies, which includes statistical model and machine learning models that are based on historical data. Aspects of this study that are taken into consideration include the advantages and disadvantages of various forecasting models, including hybrid models, as well as performance matrices used in assessing the forecasting model. In addition, the possible advantages of model optimization are examined in detail as well.
Integration of Motor Vehicle Testing Service System with BLUE Smart Card
Authors: Nyoman Harini Puspita Ni
Published: February 2023

The integration of the Motor Vehicle Testing Service System in the regions with the application of the Electronic Test Pass (Bukti Lulus Uji elektronik /BLUe) from the Ministry of Transportation is carried out to improve the quality of motor vehicle testing services. The purpose of this application is to support real-time reporting of motor vehicle testing carried out by the Regions to the Center. This application is made partial, it only accepts test result data without an operational system for the testing process, because of that, motor vehicle testing application that is integrated with the application must be provided. This study aims to build a vehicle testing system that can manage test results automatically and is integrated with BLue. The results of this study are based on the implementation process for three months, the real-time integrated testing service system runs well, which is 94,4 %. the factors that affect the value of 5,6% are influenced by the existing infrastructure and manual payment processes. The calculation of the success of this implementation is determined based on the service target which previously reached 60 minutes per vehicle to 30 minutes, the efficiency of using paper is 66,6%.