bluuebunny/crossref_metadata_2025 huggingface dataset:
Intriguing Thiazolidinediones as PPAR γ Agonists: A Review
Authors: Madhuri P. Laxmi , Rajitha G.
Published: August 2023

Diabetes mellitus is a chronic metabolic disorder marked by persistently elevated blood sugar levels. left untreatedover a long duration can cause multiple body disorders and may cause a person's early death. Though a traditional disorder, typeII diabetes prevalence is increasing daily, especially in the adolescent population worldwide. Peroxisome proliferator-activatedreceptor (PPAR) is a group of receptors consisting of three isoforms (PPAR α, PPAR β/δ, and PPAR γ. PPAR γ is involved inglucose metabolism by facilitating insulin's actions. Thiazolidinedione is a heterocyclic moiety standing pre-eminent in treatingdiabetes mellitus as a PPAR Gamma activator. Thiazolidinedione is a five-membered heterocyclic organic compound, athiazolidine derivative consisting of two carbonyl groups at positions 2 and 4 of the thiazolidine ring. Thiazolidinediones possessan idiosyncratic scaffold featuring a hydrogen bond acceptor region and hydrogen bond donating region at the third and fifthpositions. Thiazolidinedione is an indispensable pharmacophore with many pharmacological activities like antiproliferative,antiviral, antibacterial, tyrosine kinase inhibitory, aldose reductase inhibitory, alpha-glucosidase inhibitory, anti-inflammatory,antioxidant, antitubercular, antihyperlipidemic, etc. Many drugs have been introduced but later have been reticent because ofserious side effects like liver toxicity, CVS toxicity, etc. Pioglitazone and Rosiglitazone have been marketed medications fortreating type II diabetes. This review article deliberates all the cardinal points of thiazolidinediones as PPAR agonists in treatingdiabetes mellitus, which were precluded in some articles. We aim to have an all-embracing review of thiazolidinediones as PPARgamma agonists. The review's objective is to inspire researchers to develop a more superior, secure, and efficient anti-diabeticmedication by thoroughly understanding the molecular mechanisms of thiazolidinediones at the PPAR gamma receptors, theirrisks, and the effect of the various substitutions on the thiazolidinedione.
Pura fibra: tejer pensamiento, pensar tejiendo
Authors: Reyes Suárez Margarita
Published: August 2023

El tejido es una creación que responde a necesidades del cuerpo y el espíritu. Para muchas culturas indígenas es palabra, canto y mito; es la piel de los animales más respetados y temidos, o el color y el vuelo de las aves. También es depositario de sentimientos, conocimientos y oficio; es, a la vez, creación e imitación de la naturaleza. Observar, pensar, experimentar, tejer, nombrar, conocer, transformar son acciones fundamentales en los procesos llevados a cabo por los grupos humanos para el uso de los recursos naturales. En Colombia existen cerca de 130 especies vegetales entre árboles, plantas, palmas, bejucos y raíces utilizados por diferentes culturas para la obtención de fibras y la creación de objetos para diferentes usos. Estas especies se encuentran distribuidas a lo largo y ancho del territorio colombiano, desde el nivel del mar hasta los 3.200 metros de altura. Cientos de años de conocimientos y prácticas acumuladas han permitido el desarrollo de técnicas de recolección, preparación de las fibras, manipulación y elaboración de objetos de uso cotidiano y ritual. Las piezas que se presentan en esta exposición son el resultado de prácticas culturales con las que se ha buscado dar solución a necesidades cotidianas y espirituales, relacionadas con la recolección y preparación de alimentos, la crianza, la cura de enfermedades, el resguardo del sol, la lluvia y el viento, la protección del cuerpo y el espíritu, entre muchas otras funciones.
UM ESTUDO SOBRE A PERCEPÇÃO DOS ALUNOS DO ENSINO MÉDIO SOBRE A EDUCAÇÃO PARA O TRÂNSITO
Authors: Goi Everaldo Antônio , Steigleder Clara Natália
Published: August 2023

O tema Trânsito pode ser desenvolvido em diferentes níveis de ensino. A pergunta a ser respondida nesta pesquisa é: Como o estudante do Ensino Médio percebe o desenvolvimento deste tema em sua escola? O objetivo é compreender como o estudante do Ensino Médio percebe o trânsito e suas normas, como esse conhecimento é construído a partir da escola e qual a importância deste tema na sua percepção. A pesquisa foi desenvolvida em duas escolas públicas no município de Caçapava do Sul, RS. A metodologia adotada tem abordagem quanti-qualitativa. Constituiu-se em um estudo exploratório, pois visou produzir dados para subsidiar o desenvolvimento da temática trânsito no meio escolar. Para a produção de dados foi aplicado um questionário eletrônico em turmas do 3º Ano do Ensino Médio. Como resultado, aponta-se que os pesquisados demonstram não ter estudado a temática Trânsito, mas consideram importante ser estudada no contexto escolar, inclusive no Ensino Médio para a melhoria do comportamento do trânsito em geral e para a redução de acidentes. Assim, constata-se que esta deve ser tratada no currículo escolar em uma perspectiva interdisciplinar.
A SAÚDE DOS PROFESSORES NO CONTEXTO DA PANDEMIA DA COVID-19: UMA REVISÃO INTEGRATIVA DA LITERATURA.
Authors: Pereira Erika Cristina de Carvalho Silva , Ramos Maély Ferreira Holanda
Published: August 2023

Este estudo teve o objetivo de caracterizar as pesquisas sobre saúde docente no contexto da pandemia. Realizou-se uma Revisão Integrativa da Literatura, de abordagem quanti-qualitativa, nas bases de dados Capes, Scielo e Lilacs, levantando artigos sobre a temática dos anos de 2020 e 2021. Utilizou-se a análise descritiva para os dados quantitativos e aplicou-se a técnica de Análise de Conteúdo para os dados qualitativos. Os resultados mostraram que o tema da saúde docente no contexto da pandemia é de interesse global uma vez que já existem publicações desenvolvidas em maior parte dos continentes. As buscas resultaram na seleção de dez artigos de acordo com critérios de elegibilidade pré-estabelecidos. Contatou-se que todas as pesquisas foram empíricas, em sua maioria de natureza quantitativa e aplicada com professores da Educação Básica. Além disso, a análise de conteúdo denotou a presença de seis categorias mais investigadas nos artigos: Problemas de Saúde mental (f = 22), Condições de Trabalho (f = 14) e Problemas físicos de saúde (f = 8), Prevenção e Intervenção para saúde docente (f  = 7), Relações Sociais alteradas (f  = 6), Aspectos cognitivos (f  = 5). Conclui-se que as mudanças ocorridas em razão da pandemia da COVID-19, trouxeram repercussões negativas para a saúde e trabalho dos professores ao redor mundo, uma vez que os estudos apontaram prevalência de problemas relacionados à saúde física e mental, condições de trabalho adversas, mudanças nas relações sociais, alteração nos aspectos cognitivos e necessidade de prevenção e intervenção para a saúde destes profissionais.
NOVO CONSTITUCIONALISMO LATINO-AMERICANO E HISTÓRICO DE CENTRALIZAÇÃO POLÍTICA DA AMÉRICA LATINA:
Authors: Soares João Gabriel , Bastos Elísio
Published: August 2023

Este artigo analisa criticamente a construção do Novo Constitucionalismo Latino-Americano a partir da perspectiva de uma sala de máquinas. Para tanto, abordamos inicialmente a formação da sua evolução histórica e construção de características essenciais para identificação do fenômeno (os elementos materiais e formais comuns e rasgos identificadores) e, posteriormente, discutiremos seus três estágios de manifestação: constitucionalismo multicultural (1982 a 1988); constitucionalismo pluricultural (1988 a 2005); e o constitucionalismo plurinacional (2006 a 2009). Como a proposta do trabalho é discutir seus pontos de inflexão, arguimos que o fenômeno navega em cabotagem em sua transição paradigmática, ou seja, precisa refletir sobre a histórica sala de máquinas latino-americana para alcançar a efetiva solidariedade. Ao fim, conclui-se há um traço marcante do constitucionalismo nesta região e que reforça uma dimensão de colonialidade do poder, sendo necessário reconhecer a existência de Executivos historicamente hipertrofiados e Constituições comprometidas a quando da análise da posição dogmática que tais Constituições visam efetivar. Logo, trata-se de uma pesquisa exploratória do fenômeno, com metodologia teórico-descritiva e viés qualitativo, com proposta crítica reflexiva sobre a efetivação das discussões relativas às recentes promulgações de Constituições na América Latina, sendo tal compreensão crítica pouco explorada pelas pesquisas que tratam sobre este fenômeno.
Penggunaan Model Problem Based Learning (PBL) untuk Meningkatkan Hasil Belajar Siswa
Authors: Mainake Patresya Nova , Laamena Christina M. , Gaspersz Magy
Published: August 2023

Kemampuan siswa dalam memahami materi Sistem Persamaan Linier Tiga Variabel (SPLTV) masih menjadi masalah penting yang harus diselesaikan.  Guru sebagai pendidik perlu menggunakan berbagai model pembelajaran untuk meningkatkan hasil belajar siswa.  Penelitian ini bertujuan untuk mengetahui adanya peningkatan hasil belajar siswa kelas X SMAN 6 Ambon yang diajarkan menggunakan model Problem Based Learning (PBL) pada materi SPLTV. Jenis penelitian yang digunakan adalah penelitian tindakan kelas (PTK) yang terdiri dari 2 siklus dan setiap siklus terdiri dari 2 pertemuan.  Sumber data adalah guru dan siswa kelas X-IPA1 SMAN 6 Ambon tahun ajaran 2019/2020 sedangkan yang menjadi subjek penelitian adalah 25 siswa.  Instrumen penelitian yang digunakan adalah tes hasil belajar SPLTV yang telah divalidasi oleh ahli.  Untuk mengumpulkan data, peneliti menggunakan teknik tes dan observasi. Hasil penelitian menunjukkan bahwa terjadi peningkatan hasil belajar siswa.  Pada siklus I, hanya 11 siswa yang tuntas (44%) tetapi pada siklus II jumlah siswa yang tuntas meningkat menjadi 19 siswa (76%).  Berdasarkan ketuntasan pada siklus I dan siklus II, maka terjadi peningkatan dari siklus I ke siklus II sebesar 32%.
Peningkatan Kemampuan Siswa dalam Menyelesaikan Masalah Matematika dengan Pembelajaran Daring Asinkronus dan Sinkronus
Authors: Mairing Jackson Pasini , Rezeki Maulida , Aritonang Henry , Lada Elyasib Yunas , Langkis Langkis
Published: August 2023

Pembelajaran daring selama pandemi Covid-19 mengalami berbagai kendala terutama pada kuota, sinyal internet dan hasil belajar yang kurang memuaskan. Penelitian ini bertujuan untuk meningkatkan kemampuan siswa-siswa SMP kelas 7 dalam menyelesaikan masalah matematika melalui pendekatan asinkronus dan sinkronus menggunakan video pembelajaran, lembar kerja siswa dan masalah matematika. Penelitian ini tergolong penelitian tindakan kelas. Subjek penelitiannya adalah 14 siswa kelas 7 dari salah satu SMP negeri di pinggiran kota Palangka Raya, Kalimantan Tengah tahun ajaran 2021/2022. Penelitian dilaksanakan dalam dua siklus dimana tahap-tahap di setiap siklusnya adalah perencanaan, pelaksanaan, pengamatan dan refleksi. Instrumen penelitiannya adalah rencana pelaksanaan pembelajaran, masalah matematika, lembar kerja siswa, video, kuis prapembelajaran dan tes akhir siklus. Hasil penelitian siklus I menunjukkan bahwa rata-rata skor siswa sebesar sebesar 7,1 (skala 0-16) dimana 5 dari 14 siswa (35,7%) memperoleh skor setidaknya 2 (skala 0-4) di setiap masalah. Pada siklus II, rata-rata skor siswa sebesar 10,4, dan semua siswa memperoleh skor setidaknya 2 di setiap masalah. Jadi, pembelajaran daring dalam penelitian ini mampu meningkatkan kemampuan siswa dalam menyelesaikan masalah matematika.
Student Errors in Solving Number Patterns, Sequences, and Series HOTS Types Based on Newman's Theory in Terms of Gender
Authors: Siagian Qania Agustika , Herman Tatang , Darhim Darhim , Khairunnisa Khairunnisa
Published: August 2023

This study aims to analyze the errors of students with HOTS abilities at high, medium and low levels and identify student errors in solving HOTS (Higher Order Thinking Skill) type questions in terms of gender. This type of research is qualitative with a case study approach. The research subjects were selected 3 male students and 3 female students, each of which the HOTS ability level was high, medium and low consisting of 2 students. Data collection techniques used HOTS-type tests and interviews. The analytical framework was developed based on Newman's theory of error categories. The data obtained were tested for validity through credibility, transferability, dependability, and confirmability tests. The results showed several differences in the types and percentages of errors made by male and female subjects in solving HOTS-type questions. The biggest mistakes made by both genders in the material of number patterns, sequences, and series are misunderstandings of 33.33%, followed by errors in determining the final answer of 23.02%, transformation errors of 22.22%, errors in the completion process of 20.63%, and finally, reading errors of 0.79%. It can be seen that the female gender makes more mistakes by 57.14% compared to the male gender by 41.86%.
Pengembangan LKS Berbasis Etnomatematika untuk Memfasilitasi Kemampuan Representasi Matematis
Authors: Astuti Novita , Jana Padrul , Marsiyam Marsiyam
Published: August 2023

Kemampuan representasi matematis siswa Sekolah Menengah Pertama (SMP) masih belum maksimal. Penelitian ini bertujuan untuk mengembangkan lembar kegiatan siswa (LKS) dengan kriteria valid, praktis dan efektif berbasis etnomatematika yang secara spesifik dapat memfasilitasi kemampuan representasi matematis siswa. LKS tersebut dikembangkan dalam rangka memfasilitasi kemampuan representasi matematis siswa melalui gambar dan simbol. Penelitian ini menggunakan metode penelitian dan pengembangan (R&D) dengan menerapkan model ADDIE yaitu: analysis (analisis), design (desain), development (pengembangan), implementation (implementasi), dan evaluation (evaluasi). LKS diuji cobakan kepada 32 siswa kelas 7B SMP N 1 Mlati tahun ajaran 2020/2021. Instrumen yang digunakan yaitu lembar pedoman wawancara, angket penilaian ahli materi dan ahli media, angket respon siswa dan guru, lembar observasi keterlaksanaan pembelajaran, dan soal tes kemampuan representasi matematis. Berdasarkan hasil penelitian diperoleh: (1) LKS dinyatakan “valid” dengan persentase skor rata-rata ahli 81,03% dengan kriteria sangat baik. (2) LKS dinyatakan “praktis” dengan skor rata-rata angket respon pendidik dan siswa terhadap LKS yaitu 4,2 dengan kriteria baik, serta hasil observasi keterlaksanaan pembelajaran diperoleh persentase skor rata-rata 92,33% dengan kriteria sangat baik. (3) LKS dinyatakan “efektif” dengan persentase skor rata-rata hasil tes kemampuan representasi matematis yaitu 76,92% dengan kriteria baik. LKS yang disusun memenuhi kriteria valid, praktis, dam efektif sehingga dapat digunakan dalam pembelajaran.
Difficulties of Pre-Service Mathematics Teacher Students in Determining the BASE and Numerus of Logarithmic Materials
Authors: Kurniawan Surya , Suhendra Suhendra
Published: August 2023

Logarithm has an important role in learning mathematics since various fields such as science, computer, finance, industry, and others are applied this material as one of the study subjects. In calculus, logarithm has an important role, especially natural logarithm. This study aims to determine pre-service mathematics teachers' difficulties in solving logarithm bases and numerus material. The subjects are students in the first semester in one university at Banda Aceh city who take elementary algebra course. The research was conducted with a descriptive approach to explain the difficulties that students faced, and it applied several steps such as providing logarithm test to students, determining the difficulties, and verifying it by interviewing students who had difficulties based on their answers. This study revealed that there were various difficulties that students faced such as; (1) lack of understanding of bases and numerus definitions of logarithms, (2) not being able to distinguish between expressions and logarithmic equations, (3) remembering too many formulas so that they do not understand the context of the problem, (4) couldn’t determine the position of irrational numbers on the number line.
Konsepsi Guru Matematika SMA tentang Berpikir Kreatif
Authors: Wicaksono Arief Budi , Khabibah Siti , Masriyah Masriyah
Published: August 2023

Penelitian ini bertujuan untuk mendeskripsikan konsepsi guru matematika SMA tentang berpikir kreatif. Pendekatan penelitian yang digunakan adalah deskriptif kualitatif. Subjek dalam penelitian ini merupakan seorang guru matematika SMA di Yogyakarta. Penelitian ini menggunakan hasil kuesioner terbuka sebagai data utama dan wawancara sebagai data penunjang. Hasil penelitian menunjukkan bahwa konsepsi guru matematika tentang berpikir kreatif terbatas pada cara berpikir/ menyelesaikan suatu masalah dengan menggunakan langkah-langkah atau ide-ide baru sehingga menemukan/menghasilkan sesuatu yang baru/berbeda dari biasanya. Guru matematika kreatif digambarkan mampu memunculkan ide-ide baru, mampu membuat inovasi baru dalam pembelajaran. Guru berperan aktif dalam membimbing siswa agar mampu berpikir kreatif dengan memberikan pertanyaan-pertanyaan atau tugas pemicu matematika yang berbentuk uraian (soal terbuka) sehingga siswa dapat mengeksplor kemampuannya untuk memicu berpikir kreatifnya. Guru menilai kemampuan berpikir kreatif dengan cara memberikan soal terbuka/ tugas pemicu kemudian dianalisis langkah-langkah pengerjaannya/ hasil pekerjaannya dalam menemukan langkah-langkah/ ide-ide baru dalam proses pengerjaan.
Pendampingan Pemanfaatan Virtual Lab Aplikasi Rumah Belajar untuk Guru dan Siswa SMAN 11 Kota Jambi
Authors: Khaira Ulfa , Aryani Reni , Arsa Daniel , Lestari Dewi , Raaiqa Bintana Rizqa
Published: August 2023

Kementerian Pendidikan dan Kebudayaan telah meluncurkan aplikasi "rumah belajar"tahun 2011, dan terus mengembangkan pembelajaran digital. Aplikasi rumah belajar ini dapat dimanfaatkan secara gratis oleh guru dan murid pada semua jenjang pendidikan. Salah satu fitur yang ada di aplikasi rumah belajar adalah laboratorium maya. Namun, aplikasi ini belum dimanfaatkan secara maksimal. Berdasarkan hasil survei tim Pengabdian kepada masyarakat, selama masa pandemi ini kegiatan pembelajaran dilakukan menggunakan platform Whatsapp grup yang dinilai masih kurang efektif. Selain itu, materi pembelajaran yang memerlukan praktikum tidak dapat dilakukan. Kegiatan pengabdian ini bertujuan untuk pendampingan pemanfaatan laboratorium vitual aplikasi rumah belajar. Kegiatan ini diikuti oleh 3 orang guru IPA dan 35 orang siswa SMAN 11 Kota Jambi. Metode kegiatan yang dilakukan berupa workshop pemaparan materi dan pendampingan penggunaan virtual lab kepada guru dan siswa. Kegiatan dilaksanakan pada tanggal 04 Oktober 2021 bertempat di Laboratorium Komputer SMA N 11 Kota Jambi. Luaran kegiatan ini guru dapat memanfaatkan aplikasi Rumah Belajar dan memaksimalkan penggunaan fitur virtual lab demi meningkatkan efektivitas kegiatan belajar mengajar, sehingga sekolah mampu meningkatkan keberhasilan tujuan pembelajaran yang ingin dicapai. Guru dan siswa dapat mempraktikkan secara langsung fitur-fitur yang ada pada virtual lab rumah belajar kemdikbud dalam mendukung praktikum sains. Pelatihan ini memberikan banyak manfaat kepada guru dan siswa dalam melakukan eksperimen sains seperti pada mata pelajaran Fisika untuk memperkuat konsep teori dari pembelajaran meskipun dalam  kondisi pembelajaran tatap maya.
El uso del Internet y su relación con el crecimiento económico: Análisis para Nicaragua
Authors: Brenes - González Humberto Antonio
Published: August 2023

En los últimos años el Internet ha jugado un rol importante en la dinámica de la economía de los países, por tal motivo, el presente trabajo denominado “El uso del Internet y su relación con el crecimiento económico: Análisis para Nicaragua” tuvo como objetivo establecer la relación que existe entre el uso del Internet y el crecimiento económico para Nicaragua.

El modelo establecido para determinar la relación entre las variables fue bajo un modelo cuadrático, que tuvo como variable dependiente al crecimiento económico, medido por medio del Producto Interno Bruto (PIB), a precios constantes en dólares de 2018 y como variable independiente, al porcentaje de la población que usa Internet.

Los resultados obtenidos bajo el modelo cuadrático planteado fueron estadísticamente significativos, lo cual valida y evidencia la existencia de una fuerte relación entre las variables en estudio, siendo su coeficiente de correlación de un 98.21% y el de determinación de 96.46%.
POTENSI TANAMAN HERBAL BUNGA TELANG (CLITORIA TERNATEA) SEBAGAI ALTERNATIF ANTIHIPERTENSI
Authors: Rizkawati Muflihah , Fairuz Ratna Amalia , Absari Nurmala Widya
Published: August 2023

ABSTRAK

 

Hipertensi merupakan penyebab utama penyakit kardiovaskular dengan angka kematian tertinggi di dunia. Berbagai upaya dapat dilakukan untuk menurunkan peningkatan tekanan darah dengan mengkonsumsi obat antihipertensi, melakukan olahraga dan aktivitas fisik, mengelola stres serta melakukan pembatasan terhadap asupan makanan tinggi garam dan lemak. Permasalahan utama dari sulitnya melakukan kontrol terhadap tingginya tekanan darah adalah lemahnya kepatuhan terhadap konsumsi obat antihipertensi dan sulitnya mengatur pola makan rendah garam dan kolesterol. Selain itu, penggunaan obat jangka panjang dapat memunculkan kecemasan terhadap efek samping. Alternatif pemanfaatan tanaman herbal Bunga Telang (Clitoria ternatea) dapat menjadi pilihan yang lebih baik dalam penanganan hipertensi. Metode yang digunakan dalam penelitian ini adalah literature review dengan melakukan penelusuran artikel dari Google Scholar, Sciencedirect, dan Pubmed yang terbit pada tahun 2012-2022. Berdasarkan hasil telaah jurnal didapatkan 4 artikel sesuai yang menunjukkan adanya efek positif dari bunga telang dalam menurunkan kadar tekanan darah pada studi yang dilakukan.
EPIDEMIOLOGICAL MODEL OF STUNTING DETERMINANTS IN INDONESIA
Authors: Arifuddin Adhar , Prihatni Yuli , Setiawan Ari , Wahyuni Rosa Dwi , Nur A Fahira , Dyastuti Nur Eka , Arifuddin Hidayanti
Published: August 2023

Stunting dapat menghambat pertumbuhan fisik, meningkatkan kerentanan anak terhadap penyakit, hambatan perkembangan kognitif yang menurunkan kecerdasan dan produktivitas anak di masa depan. Penelitian ini bertujuan menggali fenomena determinan stunting pada anak dengan pendekatan epidemiologi. Jenis penelitian kualitatif dengan pendekatan fenomenologi. Partisipan dalam penelitian ini adalah para ibu  yang memiliki anak menderita stunting sebanyak 8 informan di Sulawesi Tengah. Partisipan berusia antara 25 sampai dengan 35 tahun yang berdomisili di daerah perkotaan dan pedesaan. Pengumpulan data menggunakan angket yang dilengkapi wawancara. Penggunaan angket untuk mengeksplorasi faktor risiko dan mengidentifikasi berbagai determinan stunting dengan pendekatan trias epidemiologi.  Hasil penelitian ini menunjukkan bahwa determinan stunting dengan pendekatan trias epidemiologi diantaranya faktor host terdiri dari penyakit infeksi yang diderita, kurang asupan gizi/ status gizi, ketahanan pangan yang rendah, pola asuh/pola makan yang buruk, kualitas dan kuantitas makanan yang rendah, ASI eksklusif, serta gangguan mental dan hipertensi pada ibu. Faktor agent terdiri dari bakteri, parasit dan virus yang mengakibatkan diare, ISPA dan campak pada anak. Faktor environment terdiri dari sanitasi, akses air bersih, bahan bakar memasak, perilaku merokok, dan paparan asap rokok. Pengembangan riset literature review diperlukan dalam menentukan faktor lain sebagai determinan stunting pada anak untuk mengembangkan riset epidemiologi dalam mengendalikan faktor risiko stunting.
Beneficial ownership transparency strategy in law enforcement of the money laundering act involving corporations
Authors: Agustino Leo , Fitriani Indah , Reyta Fitriani , Fajar Ganjar Nurul
Published: August 2023

Corporations play an important role in economic growth and national development. The corporation has the potential to become a means to commit criminal acts of money laundering with the aim of benefiting (beneficial owner). The distribution of beneficial owner information is an effort to realize corporate sustainability. Consistency of beneficial ownership transparency is needed to ensure law enforcement of money laundering crimes involving corporations. The purpose of this study is to find the role of beneficial owners in the misuse of corporations as a mediator for money laundering crimes in Indonesia. This research method uses a normative juridical approach that focuses on data collection techniques, descriptive, and analytical, with literature studies and field studies being the research stage, then the data is analyzed qualitatively. The results of the analysis show that transparency of beneficial owner information is part of the framework of the principles of prevention and eradication of money laundering. Transparency of beneficial owner information can ensure the implementation of practices and concept development that is used as a means of orientation in the prevention and eradication of money laundering crimes involving corporations.
Jellyfish-Inspired Smart Tetraphenylethene Lipids with Unique AIE Fluorescence, Thermal Response, and Cell Membrane Interaction
Authors: Zheng Yujie , Li Yu , Ke Changsheng , Duan Mojie , Ye Chaohui , Zhou Xin , Yang Minghui , Jiang Zhong-Xing , Chen Shizhen
Published: August 2023

Smart lipids with fluorescence emission, thermal response, and
polyethylene glycolation (PEGylation) functions can be highly valuable
for formulation, image-traceable delivery, and targeted release of
payloads. Herein, a series of jellyfish-shaped amphiphiles with a
tetraphenylethene (TPE) core and four symmetrical amphiphilic side
chains were conveniently synthesized and systematically investigated as
smart lipids. Compared with regular amphiphilic TPEs and phospholipids,
the unprecedented jellyfish-shaped molecular geometry was found to
enable a series of valuable capabilities, including sensitive and
responsive aggregation-induced emission of fluorescence (AIE FL) with
high quantum yields, efficient encapsulation of drugs into stable
nanoparticles, PEGylation of nanoparticles with thermally responsive
drug release, and real-time FL monitoring of drug uptake. Furthermore,
the jellyfish-shaped geometry facilitated the concentration-dependent
aggregation of unimolecular micelles into “side-by-side” assembled
nanoparticles with a unique mode of AIE. In addition, the size and the
arrangement of the amphiphilic side chains were found to dominate the
aggregate stability, cell uptake, and thus the cytotoxicity of the
amphiphiles. The study has unprecedentedly developed versatile smart TPE
lipids with precise structures, unique physicochemical and biological
properties, and great potential in biomedicine, which peculiar
structure-property relationship may shed new light on the design and
application of AIE fluorophores and functional lipids in biomedicine and
materials science.
How to manage the aspergillus skull base osteomyelitis when it is only a probable diagnosis?
Authors: Cao Xihong , Wang Yating , Zhang Qingyu , Chen Lijuan , Zhu Zhengwen , Jie Huang
Published: August 2023

Purpose:Aspergillus basicranial infection is a rare disease, often
associated with delayed or unproven diagnosis, the management of which
is unclear. Methods:We report a probable case of otogenic skull base
aspergillus osteomyelitis,review invasive basicranial
osteomyelitis,manage and follow up the patient by galactomannan(GM) test
and magnetic resonance imaging(MRI) during the treatment of
voriconazole. Results:
Xiangpi shengji onitment promotes infected wound healing in rats via the PI3K/AKT/HIF-1α signaling pathway
Authors: Ding Hongmei , Chen Liming , Huang Jin , Zhai Mengying , Zhou Yongmei , Dong Benchao , Bai Xue , Chen Desheng , Wang Yi
Published: August 2023

Xiangpi Shengji Onitment (XPSJO) is a hospital preparation commonly used
in clinic to treat large areas of bedsores and chronic non-healing
wounds. However, a complete understanding of the molecular mechanisms is
still lacking. This study used rats to explore the healing mechanisms of
XPSJO in promoting infected wound healing. Forty-five male Sprague
Dawley (SD) rats were randomly divided into model control group, XPSJO
group and basic fibroblast growth factor (bFGF) group. The wound
contraction was quantified on days 3, 7 and 14 after medication.
Hematoxylin and eosin stains were performed for histopathological
evaluation. The levels of tumour necrosis factor-α (TNF-α), interleukin
(IL)-1β, matrix metalloproteinase 2 (MMP2), MMP9 and vascular
endothelial growth factor (VEGF) were detected by enzyme-linked
immunosorbent assay (ELISA). Protein expression of PI3K, p-PI3K, AKT,
p-AKT and HIF-1α were detected by western blot analysis. XPSJO
significantly enhanced the wound healing rate, and more blood vessels
and fibroblasts were observed in the regenerated tissues in XPSJO
treatment group. ELISA results showed that XPSJO significantly decreased
the levels of TNF-α and IL-1β and increased the levels of VEGF in wound
tissue. XPSJO increased the levels of MMP2 and MMP9 in early stage of
wound healing. In addition, activated PI3K/AKT/HIF-1α signaling pathway
was detected in the XPSJO treatment group.
Patients’ Characteristics and Environmental Factors Affecting Skin Cancer Detection: A Multicentre Prospective Study
Authors: Iglesias-Puzas Álvaro , Conde-Taboada Alberto , Aranegui-Arteaga Beatriz , Campos-Muñoz Lucía , López-Bran Eduardo
Published: August 2023

Abstract is missing (Short communication)
Examination of Foreign Language Teachers Commitment Levels to Curriculum During the Covid-19 Pandemic Period
Authors: Eker Cevat , Şenel-Öksüz Elif
Published: August 2023

In this study, the aim was to examine foreign language teachers’ commitment levels to the curriculum working in formal primary and secondary education institutions during Covid-19 pandemic period. With this general purpose, foreign language teachers’ level of commitment to the curriculum was compared in terms of different variables (gender, type of school they graduated from, teaching level, year of experience). In this respect, this study is descriptive research in the scanning model. The study was carried out with the participation of 92 foreign language teachers working in primary and secondary education in a city center located in the Western Black Sea Region of Turkey in the 2020-2021 academic year. In the study, the ‘personal information form’ developed by the researchers and the ‘Curriculum Commitment Scale’ developed by Yaşaroğlu and Manav (2015), was employed as data collection tools. Frequency, percentage, arithmetic deviation in data analysis; t Test for Independent Groups were used to compare the means of two groups, and One-way Analysis of variance was used to compare the means of more than two groups. As a result it was concluded that the commitment level of foreign language teachers to the curriculum is high and there is no significant difference in the level of commitment to curriculum according to their demographic characteristics.
Trials for – Trials Against: Analyzing Efficacy of Glucosamine and Chondroitine for Osteoarthritis
Authors: AP Rozin
Published: August 2023

New approach to find effective remedies against osteoarthritis (OA) is actual because total treatment failure. Simultaneous existence of data explaining efficacy of glucosamine and chondroitine against osteoarthritis along with articles certifying failure of such effect raise permanent discussion. This controversy is extended with assessment of proposed infectious theory of osteoarthritis. There are several lines of suspicion for involvement of infectious factors in development of osteoarthritis and for antibacterial properties of glucosamine and chondroitine. From this view possible explanations of the trials’ discrepans in GS-CS efficacy-failure against osteoarthritis follow. Along with ethiology different clinical aspects and mechanisms should not be missed in patients with OA, which may be due to infectious factors. Large meta-analysis trials may miss important information considering large non-specific cogorts of patients. There are several teaching points for further investigation in this letter. Large meta-analysis studies cannot take into account all specific groups of patients and general data may miss an important information. In order to realize a nature of osteoarthritis specific homogenous groups for each parameter should be collected and examined. Occasional data may cary light for deep mechanisms of the disease and its therapy.
Role of Low Level Laser Therapy in Macrodactyly
Authors: RK Chittoria
Published: August 2023

The effectiveness of low level laser therapy (LLLT) for macrodactyly to reduce the bulk of the tissue has not been discussed much in the literature. Although low level laser therapy & its effectiveness and the process by which it reduces body fat from fat cell is inadequate this study tries to review the literature & its application. In our study low level laser therapy was used in a subject with left big toe macrodactyly to evaluate the efficacy.
Museu estadual de carvão
Authors: Weber Dorcas , Oliveira Juliana
Published: August 2023

Pelas ações educativas busca-se formar o indivíduo para a vida e, para isso, é essencial que durante sua formação tenha contato e experiências com o mundo e sua cultura. Estas permitem que ele se aproprie de culturas diversas e, também, reproduza a sua cultura e seus saberes, compreendendo melhor a si e aos outros. Este trabalho versa sobre a cultura, apropriação de patrimônio e formação integral e teve por objetivo compreender como os espaços culturais podem ser potenciais educativos para os processos de ensino e aprendizagem que ocorrem no contexto escolar. Para tal foi realizada uma pesquisa bibliográfica acerca de teorizações sobre conceito de museus e sobre o Museu Estadual do Carvão. Ainda, foi realizada uma pesquisaação na qual foi elaborado um projeto, desenvolvido junto ao estágio de docência, propondo ações educativas a serem realizadas na escola que integrassem o museu e currículo escolar. O resultado desta pesquisa mostra a potencialidade das atividades em sala de aula que agregam os contextos históricos e culturais do espaço pesquisado e seus desdobramentos nos componentes curriculares.
Introduction of Avocado (Persia americana) Fruits in Eastern Himalaya of India: A Review
Authors: Subba Saidiksha , Gurung Sarad , Mahato S. K. , Thapa Bandan , Chhetri Binoy
Published: August 2023

Avocado (Persia americana) or locally called Phamfal is a subtropical, dicotyledonous, evergreen tree belonging to the family Lauraceae. The avocado tree is originated from a broad geographical area stretching from the eastern and central highlands of Mexico through Guatemala to the Pacific coast of Central America. Avocado is a fruit, produced from tropical trees characterized by a pear shape and blackish green in colour with high nutritional value and creamy texture. Avocado crop can be used in several ways i.e for processed products, exportation and oil extraction, pharmaceutical and cosmetic industries as a raw material thereby generating high value added products.High demand for information on avocado indicates that there is considerable interest in this crop in various parts of India as well as Eastern India. Moreover, avocado can be grown in Darjeeling hilly region and adjoining states of India as the soil and climatic condition is favourable for their growth and development. However, in this region avocado cultivation is very negligible in homestead garden, small and marginal orchard due to lack of scientific knowledge of farmers. So that in this context to identify and conservation of wild and farmers cultivated species of avocado is the major concern for all avocado growers and scientist.
Relationship Analysis of Spiritual Intelligence with Life Satisfaction of College Students
Authors: Gill Suman , Sharma Seema , Kang Tejpreet K.
Published: August 2023

The present study was conducted during December-January, 2022–23 at Ludhiana, Punjab, India to assess the relationship between spiritual intelligence and life satisfaction among college students. The sample consisted of 220 college students aged between 23–24 years. The sample consisted of equal number of male (n=110) and female (n=110) students. Random sampling was done to draw sample from four colleges of district Ludhiana. The objective of the study was to assess the relationship between spiritual intelligence and life satisfaction of college students. Sixfold spiritual intelligence scale by Kaur (2017) and Life satisfaction scale by Singh and Joseph (2015) were used as data collection tools to assess the spiritual intelligence and life satisfaction of college students. Gender wise mean score differences among college students across different dimensions of spiritual intelligence revealed no significant differences among various dimensions. Gender wise mean score differences among college students across different levels of life satisfaction showed a significant difference at low level of life satisfaction. The results revealed that all the dimensions of spiritual intelligence were positively related to life satisfaction of male and female college students. It would be also helpful for parents, counsellors, psychologists and human development professionals to understand the level of spiritual intelligence of college students. The present study will be useful for the youth to understand the importance of spiritual intelligence and its relationship with life satisfaction.
Assessing the Nutritional and Antinutritional Components of Promising Kabuli Chickpea (Cicer arietinum L.) Genotypes
Authors: Kumar Tajender , Timbadiya P. N. , Kandoliya U. K. , Parakhia M. V. , Gajera H. P.
Published: August 2023

The present investigation on “Assessing the Nutritional and antinutritional componants of promising   kabuli chickpea (Cicer arietinum L.) genotypes” was carried out with an objective to analyze different 20 promising genotypes of kabuli chickpea for various nutritional and anti-nutritional components. The highest protein content (25.37%) and phytic acid (12.29 mg g-1) were recorded in kabuli chickpea genotype GJGK-1828. The highest value of total sugar content was observed in ICCV-191310 (4.73%) and maximum ash content was found in ICCV-191302 (3.47%). The minimum phytic acid was recorded in genotype ICCV-191301(10.43 mg g-1) which found distant genotypes in dendrogram prepared using biochemical data. The higher trypsin inhibitor was recorded in kabuli chickpea genotype GJGK-1826 (10.33TIU/mg) and lowest trypsin inhibitor content noticed in genotype ICCV-191302 (14.33TIU/mg) and both were fall in different cluster of dendrogram. Minimum value of total phenol was found in ICCV-181314(87.87 mg 100 g-1) and maximum value was observed in kabuli chickpea genotype GKGK-1826 (93.98 mg 100 g-1). Thus, the wide variability of nutritional and antinutritional parameters was observed among the genotype studied.
Analysis of Work Readiness Based on Soft Skills, Machining Knowledge, and 5S Work Culture
Authors: Maulidina Ainun , Wijanarka Bernardus S.
Published: August 2023

The aims of this study were to analyze 1) the influence of soft skills on the work readiness of students at Mechanical Engineering Vocational High Schools in the city of Palembang; 2) the effect of machining knowledge on the work readiness of students of Mechanical Engineering Vocational High Schools in the city of Palembang; 3) the effect of 5S work culture on the work readiness of students of Mechanical Engineering Vocational High Schools in Palembang city; and 4) the influence of soft skills, machining knowledge, and 5S work culture simultaneously on the work readiness of students of the Mechanical Engineering Vocational High School in the city of Palembang. The research method used is correlational research. The subjects of this research were class XII students of Mechanical Engineering Vocational Schools in Palembang City, recruited using a purposive sampling technique with the provision that students would work after graduating from Vocational High School. Thus, for a population of 360, the total sample was 187 respondents. The technique of collecting data for this research is a questionnaire and multiple-choice tests. Data analysis techniques were performed using correlational statistical analysis and regression analysis. The results of the study were the following: 1) Soft skills have a positive and significant effect on work readiness by 34.56%; 2) Machining knowledge has no effect on job readiness; 3) 5S work culture has a significant and positive effect on work readiness by 15.90%; and 4) Soft skills, machining knowledge, and 5S work culture have a positive and significant effect on work readiness by 53.5%.
Non-English Majors' Problems in Learning English Vocabulary and Strategies Revisited
Authors: Wang Shuoying , Ge Shan , Tang Chang
Published: August 2023

English vocabulary learning is the focal point of English learning and has posed great difficulty to non-English majors. A survey conducted by the authors showed that non-English majors generally have such problems in English vocabulary learning as lack of English language environment, isolated vocabulary memorization, difficulty in retention, and the negative influence of the mother tongue. The corresponding strategies to tackle these problems include situational vocabulary learning, differentiation and induction, regular review and learning by association. Students should choose the learning strategies that best suit them so as to improve the effect of English learning.
Literature Study of Islamic Values Integration in Biology Subject in SMA/MA (Senior High Schools/Islamic Senior High School)
Authors: Zahro' Anisatuz , Muzazzinah Muzazzinah , Ramli Murni , Wulandari Eka
Published: August 2023

Because science, including biology, has a tight relationship with Islamic knowledge, learning biology in schools should not be viewed as a monodisciplinary that stands alone but rather as having an axiological value system tied to other disciplines. This sort of research is literature research that refers to a previously conducted issue and tries to identify the extent to which the integration process of Islamic principles in Biology learning in SMA/MA (Senior High Schools/Islamic Senior High Schools) has been carried out. The data was collected through secondary sources such as credible national and international journal publications published in the Google Scholar database. The findings of this study indicate that the application of the integration of Islamic values in biology learning in SMA/MA can be made through several models, including (1) the Al-Qur'an integration model as a source of inspiration, namely placing the Qur'an at the beginning of learning as an umbrella of knowledge; and (2) the Qur'an integration model as a source of confirmation, namely scientific findings are to clarify what has been stated by the Qur'anABSTRAK: Ilmu sains termasuk Biologi mempunyai hubungan yang erat dengan pengetahuan Islam sehingga pembelajaran Biologi di sekolah semestinya tidak hanya dipandang sebagai monodisiplin ilmu yang berdiri sendiri, tetapi secara aksiologis memiliki sistem nilai yang berkaitan dengan disiplin ilmu lainnya. Jenis penelitian ini merupakan penelitian kepustakaan (literature research) yang mengacu pada suatu topik yang sebelumnya pernah dilakukan yang bertujuan untuk mengetahui sejauh mana proses integrasi nilai-nilai Islam yang telah dilakukan dalam pembelajaran Biologi di SMA/MA. Data yang diperoleh berupa data sekunder yang bersumber pada artikel jurnal nasional maupun internasional yang diterbitkan dalam database Google Scholar. Hasil penelitian ini menunjukkan integrasi nilai-nilai Islam dalam pembelajaran Biologi di SMA/MA, diantaranya adalah (1) model integrasi Al-Qur’an sebagai sumber isnpirasi, yaitu meletakkan Al-Qur’an pada awal pembelajaran sebagai payung pengetahuan; (2) model integrasi Al-Qur’an sebagai sebagai sumber konfirmasi, yaitu temuan dalam sains adalah memperjelas apa yang telah dikermukakan Al-Qur’an.
Seasonal incidence, population dynamics and morphometric traits of exotic coconut whiteflies in southern Tamil Nadu
Authors: Suriya S , Preetha G , Balakrishnan N , Sheela J
Published: August 2023

Survey was conducted at fortnightly intervals to assess the intensity of damage caused by the invasive whiteflies in coconut in the southern districts of Tamil Nadu viz., Thoothukudi, Tirunelveli, Tenkasi and Kanyakumari from December 2020 to August 2021. Among the four districts, Kanyakumari recorded the highest whitefly incidence (56.30%), whereas, Tenkasi showed the lowest infestation (48.83%). Two whitefly species viz., rugose spiralling whitefly, Aleurodicus rugioperculatus Martin and bondars nesting whitefly (BNW), Paraleyrodes bondari Peracchi were observed in all the surveyed districts. The rugose spiralling whitefly nymphs and adult populations were found to be highest in Kanyakumari (49.46 nymphs/leaflet; 36.99 adults/leaflet) and lowest in Tenkasi (32.76 nymphs/leaflet; 26.71 adults/leaflet). Similarly, the population of bondars nesting whitefly nymphs and adults were highest in Kanyakumari (35.31 nymphs/leaflet; 34.84 adults/leaflet), whereas, the lowest nymphal population was observed in Tenkasi (22.79 nymphs/leaflet) and adult population in Thoothukudi (24.19 adults/leaflet). In morphometric analysis, length and breadth of egg (0.24 ± 0.03 mm and 0.13± 0.02 mm), nymphal (0.83 ± 0.08 mm and 0.38 ± 0.04 mm), pupal (1.08 ± 0.09 mm and 0.70 ± 0.09 mm), adult (female: 2.59 ± 0.09mm, 1.71 ± 0.14 mm; male: 2.27 ± 0.21 mm, 1.30 ± 0.05 mm) was recorded for A. rugioperculatus and egg (0.15 ± 0.02 mm and 0.08 ± 0.01 mm), nymphal (0.46 ± 0.02 mm and 0.36 ± 0.02 mm), pupal (0.59 ± 0.16 mm and 0.41 ± 0.09 mm), adult (1.09 ± 0.08 mm and 0.73 ± 0.07 mm) for P. bondari.
Revolución y ciudadanía en el radicalismo argentino (1890-1930)
Authors: Giménez Sebastián R.
Published: August 2023

El presente artículo busca analizar los diferentes sentidos que adoptó el concepto de revolución en la discursividad política de la Unión Cívica Radical en el período comprendido entre 1890 y 1930. Los vínculos entre el radicalismo y la práctica revolucionaria fueron notorios en la etapa formativa del partido. Y, aunque luego de sancionada la Ley Sáenz Peña, la UCR abandonó la estrategia armada para priorizar su conformación partidaria electoral, el componente disruptivo de su identidad no se desactivó, sino que continuó estructurando la gramática discursiva del movimiento. La “revolución”, por consiguiente, no desapareció del horizonte identitario del radicalismo aunque ella se ligó ahora a nuevos significados y sentidos. El artículo se propone entonces identificar y analizar los diferentes usos del concepto de revolución en la UCR en las cuatro décadas comprendidas entre la fundación del partido y el golpe de estado de septiembre de 1930. Esperamos con ello contribuir a la elucidación de las tensiones conceptuales que atravesó la implantación de la institucionalidad liberal-democrática en la Argentina contemporánea.
Pelos que importan
Authors: Liarte Tiloca Agustín , Peirone Franco
Published: August 2023

El presente texto parte de dos investigaciones etnográficas, preocupadas por indagar sobre corporalidades y presentaciones de género a partir del estudio de performances estético-políticas en la ciudad de Córdoba. Una de estas pesquisas analiza la construcción de masculinidades entre sujetos que asistían a fiestas de osos, eventos nocturnos que convocaban a varones que mantenían contactos erótico-sexuales con otros varones, y que posicionaban la masculinidad como un vector de deseo. Por otro lado, una pesquisa centrada en examinar las prácticas depilatorias en un centro de estética, al que acudía un público conformado en su mayoría por mujeres cisgénero. Desde un conjunto de lecturas enfocadas en la construcción histórica, performativa y prostética de los cuerpos, nos preguntamos por el lugar que ocupaban los pelos en la producción de corporalidades generificadas. La presencia o ausencia de estas vellosidades marcaban para distintos grupos de personas la autoadscripción a categorías de masculinidad y feminidad.