bluuebunny/crossref_metadata_2025 huggingface dataset:
Achieving Digital Medicine Learning Outcomes Through an Interdisciplinary Course: A Pilot Study
Authors: Mielitz Annabelle , Friederichs Hendrik , Bittner Anja , Albrecht Urs-Vito
Published: November 2024

Incorporating digital medicine into medical education equips students for the evolving landscape of healthcare. This study aimed to assess a digital medicine course developed at Bielefeld University by evaluating student attainment of learning outcomes outlined by Foadi et al. In the course, the students designed a digital application for various medical conditions, taking into account interdisciplinary factors. The course took place in 2023 with medical students who attended the course due to the focus of their studies. In a pilot study, the progress of ten participants was assessed using a pre-post survey design. Results revealed substantial improvement in students’ achievement of learning outcomes post-course (median = 2, IQR 1-2) compared to pre-course (median = 3, IQR 3-4), suggesting the course’s efficacy in effectively teaching digital medicine.
Organizing an Interdisciplinary Platform for Knowledge Sharing on a Class of Compounds of Natural Origin
Authors: Murgia Ylenia , Iobbi Valeria , Bisio Angela , de Tommasi Nunziatina , Giacomini Mauro
Published: November 2024

Sesterterpenoids, a subset of the terpene family, exhibit notable biological activities. These natural compounds are present in a variety of organisms such as plants, fungi, bacteria, insects and marine life. The therapeutic potential and structural diversity of sesterterpenoids have attracted considerable interest in pharmacological and chemical research. This study illustrates the development of a database to structure and manage data on these compounds. The design process involves the collection of user requirements, creation of a conceptual model with and Entity-Relationship Diagram (ERD), development of a logical model, and implementation in Microsoft SQL Server 2022. Data collection began with an extensive literature review and organization in an Excel spreadsheet. The resulting database improves data acquisition, organization, and accessibility. Future work will include building a website to facilitate data entry, editing, reading and extraction, and automation of data updates via external web services.
Designing a User-Friendly Data Request Management System for a Growing Health Data Network – A Case Study in the AKTIN Registry
Authors: Kombeiz Alexander , Bienzeisler Jonas , Majeed Raphael W. , Röhrig Rainer , Aktin Research Group
Published: November 2024

The AKTIN Emergency Department Registry, a German health data network, faces operational challenges due to rapid growth. Manual data request processes have become inefficient, hindering timely research and straining personnel. To address these challenges, we undertook a user-centered analysis utilizing Design Thinking principles to identify pain points and functional requirements in current data request creation and management processes. Future work will prioritize iterative implementation of the created concepts with continuous user engagement and rigorous software validation.
The Pediatric Growth Hormone Deficiency Patient Journey: Identifying Opportunities for Digital Health Interventions
Authors: Giunti Guido , Michelis Fulvio , Halabi Ammar , Koledova Ekaterina , Harvey Jamie , Dimitri Paul
Published: November 2024

Pediatric growth hormone deficiency (PGHD) is a chronic condition where the pituitary gland fails to produce sufficient growth hormone, leading to delayed growth and developmental challenges. Patient journey maps can provide insight into pain points and potential opportunities for new or improved interventions to enhance care. However, a patient journey map does not yet exist for PGHD. Secondary data analysis was performed on interviews and focus groups from five cohorts in Sweden, the United Kingdom, Luxembourg, France, and The Netherlands. Participants included 62 patients and caregivers who used a prototype digital health solution, which was used to guide discussions. Grounded theory was used to analyze the data, resulting in a patient journey map comprising six stages: awareness, diagnosis, treatment planning, treatment initiation, treatment maintenance and transition. This provides the first detailed PGHD patient journey map, revealing emotional sensitivities and challenges at each stage, and suggesting areas for targeted interventions to improve adherence and long-term outcomes.
Use Technology to Help Medical Staff Treat “New Health Problems” Arising Constantly
Authors: Karanikolas Nikitas N.
Published: November 2024

The development of medical science allows the treatment of more and more health problems that in the past were not a factor of consumption of health resources, because at that time medical science did not have protocols for their treatment. Health problems that are now treatable, hereafter referred as “new health problems”, often affect large population groups and require increased consumption of health resources. It therefore becomes necessary to increase the number of staff providing health services (doctors, nurses, etc.) and other resources. This raises the question: is it feasible to manage the “new health problems” by the existing medical staff? If not, are there other solutions? Could technology help the existing Medical Staff to sufficiently manage the “new health problems”? We will examine a pilot system “Recording and visualizing of outpatient monitoring data with smart mobile phones”, which seeks to ensure the competence of existing medical staff in the effective treatment of the ever-increasing volume of transplant patients.
ML-Based Framework to Predict the Severity of the Symptomatology in Patients with Post-Acute COVID-19 Syndrome
Authors: Nitulescu Adina , Crisan-Vida Mihaela , Tudoran Cristina , Stoicu-Tivadar Lacramioara
Published: November 2024

The paper describes a cohort of patients with post-acute COVID-19 syndrome, evaluated for the first time between week 3 and week 12 from the onset of symptoms following the acute COVID-19 infection. The patient’s baseline clinical features were used as predictors. The analysis showed that older patients with comorbidities are at higher risk of developing more long-lasting post COVID-19 symptoms. Further integration with a personal monitoring device and combination with the Fast Healthcare Interoperability Resources extends the standardization, interoperability and possibility of integration and harmonization with other hospital systems. By employing advanced machine learning techniques, insights can be derived and further examined to improve the outcome and early treatment options for patients.
Visualising Paths for Exploratory Search in the Health IT Ontology
Authors: Höffner Konrad , Brunsch Hannes Raphael , Jahn Franziska , Winter Alfred
Published: November 2024

Due to a lack of systematisation and unbiased information, finding the optimal combination of software products for health information systems is a challenging endeavour. We present a novel approach to visually explore the domain of application systems and software products for health care along the paths of the Health IT ontology (HITO). We present an algorithm and implementation in a web application that is freely available at the HITO website and licensed under the open source MIT licence. In comparison to other approaches of path-based exploration of knowledge graphs, the novelty of our approach is the use of path finding on the ontology level and combining this both with the instances of the classes along the chosen path as well as search filters to limit the search space. Our approach can be adapted to other domains where users with complex information needs interact with ontologies and knowledge graphs and can be supported by generative artificial intelligence in the future.
Clinical Informatics Foundations of 57 Years Sentinel and Genomic Surveillance: Data Quality, Linkage and Access
Authors: de Lusignan Simon , Joy Mark , Zambon Maria
Published: November 2024

Sentinel surveillance networks are sophisticated health information systems that warn about outbreaks and spread of infectious diseases with epidemic or pandemic potential, the effectiveness of countermeasures and pressures on health systems. They are underpinned by their ability to turn data into information and knowledge in a timely way. The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) is one of Europe’s oldest. We report its progressive use of technology to improve the scope of sentinel surveillance, with a focus on genomic surveillance. The technologies include terminologies, phenotypes, compute capability, virology including virial genome sequencing, and serology. The RSC’s data collection developed from partial, then full extraction of computerised medical record (CMR) data. with increasing sophistication in its creation of phenotypes. The scope of surveillance in 1967 was clinical diagnosis, influenza-like-illness (ILI) was its focus. In the 1992-1993 winter virology sampling started, with progressively more sophisticated sequencing of the viral genome. From 2008 viral sequencing was comprehensive with the Global Initiative on Sharing All Influenza Data (GISAID) the primary repository, supplemented by the COVID-19 Genomics UK (COG-UK) consortium in-pandemic. High quality primary care data captures sociodemographic features, risk group status, and vaccine exposure; linked hospital and death data informs about severe outcomes; virology identified the causative organism and genomic surveillance the variant. Timely data access and analysis will enable identification of new variants resistant to vaccination or other countermeasures and enable new interventions to be developed.
Using the German National Medication Plan for Clinical Studies in Practice-Based Research Networks
Authors: Schmutz Patrick , Krauss Arthur , Dörflinger Sven , Becker Arndt , Polanc Andreas , Salm Claudia , Peters-Klimm Frank , Hübner Gudrun , Erhardt Christian , Thies Christian
Published: November 2024

The German National Medication Plan (GNMP) can be a valuable and interoperable data source for clinical studies, due to its digital specification and mandatory provisioning for chronically ill patients. Digital transfer of a patients current GNMP from the Patient Data Management System (PDMS) into electronic case report forms would avoid error prone manual data capturing. It is also essential for studies in practice-based research networks (PBRN), where data capturing must have as little impact as possible on everyday practice. The following issues are currently preventing seamless digital integration: There is no standardized interoperable export of the GNMP from PDMS. In the current form, pharmaceutical catalogs are needed to decode the contained pharmaceutical registration numbers. As accessibility to the pharmaceutical catalogs is restricted, there is no generic access to the actual information needed for study data evaluation. In order to conduct studies, feasible workarounds for these issues had to be implemented in the standard operating procedures, tools and participating GP practices. To overcome the GNMP’s current lack of digital interoperability, the proposed solution combines semi-automated data export from PDMS at the GP practice and manual database search at the study center with a semi-automated processing pipeline to balance workload between GP practices, study management and evaluation.
Suitability of the OMOP Common Data Model for Mapping Datasets of Medical Research Studies Using the Example of a Multicenter Registry
Authors: Kurtz Milla , Winter Alfred , Löbe Matthias
Published: November 2024

Common Data Models (CDM) are developed to solve integration problems that arise in the secondary use of health data. The OMOP CDM is such a model that is mainly used for healthcare data, so this paper examines whether it is also suitable for mapping research data. An exemplary research dataset is mapped to the model and the model is tested for suitability. For this purpose, an ETL process is first designed with the OHDSI tools and finally implemented with Talend Open Studio for Data Integration. The data quality is checked, and the mapping and the model, together with the tools, are evaluated. Overall, all but three data fields from the source dataset could be mapped to the OMOP model, so that the model’s suitability for research data can be confirmed.
Enhancing Arden-Syntax-Based Clinical Reasoning with Ontologies
Authors: Grob Moritz , Kainz Jakob , Csarmann Andreas , Rappelsberger Andrea , Adlassnig Klaus-Peter
Published: November 2024

We present a new methodological approach based on integrating Arden-Syntax-based clinical decision support (CDS) with an upstream ontology service. Incoming linguistic patient data, such as single reports about detected germs or viruses, shall be identified by the applied ontology at a low level. Then, higher-level concepts are activated by ontology-based bottom-up reasoning. Access to these high-level concepts is then provided by Arden-Syntax-based CDS. The results suggest promising directions for future enhancements in knowledge-based artificial intelligence.
A Novel Taxonomy for Navigating and Classifying Synthetic Data in Healthcare Applications
Authors: van Dijk Bram , Islam Saif ul , Achterberg Jim , Muhammad Waseem Hafiz , Gallos Parisis , Epiphaniou Gregory , Maple Carsten , Haas Marcel , Spruit Marco
Published: November 2024

Data-driven technologies have improved the efficiency, reliability and effectiveness of healthcare services, but come with an increasing demand for data, which is challenging due to privacy-related constraints on sharing data in healthcare contexts. Synthetic data has recently gained popularity as potential solution, but in the flurry of current research it can be hard to oversee its potential. This paper proposes a novel taxonomy of synthetic data in healthcare to navigate the landscape in terms of three main varieties. Data Proportion comprises different ratios of synthetic data in a dataset and associated pros and cons. Data Modality refers to the different data formats amenable to synthesis and format-specific challenges. Data Transformation concerns improving specific aspects of a dataset like its utility or privacy with synthetic data. Our taxonomy aims to help researchers in the healthcare domain interested in synthetic data to grasp what types of datasets, data modalities, and transformations are possible with synthetic data, and where the challenges and overlaps between the varieties lie.
Fundamental issues of integration of innovative solutions
Authors: VITIV BOHDAN
Published: November 2024

Для обеспечения глубокой и всесторонней защиты инновационных технических идей от бесконтрольного заимствования и даже копирования , неочевидность идеи для среднего специалиста в технологическом поле возникшей идеи имеют сегодня в условиях всё более углубляющейся глобализации огромное значение Это значение ещё более усугубляется в связи с конкретным и комплексным развитием идеи и её постепенным пошаговым переходом от чисто идеи к конкретным взаимосвязанным техническим решениям и их интегративным проникновениям и технологической диффузии из одного технологического поля в другие смежные технологические поля , при этом базовым условием такого проникновения является смещение границы между технологическими полями и размывка признаков и свойств такой границы В качестве примера возникновения и синтезирования такого рода инновационной идеи , автор настоящей публикации приводит , развитый от идеи бесконтактного дистанционного контроля и он-лайн мониторинга параметров и концентраций технологического раствора принцип конструкции и алгоритм применения сенсора – капсулы до серийного производства такого рода сенсоров – капсул и их масштабного применения в условиях современного сложного высокотехнологического производства и для такого же применения в биологических -технологиях , медицине и сельском хозяйстве ; 1 Тут автору представляется необходимым некоторое отступление для анализа макро и микро вариантов развития и применения этих технологий в специфике конкретного разномасштабного применения и разномасштабных условий такого применения в условиях современного умного производства ;
Innovative Composite Materials Based on Graphite in Smart Home Parts;
Authors: VITIV BOHDAN
Published: November 2024

В наиболее эффективных электрохимических реакторах , разработанных в рамках различных программ по созданию в инфраструктуре умного дома систем очистки и регенерации технологической воды без применения химических реагентов , ткани из углерод углеродных композитов , обеспечивают практически все преимущества перед другими альтернативными технологиями ; Название этих тканей Этан и Хортица и они являются инновационным продуктом предприятия УКРУГЛЕКОМПОЗИТ из города Запорожье , Украина ; Учитывая тот необычный эффект , который приобретает электрохимический реактор при использования этих композитных тканей в качестве электродов и контактных систем для электродов, можно сделать предварительный вывод о том , что возможно эти материалы в своё время не были достаточно исследованы и квалифицированы на предмет их соответствия критериям наноразмерного – композитного материала ; Эти материалы применяются уже более 10 лет и постоянно открываются их всё более интересные свойства и качества и , при этом в научных публикациях появляется всё больше сообщений о работах по развитию композитных материалов из углерода и его модификаций ; Практический опыт в непроизводственных областях показывает , что и здесь имеется громадный резерв в целевом и эффективном применении такого рода материалов , как например в технике золочения при реставрации ; 1 Применение этих материалов позволяет избавиться от многих застаревших проблем , в частности , - проблем , связанных с краевым эффектом в электродных ячейках электрохимических реакторов ; Учитывая исключительный эффект от комплексного применения этих материалов , учёные и исследователи продолжают поиски
Changes in Romanian education during the Great Transition period: Focusing on education law
Authors:   United European Research Society, OUM Tae Hyun
Published: November 2024

This study aims to examine the changes and problems experienced in the field of education in Romania, which experienced two major inflection points: transition from communism to capitalism and integration into the EU. For this purpose, I analyzed changes in educational laws that occurred at major historical inflection points. First, to find out the educational situation before the significant transition period, I studied Romania's first modern education law, established during the reign of AL. I. Cuza in the mid-19th century. This law was very innovative, but it has not been effective due to much controversy. The education laws of the communist period were initially greatly influenced by the Soviet system, and the education laws of the late 1960s, when anti-Soviet policies began to be adopted, can be seen emphasizing military and technological independence. In the education law after the transition, we can see that Romanian society began to abolish the Soviet system and communist ideology. After joining the European Union, Romania revised the education law again for integration with Europe from an institutional perspective. Romanian education in the transition period can be seen as pursuing integration in diversity by restoring European values that had been interrupted during the communist period and, at the same time, finding Romanian deals within Europe. However, after the transition, several indicators related to Romania's education appear to be relatively low compared to OECD and EU countries, requiring qualitative improvement. The recent budget increase in the education sector is an appropriate response to this.
The Brussels Effect: Analyzing the EU's Carbon Border Adjustment Mechanism (CBAM), Battery Regulation and Artificial Intelligence Act
Authors:   United European Research Society, Shim Soyeon
Published: November 2024

This study is based on the premise that the EU's normative power does not provide the EU with hegemonic position, but rather acts as a soft power that leads to greater solidarity with countries that share the EU’s values. To this end, we first examine the Brussels effect, which provides global hegemonic status as defined by Bradford, from the perspective of normative power theory, and then examine the five preconditions for the Brussels effect to work and the factors that make it difficult for the Brussels effect to be sustained.
In contrast to previous research, this study considers “strengthening solidarity with value-sharing countries through the EU's normative power” as a characteristic of the Brussels effect and explains that the internal EU dimension of the Brussels effect, such as deepening European integration, which is often overlooked in Bradford's definition of the Brussels effect, has a mutually reinforcing relationship with the external dimension of the Brussels effect, which functions as a regulatory power over third countries. It then uses three recent examples of EU legislation (the Carbon Border Adjustment Mechanism, the Battery Regulation, and the Artificial Intelligence Act) to demonstrate that the Brussels Effect involves the strengthening of solidarity among countries with shared values through EU regulatory legislation.
In order to sustain the Brussels effect, this study borrows from Jürgen Habermas's communication theory to emphasize the importance of dialogue and debate between actors in the regulatory policymaking process and suggests creating more open channels of communication between value-sharing countries. To this end, this study proposes extending access to IPEX, an online platform for inter-parliamentary cooperation within the EU, to third country parliaments that share values with the EU, and bringing diverse actors into the EU regulatory legislative debate.
De Gaulle and European Integration, 1958-1969: between Anti-European and Realist
Authors:   United European Research Society, Shin Jong-Hoon
Published: November 2024

While leading the European integration process in the 1960s, General de Gaulle attempted to change the direction of European integration from the goal of a supranational federation to the goal of a confederation of intergovernmental cooperation. De Gaulle's European politics were one-sided and self-righteous, and it was not easy to obtain the consent of other member states. As a result, European integration in the 1960s led to a series of tensions and crises. The crisis took on various forms, including the failure to create a political union through the Fouchet Plan, the rejection of Britain's accession the European Economic Community twice, and the empty chair crisis. The purpose of this article is to explain de Gaulle's European politics and examine the impact of his European politics on the history of European integration.
The role of systematic training and advanced training of specialists in the formation of sustainable profits and competitive advantages of manufacturing companies
Authors: Vozianova N. Y. , Voiteleva T. M.
Published: November 2024

The article is devoted to the analysis of the impact of systematic training and advanced training of personnel on the formation of sustainable competitive advantages and growth of financial indicators of agro-industrial companies. Based on a multi-level analysis of empirical data obtained during a survey of 512 managers and HR managers of agricultural enterprises, a comparative analysis of the economic performance of organizations with different levels of investment in human capital development, as well as a series of in-depth interviews with top managers of 20 leading agricultural holdings, the authors come to the conclusion about the key role of corporate training in ensuring the long-term competitiveness and financial sustainability of agribusiness. The most effective methods and formats of training are identified, practical recommendations are given for improving the human resource management system in the agro-industrial sector.
Impact of a science centre enrichment programme on elementary students' understanding of genetic inheritance
Authors:   , Dairianathan Lourdes Mary Anne
Published: November 2024

This is a study of 346 elementary students (aged 11-12) from five schools in Singapore who took part in a two-hour enrichment programme at a science centre. The study aimed to look at how an enrichment programme could be used to facilitate and complement the understanding of genetic inheritance – a topic in school science that is known to be difficult to understand.
Educational digital storytelling for character and citizenship education in a Singapore primary school: a design-based research study
Authors:   , Wu Jing
Published: November 2024

This study reports on a two-cycle design-based research in a Singapore Character and Citizenship education (CCE) primary classroom. Literature review suggests a constructive pedagogical approach in CCE learning, particularly dialogue-based learning integrated with everyday experience. In Singapore context, intervention studies are generally lacking. More studies are either policy studies or baseline research. There is a need for exemplary cases and development of design principles. Educational digital storytelling (EDS) was thus introduced. Five orientations were identified, and the reconstructive EDS was proposed for the context. An initial set of STORM (skills, thinking, options, reflection, and making) design principles were further distilled to inform the research design. Specifically, the study aims to answer three research questions.
Effectiveness of a Facebook intervention on physical activity behaviour: an integration of identity theory and self-determination theory
Authors:   , Yong Tze Woon
Published: November 2024

Obesity rates are rising worldwide and its associated health problems prompt the need to examine the problem beyond current practices, to use other perspectives to devise more effective physical activity interventions. Physical activity behaviour can be understood through self-determination theory. Current research on motivation suggested that physical activity behaviour has over the years transited from one that is intrinsic in nature to an externally regulated behaviour. At the same time, identity researchers also observed a change in human behaviour to be more fragmented because of technological changes in the society. This thesis puts together a literature review outlining the new environment that we operate in and how that has modified our behaviour from the perspectives of identity theory and self-determination theory. Studies based on identity theory, self-determination theory and combination of the two theories have shown that both theories can be integrated to address the gaps in physical activity intervention. As there are also limited studies on physical activity identity or exercise identity, its measurement, validity and reliability, there is a need to review the foundations of identity theory and develop an adequate, valid and reliable identity scale that can address physical activity behaviour. From an understanding of identity theory and self-determination theory, this thesis also examines the association between identity, self-determination and physical activity behaviour. Lastly, the thesis evaluates the effectiveness of a physical activity intervention through the integration and application of both theories. The thesis aims to understand the identity-motivational influences of physical activity behaviour through three studies.
Gastric perforation in pediatrics patients: A case report with management
Authors: Khare Atul Kumar , Singh Kirti , Namdev Harsh , Sharma Pramila
Published: November 2024

Gastric perforation is uncommon and life-threatening in infants and children. The mortality is up to 30–70%, and the most common cause is congenital gastric muscular wall defects. We reported the case of a 7-year-old boy from a rural locality of north India who presented in the emergency room with a chief complaint of fever for 15 days followed by abdominal pain associated with one episode of non-bilious vomiting and abdominal distention. The child had not passed stool for 3 days. On exploratory laparotomy, we found perforation of 0.5×0.5 cm at the anterior wall of the stomach near the pyloric region, more toward the lesser curvature of the stomach. The stomach, small intestine, and large intestine were loaded with pus flakes. Peritoneal lavage was done, and perforation was primarily repaired with Grahm patch omentopexy done. The patient was discharged on the sixth post-operative day without any complications. We concluded that gastric perforation in pediatric patients beyond the neonatal period may lead to fatal clinical outcomes, which causes a mortality rate of as high as 30%. Spontaneous great curvature of gastric wall perforation has the highest morbidity.
A case report of renal mucormycosis masquerading as lower ureteric mass
Authors: Paighan Nitin Madanrao , Sharma Umesh , Saini Abhishek
Published: November 2024

Isolated renal mucormycosis is rare. Its occurrence in immunocompetent patients is low. We present the case of a 45-year-old male presenting with flank pain and intermittent fever. On further evaluation, he was found to have a lower ureteric mass. Partial cystectomy and radical nephroureterectomy with pelvic node dissection were done. Histopathology was suggestive of mucormycosis. To the best of our knowledge, this is the only case presenting as a lower ureteric mass requiring partial cystectomy. Diagnosis of mucormycosis is challenging and requires a high index of suspicion.
The influence of growth retardation of heifers to yearling age on the milk productivity of cows
Authors: Polupan Yu. P. , Pryima S. V.
Published: November 2024

The purpose of the research was to analyze the impact of growth delays in repair heifers in different periods of the first year of rearing on the compensatory growth of heifers and subsequent productivity of cows. The research was carried out in the herd of the breeding farm “Agrofirma “Svitanok” LLC of the Mariinsky district of the Donetsk region, based on information on the growth, reproductive ability and milk productivity of 1126 cows of the Ukrainian Red and Black-and-White Dairy and Holstein breeds with a dated first calving during the years 2007–2020. Animals without growth retardation were included in the control group, and animals with growth retardation at the age of 0–3, 3–6, 6–9, and 9–12 months, respectively, were included in the four experimental groups. Average daily weight gain of heifers of less than 500 g was considered growth retardation. It was established that despite catching up in growth intensity during the first year of growing, heifers in groups with growth retardation do not have the necessary live weight for insemination in the optimal period (15–16 months), and are characterized by a correspondingly older (by 3.5...15.5 %) age of first calving, lower milk yield by 3.1...21.3 %, milk fat by 3.6...21.0 % and by 3,3...23.9 % – protein in 305 days of the first lactation. Losses in milk productivity continue in subsequent lactations by 8.8...18.5 % in milk yield, 9.1...21.7 % in milk fat output, and by 9.2...22.0 % in milk protein. Growth retardation during the period of intensive puberty at the age of six to twelve months has the most negative effect on productive characteristics. Therefore, growth retardation of repair heifers during the first year of breeding should be avoided. Heifers with the greatest growth retardation are not advisable to leave for herd repair.
The fatty acid composition of lamb makes it a valuable raw material for the meat processing industry
Authors: Mykolaichuk L. P. , Lesnovskay O. V. , Sanzhara R. A. , Pokhyl O. M. , Gutyj B. V. , Dochkin D. O. , Mylostyvyi R. V.
Published: November 2024

Lamb holds a significant position in the food industry due to its nutritional properties and diverse flavour profiles. It serves as a source of high-quality protein, vitamins, and minerals, making it a valuable food product. In recent years, there has been a growing interest in the fatty acid composition of meat, particularly concerning their impact on human health. The primary aim of this study was to evaluate the fatty acid composition of lamb meat produced from the crossbreeding of Romanov sheep with Hisar rams. To achieve this, the research involved producing ram lambs of two genotypes: Romanov × Romanov (control group) and Romanov × Hisar (experimental group). The fatty acid profiles of the meat were analysed using gas chromatography following standard extraction and methylation procedures. The study revealed that the meat of crossbred lambs contains a higher level of unsaturated fatty acids compared to purebred lambs. Specifically, the crossbred lambs showed an increase in oleic acid by 1.79 % (24.59 % vs. 22.80 %), linoleic acid by 0.54 % (3.63 % vs. 3.09 %), and gondoic acid by 0.32 % (0.76 % vs. 0.44 %) (P < 0.05). This enhancement contributes to improved meat quality. Among saturated fatty acids, the content of palmitic acid increased by 0.85 % (24.20 % vs. 23.35 %), while stearic acid rose by 0.34 % (21.55 % vs. 21.21 %) in crossbred lambs. The ratio of saturated to unsaturated fatty acids in the control group was 1.66, indicating a predominance of saturated fatty acids, whereas in the experimental group, this ratio was 1.55, suggesting an improvement in favour of unsaturated fatty acids. Moreover, the ratio of omega-6 to omega-3 fatty acids was 3.75 in the control group and 3.50 in the experimental group. Although both values are within the normal range, the slight decrease in the experimental group indicates a better balance between these fatty acids, which may be beneficial for health. These results highlight the significance of selective breeding strategies for enhancing the nutritional value of meat, which is crucial for both producers and consumers. Future research could focus on further optimising crossbreeding methods to increase the beneficial fatty acid profiles in lamb meat, exploring the impact of different diets on fatty acid composition, and assessing consumer preferences related to meat quality attributes.
Humoral and cellular components of the natural defense system in limousin cows of different breeding lines
Authors: Zelinka M. P. , Fedorovych Ye. I. , Mazur N. P. , Suprovych T. M.
Published: November 2024

The problem of animal resistance has recently become increasingly important as the genetic potential of newly developed dairy cattle breeds has increased, and the animals are highly susceptible to various diseases, metabolic disorders, and disruptions in general homeostasis. This contributes to a significant culling of cows, prevents their planned selection, and, in turn, slows down the pace of breeding work. The state of natural resistance in animals is determined by nonspecific protective factors of their organism, which depend on several factors: species, breed, physiological state, conditions of care, housing, feeding, individual and constitutional characteristics, etc. The research aimed to study the natural resistance of Limousin cows of different selections. The studies were conducted at Lvivske LLC, Lviv region, on Limousin cows of Hungarian, Polish, and Ukrainian breeding. The natural resistance of the controlled animals was studied by analyzing the complex cellular and humoral blood factors in the third month after calving, according to the methods described in the reference book Laboratory Research Methods in Biology, Animal Husbandry, and Veterinary Medicine. It was found that Limousin cows of domestic and imported breeding differed in terms of natural resistance. In particular, the phagocytic activity of blood neutrophils, the phagocytic index, the phagocytic number, and the lysozyme and bactericidal activity of blood serum were highest in cows of Ukrainian breeding. However, their superiority in these traits over Polish and Hungarian breeding animals was statistically insignificant in almost all cases. A slightly higher level of protective functions in animals of the Ukrainian Limousin breed is also indicated by a higher number of T-lymphocytes, including T-helper cells. On the other hand, the number of T-suppressors was lower in Ukrainian cows by 3.1 % and 1.4 %, respectively, compared to Hungarian and Polish breeding animals. The immunoregulatory index in the controlled cows, depending on their country of breeding, ranged from 1,85 to 2,74, with the highest value observed in domestically bred individuals and the lowest in animals imported from Poland.
Productivity of pigs grown on the feed additive “Kormocid”
Authors: Ogorodnichuk H. , Zagamula Y.
Published: November 2024

Feed acidifiers (organic acids, inorganic acids, salts) are used in animal husbandry to reduce the pH level of the gastrointestinal tract, increase the digestibility of feed nutrients, and protect the digestive system from the penetration and spread of pathogenic bacteria. Our research aimed to experimentally study the influence of the feed acidifier “Kormocid” on the intensity of growth of crossbred piglets during rearing and establish the optimal dose of the additive. The effect of feeding the feed acidifier “Kormocid” on the live weight of growing pigs was experimentally investigated. The experiment was carried out on four similar groups of pigs on the growing farm, 14 heads in each, obtained from crossing sows of the large white breed with boars of the landrace breed. Experimental groups of pigs were formed, taking into account origin, live weight, age, and article. The control group of pigs consumed the main ration – full-ration combined feed TM “Tsekhavit” during the equalization and main periods. In addition to the main diet, the experimental groups were fed different doses of the feed additive acidifier “Kormocid.” The comparative and main experimental periods were 10 and 45 days, respectively. The researched feed additive-acidifier “Kormocid” is produced by SE “Enzym,” Ukraine. This high-quality acidifier is based on 5 organic acids (formic, propionic, lactic, citric, ascorbic). The organic acids in the finished product are at least 50 %. Experimentally, it was established that the addition of the acidifying feed additive “Kormocid” to the complete diet of growing pigs at a dose of 1.0 kg/1 t of compound feed can increase the live weight and absolute growth of animals by 1.88 kg or 5.7 %, respectively, and by 2.0 kg or by 7.9 % kg, and increase average daily gains by 44.45 g or by 7.9 %. Feeding growing pigs with the acidifying additive “Kormocid” at a dose of 1.0 kg/1 t of a compound feed helps increase piglets' growth energy by 4.62 %. The use of the feed additive acidifier “Kormocid” during the growing-up period of pigs allows for the reduction of the cost of feed per unit of growth and increases the payment of feed per increment.
Recreational potential and landscape attractiveness of the conservation areas
Authors: Paranjak R. P. , Kropyvka S. J. , Gutyj B. V. , Hradovych N. I. , Lytvyn N. A. , Varshavska I. А.
Published: November 2024

The recreational potential of the objects of the natural reserve fund of the territory is a critical element of sustainable development aimed at preserving natural resources and improving the quality of life. The importance of developing such potential is due to the need to preserve natural areas for ecological purposes and their use for recreation against the background of growing anthropogenic transformation of the environment. In Ukraine, in particular, in the Lviv region, the development of the network of nature-protected areas, which actively began at the end of the first decade of the 21st century, slowed down significantly, not reaching the desired level of protection, and now it has practically stopped due to several objective reasons, including the impact of the war even on those regions where hostilities are not taking place. In the future, it is advisable to answer how realistic it is to achieve the declared indicators of the protected area, which exceed the current ones almost twice. At the same time, we will consider two circumstances: the existing state of the network of protected and nature-protected territories and their suitability for recreation according to the criterion of attractiveness. Since there are different models of the organization of ecologically stabilizing territories, when planning the region's development, optimal trajectories of the development of the nature reserve fund structure should be predicted based on the existing one. In this context, this work focuses on classifying PZF objects, analyzing their features, and the landscape characteristics of institutions of the Lviv region that provide recreational services. On the other hand, attention is paid to the study and comparison of approaches to the assessment of the attractiveness of the territories of the nature reserve fund with an emphasis on the diversity and attractiveness of their landscapes.
Comparison of Rapid Typhidot Test Based on Sanitation Environment in Healthy Individuals in Medan
Authors: Robby Awaluddin Perangin-Angin  , Rina Amelia  , Jelita Siregar
Published: November 2024

Typhoid fever is a gastrointestinal tract infectious disease frequently found endemic in Indonesia, which can be transmitted by oro-fecal from food or water contaminated directly or vector carries these bacteria. Medan Belawan subdistrict has a high rate of diarrhea cases and a low percentage of a health-house model. Otherwise, the Medan Petisah subdistrict has fewer diarrhea cases and a high percentage of the health-house model. This study was aimed to compare the presence of antibodies from the Typhidot Test in people living in poor and healthy sanitation conditions. This study is an observational study with a cross-sectional design. The population is all people around Medan Petisah and Medan Belawan health center. All data were calculated using SPSS and analyzed with Chi-Square and Regression Logistics tests. The result indicates no significant association between the presence of IgM and IgG from the results of the Typhidot test on environmental sanitation in Medan (p>0.05). Thus, it can be concluded that Sanitation conditions did not affect the formation of IgM and IgG against Salmonella Typhi bacteria.
Contextualizing primary school teachers’ perception of the parent-child relationship
Authors: Saragih Erikson , Hashim Haida Umiera , Junaid Ayesha , Nababan Tiarnida , Nababan Tiorika Mariana
Published: November 2024

The most crucial relationships for students' social and emotional development and wellbeing are those between parents and pupils. While there is a wealth of research on programs to enhance parent-child connections, few are designed for use by educators in early education and care settings. This study aims to describe teachers' comprehension of the parent-child relationship concerning social and emotional development, the teacher's role in fostering the parent-child relationship, and the forms of teacher support in the parent-child relationship. This research method is a qualitative descriptive study with a phenomenological design involving six school principals and twenty teachers at the elementary education level as research subjects. The results showed that early education teachers were reluctant to contact parents, although acknowledging the importance of parent-child interactions. Teachers tended to be unwilling to impart their knowledge to parents since it was primarily implicit and derived from observations and real-world experiences. Teachers want theoretical, supported evidence methods to deepen their understanding and enhance everyday activities that strengthen parent-child interactions. The results are crucial for creating a parent-child connection program led by educators for implementation in educational and childcare facilities. A comprehension of educators' regular practices, their function in promoting parent-child connections, and children's social and emotional development should be explored to guide the creation of an educator program. These results are crucial for creating a parent-child connection program developed by educators for use in educational and childcare settings.
СОЦІАЛЬНА ПІДТРИМКА ЗДОБУВАЧІВ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ У ПРОЦЕСІ ДИСТАНЦІЙНОГО ВИВЧЕННЯ ІНОЗЕМНИХ МОВ
Authors: ШАПОШНИКОВА Ірина , ГОШТАНАР Ірина
Published: November 2024

Основним завданням соціальної роботи у закладах вищої освіти є підтримка соціальної інтеграції, покращення психосоціального клімату у закладі освіти та формування сприятливого середовища для всебічного розвитку студентів. Напрямами покращення ефективності соціалізації є врахування особливостей кожного окремого студента та різних груп студентів (іноземних студентів, студентів з особливими освітніми потребами, соціально незахищених, пільгових категорій), моніторинг і зворотній зв’язок, психологічна підтримка, надання інклюзивних послуг, співпраця зі стейкхолдерами та потенційними роботодавцями. Виокремлено основні напрями покращення ефективності соціальної роботи зі здобувачами закладу вищої освіти: індивідуальний підхід, моніторинг і зворотній зв’язок, розширення можливостей психологічної підтримки, вдосконалення інклюзивних послуг розширення практик наставництва, створення центрів розвитку кар’єри та працевлаштування. Важливу роль у соціальній роботі зі студентами відіграє постійна взаємодія різних служб і підрозділів, а саме: залучення психологічної служби, юридичної служби, гуманітарного відділу та центрів кар’єри забезпечує узгодженість всіх дій щодо допомоги та підтримки студентів. Виокремлено ключові аспекти соціальної роботи зі здобувачами закладів вищої освіти під час навчання іноземних мов, а саме: адаптація студентів-початківців до нового освітнього середовища, психологічна підтримка, соціальна інтеграція, волонтерство і міжнародні проєкти, допомога у навчанні, кар’єрні консультації, культурна адаптація, медіація та підтримка. З’ясовано, що для адаптації навчальних матеріалів та методів навчання до дистанційного формату усі навчальні ресурси мають відповідати вимогам доступності. Інтерактивність та гейміфікація виступають як технології ефективного навчання іноземних мов.
ФОРМУВАННЯ КАРТОГРАФІЧНОЇ КУЛЬТУРИ ЗАСОБАМИ НУМІЗМАТИЧНОЇ ГЕОГРАФІЇ У ШКІЛЬНОМУ КУРСІ «УКРАЇНА У СВІТІ: ПРИРОДА, НАСЕЛЕННЯ»
Authors: Байтеряков Олег Зуфарович
Published: November 2024

Статтю присвячено виявленню методичних підходів до застосування пам’ятних і ювілейних монет України у шкільному курсі «Україна у світі: природа, населення» для формування у здобувачів загальної середньої освіти картографічних знань і вмінь. Висвітлено значення монет як засобів нумізматичної географії і як засобів навчання географії. Наведено детальні методичні рекомендації з використання монет України під час вивчення таких картографічних проєкцій, як азимутальна нормальна, азимутальна поперечна й азимутальна коса, додатково проєкції Ван дер Ґрінтена. Проаналізовано географічний зміст таких монет України, що містять картографічні зображення: «10 років антарктичній станції «Академік Вернадський»», «50 років Організації Об’єднаних Націй», «165 років Астрономічній обсерваторії Київського національного університету», «Володимир Корецький», «Учасникам бойових дій на території інших держав», «100 років світової авіації та 70-річчя Національного авіаційного університету», «Перший пуск ракети-носія «Зеніт-3SL”». Під час опрацювання зазначених монет здобувачам пропонується визначити проєкцію зображеної карти, охарактеризувати її властивості, пояснити вибір проєкції саме для цього дизайну, а також додатково стисло зупинитись на тематиці монети та наявних зображеннях географічних об’єктів або явищ. Запропоновані завдання на підставі цих монет призначені для закріплення навичок роботи з географічними координатами. Наведено приклади встановлення внутрішньопредметних і міжпредметних зав’язків. Приділено увагу виявленню на окремих монетах картографічних помилок, зокрема розташуванню материків і окремих об’єктів щодо географічної сітки на карті. Виявлено монети, що містять цікаві варіанти карти Європи й України, які можна застосовувати для вивчення відповідних тем, а також монети, що мають зображення засобів орієнтування, геодезичних і астрономічних приладів і особливостей картографічних і геодезичних вимірювань. Продемонстровано практичне значення застосування засобів нумізматичної географії у шкільному курсі географії.