bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Produced Water Quality Discharge into the Sea by Using Hungry Bacteria
Authors: Pedenaud Pierre , Baldoni-Andrey Patrick , Breton Audrey , Segues Bertrand , Demangel Anne , Jacob Matthieu
Published: April 2018

The technology consists on using microorganisms in biofilm in order to remove the toxicity of produced water, at low cost with a low footprint for offshore sites.

For a long time, the concentration of oil-in-water was the unique specification for water disposal into the sea. With a new European regulation and worldwide evolution, the environmental performance includes also the demonstration of toxicity removal close to the production site.

Worldwide, the quantity of produced water is increasing continuously year after year of production. Even if produced water reinjection is the favorite option within TOTAL, a large part of produced water is still released into the sea.

The technologies, currently implemented offshore, are not always sufficient to comply with this regulatory evolution: suspended hydrocarbons are well treated but dissolved compounds are not. Biological treatment can reduce the toxicity of wastewater as it will biodegrade organic pollution such as phenols, mono or Poly Aromatic Hydrocarbons. But the size of conventional biotreatment equipments is not compatible with the offshore constraints.

Among biotreatment systems, a technology called MBBR (Moving Bed Biofilm Reactor) which involves bacteria organized in biofilm attached to supports, demonstrated a strong robustness compared to conventional activated sludge. The size reduction of equipments induced by MBBR has never been evaluated on saline produced water.

Lab trials demonstrated the potential of biodegradation for saline water. The team wanted to reduce the size of equipments by dividing by at least 20 the residence time of the bioreactor.

Lab experiments with supported biomass demonstrated the efficiency of the system on produced water containing up to 15% of salinity. The ecotoxicity measured on sensitive species was removed and the concentration of hydrocarbons was drastically reduced (<3 mg/L).

The experimental pilot (0.5-4 m3/h) was operated for 10 months until May 2017 in South West of France on a production site. With only 30 min residence time, the toxicity was reduced by 85% where usual biotreatments require 24 hours of residence time.

The pilot is equipped with a final step including membrane filtration with reverse osmosis in order to demonstrate the feasibility of desalination for water reuse.

The technology is the first compact biological treatment. Stakes are huge. For a flowrate 20000 bpd, the investment cost for a TOTAL site offshore is today close to 40M$. This cost is estimated at 10M$, the footprint is divided by 3 and the weight reduced by 2 compared to extraction process. It is now possible to implement a biotreatment offshore.
Human Error - Fresh Thinking for Managing Non-Compliant Behaviors
Authors: Bridle Peter V.
Published: April 2018

1912. The RMS Titanic steams toward a known ice field while maintaining close to full speed…

1986. The Challenger space shuttle takes off despite a known problem with a critical component requiring NASA to circumvent and by-pass its own safety rules to make the launch time.

1987: The "Herald of Free Enterprise" a roll-on/roll-off car ferry leaves the port of Zeebrugge in Belgium with its bow door open. This is not an uncommon practice when ferry crossings fall behind schedule.

2005. Operators at the Texas City refinery routinely overfill a distillate column as part of normal start-up practices, even though this is seen as an unacceptable procedural violation.

2010. The offshore drillship "Deepwater-Horizon" is seriously behind schedule on the Macondo well and with ever rising operating costs, there is an immediate desire to finish the job. And while the crews have been congratulated for a "safe job", the same can't be said of key barriers to prevent catastrophic loss.

What do these all have in common? Simple… Human Error

Despite spanning almost a hundred years, in each and every case, the past experience of those involved conspired with an operating culture that had "normalized" elevated levels of risk. Any yet, when disaster stuck, it was met with utter disbelief and questions around how this could possibly have ever happened.
Bowtie Barriers - Adding Offense to Defensive Risk Reduction Models
Authors: Haydock Paul
Published: April 2018

Defensive risk reduction models are typically reactive elements. These can be improved by adopting offensive strategies that are reaching outwards to gather critical data to inform on barrier performance, and enhance improvements in advance of the next potential unwanted event.

Practical techniques to add strategies of offense to defensive barrier risk reduction models are available, through the capabilities of bowtie barrier management. These can be fully capitalized with systems and software at an enterprise level. Specifically, an offensive approach uses the ability to combine risk, audit, incident and maintenance system or barrier-state data onto bowtie barriers for a fourfold view of barrier condition. This enables a more offensive stance: predictions of barrier decay or weakness, followed by improvement strategies and follow-up.

A critical four-corned risk and incident reduction strategy is presented: Risk: What are the major risks in our organisation and how are we managing them?Audits: Is each barrier in place and maintained as required?Incidents: Across one or several incidents, what barriers have been involved, and did they fail or perform as expected?Systems: What systems and system components are degraded or offline today and which barriers are therefore affected?

Collation of this data can be performed by choosing a risk element that is common and available to all of the four elements – namely, a bowtie barrier. By using the visual aspects of a bowtie barrier to become the repository for all the relevant data, interpretation, indication and improvement is enhanced. Enterprise risk systems on suitable bowtie-based servers can bring all relevant data under one warehouse and improve access, consistency and shared risk reduction opportunities. Just as each barrier can become a hub for the capture and analysis of dynamic data, a server-based risk analysis warehouse for the enterprise promotes use of various forms of captured data for the scrutiny and improvement of barriers.
Moving from Conflict to Engagement with a Marginalised Community in Iraq Generates Mutual Trust, Improved Security and Business Continuity
Authors: Skerritt B. , Boyd C. , Al-Mudhaffar H. , McDonald J. , Roscoe A.
Published: April 2018

This paper will demonstrate that, instead of building higher security fences, the process of understanding marginalised and engaging with neighbouring communities is key to building relationships and neutralising hostility. It describes how the Rumaila Operating Organisation (the consortium), managing Iraq's largest oilfield - which generates 40% of the country's GDP - dealt with major unrest that forced the shutdown of operations. The situation was resolved by a sustainable community development program, based on thorough research and needs analysis.

The Rumaila oilfield must inject over 2 million barrels of industrial water/day by 2025 in order to continue producing 1.4 million barrels of oil/day. In 2013 construction to achieve this increased capacity from the Qarmat Ali Water Treatment Plant was halted for six months by gunfire, stone-throwing, violence and intimidation by the neighbouring community. They harbour a deep mistrust of outsiders; Saddam Hussein drained their marshes and persecuted them. A new approach was needed and Sheiks representing warring factions within the community were brought together by the organisation for the first time to identify the community's concerns and needs.

The new engagement approach was aimed at building mutual respect and trust, initially via the women, with these wary communities. This entry centres on stakeholder analysis and relationship-building in southern Iraq, which has significant security challenges, and how previously warring tribes are now coming together in the ‘Beautiful Game’ of football. The activities of 2013-15 laid the foundations for community engagement, while the period 2015-17 sought to reinforce these relationships together with a focus on delivering Social Investment projects centred on health, education, sport and recreation as part of the Rumaila Social Welfare Fund. The engagement and investment work undertaken by the consortium is also intended to support a number of the United Nations Sustainable Development Goals1 in respect of community development and equity.

In addition, while community unrest was the catalyst for a root and branch review of community relations in Qarmat Ali, during this later period the consortium proactively engaged with villages in North Rumaila – communites that also neighbour the oilfield, and with similar social issues and challenges as Qarmat Ali. But here, the engagement wasn't prompted by community protest, rather by a systematic review and assessment of stakeholders and their relative needs.
Challenges and Effective Strategy for Managing Occupational Health and Industrial Hygiene at Onshore Remote Environments of Garraf, Iraq Operation
Authors: Badzri Shairizal B , Bakar Ahmal Kamal , Clare Vanessa
Published: April 2018

Working in remote oil and gas operations of PETRONAS Carigali Iraq Operation in Garraf, Iraq presents a multitude of health challenges including significant delays to medical diagnosis and treatment.

In addition, remote areas like Garraf are susceptible to significant environmental exposures, predominantly risks of communicable diseases with limited access to basic necessities, extreme temperatures during summer (up to 55°C); limited medical expertise and communication as well as security threats. These factors further post risks to personnel working in the area to suboptimal medical care – including unnecessary and delayed medical evacuation (MEDEVAC) as well as suboptimal care during transport.

This paper describes the challenges faced at Garraf Operations as well as the Occupational and Industrial Hygiene (OH/IH) strategies adopted to minimize and manage associated risks. Planning and preventive controls discussed in this paper includes but not limited to, fitness to work, fatigue management, heat stress management, food and water hygiene, health and wellness programmes as well as substance misuse programme. Proactive and comprehensive identification of a country's limitations is essential in determining the most effective and efficient recovery plan. Additionally, site location, situational factors as well as thorough Health Risk Assessment shall be considered when establishing Medical Emergency Response Plan (MERP).

In short, plans and strategies adopted by PETRONAS Carigali Iraq Operations in managing OH/IH challenges could be replicated and/or referenced as lessons learnt when operating in remote locations.
Comparativo farmacológico de tratamento de dislipidemias em crianças, diabéticos, HIV-positivos e idosos
Authors: Reinaldo Ricardo Persona , Cardoso Gleidson
Published: April 2018

Introdução: O estudo aqui apresentado fundamenta-se na associação de drogas para controle da dislipidemia em crianças, diabéticos, HIV-positivos e idosos. Objetivo: Discorrer acerca das dislipidemias sob o panorama dos fármacos de melhor escolha fazendo um paralelo entre os achados bibliográficos quanto a eficiência entre as principais drogas utilizadas no tratamento das dislipidemias. Material e Método: O presente estudo trata-se de levantamento bibliográfico sobre o tema através de achados de artigos científicos e demais materiais técnico-científicos. Resultados e Conclusão: Em crianças pode-se indicar a droga Ezetimibe como alternativa de vanguarda para o tratamento das mesmas, de forma que existem contraindicações neste grupo principalmente do ácido nicotínico ou fibratos, ficando ainda as estatinas como uma droga de primeira escolha. Para pacientes diabéticos contra indica-se o ácido nicotínico e sequestrantes de ácido biliar, visto que ambos alteram o índice glicêmico. Indica-se nestes casos os moduladores SRAA e as estatinas de intensidade moderada. Em Idosos verificou-se que as estatinas compreendem o tratamento de primeira escolha para reduzir os níveis de LDL (Lipoproteína de Baixa Densidade) e produzir pequenos aumentos de HDL (Lipoproteína de Alta Densidade) com declínio modesto em TG (Triglicérides), reduzindo a probabilidade de doenças cardiovasculares. Lembrando que é aceitável nos estudos selecionados a associação de um fibrato a uma estatina. E por fim os pacientes HIV – positivos, notou-se que o uso do ciprofibrato, da rosuvastatina ou da combinação de ambos, sendo efetivo, seguro, e bem tolerado por estes indivíduos.Descritores: Dislipidemias; Terapêutica; Complicações do Diabetes; Criança; Idoso; Soropositividade para HIV.
Remoção cirúrgica de odontoma composto em maxila com achado tomográfico sugestivo de cisto do ducto nasopalatino
Authors: Lacerda-Santos Jhonatan Thiago , Granja Gélica Lima , Dos Santos Jalber Almeida , Araújo-Filho José Cadmo Wanderley Peregrino de , Freire Julliana Cariry Palhano , Dias-Ribeiro Eduardo
Published: April 2018

Os odontomas são lesões benignas, que se apresentam com maior frequência nos maxilares e são encontrados com rotina em exames radiográficos. São classificados em composto, complexo e misto. O presente estudo tem por objetivo relatar um caso sobre remoção cirúrgica de odontoma composto em região anterior da maxila de um paciente de 18 anos, do sexo masculino e também destacar um achado tomográfico de um possível cisto do ducto nasopalatino. O tratamento proposto foi a exérese da lesão em ambiente ambulatorial sob anestesia local, através de acesso envelope na região palatina e triangular em região vestibular. O paciente está em acompanhamento clínico radiográfico durante sete meses e não apresenta sinais de recidiva.Descritores: Cirurgia Bucal; Odontoma; Anormalidades Dentárias; Tomografia Computadorizada de Feixe Cônico.
Conscientização sobre hábitos relacionados ao sono no interior do estado de São Paulo
Authors: Corrêa Camila de Castro , Campos Leticia Dominguez , Weber Silke Anna Theresa
Published: April 2018

Introdução: Na semana do dia 15 de março, são realizadas ações pelo mundo para a conscientização sobre o sono. Para tal missão, a Associação Brasileira do Sono conta com a coordenação de um membro associado por cidade, responsável por organizar atividades na sua região. Objetivo: descrever as ações de promoção de saúde desenvolvidas nas cidades do interior paulista na semana do sono do ano de 2017. Métodos: Foram realizadas parcerias com universidades, hospitais, empresas e estabelecimentos comerciais para a realização de palestras com conteúdos gerais de higiene do sono, a influência das tecnologias de comunicação na qualidade do sono e conteúdos específicos do sono em trabalhadores de turno. Resultados: As palestras aconteceram nos seguintes locais: FEMSA Coca-cola, Bauru/SP, Faculdade de Odontologia de Bauru USP, Bauru/SP , Faculdade de Agudos FAAG, Agudos/SP, Universidade do Sagrado Coração USC, Bauru/SP, Faculdade Marechal Rondon, São Manuel/SP, Hospital das Clínicas – Faculdade de Medicina de Botucatu, Botucatu/SP, Hospital Estadual de Botucatu, Botucatu/SP,  Açaí da Barra / Avenida Getúlio Vargas, Bauru/SP, Caminhada do 2° movimento pro sono, Bauru/SP e Coca-cola Lençóis Paulista/SP.  Dessa forma, as ações abrangeram desde crianças, adolescentes, universitários e idosos de cinco cidades do interior paulista. Foram abordadas 489 pessoas diretamente, além da disponibilização de cartilhas extras nesses mesmos ambientes em áreas de grande circulação de pessoas. Conclusão: As ações do interior paulista ocorreram de modo abrangente, atuando na população universitária até com grupos de idosos. Sugere-se que ações como esta sejam replicadas, abrangendo número ainda maior de participantes, em diferentes regiões.Descritores: Sono; Promoção da Saúde; Exposições Educativas.
ANÁLISE DE FATORES PREDITORES DA PRÁTICA DO SEXO SEGURO NO GÊNERO FEMININO
Authors: Higuchi Agnaldo Keiti , Veiga Ricardo Teixeira
Published: April 2018

De acordo com as premissas da Lógica Dominada por Serviço, o valor é cocriado na integração de recursos de diferentes atores, e é definido pelo beneficiário do serviço. Entre esses recursos estão traços de personalidade que, se estimulados, podem levar a uma mudança efetiva de comportamento, como por exemplo, à adoção frequente de uso de preservativo. Após pesquisa bibliográfica sobre a cocriação de valor, elaborou-se modelo conceitual, baseado no Modelo 3M, que foi testado empiricamente junto à amostra de estudantes do sexo feminino dos cursos noturnos da Universidade Federal dos Vales do Jequitinhonha e Mucuri, na cidade de Teófilo Otoni-MG. Uma vez efetuada a coleta de dados via aplicação de questionários, a análise dos dados revelou que o traço de personalidade “número de interações”, ligado a ações em grupo, tem maior influência sobre a cocriação de valor que o traço “motivação para a saúde”, ligado a características individuais.
Microscopic mechanisms of soil moisture related to hydromulching
Authors: Jian Gu , Guanghua Yin , Ningning Ma , Zhan-xiang Sun , Xue Li , Shijie Wang , Xiaole Zhou
Published: April 2018

Hydromulching is a new mulch product which has positive effects on soil moisture conservation and the inhibition of evaporation. However, current research on its soil moisture conservation effect has mainly adopted the field fixed-point observation method, rather than revealing the soil moisture conservation mechanism from the microstructure of the hydromulching. This paper applied spectrum analysis technology to observe the structure and micromorphological features of hydromulching, which will be able to reveal the mechanism of soil moisture conservation. Three types of hydromulching, based on laboratory preparation, were used to analyze the mechanism of soil moisture, using the infrared spectrometer (FTIR) and environmental scanning electron microscope (ESEM). The results showed that −OH generates intermolecular hydrogen bonds between carboxymethylcellulose sodium (CMC) and polyvinyl alcohol (PVA); the hydrogen bonds were formatted between the molecules of the two components, strengthening their compatibility, which increased the effectiveness of the hydromulching and created a dense mesh structure. ESEM observation results showed that preparation 1's hydromulching coverage had good effects, while preparations 2 and 3 performed poorly. Therefore, we can conclude that hydromulching effectively cements soil particles. Then it can generate the soil membrane structure to reduce evaporation and improve soil moisture conservation function.
MicroRNAs in Atrial Fibrillation
Authors: Briasoulis Alexandros , Sharma Shikha , Telila Tesfaye , Mallikethi-Reddy Sagar , Papageorgiou Nikolaos , Oikonomou Evangelos , Tousoulis Dimitris
Published: April 2018

MicroRNAs (miRNAs) are small non-coding RNAs, involved in regulation of
post-transcriptional gene expression. They exert key role not only in physiology and normal
development of the cardiovascular system but also in cardiovascular disease development
and progression. Recent animal and human studies of tissue specific miRNAs
have suggested a role in structural and electrical remodeling in atrial fibrillation (AF).
Their emerging role as biomarkers and potential therapeutic targets in patients with AF is
discussed in this review.
DNA Fragmentation, Cell Cycle Arrest, and Docking Study of Novel Bis Spiro-cyclic 2-oxindole of Pyrimido[4,5-b]quinoline-4,6-dione Derivatives Against Breast Carcinoma
Authors: Mohamed Magda F. , Abdelmoniem Amr Mohamed , Elwahy Ahmed H.M. , Abdelhamid Ismail A.
Published: April 2018

Background:

Recently, it is reported that heterocycles containing pyrimidoquinoline
moiety show a broad spectrum of medicinal and pharmacological properties including anticancer,
anti-microbial, anti-inflammatory activities, analgesic and antiviral. In additions, spirocyclicoxindole
containing compounds represent an important class of compounds that exhibit wide range
of biological properties. The asymmetric chiral spiro carbon is considered to be the main criteria of
the bioactivities. Spirooxindole structures represent the main skeleton for various alkaloids and
pharmaceutically important compounds. Among them, the naturally occurring pyrrolidinylespirooxindole
alkaloid, horsifiline that exhibits anticancer activity against human brain cancer cell lines.

Objective:

The objective of this study is the synthesis of novel bis spiro-cyclic 2-oxindole of
pyrimido[4,5-b]quinoline derivatives and evaluate the anticancer activity of new compounds for
synergistic purpose. Different genetic tools were used in an attempt to know the mechanism of action
of this compound against breast cancer.

Method:

An efficient one pot synthesis of bis spiro-cyclic 2-oxindole derivatives of pyrimido[4,5-
b]quinoline-4,6-dione using 6-aminouracil, bis-isatin and dimedone has been developed. The cytotoxic
effect against different human cell lines MCF7, HCT116 and A549 cell lines was evaluated.
The derivative 6a, was found the most encouraging compound in this series and it was selected for
molecular studies against MCF7.

Results:

Our data indicated that compound 6a is an attractive target for breast cancer, as it inhibits
proliferation, cell cycle progression and induces apoptosis of tumor cells. This inhibition is mediated
by fragmentation of genomic DNA, up-regulation of [caspase-3, tumor suppressor gene p53, and
pro-apoptotic gene BAX], and down-regulation of anti-apoptotic BCL2 gene. In additions it caused
cell cycle arrest in S phase. This work provides an evidence of the potent effect of the new compound
6a and assists in the progress of new healing agents for cancer.

Conclusion:

We have developed an efficient method for the synthesis of novel bioactive bis spirocyclic
2-oxindole derivatives incorporating pyrimido[4,5-b]quinoline derivatives. Most of our new
derivatives give potent cytotoxic effect more than the standard drug Fluorouracil (5-FU) especially,
compound 6a which was the most active and promising one in this series against MCF7, HCT116,
and A549 cell lines.
Best Prophylactic Strategy in Groups at Risk of Intraoperative Floppy Iris Syndrome Development: Comparison Between Atropine Instillation and Adrenaline Intracameral Injection
Authors: Nuzzi Raffaele , Arnoffi Paolo , Tridico Federico
Published: April 2018

Background:

Intraoperative Floppy Iris Syndrome (IFIS) is an important cause of surgical complications and iris defects in patients undergoing phacoemulsification that were treated with selective subtype α1A receptor antagonists for a long period of time. To date, no definitive preventive strategy has emerged, yet. The need of prophylaxis is dictated by the high prevalence of males affected by benign prostatic hyperplasia undergoing cataract surgery.

Objective:

To identify the best prophylactic strategy in groups at risk of IFIS development by comparing two mydriatic treatments in course of phacoemulsification surgery.

Methods:

81 eyes of 81 patients in treatment with Tamsulosin were enrolled in the study. 43 eyes were treated with atropine sulfate 1% while 38 eyes received an injection of mydriatic solution containing epinephrine in the anterior chamber. All phacoemulsifications were videotaped in order to assess the occurrence of IFIS and the severity of the syndrome.

Results:

The treatment group showed a statistically significant reduction (p = 0.0115) of floppy iris syndrome incidence, from 86.05% (37/43) of the atropine group to 60.53% (23/38). The analysis showed a reduction of IFIS mild form only, whereas the incidence of severe forms remained unchanged.

Conclusions:

We believe that IFIS may arise through two different mechanisms: pharmacological antagonism and anatomical modifications. Patients suffering from mild forms of the disease showed a statistically significant reduction of IFIS incidence after intraoperative prophylaxis due to epinephrine’s ability to displace Tamsulosin, resulting in the increase of iris tone when the disease is caused mainly by receptorial antagonism. On the contrary, prophylaxis does not deliver any valuable result in case of severe forms where the anatomical variations play a major role.
Preventive Services Utilization Among Cancer Survivors Compared to Cancer-free Controls
Authors: Uhlig Annemarie , Uhlig Johannes , Strauss Arne , Trojan Lutz , Lotz Joachim , Hosseini Ali Seif Amir
Published: April 2018

Purpose:

To summarize the current evidence on preventive services utilization in cancer survivors.

Methods:

A systematic literature review and meta-analysis was conducted in February 2016. Studies were included if they compared the utilization of influenza vaccination, cholesterol/lipid testing, bone densitometry, or blood pressure measurement among survivors of adulthood cancer to cancer-free controls. Random effects meta-analyses were conducted to pool estimates.

Results:

Literature search identified 3740 studies of which 10 fulfilled the inclusion criteria. Cancer survivors were significantly more likely to utilize bone densitometry (OR=1.226, 95% CI: 1.114 – 1.350, p<0.001) and influenza vaccination (OR=1.565, 95% CI: 1.176 – 2.082, p=0.002) than cancer-free controls. No statistically significant differences were detected for blood pressure measurement and cholesterol/lipid testing (OR=1.322, 95% CI: 0.812 – 2.151, p=0.261; OR=1.046, 95% CI: 0.96 – 1.139, p=0.304).

Conclusions:

Cancer survivors were more likely to receive influenza vaccinations and bone densitometry. Future studies should evaluate underlying mechanisms and whether the utilization of preventive services translates into prolonged survival of cancer survivors.

Implications for Cancer Survivors:

Our meta-analysis demonstrated cancer survivors to be more likely to receive the preventive services such as influenza vaccination and bone densitometry than cancer free controls. Still, these results should be interpreted in the context of suboptimal utilization of preventive services in general, and for cancer survivors in specific. Future research should evaluate the underlying mechanisms and whether utilization of preventive services is associated with overall survival in cancer survivors.
Early and Remote Results of Surgical Treatment of Inferior Vena Cava Thrombosis
Authors: Popovych Yaroslav
Published: April 2018

The objective of the research was to estimate the early and remote results of surgical treatment in patients with deep vein thrombosis of the inferior vena cava.Material and methods. The results of treating 790 patients with lower limb deep vein thrombosis and thrombosis of the inferior vena cava were analyzed. Depending on treatment, all the patients were divided into the following groups: Group IA consisted of 380 (68.5%) patients with deep vein thrombosis who underwent open complete or partial thrombectomy with or without surgical prevention of pulmonary thromboembolism; Group IB consisted of 50 (9.0%) patients with deep vein thrombosis who received combined treatment with surgical prevention of pulmonary thromboembolism; Group IC consisted of 125 (22.5%) patients with transfascial thrombosis who underwent thrombectomy of the apical thrombotic masses of deep veins followed by radical venectomy; Group II consisted of 235 (29.7%) patients with deep vein thrombosis who received conservative anticoagulant therapy only.For investigation of patients, there were used the following laboratory methods of examination: duplex ultrasound scanning, X-ray phlebography, computer tomography, echocardioscopy and radionuclide phleboscintigraphy.Results. The results of surgical and combined methods of treating deep vein thrombosis in clinical subgroups were evaluated using a three-point scale - good, satisfactory and unsatisfactory. The cumulative analysis of the results of the postoperative period during 3 years of follow-up showed that good and satisfactory results were observed in 89.3% of patients of Group IA, 81.7% of patients of Group IB, 88.4% of patients of Group IC, and 35.3% of patients of Group II. Three years after treatment, the signs of chronic venous insufficiency were found in 51.6% of patients who underwent conservative treatment, 36.4% of patients who received combined treatment, 10.2% of patients who underwent partial thrombectomy, 2.9% of patients who received surgical treatment of transfascial thrombosis; they were absent in patients who underwent radical thrombectomy.Conclusions. In quantitative evaluation of the early and remote results of treating deep vein thrombosis of the inferior vena cava, a significant improvement in the patients’ condition in all parameters was observed in the main group as compared to the control one.
Tereny zagrożone odnowionego „ordo missae”
Authors: Głowa Władysław
Published: April 2018

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W 50. rocznicę wydania encykliki Divino afflante Spiritu
Authors: Chmiel Jerzy
Published: April 2018

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Zasady interpretacji tekstów euchologijnych
Authors: Konecki Krzysztof
Published: April 2018

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Obrzęd pogrzebu wiernego świeckiego w okresie paschalnym w liturgii bizantyjskiej
Authors: Nadolski Bogusław
Published: April 2018

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Odpowiedź Sekretariatu Stanu na list towarzystwa
Authors: Caprio Giuseppe
Published: April 2018

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„Słudzy słowa” (Łk 1, 2)
Authors: Jankowski Augustyn
Published: April 2018

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HUGOLIN LANGKAMMER OFM, Wprowadzenie do ksiąg Nowego Testamentu, Wrocław 1979
Authors: Chmiel Jerzy
Published: April 2018

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KLAUS M. BECKER, GERMAN ROVIRA, Aus den Menschen genomen. Berufung und geistliches Leben des Priesters, St. Augustin 1978
Authors: Dziuba Andrzej F.
Published: April 2018

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FRANZ SCHNIDSR, Die verlorenen Söhne. Strukturanalytische und historisch-kritische Untersuchungen zu Lk 15, Gottingen 1977
Authors: Tum Janusz
Published: April 2018

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Błogosławieństwa w mszale Pawła VI
Authors: Małaczyński Franciszek
Published: April 2018

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Kerygmatyczne wartości encykliki Jana Pawła II „Redemptor hominis”
Authors: Grzybek Stanisław
Published: April 2018

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Wypisy źródłowe do dziejów Wawelu. Z archiwaliów kapitulnych i kurialnych krakowskich 1526–1529, wybrał i opracował B. Przybyszewski, Kraków 1984
Authors: Chmiel Jerzy
Published: April 2018

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Jak rozumieć Pieśń nad Pieśniami?
Authors: Brzegowy Tadeusz
Published: April 2018

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Ruch liturgiczny, reforma i odnowa liturgiczna
Authors: Kopeć Jerzy Józef
Published: April 2018

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Prace Komisji Liturgicznej Episkopatu Polski nad realizacją konstytucji liturgicznej w Polsce w latach 1963–1975
Authors: Sobeczko Helmut
Published: April 2018

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Odnowa liturgii w żeńskich wspólnotach zakonnych
Authors: Zielińska A.
Published: April 2018

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Paschalny charakter chrześcijańskiej śmierci
Authors: Hanich Andrzej
Published: April 2018

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Cechy interwencji kapłana w liturgii mszy św.
Authors: Koperek Stefan
Published: April 2018

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O. HUGOLIN LANGKAMMER OFM, Etyka Nowego Testamentu. „Jeśli chcesz wejść do królestwa Bożego”, Wrocław 1985
Authors: Czerski Janusz
Published: April 2018

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SCOTT HAHN, The Lamb's Supper. The Mass as Heaven on Earth. Doubleday, New York-London-Toronto-Sydney-Aucland 1999
Authors: Dziuba Andrzej F.
Published: April 2018

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Czym są błogosławieństwa ewangeliczne?
Authors: Wichrowicz Cyprian Jan
Published: April 2018

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Modlitwa „Alenu”
Authors: Mendecki Norbert
Published: April 2018

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Przepowiadanie nadziei dzisiaj
Authors: Chmiel Jerzy
Published: April 2018

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JAN ŚWIECZYŃSKI, Wskrzesiciele faraonów i pogromcy sztuki, Warszawa 1992
Authors: Fular Marian
Published: April 2018

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Czy i jak rozumiał Jezus cel swojej własnej śmierci?
Authors: Romaniuk Kazimierz
Published: April 2018

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Modlitwy króla judzkiego Ezechiasza (2 Krl 19, 15–19; Iz 38, 3. 9–20)
Authors: Łach Józef
Published: April 2018

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Postawy i gesty celebransa w eucharystycznym zgromadzeniu liturgicznym
Authors: Rojewski Andrzej
Published: April 2018

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SOBÓR DROGOWSKAZEM. Rozważania dla kapłanów i kleryków, Kalwaria Zebrzydowska 1989
Authors: Grzybek Stanisław
Published: April 2018

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Dotknięcie trędowatego (Mk 1, 40–45)
Authors: Wojciechowski Michał
Published: April 2018

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Kongres Wykładowców Liturgiki w Holandii (1988)
Authors: Boguniowski Józef Wacław
Published: April 2018

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Dlaczego Kościół poświęcił Matce Boskiej dzień sobotni
Authors: Sitkowski Tadeusz
Published: April 2018

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Śp. Matka Innocenta, przełożona Domu Polskiego w Jerozolimie
Authors: D. Ks.
Published: April 2018

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De profundis. Rozważanie Ernesta Hello
Authors: Hello Ernest
Published: April 2018

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Indywidualne czytanie Pisma Świętego
Authors: Smereka Władysław
Published: April 2018

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Krzak gorejący
Authors: Sczaniecki Paweł
Published: April 2018

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Polskie przekłady mszału rzymskiego
Authors: Sitarz Eugeniusz
Published: April 2018

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Uwagi do Psalmu 68
Authors: Zolli Eugeniusz
Published: April 2018

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Wykopaliska z Mari a Stary Testament
Authors: Wodecki Bernard
Published: April 2018

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Wigilia wielkanocna w diecezji katowickiej
Authors: Rak Romuald
Published: April 2018

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Namaszczenie w Betanii
Authors: Lipiński Edward
Published: April 2018

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Pieśń o stworzeniu (Rodz. 1, 1–2, 4)
Authors: Klawek Aleksy
Published: April 2018

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Dubia circa interpretationem instructionis de musica sacra
Authors: Rituum Congregatio Sacra
Published: April 2018

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„Wzór macie w nas” (Flp 3, 17). Kształtująca się osobowość apostoła Pawła w świetle jego Listu do Filipian
Authors: Jankowski Augustyn
Published: April 2018

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Rodzaj literacki Księgi Tobiasza
Authors: Grzybek Stanisław
Published: April 2018

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Pismo św. w liturgii
Authors: Świerzawski Wacław
Published: April 2018

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Pobożność Kościoła
Authors: Szamota Stanisław
Published: April 2018

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Św. Paweł przybywa do Europy
Authors: Klawek Aleksy
Published: April 2018

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Linie rozwojowe teologii polskiej
Authors: Przybylski Bernard
Published: April 2018

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Sprawozdanie z działalności Polskiego Towarzystwa Teologicznego w Krakowie za rok akademicki 1965/1966
Authors: Kowalski Jan
Published: April 2018

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W stronę ekumenicznego czynu (na marginesie ogłoszonego przez Sekretariat do Spraw Jedności Dyrektorium Ekumenicznego)
Authors: Skowronek Alfons
Published: April 2018

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Funkcja wychowawcza liturgii
Authors: Małaczyński Franciszek
Published: April 2018

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Problemy współczesnej hermeneutyki biblijnej
Authors: Chmiel Jerzy
Published: April 2018

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Liturgia a duchowość chrześcijańska (według konstytucji II Soboru Watykańskiego o liturgii)
Authors: Słomka Walerian
Published: April 2018

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Sakramenty – prasytuacje chrześcijanina
Authors: Maliński Mieczysław
Published: April 2018

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Konstytucja apostolska o sakramencie bierzmowania
Authors: VI Paweł
Published: April 2018

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Kult św. Stanisława biskupa w Czechach
Authors: Rynes Vaclav
Published: April 2018

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Przemówienie ks. biskupa Wincentego Urbana z okazji otwarcia XII Kongresu Biblistów Polskich we Wrocławiu
Authors: Urban Wincenty
Published: April 2018

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Resurrexit. Actes du Symposium International sur la Résurrection de Jésus (Romae 1970), éd. E. Dhanis SJ, Libreria Editrice Vaticana 1974
Authors: Chmiel Jerzy
Published: April 2018

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Inšpirácia Svätého písma. Komentár k 3. kapitole Dei Verbum
Authors: Tyrol Anton
Published: April 2018

Konstytucja dogmatyczna Dei Verbum jest doskonałą pomocą do ożywienia duchowości współczesnego człowieka, ponieważ w najwłaściwszy sposób ukazuje problemy wiary w wymiarze personalnym: Objawienie Boże, Tradycję i Boskie natchnienie. Ich zrozumienie teologiczne przeniosła na Stary i Nowy Testament, a rozdział VI konstytucji przedstawia praktyczne uwagi dla życia wierzących. Rozdział o Boskim natchnieniu ułatwia nam głębsze przeżywanie Bożej obecności w codziennym korzystaniu z Pisma Świętego. W ten sposób pomaga nam lepiej zrozumieć wielkość daru, jakim jest dla nas Pismo Święte.
O Świętej Jadwidze Królowej mówią
Authors: Jagosz Michał
Published: April 2018

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Biblijna medytacja o Duchu Świętym
Authors: Żychlińska Bernadetta
Published: April 2018

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Organy w liturgii Kościoła
Authors: Sinka Tarsycjusz
Published: April 2018

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JAN OGRODZKI, Słowo i kontemplacja. Biblijne kamienie milowe na drodze wiary i życia duchowego, Michalineum 1997
Authors: Chmiel Jerzy
Published: April 2018

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Eucharystia w Bożym planie zbawienia (I)
Authors: Bartnicki Roman
Published: April 2018

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50. zjazd Studiorum Novi Testamenti Societatis (Praga 1995)
Authors: Chmiel Jerzy
Published: April 2018

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Starożytne dzieje i kultura. Badacze i badania w Polsce, opracowanie i redakcja Tadeusz Kotula, Andrzej Ładomirski, Wiesław Suder, Wydawnictwo Uniwersytetu Wrocławskiego, Wrocław 1995
Authors: Śliwa Joachim
Published: April 2018

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Śp. ks. prof. Theodor Schnitzler
Authors: Jagielski Mirosław
Published: April 2018

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Family Consultation to Reduce Early Hospital Readmissions among Patients with End Stage Kidney Disease
Authors: Jasinski Matthew J. , Lumley Mark A. , Soman Sandeep , Yee Jerry , Ketterer Mark W.
Published: April 2018

Background and objectives

The US Centers for Medicare and Medicaid Services have mandated reducing early (30-day) hospital readmissions to improve patient care and reduce costs. Patients with ESKD have elevated early readmission rates, due in part to complex medical regimens but also cognitive impairment, literacy difficulties, low social support, and mood problems. We developed a brief family consultation intervention to address these risk factors and tested whether it would reduce early readmissions.

Design, setting, participants, & measurements

One hundred twenty hospitalized adults with ESKD (mean age=58 years; 50% men; 86% black, 14% white) were recruited from an urban, inpatient nephrology unit. Patients were randomized to the family consultation (n=60) or treatment-as-usual control (n=60) condition. Family consultations, conducted before discharge at bedside or via telephone, educated the family about the patient’s cognitive and behavioral risk factors for readmission, particularly cognitive impairment, and how to compensate for them. Blinded medical record reviews were conducted 30 days later to determine readmission status (primary outcome) and any hospital return visit (readmission, emergency department, or observation; secondary outcome). Logistic regressions tested the effects of the consultation versus control on these outcomes.

Results

Primary analyses were intent-to-treat. The risk of a 30-day readmission after family consultation (n=12, 20%) was 0.54 compared with treatment-as-usual controls (n=19, 32%), although this effect was not statistically significant (odds ratio, 0.54; 95% confidence interval, 0.23 to 1.24; P=0.15). A similar magnitude, nonsignificant result was observed for any 30-day hospital return visit: family consultation (n=19, 32%) versus controls (n=28, 47%; odds ratio, 0.53; 95% confidence interval, 0.25 to 1.1; P=0.09). Per protocol analyses (excluding three patients who did not receive the assigned consultation) revealed similar results.

Conclusions

A brief consultation with family members about the patient’s cognitive and psychosocial risk factors had no significant effect on 30-day hospital readmission in patients with ESKD.
Credit Risk Stress Testing of Commercial Banks in Tunisia
Authors: Youssef Amel Ben
Published: April 2018

Stress tests of credit risk is greatly affected by data constraints in Tunisian banking system. Aiming to improve the assessment of credit risk in such conditions, we propose a model to conduct a macro stress test of credit risk for a sample of ten Tunisian commercial banks based on scenario analysis.

The approach consists first in explaining the credit risk for each bank in terms of macroeconomic and bank-specific variables through a static fixed effects model, second in a stress-testing exercise using the Monte Carlo Simulation for generating credit risk losses distributions in case of different scenarios and for determining unexpected losses for each bank.

The panel analysis applied suggests a robust negative relationship between the credit risk of bank loans and real GDP growth, with a lag response of four periods. In addition, return on assets ratio and bank size show significant negative effect on credit quality, while the net loans to total asset ratio is positively associated with it.

The credit risk stress testing results indicate that an adverse scenario of economic downturn produces increase of the frequency of the higher credit loss comparatively to the lower ones for all banks of the sample and that the estimated unexpected losses that would take place in a stress situation can be covered by available capital of these banks.
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING SIMULTANEOUS UVSPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF EMTRICITABINE, TENOFOVIR DISOPROXIL FUMARATE, COBICISTAT, AND ELVITEGRAVIR IN PURE AND PHARMACEUTICAL DOSAGE FORM
Authors: U Harini , Akm Pawar
Published: April 2018

Objective: The objective of this research work was to develop and validate a simple, precise, and accurate new ultraviolet-spectrophotometric method for the simultaneous estimation of emtricitabine (EMT), tenofovir disoproxil fumarate (TDF), cobicistat (COB), and elvitegravir (ELV) in pure and pharmaceutical marketed dosage form (stribild).Methods: Simultaneous equation method (Vierordt’s method) was developed for simultaneous determination of several mixtures containing two or more absorbing drugs (p, q, r, and s) each of which absorbs at the λ max of the other. Forced degradation studies were also conducted, and the drugs were subjected to various stress conditions such as acid hydrolysis, base hydrolysis, oxidative, photolytic, and thermal degradation.Results: The λ max of EMT, ten TDF, COB, and ELV are 283 nm, 259 nm, 240 nm, and 258 nm, respectively. The linearity ranges for the four drugs are EMT (4–24 μg/ml), TDF (10–50 μg/ml), COB (10–120 μg/ml), and ELV (2–10 μg/ml).Conclusion: The Vierordt’s method was successfully applied for simultaneous determination of EMT, TDF, COB, and ELV in a mixture of sample solution (pharmaceutical dosage form) and the results obtained were validated and found to be accurate, precise, linear, rugged, and robust.
A COMPREHENSIVE INFORMATIVE NOTE ON ASCITES
Authors: Singh Navneet , Patyar Sazal , Chandra Talniya Naveen
Published: April 2018

Ascites impairs both the physical and mental dimensions of quality of life in patients. The patients due to unawareness do not report to medical practitioners in the early stage of disease, and also in few cases, medical practitioners due to lack of adequate expertise face difficulty to ensure the early stage detection for causes of ascites, i.e., due to cirrhosis, cancer, congestive heart failure, mycobacterium tuberculosis, or others. Ascites is a symptom of progression of single disease or multiple diseases. Gross collection of fluid in peritoneal cavity may initiate a series of problems such as spontaneous bacterial peritonitis and an increase in abdominal distension and discomfort and hinder the mobility of the patient and dullness and loss of appetite. In the present review, a detail study over the ecology of ascites has been done with emphasizing on diagnosis by history and physical examination, clinical examination, and imagining techniques followed by management of treatment through general guidelines, and various available therapies are covered.
A REVIEW ON ENDOTHELINS: AN UPDATE
Authors: Nandagopal Anitha , Shamsia Mubeen Unnisa
Published: April 2018

Endothelin (ET) is the most potent vasoconstrictor. It is secreted by the endothelial cells. At low concentration, it acts as an agonist for endothelium-derived relaxing factors and thereby causes vasodilatation, and at higher concentration it acts as a potent vasoconstrictor. It is synthesized by proteolytic cleavage of preproendothelin to proendothelin by the action of metallopeptidases and chymase, which is further cleaved into mature form of ET by endothelin converting enzyme. There are four isoforms of ET, namely, ET-1, ET-2, ET-3, and ET-4. ET acts on 2 types of receptors. Binding of ET-1 to ETA receptor at the vascular smooth muscle cells induces vasoconstriction. It also produces vasoconstriction by acting on the ETB2 receptor of vascular smooth muscle cells but promotes vasodilatation at ETB1 receptor present on the endothelial cell.
REVIEW OF THE CURRENT STATUS OF STUDY OXYTROPIS
Authors: A Sh Amirkhanova , G O Ustenova
Published: April 2018

The use of plants for medical purposes has been known since ancient times, and despite progress in the synthesis of medicinal products, herbal remedies continue to occupy a significant place in modern medicine. As promising sources of biologically active substances of natural origin, attention is attracted by representatives of the domestic flora from the family Fabaceae. The article gives an analysis of the current state of the study of the genus of Oxytropis and shows the prospects for their comprehensive study. Work in the herbarium fund of the Institute with a collection of species of Oxytropis glabra Lam. DC. allowed to identify the presence of at least 10 herbarium sheets. While analyzing the internet sources, we collected materials on the genus and species of Oxytropis which have been investigated for many years. When analyzing internet resources, it was established that the widely used traditional Tibetan, Chinese, Mongolian, and Buryat medicine should include representatives of the genus Oxytropis (DC.) of the family Fabaceae (L.).We have studied the species of the Oxytropis and compiled a table on their chemical composition and pharmacological action.
CYTOTOXIC EFFECT OF SYNTHESIZED SILVER NANOPARTICLES BY PULSE LASER ABLATION ON BREAST CANCER CELL LINE (AMJ13) FROM IRAQI PATIENT AND NORMAL HUMAN LYMPHOCYTES
Authors: N R Alrawi Nawfal , Q Al-ani Mohammed , Yaseen Nahi Y
Published: April 2018

Objective: Synthesized silver nanoparticles (AgNPs) in liquids were investigated as anticancer cells in the present study. Cytotoxic activities of six different concentrations 0.78, 1.56, 3.125, 6.25, 12.5, and 25 μg/ml of AgNPs against human breast cancer cell line (AMJ13) and lymphocytes were assessed with MTT assay.Methods: A Q-Switched Nd: YAG pulsed laser (λ=1064 nm, 800 mJ/pulse) was used for ablation of a pure silver plate to synthesis AgNPs in the polyvinylpyrrolidone and deionize distilled water. Ultraviolet-visible spectroscopy confirmed the synthesis of AgNPs and zeta potential was evaluated. Morphology and size were analyzed by transmission electron microscope. AgNPs concentrations were determined by atomic absorption spectroscopy. Possibilities of apoptosis induction were confirmed using mitochondrial membrane potential assay, DNA fragmentation assay, and glutathione (GSH) assay.Results: The results indicated that AgNPs were able to induce an inhibition of AMJ13 cells compared their damaging effect toward normal lymphocytes were at minimal according to viability with MTT assay.. Furthermore, these results suggested that AgNPs-induced mitochondrial-mediated apoptosis cause DNA fragmentation, but no significant change in GSH level in AMJ13 cells.Conclusions: The overall results indicated that the physically synthesized AgNPs were exhibited dose-dependent cell death in AMJ13 breast cancer cell line, while the effect of AgNPs on lymphocytes was very low, suggesting that physically synthesized AgNPs might be a potential alternative agent for human breast cancer therapy.