bluuebunny/crossref_metadata_2025 huggingface dataset:
Review of Regional Workplace Development Cases
Authors: Reiman Arto , Väyrynen Seppo
Published: October 2011

The labour-intensive manufacturing industry faces many working-life challenges in the rural, sparsely populated northern areas of Finland at both operational and strategic levels. These challenges vary, being in interaction with both technical and social systems and their combinations. In this paper, the authors review and evaluate needs, actions and results carried out to improve work and productivity in three regional industrial development cases. The actions discussed in this paper, such as work environment management, change management in general and the sociotechnical approach, are essential for the success of enterprises. Using the results of this research as a basis for developing design knowledge, two guidelines for strategic management purposes are proposed. These guidelines implement sociotechnical aspects into the work environment and its management, and recognise that it is important to focus on human and organisational factors in addition to technical end environmental aspects. A proposal for a specific, unique self-assessment tool for evaluating the level of the quality of the work environment in SMEs is also suggested.
Ontology Mapping Validation
Authors: Serpeloni Felipe , Moraes Regina , Bonacin Rodrigo
Published: October 2011

The use of ontologies and ontology mappings is increasing in companies. Often the same context is modeled in different ontologies. Mapping is necessary to integrate these ontologies; however, in many cases these mappings are incorrect, i.e., they incorrectly link semantic concepts with different meanings. Tools that validate these mappings are necessary to ensure reliable communication between heterogeneous systems. This validation cannot be done in a completely automatic way, because the mappings are based on human interpretation. This work describes a semi-automatic tool that supports this activity, based on graphs that generate instances validated in a semi-automatic process that aims to ensure mapping robustness. This algorithm deals with an NP-Complete problem in order to generate all the instances. This paper presents a first prototype of the tool and the methodology used to validate the instances automatically generated by the tool.
The Backseat Control Architecture for Autonomous Robotic Vehicles: A Case Study with the Iver2 AUV
Authors: Eickstedt Donald P. , Sideleau Scott R.
Published: October 2011

Abstract In this paper, an innovative hybrid control architecture for real-time control of autonomous robotic vehicles is described as well as its implementation on a commercially available autonomous underwater vehicle (AUV). This architecture has two major components, a
behavior-based intelligent autonomous controller and an interface to a classical dynamic controller that is responsible for real-time dynamic control of the vehicle given the decisions of the intelligent controller over the decision state space (e.g., vehicle course, speed, and depth). The
driving force behind the development of this architecture was a desire to make autonomy software development for underwater vehicles independent from the dynamic control specifics of any given vehicle. The resulting software portability allows significant code reuse and frees autonomy software
developers from being tied to a particular vehicle manufacturer’s autonomy software and support as long as the vehicle supports the required interface between the intelligent controller and the dynamic controller. This paper will describe in detail the components of the backseat driver
architecture as implemented on the Iver2 underwater vehicle, provide several examples of its use, and discuss the future direction of the architecture.
Voyager: An Interactive Software for Visualizing Large, Geospatial Data Sets
Authors: Anderson John C. , Andres Jose M. , Davis McKay , Fujiwara Kayo , Fang Tie , Nedbal Michael
Published: October 2011

AbstractThis paper describes the development and main operational capabilities of Voyager, a PC-based, geospatially-enabled piece of software that can fuse and visualize large, multi-variable data sets that change in space (XYZ) and time (T). The new software has the ability
to simultaneously visualize imagery, bathymetry/terrain, true volumetric (voxel), and flow field data in a fully interactive geo-referenced mode. In addition to providing global coverage, a key feature of this software is the capability to interactively visualize large data sets while operating
on a desktop PC. This is achieved by using tiling and level-of-detail (LOD) technology for terrain, imagery, and volumetric data, as well as compression techniques and the multi-threading capabilities of modern PCs.
BathyBoat: An Autonomous Surface Vessel for Stand-alone Survey and Underwater Vehicle Network Supervision
Authors: Brown Hunter C. , Jenkins Liza K. , Meadows Guy A. , Shuchman Robert A.
Published: October 2011

AbstractExploration of remote environments, once the domain of intrepid adventurers, can now be conducted in relative safety using unmanned vehicles. This article describes the joint University of Michigan (UMich) and Michigan Tech Research Institute’s project to design
and to build a new autonomous surface vessel (ASV) for use in research, education, and resource management as well as in the commercial sector.Originally designed to assist with bathymetric surveys in the wilderness of northern Alaska, the BathyBoat has become a test-bed platform
for new research in collaborative heterogeneous underwater robotic search and survey missions in ports, harbors, lakes, and rivers. The UMich Marine Hydrodynamics Laboratories are actively researching autonomous technologies such as cooperative navigation, surface vessel control, and multivehicle
search and survey using the BathyBoat and the UMich Perceptual Robotics Laboratory’s Iver2 autonomous underwater vehicles.This article presents an overview of these research topics and highlights relevant real-world testing and recent missions involving the BathyBoat
ASV on Alaska’s North Slope, the harbors of Illinois, and various riverine environments in Michigan.
AquaOptical: A Lightweight Device for High-rate Long-range Underwater Point-to-Point Communication
Authors: Doniec Marek , Detweiler Carrick , Vasilescu Iuliu , Chitre Mandar , Hoffmann-Kuhnt Matthias , Rus Daniela
Published: October 2011

AbstractThis article describes AquaOptical, an underwater optical communication system. Three optical modems have been developed: a long-range system, a short-range system, and a hybrid system. We describe their hardware and software architectures and highlight trade-offs.
We present pool and ocean experiments with each system. In clear water, AquaOptical achieved a data rate of 1.2 Mbit/s at distances up to 30 m. In water with visibility estimated at 3 m, AquaOptical achieved communication at data rates of 0.6 Mbit/s at distances up to 9 m.
Working in Freshwater: The Great Lakes Observing System Contributions to Regional and National Observations, Data Infrastructure, and Decision Support
Authors: Read Jennifer , Klump Val , Johengen Tom , Schwab David , Paige Kelli , Eddy Stuart , Anderson Eric , Manninen Christine
Published: October 2011

AbstractThe Laurentian Great Lakes is the world’s largest freshwater ecosystem. A charge of the Great Lakes Observing System (GLOS) Regional Association is to help coordinate and integrate data and information relative to the needs of multiple user communities—decision
makers with responsibility for coastal resources, maritime operations, human health and water security data, and issues associated with adapting to climate change and weather-related hazards. This article outlines the process GLOS has developed for determining regional data and information
needs, how GLOS outreach activities inform data management functions and the development of decision support tools, and how the nearshore network of multiple observation platform types was conceived and is being implemented. The article finishes with a case study of this approach as it is
being applied to source water protection, spill response, and search and rescue in the St. Clair River, Lake St. Clair, and Detroit River, the connecting channels that link Lake Huron to Lake Erie.
Integrated Ocean Observing System in Support of Forecasting Harmful Algal Blooms
Authors: Jochens Ann E. , Malone Thomas C. , Stumpf Richard P. , Hickey Barbara M. , Carter Melissa , Morrison Ru , Dyble Juli , Jones Burt , Trainer Vera L.
Published: October 2011

AbstractHarmful algal bloom (HAB) events threaten human health, living marine resources, and ecosystem health. Their occurrence has increased in frequency, duration, and severity over the last several decades. Preventing, controlling, or mitigating the impacts of HABs requires
the development of permanent, operational ocean observing systems that continuously provide the data and information necessary for rapid detection and timely forecasts of changes in ecosystem states. Key elements of such observing systems are observations and modeling that must be efficiently
linked via data management and communication networks. Building the observing system begins by integrating existing assets, is followed by incorporation of new technologies and knowledge, and is guided by the data and information needs of decision makers. User needs are particularly important
for development of operational forecast models and new sensors for measuring required biological (e.g., HAB species abundance) and chemical (e.g., concentrations of HAB toxins) variables in near real time. This article describes operational observing system requirements for a HAB forecasting
system and current efforts by Regional Associations to develop these observing systems for targeted species in their respective regions.
IOOS® Contributions to the Decision-Making Process for Mariners and Coastal Managers
Authors: Thomas Julie , Boicourt William , Kerkering Heather , Leonard Lynn , Ostrander Chris , Watts Irene
Published: October 2011

AbstractIn 2009, the National Operational Wave Observation Plan, prepared for the U.S. Integrated Ocean Observing System (IOOS®) and led by the National Data Buoy Center and the United States Army Corps of Engineers (USACE), outlined a comprehensive
plan that will serve as a basis for a nationwide, high-quality surface-wave monitoring network. One of the projects that the USACE and the California Department of Boating and Waterways cooperatively funds is the Coastal Data Information Program (CDIP). The CDIP is based at the Scripps Institution
of Oceanography with its main focus on high-resolution directional wave measurements. The CDIP serves as one of the USACE’s contributions toward IOOS, thus promoting sustained and quality wave measurements throughout the United States.This article describes examples of how reliable,
accurate wave data serve the maritime community and coastal managers. Several of the CDIP buoys are moored at the entrances to ports and harbors or close to the nearshore where waves impact the coastal zone. As evident, each port or harbor has unique conditions and therefore its own set of
challenges. Specific examples are demonstrated as to how CDIP and IOOS have played a key role in the decision-making process, by contributing to the safety or economics of marine operations and coastal management. The real-time data are available on the Southern California Coastal Observing
System (http://sccoos.org) and the corresponding Regional Association’s Websites. The data are also transmitted hourly to the National Oceanic and Atmospheric Administration’s National Data Buoy Center and the National Weather
Service.
Use of the EventViewer for Visualizing and Exploring Events Extracted From Ocean Observing System Data
Authors: Beard Kate , Emerson Jake , Deese Heather E. , Rude Avinash , Scott Mike , Pettigrew Neal R.
Published: October 2011

AbstractRapidly expanding data collections from ocean observing systems create a need for new tools to process, to explore, and to analyze data. This article presents capabilities of the EventViewer in the context of exploring ocean observing system data. The EventViewer
is a graphical user interface for visualizing and exploring patterns in events where events constitute changes of interest in a time series. The EventViewer allows users to make queries on events stored in an events database and explore various spatial, temporal, and thematic patterns in events.
Once events are selected, the user can assign event spatial, temporal, and thematic categories to graphic display elements in the interface called bands, stacks, and panels. Selected events are displayed according to their associations with the user-specified categories. The spatial, temporal,
and thematic categories can be directly manipulated and rearranged among the bands, stacks, and panels to change the view of events and highlight different patterns. The EventViewer supports exploration of periodic patterns, spatial and temporal trends, and event‐event relationships.
The EventViewer functionality is illustrated with oceanographic events extracted from ocean observing system sensor data collected in the Gulf of Maine. Events were extracted from multiple time series variables collected at a number of locations and depths.
United States Integrated Ocean Observing System and the Shellfish Growers Partnership
Authors: Gouldman Carl , Wiegardt Mark , Cudd Sue , Geubtner Jessica
Published: October 2011

AbstractThis scientific note provides a summary of a new partnership developing between two groups who have found a common area of interest focused on the value of building a better network for real-time coastal ocean observing data and information and how such a network
may inform research on ocean acidification. The note examines the development of the partnership over the past year, which is providing mutually beneficial opportunities for interaction. Shellfish growers are able to learn about a federal and regional framework providing integrated data along
our coasts, and the Integrated Ocean Observing System program is able to learn directly from one of its stakeholders who demonstrates the clear economic and scientific value of coastal, ocean, and Great Lakes observing systems. By working together, the two are finding ways to improve our coastal
observing networks and to support research on ocean acidification.
Antimicrobial Activity of Copper Alone and in Combination with Lactic Acid againstEscherichia coliO157:H7 in Laboratory Medium and on the Surface of Lettuce and Tomatoes
Authors: Gyawali Rabin , Ibrahim Salam A. , Abu Hasfa Salma H. , Smqadri Shahnaz Q. , Haik Yosef
Published: October 2011

The objective of this study was to evaluate the effect of copper alone and in combination with lactic acid againstE. coliO157:H7 in laboratory medium and on the surface of lettuce and tomatoes. Four strains ofE. coliO157:H7 were individually inoculated into BHI broth containing different concentrations of copper (5, 10, 20, and 40 ppm, w/v), lactic acid (0.1 and 0.2%, v/v), and their combinations. After incubation, aliquots of 1 mL from each sample were withdrawn and plated on BHI agar to determine the bacterial population. Significant growth inhibition (P<0.05) was observed with a combination treatment of copper (40 ppm) and lactic acid (0.2%). The population ofE. coliO157:H7 was reduced by 3.93 and 3.39 log on the surface of lettuce and tomato samples, respectively, when treated with the same combination. This indicates that combination of copper and lactic acid could be used as an effective solution to inhibitE. coliO157:H7 on fresh produce.
Anopheles plumbeus Stephens, 1828: a neglected malaria vector in Europe
Authors: Bueno-Marí Rubén , Jiménez-Peydró Ricardo
Published: October 2011

Traditionally field and laboratory research about malaria vectors in Europe have been mainly focused on the species of the Anopheles maculipennis complex. However, although malaria is essentially a rural disease, potential urban vectors merit attention. Because only a few European Anopheles species can breed in urban environments, improving knowledge about their bioecology is necessary to implement effective control measures. Among these opportunistic species, Anopheles plumbeus has a distinctive dendrolimnic behavior, being able to complete its larval development in small containers. The aim of this paper is to provide a thorough review of the limited studies on An. plumbeus with the aim of providing useful epidemiological information.
Artinian and Non-Artinian Local Cohomology Modules
Authors: Dibaei Mohammad T. , Vahidi Alireza
Published: October 2011

Let M be a finite module over a commutative noetherian ring R. For ideals a and b of R, the relations between cohomological dimensions of M with respect to a, b, a ⋂ b and a + b are studied. When R is local, it is shown that M is generalized Cohen–Macaulay if there exists an ideal a such that all local cohomology modules of M with respect to a have finite lengths. Also, when r is an integer such that 0 ≤ r < dimR(M), any maximal element q of the non-empty set of ideals ﹛a : (M) is not artinian for some i, i ≥ r} is a prime ideal, and all Bass numbers of (M) are finite for all i ≥ r.
Literate serialization of linguistic metamodels
Authors: Bański Piotr
Published: October 2011

As part of an effort to bring ISO modeling closer to TEI markup in the sphere of dictionary encoding, the author combines the practice of visual modelling language resources that is by now standard in ISO TC37 SC4 (especially in the ISO Lexical Markup Framework), with a reasonably common, but somewhat model-less practice of encoding dictionaries by means of the tagset offered by Chapter 9 of the TEI Guidelines.
The False Security of Closed XML Systems
Authors: Beck Jeff
Published: October 2011

Creating and using XML documents in a closes system gives a false sense of “All’s Well”. A Closed XML system is one where a single party creates and uses the XML documents. Certainly this happens all of the time. We all create little XML documents with one-off throw-away models for one task or another that only we use. These documents will not be the focus here. When documents are created in a closed XML workflow and sent to another entity - such as an archive - for reuse, publishers can quickly learn that the content they have been accumulating is not useful for anything outside of their system and may not be useful if their own systems are upgraded or changed.

The checks and procedures that must be put in place to support XML interchange between entities should be applied within closed XML systems to keep the content usable and useful.
A pragmatic approach to XML interoperability – the Component Metadata Infrastructure (CMDI)
Authors: Broeder Daan , Schonefeld Oliver , Trippel Thorsten , Van Uytvanck Dieter , Witt Andreas
Published: October 2011

XML has been designed for creating structured documents, but the information that is encoded in these structures are, by definition, out of scope for XML. Additional sources, normally not easily interpretable by computers, such as documentation are needed to determine the intention of specific tags in a tag-set. The Component Metadata Infrastructure (CMDI) takes a rather pragmatic approach to foster interoperability between XML instances in the domain of metadata descriptions for language resources. This paper gives an overview of this approach.
When XQuery and SparQL Collide
Authors: Cagle Kurt
Published: October 2011

Far from being competing technologies, XQuery and SparQL are potential collaborators in data extraction and manipulation. Since an XML database can also function as a triple store, it’s possible to combine the languages so that each executes what it’s optimized for while avoiding process boundary serialization problems and also generate output like XHTML from queries across a variety of document types.
One Href is not Enough
Authors: van der Vlist Eric
Published: October 2011

The web is hyperlinks for the masses.

Hyperlinks are an old concept that has been invented before the web and to achieve this remarkable success, the web had to come out with a very simplified version of hyperlinks.

In the process a lot of features have been lost and some of them, such as the possibility to link to multiple targets have been lost.

This talk proposes to use modern techniques to regain this ability while remaining conform to existing standards and running in existing browsers.
Error characterization of CO2 vertical mixing in the atmospheric transport model WRF-VPRM
Authors: Kretschmer R. , Gerbig C. , Karstens U. , Koch F.-T.
Published: October 2011

Abstract. One of the dominant uncertainties in inverse estimates of regional CO2 surface-atmosphere fluxes is related to model errors in vertical transport within the planetary boundary layer (PBL). In this study we present the results from a synthetic experiment using the atmospheric model WRF-VPRM to realistically simulate transport of CO2 for large parts of the European continent at 10 km spatial resolution. To elucidate the impact of vertical mixing error on modeled CO2 mixing ratios we simulated a month during the growing season (August 2006) with different commonly used parameterizations of the PBL (Mellor-Yamada-Janjic (MYJ) and Yonsei-University (YSU) scheme). To isolate the effect of transport errors we prescribed the same CO2 surface fluxes for both simulations. Differences in simulated CO2 mixing ratios (model bias) were on the order of 3 ppm during daytime with larger values during night. We present a simple method to reduce this bias by 70–80% when the true height of the mixed layer is known.
From precipitation to groundwater baseflow in a native prairie ecosystem: a regional study of the Konza LTER in the Flint Hills of Kansas, USA
Authors: Steward D. R. , Yang X. , Lauwo S. Y. , Staggenborg S. A. , Macpherson G. L. , Welch S. M.
Published: October 2011

Abstract. Methods are developed to study hydrologic interactions across the surficial/groundwater interface in a native prairie ecosystem. Surficial ecohydrologic processes are simulated with the USDA's EPIC model using daily climate data from the Kansas Weather Data Library, vegetation and soil data from the USDA, and current land-use management practices. Results show that mean annual precipitation (from 1985–2005) is partitioned into 13% runoff regionally and 14% locally over the Konza LTER, lateral flow through soil is 1% regionally and 2% locally, groundwater recharge is 11% regionally and 9% locally, and evapotranspiration accounts for the remaining 75%. The spatial distribution of recharge was used in a regional Modflow groundwater model that was calibrated to existing groundwater observations and field measurements gathered for this study, giving a hydraulic conductivity in the Flint Hills region of 1–2 m day−1 with a local zone (identified here) of 0.05–0.1 m day−1. The resistance was set to fixed representative values during model calibration of hydraulic conductivity, and simple log-log relations correlate the enhanced recharge beneath ephemeral upland streams and baseflow in perennial lowland streams to the unknown resistance of the streambeds. Enhanced recharge due to stream transmission loss (the difference between terrestrial runoff and streamflow) represents a small fraction of streamflow in the ephemeral upland and the resistance of this streambed is 100 000 day. Long-term baseflow in the local Kings Creek watershed (2% of the groundwater recharge over the watershed) is met when the resistance of the lowland streambed is 1000 day. The coupled framework developed here to study surficial ecohydrological processes using EPIC and groundwater hydrogeological processes using Modflow provides a baseline hydrologic assessment and a computational platform for future investigations to examine the impacts of climate change, vegetative cover, soils, and management practices on hydrologic forcings.
The evolution of electron current sheet and formation of secondary islands in guide field reconnection
Authors: Huang C. , Lu Q. , Yang Z. , Wu M. , Dong Q. , Wang S.
Published: October 2011

Abstract. Two-dimensional (2-D) particle-in-cell (PIC) simulations are performed to investigate the evolution of the electron current sheet (ECS) in guide field reconnection. The ECS is formed by electrons accelerated by the inductive electric field in the vicinity of the X line, which is then extended along the x direction due to the imbalance between the electric field force and Ampere force. The tearing instability is unstable when the ECS becomes sufficiently long and thin, and several seed islands are formed in the ECS. These tiny islands may coalesce and form a larger secondary island in the center of the diffusion region.
On the Asymptotic Behavior of p-Faber Polynomials for Domains with Piecewise Analytic Boundary
Authors: Tunc T. , Kucukaslan M.
Published: October 2011

Let be a domain bounded by a piecewise analytic Jordan's curve L, and let denote the p-Faber polynomials associated with G. We
derive estimates of the form , for , where
depends on geometric properties of L and the parameter p. Also, we show that O cannot be replaced by o in the relation given above.
CC Bond Formation via CH Activation and CN Bond Formation via Oxidative Amination Catalyzed by Palladium‐ Polyoxometalate Nanomaterials Using Dioxygen as the Terminal Oxidant
Authors: Chng Leng Leng , Zhang Jie , Yang Jinhua , Amoura Makhlouf , Ying Jackie Y.
Published: October 2011

An efficient heterogeneous palladium‐polyoxometalate catalyst with the formula Pd‐H6PV3Mo9O40/C has been successfully developed for carbon‐carbon (CC) bond formation via carbon‐hydrogen (CH) activation and carbon‐nitrogen (CN) bond formation via oxidative amination using oxygen as the terminal oxidant. The coupling processes are simple, and use relatively mild conditions to form the desired products. In addition, less waste is generated as no additional reagents such as organic/inorganic oxidants are required, and water is the only by‐product generated.
Highly (≥98%) Stereo‐ and Regioselective Trisubstituted Alkene Synthesis of Wide Applicability via 1‐Halo‐1‐alkyne Hydro‐ boration–Tandem Negishi–Suzuki Coupling or Organoborate Migratory Insertion
Authors: Xu Shiqing , Lee Ching‐Tien , Rao Honghua , Negishi Ei‐ichi
Published: October 2011

(Z)‐1‐Halo‐1‐alkenylboranes (7), preparable in 80–90% yields as ≥98% isomerically pure compounds via hydroboration of 1‐halo‐1‐alkynes, have been converted to a wide range of trisubstituted alkenes via three different routes in the tail‐to‐head (T‐to‐H) direction, i.e., (i) palladium‐catalyzed Negishi–Suzuki tandem alkenylation, (ii) treatment with organolithium or Grignard reagents to generate α‐bromo‐1‐alkenylboronate complexes that can undergo migratory insertion of a carbon group (R2) to form (E)‐alkenylboranes with inversion of alkene configuration (≥98% inversion), followed by fluoride‐promoted Suzuki alkenylation, and (iii) Negishi coupling to generate (Z)‐alkenylboranes in ≥98% retention of configuration, followed by treatment with organolithium or Grignard reagents to produce trisubstituted alkenes with reversed stereo configurations. The synthetic utility of the present methodology has been demonstrated in the highly selective synthesis of the side chain of scyphostatin in 28% yield over nine steps in the longest linear sequence from allyl alcohol. Thus, this new tandem protocol has been emerged as the most widely applicable and highly selective route to trisubstituted alkenes including those that are otherwise difficult to prepare.
Efficient Trifluoromethylation of Activated and Non‐Activated Alkenyl Halides by Using (Trifluoromethyl)trimethylsilane
Authors: Hafner Andreas , Bräse Stefan
Published: October 2011

An efficient method for the trifluoromethylation of halogenated double bonds by using in situ generated “trifluoromethyl copper” is described. Herein, the most common trifluoromethyl source, (trifluoromethyl)trimethylsilane, was converted selectively into “trifluoromethyl copper” by using copper iodide as copper source and potassium fluoride as promoter. In 1,3‐dimethyl‐3,4,5,6‐tetrahydro‐2(1H)‐pyrimidinone (DMPU) as chelating solvent the trifluoromethylation of activated and non‐activated alkenyl halides occurred mostly in good to excellent yields in up to a gram scale.
Self‐Assembling and Size‐Selective Synthesis of Ni and NiO Nanoparticles Embedded in Ordered Mesoporous Carbon and Polymer Frameworks
Authors: Wang Wei , Wang Hai‐yan , Wei Wei , Xiao Zhi‐Guang , Wan Ying
Published: October 2011

We demonstrate the self‐assembling and size‐selective synthesis of uniform and highly dispersed Ni or NiO nanoparticles with diameters below 12 nm embedded in ordered mesoporous carbon or polymer frameworks. Self‐assembly is induced by evaporation of the solvent from a mixture of metal‐containing liquid crystalline (LC) mesophases of triblock copolymer and transition metal nitrate hydrate, and the carbon source is low‐polymerized phenolic resol. Characterization by XRD, N2 sorption isotherms, TEM, HRSEM, ICP‐AES, TG, and XPS techniques has indicated an ordered 2D hexagonal mesostructure, high surface areas between 524 and 721 m2 g−1, uniform pore sizes of about 4.0 nm, large pore volumes ranging from 0.34 to 0.58 cm3 g−1, and metal contents ranging from 0.6 to 10.0 wt %. There is a high degree of dispersion, and a small size of nanoparticles throughout the whole framework, without aggregation outside of the pores due to the confinement effect of the mesoporous ordered matrix. The mesoporous solids show excellent adsorption properties for dyes and permit an easy magnetic separation procedure. This method is expected to be applicable to other mesoporous transition metal(oxide)‐containing carbon catalysts.
Synthesis and Structural Characterization of Homochiral Homo‐oligomers of Parent cis‐ and trans‐Furanoid‐β‐Amino Acids
Authors: Pandey Sunil K. , Jogdand Ganesh F. , Oliveira João C. A. , Mata Ricardo A. , Rajamohanan Pattuparambil R. , Ramana Chepuri V.
Published: October 2011

The synthesis of homochiral homo‐oligomers of cis‐ and trans‐3‐aminotetrahydrofuran‐2‐carboxylic acids (parent cis‐ and trans‐furanoid‐β‐amino acids, referred to as “cis‐/trans‐FAA”) has been carried out to understand their secondary structures and their dependence on the ring heteroatom. The oligomers of two diastereomers have been shown to have a distinct left‐handed helicity. The cis‐FAA homo‐oligomers show a 14‐helix structure, in contrast to the homo‐oligomers of cis‐ACPC, which adopt a sheet like structure. The trans‐FAA homo‐oligomers were found to adopt a 12‐helix structure, the same trend found in trans‐ACPC homo‐oligomers. With the help of ab initio calculations, the structural features of cis‐ACPC and cis‐FAA hexamers were compared. We believe that the more compact packing of the cis‐FAA hexapeptide should be due to a more favorable interaction between the ring and the backbone amide hydrogen.
Synthesis of Chondramide A Analogues with Modified β‐Tyrosine and Their Biological Evaluation
Authors: Zhdanko Alexander , Schmauder Anke , Ma Christopher I. , Sibley L. David , Sept David , Sasse Florenz , Maier Martin E.
Published: October 2011

Starting from cinnamates9, obtained by Wittig reaction or Heck coupling, the diols17were prepared by asymmetric dihydroxylation. This was followed by a regioselective substitution of the 3‐OH group with hydrazoic acid under Mitsunobu conditions. Methylation of the 2‐OH group and reduction of the azide group led to the β‐tyrosine derivatives8. Condensation with the dipeptide acid6furnished the tripeptide part of the chondramides. The derived acids21were combined with the hydroxy ester7to the esters22. Cleavage of thetert‐butyl groups and intramolecular lactam formation gave rise to the chondramide A analogues2 b–k. Growth inhibition assays showed most of the analogues to be biologically active. Some of them even reach the activity of jasplakinolide. It can be concluded that the 4‐position of the aryl ring in the β‐tyrosine of chondramide A tolerates structural modifications quite well.
Total Synthesis of Pamamycin‐649B
Authors: Fischer Petra , Gruner Margit , Jäger Anne , Kataeva Olga , Metz Peter
Published: October 2011

The first total synthesis of the macrodiolide antibiotic pamamycin‐649B (1) was achieved by using sultone methodology. The diethyl substituted larger hydroxy acid fragment was constructed in a concise fashion through domino elimination/alkoxide‐directed 1,6‐additions of ethyllithium to sultones derived from intramolecular Diels–Alder reaction of furan‐containing vinylsulfonates. Intermolecular Yamaguchi esterification of the two hydroxy acid building blocks and subsequent Yamaguchi cyclization eventually provided the target macrocycle 1. Since the final lactonization with formation of the ester linkage between C1′ and the C8 oxygen proceeded with complete C2′ epimerization, the more readily available C2′ epimeric smaller fragment could be used to streamline the synthetic sequence.
ChemInform Abstract: Facile Routes to ThIV, UIV, and NpIV Phosphites and Phosphates.
Authors: Villa Eric M. , Wang Shuao , Alekseev Evgeny V. , Depmeier Wulf , Albrecht‐Schmitt Thomas E.
Published: October 2011

Compounds (III), (V), and (VII) are characterized by single crystal XRD and UV/VIS/NIR spectroscopy.
ChemInform Abstract: Solvent‐Free Aerobic Oxidation of Alcohols with 1‐Methyl‐2‐azaadamantane N‐Oxyl as a Recyclable Catalyst Through Phase Separation.
Authors: Kuang Yongbo , Nabae Yuta , Hayakawa Teruaki , Kakimoto Masa‐aki
Published: October 2011

The catalyst can be used several times and is in this regard recycled by phase separation.
ChemInform Abstract: Catalytic Decarboxylative Alkylation of β‐Keto Acids with Sulfonamides via the Cleavage of Carbon—Nitrogen and Carbon—Carbon Bonds.
Authors: Yang Cui‐Feng , Wang Jian‐Yong , Tian Shi‐Kai
Published: October 2011

A range of β‐keto acids smoothly undergo decarboxylative alkylations with N‐benzylic or N‐allylic sulfonamides in the presence of FeCl3 to afford structurally diverse unsymmetric ketones in good to excellent yields and with extremely high regioselectivity.
ChemInform Abstract: Molybdenum Hexacarbonyl Mediated Alkoxycarbonylation of Aryl Halides.
Authors: Ren Wei , Emi A. , Yamane Motoki
Published: October 2011

The simple procedure allows the reaction of a variety of alcohols with aryl bromides and iodides applying Mo(CO)6 as the CO source.
ChemInform Abstract: Conia‐ene Annulation of the α‐Cyano β‐TMS‐Capped Alkynyl Cycloalkanone System and Its Synthetic Application.
Authors: Chin Chih‐Lung , Liao Cheng‐Feng , Liu Hsing‐Jang , Wong Ying‐Chieh , Hsieh Ming‐Tsang , Amancha Prashanth K. , Chang Chun‐Ping , Shia Kak‐Shan
Published: October 2011

The title reaction affords a variety of bicyclic silylmethylene‐substituted cyclopentane derivatives.
ChemInform Abstract: Broensted Acid Catalyzed Reductive Amination with Benzothiazoline as a Highly Efficient Hydrogen Donor.
Authors: Zhu Chen , Akiyama Takahiko
Published: October 2011

Benzothiazolines are used as reducing agent in a novel appoach.
ChemInform Abstract: Synthesis of Unsymmetrical Benzils Using N‐Heterocyclic Carbene Catalysis.
Authors: Suzuki Yumiko , Bakar Abu Md. , Tanoi Takashi , Nomura Naoko , Sato Masayuki
Published: October 2011

The benzils (21 examples) are prepared under optimized conditions by nucleophilic aroylation of benzimidoyl chlorides with aromatic aldehydes followed by acid‐promoted hydrolysis of the resulting iminoethanones.
ChemInform Abstract: Imidazole‐Coordinated Monodentate NHC—Pd(II) Complex Derived from Proline and Its Application to the Coupling Reaction of Arylboronic Acids with Carboxylic Acid Anhydrides in Water at Room Temperature.
Authors: Shen Xiao‐Bao , Gao Ting‐Ting , Lu Jian‐Mei , Shao Li‐Xiong
Published: October 2011

In the presence of a new complex, cross‐coupling reaction of arylboronic acids with carboxylic acid anhydrides results in formation of diarylketones, mostly in high yields.
ChemInform Abstract: Efficient Organocatalytic Dual Activation Strategy for Preparing the Versatile Synthons (2E)‐1‐(Het)Aryl/styryl‐3‐(dimethylamino)prop‐2‐en‐1‐ones and α‐(E)‐[(Dimethylamino)methylene]cycloalkanones.
Authors: Bindal Sachin , Kumar Dinesh , Kommi Damodara N. , Bhatiya Sonam , Chakraborti Asit K.
Published: October 2011

Optimized reaction conditions using 2‐guanidinoacetic acid as the catalyst are developed for the condensation of methyl ketones or cycloketones with acetal (II) to give E‐isomers of enaminones.
ChemInform Abstract: Efficient Synthesis of Substituted Polyarylphthalimides via Cycloaddition of Cyclopentadienones with 2‐Bromomaleimide.
Authors: Vanel Remi , Berthiol Florian , Bessieres Bernard , Einhorn Cathy , Einhorn Jacques
Published: October 2011

The reaction allows a general access to functionalized phthalimide structures and thus opens the way to new organocatalysts in areobic oxidation.
ChemInform Abstract: Synthesis of Nucleoside Analogues in a Ball Mill: Fast, Chemoselective and High Yielding Acylation Without Undesirable Solvents.
Authors: Ravalico Francesco , James Stuart L. , Vyle Joseph S.
Published: October 2011

The yields of the presented approach are equal to or greater than conventional DMF‐based methods.
ChemInform Abstract: Oxidative Fragmentation of Oxiranes to Nitriles with Hypervalent Iodine(V) Reagents in Aqueous Ammonia.
Authors: Deshmukh Swapnil S. , Huddar Sameerana N. , Jadhav Ravindra R. , Akamanchi Krishnacharya G.
Published: October 2011

Nucleophilic ring‐opening of the starting epoxides with aqueous ammonia followed by oxidation of the intermediate amino alcohol with IBX results in formation of the corresponding nitriles.
ChemInform Abstract: Practical Synthesis of 2‐Arylacetic Acid Esters via Palladium‐Catalyzed Dealkoxycarbonylative Coupling of Malonates with Aryl Halides.
Authors: Song Bingrui , Rudolphi Felix , Himmler Thomas , Goossen Lukas J.
Published: October 2011

Two complementary protocols are developed, one of which is optimal for electron‐rich, the other for electron‐poor and sterically demanding aryl halides.
ChemInform Abstract: An Umpolung Sulfoxide Reagent for Use as a Functional Benzyl Carbanion Equivalent.
Authors: Pinna Giovanni , Belluci Maria Cristina , Malpezzi Luciana , Pisani Laura , Superchi Stefano , Volonterio Alessandro , Zanda Matteo
Published: October 2011

A new family of umpolung sulfoxide reagents for the synthesis of α‐benzyl alcohols, chlorides, and acetamides is developed.
ChemInform Abstract: One‐Pot Synthesis of Fused‐Tetracyclic Scaffolds Employing a Lewis Acid Promoted Domino Reaction of Naphthoquinones.
Authors: Bendiabdellah Yassine , Villanueva‐Margalef Isabel , Misale Antonio , Nahar Kazi S. , Haque Mohammad R. , Thurston David E. , Zinzalla Giovanna
Published: October 2011

The reaction of substrates (I) with hydroxy‐ and amino‐functionalized cross‐conjugated trienes involves a cascade of heterocyclization via hemiacetal or imine formation, and intramolecular Diels—Ader reaction to provide access to polycyclic (heterocyclic) frameworks.
ChemInform Abstract: Synthesis of 4‐Aryl‐2(5H)‐furanones by Gold(I)‐Catalyzed Intramolecular Annulation.
Authors: Sun Haifeng , Huang He , Zhang Dengyou , Feng Enguang , Qian Wangke , Zhang Lei , Chen Kaixian , Liu Hong
Published: October 2011

The title reaction is carried out under mild conditions and shows excellent tolerance to various functional groups.
ChemInform Abstract: Synthesis, Cytotoxicity and Topoisomerase II Inhibitory Activity of Benzonaphthofurandiones (V).
Authors: Rhee Hee‐Kyung , Kwon Youngjoo , Chung Hwa‐Jin , Lee Sang Kook , Choo Hea‐Young Park
Published: October 2011

All the dihydroxy derivatives, e.g. (Va)—(Vd), exhibit relatively potent cytotoxicity.
ChemInform Abstract: A New One‐Pot Synthesis of Polysubstituted Indoles from Pyrroles and β‐Nitroacrylates.
Authors: Palmieri Alessandro , Gabrielli Serena , Lanari Daniela , Vaccaro Luigi , Ballini Roberto
Published: October 2011

An innovative procedure under mild conditions is presented.
ChemInform Abstract: Manganese Chloride as an Efficient Catalyst for Selective Transformations of Indoles in the Presence of a Keto Carbonyl Group.
Authors: Li Minghao , Yang Jie , Gu Yanlong
Published: October 2011

MnCl2 (and MnBr2) is proved to be an effective catalyst for selective transformations of indoles, ring‐opening reaction of dihydropyrans, transesterification of β‐keto ester and multicomponent reactions.
ChemInform Abstract: Phenylboronic Acid Catalyzed—Cyanide‐Promoted, One‐Pot Synthesis of 2‐(2‐Hydroxyphenyl)benzoxazole Derivatives.
Authors: Lopez‐Ruiz Heraclio , Briseno‐Ortega Horacio , Rojas‐Lima Susana , Santillan Rosa , Farfan Norberto
Published: October 2011

The generality of the mild and efficient procedure is shown by synthesis of 19 derivatives of type (II) and (V) and extension to the preparation of methylene bis‐benzoxazoles (VIII).
ChemInform Abstract: Synthesis and Biological Activities of 2‐Amino‐thiazole‐5‐carboxylic Acid Phenylamide Derivatives.
Authors: Zhou Jinpei , et al. et al.
Published: October 2011

The compounds (VII) are evaluated for growth inhibitory activity against MCF‐7 and MDA‐MB 231 breast cancer and HT‐29 colon cancer cell lines.
ChemInform Abstract: A Straightforward Synthesis of 2‐Aminobenzothiazoles from Herz Compounds.
Authors: Neo Ana G. , Carrillo Rosa M. , Marcos Carlos F.
Published: October 2011

The key step consists of an iodine‐catalyzed insertion of aliphatic or aromatic isocyanides into the S—S bond of benzodithiazolones (I) which is accompanied by extrusion of sulfur monoxide.
ChemInform Abstract: A Facile Synthesis of New Troponoid‐Bearing Flavonoid‐Like Compounds.
Authors: Chang Mingqin , Li Yang , Gao Wentao
Published: October 2011

The presented synthesis of the title compounds (IV) involves the Claisen—Schmidt condensation.
ChemInform Abstract: FeCl3·6H2O‐Catalyzed Synthesis of Substituted cis‐2,6‐Tetrahydropyrans from ξ‐Hydroxy Allylic Derivatives.
Authors: Guerinot Amandine , Serra‐Muns Anna , Bensoussan Charlelie , Reymond Sebastien , Cossy Janine
Published: October 2011

The geometry of the substrate double bond does not affect the outcome of the reaction and both phenyl and mesityl groups are well tolerated.
ChemInform Abstract: Enantioselective Synthesis of 2‐Aryl‐3‐nitro‐2H‐chromenes Catalyzed by a Bifunctional Thiourea.
Authors: Zhang Zhiguo , Jakab Gergely , Schreiner Peter R.
Published: October 2011

A range of nitrostyrenes undergoes a tandem oxa‐Michael‐aza‐Henry desulfonamidation process with salicyl N‐tosylimines to permit an enantioselective synthesis of the target compounds.
ChemInform Abstract: Synthesis of 4‐Hydroxy‐4H‐chromenes by Reaction of Salicylic Aldehydes with Alkynals Catalyzed by Silyl Prolinol Ethers.
Authors: Aleman Jose , Alvarado Cuauhtemoc , Marcos Vanesa , Nunez Alberto , Garcia Ruano Jose Luis
Published: October 2011

Optimized conditions are developed which produce the desired hydroxychromenes as structural motifs of natural compounds either with higher yield and lower e.e.
ChemInform Abstract: Organocatalytic Asymmetric Synthesis of Functionalized 4H‐Chromenes via a One‐Pot Domino Michael‐Hemiacetalization and Dehydration Sequence.
Authors: Enders Dieter , Urbanietz Gregor , Raabe Gerhard
Published: October 2011

The procedure allows the preparation of the synthetically important skeleton with in part excellent enantioselectivity.
ChemInform Abstract: Synthesis of Fluorescence Pyriproxyfen Analogues as Juvenile Hormone Agonists.
Authors: Abe Hideki , Sato Akimi , Tokishita Shin‐ichi , Ohta Toshihiro , Ito Hisanaka
Published: October 2011

The fluorescence properties of the synthetic analogues (III) are investigated.
ChemInform Abstract: An Efficient Route to 1‐Aminoisoquinolines via AgOTf‐Catalyzed Reaction of 2‐Alkynylbenzaldoxime with Amine.
Authors: Zheng Danqing , Chen Zhiyuan , Liu Jianping , Wu Jie
Published: October 2011

The presence of PPF is essential for a successful performance of the title reaction.
ChemInform Abstract: Enantioselective Synthesis of Quinolizidines and Indolizidines via a Catalytic Asymmetric Hydrogenation Cascade.
Authors: Rueping Magnus , Hubener Lukas
Published: October 2011

The asymmetric reductive cyclization of aryl‐3‐quinolinylbutenones (I) is not complete after the first step and requires an additional reduction via catalytic hydrogenation.
ChemInform Abstract: Synthesis of Aza Coumarins by Nucleophilic Addition of Acetylenic Esters Catalyzed by Ph3P.
Authors: Mohtat Bita , Yavari Issa , Ameri Roza E. , Salahi Elnaz
Published: October 2011

Under neutral conditions, a mixture of functionalized aza‐coumarins is obtained.
ChemInform Abstract: Facile Synthesis of Tricyclic Oxazino‐ or Oxazepino‐Fused Tetrahydroquinolines via Intramolecular Reductive Amidation.
Authors: Mondal Shyamal , Maity Arindam , Naskar Subhendu , Paira Rupankar , Hazra Abhijit , Sahu Krishnendu B. , Saha Pritam , Das Saktipada , Banerjee Sukdeb , Mondal Nirup B.
Published: October 2011

Treatment of esters (I) and (III) with zinc in acetic acid allows formation of title compounds (II) and (IV) under environmentally friendly mild conditions.
ChemInform Abstract: Convergent and Stereodivergent Synthesis of Complex 1‐Aza‐7‐oxabicyclo[2.2.1]heptanes.
Authors: Yang Dexi , Micalizio Glenn C.
Published: October 2011

Densely functionalized tri‐ and tetrasubstituted title compounds such as (V) and (IX) or their enantiomerically pure analogues are prepared following a sequence defined by a new diastereoselective synthesis of (E)‐anti‐homoallylic primary amines, N‐oxidation and stereodivergent nitrone annulation.
ChemInform Abstract: Highly Efficient Ag(I)‐Catalyzed Regioselective Tandem Synthesis of Diversely Substituted Quinoxalines and Benzimidazoles in Water.
Authors: Rustagi Vineeta , Aggarwal Trapti , Verma Akhilesh K.
Published: October 2011

The presented reaction procedure provides the desired products with high regioselectivity under environmentally benign conditions.
ChemInform Abstract: Synthesis, Cytotoxicity Testing, and Structure—Activity Relationships of Novel 6‐Chloro‐7‐(4‐phenylimino‐4H‐3,1‐benzoxazin‐2‐yl)‐3‐ (substituted)‐1,4,2‐benzodithiazine 1,1‐Dioxides.
Authors: Pomarnacka Elzbieta , Kornicka Anita , Kuchnio Anna , Heinrichs Maike , Gruenert Renate , Gdaniec Maria , Bednarski Patrick J.
Published: October 2011

The title compounds are tested of their cytotoxic activity against 6 human cancer cell lines.
ChemInform Abstract: Efficient Synthesis, Structural Characterization and Antimicrobial Activity of Chiral Aryl Boronate Esters of 1,2‐O‐Isopropylidene‐α‐D‐xylofuranose.
Authors: Trivedi Rajiv , Reddy E. Rami , Kumar Ch. Kiran , Sridhar B. , Kumar K. Pranay , Rao M. Srinivasa
Published: October 2011

Starting from the known protected α‐D‐xylofuranose (I), a simple and efficient approach towards a series of chiral aryl boronate esters (III) is described.
ChemInform Abstract: Chemistry of Phosphorus Ylides. Part 33. Synthesis and Antitumor Activities of Some New Chromenone Derivatives.
Authors: Maigali Soher S. , Abd‐El‐Maksoud Mansoura A. , Soliman Fouad M.
Published: October 2011

The reactions of the compounds (II) and (VI) with different chromenones (I), (IV), (VIII), and (XII) lead to the formation of new chromenone derivatives, which have carbocycles and heterocycles of various ring sizes and heteroatom patterns as substituents.
ChemInform Abstract: Asymmetric aza‐Michael Addition under Ultra‐High Pressure: Short Bias to Polyhydroxylated Piperidines.
Authors: Moura Sidnei , Thomassigny Christine , Ligeour Caroline , Greck Christine , Joseph Delphine , Drege Emmanuelle , Dumas Francoise
Published: October 2011

Compounds (I) are prepared from commercial sugars by a Wittig olefination approach.
ChemInform Abstract: exo‐Cyclopamine — A Stable and Potent Inhibitor of Hedgehog‐Signaling.
Authors: Heretsch Philipp , Buettner Anita , Tzagkaroulaki Lito , Zahn Stefan , Kirchner Barbara , Giannis Athanassios
Published: October 2011

The compound (I) is a stable and tenfold more potent inhibitor of hedgehog‐signaling than its parent cyclopamine.
ChemInform Abstract: Efficient Access to a Dihydropyran‐Containing Macrolide via a Transannular Oxy‐Michael Reaction: Total Synthesis of (+)‐Aspergillide C.
Authors: Kobayashi Hisataka , Kanematsu Makoto , Yoshida Masahiro , Shishido Kozo
Published: October 2011

An enantioselective total synthesis of the title compound (II) involves the shown key step via a transannular oxy‐Michael reaction.