bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Modelling Technique on Interactivity between Human Carbonic Anhydrase 1 and Mangiferin for Antiulcer activity
Authors: Das Paramita , Nayak Anjali , K Bhavani , Deepika Deepika , Ranjitha Ranjitha , Md Afsar
Published: July 2023

Mangiferin is obtained naturally from Mangifera indica which is used in treating various diseases including gastrointestinal tract diseases. Ulcer means the damage of the mucosal membrane which commonly occurs in the stomach and upper duodenum. In the study, an antiulcer activity was conducted and the interactivity of human carbonic anhydrase 1 was studied. The human carbonic anhydrase 1 enzyme belonging proteins were taken in the study for the molecular docking. It was observed that mangiferin showed better activity in treating ulcers. The human carbonic anhydrase enzyme also mentioned as CA1 is one of the major reasons for an increase in gastric acid which leads to ulcers. In this study, mangiferin was able to inhibit the action of the CA1 enzyme which was increasing the levels of hydrochloric acid and preventing the formation of ulcers. A protein of CA1 (PDB ID: 6G3V) was docked with mangiferin which showed good interaction with the mangiferin. Further albino rats were used for the study of ulcer activity. ADMET studies were performed for mangiferin which showed a low toxic effect. A detailed study has been depicted for ulceration and its prevention using mangiferin.
A new stability indicating HPLC and LC-APCI-MS methods for the estimation of Clofarabine in pharmaceutical dosage forms
Authors: Aluri Sai Gnaneswari , Mathrusri Annapurna Mukthinuthalapati
Published: July 2023

Clofarabine is an anti-cancer drug. A new stability indicating isocratic RP-HPLC and LC-APCI-MS methods have been developed and validated for the quantification of Clofarabine as per ICH guidelines. Thermo scientific-TSQ Quantis with Vanquish HPLC coupled with MS was employed for the present study. Simpack C18 column was used for chromatographic resolution and a triple quadrupole mass spectrometer with atmospheric pressure chemical ionization (APCI) source, running in the positive mode (as well as negative mode) was used for detection. A mixture of 0.1% Formic acid: Acetonitrile was used as mobile phase on gradient mode and a mixture of Methanol: Water (50:50, v/v) was used as diluent. A wide linearity concentration range 5.0-150 μg/mL was shown by the proposed method. The proposed methods are simple, precise, and accurate are used to quantify the marketed formulations of Clofarabine. Stress degradation studies were performed and the method is found to be selective and specific.
Application of Dental Age Estimation: A Review
Authors: Walia Megha , Bhati Kajol , Gullaiya Jyoti
Published: July 2023

Age estimation is a vital method in odontopediatrics, legitimate pharmaceutical, anthropology, pediatrics, orthodontics, and forensic sciences, and is conducted for vast variety of reasons. Its use is expanding in both civil and criminal things and is also to identify person in mass disasters and natural calamities. A number of anthropologists have examined the age frameworks, wherein age is frequently a major establishing guideline. Dental-age assessment is considered most a precise, solid, and quick strategy of age assurance, particularly in developing children and is considered exceptionally critical in numerous fields of study.
Thực trạng và biện pháp phát triển đội ngũ cán bộ quản lý trường tiểu học ở thị xã Chơn Thành, Tỉnh Bình Phước
Authors: Trần Thị Mến
Published: July 2023

Đội ngũ cán bộ quản lý giữ vai trò quan trọng trong việc nâng cao chất lượng giáo dục. Bài viết nghiên cứu về thực trạng và sự phát triển của đội ngũ cán bộ quản lý các trường tiểu học ở thị xã Chơn Thành, tỉnh Bình Phước về số lượng, cơ cấu và chất lượng. Trên cơ sở đó, tác giả đề xuất biện pháp phát triển đội ngũ cán bộ quản lý các trường tiểu học ở thị xã Chơn Thành trong thời gian tới nhằm góp phần nâng cao chất lượng giáo dục trên địa bàn thị xã.
Construction and Analysis of Items for Assessing Learning Outcomes: Concise Models for Ensuring Validity
Authors: Ofori Bekoe Samuel
Published: July 2023

How can we effectively tell whether learners have acquired, and can exhibit outcomes that were initially established for them, and instructions tailored to? This question leads to assessment of learning outcomes or instructional results. It is for instance held that an outcomes-based approach to this requires assessment, in authentic ways, of what is considered to be most important of students’ attainments. Unfortunately, the use of inappropriate assessment/test items/instruments is a widespread phenomenon and has become a practice/malpractice most urgently in need of improvement. To ensure such improvement is to satisfy the most important criteria in assessment/test administration; validity. The prevailing assessment culture is however still steeped in the pre-occupation with reliability. This is due to the notion that for an assessment to be reliable it must first be valid, and the subsequent assumption that the reliability of an assessment invariably ensures its validity, as there is no structured/formulaic way of determining validity. It is however known that an assessment can be reliable without necessarily being valid. This paper therefore attempts to fill this validity void, by presenting two well-structured models/flowcharts; one, for verifying the validity or usefulness/appropriateness of assessment items and the other for the construction/writing of valid/appropriate assessment items.
Increased productivity of maize (Zea mays L.) through ear-to-row selection
Authors: Ach. Supyanto  , Suhartono  , Achmad Amzeri
Published: July 2023

Assembling superior maize varieties is one of the strategies to increase maize productivity on suboptimal land on Madura Island, Indonesia. One method of assembling high-yielding maize varieties is ear-to-row selection. The research aimed to determine the genetic advances due to ear-to-row selection on the Tambin, Sukmaraga, and Srikandi Kuning varieties. The research was carried out in two stages of activity. Stage 1, carrying out ear-to-row selection for one cycle from the C0 population to form a C1 population. Ear-to-row selection was done on three varieties: the Tambin, Sukmaraga, and Srikandi Kuning. Stage II, carried out an evaluation of the C0 and C1 populations on the three varieties so that six populations were produced. Population evaluation used a completely randomized block design with three replications, resulting in 18 experimental units. Observational variables include ear length, ear diameter, seeds number per row, weight of 100 seeds, seed weight per ear, and production per hectare. The results showed that ear-to-row selection on maize varieties Tambin, Sukmaraga, and Srikandi Kuning showed significantly different selection progress based on the t-test at 5% on maize production per hectare. Heritability values ​​in a broad sense for all characters observed in the moderate to high categories of the three varieties (Tambin, Sukmaraga, and Srikandi Kuning).
THE OUTPUT NOISE REDUCTION OF THE R-2R RESISTOR LADDER DIGITAL-ANALOG CONVERTER
Authors: BABAJANYAN H.A.
Published: July 2023

A new method for reducing output noises in the R-2R resistor ladder digital-analog converter (DAC) is presented. The main reason for the output noises in R-2R resistor ladder DAC is the disadvantages and non-ideal features of the operational amplifier (Op-Amp). In case of the low numbers of the input combination there can be an output voltage without noises, because the voltage-error for the OpAmp in case of low output voltage is very small. But the low output voltage can be not the exact voltage because many times the 0 voltage on the negative input of the OpAmp forms is not clear. The high output voltage of the OpAmp can be more exact, but it will have noises because of the conflict between the voltage corresponding to the difference of the input voltages and the voltage corresponding to the current coming from the R-2R ladder. Using the new method, the output voltage of the R-2R resistor ladder DAC will be exactly in the full input combination range, and it will have almost no noise. In the primary 4-bit R-2R DAC designed in the 32 nm technology the INL (integral nonlinearity error) in case of 0000 input combination is 0.2 V, and the noise-error in case of 0101 input combination is 0.065 V. In the optimized R-2R DAC, the maximum INL error is 0.02 V at 0010 input combination and the maximum noise-error is 0.005 V at 0001 input combination. Using the method, the area of the circuit increases by 7%. As this disadvantage is very small the new approach is very preferable to use for accurate output signal in the R-2R resistor ladder DAC.
THE EYE OPENING IMPROVEMENT METHOD FOR A HIGH SPEED CURRENT MODE LOGIC DRIVER
Authors: GRIGORYAN H.T.
Published: July 2023

A bandwidth improvement method of current mode logic (CML) drivers, of the integral circuit type specifically designed for high-speed serial data transmission systems is presented. These drivers are characterized by their ability to operate at high frequencies and their ability to provide a high level of signal integrity, which is critical for achieving high data rates and low error rates in high-speed systems. The key advantages of CML drivers such as providing a high level of signal integrity, the circuit topologies, operating modes, and performance characteristics are discussed. Furthermore, the challenges and limitations of CML drivers, as well as the recent advances in the field that enables the use of CML drivers in high-speed systems are also discussed. A driver constructed by the proposed method operating at 112 Gbps in PAM4 modulation consumes 9 mW under 0.9 V supply.
Hepatoprotective effect of Vernonia amygdalina and Ocimum gratissimum on Wistar rats exposed to long-term administration of artemisinin-based combination therapies
Authors: Melvin Nnaemeka Ugwu
Published: July 2023

In this study the protective effect of Vernonia amygdalina (VA) and Ocimum gratissimum (OG) on rats exposed to long term oral administration of artesunate-amodiaquine and arthemeter-lumefantrine were investigated. Forty-two albino rats were divided into seven groups. They were given the drugs, artesunate amodiaquine (AA) and artemether lumefantrine (AL) base on their body weight. Group 1: Control, received distilled water, group 2, received of 2.86 mg/7.7 mg AA, group 3, received of 1.14 mg/6.86 mg AL, group 4 received of 2.86 mg/7.7 mg AA + 200 mg VA, group 5 received of 1.14 mg/6.86 mg AL + 200 mg VA, group 6 received of 2.86 mg/7.7 mg AA + 200 mg OG and group 7 received of 1.14 mg/6.86 mg AL + 200 mg OG. The animals were sacrificed and blood samples obtained through cardiac puncture for biochemical investigations. Biochemical assay for total protein, albumin, total bilirubin, direct bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyltransferase (γ-GT) were done. Co-administration of artesunate-amodiaquine and arthemeter-lumefantrine significantly decreased (P< 0.05) total protein and albumin while there was significant increase (P< 0.05) in total bilirubin, direct bilirubin, AST, ALT, ALP and γ-GT when compared with control group. The administration of VA and OG significantly increased the total protein and albumin and significantly decreased (P< 0.05) total bilirubin and liver enzymes when compared with control group. The results indicate hepatic injury in the rats exposed to long term administration of artemisinin-based combination therapies (ACTs) which was reversed by the administration of VA and OG. There is need for caution while taking ACTs as malaria chemotherapy.
The intraocular pressure reducing- potential of topically administered aqueous extract of Dennetia Tripetala on Wistar strain albino rats
Authors: Chigozie John Ekenze  , Magnus Chinonye Nsonwu  , Lilian Chioma Owunna  , Jacqueline Obioma-Elemba  , Timothy Olugbenga Ogundeko
Published: July 2023

The second section of manuscript should contain Abstract and Keywords. Abstract should be informative, self-explanatory and easy to understand. Plant parts have continued to attract attention in the global search for the treatment of many diseases affecting humans. Dennetia tripetala (mmimi) is a well-known spicy indigenous forest fruit from the family annonacea and has been found to contain lots of minerals, vitamins, alkaloids and trace elements which are of medicinal importance. This study investigated the effect of topical ripe and unripe Dennetia tripetala seed extracts on the intraocular pressure of albino Wistar rats. Fifteen healthy male albino Wistar rats were used for the study. The rats were randomly divided into 3 groups (A, B, C), each group consisting of 5 rats. Group A rats were treated with one drop of ripe seed extract in their right eye and one drop of Timolol eye drop in their left eye. Group B rats received one drop of unripe seed extract in their right eye and one drop of Timolol eye drop in their left eye. Group C rats served as control (received one drop of water in OD). The I0P of each rat was measured pre and post instillation of one drop volume of the solutions at 30 mins interval for 120 minutes. The findings showed peak reduction of IOP after 60 mins (6.02 mmHg, representing 31.2 % reduction) of instillation one drop volume of ripe D. tripetala seed extract and reverted towards baseline (19.16 mmhg). The peak effect of ripe D. tripetala was found to be statistically significant (P =4.558). Unlike ripe D. tripetala seed extract, the unripe extract induced consistent IOP reduction till 120 minutes (5 % after 30 minutes, 16.5 % after 60minutes and 17.9 % after 120 minutes) from the baseline (18.84 mmHg). The reduction in IOP after 60 minutes (P = .4145) and 120 minutes was statistically significant (P= 2.5448). When compared with Timolol, Timolol produced steady and highest IOP reduction (15 %, 23.5 %, and 33.3 % from the baseline) 30 minutes, 60 minutes and 120 minutes post instillation respectively. Topical administration of aqueous extract of ripe D. tripetala seed significantly reduced intraocular pressure in albino Wistar rats, suggesting anti-glaucoma effect of the extract.
Rezension von: Manecke, Wolfgang; Vogl, Mark, Historische Orgeln im Dreiländerkreis Sigmaringen
Authors: Höflacher Ulrich , Manecke Wolfgang , Vogl Mark
Published: July 2023

Wolfgang Manecke/Mark Vogl: Historische Orgeln im Dreiländerkreis Sigmaringen. Mit einem Inventar aller bekannten Pfeifenorgeln in den Kirchen des Landkreises. Heimatliche Schriftenreihe des Landkreises Sigmaringen Bd. 12. Meßkirch 2010. 288 S. mit zahlreichen farbigen Abbildungen, 24,90 EUR.
Rezension von: Heimatmuseum Reutlingen (Hrsg.), Figuren des Heils
Authors: Leistenschneider Eva , Heimatmuseum Reutlingen
Published: July 2023

Heimatmuseum Reutlingen/Werner Stöbele (Hg.): Figuren des Heils. Gotische Kunst aus Reutlingen. Begleitheft zur gleichnamigen Ausstellung im Heimatmuseum Reutlingen vom 22. November 2009 bis 7. Februar 2010. Reutlingen 2009. 75 S., zahl. Abb., 10,50 EUR
Rezension von: Kommission für geschichtliche Landeskunde in Baden-Württemberg (Hrsg.), Die Investiturprotokolle der Diözese Konstanz aus dem 16. Jahrhundert
Authors: Schöllkopf Wolfgang , In Baden-Württemberg Kommission für Geschichtliche Landeskunde
Published: July 2023

Kommission für geschichtliche Landeskunde in Baden-Württemberg (Hg.): Die Investiturprotokolle der Diözese Konstanz aus dem 16. Jahrhundert (Veröffentlichungen der Kommission für geschichtliche Landeskunde in Baden-Württemberg, Reihe A: Quellen 48/I und II und 49). Stuttgart: Kohlhammer Verlag 2008-2010; 514 S., 578 S. und 845 S. und Karte, geb., 45,00 EUR, 45,00 EUR und 60,00 EUR.
Rezension von: Ehmer, Hermann, Die Reformation in Schwaben
Authors: Litz Gudrun , Ehmer Hermann
Published: July 2023

Hermann Ehmer: Die Reformation in Schwaben (Bibliothek Schwäbischer Geschichte 2). Leinfelden-Echterdingen: DRW-Verlag 2010; 202 S. (und 40 S. Anhang), zahlr. s/w-Abb., brosch., 14,90 EUR
Rezension von: Sailer, Sebastian, Triduum Sacrum
Authors: Scheinhammer-Schmid Ulrich , Sailer Sebastian
Published: July 2023

Sebastian Sailer: Triduum Sacrum oder Dreitägige Exerzitien. Lateinisch-Deutsch. Aus dem Lateinischen übersetzt und kommentiert von Ulrich Fischer (Bibliotheca suevica 25). Konstanz-Eggingen: Edition Isele 2008. 472 S., geb., 25,00 EUR
Rezension von: Hepach, Wolf-Dieter; Adler, Wolfgang, Flugpioniere in Ulm
Authors: Palaoro Simon , Hepach Wolf-Dieter , Adler Wolfgang
Published: July 2023

Wolf-Dieter Hepach/Wolfgang Adler: Flugpioniere in Ulm 1811-1911 (Kleine Reihe des Stadtarchivs Ulm 8). Ulm: Klemm & Oelschläger 2010. 120 S., zahl. Abb., brosch., 17,80 EUR
Rezension von: Köhlerschmidt, Antje; Neidlinger, Karl (Hrsg.), Die jüdische Gemeinde Laupheim und ihre Zerstörung
Authors: Eitel Peter , Köhlerschmidt Antje , Neidlinger Karl
Published: July 2023

Antje Köhlerschmidt/Karl Neidlinger (Hg.): Die jüdische Gemeinde Laupheim und ihre Zerstörung. Biografische Abrisse ihrer Mitglieder nach dem Stand von 1933. Laupheim 2008; 592 Seiten, 29.80 EUR
Rezension von: Weber, Edwin Ernst (Hrsg.), Opfer des Unrechts
Authors: Eitel Peter , Weber Edwin Ernst
Published: July 2023

Edwin Ernst Weber (Hg.): Opfer des Unrechts. Stigmatisierung, Verfolgung und Vernichtung von Gegnern durch die NS-Gewaltherrschaft an Fallbeispielen aus Oberschwaben. Ostfildern: Thorbecke 2009; 336 Seiten mit 85 Farb- und SW-Abbildungen, 19,80 EUR
Rezension von: Braun, Johann Wilhelm (Ed.), Das Nekrolog des Klosters Ochsenhausen von 1494
Authors: Gruber Ewald , Braun Johann Wilhelm
Published: July 2023

Das Nekrolog des Klosters Ochsenhausen von 1494. Edition: Johann Wilhelm Braun. Eingeleitet, mit Registern versehen und redigiert von Boris Bigott. Hg. von der Kommission für Geschichtliche Landeskunde in Baden-Württemberg (Reihe A, Quellen, Bd. 53 LXVI). Stuttgart: W. Kohlhammer Verlag 2010; 144 S., 13 Farbabb., Pp incl. CD-ROM 34,00 EUR
Rezension von: Martin, Jörg (Hrsg.), Erbacher Urkunden
Authors: Litz Gudrun , Martin Jörg
Published: July 2023

Erbacher Urkunden. Regesten zur Geschichte der Herrschaft Erbach und zu den Urkunden im Schlossarchiv Erbach. Bearb. von Jörg Martin, hg. von Jörg Martin, Franz Frhr. von Ulm zu Erbach, Wolfgang Schürle und Heinz Seiffert (Documenta Suevica 20). Konstanz/Eggingen: Edition Isele 2011; 887 S., 52 Abb. (sw und farbig), geb., 35,00 EUR
Rezension von: Hadry, Sarah, Neu-Ulm
Authors: Scheinhammer-Schmid Ulrich , Hadry Sarah
Published: July 2023

Sarah Hadry: Neu-Ulm. Der Altlandkreis (Historischer Atlas von Bayern. Teil Schwaben. Reihe I. Heft 18). München: Kommission für bayerische Landesgeschichte 2011; 670 S., geb., 3 Kartenbeilagen, zahlr. Abb., 37 Tabellen, 58,00 EUR
Rezension von: Knittel, Anton Philipp (Hrsg.), Unterhaltender Prediger und gelehrter Stofflieferant
Authors: Scheinhammer-Schmid Ulrich , Knittel Anton Philipp
Published: July 2023

Anton Philipp Knittel (Hg.): Unterhaltender Prediger und gelehrter Stofflieferant. Abraham a Santa Clara (1644-1709). Beiträge eines Symposions anlässlich seines 300. Todestages. Eggingen: Edition Isele 2012; 263 S., 13 Abb., brosch., 18,00 EUR
Rezension von: Rieger-Benkel, Brigitte; Dargel, Eveline; Frey, Heinrich (Hrsg.), Fritz Mauthner und Harriet Straub in Meersburg – ein ungewöhnliches Paar im Glaserhäusle
Authors: Schwarzbauer Franz , Rieger-Benkel Brigitte , Frey Heinrich , Dargel Eveline
Published: July 2023

Brigitte Rieger-Benkel/Eveline Dargel/Heinrich Frey (Hg.): Fritz Mauthner und Harriet Straub in Meersburg – ein ungewöhnliches Paar im Glaserhäusle. Tagungsbeiträge von Meersburg 2011; 96 S., 9,90 EUR
IMNU DIGITAL BOARDING SCHOOL: CAMPAIGNING DIGITAL MEDIA AND BUSINESS TO THE ISLAMIC YOUTH
Authors: Mubarok Muhamad Husni
Published: July 2023

Digital media and business are rapidly growth. IMNU has a willingness to improve digital individuals' skills. They try to campaign using social media platforms and face-to-face workshops. explore the role of IMNU in implementing strategic campaigns of digital and business media. The research is a descriptive qualitative study in which participant observation is the primary data. The result shows that IMNU campaign consists of three categories: training, tutorials, and practitioners' sharing experiences on social media. They also present face-to-face digital training or workshop in NU-based Islamic boarding schools throughout Indonesia. The existence of IMNU has become important to help Islamic youth in developing their digital skill and accompanying them to provide knowledge on digital literacy
The use of the NATEC P platform in the mathematics curricular component
Authors: Carmignolli Andreza , De Souza Lemes Sebastião , Muzzeti Luci Regina , Sanseverinato Micheleti Laís Inês , Celli de Oliveira Maria Fernanda
Published: July 2023

Through large-scale assessments, the Brazilian educational system assesses the quality of its performance through a set that allows the school, in addition to knowing the knowledge of its students, to create strategies aimed at educational development. In this sense, this study aimed to analyze the results of educational assessments, specifically with regard to Mathematics, aiming to map the difficulties of students and help teachers in the development of special strategies. This study was consolidated through action research, which aimed to analyze the data collected by the NATEC P Platform, a technological resource developed by the NATEC P research group (Center for Studies in Assessment, Technology, Curriculum and Public Policy - Study Group in Assessment, Technology, Curriculum and Public Policies) from the Faculty of Sciences and Letters of Araraquara and used by a Brazilian school, in the interior of São Paulo, belonging to the state education network, of the Board of Education of Araraquara. As a result of this research, we verified that the platform has allowed teachers to be agile in pedagogical interventions through the analysis of the results presented. Thus, we intend to bring an alternative that effectively contributes to students with learning delays, through a study that allows us to analyze the potential and restrictions that technological resources can bring to education.
Work and income: the challenge of implementing universal basic income in Brazil
Authors: Borges Lazaro , Gallo Zildo , De Lorenzo Helena
Published: July 2023

The new configuration of global economic actors and the dampening of productive activity as a result of the COVID-19 pandemic has brought ideals like Universal Basic Income (UBI) to the forefront in the search for alternatives to national development. However, UBI faces resistance as it is associated with discouraging labor activity, which would affect the proper functioning of the economy. The objective of this research was to analyze the condition of work and income in Brazil based on data obtained from the Pesquisa Nacional por Amostra de Domicílios Contínua – Divulgação Trimestral (PNADC/T), for the period 2012-2022, with the intention of delineating its current scenario and assessing whether UBI would bring about the negative impacts associated with it in the economy. The results demonstrate that the supply of work and income does not respond to job and income generation programs and tends towards precariousness and informality in the world of work, along with restricted access to income, which does not constitute an impediment to the adoption of UBI.
Partial characterization of a bacteriocin-like inhibitory substance produced by Streptococcus equinus C6I9, a bovine rumen isolate.
Authors: Magalhães Júnior Géssica Aparecida de , Fochat Romário Costa , Húngaro Humberto Moreira , Ribeiro João Batista , Lima Júnior César Fernandes , Carneiro Jailton da Costa , Vicentine Karina Ferrazzoli Devienni , Barbosa Ana Andrea Teixeira , Paiva Aline Dias
Published: July 2023

The present study aimed to evaluate the production and the factors that influence the antimicrobial activity of a bacteriocin-like inhibitory substance (BLIS) produced by Streptococcus equinus C6I9, a bovine rumen isolate. The antagonist activity was evaluated by the spot-on-lawn assay. Antimicrobial activity of the crude extracts obtained using NaCl acidic solution (pH 2, 100 mM) was evaluated along the bacterial growth and in growth medium containing different carbon and nitrogen sources, by agar diffusion method. Crude extract was evaluated regarding temperature stability, storage conditions, and pH sensitivity. S. equinus C619 inhibited both Gram-positive and Gram-negative strains. The crude extract was sensitive to proteinase K, and showed great stability to different temperatures and pH (2 to 12). The presence of meat extract (1.5 g/L) and sucrose (8 g/L) resulted in higher production of BLIS by S. equinus C6I9. The BLIS molecular mass was determined as approximately 3.5 kDa. The results obtained in this study evidenced the production of a broad spectrum activity, thermo- and pH stable BLIS by the ruminal isolate S. equinus C6I9, important features for its biotechnological application.
The Path Less Trodden
Authors: Harper Sue
Published: July 2023

This essay critically reviews my own academic career and creative practice, and argues that there can be a fruitful crossover between the methodologies of historical research and creative writing. I discuss the issue of artistic innovation and the cultural conditions most likely to foster it, analyse the notion of discursive density, and argue for the necessity of eclecticism in social and gender politics. The paper works with the themes of Adornment, Documents, Assimilations, and the Numinous, and argues for the existence of creative scholarship and grounded fiction.
Shakespeare and the Popular Film Industry
Authors: Pikli Natália
Published: July 2023

Shakespeare’s popularity on the big screen increased exponentially in the 1990s, largely thanks to Kenneth Branagh’s and Baz Luhrmann’s films and Shakespeare in Love (1998), co-written by Marc Norman and Tom Stoppard, which became the highest grossing Shakespeare film. In the recent two decades, the popular movie industry has also rediscovered the marketing value and crowd-tickling element in Shakespeare allusions, and several box office success genres, like superhero films, relied on “Easter egg” inclusion of well-known Shakespearean quotes or motifs. This paper offers a bird’s eye view of several tendencies characterising the attitude of the popular film industry to Shakespeare in the last 30 years. It also presents brief case studies with a focus on what makes or unmakes a “Shakespeare film” at the box office and in critical opinion, arguing that success relies on some form of a crossover effect. The films in focus are Baz Luhrmann’s Romeo+Juliet, Shakespeare in Love, Joss Whedon’s film noiresque, Much Ado About Nothing (2012), and Richard Eyre’s King Lear (2018).
Ned Kelly without a Beard
Authors: Gall Cecilia
Published: July 2023

Before Justin Kurzel’s 2019 adaptation of Peter Carey’s 2001 Booker Prize winning The True History of the Kelly Gang came out, almost a dozen films had already been made about the outlaw Ned Kelly. Raising money for a new film seemed like an impossible task. What untold aspects are there of this story? Kurzel, as Carey, was not interested in telling how it really was. Rather he became interested in how history can be "stolen" and turned into political agenda. The oft-told story of the Kelly Gang continues to define the way Australians think about themselves and their national identity. Kurzel’s disturbing take on Carey’s book is not likely to turn out to be a crowd pleasing, popular film. This paper aims to examine how the film deliberately breaks with the received notions of Kelly representations. A beardless Ned Kelly succeeds in alienating rather than identifying the viewer with the main character, thus highlighting the artificial character of the Ned Kelly myth.
PENGGUNAAN MEDIA LABORATORIUM VIRTUAL PADA PELATIHAN DI WILAYAH KERJA GURU IPA MTS DI KANTOR KEMENTERIAN AGAMA KABUPATEN WAYKANAN DAN KABUPATEN LAMPUNG SELATAN
Authors: Basuki Basuki
Published: July 2023

Tujuan dari penelitian ini adalah untuk mengetahui penggunaan laboratorium virtual dalam pembelajaran materi esensial IPA Fisika pada pelatihan di wilayah kerja guru IPA MTs. Subjek pada pelatihan ini adalah peserta yang mengikuti pelatihan di wilayah kerja guru IPA MTs kantor kementerian Agama Kabupaten Waykanan dan Kabupaten Lampung Selatan sebanyak 53 responden. Metode yang digunakan adalah survey. Hasil yang diperoleh 90% menyatakan laboratorium virtual dapat menambah motivasi dalam belajar, 86,79% memudahkan dalam memahami materi fisika, 84,43% kemampuan berpikir lebih berkembang, 91,50% senang memanfaatkan laboratorium virtual, 93,86% menarik untuk proses pembelajaran, 74,05% menyatakan pembelajaran yang baru baru, 89,62% mengembangkan kemampuan bernalar, 88,20% menyatakan pembelajaran lebih efektif. penggunaan media pembelajaran berbasis laboratorium virtual berbantuan PhET dapat memberikan kontribusi dan selanjutnya media pembelajaran ini dapat memberikan jawaban yang bagus untuk pembelajaran di PDWK Guru IPA MTs di Kantor Kementerian Agama Kabupaten Waykanan dan Kabupaten Lampung Selatan.
EFEKTIVITAS PELATIHAN KONSELING SEBAYA PADA SISWA SMK NEGERI 5 MAKASSAR
Authors: Nisa Cinta Khoirina , Ilahi Muh. Ilham Nur , AR Nurul Fitriah , Aknis Ravael Jehuda , Permadi Rahmat
Published: July 2023

Konseling adalah sebuah kegiatan yang terdapat hubungan timbal balik antara dua orang individu, dimana konselorakan berusaha membantu yang lain (konseli) agar dapat memahami tentang dirinya sendiri dalam menghadapimasalah-masalah pada waktu yang akan datang. Konseling sebaya dianggap penting dikarenakan remaja lebih sering menceritakan masalah yang tengah dihadapinya ke teman sebaya dibandingkan dengan orang tuanya maupun guru disekolah. Sebagai bentuk kontribusi peneliti, membuat program terkait “ Efektifitas Pelatihan KonselingSebaya”. Partisipan penelitian ini adalah siswa SMK Negeri 5 Makassar yang tergabung dalam organisasi PIK-R. Hasil penelitian menunjukkan bahwa terdapat peningkatan skill partisipan untuk menjadi konselor bagi teman sebayamereka.
Intoxicación fatal con paraquat por vía dérmica. Reporte de caso
Authors: Lanza Suyen
Published: July 2023

Introducción: Por su alta letalidad el paraquat es utilizado con fines suicidas, siendo la principal vía de uso, la oral, los casos por vía cutánea son escasos y raras veces son fatales, este reporte presenta un caso de compromiso sistémico severo y muerte después de exposición dérmica a paraquat. Resumen del caso:Paciente femenina de 47 años, soltera, ama de casa, de procedencia rural y secundaria incompleta; con historia de aplicación de paraquat en ulcera, a las 24h de aplicación presento fiebre, vómito y malestar general; al ingreso hospitalario presento además ictericia generalizada, insuficiencia renal aguda, insuficiencia respiratoria, deterioro progresivo de su estado de salud y muerte, por lo que fue remitida a autopsia médico legal. Los hallazgos de autopsia descartaron la ingesta oral y mostraron páncreas hemorrágico, riñones congestivos, hígado de tamaño aumentado (2550g) y hemorrágico, corazón aumentado de tamaño. Los estudios histopatológicos mostraron daño alveolar difuso, (membranas hialinas, edema y hemorragia); neumonía en pulmón y congestión visceral generalizada. Conclusión:El caso reportado no solo es relevante porque informa de una vía inusual de intoxicación por paraquat como es la dérmica, sino porque expone dos problemas coadyuvantes para que las intoxicaciones por plaguicidas ocurran: “la fácil disponibilidad y el desconocimiento de uso, manejo y efectos de estos”.
The role of gold nanoparticles in anticancer activity
Authors: Murtadha M-Hussein A-Kadhim  , Ameer Jawad hadi  , Siham Adnan Abdulsada
Published: July 2023

To enhance the cellular uptake and chemotherapeutic efficacy of a current chemotherapeutic medication, a nanoparticle drug carrier technology has been designed. Due to their distinctive electrical and optical characteristics, gold nanoparticles (Au NPs) have recently demonstrated intriguing medical and military uses. In the event that they come into touch with a biological system, little is known about their biocompatibility. Metallic nanoparticles have been successfully utilized for a kind of biological applications. A drug delivery system known as Au – PEG – PAMAM – DOX was produced by conjugating the dendrimer with the anti-cancer chemical doxorubicin (DOX) via an amide bond. The amount of DOX released from Au – PEG – PAMAM – DOX at a natural pH was negligible, but this amount significantly increased in an environment with a weak acidic milieu, according to studies on the release of medicines from acellular sources. A research into the intracellular release of the medication was carried out with the assistance of confocal laser scanning microscopy (CLSM). Recently conjugation to the nanosystem, In vitro viability experiments revealed an increase in the associated DOX cytotoxicity that could not be attributable to carrier components. This indicates that the effectiveness of the DOX was increased. In light of this, it has been hypothesized that the newly created pH-triggered multifunctional Au NPs- DOX nanoparticle system could pave the way for a viable platform for the intracellular delivery of a range of anticancer medicines. In the current study, the common Au NPs synthesis techniques and their well-established uses in diverse needs, particularly in biological sensing applications.
Qualitative story completion: A creative and novel method for psychotherapy and counselling psychology research
Authors: Clarke Victoria , Moller Naomi
Published: July 2023

Story completion (SC) – where respondents are presented with the start of a story (the story ‘stem’ or ‘cue’) and asked to complete it – originally developed as a projective technique for clinical and research assessment. While SC continues to be used in this way, it has also evolved into a qualitative data generation technique, providing qualitative researchers with a creative and novel alternative to the self-report data typical of qualitative research. In this paper, we outline the growing interest in the method within psychotherapy and counselling psychology research and explain what we think the method offers to this field of research. To support psychotherapists and counselling psychologists in adding SC to their methodological toolkit, we also provide practical guidance on the design and implementation of SC, drawing on an example study exploring perceptions of ethnic/racial differences between a therapist and client.
Digital storytelling: A proposed creative therapeutic intervention for bereaved families
Authors: Pakandlova Adela
Published: July 2023

Digital storytelling is a qualitative visual research method that is becoming increasingly popular. It is based on collaboratively creating short digital movies conveying participants’ stories which can also be presented to the public, and represents not only a research method but also a beneficial therapeutic tool for both adults and children. Within the context of psychotherapy, digital storytelling has helped individuals to connect not only at an intrapersonal level, but also at an interpersonal level, and has been a valuable part of the healing process. Based on these promising findings, this article presents a proposed creative intervention for bereaved families based on digital storytelling together with a dance-movement activity. The steps are outlined, and the goal of this intervention is to help the bereaved to build resilience, to process their grief and to heal together as a community. The implications for practice are then discussed.
Penyuluhan dan Pelatihan Pembuatan UMB (Urea Molasses Block) Pada Peternak Sapi Potong di Desa Blengorwetan, Kecamatan Ambal, Kabupaten Kebumen
Authors: Chalisty Vian Dwi , Priyono Eko , Soleh Ibnu , Nuryani Nuryani , Aminah Siti , Rinjani Rinjani , Aini Siti Nur , Maskuroh Siti , Kusmiati Lili , Istinganatun Holisoh
Published: July 2023

Blengorwetan Village, Ambal District, Kebumen Regency is an area with the potential for developing Kebumen PO cattle farms, but has problems in terms of fulfilling animal feed nutrients. The majority of farmers provide feed in the form of dry rice straw, which is low in protein, vitamins, and minerals, and high in crude fiber. Based on these problems, this community service activity aims to provide counseling and training on the manufacture of Urea Molasses Block (UMB) to farmers. Urea Molasses Block (UMB) is an animal feed supplement that serves to improve the nutritional value of animal feed; digestion and digestibility of animal feed substances will be more efficient and improved; consumption of ruminant feed will increase, and avoid vitamin and mineral deficiencies. The methods used include field surveys, discussions with village officials, socialization to increase the knowledge of farmers about UMB, and training in making UMB which is followed in a participatory manner by the community. Trials of giving UMB to livestock by the community show UMB is favored by livestock and can increase animal feed consumption. Based on the activities that have been carried out, it can be concluded several things, namely (1) the training on making UMB has been successfully implemented with indicators of understanding and skills of cattle farmers increasing regarding UMB products and how to manufacture them, (2) UMB products produced are of sufficient quality and favored by livestock. , (3) further breeders wish to make UMB products independently for consumption by their own livestock, with the hope of increasing livestock productivity.
Keywords: Urea Molasses Block, Livestock, Feed Supplement
Pelatihan Strategi Penulisan Artikel Ilmiah untuk Publikasi di Jurnal Internasional Bereputasi Tinggi bagi Periset BRIN
Authors: Pamungkas Onok Yayang
Published: July 2023

The problem that underlies this PkM activity is the lack of optimal competence of BRIN researchers in writing scientific articles for publication in reputable international journals. For this reason, this PkM activity aims to provide training on strategies for writing scientific articles for publication in reputable international journals. The method used is in the form of training and mentoring for BRIN researchers. The training is carried out online (online) through the zoom application, while discussions and consultations (assistance) are also carried out online through the Whatsapp application. This activity is carried out in four stages, including; preparation stage, implementation stage, discussion and consultation stage, and evaluation stage. Based on the results and discussion, it is shown that the trainees still experience problems in publishing scientific articles. Based on discussions and consultations, participants have high enthusiasm to be able to carry out quality research and publish in reputable international journals. Through this PkM activity, it is hoped that it will increase the capacity of BRIN researchers in writing quality scientific articles for international publications..
Keywords: publication strategy, scientific articles, community service
Pengaruh Interval Ekstensif dan Fartlek Terhadap Kapasitas Vo2maks Pemain Futsal MUTU FA Kebumen
Authors: Syarif Ahmad , Erfayliana Yudesta , Utomo Andy Widhiya Bayu , Sumantri Riyan Jaya , Mudayat Mudayat , Widiyono Ibnu Prasetyo , Yogi Ferdy Irawan Yogi Ferdy Irawan , Muhafid Ervian Arif
Published: July 2023

Based on the author's observations in the field, it shows that the VO2max capacity of the MUTU FA Kebumen futsal players is still low. This is possible due to the lack of precise training methods used by trainers in the training process. This study aims to see the effect of extensive interval training and fartlek training on the VO2max capacity of MUTU FA Kebumen futsal players. This research method is a quasi-experimental method (quasi experimental). The population of this study was 30 people, while the sample was taken by purposive sampling so that a sample of 24 players was obtained. The test used is the bleep test which aims to determine the VO2max capacity of futsal players. The results of the data analysis show that: 1) extensive interval method training has a significant effect on the VO2max capacity of MUTU FA Kebumen futsal players; 2) fartlek training has a significant effect on the VO2max capacity of MUTU FA Kebumen futsal players; 3) extensive interval method training provides a more effective effect than fartlek training on increasing the VO2max capacity of MUTU FA Kebumen futsal players.Keywords: Exercise, VO2max, Futsal
Sustainable Marketing Strategies: A study on the Effectiveness of Green Marketing Initiatives in Promoting Sustainable Consumption
Authors: Vaja Jignesh R. , Raval Zankhit Yashvantbhai
Published: July 2023

The purpose of this research is to analyse the efficacy of green marketing activities in encouraging sustainable consumption and to investigate sustainable marketing methods. Businesses are beginning to include "green marketing" activities into their overall marketing strategy in order to attract customers who are environmentally sensitive as sustainability becomes an increasingly significant factor in consumer decision-making. The purpose of this research is to evaluate the influence that these activities have had on the behaviour of consumers and to establish the degree to which different sustainable marketing methods are successful. The investigation will make use of a variety of research approaches, including qualitative and quantitative approaches, such as questionnaires, interviews, and examinations of various advertising campaigns. The outcomes of this research will contribute to a greater understanding of the role that green marketing plays in encouraging sustainable consumption and will give companies with insights that will help them design successful sustainable marketing strategies.
ADALET YÖNETİMİNDE ETKİNLİK ARAYIŞLARI: ROBOTİK BÜROKRASİ VE YAPAY ZEKÂ YÖNETİŞİMİ
Authors: ÖZER Mehmet Akif
Published: July 2023

Bu çalışmada sorunları çözmekte zorlanan bürokrasinin çıkış arama sürecinde dijitalleşmesi ve teknolojiden yararlanması sürecinde yapay zeka yönetişimi uygulamalarından ve robotik bürokrasinden nasıl yararlanabileceği hususu adalet yönetimi özelinde incelenmektedir. Dünya genelinde adalet yönetiminde yaşanan sorunlar analiz edildiğinde bilgi iletişim teknolojilerinin yetersiz kullanılmasının temel rol oynadığı çok açıktır. Bu nedenle yönetimde robotlaşma ve yapay zeka uygulamaları büyük adalet yönetimi alanında büyük önem taşımaktadır. Bu kapsamda çalışmada önce bürokrasinin neden yıprandığı ve sorunlara çözüm bulamadığı, adalet yönetimin bürokratik çıkmazları özelinde incelenmiştir. Ardından bu alanda yaşanan teknolojik gelişmelerin, verimlilik arayışlarına katkısı değerlendirilmiştir. Dijital teknolojilerin kullanımını içeren dijital otomasyonun önemli bir bileşeni olan robotik süreç otomasyonu ve robotik bürokrasi konusu ele alınmış, buradan teknolojik adalet yönetimi ve yapay zekâ yönetişimi uygulamalarına geçilerek, adalet yönetiminin bu süreçten nasıl etkilenebileceği değerlendirilmiştir. Sonuçta etkin ve verimli bir adalet yönetimi için teknolojiden mutlak surette yararlanılması gerektiğine, bu doğrultuda robotik bürokrasinin ve yapay zeka uygulamalarının sürece çok ciddi katkısı olacağı gerçeğine ulaşılmıştır.
A Survey of Forecasting the Salary for Players in National Basketball Association
Authors: Chen Xingsi , Lin Haoyang , Pang Louyang , Wang Yanxiang
Published: July 2023

The National Basketball Association is the men's professional basketball league in North America. The National Basketball Association league has some of the highest paid professional athletes in the world. The National Basketball Association is the oldest and most prestigious basketball league in the world, which makes the study of the NBA particularly important. During the 2011-2012 season, the season was cancelled after senior staff and team members failed to reach an agreement due to serious differences of opinion in labour management negotiations. The main reason was that the NBA believed that the players' salaries were too high, which left little profit for the NBA and even increased the NBA's losses. Since the ideal interests of management and the interests of labor did not exactly match, both sides made concessions and reached an agreement. Finally, the season resumed. For most NBA clubs, the salary of each player is usually confirmed before the performance in the next game. However, this makes the question of how to determine the amount more difficult. Players’ salaries should match their performance. If the player does not meet salary expectations, the club is losing money. If a player finds that he gets paid less than his income based on 61 games that year, the club may lose that player and reputation. In this paper, we summarize previous approaches for salary forecasting and categorize them into: (i) linear regression, (ii) modelling approach, and (iii) non-linear regression and (iv) K-nearest neighbour classifier and provide guiding idea for future work.
Analysis of Regional Differences, Dynamic Evolution and Convergence Characteristics of The Level of Rural Revitalization in China
Authors: Li Wenqing , Zhou Xiaoxiao , Ding Zhongming
Published: July 2023

To help rural revitalization, it is extremely important to understand the inter-provincial characteristics. This paper uses the entropy value method to measure the comprehensive index of rural revitalization level, and reveals the regional differences and dynamic evolution trend of rural revitalization with the help of Dagum Gini coefficient and kernel density method, and finally uses the  convergence model to test the spatial and temporal convergence. The study finds that the level of rural revitalization is low but tends to increase year by year. Regional differences are the main reason for the differences in rural revitalization, but they are decreasing. There is a polarization phenomenon of inter-provincial rural revitalization level, while there is a tendency for low-level provinces to catch up with high-level provinces. Finally, it is suggested that all kinds of factors should be fully activated to actively promote the coordinated development of regional rural revitalization level.
Research on the Impact Mechanism of Economic Policy Uncertainty on Bitcoin Prices
Authors: Zhu Minghui
Published: July 2023

Has there been a linkage mechanism between the prices of Bitcoin and traditional wealth preservation investment tools, that is, Bitcoin may serve as an investment substitute when other investment tool markets are sluggish, or can also benefit from it when the overall investment market is hot. The price of Bitcoin exhibits extremely unstable characteristics, as it can double its value dozens of times in a very short period of time or return to its starting point in a single day. The rapid rise and short duration of Bitcoin's price show us its infinite potential. Through research, this paper finds that the price of Bitcoin fluctuates greatly, while the U.S. Dollar Index and the S&P 500 index are basically horizontal, and their volatility is relatively small. Therefore, Bitcoin may be used as a speculative product, and there is a lot of speculative behavior in the market. When the investment attributes of Bitcoin dominate, an increase in economic policy uncertainty will significantly suppress investor sentiment and cause Bitcoin prices to decline. In addition, its impact on the world financial system is also increasing.