bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Profitability, Institutional Ownership on Tax Avoidance Moderated by Disclosure of Good Corporate Governance (Study on Consumer Goods Industry Companies Listed in the Indonesia Stock Exchange in 2016 – 2020)
Authors: Muhammad Evdi , Efni Yulia , Rahmayanti Elvi
Published: July 2022

This study aims to analyze the effect of profitability, institutional ownership on tax avoidance moderated by disclosure of good corporate governance. This study uses 24 consumer goods industrial sector companies listed on the Indonesia Stock Exchange during the 2016-2020 period as research samples. The data is collected based on the annual report as well as the company's financial statements. Partial Least Square (PLS) is used as a method to analyze the data that has been obtained. The results showed that profitability had a significant negative effect on tax avoidance. Institutional ownership has no significant effect on tax avoidance. For testing the moderating variable, it is proven that the disclosure of good corporate governance is able to moderate the relationship between profitability and tax avoidance, but the disclosure of good corporate governance is not able to moderate the relationship between institutional ownership and tax avoidance.
Angielsko-polski słownik IA, UX, UI & SEO
Authors: Tomaszczyk Jacek , Matysek Anna
Published: July 2022

Angielsko-polski słownik IA, UX, UI & SEO to pierwsze w Polsce opracowanie słownikowe tematyki z zakresu architektury informacji, wrażeń i interfejsów użytkownika oraz badań użyteczności i optymalizacji serwisów internetowych. Tak licznego i uporządkowanego zbioru słownictwa tej branży nie znajdziemy nawet w światowych zasobach terminologicznych. Autorzy zgromadzili kolekcję ok. 4800 terminów i wyrażeń specjalistycznych, którym przypisali polskie odpowiedniki, a często także objaśnienia, dopowiedzenia i odsyłacze. Do wszystkich wyrazów hasłowych podano wymowę reprezentowaną za pomocą International Phonetic Alphabet. Adresatem słownika są przede wszystkim studenci kierunku architektura informacji oraz projektowanie przestrzeni informacyjnych. Słownik powinien także znaleźć liczne grono odbiorców wśród osób zainteresowanych projektowaniem serwisów internetowych oraz tworzeniem i marketingiem produktów i usług cyfrowych.
Zróżnicowanie roślinności łąkowej i ziołoroślowej Doliny Górnej Wisły i jej znaczenie w ochronie przyrody
Authors: Wilczek Zbigniew , Michniok Justyna , Zarzycka Magdalena , Zarzycki Wojciech
Published: July 2022

The book presents the characteristics of meadow and herb plants occurring in the Upper Vistula Valley. The significance of the vegetation in nature protection has been determined by the assessment of the share of protected vascular plant species and alien plant species which pose a threat to the phytocoenoses under investigation. Plant communities have been identified as Natura 2000 natural habitats and it has been proposed to create new protected areas to preserve the best-developed patches of vegetation studied.
The features of diagnostics of grain crop seeds intended for export
Authors: Ruchkov E. R. , Shukhin D. I. , Kuznetsova A. A. , Kopina M. B.
Published: July 2022

Russia occupies a leading position among the largest wheat producers and exporters. One of the key requirements for the biological safety of domestic grain products is the phytosanitary requirements of importing countries. The conformity of grain products with regard to phytopathogenic micromycetes is determined by their complete absence or the minimum content in the batch. When shipping exported products, it is necessary to carry out a phytosanitary estimation of a batch of plant products in a short time. In the current paper there has been estimated the effect of the proposed method of sample preparation of grain crop seeds on the quality of an isolated fungal pathogens’ DNA. The purpose of the study was to optimize the methods of sample preparation of grain products for the extraction of nucleic acids with further identification to reduce laboratory trials. The development of modern, reliable and low labor-consuming methods for diagnosing phytopathogens in plant products is of great urgency. In order to conduct the current research, wheat, barley and rye kernels were artificially inoculated with such fungal pathogens as Parastagonospora nodorum, the causative agent of Septoria leaf spot, and Alternaria infectoria, the causative agent of Alternaria leaf spot. The infection was carried out by soaking the kernels in a spore suspension followed by incubation. In order to assess infection, there were used the classical methods of mycology, as well as the patented E.Yu. Toropova’s method. The pathogens were identified by a classical PCR analysis using the target-specific primers. There has been given an assessment of the sensitivity of the proposed extraction method for each of the studied crops. The method allows identifying target objects even with a minimum number of infected kernels in the sample (1–5 infected seeds per 195–199 healthy ones). There were not identified any related pathogens, and there were no false-positive results during the conducted PCR analysis.
Effectiveness of Early Postpartum Rectus Abdominis versus Transversus Abdominis Training in Patients with Diastasis of the Rectus Abdominis Muscles: A Pilot Randomized Controlled Trial
Authors: Simpson Eloise , Hahne Andrew
Published: July 2022

Purpose: To determine feasibility of a randomized controlled trial (RCT) comparing postpartum rectus abdominis training with transversus abdominis training in reducing the inter-recti distance in patients with diastasis of the rectus abdominis muscles (DRAM). Method: A pilot, randomized controlled trial with longitudinal assessment following vaginal delivery at 6 and 12 weeks postpartum was completed. Forty-four women with DRAM (inter-recti distance of ≥ 30mm as measured by digital calipers) were recruited from a regional public hospital in Australia. The standard treatment group ( n = 21) was provided with a 5-second transversus abdominis activation exercise in crook lying. The experimental group ( n = 23) was provided with a 1-second rectus abdominis crunch exercise. Dosage was between 1–10 repetitions at baseline and between 1–20 at 6 weeks, twice a day, at least 5 days per week, prescribed depending on individual participant ability. The primary outcome measure was inter-recti distance. Feasibility measures were recruitment rate, loss to follow-up, adverse events, and exercise adherence. Results: The rectus abdominis group achieved greater reduction of the inter-recti distance at 6 weeks (at and below the umbilicus) and 12 weeks (above, below, and at the umbilicus). Recruitment rate was acceptable (45%) and there were no adverse events, but loss to follow-up was high due to COVID-19 impacts and participants did not return exercise adherence diaries. Conclusion: Prescription of rectus abdominis exercise during the early postpartum period following vaginal delivery resulted in a greater reduction of the inter-recti distance at 6 and 12 weeks when compared with transversus abdominis exercise. This pilot trial was impacted by high loss to follow up due to COVID-19 restrictions, but feasibility was otherwise acceptable. The findings of the study will inform future fully powered trials comparing these two exercise types in postpartum women with DRAM.
Measuring Perceived Tourism Service Quality in Quantitative Marketing Research
Authors:   University of Novi Sad, Faculty of Economics in Subotica, 9-11 Segedinski put, 24000 Subotica, Republic of Serbia, Djokic Ines , Milicevic Nikola ,   University of Novi Sad, Faculty of Economics in Subotica, 9-11 Segedinski put, 24000 Subotica, Republic of Serbia, Djokic Nenad ,   University of Novi Sad, Faculty of Economics in Subotica, 9-11 Segedinski put, 24000 Subotica, Republic of Serbia
Published: July 2022

The need to measure service quality in the tourism industry is present for decades. During that period many different instruments designed to perform that measurement were developed. However, the analysis performed when using those instruments relatively rarely relies on scientific contributions by which service quality should be treated as reflective-formative constructs. Such misspecifications can lead to serious mistakes in the results and can raise doubts about implications from studies that do not consider service quality appropriately. Having all previously stated in mind, this paper has three main objectives. The first objective is to present instruments designed to measure perceived tourism service quality in one place. The second goal is to demonstrate the view of perceived service quality as second order formative-reflective construct. Finally, the third objective is to present simulation of differences in the results when treating perceived service quality as reflective-reflective and as a reflective-formative construct.
Film Industry in the Function of Destination Branding
Authors:   Faculty of Law, Security and Management “Constantine the Great” Nis, Dašić Dejan ,   Faculty of Sports Belgrade, University Union – „Nikola Tesla” Belgrade, Serbia, Kostadinović Gruja ,   Faculty of Law, Security and Management “Constantine the Great” Nis, University Union – „Nikola Tesla” Belgrade, Serbia
Published: July 2022

The subject of this paper is the influence of the film industry on destination branding, where we imply the creation of a positive image and economic aspect. The paper points out the growing influence of the film industry as an attractive marketing tool, which increases the recognizability and image of the destination, which results in a significant increase in the number of tourists. Film tourism offers destinations the opportunity to generate significant incremental revenues, tourist visits and economic development, thriving where traditional marketing efforts cannot or yield poor results.
What We Can Learn from the Process of Urbanization of a Mountain Tourist Resort: The Zlatibor Case
Authors:   University of Belgrade, Faculty of Economics, Kamenička 6, Belgrade, Serbia, Filipović Milorad , Hadžić Miroljub ,   University Singidunum Belgrade, Faculty of Business, Danijelova 29, Belgrade, Serbia, Vujošević Miodrag ,   Institute of Urbanism and Spatial Planning RS, Bulevar kralja Aleksandra, Belgrade, Serbia
Published: July 2022

Serbia started the transition in 2000 using a neoliberal development approach. Since 2012, a populist model of development has been underway. In such an environment the mountain tourist resort of Zlatibor became an example of an inadequate decision-making process, with inevitable negative long-term outcomes. Speeding up in reforming construction permits, unfortunately, made room for too fast urbanization of Zlatibor. Granting construction permits on the local level, without a comprehensive development plan of the destination as a broaden development frame, was a wrong reforming step. It is complicated by political fighting between the top (Republican) level and local level of governing, regarding interests. An additional problem is related to the wrong defined place for decision – making process. Namely, Zlatibor became too large and too rich for its local capital, Čajetina. The aim of the paper is firstly, to envisage development problems of Zlatibor, potentially “Mountain Kaludjerica”, like ecological, infrastructure and touristic disaster, if rapid, chaotic urbanization continues, and secondly, to point out some institutional, decision making and practical steps toward neutralization of these negative outcomes.
CO2 Neutrality of Small and Medium-Sized Hotels – Publicity Stunt or Sustainable Competitive Advantage?
Authors:   Faculty of Economics, University of South Bohemia, Studentská 13, 370 05 České Budějovice, Czech Republic, Enz Christian , Škodová Parmová Dagmar ,   Faculty of Economics, University of South Bohemia, Studentská 13, 370 05 České Budějovice, Czech Republic, Wolf Paul ,   Mathematics and Statistics, University of Stralsund, Zur Schwedenschanze 15, 18435 Stralsund, Germany
Published: July 2022

The topic of climate protection is steadily gaining importance in public discussion. This paper shows that CO2 emissions are also gaining significant influence on booking behaviour in tourism. At the same time, it can be demonstrated in the context of a large-scale survey that with a growing desire for CO2 neutrality, higher accommodation rates are also accepted. Large hotel chains already regularly have integrated sustainable thinking into their daily routine. SMEs currently have some catching up to do. While hotel groups are accused of greenwashing, SMEs can generate a competitive advantage through individual, traceable measures.
The Impact of The Immune Check Point Duration of use on Cost in Lung Cancer
Authors: M. Guirgis Helmy
Published: July 2022

Background: Monotherapy and combinations of Pembrolizumab (Pembro), Atezolizumab (Atezo) and Cemiplimab (Cemi), prolonged overall survival (OS) in advanced/metastatic non-small cell lung cancer (a/m NSCLC). Pembro demonstrated 5-year OS gain. The duration of therapy of the immune check point inhibitors (ICI) has not been defined. One-year adjuvant Durvalumab (Durv) and Atezo significantly prolonged OS. Neoadjuvant few cycles resulted in positive outcomes. Costs are relatively expensive, multiplying with prolonged use. The estimated 2019 CAR-T cost was $450,000. The Affordable Insulin bill 6833 capping insulin monthly cost at $35 was approved by the U.S. House of Representative. There are unmet needs for coherent drug cost policies and containment. We aimed 1- Explore the factors which impact ICI costs in lung cancer stages 2- Navigate cost-saving strategy based on generics, therapy duration and monotherapy utilization thresholds at $450,000 and $550,000 for combinations Methods: Clinical studies outcomes were quoted. Annual drug prices were calculated. Results: Estimated annual Pemetrexed (Peme) costs were $113,793, generic chemicals < $1,000 and Bevacizumab (Bev) $150,126 vs $148,000, mean 6 ICI. Pembro 2-year costs were $334,652. The 3- $501,978 and 5- $836,630 were above the $450,000. Atezo + Bev+ Peme combination had the highest 2-year $722,977 costs, above $550,000. Atezo + Peme costs were $422,725, Pembro + Peme $448,445 and Cemi + Peme $425,385, not significantly different. Costs decreased by 25% using generics. Extending ICI use by 6-12 months increased combination costs by 25-50%. Adjuvant 1-year Durv costs were $148,013 and Atezo $154,446, half the 2-year. Using response rates, cost of neoadjuvant Nivolumab (Nivo) 2-4 cycles were $25,000 - $50,000. Conclusion: Generics, short ICI duration use, neo-adjuvants, and utilization thresholds reduced costs.
Analisa Penjadwalan Produksi Emergency Air Reciever dengan Menggunakan Master Production Schedule di PT. Boma Bisma Indra
Authors: Assaabiq Muchammad , Yuniawati Ratna Diah
Published: July 2022

PT Boma Bisma Indra (Persero) is a State-Owned Enterprise (BUMN) which has 3 divisional business units, one of which is the industrial machinery and equipment division (MPI) and the foundry unit located on Jl. Imam Bonjol No. 18 Bugul Lor, Pasuruan City, East Java. The industrial machinery and equipment division and foundry unit (MPI) located in Pasuruan has grown rapidly as a company that focuses on manufacturing machinery and produces products such as Oil & Gas/ Refinery / Petrochemical Industries, Power plans, Iron Casting, and Pressure Vessels. In PT. Boma Bisma Indra, whose orientation is a make-to-order company, where the new company will procure raw materials and run production if there is a request from the customer. Difficulties that are often encountered in make-to-order companies are delays in the arrival of raw materials, and process delays caused by inadequate workers. Therefore, a method called the Master Production Schedule (MPS) is needed where this method will determine the time period that will be required for each process starting from the preparation of documents related to procedures and product specifications to the finishing fabrication process. This research focuses on timeliness analysis in every process in the master production schedule using the master production schedule (MPS) method.
Modern intracranial electroencephalography for epilepsy localization with combined subdural grid and depth electrodes with low and improved hemorrhagic complication rates
Authors: Lee Anthony T. , Nichols Noah M. , Speidel Benjamin A. , Fan Joline M. , Cajigas Iahn , Knowlton Robert C. , Chang Edward F.
Published: July 2022

OBJECTIVE

Recent trends have moved from subdural grid electrocorticography (ECoG) recordings toward stereo-electroencephalography (SEEG) depth electrodes for intracranial localization of seizures, in part because of perceived morbidity from subdural grid and strip electrodes. For invasive epilepsy monitoring, the authors describe the outcomes of a hybrid approach, whereby patients receive a combination of subdural grids, strips, and frameless stereotactic depth electrode implantations through a craniotomy. Evolution of surgical techniques was employed to reduce complications. In this study, the authors review the surgical hemorrhage and functional outcomes of this hybrid approach.

METHODS

A retrospective review was performed of consecutive patients who underwent hybrid implantation from July 2012 to May 2022 at an academic epilepsy center by a single surgeon. Outcomes included hemorrhagic and nonhemorrhagic complications, neurological deficits, length of monitoring, and number of electrodes.

RESULTS

A total of 137 consecutive procedures were performed; 113 procedures included both subdural and depth electrodes. The number of depth electrodes and electrode contacts did not increase the risk of hemorrhage. A mean of 1.9 ± 0.8 grid, 4.9 ± 2.1 strip, and 3.0 ± 1.9 depth electrodes were implanted, for a mean of 125.1 ± 32 electrode contacts per patient. The overall incidence of hematomas over the study period was 5.1% (7 patients) and decreased significantly with experience and the introduction of new surgical techniques. The incidence of hematomas in the last 4 years of the study period was 0% (55 patients). Symptomatic hematomas were all delayed and extra-axial. These patients required surgical evacuation, and there were no cases of hematoma recurrence. All neurological deficits related to hematomas were temporary and were resolved at hospital discharge. There were 2 nonhemorrhagic complications. The mean duration of monitoring was 7.3 ± 3.2 days. Seizures were localized in 95% of patients, with 77% of patients eventually undergoing resection and 17% undergoing responsive neurostimulation device implantation.

CONCLUSIONS

In the authors’ institutional experience, craniotomy-based subdural and depth electrode implantation was associated with low hemorrhage rates and no permanent morbidity. The rate of hemorrhage can be nearly eliminated with surgical experience and specific techniques. The decision to use subdural electrodes or SEEG should be tailored to the patient’s unique pathology and surgeon experience.
Words matter: using natural language processing to predict neurosurgical residency match outcomes
Authors: Ortiz Alexander V. , Feldman Michael J. , Yengo-Kahn Aaron M. , Roth Steven G. , Dambrino Robert J. , Chitale Rohan V. , Chambless Lola B.
Published: July 2022

OBJECTIVE

Narrative letters of recommendation (NLORs) are considered by neurosurgical program directors to be among the most important parts of the residency application. However, the utility of these NLORs in predicting match outcomes compared to objective measures has not been determined. In this study, the authors compare the performance of machine learning models trained on applicant NLORs and demographic data to predict match outcomes and investigate whether narrative language is predictive of standardized letter of recommendation (SLOR) rankings.

METHODS

This study analyzed 1498 NLORs from 391 applications submitted to a single neurosurgery residency program over the 2020–2021 cycle. Applicant demographics and match outcomes were extracted from Electronic Residency Application Service applications and training program websites. Logistic regression models using least absolute shrinkage and selection operator were trained to predict match outcomes using applicant NLOR text and demographics. Another model was trained on NLOR text to predict SLOR rankings. Model performance was estimated using area under the curve (AUC).

RESULTS

Both the NLOR and demographics models were able to discriminate similarly between match outcomes (AUCs 0.75 and 0.80; p = 0.13). Words including “outstanding,” “seamlessly,” and “AOA” (Alpha Omega Alpha) were predictive of match success. This model was able to predict SLORs ranked in the top 5%. Words including “highest,” “outstanding,” and “best” were predictive of the top 5% SLORs.

CONCLUSIONS

NLORs and demographic data similarly discriminate whether applicants will or will not match into a neurosurgical residency program. However, NLORs potentially provide further insight regarding applicant fit. Because words used in NLORs are predictive of both match outcomes and SLOR rankings, continuing to include narrative evaluations may be invaluable to the match process.
Adjuvant oral tranexamic acid and reoperation after burr hole surgery in patients with chronic subdural hematoma: propensity score–matched analysis using a nationwide inpatient database
Authors: Shibahashi Keita , Ohbe Hiroyuki , Yasunaga Hideo
Published: July 2022

OBJECTIVE

Adjuvant medical treatment to reduce the recurrence rate after burr hole surgery for chronic subdural hematoma (CSDH) has not yet been established. This study aimed to investigate the association between tranexamic acid (TXA) use after burr hole surgery and the reoperation rate in patients with CSDH.

METHODS

This observational study used the Japanese Diagnostic Procedure Combination inpatient database, a nationwide inpatient database in Japan, from July 1, 2010, to March 31, 2019. The authors identified patients who were hospitalized for CSDH and underwent burr hole surgery within 2 days of admission. The primary outcome measure was reoperation within 1 year after surgery. One-to-one propensity score–matched analysis was performed to compare the outcomes between patients who started oral TXA within 2 days after surgery (TXA users) and those who did not (TXA nonusers). Robustness of the analyses was assessed using the instrumental variable analysis.

RESULTS

Of the 149,543 patients with CSDH treated at 1100 hospitals, 7366 (4.9%) were TXA users. Propensity score matching created 6564 matched pairs with highly balanced baseline characteristics. The reoperation rate was significantly lower in TXA users than in nonusers (1.9% vs 6.1%, p < 0.001) with a risk difference of −4.1% (95% CI −4.8% to −3.4%). There was no significant difference in composite adverse events (0.6% vs 0.5%, p = 0.817). Total hospitalization costs were also significantly lower in TXA users than in nonusers ($5229 vs $5344 [USD], p < 0.001). The results of the instrumental variable analysis were consistent with those of the propensity score–matched analysis.

CONCLUSIONS

Findings of this study, using a nationwide inpatient database, suggest that adjuvant TXA use after burr hole surgery was associated with a reduced reoperation rate in patients with CSDH.
Intraoperative confocal laser endomicroscopy: prospective in vivo feasibility study of a clinical-grade system for brain tumors
Authors: Abramov Irakliy , Park Marian T. , Belykh Evgenii , Dru Alexander B. , Xu Yuan , Gooldy Timothy C. , Scherschinski Lea , Farber S. Harrison , Little Andrew S. , Porter Randall W. , Smith Kris A. , Lawton Michael T. , Eschbacher Jennifer M. , Preul Mark C.
Published: July 2022

OBJECTIVE

The authors evaluated the feasibility of using the first clinical-grade confocal laser endomicroscopy (CLE) system using fluorescein sodium for intraoperative in vivo imaging of brain tumors.

METHODS

A CLE system cleared by the FDA was used in 30 prospectively enrolled patients with 31 brain tumors (13 gliomas, 5 meningiomas, 6 other primary tumors, 3 metastases, and 4 reactive brain tissue). A neuropathologist classified CLE images as interpretable or noninterpretable. Images were compared with corresponding frozen and permanent histology sections, with image correlation to biopsy location using neuronavigation. The specificities and sensitivities of CLE images and frozen sections were calculated using permanent histological sections as the standard for comparison. A recently developed surgical telepathology software platform was used in 11 cases to provide real-time intraoperative consultation with a neuropathologist.

RESULTS

Overall, 10,713 CLE images from 335 regions of interest were acquired. The mean duration of the use of the CLE system was 7 minutes (range 3–18 minutes). Interpretable CLE images were obtained in all cases. The first interpretable image was acquired within a mean of 6 (SD 10) images and within the first 5 (SD 13) seconds of imaging; 4896 images (46%) were interpretable. Interpretable image acquisition was positively correlated with study progression, number of cases per surgeon, cumulative length of CLE time, and CLE time per case (p ≤ 0.01). The diagnostic accuracy, sensitivity, and specificity of CLE compared with frozen sections were 94%, 94%, and 100%, respectively, and the diagnostic accuracy, sensitivity, and specificity of CLE compared with permanent histological sections were 92%, 90%, and 94%, respectively. No difference was observed between lesion types for the time to first interpretable image (p = 0.35). Deeply located lesions were associated with a higher percentage of interpretable images than superficial lesions (p = 0.02). The study met the primary end points, confirming the safety and feasibility and acquisition of noninvasive digital biopsies in all cases. The study met the secondary end points for the duration of CLE use necessary to obtain interpretable images. A neuropathologist could interpret the CLE images in 29 (97%) of 30 cases.

CONCLUSIONS

The clinical-grade CLE system allows in vivo, intraoperative, high-resolution cellular visualization of tissue microstructure and identification of lesional tissue patterns in real time, without the need for tissue preparation.
Natural history of posterior fetal cephaloceles and incidence of progressive cephalocele herniation
Authors: Gadgil Nisha , McClugage Samuel G. , Aldave Guillermo , Bauer David F. , Weiner Howard L. , Huisman Thierry A. G. M. , Sanz-Cortes Magdalena , Belfort Michael A. , Emrick Lisa , Clark Gary , Joyeux Luc , Whitehead William E.
Published: July 2022

OBJECTIVE

In utero repair of fetal posterior cephaloceles (meningocele and encephalocele) is being performed based on the premise that fetal surgery prevents progressive herniation of neural tissue and brain damage during pregnancy. However, the extent to which progressive herniation occurs during pregnancy, specifically from prenatal diagnosis to after delivery, is not well known. The objective of this study was to describe the natural history of patients with fetal cephaloceles focusing on the incidence of progressive herniation.

METHODS

The authors conducted a retrospective cohort study of all patients referred to their center for posterior fetal cephalocele between 2006 and 2021. All patients underwent prenatal and postnatal MRI. Progressive herniation (primary outcome) was defined as an increase in the absolute volume of neural tissue within the cephalocele of > 5% or new herniation of a critical structure into the cephalocele. Total brain and cephalocele volumes were calculated to determine herniation progression from prenatal to postnatal MRI. Information on the presence of hydrocephalus, epilepsy, and developmental delay (secondary outcomes) was collected at 1 year of age.

RESULTS

Twenty patients met all study criteria. Ten patients (50%; 95% CI 0.27–0.73) demonstrated progressive herniation from prenatal to postnatal MRI. Three patients with progressive herniation were diagnosed with a meningocele prenatally and had an encephalocele postnatally. Two patients without progression had meningocele identified prenatally that regressed and became atretic by birth. Both prenatal hindbrain herniation (p = 0.03) and prenatal microcephaly (p = 0.05) were predictive of progressive herniation. The rates of hydrocephalus (44%), epilepsy (44%), and developmental delay (63%) were not associated with the occurrence of progressive herniation in this study.

CONCLUSIONS

In this study, progressive herniation was not a rare event (50%). Fetal hindbrain herniation and fetal microcephaly were associated with the occurrence of progressive herniation. These results support further investigations into why progressive herniation occurs in utero and if progressive cerebral herniation in utero plays a significant role in determining clinical outcome.
YOUTH LEISURE DURING COVID-19: THREE CREATIVE IMPRESSIONS FROM UKRAINE
Authors: Havryliuk Alla , Pletsan Khrystyna , Skachenko Olena , Rybka Anna
Published: July 2022

The purpose of the article is to study the impact of the COVID-19 pandemic on the organisation of leisure of Ukrainian youth. The research methodology is based on a comprehensive analysis of the national system of actions to prevent the spread of coronavirus infection, implemented by the Ukrainian government; analytical, structural and logical, comparative methods that allowed us to consider the legal status, educational and leisure activity of young people in Ukraine, international experience of youth participation in social projects to counter the spread of COVID-19; the method of theoretical generalisation, used to summarise the results; cultural approach, which helped to identify factors of influence of national measures on the activities of cultural and creative industries. Scientific novelty. In this study, we present three creative initiatives of Ukrainian youth to organise their own leisure activities, which were launched during the lockdown and created on the basis of the rich potential of national cultural heritage and folk traditions. Conclusions. In response to the challenges of the COVID-19 pandemic, the Ukrainian state has developed a system of measures to prevent it. Despite a large number of places for leisure, sports, and creative activities in Ukraine, lockdown restrictions and bans caused by COVID-19 led to their closure, and young people focused on leisure at home, creative self-development, and selforganisation of their free time. It is determined that the best international experience of youth activity in countering the challenges of the COVID-19 pandemic is realised mainly in the social dimension. The young people of Ukraine do not stand aside from the global challenges of our time, but initiate unique creative developments under pandemic conditions. Ukrainian creative initiatives are presented, including the online project #GlobalLesyaUkrainka2021 and the successful experience of self-organisation of leisure activities by students of the Kyiv National University of Culture and Arts (Challenge#Lovynamysto and Winter Magic Fest).
Cloud LMS of Statistic Data Visualization
Authors: Bulyha Kostiantin , Bulyha Olena , Kotsiubivska Kateryna
Published: July 2022

The purpose of the article is to create a cloud LMS (Learning Management System) analysis and visualization of statistics.
The research methodology is cloud information processing technologies.
The novelty of the research is the implementation of a new training course on the use of modern means of data visualization in the form of cloud LMS.
Conclusions. The material presented in the article gives a clear example of cloud technology usage in distance education. The materials of the training course “Information and Analytical Programs and Services” are implemented in the form of a cloud LMS based on the Google Classroom platform using a modern structure of material presentation.
Innovative Approaches to Distance Learning of Cultural and Artistic Profile Students
Authors: Ivashchenko Olena , Podhaietska Viktoriia , Buriak Bohdan
Published: July 2022

The purpose of the study is to identify innovative approaches to distance learning for cultural and artistic students.
Research methodology. Research methods are methods of observation and analytical and pedagogical research, a systematic approach and generalization while studying the problem of implementing innovative teaching methods during distance education.
Scientific novelty. It is determined that during the preparation of cultural and artistic students, based on the application of innovative approaches, it is recommended to teach theory and practical work, i. e. process, simultaneously. It is defined that in the process of professional training of cultural and artistic profile students, the teachers apply professionally-oriented interactive game methods.
Conclusions. It has been established that the innovative approach consists in modern modelling, organisation of non-standard lectures and practical, seminar classes. It has been determined that the implementation of an innovative approach is a complex process due to a large number of variables that should be taken into account both in the course and at the individual level. It has been determined that the transition to distance learning, based on the application of an innovative approach, will be useful for both students and teachers of cultural and artistic profiles. It has been found that after completing the curriculum during the preparation of cultural and artistic students based on an innovative approach, the future specialist should develop skills in such profile dimensions as creation, implementation and evaluation and analysis. It has been determined that as a result of training students of cultural and artistic profiles based on an innovative approach, they will gain the following key skills: communication skills, analytical, open mind and ability to transcend limits and experiment with new ideas, creativity, criticism and research skills, self-awareness, self-presentation, ability respond effectively to feedback, teamwork and collaboration, thinking skills, time management and organizational skills, resilience and self-discipline.
Application of Universal Design in the Development of Web-oriented Information Resources
Authors: Borodkina Iryna , Borodkin Heorhii
Published: July 2022

The purpose of the article is to analyze and reveal the essence of the application of the principles of universal design in the development of web-based information resources.
Research methodology. To achieve the goal of the study, an analytical method was used, which allowed us to analyze the principles of universal design and determine the features of their application in the development of web-based information resources.
The scientific novelty is that the article has developed the principles of universal design in terms of their use in the development of web-based information resources.
Conclusions. The existing problems and prospects of the universal design principles’ application during the development of web-oriented information resources are analyzed. Taking into account the results of the analysis, a system of recommendations has been developed to be followed for improving the conditions of use and availability of web-based information resources.
Modern University Libraries as Centres of Communication: Scientific Aspect
Authors: Salata Halyna
Published: July 2022

The purpose of the article is to study modern university libraries as centres of communication through the prism of scientific and social aspects.
Research methodology. To implement this task, some theoretical and general scientific research methods were used, among which we note the analysis, synthesis, induction and deduction, and concretization. Equally important was the method of comparison, which was used to compare the practice of using university libraries in Ukraine and other European countries. The method of abstraction used in the analysis of general theoretical approaches and the formation of recommendations for the use of university libraries in modern higher education institutions in Ukraine involves the ascent from abstract ideas to concrete facts.
Scientific novelty. For the first time, an important and underestimated development vector of the scientific space of university libraries was noted, which will allow optimizing their activities in the future, transforming them from ordinary reading rooms into a creative scientific space, profitable and accessible to visitors.
Conclusions. The article considers the peculiarities of the modern university libraries functioning through the prism of the communicative function. The main focus is on the transformation of the library space and its focus on modern requirements for the formation of creative “territory” for scientific conferences, including international, free exchange of views during student tournaments, excursions and celebrations, seminars or lectures, etc. It has been established that university libraries in modern conditions are universal institutions that perform much broader functions of information retrieval than previously thought. Until now, the academic community has not been sufficiently aware of this process. As the analysis of several projects has shown, in modern conditions it is possible to further develop this aspect.
How to Persuade the Students to Read Complicated Texts: An Experience Drawn from the Use of Digital Technologies
Authors: Radaev V. V.
Published: July 2022

With the inflow of the new generations of students, university teachers in social sciences and humanities have been challenged by a crisis of textual culture given the students tend to increasingly avoid reading complicated academic texts. In these circumstances, traditional arrangements of seminars and students’ homework are becoming less effective. This paper is aimed at exploring the new capacities for coping with the new critical situation. We address the issue of why we should keep the practices of active reading and how examination of complicated academic texts contribute to the formation of the students’ critical thinking. Both the special literature and personal teaching experience of the author are attracted. Traditional forms of teaching arrangements are analyzed. Then we use an experience of a digital platform to demonstrate the potential ways of resolving the teaching problems. They include active reading dealing with the reflexive work, interactive discussions in the class and in the virtual environment. We also show that additional efforts associated with the use of digital technologies pay back enabling the teacher to control the students’ homework more effectively and provide a more adequate assessment of the educational outcomes.
Die Einstellung von Verwaltungsmitarbeiter/innen zu Online-Partizipation im Spannungsfeld zwischen Öffentlichkeit und Bürokratie / The attitudes of government employees towards online participation between the public sphere and bureaucracy
Authors: Nguyen Phillip
Published: July 2022

Infolge von Entwicklungen wie Vertrauensdefiziten gegenüber etablierten Entscheidungsprozessen und der fortlaufenden Digitalisierung wird elektronische Bürgerbeteiligung durch die Kommunalverwaltungen zunehmend fokussiert. Trotz des Potenzials der Einbeziehung von Bürger/innenmeinungen zeigt sich eine große Heterogenität in Bezug auf die Anzahl, den Umfang und den Erfolg von Online-Partizipation. Um die Institutionalisierung und den Erfolg zu fördern, ist die Einstellung der Kommunalverwaltungsmitarbeiter/innen von zentraler Bedeutung. Die Studie untersucht mithilfe eines qualitativen Forschungsdesigns, aus welchen Inhalten sich die Einstellung der Mitarbeiter/innen gegenüber Online-Partizipation zusammensetzt und wie diese entsteht. Dazu werden Aspekte wie die konkrete Arbeit an den Verfahren, der organisationale Kontext, die berufliche Sozialisation oder individuelle Faktoren analysiert. Aufgrund der Relevanz für die Durchführung der Verfahren werden dabei die verantwortlichen Mitarbeiter/innen der Fachbereiche für Bürger/innenbeteiligung betrachtet. Die Ergebnisse zeigen eine hohe Relevanz von individuellen Eigenschaften, der Verwaltungsführung sowie der Bürger/innen als Adressat/innen der Projekte.
CHAMEO: An ontology for the harmonisation of materials characterisation methodologies
Authors: Del Nostro Pierluigi , Goldbeck Gerhard , Toti Daniele
Published: July 2022

The field of materials characterisation encompasses a wide range of methods and related research communities. This has led to a proliferation of terminologies and data management approaches, hindering collaboration and interoperability. In this work, a domain ontology designed to model the common aspects across the different characterisation methodologies is presented. This ontology, called the CHAMEO ontology, is based on a recent CEN Workshop Agreement (CWA 17815) which introduced a standardised terminology and the Characterisation Data (CHADA) documentation scheme. The goal of CHAMEO is to provide a framework for harmonising the underlying method-specific ontologies, which can be developed by reusing and specialising the generic constructs of the CHAMEO ontology. This work is part of a broader initiative under the umbrella of the European Materials Modelling Council (EMMC), for the development of interconnected materials modelling ontologies based on a common root that is the Elementary Multiperspective Material Ontology (EMMO). The CHAMEO ontology was developed within the NanoMECommons European project that has the goal of harmonising characterisation protocols. The CHAMEO ontology has also been aligned with a number of recently developed, EMMO-based domain ontologies for the classification of materials, models, manufacturing processes and software products related to Materials Modelling. Availability. The axiomatization of the ontology is stored in a GitHub repository available at: https://github.com/emmo-repo/domain-characterisation-methodology, and is published at the following URL: http://emmo.info/emmo/domain/chameo/chameo.
go4cognition: Combined Physiological and Cognitive Intervention in Mild Cognitive Impairment
Authors: Lissek Vanessa J. , Ben Abdallah Heithem , Praetorius Arthur , Ohmann Tobias , Suchan Boris
Published: July 2022

Background: While cognitive interventions in mild cognitive impairment (MCI) show positive effects on cognitive performance, physical activity appear to slow down cognitive decline, suggesting a relationship between both factors. However, previous combined programs that have shown significant improvement in cognitive function in MCI have typically trained cognition and physical functioning separately. Objective: This project aimed at evaluating two group interventions combining the stimulation of physical and cognitive domains in individuals with MCI: Simultaneous stimulation of physical and cognitive skills in comparison to a standardized training, which stimulates cognitive and physical functions separately. Methods: The study was designed as a randomized controlled trial. The first group was trained on the SpeedCourt® system while the second group completed the standardized Fitfor100 program. Training was completed by a total of 39 subjects with diagnosed MCI as determined by the CERAD (SpeedCourt®: 24 subjects, Fitfor100:15 individuals). Results: There were significant improvements of physical factors (e.g., hand strength and balance) in both groups. Improvement in the CERAD total score allowed for a post interventional classification of all participants into non-MCI and MCI. This effect persisted over a period of three months. Both forms of intervention were found to be effective in improving various cognitive functions which persisted for a period of three months. Conclusion: Both evaluated non-pharmacological, multicomponent interventions, which combined physical and cognitive training in a social setting showed improvement of cognitive functions leading to a persistent classification of former MCI patients in non-MCI patients.
Costs of Persons with Dementia Living in Nursing Homes in The Netherlands
Authors: Klein Philip Charles Gerard , Huygens Simone , Handels Ron , Wester Valérie , Kanters Tim Andre
Published: July 2022

Background:

Disease modifying treatments (DMTs) currently under development for Alzheimer’s disease, have the potential to prevent or postpone institutionalization and more expensive care and might delay institutionalization of persons with dementia.

Objective:

The current study estimates costs of living in a nursing home for persons with dementia in the Netherlands to help inform economic evaluations of future DMTs.

Methods:

Data were collected during semi-structured interviews with healthcare professionals and from the financial administration of a healthcare organization with several nursing homes. Personnel costs were calculated using a bottom-up approach by valuing the time estimates. Non-personnel costs were calculated using information from the financial administration of the healthcare organization.

Results:

Total costs of a person with dementia per 24 hours, including both care staff and other healthcare providers, were € 151 for small-scale living wards and € 147 for independent living wards. Non-personnel costs were € 37 per day.

Conclusion:

This study provides Dutch estimates for total healthcare costs per day for institutionalized persons with dementia. These cost estimates can be used in cost-effectiveness analyses for future DMTs in dementia.
Alzheimer’s Disease: Risk Tests and the Medical Record
Authors: Zallen Doris T.
Published: July 2022

Although the medical record is the centerpiece of modern medical care, its usefulness is diminished by the reluctance of people to disclose important health information, such as a higher risk for Alzheimer’s disease, to their doctors. Steps should be taken now to ensure that the medical record, the repository of one’s health information, can continue to serve the needs of the medical community and of patients.
Resolving-power domination number of probabilistic neural networks
Authors: Prabhu S. , Deepa S. , Arulperumjothi M. , Susilowati Liliek , Liu Jia-Bao
Published: July 2022

Power utilities must track their power networks to respond to changing demand and availability conditions to ensure effective and efficient operation. As a result, several power companies continuously employ phase measuring units (PMUs) to continuously check their power networks. Supervising an electric power system with the fewest possible measurement equipment is precisely the vertex covering graph-theoretic problems otherwise a variation of the dominating set problem, in which a set D is defined as a power dominating set (PDS) of a graph if it supervises every vertex and edge in the system with a couple of rules. If the distance vector eccentrically characterizes each node in G with respect to the nodes in R, then the subset R of V (G) is a resolving set of G. The problem of finding power dominating set and resolving set problems are proven to be NP-complete in general. The finite subset R of V (G) is said to be resolving-power dominating set (RPDS) if it is both resolving and power dominating set, which is another NP-complete problem. The ηp (G) is the minimal cardinality of an RPDS of a graph G. A neural network is a collection of algorithms that tries to figure out the underlying correlations in a set of data by employing a method that replicates how the human brain functions. Various neural networks have seen rapid progress in multiple fields of study during the last few decades, including neurochemistry, artificial intelligence, automatic control, and informational sciences. Probabilistic neural networks (PNNs) offer a scalable alternative to traditional back-propagation neural networks in classification and pattern recognition applications. They do not necessitate the massive forward and backward calculations that ordinary neural networks entail. This paper investigates the resolving-power domination number of probabilistic neural networks.