bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychosocial Risk Factors and Cardiovascular Disease: Epidemiology, Screening, and Treatment Considerations
Authors: Rozanski Alan
Published: October 2016

The recognition that psychosocial risk factors contribute to the pathogenesis of cardiovascular disease has led to the development of a new field of behavioral cardiology. The initial impetus for this field was studies performed in the 1980s and 1990s that provided epidemiological evidence and a pathophysiological basis for a strong link between a number of psychosocial risk factors and cardiovascular disease, including depression, anxiety, hostility, job stress, and poor social support. In recent years, additional psychosocial risk factors have been identified, including pessimism; other forms of chronic stress, such as childhood abuse and trauma, and the psychological stress that may be associated with chronic medical illness; lack of life purpose; and the syndrome of “vital exhaustion,” which consists of a triad of exhaustion, demoralization, and irritability. New research in the last decade has also established that positive psychosocial factors, such as optimism, positive emotions, a vibrant social life, and a strong sense of life purpose, can have an important health-buffering effect through their favorable influence on health behaviors and promotion of positive physiological functioning. Patients can be screened for psychosocial risk factors in clinical practice through either the use of open-ended questions, which can be integrated into a physician’s standard review of systems, or the use of short questionnaires. Physicians can assist in the treatment of psychosocial risk factors in various ways, such as screening patients for psychological distress and making appropriate referrals when indicated, providing patients with practical lifestyle suggestions, and employing office personnel to teach patients behavioral or psychosocial interventions that can promote a sense of well-being and/or reduce stress.
Outcome Trials in the Therapeutic Management of Hypertension in East Asians
Authors: Wang Ji-Guang , Li Yan
Published: October 2016

According to the most recent epidemiological data, the prevalence of hypertension ranged from about 25% in Chinese living either in the mainland or in Taiwan and Koreans, to approximately 40% in Mongolians. The control rate of hypertension was about 35% in Koreans and Japanese, 24% in Mongolians, and less than 10% in Chinese. Four placebo-controlled trials in China unequivocally proved that antihypertensive therapy may prevent stroke and other cardiovascular complications in hypertension or patients with a history of stroke or transient ischemic attack. Four actively-controlled trials in Japan did not show significant difference between various classes or combinations of antihypertensive drugs. Two trials that compared intensive with less intensive blood pressure control in elderly Japanese hypertensive patients did not show further benefit of controlling systolic blood pressure to a level below 140 mmHg in comparison with blood pressure control to a level of 140 mmHg or above. These trials that compared various classes of antihypertensive drugs or intensive with less intensive blood pressure control often had small sample size and hence inadequate power to detect modest or moderate benefit. There is still a need for high quality outcome trial data in East Asians.
mTOR inhibitors response and mTOR pathway in pancreatic neuroendocrine tumors
Authors: Falletta Simona , Partelli Stefano , Rubini Corrado , Nann Dominik , Doria Andrea , Marinoni Ilaria , Polenta Vanessa , Di Pasquale Carmelina , degli Uberti Ettore , Perren Aurel , Falconi Massimo , Zatelli Maria Chiara
Published: October 2016

Medical therapy of pancreatic neuroendocrine tumors (P-NET) may take advantage of Everolimus treatment. However, the extent of therapeutic response cannot be predicted. This study was aimed to identify the possible predictive markers of response to Everolimus in P-NET. We found that Everolimus reduced the cell viability and induced apoptosis in primary cultures of 6 P-NET (P-NET-R), where the proliferative and antiapoptotic effects of IGF1 were blocked by Everolimus. On the contrary, 14 P-NET primary cultures (P-NET-NR) were resistant to Everolimus and IGF1, suggesting an involvement of PI3K/AKT/mTOR pathway in the mechanism of resistance. The response to Everolimus in vitro was associated with an active AKT/mTOR pathway and seemed to be associated with a greater clinical aggressiveness. In addition, a patient sensitive to Everolimus in vitro was sensitive to this drug in vivo also and showed a positive p-AKT immunohistochemistry (IHC) at tissue level. Similarly, a patient resistant to Everolimus treatment after surgery was not sensitive to the drug in vitro and had a negative p-AKT IHC staining. Therefore, present data confirm that P-NET primary cultures may be considered a model for testing medical treatment efficacy and that IHC characterization of p-AKT might help in identifying human P-NET who can benefit from Everolimus treatment. These data encourage conducting a prospective multicenter study involving different groups of P-NET patients treated with Everolimus.
Las nuevas fronteras de las commodities en Venezuela: extractivismo, crisis histórica y disputas territoriales
Authors: Teran Mantovani Emiliano
Published: October 2016

En el marco de una crisis histórica en Venezuela, se está produciendo una significativa reorganización geoeconómica del territorio alrededor del extractivismo: se trata de una expansión hacia las nuevas “fronteras de las commodities” en la cual se pretende incorporar a la megaminería entres sus más importantes actividades económicas. El artículo presenta rasgos y características de la actual expansión de frontera, desde la perspectiva de la ecología política y la economía ecológica, analizando también los factores históricos y coyunturales más determinantes de este proceso, así como las formas que toma la nueva cartografía del extractivismo en el país. Algunas modalidades discursivas, de apropiación de la naturaleza y de territorialización, derivadas de esta política sobre el “tejido de la vida” serán también examinadas. A su vez, se resaltan algunas potenciales consecuencias e implicaciones de estos procesos, haciendo énfasis en los daños socioambientales, el déficit ecológico nacional, y los diferentes conflictos y disputas producidas por ellos.
Fragmentación de las redes de innovación y dinámica de los sistemas territoriales de producción y de innovación en sectores tradicionales
Authors: Gallego Bono Juan Ramón
Published: October 2016

Para competir en la globalización, los sistemas territoriales de producción en sectores tradicionales deben convertirse en sistemas territoriales de producción y de innovación. Esto supone urdir redes de innovación más complejas entre actores heterogéneos (empresas, universidades, centros tecnológicos, etc.), lo que genera una tensión política de integración/fragmentación de dichas redes. Para contrastar esta hipótesis se combinan los enfoques evolucionista y del actor-red con el enfoque de la proximidad. La construcción de redes de innovación más amplias exige desarrollar nuevas comunidades de práctica. Este proceso puede generar una dinámica de fragmentación por medio del establecimiento de relaciones estables y selectivas entre diferentes conjuntos de actores, formando coaliciones entre comunidades de práctica y grupos organizados. Pero esta misma interrelación entre comunidades de práctica y grupos organizados abre posibilidades de cooperación que pueden favorecer una dinámica integradora a través del enrolamiento de nuevos actores y competencias. La pertinencia de este marco se evidencia con el estudio longitudinal de los sistemas territoriales citrícola y cerámico de la Comunitat Valenciana (España). Si las redes de innovación presentan una cierta fragmentación en el primer caso, en el segundo predomina su integración. Pero la mayor variedad investigadora del primero contrasta con los riesgos de lock-in del segundo situado en una trayectoria tecnológica única aunque de creciente complejidad.
Entendiendo la evaluación de la espera desde la psicología del consumidor: efectos de las expectativas y los llenadores de tiempo
Authors: Alvarado Valencia Jorge Andrés , Trespalacios Leal María Carolina
Published: October 2016

Uno de los factores más importantes que afecta la satisfacción del usuario con un servicio es la evaluación de la espera, entendida como la diferencia entre percepción y expectativa. Dicha evaluación tiene efectos inmediatos en la satisfacción del cliente con el servicio de una empresa. El presente estudio evaluó los efectos generados por dos tipos de llenadores de tiempo y la heurística de anclaje y ajuste en la evaluación de la espera en un servicio de bajo costo. Los resultados muestran que la expectativa de espera del usuario presenta efectos significativos en la percepción de dicho tiempo —mediados por la heurística de anclaje y ajuste—, mientras que el uso de llenadores de tiempo no tuvo efectos notables ni en la percepción ni en la evaluación del tiempo de espera. Como conclusión se sugiere que las empresas que operan en ambientes de autoservicio consideren en primera medida alternativas en el diseño de sus ambientes de servicio basadas en la generación de expectativas adecuadas a la satisfacción del usuario, y solo en menor medida consideren alternativas basadas en disminuir el tiempo percibido.
Atributos relevantes de la calidad en el servicio y su influencia en el comportamiento postcompra. El caso de las hamburgueserías en España
Authors: Clemente-Ricolfe José-Serafín
Published: October 2016

El producto, los aspectos físicos, los empleados y la rapidez son las cuatro dimensiones que agrupan los atributos considerados en la evaluación de la calidad en el servicio de las hamburgueserías. Mediante un análisis de ecuaciones estructurales, se muestra que solamente el factor producto es determinante en la calidad del servicio. Sin embargo, la importancia dada a la información nutricional en este tipo de restaurantes permite obtener diferencias significativas. Por último, la calidad en el servicio se confirma como un factor importante para predecir el comportamiento postcompra.
Diseño y prueba de un cuestionario sobre la importancia percibida de las condiciones de trabajo en México
Authors: Tamayo Contreras Porfirio , Guevara-Sanginés Martha L. , Sánchez Santa-Bárbara Emilio
Published: October 2016

La percepción de la importancia que el empleado otorga a los distintos aspectos de su trabajo es una base de la representación social que tiene de la empresa en la que labora y de las actitudes hacia su trabajo, como la intención de abandono, que también se relacionan con aspectos no controlables por la empresa. El propósito de este estudio fue diseñar y probar un cuestionario para medir la importancia que los trabajadores conceden a los aspectos laborales e identificar su relación con la intención de abandonar la organización. El cuestionario se aplicó a 447 trabajadores (282 hombres y 165 mujeres) de empresas exportadoras de calzado de la ciudad de León, Guanajuato, México. Mediante un análisis factorial se identificaron cinco factores; la consistencia interna fue adecuada en todos los casos y la discriminación de todos los ítems resultó en la dirección esperada. La percepción sobre los factores del trabajo varió en importancia y no se relacionó con la intención de abandono, aunque un aspecto no controlable por la empresa (mejor salario) reveló indicios de una relación sobre la intención de abandono.
Mashland and aquatic plants of the artificial wetland within the municipal park in Skawina
Authors: Koziara Zbigniew
Published: October 2016

Observations of aquatic plants and marshland plants were conducted in an artificially formed
fen, within the old basin of Skawinka river, in a municipal park located in the southwest part
of Skawina town. The area selected for the study was determined based on the location of plant
stands, representative for the whole body of water. Based on the analysis of the locations where
the aquatic and marshland plants occurred, observations were made of selected species. When
making the selection, we were guided by the criterion of the potential suitability of using these
plants in garden plantings, planned subsequently. We have marked the locations of particular
plant communities, and then applied them on the situational and altitude map, in the scale of
1 : 500 [Czarnota 1997], which is the basis for the design and planting in the area.
PARAMETER POPULASI UDANG PUTIH (Penaeus merguiensis) DI PERAIRAN SAMPIT DAN SEKITARNYA, KALIMANTAN TENGAH
Authors: Nurdin Erfind , Kembaren Duranta D
Published: October 2016

Udang putih (Penaeus merguiensis)merupakan salah satu sumberdaya ekonomis penting di perairan Sampit. Pada saat ini alat tangkap yang efisien untukmenangkap udang adalah lampara dasar (danishseine) dan jaring tiga lapis (trammel net). Penelitian tentang tingkat pengusahaan udang putih telah dilakukan dari bulan Januari sampai bulan Nopember 2012. Penilaian estimasi parameter populasi udang putih menggunakan paket program “FAO – ICLARM Stock Assessment Tools” atau FISAT - II. Hasil analisis diperoleh nilai laju pertumbuhan (K) sebesar 1,45 per tahun dengan panjang karapas asimtotik (CL”) 57,8 mm. Laju kematian total (Z) sebesar 5,70 per tahun, laju kematian alamiah (M) sebesar 1,93 per tahun dan laju kematian akibat penangkapan (F) sebesar 3,77 per tahun. Tingkat pengusahaan udang putih di perairan Sampit telah mengalami lebih tangkap (over exploited) dengan nilai E sebesar 0,66. Udang putih sudah tertangkap terlebih dahulu sebelum mencapai ukuran pertama kali matang gonad (Lc=30,05 < Lm=39,4 mmCL). Kondisi ini mengindikasikan perlunya dilakukan pengelolaan yang hati-hati dan bertanggungjawab. Salah satu cara yang dapat ditempuh adalah denganmenerapkan sistem penutupan musim tangkapan, khususnya pada bulan Maret dan September, karena pada saat tersebut terjadi puncak pemijahan.White shrimp (Penaeus merguiensis) is one of the most valuable resources in the Sampit waters. At present danish seine and trammel net is an efficient gear available to catch shrimp. A study of exploitation of white shrimp was carried out from January to November 2012. Estimation of population parameter of white shrimp were analyzed by using program “FAO – ICLARM Stock Assessment Tools (FiSAT-II). The result showed that the value of growth rate (K) was 1.45/year with asymptotic carapace length (CL”) was 57.8 mm. Total mortality rate (Z) was 5.70/year, natural mortality rate (M) was 1.93/year and fishing mortality rate (F) was 3.77/year. Exploitation rate of white shrimp indicated overexploited (E=0.66). Moreover, these shrimp was fished before reaching the first size on maturity (Lc=30.05 < Lm=39.4 CLmm). This condition indicate that it is necessary to manage shrimp fisheries carefully and responsibly. It is recommended to apply a closed season system, especially on March and September when peak of spawning season occurred.
KEBIASAAN MAKAN DAN LUAS RELUNG BEBERAPA JENIS UDANG DAN IKAN DI PESISIR MUARA KAKAP, KALIMANTAN BARAT
Authors: Purnamaningtyas Sri Endah , Hedianto Dimas Angga
Published: October 2016

Sumberdaya udang dan ikan merupakan komoditas ekspor dari sektor perikanan dan merupakan sasaran utama bagi usaha penangkapan di Kalimantan Barat. Makanan merupakan kunci pokok bagi pertumbuhan dan kelangsungan hidup ikan. Tujuan penelitian ini adalah untuk mengevaluasi kebiasaan makan dan luas relung beberapa jenis udang dan ikan di perairan pesisirMuara Kakap, Kalimantan Barat. Pengambilan sampel udang dan ikan diperoleh dari hasil tangkapan nelayan yang didaratkan di Tempat Pelelangan Ikan sebanyak 4 kali ulangan (Maret, Juni, September dan November 2012). Metode analisis yang digunakan untuk mengetahui kebiasaan makan ikan adalah kombinasi antara analisis kualitatif dan kuantitatif dengan menggunakan indeks bagian terbesar (Indeks of Preponderance) dan estimasi tingkat tropik jens ikan menggunakan analisis pengelompokkan (dendogram) berdasarkan pada jarak euklidean pautan lengkap (complete linkange). Hasil penelitian menunjukkan bahwa kelompok udang di perairan ini umumnya pemakan bangkai (scavenger) berupa sisa-sisa organisme hewanimaupun nabati yang berada di dasar perairan. Ikan di perairan banyakmemanfaatkan krustasea, tumbuhan dan cacing sebagai sumber makanannya, sehingga peluang terjadinya kompetisi sangatrendah, baikmakanan maupun ruang.Shrimp and fish resources are export commodities of the fisheries sector and are a main target for fishing effort inWest Kalimantan. Food is an important key to the growth and survival of fish. The purpose of this study was to evaluate eating habits and extensive niche some kind of shrimp and fish in the coastal waters of Muara Snapper,West Kalimantan. Samples were obtained from shrimp and fish catches of fishermen landed at the fish auction place as much as 4 replications (March, June, September and November 2012). The analytical method used to determine the feeding habits of fish is a combination of qualitative and quantitative analysis using the lion’s share index (index of preponderance) and estimated trophic level of fish jens using clustering analysis (dendogram) based on the Euclidean distance of the complete linkage (complete linkange). The results showed that the group of shrimp in these waters are generally scavengers (scavenger) in the form of remnants of animal and vegetable organisms that are in the bottom waters. The fish in the waters of many utilizing crustaceans, plants and worms as a source of food, so the chances are very low competition, good food and space.
KARAKTERISTIK BIOLOGI IKANTONGKOLKOMO(EUTHYNNUSAFFINIS) YANGTERTANGKAPJARINGINSANGHANYUTDILAUTJAWA
Authors: Masuswo Rudy , Widodo Agustinus Anung
Published: October 2016

Tahun 2015 telah dilakukan penelitian tongkol komo (Euthynnus affinis) yang tertangkap jaring insang hanyut berukuran mata jaring 4 inci di Laut Jawa berbasis di PPI Karangsong Indramayu. PPI Karangsong adalah basis perikanan jaring insang di Indramayu dengan daerah penangkapan utama di perairan Laut Jawa. Penelitian ini bertujuan untuk mengetahui karakteristik biologi yang meliputi: distribusi ukuran,  ukuran pertama kali matang gonada (Lm) dan ukuran pertama kali tertangkap (Lc) dan parameter biologi lainnya yaitu hubungan panjang (FL)-bobot (W) ikan dan nisbah kelamin.  Hasil penelitian menunjukkan bahwa distribusi ukuran  ikan antara 27 – 58 cmFL (rata-rata 45,5) dengan median 44 cmFL, Lm tongkol jantan  45,8 cmFL dan betina 43,2 cmFL, ukuran Lc 44,5 cmFL, hubungan panjang-bobot menurut persamaan W= 0,0636 L2,6497 (r2=0,8409) dengan nisbah kelamin jantan: betina 52 : 48 %.

A research of kawa-kawa (Euthynnus affinis) caught by 4 inche mesh size drifting gillnets operate in Jawa Sea waters based at Karangsong-Indramayu has been carried out in 2015. Karangsong is a gill net fishery based in Indramayu with a major fishing area in the waters of the Java Sea. The aim of research is to determine the biological carachteristics wich cover: size distribution, length of first matured (Lm) and length of first captured (Lc), L-W relationship and sex ratio.  The result show that length distribution ranged 27-58 (ave. 45.5) with median 44 cmFL, the Lm of male and female of kawa-kawa were 45.8 cmFL and 43,2 cmFL respectively and the Lc was 44.5 cmFL, L-W relationship was W= 0.0636 L2.,6497(r2=0.8409), and sex ratio male : female was 52 : 48 %.
AUSIES TRIMITO FUNKCIJOS VERTINIMAS ASMENIMS SU PASUNKĖJUSIU KVĖPAVIMU PER NOSĮ, ATLIEKANT IDEALIOS SEKOS DAŽNIŲ SONOTUBOMETRIJĄ
Authors: Beleškiene Vilma , Lesinskas Eugenijus
Published: October 2016

Reikšminiai žodžiai: ausies trimito tyrimai, sonotubometrija, pasunkėjęs kvėpavimas per nosį. Sonotubometrija yra vienas objektyvių ausies trimito ventiliacinės funkcijos tyrimo metodų, kai funkcijai įvertinti naudojamas garsas ir jo intensyvumo pokyčiai atsiveriant ausies trimitui. Darbo tikslas – įvertinti sonotubometrijos tyrimo rezultatus naudojant idealios sekos dažnius asmenims su nosies pertvaros iškrypimu ir pasunkėjusiu kvėpavimu per nosį bei nustatyti veiksnius, galinčius turėti įtakos gaunamiems rezultatams. Ištirta 42 asmenys, kurie gydėsi dėl pasunkėjusio kvėpavimo per nosį, bei 37 sveiki kontrolinės grupės asmenys. Buvo renkama tiriamųjų anamnezė, atliekama otoskopija, rinoskopija, timpanometrija, Valsalvos testas. Nosiaryklės videoendoskopijos metu vertinti nosiaryklės ir ausies trimito angos morfologiniai požymiai, angos atsidarymo kokybė. Sonotubometrijai naudota plačiajuostė radijo signalų sistema (idealios sekos dažniai), 15 sekunžių 71 dB intensyvumo garsas. Mėginiui įvertinti tiriamųjų buvo prašoma ryti seiles 5 kartus. Ausies trimito atsidarymas sonotubometriškai užregistruotas 65,5 proc. tiriamųjų (kontrolinė grupė – 93,2 proc., p < 0,001). Vidutinė ausies trimito atsidarymo trukmė buvo 260 ms (SD ± 151), garso intensyvumo pokytis 10,59 dB (SD ± 4,78). Pasunkėjusio kvėpavimo per nosį ir sveikų asmenų grupėse buvo skirtingų sonotubogramų tipų. Ausies trimito fiksuoto atsidarymo rezultatai buvo blogesni asmenims su pasunkėjusiu kvėpavimu per nosį, stipriai išreikštu nosies pertvaros iškrypimu, apatinių nosies kriauklių edema, taip pat tais atvejais, kai fiksuota nosiaryklės ir ausies trimito ryklinės angos gleivinės edema limfoidinio audinio perteklius.
RADIOLOGINĖ PAMATO BRANDUOLIŲ POKYČIŲ DIFERENCINĖ DIAGNOSTIKA
Authors: Janiūnienė Eglė , Ulytė Agnė , Dementavičienė Jūratė , Valaikienė Jurgita
Published: October 2016

Reikšminiai žodžiai: pamato branduoliai, magnetinio rezonanso tomografija, kompiuterinė tomografija, diferencinė diagnostika. Pamato branduoliai – simetriškos požievinės giliosios pilkosios medžiagos sankaupos galvos smegenyse, sudarančios ekstrapiramidinės sistemos pagrindą. Pagrindiniai pamato branduoliai yra uodeguotasis (nucleus caudatus) ir lęšinis (nucleus lentiformis), kurį sudaro kiautas (putamen) ir blyškusis kamuolys (globus pallidus). Pagrindinė pamato branduolių funkcija yra valingų judesių atlikimo (pradžios, amplitudės, greičio) kontrolė. Dėl to jų pažeidimas įprastai pasireiškia hipokinezija arba hiperkinezija. Esant dideliam pažeidimui, pastebimi ir kiti mažiau specifiški simptomai – nuo sąmonės sutrikimo iki komos. Šiame straipsnyje apžvelgiame pamato branduolių kompiuterinės tomografijos ir magnetinio rezonanso tomografijos vaizdus normos ir dažniausių, mažiau žinomų bei išskirtinių patologijų atvejais. Aprašomos patologijos ir būklės iliustruojamos pavyzdžiais iš Vilniaus universiteto ligoninės Santariškių klinikų radiologinių vaizdų archyvo. Kompiuterinės tomografijos vaizduose pamato branduoliai yra izodensiniai smegenų žievės atžvilgiu, magnetinio rezonanso tomografijos sekose – izointensiniai smegenų žievės atžvilgiu. Blyškiojo kamuolio signalo intensyvumas gali būti kiek mažesnis nei kiauto. Senyvo amžiaus žmonėms dažnas normalus radinys yra hiperintensinis pamato branduolių T1, hipointensinis T2 sekos signalas, atsirandantis dėl fiziologinės kalcifikacijos ir geležies kaupimo. Signalo pokyčius taip pat gali sukelti hipoksija (pvz., hipoksinė išeminė encefalopatija arba apsinuodijimas anglies monoksidu), metabolinės ligos (hipoglikemija, hiperbilirubinemija, Leigh ir Vilsono ligos), mielino pažeidimas (Canavan liga, Krabbe lizosominė kaupimo liga, ekstra-pontinė mielinozė) ir kitos būklės (Wernicke encefalopatija, Creutzfeldt-Jakob liga, pirminė smegenų limfoma, smegenų toksoplazmozė ir kt.). Vienpusiai pokyčiai dažniau reiškia vietinį pažeidimą – insultą, tačiau taip pat gali būti neketoninės hiperosmosinės hiperglikemijos sindromo, Rasmuseno encefalito atvejais. Gali būti ir išimčių – vienpusiu pažeidimu gali pasireikšti ir sisteminės ligos. Diferencijuoti pamato branduolių radiologinius pokyčius yra sudėtinga, tačiau įmanoma pasinaudojus klinikine informacija bei prisiminus juos pažeidžiančių ligų spektrą. Svarbu nustatyti, ar pokyčiai vienpusiai, ar abipusiai. Abipusis pažeidimas yra dažnesnis, beveik visada lemia sisteminės ligos.
Banho no leito de infartados: crossover do controle hidrotérmico 40ºC versus 42,5º
Authors: Silva Cleivison José Barbosa da , Silva Monyque Évelyn dos Santos , Reis Fernanda Faria , Miranda Gabriela Cristina Oliveira de , Santos Luiz dos , Lima Dalmo Valerio Machado de
Published: October 2016

Objetivo: Comparar repercussões da temperatura da água do banho no  leito  do  paciente  infartado  sobre  variáveis  oxi-hemodinâmicas.  Método:  Crossover 2X2, intervenções: banho no leito com temperatura da água constante a 40°C (BL1) e 42,5°C  (BL2)  em  20  pacientes  acometidos  por  infarto  agudo  do  miocárdio  (IAM). Variáveis  dependentes:  oximetria  de  pulso,  frequência  cardíaca  (FC) e  temperatura axilar (Tax). Estatística inferencial pela análise de variância de medidas repetidas e teste de Bonferroni; nível de significância de 5%. Resultado: A SpO2 e Tax foi maior após o BL2  (p<0.05)  quando  comparado  ao  BL1.  O  BL2  reduziu  a  FC  em  1%  (p=0.01). Discussão:  O  banho  individualizado  com  controle  da  temperatura  da  água  é  capaz  de minimizar o impacto oxi-hemodinâmico. Conclusão: o banho com temperatura da água a 42,5ºC revelou-se mais vantajoso em relação ao 40°C no que tange ao SpO2, FC e Tax em pacientes infartados.
Aspectos demográficos e sociodemográficos de mulheres em situação de violência conjugal: estudo descritivo
Authors: Estrela Fernanda Matheus , Gomes Nadirlene Pereira , Gusmão Maria Enoy Neves , Lirio Josinete Gonçalves dos Santos , Couto Telmara Menezes , Cerqueira Tamiris Pereira
Published: October 2016

Objetivo: identificar os aspectos demográficos e socioeconômicos de mulheres em situação de violência conjugal. Método: Trata-se de um estudo descritivo e quantitativo,  vinculado  a  um  projeto  de  pesquisa-ação  sob  financiamento  da  Fundação de  Amparo  à  Pesquisa  do  Estado  da  Bahia.  Realizou-se  uma  pesquisa documental  a partir   de   informações   contidas   em   212   processos   registrados   em   2014   sob   a jurisprudência da 1ª Vara de Violência Doméstica e Familiar contra Mulher de Salvador. A análise dos dados foi efetuada por meio das distribuições das frequências. Resultado: A investigação dos processos registrados em 2014 revelou que a denúncia da violência conjugal  é  realizada,  na  sua  maioria,  por  mulheres  com  idade entre  25  e  49  anos, negras, solteiras, mães, que concluíram pelo menos o nsino médio e com vencimento de até  dois  salários  mínimos.  Discussão:  A  esse  perfil  de  mulheres,  já  sensibilizadas  para romper com a violência, devem ser investidas ações para que não desistam de lutar por uma vida livre de violência.
A higiene corporal da criança com encefalopatia pelos familiares: método criativo sensível
Authors: Coutinho Katia Aparecida Andrade , Pacheco Sandra Teixeira de Araújo , Rodrigues Benedita Maria Rêgo Deusdará , De Moraes Juliana Rezende Montenegro Medeiros
Published: October 2016

Objetivo:  Descrever  as  práticas  relativas  à  higiene  corporal  da criança  com  encefalopatia  no  domicílio.  Método:  Estudo  qualitativo  desenvolvido  pelo método criativo e sensível, com dados gerados de fevereiro a abril de 2014, através da dinâmica  Corpo  Saber,  com  cinco  grupos  familiares  de  crianças  em  acompanhamento ambulatorial em um hospital municipal do Rio de Janeiro, e analisados segundo a análise de discurso francesa. Resultados: A higiene corporal foi contextualizada pelos familiares em  múltiplas  dimensões  como:  escolha  do  horário  para  higiene,  locais  e  adaptações necessárias  para  realização,  dimensão  afetiva  empreendida  ao  banho  e  o  banho  da criança com gastrostomia. Discussão: Para os familiares, a higiene corporal apresentou-se  como  um  cuidado  complexo,  pois  envolveu  rotinas  e  adaptações  relativas  às demandas  das  crianças,  porém  oportunizou  momentos  de  relaxamento  e  brincadeira. Conclusão: As marcas culturais de cada família sustentaram suas práticas de cuidados, apontando os desafios determinados pela complexidade do cuidado frente às demandas da criança.
Efficacy of medication for therapeutic angiogenesis in combined treatment of patients with diabetes mellitus and critical limb ischemia
Authors: Kalinin R E , Suchkov I A , Pshennikov A S , Mzhavanadze N D , Krylov A A , Plaksa I L , Deev R V
Published: October 2016

The combination of peripheral atherosclerosis and diabetes mellitus is a severe pathology, characterized by a high rate, mortality and social significance. The results of limb salvage and distant survival in this pathology in a remote period are unsatisfactory in spite of all existing treatment methods. Clinical trials in previous years have shown efficacy and safety of the medication, which is a plasmid construct with the gene encoding vascular endothelial growth factor - kambiogenplasmid, in patients with disease stage IIa-III according to the A.V. Pokrovsky and Fontaine classification, who were not indicated for surgical treatment. The article presents the clinical cases of successful use of this drug for therapeutic angiogenesis in patients with critical limb ischemia and severe type 2 diabetes mellitus. The inclusion of therapeutic angiogenesis in the conservative treatment algorithms is promising for the treatment of this group of patients. There is a need for further research on the efficacy and safety of the medication in patients with peripheral atherosclerosis and diabetes mellitus in a remote period.
Effectiveness of sub-tenon’s administration of an angiogenesis inhibitor in treatment of wet age-related macular degeneration
Authors: Gaybaryan R V , Epikhin A N , Bondarenko Yu F
Published: October 2016

Aim. To study the clinical results of the administration of an angiogenesis inhibitor into sub-Tenon’s space on the viscous carrier.Methods. The study was conducted in two stages. At the first stage, analysis of examination and treatment of 32 patients (34 eyes) with the wet age-related macular degeneration was conducted. Patients were injected the angiogenesis inhibitor (bevacizumab 12.5 mg) on the viscous carrier (1.0 ml of 2% hydroxypropylmethylcellulose solution) into the posterior sub-Tenon’s space. At the second stage, a retrospective analysis of the treatment results of 30 patients (30 eyes) with the wet age-related macular degeneration, who received the standard monotherapy in the form of 3 monthly intravitreal injection of angiogenesis inhibitor (0.5 mg ranibizumab), and then according to indications, was conducted. The best-corrected visual acuity and optical coherence tomography data over the period of 12 months were evaluated.Results. When comparing the effectiveness of treatment, the mean best-corrected visual acuity significantly improved in both groups after treatment, and its final values were not significantly different. Also central retinal thickness, length, height and volume of lesions significantly decreased as a result of the treatment, and final values were not significantly different between the groups. The duration of the achieved clinical effect in sub-Tenon’s administration was 2-2.5 months, in intravitreal administration - 1-1.5 months.Conclusion. Administration of angiogenesis inhibitors into the posterior sub-Tenon’s space in wet age-related macular degeneration has an equivalent effectiveness to intravitreal introduction and at the same time provides more prolonged effect of medications.
Features of chronic hepatitis C course in pregnant women
Authors: Filipovich O M , Kuznetzov N I
Published: October 2016

Aim. To study features of the course of chronic hepatitis C virus infection in pregnant women and its effect on pregnancy.Methods. The study included 111 pregnant women: 67 with chronic hepatitis C and 44 healthy women. The mean age was 28 years. The number of pregnancies among examined women ranged from 1 to 8. All pregnant women had no concomitant therapeutic pathology and various addictions (alcohol, nicotine, drugs). The viral load in pregnant women with chronic hepatitis C ranged from 3.18×102 to 2.4×107 IU/mL.Results. Alanine aminotransferase and bilirubin levels in the group of chronic hepatitis C and in healthy pregnant women did not exceed the normal range and were not statistically different from each other. In repeated pregnancies viral load of hepatitis C virus was lower, compared with the first pregnancy: median [25%; 75%] = 5.202 [4.079; 6.364] and 6.658 [5.708; 7.380], respectively (p106 IU/mL). At the same time threatened miscarriage, intrauterine hypoxia and preeclampsia were registered more often.Conclusion. In the first pregnancy the viral load is higher than in repeated pregnancies; pregnancy in women with chronic hepatitis C without concomitant diseases does not cause activation of the inflammatory process in the liver; in pregnant women with chronic hepatitis C, especially at higher viral loads, medical history remarkable for obstetric diseases are more likely detected.
Need for parodontitis treatment in adult population and compliance with it
Authors: Biktimerova O O
Published: October 2016

Aim. Investigate the need of the population for treatment of inflammatory parodontal diseases and the degree of motivation and compliance with treatment and following the dentist’s recommendations.Methods. 427 patients aged 18 to 85 were evaluated by means of the index of assessment of periodontal tissues’ state (CPITN, 1980) and the questionnaire. Patients were divided into two groups: the first group included 143 people diagnosed with parodontitis who had previously received parodontal treatment, and the second group consisted of 284 patients who were not previously aware of their periodontal status. All obtained numerical values were subjected to statistical analysis.Results. Symptoms of periodontal inflammation were identified in 84.5% of cases, in most cases moderate severity of periodontitis was diagnosed. Severity of inflammation of the periodontal tissues is similar in males and females, besides there is no significant difference in inflammation signs observed in patients older than 45 years. Despite the fact that the patients of the first group knew about their disease, their degree of motivation in oral hygiene does not differ from that of patients from the second group who have periodontitis of almost the same severity, but did not know about the disease or did not go to a dentist complaining of periodontium pathology. Despite the 100% motivation in oral hygiene of patients previously diagnosed with periodontitis only 50% of them take regular treatment and preventive measures and demonstrate compliance with treatment and prevention.Conclusion. Obtained data demonstrate the significant need for periodontal treatment along with poor compliance with prescribed treatment.
Heat shock proteins - participants in osteoarthrosis pathogenesis
Authors: Kabalyk M A , Gel’tser B I , Osipov A L , Fadeev M F
Published: October 2016

Osteoarthrosis is a disease that affects all tissues of synovial joints, resulting in chronic pain and often a need for replacement. The high prevalence and the lack of reliable conservative approaches impose significant economic sanctions on most economies in the world. Currently the mechanisms of osteoarthrosis progression have been well studied. At the same time, the known pathogenetic concepts do not allow to define reliable targets of conservative treatment. There is a clear need for searching alternative concepts, which will help to expand the understanding of the pathogenesis and identify ways to address therapeutic issues. Heat shock proteins (chaperones) are involved in intra- and extracellular signaling in the pathogenesis of many diseases. The aim of this review is to analyze the current state of the problem of studying the role of heat shock proteins in the pathogenesis of osteoarthrosis. The review considers the fundamental aspects of the activation and functioning of chaperones, experience of studying chondrocyte heat shock proteins is described, issues of programmed cell death mechanisms are mentioned, scheme of shaperone activity in osteoarthrosis is illustrated. The role of heat shock proteins from the perspectives of reparation and alteration carried out in the articular cartilage is described, the prospects for further clarification of their role in the pathogenesis of osteoarthrosis are identified. The role of two key molecules - protein with molecular weight of 70 kD and a small molecule with molecular weight of 27 kD, is emphasized. Heat shock proteins are of fundamental and applicative interest from the perspective of their participation in the key ways of osteoarthrosis pathogenesis and phenomena (oxidative, microcrystalline, hydrodynamical, stress, aging, etc.). Further study of heat shock proteins will allow to significantly expand the knowledge of osteoarthrosis and to identify ways of targeted therapy.
Chance and circularity in Hardy's "Tess" and "Jude" compared
Authors: Díez Medrano Conchita
Published: October 2016

Chance and circularity in Hardy's "Tess" and "Jude" compared
El estilo de Malinowski en "Los argonautas del Pacífico Occidental"
Authors: Fernández Álvarez Óscar
Published: October 2016

There are two reasons why there is interest in Malinowski's style. First, Malinowski was a principal inventor of the discipline of modern fieldwork and ethnography. Second, Malinowski is a man of many puzzles and contradictions. Malinowski ventured in the Argonauts of the Western Pacific, what became his characteristic style: a journey through the life cycle of an institution, led by a confident, always-present narrator and ethnologist. Our stylisic exploration is devoted to seeing the unity beneath puzzles, and once finding the patterns not immediately obvious, opening up new questions and further explorations.
Interrelación en la transmisión de textos épicos e históricos
Authors: Marcos Casquero Manuel Antonio
Published: October 2016

Interrelación en la transmisión de textos épicos e históricos
Noticia de un escritor leonés: Nemesio Fernández
Authors: Martínez Fernández José Enrique
Published: October 2016

Noticia de un escritor leonés: Nemesio Fernández
Analysis of surgical fixation of displaced proximal humerus fractures using PHILOS plate
Authors: Chodavarapu Lalith Mohan , Kashayi Chowdojirao Sreekanth , Gonu Avinash , Patnala Chandrasekhar , Chilakamarri Vijay Krishna
Published: October 2016

Background: The treatment of displaced proximal humeral injuries still throws challenges in identifying variables to prognosticate the outcome and optimizing a good clinical result. This study attempts to analyze the functional outcome of surgery of such fractures with proximal humeral interlocking system (PHILOS) plate and evaluate variables which help in predicting the prognosis.

Methods: This is a retrospective and prospective study of 30 patients with displaced proximal humerus fractures - 2 part, 3 part, 4 part and fracture dislocations according to Neer classification, surgically treated using PHILOS plate during 2011 and 2014. Evaluation of patients was done on follow-up by an independent observer for union by radiographs and functional assessment by Constant-Murley score and DASH (disabilities of the arm, shoulder and hand) score.

Results: The mean age of the patients was 40.4 years (range 18-65). 83.3% of the patients were male. The mean follow-up was 18.9 months (4-36 months). The mean Constant-Murley score and the DASH score were 76 and 16 respectively at the last follow-up. Our analysis showed that the patient’s age, delay in surgery, and Neer’s classification influenced the prognosis of the fracture. Medial metaphyseal extension in the fracture or an intact medial neck showed a better outcome. Complications were seen in 5 patients. Avascular necrosis was seen in 3 patients.

Conclusions: Osteosynthesis of displaced proximal humeral fractures with PHILOS plate provides a good outcome, with low complication rate. Patient’s age and the type of fracture based on Neer’s classification prognosticate the outcome. 
Внутренний маркетинг как инструмент повышения эффективности интеллектуального потенциала вуза
Authors: Селянская Галина Николаевна
Published: October 2016

Статья посвящена проблемам формирования инновационной системы управления интеллектуальным потенциалом вуза на основе современных теоретических подходов в области менеджмента и маркетинга. Показана взаимосвязь между устойчивым развитием вуза, обеспечением устойчивой конкурентной позиции на рынке научно-образовательных услуг и его интеллектуальным потенциалом, а также необходимость ориентации вуза на развитие интеллектуального потенциала научно-педагогических работников и подготовку инновационно-мыслящих, креативных выпускников, в целях скорейшего обеспечения перехода российской экономики на новый технологический уклад. Представлены формализованное описание задачи управления интеллектуальным потенциалом вуза и обобщенная модель развития интеллектуального потенциала вуза. Описана роль внутреннего маркетинга в решении задачи активизации кадрового потенциала вуза и, как следствие, – повышения качества интеллектуального потенциала вуза и результативности его использования. Предложены стратегические мероприятия для создания новой среды реализации научно-образовательного процесса и формирования инновационной предпринимательской корпоративной культуры вуза. Описаны возможные изменения в организационной структуре вуза для поддержки предлагаемых инноваций. Статья подготовлена в рамках выполнения государственного задания Минобрнауки России № 2014/162. Тема НИР: «Конкурентоспособность российских университетов в условиях глобализации образовательного пространства».
Когнитивный метод экспертного сравнения потребительских качеств конкурирующих продуктов
Authors: Мосейко Виктор Олегович , Коробов Сергей Александрович , Тарасов Алексей Викторович
Published: October 2016

Предлагаемая статья посвящена методическому обеспечению экспертного сравнения потребительских качеств конкурирующих продуктов. Для реализации данного метода используется ресурсный подход, основанный на том, что потребительские качества сравниваемых продуктов определяются способностью этих продуктов в разной мере обеспечивать взаимное влияние ресурсов в процессе производства новых продуктов. Для проведения сравнительного анализа качественных параметров предлагается экспертный подход, что обусловлено трудностью структурирования и формализации подобных задач. Итогом сравнения потребительских качеств конкурирующих продуктов являются балльные значения степени влияния, которое оказывает каждый из шести используемых ресурсов (человеческий, технический, материальный, организационный, информационный, институциональный) на освоение всех ресурсов в процессе производства нового продукта, для случаев применения в этом процессе каждого из сравниваемых продуктов.
Fornecimento de café na Universidade Federal do Rio Grande do Norte: uma análise de custos e opções
Authors: Lima Victor Godeiro de Medeiros
Published: October 2016

Esse estudo buscar mensurar quais são os gastos com o fornecimento de café por parte da Universidade Federal do Rio Grande do Norte - UFRN. Para tanto, obteu-se os dados com o Departamento de Material e Patrimônio e o Setor de Administração de Contratos da UFRN. Além disso, comparou-se esse tipo de fornecimento com outros possíveis para considerar qual seria o menos custoso para os cofres públicos. Percebeu-se que o preparo de café solúvel em vez de café coado seria menos custoso para a universidade, fato esse que, se fosse concretizado, reduziria o gasto com o fornecimento de café em mais de 40%. Constatou-se que os gastos para fornecer café em 2013 foram próximos de R$ 1.000.000,00. Logo, a importância do trabalho reside na conscientização da população a respeito dos gastos dos órgãos públicos.
Jogo de planilhas: o desafio de Alice
Authors: Mendes Abreu de Melo Diego Felipe
Published: October 2016

A hipótese da Rainha Vermelha prevê que num sistema evolutivo, é necessário contínuo desenvolvimento para manter a aptidão quanto aos sistemas com que se está coevoluindo. Baseando-se numa proposta de reinterpretação do atual contexto sociopolítico brasileiro mediante transposição da hipótese da Rainha Vermelha, este artigo visa: analisar criticamente a jurisprudência, a doutrina e o direito positivo atuais frente ao jogo de planilha; apresentar as principais discussões doutrinárias, as soluções propostas pelos tribunais de contas e a tratativa do assunto frente à mudança de paradigma na administração pública bem como na accountability democrática. Este estudo demonstra antijuridicidade do jogo de planilhas analisando os princípios gerais do direito, a Constituição da República e a tipificação da prática, na legislação infraconstitucional, como ilícito administrativo, civil, penal e “de improbidade”. Para coibir a prática, o Tribunal de Contas da União, em menos de um mês, editou quatro súmulas ligadas ao jogo de planilhas. O Tribunal de Contas mineiro ainda não estabeleceu política de fiscalização com foco em detecção de jogo de planilhas, embora seja pioneiro no desenvolvimento de sistemas de cruzamentos de malhas eletrônicas de dados. Cessar a coevolução da hipótese da Rainha Vermelha só é possível se uma das espécies da relação evolutiva tiver sua aptidão muito reduzida ou for extinta. As soluções propostas envolvem medidas paliativas em curto prazo e outras, dotadas de maior definitividade e efetividade, como incentivo à accountability democrática, uso de atividades de inteligência, maior transparência na execução de despesas públicas e educação fiscal, reduzindo a opacidade do poder.
In Dairy Cows with Clinical Mastitis Do Systemic Antimicrobials in Addition to Intramammary Antimicrobials Improve Clinical Cure Rates Compared to Intramammary Antimicrobials Only?
Authors: Barden Matthew
Published: October 2016

Clinical bottom line

In spite of limitations to the available studies, in cattle with clinical mastitis and an absence of systemic signs there is no evidence that combined systemic and intramammary antimicrobial therapy improves clinical cure rates compared to intramammary antimicrobial therapy only.

In two studies, cattle with severe coliform mastitis showed improved clinical parameters following combined systemic and intramammary antimicrobial therapy compared to intramammary antimicrobial therapy only.
Etude des résidus de simazine dans les vignobles et de leur action sur la vigne
Authors: Nikov M. , Koltcheva B. , Atanassova D.
Published: October 2016

La simazine est généralement retenue dans la couche superficielle du sol. ElIe ne s'accumule pas, car elle est dégradée. ElIe entraîne une modification du nombre et des proportions relatives des micro-organismes du sol. L'ammonification et la nitrification deviennent plus intense et il en résulte une augmentation du coefficient de fertilité et des rendements.

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Simazine is generally retained in the uppermost soil layer. As it is degraded, there is no accumulation. The number and relative proportions of soil microbes are modified by simazine. Ammonification and nitrification are promoted resulting in an increase in the soil fertility and vegetal production.
Statistical Downscaling to Predict Monthly Rainfall Using Generalized Linear Model with Gamma Distribution
Authors: Soleh Agus M
Published: October 2016

Statistical Downscaling (SDS) models might involve ill-conditioned covariates (large dimension and high correlation/multicollinear). This problem could be solved by a variable selection technique using L1 regularization/LASSO or a dimension reduction approach using principal component analysis (PCA). In this paper, both methods were applied to generalized linear modeling with gamma distribution and compared to predict rainfall models at 11 rain posts in Indramayu. More over, generalized linear model with gamma distribution was used to obtain non-negative rainfall prediction and compared with principal component regression (PCR). Two types of ill-conditioned data with different characteristics (CMIP5 and GPCP version 2.2) were used as covariates in SDS modeling. The results show that three methods (PCR, Gamma-PC, and Gamma-L1) did not demonstrate significant difference in term of Root Mean Square Error (RMSE) after addition of dummy variables (month) in the models. However, a generalized linear modeling with gamma distribution could be considered as the best methods since it provided non-negative rainfall predictions.