bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunohistochemical expression in idiopathic inflammatory myopathies at a single center in Vietnam
Authors: Ngo Dat Quoc , Le Si Tri , Phan Khanh Hoang Phuong , Doan Thao Thi Phuong , Nguyen Linh Ngoc Khanh , Dang Minh Hoang , Ly Thien Thanh , Phan Thu Dang Anh
Published: June 2024

Background: The identification of idiopathic inflammatory myopathies (IIMs) requires a comprehensive analysis involving clinical manifestations and histological findings. This study aims to provide insights into the histopathological and immunohistochemical aspects of IIMs. Methods: This retrospective case series involved 56 patients diagnosed with IIMs at the Department of Pathology, University of Medicine and Pharmacy at Ho Chi Minh City, from 2019 to 2023. The histology and immunohistochemical expression of HLA-ABC, HLA-DR, C5b-9, Mx1/2/3, and p62 were detected. Results: We examined six categories of inflammatory myopathy, including immunemediated necrotizing myopathy (58.9%), dermatomyositis (DM; 23.2%), overlap myositis (8.9%), antisynthetase syndrome (5.4%), inclusion body myositis (IBM; 1.8%), and polymyositis (1.8%). The average age of the patients was 49.7 ± 16.1 years, with a female-to-male ratio of 3:1. Inflammatory cell infiltration in the endomysium was present in 62.5% of cases, perifascicular atrophy was found in 17.8%, and fiber necrosis was observed in 42 cases (75.0%). Rimmed vacuoles were present in 100% of cases in the IBM group. Immunohistochemistry showed the following positivity rates: HLA-ABC (89.2%), HLA-DR (19.6%), C5b-9 (57.1%), and Mx1/2/3 (10.7%). Mx1/2/3 expression was high in DM cases. p62 vacuole deposits were noted in the IBM case. The combination of membrane attack complex and major histocompatibility complex I helped detect IIMs in 96% of cases. Conclusions: The diagnosis of IIMs and their subtypes should be based on clinical features and histopathological characteristics. Immunohistochemistry plays a crucial role in the diagnosis and differentiation of these subgroups.
Establishing delivery route-dependent safety and efficacy of living biodrug mesenchymal stem cells in heart failure patients
Authors: Jihwaprani Muhammad Candragupta , Sula Idris , Charbat Mohamed Ahmed , Haider Khawaja Husnain
Published: June 2024

BACKGROUND

Mesenchymal stem cells (MSCs) as living biopharmaceuticals with unique properties, i.e. , stemness, viability, phenotypes, paracrine activity, etc. , need to be administered such that they reach the target site, maintaining these properties unchanged and are retained at the injury site to participate in the repair process. Route of delivery (RoD) remains one of the critical determinants of safety and efficacy. This study elucidates the safety and effectiveness of different RoDs of MSC treatment in heart failure (HF) based on phase II randomized clinical trials (RCTs). We hypothesize that the RoD modulates the safety and efficacy of MSC-based therapy and determines the outcome of the intervention.

AIM

To investigate the effect of RoD of MSCs on safety and efficacy in HF patients.

METHODS

RCTs were retrieved from six databases. Safety endpoints included mortality and serious adverse events (SAEs), while efficacy outcomes encompassed changes in left ventricular ejection fraction (LVEF), 6-minute walk distance (6MWD), and pro-B-type natriuretic peptide (pro-BNP). Subgroup analyses on RoD were performed for all study endpoints.

RESULTS

Twelve RCTs were included. Overall, MSC therapy demonstrated a significant decrease in mortality [relative risk (RR): 0.55, 95% confidence interval (95%CI): 0.33-0.92, P = 0.02] compared to control, while SAE outcomes showed no significant difference (RR: 0.84, 95%CI: 0.66-1.05, P = 0.11). RoD subgroup analysis revealed a significant difference in SAE among the transendocardial (TESI) injection subgroup (RR = 0.71, 95%CI: 0.54-0.95, P = 0.04). The pooled weighted mean difference (WMD) demonstrated an overall significant improvement of LVEF by 2.44% (WMD: 2.44%, 95%CI: 0.80-4.29, P value ≤ 0.001), with only intracoronary (IC) subgroup showing significant improvement (WMD: 7.26%, 95%CI: 5.61-8.92, P ≤ 0.001). Furthermore, the IC delivery route significantly improved 6MWD by 115 m (WMD = 114.99 m, 95%CI: 91.48-138.50), respectively. In biochemical efficacy outcomes, only the IC subgroup showed a significant reduction in pro-BNP by -860.64 pg/mL (WMD: -860.64 pg/Ml, 95%CI: -944.02 to -777.26, P = 0.001).

CONCLUSION

Our study concluded that all delivery methods of MSC-based therapy are safe. Despite the overall benefits in efficacy, the TESI and IC routes provided better outcomes than other methods. Larger-scale trials are warranted before implementing MSC-based therapy in routine clinical practice.
THE POSITIVE EFFECTS OF GLOBAL PARTNERSHIP FOR MUTUAL LEARNING: THE GAMBIA – UK PARTNERSHIP
Authors: Sidibeh Lamin
Published: June 2024

An important inspiration for this research desired from the over-riding Colonial discourse in policy documents which promote intercultural learning and global citizenship as against discourses hidden under a rhetoric which focuses on liberal ideals of common humanity and celebrations of diversity. The research design has been informed by a number of theoretical perspectives with a view to the principle of reciprocity mutuality and equality in north/south teacher study visits. It is argued that before global citizenship can achieve the goals of social and ecological justice, teachers need to examine critically their won assumptions/and perceptions of other cultures and the world. As suggested by the post-colonial theory, development was never designed to deal with humanitarian and environmental problems but simply a way to perpetuate the dominance of the western countries and cultures with their high standards of living. The research approach was at two levels: the more strategic level which mainly targets officials of the National Environment Agency (NEA) of the Gambia, and the school level was to examine how the UK – Gambia Partnership had developed and it provided the study visit courses for both the UK Gambian teachers to learn from them. Collected data revealed that the NEA/Tide Partnership had promoted and motivated reflective engagements of both the UK and Gambian participants through the study visit courses, thus enhancing mutual understanding and respect. These benefits were expressed by the participants particularly with regards to increasing knowledge in sustainable development education, in intercultural understanding and in their professional practices.
GREEN STIMULUS: DRIVING PUBLIC INVESTMENTS TOWARDS A SUSTAINABLE FUTURE FOR ALL
Authors: Mohan Pravansh
Published: June 2024

There has been a renewed vigour for governments across the world to drive public investments towards a path of economic recovery that is sustainable and tackles the looming effects of climate change. Research shows that public investments have a large potential for financing green initiatives and provide incentives across the value chain. In countries like India and other developing countries, public investment has proven to be successful in encouraging sustainable development and conservation of resources, as well as increasing the use of green technologies and renewable energy. However, there are limitations to the extent that public financing can achieve the sustainable goals that are required for lasting social, economic, and environmental impact. This paper examines the benefits of public investment and adopts a critical approach to examine the pitfalls that currently exist within the system of green financing. This paper further explores opportunities for multi sectoral collaboration, and advocates for the creation of a holistic investment environment. The paper poses policy recommendations for future research in the field, emphasizing the need for better data collection, creation of targeted budgets, and capacity building to improve efficiencies.
EXPLICATING MARKOV CHAINS AND TRANSITION PROBABILITY MATRICES VIA SIMPLE BOARD GAMES
Authors: Verma Kkhushi
Published: June 2024

A fairly common, and simple, way to statistically model random and stochastic processes is Markov chains. They have been applied to a wide variety of fields, like text generation, financial modelling, production, linguistics, marketing, computer science, and Signal Processing[1]. Simple board games can be used to illustrate its fundamental concepts, as in many popular board games, probabilistic reasoning plays a crucial role. For example, in Monopoly, which is a looping board game that consists of all recurrent states, for imperative purposes, the primary quantity of interest is the probability of being on any of the 40 positions in a specific turn. Ash and Bishop [3], determined the steady state probability of a player landing on any Monopoly square under the assumption that if a player goes to jail, he or she stays there until the Monopoly player rolls doubles or has spent three turns in jail. This model leads to an extremely practical observation for people who play the game often. [1]. In another chance based board game like Snakes & Ladders, games where players win by reaching a final square which consists of all transient states excluding the recurring ending state, players are interested in the probability of finishing the game in certain moves. Thus, understanding of mathematical model behind these games becomes quite crucial and significant in terms of game design, since any modification in rules and parameters could change the whole occurrence. This paper explores a method to analyse the prototype of chance based simple board games, depicting the application of Markov chain and using these as a basis to further indicate how complex games can be tackled.
On the Local Extension of the Group of Parallel Translations in Three-Dimensional Space. II
Authors: Кыров В.А.
Published: June 2024

{В данной статье решается проблема локального расширения группы параллельных переносов трехмерного пространства до локально ограниченно точно дважды транзитивной группы Ли преобразований того же пространства. Локально ограниченно точная дважды транзитность означает существование единственного преобразования, которое переводит произвольную пару несовпадающих точек из некоторой открытой окрестности почти в любую пару точек из той же окрестности. Поставленная задача решается для четырех случаев, связанных с жордановыми формами матриц третьего порядка. С помощью этих жордановых матриц записываются системы линейных дифференциальных уравнений, решения которых приводят к базисным операторам шестимерного линейные пространства. Требуя замкнутости коммутаторов базисных операторов, находим алгебры~Ли. Проверяя условие ограниченно точной дважды транзитивности, получаем алгебры~Ли искомых групп Ли преобразований. В конце работы доказывается, что эти алгебры Ли либо разрешимы, либо представимы в виде прямой суммы разрешимого идеала и подалгебры, изоморфной $sl(2,R)$. При этом разрешимые алгебры Ли разлагаются в прямую суммы нильпотентного идеала и разрешимой подалгебры. В конце устанавливается изоморфизм некоторых алгебр Ли из числа найденных выше.
Обратная коэффициентная задача для двумерного волнового уравнения с начальными и нелокальными граничными условиями
Authors: Durdiev D. K. , Suyarov T.R.
Published: June 2024

In this paper, we consider direct and inverse problems for the two-dimensional wave equation. The direct problem is an initial boundary value problem for this equation with nonlocal boundary conditions. In the inverse problem, it is required to find the time-variable coefficient at the lower term of the equation. The classical solution of the direct problem is presented in the form of a biorthogonal series in eigenvalues and associated functions, and the uniqueness and stability of this solution are proven. For solution to the inverse problem, theorems of existence in local, uniqueness in global, and an estimate of conditional stability are obtained. The problems of determining the right-hand sides and variable coefficients at the lower terms from initial boundary value problems for second-order linear partial differential equations with local boundary conditions have been studied by many authors. Since the nonlinearity is convolutional, the unique solvability theorems in them are proven in a global sense. In the works, the method of separation of variables is used to find the classical solution of the direct problem in the form of a biorthogonal series in terms of eigenfunctions and associated functions. The nonlocal integral condition is used as the overdetermination condition with respect to the solution of the direct problem. The direct problem reduces to equivalent integral equations of the Fourier method. To establish integral inequalities, the generalized Gronwall-Bellman inequality is used. We obtain an a priori estimate of the solution in terms of an unknown coefficient, that are useful for studying the inverse problem.
On Some Properties of Strong Oscillation Exponents of Solutions of Linear Homogeneous Differential Equations
Authors: Сташ А.Х.
Published: June 2024

Тематика исследования данной работы находится на стыке теории показателей Ляпунова и теории колеблемости. В работе исследуются различные разновидности показателей колеблемости (верхние или нижние, сильные или слабые) строгих знаков, нестрогих знаков, нулей, корней и гиперкорней ненулевых решений линейных однородных дифференциальных уравнений с непрерывными на положительной полуоси коэффициентами. В первой части настоящей работы построен пример линейного однородного дифференциального уравнения порядка выше второго, спектры верхних сильных показателей колеблемости строгих знаков, нулей и корней которого совпадают с заданным суслинским множеством неотрицательной полуоси расширенной числовой прямой, содержащим нуль. При этом все перечисленные показатели колеблемости на множестве решений построенного уравнения являются абсолютными. При построении указанного уравнения использованы аналитические методы качественной теории дифференциальных уравнений, в частности, авторская методика управления фундаментальной системой решений таких уравнений в одном частном случае. Во второй части работы доказано, что на множестве решений уравнений порядка выше второго сильные показатели колеблемости нестрогих знаков, нулей, корней и гиперкорней не обладают свойством остаточности. В качестве следствия выводится существование функции из указанного множества, обладающей следующими свойствами: все перечисленные показатели колеблемости являются точными, но не абсолютными. При этом все сильные показатели, как и все слабые, равны между собой.
La ética en la era digital
Authors: Arriola Rosales Carla Rossana
Published: June 2024

PROBLEMA: Se plantea que mientras la tecnología avanza a un ritmo vertiginoso, la evolución dé normativas éticas y legales es mucho más lenta. OBJETIVO: Establecer un marco ético que pueda adaptarse y responder a los rápidos cambios tecnológicos, protegiendo así los valores humanos fundamentales y promoviendo un uso responsable de la tecnología. MÉTODO: El estudio adoptó un enfoque postpositivista y se llevó a cabo mediante métodos mixtos descriptivos. Se aplicó una encuesta a una muestra de 26 usuarios, y los datos recopilados fueron analizados estadísticamente para verificar su uso.  RESULTADOS: Los resultados indicaron que el 26% de los encuestados considera que la ética digital es importante en la era de la tecnología, y este promueve proporcionar acceso universal a la información. Además, el 53.8% consideró que estas bibliotecas ayudan a buscar información éticamente. El 53.9% afirmó que la ética digital es esencial para la construcción de una ciudadanía digital responsable que fomenta la responsabilidad en línea. CONCLUSIÓN: La ética digital facilita el acceso universal a la información y promover prácticas éticas en la búsqueda y el uso de información en línea lo cual previene la desinformación.
The Use of Artificial Intelligence in Physiotherapy
Authors: Tüfekçi Bengisu
Published: June 2024

Considering the advantages such as customizing parameters such as time, intensity, difficulty, speed suitable for the patient level, enriching treatment programs, reducing the possible burnout of the patient and therapist during the rehabilitation process, and increasing motivation, artificial intelligence within the scope of physiotherapy rehabilitation services will increase the quality of rehabilitation services and provide cost-effective results in the long term.
The Rise of the Machines: Artificial Intelligence in Ophthalmology - A Boon or Bane?
Authors: Yılmaz İbrahim Edhem
Published: June 2024

Ophthalmology, the medical field dedicated to eye care, is undergoing a transformation due to the advent of artificial intelligence (AI). This review article explores the growing use of AI in ophthalmic practices, focusing on disease diagnosis, screening, and surgical guidance. We examine the potential benefits of AI-powered tools, including their ability to improve the accuracy, efficiency, and accessibility of eye care. However, we also acknowledge the ethical and practical challenges associated with this technology, such as algorithmic bias, the lack of explainability, and potential job displacement. We envision a future where ophthalmologists and AI collaborate to improve patient care and usher in a new era of ophthalmic practice.
Artificial Intelligence and Microbiology
Authors: Kandilci Mert , Yakıcı Gülfer , Kayar Mediha Begüm
Published: June 2024

The concept of Artificial Intelligence (AI) is increasingly important in the healthcare sector today. Components of AI such as machine learning and deep learning are being utilized in various applications within the field of microbiology. This study examines the uses of AI in microbiology and its role in healthcare applications.
Machine learning enables computer systems to analyze data using algorithms that mimic human intelligence, while deep learning processes information through multi-layered artificial neural networks. These technologies are used in many areas such as microbiological diagnosis, drug discovery, infection control, and patient monitoring.
For instance, AI-supported systems are used in microbiological diagnosis to shorten diagnosis times and increase accuracy compared to traditional methods. Additionally, smart systems developed for preventing hospital-acquired infections alert hospital staff, thus reducing the risk of infection.
AI also plays a significant role in the diagnosis of microorganisms such as viruses and fungi. Especially, AI-supported image analysis methods are utilized for rapid and accurate diagnosis. However, there are some challenges in the use of AI. Issues related to data privacy and ethics are among the factors limiting the applications of AI in microbiology and healthcare. Furthermore, the cost and complexity of algorithm implementation pose additional challenges.
By discussing the applications of AI in microbiology and its potential in the future, this study sheds light on innovative developments in the healthcare sector.
Sistemas digitales del pasado al presente y su relación con la educación superior
Authors: Andaluz Guzmán José Francisco
Published: June 2024

PROBLEMA: se percibe en la enseñanza de sistemas digitales que los programas de estudio no responden a los avances tecnológicos de la sociedad actual, asimismo el crecimiento de estos avances es mucho más rápido que la enseñanza recibida por los profesionales de las ingenierías que imparten la catedra de sistemas digitales. OBJETIVO: describir la evolución de la electrónica digital desde sus primeras aplicaciones en el mundo hasta el año 2023, y su relación con la enseñanza de las universidades de San Carlos en Guatemala (USAC) y la Universidad de EL Salvador (UES). MÉTODO: se realizó una investigación bibliográfica sobre sistemas digitales tomando en cuenta los programas de estudio de la USAC y de la UES desde la perspectiva de autores de sistemas digitales y una entrevista semiestructurada a 5 docentes que trabajan con esta temática. RESULTADOS: los avances tecnológicos no están en sintonía con la enseñanza universitaria. Los programas de estudio de la USAC y de la UES deben ser actualizados con más frecuencia para disminuir la brecha entre lo aprendido por alumnos y el desarrollo electrónico mundial. CONCLUSIÓN: es necesario que las universidades USAC y UES fortalezcan sus programas de enseñanza para que sus alumnos puedan recibir teoría de acuerdo con las necesidades.
Devlet Parasız Yurtlarında Kalan Ortaöğretim Öğrencilerinin Yurt Yaşantılarına İlişkin Görüşlerinin İncelenmesi
Authors: Yavrutürk Ali Rıza
Published: June 2024

Bu araştırmanın amacı, devlet parasız yurtlarında kalan ortaöğretim öğrencilerinin yurt yaşantılarına ilişkin görüşlerinin incelenmesidir. Araştırmanın çalışma grubunu 2022-2023 eğitim öğretim yılında Orta Karadeniz Bölgesi’nde yer alan bir ilçede devlet parasız yatılı yurtlarında kalan 14 ortaöğretim öğrencisi oluşturmaktadır. Çalışma grubu amaçlı örnekleme yöntemlerinden biri olan kolay ulaşılabilir örnekleme yöntemi ile seçilmiştir. Çalışma grubunda cinsiyet, okul türü, sınıf düzeyi açısından maksimum çeşitlilik sağlanmaya çalışılmıştır. Araştırmada nitel araştırma desenlerinden olgu bilim deseni kullanılmıştır. Araştırmanın verilerinin toplanmasında veri toplama tekniği olarak yarı yapılandırılmış görüşmelerden faydalanılmıştır. Yarı yapılandırılmış görüşmelerin içerik analizi sonucunda tema ve kodlar ortaya çıkmıştır. Araştırma sonucunda, katılımcıların yurt yaşantısını öznel yaşantılarına göre tanımladıkları görülmüştür. Yurt yaşantısında başta yalnızlık ve özlem olmak üzere farklı duyguların yoğun olarak yaşadıkları sonucuna ulaşılmıştır. Ayrıca, fiziksel yapı, güvenlik, temizlik ve beslenme ile ilgili problemler yaşadıkları ve bu problemlere karşı bazı baş etme mekanizmaları geliştirdikleri sonucuna ulaşılmıştır. Son olarak, belletici öğretmenlere, idarecilere, yurt hizmet personeli ve eğitim politika yapıcılarına bazı önerilerde bulunularak veriler alanyazı bulguları ile birlikte tartışılmıştır.
Does The Scientific Evidence Support the Idea of Promoting Sucralfate as The First Aid Topical Management for Burn Wound? A Literature Review
Authors:   Faculty of Medicine of Sriwijaya -Palembang, South Sumatera, Indonesia, Linata Angela Maria , Fawzy Ahmad ,   Department of Surgery, Faculty of Medicine University of General Soedirman –Margono Soekarjo County Hospital, Indonesia
Published: June 2024

Burn injuries, caused by heat, chemicals, radiation, or electricity, significantly impact morbidity and mortality. Sucralfate, a mucoprotective agent composed of sucrose sulfate and aluminum hydroxide, forms a protective barrier on wounds, reduces pain, stimulates healing, and has anti-inflammatory effects. By stimulating prostaglandin secretion and binding to proteins in the ulcer bed, sucralfate enhances gastrointestinal mucosa defenses and acts locally in injured tissues, minimizing systemic effects. Clinical studies demonstrate its effectiveness in improving wound healing, reducing pain, and promoting tissue regeneration, angiogenesis, and granulation tissue development in burn patients. For optimal burn wound therapy, proper patient selection, formulation techniques, and integration with standard protocols are crucial. Further large-scale randomized controlled trials are necessary to establish guidelines and expand sucralfate's clinical applications.
Assessing the Relationship between External Debt Financing and Gross Domestic Product in Ghana
Authors:   Department of Finance, Kwame Nkrumah University and Science and Technology (KNUST), Kumasi, Ghana, Gyampoh Obeng Samuel Kwaku , Delali Kornu Dr. Daniel ,   Department of Accounting, Finance and Economics Evangelical Presbyterian University College- Ho, Ghana, Dzogbede Dr. Oliver ,   Department of Accounting, Finance and Economics Evangelical Presbyterian University College- Ho, Ghana, Opokuware Dr. Emmanuel ,   Finance Directorate, University of Environment and Sustainable Development, Somanya, Ghana, Etornam Kornu Samuel ,   Universidad Empresarial de Costa Rica, Costa, Business School of Costa Rica (UNEM)
Published: June 2024

The level of external debt of a country is of fundamental importance in every economy, as external debt may reflect the effectiveness and efficiency of an economy. The study was motivated by the ever-increasing rate at which Ghana has consistently borrowed from external sources. This study aimed to assess the relationship between external debt financing and gross domestic product and establish the determinants of external debt financing in Ghana. Using selected time series data (Gross domestic product, external debt, population growth, inflation, Literacy rate, export of goods and service, general government expenditure, and interest on external debt, 1978 - 2017) based on literature reviewed on the macro economy of Ghana, the study employed Autoregressive Distributed lag model (ARDL) after the Augmented Dickey-Fuller test statistic and Philip Perron proofs not to be stationary at levels but stationary at first difference. For that matter, ARDL was used to assess the impact of external debt financing on GDP to establish the determinants of external debt. Diagnostic tests which include auto-correlation, heteroscedasticity, and normality were also performed. Based on the results of the study, it was concluded that, variables were related only in the short run but not related in the long run. It was recommended that, external borrowing, population growth, inflation, general government expenditure and literacy rate should be control since their coefficients proves to have negative impact on GDP and on external debts
The Mediation Role of E-Trust toward Perceived Reputation, Perceived Usefulness and E-Purchase Intention in Bukalapak
Authors:   Departemen of Manajemen, Faculty Economy and Business, Universitas Negeri Malang, Malang, Indonesia, Anggawi Tb. Irsyad , Fitri Raisa ,   Departemen of Manajemen, Faculty Economy and Business, Universitas Negeri Malang, Malang, Indonesia
Published: June 2024

The focus of this research is to determine the effect of perceived reputation and perceived usefulness on e-purchase intention and to determine the mediating effect of e-trust. This research used a sample of marketplace users in Indonesia with 232 respondents. Hypothesis testing uses Structural Equation Modeling - Partial Least Square (SEM-PLS) with SMART PLS 3 as the software. This research combines different research models into one model with two theoretical concepts, TRA and TAM theories with perceived reputation and perceived usefulness variables as independent variables in the research. This research found that perceived reputation and perceived usefulness have a significant effect on e-purchase intention. However, e-trust does not mediate the effect between perceived reputation and perceived usefulness on e-purchase intention.
Analysis Dimensions of Globalization and Poverty : Vector Error Correction Model (VECM) Approach
Authors:   Master of Economic, Faculty of Economic and Business, University of Lampung, Bandar Lampung, 35141, Indonesia., Nindien Qurrota Ayu , Yulihar Taher , Arivina Ratih ,   Lecturer of Economics, Faculty of Economic and Business, University of Lampung, Bandar Lampung, 35141, Indonesia, Murwiati Asih ,   Lecturer of Economics, Faculty of Economic and Business, University of Lampung, Bandar Lampung, 35141, Indonesia, Suparta I Wayan ,   Lecturer of Economics, Faculty of Economic and Business, University of Lampung, Bandar Lampung, 35141, Indonesia, Aida Neli ,   Lecturer of Economics, Faculty of Economic and Business, University of Lampung, Bandar Lampung, 35141, Indonesia
Published: June 2024

This study analyzes how the dimensions of globalization, economic growth, and income inequality affect poverty with the Vector Error Correction Model (VECM) model in the long term. This research method uses time series data and secondary data. The data used in this study are economic growth rate, Gini ratio index, de facto and de jure economic globalization index, social globalization index (%), and the number of poor people (%) in Indonesia from 1984 to 2020 sourced from BPS, World Bank, and KOF ETH Zurich. The result of this study is the cointegration of the dependent variable, namely poverty, with the independent variables, namely the dimensions of globalization, economic growth, and inequality in Indonesia. Hence, the model chosen in this study is the Vector Error Correction Model (VECM). Economic growth, economic globalization, social globalization, and economic cooperation negatively and significantly affect poverty in Indonesia in the long run. Inequality has a positive and significant effect on poverty in Indonesia in the long run.
The Effect of Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR) and Non-Performing Loan (NPL) Against Return on Asset (ROA) With Net Interest Margin (NIM) as an Intervening Variable in BUMN Bank Listed on the Indonesia Stock Exchange 2018-2022
Authors:   Student, Faculty of Economics, Gunadarma University, West Java, Indonesia, Firanti Noor Gusti Maya , Susy Suhendra Euphrasia ,   Lecturer, Faculty of Economics, Gunadarma University, West Java, Indonesia
Published: June 2024

This study aims to determine the effect of Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR) and Non- Performing Loan (NPL) in the Return on Asset (ROA) with Net Interest Margin (NIM) as an Intervening Variable in BUMN Bank Listed on the Indonesia Stock Exchange 2018-2022. The independent variable used in this study is Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR) and Non-Performing Loan (NPL). The dependent variable used is Return On Asset (ROA). The intervening variable used is Net Interest Margin (NIM). The method used in this study uses nonprobability sampling technique, using secondary and quantitative data. The analysis technique in this research uses Smart PLS 3.0 by analysing the inner model such as the coefficient of determination, hypothesis testing and path analysing. The research show that, CAR has a significant and positive effect on NIM, LDR and NPL have no significant and unidirectional effect on NIM, CAR and LDR have no significant and unidirectional effect on ROA, NPL and NIM have a significant and unidirectional effect on ROA, NIM can mediate the influence of the variable CAR on ROA, NIM cannot mediate the influence of the LDR and NPL variables on ROA.
Examining the Interplay of Consumer Behavior and Local Community Engagement in the Success of OCOP Initiatives: A Case Study of Nghe an Province, Vietnam
Authors:   Phan Boi Chau School for the gifted, Bao Chau Phan Thi
Published: June 2024

This study explores the influence of consumer behavior and community engagement on the success of One Commune One Product (OCOP) initiatives in Nghe An Province, Vietnam, while also investigating the moderating effect of brand awareness. Drawing upon the Theory of Planned Behavior, Social Capital Theory, and brand equity frameworks, a conceptual model was developed and tested using structural equation modeling (SEM) with data from 285 OCOP enterprises, cooperatives, and household businesses. The results indicate that consumer behavior and community engagement have significant positive impacts on the success of OCOP initiatives, with brand awareness positively affecting consumer behavior and moderating the relationship between consumer behavior and OCOP success. This study contributes to the theoretical understanding of rural development by showcasing the interplay of consumer, community, and brand factors in determining OCOP outcomes. Practical implications for policymakers and OCOP stakeholders are discussed, underlining the significance of consumer-oriented product development, community engagement mechanisms, and effective branding strategies. Despite its limitations, this research offers valuable insights for designing and implementing sustainable rural development programs in Vietnam and beyond.
Psychosocial Determinants of Bad Quality of Life Among People Living with HIV/AIDS on Antiretroviral Drugs in Kinshasa /DR Congo
Authors:   Faculty of Medicine, Simon Kimbangu University (USK), Kinshasa, Democratic Republic of Congo, Pila Justin Muilu , Natuhoyila Aliocha Nkodila ,   School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo, Masika Yvonne Duagani ,   Department of Psychology, Faculty of Psychology and Educational Sciences, University of Kinshasa (UNIKIN), Republic of Congo
Published: June 2024

Context and Objective: The search for psychosocial determinants of bad quality of life (Qol) in people living with the human immunodeficiency virus (PLWHA) under Highly active antiretroviral therapy (HAART) constitutes a real public health problem in Kinshasa. Determine the psychosocial factors of bad Qol among PLWHA on antiretrovirals in Kinshasa. Methods: This was a case control study carried out in Kinshasa from January 15 to April 15, 2021, which included 1082 subjects divided into two groups including 541 PLWHA patients and 541 no-PLWHA. Sampling was non-probability based on matching patients from case to control. Recruitment was carried out first among PLWHA, then matching was done by age and sex considering the sample of PLWHA. The variables of interest were sociodemographic, condom use, psychoactive substance abuse, perceived stress, anxiety-depression, and bad Qol. Results: The average age of PLWHA was 50.4±10.7 years with a sex ratio of 2.81. A third of PLWHA (32.9%) were married (p<0,001), 9.2% used condoms (p<0,001), 68% had a secondary education (p=0,006), 54.3% had an occupation (p=0,005), 54.2% attended independent churches (p=0,033), 52.1% had an average socioeconomic level (p<0,001), 12.2% consumed alcohol (p<0,001), 15.3% had a bad Qol. The main determinants of bad quality of life were stage 4 (ORa : 3,06 IC95% : 1,47-7,79), side effects due to HAART (ORa : 1,90 IC95% : 1,04-3,60), perceived stress (ORa : 4,14 IC95% : 1,32-12,94) and anxiety-depression (ORa : 6,88 IC95% : 1,60-9,43). Conclusion: Bad quality of life is present among PLWHA in Kinshasa. It was linked to stage 4, side effects due to Highly active antiretroviral therapy, perceived stress, anxiety-depression in HIV-positive people.
Design and Implementation of Socialization Assistance Device for the Deaf-Blind Community
Authors: Meenakshi Sudhish  , Nehna Lezya Sarin M  , Sandra Gopakumar  , Sheeba Babu  , Beena A O
Published: June 2024

Deaf-blind people face major communication issues due to a lack of appropriate technology. Our system, a braille device designed specifically for the deaf-blind, provides a solution to the problem by allowing users to feel and interpret each letter by touch in real-time, enabling smooth conversation. They can understand messages and interact meaningfully with this tactile interface, thereby overcoming the communication gap. The innovation allows deaf-blind people to participate more completely in social interactions and access information independently, improving their quality of life and promoting inclusion.
LOCALIZATION PECULIARITIES IN VIDEOGAME PLACE NAMES AND ANTHROPONYMS TRANSLATION
Authors: Babaev Anar M. , Pitina Svetlana A.
Published: June 2024

Place names and anthroponyms translation in fantasy videogames is important in the process of the game space localization and cultural adaptation. 500 place names and 500 anthroponyms and their translation into Russian are analyzed on the material of three fantasy videogames. The main translation transformations of place names include calquing, transliteration and transcribing. The most frequently used means of localizing anthroponyms in videogames include transliteration, transcribing and calquing. Both national and cultural peculiarities of the original proper name can be preserved in translation and cultural adaptation can be used for the better videogame space perception. Translation misrepresentations in transcribing and transliterating place names are analyzed, the main groups of anthroponyms translated by calquing are specified.
SPIRITUALITY AS A CRITERION OF SOCIO-PSYCHOLOGICAL NORM: THEORETICAL AND EMPIRICAL EXPERIENCE OF JUSTIFICATION FOR THE PERIOD OF LIMINALITY (INDIVIDUALS AND GROUP LEVEL)
Authors: Aksenovskaya Lyudmila N.
Published: June 2024

The article presents the results of the fi rst domestic socio-psychological empirical pilot study of the phenomenon of spirituality based on the theoretical ideas of S. L. Frank. The theoretical part of the article presents a four-aspect model of spirituality (moral, cognitive, aesthetic, religious aspects) and a six-factor model of the moral aspect (in terms of a morally perfect attitude towards another person), built on the basis of the model-forming parameter «morally perfect attitude». The criteria for socio-psychological norm and pathology are discussed. In the empirical part, with the help of a developed questionnaire, ideas about a morally perfect attitude towards another person are studied. The questionnaire was tested on a small sample of students in order to test its capabilities for studying the moral aspect of spirituality and assessing socio-psychological norms and pathologies. Conclusions are drawn about the acceptability of the developed conceptual and logical research scheme and the questionnaire used, as well as the advisability of continuing this research in terms of three other aspects of spirituality. The substantive results of the study are of an auxiliary nature due to the statistically insignifi cant sample (35 people). At the same time, the applied method of assessing the socio-psychological norm and pathology on the test sample showed a discrepancy between the results and the norm in terms of the moral aspect of the spirituality of the group.
MAXIMAL TEMPERATURES OF GAS, POROUS MEDIUM AND VELOCITY OF STATIONARY WAVE OF FILTRATION COMBUSTION OF HYDROGEN-AIR MIXTURE IN THE PRESENCE OF HEAT LOSSES
Authors: Kabilov M.M. , Sadriddinov P.B. , Shermatova Z.B.
Published: June 2024

The results of the theoretical study of the maximum temperature of gas, porous medium and speed of the stationary wave of filtration combustion of hydrogen-air mixture under heat losses are presented. The study of the above-mentioned parameters was carried out both on the basis of the numerical method of solving the system of differential equations describing the stationary mode of wave propagation, and with the help of analytical dependences derived by considering the equivalent mathematical model of FCG in the presence of heat losses. Identity of the values of the stationary wave velocity calculated by the formula and numerical Runge - Kutta method for different compositions and speed of mixture blowing gives a basis for the reliability of the results of the study. The results of the analysis of numerical calculation of temperatures distribution in the combustion wave show that at relatively small diameters of porous medium particles, less than 1 mm, and blowing velocity up to 5 m/s temperature profiles of porous medium and gas mixture do not differ, i. e. we have the one-temperature structure of the wave. Outside these limits, the temperatures of the phases in the combustion zone are significantly different, i. e. there is a difference between the temperature maxima of the solid and gas phases.
MODELING OF AORTIC DEFORMATION IN ANEURYSM AND WALL DISSECTION
Authors: Medvedev A.E. , Erokhin A.D.
Published: June 2024

The deformations of aortic walls in case of aortic aneurysm (dilation) and aortic wall dissection are studied. Numerical calculations of the load on the aortic walls at aneurysm and aortic wall dissection are carried out. It is shown that rupture of the inner layer of the vessel leads to an increase in the stress on the outer wall of the vessel. Increasing the thickness and length of the rupture increases the stresses on the outer wall of the vessel. The presence of an aneurysm of the vessel increases the stresses compared to a vessel without an aneurysm. Splitting of the inner wall of the vessel leads to an increase in the stresses on the wall - stresses decrease with increasing rupture width for a straight vessel and increase for a vessel with an aneurysm.
“GALATIFICATION” OF WOMAN: AN EXAMPLE OF LITERARY NEOLOGISM AS A PATRIARCHAL ATTITUDE TO WOMAN
Authors: Çelik Yavuz
Published: June 2024

Throughout the centuries of patriarchal society, women have been shaped, identified and educated from a male perspective under male domination. However, in the 20th century, women began to challenge this perspective and seek their own identities. New words were introduced into literature to replace many discriminatory and degrading concepts and definitions of patriarchy against women. To introduce a new term to literature on gender, this study focuses on the derivation of a new word through neologism based on the unnamed female statue in “Pygmalion”, the well-known story of Ovid. Based on the name “Galatea” given to the female statue in the following centuries, the word “Galatification” was derived as a noun denoting the education, shaping and identification of a woman by her husband or father, making her acceptable to that man. The word was produced in accordance with the linguistic structure of English with suffixes and was presented as a verb meaning “to Galatify” and as a noun meaning “Galatification”. Furthermore, this concept, developed upon Ovid’s story, was explained practically in William Shakespeare’s famous comedy The Taming of the Shrew, written in the 1590s, through the taming of the female character Katherine by the male character Petruchio. Shakespeare used the verb “tame” in the title as a demeaning expression to imply that a woman is made acceptable to a man through transformation from a wild animal into a domestic animal. Here, Shakespeare’s character Petruchio replaces Pygmalion in Ovid, and both men sculpt and shape the woman who will enter their lives like a kind of statue, and this action can be expressed as the “Galatification of woman”.
Судебное лингвистическое исследование буллинга в трудовом коллективе
Authors: Камалходжаева Саида
Published: June 2024

В данной статье автор в рамках судебной лингвистики рассматривает буллинг в коллективе, его виды, приводя примеры некоторых языковых и неязыковых фактов психологического и иного вида насилия.
Home Remedy Practices Among Stay-at-Home COVID-19 Patients in Bangladesh
Authors: Jami Md. Abu Bakar Siddique , Islam Ritu , Sultana Rezwana , Iffat Tasnim , Jahan Mst Lubna
Published: June 2024

During the early phases of the COVID-19 pandemic, Bangladesh lacked treatments and immunizations, so patients used several home remedies to heal themselves. This study was conducted among stay-at-home COVID-19 patients in Bangladesh to determine their awareness of the disease and establish correlations between COVID-19 symptoms and the use of home remedies. This is a cross-sectional study that employed a convenient sampling technique. Primary data were collected using a convenient sampling technique from various demographic bases. Data were gathered through 70 face-to-face interviews and an online survey with 276 participants using a semi-structured questionnaire. Participants were from different regions and districts of Bangladesh. In total, 346 respondents participated in the study from May to August 2021. Nearly equal numbers of males and females of various ages participated. More than half of the participants were aged 21–30. Dhaka had the highest participation rate (82%). The study found that 95% of people were aware of the need to consult a doctor, and 99% of participants took the COVID-19 test. 46% of the participants were isolated for 1–2 weeks. Fever, dry cough, loss of smell, tiredness and fatigue, and aches and pains were the most commonly reported symptoms. 77% of the study's participants checked their O2 saturation level daily. Participants with and without various comorbid diseases used home remedies, like drinking honey-ginger tea, taking vapors or steam, eating more citrus fruits, frequent hand washing, etc. In Bangladesh, home remedies such as citrus fruits, honey-ginger tea, steam inhalation, hand washing, and mask usage were common among stay-at-home COVID-19 patients due to limited medical access. Despite seeking medical advice and testing, patients still prefer home care. This study emphasizes the need to understand these patterns and conduct further research to evaluate efficacy and inform policy development.
 
Received: 16 April 2024 | Revised: 26 May 2024 | Accepted: 17 June 2024
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
Development Of A Distance Education Experiment Set That Allows The Ratio Of Chemical Components In Hydroponic Farming Nutrient Liquid To Be Estimated By Artificial Intelligence
Authors: Yavru Celal Alp , Üncü İsmail Serkan
Published: June 2024

With the increase and development of electronic systems, especially with the advancement of artificial intelligence (AI) applications, AI has begun to meet many of humanity's needs. Due to the rapidly increasing human population and the decreasing availability of fertile land, the use of AI has become necessary in rapidly expanding soilless agriculture practices. One of the biggest challenges in soilless agriculture is the inability to accurately determine the chemical content of nutrient solutions in real-time. In this study, the results of inductively coupled plasma optical emission spectrometry (ICP-OES) and electrical conductivity (EC) were obtained for 300 hydroponic agriculture nutrient solutions containing different ratios of Mg, K, and P minerals. The obtained data were evaluated using artificial neural networks in Matlab® software, with ICP-OES results as inputs and EC results as outputs (3 inputs-1 output). The results were uploaded to the cloud system using Firebase, and an EC meter capable of communicating with the cloud was developed. The results of the produced EC meter were compared with the data in the cloud, and attempts were made to determine the element ratios in the nutrient solution content of 300 samples using artificial neural networks. The Pearson Correlation Constant (R) was found to be 0.860 for all data. According to the test results obtained with the produced system, the success rate of the artificial neural network in detecting the chemical composition of the nutrient solution ranged from 53.2% to 87.4% depending on the chemical ratios in the nutrient solution.
The role of the Environmental Education in tackling the Climate Emergency and biodiversity decline: articulating Brazilian experiences
Authors: Louro Ferreira Silva Rosana , Grandisoli Edson , Jacobi Pedro Roberto
Published: June 2024

Abstract: The transition to more sustainable societies is permeated by interests, conflicts, and predatory use of natural resources, generating vulnerability, socio-environmental injustice, and poverty. Considering that we are living in an era of uncertainty and multiplication of complex and wicked issues due to the prevailing logic of society, there is an urgent and unquestionable need to re-think educational paradigms, considering the need to redesign actions within transitional and transformational perspectives. This work describes and analyzes two educational experiences related to central and connected socio-environmental challenges: biodiversity loss and climate emergency. Both experiences encompass ways created to empower teachers to understand the complexity and create paths for action, highlighting the crucial role of participation and cooperation among different social institutions such as Governmental, Universities and NGOs. The challenge is to build communities as territory transformative agents in the use of active learning methodologies that promote meaningful knowledge from a perspective of the global South.
Key Words: Social learning. Sustainable societies. Climate schools. Teacher training.