bluuebunny/crossref_metadata_2025 huggingface dataset:
Reactive atrial-based anti-tachycardia pacing algorithm in cardiovascular implantable electronic devices is safe and feasible without increase in thromboembolic events in patients with a left atrial appendage closure device
Authors: Carter Cody , Khan Zeryab , El-Zein Rayan , Lockhart Marie , Shah Ankur , Nemer David , Tyler Jaret , Fu Eugene , Badin Auroa , Billakanty Sreedhar R. , Amin Anish K. , Chopra Nagesh
Published: October 2023

Background

Reactive atrial-based anti-tachycardia pacing (rATP) in CIED (cardiovascular implantable electronic devices) is effective in atrial fibrillation (AF) suppression. Uninterrupted systemic anticoagulation is recommended when this algorithm is activated to avoid stroke, however, the use of a rATP algorithm in patients with a left atrial appendage (LAA) closure device has not been studied. We assessed the safety and feasibility of rATP algorithm to suppress AF in patients with a LAA closure device over an extended period.

Methods

Data from 55 consecutive patients who underwent a Watchman® implant at a tertiary care hospital between September 1, 2015, and January 30, 2020, who also had an in situ Medtronic® CIED (45 with and 10 without rATP capability) were retrospectively reviewed.

Results

The 55-patient cohort was 60% male, 77 ± 8 years old, CHA2DS2-VASc score 5 (4–6), HAS-BLED score 3 (3–4), LVEF 53 ± 14%, LA size 4.4 ± 0.7 cm and ventricular pacing burden of 73 (1.4–98.3)%. The CIEDs (20 ICDs and 35 pacemakers) antedated Watchman® implants by 915 ± 725 days. Post-implant, all patients discontinued anticoagulation. Twenty patients in the rhythm-control group with active rATP algorithm displayed no increase in yearly AF burden and were less likely to develop permanent/long-standing persistent AF (p = 0.002) when compared to 35 patients in the rate-control group with CIEDs inactive/incapable of rATP over a ≤ 5-year follow-up. The longest AF episode in the rhythm-control group lasted 204 (19–2520) h. There was no increase in stroke/thromboembolism and a significant reduction in major bleeding noted over ≤ 5 years pre- versus post-implant in the whole cohort (p = 0.005).

Conclusion

rATP algorithm use is safe and feasible in patients with a Watchman® device. Patients should be forewarned of a surge in post-Watchman® implant AF burden.
Comparison of nutritional composition, bioactivities, and FTIR- ATR microstructural properties of commercially grown four mushroom species in Sri Lanka; Agaricus bisporus, Pleurotus ostreatus, Calocybe sp. (MK-white), Ganoderma lucidum
Authors: Wickramasinghe Malmi Apsara , Nadeeshani Harshani , Sewwandi Suriya Mudiyanselage , Rathnayake Isuri , Kananke Thilini Chathurangi , Liyanage Ruvini
Published: October 2023

Mushrooms have been consumed as delicacies since ancient times; however, little knowledge is available on the nutritional and bioactive properties of commercially grown mushroom species in Sri Lanka; button (Agaricus bisporus), oyster (Pleurotus ostreatus), Makandura white (Calocybe sp.), and Reishi (Ganoderma lucidum). Samples from four mushroom species were analysed for proximate composition, mineral and fatty acid content, and antioxidant, antidiabetic, and microstructural properties. Carbohydrate, protein, fat, ash, and dietary fibre content in mushroom species ranged from 64.83–79.97%, 10.53–23.29%, 0.57–4.37%, 2.80–11.00%, and 33.04 to 75.33%, respectively. The highest (P ≤ 0.05) protein and ash content were observed in A. bisporus, and G. lucidum had the highest (P ≤ 0.05) fat and dietary fibre content. When considering the micronutrients, G. lucidum comprised higher (P ≤ 0.05) Ca, Mg, Mn, and Cu, while A. bisporus had higher (P ≤ 0.05) Fe and Zn contents than other species. Essential omega-6 fatty acid, linoleic (18:2n-6) content was in the range of 37- 81% in studied mushroom samples. Results obtained from FTIR (Fourier transform infrared spectroscopy) in conjunction with ATR (Attenuated total reflectance) revealed the presence of functional groups associated with fat (̴1740 cm−1), protein (̴1560 cm−1), polysaccharides (1500–750 cm−1) and moisture (̴3300 cm−1) in mushroom samples. According to the results, P. ostreatus showed the highest (P ≤ 0.05) polysaccharide content, while G. lucidum showed the lowest (P ≤ 0.05). The highest (P ≤ 0.05) total phenolic content (TPC) (3.95 ± 0.05 mg GAE/g DW) and total flavonoid content (TFC) (2.17 ± 0.06 mg CE/g DW) were observed in P. ostreatus. Antioxidant activity measured by DPPH, ABTS, and FRAP methods was higher (P ≤ 0.05) in P. ostreatus and A. bisporus compared to the other two species. Among all the studied mushroom species, G. lucidum showed the highest (P ≤ 0.05) α-amylase (IC50 = 77.51 ± 6.80 µg/mL) and α-glucosidase (IC50 = 0.4113 ± 0.08 µg/mL) inhibition activities. This study reveals the potential of using A. bisporus, G. lucidum, and P. ostreatus for nutritional, functional, and therapeutic uses.

Graphical Abstract
Anxiety and depression among COVID-19 survivors: a cross-sectional study
Authors: Abulsaad Aya Mazen , Sonbol Hassan Mohammed , Elwasify Mahmoud Ahmed , Elboraie Osama Ahmed
Published: October 2023

Background

The novel coronavirus disease (COVID-19) outbreak has spread globally and resulted in physical suffering in addition to its negative effects on mental health. In the context of the COVID-19 pandemic, concerns about health, finances, employment, and social isolation all played a role in contributing to its effect on mental health. In this study, we aimed mainly to evaluate depression and anxiety among post-COVID-19 survivors in Egyptian population.

Results

In this study, 150 post-COVID-19 patients were included. The age range was 51.01 years ± 12.6. The prevalence of depression and anxiety were 65.3% and 36% in the COVID-19 patients 1 month after recovery. Female gender and isolation for more than 15 days are significant risk factors for depression, while age less than 50 years old, urban residence, and worry about getting infected again are significant risk factors for anxiety.

Conclusions

Based on the results, we found that COVID-19 recovered patients had a high rate of depression and anxiety. In addition to the emphasis on infection and respiratory symptoms, we need to pay more attention to post-COVID-19 psychiatric symptoms.
The association of physical activity and sedentary behaviour on health-related quality of life: a cross-sectional study from the physical activity at work (PAW) trial
Authors: Akksilp Katika , Müller-Riemenschneider Falk , Teerawattananon Yot , Chen Cynthia
Published: October 2023

Introduction

Physical inactivity and sedentary behaviour independently increase morbidity and negatively affect quality of life. This study evaluates the associations between physical activity and sedentary behaviour with health-related quality of life, including the five dimensions of quality of life (mobility, self-care, usual activities, pain or discomfort, and anxiety or depression).

Methods

This cross-sectional study analysed baseline data from Thailand's Physical Activity at Work (PAW) trial. Physical activity data were collected using the ActiGraph™ accelerometer, worn on the right hip for a minimum of three ten-hour workdays. Accelerometer data were then used to categorise participants into: (i) not-sedentary and physically active (the Reference Group), (ii) not-sedentary but inactive, (iii) sedentary but active, and (iv) sedentary and inactive. We employed the EuroQol-5 dimensions questionnaire with five scoring levels (EQ-5D-5L) to measure health-related quality of life. The Thai EQ-5D-5D valuation was utilised to convert the EQ-5D profile into utility index scores (EQ-5D values). Tobit regression models were used to analyse EQ-5D value differences. Moreover, the odds of having problems in each EQ-5D dimension were compared between categories.

Results

277 valid participant data were included. Older age (P = 0.007), higher education (P < 0.001), and higher prevalence of cardiovascular disease (P = 0.032) were observed in participants who were sedentary and physically inactive compared to other groups. We found − 0.0503 (95% CI: − 0.0946–− 0.00597) lower EQ-5D value and 1.39 (95% CI: 1.07–1.79) higher odds of reporting pain or discomfort problems in the sedentary and physically inactive group compared to the Reference Group. We also found 2.12 (95%CI: 1.14–5.40) higher odds of reporting usual activity problems in the not-sedentary but physically inactive group than in the Reference Group.

Discussion

We found further evidence of the potential benefit of higher physical activity levels and lower sedentary time for higher quality of life among healthy office workers in Thailand. Further research with larger cohorts and longitudinal data is needed to establish a stronger foundation for interventions and economic evaluations targeting physical activity promotion to improve quality of life.
Tetralogy of Fallot with restrictive ventricular septal defect by accessory tricuspid valve: repair with accessory valve preservation
Authors: Amano Kenichi , Hirata Yasutaka , Shibata Miyuki , Ono Minoru
Published: October 2023

Background

Restrictive ventricular septal defect resulting in suprasystemic right ventricular pressure is a rare entity in tetralogy of Fallot patients. It is often caused by accessory tricuspid valve tissue protruding through the defect. Surgical resection of the accessory tricuspid valve has been recommended, but the risk of tricuspid regurgitation caused by the resection has not been widely discussed.

Case presentation

A 5-month-old male who had been diagnosed with tetralogy of Fallot was referred for progressive decline in oxygen saturation. Preoperative echocardiogram revealed restrictive ventricular septal defect and severe pulmonary stenosis, suggesting suprasystemic right ventricular pressure (> 160 mmHg). Intraoperatively, accessory tricuspid valve tissue was found to be attached to the superior edge of the ventricular septal defect and partially occlude the aortic valve. The risk of tricuspid regurgitation caused by accessory tricuspid valve resection was high due to the complicated relationship between the true tricuspid valve and the accessory tricuspid valve. Therefore, the accessory tricuspid valve was preserved on the right ventricular side of the ventricular septum to avoid the risk of tricuspid regurgitation. Postoperative echocardiogram did not show tricuspid regurgitation or left ventricular outflow tract obstruction, and the patient was discharged to home on postoperative day 35 without major complications.

Conclusions

We herein reported a high-risk patient of tetralogy of Fallot with restrictive ventricular septal defect caused by accessory tricuspid valve who successfully underwent definitive repair with accessory tricuspid valve preservation considering the risk of tricuspid regurgitation.
Description of patient characteristics and medication adherence among medication access mobile application users and nonusers: a single-center questionnaire-based cross-sectional study
Authors: Assiri Ghadah , Alabdulkarim Dalal , Alanazi Asrar , Altamimi Sarah , Alanazi Nadin Lafi , Khawagi Wael
Published: October 2023

Background

In this study, we aimed to describe patient characteristics and medication adherence among medication access mobile application users and nonusers.

Methods

This was a cross-sectional study of a randomly selected sample of patients who refilled their medications either through the mobile application ‘MNG-HA Care’ or by phone call to a government-funded multispecialty hospital in Riyadh, Saudi Arabia. Data were collected through an online survey and filed either via WhatsApp or by phone call. Medication adherence was assessed using the five-item Medication Adherence Report Scale (MARS-5).

Results

A total of 280 respondents were recruited, and their mean age was 48.8 years (standard deviation (SD): 17.8). More than 75% of application users and nonusers were younger (18–64 years) and lived in urban areas, 58% were male, 37.5% held a bachelor’s degree, and 40% were unemployed. The number of respondents who accessed the mobile application (mobile application users) was 212, and 64.2% of them were adherent to their medications. Sixty-eight of the respondents used a phone call for refills (mobile application nonusers), and 77.9% of them were adherent to their medications. The most common self-reported reasons for using the application were to book an appointment and to request a medication refill. The most common self-reported reasons for not using the application were respondents’ lack of knowledge about the availability of the application and preference for speaking directly to the health care provider. Adjusted multivariate logistic regression analysis revealed that medication adherence was not associated with application use (Odds Ratio (OR): 0.65; 95% CI: 0.33–1.29). However, male patients had significantly higher adherence than females (OR 2.68, 95% CI 1.31 to 5.51), and employed patients had significantly lower adherence than unemployed patients (OR 0.37, 95% CI 0.17 to 0.81).

Conclusions

Providing patients with access to their medication list through a mobile application alone did not significantly impact medication adherence. Further research is needed to explore the potential benefits of incorporating additional features, such as medication instructions and reminders within mobile applications, to improve medication adherence.
ADAPTATION TO EX VITRO CONDITIONS OF MICROPLANTS LAVANDULA ANGUSTIFOLIA MILL. AT LONG-TERM REPRODUCTION IN VITRO
Authors: Babanina Svetlana , Egorova Natalya , Yakimova Olga , Kovalenko Mariya
Published: October 2023

The purpose of the study is to identify the features of adaptation to ex vitro conditions of lavender plants after long-term clonal micropropagation. The experiments were carried out on microplants of narrow-leaved lavender (Lavandula angustifolia Mill.), cv. The number of plants in each subcultivation - n=10 pcs., 3-fold repetition. Microplants with well-developed shoots and roots were planted in a mixture of peat and perlite (1:1) and grown at illumination of 2–3 klx, photoperiod duration of 16 h, temperature of 24 ± 2°C, air humidity of 70%. The frequency of adaptation of microplants, depending on the number of subcultivations, varied slightly and amounted to 83...100%. On the 60th day of adaptation, the length of the shoot was significantly higher by 21...28% in microplants after 8 subcultivations (206.73 mm) compared with 14, 15 and 16 passages. There were no differences in the length of additional shoots depending on the amount of subculturing. According to the number of nodes on the main shoot, a tendency to their decrease with an increase in the number of passages was observed. A significant increase in the content of chlorophyll a with an increase in the number of subcultivations on the 14th day of adaptation was revealed, however, later these differences leveled out. On average, the in vitro viability index for passages was 1.45 and increased up to 30 days of adaptation to 1.75. The revealed features of changes in morphometric and physiological parameters indicate a good adaptive ability of the analyzed plants, while micropropagation in vitro during 16 subcultivations did not significantly reduce their adaptive potential. The optimal period of ex vitro adaptation is the period of 45...60 days, during which the plants formed well-developed shoots (3.20...6.00 g) and root system (0.619...1.143 g).
Use of probiotics in the treatment of selected psychiatric disorders
Authors: Skowrońska Magdalena Marianna
Published: October 2023

Aim
Probiotics are live microorganisms that are part of the human microbiota. The intestines are the habitat for approximately 1013-1014 microorganisms, mainly Firmicutes and Bacteroidetes. The gut microbiota is an individual characteristic for each person and can change due to many factors, including: age, diet, and health status. The gut microbiota plays a key role in the proper functioning of the brain-gut axis, thus contributing to human health and mental well-being. The aim of this study was to present the effect of probiotic use in the course of selected psychiatric disorders.
Material and methods
The literature review was performed using information from PubMed/Medline, ScienceDirect, and Polish Psychiatry databases that were published before 2022.
Results and discussion:
A factor associated with disorders such as depression, autism, Alzheimer's disease, and mental anorexia is the generalized inflammation taking place in the patient's body. Research indicates that the inflammatory response may be caused by an imbalance in the intestinal barrier and disruption of its continuity, which may result in translocation of bacteria into the blood and activation of the immune system. The use of probiotics may play a significant role in maintaining the bacterial balance in the gastrointestinal tract and the proper functioning of the gut-brain axis, which provides a link between gut function and the emotional and cognitive centers of the brain.
Conclusions
Probiotics may improve mental health and cognitive function, but more clinical studies are needed on the clinical significance of the effects and how they compare to current therapies.
The need for interdisciplinary quality of life studies for patients with Crohn's Disease - a systematic review
Authors: Saad Dominika Jean
Published: October 2023

Crohn’s disease is a chronic, lifelong condition with increasing rates of morbidity. It can have a significant impact on one's physical, emotional, economical and social functioning. Both medical as well as social fields of studies have adapted the construct of Quality of Life to assess the well being of patients. The purpose of this paper is to investigate the nature of scientists research concerning Quality of Life in Crohn's disease patients from an interdisciplinary, medical and psychological perspective exceeding beyond a single definition or a paradigm. EBSCOhost Research Databases platform was used to conduct the preliminary search. Then, a further qualitative analysis of texts was conducted. The results showed a declining interest in Quality of Life of Crohn’s disease patients in the studied 10-year scope on average by 11.49% from year to year. Also an underrepresentation of studies of the nature of psychological variables in relation to studies of the medical description was found. An information gap in scientific cognition related to the interdisciplinary approach regarding the studied topic was recognised. There is a necessity to broaden the horizons of the conducted research to include further issues at several levels of inference. This approach would by all means be needed not only in the dimension of scientific considerations, but also or above all in the practical dimension.
Between “Yesterday and Today”. A description of group therapy in the Department of Child and Adolescent Psychiatry, Jagiellonian University Medical College, Krakow.
Authors: Kudła Klaudiusz Krzysztof , Bogusz-Corkill Anna , Szwajca Marta , Szczudrawa Angelika , Cygankiewicz Patrycja , Śmierciak Natalia , Furman Katarzyna , Widelska Kinga , Matusiak Feliks , Pilecki Maciej
Published: October 2023

The following article is an attempt to present the model of group interaction conducted in the Department of Child and Adolescent Psychiatry of the University Hospital in Krakow. It describes both the beginnings of group interaction conducted by the team of Prof. M. Orwid, Prof. J. Bomba and dr W. Badure- Madej as well as the model developed by the current team of the clinic. The structure and setting of group interaction conducted in the stationary ward, the therapeutic framework, supervision process, and the method of conducting group therapy are described. The article describes the changes in the understanding and conduct of group therapy that have taken place over the years.
Clinical and metabolic associations of obesity and body mass index in antipsychotic-naïve first-episode schizophrenia patients and nonadherent chronic patients
Authors: Nadalin Sergej , Peitl Vjekoslav , Karlović Dalibor , Sučić Petra , Zatković Lena , Buretić-Tomljanović Alena
Published: October 2023

Aim of the study

We investigated the association between obesity and body mass index (BMI) with Positive and Negative Syndrome Scale (PANSS) psychopathology, age at disease onset, and parameters linked to the metabolic syndrome (fasting plasma lipid and glucose levels), among antipsychotic-naïve first-episode schizophrenia (AN-FES) patients and nonadherent chronic schizophrenia individuals.

Subject or material and methods

We recruited a total of 187 AN-FES patients or nonadherent chronic individuals for this study. Clinical and anthropometric data together with plasma lipid and glucose parameters were collected immediately after patients’ admission to the hospital. Patients were classified as obese with body mass index (BMI) ≥ 30, or as non-obese if overweight (BMI: 25 – 29.9) or of normal body weight (BMI: 18.5 – 24.9).

Results

After controlling for the possible confounders we found that only BMI significantly predicted clinical and metabolic variables. Among AN-FES patients, higher BMI values predicted lower levels of HDL cholesterol (HDL-c), and higher ratios for LDL cholesterol (LDL-c)/HDL-c and triglyceride/HDL-c, while among nonadherent individuals, higher BMI values predicted higher number of psychotic episodes, and lower PANSS general psychopathology scores. The contribution of BMI ranged from approximately 5.8% to 29.6%, with the lowest contribution observed for number of psychotic episodes, and the highest contribution for the LDL-c/HDL-c ratio.

Discussion

Our results indicate that AN-FES patients and nonadherent chronic patients differed in the effects of BMI.

Conclusions

Higher BMI contributes to an increased risk for dyslipidemia among AN-FES patients and to the higher number of psychotic episodes, and less severe clinical psychopathology among nonadherent chronic schizophrenia individuals.
From editors
Authors: Cyranka Katarzyna , Samochowiec Jerzy
Published: October 2023

Dear Readers Between Yestarday and Today ...With this words we open the autumn issue of Archives of Psychiatry and Psychotherapy. This is also the opening phrase of the first paper prepared by the Krakow team of Klaudiusz Kudła et al, prepared under the supervision of Maciej Pilecki. The article describes the transition of the model of group interaction conducted in the Department of Child and Adolescent Psychiatry of the University Hospital in Krakow, Poland - from its beginnings conducted by Prof. M. Orwid, Prof. J. Bomba and dr W. Badure-Madej throughout the changes that have taken place over the years.
Makamların dönüşümünün tarihsel ve kuramsal izleri: Zirefkend’in Kûçek’e dönüşümü
Authors: Berkman Esra , Taşdelen Duygu
Published: October 2023

Bu çalışmada incelenen iki makamdan biri olan Zirefkend, az kullanılan / nadir makam kategorisinde olup, elimizdeki eser örneği altıdır. Diğer taraftan yüzyıllar içinde Zirefkend’in dönüştüğünü varsaydığımız Kûçek makamı dağarda 16 eser ile temsil edilmektedir. Repertuvarda karşılaşılan söz konusu durum, bu çalışmanın başlıca bir motivasyonunu oluşturmaktadır. Kültürel belleğimizin önemli bir kısmını oluşturan Türk makam müziğinin yozlaşmaması ve bu geleneğin yeni kuşaklara özgün biçimde aktarılabilmesi için, hem geçmişten günümüze makamların kuramsal bağlamda netlikle ortaya konmaları hem elde edilen kuramsal bilgilerle eserlerin makam analizinin düzgün yapılması önem arz etmektedir. Bu bağlamda, günümüzde kullanılan Pithagoryen makamsal kuramın en erken dayanaklarından biri olan Urmevî’nin Kitâbü’l Edvâr’ı ile Şerefiyye Risâlesi’nden seçilen ve günümüze az eser örneği ulaşan Zirefkend makamının nasıl olup da Kûçek makamına dönüşmüş olabileceği araştırılmıştır. Nitekim seçilen iki makamdaki eserlerin makam analizleri yapılıp, bu analizlere dayanarak, yaşanmış olması muhtemel dönüşüm ortaya konmaya çalışılmıştır. Bu çerçevede, Safiyyüddin’den günümüze makam kuramının anlatılmaya çalışıldığı yazmalar üzerinde yapılan incelemeler zemininde, bahsi geçen makamlar irdelenmiştir ve bunlar kuram bilgilerimizin temelini oluşturmuştur. Nitel yönteme dayalı olarak yaptığımız makamsal analiz, Anadolu edvar ekolü itibariyle kullanılagelen ve bestesel seyre dayalı olan yaklaşımdan, Safiyyüddin’den aldıkları bilgileri Batı porteli tonal düzleme uyarlayan Yekta’nın ve Arel-Ezgi-Uzdilek’in (AEU) ortaya koydukları yaygın yaklaşıma dek, pek çok modele atıfla desteklenmiştir. Sonuç olarak, edvar kitaplarının en erken nüshaları ile daha sonraki istinsahları arasında bir karşılaştırma dahi adı geçen makamın adının Zirefkend’den, Zirefkend-i Kûçek ya da Kûçek’e evrildiğini birkaç örnekte tespit etmemizi sağlamaktadır. Yine de makam analizi çerçevesinde birkaç çıkarsama yapılabilmekle birlikte, eser sayısının azlığı bilimsel bir sonuca varmayı engelleyecek niceliktedir. 20. Yüzyıl makam müziği bestecilerinin ise söz konusu makamlardaki eserlerini, AEU sistemince ele alınan makam tarifleri uyarınca besteledikleri netlikle görülmüştür.
Cami görevlileri için geliştirilen ses eğitimi konulu hizmet içi eğitim programının etkililiğinin incelenmesi
Authors: Kaya Levent , Özden Erhan , Alcı Bülent
Published: October 2023

Cami görevlileri (imam, müezzin) dini ritüeller esnasında Kur’an-ı Kerim, ezan, salâ, mevlid gibi dini müzik formlarını icra ederler. Bunların yanı sıra hutbe okumak ve vâzetmek gibi görevlerini ifa ederken ses becerilerini kullanırlar. Cami görevlilerinin mesleki ihtiyaçlarının belirlenmesine yönelik farklı örneklemlerle yapılmış çalışmalarda yer alan katılımcılar, alanında uzman kişiler tarafından doğru içerik ve kaynaklarla iyi programlanmış bir ses eğitimi programına ihtiyaç duyduklarını belirtmişlerdir. Cami görevlileri mesleklerini icra ederken ihtiyaç duydukları ses eğitimini, mezun oldukları okullardan (imam-hatip liseleri veya ilahiyat fakülteleri) karşılayamamaktadırlar. Bu araştırmanın amacı cami görevlileri için geliştirilen ses eğitimi konulu hizmet içi eğitim programının etkililiğini belirlemektir. Araştırmanın deneysel işlemi, Diyanet İşleri Başkanlığı İstanbul Haseki Reisulkurra Abdurrahman Gürses Dini İhtisas Merkezi’nde verilen Dini Musiki Hizmet İçi Eğitim Programı bünyesinde yürütülmüştür. Bu program kapsamında, İstanbul’un farklı ilçelerinde görev yapan imam-hatip, müezzin kayyımlar arasından sekiz katılımcı belirlenmiştir. İlgili literatür taraması ve çalışma grubuyla yapılan görüşmeler sonucu cami görevlilerinin ses eğitimi ihtiyaçları tespit edilerek 26 haftalık hizmet içi eğitim programı tasarlanmıştır. Uygulama 2020-2021 eğitim öğretim yılında yapılmıştır. Araştırmada, öntest-sontest tek gruplu deneysel desen kullanılmıştır. Veri toplama aracı olarak Cami Görevlileri için Ses Performansı Değerlendirme Ölçeği geliştirilmiştir. Bu ölçek 5’li Likert tipte bir ölçektir. Verilerin analizinde, ön test ve son test grup ortalamaları Wilcoxson işaretli sıralar testi kullanılmıştır. Araştırma sürecinde, çalışma grubunun ön test ve son test performanslarını değerlendirmek üzere üç akademisyenden oluşan bir uzman ekip görev almıştır. Veri toplama sürecinde ön test ve son test performans değerlendirmeleri için katılımcılardan görüntülü ses kayıtları da alınmıştır. Araştırma sonucunda, deney grubunun ön test ve son test puanları arasında anlamlı bir fark olduğu belirlenmiştir (Z=2,521, p˂0.05). Bu durumda geliştirilen ses eğitimi konulu hizmet içi eğitim programının cami görevlilerinin ses kullanma becerilerini geliştirdiği söylenebilir. İlerideki araştırmalarda, geliştirilen bu ses eğitimi konulu hizmet içi eğitim programının etkililiğinin deney kontrol gruplu deneysel desenle test edilmesi sağlanabilir.
Fusion after a failed primary total ankle arthroplasty
Authors: Jennison Toby , Ukoumunne Obioha C. , Lamb Sallie , Sharpe Ian , Goldberg Andrew J.
Published: October 2023

Aims

When a total ankle arthroplasty (TAA) fails, it can be converted to a fusion or a revision arthroplasty. Despite the increasing numbers of TAAs being undertaken, there is little information in the literature about the management of patients undergoing fusion following a failed TAA. The primary aim of this study was to analyze the survival of fusions following a failed TAA using a large dataset from the National Joint Registry (NJR).

Methods

A data linkage study combined NJR and NHS Digital data. Failure of a TAA was defined as a fusion, revision to a further TAA, or amputation. Life tables and Kaplan-Meier graphs were used to record survival. Cox proportional hazards regression models were fitted to compare the rates of failure.

Results

A total of 131 patients underwent fusion as a salvage procedure following TAA. Their mean age was 65.7 years (SD 10.6) and 73 (55.7%) were male. The mean follow-up was 47.5 months (SD 27.2). The mean time between TAA and fusion was 5.3 years (SD 2.7). Overall, 32 (24.4%) underwent reoperations other than revision and 29 (22.1%) failed. Of these 24 (18.3%) underwent revision of the fusion and five (3.8%) had a below-knee amputation. No patients underwent conversion to a further TAA. Failure usually occurred in the first three postoperative years with one-year survival of fusion being 96.0% (95% confidence interval (CI) 90.7 to 98.3) and three-year survival in 69 patients being 77.5% (95% CI 68.3 to 84.4).

Conclusion

Salvage fusion after a failed TAA shows moderate rates of failure and reoperations. Nearly 25% of patients required revision within three years. This study is an extension of studies using the same methodology reporting the failure rates and risk factors for failure, which have recently been published, and also one reporting the outcome of revision TAA for a failed primary TAA, using the same methodology, which will shortly be published.

Cite this article: Bone Joint J 2023;105-B(10):1094–1098.
Paediatric hip ultrasound
Authors: Donnan Matthew , Anderson Nathan , Hoq Monsurul , Donnan Leo
Published: October 2023

Aims

The aim of this study was to investigate the agreement in interpretation of the quality of the paediatric hip ultrasound examination, the reliability of geometric and morphological assessment, and the relationship between these measurements.

Methods

Four investigators evaluated 60 hip ultrasounds and assessed their quality based the standard plane of Graf et al. They measured geometric parameters, described the morphology of the hip, and assigned the Graf grade of dysplasia. They analyzed one self-selected image and one randomly selected image from the ultrasound series, and repeated the process four weeks later. The intra- and interobserver agreement, and correlations between various parameters were analyzed.

Results

In the assessment of quality, there a was moderate to substantial intraobserver agreement for each element investigated, but interobserver agreement was poor. Morphological features showed weak to moderate agreement across all parameters but improved to significant when responses were reduced. The geometric measurements showed nearly perfect agreement, and the relationship between them and the morphological features showed a dose response across all parameters with moderate to substantial correlations. There were strong correlations between geometric measurements. The Graf classification showed a fair to moderate interobserver agreement, and moderate to substantial intraobserver agreement.

Conclusion

This investigation into the reliability of the interpretation of hip ultrasound scans identified the difficulties in defining what is a high-quality ultrasound. We confirmed that geometric measurements are reliably interpreted and may be useful as a further measurement of quality. Morphological features are generally poorly interpreted, but a simpler binary classification considerably improves agreement. As there is a clear dose response relationship between geometric and morphological measurements, the importance of morphology in the diagnosis of hip dysplasia should be questioned.

Cite this article: Bone Joint J 2023;105-B(10):1123–1130.
Comparison of two hydroxyapatite-coated femoral components: a randomized clinical trial using radiostereometric analysis
Authors: Turgeon Thomas R. , Righolt Christiaan H. , Burnell Colin D. , Gascoyne Trevor C. , Hedden David R. , Bohm Eric R.
Published: October 2023

Aims

The primary aim of this trial was to compare the subsidence of two similar hydroxyapatite-coated titanium femoral components from different manufacturers. Secondary aims were to compare rotational migration (anteversion/retroversion and varus/valgus tilt) and patient-reported outcome measures between both femoral components.

Methods

Patients were randomized to receive one of the two femoral components (Avenir or Corail) during their primary total hip arthroplasty between August 2018 and September 2020. Radiostereometric analysis examinations at six, 12, and 24 months were used to assess the migration of each implanted femoral component compared to a baseline assessment. Patient-reported outcome measures were also recorded for these same timepoints. Overall, 50 patients were enrolled (62% male (n = 31), with a mean age of 65.7 years (SD 7.3), and mean BMI of 30.2 kg/m2 (SD 5.2)).

Results

The two-year subsidence was similar for Avenir (-0.018 mm (95% confidence interval (CI) -0.053 to 0.018) and Corail (0.000 mm (95% CI -0.027 to 0.026; p = 0.428). Both anteversion/retroversion (Avenir 0.139° (95% CI -0.204 to 0.481°); Corail -0.196° (95% CI -0.445 to 0.053°; p = 0.110) and varus/valgus tilt (Avenir -0.024° (95% CI -0.077 to 0.028); Corail -0.049° (95% CI -0.098 to 0.000°; p = 0.473) were not statistically significantly different. After two years, patients reported similar improvements in EuroQol five-dimension five-level health questionnaire (Avenir 0.22 (SD 0.2); Corail 0.22 (SD 0.18); p = 0.965) and other outcomes scores. Patient satisfaction on a five-point Likert scale was also similar between both groups after two years (Avenir 1.38 (SD 0.88); Corail 1.33 (SD 0.57); p = 0.846).

Conclusion

The performance of both femoral components was similar in terms of stability and patient outcomes.

Cite this article: Bone Joint J 2023;105-B(10):1045–1051.
Cochrane Corner
Authors: Marson Ben A.
Published: October 2023

This edition of Cochrane Corner looks at some of the work published by the Cochrane Collaboration, covering pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic, and long bone fractures; interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews; and pharmacological treatments for low back pain in adults: an overview of Cochrane Reviews
Short Communication: The isolation of Klebsiella variicola’s cellulase from Macrotermes gilvus gut in Indralaya Peatlands, Indonesia
Authors: OKTIARNI DWITA , HERMANSYAH HERMANSYAH , IBRAHIM EDDY , MARSI MARSI , HASANUDIN HASANUDIN , MIKSUSANTI MIKSUSANTI , YANTO DEDE HERI YULI , RAHMANI NANIK , KASMIARTI GETARI
Published: October 2023

Abstract. Oktiarni D, Hermansyah, Ibrahim E, Marsi, Hasanudin, Miksusanti, Yanto DHY, Rahmani N, Kasmiarti G. 2023. Short Communication: The isolation of Klebsiella variicola’s cellulase from Macrotermes gilvus gut in Indralaya Peatlands, Indonesia. Biodiversitas 24: 4218-4222. Termites are organisms that can inflict damage on agricultural, forest, and furniture materials. Furthermore, they can positively affect the ecosystem due to their ability to break down lignocellulose-containing materials. According to previous findings, the cellulolytic bacteria from the termite Macrotermes gilvus gut obtained in Indralaya Peatlands showed activity and hydrolyzed cellulose in a CMC agar medium. In this study, the cellulase enzymes of Klebsiella variicola isolated from Macrotermes gilvus gut showed higher cellulolytic indexes after staining with Congo red. Furthermore, the enzyme was purified and characterized using ammonium sulfate precipitation and dialysis. SDS PAGE and zymogram analysis reported a molecular mass of 20 kDa, with optimal activity at pH of 6 and temperature of 50°C.
Reproductive performances of triploid male and female Nile tilapia Oreochromis niloticus (Linnaeus, 1758) at different ages
Authors: CARMAN ODANG , MUKTI AKHMAD TAUFIQ , ZAIRIN JR. MUHAMMAD , ALIMUDDIN ALIMUDDIN
Published: October 2023

Abstract. Carman O, Mukti AT, Zairin JR M, Alimuddin. 2023. Reproductive performances of triploid male and female Nile tilapia Oreochromis niloticus (Linnaeus, 1758) at different ages. Biodiversitas 24: 4235-4242. Triploidization has been known as a chromosome set manipulation strategy to produce sterile fish. This study aimed to examine the reproductive and sterility performances of triploid male and female Nile tilapia Oreochromis niloticus (Linnaeus, 1758) at different ages. The triploidization process using heat shock of 41°C for four minutes at four Minutes After Fertilization (MAF) of the zygote old made the population of triploid tilapia. Two steps of fish rearing were conducted, namely indoor fish rearing and outdoor fish grow-out. Fish were reared in a controlled laboratory (indoor) at the Reproduction and Genetics Laboratory of Aquatic Organisms, Department of Aquaculture, Faculty of Fisheries and Marine Science, IPB University for four months, and then fish grow-out was performed in a controlled pond for two months. Reproductive performances such as Hepatosomatic Index (HSI), Gonadosomatic Index (GSI), gonadal development, and sterility of triploid and diploid for both male and female tilapias were analyzed. These results showed that triploid tilapia generally indicated late gonadal development and growth compared to diploids before and during maturation. Triploid female tilapia showed a lower HSI than diploid female tilapia (P<0.05). Otherwise, triploid and diploid males showed the same HSI. GSI of triploid males and females were lower than diploid males and females (P<0.05) at every age, namely three-, four-, five- and six-month-old fish. Based on the size and histology of the gonad, triploid male and female tilapias showed sterile characteristics with gametogenesis inhibition.
Phytochemical diversity and biological activities of Curcuma species from the East Coast of Peninsular Malaysia
Authors: YURASBE NUR QISTINA , DIN NURUL ATHIFAH , PALANIVELOO KISHNETH , MANIKAM SASHIKALA , NAGAPPAN THILAHGAVANI
Published: October 2023

Abstract. Yurasbe NQ, Din NA, Palaniveloo K, Manikam S, Nagappan T. 2023. Phytochemical diversity and biological activities of Curcuma species from the East Coast of Peninsular Malaysia. Biodiversitas 24: 4243-4252. Zingiberaceae has been associated with traditional medicine for centuries. The genus Curcuma is traditionally famous and economically important for its therapeutic and nutritional values. Over 50 genera of 1600 species are recorded worldwide, with the highest concentration in the Malesian region, including Indonesia, Borneo, Thailand, Malaysia, Vietnam, Cambodia, Myanmar, and the Philippines. We investigated the methanolic crude extracts of Curcuma aeruginosa, Curcuma caesia, Curcuma longa, Curcuma xanthorrhiza, and Curcuma zedoaria from Terengganu for their phytochemicals, total phenolic content (TPC) using Folin-Ciocalteu colorimetric method, total flavonoid content (TFC) using aluminum chloride colorimetric method, antioxidant activity using the 2,2-diphenyl-1-picryl-hydrezyl (DPPH) radical scavenging activity and toxicity using brine shrimp lethality test (BSLT). Phytochemical screening revealed alkaloids, flavonoids, phenolics, saponins, tannins, triterpenoids, glycosides, lignins, and oils in all species investigated. Curcuma longa extract had the highest phenolic and flavonoid content with the value of 155.31±1.78 mg GAE/g and 151±8.35 mg quercetin/g, respectively as well as best antioxidative potential with IC50 value of 88.65±0.6 mg/mL, followed by C. zedoaria (98.61±5.23 mg/mL), C. aeruginosa (142.51±3.29 mg/mL), C. xanthorrhiza (150.01±0.63 mg/mL) and C. caesia (156.4±0.67 mg/mL). Curcuma caesia displays the lowest degree of toxicity compared to the other species, with the LC50 value of 11585 mg/mL) considered non-cytotoxic. Hence, the selected Curcuma species has potential therapeutic value to be developed into pharmaceutical due to its significant bioactive potentials and potent antioxidant capacity.
Stratified haploid identification system through the R1-nj kernel and reduced seedling vigor in tropical maize germplasm
Authors: THAWARORIT ARNAT , DERMAIL ABIL , LERTRAT KAMOL , CHANKAEW SOMPONG , SURIHARN KHUNDEJ
Published: October 2023

Abstract. Thawarorit A, Dermail A, Lertrat K, Chankaew S, Suriharn K. 2023. Stratified haploid identification system through the R1-nj kernel and reduced seedling vigor in tropical maize germplasm. Biodiversitas 24: 4262-4268. Haploid identification through the R1-nj marker is commonly applied in in-vivo doubled haploid technology in maize, although misclassification issues often occur. We explored the innate properties of maternal haploids at the seedling stage to verify true haploids and to reduce false positives. There are many questions about whether reduced seedling vigor is effective for haploid verification in tropical maize backgrounds. This study aimed to evaluate the haploid induction rate of Stock6-derived F3 population inducers and to investigate the effectiveness of reduced seedling vigor at the V2/V3stage as an alternative marker to verify putative haploids. Field trials and haploid induction were conducted in the rainy season of 2021 and the dry season of 2021/22 in Khon Kaen, Thailand. Two tropical source germplasm: P789 and S7328, were included as donor females. Haploids were identified through the R1-nj marker and reduced seedling vigor. Significant reduction of haploid frequency up to 2.5% on average between the two identification methods, indicating that a considerable number of false positives could be found using reduced seedling vigor. Inducer population K11 was promising since it performed a stable ability to produce haploids over donors and seasons and had a low misclassification rate. Further breeding strategies and haploid selection schemes are discussed.
Isolation and molecular characterization of probiotic from Sidamanik green tea (Camellia sinensis) fermentation
Authors: FAHMI ALIYAH , SYUKUR SUMARYATI , CHAIDIR ZULKARNAIN , MELIA SRI
Published: October 2023

Abstract. Fahmi A, Syukur S, Chaidir Z, Melia S. 2023. Isolation and molecular characterization of probiotic from Sidamanik green tea (Camellia sinensis) fermentation. Biodiversitas 24: 4277-4288. The bioavailability of green tea catechins is reduced in the gastrointestinal tract because of its instability. Probiotics are expected to increase their bioavailability in the gastrointestinal tract.There is no any information about Sidamanik fermented green tea, either probiotics, antimicrobial activity, or probiotic species that are beneficial to health. This research aims to isolate and test the characterization of probiotics from fermented green tea. Green tea from Sidamanik Sub-district was fermented with palm sugar and forest honey with 24, 48, and 72 h variation times. The fermented green tea was tested for morphological characterization,Gram staining, catalase test, and fermentation test. Then the resistance test to bile acids and salts and the antimicrobial activitytest against three pathogenic bacteria Escherichia coli Q157:H7, Staphylococcus aureus ATCC25923, and Listeria monocytogenes CFSAN004330. Two strains were selected from this series of tests, which were identified using 16S rRNA gene sequencing from different green tea fermented at the same fermentation time. The results indicated a positive lactic acid bacteria (LAB) morphological test. The characteristics of LAB can be described as a single colony being seen with a round, smooth, yellowish-white color, and a clear zone was formed around the colony, positive Gram, negative catalase, and homofermentative. LAB strains 1.1., and 4.1 were chosen to test their antimicrobial activity because they had the best acid and salt resistance viability. Then the results of molecular identification of 16S rRNA gene found that the probiotics contained in LAB strain 1.1. was Lactobacillus plantarum Y-1 and in LAB strain 4.1 was Lacticaseibacillus paracasei HBUAS62903. This study aims to find a new product of fermented green tea that has benefits in digestive health because it contains naturally processed lactic acid bacteria, is cheaper, simpler, stable at room temperature, durable in storage, and easy to serve.
Chemical characterization of mint (Mentha spp.) germplasm from Central Java, Indonesia
Authors: LIANAH LIANAH , KUSUMARINI NIKEN , HAFSHAH MUTISTA , KRISANTINI KRISANTINI , KURNIAWATI ANI , AHMAD MILYA URFA
Published: October 2023

Abstract. Lianah L, Kusumarini N, Hafshah M, Krisantini K, Kurniawati A, Ahmad MA. 2023. Chemical characterization of mint (Mentha spp.) germplasm from Central Java, Indonesia. Biodiversitas 24: 4307-4313. The main objective of this work was to evaluate and compare the leaf production and oil content of the four mint genotypes (Mentha spp.) from Central Java, Indonesia. Four genotypes were collected from Rejosari Village, Kudus District, Central Java, Indonesia, namely spearmint (Mentha spicata), peppermint (Mentha x piperita), orange mint (Mentha x piperita ‘Orange’) and chocolate mint (Mentha x piperita ‘Chocolate’). Essential oil extraction was carried out by steam distillation. Identification of the chemical compounds of the oil and their relative percentage were analyzed using GC-MS. Leaves productivity ranged between 500-1000 kg/ha, and essential oil content from 0.4 to 1.36%. The major essential oil constituents detected were 1,8-cineole, carvone, limonene, linalool, linalyl acetate, menthol, menthone, menthyl acetate, and piperitenone oxide. Chocolate mint had the highest leaf production and the highest content of essential oil (4.17%) and menthone yield (28%) compared to the other genotypes.
Tree species diversity adapted to Pinus merkusii forests in Gunung Ciremai National Park, West Java, Indonesia
Authors: SUPARTONO TOTO , ADHYA ILHAM , KOSASIH DEDE , WILDANI WILLY
Published: October 2023

Abstract. Supartono T, Adhya I, Kosasih D, Wildani W. 2023. Tree species diversity adapted to Pinus merkusii forests in Gunung Ciremai National Park, West Java, Indonesia. Biodiversitas 24: 4314-4323. One of the challenges faced in rehabilitating pine forests in conservation areas is the limited information on plant species capable of adapting to these ecosystems. This study aimed to analyze the diversity of tree species that grow and adapt to pine forests and the relationship of natural forests with the vegetation characteristics of pine forests. The research was conducted in pine forests bordering natural forests and far from natural forests using the sample plot method. The study recorded 44 species from 27 families of seedlings, 46 species from 21 families of saplings, 25 species from 18 families of poles, and 24 species from 17 families of trees. Accumulation of species from all growth stages recorded 83 species (76 local species and 7 cultivated species) from 39 families. Based on the species accumulation curve, pine forests adjacent to natural forests have more species than those far from natural forests. Individual and family density in pine forests adjacent to natural forests were also higher than the density of these two variables in pine forests far from natural forests. Furthermore, both the pine forest adjacent to the natural forest and that far from the natural forest, each has its own species peculiarities. The results indicate that the existence of natural forests has an important role as a source of biodiversity for the surrounding ecosystem. As an implication of this study, species that can grow to the level of poles and trees can be recommended as rehabilitation plants in the Pinus merkusii Jungh. & de Vriese forests in Gunung Ciremai National Park, Indonesia because pine is not a local species and the allelopathy it releases can reduce plant diversity.