bluuebunny/crossref_metadata_2025 huggingface dataset:
Quality assessment of nutrition information published weekly in the surrounding of four hospitals in Lima, Peru
Authors:   Universidad Norbert Wiener, Del Carpio Carhuas T , Torres Najar M , Dextre M ,   Universidad Mayor de San Marcos, Rodríguez Huamán Y , Rivera-Lozada O , Lozada-Urbano M
Published: October 2022

There is a growing demand from the general public regarding nutrition topics that has prompted social media such as magazines, newspapers, television, radio and the internet to include more nutritional content. The purpose of this study was to assess the quality of nutrition information published by health weeklies in the surroundings of four hospitals in Lima, Peru. A cross- sectional study was conducted using a mixed methodological design involving both quantitative and qualitative analyses. Thirty-seven hard copies of 4 health weeklies were purchased over the 10- week study period. Bivariate Logistic Regression was performed to examine all available journal characteristics associated with the quality of provided information. Logistic Regression Models were estimated for the independent variables that showed statistical significance in the bivariate analysis. Weekly publications with the highest percentage of pages dedicated to nutrition were “My Health” (41.67%), “Natural Health” (48.6%) and those with the lowest percentage were “Sun, medicine and beauty” (19.37%) and “Health, Money and Love” (18.34%). Collected publications included 185 articles that were classified into two groups regarding the validity of the nutrition information presented: supported 50.3% (93/185) and unsupported 49.7% (92/185). Statistical analysis for quality estimated that the “name of weekly” had a p value=0.000, the “topic” had a p value=0.035, and the “objective, source description, quarter of publications” had a p value >0.05. Multivariate logistic regression reports that only the variable “name of the weekly” had statistical significance with p values less than 0.05. The percentage of nutrition information suggests that editors may not be applying journalistic principles and shows the importance of interdisciplinary work, between nutritionists and health journalists, to improve health status of the general population. In the case of weekly health publications, editors responsible for this type of written press could benefit from including nutritionists in charge of providing nutritional information. Key words: health, journalists, nutrition, nutritional content, quality of information, weeklies
Uniwersalizm vs. tradycjonalizm – różne racjonalności, odmienne antropologie
Authors: Kopeć-Kaczor Anna
Published: October 2022

Artykuł przedstawia tezę (postawioną przez Alasdaira MacIntyre'a), że spór o znaczenie takich pojęć jak ‘tożsamość’, ‘podmiotowość’, ‘wolność’, jest nierozstrzygalny. Konflikty wokół nich opierają się na błędnym założeniu, że istnieje tylko jedna prawdziwa racjonalność. MacIntyre konfrontuje taką koncepcję (uniwersalizm) z podejściem, które przyznaje, że istnieje wiele różnych rodzajów racjonalności (zakorzenionych w różnych tradycjach). Pierwsza część artykułu prezentuje jak MacIntyre rozumie uniwersalność i tradycję Druga koncentruje się na takich pojęciach, jak tożsamość i wolność, rozwijanych przez dwie tradycje: liberalizm i etykę cnoty. Na koniec przedstawia wniosek, że czynnikiem odróżniającym od siebie te dwie tradycje jest fakt istnienia (nieistnienia) dóbr doskonałości.
AHOL AZ ÉG ÉS FÖLD ÖSSZEÉR
Authors: UTASI Anikó
Published: October 2022

A dolgozat Domonkos István 1970-ben megjelent Via Italia című ifjúsági regényével foglalkozik. Az író opusában jelentős helyet elfoglaló műről kevés elemzés született ez idáig. Tulajdonképpen ez az állítás igaz Domonkos egész gyermekirodalmi munkásságára is. A tanulmány szerzője arra keresi a választ, mitől annyira friss ez a regény több mint ötven évvel az első kiadása után is. Az elemzés számba veszi a regény jellemző helyszíneit (nyelvi és fizikai tereit), rétegeit és szereplőit egyaránt. Továbbá azt a domonkosi életérzést kísérli megragadni, mely majd a gyermekversek sajátja is lesz (Tessék engem megdicsérni), s amely korosztályok feletti, valódi crossover művekké avatja mind az említett verseket, mind a regényt.
KÁNON, MINORITÁS, IRODALOM
Authors: MEDVE Zoltán
Published: October 2022

A minoritás fogalmát, akárcsak a kánonét, „multifokális” és relativizálható voltából adódóan lehetetlen egyértelműen meghatározni. Rendelkezünk különféle kulcsszavakkal és ezek definícióival: az irodalmi kánon esetében mindenekelőtt a világirodalmi, a nemzeti és a privát kánonról, a minoritással kapcsolatban például a Közép-Európában kialakult földrajzi, geopolitikai, illetve etnikai, vallási és nyelvi minoritásról. Konszenzus ugyanakkor egyik fogalommal kapcsolatban sincsen, a határok mindkét esetben legtöbbször összemosódnak és átfedik egymást. A dolgozat középpontjában a kánon és a kisebbségi irodalom, illetve a fenti két fogalom lehetséges korrespondenciái állnak: a minoritás kortárs exjugoszláviai és magyar nyelvű irodalma, valamint a kanonizáció kapcsolatának vizsgálatára tesz kísérletet.
MINORITÁSOK TOMPA ANDREA FEJTŐL S LÁBTÓL: KETTŐ ORVOS ERDÉLYBEN CÍMŰ REGÉNYÉBEN
Authors: BALOGH Magdolna
Published: October 2022

Tompa Andrea regénye a kisebbségi léthelyzetek egzisztenciális, társadalmi és kulturális dimenzióinak sokaságát és a minoritásra/minoritásokra mint adottságra, mint (többnyire korlátozó) létlehetőségre adott válaszok, magatartások széles skáláját mutatja be individuálpszichológiai és társadalom-lélektani aspektusban egyaránt. Az alábbi értelmezésben a műben megjelenített kisebbségi léthelyzetek közül kettőt emelek ki: 1. az első világháború és Trianon következtében kisebbségbe kényszerülő magyarság helyzetének új szempontú megközelítését, amelynek révén a mű érvényes ellennarratívát tud megfogalmazni a hivatalos magyar emlékezetpolitika történelemhamisító Trianon-retorikájával szemben. 2. A női főhős alakján keresztül az emancipáció problémáinak a feminizmussal és a genderszempontokkal érintkező bemutatását, amelyek ábrázolása során egyetemes érvényű problémákra mutat rá.
A KEVEREDÉS VIHAROS VÖLGYE
Authors: MIKOLA Gyöngyi
Published: October 2022

А tatár származású Guzel Jahina ma egyike a legnépszerűbb kortárs orosz íróknak. A Zulejka kinyitja a szemét és A Volga gyermekei című regényeit, melyek magyarul is olvashatóak, számos rangos hazai és nemzetközi díjjal tüntették ki, utóbbi többek között 2019-ben Szerbiában elnyerte az Ivo Andrić-díjat. Mindkét műben egy-egy etnikai kisebbség képviselőjének története bontakozik ki a 20-as, 30-as évek szovjet korszakának történelmi kontextusában. Zulejka krími tatár asszony, akit a kuláktalanítás során deportálnak Szibériába, Jacob Ivanovics Bach tanító pedig a Volga menti német telepesek leszármazottja, akinek az életét fenekestül felforgatja az 1917-es bolsevik hatalomátvétel. Tanulmányomban arra keresem a választ, hogy milyen irodalmi kódok révén konstruálja meg szereplői sajátos, folyamatos átalakulásban lévő, „hibrid” identitásait Jahina prózája.
TRANSZKULTURÁLIS TAPASZTALAT ÉS TRANSZLINGVÁLIS FORMAALKOTÁS OTO HORVAT REGÉNYEIBEN
Authors: TOLDI Éva
Published: October 2022

A dolgozat Oto Horvat regényeiben a kulturális transzfer és a transzlingvalitás jelenségeit mutatja be. A szerző Újvidéken született, élt Magyarországon és Németországban, majd Olaszországban telepedett le. Önéletrajzi elemekkel átszőtt regényei ennek a helykeresésnek az eredőire és mikéntjére világítanak rá. Az én-identitás kérdései foglalkoztatják, amelyek szoros kapcsolatban állnak a többes kötődés tapasztalatával, valamint a határok átjárhatóságának kérdésével is. Azonban a referenciális vonatkozásoknál is jelentősebb, hogy munkái erőteljes kulturális beágyazottságúak. Ennek következtében többféle paradigmába is beleíródnak. Legújabb regénye, a Noćna projekcija [Éjszakai vetítés] beletartozik a fejlődésregények vagy a nagy korpusszal rendelkező Újvidék-regények sorába, ugyanakkor besorolható a más nyelven íródó magyar irodalom alkotásainak körébe is.
VÁROSI DIALEKTOLÓGIA MAGYARORSZÁGON
Authors: KONTRA Miklós
Published: October 2022

A városi dialektológia William Labov munkásságával kezdődött az 1960-as évek közepén az Egyesült Államokban. Magyarországon az MTA Nyelvtudományi Intézetében 1985-ben kezdődtek meg az élőnyelvi (szociolingvisztikai) kutatások. A Budapesti Szociolingvisztikai Interjú (röviden: BUSZI) az első jelentős magyar beszélt nyelvi kutatás volt, a terepmunkája 1987-ben (50 interjú), majd 1988‒89-ben (200 interjú) zajlott. A lejegyzés, kódolás, ellenőrzés, majd az adatbázis létrehozása és kutathatóvá tétele 2008-ig tartott. A dolgozat bemutatja a 2021-ben megjelent Tanulmányok a budapesti beszédről című könyvet, majd röviden szó lesz a BUSZI „kisöccséről”, a Szögedi Szociolingvisztikai Interjúról (SZÖSZI) is.
A SZÖVEGÉRTÉSI KÉPESSÉGEK ÖNREFLEXIÓS MEGÍTÉLÉSE ÉS A TÉNYLEGES TELJESÍTMÉNY KÖZÖTTI VISZONY VIZSGÁLATA
Authors: GERGELY Viktória , VANČO Ildikó
Published: October 2022

Jelen tanulmány célja a tanulók szövegértési képességeinek önreflexiós megítélése és a tényleges szövegértési teljesítménye közötti különbségek feltérképezése, valamint annak a kérdésnek a megválaszolása, hogy a tanulók milyen mértékben tudják értékelni saját szövegértési képességüket. A kutatásban 300 fő vett részt. A válaszadók szakértői mintavétel alapján, két korosztályból és hasonló kétnyelvű környezetből lettek kiválasztva. A vizsgált célcsoportok a kelet-, közép- és nyugat-szlovákiai kétnyelvű települések Magyar tannyelvű általános iskoláinak negyedikes és hetedikes diákjai voltak. A felmérés két részből állt. A vizsgálat egyik része önkitöltős kérdőíveket tartalmazott, amelyekben az olvasási szokásaikról és saját megítélés szerinti szövegértési képességeikről kérdeztük a diákokat. A válaszok az adatközlők szubjektív véleményén alapultak. A kérdőív kitöltése után a diákok kitöltötték a Nyitrai Konstantin Filozófus Egyetem Közép-európai Tanulmányok Kara Nyelvészeti Kutatócsoportja által összeállított szövegértési tesztet, ami a két korcsoport számára három-három, különböző típusú szöveget és az adott korcsoportok kognitív képességeihez alkalmazkodó kérdéseket tartalmazott. Az adatközlők válaszai segítségével felmérhetők voltak a különbségek a diákok önbevallásán alapuló becsült szövegértési képességei és az általunk készített szövegértési tesztek eredményei között. A két vizsgálat elemzése alapján megállapítható, hogy a résztvevők túlbecsülték szövegértési képességeiket, és saját szövegértésükről alkotott véleményük nem felel meg a szövegértési tesztek eredményeinek.
URGENSI PENDIDIKAN KARAKTER
Authors: Kosim Mohammad
Published: October 2022

AbstractCharacter education is a planned effort in helping someone to understand, care, and act based on ethical values / moral principles adopted. This paper seeks review of character education which is currently a major issue of national education. Several important issues are studied in this paper is about the meaning of character and character education, the reasons why education is important characters are developed, the foundation and source of character education, character values that need to be developed either in the form of universal values and the values unearthed a typical nation of religious values, Pancasila, the nation's cultural and national education goals. This paper also describes the implementation of character education strategy needs to be done in a systematic, holistic, and sustainable within the family, school and wider community. Kata-kata kuncikarakter, pendidikan karakter, tujuan pendidikan nasional
KEBIJAKAN PENDIDIKAN AGAMA ISLAM DI SEKOLAH PADA MASA ORDE LAMA
Authors: Kosim Mohammad Kosim
Published: October 2022

Artikel ini mendeskripsikan kebijakan pemerintah tentang mata pelajaran Pendi-dikan Agama Islam (PAI) di sekolah negeri selama masa Orde Lama (1945-1965).Yang menjadi pertanyaan adalah bagaimana kedudukan mata pelajaran PAI disekolah negeri selama pemerintahan Orde Lama? Melalui pendekatan historisdengan analisis dokumen terhadap sejumlah kebijakan terkait, diketahui bahwadi masa Orde Lama, pendidikan agama telah ditetapkan sebagai salah satu matapelajaran yang diajarkan di sekolah negeri, sesuatu yang hanya menjadi keinginanselama masa penjajahan. Namun, selama Orde Lama kedudukan matapelajaran PAI belum kokoh karena tidak menjadi mata pelajaran wajib, bahkanorang tua siswa dan murid dewasa bisa memilih apakah anaknya atau muriddewasa tersebut akan mengikuti pelajaran agama atau tidak. Demikian pula,mata pelajaran agama tidak menentukan kenaikan kelas, dan nilai pelajaranagama tidak dalam bentuk angka, melainkan secara kualitas dalam bentukpernyataan baik, sedang, kurang.
Neden Herkes Aşı Olmuyor? Covid-19 Aşı Tutumu ile İlişkili Değişkenler
Authors: BAŞAL Hanife , EMİR ÖKSÜZ Elif
Published: October 2022

Bu çalışmada, Covid-19 aşısına yönelik tutumları etkileyen bazı değişkenler incelenmektedir. Çalışmaya 314’ü kadın, 130’u erkek toplam 444 yetişkin katılmıştır. Olumlu ve olumsuz aşı tutumları, cinsiyete göre farklılık göstermezken, eğitim düzeyi açısından her iki tutum için de gruplar arasında anlamlı bir fark gözlenmiştir. Lisansüstü eğitim grubundaki katılımcıların olumlu aşı tutum puan ortalamaları lisans mezunu gruptan yüksek, olumsuz aşı tutum puan ortalamaları da daha düşüktür. Yaş, Sinovac ve BioNTech aşılarına güven, Covid-19 tehlikelilik ve bulaşıcılık algısı ve Covid-19 nedenlerine yönelik komplo inancının aşı tutumları ile ilişkisi çoklu regresyon analizi kullanılarak incelenmiştir. Olumlu aşı tutumlarını yordayan model toplam varyansın %49’unu açıklarken, olumsuz aşı tutumlarını yordayan modelin açıkladığı toplam varyans %42’dir. Son olarak komplo inancının eğitim düzeyi ile aşı tutumu arasındaki ilişkiye aracılık ettiği, artan eğitim düzeyinin komplo inançlarını azaltarak Covid-19 olumlu aşı tutumunu güçlendirdiği gözlemlenmiştir.
Bir Asilzadenin Çöküşü: İppolit Matveyeviç Vorobyaninov
Authors: GÜNÖR Tuğba
Published: October 2022

1928 yılında kaleme alınan On İki Sandalye adlı roman, iki önemli karakter üzerine kurgulanmış bir komedi gibi gözükmesine rağmen temelde sert eleştiriler barındıran bir hiciv romanıdır. Sovyet Rusya’sının yeni düzeni ve çarlığın silinmeyen izleriyle eserde karşımıza yepyeni bir Rusya çıkar. Bu Rusya ahlaki ve ruhsal açıdan büyük bir çöküş içerisindedir. Eser boyunca neredeyse bir tane olumlu örnek olarak gösterilecek kimse yoktur. Hepsi zaaflarının esiri olmuş insanlardır. Ancak bu kokuşmuş düzen içerisinde en büyük çöküşü, romanın başkahramanı İppolit Matveyeviç Vorobyaninov yaşar. Bir asilzade olan Vorobyaninov’un Ekim Devrimi’yle beraber tüm düzeni değişir. Kayınvalidesinin sakladığı sırrın ortaya çıkmasına kadar sakince kaderine boyun eğen Vorobyaninov, Soylular Birliği Başkanı olarak başladığı kariyerini hırsız, dilenci ve hatta katil olarak tamamlar. En sonunda elinde kalan tek şeyi olan aklını da yitirir. Temsil ettiği eski düzen gibi yok olup gider.
Revisiting the threshold effect of corruption in the link between public debt and economic growth in Nigeria
Authors: Ogbaro Eyitayo Oyewunmi , Young Ademola Obafemi , Bank-Ola Rebecca Folake
Published: October 2022

Purpose ― This study contributes to the empirical literature on the nonlinear relationship between public debt and economic growth in Nigeria using threshold regression methodology. It provides insight into how Nigeria can grow out of debt sustainably in the face of the prevailing level of corruption as an institutional indicator.
Method ― Stata's threshold command is used for data analysis, and this command fits time-series threshold models in finding the optimal number of thresholds. It does this by minimising an information criterion and using conditional least squares to estimate the parameters of the threshold regression model.
Findings ― The results show that the relationship between public debt and economic growth is nonlinear. The threshold effect of public debt on growth depends on the debt-to-GDP ratio and the level of corruption. Substantial evidence supports two threshold levels of debt-to-GDP ratio and corruption in the debt-growth nexus. The two threshold levels of corruption are 63.21 and 64.27 (on a scale of 0 to 100), with the growth effect of public debt being positive and significant in the second regime only.
Implication ― Public debt exerts significant positive effects on growth as long as corruption is kept at a moderate level. Thus, the government of Nigeria needs to ensure that corruption is pegged at a fairly moderate level that will guarantee the positive contribution of accumulated debt to economic growth.
Originality ― Unlike previous works, the study addresses the problem caused by the mechanical effect of a change in the real GDP growth rate on debt. It is based on the assumption of a maximum of two thresholds.
Does Social Media Content Affect Purchase Intention in Indonesia's Apparel Industry?
Authors: Prasetyaningtyas Sekar Wulan , Komajaya Eka Putera , Soesilo Theresia
Published: October 2022

Changes in people's behavior are impacting the increase of social media users, especially Instagram. As a visual-based social media, Instagram provides several opportunities for business owners to reach and build relationships with their target consumers through social media content. This study aims to determine the effectiveness of content shown on social media Instagram to customer engagement and purchase intention in the apparel industry in Indonesia's Jabodetabek area. This study uses a Uses and Gratification Theory (UGT) approach to explain people's motivation in using social media. The data collection method in this study uses an online questionnaire distributed to 127 active Instagram users aged 18-34 years who have seen the content of apparel products. The data analysis method in this study uses the PLS-SEM method through Smart PLS 3 software. This study result shows that the remunerative content and relational content of apparel products affect customer engagement. Moreover, customer engagement also affects the purchase intentions of apparel products. However, the vividness of content, informational content, and entertaining content of apparel products do not affect customer engagement.
A Case Study on the Use of Inquiry-Based Instruction to Improve Science Learning in Junior High Schools in Ghana
Authors: Gunu Ibrahim, Mohammed , Gomda Ayisha , Oseni Lateef Adebayo
Published: October 2022

The study examined how Inquiry-Based Learning affects students' academic progress in science lessons and whether this approach can help low-proficiency users of English to comprehend scientific concepts. The study used a Quasi-Experimental design and looked at it through the lens of Self-Determination theory. The study included a total of 40 second-year Junior High School students from two distinct classes. The research was aimed at students aged between 13 and 15 years, and therefore, only students within that age range were selected to participate. Students in the experimental group received Inquiry-Based instruction, while the control group used traditional instruction. The study lasted for four weeks and was an experimental one. To see if Inquiry-Based learning is more effective than traditional teaching, a test with 20 questions was used as a pre-test and a post-test for both the experimental group and the control group. The results of the study showed that students who were taught using an inquiry-based method scored higher than those who were taught through a traditional technique. The main finding of this study is that students in the experimental group, who had a low level of English proficiency, were able to understand the lesson without switching to their native language to explain concepts.
The Effect Of Queue Tree On Packet Loss In Bandwitch Management Online Based School Exam
Authors: Dale Wellem Wila , Hariadi Fajar , Mikaela Indri Malo Raynesta
Published: October 2022

Unequal bandwidth distribution between clients that are used for online tests will cause the quality connection among clients to differ. Especially when some client dominates the bandwidth. The other client will suffer to have a proper connection. Using Queue Tree bandwidth management with the type of Per Connection Queue (PCQ) the distribution of bandwidth can be done evenly among clients. The implementation of PCQ Queue Tree is able to reduce the length of ping time by 90% from 134 ms and 13 ms. Delay is decreased 47% from 17 ms to 9 ms with a very good category. Jitter decreased 41% from 17 ms to 7 ms with a very good category. Throughput increased 53% from 234.582 Kbps to 503.584 Kbps in the medium category. Meanwhile, in the packet loss parameter, there is no difference in conditions before and after the implementation of PCQ Queue Tree because there is no packet loss during the test, which means packet loss condition is in the very good category.
Resilience in distributed sensor networks
Authors: Ratmanski Kiril , Vecherin Sergey
Published: October 2022

With the advent of cheap and available sensors, there is a need for intelligent sensor selection and placement for various purposes. While previous research was focused on the most efficient sensor networks, we present a new mathematical framework for efficient and resilient sensor network installation. Specifically, in this work we formulate and solve a sensor selection and placement problem when network resilience is also a factor in the optimization problem. Our approach is based on the binary linear programming problem. The generic formulation is probabilistic and applicable to any sensor types, line-of-site and non-line-of-site, and any sensor modality. It also incorporates several realistic constraints including finite sensor supply, cost, energy consumption, as well as specified redundancy in coverage areas that require resilience. While the exact solution is computationally prohibitive, we present a fast algorithm that produces a near-optimal solution that can be used in practice. We show how such formulation works on 2D examples, applied to infrared (IR) sensor networks designed to detect and track human presence and movements in a specified coverage area. Analysis of coverage and comparison of sensor placement with and without resilience considerations is also performed.
A New Approach for Designing an Underbalanced Cementing Plug Using a Managed Pressure Cementing and Pump-Pull Method with Narrow Pore-Frac Pressure Window in HPHT Exploration Well: An Offshore East Kalimantan, Indonesia Case Study
Authors: Setiohadi _ , Hadistira Praja , Yudhatama Muhammad Alfianoor , Sitompul Daniel , Hutabarat Dhika Escodianto , WIharja Andre , Panjaitan Reinhard Aberson , Agriawan Crisa , Kusumawatie Reny , Wedhaswari Victoria Rasmi , Darmanto Bagus Setyo , Osman Ahmed , Azwar Cinto , Winarti Wiwin , Simanjuntak Andre
Published: October 2022

The operator was drilling their first high-pressure high-temperature (HPHT) exploration well with narrow pressure window in a swamp area of East Kalimantan. The gas field was discovered in 1977 and production started in 1990. Since then, more than 1500 wells have been drilled in this area yielding a total gas production of 9.7 Tcf. Currently T field enters established mature field status which has quite marginal reserves. Therefore, further exploration is seen as one of the solutions to locate additional reserves to enhance overall gas production. The well was drilled directionally with no offset well nearby. While drilling the 6-in open hole section, an unexpected high-pressure zone was penetrated. The zone condition was made worse by lost circulation and a high gas reading.

Two cement plugs were placed using a managed pressure cementing with pump and pull method. The first plug was set by applying surface back pressure (SBP) to maintain equivalent bottom hole pressure (BHP) between lowermost pore pressure (PP) and fracture gradient (FG) at the previous shoe. After pumping 1 m3 of cement into the annulus, pump and pull operations commenced. While performing post job circulation on the first plug, it was observed that the returned fluid density at surface was less than original mud weight, indicating the possibility of contaminant invasion from formation. After waiting for the cement to reach 500 psi compressive strength, pressure buildup was observed when annulus was shut-in, indicating an inadequate pressure seal across the cement plug

Applying lessons learned from setting the first plug, new design considerations were implemented such as increasing cement volume in the annulus to 4 m3 prior to the pump and pull operation to minimize cement overlapping risk and applying SBP at BHP near FG. A contingency plan was in place to determine the appropriate SBP value to be applied whenever the pumping rate was changed. A second plug job was performed safely and flawlessly by achieving the top of cement as desired. A successful inflow test was performed with indication of no contaminant invasion nor pressure bypass around the cement plug. The rig was able to continue its next operation to sidetrack the well.

This paper presents the design considerations, methodology applied, and lessons learned two managed pressure cement plugs using pump and pull method in a well bore with a narrow pore-frac window where the new techniques were implemented to enhance success of the plug job despite the complexity and risk inherent with an underbalanced operation.
Effects of dietary habits and catheterization type on breast cancer-related lymphedema: a retrospective cohort study
Authors: Wang Ling , Zhen Meixin , Li Hui , Yan Huang , Jiang Botao , Wiley James A. , Chen Xuemei , Yv Jun , Ding Boni , Yang Dongliang
Published: October 2022

Background Understanding the factors that contribute to variability in breast cancer-related lymphedema (BCRL) is an important first step in developing targeted interventions to improve quality of life in breast cancer patients. Although previous research studies have has identified many risk factors for BCRL, dietary habits and catheterization type have rarely been studied until the present.This study aims to explore the effects of dietary habits and catheterization type on BCRL.
Methods This study included 1,476 breast cancer patients after surgery between January 1, 2010 and September 1, 2020. Lymphedema was assessed with a validated self-reported questionnaire. All research data was obtained by medical records and follow-up database. Survival analysis was conducted to explore the effects of dietary habits and catheterization type on BCRL.
Results The result showed an increased risk for BCRL among breast cancer patients who followed a high-fat diet pre-hospitalization (hazard ratio [HR] =2.473; P<0.001), indwelling totally implantable venous access ports (TIVAPs) compared with indwelling needle (HR=0.558; P=0.017) and indwelling TIVAPs, compared with anindwelling peripherally inserted central catheter (PICC) (HR=0.691; P=0.086).
Conclusion High-fat diet pre-hospitalization was an independent risk factor for lymphedema. The TIVAPs did not exert a protective effect on lymphedema compared with the PICC and indwelling needle. This study finding offers new insights to develop targeted interventions to decrease the incidence of lymphedema.
Polypharmacy in patients with chronic liver disease: a systematic review of definitions
Authors: Danjuma Mohammed I , ansari soubiya , Abu-Affifeh Leen Maen , Altikrity Nawras , Al-Sr Aisha , Jumbo Unwam , Naseralallah Lina
Published: October 2022

Background

Despite its central role in drug metabolism, there is still residual uncertainty regarding the rising burden as well as exact definition of polypharmacy in patients with chronic liver disease.

Methods

We carried out a systematic search of EMBASE, PUBMED, Cochrane Database of Systematic Reviews, Science Citation Index, and Database of Abstracts of Reviews of Effects (DARE) between 1st January 2000 and 30th January 2022 for studies exploring polypharmacy in patients with chronic liver disease. We excluded studies that had no explicit numerical or descriptive definition of polypharmacy.

Results

We retrieve (N = 171) reports from systematic literature search with six studies (N = 918 548 patients) meeting criteria for inclusion in the review. A total of (N = 8) iterations of polypharmacy definitions were retrieved with numerical definitions (≥ 5 medications) constituting up about 62.5% of this. The latter is the most reported definition of polypharmacy. Two studies described polypharmacy based on the duration of exposure. None of the reviewed studies examined the constituent of polypharmacy (i.e., whether liver-related or non-liver related medications).

Conclusion

In a systematic review of current reports on medication counts in patients with chronic liver disease, we found an intake of 5 or more medications as consistent with the definition of polypharmacy in this patient cohorts. It remains uncertain if adoption of “non-liver related polypharmacy” as a definition will best characterize this therapeutic morbidity in these cohorts of patients.
Prospero Number: CRD42022306572
Study on the variation of MeHg content in different types of soils in non-ferrous metallurgical areas
Authors: Xinyu Li , Dongmei Zheng , Yuqi Wang , Xiaoxiao Xu
Published: October 2022

To study the methylation of mercury in soils of various utilization categories in typical non-ferrous metallurgical areas, soils of various utilization categories were selected for the experiment, and the changes of soil mercury, methylmercury, and SRB content were analyzed, whether the changes of SRB and the changes of soil physical and chemical properties affected the formation of methylmercury, and the results showed that: with the incubation time increased, the mercury content showed a decreasing-increasing-reducing trend. Except for the riverbank substrate, the MeHg content of the other five different land-use types exhibited a trend of rising and then falling, and the MeHg content of soils under flooded conditions was higher than that of non-flooded soils. SRB was present in all types of soils and promoted soil Hg methylation in the late incubation period. Among soil physical and chemical properties, pH and soluble sulfide were significantly correlated with MeHg content in some soils, indicating that MeHg formation was related to SRB, pH, and soluble sulfide, which is important for the study of different types of soils in non-ferrous metallurgical areas.
Association of discordance between Anti-Müllerian Hormone (AMH) and antral follicle count (AFC) with obesity in in vitro fertilization patients: a retrospective cohort study
Authors: Chen Yannan , Gu Xiaoling , Guan Xi , Yu Minyan , Zhong Shuping , Yang Panpan , Wang Xia , Wang Di
Published: October 2022

Background: Both anti-Mullerian hormone (AMH) and antral follicle count (AFC) predict ovarian reserve independently and have been shown to correlate well. However, it is quite common to encounter discordance between the two clinical indices. This objective of this study is to speculate which condition is favorable to patients and to decide what best to be done in cases of such discordance.
Methods: This retrospective cohort study analyzed the medical records of 714 women undergoing the first IVF cycle at the Center for Reproductive Medicine, the Affiliated Hospital of Nantong University, Nantong, Jiangsu between January 2017 and December 2020. All patients had their essential characteristics, baseline FSH, Estradiol, PRL, LH, Testosterone, CA125, AMH, and AFC recorded. Patients were classified into three groups according to whether their AMH and AFC values were in the lower quartile, upper quartile, or in between, namely Group A (Concordance, concordant in AMH and AFC), Group B (HTP, AMH concentration higher than predicted according to AFC) and Group C (LTP, AMH concentration lower than predicted according to AFC). SPSS 25.0 software package (SPSS, Inc., Chicago, IL, USA) was used for statistical analysis.
Results: The entire study population has a good concordance between AMH and AFC. 240 women (33.61%) had discordant AMH and AFC values, and the proportion in Group B(HTP) and Group C(LTP) seemed similar (16.67% VS 16.94%). The three cohorts had similar age, infertile duration, FSH, Estradiol, PRL, LH, Testosterone, and CA125 levels. BMI progressively increased from Group B to Group A and to Group C. The ratio of patients, who had completely mature oocytes (COM), rapidly decreased from Group C to Group A and to Group B. Although no significant difference in CMO rate was observed among Group A, B, and C when stratified according to BMI, CMO rate was the highest (72.31%) when BMI< 18.5 kg/m2 in all BMI categories.
Conclusions: Our analysis demonstrated a high frequency of clinical discordance between AMH and AFC in women undergoing IVF therapeutic regime. Patients’ BMI and completely mature oocytes ratio are significantly different among distinct grouping based on their AMH and AFC partition.
Effects of moisture content and landfill age on the shear strength properties of municipal solid waste in Xi'an, China
Authors: Huang Menghe , Zhang Zhenying , Lan Jiwu , Zhang Jiahe , Xu Hui
Published: October 2022

As waste landfills continue to expand, accidents can occur if these landfills are not properly stabilized. In this study, samples of municipal solid waste (MSW) from a waste landfill in Xi'an, China were collected through on-site drilling. Considering the effects of eight landfill ages (1, 2, 3, 11, 12, 13, 21, 22, and 23 y) and six moisture contents (natural, 20, 40, 60, 80, and 100%), 324 groups of MSW were tested in the laboratory with a direct shear test apparatus. The results indicate the following: (1) with an increase in horizontal shear displacement, the shear stress of MSW gradually increases without a peak stress phenomenon, which is a displacement hardening curve; (2) with an increase in landfill age, the shear strength of MSW increases; (3) with an increase in moisture content, the shear strength of low-age MSW first increases and then decreases, but the relationship between shear strength and moisture content of medium- and high-age MSW is not significant; (4) with an increase in landfill age, the cohesion (c) decreases, and the internal friction angle (φ) increases; (5) with an increase in moisture content, the c and φ of low-age MSW first increases and then decreases. Based on these results, a shear strength, landfill age, and moisture content correlation model is established, and the model has a high degree of fit with the overall experimental data. The results of this study can provide a reference for the stability calculations of MSW landfills.
The effect of motivational interviewing and/or cognitive behaviour therapy on gestational weight gain – a systematic review and meta-analysis
Authors: Nightingale Helen , Mnatzaganian George , Hooker Leesa , Barrett Stephen , Kingsley Michael
Published: October 2022

Background
Women with insufficient or excessive weight gain in pregnancy are at risk of adverse perinatal outcomes. Motivational interviewing and/or cognitive behaviour therapy have demonstrated efficacy in initiating and sustaining behaviour change, including weight control. The objective of this review was to investigate the effect of antenatal interventions that include components of motivational interviewing and/or cognitive behaviour therapy on gestational weight gain.
Methods
Five electronic databases were systematically searched to March 2022. Randomised controlled trials evaluating interventions with identified components of motivational interviewing and/or cognitive behaviour therapies were included. Pooled proportions of appropriate and inappropriate gestational weight gain, and standardised mean difference for total gestational weight gain, were calculated. Grades of Recommendation, Assessment, Development and Evaluation approach was used to evaluate the quality of evidence.
Results
Twenty-one studies (8030 participants) were included. Overall, the intervention limited total gestational weight gain (-0.18 kg, 95% confidence interval: -0.27 to -0.09 kg) and improved the proportion of women achieving recommended gestational weight gain (29% versus 23%, p < 0.001), but the evidence is very uncertain. The magnitude of effect was greater in women with overweight or obesity when compared to women with BMI < 25 kg/m2.
Conclusion
Motivational interviewing and/or cognitive behaviour therapy techniques might be effective for promoting healthy gestational weight gain. Nevertheless, a high proportion of women do not achieve recommended gestational weight gain. Future interventions should consider factors, including user perspectives, in the design and delivery of psychosocial interventions that aim to support healthy gestational weight gain.
Study registration:
The protocol for this review was registered with the PROSPERO International register of systematic reviews (registration number CRD 42020156401).
Effectiveness of Deprescribing Interventions in Older Adults: An Overview of Systematic Reviews
Authors: Chua Shiyun , Todd Adam , Reeve Emily , Smith Susan M , Elsisi Zizi , Hughes Stephen , Husband Andrew , Huang Yuhan , Harris Jeffrey R , Devine Beth , Gray Shelly
Published: October 2022

Background: Rigorous evidence to guide deprescribing is limited, and priorities to inform deprescribing research and practice remain unclear. The objective of this overview of systematic reviews (i.e. reviews) was to synthesize the available review evidence regarding the effectiveness of interventions to deprescribe medications in older adults.
Methods
11 databases were searched from January 2005 to October 2020. We included randomized or non-randomized controlled designs. Two independent reviewers screened and extracted data. We synthesized results in two steps: Step 1 identified results as reported by the original review (including meta-analyses) and Step 2 involved a narrative synthesis of reviews by outcome. Pre-specified subgroups included patient characteristics (e.g., dementia, frailty, advanced age), intervention type and setting. Outcomes included medication-related outcomes (e.g., medication reduction, potentially inappropriate medications) or other outcomes(e.g., mortality, adverse effects, falls, cognition, hospitalizations, quality of life, costs, surrogate biomarkers). Assessment of Multiple Systematic Reviews 2 was used to assess quality of reviews.
RESULTS: 2,335 unique citations were retrieved, of which 93 full-text articles were assessed for eligibility. 33 reviews (encompassing 13 meta-analyses) were included. 19 of the 33 reviews had a general deprescribing focus, 13 focused on specific medication classes or therapeutic category and one review included both. Ten of 13 reviews meta-analyzed medication-related outcomes (29 outcomes: 21 favored the intervention, seven reported no difference and one favored the comparison). The narrative synthesis indicated that most interventions resulted in some evidence of medication reduction. Few meta-analyses reported on other outcomes, and our narrative synthesis found primarily mixed effects or no evidence of an effect on these outcomes. Limited information was available for patient characteristic subgroups. All reviews scored low or critically low on quality assessment.
CONCLUSIONS: Deprescribing interventions likely resulted in medication reduction. Information about other outcomes was not routinely examined, and where included, studies were likely underpowered. The evidence, though of low quality, suggests deprescribing was not associated with increased adverse events, and had little evidence of effect on mortality, quality of life and health-care use. Future research should focus on designing studies powered to examine harms, patient-centered outcomes and the effects on vulnerable subgroups.
Systematic Review Registration
PROSPERO CRD42020178860
This study was supported by NIA (1R24AG064025).
Hydrochemistry; Compliance And Comparative Case Study of Public Water Works In Enugu And Ebonyi States, Southeast of Nigeria
Authors: J Okenwa C. , P Ikeyi A. , N Owoh E. , E Chinyere E. , C Nnonah C. , onunze Emmanuel. C.
Published: October 2022

The compliance and comparative case study of public water works in Enugu and Ebonyi State of Nigeria was carried out in this study. The water samples were collected at Ajali water treatment plant Enugu State (Sample A), 9 Works road GRA, Enugu State (Sample B), Ezilo water Scheme Ebonyi State (Sample C) and Ameke in Ezilo Ebonyi State (Sample D). Ten physicochemical parameters and water like- metals such as SO42−, Cl−, NO3, Mg2+, Ca2+, Na+, Pb, Ni, Cr, and Al were determined in rainy season in for one year. The results shows that chloride (Cl−), (A = 97 mg/l, B = 121 mg/l, C = 97 mg/l, D = 119 mg/l); nitrate, (A = 3.11 mg/l, B = 1.29 mg/l, C = 1.10 mg/l, D = 0.70 mg/l); total phosphate, (A = 1.97 mg/l, B = 0.26 mg/l, C = 0.32 mg/l, D = 0.42 mg/l); Biological oxygen demand (BOD), (A = 0.25 mg/l, 6.00 mg/k, C = 1.10 mg/l, D = 7.40 mg/l); Chemical oxygen demand (COD), (A = 50.67 mg/l 10.67 mg/l, C = 30.39 mg/l, D = 26.67 mg/l); Electrical conductivity (EC), (A = 100 µs/cm, B = 30 µs/cm, C = 200 µs/cm, D = 250 µs/cm); and pH, (A = 7.60, B = 6.62, C = 5.50, D = 5.90) mostly conform to the WHO set standard for drinking water. While TS, TDS, and TSS were (A = 205, B = 535, C = 151, D = 183 mg/l), (A =,60 B = 555, C = 121, D = 128 mg/l) and (A = 145, B = 280, C = 30, D = 55 mg/l) respectively. Further more, the results of the heavy metal analysed showed that; Lead (Pb) was not detected in all water samples; Nickel (Ni) was observed to be 0.07 mg/l in the water sample collected from Sample A; Sample B contained 0.03 mg/l; Sample C not detected while in Sample D, it was 0.04 mg/l;. Chromium (Cr) was observed to be 0.01 mg/l in Sample A, it was not detected in both water samples B and C but was 0.02 mg/l in Sample D; which means that all the water samples studied conform to the WHO set standard for chromium in drinking water. Aluminium (Al) was observed to be 0.05 mg/l, 0.01 mg/l, Not detected and 0.03 mg/l in water sample A, Sample B, Sample C and Sample D. There is a variation in the Mg2+ in Ebonyi water. Hpwever, It was observed that the physical parameters of the water samples analysed were within the World Health Organisation (WHO) set standard for drinking water.
Development of Real-time PCR Method for Detection and Quantification of the Coral Pathogenic Strain XSBZ14
Authors: Zhang Na , Yang Siyue , Zhang Xiang , Long Hao , Cai Xiaoni , Fu Yanan , Xie Zhenyu
Published: October 2022

Purpose
Coral degradation is a worldwide ecological problem. Bacterial diseases are a great danger to coral health. However the bacterial communities in coral reef ecosystems are complex and variable. Therefore, real-time and accurate detection of coral pathogenic bacteria is necessary. This study aims to develop a detection method for pathogenic bacteria Vibrio alginolytcus XSBZ14, which could cause Porites andrewsi white syndrome (PAWS), is an enormous threat to coral reef ecosystem in the South China Sea. That could provide help for the protection of coral reefs in the South China Sea.
Methods
At first, a low sequence identity single-copy sequence S2 was selected from the genome by in-house perl script. Using the designed specific primers, four different types of standard curves were subsequently plotted for the accurate quantification of the strain XSBZ14 in four different samples (DNA, bacterial suspension, coral tissue, seawater). Then, using the strain to infect the Galaxea fascicularis and test the strain in the coral culture water during the week.
Results
The rapid detection method of pathogenic bacteria by RT-PCR was established. The limit of detection (LOD) of the RT-PCR was 0.88 pg/reaction (0.44 pg/µL) in DNA, 2 CFU/reaction (1000 CFU/mL) in bacterial suspension, 2 CFU/reaction in coral tissue, 20 CFU/reaction in seawater for the strain XSBZ14, respectively. In addition, according to the detection results of the RT-PCR, the strain XSBZ14 could survive in Galaxea fascicularis for a week, and the strain could also be detected from its reared seawater.
Conclusion
These results indicated that other coral species and their habitats might act as an important reservoir for the strain XSBZ14 and mediated its horizontal transmission in coral reefs. In a word, the RT-PCR detection method of a coral pathogenic strain XSBZ14 was firstly established. The method is a robust tool for the rapid detection and quantification of the coral pathogen, XSBZ14, and is very useful for PAWS epidemiological survey and specific pathogen-free coral transplantation in the South China Sea.
Prognostic effect of albumin-to-alkaline phosphatase ratio on patients with hepatocellular carcinoma: a systematic review and meta-analysis.
Authors: Zhang Xinyuan , Xin Yujing , Yang Yi , Chen Yi , Zhou Xiang
Published: October 2022

Background
The prognostic value of albumin-to-alkaline phosphatase ratio (AAPR) in patients with hepatocellular carcinoma (HCC) remains controversial. This meta-analysis aims to evaluate the prognostic role of AAPR in patients with HCC.
Methods
The databases of Web of Science, Embase, Cochrane Library and PubMed were comprehensively searched from inception to April 25, 2022. Pooled hazard ratio (HR) and 95% confidence interval (CI) were calculated with Stata 16.0 software for the assessment of the relationship between AAPR and overall survival (OS) as well as disease-free survival (DFS) in patients with HCC.
Results
A total of 2634 patients from 12 cohorts were included in this meta-analysis. The pooled results showed that lower AAPR was significantly associated with poorer OS (HR: 2.02, 95% CI: 1.78–2.30). Similarly, pooled results demonstrated that lower AAPR was also significantly associated with poorer DFS (HR: 1.61, 95% CI: 1.36–1.92). Heterogeneity for DFS and publication bias for OS existed, however, the subgroup analysis, meta-regression analysis as well as adjustment using trim-and-fill analysis confirmed a stable interaction between AAPR and OS as well as DFS.
Conclusions
This meta-analysis proves that lower AAPR was significantly associated with poorer OS and DFS in patients with HCC, and AAPR could be a promising indicator for prognosis of HCC.
Retina-inspired controllable neuromorphic vision organic sensors with ultraweak ultraviolet detection
Authors: Ji Deyang , Jiang Ting , Wang Yiru , Zheng Yingshuang , Wang Le , He Xiang , Deng Yunfeng , Dong Huanli , Li Liqiang , Tian Hongkun , Geng Yanhou , Xie Linghai , Ling Haifeng , Hu Wenping
Published: October 2022

Sensing and recognizing invisible ultraviolet (UV) light is vital for exploiting advanced artificial visual perception system with tetrachromacy. However, due to the uncertainty of the natural environment, the UV signal is very hard to be detected and perceived. Here, we report a controllable UV-ultrasensitive neuromorphic vision sensor (NeuVS) that uses organic phototransistors (OPTs) as working unit to integrate sensing, memory and processing functions. Benefiting from asymmetric molecular structure and unique UV absorption of the active layer, the as fabricated UV-ultrasensitive NeuVS can detect the illumination intensity of 370 nm UV-light as low as 31 nw cm-2 and exhibit one of the best optical figures of merit in UV-sensitive neuromorphic vision sensors. Furthermore, the NeuVS array exbibits good image sensing and memorization capability due to its ultrasensitive optical detection and large density of charge trapping states. In addition, the wavelength-selective response and multi-level optical memory properties are utilized to construct an artificial neural network (ANN) for extraction and identification of invisible UV information. The NeuVS array can extract UV handwritten digit from the original color image by filtering red, green and blue (RGB) noise, and significantly improve the recognition accuracy from 46% to 90%.