bluuebunny/crossref_metadata_2025 huggingface dataset:
Arbuscular Mycorrhizal Fungi Associated with Myrciaria dubia in the Amazonia Region, Peru
Authors: Pineda-Lázaro Alexandra Jherina , Vallejos-Tapullima Adela , Hernández-Amasifuen Angel David , Carballar-Hernández Santos , Imán-Correa Sixto , Carvajal-Vallejos Fernando Marcelo , Ríos-Ramírez Orlando , Corazon-Guivin Mike Anderson
Published: January 2024

Myrciaria dubia (Kunth) McVaugh (camu‐camu) is a shrub native to the Amazon region that produces fruits with a high content of vitamin C and various bioactive compounds, making it a functional food with antioxidant, anti‐inflammatory, and antimicrobial properties. However, it is unknown which microorganisms are associated with its root system and can influence its growth and productivity. Arbuscular mycorrhizal fungi (AMF) are associated with most plants and are essential for their establishment, survival, and productivity since they facilitate their nutrition, increase water absorption, and improve soil structure. Although the AMF association is already known in some species of Myrciaria, no report is available on its association in M. dubia. This study presents, for the first time, the symbiotic association between AMF and M. dubia from the INIA San Roque experimental station located in the Amazon region, Peru. For the morphological and molecular analyses of the AMF, samples of rhizospheric soil and roots from two native accessions of the National Germplasm Bank of M. dubia were collected. Eighteen AMF morphospecies were identified in rhizospheric soil, belonging to nine genera Acaulospora, Ambispora, Entrophospora, Diversispora, Gigaspora, Glomus, Paraglomus, Funneliformis, and Sclerocystis, being the first one the most frequent. The roots of M. dubia showed high colonization by AMF (mean = 91%), and characteristic structures of arbuscular mycorrhizae, such as vesicles, hyphae, and arbuscules, could be observed. Likewise, the molecular analysis detected the presence of genetic material (rDNA) corresponding to AMF in the roots of both accessions. Our results evidenced the symbiotic association between AMF and M. dubia, which encourages further investigation of the functional potential of these microorganisms in this economically crucial agricultural plant in Peru.
Table S4 from The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
Authors: Klein David C. , Lardo Santana M. , Hainer Sarah J.
Published: January 2024

Table S4. Genomic coordinates and normalized signal over curated myeloid gene-distal DHSs for all CUT&RUN experiments.
Supplementary Figure 4 from The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
Authors: Klein David C. , Lardo Santana M. , Hainer Sarah J.
Published: January 2024

BRD9 inhibition leads to reduced chromatin accessibility at mRNA TSSs
FIGURE 6 from The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
Authors: Klein David C. , Lardo Santana M. , Hainer Sarah J.
Published: January 2024

ncBAF maintains accessible chromatin at gene-distal regulatory elements bound by hematopoietic TFs. A, Volcano plot depicting selected motifs with altered ATAC-seq footprints after BRD9 inhibition. All cell lines were merged for this analysis (n = 10 per condition). B, Analysis of published AML core circuit factor ChIP-seq data from PRJNA751732 (102), visualized over bromodomain-dependent ATAC-seq peaks. All experiments were performed in the MV-4-11 cell line. Average values of two to three independent replicates are shown in each heat map. C, Proposed model of ncBAF-mediated hematopoietic TF regulation.
FIGURE 5 from The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
Authors: Klein David C. , Lardo Santana M. , Hainer Sarah J.
Published: January 2024

Myc expression in AML is dependent on BRD9-mediated enhancer interaction. Genome browser track depicting ncBAF complex occupancy, H3K27ac localization, chromatin accessibility, and nascent transcription at the Myc genomic locus and the AML-specific Myc superenhancer BENC. Changes in chromatin accessibility after 6-hour BRD9 inhibition mirror those caused by prolonged inhibition of BAF complex ATPases (8). n = 2 replicates per track (averaged). ATAC-seq tracks marked with an asterisk (*) are from GSE190722. All experiments shown were performed in the MV-4-11 cell line and are consistent with other cell lines. See Supplementary Fig. S7 for ML-1 cell line data.
FIGURE 2 from The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
Authors: Klein David C. , Lardo Santana M. , Hainer Sarah J.
Published: January 2024

The BRD9 bromodomain regulates transcription of AML- and hematopoiesis-associated genes. A, Volcano plot depicting DESeq2 results from TT-seq experiments in Kasumi-1, KG-1, ML-1, MV-4-11, and U937 AML cell lines, analyzed together. Fold changes are shown as effect after 6-hour treatment with 10 µmol/L I-BRD9, relative to vehicle (1% DMSO). Significance cutoffs of adj. P < 0.05 and log2 fold change > 1 are indicated by dashed lines. n = 2 replicates per drug condition and cell line, for a total of 20 experiments. Browser tracks depicting transcription of the Ccr2 (B) and Ccl2 (C) genes. n = 2 replicates per condition and cell line, averaged. TPM values of the FDA-approved AML chemotherapy target Bcl2 (D) and p53-related tumor suppressor gene Ppp1r13b (E). Arrows link the same replicate between conditions. n = 2 replicates per drug condition and cell line, for a total of 20 experiments. Significance was assessed using paired two-tailed t tests. F, Heatmap depicting log2 fold change of TPM values after 6-hour I-BRD9 treatment for 23 genes defined as significantly mutated in AML per TCGA guidelines (118). n = 2 replicates per condition and cell line.
A Witteveen-Kolk Syndrome Patient with Reflux Disease and a de novo Deletion of the SIN3A Gene
Authors: Uctepe Eyyup , Kandemir Nefise , Bir Firdevs Dinçsoy , Karhan Asuman Nur , Tumer Sait , Ondes Emine Busra , Konuskan Bahadır , Yesilyurt Ahmet
Published: January 2024

Introduction: The Witteveen-Kolk syndrome (WITKOS) (OMIM: 613406) is a heterogeneous emerging disorder caused by pathogenic variants or microdeletions encompassing the SIN3A gene (SIN3 Transcription Regulator Family Member A). It is characterized by distinctive facial features, developmental delay, intellectual disability, microcephaly, short stature, and subtle anomalies on brain magnetic resonance imaging (MRI). To date, about 50 patients have been reported in the medical literature. Patient Presentation: In this article, we reported a patient with classic findings of WITKOS including global developmental delay, microcephaly, hypotonia, vomiting, malnutrition, autistic and dysmorphic facial features, and cardiac abnormalities. Also, a barium esophagogram suggested severe motility disorder and gastroesophageal reflux disease. Affymetrix CytoScan 750K microarray showed a de novo 1.6-Mb deletion at 15q24.1q24.2, including the whole SIN3A gene. We have also summarized the clinical features of WITKOS patients in the medical literature and cardiac abnormalities detected in 4 out of 10 patients in studies that clearly state that cardiac examination was performed in the patients. Conclusion: Our findings showed that cardiac defects are not uncommon findings in WITKOS. Physicians should also be aware of reflux disease and motility disorder in patients with feeding difficulty together with early cardiac examination in terms of an improved quality of life in WITKOS patients.
Feasibility of Simultaneous Bilateral Endoscopic Surgery in Prone Split-Leg Position for Bilateral Upper Urinary Tract Calculi: A Pilot Study
Authors: Jiang Yihang , Sheng Yali , Zhang Junhui , Jiang Yuguang , Shan Hui , Kang Ning
Published: January 2024

Introduction: We explored the viability of simultaneous bilateral endoscopic surgery (SBES) in the prone split-leg position for managing bilateral calculi. Methods: We retrospectively reviewed 72 patients who underwent SBES, with procedures involving ureteroscopy (URS) and contralateral percutaneous nephrolithotomy (PNL) simultaneously, in prone split-leg position. Results: Operative times averaged 109.38 ± 30.76 min, with an average hospital stay of 7.79 ± 3.78 days. The bilateral stone-free rate (SFR) was 70.83%, while URS and PNL demonstrated comparable unilateral SFR (83.33% and 79.17%, respectively). Receiver operating characteristics curves for predicting unilateral residual fragments yielded an area under the curve of 0.84 (URS) and 0.81 (PNL) with respective cutoff values of stone diameter of 11.55 mm and 23.52 mm. Fifty-seven (79.17%) and 15 (20.83%) patients encountered grade 0–1/2 complications, with no severe complications (grade 3–5) recorded. No significant changes in blood count or renal function were observed post-SBES. Conclusions: SBES in the prone split-leg position is a viable option for managing bilateral upper tract urolithiasis. Larger scale studies are needed to further assess safety and efficacy in various positions.
O céu que nos envolve: introdução à astronomia para educadores e iniciantes
Authors:   Universidade de São Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Picazzio Enos
Published: January 2024

O céu intriga o homem desde a pré-história, representado em pinturas anteriores à escrita e em mitos sobre deuses e heróis. Não tardou até que começássemos a tentar entendê-lo. A astronomia nasceu de observações ainda a olho nu e de hipóteses que nem sempre se mostraram verdadeiras. Da Mesopotâmia à América, os primeiros estudos do céu tiveram impacto em diversos aspectos de cada cultura, desde a religião até a divisão e a organização do tempo. Ainda hoje, a astronomia continua a nos desafiar. Os capítulos desta obra foram escritos por astrônomos com vasta experiência em pesquisa, ensino e divulgação, estão organizados para atender a interesses específicos, aprofundando cada tema de forma particularizada. No entanto, este livro também pode ser lido como uma jornada. Partimos do modo como nos relacionamos com a astronomia – desde o que ela representou e o que representa ao homem até os modos como observamos e estudamos o céu. Caminhamos por suas implicações para nosso planeta e para o Sistema Solar, com a combinação de fúria e harmonia essencial para sua formação e seu funcionamento. Viajamos em direção às estrelas e às galáxias, até lançarmos nosso olhar ao Universo – sua história, sua composição e a Teoria do Big Bang, com seu embasamento teórico e observacional. E encerramos o percurso voltando a uma questão essencial: a vida, e como ela poderia se manifestar no Universo. O objetivo desse material é levar um pouco do Universo aos estudantes brasileiros, integrando um trabalho que vem sendo realizado no Departamento de Astronomia do Instituto de Astronomia, Geofísica e Ciências Atmosféricas da USP há algumas décadas.
Preeclampsia-Associated Cardiovascular Risk Factors 6 Months and 2 Years After Pregnancy: The P4 Study
Authors: Henry Amanda , Mangos George , Roberts Lynne M. , Brown Mark A. , Pettit Franziska , O’Sullivan Anthony J. , Crowley Rose , Youssef George , Davis Gregory K.
Published: January 2024

BACKGROUND:

Increased cardiovascular risk following preeclampsia is well established and there are signs of early cardiovascular aging 6 months postpartum. This study assessed whether blood pressure (BP) and other cardiovascular measures are abnormal 2 years postpartum in the same cohort to determine ongoing risk markers.

METHODS:

Six months and 2 years postpartum, BP was measured using sphygmomanometry, 24-hour ambulatory BP monitoring, and noninvasive central BP. Anthropometric measures, blood, and urine biochemistry were performed. Cross-sectional comparisons between preeclampsia and normotensive pregnancy (NP) groups and longitudinal comparisons within each group were made at 6 months and 2 years.

RESULTS:

Two years postpartum, 129 NP, and 52 preeclampsia women were studied who also had 6 months measures. At both time points, preeclampsia group had significantly higher BP (office BP 2 years, 112±12/72±8 versus 104±9/67±7 mm Hg NP; [
P
<0.001]; mean ambulatory BP monitoring 116±9/73±8 versus 106±8/67±6 mm Hg NP; [
P
<0.001]). No significant BP changes noted 6 months to 2 years within either group. Office BP thresholds of 140 mm Hg systolic and 90 mm Hg diastolic classified 2% preeclampsia and 0% NP at 2 years. American Heart Association 2017 criteria (above normal, >120/80 mm Hg) classified 25% versus 8% (
P
<0.002), as did our reference range threshold of 122/79 mm Hg. American Heart Association criteria classified 60% post-preeclampsia versus 16% after NP with above-normal ambulatory BP monitoring (
P
<0.001). Other cardiovascular risk markers more common 2 years post-preeclampsia included higher body mass index (median 26.6 versus 23.1,
P
=0.003) and insulin resistance.

CONCLUSIONS:

After preeclampsia, women have significantly higher BP 6 months and 2 years postpartum, and have higher body mass index and insulin-resistance scores, increasing their future cardiovascular risk. Regular cardiovascular risk screening should be implemented for all who have experienced preeclampsia.
Parabiosis Discriminates the Circulating, Endothelial, and Parenchymal Contributions of Endogenous Tissue-Type Plasminogen Activator to Stroke
Authors: Furon Jonathane , Lebrun Florent , Yétim Mervé , Levard Damien , Marie Pauline , Orset Cyrille , Martinez de Lizarrondo Sara , Vivien Denis , Ali Carine
Published: January 2024

BACKGROUND:

Intravenous injection of alteplase, a recombinant tPA (tissue-type plasminogen activator) as a thrombolytic agent has revolutionized ischemic stroke management. However, tPA is a more complex enzyme than expected, being for instance able to promote thrombolysis, but at the same time, also able to influence neuronal survival and to affect the integrity of the blood-brain barrier. Accordingly, the respective impact of endogenous tPA expressed/present in the brain parenchyma versus in the circulation during stroke remains debated.

METHODS:

To address this issue, we used mice with constitutive deletion of tPA (tPA
Null
[tPA-deficient mice]) or conditional deletion of endothelial tPA (VECad [vascular endothelial-Cadherin-Cre-recombinase]-Cre
∆tPA
). We also developed parabioses between tPA
Null
and wild-type mice (tPA
WT
), anticipating that a tPA
WT
donor would restore levels of tPA to normal ones, in the circulation but not in the brain parenchyma of a tPA
Null
recipient. Stroke outcomes were investigated by magnetic resonance imaging in a thrombo-embolic or a thrombotic stroke model, induced by local thrombin injection or FeCl
3
application on the endothelium, respectively.

RESULTS:

First, our data show that endothelial tPA, released into the circulation after stroke onset, plays an overall beneficial role following thrombo-embolic stroke. Accordingly, after 24 hours, tPA
Null
/tPA
Null
parabionts displayed less spontaneous recanalization and reperfusion and larger infarcts compared with tPA
WT
/tPA
WT
littermates. However, when associated to tPA
WT
littermates, tPA
Null
mice had similar perfusion deficits, but less severe brain infarcts. In the thrombotic stroke model, homo- and hetero-typic parabionts did not differ in the extent of brain damages and did not differentially recanalize and reperfuse.

CONCLUSIONS:

Together, our data reveal that during thromboembolic stroke, endogenous circulating tPA from endothelial cells sustains a spontaneous recanalization and reperfusion of the tissue, thus, limiting the extension of ischemic lesions. In this context, the impact of endogenous parenchymal tPA is limited.
The molecular mechanisms underlying gut microbiota-miRNA interaction in metabolic disorders
Authors: Prukpitikul P. , Sirivarasai J. , Sutjarit N.
Published: January 2024

Metabolic disorders are a major global health problem. Gut microbiota not only affect host metabolism through metabolites, inflammatory processes, and microbial-derived extracellular vesicles, but they also modulate the host microRNA, which may impact the host metabolism. Hence, the underlying mechanisms between gut microbiota-microRNA interaction can potentially be a novel alternative strategy for treating metabolic disorders. This review aims to give an update on the latest evidence and current knowledge of the underlying mechanisms of gut microbiota-miRNA interaction, focusing on metabolic homeostasis. Gut microbiota mainly communicate with host microRNA through lipopolysaccharide and secondary microbial metabolites. These signalling messengers circulate around the metabolic organs and modify gene expression through microRNA interference. Interestingly, while intestinal microRNAs play a vital role in both intestinal barrier and gut microbiota homeostasis, the presence of gut microbiota is also required for the proper functioning of intestinal microRNAs, suggesting a cooperative mechanism in intestinal health. Although the correlations between gut microbiota and microRNA have been observed in both mice and humans, a causal relationship should be confirmed. Moreover, further investigation is needed to provide more evidence of a gut microbiota-microRNA interaction to support the possibility of using that axis as a novel therapeutic target to treat metabolic disorders.
The Folly of Deception: Proverbs 26:24–28, Falsification of Results, and the National University Commission in Nigeria
Authors: Uroko Favour C.
Published: January 2024

This study is a theological reflection on Proverbs 26:24–28 and its relevance to the National Universities Commission’s accreditation exercises in Nigerian universities. Existing literature has not adequately looked into the corruption going on between the nuc and universities in Nigeria. In this study, we extended the literature in this area. The nuc usually earmarks periods to visit universities to appraise their infrastructure and manpower capacity. The aim was to ensure that funding for Nigerian universities was judiciously used. Unfortunately, when nuc officials visit universities, they are bribed into writing down in their reports the pass mark for departments and units that are not qualified to have a pass mark. Also, lectures and departmental heads go as far as borrowing classrooms and offices and putting up tags just to escape the accreditation process. This has greatly added to the sorry state of Nigerian universities. A literary analysis was employed. Recommendations were proffered.
Anthropogenic Contribution to the Unprecedented 2022 Midsummer Extreme High-Temperature Event in Southern China
Authors: Cao Chenyu , Guan Xiaodan , Li Chao , Gao Zhaokui , Gu Tonghui
Published: January 2024

Anthropogenic influence contributed approximately 61% to the extreme high-temperature event in southern China in midsummer 2022, according to a dynamic adjustment methodology and supported by optimal fingerprinting analysis of CMIP6 models.
Sacramental Action in Response to “Urban Crisis”: An Incarnational Critique of the General Convention Special Program
Authors: Scott Felder Ryan
Published: January 2024

In 1967, the General Convention Special Program (GCSP), led by Presiding Bishop Hines, emphasized unconditional funding and operational autonomy for black and minority-led organizations in response to the “urban crisis” of the 1960s. However, the program struggled to engage white Episcopalians in its sacramental vision and disregarded black Episcopalian voices, revealing its limitations and white establishment bias. While the GCSP showcased the potential for sacramental social action, it fell short due to constraints and failure to address the “urban crisis” as divine judgment on the very foundation of the church’s white establishment power. Instead, the program served as an incomplete penance, acknowledging the sacramental nature of the world and God’s reconciling grace, but ultimately inadequate as a sacramental response to colonial racial capitalism. Lacking the solidarity and critique required for efficacious sacramental action, the GCSP revealed the constraints of the white Episcopal Church to act sacramentally in a sacramental world.
The women and men that make peace: Introducing the Mediating Individuals (M-IND) dataset
Authors: Kreutz Joakim , Cárdenas Magda Lorena
Published: January 2024

This article presents new data on the individuals who mediate (M-IND) in all active UCDP dyads and lethal MIDs, 1989–2019. The dataset contributes to the systematic study of conflict management in several important respects: it covers both international and internal conflicts, it covers low-intensity violence, and it provides information on individual mediators, who appointed them, and type of mediation. Besides presenting the data collection and descriptive statistics, the article engages with the literatures on multiparty mediation and women, peace and security. M-IND shows that women more commonly are appointed as mediators by nongovernmental organizations than by states and international organizations. Our analysis suggests that greater equality in mediation efforts correlates with the use of more varied mediation strategies and is associated with a greater chance of reaching peace agreements.
Public opinion on trading with the enemy: Trade’s effects on the risk of war
Authors: Beesley Celeste , Oak Eliza Riley
Published: January 2024

While studies show that the public disapproves of trade with adversaries, political discourse has historically used security rhetoric to both justify and oppose trade with threatening states. Does emphasizing the potential of trade to exacerbate or mitigate security risks sway public opinion? Is public opinion malleable regardless of the level of threat? These questions become increasingly important as security and economic interactions between states become more intertwined. In a 2019 survey experiment, Ukrainian citizens report more optimism about the effects of trade with Russia (engaged in conflict with Ukraine since 2014) when told that trade decreases security risks. They are more pessimistic when presented with information that trade increases the risk of conflict. In contrast, attitudes about trade with a non-threatening trading partner (the European Union) are unaffected. This study demonstrates that the security effects of trade can both improve and worsen attitudes about trade with politically salient adversaries, even in the context of actual conflict. However, security rhetoric is unlikely to change public opinion about trade with non-threatening states unless they are viewed as reliable allies. Public opinion about trade, thus, responds to rhetoric about security, rather than representing an inflexible constraint on firms’ and states’ trade with adversaries.
‘Why do I have to learn this?’
Authors: Anderman Eric M. , Sheng Yue , Cha Wonjoon
Published: January 2024

Students’ valuing of academic content impacts their engagement in learning and plays a pivotal role in shaping their future academic and career choices. Fortunately, practicing educators can integrate many readily applicable strategies into teaching to enhance students’ valuing of academic content. Drawing from expectancy-value theory, Eric M. Anderman, Yue Sheng, and Wonjoon Cha present five evidence-based instructional strategies with concrete examples that aim to enhance students’ valuing of academic content. These strategies can be implemented with minimal additional work for teachers and at little or no additional financial cost to schools.
Key lessons from research about project-based teaching and learning
Authors: Saavedra Anna Rosevsky , Rapaport Amie
Published: January 2024

For many students, project-based learning (PBL) can be more engaging than more traditional instructional approaches. Over the past 15 years, Anna Saavedra and Amie Rapaport studied seven inquiry-based approaches. Their research shows that PBL has a positive effect on students’ achievement and development of important soft skills. Schools can maximize chances of success by providing expert-created, high-quality, adaptable materials; aligned professional learning opportunities; and a supportive schoolwide culture. Some of the challenges of PBL implementation include the tension between breadth and depth of content, keeping projects central to the curriculum, misalignment of standardized assessments with PBL, and financial requirements.
Motivating adolescents to read
Authors: Mac Iver Martha Abele , Davis Marcia H. , Mac Iver Douglas J.
Published: January 2024

Motivating today’s adolescents to read is a challenge. Martha Abele Mac Iver, Marcia H. Davis, and Douglas J. Mac Iver discuss the kinds of literacy instructional practices that address what we know about adolescent motivation. They also review several evidence-based literacy interventions designed to engage and motivate adolescent readers that can potentially lead to improvements in student reading motivation and academic outcomes.
A crisis of mattering: A conversation with Angela Maiers
Authors: Vail Kathleen
Published: January 2024

The lessons Angela Maiers has learned from her students prompted her to explore the importance of mattering. She discovered that being valued is not a socioemotional or mental health issue. It is rooted in biology. Maiers has written four books on the concept of mattering and unleashing individual genius in students, including Genius Matters and Classroom Habitudes. She spoke with Phi Delta Kappan about what schools get wrong about student motivation, how mattering interventions take little time but yield big results, and what gives her hope.
Engaging, motivating, and supporting students through feedback
Authors: Duckor Brent , Holmberg Carrie
Published: January 2024

Learning is iterative. It takes time and effort. Real progress in any subject requires we engage, motivate, and support learners as they take next steps to improve their work. Brent Duckor and Carrie Holmberg show how teachers can use progress guides as a formative feedback tool to re-engage and support students where they are, while keeping the focus on concrete steps they can take to move forward in the learning cycle. Drawing from research and case study evidence, they highlight how students and teachers can move conversations forward in safe and respectful ways. Without relying on graded judgments, the progress guide approach preserves the goals of continuous improvement and recenters learning for all students.
Backtalk: Teaching historical reasoning helps democracy thrive
Authors: Parker Walter C.
Published: January 2024

Beneath the turmoil over book bans, Advanced Placement courses, and teaching about race and slavery lurks a sobering fact about historical knowledge: History is not only about what happened in the past but also about how we know it. Understanding history means grasping both substance and method. If students are asked simply to memorize information about the past, rather than investigate it, then they have learned no way to distinguish historical claims from myths, legends, and lies. The work of history teachers is to build students’ historical reasoning skills so they can determine what is true.
The Impact of Illegitimate Tasks on Volunteer Participation: The Perspective of Psychological Capital
Authors: Miao Qing , He Yuhang , Zhu Xingkui
Published: January 2024

How do illegitimate tasks in volunteering affect volunteer participation? Previous research has focused only on the unidimensional effects of illegitimate tasks on volunteer participation. This study used the Job Demands-Resources model to investigate the multidimensional effects of illegitimate tasks on volunteer participation and the potential mechanisms of the effects. Based on three waves of survey data from 1768 Chinese volunteers, we found that illegitimate tasks negatively affect volunteer attitudes and volunteer outcomes by reducing volunteers’ psychological capital. This study develops a mediated model about the effects of illegitimate tasks on volunteer attitudes and outcomes. This study also makes related recommendations, such as asking volunteer organizations to offer stress-coping courses and encouraging volunteers to share their personal volunteering experiences.
Refugee Placemaking and Community in San Francisco: Building a Little Saigon Community in San Francisco, from the Tenderloin Neighborhood Development Corporation Archives (1980-2000)
Authors: Nguyen Minh Q.
Published: January 2024

The article draws from Tenderloin Neighborhood Development Corporation (TNDC) archival materials, housed in the San Francisco History Center, to present a case study of how post-1975 Vietnam War refugees (from Vietnam, Laos, and Cambodia) and a collection of actors collectively affected the local space (1980-2000). This article (1) examines the discourse of “neighborhood stabilization” amidst housing precarity, (2) discusses the implications of refugees as “revitalizers” and “entrepreneurs,” and (3) documents the role of community partnerships and urban planning in building a Little Saigon community in the heart of San Francisco. Overall, the article argues that efforts to build affordable housing within a unique urban planning environment were instrumental in the formation of the Little Saigon community of San Francisco, and it demonstrates how local affordable housing and the built environment in refugee resettlement sits at the nexus of competing discourses about development and about inclusion.
Nostalgia and Health: A Longitudinal Network Analysis of Different Nostalgic Experiences
Authors: Huang Kuan-Ju , Uricher Raphael
Published: January 2024

The study examines the long-term dynamics of the relationship between nostalgia and health using a population-based longitudinal sample in the Netherlands ( N = 958). We identified five types of nostalgia— Home, Peers and shared experiences, Emotional security, Innocence, and Leisure and media—and explored their relationships with health using network analyses. We found bidirectional relationships between nostalgia and health over a 1-year interval. Self-rated health and mental health negatively predicted nostalgia centered on Peers and shared experiences, Emotional security, and Innocence. Nostalgia, especially Emotional security and Innocence, negatively predicted self-rated health and mental health. The effects were further moderated by age. Cross-lagged relationships from nostalgia to health were found in younger but not older adults, while relationships from health to nostalgia were found primarily among older adults. In sum, we demonstrate the importance of considering age and type of nostalgia when exploring long-term relationships between nostalgia and health.
Children’s Opportunities and Constraints in European Parent Care Over Time: A Within-Family Approach
Authors: Vergauwen Jorik
Published: January 2024

The role of children's caregiving has received substantial attention in studies on care in old age. Previous research shows that children’s care provision is strongly intertwined with both their individual and siblings’ situation regarding employment and geographic parent-child distance. This study uses data from six waves of the Survey of Health, Ageing and Retirement in Europe (SHARE), taking a within-family approach, to examine how caregiving is (re-)distributed between siblings over time. The provision of continuous parent care is observed more frequent and volatile in European countries with a family-based care system. The results from family fixed-effects regression models demonstrate that children working less than siblings persist in caregiving more. Living closest to parents facilitates children to keep up care efforts, while changing to living closest enhances the start of parent care. This study suggests that geographic distance is vital in the long-term organization of parent care between siblings.
RESCUER: Combining Passive and Active Learning Techniques to Teach Food Sustainability
Authors: Banu Narmin Tartila , Darmody Aron , Neilson Leighann C.
Published: January 2024

This paper discusses the creation and implementation of an experiential learning assignment focused on the United Nation’s Sustainable Development Goal (SDG) 12, which aims to ensure sustainable consumption and production patterns. Using a grounded theory approach that combines analyzing 90 senior-level marketing students’ reflective essays alongside 63 pre- and post-assignment survey responses, we develop the “RESCUER” framework which combines active and passive learning elements. We demonstrate how active learning layered on top of passive methods can be an effective means to generate more responsible consumer behaviors within a complex food supply system. Students begin with passive learning components in the form of readings and lectures (labeled Resources), before Engaging with mindfulness in an active learning activity that involves the selection, purchase, and preparation of perishable food for a salad. The framework also includes the important effects of Social influence and its role in how Cognizance and Underlying problem salience are generated. Finally included are factors that Expedite the process of generating cognizance and problem salience such as the ready availability of relevant facilities (e.g., the existence of a garbage sorting system), which can enable more Responsible consumer behaviors.
Recommendations for supporting healthcare workers’ psychological well-being: Lessons learned during the COVID-19 pandemic
Authors: Korman Melissa B. , Di Prospero Lisa , DasGupta Tracey , Sinyor Mark , Anthony Samantha J. , Kastner Monika , Ellis Janet , Steinberg Rosalie , Maunder Robert
Published: January 2024

Healthcare workers are at risk of adverse mental health outcomes due to occupational stress. Many organizations introduced initiatives to proactively support staff’s psychological well-being in the face of the COVID-19 pandemic. One example is the STEADY wellness program, which was implemented in a large trauma centre in Toronto, Canada. Program implementors engaged teams in peer support sessions, psychoeducation workshops, critical incident stress debriefing, and community-building initiatives. As part of a project designed to illuminate the experiences of STEADY program implementors, this article describes recommendations for future hospital wellness programs. Participants described the importance of having the hospital and its leaders engage in supporting staff’s psychological well-being. They recommended ways of doing so (e.g., incorporating conversations about wellness in staff onboarding and routine meetings), along with ways to increase program uptake and sustainability (e.g., using technology to increase accessibility). Results may be useful in future efforts to bolster hospital wellness programming.
Comparative simulation of intraperitoneal aminoglycoside regimens for patients with peritonitis on automated peritoneal dialysis
Authors: Ariano Robert E , Zelenitsky Sheryl A , Davis Christine , Sathianathan Christie , Wolowich William R
Published: January 2024

Background:

Intraperitoneal (IP) aminoglycosides (AGs) continue to be the cornerstone of empiric management of peritonitis. AG dosing during automated peritoneal dialysis (APD), however, has not been well studied in patients with peritonitis. We sought to identify differences in AG exposure in the peritoneum and plasma for two different dosing regimens with little supporting evidence in patients on APD with peritonitis.

Methods:

A retrospective design that utilised the peritoneal and plasma concentration–time data from a prior study of 18 continuous ambulatory peritoneal dialysis (CAPD) patients with peritonitis to generate an in silico peritoneal and plasma PK model. This model was then used to compare via simulation using Phoenix© WinNonlin Software with IP AG dosing for a loading-dose regimen (1.5 mg/kg first dose) versus a fixed-dose regimen (0.6 mg/kg/d) in patients on APD with peritonitis.

Results:

Outcome measures were (1) percentage of time where peritoneal peak concentrations/minimal inhibitory concentration (MIC) ratio >10, (2) AUC/MIC > 74 and (3) plasma Cmin concentrations. Both regimens resulted in > 90% optimal peak/MIC ratio and AUC/MIC ratios on days 1 and 5 of the dose protocol. The loading-dose regimen resulted in IP exposures that were 2.5 times greater in the peritoneal compartment on day 1. By day 5, both protocols resulted in similar accumulation of AG plasma Cmin concentrations of 2.5–3.4 mg/L versus 2.4–3.3 mg/L, respectively, for the loading-dose regimen versus fixed-dose regimen.

Conclusions:

The current international guidelines for the treatment of peritoneal dialysis-associated peritonitis can continue to recommend the fixed-dose regimen for those on APD with the addition of plasma Cmin monitoring after 3 days to assess for drug accumulation.
Development of a landscape in NE Minnesota, from the Early Holocene to Forest-harvesting, Agriculture and Industry
Authors: Anderson R Scott , Dubois Nathalie , Brown Erik T , Stockhecke Mona , Johnson Ronald
Published: January 2024

An array of lake sediment proxies including paleobotanic, geochemical, and historical records has been used to determine former environments of Bugbee Pond, a small, mesotrophic pond in northeastern Minnesota. Much research has been produced on the history of climate and vegetation change of the region, yet we have little information on the impact of human settlement. This well-dated, high resolution, multi-proxy record is important for its length and concentration on the historic period. The lake itself became established by ~7000 years ago. Pollen evidence suggests a transition between the regional Prairie Period to the Great Lakes mixed conifer – hardwood forest was established in the region at this time. XRF data suggest dry basin accumulation early in the record after ~7000 cal yr BP, but lake levels substantially increased by ~5600 cal yr BP, during a regionwide climatic transition to more humid conditions. Birch and boreal conifers increased after about 3800 cal yr BP; further increases in boreal conifers occurred by ~2000 cal yr BP. Anthropogenic vegetation changes during the Historic period, beginning in the late 19th century, is well represented by forest clearance of white pine ( Pinus strobus), followed by increases in early successional species and an increased sediment accumulation rate due to land clearance. Establishment of farming communities locally are shown by occurrence of corn ( Zea mays) and oat ( Avena sativa) pollen, and pasturing and grazing are documented by Rumex, Fabaceae and Poaceae pollen, as well as coprophilous fungi, such as Sordaria. The increase and subsequent decline in Pb and S concentrations in the uppermost sediments are mirrored by historically documented, nearby industrial activities.
Are We Measuring ADHD or Anxiety? Examining the Factor Structure and Discriminant Validity of the Adult ADHD Self-Report Scale in an Adult Anxiety Disorder Population
Authors: Alarachi Arij , Merrifield Colleen , Rowa Karen , McCabe Randi E.
Published: January 2024

Adults with clinical anxiety have significant symptom overlap and above average rates of attention-deficit/hyperactivity disorder (ADHD). Despite this, ADHD remains a vastly under-detected disorder among this population, indicating the need for a screener with well-understood symptom dimensions and good discriminant validity. The current study compared competing models of ADHD as well as discriminant properties of self-reported ADHD symptoms as measured by the Adult ADHD Self-Report Scale (ASRS-v1.1) in 618 adults with clinical anxiety. A three-factor correlated model of Inattention, Impulsivity, and Hyperactivity, with the movement of one item, talks excessively, to a factor of Impulsivity from Hyperactivity fit better than the one-factor, two-factor, and traditional three-factor models of ADHD. Discriminant properties of the screener were fair to good against measures of clinical anxiety and distress; however, some items within the Hyperactivity factor (e.g., difficulty relaxing; feeling driven by a motor) loaded more strongly onto factors of clinical anxiety than ADHD when measures were pooled together. These results suggest that clinicians making differential diagnoses between adult ADHD and anxiety or related disorders should look for evidence of ADHD beyond the overlapping symptoms, particularly for those within the Hyperactivity factor.
Digital methods for sensory media research: Toolmaking as a critical technical practice
Authors: Chao Jason , van Geenen Daniela , Gerlitz Carolin , van der Vlist Fernando N
Published: January 2024

‘Digital methods’ turn to medium-specific and online avenues for social and cultural research. While these approaches foster empirical media studies, it has become increasingly challenging to ‘follow the medium’ and ‘repurpose’ its methods. The prominence of sensory media such as ‘smart’ networked devices (e.g. mobile phones) in mundane practices and their infrastructural dependencies confront media scholars with highly contingent objects of study. Yet, studying such sensor-based devices is crucial, for they enable continuous and unnoticed monitoring of everyday (inter)activity. The article suggests that developing digital methods for sensory media can be understood as specific ‘critical technical practice’ (CTP) by engaging with two toolmaking stories. It draws on and emphasises the fundamental similarity between CTP and digital methods which both aim at conjoining technical engagement and understanding with methodological reflection. The toolmaking stories explicate the making of and the limitations to developing digital methods for increasingly obfuscated mobile sensory media, exploring the possibilities of repurposing their functionality and data. They include building tools for app code analysis focused on apps’ capacity to track sensor data, as well as for ‘sensing’ and analysing network traffic of mobile devices in use. The featured toolmaking then unravels distinctive research affordances, that is, action possibilities for ‘static’ and ‘dynamic’ modes of analysis grappling with the technicity of mobile sensory media and their data. We argue that toolmaking as CTP for sensory media studies implies engaging with these media as entangled infrastructures, examining not just their social, but also their technical ‘multi-situatedness’. This involves investigating the ‘liveliness’ of their data, or how it is generated, processed and made sense of. In conclusion, we discuss implications for ‘doing digital methods’ in sensory media research. Toolmaking itself becomes an inevitable form of media research and critique, inviting and challenging researchers to deploy the media’s situatedness for their investigations.
Co-designing behavioural activation for depression for autistic adolescents: A case series
Authors: Mohamed Zameer , Russell Ailsa , Palmer Melanie , Simonoff Emily , Hollocks Matthew J
Published: January 2024

Autistic youth are at high risk of depression, but there are few psychological interventions that have been specifically designed for use with this population. Behavioural activation (BA) is a particularly promising approach for autistic adolescents, having an established evidence-base for the treatment of depression in non-autistic people, and with a strong focus on behavioural, rather than cognitive change, which is a challenge for some autistic people. In this study, we worked with autistic adolescents and clinicians to co-design a BA-informed intervention to be delivered in an online format. We then conducted a pilot case-series with seven autistic adolescents with depression. Our focus was on establishing the acceptability and feasibility of the intervention but clinical outcomes on both self- and parent-reported symptoms of depression and anxiety are also presented. Our results indicate the intervention to be acceptable and feasible for autistic adolescents, with six out of seven participants being retained to the end of the intervention. Qualitative feedback indicated that all participants found the intervention a positive experience and would recommend it to others. Similarly, all participants found the online format acceptable, with 64% preferring this format to face-to-face therapy. Qualitative feedback and suggestions for refinement will also be discussed.
Who will govern the metaverse? Examining governance initiatives for extended reality (XR) technologies
Authors: Egliston Ben , Carter Marcus , Clark Kate Euphemia
Published: January 2024

It is increasingly common to see policymakers, industry and regulators calling for governance of the ‘metaverse’ – often envisioned as a technological stack supported by extended reality (XR) technology. This article reports on a content analysis of calls to govern XR, published between March 2020 and May 2023 ( n = 181), aiming to understand who is calling for XR governance, what is being governed and why. Findings reveal that XR governance was advanced by government, civil society and industrial stakeholders, and was scoped around four major issues (‘privacy’, ‘safety, equity and inclusion’, ‘competition’, and ‘commercialisation’). Governance solutions to emerging XR technologies included a reliance on currently existing laws and regulations, and predominantly, a more anticipatory set of approaches (largely scoped around industrial self-governance, education and best practice) focusing on the media-specific harms and affordances of XR.
The societal context of professional practice: Examining the impact of politics and economics on journalistic role performance across 37 countries
Authors: Mellado Claudia , Hallin Daniel C. , Blanchett Nicole , Márquez-Ramírez Mireya , Jackson Daniel , Stępińska Agnieszka , Skjerdal Terje , Himma Marju , McIntyre Karen , Hagen Lutz M. , Amiel Pauline , Abuali Yasser , Fahmy Nagwa , Boudana Sandrine , Chen Yi-Ning Katherine , Davidov Sergey , De Maio Mariana , Frías Vázquez Maximiliano , Garcés Miguel , Humanes María Luisa , Herczeg Petra , Lee Misook , Lin Christi I-Hsuan , Melki Jad , Mick Jacques , Mincigrucci Roberto , Ninković Slavnić Danka , Nolan David , Olivera Dasniel , Olmedo Samantha , Pizarro Marcela , Quinn Fergal , Szabó Gabriella , Van Leuven Sarah , Viveros Aguilar Diana , Wyss Vinzenz
Published: January 2024

The impact of socio-political variables on journalism is an ongoing concern of comparative research on media systems and professional cultures. However, they have rarely been studied systematically across diverse cases, particularly outside Western democracies, and existing studies that compare western and non-western contexts have mainly focused on journalistic role conceptions rather than actual journalistic practice. Using journalistic role performance as a theoretical and methodological framework, this paper overcomes these shortcomings through a content analysis of 148,474 news stories from 365 print, online, TV, and radio outlets in 37 countries. We consider two fundamental system-level variables—liberal democracy and market orientation—testing a series of hypotheses concerning their influence on the interventionist, watchdog, loyal-facilitator, service, infotainment, and civic roles in the news globally. Findings confirm the widely asserted hypothesis that liberal democracy is associated with the performance of public-service oriented roles. Claims that market orientation reinforces critical and civic-oriented journalism show more mixed results and give some support to the argument that there are forms of “market authoritarianism” associated with loyalist journalism. The findings also show that the interventionist and infotainment roles are not significantly associated with the standard measures of political and economic structure, suggesting the need for more research on their varying forms across societies and the kinds of system-level factors that might explain them.