bluuebunny/crossref_metadata_2025 huggingface dataset:
A systematic review and meta-analysis of intraarterial chemotherapy for non muscle invasive bladder cancer: Promising alternative therapy in high tuberculosis burden countries
Authors: Rahman Zakaria Aulia , Hidayatullah Furqan , Lim Jasmine , Hakim Lukman
Published: February 2024

Introduction: Local therapies for high risk non-muscle-invasive bladder cancer (NMIBC) such as intravesical chemotherapy (IVC) have shown a high rate of progression and recurrence. Intravesical Bacillus Calmette-Guérin (BCG) for local therapies has been shown to reduce progression and recurrence in patient with NMIBC. However, its potential role is limited in high burden countries for tuberculosis (TB) due to its low specificity that can cause wrong diagnosis or false positive in patients with clinically diagnosed tuberculosis. BCG vaccine that has to be given for most people in tuberculosis endemic countries will induce trained immunity that could reduce the effectivity of intravesical BCG for NMIBC. Moreover, intravesical BCG is contraindicated in patient with or previous tuberculosis. The potential clinical benefit of intraarterial chemotherapy (IAC) in delaying the recurrence and progression of high-risk NMIBC have been investigated with promising results. We aimed to conduct a meta-analysis to evaluate the potential anti-tumor effect of IAC in NMIBC. Methods: We conducted a comprehensive search of published articles in Cochrane Library, Pubmed, and Science-Direct to identify relevant randomized controlled trials (RCTs) and observational studies comparing IAC alone or combined with IVC versus IVC/BCG alone in NMIBC. The protocol of preferred reporting items for systematic review and meta-analysis (PRISMA) was applied to this study. Results: Four RCTs and 4 cohort observational studies were eligible in this study and 5 studies were included in meta-analysis. The risk ratio of tumor recurrence was reduced by 35% (RR = 0.65; 95% CI 0.49-0.87; p = 0.004) in IAC plus IVC, while recurrence-free survival (RFS) was prolonged by 45% (HR: 0.55; 95% CI, 0.44-0.69; p < 0.001). The risk of tumor progression was reduced by 45% (RR = 0.55; 95% CI 0.41-0.75; p = 0.002) and tumor progression-free survival (PFS) was also prolonged by 53% (HR: 0.47; 95% CI, 0.34-0.65; p<0.001). Some RCT’s had high or unclear risk of bias, meanwhile 4 included cohort studies had overall low risk of bias, therefore the pooled results need to be interpreted cautiously. Subgroup analysis revealed that the heterogeneity outcome of tumour recurrence might be attributed to the difference in NMIBC stages and grades. Conclusions: The IAC alone or combined with IVC following bladder tumor resection may lower the risk of tumor recurrence and progression. These findings highlight the importance of further multi institutional randomized controlled trials with bigger sample size using a standardized IAC protocol to validate the current results.
Interdevice Agreement between a Smartphone and a Commercial Pupillometer
Authors: Rattan Yamini , Girgla Kawalinder Kaur , Mahajan Gaurav , Prasher Pawan
Published: February 2024

Background:

The reliability of dynamic pupillometry parameters varies from one pupillometer to another, making it difficult to standardize the values for any particular device. Hence, further studies are required to evaluate the agreement of various pupillometer devices and explore their utility in routine clinical settings.

Aim:

This study sought to evaluate the agreement between smartphone and commercial pupillometer measurements in routine clinical settings.

Methods:

The study included pupillary measurements obtained by a single investigator from 100 healthy participants (200 eyes) with each pupillometer. Pupillary measurements taken by a smartphone pupillometry application (reflex pupillary light reflex analyzer by Brightlamp [Indianapolis, IN, USA]) were compared with a commercial pupillometer (neurological pupil index-200, NeurOptics Inc., Irvine, USA).

Results:

The comparison of descriptive statistics revealed a statistically significant difference between the smartphone and commercial pupillometers for various parameters, including maximum diameter, minimum diameter, constriction velocity (CV), maximum CV, and dilatation velocity (P < 0.05), except for latency (P = 0.36). The intraclass correlation coefficient revealed poor agreement between the two devices (<0.50).

Conclusion:

The measurements by smartphone pupillometry application were found to be unreliable, indicating that they may not be an ideal substitute for commercial pupillometers in their present form in the Indian population. Further studies with larger sample size as well as improvements in the processing and interpretation of the measurements by the software, are needed to determine its utility in routine clinical settings.
Integrating yoga with education in the modern schooling system
Authors: Sinha Atul , Kumari Sony
Published: February 2024

The aim of this paper is to make a case for integrating yoga with education in the modern schooling system and to propose a theoretical model based on a synthesis of ancient knowledge and modern research. The paper is based on literature review of child and adolescent mental health, case for character education, case for school-based yoga intervention, ancient texts of yoga, and modern research on benefit outcomes of yoga. A comprehensive understanding of yogic principles from ancient texts and outcome benefits from modern research has gone into the development of a theoretical model of yoga in education. There is a large body of research evidence, suggesting that yoga in education can aid the development of physiological well-being, cognitive efficacy, emotional control, and desirable personality traits. Ancient literature on yoga provides its underlying principles, sequence of practices, and their interconnectedness. The theoretical model is based on the eight limbs of yoga derived from ancient literature. Modern research provides the evidence of benefits. The benefits show that yoga may aid in the development of the whole child, character building, social-emotional learning training, and developing the power of concentration. These findings make a compelling case for the inclusion of yoga in the school curricula. Most researches into school-based yoga have varying degrees of rigor in methodology and are based on short periods of interventions. If yoga in education is widely implemented, it will provide an opportunity for more methodologically rigorous research as well as longitudinal studies. This will help to both improve the school-based yoga programs and build more solid evidence of its efficacy. This paper is unique because it juxtaposes the process-based ancient knowledge and outcome-based modern research. This allows for a more comprehensive theoretical model of yoga in education.
An integrative approach (Vedic and Western) to Yoga Sādhanā in our times
Authors: Tilak Shrinivas
Published: February 2024

A survey of available literature on Yoga Sādhanā (philosophy and practice of yoga) in our times suggests that it has been built up using conceptual frameworks and categories developed in modern (mostly Western) intellectual tradition. Traditional advocates and practitioners of yoga on their part feel (justifiably so) that contemporary Yoga Sādhanā is a product of appropriation of whatever the moderns deemed useful in yoga after detaching it from its Vedic and Indic context while at the same time retaining exegetical control over its interpretation and dissemination. That human beings think, judge, feel, and act differently is incontestable. Such “differently” posited difference, however, cannot be total or exclusive. Because otherwise, no difference could be identified, articulated, and claimed. This suggests the existence of a deeper similarity that makes understanding and communication among cultures and philosophies possible. In light of the preceding, it is argued here that Yoga Sādhanā, and the metaphysics undergirding it, should be approached in a collaborative, i.e., modern Western (“Etic” or outsider) as well as traditional Vedic (”Emic” or insider) scholarly perspectives. Such an integrative framework accordingly is proposed here incorporating (by way of illustration) insights discernible in the works of two Western (Ian Whicher and Soraya Franco) and two Vedic (Swami Kuvalayananda and T. Krishnamacharya) advocates of Yoga Sādhanā.
Efficacy of X-Ray Phytosanitary Irradiation on the Infectivity and Reproduction of Angiostrongylus cantonensis in Experimentally Infected Rats
Authors: Jarvi Susan I. , Kaluna Lisa M. , Hess Steven C. , Hamilton Lindsey , Antaky Carmen , Sugihara Robert T. , Leinbach Israel L. , Tagami Yaeko , Steel Argon , Howe Kathleen , Jacquier Steven , Cookman Forrest , Diaz Jocelyn , Jacob John , Follett Peter
Published: February 2024

Angiostrongylus cantonensis is a globally distributed nematode and the leading cause of eosinophilic meningitis in humans. As a global hotspot for this disease, Hawaii’s agricultural exports may be contributing to the spread of A. cantonensis. Phytosanitary irradiation doses of 150 or 400 Gy provide quarantine security against multiple insect pests. We evaluated the in vitro and in vivo effects of phytosanitary irradiation on infectious, third-stage, A. cantonensis larvae. In vitro experiments directly exposed larvae to irradiation doses ranging from 200 to 1,000 Gy. Results showed low mortality and no dose response across all treatments 27 days post-irradiation. In vivo studies isolated larvae from wild-caught Parmarion martensi after exposure to x-ray irradiation at doses of 0, 150, and 400 Gy and infected them into laboratory rats. Fourteen rats were assigned to each treatment and infected with 50 larvae from their assigned irradiation dose. Results at 3 and 6 weeks post-infection demonstrated a significant negative dose response in regard to the number of larvae that migrated to the brain and adults found in the pulmonary artery. No irradiated larvae that grew into adults were able to produce eggs. These findings indicate that x-ray irradiation does not result in the direct mortality of A. cantonensis larvae; however, it does affect the infectivity and reproduction of A. cantonensis within its definitive host, the rat. Phytosanitary irradiation at doses ≥150 Gy appears to be an effective means of preventing the establishment of viable populations of A. cantonensis, thus reducing the potential for global spread due to agricultural exports from Hawaii.
9100品質マネジメントシステムにおけるAQAP 2110の適用に関するガイダンス
Authors:   IAQG-1 Standards Committee
Published: February 2024

この文書は、供給者が9100の規定を遵守する場合の、AQAP-2110の適用に関する情報及びガイダンスを提供するために作成され、発行された。この文書は、AQAP-2110-SRD.2及びIA9137として発行されている。この文書は、NATO及び業界によるAQAP-2110及び9100の関係の理解及び利用を容易にするために、NATO及び業界の代表者が協同で策定した。AQAPは、調達国が対外有償軍事援助（FMS）を調達手段として利用する場合に、必要となる場合がある。

この文書の目的は、調達者及びその9100供給者によるAQAP-2110要求事項の解釈の共通化に寄与することである。

この文書の内容は法的位置づけも契約上の位置づけも有せず、AQAP-2110の要求事項又は9100の要求事項のいずれに対しても取って代わるものでも、追加するものでも、削除するものでもない。

様々な状況が、作業、工程の種類、又は使用される機器、及び関わる要員のスキルのような要因に左右されて存在し得るため、このガイダンスは網羅的なものと見なされることも、また、契約書の要求事項を満たすための特定の手段や方法を義務付けるものと見なされることも望ましくない。ステークホルダーは、これらの要求事項を満たすために、他の手段や方法が使用され得ることを認識すべきである。

このガイダンスの利用者は、AQAP 2110要求事項が、契約書に引用されているとおり、供給者や二次供給者に義務付けられていることに留意することが望ましい。
在 9100 质量管理体系内 应用 AQAP 2110 的指南
Authors:   IAQG-1 Standards Committee
Published: February 2024

编制和发布本文件旨在供应商遵守 9100 规定的情况下，就 AQAP-2110 的应用提供相关信息和指南。本文件的发布号为 AQAP-2110-SRD.2 和 IA9137。本文件由 NATO 和行业代表联合编制，供 NATO 和行业内使用，旨在促进 AQAP-2110 和 9100 的使用及对其之间关系的理解。当采购国使用对外军售 (FMS) 作为其采购方式时，可能需要 AQAP。

本文件旨在促进采购方及其 9100 供应商对 AQAP-2110 要求解释的通用性。

本文件内容不具有法律或合同地位，亦不会取代、增加或取消 AQAP-2110 或 9100 的任何要求。

由于可能存在多种条件（取决于工作或过程类型、所用设备和所涉人员的技能等因素），不应将本指南视为包含所有事宜，亦不应将本指南视为强加满足合同要求的具体手段或方法。相关方应意识到，可使用其他手段或方法来满足这些要求。

本指南使用者应谨记，当合同引用了 AQAP 2110，其要求对于供应商和次级供应商具有强制性。
СОВЕТСКАЯ НАЦИОНАЛЬНАЯ И ТЕРРИТОРИАЛЬНАЯ ПОЛИТИКА НА ПРИМЕРЕ ИЗМЕНЕНИЯ ГРАНИЦ БЕЛОРУССИИ В 1926 ГОДУ
Authors:   Prima- kov National Research Institute of World Economy and International Relaions, Moscow, Russia, Гронский Александр
Published: February 2024

В статье исследуется советская национально- территориальная политиканапримерепередачи территорий из одной союзной республики в другую. В 1926 г. власти советской Белоруссии потребовали передать территорию Гомельского и Речицкого уездов, которые были частью Гомельской области РСФСР. Население Гомельского и Речицкого уездов массово не желало, чтобы их территория была передана в Белоруссию. Но советская власть полностью проигнорировала желание народа. Гомельский и Речицкий уезды были отделены от РСФСР и переданы в БССР.
Patients' satisfaction with the quality of care upon implementation of electronic health records system at the 37 Military Hospital, Ghana.
Authors: ADOMAH-AFARI Augustine , ANAKWA-AWUKU Adelaide , GADEKA Dominic
Published: February 2024

Background: To resolve delays faced by patients when accessing health services, the electronic health records system (EHRs) was introduced as part of the health management information system (HMIS) to enhance the quality of care.
Objective: This study assessed patients' satisfaction with the quality of care upon the implementation of the electronic health records system at the 37 Military Hospital in Ghana.
Methods: The study adopted a cross-sectional study design using a quantitative method. A simple random sampling method was applied to recruit 228 outpatients who were seeking healthcare at the time of data collection to respond to a structured questionnaire. A Chi-square test and logistic regression analysis were used to assess the association between the dependent variable and independent variables. A p-value of 0.05 at a 95% confidence interval was used as the threshold for statistical significance.
Results: The results showed a high quality of care with respect to attention to patients' needs (M=3.68, SD=0.525), the responsiveness of health providers to emergencies (M=3.81, SD=0.651), the efficiency of services rendered (M=3.78, SD=0.576), timeliness of healthcare (M=3.78, SD=0.576), patient-provider communication (M=3.42, SD=0.683) and general patients' care (M=3.86, SD=0.528). Similarly, the results showed high patient satisfaction in relation to waiting time for services (M=4.32, SD=0.93), adequacy of attention from health providers (M=3.29, SD=0.98), health provider-patient relationship (M=3.63, SD=1.05) and level of service provision after the implementation of EHRs (M=3.89, SD=0.95). Efficiency of services rendered (OR=0.36, 95% CI; 0.276, 0.653, p < 0.05), timeliness of healthcare (OR=0.42, 95% CI; 0.153, 0.693, p < 0.05),and general patients' care (OR=0.43, 95% CI; 0.023, 0.678, p < 0.05) were strong predictors of patients' satisfaction.
Conclusion: The study demonstrated patients' overall satisfaction with the operation of electronic health records systems. The study recommends that the management of the 37 Military Hospital should continuously improve the quality of care of the health services to ensure sustained patient satisfaction
Functional status and quality of life of women with infertility in Southern Ghana: A cross-sectional study
Authors: Oppong Stella Sarpomaa , Naab Florence , Akuffo Richard Adjei , Donkor Ernestina Safoa
Published: February 2024

Background: The desire to have children seems more intense in cultures that perceive childbearing as the primary reason for marriage. In such cultures, infertility reduces the functional status of women.

Objective: This study investigated the relationship between functional status and quality of life of women with infertility in selected fertility centres in Ghana.

Methods: A total of 167 women were recruited from four infertility treatment hospitals in Southern Ghana. Two standardised questionnaires were used: Functional Status and the Fertility Quality of Life questionnaire (FertiQol). A cross-sectional design was used to examine the relationship between functional status and fertility-related quality of life (FertiQol). Pearson product-moment correlation and multilinear regression analysis were performed using the Statistical Package for Social Science (SPSS) version 20.0.

Results: The result of the Pearson product-moment correlation showed a statistically significant strong positive correlation between mental health and core areas (emotional, mind/body, relational and social) of fertility-related QoL (r=0.616, p<0.001). The regression analysis indicated the demographic characteristics and functional status of the women collectively explained approximately 44% of the variance in the women's Core FertiQoL (R2 = 0.437, F (12, 125) = 8.081, p < 0.001). Individual evaluation of the predictors showed that mental health (p <0.001) and quality of social interaction (p= 0.005) statistically significantly contributed to the functional status of the women.

Conclusion: The findings suggest that to improve the quality of life (QoL)of women's infertility, their quality of social interaction, mental health, and work performance should be considered in their treatment and general care.
Urethral calculus causing retention of urine in a female
Authors: Kyei Yamoah Kwame Mathew Kyei
Published: February 2024

Urethral calculi (stones) have been noted to be extremely rare in females due to their short urethra that has a straight course. And for such a calculus (stone) to cause retention of urine is extremely rare. Its management is to retrieve the calculus if it is small as to traverse the external Urethral meatus. This is best avoided if the calculus is large , in such a situation the calculus is manipulated back into the bladder and fragmented. The image of a urethra calculus impacted in the urethra of a female and causing retention of urine is presented in this clinical image with the intended course of management stated.
PELATIHAN PENGINPUTAN DATA SECARA OTOMATIS DI MICROSOFT EXCEL MENGGUNAKAN DATA FORM DAN MACRO VBA (BASIC FOR APLICATION) DI SMA IT UNGGUL AL-MUNADI MEDAN
Authors:   Universitas Potensi Utama, Siregar Elida Tuti , Alfina Ommi , Puspita Dahlia , Safii M. ,   STIKOM Tunas Bangsa
Published: February 2024

Automatic data input using Microsoft Excel as a number processor or application for automatically processing data such as numerical values, mathematical formulas and making financial reports hone students' skills in knowledge of the use of computer technology, which is a basic need nowadays to operate a computer, a skill that students must master in the future world of work. because computer operating skills are really needed by companies, especially the Microsoft Excel application to process technology-based company data in determining decision makers in a company. This training will produce graduates who can operate computers and input data automatically. This activity provides skills and knowledge to students at SMA IT Unggul Al Munadi Medan using Microsoft Excel to process and input data automatically with Visual Basic forms and macros (VBA).
PENGENALAN DAN PELATIHAN SOFTWARE PENGOLAHAN DATA SPSS DAN SMARTPLS DI UNIVERSITAS MIKROSKIL
Authors:   Universitas Mikroskil, Perangin-Angin Naca , Lubis Tya Wildana Hapsari
Published: February 2024

One of the popular tools for data processing is the Statistical Package for the Social Sciences (SPSS) and Structural Equation Modeling (SEM) with SmartPLS. Understanding data processing has a very important role in preparing the final assignment. Data processing is a critical step in scientific research methodology. Students who compose their final assignment need to know and understand the techniques, stages and interpretation of results correctly so that their research has a strong basis. So the aim of Community Service Activities is to provide knowledge and understanding to final semester students who have started preparing their final assignments at Mikroskil University. Provide practical understanding and skills to students in using SPSS and SmartPLS as data processing tools. This training was carried out directly using SPSS and SMArtPLS software. Based on the results of the answers to the pre-test and post-test questions of the training participants, it can be seen that there is an increase in understanding in the introduction and use of SPSS and SmartPLS software before and after, for details, see Figure 7 for a comparison of the pre-test and post-test results. So it can be concluded that the introduction and training of SPSS and SmartPLS data processing software at Mikroskil University was successful.
Properti Syariah Perspektif Konsep Pemasaran dan Etika Bisnis Islam
Authors: Soumena Fadly Yashari , Sulastri Endang
Published: February 2024

Penelitian ini bertujuan untuk menganalisis Pengaruh Lead Generation dan Etika Bisnis Islam terhadap Kinerja Karyawan di Properti Syariah Haluoleo Land Kota Makassar. Waktu penelitian dilakukan pada bulan Juni 2023 sampai dengan bulan Juli 2023. Jenis penelitian kuantitatif dengan menggunakan pendekatan survei. Sumber data yang digunakan adalah data primer, populasi yang digunakan sebanyak 60 karyawan properti syariah haluoleo land kota Makassar. Sampel yang digunakan sebanyak 60 sampel dengan menggunakan teknik sampel jenuh. Metode analisis data menggunakan analisis regresi linear ber-ganda dan teknik analisis data menggunakan aplikasi SPSS versi 26. Hasil penelitian ini menunjukkan bahwa (1) secara parsial lead generation berpengaruh positif dan signifikan terhadap kinerja karyawan di properti sya-riah haluoleo land kota Makassar, (2) secara parsial etika bisnis Islam ber-pengaruh positif dan signifikan terhadap kinerja karyawan di properti syariah haluoleo land kota Makassar, (3) secara simultan lead generation dan etika bisnis Islam berpengaruh positif dan signifikan terhadap kinerja karyawan di properti syariah haluoleo land kota Makassar. Berdasarkan hasil penelitian di atas, im-plikasi pada penelitian ini menunjukkan variabel lead generation dan etika bisnis Islam berpengaruh terhadap kinerja karyawan karena memberikan dampak yang baik terhadap peningkatan kinerja dari setiap karyawan di properti syariah haluoleo land kota Makassar.
 
This research aims to analyze the influence of lead generation and Islamic business ethics on employee performance at Haluoleo Land Syariah Properties, Makassar City. The time of the research was carried out from June 2023 to July 2023. This type of quantitative research used a survey approach. The data source used is primary data, the population used was 60 employees of Haluoleo Land sharia property Makassar city. The samples used were 60 samples using saturated sampling techniques. The data analysis method uses multiple linear regression analysis and the data analysis technique uses the SPSS version 26 application. The results of this research show that (1) partially lead generation has a positive and significant influence on employee performance at the Haluoleo Land sharia property in Makassar City, (2) partially Islamic business ethics has a positive and significant influence on employee performance at the Haluoleo Land sharia property in Makassar City. Makassar, (3) simultaneously lead generation and Islamic business ethics have a positive and significant effect on employee performance at the Haluoleo Land sharia property, Makassar city. Based on the research results above, the implications of this research show that the lead generation variables and Islamic business ethics influence employee performance because they have a good impact on increasing the performance of each employee at the Haluoleo Land sharia property, Makassar city
Financial literacy and Performance of Women-Owned SMEs in Garissa County, Kenya
Authors:   Department of Accounting and Finance, School of Business and Economics, Moi University. PO box 103991 – 00101 Nairobi, Kenya, Mukoswa Odunga, Robert
Published: February 2024

The SME sector is crucial for Kenya's government, driving inclusive economic growth, regional development, employment, and poverty reduction. Women-owned SMEs face challenges, including limited risk tolerance, hindering expansion. Financial skills, operating costs, and other issues contribute to their struggles. This paper explored the impact of financial literacy on the financial performance of women-owned SMEs in Garissa County, Kenya. The study focused on budgetary proficiency and debt navigation skills. Using a descriptive survey design and anchored on the Dual Process Theory, the research involved 399 sampled women owned SMEs out of a population of 763. The findings revealed significant relationships between budgetary proficiency and financial performance (Pearson’s r= 0.690, p<0.000) and debt navigation skills and financial performance (Pearson’s r=0.515, p<0.000). These predictors explain approximately 26.5% of the variance in women-owned SME performance (R Square = 0.265). The regression coefficients indicate that budgetary proficiency has a minimal effect (β = 0.010, p=0.027<0.05), influencing performance by 1.0%, while debt navigation skills have a moderate effect (β = 0.351, p=0.000<0.05), influencing performance by 35.1%. The study recommends strengthening financial management training, customizing financial literacy programs to address diverse gaps, and promoting inclusive budgeting practices among women-owned SMEs. Enhancing debt navigation skills is particularly emphasized for a more positive impact on the financial performance of women-owned SMEs in Garissa County.
Assessment of Financial Information Quality: Evidence from Tunisian Context
Authors:   Faculty of Economic sciences and Management of Tunis, University of Tunis El Manar, El Manar II- B.P. 94- Romena- 1068, Tunisia, ALOUI Sameh , BELANES Amel ,   College of Business, University of Jeddah, Saudi Arabia, Lab GEF2A, High Institute of Management of Tunis, University of Tunis, Tunisia
Published: February 2024

The present paper aims at assessing the financial information quality within Tunisian firms. We analyzed a sample annual data of 78 financial and non-financial Tunisian listed companies. We use the level of discretionary accruals and if the firm restate its financial statement or not as proxies of financial information quality. Our main results show that the financial information quality is globally low. We note a high level of discretionary accruals within financial firms compared to non-financial pears. We also find that financial firms are less likely to restate their financial statements compared to those of non-financial firms.
Understanding Factors That Affect Social Media Advertisement Adoption for Small Medium Enterprises in Indonesia the Case of Facebook Advertisement
Authors:   School of Business Management, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, Indonesia, Irawan Aldo Jay
Published: February 2024

Advancement of technology in the field of marketing has been one significant factor in assisting Small Medium Enterprises (SMEs) to increase their competitiveness. Meta, as a technological company, provide Facebook advertisement as a mean of digital social media advertising. One of the challenges that Meta faced is to attract more Facebook ads adoption especially in the Small Medium Enterprise sector. This research objective is to understand the factors that affect social media advertisement adoption, in this case Facebook advertisement, for small medium enterprises in Indonesia. There are eight variables that are believed to influence customer intention to adopt Facebook advertisement which are performance expectancy, effort expectancy, social influence, facilitating condition, hedonic motivation, price value, perceived technology security and self-efficacy. The main data was collected by an online survey and 350 SMEs participated in it. The respondents are SMEs that operate in Indonesia and either have not use Facebook advertisement service or do not use the service anymore. The sample was gathered using non-probability convenience sampling and the data was analysed using structural equation model technique. The research found that Self-efficacy is the highest influencing variable that are statistically significant to influence SMEs intention to adopt Facebook advertisement. Effort expectancy and social influence are found to be statistically significant to influence SMEs intention to adopt Facebook advertisement. Hedonic motivation and price value factor are found to be statistically significant to influence intention to adopt Facebook ads for SMEs that have use the service but choose not to use it anymore. In the contrary, the factor of performance expectancy, facilitating condition and perceived technology security are found to be not statistically significant to influence intention to adopt Facebook ads among Indonesia SMEs. The research suggests Meta to prioritize an effort to increase SMEs self-efficacy in using Facebook advertisement by giving free training and certification. Other suggestions are to partner with relevant key opinion leaders (KOL)/communities, creating engagement with SMEs through events and giving monetary incentives such as discount coupons. For future research, researcher suggest different/smaller respondent demography and/or different social media advertising platform. Research with respondent that are actively using Facebook advertising service could also give additional insight to the study.
Clinical Features: Diverticular Disease is on the Rise
Authors:   Médico General, Residente de Medicina Familiar, Departamento de Clínicas Médicas- Pontificia Universidad Javeriana de Cali, Colombia, Medina Dra. Maira Alejandra Guayambuco , Imbachi Dra. Leidy Diana Imbachi ,   Médico General. Universidad Santiago de Cali. Departamento de Urgencias, Hospital San Juan de DIOS, Cali- Colombia., Torres Dr. Jhan Sebastian Saavedra ,   Médico General, M.Sc en Cuidados paliativos- Universidad de Nebrija (Madrid- España). Residente de Medicina Familiar – Departamento de Clínicas Médicas- Pontificia Universidad Javeriana de Cali, Colombia., Ortega Dr. Marco Antonio Medina ,   Universidad del Cauca - Colombia. Profesor de la cátedra cuidados generales y Gastrointestinales en el paciente pos operatorio.
Published: February 2024

Diverticulosis refers to the presence of diverticula, or herniations of the intestinal mucosa and submucosa, most often in the sigmoid colon. More than one half of patients over age 50 have incidental colonic diverticula. Diverticulitis is the most common complication of diverticulosis, occurring in up to 20% of patients, and results from a microperforation of a diverticulum from inspissated fecal material that often becomes a phlegmon, or a pericolic or intra - abdominal abscess. The presented clinical case is about diverticular disease (Diverticulosis). It generally affects older patients. It is produced by herniation of the mucosa and submucosa through the muscular layer of the colon.
The Relationship between Empowerment and Income Level in Rural Families inSerang Regency and Pandeglang Regency, Banten Province
Authors:   Department of Economic, M.Pd Prof. Dr. Sudadio,
Published: February 2024

A family is said to be prosperous if it can meet its basic needs, namely food, clothing, housing, health and education. Indicators of family empowerment can be measured through household income derived from work activities. The purpose of this study was to determine the relationship between the level of empowerment and the amount of income in rural families in Serang and Pandeglang districts. The quantitative research approach was used to obtain data from respondents using survey instruments on the level of empowerment and income level. The data analysis used is correlation analysis with the statistical formula produchmoment pearson. Based on the data obtained, there is a strong correlation of 0.795 between the level of family empowerment and the level of family income.
Failures in Fixed Dental Prostheses: A Clinical Survey on Causes and Longevity
Authors:   Associate Professor, Faculty of Dentistry, Galala University, Attaka, Egypt, Fouad Maha , Allam Eman ,   Researcher, Oral and Dental Research Institute, National Research Centre, Cairo, Egypt
Published: February 2024

Crown and bridge failures are considered one of the most frequent challenges that dentists deal with on a daily basis. The aim of the current study was to assess the causes of failures in fixed dental prostheses in patients reporting to the dental clinics at Ahram Canadian University, Cairo, Egypt. Using a comprehensive clinical survey, causes of failures and serviceability patterns of the fixed dental prostheses (FDP) were explored in a sample of 80 patients (mean age 39.7±11) visiting the clinic for complications related to FDP. Patients were clinically and radiographically examined, and all symptoms related to their complaints were recorded. Descriptive analysis was performed, and SPSS version 22 was used for statistics. Results indicated that most of the failures were mechanical in nature (30%), followed by biological failures (20%), and then aesthetics reasons (11%). 45.7 % of the FDP served for 1-5 years, 28.6 % served for 6-12 months, 14.30% served for more than 5 years, while the least numbers of prostheses (11.4%) served for less than 6 months. Proper patient selection, diagnosis, and treatment planning is essential to maintain and increase the longevity of FDP. It is also crucial to educate patients about good dental hygiene and prosthesis maintenance as well as for the dentist to fully recognize the disadvantages of each dental material to prevent the problems they induce and be able to make the best decision.
Scalar Electromagnetic Energy, Making STAR TREK Physics Real
Authors:   William S Alek, CEO, Intalek Research, Sarasota, FL 34231-4807, USA., S Alek William
Published: February 2024

Back in 1997, I first heard about energy researcher, Tom Bearden on the Art Bell show, “Coast to Coast AM.” Tom spoke about Free Energy and Anti-gravity. He also spoke about an upcoming conference featuring him lecturing about this incredible topic. What is Free Energy and Anti-gravity I thought? Everyone heard of or perhaps seen a UFO flying about in our skies above? But how does this amazing technology work? So, without question, I had to go to this conference. I booked a flight, made my hotel and car reservations and off I went on this grand adventure not knowing where this was going to lead? Art Bell frequently mentioned on his late-night radio show, “You want to take a ride?”
Could cigarette smoke be associated with metaplastic type of meibomian gland dysfunction?
Authors: Ali Ebtahaile , Sheikh Naukhaiz Taqi
Published: February 2024

Madam,
The meibomian glands are located in the tarsal plates of the eyelids. The diseases involving these glands belong to a broad classification. However, the metaplastic diseases of the meibomian gland are the focus of this letter.1 We intend to propose the possible role of cigarette smoke as an active agent in developing metaplastic type of meibomian gland dysfunction (MGD).
A meibomian gland is made up of multiple acini that are arranged around a long central duct. Owing to its vigorous function of producing meibum and maintaining tear film stability, the gland requires a constant turnover and differentiation of cells. Consequently, during this intricate cascade of continuous production and differentiation of cells, even a slight deviation from normality can lead to drastic pathological effects.2 We presume that oxidative stress can produce such a pathologic deviation.
One of the most common causes of increased oxidative stress in cells is exposure to cigarette smoke. It has also been experimentally established that cigarette smoke is a well-known inducer of metaplastic changes; especially known to cause squamous metaplasia in the bronchial epithelium.3 Therefore, exposure to cigarette smoke may also be a culprit when the meibomian orifice, owing to its superficial location on the eyelid, is exposed to the components of cigarette smoke. Cigarette smoke contains carbon particles and other toxic compounds that begin the cascade of inflammation and during the attempts of phagocytic elimination of these toxic compounds, inflammatory damage to DNA and proteins can occur.4 The aspect of protein damage and hyperkeratinization in response to increased oxidative stress has already been studied and implicated in the pathogenesis of MGD.2 Furthermore, it has been demonstrated that EGF (Epidermal Growth Factor) is produced in epithelial cells in response to smoke and that further increases the possibility of metaplastic as well as hyperplastic changes.5
Therefore, we suggest that there exists a strong relation between exposure to cigarette smoke and the development of metaplastic meibomian gland dysfunction. Further studies in this regard might help in prevention, as well as newer diagnostic approaches towards MGD especially in populations exposed to cigarette smoke on a regular basis.
Keberkesanan Penggunaan Aplikasi Pembelajaran Interaktif dalam Meningkatkan Motivasi serta Pencapaian Pelajar dalam Mata Pelajaran Fizik
Authors: Ajang Esther Emma , Mohammad Yasin Ruhizan
Published: February 2024

Penggunaan teknologi dalam pendidikan terutamanya aplikasi pembelajaran interaktif adalah signifikan dalam membantu meningkatkan motivasi belajar dan pemahaman pelajar dalam konsep sains yang abstrak. Dalam usaha membangunkan bakat masa depan seperti yang dinyatakan dalam Rancangan Malaysia Ke-12 dan selaras dengan Pelan Pembangunan Pendidikan Malaysia 2013 – 2025, kerajaan telah berusaha menyediakan infrastruktur seperti elektrik dan capaian internet kepada semua sekolah. Kesedaran guru terhadap kelebihan dan kepentingan pengajaran dan pembelajaran menggunakan teknologi dan aplikasi yang berkualiti adalah amat penting. Oleh itu, kajian ini bertujuan untuk mengkaji keberkesanan aplikasi pembelajaran interaktif terhadap peningkatan pencapaian pelajar dalam mata pelajaran Fizik. Seramai 50 orang pelajar Tingkatan 4 dan Tingkatan 5 daripada dua buah sekolah di Daerah Serian, Sarawak telah dipilih secara sampel bertujuan untuk menyertai kajian. Kajian ini adalah berbentuk kuantitatif. Pengumpulan data adalah melalui penggunaan ujian pra, ujian pasca dan borang kaji selidik atas talian menggunakan aplikasi Google Form. Data dianalisis secara deskriptif dan inferensi menggunakan perisian SPSS versi 26.0. Dapatan kajian pertama menunjukkan bahawa terdapat perbezaan yang signifikan di antara markah ujian pra dan ujian pasca (min=30.80, s.p.=4.247); (t = 51.275, p =.000). Dapatan kajian kedua menunjukkan bahawa terdapat hubungan yang signifikan di antara motivasi belajar Fizik setelah menggunakan aplikasi pembelajaran interaktif dengan peningkatan pencapaian pelajar dalam mata pelajaran Fizik (r = 0.747, n = 50, p < 0.05). Oleh itu, guru hendaklah menambahbaikkan kepakaran dalam penggunaan teknologi pendidikan serta merancang dan melaksana aktiviti pengajaran dan pembelajaran yang lebih bermakna. Kajian masa depan dapat diperluaskan kepada faktor jantina dan kepada populasi yang lebih luas.
THE EUROPEAN CONVENTION FOR THE PROTECTION OF HUMAN RIGHTS AND FUNDAMENTAL FREEDOMS IN THE RUSSIAN LEGAL SYSTEM: REASONS FOR DENUNCIATION
Authors: Vyskrebtsev Bogdan S. , Ryabokonev Sergey I. , Sergeev Andrey B.
Published: February 2024

It is indicated that, having joined the Council of Europe, Russia consistently implemented the European Convention into the Russian legal system. However, on 02/23/2023 Russia denounced the Convention for the Protection of Human Rights and Fundamental Freedoms of November 4, 1950. The article solves the problem of identifying and analyzing the reasons for the adoption of such a decision by the state.
Methodology. A system-structural approach is used in the analysis of the activities of the ECHR for the consideration of complaints and the resolution of cases. In this approach, the axio-teleological method is applied — the analysis of problems through the prism of constitutional values. The author argues and scientifically substantiates the conclusion that the evolutionary and universal types of interpretation of the norms of the Convention, combined with the desire of the Council of Europe to reduce the time historical framework required for the formation of a single European worldview and values among the peoples that are not peculiar to the mentality of Russian citizens,
has caused Russia’s differentiated approach to the implementation of the ECHR decisions. The opinion is expressed that Russia’s voluntary withdrawal from the Council of Europe is necessarily forced. The further development of the objective process of states’ striving for peace, the rule of law, and the provision of natural rights and freedoms in the historical perspective will exclude from the list of natural rights and freedoms at the present stage the individual results of socio-cultural globalization that are mistakenly perceived as “values”. The opinion is expressed that it is inappropriate to denounce all the provisions of the Convention on the Protection of Human Rights and Fundamental Freedoms. By leaving the previously ratified provisions of section 1 “Rights and Freedoms” in force, Russia will thus confirm its commitment to true European values without infringing on mentality and sovereignty; it will demonstrate its independence from the opportunistic decisions of states currently in difficult economic and political situations.
TACTICS OF OVERCOMING COUNTERACTION TO THE INVESTIGATION OF OCCUPYING THE HIGHEST POSITION IN THE CRIMINAL HIERARCHY
Authors: Kondratyuk Sergey V.
Published: February 2024

The issues of tactics of overcoming counteraction to the investigation of the occupation of the highest position in the criminal hierarchy are considered. Based on the generalization of investigative and judicial practice, typical ways of countering the investigation of this crime are identified. The article defines that for the purpose of such counteraction, interested persons use message encryption, as well as falsification, destruction, modification of material objects and documents. Witnesses are forced to refuse to testify. In general, such methods are reduced to masking information about the
functions performed by the suspect and about other signs of his status position in the criminal hierarchy. Organizational and administrative, regulatory, judicial, punitive functions are masked by friendly advice, rules of the hostel, criticism of violators, resolution of domestic conflicts, etc. The disposal of the thieves’ cash register is disguised as the organization of the mutual assistance cash register. The status signs of this crime are expressed in the occupation of the highest position in the criminal hierarchy, according to the traditions and rules of the criminal subculture. It is shown that a typical way of distorting status signs is to represent a thieves’ ritual as a playful form of behavior. Tactical techniques that contribute to obtaining reliable data on the signs of a suspect occupying a higher position in the criminal hierarchy are aimed at verifying the reliability of sources of evidentiary information. The article suggests effective tactical operations, such as the appointment of forensic examinations, interrogation, and other investigative actions, in combination with operational search
measures of a search and verification nature.
TO THE QUESTION OF THE HISTORY OF THE DEVELOPMENT OF INTERNATIONAL LEGAL REGULATION TO COUNTER THE THREAT OF THE SPREAD OF INFECTIOUS DISEASES
Authors: Alimov Alimirze A.
Published: February 2024

The article brought to the attention of the reader examines the history of the adoption and subsequent formation of a system of global international legal acts that ensured the formation of a modern international legal framework for the mechanism of countering, both by individual states and the world community as a whole, the spread of infectious diseases dangerous to life and health. Special attention is paid to a number of international legal acts in this area that have their effect at the level of any geographical region of the globe. The analysis of the international legal documents cited in the article allows us to formulate a number of conclusions showing the stages of evolution of
the international legal regulation of combating the spread of infectious diseases: from the priority of the purely national economic interests of states to the declaration and consolidation in international documents of the legal obligations of states to ensure social equality in the implementation of the right to health. A significant stage in this evolution was the consequences of the Second World War and the tragic experience of totalitarian regimes that contributed to a qualitative leap in the development of the institution of human rights. In particular, in shaping the perception of the international obligations of states to counteract the spread of dangerous infectious diseases as
a form of realization of the right to health. In conclusion, the author substantiates the need for the formation, as a natural continuation, of a new legal thinking aimed at perceiving the right to health as a global right “without state borders”.
ADMINISTRATIVE OFFENSE: SOCIALLY DANGEROUS OR SOCIALLY HARMFUL ACT?
Authors: Zakharchuk Sergey D. , Matveeva Yelena V.
Published: February 2024

The scientific article discusses issues related to the determination of the grounds for
the occurrence of administrative responsibility as one of the types of legal liability. The authors investigate scientific positions regarding the signs of an administrative offense. In general, agreeing with the opinion of scientists regarding the signs of an administrative offense, the authors of the scientific article are critical of the identification of such a sign of an administrative offense as “public danger”. The paper analyzes the scientific literature, law enforcement practice and documents of state authorities, from which it follows that questions about the differentiation of “public harmfulness” or “public danger” of administrative offenses have not been resolved to date. Examining the materials of judicial practice, as well as decisions of higher courts, scientific positions of scientists, the authors come to the conclusion that administrative offenses are “socially harmful” acts. Otherwise, there would be no boundaries and differences between a crime and an administrative offense. The article also formulates the author’s concept of an administrative offense.
OKHRANALOGY — A NEW SCIENCE OF PROFESSIONAL SECURITY ACTIVITY: THE FIRST ACQUAINTANCE
Authors: Shestakov Valery I.
Published: February 2024

The article substantiates the expediency of forming a new branch of science — 
okhranalogy, the object of knowledge of which is professional security activity, which is a single, integral phenomenon that unites various types of protection. Based on the analysis of Russian and international sources, modern scientific theories, it is proved that professional security activity is a kind of legal activity, one of the legitimate means of ensuring national security. The system of the science of security is given, its essence and content are revealed, the object and subject, scientific and practical significance are determined.
PROCEDURAL ORDER: THE PROBLEM OF UNDERSTANDING
Authors: Zashlyapin Leonid A.
Published: February 2024

In the theory of criminal procedure, the concept of “procedural order” is not defined. The traditional object of research is the separate procedures for the production of procedural actions, the adoption of procedural decisions, fragments of criminal procedural activity. The understanding of the procedural order as a generic concept in relation to specific concepts (the order of inspection, the procedure for conducting a preliminary hearing, others) is not considered in science. The concept of “procedural order” is specific in relation to the concept of “legal order”. To reveal the features of the concept of “procedural order”, an analogy from the theory of I. Prigogine and I. Stengers about the emergence of order from chaos can be used. At the same time, the specific differences of the procedural order are its reliance on the dynamic characteristics of the branch of
criminal proceedings, the spatial and temporal structure, the elements of which are interconnected.