bluuebunny/crossref_metadata_2025 huggingface dataset:
Increasing Effectiveness of Genetically Modifying Mosquito Populations: Risk Assessment of Releasing Blood-Fed Females
Authors: Xia Siyang , Ury Jonah , Powell Jeffrey R.
Published: March 2021

Releasing mosquito refractory to pathogens has been proposed as a means of controlling mosquito-borne diseases. A recent modeling study demonstrated that instead of the conventional male-only releases, adding blood-fed females to the release population could significantly increase the program’s efficiency, hastening the decrease in disease transmission competence of the target mosquito population and reducing the duration and costs of the release program. However, releasing female mosquitoes presents a short-term risk of increased disease transmission. To quantify this risk, we constructed a Ross–MacDonald model and an individual-based stochastic model to estimate the increase in disease transmission contributed by the released blood-fed females, using the mosquito Aedes aegypti and the dengue virus as a model system. Under baseline parameter values informed by empirical data, our stochastic models predicted a 1.1–5.5% increase in dengue transmission during the initial release, depending on the resistance level of released mosquitoes and release size. The basic reproductive number (R0) increased by 0.45–3.62%. The stochastic simulations were then extended to 10 releases to evaluate the long-term effect. The overall reduction of disease transmission was much greater than the number of potential infections directly contributed by the released females. Releasing blood-fed females with males could also outperform conventional male-only releases when the release strain is sufficiently resistant, and the release size is relatively small. Overall, these results suggested that the long-term benefit of releasing blood-fed females often outweighs the short-term risk.
Atovaquone/Proguanil Resistance in an Imported Malaria Case in Chile
Authors: Chenet Stella M. , Oyarce Alan , Fernandez Jorge , Tapia-Limonchi Rafael , Weitzel Thomas , Tejedo Juan R. , Udhayakumar Venkatachalam , Jercic María Isabel , Lucchi Naomi W.
Published: March 2021

In November 2018, we diagnosed a cluster of falciparum malaria cases in three Chilean travelers returning from Nigeria. Two patients were treated with sequential intravenous artesunate plus oral atovaquone/proguanil (AP) and one with oral AP. The third patient, a 23-year-old man, presented with fever on day 29 after oral AP treatment and was diagnosed with recrudescent falciparum malaria. The patient was then treated with oral mefloquine, followed by clinical recovery and resolution of parasitemia. Analysis of day 0 and follow-up blood samples, collected on days 9, 29, 34, 64, and 83, revealed that parasitemia had initially decreased but then increased on day 29. Sequencing confirmed Tyr268Cys mutation in the cytochrome b gene, associated with atovaquone resistance, in isolates collected on days 29 and 34 and P. falciparum dihydrofolate reductase mutation Asn51Ile, associated with proguanil resistance in all successfully sequenced samples. Molecular characterization of imported malaria contributes to clinical management in non-endemic countries, helps ascertain the appropriateness of antimalarial treatment policies, and contributes to the reporting of drug resistance patterns from endemic regions.
Comparison of Anti-Dengue and Anti-Zika IgG on a Plasmonic Gold Platform with Neutralization Testing
Authors: Rojas Alejandra , Natrajan Muktha S. , Weber Jenna , Cardozo Fátima , Cantero César , Ananta Jeyarama S. , Kost Jessica , Tang Meijie , López Sanny , Bernal Cynthia , Guillén Yvalena , Mendoza Laura , Páez Malvina , Pinsky Benjamin A. , Waggoner Jesse J.
Published: March 2021

Antibody cross-reactivity confounds testing for dengue virus (DENV) and Zika virus (ZIKV). We evaluated anti-DENV and anti-ZIKV IgG detection using a multiplex serological platform (the pGOLD assay, Nirmidas, Palo Alto, CA) in patients from the Asunción metropolitan area in Paraguay, which experiences annual DENV outbreaks but has reported few autochthonous ZIKV infections. Acute-phase sera were tested from 77 patients who presented with a suspected arboviral illness from January to May 2018. Samples were tested for DENV and ZIKV RNA by real-time reverse transcription-PCR, and for DENV nonstructural protein 1 with a lateral-flow immunochromatographic test. Forty-one patients (51.2%) had acute dengue; no acute ZIKV infections were detected. Sixty-five patients (84.4%) had anti–DENV-neutralizing antibodies by focus reduction neutralization testing (FRNT50). Qualitative detection with the pGOLD assay demonstrated good agreement with FRNT50 (kappa = 0.74), and quantitative results were highly correlated between methods (P < 0.001). Only three patients had anti–ZIKV-neutralizing antibodies at titers of 1:55–1:80, and all three had corresponding DENV-neutralizing titers > 1:4,000. Hospitalized dengue cases had significantly higher anti-DENV IgG levels (P < 0.001). Anti-DENV IgG results from the pGOLD assay correlate well with FRNT, and quantitative results may inform patient risk stratification.
The Problem of Destiny in Akan and Yoruba Traditional Thoughts: A Comparative Analysis of the Works of Wiredu, Gyekye and Gbadegesin
Authors: H. Majeed M.
Published: March 2021

Many African scholars have expressed varied thoughts about the concept of a person, specifically about that which constitutes a person in African philosophy. These philosophers include Kwasi Wiredu, Kwame Gyekye and Segun Gbadegesin. What they have in common, though, is that their ideas on the concept of a person issue largely from the traditional philosophies of some West African peoples. Wiredu and Gyekye reflect on Akan conceptions while Gbadegesin carries out his discussions from the Yoruba cultural perspective. This paper examines the thoughts of these prominent philosophers, with a particular focus on the constitution of the person and the nature of his or her destiny.
Rape and Adultery in Ancient Greek and Yoruba Societies
Authors: Olasope Olakunbi O
Published: March 2021

In Athens and other ancient cultures, a woman, whatever her status and whatever her age or social class, was, in law, a perpetual minor. Throughout her life, she was in the legal control of a guardian who represented her in law. Rape, as unlawful carnal knowledge of a woman, warranted a capital charge in the Graeco-Roman world. It still carries a capital charge in some societies and is considered a felony in others. As for adultery, it may be prosecuted in some cultures while in others it is a matter to be decided by the family council.This paper examines laws concerning the abuse of and exploitation of women in ancient and modern societies, especially within the context of their biologically determined roles and sexual culture. It also seeks to establish the socio-legal rights (if any) of women, especially those who were traumatised and sexually abused. The research method is mainly content analysis. It employs sources such as legal evidence in the form of recorded speeches of the Attic orators along with literary accounts, historical or legendary and epigraphic inscriptions.
Benchmarking, Standard Setting and Energy Conservation of Olefin Plants in Iran
Authors: Gowharifar S. , Sepehrian B. , Nasiri G. , Khoshgard A. , Momenifar M.
Published: March 2021

Olefin plants are one of the most energy intensive petrochemical plants in the world [1, 2]. In Iran more than 15% of petrochemical products are olefins and it will increase rapidly during next future, so improvement of energy efficiency in olefin plants is key element in NPC (Iranian National Petrochemical Company) plan for cost reduction and sustainable development. In this paper the energy consumption of existing olefin plants are compared with design condition and also world best technology. This comparison indicates the meaningful gap between operational and best condition. In this study the opportunities of energy saving in olefin plants are investigated using process integration tools and benchmarking. The result of this study indicates there is potential for energy consumption reduction up to 25% in Iranian olefin plants.
Numerical Investigation of Thermal Stability of Catalyst Granules with Internal Heat Generation in a Random Temperature Field
Authors: Derevich Igor , Galdina Daria
Published: March 2021

Method for numerical simulation of temperature of granules with internal heat release in a medium with random temperature fluctuations it is proposed. The method utilized solution of a system of ordinary stochastic differential equations describing temperature fluctuations of surrounding and granules. Autocorrelation function of temperature fluctuations has a finite decay time. The suggested method is verified by the comparison with exact analytical results. Random temperature behavior of a granule with internal heat release qualitatively differs from the results obtained in the deterministic approach. Mean first passage time of granules temperature intersects critical temperature is estimated at different regime parameters.
Hybrid Energy Harvester for Medical Sensor Node toward Real-Time Healthcare Monitoring
Authors: Mohsen Saeed
Published: March 2021

In healthcare applications, the remote monitoring for moving patients depends on medical sensor nodes, which should be mobile. Thus, the power mains of medical sensor nodes should be disconnected most of the time to monitor natural movements of patients. In this paper, a self-sustainable medical sensor node is proposed for healthcare monitoring applications. The node implementation consists of a microcontroller unit (MCU), a photo-plethysmography (PPG) sensor, a Bluetooth low energy (BLE) module, and a MPU module that includes a gyroscope with accelerometer. The power supply of the node is a hybrid energy harvester developed to provide a sustainable energy for the sensor node. The harvester is composed of a photovoltaic (PV) panel, a thermoelectric generator (TEG) module, a DC-DC converter, and a super-capacitor. Experimental results illustrate that the proposed node can monitor a physiological data on a mobile device using the BLE Terminal application.
Electronic information and education environment as a basis for ensuring education in pandemic settings
Authors: Sirina N. F. , Panova N. S. , Volynskaya A. V.
Published: March 2021

In order to ensure safe conditions for the education and upbringing of students, guided by the orders of the Ministry of Education and Science of Russia and Roszheldor from March 17, 2020, the implementation of all educational programs of higher, secondary professional education, additional educational programs (programs for advanced training, professional retraining, etc.) implemented in the university complex, including the completion of intermediate and state final certificates by students, as well as the completion of educational, industrial (including pre-diploma) practices for relevant educational programs are provided using remote technologies — in the Blackboard electronic information and educational environment, which is one of the elements of digitalization of the university complex. To optimize the educational process, the university developed a set of measures to improve and systematize work in an electronic information and educational environment, one of which was the transition from a traditional paper student’s record-book to an electronic one that functionally fully corresponds to a paper analogue. The purpose of introducing an electronic student’s record-book is to improve the quality of the provision of educational services through the integration and automation of individual information on the results of training in electronic form. The results of the development of educational programs by students in the electronic information and educational environment are automatically displayed in the electronic student’s record-book, which is especially relevant in pandemic conditions. The entire university complex is ready to continue the implementation of all educational programs of both of higher, secondary professional education, in full exclusively in remote mode using the electronic information and educational environment of Blackboard University.
Developing a unified centralized transport flow control system
Authors: Bagutdinov R. A. , Bezhuashvili D. V.
Published: March 2021

Currently, there is an increase in information for data mining in transport systems, the main reason is the increase in the number of heterogeneous sources. The relevance of the topic lies in the need to collect, process, aggregate, and model large volumes of unstructured information that cannot be effectively processed by traditional methods. With the increasing flow of vehicles, its diversity, there is a need to optimize the processes of transportation and logistics, increase the system safety of road traffic. The creation of an information knowledge base will help to solve a number of important problems, including: the efficiency of road use, reduction of toxic emissions, control and unloading of traffic flows, reduction in the number of accidents, and prompt notification of services.

The idea of developing a unified centralized traffic control system is described. To collect, store and process heterogeneous information, it is proposed to use a cloud infrastructure with split computation. For the purpose of high-quality processing and aggregation of heterogeneous information, it is recommended to investigate hidden dependencies in the data, build and analyze various aggregation options and interpret them in relation to specific tasks.

The system should connect all participants in ground traffic, collect dissimilar materials that can be obtained from their devices and a variety of sensors, and also automate the management and decision-making in transport systems. Unstructured information must be correctly interpreted, categorized, and consistently labeled to identify implicit relationships between data.

The scientific novelty of the research consists in the formation of the functions of the system being developed, the description of the main aspects, requirements, interfaces, models and methods for aggregating heterogeneous data.

The results of the work can be used not only for analyzing big data in the field of transport, but also in other directions when solving problems of processing heterogeneous information.
Finding Empathy in Historical Inquiry and Data Management Through an Educational Research Example
Authors: Chang Bo
Published: March 2021

In historical inquiry, researchers identify the research questions, specify the domain which relates to the research questions, and familiarize themselves with how the documents are structured and managed in the host library. In collecting data, researchers don’t need to constrain themselves with how documents are labeled by the archivists. They can break the boundaries of the labeled documents and find out how seemingly unrelated documents are actually inter-related. In analyzing data, positivists and constructionists view history differently, which results in different approaches to how historical data can be analyzed. Positivists believe in transparency and universal truths across the historical data through data generalization and inference. In addition to generalization and inference, researchers should situate themselves in the historical context, establish empathy to feel the historical moments, and interpret data in the historical context. Revisiting and evaluating the process of a historical inquiry allows researchers to find out the patterns of historical events and the important points that might be missing in the field. This also provides a chance for researchers to evaluate the hosting, storage and management of historical data and identify the ways which can help improve data management so that future researchers can easily access the data.
Introduction: Qualitative Analysis: Quantifying Quality and Qualifying Quantity
Authors: Moreira António , Costa António
Published: March 2021

As part of a partnership between The Qualitative Report (TQR) and Comissão Organizadora/Comité Organizador do CIAIQ2015 e do 6ºSIMEDUC (http://www.ciaiq.org), António Moreira and António Pedro Costa had edited a selection of papers from the conference to create a special issue for TQR.
Asking Questions in the Qualitative Research Context
Authors: Neri de Souza Francislê , Neri Dayse , Costa António
Published: March 2021

Research is based on a constant questioning process. All researchers should ask questions in every research phase, what is read, the research design definition, data analysed and the way they are discussed and how their conclusions are drawn. It is generally accepted that to start scientific research, irrespectively of the area of expertise, the starting point is the drafting of one or more research questions, ordinarily known as a research problem. However, for many, starting with a research programme, the idea of formulating one is always a challenge. Some do not know where to start and question whether the question is well formulated. Given these issues, this paper aims to clarify and reinforce the importance of formulating the research problem and/or question, where to get inspiration for its compilation, what are the steps to be followed for its refinement and what is its usefulness during the research process. We also intend to recommend the use of some software packages that may assist the researcher, during questioning in other research phases, and thus maintain internal coherence throughout the research, as well as obtain an answer to the research question.
Career Morph: Quantitizing Adversity in Academic Medicine
Authors: Isaac Carol , McSorley Rebecca , Schultz Alexandra
Published: March 2021

Many qualitative researchers reject textual conversion based on philosophical grounds although others believe it facilitates pattern recognition and meaning extraction. This article examined interview data from 52 physicians from a large academic medical center regarding work–life balance. Analysis ranked men and women in four career tracks: Clinician-Educator, Clinician-Researcher, Clinician-Practitioner, and residents. The purpose of this paper is to illustrate how a qualitatively driven (QUAL→quan) mixed method design illustrated differences between stratified groups. Although many initial codes were similar for men and women, their language was gendered and generational in context of work-life balance. Results indicated that women (and low-status men) expressed fewer strategies to successfully negotiate academic medicine. Quantitizing enhanced the interpretive description of adversity.
A Framework for Using Qualitative Comparative Analysis for the Review of the Literature
Authors: Onwuegbuzie Anthony , Weinbaum Rebecca
Published: March 2021

Onwuegbuzie, Leech, and Collins (2012) demonstrated how the following 5 qualitative data analysis approaches can be used to analyze and to synthesize information extracted from a literature review: constant comparison analysis, domain analysis, taxonomic analysis, componential analysis, and theme analysis. In a similar vein, Onwuegbuzie and Frels (2014) outlined how discourse analysis can be used. Thus, the purpose of this article is to provide a framework for using another qualitative data analysis technique to analyze and to interpret literature review sources—a process that we call a Qualitative Comparative Analysis-Based Research Synthesis (QCARS). Using a real review of the literature, we illustrate how to conduct a QCARS using a qualitative comparative analysis software program.
The Confessions of a Goat: An Oral History on the Resistances of an Indigenous Community
Authors: Jayaprakash Prabhakar
Published: March 2021

Betta Kurumba is an indigenous (also known as Adivasi / tribal) community living in the Gudalur block of Nilgiris district, Tamil Nadu, India. This district is part of the Western Ghats mountain range that runs parallel to the Western Coast of India. It is an anthropological research on a hamlet, Koodamoola, located inside a tea and coffee plantation, the Golden Cloud Estate (pseudonym). Few years ago, the owner (under legal contestation) of this plantation attempted to enforce a ban on rearing of livestock arbitrarily. Betta Kurumbas did not agree to this enforcement since they are the ancient inhabitants of this forest (now, plantations) and they resisted. Ethnography, oral history, and in-depth interviews are the methods used to understand their everyday resistances. The field intricacies such as powerlessness, atrocities and litigations forced me to narrate their resistances through the voice of a goat (a metaphor) and I have incorporated both factual and fictional elements. I neither attempting here to exaggerate nor demean the community by this way of narration. In broader context, I have written this story from a postmodern perspective. This paper brings forth multiple facets of their realities, power nexus between capitalists and apparatuses of the State, differences between and within the indigenous communities, and resistances as negotiations.
Language Teachers’ Evaluation of Curriculum Change: A Qualitative Study
Authors: Ostovar-Namaghi Seyyed
Published: March 2021

This study aims at theorizing language teachers’ evaluation of a top-down curriculum change by eliciting their perspectives through open-ended qualitative interviews. In line with grounded theory procedures, concepts and categories were theoretically sampled from the perspective of participants who were willing to share their views with the researcher. Iterative data collection and analysis revealed a set of categories which show the conflict of interest between practitioners and policy-makers. Practitioners focus on immediate classroom concerns and reject the syllabus change because of its lack of small-scale try-outs, inappropriate timing, vague methodology, inappropriate in-service program, learner homogeneity fallacy, unrealistic expectations and increased absenteeism among learners. On the other hand, focusing on issues beyond immediate classroom, policy makers advocate it since it is conducive to uniformity, convergent practice, efficiency and covert privatization. This conceptualization of teachers’ perspectives on curriculum change has clear implications for policy makers and teachers in this context and other similar contexts.
Empowering Belizean Youth through Photovoice
Authors: Chase Daniel
Published: March 2021

Today's youth are faced with a number of different "roadblocks" on their way to becoming successful adults. Navigating adolescence is often difficult in its own right, but many youths have to deal with issues such as, poverty, unsafe neighborhoods and schools, drug/alcohol addiction, and disjointed homes to name a few. Although not all youth are faced with the same obstacles, these abovementioned obstacles can detract youth from becoming socially productive. Using Photovoice, a process by which participants identify, represent and enhance their community using a specific photographic technique, this study connected Belizean youth to their community through the process of identifying and taking photos of community strengths and weaknesses. After completing shared data analysis, the photos and a description of the meanings behind the photos were presented to a number of dignitaries in the community. The main themes presented were Responsibility and Support. This presentation gave youths voice in their community and allowed them to discuss strategies on how to increase community strengths as a way to reduce community weaknesses. Upon completion of the presentation, the dignitaries answered questions posed by the youth and offered collaborative strategies on how to promote social change.
Developing Morally Sensitive Policy in the NICU: Donation after Circulatory Determination of Death
Authors: van Manen Michael , Kain Nicole
Published: March 2021

Policy development is an important activity for the practice of healthcare. Policies, after all, may cultivate common practices and ensure that best available evidence is employed in clinical decision making. Qualitative research and individuals with expertise in qualitative research methods have much to offer policy makers. We were confronted with the situation of developing policy for donation after circulatory death (DCD) for our newborn intensive care program. Due the moral-ethical complexities surrounding DCD, and the limited experience with DCD in this context, we approached policy development from an iterative design perspective employing qualitative methods. We describe our experience in employing this approach and the methodological implications of design as a method for policy development.
Construct Shift of Pre-Service Language Teachers on Globalized English within a Turkish Context
Authors: Özkan Yonca
Published: March 2021

The leading position of English as a global language has indisputably continued for several decades. This pivotal role has inevitably been influencing English language teaching and teacher education. The number of nonnative English speaking teachers has by far surpassed that of native English speaking teachers. This reality has led us to conduct this particular descriptive study involving Turkish senior pre-service language teachers acting as participants in a training as part of a course (Globalization in ELT), in which we investigated the participants’ perceptions towards globalized English regarding common themes in the journal and interview data. The findings revealed that although the majority of participants supported superiority of nativeness and inner circle culture prior to delivery of the course, following the training, their perceptions regarding pre- and post-training constructs displayed a rather different picture. The study has implications for teacher education involving material developers, curriculum designers, instructors, and students.
Life Plan Development in Young Adult Women: An Exploration Using Grounded Theory
Authors: Zambrano-Varghese Christina
Published: March 2021

Although research exists that explores career planning, romantic relationships, and decision making in women, it is not yet known how women understand and develop the goals that they hope to achieve throughout their lives. The current study aims to answer how women understand and go through the process of developing the life plans that they hope to pursue after college graduation. This research question was answered with Charmaz’s (2006) model of grounded theory by conducting 13 interviews with young adult women approaching college graduation, followed by one focus group which was used to validate emergent themes. It was found that life plan development is a longitudinal process that begins in childhood, but becomes more focused during college, with the help of mentors, tangible learning opportunities, and the growth that exists from experiencing hardship. These young adult women were able to identify important factors throughout the entire lifespan that had helped them hone in on their dreams, identifying positive and negative experiences they had had, particularly in regards to their gender development, which had helped motivate them to work towards their ultimate goals for their lives.
DISPARAGEMENT AS A PROCESSSING STIMULUS FOR HUMOR IN ADVERTISING
Authors: Hameed Irfan
Published: March 2021

Purpose - This research paper explores the mediating role of attitude towards the advertisement and attitude towards the brand in the relationships between disparagement as a processing stimulus for humor in advertising and purchase intention of the customer. Design/Methodology/Approach - Data has been collected from 202 individuals. Confirmatory factor analysis, structural equation modeling, moderation and mediation analysis have been applied and a good fit between the data and tested model was observed. As predicted, purchase intention was positively related with disparagement and full mediation effect has been found. The results of moderation analysis are quite interesting and have been presented with the help of a chart showing interaction effect. Findings - Findings provide media agencies with an insight into the audience emotional consequences in exposure to disparagement used in advertisements. Findings are particularly salient for national and multinational media agencies in Pakistan as well in the other parts of the world. Originality/Value - This is one of the first studies to provide empirical support for the relationships between disparagement and purchase intention in Western and non-Western (Pakistani) context.
FACTORS AFFECTING TRANSFER OF TRAINING AT WORKPLACE: STUDY OF SSGC, HYDERABAD
Authors:   Mehran University Institute of Science, Technology and Development (MUISTD), MUET, Jamshoro., Qureshi Qurat-ul-Ain
Published: March 2021

Purpose The reforms is the financial sector have resulted in numerical changes in the banking sector. In order to improve the financial health of the banks various norms have been introduced at regular intervals. As the banking sector constitutes a major component of the financial service sector the soundness of the banking sector is necessary for a dynamic and healthy economy. The establishment of a productive efficient and stable economy is possible only when a country is having a sound healthy banking sector. The study has been an attempt to analyse the comparative performance of selected public and public and private sector banks in India during the period 2003-2013 On the basis of their direct and indirect contributions to the society for socio- economy growth and its impact on quality of assets or NPA level of the banks Sampling Methodology For this purpose five leading Indian Banks from each of the Public and Private sector bank have been taken into consideration Findings of the study indicate that the performance of the private sectors bank is better from bankers view point but from the social view points public sector banks are better performers.
IMPACT OF SOCIAL MARKETING ON CUSTOMER PURSCHASE INTENTION
Authors:   Institute of Business & Technology, Karachi., Chanido Zafarullah
Published: March 2021

Purpose- This paper aims to show the effects of organizational climate, including perceived organizational support and supervisory support on employees’ service quality in the context of Foreign Tobacco Company of Bangladesh. Methodology/Sampling- A total of 175 questionnaires were distributed among the respondents using non-probability, convenience sampling technique. Out of these, only 120 questionnaires were found suitable for data treatment. The data was treated with the help of software SPSS 20, applying correlation and linear regression analysis tools for testing the hypotheses. Findings- The study established that there was a positive relationship of employee service quality with independent variables i.e. perceived organizational support, supervisory support and organizational climate. It also explained the extent to which the employees perceived their service quality in context of organizational climate and also the support they got from the firm. The study also identified some important areas that need further improvement in the service quality of employees. Practical Implications- Findings of the study clearly indicate that in order to get better service from the employees, Foreign Tobacco Company needs to be more considerate by focusing on employees’ problems, needs and accordingly provide them adequate support to mitigate their problems. The results also indicate that service quality of the employees is highly influenced by the organizational climate, supervisory support and organizational support. The managers at various tiers may seek help from the findings and render maximum possible support to the employees to enhance their commitment and loyalty.
HSCT FOR NON-HODGKIN LYMPHOMA
Authors: Baldissera Renata , Hallack Neto Abrahão Elias , Castro Renato , Perrini Guilherme , Silva Leandro De Pádua , Chiattone Carlos
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
GUIDELINES ON CELL THERAPY
Authors: Kondo Andrea , Ribeiro Andreza , Duarte Fernando , Silla Lucia , Kerbauy Lucila , Salvino Marco , Hamerschlak Nelson , Rocha Vanderson , Funke Vaneuza
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
OCULAR GRAFT-VERSUS-HOST DISEASE
Authors: Prieto Bárbara Leite de Souza , Rocha Eduardo Melani , Trindade Marilia , Serapicos Patrícia , Souza Rodrigo Guimarães de
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
THE USE OF COMPREHENSIVE GERIATRIC ASSESSMENT: A TOOL FOR DONOR SELECTION
Authors: Rodrigues Morgani , Duarte Fernando Barroso , Hamerschlak Nelson
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
Pembelajaran Outdoor Activity Melalui Deklarasi Anti Hoaks Pada Peserta Didik Sekolah Dasar
Authors: Firmansyah Obim , Okta Mulia Martika , Dias Mumpuni Sesya
Published: March 2021

Hoaks merupakan fenomena yang menarik untuk dikaji karena dapat merusak mental generasi muda, terutama bagi mereka yang tidak mampu menganalisis kebenaran berita hoaks itu. Tujuan penelitian ini adalah menganalisis peranan outdoor activity dalam menyiapkan peserta didik yang cerdas dan kompeten sehingga mampu membedakan antara informasi yang benar dan yang hoaks. Aktivitas masyarakat Desa Kepunduhan, Kecamatan Kramat, Kabupaten Tegal dapat dimanfaatkan sebagai tempat pembelajaran outdoor activity. Penelitian dilaksanakan melalui survey tentang aktivitas dan perilaku masyarakat sebagai tempat pembelajaran. Hasil penelitian menunjukkan bahwa bahwa pembelajaran outdoor activity melalui deklarasi anti hoaks, efektif sebesar 86% dalam memberikan pengaruh kepada peserta didik untuk memerangi berita hoaks. Sebanyak 55% responden memang masih mendengarkan berita yang banyak diperbincangkan, tetapi memilih untuk menganalisanya terlebih dahulu sebelum membicarakannya lagi pada orang lain. Sementara itu, sebanyak 40% peserta didik masih menggunakan smartphone untuk bermain sosial media dan membaca banyak berita didalamnya.
Identification of Managerial Competency Knowledge of Management Students at Jenderal Achmad Yani University
Authors: Mulyana Aam Rachmat , Khaerul Rizal Abdurahman
Published: March 2021

The development of increasingly sophisticated technology is driving the era of industrial revolution 4.0, impacting Indonesian millennials entering the era of the digital economy, artificial intelligence, big data, robotics, and so on, or known as disruptive innovation phenomenon. The development of entry-level managers shows that in 2011, the company's demand was smaller than the availability of first-level managers. While it is estimated that in 2020, the company's demand will be greater than the availability of first-tier managers. This causes Indonesia to experience a gap between the needs and availability of managers both in quality and quantity of 40 to 60 percent. This study emphasized on the identification of general managerial competency knowledge, competencies seen from the frequency of managerial competency knowledge use Managerial competency identification is carried out using semi-open questionnaires, in the form of assessment of 14 manager competencies contained in generic competency model of managers from Spencer & Spencer (1993) as a reference list of competency assessment. This study used a sample of some students who were in the 7th semester as many as 192 students. The results of this study showed the highest order of Knowledge Managerial Competency occupied by Analytical Thinking (Impact and Influence) while the lowest order occupied by Developing Other (Developing others), as well as low knowledge of competency impact influence, initiative, and information seeking in students of study programs majoring in management.
Collaborative Governance as a Strategy for Optimizing the Potential of Coastal Areas and Local Tourism: A Study in Tangerang Regency
Authors:   Department of Public Administration, Tadulako University, Palu, Indonesia, Tawil Muzakir
Published: March 2021

This research aims to study collaborative governance strategy in order to solve gap problem between abundance of natural resources but not equal in local management and constrained social phenomenon. Some barriers like low capacity that happen in street level government and local population. It will be interesting because paradox occure in abundance of advantages and welfare opportunity but cannot make local society out of local downturn and poverty (vicious circle). This research background is slum area phenomenon, low arrangement of local infrastructure, and poverty around tourism object and then attempted to explain stakeholder role in order to solve the probem. The research held in Banten Provine, especially in coastal area in Tanjung Pasir Village. The research methods performed with interview, observation, and documents study. Field result also analyzed by participation rural appraisal (PRA) and continued by SWOT analysis and coastal tourism development identification strategy. The result of this research is two strategic issue: at first, Tanjung Pasir Village has some tourism development tr iggers like Tanjung Pasir Beach, Crocodile Captivity Park, Tanjung Pasir Resort, crossing access tourism island, Mangrove Park, and Seafood Culinary; secondly, main problem in tourism development is in local capacity of human resources (especially in qualit y standard enhancement of tourism components and local empowerment). Based on the field result, it necesarry to improve tourism development components like attraction, amenity (accommodation), accessibility, and anciliary. After it is done in strategic issue mapping, it also necessay to coordinating all of stakeholder in collaboration scheme to develop tourism area in Tanjung Pasir Village to make welfare society. The implication of this research are contribute in tourism developing strategy by Tangerang Regency Government.
A Means to Culmination Poetry to Education
Authors:   Directorate General of Education of Kerbela,Ministry of Education of Iraq, Abbass Kadhim Dahwi
Published: March 2021

Poetry pedagogy is a postmodern educational revival that tends to utilize this genre in promoting the standard of education in many countries including USA, UK, Canada and Ireland. It emphasizes retrieving the role that poetry played, in line with other genres of literature, in keeping nations' traditions and history alongside with its role in developing students' informative capacities due to the pleasure it fosters in listeners and readers mixed with zealous feeling for better production and immediate and permanent reaction as far as its ascendency on all senses is concerned. The present study explores the role of poetry in the above domain and demonstrates its ability in bypassing intellectual rigidity, idleness and the robotizing of the students that afflicted educational systems all over the world. It highlights that poetry is a double- edged sword in establishing a strong linguistic foundation, and its brevity appropriates people's occupations as far as intensity and abundance of meaning are concerned. The study also shows the role of poetry in deepening thinking and transforming it from extrinsic to intrinsic as well as promoting the standard of language in students concerning structure and vocabulary. In addition, texts of different themes indicate that the emotional interaction with poetry can repel monotony and consolidate interest and intensification. Moreover, the accompanying sense of enjoyment is not yet complete and satisfactory unless the covenant is consolidated by a sufficient teacher. Therefore, the present study describes the successful teacher intended to teach poetry and the way with which he tackles this activity.
Laboratory information systems in internal quality control of a cardiac surgery hospital
Authors: Bockeria Leo A. , Satyukova Anna S. , Yarustovskiy Mihail B. , Tetvadze Inga V. , Kupryashov Aleksei A. , Shcherbak Anastasia V. , Kirtbaya Lana N. , Smirnov Ivan S. , Grankov Andrey V.
Published: March 2021

Introduction. In recent years, laboratory information systems (LIS) have become an element of medical institutions’ work, providing high quality and efficiency of clinical activities. Laboratory diagnosis plays a vital role in treating and preventing all known diseases, which requires compliance with specific quality criteria. Material and methods. A study was conducted with the historical control of the laboratory tests’ conditiona-lity before and after introducing LIS in the A.N. Bakulev National Medical Research Center of Cardiovascular Surgery. During 2018, quarterly an analysis of the reappointments of the following groups of laboratory tests was carried out: hematological test, immunochemical analysis, biochemical blood test, hemostasis system (coagulogram), platelet aggregation with ADP. Unfounded recognized studies assigned more than once for 48 hours in the absence of clinical justification. Results are provided using standard descriptive statistics methods. Results. After the work carried out in the fourth quarter, there was a decrease in the total number of appointments by 20% and a decrease in studies performed in terms of one patient. Conclusion. The introduction of LIS made it possible to obtain a tool for quantitative and qualitative analysis of the validity of the purpose of laboratory research and conduct an economic analysis of the results. The data obtained were subsequently used to develop laboratory profiles, allowing to continue the optimization of this area and the implementation of lean technologies in the clinic. Also, the data obtained made it possible to evaluate the knowledge and application of clinical recommendations to manage patients with various pathologies. During the verification of the results and analysis of the doctors’ explanatory notes, the laboratory process’s most compromised stages were identified.
Changes in mortality, life expectancy and the rate of aging in the XX century: possible causes
Authors: Dontsov Vitaly I.
Published: March 2021

Introduction. The rapid aging of the world and Russian population and the associated medical, demographic, and socioeconomic problems determine the increased interest in the issue of aging. Aim and objectives. to study the features and causes of changes in age-related mortality, life expectancy (LE), and aging in Russia in the second half of the XX century compared to other countries. Material and methods. We used the Human Mortality Database survival tables to estimate the expected and maximum life expectancy. The aging rate was calculated using the Gompertz-Makeham formula and the increment of total mortality. Graphs were built using Microsoft Office Excel’s standard tools and the computer program Aging of Populations developed by us. Results. Until the middle of the XX century, significant aging rate changes did not accompany a sharp increase in Le. Later with a relatively small increase in LE, it decreases sharply. Deceleration of aging was observed for all studied countries (from 12 to 36 for different available historical periods) for all studied parameters and progresses to the end of the studied period. For Russia, the decline in the aging rate that began simultaneously 7 with other countries in 1960-1970's slows down and is restored only by 2000. Discussion. Improvements in living conditions and health outcomes lead to an increase in the proportion of the elderly population structure. However, these same processes reduce the rate of individual aging. Improving medical and social care for retired people reduces their mortality rate. Still, it produces a phenomenon of delayed mortality in later ages (the phenomenon of inversion of centenarians’ total mortality - from reduced to increased). Nevertheless, the use of the mortality rate increment indicator shows that the decline in the aging rate for centenarians persists. Conclusion. The identified trends in mortality are useful for developing areas of preventive and socio-medical impact on the population’s health.
Evaluation of the activity of antioxidant enzymes during chronic oral administration of a technical product derived from triazoles in the rats
Authors: Rakitskii Valery N. , Chkhvirkiya Elena G. , Epishina Tatiana M.
Published: March 2021

Introduction. Entering the body in various ways, pesticides, being biologically highly active compounds, can pose a real danger to public health, causing changes in non-specific biochemical reactions of metabolism occurring in all living cells. The antioxidant system, represented as a balance of lipid peroxidation and antioxidant protection (POL - AOZ), is one of the metabolic regulatory mechanisms of these responses. The aim of the study was to study the effect of a technical product (TP), a derivative of triazoles, on the acti-vity of antioxidant enzymes in the rat body, under its repeated oral intake in a chronic 12-month experiment. Material and methods. A chronic (12 months) experiment was performed on male rats with a bodyweight of 200-210 g at the beginning of the study. Tested doses: 5.0, 16.0 and 55.0 mg/kg of body weight (1 control and 3 experimental groups, 20 individuals each). In the dynamics of the experiment, after 1, 3, 6 and 12 months, the state and behavior of animals, water and food consumption were observed. Changes in the enzymatic indices of the body’s antioxidant defense system (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase) were registered. Results. It was found that TP at a dose of 5.0 mg/kg of body weight does not cause significant changes in the activity of antioxidant enzymes, doses of 16.0 and 55.0 mg/kg of body weight cause an increase in the activity of superoxide dismutase (SOD) and a decrease in the activity of catalase in the body of experimental animals compared to control animals. Discussion. In the conducted chronic experiment, it was found that the studied TP at a dose of 5.0 mg/kg of body weight does not cause significant changes in the activity of the studied antioxidant enzymes in the body of rats. The introduction of TP at doses of 16.0 and 55.0 mg/kg of body weight causes a significant change in the activity of such antioxidant enzymes as SOD and catalase. Our results are consistent with the literature data, according to which the cell quickly reacts to oxidative stress by increasing the activity of SOD, and SOD is considered even as a stress protein synthesized in response to oxidative stress. Conclusions. The conducted research shows the feasibility of studying antioxidant enzymes’ activity in the mammalian body in sanitary and toxicological studies to increase the reliability of the developed hygienic standards of xenobiotics in environmental objects and food products.