Salt Promotes Inflammation: Mechanistic Insights
Authors: ROS Editorial Office 
Published: March 2022

It has been well established that high dietary salt intake promotes inflammation and contributes to the pathogenesis of many inflammatory disorders, especially cardiovascular diseases. Several recent studies published in prestigious journals have further elucidated the molecular pathways underlying high salt-induced inflammation, including identification of the involvement of mitochondrial electron transport chain and the Nrf2-SIRT3 signaling axis. These novel findings provide important mechanistic insights and offer potential opportunities for developing modalities for intervention of high salt-associated pathophysiological conditions.
(First online: March 1, 2022)
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