bluuebunny/crossref_metadata_2025 huggingface dataset:
Edukasi Narkoba Kepada Kader dan Karang Taruna di Kelurahan Landasan Ulin Tengah
Authors: Izma Hayatun , Intannia Difa , Lingga Herningtyas Nautika , Zainah Alya , Wiratama Bayu , Rahmi Fitriana , Kesuma Laode Muhammad Indra , Nahdiya Nahdiya
Published: October 2023

Penyalahgunaan narkoba semakin marak dan hingga kini masih menjadi permasalahan nasional yang belum teratasi. Pengguna narkoba berasal dari berbagai jenjang status sosial ekonomi mulai dari menengah bawah hingga menengah atas, tidak hanya orang dewasa namun sekarang menyebar hingga tingkat remaja dan anak-anak. Upaya pencegahan dan pemberantasan penyalahgunaan narkoba memerlukan dukungan dari semua lapisan Masyarakat. Kader dan karang taruna merupakan orang-orang terdekat dengan Masyarakat dan berperan penting dalam peningkatan kualitas kesehatan dan kesejahteraan Masyarakat. Kegiatan ini bertujuan untuk memberikan edukasi mengenai narkoba kepada kader dan karang taruna agar dapat memberikan edukasi kepada masyarakat lainnya, sehingga pencegahan dan pemberantasan penyalahgunaan narkoba di Masyarakat dapat berjalan. Rangkaian kegiatan yang dilaksanakan yaitu pretest, penyampaian materi dengan metode ceramah menggunakan media powerpoint, dilanjutkan sesi diskusi dan posttest. Berdasarkan evaluasi yang dilakukan melalui kuisioner pretest dan posttest menunjukkan adanya peningkatan pengetahuan peserta dari 84,6% menjadi 86,9%.Kata Kunci: Kaderisasi, Bahaya Penyalahgunaan Narkoba, MasyarakatDrug abuse is increasingly widespread and is still a national problem that cannot resolved optimally. Drug users range from lower to middle economic levels to upper socio-economic status, not only adults but also teenagers and children. Drug prevention and eradication efforts require support from all levels of society. Cadres and Karang Taruna are the people closest to the community and play a leading role in improving the quality of health and welfare of the community. The activity aims to provide drug education to cadres and Karang Taruna so that they can provide education to other communities so drug prevention and eradication can occur in society. The activities were a pretest, Provide education using lecture method with PowerPoint Presentation, a discussion session, and a posttest. Based on evaluations through pretest and posttest, it showed an increase in participants knowledge from 84.6% to 86.9%.
Kemampuan Bacillus thuringiensis untuk Mengendalikan Spodoptera frugiperda J.E. Smith
Authors: Jani Raden , Soedijo Samharinto , Liestiany Elly
Published: October 2023

Spodoptera frugiperda adalah hama utama yang menyerang tanaman jagung sehingga perlu dilakukan upaya pengendalian. Salah satu alternatif pengendalian menggunakan agensia hayati Bacillus thuringiensis (Bt). Pada penelitian ini penggunaan agensia hayati bakteri B. thuringiensis terhadap larva S. frugiperda. Penelitian ini bertujuan untuk mengetahui kemampuan dari bakteri B. thuringiensis dalam mengendalikan S. frugiperda untuk skala di laboratorium. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 4 perlakuan dan 6 kali ulangan. Perlakuan menggunakan dosis 2 ml, 2,5 ml dan 3 ml bakteri B. thuringiensis serta sebagai pembanding yaitu air steril yang bertindak sebagai kontrol dalam penelitian ini. Pengamatan mortalitas dilakukan setiap 12 jam selama 96 jam. Setiap ulangan diinfestasikan 10 ekor larva S. frugiperda sehingga didapatkan 240 ekor larva S. frugiperda pada setiap unit satuan percobaan. Hasil penelitian ini menunjukkan bahwa agensia hayati bakteri B. thuringiensis pada dosis 3 ml memiliki kemampuan  patogenisitas terhadap mortalitas S. frugiperda dengan persentase yaitu sebesar 23,3% dan memilki nilai Lethal Time dengan waktu terbaik yaitu 9,3 hari untuk mematikan 50% S. frugiperda.
Pengujian Beberapa Varietas Cabai Besar (Capsicum annuum L.) Terhadap Lama Periode Inkubasi dan Tingkat Ketahanannya Terhadap Layu Bakteri Ralstonia solanacearum
Authors: Raihanah Rizka , Fitriyanti Dewi , Liestiany Elly
Published: October 2023

Large chilies (Capsicum annuum L.) are one of the important vegetable commodities. One of the Plant Pest Organisms that causes large chili production to decline is bacterial wilt disease. Bacterial wilt disease in chili cultivation is usually caused by the bacteria Ralstonia solanacearum. Ralstonia solanacearum is a soil-borne pathogen that is able to live in soil without a host. This bacterium has a relatively large number of hosts in the form of horticultural plants, ornamental plants and weeds. This study aims to test five varieties of large chili plants (Capsicum annuum L.) against bacterial wilt disease (Ralstonia solanacearum). Research was carried out at the Phytopathology Laboratory and at the Banjarbaru Agricultural Faculty Experimental Farm. This research used 5 varieties, namely Limosin, Beton F1, Pilar F1, Darmais F1 and Gada Mk F1 with 4 replications. The Limosin variety has the longest incubation period, namely 39 days, while the Pilar F1 and Gada Mk F1 varieties have the fastest incubation period, namely 30 days. The varieties Beton F1, Pilar F1 and Gada Mk F1 show resistant varieties with percentages of 15%, 10% and 5%, while the Limosin variety shows slightly susceptible varieties with a percentage of 50%.
The Main Research Directions in the Study of Regional Book Culture: on the Example of the Republic of Buryatia
Authors: Kuchmurukova E. A.
Published: October 2023

In recent years, the number of research on regional book culture has increased. This trend can be traced in Buryatia, where, on the contrary to the consistency of surveys carried on during the Soviet period, they are scattered today. The lack of the holistic idea of the main directions to study Buryatia book culture in different historical periods dictates the need to summarize information on the research carried out, to determine the degree of development of the scientific problem. The purpose of the article is to analyze published sources reflecting various aspects of the development of Buryatia book culture. As a result, a historiographic analysis of scientific works devoted to the history and modern state of book publishing, book distribution, printing industry, republican periodicals was carried out, the research activities of the Department of Library and Information Resources of VSGIK in this direction were described. Summing up the results of many years of work on the study of the topic made it possible to identify gaps and determine the prospects for its further development.
About the Reading Circle of the Siberian Old Believers on the Example of the Collection B-777
Authors: Esipova V. A.
Published: October 2023

The purpose of the article is to reconstruct the reading and writing practices of the Siberian Old Believers of the 18th century and determine the place of Old Russian texts in their reading repertoire. Methods of textology and codicology are used. The article considers one of collections copied in the Siberian Old Believer environment at the end of 18th century – Old Believer collection B–777 from the Tomsk State University Research Library. On the basis of scriber’s records the conclusion is made about the place where collection was created: it is Altay and the south of Western Siberia. The composition of the collection is analyzed, the main groups of texts included in it are listed. It is proved that the collection belongs to the well–known “library in one binding” model, which allows reconstructing the reading circle of its scriber, as well as the owner. It is shown that along with later texts, texts of Old Russian tradition are also presented. It is concluded that the texts of Old Russian tradition were not always reproduced in the later Old Believers communities as a result of a continuous handwritten tradition, and were sometimes copied from books of the Cyrillic print. The creative nature of the reader’s practices of the collection owner, who significantly revised the text of Cyril of Turov, is substantiated.
Scientometrics Today: Analysis of the Publication Activity of a Scientific Organization in the Russian Science Citation Index
Authors: Prokofieva Yu. D. , Peksheva M. A.
Published: October 2023

Due to the limited access to the Web of Science and Scopus, scientific libraries are forced to look for alternative sources of bibliometric information. There has appeared the need to revise the methods and tools for conducting scientometric research and assessing scientific activity in general. Specialists’ attention to the Russian Science Citation Index (RSCI) has especially increased, which now most fully reflects the Russian document flow on scientific publications and has the analytical capabilities necessary to work with bibliometric indicators. In the Central Scientific Library of the Ural Branch of the Russian Academy of Sciences (UB RAS), the methodology for scientometric analysis of the publication activity of scientific organizations of UB RAS has been reoriented to RSCI. The purpose of the study is to analyze the publication activity of a UB RAS scientific organization and test the RSCI tools for solving scientometric problems according to the developed methodology. The study revealed the need to revise the analysis criteria and methods of obtaining data according to the RSCI architecture. Conclusions are drawn on the effectiveness of RSCI tools for the purposes of the methodology, the correctness of the data obtained, and actions are proposed to improve the functionality of the system.
Analisis Keefektifan Instagram (@jinawigreens) Sebagai Media Komunikasi Pemasaran Digital Jinawi Farm Hidroponik Karanganyar
Authors: Pravina Tiara Octari , Widiyanti Emi , Permatasari Putri
Published: October 2023

Abstrak
Jinawi Farm Hidroponik menjadi salah satu usaha yang mengembangkan produk pertanian hidroponik menjadi olahan pangan sehat berupa salad sayur. Tentunya diperlukan sebuah kegiatan komunikasi pemasaran dalam pengembangan usahanya, salah satunya melalui media sosial Instagram (@jinawigreens). Oleh karena itu, perlu dilakukan pengukuran keefektifan Instagram tersebut. EPIC Model digunakan sebagai alat ukur keefektifan dalam penelitian ini, yaitu model yang mengukur keefektifan dengan mengunakan pendekatan komunikasi melalui empat dimensi kritis (empati, persuasi, dampak, dan komunikasi). Penelitian ini bertujuan untuk 1) Menganalisis karakteristik pesan media sosial yang ada di Instagram @jinawigreens. 2) Menganalisis keefektifan media sosial Instagram @jinawigreens berdasarkan EPIC Model. 3) Menganalisis pengaruh karakteristik pesan media sosial Instagram @jinawigreens terhadap keefektifan Instagram sebagai media komunikasi pemasaran digital Jinawi Farm Hidroponik berdasarkan EPIC Model. Hasil penelitian menunjukkan bahwa tingkat keefektifan Instagram yang diperoleh dari hasil EPIC Rate sebesar 3,74 yaitu berada pada rentang skala keputusan 3,41 – 4,20 yang memiliki makna efektif.
Kata Kunci: Komunikasi Pemasaran Digital; Instagram; Hidroponik.
Efektivitas Komunikasi Pemasaran Produk Gapoktan Mitra
Authors: Hanifa Distantya , Winarno Joko , Suminah Suminah
Published: October 2023

Penelitian ini bertujuan untuk mendeskripsikan efektivitas komunikasi pemasaran produk dan  mendeskripsikan variabel serta menganalisis pengaruh periklanan, promosi penjualan, personal selling (pejualan perseorangan), direct marketing(penjualan langsung), dan word of mouth baik secara simultan dan parsial terhadao efektivitas komunikasi pemasaran produk di Roko Tani Indonesia Center Yogyakarta. Penelitian menggunakan metode kuantitatif dengan pemilihan sampel secara non-probably sampling. Data dianalisis melalui analisis deskriptif, verifikatif, uji asumsi klasik, dan regresi linier berganda. Hasil menunjukkan efektivitas komunikasi pemasaran produk gapoktan mitra pada Toko Tani Indonesia Center Yogyakarta meliputi komponen pengetahuan dan behaviour change secara keseluruhan berada pada kategori tinggi. Variabel promosi penjualan, personal selling, direct marketing, dan word of mouth berpengaruh signifikan terhadap efektivitas komunikasi pemasaran produk gapoktan mitra pada Toko TaniIndonesia Center Yogyakarta. Sedangkan variabel periklanan tidak berpengaruh. Nilai koefisien determinasi (R2) sebesar 0,874, artinya 87,4% efektivitas komunikasi pemasaran produk gapoktan mitra pada TTIC Yogyakarta dapat dijelaskan oleh variabel periklanan, promosi penjualan, personal selling, direct marketing, dan word of mouth.
The Influence Concept Attainment Learning Model on Students Argumentative Skills and Concepts Understanding on Angiosperm Material
Authors: Ramdhani Fadhil , Suprapto Purwati Kuswarini , Ali Mufti
Published: October 2023

Students need their own arguing skills in learning process. Based on the observation, it is known that not all students have the same courage to express their opinions, both verbally and written. This leads to a lack of understanding of the media design content being studied by education participants. The application of the Concept Attainment learning model is expected to train students how to construct their own concepts and be able to express them verbally. This study aims to determine the effect of concept attainment learning model on students' argumentative skills and concept understanding of angiosperms subject in class X MIPA SMAN 5 Tasikmalaya. This study used a quasi-experimental research method with a research design Nonequivalent Control Group Design. The population in this study were all students of X MIPA SMAN 5 Tasikmalaya of seven classes with a total number of 245 students. The sampling technique used was purposive sampling, with the samples used class X MIPA 3 as the experimental class and X MIPA 5 as the control class with a total number of 72 students. The instruments used in this study consisted of 5 argumentative ability test questions and 10 concept understanding questions. The data analysis technique used in this research is parametric statistical data analysis technique. Data is processed by conducting prerequisite analysis in the form of a normality test, homogeneity test, and hypothesis testing using one way ANOVA test. The results showed that there was a significant effect of the concept attainment learning model on students' argumentative skills and concept understanding with a significance value of (0.000). Based on these positive results, it can be used as a reference for educators to use concept attainment models that support teaching and learning activities.
The Influence of Science Skills Through Scientific Learning Model In Biology Learning: A Review Study
Authors: Imtihana Ezif Rizqi , Restiana Restiana
Published: October 2023

Scientific learning is a common approach that is quite effective in learning, especially in learning biology.  This research was conducted with the aim to find out (1) the influence of science skills through scientific learning models, (2) types of scientific learning models that affect students' science skills, and (3) natural science topics using scientific learning models that affect students' science skills.  This research was a meta-analysis study with a qualitative approach that adopted a literature review method by Durst & Edvardsson consisting of the following 4 steps. 15 articles were selected from 27 articles published in the last 5 years (2018-2022). The research article was searched using the Educational Resources Information Center (ERIC), SINTA Indonesia online database. Results of these analyses show that science skills affected through scientific learning model are 3C, thinking skill, literacy skill, and science process skill. These science skills are influenced through scientific learning model by project-based learning, problem-based learning and discovery learning. Biology topics used in this research are environment, plantae, histology, endocrine system, animal kingdom, ecosystem, and biodiversity; environment is the most commonly used topic in science learning.
Increasing Student’s Cognitive through Problem Based Learning
Authors: Adjiningsih Riris Sejati , Sulistyarsi Ani , Sukimarwati Juli
Published: October 2023

Based on the observation in the class of X F at SMAN 6 Madiun, it showed that students lack of curiosity, low desire in asking and expressing opinions, and lower enthusiasm for reading sources of information. Through the classroom action, this study aim to increase students’ cognitive on biotechnology with problem based learning (PBL) model. This research was conducted with three cycles. The cycle consists of four stages such as planning, action implementation, observation, and reflection. The target of study amounted to 35 students of class X F. The data collected through pre- and post-test, students’ questionnaires, observation notes and interviews. The data were analyzed descriptively. The result found that after using problem based learning, the students’ cognitive result percentage increased, from 1st cycle 51% to 2nd cycle 60% and 3rd cycle is 86%. Based on the questionnaire data, 49% of students strongly agree that the problem based learning model can help in learning biotechnology. The improvement of percentages cognitive result show the higher number of students complete the material increased in each cycle
ANALISIS RISIKO PRODUKSI USAHATANI PADI SAWAH DI DESA SUNGAI BADAK KECAMATAN MESUJI KABUPATEN MESUJI
Authors: Asih Langgeng Tri , Saty Fadila Marga , Noer Irmayani
Published: October 2023

Rice is a staple food source for the Indonesian population. Rice commodity is an agricultural commodity that has a high enough risk and poses a threat to the welfare of rice farmers. The Badak river village is one of the villages that has superior agricultural commodities in Mesuji Regency in the form of rice plants. This research aims to identify the sources of risk faced by farmers in Sungai Badak Village, Mesuji District, Mesuji Regency and analyze the magnitude of the risk impact. The results of the analysis showed that the main sources of risk during planting season 1 were Plant Pest Organisms (OPT) and plant diseases, while the main risk sources in planting season 2 were weather / climate factors. Meanwhile, using the Z-Score shows a risk probability of 30 percent in planting season 1 and 26 percent in planting season 2, while the analysis using the VaR method, the resulting risk impact in planting season 1 is IDR 3,646,801 per hectare, while the risk impact on planting season 2 amounting to IDR 4,030,634, - per hectare.
KUALITAS LAYANAN DAN THEORY OF PLANNED BEHAVIOR: DAMPAK PADA KEPUASAN PELANGGAN DALAM LAYANAN DRIVER ONLINE MAKANAN DI MASA PANDEMI COVID-19
Authors: Prasanti Tissa Permata , Aprilia Anisa , Dewi Heptari Elita
Published: October 2023

Masyarakat menjadi lebih konsumtif dalam hal membeli produk, terutama makanan, sebagai akibat dari pandemi COVID-19. Kondisi ini juga disebabkan oleh anjuran pemerintah agar masyarakat tidak melakukan aktivitas di luar rumah. Masyarakat tetap dapat memenuhi kebutuhan pangannya dengan menggunakan jasa pengiriman online. Tujuan penelitian adalah  menganalisis kualitas layanan dan planned behavior terhadap kepuasan pelanggan dalam layanan driver online makanan di masa pandemi COVID-19. Lokasi penelitian berada di Kota Malang, Jawa Timur dengan 62 responden yang diambil dengan purposive sampling. Teknik analisis data menggunakan metode SEM-PLS (Structural Equation Modelling-Partial Least Square) dengan software WarpPLS 7.0. Hasil penelitian menunjukkan bahwa variabel kualitas layanan berpengaruh signifikan terhadap kepuasan pelanggan. Variabel niat sebagai variabel mediasi memiliki pengaruh signifikan terhadap kepuasan pelanggan. Variabel sikap dan norma subjektif berpengaruh signifikan terhadap niat individu. Sedangkan, variabel kontrol perilaku persepsi tidak berpengaruh signifikan terhadap niat. Berdasarkan temuan penelitian, para pelaku usaha sejenis diharapkan dapat melakukan peningkatan kualitas layanan, seperti memperhatikan rating dari pelanggan dan menghimbau driver untuk mengikuti SOP (Standart Operating Procedure). Kemudian, pelaku usaha dapat meningkatkan kegiatan promosi dan memberikan kupon diskon dengan tujuan untuk terciptanya mouth to mouth di lingkungan masyarakat. Semakin individu percaya dan yakin terhadap jasa atau produk yang digunakan, maka akan terciptanya sebuah niat individu untuk melakukan pembelian produk. 
KONSUMSI MINUMAN HERBAL DAN PROBIOTIK DI KALANGAN MAHASISWA PADA MASA PANDEMI COVID-19
Authors: Halim Indah Oktavia , Rasmikayati Elly , Saefudin Bobby Rachmat
Published: October 2023

Drinks are fluids that are needed by the body, these drinks are categorized into healthy drinks and sweet drinks. Drink consumption changed during the Covid-19 pandemic, which is a new virus originating from Wuhan, China with a very fast spread that has an impact on the economy, changes in social relations, and changes in lifestyle. Efforts that can be made to reduce the spread of the virus is to maintain the body's immunity, one way is by consuming healthy drinks. Although healthy drinks for students during the pandemic have increased, the consumption of sweet drinks is still favored by students and until now there are still few studies that discuss the habits of consuming healthy drinks in students. The purpose of this study was to determine  of consumption of healthy drinks both before and during the Covid-19 pandemic. This study uses a quantitative descriptive design with a survey method. The study was conducted on students of the Faculty of Agriculture, Padjadjaran University batch 2020. The analytical method used was descriptive statistics with column diagrams, frequency distribution tables and cross tabulations. The results showed that there was an increase in the consumption of healthy drinks, namely herbal drinks and probiotic drinks during the Covid-19 pandemic.
PENGGUNAAN ZPA HASIL EKSTRAK KULIT POHON RAMBUTAN RAPI’AH UNTUK PEWARNAAN BATIK CELUP MENGGUNAKAN TEKNIK FIKSASI
Authors: MR Santosa Kaffah imanuddin , Listiani Sri
Published: October 2023

Dalam perkembangannya batik menjadi sebuah trend yang tidak hanya menjadi sebuah pakaian yang formal, di era kontemporer batik banyak digunakan menjadi berbagai model busana keseharian. Batik juga merupakan warisan budaya yang mengandung makna dari setiap visualnya. Di Indonesai batik dikenal memiliki beragam motif yang berasal dari beberapa daerah berbeda. Batik adalah sebuah teknik juga dikenal sebagai pewarnaan kain serat alami dengan menggunakan teknik celup rintang. Bagian kain menjadi bercorak karena pada waktu dicelupkan dalam cairan warna, terdapat bagian yang sengaja dirintangi. Bagian kain yang dirintangi itulah yang menimbulkan corak motif batik. (Tocharman, 2009) Pewarna batik umumnya menggunakan zat kimia yang dapat memberikan dampak negatif pada lingkungan. Namun karena sifatnya yang praktis dan berorientasi pada kuantitas produksi menjadi media pewarnaan konvensional. Indonesia merupakan negara yang kaya akan sumber daya alamnya. Kondisi ini menuntut kita untuk dapat mengeksploitasi dan mengeksplorasi sumber daya alam secara benar. Salah satu sumber daya alam yang dapat digunakan dalam industri batik adalah zat pewarna alam (ZPA). Proses penggunaan warna-warna alam dalam teknik batik ternyata sudah dilakukan oleh nenek moyang kita secara turun temurun sampai ditemukan warna sintetis yang dipandang praktis dan ekonomis. Pohon rambutan merupakan pohon yang banyak ditemukan di Indonesia. Disamping buah, penulis berasumsi banyaknya getah yang terkandung dalam batang pohon rambutan rapi’ah, maka kulit pohon rambutan rapi’ah dapat dimanfaatkan sebagai Zat Pewarna Alam pada batik. Penelitian ini menggunakan metode kualitatif deskriptif dengan eksperimen terhadap kain mori yang biasa digunakan sebagai kain batik untuk melihat hasil warna yang dihasilkan dari ekstrak pohon rambutan rapi’ah dengan menggunakan beragam fiksasi.
Actual problems of management of the radiology diagnostics service of the primary level of health care
Authors:   State Budget-Funded Health Care Institution of the City of Moscow “Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department”, Shulkin I. M. , Vladzimirsky A. V. ,   State Budget-Funded Health Care Institution of the City of Moscow “Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department”, Shults E. I. ,   State Budget-Funded Health Care Institution of the City of Moscow “Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department”, Akhmetov R. N. ,   State Budget-Funded Health Care Institution of the City of Moscow “Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department”
Published: October 2023

The main problems of the organization of the work of the radiation diagnostics service and the possibilities for their solution provided by the tools of information systems are considered. The organizational tasks that need to be provided for in the digitalization of healthcare are formulated. The analysis of changes in the organizational and managerial approach to ensuring the work of the diagnostic department is carried out. A decisive role in the development of modern healthcare is played by a systematic approach to the digitalization of the industry and the creation of digital infrastructure in accordance with current requests for operational management.
Improvement of the blood donor system in russia: the case of belgorod and kursk regions.
Authors:   Graduate School of Management, Sklyar T.M. , Kotlyarova M.V. ,   Graduate School of Management
Published: October 2023

The development of donation of blood and its components is a strategic direction of the healthcare system. Active work on attracting donors and forming a base of regular donors serves as an important factor in the system of providing the population with donor blood components. The research question is to identify motives, incentives and barriers to blood donation in Russia. This issue is considered on the example of Belgorod and Kursk regions, where the number of blood donors and its components per 1000 population is lower than the national average. The aim of the article is to develop recommendations for the development of blood donation and its components in the Russian Federation. The study uses sociological, statistical, and econometric research methods. The article is based on the analysis of annual reports prepared for FMBA of Russia by blood service organizations of Belgorod and Kursk regions from 2019 to 2021. The method of collecting primary information is a survey of blood donors and its components and the population of Belgorod and Kursk regions, conducted in March-May 2022. Based on the results of the survey it is shown that the effectiveness of advertising campaigns to promote voluntary and non-remunerated blood donation and its components is not high enough, donor traffic light is not currently an effective tool to inform the population about the current status of blood stocks and need for individual components of donor blood. A social portrait of a donor, which is reasonable to use for the adjustment of marketing activities in terms of increasing the coverage of the target audience, has been compiled. The article formulates recommendations for the development of donation of blood and its components.
Rilke en Álvaro Cunqueiro
Authors: Mariño Francisco Manuel
Published: October 2023

Más conocido en el ámbito hispanohablante como prosista que como poeta —debido, tal vez, a que el género lírico fue más cultivado por él en lengua gallega—, Álvaro Cunqueiro es un escritor singular, cuya literatura tiene un carácter universalista, transido de múltiples referencias literarias, entre las que el nombre de Rilke, implícita o explícitamente, ocupa un lugar destacado y aparece prácticamente, en todos los géneros por él cultivados, especialmente en la poesía y en el artículo periodístico. Este trabajo mostrará el alcance de esa presencia rilkiana y las traducciones que el autor gallego llevó a cabo del praguense
Géneros textuales en materia de migración: la traducción a la lengua árabe desde el francés y el alemán
Authors: El Herch Moumni Sabah
Published: October 2023

El presente trabajo abordará el estudio de los géneros textuales presentes en la documentación que toda persona migrante o desplazada ha de emplear en los servicios de extranjería, ya sea para resolver situaciones de residencia temporal o definitiva, o para solicitar la condición de refugiado o asilado. En una primera parte del trabajo analizaremos el género textual en su lengua original; una segunda parte nos llevará a determinar la información disponible en árabe de documentos administrativos y legales en países francoparlantes y germanoparlantes para dilucidar en qué medida estas traducciones son efectivas y útiles a personas desplazadas o migrantes para realizar los trámites oportunos en materia de extranjería, migración, refugio o asilo.
Eva Parra Membrives In Memoriam
Authors: Balbuena Torezano María del Carmen
Published: October 2023

Presentación a cargo de la editora de la revista de la sección-homenaje a la Profesora Eva Parra Membrives.
NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting
Authors: Sharma Swati , Ehrlich Marcelo , Zhang Manqi , Blobe Gerard , Henis Yoav
Published: October 2023

Endothelial cells express neuropilin 1 (NRP1), endoglin (ENG) and vascular endothelial growth factor receptor 2 (VEGFR2), which regulate VEGF-A-mediated vascular development and angiogenesis. However, the link between complex formation among these receptors with VEGF-A-induced signaling and biology was unclear. Here, we quantified surface receptor interactions by IgG-mediated immobilization of one receptor, and fluorescence recovery after photobleaching (FRAP) measurements of the mobility of another coexpressed receptor. We observed stable ENG/NRP1, ENG/VEGFR2, and NRP1/VEGFR2 complexes, which were enhanced by VEGF-A. ENG augmented NRP1/VEGFR2 interactions, suggesting formation of tripartite complexes bridged by ENG. Effects on signaling were measured in murine embryonic endothelial cells expressing (MEEC+/+) or lacking (MEEC-/-) ENG, along with NRP1 overexpression or knockdown. Optimal VEGF-A-mediated phosphorylation of VEGFR2 and Erk1/2 required ENG and NRP1. ENG or NRP1 increased VEGF-A-induced sprouting, becoming optimal in cells expressing all three receptors, and both processes were inhibited by a MEK1/2 inhibitor. We propose a model where the maximal potency of VEGF-A involves a tripartite complex where ENG bridges VEGFR2 and NRP1, providing an attractive therapeutic target for modulation of VEGF-A signaling and biological responses.
Using Artificial Neural Network for Forecasting PM2.5 Levels in a Prominent Industrial and Historically Significant Urban Center in Iran: Evaluating Health Implications
Authors: bardshahi ali mohammadi , Jaafarzadeh Neemat , Tabatabaie Tayebeh , Amiri Fazel
Published: October 2023

There has been a scarcity of comprehensive studies that aim to predict both the levels of PM2.5 particles and their corresponding impacts on human health. To fill this gap, we developed an artificial neural network model and AirQ+ software to predict PM2.5 concentrations and assess their associated health effects. The ANN model utilized five distinct input parameters, specifically wind velocity, wind orientation, atmospheric temperature, relative moisture content, and PM2.5 levels, observed within the time frame of 2018 to 2019. The concealed stratum comprised a total of ten neurons, in addition to the presence of an output layer. The MLP neural network demonstrated strong correlations at each stage: 0.908 (training), 0.910 (validation), 0.914 (testing), and 0.907 overall. The RMSE was determined as 6.52 µg/m3 when evaluating the neural network, thus indicating the notable predictive precision exhibited by the multilayer perceptron (MLP) neural network when forecasting the concentration of PM2.5 particles. The AirQ+ software, created by the World Health Organization (WHO), was employed to assess the magnitude and consequences of PM2.5 concentrations. The average concentration of PM2.5 particles throughout the duration of the study was recorded as 26.5 μg/m3, which exceeds the recommended limit provided by the WHO by a factor of 5.3. The study estimated the proportions and numbers of deaths attributed to various conditions. Specifically, chronic obstructive pulmonary disease (COPD), ischemic heart disease (IHD), lung cancer (LC), stroke, and all-cause mortality accounted for approximately 11.67%, 15.02%, 13.25%, 15.225%, and 9.45% respectively. The estimated number of deaths were 19,195 for all causes, 10,063 for COPD, 564 for IHD, and 1,063 for lung cancer. The findings of this investigation demonstrate a high degree of reliability in the methodologies utilized. Through the utilization of these approaches, individuals in positions of authority and responsibility can aptly evaluate the cost-benefit analysis, leading to a reduction in human casualties and mitigating the economic burdens on society.
Epidemiological, Clinical and imaging features, and outcome of patients with Crisscross heart disease: A Systematic review of 46 published case reports
Authors: Ramadan Alaa , Roshdy Merna Raafat , Hamad Abdullah Ashraf , Refaey Neveen , Abdelazeem Basel , Essam Mohamed , Soliman Mostafa A , Abdelaziz Ahmed , Shieba Yusuf
Published: October 2023

Background and objectives
The crisscross heart (CCH) is a rare congenital cardiac abnormality defined by the crossing of the inflow streams of the two ventricles due to the heart's apparent twisting about its long axis. Despite being considered a defect, the CCH is more of a spatial than a functional aberration, so the heart can still work normally. The severity of this anomaly is determined by the difficulty of knowing the obscurity of the etiology, the lack of early diagnosis, and the exacerbation of its symptoms. The choice of optimal surgical interventions for managing complex heart defects leads to a marked reduction in morbidity and mortality incidence. We conducted this study to provide a summary and critical evaluation of the existing evidence knowledge on the nature of this defect and to emphasize the importance of early diagnosis.
Methods
We searched PubMed, Scopus, Web of Science, and Embase databases in addition to cross-checking against the bibliographies of retrieved articles to identify additional reports until September 15th,2022.
Results
Our inclusion criteria are met by 46 case reports, which include 101 patients of both sexes ≥1 month of age, published from 1974 to 2021. CCH was diagnosed in 45 (44.6%) females and 56 (55.4%) males with a median age of 66 months [interquartile range (IQR): 12-216 months] who came from 19 countries worldwide. The common clinical features manifested with dyspnea in 17 (16.8%), cyanosis in 39 (38.6%), and tachycardia in 12 (11.9%) patients. The most common associated congenital heart diseases were ventricular septal defect in 85 (84.3%) patients, double outlet right ventricle in 52 (51.5%) patients, and pulmonary stenosis in 62 (61.4%) patients. The Surgical intervention took place in 65.4% of the patients. A two-ventricle repair may not be possible in most patients, and these patients are prepared for a Fontan-type surgery.
Conclusion
Understanding this complex congenital heart disease allows clinicians to provide their patients with the best care and prompt intervention. Further investigation of the histopathology pictures and genetic sequences is needed to determine a clear pathogenesis.
Comparison of Home Exercise Under Supervision and Self Home Exercise in Pregnant Women with Gestational Diabetes: Randomized Controlled Trial
Authors: Menek Merve Yılmaz , Kaya Ayse Kavasoglu
Published: October 2023

Objective Exercise programs at home are successful in treating gestational diabetes by controlling blood glucose. The aim is to compare the efficacy of the self-directed home exercise program, the standard care alone and the supervised home exercise program in pregnant women with gestational diabetes on blood glucose, quality of life and pregnancy outcomes.
Methods This randomized, parallel, single-blind study included forty-five pregnant women who were 24-28 weeks of gestation. Participants were randomly divided into the supervised home exercise group (SHEG), home exercise group (HEG) and control group (CG). While the home exercises program was taught and controlled by a physiotherapist in SHEG, the home exercise brochure was given without any training by the gynecologist in HEG. Control group maintained their usual daily care. The home exercise intervention included low to moderate structured exercise performed three days per week for 8 weeks. Their glucose responses, quality of life and pregnancy outcomes were assessed pre- and post intervention.
Results Fasting glucose and 2 h postprandial glucose levels were improved statistically in SHEG and HEG groups after intervention (p<0.05). Differences in SHEG were statistically higher than HEG (p<0.017). When the HEG and CG were compared, there was no superiority between the two groups in all outcome measures except the physical health. Additionally, there were no statistically significant differences in values of cesarean birth and preterm birth between groups (p>0.05).
Conclusions This study revealed that pregnant women should be under the supervision of physiotherapists while doing home exercises.
Clinical Trial Registration The trial was approved by the registration of ClinicalTrials.gov and registration number: NCT05195333.
Mendelian randomization analyses of genetically predicted circulating levels of cytokines with risk of Inflammatory bowel disease
Authors: liu xianqiang , Li Dingchang , Gao Wenxing , Zhao Wen , Chen Peng , Liu Hao , Zhao Yingjie , Dong Guanglong
Published: October 2023

Objective
The literature has previously reported the associations between inflammatory bowel disease (IBD) and certain inflammatory cytokines, such as CRP, IL-1, and TNFα. To additionally evaluate the causal relationships between 41 inflammatory cytokines and IBD, a Mendelian randomization (MR) study was conducted.
Methods
The two-sample MR investigation utilized data from three large publicly available genome-wide association studies (GWAS) on IBD, ulcerative colitis (UC), and Crohn's disease (CD) genetic variants. Additionally, inflammatory cytokine data from a GWAS meta-analysis, including 8,293 healthy individuals, were incorporated into the study. Causal relationships between exposures and outcomes were predominantly determined utilizing inverse variance-weighted methods. To evaluate the heterogeneity, pleiotropy, and stability of these genetic variants, the MR-Egger intercept test, Cochran's Q test, and leave-one-out sensitivity analysis were conducted.
Results
The findings revealed that IL13 was linked to an elevated risk of IBD, UC, and CD, while MIF demonstrated a correlation with an elevated risk of CD. Conversely, TNF-related apoptosis-inducing ligand (TRAIL) was linked to a decreased risk of IBD and UC. Additionally, reverse MR analyses revealed that IBD was correlated with elevated levels of Monokine Induced by Gamma Interferon (MIG) and Stromal Cell-Derived Factor-1α (SDF1A), while UC showed an association with elevated levels of MIG and IL10. The CD was linked to elevated levels of stem cell factor (SCF) and decreased levels of TNF-β.
Conclusion
In the MR study, three upstream regulatory factors and five downstream regulatory factors were identified for IBD and its subtypes, providing avenues for developing new therapies for IBD.
Forecasting the Emission of Greenhouse Gases in the UK using SARIMA Model
Authors: Lalwani Praneya , Shetty Ishita
Published: October 2023

Earth’s climate change is an important and urgent issue, and most researchers believe it is caused by greenhouse gas emissions. Carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) trap heat in the atmosphere, raising the temperature of our planet Human activity is the main source of greenhouse gases, including the burning of fossil fuels for energy, deforestation, and agriculture, all contribute to GHG emissions Earth’s temperature due to the accumulation of greenhouse gases (GHGs) in the atmosphere, and resulting in rising sea levels, frequency and intensity of heat waves, droughts, floods and in excess weather events. India has seen a sharp rise in greenhouse gas emissions in recent decades and was the third largest emitter of greenhouse gases in the world according to the Global Carbon Project In contrast, the United Kingdom has worked aggressively to reduce greenhouse gas emissions in recent years. The objective of this study, is to provide a composite time series approach, to estimate GHG emissions for various industries producing greenhouse gases contributing to climate change. We used estimated greenhouse gas emission data available for the UK, which occurred in 1990. We subsequently conducted an exploratory data analysis to study the contributions to the total GHG emissions observed suggests that in the energy supply, it accounts for about 40% of total emissions. Furthermore, the study shows that greenhouse gas emissions decreased significantly in the years following the implementation of policies to increase energy efficiency Compared to emissions in the case of the UK to those in India, we gained a better understanding of emission norms in India and identified areas that require improvement.
Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis
Authors: Shinohara Akira , Sampathkumar Arivarasan , Ito Masaru , Fujita Yurika
Published: October 2023

DNA double-strand breaks (DSBs) activate DNA damage responses (DDR) in both mitotic and meiotic cells. Meiotic DSBs induce homologous recombination monitored by a meiotic DDR called the recombination checkpoint for the pachytene exit in meiotic prophase I. In this study, we showed the essential role of a single-stranded DNA (ssDNA) binding protein, Replication protein-A (RPA), in the maintenance of the recombination checkpoint during S. cerevisiae meiosis. The depletion of an RPA subunit, Rfa1, in a recombination-defective dmc1 mutant, fully alleviates the pachytene arrest with the persistent unrepaired DSBs. RPA depletion downregulates a meiosis-specific CHK2 homolog, Mek1, which in turn activates Ndt80 transcriptional activator for pachytene exit. These support the idea that RPA is a sensor of ssDNAs for the activation of meiotic DDR. Rfa1 depletion also accelerates the prophase I delay induced by the zip1 mutant defective in both chromosome synapsis and the recombination, suggesting that the accumulation of ssDNAs rather than defective synapsis triggers prophase I delay in the zip1 mutant.
Biochemical and Histoarchitectural Evaluation of 4-Vinylcyclohexane Induced Ovarian Cancer Against Alpinia Purpurata (Vieill). K. Schum
Authors: CHITHAMONY ARUL RAJ , PALNIRAJAN ANUSOORIYA , RAJU MANIKANDAN VANI , CHANDRASEKARAN MEENAKSHI KANIYUR , AHALLIYA RATHI MUTHAIYAN , DUGGANABOYANA GURUKUMAR , KANNIAPPAN GOPALAKRISHNAN VELLIYUR
Published: October 2023

Objective Alpinia purpurata is being studied for its potential to treat various conditions, including diabetes, arthritis, and tuberculosis. This research explores the impact of Alpinia purpurata (Vieill). K. Schum on ovarian cancer induced by 4-vinyl cyclohexane in Wistar albino rats.Materials and methods Five sets of 100-120g Wistar albino rats were assembled. Group 1 was the control group. Group 2 received intraperitoneal 4-vinyl cyclohexane (80 mg/kg) for one month. For two months, Group 3 was given A. purpurata leaf extract (200 mg/kg) orally. Cisplatin (5 mg/kg) intraperitoneal twice per week for two months was given to Group 4 as a standard drug. For two months, Group 5 acquired daily oral A. purpurata leaf extract (200 mg/kg). The rats were euthanized after the experiment under light chloroform anesthesia. Ovary and liver samples were obtained for lipid peroxidation, anti-oxidants, membrane-bound enzymes, tumor indicators, and histological investigation.Results Over a 60-day period, rats were given an ethyl acetate extract of A. purpurata at a dose of 200 mg/kg, which lead to in a substantial (p < 0.05) increase in body protein content, as well as enzyme levels. Furthermore, the use of the ethyl acetate extract significantly (p < 0.05) recovered the altered lipid peroxidation activities in the ovarian tissues of both control and experimental rats to near-normal levels. These data imply that the extract has the capacity to quench free radicals, indicating possible anticancer effects.Conclusion The results suggested that, the ethyl acetate extract of A. purpurata exhibited significant antitumor activity on ovarian cancer bearing rats.
Globally nitrogen deposition decreased net carbon sequestration in terrestrial ecosystems by increasing plant-derived carbon decomposition rather than soil priming effects: A meta-analysis
Authors: Dong Hongxin , Lu Jiayu , Liu Minghui , Tao Lei , Lin Junjie , Li Lu-Jun
Published: October 2023

Aims Plant carbon (C) input and soil priming effects (PEs) together determine the net C sequestration of terrestrial ecosystems. These processes are recognized to be largely influenced by nitrogen (N) availability, the global patterns of N deposition effects on soil net C sequestration and the controlling factors for such effects remain unclear.
Methods In this study, we conducted a meta-analysis of 2205 observations from 56 studies worldwide to explore the effect of mineral N addition on net C sequestration and the associated drivers.
Results The meta-analysis found that although mineral N addition reduced soil PEs, it still decreased soil net C sequestration by increasing plant-derived C decomposition. The decrease of net C sequestration was much greater by urea addition than by ammoniacal and nitrate N addition. In addition, mineral N addition only decreased net C sequestration under pyrolytic C and residue C substrate forms. The higher soil organic C (SOC) and total N (TN) content increased net C sequestration by decreasing soil PEs rather than plant-derived C decomposition. Higher soil clay content reduced net C sequestration by increasing plant-derived C decomposition rather than soil PE. Higher incubation temperature reduced net C sequestration by increasing SOC and plant-derived C decomposition. Longer incubation time increased net C sequestration by reducing the decomposition of SOC and plant-derived C decomposition.
Conclusions These results are beneficial for understanding the response of soil net C sequestration to global N deposition, and could improve the prediction of terrestrial ecosystems C balance under global climate changes.
Effects of aerobic exercise on demyelination and brain morphology in the cuprizone rat model of multiple sclerosis
Authors: abbasi maryam , Arghavanfar Hadis , Hajinasab Sepideh , nooraei aref
Published: October 2023

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) that led to brain atrophy. The purpose of this study was to investigate the effects of pre-and post-conditioning with exercise on demyelination and brain morphology. Thirty male rats were randomly divided into five groups (n = 6 per group), consisting of a healthy control group (Control), an MS group, and three exercise groups: the group that performed the exercise protocol (running on a treadmill 5 days/week for 6 weeks) before the MS induction (EX + MS), the group that performed the exercise protocol during the MS induction (MS + EX), and the group that performed the exercise protocol before and during the MS induction (EX + MS + EX). The expression of Myelin basic protein (MBP), and demyelination in the corpus callosum and the volume, weight, length, width, and height of the brain were measured. The EX + MS + EX showed a significant increase in the expression of MBP compared to other MS groups (**p < 0.01) as well as a significant decrease in the area of demyelination of the corpus callosum compared to MS and MS + EX groups (**p < 0.01). However, there were no significant differences between the MS group and exercised groups for brain morphology. The exercise showed neuroprotective effects, as evidenced by decreased areas of demyelination and improved MBP expression.