bluuebunny/crossref_metadata_2025 huggingface dataset:
Freestanding carbon nanofoam papers with tunable porosity as lithium–sulfur battery cathodes
Authors: Neale Zachary G. , Lefler Matthew J. , Long Jeffrey W. , Rolison Debra R. , Sassin Megan B. , Carter Rachel
Published: August 2023

To reach energy density demands greater than 3 mA h cm−2 for practical applications, the electrode structure of lithium–sulfur batteries must undergo an architectural redesign.
Recent advances in electrochemical functionalization using diazonium salts
Authors: Kher Krishna , Dhaker Mukesh , Baroliya Prabhat Kumar
Published: August 2023

Arenediazonium salts have gained attention in the scientific community due to numerous synthetic applications. Functionalization of arenediazonium salt using electricity offers sustainable, economic, and environmentally friendly chemical transformations for arylation, halogenation and annulation.
Base-catalyzed diastereodivergent thia-Michael addition to chiral β-trifluoromethyl-α,β-unsaturated N-acylated oxazolidin-2-ones
Authors: Racochote Sasirome , Naweephattana Phiphob , Surawatanawong Panida , Kuhakarn Chutima , Leowanawat Pawaret , Reutrakul Vichai , Soorukram Darunee
Published: August 2023

Base-catalyzed diastereodivergent thia-Michael addition to chiral β-trifluoromethyl-α,β-unsaturated N-acylated oxazolidin-2-ones leading to a series of chiral thia-Michael adducts in good yields with high diastereoselectivities is described.
Reversible conformational switching of a photo-responsive ortho-azobenzene/2,6-pyridyldicarboxamide heterofoldamer
Authors: Pike Sarah J. , Telford Richard , Male Louise
Published: August 2023

A versatile and short synthetic route to access a photo-responsive foldamer has been established. The robustness of the reversible conformational switching of the foldamer has been determined using UV/Vis, 1H NMR and circular dichroism spectroscopy.
Production and characterization of lipopeptide biosurfactant from a new strain ofPseudomonas antarctica28E using crude glycerol as a carbon source
Authors: Ciurko Dominika , Chebbi Alif , Kruszelnicki Mateusz , Czapor-Irzabek Hanna , Urbanek Aneta K. , Polowczyk Izabela , Franzetti Andrea , Janek Tomasz
Published: August 2023

Stearin-derived waste glycerol as an economic substrate for biosurfactant production usingPseudomonas antarcticaisolated from the Arctic Archipelago of Svalbard.
Electrocatalytic effect of Co3V2O8 nanospheres loaded on Cu-doped MoS2 nanosheets toward enhanced oxygen reduction reaction
Authors: Moradbeigi Nasrin , Bahari Ali , Ghasemi Shahram
Published: August 2023

Copper doping can promote the catalytic activity of MoS2. Co3V2O8 has promising electrocatalytic applications due to the different oxidation states. The porous Co3V2O8/Cu-MoS2 catalyst, with conductivity, has superior ORR activity compared to Pt/C.
Anomalous diffusion of E. coli under microfluidic confinement and chemical gradient
Authors: Raza Md Ramiz , George Jijo Easo , Kumari Savita , Mitra Mithun K. , Paul Debjani
Published: August 2023

We developed a two-layer microfluidic device to study the motility dynamics of E. coli. We show that both confinement and chemoattractant lead to anomalous diffusion, with power-law distributed run lengths and suppression of large-angle tumbles.
A double-well potential model for glass transition in a glassy hydrogel undergoing bi-stable interactions with water
Authors: Xing Ziyu , Lu Haibao
Published: August 2023

Schematic illustrations of a double-well potential model for glassy hydrogels.
International Sponsored Places: 47th FEBS Congress and 22nd Young Scientists’ Forum 2023
Authors: Ollett Lucy
Published: August 2023

Each year, the Biochemical Society fully sponsors the attendance of two outstanding postgraduate or early career members to attend the Federation of European Biochemical Societies (FEBS) Congress and Young Scientists’ Forum (YSF). With a theme of ‘Together in bioscience for a better future’, the 47th FEBS Congress and 22nd YSF combined research presentations, general talks and practical career exercises to showcase the newest developments in biochemistry, molecular biology and related areas. Providing an incredible opportunity to make connections with European colleagues and discuss research with an international audience, we were delighted to offer International Sponsored Places to Dr Yang Li (University College London, UK) and Dr Ewa Blaszczak (Medical University of Lublin, Poland) in 2023.

Here, Yang and Ewa discuss their experiences at this year’s meetings and highlight the valuable networking and interactions developed as a result of their participation.
Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress
Authors: Grilo Luís F. , Martins João D. , Diniz Mariana S. , Tocantins Carolina , Cavallaro Chiara H. , Baldeiras Inês , Cunha-Oliveira Teresa , Ford Stephen , Nathanielsz Peter W. , Oliveira Paulo J. , Pereira Susana P.
Published: August 2023

Maternal obesity (MO) is rising worldwide, affecting half of all gestations, constituting a possible risk-factor for some pregnancy-associated liver diseases (PALD) and hepatic diseases. PALD occur in approximately 3% of pregnancies and are characterized by maternal hepatic oxidative stress (OS) and mitochondrial dysfunction. Maternal hepatic disease increases maternal and fetal morbidity and mortality. Understanding the role of MO on liver function and pathophysiology could be crucial for better understanding the altered pathways leading to PALD and liver disease, possibly paving the way to prevention and adequate management of disease. We investigated specific hepatic metabolic alterations in mitochondria and oxidative stress during MO at late-gestation.

Maternal hepatic tissue was collected at 90% gestation in Control and MO ewes (fed 150% of recommended nutrition starting 60 days before conception). Maternal hepatic redox state, mitochondrial respiratory chain (MRC), and OS markers were investigated. MO decreased MRC complex-II activity and its subunits SDHA and SDHB protein expression, increased complex-I and complex-IV activities despite reduced complex-IV subunit mtCO1 protein expression, and increased ATP synthase ATP5A subunit. Hepatic MO-metabolic remodeling was characterized by decreased adenine nucleotide translocator 1 and 2 (ANT-1/2) and voltage-dependent anion channel (VDAC) protein expression and protein kinase A (PKA) activity (P<0.01), and augmented NAD+/NADH ratio due to reduced NADH levels (P<0.01). MO showed an altered redox state with increased OS, increased lipid peroxidation (P<0.01), decreased GSH/GSSG ratio (P=0.005), increased superoxide dismutase (P=0.03) and decreased catalase (P=0.03) antioxidant enzymatic activities, lower catalase, glutathione peroxidase (GPX)-4 and glutathione reductase protein expression (P<0.05), and increased GPX-1 abundance (P=0.03). MO-related hepatic changes were more evident in the right lobe, corroborated by the integrative data analysis.

Hepatic tissue from obese pregnant ewes showed alterations in the redox state, consistent with OS and MRC and metabolism remodeling. These are hallmarks of PALD and hepatic disease, supporting MO as a risk-factor and highlighting OS and mitochondrial dysfunction as mechanisms responsible for liver disease predisposition.
Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney
Authors: McArdle Zoe , Singh Reetu R. , Moritz Karen M. , Schreuder Michiel F. , Denton Kate M.
Published: August 2023

A solitary functioning kidney (SFK) from birth predisposes to hypertension and kidney dysfunction, and this may be associated with impaired fluid and sodium homeostasis. Brief and early angiotensin-converting enzyme inhibition (ACEi) in a sheep model of SFK delays onset of kidney dysfunction. We hypothesized that modulation of the renin–angiotensin system via brief postnatal ACEi in SFK would reprogram renal sodium and water handling. Here, blood pressure (BP), kidney haemodynamics and kidney excretory function were examined in response to an isotonic saline load (0.13 ml/kg/min, 180 min) at 20 months of age in SFK (fetal unilateral nephrectomy at 100 days gestation; term 150 days), sham and SFK+ACEi sheep (ACEi in SFK 4–8 weeks of age). Basal BP was higher in SFK than sham (∼13 mmHg), and similar between SFK and SFK+ACEi groups. Saline loading caused a small increase in BP (∼3–4 mmHg) the first 2 h in SFK and sham sheep but not SFK+ACEi sheep. Glomerular filtration rate did not change in response to saline loading. Total sodium excretion was similar between groups. Total urine excretion was similar between SFK and sham animals but was ∼40% less in SFK+ACEi animals compared with SFK animals. In conclusion, the present study indicates that water homeostasis in response to a physiological challenge is attenuated at 20 months of age by brief early life ACEi in SFK. Further studies are required to determine if ACEi in early life in children with SFK could compromise fluid homeostasis later in life.
Barriers to Informational Support for Care Partners of People With Aphasia After Stroke
Authors: Shafer Jennifer S. , Haley Katarina L. , Jacks Adam
Published: August 2023

Background:

Care partners of people with aphasia after stroke need various informational supports, such as aphasia education and resources for psychosocial support. However, informational support may vary across clinicians, and access to these supports remains a persistent unmet need. Using implementation science frameworks can help to assess the gap between what is known about an issue and what is occurring in practice.

Aim:

The aim was to identify barriers to providing informational support for care partners of people with aphasia after stroke.

Method and Procedure:

We performed a secondary analysis of qualitative data collected from two of our previous studies. New themes were identified by comparing feedback from both speech-language pathologists and care partners, and previously assigned codes were interpreted relative to the Knowledge to Action (KTA) framework.

Outcomes and Results:

We identified four implementation themes that were specifically related to the action cycle of the KTA framework: (a) Aphasia rehabilitation tends to exclude care partners, (b) aphasia rehabilitation can be hard to understand, (c) structure is lacking for care partner check-ins, and (d) care partner informational support rarely extends beyond the acute phases of recovery.

Conclusion:

The results suggest that changes are needed at both systemic and care provider levels to ensure that tailored information is provided to care partners of people with aphasia.
Front wheel angle control for steering system of intelligent commercial vehicle based on model predictive control
Authors: Li Yafei , Yang Yiyong
Published: August 2023

Accurate control of front wheel angle is essential in intelligent vehicle electric‐hydraulic power steering (EHPS) system, because it has a significant impact on the safety, comfort, and reliability of vehicle steering. However, the accurate control of front wheel angle is a challenging problem due to the non‐linearity of hydraulic power in steering system and the uncertainty of steering resistance. In this paper, a model predictive control (MPC) method for front wheel angle based on steering resistance estimation is proposed. Firstly, through theoretical analysis and practical experiment of EHPS system model, the relationship between front wheel angle and steering wheel angle and the non‐linear characteristics of hydraulic power are obtained. Secondly, a sliding mode observer is established to estimate the front axle lateral tyre force and steering resistance, which is verified by MATLAB/TruckSim co‐simulation. Then a controller based on the MPC theory is designed and applied to the accurate control unit of front wheel angle in the EHPS system for real‐time control. Finally, the simulation and test platform results show that the control algorithm proposed in this paper can precisely control the vehicle's front wheel turning angle within a certain frequency range.
Using a novel biologging approach to assess how different handling practices influence the post-release behaviour of Northern Pike across a wide range of body sizes
Authors: LaRochelle Luc , Burton Declan , Madden Jamie C. , Danylchuk Sascha Clark , Cooke Steven J. , Danylchuk Andy J
Published: August 2023

There is a growing body of research focused on how angled fish respond to catch-and-release (C&R). However, most of those studies do not span a wide range of body sizes for the targeted species. Physical injury and physiological responses to C&R can be size-dependent, and methods used for landing fish of different sizes vary. As such, studying the response to C&R across a range of fish sizes may help inform best practices that improve outcomes for released fish. Northern Pike (Esox lucius) widely ranges in body size. Anglers may land them by hand, cradle, or net, and they are often released voluntarily or to comply with regulations. We angled 25 Northern Pike (total length 620–1030 mm) from one population and recorded fight, handling, and unhooking times across landing methods (i.e., hand, cradle, net). Prior to release, a pop-off biologging package was temporarily affixed to each fish to monitor locomotor activity, depth, and water temperature during a 12-h period post-release to understand how the interaction of landing method and body size influenced post-release behaviour and short-term fate. Fight and handling time increased with increasing body size. Northern Pike landed with a cradle or net had shorter fight times but longer handling times, compared to fish landed by hand. Post-release locomotor activity was greater for larger fish and those landed with a net. Fish <775mm and landed by hand had greater locomotor activity than fish landed with a net or cradle, while fish >775mm landed by hand had reduced locomotor activity compared to fish landed with a net. There was no post-release mortality observed. Collectively, anglers should use a net for Northern Pike >775 mm to avoid long fight times and reduce post-release exhaustion, but also attempt to reduce the extent of handling associated with fish landed by net.
Vending technologies in improving food services
Authors: Belyaeva Marina , Akimova Natalia , Sokolov Alexander , Ziborov Dmitriy , Burlankov Stepan , Davydov Artem
Published: August 2023

To date, vending machines are widespread. If abroad vending machines are used everywhere to sell a wide variety of goods and even services, then in our country, so far, as a rule, only classic coffee machines and spring machines for issuing snacks attract the attention of buyers. Only in recent years, there has been a trend towards the emergence of atypical vending machines in Russia, such as vending machines for the sale of french fries, coffee shops, dumplings, pizza makers, etc. The article presents the developed vending machine for the preparation and sale of potato balls, the principle of operation of innovative vending, the recipe for potato balls with fillers.
Studying varieties of winter durum wheat in interstation test on economic and valuable features
Authors: Ivanisova Anna , Marchenko Dmitriy , Kostylenko Oksana , Dubinina Olga , Antonenko Lubov
Published: August 2023

The purpose of the research was to identify sources of economically valuable traits of winter durum wheat for their further use in the breeding process. The material for the research was 53 varieties of winter durum wheat of various ecological origins: Federal State Budgetary Scientific Institution, Agrarian Research Center “Donskoy”, Federal State Budgetary Scientific Institution “National Grain Center named after P.P. Lukyanenko”, Federal State Budgetary Scientific Institution “North Caucasian Federal Scientific Agrarian Center” (Russia) and Selective Genetic Institute (Ukraine). High frost resistance characterized the following varieties: Helios (90.9%), Bosphor (91.1%), Lakomka (92.2%), Terra (92.9%), Amazonka (93.0%), Aksinit (94.6 %), Cyprida (95.4%). The sources of early ripeness were varieties: Diona, Krucha, Donskoy yantar, Helios, Continent, etc., heading, which was noted from May 20 to 22; short stems: Kurant (77.4 cm), Diona (83.6 cm), Donskoy yantar (84.2 cm), Aqueduct (84.9 cm), Zhivitsa (84.6 cm), Continent (85.1 cm) , Laska (85.1 cm); coarse grains: Yakhont, Lakomka (40.3 g), Krucha (41.2 g), Belka (41.5 g), Siniora (41.6 g), Odari (43.0 g), Continent (43.2 g ), Bella (44.5 g), Bosphor (45.3 g); high productivity: Amazonka (8.86 t/ha), Yakhont (8.90 t/ha), Lakomka (9.60 t/ha), Donskoy yantar (8.87 t/ha), Krupinka (9.20 t / ha), Belka (9.21 t/ha), Siniora (9.24 t/ha), Gavan (9.28 t/ha), Citrina (9.65 t/ha), etc. Identified genotypes of valuable traits and properties can contribute to the implementation of breeding programs to create varieties of winter durum wheat.
Review and analysis of extrusion technology in the production of feed additives based on probiotic microorganisms
Authors: Rudoy Dmitry , Pakhomov Victor , Babajanyan Arkady , Maltseva Tatiana , Rumyantseva Evgenia , Tatarova Anastasia
Published: August 2023

Ensuring a well-organised and sustainable feed base is the main condition for the development of animal husbandry, increasing its productivity and product quality. To ensure active growth and high productivity, probiotic feed additives are added to the feed, which increase the immune response of the host organism to pathogenic microorganisms, increases the conversion of feed and live weight gain. One of the main processes of feed production is extrusion, which can be cold, warm and hot. The hot extrusion process takes place at a temperature above 130℃ and cannot be used in the production of compound feeds with probiotics that withstand temperatures up to 85℃. During cold extrusion, the temperature reaches no higher than 70℃, which allows the extrusion of mixed feed mass, which contains probiotic feed additives.
Peculiarities of tillage in the conditions of dry farming in the cultivation of soybeans
Authors: Semenikhina Yulia , Kambulov Sergey , Pakhomov Victor
Published: August 2023

Soy is a multipurpose oilseed crop. It is highly nutritious and improves soil fertility. Rainfed agriculture needs to improve crop cultivation technologies and focuses on various methods of soil cultivation that contribute to the formation of an optimal agrophysical structure that contributes to a consistently high soybean yield. Therefore, it is expedient and relevant to study the influence of various methods of tillage on the density and hardness of the soil in two phases of soybean development (beginning of soybean vegetation and before harvesting) with the identification of its yield. The following methods of tillage have been studied: flat-cutting, layer-by-layer, mouldboard and without tillage (direct sowing). The highest soil density in both phases of soybean development on the agrobackground without tillage was 1.34 g/cm3 and 1.27 g/cm3. The decrease in soil density was revealed by 13.43-16.53% with flat-cut tillage; by 6.71-16.53% with layer-by-layer tillage; by 5.22-5.51% during moldboard tillage. The highest soil hardness in both phases of soybean development, 1.15 MPa and 2.65 MPa, was established on the agrobackground without tillage. A decrease in soil hardness by 1.53-1.92 times was revealed during flat-cut processing; 1.77-2.77 times with layer-by-layer processing; in 1.64-2.07 at dump. The highest soybean yield was obtained on the agrobackground with flat-cut tillage – 1.90 t/ha. A decrease in yield was established by 15.82% with the layer-by-layer method, by 3.44% with the moldboard method of tillage, by 7.11% on the agrobackground without tillage.
Evaluating the effectiveness of programs for the agricultural sector support at the regional level
Authors: Medvedeva Lyudmila , Barmuta Karine , Fedoseeva Lyudmila
Published: August 2023

The programs for state support of agricultural sector development are implemented in all regions, but their effectiveness depends on many factors that need to be assessed. Based on the data obtained, the complex policy of sectoral development should be adjusted. In the article, the regional programs for agricultural sector development for a number of periods are explored in detail, and the most promising practices are highlighted. Comparative analysis is conducted for different territories, which helps to build a methodology for evaluating the effectiveness of programs using indicators suitable for conducting regional comparative analysis. The study identifies risks that affect the effectiveness of the program and suggests measures to mitigate them. In conclusion, the algorithm of the comprehensive methodology for assessing the effectiveness of regional programs for agricultural sector support is developed.
Study of a pneumatic separator for grain cleaning
Authors: Begunov M.A. , Koval V.S. , Chernyakov A.V.
Published: August 2023

This article deals with experimental studies of a pneumatic separator with a passive deck. Post-harvest handling of grain is one of the important operations in grain production. Quality cleaning and drying contribute to grain storage without significant losses. The grain litter after the harvest of the combine harvester, which takes place in the shortest possible time, is the most clogged. This causes a problem in terms of cleaning. An important problem is also the physical and obsolescence of the cleaning machines, even though the annual workload is relatively small. This has a significant impact on productivity. Of all those in the agricultural industry, the most commonly used separation of grain from impurities is by aerodynamic properties and separation by size on the sieve. The design of an experimental pneumatic separator with a passive deck was developed. Experimental studies of the pneumatic separator with a passive deck were carried out, based on which plots of the dependences of the completeness of the separation were plotted on the angle of inclination of the flap and the feed of the grain material. The optimal parameters and modes of the grain cleaning machine were determined: the lowest losses of the main crop and the cleaning efficiency are achieved at the flap inclination angle α=0˚.
Technology for cleaning glass substrates in glow discharge plasma for microfluidics applications
Authors: Rabotyazheva D.M.
Published: August 2023

The production of microfluidic chips is increasing every year because the technology using the chip allows you to make an express test to obtain the analysis, as well as economically viable. Often microfluidic chips are based on glass in which the microchannels are formed. Accurate production of a microfluidic device requires careful preparation of the glass substrate to improve adhesion for further application of functional layers. The choice of cleaning mode strongly affects the output product, so a clear understanding of what factors affect the quality of cleaning in HF plasma is needed. Mathematical modeling of dependence between plasma power of the glow discharge, time and gas medium first of all gives understanding which cleaning mode is optimal and which parameter affects stronger very relevant for development of this potentially promising technology of quality products.
Modeling of continuous molding process with elsatic composite working tool
Authors: Semenov I.E. , Lavrinenko V.Yu. , ReznyukV K.D. , Brayko D.A.
Published: August 2023

The paper is about researchof mechanical properties of new composite polyurethane. A comparative analysis of the finite element model of the process of forming a thin-sheet product by composite and monolithic working tools is introduced. According to the simulation results, the technological aspects of the use of the composite are given.
Tensile behavior of a laminated magnesium-aluminum composite with axial elliptical holes
Authors: Gurevich L. M. , Pronichev D. V. , Danenko V. F. , Slautin O. V.
Published: August 2023

A 3D finite element simulation of the behavior of a prismatic sample of a magnesium-aluminum composite material AMg6-AD1-MA2-1 with an elliptical defect in the AD1 layer under axial tension was carried out, its strength and the change in the stress-strain state were determined when the thickness of the AD1 layer varied from 5 to 1, 25 mm. A change in the stress-strain state and strength during perforation transfer to the MA2-1 layer was revealed.
Experimental determination of the adhesive characteristics of the “elementary fiber-epoxy matrix” system
Authors: Borodulin A. S. , Nelyub V. A. , Malysheva G. V. , Bertaeva A. A.
Published: August 2023

The paper considers the method of testing the elementary fiber-polymer matrix system. Results of determining the following adhesive characteristics are provided: apparent and local adhesive strength, start and end in the adhesive destruction of the fiber-matrix joint under study. Basalt fiber and epoxy matrix based on the epoxy resin and amine hardener are considered as the study objects. Influence of the samples geometric characteristics on their adhesive characteristics is established. The paper shows that at the depth of the elementary fiber emersion in the polymer matrix equal to 200 µm, the scatter of all determined adhesive characteristics is significantly reduced.
The Investigation of the effect of laser radiation on the dielectric properties of polymethylmethacrylate
Authors: Torshkhoyeva Z. S. , Kunizhev B. I. , Kharaev А.M.
Published: August 2023

The problem of studying the interaction of laser radiation with polymer materials lies in the study of the effect of intense energy fluxes on matter. The effect of pulsed laser radiation on a high-molecular substance was studied from changes in the electrical parameters of the irradiated materials. Changes in ε’, tg δ depending on the frequency of the external field, the dose of laser irradiation, temperature and time were investigated by a highly sensitive physicochemical method -the method of dielectric losses. This article examined the impact of laser radiation on the dielectric properties of polymethylmethacrylate at frequency of 50 kHz within the temperature interval from 170 to 420 K. The authors showed that the processing of the samples with laser radiation leads to substantial changes in the dielectric constant and tangent of dielectric loss angle.
Modeling of the thermal regime of a mobile electric vehicle charge unit
Authors: Petrov T. I. , Basenko V. R. , Safin A. R. , Tsevtkov A. N.
Published: August 2023

Rechargeable batteries are an important element in mobile electric vehicle charging systems. Batteries have an operating temperature range, and outside of this range the performance will be reduced or the equipment will cease to function. It is problematic to check this situation experimentally due to the number of batteries used (1200 pieces), so it is necessary to simulate the thermal operating conditions beforehand. The simulation has been performed in Comsol and a preliminary confirmation of the operability of the batteries in the mobile electric vehicle charging unit has been obtained.
Biomechanics of sports and technical skill, taking into account causal relationships and the effectiveness of technical actions
Authors: Ivanova Anna , Ryzhkin Nikolay , Savchenko Yulia
Published: August 2023

The article deals with the formation of technical skill with a close relationship of all aspects of an athlete's training, which is a complex dynamic system of conjugated interaction of structures and functions, due to the specifics of the high jump. The main objective of the study was to determine the true cause of the shortcomings in the athlete's movement technique, taking into account the complex causal relationships of factors that determine the high efficiency and stability of technical actions. The study revealed a system of relationships between these factors in high jumps; which is of fundamental importance for building and improving technical skills.
Strategies for assessing the effectiveness of an online education program
Authors: Turdieva R. S. , Razzakova G.R.
Published: August 2023

There are a number of useful approaches that may be used to carry out a more superficial examination of skill progress. Despite the fact that assessment is a huge and rigorous topic of study as well as a possible career opportunity in and of itself, there are a number of these methods. You may want to analyze the degree of skill acquisition where training is the program input, skill attainment is a short-term consequence, and the training receivers are only a transient benefit group. This article investigates the strategies for evaluating online training efficiency by means of Kirkpatrick’s approach. Methods, challenges and techniques are given in more details.
Linguopragmatic characteristics of electronic typing on the basis of business correspondence
Authors: Sayibova Zukhra , Kertayeva Zaure
Published: August 2023

Topicality of the research is conditioned by the followings: 1) that it is done in the framework of modern linguistic trend – Linguopragmatics; 2) by the absence of scientific works devoted to the investigation of Linguopragmatic peculiarities of electronic writing. Aim and tasks of research: to determine the term linguopragmatic , to show that Business correspondence is one of the main writing styles where linguopragmatic categories are used mostly in order to convey the written electronic message successfully and to show the usage of linguopragmatic principles through the analysis .Subject and object of research: object is electronic business correspondence ,subject is linguopragmatic peculiarities of business correspondence Methods of research: descriptive , analytic.The degree of novelty of the research is determined by the fact that this is the first investigation devoted to the linguopragmatic peculiarities of electronic business correcpondence . Practical value and degree of embed: the material of the research can be used in delivering lectures and practical lessons on Linguopragmatics, Text Analysis, Linguopragmatic Studies, in writing research works, text books and manualsThe results obtained: 1) linguistic specificity of concept lingupragmatic has been defined 2) a complex method of linguopragmatic analysis has been worked out; 3) the role of Linguopragmatic categories such as Gricean maxims, Speech act functions , Politeness and explicit way of expressing message in business correspondence been revealed General summary and recommendations.In order to reach the success in conveying message in business correspondence according to the research in analyzed types of business letters Linguopragmatic categories such as Gricean maxims, Speech act functions , Politeness and explicit way of expressing message are applied.
Economic terminology of the Uzbek language: Sources and methods of development
Authors: Asilova G. A. , Shirinova E. T. , Iskandarova G. T.
Published: August 2023

By the authors of the paper analyzing several properties of the economic terminology of the Uzbek language. In particular, data are given on the research of terms in various fields in Uzbek and world linguistics, interpretations of special terms in the works of linguists, and also considers the systemic characteristics, sources and ways of developing the economic terminology of the Uzbek language. Also paid attention to the process of development of the economic terminology of the Uzbek language based on the internal language potential, namely the methods of affixation, composition, abbreviation, semantic and others. Substantiated the role of borrowing in the development of the language in general and in the enrichment of economic terminology in particular. Considered the views of linguists from different countries on this issue. The opinions of the authors are substantiated by examples, which analyzed during the study.
Contemporary linguistics in the light of new paradigms
Authors: Normurodova Nozliya
Published: August 2023

This article presents an analysis for the first time from the standpoint of new directions of linguistics an attempt was made to study comprehensively verbal markers of anthropocentrism in discourse. The aim of the thesis is to identify verbal markers of anthropocentrism in literary discourse, based on semantic-stylistic, communicative-pragmatic, cognitive, cultural, psychological characteristics of the discursive personality of the author and personage. Accordingly, in the article: a new approach has been applıed to the analysis of literary discourse from the standpoint of the methodological principles of anthropocentrism, interdisciplinarity and integrity; the distinctiveness of literary discourse has been defined as one of the most complex types of communication -literary and cognitive, the subjects of which are the author and the personage; the provision on anthropocentrism of literary discourse being manifested in the discursive personality of the author and character was grounded;level parameterization of the linguocreative discursive personality of the author and the character from the standpoint of their semantic-stylistic, communicative-pragmatic, cognitive, cultural, and psychological characteristics has been carried out.
Development of world modern linguistics and discourse interpretation in it
Authors: Raupova Laylo , Khursanov Nurislom , Khursanova Laylo , Polatova Sarvinoz
Published: August 2023

In world linguistics, a number of directions are being formed that research the practical aspect of language. Language owners differ in terms of their past and present, outlook, level, cultural and moral level, ethnic and religious values, lifestyle, development and decline, traditions and spiritual attitudes. At the same time, in linguistics, there is a need for research based on the commonality of language and culture, language and communication, language and psyche, in particular, research that provides a linguistic, cultural, cognitive and lexicographical description of the language. The present paper discusses about the development of world modern linguistics and discourse interpretation in it.
Genetic predictors of interpersonal dependence
Authors: Ermakov Pavel , Kryuchkova Anna , Ryagin Sergey
Published: August 2023

For several decades, numerous scientific discussions about the definition and essence of the codependency phenomenon have been ongoing. At the same time, some researchers note a close relationship between this phenomenon and the concept of interpersonal dependence, considering its destructive and positive impact on personality. The relevance and value of the conducted research lies in the fact that despite numerous studies, including interdisciplinary ones, the question about the nature of interpersonal dependence remains open. The aim is to study the differences in levels of interpersonal dependence in different polymorphic variants of catechol-O-methyltransferase (COMT) and dopamine D2 receptor (DRD2) genes. An interdisciplinary molecular genetic and psychological study of 132 women with drug addiction in remission for more than two years was conducted. As a psychological tool was used, “The Interpersonal Dependency Inventory” developed by R. Hirschfield and adapted by O.P. Makushina was used. For determining the polymorphic variants of candidate genes, a method of isolating genomic DNA from buccal epithelial cells was used. The candidate genes considered were genotypes and alleles of the neurotransmitter pathways COMT and DRD2. For statistical processing of the obtained data, the nonparametric Mann-Whitney U-test was used. Substantial differences were found between the levels of interpersonal dependence in the genotypes VV and VM of the catechol-O-methyltransferase (COMT) enzyme; a trend of statistically significant differences was detected between the levels of interpersonal dependence in the genotypes CT and TT of the DRD2 gene. The features identified during the study should be taken into account in the process of carrying out psychological and preventive measures for people with addictive behaviour.
Influence of the parameters to transition capacitance at nCdS-pSi heterostructure
Authors: Sapaev I. B. , Sapaev B. , Sadullaev S. , Abdullayev J. Sh. , Umarov A. V. , Siddikov R. U. , Mamasoliev A. A. , Daliev K. S.
Published: August 2023

It is important to research the dependence of the capacitance and capacitance on the parameters on the photodiodes. In this article, we aim research experimental and theoretical on the nCdSpSi heterostructure. A heavily doped n+CdS layer with a thickness of about 50 Å was created by deposition of a thin layer of indium (In) for 25-30 s on the surface of a CdS film in vacuum with a residual pressure of 10-5 Torr at a substrate temperature of 373 K, followed by annealing at 673 K in within 300s. Then, on the surface of this heavily doped n+CdS layer, a current-collecting “P”-shaped ohmic contact with an area of 3 mm2 was obtained also by the vacuum evaporation of In.
Development of multicomponent hybrid powders based on titanium and niobium carbides as a promising material for laser cladding
Authors: Okulov A. V. , Iusupova O. S. , Liu Kun
Published: August 2023

Multicomponent hybrid TiC-NbC(Zr, Si) powder was developed and manufactured by mechanosynthesis in a high-energy vibratory ball mill. High-purity fragmented TiC, NbC, Zr and Si powders were selected and mixed in a ratio of 60:15:10:15 at.%, respectively, to manufacture the above powder. Several modes of mechanosynthesis were chosen for the experiment: 3, 6, 9 and 12 hours. Scanning electron microscopy (SEM) and X-Ray diffraction (XRD) analyzes were used to study the morphology, chemical and phase compositions of the obtained TiC-NbC(Zr, Si) powder. The SEM analysis confirmed the presence of all TiC, NbC, Zr and Si components in the final powder regardless of the mechanosynthesis time. However, the XRD analysis showed that after 9 and 12 hours of mechanosynthesis, the Zr and Si diffraction lines are completely absent. This occurs due to the dissolution of the Zr and Si elements in titanium and niobium carbides. In addition, it has been established that more than 6 hours are required to synthesize finely dispersed TiC-NbC(Zr, Si) powder. The study results can be useful for optimization of the mechanosynthesis process.
Scientific basis for the development of structural and technological devices made of modern domestic materials to ensure the functional reliability and safe operation of surface water intakes
Authors: Khetsuriani Jelguja , Kokhanov Yuriy , Tkacheva Irina , Neidorf Anna , Bekbergenova Victoria
Published: August 2023

The article provides a classification list of a large number of heuristic techniques for solving various problems of designing a class of hydraulic structures, taking into account the conditions of functional operation of soft floating structures (MNCs) as water intake structures. The concept of rational use of surface water resources provides for an ecosystem approach that allows us to consider a water body together with the catchment area of the hydrographic river network, the surface layers of the atmosphere above it, measures taken to select the calculated water flow rate (Q m3/s), taking into account the consideration of environmental safety in the zones of influence of water intake - as a single system in as a whole. Providing EC in VTK puts forward a number of main tasks to improve existing structural and technological devices and create new ones using modern domestic materials, for example, high-strength synthetic fabric materials. When creating environmentally acceptable design solutions to provide EC in the zones of influence of VTK, one of the most promising areas at present is the methodological basis for the synthesis of soft-coated structures in the composition of VTK. The reliable functioning of both a separate structural element and the structure as a whole should be conditioned by the possibility of periodic updating of its constituent structural elements.
Development of nanocomposite materials for road construction
Authors: Tarasova Marina , Trotsenko Irina , Korchevskaya Julia , Chemisenko Oleg
Published: August 2023

The level of economic development of any state can be determined today by the quality of roads. Consequently, a wide variety of projects and concepts have appeared in almost many countries recently, which radically change the idea of roads. Reliability and safety of delivery of various cargoes largely depends on the quality of construction and repair of modern road surfaces. Road works related to their various types (replacement of the canvas, marking) cannot be carried out without additional signs and fencing devices. This article discusses the possibility of replacing the polymer matrix that forms the basis of fencing devices (plastic cones, road barriers) with polytetrafluoroethylene (PTFE) using a reflective component. As a reflective component, it is proposed to use a photoluminophore, which is capable of converting absorbed energy into light radiation, providing continuous light emission for 10 hours. The main criterion of this material is its light output in the dark.
Application of the project method using modern IT technologies
Authors: Kovalchuk N. V. , Timashova M. V. , Shcherbakova I. V.
Published: August 2023

This article is devoted to the application of project methodology using IT technologies in the process of studying the subject “Foreign language” and “Foreign language in professional sphere” in the conditions of professional education among students of non-language high school. The article also analyzes the project methodology used as one of the best methods of teaching a foreign language. The article deals with the main theoretical and practical foundations of using project methodology in the educational process. Particular attention is paid to the consideration of the working phases of the project, as well as shown methodological techniques used by the teacher at different stages of the project. Besides, the article has covered the results of the experiment held by the “Foreign language in the sphere of Engineering and Technologies” department among the students of the Faculty of Industrial and Civil Engineering of the Don State Technical University, in connection with which the conclusion is made that the project method application has a considerable influence on the increase of the level of motivation of students to learn a foreign language and the effectiveness of teaching.
Approximation model based on LSTM for predicting the next prime number in an infinite sequence
Authors: Pylov Petr , Maitak Roman , Protodyakonov Andrey
Published: August 2023

Prime numbers are a special set of natural numbers that have captured the attention of mathematicians since ancient times. As prime numbers are a fundamental component in many areas of mathematics, they have naturally found wide applications in various fields of knowledge, such as cryptography. The goal of all researchers is to discover the distributional relationships within this infinite set of numbers or, at the very least, to create a mathematical model for predicting the next prime number in a diverging sequence. This article is dedicated to an attempt at solving this problem based on a deep learning model -Long Short-Term Memory (LSTM) neural network.
How Effective Are Cardiopulmonary Bypass Circuits at Removing Gaseous Microemboli?
Authors: Jones Timothy J. , Deal Dwight D. , Vernon Jason C. , Blackburn Noel , Stump David A.
Published: August 2023

An association has been demonstrated between intravascular microemboli and organ injury during cardiopulmonary bypass (CPB). Air may be inadvertently introduced into the venous line during CPB resulting in the formation of gaseous microemboli (GME). We studied the ability of CPB circuits, from five different manufacturers, to remove GME originating from the introduction of air into the venous line. Using an in vitro model of adult CPB, 60 ml of air was introduced into the venous line and the progression of GME through the circuit components was monitored at 5 locations. In all circuits GME were detected in the arterial line following the introduction of air into the venous line. There was a wide variation between manufacturers in the ability of the circuit to remove GME. Air introduced into the venous line during CPB results in the formation of GME that are able to pass through all the circuit components including the arterial filter. The quantity of GME detected in the arterial line is influenced by the design of the circuit components and varies between manufacturers. Air in the venous line should be avoided and if present it must be dealt with promptly.
Expanding Perfusion Services Through Mobile Point-of-Care Coagulation Monitoring
Authors: Kohtz Ryan J. , Stammers Alfred H. , Mills Nancy J. , Petterson Craig M. , Nichols Jeffery D. , Kmiecik Scott A. , Liu Jun-Li , Zheng Hong
Published: August 2023

Current trends in cardiac surgery have challenged perfusionists to seek diversification of services. Point-of-care coagulation (POCC) monitoring represents a desirable area of perfusion service expansion. The purpose of the study was to create a series of hemostatic conditions to assess the functionality of POCC monitors to identify specific coagulopathies with identifiable profiles for algorithm development.

Fresh (<4 h) bovine blood, anticoagulated with anticoagulant citrate dextrose, was adjusted to a hematocrit of 30.0 ± 2.0%. Hypofibrinogenemia (≤90 mg/dL), thrombocytopenia (≤70,000/ mm3), platelet dysfunction (850 µg/mL of nitroglycerin/mL of blood) and hyperfibrinolysis (0.40 units of urokinase/mL of blood) were created. Five POCC devices were used to evaluate activated clotting time, thrombin time, fibrinogen, platelet function, prothrombin time, activated partial thromboplastin time and thromboelastograph. Results are reported as percentage change from control for each test (abtract table). Each test performed showed specificity and sensitivity for certain coagulopathies, however variability amongst monitors was encountered. In conclusion, the development of a mobile cart incorporating POCC monitors with knowledge of specific coagulopathic conditions may expand perfusion service.

Summary of results for induced coagulopathesis.

Device
Hypofibrinogenemia
Thrombocytopenia
Platelet Dysfunction
Hyperfibrinolysis

TEG index
−146% p < .05
−84% p < .05
−415% p < .05
−90% p < .05

ACT
23% p < .05
4% p = NS
89% p < .05
27% p < .05

Thrombin time
16% p = NS
−4% p = NS
19% p = NS
20% p = NS

Fibrinogen
–47% p < .05
−19% p = <.05
12% p = NS
5% p = NS

Platelet function
No result
−43% p < NS
No result
−19% p = NS
The Effects of Ultrafiltration on e-Aminocaproic Acid: An In Vitro Analysis
Authors: Petterson Craig M. , Stammers Alfred H. , Kohtz Ryan J. , Kmiecik Scott A. , Nichols Jeffrey D. , Mills Nancy J. , Liu Jun-Li
Published: August 2023

Blood conservation strategies have become a standard of practice in cardiac surgery, with the use of antifibrinolytic agents and ultrafiltration two popular techniques. The purpose of this study was to evaluate the effects of continuous ultrafiltration on e-aminocaproic acid (EACA) utilizing functional coagulation analysis. A fibrinolytic assay was developed to detect EACA using the thromboelastograph (TEG) and urokinase (0.138 units 0.360 mL−1). Fresh bovine blood (23 ± 1% hematocrit) was pumped (100 mL min−1) through an ultrafiltrator (HPH 400) at 37°C with a transmembrane pressure of 280 mmHg. EACA (0.065 mg mL−1) was circulated for 10 minutes before initiating ultrafiltration. Samples (pre- and postultrafiltrator) were obtained at baseline, 5, and 10 min of ultrafiltration and analyzed via the fibrinolytic assay for EACA determination. TEG profiles significantly decreased from concentrations of 0.065 mg to 0.0325 mg of EACA mL−1 blood (maximum amplitude MA, 75.4 ± 4.0 versus 63.3 ± 2.9, p < .05, TEG index 5.4 ± 0.7 versus 4.0 ± 0.3, p < .05). Fibrinolysis at 30 min increased as EACA concentrations declined (0.065 mg, 0% versus 0.032 mg, 16.4 ± 2.8%, p < .05). During ultrafiltration the MA increased significantly from baseline to 10 min postultrafiltrator (68.2 ± 3.0 versus 75.8 ± 10.0, p < .05) and from 5 min pre- to 10 min postultrafiltrator (69.7 ± 4.2 versus 75.8 ± 10.0, p < .05). The TEG index showed no significant change, and no fibrinolysis was detected at 30 min from any datapoint during ultrafiltration. In conclusion, this study demonstrates that the antifibrinolytic properties of EACA are maintained during ultrafiltration with a 25% reduction in total circulating volume.