Quality of life indicators in women with chronic coronary heart disease with comorbid association with metabolic syndrome
Authors:   Research Institute of medical problems of the North – a separate division of «Federal Research Center «Krasnoyarsk Scientific Center» Siberian Branch of the Russian Academy of Sciences», Krasnoyarsk, Russia, Moskalenko Oga L. , Yaskevich Roman A. ,   Research Institute of medical problems of the North – a separate division of «Federal Research Center «Krasnoyarsk Scientific Center» Siberian Branch of the Russian Academy of Sciences», Krasnoyarsk, Russia; Professor V.F. Voino-Yasenetsky Krasnoyarsk Sta, Davydov Evgeny L. ,   Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia
Published: February 2025

The leading position in the structure of causes of death from cardiovascular diseases is occupied by coronary heart disease, which is the most serious problem of modern cardiology and medicine in general. Patients with coronary heart disease have significant physical and mental problems, as well as a deterioration in health-related quality of life indicators. The decrease in quality of life in patients with coronary heart disease may be due to the course of the underlying cardiovascular and comorbid pathology. According to previous studies, patients with coronary heart disease who had adverse metabolic risk factors such as diabetes mellitus, obesity and central obesity also had low quality of life scores.
The purpose. To study the indicators of quality of life and factors influencing its decrease in women with chronic coronary heart disease with comorbid association with metabolic syndrome.
Materials and methods. 160 women with chronic ischemic heart disease were examined, of which 130 had metabolic syndrome. Metabolic syndrome was diagnosed based on the criteria of clinical recommendations of the All-Russian Scientific Society of Cardiology in 2009. The quality of life and the degree of its decline were determined using the methodology developed by A.G. Gladkov et al. (1982) adapted by T.A. Ayvazyan et al. (1989).
Results. Among the examined women with chronic coronary heart disease who have metabolic syndrome, indicators of quality of life of varying degrees of decrease were found in more than 80% of the surveyed, among whom a significant decrease in quality of life was detected in 36,7% of cases. A marked decrease in quality of life in women with chronic coronary heart disease who have metabolic syndrome was more often observed in people with a five-component combination of metabolic syndrome. The most frequent clusters of metabolic syndromes among women with different levels of quality of life reduction were three- and four-component combinations, including abdominal obesity, arterial hypertension and dyslipidemia disorders. More often, the decrease in quality of life in women with chronic coronary heart disease who have metabolic syndrome was influenced by such reasons as a decrease in activity in daily life, a change in relationships with colleagues, demotion and the need for treatment.
Conclusion. It was found that in women with chronic coronary heart disease, the decrease in quality of life was largely due to the presence of the metabolic syndrome.