bluuebunny/crossref_metadata_2025 huggingface dataset:
Immediate and longer-term impacts of fetal surveillance education on workforce knowledge and cognitive skills
Authors: Beaves Mark , Zoanetti Nathan , Wallace Euan M , Palmer Kirsten R
Published: July 2023

Background: Following the development of the Royal Australian College of Obstetricians and Gynaecologists Intrapartum Fetal Surveillance Guideline in 2003, an education program was developed to support guideline implementation and clinical practice. It was intended that improved clinician knowledge, particularly of cardiotocography, would reduce rates of intrapartum fetal morbidity and mortality. The program contains a multiple-choice assessment, designed to assess fetal surveillance knowledge and the application of that knowledge. We used the results of this assessment over time to evaluate the impact of the education program on clinicians’ fetal surveillance knowledge and interpretive skills, in the immediate and longer-term.

Methods: We undertook a retrospective analysis of the assessment results for all participants in the Fetal Surveillance Education Program, between 2004 and 2018. Classical Test Theory and Rasch Item Response Theory analysis were used to evaluate the statistical reliability and quality of the assessment, and the measurement invariance or stability of the assessments over time. Clinicians’ assessment scores were then reviewed by craft group and previous exposure to the program.

Results: The results from 64,430, broadly similar assessments, showed that participation in the education program was associated with an immediate improvement in clinician performance in the assessment. Performance improvement was sustained for up to 18 months following participation in the program and recurrent participation was associated with progressive improvements. These trends were observed for all craft groups (consultant obstetricians, doctors in training, general practitioners, midwives, student midwives).

Conclusions: These findings suggest that the Fetal Surveillance Education Program has improved clinician knowledge and the associated cognitive skills over time. The stable difficulty of the assessment tool means any improvement in clinician’s results, with ongoing exposure to the program, can be reliably assessed and demonstrated. Importantly this holds true for all craft groups involved in intrapartum care and the interpretation of cardiotocography.
What women should know about emergency contraception - analysis of women's awareness and experiences after its use
Authors: Śnieżek Kinga , Dobko Katarzyna , Frącz Gabriela , Glac Agata , Kuliga Klaudia , Musz Kinga , Sejnowska Natalia , Socha Agnieszka , Surowiec Agata , Zając Anna
Published: July 2023

Introduction: Emergency contraception is a method of contraception instigated when the other ones have failed or after unprotected sex. Although highly effective, it is subject to the risk of side effects.
Aim of the study: The purpose was to assess the women's knowledge regarding emergency contraception methods and to analyze the experience related to the use of levonorgestrel and ulipristal acetate.
Materials and methods: The research was done by conducting an anonymous online survey. The study took place in May 2023 and included 214 women over 15 years of age. The results were analyzed in Excel with a consideration of scientific literature.
Results: 64.5% of women indicated correctly what emergency contraception is, 13.1% misunderstood its definition. 86% of respondents were unaware that the emergency contraception could be used for up to 120 hours after sex. 45% of women who used emergency contraception had difficulties obtaining a prescription. 35% of those surveyed indicated that they had side effects, the two most commonly reported being nausea and fatigue.
Conclusions: Most women know the definition of emergency contraception, however, the vast majority of the respondents failed to specify how soon the emergency contraception shall be implemented after the intercourse. A large percentage of women reported difficulties in obtaining a prescription for emergency hormonal contraceptives. Therefore, the society should be better educated when it comes to emergency contraception and further actions should be implemented to improve its availability.
Diversity of woody plant nematodes in specially protected biocenosis of Zarafshan Mountain, Uzbekistan
Authors: NARZULLAYEV SARDORBEK , KAMBAROV SARDOR , MIRZAEV UKTAM , TURSUNOVA SHAHLO
Published: July 2023

Abstract. Narzullayev S, Kambarov S, Mirzaev U, Tursunova S. 2023. Diversity of woody plant nematodes in specially protected biocenosis of Zarafshan Mountain, Uzbekistan. Biodiversitas 24: 3145-3151. Very little information exists on nematodes' diversity and ecological characteristics in small artificial forests. This article provides information on the diversity of the nematode fauna, bioecological characteristics, and species distribution by biotopes of fruit trees growing in the biocenoses of the Omonkutan National Nature Park in the Western Zarafshan mountain range. As a result of the research, 62 species of nematodes were recorded in the nematode fauna of fruit trees. These species were analyzed taxonomically and ecologically. It was determined that the species in the fauna belong to two classes and five orders of the Nematoda type. They are divided into five large and several small groups according to their ecological characteristics. Among the ecological groups, omnivorous and plant-feeding nematodes are the dominant groups in terms of the number of species. The diversity of nematodes was high in the 0-15 and 15-30 cm soil layers. It turned out that the diversity in different biotopes is related to the ecological characteristics of nematodes. In particular, herbivorous nematodes accounted for 72.2% of nematodes in the root system. An increase in the diversity of nematodes was observed in the rhizosphere soil layers. A sharp increase in the number of species and individuals of omnivorous nematodes and bacteriotrophs was observed in the 0-15 cm soil layer, and this trend was also preserved in the 15-30 cm layer. The species richness and diversity (according to the Shannon and Simpson indices) were the lowest in vegetative parts of plants. As a result of the research, it became clear that the diversity of soil nematodes is completely dependent on their trophic characteristics.
Ecological niche affects mitochondrial DNA diversity and variation in near-threatened Himalayan vulture (Gyps himalayensis)
Authors: Ummee Chanatip , Sitdhibutr Ratiwan , Lertwatcharasarakul Preeda , Kasorndorkbua Chaiyan
Published: July 2023

Abstract. Ummee C, Sitdhibutr R, Lertwatcharasarakul P, Kasorndorkbua C. 2023. Ecological niche affects mitochondrial DNA diversity and variation in near-threatened Himalayan vulture (Gyps himalayensis). Biodiversitas 24: 3630-3640. The impact from the use of diclofenac on the Indian subcontinent is the main reason why the Himalayan vulture Gyps himalayensis Hume, 1869 has near-threatened conservation status. In particular, it has ecological niches different from those of other vultures in the same genus; however, there has been no systematic study on genetic diversity. This study analyzed the genetic diversity of Himalayan vultures that had migrated to Thailand during the winter in conjunction with samples from a limited GenBank database. The results identified no evidence of Himalayan vulture genetic diversity loss after Gyps vultures were affected by diclofenac since the 1990s and the values were related to raptors with stable population status, which may be the result of ecological niche. Genetic differences or group divided were found in the mitochondrial DNA (mtDNA) Control Region (CR) and Cyt b+CR except in Cytochrome b (Cyt b). The group division based on the results of genetic distance between CR and Cyt b+CR shows that the genetic distance between groups of CR was 10-12 times greater than that of Cyt b (0.771±0.055-0.923±0.084 and 0.076±0.068, respectively) and the difference was also present when analyzed with the combined data set of Cyt b+CR (0.448±0.036). This is an important indicator for the possible study of population structure through phylogeography, because the Cyt b from other studies did not indicate any genetic differences between populations of Himalayan vulture and other Gyps vultures, which may update conservation proposals to be more accurate and effective.
Navigating boundaries in coproduced research: a situational analysis of researchers’ experiences within integrated knowledge translation projects
Authors: Ackerley Chris , Balka Ellen
Published: July 2023

Background:

Research coproduction is advocated as an approach to produce more impactful evidence, by valuing a diversity of expertise and integrating knowledge users into research processes. Yet, extant literature finds that trying to bridge boundaries between different types of knowledge can also cause collaboration challenges and present barriers to success in coproduction.

Aims and objectives:

To study how researchers understand and manage knowledge boundaries in coproduced health research, or ‘integrated knowledge translation’ (IKT) as it is referred to in Canada.

Methods:

Data were collected from: 1) semi-structured interviews (n=20) with researchers leading different IKT projects across Canada; and 2) participant observation and document analysis for an in-depth case study of one IKT project. Data were combined and analysed using situational analysis, a modified grounded theory approach to visually map patterns of discourse along salient axes of controversy.

Findings:

We describe four key discursive positions participants take concerning knowledge boundaries in IKT: to recognise and handle, respect and clarify, blur and integrate, or challenge and embrace. These are plotted relative to two salient axes: the degree to which participants viewed boundaries as a problem, and the degree to which they believed boundaries should (or could) be challenged.

Discussion and conclusion:

The four discursive positions identified will help those doing coproduced research to critically reflect on their own position(s) regarding boundaries in collaborative research, and strategically discuss, select, or switch discourses as needed to support their goals.
Instruments of Power. The affective power of sound design in American music education
Authors: Karvelis Noah , Popkewitz Thomas S.
Published: July 2023

Music education in the United States has increasingly focused upon student creativity and practices such as improvisation. While such practices and changes are often conceptualized as flexible, inclusive reforms about making kinds of children, historically the curriculum has little to do with music and is instead concerned with taming uncertainty in the governing of child.   We examine the Orff-Schulwerk pedagogy in the teaching of music, thought of as a progressive reform which emphasized improvisation and creativity. Exploring briefly Orff-Schulwerk’s production in the Weimar Republic as it travels and translated into the post-war United States, we consider the curriculum as formed through psychological research about rationality, choice, and creativity. The focus is on the system of reasoning embodied in the curriculum as generating principles about desired kind of persons in a stable, secure future related to salvation narratives- principles different in the Weimar Republic and US. The shifting design of people in Orff-Schulwerk curriculum and classroom instruments for learning of sound are, we argue, practices in governing of the body and soul. The fabricating and mapping in the music curriculum is about kinds of populations required as evidence of the progressive desires that simultaneously distributes differences.
Od metropolii podzielonej do metropolii zjednoczonej – kształtowanie się tożsamości instytucji metropolitalnego zarządzania w kontekście relacji miast górnośląskiego obszaru metropolitalnego
Authors: Neuve-Église Zuzanna
Published: July 2023

The Upper Silesian conurbation is a unique area in Poland due to its polycentric nature, expressed in the interaction of a group of cities. The paper describes the transformation of the image of the “metropolis” in the Silesian Voivodeship, addressing the issues of complex relations between the cities of the Upper Silesian Metropolitan Area. The results of the qualitative content analysis of strategic programs of the municipalities participating in the metropolitan union since 2017 highlighted two main categories of the concept of “metropolis” – a chance and a threat. Then, the selected aspects shaping the identity of the institution of metropolitan management were demonstrated based on the regional press discourse analysis. Thus, this paper explores a path of metropolitan integration of the municipalities in the face of the emergence of a new metropolitan institution – from rivalry tendencies based on the historical and cultural divisions of the region and the revival of local identities to conciliatory attitudes.
Being and the Philosopher’s Object in Plato’s Sophist
Authors: Granieri Roberto
Published: July 2023

In the Sophist, Plato claims that the philosopher is always engaged through reasonings with the idea tou ontos (254a4–b1). I argue that, contrary to appearances and to what various commentators believe, this phrase does not refer to the Kind Being singled out in the Sophist as one of the so-called ‘greatest’ or ‘most important’ Kinds, but to the whole intelligible realm. The proposed reading better accounts for Plato’s exact wording at Sophist 254a4–b1 and preserves the consistency of Plato’s view on the object of philosophical knowledge. I conclude with some broader considerations on the relationship between this passage, Platonic dialectic and Aristotle’s conception of a science of being qua being.
Hamburger Schulen im "Dritten Reich"
Authors: Schmidt Uwe , Hering Rainer
Published: July 2023

Das vorliegende Buch des Hamburger Pädagogen und Historikers Uwe Schmidt über Hamburger Schulen im „Dritten Reich“ ist die erste Gesamtdarstellung des Schulwesens in der Hansestadt zwischen 1933 und 1945. Sie basiert auf intensiver Quellenforschung. Die umfangreiche Studie umfasst alle Schulformen und geht zudem über die Grenzen der Hansestadt vor 1937 hinaus: Sie arbeitet erstmals die Schulgeschichte der 1937 durch das Groß-Hamburg-Gesetz dazugekommenen, vormals preußischen Städte Altona, Harburg und Wandsbek sowie weiterer Umlandgemeinden auf. Besonders verdienstvoll sind über den inhaltlichen Ertrag dieser Monographie hinaus das qualifizierte Personenregister mit Biogrammen und vor allem die mit großem Aufwand erstellte Übersicht über die einzelnen Hamburger Schulen und ihre Geschichte, wodurch diese Untersuchung auch zum nützlichen Nachschlagewerk wird. Das Werk ist in zwei Teile gegliedert: Band 1 enthält ausschließlich die umfassende inhaltliche Darstellung, während sich in Band 2 eine Listung der Abkürzungen, das Verzeichnis der Schulen von 1933 bis 1945, statistische Aufstellungen, Quellenhinweise, Quellen- und Literaturverzeichnis, die Register (Personen-, Sach- und Geographisches Register), das Abbildungsverzeichnis sowie Informationen zu Autor und Herausgeber, zur Reihe sowie zum Verein für Hamburgische Geschichte finden.
Ritka vércsoport specifikus autoantitest szolid tumoros betegben: auto-anti-N, a direkt Coombs-teszt értelmezése
Authors: Csernus Zita , Cserne Molnár Kinga , Biró Katalin , Scheibl Éva , Dezsőné Siba Krisztina
Published: July 2023

A vércsoport-szerológiai kompatibilitási vizsgálatsor egyik kötelező eleme a direkt Coombs-teszt, mely a vörösvérsejtek antitesttel vagy komplementtel való fedettségét vizsgálja. A teszt pozitív eredménye sok kérdést vet fel a diagnózis megállapításakor, és útmutató lehet a megfelelő terápia kiválasztásához. A vörösvérsejteken lévő autoantitestek ritkán vércsoport-specifikusak, melyek az ABO vércsoportvizsgálatot is befolyásolhatják, továbbá transzfúziós javaslatnál történő figyelembevételük a beadott vörösvérsejtek hosszabb túlélését biztosíthatják.

Több esetben közöltek szolid tumoros betegekben is vörösvérsejt-ellenes, főleg pánreaktív autoantitest-képződést és immunhemolízist. A bemutatott esetünkben ritka IgG auto-anti-N antitest volt azonosítható még nem diagnosztizált vesetumoros beteg szerológiai vizsgálata során, melyet a standard kompatibilitási vizsgálatokon (ABO, RhD, indirekt és direkt Coombs) felül elúciós vizsgálat igazolt ABO vércsoport diszkrepanciával.

A beteg laboratóriumi leletei nem igazoltak hemolízist, hidegagglutinin vizsgálata felvételkor negatív volt. Műtéthez ABO, RhD, Kell és N negatív választott vért adtunk, a transzfúzió eseménytelenül zajlott. Az M, N, S és s antigének az MNS vércsoportrendszer transzfúziós szempontból legfontosabb tagjai. A rendszer antigénjei a vörösvérsejt membrán glikoforinok (GYP) szialoglikoproteinjei. Kódoló génjei a GYPA, GYPB és GYPE. A vörösvérsejt membrán glikoforinok citokinek, baktériumok és vírusok receptorai lehetnek. Az MNS antigének a vese endotéliumon és epitéliumon is jelen vannak. Ismert az N antigén és prekurzorainak carcinoma asszociációja.

A rendszer alloantitestjei általában hidegben reagáló, transzfúziós szempontból általában nem veszélyes IgM típusú természetes antitestek. A ritkán előforduló IgG antitestek azonban hemolitikus transzfúziós reakciót, újszülöttkori hemolitikus betegséget és autoimmun hemolitikus anémiát okozhatnak.

Esetünkkel szeretnénk felhívni a figyelmet a vércsoport-diszkrepancia és a bemutatott ritka autoantitest diagnosztikus értékére, a direkt Coombs-teszt helyes értelmezésének fontosságára, továbbá a szerológiai vizsgálatok körültekintő elvégzésének és értékelésének jelentőségére.
Krónikus myeloid leukémia: Múlt, jelen, jövő
Authors: Batár Péter
Published: July 2023

A krónikus myeloid leukémia ritka betegség, incidenciája 1-2/100 000 eset évente. A myeloproliferatív neopláziák családjának tagja és az egyik legrégebben és legrészletesebben tanulmányozott leukémia. Alapvető cytogenetikai jellegzetessége a 9-es és a 22-es kromoszómák hosszú karja közötti reciprok transzlokáció következtében létrejövő kisebb kromoszóma, melyet az eltérést elsőként leíró kutatók egyetemének székhelyéről Philadelphia-kromoszómának neveztek el. A transzlokáció kapcsán kialakuló fúziós génszakasz egy kóros tirozin-kináz aktivitású fehérjét kódol, amely a myeloid sejtsor osztódásának, differenciálódásának és a programozott sejthalál (apoptózis) jelátviteli szabályozó mechanizmusainak zavarát okozva alakítja ki a betegségre jellemző klinikai képet. Szemben a szolid tumorok és egyéb leukémiák kialakulásának összetett genetikai hátterével, a krónikus myeloid leukémia az egyik ritka példája a korai genetikai kutatások során megszületett egy gén, egy betegség teóriának. Az egyetlen génhiba által vezérelt betegség hatékony kezelése a célzott terápiák sikeres kifejlesztésével egyértelműen igazolta az elképzelés jogosságát. Az egykor gyógyíthatatlan betegség az elmúlt két évtizedben a célzott kezelési módszerek rendkívüli sikerének köszönhetően mára az esetek nagy részében a tirozin-kináz-gátló terápiával gyógyítható betegséggé vált. A nemkívánatos mellékhatások és a tirozin-kináz-gátló kezeléssel szemben rezisztens esetek azonban továbbra is jelentős kihívást jelentenek. Folyamatos és intenzív kutatások folynak mind a diagnosztika fejlesztésére, mind pedig az újabb típusú kezelések hatékonyabb célpontjainak megtervezésére és vizsgálatára.
Batallas por la legitimidad política. El Perú del libertador José de San Martín y los discursos políticos en conflicto en América del Sur
Authors: Morán Ramos Luis Daniel , Carcelén Reluz Carlos Guillermo
Published: July 2023

En el contexto de los bicentenarios de las independencias en América Latina el estudio de la historia política y cultural ha significado una renovación historiográfica importante. En esa perspectiva, el análisis de los discursos políticos de la prensa de Lima, Buenos Aires y Santiago de Chile nos permiten advertir un complejo conflicto de intereses por la legitimidad política en aquella coyuntura revolucionaria que pone en evidencia las diversas maneras y las motivaciones disimiles que los actores sociales tuvieron que enfrentar en el teatro de la lucha militar y la guerra por la opinión pública. En ese sentido, esta investigación desarrolla aquellos discursos políticos divergentes que devienen en una guerra de propaganda de escala continental con epicentros en estas capitales en tiempos del protectorado del general José de San Martín en el Perú.
Reserves for reducing energy consumption when rolling section bars on modern rolling mills
Authors: Fastуkovskii A. R. , Glukhov M. I. , Vakhrolomeev V. A.
Published: July 2023

Metallurgical production is a highly energy-intensive process, and the search for solutions to reduce energy costs remains an urgent task for all stages. In this regard, the production of finished rolled products is considered as the most promising direction for the implementation of energy-saving technologies. There are two ways to reduce energy costs in hot rolling of section bars: saving energy for heating and improving the use of the main equipment to reduce intermediate energy costs. Due to the difference in silt conditions at the moment of capture and at the steady stage of the rolling process, a reserve of retracting friction forces arises, which can be used for additional shaping in non-drive devices and thereby increase the efficiency of the main equipment and reduce overall energy costs. For the practical implementation of the proposed concept, dependence was obtained that makes it possible to estimate the power potential that is not used at the steady stage of the rolling process. Using the obtained dependence, it was found that when rolling in smooth rolls, the potential of friction forces is used only by 50 – 60 %, and when rolling in calibers, by 35 – 40 %. It was experimentally established that during the rolling of shaped sections in passes with an elongation ratio of less than 1.10 – 1.15, more than 50 % of the energy is spent on idling. However, by replacing drive stands in these passes with non-drive cassettes (in continuous groups), it is possible to increase the efficiency of adjacent stands by 4 – 5 % and reduce energy costs.
İktisadın Diğer Bilimlerle İlişkisi: İktisat Eğitiminde Dönüşüm
Authors: UMUTLU Hasan , MEÇİK Oytun
Published: July 2023

Temel öznesi birey olan ve diğer bilimlerle en çok ilişkiye sahip olan bilim dalı iktisat bilimidir. İktisadın diğer bilimlerle ilişkisi geçmişten günümüze kadar eleştirilir olmuştur. Eleştiri konusunun odak noktası iktisadın diğer bilim dallarıyla olan ilişkisinde araç-amaç sınırının korunamaması olmuştur. İktisat biliminin diğer disiplinlerle ilişkisi sadece iktisat bilimine değil iktisat eğitimine de yansımıştır. Çalışmanın amacı, iktisadın doğa ve sosyal bilimleri ile olan ilişkisini inceleyip bu ilişkilerin iktisat eğitimine olan yansımasını değerlendirmektir. Çalışmanın sonucuna göre iktisadın diğer bilim dallarıyla olan ilişkisi araç bağlamı korunabilirse iktisat bilimi ve iktisat eğitimine pozitif katkı sağlayacağı yönündedir.
Primary osteogenic sarcoma of breast
Authors: Jwala Srikala
Published: July 2023

A 60-years-old lady presented with a firm to hard mass in right breast. She was investigated with a mammogram and ultrasound which showed a mass of indeterminate nature with extensive calcifications. An ultrasound guided core biopsy of the mass was performed which was reported as a sarcomatous mass and excision biopsy was requested. Excision biopsy concluded that the mass was an osteogenic sarcoma in the background of a phyllodes tumor. Patient underwent a definitive mastectomy two weeks later. Keywords: Primary osteogenic sarcoma; breast cancer; phyllodes tumor
Ectodermal dysplasia and partial anodontia: A case report
Authors: M Prasad
Published: July 2023

Ectodermal dysplasia is a hereditary disorder that occurs as a consequence of disturbances in the ectoderm of the developing embryo. It is usually accompanied by lack of sweat glands and a partial or complete absence of primary and/or permanent dentition. A case report illustrating the prosthetic rehabilitation of a young woman with anhidrotic ectodermal dysplasia associated with partial anodontia and mid facial defect are presented. Since the oral rehabilitation of these cases is often difficult; treatment should be administered by a multidisciplinary team involving orthodontics, prosthodontics and oral-maxillofacial surgery. Keywords: Ectodermal dysplasia; hereditary disorder; anodontia
The strength of restorations of hard tooth tissues with changes in atmospheric pressure, in vitro studies
Authors: Latif Aleka R. , Vorobyeva Yulia B.
Published: July 2023

BACKGROUND: It is known that the development of the carious process is promoted by microorganisms that secrete waste products that penetrate into the tooth tissue during the depressurization of the filling material. That is why high-quality restoration prevents the development of secondary caries.
AIM: Based on the study of the edge fit of restorations made of various types of filling materials, when restoring the chewing surface of the tooth, to determine the most optimal method of filling, which reduces the likelihood of violation of the edge fit of the seal in cases of significant changes in atmospheric pressure.
MATERIALS AND METHODS: The removed teeth were prepared and treated with the Single Bond Universal adhesive system, the samples were divided into 4 groups, the cavities were filled according to the classical method with traditional composite materials Estelite Sigma Quick (Tokuyama Dental), OptiShade (Kerr) and materials of the bulk fill Tetric N-Ceram (Ivoclar Vivadent), SonicFill (Kerr). After sealing, groups 3 and 4 were placed in a pressure chamber (the study was conducted at the Department of Aviation and Space Medicine) and exposed to low atmospheric pressure. Next, the restoration slots were made and the study was carried out using a scanning electron microscope JEOL JSM-6380LV.
RESULTS: As a result of microscopic studies, a violation of the marginal fit along the filling-tooth border was determined in all samples sealed with traditional composite materials (Estelite Sigma Quick, OptiShade) 65 9.18% (p 0.05) and bulk fill group materials (Tetric N-Ceram, SonicFill) 98 2.69%, (p 0.05) in cases of exposure to low atmospheric pressure. In the samples that were not exposed to atmospheric pressure, the marginal depressurization was 12 6.25% (p 0.05) Estelite Sigma Quick, OptiShade and 21 7.84% (p 0.05) Tetric N-Ceram, SonicFill.
CONCLUSION: It has been proved by laboratory method that traditional composite materials and bulk fill group materials are rational to use only in persons who are not associated with extreme effects on the body, since in cases of exposure to atmospheric pressure, there are violations of the marginal fit of the material along the sealtooth border.
Pathophysiological markers of reduced resistance of healthy people to moderate hypoxic hypoxia
Authors: Kim Aleksey E. , Tsygan Vasily N. , Shustov Evgeniy B. , Ganapolsky Vyacheslav P. , Borisova Irina V. , Rzhepetskaya Marina K.
Published: July 2023

BACKGROUND: Despite the abundance of research in the field of high-altitude physiology and medicine, the problem of resistance to moderate hypoxia has not been practically studied. This is partly due to methodological difficulties: the studies were conducted on healthy people and climbers who tolerated the effects of moderate hypoxia well. Such studies have become necessary in connection with the development of hypoxic therapy.
AIM: To search for indicators of the functional state of a person that are highly sensitive to the effects of moderate hypobaric hypoxia.
MATERIAL AND METHODS: The examined group consisted of 65 practically healthy men aged 1925 years who were selected for work in high mountains. The main indicators characterizing the state of the central nervous system, cardiovascular and respiratory systems were studied in a state of relative rest and when performing a dosed two-stage bicycle ergometric test, in normoxia conditions (altitude 0) and during a pressure chamber rise in the TABAY climate complex (Japan) to altitudes of 3500 and 4500 m Statistically analyzed were the characteristics of the dynamics of indicators during the transition from normoxia to states of moderate hypoxia, correlations between indicators, their sensitivity to hypoxic effects, the significance of reactivity to hypoxic effects and mobilization of the bodys functional reserves in resistance to hypoxia.
RESULTS: It has been shown that the key pathophysiological markers of reduced body resistance to moderate hypoxic exposure are a rapid decrease in the level of peripheral blood saturation, high reactivity of the cardiovascular and respiratory systems to hypoxic exposure, as well as excessive mobilization of the bodys functional reserves in response to additional physical activity.
CONCLUSION: The presented materials confirm that the functional state of a healthy person under conditions of moderate hypoxia at rest is determined by the level of saturation of his peripheral blood. Maintaining saturation at a higher level ensures the maintenance of an optimal level of functional state, physical and operator performance, a lower degree of stress on the respiratory and cardiovascular systems.
Recent advances in nanotherapeutics for epilepsy and neurodegenerative diseases
Authors: Kuchik Anant R , Doke Rohit R , Bhor Pranav P , Matade Ritik R , Gosavi Pranav P , Shinde Akash R
Published: July 2023

This review focuses on the potential of nanotherapeutics in the diagnosis and treatment of neuronal abnormal conditions particularly epilepsy, alzheimer's disease (AD), and Parkinson's disease (PD). The advancements in nanotechnology have paved the way for the development of nanocarrier systems that can target the underlying pathogenesis of these diseases. The study aimed to explore the efficacy of nanosystems in treating epilepsy, AD, and PD by analyzing relevant articles from databases such as Medline, PubMed and the national library of medicine. The review discusses the targeted delivery of active therapeutics to the central nervous system, with a focus on modulating neuronal and endothelial cell activity. It highlights various nanotherapeutic approaches, including pH-responsive nanomaterial-based therapeutics, nano-bioelectronic-implantable transient electronic devices, and electro-responsive nanosystems for the treatment of epilepsy. Additionally, the efficacy of nanodrug delivery systems loaded with curcumin, monoclonal anti-tau antibody-coated gold nanoparticles, Polyethylene Glycolpolylactide-Polyglycolide (PEG-PLGA) nanoparticles loaded with lactoferrin, dopamine-conjugated Albumin/PLGA nanosystems, and curcumin-loaded T807/RPCNP nanoparticles against neurodegeneration is discussed. The findings of this review provide valuable insights into the implications and challenges of nanotherapeutics in the field of neurological diseases. Neurologists and clinicians can benefit from this knowledge to better understand the potential applications of nanotherapeutics in the diagnosis and treatment of these conditions.
Saúde Coletiva e suas aproximações com a Terapia Ocupacional: reflexões a partir de uma revisão bibliográfica
Authors: Mei Andre Eduardo , Yoneko Dakuzaku Carretta Regina , Filice de Barros Nelson
Published: July 2023

Introdução: A Saúde Coletiva é um campo de conhecimentos que se destaca pela sua transformação através da inclusão contínua de disciplinas oriundas de diferentes campos científicos, sendo assim irredutível a um paradigma monodisciplinar.  Objetivos: Este estudo buscou explorar possíveis afinidades eletivas entre a terapia ocupacional e a saúde coletiva.  Método: Foi realizada uma revisão de escopo na base de dados da Biblioteca Virtual em Saúde, com os termos “terapia ocupacional”, “saúde coletiva”, “saúde pública” e “saúde comunitária”. Resultados: Sete artigos foram selecionados para a revisão, que tematizaram o universo da gestão, a prevenção de doenças e agravos, a promoção da saúde, o contexto comunitário de práticas, saúde populacional e a dimensão ocupacional do cuidado. Ademais, o estudo pôde perceber nuances sobre conceitos chave e suas definições distintas encontradas na literatura. Conclusão: O presente artigo pode alimentar o debate acerca das afinidades eletivas entre terapia ocupacional e saúde coletiva, bem como embasar o conhecimento de terapia ocupacional na saúde coletiva.
Evaluación de la gestión de recetas en un servicio farmacéutico de un hospital especializado
Authors: Gines Cantero Larissa Andrea , Acosta Recalde Patricia Guadalupe , Doménech María Gloria , Samaniego Silva Lourdes Raquel , Maidana de Larrozae Gladys Mabel
Published: July 2023

Error de medicación es cualquier incidente prevenible que puede causar daño al paciente o dar lugar a una utilización inapropiada de los medicamentos, cuando estos están bajo el control de los profesionales sanitarios o del paciente, con potenciales consecuencias para estos últimos. En Paraguay las enfermedades respiratorias crónicas (epoc, asma, etc.), junto con la diabetes, los problemas cardiovasculares y el cáncer son responsables de una alta morbi-mortalidad, registrando una prevalencia que va en aumento. Esta investigación tuvo el objetivo de evaluar las recetas prescriptas en el consultorio externo de un hospital especializado en enfermedades respiratorias y dispensadas en la farmacia, gracias a un estudio observacional de corte transversal, retrospectivo, y un muestreo no probabilístico que consistió en la revisión de recetas médicas de pacientes que acudieron al consultorio del Instituto Nacional de Enfermedades Respiratorias y del Ambiente durante los meses de septiembre de 2015 y 2016. Los datos se registraron en planillas. Se analizaron 4828 recetas, de las cuales 2421 corresponden al mes de septiembre del 2015, y 2407 recetas que corresponden al mes de septiembre del 2016. Los errores técnicos de prescripción más frecuentes fueron la ilegibilidad y la ausencia de dosis e indicación. Por ello, se plantea la importancia de establecer un programa de gestión de riesgos en los hospitales, para implementar nuevas tecnologías que faciliten la prescripción.
Characterization of the biochemical composition and antioxidant activity of Spinacia oleracea L. and Spinacia turkestanica Iljin.: a comparative study
Authors: Sokolova D. V. , Solovieva A. E.
Published: July 2023

Spinach is an economically important vegetable crop widely cultivated and consumed worldwide. This early ripening leafy vegetable is rich in bioactive components, fiber, micro and macro elements, vitamins, and has high antioxidant activity. Results of numerous studies on the effects of spinach on human health confirm its beneficial effect. The species S. oleracea L. is cultivated commercially. The ancestor of cultivated spinach is S. turkestanica Iljin, which has a breeding potential for different economically valuable traits. Its biochemical composition has been studied extremely little. The present article offers a comparative evaluation of the biochemical profile and antioxidant activity of cultivated and wild spinach species. The material for the study was a representative sample of 48 collection accessions of spinach from the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR). The accessions were grown in 2019 and 2020 in the open ground of the Pushkin and Pavlovsk Laboratories of VIR. The antioxidant activity was studied spectrophotometrically by the DPPH assay of free radical scavenging at a wavelength of 515 nm. A significant similarity of the two species in most biochemical parameters was revealed, which confirms their phylogenetic relationship. Significant differences were found in the content of phenolic elements, which determine the elevated values of antioxidant and antiradical activity of S. turkestanica. The article presents correlation matrices of species biochemical composition, describes general trends, negative relationships and conjugated factors. The identified promising accessions of both cultivated and wild spinach are recommended for breeding for increased content of phenolic compounds, ascorbic acid and antioxidant activity. The result of the study helps to reveal the potential of the crop as a valuable source of bioactive components and high antioxidant activity.
Ecological testing of melon varieties bred at the Bykovskaya Experimental Station
Authors: Varivoda E. A. , Lazko V. E. , Taishibaeva E. U.
Published: July 2023

Relevance and methodology. Currently, due to changing weather conditions, the cultivation of melons and gourds is shifting to areas that were not previously engaged in melon growing. Therefore, the testing of available varieties in various environmental conditions is relevant. The purpose of this work is to evaluate melon varieties bred at the Bykovskaya melon breeding experimental station in various soil and climatic conditions. Three varieties of melon were used as the object of research. The tests were carried out in the conditions of the Volgograd region, the Krasnodar region and the Republic of Kazakhstan. During the research, the melon varieties were evaluated according to the following indicators: yield, duration of the growing season, dry matter content.Results. As a result of the research, it was revealed that the variety Harmonia was the most stable in terms of the duration of the growing season (75-79 days). A consistently high content of dry matter in all areas of the study was in the varieties Comet and Idyll from 12.0 to 15.0%. All varieties had a good tasting score. The average fruit weight of all melon varieties grown in Krasnodar and the Volgograd region was at the same level. The high average weight in the conditions of Kazakhstan was distinguished by the Idyll variety - 4.3 kg. The melon varieties Harmoniya and Idyllia have a consistently high yield in all three zones. The variety Kometa had the highest yield in the conditions of Kazakhstan - 16.3 t/ha. Thus, melon varieties that have been tested in different regions of cultivation have high quality indicators and yields and are suitable for growing marketable products in the regions of the study.
Implementing Effective Care Through Utilization of Diabetes-Focused “Right Care” Visits in a Suburban Primary Care Setting
Authors: Neu Tricia , Eppley Christopher , Gianelis Kristin
Published: July 2023

Background:Diabetes is the seventh leading cause of death in the United States and the leading cause of lower limb amputations, adult-onset blindness, and renal failure. It is estimated that 34.2 million Americans have a diabetes diagnosis, and the prevalence of this condition has continually increased over the last two decades. This study includes patients at a large, suburban primary care practice in southwest Ohio who were considered to have uncontrolled diabetes based on their last Hemoglobin A1c of greater than 9%. Compliance with recommended annual screenings among this population was 15%.Objectives:The aim of this project was to improve glycemic control and increase the number of patients who received the recommended annual screenings through the implementation of nurse practitioner-driven, diabetes-focused “Right Care” visits.CMethods:This quality improvement pilot study consisted of interventions implemented over the four plan-do-study-act cycles. Each cycle included a test of change that was identified based on data from previous cycles to ensure continuous improvement throughout project implementation. Four interventions were evaluated including the utilization of a diabetes registry, implementation of a “Right Care” checklist during “Right Care” visits, use of a patient engagement tool with a focus on individualizing diabetes medication regimens, and implementation of a team-engagement plan.Results:Average Hemoglobin A1c reduction was 2.4% post-“Right Care” visit. Compliance with the annual screening bundle increased to 44% over 8 weeks. Utilization of the patient/provider relationship increased visit compliance by 18%, and the team engagement plan decreased work-related stress by 12%.Conclusions:The implementation of “Right Care” visits led to improved glycemic control and increased compliance with the recommended annual screenings among patients with an A1c greater than 9%. The patient engagement tool identified key factors related to diabetes medication adherence and team engagement decreased work-related stress and improved annual fundoscopic exam screening compliance.Implications for Nursing:Nurse practitioner-led “Right Care” visits utilize the knowledge and skills of advanced practice registered nurses to improve glycemic control in patients with uncontrolled diabetes.
Functional-semantic type of substantive word adverbialization form “boon”
Authors: Shigurov Victor V. , Shigurova Tatyana A.
Published: July 2023

The study relevance is due to the need for a comprehensive interdisciplinary mechanism analysis of transposition in the language, which generates a huge layer of grammatical and lexical-grammatical homonyms, as well as syncretic (peripheral and hybrid) structures that allow economically, but capaciously expressing thoughts and feelings of a person. While studying the steps of adverbial transposition substantive word forms, the patterns of interaction between semantic and grammatical in the formations structure explicating in typical contexts the core and periphery nouns zones and the peripheral and nuclear substantive adverbs formed on their basis were revealed. On the example of the word form “boon”, different degrees of its departure from the nouns class and approaching the adverbs class are demonstrated. As a applying result the methodology of oppositional analysis and indexing, it has been established that in the zone of the adverbs core it finds, on the one hand, 0 % of the correspondence of its differential features to the original nuclear noun “boon” features, and on the other hand, 80 % of the correspondence to the differential substantive nuclear adverb “circle” features. The idea is substantiated that 100 % correspondence of the properties of different prototypical adverbs in the structure of any nuclear adverb is unlikely due to individual semantic and syntactic differences of adverbial lexemes, including their accentological features. The study results can be used in further developments on the problem of transposition and syncretism in the system of parts of speech and interpartial semantic-syntactic categories.
An examination of teacher collaboration in professional learning communities and collaborative teaching practices
Authors: Khasawneh Yusra Jadallah Abed , Alsarayreh Raghad , Ajlouni Adnan Ahmad Al , Eyadat Haitham Mustafa , Ayasrah Mohammad Nayef , Khasawneh Mohamad Ahmad Saleem
Published: July 2023

The present study aims to examine the influence of teacher collaboration within professional learning communities (PLCs) and collaborative teaching practices on both the professional growth and academic achievement of students. The study employed a mixed-methods research design that  incorporated both qualitative and quantitative research methodologies. This research comprises both survey responses and interview transcripts obtained from K-12 educators who are currently engaged in Professional Learning Communities (PLCs) or collaborative teaching methodologies. The findings of this study have the potential to enhance the existing literature on teacher collaboration and furnish educators, policymakers, and researchers with valuable perspectives to steer optimal strategies for promoting effective teacher collaboration in Professional Learning Communities (PLCs) and collaborative teaching approaches. The objective of the research is to investigate the influence of teacher collaboration within Professional Learning Communities (PLCs) and collaborative teaching practices on the development of professional skills and academic achievements of students. The results of this study underscore the importance of recognizing the advantageous effects that collaborative teaching methodologies can have on the academic achievements of students. This necessitates the provision of adequate time for collaborative activities, encouraging supportive leadership within educational institutions, and allocating sufficient resources for collaboration.
Elastic Adaptively Parametric Compounded Units for Convolutional Neural Network
Authors: Zhang Changfan , Xu Yifu , Sheng Zhenwen
Published: July 2023

The activation function introduces nonlinearity into convolutional neural network, which greatly promotes the development of computer vision tasks. This paper proposes elastic adaptively parametric compounded units to improve the performance of convolutional neural networks for image recognition. The activation function takes the structural advantages of two mainstream functions as the function’s fundamental architecture. The SENet model is embedded in the proposed activation function to adaptively recalibrate the feature mapping weight in each channel, thereby enhancing the fitting capability of the activation function. In addition, the function has an elastic slope in the positive input region by simulating random noise to improve the generalization capability of neural networks. To prevent the generated noise from producing overly large variations during training, a special protection mechanism is adopted. In order to verify the effectiveness of the activation function, this paper uses CIFAR-10 and CIFAR-100 image datasets to conduct comparative experiments of the activation function under the exact same model. Experimental results show that the proposed activation function showed superior performance beyond other functions.
Multimodal Facial Emotion Recognition Using Improved Convolution Neural Networks Model
Authors: Udeh Chinonso Paschal , Chen Luefeng , Du Sheng , Li Min , Wu Min
Published: July 2023

In the quest for human-robot interaction (HRI), leading to the development of emotion recognition, learning, and analysis capabilities, robotics plays a significant role in human perception, attention, decision-making, and social communication. However, the accurate recognition of emotions in HRI remains a challenge. This is due to the coexistence of multiple sources of information in utilizing multimodal facial expressions and head poses as multiple convolutional neural networks (CNN) and deep learning are combined. This research analyzes and improves the robustness of emotion recognition, and proposes a novel approach that optimizes traditional deep neural networks that fall into poor local optima when optimizing the weightings of the deep neural network using standard methods. The proposed approach adaptively finds the better weightings of the network, resulting in a hybrid genetic algorithm with stochastic gradient descent (HGASGD). This hybrid algorithm combines the inherent, implicit parallelism of the genetic algorithm with the better global optimization of stochastic gradient descent (SGD). An experiment shows the effectiveness of our proposed approach in providing complete emotion recognition through a combination of multimodal data, CNNs, and HGASGD, indicating that it represents a powerful tool in achieving interactions between humans and robotics. To validate and test the effectiveness of our proposed approach through experiments, the performance and reliability of our approach and two variants of HGASGD FER are compared using a large dataset of facial images. Our approach integrates multimodal information from facial expressions and head poses, enabling the system to recognize emotions better. The results show that CNN-HGASGD outperforms CNNs-SGD and other existing state-of-the-art methods in terms of FER.