bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of immunophenotypic markers and clinico-hematological findings in chronic lymphocytic leukemia
Authors: Mazin Butrous Ansam , Sadiq Muhammad Newsherwan
Published: December 2023

Background and objective: Chronic lymphocytic leukemia (CLL) is a clonal, mature B-cell neoplasm, its clinical features, cell morphology, and immunophenotyping are used to establish the diagnosis. Immunophenotyping by flow cytometry is the most accurate procedure for diagnosing CLL, there is no single marker exclusively expressed in CLL, however, a complex of immunophenotypic markers that incorporates several B-cell markers and assists in differentiating CLL from other mature B-cell neoplasms, the expression of these immunophenotypic markers is considered in the specific CLL scoring system (Moreue scoring system).this study aimed to assess the clinico – hematological features and immunophenotypic characteristics of CLL patients and to assess the role of immunophenotyping in the differential diagnosis of CLL. Methods: an observational prospective and retrospective study was carried out at Nanakaly hospital for blood diseases and oncology in Erbil city, Iraq. That was conducted on 100 patients newly diagnosed with mature B cell neoplasm which included 68 cases of CLL and 32 cases with other mature B cell neoplasm (MBN), usinga convenience sampling method. The study period was from the1st of September 2021 to the end of April 2022. An interview questionnaire was used to collect the study data from the patients. Results: The mean of age ± standard deviation of the CLL patients (58.85 ± 10.69) years and (66.2%) was male, The most frequent clinical presentations for CLL cases were fatigue (50%), lymphadenopathy (41.2%), and splenomegaly (41.2%), (50%) of CLL patients had anemia, thrombocytopenia was seen in (32.4%) and leukocytosis was seen (98.5%), all patients had lymphocytosis and (97%) had an absolute B lymphocyte count of more than 5 x109 /L. all the studied CLL patients expressed both CD45 and CD19 markers, the expression of the immunophenotypic markers was as following: CD5 (98.5%), CD23 (97.1%) and CD200 (97.1%), Half of the patients (50%) showed expression of monoclonal lambda light chain, sIgM (4.4%), CD20 (88.2%) and CD43 (54.4%) and CD38 (26.5%). The expression of the following marker had a significant role in the differentiation between CLL and other MBN: CD5, CD23, CD79b, FMC7, sIgM, CD200, and CD43. Conclusion: Our results have shown that the clinical presentations and hematological profile of Iraqi CLL patients were not significantly different from that of previous local and global studies, the distinct immunophenotyping, as well as it has been found that immunophenotyping is a promising method for supporting the clinical and morphological characterization of CLL.
The next generation sequencing among epileptic children in Erbil city, Kurdistan region, Iraq
Authors: Adil Abdulqadir Talib , Anwar Hamad Azad
Published: December 2023

Background and objective: Causes of epilepsy are different and the genetic component is hidden and provides an essential role in emergence of drug resist epilepsy .The aim of this study is to know the diagnostic yield of Whole exome sequence in pediatric epilepsy and its contribution in giving information about diagnosis of the epilepsy syndrome, possible preventive actions or treatment. Methods: 60 children (6 weeks - 14 year) with drug resistant epilepsy, family history of epilepsy or child with diagnosis of epilepsy syndrome were enrolled in this cross sectional study. The study was done in Raparin pediatric teaching hospital in Erbil city from beginning of May 2021 to the end of April 2022.Demographic, clinical, MRI finding and genetic background using whole exome sequence were checked and analyzed. Results: 33/60 (55%) of participants were male. The NGS (Next Generation sequence) study revealed: 13 (21%) pathogenic, 10 (17%) likely pathogenic, 21 (35%) variance of unknown significance and 16 (27%) negative result. The diagnostic yield by NGS for pathogenic or likely pathogenic is 38%. The positive findings were more relevant among female (P value = 0.04), children with age onset of seizure≤ 1 year of (P value = 001) and history of lack of sleep (P value = 0.02). Genetic diagnosis lead to change of treatment in 11/60 (18.3%) candidates. Conclusion: The diagnostic genetic test by NGS is relevant in epileptic child especially among children with age of onset of seizure ≤ 1 year, sex, and lack of sleep. It is recommended to test the negative result periodically and more research to investigate impact of NGS on seizure freedom.
Event Integration and Temporal Differentiation: How Hierarchical Knowledge Emerges in Hippocampal Subfields through Learning
Authors: Bein Oded , Davachi Lila
Published: December 2023

Everyday life is composed of events organized by changes in contexts, with each event containing an unfolding sequence of occurrences. A major challenge facing our memory systems is how to integrate sequential occurrences within events while also maintaining their details and avoiding over-integration across different contexts. We asked if and how distinct hippocampal subfields come to hierarchically and, in parallel, represent both event context and subevent occurrences with learning. Female and male human participants viewed sequential events defined as sequences of objects superimposed on shared color frames while undergoing high-resolution fMRI. Importantly, these events were repeated to induce learning. Event segmentation, as indexed by increased reaction times at event boundaries, was observed in all repetitions. Temporal memory decisions were quicker for items from the same event compared to across different events, indicating that events shaped memory. With learning, hippocampal CA3 multivoxel activation patterns clustered to reflect the event context, with more clustering correlated with behavioral facilitation during event transitions. In contrast, in the dentate gyrus (DG), temporally proximal items that belonged to the same event became associated with more differentiated neural patterns. A computational model explained these results by dynamic inhibition in the DG. Additional similarity measures support the notion that CA3 clustered representations reflect shared voxel populations, while DG’s distinct item representations reflect different voxel populations. These findings suggest an interplay between temporal differentiation in the DG and attractor dynamics in CA3. They advance our understanding of how knowledge is structured through integration and separation across time and context.
Visual Stimuli Modulate Local Field Potentials But Drive No High-Frequency Activity in Human Auditory Cortex
Authors: Ahveninen Jyrki , Lee Hsin-Ju , Yu Hsiang-Yu , Lee Cheng-Chia , Chou Chien-Chen , Ahlfors Seppo P. , Kuo Wen-Jui , Jääskeläinen Iiro P. , Lin Fa-Hsuan
Published: December 2023

Neuroimaging studies suggest cross-sensory visual influences in human auditory cortices (ACs). Whether these influences reflect active visual processing in human ACs, which drives neuronal firing and concurrent broadband high-frequency activity (BHFA; >70 Hz), or whether they merely modulate sound processing is still debatable. Here, we presented auditory, visual, and audiovisual stimuli to 16 participants (7 women, 9 men) with stereo-EEG depth electrodes implanted near ACs for presurgical monitoring. Anatomically normalized group analyses were facilitated by inverse modeling of intracranial source currents. Analyses of intracranial event-related potentials (iERPs) suggested cross-sensory responses to visual stimuli in ACs, which lagged the earliest auditory responses by several tens of milliseconds. Visual stimuli also modulated the phase of intrinsic low-frequency oscillations and triggered 15–30 Hz event-related desynchronization in ACs. However, BHFA, a putative correlate of neuronal firing, was not significantly increased in ACs after visual stimuli, not even when they coincided with auditory stimuli. Intracranial recordings demonstrate cross-sensory modulations, but no indication of active visual processing in human ACs.
Navegando la Adversidad y la Oportunidad. Liderazgo Escolar en Tiempos de Crisis
Authors: Pascual Javier , Orrego Vanessa , Cheyre Manuel , Iturrieta Consuelo
Published: December 2023

Ante la crisis educativa derivada de la pandemia y la escasa investigación nacional sobre liderazgo educativo en crisis, el presente artículo buscó identificar ejemplos de prácticas de liderazgo directivo en tiempos de crisis que permitieron a algunos establecimientos sostenerse e incluso avanzar durante la pandemia y postpandemia por Covid-19. La metodología fue cualitativa, basada en 30 entrevistas semiestructuradas a directivos y docentes de escuelas y liceos de Chile. Los resultados evidencian la emergencia de las prácticas asociadas a la continuidad del proceso de enseñanza-aprendizaje, la priorización del bienestar de la comunidad, la toma de decisiones críticas, la comunicación asertiva, la flexibilidad, el incentivo a la reflexión y la distribución del liderazgo. Concluimos que existe un vínculo entre las distintas prácticas que debe reconocerse para avanzar hacia un enfoque más integral del mejoramiento educativo, al tiempo que, se invita a la academia y a la política pública a cambiar de paradigma para entender las crisis como eventos periódicos que implican estudiar y fortalecer liderazgos que permitan enfrentarlas en el futuro
Dos categorías de resistencia anticolonial entre los palestinos del 48 ante el espejismo de la ciudadanía liberal. Los acontecimientos de la Primavera de 2021 como caso de estudio.
Authors: Domínguez de Olazábal Itxaso
Published: December 2023

En el transcurso del año 2021, diversos eventos en la Palestina histórica arrojaron luz sobre las distintas posturas políticas y el conjunto de prácticas que actualmente predominan entre el pueblo palestino frente al carácter estructural de su vínculo con el estado de Israel. Este artículo se basa en un marco teórico que conceptualiza el contexto en la Palestina histórica y, por tanto, el marco en el que se inscriben los ciudadanos palestinos de Israel (‘palestinos del 48’), como un caso de colonialismo de asentamiento, en contraposición a la visión de Israel como una etnocracia, una democracia liberal que presenta insuficiencias relacionadas con el trato a esta y otras minorías. Partiendo de dos acontecimientos significativos para el pueblo palestino en la primavera de 2021, las elecciones legislativas en Israel y la denominada 'Intifada de la Unidad', el artículo busca exponer algunas de las prácticas que caracterizan las dos principales categorías de resistencia anticolonial adoptadas por los palestinos del 48, quienes se enfrentan al ilusorio concepto de ciudadanía liberal. Estas prácticas delinean los perfiles de dos categorías de resistencia anticolonial: una resistencia transigente que se ajusta al sistema colonial, utilizando las vías previstas por este para lograr mejoras, principalmente de índole material, y avanzar hacia una mayor igualdad formal. Por otro lado, se destaca una resistencia oposicional fundamentada en el rechazo frontal al proyecto colonial, basándose en la voluntad de desmantelar dicho proyecto y proponer alternativas surgidas de un proceso completo de descolonización. El análisis de los dos acontecimientos del año 2021, junto con la exploración de dos textos primarios, el Manifiesto de la Dignidad y la Esperanza, y el Manifiesto 'Seguimos Creyendo', contribuirá a identificar una serie de prácticas, discursivas y de otra índole, que caracterizan cada categoría de resistencia anticolonial.
La acción exterior de Catar en el estándar de “pequeño Estado”. Multilateralismo e influencia
Authors: González del Miño Paloma
Published: December 2023

Desde hace poco más de dos décadas Catar se ha ido transformando en un actor con relevancia geoestratégica y una política exterior más asertiva y autónoma que se aleja de los estándares clásicos de los “pequeños Estados”. La intensificación de su influencia regional e internacional debido a la pujante economía, a los recursos de los hidrocarburos y a una diplomacia de “protección” consistente en maximizar el número de aliados, no exenta de cuestionamiento, posibilitan que el emirato desempeñe un dominio superior en relación con su tamaño y población. El marco temporal del artículo abarca desde la llegada al poder del emir Hammad bin Khalifa Al Thani a mediados de la década de 1990 a la actualidad, utilizando el marco teórico Foreign Policy Analysis (FPA) mediante la conducta y la práctica de las relaciones entre actores internacionales.
La política migratoria de Marruecos como recurso de seguridad y diplomacia: equilibrios e intereses
Authors: Delkáder-Palacios Augusto
Published: December 2023

En 2013, el rey Mohamed VI anunció la Nueva Política Migratoria. Esta iniciativa supuso un cambio de paradigma en la gobernanza de la migración en Marruecos porque aportó una perspectiva no exclusivamente securitizada del fenómeno migratorio y definió a Marruecos como país de destino. Pensada como una política desde África y para África, tuvo implicaciones relevantes para la cooperación migratoria de Marruecos con la UE y con los países africanos. El tiempo ha demostrado que este es un equilibrio muy difícil de mantener. Analizamos las motivaciones de Marruecos con esta política, sus resultados y sus efectos en el panorama internacional.
The Reality Of Emotional Balance Among Gifted Students In The Middle Schools In Haifa District
Authors: Dakhlallah Nijmeh Mahmoud
Published: December 2023

The current study aimed to measure emotional balance among gifted students in middle school. The study sought to examine the type of differences in the average responses of gifted children on the emotional stability scale for gifted students in the Haifa District due to the variables of gender, academic grade, school achievement, residential area , and parents’ educational level. A questionnaire was used to measure emotional balance, and the study sample consisted of (72) gifted middle school students in the Haifa District, who were selected randomly and intentionally from the study population of (200) male and female students. The results revealed that the level of emotional balance among gifted students in middle schools in the Haifa District came in large degrees and very high levels, meaning that there was a high degree of emotional balance among gifted students. The results showed that there were no statistically significant differences at the significance level (0.05 > a). In the responses of gifted students to a measure of emotional stability among gifted students in middle schools in the Haifa district, due to the variables of gender, grade, school achievement, residential area, and parents’ educational level.
Breaking the Myth of the „Chinese Wall“
Authors: Tarvydaitė Dominyka
Published: December 2023

Apie Leono Nekrašo disertaciją „„Pafrontė“: Valstybė ir visuomenė Lietuvos pasienyje su Lenkija 1920–1939 m.“ ir jos gynimą / On Leonas Nekrašas’ Thesis „„Frontline Area“: State and Society in Lithuania’s Borderland with Poland in 1920–1939“
Jolanta Zabarskaitė, 2022, Kaip kalba gamina prasmę. Kognityvinės semantikos tyrimai komunikacijos požiūriu, Vilnius: Kazimiero Simonavičiaus universitetas.
Authors: Kardelis Vytautas
Published: December 2023

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The effective use of remainder term estimation in the limit theorems
Authors: Skrabutėnas Rimantas
Published: December 2023

We investigate the asymptotic behavior of mean value of multiplicative arithmetic function from the class M1(G). In the present paper the asymptotic formula under special condition on prime elements of Knopfmacher’s semigroup G is obtained.
Models for predicting juvenile hypertension
Authors: Janilionis Vytautas , Janavičiūtė Edita , Klumbienė Jūratė , Sakalauskienė Giedrė
Published: December 2023

Aim of present study was to create some models to predict juvenile hypertension. Data was taken from longitudinal study of Juvenile hypertension in Lithuania. The first survey of a random sample of Kaunas schoolchildren born in 1964 was carried out in 1977. This population was re-examined in 1989, in 1997 and the last survey took place in 2002. There were created models for predicting juvenile hypertension using real data. The models were created using logistic regression, nonparametric discriminant methods (kernel and k-nearest neighborhood) and system SAS. The best results were received using nonparametric discriminant analysis.
On characterization of the Cauchy law by sample mean properties
Authors: Januškevičius Romanas
Published: December 2023

The characterization of Cauchy distribution by assuming the identical distribution of a monomial and sample mean has been considered by B. Ramachandran, C.R. Rao, Y.H. Wang and other authors. The new proofs of Ramachandran-Rao and Wang's theorem are proposed in our paper.
Stochastic differential equations with bad coefficients: a short note on the weak approximations
Authors: Lenkšas Antanas
Published: December 2023

There is not abstract.
Modeling cable-pulley deployment systems of transformable rod structures
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Shamakhanov V. K. , Khoroshylov S.V. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine
Published: December 2023

The aim of this article is to develop a simplified method for modeling cable-pulley deployment systems of rod structures based on the calculation of cable tensions and nodal driving forces with account for friction and other features of the system. Methods of theoretical mechanics, multibody dynamics, numerical integration of differential equations, and computer modeling were used during the research. The task of developing a simplified approach to modeling cable-pulley deployment systems for rod structures is considered. It is proposed to determine nodal driving forces by calculating cable tensions with account for friction and other features of the cable-pulley system, cables, and pulleys. To develop a model of cable-pulley deployment system, a rod system was chosen as the research object, which represents two sections of the transformable support truss of a reflector. Each section consists of diagonal and horizontal rods with tubular cross-sections. The sections are interconnected by hinge units. The structure is deployed using an upper and a lower cable, which pass through pulleys and are tensioned by an electric motor. The deploying forces are implemented by transferring the cable tension forces to the structure due to static friction and pressure between the cables and the pulleys. For further implementation of the model in an open-source software package, some simplifications were made due to the complexity of the design. A simplified method was developed for nodal driving force calculation in simulating rod structure deployment with the help of cables. The tensions, elongations, slacks, and neutral length of the cables and the forces transmitted from the cables to the pulleys were calculated as a function of time. Using them, the deployment of a rod structure was simulated for a constant cable speed. The results make it possible to control the rod system deployment time and rate depending on the characteristics and tension forces of the cables. The proposed approach is implemented using open-source software, and it provides modeling flexibility and reduces the model development and run time.
Wheel profile of a freight car with prospective trucks for the combined operation on the Ukrainian and European railways
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Mokrii T.F. , Malysheva I.Yu. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Pasichyk S.S. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine
Published: December 2023

To solve the important problem of speeding up the integration of Ukraine into the European railway transportation, an interest has recently grown in the introduction of automatic car transfer from one track gauge to another using gauge-changeable wheelsets, thus dispensing with truck exchange or transshipment and thereby significantly shortening the delivery time. However, the combined operation of trains on the Ukrainian (1,520 mm gauge) and European (1,435 mm gauge) railways calls for the compatibility of the wheel-rail contact pair on both railways: R65 rails and a cant of 1/20 in Ukraine and UIC60 rails and a cant of 1/40 in Europe. The goal of this work is to develop a wheel profile for a freight car with prospective 18-7020 trucks for combined operation on the Ukrainian and European railways and predict the ride performance of a car with that wheel profile and its dynamic interaction with rails on both railways. An investigation was conducted into the wheel?rail interaction indices and the ride performance of a freight car with prospective 18-7020 trucks and wheels with existing profiles. It was shown that it is expedient to develop a new wheel profile to improve the service compatibility of the Ukrainian and European networks. A number of new wheel profiles were constructed, the efficiency of each profile in terms of dynamic stability at service speeds and wheel flange wear on the Ukrainian and European railways was calculated, and a compromise profile, ITM-73ES, was chosen. It was shown that the use of the chosen profile in a car with 18-7020 trucks will offer a high dynamic performance and improved indices of wheel?rail interaction for both truck gauges.
Intercultural Communications in Levko Yurkevych’s Ethnographic Survey
Authors: Kushnir Viacheslav
Published: December 2023

The article deals with the text of Levko Yurkevych’s manuscript about the Pokodyma gentry as of 1927. The main attention is paid to the topic of ethnographic nature, which is directly related to such issues as the ethnic composition of the Pokodyma region population in the Balta district, the planning of settlements, estates, household and customary-ritual complex of the Polish gentry is considered as a real subject of intercultural interaction. These materials illustrate the dynamics of the level of identity of the Poles of the Pokodyma. Levko Yurkevych describes Pokodyma as a territory where representatives of different nationalities and social groups live and communicate. In the late 19th and early 20th centuries, in the Balta district, a significant percentage of the population, in addition to Ukrainians, were Moldovans and Jews. The Poles, in this context the Polish gentry, stood out among others for a number of features of their customary and ceremonial culture and, despite their relatively small number, played a significant role in the history of the district, but not sufficiently studied primarily at the local level. Comparing different ethno-cultural traditions, the researcher traces the results of the interaction between at least four of these communities and draws attention to the gentry, which at the beginning of the 20th century was still an active participant in economic, social and cultural processes, but as a numerically smaller community, was gradually integrating into the Ukrainian socio-cultural space and only certain customary practices and belonging to the Catholic Church still performed an important consolidating function and remained the basis of Polish self-identification. The text of the manuscript reflects the process of acculturation of the Polish gentry, which confidently mastered the Ukrainian language of communication, moved from the Roman Catholic rite to the Orthodox rite, lost other identifying features, and transformed from an ethnic group into an ethno-social group.
Harvest Prediction by Residents of Ukrainian Polissia: аn Agrometeorological Experience
Authors: Vasianovych Oleksandr
Published: December 2023

Scientists of various fields of knowledge are always interested in the traditional experience of people in order to involve it in practical activities. All peoples have many signs by which they determine whether the year will be fruitful or not. This can be considered most consistently on the example of studying folk meteorology. The purpose of the publication is to identify general regional features and local peculiarities of crop forecasting by residents of Ukrainian Polissia as per weather phenomena, based on field materials collected during 2002–2019 in the northern districts of Volyn, Rivne, Zhytomyr, Kyiv, and Chernihiv regions and from emigrants from the Chornobyl exclusion zone using the author’s questionnaire. The methodology of the publication is based on general scientific principles and basic requirements that are put forward to works of historical and ethnological direction. To achieve the set goal, rational and irrational signs are used as predictors of the peasant’s well-being, in particular, observations of the first thunder, snow, hoarfrost, and icicles. An important criterion for prediction was the day of the week when snow or frost first fell. Attention is drawn to the Christmas holidays, which were a certain nodal point for predicting the next year’s harvest by inhabitants of Polissia. Phonetic coincidences of word forms when predicting the harvest are noticed. Since agriculture was the main form of livelihood for Ukrainians in Polissia, many meteorological signs aimed at predicting the future harvest with minor local features within the region have been preserved in folk practice. In this way, the practical possibility of using folk experience as indicators of the terms of field work and various agrotechnical measures is confirmed. The use of the positive experience of traditional agrometeorology (after appropriate verification by specialists) can be useful in modern agricultural practice, considering their general regional and local features.
Ukrainian Territory A Artistic Agency: a Synthesis of Ukrainian Folklore and Popular Music Art in Sound Recording
Authors: Kocherzhuk Denys
Published: December 2023

The basic principles of the development and synthesis of Ukrainian popular and folk (folklore) art of the late 20th – early 21st centuries are investigated in the article. Peculiar attention is paid to the work of the Territory-A artistic agency (ideologist and project masters are producer Oleksandr Bryhynets, presenter – Honored Artist of Ukraine Anzhelika Rudnytska), which managed to find the methods and forms of introducing Ukrainian culture into radio and television spaces, to replenish the creative fund with sound recordings of Ukrainian origin, to distribute popular song in modern arrangements in the mass-media spaces and to popularize Ukrainian folk traditions among young people by initiating festivals called EthnoWinter, EthnoSpring, EthnoSummer and EthnoAutumn. The main analysis of the synthesis of Ukrainian popular music and folklore is dedicated to the theme of revival of archetypal tunes of Western Ukraine, the creation of new compositions based on them and their popularization among the audience, the promotion of ethnic music on television and its importance for national culture in general. Also noteworthy is the first Ukrainian large-format Territory-A hit parade on ICTV channel, which has broadcasted domestically produced videos three times a week for five years (1995–2000), on the revealing new names of young performers as a leading prototype for subsequent art projects such as Star Factory, X-Factor, The Voice of the Country, etc. Besides, attention is focused on the issue of the Musical Week newspaper, which has improved eventually the style of magazine published works. The Territory-A artistic agency is known as the publisher and order performer, famous for its hit parades of video- and audiography among Ukrainian popular music artists on the ICTV All-Ukrainian TV channel. It is emphasized in the conclusions on the necessity of such artistic ideas in the future. This, in turn, positions the revival of national culture and symbolism in the sphere of self-identification of Ukrainian art among the people of other cultures.
Botrychium virginianum (Ophioglossaceae), a new species for the flora of Volyn Polissia (Ukraine)
Authors:   Institute of Ecology of the Carpathians, National Academy of Sciences of Ukraine, Lviv, Ukraine, Danylyk I.M. , Volodymyrets V.O. ,   National University of Water and Environmental Engineering, Rivne, Ukraine, Kuzyarin O.T. ,   State Natural History Museum, National Academy of Sciences of Ukraine, Lviv, Ukraine
Published: December 2023

During floristic surveys conducted in the southern part of Volyn Polissia (Rivne Region) in July 2021, a rare and relict species, Botrychium virginianum (Ophioglossaceae), was discovered for the first time in this area. According to the Ukrainian sozological data, the species is included in the category Endangered; using the IUCN categorization, it is considered as a Critically Endangered (CR) species of the flora of Ukraine. In Ukraine, where the southern border of the species range is located, 30 localities have been recorded until present, most of them prior to the first half of the 20th century. The reported location of B. virginianum is associated with the carbonate uplift of the first floodplain terrace of the right bank of the Horyn River within the boundaries of the Kostopil-Berezniv physiographic district of Volyn Polissia. A small local population consists of at least five individuals with high vitality. The ecological and phytocenotic conditions of the reported species habitat have been studied and its limiting factors have been clarified. It is recommended to include this site with a cluster of rare species of the flora in the Suskyi Botanical Reserve of national importance, which is located nearby.
Presentación del caso
Authors: Fernández Claudio Alfredo , Moreiro María Emilia , Miranda María Gabriela
Published: December 2023

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ensino e a aprendizagem da matemática nos anos iniciais
Authors: Marques dos Santos Rafael , Braga Laudelina , Maria Luft Hedi
Published: December 2023

Esta pesquisa contribuirá para discutir a importância da formação inicial ofertada na modalidade do Curso Normal, que tem por finalidade a formação de professores que atuarão nos anos iniciais. Nesse movimento, oportunizamos a escrita narrativa a fim de favorecer reflexões advindas das vivências no contexto escolar durante as intervenções de estágio nos anos iniciais. Nesse sentido, a escrita das narrativas resgata indicativos do ser professor, dos modos de ensinar e aprender matemática, as percepções sobre as relações entre os procedimentos metodológicos de ensino da matemática e a dicotomia entre a teoria e a prática no desenvolvimento de práticas pedagógicas no período de estágio. Assim, o objetivo desta investigação consiste em analisar as narrativas das normalistas em formação, abarcando as experiências no processo de ensino e aprendizagem de matemática nos anos iniciais numa perspectiva histórico-cultural. A pesquisa apresenta-se como sendo de abordagem qualitativa com características da pesquisa narrativa. Evidenciamos que a escrita reflexiva, por meio dos diários de bordo, possibilitou experienciar o ensino e a aprendizagem da matemática nos anos iniciais, bem como os significados atribuídos ao que foi vivenciado no processo educativo durante o estágio de docência para a prática pedagógica enquanto futuras professoras.
A formação do leitor literário a partir da emancipação para Jacques Rancière e da concepção de sociedade do espetáculo de Guy Debord
Authors: Jakabson Lavezzo Lana , Cabral Gladir da Silva
Published: December 2023

Este estudo busca compreender e analisar como a formação do leitor literário ocorre a partir das implicações da sociedade do espetáculo, um conceito de Guy Debord (2003), e da emancipação sob a perspectiva de Jacques Rancière (2019). Ao considerar a importância da leitura literária para a formação dos indivíduos, problematizaram-se algumas situações que poderão ou não contribuir para o desenvolvimento do sujeito leitor. Relacionadas ao conceito de espetáculo, essas situações foram analisadas por meio de pesquisa bibliográfica, qualitativa e reflexiva. Os livros A sociedade do espetáculo, de Debord, e O mestre ignorante, de Rancière, foram a base fundamental para o embasamento teórico, embora outras obras também sejam eventualmente acionadas para complementar análises de pontos específicos. O trabalho aqui realizado revelou que tanto a concepção de “partilha do sensível”, de Jacques Rancière, quanto a de “sociedade do espetáculo”, de Guy Debord, têm grande aplicabilidade para o campo da educação de modo geral e, sobretudo, para a formação do leitor literário especificamente, ainda mais quando se agrega os conceitos de Antonio Candido, que concebe o acesso à literatura como direito humano e não como privilégio de certas classes sociais. O professor emancipado e consciente dos meandros da sociedade do espetáculo colabora para a formação de leitores emancipados.
Play Types, Design Principles and Participation in Play
Authors: Jensen Jens-Ole , Jørgensen Hanne Hede , Sand Anne-Lene , Hansen Janne Hedegaard , Lieberoth Andreas , Skovbjerg Helle Marie
Published: December 2023

Many school-age children have difficulties participating in play and need support to find playmates, take the initiative and structure play. If children do not master these competencies, they risk ending up in a spiral in which they are not given the opportunity to practice playing and develop play competencies. The purpose of the present study is to investigate how design principles in three different play types can be formulated in order to support pedagogues (educators) in developing new play activities with significant potential for participation. In addition, how these design principles cover more general and generic principles are scrutinized.

This paper is based on a three-year design-based research study in two Danish schools investigating three play types: creative play, role play and movement play. It also presents four design principles on each play type which were found to support the development of new play activities with inclusive potential. As a theoretical contribution, the design principles of each play type are meta-analysed with the goal of helping pedagogues generate play activities with different participation possibilities. The generic design principles are the essence of play, play practices, play materials and play opportunities for participation.
A terhességi intrahepaticus cholestasis gyakorisága és szövődése gestatiós cukorbetegséggel egy hazai városi lakosságban
Authors: Ozsvári-Vidákovich Magdolna , Fekete János Tibor , Szakony Szilvia , Theisz János , Gasparics Roland , Körmendy Miklós , Ádám Zsolt , Sziller István
Published: December 2023

Bevezetés: A terhességi intrahepaticus cholestasis a várandósság
alatt előforduló leggyakoribb májbetegség, amelyre viszketés, a májenzimek és a
szérum-összepesavszint emelkedése jellemző. A betegség jelentősen emeli az
újszülöttkori morbiditást és mortalitást. Célkitűzés: Célunk a
terhességi cholestasis élveszülésekhez viszonyított hazai gyakoriságának és a
terhesség alatt kialakuló kórképekkel mutatott összefügésének elemzése volt.
Módszerek: Szakambulanciánkon 2019. január 1. és 2021.
június 30. között olyan várandósoknál vizsgáltuk az intrahepaticus terhességi
cholestasis előfordulását, akik viszketés miatt jelentkeztek vizsgálatra, és a
szülésük osztályunkon történt. A betegségek diagnózisát a nemzetközi definíciók
alapján állítottuk fel. Az epepangás és a terhességi kórképek kapcsolatát
becsült részvételi valószínűség szerinti párosítással (propensity score
matching) elemeztük. Eredmények: A vizsgált
időszakban osztályunkon összesen 5827 várandós szült; közülük 105 (1,8%) esetben
állapítottunk meg a terhesség alatt kialakult viszketést, amelyet 88 (1,5%)
esetben a májenzimek emelkedése, 17 (0,3%) esetben pedig ezeken kívül a szérum
összepesavszintjének emelkedése is kísért. A terhességi viszketés és a
terhességi epepangás nem jelzett kapcsolatot az anyai életkorral, a korábbi
terhességek és szülések számával, és nem mutatott szezonalitást. A betegséggel
kezelt várandósokban szignifikánsan nagyobb volt a gestatiós diabetes
gyakorisága (16,2%), mint a teljes szülészeti populációban (8,3%), valamint az
illesztett kontrollcsoportban (6,7%) (p<0,05, illetve p<0,05). A
terhességi epepangás nem mutatott kapcsolatot a terhességi magas vérnyomás
különböző formáival, a méhen belüli növekedés elmaradásával és a macrosomiával
sem. Következtetés: Adataink alapján a terhességi epepangás
hazai prevalenciája megegyezik az európai gyakorisággal, és szoros kapcsolatot
mutat a gestatiós cukorbetegséggel. Orv Hetil. 2023; 164(50): 1985–1992.
A káliumkompetitív savgátlók szerepe a felső emésztőtraktus savfüggő betegségeinek kezelésében
Authors: Buzás György Miklós
Published: December 2023

A káliumkompetitív savgátlók a fali sejtekben lévő protonpumpán a kálium- és
hidrogénionok cseréjét gátolják, ezáltal a protonpumpagátlóknál erősebben
csökkentik a savtermelést. A kelet-ázsiai országokban szintetizált vegyületekből
három került kereskedelmi forgalomba. A vonoprazan és a tegoprazan hatásosabb a
gastrooesophagealis reflux kezelésére, mint a protonpumpagátlók. A peptikus
fekély gyógyításában a vonoprazan és a tegoprazan egyenértékű a lanzoprazollal.
A Helicobacter pylori eradikációs kezelésében kelet-ázsiai
tanulmányok szerint a vonoprazan és a tegoprazan hatásosabb, mint a
protonpumpa-alapú hármas kezelések, ezt azonban a közös észak-amerikai–európai
tanulmányban csak részben sikerült igazolni. A káliumkompetitív savgátlók
helyének megítélésére több országra/kontinensre kiterjedő randomizált
tanulmányok szükségesek. Orv Hetil. 2023; 164(50): 1967–1973.
Application of tissue engineering in paediatric
Authors: Botía Martínez C. , Fernández Valadés R. , Alaminos Mingorance M.
Published: December 2023

The aim of this work is to review the current state of the use of tissue engineering in the field of pediatric surgery.
We conducted a search of articles in PubMed under the terms of “Pediatric Surgery AND Tissue Engineering”. All those articles that included in the name of the journal and / or of the article any of the following terms were selected: “bioengineered”, “engineering”, “pediatric”, “children” “pediatric surgery”; In addition to those articles resulting from this same search, which, in our opinion, should be included in our review because they also deal with issues related to tissue engineering applied to disciplines that are part of the daily healthcare task of a pediatric surgeon. 178 articles were obtained. After carrying out a first review, we eliminated those referring to the applications of tissue engineering in cardiovascular surgery, traumatology, dentistry, and otorhinolaryngology, as they are specialties not included within pediatric surgery in our setting. Finally, 117 articles distributed as follows were reviewed: 36 on the area of ​​general surgery (6 bibliographic reviews, 30 experimental), 26 plastic surgery (3 clinical trials, 15 experimental, 8 bibliographic reviews), 33 urology (26 experimental, 7 bibliographic reviews), 22 cleft palate (1 clinical trial, 13 experimental, 8 bibliographic reviews).
There are many works related to tissue engineering and its application to pediatric surgery and, although in the theoretical panorama tissue engineering promises to be a hopeful therapeutic alternative in many pathologies included within this specialty, and although there are multiple experimental studies that suggest a hopeful application in the clinic, there are few works that deal with its real application in pediatric patients.
Past and present of COVID-19 treatment
Authors: Quintanilla Carrillo B. , López Zúñiga M.A. , López Ruz M.A.
Published: December 2023

Since the onset of the COVID-19 pandemic in December 2019, many drugs have been proposed and used in an attempt to address this new disease, which has led to constant changes and updates to treatment guidelines and their recommendations. This review sets out what the evolution of COVID-19 treatment has been like throughout the pandemic. To this end, a review of the literature available on Pubmed, MedRxiv and the WHO, NIH and NICE treatment guides was carried out. Based on this information it has been seen that of all the proposed drugs, only corticosteroids, Remdesivir and Tocilizumab have shown some benefit in studies in patients with COVID-19; while Chloroquine, Hydroxychloroquine and Lopinavir/ritonavir, drugs widely used at the outset, have been completely discarded. On the other hand, although Anakinra, Baricitinib and Colchicine have shown a potential benefit in the first studies, there is still no clear evidence of its effectiveness that allows its recommendation as a treatment in this type of patients. As for anticoagulation, there is no evidence to justify the use of therapeutic or intermediate doses in patients hospitalized with COVID-19, so today prophylactic dose administration is recommended.
Measurement of the flux-weighted average cross section for the \(^{186}\)W\((\gamma,p)^{185}\)Ta reaction at the bremsstrahlung end-point energy of 70 MeV
Authors: Do Nguyen Van , Tran Dinh Trong , Kim Tien Thanh , Nguyen Thi Hien , Kim Guinyun , Bui Thi Hoa
Published: December 2023

Abstract. The flux-weighted average cross section for the 186W(γ,p)185Ta reaction induced with 70 MeV bremsstrahlung end-point energy was measured using the activation method in combination with off-line gamma activity measurement. The 27Al(γ,2pn)24Na monitor reaction was used for the determination of the bremsstrahlung flux. The bremsstrahlung photons used to produce the photonuclear reactions were generated from a thin tungsten (W) converter by bombardment with a 70 MeV electron beam. The experimental flux-weighted average cross section is compared with the theoretical prediction, for which the absolute cross section was calculated using the TALYS 1.95 code and the bremsstrahlung spectrum was simulated using the computer program MCNPX. The present experiment was carried out at the 100 MeV electron linac of the Pohang Accelerator Laboratory, POSTECH, Pohang, Korea.
L’influence de la culture de Wadowice de l’entre-deux-guerres sur la formation de la personnalité de Karol Wojtyła dans les années 1920–1938
Authors: Graff Tomasz
Published: December 2023

L’article présente le contexte culturel et social de l’entre-deux-guerres à Wadowice, une petite ville du sud de la Pologne, où est né Karol Wojtyła, le futur pape saint Jean-Paul II le Grand. L’objectif de l’auteur est de montrer l’influence du milieu familial, de la communauté paroissiale locale et de l’école sur la formation de la personnalité du jeune Wojtyła. L’auteur a cherché à démontrer que le jeune élève des écoles de Wadowice percevait l’héritage de la culture polonaise comme une partie importante de la culture européenne. Le futur pape s’est familiarisé avec cet héritage en approfondissant systématiquement sa connaissance de l’histoire et de la littérature polonaises, et en particulier des œuvres des romantiques polonais. Jeune poète, acteur et metteur en scène en herbe, il considérait que la culture polonaise avait une mission messianique par rapport à l’ensemble de l’Europe, mais uniquement sur la base des valeurs chrétiennes. Wojtyła, élève du prestigieux lycée néoclassique M. Wadowita et ami des Juifs locaux, s’est également familiarisé avec les œuvres les plus importantes de la littérature européenne, entre autres Shakespeare, a appris l’allemand, le latin et le grec classique, ainsi qu’avec les œuvres des plus grands classiques de la littérature antique. Le climat intellectuel de sa ville natale a certainement eu un impact significatif sur sa perception ultérieure du dialogue international et de l’intégration européenne.
L’enseignement de Jean-Paul II et son rôle dans le processus d’intégration européenne
Authors: Borutka Tadeusz
Published: December 2023

Jean-Paul II a prêché la nécessité de la solidarité interpersonnelle et de l’intégration. Il a appelé à l’abandon de la méfiance, de la rivalité et de la haine mutuelles et à l’édification d’une civilisation fondée sur des relations internationales pacifiques. Il a montré aux Européens une vision de l’unité dans la diversité, la fidélité aux racines chrétiennes, la liberté et la vérité. Selon le Saint-Père, l’histoire de l’Europe demeure liée au christianisme. Bien que la culture européenne soit issue de la civilisation gréco-romaine et qu’elle ait été influencée par le judaïsme et l’islam, elle a été particulièrement marquée par le christianisme, qui a défini le caractère spécifique du continent pendant deux mille ans. Il n’est pas permis de nier cet héritage aujourd’hui. La dimension transcendantale que possède tout être humain ne peut pas non plus être ignorée. Par son enseignement et son engagement, Jean-Paul II est devenu l’un des principaux architectes de l’intégration européenne.
Język polemiki bp. Grzegorza Chomyszyna z bp. Andrzejem Szeptyckim wobec nacjonalizmu
Authors: Derdziak Liubov
Published: December 2023

The article focuses on the language used in the polemic of Bishop Chomyszyn with Bishop Szeptycki on the subject of nationalism, especially Ukrainian nationalism. We found that the metropolitan of Lvov in his statements about this phenomenon used a rather abstract language. His wording was vague and did not specifically match the social situation at the time. He limited himself to general ideas, such as reminding his listeners of universal moral and religious principles, and this kind of approach was met with the nationalists’ approval. On the other hand, Bishop Stanisławowski’s language was clear, unambiguous, clearly defining the evil connected with nationalism. He simply and specifically called all the behavior accompanying this phenomenon, which was clearly contrary to Catholic morality and faith, thus exposing himself to clear resentment and verbal aggression on the part of his opponents. The article also contains some important information about biographical data of both debaters and some characteristic features of their personalities, the history of Ukrainian nationalism and Szeptycki’s, Chomyszyn’s and other Greek Catholic bishops’ reactions to the phenomenon— based on three groups of source documents.
Mowa nienawiści w czasie pandemii
Authors: Nawara Dariusz
Published: December 2023

Hate Speech during the COVID-19 pandemic was primarily experienced by healthcare professionals, patients who had been diagnosed with SARS Cov-2 infection and police officers. Moreover, reports indicate that xenophobic, racist and anti-Semitic attitudes and verbal attacks had suddenly intensified. They seem to have been connected with blaming certain social and ethnic groups for spreading the virus. The language used in media space, for example conversations and interviews, was often full of vulgarity, and aggression, which sometimes led to destruction of private property as well as physical violence. There was clearly a general lack of calm, reflection, kindness and appeal to reliable sources, and no attempt to correct certain stereotypes, myths and errors as well as showing at least some empathy for the suffering, which could have been an antidote for hate speech, not only during pandemic but also in post-pandemic times.
Book Review: Public Space: Notes on Why it Matters, What We Should Know, and How to Realize its Potential
Authors: Crawford Pat
Published: December 2023

In this book review, Dr. Pat Crawford will discuss Vikas Mehta’s new book, Public Space: Notes on Why it Matters, What We Should Know, and How to Realize its Potential. Dr. Mehta approaches public space from a deep disciplinary grounding in planning, urban design, sociology and architecture, and his new book captures the diverse disciplinary ways of understanding and knowing public space.