bluuebunny/crossref_metadata_2025 huggingface dataset:
CORRELATION OF POINCARE PLOT DERIVED STRESS SCORE AND HEART RATE VARIABILITY PARAMETERS IN THE ASSESSMENT OF CORONARY ARTERY DISEASE
Authors: Kumar Rahul , Aggarwal Yogender , Nigam Vinod Kumar , Sinha Rakesh Kumar
Published: January 2024

Atherosclerosis-generated coronary artery disease (CAD) causes the anomaly of autonomic activity. The assessment of autonomic balance under disease conditions is of clinical interest. Thus, this work aimed to evaluate the CAD using Poincare-derived stress score (SS) and sympathetic/sympathetic-parasympathetic (S/PS). A total of 60 male (50–55 years) volunteers including CAD ([Formula: see text]=30) and control ([Formula: see text]=30) participated in this work. Digital lead-II electrocardiogram (ECG) was recorded for 10 min in a supine position and filtered to remove noises. A total of 10 tachogram samples were computed from each subject for a 5 min ECG signal duration with a shift of 30 s on the processed signal using Acqknowledge 4.0 (Biopac Systems Inc., USA). The heart rate variability (HRV) parameters were computed from the obtained tachogram. The computed Poincare plot parameters were used to derive the SS and S/PS ratios. The regression model was employed to observe the correlation of SS and S/PS to the HRV parameters. The obtained results revealed reduced HRV with higher sympathetic and reduced parasympathetic activity under CAD than the control subjects. The autonomic dysfunction was observed with significantly higher values of SS and S/PS in CAD than in the control subjects. The S/PS was observed to be positively associated with LF/HF and SD2/SD1 parameters. While SS was found to be positively correlated to the LF and LF/HF parameters in CAD and control subjects. The obtained linear strong correlation of SS and S/PS with control and CAD subjects suggested the use of SS and S/PS as excellent sympathetic activity and sympathovagal balance markers.
Insights into New Trends and Contemporary Challenges in 3D Printing in Architectural Sector
Authors: Di Salvo Santina
Published: January 2024

This chapter explores the most recent trends and challenges stemming from the integration of 3D printing within the architectural sector. The rapid evolution of additive manufacturing has brought forth innovative design possibilities, parametric modeling and sustainable material exploration. The discussion provides insights into available 3D printing technologies and methodologies for fabricating architectural products or designs, along with the advantages and challenges that must be addressed to get maximum benefits. To achieve this goal, case studies and current research are examined, with a specific focus on ongoing issues related to housing and environmental needs. Through an analysis of these developments, this contribution highlights the dynamic landscape where technology and architecture intersect, underscoring the necessity of collaborative approaches to fully realize the continuously improving and more sustainable efficiency of 3D printing in shaping the future of the construction field.
The Art of Timing: Unpacking the Market Timing's Long -Term Impact on Capital Structure : With Reference to Listed Companies in Colombo Stock Exchange
Authors: Mudalige H. M. N. K.
Published: January 2024

The market timing theory serves as the basis for this study, which aims to unravel the persistent reaction to capital structure decisions. The rationale for conducting this study stemmed from observing a gap in understanding the capital structure behaviour of firms surrounding their initial public offerings and the progression of debt and equity from that initial point. The study's sample, which covered the years 1992 to 2018, was created by using the IPO date of companies listed at the Colombo Stock Exchange) in Sri Lanka. To measure market timing, the study utilized a variable called external finance weighted average market-to-book ratio. This variable served as an indicator of the firms' timing decisions in relation to the capital structure. A panel regression model quantified the timing impact, showing an inverse association between variables. However, the strength of the correlation was found to be less significant than what market timing theory had predicted. Thus, it could not be proven that listed companies consistently increase their equity by issuing new shares when the current share price rises. These findings suggest that while market timing may have some influence on the determination of the debt and equity portions in capital structure decisions, other factors may also come into play. The study highlights the importance of considering additional variables and factors that can impact capital structure choices. It further emphasizes the significance of increasing equity on firm capital structures and costs, and suggests that management can potentially adjust the capital structure based on historical market-to-book ratios.
A multilevel analysis of individual, household and community level predictors of child diarrhea in Eswatini
Authors: Simelane Maswati , Vermaak Kerry
Published: January 2024

The aim of the study was to investigate the effect of individual, household and community level factors on child diarrhea. The study used a pooled secondary data analysis approach from the 2010 and 2014 Eswatini Multiple Indicator Cluster Survey (MICS). Multilevel logistic regression was used for data analysis. Compared to children aged under 6 months, the odds of having diarrhea were higher for children aged 6-11 months, adjusted odds ratio, AOR 5.34(95% Confidence interval):2.39-11.90) and 12-23 months AOR. 3.90 (1.76-8.64).  Reduced odds of diarrhea were observed among children with a normal height for age (AOR0.09(0.01-0.93) and above normal height for age (AOR: 0.07 (0.01-0.85) compared to those with a growth deficit. Children from households with no toilet facility at all had 283% increased risk of having diarrhea compared to those with flush toilets. Regionally, the risk was higher in the Hhohho region (AOR2.59 (1.08-2.65), reference: Lubombo region. Higher odds were observed among communities with a higher and medium proportion of diarrhea AOR9.77(4.59-20.80), AOR 3.60 (2.26-6.20) respectively, compared to communities with a low proportion of diarrhea
Immunisation services in North‑Eastern Nigeria: Perspectives of critical stakeholders to improve uptake and service delivery
Authors: Omoleke Semeeh A. , Omotara Babatunji A. , Oyeyemi Adewale L. , Beida Omeiza , Etatuvie Samuel O.
Published: January 2024

We investigated the perspectives of parents, health workers (HWs) and traditional medical practitioners (TMPs) on immunisation advocacy, knowledge, attitudes and immuni‑ sation practice and ways of improving immunisation uptake in Borno State, North‑eastern Nigeria. A cross‑sectional study analysing quantitative data from the three stakeholders' categories. It was conducted across 18 local government areas of Borno State. A representative sample of 4288 stakeholders (n=1763 parents, n=1707 TMPs, and n=818 HWs aged 20 to 59years, had complete data. The sample has more males: 57.8% (Parents); 71.8% (TMPs) and 57.3% (HWs). The awareness of immunisation schedule among the stakeholders ranged from 87.2 to 93.4%. The study showed that 67.9% of the parent and 57.1% of the health workers had participated in immunisation except the TMPs (27.8%). Across the stake‑ holders' categories, between 61.9 and 72.6% have children who had Adverse Event Following Immunisation (AEFI). The most common AEFI was fever. Safety concerns, preference for herbs and charm, culture and religions, and vaccination perception as a western culture were the major barriers to immunisation uptake. While 63.6 to 95.7% of respondents indicated that community leaders, religious and spiritual leaders and TMPs should be involved in immunisation advo‑ cacy, 56.9‑70.4% of them reported that community leaders should be involved in immunisation policy. Upscaling the critical stakeholders' involvement in advocacy, policy devel‑ opment and implementation of immunization activities may improve acceptance, create demand and engender ownership in vulnerable communities of Borno State, Nigeria. AEFI could be detrimental to immunisation access and utilization. Consequently, health education by health workers needs strengthening to minimise vaccine hesitancy.
Nutrition education has significant impact on perceived barriers to healthy diet among adults with and without COVID‑19 history
Authors: Dewi Risti K. , Mahmudiono Trias , Yuniar Cindra T. , Mahmudiono Trias , Zebadia Eurika , Sahila Nur , Wijanarko Mutiara A.V. , Haliman Chika D. , Adrianus Rahmania , Tang Shirley G.T.
Published: January 2024

Healthy diet is an important tool to lower the risk and severity of COVID‑19 infection. Low diet quality is usually caused by perceived barriers that stop people to do certain behavior. Perceived barriers can be overcome by imple‑menting proper method such as conducting nutrition education. This study aimed to analyze the impact of nutrition education on perceived barrier to healthy diet among adults with and without covid‑19 history in Padang, Indonesia. This study was a pre‑experimental study using pre and post‑design. This study was conducted on 70 adults with or without COVID‑19 infection history, residing in Padang, Indonesia. The intervention was given in the form of nutrition education. Difference test was conducted to assess the impact of nutrition education on respondents' nutrition knowledge and perceived barriers. The majority of the respondents both with and without COVID‑19 history (71.4 and 80%) had medium level of nutritional knowledge before the intervention. After the intervention, there was a significant (P0.05) improvement on respondents' nutritional knowledge for both groups (100%). The result also showed 40% of the respondents with COVID‑19 history had medium level of perceived barriers, while 28.6% respondents without COVID‑19 history (65.7%) had medium level of perceived barriers before the intervention. A significant improvement (P0.05) also showed on respondents' perceived barriers after the intervention. On both groups more 90% of the respondents only had low level of perceived barriers. The result shows that nutrition education has significant impact both on respondents' nutritional knowledge and perceived barriers.
Nigeria Centre for Disease Control awareness creation and risk communication of Covid-19 pandemic amongst non-literate population in south-west Nigeria: lessons for future health campaign
Authors: Ojeka-John Rachael , Sanusi Bernice O. , Adelabu Omowale T. , Oyekola Isaac A. , Ajakaiye Olanrewaju O. P. , Ejem Agwu , Talabi Felix O.
Published: January 2024

Background: Risk communication of Covid-19 pandemic in Nigeria appeared to be urban-centred with the dominant use of social media, print communication and other controlled media. In such times of public health emergencies, non-literate population could be vulnerable as a result of their limited understanding of the nature of such health risk.
Objective: Therefore, the study seeks to investigate the extent to which NCDC communicated the risk of Covid-19 disease to non-literates population in its public health campaign during the pandemic in South-West Nigeria.
Methods: The study adopts risk communication theory which advances the approach communication should take during public health emergencies. Using the concurrent mixed method research design, a sample of 420 respondents were purposively selected from 6 towns in the rural areas of Lagos, Oyo and Osun states to examine the level of awareness on Covid-19 pandemic among non-literates. In addition, NCDC risk communication on Covid-19 for non-literates population were analysed from 3 Jingles in Yoruba language as well as 9 flyers designed for Covid-19 disease from NCDC websites.
Results: Results showed that NCDC awareness creation on Covid-19 disease for non-literates in Southwest achieved significant success as a result of the medium used in creating awareness. Specifically, radio was highly rated among majority of the respondents (60.4%) followed by Health workers (19.8%) as channels that created understandable message on Covid-19 safety protocols. Further findings on Jingles content revealed that all Covid-19 safety protocols were communicated in Yoruba language for Southwest populace. However, NCDC fall short in communicating Covid-19 risk effectively for non-literates in Southwest as jingles only buttressed the Covid-19 safety protocols and symptoms as well as the need to comply, without educating the masses on the dreadful nature of the disease and its dynamics. Though flyers designed by the NCDC communicated risk to an extent, nevertheless, graphics and symbols on Covid-19 disease were complimented by words in English language only, which could be difficult for non-literates to decipher.
Conclusion: Based on the findings, the study recommends that public health agencies need to educate non-literate population about the nature of a disease more than creating awareness about the outbreak of a disease.
Assessment of Midline Shift in Postdecompressive Craniectomy Patients in Neurocritical Care
Authors: Maramattom Boby V. , Abraham Mathew , Sundararajan Ananthram
Published: January 2024

Background:

Monitoring and evaluation of intracranial structures remain a fundamental element in the neurointensive care unit. Most used technique to monitor progression is the use of computed tomography (CT) in intracranial hemorrhage (ICH) or stroke. Rapid assessment of brain pathology can be made using CT to analyze the midline shift (MLS), hematoma expansion, and ventricular size, but transferring a patient who is intubated is time and resource-consuming task. Ultrasonography is a noninvasive technique, portable, and has the possibility of fast interpretation.

Aims and Objectives:

To measure the brain MLS in decompressive craniectomy patients using transcranial ultrasonography (TCS) and compare the correlation of these results with CT scan measurements of MLS in the same patient.

Materials and Methods:

Patients who have undergone decompressive craniectomy due to various reasons like ICH, traumatic brain injury, etc., and have a MLS. Trans cranial ultrasonography was assessed by a single consultant (Neuro Critical Care Intensivist) who was blinded for the CT scan measurement. CT scan measurement of MLS was assessed by a neuroradiologist using standard guidelines, who was blinded for the TCS results of MLS. The finding of a MLS >0.5 cm in the CT scan was considered a significant MLS.

Results:

A total of 31 patients were recruited for the study. MLS measured using CT was 0.91 ± 0.67 cm. MLS via TCS was 0.91 ± 0.66 cm. A significant MLS via TCS was found in 77.4%. Intraclass correlation coefficient (ICC) was calculated between CT-MLS and TCS MLS and obtained the value of ICC as 0.996, indicating an almost perfect agreement.

Conclusion:

Patients after decompressive craniectomy may present as an ideal candidate to visualize intracerebral anatomy with a high resolution. TCS might be considered as an alternative to CT to measure MLS in decompressive craniectomy patients.
Need to Incorporate Endovascular Neurosurgery in Neurosurgery Curriculum in India
Authors: Goyal Nishant , Patil Aditya Kiran , Kuldeep Robi , Rajpal Girish
Published: January 2024

Endovascular neurosurgery is one of the most rapidly evolving subspecialties in the field of neurosurgery. Since its inception, it has taken up almost 50%–60% of the cerebrovascular workload. Various specialties are competing to claim this field; still, no one can argue against a neurosurgeon's suitability in performing endovascular techniques. Currently, the field is shared between neurosurgeons and neuroradiologists, each getting different pie shares in various parts of the world. However, in India, barring a few residency programs, most neurosurgery programs offer little or no exposure to endovascular techniques. There is an urgent need for endovascular neurosurgery to be incorporated in the neurosurgery training curriculum in the country. Performing DSAs is the first step toward starting an endovascular neurosurgery unit. We have presented here the data of the DSAs done by a single neurosurgeon over almost 3 years. We have discussed our experience in the hope that fellow neurosurgeons across the country find it useful.
Measurement of Neutrophil Gelatinase-Associated Lipocalin (Ngal) Following Neuroradiological Procedure/s in Patients with Aneurysmal Subarachnoid Hemorrhage
Authors: Kaushal Ashutosh , Chouhan Rajendra S , Bindra Ashish , Gaikwad Shailesh , Subbiah Vivekanandhan
Published: January 2024

Background:

Radiocontrast administration during interventional neuroradiology (INR) procedures for aneurysmal subarachnoid haemorrhage (aSAH) can add to renal insult. Serum creatinine (sCr) is a conventional marker of acute kidney injury (AKI). Serum neutrophil gelatinase-associated lipocalin (sNGAL) is a novel marker which is increasingly used to predict renal injury in susceptible patients.

Objectives:

The primary aim of this study was to evaluate correlation between serum neutrophil gelatinase-associated lipocalin (NGAL) and sCr in aSAH patients undergoing therapeutic or diagnostic INR procedures. The secondary aim was to find the incidence of contrast-induced AKI and hemodynamic complications during the study period.

Material and Methods:

All consenting aSAH patients (18–60 years, Modified Hunt and Hess grade 1–4) posted for INR procedures during the study time were included. Patients with history of chronic renal disease, recent contrast exposure, or renal insufficiency were excluded. Blood samples for sCr and sNGAL were obtained preprocedure and then at 1, 6, 24, and 48 h after contrast administration. Hourly urine output was noted. AKI was defined by KDIGO guidelines.

Statistical Analysis Used:

Repeated measurement analysis of variance, Posthoc Bonferroni test and Pearson correlation coefficient test.

Results:

Fifty patients, mean age 47.34 ± 9.31 years, were enrolled for the study. Majority (48; 96%) were Hunt and Hess (H and H) grade I–III. The mean volume of contrast administered was 123.2 ± 53.08 mL. The mean sNGAL and sCr values at pre-op, 1, 6, 24, and 48 h were 124.99 ± 64.58, 148.40 ± 77.90, 147.33 ± 76.00, 125.49 ± 64.44, and 116.38 ± 61.79 ng/mL and 0.629 ± 0.23, 0.624 ± 0.22, 0.612 ± 0.21, 0.632 ± 0.19, and 0.577 ± 0.22 mg/dL, respectively. There was a correlation in sCr and sNGAL value (P < 0.001) at all study time points. However, no specific pattern was seen. No patient developed any AKI or hemodynamic complications in first 48 h.

Conclusions:

There is a correlation between serum NGAL and sCr at individual time points. NGAL may represent a sensitive early biomarker of renal impairment after INR Procedures. There was no incidence of AKI after contrast administration in aSAH patients without predisposing renal risk factors.
Glutathione gel-encapsulated niosomal delivery system versus glutathione gel only in treatment of melasma: a comparative study
Authors: Abdel-Azim Eman S. , Aly Usama F. , Dakhly Heba O. , Montaser Mahmoud H.A.
Published: January 2024

Background

Glutathione is an antioxidant agent used in the treatment of melasma. However, niosome is a drug delivery enhancer used in other skin diseases to increase the absorption of any active ingredient.

Objective

To assess the efficacy of niosome with topical glutathione gel 2% in the treatment of melasma versus topical glutathione gel 2% alone.

Patients and methods

In this comparative study, 19 patients complaining of melasma were divided into two groups. Group 1 was treated with glutathione gel 2% only, while group 2 was treated with glutathione gel 2% encapsulated in niosome. The split face method was used where right side of face for treatment and left side for placebo. Patients were photographed and examined clinically by Wood’s light and dermoscopy. All patients were evaluated clinically using a modified Hemi-Melasma Area and Severity Index (HEMI-MASI) score with the calculation of the reduction percentage and grading of the improvement. Moreover, histopathological examination was done before and after treatment.

Results

In Glutathione treated right side, hemi-MASI score after treatment was decreased with no significant difference when compared with base line; while in Glutathione gel with niosome treated right side; hemi-MASI score was significantly decreased. There was a high significant difference in reduction percentage of hemi-MASI score of both right sides of face of the two groups. No side effects were reported by patients of both groups. After treatment, both H and E and FM sections showed a decrease in basal hyperpigmentation in the case of epidermal melasma and a decrease in dermal melanophages in mixed melasma in both groups.

Conclusion

Topical glutathione gel alone without niosome is a weak melasma treatment. Niosome enhances glutathione gel absorption and efficacy without any side effects.
Intestinal fatty acid bind protein as a biomarker for vitiligo
Authors: Shaker Olfat G. , El-Tahlawi Samar M. , Fawzy Mina A.
Published: January 2024

Background

Vitiligo is an acquired depigmentary disorder characterized by destruction of melanocytes. The activity of vitiligo influences the clinical outcome and alters the choice of treatment modality. Intestinal fatty acid binding protein (I-FABP), also called FABP-2, is solely expressed in intestinal enterocytes of mammals.

Objective

To evaluate the serum and tissue levels of I-FABP in vitiligo patients and its relation to healthy controls.

Patients and methods

The present study is a case-control study that was carried out on 44 subjects subdivided into two equal groups, vitiligo, and matched controls. The clinical study was done as well and I-FABP levels in both serum and tissue were measured by Enzyme-linked immunosorbent assay (ELISA).

Results

There were significant elevations in I-FABP levels in both serum with a median of 7.16 and 5.29 (P=0.011) and in tissue with a median of 707.3 and 274.9 (P=0.014) for vitiligo patients in comparison with controls, respectively. Positive correlation between I-FABP levels in serum and in tissue was detected (r=0.488, P=0.021). Sensitivity for diagnosis vitiligo for serum and tissue I-FABP were 77.3 and 86.36%, respectively and specificity were 54.5 and 95.5%, respectively.

Conclusion

I-FABP can play a vital role in vitiligo and may be a marker that helps in early diagnosis of vitiligo, but it does not appear to be useful for determining vitiligo activity, severity.
Governance Framework and Public–Private Partnership for Universal Health Coverage: Findings from India’s Federal Health Structure
Authors: Venkatraman A. , Lahariya Chandrakant
Published: January 2024

Background:

The role of private health sector in advancing universal health coverage is being recognised globally. A number of public–private partnership (PPP) strategies have been implemented across the states in India. States are primarily responsible for health service delivery in India.

Objectives:

To summarise various PPP schemes and projects in health sector across the states in India and to understand the ecosystem, i.e. policy, legal and institutional framework that are critical for effectively governing the partnerships.

Materials and Methods:

The study was carried out in two stages: a comprehensive desk review, followed by field visits for in-depth interviews (IDIs) of key stakeholders in selected states. A total of 52 IDIs were conducted from various levels of stakeholders.

Results:

Nearly 250 PPP initiatives in health sector across all Indian states were identified and studied. Partnership with the private sector was predominantly in the areas of emergency transport and laboratory diagnosis and in the delivery of selected primary care services. PPPs in health infrastructure (hospitals and medical colleges) and purchasing arrangements are rapidly emerging across most states. However, only few Indian states have health sector-specific PPP policy or legal and/or institutional framework governing PPPs and organisational units implementing partnership schemes. The capacity to conceive, design, implement and manage PPPs in health sector was found either absent or insufficient in most states.

Conclusion:

There is a need for developing mechanisms for effective and functional partnerships with the PHS for achieving national health policy goals in India. There is a need for well-enunciated policy and governance framework for private sector engagement. Indian union and state governments need to do detailed assessment of the PHS market behaviour; legal, regulatory and oversight mechanisms; building organisational structures with capacities and developing platforms for stakeholder dialogue. Findings from the Indian context could offer useful insights for other low- and middle-income countries aiming to advance towards achieving universal health coverage.
Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
Authors: Lahel Ranjit Singh , Kumar Sangeet , Mishra Rajesh Kumar
Published: January 2024

Skeletal dysplasias form an assorted cluster of bone dysplasias that result in atypical and aberrant skeletal size and shape. The case discussed here was diagnosed as thanatophoric dysplasia during the second-trimester ultrasound examination and the medical termination of pregnancy was subsequently done. The fetus had shortening of the limbs (micromelia) with long bones (shaped like a telephone receiver), a small conical thorax, a protuberant abdomen, increased skin thickness with a cloverleaf skull, and macrocephaly. The relevant details and review of literature pertinent to the case are hereby discussed.
Imaging of Venolymphatic Malformation in a Child Extending from Inguinoscrotal Region to Thoracic Region: Case Report with Review of Literature
Authors: Ansari Mohammad Ameen Abdus Salam , Dhok Avinash Parshuram , Ladke Pooja Giridhar , Shinde Nitin
Published: January 2024

Vascular malformations (VM) are structural malformations of vascular development causing soft-tissue abnormality with functional and esthetic impairment. They are named by their predominant vessel type as arterial, venous, lymphatic, or mixed types. VM extending from the inguinoscrotal to the thoracic region are extremely rare presentation. We present a rare case of veno-lymphatic malformation in the inguinoscrotal region, which is extending superiorly up to the right thorax in a 14-year-old male child who presented with a large swelling in the bilateral inguinoscrotal region and reddish–brown colored skin patches over the right anterior and lateral thoracoabdominal region. The diagnosis was suggested by ultrasonography and confirmed by computed tomography and magnetic resonance imaging.
Can cutaneous sarcoid be a marker for metabolic syndrome? A case illustration
Authors: Monteiro Rochelle Cheryl , Kamath Suvidha D. , Martis Jacintha
Published: January 2024

Sarcoidosis is a multisystem inflammatory disorder involving the organs such as lungs, lymph nodes, and eyes. Cutaneous involvement is seen in 20%–35% of the cases with systemic involvement. We report the case of a 46-year-old female, who presented with multiple skin-colored papules and nodules over the body, with no evidence of systemic involvement. On further investigation she was detected to have diabetes mellitus and metabolic syndrome (MetS). The association of MetS with systemic sarcoidosis has been described in the literature. However, there is no previous reported association of isolated cutaneous sarcoidosis with MetS. In our context, the presence of MetS was an incidental finding. Hence, cutaneous sarcoid should be considered a marker for underlying MetS and all cases of isolated cutaneous sarcoid should be extensively investigated for the same, even in the absence of systemic manifestations. We illustrate this case as this association is hitherto unreported.
Pleural effusion as the presenting feature in chronic myeloid leukemia
Authors: Bhat Archana S. , Nazar Rahma , Mascarenhas Don Gregory , Prasad Krishna , Kulkarni Manjunath Jeevanna
Published: January 2024

Pleural effusion is rarely associated with chronic myeloid leukemia (CML). CML is asymptomatic and incidentally detected in majority of the patients. Few present with symptoms related to splenomegaly. Pleural effusion as the presenting symptom in CML has rarely been reported in the literature. We report the case of 58-year-old woman who presented with pleural effusion. Working diagnosis was lung malignancy or lymphoma. However, investigations and examination revealed CML in blast crisis. The patient was then treated with dasatinib, and she responded well. The exact mechanism for pleural effusion in CML is not known. It could be due to leukemia infiltration, extramedullary hematopoiesis, capillary obstruction, infections, or drug induced. Our case showed features compatible with extramedullary hematopoiesis. CML can rarely present with pleural effusion. Simple tests such as blood smear examination and pleural fluid cytology will aid in the diagnosis. The physicians and pathologists should be aware of this association.
Bacterial profile and antimicrobial resistance in a Tertiary Hospital in Mexico
Authors: Beltran Francisco , Vazquez Romo Kristian A. , Oyervides Alvarado Jose Arturo , Gonzalez Dibildox Laura Alejandra , Betancourt Nallely Ramos , León Manuel Garza , Quintela Everardo Hernandez
Published: January 2024

Objective:

The objective of this study was to report the characteristics and the bacterial microbiological frequency of the etiological agents and the antibiotic sensitivity of the isolated pathogens in infectious keratitis in Mexico between 2012 and 2016.

Methods:

This was a retrospective, cross-sectional, and observational study; medical records of all patients who presented in the cornea department in Mexico with infectious keratitis from 2012 to 2016 were reviewed. Demographic data, Gram stain, and microorganisms obtained in the culture and antibiotic sensitivities were evaluated by disc diffusion test.

Results:

In the studied period, a total of 639 (40.67%) cases that had a positive culture were included; 54.5% were male with an average age of 48.50 ± 20.43. Gram-positive agents were the most frequent with 80.66% of cases. The most frequent causative agent was Staphylococcus epidermidis (36.61%). The most frequent Gram-negative agent was Pseudomonas aeruginosa (7.55%). The antibiotic with the highest sensitivity was netilmicin (90.3%), followed by moxifloxacin (82.3%) and gatifloxacin (81.3%). Among fortified antibiotics, ceftazidime had a sensitivity of 78% while vancomycin 43.8% (for Gram positive).

Conclusion:

Bacteria are the most common cause of infectious keratitis, Staphylococcus and Pseudomonas as the most common isolates. There was low resistance to netilmicin and fourth-generation fluoroquinolones for these isolates.
Corneal perforation in a patient with COVID-19 pneumonia under helmet continuous positive airway pressure ventilation treatment
Authors: Matias Maria João , Ruao Miguel , Costa João , Chibante-Pedro João , Almeida Inês
Published: January 2024

Ocular surface complications secondary to continuous positive airway pressure (CPAP) machines have been previously reported such as ocular irritation, dry eye disease, lid laxity, and floppy eyelid syndrome. No severe ocular complications have been specified in the literature. We report a serious ocular complication in a patient under helmet CPAP (hCPAP). A 68-year-old male with COVID-19 pneumonia required ventilatory support with hCPAP. Following 5 days, the patient started complaining of ocular discomfort, purulent discharge in his left eye, and ocular dryness upon awakening. Ophthalmological examination showed no light perception in the left eye and slit-lamp biomicroscopy revealed atalamia, loss of corneal transparency with superior infiltrates, and a total epithelial defect with iris herniation and a central perforation. Considering the patient's progressive worsening clinical condition, with a painful blind eye, left evisceration was performed. It is important to be aware of possible ophthalmological complications related to ventilation since prompt diagnosis and treatment can avoid poor visual outcomes. In this clinical case, we faced a serious ocular complication following hCPAP ventilation.
Choroidal rupture and macular hole secondary to blunt trauma
Authors: Rezende Catherine Pancini , de Souza Felipe Belucio , Peixoto Beatriz Crotti , Ayres da Fonseca André Luis , de Andrade Sobrinho Marcelo Vicente
Published: January 2024

This is a retrospective case report of a male patient referred to the PUC Campinas Hospital as a victim of blunt car trauma. On ophthalmological examination, the patient had bilateral retinal changes in the foveal region, causing low visual acuity in both eyes. Knowing that ocular trauma is the main cause of legal blindness in working-age people, this study aimed to highlight the importance of ophthalmological evaluation to provide the necessary treatment and follow-up to minimize the ocular sequelae resulting from trauma.
Visual outcome of pediatric ocular trauma in a Latin American population
Authors: Espinosa Natalia , Montoya Luisa , Gaviria Andrés , Solano Adriana
Published: January 2024

Objective:

The aim is to assess associated factors regarding the type of pediatric ocular trauma and final visual acuity (VA) of the patients received ophthalmology service at tertiary care facility between 2013 and 2018.

Methods:

Retrospective cohort study. The clinical history of patients between 0 and 15 years of age diagnosed with ocular trauma was examined. The exposure variable was the type of ocular trauma (open or closed). Other variables related to ocular trauma were studied.

Results:

A total of 183 ocular trauma cases were studied. The median age was 9 years (interquartile range: 5–12), most patients were males (65.5%), blunt and sharp objects were the most frequent causes of ocular trauma (41% and 33.3%, respectively). Closed ocular trauma was found in 82.5% of the cases and zone 1 was the most frequently involved (76,5%). Sixty-four percent of cases required surgical management and 26% presented complications at the final follow-up. About 78.7% of the patients had VA equal or higher than 20/40. The risk factors associated with worse visual outcome (worse than 20/40) was found to be open ocular trauma (relative risk [RR] = 5.5; 95%IC: 3.3–9.2), the affected zone (higher risk in zone 3 with RR = 7.62; 95% confidence interval: 7.61–7.63) and time elapsed between the moment of trauma and receiving ophthalmological treatment (RR = 1.01; 95%IC: 1.01–1.01).

Conclusion:

Most patients that presented with ocular trauma had satisfactory final VA, considering that closed ocular trauma was more frequent. Open ocular trauma, the affected zone, and the time elapsed before starting treatment were associated with worse VA outcomes in our study.
Concordance between Goldmann, Icare Pro®, Corvis ST® and Tonopen® tonometry, and their correlation with corneal thickness
Authors: Mendieta Patricia Hernández , Puerto Mayerly López , Goyeneche Fernando Gómez , Guacaneme Aracelly Charris
Published: January 2024

Introduction:

The objective is to evaluate the concordance of intraocular pressure (IOP) values by comparing three tonometers; Corvis ST (COR), Icare Pro (ICA) and Tonopen (TOP) with the gold standard, the Goldmann applanation tonometry (GAT and the effect of the measurements by the central corneal thickness (CCT).

Methods:

One hundred and eight eyes were selected (59 patients) who underwent IOP measurement with four instruments (Icare, Corvis, Tonopen and Goldmann). An univariate analysis was applied, and then a concordance analysis was performed in which the intraclass correlation coefficient (ICC) was calculated between the different instruments taking into account the corneal thicknesses to eliminate confounding effect in measurements.

Results:

109 eyes (59 patients) were included, 66% women and 34% men. Average age 52.2 years (SD 13.87). Univariate analysis was performed and a mean age 52.2 (SD ± 13.87) and mean IOP were obtained for Goldman 15 (SD ± 2.94), Icare 15 (SD ± 2.47), Tonopen 14 (SD ± 2.85), Corvis 14 (SD ± 2.67).
Ocular cryptococcosis in a HIV-positive patient
Authors: Peixoto Beatriz Crotti , Patrus Bianca Prado , de Souza Felipe Belucio , Rezende Catherine Pancini , Baccega Augusto Terra , de Andrade Sobrinho Marcelo Vicente
Published: January 2024

We report a rare case of ocular cryptococcosis that presents as chorioretinitis in a patient with acquired immunodeficiency syndrome.
Employee Attrition: Analysis of Data Driven Models
Authors: Nandal Manju , Grover Veena , Sahu Divya , Dogra Mahima
Published: January 2024

Companies constantly strive to retain their professional employees to minimize the expenses associated with recruiting and training new staff members. Accurately anticipating whether a particular employee is likely to leave or remain with the company can empower the organization to take proactive measures. Unlike physical systems, human resource challenges cannot be encapsulated by precise scientific or analytical formulas. Consequently, machine learning techniques emerge as the most effective tools for addressing this objective. In this paper, we present a comprehensive approach for predicting employee attrition using machine learning, ensemble techniques, and deep learning, applied to the IBM Watson dataset. We employed a diverse set of classifiers, including Logistic regression classifier, K-nearest neighbour (KNN), Decision Tree, Naïve Bayes, Gradient boosting, AdaBoost, Random Forest, Stacking, XG Boost, “FNN (Feedforward Neural Network)”, and “CNN (Convolutional Neural Network)” on the dataset. Our most successful model, which harnesses a deep learning technique known as FNN, achieved superior predictive performance with highest Accuracy, recall and F1-score of 97.5%, 83.93% and 91.26%.
CBT techniques for male delayed ejaculation. A case study
Authors: Rawi Srouji
Published: January 2024

Delayed ejaculation (DE) is a rare and poorly defined form of male sexual dysfunction. It is probably the least researched sexual disorder due to its low prevalence rates, affecting 1-4% of men. Individuals with this condition suffer from difficulty or inability to reach ejaculation latency and diminished control. Consequently, patients and their partners experience lower sexual satisfaction, affecting their overall relationship satisfaction negatively. The current case study is aimed at providing a comprehensive overview of the current knowledge on the definition and explanations of male delayed ejaculation. Additionally, to investigate the efficacy of CBT techniques on men with (DE). Findings indicate that ejaculation control is negatively correlated with sexual performance and positively correlated with relationship intimacy. Following CBT sessions on a weekly basis, reduction of performance anxiety in subject 1 contributed in ejaculation control enhancement of (170%) and (200%) at post-intervention and follow-up. Whereas, promoting relationship intimacy in subject 2 lead to a growth of (146%) and (230%) at similar evaluation assessment. The relevance of this outcome is providing a significant relevance to CBT techniques in treating (DE) and avoiding the development of other psychological or sexual disorders. For future research, we suggest including a larger sample size in order to improve the study’s statistical power, strengthen scores’ accuracy and reduce the likelihood of possible errors.
Amanda Labarca y la recepción temprana de su obra literaria en Chile
Authors: Salas Gonzalo
Published: January 2024

El presente artículo es una revisión de más de una veintena de libros de literatura, crítica literaria, historia de la literatura y otras temáticas asociadas, publicadas en Chile para relevar la primera recepción de la obra de Amanda Labarca en el campo de la literatura, antes de su fallecimiento en 1975. El artículo se divide principalmente en dos secciones, la primera relacionada con autores que la consideran, sea mediante una crítica positiva o negativa y en segundo lugar, una crítica que la invisibiliza. Si bien existieron más autores que la invisibilizan versus los que la consideran, es importante tener en cuenta que Labarca también fue conocida en vida por su trabajo literario en los diversos géneros que publicó (novela, cuento, ensayo y crítica). La segunda recepción está en pleno desarrollo y dará mucho que hablar de esta importante autora cuyo ideario sigue por descubrirse.
İlkokul Öğretmenlerinin Öğretim Sürecindeki Yüksek Zaman Yönetimi Beceri Düzeylerine İlişkin Görüşlerinin İncelenmesi
Authors: Gelen Tevfik , Yaşar Mehmet
Published: January 2024

Öğretim sürecindeki zamanın sınırlılığı, öğrenciler arasındaki bireysel öğrenme farklılıkları, tamamlanması gereken öğretim programı, öğretim dışı sayılabilecek olumsuz öğrenci davranışları ve akademik olmayan yaşantılar, öğretmenin öğretim sürecindeki zamanı iyi yönetebilmesinde karşılaştığı güçlüklerden bazılarıdır. Bu nedenle öğretim sürecindeki zamanın kullanımı ve yönetimi konusu; öğretmenlerin görevlerini daha etkin bir şekilde yapabilmesinde, nitelikli bir öğretim ortamının oluşturulmasında ve akademik başarıların sağlanmasında itici bir güç olarak görülmektedir. Öğretmenlerin bu zamanı bilinçli ve etkili kullanımıyla öğrencilerin daha fazla öğrenme fırsatları yakalayabileceği öne sürülmektedir. Bu nedenle çalışmanın amacı, ilkokul öğretmenlerinin öğretim sürecindeki yüksek zaman yönetimi beceri düzeylerinin nedenlerini öğretmen görüşlerine dayalı olarak ortaya çıkarmaktır. Araştırma, nitel araştırma yöntemlerinden durum çalışması (case study) deseniyle gerçekleştirilmiştir. Araştırmanın çalışma grubunu Kahramanmaraş’ın Türkoğlu ilçesine bağlı ilkokullarda görev yapan ve amaçlı örneklem yöntemiyle seçilen zaman yönetimi beceri düzeyi yüksek öğretmenler oluşturmaktadır. Verilerin toplanmasında araştırmacılar tarafından hazırlanan demografik bilgi ve yarı yapılandırılmış görüşme formu kullanılmıştır. Veriler nitel araştırma yöntemlerinden betimsel analiz tekniği ile çözümlenmiştir. Analizlerden ilkokul öğretmenlerinin öğretim sürecinde zaman yönetimi beceri düzeylerinin yüksekliğinin; ‘’dersten önce’’, ‘’derste’’, ‘’zaman tuzaklarına karşı’’ ve ‘’zamanın etkili kullanılmasına ilişkin diğer faktörler’’ olmak üzere dört ana tema kapsamında yaptıkları başarılı çalışmalarıyla açıklanabileceği sonucuna ulaşılmıştır. Ayrıca, öğretmenlerin öğretim sürecindeki zaman yönetimi beceri düzeylerinin yüksekliğinde, “zamana ve mesleğe karşı pozitif tutumlarının, sınıf yönetimi becerilerinin ve meslekteki kıdem”in öne çıkan faktörler olduğu belirlenmiştir. Araştırmadan elde edilen bulgular ilgili alanyazın temelinde tartışılmış ve araştırmacılara, uygulayıcılara ve politika yapıcılara çeşitli önerilerde bulunulmuştur.
2023 Yılı Deprem Döneminde Yükseköğretim Kurumlarına Giriş Sınavları Kimya Testi Alan Sorularının Kazanımlar Açısından Değerlendirilmesi Ve Covid-19 Pandemi Döneminde Uygulanan Sınav Soruları ile Karşılaştırılması
Authors: Sarıkaya Gacanoğlu Şengül , Nakiboğlu Canan
Published: January 2024

2019 yılında bütün dünyayı etkisi altına alan pandemi sürecinde bütün ülkeler kendi eğitim sisteminde ve merkezi sistem sınav uygulamalarında öğrenim gören bireylerin yararına olacak bir takım önlemler almışlardır. Türkiyede de Covid-19 pandemi sürecine yönelik Yükseköğretim kurumlarına giriş sınavına (YKS) esas kazanımlara Milli Eğitim Bakanlığı tarafından sınırlama getirilmiştir. 2023 yılında ise Türkiye’de 10 ili etkisine alan bir deprem felaketi yaşanmış ve toplumsal açıdan yaygın etkisi olan birçok önlemin alınması gerekli olmuştur. Bu nedenle pandemi sürecinde olduğu gibi Yükseköğretim kurumlarına giriş sınavlarına esas kazanımlar açısından Milli Eğitim Bakanlığı tarafından sınırlamalar yapılmıştır. Bu noktadan hareketle bu çalışmada YKS-2023 Temel Yeterlilik (TYT) ve Alan Yeterlilik (AYT) sınavları Kimya testi sorularının ilgili olduğu kazanımlar bağlamında kapsam geçerliği değerlendirilmiş ve YKS-2020 Temel Yeterlilik (TYT) ve Alan Yeterlilik sınavı (AYT) oturumlarında yer alan Kimya testi soruları ile karşılaştırması yapılmıştır. Çalışmanın sonunda pandemi ve deprem sürecinde YKS sınavlarına esas kazanımlara getirilen sınırlamalarda Kimya testi kazanımları açısından bir farkın olmadığı ancak sınavda sorulan soruların kazanımları ve ünite bazında soru sayıları açısından farklılıklar olduğu belirlenmiştir.
Efektivitas Mediasi terhadap Penyelesaian Perkara Perceraian di Pengadilan Agama
Authors: Muzamzil Ach. , Hermawan Rudi
Published: January 2024

This research aims to find out clearly how effective mediation is in religious courts, whether implementing direct or virtual mediation, in handling divorce cases, and it can be concluded that direct mediation in religious courts is more effective than indirect (virtual) mediation. All civil cases must be resolved through a mediation process first, as well as cases in religious courts, even with technological developments. Perma No. 1 of 2016 which provides the option of mediation, which must be carried out in person, can carry out the mediation process indirectly (virtually) for parties who are unable to attend in person. The method used is a descriptive research method of analysis of mediation theory and its implementation in religious courts. This study found a number of findings that can provide significance for the development of knowledge in the field of religious court procedural law.
Kecanduan Game Online Terhadap Konsumsi Pembelian Virtual Goods
Authors: Maylintang Andien , Utamidewi Wahyu , Kusumaningrum Rastri
Published: January 2024

Game online Genshin Impact yang baru rilis pada tahun 2021 telah berhasil mengantongi 46 miliar rupiah pada tahun rilis pertamanya. Genshin Impact adalah game yang berbasis undian atau gacha dimana pemainnya dapat membeli virtual goods atau item dalam game untuk memenuhi kebutuhan bermain. Kecanduan game online dapat memicu pemainnya untuk berperilaku konsumtif demi mendapatkan apa yang mereka mau. Misi dari penelitian ini adalah untuk mengungkapkan seberapa besar pengaruh kecanduan game online terhadap perilaku konsumtif, dengan menggunakan pengikut akun Twitter @babufess sebagai contoh para pemain Genshin Impact. Penelitian ini mengadopsi metode survei kuantitatif eksplanatori, dengan menerapkan analisis regresi linear sederhana. Teori yang diadopsi dalam penelitian ini adalah Teori Ketergantungan Media. Partisipan dalam penelitian ini berjumlah 100 orang, dan data dikumpulkan melalui kuisioner yang disebar menggunakan skala Likert serta menguji hipotesis koefisien determinasi (R2). Hasil penelitian menunjukkan bahwa terdapat pengaruh signifikan dari kecanduan permainan online Genshin Impact terhadap perilaku konsumtif.
Analisis Sistem Informasi Merekrut Karyawan Berbasis WEB pada Perusahaan PT.Erafone Artha Retailindo
Authors: Damila Miesie Sasikirana , Rezeki Rezeki , Afrida Ayuni , Putra Rachel Pramana
Published: January 2024

Efficient and organized employee recruitment management is very important for the success of a company. In this digital era, web-based technology offers a great opportunity to improve the recruitment process by reducing time, costs and increasing the quality of prospective employees. This study aims to analyze and design an innovative and easy-to-use web-based recruitment system for the company PT ERAFONE ARTHA RETAILINDO to increase efficiency and accuracy in the recruitment process. The research method we use is waterfall and interviews with HR managers and the company's recruitment team to understand the process. current recruitment. We also carry out document analysis, such as historical data on previous recruitment and the recruitment platform used. The results of the system implementation show a significant increase in the response time of the recruitment process and the quality of candidates invited to further selection stages. The HR team also reported reduced workload and increased productivity due to the efficiency of the new recruitment system

Keywords: Information systems, recruiting employees, system design, HR, waterfall