bluuebunny/crossref_metadata_2025 huggingface dataset:
Examining the use of Cannabinoid-based Medicine among older residential care recipients diagnosed with dementia: A study protocol for a double blind randomised cross-over trial
Authors: Timler Amanda , Bulsara Caroline , Bulsara Max , Vickery Alistair , Smith Jill , Codde Jim
Published: November 2019

Background: Dementia is a neurological condition that affects the cognitive and functional ability of the brain and is the leading cause of disability among those aged 65-years and above. More effective ways to manage dementia symptoms are needed as current treatment options (anti-depressant and antipsychotic) can be ineffective and associated with substantial side-effects, including increased rate of mortality. Cannabinoid-based medicines (CBM) has shown to inhibit some symptoms associated with dementia and the adverse effects are often minimal, yet little research has explored the use of CBM among this population. Aim. To monitor the safety of a purified dose of CBM oil (3:2 THC:CBD) on behaviour symptoms, Quality of life (QOL), and discomfort caused by pain. Methods/Design: We will carry out an 18-week randomised, double-blinded, crossover trial that consists of a 2-week eligibility period, two, 6-week treatment cycles and two, 2-week washout periods (between both cycles, and after the second treatment cycle). We aim to recruit 50 participants with dementia who are living in residential aged-care facilities. The participants will be randomised into two groups, and receive a dose of either CBM oil or placebo for the first treatment cycle and receive the opposite medication for the second. The Neuropsychiatric Inventory Questionnaire, Cohen Mansfield Agitation Inventor, Quality of Life-Alzheimer’s Disease questionnaire, and the Abbey Pain Scale will be collected on seven occasions, and completed by the participants, aged-care staff, and nominated next of kin or family member. The participant’s heart rate and blood pressure will be monitored weekly and their body composition and weight will be monitored fortnightly by a research nurse to assess individual dose response and frailty. In addition, pre- and post-surveys will be administered to aged-care staff and family members to understand their perceptions towards CBM, and to inform proposed focus groups consisting of the aged care staff and next of kin. Discussion: The study design has been informed by medical professionals and key stakeholders including those working in the residential aged-care industry to ensure patient safety, collection of non-invasive measures, and methodological rigor and study feasibility. Trial registration: ACTRN12619000474156 Registered 21 March 2019, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=375128&isClinicalTrial=False
Vietnamese EFL Students’ Habits of Using Dictionaries in Translation Practice in ESP Courses
Authors: Tong Lien Thi My
Published: November 2019

Doing translation tasks, especially in English-for-Specific-Purposes (ESP) courses, is probably demanding and challenging, which requires students’ utilization of dictionaries and other tools. Thus, this study was conducted to investigate Vietnamese English-as-a-Foreign-Language (EFL) students’ habits of dictionary consultation in ESP translation. The data were collected during a three-week period among 75 third-year EFL students from three classes at University of Languages and International Studies (ULIS), Vietnam National University (VNU) by a combination of quantitative and qualitative methods (i.e. survey questionnaires with a combination of close-ended and open-ended questions). The research highlighted the students’ positive attitudes towards dictionary use together with a high level of its frequency in translating ESP texts, their definite preference for dictionary applications for mobile phones and bilingual dictionaries as well as their prioritized lookups such as equivalents, examples, equivalent usage, and word definitions. In addition, it revealed that the students were confident in their capability of exploiting the dictionaries in ESP translation and thus had little desire for teachers’ assistance and guidance.
Separation of the Epitopes in a Multi-Epitope Chimera: Helical or Flexible Linkers
Authors: Kabiri Mona , Tafaghodi Mohsen , Saberi Mohammad Reza , Moghadam Maliheh , Rezaee Seyed Abdolrahim , Sankian Mojtaba
Published: November 2019

Background:

The engineered chimeric peptides including functional multi-epitope
structures fused by various peptide linkers are widely applied in biotechnological research to
improve the expression level and biological activity of chimera.

Objective:

The aim of our study was to evaluate the effect of helical and flexible linkers on
solubility, expression level and folding of multi-epitope chimera containing four epitopes of Human
T Lymphotropic Virus Type 1 (HTLV-1).

Methods:

For this purpose, the chimera sequences connected by the helical or flexible linker were
inserted into different plasmid vectors and expressed in E. coli strains. The expressed products were
analyzed using SDS-PAGE and Western blot techniques. Additionally, the molecular modeling
study of the chimera with helical or flexible linker was performed using iterative threading
assembly refinement (I-TASSER) to attain their three-dimensional structures.

Results:

Comparison of the chimera expression indicated that the insertion of a flexible
(GGGGS)3 linker among chimera epitopes could significantly enhance the level of expression,
whereas, the low-level of chimera expression was observed for chimera containing the contiguous
helical (EAAAK)5 linker. According to the results of sequence alignment and plasmid stability test,
the structure and function of a consecutive helical linker among chimera epitopes were similar to
porins as the outer-membrane pore-forming proteins. The molecular modeling results confirmed
our experimental study.

Conclusion:

This investigation illustrated the key role of linker design in determining the
expression level of multi-epitope chimera and conformational folding.
Dietary Fish Oil Concentrates Associated Health Benefits: A Recent Development of Cardiovascular Risk Reduction
Authors: Behera Sudhanshu S.
Published: November 2019

Fish oil is an abundant source of omega-3 (n-3 or ω-3) polyunsaturated fatty acids (PUFAs) and contains
Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA). PUFAs are very effective in preventing/
inhibiting cardiovascular incidents, particularly in individuals with high cardiovascular risk/accidents. In this
review, composition, extraction of fish oil and its favorable/beneficial effects in Cardiovascular Diseases (CVDs)
and molecular mechanism for its treatment/reduction have been discussed. Moreover, the application of fish oil
for preventive/protective and remedial/curative properties in nutritive and health benefits has been summarized.
All these aspects further search the opportunities/hope and scope with its expected opening and anticipations/
possibilities to provide additional therapeutic substitutes for the reduction of CVDs and registration of new
drugs.
Antibiotics Application Strategies to Control Biofilm Formation in Pathogenic Bacteria
Authors: Khan Fazlurrahman , Pham Dung T.N. , Oloketuyi Sandra F. , Kim Young-Mog
Published: November 2019

Background:

The establishment of a biofilm by most pathogenic bacteria has been known as one of the resistance mechanisms against antibiotics. A biofilm is a structural component where the bacterial community adheres to the biotic or abiotic surfaces by the help of Extracellular Polymeric Substances (EPS) produced by bacterial cells. The biofilm matrix possesses the ability to resist several adverse environmental factors, including the effect of antibiotics. Therefore, the resistance of bacterial biofilm-forming cells could be increased up to 1000 times than the planktonic cells, hence requiring a significantly high concentration of antibiotics for treatment.

Methods:

Up to the present, several methodologies employing antibiotics as an anti-biofilm, antivirulence or quorum quenching agent have been developed for biofilm inhibition and eradication of a pre-formed mature biofilm.

Results:

Among the anti-biofilm strategies being tested, the sub-minimal inhibitory concentration of several antibiotics either alone or in combination has been shown to inhibit biofilm formation and down-regulate the production of virulence factors. The combinatorial strategies include (1) combination of multiple antibiotics, (2) combination of antibiotics with non-antibiotic agents and (3) loading of antibiotics onto a carrier.

Conclusion:

The present review paper describes the role of several antibiotics as biofilm inhibitors and also the alternative strategies adopted for applications in eradicating and inhibiting the formation of biofilm by pathogenic bacteria.
Prediction of Epitope-Based Peptide Vaccine Against the Chikungunya Virus by Immuno-informatics Approach
Authors: Anwar Saeed , Mourosi Jarin T. , Khan Md. Fahim , Hosen Mohammad J.
Published: November 2019

Background:

Chikungunya is an arthropod-borne viral disease characterized by abrupt onset
of fever frequently accompanied by joint pain, which has been identified in over 60 countries in Africa,
the Americas, Asia, and Europe.

Methods:

Regardless of the availability of molecular knowledge of this virus, no definite vaccine or
other remedial agents have been developed yet. In the present study, a combination of B-cell and T-cell
epitope predictions, followed by molecular docking simulation approach has been carried out to design
a potential epitope-based peptide vaccine, which can trigger a critical immune response against the viral
infections.

Results:

A total of 52 sequences of E1 glycoprotein from the previously reported isolates of
Chikungunya outbreaks were retrieved and examined through in silico methods to identify a potential
B-cell and T-cell epitope. From the two separate epitope prediction servers, five potential B-cell
epitopes were selected, among them “NTQLSEAHVEKS” was found highly conserved across strains
and manifests high antigenicity with surface accessibility, flexibility, and hydrophilicity. Similarly,
two highly conserved, non-allergenic, non-cytotoxic putative T-cell epitopes having maximum population
coverage were screened to bind with the HLA-C 12*03 molecule. Molecular docking simulation
revealed potential T-cell based epitope “KTEFASAYR” as a vaccine candidate for this virus.

Conclusion:

A combination of these B-cell and T-cell epitope-based vaccine can open up a new skyline
with broader therapeutic application against Chikungunya virus with further experimental and
clinical investigation.
Free Fatty Acid Receptors as New Potential Targets in Colorectal Cancer
Authors: Bartoszek Adrian , Fichna Jakub , Tarasiuk Aleksandra , Binienda Agata , Fabisiak Adam , Krajewska Julia B. , Mosińska Paula , Niewinna Karolina , Salaga Maciej
Published: November 2019

Colorectal cancer (CRC) is one of the most common cancers worldwide. In developed
countries, its mortality remains high, yet the prevalence has established owing to effective screening
programs; however due to the westernization of lifestyle, the incidences in many other countries have
increased. Although the treatment of CRC has improved in the last few years, the side effects of these
approaches cannot be neglected. Recently, members of the family of free fatty acid receptors (FFARs)
have become attractive pharmacological targets in many diseases, including asthma; studies also point
to their role in carcinogenesis. Here, we discuss current knowledge and future directions in FFAR research
related to CRC. Contradictory results of FFARs modulation may derive from the pleiotropic
effects of FFAR ligands, receptor distribution and different signal transduction. Hence, we indicate directions
of further studies to fully use the potential of FFARs in CRC.
Ligand-Based Pharmacophore Modeling and Virtual Screening to Discover Novel CYP1A1 Inhibitors
Authors: Tahir Rana Adnan , Hassan Farwa , Kareem Abdul , Iftikhar Umer , Sehgal Sheikh Arslan
Published: November 2019

Background:

Cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) is an imperative enzyme due to its immersion in the biotransformation of a wide range of drugs and other xenobiotics. The involvement of enzymes in drug metabolism indicates an effective drug target for the development of novel therapeutics. The discovery of CYP1A1 specific inhibitors would be of particular relevance for the clinical pharmacology.

Method:

In the current work, in silico approaches were utilized to identify the novel potential compounds through a diverse set of reported inhibitors against CYP1A1. A dataset of reported compounds against CYP1 belongs to 10 different classes (alkaloids, coumarins, flavonoids, natural compounds, synthetic inhibitors, drugs, MBI’s, PAHs, naphthoquinone and stilbenoids) was retrieved and utilized for the comparative molecular docking analyses followed by pharmacophore modeling. The total eleven novel compounds were scrutinized on the basis of the highest binding affinities and least binding energy values.

Result:

ZINC08792486 compound attained the highest gold fitness score of 90.11 against CYP1A1 among all the scrutinized molecules.

Conclusion:

It has been elucidated that the residues Phe-224, Gly-316 and Ala-317 were conserved in all ligand-receptor interactions and critical for the development of effective therapies. The ADMET property analyses also predict better absorption and distribution of the selected hits that may be used in the future for in vitro validations and drug development.
Anticancer Activity of Platinum (II) Complex with 2-Benzoylpyridine by Induction of DNA Damage, S-Phase Arrest, and Apoptosis
Authors: Li Yu-Lan , Gan Xin-Li , Zhu Rong-Ping , Wang Xuehong , Liao Duan-Fang , Jin Junfei , Huang Zhaoquan
Published: November 2019

Objective:

To overcome the disadvantages of cisplatin, numerous platinum (Pt) complexes have been
prepared. However, the anticancer activity and mechanism of Pt(II) complexed with 2-benzoylpyridine [Pt(II)-
Bpy]: [PtCl2(DMSO)L] (DMSO = dimethyl sulfoxide, L = 2-benzoylpyridine) in cancer cells remain unknown.

Methods:

Pt(II)-Bpy was synthesized and characterized by spectrum analysis. Its anticancer activity and underlying
mechanisms were demonstrated at the cellular, molecular, and in vivo levels.

Results:

Pt(II)-Bpy inhibited tumor cell growth, especially HepG2 human liver cancer cells, with a halfmaximal
inhibitory concentration of 9.8±0.5μM, but with low toxicity in HL-7702 normal liver cells. Pt(II)-
Bpy induced DNA damage, which was demonstrated through a marked increase in the expression of cleavedpoly
(ADP ribose) polymerase (PARP) and gamma-H2A histone family member X and a decrease in PARP
expression. The interaction of Pt(II)-Bpy with DNA at the molecular level was most likely through an intercalation
mechanism, which might be evidence of DNA damage. Pt(II)-Bpy initiated cell cycle arrest at the S phase
in HepG2 cells. It also caused severe loss of the mitochondrial membrane potential; a decrease in the expression
of caspase-9 and caspase-3; an increase in reactive oxygen species levels; the release of cytochrome c and apoptotic
protease activation factor; and the activation of caspase-9 and caspase-3 in HepG2 cells, which in turn
resulted in apoptosis. Meanwhile, changes in p53 and related proteins were observed including the upregulation
of p53, the phosphorylation of p53, p21, B-cell lymphoma-2-associated X protein, and NOXA; and the downregulation
of B-cell lymphoma 2. Moreover, Pt(II)-Bpy displayed marked inhibitory effects on tumor growth in
the HepG2 nude mouse model.

Conclusion:

Pt(II)-Bpy is a potential candidate for cancer chemotherapy.
In Silico Target Identification and Molecular Docking Studies of Natural Cytotoxic Compound Borivilianoside H
Authors: Gupta S. Dutta , Kohli P.
Published: November 2019

Background:

Borivilianoside H is a naturally occurring anti-cancer compound with known cytotoxicity against human colorectal cancer cell line (HCT-116) and human adenocarcinoma cell line (HT-29). The present study describes the pharmacophore modelling, molecular docking, and molecular dynamics simulation approaches to predict the target proteins of borivilianoside H along with its binding affinity to the selected proteins.

Methods:

A 3-dimensional structure of borivilianoside H was constructed using Avogadro from its 2-D coordinates retrieved from the Pubchem Compound database. Target proteins associated with cancers were identified based on the 95% normalized fit score of PharmMapper. The crystal structures of the targets were retrieved from Protein Data Bank and molecular docking was performed with Autodock Vina 1.1.2. MD simulations were carried out via Google Cloud Platform. ADMET characteristics for borivilianoside H were determined using admetSAR web server.

Results:

Among the selected 7 top-ranked target proteins, fibroblast activation protein (FAP) exhibited the highest binding affinity followed by serum albumin (ALB), bone morphogenetic protein 2 (BMP2) and kinesin-like protein 11 (KIF11). However, the best fit was found with KIF11, where both the steroidal and oligosaccharide moieties of borivilianoside H were involved in interacting with the protein cavity. KIF11 was thus found to be the most suitable target for the anti-cancer effect of borivilianoside. ADMET analysis revealed its suitability as an intravenous drug.

Conclusions:

The targets predicted using this approach will serve as leads for the possible use of borivilianoside H, one of the active ingredients of Chlorophytum borivilianum as an anti-cancer drug.
INTERSECTING OPPRESSION OF GENDER AND RACE IN TONI MORRISON’S THE BLUEST EYE AND GOD HELP THE CHILD
Authors: Nurhayati Ari
Published: November 2019

White domination in America can make white ideology of beauty spread and influence the African-American society. Toni Morrison’s novels, The Bluest Eye and God Help the Child, depict the influence. This study attemps to uncover the intersecting oppression of race and gender in the novels and to explain how African-American women cope with the oppression. This study is descriptive qualitative research. The data sources are Morrison’s novels The Bluest Eyeand God Help the Child. The study has two findings. Firstly, African-American society experiences oppression as an impact of the white beauty hegemony. The most disadvantageous oppression is the internalization of white beauty values. Holding such values makes African-American women feel inferior and hate their own physical characteristics that are far from the white ideal of beauty. Meanwhile, African-American women who have darker skin colors experience the hardest oppression because they also become the victims of oppression committed by some circles of African-American society, which tend to consider them unequal. It reflects the complexity of oppression experienced by African-American women. Secondly,self-consciousness is the main factor of attempts to release them from the oppression. Without self-consciousness, African-American women can be trapped in values that deteriorate their self-pride of identity.Keywords: intersecting oppression, African-American women, skin color
Health Researchers’ Use of Social Media: Scoping Review
Authors: Dol Justine , Tutelman Perri R , Chambers Christine T , Barwick Melanie , Drake Emily K , Parker Jennifer A , Parker Robin , Benchimol Eric I , George Ronald B , Witteman Holly O
Published: November 2019

Background

Health researchers are increasingly using social media in a professional capacity, and the applications of social media for health researchers are vast. However, there is currently no published evidence synthesis of the ways in which health researchers use social media professionally, and uncertainty remains as to how best to harness its potential.

Objective

This scoping review aimed to explore how social media is used by health researchers professionally, as reported in the literature.

Methods

The scoping review methodology guided by Arksey and O’Malley and Levac et al was used. Comprehensive searches based on the concepts of health research and social media were conducted in MEDLINE, EMBASE, CINAHL, PsycINFO, ERIC, and Web of Science databases, with no limitations applied. Articles were screened at the title and abstract level and at full text by two reviewers. One reviewer extracted data that were analyzed descriptively to map the available evidence.

Results

A total of 8359 articles were screened at the title and abstract level, of which 719 were also assessed at full text for eligibility. The 414 articles identified for inclusion were published in 278 different journals. Studies originated from 31 different countries, with the most prevalent being the United States (52.7% [218/414]). The health discipline of the first authors varied, with medicine (33.3% [138/414]) being the most common. A third of the articles covered health generally, with 61 health-specific topics. Papers used a range of social media platforms (mean 1.33 [SD 0.7]). A quarter of the articles screened reported on social media use for participant recruitment (25.1% [104/414]), followed by practical ways to use social media (15.5% [64/414]), and use of social media for content analysis research (13.3% [55/414]). Articles were categorized as celebratory (ie, opportunities for engagement, 72.2% [299/414]), contingent (ie, opportunities and possible limitations, 22.7% [94/414]) and concerned (ie, potentially harmful, 5.1% [21/414]).

Conclusions

Health researchers are increasingly publishing on their use of social media for a range of professional purposes. Although most of the sentiment around the use of social media in health research was celebratory, the uses of social media varied widely. Future research is needed to support health researchers to optimize their social media use.
A Mobile Health App to Improve HIV Medication Adherence: Protocol for a Pilot Randomized Controlled Trial
Authors: Ramsey Susan , Ames Evan , Uber Julia , Habib Samia , Clark Seth
Published: November 2019

Background

Adherence to antiretroviral therapy (ART) is essential for allowing persons living with HIV to live longer, healthier lives. However, a large portion of this population has suboptimal adherence and are not virally suppressed. Conventional interventions aimed at improving ART adherence lack portability and scalability, and improvements in adherence are not often sustained. Mobile health (mHealth) ART interventions offer a low-cost and accessible method of improving adherence, but many have limited functionality and do not offer comprehensive support. The combination of an mHealth intervention with a face-to-face adherence intervention and interactive health coaching feature may offer sufficient support in a manner that is sensitive to resource limitations that are often found in HIV treatment settings. This paper details the protocol of a study designed to evaluate the potential of an enhanced mHealth intervention for improving ART adherence.

Objective

The primary objective of this study is to assess the feasibility and acceptability of the Fitbit Plus app enhanced with a face-to-face LifeSteps session (Fitbit Plus condition) for improving ART adherence. In addition, we will determine the preliminary efficacy of the intervention by calculating treatment effect sizes.

Methods

This study will be conducted in 2 phases. The intervention will be developed and piloted with a small group of participants during phase 1. Pilot participants will provide feedback that will be used to refine the intervention for phase 2. In phase 2, a preliminary randomized controlled trial (RCT) comparing Fitbit Plus with a condition that approximates the standard of care (SOC) will be conducted with 60 persons living with HIV. Interviews will be conducted with RCT participants at baseline, and follow-up interviews will be conducted at 1, 3, 6, and 12 months. ART adherence is the primary outcome and will be monitored throughout the study via electronic pill boxes. Effect sizes will be generated using a fractional logit model estimated by generalized estimating equations.

Results

Phase 1 of this trial is complete; data collection for phase 2 is ongoing. Follow-ups with enrolled participants will conclude in January 2020.

Conclusions

This study will contribute to the literature on ART adherence and may produce an efficacious intervention. Owing to a small sample size, there may be insufficient power to detect statistically significant differences between Fitbit Plus and SOC. However, if Fitbit Plus is found to be acceptable and feasible and yields promising effect size estimates, this pilot study could serve as the foundation for a larger, fully powered trial of Fitbit Plus.

Trial Registration

ClinicalTrials.gov NCT02676128; https://clinicaltrials.gov/ct2/show/NCT02676128

International Registered Report Identifier (IRRID)

DERR1-10.2196/15356
Analisis penerimaan pemustaka terhadap electronic theses & dissertations di Perpustakaan Universitas Gadjah Mada
Authors: Kriswanto Y Rudi
Published: November 2019

Introduction. Electronic theses & dissertations is one important service at Universitas Gadjah Mada (UGM) Library  is to simplify the end-user reading service. However,it is still not understood whether the users are satisfied with the new service.  An analysis is needed to examine the user acceptance of electronic theses & dissertations implemented by UGM Library.Data Collection Method. This paper  used an acceptance analysis with a qualitative approach by interviewing three UGM students.Analysis Data. The paper applied  Stuart Hall's theory of encoding-decoding.Results and Discussions. The results showed that the informants were categorises into two  positions. One informant was in a dominant hegemonic position and the others were in  negotiated positions. The background of the study program, the level of education and experiences, might influence the differences in the acceptance and interpretation of electronic theses & dissertations.Conclusions. There are various perspectives of how users examine to the  electronic theses & dissertations at UGM Library.
Peran Perpustakaan Umum Kota Depok pada era teknologi digital
Authors: Rachman Margareta Aulia , Rachman Yeni Budi
Published: November 2019

Introduction. The purpose of this study is to identify the roles of digital technology in the Depok City Public Library. The main challenge of the digital community is the increasing digital divide and the weakening of the identity of local communities which can result in low social participation and involvement in community issues. This study focuses on the characteristics of the people of Depok City to assess the role of public libraries that have the potential to be public spaces and places for social and physical meetings in the digital era.Data Collection Methods. This was a qualitative research with  interviews involving librarians, library directors and  users.Data Analysis. The data was analyzed by involving the process of data reduction, interpretation, and conclusion. The research setting at the chosen was the Depok City Public Library, close to the Capital of Indonesia.Results and Discussion. The results showed that Depok City public library of has several roles in the field of education, information, culture and recreation. These roles can be increased by involving  technology  as a means of library promotion.Conclusion and recommendations. The space and infrastructure in the library can be used optimally for various activities in order to enhance the role of the library as a public space and places for social and physical meetings in the digital era.
Mempertahankan keaslian arsip elektronik di era digital berdasarkan tinjauan literatur sistematis
Authors: Marbawi Muhamad Idris , Salim Tamara Adriani
Published: November 2019

Introduction. This research aimed to understand efforts should be taken so that the authenticity of electronic records can be maintained in the digital environment. Data Collection Method. This research used a systematic literature review published by scientific journals from January 2010 to April 2019 derived from electronic information sources subscribed by the University of Indonesia Library. The results of this review are reported using guidelines for Systematic Literature Review (SLR) which has three stages, namely planning, implementation, and reporting.Analysis Data. Descriptive quantitative was employed to analyze the data by using simple statistic application (Microsoft Office Excel 2007). Results and Discussion. The results indicated that there are 18 literatures (3%) of the total search results of 561 relevant literatures discussing electronic records and ways to maintain their authenticity in digital era. There were 12 articles providing sufficient information about this matter.Conclusion. The majority of the articles mentioned that to maintain the authenticity of electronic archives in digital era must be supported by policy makers such as the government. In addition, the knowledge and skills of archival managers, as well as appropriate technology are also needed.
Para no salir(se) de cauce: la regulación emocional en el trabajo docente
Authors: Martínez Cuevas Guillermo
Published: November 2019

La labor docente expone al profesorado a situaciones que pueden generar un amplio abanico de emociones, las cuales influyen en el desempeño y bienestar de maestros y estudiantes. El objetivo de este trabajo es presentar estrategias que ayuden a regular dichas emociones, a partir de la propuesta de Gross y Thompson. Se plantea la importancia de generar programas de formación de los profesores sobre el tema y de acudir a tratamiento especializado cuando las emociones permanecen a pesar de los intentos de regulación.
¿Cómo y por qué nos formamos los docentes en el uso de tecnología?
Authors: Kriscautzky Laxague Marina
Published: November 2019

En este artículo comparto una reflexión sobre la formación docente en el uso de tecnología, por qué es necesaria, la diferencia entre tic y tac y cómo afrontar el diseño de procesos formativos desde una perspectiva constructivista.
Trayectorias personalizadas docentes: fortalecimiento flexible en la práctica docente
Authors: Barrón Tirado María Concepción , Cervantes Pérez Francisco
Published: November 2019

En este artículo se presenta, de manera general, el Programa Estratégico de Apoyo a la Docencia (pead): “Docencia y aprendizaje en la era digital: trayectorias docentes personalizadas”, como una propuesta integral y flexible para el fortalecimiento de la práctica docente bajo los principios de equidad, inclusión y atención a la diversidad. Se parte de considerar a los docentes como constructores de un saber disciplinario-didáctico en función de sus contextos de trabajo y como agentes de cambio continuo, por lo que un programa de esta naturaleza está orientado a fortalecer su desarrollo personal, social y profesional, con una visión ética, crítica y comprometida con la formación del ciudadano del mundo contemporáneo.
La principal aportación de esta propuesta reside en la articulación entre una visión de la formación docente desde la multirreferencialidad, una organización curricular flexible por ejes y por competencias, un aprendizaje a través de desafíos y actividades, así como un proceso de evaluación continuo; todo ello en el marco de una estructuración didáctica con base en cursos autogestivos y apoyada con el uso apropiado de las tecnologías digitales.
El tránsito hacia la profesión docente: una experiencia compartida
Authors: Castro Zavaleta Ilse Carolina , Nieto Juárez Tania Itzel
Published: November 2019

A lo largo de la historia, las universidades han forjado y desarrollado diversos modelos de formación de sus cuadros docentes. En el caso de la Universidad Nacional Autónoma de México (unam), la ayudantía ha sido uno de los modelos que aún continúa vigente y se ha constituido a su vez como la etapa inicial de la carrera académica de varios profesores universitarios. Recuperar este proceso de formación desde la voz de los sujetos involucrados brinda elementos únicos del trabajo docente en la unam. Así, el presente artículo da cuenta de la experiencia de formación de dos profesoras noveles1 del Colegio de Pedagogía, en la Facultad de Filosofía y Letras (ffyl) de la unam, quienes se desempeñaron como ayudantes de profesor. Ésta es abordada a través de dos momentos: el desarrollo del rol como ayudantes de profesor y el transcurso de su primer año como profesoras de asignatura.
Arte y docencia: una composición lúdica
Authors: Galván Aguilar Nancy Araceli
Published: November 2019

Una de las actividades profesionales más gratificantes que he tenido la fortuna de practicar es la docencia universitaria. Ser profesora en la Facultad de Filosofía y Letras (ffyl) de la Universidad Nacional Autónoma de México (unam) significa, al mismo tiempo y en gran medida, reto y vocación, compromiso y apertura. No ha sido un camino sencillo, pero sí ha resultado una experiencia llena de aprendizajes en términos profesionales y, desde luego, personales. El objetivo de este este texto, por lo tanto, es narrar a modo de testimonio algunos de los aspectos más significativos que han permitido definir mi propio proceso como docente y establecer ciertos principios o ejes orientadores de mi práctica en el aula universitaria, destacando al arte como un recurso valioso para el aprendizaje. Si bien todas las artes poseen un gran potencial para los procesos de enseñanza y aprendizaje, en este artículo resaltaré las experiencias que he tenido con las artes visuales, específicamente en las posibilidades educativas de la fotografía.
AN ANALYSIS OF USING ENGLISH IN CLASSROOM INTERACTION (A STUDY AT THE FIRST GRADE OF A PRIMARY SCHOOL)
Authors: Cahyati Sri Supiah
Published: November 2019

This research entitled: “An Analysis of Using English in Classroom Interactions (A Study at the First Grade of a Primary School)”  to investigated the practice of using English in classroom interactions at the school. It is intended: 1) to identify and describe the teachers' and students' perceptions on the use of English in classroom interactions; 2) to identify, describe, and categorize the techniques of teaching English used by the teachers. The study reported here made use of qualitative research design as its method. It revealed that: all teachers and students regarded the practice of using English in classroom interactions as being useful in order to improve students’ English ability; in the practice of teaching English, teachers used various techniques and language exposures to students; the students’ achievement on the basis of the English syllabus shown that most of the targets in the syllabus were achieved and students could interact with teachers in simple English. However, there were some learning objectives that were not completely achieved, such as writing and reading words in English.
THE CORRELATION BETWEEN MOTIVATION BEHAVIOUR AND SPEAKING ABILITY
Authors: Maulana Diki , Wahyuni Widya Sri , Siregar Detya
Published: November 2019

This researchis aboutthe correlation between motivation behaviour and spekaing abilityat English Students Association. Hence, this research is aimed to find out whether or not there is a significant correlation between motivation behaviour and speaking ability at English Students Association. This research used correlation research design and qualitative research. The instrument is motivation test using questionnaire and speaking test by story telling. The population of this research is English Students Association of IKIP Siliwangi and the sample is 30 students. The data o this research is analysed using pearson product  moment correlation coefficient. The degree of correlation between two variables was low with a correlation coefficient of 0.045. the result showed that there was a weak correlation between motivation behaviour and speaking ability at English Students Association.
AN ANALYSIS OF SPEECH ACT IN ADVERTISING OF CHILD MILK ON TELEVISION
Authors: Novianti Fitri , Maliyani Regina Ratna Dewi
Published: November 2019

Making the advertisement is like we do communication with the others. In speech act, there are words include the meaning to convey the message to the viewers. The aim of this research is to describe the type of act of illocutionary and to analyze the most dominant illocutionary function produced in the advertising. This research is a descriptive research. The subject of this research is child milk advertising on television namely Bebelac 3, Nutrilon Royal 3, and Pediasure. The object of this research is a form of act illocutionary functions contained in advertising speech. Data acquisition uses note technique. Based on the analysis, the researchers get conclusion that the types of act illocutionary found in child milk advertising on television are declarative, representative, expressive, and commisive. In a child milk advertising on television, illocutionary function shows dominance representative and commisive. In the representative, this indicates the presence of a statement and affirmation. Moreover, in the commisives, this indicates the speaker give the promise to the viewers. Keywords:  Pragmatic, Speech act, Advertising
THE INFLUENCE OF TANGIBLE REWARDS TO STUDENT’S MOTIVATION IN 4TH GRADE SDN SINARGALIH 1 CIRANJANG STUDENTS
Authors: Cahya Tedi , Kusnadi Anggraeni Novianti , Anggraeni Anita
Published: November 2019

This study focused on the influence of tangible rewards to students’ motivation on the learning process. The objective of this research is to describe how tangible reward can improve students’ motivation. This research used descriptive qualitative as a research design. The data of this research were obtained from interview to the teacher who teaches in 4th-grade students’ of SDN Sinargalih 1 Ciranjang. The interview was conducted twice. The result of the research would be described in the form of words. The result of the interview, the teacher had tried to apply tangible reward to improve students’ motivation. The teacher was quite good when used the tangible reward to improve the students’ motivation. Meanwhile, the result from teacher interview also showed that the students’ had better motivation from the first meeting to the next meeting. They tried to more active in the process of learning, although some of the students’ are still passive and had less of motivation. Then the result of an interview given to the teacher showed a positive effect. Tangible reward made the students participate actively. It is viewed by the students when the teacher gives some tests to get the reward. The students try to answer teacher question and had no fear to make mistakes.
ANALYSIS OF EDGAR ALLAN POE’S THE TELLTALE HEART BASED ON SPEECH ACT THEORY
Authors: Nina Rostina , Mulandari Asri Pratiwi
Published: November 2019

Abstract This research is analyzing short story “The Tell-tale Heart” by Edgar Allan Poe based on speech act. Speech act consists of categories; representatives, directives, expressive, commissive, and declaratives. Researcher focused on representative speech act. This concerns fictional character of this story as a narrator who utters his belief toward situation he faced. A total of 128 utterances is analyzed and divided into categories of boasting, asserting, stating, informing, claiming, complaining, concluding, criticizing, reporting, describing, suggesting, swearing, and denying. Th result of this research has revealed that 39% representative speech act of reporting category is the most frequently used in the short story while the least including criticizing with 1%. This story is the perfect example of picturing representative speech act while not so many genres do so. By observing some points of utterances, reader will commence to understand the structure of speech act. Keywords:Speech Act, Short Story, The Tell Tale Heart.
THE RELATION BETWEEN STUDENTS’ ANXIETY AND READING COMPREHENSION
Authors: Astuti Dewi Wahyuning , Haris Nadia Fairuz
Published: November 2019

This study aims to analyze the relation of Students’ anxiety and reading comprehension  among senior high school students in Klari Karawang, West Java Province, Indonesia. Participants of this study were thirty students of twelve grade at  SMAN 1 Klari Karawang The study was conducted with a quantitative approach and performed in Klari, Karawang. Based on the findings, the result show there is no significant correlation in Students’ anxiety because in the data show the significant is 0,051 more than 0,05 (> 0,05). The result also show there is no significant correlation in Reading comprehension because in the data show the significant is 0,051 more than 0,05 (> 0,05). Based on the data obtained from thirty participants showed that treat anxiety is 10% , state anxiety is 17%  and situation specific anxiety is 73%.  Measurement of reading  anxiety was done by using Foreign Language Reading Anxiety Scale (FLRAS). Moreover, the researcher give a suggestion for teacher to make a preventive activity, for example to avoid students’ anxiety in reading comprehension, the teacher can provide comfort environment in learning activity, it will help to decrease students’ level of anxiety and it is necessary to motivate student to increase their desire to read more English text and understand the context.
TEACHING VOCABULARY USING FLASHCARD
Authors: Supriatin Titin , Rizkilillah Venska Prajna
Published: November 2019

Vocabulary learning and teaching has been considered as one of the most important mechanisms of any educational program since early. Teachers have been using many techniques to help the learners to develop their knowledge of vocabularies in quality and quantity. There are many media in teaching vocabulary, one of them is by using flashcard. Flashcard is one of media which can help the teacher to teaching English easily. Flash cards in teaching vocabulary are very simple visual aids and the teacher can make the students more active during the teaching learning process. The study was conducted to find out the effect of flashcard on the vocabulary of the sixth graders of elementary school. This study employed a pre-experimental research design with one group pretest and posttest. An the research method used in this research is quantitative research with experimental research method. The subject consisted of 29 students of the sixth grader class of SDN Rengasdengklok Selatan 2 in the academic year of 2017/2018. Data collection techniques used in this study is a test. The procedures of collecting data are pretest, treatment and posttest. The data were analyzed using the SPSS 21.0. Based on the analysis, the mean score in pre-test was 66.21 improve to 79.55 in post-test. The result of t-test showed that significant 2-tailed was lower than 0.05 (0.000 < 0.05). It can be said that H0 is rejected, it means that there is effect of flashcard to the vocabulary of the sixth graders in SDN Rengasdengklok Selatan 2
THE ANALYSIS OF FLOUTING OF CONVERSATIONAL MAXIMS ON THE MAIN CHARACTERS IN “ MOANA” MOVIE
Authors: Nurfarwati Dini , Anisa Siti Nur , Yugafiati Rasi
Published: November 2019

This study focuses to analise the flouting of conversational maxims which are found in Moana movie. The study uses mix method. There are four of maxims can be revealed. The first is maxim relevance. The reasons of maxim relevance are:“The Maui’s responses do not appropriate to Moana’s statements” and “Moana’s response does not appropriate to Maui’s statement”. The second is maxim manner.The reason of maxim manner are: “Moana’s statements do not clear”, “Maui’s response does not appropriate to Moana’s statement”, and “Maui’s statement does not clear”. The third is maxim quantity. The reasons of maxim quantity are: "The Maui’s responses do not appropriate to Moana’s statements”, “Moana’s responses do not appropriate to Maui’s statement”, “Maui’s statement is flouting the maxim”, and “Moana’s steatment is flouting the maxim”. The forth is maxim quality. The reason is “Maui’s responses contain lies”. that among 4 types of maxim in conversation between the main character, Moana and Maui in Moana movie, the maxim of relevance was the most identifiable type. 16 conversations cover 38,1%.  The second is the maxim  quantity. 14 conversations cover 33,3%. The third is the maxim manner. 10 conversation or covers 23,8%. The maxim quality gets 2 conversations and covers 4,8%. The conclusions are the conversation related to ask to do something, be success in doing something, give surprise and do not want something bad happened to the friend.Keywords: Conversational Maxims, Flouting Maxims, Movie
ANALYSIS OF STUDENTS’ LEARNING DIFFICULTY IN ENGLISH LESSON AT MTS NURUL FALAH CIMAHI
Authors: Rachmawati Ema , Rachmawati Mia Selvia
Published: November 2019

This article focuses on the analysis to find out the difficulties of students MTs in English Learning. The sample of this study is used for some students from 36 students in VII grade of MTs Nurul Falah Cimahi. This method uses Qualitative approach in the analysis. The result is that students difficulties, in learning English 85% not appropriate. Some expert suggest external factor and internal factor that be affect students learning difficulties to learning difficulties. The author only focus on one factor that is external factor. External factors are : School factors, Family factors, and Environmental factors. The result of the analysis, the external factors that most affect the difficulties tudent learn English in MTs. Nurul Falah is the School and Family factors
“DEBAT RUKUN ISLAM” WAYANG GOLEK BOBODORAN PERFORMENCE
Authors: Ardiansyah Ardiansyah , Sadikin Irma Savitri , Rizkiani Siska
Published: November 2019

Wayang golek is one of world’s cultural heritage since 2003 that approved by UNESCO and counted as a puppet show. It is performed by Dalang. Dalang on the stage utters the conversation of the wayang and acts as several wayang characters at the same time. In delivering utterance dalang uses different types of tone and also some intonation. Not only to have meaning, but dalang also do it in purpose to deliver the context of the utterance. This research aims to investigate what types of tone that are used and to find out which type is mostly used. This research utilized a video of sundanese wayang golek as the source of data. It used descriptive qualitative design and discourse analysis approach. It was found  that there are five types of tone, such as : rise, fall, fall-rise, rise-fall and level. Those types of tone have their own meaning depending on utterance delivery and discourse context
STUDENTS’ PERCEPTION ON THE USE OF CODE-SWITCHING IN ENGLISH CLASSROOM
Authors: Yana Yana , Nugraha Imam Fauzan
Published: November 2019

This research aimed to investigate students’ perception on the use of code-switching in English classroom and to figure out its advantages for them in learning English. Qualitative research method was applied in this research. The participants of this research were 36 students of 10th grade in vocational high school in Cimahi. There were 36 students involved in the questionnaire and only 9 students involved in the interview session. The data from questionnaire were analyzed based on the theory of Cohen (2010) in (Rahmadani, 2016) to investigate the students’ perception and interview session to figure out its advantages for students in learning English. The result showed that (1) students showed their positive perceptions on the use of code-switching in English classroom being proven by 75% - 95% of the entire students and (2) students got several advantages from the use of code-switching in English classroom; enabling them to understand the material easily, helping them increase new vocabularies, helping them learn English faster, helping them understand every sentence in English easily, helping them take the main point of the learning, helping them avoid confusion, and making them comfort and confident in learning English.