bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness of modern immunotherapy in combination treatment of patients with renal cancer and bone metastases
Authors: Kostritskiy S. V. , Shirokorad V. I. , Semenov D. V. , Kalpinskiy A. S. , Kononets P. V.
Published: August 2024

Aim. To evaluate the effectiveness of modern immunotherapy in combination treatment of patients with renal cancer (RC) and bone metastases (BM).

Materials and methods. Retrospective analysis of 19 patients with RC BM who received nivolumab and ipilimumab at standard dose and frequency in the 1st line of treatment and palliative orthopedic surgeries at the Moscow City Oncological Hospital No. 62 between 2015 and 2023.

Results. Median follow-up was 17 months. Median progression-free survival (PFS) was 6 months (interquartile range (IQR) 4–10 months). One-year PFS was 13 %. Median overall survival (OS) was 13.0 months (IQR 10.5–18.0 months). One-year OS was 60 %, 2-years OS was 42 %, 3-year OS was 29 %. Disease control was achieved in 13 (68.4 %) patients: in 1 (5.3 %) – complete response, in 12 (63.1 %) – stable disease. Adverse events (AEs) of any grade were registered in 15 (79.0 %) patients. Grade III treatment-associated AEs were observed in 2 (10.5 %) patients. There was no therapy discontinuation due to AEs.

Analysis of the effect of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDS) prognosis group on PFS showed insignificant trend towards higher median PFS in intermediate prognosis group compared to the unfavorable prognosis group (p = 0.073). IMDC prognosis group significantly affected OS. Median OS in the intermediate prognosis group was 9.5 months higher than in the unfavorable prognosis group: 16.0 and 6.5 months respectively (p = 0.002). Statistically significant prognosis factors affecting OS in patients with RC BM were concomitant lung and lymph node metastases. Median OS in patients with concomitant lung metastases was 9.0 months, without lung metastases – 16.5 months (log-rank, р = 0.004). Median OS in patients with lymph node metastases was 12.0 months, without lymph node metastases – 17.0 months (log-rank, р = 0.02).

Conclusion. In wide clinical practice, cytoreductive surgeries for symptomatic metastatic bone lesions clinically benefit patients with RC BM providing disease control, increased PFS and OS, improved quality of life.
Features of Educational and Professional Motivation of Students — Future Teachers with Different Locus of Control
Authors: Vostokova J.I. , Dvornikova I.N.
Published: August 2024

The article presents the results of a study of the educational and professional motivation of future teachers with different locus of control. The study involved first-year students of the Pedagogical Education direction (n=80) aged 17 to 21 years (M=18.6; SD=0.83). The following methods were used: “Motivation of studying at a university” (T.I. Ilyina), “Test questionnaire of subjective localization of control” (SLK) (S.R. Pantileev, V.V. Stolin). As a result of the study, it was determined that the locus of control is an important factor determining the educational and professional motivation of first-year students: students with an internal locus of control have a higher level of motivation than students with an external locus of control. Statistically significant differences were revealed in the motives of “gaining knowledge” and “mastering a profession” among students with different locus of control. The indicators of the "graduation" motive do not statistically differ between external and international students. The authors propose recommendations for improving the educational and professional motivation of first-year students in accordance with the peculiarities of their locus of control.
Possibilities of Stress Regulation in Students of Pedagogical University
Authors: Chernykh L.A.
Published: August 2024

The article discusses the concepts of stress, stress resistance, coping behavior, coping strategies as interpreted by domestic and foreign authors, the purpose, and main tasks of coping. The analysis of current stress, the level of its regulation, and the coping strategies applied by students of a pedagogical university showed that more than 50% of the respondents have a high level of current stress, with a very high level detected among students in defectological and natural science directions of preparation. The level of stress regulation (high and medium) was diagnosed, which demonstrated both the adequacy for 44% of the subjects (stress level reduced to normal) and the inadequacy in strength and resistance to stress factors for the remaining respondents (stress remains at high and very high levels). Students use both adaptive and maladaptive coping strategies to regulate the level of stress. Meanwhile, the adaptive coping strategies used by students (self-control, social support, problem-solving planning, positive reappraisal of the situation) statistically significantly reduce the level of current stress.
Participatory Design as a Practice of Interaction with the Educational Spatial Environment
Authors: Panyukova J.G. , Alexandrova E.S.
Published: August 2024

The article discusses participatory design as an interdisciplinary practice of interaction with the educational spatial environment. The directions of researchers approach to practice of social design both in context of organizing the space of the urban environment and the educational landscape are highlighted. The content aspects of the phenomenon of participatory design are indicated, attention is focused on the understanding of participatory design as a tool for actualizing subjectivity in interaction with both the educational spatial environment and the educational environment as a socio-ecological system. The resourse role of participatory design as a practice of interaction with a spatial educational environment for the development of activity and independence of subjects is noted. It is emphasized that one of the possible methodological formats for the study of participatory design as a practice of interaction with the educational spatial environment can be the ecopsychological approach and the typology of subject-environment interactions.
“Systematization” Test in Digital Format to Assess the Level of Development of Logical Thinking of Senior Preschoolers
Authors: Klopotova E.E. , Fedorov V.V.
Published: August 2024

The level of development of a child’s logical thinking in the older preschool age allows us to talk about the effectiveness of the educational work carried out and predict the success of further education at school. The article presents the results of the application modification of the “Systematization” test (authors N.B. Wenger, A.I. Bulycheva) for children of the sixth and seventh years of life from a set of diagnostic methods of mental development of preschoolers (L.A. Wenger) to evaluate logical thinking. The tasks of the test were transferred to a digital format, which simplifies its use. In this format, the “Systematization” test underwent a standardization procedure, as a result of which good external and differential validity was determined, the structure and reliability of the test were proved, age norms for mastering the actions of logical thinking of animation by modern older preschoolers were determined. The results of the study suggest that an adapted version of the test can be used by psychologists for scientific and practical purposes, to accompany the educational process that promotes the development of thinking in older preschool children.
Layered Defenses: Securing Windows Servers and VMware Virtual Machines
Authors: Reddy Gudimetla Sandeep
Published: August 2024

In the modern digital landscape, securing enterprise environments is paramount, with Windows Servers and VMware Virtual Machines (VMs) being foundational components in many organizations. This paper explores a comprehensive, layered defense strategy aimed at enhancing the security posture of Windows Servers and VMware VMs. The layered defense approach integrates multiple security measures across various levels of the IT infrastructure, creating a robust barrier against potential threats. Key aspects of this strategy include physical security, network security, host security, application security, data security, access control, and continuous monitoring. By adopting a defense-in-depth approach, organizations can effectively mitigate vulnerabilities and address diverse attack vectors. Specific measures for Windows Servers involve operating system hardening, deploying antivirus and antimalware solutions, configuring firewalls, enforcing strict access controls, and implementing comprehensive auditing and logging practices. For VMware VMs, the strategy encompasses securing the hypervisor, hardening VMs, segmenting networks, managing access centrally, and establishing robust backup and recovery protocols. The integration and coordination of these security measures are essential for comprehensive protection, requiring well-defined security policies, regular staff training, and an effective incident response plan. By implementing this layered defense strategy, organizations can significantly bolster their security framework, ensuring robust protection of their critical IT assets against the evolving landscape of cyber threats. This approach not only enhances the immediate security posture but also provides a scalable and adaptable framework to address future security challenges in the dynamic digital environment.
Searching stochastic method of the submersible electric pump flow part optimal shape
Authors: Gorbatov Daniil A. , Zharkovskii Alexander A. , Adrianov Artemiy V.
Published: August 2024

BACKGROUND: Modern approaches based on numerical optimization methods are used in development of pumps in order to achieve the high level of efficiency. These methods with use of parametrical models of flow sections of pumps help to find either global or local extremum of an objective function and to obtain the optimal geometric shape of the flow section. The study object is a dewatering electric submersible pump with cantilever working wheel arrangement used in shipbuilding industry.
AIM: Improvement of energy indicators of the flow section of the high-speed electric submersible pump at the nominal operation mode by means of calculation with the use of the stochastic algorithm of search of the global extremum of an objective function that is pump hydraulic efficiency.
METHODS: Search of the optimal shape if the flow section was conducted with the use of mathematical modelling of three-dimensional flow of a viscous fluid in the computational region of the studied object. The parametrical model of the flow section includes nine geometric variables (four variables for a working wheel, five variables for an outlet element) and their variation ranges. The chosen algorithm of search of the global extremum of the objective function is the Latin hypercube method which ensure uniform distribution of geometric variables in the search space. According to the compiled matrix of experiments with various combinations of parameters, direct fluid dynamics simulations of flow in the flow section were performed.
RESULTS: Simulation results showed that it was managed to improve the pump hydraulic efficiency by 7% in comparison with the initial flow section. According to the velocity field analysis, energy indicators improvement was achieved mainly by increasing the width of channels between an electric motor and a housing, leading to velocities decreasing and lowering the level of hydraulic losses in the outlet element of the flow section of the pump.
CONCLUSONS: The Latin hypercube method proved its effectiveness in search of the global extremum of the pump hydraulic efficiency. The obtained result can be used in further as the initial point in search of the local extremum with direct methods in the area around the found global extremum of the objective function.
Physical Activity in Underserved Preadolescents
Authors: Xu Jun , Gong Fang , Zhao Wei
Published: August 2024

Drawing insights from the theory of fundamental causes of disease, this study examined the relationships between socioeconomic
status (SES) and selected risk factors in transitional urban China. Specifically, under China’s distinct institutional and sociocultural
environment, we examined how contextualized SES (i.e., party membership, hukou status, housing ownership, and
subjective social status) and conventional SES indicators (i.e., education, income, and occupation) were associated with physical
inactivity and body mass index (BMI). Utilizing the urban subsample of the 2017 Chinese General Social Survey (CGSS), we found that
individuals with higher education, income, Communist Party membership, and urban hukou status had lower risks of
physical inactivity. However, higher SES with Community party membership, urban hukou, and government jobs also
increased the risks of being overweight, which may be explained by potential countervailing mechanisms. These findings revealed
intricate relationships among SES and risk factors in China. Our study helped contextualize the theory of fundamental causes,
furnished new empirical evidence, and served as a useful reference for future health inequality research in non-Western societies.
Does threatened miscarriage have an influence on maternal & fetal outcomes during pregnancy? - Our experience in Kozhikode, North Kerala
Authors: Narayanan Saikrishna , Rajan Ambika Prema , Kalliyil Fathimathul Jusna , Nair Lakshmi Rajappan , Tajunnisa Tajunnisa M , Shenoy T Heera
Published: August 2024

: Bleeding in early pregnancy is a threat to developing embryo and constitute a significant source of anxiety to both parents, obstetrician. Adverse outcomes included miscarriage, placenta previa, abruption, preeclampsia, caesarean section, preterm labor, and preterm premature rupture of membranes, fetal growth restriction, and low birth weight.

: The aim of this study was to find the association between threatened miscarriage and adverse pregnancy outcomes in both mother and fetus. Objective was to compare the pregnancy outcomes in normal patients (controls) and in those with threatened miscarriage (cases).

: A 1year prospective study was conducted in Kozhikode; Kerala. The study included 140 antenatal patients who were grouped into 70 cases and 70 controls.

: P-value is less than the significance level 0.05. It was found that caesarean section was significantly higher in case (66.2%) than control (42.9%). Pre-term delivery was also found to be higher in case (60.3%) compared to control (15.7%). PPROM was significantly higher in case (11.4%) compared to control (2.9%). Low birth weight was also higher in case (16.2%) than control (1.4%).

: There was significant association between threatened miscarriage and outcomes like Preterm Labor, preterm premature rupture of membranes, caesarean section, fetal growth restriction, and low birth weight. There was no significant association between threatened miscarriage and outcomes like miscarriage, placenta previa, placental abruption, preeclampsia.
A cross sectional study to estimate the health care needs of perimenopausal and postmenopausal women
Authors: Kaur Sukhpal , Rawat Bhim Singh , Saini Sushma Kumari , Sikka Pooja , Saha Pradeep Kumar , Rawat Sarita
Published: August 2024

Perimenopause is the period when a woman moves from the reproductive phase to non-reproductive. Postmenopause is a complete cessation of menstrual cycles for 12 months or more. Menopausal symptoms may affect their health and quality of life.

To estimate the health care needs of perimenopausal and postmenopausal women.

It is a cross-sectional study of one hundred women. Participants of the age group 40-70 years were recruited by using consecutive sampling technique. Data was collected by interviewing participants as per a pretested, and validated questionnaire. Apart from the information profile, data was collected regarding the reproductive profile; Obstetrics history; prevalence of perimenopausal and postmenopausal symptoms; and sources used to acquire information about menopause.

The mean age of participants was 53.04 ± 7.35 years. Mean age of attaining menopause was 46.88 ± 4.93 years. Majority of the participants (96%) were vegetarian, half (50%) were overweight as per their BMI. More than half (56%) of the participants reported never doing exercises. The commonly prevalent menopausal symptoms were hot flushes (88%), more tired than usual (86%), joint pains (82%), depressed mood (78%), facing difficulty falling asleep (65%). Most of the participants (74%) rated their level of knowledge little regarding menopausal symptoms and their management. The most frequently used source of information were television/ internet (52%), and friends (47%).

Participants require education, appropriate health-related information, counselling services, and availability of affordable, reliable, and accurate health care services for the management of menopausal symptoms.
Serum human pregnancy specific glycoprotein 1 in pregnant women with preeclampsia in comparison with normal pregnancy
Authors: Hussein Shatha Sami , Murad Ali Mohamed , Ibraheem Ban Hussein , Ali Sarah Ismael , Saad Liqa Ameer
Published: August 2024

To compare the serum pregnancy specific glycoprotein 1 values of women with preeclampsia with the values of healthy pregnant women.

A total of 90 pregnant women, whom were recruited during their antenatal care visits to the obstetrical department in Hospital, were included. They were divided into two groups: 45 women with diagnosis of preeclampsia and 45 controls who were the women with healthy pregnancy. Blood samples were collected from both groups and the measurement of pregnancy specific glycoprotein 1 was done using an enzyme immunometric assay.

The groups of preeclampsia pregnant women had markedly lower pregnancy specific glycoprotein 1 than the women with the uneventful pregnancies (9.8±3.8 vs 14.3±6.0 ng/ml; p value <0.001). Pregnancy specific glycoprotein 1 can significantly predict preeclampsia (P value <0.001) with an odds ratio of 0.839 and 95% confidence interval of 0.763 – 0.924. By application of receiver operating characteristic curve analysis, it was observed that the cut-off value of pregnancy specific glycoprotien1 for predicting preeclampsia was 10.4 ng/ml with 77% sensitivity and 60% specificity, the area under the curve 0.728 with 95% confidence interval between 0.622 and 0.835, P value < 0.001.

Pregnancies complicated by preeclampsia are associated with decreased maternal serum level of pregnancy specific glycoprotien. This abnormally decreased levels of might be a reflection of stressed or dysfunctional syncytiotrophoblasts, which is related to the pathogenesis of this placental disorder.
Doppler abnormalities and perinatal outcome in growth restricted fetuses in a tertiary care center: A retrospective study
Authors: Vinodhini K  , Coumary A Sendhil
Published: August 2024

Intrauterine Growth Restriction (IUGR), is a significant contributor to foetal and neonatal morbidity and mortality. The majority of prenatal problems that result in negative outcomes can be avoided with early identification and prompt management measures. Doppler ultrasonography is widely used to make the diagnosis of IUGR in foetuses and to monitor the progression in-utero. The purpose of the current study is to predict the perinatal prognosis of foetuses with growth restriction based on doppler abnormalities.

A retrospective analysis was conducted among 134 cases of diagnosed IUGR in routine ultrasound from the year 2015 to 2021. Socio-demographic data, baby delivery details, and the ultrasound details regarding doppler evaluation of Umbilical Artery (UA) and Middle cerebral artery (MCA) were collected. The fetal cerebro-placental ratio (CPR) was then analysed with the fetal outcomes in the cases.

Abnormal doppler was found in 31 out of 134 cases, with a CPR<1. There was significant association of gestational age, mode of delivery and birth weight variables with abnormal doppler. The mean birth weight of the baby (2052 grams), and NICU admission of the babies (17.6%) have also shown statistical association with abnormal doppler (p<0.05).

Doppler velocimetry is the non-invasive method for identifying foetal growth restriction and anticipating perinatal difficulties, which aids the obstetrician in providing good antenatal care and prompt intervention and prevention of perinatal morbidity and mortality.
Histopathological insights into ovarian tumors: A case series perspective
Authors: Savale Apeksha Suresh , Chawla Archi Arun , Jadhav Priyanka Nimbalkar , Sahu Shilpi
Published: August 2024

: Ovarian cancer stands as the third most prevalent cancer among women in India and contributes to 6% of cancer-related facilities emphasizing its significant impact on mortality. Usually, it manifests with nonspecific symptoms in correlation with age, leading to a frequent oversight in early diagnosis causing more advanced stages when intervention becomes challenging.

Case records of six patientsshed light on the diverse spectrum of ovarian neoplasms encountered in clinical practice, highlighting the complexity and heterogeneity within this disease entity of different age groups. In our case series, we found that the overall burden of ovarian cancer was heaviest in the age group 20–45, while the increase was the largest in the age group 50 years and above.

Given their asymptomatic nature, late onset of symptoms, and lack of effective screening facilities, ovarian cancers are known as the “silent killer”. Hence, histopathological examination plays a prime role in diagnosis and for primary optimum treatment management. Tumor markers such as AFP, LDH, and beta hCG serve as supplementary tools in the initial diagnostic process, monitoring treatment response, and post-treatment surveillance. Proactive measures targeting diverse risk factors are essential for effective prevention and treatment strategies.

This case series underscores the critical importance of timely diagnosis of ovarian tumors, particularly in young females. Heightened vigilance is warranted given the potential for diverse presentations, therefore precise categorization into specific histological types is crucial for clinicians to devise timely management strategies for affected patients.
Historiografía del problema de género en el Movimiento Armado Socialista Mexicano (MASM) de los años sesenta y setenta del siglo XX
Authors: Ávila Coronel Francisco
Published: August 2024

Este artículo se propone analizar el problema del androcentrismo en la historiografía del MASM y busca problematizar hasta qué punto la historia tradicional ha invisibilizado a las mujeres. Se recuperan las aportaciones historiográficas de la historia de las mujeres y de la historia de género para establecer una base teórica y metodológica que permita explicar por qué ha prevalecido una narrativa de la guerrilla en masculino y cuáles podrían ser las rutas, preguntas, problemas y metodologías para que las mujeres aparezcan como agentes sociales preponderantes y reescribir la historia del MASM.
Analysis and comparison of retinal vascular parameters under different glucose metabolic status based on deep learning
Authors:   Departments of Laboratory Medicine, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China, Jiang Yan , Chen Xiao-Hong ,   Center of Health Management, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China, Yang Lin ,   Center of Health Management, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China, Xu Jing-Jing ,   Visionary Intelligence Ltd., Beijing 100080, China, Wei Qi-Jie ,   Visionary Intelligence Ltd., Beijing 100080, China, Chen Bin-Bin ,   Ophthalmology Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China, Cai Yong-Jiang ,   Center of Health Management, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China, Xi Wen-Qun ,   Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, Guangdong Province, China, Zhang Zhe ,   Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, Guangdong Province, China
Published: August 2024

AIM: To develop a deep learning-based model for automatic retinal vascular segmentation, analyzing and comparing parameters under diverse glucose metabolic status (normal, prediabetes, diabetes) and to assess the potential of artificial intelligence (AI) in image segmentation and retinal vascular parameters for predicting prediabetes and diabetes.
METHODS: Retinal fundus photos from 200 normal individuals, 200 prediabetic patients, and 200 diabetic patients (600 eyes in total) were used. The U-Net network served as the foundational architecture for retinal artery-vein segmentation. An automatic segmentation and evaluation system for retinal vascular parameters was trained, encompassing 26 parameters.
RESULTS: Significant differences were found in retinal vascular parameters across normal, prediabetes, and diabetes groups, including artery diameter (P=0.008), fractal dimension (P=0.000), vein curvature (P=0.003), C-zone artery branching vessel count (P=0.049), C-zone vein branching vessel count (P=0.041), artery branching angle (P=0.005), vein branching angle (P=0.001), artery angle asymmetry degree (P=0.003), vessel length density (P=0.000), and vessel area density (P=0.000), totaling 10 parameters.
CONCLUSION: The deep learning-based model facilitates retinal vascular parameter identification and quantification, revealing significant differences. These parameters exhibit potential as biomarkers for prediabetes and diabetes.
Psychometric validation of the Chinese version of the dry eye-related quality-of-life score questionnaire
Authors:   Xiamen University Affiliated Xiamen Eye Center, Liu Yu-Wen , Li Jia-Ni ,   Xiamen University Affiliated Xiamen Eye Center, Zhang Yu-Ting ,   Xiamen University Affiliated Xiamen Eye Center, Ouyang Wei-Jie ,   Xiamen University Affiliated Xiamen Eye Center, Wang Yu-Qian ,   Xiamen University Affiliated Xiamen Eye Center, Huang Cai-Hong ,   Xiamen University Affiliated Xiamen Eye Center, Liao Yi ,   Xiamen University Affiliated Xiamen Eye Center, Hu Jiaoyue ,   Xiamen University Affiliated Xiamen Eye Center; Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Liu Zuguo ,   Xiamen University Affiliated Xiamen Eye Center; Fujian Provincial Key Laboratory of Ophthalmology and Visual Science; Fujian Engineering and Research Center of Eye Regenerative Medicine
Published: August 2024

AIM: To psychometrically validate the Chinese version of the dry eye-related quality-of-life score questionnaire (DEQS-CHN) among Chinese patients with dry eye.
METHODS: This study involved 231 participants, including 191 with dry eye disease (DED) comprising the dry eye disease group, and 40 healthy participants forming the control group. Participants were required to complete the DEQS-CHN, and Chinese dry eye questionnaire and undergo clinical tests including the fluorescein breakup time (FBUT), corneal fluorescein staining (CFS), and Schirmer I test. To assess the internal consistency and retest reliability, Cronbach’s α and the intraclass correlation coefficient (ICC) were employed. Content validity was assessed by item-level content validity index (ICV) and an average scale-level content validity index (S-CVI/Ave). Construct validity was assessed by confirmatory factor analysis. The concurrent validity was assessed by calculating correlations between DEQS-CHN and Chinese dry eye questionnaire. Discriminative validity was evaluated through non-parametric tests, with receiver operating characteristic (ROC) curve serving as conclusive indicators of the questionnaire’s distinguishing capability.
RESULTS: The Cronbach’s α coefficients for frequency and degree of ocular symptoms, impact on daily life, and summary score were 0.736, 0.704, 0.811, 0.818, 0.861, and 0.860, respectively, and the ICC were 0.611, 0.677, 0.715, 0.769, 0.711, and 0.779, respectively. All I-CVI scores ranged from 0.833 to 1.000, with an S-CVI/Ave of 0.956. Confirmatory factor analysis results exhibited a well-fitting model consistent with the original questionnaire
CONCLUSION: The DEQS-CHN has been demonstrated as a valid and reliable instrument for assessing the impact of dry eye disease on the quality of life among Chinese individuals with DED.
Nasal flap preservation in endoscopic dacryocystorhinostomy for nasolacrimal duct obstruction
Authors:   School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon; Department of Ophtalmology, Eye and Ear Hospital International, Naccache, Lebanon, Romanos Marianne , Hallit Souheil ,   School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon; Applied Science Research Center, Applied Science Private University, Amman 11937, Jordan, Romanos Bassam ,   School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon; Department of Ophtalmology, Eye and Ear Hospital International, Naccache, Lebanon
Published: August 2024

AIM: To compare surgical outcomes between the conventional endoscopic dacryocystorhinostomy (DCR) and a modified endoscopic DCR for the treatment of nasolacrimal duct obstruction (NLDO), and evaluate factors associated with the surgical success rate.
METHODS: Medical records of patients who underwent primary DCR surgery between January 2016 and July 2020 at the Otorhinolaryngology Department of Eye and Ear International Hospital, Lebanon were reviewed.
RESULTS: The study group consisted of 50 consecutive modified endoscopic DCR and the control group consisted of 138 consecutive conventional endoscopic DCR. The success rates at 1y were 98.0% (49 out of 50) for modified DCR, significantly higher compared to 84.8% (117/138) for the conventional DCR; there was no significant difference in the success rate throughout the years in terms of both surgical techniques. The modified surgery vs traditional [adjusted odds ratio (aOR)=14.96] and having an adjunctive septoplasty surgery vs not (aOR=3.99) were significantly associated with higher odds of success.
CONCLUSION: Mucosal flap preservation and apposition shows significant improvement in the surgical success rate. Moreover, there is no statistically significant difference found in terms of complication rate and mean operative time between the conventional and the modified techniques.
Covering corneal stromal lenticule for macular hole in pathological myopia
Authors:   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Tang Zi-Yan , Zhang Xiao-Juan ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Xie Li-Jun ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Zou Qiang-Xing ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, He Chun-Mei ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Zhao Long ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Yang Hua-Qing ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Quan Yu ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Cao Kui ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, Jiang Hui ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China, He Yu-Kun ,   Wanjiang Eye Hospital of Mianyang, Mianyang 621000, Sichuan Province, China
Published: August 2024

AIM: To evaluate the clinical effect of a new surgery technique (covering corneal stromal lenticule, CSL) for macular hole (MH) in pathological myopia.
METHODS: This was a prospective non-randomized series case study. Fourteen eyes of 14 patients whose axial length were more than 29 mm and suffered from MH and macular hole retinal detachment (MHRD) were included in this study. All cases were treated with 25-gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling, covering CSL and C3F8 gas tamponade. These cases were followed for 6mo, and the best-corrected visual acuity (BCVA), healing status of MH, the reattached rate of retinal detachment (RD), and reoperation rate were analyzed.
RESULTS: All cases were successfully performed the surgery and the postoperative follow-up was completed. After surgery, MHs were healed in all 14 eyes (100%, 14/14) after assessed by optical coherence tomography. The reattachment of retina was achieved in all 6 eyes (100%, 6/6) with MHRD. BCVA was improved in 12 eyes (85.71%, 12/14), and had no significant change in 2 eyes (14.29%, 2/14). The overall mean BCVA was improved from 1.80±0.77 to 0.82±0.46 logMAR (F=10.46, P<0.01). No serious complications occurred in all cases.
CONCLUSION: The new surgery technique (covering CSL) has high reattached rate of RD and high healing rate of MH in pathological myopia in the preliminary study. And it can effectively improve the visual function of patients. This new technique offers meaningful new ideas for treating refractory MH in pathological myopia.
Bone destruction of orbital wall in idiopathic orbital inflammatory pseudotumor: does it always imply malignancy?
Authors:   Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Guo Qi-Han , Huang An-Qi ,   Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Yang Ben-Tao ,   Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Liu Rui ,   Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Wang Nan ,   Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Xu Liang-Yuan ,   Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Ma Jian-Min ,   Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Published: August 2024

AIM: To assess the clinical presentations and outcomes of idiopathic orbital inflammatory pseudotumor (IOIP) patients with orbital wall bone destruction (OWBD) and to propose an expanded classification system that includes bone destruction.
METHODS: The study retrospectively reviewed clinical presentations, imaging findings, treatment modalities, and outcomes of six patients diagnosed histopathologically with IOIP and OWBD at the Beijing Tongren Hospital, Capital Medical University between October 2018 and June 2021.
RESULTS: Over two years, 6 (10%) of 60 IOIP patients at our hospital exhibited OWBD, but this may overrepresent severe cases. The cohort consisted of three men and three women, aged 17 to 60y (mean 35.5±16.1y). Presenting symptoms included proptosis, eyelid swelling, decreased visual acuity with pain, and palpable mass. Imaging revealed multiple anatomical structures involved with the medial wall being the most common site of bone destruction. Histopathological examination showed classic type in five patients and sclerosing type in one patient. All patients underwent surgical resection followed by methylprednisolone treatment. Follow-up (mean 30.3±3.1mo) indicated three patients had no recurrence, while others had varying degrees of symptom persistence or recurrence.
CONCLUSION: IOIP with bone destruction is a rare but significant subtype that mimics malignancy, leading to potential diagnostic and therapeutic challenges. Our findings suggest that complete surgical resection combined with adjunctive glucocorticoid therapy can yield favorable outcomes. However, larger-scale studies are needed to further optimize therapeutic approaches.
Systematic bibliometric and visualized analysis of research hotspots and trends on the application of artificial intelligence in glaucoma from 2013 to 2022
Authors:   Eye School of Chengdu University of TCM, Chengdu 610072, Sichuan Province, China, Liu Chun , Zhu Ke-Yu ,   Eye School of Chengdu University of TCM, Chengdu 610072, Sichuan Province, China, Liu Chun-Meng ,   Eye School of Chengdu University of TCM, Chengdu 610072, Sichuan Province, China, Duan Jun-Guo ,   Ineye Hospital of Chengdu University of TCM, Chengdu 610084, Sichuan Province, China; Key Laboratory of Sichuan Province Ophthalmopathy Prevention & Cure and Visual Function Protection with TCM Laboratory, Chengdu 610072, Sichuan Province, China
Published: August 2024

AIM: To conduct a bibliometric analysis of research on artificial intelligence (AI) in the field of glaucoma to gain a comprehensive understanding of the current state of research and identify potential new directions for future studies.
METHODS: Relevant articles on the application of AI in the field of glaucoma from the Web of Science Core Collection were retrieved, covering the period from January 1, 2013, to December 31, 2022. In order to assess the contributions and co-occurrence relationships among different countries/regions, institutions, authors, and journals, CiteSpace and VOSviewer software were employed and the research hotspots and future trends within the field were identified.
RESULTS: A total of 750 English articles published between 2013 and 2022 were collected, and the number of publications exhibited an overall increasing trend. The majority of the articles were from China, followed by the United States and India. National University of Singapore, Chinese Academy of Sciences, and Sun Yat-sen University made significant contributions to the published works. Weinreb RN and Fu HZ ranked first among authors and cited authors. American Journal of Ophthalmology is the most impactful academic journal in the field of AI application in glaucoma. The disciplinary scope of this field includes ophthalmology, computer science, mathematics, molecular biology, genetics, and other related disciplines. The clustering and identification of keyword nodes in the co-occurrence network reveal the evolving landscape of AI application in the field of glaucoma. Initially, the hot topics in this field were primarily “segmentation”, “classification” and “diagnosis”. However, in recent years, the focus has shifted to “deep learning”, “convolutional neural network” and “artificial intelligence”.
CONCLUSION: With the rapid development of AI technology, scholars have shown increasing interest in its application in the field of glaucoma. Moreover, the application of AI in assisting treatment and predicting prognosis in glaucoma may become a future research hotspot. However, the reliability and interpretability of AI data remain pressing issues that require resolution.
Hidden Benefits of Esg Compliance Will Help Developing Imm Firm Structure for Resilience (Part-II)
Authors: Bhattacharya Jayanta
Published: August 2024

No Abstract.
Generalized Differential Transform Method – Application to Integral Equations of Fractional Order
Authors: Mondal Subhabrata , Biswas Asim , Chatterjee Ayan
Published: August 2024

In this paper, we have used gener-alized differential transform method to solve different types of integral equations of fractional order. All the fractional integrals are written in the Riemann-Liouville sense and fractional derivatives are written in the Caputo sense.
An Approach for Exploring Practical Phenomena In Social Network Analysis
Authors: Srivastav Manoj Kumar , Gupta Somsubhra
Published: August 2024

Social networks like Facebook, LinkedIn, Twitter, WhatsApp, etc. have appeared more often these days, and their importance and influence in human life are growing rapidly. A social network is useful for connecting people to communicate and share information with one another in a virtual setting. A member of a social network can establish relationships with individual members or groups of members in that network. Utilizing networks and graph theory to construct social structures is the process known as social network analysis (SNA). The mapping and measurement of relationships and flows between individuals, groups, organizations, and so on is known as social network analysis (SNA). Social networks are represented using the concept of graph theory, where members of a social network are represented as nodes, and relationships between members are represented by edges, representing links, connections, and so on. The nodes represent the members of the social network, and the relationships between them are formed by the concept that there is either a direct or indirect path between them. Generally, members of social networks can establish relationships with each other using a one-to-one or one-to-many concept. The manner in which two or more members of a social network communicate or act toward one another constitutes relationships. The representation of social networks using graph theory helps to understand the trends in research on the relationships between different types of nodes and to predict the behaviour of nodes in social network analysis. The natural process of learning by doing is the subject of a subfield of computer science called machine learning (ML). ML assists in identifying patterns and the structure of node-to-node relationships in social networks. This paper attempts to study relationships among members of social networks using mathematical graph theory and machine learning.
Human Following Robot Based on Motion Sensing Technology
Authors: Buragohain Vanisha , Das Paromita
Published: August 2024

In the current technological age, robots that follow humans are widespread. We can implement the technique of ‘human following’ in robots to follow a person inside a particular area. Human-robot communication is an integral component in this scenario. The human follower robot can assist us in both residential and industrial settings. Robots already exist to perform tasks at ease to assist humans has become a commendable and important development in the world of technology. Using an Arduino board along with an ultrasonic sensor and infrared sensors, the robot will detect motion and follow the person in motion.
Comparative Evaluation of Deep Learning CNN Techniques for Power Quality Disturbance Classification
Authors: Soni Prity , Soni Prity , Mondal Debasmita , Mishra Pankaj
Published: August 2024

For the power system to be stable and reliable, power quality disturbances (PQDs) must be classified. In this work, deep learning was implemented for the purpose of categorizing PQDs. The transfer learning techniques such as ResNet-50, AlexNet, and GoogLeNet were compared and evaluated for the suitability of classifying PQD signals. Accuracy, classification probability, and explainability through GradCAM- an explainable AI technique was evaluated as a grading reference for the comparative analysis. Examination of the three criteria revealed ResNet-50 as the best among all the three architectures for classifying PQD signals since depending on the accuracy.
Factors affecting the application of strategic management accounting in Vietnamese enterprises
Authors: Dao Ngoc Ha
Published: August 2024

This study aims to provide more in-depth information on the factors influencing the application of strategic management accounting in Vietnamese enterprises. The study uses questionnaire surveys to collect primary data to test the hypotheses in the proposed research model about factors affecting the application of strategic management accounting in Vietnamese enterprises. The survey was conducted using a non-probability sampling method with 64 enterprises; 225 valid survey forms were collected using SPSS 25.0. The analysis includes variable descriptive statistics, scale reliability testing, exploratory factor analysis, multivariate regression analysis, and evaluation of regression assumptions. We used a multivariate regression method to analyze the data. The results confirm the acceptance of the hypotheses, demonstrating a significant influence of the model’s factors on the applications of strategic management accounting. Enterprise size, competition levels, business strategy development, decentralization, technology level, and accounting participation positively impact the application of strategic management accounting in enterprises. In particular, the level of competition is the most vital factor motivating Vietnamese businesses to apply strategic management accounting. The results are empirical evidence to help managers better understand the practice of applying management strategic accounting to make reasonable decisions to practice strategic management accounting and have effective performance. Furthermore, this study suggests more profound research directions aimed at promoting the application of strategic management accounting in Vietnamese enterprises.
The paradox of progress: Unraveling the complex impact of e-government and business ease on economic growth in the Arab world
Authors: Maiss Amale El , Taher Hanadi
Published: August 2024

This research examines how the ease of doing business (EDB) and electronic government (EGOV) collectively influence economic growth in Arab countries. By applying a fixed effects model to panel data from 2004 to 2022, the study encompasses multiple Arab nations to ensure comprehensive and reliable outcomes. The analysis reveals that the combined effect of EDB and EGOV (EGOVEDB) negatively impacts economic growth, where a one percentage point increase in EGOVEDB corresponds to a 3.52 percentage point decrease in GDP. Additionally, the human development index (HDI) shows a minor negative correlation with economic growth, while foreign direct investment (FDI) shows a slight positive relationship with GDP, indicating a limited effect. These findings suggest that instead of solely focusing on implementing e-government initiatives, we should place greater emphasis on attracting investments, enhancing e-government processes (including infrastructure and regulatory frameworks), and improving HDI to promote economic growth in the Arab world.
Determinants of loan repayment performance: A study of microfinance institutions in Nepal
Authors: Lamichhane Basu Dev , Bhaumik Amiya , Gnawali Achyut
Published: August 2024

The study’s main goal is to empirically examine the association between loan repayment performance among microfinance institutions (MFIs) in Nepal regarding institutional characteristics (ICs), client characteristics (CCs), and loan characteristics (LCs). Further, the study emphasizes a causal relationship between the variables that directly corresponds with the regression research model for organic validity. For this, the researcher has chosen twenty Nepalese microfinance institutions along with 217 respondents for the study, respectively. The study found that institutional factors, client characteristics, and loan characteristics were positively and significantly associated with the loan repayment performance of Nepalese MFIs. The above-mentioned variables remain pivotal to determining the loan repayment performance of Nepalese MFIs, including institutional policy formation, loan and savings product design, and corporate culture formation for senior-level management. The results of the study will be effective for Banks and Financial Institutions (BFIs), Microfinance Institutions (MFIs), regulatory authorities, Human Resources (HR) analysts, and planners to take corrective actions to improve the repayment performance of MFIs for credit risk management.