bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of Oil Quality Factors and Fatty Acid Compositions of Some Peanut Varieties
Authors: YILMAZ Mustafa , ŞAHİN Cenk Burak , YILDIZ Reşat , İŞLER Necmi
Published: December 2023

The aim of this study was to determine the oil properties and fatty acid compositions of peanut cultivars (Arachis hypogaea L.) grown as the main crop in the Eastern Mediterranean transition zone of Turkey. The field experiment was conducted at the Oil Seed Research Institute experiment area in the main crop seasons of 2018 and 2019. The experiment was designed according to the randomized complete block design (RCBD) with three replications. Oil ratio, saturated fatty acids (palmitic acid, stearic acid), unsaturated fatty acids (oleic acid, linoleic acid), iodine value, and oleic/linoleic acid ratios were investigated in the experiment. Runner (Georgia Green), Spanish (Florispan), and Virginia market types (Sultan, Brantley, BATEM-Cihangir, BATEM-5025, Arioglu-2003, Halisbey, NC-7, Flower-22, Wilson, NC-V-11, Com, Osmaniye-2005, Gazipasa) varieties were used as plant materials. As a result of this study, NC-V-11 (52.23%) cultivar with the highest oil content was determined, followed by Florispan (52.16%), Brantley (52.10%), and Gerogia Green (51.54%). The lowest oil content was obtained from BATEM-Cihangir (44.57%) variety. Brantley variety was found to have the least palmitic acid ratio with 8.04%, while Florispan variety was found the highest with 12.24%. In terms of stearic acid ratios, the lowest value (1.38%) was determined in Com variety, while the highest value (2.91%) was found in Brantley variety. Brantley variety was found to have the highest oleic acid content (71.83%), which is one of the unsaturated fatty acids. Florispan variety had the lowest oleic acid content (43.70%). While Brantley variety had the lowest linoleic acid ratio (9.78%), it was determined that Com variety had the highest linoleic acid ratio (35.77%). The iodine value varied between 78.71-100.71, the lowest value was in Brantley and the highest value was in Com. The oleic acid/linoleic acid ratio was determined to vary between 1.22 and 7.35, the lowest value was in Florispan and the highest value was in Brantley. As a result of the research, it was determined that the variety with the highest oleic acid ratio in the Eastern Mediterranean Transition Zone was Brantley. Peanuts with high oleic acid content are preferred by producers and consumers because they have good quality and extend the shelf life of products producing with them.
Hububat Üreticilerinin Lisanslı Depoculuğa Bakış Açısı: Yozgat İli Yerköy İlçesi Örneği
Authors: TENGİZ Zehra Meliha , AYYILDIZ Merve
Published: December 2023

Lisanslı depoculuk sistemi, tarımsal ürünlerin sağlıklı koşullarda depolanmasını ve ticaretinin kolaylaştırılmasını amaçlayan bir sistemdir. Üreticiler açısından kaliteli ürünleri daha iyi fiyatlara satış imkanı sağlamasının yanında sanayiler için istedikleri zaman istenilen kalitede ürünü tedarik edebilme imkanı sunan çok yönlü yapıya sahiptir. Türkiye’de giderek yaygınlaşan lisanslı depoculuk sistemi tarım piyasaları için büyük önem arz etmektedir. Bu çalışmanın amacı lisanslı depoculuk sisteminin temelinde bulunan üreticilerin sistem hakkındaki tutum ve davranışlarının belirlenmesidir. Bu amaç doğrultusunda çalışmanın ana materyalini 2021-2022 üretim döneminde, Yozgat ili Yerköy ilçesinde oransal dağılım yöntemiyle belirlenen 76 hububat üreticisinden sağlanan birincil veriler oluşturmaktadır. Elde edilen bulgulara göre hububat üreticilerinin %55.3’ünün lisanslı depoları tercih ettiği, üretilen hububatın %51.4’ünün, ortalama 18.13 ton buğdayın ve 3.15 ton arpanın lisanslı depolarda depolandığı tespit edilmiştir. Üreticilerin lisanslı depoları tercih etmesinde, peşin ödeme alma imkanı, depoların yakınlığı ve yüksek fiyat ile satış olanağı gibi faktörlerin etkili olduğu belirlenmiştir. Diğer yandan bölgede, kendi deposunu (%19.4) kullanan üreticilerde bulunmakta ve bu üreticilerin ticaret amaçlı depolama yapmadığı, yemlik kullanımı için değerlendirdiği belirlenmiştir. Depolama yapılmayan hububat miktarının da yüksek olduğu (%29.2) dikkat çekmektedir. Bu durum son yıllarda yaşanan rekolte kaybı, ürün fiyatlarındaki aşırı yükselme ve artan maliyetlere bağlı nakit ihtiyacını karşılamak amacıyla üreticilerin doğrudan satışa yönelmesi ile ilgilidir. Araştırma sonucunda, üreticilerin lisanslı depolar hakkında yeterli bilgiye sahip oldukları ve lisanslı depolamayı faydalı buldukları gözlenmiştir. Buna karşın üreticilerin lisanslı depolama yapma oranı düşük seviyededir ve lisanslı depoları kullanan üreticilerin %40.5’inin devlet teşviklerinin kaldırılması durumunda depolara ürün bırakmayacağı sonucuna varılmıştır. Buna göre üreticilerin sisteme dahil olması ve lisanslı depoculuk sisteminin işlevsel bir yapı kazanmasında kısa ve orta vadede geliştirilecek ve iyileştirilecek teşvik ve destek politikalarına ihtiyaç duyduğu söylenebilir.
Huş Ağacında Zarar Yapan Nematus (=Croesus) septentrionalis (L., 1758) (Hymenoptera: Tenthredinidae)’in Biyolojisi
Authors: AYKAÇ Ahmet Buğra , ÇALMAŞUR Önder
Published: December 2023

Huş ağacı, Betula pendula Roth. dünyanın birçok bölgesinde yayılışa sahip olan ve 40 kadar türü bulunan önemli bir süs ve orman bitkisidir. Türkiye’de ise Kuzey Anadolu ve Doğu Anadolu bölgelerinde sıkça rastlanmaktadır. Huş ağacında zarar yaptığı bilinen birçok zararlı böcek türü bulunmaktadır. Bu çalışmaya konu olan zararlı türe ait örnekler Erzurum Merkez, Atatürk Üniversitesi Yerleşkesi, Merkez Teke deresi ve Aziziye yerleşkesinden alınmıştır. Çalışmanın amacı, Nematus (=Croesus) septentrionalis'in (L.,1758) huş ağaçlarında biyolojisini ve verdiği zararı belirlemektir. Örnekler 20 Haziran ile 20 Eylül 2019 ve 2020 tarihleri arasında toplanmıştır. Zararlının ekolojisini belirlemek için 2018 yılında bir ön durum değerlendirme çalışması yapılmıştır. Böceğin ergin örneği güneşli günlerde huş ağaçlarından, larvalar ise yedikleri dalların yaprakları ile birlikte budama makası yardımı ile kesilerek toplanmıştır. Pupalar toprağın 4 parmak (10-15 cm) derinliğe kadar çapa yardımıyla kazılmasıyla elde edilmiştir. Toplanan erginler kavanozlara yerleştirilmiş ve etil asetat ile öldürülmüştür. Ölü numuneler küçük bir karton kutuya aktarılarak, kutunun üzerine numunenin alındığı yer, ebadı ve alındığı tarih yazılmış ve laboratuvara getirilmiş, ardından bantlanarak etiketlenmiştir. Larvalar besleneceği yapraklarla birlikte dip kısmında toprak olacak şekilde desikatöre konulmuş, ardından su ile nemlendirilmiş emici pamuk zemine bırakılmış ve larvaları beslemek ve olgunlaştırmak için gün aşırı taze yapraklar laboratuvara getirilmiştir. Araştırma sonucunda Nematus (=Croesus) septentrionalis'in yumurtlama zamanı, larva evresi ve nesil sayısı doğal yaşam koşullarında belirlenmiştir. Bulaşıklık oranını elde etmek için hasarlı ağaç sayısı belirlenirken ayrıca yapraklardaki yumurta ve larva sayısını tespit etmek için rastgele seçilen ağaçların dallarındaki hasarlı yapraklar sayılmıştır. Bu çalışmada Nematus (=Croesus) septentrionalis'in biyolojisi ve huş ağaçlarına verdiği zarar incelenmiştir. Bu konu üzerinde çalışan gelecekteki araştırmacılar için faydalı bilgiler ortaya çıkarılmıştır. Erzurum koşullarında zararlının yılda bir nesil verdiği tespit edilmiştir.
Ozmotik Dehidrasyon ve Mikrodalga Kurutma ile Birlikte Limon Halkalarının Kurutma Koşullarının Optimizasyonu
Authors: YILDIZ Zehra , REYHAN Süleyman
Published: December 2023

Kurutma süresini kısaltmak, ürün kalite özelliklerini iyileştirmek için ozmotik dehidrasyon ön işlemi ile birlikte birçok kurutma tekniği beraber kullanılmış olup, ozmotik kurutma ile mikrodalga kurutmanın birlikte kullanılması da bu yöntemlerden biridir. Ozmotik dehidrasyon ve mikrodalga kurutma işleminin birlikte kullanılarak kurutma yapılması mikrodalga kurutmanın olumsuz etkilerinin azaltılmasına yardımcı olur. Bu çalışmada, limon halkaların ozmotik dehidrasyon ön kurutma işlemi uygulanmasından sonra mikrodalga fırında kurutma koşullarının optimum seviyeleri Yanıt Yüzey Yöntemi ile belirlenmiştir. Yanıt Yüzey Yöntemin de kurutma parametreleri olarak ozmotik dehidrasyon süresi, çözelti derişimi, mikrodalga kurutma süresi ve mikrodalga gücü seçilmiştir. Optimize edilecek yanıtlar ise nem kaybı, çapsal büzülme oranı ve b renk değeri değişimi olarak belirlenmiştir. Dört faktör üç seviye için Box-Behnken tasarımına göre belirlenen 29 deney yapılmış ve yanıtlar alınmıştır. Dört faktörlü üç seviyeli Box-Benchken deneysel tasarım yöntemi, A ozmotik dehidrasyon süresi (60-180 dk), B çözelti derişimi (% 10-20 (w:v)), C mikrodalga kurutucuda kurutma süresi (2-6 dk) ve D mikrodalga güç seviyesi (100-300 W) aralığında uygulanmıştır. Elde edilen veriler ANOVA ile analiz edilmiş ve en yüksek R2 değerlerini veren nem kaybı için 0,9853, çapsal büzülme oranı için 0,9861 ve b renk değeri değişimi için 0,9770 ile kuadratik modellerin uygun olduğu belirlenmiştir. Nem kaybı üzerine C, D, CD, A², C² ve D² değişkenleri, çapsal büzülme oranı üzerine A, C, D, D² değişkenleri ve b renk değeri değişimi üzerine ise A, C, D, A² değişkenlerinin etkisinin önemli olduğu görülmüştür. Kurutma parametrelerinin optimum değişken seviyelerinden olan ozmotik dehidrasyon süresi 120 dk, çözelti derişimi %15, mikrodalga kurutma süresi 4 dk ve mikrodalga güç seviyesi 200 W olarak bulunmuştur.
USABILITY AS A PROBLEM OF EXPRESSIVE WEB DESIGN TOOLS: FROM THE PRACTICE OF WEB USABILITY TO THE CONTEXT OF WEB ACCESSIBILITY
Authors:   Kharkiv State Academy of Design and Arts, KURTSEVA Olena
Published: December 2023

The article is devoted to the problem of analyzing the issue of web usability and web accessibility of using educational web resources in the context of the problems of expressive web design tools. The author considers web usability and web accessibility systems as components of a universal design problem that goes beyond narrow technical issues of website content consumption. An important component of the research discourse of the publication is the study and interpretation of the experience of using educational Internet resources from the point of view of the system of expressive means, aesthetic solutions and artistic and project properties of web design. It is concluded that the artistic nature of an educational website has the capacity for representation within the user experience. It is proved that the parameter of external consistency of expressive means is extremely important for the problem of web accessibility. If a website's learning model uses more than one visual system, this requires coordination of visual solutions at all levels of interface design. The author emphasizes that the practice of gaining experience using an educational web resource is based on functional criteria. At the same time, the usability characteristics are not enough to identifythe typological structure of a certain site and to determine, on this basis, a universal approach to the construction of visual solutions. Practically in all the considered cases there are artistic-figurative or aesthetic-stylistic features, which are either part of the functioning system, or are considered as independent aesthetic components. The inevitability in the functioning of websites requires designers to come up with such solutions that would determine not only the functional properties of the website, but also its artistic direction. The conducted analysis shows that the aesthetics of network Internet resources is formed based on the principles of usability and is a utilitarian system that has its own functionality and a wide range of usage norms. Based on this, educational websites have significant differences compared to representative web resources that form visual messages within a different artistic and figurative system.
MYKHAILO KOZYK – ARTIST AND EXECUTIVE: RETURN FROM OBLIVION
Authors:   Kharkiv State Academy of Design and Arts, GALCHENKO Valeriy , NEMTSOVA Valentina ,   Independent researcher and art critic, SACHKO Volodymyr ,   Independent researcher and local historian, CHUDIYOVYCH Igor ,   Independent researcher and local historian
Published: December 2023

The article is dedicated to the half forgotten Ukrainian artist Mykhailo Kozyk (1879–1947) – a master of impressive still lifes, portraits, landscape paintings, genre paintings and monumental church paintings, as well as an artist of original illustrations. Kozyk belongs to the generation of artists who entered the arena of Ukrainian cultural and artistic life at the beginning of the 20th century. The heyday of his talent came in the 1930s – the first half of the 1940s. During the years of his work, M. Kozyk created more than 500 paintings and monumental paintings, as well as several hundred graphic compositions (most of which are considered lost). For more than 25 years, he was involved in the formation of higher art education in Ukraine. Kozyk taught and was the head of Kyiv Art School (1915), held the position of professor at the Kyiv Institute of Architecture (1918), and Kyiv Art Institute (1925); was a teacher (1932), and then a professor at Kharkiv State Art Institute (1939), acting director of the National Institute of Art during the German occupation of Kharkiv (November 1941 – November 1942), taught painting at the Lviv Academy of Arts (1944). Among his students, the most famous are: Ye. Volobuyev, V. Golovaty, N. Umansky, F. Nyrod, O. Vandalovsky, M. Ashikhman, M. Slipchenko, L. Chernov, V. Yatsenko, G. Tomenko, O. Yakovenko, S. Gruzberg. A purposeful study of the artist’s work began after 1979, when thanks to the insistence of children, friends, and grateful students, the 100th anniversary of the artist’s birth was celebrated. During the time of independence, the period of the early 1910s, and middle 1920s of the master’s work was well studied. However, the period of maturity of the master associated with Kharkiv (1932–1942), as well as the years of his forced stay in Western Ukraine (1943–1946), are not sufficiently reflected in the existing publications. A large part of the present publication is devoted to the last fourteen years of the artist’s life and work. A significant part of the illustrations is published for the first time.
VIKTOR GONTARIV: THE SEARCH FOR NATIONAL STYLE AND NATIONAL FORM
Authors:   Kharkiv State Academy of Design and Arts, NAYDENKO Victoria
Published: December 2023

The article is devoted to the problem of national style and national form in the work of the modern Ukrainian painter Viktor Gontariv. Today, this problem is acutely relevant due to the threat of losing national uniqueness due to the spread of globalization processes in the world, and the high spiritual values preserved in the centuries-old traditions of national culture are often rejected in favor of the market, fashion, the advance of information technologies, mass culture. This leads to the spread of eclecticism, clichés and simply bad taste. For the first time, the painting of V. Gontariv is considered in the context of the direction of creativity of representatives of the Ukrainian line in Ukrainian fine art of the late 20th – early 21st centuries – A. Antonyuk, F. Humanyuk, I. Marchuk, M. Popov, etc. It is emphasized that the basis of the personal variants of the modern Ukrainian national style of these masters is an appeal to the traditions of Ukrainian folk art, the use of images-symbols and images-metaphors. During the analysis of Gontariv’s paintings, special attention was paid to their close connection with traditional Ukrainian mythology and peasant artistic naivety in the works of folk painters of the 1940s – 1950s in the village Sotnytsky Kozachok, in Slobozhanshchyna, where V. Gontariv was born and spent his childhood, and at the same time his national mentality was formed, which ultimately determined the main line of his work. For the first time, common and distinctive features of the variants of the national style of M. Boichuk’s school and V. Gontariv’s school, though these artists worked in different periods of Ukrainian history, were analyzed. Attention is also drawn to the specifics of the direction of the workshops of V. Gontariv at KSADA and M. Storozhenko at the NAFAA. The article reveals that the peculiarities of the national form in the work of V. Gontariv consist not only in the appeal to the principle of convention in the reflecting the shape of objects and building the compositional space, but also in creating a new type of images of the Ukrainian peasantry of the Soviet era.
The Effectiveness of Leadership Styles and Strategies to Improve Nurses‘ Electronic Medical Record Quality Based on Kurt Lewin’s Theory
Authors: Hidayat Imat , Purwarini Justina , Susilo Wilhelmus Hary
Published: December 2023

Aims: This research aims to determine the effectiveness of the leadership style and strategy to improve the quality of nurses' electronic medical records through Kurt Lewin's theoretical
Methods:  This research was quasi-experimental. A total of 91 nurses were participate as a respondents. Data collection was used leadership style questionnaire, Kurt Lewin-based leadership strategies and electronic medical record quality form. The intervention was carried out for 2 weeks and was divided into 3 stages, namely the unfreezing stage, moving stage and refreezing stage. The data analysis used was Wilcoxon test.
Results: The study found that a leadership style change from authoritarian to democratic was observed in the nursing profession. The intervention led to an improvement in the quality of Electronic Medical Records (EMR) from not achieved to achieved. The intervention also led to a significant improvement in EMR quality, with 73 respondents experiencing a change from not achieved to achieved.  
Conclusions: Leadership style changes based on organizational conditions. Leaders must analyze members' characteristics to choose the right style. Kurt Lewin's theory provides leadership strategy training, guiding leaders in making changes step by step. Hospitals should facilitate training to improve nursing room heads' knowledge and quality.
Quantum dark energy in a seven-dimensional universe
Authors: Kesanasetty Sasidhar
Published: December 2023

This paper explains the dark energy and acceleration of the universe by quantizing the space in hidden dimensions, which provides the basis and background for the gravitational force through the curvature of space-time. Space-time is considered to be made of a four-dimensional elastic grid in a seven-dimensional universe in which matter also expands along with the universe. Each cube of the grid is considered a quantum of hidden three-dimensional space of Planck volume containing Planck charge, which makes the universe seven-dimensional. The dark energy is explained by the electrostatic repulsion between the Planck charges in each quantum of the hidden space. Mathematically, this electrostatic repulsion is related to the Hubble constant to explain the accelerated expansion, dark energy, and increase in the cosmological potential energy of matter. Expansion of space-time is considered not due to the creation of the new space but due to the stretching of the existing space-time itself like an elastic ruler where the proper length remains constant. The values of the Planck constant, gravitational constant, permittivity of free space, and Boltzmann constant are shown to vary owing to the expansion of space-time and hence provide falsifiable predictions for this theory. This theory builds a framework for the relativistic Newtonian theory of gravity, the relativistic MONDian (Modified Newtonian dynamics) gravity, identifies a valid reason for the transition of Newtonian gravity to MOND at a0 and eliminates the need for dark matter to explain the dynamics of galaxy clusters.
Interpellating Finance – a dramaturgical model for green bond pricing
Authors: Maresca Alessandro , Dal Maso Giulia , Tripathy Aneil
Published: December 2023

Global financial governance is turning green. Attempting to tackle climate change, financial elites seem to swing confusingly between hesitant and action aimed at relieving the contradictions that led to the crisis, and opportunistic co-optation of critical discourse. Drawing on the work of Althusser, Laclau and Butler, we describe the historical emergence of this green financial apparatus and the related proliferation of green labels and signifiers. Green labels serve as the malleable ground on which a diversity of meanings and positions are articulated and temporarily fixed. Labels are the names through which financiers are interpellated and constituted as green ideological subjects. Through an analysis of the mechanisms of green bonds pricing, and of the actors involved in a green bond boot camp, we contend that the added value of green financial instruments, called the greenium, cannot merely be attributed to the performativity of models and formulas for risk engineering. Rather, it is the material effect of a subjectivation apparatus attuned to the existing relations of production. Ultimately, the greenness which becomes encrypted in the greenium is a process of translation of language of capital valorisation, performed through the tendency of capital to reproduce relations of exploitation in transitional time.
FORMAÇÃO DE PROFESSORES PARA O INGLÊS COMO LÍNGUA FRANCA E O PAPEL DO LIVRO DIDÁTICO
Authors: Kazuyuki Sato Sidney , Saparas Marcelo , Buin Edilaine
Published: December 2023

A homologação da Base Nacional Comum Curricular (BNCC), em 2017, orienta a adoção da abordagem inglês como língua franca (ILF), rompendo assim com o ensino tradicional do inglês como língua estrangeira (ILE). Por esta nova perspectiva de ensino, aponta-se uma dificuldade de docentes de língua inglesa em como adequar suas aulas sob o viés ILF. Sabendo-se que o livro didático é um meio auxiliar para aulas, os objetivos deste artigo foram mostrar, em livros didáticos importados, indícios que apontem para o ensino de ILF e também as marcas de um ensino tradicional do inglês e algumas considerações sobre o olhar para o professor em formação, visando à construção de um ensino que abrace a diversidade e proporcione um ensino de língua inglesa mais inclusivo.
ATENDIMENTOS REMOTOS DE MUSICOTERAPIA PARA UM GRUPO DE IDOSOS DURANTE A PANDEMIA DA COVID-19
Authors: Anastacio Mauro , Rodrigues de Camargo Domingos Ana Carolina
Published: December 2023

No início de 2020 a Organização Mundial da Saúde declarou a pandemia da COVID-19. Neste cenário, o distanciamento social foi uma das principais medidas a serem adotadas. Contudo, a população idosa passou a se queixar mais de solidão, associada ao sentimento de perda e de falta de controle. Uma das ações possíveis foi a adaptação de atividades presenciais para o contexto remoto, incluindo as sessões de Musicoterapia em grupo. Este relato pretende narrar o processo de adaptação dos atendimentos presenciais de musicoterapia a grupos de idosos para o cenário virtual durante a pandemia da COVID-19. Durante o processo foi visível a necessidade de incluir incluídas as demandas relacionadas ao isolamento social. Entre as dificuldades identificadas citamos a falta de acessibilidade a tecnologias e as limitações fisiológicas dos idosos. Entre as oportunidades citamos a manutenção do vínculo, os diferentes aprendizados relacionados às tecnologias e a maior participação de familiares e cuidadores.
AS PERSPECTIVAS DA SAÚDE AUDITIVA NA ATUAÇÃO EM MUSICOTERAPIA
Authors: De Paula Silva Felipe , Simões Pierangela Nota , Roberto Silva Lydio , Vanessa Bohn , Romano França Denise
Published: December 2023

O presente estudo teve como objetivo investigar a autopercepção de musicoterapeutas em relação à saúde auditiva. Uma revisão bibliográfica sobre o tema fundamentou a elaboração do questionário para o levantamento de informações sobre a saúde auditiva desse público. O questionário consistiu em 19 questões que abordaram aspectos relacionados à saúde geral, hábitos auditivos, rotina profissional e de lazer dos 31 participantes. Os dados foram submetidos à análise estatística descritiva e inferencial e as questões abertas foram analisadas separadamente. Os resultados indicaram uma relação entre os dias trabalhados por semana e a presença de zumbido, além de pouca aderência dos profissionais à realização de exames auditivos de rotina, apesar da presença de instrumentos tocados em forte intensidade durante os atendimentos. Foi possível identificar que os musicoterapeutas estão expostos ao risco de perda auditiva, semelhante aos músicos, quando se trata de sons de forte intensidade e tempo de exposição. Entretanto, este tema não vem sendo discutido em eventos científicos e as publicações relacionadas à saúde auditiva de musicoterapeutas são escassas.
INVESTIGANDO A ATENÇÃO COMPARTILHADA DE CRIANÇAS COM TRANSTORNO DO ESPECTRO DO AUTISMO EM SESSÕES DE MUSICOTERAPIA
Authors: Santos Carolina , Miranda da Cruz Fernanda , Perissinoto Jacy , Tamanaha Ana Carina
Published: December 2023

Objetivo: Investigar ocorrências de atenção compartilhada de crianças com Transtorno do Espectro do Autismo (TEA) desencadeadas em sessões de musicoterapia. Método: A amostra foi composta por 31 crianças, de 2 a 8 anos, diagnosticadas com TEA e atendidas por equipe multidisciplinar. Para traçarmos o perfil inicial da criança aplicou-se a versão traduzida da escala Individualized Music Therapy Assessment Profile – IMTAP; para avaliação dos comportamentos não adaptativos utilizou-se o Autism Behavior Checklist – ABC e para avaliação das habilidades de linguagem, a ADL 2. Em seguida, foram filmadas sessões de musicoterapia e analisadas as ocorrências de atenção compartilhada e de pulso compartilhado por meio da ferramenta ELAN. Resultados: No IMTAP, todos os domínios mostraram-se deficitários, sendo os de musicalidade (16,7%), habilidades emocionais (31,5%) e habilidades cognitivas (36,4%) os de menores índices. Foram observadas 20,1 ocorrências de atenção compartilhada (dp=10,8) e 5,0 de pulso compartilhado (dp=1,37).  Conclusão: As estratégias da musicoterapia que mais contribuíram para que as crianças compartilhassem a atenção foram as intervenções realizadas com instrumentos musicais ou com o canto. As ações utilizando o fazer musical (improvisar ou acompanhar canções) foram bastante favoráveis para o engajamento entre o musicoterapeuta e a criança.
INCLUSÃO EM MUSICOTERAPIA
Authors: Nascimento Ansay Noemi
Published: December 2023

O artigo apresenta o texto da Conferência realizada no 17º Congresso Mundial de Musicoterapia, em Vancouver, Canadá, no dia 28 de julho de 2023. O trabalho apresentado, intitulado “Inclusion in Music Therapy: Challenges and News Perspectives”, tratou a respeito da formulação e implementação de políticas nacionais para o reconhecimento do trabalho do musicoterapeuta no Sistema Único de Saúde (SUS) e no Sistema Único de Assistência Social (SUAS) e políticas institucionais que promovem a inclusão de participantes em atendimentos de musicoterapia e de estudantes na Universidade Estadual do Paraná (UNESPAR). Outros aspectos abordados foram a respeito do trabalho dos Centros de Educação em Direitos Humanos da Unespar (CEDH) e seus Núcleos: NERA (Núcleo de Relações Étnico-Raciais), NERG (Núcleo de Relações de Gênero) e NESPI (Núcleo de Educação Especial e Inclusiva), a metodologia do "Grupo aberto em Musicoterapia", implementado pela Profa. Dra. Rosemyriam Cunha e o trabalho realizado no Centro de Atendimentos e Pesquisa em Musicoterapia “Clotilde Leinig”.
Using integrated weed management systems to manage herbicide-resistant weeds in the Canadian Prairies
Authors: Tidemann Breanne Darlene , Harker K. Neil , Shirtliffe Steve , Willenborg Christian , Johnson Eric , Gulden Robert , Lupwayi Newton Z. , Turkington T. Kelly , Stephens Emma C. , Blackshaw Robert E. , Geddes Charles M. , Kubota Hiroshi , Semach Greg , Mulenga Alick , Gampe Cindy , Michielsen Larry , Reid Patty , Sroka Elizabeth , Zuidhof Jennifer
Published: December 2023

Although herbicides have been a dominant and effective weed control strategy for decades in Western Canada, herbicide resistance and the lack of new modes of action have resulted in weed management challenges. Integrated weed management strategies have been shown to be successful in controlling certain weed species that are problematic in cropping systems. The objective of this study was to investigate integrated weed management strategies that have been successful on individual species to determine their applicability to a multiple weed species that may coexist in a field. In addition, harvest weed seed control was incorporated into these integrated weed management strategies to determine its impact in western Canadian cropping systems. A 5-year rotational study was conducted from 2016 to 2020 at Beaverlodge, Lacombe, and Lethbridge, AB; Scott and Saskatoon, SK; and Carman, MB, that incorporated integrated weed management strategies such as rotational crop diversity (including winter annuals and perennials), increased seeding rates, crop silaging, chaff collection, and with or without in-crop herbicides. This research confirmed success in managing some species of weeds such as wild oat when increased seeding rates, 2 years of early cut silage barley, and competitive winter cereals were incorporated into a cropping system, even when no in-crop herbicides were applied. However, some weed growth morphologies (e.g., twining weeds) or life cycles (e.g., facultative winter annuals) were not managed successfully with this combination of strategies. Chaff collection provided incremental weed control benefits but did not serve as a replacement for herbicidal weed control. Weed densities had an apparent impact on the success of these integrated weed management strategies, suggesting that the sooner they are adopted, the more likely they are to be successful at maintaining or reducing weed densities. This study not only showed the ability to reduce reliance on herbicides with strategies that can be effective in Western Canada but also highlighted the need for further understanding of different weed species and their responses to integrated weed management strategies, as well as the complexity of managing a weed community with integrated weed management.
Argipressin-norepinephrine association in the treatment of septic shock: the use of the polydistrectual resistance index as an assessment of vascular compliance
Authors: Barile Alessio , Mazzotta Barbara , Izzi Antonio , Mirabella Lucia , Cinnella Gilda , Paternoster Gianluca , Mincolelli Giuseppe , Recchia Andreaserena , Tonti Maria Pia , Manuali Aldo , Copetti Massimiliano , Restivo Luciano , D’Amora Mauro , Di Fazio Aldo , Innelli Pasquale , Del Gaudio Alfredo
Published: December 2023

Introduction

The hemodynamic management of septic patients involves initial fluid therapy, followed by the use of vasoconstrictors in case of treatment failure. The latest Surviving Sepsis Campaign guidelines suggest the synergistic use of argipressin in addition to norepinephrine when hemodynamic optimization is not achieved with norepinephrine alone.

Methods

In our single-center retrospective observational study, the primary endpoint is the safety of initial norepinephrine-argipressin association treatment, assessed through a reduction in Resistance Index. Our secondary endpoint includes the efficacy of this combination, measured by an increase in Mean Arterial Pressure and a reduction in Resistance Index as an indicator of organ perfusion. The Resistance Index (RI) is evaluated through Power Doppler ultrasound. RI is crucial for assessing multi-district vascular tone and multiorgan perfusion. Patients were categorized into three groups based on their treatment. In Group 1, we analyzed patients treated with norepinephrine alone in incremental doses; in Group 2, we analyzed patients receiving the initial norepinephrine-argipressin association treatment (norepinephrine 0.05 mcg/kg/min-argipressin 0.03 IU/min); in the third group (Group 3), we analyzed patients given argipressin (0.03 IU/min) after norepinephrine (<0.10–0.25≥ mcg/kg/min) to stabilize their hemodynamics (MAP > 65 mmHg). RI measurements were taken in the Renal Artery (ARE), Radial Artery (AR), Central Retinal Artery (CRA), and Superior Mesenteric Artery (AMS) at four different time points: T0 before vasopressor therapy, T1 at 1 h, T2 at 24 h, and T3 at 48 h after vasopressor infusion.

Results

A total of 48 patients were divided into three groups: 17 patients in Group 1, 16 in Group 2, and 15 in Group 3. In Group 1, an increase in Mean Arterial Pressure (MAP) was observed, but there was an increase in RIs in the right CRI and left ARE. In Group 2, there was an improvement in MAP and a reduction in RIs in the right/left CRI, left ARE, AMS, and right AR. In Group 3, there was an increase in MAP and a reduction in RIs in the right/left CRI, left ARE, AMS, and right AR.

Conclusion

Early norepinephrine-argipressin association treatment appears to be a valid strategy for hemodynamic optimization in this patient population.
Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis
Authors: Dagher Suzanne F. , Vaishnav Asmita , Stanley Christopher B. , Meilleur Flora , Edwards Brian F. P. , Bruno-Bárcena José M.
Published: December 2023

Hamamotoa (Sporobolomyces) singularis codes for an industrially important membrane bound ß-hexosyltransferase (BHT), (BglA, UniprotKB: Q564N5) that has applications in the production of natural fibers such as galacto-oligosaccharides (GOS) and natural sugars found in human milk. When heterologously expressed by Komagataella phaffii GS115, BHT is found both membrane bound and soluble secreted into the culture medium. In silico structural predictions and crystal structures support a glycosylated homodimeric enzyme and the presence of an intrinsically disordered region (IDR) with membrane binding potential within its novel N-terminal region (1–110 amino acids). Additional in silico analysis showed that the IDR may not be essential for stable homodimerization. Thus, we performed progressive deletion analyses targeting segments within the suspected disordered region, to determine the N-terminal disorder region’s impact on the ratio of membrane-bound to secreted soluble enzyme and its contribution to enzyme activity. The ratio of the soluble secreted to membrane-bound enzyme shifted from 40% to 53% after the disordered N-terminal region was completely removed, while the specific activity was unaffected. Furthermore, functional analysis of each glycosylation site found within the C-terminal domain revealed reduced total secreted protein activity by 58%–97% in both the presence and absence of the IDR, indicating that glycosylation at all four locations is required by the host for the secretion of active enzyme and independent of the removed disordered N-terminal region. Overall, the data provides evidence that the disordered region only partially influences the secretion and membrane localization of BHT.
Two predicted α-helices within the prion-like domain of TIAR-1 play a crucial role in its association with stress granules in Caenorhabditis elegans
Authors: Fuentes-Jiménez D. A. , Salinas L. S. , Morales-Oliva E. , Ramírez-Ramírez V. A. , Arciniega M. , Navarro R. E.
Published: December 2023

Stress granules (SGs) are sites for mRNA storage, protection, and translation repression. TIA1 and TIAR1 are two RNA-binding proteins that are key players in SGs formation in mammals. TIA1/TIAR have a prion-like domain (PrD) in their C-terminal that promotes liquid-phase separation. Lack of any TIA1/TIAR has severe consequences in mice. However, it is not clear whether the failure to form proper SGs is the cause of any of these problems. We disrupted two predicted α-helices within the prion-like domain of the Caenohabditis elegans TIA1/TIAR homolog, TIAR-1, to test whether its association with SGs is important for the nematode. We found that tiar-1 PrD mutant animals continued to form TIAR-1 condensates under stress in the C. elegans gonad. Nonetheless, TIAR-1 condensates appeared fragile and disassembled quickly after stress. Apparently, the SGs continued to associate regularly as observed with CGH-1, an SG marker. Like tiar-1-knockout nematodes, tiar-1 PrD mutant animals exhibited fertility problems and a shorter lifespan. Notwithstanding this, tiar-1 PrD mutant nematodes were no sensitive to stress. Our data demonstrate that the predicted prion-like domain of TIAR-1 is important for its association with stress granules. Moreover, this domain may also play a significant role in various TIAR-1 functions unrelated to stress, such as fertility, embryogenesis and lifespan.
N-rich chitosan-derived porous carbon materials for efficient CO2 adsorption and gas separation
Authors: Min Han , Zhang Ke , Guo Zhongya , Chi Fengyao , Fu Lili , Li Bin , Qiao Xueyi , Wang Shuang , Cao Shaokui , Wang Bing , Ma Qingxiang
Published: December 2023

Capturing and separating carbon dioxide, particularly using porous carbon adsorption separation technology, has received considerable research attention due to its advantages such as low cost and ease of regeneration. In this study, we successfully developed a one-step carbonization activation method using freeze-thaw pre-mix treatment to prepare high-nitrogen-content microporous nitrogen-doped carbon materials. These materials hold promise for capturing and separating CO2 from complex gas mixtures, such as biogas. The nitrogen content of the prepared carbon adsorbents reaches as high as 13.08 wt%, and they exhibit excellent CO2 adsorption performance under standard conditions (1 bar, 273 K/298 K), achieving 6.97 mmol/g and 3.77 mmol/g, respectively. Furthermore, according to Ideal Adsorption Solution Theory (IAST) analysis, these materials demonstrate material selectivity for CO2/CH4 (10 v:90 v) and CO2/CH4 (50 v:50 v) of 33.3 and 21.8, respectively, at 1 bar and 298 K. This study provides a promising CO2 adsorption and separation adsorbent that can be used in the efficient purification process for carbon dioxide, potentially reducing greenhouse gas emissions in industrial and energy production, thus offering robust support for addressing climate change and achieving more environmentally friendly energy production and carbon capture goals.
Environmental public health communication to engage stakeholders and foster social capacity in poorly involved communities living in industrial contaminated sites: the case study of Porto Torres (Italy)
Authors: Marsili Daniela , Pasetto Roberto , Iavarone Ivano
Published: December 2023

This work aims to discuss the implementation of a communication plan as a key element of the epidemiological study to foster social capacity in the scarcely involved community of the industrial contaminated site of Porto Torres (Sardinia region, Italy). We established an inter-institutional working group committed to developing communication activities and materials ensuring multidisciplinary skills from social and communication sciences to collaborate with the environmental and health experts involved in the epidemiological study. The adopted methodological approach and communication strategy resulted in effective and successful engagement of local institutional and social actors in the design and implementation of targeted communication activities. Designing and implementing environmental public health communication processes with poorly involved communities residing close to industrially contaminated sites is critically important. In these areas, environmental noxious exposures associated with high health risks are frequently combined with low socioeconomic conditions. This calls upon mechanisms of environmental injustice, distributive and procedural, and emphasizes the need to prioritize interventions based on integrative strategies securing local communities' engagement through informed participation. Based on the lessons learned in this community-focused experience in Italy, we have identified key actions for suitable environmental public health communication to foster social capacity and promote procedural environmental justice in communities living in other industrial contaminated sites.
Efficacy of acupuncture for hypertension in the elderly: a systematic review and meta-analysis
Authors: Wang Tianyi , Li Hangyu , Feng Shixing , Wang Junqi , Qin Wanli , Zhang Yuan , Sun Wen , Wang Chenlu , Cai Xuanyi , Han Dongran , Liu Jialin , Liu Yixing
Published: December 2023

Background

Hypertension has now developed into a major public health problem worldwide. Under the existing antihypertensive drug treatment paradigm, problems such as decreasing drug resistance and increasing drug side effects can occur for elderly patients. Acupuncture, a core technique in the non-pharmacological treatment of Chinese medicine, plays an important role in the treatment of elevated blood pressure.

Objective

This study aimed to systematically evaluate the effect of acupuncture alone or in combination with antihypertensive drugs on the efficiency of reducing blood pressure and controlling blood pressure in elderly patients with hypertension.

Methods

Articles of randomized controlled trials of acupuncture for hypertension in the elderly published before November 2022 were searched in 7 databases. The methodological quality of the literature was evaluated using the Cochrane Risk of Bias Assessment Tool. The primary outcome was the efficiency rate of blood pressure reduction, and the secondary outcome was the change in blood pressure after treatment.

Results

This study conducted a systematic review and meta-analysis of 12 randomized controlled trials with a total of 1,466 subjects. Among the primary outcome—efficiency rate, acupuncture-only treatment (RR = 1.11, 95% CI: 1.03–1.20, P < 0.01) and acupuncture combined with antihypertensive drug treatment (RR = 1.18, 95% CI: 1.06–1.31, P < 0.01) were significantly different compared with drugs-only treatment. Among the secondary outcomes, SBP (MD: −4.85, 95% CI: −10.39 to −0.69, P = 0.09) and DBP (MD: −1.45, 95% CI: −5.35 to 2.45, P = 0.47) show no significant difference between acupuncture-only treatment and drug-only treatment. Compared to drugs-only treatment, acupuncture plus drugs has more significant efficiency in lowering SBP (MD: −9.81, 95% CI: −13.56 to −6.06, P < 0.01) and DBP (MD: −7.04, 95% CI: −10.83 to −3.24, P < 0.01).

Conclusion

For elderly patients with hypertension, acupuncture-only treatment has the same efficiency and antihypertensive effect compared to drug therapy and acupuncture plus drugs outperforms drugs-only treatment. If the patients receive therapy with less frequency per week and longer duration, there will be a more obvious antihypertensive effect. Due to the methodological defects in the included study and the limited sample size of this paper, more well-designed randomized controlled trials are needed for verification.

Systematic Review Registration

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022376407, PROSPERO (CRD42022376407).
Long-term QT prolongation in monkeys after doxorubicin administration at doses similar to breast cancer therapy
Authors: Bodziock George M. , Meléndez Giselle C.
Published: December 2023

Background

Studies in small animals and human patients have suggested that anthracyclines may prolong cardiac repolarization, or at least inhibit repolarization reserve, predisposing to QT prolongation and dangerous arrhythmias such as Torsades de pointes. This association in humans is difficult to confirm due to multiple confounding variables such as the presence of other medications and concurrent illness.

Objectives

Identify a long-term association between anthracycline administration and repolarization prolongation in nonhuman primates, which can be measured as prolonged QT/QTc intervals on surface electrocardiogram.

Methods

Five female African Green monkeys (AGMs) aged 13 ± 1 years received Doxorubicin (Dox) at doses similar to women treated for breast cancer (30–60 mg/m2/biweekly IV, total cumulative dose: 240 mg/m2) and underwent 12-lead electrocardiogram (ECG) before and 15 weeks after the final dose of Dox treatment. A blinded paired analysis was performed on ECG derived heart rate (HR), QRS, QT and QT corrected for HR (QTc) interval durations.

Results

After Dox, all monkeys exhibited increased QT (BL: 323.2 ± 27.4 ms vs. Post-Dox: 366.4 ± 18.7 ms, p = 0.002) and QTc (BL: 440.2 ± 22.8 ms vs. Post-Dox: 500.8 ± 22.0 ms, p = 0.009) intervals, without any significant changes in HR or QRS duration (p = 0.92 and p = 0.47 respectively).

Conclusions

AGMs treated with Dox exhibited long-term QT and QTc prolongation, along with the expected cardiotoxicity (LVEF decrease). While similar findings were shown in small animal studies, confounders make human association difficult to prove. Our finding provides a valuable intermediary step, showing direct effect of Dox on repolarization in nonhuman primates.
Effects of empagliflozin on right ventricular adaptation to pressure overload
Authors: Axelsen Julie S. , Nielsen-Kudsk Anders H. , Schwab Janne , Ringgaard Steffen , Nielsen-Kudsk Jens Erik , de Man Frances S. , Andersen Asger , Andersen Stine
Published: December 2023

Background

Right ventricular (RV) failure is the prime cause of death in patients with pulmonary arterial hypertension. Novel treatment strategies that protect the RV are needed. Empagliflozin, a sodium-glucose co-transporter-2 inhibitor, shows cardioprotective effects on the left ventricle in clinical and preclinical studies, but its direct effects on RV remain elusive. We investigated the effects of empagliflozin on RV dysfunction induced by pulmonary trunk banding (PTB).

Methods

Male Wistar rats (116 ± 10 g) were randomized to PTB or sham surgery. One week after surgery, PTB animals received empagliflozin mixed into the chow (300 mg empagliflozin/kg chow; PTB-empa, n = 10) or standard chow (PTB-control, n = 10). Sham rats (Sham, n = 6) received standard chow. After five weeks, RV function was evaluated by echocardiography, cardiac MRI, and invasive pressure-volume measurements.

Results

PTB caused RV failure evident by decreased cardiac output compared with sham. PTB-empa rats had a 49% increase in water intake compared with PTB-control yet no differences in hematocrit or blood glucose. Treatment with empagliflozin decreased RV end-systolic pressures without any changes in RV cardiac output or ventricular-arterial coupling (Ees/Ea). The decrease in RV end-systolic pressure was complemented by a slight reduction in RV cross sectional area as a sign of reduced hypertrophy. Load-independent measures of RV systolic and diastolic function were not affected in PTB-empa rats compared with PTB-control.

Conclusion

Empagliflozin treatment reduced RV end-systolic pressure in RV failure induced by pressure overload. Further studies are needed to elucidate whether this simply relates to a diuretic effect and/or additional independent beneficial RV effects.