bluuebunny/crossref_metadata_2025 huggingface dataset:
THE IMPACT OF E-LEARNING ON ADOLESCENTS' KNOWLEDGE ABOUT PRE-MARRIAGE SEXUAL BEHAVIOR
Authors: Hudhariani Rose Nur , Mujahidah Sa'adah , Sari Nova Astika
Published: November 2024

A Health Office report stated that in 2022, 1.9% of teenagers in the Grobogan Regency became pregnant outside of marriage. These adolescents range in age from 15 to 19. Because neither parents nor teenagers can comprehend it, premarital sexual activity is rarely discussed by either group. Teenagers who engage in sexual activity before marriage have access to a limited number of counselling and advocacy centres. There are a lot of young people who participate in risky sexual behaviour before they get married without being aware of the implications. The study utilized a quantitative quasi-experiment with pre- and post-tests administered to a single group. The investigation was carried out in March and April 2024 in the villages of Karanglangu, Kedungjati District, and Grobogan Regency. There were 72 participants in this study. E-learning was provided to the respondents for a period of six weeks. A paired T-test was the statistical test that was chosen. A P-value of 0.000, which is less than 0.05, was found in the statistical test results. It would appear that this form of education impacts the comprehension of premarital sexual behaviour among adolescents.
Влияние экономической науки на современное развитие России
Authors: Л.П. Клеева
Published: November 2024

В статье исследуются основные особенности экономической науки, выделяющие ее из прочих отраслей науки. Рассматриваются возможности ее влияния на формирование и проведение государственной политики в целях активизации социально-экономического развития России. Анализируется взаимное влияние научных результатов, полученных в этой области, и проводимой в стране экономической политики.

The article examines the main features of economic science that distinguish it from other branches of science. The possibilities of its influence on the formation and implementation of state policy in order to enhance the socio-economic development of Russia are considered. The mutual influence of scientific results obtained in this area and the economic policy pursued in the country is analyzed.
Increasing Urban Flood Challenges: Spatial Analysis of the 2024 Flood in Rajabasa, Bandar Lampung, Indonesia
Authors: Rohman Arif , Septiana Trisya , Despa Dikpride
Published: November 2024

This study explores the spatial analysis of flood-prone areas in Rajabasa by utilizing Digital Elevation Model data from DEMNAS and high-resolution aerial photographs obtained via commercial drones. The research aims to understand the region’s flood dynamics and watershed characteristics. The elongated shape of the Rajabasa basin, with a calculated circularity ratio (Rc) of 0.19, indicates that runoff follows the existing stream network, resulting in gradual and prolonged flood events. Field surveys were conducted to validate land cover data, revealing that the majority of the area was residential and classified under Hydrology Soil Group (HSG) D, leading to high Curve Number (CN) values between 88 and 93. These values suggest that nearly all rainfall converts to runoff, exacerbating flooding conditions. Effective flood management strategies were proposed by focusing on areas with the highest CN values and integrating long-term land improvement with short-term flood control infrastructure. The study also highlights the importance of preserving natural drainage lines, which are often overlooked, for enhancing flood mitigation, educating residents about floodplain management, and implementing proper land use regulations. The findings underscore the necessity of combining spatial analysis, high-resolution data, and targeted flood management strategies to mitigate flood risks in Rajabasa and similar flood-prone areas.
ANALISA KEKUATAN PIPA ELBOW 450 TERHADAP ALIRAN FLUIDA MINYAK BAHAN BAKAR PADA KAPAL TUGBOAT
Authors: Muvariz Mufti Fathonah , Al Quarisbi Kharisma , Fyona Annisa , Abdurrahman Prasetyo Naufal , Gemala Mega , Pamungkas Nurman , Pujo Leksonowati Nur Fitria , Yuniarsih Nidia
Published: November 2024

Pipa pada kapal tugboat sangat berperan penting dalam operasisnya, terutama pada pipa penyalur minyak bahan bakar ke mesin utama kapal. Dalam operasinya minyak bahan bakan disalurkan melalui pipa berbentuk elbow 450, sehingga perlu dilakukan analisa respon struktur pada pipa tersebut. Namun berdasarkan pengetahuan peneliti, masih sangat jarang yang melakukan analisa respon struktur pipa dengan mempertimbangkan proses fabrikasi pipa tersebut. Maka tujuan penelitian ini adalah untuk menentukan respon struktur pipa akibat aliran fluida terhadap variasi diameter dalam dan proses fabrikasi pipa. Proses fabrikasi pipa yang dimaksud adalah proses bending dan proses pengelasan. Metode fluid-structure interaction digunakan pada penelitian ini, dimana analisa dilakukan dengan pendekatan computational fluid dynamic untuk mendapatkan distribusi tekanan pipa dan static structural untuk mendapatkan respon struktur. Dapat disimpulkan bahwa semakin kecil diameter dalam pipa maka semakin besar pula respon struktur yang terjadi pada kecepatan inlet yang sama. Pada bagian pengelasan perlu ada perhatian khusus karena distribusi tegangan yang terjadi hanya kurang 12% dari pada bagian sekitar elbow pipa. Pada peneltian selanjutnya perlu dilakukan analisa respon struktur pipa akibat adanya cacat pada saat fabrikasi dan menghitung sisa umur struktur tersebut.
Tryptophan metabolism: role in modulating the function of the "brain–gut axis"
Authors: Slyusar N.A. , Saltanova S.D.
Published: November 2024

The "brain–gut axis" is a bidirectional network of information exchange between the gut and the brain, in which tryptophan metabolism plays a central role, which is directly and indirectly regulated by the gut microbiota. Modulation of the gut microbiota composition is a promising therapeutic strategy for diseases associated with dysfunction of the "brain-gut axis". The aim of the study was to summarize the available literature data on the role of tryptophan metabolism in modulating the function of the "brain–gut axis". The current national and international scientific literature on the role of tryptophan metabolism in modulating the brain–gut axis was analyzed. To search for literature sources, the databases Scopus, PubMed, ResearchGate, Wiley Online Library, Google Scholar for 2018–2024 were studied, a total of 33 sources. The study described the mechanisms of serotonin and kynurenine synthesis. The impact of the gut microbiota on tryptophan metabolism in the gastrointestinal tract is considered. The role and place of serotonin, kynurenine and microbial tryptophan metabolites in the functioning of the "brain–gut axis" are described. We concluded that the gut microbiota modulates the function of the "brain–gut axis" through the interaction between the immune system, bacterial metabolites, and changes in tryptophan metabolism. Due to the fact that the composition of the gut microbiota of animals and humans is different, it is not possible to extrapolate the results of animal studies on the pathogenesis, pathophysiology and treatment of "brain–gut axis" disorders to the human population. There is a need for further human studies to explore the possibility of using tryptophan and its metabolites as biomarkers for diagnosis and development of new therapeutic strategies for diseases associated with "brain–gut axis" dysfunction. One of the options for such treatment may be methods of intestinal microbiota rebiosis that modulate tryptophan availability.

Keywords: serotonin, kynurenine, central nervous system, gut, gut microbiota.
RePPOL : un projet d’édition numérique d’une enquête sur les croyances et les pratiques religieuses dans le Kent (Angleterre, 1543)
Authors: Spina Olivier
Published: November 2024

Cet article présente un retour d’expériences sur le projet d’histoire numérique Rethinking the Prebendaries Plot On Line (RePPOL) mené entre 2019 et 2023 en collaboration avec Aude de Mézerac-Zanetti (Université de Lille) et des ingénieures de la MESHS de Lille.RePPOL est un projet au croisement de la recherche et de l’enseignement. Son premier objectif était de rendre disponible aux chercheurs travaillant sur le règne d’Henri VIII d’Angleterre, un document unique : le manuscrit 128 conservé dans la Parker Library (Corpus Christi College, Cambridge). Il s’agit d’un dossier d’enquête menée en 1543 par l’archevêque de Cantorbéry sur les pratiques et les croyances religieuses hétérodoxes d’un certain nombre d’habitants du Kent. Mais RePPOL se voulait un projet collaboratif associant aux travaux de transcription et d’édition numérique plusieurs étudiants de master, dans une démarche de formation par la recherche (paléographie anglaise, encodage…).Cet article met en lumière les principaux défis scientifiques et techniques rencontrés au cours de RePPOL : choix des outils technologiques les plus pertinents pour une transcription collaborative, dialogue et arbitrages entre ingénieurs et chercheurs quant à la forme du délivrable, prise en compte des contraintes d’argent et de temps pour la définition même du contenu du projet.L’édition numérique finale est aujourd’hui consultable (https://reppol.meshs.fr/).
Urgensi Pembentukan Aturan dalam BPH Migas sebagai Optimasi Kelalaian Safety Standards Depot Minyak Pertamina
Authors: Nuhi Muhammad Hanan
Published: November 2024

Minyak dan gas bumi adalah produk penting negara dan merupakan kekayaan tambang Indonesia yang memerlukan regulasi yang mengatur safety standards terkait keamanan kegiatan usaha. Namun, regulasi mengenai safety standards di Indonesia belum terdapat kejelasan dan belum mengkhususkan standar keamanan penyimpanan minyak, alias terdapat kekosongan hukum. Sehingga, kekosongan hukum dalam regulasi yang ada mengakibatkan kegiatan usaha PT Pertamina khususnya bagian Depot melalaikan standar keamanan mereka. Melihat permasalahan tersebut, maka penulis merumuskan dua rumusan masalah yakni komparasi aturan safety standards depot minyak Indonesia dengan Arab Saudi serta penambahan substansi dalam BPH Migas sebagai upaya optimasi safety standards depot minyak. Penulis menggunakan metode kualitatif dengan pendekatan perundang-undangan dan pendekatan konseptual. Berdasarkan hasil penelitian menunjukan bahwa peraturan safety standards dalam BPH Migas saat ini tidak mengatur secara detail, khusus, dan rinci mengenai aturan laporan inspeksi teknis, standar keamanan, dan sanksi yang berbanding terbalik dengan peraturan safety standards Saudi Aramco milik Arab Saudi. Dengan demikian, sebagai langkah upaya optimasi masalah kelalaian safety standards depot minyak Pertamina maka diperlukan revisi atas peraturan mengenai keamanan kegiatan usaha, yakni dengan menambah beberapa substansi baru yang diharapkan akan mengurangi kelalaian pertamina sebab aturan terkait safety standards akan secara tegas diatur dan akan menekankan sanksi bagi yang melanggar aturan.
Tinjauan Yuridis Terhadap Reformulasi Garis-Garis Besar Haluan Negara Dalam Agenda Amandemen Ke-V Undang-Undang Dasar 1945
Authors: Rosiana Silvia , Thoriq Ahmad Reihan , Alamsyah Farsya Dalila
Published: November 2024

Pasca Amandemen UUD 1945, lahir rencana yang memuat arah pembangunan jangka panjang bernama RPJP yang dimuat dalam UU No. 25 tahun 2004 tentang Sistem Perencanaan Pembangunan Nasional (SPPN) sebagai pengganti dari dihapuskannya Garis-Garis Besar Haluan Negara (GBHN). Belakangan, muncul wacana penghidupan kembali GBHN melalui agenda amandemen ke-V UUD 1945. Wacana ini menjadi diskursus publik karena banyak pihak yang menganggap bahwa pembangunan saat ini tidak terarah sehingga perlu untuk menghidupkan kembali model perencanaan pembangunan seperti GBHN. Namun, timbul  pertanyaan bahwa apakah penghidupan GBHN diperlukan ketika pembangunan saat ini sudah mempunyai rancangan sistem perencanaan nasional yang sistematis dan apakah nantinya GBHN dapat bekerja sejalan dengan sistem pemerintahan saat ini yaitu pemerintahan presidensial. oleh karena itu penelitian ini membahas tentang urgensi penghidupan kembali GBHN dalam wacana amandemen ke-V UUD 1945 dan Bagaimana implikasi menghidupkan kembali GBHN terhadap kedudukan MPR dengan menggunakan metode penelitian hukum normatif dan mendapatkan kesimpulan bahwa penghidupan kembali GBHN bukan merupakan suatu keperluan yang mendesak karena sudah ada model perencanaan yang sudah sistematis dan menyeluruh yaitu SPPN dan wacana GBHN perlu ditolak karena sudah tidak sejalan dengan struktur pemerintahan presidensial yang telah disepakati untuk dipertahankan dalam perubahan Undang-Undang Dasar 1945 dan dapat menimbulkan berbagai implikasi bagi ketatanegaraan Indonesia.
Implementasi UN Model Law dalam Penolakan Pelaksanaan dan Pembatalan Putusan Arbitrase pada Perma 3/2023
Authors: Gunawan Muhammad Gilang , Gracia Frestiany Simanjuntak
Published: November 2024

Abstrak: Dalam UN Model Law terdapat ketentuan mengenai syarat-syarat agar dapat dilakukannya penolakan pelaksanaan dan pembatalan putusan arbitrase. Ketentuan tersebut diatur dalam Pasal 34 dan Pasal 36 UN Model Law. Sementara itu, Indonesia belum mengadopsi UN Model Law dalam Undang-Undang No. 30 Tahun 1999 Tentang Arbitrase dan Alternatif Penyelesaian Sengketa. Baru-baru ini, Mahkamah Agung mengeluarkan Peraturan Mahkamah Agung Nomor 3 Tahun 2023 tentang Tata Cara Penunjukan Arbiter Oleh Pengadilan, Hak Ingkar, Pemeriksaan Permohonan Pelaksanaan Dan Pembatalan Putusan Arbitrase sebagai pembaharuan dalam hukum arbitrase di Indonesia. Permasalahan dalam penelitian ini adalah bagaimana Pengaturan Hukum UN Model Law Mengenai Penolakan Pelaksanaan dan Pembatalan Putusan Arbitrase dan bagaimana Ketentuan Penolakan Pelaksanaan dan Pembatalan Putusan Arbitrase di Indonesia Pasca Disahkannya Peraturan Mahkamah Agung Nomor 3 Tahun 2023.  Penelitian ini menggunakan penelitian yuridis normatif, yaitu metode penelitian hukum dengan cara meneliti bahan pustaka atau bahan sekunder dengan menggunakan pendekatan perundang-undangan, komparatif, dan konseptual. Hasil penelitian ini didapati bahwa Indonesia belum mengadopsi pembatalan putusan arbitrase seperti Thailand dan Singapura yang sudah menggunakan UNCITRAL Model Law. Meski mekanismenya berbeda, ada kesamaan dalam memberikan kewenangan kepada pihak dan pengadilan terkait pembatalan. Dengan Perma 3/2023, ada penyesuaian UU 30/1999 dengan rincian tambahan mengenai penunjukan arbiter, hak penolakan, dan pembatalan putusan arbitrase. Perma 3/2023 memungkinkan penegakan putusan arbitrase sebagian, menangguhkan proses hukum untuk permohonan pembatalan, serta memperluas definisi 'ketertiban umum'.
Ekstensifikasi Penentuan Outsider Pada Pengungkapan Kejahatan Insider Trading di Pasar Modal Berdasarkan Misappropriation Theory
Authors: Alfandy Muhammad Daffa
Published: November 2024

Penyelenggaraan pasar modal harus diiringi pula oleh progresifitas pengaturan hukum melalui penciptaan regulasi berupa UU Pasar Modal yang bertujuan untuk memberikan perlindungan hukum preventif dari segala kejahatan yang potensial terjadi, salah satunya adalah perdagangan orang dalam (insider trading). Paradigma yang digunakan dalam pengaturan insider trading pada UU Pasar Modal menganut prinsip fiduciary duty. Artinya, secara konseptual, orang dalam perusahaan selaku pihak yang diberikan kepercayaan untuk menjalankan operasional perusahaan (trustee) berkewajiban untuk menjalanan kepercayaan tersebut dengan itikad baik, sehingga orang dalam tersebut tidak diperbolehkan untuk memanfaatkan kepemilikan informasi material untuk melakukan transaksi efek yang bertujuan untuk menguntungkan dirinya sendiri. Permasalahan muncul ketika prinsip fiduciary duty yang dianut oleh UU Pasar Modal tidak dapat mengungkapkan insider trading yang dilakukan oleh: (1) outsider atau tippee yang mendapatkan informasi orang dalam dari outsider atau tippee lainnya dan (2) outsider atau tippee yang mendapatkan informasi material dengan tanpa melawan hukum. Hal tersebut dikarenakan beban pembuktian pada prinsip fiduciary duty adalah keterkaitan antara pelaku dengan orang dalam pada emiten. UU Pasar Modal harus membuka ruang digunakannya misappropriation theory yang pendekatannya berorientasi pada sifat kepemilikan dari informasi material sebagaimana yang diterapkan oleh Singapura. Metode penelitian yang digunakan adalah yuridis-normatif dengan menggunakan pendekatan perundang-undangan, pendekatan perbandingan, dan pendekatan kasus. Hasil penelitian menunjukkan bahwa prinsip fiduciary duty sebagaimana termaktub dalam Pasal 95 UU Pasar Modal tidak dapat menjangkau perilaku secondary tippee dan tippee yang mendapatkan informasi tanpa melawan hukum. Oleh karena itu, Penulis berpendapat perlu dilakukannya ekstensifikasi penentuan outsider berdasarkan misappropriation theory.
O PAPEL DO FARMACÊUTICO NO CUIDADO INTEGRAL A PACIENTES PORTADORES DE HIPERTENSÃO ARTERIAL SISTÊMICA
Authors: Furtado Augusto Renildo , Sabrina Vieira Lins Francisca , Rafael Augusto Francisco , Maria de Figuerêdo Rolim Jacinta , Eduardo Ferreira Alves Francisco
Published: November 2024

A Hipertensão Arterial Sistêmica é complexa e multifatorial, no qual envolve uma associação de fatores genéticos, ambientais e comportamentais, seu diagnóstico exige uma abordagem abrangente que combine medições repetidas da pressão arterial com uma análise detalhada do histórico clínico do paciente, já seu tratamento deve ser individualizado, levando em conta as características do paciente e as diretrizes de saúde vigentes. Partindo dessa premissa ao presente artigo tem por objetivo mostrar como o farmacêutico atua de maneira abrangente, visando não apenas no controle da doença, mas na promoção do bem-estar integral dos pacientes hipertensos. Tratou-se de um estudo do tipo revisão integrativa da literatura, com abordagem qualitativa. A busca de artigos se deu nas seguintes fontes de dados: The Scientific Electronic Library Online (SciELO), Medical Literature Analysis and Retrieval System Online (MEDLINE), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). A coleta de dados se deu entre março a outubro de 2024. Os resultados mostram que a hipertensão arterial sistêmica representa um desafio significativo para a saúde pública, devido à sua alta prevalência e aos riscos associados, como complicações cardiovasculares. Foi observado que o diagnóstico precoce e a implementação de estratégias de tratamento eficazes são fundamentais para o controle adequado da pressão arterial e a redução dos impactos negativos dessa doença. Elencou-se que que o tratamento deve ser individualizado, englobando tanto terapias farmacológicas quanto medidas não farmacológicas. Conclui-se que o papel do farmacêutico é fundamental na abordagem multidisciplinar da HAS. Esse profissional atua na orientação sobre o uso correto dos medicamentos, monitorando a eficácia do tratamento e promovendo a adesão dos pacientes.

Palavras-chave: Hipertensão Arterial Sistêmica; Diagnóstico; Tratamento; Cuidado Farmacêutico.
ASSISTÊNCIA FARMACÊUTICA NO TRATAMENTO DO TRANSTORNO DO ESPECTRO AUTISTA (TEA)
Authors: Luciana Gomes Batista Jerónimo Jacia , Igor Alves Fernandes Diego , Sabrina Vieira Lins Francisca , Guilherme Galvão José , de Fátima Coelho Maria , Fabricia Pereira Ferreira Moreira Flávia
Published: November 2024

Objetivo: Este trabalho visa compreender e destacar a importância da assistência farmacêutica no acompanhamento de pacientes com TEA, utilizando uma revisão de literatura com artigos científicos publicados nas bases SciELO, PubMed, LILACS e Portal CAPES, entre 2019 e 2024. Metodologia: Para a busca foram empregados os termos "Farmacêutico (Pharmacists)", "Resultado do Tratamento (Treatment Outcome)" e "Transtorno do Espectro Autista (Autism Spectrum Disorder)", intercalados com o operador booleano "And". A pesquisa inclui estudos em português, inglês e espanhol. Resultados: Os resultados analisados reforçam que o farmacêutico, ao atuar em equipes multidisciplinares, contribui para o tratamento seguro e eficaz de crianças com TEA, especialmente no uso de medicamentos psicotrópicos. Estudos específicos, como os de Caplan et al. (2022) e Dai et al. (2021), ressaltam a importância do farmacêutico no monitoramento de efeitos adversos e na supervisão do tratamento com medicamentos como bumetanida e risperidona, que, embora eficazes, apresentam riscos metabólicos significativos, conforme destacado por Mano-Sousa et al. (2021). Além disso, os trabalhos de Silva et al. (2023) e Silvestre (2024) apontam que o farmacêutico também exerce papel educativo, orientando pacientes e seus familiares para o uso correto dos medicamentos e a adesão ao tratamento. No contexto de novos tratamentos para TEA, estudos que examinam o uso de sulforafano e mirtazapina mostram que o farmacêutico pode auxiliar na gestão de interações medicamentosas e no ajuste de dosagens, considerando as particularidades de cada paciente. Os estudos indicam que a assistência farmacêutica ajuda a minimizar riscos, aumenta a segurança e a efetividade da terapia medicamentosa, resultando em melhor qualidade de vida para os pacientes com TEA. Dada a complexidade e a variabilidade dos sintomas e comorbidades no TEA, a formação contínua e a capacitação dos farmacêuticos são indispensáveis. É fundamental também o desenvolvimento de políticas de saúde específicas que reconheçam e valorizem essa atuação. O farmacêutico, ao colaborar estreitamente com médicos, psicólogos e outros profissionais da saúde, garante que o tratamento seja holístico e focado nas necessidades individuais dos pacientes. Em suma, o papel do farmacêutico vai além da dispensação de medicamentos, sendo um agente essencial para o acompanhamento seguro e eficaz de pacientes com TEA, promovendo o uso racional de medicamentos e intervenções adequadas que contribuem para a promoção da saúde e o bem-estar desses indivíduos.

Palavras-chave: Farmacêutico, Assistência Farmacêutica, Tratamento farmacológico, Transtorno do Espectro Autista.
TERAPIA COGNITIVO-COMPORTAMENTAL NA REDUÇÃO DO USO EXCESSIVO DE TELAS DIGITAIS POR CRIANÇAS: UMA REVISÃO DE LITERATURA
Authors: Evandro da Silva Júnior José , Maria Braga Fernandes Abreu Hilana , Lúcia Pereira Costa Fernanda , Alexandre de Jesus Marques André
Published: November 2024

Introdução: Considerando a presença significativa dos meios de comunicação na rotina da maioria das crianças e adolescentes, é essencial que profissionais de saúde ofereçam orientações regulares sobre a tecnologia digital. Quando o uso de telas passa a ser considerado excessivo, requer cuidados maiores, como a possibilidade de intervenções e o acompanhamento de um profissional psicólogo. À vista disso, acredita-se que a Terapia Cognitivo-Comportamental demonstra resultados consideravelmente positivos na eficácia do tratamento. Objetivo: Investigar as consequências da exposição de crianças às telas nos seus desenvolvimentos cognitivos e como a Terapia Cognitivo-Comportamental pode contribuir como forma de intervenção. Método: Trata-se de uma revisão de literatura realizada por meio da seleção de artigos científicos publicados em periódicos indexados nas bases de dados Google acadêmico, Medical Literature Analysis and Retrieval Sistem On-line (MEDLINE) via PubMed e Biblioteca Virtual em Saúde (BVS). Foram utilizados os descritores extraídos dos Descritores em Ciências da Saúde: Tempo de Tela; Terapia Cognitivo-Comportamental; Deficiências da Aprendizagem e Desenvolvimento Infantil, através do operador booleano AND, para combinar os termos, de modo que eles correspondessem simultaneamente ao objetivo. Resultados: Foram selecionados dez estudos, dos idiomas inglês e português, publicados entre os anos 2018 e 2024. Constatou-se que exposições excessivas às telas acarretam problemas no desenvolvimento e aprendizagem das crianças. A Terapia Cognitivo-Comportamental pode contribuir para a identificação e intervenção desses problemas, pois, durante o acompanhamento psicológico, as crianças geralmente apresentam alterações no comportamento social, contribuindo para o desempenho escolar. Conclusão: Mediante os achados, fica-se notório que o uso excessivo de telas é uma problemática que tem afetado intensamente o comportamento e o desenvolvimento de crianças e jovens, e que precisam de medidas terapêuticas para amenizar o processo. Logo, a Terapia Cognitivo-Comportamental aparece como um meio de ofertar estratégias de superação para esses comportamentos disfuncionais e o desenvolvimento de hábitos mais saudáveis.

Palavras-chave: Desenvolvimento Infantil. Tempo de Tela. Terapia Cognitivo-Comportamental. Dispositivos Eletrônicos.
Abordaje trans-oral para tumores del espacio parafaríngeo: Estado del arte
Authors: Castro Sebastián , Cabezas Luis , Cardemil Felipe
Published: November 2024

Introducción: Los tumores del espacio parafaríngeo representan un desafío quirúrgico por su íntima relación con estructuras neurovasculares. Se han descrito tanto abordajes abiertos como abordajes trans-orales para su enfrentamiento, siendo este último controversial. Materiales yMétodos: Se realizó una revisión narrativa del abordaje trans-oral para tumores del espacio parafaríngeo consultando bases de datos PubMed, Scielo y Scopus, incorporando artículos en inglés y español.Discusión: El abordaje de tumores del espacio parafaríngeo es desafiante, siendo el abordaje trans-oral controversial, sin embargo con el advenimiento de nuevas tecnologías, endoscopios y cirugía robótica, su indicación se ha ampliado. El uso del abordaje trans-oral asistido con endoscopios, ha demostrado presentar un menor riesgo de sangrado, tiempo operatorio y estadía hospitalaria en comparación con abordajes abiertos, sin embargo, la evidencia que lo sustenta es de baja calidad. Aún falta mayor evidencia para generar un consenso en cuanto a las indicaciones precisas de este tipo de abordaje, no obstante, es un abordaje seguro en pacientes seleccionados.
Tratamiento quirúrgico vs manejo expectante en el hematoma retroperitoneal traumático: Una revisión sistemática y metaanálisis.
Authors: Rojas Montejo Alberto José , Gutiérrez Garatejo Angie Daniela , Suárez Alcázar María Alejandra , Collazos Torres Alejandra , Tobio Amaya Ana Yaibeth , Mendoza Ortiz Benigno
Published: November 2024

Resumen: El hematoma retroperitoneal traumático tiene una baja frecuencia de presentación y una alta tasa de mortalidad. El objetivo de esta revisión sistemática fue comparar la mortalidad, la resolución del hematoma y las complicaciones entre el tratamiento quirúrgico y el tratamiento expectante en pacientes con edad igual o mayor a 16 años. Tres estudios observacionales cumplieron con los criterios de elegibilidad. Se registró una mortalidad del 10% en el grupo quirúrgico y del 3% en el grupo conservador OR 5.22 [IC 95%: 1,34; 20,32]. La tasa de resolución fue del 85% en el grupo quirúrgico y del 98% en el grupo conservador OR 0.17 [IC 95%: 0,04; 0,66]. El tratamiento expectante tuvo una menor mortalidad y una mayor tasa de resolución del hematoma, siendo una opción adecuada en pacientes más jóvenes, con lesiones abdominales menos severas, sin inestabilidad hemodinámica y con menores requerimientos de transfusión de hemoderivados.
Caracterización funcional pre y postoperatoria de adultos sometidos a cirugía abdominal oncológica electiva
Authors: Lara Madrid Andrea , Martínez Huenchullán Sergio , Castillo Orellana Pablo , Cárcamo Gruebler Leonardo
Published: November 2024

Introducción: El cáncer es la principal causa de muerte en el mundo. En Chile, el número de muertes atribuidas al cáncer aumentó desde un 21% en 1990 hasta un 26% en 2017, siendo los cánceres de los órganos digestivos los más prevalentes en la zona sur de Chile. La cirugía está entre la primera línea de elección terapéutica para tumores resecables, provocando una disminución en la capacidad funcional. Actualmente, la literatura internacional sugiere que la intervención kinesiológica pre y postoperatoria podría mejorar la función cardiopulmonar y física del paciente disminuyendo la incidencia de complicaciones y promoviendo la independencia del individuo.Objetivo: Caracterizar la capacidad funcional pre y postoperatoria de adultos sometidos a cirugía oncológica radical digestiva luego de una intervención kinesiológica estandarizada en un hospital público de alta complejidad de la zona sur de Chile.Materiales y Método:  Estudio de cohorte concurrente que incluyó 29 pacientes candidatos a cirugía digestiva radical oncológica. Se registraron los antecedentes sociodemográficos, clínicos y las variables funcionales como capacidad aeróbica (test de marcha en 6 minutos), desempeño físico general (short performance battery test), fuerza de presión manual y fuerza muscular respiratoria.Resultados: Existió una disminución significativa en relación al peso y funcionalidad postoperatoria (p<0,05) respecto al prequirúrgico. En cuanto a la fuerza muscular espiratoria y la capacidad aeróbica, ambas presentaron disminuciones significativas (p<0,01).Conclusión: A pesar de recibir un protocolo estándar de movilización precoz, los pacientes sometidos a cirugía abdominal oncológica electiva presentaron un deterioro en funcionalidad, capacidad aeróbica y fuerza muscular respiratoria.
Complicaciones biliares postrasplante hepático en una institución de Colombia
Authors: Tarazona Leon Cristian , Vanegas Ballesteros Mauricio , Alejandro Vergara Fabio , Camelo Pardo Gianmarco , Manrique Hernandez Edgar Fabian
Published: November 2024

Introducción: Las complicaciones biliares posterior al trasplante ortotópico de hígado son las complicaciones más importantes y frecuentes, relacionándose directamente con mortalidad, disfunción del injerto y aumento estancia hospitalaria.Objetivo: El objetivo de este estudio es caracterizar los pacientes que presentaron complicaciones biliares posterior a trasplante hepático, entendiendo que es una entidad con alta morbi-mortalidad, siendo crucial la detección temprana, sospecha clínica y tratamiento.Materiales y Métodos: Estudio transversal, retrospectivo y observacional, con seguimiento a 82 pacientes sometidos a trasplante hepático en la Fundación Cardiovascular entre el año 2013 al año 2023, seleccionando quienes presentaron complicaciones biliares post quirúrgicas. Se evaluó el tipo de complicación, factores de riesgo y desenlaces postquirúrgicos. Resultados: Existio un predominio del sexo masculino 59,76% (n=49) en la totalidad de los pacientes trasplantados siendo la principal indicacion el alcoholismo (21,95%). Un total de 28 pacientes presentaron complicaciones del árbol biliar. La principal complicación fue la estenosis anastomosis con 50%. Conclusión: Las complicaciones biliares son una entidad relacionada con morbilidad, sin embargo, generalmente presentan menores desenlaces fatales en relación a las complicaciones vasculares. Es importante la sospecha y diagnóstico con respectiva intervención.
Pares Revisores 2024
Authors: Yarmuch Gutierrez Julio
Published: November 2024

En este documento se expresan agradecimientos y se menciona a los pares revisores de artículos publicados en la Revista de Cirugía durante el año 2024.
ANALISIS PENGARUH KUALITAS PELAYANAN BERBASIS BUDAYA ORGANISASI TERHADAP KEPUASAN PENGGUNA JASA FASILITAS KAWASAN BERIKAT PADA BEA CUKAI MAGELANG
Authors: Wardana Subroto Wisnu , Wulandari Florentina Ratih , Nugroho Rino Ardhian
Published: November 2024

The aim of the research is to examine, determine and analyze the influence of service quality based on organizational culture on the satisfaction of users of Bonded Zone facility services at Magelang Customs. The method used is a quantitative method with a descriptive statistical approach. Research data at Magelang Customs. was obtained using a questionnaire and a sample of 49 respondents. The data analysis carried out in the research is statistical and mathematical methods through GAP Analysis, Customer Satisfaction Index (CSI), and Importance-Performance Analysis (IPA) measurements. The results of research on Service Quality calculations using GAP Analysis show that there are indicators from statement items that have negative values from the GAP Analysis calculations for each dimension of service quality with the total score obtained being -0.20. This value shows that the expectation score is greater than the performance score. Data analysis using the Customer Satisfaction Index (CSI) at Magelang Customs showed that 89.12% were very satisfied. The overall level of customer satisfaction by looking at the level of performance and level of importance of product or service attributes as measured using the Customer Satisfaction Index (CSI) at the Magelang Customs, overall expectations and performance are very good. Then, the results of the Importance-Performance Analysis (IPA) measurement show improvements in service quality which are focused on 5 indicators that are included in important services, but satisfaction is still low.
Antihyperglycemic Effect of Gymnema inodorum in Type 2 Diabetes Management
Authors: Kongcharoen Watis , Jaturaporn Ananya , Chavalit Kittisak , Charoensup Nathirat
Published: November 2024

This study investigates the antihyperglycemic effects of Gymnema inodorum (Chiang Da), a traditional medicinal plant from northern Thailand, commonly used for managing blood glucose levels. The goal was to evaluate its pharmacological effects, including the inhibition of alpha-glucosidase and its ability to lower blood glucose levels in Type 2 diabetic rats. Ethanol maceration was used to extract bioactive compounds from Chiang Da leaves, yielding gymnemic acids, saponins, and flavonoids. The in vivo study involved administering Chiang Da tea to diabetic rats for 8 weeks, measuring fasting and postprandial blood glucose levels. Results showed a significant reduction in blood glucose levels in the Chiang Da-treated group, comparable to the synthetic drug metformin. In vitro tests also revealed the extract’s concentration-dependent inhibition of alpha-glucosidase, with an IC50 value of 45 µg/mL, indicating moderate potency in delaying glucose absorption. Descriptive and inferential statistics confirmed that Chiang Da tea significantly reduced blood glucose levels, though its effects were less pronounced than metformin’s. These findings support the potential of Chiang Da as a natural alternative for managing Type 2 diabetes, particularly for individuals seeking plant-based treatments. Future research should focus on clinical trials to further evaluate the efficacy and safety of Chiang Da for diabetes management, as well as explore its potential for combination therapy with conventional drugs to enhance therapeutic outcomes.
Pharmacological Evaluation of Sambong Blumea balsamifera on Diuretic and Kidney Stone Dissolution Effects
Authors: Jose Stefhene , Garcia Maria , Lopez Juan , Reyes Ana , Cruz Luis
Published: November 2024

This study investigates the pharmacological effects of Blumea balsamifera (Sambong), a plant traditionally used in Filipino medicine for its diuretic and kidney stone-dissolving properties. Using Soxhlet and maceration extraction methods, Sambong extracts were obtained from the leaves and roots of the plant with ethanol as the solvent. Phytochemical analysis revealed bioactive compounds including flavonoids (luteolin, quercetin) and terpenoids (β-caryophyllene), known for their anti-inflammatory, antioxidant, and diuretic effects. The diuretic activity was tested in rats, where Sambong extracts (50 mg/mL and 100 mg/mL) were administered and the urine output was measured over 24 hours. The results showed a dose-dependent increase in urine output, with the 100 mg/mL dose producing a significant increase compared to the control group treated with furosemide. In addition to its diuretic effects, Sambong’s potential to dissolve kidney stones was evaluated by treating rats with calcium oxalate stones. The results indicated a significant reduction in stone size, with the 100 mg/mL dose achieving a 38% reduction. The comparative analysis with furosemide demonstrated that Sambong is a promising natural alternative for managing conditions such as hypertension, kidney stones, and urinary disorders, particularly in areas with limited access to pharmaceutical treatments. These findings validate Sambong’s traditional uses and highlight its therapeutic potential in modern healthcare. Future research should focus on clinical trials to assess its safety, optimal dosage, and efficacy in humans. Further investigation into its pharmacological mechanisms, including its anti-inflammatory and antimicrobial properties, could expand its use in treating various conditions, integrating Sambong into contemporary healthcare systems, especially in underserved areas.
Participation of Athonite Monks in church and cultural processes in the 17th century Polish-Lithuanian Commonwealth territorie
Authors: Shumylo Serhii
Published: November 2024

The article studies the participation of Athonite monks in the church and cultural life of the Ukrainian-Belarusian lands in the Polish-Lithuanian Commonwealth from the end of the 16th century onwards into and during the 17th centuries. Attention is drawn to the participation of Athonite clergy in literacy, educational and other activities after the tragic events of the Union of Brest. Evidence for the stay of the Ukrainian monk and polemicist Ivan Vyshenskyi in the Zograf Monastery on Mount Athos is an early printed book issued in 1595 kept at the monastery library, which contains a gift inscription by Vasyl Surozhskyi to Ivan Vyshenskyi. The presence of archimandrite Leontii, the abbot of the Peresopnytsia Monastery, who also spent some time there, is confirmed by remarks in several early printed books from the Zograf library. A considerable number of Ukrainian-Belarusian early printed books from the 16th and 17th centuries, preserved in the libraries of Zograf, Hilandar and other Athonite monasteries, attest to their close contacts with the clergy and monks of the Kyiv Metropolis during this period. The tradition of Athonite participation in the spiritual, cultural, and political life of Ukraine and the Ukrainian Cossacks gradually became a well-established practice from the 17th century onwards. This, in turn, contributed to the intensification of spiritual and cultural life in the Ukrainian-Belarusian lands, the revival of Orthodoxy and monasticism, and the restoration of ties between the Orthodox of the Polish-Lithuanian Commonwealth and the Holy Mount Athos and the Orthodox world.
Prawosławna teologia polityczna i politologia – charakterystyka z perspektywy doktryny prawosławnej
Authors: Ławreszuk Marek
Published: November 2024

Niniejszy artykuł koncentruje się na przedstawieniu definicji i wskazaniu zasadniczych różnic między istniejącymi w naukowych opracowaniach określeniami prawosławna teologia polityczna oraz politologia prawosławna. Oba charakteryzują subdyscypliny naukowe, w których możemy poszukiwać odpowiedzi na pytanie o relacje Cerkwi ze społeczeństwem, stosunek do modeli politycznych oraz wydarzeń o charakterze globalnym, w tym do wojen i konfliktów politycznych. Systematyzacja pojęć pozwala na próbę przedstawienia właściwego obszaru i metodologii badań. Wnioski skupiają się wokół postulatów precyzji terminologicznej i wyznaczenia właściwego obszaru badawczego, co pozwoli na przyjęcie odpowiedniej metodologii analizy i rozwiązywania problemów w relacji Cerkwi ze światem społeczno-politycznym. Prawidłowa metodologia pozwoli zaś na dalszą drogę poszukiwania odpowiedzi i argumentów w dyskusjach dotyczących kwestii ogólnospołecznych, politycznych lub światopoglądowych.
Pengembangan Buku Saku Biologi Berbasis Model ADDIE untuk Meningkatkan Minat Baca Siswa
Authors: Naja Faizatun , Haikal Moch. , Fathir Akhmad , Antika Linda Tri
Published: November 2024

Pengembangan bahan ajar yang inovatif dan menarik sangat penting dalam meningkatkan minat belajar siswa. Penelitian ini bertujuan untuk mengembangkan dan menguji buku saku biologi berbasis model ADDIE yang praktis dan menarik bagi siswa kelas XI SMA. Metode yang digunakan adalah Research and Development (R&D) dengan model ADDIE, yang melibatkan tahapan analisis kebutuhan, perancangan, pengembangan, implementasi, dan evaluasi. Produk akhir divalidasi oleh ahli materi dan media, serta diuji pada kelompok siswa melalui desain One Group Pretest-Posttest. Hasil validasi menunjukkan bahwa buku saku memiliki kelayakan yang baik dengan skor 78% dari ahli materi dan 73% dari ahli media. Uji coba pada siswa menunjukkan peningkatan signifikan dalam minat baca, dengan skor rata-rata meningkat dari 16,5 menjadi 25,1 (p < 0,001). Temuan ini menunjukkan bahwa buku saku biologi berbasis model ADDIE efektif dalam meningkatkan minat baca siswa. Buku saku ini diharapkan menjadi bahan ajar alternatif yang mendukung pembelajaran mandiri dan meningkatkan keterlibatan siswa dalam proses belajar.
Development of an ADDIE-Based Biology Pocket Book to Enhance Reading Interest among Eleventh-Grade High School Students
Abstract
Innovative and engaging instructional materials are crucial in enhancing students’ interest in learning. This study aimed to develop and evaluate an ADDIE-based biology pocket book designed to be practical and appealing for eleventh-grade high school students. The Research and Development (R&D) approach was applied using the ADDIE model, encompassing need analysis, design, development, implementation, and evaluation. The final product was validated by subject and media experts and tested on a group of students using a One Group Pretest-Posttest design. Validation results indicated high feasibility with scores of 78% from the subject expert and 73% from the media expert. Testing on students showed a significant increase in reading interest, with the average score rising from 16.5 to 25.1 (p < 0.001). These findings suggest that the ADDIE-based biology pocket book effectively enhances students’ reading interest. The pocket book is expected to serve as an alternative instructional material that supports independent learning and boosts student engagement in the learning process.
The Impact of PhET-Assisted Problem-Solving Model on Enhancing Students' Physics Problem-Solving Skills in Indonesian High Schools
Authors: Harudu La , Nursalam La Ode , Kasmiati Sitti , Hasan Sakka , Sugiarto Agus , Karim Ahmad Tarmizi Abdul , Syarifuddin S. , Sejati Andri Estining
Published: November 2024

This study investigates the impact of a PhET-assisted problem-solving model on high school students' physics problem-solving skills, especially in resource-limited educational settings in Indonesia. Conducted as a quasi-experimental study with a non-equivalent control group pretest-posttest design, the research involved 50 students from SMAN 10 Kendari, divided into an experimental group receiving instruction through the PhET-assisted model and a control group following traditional teaching methods. The intervention consisted of structured learning sessions incorporating PhET simulations, designed to engage students actively with physics concepts through virtual experiments. Data were collected using a 10-item problem-solving test and analyzed using a one-way ANOVA to determine the statistical significance of differences in performance between groups. Results revealed a significant improvement in the experimental group, with a mean increase of 47.91 points from pretest to posttest (M = 83.54, SD = 15.22) compared to the control group’s improvement of 39.11 points (M = 74.48, SD = 12.78). The ANOVA results (F = 23.526, p < 0.001) confirm that the PhET-assisted model significantly enhanced students' problem-solving skills. These findings suggest that PhET simulations can be an effective tool for improving physics learning outcomes in schools with limited access to laboratory resources. Integrating PhET simulations into the physics curriculum could provide students with accessible, interactive learning experiences that bridge the gap in traditional laboratory access, fostering a deeper understanding and application of physics concepts.
Calidad de vida en pacientes post amputación de miembros inferiores
Authors: Peralta España Jorge Mario
Published: November 2024

OBJETIVO: Describir la calidad de vida en pacientes post amputados de miembros inferiores mediante cuestionario de salud SF-36. MÉTODO: Se realizó un estudio descriptivo prospectivo transversal, donde se entrevistaron 56 pacientes post amputados de miembros inferiores mediante cuestionario de salud SF-36. RESULTADOS: Se demostró que la calidad de vida según el cuestionario de salud SF-36 fue una calidad de vida alta en 21 pacientes (37%), seguido de una calidad de vida promedio en 20 pacientes (36%) y una calidad de vida baja en 11 pacientes (20%). El grupo etario más afectado fue de 60 a 74 años, con un total de 29 pacientes (52%). Así mismo, se identificó que el sexo más afectado fue el femenino con un total de 31 pacientes (55%). CONCLUSIÓN: Los resultados mostraron que un 37% de los pacientes reportaron una calidad de vida alta, seguido de un 36% con un nivel promedio, indicando que más de dos tercios de los participantes presentan un bienestar satisfactorio. No obstante, un 20% experimentó una calidad de vida baja y un 7% muy baja, lo que resalta la necesidad de intervenciones específicas de apoyo para este grupo más vulnerable. El grupo etario más afectado fue de 60 a 74 años con un 52%, lo cual indica la necesidad de enfatizar dinámicas dirigidas a la prevención de las enfermedades metabólicas, las cuales son la principal causa de amputaciones en este grupo etario.
Implicature in Selected News Bulletin of Radio Kogi
Authors: Samson Precious Funke , Olajimbiti Ezekiel , Ejiako Maryjane Ogechi , Chinwenmeri Emeghara Jael , Ogechkwu Ochuba Victor , Ebe Uchenna Prince , William Blessing Wellington
Published: November 2024

Previous studies on implicature have addressed many areas with the exclusion of implicature in news bulletins on radio which accounts for how the media use language. This becomes the focus of this study as it examines how the media use language in news bulletins by looking at the types of implicature in the discourse, the instances of implicature, contextual frames, and their implication on the listeners. H.P Grice’s Theory of Implicature (1975) was employed in the analysis of the sampled data. A total number of 12 news bulletins with 250 news items were collected from Radio Kogi Studio in Lokoja between January – February 2021. The researcher found 34 utterances containing implicature in the news bulletin, a total number of 17 utterances were analyzed, 6 utterances under the two types of implicature, and 6 utterances flouted the cooperative principles. The implication of the instances of implicature found in this study shows that the audience would need more inference to understand or comprehend what the news is all about. If not some of them could be misleading because they are ambiguous, obscure, and sometimes, lack enough evidence.
Overview of the Factors Influencing the Efficiency of PV Solar Cells
Authors: Almedhem Adel M.
Published: November 2024

PV technology works through the direct conversion of sunlight into electricity, a process based on the photoelectric effect. This phenomenon happens when specific materials absorb light particles, leading to the release of electrons. Capturing these electrons produces an electric current. Which can be harnessed as usable electricity. The development of more efficient PV system designs and enhancements in their operation and maintenance are key areas of current innovation. These advances are crucial for improving the overall performance and sustainability of solar energy systems, making them a more viable and dependable option for future energy needs. In the literature there are plenty of papers on solar energy, in order to advance the research on this subject we needs up to date information on the current situation. As such is lacking at present, A current literature review of this phenomenon is reffered for more detail.