bluuebunny/crossref_metadata_2025 huggingface dataset:
“I have just returned from the moon:” online survey fraud
Authors: Brazhkin Vitaly
Published: March 2020

Purpose

The purpose of this paper is to provide a comprehensive review of the respondents’ fraud phenomenon in online panel surveys, delineate data quality issues from surveys of broad and narrow populations, alert fellow researchers about higher incidence of respondents’ fraud in online panel surveys of narrow populations, such as logistics professionals and recommend ways to protect the quality of data received from such surveys.

Design/methodology/approach

This general review paper has two parts, namely, descriptive and instructional. The current state of online survey and panel data use in supply chain research is examined first through a survey method literature review. Then, a more focused understanding of the phenomenon of fraud in surveys is provided through an analysis of online panel industry literature and psychological academic literature. Common survey design and data cleaning recommendations are critically assessed for their applicability to narrow populations. A survey of warehouse professionals is used to illustrate fraud detection techniques and glean additional, supply chain specific data protection recommendations.

Findings

Surveys of narrow populations, such as those typically targeted by supply chain researchers, are much more prone to respondents’ fraud. To protect and clean survey data, supply chain researchers need to use many measures that are different from those commonly recommended in methodological survey literature.

Research limitations/implications

For the first time, the need to distinguish between narrow and broad population surveys has been stated when it comes to data quality issues. The confusion and previously reported “mixed results” from literature reviews on the subject have been explained and a clear direction for future research is suggested: the two categories should be considered separately.

Practical implications

Specific fraud protection advice is provided to supply chain researchers on the strategic choices and specific aspects for all phases of surveying narrow populations, namely, survey preparation, administration and data cleaning.

Originality/value

This paper can greatly benefit researchers in several ways. It provides a comprehensive review and analysis of respondents’ fraud in online surveys, an issue poorly understood and rarely addressed in academic research. Drawing from literature from several fields, this paper, for the first time in literature, offers a systematic set of recommendations for narrow population surveys by clearly contrasting them with general population surveys.
How do personality traits affect visitor’s experience, emotional stimulation and behaviour? The case of wine tourism
Authors: Leri Ifigeneia , Theodoridis Prokopis
Published: March 2020

Purpose

The purpose of this study is to investigate the moderation effects of the Big Five personality traits on the relationships between holistic experience constructs (i.e. servicescape and other visitors’ behaviours), emotional responses and revisit intention in the context of winery visitation experiences in Greece.

Design/methodology/approach

The study adopts a holistic approach to visitor experience and suggests that visitors base their experience perception on the servicescape’s attributes and other visitors’ suitable behaviours. Path analysis was adopted to measure the impact of these constructs on visitors’ emotions and the role these emotions play in predicting visitors’ revisit intentions. The moderation effect of the Big Five personality traits in such relationships was examined using the SPSS PROCESS. A self-administered, highly structured questionnaire was distributed to winery visitors in Greece; a total of 615 responses were used in data analysis.

Findings

The results indicate that all the examined relationships become stronger as a result of visitors having high or average scores for openness, extraversion, agreeableness and conscientiousness, or low scores for neuroticism.

Research limitations/implications

The findings enhance the existing literature pertaining to experiential marketing, wine tourism marketing and the role of personality in tourism by providing new insights.

Practical implications

The overall findings may benefit wineries in their efforts to carry out the following: increase visitors’ revisit intentions; design and manage the winery environment and the winery experience effectively; and design marketing strategies.

Originality/value

The paper’s originality lies in providing information to clarify the role of visitors’ personalities as a contributing factor to their emotional stimulation and their revisit intentions in terms of both constructs of experience (i.e. servicescape and other visitors’ behaviours). Furthermore, this study attempts to respond to recent calls to conduct multidimensional research on the servicescape construct, focusing on both the substantive staging of the servicescape and the communicative staging of the servicescape. Finally, the present study provides new and practical insights regarding the winery experience in the Greek context – an area where very limited research has been conducted so far.
Carer burden and positive gain in dementia
Authors: George Catriona , Ferreira Nuno
Published: March 2020

Purpose

Behavioural and psychological symptoms of dementia (BPSD) have been well established as factors involved in the development of carer burden. However, it is not clear which symptoms are most burdensome for carers and which caregiver factors may be involved. This study aims to explore symptoms associated with executive functioning deficits and their impact on three dimensions of carer burden and positive gain. It also aims to discover whether behaviour management strategies used by carers, and their level of experiential avoidance, had an independent impact on these factors.

Design/methodology/approach

A total of 110 dementia caregivers completed five self-report measures as part of a cross-sectional design: the Dysexecutive Questionnaire (DEX), Zarit Burden Interview, Positive Aspects of Caregiving Questionnaire, Dementia Management Strategies Scale and Experiential Avoidance in Caregiving Questionnaire (EACQ).

Findings

Executive functioning deficits (DEX) were found to account for most variance in burden, with DEX subscales impacting differentially on the three dimensions of burden and positive gain. The use of negative management strategies was associated with higher levels of burden, as was Active Avoidant Behaviour (a subscale of the EACQ), whereas positive management strategies were associated with positive gain.

Originality/value

In line with previous findings, symptoms associated with executive functioning deficits were the most significant factor in the development of carer burden. The findings relating to behaviour management strategies and experiential avoidance suggest that these could be potential mediating mechanisms in this relationship. Further research is required to explore this in detail, and to consider implications for targeted carer interventions.
Opposing fitness consequences of habitat use in a harvested moose population
Authors: Ofstad Endre Grüner , Markussen Stine S. , Sæther Bernt‐Erik , Solberg Erling J. , Heim Morten , Haanes Hallvard , Røed Knut H. , Herfindal Ivar
Published: March 2020

Landscape changes are happening at an unprecedented pace, and together with high levels of wildlife harvesting humans have a large effect on wildlife populations. A thorough knowledge of their combined influence on individual fitness is important to understand factors affecting population dynamics.

The goal of the study was to assess the individual consistency in the use of risky habitat types, and how habitat use was related to fitness components and life‐history strategies.

Using data from a closely monitored and harvested population of moose Alces alces, we examined how individual variation in offspring size, reproduction and survival was related to the use of open grasslands; a habitat type that offers high‐quality forage during summer, but at the cost of being more exposed to hunters in autumn. The use of this habitat type may therefore involve a trade‐off between high mortality risk and forage maximization.

There was a high repeatability in habitat use, which suggests consistent behaviour within individuals. Offspring number and weight were positively related to the mothers' use of open grasslands, whereas the probability of surviving the subsequent harvest season was negatively related to the use of the same habitat type. As a consequence, we found a nonsignificant relationship between habitat use and lifetime fitness.

The study suggests that harvesting, even if intended to be nonselective with regard to phenotypes, may be selective towards animals with specific behaviour and life‐history strategies. As a consequence, harvesting can alter the life‐history composition of the population and target life‐history strategies that would be beneficial for individual fitness and population growth in the absence of hunting.
Anti‐elite politics and emotional reactions to socio‐economic problems: Experimental evidence on “pocketbook anger” from France, Germany, and the United States
Authors: Marx Paul
Published: March 2020

Many observers have noticed the importance of anger in contemporary politics, particularly with reference to populism. This article addresses the question under which conditions people become angry about a specific aspect of their lives: their personal financial situation. Specifically, it asks if populist anti‐elite rhetoric has a causal influence on anger and if this influence differs across socio‐economic groups. The theoretical expectation is that anti‐elite rhetoric allows people to externalize responsibility for an unfavorable financial situation and thereby to turn negative self‐conscious emotions into anger. The argument is tested with original survey data from France, Germany, and the United States. The empirical analysis yields three main insights. First, negative emotional reactions to respondents’ personal finances (and anger in particular) are surprisingly widespread in all three countries. Second, there is a pronounced socio‐economic gradient in the distribution of anger and other negative emotions. Third, and most importantly, randomly exposing participants to populist anti‐elite rhetoric causes considerably higher expressed anger about one's financial situation in France and Germany, but less so in the United States. This suggests a causal role of anti‐elite rhetoric in stirring “pocketbook anger.” This is true in particular in the middle classes. The notion that populist rhetoric reduces negative self‐conscious emotions, such as shame, is not supported by the data.
Isolation of novel ACE‐inhibitory peptide from naked oat globulin hydrolysates in silico approach: Molecular docking, in vivo antihypertension and effects on renin and intracellular endothelin‐1
Authors: Zheng Yajun , Wang Xian , Zhuang Yongliang , Li Yan , Shi Panqi , Tian Hailong , Li Xiaotian , Chen Xing
Published: March 2020

Naked oat globulin was hydrolyzed by alcalase, flavourzyme, pepsin, and trypsin in sequence. The hydrolysates (NOGH) were purified using gel chromatography, reversed‐phase high performance liquid chromatography (RP‐HPLC). Finally, fraction D7d with the highest ACE‐inhibitory was subjected to liquid chromatography‐mass spectrometry analysis and 14 peptides were identified. Of which, peptide SSYYPFK (890.4 Da) was chose to synthesize based on in silico analysis. The SSYYPFK demonstrated high ACE‐inhibitory activity (IC50: 91.82 µM) with competitive inhibition mode, and could effectively (P < 0.05) lower the systolic blood pressure and diastolic pressure of spontaneously hypertensive rats at the concentration of 100 to 150 mg/kg body weight. Molecular docking simulation demonstrated that SSYYPFK could bind with the active site S1 of ACE via short hydrogen bonds. It could remain the ACE‐inhibitory activity after simulated gastrointestinal hydrolysis. Moreover, SSYYPFK showed acceptable renin and endothelin‐1 suppressing capacity (47.59% and 27.88% at 1.5 mg/mL, respectively). These results indicated that SSYYPFK may have similar antihypertensive mechanism with captopril, and could be develop to natural antihypertensive products.

Practical Application

One novel ACE‐inhibitory peptide SSYYPFK (890.4 Da) was identified from naked oat globulin hydrolysates. It exhibited relatively high renin and intracellular endothelin‐1 suppressing capacity, and could effectively (P < 0.05) lower the systolic blood pressure and diastolic pressure of spontaneously hypertensive rats. This peptide could be used as natural and safe nutraceuticals and/or functional ingredients.
Chromosome‐level genome assembly of the greenhouse whitefly (Trialeurodes vaporariorum Westwood)
Authors: Xie Wen , He Chao , Fei Zhangjun , Zhang Youjun
Published: March 2020

The greenhouse whitefly, Trialeurodes vaporariorum Westwood, is an agricultural pest of global importance. Here we report a 787‐Mb high‐quality draft genome sequence of T. vaporariorum assembled from PacBio long reads and Hi‐C chromatin interaction maps, which has scaffold and contig N50 lengths of 70 Mb and 500 kb, respectively, and contains 18,275 protein‐coding genes. About 98.8% of the assembled contigs were placed onto the 11 T. vaporariorum chromosomes. Comparative genomic analysis reveals significantly expanded gene families such as aspartyl proteases in T. vaporariorum compared to Bemisia tabaci Mediterranean (MED) and Middle East‐Asia Minor 1 (MEAM1). Furthermore, the cytochrome CYP6 subfamily shows significant expansion in T. vaporariorum and several genes in this subfamily display developmental stage‐specific expression patterns. The high‐quality T. vaporariorum genome provides a valuable resource for research in a broad range of areas such as fundamental molecular ecology, insect–plant/insect–microorganism or virus interactions and pest resistance management.
Provider Perspectives on the Use of Evidence‐based Risk Stratification Tools in the Evaluation of Pulmonary Embolism: A Qualitative Study
Authors: Westafer Lauren M. , Kunz Ashley , Bugajska Patrycja , Hughes Amber , Mazor Kathleen M. , Schoenfeld Elizabeth M. , Stefan Mihaela S. , Lindenauer Peter K.
Published: March 2020

Objectives

Providers often pursue imaging in patients at low risk of pulmonary embolism (PE), resulting in imaging yields <10% and false‐positive imaging rates of 10% to 25%. Attempts to curb overtesting have had only modest success and no interventions have used implementation science frameworks. The objective of this study was to identify barriers and facilitators to the adoption of evidence‐based diagnostic testing for PE.

Methods

We conducted semistructured interviews with a purposeful sample of providers. An interview guide was developed using the implementation science frameworks, consolidated framework for implementation research, and theoretical domains framework. Interviews were recorded, transcribed, and analyzed in an iterative process. Emergent themes were identified, discussed, and organized.

Results

We interviewed 23 providers from four hospital systems, and participants were diverse with regard to years in practice and practice setting. Barriers were predominately at the provider level and included lack of knowledge of the tools, particularly misunderstanding of the validated scoring systems in Wells, as well as risk avoidance and need for certainty. Barriers to prior implementation strategies included the perception of a clinical decision support (CDS) tool for PE as adding steps with little value; most participants reported that they overrode CDS interventions because they had already made the decision. All providers identified institution‐level strategies as facilitators to use, including endorsed guidelines, audit feedback with peer comparison about imaging yield, and peer pressure.

Conclusions

This exploration of the use of risk stratification tools in the evaluation of PE found that barriers to use primarily exist at the provider level, whereas facilitators to the use of these tools are largely perceived at the level of the institution. Future efforts to promote the evidence‐based diagnosis of PE should be informed by these determinants.
Opioid‐induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial
Authors: Abril Ochoa Lorena , Naeem Farnia , White Deborah J. , Bijur Polly E. , Friedman Benjamin W.
Published: March 2020

Background

Parenteral opioids are commonly used to treat acute severe pain. We measured pleasurable sensations in patients administered intravenous analgesics to determine if these sensations were associated with receipt of an opioid, after controlling for relief of pain. Pleasurable sensations not accounted for by relief of pain were considered opioid‐induced euphoria.

Methods

These data were from a randomized study of 1 mg of hydromorphone versus 120 mg of lidocaine for abdominal pain. To assess euphoria, participants were asked to provide a 0 to 10 response to each of these questions: 1) How good did the medication make you feel? 2) How high did the medication make you feel? and 3) How happy did the medication make you feel? Pain at baseline and 30 minutes was also measured on a 0 to 10 scale. To determine the relative importance of pain relief versus medication type, we built three linear regression models in which each euphoria question was the dependent variable and pain relief, medication type, and medication‐induced side effects were the independent variables.

Results

Seventy‐seven patients received lidocaine and 77 hydromorphone. Hydromorphone patients reported greater pain improvement than lidocaine patients (mean difference = 1.5, 95% confidence interval [CI] = 0.6 to 2.3) and higher scores on all three euphoria questions (“feeling good” difference = 1.9, 95% CI = 0.8 to 3.0; “feeling high” difference = 1.5, 95% CI = 0.4 to 2.7; “feeling happy” difference = 1.7, 95% CI = 0.6 to 2.8). In the regression models, hydromorphone administration (β‐coefficient = 0.16, p = 0.03) and pain relief (β‐coefficient = 0.45, p < 0.01) were both associated with “feeling good.” “Feeling high” and “feeling happy” were associated with pain improvement (p < 0.01) but not with hydromorphone administration (p = 0.07 for “high” and p = 0.06 for “happy”). Medication‐induced side effects were not associated with these measures of euphoria.

Conclusion

Among emergency department patients with acute pain, hydromorphone‐induced euphoria, though measurable, was generally less important for patients than relief of pain.
Daily Ethanol Drinking Followed by an Abstinence Period Impairs Bone Marrow Niche and Mitochondrial Function of Hematopoietic Stem/Progenitor Cells in Rhesus Macaques
Authors: Varlamov Oleg , Bucher Matthew , Myatt Leslie , Newman Natali , Grant Kathleen A.
Published: March 2020

Background

Unhealthy consumption of alcohol is a major public health crisis with strong associations between immunological dysfunctions, high vulnerability to infectious disease, anemia, and an increase in the risk of hematological malignancies. However, there is a lack of studies addressing alcohol‐induced changes in bone marrow (BM) and hematopoiesis as fundamental aspects of immune system function.

Methods

To address the effect of chronic alcohol consumption on hematopoietic stem and progenitor cells (HSPCs) and the BM niche, we used an established rhesus macaque model of voluntary alcohol drinking. A cohort of young adult male rhesus macaques underwent a standard ethanol self‐administration protocol that allowed a choice of drinking alcohol or water 22 hours/day with periods of forced abstinence that elevated subsequent intakes when alcohol availability resumed. Following the last month of forced abstinence, the monkeys were euthanized. HSPCs and bone samples were collected and analyzed in functional assays and by confocal microscopy.

Results

HSPCs from alcohol animals exhibited reduced ability to form granulocyte–monocyte and erythroid colonies in vitro. HSPCs also displayed a decrease in mitochondrial oxygen consumption linked to ATP production and basal respiratory capacity. Chronic alcohol use led to vascular remodeling of the BM niche, a reduction in the number of primitive HSPCs, and a shift in localization of HSPCs from an adipose to a perivascular niche.

Conclusions

Our study demonstrates, for the first time, that chronic voluntary alcohol drinking in rhesus macaque monkeys leads to the long‐term impairment of HSPC function, a reduction in mitochondrial respiratory activity, and alterations in the BM microenvironment. Further studies are needed to determine whether these changes in hematopoiesis are persistent or adaptive during the abstinent period and whether an initial imprinting to alcohol primes BM to become more vulnerable to future exposure to alcohol.
Early Ethanol Exposure Inhibits the Differentiation of Hippocampal Dentate Gyrus Granule Cells in a Mouse Model of Fetal Alcohol Spectrum Disorders
Authors: Xu Wenhua , Li Hui , He Caigu , Frank Jacqueline , Chen Gang
Published: March 2020

Background

Alcohol consumption during pregnancy may damage the developing central nervous system of the fetus and lead to brain structural and functional deficits in the children, known as fetal alcohol spectrum disorders. The underlying mechanisms have not been fully elucidated. Previously, using a third trimester–equivalent mouse model, ethanol (EtOH)‐induced behavioral deficits (including spatial learning and memory dysfunction) in the mice were detected on postnatal day (PD) 35. The hippocampal formation is critically involved in spatial learning/memory and contains 2 major neuron populations: the pyramidal cells in the hippocampus proper and the dentate gyrus granule cells (DGGCs) in the dentate gyrus (DG). In rodents, while the pyramidal cells are almost exclusively generated prenatally, the DG granule neurons are majorly generated during the first 2 weeks postnatally, which coincides with the period of EtOH exposure in our mouse model. Therefore, in the current study the effects of EtOH exposure on the development of the DGGCs were examined.

Methods

C57BL/6 mice were treated with 4 g/kg of EtOH by intubation on PD 4 to 10 to mimic alcohol exposure to the fetus during the third trimester in humans, and the development of DGGCs was examined by immunohistochemistry and quantified on PD 35.

Results

EtOH exposure does not affect the number of total or newly generated DGGCs, but reduces the number of mature DGGCs on PD 35 in both male and female mice. The ratio of immature DGGCs over total DGGCs was increased, and the ratio of mature DGGCs over total DGGCs was decreased by EtOH exposure. In addition, no sex‐dependent effects of EtOH treatment were detected.

Conclusion

Our data indicate that EtOH exposure in mice during PD 4 to 10 does not affect the generation/proliferation but inhibits the differentiation of the DGGCs on PD 35.
Association of Cannabis Use With Intimate Partner Violence Among Couples With Substance Misuse
Authors: Flanagan Julianne C. , Leone Ruschelle M. , Gilmore Amanda K. , McClure Erin A. , Gray Kevin M.
Published: March 2020

Background and Objectives

There is a well‐established causal link between substance use and intimate partner violence (IPV) perpetration and victimization. However, little is known about the complex emerging relationship between cannabis use and IPV. Because cannabis is the most commonly used drug in the United States and is associated with numerous IPV risk factors such as alcohol use, it is important to examine this relationship in greater detail.

Method

The current exploratory study examined the association between (a) self‐reported cannabis use during the past 90 days and (b) Δ9‐tetrahydrocannabinol (THC) urine drug screens and IPV perpetration and victimization in a sample of 30 alcohol or drug‐misusing community couples (N = 60 individual participants).

Results

The majority of participants (n = 50 individuals, 83.3%) had concordant cannabis self‐reported and urine drug screen results. After accounting for demographic variables and quantity and frequency of alcohol and stimulant use, greater quantity and frequency of cannabis use as well as positive THC urine drug screen results were associated with greater physical IPV victimization, and greater quantity and frequency of cannabis were associated with greater IPV psychological victimization and perpetration, and physical IPV victimization.

Conclusion and Scientific Significance

Findings emphasize the unique and important role that cannabis plays in the occurrence of IPV among intact couples. Findings also underscore the feasibility and utility of integrating confirmatory biological samples into future studies on this topic in order to advance the science in this area. (Am J Addict 2020;00:00–00)
Alcohol Use Disorder Among Adults Recovered From Substance Use Disorders
Authors: Rhee Taeho Greg , Rosenheck Robert A.
Published: March 2020

Background and Objectives

Alcohol use is often overlooked and underestimated among patients recovered from substance dependence. The prevalence and correlates of alcohol use disorder (AUD) among adults recovered from substance use disorders (SUDs) are estimated in this study.

Methods

A nationally representative cross‐sectional analysis of the National Epidemiological Survey on Alcohol and Related Conditions Wave‐III was used in this study. Survey respondents, aged 18 or older, who recovered from SUDs, based on Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM‐5) criteria (n = 2061 unweighted), were included. A total of three comparison groups were identified using DSM‐5 criteria (1) current AUD, (2) former AUD, and (3) never had AUD. The prevalence of these groups was estimated; medical and psychiatric comorbidities and health‐related quality of life were compared; and factors associated with having a current AUD when compared with those with former AUD and those who never had AUD were examined, controlling for other covariates.

Results

About 5.7% of US adults, nationally representative of 14.2 million, have been reported to have recovered from past SUDs. Of these, 28.9% met criteria for current AUD and 48.4% had former AUD. When compared with those who never had AUD, factors associated with having a current AUD included the following: living in urban areas (P = .019), having a bipolar 1 disorder (P < .001), and a history of lifetime incarceration (P = .004).

Discussion and Conclusion

Nearly one‐third of adults recovered from SUDs had current AUD, and several behavioral factors were associated with having a current AUD when compared with those who never had AUD.

Scientific Significance

Our study highlights the substantial risk of AUD in adults who have successfully recovered from SUDs. (Am J Addict 2020;00:00–00)
Frequency of food allergy in school‐aged children in eight European countries—The EuroPrevall‐iFAAM birth cohort
Authors: Grabenhenrich Linus , Trendelenburg Valérie , Bellach Johanna , Yürek Songül , Reich Andreas , Fiandor Ana , Rivero Daniela , Sigurdardottir Sigurveig , Clausen Michael , Papadopoulos Nikolaos G. , Xepapadaki Paraskevi , Sprikkelman Aline B. , Dontje Bianca , Roberts Graham , Grimshaw Kate , Kowalski Marek L. , Kurowski Marcin , Dubakiene Ruta , Rudzeviciene Odilija , Fernández‐Rivas Montserrat , Couch Philip , Versteeg Serge A. , van Ree Ronald , Mills Clare , Keil Thomas , Beyer Kirsten
Published: March 2020

Background

The prevalence of food allergy (FA) among European school children is poorly defined. Estimates have commonly been based on parent‐reported symptoms. We aimed to estimate the frequency of FA and sensitization against food allergens in primary school children in eight European countries.

Methods

A follow‐up assessment at age 6‐10 years of a multicentre European birth cohort based was undertaken using an online parental questionnaire, clinical visits including structured interviews and skin prick tests (SPT). Children with suspected FA were scheduled for double‐blind, placebo‐controlled oral food challenges (DBPCFC).

Results

A total of 6105 children participated in this school‐age follow‐up (57.8% of 10 563 recruited at birth). For 982 of 6069 children (16.2%), parents reported adverse reactions after food consumption in the online questionnaire. Of 2288 children with parental face‐to‐face interviews and/or skin prick testing, 238 (10.4%) were eligible for a DBPCFC. Sixty‐three foods were challenge‐tested in 46 children. Twenty food challenges were positive in 17 children, including seven to hazelnut and three to peanut. Another seventy‐one children were estimated to suffer FA among those who were eligible but refused DBPCFC. This yielded prevalence estimates for FA in school age between 1.4% (88 related to all 6105 participants of this follow‐up) and 3.8% (88 related to 2289 with completed eligibility assessment).

Interpretation

In primary school children in eight European countries, the prevalence of FA was lower than expected even though parents of this cohort have become especially aware of allergic reactions to food. There was moderate variation between centres hampering valid regional comparisons.
Quality of life of adults born very preterm or very low birth weight: A systematic review
Authors: van der Pal Sylvia , Steinhof Malte , Grevinga Manon , Wolke Dieter , Verrips Gijsbert (Erik)
Published: March 2020

Aim

To establish differences in health‐related quality of life (HRQoL) in adults born term and those born very preterm (VPT) and/or with a very low birth weight (VLBW).

Methods

Our systematic review is preregistered under PROSPERO‐ID CRD42018084005. Studies were eligible for inclusion if their authors had stated the HRQoL of adults (18 years or older) born VPT (<32 weeks of gestation) or VLBW (<1500 g of birth weight) had been measured, if written in English, and if they reported a comparison with a control group or valid norms. We searched Pubmed, Scopus, Psycinfo, Web of Science, Embase and contacted experts in this field. Non‐response and other bias‐related problems were evaluated.

Results

We included 18 studies of 15 unique cohorts from 11 countries. In 11 studies, no differences in HRQoL between VPT or VLBW and term‐born adults were found; four studies found lower HRQoL in VPT/VLB adults; and evidence from three studies was inconclusive. Disability, sex and age were associated with HRQoL.

Conclusion

There is no conclusive evidence that HRQoL differs between term‐born adults and those born VPT or with a VLBW. The comparability of studies was restricted by differences between HRQoL measurements, age ranges at assessment and definition of disability.
Children with vaccination granulomas and aluminum contact allergy: Evaluation of predispositions, avoidance behavior, and quality of life
Authors: Hoffmann Stine S. , Thyssen Jacob P. , Elberling Jesper , Hansen Kirsten S. , Johansen Jeanne D.
Published: March 2020

Background

Aluminum contact allergy is mostly seen in children with vaccination granulomas, following immunization with aluminum‐adsorbed childhood vaccines.

Objectives

To characterize a cohort of children with vaccination granulomas and aluminum allergy concerning early life conditions, exacerbating factors, avoidance behavior, treatments, and potential impact on quality of life.

Methods

A questionnaire study was conducted among 177 children aged 0 to 15 years with vaccination granulomas and aluminum allergy, and a reference group of 61 children aged 3 to 14 years with various types of dermatitis undergoing patch testing.

Results

All children in the granuloma group were reportedly affected by itch. Infection exacerbated the itch in 59%. Other worsening factors were eating tin‐foiled/canned food (31%) and use of aluminum‐containing sunscreen (46%). Many parents took precautions to avoid aluminum exposure. Children with granulomas were more likely to be nonadherent to the National Vaccination Program than the reference group (27% vs 2%, P < .001). Parents in the granuloma group reported a decreased life quality for both parents and children compared with the reference group.

Conclusions

Itching vaccination granulomas and aluminum allergy have a considerable negative impact on affected children and their families, causing avoidance behavior, reduced adherence to vaccination programs, and a negative effect on the overall life quality.
Internal drainage by cutting the nasobiliary tube after endoscopic ultrasound‐guided hepaticogastrostomy
Authors: Miwa Haruo , Sugimori Kazuya , Maeda Shin
Published: March 2020

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Male‐biased Demand Shocks and Women's Labour Force Participation: Evidence from Large Oil Field Discoveries
Authors: Maurer Stephan E. , Potlogea Andrei V.
Published: March 2020

Do male‐biased labour demand shocks affect women's labour market outcomes? To study this question, we examine large oil field discoveries in the southern USA from 1900 to 1940. We find that oil wealth has an overall positive effect on female labour force participation that is driven by single women. While oil discoveries increase demand for male labour and raise male wages, they do not drive women out of the tradable goods sector or the labour force. Our findings suggest that the absence of any crowding out effects of oil wealth can be explained by compensating forces such as demand effects within the tradable sector, or by income effects that lead to growth in the non‐tradable sector.
GENDER AND THE CONSULTING ACADEMIC ECONOMIST
Authors: Del Rossi Alison F. , Hersch Joni
Published: March 2020

We surveyed academic economists on their experiences and perceptions of legal consulting. Nearly two‐thirds have consulting experience and 40% have consulted within the last 5 years. Base hourly rates average $244, with a median of $200. Women are less likely than men to have served as consultants and charge lower rates than comparable men, but there are few differences by gender in willingness to consult. Women report substantially more negative bias and are less likely to consult in complex cases or to have a high profile role in litigation. (JEL J44, J71, K41)
Data envelopment analysis and robust optimization: A review
Authors: Peykani Pejman , Mohammadi Emran , Saen Reza Farzipoor , Sadjadi Seyed Jafar , Rostamy‐Malkhalifeh Mohsen
Published: March 2020

This paper reviews the milestone approaches for handling uncertainty in data envelopment analysis (DEA). This paper presents the detailed classifications of robust data envelopment analysis (RDEA). RDEA is appropriate for measuring the efficiencies of decision‐making units in the presence of the data and distributional uncertainties. This paper reviews scenario‐based and uncertainty set of DEA models. It covers 73 studies from 2008 to 2019. The paper concludes with suggestions about the guidelines for future researches in the field of RDEA.
Marital Conflict in the Context of Novel Stress: Associations with Physiological Stress Functioning
Authors: Seiter Natasha S. , Lucas‐Thompson Rachel G.
Published: March 2020

Objectives

The goal of this study was to investigate associations of the positivity and negativity of couple communication behaviors during a novel stressor, representative of dyadic coping, with diurnal cortisol patterns, an indication of stress physiological functioning.

Background

Previous research suggests that less positive and more negative couple interactions about reoccurring relationship issues are stressful and, as a result, are associated with physiological stress dysregulation. Past research has also indicated that behaviors during novel, as opposed to reoccurring, stressors are uniquely predictive of couple outcomes because behaviors during novel stressors are indicative of patterns of dyadic coping. However, there is not yet evidence linking couple behaviors in response to novel stressors to physiological stress functioning.

Methods

Sixty‐one (N = 122 individuals) heterosexual couples completed a novel stress task, and recordings of their interactions were coded for negative and positive communication behaviors. Couples provided saliva samples at home for 2 days, which were assayed for diurnal cortisol concentrations.

Results

Results of linear regression and structural equation modeling analyses suggested that women's greater positive, in relation to negative, communication behavior during the novel stressor was associated with women's greater cortisol awakening levels and cortisol awakening responses. Men's greater positive behavior was associated with men's and women's greater cortisol awakening levels, that is, signs indicating healthy physiological functioning.

Conclusion

Couples' dyadic coping has implications for the functioning of stress systems.

Implications

Specifically, couples' communication quality during novel stressors may protect from physiological stress dysregulation; the manner in which couples treat each other when facing novel stress can get “under the skin.”
Exploring Home Management Houses: Part II Two Case Studies: The University of Georgia and Texas Tech University
Authors: Nickols Sharon Y. , Allison Barbara N.
Published: March 2020

Home management courses, and the houses where those course principles and practices were applied, played an historical role in the home economics curriculum in the United States from the 1920s to the 1980s. The residence course was taught in a variety of settings. However, the course was taught most often in houses located on campus. Using multiple research methods, this study explored home management courses and residences at the University of Georgia and Texas Tech University. Part I which was published in the March issue of the Family & Consumer Sciences Research Journal provided a general historical overview and a case study of the home management houses at Kansas State University. Eventually, the home management houses were repurposed to meet changing academic, research, and public service needs over their decades‐long history. Opportunities for future research are explored.
Depression in diabetic foot ulcer: Associated factors and the impact of perceived social support and anxiety on depression
Authors: Polikandrioti Maria , Vasilopoulos Georgios , Koutelekos Ioannis , Panoutsopoulos Georgios , Gerogianni Georgia , Alikari Victoria , Dousis Evaggelos , Zartaloudi Afroditi
Published: March 2020

Diabetic foot ulcer (DFU) exerts a heavy physical and emotional burden on patients with diabetes mellitus. The purpose of the present study was to explore the impact of anxiety and perceived social support on depression of DFU patients well as patients' characteristics associated with depression. The sample of the study consisted of 180 DFU patients. Data collected by the completion of “Self‐rating Depression/Anxiety Scale‐ Zung” (SDS/SAS) and the Multidimensional Scale of Perceived Social Support (MSPSS). Patients had moderate levels of anxiety and depression (median: 36, 42, respectively) and high levels of perceived social support from their significant ones, their family and friends (median: 24, 24, 17, respectively). After multiple regression factors that were found to have an impact on depression after taking into account all other factors, were patient's age of above 70 years, patient's anxiety and the social support they received from their significant ones. More specifically, patients aged above 70 years had 9.51 points higher depression than patients aged <50 years of age (β = 9.51, 95% CI: [0.76, 18.25], P = .034). Moreover, one point increase in patient's anxiety score indicated an increase of 0.71 points in patient's depression (β = 0.71, 95% CI: [0.43, 1.00], P = .001). On the contrary, one point increase in patient's social support from their significant ones indicated a decrease of 1.52 points in patient's depression (β = −1.52, 95% CI: [−0.25, −2.79], P = .020). Clinically, a better understanding of factors having an impact on depression on DFU may provide an essential in planning cost effective interventions.
Researching children: some methodological and ethical considerations
Authors: Coyne Imelda T.
Published: March 2020

This paper examines some of the methodological issues and ethical considerations in researching children.

Collecting data from children raises issues of informed consent, establishing rapport, and privacy and confidentiality.

Children's consent to research remains a contentious issue that requires further deliberations.

Researchers need to be flexible in their research with children and be cognisant of the strategies that can be used to enhance the quality of responses from children.
Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro‐myelinating genes
Authors: Huff Tyler C. , Sant David W. , Camarena Vladimir , Van Booven Derek , Andrade Nadja S. , Mustafi Sushmita , Monje Paula V. , Wang Gaofeng
Published: March 2020

Ascorbic acid (vitamin C) is critical for Schwann cells to myelinate peripheral nerve axons during development and remyelination after injury. However, its exact mechanism remains elusive. Vitamin C is a dietary nutrient that was recently discovered to promote active DNA demethylation. Schwann cell myelination is characterized by global DNA demethylation in vivo and may therefore be regulated by vitamin C. We found that vitamin C induces a massive transcriptomic shift (n = 3,848 genes) in primary cultured Schwann cells while simultaneously producing a global increase in genomic 5‐hydroxymethylcytosine (5hmC), a DNA demethylation intermediate which regulates transcription. Vitamin C up‐regulates 10 pro‐myelinating genes which exhibit elevated 5hmC content in both the promoter and gene body regions of these loci following treatment. Using a mouse model of human vitamin C metabolism, we found that maternal dietary vitamin C deficiency causes peripheral nerve hypomyelination throughout early development in resulting offspring. Additionally, dietary vitamin C intake regulates the expression of myelin‐related proteins such as periaxin (PRX) and myelin basic protein (MBP) during development and remyelination after injury in mice. Taken together, these results suggest that vitamin C cooperatively promotes myelination through 1) increased DNA demethylation and transcription of pro‐myelinating genes, and 2) its known role in stabilizing collagen helices to form the basal lamina that is necessary for myelination.

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Exposure of female mice to perfluorooctanoic acid suppresses hypothalamic kisspeptin‐reproductive endocrine system through enhanced hepatic fibroblast growth factor 21 synthesis, leading to ovulation failure and prolonged dioestrus
Authors: Zhang Yajie , Cao Xinyuan , Chen Lin , Qin Yaoyao , Xu Ye , Tian Ying , Chen Ling
Published: March 2020

Perfluorooctanoic acid (PFOA) is widely used in household applications. High‐dose exposure to PFOA has been associated with increased risks of infertility and premature ovarian insufficiency in woman. PFOA can alter hepatic gene expression by activating peroxisome proliferator‐activated receptor α (PPARα). The present study investigated whether exposure to PFOA via PPARα activation alters the synthesis of hepatic fibroblast growth factor 21 (FGF21) to disturb female neuroendocrine and reproductive function. In the present study, we show that the oral administration of PFOA (2 or 5 mg kg‐1) in adult female mice (PFOA mice) caused prolonged dioestrous, a reduction in the number of corpora lutea and decreased levels of hypothalamic gonadotrophin‐releasing hormone, serum progesterone and luteinising hormone (LH). Exposure to PFOA decreased the expression of vasopressin in the suprachiasmatic nucleus (SCN) and kisspeptin in the anteroventral periventricular nucleus (AVPV) with deficits in preovulation or oestrogen‐induced LH surge. PFOA via activation of PPARα increased dose‐dependently hepatic FGF21 expression, leading to elevated serum and hypothalamic FGF21 concentrations. Treatment of PFOA mice with the PPARα antagonist GW6471 or the FGF21 inhibitor PD173074 rescued SCN vasopressin and AVPV‐kisspeptin expression. Either administration of GW6471 and PD173074 or treatment with vasopressin and the G protein coupled receptor 54 agonist kisspeptin‐10 in PFOA‐mice was able to recover the regular oestrous cycle, ovulation ability, LH surge production and reproductive hormone levels. The present study provides in vivo evidence that exposure to PFOA (≥2 mg kg‐1) in mice causes down‐regulation of the kisspeptin‐reproductive endocrine system by enhancing PPARα‐mediated hepatic FGF21 expression. The liver‐brain reproductive endocrine disorder caused by PFOA exposure may lead to prolonged dioestrous and ovulation failure.
The Relationship between Written District Policies and School Practices among High‐Need Districts in New York State
Authors: Boehm Rebecca , Schwartz Marlene B. , Lowenfels Ann , Brissette Ian , Pattison Mary Jo , Ren Jia
Published: March 2020

BACKGROUND

This study tested the hypothesis that written district wellness policies are associated with higher rates of implementation of nutrition and physical activity practices.

METHODS

Written wellness policies and building level practices were assessed for schools (N = 295) within high‐need districts (N = 70) in New York State. The relationship between policies and practices was measured using multi‐level mixed‐effects logistic regressions.

RESULTS

Overall, stronger written district policies significantly increase the likelihood of practice implementation in schools. This relationship is strongest for physical education and physical activity items, followed by nutrition standards for competitive foods in middle and high schools. Most elementary schools implemented nutrition practices with or without a policy and there were differences in implementation rates between elementary and middle/high schools. When examined separately, policies were for the most part not significantly associated with implementation of corresponding practices.

CONCLUSIONS

Strong and comprehensive written policies are associated with higher rates of practice implementation overall, but the consistency of this relationship varies by policy‐practice domain. The newer policy topics areas of school wellness promotion and marketing were less frequently included in written policies. Future research should examine whether districts that strengthen their written policies achieve greater implementation over
time.