bluuebunny/crossref_metadata_2025 huggingface dataset:
Metode Stabilisasi Semen Terhadap Peningkatan Nilai CBR Tanah Dasar Jalan Lingkungan
Authors: Firdaus Muhammad , Suhaimi Muhammad , Fathurrozie Fathurrozie
Published: June 2021

Dalam makalah ini mendiskusikan  mengenai  pengembangan  fasilitas infrastruktur  umum di Komplek  Bumi Mas Lestari  Perdagangan  Banjarmasin  yaitu Pembangunan  Jalan lingkungan  yang secara khusus  meninjau  bagian tanah dasar dan ketebalan  timbunan  sirtu. Perhitungan  daya dukung  tanah dasar mengacu kepada input nilai CBR metode SNI yaitu index dan engineering  properties,  uji kepadatan tanah standar proctor di laboratorium dan uji CBR Laboratorium. Studi penelitian terhadap tanah dasar yang dibandingkan adalah tanpa dan dengan penggunaan penambahan semen 9% terhadap tanah asli lanau lunak berlempung  plastisitas  rendah,  hasil  yang  dapat  mewakili  untuk  perbandingan  nilai  kelayakan  subgrade adalah pemenuhan terhadap ketentuan nilai CBR subgrade pada Spesifikasi Umum Bina Marga sebesar minimum 6% pada pelaksanaan timbunan jalan, karena antara nilai CBR tanah dasar asli yang dihasilkan 4% dan setelah distabilisasi menggunakan semen menghasilkan  peningkatan 9,8%, tanah dasar telah memenuhi persyaratan   dan  dapat  digunakan   menjadi  bagian  dari  konstruksi   perkerasan   jalan  diatasnya  sebagai penopang.

Abstract

This  paper  discuss  infrastucture  development  of  road  transportation  in  Bumi  Mas  Lestari Housing   Compex   Construction   mainly   Road   access   facility   construction   mainly   for   subgrade   and embankment of  thickness materials. The calculation of theoretical bearing   capacity of subgrade based on Standar Nasional Indonesia (SNI), including Proctor Standard and CBR test laboratory.research  focus on cement mixing between natural condition of subgrade using 9% cement ratio in silty clayey low plasticity type of soil sample. Conduct Bina Marga Specification of Road Construction,  minimum CBR Design is 6% was allowed with 9,8% CBR Design after mixing cement as stabilitation of 4% CBR design before.
Pengaruh Penambahan Plastik LDPE Terhadap Hasil Marshall untuk HRS-WC
Authors: Hawinuti Riska , Surat Surat , Gazalie Rifanie
Published: June 2021

Plastik sebagai hasil sampingan dari aktivitas masyarakat, menjadi penyumbang terbesar sampah di Indonesia, sehingga diperlukan penanganan khusus agar permasalahan plastik tersebut dapat terselesaikan. Salah satunya adalah dengan memanfaatkan plastik tersebut sebagai bahan tambahan campuran beraspal HRS-WC sehingga diharapkan selain berkurangnya jumlah sampah, jumlah penggunaan aspal minyak pun dapat ditekan. Tujuan penelitian ini adalah mengetahui pengaruh penambahan plastik LDPE (Low Density Poly Ethylene) terhadap karakteristik campuran beraspal HRS-WC, mengetahui perbandingan nilai karakteristik marshall antara campuran HRS-WC dengan dan tanpa tambahan plastik LDPE, menentukan kadar aspal optimum dan kadar campuran plastik LDPE optimum pada campuran HRS-WC.

Pengujian yang dilakukan di Laboratorium Struktur dan Bahan Poliban, antara lain pengujian agregat, pengujian aspal dan  pengujian marshall. Benda uji yang dibuat berupa benda uji tanpa tambahan plastik dan dengan tambahan plastik sebanyak masing-masing 15 buah.

 Dari hasil pengujian, campuran aspal tanpa Plastik LDPE diperoleh nilai stabilitas 1.490 kg, flow 4,20 mm, VMA 110% dan Marshall Quotient 380 kg/ mm sedangkan pada campuran dengan plastik LDPE, nilai stabilitas sebesar 1.900 kg, flow 4,20 mm, nilai VMA105% dan nilai Marshall Quotient 610 kg /mm. Dengan nilai KAO sebesar 6,50% dan kadar plastik sebesar 5,0%.
Analisis Ketersediaan Dan Kebutuhan Air Irigasi Pada Petak Sawah Di Daerah Irigasi Rawa Kecamatan Mandastana
Authors: Iriansyah Andri , Hayati Fitriani , Fakhrurrazi Fakhrurrazi
Published: June 2021

Kabupaten Barito Kuala adalah salah satu pemerintah kabupaten yang berbatasan dengan provinsi Kalimantan Tengah dan Kalimantan Selatan, Indonesia. Dalam musim hujan pada waktu pasang air Sungai Kapuas, Sungai Barito dan air kiriman dari Kabupaten Banjar yang berbatasan langsung dengan Kecamatan Mandastana dapat membanjiri sebagian besar wilayah ini dan mengakibatkan permukaan tanah tergenang terus menerus. Masalah yang dialami oleh persawahaan di Kecamatan Mandastana adalah masalah yang mempengaruhi tata kelola air terkait saluran irigasi yang ada di pertanian itu sendiri mengalami pasang surut air, yang bergerak naik turun yang disebabkan oleh pasang air pada Sungai Barito dan Sungai Kapuas, dimana pada saat pasang area persawahan mengalami kelebihan air. Metode perhitungan yang digunakan dalam penelitian ini adalah metode mock untuk perhitungan debit andalan dan neraca air dan metode penman dan standar KP-01 untuk perhitungan kebutuhan air. Berdasarkan analisis neraca air  (ketersediaan air dari curah hujan dikurang kebutuhan air disawah kondisi eksisting) didapat hasil 3,017 m3/detik, sehingga pada petak sawah terjadi kelebihan air, jadi apabila ingin dilakukan perluasan lahan persawahan ketersediaan air masih mencukupi untuk mengairi air di sawah.

Abstract

Barito Kuala Regency is one of the district governments that borders the provinces of Central Kalimantan and South Kalimantan, Indonesia. During the rainy season at the time of the tide of the Kapuas River, the Barito River and consignment water from Banjar Regency, which is directly adjacent to Mandastana District, can overwhelm most of this area and result in continuous inundation of the land surface. The problem experienced by the field in Mandastana Subdistrict is a problem that affects water management related to irrigation channels in agriculture itself which experiences tidal water, which moves up and down caused by tides on the Barito River and Kapuas River, where at the time of tide the area rice fields experience excess water. The calculation method used in this study is the mock method for calculating the mainstay discharge and water balance and penman method and the KP-01 standard for calculating water requirements. Based on the analysis of water balance (availability of water from rainfall minus water requirements under existing conditions) obtained results of 3.017 m3 / sec, so that the paddy fields occur excess water, so if you want to expand rice fields the availability of water is still sufficient to irrigate water in the fields.
Sistem Pendukung Keputusan Rekomendasi Pekerjaan Bagi Fresh Graduate Dengan Penggabungan SAW Dan TOPSIS
Authors: Putra Rahardhiyan Wahyu , Rosiani Ulla Delfana
Published: June 2021

Sistem Pendukung Keputusan merupakan suatu system yang mendukung manusia untuk menentukan sesuatu berdasarkan perhitungan matematika. Sistem Pendukung Keputusan akan dibuat oleh peneliti sebagai alat yang nantinya digunakan untuk membantu para Fresh Graduate untuk memilih pekerjaan sesuai dengan minatnya. Objek penelitian yang akan digunakan yaitu para lulusan Jurusan Teknologi Informasi pada Politeknik Negeri Malang. Penggunaan metode untuk sistem ini menggabungkan metode SAW dan Topsis. Penelitian ini menggunakan lima kriteria yaitu IPK, akreditasi, usia, Pendidikan terakhir dan kemampuan berbahasa inggris. Sistem akan menilai dari setiap input user pada tiap kriteria lalu dilakukan perhitungan dengan metode SAW dan Topsis. Diharapkan adanya sistem pendukung keputusan ini membantu para Fresh Graduate terutama lulusan jurusan teknologi informasi pada politeknik negeri malang menemukan pekerjaan yang sesuai
İstemli Egzersizin Sıçanlarda Fruktozdan Zengin Beslenmeyle Uyarılan Böbrek Fonksiyon Bozukluğu ve Oksidan Durumu Düzeltici Etkisi
Authors: KAYA Oktay , ERÇETİN Deniz , AYDIN Muhammed Ali , SAPMAZ Melike
Published: June 2021

Fruktoz tüketimindeki artışın oksidatif stresi artırarak böbrek fonksiyonlarını olumsuz etkilediği bilinmektedir. Egzersizin böbrek için koruyucu etkileri olduğu gösterilmiş olmasına karşın fruktozdan zengin beslenmeye bağlı değişimlerde istemli koşu egzersizinin etkileri bilinmemektedir. Çalışmamızda yüksek fruktozla beslenmenin böbrek fonksiyonu ve histolojisi üzerine meydana getirdiği olası etkiler ve oksidatif hasarda istemli fiziksel aktivitenin rolünü araştırdık. Deneyde kullanılan 21 adet erkek Sprague Dawley sıçan 3 gruba ayrıldı. Sekiz hafta süren deney boyunca Sedanter+su (kontrol) grubu içme suyu alırken sedanter+fruktozlu su (F) ve aktivite+fruktozlu su (A+F) grupları %20 fruktoz içeren içme suyu aldılar. A+F grubu 8 hafta boyunca dönen tekerlek bulunan kafes yardımıyla istemli fiziksel aktivite yaptı. Deney sonunda alınan kan örneklerinde üre ve kreatinin seviyeleri, böbrek dokularında malondialdehit ve glutatyon düzeyleri incelendi. Ayrıca böbrek dokusunun histopatolojik incelemesi yapıldı. Böbrek fonksiyonlarının göstergesi olan serum kreatinin seviyesi F grubunda kontrol grubuna göre yüksek bulundu (p=0,012). Malondialdehit (MDA) seviyesi F grubunda kontrol grubuna göre yüksek iken A+F grubunda kontrol grubuyla benzerdi (sırasıyla p=0,024 ve p>0,99). Glutatyon (GSH) seviyesi F ve A+F gruplarında kontrol grubuna göre yüksekti (sırasıyla p=0,015 ve p=0,001). GSH seviyesi A+F grubunda F grubuna göre anlamlı düzeyde yüksekti (p=0,014). Kontrol grubuna kıyasla F grubunun böbrek kesitlerinde glomerüler çap, glomeruloskleroz oranı ve kollajen yoğunluğunda artış görüldü. A+F grubunda kontrol grubuna benzer histolojik görünüm saptandı. Bu çalışma ile yüksek fruktozla beslenmeye bağlı böbrek yapısı ve fonksiyonlarında meydana gelen olumsuz etkilerin ve oksidatif hasarın istemli fiziksel aktivite ile önlenebileceği ortaya konmuştur.
Üzerine Televizyon Düşmesi Sonucu Meydana Gelen Çocuk Ölümlerinin Retrospektif Değerlendirilmesi
Authors: GÖK Ertuğrul , FEDAKAR Recep , SİVRİ Süleyman
Published: June 2021

Televizyon düşmesi, çocuklarda sıklıkla künt kafa travmasına bağlı önemli morbidite ve mortalite nedenidir. Televizyon düşmesi nedeniyle ölen olguların detaylı incelenmesi alınacak tedbirler için yol gösterici olacaktır. Bu çalışmada Adli Tıp Kurumu Diyarbakır Grup Başkanlığı tarafından 2005-2014 yılları arasında Diyarbakır’da ölü muayeneleri veya otopsileri yapılmış olan 9174 olgunun ölü muayene veya otopsi raporları incelendi. İncelenen olgulardan üzerine televizyon düşmesi nedeniyle ölmüş olduğu kesin olan çocuk yaş grubundaki 24 olgu çalışmaya alındı. Olguların tamamının (n=24) künt kafa travmasına bağlı öldükleri, hepsinin yaş grubunun 1-4 yaş aralığında olduğu, olguların 13 (%54,2) tanesinin kız cinsiyette olduğu ve en çok olguya yaz mevsiminde (%45,8) rastlandığı saptandı. Televizyon düşmesine bağlı ölümlerin tamamının kaza kaynaklı önlenebilir halk sağlığı sorunu olduğu saptandı.
Ventriküloperitoneal Şant Kateter Distal Ucunun Torasik Migrasyonu: Olgu Sunumu
Authors: KASAB Reyhan , ESER OCAK Pınar , TUNÇBİLEKLİ Yağmur , BAYRAM Sami , TAŞKAPILIOĞLU M Özgür
Published: June 2021

Hidrosefali, beyin omurilik sıvısında artış ile seyreden, serebral ventriküllerde genişlemeye ve serebral kortekste incelmeye neden olan artmış intrakraniyal basınç ile karakterize yaygın bir nöroşirurjikal hastalıktır. Hidrosefalinin yönetiminde en sık kullanılan tedavi yöntemi ventriküloperitoneal şanttır. Şant işlemi sonrası daha çok mekanik obstrüksiyonlar ve enfeksiyonlar görülmektedir. Torasik migrasyon oldukça nadir görülür fakat görüldüğü zaman ivedilikle müdahale edilmesi gereken bir tablodur.
EPTCast – Une proposition de diffusion scientifique dans l’enseignement professionnel et technologique brésilien
Authors: Ramos Rogério Luiz da Silva , Fecury Amanda Alves , Oliveira Euzébio de , Dendasck Carla Viana , Dias Claudio Alberto Gellis de Mattos
Published: June 2021

Ce travail consiste en un rapport d’expérience concernant le développement d’EPTCast, produit éducatif développé tout au long du master professionnel en enseignement professionnel et technologique en réseau national (ProfEPT). Basé sur le manque de diffusion scientifique spécifiquement axée sur le domaine de l’enseignement professionnel et technologique brésilien (EPT), ce travail vise à promouvoir des initiatives en ce sens, contribuant ainsi à la vulgarisation de la scientificité de ce domaine. À cette fin, ici, le processus de construction et de distribution via podcast d’un contenu audio visant à la diffusion scientifique de l’EPT brésilien est dépeint. En ce sens, la question de l’écart est d’abord abordée et, par conséquent, la nécessité de populariser la scientificité de ce domaine. Dans un second temps, la conception et les technologies utilisées dans la construction de l’objet EPTCast sont présentées. Populariser la scientificité de l’éducation professionnelle et technologique brésilienne est ce qui est prévu à travers ce travail – qui ne sera pas le seul. Par ce qui a été exposé dans les sections précédentes, il est donc destiné à contribuer à la vulgarisation d’une scientificité qui n’est parfois pas encore comprise comme telle.
ncentive Effects Analysis on Primary and Secondary Teacher Incentive Policies in China
Authors: Longlong Hou , Ping Zhao , Oladele Ogunniran Moses
Published: June 2021

In recent years, many policies issued by central and local governments for primary and secondary school teachers in China are closely related to the incentive problems in their work. Based on the policy texts and empirical studies about teachers’ incentives, this paper discusses the incentive effects of teacher incentive policies. The outlines of this study are as follows: 1.Teacher incentive policies; 2. The incentive methods of teacher incentive policies; 3. Incentive effects of teacher incentive policies; 4. Teachers’ workloads and the effects of teacher incentive policies; and 5. Suggestions on teacher incentive policies.
Totalidad y complejidad. Notas sobre la concepción del pensamiento complejo.
Authors:   Universidad de Guadalajara, Hurtado Lopez Jorge Arturo
Published: June 2021

Due to the interest that the ideas of the authors of the theory of complex thought arouse for the development of scientific research, especially that dedicated to the sciences of society, we consider that the examination of some of their concepts can contribute to the clarification of their approaches ; It is because of this that we propose in this essay to analyze the concepts of complexity and totality, from the perspective of Edgar Morin, as they appear mainly exposed in his text Introduction to complex thinking (Morin, 2008 [1990]). The theses presented in this essay are an initial approach to the work of this thinker.
Criterios de planeación para instrumentar políticas y estrategias en un proceso de reingeniería empresarial.
Authors:   Universidad de Guadalajara, Morán Martínez Francisco , Uribe Ramos Alejandra ,   Universidad de Guadalajara
Published: June 2021

The company is an entity that sustains in organizing and developing economic activities of a productive branch or sector in an economic system. In the organization of the company as a corporation, there are circumstances that require decision-making to resolve situations that require obtaining financial resources to carry out a technological renovation or a total reengineering of the company. For this, it is essential to clarify what the criteria of planning that a company must take into account if it needs to carry out an investment project, either for a technological reconversion or a total reengineering process of the productive entity.This document describes how the policies and strategies regarding economic policy established in the National Development Plan, as well as the sectoral and regional plans, to determine the context in which the activities of the economic entity are developed. The process of the different stages of project evaluation for reengineering is emphasized, which contributes to a more efficient decision-making of the best investment alternative.
La imposibilidad y el desencuentro: el no-diálogo con Dios en dos poemas religiosos de Blas de Otero y Alfredo R. Placencia.
Authors:   Universidad Marista de Guadalajara (MÉXICO), Casillas Padilla Enrique
Published: June 2021

In this article, is made an approximation from the Stylistics and the Comparative Literature of religious poems of the Mexican poet Alfredo R. Placencia (1875-1930) and the Spanish poet Blas de Otero (1916-1979). Through analysis, it is identified in his works the configuration of the human and the divine being and the way they enter into dialogue. The poems studied “La caña quebrada” (1924) and “Muerte en el mar” (1951) have as their common characteristic their apostrophic character, its means, that the verses are addressed to an interlocutor who, in all cases, will be an image divine, who by silence or absence, does not respond to the questioning of the poetic subject. The interpretation of the poems through Comparative Literature, after the stylistic analysis, allows to observe common features with a type of religious poetry characteristic of the Hispanic environment, as well as more universal aspects of religious poetic production in the first-half 20th century.
Esquizoanálisis y necropoder: la representación del (narco) capitalismo y la violencia en la narconarrativa mexicana reciente.
Authors:   Departamento de Humanidades. Universidad Iberoamericana-Puebla (MÉXICO), Castillo-Carrillo Gerardo
Published: June 2021

In this writing, under the precepts of schizoanalysis (Deleuze & Guattari) and necropower (Mbembe), it will be reviewed that the drug trafficking novel focuses on reproducing two discursive constants exposed in a customary way by official institutions (government, media, entertainment industry, etc.): (narco) capitalism and violence. As a central purpose, I will analyze in what way in this narrative the systematic terrorism exercised by the drug cartels through their economic power, who, acting as large transnational corporations, can corrupt all social strata, thus establishing themselves as the supreme socius; thus evidencing that these criminal organizations fragment, control and transgress public space.
Sueño, poesía y realidad latinoamericana en Me alquilo para soñar, de Gabriel García Márquez.
Authors:   Universidad Nacional de Seúl (COREA DEL SUR), Park Seohyeok
Published: June 2021

The present article reviews the configuration of dream as the fantastic and poetry as another dimension of reality, in the short story “Me alquilo para soñar” by García Márquez. Three dimensions are highlighted in which three main characters are embodied: the life-dream, the life-poetry and the life-narrative, which share creation as a common foundation. The main objective is to demonstrate that the mechanism of creation is the same, the imaginative recreation, and to analyze the strategy of verisimilitude conjoining the perspective of the experience of the reader, in order to scrutinize the reality of Latin Americans who are presented to the reader in this short story.
Enfrentar las estructuras de opresión: sumisión, resiliencia y resistencia en Los ojos más azules y El color púrpura.
Authors:   Facultad de Lenguas de la Universidad de la Habana (CUBA), Ayala Rodríguez Ida María , Gavilla Lundeg Cristina Amalia ,   Human Internacional School of Mongolia (MONGOLIA)
Published: June 2021

This paper focuses on and compares several aspects of the novels The Bluest Eye by Toni Morrison and The Color Purple by Alice Walker. This analysis is preceded by a brief historical background of the times when the action of the novels take place, necessary to understand the history of racial discrimination and the prejudices that sustain this discrimination to our days. The discursion shows the main female characters reacting towards the different forms of oppression and to the systematic suppression of the necessary conditions for the normal development of their self- esteem as human beings. The self-esteem of some of them is so low that they cannot recover; others rise and are able to recover their lost self-esteem. We conclude that the lives of the characters in The Bluest Eye were influenced by racial, social and patriarchal prejudices, prevented from material advancement, and in some cases, how their expectations for a better life were crushed in the end leading them into catastrophic events. In The Color Purple, characters are able to overcome the effects of oppression with the help of the solidarity of women and their personalities can survive almost intact. Thus they show resilience in the face of adversity.
La percepción del cuerpo y la tecnología en el cuento de ciencia ficción La máquina de respirar de Juan Pablo Goñi Capurro.
Authors:   Departamento de Letras. Universidad de Guadalajara (MÉXICO), García Serrano Carmina Alejandra
Published: June 2021

This article analyzes the science fiction story called La máquina de respirar by the author Juan Pablo Goñi Capurro. The purpose of the article is to determine the way in which the new technology is presented compared to the old technology, to determine what its impact is based on the proposal of Solivérez (2003). It is also intended to explain the perception of the body, the functions of the body and the body as a machine.
Dominar el mundo privado: Casas inteligentes y razón instrumental.
Authors:   Katholieke Universiteit Leuven (Universidad Católica de Lovaina). (BÉLGICA), Francisco Nan David
Published: June 2021

This paper deals about smarthomes. It analyses them using the instrumental reason concept. It shows how smarthomes develop the instrumental reason at a domestic level. It demonstrates the lack of importance given to subjectivity, the threats of providing a big power to some individuals, the dangers for home private life and the political risks of legitimating an almost complete control of environments.
Foundations, Alan Plaunt and the early days of CBC radio
Authors: Twomey John E.
Published: June 2021

This book is very aptly named, for it was Alan Plaunt, more than any other individual, who set the philosophical and organizational foundations of the CBC and its progenitor, the Canadian Radio Broadcasting Commission.
Plaunt's pivotal role in the genesis of public broadcasting in Canada was initially set out by Michael Nolan as his doctoral study for the University of Western Ontario where today Nolan teaches at the Graduate School of Journalism. CBC Enterprises published Nolan's work along with several other books in the fall of 1986 in celebration of CBC's 50 years of public broadcasting service. The 162 page narrative is enhanced by its thorough footnoting and seven pages of reference sources on Canadian broadcasting history.
The Effect of Different Ratios of Malonic Acid to Plyvinylalcohol on Electrochemical and Mechanical Properties of Polyacrylonitrile Electrospun Separators in Lithium-Ion Batteries
Authors: Khodaverdi Fartash , Javanbakht Mehran , Vaziri Ali , Jahanfar Mehdi
Published: June 2021

The present study aimed to investigate the mechanical, thermal, and electrochemical properties of Polyacrylonitrile (PAN) electrospun separators in the presence of Polyvinylalcohol (PVA) hydrophilic materials and Malonic Acid (MA) crosslinker inside the lithium-ion batteries. The results showed that the M3 modified separator with the MA to PVA+MA (wt./wt.) optimum ratio of 37.5 % had the best performance in all tests. This separator had a value of 3.16 mS/cm in the ion conductivity test. Additionally, it had an electrolyte uptake of 1172 % (2.39 times more than the neat PAN separator) and thermal shrinkage of 7.4 % at 180 °C, where this value was 14.5 % for neat PAN separator at the same experimental condition. Furthermore, the acceptable performance in the battery performance tests was compared with other separators.
Importance of Competences in Communication, as Perceived by Business Leaders
Authors: Karacsony Peter , Bokor Tamás
Published: June 2021

From the perspective of a hierarchically ordered company, the expectations of company leaders concerning their employees' necessary competencies play a greater role than vice versa. This paper light on the expectations of leaders and sub-leaders of micro-, small and medium-sized enterprises concerning the competencies of employees in neighbouring parts of Hungary and Slovakia.The authors' collected 28 scientific papers on the issue of communication competencies in order to map out 21 "common denominators" derived from the combined competence lists. A survey was conducted with 222 respondents to measure the subjective importance assigned to these traits and to observe the respondents' attitudes towards the effectiveness of communication training programmes they had participated in. On the Hungarian side, speech competence proved to be the most crucial competence for business leaders, followed by attention/reflection and interpersonal communication skills. In Slovakia, persuasion was reported to be the most crucial trait, the second most important is the application of confirmation and feedback, and the third is speech competence. In terms of the participants' past communication training experiences, the competences of group communication, assertiveness and leadership skills were reported to have been the main areas of focus. The findings indicate that overall satisfaction with communication training programmes depends on neither the amount of participants' leadership experience nor the companies' field(s) of activity, nor the nationality (i.e. the venue) of the companies. The overall satisfaction rate is 2.53 on a four-grade scale among those who ever attended communication training programmes.
Development of Psychosocial Telenursing Education Stigma of Suspected Covid-19 (Rapid Reactive) Patients
Authors: Tri Wahyuni  , Parliani  , Kharisma Pratama  , Tutur Kardiatun  , Nita Zulfia  , Paudilah  , Gmeliana Adha Sari
Published: June 2021

In the midst of the Covid-19 pandemic, there is one social phenomenon that has the potential to aggravate the situation, namely stigma in patients suspected of Covid-19 or rapid reactive results. The lab results have not actually confirmed that the patient is positive for Covid-19 but the social environment or negative associations of a person or group of people who experience symptoms or bear certain diseases result in stigma against a person. This study aims to find out how the experience and stigma in patients suspected of Covid - 19. This study uses qualitative approach method of phenomenological studies and in-depth interviews  with  telenursing. The number of participants in this study was 10 participants. This study obtained 5 themes, namely physiological experience, psychological experience, biological experience, sociological experience and spiritual experience. The high positive number of Covid-19 in Indonesia makes the emergence of negative stigma of society to patients exposed to Covid-19, not even just Patients who are positive of Covid-19 who get negative stigma, therefore for diagnostic enforcement it takes examination by Molecular Test: Real Time PCR (Polymerase Chain Reaction) method. The sample types used are bronchoalveolar lavage, nasopharyngeal or oropharyngeal swabs, sputum, tracheal aspirate, nasopharyngeal aspirate or nasal wash, and biopsy tissue including from the lungs. Real Time PCR check method is the golden standard for the enforcement of diagnostic Covid - 19.
PREVALENCE AND CORRELATES OF OBESITY IN INDUSTRIAL WORKERS IN ARCTIC RUSSIA
Authors: Syurin S. A. , Gorbanev S. A.
Published: June 2021

Background: Obesity has been consistently reported as a global epidemic representing a significant medical and social problem in many countries. However, the number of studies on this topic from Arctic Russia is still relatively scarce. Aim: To assess the prevalence and correlates of obesity among industrial workers in an Arctic Russian setting. Methods: Altogether, 2 474 workers of a mining and metallurgical enterprise in the Murmansk region participated in a cross-sectional study. The list of studied characteristics complied with the requirements of the Order of the Ministry of Health and Social Development of Russia dated 04/12/2011, No. 302n, as amended on 05/18/2020. In addition, we studied intensity and frequency of leisure time physical activity. Student's unpaired t-tests and chi-squared tests were used for analyses of numeric and categorical variables, respectively. Prevalence ratios (PR) and 95 % confidence interval (CI) were also calculated. Results: The prevalence of obesity was 17.6 % and it was ranked the third most common health problems after myopia and low back pain. Age, female gender, severity of work and number of working years and low leisure time physical activity were associated with obesity. The prevalence of musculoskeletal (PR = 1.11; CI 1.04-1.19) and circulatory (PR = 1.62; CI 1.41-1.86) diseases, disorders of endocrine system, nutrition and metabolism (PR = 2.01; CI 1.48-2.74), including arterial hypertension (PR = 2.11; CI 1.72-2.59) and type 2 diabetes mellitus (PR = 3.14; CI 1.28-7.68) were greater than among non-obese individuals. Obese employees had on average more diseases than their non-obese counterparts (3.41 ± 0.12 vs.2.80 ± 0.06, p < 0.001). Conclusion: Nearly every fifth employee in the study population is obese and have more somatic diseases than non-obese individuals. Our findings warrant development of population-based or occupational programs to prevent obesity and reduce the number of associated problems among industrial workers in Arctic Russia.
EPIGENETIC MARKERS OF THE INFLUENCE OF PARTICULATE MATTER WITH DIFFERENT AERODYNAMIC DIAMETERS ON HUMAN HEALTH: A REVIEW
Authors: Titova A. G. , Zanyatkin I. A. , Volkova A. G. , Nechaev D. N. , Trusov G. A.
Published: June 2021

In this review article we provide an overview of epigenetic markers associated with the effects of particulate matter with different aerodynamic diameters, namely, PM0,1, PM, PM10 and PM2,5-10. The developed list of more than 150 epigenetic signatures of environmental pollutants on different human health conditions may contribute to the development of novel methodological approaches to early detection of diseases in individuals exposed to particulate matter. In addition, this work can become a prerequisite for the development of fundamentally new air purification systems.
Peritonitis meconial pseudoquística por atresia intestinal perforada. Reporte de un caso
Authors: Cabrera Valerio Carlos Manuel , González Niurka , Moreno Reyes Andreina , García Risk Ariadna , Madera Noelia
Published: June 2021

La peritonitis meconial secundaria a perforación intestinal es una complicación temida de la atresia intestinal, puesto que incrementa la morbimortalidad perinatal. Aunque sigue siendo una presentación rara, su diagnóstico debe de hacerse temprano para evitar complicaciones. Presentamos un caso clínico  de un recién nacido de 38 semanas sin antecedentes prenatales indicativos de obstrucción intestinal. Quien presenta vómitos biliosos/ fecaloideos, no meconización a las 12 horas de vida extrauterina, por lo cual  se le realiza radiografía de abdomen de pie y acostada que muestra marcada distensión de asas intestinales, ausencia de aire distal, edema interasas. Se realiza laparotomía exploratoria y se hace yeyunostomía para luego re-intervenirla (second look), encontrando mejoría de asas intestinales, logrando una anastomosis yeyuno-ileal término-terminal.  La operación temprana se puede considerar un factor de importancia para mejorar el resultado de los pacientes con peritonitis por meconio, de igual forma se necesita de un diagnóstico temprano.
Coriocarcinoma no gestacional primario de ovario. A propósito de un caso y revisión de la literatura
Authors: Gonzales-Medina Carlos , Gálvez-Vizcarra Siria , Aguilar-Ramos Pedro , Molina-Maldonado Beatriz , Arenas-Significación Fernando , Alegría-Guerreo Raúl , Paz-Castillo Julio , James-García † Carlos
Published: June 2021

Se presenta el caso clínico de una paciente con diagnóstico de coriocarcinoma primario no gestacional de ovario que corresponde a una neoplasia maligna germinal. Asimismo, se revisa la literatura actualizada del tema haciendo énfasis en la biología molecular, el diagnóstico y el manejo oncológico inicial. Se desarrolló en el Hospital Nacional Dos de Mayo (HNDM) en el servicio de Ginecología Oncológica, Lima, Perú. Se registra el presente caso por su poca casuística en nuestro medio y por el importante valor del criterio oncológico en el manejo de masas anexiales ováricas.
CONCURRENT PRODUCT DEVELOPMENT IN SOFTWARE ENGINEERING: A LITERATURE REVIEW
Authors: Jagani Neelay , Mehta Jai , Mehta Vishant , Nanavati Pankti
Published: June 2021

Concurrent development model which is also
referred to as concurrent engineering, is an approach to
design and develop products where different stages are
executed simultaneously. The product development time
and the time to market are decreased, leading to improved
productivity and reduced costs. In this paper, we will
discuss about the process involved in the development, the
model of organization of the development process, and
further we will focus on various attributes and elements of
concurrent process development and we will also discover
how it finds its application in today’s world.
Disclosure & risk management
Authors: Beunza Daniel , Henshaw Kira , Agarwala Matthew , Perkins-Kirkpatrick Sarah , Battiston Stefano , Fiedler Tanya , Zhu Wei , Bugden Emily , Sannapureddy Mia , Trecroci Carmine
Published: June 2021

Standardized and transparent disclosure of investors’ exposure to climate-related financial risks is crucial to decrease market uncertainty and support climate-financial risk assessment. This session will discuss experiences and challenges relating to financial and non-financial disclosure, their implications for climate-financial risk assessment and opportunities to overcome them.
Student session: The Importance of Locally-led Adaptation and Resilience in the face of Climate Change
Authors: Causley Jake , Dookie Denyse , Sembayeva Aliya , Effiong Cyril , De Boer Anke , Ibrahim Ulfath , Uba Salisu
Published: June 2021

This session will provide an exploration of locally-led adaptation and resilience strategies.
New evidence on mitigation solutions
Authors: Nelson Jenny , Xiao Christina , Honegger Matthias , DeFreese Michelle , Cain Michelle , Jung Thea
Published: June 2021

This session will survey global evidence and examples of best practice on mitigation solutions and enabling conditions for mitigation.
Capacity Building and Knowledge Transfer for Nature-based Solutions
Authors: Park Alison , Rowse Claudia , Reay Dave , Dinesh Dhanush , Zahid Zainab
Published: June 2021

This session will discuss the crucial role of education, skills development and shared learning in realising sustainable Nature-based Solutions around the world. It will examine the role of youth action and empowerment, highlight existing good practice and emerging challenges in the agriculture sector, and provide insights into the opportunities for enhancing learning and skills to boost employment and secure livelihoods through Nature-based Solutions.
The road to COP26 - developing the Paris Agreement Rulebook
Authors: de Correa Fabiano , Minnerop Petra , Oral Nilufer , Voigt Christina
Published: June 2021

The UN Climate Change Executive Secretary, Patricia Espinosa, set out four key elements to measure success at UN COP26 Climate Change Conference. These four elements are that 1. the promises are kept to mobilise $100 billion in climate finance annually by 2020; 2. governments wrap up outstanding issues to fully implement the Paris Agreement; 3. countries lower emissions and raise climate ambition (mitigation, adaptation and resilience); 4. no voice should be left behind. She called 2021 the most important year since the adoption of the Paris Agreement for tackling climate change through action within this legal framework. Accelerated action is needed under all five themes of the UK-Italy Presidency, and engagement of all stakeholders will be important. In this parallel session, we will discuss some of the relevant legal issues for the finalisation of the Paris Agreement Rulebook during the Climate Exp0.
Adapting robustly to climate change
Authors: Roberts Debra , Manes Fausto , Townend Ian , Weru Jane , Hinkel Jochen , Waruingi Lucy , Losasso Mario , Haasnoot Marjolijn , Tira Maurizio , Leach Melissa , Hallegatte Stéphane , Hill Jane , Mumba Musonda
Published: June 2021

This session will critically examine new and emerging approaches to adaptation using three contrasting themes to illustrate key issues. The session will comprise 3 panels on: Conservation/biodiversity, Coastal Systems and Urban Systems. Each panel will address the common themes of (a) co-benefits and transformation issues; (b) how to handle uncertainty; (c) justice dimensions; (d) links between systems; and (e) working across scales – national policy to local implementation.
Scaling up protection, restoration and connection of key ecosystems across UK landscapes
Authors: Wheeler Ben , Cadman Carolyn , Coomes David , Glücksman Edvard , Roberts Stuart
Published: June 2021

This session will explore scaling up Nature-based solutions in different contexts including woodland, agriculture, wildlife and human health.
Socially equitable green recovery
Authors: Wdowin Julia , Press Melea , Foxon Timothy , Cheung Wai Lok , Forrest Steven
Published: June 2021

In this session, speakers will present their research followed by a discussion on what measures beyond economics are critical in a just and socially equitable green recovery.
Closing (Policy): Opportunity & finance roundtable
Authors: Jones Aled , Alessi Lucia , Grobmyer Mark , Billio Monica , Kumar Neha , Kerr Tom
Published: June 2021

The requirements of a transition to a carbon neutral future by 2050 and, in the case of the EU, a 55% reduction in greenhouse gas emissions by 2030, offer a wide variety of opportunities for households, firms and society at large to avail of new consumption, investment and production practices. This panel discussion will explore concrete, implemental policies and actions of how the global financial system can be mobilized to support this radical change and how global finance can work for the climate and biodiversity.
Student session - Is it too late to mitigate climate change? What can you do?
Authors: Causley Jake , Velenturf Anne , Williams Joshua , Abbati Alessia , Fisher Ben , Larkin Collette , Onyenma Favour , Doran Hannah , Smith Isabel
Published: June 2021

This session will provide ‘an introduction to mitigating solutions’ such as carbon sources and sinks, heat sources and sinks, and reducing our individual carbon footprints.
Nature-based Solutions Research Showcase 1
Authors: Marchant Rob , Guizar Coutiño Alejandro , Weber Anne-Kathrin , Barnes David , DeClerck Fabrice , Boano Fulvio , Rakotonarivo Sarobidy
Published: June 2021

In this session speakers will present their research covering a range of topics within the Nature-based solutions theme including, agriculture, biodiversity, REDD+, off-setting and water management.
Localising the Circular Economy: short green value chains for protecting the environment while catering for a growing population
Authors: Venuto Alex , Krishnan Anantha , Weem Camilla , Werna Edmundo , Prentice Phil
Published: June 2021

The session aims to bring key urban stakeholders together to establish dialogue on cities and circular economies. City leaders, urban professionals, financial institutions, community groups and academics will come together to present good and replicable examples and discuss practical approaches to implementing circular economies. The session will provide thoughts for decoupling economic activity from the consumption of finite resources locally and globally, and reducing waste out of the system - maximizing the value of resources by keeping them in use for as long as possible.
Student session - Leaving no-one behind: Ensuring a just green recovery post-COVID-19 in the Global North and Global South
Authors: Causley Jake , King Morgan , Stevenson Bea , Boetner Ted , Agrawal Kopal
Published: June 2021

This session will discuss common ground, elaborate on differences/challenges between the regions, and offer a constructive space for looking forward to a North/South recovery.
Student session - Nature for planet and people: the importance of preserving and regenerating natural systems for both climate and human wellbeing
Authors: Causley Jake , Davies Faye , Ukonze Frances Ifeoma , Jackson Janet , Merce Pomares Palau Maria , Smith Pete
Published: June 2021

This session will discuss the UN Sustainable Development Goals (SDGs), ecological resistance in relation to nature-based solutions and the effect of nature-based solutions on human wellbeing.
Economy-wide impacts of green recovery
Authors: Cameron Catherine , Peñasco Cristina , Malerba Daniele , Forster Piers , van Hummelen Stijn
Published: June 2021

In this session on economy-wide impacts of green recovery, speakers will present their modelling research followed by discussion on the importance of this current pivotal point in the global economy.
Ser71 Phosphorylation Inhibits Actin-Binding of Profilin-1 and Its Apoptosis-Sensitizing Activity
Authors: Wang Faliang , Zhu Cuige , Cai Shirong , Boudreau Aaron , Kim Sun-Joong , Bissell Mina , Shao Jieya
Published: June 2021

The essential actin-binding factor profilin-1 (Pfn1) is a non-classical tumor suppressor with the abilities toboth inhibit cellular proliferation and augment chemotherapy-induced apoptosis. Besides actin, Pfn1 interacts with proteins harboring the poly-L-proline (PLP) motifs. Our recent work demonstrated that both nuclear localization and PLP-binding are required for tumor growth inhibition by Pfn1, and this is at least partially due to Pfn1 association with the PLP-containing ENL protein in the Super Elongation Complex (SEC) and the transcriptional inhibition of pro-cancer genes. In this paper, by identifying a phosphorylation event of Pfn1 at Ser71capable of inhibiting its actin-binding and nuclear export, we providein vitroandin vivoevidence that chemotherapy-induced apoptotic sensitization by Pfn1 requires its cytoplasmic localization and actin-binding. With regard to tumor growth inhibition byPfn1, our data indicate a requirement for dynamic actin association and dissociation rendered by reversible Ser71phosphorylation and dephosphorylation. Furthermore, genetic and pharmacological experiments showed that Ser71of Pfn1 can be phosphorylated by protein kinase A (PKA). Taken together, our data provide novel mechanistic insights into the multifaceted anticancer activities of Pfn1 and how they are spatially-defined in the cell and differentially regulated by ligand-binding.
Case Report: Prenatal Diagnosis and Treatment of Fetal Autoimmune-Associated First-Degree Atrioventricular Block: First Report From China
Authors: Tang Changqing , Yu Haiyan , Shao Shuran , Hua Yimin , Chen Maoli , Zhu Qi , Li Yifei , Zhou Kaiyu , Wang Chuan
Published: June 2021

Background: The rapid progression from fetal first-degree atrioventricular block (AVB) to third-degree AVB had been reported. However, how to define fetal first-degree AVB with proper technique and the necessity of the treatment in utero for fetal autoimmune-associated first-degree AVB are still controversial.

Purpose: To explore the diagnosis and the effect of treatment for fetal first-degree AVB.

Cases Presentation: Four pregnant women with positive autoantibodies anti-SSA/Ro were admitted into our hospital with complaints of rapid prolonged atrioventricular (AV) intervals of their fetuses. Fetal AV intervals were re-measured by tissue Doppler imaging (TDI) from the onset of atrial contraction to ventricular systole (Aa-Sa), which were 170 ms (case 1-twin A), 160 ms (case 1-twin B), 163 ms (case 2) and 172 ms (case 3) and 170 ms (case 4), respectively. The histories of medication usage or infection during gestation were denied. Amniotic fluid genetic screenings and virological tests were negative in all cases. No structural cardiac disorders were found and the cardiovascular profile scores were 10 for each fetus. Oral dexamethasone (initial dose of 4.5 mg daily) and hydroxychloroquine (200 mg bid) plus weekly follow-up surveillance were suggested. The dosage of dexamethasone was adjusted according to the changes of the AV intervals and fetal development of biparietal diameters (BPD) and femur lengths (FL). All fetal AV intervals were controlled well. Maternal and fetal adverse effects were noted as diabetes in 1 mother and growth retardation in all fetuses. All fetuses were delivered via cesarean section at 35+4, 37, 38, and 37+1 gestational weeks, with 10 scores of Apgar score. Postnatally, positive anti-SSA/Ro was found in all neonates. However, there were no clinical or laboratory evidence of neonatal lupus syndrome. No abnormal signs were found on postnatal electrocardiogram and echocardiography for all neonates. With a follow-up of 8–53 months, there was no progression of disease and all infants demonstrated normal physical, mental, and motor development.

Conclusion: Prenatal treatment for fetal autoimmune-associated first-degree AVB could be an alternative. Strict surveillance and timely adjustment of the treatment according to the conditions of the mother and the fetus are indicated. Further studies are necessary to prove our concept.
Parametric Estimation of Reference Signal Intensity for Semi-Quantification of Tau Deposition: A Flortaucipir and [18F]-APN-1607 Study
Authors: Zhang Huiwei , Wang Min , Lu Jiaying , Bao Weiqi , Li Ling , Jiang Jiehui , Zuo Chuantao ,   and Alzheimer’s Disease Neuroimaging Initiative
Published: June 2021

Background

Tau positron emission tomography (PET) imaging can reveal the pathophysiology and neurodegeneration that occurs in Alzheimer’s disease (AD) in vivo. The standardized uptake value ratio (SUVR) is widely used for semi-quantification of tau deposition but is susceptible to disturbance from the reference region and the partial volume effect (PVE). To overcome this problem, we applied the parametric estimation of reference signal intensity (PERSI) method—which was previously evaluated for flortaucipir imaging—to two tau tracers, flortaucipir and [18F]-APN-1607.

Methods

Two cohorts underwent tau PET scanning. Flortaucipir PET imaging data for cohort I (65 healthy controls [HCs], 60 patients with mild cognitive impairment [MCI], and 12 AD patients) were from the AD Neuroimaging Initiative database. [18F]-APN-1607 ([18F]-PM-PBB3) PET imaging data were for Cohort II, which included 21 patients with a clinical diagnosis of amyloid PET-positive AD and 15 HCs recruited at Huashan Hospital. We used white matter (WM) postprocessed by PERSI (PERSI-WM) as the reference region and compared this with the traditional semi-quantification method that uses the whole cerebellum as the reference. SUVRs were calculated for regions of interest including the frontal, parietal, temporal, and occipital lobes; anterior and posterior cingulate; precuneus; and Braak I/II (entorhinal cortex and hippocampus). Receiver operating characteristic (ROC) curve analysis and effect sizes were used to compare the two methods in terms of ability to discriminate between different clinical groups.

Results

In both cohorts, regional SUVR determined using the PERSI-WM method was superior to using the cerebellum as reference region for measuring tau retention in AD patients (e.g., SUVR of the temporal lobe: flortaucipir, 1.08 ± 0.17 and [18F]-APN-1607, 1.57 ± 0.34); and estimates of the effect size and areas under the ROC curve (AUC) indicated that it also increased between-group differences (e.g., AUC of the temporal lobe for HC vs AD: flortaucipir, 0.893 and [18F]-APN-1607: 0.949).

Conclusion

The PERSI-WM method significantly improves diagnostic discrimination compared to conventional approach of using the cerebellum as a reference region and can mitigate the PVE; it can thus enhance the efficacy of semi-quantification of multiple tau tracers in PET scanning, making it suitable for large-scale clinical application.