bluuebunny/crossref_metadata_2025 huggingface dataset:
Recent Advances on Visible Light Metal-Based Photocatalysts for Polymerization under Low Light Intensity
Authors: Dumur Frédéric
Published: August 2019

In recent years, polymerization processes activated by light have attracted a great deal of interest due to the wide range of applications in which this polymerization technique is involved. Parallel to the traditional industrial applications ranging from inks, adhesives, and coatings, the development of high-tech applications such as nanotechnology and 3D-printing have given a revival of interest to this polymerization technique known for decades. To initiate a photochemical polymerization, the key element is the molecule capable to interact with light, i.e., the photoinitiator and more generally the photoinitiating system, as a combination of several components is often required to create the reactive species responsible for the polymerization process. With the aim of reducing the photoinitiator content while optimizing the polymerization yield and/or the polymerization speed, photocatalytic systems have been developed, enabling the photosensitizer to be regenerated during the polymerization process. In this review, an overview of the photocatalytic systems developed for polymerizations carried out under a low light intensity and visible light is provided. Over the years, a wide range of organometallic photocatalysts has been proposed, addressing both the polymerization efficiency and/or the toxicity, as well as environmental issues.
Synthesis of Au–Ag Alloy Nanoparticle-Incorporated AgBr Crystals
Authors: Naya Shin-ichi , Fujishima Musashi , Tada Hiroaki
Published: September 2019

Nanoscale composites consisting of silver and silver halide (Ag–AgX, X = Cl, Br, I) have attracted much attention as a novel type of visible-light photocatalyst (the so-called plasmonic photocatalysts), for solar-to-chemical transformations. Support-free Au–Ag alloy nanoparticle-incorporated AgBr crystals (Au–Ag@AgBr) were synthesized by a photochemical method. At the initial step, Au ion-doped AgBr particles were prepared by adding an aqueous solution of AgNO3 to a mixed aqueous solution of KBr and HAuBr4. At the next step, UV-light illumination (λ = 365 nm) of a methanol suspension of the resulting solids yielded Au–Ag alloy nanoparticles with a mean size of approximately 5 nm in the micrometer-sized AgBr crystals. The mole percent of Au to all the Ag in Au–Ag@AgBr was controlled below < 0.16 mol% by the HAuBr4 concentration in the first step. Finite-difference time-domain calculations indicated that the local electric field enhancement factor for the alloy nanoparticle drastically decreases with an increase in the Au content. Also, the peak of the localized surface plasmon resonance shifts towards longer wavelengths with increasing Au content. Au–Ag@AgBr is a highly promising plasmonic photocatalyst for sunlight-driven chemical transformations due to the compatibility of the high local electric field enhancement and sunlight harvesting efficiency.
Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins
Authors: Ramirez Peter W. , Sharma Shilpi , Singh Rajendra , Stoneham Charlotte A. , Vollbrecht Thomas , Guatelli John
Published: September 2019

The plasma membrane is a site of conflict between host defenses and many viruses. One aspect of this conflict is the host’s attempt to eliminate infected cells using innate and adaptive cell-mediated immune mechanisms that recognize features of the plasma membrane characteristic of viral infection. Another is the expression of plasma membrane-associated proteins, so-called restriction factors, which inhibit enveloped virions directly. HIV-1 encodes two countermeasures to these host defenses: The membrane-associated accessory proteins Vpu and Nef. In addition to inhibiting cell-mediated immune-surveillance, Vpu and Nef counteract membrane-associated restriction factors. These include BST-2, which traps newly formed virions at the plasma membrane unless counteracted by Vpu, and SERINC5, which decreases the infectivity of virions unless counteracted by Nef. Here we review key features of these two antiviral proteins, and we review Vpu and Nef, which deplete them from the plasma membrane by co-opting specific cellular proteins and pathways of membrane trafficking and protein-degradation. We also discuss other plasma membrane proteins modulated by HIV-1, particularly CD4, which, if not opposed in infected cells by Vpu and Nef, inhibits viral infectivity and increases the sensitivity of the viral envelope glycoprotein to host immunity.
In Situ Fabrication of a Superhydrophobic ORMOSIL Coating on Wood by an Ammonia–HMDS Vapor Treatment
Authors: Yue Decai , Feng Qifan , Huang Xuanting , Zhang Xinxiang , Chen Hanxian
Published: August 2019

A superhydrophobic ORMOSIL (organically modified silicate) coating was in situ fabricated on a wood surface by ammonia–hexamethylisilazane (HMDS) vapor treatment. The wood was immerged in tetraethoxysilane (TEOS), and then the TEOS absorbed on the wood surface was hydrolyzed and condensed to hydrophobic SiO2 nanoparticles with ammonia and HDMS vapor treatment. The effect of the treatment temperature and time on the hydrophobicity of wood was investigated. At a treatment temperature of 50 °C, a superhydrophobic surface was achieved on the wood with a treatment time longer than 2 h. SEM images indicated that there were SiO2 nanoparticles fabricated on the wood surface, and FTIR revealed that the hydrophobic –Si(CH3)3 groups were incorporated on the wood surface. The ORMOSIL-modified wood possessed improved liquid repellency. The water absorption decreased significantly from 72.3% to 31.9% after modification.
Protective Mechanism of Silane on Concrete upon Marine Exposure
Authors: Li Shaochun , Zhang Wenjuan , Liu Jun , Hou Dongshuai , Geng Yongjuan , Chen Xu , Gao Yan , Jin Zuquan , Yin Bing
Published: September 2019

Due to the high chloride ion concentration in marine environments, chloride ions can penetrate into concrete, along with the transportation of water molecules, and thus, cause rebar corrosion. This is an important reason for the decrease in the concrete durability. In this paper, by means of the sol–gel synthesis method, a silane emulsion, a silane compound emulsion, and silane compound gel were prepared by using isobutyl triethoxysilane and ethyl orthosilicate (TEOS) as the main raw materials. These silane materials were coated on a concrete surface and then placed in the marine exposure sites of Wheat Island, in Qingdao, for one year. The results show that these silane materials can effectively inhibit the chloride ions transporting in concrete. Upon the increase of the exposure time, the protection ability of the silane emulsion declined gradually, while the silane compound emulsion had stable protective effects. In comparison with the permeability coefficient of chloride ions in the blank test block, the permeability coefficient of chloride ions in the test block coated with the silane emulsion, the composition of silane emulsion, and silane compound gel fell off around 20%, 30%, and 50%, respectively. The test results indicate that the three kinds of protective materials have good inhibition abilities against chloride ion transportation, on which the compound gel had the best effect.
Long-Term Stable Solid-State Dye-Sensitized Solar Cells Assembled with Solid-State Polymerized Hole-Transporting Material
Authors: Jang Yu , Thogiti Suresh , Lee Kang-yong , Kim Jae
Published: August 2019

The long-term stability of liquid-state dye-sensitized solar cells (liquid-DSSCs) is a primary problem for the upscaling and commercialization of this technology. The solid-state dye-sensitized solar cell (ss-DSSC) has been instigated to overcome the liquid-DSSC’s inherent production and instability issues and advancement has been made to achieve low-cost high-power conversion efficiency. The photovoltaic performance of ruthenium-based complex Z907 dye was studied in ss-DSSCs using a solid-state polymerized conductive polymer as hole-transporting material (HTM). We investigated the long-term stability of both liquid and solid-state DSSCs and the findings revealed an improved photovoltaic performance and long-term stability of ss-DSSC. This mainly depends on the transport phenomena of the HTM throughout the interface. The present results show a pavement for manufacturing highly stable and inexpensive ss-DSSC and the practical use is promising.
Autowave Physics of Material Plasticity
Authors: Zuev Lev , Barannikova Svetlana
Published: September 2019

The notions of plastic flow localization are outlined in the paper. It is shown that each type of localized plasticity pattern corresponds to a definite stage of deformation hardening. In the course of plastic flow development, a changeover in the types of localization patterns occurs. The types of localization patterns are limited in number: four pattern types are all that can be expected. A correspondence was set up between the emergent localization pattern and the respective flow stage. It is found that the localization patterns are manifestations of the autowave nature of plastic flow localization process, with each pattern type corresponding to a definite mode of autowave. In the course of plastic flow development, the following modes of autowaves will form in the following sequence: switching autowave → phase autowave → stationary dissipative structure → collapse of the autowave. Of particular interest are the phase autowave and the respective pattern observed. Propagation velocity, dispersion, and grain size dependence of wavelength were determined experimentally for the phase autowave. An elastic-plastic strain invariant was also introduced to relate the elastic and plastic properties of the deforming medium. It is found that the autowave characteristics follow directly from this invariant.
Cone-Beam Computed Tomography in Orthodontics
Authors: Abdelkarim Ahmad
Published: September 2019

Unlike patients receiving implants or endodontic treatment, most orthodontic patients are children who are particularly sensitive to ionizing radiation. Cone-beam computed tomography (CBCT) carries risks and benefits in orthodontics. The principal risks and limitations include ionizing radiation, the presence of artifacts, higher cost, limited accessibility, and the need for additional training. However, this imaging modality has several recognized indications in orthodontics, such as the assessment of impacted and ectopic teeth, assessment of pharyngeal airway, assessment of mini-implant sites, evaluation of craniofacial abnormalities, evaluation of sinus anatomy or pathology, evaluation of root resorption, evaluation of the cortical bone plate, and orthognathic surgery planning and evaluation. CBCT is particularly justified when it brings a benefit to the patient or changes the outcome of the treatment when compared with conventional imaging techniques. Therefore, CBCT should be considered for clinical orthodontics for selected patients. Prescription of CBCT requires judicious and sound clinical judgment. The central question of this narrative review article is: when does CBCT add value to the practice of orthodontics? To answer this question, this article presents discussion on radiation dosage of CBCT and other imaging techniques used in orthodontics, limitations of CBCT in orthodontics, justifying the use of CBCT in orthodontics, and the benefits and evidence-based indications of CBCT in orthodontics. This review summarizes the central themes and topics in the literature regarding CBCT in orthodontics and presents ten orthodontic cases in which CBCT proved to be valuable.
Impact of Must Replacement and Hot Pre-Fermentative Maceration on the Color of Uruguayan Tannat Red Wines
Authors: Piccardo Diego , González-Neves Gustavo , Favre Guzman , Pascual Olga , Canals Joan Miquel , Zamora Fernando
Published: September 2019

This research aimed to evaluate the impact of different options for winemaking on the color composition of Uruguayan Tannat red wines. The techniques evaluated were the substitution of ripe grape juice with immature grape juice and the heating of the crushed grapes before fermentation, called must replacement and hot pre-fermentative maceration, respectively. These procedures were proposed to reduce the alcohol content and increase the phenolic composition of the wine, according to the expected effects of climate change and current trends in consumer preferences. The investigation was made over three consecutive years (2016, 2017, and 2018). Both winemaking techniques allow the enhancement of the chromatic characteristics of wines via the modification of the phenolic composition. Additionally, such techniques allow the overcoming of the well-known limitations in the extractability of anthocyanins presented by the Tannat cultivar. Hot pre-fermentative maceration increases the proportion of the most oxidizable molecules delphinidin-3-O-glucoside, cyanidin-3-O-glucoside, and petunidin-3-O-glucoside, suggesting heat inactivation of polyphenoloxidases enzymes. Must replacement and hot pre-fermentative maceration are technological alternatives that could significantly improve the intensity and chromatic characteristics of red wines.
Synthesis and Characterisation of Novel Temperature and pH Sensitive Physically Cross-Linked Poly(N-vinylcaprolactam-co-itaconic Acid) Hydrogels for Drug Delivery
Authors: Fallon Megan , Halligan Shane , Pezzoli Romina , Geever Luke , Higginbotham Clement
Published: August 2019

Previous studies involving poly N-vinylcaprolactam (PNVCL) and itaconic acid (IA) have synthesised the hydrogels with the presence of a solvent and a crosslinker, producing chemically crosslinked hydrogel systems. In this study, however, temperature sensitive PNVCL was physically crosslinked with a pH-sensitive comonomer IA through ultraviolet (UV) free-radical polymerization, without the presence of a solvent, to produce hydrogels with dual sensitivity. The attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy indicated successful polymerisation of the hydrogels. The temperature and pH sensitivity of the hydrogels was investigated. The lower critical solution temperature (LCST) of the gels was determined using the UV spectrometry and it was found that the incorporation of IA decreased the LCST. Rheology was conducted to investigate the mechanical and viscoelastic properties of the hydrogels, with results indicating IA that enhances the mechanical properties of the gels. Swelling studies were carried out at ~20 °C and 37 °C in different buffer solutions simulating the gastrointestinal tract (pH 2.2 and pH 6.8). In acidic conditions, the gels showed gradual increase in swelling while remaining structurally intact. While in basic conditions, the gels had a burst in swelling and began to gradually degrade after 30 min. Results were similar for drug release studies. Acetaminophen was incorporated into the hydrogels. Drug dissolution studies were carried out at 37 °C in pH 2.2 and pH 6.8. It was found that <20% of acetaminophen was released from the gels in pH 2.2, whereas the maximum drug released at pH 6.8 was 74%. Cytotoxicity studies also demonstrated the hydrogels to be highly biocompatible. These results indicate that physically crosslinked P(NVCL-IA) gels possess dual pH and temperature sensitive properties, which may be beneficial for biomedical applications such as drug delivery.
Preparation of ETS-10 Microporous Phase Pellets with Color Change Properties
Authors: De Luca Pierantonio , Mastroianni Carmelo , Siciliano Carlo , Nagy Janos B. , Macario Anastasia
Published: September 2019

The main scope of the present work is to synthesize pH-responsive Engelhard titanium silicate (ETS)-10 phase crystalline pellets through the smart modification of a synthetic process which was previously applied to the preparation of other phases. The original preparative method, which envisages the use of the same initial synthesis as a binder for the preparation of pellets, was modified by adding an appropriate pH indicator to a number of systems subject to this investigation. It should be noted that the modified process was never before used to give access to pH-responsive ETS-10 phase pellets, and it is disclosed here for the first time. The study started from the definition of the best experimental conditions, which were optimized by analyzing the effects of temperature and system composition. The addition of the pH indicator did not alter the physicochemical characteristics and reactivity of the system. The pH-responsive ETS-10 phase crystalline pellets were characterized by an adequate mechanical strength and by a high capability to change color. The latter aspect can be particularly useful when this material is used in catalytic processes whose performance is strictly dependent on the pH value. The amount of gel used, as well as the working temperature, were the main critical parameters to be controlled during the preparation of pH-responsive ETS-10 phase crystalline pellets. The pellets were fully characterized by X-ray diffraction in order to investigate and identify the possible phases, and by using a hardness tester to measure the compressive strength. Finally, toning tests were performed.
Natural Variation and Domestication Selection of ZmPGP1 Affects Plant Architecture and Yield-Related Traits in Maize
Authors: Li Pengcheng , Wei Jie , Wang Houmiao , Fang Yuan , Yin Shuangyi , Xu Yang , Liu Jun , Yang Zefeng , Xu Chenwu
Published: August 2019

ZmPGP1, involved in the polar auxin transport, has been shown to be associated with plant height, leaf angle, yield traits, and root development in maize. To explore natural variation and domestication selection of ZmPGP1, we re-sequenced the ZmPGP1 gene in 349 inbred lines, 68 landraces, and 32 teosintes. Sequence polymorphisms, nucleotide diversity, and neutral tests revealed that ZmPGP1 might be selected during domestication and improvement processes. Marker–trait association analysis in inbred lines identified 11 variants significantly associated with 4 plant architecture and 5 ear traits. SNP1473 was the most significant variant for kernel length and ear grain weight. The frequency of an increased allele T was 40.6% in teosintes, and it was enriched to 60.3% and 89.1% during maize domestication and improvement. This result revealed that ZmPGP1 may be selected in the domestication and improvement process, and significant variants could be used to develop functional markers to improve plant architecture and ear traits in maize.
Copula-Based Bivariate Flood Risk Assessment on Tarbela Dam, Pakistan
Authors: Naz Saba , Ahsanuddin Muhammad , Inayatullah Syed , Siddiqi Tanveer , Imtiaz Muhammad
Published: August 2019

Flooding from the Indus river and its tributaries has regularly influenced the region of Pakistan. Therefore, in order to limit the misfortune brought about by these inevitable happenings, it requires taking measures to estimate the occurrence and effects of these events. The current study uses flood frequency analysis for the forecast of floods along the Indus river of Pakistan (Tarbela). The peak and volume are the characteristics of a flood that commonly depend on one another. For progressively proficient hazard investigation, a bivariate copula method is used to measure the peak and volume. A univariate analysis of flood data fails to capture the multivariate nature of these data. Copula is the most common technique used for a multivariate analysis of flood data. In this paper, four Archimedean copulas have been tried using the available information, and in light of graphical and measurable tests, the Gumbel Hougaard copula was found to be most appropriate for the data used in this paper. The primary (TAND, TOR), conditional and Kendall return periods have been also determined. The copula method was found to be a powerful method for the distribution of marginal variables. It also gives the Kendall return period for the multivariate analysis the consequences of flooding.
Assessing the Mental Health, Physical Activity Levels, and Resilience of Today’s Junior College Students in Self-Financing Institutions
Authors: Chow Susan Ka Yee , Choi Edward Kwok Yiu
Published: September 2019

In recent decades, the number of adolescents and young adults with poor mental health has been increasing, particularly among students in tertiary institutions. This study investigates the physical activities, resilience, and mental health status of junior college students in Hong Kong. The questionnaire consisted of demographic characteristics, the Positive Mental Health Scale, the Brief Resilience Scale, and the Godin-Shephard Leisure-Time Physical Activity Questionnaire. Four hundred and sixteen students participated in the study. The results showed a moderate positive correlation (r = 0.485) between resilience and mental health, and a low positive correlation (r = 0.258) between resilience and physical activity. The one-way analysis of variance (ANOVA) with a post hoc test showed that arts students engaged in more physical activity than students from other disciplines. A multiple regression analysis was used to examine the predictors of a positive mental health status. The significant predictors are: resilience (β = 0.704; 95% CI = 0.575–0.833; P < 0.001), physical activity score (β = 0.032; 95% CI = 0.016–0.048; P < 0.001), the male gender (β = 1.035, 95% CI = 0.171–1.900; P < 0.05), and students’ enrollment in a health science discipline (β = 1.052, 95% CI = 0.175–1.930; P < 0.05). Preventive measures, such as strengthening resilience, a broad curriculum and taking note of the demographic and cognitive characteristics of students are essential for improving the mental health of freshmen in colleges.
Crime Geographical Displacement: Testing Its Potential Contribution to Crime Prediction
Authors: Wang Zengli , Liu Lin , Zhou Hanlin , Lan Minxuan
Published: September 2019

Crime geographical displacement has been examined in many Western countries. However, little is known about its existence, distribution, and potential predictive ability in large cities in China. Compared to the existing research, this study contributes to the current research in three ways. (1) It provides confirmation that crime geographical displacement exists in relation to burglaries that occur in a large Chinese city. (2) A crime geographical displacement detector is proposed, where significant displacements are statistically detected and geographically displayed. Interestingly, most of the displacements are not very far from one another. These findings confirm the inferences in the existing literature. (3) Based on the quantitative results detected by the crime geographical displacement detector, a crime prediction method involving crime geographical displacement patterns could improve the accuracy of the empirical crime prediction method by 7.25% and 3.1 in the capture rate and prediction accuracy index (PAI), respectively. Our current study verifies the feasibility of crime displacement for crime prediction. The feasibility of the crime geographical displacement detector and results should be verified in additional areas.
On the Use of Single-, Dual-, and Quad-Polarimetric SAR Observation for Landslide Detection
Authors: Park Sang-Eun , Lee Sun-Gu
Published: September 2019

Remote sensing technologies, particularly with Synthetic Aperture Radar (SAR) system, can provide timely and critical information to assess landslide distributions over large areas. Most space-borne SAR systems have been operating in different polarimetric modes to meet various operational requirements. This study aims to discuss how much detectability can be expected in the landslide map produced from the single-, dual-, and quad-polarization modes of observation. The experimental analysis of the characteristic changes of PALSAR-2 signals showed that quad-polarization parameters indicating signal depolarization properties revealed noticeable landslide-induced temporal changes for all local incidence angle ranges. To produce a landslide map, a simple change detection method based on characteristic scattering properties of landslide areas was proposed. The accuracy assessment results showed that the depolarization parameters, such as the co-pol coherence and polarizing contribution, can identify areas affected by landslides with a detection rate of 60%, and a false-alarm rate of 5%. On the other hand, the single- or dual-pol parameters can only be expected to provide half the accuracy with significant false-alarms in areas with temporal variations independent of landslides.
Least Squares Consensus for Matching Local Features
Authors: Zhang Qingming , Shi Buhai , Xu Haibo
Published: September 2019

This paper presents a new approach to estimate the consensus in a data set. Under the framework of RANSAC, the perturbation on data has not been considered sufficiently. We analysis the computation of homography in RANSAC and find that the variance of its estimation monotonically decreases when the size of sample increases. From this result, we carry out an approach which can suppress the perturbation and estimate the consensus set simultaneously. Different from other consensus estimators based on random sampling methods, our approach builds on the least square method and the order statistics and therefore is an alternative scheme for consensus estimation. Combined with the nearest neighbour-based method, our approach reaches higher matching precision than the plain RANSAC and MSAC, which is shown in our simulations.
Early Changes in Pain Acceptance Predict Pain Outcomes in Interdisciplinary Treatment for Chronic Pain
Authors: Probst Thomas , Jank Robert , Dreyer Nele , Seel Stefanie , Wagner Ruth , Hanshans Klaus , Reyersbach Renate , Mühlberger Andreas , Lahmann Claas , Pieh Christoph
Published: September 2019

Studies have shown that pain acceptance is associated with a better pain outcome. The current study explored whether changes in pain acceptance in the very early treatment phase of an interdisciplinary cognitive-behavioral therapy (CBT)-based treatment program for chronic pain predict pain outcomes. A total of 69 patients with chronic, non-malignant pain (at least 6 months) were treated in a day-clinic for four-weeks. Pain acceptance was measured with the Chronic Pain Acceptance Questionnaire (CPAQ), pain outcomes included pain intensity (Numeric Rating Scale, NRS) as well as affective and sensory pain perception (Pain Perception Scale, SES-A and SES-S). Regression analyses controlling for the pre-treatment values of the pain outcomes, age, and gender were performed. Early changes in pain acceptance predicted pain intensity at post-treatment measured with the NRS (B = −0.04 (SE = 0.02); T = −2.28; p = 0.026), affective pain perception at post-treatment assessed with the SES-A (B = −0.26 (SE = 0.10); T = −2.79; p = 0.007), and sensory pain perception at post-treatment measured with the SES-S (B = −0.19 (SE = 0.08); T = −2.44; p = 0.017). Yet, a binary logistic regression analysis revealed that early changes in pain acceptance did not predict clinically relevant pre-post changes in pain intensity (at least 2 points on the NRS). Early changes in pain acceptance were associated with pain outcomes, however, the impact was beneath the threshold defined as clinically relevant.
The Emerging Role of NANOG as an Early Cancer Risk Biomarker in Patients with Oral Potentially Malignant Disorders
Authors: de Vicente Juan C. , Rodríguez-Santamarta Tania , Rodrigo Juan P. , Allonca Eva , Vallina Aitana , Singhania Anusha , Donate-Pérez del Molino Paula , García-Pedrero Juana M.
Published: September 2019

NANOG, a key regulator of pluripotency and self-renewal in embryonic and adult stem cells, is frequently overexpressed in multiple cancers, including oral squamous cell carcinoma (OSCC). It has been frequently associated with poor outcomes in epithelial cancers, and recently implicated in laryngeal tumorigenesis. On this basis, we investigated the role of NANOG protein expression as an early cancer risk biomarker in oral potentially malignant disorders (OPMD), and the impact on prognosis and disease outcomes in OSCC patients. NANOG expression was evaluated by immunohistochemistry in 55 patients with oral epithelial dysplasia, and 125 OSCC patients. Correlations with clinical and follow-up data were assessed. Nuclear NANOG expression was detected in 2 (3.6%) and cytoplasmic NANOG expression in 9 (16.4%) oral dysplasias. NANOG expression increased with the grade of dysplasia. Cytoplasmic NANOG expression and the histopathological grading were significantly correlated with oral cancer risk, although dysplasia grading was the only significant independent predictor of oral cancer development in multivariate analyses. Cytoplasmic NANOG expression was also detected in 39 (31%) OSCC samples. Positive NANOG expression was significantly associated with tobacco and alcohol consumption, and was more frequent in pN0 tumors, early I-II stages. These data unveil the clinical relevance of NANOG in early stages of OSCC tumorigenesis rather than in advanced neoplastic disease. NANOG expression emerges as an early predictor of oral cancer risk in patients with OPMD.
Effects of Rest Position on Morphology of the Vastus Lateralis and Its Relationship with Lower-Body Strength and Power
Authors: Varanoske Alyssa , Coker Nicholas , Johnson Bri-Ana , Belity Tal , Mangine Gerald , Stout Jeffrey , Fukuda David , Wells Adam
Published: September 2019

Ultrasonography of the lower body typically encompasses supine rest due to fluid shifts affecting tissue size and composition. However, vastus lateralis (VL) examination is completed in the lateral recumbent position, and this positional change may influence morphology and its ability to predict function. This study aimed to examine the effect of position on VL morphology and its relationship with lower-body performance. Cross-sectional area (CSA), muscle thickness (MT), pennation angle (PA), echo intensity (UnCorEI), subcutaneous adipose tissue thickness (SFT), and echo intensity corrected for SFT (CorEI) were assessed in 31 resistance-trained males (23.0 ± 2.1 yrs; 1.79 ± 0.08 m; 87.4 ± 11.7 kg) immediately after transitioning from standing to supine (IP), after 15 min of standing (ST), and after 15 min of rest in three recumbent positions: supine (SUP), dominant lateral recumbent (DLR), non-dominant lateral recumbent (NDLR). Participants also completed unilateral vertical jumps, isometric/isokinetic tests, and a one-repetition maximum leg press. CSA, MT, PA, and SFT were greater in ST compared to NDLR, DLR, and SUP (p < 0.05). CSA, UnCorEI, and CorEI were different between recumbent positions; however no differences were observed for MT, PA, and SFT. Different magnitudes of relationships were observed between muscle morphological characteristics measured after rest in different positions and performance variables. Muscle morphology in IP generally appears to be the best predictor of performance for most variables, although utilizing the NDLR and DLR positions may provide comparable results, whereas morphology measured in ST and SUP provide weaker relationships with physical performance. IP also requires less time and fewer requirements on the technician and subject, thus researchers should consider this positioning for VL examination.
The Relation of Tests of Scientific Reasoning to Each Other and to Tests of General Intelligence
Authors: Sternberg Robert J. , Wong Chak Haang , Sternberg Karin
Published: August 2019

We conducted two studies to replicate and extend, as well as test, the limits of previous findings regarding an apparent disconnect between scientific-reasoning skills in psychological science, on the one hand, and scores on standardized tests of general intelligence, on the other. In Study 1, we examined whether this disconnect would extend beyond psychological science to additional sciences as well, such as nutrition and agriculture. The results did indeed extend, suggesting that scientific reasoning across various natural sciences is comparable to scientific reasoning in psychological science, but different in kind from the reasoning required on conventional standardized tests. In Study 2, we examined whether these findings were linked to the format of presentation of scientific problems. Whereas real scientific-reasoning problems are open-ended, standardized tests tend to use multiple-choice format. We discovered that using multiple-choice format did indeed result in an apparently closer relation of the scientific-reasoning tests to two of the conventional ability measures (SAT Reading and Number Series) but not to two other tests (Letter Sets and SAT Math). Thus, one can increase the correlations of scientific-reasoning tests with at least some standardized ability tests but at the cost of content validity and ecological validity.
Fabrication of Piezoelectric Composites Using High-Temperature Dielectrophoresis
Authors: Khaliq Jibran , Hoeks Theo , Groen Pim
Published: September 2019

In this paper, we present a method to create a highly sensitive piezoelectric quasi 1–3 composite using a thermoplastic material filled with a piezoelectric powder. An up-scalable high-temperature dielectrophoresis (DEP) process is used to manufacture the quasi 1–3 piezoelectric polymer-ceramic composites. For this work, thermoplastic cyclic butylene terephthalate (CBT) is used as a polymer matrix and PZT (lead zirconium titanate) ceramic powder is chosen as the piezoelectric active filler material. At high temperatures, the polymer is melted to provide a liquid medium to align the piezoelectric particles using the DEP process inside the molten matrix. The resulting distribution of aligned particles is frozen upon cooling the composite down to room temperature in as little as 10 min. A maximum piezoelectric voltage sensitivity (g33) value of 54 ± 4 mV·m/N is reported for the composite with 10 vol% PZT, which is twice the value calculated for PZT based ceramics.
Friction and Tribo-Chemical Behavior of SPD-Processed CNT-Reinforced Composites
Authors: Aristizabal Katherine , Tayrac Alexandra , Katzensteiner Andreas , Bachmaier Andrea , Suarez Sebastian
Published: August 2019

Nickel (Ni) and carbon nanotube (CNT)-reinforced Ni-matrix composites were manufactured by solid state processing and severely deformed by high-pressure torsion (HPT). Micro-tribological testing was performed by reciprocating sliding and the frictional behavior was investigated. Tribo-chemical and microstructural changes were investigated using energy dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM) and focused ion beam (FIB). The CNT lubricity was hindered due to the continuous formation of a stable oxide layer promoted by a large grain boundary area and by irreversible damage introduced to the reinforcement during HPT, which controlled the frictional behavior of the studied samples. The presence of CNT reduced, to some extent, the tribo-oxidation activity on the contact zone and reduced the wear by significant hardening and stabilization of the microstructure.
Duality Results in Quasiinvex Variational Control Problems with Curvilinear Integral Functionals
Authors: Cipu Elena-Corina
Published: September 2019

In this paper, we formulate and prove weak, strong and converse duality results in variational control problems involving ( ρ , b ) -quasiinvex path-independent curvilinear integral cost functionals.
Geographical Variance in the Use of Tranexamic Acid for Major Trauma Patients
Authors: Walsh Kieran , O’Keeffe Francis , Mitra Biswadev
Published: September 2019

Background and Objectives: The CRASH-2 trial is the largest randomised control trial examining tranexamic acid (TXA) for injured patients. Since its publication, debate has arisen around whether results could be applied to mature trauma systems in developed nations, with global opinion divided. The aim of this study was to determine if, among trauma patients in or at significant risk of major haemorrhages, there is an association of geographic region with the proportion of patients that received tranexamic acid. Materials and Methods: We conducted a systematic review of the literature. Potentially eligible papers were first screened via title and abstract screening. A full copy of the remaining papers was then obtained and screened for final inclusion. The Newcastle–Ottawa Scale for non-randomised control trials was used for quality assessment of the final studies included. A meta-analysis was conducted using a random-effects model, reporting variation in use sub-grouped by geographical location. Results: There were 727 papers identified through database searching and 23 manuscripts met the criteria for final inclusion in this review. There was a statistically significant variation in the use of TXA for included patients. Europe and Oceania had higher usage rates of TXA compared to other continents. Use of TXA in Asia and Africa was significantly less than other continents and varied use was observed in North America. Conclusions: A large geographical variance in the use of TXA for trauma patients in or at significant risk of major haemorrhage currently exists. The populations in Asia and Africa, where the results of CRASH-2 could be most readily generalised to, reported low rates of use. The reason why remains unclear and further research is required to standardise the use of TXA for trauma resuscitation.
Investigation on the Quench Sensitivity of 7085 Aluminum Alloy with Different Contents of Main Alloying Elements
Authors: Li Chengbo , Chen Dongdong
Published: September 2019

The quench sensitivity of 7085 aluminum alloy with different contents of the main alloying elements (Zn, Mg and Cu) was investigated using time-temperature-transformation (TTT) curves and end quenching experiments. Then, the quenching microstructure was analyzed using transmission electron microscopy. With increasing the contents of the main alloying elements, the transitions and nose temperatures of the TTT curves are obviously increased, while the incubation time of 0.5% η (MgZn2) phase precipitation content is decreased. In addition, as the contents of the main alloying elements decrease, the conductivity of the quenched samples is increased, but the hardness of the quenched samples is decreased. Moreover, the size and area fraction of the η phase are increased with increasing the contents of the main alloying elements. Based on the experimental results, the increase of Mg and Cu contents can decrease the stability of supersaturated solid solution and increase the lattice distortion energy, which can increase the quench sensitivity of 7085 aluminum alloy.
Simulation of Thermal Stress and Fatigue Life Prediction of High Speed Steel Work Roll during Hot Rolling Considering the Initial Residual Stress
Authors: Hu Kejun , Zhu Fuxian , Chen Jufang , Noda Nao-Aki , Han Wenqin , Sano Yoshikazu
Published: September 2019

Considerable residual stress is produced during heat treatment. Compressive residual stress at the shell is conductive to improving the thermal fatigue life of a work roll, while tensile stress in the core could cause thermal breakage. In hot rolling, thermal stress occurs under the heating-cooling cycles over the roll surface due to the contact with the hot strip and water spray cooling. The combination of thermal stress and residual stress remarkably influences the life of a work roll. In this paper, finite element method (FEM) simulation of hot rolling is performed by treating the residual stress as the initial stress. Afterwards, the effects of the initial roll temperature and cooling conditions on thermal stress considering the initial residual stress are discussed. Lastly, the thermal fatigue life of a work roll is estimated based on the strain life model. The higher initial roll temperature causes a higher temperature but a lower compressive thermal stress at the roll surface. The surface temperature and compressive stress increase significantly in the insufficient cooling conditions, as well as the center tensile stress. The calculation of the fatigue life of a work roll based on the universal slopes model according to the 10% rule and 20% rule is reasonable compared with experimental results.
A Study on the Failure of AISI 304 Stainless Steel Tubes in a Gas Heater Unit
Authors: Bahrami Abbas , Taheri Peyman
Published: September 2019

This paper investigates a failure in convection section tubes of a gas heater unit in a petrochemical plant. Tubes are made of AISI 304 stainless steel. The failure is reported after 5 years of service at working temperature 500 °C. The failure is in the form of circumferential cracks in the vicinity of the weld. Various characterization techniques, including optical and electron microscopes as well as energy-dispersive X-ray spectroscopy (EDS), were used to study the failure. Results showed that that the damage has initiated in the heat affected zone (HAZ) area parallel to the weld/base metal interface. Cracks have propagated alongside grain boundaries, resulting in an intergranular fracture. The main cause of failure was concluded to be attributable to the grain boundary sensitization and intergranular grain boundary attack due to improper welding and long time exposure of tubes to high temperature. Possible mitigation strategies to minimize similar failures will be discussed.
Label-Free Electrochemical Detection of S. mutans Exploiting Commercially Fabricated Printed Circuit Board Sensing Electrodes
Authors: Dutta Gorachand , Jallow Abdoulie A. , Paul Debjani , Moschou Despina
Published: August 2019

This paper reports for the first time printed-circuit-board (PCB)-based label-free electrochemical detection of bacteria. The demonstrated immunosensor was implemented on a PCB sensing platform which was designed and fabricated in a standard PCB manufacturing facility. Bacteria were directly captured on the PCB sensing surface using a specific, pre-immobilized antibody. Electrochemical impedance spectra (EIS) were recorded and used to extract the charge transfer resistance (Rct) value for the different bacteria concentrations under investigation. As a proof-of-concept, Streptococcus mutans (S. mutans) bacteria were quantified in a phosphate buffered saline (PBS) buffer, achieving a limit of detection of 103 CFU/mL. Therefore, the proposed biosensor is an attractive candidate for the development of a simple and robust point-of-care diagnostic platform for bacteria identification, exhibiting good sensitivity, high selectivity, and excellent reproducibility.
Bio-Precipitation of Calcium and Magnesium Ions through Extracellular and Intracellular Process Induced by Bacillus Licheniformis SRB2
Authors: Zhao Yanyang , Yan Huaxiao , Zhou Jingxuan , Tucker Maurice , Han Mei , Zhao Hui , Mao Guangzhou , Zhao Yifan , Han Zuozhen
Published: August 2019

Removal of calcium and magnesium ions through biomineralization induced by bacteria has been proven to be an effective and environmentally friendly method to improve water quality, but the process and mechanism are far from fully understood. In this study, a newly isolated probiotic Bacillus licheniformis SRB2 (GenBank: KM884945.1) was used to induce the bio-precipitation of calcium and magnesium at various Mg/Ca molar ratios (0, 6, 8, 10, and 12) in medium with 30 g L−1 sodium chloride. Due to the increasing pH and HCO3− and CO32− concentrations caused by NH3 and carbonic anhydrase, about 98% Ca2+ and 50% Mg2+ were precipitated in 12 days. The pathways of bio-precipitation include extracellular and intracellular processes. Biominerals with more negative δ13C values (−16‰ to −18‰) were formed including calcite, vaterite, monohydrocalcite, and nesquehonite with preferred orientation. The nucleation on extracellular polymeric substances was controlled by the negatively charged amino acids and organic functional groups. The intracellular amorphous inclusions containing calcium and magnesium also contributed to the bio-precipitation. This study reveals the process and mechanism of microbial desalination for the removal of calcium and magnesium, and provides some references to explain the formation of the nesquehonite and other carbonate minerals in a natural and ancient earth surface environment.
The Chemistry behind Chocolate Production
Authors: Barišić Veronika , Kopjar Mirela , Jozinović Antun , Flanjak Ivana , Ačkar Đurđica , Miličević Borislav , Šubarić Drago , Jokić Stela , Babić Jurislav
Published: August 2019

Chocolate production is a complex process during which numerous chemical reactions occur. The most important processes, involving most of the reactions important for development of the proper chocolate flavor, are fermentation, drying and roasting of cocoa bean, and chocolate conching. During fermentation, formation of important precursors occurs, which are essential for further chemical reactions in the following processes of chocolate production. Roasting is one of the most important processes due to the occurrence of Maillard’s reactions, during which aroma compounds are formed. In this paper, we have reviewed the most important chemical reactions that occur with proteins, carbohydrates, lipids, and polyphenols. Additionally, we present other components that may be naturally present or form during the production process, such as methylxanthines, aldehydes, esters, ketones, pyrazines, acids, and alcohols.
Does Oxygen Feature Chalcogen Bonding?
Authors: Varadwaj Pradeep R.
Published: August 2019

Using the second-order Møller–Plesset perturbation theory (MP2), together with Dunning’s all-electron correlation consistent basis set aug-cc-pVTZ, we show that the covalently bound oxygen atom present in a series of 21 prototypical monomer molecules examined does conceive a positive (or a negative) σ-hole. A σ-hole, in general, is an electron density-deficient region on a bound atom M along the outer extension of the R–M covalent bond, where R is the reminder part of the molecule, and M is the main group atom covalently bonded to R. We have also examined some exemplar 1:1 binary complexes that are formed between five randomly chosen monomers of the above series and the nitrogen- and oxygen-containing Lewis bases in N2, PN, NH3, and OH2. We show that the O-centered positive σ-hole in the selected monomers has the ability to form the chalcogen bonding interaction, and this is when the σ-hole on O is placed in the close proximity of the negative site in the partner molecule. Although the interaction energy and the various other 12 characteristics revealed from this study indicate the presence of any weakly bound interaction between the monomers in the six complexes, our result is strongly inconsistent with the general view that oxygen does not form a chalcogen-bonded interaction.
Diminished Prolinemia in Chronic Chagasic Patients: A New Clue for Disease Pathology?
Authors: Rocha Sandra Carla , Pérez Ana Rosa , Beloscar Juan , Bottasso Oscar , Silber Ariel Mariano
Published: August 2019

Trypanosoma cruzi, the etiological agent of Chagas disease, is dependent on proline for a variety of processes, such as energy metabolism, host cell invasion, differentiation, and resistance to osmotic, metabolic, and oxidative stress. On this basis, we investigated a possible relationship between prolinemia and severity of T. cruzi infection in chronic patients, as reported here. The study population consisted of 112 subjects, separated into 83 chronically T. cruzi-infected patients and 29 age-matched healthy volunteers (control) of both sexes, recruited at the Chagas Disease Service from the Department of Cardiology, Hospital Provincial del Centenario de Rosario (Rosario, Argentina). Chagasic patients were separated into three groups: chronic asymptomatic, mild/moderate, and severe chronic chagasic cardiomyopathy (CCC) subjects. We observed a significant decrease of 11.7% in prolinemia in chagasic patients when compared to controls. Further analysis within the three groups of chagasic patients also revealed a statistically significant decrease of prolinemia in severe CCC patients compared to controls, showing a relative difference of 13.6% in proline concentrations. These data point to the possibility that collagen—which participates in the healing process of cardiac tissue—and proline metabolism in the myocardium could constitute new factors affecting the evolution of Chagas disease.