bluuebunny/crossref_metadata_2025 huggingface dataset:
Umbilical cord length and cord abnormalities in term singleton pregnancy: A Review of pregnancy outcome in a tertiary health institution in Nigeria
Authors: Njoku Charles Obinna , Odusolu Patience , Cajetan Emechebe , Ekanem Emmanuel , Njoku Amarachukwu
Published: March 2022

Objective: To determine the association of feto-maternal  outcomes  of term pregnancies with  fetal umbilical cord lengths and cord abnormalities in Calabar.

Methods:  A cross-sectional study of 600 women with singleton pregnancies who delivered either virginally or caesarean section between 37 and 42 completed weeks. Examination of cord was done at delivery for loop round neck, cord length, knots and cord abnormalities. Outcomes recorded include foetal presentation, sex,  birth weight, length of newborn and Apgar scores at 1st and 5th minutes. Also, mode of delivery, labour duration and maternal complications were noted.  Cords with abnormalities were sent for histological examination. Data was analyzed using SPSS version 20. Level of significance was set at p-value < 0.05.

Results:  The mean cord length was 61.07 Â± 14.931cm, short  cords were 23(7.7%), long cords were 37 (12.3%) and 480 (80.0%) were normal length.  Male foetuses had longer cords,   mean cord length in the vertex presentations were significantly longer than in breech presentation and increased with increase in birth weight.  Abruptio placenta was higher among foetuses with short umbilical cord.  (17.4% vs 0.4%) (p-value-0.000).   There was positive correlation between foetal weight and umbilical cord length. Cord coiling index showed a negative correlation with cord length (r = -0.261; p-value = 0.000).

Conclusion: Abnormal umbilical cord lengths significantly predispose to obstetric complications but cord abnormalities are rare and does not affect pregnancy outcome.  High index of suspicion and careful evaluation of cord may inform and reduce untoward feto-maternal outcome
Immunohistochemical Expression of SIRT1 in Oral Squamous Cell Carcinoma and its Relationship with Clinical-Pathological Factors
Authors: Seyedmajidi Maryam , Nafarzadeh Shima , Rayani Arezoo , Moslemi Dariush , Bijani Ali , Sharbatdaran Majid
Published: March 2022

Objective: Oral squamous cell carcinoma (OSCC) is the most common oral cancer in the world that threatens public health. There are a number of molecular markers that can be used to improve TNM staging. One of these markers is SIRT1. We aimed to investigate the expression of SIRT1 in OSCC and its relationship with clinicopathological factors such as age, sex, location of tumor, smoking, clinical stage, grade of tumor, metastasis to lymph nodes in the neck and distant metastasis.

Methods: This cross-sectional study was performed on 30 samples of OSCC and 30 samples of normal oral mucosa. Required clinical data were collected from patients. After immunohistochemistry staining for SIRT1 on sections prepared with paraffin blocks, the percentage of stained cells and staining intensity of the cells were evaluated in the terms of core and cytoplasmic aspects.

Results: Positive expression of SIRT1 was seen in 93.3% and 96.7% of cells in the core and cytoplasm view, respectively, which was significantly higher than normal tissue (P=0.021 and 0.001, respectively). We found no significant relationship between the intensity and percentage of core and cytoplasmic staining of squamous cells as well as clinicopathological factors.

Conclusion: The overexpression of SIRT1 in OSCC samples as compared with normal mouth tissue indicates its role in carcinogenesis. However, further studies on SIRT1 may shed more light on the treatment options of OSCC.
Application of PLGA-ion exchange resin microcapsules of sulfasalazine â€Žfor embolization therapy
Authors: Wohaib Ameer Zuhair , Maraie Nidhal K. , Jassim Gaith A.
Published: March 2022

ABSTRACT

Objective: This work involves preparation and evaluation (in vitro/ in vivo) of microcapsules containing sulfasalazine- ion exchange resin complex (resinate) to induce emboli for treatment of solid cancer.

Methods: The drug resin complex (resinate) had been optimized by using drug: resin ratio (1:8), by suspending the resin in sulfasalazine aqueous solution with at 400 rpm for 120 minutes at 50 ÂºC. For controlling the release of drug, microencapsulation for the resinate was applied where 21 formulas with different resinate: PLGA ratios 2:1, 1:1, 1:2 were prepared by solvent evaporation method to study the effect of different variables including resinate: polymer ratio, stirring speed, effect of temperature and aqueous phase volume on microencapsulation efficiency and percent yield.

Results: The in-vitro release study for the prepared resinate, which had 72% entrapment efficiency, showed 80.992 % of drug released within 15 minutes and the release continued until 99.83% within 75 minutes formula was found to be F19 had 76.70% encapsulation efficiency and 89.40% percent yield. The in vitro release study for selected formula showed that 32% of drug released within 1hour and 78% of drug released within 20 days and the release continued up to 96% within 45 days indicating a controlled release manner with spherical microcapsule of 595Âµm. The preliminary in vivo work using rabbits showed instant occlusion of the central auricular artery of the rabbit ear leading to ischemia within 3 days that continued to the end of study period

Conclusion: This work show the suitability of microcapsules size to prevent blood flow and forming embolization with controlling release of the drug that may treat the solid tumor.
Teratogenic effect of the aqueous extract of the Foeniculum vulgare (fennel) on fetal development in mice
Authors: Shayan Maryam , Mehrannia Kobra , Rastegar Tayebeh , Khanehzad Maryam , Ghantabpour Taha , Hassanzadeh Gholamreza
Published: March 2022

Objective The present study evaluated the effect of aqueous extract of Foeniculum vulgare on fetal development in pregnant mice models.

Methods A total number of 24 female BALB/c mice with a weight range of 25-30 gr divided into four groups. Each group received 0.25 ml of the aqueous extract of Foeniculum vulgare with different concentrations (2.5 mg, 12.5 mg, 25 mg) and distilled water as a control group. The aqueous extract of Foeniculum vulgare administered via oral gavage on a daily basis from day 6 to day 15 of pregnancy. On day 16, the fetuses were analyzed in terms of morphological changes, skeletal disorders, and cellular alterations.

Results The result showed the dose-dependent teratogenic effect of the aqueous extract of Foeniculum vulgare. At 12.5 mg and 25 mg concentration, the teratogenic effect was more severe. Oral gavage administration of the aqueous extract of Foeniculum vulgare increased the number of dead fetuses and reduced the average weight, height, and crown-rump length. Subcutaneous hemorrhage, dorsal lesion, wrinkled skin, and considerably lower than normal fetal weight observed in gross morphological inspection at 25 mg concentration. The skeletal studies revealed fetal anomalies, reduction in ossification and reduction in the number of ribs. Internal bleeding around the liver and lungs, pulmonary fibrosis and disruption in the arrangement of hepatocytes was also observed in histological analysis.

Conclusion Administration of the aqueous extract of Foeniculum vulgare results in embryotoxicity in mice models in morphological, skeletal and cellular levels.

Keywords Foeniculum vulgare, Fennel, Teratogenicity, Embryotoxicity, Fetal Development, Mice
Ferritin level may be a major factor in young females with recurrent aphthous stomatitis
Authors: Dar-Odeh Najla , Abu-Hamamd Osama
Published: March 2022

Recurrent aphthous stomatitis is considered the most common type of recurrent oral ulcers that affects adversely the quality of life of patients. Its etiology is not well understood, however, nutritional and psychosocial factors have been suggested in a certain category of patients. The aim of this case series is to describe the hematological picture namely hemoglobin level, serum vitamin B12 and serum ferritin in six young female patients affected by recurrent aphthous stomatitis, and to report its association of low serum ferritin.
Premalignant changes associated chronic gastritis in Karbala Province: multi institutional study
Authors: AlSafi Rasha Abd Alraouf Neama , Alqanbar Mohammed F. , Al-Sabbagh Wafaa Redha Mohammed
Published: March 2022

Objectives: The aim of this study was to investigate the prevalence of gastric premalignant changes as gastric atrophy, intestinal metaplasia and dysplastic changes in patients underwent esophagogastroduodenoscopy in three health institutions in Karbala province.

Methods: The data was collected from patients attended the endoscopy units during a period from January  to September 2018 in three medical centers in holy Karbala/ Iraq, Al Hussein teaching hospital, Imam Zain Al Abedin hospital and Imam AL Hujjah hospital. It includes 215 males and 285  females who were subjected to esophagogastroduodenoscopy (EGD) from whom mucosal biopsies were taken. These biopsies were stained by Giemsa to detect H. pylori organisms.

Results: The mean age of patients was (40.9 +/- 15 years SD). H. Pylori infection was demonstrated in (71%) patients, (19.4%) were presented with glandular atrophy, (7.4%) out of 500 patients had intestinal metaplasia and only 6 (1.2%) patients had dysplastic changes. there was a significant statistical relation between gastric glandular atrophy and age, p value (0.03). there was a significant statistical relation between glandular atrophy and infection with H. Pylori, p value (0.001). there was a significant negative relation between H. Pylori infection and the existence of intestinal metaplasia, p value (0.0001). this study show a significant statistical relationship between the existence of intestinal metaplasia and the occurrence of  dysplastic changes, P value (0.001).

 Conclusion: the current study show a significant relation between aging and the existence of gastric glandular atrophy. There was a significant relation between each of gastric glandular atrophy and intestinal metaplastic changes with the H. pylori infection. there was a significant relation between gastric intestinal metaplasia and dysplastic changes.
Accuracy of Linear Measurements Made on Cone Beam Computed Tomography Scans at Different Magnifications
Authors: Ghaznavi Aisan , Ghaznavi Dara , Valizadeh Solmaz , Vasegh Zahra , Al-Shuhayeb Muna
Published: March 2022

Objective: This study aimed to evaluate the accuracy of linear measurements made on CBCT (New Tom VGi) scans with different image magnifications.

Methods: Forty-two titanium pins were inserted into seven dry sheep mandibles. Lengths of the pins were measured using a digital caliper with 0.01 mm readability, and the mandibles were radiographed using a CBCT unit. After reconstruction of CBCT images, three experienced radiologists measured the length and diameter of titanium pins at100%, 200% and 400% magnifications. Accuracy of measurements was analyzed using descriptive statistics and one-way analysis of variance (ANOVA) P<0.05 was considered statistically significant. Inter observer reliability was calculated using the intra class correlation coefficient (ICC) test.

Results: The mean differences of linear measurements from the actual lengths of pins were 0.1960 mm, 0.2143 mm and 0.2047 mm at 100%, 200% and 400% magnifications, respectively (P>0.05). The mean differences of linear measurements from the actual diameters of pins were 0.2206 mm, 0.2063 mm and 0.1984 mm at 100%, 200% and 400% magnifications, respectively (P>0.05). Inter observer reliability of pin length measurements was estimated to be0.285, 0.707 and 0.479 at 100%, 200% and 400%magnifications, respectively. Inter observer reliability of pin diameter measurements was 0 .078, 0.469 and 0.587 at 100%, 200% and 400%magnifications, respectively.

Conclusion: Based on the results, image magnification does not affect the accuracy of linear measurements made on CBCT scans. Inter observer reliability of pin length measurements was good at 200% magnification, while it was below the acceptable range at other magnifications. For measurement of pin diameters, this index was below the acceptable range at all magnifications.
The development of halal food industry in Bangka Belitung Island: an analytic network process
Authors: Suhel Suhel , Mukhlis Mukhlis , Bashir Abdul , Fitriyanti Eka
Published: March 2022

This study analyzes the development of the halal food industry in Bangka Belitung Island. Development is measured by innovation strategy, product strategy, promotion strategy, pricing strategy, and collusion strategy. The data used are primary data obtained from in-depth interviews with five experts and practitioners with competent considerations in the field of the halal food industry—the analysis technique applying the Analytic Network Process. The findings indicated that the most superior aspects in the behavioral cluster are innovation strategy, product strategy, promotion strategy, price strategy, and collusion strategy. Meanwhile, the result from the benefit, cost, opportunity, risk (BOCR) cluster, the order of aspects that best describes the condition of the halal food industry in Bangka Belitung, is an opportunity, benefit, cost, risk. It is hoped that there will be a joint commitment from policy-makers in supporting and encouraging efforts to develop the halal food industry in Indonesia. It is expected that industry agents can further optimize industrial behavior, especially promotion and collaboration strategies.
Trends of organizational branding strategies- systematic review and research agendas
Authors: Alemu Debebe , Zewdie Shimelis
Published: March 2022

Branding is among the activities that seek new ways to balance competition in the business environment to sustain organizational competitive advantage. Hence, this study aims to identify how the concept has been considered in the literature and its evolution in the marketing literature. To achieve the objectives of the systematic study review was conducted from 2010 to 2021 years and identified 98 articles. The collected data were documented in Microsoft Word and retained in Mendeley referencing software. The study revealed that brand and product management lacks conceptual clarity, which influences their measurement and subsequently their management. The review also demonstrates as economic, identity, consumer-based, personality, relational, community, cultural, and sensory approaches, respectively, are the respective evolutions of the concepts.
Moderating effect of social capital on community empowerment and economic well-being
Authors: Sarjiyanto Sarjiyanto
Published: March 2022

Improving community economic well-being based on community empowerment plays an important role in rural development. This study aims to determine the ability of social enterprises in Indonesia (Village-Owned Enterprises/BUMDes) to improve the community's economic well-being through empowerment programs and the role of social capital in rural community development. At social conditions at the basic level, very little attention is paid to the development of deprived communities. Starting from the experience of rural community economic empowerment programs through the establishment of Village-Owned Enterprises (BUMDes) in Indonesia, this study will test three hypotheses: (1) whether there is an effect between community empowerment and the economic well-being of rural communities; (2) is there an effect between social capital and the economic well-being of rural communities; and (3) is the effect between community empowerment and economic well-being mediated by social capital? Multiple regression analysis is used to examine the effect between community empowerment and community economic well-being. This analysis highlights the central role of social capital in mediating the effect between community empowerment and economic well-being. Community empowerment is significantly related to social capital. These effects between social capital, community empowerment, and economic well-being apply to theories and measures of rural community empowerment.
The role of digital technology in people-centered development: the basic needs approach in the Kampung Marketer Program
Authors: Sulasih Sulasih , Suroso Agus , Novandari Weni , Suliyanto Suliyanto
Published: March 2022

The Kampung Marketer program is a youth empowerment program specializing in digital marketing. The basic needs approach is used to evaluate community development. This approach states that it is necessary to have greater job opportunities, increase economic growth, and guarantee the community's basic needs for a better quality of life. This research aims to determine how digital roles are implemented in people-centered development and measure its impact with the basic needs approach. A qualitative approach uses a triangulation model that combines in-depth interviews, observations, and documents from Kampung Marketers. From the research results, it was found that digital resources aided people-centered development by increasing employment opportunities. In the 18 existing branches, the Kampung Marketer Program has accumulated 700 customer service and advertising skills. As a result of the program, the economic growth of communities with Kampung Marketer programs had increased, as indicated by the amount of income received by the empowered community of around IDR 1,000,000 to IDR 3,000,000 and the total income that was distributed being 1.3 billion. It impacts meeting the basic needs of society and increasing the younger generation's enthusiasm for continuing their studies. The members of Kampung Marketer also could now pay for their children's tuition and even bought houses and land. The older generation who did not have technological skills were also supported and empowered by the program by establishing a business called "Saung Makaryo." They were trained to produce goods in their respective homes, and Kampung Marketers marketed them.
Studi Laju Infiltrasi Pada Lahan Irigasi Gumbasa (Studi Kasus di BGKn 38, 42 dan 51)
Authors: Afrianto B. , Sutapa I.W. , Hidayat N. , Herman R.
Published: March 2022

The 2018 earthquake that shook the city of Palu and surrounding areas with the power of 7.4 MW triggered liquefaction in several locations. Earthquakes and liquefaction that occurred caused damage to Gumbasa’s irrigation canals and some paddy fields. This study was conducted at three points in the paddy fields which 2 points located in the Soulowe village and Sidera village, District of Dolo and one is located in the Lolu village, District of Biromaru. This study aims to determine the infiltration rate in the residents’s paddy fields which have not been planted with paddy for a long time. This is because until the data retrieval performed, Gumbasa irrigation network has not functioned and still under repair. Data were collected using a Double Ring Infiltrometer measuring instrument. The results obtained from this study for constant infiltration rate of BGKn 38 = 1.27 cm/hour, BGKn 42 = 1.10 cm/hour and BGKn 51  = 0.75 cm/hour, which all three are classified as a rather slow with a constant infiltration rate ranging from 0.5 to 2 cm/hour. For the difference in fc values, BGKn 38 and BGKn 42 at 0.17 cm/hour and BGKn 42 and BGKn 51 at 0.35 cm/hour, so that BGKn 38 and BGKn 51 is 0.52 cm/hour. Meanwhile, the value of the difference f0 from the three points is BGKn 38 with BGKn 42 at 3.82 cm/hour and BGKn 42 with BGKn 51 at 4.43 cm/hour, and BGKn 38 with BGKn 51 is 0.61 cm/hour.
Tinjauan Kinerja Simpang Empat Bersinyal Menggunakan Program KAJI dan SIDRA (Studi Kasus: Simpang Pasar Moodu, Gorontalo)
Authors: Arsyad A.W. , Kadir Y. , Desei F.L.
Published: March 2022

The Moodu Market intersection is a signalized intersection formed by the convergence of Jalan Sultan Botutihe-Jalan Matolodula and Jalan Prof Dr. H. Aloei Saboe. This intersection is one of the accesses to the Aloei Saboe Hospital, Fourth Campus of the State University of Gorontalo, offices in Bone Bolango Regency, and close to Moodu market. Large traffic flows that pass through this intersection causes congestion. The purpose of this research was to analyze the permormance of the intersection to determine the level of service at the intersection. The analytical method used to determine the performance of the intersection was conducted using the KAJI and SIDRA programs. Observations were conducted in three days (Monday, 22 March 2021; Thursday, 25 March 2021; and Sunday, 28 March 2021) starting att 06.00-18.00 WITA. The data used in the analysis included the intersection’s geometry, signal time, traffic volume, side barrier, cruise speed, pedestrian, and the population of Gorontalo City. The data was processed to find the values used to determine the performance of the intersection. Based on the results of analysis using the KAJI program, the average delay was 16.73 seconds for the north approach (Jalan Prof. Dr. H. Aloei Saboe), 12.75 seconds for the south approach (Jalan Matolodula), 25.86 seconds for the east approach (Jalan Sultan Botutihe), and 52.67 secinds for the west approach (Jalan Sultan Botutihe). Meanwhile, the results of the analysis using the SIDRA program showed that the average delay was 64.4 seconds for the north approach (Jalan Prof. Dr. H. Aloei Saboe), 13.1 seconds for the south approach (Jalan Matolodula), 42.0 seconds for the east approach (Jalan Sultan Botutihe), and 13.3 seconds the west approach (Jalan Sultan Botutihe). The average delay of the intersection based on the KAJI program was 32.11 seconds where its Level of Service was D while the average delay of the intersection based on the SIDRA program was 36.8 secinds whereas its Level of Service was D. The average percentage difference in the intersection delay using the KAJI and SIDRA Program was 12.75%.
Kajian Pola Aliran di Hilir Pintu Sorong dengan Material Dasar Saluran Pasir Lempung
Authors: Rustiati N.B. , Suciani N.
Published: March 2022

The operation of a damaged (jammed) sluice result unsuitable velocity distribution with the design. This causes turbulence of the flow which results the hydraulic jump. The hydraulic jumps as a function of energy absorbers. The large energy will cause damage to the water structure. Therefore, there is a need for research to obtain flow profiles. The aims of the research is to investigate the flow characteristic and hydraulics jump that occurred at downstream of manually moving of sluice gate. The height of opening gate set up variated at 0.4 cm to 1.4 cm. The range of using variated discharge from 0.108 lt/s to 0.524 lt/s. The result of investigation showed that the higher of opening gate at the same discharge value the hydraulics characteristic at the downstream of sluice gate decreasing. The hydraulics characteristic are the water depth, hydraulics jump and the flow characteristic. As a results variation discharge and opening gate are subcritical flow.
Kinerja Portal Struktur Gedung Tahan Gempa dengan Sistem Ganda Menggunakan Metode Pushover Analysis
Authors: Septian N. , Turuallo G. , Sulendra I.K.
Published: March 2022

Buildings damages due to earthquakes generally happen because designs of the buildings do not consider earthquake resistance aspects and do not fulfil the technical standards of earthquake resistant buildings. The structure designed in this work was a seven-storey office building, with a symmetrical design plan. The earthquake-resisting system used was dual system with special moment resisting frame (SMRF) and special shear wall for reinforced concrete. The materials used in this design were concrete with compressive strength of f 'c = 30 MPa, Plain Steel Bars Grade 24 (fy = 235 MPa), and Deformed Steel Bars Grade 40 (fy = 390 MPa). The calculation structural elements results gave: the size of main beams of 40 x 60 cm2, with reinforcement varying from 4D22 to 12D22 in the support area and from 3D22 to 5D22 in the midspan area; secondary beams with the size of 25 x 40 cm2, with reinforcement of 2D22 both in the support area and midspan area; the size of columns were 95 x 95 cm2, with reinforcement varying from 20D25 to 28D25; a 30 cm thick of shear walls reinforced with 2D22-175 mm (in x-axis) and 2D22-125 mm (in y-axis); 12 cm thick slabs reinforced with Ø12-200 mm . For the tie beams with the size of 40 x 55 cm2, had reinforcement varying from 2D22 to 4D22 in the support area and from 3D22 to 5D22 in the midspan area. Pushover analysis results in a maximum total drift  of 0,00425 which means the performance level of the structure is Immediate Occupancy
Analisis Perpindahan Besar Akibat Gaya Non-Konservatif
Authors: Dolu A. , Nasution A. , Rivani A. , Oka G.M.
Published: March 2022

Structural applications based on large displacement analysis are widespread in various fields, such as the application of aircraft structures, membranes, cables, pipelines and risers. In this study, the author reviews the structural responses based on large displacement theory and non-conservative load models, assuming linear sections and materials. The parameters reviewed are the variation of the load factor and the variation of the slope angle of the load P at the end of the span. Solving non-linear differential equations with non-conservative force, using numerical integration method. The simulation results with the variation of the load factor with the angle of inclination, vertical and horizontal displacements are obtained, where the final orientation of the acting force corresponds to the deformation of the structure, and the maximum deformation occurs at a load angle of 90o, the deformation decreases for the angle orientation is getting smaller.
Persepsi dan Tingkat Keselamatan Pengguna Sepeda di Kota Palu
Authors: Ridwan N.A. , Ramlan R. , Lestari S.P. , Fadilah I.
Published: March 2022

Since the outbreak of the Covid-19 Pandemic in Indonesia, there has been an increase in public interest in using bicycles, especially when exercising. This study aims to determine the characteristics, behavior, safety, habits, and perceptions of bicycle users in Palu City at this time, then a questionnaire was distributed with a total of 132 participating respondents. The method of descriptive and frequency data analysis shows that the characteristics of cyclists generally cycle in weekend (88,6%) which is to exercise or visit sightseeing spots (78%), cyclist behavior is generally still good in the relationship between road users (98,5%), cyclist safety is indicated by the accident rate of 43,2% which is generally a single traffic accident (91,2%), cyclist generally increases their habit of exercising or visiting the sightseeing spots (10,6%) and visiting friends or family’s houses (5,3%) and the perception of cyclist who generally understands safety requirements when cycling (79,5%) and agrees that cycling can improve environmental quality (90,2%).
Identifikasi Risiko yang Mempengaruhi Pelaksanaan Proyek Konstruksi Jalan di Kota Palu Berdasarkan Persepsi Konsultan
Authors: Fahirah F. , Tlantan J.S.
Published: March 2022

In the implementation of a road construction project in any form and anywhere will never avoid risk, both small risk and big risk. The larger the scale of a construction project, the greater the possibility of risks that will occur if these risks are not managed properly. The purpose of this study was to identify risks that affect the implementation of road construction projects based on the perceptions of the consultants. Primary data was collected through the distribution of questionnaires to consulting companies that have supervised the implementation of road construction. The data was processed using descriptive statistics, Relative Rank Index (RRI) and Correlation Analysis. The results showed that 5 dominant risks were identified that affected the implementation of road construction based on the consultant's perception, namely 1) Using inappropriate work methods would make work late (RRI = 0.896), 2) Wrong Planning Data of DED (Detail Engineering Design)  that resulted in frequent design review (RRI = 0.880), (3) inefficient use of heavy equipment makes work productivity not achieved according to plan (RRI = 0.864), (4) limited field workers resulting in productivity cannot be maximized (RRI = 0.864, (5) maintenance affects the level of damage to heavy equipment (RRI = 0.824). The risk of using an inappropriate work methods would make the work late is strongly correlated with the risk of limited field workers resulting in productivity cannot be maximized, with a correlation value of 0.542.
Studi Eksperimen Penambahan Tailing Pada Campuran Mortar Sebagai Substitusi Parsial Semen Untuk Dinding Panel
Authors: Kurniaty D.R.
Published: March 2022

Poboya is located in East Palu District, Palu City, Central Sulawesi. This village is now an area that has become a traditional gold mining activity. The end result of the mining process in the form of these deposits becomes waste which is commonly referred to as tailing. This waste contains a lot of carbon and no one has utilized it. This study was conducted to determine the optimum percent value of adding tailing to the mortar mixture so that it can affect the compressive strength of the mortar. This research uses experimental methods and literature studies. The location of the research was carried out at the Laboratory of Structures and Building Materials, Faculty of Engineering, Tadulako University. The variations used in the use of gold mine waste (tailing) as partial cement substitution are 50% and 75% by weight of cement. Tailings will replace some of the cement in a mortar mix made of sand, cement and water. The test to be carried out is the compressive strength of the mortar at the age of 7 and 28 days. Mortar test object made measuring 5 x 5 x 5 cm. The results obtained showed that 50% tailings had a higher compressive strength of 156 kg/cm2 than mortar using 75% tailing only had a compressive strength of  21.33 kg/cm2 at the age of the specimen 28 days. Mortar is used for the manufacture of wall panels with ferrocement technology.
Asesmen Bangunan Gedung Pemda Kota Palu, Donggala dan Parigi Moutong Pasca Gempa 28 September 2018
Authors: Listiawaty H. , Sulendra I .K. , Hilmansyah T.
Published: March 2022

After a strong earthquake with a magnitude of 7.4 on the Richter Scale with a hypocenter of 10 km and an epicenter of about 70 km north of Palu City, precisely in Lende Village, Sirenja District, Donggala Regency, it caused damage and collapse of buildings due to vibrations, fractures of down lifts and up lifts around the fault trajectory. Palu-Koro. Damage and failure of high-rise and non-rise buildings occurred in Palu City, Donggala City, and Parigi City. Damage to the building can be categorized as light, moderate or heavy damage, so it is deemed necessary to conduct an assessment according to the applicable requirements both on a national scale (using the Ministry of Public Works and Public Housing's 2010 form) and an international form (using a form from the World Bank). This activity aims to determine the level of damage and post-earthquake handling in the form of minor repairs, reinforcement and repair of structural and non-structural elements. There are 6 (six) main buildings in the 3 (three) areas that have been assessed to determine the category of damage and actions for rehabilitation and reconstruction. Damage to the building structure with the category of Light Damage occurred in the Palu City DPRD Office building, the Donggala Regent and DPRD Office and the Anuntaloko Parigi Hospital Inpatient Building. Those that were moderately damaged were the Palu Mayor's Office building and the Parigi Moutong DPRD office. The damaged buildings still allow for repairs and reinforcement according to the level of damage. The repair and strengthening of buildings in order to get good results must be carried out with the right method, good materials and tools and technology and carried out by experienced workers with high qualifications
Pengaruh Infrastruktur Transportasi Terhadap Gross Domestic Product (GDP) Per Capita Pada Negara-Negara Anggota ASEAN
Authors: Wafa M.I. , Narendra A.
Published: March 2022

The purpose of this study is to model the relationship between Gross Domestic Product (GDP) and transportation infrastructure in ASEAN member countries. In addition, this study also compares the data predicted by the model with actual data in Indonesia. Transportation infrastructure includes air transportation, sea transportation, and land transportation (railway). The data used is secondary data from the World Bank (World Development Indicator) 1960-2019. The analytical method used in this research is Statistical Descriptive Analysis and Multivariate Regression Analysis. The results of this study resulted in a multivariate regression model Y = 6,478 – 7,871(X2) + 4,875(X4) – 2,390(X5) – 2,27(X7) + 5,569(X8). This model produces a p-value of 2.619E-13 <0.05, which means that this model has a significance of 2.619E-13 and produces an R2 of 0.95 which means the variables X2 Air transport, passengers carried, X4 Quality of port infrastructure, X5 Container port traffic, X7 Rail lines, X8 Railways, passengers carried affect the Gross Domestic Product (GDP) per capita by 95% and the other 5% is influenced by other factors. This regression model in predicting actual data for the case of GDP in Indonesia is 120.84%, meaning that this model cannot be used to predict actual data in the case of GDP in Indonesia.
Recurrent erythema annulare centrifugum and tonsillitis
Authors: bouzid sana , Korbi Mouna , ameur khaoula , Belhadjali Hichem , Youssef Monia , Zili Jameleddine
Published: March 2022

Recurrent post-tonsillitis erythema annulare centrifugum is a recently
described entity in two adults with recurrent annular lesions and
centrifugal evolution following tonsillitis. We present two cases of
recurrent post-tonsillitis erythema annulare centrifugum in children.
Lamotrigine-Valproic Acid combination leading to severe skin drug reactions in children
Authors: Chakiri Radia , Nainia Khalila , Khabbal Youssef
Published: March 2022

Drug exposure is the most common cause of severe cutaneous reactions.
Toxic epidermal necrolysis, erythroderma, drug rash with eosinophilia
and systemic symptoms, acute generalized exanthematous pustulosis and
drug induced vasculitis are the common cutaneous drug reactions which
can have severe morbidity and evenmortality. Antiepileptics are among
the drugs incriminated.
CASE REPORT: Coronavirus with acute kidney injury
Authors: Aref Asieh
Published: March 2022

Known case COVID-19 is with the appearance of acute kidney injury with
no previous history. Pathology studies mainly showed histological
findings are consistent with thrombotic microangiopathy. With a high
prevalence of comorbidities such as acute kidney injury, patients could
suffer from severe forms of COVID-19.
Obstetric Hemorrhage Volume and Severe Morbidity: A Retrospective Cohort Study
Authors: Wang Michelle , Alexander Megan , Abbas Diana , Srivastava Akanksha , Comfort Ashley , Iverson Ronald , Cabral Howard , Yarrington Christina
Published: March 2022

OBJECTIVE: Our goal is to describe the association between total
quantitative blood loss (QBL) and risk of obstetric hemorrhage-related
morbidity (OBH-M) in order to assess utility of the current definition
of obstetric hemorrhage (OBH). DESIGN: Retrospective cohort study.
SETTING: Urban safety-net hospital in Boston, Massachusetts. POPULATION
or SAMPLE: Deliveries at our institution over a two-year period.
METHODS: We categorized deliveries into ten equally sized deciles based
on QBL and compared the proportion with OBH-M in each. Among the two
deciles with the highest proportions of OBH-M, we stratified deliveries
into seven groups of ascending intervals of 250cc QBL. Finally, we
compared the positive predictive value (PPV) of the standard definition
of OBH (QBL ≥ 1000cc) to a definition extrapolated from our stratified
analysis. MAIN OUTCOME MEASURES: The primary outcome was proportion of
deliveries within each QBL decile affected by OBH-M. The secondary
outcome was PPV. RESULTS: We found a significant increase in OBH-M from
decile 9 (895-1201cc QBL) to decile 10 (1205-8325cc QBL)
(p<0.001). In our stratified analysis, we found QBL of 1500cc
to be an inflection point for an increased proportion of OBH-M. Our
secondary analysis showed an increased PPV for OBH-M using QBL of 1500cc
(20.5%) compared to that of QBL 1000cc (9.8%). CONCLUSIONS: Our
findings suggest that a higher QBL threshold than the currently accepted
definition of OBH is more predictive of OBH-M.
Partial atrioventricular septal defect with left atrioventricular valve aneurysm mimicking valve perforation
Authors: Lenoir Marien , Ranaivoson Holy , Casalta Anne Claire , Macé Loïc , Aldebert Philippe , THERON Alexis
Published: March 2022

Left atrioventricular valve aneurysm is rare. We present a rare case of
partial atrioventricular septal defect with an extremely thin left
atrioventricular valve aneurysm mimicking valve perforation. The
preoperative echocardiography demonstrated severe left sided
atrioventricular valve regurgitation on the “cleft” and leaflet
perforation. But in per-operative, we discovered a left sided
atrioventricular valve aneurysm instead of valve perforation. The
“cleft” edge and a aneurysm were closed.
Could SARS-CoV-2 Infection Change Fetal Cardiac Output?
Authors: Turgut Ezgi , Sakcak Bedri , HENDEM D.UYAN , Oluklu Deniz , Ayhan Sule Goncu , Sahin Dilek
Published: March 2022

Aim: We aimed to examine fetal cardiac output (CO) in patients who
recovered from severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection. Materials: This prospective study included 48
pregnant women recovered from SARS-CoV-2 infection and 50 control cases.
SARS-CoV-2 infection was diagnosed by polymerase chain reaction (PCR)
test in patients. Fetal echocardiographic evaluations were performed at
24-37 weeks of gestation in pregnant women who recovered from the
infection and control group. Results: The median value of ultrasound
evaluation was 34 (2.6) weeks of gestation in the recovery from the
SARS-CoV-2 infection (RSI) group, and 32 (7.6) weeks in the control
group (p=0.565). Left cardiac output (LCO) z score was significantly
lower in the RSI group than the control group (p=0,041). LCO and combine
cardiac output (CCO) z score were significantly lower in the severe
disease group than mild, moderate disease groups, and controls (p=0,019
and p=0,013). CCO (mL/min/kg) was decreased in the severe disease group
when compared with control and mild disease groups (p=0,044). Fetal
distress, preterm delivery rate, and neonatal intensive care unit (NICU)
admission were found to be higher in the severe disease group compared
to the control group (p=0,010, p=0,009, and p<0,001
respectively). Conclusion: In the present study, fetal cardiac output in
pregnant women with recovery from SARS-CoV-2 infection was found
significantly decreased, especially in whom had severe diseases.
Placental dysfunction and inflammatory cytokines might cause fetal
cardiac changes. Further studies could be clarified on the impact of
SARS-CoV-2 infection on fetal cardiac function.
Case Report of Rescue of COVID-19 Complicated by Pneumothorax and Acute Pulmonary Thromboembolism
Authors: Qu Jiachun , Xu Kui
Published: March 2022

The 2019 novel coronavirus (2019-nCoV) is a respiratory pathogen able to
cause a wide spectrum of disease, transmitted through the air and by
droplet spread when an infected person sneezes or by contact with
contaminated objects.
Human pharmacokinetics of XBD173 and etifoxine distinguish their potential for pharmacodynamic effects mediated by TSPO
Authors: Owen David , Phillips Alexandra , O'Connor Desmond , Grey Gabrielle , Aimola Lina , Nicholas Richard , Matthews Paul
Published: March 2022

XBD173 and etifoxine are TSPO ligands that modulate inflammatory
responses in preclinical models. Limited human pharmacokinetic data is
available for either molecule, and the binding affinity of etifoxine for
human TSPO is unknown. To allow for design of human challenge
experiments, we derived pharmacokinetic data for orally administered
etifoxine (50mg TDS) and XBD173 (90mg OD) and determined the binding
affinity of etifoxine for TSPO. For XBD173, Cmax and free fraction
measurements predicted a maximal free concentration of 1.1 nM, which is
similar to XBD173 binding affinity. For etifoxine, Cmax and free
fraction measurements predicted a maximal free concentration of 0.31 nM,
substantially lower than the Ki for etifoxine in human brain derived
here (7.8uM, 95% CI 4.5-14.6uM). We conclude that oral XBD173 dosing at
90mg OD will achieve pharmacologically relevant TSPO occupancy. However,
the occupancy is too low for TSPO mediated effects after oral dosing of
etifoxine at 50mg TDS.
Anthropogenic land uses shape denitrification-related microbial communities in freshwater river ecosystems
Authors: Liu Xing , Pan Baozhu , Huang Zhenyu , Liu Xinyuan , He Haoran , Zhu Xinzheng
Published: March 2022

Microbiota play essential roles in nitrogen (N) cycling in freshwater
river ecosystems. However, microbial functional groups associated with N
cycling (especially denitrification) in freshwater rivers under
anthropogenic disturbance are still poorly understood. Here, we studied
the impacts of different land-use types on denitrification-related
microbial communities in Weihe River, Hanjiang River, and their
tributaries, in the Qinling Mountains, China. The major land-use types
in the three river areas were divided into natural (forest, shrub,
grassland, and open water) and anthropogenic (agricultural and urbanized
land) types. A landscape survey of microbiota in the river water and
sediment was carried out with extensive sample sources based on deep 16S
rRNA gene sequencing, which yielded operational taxonomic units for
predicting functional groups. With increases in proportions of
agricultural and urbanized land areas, electrical conductivity, total N,
ammonium-N, and nitrate-N all increased in water samples. Conversely,
microbial diversity exhibited a decreasing trend in water samples,
whereas the relative abundance of denitrification-related functional
groups increased, with increases in the proportions of agricultural and
urbanized land areas. The relative abundances of denitrification- and
human-related microbial functional groups in sediment samples were
distinctively higher in Weihe River (mainly under agriculture and
urbanization), when compared with those of Hanjiang River and Qinling
tributaries (dominated by forests). The results indicate that
anthropogenic land-use types, such as agricultural and urbanized land,
result in simple microbial community structure and stimulate
microbe-mediated denitrification in freshwater rivers.
Yaprak Yayların Parametrik Sonlu Elemanlar Analizi ve Yapay Sinir Ağı ile Modellenmesi
Authors: YAVUZ Serdinç , ÖZKAN M. Tolga
Published: March 2022

Yaprak yaylar özellikle büyük yüklemeler altında, yükler karşısında oluşan titreşimleri minimize etmek için kullanılırlar. Özellikle ağır vasıta araçlarda yüklemelerden dolayı ağır vasıta aracın; gelen yüklemeler karşısındaki dayanımını ve titreşimi azaltmak için en fazla kullanılan makine elemanlarıdır. Bu amaçla parametrik olarak dikdörtgen kesitli yaprak tasarımı yapılmıştır. Yaprak yay tasarımı için öncelikle yay katman sayısı 1-10 katman arasında ve boyutları üretici firma kataloğuna göre değişken biçimde alınarak farklı varyasyonların FEA modelleri oluşturulmuş ve analizleri gerçekleştirilmiştir. Yaprak yay katman sayısının eleman direngenliğine ve deformasyonuna etkisi bunun yanında gerilmelerdeki değişimler simülasyon edilmiştir. 1-10 arasındaki katman sayısı ve farklı kesit ölçülerindeki yay modelleri ANSYS ortamında parametrik olarak modellenmiş ve farklı yük büyükleri uygulanarak değişik varyasyonlar oluşturulmuştur. ANSYS yazılımında modelin mesh optimizasyonu gerçekleştirilmiş ve tüm varyasyonlar çözdürülmüştür. Elde edilen tasarım tipi ve yükleme şartlarına bağlı gerilme- gerinim değerleri kullanılarak bir Yapay Sinir Ağı Modeli geliştirilmiştir. Böylelikle katman sayısı, kesit ölçü büyüklükleri ve yükleme büyüklüklerine bağlı olarak yay sabiti (k), gerilme-gerinim değerleri yüksek hassasiyetle tahmin edilmesi sağlanmıştır. Tasarımcı, geliştirilen YSA modelini kullanarak Yay tasarımı hızlı, kolay ve minimum maliyetle elde edebileceği bir yaklaşım konulmuştur.
Application of Taguchi Method for Optimization of Design Parameters in Enhancement The Robust of “C” Type Snap-fits
Authors: ERDEMİR Fulya , ÖZKAN M. Tolga
Published: March 2022

Using statistical approaches, industrial product designs can be optimized quickly and reliably. The Taguchi method is a statistical approach that helps us to optimize the process parameters and help us to save time in terms of labor and cost. In this study, the optimization of the design parameters by using the Taguchi method for the design of the C-type snap-fit connection, which is one of the flexing fasteners used in many areas of the industry, was investigated. The design and analysis of the study was carried out by using ANSYS software. The design parameters were optimized and the effective parameters were determined. ANOVA analysis was performed to determine the effective parameters. In addition, full factorial analysis was performed to verify the method used. For example, the optimum normal stress value obtained with the Taguchi array was obtained for the combination of H1=0.4;R1=3;α1=40;α2=89;y=6 and material is PLA. When we examine the table in Figure 4, we can see that the result of 328740.27 among 729 test results and the result of the parameters in the Taguchi set match.
Penerapan Model Discovery Learning Dalam Upaya Meningkatkan Kemampuan Pemahaman Matematis Dan Pemecahan Masalah Matematis
Authors: Mugni Abdul , Turmudzi Didi , G. Kartasasmita Bana
Published: March 2022

The research of mix method with the type of embedded design is aimed to know the improvement and the difference of the improvement of mathematical understanding ability and mathematical problem solving ability among the students who get the discovery learning model with the students who get the conventional learning. The population in this study is all students of class VII MTs Persis Pasirwangi with two classes of samples, namely: class VII-C using discovery learning model and class VII-D using conventional learning. Instruments used in research: mathematical comprehension ability test and mathematical problem solving ability. From result of research analysis obtained: 1). There is no difference in the improvement of students' mathematical understanding among students who get discovery learning model with students who get conventional learning, 2). There is a difference in the ability of students to solve mathematical problems between students who get discovery learning model with students who get conventional learning in terms of KAM (High, Medium, and Low), 3) .Effect size of learning discovery learning to improve understanding ability and problem solving ability mathematically fall into the category of being.
Hasil Belajar Matematika Siswa Menggunakan Media Gambar Dengan Media Model Padat Pada Materi Geometri
Authors: Rohman Pupung Syaeful , Susianti Lusi , Jamaludin Mohamad
Published: March 2022

Penelitian ini bertujuan untuk menganalisis hasil belajar matematika siswa pada materi geometri yang pembelajarannya menggunakan media gambar dengan media model padat. Metode penelitian yang digunakan adalah kuasi eksperimen. Populasi dalam penelitian ini adalah seluruh siswa kelas V MI PUI Dermayu Sindang Indramayu dengan jumlah 119 siswa yang terbagi menjadi 3 kelas dengan mengambil sampel 2 kelas secara acak kelas dengan teknik simple random sampling. Instrumen untuk mengukur hasil belajar berupa tes dalam bentuk soal uraian. Teknik analisis datanya menggunakan uji statistik. Kesimpulan dari hasil penelitian bahwa (1) hasil belajar siswa yang menggunakan media model padat lebih tinggi dibandingkan dengan hasil belajar siswa yang menggunakan media gambar; (2) terdapat perbedaan hasil belajar matematika siswa pada materi geometri antara siswa yang pembelajarannya menggunakan media gambar dengan media model padat; (3) penggunaan media model padat pada pembelajaran matematika dengan materi geometri pada penelitian ini lebih baik dibandingkan dengan penggunaan media gambar.