bluuebunny/crossref_metadata_2025 huggingface dataset:
PECULIARITIES OF FOLLICULAR EPITHELIUM PROLIFERATION IN ADENOMAS OF THE THYROID GLAND
Authors: Khaziev Vadym , Goydenko N. I. , Gorgul N. G.
Published: June 2022

Among adenomas of the thyroid gland, microfollicular adenomas predominate

structures (47.67%). The study of the processes of hyperplasia of the follicular epithelium in adenomas of different types of structure showed that the proliferation of the follicular epithelium

it develops most intensively in microfollicular and solid adenomas with an increase in proliferates of structural and cellular atypia. Definition of optical

DNA density revealed a significantly higher level in microfollicular and solid adenomas in comparison with other forms of adenomas. Appearance of papillary structures

as a variant of hyperplasia indicates that hyperplasia may occur without symptoms maturation and formation of typical structures of thyroid tissue
TOXICOLOGIST'S VIEW ON ANTUCOTHERAL DRUG WITH ANTIESTROGEN ACTION TAMOXIFEN
Authors: Melnykivska N. V. , Kudrya M. Ya. , Kozar V. V. , Ustenko N. V. , Kudrya O. V. , Zhurakovskaya M. V. , Pavlenko T. O.
Published: June 2022

An analysis of the literature on the toxic properties of tamoxifen, which. characterized by high carcinogenic potential, embryo- and hepatotoxicity, adverse effects on the reproductive system of experimental animals

both articles. The results of our own experimental studies show that that features of toxic action of drug in the conditions of epicutaneous and inhalation

exposures include immunosuppression, rat liver dysfunction and the development of endogenous intoxication due to the accumulation of medium molecular weight peptides and

products of lipid peroxidation
INVESTIGATION OF MICROSTRUCTURE OF INTERNAL ORGANS OF EXPERIMENTAL ANIMALS AFTER FENCUCINAL OINTMENT APPLICATIONS
Authors: Sergienko L. Yu. , Kustova Svitlana , Kudrya M. Ya. , Kartavtseva O. V. , Cherevko G. M. , Boyko Maryna , Tolmachova L. M. , Zhurakovskaya M. V. , Pavlenko T. O.
Published: June 2022

Histological examinations of the microstructure of the internal organs of experimental animals were performed, which received ointment dermally for one month.

fensuccinal at a dose of 2500 mg / kg body weight. Under these experimental conditions, no damaging effect of fensuccinal ointment on the organs of experimental animals was detected.
RISK FACTORS OF DISORDERS OF PUBERTY IN BOYS - RESIDENTS OF VILLAGE AND CITY
Authors: Varodova O. V. , Bagatska N. V.
Published: June 2022

The genetic burden and environmental risk factors for puberty were examined based on genealogical analysis of 107 families of boys with delayed puberty in rural and urban areas. It was revealed that the hereditary burden of reproductive system disorders in the families of boys with delayed sexual development, city residents, is recorded much more often than among rural residents. It should be noted the high prevalence of bad habits among parents and boys in rural areas.
CLINIC AND TREATMENT OF SILV-LOSING SYNDROME IN CONGENITAL DYSFUNCTION OF THE ADRENAL CORE
Authors: Bolshova O. V.
Published: June 2022

Congenital dysfunction of the adrenal cortex (adreno-genital syndrom, congenital hyperplasia of the adrenal cortex) - a group of heterogeneous hereditary diseases, which are based on the primary violation of steroidogenesis in the cortical substance of the adrenal glands, which leads

to various metabolic disorders and is manifested by clinical manifestations of changes in the rate and nature of puberty and growth disorders.
CLINICAL AND ANTHROPOMETRIC CHARACTERISTICS OF PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON-ALCOHOLIC FATTY LIVER DISEASE
Authors: Kravchun N. A. , Zemlyanitsyna O. V. , Dorosh Olena
Published: June 2022

230 patients with type 2 diabetes mellitus were examined. In 83 (36,1 %) patients non-alcoholic fatty liver disease were diagnosed. In the patients examined dispeptic and astenovegetative syndromes as well as feelings of hardness, pressure under right ribs area, skin itching were found. Clinically significant distinctions between the symptoms in patients with diabetes mellitus and non-alcoholic fatty liver disease and in patients with type 2 diabetes mellitus and non-alcoholic fatty liver disease in combination with autoimmune thyroiditis were not found.
Draft National Consensus on Diagnosis and Treatment of Acromegaly
Authors: Karachentsev Yuri , Khyzhnyak Oksana , Kravchun N. A. , Mikityuk Myroslava
Published: June 2022

During the last 15 years, views on diagnostics, treatment and criteria of the science of acromegal are significantly changed. In 2000, the working group of specialists from neuroendocrinologies, neuro-surgery and radiation therapy under the management of A. Giustina has been developed a consensus on diagnostics and acrophageal. In 2009, a group of specialists under the management of S. Melmed, a new edition of consensus was proposed, which shows the stage of provision of medical care to patients with acromegal. In the United States, Canadi, Australia, Poland, Russia and other countries, developed national consensus on diagnosis and co-treatment of this disease.
CARDIOMETABOLIC DEVELOPMENT MECHANISMS OBESITY SYNDROME
Authors: Kravchenko N. A. , Klimenko N. N.
Published: June 2022

Cardiometabolic development mechanisms Obesity syndrome
PAPILLARY THYROID MICROCARCINOMA AND FOLLICULAR THYROID ADENOMA: IMPACT OF CLINICAL ACCOMPANIEMENT
Authors: Dinets A. V. , Hulchiy M. V. , Tsimbaliuk C. M. , Olyinyk O. B.
Published: June 2022

The aim of the study was to analyze and estimate clinical and pathological features of papillary thyroid microcarcinoma concurrent with follicular thyroid adenoma. Our findings suggest PTMC accompanied by follicular thyroid adenoma to have a less aggressive biological behavior compared to pure PTMC that might be considered in routine clinical practice. Moreover, PTMC associated with follicular thyroid adenoma may have prognostic importance for closer and long-time follow up of patients.
PREVALENCE RATE OF TYPE 2 DIABETES RISK FACTORS
Authors: Kravchun N. A. , Sorokolat Yu. V. , Romanova I. A. , Kazakov Alexandr , Suprunova V. A. , Gubareva T. I.
Published: June 2022

Type 2 diabetes risk factors were examined based on the screening of municipal clinics. We revealed a significant prevalence of hypertension, overweight, obesity, family history of diabetes and other endocrine diseases among examined subjects, and obstetric history in women. These factors are the main risk factors for type 2 diabetes. Received data justify the necessity of type 2 diabetes permanent screening not only in abovementioned clinics but also in all health care facilities with follow-up register of diabetic patients at national level.
THE LONG-TERM CONSEQUANCES OF IRRADIATION OF MALE RATS FOR REPRODUCTIVE FUNCTION OF MALE OFFSPRING AND THEIR RESISTANCE TO THE LOW DOSES IRRADIATION
Authors: Karpenko N. A.
Published: June 2022

The evaluation of the reproductive function of irradiated male rat offspring and their resistance to the low doses irradiation has been carried out. Male rats of paternal generation were irradiated by incorporated radionuclides during 45 days and the total absorbed doses (TAD) of males D3, D2 and D1 groups were 3, 9 and 94 mGy in gonads. Offspring from irradiated fathers showed normal sexual behavior. But breeding potential of offspring from fathers with TAD 94 mGy was decreased up to 67,6 % by reason of the increase of intrauterine losses in pregnant female. The sibs were irradiated in the same dose as their fathers (TAD 4 mGy) from 2–2,5 till 6–6,5 months. Breeding potentials of irradiated progeny of irradiated fathers were identical with those of unirradiated sibs. The decrease (on 66 %) of fertility of irradiated in first generation animals (group RA-F1-Control) was found. Discovered changes maybe reflects the adaptation of reproductive function of offspring of irradiated parents to conditions specified by chronic low doses irradiation
Long-Term Postoperative Pain Prediction Using Higher-Order Singular Value Decomposition of Intraoperative Physiological Responses: Prospective Cohort Study
Authors: Baharloo Raheleh , Principe Jose , Rashidi Parisa , Tighe Patrick
Published: June 2022

Background

Long-term postoperative pain (POP) and patient responses to pain relief medications are not yet fully understood. Although recent studies have developed an index for the nociception level of patients under general anesthesia based on multiple physiological parameters, it remains unclear whether these parameters correlate with long-term POP outcomes.

Objective

This study aims to extract unbiased and interpretable descriptions of how the dynamics of physiological parameters change over time and across patients in response to surgical procedures and intraoperative medications using a multivariate-temporal analysis. We demonstrated that there is an association (correlation) between the main features of intraoperative physiological responses and long-term POP, which has a predictive value, even without claiming causality.

Methods

We proposed a complex higher-order singular value decomposition method to accurately decompose patients’ physiological responses into multivariate structures evolving over time. We used intraoperative vital signs of 175 patients from a mixed surgical cohort to extract three interconnected, low-dimensional, complex-valued descriptions of patients’ physiological responses: multivariate factors, reflecting subphysiological parameters; temporal factors, reflecting common intrasurgery temporal dynamics; and patients’ factors, describing interpatient changes in physiological responses.

Results

Adoption of the complex higher-order singular value decomposition method allowed us to clarify the dynamic correlation structure included in the intraoperative physiological responses. Instantaneous phases of the complex-valued physiological responses of 242 patients within the subspace of principal descriptors enabled us to discriminate between mild and not-mild (moderate-severe) levels of pain at postoperative days 30 and 90. Following rotation of physiological responses before projection to align with the common multivariate-temporal dynamic, the method achieved an area under curve for postoperative day 30 and 90 outcomes of 0.81 and 0.89 for thoracic surgery, 0.87 and 0.83 for orthopedic surgery, 0.87 and 0.88 for urological surgery, 0.86 and 1 for colorectal surgery, 1 and 1 for transplant surgery, and 0.83 and 0.92 for pancreatic surgery, respectively.

Conclusions

By categorizing patients into different surgical groups, we identified significant surgery-related principal descriptors. Each of them potentially encodes different surgical stimulation. The dynamics of patients’ physiological responses to these surgical events were linked to long-term POP development.
Telehealth and Intimate Partner Violence: A Systematic Review of Telehealth Interventions
Authors: Chan Georgia Yin Chun , Cruz-Sánchez Margarita , Bhuptani Prachi H , Millman Christopher , Orchowski Lindsay M
Published: June 2022

Background

Intimate partner violence (IPV) is a global public health problem and often leads to deleterious outcomes. IPV is associated with elevated psychological distress, impaired physical health, and high rates of morbidity and mortality. Since the start of the COVID-19 pandemic in December 2019, there has been an exponential increase in the rates of IPV worldwide. The COVID-19 pandemic has also heralded an increased use of telehealth to deliver medical and psychological services. Telehealth is defined as the use of technology communication systems (ie, mobile apps, videoconferencing, etc) in the provision of health care. Given increases in access to Wi-Fi and computing technology, telehealth has become increasingly popular in all types of health care interventions, including those for IPV.

Objective

Reviewing and synthesizing information on telehealth intervention, screening, and prevention for IPV is essential for our knowledge of the efficacy and future of telehealth in IPV. Accordingly, this study conducted a systematic review of telehealth interventions for IPV, with a focus on screening and intervention for IPV victimization and perpetration.

Methods

This study applied the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines to a literature search that identified research evaluating telehealth and telemedicine interventions for DV and IPV. Only 14 studies met the study inclusion criteria, with 3 articles focusing on telehealth screening for IPV and 11 articles studying telehealth interventions for IPV.

Results

The studies demonstrated heterogeneity in the (1) purpose of the intervention (screening, prevention, or treatment), (2) type of intervention delivered via telehealth (website vs telephone vs videoconferencing) and intervention dosage, and (3) outcomes assessed. Scientific rigor according to the Oxford Center for Evidence-Based Medicine was also variable. Studies predominantly focused on women. The results show promising evidence of the efficacy of telehealth screening (over face-to-face screening) for IPV victimization. Only specific types of telehealth interventions were shown to have promise for reducing psychological distress among IPV survivors. The results suggest that telehealth may be a viable option for the delivery of IPV screening and intervention programs, especially when face-to-face interaction is not feasible.

Conclusions

The present findings highlight the growing utilization of telehealth modalities for IPV screening and intervention. Further research is needed to enhance the evidence base for the telehealth screening, prevention, and intervention of IPV and to evaluate the effectiveness of the approaches for individuals involved in IPV.

Conflicts of Interest

None declared.
Pretrained Transformer Language Models Versus Pretrained Word Embeddings for the Detection of Accurate Health Information on Arabic Social Media: Comparative Study (Preprint)
Authors: Albalawi Yahya , Nikolov Nikola S , Buckley Jim
Published: June 2022

BACKGROUND

In recent years, social media has become a major channel for health-related information in Saudi Arabia. Prior health informatics studies have suggested that a large proportion of health-related posts on social media are inaccurate. Given the subject matter and the scale of dissemination of such information, it is important to be able to automatically discriminate between accurate and inaccurate health-related posts in Arabic.

OBJECTIVE

The first aim of this study is to generate a data set of generic health-related tweets in Arabic, labeled as either accurate or inaccurate health information. The second aim is to leverage this data set to train a state-of-the-art deep learning model for detecting the accuracy of health-related tweets in Arabic. In particular, this study aims to train and compare the performance of multiple deep learning models that use pretrained word embeddings and transformer language models.

METHODS

We used 900 health-related tweets from a previously published data set extracted between July 15, 2019, and August 31, 2019. Furthermore, we applied a pretrained model to extract an additional 900 health-related tweets from a second data set collected specifically for this study between March 1, 2019, and April 15, 2019. The 1800 tweets were labeled by 2 physicians as accurate, inaccurate, or unsure. The physicians agreed on 43.3% (779/1800) of tweets, which were thus labeled as accurate or inaccurate. A total of 9 variations of the pretrained transformer language models were then trained and validated on 79.9% (623/779 tweets) of the data set and tested on 20% (156/779 tweets) of the data set. For comparison, we also trained a bidirectional long short-term memory model with 7 different pretrained word embeddings as the input layer on the same data set. The models were compared in terms of their accuracy, precision, recall, F1 score, and macroaverage of the F1 score.

RESULTS

We constructed a data set of labeled tweets, 38% (296/779) of which were labeled as inaccurate health information, and 62% (483/779) of which were labeled as accurate health information. We suggest that this was highly efficacious as we did not include any tweets in which the physician annotators were unsure or in disagreement. Among the investigated deep learning models, the Transformer-based Model for Arabic Language Understanding version 0.2 (AraBERTv0.2)-large model was the most accurate, with an F1 score of 87%, followed by AraBERT version 2–large and AraBERTv0.2-base.

CONCLUSIONS

Our results indicate that the pretrained language model AraBERTv0.2 is the best model for classifying tweets as carrying either inaccurate or accurate health information. Future studies should consider applying ensemble learning to combine the best models as it may produce better results.
Telehealth and Intimate Partner Violence: A Systematic Review of Telehealth Interventions (Preprint)
Authors: Chan Georgia Yin Chun , Cruz-Sánchez Margarita , Bhuptani Prachi H. , Millman Christopher , Orchowski Lindsay M.
Published: June 2022

BACKGROUND

Intimate partner violence (IPV) is a global public health problem and often leads to deleterious outcomes. IPV is associated with elevated psychological distress, impaired physical health, and high rates of morbidity and mortality. Since the start of the COVID-19 pandemic in December 2019, there has been an exponential increase in the rates of IPV worldwide. The COVID-19 pandemic has also heralded an increased use of telehealth to deliver medical and psychological services. Telehealth is defined as the use of technology communication systems (ie, mobile apps, videoconferencing, etc) in the provision of health care. Given increases in access to Wi-Fi and computing technology, telehealth has become increasingly popular in all types of health care interventions, including those for IPV.

OBJECTIVE

Reviewing and synthesizing information on telehealth intervention, screening, and prevention for IPV is essential for our knowledge of the efficacy and future of telehealth in IPV. Accordingly, this study conducted a systematic review of telehealth interventions for IPV, with a focus on screening and intervention for IPV victimization and perpetration.

METHODS

This study applied the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines to a literature search that identified research evaluating telehealth and telemedicine interventions for DV and IPV. Only 14 studies met the study inclusion criteria, with 3 articles focusing on telehealth screening for IPV and 11 articles studying telehealth interventions for IPV.

RESULTS

The studies demonstrated heterogeneity in the (1) purpose of the intervention (screening, prevention, or treatment), (2) type of intervention delivered via telehealth (website vs telephone vs videoconferencing) and intervention dosage, and (3) outcomes assessed. Scientific rigor according to the Oxford Center for Evidence-Based Medicine was also variable. Studies predominantly focused on women. The results show promising evidence of the efficacy of telehealth screening (over face-to-face screening) for IPV victimization. Only specific types of telehealth interventions were shown to have promise for reducing psychological distress among IPV survivors. The results suggest that telehealth may be a viable option for the delivery of IPV screening and intervention programs, especially when face-to-face interaction is not feasible.

CONCLUSIONS

The present findings highlight the growing utilization of telehealth modalities for IPV screening and intervention. Further research is needed to enhance the evidence base for the telehealth screening, prevention, and intervention of IPV and to evaluate the effectiveness of the approaches for individuals involved in IPV.
Network pharmacology of black cumin (Nigella sativa L.) as a candidate of OMAI in colorectal cancer: in silico study
Authors: Firzannida Firzannida , Bagaskara Sakti , Savira Savana Sonia , Fadnurrahim Aufa , Rofida Siti
Published: June 2022

Colorectal cancer is the third most common cancer globally and the second leading cause of cancer‐related deaths. The management of colorectal cancer requires consideration of various factors due to the non‐selectivity of drugs, meaning that highly effective treatment with lower side effects is needed. Black cumin (Nigella sativa L.) contains thymoquinone and various other metabolites with potential as anticancer effects. The involvement of various genes and the difficulty of drug development have led to a ashift in the drug development paradigm towards plant‐based medicine that is both multicomponent and synergistic in supporting the resulting pharmacological effects. Network pharmacology can predict the synergistic effect of a multicomponent approach. This study aimed to predict the network pharmacology of black cumin as a candidate for OMAI (“Obat Modern Asli Indonesia”, Indonesian‐origin modern medicine) in colorectal cancer. This research was an in silico study using various ethnobotanical databases and software. The results show that seven metabolites in black cumin are correlated with ten surface receptor proteins, 30 intracellular proteins, and mechanisms involving six colorectal cancer signaling pathways. This result indicates that Nigella sativa L. has potential in OMAI and can be a reference for the development of cancer treatment, especially for colorectal cancer.
Kemampuan Pemelajar Bahasa Jepang dalam Melafalkan Bunyi Nasal /n/ yang Diikuti Konsonan Bilabial /p/
Authors: Asnita Nadia , Febriyanti Rike
Published: June 2022

Japanese has a variety of sounds with very interesting features, but these features can cause mispronunciation, especially by foreign students. This study aims to determine the ability of Indonesian Japanese learners to pronounce the nasal consonant /n/ when followed by a bilabial consonant (両唇音) especially /p/. This study uses the descriptive qualitative method, conducted to 10 Japanese language students at Brawijaya University by analyzing their voices using Praat when reciting 3 Japanese sentences which contains [shinpai], [tenpura], and [kanpeki]. We also recorded the voice of Japanese native speakers when reciting the same sentences and use it as a research guide during data analyzing process. From the analysis of pronunciation by native speaker, it is found that the nasal sound produced is a labiodental nasal sound /ɱ/, and there was a stop without vibration when the mouth was closed or in Japanese known as “heisa” (閉鎖) which caused a bilabial popping sound when pronouncing the /p/ sound after the nasal. While for students, it is found that they had several pronunciations similar to the native speaker, but most of them are different pronunciations. The different pronunciations were found in the form of nasal sounds pronounced /n/ only or /m/ only. Some even spell /ng/, and some did not produce pops at the bilabial sound /p/, and other distinct pronunciation were also found in this research.
ПОТЕНЦИАЛ ОТЕЧЕСТВЕННОГО АЛМАЗА. ТЕПЛООТВОДЫ
Authors: Колядин А. , Лучинин В. , Ягудаев Ю. , Бохов О. , Ильин С. , Клепиков И. , Ножкина А.
Published: June 2022

Рассмотрены современное состояние и конструктивные особенности теплоотводов как одного из критических факторов электроники и фотоники с экстремальными режимами и условиями эксплуатации. Представлены результаты анализа мирового и российского рынка производителей синтетических алмазов для теплоотводов. На основе анализа публикационной и патентной активности оценены инновационность и потенциал развития алмазных теплоотводов.
АВТОМАТИЧЕСКАЯ УСТАНОВКА КЛИНОВОГО МОНТАЖА ПРОВОЛОЧНЫХ МЕЖСОЕДИНЕНИЙ МАЛОГО ДИАМЕТРА 2,5D ЭЛЕКТРОННЫХ МОДУЛЕЙ
Authors: Петухов И.
Published: June 2022

Описаны проблемы, возникающие при высокопроизводительном монтаже проволочных межсоединений в многокристальных сборках, в частности, в 2,5D-конструкциях с большим значением разновысотности уровней сварки. Приведены основные характеристики установки УЗ-микросварки ЭМ‑4520, производимой белорусской компанией «Планар-­СО», и ее сварочной системы, обеспечивающей такой монтаж.
Sobre César Manrique Figueroa, El libro flamenco para lectores novohispanos. Una historia internacional de comercio y consumo libresco
Authors: Moreno Gamboa Olivia
Published: June 2022

Reseña sobre César Manrique Figueroa, El libro flamenco para lectores novohispanos. Una historia internacional de comercio y consumo libresco (México: Universidad Nacional Autónoma de México, Instituto de Investigaciones Bibliográficas, 2019).
Face Mask Detection Alert System Using Deep Learning
Authors: Jagan Dr. A. , Ganesh P. , Balapriya R.
Published: June 2022

Abstract: Covid-19 pandemic has brought significant by spreading as of recently everywhere on the world. The effect of COVID-19 has been fallen on practically all areas of development. The medical services framework is going through an emergency. Numerous prudent steps have been taken to lessen the spread of this illness where wearing a mask is one of them. In this paper, an effective way is proposed that confine the development of Corona virus by discovering individuals who are not wearing any facial mask in a brilliant city network where Closed-Circuit Television (CCTV) cameras make close observance. While an individual without a mask is identified, the relating authority is educated through the city organization.
Mechanical Vibration System with Dynamic Displacement of Long Suspension Bridge
Authors: Singh Manpreet , Kumar Er. Ashok
Published: June 2022

Abstract: This work presents an algorithm that automatically identifies the equivalent mass and speed of vehicles crossing a long-span suspension bridge utilizing ambient vibrations data. The first goal is to estimate vehicle characteristics that can be further used to gather information about the level of serviceability loading of the bridge, as well as provide relevant data for smart asset management. Sensors are used to measure the vibrations and secondary inputs to the system are used to actuate the flexible body in order to obtain some desired structural response. As that, for longer span bridges the change in stiffness of the track has a negligible effect on the acceleration and displacement. All analysis have done using MATLAB tool.
Does Size Matter in the Airline Industry?
Authors: Malhotra D K , Russel Philip
Published: June 2022

Over the last decade, the U.S. airline industry has transformed itself through mergers, restructurings, bankruptcies, and dissolutions. Also during this time, the airline industry focused on a business model that was driven by an emphasis on asset utilization. This was driven by increasing the load factor to increase cost efficiencies through economies of scale so that the return on invested capital could be improved by reducing the operating costs. This study evaluates economies of scale and resultant cost efficiencies in the U.S. passenger airline industry for the period 2013 to 2018. The research finds that the airline industry is experiencing cost efficiencies with every increase in the size of the airline, but cost efficiencies are not evenly distributed. The paper also finds that the main source of cost efficiency appears to be aircraft maintenance expenses.
Word-formation complexity: a learner corpus-based study
Authors: Lyashevskaya Olga Nikolaevna , Pyzhak Julia Vyacheslavovna , Vinogradova Olga Il'inichna
Published: June 2022

This article explores the word-formation dimension of learner text complexity which indicates how skilful the non-native speakers are in using more and less complex - and varied - derivational constructions. In order to analyse the association between complexity and writing accuracy in word formation as well as interactive effects of task type, text register, and native language background, we examine the materials of the REALEC corpus of English essays written by university students with Russian L1. We present an approach to measure derivational complexity based on the classification of suffixes offered in Bauer and Nation (1993) and then compare the complexity results and the number of word formation errors annotated in the texts. Starting with the hypothesis that with increasing complexity the number of errors will decrease, we apply statistical analysis to examine the association between complexity and accuracy. We found, first, that the use of more advanced word-formation suffixes affects the number of errors in texts. Second, different levels of suffixes in the hierarchy affect derivation accuracy in different ways. In particular, the use of irregular derivational models is positively associated with the number of errors. Third, the type of examination task and expected format and register of writing should be taken into consideration. The hypothesis holds true for regular but infrequent advanced suffixal models used in more formal descriptive essays associated with an academic register. However, for less formal texts with lower academic register requirements, the hypothesis needs to be amended.
Taubat Pelaku Pembunuhan Sengaja dalam Al-Qur’an
Authors: Simangunsong Ali Abdurahman , Zaini Muhammad , Fadhli Muhajirul
Published: June 2022

Taubat is one of the religious commandments that man must do. In the Koran, there are many verses that command to repent. On the other hand, the act of killing deliberately is regarded by some mufasir as an act that which there is no repentance (taubat) for the perpetrator. This study wants to see what verses in the Koran are indicated to have a connection with taubat for perpetrators of intentional murder and its interpretation and how the mufasir views related to taubat for perpetrators of intentional murder. This research is a library study and the data is presented using thematic methods. The mufasir referred to in this study are Ibn Katsīr, Hamka, M. Quraish Shihab, al-Qurthubi and Wahbah al-Zuhaili. The results showed that some scholars from salāf circles argued that it was not accepted by people who had committed intentional killings. Meanwhile, the scholars of both salāf and khalāf hold the view that people who have committed the act of killing intentionally still have the opportunity to repent to Allah. Then in an effort to repent, the mufasir took the view that whoever repents of the deeds of wrongdoings earnestly and cheerfully and works righteous charity, then Allah will abolish His torment and bestow upon him a reward. Taubat merupakan salah satu dari perintah agama yang harus dilakukan manusia. Di dalam Alquran, terdapat banyak ayat yang memerintahkan untuk bertaubat. Di sisi lain, perbuatan membunuh dengan sengaja dianggap oleh sebagian mufasir sebagai perbuatan yang tidak ada taubat bagi pelakunya. Kajian ini ingin melihat ayat-ayat apa saja di dalam Alquran yang terindikasi memiliki kaitan dengan taubat bagi pelaku pembunuhan sengaja dan penafsirannya serta bagaimana pandangan mufasir terkait taubat bagi pelaku pembunuhan sengaja. Penelitian ini bersifat kajian perpustakaan dan data yang disajikan dengan menggunakan metode tematik. Para mufasir yang menjadi rujukan dalam kajian ini adalah Ibnu Katsīr, Hamka, M. Quraish Shihab, al-Qurthubi dan Wahbah al-Zuhaili. Hasil penelitian menunjukkan bahwa sebagian ulama dari kalangan salāf berpendapat bahwa tidak diterima taubat dari orang yang telah melakukan pembunuhan dengan sengaja. Sementara itu, jumhur ulama dari salāf maupun khalāf memiliki pandangan bahwa orang yang telah melakukan perbuatan membunuh dengan sengaja masih memiliki kesempatan untuk bertaubat kepada Allah. Kemudian dalam upaya untuk bertaubat, jumhur para mufasir berpandangan bahwa barangsiapa yang bertaubat dari perbuatan maksiat dengan sungguh-sungguh dan penuh keridhaan, serta mengerjakan amal saleh, maka Allah akan menghapuskan siksa-Nya dan menganugerahkan kepadanya pahala.
Perfil del profesional docente de francés como lengua extranjera en Costa Rica en el escenario educativo actual debido a la pandemia ocasionada por la COVID-19
Authors: Azofeifa-Céspedes Arturo , Martínez-Bohórquez Ingrid
Published: June 2022

El objetivo de este trabajo consistió en determinar el perfil de la persona docente de francés como lengua extranjera producto de las transformaciones requeridas en el contexto educativo debido a la pandemia mundial causada por la COVID-19. Para ello, se realizó un estudio mixto de tipo descriptivo, en el cual se especificaron las características y propiedades del perfil de la persona docente de francés. El análisis de estas características se llevó a cabo desde el enfoque cuantitativo y cualitativo para interpretar de forma integral la realidad en el escenario educativo actual. Por consiguiente, el estudio se sustentó en el análisis documental, la revisión bibliográfica y la consulta a personas docentes vinculadas al campo de la enseñanza del francés como lengua extranjera dentro y fuera del país, para determinar las competencias, habilidades y destrezas requeridas para establecer un perfil integral, actual y atinente a las demandas nacionales e internacionales. Entre los principales hallazgos, se encontró que los docentes de francés tuvieron desafíos en las áreas tecnológica y pedagógica; los cambios en el ámbito educativo demandaron a la persona docente dominio de herramientas y recursos tecnológicos y capacidad de adaptación del proceso de enseñanza y aprendizaje al formato virtual y a distancia. Se concluye que el nuevo perfil docente requiere ser integral y apto a los estándares internacionales, así como nacionales.
Ley de inversiones de Uruguay: política fiscal que muestra un desempeño de interés para el estudio en Costa Rica
Authors: Ruiz-Hidalgo Helen
Published: June 2022

Se analiza la Ley de Inversiones de Uruguay y se presentan estudios con reconocimiento que dan cuenta de desempeños sociales y productivos de sus incentivos fiscales. Se estudia cómo sus beneficios compensan sus sacrificios fiscales, fortalecen el entorno productivo y promueven exportaciones. Costa Rica cuenta también con estímulos fiscales a la inversión extranjera con su Régimen de Zonas Francas y promueve exportaciones con excelentes resultados, pero no establece parámetros de rendimiento. Se plantea la relevancia del estudio de la experiencia de Uruguay porque su análisis y discusión podría servir para enriquecer el régimen de incentivos fiscales de Costa Rica.
Consideraciones relacionadas con los inductores de la innovación: Observaciones teóricas y empíricas
Authors: Alfaro-Ramos Alfredo Elías , Silva-Atencio Gabriel
Published: June 2022

El objetivo es revisar sistemáticamente la literatura empírica sobre gestión del conocimiento, capital intelectual e innovación en busca de vacíos que posibiliten futuras líneas de investigación. La investigación metodológica se orientó a la revisión documental, bajo un enfoque cualitativo. Se encuentran estudios sobre el impacto de la gestión del conocimiento y el capital intelectual por separado y en conjunto en varios tipos de innovación y en ambos casos el impacto es positivo, pero no se ha encontrado el impacto sobre la innovación del modelo de negocio; por lo tanto, se identifica un vacío en la literatura que debería ser investigado empíricamente.

Classification JEL: O31, D83, M10.
Optimasi Rute Distribusi Koran Radar Sulteng Palu Menggunakan Algoritma Genetika
Authors: Putra T S , Sahari A
Published: June 2022

Algoritma genetika merupakan suatu metode pencarian berdasarkan pada mekanisme seleksi alam. Algoritma ini digunakan untuk mendapatkan solusi dalam masalah optimasi. Masalah optimasi yang akan dibahas adalah penentuan rute terpendek dalam pendistribusian koran. Pada penelitian ini bertujuan menjelaskan aplikasi algoritma genetika untuk mencari rute terpendek pendistribusian koran di Radar Sulteng Palu. Langkah-langkah menenttukan rute terpendek menggunakan algortima genetika adalah dengan mendefinisikan rute ke dalam individu dalam sebuah populasi, menghitung nilai fitness individu, menentukan induk yang terpilih, menghasilkan individu baru dengan swapping mutation, menyusun populasi baru hingga memperoleh individu dengan nilai fitness optimum. Hasil yang diperoleh dari perhitungan menggunakan algoritma genetika dengan seleksi ranking adalah rute pendistribusian koran di Radar Sulteng Palu sejauh 41,32 km. Rute ditetaokan setelah nilai fitness mengalami konvergen pada generasi ke-7. Nilai fitness yang mengalami konvergen adalah 0,0242.
Liderazgo transformacional como factor potenciador del talento humano en instituciones educativas
Authors: Contreras Mora Edward
Published: June 2022

El presente es el momento uno de la investigación llevada a cabo como candidato a Doctor en Ciencias Gerenciales de la Universidad Rafael Belloso Chacín de la ciudad de Maracaibo-Venezuela. En él se presenta desde el abordaje del fenómeno al acercamiento de la investigación, mediante el tratamiento teórico, la descripción de la situación, se exponen las reflexiones, interrogantes, premisas, propósitos, razones y contexto de la investigación. Se ha tomado como antecedentes todo lo relacionado con el liderazgo y sus diversas orientaciones con el paso de los años, además de su relación con el talento humano. La metodología utilizada es el análisis documental en profundidad de diversas percepciones sobre el tema abordado, de igual manera, se analiza el contexto donde se lleva a cabo la investigación. Ello permite comprender la importancia del liderazgo transformacional, como la herramienta que permita a todos los integrantes de una organización involucrarse con sus diferentes acciones, para alcanzar los propósitos planteados. Se ratifica la importancia de que el gerente encuentre diversas estrategias, para que, gracias a su influencia positiva en el talento humano, se propicie el desarrollo tanto de cada individuo como el de la organización que está bajo su tutela.
Análisis del nivel de madurez de la gestión del conocimiento para cuatro Mipymes industriales del barrio Restrepo en Bogotá-Colombia
Authors: Castellanos Narciso José Ever , Rico Noy Pilar Andrea
Published: June 2022

La presente investigación se enmarca dentro de la Especialización de Gestión de Proyectos en la línea investigativa de Gestión de la Innovación y del Conocimiento, perteneciente a la Escuela de Ciencias Administrativas, Contables, Económicas y de Negocios ECACEN, de la Universidad Nacional Abierta y a Distancia, UNAD, en Bogo-tá, Colombia. Busca dar cuenta del nivel de madurez de cuatro Mipymes industriales del barrio Restrepo en Bogotá, mediante una metodología cualitativa y un trabajo de campo que, desde la opinión de la comunidad, determine un acercamiento al estado del nivel de madurez de la Gestión del Conocimiento en las mismas, teniendo en cuenta su estado actual en el contexto local, regional, nacional y global, y la importancia de la Gestión del Conocimiento en las organizaciones frente a las dinámicas del mundo, el mercado y la economía actual. Para lograr estos objetivos el estudio se divide en las siguientes secciones: el contenido o marco referencial, que detalla los temas más importantes tratados en la investigación como gestión del conocimiento, nivel de madurez y Mipymes, entre otros; los resultados, que son obtenidos como consecuencia de la aplicación del instrumento de investigación, donde se analiza a las cuatro Mipymes industriales objeto de estudio y sus niveles de Madurez de Gestión del Conocimiento; en la siguiente sección se dan propuestas y recomendaciones para las cuatro Mipymes industriales; y por último, se describen las principales conclusiones del estudio.
Modelo de emprendimiento género e inclusión social
Authors: Palencia Fajardo Ofelia
Published: June 2022

Considerando la mujer como un actor activo del emprendimiento rural y urbano se genera un modelo para evaluar el emprendimiento femenino, acorde a la políticas públicas de Colombia (Martínez-Vega, 2018), en grupos organizados, es así como se pretende caracterizar las mujeres emprendedoras del departamento del Huila, considerando su exclusión, marginalidad, explotación, grado de dependencia, mediante el análisis de variables independientes, dependientes y de control, lo cual se hace mediante una acción participativa. Se tuvo en cuenta la contribución de: Díaz, Hernández, Sánchez y Postigo (2010), con los aportes a la teoría del género. Un estudio comparativo; Bonan y Guzmán (2007), aportes de la teoría de género a la comprensión de las dinámicas sociales y los temas específicos de asociatividad, participación identidad y poder; Henríquez-Daza et al.(2010), la creación de empresas en Colombia bajo las percepciones femenina y masculina; Torrente-Castro (2016), estudio de caso en la asociación de mujeres cafeteras del occidente del Huila; ISO 26000 (2010), guía de responsabilidad social empresarial para evaluar la responsabilidad de las empresas en la siete materias fundamentales. El modelo comprende los factores de análisis: exclusión, marginalidad, grado de explotación y dependencia, partiendo de los supuestos que las mujeres son más organizadas que los hombres en relación con estructuras de emprendimiento, que tienen metas a corto plazo con visión de mercado a largo plazo y que para que las Mipymes sean competitivas en los mercados nacionales e internacionales deben asumir como estrategia la asociatividad. La metodología utilizada en la investigación es la exploratoria y explicativa basada en literatura, antecedentes investigativos y acercamiento a grupos asociativos, considerando las siguientes hipótesis: 1. Las mujeres son más organizadas que los hombres en relación con estructuras de emprendimiento y tienen metas a corto plazo con visión de mercado a largo plazo. 2. Para que las Mipymes sean competitivas en los mercados nacionales e internacionales deben asumir como estrategia la asociatividad.
North American barren-ground caribou cycles are driven by logistic trophic dynamics
Authors: Bongelli Eric , Dowsley Martha , Cluff Dean , Campbell Mitch , Taylor Mitchell
Published: June 2022

We used the Qamanirjuaq, Bathurst, and George River barren-ground
caribou sine cycles to project numbers (Nt), calculate subpopulation
annual growth rates (λt) and calculate logistic carrying capacity (Kt).
Maximum annual growth rate was 1.196 and maximum annual rate of decline
was 0.836 for the harvested Qamanirjuaq subpopulation sine cycle.
However, the maximum annual subpopulation growth rates for both the
harvested Bathurst and George River subpopulation sine cycles were
greater than the biologically possible maximum intrinsic rate of
increase during the eruption phase. Subpopulation numbers for
Qamanirjuaq, Bathurst and George River barren-ground caribou
subpopulations all closely tracked carrying capacity for one complete
cycle with lag times between Nt and Kt ranging from < 1-year
to approximately 5-years. The short lag times observed indicates that
Qamanirjuaq, Bathurst and George River barren-ground caribou
subpopulations closely track their range condition. Range condition
drives barren-ground caribou subpopulation cycles, but range condition
also cycles; presumably because annual barren-ground caribou grazing
rates are proportional to barren-ground caribou numbers and eventually
exceed range annual growth rates. Immigration from adjacent
subpopulations plays a role in the initiation and acceleration of the
eruption period in some subpopulations, but not all of them. Numerical
synchrony and asynchrony with adjacent subpopulation cycles can affect
the timing of the eruption phase through mediation of immigration. Once
subpopulation range has recovered, the rapid recovery of subpopulation
numbers suggest that subpopulations are not restricted by other factors.
The regularity and symmetry of both the increase and decline phases of
these cycles suggests that the barren-ground caribou cycle is both
stable and resilient. Continuation of barren-ground caribou cycles at
historical levels is likely if habitat conservation measures are adopted
so that annual migration patterns are not disrupted, summer and winter
range remain undisturbed and common-sense harvest management policies
are adopted when caribou are at low numbers.
Tricuspid annular disjunction can be isolated and even arrhythmogenic. A cardiac magnetic resonance study
Authors:   Cardiac Magnetic Resonance Unit, “Di Summa–Perrino” Hospital, Brindisi, Italy, Mangini Francesco , Muscogiuri Eluisa ,   Cardiac Magnetic Resonance Unit, “Di Summa–Perrino” Hospital, Brindisi, Italy, Del Villano Roberto ,   Cardiac Magnetic Resonance Unit, “Di Summa–Perrino” Hospital, Brindisi, Italy
Published: June 2022

Mitral annular disjunction is related to increased arrhythmogenic risk; in a certain percentage of cases, mitral annular disjunction is associated with tricuspid annular disjunction. While the prognostic implications of mitral annular disjunction have been well established, there is still little data to define this aspect regarding the tricuspid annular disjunction. We present a case of a patient admitted for life-threatening ventricular arrhythmias that occurred during endurance sporting activity, who was found to have isolated tricuspid annular disjunction, not associated with mitral annular disjunction. Based on several factors, including the morphology and axis of QRS of the ventricular arrhythmic activity, and its behavior, including the response to antiarrhythmic treatment, and in keeping with the finding of edema and late gadolinium enhancement at the basal segment of the right ventricle free wall on cardiac magnetic resonance imaging, a direct relation between tricuspid annular disjunction and ventricular arrhythmias was highly conceivable. Control after three months showed almost complete remission of the previously described and persistence of LGE at the level of the basal segment of the free wall of the right ventricle, so giving strength to the hypothesis of an event related to increased acute RV free wall stress, secondary to high-intensity physical activity, established on a framework of chronic wall stress, as represented by LGE, similarly to what happens for mitral valve prolapse. To the best of our knowledge, this is the first case of a legitimately conceivable direct relation between tricuspid annular disjunction and ventricular arrhythmias.
Ten years of clinical experience with cyanoacrylate glue for venous access in a 1300-bed university hospital
Authors: Pittiruti Mauro , Annetta Maria Giuseppina , Marche Bruno , D’Andrea Vito , Scoppettuolo Giancarlo
Published: June 2022

In the past decade, cyanoacrylate glue has been progressively introduced into the clinical practice of venous access devices used for different purposes. Glue has been used to increase device stabilisation (to reduce the risk of catheter dislodgement), to seal the exit site (to both reduce local bleeding and decrease the risk of bacterial contamination) and to close skin incisions required for the insertion of tunnelled catheters or totally implanted venous ports. For many of these purposes, the efficacy and cost-effectiveness of cyanoacrylate glue has been demonstrated, while some indications are still controversial. This article reports on 10 years of clinical experience with cyanoacrylate glue in a large university hospital, and provides a narrative review of the scientific evidence on the benefits of glue in venous access that has been accumulating over the past decade.