bluuebunny/crossref_metadata_2025 huggingface dataset:
SPANISH-GERMAN COLLABORATION IN BIOCHEMISTRY MAINTAINED BY MEMBERS OF THE ROYAL ACADEMY NATIONAL OF PHARMACY AND BY OTHER SPANISH BIOCHEMISTS
Authors: Cabezas Fernández del Campo José Antonio
Published: July 2021

German can be considered as world pioneer in the development of Biochemistry. Its founder, Prof. Felix von Hoppe-Seyler, established contacts with the Spanish Professor of Organic Chemistry, Laureano Calderón Arana, since the onset of this subject around 1872. Later, some other Professors of the newly created Química Biológica, which was taught only at the Faculty of Pharmacy in Madrid as a subject common to doctoral students in Pharmacy, Medicine and Science, maintained a connection, albeit minor, with their German colleagues. From 1928, Dr. Severo Ochoa, who would subsequently win a Nobel Prize, worked for long periods in the prestigious Departments at Berlin and Heidelberg. More recently, other biochemists, members of the Royal Academy National of Pharmacy (RANF), have followed this connection with several German Departments. Furthermore, German biochemists have delivered lectures in Spanish Universities invited by their Spanish colleagues, in addition to their participation in Spanish symposia. Moreover, several German biochemists have been RANF members
HOLISTIC MANAGEMENT OF HOME ARTIFICIAL NUTRITION: HUMANIZATION AND INNOVATION AT PATIENT’S SERVICE
Authors: Martínez Sesmero José Manuel
Published: July 2021

Disease-related malnutrition is a common pathology in the developed world. It affects 30 million people in Europe and it has an associated cost of one hundred and seventy billion euros per year. In Spain, around 1.7 million adults, 4.4% of total population, are negatively affected. Malnutrition affects one out of four patients on hospital admissions. It is estimated that hospitalized patients who are malnourished throughout their stay range from 23.7% to 37%; sharpening these figures for multi-patients over 70 years old, and almost 10% are disensuaded during their hospital stay. All this implies an increase in hospital stays and associated costs; in particular, the direct costs of hospital malnutrition were estimated at 1.143 million annually in 2009, representing 1.8% of health expenses within the national health system. Advances in technology and infrastructure have facilitated the transfer of complex hospital-to-home services. Nowadays, the international trend points to the increasing development of the domicile as a care center. A meta-analysis of 61 randomized and controlled trials, published in 2012, showed that patients treated at home had a six-month mortality rate between 19% and 38% lower than those who were hospitalized. Home artificial nutrition (HAN) is the nutrients home-administration, among other therapeutic agents, administered through the digestive tract -home enteral nutrition (HEN)- or intravenously -home parenteral nutrition (NPD-), with the objective of improving or maintaining, at home, the patient’s nutritional status. That reports into a benefit for the patient as being able to continue the family, social and work commitments. The environment, in which 21st century health professionals work, is changing significantly. There are multiple innovations in process management, given by the growing potential offered by new technologies in remote care. It supports the patient’s home stay, either in the community or in a more familiar environment, that is, in a more humanized environment. Finally, HAN is shown to be an effective-cost alternative in relation to classical hospital care, resulting in the adoption of the efficiency criterion as an element of prioritization in healthcare.
DETERMINANTS OF TECHNICAL EFFICIENCY AND TOTAL FACTOR PRODUCTIVITY CHANGE OF THE MANUFACTURING INDUSTRY IN EAST JAVA: EFFORTS TO INCREASE PERFORMANCE AND INDUSTRIAL COMPETITIVENESS
Authors: Imroatul Amaliyah
Published: July 2021

This research aims to calculate and analyze the level of technical efficiency and total factor productivity change of manufacture industry, and to examine the factors that influence the value of technical efficiency of manufacture industry in East Java. The method used for this research is Data Envelopment Analysis (DEA) and Malmquist Index with Bootstrapping approach, and Tobit regression. This research used micro data from Indonesian Large and Medium-Scale Industry Survey within the year of 2007 to 2013. The results of this research are: (1) the estimated result of DEA with bootstrapping approach using output-oriented variable return to scale (VRS) assumption shows that the level of technical efficiency of manufacture industry in East Java has been not good enough and overall, it still has the potential to increase its output to reach an efficient condition; (2) the estimated result of Tobitregression demonstrates that the level of technical efficiency of the company is influenced by the company’s size, HHI, capital labor ratio, export and types of company ownership; (3) the estimated result of Malmquist Index with Bootstrapping approach shows that theaverage of total factor productivity change (TFPCH) of manufacture industry from 2007 to 2013 hasexhibited a positive change. The main factor that affects TFPCH, in order, are technological change, efficiency change, and efficiency scale change.
KEWAN PITIK (APLIKASI PEMANTAUAN, KONTROL DAN KEAMANAN KANDANG AYAM DENGAN GOOGLE FIREBASE BERBASIS INTERNET OF THINGS)
Authors: Ikhwan Fathulloh Muhammad , Takwim Ahsani , Aji Permadi Dimas , Rizaldy Shalih
Published: July 2021

Prioritas permasalahan yang dihadapi oleh UKM peternakan ayam saat ini terletak pada tata cara perawatan ayam selama beternak. Mayoritas pemberian pakan untuk ayam masih dilakukan secara manual, serta kesulitan dalam hal pengaturan suhu dalam kandang yang menyebabkan tingkat kematian ayam cukup tinggi yaitu mencapai 8% dari 1000 ekor ayam mati tiap kali ternak (35 hari). Tentunya hal ini, akan mempengaruhi pendapatan yang diperoleh UKM peternakan ayam. Tujuan dari penelitian ini adalah untuk membantu memberikan solusi terhadap permasalahan UKM peternakan ayam sehingga diharapkan dapat meningkatkan produktivitas UKM dalam upaya memenuhi kebutuhan pasar akan daging ayam. Sistem ini dapat digunakan untuk memberi pakan dan mengatur suhu secara otomatis yang dapat dikontrol dan dimonitor dari jarak jauh melalui aplikasi android dan aplikasi website dengan memanfaatkan jaringan internet.
Assessment of temperature and acid tolerance of Bacillus subtilis isolated from a Brazilian fruit juice-added soy beverage
Authors: Oliveira Renato Ventresqui , Amaral Lívio da Silva , Milagres Cristiane Aparecida , Santos Celso Tadeu Barbosa , Pelli Afonso , Paiva Aline Dias
Published: July 2021

Bacillus subtilis is a spore-forming bacterium and an important food contaminant. The aim of this study was to analyze the ability of B. subtilis spores to survive under conditions of low pH and high temperature. The package was purchased at a local supermarket, in Uberaba, Minas Gerais. A sample was collected, diluted and plated on Brain-Heart-Infusion agar (BHI). After incubation, suspected colonies of B. subtilis were transferred to BHI agar. Cell morphology, the presence of spores and Gram stain were examined, and the isolate was identified by 16S rRNA gene sequencing . The microscope evaluation indicated the presence of spores. The thermal tolerance of the spores was evaluated by the addition of 3x109spores/mL in test tubes containing peptone water. Heat treatments were carried out at 80 and 90°C at different incubation times (0, 10, 20, 30, 40, 50 and 60 min). After heating, the tubes were cooled and the number of viable spores was determined in BHI Agar. For the analysis of spore survival, D and Z values were calculated. Tolerance to acid conditions was evaluated using BHI broth with different pH values. After incubation, the bacterial concentration was determined by determining viable cell count on BHI Agar medium. The vegetative cells were transferred to the BHI broth and the pH was adjusted to different values (3, 4 or 5). Sampling were taken 8, 12 and 24 h after incubation. The samples were serially diluted in peptone water and spread in BHI Agar to determine the viable cell count . The 16S rRNA gene sequencing indicated high similarity (99.99%) with B. subtilis. D values were 17.01 min at 80°C and 13.42 min at 90°C. The Z-value was 97.13°C. B. subtilis was not able to grow at pH 3 and pH 4, but its survival was confirmed after the growth of colonies on BHI agar. At pH 5, B. subtilis grew after 24 h and the final pH changed to 7. Our results suggest that the spores of B. subtilis isolated from fruit juice-added soy beverage are tolerant to low pH and high temperature.
Las bulas papales
Authors: Toledo Espinoza Elías Saturnino , Toledo Espinoza Sipriana Lila
Published: July 2021

Las bulas son unos archivos que tratan comúnmente asuntos políticos o religiosos, en la situación de contener sello papal se sabe como bula papal o bula pontificia. Estas son expedidas por la Cancillería Apostólica Papal sobre asuntos de la gestión clerical e inclusive civil. El sello papal es una pequeña medalla de plomo con una cruz en medio y una representación de San Pedro y San Pablo y en el reverso el nombre del papa del instante y el año de pontificado. Bulas Alejandrinas es el nombre colectivo que se da al grupo de documentos pontificios: 5 manuscritos en latín sobre pergamino, los cuales tienen dentro las bulas papales concedidas en 1493 por el papa Alejandro VI, con las cuales se sientan las bases del derecho universal. En 1493, a partir del primer viaje de Colón, se originaron una secuencia de disputas entre los reinos de Portugal y España, ya que el Monarca Juan II de Portugal reclamaba todos los países descubiertos por Colón. Para Terminar con ese altercado, los Reyes Católicos, Fernando e Isabel, solicitan la participación del nuevo Papa Alejandro VI.
Peranan Orangtua Kristen Dalam Membentuk Karakter Anak
Authors: Metboki Rianto Junedi A
Published: July 2021

Karakter adalah sikap, sifat, tingkah laku seseorang yang sesuai dengan aturan atau norma yang berlaku di masyarakat. Seseorang akan diterima di kalangan masyarakat tertentu apabila ia hidup sesuai dengan norma yang berlaku di dalam masyarakat tersebut. Prinsip tersebut juga berlaku bagi orang Kristen. Orang Kristen yang telah menerima Yesus Kristus sebagai Tuhan dan Juruselamat secara pribadi, wajib meneladani hidup dan karakter serta ajaran Yesus Kristus dalam kehidupan sehari-hari. Karakter Kristus tidak serta merta ada di dalam diri seorang anak. Anak perlu dituntun, dibimbing oleh orang yang lebih dewasa yaitu orangtua.
Orangtua diberi tanggung jawab oleh TUHAN untuk mendidik, mengajarkan dan membentuk karakter anak-anaknya. Oleh karena itu, pembentukan karakter anak merupakan hal yang sangat penting untuk diperhatikan oleh orangtua sejak dini sebab orangtua adalah pendidik pertama dalam pendidikan informal.
Metode penelitian yang digunakan adalah metode kualitatif lapangan dengan teknik observasi, wawancara dan dokumentasi. Hasil Penelitian membuktikan bahwa sebagian besar orangtua sudah menyadari perannya sehingga dapat menjalankan tanggung jawabnya dalam membentuk karakter anak. Sedangkan beberapa orangtua belum maksimal dalam membentuk karakter anak karena belum menyadari tanggung jawabnya tersebut.
Pengaruh Teknik Relaksasi Benson Terhadap Kualitas Tidur pada Lanjut Usia
Authors: Hidayat Rahmat , Amir Haeril
Published: July 2021

Benson Relaxation is a technique for reducing pain, overcoming sleep disorders and dealing with anxiety. The developmental stage of the elderly is characterized by the loss of a lot of body cells and a decrease in the metabolism of body cells which causes a decrease in body function and changes in body composition as well as a decrease in strength and health. One of the complaints that are felt related to sleep is difficulty sleeping, often waking up during the night and feeling unrefreshed wh en awakened from sleep.
Pengaruh Pelatihan Balut Bidai terhadap Pengetahuan Penatalaksanaan Fraktur pada Anggota PMR di SMK Kota Makassar
Authors: Ernasari Ernasari , Kaelan Cahyono , Nurdin Andi Armyn
Published: July 2021

Balut bidai training aims to minimize the impact that can occur so that every lay person can help if they find victims who have an accident.The research aimed to analyze to what extent the effect of the splint wrap training using the watching video method on the fracture management knowledge of the Youth Red Cross members. This was the qualitative research with the one group pretest posttest design method with the samples of 70 students of YRC members. The samples were selected using the non-probability sampling technique with the purposive sampling approach. The date were analyzed using T-Test. The research result indicates that there is no significant difference concerning the knowledge level between the simulation group and video group (? = 0.063), whereas on the skill level, there is the significant difference between the simulation group and video group (? = 0.000). Thus, it can be concluded that the training using the video method can improve the fracture management knowledge fester than the training using the simulation method, so that it is expected that the training using the video method can be utilized for almost all topics, and every cognitive, affective, psychomotoric and interpersonal domain.
Mepolizumab decreased the levels of serum galectin-10 and eosinophil cationic protein in asthma
Authors: Kobayashi Konomi , Nagase Hiroyuki , Sugimoto Naoya , Yamamoto Shiho , Tanaka Akihiko , Fukunaga Koichi , Atsuta Ryo , Tagaya Etsuko , Hojo Masayuki , Gon Yasuhiro
Published: July 2021

Background

Mepolizumab, a humanized antibody targeting interleukin-5, decreases the number of blood eosinophils and the frequency of exacerbation of severe asthma. Galectin-10 is a protein within the cytoplasm of eosinophils and constitutes Charcot-Leyden crystals, which promotes key features of asthma. However, the relationship between time kinetics and clinical response of eosinophil-derived molecules such as galectin-10 or eosinophil cationic protein (ECP) has not been precisely investigated.

Objective

This study aimed to clarify the precise time course of the levels of serum galectin-10 and ECP after mepolizumab treatment and to analyze the relationship between the levels of eosinophil-derived molecules and the clinical background or response to mepolizumab treatment.

Methods

This multicenter, prospective open-label study recruited 20 patients with severe eosinophilic asthma. Mepolizumab was administered every 4 weeks for 32 weeks and the levels of various biomarkers were serially analyzed.

Results

The serum galectin-10 and ECP significantly and rapidly decreased 4 weeks after initial administration of mepolizumab. In contrast, basophil count, fractional exhaled nitric oxide, and the serum total IgE level were unchanged during treatment. Asthma Control Questionnaire-5, Asthma Health Questionnaire-33, and Lund-Mackay scores significantly improved after mepolizumab treatment. Both high ECP and eosinophil count related to better response in forced expiratory volume in 1 second (FEV1) and measurable ECP level at 4 weeks after administration of mepolizumab related to the further improvement in FEV1 toward week 32. No significant difference in improvement in FEV1 was observed in galectin-10 high group. The level of ECP at baseline was significantly related to the higher prevalence of nasal polyp and Lund-Mackay score.

Conclusion

This study was the first to show that the levels of serum galectin-10 decreases after initial administration of mepolizumab. The significant relationship between serum ECP and better response in FEV1 suggested the potential role of serum ECP as a predictive biomarker for the efficacy of mepolizumab (UMIN000030466).
Clinical evaluation of rush immunotherapy using house dust mite allergen in Japanese asthmatics
Authors: Uchida Takahiro , Nakagome Kazuyuki , Iemura Hidetoshi , Naito Erika , Miyauchi Sachiko , Uchida Yoshitaka , Soma Tomoyuki , Nagata Makoto
Published: July 2021

Background

Allergen immunotherapy (AIT) is a specific treatment of administering clinically important allergens to patients who have allergic diseases. In Japan, the standardized house dust mite (HDM) allergen for subcutaneous immunotherapy (SCIT) was approved in 2015, and we then introduced rush-immunotherapy (rush-IT) using the standardized HDM allergen for HDM-sensitive asthmatics. However, little data are available on the safety and effectiveness of rush-HDM-IT, especially for Japanese asthmatics.

Objective

The objective of this study was to examine the safety and clinical effectiveness of rush-IT using the standardized HDM for HDM-sensitive Japanese asthmatics.

Methods

Thirteen HDM-sensitive asthmatics who received rush-HDM-IT and 12 HDM-sensitive asthmatic controls were enrolled. To evaluate the safety, the number of systemic reaction (SR) events, including anaphylaxis, was assessed. To evaluate the effectiveness, changes in the treatment step, dose of inhaled corticosteroid, and asthma control after rush-HDM-IT and the subsequent maintenance SCIT were assessed. Changes in the HDM-induced production of type 2 cytokines from peripheral blood mononuclear cells were also evaluated.

Results

Among the 12 patients who received rush-IT, 4 (30.7%) experienced a SR and 3 (23.1%) experienced anaphylaxis. However, the anaphylaxis was not severe (grade 3) in all cases, and they recovered in a short time. The treatment step of asthma was better and the dose of inhaled corticosteroid was lower in the rush-HDM-IT group than in the control group. The HDM-induced production of both interleukin (IL)-5 and IL-13 from peripheral blood mononuclear cells was significantly lower in the rush-HDM-IT group than in the control group.

Conclusion

Rush-HDM-IT can be performed relatively safely in Japanese asthmatics. Furthermore, rush-HDM-IT and the subsequent maintenance SCIT provided clinical improvement in asthma patients, and was accompanied by the suppression of HDM-specific Th2-mediated systemic immune responses.
Behavior of Spanish durum wheat genotypes against Zymoseptoria tritici: resistance and susceptibility
Authors: Porras Rafael , Pérez-de-Luque Alejandro , Sillero Josefina C. , Miguel-Rojas Cristina
Published: July 2021

Aim of study: Septoria tritici blotch (STB), caused by the fungus Zymoseptoria tritici, is one of the most important wheat diseases worldwide, affecting both bread and durum wheat. The lack of knowledge about the interaction of durum wheat with Z. tritici, together with limited resources of resistant durum wheat material, have both led to a rising threat for durum wheat cultivation, particularly in the Mediterranean Basin. In Spain, STB has increased its incidence in the last few years, leading to higher costs of fungicide applications to control the disease. Therefore, identification of new sources of resistance through wheat breeding stands out as an efficient method of facing STB.Area of study: The experimental study was conducted in growth chambers at the IFAPA facilities in Córdoba (Spain).Material and methods: The percentage of necrotic leaf area, the disease severity, and the pycnidium development through image analysis were evaluated from 48 durum wheat Spanish accessions (breeding lines and commercial cultivars) in growth chambers against an isolate of Z. tritici from Córdoba.Main results: Two breeding lines and six commercial cultivars showed resistant responses by limiting STB development through the leaf or its reproduction ability, while the other 40 accessions presented a susceptible response.Research highlights: Provided these resources of resistance in Spanish durum wheat genotypes, future breeding programs could be developed, incorporating both agronomic traits and resistance to STB.
De raadsheer-commissaris in het enquêterecht
Authors: Soerjatin E.M. , Kruse C.L.
Published: July 2021

De raadsheer-commissaris in het enquêterecht

De raadsheer-commissaris houdt toezicht op de procesmatige kant van het onderzoek door middel van het geven van aanwijzingen aan de onderzoeker respectievelijk het geven van bevelen aan de rechtspersoon of belanghebbenden. Sinds de introductie in 2013 is de raadsheer-commissaris minstens twintig keer in actie gekomen in vijftien verschillende enquêtes.
Digital Technology Use during the COVID-19 Pandemic and Its Relations to Sleep Quality and Life Satisfaction in Children and Parents
Authors: Kotrla Topić Marina , Varga Vanesa , Jelovčić Sara
Published: July 2021

This research aimed to examine digital technology (DT) use, sleep quality (SQ), and the correlations between these variables in children and parents, in Croatia during the lockdown. Furthermore, it aimed to determine parental life satisfaction (LS) and its relation to DT use. In an online questionnaire, 281 parents of children (3 to 14 years old) provided information about the duration of DT activities throughout the pandemic, compared to the time before the pandemic, the time spent using digital devices in a typical day, and SQ for themselves and their children, as well as the estimates of personal LS. The results show that the relationship between DT use and SQ during the lockdown differs between parents and children. More time spent using DT devices is not related to SQ in parents, and more time spent on smartphones is positively associated with parents' LS. In children, the prolonged use of smartphones for leisure is negatively linked to SQ. These results call for caution in allowing children longer screen time.
Life Habits of Children and Young People during Social Isolation Caused by the COVID-19 Pandemic
Authors: Ćurković Natalija , Lukačin Lorelaj , Katavić Ivana
Published: July 2021

The aim of the study was to examine the habits of high school and primary school students related to diet and physical activity before and after the period of social isolation. Furthermore, the relationship between parents' attitudes about the importance of physical activity and their children's motivation to engage in it was examined. The online questionnaire was completed by 25,274 parents of primary school students and 5,169 high school graduates from the Republic of Croatia. The results show a trend of decreasing motivation to engage in physical activities, as well as an increase in the number of meals consumed per day among all students. Furthermore, there was a low positive correlation between parental attitudes and the motivation of their children to engage in physical activity both before and during social isolation. In conclusion, this large-scale study showed that due to social isolation there was a significant decrease in the motivation for physical activity and an increase in the number of daily meals.
Don’t trust the modern environmental epidemiologists!
Authors: Ulmer H.-V.
Published: July 2021

Air pollution is responsible for more than 400.000 premature deaths/year in Europe – so German newspapers and other media complained at 9 September 2020, refering to the European Environment Agency [1]. If you ask the scientic base of this statement with severe political and economic consequences, you will find numerous studies since many years. Nearly all these studies describe “associations”, “interactions” ore model calculations regarding air pollution and regional incidences, but for the author not a convincing proof for causality. Correlations don’t proof causal interactions, they include a hight risk of stork-
-statistics. A similar case exist in the risk-level of NOx, decided by the EU as 40 μg/m3 (mean of year) to “protect human health and the environment” [2]. In Germany the MAK-value amounts to 950 μg/m3 (i.e. 23 times higher) for longlife expositions at workplaces, based on thorough toxicologic studies.
There is a high interest of environmental politicans to propagate such “bad news” (400.000 deaths/year in Europe) and the public media like such news. So the author, claming about this scenario, got the followimg answer from the German ministry of health (23 September 2020 09:02): Usual toxikologic and clinical studies, often used to confirm a causality, are not suitable answering such questiions (with reference to Bradfort Hill criteria [3]).
Why biomatical epidemiologists work on year after year for such research? Perhaps political and public attention garantee good chances for successful third-party-funding and acquisition of impact scores, very favorable in the actual scientific business.
So the author is interested to discuss these considerations for getting new insights.
Performance of a new recuperative Heat and Moisture Exchange Mask
Authors: Wehrle Mario P. , Küpper Thomas , Muth Claus-M.
Published: July 2021

Aim of the study: The purpose of this work is to show the possibility to use a recuperative design of a heat and moisture exchange face mask (HME). Such HME are used as cold weather face masks for Arctic expeditions and conditioning of air for long-term intubated patients. Common regenerative HME have the disadvantage of increasing airway resistance and airway volume (dead space). In recuperative devices, the separation of inspired and expired airflow could reduce dead space and resistance.
Materials and methods: Prototype HMEs were built using two concentric ducts of aluminium or cotton. A valve ensures that expired and inspired air are led through either the inner or the outer tube. The inner tube’s wall transmits heat and water. The HMEs were tested in a simulated Arctic environment using a breathing simulator and characterized in terms of heat and moisture exchange efficiency. The new design was also tested at room temperature in order to simulate the conditions of long-term intubation. To compare the results, the relative difference in temperature (Performance Coefficient PC) between the expired and the inspired air was calculated.
Results: During the experiments, the ambient temperature was −37°C and therefore the absolute water content was about zero. The recuperative HME conditioned the air to 21°C and 10.7 mg/l water (61% relative humidity), giving a PC of 82%. At room temperature the recuperative mask showed a PC of 62%.
Conclusion: The recuperative HME shows great potential. It might be of use in clinical conditions and Arctic expeditions.
Analizy bezpieczeństwa konstrukcji budowlanych ulegających degradacji na podłożach górniczych. Część 1. Klasyczne postępowanie inżynierskie
Authors: Fedorowicz Jan
Published: July 2021

Oprócz analiz szczegółowych
w praktyce inżynierskiej zachodzi często potrzeba ustalenia w krótkim czasie odporności zabudowy całych zespołów wiejskich lub miejskich (dzielnic i osiedli) na wpływy eksploatacji – bieżącej, planowanej lub deformacji pogórniczych. W tym celu najczęściej wykorzystuje się metodę najszybszą – tak zwaną metodę punktową. Ograniczenia tej metody wykluczają jednak budowle nietypowe np. halowe, w złym stanie technicznym itp. Dla przypadków takich, wymagających szczegółowej i indywidualnej analizy, opracowano przedstawioną analityczną metodę parametryczną [1]. W artykule opisano przypadek analizy rzeczywistego, nietypowego obiektu inżynierskiego, którego bezpieczne użytkowanie zagrożone zostało przez nadmierną deformację podłoża gruntowego, pokazując drogę postępowania inżynierskiego przy ocenie bezpieczeństwa tego obiektu.
Analiza usterek w wybranych budynkach mieszkalnych
Authors: Hoła Bożena , Pochybełko Karol
Published: July 2021

W artykule przeprowadzono analizę ilościową usterek występujących
w 8 budynkach mieszkalnych wybudowanych w latach 2017–2020. Na podstawie bazy danych 9362 zgłoszonych defektów budowlanych określono typy usterek najczęściej i najrzadziej występujących w lokalach mieszkalnych, a także częściach wspólnych. Przedstawiono zestawienie typów usterek ze względu na ich udział procentowy we wszystkich stwierdzonych defektach. Ponadto określono średnią ilość usterek w przeliczeniu na każdy lokal, a także średnią ilość usterek na każdy metr kwadratowy powierzchni użytkowej wraz z wnioskami. Wskazano również kierunki dalszych badań.
Dostępność zajezdni a plany i możliwości rozbudowy sieci tramwajowych
w świetle wrocławskich uwarunkowań
Authors: Makuch Jacek
Published: July 2021

W artykule odniesiono się do problemu, jakim jest brak zapewnienia nieprzerwanej dostępności sieci tras tramwajowych z obsługujących je zajezdni w przypadku niekorzystnego ich umiejscowienia w tejże sieci Rozpoznano przyczyny zjawiska likwidacji starych i powstawania nowych zajezdni tramwajowych. Zwrócono uwagę na różnice obecnie występującego umiejscowienia zajezdni funkcjonujących od wielu lat w stosunku do nowo powstających. Przeanalizowano ukształtowanie wrocławskiej sieci tramwajowej zarówno pod względem przebiegu tras, jak i lokalizacji zajezdni, w odniesieniu do infrastruktury istniejącej oraz planowanej. Podano przykłady braku okresowej dostępności wrocławskich zajezdni spowodowanej remontami torowisk. Zaproponowano uzupełnienie planów rozbudowy wrocławskiej sieci tramwajowej o nowe odcinki tras w celu uzyskania poprawy dostępności zajezdni zarówno istniejących, jak i planowanych. Wykazano szereg innych zalet wynikających z ujęcia w planach proponowanych w artykule nowych połączeń.
Projektowanie ukierunkowane na prosumpcję. Koncepcja domu do samodzielnego montażu
Authors: Idem Robert , Kempa Stanisław , Zielonko-Jung Katarzyna
Published: July 2021

Idea prosumpcji polega na włączaniu przyszłego użytkownika w proces powstawania dobra, z którego będzie w przyszłości korzystał. Zjawisko to pojawia się w architekturze i budownictwie w niewielkim zakresie, jednak dynamiczny rozwój technologii w coraz większym stopniu tworzy możliwości dla takiego podejścia. W artykule poruszono ideę prosumpcji w odniesieniu do procesu wznoszenia budynku. Przedstawiono kierunki, które można wyodrębnić na podstawie analizy podejmowanych współcześnie prób samodzielnego budowania. Na ich tle zaprezentowano autorską koncepcję systemu pozwalającego wznosić obiekty o niewielkiej skali samodzielnie przez osoby nieposiadające wiedzy w zakresie budownictwa. Koncepcja powstała w ramach poszukiwań badawczych typu research by design. Studium obejmuje ogólną koncepcję systemu oraz projekt jego wykorzystania przy wzniesieniu domu mieszkalnego rekreacyjnego o powierzchni 35 m2. Projekt pozwolił autorom na wstępną ocenę jego możliwości i ograniczeń oraz przewidywania, w jaki sposób można je rozwijać.
Peristaltic-Ciliary Flow of A Casson Fluid through An Inclined Tube
Authors: Ramachandran Saravana , Vajravelu Kuppalapalle , Prasad K.V. , Sreenadh S.
Published: July 2021

The paper is concerned with the peristaltic-ciliary transport of a viscoplastic fluid (Casson fluid) through an inclined cylindrical tube. The peristalsis-cilia induced motion is analysed in the moving frame of reference under the lubrication approximations. Solutions to the flow characteristics petering to yielded and unyielded regions are obtained. The effects of various physical parameters on the axial velocity, the pumping characteristics, the pressure rise, and the frictional force over one wavelength, along with the trapping phenomenon are presented through graphs. Further, the peristaltic flow and peristaltic-ciliary flow results are compared. It is noticed that the axial velocity and the size of trapping bolus in the unplug flow region decrease with an increase in the yield stress. In addition, the axial velocity and the axial pressure gradient in the peristaltic-ciliary pumping are higher than those in the peristaltic pumping.
2016 Geneva Declaration on Person Centered Integrated Care through the Life Course
Authors: College of Person Centered Medicine International
Published: July 2021

2016 Geneva Declaration on  Person Centered Integrated Care through the Life Course
Person-centered Health Coaching in a Scottish Prison Population: Findings at Training Completion
Authors: Cinar Ayse Basak
Published: July 2021

Introduction: People in Scottish prisons (PSP) have poorer health than the general population. The promotion of health and wellbeing in prisons is a central aim of Scottish Government policy. Objective: This study was aimed at designing, implementing and evaluating person-centered health coaching (HC) training to improve PSP´s health and related psycho-social skills.Methods: PSP were trained as health coaches, as part of National Health Service (NHS) Scotland’s oral health prison intervention, termed Mouth Matters (MMs). A unit of MM involving HC is named PEPSCOT. Here PSP were trained by a qualified coach over a three-month period to become health coaches; 8, 4 and 4 whole day training took place respectively during the first, second, third month of training. Self-assessment questionnaires and diaries were used before, during and after the HC training to test the extent to which HC works to improve PSP´s health and related psycho-social variables. The outcome measures analyzed in the present study were self-assessed health and behaviors, self-efficacy, self-esteem, depression, and usefulness of the program. Follow-up data will be collected in September 2016 for further assessment of the impact of HC.Results: The baseline data showed that the majority of the participants were from low socio-economic status, and reported a moderate level of health. Data showed later that when compared with baseline levels two of the outcome variables (self-esteem and self-efficacy) improved significantly (p<0.001) at the mid-training point, and that all four outcome variables (also including self-assessed health and depression) improved significantly (at least p<0.05) at the completion of training. Participants’ positive evaluation of the training was significantly correlated with improved health and psychological measures (p<0.05).Conclusions: Health Coaching training represents a new person-centered approach that appears to enhance self-assessed health, mood, self-esteem and self-efficacy among prisoners in Scotland, and also to enable transitions from negative to positive concerning beliefs, values, and self-evaluations. There is however a need for further studies at a larger scale.
Patient-Centered Care and People-Centered Health Systems in Sub-Saharan Africa: Why So Little of Something So Badly Needed?
Authors: De Man Jeroen , Mayega Roy William , Sarkar Nandini , Waweru Evelyn , Leys Mart , Van Olmen Josefien , Criel Bart
Published: July 2021

Patient–centered care (PCC) is increasingly recognized as a key dimension of quality healthcare, but unfortunately remains poorly implemented in practice. This paper explores the current state of PCC in sub-Saharan Africa and potential barriers to its implementation, with a focus on public first line health services. We develop an analytical framework based on expert knowledge, field experience, and a conceptual literature review. Factors contributing to the (lack of) implementation of PCC are structured in three distinct but interacting layers. The first layer encompasses factors that influence and shape the performance of providers.  The training of health workers is key in that respect. Training models remain dominated by a biomedical perspective, with little attention for psychosocial dimensions of the illness experience. The second layer of determinants relates to the structural and organizational features of the health system. The emphasis in many African health care systems on specific programmatic outputs, and the subsequent pressure this creates on health workers,  jeopardize the delivery of PCC. The third layer is related to the broader socioeconomic environment in which health workers operate. Noteworthy is the gap between the “official” norms in the public sector and the actual behavior of providers. We then propose  possible avenues for change for each of these three layers. We conclude by arguing the need for further fine-tuning of the framework outlined in this paper, investing in the contextual validation of measurement tools for PCC, and testing solutions in a participatory action research framework.
Person-Centered Medicine: An Existential Outline beyond the Biopsychosocial Model
Authors: Ruiz-Moral Roger
Published: July 2021

Starting from the idea that “medical problems” are always “problems of living” that reflect the existence of a “vital dimension” that is different from the biological, psychological and sociocultural dimensions, this article describes central features of this dimension. From this viewpoint, its inescapable importance in the clinical act is highlighted, an importance that shapes the tasks that are inherent to it – diagnosis and decision making – but also the very process of the doctor-patient relationship. It is argued that “the subjective truth” implicit in the “vital dimension” (in the “existential self”) can only be approached through reflection and interpretation in the context of a dialogue between the professional and the patient/family with the objective of deciding on the action(s) that can better lead to reaching some concrete wishes or desires (values), that in turn require the participants to take on obligations and responsibilities. This relational perspective defines the “person centered” clinical approach as a practice based on dialogue, importantly involving deliberation and collaboration (“collaborative deliberation”). In this dialogue, the emotions, integral elements of the life dimension of its protagonists, play a decisive role both in attaining clinical effectiveness and in building and maintaining the relational process (encouraging or reducing trust) that is indispensable in a clinical activity that is an eminently moral act. Finally, the main challenges that doctors face when implementing this clinical focus and the educational challenges it entails are outlined.
Measurement of Liability to Addiction: Dimensional Approaches
Authors: Vanyukov Michael , Cornelius Marie , De Genna Natacha , Reynolds Maureen , Kirillova Galina , Maher Brion , Kirisci Levent
Published: July 2021

Background:   Biomedical research and its applications, particularly in complex disorders, have historically been guided by the group-defined disease-oriented perspective rather than a person-centered health-oriented approach. This has been an obstacle to the development of prevention and treatment methods. There is thus a need to redirect studies to augment diagnostic systems with individualized phenotypic measurement.  Objectives:   The goal of this paper is to develop a pragmatic dimensional perspective on the complex traits underlying probabilities of disorder development.  Method: Selective literature review of the foundation and methods for measuring liabilities to complex disorders and its aspects, and consultation on practical approaches.  Results:  The paper presents novel applications of the person-centered principle in psychiatric research, particularly addiction science, which can be used in any translation-oriented etiological health studies. These applications focus on the quantitative measurement of the individual phenotype along the full scale of the latent trait of liability and its understudied aspect, resistance to the disorder. Conclusions:  The novel perspective and methodology we introduce facilitate a shift from the group-defined “disease” to the person-centered individual liability phenotype, and from the factors that lead to and determine risk for disease to the mechanisms that result in health and determine resistance to a disorder.
Introduction to Art and Literature as Components of Person-Centered Care
Authors: Sukhanova Ekaterina
Published: July 2021

The article brings the attention of mental health professionals to the theoretical framework underpinning the contemporary understanding of the dynamics of psychiatric art. Using the semiotics approach to art production and perception, the article makes the connection between the dialogical mechanisms of art and the potential uses of art to counteract stigma, including self-stigmatization. Creative works by patients have long been acknowledged a key source of information in the clinical diagnostic process. Furthermore, because all artistic activity is a communicative act, working with patient art aids the clinician to gain a better understanding of the preserved aspects of a patients’ personality, beyond the pathological syndromes, and build a better rapport, resulting in more successful therapeutic approaches. Gaining an insight into patient art allows the clinician to be more effective in planning specific medical and social rehabilitation strategies. At the community level, outsider art is a powerful tool in anti-stigma campaigns because the dialogic potential inherent in art is conducive to stopping the “vicious cycle” of stigmatization.
Functional Somatic Symptoms and Somatization: Person-centered Approach to Understanding their Relationships
Authors: Falcoff Ariel
Published: July 2021

Background: Despite the visible points of overlapping between the psychopathologic concepts of "somatization" and "somatoform disorders" with those of "functional symptoms" and "somatic syndromes" of general medicine, there is little literature which clarifies their relationships, making it difficult to formulate common grounds for work between psychiatry and the rest of medicine. Objectives: The purpose of this article is to review and critically analyze current knowledge on the subject, in search for conceptual links between different paradigms involving the underlying phenomena, proposing present and future lines of work according to the basic concepts of the Person Centered Medicine. Methodology: A wide ranging review and critical analysis of the literature on these subjects was conducted, trying to explore the relationship and integration of different paradigms according to the MCP framework and an outline of the author´s current research. Results: A need was found to establish transdisciplinary concepts which leave aside the particular visions of each paradigm, in search for links which may integrate different insights, considering the person as a whole. Therefore, it is essential to analyze carefully the phenomenon from various points of view to elucidate wider conceptualizations so as to reformulate this spectrum of phenomena from an integrative perspective. The possibility of the existence of a “general factor”, both present in the so-called “functional” disorder of general medicine, and in those that in psychopathology are grouped as somatization, is suggested. This general factor could be represented by certain personality dimensions and psychic representations encompassed by complex context variables. Conclusions: It would be valuable to continue with research of this phenomena structure as well as to look for strategies to benefit from the theoretical findings in the health care field, according to the proposals of Person Centered Medicine.
INTERNATIONAL PERSPECTIVES ON WELL-BEING AND BURNOUT WITHIN HEALTH SYSTEMS
Authors: Appleyard James
Published: July 2021

Objectives: To reflect on the present international culture of professional burnout

in health care systems and the need for a radical new approach with an increased

understanding of a person- and people-centered attitudes in the promotion of

training in wellbeing and the prevention and management of burnout among

physicians and health care professionals

Methods: A literature search worldwide was undertaken for significant research

papers on professional education related to burnout with particular reference to

both medical staff resilience and health care system factors.

Findings: Burnout among doctors is a global phenomenon. The incidence of

burnout reported in a selection of studies among pediatric residents and staff are

25% in Argentina, 37% in the United Kingdom, and 70% in Saudi Arabia. In a

national survey in the United States where the overall rate was 59% burned out

residents reported significantly increased stress, poorer mental health, and

decreased empathy, mindfulness, resilience, self-compassion, and confidence in

providing compassionate care Three levels of change that should be the focus of

training in prevention, health promotion, and stress reduction awareness have been

recommended to reduce the risk of burnout: (1) modifying the organizational

structure and work processes; (2) improving the fit between the organization and

the individual doctor through professional development programs so that better

adaption to the work environment occurs; and (3) individual-level actions to reduce

stress and poor health symptoms through effective coping and promoting healthy

behavior.

Discussion: The history of burnout shows important links with increased work

complexity. Narrow training interventions such as debriefing after an adverse

clinical event have not been found effective. A more comprehensive personcentered

approach with a variety of measurable interventions has resulted in a

reduction of 50% in the pediatric faculty in one study. A person- and

people-centered cybernetic approach is needed with six standards are to establish

and sustain a healthy work environment (1) authentic leadership (2) meaningful

recognition, (3) skilled communication, (4) true collaboration, (5) effective

decision making, and (6) appropriate staffing.

Conclusion: With such high levels of burnout, health systems worldwide can be

viewed as failing their populations on a grand scale. Only an organizational

paradigm change to a person- and people cybernetic centered system that

incorporates complexity is adaptive and integrative will a health system be

effective in preventing and ameliorating the effects of burnout and reduce the

increasingly unaffordable misuse of human resources.
7TH INTERNATIONAL CONGRESS OF PERSON CENTERED MEDICINE
Authors: Mezzich Juan
Published: July 2021

Congress Presidents: Yoshitake Yokokura, President of JMA and Jon Snaedal,

President of ICPCM

Organizing Committee: International College of Person Centered Medicine,

ICPCM: Jon Snaedal (President,), Juan E. Mezzich (Secretary General), Jim

Appleyard (Board Advisor), Michel Botbol (Board Member), Tesfamicael

Ghebrehiwet (Board Member), Helen Millar (Board Member), Ihsan Salloum

(Board Member), Werdie Van Staden (Board Member), and Japan Medical

Association.
EstimaODE: Apoio a Estimativas de Tamanho e Esforço no Ambiente de Desenvolvimento de Software ODE
Authors: de Carvalho Victorio A. , Arantes Lucas O. , Falbo Ricardo de Almeida
Published: July 2021

Estimar é uma das tarefas mais difíceis de se realizar em um processo de software. Apesar de não ser uma ciência exata, há técnicas muito úteis para apoiar a realização de estimativas, sendo que estimativas acuradas geralmente são conseguidas quando se utiliza mais de uma delas e seus resultados são comparados e ajustados. Além disso, dados históricos são igualmente importantes. Neste contexto, gerentes de projeto necessitam de ferramentas para apoiá-los. Este artigo apresenta EstimaODE, uma ferramenta que apóia a realização de estimativas. EstimaODE está integrada ao ambiente de desenvolvimento de software ODE e utiliza sua infra-estrutura flexível para computar similaridade entre itens.
RiskFree – Uma Ferramenta de Gerenciamento de Riscos Baseada no PMBOK e Aderente ao CMMI
Authors: Knob Flávio , Silveira Filipi , Orth Afonso Inácio , Prikladnicki Rafael
Published: July 2021

Neste artigo é apresentada a ferramenta RiskFree, uma ferramenta desenvolvida para auxiliar as equipes de projetos de desenvolvimento de software a gerenciarem riscos em seus projetos. O enfoque principal do artigo é apresentar como a ferramenta está baseada nas boas práticas do PMBOK e aderente à área de processo de gerência de riscos do modelo CMMI. Também serão apresentadas algumas propostas de evoluções para a ferramenta.