bluuebunny/crossref_metadata_2025 huggingface dataset:
Spontaneous pneumomediastinum and tracheal injury: An extraordinary case report in an adult
Authors: Ibrahim Fadzillah , Yazid Mohd Boniami , Siong Lee Chee , Amran Dora Natasha
Published: March 2024

Spontaneous pneumomediastinum (SPM) associated with subcutaneous emphysema and tracheal injury following persistent vomiting is rare. Here, we report a case of a young adult who presented to the emergency and trauma department with severe vomiting and abdominal pain, persisting for four days, and denied any symptoms of respiratory distress. Physical examination revealed mild dehydration and abdominal tenderness. A chest X-ray indicated subcutaneous emphysema and pneumomediastinum. A subsequent computed tomography (CT) scan confirmed a tracheal tear, pneumomediastinum, and emphysema. The patient received conservative management, including fluids, adequate analgesia, and antibiotics. Spontaneous cases are often linked to forceful coughing. Diagnosis primarily relies on imaging, mainly CT scans, while bronchoscopy aids in assessing tracheal tears. Treatment typically involves conservative measures like observation, pain management, and antibiotics. The patient was managed conservatively with antibiotics and supportive care in this case. SPM with stable conditions typically respond favorably to conservative treatment, and complete resolution can be anticipated within two days to one week.
Effect of vitamin D on salivary cathelicidin in kindergarten children with dental caries
Authors: Al-Ghurabi Batool Hassan , Aldhaher Zainab Abduljabbar , kareem Mustafa Wathiq Abdul , Abd Suha Talal , Abdullah Wasan lafta , Abbas Ahmed Abdulhassan , Abbas Maha Jamal
Published: March 2024

Background: Dental caries is a heterogeneous microbial infection affecting the mineralized dental tissues and characterized by a gradual demineralization process. Vitamin D aids in the immunological response to oral infections, and its insufficiency can impact the patient’s general and dental health. Small cationic peptides known as cathelicidins are essential for developing innate immune systems. This study aimed to investigate the impact of vitamin D on the innate immune response by assessing the levels of cathelicidin in children with tooth decay.

Subjects and Methods: This study included 60 children aged 4-5 years, with 30 children having caries and 30 without caries. Oral examinations were conducted and scored using the dmfs index. Saliva samples were collected from all subjects, and ELISA was employed to determine vitamin D and cathelicidin levels.

Results: The current findings revealed that salivary levels of cathelicidin and vitamin D were significantly lower (P < 0.01) in children affected by caries than caries-free children. The results also showed a significant decrease (P < 0.01) in cathelicidin levels compared to the vitamin D sufficient group.

Conclusions: The study concludes that children with caries and vitamin D deficiency exhibit low levels of cathelicidin. The observed link between vitamin D deficiency and caries suggests that vitamin D contributes to the synthesis of cathelicidin.
Successful medical management of a pituitary macroadenoma with features of resistant acromegaly and hyperprolactinemia using pasireotide
Authors: Baagar Khaled Ahmed , Sadiq Amna , Khan Adeel Ahmad , Dabbous Zeinab , Rohani Zaina
Published: March 2024

Background: The somatostatin analog, pasireotide, is used for the treatment of acromegaly after the failure of surgery and/or first-line medical treatment.

Case Presentation: A 48-year-old male reported that during a workup for obesity in his home country, hyperprolactinemia was diagnosed and a 3.5 × 3.5 cm pituitary macroadenoma was identified on pituitary MRI. He received cabergoline for 6 months; then he was lost to follow-up. He presented at our Endocrine clinic 2 years later for treatment of obesity (BMI 49.5 kg/m2). Biochemical workup revealed that in addition to hyperprolactinemia (7,237 [normal: 85–323 mIU/L), he had acromegaly, evident by elevated insulin-like growth factor 1 (IGF-1) level (450 [normal: 88–210 µg/L]), and a positive growth hormone suppression test, secondary hypothyroidism, and secondary hypogonadism. Pituitary MRI showed that the adenoma encased parts of the left and right internal carotid arteries and encroached on the optic chiasm. Surgical excision was therefore not feasible. He was treated with cabergoline and later, long-acting release (LAR) octreotide. Prolactin levels were reduced with cabergoline, but IGF-1 levels did not respond to octreotide, and it was discontinued. The patient abandoned radiotherapy after two sessions. He was started on LAR pasireotide 40 mg every 4 weeks and continued on cabergoline 0.5 mg per week. His biochemical response was dramatic, with a near normalization of IGF-1 levels in 3 months. After 6 months from starting pasireotide, we increased cabergoline dose from 0.5 mg/week to 3 mg/week. Three months later, IGF-1 level was normalized. The patient developed type 2 diabetes as a side effect of pasireotide; however, this was well-controlled with medications.

Conclusions: The case suggests that pasireotide can provide marked biochemical improvement in acromegaly after the failure of both cabergoline monotherapy and cabergoline plus octreotide. This further confirms a potentially efficacious treatment regimen in treatment-resistant acromegaly with hyperprolactinemia.
Effects of different types of dried fruit on sensory and texture properties of white cheese
Authors: Tarakçı Zekai , Yolaşan Murat
Published: March 2024

In the study, five kinds of white cheese produced, one of which was a control sample (CC). According to the amount of curd used in the production of cheese, black mulberry (C1), blackberry (C2), black grape (C3) and raspberry (C4) dried fruit added to the curd at a rate of 2%. The cheeses packed with a vacuum packaging machine and left to ripening for 90 days at 7±1°C. During the ripening period (3rd, 30th, 60th, 90th days) samples were taken from cheeses, sensory analyses were performed, and textural parameters including resilience, hardness, springiness, gumminess, cohesiveness, adhesiveness, and chewiness were determined using texture profile analyses (TPA). It was observed that neither cohesiveness, adhesiveness and springiness parameters of texture profile differed in terms of cheese type, nor important statistical difference was identified (p˃0.05), differences regarding the ripening process found out though (p<0.05).
Relationships between anthocyanin content and some pomological and colour characteristics of black mulberry (Morus nigra) fruit
Authors: Öcalan Osman Nuri , Saraçoğlu Onur
Published: March 2024

The analytical method used to determine the total monomeric anthocyanin content of fruits is costly and labour intensive. Researchers are endeavouring to develop prediction models to determine anthocyanin content in a simpler and more accurate way. The aim of this study was to investigate whether there is a relationship between anthocyanin and some fruit characteristics (width, length, weight, L*, a*, b*, chroma, hue) in black mulberry (Morus nigra) fruit. With the outputs of the study, it is aimed to provide preliminary information for the models to be developed for anthocyanin estimation in future studies. The study material, black mulberry fruits, was collected from a single black mulberry tree in Kemalpaşa village of Tokat province in July 2022. Harvesting of the fruits continued for two weeks as raw, semi-ripe and ripe. A total of 586 fruits were individually evaluated and the weight, width, length, colour parameters (L*, a*, b*, chroma, and hue) and total monomeric anthocyanin contents of each fruit were determined. Then, Pearson correlation coefficients between the variables were determined. Stepwise regression analysis was used to find the appropriate model to explain the change in the dependent variable anthocyanin with independent variables (length, width, weight, L*, a*, b*, chroma, hue). After the multiple regression model was established, residual analysis was performed to see the outliers in the full model and to check the accuracy of the model. As a result of the study, it was observed that anthocyanin content could be predicted by colour parameters up to a certain maturity stage. This relationship was found to weaken at the ripeness stage when the fruit colour turns black.
Zero-Trust Architecture (ZTA): Designing an AI-Powered Cloud Security Framework for LLMs’ Black Box Problems
Authors: Dash Bibhu
Published: March 2024

Businesses are becoming more interested in developing and testing Large Language Models (LLMs) in their own settings to support decision-making and growth as a result of the rapid emergence of AI and cloud computing. Here’s the dilemma, though: to what extent do you believe these models and the data they were trained on? We don’t know the feature list of an LLM, which presents the first obstacle when discussing trust and the reasons why there should be zero trust. Although it may seem a bit extreme, this is accurate for two reasons. When it comes to GenAI models nowadays, the more multimodal and more capabilities they have, the better. This way of thinking is great for exploring and confirming if GenAI can address a business problem, but it’s a surefire way to run into trouble when attempting to put things into production in an organizational setting. An enterprise cybersecurity architecture known as a zero-trust architecture (ZTA) is built on the ideas of zero trust and is intended to stop data breaches, enhance privacy, and restrict internal lateral movement. This article discusses ZTA, its logical aspects, probable deployment scenarios, AI rules, threats and limitations in order to provide a detailed understanding of why enterprises must adapt a ZTA framework in a cloud-based environment for AI model deployment.
Enhancement of the Dissolution and Solubility of Canagliflozin Using Nanodispersion Systems
Authors: Jassem Nizar Awish , Abd Alhammid Shaimaa Nazar
Published: March 2024

Background: Self-nanomicellizing solid dispersion is a new formulation that combines the advantages of solid dispersion with nanomicelle methods to increase drug oral bioavailability. The technique employs an appropriate carrier to produce a solid dispersion that self-assembles into nanomicelles when in contact with gastrointestinal fluids, improving medication solubility and absorption. Objective: The study aims to develop a self-nanomicellizing solid dispersion of canagliflozin and compare it to non-nanomicellizing formulations. Methods: The solvent evaporation approach was chosen to create a solid dispersion system with soluplus and poloxamer 407 as carriers. Different canagliflozin-to-carrier ratios were investigated in order to develop nanomicellar systems with improved canagliflozin dissolving characteristics. Solid-state analysis was used to characterize the optimum self-nanomicellizing and non-self-nanomicellizing formulations. Results: The physicochemical tests revealed that canagliflozin's crystalline structure transitioned to an amorphous state in the solid dispersion system of both carriers, as evidenced by powder X-ray diffraction and differential scanning calorimetry. Particle size analysis reveals that only soluplus, in all ratios tested, produces a self-nanomicellizing solid dispersion of canagliflozin, whereas poloxamer 407 does not. Self-nanomicellizing systems incorporating Soluplus had a faster dissolving profile than pure drug and non-self-nanomicellizing formulas. Conclusions: Canagliflozin nanodispersion systems with Soluplus as a carrier may improve solubility, dissolving rate, and bioavailability.
Improvement of road infrastructure on the example of the Center-South transport corridor of the Akchatau-Akzhal section
Authors: Kiknadze Rima , Mukhamejanova Assel
Published: March 2024

The study investigates the enhancement of road infrastructure in the Center-South transport corridor of the Akchatau-Akzhal section, addressing the challenges posed by rapid road pavement deterioration due to increased traffic flow. By analyzing the natural and climatic conditions of the area, optimal concentrations of additives were determined to improve the properties of bitumen and asphalt concrete, with a focus on increasing strength and durability. Specifically, the addition of monoethanolamine to bitumen at a concentration of 0.08% led to notable improvements in key properties. The needle penetration depth at 25°C decreased from 80 to 71, indicating enhanced consistency. Moreover, the ring and ball softening point increased from 52 to 56, demonstrating increased resistance to temperature variations. Stretchability at 40 improved from 65 to 70, highlighting enhanced flexibility and durability. The study emphasizes the critical importance of quality construction and regular maintenance to ensure the durability and resilience of road networks to various factors. By utilizing innovative technologies and materials, such as modified binders with additives, the study showcases the potential to significantly enhance the performance, safety, and efficiency of road networks while reducing costs and environmental impact. The findings underscore the need for continued research and implementation of optimized solutions to improve road infrastructure sustainability and longevity.
Main problems in the operation of metal gas discharge pipes
Authors: Nuguzhinov Zmagul , Tokanov Daniyar , Rakhimov Ashat , Nurzhigit Almas
Published: March 2024

This paper considers the main problems of operation of metal gas discharge pipes on the example of research and survey work on the examination of building structures of the exhaust tower with three gas discharge trunks 180 m high, flue gas purification unit of the sintering shop of LLP "NDFZ" in Zhambyl region. Analysis of the actual technical condition, considered in this article exhaust tower with three gas discharge shafts, according to the results of the survey, its volume-planning and structural solutions, showed its generally unrepairable, due to the mass of characteristic critical and unacceptable damage to the load-bearing elements of the frame, physical fatigue of materials, significant corrosion wear of metal structures, which will require a significant amount of proposed repair and maintenance work to eliminate them. The conducted complex of researches has shown that the service life of chimneys built before the 1960s and after has practically expired. Repair or reconstruction of chimneys using previously mastered technologies and materials does not solve the issues of reliability improvement. Rational solutions to these problems are periodic technical expertise by highly specialized organizations and implementation on its basis of methods of overhaul of both gas-exhausting trunks and building structures and interface units, wide implementation of which will solve the problem of extending the life of chimneys.
A review of the current status of REBT and MBCT based treatment in the treatment of depression in Korea
Authors:   Korean Association of Rational Emotive and Cognitive Behavior Therapy, Byun Kyung-Hee
Published: March 2024

This study focuses on understanding the role and detailed treatment process of RBET (rational emotive behavior therapy), a second-generation theory in cognitive behavior therapy, and MBCT (mindfulness-based cognitive therapy), a third-generation theory in cognitive behavior theory. The research method compared and analyzed the two theories and domestic papers related to depression. The result of the study shows that RBET plays a fundamental role in treating depression by philosophically changing and modifying key beliefs that cause depression. The effectiveness of RBET has already been verified in many previous studies. The result of the study also shows that MBCT is used as maintenance therapy in cases where depression has improved. The process of MBCT is as follows: to notice signs of worsening or recurrence of symptoms; to get past negative emotions by focusing on the present; to learn to relate to the senses, emotions, and thoughts arising from within; and to switch to the “being mode” from cognitive defusion and the “doing mode”. In summary, RBET is effective as a quick and early treatment technique, and MBCT is effective as a maintenance treatment technique to prevent recurrence once depression has improved. This study is meaningful in maximizing the effectiveness of depression treatment by comparing the differences and commonalities between REBT and MBCT theories and clarifying the cooperative relationship.
Clinacanthus nutans leaf extract reduces pancreatic β-cell apoptosis by inhibiting JNK activation and modulating oxidative stress and inflammation in Streptozotocin-induced diabetic rats
Authors: Susanti Nurlaili , Mustika Arifa , Khotib Junaidi
Published: March 2024

Background:
Controlling apoptosis induced by oxidative stress in pancreatic β-cells provides promising strategies for preventing and treating diabetes. Clinacanthus nutans leaves possess bioactive constituents with potential antioxidant and anti-diabetic properties.
Aim:
This study aimed to investigate the molecular mechanisms by which C. nutans extract protects pancreatic β-cells from apoptotic damage in streptozotocin-induced diabetic rats.
Methods:
Diabetes was induced in male Wistar rats by intraperitoneal injection of 45 mg/kg streptozotocin, followed by 28 days of treatment with C. nutans leaf extract and Glibenclamide as the standard drug. At the end of the study, blood samples were collected to measure glucose levels, oxidative stress markers, and inflammation. Pancreatic tissue was stained immunohistochemically to detect c-Jun N-terminal kinase (JNK) and Caspase-3 expression.
Results:
The administration of C. nutans leaf extract to diabetic rats significantly reduced fasting blood glucose, malondialdehyde, and tumor necrosis factor-α levels, while concurrently enhancing the activity of superoxide dismutase. The immunohistochemical studies revealed a decrease in the expression of JNK and caspase-3 in the pancreatic islets of diabetic rats.
Conclusion:
C. nutans exhibits the potential to protect pancreatic β-cells from apoptosis by suppressing oxidative stress and inflammation.
تأثير تمرينات خاصة في تحسين بعض متغيرات التركيب الجسماني بعد عملية سحب الدهون للنساء بأعمار (30-45) سنة
Authors: اسراء شاكر محمود  , لمياء عبد الستار
Published: March 2024

انبثقت اهمية البحث من دور تأثير التمرينات خاصة في تحسين بعض متغيرات التركيب الجسماني بعد عمليات سحب الدهون للنساء بأعمار (30-45)سنة. اما مشكلة البحث تكمن في عدم اهتمام بعض النساء اللاتي خضعن لعمليات سحب الدهون لممارسة الرياضة والتمارين البدنية بآعتقادهن ان عمليات سحب الدهون هي الحل النهائي في التخلص من الشحوم والوزن الزائد ،حيث تلجأ الباحثتان الى استخدام تمرينات خاصة في تحسين التركيب الجسماني من اجل تناسق اجزاء الجسم بشكل طبيعي وشد الجسم والعضلات وتخلص من الوزن الزائد. ويهدف البحث الى التعرف على مدى تأثير تمرينات الخاصة في تحسين التركيب الجسماني بعد عمليات سحب الدهون للنساء بأعمار (30-45)سنة .اما فروض البحث فتكمن في وجود فروق معنوية بين الاختبار القبلي والبعدي في تحسين متغيرات التركيب الجسماني بعد عملية سحب الدهون لعينة البحث .واستخدمت الباحثتان المنهج التجريبي بعمل مقارنة بين الاختبار القبلي والبعدي للمجموعة بعد اداء الاختبارات وتطبيق التمرينات الخاصة على النساء ممن اجرين عمليات سحب الدهون والبالغ عددهم (6)مشتركات .واستنتجت الباحثتان ان تمرينات خاصة التي تم تطبيقها كان لها تاثير ايجابي في تحسين التركيب الجسماني والقياسات الجسمية بعد عمليات سحب الدهون للنساء بأعمار (30-45) سنة، وهذا ما يحقق احد اهداف التنمية المستدامة للامم المتحدة في العراق (الصحة الجيدة). وتوصي الباحثتان الى ضرورة استخدام التمرينات الخاصة التي تهدف الى اكتساب اللياقة الصحية واداء تمرينات تحسن المرونة والرشاقة من اجل الحفاظ على وزن الجسم والحصول على جسم متناسق .
How Do Proactive Personality and Internal Locus of Control Play a Role in the Links Between Career Adaptability and Job Search Behaviors of Job Seekers? A Two-Moderator Approach
Authors: Gerçek Merve , Özveren Cem Güney
Published: March 2024

The present labor market's rapid expansion has pressured individuals to enhance their employability and achieve professional success. Therefore, individuals need to be able to adapt and flourish in the face of unforeseen employment challenges, known as career adaptability. While previous studies have established the benefits of career adaptability in the job search process, there is a lack of understanding regarding the influence of personality characteristics on the relationship between career resources and job search behavior. This study investigates the combined moderating effects of proactive personality and internal locus of control on the link between career adaptability and job search behavior, drawing on career construction theory and planned job search behavior theory. The study sample comprises 308 individuals actively seeking employment in Istanbul and Kocaeli. SPSS AMOS was used for confirmatory factor analysis, and PROCESS Macro was used to examine moderator effects. The findings demonstrated a positive relationship between career adaptability, proactive personality, internal locus of control, and job-seeking behavior. Moreover, as predicted, the combined effect of proactive personality and internal locus of control moderates the relationship between career adaptability and job search behavior, suggesting the relationship is more robust when both traits are high. These findings are essential for researchers in the field of career and job search as well as for practitioners such as career counselors or training and development specialists.
SUSTAINABLE MATERIALS IN CONSTRUCTION
Authors:   ATMA MALIK INSTITUTE OF TECHNOLOGY AND RESEARCH, SHAHPUR., KADAM MISS. SONIYA
Published: March 2024

The construction industry is one of the largest exploiters of both renewable and non- renewable natural resources. It was inevitable that it would find itself at the centre of concerns regarding environmental impact. The process and operation of building construction consumes a great deal of materials throughout its service life cycle. The selection and use of sustainable building materials play an important role in the design and construction of green building. This chapter sets out to present an overview of sustainable building materials and their impacts on the environment. Materials used for the structure of buildings require properties of strength, whereas other parts, such as the envelope, are selected for their insulation or aesthetic properties. Comparisons become more complex when materials perform more than one function such as load-bearing walls that provide good thermal insulation. There is also a need to distinguish between finite resources and renewable resources when reviewing the sustainability of a material. Some materials, despite being non-renewable may be considered plentiful on earth; however, the consequences and impacts of mining them may be considered unacceptable. The effect of construction material selection will impact upon sustainability throughout the lifetime of both the material and that of the building itself. The need to maintain the building, replacing individual components, disposing of the old, and procuring the new will have environmental impact from cradle to grave. Keywords: Sustainable material, concrete, maintain, selection, renewable resource
A Study on the Changes of Gender Morality in China: Centered on the Male Experience in the "Love Letter" Incident (1900-1930)
Authors: ZHANG Yan , LI Yuhong
Published: March 2024

In the 20th century, China was an era of significant social changes, experiencing the impact of abolishing old and establishing new in politics, economy, culture, and other aspects. In terms of sexual morality, traditional sexual morality was criticized by Chinese youth and intellectuals, while new sexual morality was disseminated among young people. The love letter incident that occurred in such a social context is a representative event of young men and women actively breaking traditional sexual morality and constructing new sexual morality. This article takes two love letter events that occurred in China in the early 20th century and the 1920s as research objects, focusing on the experiences of young men in the love letter events. Using the method of seeking differences, it first clarifies the thoughts and expressions of young men on the issue of love in the love letter text. Secondly, it analyzes the views and debates of public power and social elites on the events in the love letter events, thereby revealing the end of the old sexual morality and the development of new sexual morality in modern China. In the two love letter events, the content of the young man's love letters both demonstrated his longing for new sexual morality. Qu Jiang faced criticism, while Qiu Gongyi received sympathy. The different experiences of the male protagonist in the two love letter events reflect the progress of China's modernization process in terms of neutral moral concepts.
Potential PD-1 inhibitor immune dysregulation as a risk factor for Listeria monocytogenes bacteremia and meningitis
Authors:   Rush University Medical Center, Au Cherry , Er Mehmet , Lin Michael , Williams Brett
Published: March 2024

As immune checkpoint inhibitor (ICI) therapy becomes increasingly popular for the treatment of cancer, there is a growing body of literature on opportunistic infections associated with ICI therapy. Pembrolizumab binds specifically to the PD-1 receptor on T cells, preventing PD-1’s interaction with PD-L1 and PD-L2. This blockade interrupts the inhibitory signal and restores a T cell’s ability to recognize and attack tumor cells. We present a case of invasive Listeria infection associated with ICI therapy. The case also suggests treating patients undergoing active ICI therapy as potential immunocompromised hosts due to possible immune dysregulation related to ICI therapy.
FARMERS’ WIVES’ ASSOCIATION IN THE CONCEPT OF NEO-ENDOGENOUS DEVELOPMENT OF RURAL AREAS
Authors: Parzonko Anna Justyna , Sieczko Anna
Published: March 2024

Farmers’ Wives’ Association are the most popular form of women’s self-organization in rural areas with a long tradition dating back to the 19th century. The aim of the presented research was to seek an answer to the question of what motives guide people joining Farmers’ Wives’ Associations and what factors influence their functioning. The concept of neo-endogenous development, based on the use of endogenous (local) resources to acquire exogenous (external) resources, is presented. Neo-endogenous mechanisms allow for better identification of development needs and targeted involvement of external resources in meeting them. The basis of these mechanisms is local social capital concentrated, for example, in the village housewives’ circles. A survey was conducted using a custom survey questionnaire, created on the ProfiTest platform. 52 Associations correctly completed the questionnaire. For today’s Farmers’ Wives’ Association, the most important activities are those aimed at the development of localities and the cultivation of local and regional culture. In the aspect of neo-endogenous development, it is important to emphasize the influence of both endogenous and exogenous (the possibility of raising funds) factors on the significant increase in the interest of local communities in this form of cooperation.
SPATIAL DIFFERENTIATION OF THE EMISSIVITY OF AGRICULTURE IN EUROPE
Authors: Rawa Grzegorz , Pietrzykowski Robert
Published: March 2024

This paper presents the results of a study aimed at determining the spatial variation in the carbon intensity of the agricultural sector in Europe. The analyses used the volume of greenhouse gas emissions from the agricultural sector (in 2020), expressed in carbon dioxide equivalent, calculated according to the IPCC methodology for 31 European countries. To reduce variance and the impact of country size on emissions, three emissivity factors were calculated, depending on: agricultural area, value of goods produced by agriculture and population. To verify the relationship between emissivity and location, the Moran autocorrelation coefficient was used, calculated on a modified weighting matrix that, in addition to the criterion of a common border, takes into account the similarity of objects in terms of the values of diagnostic variables (similarity determined using cluster analysis) – in this case indicators describing the emissivity of the agricultural sector. The study showed that there was no reason to reject the hypothesis of a random distribution of objects in space with respect to the values of the indicators included in the study. It can therefore be concluded that there are some similarities in the emissivity from the different European economies, as evidenced by the cluster analysis results, while there is no spatial correlation.
The Responsibility of Natural Resources Conservation Center in Preventing Encroachment of Conservation Forest Areas in East Nusa Tenggara
Authors: Mau Ellon Belwan Cornelius , Naatonis Mathelda
Published: March 2024

This research aims to examine the relationship between the increase in encroachment on conservation forests and the classification of forests based on their ownership status, as well as assess the East Nusa Tenggara BBKSDA's responsibility in addressing conservation forest encroachment. This research uses an empirical legal research method. All collected data is then qualitatively analyzed to describe the problem and answer the research objectives. The results show that land ownership claims, boundary disputes, and a lack of community understanding regarding conservation forest status are the primary causes of encroachment. Although the East Nusa Tenggara BBKSDA has taken various proactive steps to address conservation forest encroachment, the issue has not yet been fundamentally resolved. Therefore, it is recommended that the Local Government and East Nusa Tenggara BBKSDA take concrete measures to tackle the ambiguity of land ownership status, which is one of the root problems of conservation forest encroachment. These measures could begin with reviewing and updating data related to land boundaries and ownership status, followed by mediation between the government and the community to resolve border disputes fairly and transparently. Furthermore, it is essential for traditional institutions and local communities to actively participate in this process actively, utilizing local knowledge and traditions in determining fair and mutually recognized land boundaries. The Local Government and BBKSDA must also enhance efforts to socialize and educate the community about the importance of conservation forests, including the long-term benefits of forest conservation for environmental sustainability and the local economy. These efforts should be carried out through effective communication appropriate to the local cultural context so that the community can accept and value the importance of conservation forests.
Challenges of Hybrid Policing in Countering Online Fraud Networks: A Case Study from Sidrap Regency
Authors: Suarmita I. G. N. Adi , Purnomo Hadi
Published: March 2024

This research aims to examine the concept of hybrid policing in the context of crime prevention, specifically cyber fraud in Sidrap Regency. This research uses an empirical legal research method. All collected data is then qualitatively analyzed to describe the problem and answer the research objectives. The results show that the characteristics of cyber fraud in Sidrap Regency exhibit anonymity and disregard for geographical boundaries, with the primary motivation of the perpetrators being personal gain. They employ fake identities and compromised devices to execute their schemes, exacerbated by technological advancements, the public’s lack of awareness, and existing regulatory gaps. Therefore, it is recommended that the POLRI renew and adapt their policing model to be more responsive to the dynamics of cybercrime by implementing a hybrid policing approach. This involves active collaboration with community organizations in prevention efforts, which are expected to increase public awareness and strengthen the cyber security network. Additionally, developing an effective knowledge management system is advised, facilitating the exchange of information and strategies for handling cybercrime cases more efficiently. For researchers, it is crucial to examine further the social and psychological impacts of cybercrime on victims, which can contribute to forming a theoretical and practical foundation for a more holistic and victim-oriented approach to preventing and handling cybercrime in Sidrap Regency.
Desarrollo de una aplicación web que genere rostros de personas que no existen en el mundo real
Authors: Quezada-García María , Cajamarca-Castillo Kevin , Rivas-Asanza Wilmer , Mazón-Olivo Bertha
Published: March 2024

Con el creciente desarrollo de la Generative Adversarial Network (GAN), la generación de imágenes son un desafío emocionante en el campo del aprendizaje profundo y la inteligencia artificial. A nivel internacional se han desarrollado diversos trabajos relacionados a modelos de redes generativas antagónicas, pero una brecha significativa persiste en la falta de comparativas entre diferentes algoritmos. La capacidad de generar imágenes inexistentes que se asemejen en gran medida a las imágenes del mundo real es interesante para muchos casos de uso. En la presente investigación se propone desarrollar una aplicación web basada en redes neuronales preexistentes, utilizando la tecnología generativa antagónica para generar rostros de personas. En este estudio, se consideró como población de estudio a los 5.000 rostros que pertenecen el conjunto de datos FFHQ Face Dataset (2.500 rostro mujer) y (2.500 rostro de hombre). Las técnicas que fueron empleadas están basadas en dos modelos utilizando los siguientes algoritmos: Generative Adversarial Network (GAN) y Red Adversarial Generativa Convolucional Profunda (DCGAN). Las mediciones estadísticas de la matriz de confusión como resultado de la clasificación se utilizaron como métricas de rendimiento. Los resultados permiten concluir que el modelo (DCGAN) es el mejor método de clasificación, debido a su mejor predicción de los valores obtenidos de verdaderos positivos, y verdaderos negativos, además, la media de la precisión del modelo fue de 85,02%, superior al otro modelo. La aplicación desarrollada ha cumplido con éxito el objetivo principal de generar rostros humanos a partir de algoritmos de inteligencia artificial.
Inflammation in amebiasis and its modulation by the Autonomic Nervous System
Authors: Villalobos-Gómez Fabiola del Rocío , Ventura-Juárez Javier , García-Lorenzana Mario , Palacios-Marmolejo Anastacio
Published: March 2024

Neuroimmune regulation of inflammation is only beginning to be explored in depth. In the case of amebiasis, the inflammatory process prompted by E. histolytica has been well characterized, but the modulation of this process by neurotransmitters is not as well defined. Regarding the inflammatory process, it is known that neutrophils and macrophages are important cellular effectors in the host defense against E. histolytica. The production of proinflammatory cytokines (IL-1β, IL-8, INF-γ and TNF-α) and anti- inflammatory cytokines (IL-10 and TGF-β) is triggered by the activation of Toll-Like Receptors and two types of transcription factors: 1) nuclear factor kappa-light-chain- enhancer of activated B cells, and 2) activator of transcriptions: Toll-Like Receptors and these transcription factors are in turn modulated by the action of three neurotransmitters of the autonomous nervous system acetylcholine, adrenaline and noradrenaline that can activate cholinergic and adrenergic receptors of immune cells, and thus modify the inflammatory process induced by the parasite. A vagotomy of the liver of hamsters inoculated with E. histolytica induces a stronger response in tissues through a more abundant formation of collagen, together with an increase in the levels of IL-10 and INF- γ and a decrease in macrophages, which impedes the dissemination of trophozoites.
Antrenörlerin Zihinsel Yetersizliği Olan Bireylerde Sporun Etkilerine Yönelik Farkındalık Düzeyleri
Authors: İlhan Ekrem Levent , Arman Necip
Published: March 2024

Farklı meslek grupları zihinsel engelli bireylere hizmet etme potansiyellerini kullanarak bu bireylerin yaşam kalitesini artırabilirler. Antrenörler de bu meslek gruplarının içerisindedir ve göreve başlamalarıyla beraber zihinsel engelli bireylerle uzun süre çalışma imkanı bulmaktadırlar. Dolayısıyla bu çalışmanın amacı sporun zihinsel engelli bireyler üzerindeki etkileri konusunda antrenörlerin farkındalık düzeylerini ortaya koymaktır. Bu araştırmada betimsel bir nitelik taşıyan tarama modeli kullanılmıştır. Araştırmanın grubunu farklı branşlarda antrenörlük yapan 67’si kadın 138’i erkek toplam 205 gönüllü antrenörü kapsamıştır. Araştırmada veri toplama aracı olarak, “Kişisel Bilgi Formu” ve “Zihinsel Engelli Bireylerde Sporun Etkilerine Yönelik Farkındalık” ölçeği kullanılmıştır. Araştırmanın bağımlı değişkeni zihinsel engelli bireylerde sporun etkilerine yönelik farkındalık, bağımsız değişkenlerini ise; cinsiyet, yaş, özel gereksinimi olan sporcularla çalışma durumu, antrenörlük yaptığı branş, geçmişte branşında milli sporcu olma durumu, hizmet süresi, kendi spor geçmişinde ulusal ya da uluslararası alanda derece elde etme durumu, antrenörlük kademesi, yakınları arasında engelli birey olma durumunu kapsamaktadır. Veri toplama süreci sonunda elde edilen bulgular bilgisayar ortamına aktarılmış, verilerin çözüm ve yorumlanmasında grup karşılaştırmaları için t-testi, yaş ve hizmet yılı ile ölçek arasındaki ilişkiyi belirlemek için ise Pearson-Korelasyon analizi uygulanmıştır. Sonuçlara göre tüm değişkenler değerlendirildiğinde anlamlı bir farklılık bulunamamıştır. Ankete katılan antrenörlerin sporun zihinsel engelli bireyler üzerindeki etkisinin farkında oldukları tespit edilmiştir. Sporun, zihinsel engelli kişilerin fiziksel, zihinsel ve sosyal yaşamlarını iyileştirmede ve topluma entegrasyonlarını desteklemede rol oynadığı görülmüştür.
Implementasi Teori Perkembangan Kognitif Jean Piaget dalam Pembelajaran Matematika
Authors: Sudianto Sudianto , Ismayanti Syifa
Published: March 2024

Teori belajar adalah suatu langkah-langkah yang dapat membantu guru dalam mendidik dan menyampaikan pengetahuan kepada peserta didik. Teori belajar terdiri dari beberapa jenis, salah satunya teori perkembangan kognitif Jean Piaget. Tujuan dari penelitian ini untuk mengetahui bagaimana implementasi teori perkembangan kognitif Jean Piaget dalam pembelajaran matematika. Penelitian ini dilakukan dengan metode Systematic Literature Review (SLR). Artikel yang digunakan pada penelitian ini sebanyak 13 artikel jurnal yang diperoleh dari google scholar dalam kurun waktu 2017-2023. Hasil dari analisis data yang telah dilakukan bahwa teori perkembangan kognitif Jean Piaget cocok diterapkan dalam pembelajaran matematika. Dengan memperhatikan perkembangan kognitif peserta didik memudahkan guru dalam menentukan pembelajaran yang akan dilaksanakan sehingga kegiatan pembelajaran bisa lebih maksimal.
Information System Analysis of the Process of Opening a Savings Account at Bank "XYZ" Using the Cobit 4.1 Framework
Authors: Soleman Soleman , Mansuri Mansuri , IP Remi
Published: March 2024

Effective money storage and easy access system through the bank. The system used at Bank "XYZ" is still experiencing problems in the opening process. When customer service inputs prospective customer data, the input process exceeds the time specified by the system, the process will stop and return to the login display. Based on these problems, an information system audit is needed regarding the maturity level of Bank "XYZ"'s information system. The aim of this research is to determine the maturity level of the process of evaluating and maintaining ICT performance in information systems. This research uses the COBIT 4.1 framework which focuses on the Planning and Organization (PO), Deliver and Support (DS), and Monitor and Evaluate (ME) domains. The research results show that overall based on the maturity level in COBIT, the information system for the process of opening savings at Bank "XYZ" is at level 2 (repeatable but intuitive), which means the company has carried out a repetitive business process but there is no standard procedure for opening savings. To reach level 3 (define process) Bank "XYZ" needs to make process improvements by implementing the COBIT 4.1 Framework, namely PO, ME and DS which have a number of subdomains.
Sistem Pakar Diagnosa Kerusakan Motor Matic Menggunakan Metode Forward Chaining
Authors: Akhsa Amaliah Chintami Darti
Published: March 2024

CV. Alsa Indo Pratama Ahass merupakan sebuah perusahaan yang bergerak dalam perawatan dan perbaikan kendaraan bermotor. Setiap hari perusahaan ini menangani berbagai jenis kendaraan bertransmisi manual. Seiring perkembangan zaman, produsen kendaraan bermotor mulai menciptakan teknologi yang mempermudah para pengguna yaitu Motor Matic. Motor matic merupakan kendaraan yang menggunakan teknologi Continuosly Variable Transmition (CVT). Teknologi yang tergolong baru ini berbeda cara penangannya dari kendaraan bermotor yang menggunakan transmisi manual. Kurangnya tenaga ahli yang menguasai teknologi serta beberapa teknisi merupakan teknisi muda membuat penanganan terhadap motor matic di CV. Alsa Indo Pratama kurang maksimal. Melihat hal ini maka penulis membangun suatu sistem pakar untuk mendiagnosa kerusakan CVT pada motor matic. Sistem pakar ini dibangun dengan mentransfer keahlian dan pengetahuan pakar kendaraan matic ke dalam bahasa pemrograman yang diharapkan dapat membantu para teknisi menangani kendaraan matic ini. Sistem ini diuji menggunakan White-box testing agar menjamin bahwa sistem ini bebas dari kesalahan logika dan terjamin validitasnya. Diharapkan dengan dibangunnya sistem ini, CV. Alsa Indo Pratama Ahass dapat menangani permasalahan kerusakan CVT kendaraan motor matic sehingga pelayanan yang dihasilkan lebih baik.
Analisis Sentimen Terhadap Aplikasi Pluang Menggunakan Algoritma Naive Bayes dan Support Vector Machine (SVM)
Authors: Maulana Bagas Akbar , Fahmi Muhammad Jazilul , Imran Ari Muhamad , Hidayati Nutriana
Published: March 2024

Analisis sentimen merupakan proses menganalisis teks untuk menentukan sentimen yang diungkapkan, seperti positif, negatif, atau netral. Analisis sentimen dapat digunakan untuk berbagai tujuan, seperti memahami opini publik, mengukur kepuasan pelanggan, dan mendeteksi penipuan. Dalam penelitian ini, kami menerapkan metode klasifikasi sentimen untuk menganalisis ulasan aplikasi Pluang. Aplikasi Pluang adalah aplikasi investasi digital yang menawarkan berbagai produk investasi, seperti emas, saham, dan reksa dana. Kami menggunakan dua model klasifikasi sentimen, yaitu Naive Bayes dan SVM. Hasil penelitian menunjukkan bahwa model SVM bekerja lebih baik dibandingkan model Naive Bayes. Secara spesifik, model SVM memiliki akurasi sebesar 99,50%, presisi 99,67%, recall 99,33%, dan skor F1 sebesar 99,50%. Sedangkan model Naive Bayes memiliki akurasi sebesar 99,25%, presisi sebesar 99,44%, recall sebesar 99,06%, dan skor F1 sebesar 99,25%. Kelebihan model SVM dibandingkan model Naive Bayes adalah kemampuannya untuk membedakan teks positif dan negatif dengan lebih baik. Ini disebabkan oleh beberapa faktor, antara lain: Data negatif memiliki karakteristik yang lebih beragam daripada data positif, SVM menggunakan teknik kernel yang mampu memetakan data ke dalam ruang dimensi yang lebih tinggi, sehingga dapat memodelkan hubungan antar data dengan lebih baik. Secara keseluruhan, penelitian ini menunjukkan bahwa SVM merupakan metode klasifikasi yang efektif untuk menganalisis sentimen ulasan aplikasi Pluang.
Aplikasi Startup Otocity Berbasis Design Thinking untuk Memudahkan Pengguna Kendaraan dalam Mengatasi Kerusakan dan Penitipan Kendaraan
Authors: Nisa Salma Aula
Published: March 2024

Program UI/ UX Design Bersertifikat diselenggarakan oleh Yayasan Bakti Achmad Zaky dan dikukung oleh Kemdikbud Ristekdikti. Program dirancang untuk mempersiapkan UI/ UX Designer yang berkualitas dan dapat bersaing diera digital. Tema yang diangkat adalah tentang kendaraan. Dimana masalahnya sulit menemukan bengkel terdekat dari lokasi atau mencari tempat penitipan kendaraan. Jadi solusinya adalah dengan membuat aplikasi OTOCITY yaitu aplikasi bengkel dan penitipan kendaraan dengan menggunakan metode Design Thinking, karena dengan menggunakan aplikasi tersebut pengguna kendaraan tidak perlu antri atau datang untuk mendapatkan nomor antrian. Tujuan Aplikasi OTOCITY tidak hanya memudahkan para pengguna kendaraan namun juga memudahkan para pemilik bengkel dan penitipan kendaraan. Metode Design Thinking adalah proses berulang untuk memahami pengguna, menantang asumsi, dan mendefinisikan kembali masalah dalam upaya mengidentifikasi strategi. Salah satu keuntungan menggunakan metode design thinking adalah kemampuannya untuk mengurangi risiko. Jadi hasil aplikasi OTOCITY pun sudah teruji oleh para mentor dan sudah diuji kepada user atau pengguna kendaraan yang menggunakan smartphone
Evaluasi Layanan Publik pada Platform E-Government menggunakan Indeks Layanan Publik Elektronik dan Metode Importance Performance Analysis
Authors: Permatasari Indah , Terttiaavini Terttiaavini , Heryati Agustina , Saputra Tedy Setiawan
Published: March 2024

Dinas Kependudukan dan Pencatatan Sipil Kota Palembang telah menerapkan pendekatan inovatif untuk meningkatkan efisiensi dan aksesibilitas melalui pengenalan Platform E-Government. Untuk mendapatkan tanggapan masyarakat, sangat penting untuk mengukur kepuasan pengguna terhadap Layanan Website sebagai langkah awal dalam proses perbaikan. Penelitian ini bertujuan untuk menilai Layanan Website Disdukcapil dengan mengidentifikasi tingkat kepuasan pengguna, mengevaluasi kinerja platform, dan memberikan rekomendasi perbaikan guna meningkatkan efektivitas layanan. Indikator diambil dari Indeks Layanan Publik Elektronik, dengan pengujian validasi menggunakan SPSS, dan Metode Importance Performance Analysis (IPA) digunakan untuk menganalisis sejauh mana kinerja aktual suatu variabel sesuai dengan harapan pengguna. Penelitian ini menghasilkan indeks layanan elektronik sebesar 3,417, menunjukkan penilaian yang sangat baik terhadap layanan E-Government. Namun, uji sampel berpasangan mengungkapkan adanya perbedaan yang signifikan antara kinerja aktual dan harapan pengguna. Analisis ini menegaskan perlunya perbaikan layayan guna meningkatkan kepuasan pengguna. Rekomendasi perbaikan yang dihasilkan dari analisis ini diharapkan dapat memberikan kontribusi positif terhadap efektivitas layanan publik elektronik di Dinas Kependudukan dan Pencatatan Sipil Kota Palembang.
Analysis of the Interconnection between Digital Skills of Human Resources in SMEs and the Success of Digital Business Strategy Implementation
Authors: Sutrisno Sutrisno , Kraugusteeliana Kraugusteeliana , Syamsuri Syamsuri
Published: March 2024

The advancement of information technology has transformed the way SMEs operate, from marketing aspects to inventory management. Digital business opens up new opportunities for SMEs but also demands new skills from human resources to keep up with these developments. The objective of this research is to analyze the interconnection between the digital skills of human resources in SMEs and the success of implementing digital business strategies. This research method focuses on qualitative literature review using Google Scholar as the data source, especially for articles published between 2021 and 2024. The study results indicate that the role of human resources in an increasingly digital business world is crucial. The digital skills possessed by human resources not only affect the effectiveness of implementing digital business strategies but also impact the competitiveness and sustainability of SMEs in the constantly changing market. A deep understanding of the market, creativity in innovation, and adaptability are important factors in ensuring business success in this digital era.