bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Motivation, Incentives on ASN Professionalism is Mediated by Job Satisfaction in the Badung Regency Governmen
Authors: Liando Frisky F. , Gorda A. A. N. Oka Suryadinatha
Published: May 2024

The purpose of this research is to find out and analyze the influence of motivation and incentives on the job satisfaction of Badung Regency Government ASN, then to find out and analyze the influence of motivation, incentives and job satisfaction on the professionalism of Badung Regency Government ASN, then to find out and analyze the influence of the role of job satisfaction in mediating the influence of motivation and incentives on the professionalism of Badung Regency Government ASN. The population of this research is the State Civil Apparatus (ASN) in the Badung Regency Government, totaling 6,890 employees.
The number of respondents in the sample was between 90 and 180 respondents. Data collection in this research used a questionnaire. The data analysis technique consists of descriptive analysis and inferential analysis using the Partial Least Square (PLS) approach. The results show that: Motivation has a positive and significant effect on job satisfaction. Incentives have a positive and significant effect on job satisfaction. Motivation has a positive and significant effect on professionalism. Incentives do not have a significant effect on professionalism. Job satisfaction has a positive and significant effect on professionalism. The influence of motivation on professionalism through job satisfaction is positive and significant. The effect of incentives on professionalism through job satisfaction is positive and significant.
The European Parliament as the voice of the European citizens? Examining the European Parliament’s role as a representative of the European citizens in the 2019 elections
Authors: Baccarini Roberto
Published: May 2024

The European Parliament is considered a solution to the democratic deficit because the citizens of the EU directly elect it. This article aims to examine the validity of this claim. Concerning representativeness, the focus is on the homogeneity of rules and procedures used for electing the members of the European Parliament (MEPs). This homogeneity is considered as necessary for the EP to represent the EU citizens. Thus, it aims to assess the impact of the United Kingdom's withdrawal from the European Union on the level of homogeneity of the rules used to conduct the 2019 European Parliament elections. This work claims that the European Parliament's role as representative of European Citizens is weakened by the consistent level of heterogeneity characterising the electoral rules used to elect it and that the withdrawal of the UK and the partial redistribution of seats simultaneously increased and decreased the level of homogeneity of the rules used to elect the MEPs.
Absenteeism from Lectures Among Medical Students in Casablanca
Authors: Mouzoun Fatima Zahra , Berrami Hind , Boubekri Zineb , Niyonsaba Adelin , Barkouk Amal , Belayachi Nouha , Jallal Manar , Serhier Zineb , Othmani Mohammed Bennani
Published: May 2024

Introduction: Absenteeism among medical students is a remarkable issue, affecting learning process and academic performance. The present study aimed to estimate the prevalence and associated factors to medical students’ absenteeism. Methods: A cross-sectional study was carried out at the Faculty of Medicine and Pharmacy in Casablanca using self administered questionnaires distributed to medical students from year one to year five levels randomly selected. The associations between absenteeism and all variables was identified by univariate and multivariate logistic regression analyses. Results: 373 students completed the questionnaire. The prevalence of absenteeism in this study was 19.6% (95% CI=[15.9-23.9]). Multivariate analysis revealed several factors significantly associated with absenteeism from lectures, including age (AOR = 1.63, 95% CI: 1.07–2.48), being passionate about medicine (AOR = 0.22, 95% CI: 0.06–0.75), mode of transportation (AOR = 2.47, 95% CI: 1.06–5.77), lack of interaction between lecturer and students (AOR = 11.97, 95% CI: 1.39-102.46), dislike the teaching style (AOR = 6.87, 95% CI: 2.55-18.48), the ease of the subject (AOR = 2.96, 95% CI: 1.05-8.33) and students who prefer to study alone (AOR = 2.88, 95% CI: 1.26-6.56). Conclusion: At the Faculty of Medicine and Pharmacy in Casablanca teaching strategies and lecture environment were the main factors related to absenteeism from lectures. Exploring a variety of teaching methods such as hybrid learning can be a beneficial preventive intervention.
Cerebral Venous Thrombosis Indicative of Polycythemia Vera: Case Report
Authors: Boubga Taoufik , Mohammed Ennmer , Taous Abdellah , Berri Maha Ait , Boulahri Tarik
Published: May 2024

Polycythemia vera, a myeloproliferative disorder, seldom leads to cerebral venous thrombosis, making this association a rare occurrence. Here, we present the case of a 62-year-old patient without significant medical history, who was admitted due to a one-month history of intracranial hypertension syndrome. Upon admission, papillary edema (stage II) was observed, along with a lack of focal neurological signs. MRI angiography revealed thrombosis in the right lateral sinus. Further diagnostic investigation confirmed the presence of polycythemia vera. The patient was initiated on anti-edematous and anticoagulant therapy, followed by bloodlettings and cyto-reduction treatment, resulting in a favorable clinical outcome.
The Flipped Classroom Model in Teaching the Primary School Mathematics Teaching Methods Course for Primary Education Students at Tan Trao University
Authors: Thuy M. A. Nguyen Thi Thu
Published: May 2024

Teaching according to the “flipped classroom” model is one of the blended learning methods. In this article, we discuss some research results from authors both domestically and internationally on the flipped classroom model, thereby proposing a process and implementation of organizing teaching according to this model in teaching the primary school mathematics teaching methods course for Primary Education students at Tan Trao University. Applying the “flipped classroom” model in online teaching contributes to: 1/ fostering active engagement and interest in learning for students; 2/ innovating teaching methods, enhancing learning effectiveness, and fostering the development of critical thinking and other skills for students.
Prosthetic Management of Malpositioned Implant in RPD Case Report
Authors: Nihel Charfi , Wafa Mami , Wadii Bembli , Rim Bibi , Nadia Frih
Published: May 2024

Removable dentures in classe I KENNEDY APPLEGATE remain an essential prosthetic challenge as support is required from the teeth, the mucosa, and the underlying residual ridges. Dental implants can improve denture retention, stability, and support in distal extension removable partial denture. However, a malpositioned implant can complicate tooth/implant-supported condition. This case report describe a 66-year-old female patient treated with maxillary implant -supported removable partial denture (RPD). Both the implants were placed in first premolar site. However, the implant on the left side presented severe facial inclination. We suggest that the discharge of the prosthetic edge with using a laboratory non retentive nylon Patrice’s on the Intaglio of metal housing locator attachment can solve the problem of denture insertion.
Advances in The Assessment of the Sedative Effect of Remimazolam
Authors: Zhao Tang-yuan-meng
Published: May 2024

Purpose of Review: Remimazolam is a new short-acting benzodiazepine in the final stages of clinical development. The methods of monitoring sedation and assessing the depth of anesthesia for benzodiazepine sedative drugs have been fraught with controversy in clinical work. As a newly released short-acting anesthetic sedative drug that can be continuously pumped, appropriate anesthetic monitoring and sedation depth assessment tools can better help anesthesiologists make clinical decisions and reduce the emergence of perioperative complications in patients.
Recent Findings: Clinical trials of remimazolam have been completed at home and abroad in various phases, and much progress has been made, but the effective sedation monitoring means of remimazolam are still not conclusive.
Summary: Remimazolam has a rapid onset of action and a high rate of metabolism in the body; tissue accumulation and delayed awakening are rare. At the same time, it can be safely applied to elderly patients with a low cardiopulmonary function inhibition rate, accurate anesthesia effect, and satisfactory quality of awakening. By comparing various methods of sedation depth monitoring, the data correlation is high, which can be of significant importance for remimazolam sedation depth monitoring.
A TRACER STUDY ON THE BACHELOR OF SCIENCE IN BUSINESS ADMINISTRATION MAJOR IN MARKETING MANAGEMENT GRADUATES FROM BATCH 2022-2023
Authors: Aliemar Villasin  , Ma.Elena G.Litob
Published: May 2024

This tracer study assessed the employment status and job readiness of graduates from the Bachelor of Science in Business Administration-Marketing Management program at a local college in Kapalong, Davao del Norte, focusing on batches from 2022 to 2023. Using a descriptive research methodology, the study gathered data from 143 alumni through an online survey conducted via Google Forms. Findings revealed that 88.11% of the surveyed graduates were employed, with 46.85% working in marketing-related jobs, 6.29% in academia, and 34.97% in government or non-job-related professions. Employment status varied, with 38.46% as a permanent position, 27.27% on contractual terms, 10.49% as job orders, another 10.49% self-employed, and 1.40% in probationary positions. In the same manner, 35.66% of these graduate-respondents are now earning a salary range of Php.11,000-15,000 and 53.15% of them were able to find a job within 1-3 months after graduation. Additionally, 2.10% of the respondents were pursuing further studies, specifically masters degrees. The graduates rated very high in terms of work attitude, the quality of education provided, and the development of skills and abilities, consistently exhibiting these positive attributes. However, the study identified a notable deficiency in computer and ICT skills among the graduates. Thus, it is recommended that the college enhance its marketing curriculum by incorporating practical training in commonly used computer and ICT software to better prepare students for the demands of the job market.
KEYWORDS: Tracer Study, Marketing Management Graduates, Employment
UNDERSTANDING POSITIVE PSYCHOLOGY THROUGH THE LENS OF INDIAN KNOWLEDGE SYSTEM: INSIGHTS FROM SHRIMAD BHAGAVAD GITA
Authors: Animesh Das  , Prof. Rakesh Rai
Published: May 2024

In todays educational landscape, where academic success shapes the future of the learners, the intense competition for excellence often pushes them into the dark realm of anxiety and depression. This struggle results in isolation, identity crisis and gives birth to various health issues such as hypertension, obesity, cardiovascular disorders and heightened aggression. Positive Psychology is a branch of psychology that emphasises on the importance of cultivating positive emotions such as joy, gratitude and contentment. It focuses on leveraging personal strengths and mental resilience to help individuals cope with lifes challenges more effectively. Bhagavad Gita holds an important place in Indian knowledge system as its timeless wisdom has guided the people over centuries. What positive psychology says today was said long back by Sri Krishna on the battlefield of Kurukshetra to bring Arjuna out of sadness and confusion and prepare him for the war. Through this paper, an humble attempt has been made to explore the ideas of positive psychology from the perspective of Bhagavad Gita.
KEYWORDS: Shrimad Bhagavad Gita, Positive Psychology, Indian knowledge system, Stress Management, School Education.
MANUAL THERAPY TECHNIQUES FOR THE ACROMIOCLAVICULAR JOINT DYSFUNCTION – A NARRATIVE REVIEW
Authors: Nallapareddygari Bhavya Sree  , Dr Senthil Kumar  , Dr Shwetha Sashidharan
Published: May 2024

INTRO/BACK GROUND
Ac joint dysfunction is a prevalent cause of shoulder discomfort. As far as we are aware, there are currently no published studies focused on the manual therapy management of AC joint dysfunction. However, manual physical therapy has proven successful in treating various other shoulder conditions. To address this, recent research has started to investigate whether manual techniques are more effective in treating ac joint dysfunction.
OBJECTIVE
Aim of this study on the literature review pointing on the available evidence for the manual therapy interventions in acromioclavicular joint dysfunction patients.
METHODS
Research involved a computerized data base used for searching articles were Science direct, Pedro, PubMed, goggle scholar search pertaining to studies that include the manual therapy among acromioclavicular joint dysfunction Patients
RESULTS:
These 10 studies were based on the inclusion exclusion criteria were included in this review the methods used in all these studies were strengthening exercises , transverse friction massage, joint mobilization, myofascial release techniques, active passive motion exercises, scapulothoracic exercises, peri joint muscle exercises, joint stability exercises with different sets of exercises for muscle activation and range of motion and function these manual therapy techniques aims to alleviate inflammation recover the shoulder pain free rom and restore the proper function of soft tissue and joint.
CONCLUSION:
We conclude from this review that a variety of manual treatment procedures have been shown to be useful and effective in treating patients with AC joint dysfunction. There is, however, a dearth of data on the use of manual therapy procedures or interventions to treat ac joint dysfunction. More investigation is required to determine the precise role that manual therapy strategies may play in managing ac joint dysfunction.
Digital content and reading encouragement initiatives... A vision towards a knowledge society
Authors: Bezan Dr. Hanan Al Sadeq
Published: May 2024

Perhaps it is enough to read the importance and destiny and consider it a key to knowledge and the achievement of civilized renaissance, as it is the first divine command that came with the faithful revelation of the illiterate prophet, the last of the prophets and messengers. This is indisputable proof that reading outweighs everything of importance and value in life.
Therefore, no two disagree that the decisive factor in the present and future life revolves around knowledge, by which the progress and superiority of nations and societies is measured and their arrangement among the developed and less developed countries of the world, since the early nineties of the last century, and with the increasing spread and development of the use of information and communication technology The governments of all countries are actively seeking to pay attention to information management, knowledge production, and civilizational value creation.
Of course, the use or consumption of information and the production of knowledge, and the growing interest in the growing awareness of the role of creativity and innovation by using knowledge to add value, come only through the availability of digital content in a way that guarantees availability and rapid access in order to enhance knowledge and cultural openness and create information awareness among generations.
At this juncture, the problematic of this research paper emerges in: The nation of Iqra does not read, as it is one of the least countries in the world in demand for reading, which negatively affects its awareness and awareness of achieving the civilizational renaissance, as the main question on which the axes of the paper are based to answer is:
• What is the method or the elements through which it is possible for the Arab countries to be a nation of reading in the full sense of the word, and to be able to achieve the civilizational renaissance and progress towards the knowledge society with merit and competence?
'Uma das coisas que mais agrega valor é o orgânico’ – Novas trajetórias e singularidades no mercado dos produtos orgânicos
Authors: Lucion Jéssica Maria Rosa , Radomsky Guilherme Francisco Waterloo
Published: May 2024

As they were regulated and institutionalized, organic products took on new trajectories and meanings with the emergence of a more varied market focusing on specific audiences and new qualification references. In this paper we investigate some of the new meanings and different qualifications organic products have assumed by analyzing their new trajectories and singularities within an increasingly flexible and dynamic market containing wider and more heterogeneous range of actors and distinct products that circulate around the organic concept but are neither rigidly defined by or dependent upon this meaning. Using data from primary and secondary sources on how these products were singularized, we attempt to demonstrate that throughout the process of regulating and institutionalizing organic products, “organic” has not only become commodified but also assumed other overlapping meanings, with this characteristic potentially becoming less central or products even ceasing altogether to be organic. In our analysis we highlight trade fairs that focus on these products, their entry into large food companies and retailers, ultra-processed organic products, and how they approximate other qualification references (such as the concepts of vegan, diet, and light).
Microstructure evolution and ductility improvement of additively manufactured biodegradable zinc–magnesium alloys via annealing
Authors: Han Changjun , Huang Jinmiao , Ye Xiangling , Liu Boxun , Dong Zhi , Yang Yongqiang , Gao Junqing , Yang Kuangyang , Chen Guocai
Published: May 2024

Zinc–magnesium (Zn–Mg) alloys, fabricated by laser powder bed fusion (LPBF) additive manufacturing techniques, have emerged as promising candidates for biomedical implants due to their biodegradation capability, superior mechanical strength, and excellent biocompatibility. However, LPBF-fabricated Zn–Mg alloys still face challenges related to extremely low ductility and limited exploration of degradation characteristics. In this study, the impact of Mg incorporation on the printability, degradation properties, microstructure, and mechanical properties of LPBF-fabricated Zn–Mg alloys was primarily investigated. Furthermore, we proposed a viable annealing post-processing route for the first time to tailor the microstructural characteristics of the fabricated Zn–Mg alloy and enhanced its limited ductility. The results demonstrated that by applying a laser power of 80 W and a scanning speed of 600 mm/s, the relative density of LPBF-fabricated Zn–Mg alloy reached 98.62%. Increasing the Mg amount from 1 to 5 wt% refined the grain size while promoting an increase in Mg2Zn11 and MgZn2 phases. Among these compositions, the Zn–1Mg alloy exhibited the greatest degradation rate at 0.126 mm/year. The annealing treatment facilitated the microstructure evolution of the Zn–1Mg alloy, resulting in equiaxed grains, increased average grain size, high-angle grain boundaries, and enrichment of Mg at grain boundaries. After annealing at 300°C for 0.5 h, the tensile strength of Zn– 1Mg alloy decreased from 254.92 to 170.93 MPa, while the elongation significantly increased by a factor of 14.3 from 0.55% to 8.43%. These findings provide valuable insights into an effective post-processing approach for tailoring the microstructure and resultant mechanical properties of LPBF-fabricated Zn and its alloys.
In vitro investigation into the dynamics between Acinetobacter baumannii, bacteriophage, and mammalian bronchial epithelial cells
Authors: Yan Wei , Zhang Pengfei , K.W. To Kenneth , S.Y. Leung Sharon
Published: May 2024

Antibiotic resistance is escalating due to the rapid emergence of multidrug-resistant bacteria and the stagnation in new antibiotic development. Bacteriophage, a natural enemy of bacteria, has re-emerged as a promising alternative in the post-antibiotic era. However, none of the recently completed randomized, placebo-controlled, and double-blinded clinical trials on phage therapy could confirm its efficacy. One of the major impediments is the lack of understanding of the phage, bacteria, and host body interactions. Our work investigates the dynamics between Acinetobacter baumannii, bacteriophage, and a mammalian bronchial epithelial cell line (BEAS-2B) in a coculture system. Our results demonstrated that the bactericidal effect of bacteriophage could be augmented in the presence of non-mucus-producing epithelial cells (by 3 – 5 log). Adsorption study indicated that both phages and bacteria could adhere to the epithelial cells, subsequently promoting their contact and the phage lytic effect. The presence of epithelial cells could also effectively inhibit/delay the emergence of phage resistance. These findings suggested that evaluating the in vitro antibacterial efficiency of bacteriophage in the presence of mammalian cells may yield better predictions of the therapeutic outcomes of bacteriophage therapy.
Colorado National Monument: Paleontological resource inventory (public version)
Authors: Shaffer Austin , Tweet Justin , Santucci Vincent
Published: May 2024

Colorado National Monument (COLM) in western Colorado was established on May 24, 1911 with the purpose of preserving, understanding, and enjoying the natural and cultural resources of the landscape, focusing on the history, erosional processes, and geology present. Although not explicitly mentioned in the monument?s purpose statement, the paleontological resources of COLM are nevertheless important. Significant fossils have been known from the area since the late 19th and early 20th centuries, and from COLM specifically within a few decades of the monument?s founding. The direct urban interface of COLM with Colorado?s Grand Valley provides unique management concerns for fossils and other resources of the monument.

While COLM preserves a long geologic history (roughly 1.7 billion years ago to the present), the fossils preserved at the monument mostly come from sedimentary rocks of the Mesozoic Era. The paleontological resources of COLM include both body fossils and trace fossils of a wide variety of organisms (e.g., freshwater mussels, dinosaurs, plants) representing diverse paleoenvironments.

In order to assess the paleontological resources of COLM, a field inventory was conducted from April to November 2023, visiting all previously reported fossil sites and documenting new localities. A total of 226 paleontological localities were verified during this fieldwork, of which nearly two-thirds (146 sites) were newly documented. Two more were discovered in March 2024. These 228 localities are distributed throughout much of the monument and many of the geologic units, with higher concentrations present in certain units (e.g., the Morrison Formation). Fieldwork was supplemented by the review of published and gray literature and assessment of COLM paleontological collections.

A number of significant paleontological discoveries were made during this inventory, including the first documented fossils (dinosaur tracks, plant fossils, and dinosaur skin) from the Naturita Formation within COLM and multiple novel fossil occurrences (e.g., likely the oldest-known fish otoliths in North America and possibly one of the only Jurassic ankylosaur tracks known globally). When considered alongside previously identified significant fossil finds from COLM (e.g., one of only three known turtle tracksites in the Morrison Formation and potentially one of the only known lizard trackways in the same unit), the paleontological resources of the monument are of high scientific importance. Future research on the paleontological resources of COLM has a high potential for identifying important fossil specimens and/or describing new species.

This report provides foundational data on the scope, significance, and distribution of paleontological resources at COLM and provides recommendations to support the management, interpretation, and research of these resources.
Pretreatment of lignocellulosic biomass for bioethanol production
Authors: Raj Sonali
Published: May 2024

This review surveys recent progress in pretreatment methods for enhancing bioethanol production from lignocellulosic biomass. Various pretreatment techniques, including physical, chemical, and biological approaches, are evaluated for their efficacy in breaking down biomass structure and improving enzymatic digestibility. Key parameters influencing pretreatment effectiveness and integration with downstream processes are discussed. The review highlights promising strategies and identifies areas for further research to optimize bioethanol production from lignocellulosic feedstocks.
Analysis and Prediction of COVID-19 Using Growth Analysis Models: A Case Study
Authors: Lone Kalimullah , Sofi Shabir Ahmad
Published: May 2024

The coronavirus disease 2019 outbreak has added to the development of novel methods to study the epidemiological and predictive nature of the pandemic. Mining such data is necessary as this data is full of trends and information. Using data mining techniques allows us to extract and process such data to predict the pandemic's trends and behavior. Analysis, evaluation, and prediction are performed on Jammu and Kashmir's data during the period 09th of March 2020 to 10th of February 2021. The work is done on the dataset of patients provided by the Department of Information and Public Relations, Government of Jammu and Kashmir. Various mathematical models and techniques were used to predict the Virus spread and occurrence with the help of symptoms. We aim to propose a model to predict the virus occurrence based on the symptoms and epidemiological nature of the pandemic. The purpose of this study is to understand the virus occurrence and distribution. The work has helped our government to find the most infected areas and future challenges to tackle any such pandemic. The trends and behavior of the virus in Jammu and Kashmir were studied. People under observation, people tested for the virus, positive, negative, recovered, active, and deaths were keenly observed. The prediction to find an infected patient was carried out with the help of symptoms. The results obtained from the prediction model are verified with the actual results.
The Effect of Coffee Consumption on the Level of Adrenalin Blood Serum in the Periodontitis Model: An In Vivo Study
Authors: Susilawati I Dewa Ayu , Mochammad Fahmi
Published: May 2024

Background: Adrenalin was supposed to have an anti-inflammatory effect; hence adrenalin concentration in blood serum might be lower in inflammatory diseases. Coffee contains caffeine that is thought to have the potency to increase adrenalin secretion in inflammatory diseases. This study aimed to analyze the effect of coffee consumption on adrenalin blood levels in periodontitis rat model.
Methods: This in vivo experimental study used the post-test-only control group design. Wistar male rats (Rattus novergicus) were divided into four groups (four rats/group) i.e. 1) Periodontitis (no coffee), 2) periodontitis + coffee, 3) Coffee (no periodontitis), 4) Control (no coffee, no periodontitis). The periodontitis rat model was made by injecting periodontitis bacteria Phorpyromonas gingivalis in the buccal mucosa of the lower molar tooth three times a week for 4 weeks. A single dose (0.6 mL d–1) of ground coffee infusion (equal to one cup per day for humans) was given to each rat in the coffee group, for 28 d. At the end of the study, all of the rats were sacrificed and blood was drawn intra-cardially. Blood serum adrenalin concentration was analyzed using Enzyme-linked immunosorbent assay (Elisa).
Results: The Periodontitis group showed significantly lower serum adrenalin (p< 0.05) than others. Coffee consumption in periodontitis rats affected a significantly higher adrenalin blood serum level (p < 0.05).
Conclusion: Coffee consumption could replenish the level of blood serum adrenalin which decreases in periodontitis. Further studies are needed to elucidate the modulation mechanism of coffee-adrenalin-inflammation.
Vulnerability of the Pteridoflora Towards Climate Change in the West Albertine Rift: Case of the Mountain’s Stages of the Kahuzi-Biega National Park in the Democratic Republic of the Congo
Authors: Mokoso Jean De Dieu Mangambu , Marie Fundiko Cakupewa , Habimana Honorine Nahobavuka , Sefu Josué Aruna , Zabo Idrissa Assumani , Botelanyele Francine Kirongozi , Sefu Josué Aruna , Roger Katusi Lomalisa
Published: May 2024

The present article aims at analysing the floristic composition of Lycophytes and Ferns to test the disturbances on the vegetation structure occurring in the mountains zones of the Kahuzi-Biega National Park (KBNP), further, to prove/underline the main threat and the vulnerability which actually is impacting the biodiversity in the mountains of the Western Albertine Rift due to climate changes and resulting in habitat loss as well as result of anthropogenic activities. The KBNP is located at the crossroad of the phytogeography regions of the Guinea-Congolese and Afromontane between 650 to 3326 m of altitude. During 10 years, we conducted comparison studies in the habitats (disturbed and undisturbed) encountered on the vegetation that scales between 1250 à 3300 m of altitude in 30 plots, 15 transects on a one kilometre. The results obtained reveal a variation in the flora composition within the three stages. The difference in the height, the diametric distribution (trees and shrubs) as well as the presence of Pteridophytes between undisturbed and disturbed habitats is highly significant within the 10 years’ observations. In stable and mature parcels, Pteridophytes constitute a very rich, diversified and stable population. Permanent threat manifested through the fragility of the habitats and is further translated by a modification of the floristic composition of the canopy, and sometimes trough the taming of the undergrowth in disturbed parcels. The mountainous part of the KBNP might probably constitute a climatic refuge for Pteridophytes in the Albertine Rift considering their diversity. Furthermore, considering these adaptations, the diversity and the specificity of the biotopes occupied, as well as the bioecological services recognized to Lycophytes and Ferns, they are the real markers for bioindicators of the delicatessen towards climate changes observed in the western rift Albertine. However, anthropogenic effects and sometimes, natural hazards resulting in this protected area, may also constitute a source of vulnerability for Pteridophytes
Impact of Micronutrient Profiles on the Pathological Features and Clinical Outcomes of Colorectal Tumors with Microsatellite Instability
Authors: Yong Yang , Cunfa Wang , Chan Deng , Xia Liu , Xiaoxu Li
Published: May 2024

We assessed the role of nutritional factors in conjunction with pathological and clinical characteristics of colorectal tumors with microsatellite instability. Data from 1,135 patients diagnosed with colorectal cancer were analyzed, employing immunohistochemistry for mismatch repair protein detection and polymerase chain reaction-capillary electrophoresis for microsatellite instability gene detection. To explore potential correlations with microsatellite instability status, we evaluated patients’ dietary habits and micronutrient levels, particularly folate and selenium. We discovered that 10.84% of the patients had mismatch repair protein deletions, with MLH1 and PMS2 double deletions being the most prevalent. Notable differences were identified in serum carcinoembryonic antigen levels, tumor location, tumor-node-metastasis stage, tumor differentiation, mucous composition, gross type, size, nodules, nerve invasion, and lymph node ratio between deficient mismatch repair and proficient mismatch repair patients. The deficient mismatch repair group had lower carcinoembryonic antigen levels, a higher incidence of right-sided colon cancer, earlier tumor-node-metastasis stage, poorer differentiation, more mucinous components, larger tumors, and fewer nodules and nerve invasions. High concordance (98.59%) was observed between immunohistochemistry and polymerase chain reaction-capillary electrophoresis techniques in microsatellite instability detection, underscoring the reliability of these methods. Integrating the nutritional parameters with conventional clinical assessments offers a nuanced understanding of the heterogeneity of colorectal cancer, with significant implications for diagnosis and treatment strategies.
Chrysophanol Attenuates Liver Fibrosis via Downregulation of Disintegrin and Metalloprotease 17 in the Thioacetamide Mouse Model
Authors: Ya-Hsuan Lin , Chan-Yen Kuo , Chan-Yen Kuo , Chan-Yen Kuo
Published: May 2024

It is unclear whether chrysophanol affects liver fibrosis via the regulation of ADAM17, a multifaceted enzyme involved in immune regulation, central nervous system function, and cancer development. This article underscores that the chrysophanol treatment reduced collagen deposition in thioacetamide-induced liver fibrosis mice while downregulating ADAM17.
The Impact of E-Marketing on Consumer Satisfaction during Pandemic Time
Authors: Zeqiri Albulena Avdili , Desku Behrije Ramaj , Ilieska Karolina
Published: May 2024

During the pandemic, E-marketing was of great importance to enterprises in general. Digitized enterprises or enterprises that have been digitized during the pandemic have managed to develop their work processes without stalling in their development. At the time when everything stopped working, the companies that had already digitized processes within their companies were managing to cope with the situation that had gripped the whole world. The approach of enterprises in the time of the pandemic has greatly influenced the perception and importance of the digitalization of enterprises in the daily work processes. Communication, process management, and employee management have been a key factor in not stalling processes, ie in maintaining the health of employees of those enterprises. As a result of the COVID-19 crisis, the majority of business executives have ordered their organizations to digitize at least a portion of their operations to safeguard workers and cater to clients who are experiencing limited mobility. We have all watched what is undoubtedly going to go down in history as the widespread adoption of digital access to services and remote work, even though many doubters have not recognized this as a viable prospect. Online ordering and delivery have become the primary business of grocery businesses. In many nations, the emphasis in schools is entirely on online education. Plans for "online" supply chains and factories are being actively developed by manufacturers. Although in some regions the masses have started to reopen and businesses are opening, many businesses are still considering digitalization and further development of their internal processes as a priority. Customer satisfaction is one of the greatest assets of any business, including e-business in today's competitive environment. Several factors can help e-businesses to build a base for their customers. It undoubtedly includes service and customer satisfaction which can be the determinants of success.
Dispensa coletiva. Negociar ou não negociar?
Authors: Ribeiro dos Santos Enoque
Published: May 2024

Artigo que tem por finalidade apresentar a realidade da dispensa em massa no Brasil em cotejo com a doutrina relativa à temática nos países de capitalismo avançado, notadamente na União Europeia, bem como a jurisprudência dominante no Brasil e o tratamento da matéria no âmbito da OIT – Organização Internacional do Trabalho.
“KARŌSHI” no Brasil? As decisões do Tribunal Superior do Trabalho e a superexploração do canavieiro
Authors: Horie Helen Yumi , Mandalozzo Silvana Souza Netto
Published: May 2024

Poucas são as investigações sobre “karōshi” (palavra que carrega o significado de “morte por excesso de trabalho”) na literatura brasileira. Para contribuir a preencher esta lacuna, o problema desta pesquisa e seu objetivo geral é explorar em que contexto o termo tem sido empregado nas decisões do Tribunal Superior do Trabalho. Este estudo é predominantemente jurisprudencial e bibliográfico. Utiliza-se o método dedutivo para análise das decisões judiciais a fim de explicar o fenômeno do “karōshi”. Constatou-se que o referido Tribunal emprega, na maioria das vezes, a palavra em contextos envolvendo o trabalhador canavieiro e discussões relacionadas a horas extras, adicional de insalubridade por exposição ao calor e doença profissional.
研究課題は、「過労死」という用語がブラジルの上級労働裁判所の判決においてどのような文脈で使用されているかを調査することである。この問題に関するブラジルの文脈での調査が不足していることを考慮して、この研究の主な目的は、「過労死」という言葉を含むブラジルの上級裁判所の判決を分析することである。 この主に法学および書誌学的な研究では、特に観察された現象を説明するために、演繹法を使用して司法判決を分析する。 前述の法廷は、ほとんどの場合、サトウキビ労働者や、時間外労働、暑さへの曝露による不健康な労働賃金、職業病などの議論に関連する文脈でこの言葉を使用していることに留意されたい。
Pensamiento Computacional: Habilidad Primordial para la Nueva Era
Authors: Bernal Párraga Augusto Paolo , Baquez Chávez Adriana Lissette , Hidalgo Jaen Nelly Guadalupe , Mera Alay Narcisa Alexandra , Velásquez Araujo Aminta Liliana
Published: May 2024

El pensamiento computacional interviene en todos los campos de la sociedad como un eje transversal, lo que lo convierte en un nuevo desafío para la educación centrada en el estudiante y en las habilidades que deben desarrollarse para la vida. Actualmente, el pensamiento computacional se considera una habilidad del siglo XXI que los estudiantes deben tener para desarrollar habilidades de resolución de problemas utilizando los principios informáticos [1]. La informática está presente en todos los aspectos de la  vida desde que el despertar por la mañana con un reloj despertador digital durante el día con la administración de aplicaciones, dispositivos móviles y su interacción con el Internet de las cosas, por esta razón es una parte intrínseca de los términos: ciencia, tecnología y sociedad. El pensamiento computacional se fundamenta en la disciplina de la informática y se integra en el conjunto de habilidades y procedimientos mentales y se puede percibir de forma precisa en el aula. Autores en investigaciones concluyen que la inclusión del pensamiento computacional podría darse desde los doce años de edad, pero las clases de computación, deben diferenciarse como la disciplina que facilita el uso de las computadoras aplicadas a tareas específicas en temáticas particulares en el tiempo destinado a la clase. Y aunque existen precedentes en el país con respecto a las propuestas para la capacitación de maestros en el campo tecnológico están orientadas a nivel básico como: el uso del correo electrónico y ofimática básica, desde 2015 no se han impartido cursos de capacitación para maestros de primaria y secundaria en temas de TIC, menos aún en el pensamiento computacional. Este trabajo se basa en una línea de base acerca del pensamiento computacional y una propuesta para su inclusión en el sistema de educación del Ecuador.
El Desempeño Académico como un Comportamiento en el Proceso de Enseñanza Aprendizaje
Authors: Rubiano Romero Sandra Soledad , Martínez Huertas Juan Carlos
Published: May 2024

El desempeño académico ha sido estudiado en los contextos educativos siempre ligado al rendimiento estudiantil, porque cuando el estudiante presenta bajas calificaciones se expone a diversas situaciones como la pérdida de materias, reprobación del grado escolar y hasta la deserción escolar. Sin embargo, etimológicamente, como señalan Pérez y Merino (2021) el desempeño es reconocido como el acto y la consecuencia de cumplir una obligación, realizar una actividad o dedicarse a una tarea. De allí, que en este artículo se busca profundizar en el concepto de “Desempeño Académico” como un comportamiento; es decir, como las acciones que realiza el estudiante para lograr sus metas académicas, y no como un resultado que lo relaciona con rendimiento estudiantil.  El trabajo se fundamenta en los aspectos teóricos de Navarro (2003), Tilano, Henao y Restrepo (2009), Quintero y Vallejo (2013), Erazo (2012), Rendón y Coronel (2019), Enríquez, Segura y Tovar (2013), Duque Vallejo y Rodríguez (2013), Palacios y Vásquez (2003), Reyes et al (2014). Para su realización se hizo una revisión documental, luego mediante una matriz crítica se contrastaron los alcances de cada autor, para posteriormente fundamentar una definición orientada a comprender el desempeño académico como un comportamiento. Los resultados indican que los autores, desarrollan planteamientos canalizados a reconocer el concepto “Desempeño académico”, como resultado del proceso de enseñanza, hasta el punto que algunos lo manejan como sinónimo de rendimiento académico, también se percibe que los autores no tienen un planteamiento claro sobre los componentes del concepto.
Eficacia y seguridad de la técnica americana modificada en un puerto de trabajo para colecistectomía laparoscópica
Authors: Rodríguez Eduin , Rangel Wilfredo , Mendoza Joselin , Turmero Luis , Varela Maibelith
Published: May 2024

Evaluar la eficacia y seguridad de la técnica americana modificada con un puerto de trabajo (TAMPT) en línea media para colecistectomía laparoscópica. Métodos: Se elaboró estudio prospectivo, comparativo, descriptivo de corte transversal, en pacientes con litiasis vesicular en el servicio de Cirugía General del Hospital Universitario de Caracas, durante enero-agosto 2022. Resultados: se realizaron 79 colecistectomía laparoscópicas, 34 por técnica americana y 45 con TAMPT. La TAMPT (40.26%) se ejecutó con intervalo de 30-60 min. La estancia hospitalaria promedio global fue 1,75 ± 0,87 días. El promedio global de dolor a las 24 horas fue de 4,43  0,68, según escala visual analógica (EVA). Los procedimientos realizados con TAMPT no presentaron complicaciones, con la técnica americana, se reportó dos: bilioma y lesión de víscera hueca, representando 2.54%. Conclusiones: La TAMPT, ha demostrado ser una técnica segura y eficaz como tratamiento quirúrgico de la litiasis vesicular, tanto para procedimientos electivos como de emergencia.
Varicela neonatal tardía: presentación en un paciente pediátrico
Authors: Planchet Jenny , Sánchez Ana , León Geraldine , Gutiérrez Liliana
Published: May 2024

La varicela es una infección poco frecuente durante la gestación, el riesgo para el feto y las manifestaciones clínicas, variarán en función del momento del embarazo en que se produce la infección materna, cuando la erupción maculopapular materna se produce entre los 5 días previos al parto y las 48 horas posteriores, se habla de varicela neonatal tardía. La clínica es grave, con afectación visceral (pulmonar, cerebral, hepática, hemorragias cutáneas, etc.) y un 30 % de los casos desarrollarán una varicela fulminante. Se presenta el caso de neonato masculino que consultó por lesiones en piel, tipo pápulas eritematosas y vesiculares pleomorfas, de distribución dispersa. Con evolución clínica tórpida, permaneció 24 horas en la institución, con franco deterioro respiratorio y neurológico, compatible con cuadro de varicela neonatal tardía fulminante.
Listeria monocytogenes y mecanismo de caballo de Troya a través de la barrera hematoencefálica
Authors: Andrade Pineda Ramón , Duque Prieto Andrés
Published: May 2024

Las infecciones del sistema nervioso central son potencialmente mortales, causadas por patógenos, como bacterias, virus y hongos. Para llegar hasta el cerebro, los microorganismos utilizan diversas vías y formas. Este patogeno es una bacteria grampositiva corta, flagelar e intracelular, con la capacidad de inducir su internalización en células fagocíticas (monocitos/macrófagos) y no fagocíticas (células endoteliales). Al infectar los macrófagos, estos microorganismos se valen de su capacidad de fijación, adhesión y migración transendotelial, para cruzar la barrera hematoencefálica, finalmente, generando meningitis bacteriana. En esta revisión describimos el mecanismo de caballo de Troya usado por Listeria monocytogenes para invadir el cerebro en el desarrollo de enfermedades infecciosas e incorporamos nuevos conocimientos sobre moléculas que intervienen en dicho mecanismo.
Alteraciones psiquiátricas en pacientes con antecedentes de infección por SARS-CoV-2
Authors: Lira Luis , Benítez Gustavo , Pulido María , Arias Sineed , Lira Miguel
Published: May 2024

Objetivo: Caracterizar los trastornos mentales de los pacientes consultantes del Servicio de Psiquiatría del Hospital Universitario de Caracas enero 2020 –enero 2021, que acudieron por primera vez y habían presentado infección por COVID-19 3 a 6 meses antes de consultar. Métodos: Se realizó un estudio observacional, descriptivo, retrospectivo, de corte transversal en pacientes que acudieron al Servicio de Psiquiatría del Hospital Universitario de Caracas para emergencia (por primera vez y sucesivas) por presentar patologías mentales durante y posterior a infección por COVID-19 durante el periodo enero 2020-enero 2021. Resultados: De 718 pacientes, 53 que acudieron con patologías mentales habían presentado infección previa por COVID-19 representando el 7,38%. Edad promedio 27-29 años (66,03 %). La mayoría del sexo femenino (71,69 %). El 77,35 % provenían del Distrito Capital; el 18,86 % del estado Miranda, siendo el estado civil predominante la soltería con 73,58 %; el 56,60 % estaban desempleados y el 79,24 % no poseían nivel de instrucción. En relación a los diagnósticos: trastorno depresivo mayor con síntomas ansiosos (30,18 %), trastorno depresivo (18,86 %), episodio maniforme (1,88 %) episodio psicótico agudo (18,86 %), trastorno de ansiedad generalizada (7,54 %), entre otros. Conclusión: Los síntomas psiquiátricos originados por infección por COVID-19 aparecen de forma más tardía y persisten después de la infección. Las mujeres manifestaron mayor riesgo de presentar síntomas relacionados con la salud mental; se asocia a alto nivel de vulnerabilidad a causa de la influencia de los roles sociales, ciclo reproductivo y mayor morbilidad psiquiátrica.
Peritonitis due to perforation of primary congenital duodenal diverticulum - a case report and review of the literature
Authors: Dang Nhu Thanh
Published: May 2024

Background: Duodenal diverticulum is a relatively common finding that can be incidentally found in upper gastrointestinal endoscopy in up to 20% of cases. Most duodenal diverticula are asymptomatic, and perforation of a duodenal diverticulum is extremely rare.

Case report: We present a case of spontaneous rupture of a duodenal diverticulum in a 41-year-old female diagnosed with perforated duodenal diverticulum intraoperatively. Resection of the perforated diverticulum was performed, and closure was done interruptedly in two layers. The patient recovered uneventfully.

Conclusion: Duodenal diverticulum perforation is a rare condition in which accurate preoperative diagnosis and treatment are challenging. Operative treatment with diverticulectomy and one or two-layer closure is the treatment of choice in most cases.