bluuebunny/crossref_metadata_2025 huggingface dataset:
CEMARAN BAHAN KIMIA BERBAHAYA UNTUK MENINGKATKAN KUALITAS KESEHATAN MASYARAKAT INDONESIA
Authors: Wahjudi Teguh , Mustika Arifa , Haryono Nanang
Published: June 2020

The purpose of science and technology program for the public identification of hazardous food materials from contaminated drugs and hazardous chemicals on youth and mothers PKK Mojokerto regency through testing the content of formalin in foodstuﬀs, especially salted fish, wet fish, shrimp, chicken, raw tofu, wet noodles, meatballs Using formalin main reagent. Science and technology for the community to be transferred is a method of spot test. Food is a necessity for all living things including humans. Food is needed to obtain energy used for daily activities. In general, food is only able to survive within a few days or a few hours until the meal is no longer consumable and should be discarded. Partners in this program are youth and mothers PKK Kelurahan Sawahan, Mojokari District Mojokerto District. Each group consists of five cadres. This method is the application of existing chemical analysis methods for determination of formalin content, borax, and hazardous dyes. Spot test method is chemical analysis method by using reagent. This method has the features of fast, cheap, sure and does not require complicated equipment and can be done anytime and anywhere. The working principle is to add liquid (reagent) to the foodstuﬀs that are suspected to use the material under investigation, with the final result of a distinctive color change. Formalin main reagent is one type of formalin tester kit tester.AbstrakTujuan program IbM identiﬁkasi bahan berbahaya makanan dari cemaran obat dan bahan kimia berbahaya pada karang taruna dan ibu PKK Kabupaten Mojokerto melalui pengujian kandungan formalin pada bahan makanan khususnya ikan asin, ikan basah/udang, ayam potong, tahu mentah, mi basah, bakso menggunakan FMR (formalin main reagent). Iptek bagi masyarakat yang akan di transfer adalah metode spot test. Makanan merupakan kebutuhan bagi semua mahluk hidup termasuk manusia. Makanan dibutuhkan untuk memperoleh energi yang digunakan untuk beraktiﬁtas sehari-hari. Secara umum makanan hanya mampu bertahan dalam waktu beberapa hari atau beberapa jam sampai makan tidak lagi dapat dikonsumsi sehingga harus dibuang. Mitra dalam program IbM ini adalah Karangtaruna dan Ibu PKK Kelurahan Sawahan, Kecamatan Mojosari Kabupaten Mojokerto. Masing-masing kelompok terdiri atas lima kader. Metode ini adalah penerapan metode analisa kimia yang sudah ada untuk penetapan kandungan formalin, borak, dan zat pewarna berbahaya. Metode spot test yaitu metode analisa kimia dengan menggunakan reagent kit (kit tester). Metode ini mempunyai keistimewaan antara lain cepat, murah, pasti dan tidak memerlukan peralatan yang rumit dan dapat dilakukan kapanpun dan dimanapun. Prinsip kerjanya adalah dengan menambahkan cairan (reagent) pada bahan makanan yang diduga menggunakan bahan yang diselidiki, dengan hasil akhir terjadinya perubahan warna khas. FMR (formalin main reagent) merupakan salah satu jenis kit tester kandungan formalin.
PENGAJARAN KOMPETENSI BAHASA INGGRIS UNTUK SEKOLAH MENENGAH KEJURUAN
Authors: Handoko Putut , Parawiradiredja Sanhari , Santoso Budi
Published: June 2020

Pengabdian masyarakat ini dilakukan untuk mengembangkan kompetensi bahasa siswa di kalangan siswa Sekolah Menengah Kejuruan. Siswa yang dipilih adalah siswa kelas XII dengan pertimbangan mereka akan menyelesaikan proses belajar di sekolah dan terjun ke masyarakat dengan memanfaatkan ketrampilan yang dimiliki. Mitra pengabdian pada masyarakat adalah Siswa Kelas XII SMK Mahardhika Surabaya. Dari analisis situasi yang dilakukan nampak bahwa permasalahan yang dihadapi mitra adalah siswa kelas adalah kurangnya motivasi belajar karena anggapan dasar bahwa Bahasa Inggris adalah mata pelajaran yang sulit. Dari pretest yang dilakukan ada beberapa materi dasar yang sulit dipahami khususnya reading, kurang mengerti topic, main idea, dan menjawab WH Question serta kurang fokusnya siswa dalam mengikuti proses pembelajaran. Pengajaran menggunakan pendekatan komunikasi persuasif motivasional, diadakan tes awal, pengajaran topic, main idea, dan WH Question dengan pengayaan materi. Setelah proses treatment tersebut diadakan tes evaluasi (post test) yang menampakkan hasil bahwa siswa mulai termotivasi belajar Bahasa Inggris, fokus dan mandiri denganhasil tes rata-rata nilai bagus. Kontribusi dan manfaat yang diperoleh khalayak sasaran adalah motivasi belajar Reading, fokus dan mandiri dalam belajar bahasa inggris.
PEMBUATAN DAN DIGITALISASI BATIK TULIS MADURA PADA UKM BATIK BANGKALAN
Authors: Siradjuddin Indah Agustien , Sophan M. Kautsar , Kurniawati Arik , Triwahyuningrum Rima
Published: June 2020

Batik Madura dikenal akan jenis batik tulis Madura yang memiliki motif batik dan warna batik yang unik. Keseluruhan produksi batik tulis Madura ini dilakukan secara manual, mulai dari desain batik, menggambar batik pada kain, mencanting, fiksasi, pewarnaan, dan lain-lain. Proses manual inilah yang tetap menjaga keaslian batik tulis Madura. Hanya saja, kain batik yang dihasilkan pada batik tulis Madura ini, tidak menghasilkan pola yang simetris ketika kain batik dibuat menjadi sebuah pakaian. Motif-motif yang terdapat pada pakaian yang berasal dari kain batik tulis Madura, tidak membentuk pola yang simetris. Oleh karena itu diperlukan upaya agar motif-motif yang dibuat oleh pengrajin batik, dapat membentuk pola simetris pada suatu pakaian. Kegiatan pengabdian yang diusulkan adalah pembuatan motif batik tulis Madura, agar pakaian yang dihasilkan menampilkan pola simetris, dengan bantuan perangkat lunak. Tahap pertama yang dilakukan adalah pembuatan mal atau template pakaian yang akan dibuat, penyusunan mal ini pada desain kain batik, penyusunan motif-motif batik pada kain sehingga sesuai dengan mal pakaian yang telah ada.
PENERAPAN PAKAN SUPLEMEN BLOK UKKMB DAN JERAMI FERMENTASI PADA PKM KELOMPOK TANI TERNAK SAPI BALI DI DESA LEMPANG KECAMATAN TANETE RIAJA KABUPATEN BARRU
Authors: Abustam Effendi , Yusuf Muhammad , Said Muhammad Irfan
Published: June 2020

PKM Livestock Farmers Group in Lempang Village Barru District has been conducted on two partnersnamely Sikapa Livestock Group and Livestock Group Padaelo in Tanete Riaja District which lasts from July to September 2018. The technology applied by the team is the manufacture of UKKMB blocks feed supplement and probiotic fermentation straw on. This activity aims to improve the skills of members of livestock groups in the application of livestock technology, especially in the manufacture of feed. The productivity of Bali cattle needs to be improved through the provision of quality feed as one of the problems found. The implementation method is in the form of training (theory and practicum), action review, mentoring and application of feed products to Bali cattle in a cage. Making modified feed supplements in the form of UMMB into Urea Water Collagen Coconut Multinutrient Block (UKKMB) and probiotic fermented rice straw is the main product tried in Bali cattle at home. The provision of block supplement feed in Bali cattle increases appetite and feed consumption. The results of the activity showed that UKKMB and probiotic fermented rice straw could solve the problem of the availability of feed in the cage and the increase in cattle weight.
PEMBERDAYAAN MASYARAKAT MELALUI PEMBUDIDAYAAN DAN PENGOLAHAN MARKISAH BERBASIS POTENSI DAERAH UNTUK MENINGKATKAN PENDAPATAN KELUARGA
Authors: Jasminarni Jasminarni , Suandi Suandi , Dan Evita Trias Novita
Published: June 2020

Tujuan kegiatan KKN-PPM ini adalah untuk pemberdayaan masyarakat melalui pembudidayaan dan pengolahan markisah berbasis potensi daerah untuk meningkatkan pendapatan keluarga. KKN merupakan mata kuliah wajib di universitas jambi yang harus diikuti oleh setiap mahasiswa sebelum melaksanakan ujian akhir (skripsi) hal ini tertuang pada Peraturan Rektor Nomor: 1223/UN 21/DT/2013, tanggal 19 November 2013. Pelaksanaan program KKN-PPM menggunakan metoda utama berupa pelatihan, demonstrasi dan demplot kepada kelompok sasaran. Mahasiswa yang sudah diberi pembekalan akan mendampingi kelompok sasaran selama pelatihan dan pelaksanaan KKN-PPM. Langkah-langkah operasional yang akan dilakukan selama program KKN-PPM secara terinci adalah sebagai berikut pemilihan anggota masyarakat yang akan dibina pada dua desa, analisispengetahuan masyarakat tentang tanaman markisah dan pengenalan pada mereka usaha budidaya dan pengolahan markisah, pemberian pelatihan manajemen pada masyarakat membuat, mengatur dan menjaga unit budidaya dan pengolahan markisah, pelatihan dan demontrasi pembuatan unit budidaya dan pengolahan markisah dengan memanfaatkan lahan pekarangan yang dilakukan oleh mahasiswa didampingi Dosen Pembimbing Lapangan (DPL). Target kegiatan KKN-PPM adalah metode dan produk: (1) Perbaikan teknik budidaya markisah sehingga dapat menghasilkan produksi yang optimum, sehingga terjadinya peningkatan pendapatan masyarakat. (2) Memanfaatkan lahan pekarangan sebagai lahan budidaya markisah, sehingga dapat dimanfaatkan sebagai bahanbaku pengolahan panganan yang dapat menambah nilai jual markisah yang dibudidayakan. (3) Terjadinya perbaikan sistem budidaya markisah tanpa mengikuti persyaratan budidaya menjadi mengikuti syarat yang semestinya. (4) Pengolahan aneka panganan berbahan baku markisah sebagai oleh-oleh sehingga dapat menambah pendapatan masyarakat. (5) Terjadinya peningkatan partisifasi masyarakat melalui pembinaan yang dilakukan dan pelatihan pembuatan panganan berbahan baku markisah seperti dodol markisah dan sirup markisah.. Kegiatan KKN-PPM akan dilaksanakan di dua desa di Kecamatan Keliling Danau yaitu Desa Koto Baru dan Desa Koto Agung. Metode kegiatan yang dilakukan dalam pemberdayaan kelompok sasaran adalah metode partisipasif dan aksi yang melibatkan kelompok sasaran dibagi dalam 2 kelompok pengembangan budidaya tanaman markisah dan 2 kelompok pengolahan markisah menjadi berbagai produk penganan. Selainitu, masyarakat secara umum diikutkan dalam kegiatan ini. Mahasiswa bertindak sebagai fasilisator. Materi yang diberikan melalui pembelajaran orang dewasa (andragogi), dengan rasio 30% teori dan 70% praktek.
OPTIMALISASI POS UPAYA KESEHATAN KERJA PADA TENAGA KERJA SEKTOR INFORMAL DI WILAYAH KERJA PUSKESMAS WARU, KABUPATEN SIDOARJO
Authors: Hidayat Sho’im , Martiana Tri , Alayyannur Putri Ayuni
Published: June 2020

Tahun 2011, terdapat 99 industri kecil di Kecamatan Waru yang merupakan wilayah kerja dari Puskesmas Waru. Jumlah tersebut merupakan jumlah terbanyak di Kabupaten Sidoarjo. Hal ini menunjukkan bahwa kelompok industri kecil yang menjadi sasaran program Pos Upaya Kesehatan Kerja (UKK) di wilayah Puskesmas Waru merupakan sasaran yang terbanyak pula di Kabupaten Sidoarjo. Penelitian oleh Wignjosoebroto, Arief dan Dwi tahun 2006 pada salah satu industri metal di daerah Ngingas, Waru, Sidoarjo menunjukkan bahwa terdapat 2 kecelakaan kerja di 2002, 3 kecelakaan kerja di 2003, dan 2 kecelakaan kerja di 2004. Optimalisasi Pos UKK dilakukan dengan beberapa kegiatan yaitu pemberdayaan petugas Puskesmas di Kabupaten Sidoarjo; brainstorming antara petugas dan sektor informal; pemberdayaan tenaga kerja sektor informal; mapping hazarddi tempat kerja; dan pembuatan program K3 pada sektor informal. Kegiatan pemberdayaan petugas Puskesmas meliputi workshop yang diikuti oleh seluruh petugas Puskesmas di wilayah kerja Dinas Kesehatan Kabupaten Sidoarjo yang memiliki hak dan tanggung jawab terkait kesehatan dan keselamatan kerja. Brainstorming antara petugas dan sektor informal dilakukan untuk mengidentifikasi masalah yang terjadi dan mendapatkan kesepakatan tindak lanjutnya. Workshop pemberdayaan tenaga kerja sektor informal diberikan materi K3 secara umum, yang disampaikan oleh petugas Puskesmas yang sudah mengikuti workshop di Kabupaten. Mapping hazard di tempat kerja dilakukan untuk memudahkan pengelompokan hazard fisik, kimia, biologi, psikologi, dan ergonomi. Program K3 yang diusulkan pada anggaran daerah yaitu khusus untuk tenaga kerja sektorinformal. Sektor informal membutuhkan kehadiran negara dalam mengatasi kesehatan dan keselamatan kerjanya. Pembuatan program K3 ini juga dibarengi dengan pembuatan anggaran dana.
PEMBERDAYAAN UMKM UDANG KETAK PADA PENGOLAHAN UDANG KETAK DI KECAMATAN KUALA JAMBI TANJABTIM PROPINSI JAMBI
Authors: Monica Metha , Setyaji Hajar , Suryanto Suryanto
Published: June 2020

Daerah pantai yang sering disebut sebagai wilayah pesisir merupakan daerah yang sangat spesifik seperti Kecamatan Kuala Jambi, karena daerah ini merupakan daerah yang berada di perbatasan antara pengaruh daratan dan lautan. Mengingat posisi geografisnya, daerah pantai merupakan daerah penghubung antara daratan dan lautan sangat strategis sebagai usaha pengembangan sektor perikanan spesifik lokal (Juarini,2002). Salah satu usaha pengembangan sektor perikanan spesifik lokal khususnya di Propinsi Jambi adalah usaha agribisnis udang ketak. Kegiatan ini dilakukan dari Bulan Mei - November tahun 2017. Mitra yang dilibatkan adalah 2 (dua) Kelompok UMKM, UMKM Bangau yang berada di Kelurahan Majelis Hidayah di ketuai oleh Ridho Ardiansyah dan UMKM Elang yang berada di Kelurahan Kampung Laut diketuai oleh Muamar. Kedua UMKM berada di Kecamatan Kuala Jambi Kabupaten Tanjabtim. Pelaksanaan Kegiatan dilakukan dengan 5 (lima) tahapan yaitupersiapan, penyuluhan, kegiatan lapangan, pembinaan dan penyusunan laporan. Permasalahan Mitra adalah Sumberdaya Manusia, Modal, Bahan Baku dan Penguasaan teknologi tentang pengolahan udang ketak. Tujuan yang ingin dicapai dari kegiatan ini adalah : a. Memotivasi dan mengembangkan kemampuan teknis penerapan teknologi sederhana pengolahan udang ketak/ mantis shrimps pada usaha mikro, kecil dan menengah (UMKM) udang ketak yaitu Pengolahan udang ketak yang sudah diberi sambal tomat dan terasi serta dikemas plastik dan divakum; b. Mengembangkan usaha olahan udang ketak yang siap dijual; c. Menambah pendapatan usaha mikro, kecil dan menengah (UMKM) udang ketak di Kecamatan Kuala Jambi d. Adanya kerjasama antara Perguruan Tinggi dan UMKM. Sasaran yang ingin dicapai yaitu : Penerapan teknologi sederhana dengan cara pengolahan udang ketak diberi bumbu, sambal nenas dan terasi, dikemas vakum dan ada izin IRT serta siap dijualsehingga meningkatkan nilai jual udang ketak secara lokal (Jambi, Jakarta, Yogyakarta, Batam) . Hasil luaran yang dicapai adalah Penyerahan barang untuk pengolahan udang ketak berupa food processor, gas 3 kg, vacuum sealer, freezer, dandang, kompor gas dan selang, nampan dan centong, pelatihan pengolahan udang ketak mulai dari buat sambal tomat dan terasi serta pengemasan udang ketak dengan plastik dan divakum, pengurusan izin P-IRT. Kesimpulan Penyerahan alat yang digunakan untuk pengolahan udang ketak berupa food processor,gas 3 kg, vacuum sealer, freezer, dandang, kompor gas dan selang, nampan dan centong, Pelatihan pengolahan udang ketak mulai dari pembuatan sambal sampai pengemas udang ketak, Pengurusan Izin P-IRT sudah sampai BPOM Propinsi Jambi dengan Nama Hidayah (UMKM Bangau) dan Nama Mr. J. (UMKM Elang)
Targeted Therapies For Treatment of Lung Cancer – Recent Advances
Authors: Foziya Khan  , S.S. Sisodia
Published: June 2020

In both men and women, Lung cancer is the number one cause of cancer-related death. The disorder is especially difficult to detect, and often develops for elderly patients at an advanced stage. Within a year of treatment, more than half of those diagnosed with lung cancer die and 5- year survival is less than 18%. Majority of all lung cancer cases are attributed to Non Small Cell Lung Cancer. Significant advancements in research and diagnosis over the past 10 years have though, culminated in the first improvements made in lung cancer survival. New developments in lung cancer’s cellular pathogenesis and biological activity have culminated in the advancement of rationally developed approaches for early detection, prevention, and treatment of this illness. There are currently several novel treatments in clinical practice, including those that target actionable mutations and more recently immunotherapy. This review will outline developments and emerging debates in lung cancer treatment.
YOUTUBER MIRIM EM BELÉM: o consumo que encanta
Authors: Leão Danuta de Cássia , Oliveira Ivana Claudia Guimarães
Published: June 2020

O objetivo deste trabalho é pensar como se dão as produções e interações das crianças com a plataforma digital YouTube, em análise sobretudo os que dizem respeito as relações mercadológicas e comunicacionais deste “eu” no mundo digital. Assim, este artigo analisa a criança enquanto sujeito social e sua relação com a mídia YouTube. A análise foi feita a partir da revisão bibliográfica para se entender o YouTube e o consumo digital e a partir do conteúdo de canais foi possível entender a dinâmica da linguagem espetacular produzida por eles, para cativar suas audiências, a fim de compreender a importância do lugar que a infância ocupa na contemporaneidade digital.

 

PALAVRAS-CHAVE: Infância; YouTuber mirim; Consumo; Espetáculo; Digital

 

 

ABSTRACT

This study aims to think how children productions and interactions happen in the YouTube digital platform, especially those concerning the marketing and communicational relations about this “self” in the digital world. Thus, this study analyzes the child as a social subject and his relationship with YouTube platform. The analysis is made with the literature review to understand YouTube and digital consumption and starting from the channels content it was possible to understand the dynamics of the spectacular language produced by them, to captivate their audiences, in order to understand the importance of the childhood role occupies in the digital contemporary.

 

KEYWORDS: Childhood; Child YouTuber; Consumption; Spectacle; Digital

 

 

RESUMEN

El objetivo de este artículo es pensar en cómo las producciones e interacciones de los niños con la plataforma digital YouTube, especialmente aquellas relacionadas con las relaciones de marketing y comunicación de este yo en el mundo digital. Por lo tanto, este artículo analiza al niño como sujeto social y su relación con los medios de YouTube. El análisis se realizó a partir de la revisión de la literatura para comprender YouTube y el consumo digital, y del contenido de los canales fue posible comprender la dinámica del lenguaje espectacular producido por ellos, cautivar a sus audiencias para comprender la importancia del lugar. que la infancia ocupa en lo digital contemporáneo.

 PALABRAS CLAVE: Infancia; YouTuber niño; Consumo; Mostrar Digital
The Development of Thermodynamics Law Experiment Media Based on IoT: Laboratory Activities Through Science Problem Solving for Gifted Young Scientists
Authors: Liana Yeni Rima , Linuwih S , Sulhadi S
Published: June 2020

In this research, thermodynamics law experiment media based on IoT was developed and tested. The purpose was to assess the effectiveness of the IoT-based thermodynamic law experiment media through a problem-based learning approach and laboratory activities using science problem solving for talented young scientists. This research was conducted at SMA 2 Batang. This study using the ADDIE approach model. The development steps are: (1) analyzing curriculum requirements and demands in 2013, (2) designing and manufacturing, (3) developing media, (4) limited through small-scale tests, expert testing, tested on professional physics teachers and student grade XI sciences, (5) evaluated to get feedback in the form of comments and suggestions. This media is equipped with an LCD display to read of temperature, electric current, and electrical voltage in real-time which is integrated with the the Thingspeak application on every student’s android phone. This media is easily assembled, based on digital, equipped with manuals and student worksheets. The validation results from the media experts 90.20% (Very Good), the results of the validation from the material experts 91.50% (Very Good), and the results of the physics teacher’s responses covering all aspects of the material and multimedia 93.00% (Very Good). The results of the validation show that thermodynamics law experiment media based on IoT is appropriate to be used as a media for learning activities in the thermodynamics law material laboratory.
Dr Siddiq Fadzil dan Derap Perjuangannya
Authors: Amir Ahmad Nabil
Published: June 2020

Kertas ini menelaah buku Melayu dan Islam: Martabat Umat dan Daulat Rakyat karya Dr Siddiq Fadzil. Setelah diluncurkan pada 25 Jun 2012 di Hotel De Palma, Ampang, buku Melayu dan Islam: Martabat Umat dan Daulat Rakyat karya Dr Siddiq Fadzil terus diangkat dan “siap ditanggapi” oleh khalayak pembaca dan intelek. Dr Siddiq lahir di kalangan pemikir dan kelompok pembaharu di tanah air; dan merupakan aktivis dan pemimpin Islam yang besar yang menonjol dalam kegiatan intelek dan budaya yang luas. Beliau merupakan penggerak penting gerakan PKPIM (Persatuan Kebangsaan Pelajar Islam Malaysia), ABIM (Angkatan Belia Islam Malaysia) dan WADAH (Wadah Pencerdasan Umat Malaysia) dan telah bergelut dalam perjuangan bangsa sejak empat dekad yang lampau. Artikel ini cuba merumuskan sumbangannya dalam buku Melayu dan Islam ini sebagai suatu koreksi budaya dalam mengangkat diskusi tentang tradisi dan ciri budaya yang signifikan di kepulauan Melayu-Indonesia yang berakar dengan nilai rasionalisme dan humanisme Islam yang kental dan faham-faham pemikiran yang ideal yang telah mengangkat dan mempertahankan nilai kebudayaan dan peradabannya sejak masuknya Islam ke nusantara.
Rare cases of gas poisoning in the practice of forensic medicine
Authors: Majdanik Sławomir , Potocka-Banaś Barbara , Łabęcka Marzena , Semeniuk Urszula , Borowiak Krzysztof
Published: June 2020

Cases of poisoning with gases other than carbon monoxide are rarely reported in forensic medicine. Usually they are associated with an accident, suicidal intoxication, or recreational inhalation to obtain psychoactive effects. The paper presents 2 cases of poisoning with an air freshener aerosol and argon. Both cases were confirmed after confronting the results of post-mortem examination, additional tests, and the detailed circumstances of the incidents. These cases deserve attention because of both the clinical and scientific aspects.
Evaluation of women’s quality of life after breast reconstruction surgery
Authors: Stanisz Marta , Kolak Ewelina , Branecka-Woźniak Dorota , Robaszkiewicz-Bouakaz Renata , Ciepiela Przemysław , Kurzawa Rafał
Published: June 2020

Introduction: Breast cancer is the most common malignancy among women, and is usually treated surgically. Mastectomy has a great influence on the mental and physical condition of women. Breast reconstruction offers them a chance to improve their quality of life (QOL) and self-image.

The main aim of the study was to gain knowledge about the impact of breast reconstruction on the QOL of women following mastectomy, and an analysis of the QOL after breast reconstruction, in the context of prosthesis effect assessment.

Materials and methods: The study comprised 100 women following breast reconstructive surgery involved in 1 of the 7 “Amazon Clubs” (post-mastectomy women’s associations) in the West Pomeranian Voivodeship, northwest Poland. The study was based on the author’s questionnaire, and a shortened standardized version of the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire. Statistical calculations were performed with StatSoft Statistica v10 software, adopting a significance level of p < 0.05.

Results: The women who decided to have breast reconstruction surgery, noticed improved well-being (67%) and experienced an increase in self-confidence (61%). The vast majority of the patients surveyed (93%) were satisfied with the effect of the prosthesis. Statistically significant differences in QOL were observed in the following spheres: rest and sleep, work capacity, negative feelings, and financial resources (p < 0.05) in relation to the evaluation of the prosthesis effect.

Conclusions: 1. Breast reconstruction has a positive influence on improvements in well-being, increasing self-esteem, and the assessment of a more attractive appearance in women of all ages. 2. Breast reconstruction surgery has a positive impact on QOL and health in the physical, psychological, and environmental domains, especially in the women who are satisfied with the effects of the surgery. 3. A negative assessment of the breast reconstruction effect has an adverse influence on QOL. Identifying the factors affecting dissatisfaction with the post-operative outcome is crucial for a complete understanding of the subject, and for implementing measures aimed at improving the QOL of these women.
Nonstructural versus structural bone grafting in the treatment of lumbar tuberculosis: a retrospective cohort study
Authors: Zhao Zenghui , Li Jianxiao , Peng Qiqi , Zhu Yong , Luo Wei , Du Xing , Ou Yunsheng
Published: June 2020

[Background] Various bone grafting have been reported to achieve anterior column support and bone fusion after one stage posterior debridement in the treatment of lumbar tuberculosis. However, nonstructural bone grafting has been rarely studied. This study aimed to compare the efficacy of nonstructural bone grafting versus structural bone grafting in the treatment of lumbar tuberculosis.[Patients and methods] We retrospectively reviewed patients with nonstructural (n=27) and structural (n=22) bone grafting after single-stage posterior debridement and instrumentation for lumbar tuberculosis with at least 24 months of follow-up. Plain radiographs, magnetic resonance imaging, computed tomography scans, and health-related outcomes (e.g. Visual Analog Scale for back pain, the Oswestry Disability Index) were collected before surgery and at follow-up. [Results] Both nonstructural and structural bone grafting were associated with significant improvements in the quality of life parameters, the laboratory tests and the Cobb angle of local kyphosis. A slight loss of Cobb angle correction was observed in two groups. Nonstructural bone grafting resulted in the significantly less operation duration, blood loss and lower bone fusion rate than structural bone grafting group. There were three complications in the nonstructural bone grafting and four complications in the structural bone grafting group, with no significant difference between two groups.[Conclusions] Nonstructural bone grafting can achieve anterior column support with less surgical trauma and simpler surgical procedure than structural bone grafting, but the lower rate of grafted bone fusion should be taken into consideration when choosing nonstructural bone grafting.
The impact of lower extremity neuropathy and artery disease on gait characteristics in type 2 diabetic individuals
Authors: Xu Lei , Zeng Hui , Shen Wenqi , Zhao Jungong , Shao Mingzhe , Zhao Jun , Chen Hua , Hu Hai , Esser Patrick , Dawes Helen , Liu Fang
Published: June 2020

Background

It is generally believed that gait characteristics of diabetic neuropathic patients differ from non-diabetic ones. However, it is still unclear whether these changes during walking could also be extended for different conditions of type 2 diabetes mellitus (T2DM), especially diabetic individuals with lower extremity complications.
Methods

In this investigation, gait was examined among 1861 participants with or without T2DM from three study centers. Subjects with NGT(normal glucose tolerance) and IGT (impaired glucose tolerance) were taken as control groups, patients with T2DM were divided into 4 groups: DM (no chronic complications), DPN (DM complicated with diabetic peripheral neuropathy), LEAD (DM complicated with lower extremity artery disease) and DPN + LEAD. Analyses of variance were employed to verify possible differences of gait parameters between these groups.
Results

Results showed lowered cadence, increased step time and decreased walking speed in diabetes with lower extremity neural and/or vascular complications (all p < 0.05). Increased duty factor_double stance was displayed in participants with LEAD alone (32.51%, p < 0.05). And the results displayed lower SDA (1.32 vs. 1.57, p < 0.01) and SDB (0.38 vs. 0.51, p < 0.01) of subjects with both DPN and LEAD. All these indicated the subjects with diabetic lower extremity complications showed much more conservative gait pattern. Stepwise multivariate regression models showed that independent variables were sex, age and leg length (p < 0.01). While, VPT was listed as significant independent predictor of cadence, step time, SDA and SDB (p < 0.05). And ABI was documented as significant independent predictor of stride length, duty-factor_Double stance, SDA and SDB (p < 0.05). Binary logistic regression analysis revealed a significant positive association between decreased stride length and the lowest ABI group (OR = 112.19, 95% CI: 3.11- 4040.13, p = 0.01). ROC analysis showed a significant discriminatory power of step time for occurrence of DPN. The AUC value was 0.752 (95% CI: 0.721–0.782, p < 0.01) .
Conclusions

In total, the cut-off point was 526.13 ms for predicting DPN. Maybe, this non-invasive and non-irritating gait examination could be an alternative measurement that could help distinguish diabetic neuropathy conveniently.
¿Does ACL reconstruction have any influence in meniscal repair?. Sports return, quality of life and failure rate. 2-12 years follow up.
Authors: Rodríguez-Roiz Juan Miguel , Sastre-Solsona Sergi , Popescu Dragos , Burillo Jordi Montañana , Aleu Andrés Combalia
Published: June 2020

Objective: few studies have approach inlong term follow up of meniscal repair at amateur level, specially studying variables as quality of life and failure rate. We study mediumlongterm clinical results in amateur sports patients, that have required meniscal sutures at our centre, with or without ACL reconstruction. We evaluate the objective function of the knee, as well as patients’ return to sports activities, quality of life and the rate of failed repair and study of the possible reasons. Methods: this was an observational retrospective study, 92 patients were assesed who required a meniscal repair in our centre from april 2007 until april 2018, who regularly perform amateur sports activities (Tegner 4 to 7), minimum follow-up period of 2 years, divided into 2 groups: group 1 isolated meniscal suture (43 cases), group 2 associated to ACL reconstruction (49 cases). Each patient made this tests in 2019: Lysholm andTegner (validated for spanish) before the meniscal injury and after the surgical procedure, motivation to return to sports activity (Likert scale with 3 items: low, regular or high), quality of life (through SF-12 test). Results: high return to amateur sports rate (92%), which was even higher in the isolated meniscal repair group in comparison to the group with associated ACL, at a minimun follow-up of 2 years. We have not found statistically significant differences between sports return and: age, gender, injured meniscus, chondral injuries, preoperative Tegner score, or motivation. No significant differences in physical or mental health fields between both groups. Meniscal repair failed in 12 patients (13%,)and they finally required a partial meniscectomy, as complications just one debridement for superficial infection of ACL donor zone. Higher rate of failure in isolated bucket-handle tear injuries (p<0.0062). No statistically significant association were found between the other variables studied. Conclusions: 92% of sports return and low meniscal repair failure rate, even lower when is associated to ACL reconstruction.
Emergency contraception use in young Norwegian women The role of social background, sexual history, and risk behaviors
Authors: Kvalem Ingela Lundin , Mannsverk Ingrid Grov , NILSEN WENDY
Published: June 2020

Background

Emergency contraception use has received little attention compared to other contraceptives (e.g., condoms), despite increased use in most western countries. The present study aims to examine individual risk behavior and social characteristics of adolescent emergency contraception use of women in late adolescence, a key developmental stage for risky sexual behaviors.
Methods

A total of 214 young women (ages 18–20) from the community-based “Tracking Opportunities and Problems in Childhood and Adolescence” study self-reported their contraceptive use, sexual history (debut age, number of partners, sexually transmitted infections, abortions), risk behaviors (externalizing behavior, alcohol use), and social factors (living arrangements, educational status). Their mothers reported the young women’s socioeconomic background (family economy, education). Differences were tested between groups that had never used emergency contraception, used it once, and used it many times.
Results

Over half of the sample had used emergency contraception. Emergency contraception users were a heterogeneous group. Multi-time users of emergency contraception reported to have had more unprotected drunk sex than those having used emergency contraception once or never, and they were younger when they first had sexual intercourse and had more sexual partners (both in their lifetime and in the last year) than those who had never used emergency contraception. Emergency contraception use did not differ in relation to social background, regular contraception use, or consequences of unprotected sex.
Conclusions

This is one of the few studies examining characteristics of groups based on different types of emergency contraception use history in a community sample of women in their late adolescence. Findings revealed significant differences in the profiles of multi-time, one-time, and non-users of emergency contraception in some factors, but no difference between groups based on regular contraception use. The findings can provide researchers, practitioners, and policy makers with a more nuanced perspective of emergency contraception users, thus strengthening counseling and planning prevention efforts.
A survey of the organization, preparation and workload of the medical aid teams sent to Wuhan in China during Covid-19 epidemic
Authors: Zhong Jing , Sun Xingfeng , Sun Minli , Liang Peng , Ge Feng , Fei Min , Ling Xiaomin , Liang Chao , Luo Zhe , Miao Changhong
Published: June 2020

Background: The 2020 Covid-19 epidemic challenged China’s mechanisms for public health team mobilization to control outbreaks. As of March 8th, 346 non-military Medical Aid Teams (MATs) and 42,600 team members have been sent to Hubei Province from other regions in China. This study aims to review the organization and perspectives of the MATs sent to Wuhan during Covid-19 epidemic.Methods: The organization, preparation and workload of doctors and nurses in each MAT were reviewed via a Web-based survey filled by the MATs leaders. The perspectives of the MATs members were investigated via an independent Web-based survey. Results were reported as numbers and percent. The qualitative data was analyzed using thematic content analysis.Results: The leaders of nine MATs from six provinces or municipality participated in the first survey. In the second survey, 512 valid questionnaires including 142 doctors and 370 nurses were collected. The average number of members in a MAT was 138. Each MAT included pulmonary physicians and ICU doctors. The percentage of nurses varied from 60% to 80%. The staffing of MATs was suggested to be optimized. Before going to Wuhan, 32% of participants are members of the Medical Emergency Team in hospital. 91% of the MAT members received pre-service training. Two most important trainings were nosocomial infection control and self-protective measures. The average stay of MATs in Wuhan was 51 days. The lack of medical materials supply was considered as the most important factor that negatively affected organizational MATs efficiency. Psychological counseling for the members of MATs needs to be strengthened.Conclusion: The MATs sent to Wuhan from tertiary hospitals in other regions in China were organized and prepared to fight Covid-19 epidemic. The staffing of MATs needs to be optimized. The lack of medical materials supply was considered as the most important factor that negatively affected organizational MATs efficiency. Psychological counseling was considered to be in need of strengthening.
Homocysteine Promotes Migration of Adventitial Fibroblasts via Angiotensin II type 1 Receptor Activation to Aggravate Atherosclerosis
Authors: Zhu Zhibo , Hao Xiangyu , Li Tianxiang , Guo Jianqiang
Published: June 2020

BackgroundHyperhomocysteinemia (HHcy) is an independent risk factor for atherosclerosis. However, the mechanisms of HHcy-induced arteriosclerosis are largely unknown. Objective:To clarify the effect of Hcy on adventitial fibroblasts (AFs) and its relation with angiotensin II type 1 receptor (AT1R).Method:The apolipoprotein E gene-deficient mice (Apoe−/−) were used as the murine model for atherosclerosis. HHcy was induced and treated by feeding them 1.5% methionine and telmisartan (gavage 10 mg/kg/d) for 12 weeks, respectively. The AFs and HEK293A cells transfected with the AT1R plasmid were used to investigate the interaction between Hcy and AT1R. All data were expressed as mean ± SEM. The data were analyzed by one-way ANOVA or repeated measurement ANOVA.Results:HHcy aggravated the plaque area of the aortic root and increased the expression of IL-6, MCP-1, and the macrophage marker Mac3 in the plaque and adventitia of the aorta, whereas telmisartan improved this effect. Hyperhomocysteinemia induced the occurrence of the AFs marker protein ER-TR7 in the plaque and the entire layer of the aorta, whereas telmisartan also improved this effect, indicating that hyperhomocysteinemia induced AFs migration and that AT1R mediated this process. Hcy increased the production of AFs H2O2, ROS, and IL-6 of AFs, indicating that Hcy activated the oxidative stress and inflammatory reactions, which may induce cell migration. The subsequent scratch and transwell experiments confirmed that Hcy induced the AFs migration and that telmisartan inhibited this effect. Hcy increased the expression of AFs AT1R and the phosphorylation levels of PKC and ERK1/2 in the AF and HEK293A cells transfected with the AT1R plasmid, whereas telmisartan inhibited this effect, indicating that Hcy activated AT1R intracellular signaling pathway.Conclusion:Hcy promoted adventitial inflammation, induced AFs migration, and aggravated atherosclerosis by activating AT1R.
The protective role of Professional Self-Concept and Job Embeddedness on Nurses’ Burnout: Structural Equation Modeling
Authors: goliroshan soghra , Nobahar Monir , Raeisdana Nayyereh , ebadinejad zahra , Aziznejadroshan parvin
Published: June 2020

Background and aim: Job embeddedness and professional self-concept are among the important nursing components, the existence of which help decrease occupational burnout among nurses. This study aimed to determine the protective role of Professional Self-concept and Job embeddedness on nurses’burnout. Methods: This descriptive, correlational study had a predictive design and was conducted on nurses working in training and healthcare centers of Babol University of Medical Sciences in 2019. In total, 308 nurses were selected by stratified random sampling. In addition, data were collected using demographic characteristics questionnaire, Professional Self-concept questionnaire, Job embeddedness scale and nurses’ burnout questionnaire. Moreover, data analysis was performed in SPSS version 19 and LISREL version 8.54 using correlational statistics and structural equation modeling. Findings: The results showed, there was a significant, negative relationship between Professional Self-concept and nurses’ burnout (a regression coefficient of -0.77). Meanwhile, an insignificant negative association was found between Job embeddedness and burnout (a regression coefficient of -0.07). The Job embeddedness and self-concept explained 33% of the variance in nurses’ burnout. Conclusion: According to the results of the study, Professional Self-concept had an effective role in nurses’ burnout. In other words, the higher the Professional Self-concept of nurses, the lower their burnout. Therefore, it is suggested that effective interventional strategies be designed by nursing managers through better planning and a supportive workplace be established to improve Professional Self-concept among nurses and decrease their burnout.
Effect of Education Based on the Health Belief Model on Prevention of Sexually Transmitted Diseases in Female Victims of Sexual Assault
Authors: Khakbazan Zohreh , Mehdizadeh Arezu , Azimi Khadijeh , Mirmohammadali Mandana
Published: June 2020

Background: Preventing sexually transmitted diseases is one of the main needs of the victims of sexual assault which their risks could be restricted by providing education to the victims. Therefore, the present study was conducted to evaluate the effect of education based on the Health Belief Model on the prevention of sexually transmitted diseases in female victims of sexual assault.Methods: The present randomized clinical trial was conducted at the forensics center of Babol. Samples were selected randomly and included 70 eligible women and girls who had complained of sexual assault. The intervention group was educated during a half an hour session based on the Health Belief Model with phone follow-up and educational pamphlets; the control group received routine care from the forensic center. Information was gathered at two stages before and after the intervention and then was analyzed.Results: Comparing the intervention and the control groups after the education showed a significant difference in perceived sensitivity and intensity (p = 0.001), perceived benefits (p = 0.04), perceived barriers (p = 0.001), and the performance of complained women and girls after sexual assault in preventing sexually transmitted diseases (p = 0.001).Conclusions: Education based on the Health Belief Model was effective on preventing sexually transmitted diseases. Therefore, it is recommended that this model would be used for the education of sexual assault victims for preventing sexually transmitted diseases.Trial registration: IRCT 2014101413542N3
Hypertension but Not Heart Failure or Coronary Artery Disease is Associated With Mental Disorders
Authors: Namdar Hossein , Jamshidi Fatemeh , Ezzati Davoud , Zakeri raana , Sadat-Ebrahimi Seyyed-Reza
Published: June 2020

Background

Previous studies have emphasized the significant association between depression, anxiety, and stress and hypertension (HTN), heart failure (HF), and coronary artery disease (CAD). However, among included patients with HF or CAD in those studies, there were considerable proportions of patients with concomitant HTN and vice versa leading to some possible bias in final estimations. Therefore, we aimed to exclude those patients with concomitant diseases and reassess the association between these three prevalent cardiovascular diseases with three important psychological disorders.
Methods

In this cross-sectional study, 300 patients were evaluated, including 100 with HTN (without a history or concomitant HF or CAD), 100 with HF (without HTN or CAD), and 100 with CAD (without HTN or HF). Moreover, 100 healthy volunteers were considered as the control group. Depression Anxiety Stress Scale 21 was used to measure the magnitude of depression, anxiety, and stress.
Result

The average scores of 4.6, 9.1, 3.7, and 4.4 for depression, 3.9, 11.1, 4.1, and 3.6 for anxiety and 6.5, 13.6, 5.2, and 5.4 for stress were detected in control, HTN, CAD, and HF groups, respectively. The depression, anxiety, and stress scores of HTN group were significantly higher than the control (p < 0.05), CAD (p < 0.05) and HF (p < 0.05) groups; this is while these scores were not significantly different between other study groups (p > 0.05).
Conclusion

Our study demonstrated a significantly higher magnitude of psychological disorders in patients with HTN. However, their magnitude in patients with HF and CAD without concomitant HTN were similar to those in healthy participants.
Inhibitory Effects of the Spore-forming Bacillus spp. on the Expression Levels of eae, luxS, flu, and ctxM Genes in E. coli Isolates
Authors: baserisalehi majid , Ghane Masood , elahian zahra
Published: June 2020

Background: Escherichia coli infections are one of the major health problems in many countries. The emergence of antibiotic resistance has complicated the treatment of infections caused by this microorganism. Today, researchers are focusing on novel approaches for the treatment of E. coli infections among which is using spore-forming probiotics for their high stability in the harsh gastrointestinal (GIT) environment. Results: This study screened the potential of B. coagulans and B. subtilis to inhibit the expression of flu, eae, luxS, and ctxM genes in 40 E. coli isolated from a total of 300 fecal samples of patients suffering from diarrhea from August 2018 to January 2019. For this purpose, first the presence of these genes was confirmed in the isolates using the PCR method. Then, the standard strains and broiler-derived B. subtilis and B. coagulans were used to screen their ability to tolerate low pH, bile salts, and gastric enzymes. After confirming their ability to survive under the simulant gastric environment, they were cocultured with E. coli isolates (n=4) harboring all the flu, eae, luxS, and ctxM genes. After reaching the logarithmic growth phase, the expression levels of flu, eae, luxS, and ctxM genes were determined using the real-time PCR methods. According to the results, there was a statistically significant relationship between the exposure of E. coli with commercial and broiler-derived spore-forming probiotics and the reduced expression of these genes. Conclusion: The broiler-derived isolates had a greater capacity to decrease the expression of these genes compared to the standard strains, proposing their adoption for dietary supplementations. However, more studies are required to study the effects of these spore-forming bacteria on E. coli infections in vivo and their possible influence on lactose tolerance, nutritional absorption, and reduced cholesterol levels.
Association of a novel missense mutation in MYO15A with nonsyndromic hearing loss: a case report
Authors: Wang Siji , Chen Ziqi , Dai Jiaqiu , Ouyang Xi , Zhu Lin , Xiang Changchao , Yu Fengghui , Kang Houyong
Published: June 2020

Background

Hearing loss is a common disease globally, and more than 50% of the cases are genetic. Autosomal recessive nonsyndromic hearing loss (ARNSHL) is one of the most common types of hereditary hearing loss. Here, a novel MYO15A missense mutation was identified in a Chinese family with ARNSHL, using targeted genetic sequencing and Sanger sequencing.
Case presentation:

A 6-year-old girl with congenital nonsyndromic sensorineural deafness was presented from the First Affiliated hospital of Chongqing Medical University, China. We used targeted region sequencing, Sanger sequencing, functional prediction, and three-dimensional protein structure modeling to identify and verify the genes responsible for deafness in the family.
Conclusions

We found pathogenic compound heterozygous mutations in MYO15A, including a novel missense mutation, c.6353T > C (p.Leu2118Pro). It could provide help not only for genetic counseling but also for further understanding of the functional role of MYO15A mutations.