bluuebunny/crossref_metadata_2025 huggingface dataset:
Regulatory Support of Digital Model of Urban Territory in the Russian Federation
Authors: Mametova T. А. , Karelin D. V.
Published: October 2024

The article studies the digital model of the urban area as a mandatory tool for managing urban processes. The study of the regulatory support of the digital model is of great importance in the light of the rapid development of digital technologies in the urban environment. Purpose: To determine the regulatory support significance in creating the digital model of the urban area and its tools. Geographic information platforms of citywide importance are studied as well as their formation in the legislative field of the Russian Federation. It is assumed that the process of creating the digital model of the urban area, is inevitable in view of the development trend of urban planning in the Russian Federation.Methodology/approach: Based on theoretical analysis and synthesis of various sources of information, the diagram is constructed for information sources on the digital model of the urban area. The regulatory support of the digital model is specified as a basis for the development of geographic information system at all levels of significance. Requirements for regulatory acts of the construction industry for the digital model are formulated. Aspects of the legal field are identified as tools that require reflection in the digital model of the urban area.Value: This research can underlie the creation of regulations or their transformation to contribute to the sustainable and harmonious development of the urban environment.
Identity and Otherness in the Rahab Story. Analysis of the Rahab Speech (Josh 2:9–11)
Authors: Toczyski Andrzej
Published: October 2024

The biblical story of Rahab of Jericho was included in the Book of Joshua to serve a specific purpose in a remote historical context. This article focuses on a possible function of the Rahab story, which might have been employed by the author/redactor as a literary pattern for cross-cultural encounters between different groups, such as the Canaanite clan of Rahab and the Israelites. The Deuteronomistic Law demands the removal of “others” and separation from them, while Rahab, “the outsider,” is saved and protected by the Israelites. This fact may not only prove the benevolence of the Israelites but also be evidence of a recurring literary pattern of constructing national and religious self-identity first through retelling and eventually rewriting stories. Since the Rahab story has been read/heard by ancient audiences and by many readers through the centuries, this pattern may also prove relevant for contemporary readers by providing grounds for intercultural dialogue in the modern world.
Judas’ Proskynesis
Authors: Rzepka Jacek
Published: October 2024

The present article starts from an observation that Mark and Matthew use two different, though cognate words for Judas’ kiss (philein and kataphilein). Kataphilein is omitted from Luke’s passion narrative, while Judas’ kiss as such is absent from John. A closer look is offered at the verb kataphilein in Classical contexts, where it may be synonymous with proskynein (‘to perform a ritual prostration’). It is suggested that what Judas actually performed at Gethsemane was technically proskynesis. Judas’ gesture, perhaps imitated by some of his armed accomplices, was rendered as an unwilling act of reverence to Jesus by some of Judas’ companions in John. It is further argued that the Gethsemane proskynesis was orchestrated in collusion with the temple elites that needed firm evidence of Jesus’ revolutionary activity to obtain the Roman governor’s consent to put Jesus to death (they previously had tried to entrap him in the taxation discourse). As a Roman military unit was present at the arrest of Jesus, Pilate had now several Roman witnesses of the royal style of Jesus, and was forced to act together with the temple elite. This reconstruction speaks for complementarity of the passion narratives in spite of differing highlights of the four evangelists.
Analisis Gangguan Jaringan Transmisi 150 kV menggunakan Disturbance Fault Recorder Alat Pelacak Berbasis Travelling Wave System Pada ULTG Duri
Authors: Arlenny  , Tanjung Abrar , Dharna Alqadri Muhammad Fathur
Published: October 2024

Peranan DFR dalam menganalisa gangguan jaringan transmisi 150 kV ULTG Duri sangat berguna dalam percepatan penormalan sistem transmisi 150 kV, mengetahui jenis dan karakteristik gangguan, serta penentuan lokasi gangguan menggunakan hasil dari data rekaman DFR dengan pembanding alat pelacak berbasis TWS. Berdasarkan pola kejadian gangguan yang terjadi di ULTG Duri pada tahun 2021, diketahui gangguan akibat petir sebanyak 3 kali, dan gangguan akibat pohon atau benda lain sebanyak 1 kali. Dengan diketahuinya karakteristik jenis dari gangguan, hal ini dapat mempercepat evaluasi gangguan dan melakukan penormalan kembali kelistrikan pada ULTG Duri. Perhitungan error jarak lokasi gangguan pada DFR untuk Saluran Transmisi 150 kV Duri – Balai Pungut 1 dan 2 adalah 25,326 %, Duri – Balai Pungut 2 adalah 6,231 %, Duri – Bagan Batu 2 adalah 12,231 %, dan Duri – Bagan Batu 1 dan 2 adalah 1,120 %, sementara perhitungan error lokasi gangguan pada TWS untuk Saluran Transmisi 150 kV Duri – Balai Pungut 1 adalah 7,489 %, untuk Duri – Balai Pungut 2 adalah 2,354 %, Duri Balai Pungut 2 adalah 1,762 %, Duri – Bagan Batu 2 adalah 0,088 %, dan Duri – Bagan Batu 1 dan 2 adalah 0,092 %. TWS sebagai alat bantu pelacak gangguan dapat digunakan sebagai referensi tambahan dalam menentukan lokasi gangguan.
Studi Perbandingan Konsumsi Energi Listrik Pada Motor Kompresor Air Conditioner Jenis Inverter dan Non Inverter
Authors: Masri Jumasri , Zulfahri  , Monice  , Darmansyah
Published: October 2024

Penggunaan energi listrik untuk rumah tinggal sebagian besar digunakan oleh Air Conditioner. AC memerlukan sumber energi listrik yang cukup besar sebagai tenaga penggerak motor kompresor. Untuk itu dibutuhkan AC yang hemat energi listrik, agar biaya yang dikeluarkan menjadi sedikit. Teknologi pada AC inverter dikatakan lebih hemat energi dibandingkan dengan AC non inverter. Oleh karena itu, perlu dilakukan penelitian mengenai “Studi Perbandingan Pemakaian Konsumsi Energi Listrik Pada Motor Kompresor Air Conditioner Jenis Inverter dan Non inverter” Agar dapat membuktikan hal tersebut. Dari hasil pengujian dan analisa yang dilakukan pada ruangan pengujian 3 x 3,5 meter dengan beban pendinginan 6882,089 Btu/h, diperoleh bahwa Konsumsi energi listrik pada AC Daikin inverter FTKQ20SVM4 selama 1 bulan pada suhu seting 25°C adalah 28,82 kWh dengan biaya Rp.41.636. Sedangkan konsumsi energi listrik pada AC Sharp non inverter AH-A7SAY selama 1 bulan pada suhu seting 25°C adalah 78,1 kWh dengan biaya Rp.112.831. Dengan demikian dapat disimpulkan bahwa AC inverter lebih hemat energi dibandingkan AC non inverter
Native gold from alluvial deposits of the Kyvvozhsky district and its probable primary sources (Volsko-Vymskoe rise, Middle Timan)
Authors: Parkhacheva К. G. , Glukhov Yu. V. , Sokerin М. Yu. , Kuznetsov S. К. , Shaybekov R. I.
Published: October 2024

Based on the study of typomorphic features of gold from alluvial deposits of the Kyvvozh region of Middle Timan, including industrial placers, the most probable genetic types of primary sources were determined. The size of gold particles varies widely, reaching the size of small nuggets; along with rounded ones, there are weakly rounded and unrounded particles. Many of them have undergone repeated deformations in the form of envelope-shaped bends, dents and tears. Most gold coins have high-fineness rims. Gold always contains Ag, sometimes Cu, Pd and Cu. Gold particles with a block structure with high-silver vein zones are often found. In intergrowths with gold and in the form of inclusions are noted in it pyrite, galena, and occasionally minerals of the cobaltine-gersdorfite series, ankerite, galenobismutite, native bismuth, aurostibite, and also sudovikovite (PtSe2), which was first identified in the region. Three types of gold have been identified: 1 – homogeneous silver-containing, 2 – block with highly silvery vein-like zones, 3 – rare silver-containing with impurities of Cu, Pd. The morphology, composition and structure of placer gold indicate its entry into placers from various sources, including nearby sources. Of greatest interest are the zones of development in Riphean rocks of hydrothermal veinlet-disseminated sulfide mineralization, oriented in the northwest direction, partially exposed during the development of placers. Gold with Cu and Pd impurities is most likely associated with derivatives of mafic magmatism. The Volsko-Vymskoe, as well as the Tsilemskoe and Chetlasskoe uplifts of Middle Timan can be considered promising in terms of primary gold content and deserve further study and prospecting.
Soviet military assistance to Turkey in 1920–1922
Authors: Shubin Aleksandr V.
Published: October 2024

In the article, the author examines the supply of arms from the Soviet republics to Turkey between 1920 and 1922. He primarily draws on documents from the Russian State Military Archive (RGVA) to elucidate the scope and dynamics of the arms supplies, which were instrumental in enabling Turkey to defend its independence and territorial integrity in the challenging struggle with the Entente states. The available evidence indicates that, with the exception of a brief period in late 1920, Russia consistently supplied arms to the best of its capabilities, even during the cooling of relations in early March 1921. While Soviet-made weapons played a pivotal role in the Turkish Army’s operations against Armenia, they were particularly instrumental in its victory at Sakarya. As the Greco-Turkish War drew to a close, the Soviet contribution to the conflict diminished as French weapons began to arrive. However, Soviet gold also became a means of financing this military aid. By comparing the data from the RGVA documents with the estimates previously published in Russia that referenced Turkish sources, the author concludes that the materials preserved in the Russian archive provide a more accurate assessment of the scale, quality, and dynamics of the supplies provided. The quality of weapons provided was sufficiently high to enable effective resistance to the Greek invasion of Anatolia.
Promising Directions for Regulating Signaling Pathways Involved in the Type 2 Diabetes Mellitus Development
Authors: Borozdina N. A. , Popkova D. V. , Dyachenko I. A.
Published: October 2024

Many studies confirm that substances of natural origin have a pronounced affinity for type 2 diabetes mellitus (T2DM) therapeutic targets. At the moment, there is growing interest in bioactive peptides, phytochemicals, and drugs from other natural sources as highly effective, safe and promising antidiabetic agents. Natural sources are a promising resource for regulating several pathological pathways in T2DM. The review describes ways to mitigate insulin resistance and tissue sensitivity to glucose through PTP1β (protein tyrosine phosphatase 1β), GLP-1R (glucagon-like peptide receptor), DPP-4 (dipeptidyl peptidase-4), AMPK (adenosine monophosphate activated protein kinase), MAPK (mitogen-activated protein kinase). Regulation of obesity and oxidative stress development through CCN3 (nephroblastoma overexpressed gene), PPAR-γ (peroxisome proliferator-activated receptor γ), Nrf2 (nuclear factor erythroid-related factor 2), FFAR (free fatty acid receptors), 11β-HSD1 (11β-hydroxysteroid dehydrogenase). Regulation of hyperglycemia through alpha-amylase inhibitors, regulation of glucose metabolism through GFAT (glutamine fructose-6-phosphate aminotransferase), FOXO1 (forkhead box protein O1), GLUT4 (glucose transporter type 4), PGC-1α (receptor gamma coactivator 1α activating peroxisome proliferator). The review examines the use of natural sources, from which low-molecular-weight and peptide compounds are used as T2DM targets modulators.
Ultrafast Photochemical Reaction of Exiguobacterium sibiricum Rhodopsin (ESR) at Alkaline pH
Authors: Smitienko O. A. , Feldman T. B. , Petrovskaya L. E. , Kryukova E. A. , Shelaev I. V. , Gostev F. E. , Cherepanov D. A. , Kolchugina I. B. , Dolgikh D. A. , Nadtochenko V. A. , Kirpichnikov M. P. , Ostrovsky M. A.
Published: October 2024

Rhodopsin from the eubacterium Exiguobacterium sibiricum (ESR) performs the function of light-dependent proton transport. The operation of ESR is based on the ultrafast photochemical reaction of isomerization of the retinal chromophore, which triggers dark processes closed in the photocycle. Many parameters of the photocycle are determined by the degree of protonation of Asp85 – the primary counterion of the chromophore group and the proton acceptor. ESR in detergent micelles pumps protons most efficiently at pH 9, when Asp85 is almost completely deprotonated. In this work, the photochemical reaction of ESR at pH 9.5 was studied by femtosecond laser absorption spectroscopy. It was shown that photoisomerization of the chromophore group occurs in 0.51 ps, and the contribution of the reactive excited state is about 80%. A comparison with the data we obtained at pH 7.4 showed that at pH 9.5 the reaction proceeds much faster and more efficiently. The data obtained confirm the important role of the chromophore group counterion in the photoactivated processes of rhodopsins.
The Influence of Peptide Linkers on Functional Properties of Hybrid Structures with the Selective pH-Dependent Binding to Cancer Cells
Authors: Frolova A. Yu. , Pakhomov A. A. , Deyev S. M. , Martynov V. I.
Published: October 2024

Most of the modern cancer therapies are non-specific and have adverse side effects on the body. Nowadays, targeted cancer therapies are being developed, in particular using targeting peptides that selectively bind to cancer cells. The aim of the present work is to explore the prospects of using a peptide pHLIP that binds to cancer cells at decreased pH values, as a part of recombinant protein-peptide construct for cancer diagnosis and targeted therapy. Hybrid structures based on the fluorescent protein EGFP and a linker sequence connecting fluorescent protein to two different pHLIP variants were obtained. The effect of different linkers on the pH-dependent binding of the constructs to cells, as well as on the efficiency of EGFP chromophore synthesis within the hybrid construct was investigated.
On the relationship of mental and biological in the problem of modeling consciousness
Authors: Zelenkova T. V.
Published: October 2024

The problem of mental modelling and creation of thinking devices is one of the most significant and at the same time, the least studied in modern science. The main difficulties in solving it are associated with insufficient elaboration of the relationship between the mental and the biological, primarily from the conceptual apparatus and a unified methodological base. The article discusses the issues of the definition of alive, the emergence of the psyche, the concept of pan-interiorism, existing models of consciousness and their criticism from the position of non-disjunctive logic and proposes a new semiotic model based on a cultural substrate. The work is an attempt at an interdisciplinary synthesis of views on the above problems of the largest scientists of the XX and XXI centuries: V.I. Vernadsky, S.L. Rubinshtein, A.V. Brushlinsky, M.M. Bakhtin, Yu.M. Lotman and others. The possibility of building artificial intelligence based on cultural substrate is substantiated, as it is proposed to use semiotic systems, whose properties in many respects resemble the properties of a living organism: they possess the mechanism of autopoiesis, follow the Redi principle, are organized in the form of cholarchy, and exist only in a communicative environment.
Education as a functional resource for the development of the State: an analysis of the socio-economic views of Russians
Authors: Kitova D. A. , Zhuravlev A. L.
Published: October 2024

The study was devoted to identification of the population’s everyday ideas about the functional capabilities of education that can have an impact on the development of the state. The methodological approach and research methods are based on the fact that the perception of macroeconomic processes determined by the development of education will be reflected in the everyday ideas of the population, which can be studied through structural and content analysis of the texts of messages on social networks. The work used methods of grounded theory, neural network analysis, analysis of the frequency of occurrence and emotional background of words, content and expert analysis. It is shown that, according to users of social networks, the leading functions of education are associated with its ability to influence the social, economic and political development of society and the state, including as a geopolitical subject. Users associate education with various levels of development of socio-economic processes — from personal to national. The functional essence of education as a resource for the macroeconomic development of the state dominates over other aspects (micro- and meso-levels) of ideas and demonstrates a clearly defined hierarchical relationship of priorities: national, historical, systemic, global, institutional, regional and meso-economic. As part of the discussion of educational processes, differences arise between supporters of state-oriented and socially-centered ways of developing society. The historical conditionality of Russian education among users correlates with the peculiarities of its development in the USSR, and there is no connection to earlier periods of history. Education from a functional perspective is assessed by users as a benefit for individuals and society, the achievement of which requires significant time and socio-economic costs on the part of all its participants (the state, teachers and students). Insufficient satisfaction with higher education is manifested by the majority of users and is due to an assessment of its current state. The identified results require further specification, for example, the study of algorithms proposed to overcome the current situation.
Professionally important personal prerequisites for entrepreneurship
Authors: Rubin Yu. B. , Shadrikov V. D.
Published: October 2024

The purpose of the article is to identify, systematize and structure personal prerequisites of people that are professionally important for successful entrepreneurship, in the context of interdisciplinary research into the phenomenon of entrepreneurship and its functional specifics. The understanding of entrepreneurship as a special type of professional activity, carried out in accordance with the request for it from society and its segments, extends to the analysis of the personal prerequisites for the professional development of modern entrepreneurs. Based on the psychological theory of activity, modern theories of abilities and on functional ideas about entrepreneurship as a type of professional activity, a professional-centric approach to assessing personal prerequisites that are important for successful entrepreneurship on a professional basis, as well as for the entrepreneurial professionalization of actors, is formulated. Special objects of consideration are clusters of professionally important prerequisites — people’s entrepreneurship ability, their personal competitiveness, ownership propensities. The illegality of synonymizing entrepreneurship as a type of activity and the entrepreneurship ability as a prerequisite for the success of this activity is argued. Entrepreneurship contains a readiness to make decisions, implement a program of action, reflect on the results of activity in an environment of comparative uncertainty of the market realities of the business environment, as well as to take on professional risks. The ownership propensities is interpreted as prerequisites that are professionally important for de facto entrepreneurs as business owners. It is shown that the personal competitiveness of the actors of this type of professional activity is of professional importance for successful entrepreneurship throughout the centuries-old history of reproducing the competitive nature of the entrepreneurship environment.
Seventh international scientific and practical conference “Social and psychological adaptation of migrants in the modern world”
Authors: Konstantinov V. V. , Khashenko N. N.
Published: October 2024

22–23 марта 2024 г. состоялась 7-я Международная научно-практическая конференция “Социально-психологическая адаптация мигрантов в современном мире”. Организаторами выступили Пензенский государственный университет и Костанайский региональный университет им. Ахмета Байтурсынова (Казахстан). Работа конференции была организована в гибридном формате — очно и с помощью видеоконференцсвязи Контур.Толк. Участниками обсуждены вопросы, связанные с проблемным полем социально-психологической адаптации мигрантов и беженцев в России и в других странах. Отдельной темой для анализа и дискуссии стала проблема организации психолого-педагогической помощи мигрантам и беженцам. По итогам работы конференции был опубликован сборник материалов, раскрывающий широкий спектр исследований современных психологов в области социально-психологической адаптации мигрантов.
Analysis of Molecular Mechanisms of Chronic Irradiation Effects on Electrical Signals in Wheat Plants
Authors: Pirogova P. A. , Zdobnova T. A. , Ivanova A. V. , Grinberg M. A. , Vodeneev V. A.
Published: October 2024

The effect of ionizing radiation (IR) on plants is mainly realized by altering the status of signaling systems and modifying stress signals. Variation potential (VP) is one of the types of electrical signals in plants. IR contributes to an increase in the amplitude of the VP, but the mechanisms of such influence are practically unknown. A possible way to implement changes arising from the action of IR is the regulation of gene expression. In the present work, the changes in the gene expression of participants in the generation and propagation of VP in irradiated plants are investigated. The experiments were performed on 14–15-day-old soft wheat plants (Triticum aestivum L.) grown under chronic irradiation (source 90Sr-90Y) with a dose rate of 31.3 μGy/h. The maximum accumulated dose was about 11.3 mGy. The irradiated plants showed no changes in the expression of calcium (TPC1), anionic (ALMT1 and CLC1), potassium (AKT1) channels, H+-ATPase (HA1), and NADPH oxidase (RBOHs) genes. A decrease in the expression of the SKOR potassium channel gene was revealed. The potassium channel blocker, tetraethylammonium chloride, caused an increase in response amplitude in control plants comparable to the increase in amplitude in the irradiated group. The obtained results indicate that one of the ways IR influences the electrical signals of plants is to inhibit the expression of the potassium channel.
Rottenpflege unter Klimawandel: Möglichkeit einer Durchforstung
Authors: Banzer Theresa , Frehner Monika , Bottero Alessandra
Published: October 2024

Als Folge des Klimawandels profitieren temperaturlimitierte Gebirgswälder von höheren Bodentemperaturen, was das Wachstum der Fichte (Picea abies) begünstigt. In der subalpinen Höhenstufe führte dies zu einer verstärkten Ausdehnung der Fichtenkronen und damit zu verschmälerten Gassen zwischen Rotten. Weil die Kronen der Randbäume stärker wachsen als erwartet, reicht der Gassenabstand im Untersuchungsgebiet vermutlich nicht aus, um die grünen Kronenränder der Rotten längerfristig zu erhalten. Die vorliegende Arbeit untersuchte zwölf Rotten in einem Schutzwald in der Surselva. Dabei wurden sechs Rotten nach klassischem Rottenmanagement bewirtschaftet, während die anderen sechs Rotten im Jahr 2012 durchforstet wurden. Ziel der Arbeit war es, mittels dendrochronologischer Analysen den Einfluss unterschiedlicher Bewirtschaftungsarten (durchforstet / nicht durchforstet) sowie Positionen (Rand/Zentrum) auf den Basalflächenzuwachs der Bäume zu quantifizieren und deren Wachstumsreaktion auf extreme Trockenheit darzustellen. Die durchforsteten Rotten sind durch einen stärkeren Basalflächenzuwachs sowie eine grössere Wachstumsresistenz gegen Trockenheit, insbesondere bei den Randbäumen charakterisiert. Der Waldbestand der untersuchten Fläche befindet sich derzeit in einem stabilen Zustand. Doch unter Einfluss des Klimawandels wird künftig nicht nur die jährliche Durchschnittstemperatur weiter steigen, sondern auch die Gefährdung durch biotische und abiotische Störungen zunehmen. Insbesondere auf sehr trockenheitslimitierten Standorten könnte eine Durchforstung im jungen Bestandalter eine Möglichkeit sein, die Anfälligkeit der Fichte gegenüber Trockenheit zu verringern.
Untersuchung der Produktivität von Pflanzungen bei zehn Schweizer Forstbetrieben
Authors: Werder Marc , Schweier Janine
Published: October 2024

In den Schweizer Wäldern werden Störungen zunehmen. Bei unzureichender Natur- oder Vorverjüngung kann eine aktive Pflanzung deshalb zielführend sein. Der Fokus richtet sich dabei auf die Einbringung von Artenvielfalt und klimastabile Baumarten, um die Resilienz des Waldes zu stärken. Das WSL-Tool JuWaPfl (Jungwaldpflege) stellt für die Forstpraxis Modelle zur Abschätzung von Produktivität und Kosten der ersten Produktionsstufe bereit. Vor dem Hintergrund der aktuellen Herausforderungen gehen wir davon aus, dass der Bedarf nach Leistungskennziffern in den nächsten Jahren weiter anhalten oder gar steigen wird. Deshalb haben wir die Modelle «Pflanzung» und «Wildschutz-Massnahmen» überarbeitet und die Leistung von Pflanzungen mit unterschiedlichen Werkzeugen (u.a. Anbringung verschiedener Wildschutzmassnahmen) untersucht. Neben den reinen Leistungskennzahlen, die in die Aktualisierung der Modelle geflossen sind, teilen wir in diesem Beitrag unsere Erfahrungen und Erkenntnisse über Pflanzverfahren, eingesetzte Werkzeuge, verwendete Baumarten, Pflanzgut und Pflanzzeitpunkt.
ОПТИМІЗАЦІЯ СТРАТЕГІЇ STР-МАРКЕТИНГУ АГРАРНИХ КОМПАНІЙ РЕГІОНУ НА ОСНОВІ ШТУЧНОГО ІНТЕЛЕКТУ ТА ПРИНЦИПІВ SMART-СПЕЦІАЛІЗАЦІЇ
Authors: КОЛОМИЦЕВА Олена , ШЕВЧЕНКО Наталія , СЕРГІЄНКО Олександр
Published: October 2024

У статті розглянуто особливості оптимізації стратегії STP-маркетингу аграрних підприємств на основі технологій штучного інтелекту та принципів smart-спеціалізації. Визначено роль сегментації, таргетингу й позиціонування для підвищення ефективності взаємодії з різними групами споживачів. Обґрунтовано важливість впровадження ШІ для підвищення точності ринкових прогнозів і поліпшення комунікаційних стратегій, що забезпечує інноваційний розвиток аграрних компаній. Визначено та структуровано завдання, що вирішуються штучним інтелектом у забезпеченні позиціонування  аграрних компаній на ринку . Наведено типи інструментів штучного інтелекту, що відповідають завданням STP-маркетингу, представлено їх опис і проаналізовано результати застосування. Розглянуто переваги адаптації стратегії STP-маркетингу у відповідності до концепції smart-спеціалізації, що дозволяє аграрним підприємствам використовувати унікальний потенціал регіональних ресурсів, сприяючи сталому економічному й соціальному розвитку та інтеграції екологічних стандартів.
Evaluación cualitativa de servicios ecosistémicos, estudio de caso, Reserva Natural Palma de Cera
Authors: Parrado-Guatavita Natalia Andrea , Serrato-Suárez Oscar Eduardo , Matallana-Laguna Wendy Alexandra
Published: October 2024

Los Servicios Ecosistémicos (SSEE) se pueden entender como el vínculo entre el sistema social y ecológico, donde, el primero, se considera como aquel que goza de estos servicios y, el segundo, referido a la capacidad de los ecosistemas de proveer estos beneficios. Esta investigación, a través de una metodología cualitativa, evalúa los SSEE, clasificados en tres categorías: regulación, abastecimiento y culturales, derivados de la Reserva Natural Palma de Cera, ubicada en La Vega, Cundinamarca, usufructuados por grupos de interés, identificados y caracterizados, quienes mantienen una relación con el área de estudio. Para ello, inicialmente, se identificó, por medio de herramientas GIS, el ecosistema que corresponde a agroecosistema campesino mixto; las coberturas presentes, como bosque fragmentado con pastos y cultivos, Bosque fragmentado con vegetación secundaria y plantación de coníferas y, posteriormente, para mayor detalle, se catalogaron los usos de suelo para el 2023, entre los cuales, se encuentran bosque en recuperación y sistema agroforestal (SAF), que representan la mayor extensión. Es así, como su evaluación, empleando el Análisis Multicriterio, deja entrever que el conocimiento y la percepción de la comunidad define el grado de importancia de cada servicio, tanto así, que los actores locales atribuyeron mayor grado de importancia a los beneficios tangibles y de uso directo, es decir, SSEE de abastecimiento; por otro lado, profesionales ambientales y ecoturistas priorizan los servicios de regulación por encima de los demás.
Publishing and using parliamentary Linked Data on the Semantic Web: ParliamentSampo system for Parliament of Finland
Authors: Hyvönen Eero , Sinikallio Laura , Leskinen Petri , Drobac Senka , Leal Rafael , La Mela Matti , Tuominen Jouni , Poikkimäki Henna , Rantala Heikki
Published: October 2024

This paper presents a new infrastructure and semantic portal called ParliamentSampo for studying parliamentary speeches, culture, language, and activities in Finland. For the first time, the entire time series of some million plenary speeches of the Parliament of Finland (PoF) since 1907 have been converted from text into knowledge graphs and data services in unified formats, including CSV, Parla-CLARIN, ParlaMint, and RDF Linked Open Data (LOD). The speech data have been interlinked with a semi-automatically created ontology and a knowledge graph about the activities of over 2800 Members of Parliament (MP) and other speakers in the plenary sessions of the PoF. The data was enriched by data linking to external data sources and by reasoning into a broader LOD service. Knowledge extraction techniques based on Natural Language Processing (NLP) were used for automatic semantic annotations and topical classification of the speeches. The data and data services have been used in Digital Humanities (DH) research projects and for application development, especially for developing the in-use semantic portal ParliamentSampo. The infrastructure and the portal were published on February 14th 2023 on the Web using the open CC BY 4.0 license, and quickly gathered thousands of users, including citizens, media, politicians, and researchers of politics. ParliamentSampo is a new member in the “Sampo” series of over 20 interlinked LOD services and semantic portals in Finland, based on a national Semantic Web infrastructure. Although the paper uses Finnish parliamentary data as a case study, the approach, methods, and tools presented can be adapted also to other parliamentary datasets in other countries.
Comparative outcomes of treatment of polycystic ovarian syndrome using optimized surgical techniques
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Dobrokhotova Yu.E. , Grishin I.I. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Il'ina I.Yu. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Ogede O.R. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: October 2024

Aim: to optimize the algorithm for surgical management of polycystic ovary syndrome (PCOS) in women with impaired reproductive function and infertility. Patients and Methods: the study included 60 women of reproductive age between 18 and 35 years with PCOS and infertility. Group 1 consisted of 30 women (mean age 26.9±4.8 years) who underwent energy-free laparoscopic ovarian drilling (during the procedure, the tunica albuginea was destroyed with endoscopic scissors). Group 2 consisted of 30 women who underwent CO2 laser drilling. There were no significant differences between the groups in menstrual function, number of pregnancies, gynecological and extragenital diseases. The treatment effect on ovulation, menstrual cycle, fertility, pregnancy, and hormone levels was evaluated 1 month and 3 months after surgery. Results: аfter surgery, a significant decrease in the number of complaints, including menstrual disturbances, was reported in all women in groups 1 and 2. A significant decrease in the levels of luteinizing hormone (LH), anti-Müllerian hormone, and free testosterone, as well as in the ratio of LH to follicle-stimulating hormone (FSH), was observed in both groups. The groups differed significantly (p <0.05) in ovulation and pregnancy rates. Ovulation occurred in 28 (93.33%) women in group 1 and 21 (70%) women in group 2. Pregnancy occurred in 26 (86.66%) and 18 (60%) women, respectively. There were no postoperative complications in either group. Conclusions: energy-free laparoscopic ovarian drilling for PCOS resulted in a higher rate of spontaneous pregnancy compared to laser drilling. KEYWORDS: infertility, laparoscopic ovarian drilling, polycystic ovary syndrome, energy-free laparoscopic ovarian drilling, laser drilling. FOR CITATION: Dobrokhotova Yu.E., Grishin I.I., Il'ina I.Yu., Ogede O.R. Comparative outcomes of treatment of polycystic ovarian syndrome using optimized surgical techniques. Russian Journal of Woman and Child Health. 2024;7(3):222–226 (in Russ.). DOI: 10.32364/2618-8430- 2024-7-3-4.
Yerba Mate as functional food in the prevention of civilization diseases
Authors: Rząsa-Duran Elżbieta , Kryczyk-Poprawa Agata , Kała Katarzyna , Muszyńska Bożena
Published: October 2024

Przedmiot badań. Związki fenolowe występują powszechnie w jadalnych surowcach i produktach roślinnych, a więc stanowią istotny element diety, a ich właściwości antyoksydacyjne i przeciwzapalne są ważne z punktu widzenia profilaktyki chorób cywilizacyjnych. Cennym źródłem związków fenolowych, jak również alkaloidów purynowych, w tym kofeiny, w codziennej diecie są napoje: herbata, kawa oraz yerba mate.
Cel badań. Celem pracy była charakterystyka gatunku Ilex paraguariensis, którego liście i gałązki są powszechnie wykorzystywane do otrzymywania napoju yerba mate. Napój ten ze względu na unikatową zawartość związków fenolowych ma ogromny potencjał, aby zostać zaliczony do żywności funkcjonalnej. W pracy zostały opisane związki odpowiedzialne za aktywność biologiczną surowca oraz ich przyswajalność, a tym samym ich potencjalne prozdrowotne znaczenie w organizmie człowieka.
Materiały i metody. Dokonano analizy literatury naukowej w językach polskim i angielskim, korzystając z baz danych, takich jak PubMed i Scopus. Dodatkowo korzystano z wytycznych i dyrektyw Europejskiej Agencji Leków (EMA), Komisji Europejskiej, Agencji ds. Żywności i Leków (FDA) oraz monografii z „Farmakopei Polskiej”.
Wyniki. Związki bioaktywne oznaczone w liściach Ilex paraguariensis posiadają przede wszystkim działanie przeciwzapalne, przeciwdrobnoustrojowe, przeciwutleniające, o potencjalnym zastosowaniu w zaburzeniach metabolicznych, w tym kontroli masy ciała i cukrzycy. Związki polifenolowe obecne w Ilex paraguariensis ulegają w przewodzie pokarmowym licznym modyfikacjom pod wpływem mikrobioty jelitowej, a proces ten ma zasadnicze znaczenie dla ich biodostepności. Potrzebne są jednak dalsze badania nad ustaleniem struktur powstających metabolitów kwasów fenolowych oraz ich roli w organizmie człowieka.
Wnioski. Surowiec pozyskiwany z Ilex paraguariensis może odegrać znaczącą rolę w zbilansowanej diecie człowieka. Napój yerba mate jest naturalnym źródłem substancji z grupy alkaloidów purynowych, dlatego wykazuje działanie psychostymulujące oraz poprawia koncentrację, będąc alternatywą np. dla napojów zawierających kofeinę.
Cost-effects of non-adherence to treatment recommendations - scope review
Authors: Świątoniowska-Lonc Natalia , Szalonka Adrianna , Szalonka Katarzyna
Published: October 2024

Przedmiot badań
Przeciwdziałanie nieprzestrzeganiu zaleceń terapeutycznych z punktu widzenia ekonomicznego powinno być kluczową strategią w obniżaniu kosztów leczenia i osiągnięciu korzyści zdrowotnych zarówno dla jednostek, jak i całych populacji.

Cel badań
Niniejszy przegląd literatury miał na celu określenie najczęstszych ekonomicznych konsekwencji nieprzestrzegania zaleceń terapeutycznych w populacji pacjentów chorych przewlekle oraz wskazanie możliwych sposobów na zmniejszenie poziomu nieprzestrzegania tych zaleceń.

Materiały i metody
Przegląd ten został opracowany na podstawie prac zindeksowanych w bazach danych, takich jak PubMed, MEDLINE, CINAHL, Web of Science oraz Scopus. Kryteria włączenia obejmowały pełnotekstowe artykuły dostępne w języku angielskim, opublikowane w latach 2013-2023, które poruszały temat ekonomicznych skutków nieprzestrzegania zaleceń terapeutycznych w chorobach przewlekłych.

Wyniki
Analizowane badania wykazały, że przestrzeganie zaleceń terapeutycznych jest zarówno mniej kosztowne, jak i bardziej skuteczne. Główne czynniki nieprzestrzegania zaleceń terapeutycznych to wysokie koszty leków oraz niski status ekonomiczny pacjentów. Zgodnie z dostępnymi badaniami, nieprzestrzeganie zaleceń terapeutycznych przez pacjentów przewlekle chorych wiąże się z wysokimi kosztami leczenia, hospitalizacji oraz opieki długoterminowej.

Wnioski
Wysokie koszty związane z nieprzestrzeganiem zaleceń terapeutycznych obejmują również wydatki związane z częstszymi wizytami u specjalistów, dodatkowymi badaniami diagnostycznymi oraz zwiększoną potrzebą interwencji medycznych. Ponadto, zły stan zdrowia wynikający z nieprzestrzegania zaleceń może prowadzić do obniżenia produktywności pacjentów, co z kolei wpływa na ich zdolność do pracy i generowania dochodów. To wszystko przyczynia się do dodatkowych kosztów społecznych, takich jak obciążenie opiekunów oraz spadek jakości życia pacjentów i ich rodzin. Ważnym aspektem jest współpraca pracowników ochrony zdrowia z pacjentami w celu opracowania spersonalizowanych planów leczenia, które są realistyczne, dostępne i dostosowane do potrzeb oraz preferencji pacjentów. Skuteczne przeciwdziałanie nieprzestrzeganiu zaleceń terapeutycznych z perspektywy ekonomicznej może prowadzić do znacznych oszczędności oraz poprawy jakości życia pacjentów, co jest istotnym celem zarówno dla systemów opieki zdrowotnej, jak i dla całych społeczeństw.
Design, Synthesis, and In-Silico Analysis of Thiazole-Embedded Schiff Base Derivatives for Breast Cancer Therapeutic Potential
Authors: Khanam Maher Afroj , Sutradhar Ranajit Kumar , Nath Ashutosh , Chowdhury Mamiya , Dutta Keya Rani , Belowar Sanjay
Published: October 2024

Thiazole-derived Schiff base compounds possess significant pharmacological properties, influencing various enzymes in metabolic pathways and exhibiting antibacterial, antifungal, anti-inflammatory, antioxidant, and antiproliferative activities. This study delves into the synthesis, characterization, and in-silico analysis of ten thiazole-embedded Schiff base derivatives (TZ1-10), benchmarking them against five Food and Drug Administration (FDA)-approved breast cancer drugs. Molecular docking against multiple therapeutic targets related to fatty acid synthase and cell proliferation (PDB IDs: 4FX3, 4OAR, 3NUP, and 3ERT) alongside ADME and Lipinski rule assessments were conducted. Compounds TZ6 and TZ8 emerged as promising candidates with docking scores of -8.0 kcal/mol and -8.2 kcal/mol respectively against the 4FX3 protein. These findings contribute to a deeper understanding of thiazole-embedded Schiff base derivatives, showcasing their potential for future medicinal and scientific applications.
Entangled Simultaneity: Testing Lorentz and Light-Speed Invariance with Quantum and Classical Entanglement
Authors: Spavieri Gianfranco , Mendoza Sánchez Juan Carlos , Carrasquero Ramón , Flores G. Andres J. , Nieves Kevin J Durán , Contreras Antonio
Published: October 2024

In a rod of length AB \(= L\), rotating uniformly, any two spatially separated points along the rod are connected in a way that shows analogies with the quantum entanglement of the spin of particles. This ”classical entanglement” reflects the simultaneity preset in the system, which can be used for syncing two distant clocks, one at A and the other at B. Since it differs from Einstein synchronization, this procedure can be adopted for testing the one-way light speed and Lorentz invariance. Applications to optical Sagnac effects confirm that a consistent interpretation requires the adoption of absolute versus relative simultaneity.
Localized Injection of Semaglutide, a GLP-1 Agonist, for Hyperinsulinemia-Induced Lymphatic Dysfunction A Novel Therapeutic Strategy for Lymphedema Treatment
Authors: Akl Maher M. , Ahmed Amr
Published: October 2024

Lymphedema, traditionally considered a secondary complication of lymphatic damage, may have a deeper, metabolic etiology tied to chronic hyperinsulinemia and insulin resistance. This emerging hypothesis posits that prolonged hyperinsulinemia drives lymphatic endothelial cell (LEC) dysfunction, initiating inflammation, oxidative stress, and structural damage that culminates in impaired lymphatic drainage. Insulin resistance disrupts the PI3K/Akt signaling pathway, which is vital for lymphangiogenesis and endothelial health, further exacerbating lymphatic vessel integrity. Recent clinical evidence underscores the therapeutic potential of GLP-1 receptor agonists (GLP-1RAs), known for their insulin-sensitizing and anti-inflammatory properties. Notably, cases of breast cancer-related lymphedema have shown marked improvements following GLP-1RA treatment, with significant reductions in limb volume and restoration of lymphatic function. These observations suggest a dual mechanism by which GLP-1RAs address both the metabolic and vascular components of lymphedema, positioning them as a promising therapeutic avenue for lymphedema driven by insulin resistance. This review delves into the molecular pathophysiology of lymphedema in the context of metabolic dysfunction and explores the role of GLP-1RAs as an innovative treatment strategy.
Organizational Agility and Performance: A Time-Series Analysis of Crisis Response
Authors: Lavdari Frans , Lavdari Xhulio
Published: October 2024

The paper discusses how this affects the financial resilience across industries, using Amazon, Ford, Toyota, and Pfizer from 2008 to 2023, with further forecasts up to 2028. It utilizes the ARIMA model in computing the extent to which agility in operational, financial, and strategic dimensions leads to recoveries and performance during economic turmoil. In this regard, the adaptability of Amazon and Toyota further increased its growth, but Ford and Pfizer demonstrated really constrained flexibility due to the limitations of their industries. The approach of Toyota to lean manufacturing proves that structured agility can also work for traditional industries. Besides, Pfizer's short-term gains from rapid innovation underlined the relevance of Pfizer's long-term strategic agility. Based on the case study, several contributions are created to the dynamic capability theory: agility works best within an industry context and within the discipline in finance. This conference is insightful for leaders seeking to bring agility into various industries' diverse operational requirements, showcasing agility as both the great factor of competitive advantage and stability.
Cybersecurity issues in addressing the global challenges of the un in the fight against terrorism
Authors:   Eurasian Communications Centre, Sadykova R.E.
Published: October 2024

Today, cybersecurity threats are one of the main problems faced by all countries. Cyberspace plays an important role in our modern life, uniting people and communities around the world, providing them with the opportunity for socialization and self-organization. This article highlights the main types of cyberattacks and threats, as well as suggests methods to prevent them. Various types of cybercrimes are considered, as well as the necessary actions to combat cyberterrorism. Cybercriminals actively use various methods and techniques to carry out cyber attacks, including unauthorized access to systems, theft of personal information, financial fraud and the distribution of malicious software. Cyberterrorism is also a danger, since cyber attacks can be used to create chaos and disrupt the functioning of critical infrastructures, such as government institutions, healthcare systems, energy, and so on. To ensure cybersecurity, cooperation is necessary both at the state and at the international level. Cooperation at the state level includes joint initiatives to exchange information about threats, joint trainings and exercises to improve the skills of cybersecurity specialists, as well as the development of common standards and policies in the field of cybersecurity. At the international level, it is important to establish a dialogue between various countries and international organizations, such as the UN, the European Union, NATO and others. This will allow us to coordinate strategies, coordinate measures to prevent and respond to cyber attacks.
Factors related to futile care and its consequences in intensive care units: A narrative review
Authors:   Student Research Committee, Nasibeh School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran, Moalemian Gorji Razieh , Araghian Mojarrad Fereshteh ,   Traditional and Complementary Medicine Research Center, Addiction Research Institute, Mazandaran University of Medical Sciences, Sari, Iran, Kamali Mahsa ,   Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran, Ghaffari Salman ,   Department of Orthopedics, Orthopedic Research Center, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran, Jafari Hedayat ,   Traditional and Complementary Medicine Research Center, Addiction Research Institute, Mazandaran University of Medical Sciences, Sari, Iran
Published: October 2024

Futile care includes not only end-of-life care but any care that cannot cause the patient to survive and be discharged from the hospital or preserve the quality of life is also called futile care. Providing futile care comes with many challenges. Therefore, this review was conducted to assess futile care and its related factors in intensive care units. This study was conducted as a narrative review. The factors related to the perception of futile care included individual and organizational factors. The consequences of futile care on nurses include increasing moral distress, decreasing job satisfaction, high levels of depersonalization of negative caring behavior, and weakening healthcare professionals' morale. According to the findings, nursing officials should reduce unnecessary care in special departments by increasing nurses' knowledge and supporting strategies, and designing effective care programs.
The Influence of the Number of Banks, Distribution of Funds, and Sources of Funds on the Performance of Commercial Banks in Indonesia
Authors: Aziz Khalid Fauzi , Handoyo Ugroseno Damara Prasadhana , Nur Indra Muksin
Published: October 2024

This research aims to determine the impact of the number of banks, distribution of funds, and sources of funds on the general performance of banks in Indonesia. The location of this research is Indonesia. The object of this research is to collect data on the number of banks, distribution of funds, sources of funds, and performance of commercial banks in Indonesia, taken from the Central Statistics Agency website during 2018–2022. The data analysis method used is the multiple linear regression test using the classical assumption test, regression testing, and hypothesis testing. Based on the research results, it can be explained: 1) Partially, the number of banks does not influence but is significant on bank performance (-3.333 < 2.110; 0.004 < 0.05), the distribution of funds does not influence and is not substantial on bank performance (-1.992 < 2.110; 0.5063 > 0.05), and the source of funds influences and is significant on bank performance (3,440 > 2,110; 0.003 < 0.05); 2) Simultaneous positive and significant influence of the number of banks, distribution of funds, and sources of funds on performance (17.113 > 2.96; 0.000 < 0.05; 3) The bank performance variable has no relationship with the variable number of banks, distribution of funds with the figures shown being -0.753, -0.482 and has a relationship to the source of funds of 0.501