bluuebunny/crossref_metadata_2025 huggingface dataset:
RESEARCH ON TRAFFIC CONGESTION DETECTION FROM CAMERA IMAGES IN A LOCATION OF DA LAT
Authors: Luong Nguyen Thi
Published: October 2021

Many researchers are interested in traffic congestion detection and prediction. Traffic congestion occurs increasingly in many cities in Vietnam, including the city of Da Lat. This paper focuses on SVM, CNN, DenseNet, VGG, and ResNet models to detect traffic congestion from camera images collected at Nga 5 Dai Hoc, Da Lat. These images are labeled with the words traffic congestion or no traffic congestion. The experimental results have an accuracy of over 93%. The study is an initial contribution to a future system for predicting traffic congestion in Da Lat when the camera system is fully installed.
Der geologische Bau pleistozaner Inlandgletschersedimente Norddeutschlands
Authors: Grube F. , Voll­mer Th.
Published: October 2021

The geologic structure and genetic aspects of inland galcier sediments are described on examples from northern Germany. Different types of structures are demonstrated ranging from slight undulation to in­tense subglacial folding and shearing. Inland glacier sediments are called all deposits laid down and/or de­formed by inland glaciers. These sediments resting on glacially undeformed basement include lodgement till (at top) and below of it shear till, melt-out and deformation till. A fundamental tool of modern till stratigraphy is the knowledge of the geologic structure more than are petrography and geochemistry of moraines at present.
Glazialtektonik im Weichselglazial Schleswig ­Holsteins und ihre Beziehungen zur Morphologie
Authors: Prange W.
Published: October 2021

Detailed glaciotectonic studies have been conducted in the Weichselian glaciated area of Schleswig-Hol­stein in order to obtain a better understanding about the stratigraphy, the morphogenetic development and thus about the Pleistocene events towards the end of the last glaciation.
In general, an upper till discordantly overlies a lower till, which is partly cove'red with meltwater depos­its. The thin upper till cover is probably derived from the last ice readvance in the Oldest Tundra Time, the so-called »Fehmam-advance•, because artifacts found under this till belong to the Younger Hamburg Cul­ture.
Various ice tectonic structures such as block-faulted zones, overthrusted folds and folds were observed in these overridden strata. The different directions of the last glacial advance have been determined. The relationship between them and the interpretation of the morphology after Gripp (1952, 1954) is correlated and illustrated with field examples: It is possible to determine the direction of the ice flow from the mor­phology only in regions with strong and definite topography. However, in the gentler rolling regions with weaker and indistinct morphology the overridden strata may either be disturbed or undisturbed without perceptible changes in their palaeorelief. Therefore in these regions, the present day morphology is not the result of the last ice advance alone, but is due to a combination of the penultimate ice advance, the fol­lowing meltwater deposition, the last ice readvance and subsequent melting of dead ice.
The walrus, Odobenus rosmarus (L.), as a "Danish" faunal element
during the Weichsel Ice Age
Authors: Møhl Ulrik
Published: October 2021

Two recent datings of walrus skull fragments from the North Sea, giving the C-14 ages 24380±620 years
before 1950 and 30880± fil8 before 1950 respectively, show that as a fauna! element the walrus can be tra­ced back to 􀀖he time before the main thrust of the Weichsel Ice Age.
Clay mineral investigation of the Rhaetic - Jurassic - Lower Cretaceous sediments of the B0rglum 1 and Uglev 1 wells, Denmark
Authors: Schmidt Birthe J.
Published: October 2021

The clay mineral assemblages of the Rhaetic -Jurassic - Lower Cretaceous sequences from the Borglum 1 and U glev 1 wells have been investigated to evaluate the diagenesis of the sediments. Besides grain size analyses, the methods include X-ray diffraction analyses and scanning electron microscopy in combination with energy dispersive analyses.
The distribution of clay minerals essentially shows a rapid change from smectite to kaolinite dominance with increasing depth. Kaolinite dominates the older sediments below the lower part of the Haldager For­mation, including the Fjerritslev and Gassum Formations, while smectite dominates the younger sedi­ments above the upper part of the Haldager Formation, which includes Bream and Vedsted Formations. This change is primarily attributed to differences in the composition of the mineralogy and geochemical environment rather than to burial diagenesis. While some early diagenesis has taken place to form authi­genic kaolinite, thorough depth-dependent diagenesis can hardly be detected.
PENERAPAN APLIKASI MY JICT DALAM MENINGKATKAN USAHA TERMINAL PETI KEMAS DI ERA 4.0
Authors: Dewi Ratna Kurnia , Fakhrurrozi
Published: October 2021

Kajian tentang penerapan aplikasi My JICT dalam meningkatkan usaha terminal peti kemas di era 4.0. merupakan suatu bentuk peningkatan pelayanan di JICT dalam penanganan muatan petikemas akibat lamanya proses pengurusan dokumen custom clearance, serta kendala-kendala yang lain. Penelitian didasarkan pada penelitian kualitatif ini dilakukan di PT JICT dan beberapa perusahaan pengguna jasa dari PT JICT., dengan mendasarkan hasil penelitian dari wawancara sebagai data primer dan dari literasi dan kepustakaan sebagai data sekunder. Ruang lingkup permasalahan membahas mengenai : 1) Bagaimana penerapan aplikasi My JICT, serta kendala yang dihadapi oleh Jakarta International Container Terminal (JICT)?, 2) Bagaimana persepsi customers mengenai penggunaan aplikasi My JICT, dalam proses penanganan muatan kontainer oleh JICT di era 4.0?, dan 3) Bagaimana persepsi karyawan JICT mengenai penggunaan aplikasi My JICT dalam meningkatkan Usaha Terminal Petikemas?. Ada tiga klaster dokumen barang dan kapal dalam aplikasi My JICT mengintegrasikan siklus layanan utama, yaitu sistem E-billing, sistem Autogate, dan sistem elektronik Delivery Order (DO) online untuk integrasi dokumen kapal. Keuntungan dalam penggunaan aplikasi My JICT yaitu memudahkan proses pembayaran atas jasa kepelabuhanan khususnya untuk pemuatan kontainer, dapat mengatur cash flow sesuai dengan kebutuhan penanganan muatan kontainer, dari beberapa layanan terminal di dalam satu aplikasi dengan sederhana yang diintegrasikan secara baik dan tepat. Dengan diterapkannya sistem elektronik yang cepat dan efisien di pelabuhan, telah mendorong dan meningkatkan adanya peningkatkan penetrasi percepatan layanan antar lembaga, dan pelayanan elektronik pelabuhan 24 jam menjadi langkah awal dalam pelaksanaan pengoperasian pelabuhan yang modern dan handal di Indonesia.
ANALISIS POWER OF HYDROGEN DAN KESADAHAN FEED WATER BOILER GUNA MENINGKATKAN EFISIENSI BOILER DI PT. DJARUM KUDUS
Authors: Herry Widodo  , Ryan Saputra  , Puryadi
Published: October 2021

Pengolahan air umpan boiler digunakan sebagai umpan boiler. Penelitian ini bertujuan mengetahui nilai PH,Kesadahan, dan total disolved solve pada air umpan boiler dengan media air sumur di PT. DJARUM KUDUS, dengan acuan standar menurut SOC PT.Djarum Kudus. Metode penelitian penulis gunakan yaitu analisa kuantitatif. Metode analisa kuantitatif menganalisa sampel air sumur di laboratorium kimia dengan titrasi sehingga didapatkan konsentrasi Ca,Mg yang terlarut dalam sampel, sampel di ambil dari sumur 1 dan sumur 2 di PT.DJARUM Kudus. Serta analisa PH dan Kesadahan. Hasil penelitian menunjukkan : air umpan boiler sumur 1 dengan PH 9,40, dan kesadahan 2 ppm, dan air umpan boiler pada sumur 2 dengan PH 8,90, dan Kesadahan 1,8 ppm. didapat dari penelitian tersebut PH dari Sumur 1 tidak memenuhi standart yaitu 9,40 PH. Karena tingginya pH bisa mengakibatkan korosi pada dinding pipa boiler mengganggu transfer panas dan memperpendek umur alat. Sedangkan hasil analisa kesadahan pada air sumur 1 dan sumur 2 memenuhi SOC PT. Djarum Kudus.
Students’ Paraphrasing in the Literature Review Section of Research Proposal
Authors: Akbar Muhammad Taufiq
Published: October 2021

The objective of this qualitative study is to investigate the students’ paraphrasing in the literature review section of research proposal. Six English Department students, Universitas Negeri Gorontalo were selected as the respondents. The study reveals that the paraphrasing of three students falls under a moderate revision category, and the other three are in the category of near copy. Such a result is based on the results of the students’ paraphrasing and their understanding of the concepts of effective paraphrasing, namely comprehension of good paraphrasing, analytic reading skills and its correlation in applying paraphrasing strategies, and citation mechanics. On that ground, the study suggests that improving students’ concept of paraphrasing in reviewing the literature is a necessity. Related stakeholders are urged to help the students understand the idea of quality paraphrasing. Further research about paraphrasing to investigate other relevant issues and other textual borrowing mechanics is essential.
The Character of Rip van Winkle: Representation of Disappearing Cultural Identity
Authors: Baga Magdalena
Published: October 2021

Abstract ─ The purpose of this research is to explore how an ethnicity is represented in a story that has a historical setting and how this ethnic group was placed in American history. The short story of Washington Irving, "Rip Van Winkle", published in 1819, was very popular in America. This story was recycled in the form of stories for children, made into plays, etc. What Americans always remember about Rip Van Winkle character is his laziness. The story of "Rip Van Winkle" is traced through Stuart Hall's Representation theory. This theory states that representation can give meaning to an identity, and the New Historicism method is used to uncover that fictional stories are tied to the world that produced them. The result shows that Rip's character is a representation of Dutch ethnicity who felt losing their cultural identity. Rip's character in the story is a representation of Dutch New York ethnicity, and he was the main character in the story who was narrated as a lazy man. Thus, what always presents in America's memory is the lazy Dutch because of the representation of the character of Rip, but the other characters who were narrated less in the story are not remembered, even though they played a role in establishing America.
Metaphor in Students’ English Poems: A Psycholinguistic Analysis
Authors: Katili Adriansyah Abu
Published: October 2021

This research is aimed at finding how the students of English Department of State University of Gorontalo perceive the thing as revealed in the metaphor they used in their English Poem and, as well, interpreting the metaphor. This research was designed in qualitative research methodology. The subject of research was the poems written by the students in 2010. It is found that the students used metaphor to express their feeling. The metaphor reflects the students’ perception of the reality categorized in semantic fields. In terms of the intended meaning of the metaphor, the researcher inferred the meaning by finding the metaphor predications based on the researcher knowledge of the predication.
A rejtőzködő bűn és a büntető hatalom
Authors: Finszter Géza
Published: October 2021

Learning the past will acquire a procedural significance when some real event of the past would trigger legal consequences. In addition to criminal cases this can be realized in civil litigation, in administrative procedures of the public power, but examples can also be taken from the field of labour law. As criminalistics represent the science of reconstructing a past event, an extension of it to all legal fields can be reasoned. However, such a turn does not have taken place, the discipline of investigation remained within the sphere of criminal sciences. The article examines the causes of that.
A kriminalisztika bűnmegelőzési funkciója
Authors: Fenyvesi Csaba
Published: October 2021

Criminalistics is, in essence, mainly a practical and – to a sm aller extent – theoretical science of criminal investigation, in other words, it is a branch of criminal sciences that explores, creates, systemizes and applies – within normative legal frames - means and methods for the detection (prevention) and proof of crime. This study analysis the crime prevention function and fields of criminalistics and shows up present and future potential criminalistic preventive possibilities, methods.
Going virtual for research training during the COVID-19 pandemic and beyond: e-SORT IT
Authors: Davtyan Hayk , Davtyan Karapet , Harries Anthony D , Reid Anthony , Aslanyan Garry , Khogali Mohammed , Zachariah Rony
Published: October 2021

The Structured Operational Research and Training Initiative (SORT IT) model has contributed to building research capacity and has produced evidence for improving public health program performance in countries with limited research capacity. The model involves hands-on mentorship and consists of three modules/weeks. It is recognized to be an innovative research capacity building model. In a world changed by COVID-19, where bringing people together is not viable, an innovative, interactive, web-based, knowledge-transfer platform (e-SORT IT) for virtual implementation of SORT IT modules was created. The platform design imitated the residential course as closely as possible with the same lectures, plenary sessions, and breakout rooms. Despite the challenges, the platform performed well and even though participants and mentors were located in eight different time zones, the course was successful; 90% of participants achieved their milestones and 10 manuscripts were successfully completed. Participant evaluation revealed a satisfaction level that was nearly equivalent to the residential module. However, mentor evaluation indicated a number of shortcomings including capacity building, professional networking, communication, engagement, and contribution by participants, as well as overall module success. In conclusion, COVID-19 stimulated the creation of the e-SORT IT platform that provided a functional alternative to the residential version. Despite the limitations of reduced capacity building and networking, the e-SORT IT platform should be considered a success – it delivered the goods. This is an example of innovation and flexibility, two attributes that are sorely needed to maintain activities during the pandemic and beyond.
Neuro-anesthetic Management of Craniotomy-surgery in Removal Tumor Multiple Meningioma Patients: A Case Report
Authors: Kulsum Kulsum , Suryadi Taufik
Published: October 2021

AIM: The aim of following paper is to present the case anesthesia management of neuro-surgery in removal tumor multiple meningioma patients. METHODS: The method of this study was a case report. It was reported that a patient aged 50 years complained of spasms of full body spasms since 10 minutes before admission to the hospital. Complaints were accompanied by eyes glaring upward, seizure duration 20 minutes, after convulsions of unconscious patients, patients with previous tumor history, 3 years ago, patients with postoperative meningioma tumor removal. Patient diagnosed with multiple meningioma who planned to undergo craniotomy surgery to remove the tumor. MAIN FINDING: ASA 3 physical status with neurologic deficits. The patient is performed under general anesthesia with intubation. Induction performed by fentanyl, propofol and rocuronium. The operation lasted 3 hours. Postoperatively, the patient was admitted to the Intensive Care Unit for 2 days before moving into the room. Anesthetic treatment and regulation of physiological factors have a major impact on brain tissue. The anesthetist must have knowledge of the effects of drugs and other manipulations in order to achieve good surgical results. RESULT: Anesthetic management for meningioma cases has several special matters that are important to carry out. The brain tissue is covered by the cranium bone. Because of the continuous relationship of blood flow and brain tissue volume, the risk of bleeding and edema is very high. Without a proper anesthetic approach, it can increase the risk of edema and cerebral hemorrhage due to surgical manipulation.
The Effect of Topical Corticosteroid Time of Application on Fibroblast and Type III Collagen Expression in Oryctolagus cuniculus with Deep Dermal Burn Wound (As an Indicator for the Best Time to Start Topical Corticosteroid Application in Preventing Hypertrophic Scar)
Authors: Lumintang Loelita , Adnyana I Made Suka , Hamid Agus Roy , Sanjaya Hendra , Golden Nyoman , Astawa Putu , Darmajaya Made , Sumadi I Wayan Juli
Published: October 2021

Background: Hypertrophic scar is an abnormal scar that causes physical deteriorations, psychological problems, and aesthetic issues. An excessive number of fibroblasts and collagen III expressions are histopathology indicators for the hypertrophic scar. The role of topical corticosteroids in suppressing inflammation and hypergranulation had widely demonstrated in previous studies. However, there is no study related to the application of topical corticosteroids as prevention of hypertrophic scars from burn wound found. Hence, this study aimed to examine the evidence of the effects of corticosteroid topical in decreasing the number of fibroblasts and type III collagen expression and the best time to start its application in preventing hypertrophic scars. Methods: This randomized experimental post-test only study involved 54 deep dermal burn wounds on the ventral ear of female Oryctolagus cuniculus that distributed into three groups based on the healing phases. Each group consisted of treatments and controls. Corticosteroid topical application on the first treatment group (inflammatory phase group), the second group (proliferation phase group), and the third group (remodelling phase group) was started on day 3, on day 10, and day 21, respectively. Specimens taken on day 35. Haematoxylin-Eosin and Immunohistochemically staining performed to measure the number of fibroblasts and type III collagen and to observe the epithelization and inflammation process. Results: The number of fibroblasts significantly decreased in the second treatment group (p =0.001) and followed by the first group (p = 0.016), but no significant decrease found in the third group (p = 0.430). The type III collagen decreased significantly in the second treatment group (p = 0.000) and followed by the third group (p = 0.019), but no significant decrease found in the first group. There was no statistically different number of fibroblast and type III collagen discovered between the controls. Complete epithelization found in all groups. Also, no ongoing inflammation found in all groups.  Conclusion : Topical corticosteroids on deep dermal burn wound revealed to be effective in reducing the number of fibroblasts and type III collagen with no healing disruption. The proliferation phase found to be the best time to start the application of topical corticosteroids.
Comparative evaluation of cystatin C and neutrophil gelatinase-associated lipocalin in patients with thalassemia major versus thalassemia intermedia
Authors: Mohammed Marwah , Mohammad Jehan , Fathi Zainab , Al-Hamdany Muzahim , Alkazzaz Nasih
Published: October 2021

Kidney disorders are long-term complications in thalassemia patients, especially with the high life expectancy of these patients. Proper evaluation of kidney impairment in β-thalassemia patients can be difficult due to higher intake of iron chelators, resulting in renal impairment. Early biomarkers of renal disease are used for the diagnosis of tubular and glomerular abnormalities. The current study was conducted on 88 individuals, 25 healthy people and 63 β-thalassemia patients. Circulating levels of urea, creatinine, cystatin C and neutrophil gelatinase-associated lipocalin were measured in all groups. Compared to healthy control, patients with thalassemia major and intermedia showed a significant increase in both cystatin C and NGAL levels, with no effects on creatinine levels. Furthermore, urea levels were markedly higher in patients with thalassemia major compared to control. As early renal dysfunction markers, cystatin C and NGAL should be routinely evaluated in thalassemia patients major and intermedia.
Feather mites (Acariformes, Astigmata) from marine birds of the Barton Peninsula (King George Island, Antarctica), with descriptions of two new species
Authors: Han Yeong-Deok , Mironov Sergey V. , Kim Jeong-Hoon , Min Gi-Sik
Published: October 2021

We report on the first investigation of feather mites associated with birds living on the Barton Peninsula (King George Island, Antarctica). We found seven feather mite species of the superfamily Analgoidea from four host species. Two new species are described from two charadriiform hosts: Alloptes (Sternalloptes) antarcticussp. nov. (Alloptidae) from Stercorarius maccormicki Saunders (Stercorariidae), and Ingrassia chionissp. nov. (Xolalgidae) from Chionis albus (Gmelin) (Chionidae). Additionally, we provide partial sequences of the mitochondrial cytochrome c oxidase subunit I (COI), which was utilized as a DNA barcode, for all seven feather mite species.
Impact of COVID-19 Pandemic on Nurses: Where is the Financial Safety Net?
Authors: Millenbach Linda , Crosby Frances , Niyirora Jerome , Sellers Kathleen , Maneval Rhonda , Pettis Jennifer , Brennan Noreen , Gallagher Mary , Michela Nancy , Elliott Deborah
Published: October 2021

The COVID-19 pandemic placed many nurses in financial distress. Nurses House, Inc. provided nurses with financial assistance through an emergency grant supported by the American Nurses Foundation. In a three-month period between April 2020 till July 2020, Nurses House, Inc. distributed $2,734,500 to a total of 2,484 qualified grantees from across the United States. This article offers a brief review of literature to provide context about the guiding framework of the grant, Watson’s Theory of Human Caring, as an essential tenet to nursing and to the mission of Nurses House, Inc, and the financial impact of the pandemic. We discuss the methods, data analysis, and results of our study that analyzed demographic information from the applications of grant recipients. Regression analysis showed that regardless of income levels, nurses experienced financial distress. The discussion considers our findings in relation to such areas as age and full-time or part-time work status of grantees; reasons to apply, such as testing positive for COVID=19 (78%), work mandated quarantine (16%) and caring for a family member (6%); and study limitations. The conclusion offers implications for practice based on our analysis, which demonstrated that financial safety nets are both essential and helpful for nurses in times of crisis.
COVID-19 in Communities of Color: Structural Racism and Social Determinants of Health
Authors: Flagg Lakisha , Campbell Lisa
Published: October 2021

Black, Indigenous, People of Color (BIPOC) communities have a disproportionally high prevalence of COVID-19 and, subsequently, a higher mortality rate. Many of the root causes, such as structural racism and the social determinants of health, account for an increased number of preexisting conditions that influence risk for poor outcomes from COVID-19 as well as other disparities in BIPOC communities. In this article we address Structural Factors that Contribute to Disparities, such as economics; access to healthcare; environment and housing concerns; occupational risks; policing and carceral systems effects; and diet and nutrition. Further, we outline strategies for nurses to address racism (the ultimate underlying condition) and the social and economic determinants of health that impact BIPOC communities.
Increasing Quality and Patient Outcomes with Staff Engagement and Shared Governance
Authors: Brennan Deborah , Wendt Lori
Published: October 2021

The shared governance structure is a nursing practice model which is a hallmark of engaging the front line team into the role of leading practice excellence. The main principles of shared governance include ownership, accountability, empowerment, team building, leadership, innovation, autonomy, and practice equity. Combining these key shared governance principles with formal models can drive sustainable action planning for improvement. This article offers an exemplar describing how we improved shared governance in a community hospital setting. After evaluating findings from a gap analysis, we incorporated guiding frameworks such as the A3 action planning process; the Plan, Do, Check, Act cycle; and Lean methodologies to increase nursing engagement in the shared governance process. Clinical nurses and interdisciplinary teams developed action plans for quality and patient satisfaction improvements. We describe specific improvements to our process, offer examples of our improved outcomes, and discuss essential shared governance factors that were critical to our successes.
Experiences of Burnout Among Nurse Anesthetists
Authors: Vells Brian , Midya Vishal , Prasad Amit
Published: October 2021

Recent and mounting evidence indicates burnout among healthcare providers in the United States has been steadily rising over the last decade. Review of the literature has indicated that burnout affects provider clinical performance, professionalism, quality, incidence of medical errors, and intention to stay in the profession. Burnout has been shown to impact provider quality of life. However, education focused on coping skills can reduce burnout amongst providers. This article describes a quality improvement project conducted to determine the effect of a burnout awareness and coping skills program to decrease burnout among nurse anesthetists at a level one trauma center. The educational program provided information that helped staff to identify signs and symptoms of burnout and offered strategies to reduce burnout. We describe the project methods, and results, which suggested a significant decrease in participants’ levels of the emotional exhaustion component of burnout following participation in the program. We offer discussion about the clinical significance of our findings, note project limitations, and conclude with implications for research and practice.
The Art of Nursing Becomes a Celebration of Nurses
Authors: Motter Tracey , Hassler David , Anthony Mary
Published: October 2021

Although the art and science of nursing both complement nursing practice, the science aspect is most often emphasized. The art of practice, however, may best capture the essence of nursing. To recognize the 50th anniversary of a college of nursing, faculty, staff, and alumni participated in creation of a community poem, entitled “Some Days.” As the COVID-19 pandemic brought public awareness to the contributions of nurses, the art of nursing was evident in the many ways that nurses cared for both patients and families. The reflective process took on new meaning, celebrating nurses with poetry and giving voice to the emotional demands of nursing. In this article, we offer a brief historical overview of the art and science of nursing, and discuss the collaborative process that led to the creation of the poem and its installation as a public work of art. This collective poem weaves together the reflections of many individuals, unveils raw emotions, and provides a deeper understanding of meaningful connections between patients and nurses through the powerful imagery of poetry. In our conclusion, readers are invited to read the poem, “Some Days,” and share their passion for nursing by adding to this open community poem that celebrates the unique work of nurses.
Undergraduate Nursing Students' Stress and Fear of Missing Out
Authors: Çevik Aktura Seher , Özden Gürkan , Çıtlık Sarıtaş Seyhan
Published: October 2021

Background:

This descriptive study analyzed the stress in nursing education and the fear of missing out.

Method:

This study was conducted at a public university in eastern Turkey and included 1,119 undergraduate nursing students. Result: Findings indicated there was no statistically significant relationship between the levels of stress experienced by students during their nursing education and their fears of missing out.

Conclusion:

In light of these findings, recommendations include identifying the factors leading to stress and fear of missing out for undergraduate nursing students and then developing potential strategies to help allay nursing students' stress and fears.

[
J Nurs Educ
. 2021;60(10):559–565.]
Undergraduate Student Stress, Classroom Engagement, and Self-Directed Learning Postcurricular Revision
Authors: Rossi Rose A. , Krouse Anne M. , Klein Jean
Published: October 2021

One way of promoting student success in a nursing program is through curricular revision. However, significant curricular revision coupled with a simultaneous move to active learning strategies can have an impact on the educational and emotional well-being of students. This descriptive correlational study examined student stress, engagement, and self-directed learning in a convenience sample of junior-level nursing students (
N
= 164) after a transition to a new curriculum and active learning methods. The researchers identified moderate stress levels in students, which affected both classroom engagement and self-directed learning. Select demographic variables also impacted study outcome variables. The findings of this study highlight the need for interventions to promote stress reduction and self-care for students. Faculty and curriculum committees must remain vigilant when restructuring the curriculum ladder to decrease the academic burden on already stressed students.

[
J Nurs Educ
. 2021;60(10):566–569.]
Aging Matters Through the Years: A Retrospective
Authors: Sorrell Jeanne M.
Published: October 2021

The goal of the Aging Matters column is to address important issues related to geropsychiatry and the well-being of older adults. This article offers reflections on columns from the past 15 years and how the aging process has changed in issues related to aging and technology, aging healthfully, end-of-life issues, caregivers for older adults, and growing old in American society. To promote successful aging, we need to hear stories of what it is like to grow old in America. We also need research to better understand the aging process and what is needed for successful aging. In addition, we need policies and resources that help ensure well-trained caregivers who can protect vulnerable older adults and help them age healthfully. Stories of individuals, research, and health care policies need to be connected to create meaningful changes within the health care system. [
Journal of Psychosocial Nursing and Mental Health Services, 59
(10), 7–11.]
Understanding Nursing Home Residents' Lives Through the Lens of Selection, Optimization, and Compensation Theory
Authors: Runyan Amanda M. , Medvene Louis J. , Coleman Carissa K. , DiLollo Anthony
Published: October 2021

The current study examined the importance of personal goals to residents; assessed whether goal-related behavior was associated with mental health factors (i.e., depression, experiential avoidance, and quality of life); and explored residents' use of selection, optimization, and compensation (SOC) strategies. Interviews were conducted with eight residents at a nursing home along with paper-and-pencil measures of mental health factors. Transcripts were coded first for goal content and subsequently analyzed using an exploratory qualitative method. Most residents (five of eight) denied having goals. Experiential avoidance and depression were significantly negatively correlated with goal content; quality of life was significantly positively correlated with goal content. Eleven themes derived from exploratory analysis suggest SOC processes were important in residents' lives. The study demonstrated the relevance of SOC for residents' quality of life. The potential for developing person-centered interventions to evoke implicit goals and facilitate attainment is discussed. [Research in Gerontological Nursing, 14(6), 277–284.]
Use of Natural Pyrophyllite as Cement Substitution in Ultra Performance Polypropylene Fiber Concrete
Authors: Mansour Sabria Malika
Published: October 2021

The present work investigates the use of an alumino-silicate material, the pyrophyllite as cement substitution, synthetic polypropylene fibers and binder to create an unusual ultra-performance fiber concrete; new composite, which offers a wide field of possible use in construction industry. Effect of pyrophyllite on the physical-mechanical properties is analyzed. One reference fiber concrete without pyrophyllite and three fiber concretes containing 10%, 20%, 30% of pyrophyllite were elaborated. Results show that the pyrophyllite affects the characteristics of the concrete. Indeed, in the hardened state, the density of fiber concrete decreased with pyrophyllite rate increasing. Moreover, the use of pyrophyllite slows down the hardening process of concrete, consequently producing at early ages, compressive, flexural and tensile strengths and elastic modulus of concretes approaching without exceeding those of the reference fiber concrete. The fiber concretes are also considered to be of good quality. It seems that the rate of 10 % of pyrophyllite generates the best physical-mechanical performances that approach those of the reference fiber concrete. The use of pyrophyllite as a cement substitution is beneficial since it can help to decrease the production of cement; the amount of CO2 released and protects the environment.
Application of Cellulosic Fibrous Material from Agro Waste as Filtrate Loss Modifier in Aqueous Mud-Morphology at HTHP Conditions
Authors: Okoro Emeka Emmanuel , Sanni Samuel E. , Okafor Ikechukwu S. , Igwilo Kevin Chinwuba , Okolie Sociis T.A. , Emetere Moses E.
Published: October 2021

Controlling the filtration characteristics of any drilling fluid does not only include the control of the filtrate volume penetrating into the formation; but also the ability of the mud to deposit a thin low-permeability filter cake on the wall of the wellbore quickly. The permeability of the filter cake is very dependent on the particle size because when small size particles are used, the permeability decreases, because of the fact that colloidal particles get packed very tightly. This study investigated the filtration and filter cake characteristics of water-based mud (WBM) using fibrous cellulose from Tiger Nut waste and the guar gum. American Petroleum Institute (API) Recommended Practice Standard Procedure for Field Testing Drilling Fluids, API RP 13B-1 was applied during the analysis. Statistical analysis of the experimental data was conducted and the R2 value (0.99) showed that the experimental method adopted was replicable. Mud samples B2 and C2 gave an optimum result and their mud cakes developed under High-Temperature High-Pressure (HTHP) condition were dried and further analyzed with scanning electron microscope (SEM). The results showed that the filter cakes SEM structure for cellulosic fibrous from agro waste and guar gum exhibits similar characteristics; and the mud cakes was firm after soaking with 15% HCl for thirty minutes but started dissolving after one hour. The SEM analysis inferred that the filter cake morphology shows a good particle-pore interlocking for sample C2 than B2.
Cutting Edge: Lung-Resident T Cells Elicited by SARS-CoV-2 Do Not Mediate Protection against Secondary Infection
Authors: Roberts Lydia M , Jessop Forrest , Wehrly Tara D , Bosio Catharine M
Published: October 2021

Immunity to pulmonary infection typically requires elicitation of lung-resident T cells that subsequently confer protection against secondary infection. The presence of tissue-resident T cells in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent patients is unknown. Using a sublethal mouse model of coronavirus disease 2019, we determined if SARS-CoV-2 infection potentiated Ag-specific pulmonary resident CD4+ and CD8+ T cell responses and if these cells mediated protection against secondary infection. S protein–specific T cells were present in resident and circulating populations. However, M and N protein–specific T cells were detected only in the resident T cell pool. Using an adoptive transfer strategy, we found that T cells from SARS-CoV-2 immune animals did not protect naive mice. These data indicate that resident T cells are elicited by SARS-CoV-2 infection but are not sufficient for protective immunity.
Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
Authors: Pontico Mariano , Frantellizzi Viviana , Cindolo Luca , De Vincentis Giuseppe
Published: October 2021

To the Editor, we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered expression of miRNAs in cancer pathogenesis represents a well-consolidated knowledge in the current literature. More specifically, both miR-212 and miR-132 regulate subsets of genes involved in tumor progression in several tumor cell types as PCa, proving a central role in tumorigenesis, cell adhesion, and angiogenesis. In addition, a strong association between miR-132 expression and high Gleason score PCa has been lately depicted [...].
Studying the electrolyte changes in ileal urine at the time of radical cystectomy and ileal conduit diversion
Authors: Atta Mohamed Adel , Abou Youssif Tamer , Kotb Ahmed
Published: October 2021

To the Editor, Radical cystectomy (RC) for bladder cancer is a life-changing surgery, associated with high morbidity and mortality rate. Ileal neobladder seems as an attractive way for urine management post cystectomy but would carry the risk of retaining urine in the ileal pouch for a long time, resulting in serum electrolyte changes, that may add to the patients’ morbidity. EAU guidelines recommend against ileal neobladder for patients with liver and renal disorders, as well as for patients > 80 years old [...].
Anticonvulsive evaluation and histopathological survey of thalidomide synthetic analogs on lithium-pilocarpine-induced status epilepticus in rats
Authors: Amanlou Arash , Eslami Faezeh , Shayan Maryam , Mortazavi Pejman , Dehpour Ahmad Reza
Published: October 2021

Background and purpose:

Status epilepticus is a severe neurological disorder that can be life-threatening. Thalidomide and its analogs have shown promising results to confront pentylenetetrazole-induced seizures. This study aimed to evaluate the potential effects of three synthesized thalidomide derivatives on lithium-pilocarpine-induced status epilepticus.

Experimental approach:

To induce status epilepticus, rats received lithium chloride (127 mg/kg, i.p.) and pilocarpine HCl (60 mg/kg, i.p.) 20 h after lithium chloride injection. Thirty min before pilocarpine HCl administration, rats received hyoscine N-butyl bromide (1 mg/kg, i.p.) and concurrently one of the test compounds (5B, 5C, and 5D), diazepam, thalidomide, or vehicle (4% DMSO) to evaluate their anti-epileptic effects. Epileptic seizures scores were assessed through the Racine scale. Twenty-four h after injection of pilocarpine, brain samples were extracted for further histopathological evaluation.

Findings/Results:

Results revealed that among tested compounds (5B, 5C, and 5D), only compound 5C (1 mg/kg) exhibited excellent anti-epileptic activity comparable to diazepam (10 mg/kg). Compound 5D (100 mg/kg) only demonstrated comparable anti-epileptic activity to thalidomide (1 mg/kg). Compound 5B did not have any anti-epileptic activity even at the dose of 100 mg/kg. The histopathological survey showed that compound 5C has more neuroprotective effects than diazepam and thalidomide in the cortex of the brain. In the cornu ammonis 1 region, thalidomide had higher protective properties and in the cornu ammonis 3 and dentate gyrus areas, diazepam had higher efficacy to prevent necrosis.

Conclusion and implications:

Compound 5C is a good candidate for further studies regarding its potency, compared to thalidomide and diazepam.
Artemether-loaded nanostructured lipid carriers
Authors: Rahnama Vahid , Motazedian Mohammad Hossein , Mohammadi-Samani Soliman , Asgari Qasem , Ghasemiyeh Parisa , Khazaei Meisam
Published: October 2021

Background and purpose:

Cutaneous leishmaniasis is a global health problem. The discovery of new and highly efficient anti-leishmanial treatments with lower toxicity is globally needed. The current study was carried out to evaluate the anti-leishmanial effects of artemether (ART) and ART-loaded nanostructured lipid carriers (ART-NLCs) against promastigotes and amastigotes of Leishmania major.

Experimental approach:

Solvent diffusion evaporation technique was applied to prepare ART-NLCs. These nanoparticles were characterized using a particle size analyzer (PSA), transmission electron microscopy (TEM), and dynamic light scattering (DLS). The antiparasitic activity on amastigote was assessed in J774 cell culture. The drug cytotoxicity on promastigote and macrophage was assessed using the MTT technique after 24 and 48 h and compared with NLCs, ART, and amphotericin B, as the control agents. The selectivity index was calculated for the agents.

Findings/Results:

The DLS and PSA techniques confirmed that ART-NLCs were homogenous in size with an average diameter of 101 ± 2.0 nm and span index of 0.9. The ART-NLCs significantly heighten the anti-leishmanial activity of ART (P < 0.001). The IC50 values of ART and ART-NLCs on promastigotes after 24 and 48 h were 76.08, 36.71 and 35.14, 14.81 μg/mL, respectively while they were calculated 53.97, 25.43 and 20.13, 11.92 for amastigotes. Also, ART-NLCs had the lowest cytotoxicity against macrophages. Furthermore, among the agents tested, ART-NLCs had the highest selectivity index.

Conclusion and implications:

ART-NLCs had lower cytotoxic effects than ART and amphotericin B, also its selectivity index was significantly higher. Based on the findings of the study, this formulation could be a promising candidate for further research into leishmaniasis treatment.
Attenuating effects of allantoin on oxidative stress in a mouse model of nonalcoholic steatohepatitis
Authors: Hamidi-zad Zeinab , Moslehi Azam , Rastegarpanah Maryam
Published: October 2021

Background and purpose:

Nonalcoholic steatohepatitis (NASH) is considered a common and serious liver disease, which develops into cirrhosis, fibrosis, and even hepatocellular carcinoma. Oxidative stress is identified as an important factor in the induction and promotion of NASH. Allantoin is a natural and safe compound and has notable effects on lipid metabolism, inflammation, and oxidative stress. Therefore, this study was aimed to assess the role of allantoin on the oxidative stress and SIRT1/Nrf2 pathway in a mouse model of NASH.

Experimental approach:

C57/BL6 male mice received saline and allantoin (saline as the control and allantoin as the positive control groups). NASH was induced by a methionine-choline deficient diet (MCD). In the NASH-allantoin (NASH-Alla) group, allantoin was injected for 4 weeks in the mice feeding on an MCD diet. Afterward, histopathological, serum, oxidative stress, and western blot evaluations were performed.

Findings/Results:

We found NASH provided hepatic lipid accumulation and inflammation. Superoxide dismutase (SOD) and glutathione (GSH) levels decreased, lipid peroxidation increased, and the expression of SIRT1 and Nrf2 downregulated. However, allantoin-treatment decreased serum cholesterol, ALT, and AST. Liver steatosis and inflammation were improved. Protein expression of SIRT1 and Nrf2 were upregulated and SOD, CAT, and GSH levels increased and lipid peroxidation decreased.

Conclusion and implications:

It seems that the antioxidant effects of allantoin might have resulted from the activation of SIRT1/Nrf2 pathway and increase of cellular antioxidant power.
Case Report: Home-based Management of Severe COVID-19 with Low-dose Tofacitinib
Authors: Sharma Ashish , Ali Mohammad
Published: October 2021

Human lives and nations’ economies have been adversely affected worldwide by the COVID-19 pandemic. The hyperinflammatory state associated with the disease may be related to mortality. Systemic glucocorticoid is the first-line therapy for cytokine storm. Various immunomodulatory drugs such as tocilizumab and baricitinib have been used in those not responding to glucocorticoid monotherapy. Amid the peak crisis of COVID-19 in India, there was an extreme paucity of medications, oxygen, and hospital beds. We describe three patients with COVID-19 who received low-dose tofacitinib (an oral Janus kinase inhibitor) in addition to moderate-dose glucocorticoid. These patients were treated at their homes, as the hospitals were short of beds. Rapid reduction in hypoxemia along with gradual resolution of other signs of the disease were observed. The results are reassuring regarding the feasibility of managing of severe COVID-19 outside the hospital setting when healthcare resources are overwhelmed by pandemic-related caseload.
A Mediaeval Teaching Aid. An Analysis of One Page from the Manuscript by Jakub of Piotrków
Authors: Masłej Dorota
Published: October 2021

The purpose of this paper is to characterise page 190v of the manuscript preserved in the Jagiellonian Library (shelfmark 1297). The foregoing research has considered the page as a separate item, while the present study poses new questions concerning the writer’s intention, the function of the page, and its possible status.

The main part of the paper is an attempt to reconstruct the sequence of writing the elements of the layout, or page composition, paying special attention to the relations between them. Reconstructing the probable sequence of writing the texts on the analysed page allows the proposal of a hypothesis of how the author (known as Jakub of Piotrków, the Canon of Płock) worked on it. The analysis shows that the author’s intention could have changed as subsequent elements were being written on the page.

Certain elements of the page were selected for use depending on the audience of the lecture and its purpose. The latest research that linguistic relics like this one, closely bound up with orality of the mediaeval language, are not (were not) complete works in their final shapes, but rather texts in statu nascendi. The text discussed is an example of a genuine teaching aid that served the writer, Jakub of Piotrków, and probably later clergymen in ministering.