bluuebunny/crossref_metadata_2025 huggingface dataset:
FINGERPRINT AUTHENTICATED SECURE ANDROID NOTES
Authors: Agrawal Manish , Shah Saloni , Sah Anubha , Sahan Subrata
Published: August 2022

This Venture permits the clients to store individual notes in android portable utilizing unique mark verification. Android notes are the notes wherein one can store individual data. Individual data isn't making sure about to store in android telephones. Be that as it may, it will be smarter to store the notes with some sort of validation gave to it. The use of biometric as a distinguishing proof and acknowledgment measure fills a significant need in light of the fact that the headway of data innovation has coupled the requirement for high security or passwords. This is done to keep away from the danger to discover or still. Unique mark scanners can be utilized to recognize one scanner from another because of the exceptional examples. The surface example creates the hand math for made sure about and confirmed admittance control and it is the genuine substitute for passwords and identifiers in correlation with the current strategy biometric attributes for example unique mark accomplish real close to home ID. Fingerprint authentication is a secured biometric feature through which we can secure any data.so our Note application will be secured with Fingerprint authentication which makes this secured and private app. Users can use this note app for their private use keeping their fingerprint as security to access the app. Only the owner of the phone who has access to their phone can access this app which will make this app highly secured. Keywords: Fingerprint Authentication, Android Notes, Security, Biometric Application.
MILLENNIALS ON SOCIAL MEDIA AND CYBER SECURITY
Authors: Sehgal Dharna , Vaish Arti
Published: August 2022

In the modern day social media has become the most essential aspect in the modern society. These web based programmes help mellennials to interact in the society with their friends, family and even with strangers, which is why understanding internet is extremely important. As much as a good time they have on the internet they do get in trouble sometimes, where cyber security plays and important role. This paper aims on how the generation Y has to have a better understanding of the internet where they know what is good and bad for them, what is right or wrong for them. Having a good and protected environment on the web will help the youngsters to have a safe place to be in. Since internet’s instantaneous information, the broad reach of media influence makes it a glam space for generation Y, This research paper helps in explaining how social media is helping the young minds in their mind programming and how they have an impact over them, It also focuses on elaborating hoe o be safe on the web,keeping in mind all the instances which have had happened with youngsters on the internet.
EMERGING THREATS IN CYBER SECURITY
Authors: Raj Anukriti , vaish Arti
Published: August 2022

The growth of the Internet in the connections has led to a significant growth of cyber attack cases often with heavy outcome towards the globe. Malware is the primary choice of weapon to carry out malicious intent in the cyberspace, either by exploitation in to existing vulnerabilities or utilization of unique characteristics of emerging techniques. The development of more innovative and effective malware defense mechanisms has been regarded as an urgent requirement in the cyber security community. To assist in achieving this goal, we first present an over view of the most exploited vulnerabilities in existing hardware, software, and network layers.
THE MAJOR INTERNAL CHALLENGES OF THE FAILED PEACE-BUILDING PROCESS OF AFGHANISTAN
Authors: Lewal Rahmatullah , Akundzadah Obaidullah
Published: August 2022

In this paper, I want to explore the internal challenges of peace building in Afghanistan. The faction groups who are the major shareholders of the current government are considered one side and Taliban are the other side of the problem for peace in Afghanistan. In addition, land-mafia, corruption, weak economy divided society are the other core factors. Here in this paper we discuss the role of faction groups and other factors excluding Taliban.
IMAGE PROCESSING USING K MEANS CLUSTERING AND EUCLIDEAN DISTANCE METHOD
Authors: Parihar Rahul , sawhney Satvik , Vaish Arti , Verma Sherry
Published: August 2022

- Image processing refers to the processing of images, which includes many different techniques that are used till we reach our goal. The processing output can either be in the form of an image, or a feature of the given image. This can be used for decision making and a more comprehensive image analysis. The Image compression process is a variation of data compression that is used on images without affecting their quality. Reduced size of the file makes sure that a lot of images can be put in a certain amount of memory / disk space. Processing also decreases the required time for the images to travel over the Internet or to be downloaded from different web pages. K - means clustering using Euclidean distance method includes vector quantization, which is originally a part of signal processing. It is very popular in cluster analysis for mining data. In this Project, we are using Image compression and segmentation algorithms using K – means clustering and Euclidean Distance method and many more algorithms used to process images.
OPTIMIZATION OF BRAND MARKETING STRATEGY OF INTELLIGENT TECHNOLOGY UNDER THE BACKGROUND OF ARTIFICIAL INTELLIGENCE
Authors: Jain Aastha , Jain Sakshi , Vaish Arti
Published: August 2022

With the progress of Internet technology and the rapid development of artificial intelligence, intelligent technology products rapidly grow up. However, influenced by many factors, the marketing status of this kind of product in recent years is not ideal, for example, big data leakage and other issues. Especially in recent years, because of the greater market competition, the marketing of intelligent technology brands is facing greater problems. i.e. purpose of this study is to analyze the current situation of brand marketing of intelligent technology under the background of artificial intelligence and propose the optimization strategy of brand marketing of such products, so as to promote the continuous improvement of brand marketing effect of intelligent technology. Based on artificial intelligence and the concept of brand marketing, through intelligent technology brand marketing investigation and experiment, the intelligent technology brand marketing status and current problems are analysed from marketing, product type, and product price, three-angle analysis of the factors that influence the marketing and Internet marketing, product quality, product pricing, and product development is put forward from the four angles of specific strategy of optimization of smart technology products’ brand marketing. i.e. experimental results show that the year-on-year growth rate of smart technology brand turnover is decreasing at the present stage. i.e. increase rate of the turnover in 2019 is only 3.24%, far lower than that in 2015, and the growth rate of the turnover decreases by about 33%. At present, there are many problems in the marketing strategy of intelligent technology brands, and the optimization of marketing strategy is an urgent problem to be solved.
Dampak Struktur Modal dan Profitabilitas Terhadap Nilai Perusahaan Sektor Properti, Real Estate dan Konstruksi Bangunan
Authors: Buchari Imam
Published: August 2022

This study aims to determine whether the capital structure (DER) and profitability (ROE) have an impact on the Company Value (PBV) of the property, real estate and building construction sectors listed on the Indonesia Stock Exchange (BEI) for the 2014-2018 period. The research method used is Time Series from 2012-2018 and the number of Cross Sections as many as 10 companies, with the ex post facto method. The data presented annually are obtained from annual reports and financial reports of 10 property, real estate and building construction companies listed on the Indonesia Stock Exchange. This study uses a panel effects data regression model with a fixed effect model as a result of selecting the best regression model. Based on the results of the analysis, it can be concluded that DER partially has a positive and significant influence on firm value (PBV). To increase firm value, all companies in this sector are advised to strengthen their capital structure by increasing DER. Although most of these companies have DER> 1x, the results of the research show the positive influence shown by DER on PBVR, this means that the use of corporate debt to increase company equity is still quite controlled, so that the financial leverage of companies in this sector is still quite safe in using debt. company to increase company value. The company still has the potential to increase firm value by increasing the company's DER as long as the total debt does not exceed the company's total equity. then ROE partially has a positive and significant effect on Firm Value (PBV). So that to increase profitability is done by increasing the ROE indicator so that the Firm Value (PBV) can increase. Increase ROE in various ways, such as increasing company efficiency, reducing non-essential costs, maximizing the company's equity capacity and developing strategies to increase the company's net income so that it can increase the Company's ROE. DER and ROE simultaneously have a significant effect on Firm Value (PBV).

Keywords:  Capital Structure, Firm Value, Debt to Equity ratio, Price to Book Value, Profitability, Return on Equity

 
Pengaruh Pengalaman Kerja dan Motivasi Kerja Terhadap Produktivitas Kerja pada PT. Tip Top Ciputat
Authors: Khair Oki Iqbal , Astuti Widia
Published: August 2022

The purpose of this research is to find out and analyze the effect of work experience on work productivity, to know and analyze the effect of work motivation on work productivity, and to know and analyze the effect of work experience and work motivation together on employee productivity PT. Tip Top Wholesale Ciputat.
 The research method used by the author is a quantitative descriptive method that aims to determine the effect of two or more variables, where this approach provides a description of the problem to look for the influence between variable X1 (Work Experience) and variable X2 (Work Motivation) with variable Y (Work Productivity ) then hypothesis testing is performed to determine whether the proposed hypothesis is accepted or rejected using multiple linear regression analysis. The test used 3wqato test the research instrument is a validity test and a reliability test. Hypothesis testing using the t test (partial), F test (simultaneous), multiple linear regression analysis, correlation coefficients and determination with the help of SPSS 21 Software for Windows.

From the results of the multiple regression test the constant value of 13.465 states that if there is an increase in the variable Work Experience (X1) and Work Motivation (X2) the value is 0, then the Work Productivity (Y) value is 13,465. Correlation coefficient value 0.861 means that there is a very strong relationship, the value of determination is 74.2%. Work Experience Variable partially influences and significantly affects Work Productivity with a tcount of 6.442> t table 1.664, this shows that Ho is rejected and H1 is accepted. Work Motivation Variable is partially influential and significant, this is indicated by the value of tcount 5.890> t table 1.664 with a significant value of 0.000 <0.05. This shows that Ho is rejected and H2 is accepted, meaning that the Work Motivation variable partially influences Work Productivity. So, if the value of the variable Work Motivation rises, Work Productivity will increase. Work Experience and Work Motivation simultaneously have a significant effect on Work Productivity. Based on the statistical test F (simultaneous), it can be seen that the value of Fcount 110.483> Ftable 3.09 and a significant value of 0.000 <0.05, it can be concluded that Ho is rejected and H3 is accepted, this means that Work Experience and Work Motivation simultaneously have a significant effect on Work productivity.
Pengaruh Collective Bargaining Agreement dan Perceived Organizational Support terhadap Kinerja Karyawan yang dimoderasi Komitmen Organisasi di PT Internusa Caterindo selama Masa Pandemi Covid-19
Authors: Lukiyana Lukiyana , Yusuf Muhammad
Published: August 2022

This study aims to determine the effect of Collective Bargaining Agreement (CBA) and Perceived Organizational Support (POS) on Employee Performance during the Covid-19 pandemic moderated by Organizational Commitment at PT Internusa Caterindo. The population in this study were employees of PT Internusa Caterindo in the Delta Silicon area of Cikarang. The research sample was 100 employees of PT Internusa Caterindo. The type of data created is primary data using a questionnaire that is filled in directly by one hundred respondents and then processes the data using Partial Least Square (PLS). Statistical results from research data show that the collective bargaining agreement has a positive and insignificant effect, perceived organizational support can have a positive and significant effect, organizational commitment has a positive and significant effect, the moderating effect of organizational commitment has not been able to strengthen the influence of the collective bargaining agreement and perceived organizational support on employee performance.
The optimization of abnormal uterine bleeding treatment in women with chronic psychogenic stress
Authors: Fedosiuk K.V.
Published: August 2022

The objective: to assess the effectiveness of the complex optimized treatment approach to abnormal uterine bleeding (AUB) in women with chronic psychogenic stress on the quality of life.Materials and methods. We examined 100 women of reproductive age with AUB and chronic psychogenic stress, 50 patients of them consisted the I group and received the optimized treatment, and 50 persons (II group) received the standard AUB treatment. 30 women without AUB and chronic stress were included in the control group. The examination of all persons included: anamnesis, clinical and gynecological examinations, ultrasound examination, general blood test, blood ferritin, vitamin D in serum blood. The quality of life was determined according to the 36-Item Short Form Health Survey before treatment and after three months. The standard approach included diagnostic and therapeutic measures according to the recommendations of Order N 353 dated 13.04.2016 of the Ministry of Health of Ukraine. The optimized treatment additionally included recommendations for lifestyle changes, melatonin, the use of vitamin D depending on its level, the medicament correction of iron deficiency without anemia.Results. The results of the questionnaire 36-Item Survey scales indicate that in patients with AUB and chronic psychogenic stress there is a decrease in the scales relative to the values of healthy women, especially in psychological component. In the persons of the II group there was no significant dynamics of the scales “Bodily pain” and “Physical role functioning” relative to the indicators before treatment, while the scales “Physical function” (p<0,001) and “General health perceptions” (p=0.01) increased significantly. The optimized treatment lead to a significant increase in all physical component scales compared till normal indices. In patients of the II group the indicators of psychological scales after treatment were significantly lower than the average values of healthy women. Thus, the value of the scale “Mental Health” was lower by 14,34% relative to the control group (p=0,18), “Emotional role functioning” – 18,38% (p=0,007), “Social role functioning” – 15,46% (p=0,003), “Vitality” – 23,27% (p=0,005). In the women of the I group there was a significant increase in the indicators of the psychological scales, which after treatment reached the values of healthy women.Conclusions. In women with AUB and chronic psychogenic stress, there is an insufficient positive dynamics in improving the quality of life after the standard treatment, especially the scales of the psychological component. The optimized treatment approach leads to the improvement of all parameters of quality of life of the patients.
DERIVING CUSTOMERS PREFERENCES FOR HOTELS FROM UNSTRUCTURED DATA
Authors:   Universitas Airlangga, Faculty of Vocational Studies, Surabaya, Indonesia, DINA Nasa Zata , JUNIARTA Nyoman ,   Université de Lorraine, Faculty of IAEM, Nancy, France
Published: August 2022

Hotel management uses customers' online reviews to uncover the most essential criteria for hotel selection to support sustainable tourism development and strengthen their marketing strategy as well as decision-making. This study implemented the Multi-Criteria Decision-Making (MCDM) to identify customers’ satisfaction and preferences. Data were collected from online reviews on eight hotels in Ubud, Bali Islands, submitted on TripAdvisor. The findings demonstrate that customers have varying levels of satisfaction when it comes to dissimilar preferences. Five major criteria influence their choices, namely price, cleanliness, location, facility, and food. The result of this study will help hotel management to set priority instructions for improving the corresponding hotel features.
The Political Ramifications of Corruption Experience for Political Trust and Pro-Leadership Voting: Evidence from Russia
Authors: Reisinger William M. , Zaloznaya Marina , Ma Haofeng
Published: August 2022

How do citizens’ experiences of corruption affect their political trust and voting behavior? By analyzing a nationally representative survey of Russian citizens conducted a few months after the 2018 presidential election, we find that citizens who engaged in street-level bureaucratic corruption in the preceding two years assess the national leadership as more corrupt and express lower trust in them. This association between corruption engagement and a worsening of people’s views remains even when citizens gained benefits by providing officials with an incentive. We also show that higher perceptions of elite corruption and lower trust in the political leadership are important factors in reducing pro-Kremlin voting. Our findings indicate that even in an authoritarian country citizens’ negative experiences with bureaucracy reduce political support for the national political regime.
PECULIAR FEATURES OF NEGATIVE IMPACT ON LONG-TERM DURATION IN UKRAINE AND IN FOREIGN COUNTRIES: COMPARATIVE LEGAL ANALYSIS
Authors: Chopko Khrystyna
Published: August 2022

The article considers the legal frameworks for the rationing of negative impacts on the state of the environment in accordance with the laws of Ukraine and foreign countries. The author pays special attention to the analysis of the existing standards system of negative impact on the state of the environment in Ukraine. The legal nature of ecological standards is clarified, namely: maximum permissible emissions of polluting chemicals into the environment, maximum allowable discharges of polluting chemicals into the environment, levels of permissible harmful effects of physical factors on the environment as well as levels of permissible harmful effects of biological factors on the natural environment. Certain shortcomings of the list of ecological standards enshrined in the laws of Ukraine are identified, namely the absence of such environmental safety standards as environmental quality criteria («hygienic normative»). In the article, the author investigates the indicators that serve as the basis of environmental regulation in Ukraine, such as: medical (maximum level of threat to human health, its genetic program), technological (the economical capacity to ensure certain limits of impact on humans and the environment) and scientific-technical (the ability of scientific and technical means to control compliance with the limits of influence according to all its parameters). The main aspects and features of environmental regulation carried out in foreign countries are clarified and a comparative analysis with environmental standards provided by national legislation is made. The author proves that the system of existing environmental frameworks in Ukraine is still underdeveloped and does not cover all the aspects of human safety in the natural environment.
THE RIGHT TO BE FORGOTTEN: ESTABLISHMENT AND DEVELOPMENT
Authors: Sadovska Diana
Published: August 2022

The article deals with the main stages of development of the right to be forgotten at the international level. The order of formation and legal regulation of the right to be forgotten is investigated. Special attention is paid to expanding human rights in a world undergoing digital transformation, in particular for the protection of privacy on the Internet. A general conclusion is made concerning the right to be forgotten and its role in solving the problem of protecting the rights of individuals from disseminating incomplete and irrelevant information about them on the digital network. Three separate categories of the right to be forgotten are analyzed: deleting publication by the owner; deleting re-posted content by the content-owner; and deleting publications made by one user about another user. The need to improve the legal regulation of the right to be forgotten is defined. The importance of taking into account the relationship between the right to be forgotten and other human rights, in particular the right to freedom of expression and access to information, is proved. The necessity of developing unified rules of data deletion as well as the insufficiency of regulation of just a part of digital space for ensuring reliable protection of the privacy of users is substantiated. The emphasis is made on the mostly positive public perception of the right to be forgotten and the large number of requests for removal since the launch of the online form in 2014. The validity of some scholars' concerns about possible abuses in deleting information is substantiated. The complexity of the practical realization of the right to oblivion due to the variability of the technological world and the resistance of IT giants is established. It is substantiated that due to the technical impossibility of complete removal of inaccurate information, it is necessary to pay attention not only to legal protection mechanisms, but also to increase the legal awareness of Internet users.
THE CONCEPT, ESSENCE AND SIGNIFICANCE OF INCENTIVES, APPLICABLE TO THE JUVENILES SENTENCED TO IMPRISONMENT
Authors: Burdina Tetiana
Published: August 2022

The article is devoted to the study of various approaches to understanding the concept, content, essence, purpose and significance of incentives in legal science. Therefore, in studying this legal category, which is interdisciplinary and complex, the author was based on the scientific positions of both Soviet and modern Ukrainian researchers, established in the general theory of law and such legal sciences as labor, administrative, criminal and criminal executive law. Consequently, the article highlights that the various scholars view incentives as an act of approval and recognition of merit; as a peculiar form of positive assessment and reward of useful (honest, lawful) behavior associated with excessive performance of one's duties; as a means of stimulating law-abiding behavior of convicts, which serves the purpose of their further correction and resocialization. The latter interpretation is quite broad and unanimously substantiated in the science of criminal executive law. Thus, in general, the stimulating value of incentives is emphasized, in particular, by such scholars as the representatives of the theory of law V. M. Baranov, O. V. Malko and O. O. Barabash, Soviet theorists of labor law O. I. Zaretska and S. S. Karinskyyi as well as Soviet and Ukrainian researcher of labor law O. T. Barabash, representatives of Soviet science of correctional labor law F. R. Sundurov, I. A. Tarkhanov, Y. M. Tkachevskyyi as well as Ukrainian theorist of criminal executive law O. M. Dzhuzha. Moreover, on the influence by the application the measures of incentives on the stimulation of law-abiding behavior of convicts and, consequently, their further correction and resocialization emphasize their attention such scholars in the field of criminal executive law, as Soviet researchers M. A. Yefimov, V. P. Artamonov, as well as Ukrainian scholars O. G. Kolb, P. V. Khryapinskyyi, N. B. Khlystova, N. V. Kolomiyets, Z. V. Yaremko. The author also adheres to this scientific position in understanding the nature, purpose and significance of the measures of incentives and believes that they are primarily intended to stimulate further law-abiding behavior of persons sentenced to imprisonment, including juveniles, with the purpose to correct and resocialize them, as well as prevention of further commission of new offenses both by the convicts themselves, to whom the measure of incentives was applied, and by other persons.
Employee motivation as a remedy to organisation sustainability among SMEs in Lagos State, Nigeria
Authors: Ademola Ishola, S. , Oyerinde Olugbenga O.
Published: August 2022

The challenges of the organisation sustainability appear to be enormous and can overwhelm Small and Medium Enterprises thereby declining their capacities of contributing to the gross domestic product and decrease the rate of unemployment. The failure to demonstrate required employee motivation which in turn affect many SMEs employee performance seem to be the major challenges which SMEs are facing in today’s dynamic business environment. This study, therefore, examines the employee motivation, employee performance and organisation sustainability among SMEs in Lagos state, Nigeria. 100 copies of the questionnaire were distributed, 94 were returned and found usable. Frequency distribution (percentage analysis) was used to analyse data. The findings revealed that employee motivation had significant effect on organisation sustainability. Also, the combined effect of employee motivation and employee performance have positive and significant effect on organisation sustainability. The socio-demography variables (sex, marital status, age, years of experience and educational qualification) have positive relationship with the variables under investigation. The study concludes that employee motivation and employee performance have significant effect on organisation sustainability. Thus, it was recommended that owners/managers of SMEs should be motivating their employees from time to time which can spur the employee performance and result to organisation sustainability among Small and Medium Enterprises in Lagos State, Nigeria.
Impact of capital market performance on economic growth in Nigeria: a systematic review
Authors: Bello Umar
Published: August 2022

A systematic review of Capital market research from 2012 to 2021 identifying relevant features and characteristics of these studies and thereby proffering suggestions for future research. The study used the Systematic Quantitative Assessment Technique (SQAT), a methodology for the identification and selection of high-quality peer-reviewed journal articles, all selected journal articles studied the impact of the capital market on economic growth. A total of 51 Journal articles; were used for the review. Analysis revealed that many of the studies were conducted in Nigeria, while some articles were from different continents, but were significantly empirical. The focus of many Capital market article themes was studying the Capital market and how it influences economic growth. A limitation was the use of high-quality academic database that could not provide enough articles for the review; hence, the use of Google Scholar open search for the selection of relevant articles. The study concluded that capital market performance influenced economic growth even though with disparity among different nations due to the difference in the level of development of capital markets across the globe. It was recommended that research on capital markets requires more attention due to the clear nexus between the capital market performance and economic growth.
The effects of pension scheme on the socio-economic development of the pensioner, a case of North Central, Plateau State, Nigeria
Authors: Daniel Adamu
Published: August 2022

The purpose of this is to discover the effect between pension scheme and socio-economic development in North Central Part of Nigeria. How does pension Programmes affect the livelihood, prosperity, GDP and Infrastructural development of the pensioner. The design of this study was Adopted a case (study which is a research method were a researcher focuses on a specific area whose results are inference to represent the entire populations. The instruments of data collection was printed questions given to group of retirees and some civil servants to fill with the aim of collecting data and was analyzed using simple  using  correlation as well as analysis of variance (ANOVA) the result of this research shows that the value is less than the significant level at 5%, we can therefore reject the null hypothesis and conclude that pension scheme has significant effect on socio- economic development of pensioners in North central part of Nigeria. On the other hand ,for second research question, we can discovered  that the value is less that the significance level (0.05). we again reject the null hypothesis and conclude that regular payments of retirees benefits has a significant impact on the livelihood of  pensioner  in line with the priory expectation that Sets the research in  motion again on the probit regression results. We can see that indeed the level of payment of retirees pension is positively Related to their overall wellbeing. However, the impact of payment so far affect their livelihood insignificantly. Hence, the relevant authorities should check and Address The issues relating to  payments of benefits such as  late payment ,as it has adverse effects  on the socio economic (well-being) of pensioners.
The spatiotemporal interpretation of wave function may solve the mystery of quantum entanglement
Authors: Deng Xiao-han
Published: July 2022

In this paper, the wave function is interpreted as space-time: under any representation, the real part of the wave function represents space and the imaginary part represents time. A wave function represents the quantum entanglement (correlation) between time and space. The unitary evolution process is the mutual transformation of space-time. The imaginary time indicates that it can entangle with space in a non localized way and dominate the integrity (unification) of a quantum, which is the essence of quantum entanglement.
Acquired left handedness in a patient with chronic right motor neglect
Authors: Priftis Konstantinos , Piccione Francesco , Dipersia Maria Lucia , Finco Nicoletta , Gottardello Federica , Masiero Stefano
Published: July 2022

Right motor neglect following left hemisphere damage, in right-handed patients, is very rare and can cause acquired left-handedness. Although right motor neglect has been mentioned in group studies (Laplane & Degos, 1983), there are only two detailed case reports in the literature (De La Sayette et al., 1992; Manabe et al. 1999). Nonetheless, in both reports, right motor neglect disappeared some months following lesion onset. Furthermore, no specific details were reported on the transformation of right-handedness into left-handedness, in these patients, following lesion onset. We reported on WY a very rare case of chronic right motor neglect still present eight years after lesion diagnosis (i.e., a brain tumor). WY was neither affected by motor disorders in his right upper limb nor by any form of right neglect, although there were some very mild signs of sensory extinction. Nonetheless, WY, who before lesion diagnosis was strongly right-handed, he has now become left-handed/ambidextrous for most of his everyday life activities. Strangely enough, he still declares that his “good and strong” hand remains the right one!
Differential expression of RAB3IP in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of RAB3IP, encoding RAB3A-interacting protein, in primary fibroblasts of patients with sporadic ALS (SALS). RAB3IP transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Differential expression of SCNN1A in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding sodium channel epithelial 1 alpha subunit, SCNN1A, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. SCNN1A mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of SCNN1A in primary tumors of the breast was correlated with distant metastasis-free survival in patients with luminal B subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. SCNN1A may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of RAB11FIP3 in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding RAB11 family-interacting protein 3, RAB11FIP3, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. RAB11FIP3 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of RAB11FIP3 in primary tumors of the breast was correlated with distant metastasis-free survival in patients with normal-like subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. RAB11FIP3 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of ZNF208 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of ZNF208, encoding zinc finger protein 208, in primary fibroblasts of patients with sporadic ALS (SALS). ZNF208 transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Exploring Parent-Child Dyadic Networks to Design a Smartphone-based Mindfulness Intervention for Underserved Families
Authors: McGowan Amanda L. , Lydon-Staley David M.
Published: July 2022

Parents from socioeconomically disadvantaged and minoritized backgrounds disproportionately experience higher rates of daily negative mood and lower levels of physical activity, negatively impacting health outcomes across the lifespan. Scalable, evidence-based interventions to promote family wellbeing and that fit into the busy lives of parents juggling many responsibilities remain beyond reach, especially for families from minoritized groups experiencing the greatest barriers to health. Mindfulness holds promise for addressing these disparities in access to evidence-based behavioral health interventions because it can be engaged upon at any given moment, can be delivered using smartphones, has higher rates of program completion relative to other evidence-based treatments, and has high rates of being integrated into daily life following study completion. In this study, we used smartphone experience-sampling and accelerometry to respectively measure mood and physical activity in 31 parent-child dyads. Parents reported negative mood and stress 10 times per day across 14 days for themselves and their child (3-8 years old). We used Group Iterative Multiple Model Estimation to construct networks describing associations among negative mood, stress, and physical activity for each parent and child dyad. Our findings suggest that we can use a complex systems approach to model the associations among mood, stress, and physical activity in parents and children in daily life. We discuss opportunities for using these parent-child dyad networks to inform the design of parent focused smartphone-based mindfulness interventions to support healthy parent-child interactions and reduce health disparities.
You Never Get a Chance to Undo a Negative First Impression: Social Anxiety is Associated with Impaired Positive Updating of Social Information
Authors: Zabag Reut , Azoulay Roy , Rinck Mike , Becker Eni Sabine , Levy-Gigi Einat , Gilboa-Schechtman Eva
Published: August 2022

In an ever-changing social world, learning and updating beliefs about others are essential for smooth interpersonal functioning. Social anxiety is a common and burdensome condition involving difficulties in interpersonal functioning. However, the processes governing the learning and updating of beliefs regarding others, processes crucial for these interactions, are poorly understood. To address this gap, we used a novel modification of a reversal-learning task. The task consisted of two phases. Participants first learned that interactions with some individuals were associated with negative outcomes and other individuals with positive outcomes. Later, these associations were updated. Hence, negative individuals became positive and vice-versa. Study 1 (n=87; undergraduate students) revealed that social anxiety was not associated with biased learning of positive or negative information about others. However, social anxiety was associated with a deficit in the positive updating of existing negative beliefs. Study 2 (n=248; Mturk) replicated these findings in a representative and demographically diverse sample, controlling for depression severity and age. This research suggests that social anxiety-related difficulty in positive updating of social information may contribute to the impairment in interpersonal functioning.
A qualitative analysis of free-text responses exploring smokers’ arguments against vaping: implications for e-cigarette messaging
Authors: Carlisle Victoria , Maynard Olivia M
Published: August 2022

Background: Despite considerable evidence that vaping is a safer alternative to smoking, there is a common misperception among smokers that electronic cigarettes are as or more harmful than cigarettes. Messaging which highlights the benefits of e-cigarettes to current smokers, while also discouraging use among non-smokers may be effective at changing these beliefs. Method: In this online survey, 452 UK smokers who do not vape responded to messages about quitting smoking. We used thematic analysis to qualitatively analyse their free-text responses to the messages about vaping. Findings: There were 102 qualitative responses, from 87 participants to the e-cigarette messages and the sentiment of these was largely negative. We developed three themes which encapsulate key arguments smokers made against using e-cigarettes: 1) The science isn’t convincing, 2) Vaping is harmful and 3) Vapes aren’t helpful with quitting. Participants were worried about the lack of scientific evidence and the conflicting evidence they had received. They were concerned about the long-term risks of vaping and nicotine. Conclusions: While some of the arguments we identified are based on personal preferences, others were based on uncertain risk perceptions (e.g., the harm caused by nicotine or the long-term risks of vaping). Here we examine these risk perceptions in the context of existing theory and evidence on risk and provide recommendations for future communications to smokers who are skeptical of e-cigarettes. Together, this research builds a deeper understanding of smokers’ key anti-vaping arguments and provides a framework for developing e-cigarette messages which can address these fundamental concerns.
Peran Perempuan Sebagai Kepala Keluarga
Authors: fatichatan
Published: August 2022

Tulisan ini bertujuan untuk menganalisis peran perempuan sebagai kepala keluarga ditinjau dari perspektif Qira’ah Mubadalah. Jenis penelitian ini adalah penelitian pustaka dengan menggunakan metode kualitatif dan analisis gender, yang menghasilkan data secara deskriptif analitis. Hasil penelitian menunjukan bahwa dalam perspektif Qira’ah Mubadalah kebutuhan nafkah keluarga pada prinsipnya adalah tanggung jawab suami dan istri. Masing-masing dapat berbagi peran secara fleksibel, dan saling bekerja sama dalam mengemban tugas dan amanah rumah tangga.
Makrofauna Tanah Sebagai Bioindikator pada Areal Perkebunan yang diberi Limbah Cair Pabrik Kelapa Sawit Sebagai Pupuk
Authors: John Arlen Hanel
Published: August 2022

Research on Soil Macrofauna as Bioindicator in Plantation Areas Given Palm Oil Mill Liquid Waste as Fertilizer was conducted in 2021. Samples were taken in Long Bed, Flat Bed, and Control areas using Purposive Sampling and Squares and Hand Sorting methods. Each location is determined by 9 sampling points. Soil macrofauna samples were identified in the USU FMIPA Ecology laboratory. From the results of the study, there were 3 soil macrofauna phyla, namely the Annelida phylum, which consisted of 1 class, 1 order, 2 families, and 2 species. Phylum Arthropoda consists of 5 classes, 10 orders, 16 families, and 27 species. Phylum Mollusca consists of 1 class, 1 order, 1 family, and 1 species. The highest population density (K) was obtained from the species Macrotermes gilvus, which was 81.10 individuals/m2 in the Control area, followed by Ponthoscolex corethrurus at 78.81 individuals/m2 in the Flat Bed area. The highest relative density (KR) was found in the species Macrotermes gilvus, which was 49.1% in the control area, followed by Ponthoscolex corethrurus at 46.84% in the Long Bed area. The highest frequency of presence (FK) was found in the Ponthoscolex corethrurus species, which was 100% in the Control and Flat Bed areas, and 88.88% in the Long Bed areas. Species that can live and reproduce well as bioindicators are Ponthoscolex corethrurus in the Long Bed area, followed by the Flat Bed and Control areas. The highest diversity index value was found in the Flat Bed area, which was 3,831 with the criteria for diversity being high, the distribution of the number of individuals for each species was high, the community stability was good and the soil community had not been polluted, while the Equitabilitas value was 1,258 with the criteria for high uniformity, stable community. The application of palm oil mill effluent as fertilizer to the plantation area can increase the life of the soil macrofauna, and the physical-chemical properties of the soil.
Daya Dukung Kawasan dan Daya Dukung Rill pada Ekowisata Sungai Mudal Banyunganti, Jatimulyo, Kulon Progo, DIY
Authors: Ayumadany Maulidya Anggun , Prasetya Johan Danu , Gomareuzzaman Muammar
Published: August 2022

Mudal River ecotourism is located in the Menoreh Hills which is a geological protected area and the area around the springs in the RTRW of Kulon Progo Regency. Since 2015 the Mudal River has been used as a tourist spot in the ecotourism category. These ecotourism activities have increased significantly from year to year when viewed from secondary visitor data for 2015-2018. The study was conducted to determine the value of the carrying capacity of the area and the real carrying capacity which is an effort to prevent damage that occurs in ecotourism areas in protected areas. The method used in this research is a survey and field method. Data on the parameters of carrying capacity and area and real carrying capacity were obtained from the survey and field activities. Based on the results and data processing carried out, it was found that the carrying capacity of the area (DDK) was 701 people/day (consisting of DDK utilization of playing water 637 people/day, DDK utilization of sitting relaxed 57 people/day, and DDK utilization of camping 7 people/day). Meanwhile, the real carrying capacity value is 1151 people/day. The two results obtained are still far above the existing visitors to the Mudal River Ecotourism so the carrying capacity of ecotourism activities is still in accordance with the value of the carrying capacity of the area and the real carrying capacity.
Studi Kadar Fosfat (Total, Polifosfat dan Ortofosfat) pada Daerah Aliran Sungai Lamat Kecamatan Muntilan
Authors: Jati Marius Agung Sasmita
Published: August 2022

Studies on phosphate levels (total, polyphosphate, and orthophosphate) have been carried out in the Lamat Muntilan watershed. A detergent is an approach to the amount of waste disposal of various types of phosphate in the Lamat river. High levels of phosphorus cause eutrophication, which can cause various human health problems. This study aims to determine the levels (total, polyphosphate, and orthophosphate) and compared rain and dry season with water quality standards that have been agreed upon nationally as well as theoretical studies on eutrophication pollution. This research uses the UV-Vis Spectrophotometer method by utilizing the interaction of ammonium tartrate and potassium antimonyl tartrate on orthophosphate ions to form phosphomolybdic acid which is then reduced by ascorbic acid to a modern blue color which is proportional to the number of orthophosphate ions. This modern blue color is measured at a wavelength of 880 nm. The result data showed that the average total phosphate levels of river water of 0.240 ppm in the rainy season and 0.204 ppm in the dry season, for polyphosphates were found at 0.032 ppm in the rainy season and 0.064 ppm in the dry season, while orthophosphate 0.051 ppm in the rainy season and 0.101 ppm in the dry season. In the dry and rainy seasons, there were specific differences between them. This level surpassed Peraturan Pemerintah Republik Indonesia Nomor 82 Tahun 2001 about concerning Management of Water Quality and Control of Pollution Water, was not suitable for consumption directly or indirectly specifically for human needs, but if it was used for animals and plants it is still feasible. The level of all phosphate species triggered the formation of eutrophication.