bluuebunny/crossref_metadata_2025 huggingface dataset:
The role and significance of audit sampling in the modern enterprise
Authors: Krunić Nikola , Stojmenović Gordana , Kukolj Saša
Published: April 2023

Auditing is an activity that is present in today's world at every step and in every branch of the economy. When we mean the audit of financial operations, it means that the audit is carried out on the total financial operations of the entity in a certain period of time or includes the audit of a specific economic sector. The audit of financial operations is carried out with the aim of determining the actual financial condition of the entity in a certain period. It is also carried out in situations where there is suspicion of misuse of financial documents or in other situations when management authorities require it. It differs from other types of audit, not only because the subject of the audit is financial statements, but it is necessary that its auditors possess professional and ethical qualities. The audit of financial statements includes the collection and evaluation of evidence in a systematic way, which creates a basis for validating financial statements and checking their compliance with international accounting standards and international financial reporting standards.
Evaluation of VAT efficiency in Benelux countries
Authors: Inđić Milica , Mirović Vera , Kalaš Branimir , Đaković Miloš
Published: April 2023

The relevance of value added tax is reflected in the generation of a significant amount of revenue and the suppression of tax evasion. The purpose of the research is aimed at assessing collected revenues and measuring the efficiency of VAT revenue collection in the Benelux countries (Belgium, the Netherlands and Luxembourg) for the period 2011-2020. years. Empirical research results indicate that the average VAT efficiency was 59.84% in the observed countries. where the highest degree of efficiency was recorded in Luxembourg, and the lowest value in Belgium. Panel regression results show that economic growth, final consumption, government expenditures and VAT revenues have a positive effect on VAT efficiency in the observed countries. At the same time, variables such as unemployment and inflation, as well as the standard VAT rate, have a negative effect on the efficiency of VAT revenue. The obtained empirical findings can be of help to economic policy makers in the analyzed countries when profiling and adjusting tax policy from the point of view of value added tax.
Political economy of money
Authors: Ristić Kristijan , Živković Aleksandar , Jemović Mirjana
Published: April 2023

The former polarization of financial theorists regarding the importance of money is characteristic more than a decade confrontation monetarist and Keynesians, theirs long - term debate and opposition thesis " money it's not important " and " just is Money important ", The last two decades of the twentieth century are characteristic of the official common house thesis that " money it is important " The justification for the need for a theoretical analysis in this work and today is found in the fact that contemporary macroeconomic theory recognizes the end of radical anti-Keynesianism and at the same time the end of the intellectual monopoly of the dominant neoliberal doctrine that logically relies on and/or emerges from it, namely monetarism and all later theoretical derivatives. On the other hand, the goal of this work is not to reach the possibility of formulating new theoretical propositions, but rather to review the conflicting positions of representatives of different doctrines in financial theory to see current problems and controversies, and possibly still unresolved dilemmas, both in financial theory and in the management of monetary policy. and fiscal policies. in the world and here too.
Impact of the pandemic COVID - 19 on the digitalization of the banking sector of Serbia
Authors: Božović Jelena , Božović Ivan
Published: April 2023

This paper examines the consequences of COVID-19 on the digitalization of the banking sector, in order to identify the challenges and opportunities of the banking sector in Serbia. The research consists of two parts. The first part uses statistical data from regulatory and supervisory bodies, and the second part refers to field research, which is based on a survey. Data processing was created using IBM SPSS Statistics software. Survey questionnaires were collected in the period from January to May 2022. The answers of 174 respondents, bank clients, were accepted for analysis. The questionnaire was compiled using a five-point Likert scale. This sample may not be entirely representative, but in any case it is sufficiently informative, as it is possible to draw a conclusion about the contribution of each variable to the development of digital banking. To analyze the relationship between the metric variable and several independent variables, we use multiple or multiple regression. Our assessments reveal the impact of digital products and services on the development of digital banking. In the research, specific goals should be determined, specifically what percentage of respondents are familiar with digital banking services. Also, further analysis should verify the statement that the proportion of respondents who have a negative attitude towards digital banking is less than 45%. In this research, regression analysis was used, as part of the analysis used to form the digital maturity of clients in Serbia. A two-factor analysis was used to research the preferred types of banking products and services. Data analysis using SPSS version 20 for Windows shows that: There is a positive and significant impact of digital banking products on bank customer satisfaction. Analyzed models for researching client preferences indicate that the bank's managerial approach implies real knowledge and monitoring of the wishes and preferences of its clients, as well as adequate key priorities that managers of the banking industry should provide. The research results show that a digital bank can be a unique answer to all challenges, as well as the most effective tool for retaining and attracting clients.
Skin Cancer Chemoprevention for Solid Organ Transplant Recipients - The Search Continues
Authors:   Massachusetts General Hospital, Kaufman Howard , Patel Vishal ,   GW School of Medicine & Health Sciences, Shalhout Sophia ,   Mass Eye and Ear, Gupta Sameer ,   Mass Eye and Ear, Cohen Sonia ,   Massachusetts General Hospital, Brownell Isaac ,   National Institute of Health, Miller David ,   Massachusetts General Hospital
Published: April 2023

In this Perspectives on the Science piece, we reflect on the impact of the recently published ONTRANS trial.
PREDICTION OF SUSCEPTIBILITY FOR OLD TREES (> 100 YEARS OLD) TO FALL IN BOGOR BOTANICAL GARDEN
Authors: Indresputra Faozan , Zulkarnaen Rizmoon Nurul , Hariri Muhammad Rifqi , Wardani Fitri Fatma , Hutabarat Prima Wahyu Kusuma , Setyanti Dwi , Pratiwi Widya Ayu , Rahmaningtiyas Lutfi
Published: April 2023

Preservation effort to prevent tree collections loss even on aged trees (> 100 years old) is one of important missions in Bogor Botanical Garden since its establishment in 1817. Abiotic factors such as global warming and biotic factors from pests and diseases can threaten the survival of aged tree collections. Their survival is also influenced by plant health’s deterioration as they age. As the BBG has many functions not only for conservation but also for human ecological activities, fallen tree accidents are becoming primary concern to prevent biodiversity loss and people’s lives. We examined 154 trees health to determine a falling probability of 1106 aged trees based on several factors that caused to fall in the past and to make model prediction generated by nine supervised machine learning algorithms. We also classify susceptibility of tree families prone to fall from the highest accuracy of algorithm prediction. Inverse Distance Weighted interpolation method was used to depict zone map of trees prone to fall. The prediction showed that Random Forest model had the highest accuracy and low false negative (FN) value which were important to minimize error calculation on aged trees was not prone to fall but it turns out to be prone to fall. It predicted 885 trees prone to fall which 358 had high probability to fall. Fabaceae, Lauraceae, Moraceae, Meliaceae, Dipterocarpaceae, Sapindaceae, Rubiaceae, Myrtaceae, Araucariaceae, Malvaceae, and Anacardiaceae were tree families that were highly predicted to fall.
POLARIZATION OF LOCAL COMMUNITY PERCEPTION ON SOCIO-CULTURAL DYNAMICS IN ECOTOURISM DEVELOPMENT OF BOPUNJUR, WEST JAVA
Authors: Widodo Gatot , Avenzora Ricky , Malihah Elly , Sunarminto Tutut
Published: April 2023

In addition to providing multiplier economy benefits, the tourism sector also has the potential to cause some latent and massive negative social impacts. For this reason, it is important to map out the orientation of the local community. This study aims to analyse the polarization of local community's perceptions about socio-cultural dynamics in the ecotourism development area. The local community that became the focus of the research consisted of five groups of respondents, namely traditional leaders, religious leaders, educational leaders, community leaders, and tourism actors. This research was conducted in the Bopunjur Ecotourism Area, Bogor Regency, West Java, precisely in seven ecotourism destinations, namely Ciawi, Caringin, Cibogo, Cipayung, Megamendung, Cisarua, and Tugu. This study used an exploratory – phenomenology approach. Data collection on social and cultural dynamics was carried out by distributing questionnaires to the respondents. The research instrument in the form of a questionnaire designed with a closed ended with guidance on one score one indicator scoring system. The results showed that positive social situations namely conducive situations, associations, cooperative situations, and productive collaborations were still more dominant than negative social situations: war, conflict, and dissociation. The polarization of local community on socio-cultural dynamics has a positive direction with a polarization scale that is aligned with each other so that there is a great opportunity to build productive collaboration between stakeholders in this area.
FORMULATING STRATEGIES BASED ON LOCAL COMMUNITY’S PERCEPTIONS FOR CAVE AND BAT ECOTOURISM DEVELOPMENT: A CASE STUDY OF TOGENRA CAVE IN BARRU, SOUTH SULAWESI
Authors: Illa Maulany Risma , Ansharullah Ahmad Syarif , Hamzah Andi Siady , Nasri
Published: April 2023

Togenra cave in Madello Village, Barru Regency (South Sulawesi) is located in the Tonasa Karst Formation, known as one of the largest formations in Asia and is also popular for its unique features and functions. Currently, the local government has not yet established a regulation on the management of the cave, and locals are free to access the cave for calcium and guano mining which can threaten the ecosystem of the cave. Therefore, it is necessary to develop non-consumptive use of the cave, through ecotourism that can provide long-term benefits to the local communities. This study aimed to examine the community’s perceptions toward the cave, bats and conservation; formulate strategies by assessing the potency of the cave and bat species as an ecotourism spot based on the local’s perceptions; and provide recommendations for the local government in supporting both ecotourism and conservation in the area. The study was conducted from August 2020 to February 2021. A set of questionnaires were to 31 respondents living within a radius of 1 km from Togenra cave. Formulation of strategies were done by using combined analyses of Strength, Weakness, Opportunity, Threats and Analysis of Hierarchy Process. Our analyses indicate a growth strategy trend. Several strategies drawn emphasize on improving local’s knowledge and perceptions, active involvement of locals, establishment of local management initiatives and regulations, capacity enhancement, and implementation of a stakeholders’ forum. These findings can become a baseline in planning and developing both bat-cave tourism as well as conservation efforts in the area.
ANATOMICAL INVESTIGATION OF FIVE GENERA THE LEAST-KNOWN TIMBER OF APOCYNACEAE AND THEIR POTENTIAL UTILIZATION
Authors: Marbun Sari Delviana , Astutiputri Vidya Fatimah , Damayanti Ratih , Hadisunarso  , Trisatya Deazy Rachmi , Djarwanto  , Dewi Listya Mustika , Rahmanto Raden Gunawan Hadi , Agustiningrum Dyah Ayu , Pari Rohmah , Sofianto Imran Arra’d , Lisnawati Yunita , Kalima Titi , Suhartana Sona , Setiowati  , Krisdianto  , Wardhani Marfuah , Ismanto Agung , Yuniawati  , Nugroho Agung Wahyu , Utami Sri , Dwianto Wahyu , Fitriasari Widya , Bahanawan Adik , Adi Danang Sudarwako , Augustina Sarah
Published: April 2023

Doubtlessly, wood identification is critically important for a number of sectors, including government organizations, the wooden-based industry, museums, law enforcement, and scientists working in the fields of botany, ecology, forestry, and wood technology. Unfortunately, most wood species listed as “the least-known species” lack essential knowledge or even their anatomical feature and basic properties to promote their usage. This research aimed to investigate the anatomical characteristics and fiber quality of the least-known timber species of Apocynaceae family, which are authentic wood collection from Xylarium Bogoriense, namely  , Ervatamia. sphaerocarpa, E. aurantiaca, Kopsia flavida, Lepiniopsis ternatensis, Plumeria acuminata, P. rubra, and Voacanga foetida.  Wood samples have indistinct growth ring boundaries, diffuse-porous vessels in diagonal and/or radial pattern, vessels in radial multiples of 4 or more cells, simple perforation plate, alternate intervessel pits; distinct borders of vessel-ray pits, similar with those of intervessel pits in size and shape throughout the ray cell, and septate fibers with simple pits to minutely bordered pits which are common in radial and tangential walls. Based on the fiber length and the derived values of fiber dimension, some species are classified into Quality Class II and III, and the rest of them are classified into Quality Class II or III for pulp and paper manufacturing. Based on general characteristics, commonly Apocynaceae can be used as handicrafts raw material. Based on the fiber quality, some species which are classified into Quality Class II, are predicted to have potential as pulp and paper material with medium quality.
The History of Geocryological Study of the Coastal-Shelf Zone of the Laptev and East Siberian Seas in the 1950s–1980s
Authors: Suleimanov Aleksandr Albertovich
Published: April 2023

The historical analysis of the studies carried out during the 1950s-1980s by the staff of the Yakutsk Permafrost Research Station of the Obruchev Permafrost Institute of the USSR Academy of Sciences and since 1962 – organized on its basis by the Permafrost Institute of the Siberian Branch of the USSR Academy of Sciences and aimed at studying the coastal-shelf zone of the Laptev Sea and the East Siberian Sea. The sources for the preparation of the article were the archival materials identified by the author from the funds of the Russian State Archive of Economics and the Archive of the Melnikov Permafrost Institute of SB RAS, as well as scientific literature data. The work carried out made it possible to show the significant activity of researchers in the study of subbottom permafrost. Its drivers were both purely cognitive interest and the needs of the industrial development of high latitudes. In the course of the surveys carried out, data were obtained characterizing the prevalence and thickness of subpermafrost, its temperature regime, composition and other properties.
Lateral and Radial Differentiation of Cryogenic Soils Chemical Composition in the Vilyuy River valley, Central Yakutia
Authors: Vasil'chuk Yurij Kirillovich , Ginzburg Alexander Pavlovich
Published: April 2023

The subject of the study is the soil-geochemical features of cryogenic mid-taiga landscapes of the Vilyuy River valley in its middle course, located near Mahatta and the village of Kysyl-Syr of the Republic of Sakha (Yakutia). Morphological descriptions of soil profiles were compiled. Chemical and analytical laboratory work was carried out in order to establish the values of the physico-chemical parameters of soil horizons - pH, the content of easily soluble salts, the content of organic carbon, granulometric composition, fractional composition of iron. The main aspect of the soil-geochemical properties of the landscapes of the middle Vilyui River is the gross chemical composition of cryogenic soils. The gross contents of chemical elements were determined by X–ray fluorescence using portable X-ray diffraction, after which the geochemical coefficients of radial (profile) and lateral (catenary) differentiation of concentrations of chemical elements R and were calculated. In automorphic soils, most of the chemical elements are removed from their surface organic horizons, and in mineral ones they are concentrated. Ca, Ti, Mn, Fe, Zn and Zr differ by the highest values of the coefficients R (R reaches 20). The radial differentiation is significantly influenced by acidity, organic carbon content and other soil properties, for example, the increased content of Si, Ca, V and Zn (R up to 1,3–3,7) relative to the horizon of soil parent rocks which is associated with the content of Sorghum. In terms of lateral differentiation, most of the studied elements are characterized by accumulation in the upper part of the soil-geochemical catena. The catenae Ca, Mn, Fe, Zn and Y are most widely distributed in soils (LCa = 0.3–1.8; LMn = 0.1–2.0; LFe = 0.6–2.1; LZn = 0.9–2.9 and LY = 0.3–1.4).
Lateral and radial differentiation of cryogenic soils geochemical composition in the Khanovei scientific and educational field site, Bolshezemel'skaya tundra
Authors: Vasil'chuk Yurij Kirillovich , Ginzburg Alexander Pavlovich
Published: April 2023

The subject of the study was the soil and geochemical features of southern tundra cryogenic landscapes on the Khanovei educational and scientific field site located nearby the eponymous settlement in the Vorkuta district, Komi Republic. Morphology of soil profiles were described according to the modern Russian soil classification system. Chemical analytical sample treatment was done to evaluate such physical and chemical parameters of soil horizons as the pH rate, water-soluble salts content, organic carbon content, soil texture, iron fractional composition. The main point among soil and geochemical features of the Khanovei field site was gross chemical composition of cryogenic soils. Gross concentrations of chemicals were measured with the X-ray fluorescence method by portable X-ray Fluorescence Analyzer and then geochemical ratios of radial (profile) and lateral (catenar) differentiation of chemical elements – R and L. Largest R ratio meanings in soil profiles were in gleyic horizons including above-permafrost. Peat horizons without traces of soil mineral fraction were depleted with the most of elements (R = 0,1–0,3) and mineral horizons of soils were differed by increased RFe, RMn etc. The lower part of the catena with soils of mostly sandy texture was depleted by the main part of elements (Ti, Zn, Zr etc.) and predominantly loamy-textured soils in the upper part accumulate these elements and form increased L ratio meanings.
Gas-saturated frozen rocks as an object of geocryology study
Authors: Khimenkov Aleksandr Nikolaevich , Koshurnikov Andrei Viktorovich , Dernova Elena Olegovna
Published: April 2023

The subject of the study of the proposed article is the gas component of the cryolithozone. If the solid and liquid phases of frozen rocks have been studied sufficiently deeply and systematically, then the gas component has been studied weakly and fragmentally. The object of the study is gas-saturated frozen soils, their spatial distribution and properties. Studies of recent decades have shown that the gas component plays a significant role in the structure and properties of frozen rocks. The author examines in detail such aspects of the topic as the effect of gas on the physical and mechanical properties of both thawed and frozen soils. Special attention is paid to the overlap of capillaries in the soil with gas, an increase in pore pressure, a weakening of soil consolidation and connections between soil particles. This, in turn, is expressed in a decrease in strength and density while increasing compressibility and porosity.      The novelty of the study lies in the fact that for the first time a comparative analysis of data on the content of the gas component of the pressure in it and the processes occurring in frozen rocks was carried out. A special contribution of the author to the study of the topic is that the influence of free gas on their physical and mechanical properties is shown. The relevance of the topic under consideration is due to the need to study the patterns of deformation of frozen rocks depending on the degree of gas saturation. The article analyzes the state of the regulatory framework that takes into account the influence of gases on strength and deformative properties. Their almost complete absence was recorded. The importance of taking into account the possible increased pressure in gas-saturated frozen rocks in the development of research methods and regulatory documents for their use in engineering-geological and design work is shown. The materials considered indicate that gas-saturated frozen soils are a significant and important part of the cryolithozone and their study should be carried out within the framework of an independent section of geocryology.
Challenges of Herpetic Eye Infection
Authors: Vassileva Petja , Kirilova Yordanka
Published: April 2023

Human herpes infections are a major cause of morbidity worldwide. Herpes Simplex Virus (HSV) and Varicella Zoster Virus (VZV) are frequent causes of ocular pathology. Ocular herpes is a recurrent disease, and its complications may lead to blindness. Herpetic viral infection is characterized by its ability to remain latent in the nervous system. Reactivation from the ophthalmic branch of the trigeminal ganglion may lead to recurrent attacks.
Ocular herpes is a disastrous disease causing suffering and anxiety to millions of people, and also represents important economic burden. Recently the incidence of varicella zoster virus (VZV) is increasing for unknown reasons. Published data demonstrate also that more that 50% of patients with ocular and systemic manifestation of VZV are younger than 60 years and immunocompetent. We analyze retrospectively 160 consecutive patients with ocular herpes treated at our referral specialized eye hospital, and proposed original approach to different scenarios of disease development.
On ICP-MS Determination of Uranium in Drinking, Ground and Mineral Waters
Authors: Georgiev Valentin , Dakova Ivanka , Karadjova Irina
Published: April 2023

A method for the determination of uranium in surface and ground water samples is developed and validated. The method is based on ICP-MS measurement under optimized instrumental parameters using Re as an internal standard. Model solutions containing major cations in natural waters such as Na, K, Ca, Mg are prepared and used to study the observed matrix interferences on U signal in ICP-MS measurements. Routinely used internal standards La, Tl for U ICP-MS measurement in natural waters are compared to newly proposed internal standard Re. Results obtained showed more efficient interference correction and better reproducibility in the presence of Re applied at concentration level of 10 μg L−1 for internal standard calibration. Analytical procedure developed is characterized by determination limit of 0.04 μL−1 and relative standard deviation in the range 4–6% for the U concentration range from 0.04 to 50 μL−1. The method is validated through the analysis of parallel water samples by using proposed method, by using standard UV-VIS method (arsenazo III), and by analyzing a certified reference material.
Influence of Elicitation on Glaucium flavum Cultures in in Vitro Conditions
Authors: Doycheva Iva , Philipov Stefan , Stanilova Marina
Published: April 2023

Glaucium flavum Crantz is a medicinal plant species which contains high variety of isoquinoline alkaloids, the main of which is the alkaloid glaucine, possessing antitussive activity. In vitro cultivation was investigated as an alternative and sustainable approach for plant cultivation of this species which is characterized by decreasing distribution. The biotechnological production of secondary metabolites could be improved by the addition of elicitors such as jasmonic acid, methyl jasmonate and yeast extract to the artificial medium. The seed germination of G. flavum was over 60% in all examined media supplemented with the abovementioned elicitors. They did not stimulate higher alkaloid production but the plants of some of the investigated in vitro cultures had similar percentage of the crude alkaloid mixture, about 3%, to the native plant population from which they had derived. The quantity of the alkaloids varied but their content in the studied samples remained similar.
Environmental Parameter Analysis during the Extreme Damaging Gale that Hit the East Coast of the Shandong Peninsula
Authors: Wan Fujing , Liu Zhifeng , Mei Chanjuan , Tian Ying
Published: April 2023

In this study, sounding data were used to investigate the environmental parameters of the eastern Shandong coast. June was the month with the most extreme thunderstorm winds, according to the results. Several parameters, which can be referenced in daily forecasts and early warnings, are indicative of extreme thunderstorms and gales. Strong convective storms are often the cause of extreme gales. Usually, there must be moderate to strong vertical wind shear conditions. The wet layer does not need to be excessively thick, but there is a very distinct dry layer with strong entrainment potential in the middle layer.
An Empirical Performance Assessment of Infrared Thermography for Real-time Monitoring of Electrical Systems in the Coco Fibre Industry
Authors: Naveenkumar Pushpalatha , Mohanram Sudha
Published: April 2023

The quality of the electrical network, which includes MV panels, DBs, MCBs, sub-circuits with fuse units, and electrical motors for machine tools, determines production in any sector. Most drive systems employ inductionmotors. System temperature indicates health. Excess temperature is rarely detected due to breakdown. This case study presents real-time data for a leading coir industry from each electrical circuit and motor in several machine tools. Every section is thermographed and compared to the allowed temperature range. Thermographic analysis is non-contact and uses fewer meters and instruments. A harmonic analyzer measures THD using data from the full testing period. Modern energy audits save 10–15% on energy. Suggestions include modest restructuring of electrical network load distribution, little investment in capacitor banks in each section of induction motors, and thorough analysis and corrective measures based on customer needs.
Quercetin Affects Ceramide but not Sphingosine-1-phosphate in ras-transformed 3T3 Fibroblasts
Authors: Momchilova Albena , Pankov Roumen , Krastev Plamen , Markovska Tania , Arabadjiev Borislav , Krastev Nikolai , Vassileva Evgenia , Krastev Dimo , Tonev Dimitar
Published: April 2023

Investigations were carried out on the effect of quercetin on the level of the major sphingolipid metabolites in ras-transformed 3T3 fibroblasts. Quercetin is a polyphenol of a significant biomedical importance, which has been reported to show beneficial effects such as antioxidant, anti-neoplastic, anti-ageing, etc. Sphingolipids are functionally active lipid molecules, which regulate important cellular processes, like proliferation, apoptosis and transmembrane signalling, among others. Despite the numerous investigations devoted to the influence of quercetin on the lipid metabolism of various types of cancer cells, the mechanism of this influence on the major sphingolipid pathways still remains unclear. Our studies showed that sphingomyelin was decreased in ras-transformed 3T3 fibroblasts, whereas ceramide, which is a pro-apoptotic factor, was increased as a result of elevated neutral sphingomyelinase activity. However, the level of sphingosine-1-phosphate, which is related to cell proliferation, was not altered as a result of quercetin treatment, which is an unexpected finding when compared to our previous studies with cancer cells. In addition, the observed changes in the balancing enzyme in the sphingolipid pathway, sphingosine kinase 1, which produces sphingosine-1-phosphate, were not statistically significant in quercetin-treated oncogene-transformed fibroblasts.
The presented data are useful for better understanding of the effect of flavonoids on the regulation of sphingolipid metabolism and could help in the development of complex antitumour therapeutic approaches, involving natural antitumour agents like polyphenols.
Stroke Volume Variation is a Good Predictor of Fluid Responsiveness in Cardiac Surgery Patients with Implanted Intra-aortic Balloon Pump
Authors: Enev Rostislav , Abedinov Fillip , Bakalova Neda , Atanasova Margarita , Chilingirova Nezabravka , Krastev Plamen
Published: April 2023

There is a vast body of evidence in favour of individualising fluid therapy using dynamic hemodynamic indices like stroke volume variation (SVV). Patients with implanted intra-aortic balloon pump (IABP) are excluded from this approach because of pulse contour artifacts caused by the pump. The aim of this work is to test whether SVV can be used for fluid responsiveness prediction in these patients. Patients after cardiac surgery with implanted IABP were included in this study. SVV was measured after placing the IABP on standby mode for one minute. Cardiac output (CO) measurement was obtained via Swan-Ganz catheter before and after a 6 ml/kg fluid challenge. Fluid responsiveness was defined as increase of CO by at least 10%. SVV above 8.5% showed a good correlation with fluid responsiveness. Sensitivity was 95 (95% CI 85 to 100) and specificity 82 (95% CI 72 to 92). SVV had an area under the ROC curve 0.91 (95% CI 0.81 to 1.0) SVV is a good predictor of fluid responsiveness in patients with IABP. SVV should not be excluded as a fluid therapy guide for these patients. Placing the pump on standby for one minute allows obtaining an accurate measurement of this important variable.
Vitamin D Status in Term Newborns and Their Mothers
Authors: Hitrova-Nikolova Stanislava , Koleva Lilia , Georgieva Stefka , Vakrilova Liliya , Petkova Valentina , Dimitrov Milen , Karamisheva Vesela
Published: April 2023

The aim of this study is: 1) To evaluate vitamin D serum levels of fullterm newborns and its association with the maternal levels; 2) To evaluate the diet and the intake of multivitamin supplements of women; 3) To analyze seasonal dependence in serum levels of mother-baby pairs. The prospective study was carried out between July 2018 and February 2020 at the University Hospital of Obstetrics and Gynecology “Maichin dom”, Sofia. The study included 45 full-term newborns and their mothers. Data collected included maternal health, nutrition, vitamin intake, and anthropometric data of the newborns. The laboratory tests performed: maternal serum 25(OH)D levels taken in the third trimester of pregnancy and umbilical cord levels of 25(OH)D. The results show that the mean birth weight was 3234.22 ± 370.29 g and the mean gestational age was 38.13±0.89 weeks. A 25(OH)D sufficiency was found in 58% of mothers and 67% of newborns. A strong positive correlation between maternal and neonatal 25(OH)D concentrations (p = 0.007) was found. A relationship between maternal diet, vitamin supplementation and serum vitamin D levels was observed. The level of 25(OH)D in the umbilical cord in winter is lower than in summer (p = 0.002). Due to the essential role of vitamin D for the normal development of the fetus and the infant, a testing for serum levels of vitamin D during pregnancy is recommended.
Topping at the Seedling Stage Changes the Plant Morphology and Yield of Unbranched Type Soybean
Authors: Chu Guanghong , Zhang Jianxin , Xu Baokun , Wang Cong
Published: April 2023

The crop will be free from the control of apical dominance and the axillary buds will develop into branches after topping. However, there are relatively few studies on this subject of soybean. In order to further improve soybean grain yield, unbranched type high-yield soybean variety was used as test material, and the effects of topping at the first trifoliate stage on soybean plant growth, dry matter accumulation, yield and yield components of five planting densities [15 (D1), 18 (D2), 21 (D3), 25 (D4) and 30 (D5) × 104 plants ha−1] were systematically investigated in this study. The results showed that, the dry matter accumulation increased after topping. Flower number per plant, seed number per plant, pod number per plant, and single-plant yield decreased in conventional-cultivation planting density (D4, topping), but they all increased as the planting density was reduced. D2 achieved the highest yield, with 100-seed weight and yield increased by 8.92% and 5.90% compared to CK (D4, nontopping). The number of branches per plant was significantly and positively correlated with podding node number per plant, flower number per plant, pod number per plant, and seed number per plant. This study demonstrates that the more branches formed after topping, the more conducive to increasing the flower number per plant, pod number per plant under lower density.
Living Legume Mulch as an Effective and Improved Approach in Integrated Soil Management in Intensive Organic Apple Orchards
Authors: Dzhuvinov Vasiliy , Kutinkova Hristina , Staneva Irina , Gandev Stefan , Kornov Georgi , Palagacheva Nedyalka , Akova Vanya
Published: April 2023

The aim of international research project of European Union “DOMINO” was to develop and examine an innovative management strategy in intensive organic fruit orchards: 1) dynamic “living mulches” in the row, such as cash crops with vegetative organs and the sod with legumes between the rows for weed control; 2) fertilization by recycled soil amendments and leguminous crops to increase resource use efficiency and improve ecosystem services, and 3) partly closed covering net systems to support non chemical pest and diseases control.
The content of NH+4 during the second season – 2020 was an increase for on row and inter row forage pea and for inter row white clover variants, because of the leguminous crops sown there. The data for phosphorus for 2020 and 2021 show a clear increasing trend for Golden B variety, which is clearly visible in 2021. Values of K2O for 2020 and for 2021 increase significantly about 2–3 times which meets the requirements for good soil availability. Calcium leads Golden B for inter row white clover variant and for magnesium content for the same variant. The two leguminous crops provided the trees with Mg very well. The highest content of iron in the forage pea variant on row for Golden B and for Granny Smith varieties.
Effects of Vitrification Temperatures and Concentration of Cryoprotective Agents on the Cytoskeleton in Bovine Immature Oocytes
Authors: Zhao Shiyu , Liu Jiaqi , Wang Xiaojing , Liu Yiheng , Li Xiaoxia , Xu Zhiqian , Li Yinghua , Yu Xueli
Published: April 2023

The objective of the research was to evaluate the effect of vitrification temperatures (VTs) and concentration of cryoprotective agents (CPAs) on the cytoskeleton of bovine immature oocytes (BIOs). Bovine cumulus oocyte complexes (COCs) were collected and divided randomly into five groups: (a) fresh control group, (b) oocytes vitrified in liquid helium (LHe; −269◦C with 5.6 M CPAs, (c) oocytes vitrified in LHe (−269◦C with 6.6 M CPAs, (d) oocytes vitrified in liquid nitrogen (LN; −196 ◦C with 5.6 M CPAs, (e) oocytes vitrified in LN (−196◦C with 6.6 M CPAs. The results showed that the developmental level of BIOs in the LHe 5.6 M group was the highest among the four vitrification groups, and the maturation rate and cleavage rate were significantly higher than the other three vitrification groups (P < 0.05). With further experiments, the normal rate of microfilament and spindle in the LHe 5.6 M group was the highest compared with the other three vitrification groups. It was concluded that lower VT (−269◦C and lower CPAs (5.6 M) could significantly reduce damage to the cytoskeleton, which had a positive effect on the development of oocytes after vitrification.
Qualidade de vida no teletrabalho: um estudo de caso na Universidade de Brasília
Authors: Fayad Raphael Fabiano Muniz , Nunes André
Published: April 2023

O artigo tem o objetivo de identificar e descrever a percepção da qualidade de vida no teletrabalho na Universidade de Brasília (UnB). A pesquisa se caracteriza como um estudo de caso quantitativo-qualitativo e teve como público alvo os servidores técnicos e docentes que atuam nos setores estratégicos da UnB. A Escala de Qualidade de Vida no Teletrabalho foi aplicada a uma amostra de 149 servidores e os resultados demonstraram que o teletrabalho implementado no contexto da pandemia de covid-19 obteve índices de bem estar nos fatores de autogestão do teletrabalho, contexto do teletrabalho, infraestrutura de trabalho e estrutura tecnológica, porém houve percepção de mal-estar no fator relacionado à sobrecarga de trabalho.
A tecnologia e a Indústria 4.0 na engenharia de produção
Authors: Da Matta Guilerme Amicabile , Alves Mariana de Carvalho , De Oliveira Nicole Coimbra , Da Silva Vitória Duarte Bastos , De Stefano Ercilia
Published: April 2023

A sigla “vuca” tem sido cada vez mais incorporada ao universo empresarial, pois define o comportamento atual do mercado: volátil, incerto, complexo e ambíguo. Com o aumento da competitividade e do nível de exigência do consumidor torna-se cada vez mais necessária a otimização de recursos e melhoria constante de processos e sistemas, de forma a se atingir a competitividade necessária para estabilização no mercado. Tornando- se, assim, essencial a implementação de ferramentas tecnológicas e de inovação, atreladas às boas práticas de gestão da engenharia de produção. Logo, por meio da pesquisa realizada, buscou-se conceituar a indústria 4.0 e suas respectivas tecnologias, visando compreender a utilização e benefícios práticos das mesmas.
O papel do progresso técnico na apropriação espacial e construção de territórios vitivinícolas
Authors: Jeziorny Daniel Lemos
Published: April 2023

Este trabalho fundamenta-se na convicção de que não há neutralidade na tecnicização do espaço. Ao contrário, entendemos que as escolhas técnicas que direcionam os projetos de apropriação espacial, ou territorialização destes, são fundamentalmente políticas. Diante disso, existe um sentido, uma direção para a apropriação espacial, dada pela lógica do capital e conformada pelo progresso técnico. Com base nesse argumento, procuramos delinear os contornos da apropriação do espaço rural da Campanha Gaúcha por parte de capitais oriundos do território do Vale dos Vinhedos, e apontar o papel do progresso técnico nos processos de apropriação espacial.
Monitoramento e controle no gerenciamento de projetos do setor público brasileiro: uma revisão sistemática da literatura
Authors: Gusmão Gustavo Miranda , De Holanda Jenifer Teixeira , Fialho Hilton Vinícius Maia Lins , Moreira Fábio de Oliveira Pinto , Gomes Douglas de Alencar , Ceolin Alessandra Carla , Cabral Romilson Marques
Published: April 2023

A administração pública brasileira vem caminhando desde a última reforma do estado para o que vem sendo chamado de Nova Gestão Pública (NGP), e, a partir dela, ferramentas e práticas adotadas pela iniciativa privada vêm tendo papel cada vez mais relevante para o setor público. Um exemplo disso é o gerenciamento de projetos, que contribui para resultados mais eficazes e eficientes nos projetos executados no âmbito público a partir das suas áreas de conhecimento e grupos de processo. Este estudo é uma revisão sistemática da literatura, de caráter descritiva e exploratória, que utilizou a base de dados do Portal de Periódicos da CAPES objetivando avaliar como vem sendo abordado o processo de monitoramento e controle nos artigos voltados a pesquisar o gerenciamento de projetos no setor público brasileiro. A constatação após a análise de nove artigos é que a produção a este respeito ainda vem sendo bastante escassa, e utiliza o monitoramento e controle, via de regra, em caráter transversal nas áreas de conhecimento da gestão de projetos, porém abrangendo setores distintos da gestão pública, como universidades, judiciário e forças armadas, e atividades diversas, sendo aplicado em finanças, tecnologia da informação, compras e obras públicas.
A América Latina no Antropoceno: continuidade ou ruptura?
Authors: Jeziorny Daniel , Solanich Hingrid Thainá Costa
Published: April 2023

O objetivo deste ensaio é apresentar uma reflexão acerca da historicidade da forma de apropriação do espaço geográfico da América Latina a partir de sua inserção no contexto do desenvolvimento do capitalismo. Consequentemente de sua inserção no modelo civilizacional do Antropoceno. Sem embargo, as reflexões são enquadradas com um diapasão teórico constituído pela Economia Ecológica. Pela Ecologia Política e pela Ecologia Social.
Fiscal policies for economic sustainability in COVID-19: what do subnational governments in Brazil and Colombia reveal?
Authors: Araújo Jamille Carla Oliveira , De Souza Fernando Gentil , Robles Eduardo Martínez , Celis Laura Margarita Medina , Lagioia Umbelina Cravo Teixeira
Published: April 2023

This research aims to compare public governance response measures regarding the fiscal policies adopted by subnational governments for economic sustainability in Brazil and Colombia in the face of the Covid-19 crisis. Data collection was performed on 92 government websites from 27 Brazilian states and 33 Colombian departments (subnational governments). Through exploratory qualitative analysis, fiscal policies were studied between 2020 and 2021, instituted by laws and decrees. Categorized into two strands: (i) laws supporting the maintenance of economic sustainability and (ii) tax incentives. The main results indicated that in a short time government needed to create methods and tools to adapt to the context of social isolation and revealed fiscal policies to support small businesses. In Brazil, governments have implemented actions: supporting vulnerable people, self-employed entrepreneurs, small businesses, such as granting financial credit. In addition to tax incentives, there was exemption, postponement and payment in installments. In Colombia, a line of credit was granted to support the liquidity of all companies in the tourism sector, the incentives were granted through tax exemptions, except for the tourism and air transport sectors. As much as the incentives launched were aimed at minimizing the impacts of the pandemic and maintaining part of the revenue collected by governments, for both countries the need for tax reform was evident. It should be noted that Colombia started processing the tax reform project in 2021 and on November 4, 2023, it was approved by both legislative houses, and is in the final drafting process. This article theoretically contributes to the expansion of studies that assess economic sustainability and public governance in developing countries in the face of relevant economic crises.
Biomass‐Derived Laser‐Induced Graphene and Its Advances in the Electronic Applications
Authors: Jayan Jitha S , Jayan Sajitha S
Published: April 2023

Due to its porous architecture, laser‐induced graphene (LIG) has become a viable option for prospective use in a variety of sectors, particularly the electrical field. LIG is essential for flexible electronics, especially in bioelectronics, sensors, and actuators; these cutting‐edge applications are made possible by specially designed porosity, electrical conductivity, composition, and morphology. Due to the environmental concerns with the synthetic polymers typically employed for the synthesis of LIG, the production of LIG from biomass is a new step in the direction of sustainable development and blossoming research areas. However, the research is still in its early stages, and there are relatively few studies on the use of LIG generated from biomass. As a result, this study aims to shed light on the developments of biomass‐derived LIG and thereby inspire young researchers.
Impact of Fibrinogen, Fibrin Thrombi, and Thrombin on Cancer Cell Extravasation Using In Vitro Microvascular Networks
Authors: Angelidakis Emmanouil , Chen Sophia , Zhang Shun , Wan Zhengpeng , Kamm Roger D. , Shelton Sarah E.
Published: April 2023

A bidirectional association exists between metastatic dissemination and the hypercoagulable state associated with many types of cancer. As such, clinical studies have provided evidence that markers associated with elevated levels of coagulation and fibrinolysis correlate with decreased patient survival. However, elucidating the mechanisms underpinning the effects of different components of the coagulation system on metastasis formation is challenging both in animal models and 2D models lacking the complex cellular interactions necessary to model both thrombosis and metastasis. Here, an in vitro, 3D, microvascular model for observing the formation of fibrin thrombi is described, which is in turn used to study how different aspects of the hypercoagulable state associated with cancer affect the endothelium. Using this platform, cancer cells expressing ICAM‐1 are shown to form a fibrinogen‐dependent bridge and transmigrate through the endothelium more effectively. Cancer cells are also demonstrated to interact with fibrin thrombi, using them to adhere, spread, and enhance their extravasation efficiency. Finally, thrombin is also shown to enhance cancer cell extravasation. This system presents a physiologically relevant model of fibrin clot formation in the human microvasculature, enabling in‐depth investigation of the cellular interactions between cancer cells and the coagulation system affecting cancer cell extravasation.
Entering Voltage Hysteresis in Phase‐Separating Materials: Revealing the Electrochemical Signature of the Intraparticle Phase‐Separated State
Authors: Katrašnik Tomaž , Moškon Jože , Zelič Klemen , Mele Igor , Ruiz‐Zepeda Francisco , Gaberšček Miran
Published: April 2023

Hysteresis is a general phenomenon regularly observed in various materials. Usually, hysteretic behavior is an intrinsic property that cannot be circumvented in the nonequilibrium operation of the system. Herein, it is shown that, at least with regard to the hysteretic behavior of phase‐separating battery materials, it is possible to enter (deeply) the hysteretic loop at finite battery currents. This newly observed electric response of the electrode, which is inherent to phase‐separating materials, is related to its microscopic origin arising from a (significant) share of the active material residing in an intraparticle phase‐separated state. This intriguing observation is further generalized by revealing that a phase‐separating material can feature (significantly) different chemical potentials at the same bulk lithiation level and temperature when exposed to the same finite current and external voltage hysteresis. Therefore, the intraparticle phase‐separated state significantly affects the DC and AC characteristics of the battery. The experimental evidence for entering the intraparticle phase‐separated state is supported by thermodynamic reasoning and advanced modeling. The current findings will help advance the understanding, control, diagnostics, and monitoring of batteries composed of phase‐separating materials while also providing pertinent motivation for the enhancement of battery design and performance.