bluuebunny/crossref_metadata_2025 huggingface dataset:
Antioxidant activity assay and determination of phenolic and flavonoid content of Libho (Ficus Septica Burm. F) fruits
Authors: Yamin Yamin , Rina Andriani , Sabarudin Sabarudin , Nur Haijah , Henny Kasmawati
Published: October 2022

Background: One of the plants used in Indonesian traditional medicine Libho (Ficus Septica Burm. F) is traditionally used to treat some diseases, including malaria, diarrhea, diabetes, analgesic, antifungal, dysentery, anthelmintic, antioxidant, hemostatic and anti-inflammatory. Purpose: The purpose of the study is to investigate the potential in vitro antioxidant activity assay and phytochemical content of Libho fruits. Methods: Libho leaves powder was extracted with the maceration method Antioxidant activity was evaluated using ABTS cation and CUPRAC radicals. Total phenolic content was determined using the Folin-Ciocalteau method. Meanwhile, the total flavonoid content was determined using the aluminum chloride complex colorimetric method; Results: Extract and fraction of Ficus Septica Burm. F fruits have the strongest antioxidant potential. The ethyl acetate fraction showed the strongest antioxidant activity on both ABTS and CUPRAC radicals with IC50 values of 6.33 ± 0.01 µg/mL and 11.64 ± 0.28 µg/mL, respectively. Ethyl acetate fraction also showed high phenolic and flavonoid content with values of 28 ± 0.05 mg GAE/100 mg sample and 43.08 ± 0.48 mg QE/100 mg sample, respectively. Conclusion: Ethyl acetate fraction has the potential to be used as a source of natural antioxidants and has the potential to be used as a nutraceutical.
DEEP LEARNING AND MACHINE LEARNING MODELS TO FORECAST BSE AND NIFTY SENSEX IT INDEX
Authors: V. Selvakumar  , Satpathi Dipak Kumar , Chhabra Abhinav , Nema Arjita
Published: October 2022

The primary objective of this work is to build an appropriate mathematical model that helps predict the direction of stock market indices. The stock market is volatile and dynamic, and prediction of its movement will help investors make more optimal strategies and boost their profit. In this context, the data was collected from two major IT indices of India, the BSE IT Index and the NIFTY IT Index. In modeling the time series, autoregressive integrated moving average (ARIMA) was used initially, followed by various machine learning models, like artificial neural network (ANN), recurrent neural network (RNN), and convolutional neural network (CNN). The data analysis exhibited superior performance of ANN models compared to other models for performance criteria such as root mean squared error (RMSE) and mean absolute percentage error (MAPE). This exploratory analysis concluded that ANN models outperform other predicting models to greater accuracy, augmenting previous literature on stock market analysis. This machine learning approach would help investors design optimal strategies and boost their profits in the world of stock market.
Anatomical and pathophysiological features of fetal circulation in the umbilical-portal venous system
Authors: Shelayeva Elizaveta V. , Tsybuk Elizaveta M. , Kopteyeva Ekaterina V. , Kapustin Roman V. , Kogan Igor Yu.
Published: October 2022

Being facilitated in recent years by the advent of high-resolution gray-scale, color Doppler and three-dimensional ultrasound, prenatal visualization of venous vessels has improved much and well contributed to a better understanding of the value of fetal venous circulation. The fetal liver plays an important role in ensuring normal fetal blood circulation, receiving up to 7080% of venous return from the placenta. Of particular importance is its role in the regulation of intrauterine growth. Venous inflow to the fetal liver is significantly influenced by maternal factors. Ultrasound evaluation of the fetal venous system remains to be not an easy task. This article discusses the significance and features of the anatomical and functional development of the fetal intrahepatic venous system.
Maternal circadian rhythm and its implications for offspring health
Authors: Evsyukova Inna I.
Published: October 2022

This review presents data on the circadian system hierarchy and its unique reorganization at the onset of pregnancy, which plays a fundamental role in maintaining maternal homeostasis and creating optimal conditions for the implementation of the genetic program of fetal development. A particular emphasis is made on the protective mechanisms of the circadian rhythm of maternal melatonin, which is the primary messenger of biorhythms. This paper thoroughly discusses the mechanisms and consequences of maternal chronodisruption in pregnant women exposed to adverse environmental conditions (shift work, stress, irregular nutrition, etc.), as well as in those with chronodestruction-related diseases (obesity, diabetes mellitus, etc.). Elucidating the circadian system status in the patients and, in particular, whether they have a daily rhythm of melatonin production will determine a new approach to risk assessment and timely prevention of cardiovascular, metabolic, neuroendocrine and mental disorders in the offspring in later life.
Analysis of the pathogenic CYP21A2 gene variants in patients with clinical, biochemical and combined manifestations of hyperandrogenism
Authors: Osinovskaya Natalia S. , Glavnova Olga B. , Yarmolinskaya Maria I. , Sultanov Iskander Yu. , Klyuchnikov Dmitry Yu. , Tkachenko Natalia N. , Nasykhova Yulia A. , Glotov Andrey S.
Published: October 2022

BACKGROUND: The association of heterozygous carriage of pathogenic variants in the CYP21A2 gene with various manifestations of hyperandrogenism remains poorly understood to date.
AIM: The aim of this study was to analyze the relationship between the carriage of pathogenic variants in the CYP21A2 gene in women and various manifestations of hyperandrogenism.
MATERIALS AND METHODS: Clinical description, hormonal testing and molecular genetic analysis of the CYP21A2 gene were performed in 97 women with clinical, biochemical and combined manifestations of hyperandrogenism and in 46 people in the control group. The mean age of the patients was 27.3 0.6 years. Levels of 17-hydroxyprogesterone, dehydroepiandrosterone sulfate and androstenedione were measured in the blood serum of the study participants. To identify pathogenic variants in the CYP21A2 gene, we used next generation sequencing, restriction fragment length polymorphism analysis, real-time polymerase chain reaction, and multiplex ligation-dependent probe amplification analysis. A statistical analysis of the frequency of pathogenic CYP21A2 gene variants in the study groups and hormone levels in different study subgroups was carried out.
RESULTS: In patients with hirsutism, acne, menstrual irregularity, miscarriage and infertility, pathogenic variants in the CYP21A2 gene were identified in 31% (30/97) of cases in the heterozygous state and in 6% (5/97) of cases in the homozygous state. The frequency of these variants (in the heterozygous state only) was significantly higher 6.5% (3/46) of cases, when compared to the control group (p 0.0001). The identified pathogenic variants included both single nucleotide substitutions such as P31L (n = 1), I2splice (n = 1), V282L (n = 15), I173N (n = 3), Q319X (n = 8), R357W (n = 1), P454S (n = 1), and P483S (n = 1) and deletions of various lengths (n = 10). We found no significant difference in the levels of dehydroepiandrosterone sulfate and androstenedione between heterozygous carriers and the control group and between heterozygous carriers and patients with the wild type CYP21A2 gene (p 0.05), while 17-hydroxyprogesterone level in the group of patients with heterozygous changes was higher, when compared to the control group (p 0.001).
CONCLUSIONS: Heterozygous carriage of pathogenic variants in the CYP21A2 gene is associated with manifestations of hyperandrogenism. However, further study of the mechanisms underlying this association is required.
Evaluation of the factors influencing labor outcomes in women with a history of abdominal delivery
Authors: Mochalova Marina N. , Alekseyeva Anastasia Yu. , Akhmetova Elena S. , Mudrov Viktor A.
Published: October 2022

BACKGROUND: The rapid increase in the frequency of caesarean sections has led to the emergence of a special group of patients with a uterine scar who want to give birth through the natural birth canal. Repeated operative delivery is associated with high risks of both intraoperative and postoperative complications, therefore, every year the number of women with a uterine scar who prefer natural childbirth is growing.
AIM: The aim of this study was to create a model that allows, based on a comprehensive assessment of risk factors, for predicting the outcome of childbirth in women with a history of abdominal childbirth.
MATERIALS AND METHODS: We carried out a retrospective analysis of 173 birth histories of women with a uterine scar after a previous caesarean section, delivered in the Chita City Maternity Hospital in 20212022. Three groups of individuals were designed for the study: Group 1 included 110 women delivered by caesarean section in a planned manner; Group 2 comprised 20 women delivered by caesarean section during childbirth, while Group 3 consisted of 43 women who gave birth through the natural birth canal. The groups were comparable in terms of nationality, age, material and social conditions of the patients. On the eve of delivery, all patients underwent general clinical and obstetric ultrasound examination, with the anamnesis details clarified. The data obtained were processed statistically using the IBM SPSS Statistics version 25.0.
RESULTS: Using binary logistic regression, a model was developed to predict the outcome of childbirth through the natural birth canal in women with a uterine scar, which takes into account statistically significant indicators such as gestational age, estimated fetal weight, parity, and the presence of chronic endometritis and weakness of labor activity in history. The sensitivity of the developed prognostic model is 0.86, the specificity being 0.70. The area under the ROC curve is 0.87 (95% confidence interval 0.780.96; p 0.001).
CONCLUSIONS: The comprehensive analysis of risk factors allows for predicting the outcome of natural childbirth in women with a uterine scar, which in the future will optimize the tactics of their delivery and prevent the development of complications in childbirth for the mother and fetus.
Potential Therapeutic Effect of TLR4-Primed Mesenchymal Stem Cells in Lessening Kidney Damages in Rat Model of Diabetic Nephropathy
Authors: Tollabi Mohammad , Ghasemzadeh Navid , Dehghani Firoozabadi Ali
Published: October 2022

Background and Aims: Substantial damage to the kidney tissue and diabetic nephropathy (DN) can be caused by chronic hyperglycemic conditions and exposure to a high level of blood glucose. In the current study, we explored the capability of adipose-derived mesenchymal stem cells (ADSCs) and Toll-like receptor-4-primed mesenchymal stem cells (TLR4-primed MSCs) on kidney regeneration, resolution of inflammation, and alleviation of diabetic nephropathy in DN in the rats.
Materials and Methods: STZ-induced diabetic rat models were divided into 5 subgroups, including 1) DN group, 2) DN group received insulin, 3) DN group received human foreskin fibroblast (DN-HFF), 4) DN group received single pulse of 1×106 cells of MSCs and 5) DN group received single pulse of TLR4-primed MScs. Thereafter, biochemical and histological analysis was performed on DN-model groups. Biochemical analysis exhibited a blood urea nitrogen level recovery in both MSCs and TLR4-primed MSCs-treated groups. Administration of MSCs also up-regulated mRNA expression of Bcl-xL, while the expression of Bax was significantly down-regulated.
Results: Histological and molecular results showed that TLR4-primed MSCs have an anti-inflammatory and anti-apoptotic effect on inflamed kidneys and effectively reduced DN indicators in the TLR4-primed MSCs group compared to the unprimed MSCs group.
Conclusion: Priming with LPS improves the therapeutic effects of MSCs in the rat model of DN, consequently lessening the symptoms of DN rats. This study proposes that primed MSCs can be served as a potential therapeutic approach in diabetes mellitus and DN management.
The Effects of Atorvastatin Consumption on Biochemical Variables in Patients with Type 2 Diabetes Mellitus and Pre-diabetes
Authors: Nosrati Andevari Ali , Moein Soheila , Qujeq Durdi , Moazezi Zoleika , Hajian-Tilaki Karimollah
Published: October 2022

Background and Aims: Atorvastatin may alter glycemic traits and lipid profiles. This study aimed to evaluate the effects of atorvastatin on biochemical variables in patients with type 2 diabetes and pre-diabetes (borderline diabetes).
Materials and Methods: This study included 80 individuals divided into five groups. Patients with type 2 diabetes mellitus and pre-diabetes used atorvastatin 20 mg/day for three months. After three months, variables such as serum fasting blood glucose (FBS), cholesterol, triglyceride, low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and glycosylated hemoglobin (HbA1c) levels were measured to assess the status of diabetes and pre-diabetes condition. Linear regression was applied to determine the association between atorvastatin uses and alters of biochemical variables levels.
Results: The serum FBS and HbA1c levels in patients with diabetes and pre-diabetes who use atorvastatin were significantly lower than in patients with diabetes and pre-diabetes who did not use atorvastatin (p=0.001). Serum cholesterol and LDL-C levels decreased in diabetic and pre-diabetic patients who used atorvastatin in comparison with diabetic and pre-diabetic patients who did not use atorvastatin (p=0.001). In patients with pre-diabetes, the use of atorvastatin slightly increased serum HDL-C levels. However, in patients with diabetes, the use of atorvastatin slightly decreased serum HDL-C level (p= 0.001). Diabetic and pre-diabetic patients who use atorvastatin significantly decreased serum triglyceride levels (p=0.016), while in diabetic and pre-diabetic patients, using atorvastatin slightly increased the serum insulin level (p= 0.003).
Conclusions: Atorvastatin using alters fat and sugar indices in diabetic and pre-diabetic patients.
Performance Comparison of Two Different Branded Blood Collection Tubes Used in Biochemistry Laboratory
Authors: Ozdemir Ali Volkan , Mizrak Soycan , Demir Metin
Published: October 2022

Background and Aims: Blood collection tubes (BCT) with gel separators are diagnostic devices that can affect all laboratory processes. In this study, the aim was to compare the performance of a new brand of BCT with the sample tubes that are well-known and widely used in the market.
Materials and Methods: Blood samples were taken from 50 healthy volunteers to two brands of BCTs (KWS and BD Vacutainer SST II Advance) by providing standard conditions. The nine most requested test parameters were determined and analyzed simultaneously. The results were analyzed using the SPSS 21 software.
Results: There was no significant difference in the results of most tests of the new brand tubes compared to the Becton-Dickinson brand tube, and the bias calculated for the tests except calcium and potassium was detected to be lower than the desirable bias.
Conclusion: It was determined that the test parameters analyzed in both tubes were in statistical agreement. The percentage of bias value of calcium and potassium tests in KWS branded tubes is higher than the desired value. In addition, constant and proportional errors were determined for the calcium test. These test parameters should be analyzed in larger patient groups. Therefore, KWS tubes can be accepted for routine laboratory operations.
Antiviral Activity of Arnebia Euchroma and Amniotic Membrane against HSV-1, Rotavirus, and Influenza Virus
Authors: Saghafi Mohammad Mehdi , Tavakoli Ahmad , Ahmadi Shahnaz , Monavari Seyed Hamidreza
Published: October 2022

Background and Aims: Currently, there are antiviral chemicals used to treat viral infections accompanied by limitations such as high levels of toxicity and adverse effects in humans, the emergence of drug-resistant viral strains, low numbers, and limited diversity. Therefore, it is necessary to evaluate new photochemical to obtain new therapeutic methods. The present study was conducted to evaluate the antiviral activity of Arnebia Euchroma (A. Euchroma) extract, amniotic membrane, a mixture of A. euchroma extract and amniotic membrane and its carrier (comprised of Sesam and ostrich oil) against three different viruses, including Herpes simplex virus type 1 (HSV-1), influenza A, and rotavirus in-vitro.
Materials and Methods: A methyl thiazolyl tetrazolium (MTT) assay was performed to evaluate the cytotoxic effect of the above compounds on Vero, MDCK, and MA-104 cell lines. After the determination of non-toxic concentrations, Tissue culture infection dose 50 (TCID50) test was performed to determine antiviral activity.
Results: Among all the above-mentioned compounds, the combination of A. euchroma extract and amniotic membrane at the highest non-toxic concentration for the cells had the highest antiviral activity against all three viruses, leading to 1 log10 TCID50 reduction in influenza A and HSV-1 titers and 0.6 log10 TCID50 reductions in rotavirus titer when compared to the virus control.
Conclusions: The combination of A. euchroma and amniotic membrane can be considered a new antiviral agent to treat viral infections.
The effect of erythropoietin on blood parameters in thalassemia intermedia patients
Authors: Hashemi Azam Sadat , Soroush Morteza Zangeneh , Sheikhpour Elnaz , Ghanizadeh Fatemeh , Shamsi Farimah , Fallah Bahareh , Kazemy Leila
Published: October 2022

Background: β-thalassemia is the most common hereditary disease in Iran, and more than 2 million carriers of β-thalassemia live in Iran. On the other hand, our country is located in the thalassemia belt, and no comprehensive study has been conducted regarding the effect of erythropoietin on blood parameters in thalassemia intermedia patients in our region. Therefore this study aimed to investigate the effect of erythropoietin on blood parameters of thalassemia intermedia patients.
Materials and Methods: This prospective cross-sectional study was conducted on all patients suspected of thalassemia intermedia in Shahid Sadoughi hospital from March 2021 to M 2022.  In the case of diagnosis of microcytic anemia, an electrophoresis test was performed, and people diagnosed with thalassemia intermedia entered the study. Then patients were divided into two groups (the intervention and control groups). The erythropoietin dose was 50-100 units/ kilogram (body weight) three times a week for six months. The measurement of hematocrit and hemoglobin were done using CBC cell counter (Sysmex KX21). Other data were extracted from medical records.
ResultL: In the current study, the mean age of patients in the intervention and control groups was 9.15±1.53 and 8.35± 6.90 years old, respectively (p=0.9). The mean hematocrit level in the intervention and control groups was 28.05± 4.06 and 23.45± 3.22 %, respectively (P<0.001). The mean hemoglobin level in the two groups was 9.15± 1.53 and 7.65± 1.23 g/dL respectively (p=0.002). The mean hematocrit level before and after the intervention was 25±3.71 and 28.05±4.06 %, respectively. The mean hemoglobin levels before and after therapy were 7.9±1.52 and 9.15±1.53 g/dL, respectively.
Conclusion: According to the findings, hemoglobin and hematocrit increased in thalassemia intermedia patients taking erythropoietin. Therefore it seems that recombinant erythropoietin can be helpful in these patients.
A comprehensive in silico analysis of pathogenic nsSNPs in the NT5C2 gene involved in relapsed ALL
Authors: Chamani Reyhane , Pourhesseini MahmoudAbadi Parnia Sadat , Janati Yasamin , Tajdini Roxana
Published: October 2022

Background: About 10-20% of children suffering from acute lymphoblastic leukemia (ALL), experience a relapse, which is a major cause of their death. Purine nucleotide analogs are frequently prescribed to maintain the treatment of ALL. Cytosolic 5´-nucleotidase (NT5C2) catalyzes the 5´ dephosphorylation of purine analogs. Gain-of-function mutations in the NT5C2 gene result in resistance to the treatment with purine analogs and subsequently in the relapse of the disease.
Materials and Methods: In this descriptive study, bioinformatics tools were used to assess the effect of single nucleotide polymorphisms (SNPs) in the NT5C2 gene on the function and structure of the protein. So, 352 missense variants were retrieved from the NCBI database and analyzed by SIFT, PROVEAN, PMut, PANTHER, PolyPhen2, SNPs & Go, and PhD-SNP servers. Then, structural evaluations were performed using HOPE, NetSurp-2.0, and PyMOL. Moreover, stability and evolutionary preservation were assessed by I-Mutant2.0 and ConSurf, respectively.
Results: As many as 31 nsSNPs were predicted to be affecting the protein function and stability. Also, the native residues were found to be evolutionarily preserved. The structural evaluation demonstrated that a change of hydrophobicity, flexibility, size, charge, or surface accessibility due to 24 nsSNPs would lead to the change of noncovalent interactions and then the conformation of the protein.
Conclusion: Identification of biomarkers is significant in the prediction of relapses in ALL children. In this study, bioinformatics tools served to identify 24 high-risk deleterious nsSNPs in the NT5C2 gene. These mutations can be used to predict resistance to chemotherapy and relapse in ALL patients.
Hematopoietic stem cell transplant therapy, clinical trials, complications, and quality of life for patients with Sickle cell anemia: Clinical potential and future perspectives
Authors: Verma Henu Kumar , Kumar Ratre Yashwant , Bhaskar L.V.K.S , Sahu Tarun , Purushottam Lingojwar Devendra
Published: October 2022

Background: Sickle cell anemia (SCA) is an inherited monogenic disorder. The clinical symptoms of SCA are protean, including vaso-occlusion, hemolysis, early stroke, leg ulcers, multi-organ failure, and increased risk of premature death. Hematopoietic stem cell transplantation is the only treatment identified to reduce SCA-related organ damage. Unfortunately, graft rejection is a significant impediment to these strategies.
Materials and Methods: The current standard of treatment for the past two decades is limited to myeloablative-matched sibling donors, which is likely to be only for minor patients and is feasible for non-malignant giant disease. Cumulative studies showed that HSCT increases overall survival and quality of life in patients with SCA.
Results: Hematopoietic stem cell transplantation (HSCT) is significantly associated with a higher risk of graft versus host disease and moderate mortality risk. New strategy lacking standard donors includes cord blood, matched unrelated donors/ Haploidentical donors.
Conclusion: This review summarized evidence from HSCT clinical trials from different transplantation methods, specific HSCT and HSCT-related health problems that need to be addressed in medical contexts with patients and family members, and other areas that enhance the quality of life in SCA.
Kryzys Europy — kryzys sprawstwa
Authors: Bogusławski Marcin Maria
Published: October 2022

W artykule stawiam tezę, że źródłem niepokojów, które trawią Europę, jest kryzys sprawstwa. Za Alainem Touraine’em i Josephem E. Stiglitzem staram się pokazać, że jednym z ważniejszych źródeł kryzysu sprawstwa są nierówności ekonomiczne i kapitalizm finansowy. Twierdzę także, że remedium na kryzys są działania mające na celu przywrócenie sprawstwa jak największej liczbie aktorów.
Niezrównoważenie w kryzysie
Authors: Szymański Wojciech
Published: October 2022

W czasach kryzysu Europy nadmierne koncentrowanie się na kwestiach rynkowych i gospodarczych w analizowaniu przyczyn i szukaniu rozwiązan wspo łczesnych problemo w wydaje mi się działaniem niedostatecznym. Co więcej, uwazam za niebezpieczne zaniedbywanie dobrobytu obywateli rozumianego szerzej niz dostatek zasobo w finansowych. W niniejszej pracy, korzystając z badan naukowych prowadzonych w celu odnalezienia korelato w deklarowanego poziomu szczęscia/dobrostanu (SWB, Subjective Well-Being), uznawszy je za najtrafniejszy miernik skutecznosci polityki danego rządu, chciałbym pokazac alternatywne do najbardziej obecnie rozpowszechnionych teorii szczęscia. W pracy przedstawiam poro wnanie dwo ch dominujących ostatnimi czasy wspo łczynniko w, uz ywanych w mierzeniu sukcesu danej polityki (IEF - Index of Economic Freedom oraz GCI, Global Competitiveness Index) ze stosunkowo niedawno stworzonym trzecim (SDGI, Sustainable Development Goals Index), prezentując badania wykazujące najwyzszą moc tego ostatniego w przewidywaniu poziomu dobrostanu jednostek.Jesli wyniki tych badan mozna uznac za poprawne, oznacza to, ze obecne, uwazane przez niekto rych za nader redukcjonistyczne, podejscie do kwestii poprawy losu obywateli jest mylne i nalezy przynajmniej rozwaz yc inną drogę. Jedną z propozycji „innej drogi” przedstawiam w skro cie w formie opisu celo w paradygmatu zro wnowazonego rozwoju.
El Turismo Sostenible en Ecuador: reflexiones constitucionales y legislativas
Authors: Ruperti León Leo , Ruperti Rubira Leonardo Santiago , Montilla Pacheco Argenis de Jesús
Published: October 2022

El trabajo tiene como objetivo analizar los preceptos constitucionales y legales del turismo sostenible en el Ecuador. La investigación es de tipo bibliográfico con nivel descriptivo, de acuerdo con esto, el método utilizado es el analítico. Se justifica desde cuatro ópticas, a saber: el lado práctico porque se han convertido en costumbre los traslados de una zona a otra por diferentes motivos; desde una justificación teórica porque la investigación promueve y genera antecedentes en la materia, desde lo social debido a los cambios constantes en las actuaciones de los sujetos participantes en la actividad turística, y por el aporte metodológico que trae aparejada la generación de nuevos conocimientos. Se concluye que el turismo es un fenómeno complejo que toca diversas perspectivas económicas, culturales, sociales, jurídicas, ambientales, entre otras, que ameritan asumir al turismo no como el mero traslado sino el enriquecimiento en vivencias, conocimientos y experiencias de las personas que lo realizan, lo cual debe cumplir con el respeto y cuidado de las zonas que se constituyen en necesidad o atractivo turístico, en todo caso con protección de la naturaleza para configurar el Buen Vivir
The impact of education on language use in the Algerian context: Case of the Nedroma Speech Community
Authors: Ammour Naima , Belmekki Amine
Published: October 2022

Nedromi speakers, especially the new generation, tend to correct some mistakes that they believe are stigmatised features in their speech and thus they try to shift to Modern Standard Arabic. This research paper aims at examining the impact of education on language use, which highlights the sociolinguistic variable, mainly that of education and age, and how it may affect the linguistic behaviour in Arabic. A Nedroma speech community is the sample population. This study emphasises phonological, morphological and lexical levels of analysis, trying to make use of both quantitative and qualitative methods. Such an analysis is viewed to help us understand some of the reasons behind such a change in linguistic behaviours essentially motivated by the influence of education. The results show that the choice of certain linguistic features by the individual is determined by the speaker’s age category, his level of education and, most importantly, his attitude towards certain linguistic characteristics.
Keywords: Age, Algerian context, education, language variability, linguistic features, Nedromi Arabic
The Dark Side of the Tongue: The Stomatology Point of View on Oral Hyperpigmentation
Authors: Seixas Rui , Ribeiro Natacha , Matos Carlos
Published: October 2022

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Comparative Analysis of Islamic and Conventional Banks Performance Using Sharia Maqasid Index and CAMEL
Authors: Rismayani Gista , Nanda Ulfa Luthfia
Published: October 2022

This research was conducted by analyzing the performance of Islamic banking and conventional banking using the sharia maqasid index approach and the CAMEL approach and comparing them. The data source used in this research is the audited and published annual reports from each of the bank websites that will be studied. In addition, other data sources used were obtained through Islamic banking statistics, articles, Bank Indonesia statistics, and others related to research. The results showed that there were significant differences in the performance of Islamic maqasid, the ratio of CAR, NPL, ROA, and FDR of Islamic Commercial Banks to Conventional Banks. The results of further research reject the hypothesis that there is no significant difference in the ratio of NPM and BOPO of Islamic Commercial Banks to Conventional Banks.
Strategies to Increase Financial Inclusion through Financial Technology
Authors: Basrowi Basrowi
Published: October 2022

The purpose of this study is to describe the strategy of increasing public financial inclusion through the use of fin-tech finance. The method used is descriptive qualitative. Data is obtained from secondary data sourced from the official website of Indonesian banks, financial service authorities, and the finance ministry from 2015-2018. Data were analyzed using theme analysis of an overview of the development of fin-tech in Indonesia over the past four years, and the benefits of fin-tech in improving financial inclusion in Indonesia. The results of data analysis show that, first, the development of fin-tech in Indonesia has exceeded the needs of fin-tech itself. Secondly, the development of fin-tech has been able to increase the financial inclusion of the community even though it is only very small at 0.8%.
The Role of BMT in Increasing Islamic Financial Literacy in Society (Case Study in BMT Amanah Ummat Taram Kecamatan Harau)
Authors: Utamy Hebby Rahmatul , Putra Muhammad Deni , Amelia Frida , Utama Wahyu Putra
Published: October 2022

One of the reasons for the low public transactions in Islamic banks is their low Islamic financial literacy. Financial literacy is the level of knowledge, skills, trust in financial institutions, along with their products and services. The objective of this research is to understand the role of BMT in increasing Islamic financial literacy among society. This study is field research in nature. The study employed descriptive analysis with a qualitative approach, and the data were collected through interviews and documentation. The study was conducted in BMT Amanah Ummat Taram, Kecamatan Harau, Kabupaten Limapuluh Kota. The result showed that Islamic financial literacy is of the utmost importance in society. The society could carry out economic activities under Islamic law and start to move from conventional financial institutions to Islamic financial institutions, such as BMT. Efforts have been taken by BMT to increase Islamic financial literacy. These efforts are the socialization of the Islamic economy, communal Qur’an reading, and skill coaching to improve the quality of internal human resources. Improvements in BMT efforts are including introducing transaction agreements and BMT products to increase customers’ knowledge, promoting products and services through social media to increase customers’ trust, and educating financial management and saving to increase customers’ skills. The main obstacles faced by BMT in their efforts increase Islamic financial literacy is the mindset of the society, education, and lack of skilled and competent staff.
Examining the Belief on God and Higher Power through Mental Status and Mental Functioning of Recovering Addicts of Kolkata, India
Authors: Dutta Tinni , Halder Disha
Published: October 2022

In the present day there is a rapid growing interest in the arena of Psycho-spirituality and Mental Health. We need to bear in mind that the spiritual is co-extensive with the religious conception. We identify what we call the spiritual life with a concern to acquire holiness and a sense of presence of God through prayer, meditation and yoga practices. Believe in God transform individual’s identity and enhance ego functioning and status of wellbeing.  The cosmic image of ‘The Tree of Life may have been intended to help man in diversity, which in the life of the mind is called the discovery of meaning’. (Needleman, J,1973). Victor Frankl as quoted by Mc Clone, K (2003) stated that substance abuse might be a response to a loss of direction within the individual. Loss of freedom is perceived as the addictive substance claims possession’. Keeping these in mind the author tries to examine the relationship between the mental status and mental functioning of the addicts who have believed in God and those who don’t believe. After welcoming the clients’ mental status examination was conducted.  Appearances and behavior were noted. Some questions were asked and responses were recorded.  Similarly, ego functions assessment was consisted of both observations and semi-structured interviews. Differences are found to be significant at both .05 and .01 level in case of mental status examination, in case of ego functioning it was significant only at .05 level. Results are indicative of recovering addicts who believe in God would see the colorful aspect of life than who don’t believe in God. They adopt a flexible approach for desired success in lives.
Patriarchal System in Arabic Grammar
Authors: Huda Ribut Nur
Published: October 2022

The aim of this research is to find out the extent of the relationship between Arabic grammar and the patriarchal system in the Arab and Islamic society, which is represented in the well-known rule; Masculinity is more honorable than femininity. And the analysis of this relationship is his process under the approach of the philosophy of language, where he sees language as a living being with a linguistic context and a socio-cultural context. The researcher used the analytical and historical description method, taking advantage of the Sapper-Worf hypothesis (each language has a special grammatical structure), and from the theory of the companion Omar Ibn Al-Khattab (that the Arabic language is part of religion). After the depth of the analysis, the research concluded that the pattern of thought for grammatical predominance is like the constituent mind, with evidence that the nature of language is lightness in pronunciation or sound. As for the pattern of thought of the patriarchal system, it is like the made-up mind with evidence that the concepts of the text from the Qur’an and the Sunnah are affected by natural grammatical or abstract linguistic thinking. This research confirmed that the role of grammatical predominance in the patriarchal system is reflected in the level of Arabic-Islamic language and culture, and also that reflection appears in the level of belief and Sharia prominently. It is recommended that the subsequent researchers examine another topic of philosophical value in the same linguistic and cultural context, in order to understand the extent of external consistency in the relationship between the two contexts.
Addressing Beijing Platform for Actions’ (BPfA) Area of Concerns Experienced by Women and Girls: Assessing the Indonesian, Kosovar, and German Repatriation Policies
Authors: Veronika Nuri Widiastuti
Published: October 2022

The demise of ISIS in 2017 brought about dilemmatic situations for some governments in dealing with the issues of foreign terrorist fighters (FTFs), especially women and children currently living at Northern Syrian camps. Women and children experience poverty, lacking access to education, minimal access to healthcare, violence against women, violation of women’s human rights, media stereotyping of women and girls’ vulnerabilities, which have been identified as parts of the 12 critical areas of concern addressed within the Beijing Platform for Action (BPfA), an international framework to protect the rights of women in armed conflicts. Employing Feminist Security Studies as the framework for analysis, this paper analyses how the areas of concern of BPfA experienced by women and girls in the camps have been responded by the government’s repatriation policies. This paper is a qualitative study by employing semi-structured interviews for the primary data collection complemented with relevant policy documents and secondary data from scholarly articles and media reporting. This paper discusses some areas of concern addressed in BPfA experienced by women in ex-ISIS camps and investigate countries responses to these concerns by looking at the Indonesian, Kosovar and German governments’ experience.  The results of this study show that policies taken by most governments in dealing with repatriation issues have not considered the Beijing Platform for Actions’ strategic objectives resulting in further deprivation and human rights violation dealt by women and girls in the camps.
A Corpus-Based Pilot Study of the Pop Lyrics on Billboard
Authors: Yang Chen
Published: October 2022

Although pop music is endorsed as one of the most leisure activities to express feelings and emotions in people’s daily life, song lyrics are usually neglected by linguists and excluded in any of English corpora (e.g., BNC and ANC) that are currently adopted. The current study focuses on an analysis of lyrics based on a Billboard music chart corpus mainly containing American pop lyrics, via both qualitative and quantitative methods, and aims to investigate to what extent the lexico-grammatical features of the words and expressions used in lyrics enable those songs widely accepted by audience. Results reveal that conversational contexts in the lyrics mark a story-telling feature, and help audience easily realize artists’ attitudes and the implications to some events and scenarios.
The Escalation of Disregard on Normative Economy in the Era of Pandemic
Authors: Samad Telsy Fratama Dewi , Adnan Ahmad Azrin Bin , Shah Hassan Shakeel
Published: October 2022

Covid-19 as a global pandemic spreading around the sphere is not only inducing issues on health but also in economic crisis, particularly on business. The purpose of this research is to reveal fraud scandals and presents the importance of implementing normative economy by following business ethics, seeing it from Islamic economic viewpoint which has been done by Prophet Muhammad and how to prevent future fraud scandal which one of it is from religion. This research used a qualitative method with a descriptive approach. The result of this research reveals that it is important to implement normative economy as it possesses an influence on economic development and stability to society as well as exhibits that fraud cases can be prevented earlier by building the awareness of normative economics through education from the micro to macro scale. The micro-scale is from the family circumstance and from the religion.  Islam as a religion that gives guidance to overall human activities, emphasizes a lot about following norms. For instance, Prophet Muhammad taught a lot how to run the business according to the right norms and following the value of ethics. On macro-scale business ethics also can be taught at school. We concluded that the awareness of normative economics can be taught since the child phase by parents, by religion, and at education institutions to prevent future fraud scandals, particularly in the age of economic crisis.
Maqasidi Analysis in the Fatwa of the Indonesian Ulema Council on the Replacement of Friday Prayers with Dzuhur During the Pandemic
Authors: Aziz Muhammad Abdul
Published: October 2022

The Covid-19 Pandemic limitations affected religion and soul in the community. This included prayer decisions such as, a Muslim observing the Friday prayer in a red zone during the pandemic chose religion, while one who conducts Dzuhur chose the soul. Therefore, this study used the analytical-descriptive method to explain the maqasid al-shari'ah perspective in the Indonesian Ulema Council (MUI) fatwas on the permissibility of replacing Friday prayers with Dzuhur during the pandemic. The results showed that this replacement contradicted the maqasid-masalih concept which views them as inseparable entities. It was against the comprehensiveness (shumuliyyah) principle as the main characteristic of maqasid al-shariah. This is because they lacked elasticity (murunah) which is religion main goal (al-daruriyyat al-khams). The issued MUI fatwas followed the maqasid al-shariah as comprehensive, dynamic, and elastic.
Development of the Methodology of Early Foreign Language Teaching in Modern Research
Authors:   Herzen State Pedagogical University of Russia, Aleksandra G. Gogoberidze , Aleksandra S. Osipova ,   Herzen State Pedagogical University of Russia
Published: October 2022

The article describes the results of the research, revealing the analysis of dissertation research devoted to two areas: firstly, the problems of teaching foreign language methods, and secondly, the problems of teaching and educating preschool children. The purpose of the research is to determine the ways of developing the methodology of early foreign language teaching. As a result, a quantitative and qualitative analysis of 123 dissertation studies on scientific specialties 13.00.01 General pedagogy, history of pedagogy and education, 13.00.02 Theory and methodology of teaching and upbringing (by fields of education), 13.00.08. Theory and methodology of vocational education, for the period from 2012 to 2021, that allow to determine the main directions of the methodology development of early foreign language teaching. The question of the interdisciplinary orientation of the works is considered. Scientific developments are devoted to the methodology of early teaching foreign languages, in particular, the integration of foreign language education in the process of education of value orientations, moral education, intellectual development, the development of speech communication. It is concluded that most studies in the field of foreign language teaching methods are devoted to the formation of language sub-skills, speech skills, and the formation of competencies, however, they are focused on school-age students, adult learners. Insufficient attention is paid to the methodology of early learning of foreign languages; despite the fact that many local and foreign researchers believe that preschool children are ready for foreign language learning. Dissertation research is devoted to education and upbringing of preschool children studies aspects such as the formation of cognitive interest, development of socio-personal qualities, formation of emotional and moral guidelines, study of general pedagogical principles that contribute to the development of preschool children, that is, first of all, pedagogical aspects, while methodological aspects of teaching a foreign language are integrated into the process of upbringing a child.
Doctor of Biology Nina Gomboeva: Harmony of Human Relations
Authors: Aleksandr N. Novikov
Published: October 2022

An essay is presented about Nina Gyndunovna Gomboeva, who has made her career at the Geography department from an assistant to a professor. Twice she was the head of the department; she created a master’s degree in geographical education at the department. In 2021, she celebrated her 70th anniversary, and in 2023 the department celebrates its 70th anniversary. The fate of Nina Gyndunovna is closely connected with the history of the department. Nina Gyndunovna has her own view of this history, which is of great interest both for historical and scientific research on the geography of higher education in the Transbaikal Region and for students, graduates, teachers who have connected their lives with geographical and pedagogical sciences. Doctor of Sciences Gomboeva has tried to highlight the activities of all teachers, to characterize their best qualities. Scientific researches by N.G. Gomboeva fit into the direction of medical geography, or rather, they can be defined as the geography of the physiological adaptation of a person to the physical and geographical conditions of the Transbaikal region. Nina Gyndunovna has a thorny path in science, but her intellect, talent, positive attitude towards people have helped to overcome all difficulties and achieve success.
Graduation Qualification Works of Undergraduate and Graduate Students in Geographical Education: Types and the Need to Use Foreign Developments
Authors:   Transbaikal State University, Aleksandr N. Novikov
Published: October 2022

The graduate qualification work (GQW) is analyzed as a result in the student’s education system, the implementation and protection of which provides for the maximum, in comparison with academic disciplines and practices, the number of competencies. The issue of the organization and primary installations of research activities in the format of the implementation of the GQW is considered. Two primary problems are analyzed that need to be thought about even before choosing and formulating the topic of the GQW: the choice of the work’s type and the need to take into account modern international experience in pedagogical research. These two problems are closely interrelated. For theoretical generalizations, a large array of information is needed, as well as a mastery of a variety of concepts and topics. The absence of foreign concepts in the student’s “theoretical baggage” impoverishes this diversity and limits its possibilities. Among the leading research methods are: typological approach, observation and abstract methods. All GQWs can be divided into four types: practical, theoretical, combined and compilation. Practical work is more often performed by correspondence students who work at school and generalize their pedagogical experience. Theoretical works are written more often by full-time students. Combined works are an attempt to combine theoretical and applied formats. Compilation works are found, although teachers have a policy of removing them from protection and revision. The use of foreign developments is a mandatory requirement of the Basic Professional Educational Program of Higher Education for Bachelor’s Degree, which means that it is automatically extended to the work of undergraduates. But the obligatory presence of theoretical research in the GQW is required only for undergraduates, that is, purely practical work with a review of someone else’s theoretical tools is allowed for bachelors.