bluuebunny/crossref_metadata_2025 huggingface dataset:
Práticas artísticas comunitárias e participações cívica e política
Authors: Cruz Hugo
Published: October 2021

Este artigo remete para um estudo desenvolvido no Brasil e em Portugal no contexto das práticas artísticas comunitárias, particularmente, as teatrais. Este campo tem tido uma forte expansão nos últimos anos, quer do ponto de vista da prática como da produção acadêmica, captando a atenção de distintas áreas disciplinares. A criação artística contemporânea tem-se interessado, cada vez mais, pela integração da dimensão participativa nas suas práticas. Em simultâneo, a educação comunitária, a ação social e o ativismo têm desenvolvido propostas que aprofundam a conexão com as linguagens artísticas. O presente estudo teve como objetivos identificar as potencialidades e fragilidades dos processos criativos desenvolvidos em seis grupos teatrais, três de cada país, assim como aprofundar a relação entre estas práticas artísticas e a participação cívica e política. Baseado numa abordagem qualitativa, o estudo recorreu a entrevistas e grupos focais, tendo contado com a colaboração de oitenta pessoas, entre artistas não profissionais, profissionais e parceiros dos grupos. As principais reflexões permitem apontar para uma atualização dos elementos definidores das práticas artísticas comunitárias, a relevância da qualidade de participação cultural e artística, bem como para as concepções de teatro desenvolvidas e os efeitos percebidos que sugerem diferentes contornos na relação entre estas práticas e a participação cívica e política.
Dual repair of traumatic flank hernia using laparoscopic and open approaches: a case report
Authors: Heo Yoonjung , Kim Dong Hun
Published: October 2021

Traumatic flank hernia (TFH) is rare and prone to recurrence, which makes appropriate treatment challenging. No current guidelines define the optimal timing and method of repair. Meanwhile, recent advances in laparoscopic techniques are reshaping the options for the treatment of TFH. A dual approach that utilizes both laparoscopic and open methods has not previously been reported. Herein, we present the successful treatment of TFH after blunt trauma. A 46-year-old male patient underwent elective herniorrhaphy on hospital day 3, in which laparoscopic implantation of a sublay mesh and extracorporeal implantation of an onlay mesh were performed. Such techniques may be appropriate and result in feasible outcomes in hemodynamically stable patients with large TFH who are strongly suspected of having bowel herniation or concomitant intraperitoneal injuries. Larger studies are needed to assess the long-term results.
Construção e validação de uma tecnologia educativa para educação em saúde no planejamento familiar
Authors: De Lima Ana Paula , Missio Lourdes
Published: October 2021

O uso de tecnologias educativas por profissionais da área da saúde é uma crescente realidade. O objetivo deste estudo foi construir e validar uma tecnologia educativa para o planejamento familiar. Trata-se de uma pesquisa de desenvolvimento metodológico. O seu processo ocorreu em três etapas: construção, validação e encaminhamento à gráfica, resultando em um manual intitulado “O que é planejamento familiar?”. A tecnologia educativa desenvolvida poderá ser um instrumento facilitador e mediador na educação em saúde.
Estudo de caso: estratégia de ensinagem no contexto da educação profissional e tecnológica
Authors: Castaman Ana Sara , Tommasini Angélica
Published: October 2021

O presente estudo tem por objetivo conhecer sobre as estratégias de ensinagem na Educação Profissional e Tecnológica (EPT), de modo a compreender acerca do emprego do estudo de caso no contexto do Programa Nacional de Integração da Educação Profissional com a Educação Básica na Modalidade de Educação de Jovens e Adultos (PROEJA), em uma instituição de ensino federal. Para tanto, a partir de uma abordagem qualitativa, pautada na técnica bibliográfica e no relato de experiência, busca-se: a) examinar sobre as estratégias de ensinagem na EPT; b) refletir acerca do emprego do Estudo de Caso, enquanto estratégia de ensinagem no PROEJA. Conclui-se que o estudo de caso é uma estratégia de ensinagem importante e potencial no PROEJA para desenvolver a criticidade, a autonomia e a participação do estudante, por meio de imersão profissional, pesquisas de campo e em grupo. Além disso, permite explorar e compreender os fatores determinantes e consequentes da realidade, das rotinas e das práticas da situação-problema.
Gestão democrática e formação de professores
Authors: Casagrande Ana Lara
Published: October 2021

Ao refletir sobre gestão democrática e formação de professores no Brasil, com ênfase no caminho traçado para a cidadania, no Estado patrimonial, na universidade pública e no papel dos formadores de professores diante dos mecanismos de participação, este texto objetiva problematizar a formação de professores como um eixo fundante da promoção dos valores que fomentam a atuação voltada para uma gestão democrática na escola, bem como o entendimento da sua importância. Para cumprir com tal objetivo, é feito um estudo exploratório, de abordagem qualitativa. Partimos do pressuposto de que, na Educação Superior, a discussão crítica sobre o papel do Estado e a participação popular estimulam a formação de professores comprometida com  uma proposta de educação (e gestão) conduzida por um processo efetivamente democrático. Esse adjetivo empregado junto ao Estado brasileiro tem um caminho complexo e lento de firmamento de raízes em solo não tão fértil, o que faz com que seja necessário discutir tais idiossincrasias, temendo ventos fortes no sentido contrário, que abalem o pouco de sombra que se formou até aqui.
IDENTIFIKASI KARAKTERISTIK KORBAN KECELAKAAN LALU LINTAS DI SIDOARJO TAHUN 2016
Authors: Septianingtyas Daniar Mukti
Published: October 2021

Traffic accident becomes a very serious case because it causes not only material loss but also physical and psychological harms to the subject and the people around him. Accidents that occurred resulted in not only injuries but also death. This study aims to identify characteristics of traffic accident victims in Sidoarjo in 2016. It was an observational study with cross sectional design and based on daily data of traffic accident with 735 samples. Data were processed by ordinal logistic regression statistic test. In this case, variables of the study included the severity of victim, age, gender, profession, time of occurrence, type of collision, and type of vehicle. The results of characteristic identification showed that most of the victims had minor injuries, were male, aged  ≥ 34 years old, workers, and got into accidents in the afternoon. The conclusion was factors affecting the severity of traffic accident victims in Sidoarjo were head-on-collisions (hitting straight) and motorcycles as the vehicle type. Modelling obtained was 3,133 for the constant of head-on-collision (hitting straight), 1,464 for the constant of vehicle type (motorcycles), and Y value of 4,597. This study was not supported by complete predictor data, thus the data need to be added so that the accuracy of classification increases and the value gets significant.
KONDISI SANITASI PERALATAN DAN HIGIENE BAHAN MINUMAN TERHADAP KEBERADAAN BAKTERI Eschericia coli PADA ES TEH DI WARUNG KELURAHAN MULYOREJO, SURABAYA
Authors: Ningrum Lisa Fitria , Sulistyorini Lilis
Published: October 2021

Food stall is one of catering services that provide food/beverages for the public. The handling of utensils and selecting good food and beveragesarethe efforts to prevent the presence of Escherichia coli on food and beverages in thefood stalls. The studyaims to describe the process of handling the utensils, selecting food ingredients, and testing the presence of Escherichia coli in iced tea. The method of this research was cross-sectional with 34 unit samples of food stalls in Mulyorejo Urban Village. The samples were inserted in plastic and tested in the laboratory with the Escherichia coli parameter. The interviews were conducted with the food vendorsregarding the sources of clean water, the washing process, handling the utensils, and the iced tea ingredients, such as drinking water, tea, sugar, and ice cubes. The analysis was conductedin a descriptive approach. The results showed that 24% of the samples were positive containing Escherichia coli. The sellers’ primary source of clean water was derived from the the Water Company (PDAM)by 82.3%. Furthermore, 67.6% of the samples used detergent/soap in the washing processwith two buckets,used to dip the utensils repeatedly. In terms of storing the utensils, 94.1% of the the utensils were glassware stored face down. The ingredients of iced tea consisted of boiled water (50%), obtained from the well and the Water Company (PDAM), the tea ingredients which had been registered in food control agency, the sugar which was not spoiled or smelled, and the ice cubes which were bought from the neighborhood area (88.2%). It isproven that Escherichia coli existed inthe iced tea due to the sanitary components of utensils and the hygiene of beverage ingredients did not meet the requirements. It is recommended that the guidance can be given to the vendors, especially in washing the utensils correctly and selectingthe beverage ingredients, such as water and ice cubes.
MAYA INDEX DAN KEPADATAN LARVA AEDES AEGYPTI ANTARA DUSUN TEGALREJO DAN DUSUN KRAJAN KIDUL NANGGUNGAN PACITAN
Authors: Narmala Yelly Atiefsa , Azizah R.
Published: October 2021

Dengue fever remains a public health problem. Environmental factors influence the mosquito Aedes aegypti’s growth, especially if there are many containers in the neighborhood. The community of Nanggungan Village have a habit of storing water in containers, therefore, they risk to become breeding sites for mosquitoes. This study aims to identify the Maya Index status of Aedes aegypti between Tegalrejo and Krajan Kidul Village. The research was observational with a cross-sectional design. Total samples were 200 homes, which 100 homes from Tegalrejo and 100 homes from Krajan Kidul Village, taken by simple random sampling. The measurement of variables employed observation sheet and analyzed in a descriptive approach. The number of containers observed in the Tegalrejo Village was 394 units, and Karajan Kidul Village was 391 units. Maya Index statuses in Tegalrejo (92%) and Krajan Kidul Village (88%) were low. Maya Index status in Krajan Kidul (13%) was higher than Tegalrejo Village (8%). House Index (HI) in the Tegalrejo (18.0%) was lower than Krajan Kidul Village (25.0%), Container Index in Tegalrejo (5.30%) was lower than in Krajan Kidul Village (8.95%), Breteau Index in Tegalrejo (21.0%) was lower than in Krajan Kidul Village (35.0%), Density Figure in Tegalrejo and Krajan Kidul Village indicated a scale of 3 and 4. Based on the MI’s status, Tegalrejo and Krajan Kidul Village were included as a low-risk category of mosquito breeding sites. Based on the density number of larvae, two villages have a moderate risk of Dengue Fever transmission. The community should implement the Mosquitoes Breeding Sites Eradication Program (PSN 3M Plus) and minimize the presence of the containers.
Prediction of incompressible flows in a porous medium-free stream system
Authors: Polyakov Sergey Vladimirovich , Trapeznikova Marina Alexandrovna , Churbanov Alexander Georgievich , Churbanova Natalia Gennadievna
Published: October 2021

This paper deals with a model for coupled calculations of porous medium-free flow systems. It is based on the generalized Navier-Stokes equations obtained by averaging over a representative elementary volume of a porous medium and written for the entire computational domain consisting of two subdomains with different media. To implement numerically this model, a computational algorithm based on the finite element method for the coupled formulation of the equations for the momentum and continuity was developed by applying Newton's method. The verification of the developed calculation method was carried out on two verification cases using the known numerical results of other authors.
Integration of modern microprocessor technology of a distributed control system with AIS algorithms
Authors: Shiryayeva Olga , Samigulin Timur
Published: October 2021

The article forms the conditions for the integration of modern microprocessor technology that implements the laws of standard regulation in a distributed control system with such intelligent algorithms as artificial immune systems (AIS). Within the framework of the formed conditions, the problem of synthesis of the I-PD regulator for a two-circuit control system for the technological process of natural gas purification from various impurities of the distillation column is solved. Figs.: 4. Tabl.: 1. Refs.: 14 titles.
Method of synthesis of optimal grip trajectories of a manipulator of an autonomous mobile robot
Authors: Ashepkova Natalja , Koshevoy Nicolay
Published: October 2021

The features of the dynamics of an autonomous mobile robot of variable configuration with a relative motion of the manipulator are considered.
To effectively perform technological operations by the AMR manipulator in extreme previously unknown conditions, it is advisable at the design stage to develop a database containing the optimal sequences of movements along generalized coordinates that ensure the movement of the gripper between the given initial and final points of the working space. Figs.: 3. Tabl.: 2. Refs.: 20 titles.
La edad de la población en la COVID-19: controversias socio-demográficas sobre un hecho común
Authors: Rodríguez Vicente
Published: October 2021

La pandemia COVID-19 ha traído consigo múltiples incertidumbres que afectan al individuo, a la sociedad y a los territorios, pero también una certeza poderosa, son las personas mayores quienes tienen una posición más vulnerable ante la COVID-19. La identificación de esta población sigue criterios biológicos, cronológico/ estadísticos, instrumentales o de decisión social y política, que hace posible su análisis poblacional y su uso en la definición de políticas públicas a distintos niveles. La abundante bibliografía generada durante la pandemia permitirá, mediante el análisis del contenido cualitativo a través de Atlas.ti, valorar las controversias sobre la edad de la población. La situación de partida es que los documentos estudiados son muy diversos, producidos con criterios de urgencia, sin seguir siempre los procedimientos de validación en la toma de datos, en el uso de métodos y en el contraste de evidencias. Muestran las controversias en su denominación, en la imagen que tiene la sociedad y los medios de comunicación, en las valoraciones éticas de cómo la población mayor es tratada, en la consideración de la edad para las recomendaciones sanitarias y profesionales, y en, por último, su significación en las medidas políticas en marcha durante la pandemia.
A Multi-Hazard Historical Catalogue for the City-Island-State of Malta (Central Mediterranean)
Authors: Main Geoff , Gauci Ritienne , Schembri John , Chester David
Published: October 2021

The city-island-state of Malta is traditionally viewed as a low-hazard country with the lack of a long historical catalogue of extreme events and their impacts acting as an obstacle to formulating evidence-based policies of disaster risk reduction. In this paper, we present the first multi-hazard historical catalogue for Malta which extends from the Miocene to 2019 CE. Drawing on over 3,500 documents and points of reference, including historical documentary data, official records and social media posts, we identify at least 1,526 hazard events which collectively have caused the loss of at least 661 lives. Recognising that historical materials relating to Malta are complicated by the presence of a strong temporal bias, we establish a four-point reliability indicator and apply this to each of the 1,062 recordings, with the result that some 78 % show a high degree of reliability. For an island state where there are significant gaps in the knowledge and understanding of the environmental extremes and their impacts over time, this paper addresses and fills these gaps in order to inform the development of public-facing and evidence-based policies of disaster risk reduction in Malta.
Cutaneous adverse reactions of COVID-19 vaccines: a systematic review
Authors: Shamsabadi Ahmadreza , Golezar Mohammad Hossein , Mardani Abbas , Mallah Manthar Ali , Golezar Samira , Moradi Bagher , Qaderi Kowsar
Published: October 2021

Background: Numerous vaccines are implementation for the prevention of severe course and lethal outcome of coronavirus disease 2019 (COVID-19).Objective: This systematic review aims to summarize and integrated the findings of studies regarding cutaneous side effects of COVID-19 vaccines. Methods: This systematic review conducted by searching the scientific databases of PubMed, Scopus, Science direct, and Web of knowledge from the beginning of the COVID-19 to10/5/2021. Articles were reviewed and analyzed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist.Results: Seventeen studies were included after the screening of search results based on to the eligibility criteria. The results showed that injection site reactions and delayed large local reactions were the most common side effects arising from all vaccine types. Most cutaneous reactions occurred in middle-aged women, after the first dose of vaccine, and 1-21 days after vaccination. Most cutaneous reactions were self-limiting, need little or no therapeutic intervention, and were not regarded as a barrier to injecting a second dose.Limitations:Conclusion: In certain groups such as patients with allergies and a history of local injection reactions, pre-vaccination counseling and the use of appropriate medications may be helpful. However, more studies are needed to investigate the side effect profile of all COVID-19 vaccines.
Biodegradation of Polypropylene By Pseudomonas Aeruginosaisolated From Wastewater Associated Soil; A Potential Method To Eliminate The Plastic Pollution To Save Ecosystem
Authors: Selvakumar Vijayalakshmi , Gopalsamy Preethi , Muthusamy Karnan , Manivel Thenmozhi , Chelliah Ramachandran , Sundarraj Dinesh Kumar , Narayanan Sathammai Priya , Oh Deog-Hwan
Published: October 2021

The face mask introduction in SARS-CoV-2 pandemic situation, one of the precautionary measure to reduce the rate of transmission of infection from person to person. There are many type of of face masks enter into our global market with various size and designs. Among those, surgical mask belongs to secure an important place and this aimed to evaluate the degrading efficiency disposable face masks (single use face masks). The present study dealt with, biodegradation of face masks which is made of polypropylene with the help of bacterial strainPesudomonasaeruginosaisolated from the plastic waste dumping sites in an around the Tiruchirappalli, India. The bacteriacould degrade PP mask via the formation of biofilm on a solid medium. To degrade the PP, the mask pieces were incubated with the culture of P. aeruginosain three different solid and liquid medium (nutrient agar, Bushnell Haas agar and mineral salt medium) for 30 days at 37ᵒC. The microbial degradation(up to 33% of weight reduction of PP films within 30 days) was proved by surface changes along with the variation in the intensity of functional groups as well as carbonyl index variations using Field-Emission Scanning Electron Microscopy (FE-SEM) and Fourier Transform Infra-Red Spectroscopy (FTIR) analysis. These results suggested that P.aeruginosa strain can prove to be a suitable candidate for polypropylene mask biodegradation without causing any impairment to our health or environment.
Simulation as a Training Tool in Retina Training in Latin America (SIMRET Project): Survey (Report Nº 1)
Authors: Luciano Andreas Di , Montero María , Calisse Alana , Emiliozzini Nicolás , Oetting Thomas , Ferris John
Published: October 2021

Purpose: To evaluate the situation in Latin America regarding the use of simulation as surgical training in the retina.Methods: An online survey was carried out to determine the resources available in simulated retinal training in Latin America. The survey was shared via email to retina fellows and subspecialists in Latin America between November 2020 and March 2021. The relevant resources for retinal subspecialty surgical training were: biological material (pig / goat eyes); artificial eyes, and virtual reality devices. The survey was divided into five sections: (1) Identification of participants (2) Availability of resources in retinal simulation (3) Types of available resources and types of practice techniques (4) Reliability of resources according to their personal experience (5) Reasons why this type of training is implemented or not. Results: 190 participants were surveyed. The overall response rate was 61.05 %. 96 (82.8%) of the 116 responding did not have access to a retinal simulation training program. Of the 20/116 that did have access (17.2%), the most frequent resource available was biological eyes 32/116 (27.6%), followed by artificial eyes 16/116 (14.0%), and virtual reality devices 15/116 (13.0%). The reasons for lack of simulation resources was economic (77.1%), followed by the lack of a physical space (17.1 %), and interestingly some participants (5.2%) reported that it did not seem necessary to use simulation to develop new surgical skills.Conclusions: Our work highlights the lack of resources for surgical training in the retina using simulation in Latin America.
Proof of Einstein's Postulates
Authors: Golovkin Boris
Published: October 2021

Based on the assumption that the experiment confirms the STR, it is
shown that the magnitude of the speed of light is an extremely slowly decreasing
function of its frequency. However, at frequencies less than 1 hertz, the speed
light begins to decrease sharply, and at a frequency of 4,6∙〖10〗^(-21) с-1, the speed
of light becomes zero. Such light could serve as the Absolute Reference System,
but due to their negligible mass, they do not have any effect on the processes
taking place. This explains the postulate of Einstein's principle of relativity. The
formulas for the change in the speed and frequency of light during the transition
from one IRS to another remain unchanged, which proves Einstein's postulate of
the constancy of the speed of light in any IRS.
Advanced Protection Scheme For Information Monitoring in Internet of Things Environment
Authors: Gaber Mohamed , Khalaf Ashraf , Mahmoud Imbaby , El_Tokhy Mohamed
Published: October 2021

In the recent years, Internet of Things (IoT) technologies are growing to make great progress for the nuclear energy applications. The protection of their sensitive information has become an important challenge in implementing secure application services. These services should meet the major security attributes including confidentiality, availability, and integrity. This paper introduces a security scheme for the transmitted sensitive information and secure monitoring of the critical radiation levels at the nuclear facilities. It evaluated through integrating the cryptography and steganography techniques with cloud computing services. The cryptography techniques based on Advanced Encryption Standard (AES) and Rivest, Shamir-Adleman (RSA) algorithms. The scheme uses the extracted cryptography keys from authenticated biometric attributes. The proposed scheme provides a low computational time suitable for fast responding in the emergencies. It allows securing access for the encrypted sensitive measurements, files, and images with high data integrity and confidentiality. Furthermore, it hides the confidential sensitive information with great capacity and imperceptibility through the transmitted carrier image. The security performance analysis ensures the robustness of introducing scheme against various attacks through authentication, encryption, and information hiding techniques. It resists the serious attacks, including the man in the middle, noise, and Distributed Denial of Service (DDOS) attacks.
Fixed Point Result in Controlled Fuzzy Metric Spaces with Application to Dynamic Market Equilibrium
Authors: Tiwari Rakesh , rakocevic vladimir , Rajput Shraddha
Published: October 2021

In this paper, inspired by the work of Muzeyyen Sangurlu Sezen [22] and H. Saleh Nasr et al. [20], we introduce ʘf -type controlled fuzzy metric spaces and establish some  fixed point results in controlled fuzzy metric spaces. We provide suitable examples to validate our result. We also employ an application to substantiate the utility of our established result for  fiding the unique solution of an integral equation emerging in the dynamic market equilibrium aspects to economics.Subject Classification: 54H25, 47H10, A11.
A Secured Storage and Communication System for Cloud Using ECC, Polynomial Congruence and DSA
Authors: J Nithisha , P Jesu Jayarin
Published: October 2021

Security is necessary today’s fast computer world during the data communications in internet and cloud environment. The cloud security is becoming very challenging task today due to the presence of huge volume of cloud users. Even though, various cloud secured storage mechanisms are available and tried to fulfill the current requirement. However, not yet fulfill the cloud user’s requirements in terms of security while storing and sharing the data in cloud. For this purpose, this work proposes a new secured storage and communication system for providing data security while storing the data in cloud database and sharing the data between the cloud users in cloud. This system consists of three different algorithms for performing prime number generation, digital signature creation for generating keys, encryption, decryption and authorization. In this paper, we propose a new technique to find a co-prime number which is used to generate keys in key generation process and also useful for performing encryption and decryption process. Moreover, a new key generation technique is also introduced for ECC and DSA using polynomial congruence for performing key generation process securely. In addition, a new Elliptic Curve and Polynomial Congruence based Encryption / Decryption algorithms for performing data encryption and decryption in the process of data storage and communication. Finally, the user authenticity is verified by the proposed digital signature algorithm in this work. The experiments have been conducted for evaluating the proposed secured storage and communication system and proved as better than others in terms of efficiency and security level.
Detecting Impacts of Surface Development Near Weather Stations Since 1895 in the San Joaquin Valley of California
Authors: Kim Diane , Christy John R.
Published: October 2021

Temperature readings observed at surface weather stations have been used for detecting changes in climate due to their long period of observations. The most common temperature metrics recorded are the daily maximum (TMax) and minimum (TMin) extremes. Unfortunately, influences besides background climate variations impact these measurements such as changes in (1) instruments, (2) location, (3) time-of-observation and (4) the surrounding artifacts of human civilization (buildings, farms, streets, etc.) Quantifying (4) is difficult because the surrounding infrastructure, unique to each site, often changes slowly and variably and is thus resistant to general algorithms for adjustment. We explore a direct method of detecting this impact by comparing a single station that experienced significant development from 1895 to 2019, and especially since 1970, relative to several other stations with lesser degrees of such development (after adjustments for the (1) to (3) are applied.) The target station is Fresno, California (metro population ~15,000 in 1900 and ~1 million in 2019) situated on the eastern side of the broad, flat San Joaquin Valley in which several other stations reside. A unique component of this study is the use of pentad (5-day averages) as the test metric. Results indicate that Fresno experienced +0.4 °C decade -1 more nighttime warming (TMin) since 1970 than its neighbors – a time when population grew almost 300%. There was little difference seen in TMax trends between Fresno and non-Fresno stations since 1895 with TMax trends being near zero. A case is made for the use of TMax as the preferred climate metric relative to TMin for a variety of physical reasons. Additionally, temperatures measured at systematic times of the day (i.e. hourly) show promise as climate indicators as compared with TMax and especially TMin (and thus TAvg) due to several complicating factors involved with daily extreme measurements.
Mathematical Modeling of Landslide Slope Dynamics and Sustainable Development of Territories of Asian Russia
Authors: Khoroshilov Valery S. , Karpik Alexander P. , Musikhin Igor A.
Published: October 2021

The possibilities of applying the results of modeling the landslide stress-strain state to predict landslide hazard and make management decisions under intensive and spatial development of the territories of Asian Russia are considered. Economic and spatial development of the territories concerning reorganization or formation of economically viable components of various production chains require careful consideration of their safe and continuous operation. In this respect, great attention is paid to the studies on exogenous geological processes under the complex geomorphic conditions that can have a substantial impact on the operation of production chain links. The authors present a technique for modeling a landslide slope movement caused by anthropogenic impact. The revealed patterns in which influencing factors affect vertical displacements of landslide points created the conditions for their description at a new qualitative level. Mathematical modeling of landslide slope movement is based on the dynamic-type prediction model. This made it possible to predict the displacements of observed landslide points with sufficient accuracy. Based on a geo-cognitive safety monitoring of production chain links primarily important for the social and economic development of territories, the possibility of using the prediction models of the landslide slope stress-strain behavior as a "solver" in expert systems for forecasting landslide danger when making management decisions is shown.
Pre-exposures of Aerosolized Polyvalent Bacterial Lysates Protect Against Bleomycin-Induced Pulmonary Fibrosis in Mice - An Exploratory Study
Authors: Zhu Xiaoling , Yuan Shan , Zheng Xiaofang , Wang Xiaorong , Zhang Jinnong
Published: October 2021

RationaleIdiopathic pulmonary fibrosis (IPF) is a chronic fibrosing interstitial pneumonia of unknown cause, no therapeutic modalities could reverse or stop its ever deteriorating course. It has been found that stimulation of lung innate immunity using bacterial lysates protected against lethal pulmonary infection, we speculate it may also protect against the development of pulmonary fibrosis.MethodsC57BL/6 mice were exposed to an aerosolized mixture of polyvalent bacterial lysates (PVBLs) or phosphate-buffered saline (PBS, as control) three times on separate day, thereafter the lungs were intratracheally infused of Bleomycin (BLM). Pulmonary morphology, Ashcroft’s scale of pulmonary fibrosis and pro-inflammatory cytokines such as interferon (IFN)-γ and interleukin (IL)-4 were evaluated 14 days later.ResultsExposures of PVBLs did not induce any discernible structural abnormalities in the lung, while the ratio of IFN-γ/IL-4 was increased (P < 0.05); BLM-induced pulmonary fibrosis was associated with an overwhelming down-regulation of IFN-γ and IL-4 (P < 0.01) ; In comparison with the controls, pre-exposures of the PVBLs protected against BLM-induced pulmonary fibrosis, that was demonstrated by a greater reduction of Ashcroft’s fibrotic score [median (95%CI): 3.94 (3.33–4.56) vs. 3.04 (2.55–3.52), P < 0.05] and a greater decrease of hydroxyproline (0.93 ± 0.16 vs. 0.64 ± 0.18, g/mg, P < 0.01) as well. Though the PBVLs pre-exposures did not restore the BLM-induced down-regulation of IL-4 and IFN-γ, the ratio of IFN-γ/IL-4 maintained greater than that in the controls (2.25 ± 0.70 vs. 0.78 ± 0.33, P < 0.01). ConclusionsBLM-induced murine pulmonary fibrosis is associated with an overwhelming down-regulation of IFN-γ and IL-4. Pre-exposures of the aerosolized PVBLs protect against the BLM-induced pulmonary fibrosis.
Protocol for a Cluster Randomized Trial To Evaluate The Effectiveness of Intervention On Myopia (The ES-SCI Study Intervention Section)
Authors: Zhang Xiyan , Yang Jie , Ma Jun , Tao Fangbiao , Pan Chen-Wei , Wang Yan , Yang Wenyi , Xiang Yao , Wang Xin , Zhang Fengyun , Du Wei
Published: October 2021

Background: Myopia is commonly observed among Chinese students aged 6-18 years.Objectives: To describe the protocol of the cluster-randomized trial to determine and evaluate the effectiveness and economic burden of multi-technology route intervention on myopia among eastern Chinese students. Methods：A cluster-randomized trial will be conducted to test the effectiveness of an intervention to prevent the progression or onset of myopia. The effectiveness evaluation will be tested in comparison with the control group. The participating students will be assessed at baseline and 3-,6-.9-.12-,24-,36-,48-,60-months follow up.Discussions: Eastern Chinses Student common disease Surveillance Cohort and Intervention study is designed to provide accurate epidemiological clues and precise prevention strategies for school-age students. This study is a large sample and long-term follow-up cluster randomized controlled trial in eastern China. The intervention population is students aged 7.5-9.5. This study aims to provide an evidence-based basis for the intervention of myopia among Chinese students and provide the theoretical basis for the effect evaluation.Trial registration: ChiCTR2100051064. Registered on 11 Sep 2021.
The Optical Biometric Measurements In Patients With Previously Received Covid-19 Treatment
Authors: Çetinkaya Tuğba , Kurt Muhammed Mustafa
Published: October 2021

Purpose: To determine the comparison of the optical biometric measurements using optical biometry in patients with previously received COVID-19 treatment and the control group.Methods: In this cross-sectional study, the COVID-19 was diagnosed by polymerase chain reaction test, clinical signs and radiologic findings. Patients with previously received COVID-19 treatment was determined as COVID-19 group and the age and sex-matched healthy subjects were served as control group. The optical biometric measurements including corneal astigmatism, keratometry, astigmatic axis, central corneal thickness, anterior chamber depth and axial length were obtained using Nidek optical biometry (AL-Scan; Nidek Co., Ltd., Japan).Results: The measurements of keratometry(p=0,47), corneal astigmatism(p=0,42), axial length(p=0,78), anterior chamber depth(p=0,46) and central corneal thickness(p=0,43) were similar between the COVID-19 and control groups. The astigmatic axis type taken from 2.4 mm of the cornea showed statistically significant difference between two groups (p=0,01), while the measurements taken from 3 mm of the cornea were similar(p=0,15). In the subgroup analysis, axial lenght, anterior chamber depth and central corneal thickness measurements were found statistically significantly higher in the male gender of the COVID-19 group (p= 0,03; p= 0,01; p=0,03, Mann Whitney U).Conclusion: Changing in the optical biometric measurements can be seen as a result of the fact that COVID-19 is more frequent and severe in male gender and SARS-CoV-2 can attach to the cornea via ACE-2 receptors. To our knowledge, there is no study about this subject yet and conducting research with other studies on this issue will provide a better enlightenment about this subject.
Use of Serum Drug Concentration Monitoring During the Treatment of Severe Rifampicin and Ethambutol Poisoning: A Case Report
Authors: Gao Wenying , Chen Ye , Fu Jiapeng , Liu Zhichao , Wang Jinghua , Ning Xianjia , Ke Xue , Li Guobao
Published: October 2021

Background: Despite rifampicin and ethambutol being widely used to treat patients with tuberculosis, reports of potentially lethal overdoses of these drugs are rare. The toxic effects of rifampicin become apparent at doses of 9–12 g, and become potentially fatal at doses over 14 g. Case presentation: We describe a case of severe rifampicin (18 g) and ethambutol (25 g) poisoning that was successfully managed using hemoperfusion (HP) and hemodiafiltration (HDF) in conjunction with serum blood drug concentration monitoring. A 57-year-old female was rushed to the emergency room of Shenzhen Third People's Hospital (China) 4 hours after she ingested 120 tablets of rifampicin (18 g) and 100 tablets of ethambutol (25 g). After emergency symptom treatment, she was transferred to a ward where she presented in an irritable state, with orange–red skin and mucus membrane discoloration and slight yellowing of the sclera. The patient’s serum levels of rifampicin (177.2 mg/L), desacetylrifampicin (194.40 mg/L), and ethambutol (13.44 mg/L) were determined. After three cycles of HP and HDF, her serum drug levels had declined to within a normal range, and the color of her skin and mucosa gradually returned to normal. She was discharged from the hospital after a 4-day stay. Ten days after discharge, her follow-up bloodwork indicated normal liver and kidney functioning. Conclusions: HDF and HP are effective at clearing toxic levels of rifampicin. Serum drug concentration monitoring helps accurately guide drug poisoning treatment.
Occurrence,Distribution and Risk Assessment of Five Kinds of Antibiotics in Mattress on Swine Farm use Ectopic Fermentation Systems in Zhejiang Province
Authors: wei Zhou , decheng suo , fan xia , xiao zhiming , Zhang hangjun , Zhou zhijin , Huo xuan , Chong yang
Published: October 2021

Mattress is among the main products of ectopic fermentation system (EFS),however, the research on the data of antibiotic residues in the mattress of EFS and risk assessments of mattress have not been conducted. This study involved a scale survey to assess the levels and distributions of 54 antibiotics residues, including 4 tetracyclines, 19 quinolones, 22 sulfonamides, 3 amphenicols, and 6 macrolides in mattress on 12 swine farm that uses ectopic fermentation systems (EFS) in Zhejiang Province. A total of 25 antibiotics were detected in mattress, and the total residue amount of antibiotics in mattress samples of each farm was 0.77–28.2 g/T. Chlortetracycline had the highest contribution rate, and the residue amount of antibiotics in mattress is not entirely determined by the start-up time of EFS but is related to the use of feed containing antibiotics, medication habits, the level of mattress management, and maintenance methods of EFS. The risk assessments of antibiotics in the mattress were carried out. The results show low risk for soil on swine farm that uses EFS.
Association of the Trajectories of Metabolic Component and Outcomes in Patients with Chronic Kidney Disease: The National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) Study
Authors: Huh Hyuk , Song Je Hun , Kim Yunmi , Kim Gwang Sil , Koo Hoseok , Yoo Kyung Don , Lee Jong Soo
Published: October 2021

Background: Chronic kidney disease (CKD) could cause and exacerbate metabolic disturbances, including hypertension and dyslipidemia. Conversely, metabolic disturbances affect renal outcome and mortality in CKD patients. However, studies on the relationship between the pattern of metabolic disturbance and prognosis in CKD during the observation period are lacking.Methods: Through trajectory analysis, we found that subjects with CKD were divided into two groups in a pattern of metabolic disturbances over time. Subjects were divided into low (A) and high (B) groups using K-means clustering based blood pressure, total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL) cholesterol measurement at two time-points. The optimal number of clustering was selected using the Calinski-Harabasz index. The outcome of our study was a decline in renal function and mortality.Results: This study is a large-scale retrospective study of 51,313 subjects with CKD from The National Health Insurance Service-National Health Screening Cohort. The mean age of the subjects was 65.7±9.7 years, and 50.4% were male. During the study period, the mean systolic blood pressure (SBP) was 127.8±15.8 mmHg and diastolic blood pressure (DBP) was maintained at 83.6±8.4 mmHg. Mean serum LDL cholesterol and TG levels were 196.4±40.9 and 147.1±89.8 mg/dL, respectively After clustering, the low group (A group) had the mean SBP of 118.9±10.9mmHg and a TG of 118.8±46.1 mg/dl. However, in the high group (B group), it was found that the mean SBP was maintained at 138.9 ± 13.2 mmHg, and the TG was maintained at was 266.1 ± 116.7 mg/dL. In logistic regression analysis, the high group of SBP was associated with the decline of renal function and increased mortality (odds ratios [OR] 1.13 95%confidence intervals (CI) 1.066-1.212). and the high group of TG was independently associated with a decrease in renal function (OR 1.15, 95% CI 1.069-1.240). Conclusion: The results of this study showed the association of the pattern of metabolic disturbances with the prognosis of CKD over time. Additionally, it could be useful to control intensively SBP for renal outcome and mortality in CKD, and management of high TG could be necessary to improve renal outcome.
Bayesian Multilevel Analysis of Children Vaccination Coverage in Ethiopia
Authors: Kitabo Cheru Atsmegiorgis , Bekele Adugna
Published: October 2021

Background: Vaccine preventable diseases (VPDs) account for 17% of the global under-five mortality per annum and more than half of these deaths have occurred in sub-Saharan Africa. Ethiopia is one of the ten countries which account for about 62% of unprotected children and one of the three countries (Ethiopia, Nigeria, and the Democratic Republic of Congo) in which half of the world’s child deaths have occurred are in sub-Saharan Africa. The main objective of this study is to understand the current status of complete immunization coverage and examine its determinant factors among children in Ethiopia.Method: Bayesian multilevel logistic regression models have been utilized to realize the objectives of the research. The dataset used for this study comes from the 2016 Ethiopian Demographic and Health Survey (EDHS). The convergences of parameters are checked by using Markov chain Monte-Carlo (MCMC) using SPSS and MLwiN software. Results: The descriptive result revealed that, out of the 1929 children who are supposed to complete all basic childhood vaccines, 699 (36.2%) children were completely vaccinated, while 1230 (63.8%) children were incompletely vaccinated. Moreover, regions Afar, Somali and Gambela have the least proportion of vaccination coverage. Among the multilevel models, Bayesian random coefficient model is found to be a better model to estimate the vaccination coverage of children. Using this model, it has been found that factors like place of residence, maternal educational, mother occupation type, Antenatal Care (ANC) utilization, Postnatal Care (PNC) utilization, type of pregnancy, household wealth index, and field worker visit were found to be the significant factors that influences the vaccination coverage. Conclusion: In general, it has been estimated that the vaccination coverage in the country is relatively low and there was significant variation in the level of vaccination coverage in regions of the country.
Sustainable Environmental Management System in Food Crop Agriculture in Wonosobo District, Indonesia
Authors: Yusianto Rindra , Suprihatin Suprihatin , Hardjomidjojo Hartrisari , Marimin Marimin
Published: October 2021

The sustainability level needs to be measured and analyzed comprehensively using a representative measurement model. The main objective of this study was to develop a sustainable environmental management system for food crop agriculture. The proposed hybrid measurement model integrates the inventory of greenhouse gas (GHG) effects and geographic information systems (GIS) with the Internet of Things (IoT). The proposed model was implemented in a potato farming system in six sub-districts in Wonosobo, Indonesia. From an environmental perspective, that is, methane (CH4), carbon dioxide (CO2), and nitrous oxide (N2O), emissions were measured using the Raspberry Pi. Then, we added GHG spatial mapping by considering the environmental quality index. Sustainability levels were classified into three classes. We then measured the economic viability, social acceptance, and spatial perspective index (Si). The results showed that the value of sustainability was >0.1 without considering Si, meaning that all samples showed conditions above the threshold for sustainability. However, after adding Si, namely altitude, slope, soil texture, temperature, and rainfall, the N1 and N2 samples had values >0.1. In contrast, N4 and N6 showed values <0.1. The proposed model can measure and analyze the sustainability of a sustainable food crop system. This model has also successfully proposed a strategy by increasing environmental sustainability in the Garung sub-district using the ANP Super Decision. We propose an alternative strategy: government regulation, strengthening agricultural institutions, disseminating emissions and environmental aspects, and academic assistance. In future research, this model can be used to control CH4, CO2, and N2O emissions.
Prevalence of Oral Mucosal Lesions in Children in Rural Yunnan, China: a Population-based Study
Authors: Yao Hui , Song Qianqian , Zhang Qiongyue , Tang Guoyao , Liu Mingshan
Published: October 2021

Background: This population-based cross-sectional study aimed to evaluate the prevalence of oral mucosal lesions (OMLs) in children in a rural area in China as epidemiological data on these conditions from such areas are insufficient. Methods: A total of 3145 children in rural Yunnan were enrolled. A socio-economic questionnaire and a field survey of OMLs were administered. We gathered information on factors (sex, age, caregiver, parental education, and last-month household income) that might be associated with OMLs in these children.Results: OMLs in children in rural Yunnan had a prevalence of 1.8% (95% CI; 1.3–2.3%). The most prevalent OML was oral ulcer (n=11; 18.3%), followed by linea alba (n=10; 16.7%), whereas the least prevalent OMLs were frenal tag (n=1; 1.7%) and herpetic infection (n=1; 1.7%). On unadjusted or adjusted regression, school-aged children had about 50% lower risk of OMLs than preschoolers.Conclusions: These findings indicate that the prevalence of OMLs in rural Yunnan is lower than previously reported. Additionally, age might be associated with the risk of OMLs in children in rural Yunnan.