bluuebunny/crossref_metadata_2025 huggingface dataset:
A preliminary chronological study to understand the construction phases of a Late Copper–Early Bronze Age kurgan (kunhalom)
Authors: Szilágyi Gábor , Náfrádi Katalin , Sümegi Pál
Published: January 2019

The aim of this study is to identify the milestones of landscape evolution around the Ecse Mound (Karcag-Kunmadaras, Hortobágy National Park, Hungary) in the Holocene period by sedimentological and malacological analysis of strata underneath and within the body of the kurgan concerned, including that of the same characteristics of the artificially piled layers. An undisturbed core drilling was carried out and the sedimentological properties of both the mound and of the substrate baserock were revealed, analysis of which has been supported by three radiocarbon (AMS) measurements. The baserock formation during the last phase of the Ice Age, Middle and Upper Pleniglacial, and Late Glacial phases was followed by soil development in the Holocene, while the mound was constructed in two phases at the end of the Copper Age by the communities of the Pit Grave (Yamna or Ochre Grave) Culture. By publishing these preliminary data, it is also intended to draw attention to the need of focused research efforts by standardized methodology in kurgan research, in order to make the results of different studies consistent and comparable.
PLEIOTROPIC EFFECTS OF SIMVASTATIN AND FENOFIBRATE IN PATIENTS WITH RHEUMATOID ARTHRITIS: A COMPARATIVE STUDY
Authors: Shirinsky I. V. , Kalinovskaya N. Yu. , Shirinsky V. S.
Published: January 2019

We compared clinical efficacy and safety of simvastatin (40 mg daily) for 12 weeks (n = 33, group 1) vs fenofibrate (145 mg daily) for 12 weeks (n = 33, group 2) in patients with active RA taking stable doses of DMARDs. Changes in the Disease Activity Score (DAS28) with 28 joints count was the primary endpoint. Both simvastatin and fenofibrate treatment resulted in statistically significant decrease in DAS28 scores, the patients taking fenofibrate developed moderate EULAR and ACR20 responses 1.5 times more frequently than the patients taking simvastatin. There were no serious adverse events in either group. Clinical response was associated with pleiotropic effects, both in simvastatin- and fenofibrate-treated groups. Both drugs resulted in decrease of atherosclerosis immunological markers (CRP and IL-6 levels). At the end of treatment, we observed a decrease in serum IL-17 in patients taking simvastatin. No changes in serum IL-8, TNFα, and IFNγ were observed in both groups. The total cholesterol concentrations did not change, whereas simvastatin treatment resulted in decreased serum LDL cholesterol, while increasing serum HDL cholesterol levels. There was a decrease of triglyceride concentrations in patients taking fenofibrate. In conclusion, simvastatin and fenofibrate can be considered as drugs of choice in RA patients with high risk of atherosclerosis who do not respond to conventional DMARDs. There is a need for larger comparative studies, in order to define detailed guidelines for their use.
Aromatase Inhibitors and Newly Developed Nonalcoholic Fatty Liver Disease in Postmenopausal Patients with Early Breast Cancer: A Propensity Score-Matched Cohort Study
Authors: Lee Jung Il , Yu Jung-Hwan , Anh Sung Gwe , Lee Hyun Woong , Jeong Joon , Lee Kwan Sik
Published: January 2019

Background

Unlike tamoxifen, the relationship between aromatase inhibitor use in postmenopausal patients with breast cancer and nonalcoholic fatty liver disease (NAFLD) has not been delineated.

Materials and Methods

A retrospective analysis of 253 patients with early breast cancer without baseline NAFLD and treated with nonsteroidal aromatase inhibitors was performed. Among them, 220 patients were matched for sex, age, and menstruation status with healthy patients, and the prevalence of NAFLD was compared. NAFLD was determined by hepatic steatosis index in the absence of other known liver diseases. The presence of significant liver fibrosis in patients with NAFLD was determined noninvasively by AST-platelet ratio index, FIB-4 score, and NAFLD fibrosis score (NFS).

Results

Postmenopausal patients with breast cancer undergoing treatment with aromatase inhibitors had higher prevalence of NAFLD independent of body mass index (BMI) and underlying diabetes mellitus (DM). Although the aromatase inhibitor group showed higher fibrotic burden by NFS, independent of BMI and DM, the proportion of advanced fibrosis did not show statistically significant differences between AI-treated patients and the healthy patients. Those with abnormal baseline fasting glucose levels are suggested to have increased risk of NAFLD development after aromatase inhibitor treatment. In addition, patients with NAFLD developed after aromatase inhibitor use had significantly lower disease-free survival than those without NAFLD, although there was no significant difference in overall survival.

Conclusion

Results of this study suggest that inhibition of estrogen synthesis in postmenopausal women undergoing treatment with aromatase inhibitors could increase the risk of NAFLD, which might have some influence on the prognosis of patients with breast cancer.
Everolimus plus Exemestane for Hormone Receptor-Positive Advanced Breast Cancer: A PAM50 Intrinsic Subtype Analysis of BOLERO-2
Authors: Prat Aleix , Brase Jan Christoph , Cheng Yuan , Nuciforo Paolo , Paré Laia , Pascual Tomás , Martínez Débora , Galván Patricia , Vidal Maria , Adamo Barbara , Hortobagyi Gabriel N. , Baselga José , Ciruelos Eva
Published: January 2019

Background

The prognostic and predictive value of the two nonluminal (human epidermal growth factor receptor 2 [HER2]-enriched and basal-like) subtypes within advanced hormone receptor-positive (HR+) breast cancer is currently unknown.

Materials and Methods

This study retrospectively analyzed 261 tumors (80.7% primary; 19.3% metastatic) from the BOLERO-2 study; BOLERO-2 randomized 724 patients with advanced HR+/HER2-negative breast cancer to everolimus plus exemestane or placebo plus exemestane. Tumors were classified using a PAM50 subtype predictor. Multivariable Cox regression analyses tested the independent prognostic significance of PAM50, and associations between PAM50 subtypes and treatment upon progression-free survival (PFS) were evaluated.

Results

Subtype distribution was 46.7% luminal A (n = 122), 21.5% HER2-enriched (n = 56), 15.7% luminal B (n = 41), 14.2% normal-like (n = 37), and 1.9% basal-like (n = 5); HER2-enriched subtypes were more common in metastatic versus primary tumors (32.0% vs. 18.7%; p = .038). Median PFS differences between luminal and nonluminal (6.7 vs. 5.2 months; adjusted hazard ratio, 0.66; 95% confidence interval [CI], 0.47–0.94; p = .020) and HER2-enriched and non-HER2-enriched subtypes (5.2 vs. 6.2 months; adjusted hazard ratio, 1.53; 95% CI, 1.07–2.19; p = .019) were significant. Everolimus plus exemestane significantly improved median PFS versus placebo plus exemestane among patients with HER2-enriched tumors (5.8 vs. 4.1 months; adjusted hazard ratio, 0.49; 95% CI, 0.26–0.90; p = .034); however, the association between HER2-enriched tumors and everolimus benefit was nonsignificant (p = .433).

Conclusion

The HER2-enriched subtype was identified in a substantial proportion of advanced HR+/HER2-negative breast tumors, and was a consistent biomarker of poor prognosis. Tailored therapies are therefore needed for HER2-enriched tumors in the advanced HR+/HER2-negative breast cancer setting.
Local scour depth at a bridge pier protected by a collar in steady and unsteady flow
Authors: Karimaei Tabarestani Mojtaba , Zarrati Amir Reza
Published: January 2019

Scour hole development around a circular bridge pier protected by a collar under steady and unsteady flow conditions is thoroughly investigated. At the first stage, formation of a scour hole around the collar under different steady flow conditions was studied. Results showed that flow intensity, which is defined as upstream undisturbed bed shear velocity divided by bed material critical shear velocity (u*/u*c), is the major factor affecting collar efficiency in postponing scour depth at the pier nose. Decreasing u*/u*c from 0·99 to 0·8 increased the time taken to undermine the collar by about 26 times. At the second stage, formation of a scour hole around the collar under different hydrographs was studied. The range of u*/u*c in a hydrograph and its characteristics were found to be the most important factors for collar efficiency. Finally, empirical equations were developed to calculate the time taken to undermine the collar and for scour depth development.
MİDHAT CEMAL KUNTAY’IN GARB’A TENKİTLERİ: İFTİRA-YI TAASSUB
Authors: GÜNER Selda
Published: January 2019

Bu makale, Mithat Cemal Kuntay’ın az bilinen ve dolayısıyla yeni
harflerle yayınlanmamış ve bir Batı tenkidi olan 1911 tarihli İftira-yı Taasub eserinin, takdim ve
teşhirini yapmayı amaçlamaktadır. Ayrıca Osmanlıca yazılmış olan bu risale
bugünkü Türkçe’ye aktarılacaktır. Midhat Cemal’in henüz 28 yaşında iken  yazdığı bu risale, yaşlı imparatorluğun genç
kalemlerinden birinin imzasını taşımaktadır. Diğer yandan bu çalışma, metnin
özerkliğini de dikkate alacak ve fakat yazar ve metnin öznelliklerinin muayyen
bir tarihselliğin sınırları tarafından oluşturulduğunu ihmal etmeyecektir.
Öncelikle Midhat Cemal’in Türk edebiyatı tarihindeki yeri, onun şahsi
özellikleri de hesaba katılarak anlatılacaktır. Onun milli hislerini eserlerine
yansıtması belirgin bir özelliğidir. Zira İmparatorluğun çöküş devrine şahitlik
etmiş bir edibin eserlerinde bu hislerin mevcudiyeti şaşırtıcı değildir. İftira-yı Taassubu yazdığı sene,
İmparatorluğun Afrika’daki son toprağı Trablusgarb İtalyanlarca işgal
edilmişti. Akabinde de Balkan savaşları meydana gelecekti. İftira-yı Taasuub, İmparatorluğun zevalinin Türk münevverleri
üzerindeki tesirlerini gösteren örneklerden yalnızca biridir. Ayrıca bu
makalede, doğulu bir aydının Batı’ya yönelttiği eleştiriler dikkate
alınacaktır. Zira bu risale bir oryantalizm eleştirisidir ve Batıda din ve
taassup ilişkisini örnekleriyle açıklamak niyetiyle yazılmıştır.
YÖRÜK “YÖRÜR MÜ?” YÖRÜK KELİMESİNİN ETİMOLOJİSİ ÜZERİNE BİR DENEME
Authors: YİĞİT Hayrettin
Published: January 2019

Orta Asya’dan yüzyıllar önce ayrılarak
dünyanın dört bir tarafına göç eden Türk boylarından birçoğu, zaman içerisinde
yerleşik hayata geçerken bazı boy ve aşiretler ise konar-göçer yaşamaya devam
etmiştir.  Bu konar-göçer hayat tarzını
benimseyen Oğuz boylarının birçoğu Anadolu’da Kızılırmak yayının batısından
İçel’i de içine alan çizginin batısında kalan bölgeler ile Rumeli topraklarına
kadar gelmişler ve yaşamlarını tamamen hayvancılığa bağlı olarak kışın ovalarda
yazın da yaylalarda sürdürmüşlerdir. Anadolu’da konar-göçer bu topluluklara
Yörük-Türkmen adı verilmiştir. Sosyo-kültürel yaşantılarına bağlı olarak
kullanılan yörük kelimesi tarihi
belgelerde 14. yüzyıldan itibaren kullanılmıştır. Kelime Anadolu ağızlarında yogrük, yörügen yörük, yürük, yuvruk, yüğrük,
yürük, yuvrük, yüyrük gibi fonetik değişikliklere uğramıştır. Söyleyiş
farklılıklarından dolayı yörük
kelimesinin köken olarak yorı-, yürük,
yüğrük kelimelerinden hangisinden geldiği tartışmalara neden olmuş ve net
bir sonuca varılmadığı görülmüştür. Makalede bu kelimelerin Türkçenin ilk
eserlerinden itibaren kullanımı ve sözlüklerdeki anlamları verilerek genel bir
kanıya varmak amaçlanmıştır.
PESQUISA EM ENSINO DE FÍSICA ANÁLISE DA PUBLICAÇÃO EM PERIÓDICO INTERNACIONAL ENTRE OS ANOS DE 2006 E 2017
Authors: Shigunov Neto Alexandre , Silva André Coelho da
Published: January 2019

Este artigo pretende apresentar uma análise das pesquisas sobre Ensino de Física publicadas na Revista Electrónica de Investigación en Educación en Ciencias entre os anos de 2006 e 2017. No levantamento de dados, foram identificados 28 artigos que tratam especificamente da temática Ensino de Física. Categorizamos os trabalhos em quatro assuntos: Formação Inicial de Professores, Formação Continuada de Professores, Trabalho Docente e Políticas Públicas e Currículo. Destacamos que as principais temáticas investigadas nos artigos foram Trabalho Docente e Políticas Públicas e Currículo, respectivamente.
The influence of etiological factors on immunoreactivity in patients with community-acquired pneumonia
Authors: Rvacheva A. V. , Pustovalov A. A. , Zykov K. A.
Published: January 2019

The aim of this study was to uncover the characteristics of immunoreactivity in patients with community-acquired pneumonia, depending on the pathogen. The inflammatory process caused by various pathogens, has its own characteristics and affects the course of the disease. The study of the mechanisms of these complex interactions can improve the understanding of the processes occurring in community-acquired pneumonia, and, therefore, develop individual approaches to the therapy depending on the etiological factor.
Afterword: A Response Essay
Authors: Kauanui J. Kēhaulani
Published: January 2019

This response addresses aspects of biopolitical regulations by Canada, El Salvador, Australia, and the United States, as critically analyzed in the special issue. Each piece offers much to illuminate different modalities of regulating Indigenous lifeways and Indigenous peoples' resistance to them on myriad grounds, and this response engages three particular themes that emerge from these articles: (1) structural genocide in settler-colonial states' attempts at deracination; (2) Indigenous peoples' agency with regard to anti-normalization; and (3) decolonial resistance outside of imposed settler-colonial binaries. All three aspects challenge the “logic of elimination of the Native” that, as theorized by Patrick Wolfe, is endemic to settler colonialism. The piece also offers some thoughts on these same three key nodes in the case of Hawai‘i and the United States.
The Study of the Relationship between Parsian Bank’s Knowledge Management and its Financial Performance
Authors: Jamshidi Ali , Grey Omid
Published: January 2019

Present research’s goal is to study the relationship between knowledge management of Parsian Bank and its financial performance. The statistical population consists of 220 executives, assistants and postgraduate staff in banking and financial management. The statistical sample consists of 144 of them who were determined according to the Morgan Table. This research uses quantitative and survey method and it has a practical purpose. The results show that there is a meaningful relationship between the research variables and that the relationship between them includes strength and weakness.
A case of idiopathic edema after opioid abuse cessation: can failed aldosterone escape be implicated?
Authors: Ratnam Ashutosh , Sashindran V. K. , Kanwar Anup
Published: January 2019

Edema is a recognized complication of ongoing heavy opioid use, regardless of the means of delivery or the specifics of the drug in question. The mechanism responsible remains incompletely understood. Hypotheses currently offered include increased Anti-Diuretic Hormone (ADH) secretion, histamine-mediated permeability changes, independent opioid-receptor mediated fluid retention and an exacerbation of pre-existing vascular compromise. Authors report a case of a 39yr old lady in whom edema emerged 7 months after cessation of opioid abuse. All secondary causes of edema were excluded by an exhaustive battery of investigations. The edema failed to recede with loop diuretics, and resolved only on institution of spironolactone, on which she maintained improvement. This case study reinforces hypotheses of ADH likely mediating opioid associated edema and suggests that aldosterone receptor antagonists are probably a superior class of drugs in opioid-associated edema. It also suggests that the physiological changes caused by opioid use that are responsible for edema are likely stable and persist well beyond the period of actual use. Reformed opioid abusers who never received OST are a huge population whose unique physiological status is likely to yield valuable insights into not just the pathology of opioid-abuse related edema, but the pathology of opioid use as a whole.
Effect of socio demographic profile on knowledge, attitude and practices of mothers regarding breastfeeding of Lucknow district
Authors: Ojha Sachi , Srivastava Shitanshu , Gupta Pratibha , Agrawal Divyanshu
Published: January 2019

Background: Breastfeeding is the ideal source of nutrition for first six month of life which is globally recognised. There are various advantages of optimal breastfeeding but still breastfeeding rates in Uttar Pradesh is only 56%. This might be attributed to various social, cultural and economical factors. Since there is limited local data on the knowledge, attitudes and practices of women toward breastfeeding. hence, we planned this study to assess knowledge, attitude and practices (KAP) of mothers regarding breastfeeding and influence of sociodemographic profile on them.Methods: A cross sectional study was conducted on 200 mothers coming to the rural and urban areas of a district with infants between 0-6 months. The data was collected using a predesigned questionnaire based on KAP about breastfeeding. The data was analyzed using (SPSS) version 21.0.Results: Our study shows that regarding knowledge of breastfeeding, in rural group 42% considered colustrum as first breast milk. In contrast in urban group, 63% were aware that it was first breast milk (p=0.003). Regarding practices, 56% of rural women had started breastfeeding within one hour while only 38% of urban women did the same (p=0.011). Regarding attitude, 77% women of urban area agreed regarding goodness of colostrum for health followed by 48% of rural women (p≤0.001). Most of the women agreed to the belief that a baby should burp after feeding (94% rural and 91% urban).Conclusions: The Gap between KAP regarding breastfeeding exists in rural and urban setups. So, proper stratgies should be planned depending on socio-demographic profile.
Depression and quality of life in family caregivers of individuals with psychiatric illness
Authors: . Aarti , . Ruchika , Kumar Rajesh , Varghese Arun
Published: January 2019

Background: Psychiatric illnesses are mushrooming more than any physical illness. Change in health care delivery system emphases the need of family caregivers. Providing care for a psychiatric patient is demanding and challenging task leads psychosocial distress and negative impacts in quality of life. The study aims to determine depression, quality of life and their association with sociodemographic variables of family caregivers.Methods: Sample consisted 150 family caregivers of individual with psychiatric illness seeking psychiatric outpatient department services. Physical health questionnaire (PHQ-9) and World Health Organization quality of life –BREF (WHOQoL-BREF) was used to ascertain information on depression and quality of life. A relevant descriptive and inferential statistics was applied to compute results.Results: Findings exhibit that environmental quality of life domain was severely affected in caregivers. Further, 24% caregivers reported symptoms of moderate-severe depression. Occupation of caregiver found significant association with physical (p=0.001), psychological (p=0.001), social (p=0.016) and environmental (p=0.001) domain of QoL. Support from society also expressed significant association with psychological (p=0.001), social (p=0.007) and environmental (p=0.044) domain of QoL. Further, education of the caregiver shows significant association with physical (p=0.000), psychological (p=0.000), social (p=0.002) and environmental (p=0.000) domain of QoL.Conclusions: Findings of the study sensitize policy makers and administrators to consider the need based psychiatric rehabilitation and implement it to reduce psychological distress and improve the quality of life of caregivers.
An Ophthalmic Changes in Patients with Chronic Obstructive Pulmonary Disease: Case-Control Study
Authors: Brandt Carlos Teixeira , De Souza Milena Amorim , Gadelha Diego Nery Benevides , Melo Maria Cecília Santos Cavalcanti , Cruz Rita de Cássia Santa
Published: January 2019

Purpose: To evaluate the prevalence of ophthalmological changes in patients with Chronic Obstructive Pulmonary Disease (COPD) cared for at the Pneumology and Ophthalmology Departments at Medical School Unifacisa-Campina Grande-Paraiba-Brazil.Materials and Methods: Twenty-two smoker patients with COPD (study group) and 22 healthy controls that underwent routine ophthalmological examination (control group) were enrolled in the investigation. They were homogeneous regarding age, gender, presence of Systemic Arterial Hypertension (SAH) and Diabetes Mellitus (DM). They were examined for the presence of cataract and Age Related Macular Disease (AMD).Results: The prevalence of ophthalmologic changes was significantly different in the two groups. Eight (36.4%)patients presented with cataract requiring surgical intervention, while one (4.5%) person in the control group had cataract (p = 0.0212). Regarding AMD, 10 (45.5%) smoker COPD patients had this disease, whereas in the control group, one (4.5%) person had this disease (p = 0.0039).Conclusion: From the results one can conclude that there is strong association between smokers diagnosed with COPD with cataract and AMD patients, reinforcing the need for a protocol for referral of these patients to the ophthalmologist.
MUNDO DO TRABALHO, GÊNERO E POLÍTICAS PÚBLICAS: o papel do feminismo estatal nessa relação
Authors: Martins Barby de Bittencourt
Published: January 2019

Este texto tem como objetivo tecer algumas considerações acerca do papel do feminismo estatal na relação entre as políticas públicas, o mundo do trabalho e a questão de gênero. Para tal, é realizada uma busca entre as autoras feministas sobre o que fora produzido até então acerca dessa temática. A presença da perspectiva de gênero nos espaços decisórios do Estado contribuem para a implementação de políticas capazes de promover mudanças nos padrões de desigualdade de gênero, em especial no mundo do trabalho? Conclui que a presença da mulher no Estado sinaliza uma mudança de paradigma, embora lenta e gradual. Todavia, o campo das políticas públicas relacionadas ao mundo do trabalho se apresenta mais resistente à perspectiva de gênero, como demonstram algumas autoras.Palavras-chave: Feminismo estatal. Políticas Públicas. Trabalho. Gênero.
Lentes de contacto blandas desechables diarias versus reutilizables: una revisión de las complicaciones en su porte
Authors: Goñi Boza Esteban
Published: January 2019

Introduction A bibliographic research was carried out to examine the main complications that occur in the wearing of soft contact lenses. Objective: To compare complications in ocular surface in contact lens wearers regarding daily disposable soft contact lenses versus reusable soft contact lenses. Methodology By means of a review of studies published since 2010 through the meta-search engine Google Scholar, twenty articles were detected that met selection parameters. Studies published in three languages (English, Portuguese and Spanish) were analyzed, and exclusive searches were conducted in each language. Results The content of the studies was classified into three main parameters, which serve as comparative elements between daily disposable soft contact lenses and reusable soft contact lenses: a) handling, maintenance and storage b) useful life of lenses and c) biocompatibility. Conclusions According to these studies, the main problems associated with the use of soft contact lenses may be due to poor handling and hygiene of both lenses and their accessories, and to the use of cleaning solutions. Regarding these aspects, daily disposable soft contact lenses present some advantages, besides the factor of useful life. As for biocompatibility, both types of contact lenses showed the same characteristics and potential complications.
Gene therapy in the treatment of retinal dystrophies
Authors: Hernández Luz Ángela , Tachack Abril Ginna Tatiana , Henao Calderón José Luis
Published: January 2019

Gene therapy is defined as procedures to transfer genetic material to specific organs, with the purpose of producing therapeutic effects that seek to correct defects or genetic diseases, either directly (in vivo) or indirectly (ex vivo), by using cells as a delivery vehicle. Eye diseases, mainly macular diseases, have a high genetic component. This has led to several studies suggesting alternative treatments such as gene therapy for their treatment. Studies have concluded that gene therapy is a novel and promising therapeutic strategy that could provide a more effective way to treat these diseases. The objective of this article is to present a review of the concepts of gene therapy, types of vectors, and gene therapy in retinal dystrophies.
AnÃ¡lise de Conteúdo das Justificativas das Propostas de Emenda à Constituição que Tratam da Maioridade Penal
Authors: Holanda Ariela Oliveira , Oliveira-Castro Jorge , Silva Thays da Cruz
Published: January 2019

A questão da maioridade penal é tema de 43 Propostas de Emenda à Constituição que intentam mudar a legislação atual. Com o objetivo de identificar os argumentos mais frequentes nessas Propostas, os textos de suas justificativas foram analisados por dois métodos diferentes. O Estudo 1 agrupou esses argumentos em categorias, que foram submetidas à análise de concordância entre juízes. No Estudo 2, o texto das justificativas foi submetido à análise lexicográfica por meio do programa IRAMUTEQ. Em ambos os estudos, os argumentos mais recorrentes foram: o critério etário é insuficiente para presumir capacidade de imputabilidade; o ordenamento jurídico atual e o Direito Comparado evidenciam que adolescentes devem ser penalmente responsabilizados; e mudanças na legislação são necessárias à redução da criminalidade. Erros lógicos e conceituais, aliados à carência de evidências empíricas, nos textos das Propostas, podem levar a conclusões imprecisas e, consequentemente, a tomadas de decisão que conduzam a resultados indesejáveis.
A estreia literária de Sérgio Milliet: Par le Sentier
Authors: Pinheiro Valter Cesar
Published: January 2019

Em 1917, em Genebra, Sérgio Milliet lançou uma coletânea de versos neorromântico-simbolistas escritos “à maneira de” Baudelaire, Verlaine e Samain: Par le sentier. Ausente do acervo das principais bibliotecas do país, a obra inaugural de um dos maiores nomes da crítica literária e artística brasileira do século XX permanece desconhecida do público leitor. Assim, converte-se no principal objetivo do presente texto apresentar alguns comentários acerca desse livro de estreia, aos quais se acrescentam apontamentos de caráter biográfico relativos à primeira passagem do autor pela Europa e notas alusivas ao Carmel, grupo literário responsável pela revista em que Milliet publicou seus primeiros poemas e pela editora que colocou Par le sentier em circulação.
O inferno é verde e “As palavras” de Leslie Kaplan em tradução (inédita) para o português
Authors: Féres José Roberto Andrade
Published: January 2019

Leslie Kaplan, nascida em Nova Iorque em 1943, mas criada desde muito cedo na França, escreve peças de teatro, romances, poemas, teoria, crítica literária e cinematográfica, tudo isso, sobretudo, em língua francesa. Poucas traduções da sua obra são encontradas no Brasil, e essa escassez de textos seus em português é, certamente, um dos motivos que me levaram a selecionar e traduzir dois de seus poemas longos (ainda inéditos na nossa língua, mas que serão publicados em breve pela editora Luna Parque): O inferno é verde [L’enfer est vert] e “As palavras (escrever, literatura e sociedade)” [Les mots (écrire, littérature et société)]. A poesia de Kaplan traz à mente questões sobre a tradução de poemas que muito se assemelham à prosa (embora seus versos livres nem sempre sejam tão livres assim) e reflexões sobre como se pode traduzir um texto escrito em mais de uma língua e que aproxime culturas aparentemente muito distantes umas das outras, pois O inferno é verde, cujo ponto de partida é uma viagem da escritora a Recife, faz uso das línguas francesa, inglesa e portuguesa. Trechos da tradução são analisados em comparação com os originais e escolhas tradutórias são justificadas com o auxílio de diversos escritos que concernem ao ofício, inclusive com as próprias palavras de Leslie, que afirma que “traduzir é sexy”.
Escrever de volta: Anne Carson, Emily Dickinson
Authors: Martins Helena Franco
Published: January 2019

Anne Carson é poeta, ensaísta, tradutora e professora de letras clássicas. Uma das forças reconhecidas de sua obra publicada é o transbordamento singular que promove entre atos de escrita que costumam se distribuir por esses diferentes ofícios. Com uma liberdade e uma exatidão improváveis, misturam-se ali poesia, tradução, ensaio, escólio, crítica literária, conferência, libreto, entrevista e assim por diante. É de fato uma obra que corporifica de maneira admirável a tão falada reciprocidade que une o escrever, o ler e o traduzir. Proponho aqui uma reflexão pontual sobre os modos como esse enlace se dá em Autobiography of Red: A Novel in Verse. Exploro a hipótese de que uma forma quase paradoxal de atenção aos fatos preside os gestos de leitura, tradução e escrita poética que Carson encena e imbrica nesse seu inclassificável livro. Dou ênfase especial ao estatuto do poema de Emily Dickinson que a autora traz ali como epígrafe. É com uma tradução desse poema que abro a minha reflexão aqui.
Os montes de Marguerite de Navarre. Comentários sobre a epístola dos Cauterets (1549)
Authors: Bôas Luciana Villas
Published: January 2019

Escrita por Marguerite de Navarre em 1549, a epístola dos Cauterets pertence à longa tradição de ascensões à montanha que culminam em formulações paradigmáticas de subjetividade. Este ensaio explora o nexo entre montanha, natureza e subjetividade, interpretando a epístola à luz de modelos anteriores articulados por Dante, Petrarca, bem como à luz dos salmos e das Escrituras. Ao mesmo tempo, revisita a tradição que liga a invenção da paisagem à descoberta do sujeito moderno e argumenta que a epístola dos Cauterets possibilita uma reconsideração crítica das premissas histórico-filosóficas do conceito de modernidade. (Inclui, ao final do artigo, original da "Epístola dos montes Cauterets" e tradução do poema por Luciana Villas Bôas e Sérgio Alcides).
The Impact of PQ4R Strategy Use on EFL Students' English Reading Comprehension
Authors: Lailatul Khusniyah Nurul -
Published: January 2019

The aim of this study is to examine the effect of PQ4R strategy on reading learning at English Study Program Universitas Islam Negeri Mataram. The research was used action research method. The sampling was taken by 34 students. The validity of data used credibility, transferability, dependability, and conformability. Reading comprehension ability achievement questions prepared by the researcher. It was used as the data collecting tool. These questions were implemented to both groups before the experiment. Independent sample t-test was used for data analysis. The result of the study that t-test result is t-stat (5.38) > t-table (1.99). It means that there is a significant difference was found in reading comprehension learning
La fijación de precios de reventa únicos por los editores de libros
Authors: Castañeda Sabido Alejandro Ildefonso , Martínez Quintero Oscar , Ruiz Pérez Daniel
Published: January 2019

Antecedentes: este trabajo analiza el impacto sobre el comportamiento de precios de libros debido a la aprobación de la Ley de Fomento para la Lectura y el Libro, publicada en el Diario Oficial de la Federación en julio de 2008.Metodología: se revisa la literatura académica relacionada con el tema y se analiza la evidencia estadística sobre el comportamiento de los precios antes y después de la aprobación de la ley.Resultados: la evidencia es compatible con la teoría del compromiso, que plantea que el productor aguas arriba (editores) mantiene su poder monopólico en el mercado aguas abajo (venta final) a través de una ley que obliga al mantenimiento de precios de reventa.Conclusiones: se concluye que la ley cambió la dinámica de fijación de precios aumentando la inflación en libros, por encima de lo que hubiera ocurrido en ausencia de su aprobación.
Deterioro cognitivo y dependencia alcohólica, implicaciones clínicas
Authors: Flórez Gerardo , Espandian Ashkan , Villa Rocío , Sáiz Pilar A.
Published: January 2019

Editorial del vol. 31-1
Double Discourse: Perspectives on Breast Screening Participation among Women and Their Health Care Providers
Authors: McBride Kate A , Fleming Catharine AK , George Emma S , Steiner Genevieve Z , MacMillan Freya
Published: January 2019

Obesity in Australia is rapidly rising, and is a major public health concern. Obesity increases risk of breast cancer and worse associated outcomes, yet breast screening participation rates in Australia are suboptimal and can be lower in higher risk, obese women. This study qualitatively explored barriers to breast screening participation in obese women in Australia. In-depth interviews (n=29), were conducted with obese women (BMI 30) and key health stakeholders. A disconnect between stakeholders’ and women’s perceptions was found. For women, low knowledge around a heightened need to screen existed, they reported limited desire to prioritize personal health needs, reluctance to screen due to poor body image and prior negative mammographic experiences due to issues with weight. Stakeholders perceived few issues in screening obese women beyond equipment limitations, and health and safety issues. Overall, weight was a taboo topic among our interviewees, indicating that a lack of discourse around this issue may be putting obese women at increased risk of breast cancer morbidity and mortality. Consideration of breast screening policy in obese women is warranted. Targeted health promotion on increased breast cancer risk in obese women is required as is a need to address body image issues and encourage screening participation.
Teleporting Digital Images
Authors: Mastriani Mario
Published: January 2019

During the last 25 years the scientific community has coexisted with the most fascinating protocol due to Quantum Physics: quantum teleportation (QTele), which would have been impossible if quantum entanglement, so questioned by Einstein, did not exist. In this work, a complete architecture for the teleportation of Computational Basis States (CBS) is presented. Such CBS will represent each of the possible 24 classical bits commonly used to encode every pixel of a 3-color-channel-image (red-green-blue, or cyan-yellow-magenta). For this purpose, a couple of interfaces: classical-to-quantum (Cl2Qu) and quantum-to-classical (Qu2Cl) are presented with two versions of the teleportation protocol: standard and simplified.
Unveiling Mesenchymal Stromal Cells’ Organizing Function in Regeneration
Authors: Nimiritsky Peter P. , Eremichev Roman Yu. , Alexandrushkina Natalia A. , Efimenko Anastasia Yu. , Tkachuk Vsevolod A. , Makarevich Pavel I.
Published: January 2019

Regeneration is a fundamental process much attributed to functions of adult stem cells. In last decades delivery of suspended adult stem cells is widely adopted in regenerative medicine as a leading mean of cell therapy. However, adult stem cells can not complete the task of human body regeneration effectively by themselves as far as they need a receptive microenvironment (the niche) to engraft and perform properly. Understanding of mechanisms underlying mammalian regeneration lead us to an assumption that improved outcomes of cell therapy requires a specific microenvironment generated in damaged area prior to stem cell delivery. To certain extent it may be achieved by delivery of mesenchymal stromal cells (MSC), not in dispersed form, but rather self-organized in cell sheets (CS) – tissue-like structures comprising of viable cells and microenvironment components: extracellular matrix and soluble factors deposited in the matrix. In this communication we highlight a potential role of mesenchymal stromal cells (MSC) as regeneration organizers and speculate that this function emerges in CS. This concept shifts our understanding of therapeutic mechanism underlying a widely known CS-based delivery method for regenerative medicine.
Pilot Attempt to Benchmark Spatial Resolution of an Electronic Imaging System Prototype for In-Process Electron Beam Melting Monitoring
Authors: Wong Hay , Neary Derek , Jones Eric , Fox Peter , Sutcliffe Chris
Published: January 2019

Electron Beam Melting (EBM) is an increasingly used Additive Manufacturing (AM) technique employed by many industrial sectors, including the medical device and aerospace industries. In-process EBM monitoring for quality assurance purposes has been a popular research area. Electronic imaging has recently been investigated as one of the in-process EBM data collection methods, alongside thermal/ optical imaging techniques. Despite certain capabilities of an electronic imaging system have been investigated, experiments are yet to be carried out to benchmark one of the most important features of any imaging systems – spatial resolution. This article addresses this knowledge gap by: (1) proposing an indicator for the estimation of spatial resolution which includes the Backscattered Electrons (BSE) information depth, (2) estimating the achievable spatial resolution when electronic imaging is carried out inside an Arcam A1 EBM machine, and (3) presenting an experimental method to conduct edge resolution evaluation with the EBM machine. Analyses of experimental results indicated that the spatial resolution was of the order of 0.3mm-0.4mm when electronic imaging was carried out at room temperature. It is believed that by disseminating an analysis and experimental method to estimate and quantify spatial resolution, this study has contributed to the on-going quality assessment research in the field of in-process monitoring of the EBM process.
Emerging and Reemerging Aedes-Transmitted Arbovirus Infections in the Region of the Americas: Implications for Health Policy
Authors: Espinal Marcos A. , Andrus Jon K. , Jauregui Barbara , Waterman Stephen Hull , Morens David Michael , Santos Jose Ignacio , Horstick Olaf , Francis Lorraine Ayana , Olson Daniel
Published: January 2019

The increasing geographical spread and disease incidence of arboviral infections are among the greatest public health concerns in the Americas. The region has observed an increasing trend in dengue incidence in the last decades, evolving from low to hyperendemicity. Yellow fever incidence has also intensified in this period, expanding from sylvatic-restricted activity to urban outbreaks. Chikungunya started spreading pandemically in 2005 at an unprecedented pace, reaching the Americas in 2013. The following year, Zika also emerged in the region with an explosive outbreak, carrying devastating congenital abnormalities and neurologic disorders and becoming one of the greatest global health crises in years.

The inadequate arbovirus surveillance in the region and the lack of serologic tests to differentiate among viruses poses substantial challenges. The evidence for vector control interventions remains weak. Clinical management remains the mainstay of arboviral disease control. Currently, only yellow fever and dengue vaccines are licensed in the Americas, with several candidate vaccines in clinical trials.

The Global Arbovirus Group of Experts provides in this article an overview of progress, challenges, and recommendations on arboviral prevention and control for countries of the Americas.
Police-Related Deaths and Neighborhood Economic and Racial/Ethnic Polarization, United States, 2015–2016
Authors: Feldman Justin M. , Gruskin Sofia , Coull Brent A. , Krieger Nancy
Published: January 2019

Objectives. To estimate the association between rates of police-related deaths and neighborhood residential segregation (by income, race/ethnicity, or both combined) in the United States.

Methods. We identified police-related deaths that occurred in the United States (2015–2016) using a data set from the Guardian newspaper. We used census data to estimate expected police-related death counts for all US census tracts and to calculate the Index of Concentration at the Extremes as a segregation measure. We used multilevel negative binomial models for the analyses.

Results. Overall, police-related death rates were highest in neighborhoods with the greatest concentrations of low-income residents (vs high-income residents) and residents of color (vs non-Hispanic White residents). For non-Hispanic Blacks, however, the risk was greater in the quintile of neighborhoods with the highest concentration of non-Hispanic White residents than in certain neighborhoods with relatively higher concentrations of residents of color (the third and fourth quintiles).

Conclusions. Neighborhood context matters—beyond individual race/ethnicity—for understanding, preventing, and responding to the occurrence of police-related deaths.

Public Health Implications. Efforts to monitor, prevent, and respond to police-related deaths should consider neighborhood context, including levels of segregation by income and race/ethnicity.
Using Animations of Risk Functions to Visualize Trends in US All-Cause and Cause-Specific Mortality, 1968–2016
Authors: Rudolph Jacqueline E. , Cole Stephen R. , Edwards Jessie K. , Whitsel Eric A. , Serre Marc L. , Richardson David B.
Published: January 2019

Objectives. To use dynamic visualizations of mortality risk functions over both calendar year and age as a way to estimate and visualize patterns in US life spans.

Methods. We built 49 synthetic cohorts, 1 per year 1968 to 2016, using National Center for Health Statistics (NCHS) mortality and population data. Within each cohort, we estimated age-specific probabilities of dying from any cause (all-cause analysis) or from a particular cause (cause-specific analysis). We then used Kaplan–Meier (all-cause) or Aalen–Johansen (cause-specific) estimators to obtain risk functions. We illustrated risk functions using time-lapse animations.

Results. Median age at death increased from 75 years in 1970 to 83 years in 2015. Risk by age 100 years of cardiovascular mortality decreased (from a risk of 55% in 1970 to 32% in 2015), whereas risk attributable to other (i.e., nonrespiratory and noncardiovascular) causes increased in compensation.

Conclusions. Our findings were consistent with the trends published in the NCHS 2015 mortality report, and our dynamic animations added an efficient, interpretable tool for visualizing US mortality trends over age and calendar time.
Agentes etiológicos de meningitis infecciosa en un hospital referencial de Chiclayo, Perú
Authors: Ventura-Flores Roberto , Failoc-Rojas Virgilio E
Published: January 2019

[No disponible]
POTENTIAL OF Alternanthera bettzickiana (REGEL) G. NICHOLSON FOR REMEDIATION OF CADMIUM-CONTAMINATED SOIL USING CITRIC ACID
Authors: Kanwal Urooj
Published: January 2019

The Alternanthera bettzickiana (Regel) G. Nicholson belongs to Amaranthaceae family and has great potential to decontaminate cadmium-affected soils. Organic acids including citric acids play a vital role in cadmium uptake and its detoxification. Thus, an experiment was performed to investigate the role of Alternanthera bettzickiana in phytoremediation of soils contaminated with Cd in the presence or absence of citric acids. Soils treated with different level of Cd (0, 25, 50, 100 mg kg-1 ) concentrations and citric acid (0, 250 and 500 µM) were used to grow plants. The results indicated that more Cd was accumulated in aerial parts of the plant as compared to underground parts. Biomass, photosynthetic pigment, and plant growth enhanced with the increasing level of Cd concentration in soil but it decreased at the highest Cd concentration in the growth medium. With the maximum applied dose of CA (500 µM), the plant height was significantly increased by 141, 107 and 90% at Cd level 25, 50 and 100 mg kg-1 , respectively. The activities of superoxide dismutase (SOD) and peroxidase (POD) enhanced with lower metal level (Cd 25, 50 mg kg-1 ), while reduced at the maximum Cd concentration (100 mg kg-1 ). With the maximum applied dose of (Cd 50+CA500), superoxide dismutase (SOD) in leaves and POD in leaves was significantly increased by 63 and 75%, respectively. It is concluded that Alternanthera bettzickiana has maximum ability to remediate moderately contaminated soils. Moreover, phytoremediation potential was further enhanced by the citric acid application. Enhancement of phytoremediation potential in Alternanthera bettzickiana was associated with citric acid-induced modulation in oxidative stress and antioxidant potential
Talent & Technology: Critical Skills for a Successful Career
Authors: JPT staff _
Published: January 2019

Talent & Technology

The recently published LinkedIn “Roadmap,” which utilized data from more than 500 million members combined with a survey of 2,000 business leaders, identified that soft skills are often more needed than hard skills. SPE recognizes that its members need to possess such skills—and more. Recently, the SPE Soft Skills Committee was renamed Business and Management Leadership (BML) to better represent the needs and missions of such skills in successful careers. The BML committee organized a panel session during the 2018 SPE Annual Technical Conference and Exhibition titled “Critical Skills for Career Success” where industry leaders provided their insights on what skills make a difference in one’s career, and how to develop and master critical skills to attain business and management leadership. The moderator of the panel was Maria Capello, Kuwait Oil Company. Panelists were Kamel Ben Naceur, ADNOC; Behrooz Fattahi, The EnerTrain Institute; Ford Brett, PetroSkills; Thomas Blasingame, Texas A&M University; and Janeen Judah, 2017 SPE President.

The key takeaway of the panel was that, no matter your position, entry-level or senior management, you must be able to manage and motivate people. Employers want and need people who can stretch out of their comfort zone and see change as an opportunity for growth and innovation. Having the ability to accept and adapt is important, because adjusting to a new environment is now part of the mod-ern world of working.

Ben Naceur, ADNOC’s chief economist, started the discussion. He has worked in 14 countries and experienced four price cycles in the oil industry, during which he envisioned and empowered his career progression into new roles. His vision grew with every new role, allowing him to understand the importance of soft skills. Ben Naceur started his career in a technical position within an R&D organization, shifting into the applications side of the industry, supervising complex hydraulic fracture stimulations, requiring immediate decision-making and the management of people from very diverse cultural settings. Later, he became Minister for Industry, Energy, and Mines in his home country, Tunisia, a huge responsibility he accepted mainly to be able to give back to his nation. During the panel discussion, he asserted that being able to continuously adapt to new jobs, new cultures, and new languages is of critical importance—and although diverse technical skills were essential for his career, Ben Naceur credits soft skills as the “building bridges” that enabled major course changes.

“People tend to judge you for what they can see but they don’t know what is inside you, and that is precisely the part you need to pay attention to,” said panelist Fattahi, 2010 SPE President. Further, “in the logical plane of your brain, 1 plus 1 is always 2. That’s logic…but not on the emotional plane. We always tend to train for logic but we do not pay attention to the emotional system.”