bluuebunny/crossref_metadata_2025 huggingface dataset:
PRE-OPERATIVE LUMBAR DRAINAGE VERSUS NO LUMBAR DRAINAGE IN PATIENTS UNDERGOING CLIPPING FOR RUPTURED ANEURYSMAL INTRACRANIAL BLEED
Authors: Singh Makkar Gourav , Singh Ishwar , Sachdeva Binny
Published: April 2023

Aim:. To compare effectiveness of Pre-operative lumbar drainage and Non- Lumbar Drainage in surgical dissection of
ruptured intra-cranial aneurysm. A prospective, ran Materials and methods:. domized, comparative study was conducted on
50 patients of aneurysmal SAH in the departmemt of neurosurgery starting from January 2020. Patients with deranged coagulation prole,
meningitis contradicting placement of intra-thecal drain, infection at lumbar region and patients not giving consent were excluded. Patients were
randomly assigned to two group A and group B. Patients of group A were subjected to clipping of aneurysm with Pre-operative lumbar drain
placement after induction of anaesthesia and patients ofgroup B were subjected to clipping of aneurysm without lumbar drainage.
Results
Ÿ Post-operative vasospasm- The post-operative vasospasm was present in 24.0% of the cases of lumbar drain group and 52.0% of the cases
without lumbar drain group which was statistically signicant.
Ÿ Post-operative early infarct -Post-operative early infarct was present in 8.0% of the cases in lumbar drain group and 32.0% of the cases
without lumbar drain group which was statistically signicant.
Ÿ Post-operative late infarct- The post-operative late infarct was present in 4.0% of the lumbar rain group and 24.0% of the patients without
lumbar drain group which was statistically signicant
Ÿ Post-operative ICU stay- Post-operative ICU stay was less than or equal to 7 days in 84.0% of the cases in lumbar drain group and 56.0% of
the without lumbar drain group which was statistically signicant
Ÿ On discharge motor decit- On discharge motor decit was present in 20.0% of the cases in lumbar drain group and 24.0% of the cases in
without lumbar drain group which was not statistically signicant
Conclusions: This study was undertaken mainly to study the efcacy of lumbar drainage in management of ruptured aneurysm with SAH. This
study had shown that, the lumbar drain was useful in preventing the vasospasm, early and late infarct. The number of days of stay in ICU was also
lower in lumbar drain group than the control group. In addition lumbar drain does provide help to surgeon in surgical dissection of sylvian ssure
as well as dissection around aneurysm
THE USE OF CDX BRUSH BIOPSY IN ORAL CANCER DETECTION
Authors: Akhavan Sanam , Agarwal Vatika
Published: April 2023

Oral squamous cell carcinoma is the most common group of cancers that affect the head and neck region. Detection in its
early stages is a key factor to improve the survival rate and oral health professionals must play a leading role in this
endeavor. Various diagnostic aids have been developed as an adjunct to the routine oral cancer screening, one of which is the oral brush biopsy
(known as the OralCDx® Brush Test). The technique is non-invasive and relatively simple, allowing a painless and easy way to evaluate a
suspicious lesion. The purpose of this article is to review the OralCDx test including its indications, advantages, disadvantages and applications in
dentistry
MINIMALLY INVASIVE VERTICAL EXTRACTION SYSTEM BENEX – A NARRATIVE REVIEW
Authors: Chenchev Lyubomir , Ivanova Vasilena
Published: April 2023

The aim of this review is to assess data in published clinical papers about the minimally invasive properties and
application of the vertical tooth extraction system Benex (Benex extractor, Hager & Meisinger GmbH, Neuss, Germany
and Helmut Zepf Medizintechnik, GmbH, Tuttlingen, Germany). A search of PubMed, ResearchGate and Google Scholar was conducted without
a set publication year limit, using different keywords. The search found 15 papers, which were all included in the review. Benex system is an
effective minimally invasisve tooth extraction device, especially for teeth with single roots. Authors have found a variety of other effecive
applications of the system, which further conrms its minimally invasive properties
Blockchain and COVID-19 Pandemic: Applications and Challenges
Authors: Ahmad Raja Wasim , Salah Khaled , Jayaraman Raja , Yaqoob Ibrar , Ellahham Samer , Omar Mohammed
Published: April 2023

The year 2020 has witnessed the emergence of coronavirus (COVID-19) that has rapidly spread and adversely affected the global economy, health, and human lives. The COVID-19 pandemic has exposed the limitations of existing healthcare systems regarding their inadequacy to timely and efficiently handle public health emergencies. A large portion of today's healthcare systems are centralized and fall short in providing necessary information security and privacy, data immutability, transparency, and traceability features to detect fraud related to COVID-19 vaccination certification, and anti-body testing. Blockchain technology can assist in combating the COVID-19 pandemic by ensuring safe and reliable medical supplies, accurate identification of virus hot spots, and establishing data provenance to verify the genuineness of personal protective equipment. This paper discusses the potential blockchain applications for the COVID-19 pandemic. It presents the high-level design of three blockchain-based systems to enable governments and medical professionals to efficiently handle health emergencies caused by COVID-19. It discusses the important ongoing blockchain-based research projects, use cases, and case studies to demonstrate the adoption of blockchain technology for COVID-19. Finally, it identifies and discusses future research challenges, along with their key causes and guidelines.
Situational Awareness for Industry 5.0 and Mobile Robotics: A Review
Authors: Höyhtyä Marko
Published: April 2023

Intelligent networking of machines, processes and robots in the Industry 5.0 era enables automated decision-making and efficient operations. Situational awareness (SitAw) lies at the core of the development, providing understanding of what is happening around us. It uses inputs from sensors and humans and provides the ability for robots to survive in an uncertain environment. This paper defines the situational awareness system and the general SitAw architecture and shows how it can be applied to numerous use cases. We discuss time-scales of operation and show how real-time and non-real-time information are simultaneously used to provide real-time services. Predictive capabilities and ability to react to anomalies are essential part of proactive and safe operations. In contrast to typical focus on short range wireless connectivity, we highlight the importance of satellite technologies as an enabler in many application areas including smart farming, mobile robot swarms and autonomous shipping. Future research directions including three-dimensional SitAw and industrial metaverse are given.
Sound models for synthesis: a structural viewpoint
Authors: De Poli Giovanni
Published: April 2023

For the needs of music production and multimedia art, sound synthesis algorithms are needed which are versatile, responsive to user’s expectations, and having high audio quality. It is useful to organize our intuitive sound abstracts into models. A computational model can be used for representing and generating a whole class of sounds, depending on the internal structure of the model and on the choice of control parameters. We will review some of the most important computational models that are being used for sound synthesis in musical production from the viewpoint of the model structure. Moreover, the Centro di Sonologia Computazionale of Padova University has done research on synthesis models for a long time and the main achievements in both the scientific and musical fields will be presented.
La Sintesi del suono in Iannis Xenakis. Indagine di una ricerca compositiva
Authors: Di Scipio Agostino
Published: April 2023

Unlike many composers of his generation, Iannis Xenakis personally devised and implemented the sound synthesis techniques used in some of his creative efforts. Eight of his works feature – in part or exclusively – sounds obtained with analogue or digital synthesis techniques, in a time span that goes from Analogique B (1959) to S.709 (1994). All of his electroacoustic music after La Légend d’Eer (1977) has sounds synthesized with computer technology. The sound synthesis procedures he devised, reflect peculiar operational and technological conditions, and indeed represent tokens of musical and sonological knowledge characteristic of a truly unique practice. In this paper we provide a survey of Xenakis’s efforts with sound synthesis, delineating their historical path through the experimenting of different technical contexts of material production and the corresponding theoretical and musical implications. Xenakis’ approach on sound synthesis is viewed as a domain of design of direct compositional relevance. Across subsequent steps in his carrier, Xenakis’s notion of ‘synthesis’ appears as a process or device generative of sound and music at once, in a single compact constructive gesture or strategy making it difficult to tell matter from form. Gradually, the musical work’s identity seemed to incorporate not just a specific linguistic-formal configuration, but the set of conditions of possibility elaborated by the composer – that is, eventually, the computer programming code (Gendy3, 1992). Iannis Xenakis’ commitment to crafting sound generation techniques – before using them to also craft music – witnesses at an attitude in which the appropriation of the material means of creative labour is an irreducible precondition for freedom of expression and musical aesthetics.
РЕЗЕРВНА ФОТОЕЛЕКТРИЧНА СТАНЦІЯ В УМОВАХ ПЕРІОДИЧНИХ ВІДКЛЮЧЕНЬ СПОЖИВАЧІВ ВІД ЕЛЕКТРОМЕРЕЖІ
Authors: Гаєвський О. Ю. , Гаєвська Г. М. , Іванчук В. Ю.
Published: April 2023

Робота присвячена розробці моделі та методики розрахунку резервної фотоелектричної системи (РФЕС), призначеної для підтримки локального споживача при періодичних відключеннях від електромережі. Запропоновані метод та алгоритм розрахунку, що засновані на рівняннях балансу енергії в системі протягом доби для заданих добових профілів навантаження та сценарію відключення. Метод дозволяє розрахувати необхідні розмірні параметри РФЕС: необхідну потужність масиву фотомодулів Pinst і сумар-ну ємність акумуляторів Qinst. Змодельовані різні сценарії відключення для РФЕС, розташованої в Київській області, яка забезпечує підтримку добового навантаження 10 кВт. Отримані залежності параметрів Pinst і Qinst від характеристик сценаріїв відключень. Оцінена надійність резервного електропостачання при відхиленні енергії заряду батареї на початок доби від необхідного рівня. Представ-лений метод визначення розмірів РФЕС може бути використаний при проєктуванні систем локального резервного електропостачання житлових будинків або малих підприємств для умов воєнного стану.
АНАЛІЗ СТІЙКОСТІ НЕЛІНІЙНИХ ТЕПЛОВИХ ПРОЦЕСІВ У СЕРЕДОВИЩАХ ПРИ РІЗНІЙ ПРОСТОРОВІЙ СТРУКТУРІ ЗБУРЕНЬ
Authors: Бондаренко Д. В. , Матях С. В. , Рєзцов В. Ф. , Суржик Т. В. , Шейко І. О.
Published: April 2023

Особливістю процесів взаємодії сонячного випромінювання з матеріалами, які використовуються в геліоенер-гетиці та фотоенергетиці, є нелінійна залежність густини тепловиділення від температури. При наявності просторових збурень внаслідок розвитку нестійкості, яка в цій роботі аналізується на основі синергетичної методології, це може призвести до зростання амплітуди збурень, зокрема коливань величини збурень у часі. Внаслідок цього зменшується енергоефективність процесу перетворювання сонячної енергії, ресурс та надійність відповідного обладнання. Тому аналіз стійкості має не тільки теоретичне, але й практичне значення під час проєктування систем сонячної енергетики, вибору відповідних функціональних матеріалів та технологій функціонування. Бібл. 3.
ОСОБЛИВОСТІ ЗАСТОСУВАННЯ ЧИСЛОВОГО МЕТОДУ РІШЕННЯ МАТЕМАТИЧНОЇ МОДЕЛІ НЕСТАЦІОНАРНИХ ЕЛЕКТРОМЕХАНІЧНИХ ПРОЦЕСІВ У СИСТЕМІ ВІТРОЕЛЕКТРИЧНА УСТАНОВКА – ЕЛЕКТРОГІДРАВЛІЧНИЙ НАСОС СТАНЦІЇ ОПРІСНЕННЯ МОРСЬКОЇ ВОДИ
Authors: Васько П. Ф. , Мазуренко І. Л.
Published: April 2023

Висвітлено актуальність задачі опріснення морської води в промислових обсягах у межах європейської програми «2x40 GW Green Hydrogen Initiative», відповідно до якої в Україні передбачається спорудження 10 ГВт потужностей електролізерів для виробництва зеленого водню з використанням енергії офшор-них вітроелектричних станцій в Азово-Чорноморському регіоні. Розглянуто структурну схему елек-троживлення електрогідравлічних насосів станції опріснення морської води для електролізера від вітроелектричних установок. Об'єкт дослідження представлено двомасовою динамічною системою обер-тового руху, яка функціонує під впливом стохастичної зміни швидкості вітру. Одна з інерційних складових містить в собі вітротурбіну з генератором, а друга – гідравлічний насос з приводом від електродвигуна. Взаємовплив складових здійснюється через лінію електропередачі. Експлуатаційні комутаційні операції та функціонування регуляторів супроводжуються виникненням перехідних короткотривалих та довготривалих процесів. Перебіг нестаціонарних процесів описується системою диференціальних рівнянь, яка класифікується як жорстка через суттєву відміннсть значень сталих часу елементів технологічної схеми електроживлення двигунів гідронасосів. Особливості застосування числового методу інтегрування математичної моделі розглянуто на основі тестової задачі з коефіцієнтом жорст-кості системи рівним 1000. Досліджувалось застосування явних та неявних числових методів з аналізом похибки інтегрування в примежовому шарі короткотривалих регулювальних і комутаційних збурень та на інтервалі тривалості пориву швидкості вітру. Застосовувалась програмна реалізація методів в пакетах прикладних програм Matlab та Mathcad з використанням функцій автоматичної побудови матриці Якобі. Дискутується питання тестування числових методів на часовому інтервалі 600 с для отримання статистично стійких значень енергетичних показників системи електроживлення на основі вітроелектричних установок.
COMPARATIVE EVALUATION OF THE TEMPOROMANDIBULAR JOINT STRUCTURES AFFECTED BY TMJ DYSFUNCTION
Authors: Nespryadko Valeriy P. , Vovk Victoria V. , Bohatyrova Daryna I.
Published: April 2023

The aim: To investigate the individual anatomical features of the temporomandibular joint structures affected by TMJ disorders and compare them with those of asymptomatic patients.
Materials and methods: The sample consisted of 41 patients. The study group included 29 patients. The retroposition of the right mandibular head was observed in 16 patients, the anterior position of the right mandibular head – in 13 patients, the retroposition of the left mandibular head – in 19 patients, and the anterior position of the left mandibular head – in 10 patients. The control group consisted of 12 patients with an anterior or central position of the right and left mandibular heads.
Results: In the study group, a comparative analysis of the ABC angle on the right and left sides found no statistically significant difference in Student’s criterion (p=0.176). In the control group, a comparative analysis of the ABC angle on the right and left sides found no statistically significant difference in Student’s criterion (p=0.131). To identify a possible difference in the inclination of the articular tubercle in the study and control groups (anterior position of the mandibular head), calculations were carried out and when comparing two related samples using Wilkinson’s T-criteria, the difference is not statistically significant p=0.119. The mean values obtained using Student’s criterion did not reveal any statistically significant difference between both groups, р*=0,811.
Conclusions: A comparative analysis of the ABC angle in patients with TMJ dysfunction and the control group did not reveal any statistically significant dif¬ference. At the same time, there was no statistically significant difference between patients with the anterior and posterior position of the mandibular head.
SURGICAL TREATMENT OPTIMISATION OF RECURRENT ABDOMINAL WALL HERNIAS ASSOCIATED WITH LIGATURE FISTULA
Authors: Feleshtynsky Yaroslav P. , Derkach Krystina D.
Published: April 2023

The aim: To improve the efficiency of treatment of recurrent abdominal wall hernia associated with ligature fistula.
Materials and methods: We analysed the results of treatment of recurrent hernias with ligature fistula in 86 patients. 44 patients of group 1 were treated according to the developed algorithm (fistula and mesh explantation, wound debridement, mesh fixation and wound closure with antiseptic-containing polyurethane composite), 42 patient (group 2) were treated according to the traditional one.
Results: Decreased rate of seroma formation in group 1 if compared to group 2 was observed up to 6,7% against 23,8% (OR=0,23; 95%CI=0,06-0,92; р=0,038). Wound infection occurred in 1 (2,3%) case of group 1 against 7 (16,7%) of group 2 (OR= 0,12; 95% CI =0,01-0,99; р=0,027). 4 (9,5%) patients from group 2 developed recurrent ligature fistula (OR= 0,10; 95%CI= 0,01-1,90). Recurrence of hernia was observed in 1 (2,9%) patient of group 1 against 6 (17,7%) patients of group 2 (OR=0,14; 0,01-1,21; р=0,048).
Conclusions: Surgical treatment optimisation of recurrent abdominal wall hernia associated with ligature fistula improved the efficiency of treatment, which was proven by the obtained outcomes and relative risk of complications.
EFFECT OF INTERMITTENT FASTING ON CARBOHYDRATE, LIPID AND ULTRASONOGRAPHIC PARAMETERS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND PREDIABETES
Authors: Chubirko Ksenia I. , Hechko Mykhaylo M. , Griadil Taras I. , Chopey Ivan V.
Published: April 2023

The aim: To study intermittent fasting (IF) treatment in patients with non-alcoholic fatty liver disease (NAFLD) and prediabetes.
Materials and methods: Patients with NAFLD (n=95) were examined. The patients were divided into 2 groups: Group 1 – NAFLD with obesity, Group 2 – NAFLD and prediabetes. All patients in both groups had Body mass index (BMI) within the 2nd degree of obesity range (30.0 kg/m2 to 34.5 kg/m2).
Results: The effect of IF on anthropometric parameters, carbohydrate and lipid levels in patients with NAFLD with obesity and NAFLD with prediabetes, 6 and 12 months after treatment is shown.
Conclusions: Intermittent fasting has a statistically significant effect on anthropometric parameters in NAFLD with obesity and NAFLD with prediabetes. Metformin administration after intermittent fasting in 12 months showed a statistically significant improvement in lipid and carbohydrate profiles.
DETERMINANTS OF VACCINE HESITANCY AMONG PARENTS IN KYIV
Authors: Grechukha Yevgenii O. , Gnyloskurenko Ganna V. , Lapii Fedir I. , Volokha Alla P.
Published: April 2023

The aim: Assess of the determinants of vaccine hesitancy among parents regarding their children in Kyiv, Ukraine.
Materials and methods: Direct interview with survey on parents’ attitudes and behaviors regarding their children’s immunization. Vaccination hesitancy was determined with the median of responses and by self-reported question. The study was conducted among parents, whose children were patients at Children’s hospitals, attend schools and kindergarten in Kyiv, Ukraine.
Results: The median of vaccine hesitancy was 14,2% of 797 parents in Kyiv. The results show that 81.5% of parents with university degree agree that vaccination of their child is important for the health of others in the community, whereas only 67% (p≤0.05) of people who graduated from high school supported this view. The only reason to vaccinate their child is so they can enter daycare or school was marked by only 4.5% of parents with university education background and 15.3% of people who graduated from high school (p≤0,05).
Conclusions: Vast majority of interviewed parents think that vaccines are important for their children; meanwhile only half of the parents fully trust the current National Immunization Schedule and fully agree that question of child vaccination is their responsibility. Consulting pediatricians and GPs are associated with more parental confidence than other medical workers. Main source of negative information about vaccines is the Internet, but some part of parents who received negative information indicates health care workers as a source of this information. Majority of parents thinks that their religion is compatible with vaccines.
INFLAMMATORY RESPONSE AND METABOLIC ADAPTATION IN CHILDREN WITH ACUTE RESPIRATORY PATHOLOGY
Authors: Horlenko Olesya M. , Pikina Iryna Yu. , Prylypko Lyubomyra B. , Derbak Mariya A. , Debretseni Olena V. , Debretseni Kristian O. , Myhovych Ivan I.
Published: April 2023

The aim: To investigate the parameters change of the general immune responds and endocrine metabolism in the children with Acute Respiratory Pathology and their correlational relationship.
Materials and methods: The study group included: school-age children (10-14 years old) with a diagnosis of acute respiratory disease (ARI) as a general group of respiratory tract inflammatory diseases, of viral and bacterial origin (n=40), which included local inflammatory lesions of the respiratory tract and presented with acute pharyngitis (60.0%), acute bronchitis (20%), acute tonsillitis (22%) and a control group (n=25), identical in age and sex. The research was conducted at the clinical base of the CNE «UCChH» of the Uzhhorod City Council. General clinical, immunological studies, inflammatory response of the child’s body were conducted. Statistical analysis of the results of the examination of patients was carried out using the Statistics for Windows v.10.0 computer program (StatSoft Inc, USA). The evaluation of the obtained results was carried out using parametric and non-parametric methods
Results: The inflammatory response parameters of the child’s organism present indicative increases in the levels of cytokines with a significant predominance in comparison with the data of the children control group: the level of IL-1 increased in 2 times, IL-4 – in10 times, IL-6 – in 1.5 times, γ-IFN – in 3 times, TNF-α – in 25 times, Neopterin – in 9 times. The data of the general immune response indicate a 2-times increasing in the level of IgM (3.85 ± 1.89 g/l, p<0.01) and IgG level increased in 10 times (147, 35 ± 56.12 g/l, p< 0.01). The, according to the obtained data but, in comparison with the data of the control group. There are significant differences in the levels of Leptin (р< 0.01), C-peptide (р< 0.01), Thyroid stimulating hormone ( p<0.01), Free thyroxine (p=0.002). The Leptin level, which is at the upper limit of the reference, the level of Thyroid stimulating hormone at the lower limit of the reference, and the slight predomi¬nance of the C-peptide level are noteworthy. Predominance of reliable correlations of pro-inflammatory cytokines IL 1, 4, 6 of varying degrees (r=0.34-0.45) are observed. Only IgG with Free triiodothyronine (r=0.45,p=0.004), IgE with Thyroid peroxidase antibody (r=-0.45,p=0.004) were identified as statistically significant correlations with high reliability.
Conclusions: The obtained date presents the increasing of the levels Cytocines (Il -1,4,6) in 2-10 times. The IgG level increased in 10 times and IgM – in 2 times. The indicators of endocrine metabolism are within the reference values. Reliable correlations of pro-inflammatory cytokines IL 1, 4, 6 of varying degrees (r=0.34-0.45) are observed. IgG with Free triiodothyronine (r=0.45,p=0.004) have significant reasonableness.
PHYSICAL HEALTH OF FEMALES FROM THE LOWLAND DISTRICTS OF ZAKARPATTIA ACCORDING TO THE METABOLIC LEVEL OF AEROBIC AND ANAEROBIC ENERGY SUPPLY DEPENDING ON THE COMPONENT BODY COMPOSITION
Authors: Dulo Olena A. , Furman Yurii M. , Maltseva Olha B. , Samoilenko Svitlana M.
Published: April 2023

The aim: To determine the aerobic and anaerobic productivity of females from the lowland districts of Zakarpattia region, depending on the component composition of body weight.
Materials and methods: A comparative analysis of physical health status of females in the post-pubertal period of ontogenesis, was carried out. Physical health status was assessed by indicators of aerobic and anaerobic productivity depending on the component composition of the body, which was determined by impedance measurement.
Results: Physical health of females from the lowland districts depends on the component composition of the body, namely: an excellent level of aerobic productivity is observed in females who have a normal body weight with a high relative fat content and a normal relative content of skeletal muscles, VО2 max rel. > 38 ml·min-1·kg-1; as a result, their physical health exceeds the “critical level” according to H.L. Apanasenko and corresponds to “excellent” according to Ya.P. Pyarnat’s criteria. Females from lowland districts who are underweight with a normal relative fat content and a high relative skeletal muscle content have an average level of aerobic productivity, VО2 max rel. < 34 ml·min-1·kg-1; as a result, their physical health is below the “critical level” according to H.L. Apanasenko.
Conclusions: The presence of fat in females from lowland districts provides energy for muscle work, which contributes to better development of the muscular system. A high level of energy supply due to a high relative fat content determines the excellent physical health status of females from the lowland districts of Zakarpattia.
PATIENT MANAGEMENT TACTICS AT DIFFERENT STAGES OF GASTROINTESTINAL STROMAL TUMORS (GIST)
Authors: Hotko Yevhen S. , Zhero Svyatoslav V. , Varga Layosh L. , Rosul Myroslav V.
Published: April 2023

The aim: To analyze the results of treatment even in limited groups of patients.
Materials and methods: Clinical cases of GIST based on the materials of the surgical clinic of the Central Municipal Hospital in Uzhgorod (Transcarpathian region) were discussed. Clinical, ultrasound and CT monitoring was provided. CT dynamics were assessed according to RECIST 1.1.
Conclusions: Only surgery resection is enough in case of the “small” tumor originated from the stomach. Otherwise, in case of locally-widespread GIST it is expedient to refrain from radical surgical intervention. High-grade GIST was verified by the IHC examination with mutation of the KIT gene in exon 11. Imatinib mesylate 400 mg PO daily was prescribed. More than 1-year follow-up result: firstly more than 50% reduction of the tumor size with subsequent stabilization of the disease.
Minimally invasive processes allow surgical interventions and do not require aggressive adjuvant therapy. The presence of a giant GIST is a serious diagnostic and treatment challenge. Only management of the patient by a multidisciplinary team allows to resolve diagnostic and treatment contradictions, to create the prospect of achieving complete or partial remission and long-term survival.
THE INFLUENCE OF SPELEOTHERAPY ON BRONCHI PASSAGE IN CHILDREN WITH BRONCHIAL ASTHMA USING A PHARMACO-FUNCTIONAL TEST WITH SALBUTAMOL
Authors: Bilak Volodymyr M. , Ignatko Lyudmila V. , Sochka Natalya V. , Debretseni Olena V. , Kossey Gabriella B. , Mashika Volodymyr Y. , Griadil Taras I.
Published: April 2023

The aim: To investigate the reaction of the bronchi to inhalation of salbutamol in children with different severity of bronchial asthma under the conditions of speleotherapy.
Materials and methods: 40 children aged 6-15 years were examined, 20 of them had an intermittent course of the disease, 20 had a mild course, and the children were in the inter-relapse period. Determining the function of external respiration (FER) with a pharmaco-functional test (PFT) with salbutamol was carried out in the dynamics of observation before and after treatment and compared with the indicators of 40 healthy children. Speleotherapy was performed based on the children’s department of the Ukrainian Allergological Hospital of the village Solotvino.
Results: A decrease in increased bronchial tone and restoration of bronchial patency at all levels of the bronchi in all patients with an intermittent course of the disease and a partial decrease in bronchial hyperreactivity with the improvement of bronchial patency in children with a mild course of bronchial asthma under the influence of speleotherapy was established.
Conclusions: Thus, speleotherapy contributes to a positive reaction of the bronchi to inhalation of salbutamol, which is reflected in the normalization of disturbed bronchial tone and the restoration of bronchial patency at all levels of the bronchi, in all patients with an intermittent course and partially with a mild course of the disease.
THE DETERMINATION OF HIP CIRCUMFERENCE IN THE MIDDLE OF YOUNG BOYS AND YOUNG GIRLS OF HIGHER EDUCATION INSTITUTIONS OF BUKOVINA DEPENDING ON THE SPORT TYPE
Authors: Karatieieva Svitlana Yu. , Slobodian Oleksandr M. , Muzyka Natalya Ya. , Slobodian Kseniya V. , Kolesnik Oksana V.
Published: April 2023

The aim: To find out the features of the hip circumference in the middle of both extremities by students of higher education institutions of Bukovina, depending on the sport type.
Materials and methods: The study of anthropometric parameters was conducted on 115 students of higher education institutions of Bukovina from 16 to 18 years where 78 (67.82%) – young boys and 37 (32.18%) – young girls. The main group of 75 (65.22%) students were represented by the first and the second year students of the Faculty of Physical Culture and Human Health of the Yuriy Fedkovich Chernivtsi National University, and control group consisted of 40 (34.78%) college students and students of the Stomatological Faculty of Bukovynian State Medical University. Among the students of the main group were – 57 (76.0%) young boys and 18 (24.0%) young girls who, in addition to physical activity, which was included in the program of their specialty, additionally engaged in the sports (football players, volleyball players, basketball players, handball players), the control group consisted of 21 (52.5%) young boys and 19 (47.5%) young girls who are busy with hours of physical education, according to the curriculum of their specialty and did not engage in additional sports. Anthropometric examination included the definition of total (height and body weight) parameters and partial (hip circumference in the middle third). Statistical analysis of the data was performed using a licensed program RStudio.
Results: Based on the Kraskel-Wallis test, it was found that there is a significant difference in the average length of the hip circumference (in the middle third) on the left depending on the sport. Based on the Conover-Iman test, it was found that there is a significant difference for the pairs «basketball» – «handball», «control» – «handball», «football» – «handball», «volleyball» – «control», «volleyball» – «football», «volleyball» – «handball».
Conclusions: The model for predicting the length of the hip circumference (in the middle third) on the right has the form y = β1 + β2 + 0,328 * х1 – 0,167 * х2, on the left it looks like y = β1 + β2 + 0,451 * х1 – 0,179 * х2, where y is the girth of the thigh in the middle third, is the weight, х2 is the height. The coefficient β1 = 58,181 for young girls and β2 = 53,302 for young boys. Coefficient β2 = 0 for the group «basketball», β2 = – 3,358 for the group «control», β2 = – 0,484 for the group «football», β2 = – 1,991 for the group «handball», β2 = – 0,824 for the group «volleyball».
ETHICAL EXPERTISE OF BIOMEDICAL RESEARCH AS A WAY OF HUMAN RIGHTS PROTECTION
Authors: Boldizhar Sandra О. , Nechiporuk Kiril О. , Panov Alen V. , Kopcha Natalia V.
Published: April 2023

The aim: To find out the peculiarities of ethical expertise of biomedical research as a way of human rights protection.
Materials and methods: The dialectical method of cognition, based on the epistemological possibilities of the laws and categories of dialectics, provided a study of the formation and activity of bodies and institutions responsible for the ethical examination of biomedical research. Formal and logical methods of analysis and synthesis made it possible to reveal the meaning of the concepts that make up the subject of the study, to carry out their classification, as well as to formulate intermediate and general conclusions. The systematic method made it possible to investigate the role and significance of biomedical human rights among other human and citizen rights and freedoms. Using the historical method, the main stages of the formation of biomedical research with human participation were determined. The structural-functional method made it possible to clarify the internal structure of the mechanism of constitutional and legal protection of the rights and freedoms of a person and citizen in the process of conducting biomedical research, as well as to determine the functional purpose of each of the elements of this mechanism. The content of legal regulations governing social relations, within which the organization and functioning of the human rights protection mechanism in the process of conducting biomedical research is carried out, was revealed with the help of a special legal method of cognition. The comparativist method made it possible to identify similar features and differences in the constitutional and legal regulation of the mechanism for the protection of human rights in the process of conducting biomedical research.
Conclusions: Despite such a large number and variety of bioethics committees, it is worth noting that today it is not possible to state with certainty the existence of a full-fledged system of interconnected ethical committees, since the existing normative documents on their activities are of a temporary nature, and do not always clearly define the assigned their functions and tasks. In addition, there is an opinion that attempts to bureaucratize the existing situation (establish clear departmental subordination, define vertical and horizontal connections between ethics committees) are highly undesirable. Of course, on the one hand, excessive complication and bureaucratization will not contribute to progressive development in the activities of committees, and the system that has chaotically developed today is also not satisfactory.
KETERKAITAN PASAL RUKUHPIDANA DENGAN CYBER LAW, SEBAGAI PELAKSANA ASAS LEX POSTERIOR DEROGAT LEGI PRIORI
Authors: Rian Rahadian
Published: April 2023

Asas lex posteriori derogat legi priori dengan pengertian bahwa undang-undang baru itu merubah atau meniadakan undang-undang lama yang mengatur materi yang sama. mengatur masalah yang sama dalam hierarki yang sama. Sebagai pembaruan KUHP yang lama, RUU KUHP, akan mulai berlaku setelah tahun terhitung sejak tanggal diundangkan, berdasarkan Pasal 624 KUHP. RUU KUHP ada terkaitan dengan cyber law, sebab Banyak mengatur Aktivitas Kejahatan Cyber, atau Cybercrime.

Kata Kunci: Asas Lex posterior derogat legi priori, Merubah, meniadakan, Pasal 624 KUHPidana, Kejahatan Cyber.

The principle of lex posteriori derogat legi priori means that the new law changes or abolishes the old law which regulates the same matter. organize the same problem in the same hierarchy. As a renewal of the old Criminal Code, the RUU KUHP will come into force after the year from the date of promulgation, based on Article 624 of the Criminal Code. The Criminal Code Bill is related to cyber law, because it regulates a lot of Cybercrime Activities, or Cybercrime.

Keywords: The principle of Lex posterior derogat legi priori, Amend, abolish, Article 624 of the Criminal Code, Cyber Crime.
PEMETAAN SEBARAN KEJADIAN GEMPA BUMI DI PROVINSI PAPUA
Authors: Andika Yusverison , Trianggoro Saputro Imam
Published: April 2023

Provinsi Papua merupakan salah satu provinsi di Indonesia timur. Kawasan bagian timur dari Indonesia memang dikenal memiliki tingkat kerawanan gempa yang tinggi. Gempa dengan intensitas rendah sampai tinggi sering terjadi sehingga berpotensi menimbulkan korban jiwa dan juga kerusakan infrastruktur. Oleh karena itu, diperlukan suatu upaya mitigasi untuk mengatasi hal tersebut. Salah satu upaya mitigasi yang dapat dilakukan yaitu membuat suatu pemetaan terhadap sebaran gempa bumi berdasarkan data kejadian di masa lalu. Dengan adanya peta ini bisa menggambarkan konsentrasi aktifitas gempa bumi yang terjadi di Provinsi Papua. Diharapkan peta ini dapat digunakan sebagai upaya mitigasi dalam rangka pengurangan resiko bencana gempa bumi di wilayah Provinsi Papua. Data kejadian gempa bumi yang digunakan untuk peneltian ini yaitu data gempa yang bersumber dari USGS di wilayah Papua Barat pada periode 1964-2021. Analisis terhadap gempa dilakukan dengan cari declustering yaitu memisahkan antara gempa utama (mainshock) dan gempa susulan (aftershock) yang terjadi. Pemetaan sebaran lokasi gempa dilakukan menggunakan dua klasifikasi yaitu berdasarkan besarnya magnitudo gempa dan kedalaman terhadap pusat gempa bumi. Hasil penelitian menunjukkan bahwa Pada kurun waktu 1964-2021 di Provinsi Papua jumlah kejadian gempa bumi adalah berjumlah 6713 kejadian. Jumlah gempa utama (main shock) yang diperoleh dari hasil analisis declustering adalah 3904 kejadian atau sebesar 58.16% dari jumlah total kejadian gempa yang terjadi di Provinsi Papua pada periode waktu 1964-2021. Gempa bumi yang terjadi di wilayah Provinsi Papua didominasi oleh gempa dangkal sehingga sangat berpotensi merusak.
Designing Critical Multilingual Multiliteracies Projects in Two-Way Immersion Classrooms: Affordances and Impacts on Students
Authors: Hyun Jungwon , Bettney Heidt Esther , Prasad Gail
Published: April 2023

Language separation policies in two-way bilingual education (TWBE) reflect ideologies of double monolingualism (Heller, 1995) and ignore the sociolinguistic realities of bi/multilingual students (García & Lin, 2017). This case study investigates the design and implementation of collaborative multilingual identity text projects (Prasad, 2018) in a Spanish-English two-way immersion (TWI) school. Identity text pedagogies (Cummins & Early, 2011) that engage bilingual students in creating dual-language multimodal texts have been taken up across a wide variety of contexts. Few studies in the United States, however, have examined how TWI teachers can use multiliteracies pedagogy (New London Group, 1996) with a critical multilingual language awareness (CMLA) focus to move beyond the frame of Spanish-English through the creation of collaborative multilingual and multimodal class books. A thematic analysis of classroom data from our case study demonstrates that implementing critical multilingual multiliteracies projects fostered students’ CMLA while building positive bi/multilingual identities, leveraged students’ linguistic repertoires beyond the language of instruction, and encouraged linguistic risk-taking. This empirical study highlights the possibilities for adopting a collaborative, critical, and creative multilingual multiliteracies approach in TWI settings.
Forces et limites d’un dispositif plurilingue pour soutenir l’apprentissage de l’orthographe grammaticale française par des élèves bi/plurilingues
Authors: Maynard Catherine
Published: April 2023

L’apprentissage de l’orthographe grammaticale (OG) française pose de grands défis aux élèves, tant en langue première qu’en langue seconde (Lefrançois et al., 2008). Dans ce contexte, notre étude s’intéresse à l’expérimentation d’un « dispositif plurilingue » d’enseignement de l’OG française auprès d’élèves bi/plurilingues de première secondaire au Québec. Mettant en œuvre une pédagogie du translanguaging (Cenoz et Gorter, 2020; Garcia et al., 2017) et comportant des activités d’éveil aux langues (Auger, 2014), ce dispositif inclut également des dictées métacognitives (Nadeau et Fisher, 2014) et une approche intégrée (Allal, 2018). Des prétests et des posttests (dictées et productions écrites) ont permis d’évaluer les effets du dispositif pour certains objets spécifiquement (accord du verbe, de l’adjectif et du participe passé avec être [PPE], terminaisons verbales en /E/), en comparaison avec un dispositif monolingue et des pratiques habituelles d’enseignement. Il est notamment constaté qu’une force particulière du dispositif plurilingue est d’ancrer les apprentissages dans la durée pour l’accord de l’adjectif et du PPE.
Les tâches intégrées plurilingues nécessitant la compréhension en anglais dans des universités non anglophones : les perceptions et les pratiques déclarées d’étudiants ayant des profils académiques et langagiers variés
Authors: Bell Philippa , Laguë Audrey-Anne , Payant Caroline
Published: April 2023

En contextes universitaires, les étudiants sont souvent confrontés à des tâches intégrées d’écriture qui demandent de la compréhension d’informations afin de produire des textes. Ces tâches académiques complexes ont fréquemment été étudiées comme des tâches unilingues avec des anglophones ou des apprenants de l’anglais étudiant dans des universités anglophones. Pourtant, le développement du savoir scientifique à l’université nécessite souvent la lecture en anglais, peu importe la langue d’enseignement, ce qui rend ces tâches plurilingues dans certains contextes. Plusieurs étudiants d’universités non anglophones se trouvent dans des programmes requérant la lecture d’articles scientifiques en anglais alors qu’ils ne sont pas des apprenants de l’anglais. Pourtant, les expériences de ces utilisateurs sont généralement peu étudiées dans la littérature scientifique actuelle. Pour mieux soutenir cette population étudiante dans le développement de leur littératie académique plurilingue et dans la réussite de leurs études universitaires, il est impératif d'examiner comment les utilisateurs de l'anglais accomplissent des tâches d'écriture plurilingue. Cette étude qualitative répond partiellement à ces préoccupations en examinant les perceptions et les pratiques déclarées de trois étudiants face à une tâche intégrée plurilingue. Les résultats démontrent que les étudiants rencontrent des difficultés différentes en fonction de leurs niveaux de compétence langagière et de leur cheminement scolaire. De futures recherches doivent se pencher sur le rôle des programmes universitaires et des professeurs qui demandent aux étudiants d’accomplir des tâches intégrées plurilingues pour mieux comprendre quelles adaptations sont possibles et souhaitables pour que tous les étudiants aient accès au développement de la littératie académique et disciplinaire.
A Machine Learning Approach for Automated Cost Estimation of Plastic Injection Molding Parts
Authors: Florian Klocker  , Reinhard Bernsteiner  , Christian Ploder  , Martin Nocker
Published: April 2023

Market competition leads to shorter cycle times for new or updated products. Therefore, flexibility in reacting to market changes, product development, and all related processes must be accelerated. In this regard, accurate cost estimation in the early stages of product development is critical for assessing the economic viability of a product. However, cost estimation requires data and expertise from several departments. Machine learning approaches could improve the accuracy and reduce the time needed for cost estimation. To investigate the eligibility of machine learning based cost estimation, a case study was conducted on an industrial company that produces plastic molding parts as key components of its products. The study involved training various supervised machine learning algorithms on a dataset of plastic injection molding parts using three different cost calculation methods. The three methods differed in the extent to which they considered the different process steps involved in the production of the parts. Different tree-based machine learning regression models and neural network models were trained to identify the most suitable approach for cost estimation in the given context. The results showed that tree-based machine learning algorithms outperformed neural networks and that individually predicting manufacturing parameters for cost calculation of each manufacturing process step leads to the most accurate cost estimation. This paper demonstrates how machine learning can support cost estimation in the early stages of the product lifecycle, reducing development times and improving cost estimation accuracy.
Approach of Care among Depression Patients with Coronary Artery Disease: A Literature Review
Authors: Mahendra Agus
Published: April 2023

Patients with coronary artery disease (CAD) frequently experience psychiatric morbidity, such as depression. It's still unknown how pre-existing depression affects mortality in people with coronary artery disease (CAD). The study's overall goal was to discover depression among patients with coronary artery disease. The detection of psychological problems (depression) in individuals with CAD has been proven to improve prognosis and quality of life. Patients who are being treated for depression or anxiety may be more likely to stick to risk factor reduction, recommended medications, and rehabilitation programs. As a result, patients with known CAD and psychiatric illnesses should be assessed.
Sistem Informasi Desa Siaga Pangan Menghadapi Covid19 berbasis Web Service
Authors: Septiani Amanda Putri , Junardi Wira , Amaliah Ainun , Bachtiar Arief , Mahendra JM Ihza , Muttaqin Muhammad Irfan
Published: April 2023

SIDAVID19 is a food alert village information system to deal with COVID19, a capability that must be owned by the system for recording the entry and distribution of staple goods, BKPD can know food supplies and aid recipients in an integrated manner as well as village residents to obtain information to distribute village food via the internet. Information integration is a necessity for the government in realizing integrated services to the public. The SIDAVID19 service is one of the services provided to facilitate the management of the distribution of staple goods during the COVID9 emergency and access to information for the public and BKPD. This study describes the design of the SiDavid19 service, which is a web service technology to connect users and providers in retrieving information needed by users.
Kajian Sistem Deteksi Dini pada saat Pandemi COVID-19
Authors: Setyasaputra Nurmajid
Published: April 2023

One of the increasing cases of COVID-19 is due to the large crowd. The crowd that occurred during the last quarter of 2020 occurred as a result of the easing of the PSBB to revive the community's economy, rife demonstrations, and other activities or events with large numbers of people. This is very worrying, coupled with the limited facilities and health workers to treat COVID-19 patients for those with severe symptoms. Therefore, an early detection system is needed by utilizing existing technology, especially for cities that have implemented smart cities and become red zones. So that this system can be an early warning or early detection for stakeholders to make decisions more quickly to prevent additional cases.