bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of Genotype-Specific Antibody Responses to Glycoproteins B and H in Primary and Non-Primary Human Cytomegalovirus Infections by Peptide-Based ELISA
Authors: Zavaglio Federica , Fiorina Loretta , Suárez Nicolás M. , Fornara Chiara , De Cicco Marica , Cirasola Daniela , Davison Andrew J. , Gerna Giuseppe , Lilleri Daniele
Published: March 2021

Background: Strain-specific antibodies to human cytomegalovirus (HCMV) glycoproteins B and H (gB and gH) have been proposed as a potential diagnostic tool for identifying reinfection. We investigated genotype-specific IgG antibody responses in parallel with defining the gB and gH genotypes of the infecting viral strains. Methods: Subjects with primary (n = 20) or non-primary (n = 25) HCMV infection were studied. The seven gB (gB1-7) and two gH (gH1-2) genotypes were determined by real-time PCR and whole viral genome sequencing, and genotype-specific IgG antibodies were measured by a peptide-based enzyme-linked immunosorbent assay (ELISA). Results: Among subjects with primary infection, 73% (n = 8) infected by gB1-HCMV and 63% (n = 5) infected by gB2/3-HCMV had genotype-specific IgG antibodies to gB (gB2 and gB3 are similar in the region tested). Peptides from the rarer gB4-gB7 genotypes had nonspecific antibody responses. All subjects infected by gH1-HCMV and 86% (n = 6) infected by gH2-HCMV developed genotype-specific responses. Among women with non-primary infection, gB and gH genotype-specific IgG antibodies were detected in 40% (n = 10) and 80% (n = 20) of subjects, respectively. Conclusions: Peptide-based ELISA is capable of detecting primary genotype-specific IgG responses to HCMV gB and gH, and could be adopted for identifying reinfections. However, about half of the subjects did not have genotype-specific IgG antibodies to gB.
Arsenic Removal from Highly Contaminated Groundwater by Iron Electrocoagulation—Investigation of Process Parameters and Iron Dosage Calculation
Authors: Müller Daniel , Stirn Charlotte Nina , Maier Martin Veit
Published: March 2021

Electrocoagulation (EC) is gaining increased attention for water treatment as it efficiently removes various water contaminants. Therefore, EC was applied to remove arsenic from groundwater of a highly contaminated site in Hamburg, Germany. Groundwater containing 3250 and 14,600 µg/L arsenic, mainly as Arsenite (As(III)), was treated in three different EC batch reactors using a monopolar parallel electrode-configuration. This study focused on iron EC with constant current densities and variable voltage, to investigate the influence of current density, surface to volume ratio, initial arsenic concentration and water volume on the removal of arsenic and the influences on the groundwater composition. Arsenic removal >99.9% was achieved for configurations with high iron dosage after four hours of EC treatment. German drinking water standard for arsenic (<10 µg/L) was obtained after around two hours depending on the applied current densities. Arsenic removal efficiency shows independence from current density, surface to volume ratio, initial concentration and water volume, with respect to the calculated iron dosage. Consequently, the dimensioning and regime of efficient operation of the EC reactor for arsenic removal from groundwater can be calculated solely from the iron dosage determined by the applied current.
DESCRIPCIÓN DEL INTENTO SUICIDA EN ARMENIA 2016-2018
Authors: Betancur-Pulgarin Carmen Luisa , Marín-Giraldo María del Pilar , Escobar-Angel Juliana , Marín-Rodríguez Diana Karina , Ortega-Muñoz Laura Isabella
Published: March 2021

Introducción: La incidencia en Colombia del intento de suicidio ha ido en aumento año tras año, siendo el Quindío uno de los departamentos con una tasa de incidencia superior a la del país por lo que se hace necesario la caracterización de la población y la identificación de los factores relacionados con el intento de suicidio en la región.

Objetivo: Describir el intento de suicidio en la ciudad de Armenia durante el periodo 2016 – 2018.

Metodología: Se realizó un estudio observacional descriptivo con un primer intento suicida notificado por el SIVIGILA, se utilizó estadística descriptiva, pruebas de Chi cuadrado y  Mann Whitney.

Resultados: Se analizó una muestra de 598 casos notificados de intento de suicidio donde más del 50% fueron menores de 29 años y según su estado civil el 68,9% se encontraba sin pareja; el estrato socioeconómico predomínate fue bajo, el mecanismo utilizado más frecuente fue la intoxicación. Se encontró relación entre intentos de suicidios previos y enfermedad crónica, problemas jurídicos, antecedente de trastorno psiquiátrico y consumo de SPA. Según el periodo epidemiológico en los años analizados la tendencia fue creciente para los periodos IX y XI.
A Study on the Economic Impact and Preventive Measures about Covid-19 in Tamilnadu
Authors: Sangamithra A , Dhavamani P
Published: March 2021

This paper represents the COVID-19 Economic impact and pandemic that’s affecting our globe widely. The virus is sweeping across the world, parting a trail of efficient and group dent in its wake. Coronavirus has gone with new evils and miseries in the large-scale nation and health. The profitable force of the coronavirus is subsequently critical that the experts predicted that the forthcoming large scale depression would be as like as the 1929 terrible depression or at slightest will cross over the 2008 monetary crisis. Countries adopted a national scale lockdown as a head march to enclose the coronavirus. For that altogether, money-making  behavior and everyday energy stopped, barren cities and the street feels like hollows. The macro monetary brunt of the coronavirus and the outlook of the macro cost-cutting measure after the epidemic ends. Corona infection is increasing rapidly in India and the number of people falling victim to the coronavirus infection. The coronavirus disease continues to increase across humankind next to a path that is tough to predict. The health, caring and socio-economic policies adopted by countries will control the rate and dilution of the recovery. The World Health Organization and health experts and doctors are advising people to be safe to raise awareness.
The Causes of Cancer: An Analysis of Avoidable Risk Factors
Authors: Sangamithra A
Published: March 2021

Recently many new causes of cancer have been recognized, such as Sunlight, tobacco, pharmaceuticals, hormones, alcohol, parasites, fungi, bacteria, salted fish, wood dust, and certain herbs. However, they are additional causes of cancer that contains beta carotene, red meat, processed meats, low intake of fiber diets, poor Exclusive Breast Feeding (EBF), obesity, increased adult height, sedentary lifestyles, etc.; there is a knowledge imbalance in knowing the causes of cancer among the physicians as well as researchers. To prevent at and permit the early detection and effective treatment is necessary in this regard. Steps were taken to prevent, control and management of cancer are disturbed by the insufficient knowledge about the disease among the population. The ultimate aim of cancer management is to reduce the prevalence of cancer and to improve the quality of life. A practical way to identify cancer control risk is to understand the real risk factors for causing cancer. When the causes are not well explained and understood, it is difficult to treat the disease. Screening of asymptomatic populations and awareness of early signs and symptoms can certainly improve the treatment of cancer. Knowing the causes of cancer and knowledge about preventing it can cure the disease, prolong our life, and improve the quality of our life. Cancer research is crucial for effective planning and strategic Cancer Control Programmes (CCP).
An Economic Study on Financial Literacy among Working Women in Madurai City
Authors: Duraichamy J , Ponraj P
Published: March 2021

Financial literacy is a knowledge related to financial instrument. In India women are equally earnable like men as and they financially independent. Financial literacy is an ability to manage and invest money on financial sources. Low financial literacy may cause financial loss in individual’s life which affect family as well. In this study financial literacy among working women has been analysed with the objective to find the financial literacy level among working women and to analyse the most preferred investment instrument. 45 samples were collected from working women over various field like textile industry, Information technology, fashion, teachers, professors and health industry based working women are taken as sample for the study. Data collected with the help of questionnaire, simple random sampling techniques is used for sampling, SPSS soft ware is used to analyse data.
Infrared spectroscopy in the assessment of the mineral composition of kidney stones
Authors: Kolupayev S.M. , Lesovoy V.N. , Bereznyak E.P.
Published: March 2021

As a result of infrared spectroscopy of kidney stones obtained from 59 patients with urolithiasis, a wide range of chemical compounds were identified in the samples, in which whevellite (calcium oxalate monohydrate), hydroxylapatite and uric acid were presented in the largest quantities. Monophasic stones were found in 8.4 % of patients. The two-phase, three-phase and four-phase composition of the samples was determined in 37.2 %, 42.3 % and 11.8 % of patients respectively. Carrying out infrared spectroscopy of kidney stones obtained as a result of self-passage or due to the use of surgical methods will contribute to the correct choice of an individual program for metaphylaxis of urolithiasis in different patients.
Factors that cause caries among children. Current state of question
Authors: Godovanets O.I. , Kotelban A.V. , Grinkevich L.G. , Romanyuk D.G.
Published: March 2021

The review of the literature considers the current understanding of scientists about the risk factors for the development of diseases of hard dental tissues in children. Dental caries is an important social problem of childhood in all countries of the world. The worldwide prevalence of this disease ranges from 25 % to 72 %. While, according to the WHO, the frequency and intensity of dental caries in children have been declining in a number of countries in recent decades, in Ukraine these rates remain high and tend to increase. Caries of temporary teeth ranks tenth among the most common diseases in the world. It is a multifactorial, diet-associated dental disease manifested by foci of demineralization. The etiology and pathogenesis of dental nosology are well studied and known. Despite this, tooth caries remains an important social problem among children in all countries of the world, and is often accompanied by serious impacts on the health of children and their families.
Iamblichus’ Response to Aristotle’s and Pseudo-Archytas’ Theories of Time
Authors: Trostyanskiy Sergey
Published: March 2021

This article aims to shed light on certain aspects of Iamblichus’ theory of time that have not been sufficiently examined to date in the scholarly literature. As of today, there are a mere handful of scholarly works tackling Iamblichus’ solutions to the paradoxes of time in particular, and his contribution to the developments of the Neoplatonic theory of the subject more generally. This article attempts to redress the lack of literature on this topic by examining Iamblichus’ response to Aristotle’s and Pseudo-Archytas’ theories of time. It begins with a brief survey of the philosophical developments that led to and were formative for Iamblichus’ philosophical explorations of the area in question. Then it moves on to provide a detailed account of Iamblichus’ own unique and puzzling theory of time. The author applies the method of comparative analysis, scrutinizing Iamblichus’ solution to the paradoxes of time against the backdrop of Aristotle’s and Pseudo-Archytas’ theories. The author identifies firm scholarly grounds for doing so from within the tradition of Iamblichus studies initiated by the ground-breaking research of Shmuel Sambursky and Salomon Pines and continued, inter alia, in the subtly nuanced analysis of Richard Sorabji and John Dillon. The author concludes that Iamblichus successfully resolved the paradoxes of time and that his conception lent itself to a more effective highlighting of the ordering function of time.
A New Image Completion Method Inserting an Image Generated by Sketch Image
Authors:   Department of Electronics and Communications Eng, Kwangwoon Univ, Seoul, Korea., Ko Hyung-Hwa , Choi GilHee ,   Department of Electronics and Communications Eng, Kwangwoon Univ., Seoul, Korea., Lee KyoungHak ,   IACF, Kwangwoon Univ, Seoul, Korea.
Published: March 2021

Recently, many studies on the image completion methods make us erase obstacles and fill the hole realistically but putting a new object in its place cannot be solved with the existing Image Completion. To solve this problem, this paper proposes Image Completion which filled a new object that is created through sketch image. The proposed network use pix2pix image translation model for generating object image from sketch image. The image completion network used gated convolution to reduce the weight of meaningless pixels in the convolution process. And WGAN-GP loss is used to reduce the mode dropping. In addition, by adding a contextual attention layer in the middle of the network, image completion is performed by referring to the feature value at a distant pixel. To train the models, Places2 dataset was used as background training data for image completion and Standard Dog dataset was used as training data for pix2pix. As a result of the experiment, an image of dog is generated well by sketch image and use this image as an input of the image completion network, it can generate the realistic image as a result.
Automatic Diabetic Retinopathy Diagnosis using Prewitt Edge Detection Color Mapping from Fundus Imaging
Authors:   Department of Electronics and Communication, University Institute of Technology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, (M.P), India., Deshmukh Megha , Nigam Dr. Vineeta Saxena ,   Department of Electronics and Communication, University Institute of Technology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, (M.P), India.
Published: March 2021

Diabetic Retinopathy is a diabetic disease that directly affects the vision that causes damaged blood vessels at the back end of the eyes. It a complicated disease that cannot be recognized from normal eyes; a fundus imaging can reflect the impairments over the retina that causes partial or complete blindness that cannot be cured. It is mandatory for a routine examination that may lead to prevent from complete blindness because it can be prevented from current damaged blood vessels but it cannot be revert or treated. In the field of image processing; various diseases can be diagnosed automatically that saves humans life along with easiness for medical professionals. If a person pertains diabetes for a long time may have highest possibility for diabetic retinopathy. Here, the system has been proposed that can diagnose this disease with high level of accuracy with minimal false alarm rate. System uses Prewitt Edge Detection and Color Mapping techniques for recognizing diabetic retinopathy symptoms or damaged blood vessels from fundus imaging. Prewitt is highly sensitive for extracting impairments along with blood vessels and system is able to mask the unwanted area by using color correction tool.
Collaborative Business Intelligence A Case Study of the Dubai Smart City Strategy
Authors:   Hamdan Bin Mohammed Smart University, Dubai, UAE., El Khatib Mounir M. , Alzouebi Khadeegha ,   Hamdan Bin Mohammed Smart University, Dubai, UAE.
Published: March 2021

This study investigates the concept of Collaborative Business Intelligence in general and specifically in three Dubai governmental entities, which are a part of Dubai Open Data Committee: namely Smart Dubai, Dubai Municipality and RTA, in an attempt to improve collaborative Business Intelligence between the three entities thorough a Smart City Project. A qualitative approach was used to collect data. Secondary data derived from academic articles, scholarly literature formulate the literature review and understand the concepts of business intelligence, collaborative business intelligence in general and how such business intelligence works at the three entities in specific. In addition, primary data was derived from interviews conducted with three senior employees from the top management of Smart Dubai, Dubai Municipality and RTA to help further gain in-depth understanding on how the three entities are collaborating with one another in Smart City Project. The results of the study have revealed that all three entities; Smart Dubai – Dubai Data Establishment, Dubai Municipality, and RTA are adopting business intelligence and collaborative BI. In addition, it is evident that the three entities are sharing data through Dubai Pulse for Smart City Projects. As well, the most used systems and software for analyzing and sharing data among all government entities to support decision-making process. The massive volume of data collected from different source required a huge investment in technology, process and people. In addition, because smart city project is still a new project under implementation and reconstruction, the project has reported few challenges with the implementation of BI, collaboration, and integration within the Municipality, RTA, and Smart Dubai, the key challenge is problem is with raising awareness among personnel and individuals working within in these three entities areas to embrace smart services, typical of collaborative business intelligence. As well as privacy and data security in which Dubai Data Establishment has adopted many strategies and policies to improve. Moreover, Limited research on best practice of BI and collaborative BI in UAE based organizations make it difficult to confirm if the organizations achieve the successful implementation of the collaborative BI and that make this assumption an area for further study.
A Serverless FaaS-Architecture: Experiences from an Implementation in the Core Banking Domain
Authors: Kohler Jens
Published: March 2021

The goal of this paper is to analyze experiences
from a FaaS-based cloud native implementation of an ETL
process based on AWS Lambda functions. Therefore, the actual implementation is outlined and the experiences from that
implementation are evaluated. This results in an overview of
pros and cons of a cloud native implementation in general and
determines best practices for other implementations in other
cloud environments or business domains.
New stability conditions for a class of nonlinear discrete-time systems with time-varying delay
Authors: ELMADSSIA SAMI , SADAAOUI KARIM
Published: March 2021

The problem of stability analysis for a class of nonlinear discrete time systems with time varying delay is studied in this work. Such systems are modeled by delayed difference equations. Subsequently, this system is transformed into an arrow form matrix representation. Using M-matrix properties, novel sufficient stability conditions are determined. It is shown how to use our method to design a state feedback controller that stabilizes a discrete time Lure system with time varying delay and sector bounded nonlinearity. The originalities of our findings are shown in their explicit representation, using system’s parameters, as well as in their easiness to be employed. The obtained results demonstrate also that checking stability of a nonlinear discrete time systems with time varying delay can be reduced to an M-matrix test. Several examples are provided to show the effectiveness of the introduced technique.
A Secure Optimization Algorithm for Quality-of-Service Improvement in Hybrid Wireless Networks
Authors: S Smys , Haoxiang Wang
Published: March 2021

Various industrial, scientific and commercial processes involve wireless mesh networks in the recent days. These technologies improve communication technology to a large extent which has led to an increase in utilization of these systems in various fields. In application with intense and complex data flow, improving the quality of service (QoS) has been a challenge and a focus of research leading to more advanced wireless communication systems. This paper provides a novel optimization algorithm for improving the QoS in hybrid wireless networks while preventing malware and routing attacks. The concept of QoS and hybrid wireless networks are examined at the initial stage. Further, the algorithm for optimizing the service quality in the network is proposed accordingly. The ability of data transfer is benefited by data packets in this algorithm. Load distribution is performed such that overcrowding is prevented and information routing is done efficiently though the nodes. Delay or routing is created and control messages are sent for withholding data when certain nodes are overcrowded. This reduces the delay created by overcrowding by 50% while maintaining the permittivity.
Depression in modern phsycology: Study in the light of Islam
Authors: Khan Wajahat , Al-Rehman Dr. Khalil
Published: March 2021

Immense sadness is called depression which is a common and serious mood disorder affecting 121 million people worldwide. It affects thoughts, feelings, behaviors, physical health and social life of a person. Depressed person overwhelms with sadness, loses interest in life and feels difficulty in making decisions. Brain chemistry, genetics, social and environmental factors may cause depression. Antidepressants and talking therapies are major treatment of depression.  Islam is a true religion on the earth, which covers all aspects of life, bridges gap between spirit and matter, balances between individualism and collectivism. Fundamentals of Islam help in prevention and treatment of depression. A true Muslim believes in oneness of Allah almighty, he believes that Allah almighty alone runs all affairs of universe, considers life as a place of trials and tribulations, remains patient in difficulties of life, his heart is peaceful with the remembrance of Allah, he puts trust in Allah almighty, whenever he commits sin repents, seeks forgiveness from Allah almighty for his sin.
REFORM THROUGH TRADITION: AN ANALYSIS OF YUSUF AL-QARADWI’S APPROACH TO HALAL AND HARAM
Authors: Akram Munazza
Published: March 2021

The concept of permissibility (?al?l) and impermissibility (?ar?m) claims a central place in the Islamic ethos. Muslims are always conscious about the permissibility of whatever they commit or omit in their daily lives, be it in public or private spheres. The level of this consciousness is even higher when it comes to the matter of food. The bewildering range of edible materials and seemingly countless recipes in today’s food market present a formidable challenge for Muslim jurists (fuqah?) in dealing with the issue of permissibility. Among, Y?suf al-Qara??w? is one of the contemporary scholars who have addressed this issue in the context of today’s challenges. This paper discusses al-Qara??w?’s reformative approach to ?al?l and ?ar?m with especial reference to the matters related to food. The paper analyses how al-Qara??w? interprets the relevant Qur’anic verses and the Prophetic traditions (ah?d?th) and attempts to unearth the underlying juristic principles that he relies on for his particular opinions. Also, the paper compares his interpretive strategies with those of the classical jurists. Theoretically, the paper revisits al-Qara??w?’s approach and frames it with reference to Fazlur Rahman’s classification of different reform strategies in Islam. In this light, the article concludes that al-Qara??w?’s approach seems to be what Fazlur Rahman calls ‘reform through tradition.
Contemporary Ideality of Sunnah al-Tarkiyah and unity of the Muslim Ummah: Research Study
Authors: Khalid Muhammad Usman , Hassan Dr. Muhammad Shahbaz
Published: March 2021

This research eradicates the motives of innovation in the acts and deeds of Muslim Ummah. The un-islamic and unlawful additions are going to destruct the Ummah day by day. Innovation in its sense, has no more importance, but its pioneers are spreading it. All the disputes at last has roots in these innovations. Muslim ummah remained united until or unless innovations intermingled. As era went far off from the Nabwi era, the real sense of religion being vanished. As 14th century A.H. came nobody is there to prove innovations as no more part of Islam. Followers of innovation are increasing day by day and there are minority of Muslims left who want to get rid of it. Majority is serving his energy to prove that innovations are part of Islam. Secondly, they find its roots from Nabwi era which is useless. Thirdly, they wrongly proving its reward in this world and hereafter. Major objective of this research is to intimate all such acts and deeds which are wrongly now going to be the part and parcel  of Shari’ah, as well as be the part of our legislation. Such kind of all deeds and actions must be condemned and discouraged for the sake of unity peace and sovereignty of the Muslim world.
The Concept of State intervention in economic Affairs: study of Islamic Injunctions
Authors: Ashraf Maria , Zahid Dr. Abdul Rouf
Published: March 2021

Islam is a Religion in line with nature. It introduced its own economic system that up to the man’s needs and requirements. It contradicts the communism and capitalism and claims that Islamic economic structure guarantees the welfare of humanity. In this setup, the buyers and sellers are free to make their deals and every person has the equal opportunities to be a wealthy and prosperous trader. Muslims had implemented this system in their golden era and showed the benefits of this setup to world The basic question has been raised either state has authority to interfere the economic deals, why state is interested to involve or what would be the limits of their involvement.  In this paper Descriptive Method and Comparative Study are used to study the concept of interference of state in economic matters. This research paper is an effort to understand the Islamic point of view that to what extent the Islamic State can interfere in economic policies, according to the Islamic injunction. In this article, it has been elaborated that the State has the legal and ethical right to intervene the economic matters when hoarding usury and gambling is rampant.
Tendency of Calligraphers regading Quran in Modern Era: Samples of Calligraphers in Punjab, Pakistan
Authors: Tariq Mehmood Dr. Muhammad , Al-Haq Dr. Zia
Published: March 2021

This study intended to highlight the precious art of calligraphy in modern era. Calligraphy is the art of beautiful handwriting. According to Islam calligraphy is the writings of Holy Quran in different letters and styles. It is an ancient and artistic practice in cultural heritage. This study reviewed the writings of different calligraphers of Punjab province (Pakistan). Among the large number of calligraphers only 18 renowned calligraphers were selected to this study. All of the selected calligraphers are well recognized due to their art and work. These manuscripts are kept and visually displayed not only in different museums of Pakistan but across the world also. This study highlighted their masterpieces according to the letters and styles of writings. This study also provided the information about the start of calligraphy and its evolutionary stages.
Mathematical model of determining the index of fractal structures for estimating efficiency of probiotic fodder additives for microbiotes of the gut intestin
Authors:   Candidate of Technical Sciences, Head of the Bioinformatics and Mathematical Modeling Group, Federal State Budget Scientific Institution All-Russia Research Institute for Agricultural Microbiology RAS, Saint Petersburg, Russian Federation, Vorob'ev N. I. , Nikonov I. N. ,   Candidate of Biological Sciences, Associate Professor of Pet Hygiene and Poultry A.K. Danilova, Federal State Budgetary Educational Institution of Higher Education “Moscow state Academy of Veterinary Medicine and Biotechnology – MVA by K.I. Skryabin”, Moscow, Russian Federation, Selina M. V. ,   Candidate of Pedagogical Sciences, Associate Professor of the Department of Information Technologies, Mathematics and Physics, hands. Project Management Sector of the Research and Development Department, Federal State Budgetary Educational Institution of Higher Education “Moscow state Academy of Veterinary Medicine and Biotechnology – MVA by K.I. Skryabin”, Moscow, Russian Federation
Published: March 2021

The work is devoted to the study of the self-organization of microbial communities in the intestines of chickens in different conditions of keeping and feeding chickens and the development on this basis of a mathematical model for determining the index of fractal structures to assess the effectiveness of probiotic feed additives on the microbiota of the intestines of chickens. The experience with chicken diets showed that the level of self-organization of microbial communities in the intestines of chickens depends on the probiotics used. The best indicator of the organization of the microbial community is the experimental version with a probiotic based on Lactobacillus fermentum. It was shown that the index values of the fractal structures of microbial communities in the intestines of chickens when using various probiotic preparations for different experimental schemes are as follows: OP1 – 0,292; OP1 + Probiotic 1 – 0,286; OP1 + Probiotic 2 – 0,354 and the developed mathematical model can be used to evaluate the effectiveness of probiotic feed additives on the microbiota of chicken intestines.
Amperometric detection of water-soluble antioxidants in chitosan-based feed additives and in sheep blood serum
Authors:   Junior Researcher, Department of Physiology and Biochemistry of Farm Animals, All-Russia Research Institute of Animal Husbandry named after Academy Member L. K. Ernst, Dubrovitsy, Russian Federation, Savina A. A. , Volnin A. A. ,   Candidate of Biological Sciences, Researcher of the Department of Physiology and Biochemistry of Farm Animals, All-Russia Research Institute of Animal Husbandry named after Academy Member L. K. Ernst, Dubrovitsy, Russian Federation, Bogolyubova N. V. ,   Candidate of Biological Sciences, Head of the Department of Physiology and Biochemistry of Farm Animals, All-Russia Research Institute of Animal Husbandry named after Academy Member L. K. Ernst, Dubrovitsy, Russian Federation, Voronina O. A. ,   Candidate of Biological Sciences, Veterinary Doctor, Senior Researcher of the Department of Physiology and Biochemistry of Farm Animals, All-Russia Research Institute of Animal Husbandry named after Academy Member L. K. Ernst, Dubrovitsy, Russian Federation, Zaytsev S. Yu. ,   Doctor of Biological Sciences, Doctor of Chemistry, Professor, Leading Researcher at the Department of Physiology and Biochemistry of Farm Animals, All-Russia Research Institute of Animal Husbandry named after Academy Member L. K. Ernst, Dubrovitsy, Russian Federation
Published: March 2021

The effects of chitosan on various metabolic and digestive processes in the animal body are an important to study because of the production quality for animal nutrition, healthcare, etc. The major known changes in the biochemical parameters of the animal liquids (by chitosan usage as feed additive) are the following: ratio of volatile and fatty acids, content of fat, mineral composition, etc. The aim of this study was to evaluate the total amount of water-soluble antioxidants (TAWSA) of feed additives based on chitosan and high protein concentrate of microbiological synthesis and to assess the effect of these feed additives on TAWSA values of sheep blood serum by amperometric method. Firstly, the antioxidant activity of feed components based on chitosan or/and a high-protein microbiological synthesis concentrate was studied in this work. Second, the experiments are carried out on 6 fistula animals to confirm the results of laboratory studies. Third, the determination of the total antioxidant activity of sheep blood by using chitosan additives (as the feed components) by amperometric method was carried out. A particular difference in antioxidant activity of the control and experimental samples of the sheep blood was established for the first time.
Terjemahan Aforisme dalam Karya Tuan Gatsby
Authors:   Universiti Sains Malaysia, Che Omar Hasuria , Kahar Ummi Umairah ,   Universiti Sains Malaysia
Published: March 2021

The novel the Great Gatsby (1925) remains one of the most sought-after classic novels among avid readers to date, whose popularity opened the door for the production of a Malay translation, titled tuan Gatsby (1988). This masterpiece is made up of diverse literary devices and poetic language which demonstrate the original author’s creativity. Among the literary devices present in this well-known work are aphorisms. This term refers to the expressions of differences and similarities in a message, such as idioms, simile, and satire. Aphorisms, however, are rhetorical devices that are rarely discussed by scholars in Malaysia. For this reason, this study was conducted to focus on the translation of aphorisms by comparing the original and translated text. The objectives of this study include identifying the types of aphorisms found in the original work and subsequently assessing the translation of aphorisms in the target text. Besides this, the present study also evaluates the translation approach used by the translator. Based on the analysis conducted, there are six particular types of aphorisms found in the source text which are: aphorisms that hint at a character, confessional aphorisms, metaphorical aphorisms, aphorisms that tease a commonplace, aphorisms that tease out cultural assumptions and aphorisms that hint at questions, as mentioned in Angel-Lara’s research (2015). The findings also show that the translation of aphorisms in the target text successfully convey the aesthetic value of the source text. This is due to the fact that dynamic equivalence, as introduced by Nida (1964), was used as the main approach in the translation of the text under study.
Factors Influencing Food Consumption among University Students
Authors: Sulaiman Yaty , Mohamad Zhariani Sehu , Ismail Mohd Yusri Shahril
Published: March 2021

Vegetables and fruits are an important food component of a healthy lifestyle as it contains variety of nutrients. Ministry of Agriculture and Agro-based Industry Malaysia has showed in the AgroFood Statistics Book 2014 that the commodity consumption of vegetables and fruits kilograms per year from 2008 to 2014 has consistently increase and expected to increase. Studies on factors influencing the consumption of vegetables and fruits are still lacking in Malaysia. There appears to be relatively scarce research and analysis concerning Malaysia. Research aims to identify the attitude of having fruits and vegetables among students of University Utara Malaysia (UUM) by adopting product, price, promotion, place and knowledge as variables. Data were collected using the questionnaire method studied using the Statistical Package for Social Science (SPSS) version 22.0 application. Research was done to examine whether marketing mix factors, product, price, distribution, and knowledge affect the attitude of fruit and vegetable consumption among Universiti Utara Malaysia students. Findings indicates all the variables are significant except for knowledge on vegetables and fruits consumption. Hence, the accuracy of food intake in terms of the amount and the types of food consumed should be aware by the students.
The significance of clinical and hormonal-metabolic parameters in the preoperative prediction of the risk of lymphogenous metastasis in patients with stage I endometrial cancer
Authors: Kishkina Anastasia , Yunusova Natalia , Kolomiets Larisa , Kolegova Elena , Kondakova Irina
Published: March 2021

In patients with moderately differentiated endometrial cancer with less than half myometrial invasion, there are no specific indications for performing or not performing lymphadenectomy. Given the high prevalence of metabolic syndrome (MS) among patients with endometrial cancer (up to 62%) and a large proportion of G2 tumors in combination with MS, the anthropometric and hormonal-metabolic parameters were considered for predicting the risk of lymphogenous metastasis. To build a model of preoperative prognosis of lymphogenous metastasis, the method of logistic regression was used. Data on 53 patients with stage I endometrial cancer was analyzed.  All patients underwent total laparoscopic hysterectomy with bilateral salpingo-ovariectomy and pelvic lymphadenectomy. Positive lymph nodes were found in the surgical specimen of six patients. The additional risk parameters for lymphogenous metastasis were revealed in patients with stage I endometrial cancer, namely: leptin level (AUC = 0.957), visfatin level (AUC = 0.918), body mass index (AUC = 0.911), patient age (AUC = 0.828), and  HDL cholesterol (AUC = 0.699). In addition to traditional risk factors (the depth of invasion and tumor differentiation grade), the model of preoperative prediction of the risk of lymphogenous metastasis for patients with intermediate- risk stage I endometrial cancer included  the following parameters: age, body mass index, HDL cholesterol, level of adipose hormones leptin and visfatin in blood plasma.. The sensitivity and specificity of the model were 83.3% and 97.9%, respectively.
Pathophysiological justification of the use of photodynamic therapy in the initial stage of squamous cell skin cancer
Authors: Masljakov Vladimir , Grebnev Dmitry , Kim Larisa
Published: March 2021

The work is based on an analysis of the course of the disease in 185 patients with squamous cell skin cancer. The study program included studies in three major groups. The first included 74 (40%) patients who underwent combined treatment: an operation involving widespread excision of a tumor under intravenous anesthesia + photodynamic therapy (group 1). The second group was 111 (60%) patients with squamous cell carcinoma of the skin who received only operative treatment. To control and compare the obtained laboratory indicators, a second group was created, which included patients without established pathology. This group included 17 people who voluntarily agreed to conduct the study. The study traced the dynamics of changes in hemostasis scores and metalloproteinases in the two groups being compared. In the group of patients with squamous cell skin cancer, there was a statistically significant decrease in the metalloproteinase-1 inhibitor index, which led to an increase in all metalloproteinase-2, -7 and -9 indicators. Performing surgical treatment did not lead to correction of these indicators, both in the near and distant periods after treatment. The mechanism of influence of photodynamic therapy in squamous cell skin cancer can be characterized as follows: there is a decrease in the inhibitor of metalloproteinase-1, which leads to an increase in matrix metalloproteinases-2, -7 and -9 in the blood, as a result of damage to the endothelium of the vascular wall, which is confirmed by an increase in endothelin, this, in turn, led to the development of vasoconstriction and increased procoagulant activity The use of photodynamic therapy restores the index of metalloproteinase-1 inhibitor, this leads to the restoration of matrix metalloproteinases-2, -7 and -9 in the blood and the prevention of damage to the vascular wall. Comprehensive treatment of patients with squamous cell skin cancer in the initial stage of the disease should include photodynamic therapy with simultaneous intravenous blood irradiation, laser tumor training, and then surgical treatment, consisting in excision of the tumor with observance of oncological principles.
Distance Learning during the Covid-19 Pandemic: Organizational and Psychological Issues
Authors: Леонова Ж.К. , Белоус Е.Н. , Ляпин А.С. , Савельева С.С.
Published: March 2021

Актуальность исследования проистекает из необходимости обобщения опыта масштабного введения дистанционного обучения в связи пандемией коронавируса. Это обстоятельство поставило перед образовательными организациями ряд вопросов, которые требуют научного обобщения и анализа. Авторы отмечают, что по мере расширения технических
и методических возможностей образовательных организаций усиливается тенденция значимости дистанционных технологий в системе образования в целом. При реализации дистанционного обучения выявлены организационные и психологические проблемы, к наиболее очевидным из которых можно отнести следующие: отсутствие стандартов дистанционного образования, проблема авторских прав на учебные и учебно-методические материалы, возможности студентов и преподавателей по приобретению необходимого оборудования для дистанционного обучения, ослабление чувства корпоративного единства у участников образовательного процесса и др. Наряду с организационными, правовыми и социальными вопросами, имеют место и проблемы психологического характера.
В статье рассмотрены результаты анкетирования преподавателей, студентов и их родителей по результатам дистанционного обучения в условиях пандемии коронавируса.
Исследование проводилось в дистанционном режиме с использованием гугл-форм; количество участников — 161 человек.
По мнению авторов, обобщенные результаты данного исследования могут послужить некоторыми ориентирами в процессе применения дистанционных форм обучения в вузе.

The relevance of the research is accounted for by the necessity to generalize the experience of large scale distance learning introduced because of the covid-19 pandemic. The pandemic has made educational organizations face a number of issues which should be analyzed and generalized. The authors maintain that the role of distance-learning technologies increases alongside the enhancement of technological and methodological capacity of educational organizations. Distance learning reveals a number of organizational and psychological problems, the most obvious of which are the following: absence of standards of remote learning, problems associated with copyright for e-textbooks and other learning materials, students’ and teachers’ purchasing power (when it concerns supplies for remote learning), reduced sense of corporate unity, etc. The authors maintain that the participants of remote learning experience problems of organizational, legal, social and psychological character.
The article analyzes the results of a survey of teachers, students and their parents focusing on their perception of distance learning during the covid-19 pandemic.
The survey was conducted online (google-forms) and involved 161 participants.
The authors maintain that the generalized results of the research can be used as guidelines for further implementation of distance learning in universities.
Cultura escolar da Educação de Jovens e Adultos de Florianópolis (SC): a reunião de planejamento na pesquisa como princípio educativo
Authors: Scherer Júnior Claudio Roberto Antunes
Published: March 2021

A Educação de Jovens e Adultos (EJA) da cidade de Florianópolis (SC) funciona tendo a Pesquisa como Princípio Educativo (PPE). Isso representa uma série de mudanças nas formas de compreensão e nas práticas dos professores que trabalham nesse contexto específico. Por meio, principalmente, da categoria de cultura escolar, conceituada através dos trabalhos de Julia (2001) e Viñao Frago (2006), este artigo tem por objetivo apresentar, descritivamente, algumas características de um momento inerente ao funcionamento da EJA em Florianópolis: a reunião de planejamento. Para isso foram utilizadas metodologias de pesquisa do tipo etnográfica com observações de campo e metodologias de história oral em que foram entrevistados os professores que atuavam nesse contexto. Como conclusão dessa pesquisa é possível afirmar que as reuniões de planejamento, tal como são concebidas na EJA de Florianópolis, proporcionam de forma institucionalizada um momento raro de trocas e diálogos entre professores, isso gera resultados positivos para o trabalho dos docentes e torna possíveis as ações educativas com os estudantes via PPE.

Palavras-chave: Educação de jovens e adultos. Cultura escolar. Pesquisa como princípio educativo.
Automated Dispensing Cabinet Optimization in a Level 2 Trauma Center
Authors: Vu Tony , She Yifan
Published: March 2021

Introduction
Opportunities have been identified regarding timely delivery of medications due to lack of ADC inventory related to stock outs or other variances in pharmacy workflow (i.e. compounding and distribution times). These opportunities for improvement impact patient care and result in both nursing and pharmacy staff frustration. Additionally, there are significant costs associated with unused medications stored in ADCs, taking up valuable real estate that would otherwise house more opportune inventory. This situation has created a need for more efficient management of the ADC inventory. Currently, research in the topic area is sparse. We hypothesize that the systematic management and oversight of ADC inventory will demonstrate a significant improvement in key performance indicators and provide insight to the current gaps in knowledge.
Methods
This study will be a continuous quality improvement project with a combination of retrospective data review and prospective optimization interventions of automated dispensing cabinets (Pyxis®). Interventions include review and adjustment of ADC par levels, removal of unused/stagnate medications, standardization of stock, and continual review of ADC inventory turns and associated optimization opportunities. The primary outcomes are the change in vend/fill ratio from baseline, change in medication stockout percentage from baseline.
Results
There was no significant difference in vend/fill ratio after the optimization phase compared with baseline [Difference 0.13 (11.56 ± 6.1 vs. 11.43 ± 5.41) respectively, (p=0.84)]. Medication stockout percentage was also found to be similar with baseline [Difference -0.05 (0.71% ± 0.12 vs. 0.76% ± 0.08) respectively, (p=0.37)]. For secondary outcomes, the change in blind stockout percentage from baseline was -0.04 [0.13 ± 0.02 vs. 0.17 ± 0.02, (p=0.004)] and the change in medications dispensed per day from baseline was 317 [2656 ± 143 vs. 2339 ± 200, (p=0.0002)].
Conclusion
Optimization of automated dispensing cabinets yielded marginal improvements in vend/fill ratio and stockout percentage and significantly improved overall efficiency through an increase in the number of medications stocked in ADCs and number of medications dispensed per day from ADCs. Evaluation of more clinically significant performance indicators may better characterize the benefits from the optimization process.