bluuebunny/crossref_metadata_2025 huggingface dataset:
The SEK-1 p38 MAP Kinase Pathway Modulates Gq Signaling inCaenorhabditis elegans
Authors: Hoyt Jill M , Wilson Samuel K , Kasa Madhuri , Rise Jeremy S , Topalidou Irini , Ailion Michael
Published: July 2017

Gq is a heterotrimeric G protein that is widely expressed in neurons and regulates neuronal activity. To identify pathways regulating neuronal Gq signaling, we performed a forward genetic screen in Caenorhabditis elegans for suppressors of activated Gq. One of the suppressors is an allele of sek-1, which encodes a mitogen-activated protein kinase kinase (MAPKK) in the p38 MAPK pathway. Here, we show that sek-1 mutants have a slow locomotion rate and that sek-1 acts in acetylcholine neurons to modulate both locomotion rate and Gq signaling. Furthermore, we find that sek-1 acts in mature neurons to modulate locomotion. Using genetic and behavioral approaches, we demonstrate that other components of the p38 MAPK pathway also play a positive role in modulating locomotion and Gq signaling. Finally, we find that mutants in the SEK-1 p38 MAPK pathway partially suppress an activated mutant of the sodium leak channel, NCA-1/NALCN, a downstream target of Gq signaling. Our results suggest that the SEK-1 p38 pathway may modulate the output of Gq signaling through NCA-1(unc-77).
Whole Genome Sequence of the Heterozygous Clinical Isolate Candida krusei 81-B-5
Authors: Cuomo Christina A , Shea Terrance , Yang Bo , Rao Reeta , Forche Anja
Published: July 2017

Candida krusei is a diploid, heterozygous yeast that is an opportunistic fungal pathogen in immunocompromised patients. This species also is utilized for fermenting cocoa beans during chocolate production. One major concern in the clinical setting is the innate resistance of this species to the most commonly used antifungal drug fluconazole. Here, we report a high-quality genome sequence and assembly for the first clinical isolate of C. krusei, strain 81-B-5, into 11 scaffolds generated with PacBio sequencing technology. Gene annotation and comparative analysis revealed a unique profile of transporters that could play a role in drug resistance or adaptation to different environments. In addition, we show that, while 82% of the genome is highly heterozygous, a 2.0 Mb region of the largest scaffold has undergone loss of heterozygosity. This genome will serve as a reference for further genetic studies of this pathogen.
FEAR PHENOMENON IN EXISTENTIAL PHILOSOPHY
Authors: Melnyk V. V.
Published: July 2017

Introduction. The article describes the fear in the human consciousness as natural and constructive psychological phenomenon indicating an objectless world. The author makes a conclusion as for empirical isolation of the fear determination in the applied psychology and its narrow phenomenological interpretation as well. Person`s attitude to fear is still one of the urgent and key issues in psychoanalytic and philosophical science. Reflection on the fear term and mode is the underlying foundation for existential and metaphysical understanding of the fundamentals of life. Motivational human activity is governed by fear, which concerns new space and time, loneliness, God and transcendent. The feeling of fear is presented in each living being, but in a great extent it is presented in a man with thin mental organization. Purpose. The article analyzes the fear as the integral phenomenon. Methodology. The fear is described as emotion which is important to avoid dangers, so the author used hermeneutical methodology and anthropological integrative approach while doing the research. Originality. The fear is interpreted here as a result of direct physical stimulation of biological reactions within the human body in response to external stimuli (real or imaginary). The fixation of the fact that fear does not inhibit, but rather activates human activities is an important in socio-theosophical interpretations of fear. The author emphasizes that the fear is objectified in the culture and is amenable to the mechanism of minimization. Great attention is paid to the provocation of the depression by fear. The depression is also interpreted as adaptive form of behavior which in its turn allows a weak person to save power and prevent possible conflicts. Conclusions. Thus fear as the modus is considered to be the way of understanding the origin of entity indicating not its substantial meaning but its peculiar «Ontological intensity».
GENDER EQUALITY AS A MODERN PHENOMENON
Authors: Storozhuk S. V. , Hoyan I. M.
Published: July 2017

Purpose of the work. Forming the axiological system of Western society, with the intentions to establish gender equality as a guarantee of a just society being taken into account, on the one hand, and preserving the traditional gender stereotypes inherent to patriarchal gender roles in a considerable part of the world, on the other hand, is actualizing the study of the factors that have contributed to realizing the problem of gender inequality and discrimination. Therefore, the purpose of our study is to highlight the factors that stipulated the awareness of gender equality in European social and cultural space, while leaving alive the traditional gender values in a number of other cultural environments. Methodology of the study is determined by interdisciplinary approach involving the use of general scientific methods such as analysis, synthesis, generalization, etc. The leading role belonged to the principle of the historical and logical unity. At the same time the study applies the basic principles of philosophical hermeneutics and the contextual analysis method. Originality lies in putting forward the new theoretical statements aimed to show that in the ancient and pre-modern society, gender inequality and discrimination did not exist, because at that time gender relations were considered either as a result of the biological characteristics of a human body, or were explained by worldview ideas about the origin and structural features of the world, prevailing in a specific historical dimension. Consequently, gender roles were taken for granted and were not subject to any doubt. Conclusions. Despite all the worldview shifts that had been taking place in the pre-modern era social outlook, nevertheless, as history has shown, they failed to generate sufficient philosophical foundations either for recognizing the equality of women, or changing their social, legal and political status. This led to accumulating the unconscious internal resistance to dominant social standards, which was expressed primarily in behavioural arbitrariness that, whatsoever had not been acquiring any openness by the beginning of industrialization. The latter, having destroyed rural communities with their inherent division of labour and lifestyle, which eventually weakened significantly the mythological social structures, has opened an opportunity not only to understand but also to commence the fight for the recognition of gender equality.
Nanoparticles as curing and adhesive aid for biobased and petrobased polybenzoxazines
Authors: Monisha  , Shukla Swapnil , Lochab Bimlesh
Published: July 2017

Alumina nanoparticles were incorporated in blends of benzoxazine monomers synthesized from bio- and petrobased phenols, cardanol and bisphenol A, respectively, by way of a one-pot solventless methodology. The structures of the monomers were characterized by proton (1H) nuclear magnetic resonance and Fourier transform infrared spectroscopy. Thermal characterization was performed using differential scanning calorimetry and thermogravimetry. The size of bare alumina nanoparticles and those in the polymer nanocomposite was analyzed by powder X-ray diffraction. Blending of alumina particles resulted in lowering of curing temperature of benzoxazine monomer. The effect of nanoparticle incorporation was reflected in the curing behavior and adhesive properties. The adhesive strength is found to be dependent on whether solution or solventless processing is used and on the weight percent of the nanoparticles in the monomer blend. The replacement of 75% bisphenol A content with cardanol in the benzoxazine resulted in a copolymer which showed a better or comparable adhesive strength. The adhesion was found to improve further with the incorporation of alumina nanoparticles. The lower viscosity of cardanol-based benzoxazine allowed both solventless synthesis and application of monomers, which is a way forward toward greener chemistry and low volatile organic compound processing strategies.
Diseño y construcción de un escáner bifocal para la obtención de una nube de puntos a través de filtrado y adquisición de imágenes
Authors: Yánez Cajas Jorge , Musuña Toapanta Juan , Oñate Cadena Luis , Campusano Nieto Bayardo
Published: July 2017

En este artículo se presenta el diseño y la implementación de un escáner bifocal para realizar la reconstrucción de imágenes 3D a partir de imágenes en 2D. El escáner está constituido por una base giratoria bifocal compuesta de 2 cámaras web y un láser, la misma que capturará múltiples imágenes desde diferentes ángulos, para luego ser procesadas y digitalizadas. En una etapa posterior se aplicarán técnicas de visión artificial a fin de eliminar ruido, ajustar el brillo, resaltar bordes, mejorar la imagen en escala de grises y seleccionar la región de interés. El proceso de selección de la región de interés indicará los valores de la posición en las coordenadas en X, Y , Z, siendo esta la nube de puntos que se desea encontrar. Esto permite la reconstrucción de 3D a partir de una imagen 2D a través de visión estereoscópica, ya que su análisis se lo realiza por medio de rebanadas o secciones de las imágenes capturadas.
El Proyecto de Uso Múltiple de Agua Paute-Azogues PUMA
Authors: RODAS CECCA HERNÁN
Published: July 2017

El Desastre de la Josefina, despertó iniciativas, proyectos dormidos, activó creativamente a los pueblos afectados.
Elaboración de Bioplaguicidas
Authors: Jara Fausto
Published: July 2017

Uno de los fines principales de toda Universidad, es sin duda alguna, la investigación académica, y más concretamente nuestra Facultad de Ciencias Pecuarias y Agroindustriales de Uzhupud/Paute, debe motivar y apoyar a los estudiantes y catedráticos en todo lo que se refiere a investigaciones agropecuarias y agroindustriales.
Editorial Advisory Board
Authors: BHAC Journal Building Healthy Academic Communities
Published: July 2017

No abstract available
Knowledge, attitude and practice of bio-medical waste management among private practitioners in Poonamallee taluk, Chennai
Authors: Dutta Ruma , R. Prashanth , Parasuraman Gomathy , Jain Timsi , Raja Dinesh , Dcruze Lawrence
Published: July 2017

Background: Inadequate and inappropriate knowledge regarding disposal of Bio-Medical Waste may have serious health consequences to those who handle it as well as can have a deleterious impact on the environment. The objective of the study was to assess the knowledge, attitude and practices about the various aspects of bio-medical waste (BMW) management among private practitioners of Poonamallee taluk, ChennaiMethods: A community based cross-sectional study was conducted to assess the Knowledge, Attitude and Practices about the various aspects of Bio-Medical Waste (BMW) management among private practitioners of Poonamallee taluk, Chennai. The sample size was calculated as 171. Data was collected using a structured interview schedule among all private practitioners including dentists. Data was entered and analyzed by using IBM SPSS software Version 21. Results: 78.3% private practitioners were found to have adequate knowledge about the biomedical waste management rules. 76% private practitioners had knowledge regarding segregation of waste at source. 56.7% of practitioners segregated the BMW into different categories at source level and disposed in specified color coded containers. Conclusions: The importance of training regarding biomedical waste management needs emphasis; lack of proper and complete knowledge about biomedical waste management impacts practices of appropriate waste disposal.
Doses e parcelamento de niacina no desenvolvimento inicial de meloeiro Cantaloupe
Authors: Vendruscolo Eduardo Pradi , Batista Martins Angélica Pires , Seleguini Alexsander
Published: July 2017

A utilização de vitaminas na produção vegetal tem sido voltada para o suprimento de elementos ou visando ação de bioestimulante. No entanto, informações acerca do uso desses compostos são escassas, o que justifica novos estudos que demonstrem os efeitos sobre os vegetais. Assim, objetivou-se com o presente trabalho determinar a melhor dose e o adequado parcelamento da aplicação de niacina para a melhoria das características biométricas de mudas de meloeiro Cantaloupe. O delineamento experimental foi o de blocos ao acaso, em esquema fatorial 4x2, com quatro repetições. Os tratamentos foram compostos por quatro doses de niacina (0; 25; 50; 75 mg L-1) e dois níveis de parcelamento da dose (a cada 8 dias aplicação da dose total ou parcelada à metade, a cada 4 dias). Trinta e dois dias após a semeadura, foi medido o teor de clorofila, altura, diâmetro do coleto, número de folhas, área foliar média, comprimento de raiz e massa seca de parte aérea e raiz. A aplicação de niacina teve efeito quadrático sobre as variáveis de teor de clorofila, diâmetro do coleto, número de folhas, comprimento e massa seca de raiz. Dessa forma, para as condições em que o estudo foi desenvolvido, a aplicação de niacina via fertirrigação, até a concentração 29,4 mg L-1, melhora o desenvolvimento inicial de meloeiro Cantaloupe, independente dos níveis de parcelamento.
Bandolerismo y orden público en el interior peninsular durante el reinado de Carlos IV
Banditry and public order in the interior of the Iberian Peninsula during the reign of Carlos IV
Authors: Martín Polo Manuel
Published: July 2017

RESUMEN Durante el último cuarto del siglo XVIII, y especialmente desde el comienzo del reinado de Carlos IV, toda la Península experimentó una oleada bandolera de proporciones llamativas e intensidad creciente. Las indagaciones de su presencia e impacto en ambas mesetas no dejan lugar a dudas respecto a tal incidencia, que podemos aquilatar a partir de sus cifras (volumen de asaltos y su comparación con otras regiones, aproximación al número e identificación de los bandoleros, o evolución del número de los ajusticiados), pero también de otros aspectos de tipo cualitativo y organizativo. De otra parte, el análisis de la estructura socioeconómica revela que tal efervescencia no fue casual, y que no se pueden desligar ambos extremos en la explicación del fenómeno. El desafío que supuso en materia de orden público dio alas a la militarización desde la década de 1780, aunque sus resultados no respondieron a las expectativas iniciales.   PALABRAS CLAVE: Carlos IV, seguridad y orden público, bandolerismo, Castilla, militarización   ABSTRACT During the last quarter of the 18th century, and especially from the beginning of the reign of Carlos IV, the whole Peninsula experienced a wave of banditry of notable proportions and increasing intensity. The investigations into its presence and impact on both mesetas leaves no doubt about this and is shown by the volume of assaults and its comparison with other regions, estimation of the number and identity of the bandits and the number of those summarily executed as well as other evidence, both qualitative and organizational. Furthermore, the analysis of the socioeconomic structure reveals that such an upsurge did not occur by chance and that neither extreme can be separated from an understanding of the phenomenon. The challenge to public order it represented led to the militarization of the 1780s, which did not produce the expected results. KEY WORDS: Carlos IV, security and public order, banditry, Castile, militarization
Tiempos de violencia desigual: guerrilleros contra Franco (1939-1952)
Times of unequal violence: guerrilla fighters against Franco (1939-1950)
Authors: Díaz Díaz Benito
Published: July 2017

RESUMEN Tras la victoria del general Franco en la Guerra Civil, la paz no llegó por completo a todos los rincones de la geografía española. La falta de una política de reconciliación nacional, junto al mantenimiento de una intensa actividad represora, hicieron que algunos republicanos se refugiasen en la sierra, sin otro objetivo que el de salvar la vida. Con el tiempo, y en paralelo a la evolución de la Segunda Guerra Mundial, el Partido Comunista de España consiguió dotar de objetivos políticos a estos huidos y crear agrupaciones guerrilleras, lo que contribuyó a agravar la violencia rural. En este artículo, con documentación de archivos militares, de partidos políticos y de las fuerzas de orden público, y mediante el uso de la historia oral, abordamos la permanencia de la violencia en el mundo rural: asesinatos, ejecuciones extrajudiciales, fusilamientos públicos, ley de fugas, robos, secuestros, agresiones sexuales, así como otras formas de excesos y coacciones que fueron algo normal en el medio rural durante la década de los años cuarenta del siglo XX.   PALABRAS CLAVE: violencia, represión franquista, huidos, guerrillero, ejecuciones extrajudiciales   ABSTRACT After the victory of General Franco in the Spanish Civil War, complete peace did not come to all corners of Spain. The lack of a policy of national reconciliation, together with the maintenance of strong repressive activity, led some Republicans to take refuge in the mountains with no other purpose than to save their lives. Over time, and in parallel with the evolution of World War II, the Communist Party of Spain managed to provide these fugitives with political objectives and create guerrilla groups, which contributed to the aggravation of rural violence. In this article, using documentation from military archives, political parties and the security forces, as well as oral history, we address the persistence of violence in rural areas: killings, extrajudicial executions, public executions, ley de fugas, robbery, kidnapping, sexual assault and other forms of excesses and oppression that were normal in rural areas during the 1940s.   KEY WORDS: violence, Francoist repression, escapees, guerrilla fighters, extrajudicial executions
Una sociedad silenciada y una actividad económica estancada. El mundo rural bajo el primer franquismo
Authors: Del Valle Calzado Ángel Ramón
Published: July 2017

Reseña de la obra mencionada.
Trazando los orígenes del comportamiento simbólico a través del registro arqueológico paleolítico
Tracking the origins of symbolic behavior through the Paleolithic archaeological record
Authors: Daura luján Joan , Sanz Borràs Montserrat
Published: July 2017

En los últimos decenios, los restos arqueológicos que nos evidencian el comportamiento simbólico por parte de los grupos humanos han ido retrocediendo en el tiempo, hasta situarse en las primeras sociedades paleolíticas. En el presente artículo, se hace un recorrido por las principales evidencias que nos muestran este comportamiento en los grupos de cazadores-recolectores, con especial hincapié en los neandertales y sus ancestros. El trabajo se centra en particular en las prácticas funerarias, la ornamentación personal así como los primeros instrumentos musicales, que nos demuestran que estas sociedades ya disponían de un comportamiento simbólico altamente desarrollado. Este recorrido nos demuestra, además, que el origen del comportamiento simbólico se halla con anterioridad a los humanos anatómicamente modernos y que por lo tanto no tuvo que ver con unas diferencias de tipos biológicas u osteológicas, sino más bien con unas necesidades, probablemente de tipo social. Este corpus de información nos demuestra también que estas sociedades del pasado no fueron tan diferentes de los grupos cazadores-recolectores actuales o de las poblaciones indígenas del presente.PALABRAS CLAVE: Pleistoceno, Paleolítico, neandertales, adornos, simbolismo.ABSTRACTIn recent decades, the time depth of archaeological remains bearing evidence of the symbolic behavior of human groups has been considerably extended, reaching the first Paleolithic societies. This paper provides an overview of the main evidence pertaining to symbolic behavior among huntergatherer groups, with particular emphasis on Neanderthals and their ancestry. This study specifically focuses on burial practices, personal ornaments and early musical instruments, which show thatthose societies already engaged in highly developed symbolic behavior. The overview further shows that the origins of symbolic behavior predate anatomically modern humans and are therefore not linked to biological differences but rather to certain, probably societal needs. This body of information further shows that such past societies were not so different from present day hunter-gatherer groupsor indigenous populations.KEY WORDS: Pleistocene, Palaeolithic, Neanderthal, ornaments, symbolism.
Vestirse a la moda en la España moderna
Dressing fashionably in Modern Era Spain
Authors: Descalzo Lorenzo Amalia
Published: July 2017

Este artículo analiza el vestido y la moda en la España moderna, ya que ambos adquieren en ese momento una importancia muy significativa. La invención de nuevas prendas femeninas durante el reinado de los Reyes Católicos cambió la silueta de la mujer en toda Europa, y su sentido. El protagonismo del vestido español se acrecentó durante el Imperio, cuando España se convirtió en el centro creador de tendencias más importante de la cultura occidental. Sin embargo, en el siglo XVII, la pérdida de importancia de España en el ámbito político frente a la preponderante Francia relegó su moda a un segundo plano a nivel internacional, al tiempo que llevó a los españoles a adoptar su vestido como elemento de identidad.La llegada de los Borbones marcó la adopción del traje francés. No obstante, en la segunda mitad del siglo XVIII emergió una reacción casticista fomentada por los majos frente a la moda del país vecino imperante en toda Europa.PALABRAS CLAVE: España, moda, vestido, apariencia, siglos XVII-XVIII.ABSTRACTThis article analyses clothing and fashion in Modern Era Spain as both acquired significant importance in those times. The invention of new female garments during the reign of the Catholic King and Queen (Ferdinand and Isabel) changed the female silhouette and its meaning all over Europe. The prominence of Spanish clothing increased during the Imperial period and turned Spain into the most important trend-setting center in Western culture. However, in the 17th century, Spain’s lossof importance on the political scene vis-à-vis the predominance of France overshadowed Spanish fashion at the international level while at the same time making Spaniards adopt their clothes as an element of identity.French clothing was adopted with the arrival of the Bourbons. Nevertheless, in the second half of the 18th century there emerged a purist reaction encouraged by los majos against the fashion of the neighboring country, which was prevalent all over Europe.KEY WORDS: Spain, fashion, dress, appearance, XVII-XVIII centuries.
La violencia política en la historiografía sobre la Transición
Political violence in the historiography on the Transition
Authors: Aparicio Rodríguez Víctor
Published: July 2017

El objetivo de este artículo es hacer un balance de la forma en que los principales estudios historiográficos sobre la transición española han abordado la cuestión de la violencia política en dicho proceso histórico. Se suele explicar la transición española como un proceso modélico, en gran parte por el carácter pacífico del mismo. Sin embargo, determinados estudios inciden en la importancia de la violencia política durante la Transición y el impacto que causó en la vida social y política españolas. Ahondar en las diferencias de interpretación sobre la violencia política en los estudios históricos sobre el tema es lo que tratará de ofrecer el presente escrito.PALABRAS CLAVE: Transición, violencia política, historiografía, terrorismo, democracia.ABSTRACTThe objective of this article is to assess the way that the main historiographical studies on the Spanish Transition have approached the question of political violence throughout this historical process. The Spanish Transition is usually regarded as an exemplary process, mainly because of its peaceful nature. Nevertheless, a series of studies focus their interest on the relevance of political violence during the Transition and its impact on Spanish social and political life. This paper presents an attempt to delve into the various interpretations of political violence in historical studies on thistopic.KEY WORDS: Transition, political violence, historiography, terrorism, democracy.
Vías de comunicación romanas en Castilla-La Mancha (Homenaje a Pierre Sillières)
Authors: Valero Tévar Miguel Ángel
Published: July 2017

Reseña de la obra mencionada.
La Guerra de Sucesión española y la opinión pública hispano-británica
Authors: Oncescu Laura
Published: July 2017

Reseña de la obra mencionada.
Rural workers` health related to the use of pesticides in developing and developed countries
Authors: Coelho Enilce Maria , Coelho Fábio Cunha
Published: July 2017

This review aims to examine the issue rural workers' health and the use of pesticides in its various aspects, especially emphasizing how that is doing in developing and developed countries. We found than the rural workers pesticide contamination problems occur both in developing countries as in developed countries. We concluded than to ensure the rural workers’ health when they use pesticides becomes necessary to increase the training of workers. It is also important to build political agendas and actions in the health of agricultural workers, with implementation of preventive health programs with greater oversight and monitoring on pesticide use.
Standardized Test Results: An Opportunity for English Program Improvement
Authors: Jiménez Maureyra , Rodríguez Caroll , Rey Paba Lourdes
Published: July 2017

This case study explores the relationship between the results obtained by a group of Industrial Engineering students on a national standardized English test and the impact these results had on language program improvement. The instruments used were interviews, document analysis, observations, surveys, and test results analysis. Findings indicate that the program has some weaknesses in terms of number of hours of instruction, methodology, and assessment practices that affect the program content and the students’ expected performance. Recommendations relate to setting up a plan of action to make the program enhance student’s performance in English, bearing in mind that the goal is not the students’ preparation for the test but the development of language skills.
A Provocative Approach for Communication with Low-Proficient Children: Examining How the Interactive Role of Teachers and Children Changes
Authors: Damhuis Resi , Van der Zalm Eefje
Published: July 2017

Low-proficient children need to be engaged in high-quality oral interaction as soon as possible. Educational design research was conducted to discover elements of a provocative approach to enhance language and thought development of these children. These elements are presented and illustrated. Interactions were analysed in order to assess how teachers and children changed their role in the interactions, when teachers applied the approach. Results show that change is indeed possible, but not for everyone, nor to the same extent. Implications for teaching and professional learning initiatives are proposed.
HIV Infection of Macrophages: Implications for Pathogenesis and Cure
Authors: Clayton Kiera Leigh , Garcia Victor , Clements Janice E. , Walker Bruce D.
Published: July 2017

Although CD4+ T cells represent the major reservoir of persistent HIV and SIV infection, accumulating evidence suggests that macrophages also contribute. However, investigations of the role of macrophages are often underrepresented at HIV pathogenesis and cure meetings. This was the impetus for a scientific workshop dedicated to this area of study, held in Cambridge, MA in January 2017. The workshop brought together experts in the fields of HIV/SIV immunology/virology, macrophage biology and immunology, and animal models of HIV/SIV infection to facilitate discussions regarding the role of macrophages as a physiologically relevant viral reservoir, and the implications of macrophage infection for HIV pathogenesis and cure strategies. An emerging consensus that infected macrophages likely persist in the setting of combination antiretroviral therapy, driving persistent inflammation and contributing to the viral reservoir, indicate the importance of addressing macrophages as well as CD4+ T cells with future therapeutic strategies.
The effect of two-temperature on thermoelastic medium with diffusion due to three phase-lag model
Authors: Atwa Sarhan Y. , Ammar M. K. , Ibrahim Eman
Published: July 2017

This paper is concerned on the distribution of a homogeneous isotropic elastic medium with diffusion under the effect of Three-phase-lag model. Normal mode analysis is used to express the exact expressions for temperature, displacements and stresses functions. Comparisons are made in the absence and presence of diffusion with some theories like Three-phase-lag and GNIII.
Total Elbow Arthroplasty
Authors: Welsink Chantal L. , Lambers Kaj T.A. , van Deurzen Derek F.P. , Eygendaal Denise , van den Bekerom Michel P.J.
Published: July 2017

Background:

Most total elbow arthroplasty (TEA) designs aim to replicate anatomy and provide stability in the treatment of the degenerative elbow joint. Given the promising results that have been reported following the use of TEA for the treatment of complex fractures, the indications for this procedure are growing. The objective of the present study was to review the most recent literature on the results of the most commonly performed TEAs.

Methods:

A comprehensive literature search was conducted. All relevant studies were reviewed according to a set of predefined inclusion and exclusion criteria. After the initial assessment, 2 authors extracted data from the included articles. Groups were created on the basis of the design of TEA implant, the type of implant (linked or unlinked), and the indication for treatment. Outcome parameters were survival rate, pain, range of motion, complications, and specific elbow outcome scores.

Results:

Seventy-three articles involving a total of 9,379 TEAs were included. The level of evidence was primarily Level IV. Nineteen specific designs of TEA implants were described, including the Souter-Strathclyde (n = 2,387), Coonrad-Morrey (n = 1,586), Kudo (n = 560), and GSB III (n = 498). The most common indication for TEA was rheumatoid arthritis (70%). The weighted mean survival rate for the linked and unlinked prostheses was 85.5% at 7.8 years and 74% at 12.3 years, respectively. For the Coonrad-Morrey, Souter-Strathclyde, and GSB III, the weighted mean survival rate was 87.2% at 7.2 years, 70.6% at 14.2 years, and 81.7% at 9.5 years, respectively. The range of motion after TEA was good overall, with a mean flexion angle of 129° and a mean extension lag angle of 30°. The complication rates ranged from 11% to 38%, with clinical loosening being the most frequently reported complication (7%).

Conclusions:

The results of TEA are respectable overall. It appears that there are small differences between designs. However, despite the fairly good functional results and elbow scores, the survival and complication rates are still not as favorable as those following arthroplasties in other joints.

Level of Evidence:

TherapeuticLevel IV. See Instructions for Authors for a complete description of levels of evidence.
I uploaded a @Youtube vídeo: ¿Una nueva perspectiva de la televisión educativa?
Authors: Salinas Ibáñez Jesús
Published: July 2017

El presente trabajo se ocupa de los avances que en las TIC se producen día a día respecto a las posibilidades de las redes y la televisión y que pueden tener un mayor impacto sobre el ámbito de la formación. Multimedia, televisión interactiva, video podcast, canales de tv... reflejan el crecimiento de la tecnología multimedia que tiende a modificar nuestros hábitos de trabajo y de ocio. Partiendo de las experiencias de televisión educativa que convencionalmente se han venido desarrollando, se trata de indagar fórmulas posibles que los avances de las TIC ofrecen en este ámbito ya sea como receptores y consumidores, ya como productores.
Students' views of, and motivations for, studying A-level Further Mathematics
Authors: Darlington Ellie , Bowyer Jessica
Published: July 2017

In response to recently-announced reforms to A-level Mathematics and Further Mathematics, a large-scale study was undertaken regarding current undergraduates’ views of those qualifications. Students of Science, Technology, Engineering, Medicine and Mathematics (STEMM) and Social Science degrees who had Further Mathematics were surveyed regarding their experiences of the subject and motivations for studying it. Results were positive, across students of a range of degree disciplines, highlighting the benefits of its study as preparation for mathematically-demanding degrees. Whilst access to studying Further Mathematics is poor in some schools, we suggest that more is done by universities to promote its study as a means of better-preparing students for their future degree courses.
A New Mathematics Input Interface with Flick Operation for Mobile Devices
Authors: Nakamura Yasuyuki , Nakahara Takahiro
Published: July 2017

Developing online test environments for e-learning on mobile devices will be useful for increasing drill practice opportunities. To provide a drill practice environment for calculus using an online mathematics test system, such as STACK, we developed a flickable mathematics input interface that can be easily used on mobile devices such as smartphones and tablets. The interface developed using JavaScript and MathDox is mainly for entering mathematical expressions. When the alphabet or number keys on the interface are touched, various candidates of operation appear around the touched key. Flicking in either the leftward, rightward, upward, or downward direction performs the required operation, depending on the selected key. The number of key taps required for entering mathematical expressions on a mobile device using the proposed mathematics input interface is compared with the number of key taps required in direct input; direct input involves using the built-in keyboard of a device. The number of key taps is considerably reduced when using the new mathematics input interface. Furthermore, our new mathematics input interface is compatible with traditional keyboards. The keyboard is automatically selected based on the types of devices being used.
Experience sharing: Mathematical Contest in Modelling (MCM)
Authors: Xu Aiping , Wang Ji
Published: July 2017

In January 2016, Coventry University’s sigma Mathematics Support Centre (MSC) funded three students for MCM, a multi-day mathematics competition held annually in the USA. This is organised by the Consortium for Mathematics and Its Applications (COMAP) and sponsored by the Mathematical Association of America (MAA), the Society of Industrial and Applied Mathematics (SIAM) and the Institute for Operations Research and the Management Sciences (INFORMS). In this article the team leader and advisor reflect on their experience.
Drogas na adolescência, comprometimento biopsicossocial e o papel do médico em escolas: relato de experiência
Authors: Miranda Rodrigues da Cunha Lara , Dias Menezes Bruna , Baleeiro Dantas Allana , Menali Pereira Caproni Samara , Castro de Lima Ciderleia
Published: July 2017

Introdução: O estudo versa sobre a experiência de acadêmicos de medicina ao ministrarem palestras na integração de conhecimentos adquiridos e sua contribuição social, cujo tema central de abordagem foi “Drogas na Adolescência”. Objetivo: relatar a experiência de estudantes de medicina do terceiro período na condução de palestras para adolescentes em escolas de ensino fundamental e médio, com a abordagem temática “Drogas na adolescência, comprometimento biopsicossocial e o papel do médico em escolas”.  Material e Método: Relato de experiência, elaborado com base nas experiências compartilhadas em palestras ministradas aos adolescentes de ensino fundamental e médio do sul de Minas Gerais. Resultado: A aproximação do universo adolescente possibilita conhecer o quanto eles são suscetíveis ao meio, e como eles enfrentam suas inquietações sobre a temática. Poucos são os que participam integralmente, outra parcela sente-se desafiado ou mesmo violados quando sujeitos a receberem informações que a princípio julga saber tudo. Conclusão: As escolas possuem um papel fundamental na formação dos jovens, acredita-se que se possibilitarem o trabalho conjunto de outros profissionais de áreas afins para auxiliar e discutir os aspectos da drogadição, bem como, seus malefícios poderá ser o caminho para a redução do uso das drogas (lícito-ilícitas), com a orientação informa-se, conscientiza-se e garante a saúde integral dos adolescentes, sem prejuízos na fase adulta e para a sociedade.Descritores: Adolescente; Educação; Medicina Preventiva; Transtornos Relacionados ao Uso de Substâncias.
A comparative treatment of bleaching wastewater by physicochemical processes
Authors: Oke Ninad , Singh Swati , Garg Anurag
Published: July 2017

The bleaching effluent discharged from a pulp and paper mill contains chlorinated organic compounds which are toxic to living matter. Physicochemical treatments such as coagulation and different advanced oxidation processes (AOPs) were employed for combined bleaching effluent generated from the first two stages (i.e. chlorination and alkali extraction) (pH = 3.5, chemical oxygen demand (COD) = 1,920 mg/L, and total organic carbon (TOC) = 663 mg/L). At optimum conditions (pH = 7.5, polyaluminium chloride (PAC) dose = 3.84 g/L and slow mixing time = 25 min), ∼68% removal in UV254 and ∼23% TOC removal was obtained during coagulation. Among various AOPs, UV/Fe2+/TiO2/H2O2 system showed the highest TOC and COD removals (∼78%) after 2 h duration (Fe2+:H2O2 molar ratio = 1:100). After the AOP process, chloride ion concentration and biodegradability of the treated wastewater was increased to 2,762 mg/L and 0.46 from an initial value of 2,131 mg/L and 0.29, respectively. The wastewater and sludge analysis showed oxidation and adsorption as the major mechanisms for organics removal. Upon reuse of the regenerated catalysts, TOC removal was reduced significantly. It was found that three times more sludge per unit TOC removal was generated after coagulation in comparison to that produced after UV/Fe2+/TiO2/H2O2 treatment.
Customer Expectations and its Relationship Towards Public Transport in Klang Valley
Authors: Kamaruddin Rohana , Osman 'Ismah , Che Pei Che Anizaliana
Published: July 2017

This study investigates users' expectations towards the services provided by public transportations and its relationships to customer satisfaction, loyalty and environmental factors. Additionally, it also attempts to determine the most preferred mode of public transport. The data was then analyzed using descriptive statistics and structural equation modeling (SEM). The most preferred mode of public transportation was LRT (35.8%), and monorail (28.1%). More importantly, customers' expectations on PT services were based generally on the account of safety. Findings also indicated positive significant relationships between customer satisfactions, environment and loyalty, as well as a positive significant relationship between environmental concern and loyalty.
Особливий випадок інсулінорезистентності в дівчинки 12 років (синдром Рабсона — Менденхолла)
Authors: Sorokman T.V. , Moldovan P.M. , Makarova O.V.
Published: July 2017

У статті наведені результати огляду літератури стосовно синдрому Рабсона — Менденхолла та описаний клінічний випадок цього синдрому. Причиною інсулінової резистентності при синдромі Рабсона — Менденхолла є мутація гена рецептора до інсуліну (ІNSR). Синдром Рабсона — Менденхолла трапляється в дітей обох статей. Поширеність цього захворювання невідома. Генетичний ризик для потомства високий. Каріотип нормальний. У більшості випадків у пацієнтів присутні додаткові особливості цього синдрому. Симптоми синдрому Рабсона — Менденхолла відрізняються в кожному конкретному випадку, однак його можна запідозрити уже на першому році життя за відставанням у прибавці маси тіла, стигмами розвитку (грубі риси обличчя, аномалії зубів, гіперпігментація), аномально сухою шкірою, гіперглікемією й резистентністю до інсуліну, а також за додатковими ознаками (збільшений живіт, аномальний клітор, часті зригування, кетоацидоз). Діагноз підтверджується генетичними дослідженнями. Описаний клінічний випадок становить безперечний інтерес з погляду поєднання виразки дванадцятиперстної кишки, цукрового діабету, що мав лабільний перебіг і проявлявся частими епізодами кетоацидозу, та особливостей мутації ІNSR.
Рівень глікемії та інсулінорезистентності у хворих на цукровий діабет 2-го типу, діабетичну ретинопатію та ожиріння
Authors: Malachkova N.V. , Komarovskaya I.V. , Kyryliuk M.L.
Published: July 2017

Актуальність. Діабетична ретинопатія (ДР) є провідною причиною втрати зору у всьому світі. Мета дослідження: вивчити рівень глікемії та інсулінорезистентності у хворих на ДР на тлі цукрового діабету 2-го типу (СД2) і ожиріння. Матеріали та методи. Дослідження проведені в 137 пацієнтів (234 ока), розподілених на дві групи. Результати. Подано результати дослідження за допомогою двофакторного дисперсійного аналізу ступеня інсулінорезистентності як головного кластера метаболічного синдрому на різних стадіях ДР, а також показників вуглеводного обміну як одного з провідних чинників ризику прогресування ретинопатії при СД2 з урахуванням обтяжливих факторів перебігу СД2 (вік хворих, тривалість діабету, ступінь його компенсації) і виду цукрознижувальної терапії. Показано, що всі пацієнти з ДР, незалежно від досліджуваної групи, перебувають у стані хронічної гіперглікемії при декомпенсації СД2. Висновки. Показники вуглеводного обміну розпочинають поліпшуватися тільки в проліферативній стадії ДР, однак це трапляється на тлі тяжких гіпоглікемій. У проліферативній стадії ДР перебуває найбільша кількість хворих із несприятливими індексами інсулінорезистентності за індексом HOMA-IR і зниженою чутливістю до інсуліну за індексом QUICKI.
Fringe Banking in Canada: The Collective Economies of Toronto’s “Banker Ladies”
Authors: Hossein Caroline Shenaz
Published: July 2017

Rotating savings and credit associations (ROSCAs) are regarded as a time-honoured tradition practiced by many people around the world. African Canadians value ROSCAs because of how they have helped people adjust to Canadian life. This study examines ROSCAs and the role that African Canadians have played in Canada’s social economy. It includes interviews with 77 people, 46 of whom are “Banker Ladies”—African Canadian women who create community-driven financial cooperatives in Canada’s largest financial centre, Toronto. ROSCAs have been incubating within the Canadian diaspora for the past 70 years as a way to counteract the business exclusion. For the social economy in Canada to be reflective of society, the research and theories that drive the sector must reflect a cultural awareness of the various cooperative forms led by racialized Canadians.Plusieurs personnes dans le monde suivent la tradition vénérable des associations rotatives d’épargne et de crédit (AREC). Les Afro-Canadiens valorisent les AREC pour la manière dont celles-ci ont aidé les gens à s’adapter à la vie canadienne. Cette étude examine les AREC et le rôle joué par les Afro-Canadiens dans l’économie sociale du pays. Elle inclut des entretiens avec 77 personnes, y compris 46 femmes banquières—des Afro-Canadiennes créant des coopératives financières communautaires dans le plus grand centre financier du Canada, Toronto. Depuis 70 ans, les AREC persistent au sein de la diaspora canadienne afin de contrer les défaillances du système bancaire classique. Pour que l’économie sociale au Canada puisse refléter la société telle qu’elle est, la recherche et la théorie relatives au secteur doivent tenir compte des divers formats de coopératives menées par des Canadiens et Canadiennes racialisés.
EDITORIAL
Authors: Abadía García Constanza
Published: July 2017

La gestión del conocimiento aplicada a la universidad se erige como un nuevo paradigma que permite identificar y orientar los recursos científicos y tecnológicos-capital humano y estructural-, de manera sistemática, a fin de alcanzar los objetivos trazados por una institución. De esta forma, se constituye en el elemento crítico que permite a las instituciones de educación superior potenciar y acelerar la velocidad con que manejan los nuevos retos y oportunidades, lo que se logra apalancando lo más valioso de sus recursos: el conocimiento, el talento, la creatividad y, en general, los intangibles de la organización.
La utilización de mapas conceptuales y mentales en el aprendizaje significativo
Authors: Soto Carrión Carolina , Chata Mamani Haydée , Jiménez Mendoza Wilber
Published: July 2017

El presente trabajo es una investigación de tipo aplicada, de nivel experimental y de diseño cuasi-experimental.

La selección de la muestra fue no probabilística, el tipo de muestreo fue intencional, distribuidos en dos grupos, uno de control y otro experimental, a quienes se les aplicó la lista de cotejo y la prueba objetiva de conocimientos pre-test, pos-test. Se determinó que la aplicación de la técnica de mapas conceptuales y mentales influyó
elevando el nivel de aprendizaje significativo.
Nuevas comprensiones interdisciplinares de las emociones a la luz del siglo XXI
Authors: Lasso Cárdenas Edilberto
Published: July 2017

Filósofos, psicólogos, neurólogos y biólogos recientemente se han ocupado de desentrañar el estudio de las emociones. Aunque están sentados en orillas distintas, todos, sin excepción, critican severamente la posición de quienes, afincados en una concepción tradicional, siguen viendo a las emociones como fuerzas ciegas que perturban a la razón. Estos autores, por el contrario, indagan a partir de sus investigaciones la vinculación del componente cognitivo en el emocional.

Darwin, Pinker e incluso Budistas han planteado un conjunto determinado de emociones básicas que subyacen a todas las culturas de la humanidad.

Sin duda que el manejo adecuado de las emociones no puede estar alejado de unas disposiciones interiores que la persona debe cultivar, pues marcarán la pauta para tomar decisiones u opciones sensatas. El arte, de modo particular, induce, en la persona emociones. Éstas son fuente de catarsis; otras tienen un componente, social o cognitivo.
Análisis del contexto e-learning en la UNAD. Una mirada desde los entes tecnológico, social y pedagógico
Authors: Bilbao Clara Esperanza , Velásquez Lorena Marcela , Martínez Diana Liceth , Fernández Alexander
Published: July 2017

El presente análisis establece el estado actual del modelo e-learning a partir de los entes tecnológico, social y pedagógico en la Universidad Nacional Abierta y a Distancia (UNAD). El planteamiento del análisis se da a partir de los resultados de una exploración a las posturas conceptuales desde estudios empírico-analíticos, fenomenológicos y sistémicos a nivel global, que brindan los argumentos para dar una mirada a la institución desde la articulación tecnológica, social y pedagógica. El documento presenta la visión integral del e-learning a manera de introducción, establece los entes necesarios y posteriormente enlaza los mismos al contexto Unadista resaltando su articulación.

Los resultados reflejan posturas sobre el estado actual del contexto
e-learning institucional.