bluuebunny/crossref_metadata_2025 huggingface dataset:
Citizen Science and Multimedia Didactic Resources: Knowledge of Mosquito-Borne Diseases in an Urban Area of Southwestern Colombia
Authors: Bedoya-Rodríguez Francisco Javier , Guevara-Fletcher Carlos Eduardo , Pelegrin Jonathan S.
Published: October 2024

Citizen science resources have had great relevance in community educational intervention, fostering interest in ecological research projects. This study investigated the influence of the application of multimedia didactic resources focused on citizen science and analysis of sociodemographic variables to improve the levels of ecological knowledge about mosquito-borne diseases. For this, a probabilistic sample of 172 participants from an urban sector in southwestern Colombia was selected. A multimedia didactic material was designed for the educational intervention and evaluated by means of pretest and posttest. To assess whether the educational intervention was statistically significant, the data were processed with statistical inference to determine the influence of various variables (gender, age, marital status, schooling, and occupation) on each person’s ecological knowledge. The findings showed a significant increase in the knowledge levels of the participants. The marital status variable (married and cohabiting) significantly influenced ecological knowledge. These participants are more likely to obtain high knowledge, associated with the prevention of their family environment. This study demonstrated that multimedia didactic strategies are an important factor to take into account in the structuring of environmental education and citizen science projects. For future research, it is suggested to deepen the relationship between sociodemographic variables and ecological knowledge.
SMC5/6-Mediated Transcriptional Regulation of Hepatitis B Virus and Its Therapeutic Potential
Authors: Bächer Johannes , Allweiss Lena , Dandri Maura
Published: October 2024

Cells have developed various mechanisms to counteract viral infections. In an evolutionary arms race, cells mobilize cellular restriction factors to fight off viruses, targeted by viral factors to facilitate their own replication. The hepatitis B virus (HBV) is a small dsDNA virus that causes acute and chronic infections of the liver. Its genome persists in the nuclei of infected hepatocytes as a covalently closed circular DNA (cccDNA) minichromosome, thus building up an episomal persistence reservoir. The chromosomal maintenance complex SMC5/6 acts as a restriction factor hindering cccDNA transcription, whereas the viral regulatory protein HBx targets SMC5/6 for proteasomal degradation, thus relieving transcriptional suppression of the HBV minichromosome. To date, no curative therapies are available for chronic HBV carriers. Knowledge of the factors regulating the cccDNA and the development of therapies involving silencing the minichromosome or specifically interfering with the HBx-SMC5/6 axis holds promise in achieving sustained viral control. Here, we summarize the current knowledge of the mechanism of SMC5/6-mediated HBV restriction. We also give an overview of SMC5/6 cellular functions and how this compares to the restriction of other DNA viruses. We further discuss the therapeutic potential of available and investigational drugs interfering with the HBx-SMC5/6 axis.
Insect–Virus Interactions: A Fascinating Area of Research That Requires Ongoing Attention
Authors: Pan Li-Long
Published: October 2024

As the most abundant and diverse groups of animals, insects play many important roles in the ecosystem, such as those of herbivores, vectors, and pollinators [...]
Differential Adjuvant Activity by Flagellins from Escherichia coli, Salmonella enterica Serotype Typhimurium, and Pseudomonas aeruginosa
Authors: Pang Shengmei , Liu Mei , Wang Longlong , Shao Mingqing , Zhu Guoqiang , Duan Qiangde
Published: October 2024

(1) Background: The adjuvant properties of flagellin from various bacterial species have been extensively studied; however, a systematic comparison of the immunoadjuvant effects of flagellins from different bacterial species is lacking. This study aims to analyze the amino acid sequences and structural features of flagellins from Escherichia coli (FliCE.C), Salmonella enterica serotype Typhimurium (FliCS.T), and Pseudomonas aeruginosa (FliCP.A), and to evaluate their adjuvant activities in terms of Toll-like receptor 5 (TLR5) activation, antibody production, and cytokine responses in a murine model. (2) Methods: Bioinformatics analysis was conducted to compare the amino acid sequences and structural domains (D0, D1, D2, and D3) of flagellins from the three bacterial species. PyMol atomic models were used to confirm structural differences. Toll-like receptor 5 (TLR5) activation assays were performed to measure IL-8 and TNF-α production in vitro. The IgG antibody titers against the model antigen FaeG and cytokine responses, including IL-4 and TNF-α secretion were evaluated in a murine model. (3) Results: Bioinformatics analysis revealed that the D0 and D1 domains are highly conserved, whereas the D2 and D3 domains exhibit significant variability across the three species. Structural analysis via PyMol confirmed these differences, particularly in the D2 and D3 domains. TLR5 activation assays showed that FliCS.T and FliCP.A induced higher levels of IL-8 and TNF-α production compared to FliCE.C, indicating species-specific variations in TLR5 activation. In the murine model, FliCS.T as an adjuvant produced higher antibody titers against FaeG and increased IL-4 secretion in splenocytes compared to FliCE.C and FliCP.A. FliCP.A induced higher TNF-α expression than FliCS.T and FliCE.C, suggesting FliCS.T and FliCP.A are more effective at inducing T-cell responses. (4) Conclusions: This study highlights the potential of FliCS.T and FliCP.A as potent vaccine adjuvants. The results provide insights into the structure–function relationships of these flagellins and support their application in enhancing immune responses against diverse pathogens.
B and T Cell Bi-Cistronic Multiepitopic Vaccine Induces Broad Immunogenicity and Provides Protection Against SARS-CoV-2
Authors: Perdiguero Beatriz , Álvarez Enrique , Marcos-Villar Laura , Sin Laura , López-Bravo María , Valverde José Ramón , Sorzano Carlos Óscar S. , Falqui Michela , Coloma Rocío , Esteban Mariano , Guerra Susana , Gómez Carmen Elena
Published: October 2024

Background: The COVID-19 pandemic, caused by SARS-CoV-2, has highlighted the need for vaccines targeting both neutralizing antibodies (NAbs) and long-lasting cross-reactive T cells covering multiple viral proteins to provide broad and durable protection against emerging variants. Methods: To address this, here we developed two vaccine candidates, namely (i) DNA-CoV2-TMEP, expressing the multiepitopic CoV2-TMEP protein containing immunodominant and conserved T cell regions from SARS-CoV-2 structural proteins, and (ii) MVA-CoV2-B2AT, encoding a bi-cistronic multiepitopic construct that combines conserved B and T cell overlapping regions from SARS-CoV-2 structural proteins. Results: Both candidates were assessed in vitro and in vivo demonstrating their ability to induce robust immune responses. In C57BL/6 mice, DNA-CoV2-TMEP enhanced the recruitment of innate immune cells and stimulated SARS-CoV-2-specific polyfunctional T cells targeting multiple viral proteins. MVA-CoV2-B2AT elicited NAbs against various SARS-CoV-2 variants of concern (VoCs) and reduced viral replication and viral yields against the Beta variant in susceptible K18-hACE2 mice. The combination of MVA-CoV2-B2AT with a mutated ISG15 form as an adjuvant further increased the magnitude, breadth and polyfunctional profile of the response. Conclusion: These findings underscore the potential of these multiepitopic proteins when expressed from DNA or MVA vectors to provide protection against SARS-CoV-2 and its variants, supporting their further development as next-generation COVID-19 vaccines.
Evaluation of the Use of Sub-Immunodominant Antigens of Babesia bovis with Flagellin C Adjuvant in Subunit Vaccine Development
Authors: Rojas Manuel J. , Bastos Reginaldo G. , Navas Jinna A. , Alzan Heba F. , Laughery Jacob M. , Lacy Paul A. , Ueti Massaro W. , Suarez Carlos E.
Published: October 2024

Bovine babesiosis caused by the tick-borne apicomplexan parasite Babesia bovis remains a threat for cattle worldwide, and new vaccines are needed. We propose using immune-subdominant (ISD) antigens as alternative vaccine candidates. We first determined that RAP-1 NT and RRA are subdominant antigens using recombinant antigens in ELISAs against sera from B. bovis-protected cattle. Protected animals demonstrated high antibody responses against the known immunodominant rRAP-1 CT antigen, but significantly lower levels against the rRAP-1 NT and rRRA antigens. Next, a group of cattle (n = 6) was vaccinated with rRRA and rRAP-1 NT using a FliC–Emulsigen mix as the adjuvant, and there was a control group (n = 6) with the adjuvant mix alone. All but one immunized animal demonstrated elicitation of strong humoral immune responses against the two ISD antigens. Acute babesiosis occurred in both groups of cattle upon a challenge with the virulent B. bovis, but a significant delay in the average rate of decrease in hematocrit in the vaccinated group, and an early monocyte response, was found in half of the vaccinated animals. In conclusion, we confirmed the immune subdominance of rRRA and rRAP-1 NT and the ability of FliC to increase immunogenicity of ISD antigens and generate useful information toward developing future subunit vaccines against B. bovis.
Characteristics and Correlation Study of Mountainous Lake Ice Phenology Changes in Xinjiang, China Based on Passive Microwave Remote Sensing Data
Authors: Kuluwan Yimuran , Rusuli Yusufujiang
Published: October 2024

Lake ice phenology directly reflects local climate changes, serving as a key indicator of climate change. In today’s rapidly evolving climate, utilizing advanced remote sensing techniques to quickly extract long-term lake ice phenology features and studying their correlation with other climate factors is crucial. This study focuses on lakes in Xinjiang, China, with a mountainous area greater than 100 km2, including Sayram Lake, Ayahkum Lake, Achihkul Lake, Jingyu Lake, and Ahsaykan Lake. The Bayesian ensemble change detection algorithm was employed to extract lake ice phenology information, and the Mann–Kendall (MK) non-parametric test was used to analyze trends. The visual interpretation method was used to interpret the spatial evolution characteristics of lake ice, and the Pearson correlation coefficient was used to explore the driving factors of lake ice phenology. Results indicate the following: (1) Jingyu Lake exhibited the most significant delay in both freezing and complete freezing days, while Ayahkum Lake showed the most stable pattern. Ahsaykan Lake demonstrated the least delay in both starting and complete melting days. (2) Sayram Lake’s ice evolution was unstable, with wind causing variability in the locations where freezing begins and melting spreading from the west shore. Ayahkum Lake, Ahsaykan Lake, and Jingyu Lake exhibited similar seasonal variations, while Achihkul Lake’s ice spatial changes spread from the east to the center during freezing and from the center to the shore during melting. (3) The study found that the freeze–thaw process is influenced by a combination of factors including lake area, precipitation, wind speed, and temperature.
Enhanced Assessment of Water Quality and Pollutant Source Apportionment Using APCS-MLR and PMF Models in the Upper Reaches of the Tarim River
Authors: Zhang Shengnan , Wang Shan , Li Fayong , Liu Songjiang , You Yongjun , Liu Chong
Published: October 2024

To evaluate the pollution sources and dynamics of the upper reaches of the Tarim River, 10 typical sampling points were selected, and 23 water quality parameters from 2020 to 2022 were analyzed using one-way analysis of variance, the comprehensive Water Quality Identification Index (WQI), and Principal Component Analysis (PCA). The pollution status, sources, and contribution rates of water quality were investigated using the Absolute Principal Component-Multiple Linear Regression Model (APCS-MLR) and Positive Matrix Factorization (PMF). The results indicated that the water quality parameters of dissolved oxygen (DO), chemical oxygen demand (CODMn), biochemical oxygen demand after 5 days (BOD5), total nitrogen (TN), total phosphorus (TP), fluoride ions (F−), and ammonia-nitrogen (NH3-N) in the upper reaches of the Tarim River exceed standards, with noticeable spatial variations observed for each parameter. The water quality evaluation grades in the upper reaches of Tarim River primarily indicate “moderate” and “good” levels, with DO, TN, NH3-N, and electrical conductivity (EC) being the key parameters influencing variations in water quality. The source analysis results from APCS-MLR and PMF yielded similar outcomes, identifying six potential pollution sources. Among these, soil weathering, livestock and poultry breeding, and agricultural activities exhibited higher contribution rates. Specifically, the contribution rates for these sources according to APCS-MLR were 44.11%, 19.63%, and 11.67%, respectively; while according to PMF they are 24.08%, 17.88%, and 27.54%, respectively. Furthermore, industrial pollution sources contributed at a rate of 6.01% according to APCS-MLR, while urban living sources contributed at a rate of 2.13%. However, based on PMF analysis, the contribution rates for industrial pollution sources increased significantly to 16.71%. Additionally, APCS-MLR identified natural sources as contributing at a rate of 16.45%, whereas PMF suggested that a combination of agricultural activities and natural sources contributed at a lower rate of only 9.52%. In conclusion, the water quality within the upper reaches of the Tarim River is predominantly satisfactory. Nonetheless, localized pollution, primarily attributable to human activities, presents a substantial challenge. These observations provide critical insights into improving and protecting the fragile water quality of the Tarim River.
Can eDNA Present in Aquatic Environments of Rural Areas Help Identify Species Diversity in the Order Anura?
Authors: Kim Keonhee , Kwon Sera , Jang Yikweon
Published: October 2024

Paddy fields are classified as wetland environments, and they comprise freshwater ecosystems. They are ecologically important habitats and breeding grounds for many aquatic insects, amphibians, and reptiles. However, paddy field ecosystems are constantly threatened by climate change and the indiscriminate use of pesticides. The metabarcode analysis of eDNA (environmental DNA) method is highly effective at accumulating information on many organisms that inhabit paddy field ecosystems. It can indirectly identify the existence of taxa that are no longer found in the target ecosystem due to behavioral characteristics, such as those exhibited by amphibians. In the metabarcoding results of this study, genes of five species of frogs were found, but it was impossible to confirm all of the frogs’ taxa, morphological pictures, and croak sounds. On the other hand, some frog taxa were only found in the metabarcoding analysis. The eDNA of the frogs found only in the metabarcoding analysis is estimated to have been introduced from nearby areas inhabited by frogs rather than the target region. Due to the powerful analytical resolution of eDNA metabarcoding, this eDNA-based paddy field search is expected to help investigate the biodiversity in agricultural ecosystems.
A Review on Role of Macro - Nutrients in Sports Personalities
Authors: Jannathul Roshan Sabiha S , Vadivel Devi M , Rama Jeba S
Published: October 2024

Because of the increased needs for energy and nutrients in sports, there is a strong correlation between nutrition and health. Understanding the metabolism of the activity is essential to understanding the various metabolic processes that coexist during sports practice. For optimal performance during all forms of activity, nutrition is crucial. The foods an athlete eats are used to feed their body with the right minerals and energy to maximize their performance during physical exercise. Athletes’ competition and training regimens must include fact sport nutrition guidelines that examine the relationship between health, fitness, and nutrition. To guarantee that athletes exercise more efficiently to lower the risk of harm and illness, guidelines for the quantity, structure, and time of food intake must be founded on solid scientific evidence. Blood glucose and muscle glycogen are the main energy sources used by contracting muscles. Protein may be necessary for athletes not only to reduce the danger of deficiency that comes with following dietary recommendations, but also to support higher functioning and maybe adaption to the workout stimulus. Sufficient consumption of fat is crucial for maintaining energy balance, promoting optimal health, maximizing the absorption of fat-soluble vitamins and vital fatty acids, and restoring intramuscular triacylglycerol reserves. It’s crucial to consume adequate water daily, particularly if you participate in sports and may demand electrolytes. Athletes are advised to take fluids and electrolytes, like sodium, for many purposes, including pre-, during, and post-exercise. This review analyzes the dietary requirements of athletes.
A Study on Nutrient Evaluation of Sesbenia Grandiflora Flower Powder Incorporated in Soup Varieties
Authors: Veeralakshmi S
Published: October 2024

The agathi is a fast -growing tree The plant (botanical name Sesbania grandiflora) the flower white, pink and red. Sesbenia grandiflora, commonly called as vegetable hummingbird, katurai, agathi.The flowers hang in bell-like clusters behind the thicket of leaves. the flowers rank high in nutritional and medicinal value. The flowers growing most in February-March. . the flower rich in calcium, phosphorus, fat, iron,vitamins A, B, and C. Sesbania grandiflora plant is important medicinal plant .the flower cure in heart palpitation, inflammation, kidney related diseases including cancer. The Sesbenia grand flora highly nutrient rich in vitamins and minerals. The leaves of Sesbania grandiflora flower have been used in local traditional medicine.
Impact of Digital Advertising on Brand Visibility in B2B at Petrocoat Speciality Chemical Private Limited
Authors: Ponkavi E , Saraswathy C
Published: October 2024

In the digital era, business-to-business (B2B) businesses’ visibility is greatly influenced by digital advertising. Through a review of previous research, empirical studies, and industry data, this study investigates the ways in which digital advertising methods affect the visibility of brands within the B2B sector. It examines several digital advertising platforms and strategic factors to make campaigns successful. This research seeks to assist B2B marketers in leveraging digital advertising to improve their brand’s visibility and achieve a competitive edge by providing useful insights and advice.
Development and Standardization of Germinated and Fermented Foxtail Millet Flour Incorporated Idli Batter for Enhancing Sports Performance
Authors: Vijayarani D , Lailath Nisha S
Published: October 2024

Millets are a group of cereal grains that belong to the Poaceae family, commonly known as grass family. They contain many health promoting nutrients. Among the millets, Foxtail Millet (Seteria italica) is a highly nutritive, gluten free, easy to digest and non-acid forming millet. Fermentation improves gut health which is an essential part of athletic performance. It improves digestion, enhances absorption of nutrients, strengthens the immune system and improves intense exercise tolerance.In this study, Foxtail millet was soaked for 24 hours and germinated for 96 hours due to high antioxidant of 94% and less antinutritional factors. The germinated millet was subjected to cabinet drying and powdered. Foxtail millet Idly was prepared in various proportionsat 10 hours fermentation. The fermented product was subjected to sensory evaluation and the result revealed that 50%foxtail milletflour incorporated idliwas highly ranked based on the overall acceptability. Foxtail millet flour incorporated idly batter was prepared with the selected proportion of 3:1 ratio in different fermentation intervals of 6 hours,8 hours,10 hours and 12 hours. The comparative analysis of protein and vitamin C showed that when the fermentation period of idli batter increased, protein and vitamin C contents were also increased. Protein plays an important role in building and maintenance of muscles. High protein intake prevents soreness ,improves endurance, musclerepair, recovery and reduces muscle damage. Antioxidants like vitamin C is beneficial in assisting with sports recovery and supporting return from injury. Hence, the germination and fermentation processesfor millets could be utilized to prepare low cost nutritious food products, to enhance sports performance and to improve the nutritional status of the athletes.
Threat Posed by Artificial Intelligence to Humanity in Future
Authors: Sai Naaresh S , Aadityan Krishanu G
Published: October 2024

Artificial Intelligence (AI) emerges as a transformative force set to reshape industries and societies, yet it also presents significant threats to humanity. This study explores the multifaceted risks associated with AI, analyzing ethical, economic, and governance dimensions. Ethical concerns arise from algorithmic bias, privacy breaches, and the potential misuse of autonomous weapons. Economically, AI-driven automation poses a threat of widespread job displacement, demanding proactive measures to address societal inequality. Additionally, AI’s security vulnerabilities jeopardize cyber security and national safety, necessitating robust protective measures. Moreover, the prospect of AI surpassing human intelligence raises existential questions, prompting the exploration of strategies for its safe development. Tackling these challenges requires coordinated international efforts, including regulatory reforms and ethical frameworks. By examining AI threats comprehensively, this research aims to guide policymakers, technologists, and society toward responsible AI deployment for humanity’s well-being in the AI-driven era.
Impact of Influencer Marketing on Consumer Purchasing Behavior
Authors: Prasanth MN , Shanmuga Priyan S
Published: October 2024

The digital age has witnessed a monumental shift in marketing strategies, with influencer marketing emerging as a dominant force in shaping consumer purchasing behavior. This article meticulously dissects the intricate web of factors that empower social media personalities to exert such a persuasive influence over consumer choices. Through a comprehensive analysis of current trends and research findings, the article sheds light on the psychological underpinnings that drive consumer trust in influencer recommendations. Two key concepts emerge: social proof and trust. Consumers exhibit a heightened inclination towards products endorsed by individuals they perceive as relatable and credible. Influencers who cultivate genuine connections with their audience foster a sense of social validation. This leads followers to believe that using the promoted product grants them access to a coveted lifestyle or social circle, mirroring the choices of the influencer they admire. Furthermore, the article explores the concept of perceived expertise. Extensive research suggests that consumers often view influencers as possessing a wealth of knowledge about the products they advocate for, attributing a significant degree of credibility to their endorsements. This perception is particularly strong in niche communities where influencers have meticulously built their image as thought leaders within a specific domain. The article acknowledges the inherent limitations and ethical considerations that cloud the realm of influencer marketing. Lack of transparency and the potential for inauthenticity pose significant challenges.
Impact of Technological Advancements in the Decisions of Human Resource Department
Authors: U Sethuraman , MJ Yeshwanth
Published: October 2024

This research paper delves into the intricate relationship between Artificial Intelligence (AI), Machine Learning (ML), and decision-making processes in Human Resources (HR) within modern organizational settings. As technology continues to evolve, HR practices are undergoing significant transformations due to the influence of AI and ML. The study examines the various ways these technologies are applied across crucial HR areas such as recruitment, talent management, performance evaluations, and employee engagement. Through an analysis of the benefits, obstacles, and ethical considerations associated with incorporating AI and ML into HR practices, the research aims to provide a comprehensive understanding of their impact on organizational dynamics. Additionally, the exploration of how these technologies affect diversity and inclusion initiatives within the workforce adds a nuanced perspective to the inquiry. The findings of this research offer valuable insights for HR professionals, policymakers, and organizational leaders navigating the evolving landscape where human judgment intersects with artificial intelligence.
Navigating Choices: A Study on Consumer Perception on Brands and their Marketing During Indian Premier League (IPL)
Authors: Anaikomagan Kethampatti Kesavan
Published: October 2024

This particular research deeps dive into understanding of how brands and their marketing make a huge impact in particular in such a way that improves their brand value when it comes to sponsorship and other advertising placements during the Indian Premier League (BCCI’s flagship cricket mega event) This study further tries to understand the relationship between the product placements of brands that have been associated with either IPL teams (Or) have been official partners for the mega event. Enhancing the amount of sale projections and ROI related to the brands will also be equally discussed as it is of the most important parameter to be understood. IPL happens once in every year which is during the March-May window of ICC’s FTP (Future Tour Programme) and it is during this time there is peak rush for tickets at various stadiums and restaurants with huge screening facilities, the brands get associated there too. Some of the brands have been having long term association and some have just made inroads that is well thought of understanding the market dynamics.
Role of Artificial Intelligence (Ai) and Machine Learning (Ml) in Financial Decision-Making
Authors: V Jayavarshni
Published: October 2024

In the banking business, the use of artificial intelligence (AI) algorithms to detect fraud, automate trading activities, manage portfolios, and provide customer service has increased significantly in recent years. Artificial intelligence (AI) uses statistical modeling to create predictions. Managing relationships and providing investors with financial advisory services. The inherent capacity of AI to quickly analyze several data sets and create different business scenarios to aid in decision-making can enhance an organization’s financial performance without explicitly programming for predicted results. This study examines how well AI is implemented in the Indian financial sector, as well as how much progress has been made in this area Integration has produced. The study addresses some of the contemporary AI technologies used in the Indian financial sector and attempts to investigate the comfort level and expectations of these workers with regard to AI use. Additionally, it attempts to statistically examine the degree of integration and potential relationship between AI systems and the features and efficacy that they have brought to financial decision making across all industries and participants in the Indian financial sector, as well as across all job levels within various financial organizations.
The Role of Artificial Intelligence (AI) and Machine Learning (ML) in HR Decision Making Processes
Authors: VC Keshavi
Published: October 2024

This research paper delves into the dynamic interplay between artificial intelligence (AI), machine learning (ML), and human resources (HR) decision-making processes within contemporary organizational landscapes. As technological advancements continue to reshape the workplace, HR practices are not immune to the transformative influence of AI and ML. The study explores the multifaceted applications of these technologies in key HR domains, including recruitment, talent management, performance evaluations, and employee engagement. By scrutinizing the advantages, challenges, and ethical considerations associated with the integration of AI and ML in HR, the research aims to provide a comprehensive understanding of their impact on organizational dynamics. Moreover, an exploration of how these technologies influence diversity and inclusion initiatives within the workforce adds a nuanced dimension to the investigation. The findings of this research contribute valuable insights for HR professionals, policymakers, and organizational leaders navigating the evolving landscape where human judgment intersects with artificial intelligence.
A Study on Challenges and Benefits of Remote and Hybrid Work Model from Employees Perspective
Authors: Rathi Yash
Published: October 2024

This research study delves into the multifaceted landscape of remote and hybrid work models, focusing specifically on the experiences and perspectives of employees. As the global workforce undergoes a profound transformation, understanding the challenges and benefits associated with remote and hybrid work arrangements becomes imperative for organizations striving to adapt to the evolving work environment. Through qualitative and quantitative analysis, this study aims to provide insights into the key factors shaping employees’ experiences, including the impact on work-life balance, productivity, communication, collaboration, and overall job satisfaction. By synthesizing empirical data and existing literature, this research contributes to a deeper understanding of the complexities inherent in remote and hybrid work models, offering valuable implications for both employers and employees navigating this paradigm shift. The hybrid workplace is a concept on the lips of every industry trend in the world today. With digitalization becoming more normalized across every sphere in the global village. Every workplace needs to maximize and transcend obstacles and innovations to ease into the hybrid workplace. The work from home also becomes more relevant during the pandemic. The study was conduct in Kannura corporate IT company. This research paper focused on understanding the impact of both hybrid and work from home and the various challenges and benefits and also the preference of the employees to the future work model. The study was carried out by primary data with a sample size of 120 employers which were chosen by simple random sampling method. To analyse benefits of Work from home and hybrid work model, to analyse challenges of Work from and hybrid work model, to analyse the preference of employees in choosing the future work model. Statistical tools used for this data collection are simple frequency analysis, Independent sample T- test, Chi square test, One-way Anova: The finding soft the study revealed that the employees are happy with choosing hybrid work model as their future model. The employees can work as per their comfort zone and their comfort place to work.
A Study on Consumer Perception towards Perfumes
Authors: CN Harshitha
Published: October 2024

Perfumes have become an integral part of daily grooming, offering individuals a sense of luxury and sophistication. Understanding consumer perception towards perfume is crucial for perfume manufacturers and marketers to develop effective strategies for product positioning and successful brand management. This research aims to explore the various factors that influence consumer perception of perfume, including fragrance composition, packaging, brand image, and social influence. The research will employ a mixed-methods approach, combining qualitative and quantitative techniques. Qualitative methods such as in-depth interviews and focus groups will be conducted to gain insights into consumers’ emotional associations with different fragrance compositions. Participants will be asked to describe their preferences and the emotions evoked by various scent categories, including floral, woody, citrus, and oriental fragrances. These interviews will provide valuable insights into the subjective perceptions and expectations consumers have towards perfume scents. Additionally, the research will utilize quantitative methods to examine the impact of packaging and brand image on consumer perception. A survey will be administered to a diverse sample of perfume consumers, assessing their preferences for different packaging designs, colors, and materials. The survey will also investigate the influence of brand reputation and associations on consumers’ perception of perfume quality and desirability. Furthermore, the research will explore the role of social influence on consumer perception. Social media platforms will be analyzed to identify trends and consumer discussions related to perfumes. The research will examine the influence of online reviews, recommendations from friends and family, and the role of influencers in shaping consumer perception towards perfume. The findings of this research will provide valuable insights for perfume manufacturers and marketers to understand consumer preferences and develop effective marketing strategies.
A Study on Analysing CMRL Tickets System
Authors: Santhosh S.P.
Published: October 2024

An important part of our daily lives is transportation. The purpose of this article is to create an online payment transaction process in place of a manual one. By using e-ticketing, we can lessen the burden that comes with carrying tickets for travellers. Metro cards cut down on the amount of time needed for manual ticket creation, but commuters need to make sure they have their card with them at all times. The commuters can control reservation and cancelation with our system.
A Study on Tourism and Level of Satisfaction of Tourists
Authors: Stepheno Ancy , P Raghul
Published: October 2024

The project titled ‘A study on tourism services and level of satisfaction of tourists,’ is carried out with the main objective to analyse the tourists perception in terms of satisfaction on the existing tourism facilities and services. The study focuses on tourist satisfaction relating to quality of various tourist services such as food, transport, accommodation, etc. Poor and inadequate infrastructure facilities and management, non availability of basic facilities in tourist place, lack of domestic and international airport, inadequate transport system, lack of requisite hotel accommodation etc., make most of the tourist centres inaccessible to both domestic and foreign tourists. The satisfaction of a tourist is important for the success of the industry. Thus, the researcher took interest in researching this topic further.
Cultural Influences on Consumer Behaviour
Authors: S Rishab Mishra
Published: October 2024

This study examines the distinctions between consumer behaviour and individuality versus collectivism in regard to the buying of cars. The author of this study examined various stages of the decision-making process for consumers. Process and determined any potential distinctions between individualist and collectivist customers, as well as how it impacts the decision to buy. Drawing from a sample of 211 Australian-born individualist respondents, backgrounds that are collectivist (of Asian descent), a recognized scale (Cultural Values Scale: Singelis, Triandis, Bhawuk, If the respondents are in agreement, & Gelfand, 1995) was utilized to validate the cultural values among the participants. With the specific group (for example, Australian-born individuals who value individuality and Asian-born individuals who value collectivism). The independent sample t-test was utilized to evaluate the hypotheses. The findings showed that there were no variations in There were distinctions in the individuality shown by respondents who were born in Asia and Australia. Between these two groups in terms of collectivism, with Asian-born individuals scoring higher on a collective mindset. The findings also revealed that Asian-born consumers involve several brands and are more brand aware. Friends and family before making decisions. Conversely, Australian-born customers don’t think that decisions should be made collectively. Creating and using the internet as the primary information source. The results will offer perception into How auto manufacturers should set themselves up in terms of their marketing approaches in various cultural contexts.
Optimizing Retention in The Flexible Workplace: A Quantitative Analysis of the Mediating Role of Coping Strategies Within the Demands in Jobs-Resources Model
Authors: Abirami S , Ravishankar K
Published: October 2024

Exploring the dynamics between flexible work arrangements and employee retention, this research delves into the pivotal role of individual coping strategies as mediators. Guided by JD-R model, This study posits that flexible work arrangements serve as essential resources, easing job pressures and enabling effective coping mechanisms. Drawing on data from 280 participants across diverse industries, various JD-R variables were assessed using a 5-point Likert scale. Regression analyses illuminate significant associations between job resources, coping strategies, satisfaction of employees in job, and retention of employees. The findings will highlight the critical importance of implementing a supportive work environments that will be promoting adept stress management methods to enhance both employee well-being and organizational prosperity.
The Factors Affecting Consumers Buying Behaviour Towards Gold Jewellery in Chennai
Authors: T Karthick Raja , Sankar Ganesh R
Published: October 2024

This consider clarifies around the variables influencing buyer buying behavior towards gold adornments in Chennai, India. Chennai, a city with a wealthy social legacy and gives significance to gold, gives a distinctive advertise for understanding shopper inclinations in this industry. Marketers endeavor to get a handle on this conduct so they can way better define suitable showcasing boost that will result in expanded deals and brand dependability. Purchase motivation of consumer in jewellery sector depends on the internal variables such as Prevailing of the brand, Trust in the brand, Impact of any occasions like Festivals, Birthday, Anniversary, Wedding, Engagement etc., Celebrity Endorsement, Campaign, Brand Image, Exhibitions, Launch of new collection. Analyzing the writing from shopper behavior and showcasing, this investigate finds out a few key variables progressing obtaining choices. Certain esteem develops as a significant determinant, where buyers evaluate gold adornments not as it were as a product but too as an venture and image of status. The notoriety of brands for quality and genuineness, along with individual inclinations and social impacts, encourage choose buyer choices. Furthermore, knowledge of quality, comfort, and viable showcasing techniques plays the major part in choosing shopper obtaining behavior.
A Study on the Employees Relationship Management in Software Sector
Authors: KP Sneha , Kesavaraj Geeta
Published: October 2024

This study delves into the dynamics of employee relationship management at software sector, aiming to analyze the strategies, challenges, and overall effectiveness of the company’s approach to fostering positive relationships with its workforce. Software sector recognizes the paramount importance of  nurturing strong employee relationships in a competitive business landscape. This study explores the company’s initiatives in this regard, acknowledging the significance of a harmonious work environment for employee satisfaction and organizational success. The research approach was surveys; Employee feedback, HR policies, and management practices were scrutinized to gain a comprehensive understanding of how software sector manages and cultivates relationships with its workforce. The findings reveal that software sector, has implemented several commendable practices to enhance employee relationships. Note worthy aspects include transparent communication channels, employee recognition programs, and a supportive work culture. However, challenges such as remote work dynamics and the need for continuous adaptation to diverse employee needs were identified. Software sector, demonstrates a commitment to fostering positive employee relationships. The company’s existing practices serve as a solid foundation, but ongoing efforts are recommended to address emerging challenges and ensure sustained employee satisfaction and productivity.
Investigating Marumoside A as a Bone Sarcoma Anticancer Agent using Computational Insights
Authors: Yamoona SP , Indirani M , Pooja D
Published: October 2024

Bone sarcoma, a group of aggressive cancers arising from bone or soft tissues, remains challenging to treat effectively. This study investigates the potential of Marumoside A, a phytochemical, as a therapeutic agent against bone sarcoma using computational methods. Molecular docking was performed to explore the interactions between Marumoside A and key protein targets involved in bone sarcoma progression. Binding affinities and interaction profiles were analyzed to identify its mechanism of action. Drug-likeness and ADMET properties were assessed using SwissADME and StopTox tools, confirming compliance with pharmacokinetic and safety requirements. Marsumoside A exhibited strong binding affinities, favorable pharmacokinetic properties, and a low toxicity profile, highlighting its promise as a candidate for further preclinical evaluation. These findings underscore the therapeutic potential of Marumoside A in bone sarcoma treatment and warrant experimental validation.
Encoding Anticancer Potential of Zingerone: Bioinformatic and Molecular Docking Analysis Targeting Liver Cancer
Authors: Nitharsana M , Indirani M
Published: October 2024

Liver cancer is the third-leading cause of cancer death globally, requiring research on molecular mechanisms for sustainable prevention and treatment. With expensive conventional drugs and severe side effects, novel medications are needed. Therefore, in the current investigation employing a bioinformatic approach, we explored the bioactive phytocompound zingerone for its anticancer efficacy targeting liver cancer. The study analyzed phytocompounds’ drug-like nature using SWISS ADME, finding them orally available and meeting Lipinski, Ghose, Veber, Egan, and Muegge rules. They showed good ADMET properties and strong interactions with apoptotic regulator target proteins, making them safe for commercial anticancer drugs. hGLUT, DDEFL1, HBx, BCl2 , AFP, NF kappa, and Heat Shock Protein 70 Shows good binding affinity in the range of -5.3 to -6.0 kcal/mol. The phytocompound zingerone shows good binding affinity with all target proteins (-5.8 to -6.0 kcal/mol), thereby possessing appreciable bonded and non-bonded interactions with the binding pockets of target proteins. This study’s findings could lead to the development of promising drug candidates for liver cancer, laying the foundation for the development of novel anticancer therapeutics.
Kinderzeichnungen zum Krieg in der Ukraine. Ein forschungsmethodologisch-methodischer Beitrag zur Analyse symbolischer Ausdrucksformen
Authors: Kekeritz Mirja , Röhner Charlotte
Published: October 2024

Der Beitrag thematisiert die Rolle von Kinderzeichnungen als symbolisches Ausdrucksmittel und deren Verwendung zur Erforschung kindlicher Perspektiven als Datenmaterial in der qualitativen Sozialforschung und damit einhergehende methodologische Herausforderungen. Im Kontext einer aktuellen Studie zu Kinderzeichnungen aus dem Ukraine-Krieg werden mittels visueller Segmentanalyse nach Breckner die Zeichnungen analysiert. Die Ergebnisse zeigen intensive Reflexionen der Kinder über die Auswirkungen des Krieges auf ihr Leben. (DIPF/Orig.)
What the Hell is "Angemessenheit" in der Forschung mit Kindern? Eine Annäherung an einen strapazierten Begriff
Authors: Velten Katrin , Höke Julia , Walther Bastian
Published: October 2024

In der Grundschul- und Kindheitsforschung mit Kindern zu forschen, ist für erwachsene Forscher:innen mit der Verantwortung für den Forschungsprozess und für die ihnen anvertrauten Kinder verbunden. Damit gehen sowohl methodische als auch ethische Herausforderungen hinsichtlich der kritischen Reflexion von Machtverhältnissen einher (vgl. z.B. Alderson/Morrow 2020). Für deren Bearbeitung und als Evaluations- und Prüfkriterium wird der normative Begriff der Angemessenheit angeführt, der sich im Hinblick auf die „doppelte konstituierende Rahmung in Forschungssituationen mit Kindern“ (Nentwig-Gesemann 2022, S. 84) nicht nur auf das forschende Handeln, sondern auch auf das Handeln in Erwachsenheit bzw. in generationaler Ordnung richtet, inhaltlich jedoch häufig unbestimmt bleibt. Zur Annäherung an Angemessenheit betrachten die Autor*innen den Begriff hinsichtlich folgender drei Leitmotive, die für Forschungssettings mit Kindern relevant sind: Wahrnehmung und Anerkennung von Kindern und ihren Perspektiven, Eröffnung von Handlungsspielräumen; Beachtung forschungsinhärenter Prinzipien, wissenschaftliche Gütekriterien und Verfolgen eigener Forschungsfragen; Berücksichtigung der Bedingungen des Forschungsfelds, z.B. Schutz des Kindeswohls, organisatorisch-formale Anforderungen und Sicherung des Feldzugangs. Sie entfalten daran orientiert eine Reflexionsfolie zur Bestimmung von Angemessenheit in der Forschung mit Kindern und analysieren das Zusammenspiel der benannten Leitmotive in der konkreten Forschungspraxis beispielhaft anhand einer Interviewsequenz. Die Reflexionsfolie kann als qualitätssichernde Maßnahme Anregungen liefern für die Betrachtung von Forschungsprojekten der Grundschul- und Kindheitsforschung und bietet Potenzial für die Weiterentwicklung professioneller Forschungskompetenzen. (DIPF/Orig.)
Perspektiven von Schüler:innen bei der Bearbeitung von Aufgaben. Forschungsergebnisse zur interaktiven Aufgabenbearbeitung im sprachlichen Anfangsunterricht
Authors: Last Sandra
Published: October 2024

In diesem Beitrag werden ausgewählte Ergebnisse der abgeschlossenen Dissertationsstudie „Interaktive Aufgabenbearbeitung im sprachlichen Anfangsunterricht“ (Last 2023) vorgestellt und hinsichtlich der Perspektiven von Schüler:innen beleuchtet. Mittels eines rekonstruktiven und interpretativen Forschungsansatzes wurde untersucht, wie Schüler:innen fachdidaktisch gerahmte Lese- und Schreibaufgaben kooperativ bearbeiten. Das Gesamtkorpus von 25 Videoaufnahmen wurde zu einem Analysekorpus von 14 Videoaufnahmen reduziert und im Forschungsprozess interaktionsanalytisch ausgewertet. Die Ergebnisse weisen Prozessmerkmale sowie aufgaben- und schriftbezogene Handlungen von Erstklässler:innen aus, die eine Annäherung an ihre Perspektiven bei der fachlichen Aufgabenbearbeitung ermöglichen. (DIPF/Orig.)
Kinderleicht erklärt?! Die Adressierung von Kindern in krisenbezogenen Erklärvideos am Beispiel eines "Checker Tobi"-Videos
Authors: bauer Angela , Stoeck Janine
Published: October 2024

Erklärvideos sind Teil der Alltagswelt von Kindern (KIM-Studie 2022). Im Bereich der wissenschaftlichen Forschung werden Erklärvideos in ihrer didaktischen Funktion als neues Bildungsmedium diskutiert. Mit Blick auf die implizite Erklärpraxis spezifischer Erklärvideos für Kinder interessiert sich der Beitrag für die Adressierungen der Zielgruppe sowie den darin enthaltenen Konstruktionen von Kindern und Kindheit. Vor dem Hintergrund bisheriger Forschung zu Kinderratgebern, -wissenssendungen und -werbespots sowie einer eigenen explorativen Rekonstruktion von Auszügen aus einem „Checker Tobi“-Video wird die den Adressierungen eingeschriebene pädagogische Konstruktion von Kindern und Kindheit diskutiert. (DIPF/Orig.)