bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-healing cementitious composites incorporating innovative materials
Authors: Sherir Mohamed A. A.
Published: June 2021

Discovering new cement based materials characterized by higher durability and longer service life is crucial for sustainable infrastructure. Engineered Cementitious Composite (ECC) with high potential of micro-crack healing can enhance ductility/durability of concrete structures. However, low water-to-cement ratio in ECC matrix in addition to the lack of cementitious properties of newly formed healing-products in micro-cracks could be an obstacle to implementing continuous hydration to stimulate self-healing and stop re-opening of old healed micro-cracks during re-loading. MgO-type expansive agent (MEA), widely used to compensate effectively autogenous shrinkage in mass concrete, can be used to eliminate such obstacles and to induce self-healing. This research studied self-healing capability of MEA in ECC through an extensive experimental investigation and developed/proposed an ECC-MgO system. Test results indicated “900°C-2 hours of holding time-45 μm particle size” as the best calcination system based on higher MEA hydration in powder state. Additionally, 5% lightly burnt MgO combined with low-calcium Class-F-fly ash (as 55% cement replacement) was found to be a better choice in designing self-healing-ECC-MgO system in terms of lower expansion effect of MEA.
Further, self-healing property of ECC-MgO system under different environmental exposures (laboratory/water/natural(field)/autoclave curing) was investigated based on mechanical/durability properties of control/pre-cracked specimens compared with their ECC counterparts. The ECC-MgO system exhibited remarkable self-healing property in multiple-cracked/damaged specimens when test results were analyzed based on development/recovery of compressive/flexural strength/load resistance, ultrasonic pulse velocity, heat of hydration, expansion/drying shrinkage, rapid chloride permeability, sorptivity/water absorption and freeze/thaw resistance in addition to crack healing/cracking characteristics and microstructural characterizations through Thermogravimetric Analysis (TGA)/Differential Scanning Calorimetry (DSC) and Scanning Electron Microscopy (SEM). Finally, the self-healing ability of ECC-MgO system was evaluated through structural performance (regarding strength/stiffness/energy absorbing/crack-healing capacity recovery) of damaged and subsequently healed water/field cured link slabs used for joint-free bridge deck construction. Superior self-healing ability of ECC-MgO system was attributed to low MEA water demand coupled with its delayed hydration characteristics which lead to the formation of more cohesive/strong cementitious MgO crystals within crack walls (at later ages) supplementing CaCO3 precipitations (formed earlier) leading to more effective crack-healing and developing post-healed cracks at new locations upon reloading
Development and study of closure strip between precast deck panels in accelerated bridge construction
Authors: Ahmed Mahmoud Shaaban Sayed
Published: June 2021

This research investigates the use of glass fiber reinforced polymer (GFRP) bars in bridge decks and ultra-high performance fibre-reinforced concrete (UHPFRC) as filling materials in (i) panelto- panel closure strips between
transverse precast full-depth deck panels (FDDPs) supported over girders and (ii) the shear pockets for the panel-to-girder connection. The experimental research program included three phases. Phase I examined pullout strength of straight-end and headed-end GFRP bars embedded into UHPFRC to determine the required closure strip width to develop bar full strength. Phase II included the development and study of closure strip details incorporating UHPFRC as joint-filling materials and GFRP bars projecting into the joint. Three joints of width 200 mm between precast FDDPs were developed, namely: angle-shape joint (Ajoint), C-shape joint (C-shape), and zigzag-shape joint (Z-joint), with 175-mm projecting length of GFRP bars into the joint. Two series of 2500x600x200 mm one-way slabs were cast to investigate the flexural strength of the jointed precast slabs compared to cast-in-place slabs. Two types of concrete were used to fabricate the precast FDDPs, namely: normal concrete (NSC) and high-performance concrete (HPC). Correlation between experimental results and available design equations for moment and shear capacities, as well as CHBDC and AASHTO-LR applied factored design moments, was performed. All specimens failed in either flexural or flexural-shear mode outside the UHPFRC-filled joint. Phase III included testing three pairs of 3700x2500x200 mm laterally-restrained precast FDDPs incorporating the three developed joint details in the transverse direction of the girders. Each pair of specimens was tested under 600x250 mm wheel loading located beside the closure strip, considering (i) constant amplitude fatigue (CAF) loading up to 4 million cycles followed by increasing static loading to-collapse, and (ii) incremental variable amplitude fatigue (VAF) loading to-collapse. The failure mode of the tested slabs was punching shear, with the transverse UHPFRC joint diverting the extension of the punching shear plane to the adjacent precast FDDP segment. Results of fatigue load tests on the three-jointed pairs of slabs showed high fatigue performance. A new prediction model for fatigue life of the GFRP-reinforced, UHPFRC-filled jointed deck slabs was developed.
Effectiveness of English –Speaking Foreign Teachers from the Learners’ Perspective at Ho Chi Minh University of Food Industry
Authors: Huong Nguyen Giang
Published: June 2021

Ho Chi Minh  University of Food Industry (HUFI) is gradually reforming and updating English teaching methods to enhance the learners’ quality. Within this context, foreign teachers are required to teach in English speaking classes with the assistance and observation of native teachers. This study developed factors that foreign teacher influencing the learner’s favour with English. An online google form questionnaire was conducted on participants called students at HUFI. The respondents answer an open-ended questionnaire. The results will benefit English-speaking-foreign teachers (ESFTs) in terms of realizing their strengths and weaknesses. This study aimed to develop solutions to minimize disadvantageous factors and maximize benefits to motivate students toward learning English in classes with foreign teachers.
Uji Aktivitas Antiinflamasi Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Penghambatan Denaturasi Protein
Authors: Novika Dheani Sepalia , Ahsanunnisa Riska , Yani Dwi Fitri
Published: June 2021

Inflammation is a cell breakdown caused by bacteria, chemical substances, mechanical trauma and physical trauma. Testing of such anti-inflammatory activity can be done in-vitro with the method of protein denaturation using natural materials starfruit leaf (Averrhoa Oxalidaceae L.). This research aims to determine the comparison of the activity of ethanol extract in the strafruit leaf and sodium diclofenac. strafruit Leaf Ethanol extract is made with a concentration of 1 ppm, 10 ppm and 100 ppm with the comparator of sodium diclofenac. Antiinflammatory resistance is obtained by calculating the percentage of inhibition of protein denaturation. The result of a test of strafruit leaf ethanol extract (Averrhoa Oxalidaceae L.) with a value of IC50 of 20.20 μg/mL indicates an inhibitory percentage of more than 20% at the lowest concentration of 1 ppm, while IC50 sodium diclofenac of 14.93 μg/mL with an inhibitory percentage of more than 20% at 5 ppm .
Analisis Rekah Tarik Lereng Sidewall Penambangan Blok Menyango Berdasarkan Reliabilitas Kemantapan Lereng Menggunakan Metode Finite Difference
Authors: Wardana Novandri Kusuma
Published: June 2021

Analisis Probabilitas yang digunakan dalam parameter geoteknik merupakan metode yang signifikan dalam menyelesaikan permasalahan tingkat kestabilan lereng penambangan. Metode probabilitas kelongsoran yang mendasarkan distribusi nilai parameter dengan tipe data hasil uji laboratorium dan hasil investigasi lapangan sebagai analisis balik lereng penambangan. Lereng sidewall yang mengalami pergeseran bidang akibat adanya rekah tarik selebar 18 cm dengan panjang 150 meter menjadikan potensi longsor, sehingga diperlukan analisis balik kestabilan lereng. Kondisi ketidakpastian dari batuan pembentuk lereng pada saat tingkat kejenuhan naik 23 % sehingga memberikan tekanan airpori yang lebih besar. Lereng dengan geometri tinggi 10 m dan sudut lereng tunggal 50° diperlukan redesain tinggi 7 meter dan sudut lereng tunggal 42°. Hasil perhitungan FK didapatkan untuk lereng IRA adalah 1.376 dengan probabilitas kelongsoran nilai 23.12% dan overall slope dengan FK sebesar 1.40 dengan probability of failure sebesar 18.27%. Hasil distribusi variabel acak menggunakan Chi – Square didapatkan distribusi Normal dan Lognormal untuk batupasir, distibusi Normal dan Eksponensial untuk batulempung, dan distribusi Lognormal untuk batulanau.
ПРОБЛЕМИ УПРАВЛІННЯ СИСТЕМОЮ ЗАБЕЗПЕЧЕННЯ ВІЙСЬКОВИМ МАЙНОМ ВІЙСЬК (СИЛ) ЗБРОЙНИХ СИЛ УКРАЇНИ ТА ШЛЯХИ ЇХ ВИРІШЕННЯ
Authors: Кивлюк Володимир , Лазоренко Віктор , Ганненко Юрій , Лаврук Михайло
Published: June 2021

У статті на основі проведеного аналізу забезпечення військ (сил) Збройних Сил України на сучасному етапі розвитку визначені основні проблеми логістики як органу управління системою забезпечення військовим майном військ (сил) Збройних Сил України та пропонуються шляхи їх вирішення.

Розглядаються питання використання єдиних термінів та понять щодо забезпечення сил оборони в мирний час та особливий період. Автори визначають одну з головних проблем - це створення ефективної системи забезпечення сил оборони України, яка спроможна здійснювати планування та управління процесами забезпечення військ (сил) військовим майном як у мирний час, так і в особливий період та буде сумісною із системою НАТО.

Єдине ефективне функціонування системи забезпечення військовим майном військ (сил) Збройних Сил України становить актуальне завдання для органів військового управління, які організовують забезпечення Збройних Сил України.

Створення системи забезпечення військовим майном військ (сил) Збройних Сил України, як системи управління матеріальними потоками висуває завдання щодо об’єднання в єдину систему існуючих видів тилового та технічного забезпечення,  наближаючи їх до стандартів НАТО.

Система забезпечення розглядається, як методологія розробки раціональних методів управління забезпеченням військовим майном військ (сил) Збройних Сил України, направлених на оптимізацію,  з мінімальними затратами трудових і матеріальних ресурсів.

Наприкінці сформульовані напрямки подальших досліджень щодо удосконалення системи забезпечення сил оборони України.
МЕТОДИЧНІ ОСНОВИ КОМПЛЕКСНОГО ОБҐРУНТУВАННЯ ВИМОГ ДО ВІДНОВЛЮВАЛЬНОСТІ СКЛАДНИХ ТЕХНІЧНИХ СИСТЕМ
Authors: Шишанов Михайло , Кондратюк Ігор , Веретнов Андрій
Published: June 2021

У статті розглянуті методичні основи комплексного обґрунтування вимог до відновлювальності складних технічних систем військового призначення.

Запропоновано порядок проведення комплексної оцінки можливості відновлення складних технічних систем військового призначення.

Показано, що з метою вирішення цього завдання необхідно вирішити цілий комплекс задач. До основних з яких відносяться:

аналіз виходу з ладу (втрата працездатності) складних технічних систем військового призначення. Для чого необхідно провести декомпозицію;

аналіз ураження складних технічних систем військового призначення при використанні за призначенням в ході ведення бойових дій;

аналіз особливостей відновлювального ремонту та можливостей ремонтних органів;

обґрунтування взаємозв’язку між ураженістю, живучістю складних технічних систем військового призначення та їх відновлюваністю;

обґрунтувати необхідність внесення змін у нормативну документацію при обґрунтуванні вимог до відновлювальності складних технічних систем військового призначення.

Вирішення цих задач, як показано у статті, може бути на основі системного підходу, який і покладений в основу статті, результатами якої є:

запропонована класифікація можливих пошкоджень складних технічних систем військового призначення в процесі експлуатації;

розглянута методика функціонально-морфологічної декомпозиції складних технічних систем військового призначення;

розглянуті основні особливості відновлювального ремонту складних технічних систем військового призначення;

визначено взаємозв’язок відновлювальності та живучості складних технічних систем військового призначення.

Показано, що розглянуті методичні основи являються основою для обґрунтування вимог до ремонтопридатності складних технічних систем військового призначення.
浅谈数据流技术在电网自动化中的应用
Authors: 何 鼎
Published: June 2021

在电信业和金融业中，数据流技术早已得到应用，该技术具有数据全周期处理能力，应用价值显著。文中简要阐述了数据流技术，分析了数据流系统构建方法，说明电网自动化建设中数据流技术的应用情况，并对技术应用前景进行展望。
浅析智慧城市中5G移动通信网络规划
Authors: 张 志成
Published: June 2021

在社会快速发展的推动下，为科学技术的发展带来了良好的机遇，为智慧城市的建设起到了积极的推动作用，在这种形势下有效的促进了城市各类资源利用效率的提升，带动了城市管理服务工作整体水平的提高，在解决城市病的问题方面发挥出来重要的影响作用。5G移动通信技术因为具有传输效率高、网络容量大、功能延时低的优越性，所有受到了人们的广泛青睐，可以实现万户互联，是当前实惠城市神经系统，充分的结合实际情况和需要来对5G移动通信网络方案加以设计，是当前我国通信行业最为重要的一个问题。
防止桥头跳车病害施工技术探析
Authors: 李 巍
Published: June 2021

桥头跳车病害作为公路桥梁工程中常见的病害之一，已经严重影响到桥梁的安全运营，严重的桥头跳车病害不仅会破坏路桥结构，影响结构稳定性和安全性，还会损伤车辆底盘结构，缩短车辆使用寿命；为了进一步防治和解决桥头跳车病害，文中从桥头跳车病害成因和原理出发，从三方面给出了具体的跳车病害防治解决措施，希望为桥头跳车病害治理提供理论依据。
地铁车站深基坑施工变形监测研究
Authors: 黄 彦鑫
Published: June 2021

近年来，我国社会经济在多方面利好因素的影响下整体水平得到了显著的提升，从而为城市建设工作的实施带来了良好的机遇，与此同时城市人口数量也在不断的增加，这样就对城市交通系统提出了更高的要求。为了切实的解决当前城市交通网络的压力问题，提升土地资源的利用效率，各个地区大量的地铁工程被建造出来，为民众的生活带来了诸多的便利。就当前实际情况来说，世界范围内已经大约有一百座城市建造了地铁工程，不但有效的缓解了当前城市内的交通压力，并且也为民众的生活提供了良好的便利。但是因为地铁工程的建造都是在地下空间进行的，再加上工程施工工作量较为巨大，所以往往会在施工过程中遇到诸多的危险情况，所以施工单位需要加强施工的监测力度，尽可能的避免各类施工质量问题的发生。
苯酐气体冷却器堵塞后的煮洗和吹扫措施分析
Authors: 范 雷
Published: June 2021

基于苯酐这一装置，在出现气冷堵塞现象之后，会极大降低生产产量。文章首先概述了苯酐工艺流程，然后探究了苯酐气体冷却器，其中包括工作原理、气体冷却器堵塞、堵塞之后的煮洗措施，以期能为有关人士提供参考。
乡村振兴规划体系与关键技术研究
Authors: 杨 玲
Published: June 2021

以全国乡村振兴的总体战略规划为基础遵循和工作指导，确保农村经济社会发展的规划、建设要与乡村振兴面临的实际情况、理论认识、体制机制等方面深度的结合起立，确保各类规划体系真正的落到实处。尤其在我国目前的经济社会、科学技术的高速进步和快速发展的今天，乡村振兴规划和科技工作需要全面的协同配合，这样才能在实践中快速的、有效的推动和实现农村的振兴和稳定繁荣的发展。
土建工程建设中的高支模施工技术
Authors: 黄 志强
Published: June 2021

在社会快速发展的推动下，我国各个领域的发展都取得了良好的成绩，从而为土建工程的稳步健康发展带来了良好的机遇。在土建工程施工建造中涉及到的层面较多，具有一定的复杂性，所以需要施工工作人员具备较强的专业水平，并且在施工过程中严格遵从规范要求来实施各项施工工作，这样才能从根本上对工程施工工作的质量和安全加以保证。在实际组织实施建筑工程施工建造工作的时候，高支模施工技术的作用是非常重要的，将高支模施工技术加以合理地运用能够切实的提升土建工程施工工作的整体效率和效果。所以施工单位需要对高支模施工技术加以重点关注，从各个细节入手对高支模施工技术整体水平进行不断提升，这样才能推动整个土建工程施工行业的未来良好发展。
HERNÁN MALO, UNA ÉPOCA
Authors: Valencia José
Published: June 2021

Antes que Hernán Malo y después de Hernán Malo, la historia de la Pontificia Universidad Católica del Ecuador ha quedado signada por su paso; y es que Hernán Malo no fue "tan sólo" el hombre: un ser conflictivo en una época de arduas jornadas. Su sombra abarcó y alumbró un proceso, una era, una estación en la vida de esta Alma Mater.Las raíces de la etapa de Hernán Malo se remontan a la esencia misma de la universidad ecuatoriana, en general, y de la Universidad Católica, en particular. La universidad ecuatoriana, fiel reflejo de una sociedad donde jamás llegó a imponerse hegemónicamente fuerza social alguna, se atascó al igual que aquella, en conflictos de largo aliento, sin definiciones y con espesas disquisiciones, donde a la postre sólo sacaron provecho quienes se interesaban en distraer la atención universitaria de la verdadera lucha.
LOS SUEÑOS DE HERNÁN MALO
Authors: Paladines-Escudero Carlos
Published: June 2021

"Es preciso soñar. Hay desacuerdo respecto al desacuerdo entre el sueño y la realidad. Mi sueño puede superar el curso natural ele los acontecimientos y puede también cambiar el rumbo ele una dirección que el curso ele los acontecimientos no podrá seguir nunca. En el primer caso, el sueño no es nada insano; incluso puede sostener y reforzar la energía del trabajador.... para emprender y llevar a término amplios y costosos trabajos en el campo de las artes, la ciencia y la vicia cotidiana... El desacuerdo entre el sueño y la realidad nada tiene de nocivo, siempre y cuando el hombre que sueña crea seriamente en su sueño, observe atentamente la vida, compare sus observaciones con sus castillos de naipes y, de una manera general, trabaje concienzudamente en la realización de su sueño (1)".
Järjestökoulutus kestävän elämän tukijana
Authors: Hannukainen Kristiina , Fields Marion
Published: June 2021

Kestävyyskysymykset ovat kansalaisjärjestöille yhä tärkeämpiä. Sivistyminen kestävään elämään on niille ennen kaikkea tiedon asia. Näin osoittaa analyysi Opintokeskus Siviksen jäsenjärjestöjen koulutuksesta. Tiedon rinnalle tarvitaan toimintaa.
Kansalaistieteen kutsu
Authors: Heikkinen Anja , Pätäri Jenni
Published: June 2021

Millaiseen keskusteluun kansalaistiede tiedepoliittisena iskusanana tai historiallistavan tarkastelun kohteena kutsuu? Voisivatko juhlavuottaan viettävät Sivistystyön Vapaus ja Vastuu (SVV) -yhteistyöohjelma ja Aikuiskasvatus toimia kansalaistamista koskevan julkisen keskustelun ja toiminnan foorumeina?
Kasvatusteoria ja itsekasvatus nykyisyyden kritiikkinä
Authors: Jokisaari Olli-Jukka
Published: June 2021

Teos täyttää suomenkielisen tietokirjallisuuden aukkoa, sillä kasvatusteoriaa kokoavasti käsitteleviä ajantasaisia teoksia ei liikaa ole. Otsikon kuvaama aikajänne on aavistuksen mahtipontinen, kun ottaa huomioon, että pariin sataan sivuun on puristettu valikoidusti eri aikojen kasvatusfilosofian ja -teorian käsittelyä.
Development of a New Data Processing System for Increasing the Accuracy of a Levitation Mass Method (LMM) based Measurement
Authors: Satria Eko , Hendro Hendro , Fujii Yusaku , Djamal Mitra
Published: June 2021

Levitation Mass Method (LMM) is the method as a material tester to evaluate the mechanical response of general objects against impact forces. In this method, a mass is made to collide with material to be tested and the impulse, i.e. the time integration of the impact force, is measured highly accurately as a change in momentum of the mass. To realize linear motion with sufficiently small friction acting on the mass, a pneumatic linear bearing is used. The inertial force acting on the mass is calculated from the velocity of the mass. The velocity is determined, highly accurately by means of measuring the Doppler shift frequency of a laser light beam reflected on the mass using an optical interferometer. To determine the Doppler frequency shift for LMM data processing, the method for estimating the frequency is necessary. Several methods have been developed to estimate the frequency for the LMM data processing with high accuracy, i.e. Zero-Crossing Average Method (ZAM), Zero-Crossing Fitting Method (ZFM), Sine Wave Fitting, and Zero-crossing Sine Wave Fitting. All methods realized using the zero-crossing point of the waveform obtained from the digitizer. A better method to estimate frequency on the digitized waveform will enable higher precision for a more accurate result. In this research, a new method that can improve the accuracy has been developed. The program was developed using data segmentation to obtain the frequency of the digitized waveforms. The developed program has the smallest error ( 1,98 X 10^-10 for N= 200) compare to other methods (2,31 X 10-3 for ZAM; 1,10X10-3 for ZFM; and 8,69 X10-4 for Zero-crossing Sine Wave Fitting).
Elaboração, avaliação mercadológica e análise sensorial de pudim gelado sem lactose
Authors: Vieira Fernanda de Oliveira , Santos Suelem Vieira dos , Tombini Caroline , Moratelli Priscila Favero , Machado Junior Francisco Roberto da Silva , Zanetti Micheli , Dalcanton Francieli
Published: June 2021

O desenvolvimento de novos produtos se faz necessário para suprir a demanda do consumidor, que cada vez mais apresenta anseios e necessidades específicas. Nesse sentido, o mercado de produtos zero lactose se apresenta em constante crescimento, visando atender essa demanda. Estima-se que a cada 10 brasileiros, 7 são intolerantes, sendo que para alguns, a intolerância está presente desde os primeiros momentos de vida. Diante disso e buscando avaliar o atual cenário mercadológico no âmbito de produtos sem lactose, aplicou-se um questionário online e foi realizada a elaboração de uma sobremesa do tipo pudim gelado sem lactose, o qual passou por avaliação sensorial e de intenção de compra como método de estudo para investigar o potencial mercadológico deste produto. O questionário online resultou em 521 respostas e apontou que 22,8% eram intolerantes a lactose, enquanto 71,2% não possuíam nenhuma intolerância. A análise sensorial do pudim gelado sem lactose apresentou uma aceitação acima de 70% em todos os atributos na escala hedônica e 92% dos voluntários responderam que certamente ou provavelmente comprariam o produto. Conclui-se assim, que o pudim zero lactose desenvolvido agradou os avaliadores tanto intolerantes, quanto não intolerantes, apresentando uma alternativa promissora no cenário de produtos sem lactose pois, além disso, apresentou custo similar a um pudim tradicional.
A prática influenciando a formação e a aprendizagem na Educação Profissional e Tecnológica
Authors: Costa Temilson , Brasileiro Filho Samuel , Lemos Pedro Bruno Silva
Published: June 2021

A relação entre a teoria e a prática caracteriza e define ações pedagógicas que possibilitam melhor compreender o processo de ensino e aprendizagem. Por meio deste trabalho, tentou-se encontrar respostas que estabeleçam análises reflexivas sobre os fatores que orientam o entendimento docente sobre a ação pedagógica e os benefícios que as atividades práticas desenvolvem na aprendizagem. Isto posto, abordou-se uma proposta de elucubração do viés acadêmico, intencionando-se investigar as atividades práticas desenvolvidas na Educação Profissional e Tecnológica. Ademais, articulou-se a teoria e a prática no processo de ensino e de aprendizagem, de forma a mobilizar os saberes críticos necessários à formação pessoal e profissional. Nesse contexto, buscou-se refletir se as atividades práticas, na Educação Profissional e Tecnológica, protagonizam uma prática fundamentada na teoria. Além disso, verificou-se a importância da teoria se relacionando com a prática no processo de ensino e de aprendizagem e identificou-se as variáveis e os condicionantes que orientam o fazer pedagógico dos docentes na aplicação de atividades práticas. O presente artigo é parte dos resultados de nossa pesquisa de mestrado e fundamenta-se numa abordagem metodológica baseada numa pesquisa bibliográfica, apoiada por uma investigação qualitativa, que explora e reflete sobre o fazer pedagógico na Educação Profissional e Tecnológica. Nessa esteira, sintetizam-se algumas reflexões sobre os aspectos analisados dessa temática, de acordo com o pensamento de autores, como Barato (2002, 2008, e 2011), Saviani (2007), Gamboa (2010), Pimenta (2009), Silva (2013), Guimarães (2014), dentre outros, e apresentam-se algumas ações de atividades práticas realizadas no IFCE Campus Baturité. Como resultado, este trabalho contribui para a implementação de aulas dinâmicas, que possibilitam, além dos debates e discussões em sala de aula, realizar atividades que contextualizem a aprendizagem, tanto na academia, como também, no mercado de trabalho. Desse modo, concluiu-se que as experiências práticas realizadas em diversos cursos do Instituto Federal de Educação, Ciência e Tecnologia do Estado do Ceará, Campus Baturité, fundamentam o trabalho e confirmam a importância da relação teoria e prática no processo de ensino e de aprendizagem.
Aplicabilidade clínica das células-tronco mesenquimais indiferenciadas do tecido adiposo para cirurgias de regeneração óssea de maxila e mandíbula atrófica
Authors: Balderrama Ísis de Fátima , Ferreira Rafael , Leão Moira Pedroso , Marcantonio-Júnior Elcio
Published: June 2021

Objetivo: Esta revisão de literatura tem como objetivo realizar uma busca estratégica de artigos científicos sobre a aplicabilidade das células-tronco do tecido adiposo associado aos enxertos em cirurgias de regeneração óssea em maxila e mandíbula atrófica. Metodologia: Foi realizada uma estratégia de busca em quatro bases de dados (PubMed, Embase, Web of Science e Cochrane Library) por meio do cruzamento de diferentes descritores de acordo com a estratégia PICO. Resultados: Foram recuperados 206 artigos, porém, de acordo com os critérios de inclusão e exclusão desta revisão, um total de 9 artigos foram selecionados para uma análise crítica e analítica. Os resultados dos artigos desta revisão demonstraram que para a obtenção das células-tronco mesenquimais (CTMs) do tecido adiposo, pode ser coletada através do tecido abdominal (TA) ou pela bola de Bichat (BB). Estudos que realizaram a caracterização das células presentes no tecido adiposo, resultam em expressão de marcadores de células mesenquimais. Para a transplantação em abordagem clínica, as cirurgias de levantamento de seio maxilar, regeneração óssea em pré-maxila e mandíbula atrófica, assim como fratura de côndilo, demonstraram bons resultados quando as CTMs ou com a fração vascular estromal (FVE) foram associados com enxerto autógeno, xenógeno ou aloplástico. Conclusão: Apesar da limitada evidência científica, a abordagem celular com FVE e as CTMs derivadas do TA ou BB demonstram ser seguras e eficazes quando associadas com enxerto autógeno, sintético, alógeno ou xenógeno, favorecendo o potencial osteogênico nas cirurgias de regeneração óssea.
Os significados do pré-natal atribuído por gestantes realizado por enfermeiros
Authors: Silva Dulcinéia Pinho , Silvestre Grasiela Cristina Silva Botelho , Castelli Laíza Strinta , Silva Fabiane Verônica , Vicente Jefferson Tennesse da Silva , Faria Nemora Barros , Rocha Roseany Patrícia Silva
Published: June 2021

Introdução: O acompanhamento de pré- natal deve pautar-se na qualidade da assistência, baseando-se na integralidade e humanização para promoção da saúde, prevenir de doenças ou agravos e recuperação da saúde materna e neonatal. A valorização da opinião da mulher acerca das decisões que envolvem seu plano terapêutico é relevante e oportuna, sendo assim, o presente artigo tem como objetivo compreender os significados atribuídos por gestantes ao pré-natal realizado por enfermeiros. Metodologia: Trata-se de estudo exploratório, descritivo, de abordagem qualitativa, com doze gestantes cadastradas em uma Estratégia Saúde da Família da região médio norte do estado de Mato Grosso. A coleta de dados deu-se por intermédio de entrevistas semiestruturadas, analisadas conforme a análise de conteúdo do tipo temática. Resultados: dos achados emergiram duas categorias temáticas: a) significando o período gestacional e o acompanhamento de pré-natal; e b) a qualidade da consulta de enfermagem no pré-natal. Conclusão: os resultados sugerem que o pré- natal realizado pelo profissional enfermeiro e a importância da qualidade do pré-natal foram considerados pelas mulheres como um processo importante e necessário. As mulheres sentiram-se motivadas pelo cuidado e atenção dos enfermeiros nas consultas, sanando suas inquietações. Além disso, robustece a discussão sobre iniciativas de empreendedorismo na enfermagem e o fortalecimento da categoria, e da identidade profissional, que vem assumindo espaços nos diversos serviços de saúde.
Use of colored agrotextiles and length of stay in the cultivation of yellow melons
Authors: Oliveira Odair Honorato de , Queiroga Roberto Cleiton Fernandes de , Costa Franciscleudo Bezerra da , Mesquita Evandro Franklin de , Silva Francisco Alves da , Silva Higínio Luan Oliveira , Silva Alvaro Gustavo Ferreira da
Published: June 2021

The coverage of plants with agrotextiles of different colors and length of stay may influence the productivity of the crop. The objective of this study was to evaluate the influence of the use of colored agrotextiles and their length of stay on the cultivation of melon plants in the conditions of the semiarid region of Paraíba. The experiment was fulfilled out at the Experimental Farm of the Federal University of Campina Grande, located in the municipality of São Domingos – PB.  The treatments were distributed in a randomized block design in a 4 x 4 factorial scheme, with four repetitions and consisting of four colors of agrotextile (orange, white, gray, and blue) and four lengths of stay (15, 18, 21, and 24 days after transplanting).  The following characteristics were evaluated: active photosynthetic radiation, average temperature, number of fruits per plant, average fruit mass and total productivity. The use of colored agrotextiles associated with the length of stay promoted a change in the production characteristics of the yellow melon fruits. The highest productivity, number of fruits, and mass of the melon fruits were obtained when the plants were covered with the orange-colored agrotextile at 15, 18, and 24 days after transplantation, respectively. The long stay of the agrotextile affected the content of total soluble solids.
Usaha Tani Padi Sawah Berbasis Agrosilvopastura Di Kampung Walal Distrik Salawati Kabupaten Sorong
Authors: Ali Akhmad , Maruapey Azis , Soekamto Mira Herawati
Published: June 2021

Program KemitraanÂ  bagi Masyarakat StimulusÂ  (PKMS) Pemberdayaan Kelompok Usaha Tani Padi Sawah berbasis Agrosilvopasture di Kampung Walal Distrik Salawati Kabupaten Sorong merupakan suatu penelitian yang diangkat berdasarkan beberapa permasalahan yang dihadapi petaniÂ  padiÂ  sawahÂ  di Kampung Walal. Permasalahan yang dihadapi kelompok tani (mitra)Â  adalah pemanfaatan lahanÂ  dan limbah kotoran ternak yang belum optimal serta tingkat penguasaan teknologi yang masih rendah di kalangan petani Kampung Walal. Berbagai solusi yang ditawarkan dalam menghadapi permasalahan yang dihadapi petani diantaranya dengan pendekatan percepatan alih teknologi dan peningkatan pengetahuan melalui penyuluhan, dialog aktif,Â  pelatihan dan pendampingan, sehingga diharapkan dapat mempunyai keluaran berupaÂ  peningkatan kemampuan pengelolaan lahan berbasis agrosilvopastur, peningkatanÂ  teknologi yang dapat menghasilkanÂ  sumber energi dan peningkatan pendapatan petani.
Pengentasan Buta Aksara Melalui Pembelajaran Calistung di Kampung Nanggou Distrik Sausapor Kabupaten Tambrauw Papua Barat
Authors: Sangadji Zulkarnain , Febriadi Ihsan , Rosalina Febrianti
Published: June 2021

Pemberantasan buta aksara adalah salahsatu bagian integral terkait pengentasan masyarakat dari kebodohan, kemiskinan, dan keterbelakangan, serta ketidakberdayaan dalam pengembangan kualitas sumber daya manusia di Indonesia. Distrik Sausapor sebagai Distrik yang berfungsi sebagai Ibu Kota Kabupaten Sementara Kabupaten Tambrauw menuntut masyarakatnya khususnya di daerah Pesisir yang masih memiliki Pendidikan rendah dan kemampuan berkomunikasi yang rendah dengan kemampuan Calistung yang masih sangat membutuhkan pemberdayaan, khususnyaÂ  pembelajaran membaca, menulis dan menghitung. Sebagai Kabupaten yang memiliki jumlah penduduk Buta Aksara terbanyak di Papua Barat, tentunya Pembelajaran Calistung ini sangat perlu dilakukan. Hal ini tentunya akan berdampak positif terhadap kemampuan berkomunikasi masyarakat. Berdasar pada hal tersebut maka dilakukan kegiatan berupa pengentasan buta aksara melaluiÂ  pembelajaran calistung (membaca, menulis, dan berhitung) secara berkelompok dengan tiga tahapan yang dimulai darin tahap persiapan, pelaksanaan hinggaÂ  tahapan analisis data. Selanjutnya demi keberlanjutan kegiatan pemberdayaan masyarakat tersebut akan dipilih beberapa calon tutor yang akan melanjutkan kegiatan belajar kelompok yang telah dibentuk. Demi meningkatkan kemampuan berkomunikasi masyarakat, metode pembelajaran yang berbasis komunikatif dilakukan agar mampu melatih masyarakat dalam berinteraksi satu sama lainnya. Kemampuan aksara masyarakat diukur melalui pre test (sebelum kegiatan) dan post test (setelah kegiatan). Hasil kegiatan menunjukkan bahwa terjadi peningkatan kemapuan Calistung warga belajar setelah dilakukan proses belajar mengajar oleh tutor. Dimana kemampuan membaca, menulis, dan berhitung sebelum kegiatan adalah 20%, 28%, dan 19% dan meningkat manjadi 84%, 85%, dan 78% setelah kegiatan. Adapaun kegiatan ini tidak akan berjalan lancer jika tidak ada Kerjasama yang baik dari berbagai pihak dan tentunya kesadaran belajar yang tinggi dari warga belajar harus diciptakan agar tujuan kegiatan bisa tercapai dengan baik.
Analisis Malware dengan metode Surface dan Runtime Analysis
Authors: Panjaitan Febriyanti , Yudiastuti Helda , Ulfa Maria
Published: June 2021

Malware salah satu virus yang memiliki banyak cara dalam menginfeksi sebuah data  dan dapat memberikan kerusakan yang berbahaya, seperti yang terjadi pada salah satu rumah sakit ternama, dimana malware menyerang seluruh data yang ada sehingga data tidak dapat diakses kembali oleh pihak yang terkait. Malware bukan hanya menyerang data, tetapi dapat merusak sistem operasi yang sedang digunakan karena rentan untuk disusupi, salah satunya adalah sistem operasi windows. Malware sangat sulit di intifikasi dengan file data yang asli jika tidak menggunakan bantuan tools analisis, dengan hal tersebut penelitian akan melakukan analisis dan pengujian terhadap tingkah laku malware, sehingga dapat diketahui pola dan jenis malware dengan 2 metode analisis yaitu  metode surface analisis  (Pestudio, Strings, Exeinfo dan Virus) dan runtime analisis ( Regshot, CaptureBAT, Noriben Malware Analysis). Analisa yang dilakukan menciptakan lingkungan kerja sebagai tempat uji coba, sehingga tidak menggangu sistem utama yang telah  berjalan. Dengan uji coba yang dilakukan, jadi didapatkan bahwa File dengan nama "games.exe”  dapat dikatakan malware karena memiliki strings dan dapat menggandakan diri ke folder system32 yang dibuktikan dengan MD5.
MEMBANGUN VIRTUAL TRAVELING KABUPATEN KUTAI KARTANEGARA (KUKAR) SEBAGAI MEDIA WISATA VIRTUAL DI MASA PANDEMI
Authors: Lailiyah Siti , Hasiholan Jundro Daud , Jahriansyah Muhammad
Published: June 2021

large-scale social restriction make tourists no longer able to visit tourist objects freely like they used to. Research to develop Virtual Traveling of Kutai Kartanegara is one of the media that will be used to support tourism in Kutai district during the Covid-19 pandemic, in a fun way so that it will attract millennials to get to know tourism in Kutai Kartanegara (KUKAR) so it is hoped that tourism objects that will become candidates for the new capital city of Indonesia which is better known in the archipelago. Virtual Traveling is an alternative for traveling without having to go far to the city. Virtual tourism can be an interesting medium to introduce various tourist objects in KUKAR through interactive applications. The purpose of establishing Kutai Kartanegara Virtual Traveling is that KUKAR tourism will be easily introduced to the public with interactive and interesting media. In this research, the method used to build a tourism application is multimedia life-cycle development, starts from concept, design, materials collecting, assembly, testing, and distribution. The result, this virtual tourism application can be used as promotional media for the KUKAR Tourism Department
WHY CIVILIZATIONS COLLAPSE?
Authors: Martin-Merino Mario
Published: June 2021

One of the questions we can ask ourselves before addressing the analysis of the issue to be dealt with in this work, in which mention will be made of some theories that have sought a satisfactory answer, is what we understand as "collapse". If we check its definition in a dictionary its first meaning is as follows: "Destruction, ruin of an institution, system, structure, etc." This definition can be considered somewhat vague, and we normally associate "collapse" with something negative.
Beyond Microsatellite Instability: Intrinsic Disorder as a Potential Link Between Protein Short Tandem Repeats and Cancer
Authors: Verbiest Max A. , Delucchi Matteo , Bilgin Sonay Tugce , Anisimova Maria
Published: June 2021

Short tandem repeats (STRs) are abundant in genomic sequences and are known for comparatively high mutation rates; STRs therefore are thought to be a potent source of genetic diversity. In protein-coding sequences STRs primarily encode disorder-promoting amino acids and are often located in intrinsically disordered regions (IDRs). STRs are frequently studied in the scope of microsatellite instability (MSI) in cancer, with little focus on the connection between protein STRs and IDRs. We believe, however, that this relationship should be explicitly included when ascertaining STR functionality in cancer. Here we explore this notion using all canonical human proteins from SwissProt, wherein we detected 3,699 STRs. Over 80% of these consisted completely of disorder promoting amino acids. 62.1% of amino acids in STR sequences were predicted to also be in an IDR, compared to 14.2% for non-repeat sequences. Over-representation analysis showed STR-containing proteins to be primarily located in the nucleus where they perform protein- and nucleotide-binding functions and regulate gene expression. They were also enriched in cancer-related signaling pathways. Furthermore, we found enrichments of STR-containing proteins among those correlated with patient survival for cancers derived from eight different anatomical sites. Intriguingly, several of these cancer types are not known to have a MSI-high (MSI-H) phenotype, suggesting that protein STRs play a role in cancer pathology in non MSI-H settings. Their intrinsic link with IDRs could therefore be an attractive topic of future research to further explore the role of STRs and IDRs in cancer. We speculate that our observations may be linked to the known dosage-sensitivity of disordered proteins, which could hint at a concentration-dependent gain-of-function mechanism in cancer for proteins containing STRs and IDRs.
MicroRNA-124-3p Plays a Crucial Role in Cleft Palate Induced by Retinoic Acid
Authors: Yoshioka Hiroki , Mikami Yurie , Ramakrishnan Sai Shankar , Suzuki Akiko , Iwata Junichi
Published: June 2021

Cleft lip with/without cleft palate (CL/P) is one of the most common congenital birth defects, showing the complexity of both genetic and environmental contributions [e.g., maternal exposure to alcohol, cigarette, and retinoic acid (RA)] in humans. Recent studies suggest that epigenetic factors, including microRNAs (miRs), are altered by various environmental factors. In this study, to investigate whether and how miRs are involved in cleft palate (CP) induced by excessive intake of all-trans RA (atRA), we evaluated top 10 candidate miRs, which were selected through our bioinformatic analyses, in mouse embryonic palatal mesenchymal (MEPM) cells as well as in mouse embryos treated with atRA. Among them, overexpression of miR-27a-3p, miR-27b-3p, and miR-124-3p resulted in the significant reduction of cell proliferation in MEPM cells through the downregulation of CP-associated genes. Notably, we found that excessive atRA upregulated the expression of miR-124-3p, but not of miR-27a-3p and miR-27b-3p, in both in vivo and in vitro. Importantly, treatment with a specific inhibitor for miR-124-3p restored decreased cell proliferation through the normalization of target gene expression in atRA-treated MEPM cells and atRA-exposed mouse embryos, resulting in the rescue of CP in mice. Taken together, our results indicate that atRA causes CP through the induction of miR-124-3p in mice.
Recent Advances in the Roles of Autophagy and Autophagy Proteins in Host Cells During Toxoplasma gondii Infection and Potential Therapeutic Implications
Authors: Subauste Carlos S.
Published: June 2021

Toxoplasma gondiiis an obligate intracellular protozoan that can cause encephalitis and retinitis in humans. The success ofT. gondiias a pathogen depends in part on its ability to form an intracellular niche (parasitophorous vacuole) that allows protection from lysosomal degradation and parasite replication. The parasitophorous vacuole can be targeted by autophagy or by autophagosome-independent processes triggered by autophagy proteins. However,T. gondiihas developed many strategies to preserve the integrity of the parasitophorous vacuole. Here, we review the interaction betweenT. gondii, autophagy, and autophagy proteins and expand on recent advances in the field, including the importance of autophagy in the regulation of invasion of the brain and retina by the parasite. We discuss studies that have begun to explore the potential therapeutic applications of the knowledge gained thus far.
Utilization of Crystalline and Amorphous Silica as a Sintering Inhibitor in Iron/Iron Oxide Thermochemical Water Splitting Cycle
Authors: Al-Ragom Fotouh
Published: June 2021

Hydrogen as a chemical fuel and energy carrier can provide the path to solar energy storage to overcome the intermittency issues. Hydrogen can be produced by various methods; among them is the thermochemical water splitting of metal/metal oxide reduction oxidization (redox) reactions. Many redox cycles were identified, including the non-volatile redox pair, such as the iron/iron oxide. This redox pair has the capability to produce Hydrogen with rapid reaction rates especially when it is used in powder form due to the high specific reactive surface area. Yet, this pair suffers from sintering at temperatures exceeding 500°C. Sintering adversely affects the Hydrogen production process and inhibits the recycling of the powder. To overcome sintering, experimental investigations using elemental iron and silica were conducted as detailed in this paper. The oxidation of elemental iron (Fe) powder by steam to produce Hydrogen was carried out using a fluidized bed reactor. The investigations aimed at developing a practical sintering inhibition technique that can allow repeated redox cycles, stabilize the powder reactivity, and maintain Hydrogen production. The experimental investigations involved varying the fluidized bed temperature between 630–968°C. The steam mass flow rate was set to 2 g/min. To inhibit sintering, solid-state mixing of crystalline, or amorphous silica with porous iron powder was used at various iron/silica volume fractions. The investigations showed that mixing iron with silica hinders the sintering but reduces the Hydrogen yield. Mixing iron with crystalline silica with 0.5, 0.67, and 0.75 apparent volume fraction reduces the Hydrogen yield compared to pure iron by 20, 30, and 45%, respectively. Mixing iron with amorphous silica reduces the Hydrogen yield by 35 and 45%, as compared to pure iron, for iron 0–250 and 125–355 µm particle size distribution, respectively. The Hydrogen production rate for iron/amorphous silica mixtures surpassed that of the iron/crystalline silica. Mixing iron with amorphous silica prevented sintering at elevated bed temperatures in the range of 850°C, and only clumping occurred. The clumped samples restored their original powder condition with minimum agitation. Thus, solid-state mixing of amorphous silica with iron powder can be a promising technique to retard iron/iron oxide particles sintering.
Beneficial Effect on Exercise Tolerance of a Comprehensive Rehabilitation Program in Elderly Obese Patients Affected With Heart Disease
Authors: Gondoni Luca Alessandro , Nibbio Ferruccio , Titon Annamaria
Published: June 2021

Aims: The number of elderly patients affected with multiple chronic diseases is constantly increasing. Even though multiple studies demonstrated a beneficial effect of cardiac rehabilitation, we do not have data on the outcomes in elderly patients with obesity and heart disease.

Methods: We studied 772 consecutive obese subjects (275 women; 35.6%) aged ≥70 years, affected with coronary artery disease and/or heart failure. We conducted a symptom limited exercise test at the beginning and at the end of the program, which consisted of aerobic and strength physical activity, diet, and psychological counseling.

Results: Mean body mass index (BMI) at baseline was 37.6 ± 4.4 kg/m2 and decreased to 36.4 ± 4.3 kg/m2 (P < 0.001). At baseline, attained metabolic equivalents (METs) were 4.7 ± 1.7, and by the end of the program, they were 5.6 ± 2.1 (P < 0.001). The mean improvement was 21.6 ± 21.7% (median, 17.6%; 95% CI, 20.0–23.1%). Patients over 80 years old had similar results compared to the younger ones. Diabetics did worse than non-diabetic patients: the improvement they reached was 19.4 ± 18.9% vs. 23.8 ± 23.9% (P = 0.005). The presence of heart failure was significantly related to both the baseline and final performance, but the attained improvement was significantly greater in heart failure patients: 24.3 ± 23.8% vs. 16.3 ± 15.4% (P < 0.001). No patient had adverse events related to the program.

Conclusion: This study documents a significant improvement in exercise capacity in elderly obese patients affected with heart disease who underwent a rehabilitation program.
Next Generation Sequencing Based Multiplex Long-Range PCR for Routine Genotyping of Autoinflammatory Disorders
Authors: Guzel Ferhat , Romano Micol , Keles Erdi , Piskin David , Ozen Seza , Poyrazoglu Hakan , Kasapcopur Ozgur , Demirkaya Erkan
Published: June 2021

Background

During the last decade, remarkable progress with massive sequencing has been made in the identification of disease-associated genes for AIDs using next-generation sequencing technologies (NGS). An international group of experts described the ideal genetic screening method which should give information about SNVs, InDels, Copy Number Variations (CNVs), GC rich regions. We aimed to develop and validate a molecular diagnostic method in conjunction with the NGS platform as an inexpensive, extended and uniform coverage and fast screening tool which consists of nine genes known to be associated with various AIDs.

Methods

For the validation of basic and expanded panels, long-range multiplex models were setup on healthy samples without any known variations for MEFV, MVK, TNFRSF1A, NLRP3, PSTPIP1, IL1RN, NOD2, NLRP12 and LPIN2 genes. Patients with AIDs who had already known causative variants in these genes were sequenced for analytical validation. As a last step, multiplex models were validated on patients with pre-diagnosis of AIDs. All sequencing steps were performed on the Illumina NGS platform. Validity steps included the selection of related candidate genes, primer design, development of screening methods, validation and verification of the product. The GDPE (Gentera) bioinformatics pipeline was followed.

Results

Although there was no nonsynonymous variation in 21 healthy samples, 107 synonymous variant alleles and some intronic and UTR variants were detected. In 10 patients who underwent analytical validation, besides the 11 known nonsynonymous variant alleles, 11 additional nonsynonymous variant alleles and a total of 81 synonymous variants were found. In the clinical validation phase, 46 patients sequenced with multiplex panels, genetic and clinical findings were combined for diagnosis.

Conclusion

In this study, we describe the development and validation of an NGS-based multiplex array enabling the “long-amplicon” approach for targeted sequencing of nine genes associated with common AIDs. This screening tool is less expensive and more comprehensive compared to other methods and more informative than traditional sequencing. The proposed panel offers advantages to WES or hybridization probe equivalents in terms of CNV analysis, high sensitivity and uniformity, GC-rich region sequencing, InDel detection and intron covering.