bluuebunny/crossref_metadata_2025 huggingface dataset:
Changing optical properties of black carbon and brown carbon aerosols during long-range transport from the Indo-Gangetic Plain to the equatorial Indian Ocean
Authors: Budhavant Krishnakant , Manoj Mohanan Remani , Nair Hari Ram Chandrika Rajendran , Gaita Samuel Mwaniki , Holmstrand Henry , Salam Abdus , Muslim Ahmed , Satheesh Sreedharan Krishnakumari , Gustafsson Örjan
Published: October 2024

Abstract. Atmospheric aerosols strongly influence the global climate through their light absorption properties (e.g., black carbon (BC) and brown carbon (BrC)) and scattering properties (e.g., sulfate). This study presents simultaneous measurements of ambient-aerosol light absorption properties and chemical composition obtained at three large-footprint southern Asian receptor sites during the South Asian Pollution Experiment (SAPOEX) from December 2017 to March 2018. The BC mass absorption cross section (BC-MAC678) values increased from 3.5 ± 1.3 at the Bangladesh Climate Observatory at Bhola (BCOB), located at the exit outflow of the Indo-Gangetic Plain, to 6.4 ± 1.3 at two regional receptor observatories, the Maldives Climate Observatory at Hanimaadhoo (MCOH) and the Maldives Climate Observatory at Gan (MCOG), representing an increase of 80 %. This likely reflects a scavenging fractionation, resulting in a population of finer BC with higher MAC678 that has greater longevity. At the same time, BrC-MAC365 decreased by a factor of 3 from the Indo-Gangetic Plain (IGP) exit to the equatorial Indian Ocean, likely due to photochemical bleaching of organic chromophores. The high chlorine-to-sodium ratio at the BCOB, located near the source region, suggests a significant contribution of chorine from anthropogenic activities. Particulate Cl− has the potential to be converted into Cl radicals, which can affect the oxidation capacity of polluted air. Moreover, Cl− is shown to be nearly fully consumed during long-range transport. The results of this synoptic study, conducted on a large southern Asian scale, provide rare observational constraints on the optical properties of ambient BC (and BrC) aerosols over regional scales, away from emission sources. They also contribute significantly to understanding the aging effect of the optical and chemical properties of aerosols as pollution from the Indo-Gangetic Plain disperses over the tropical ocean.
Multi-scale soil moisture data and process-based modeling reveal the importance of lateral groundwater flow in a subarctic catchment
Authors: Nousu Jari-Pekka , Leppä Kersti , Marttila Hannu , Ala-aho Pertti , Mazzotti Giulia , Manninen Terhikki , Korkiakoski Mika , Aurela Mika , Lohila Annalea , Launiainen Samuli
Published: October 2024

Abstract. Soil moisture plays a key role in soil nutrient and carbon cycling; plant productivity; and energy, water, and greenhouse gas exchanges between the land and the atmosphere. The knowledge on drivers of spatiotemporal soil moisture dynamics in subarctic landscapes is limited. In this study, we used the Spatial Forest Hydrology (SpaFHy) model, in situ soil moisture data, and Sentinel-1 synthetic aperture radar (SAR)-based soil moisture estimates to explore spatiotemporal controls of soil moisture in a subarctic headwater catchment in northwestern Finland. The role of groundwater dynamics and lateral flow in soil moisture was studied through three groundwater model conceptualizations: (i) omission of groundwater storage and lateral flow, (ii) conceptual TOPMODEL approach based on topographic wetness index, and (iii) explicit 2D lateral groundwater flow. The model simulations were compared against continuous point soil moisture measurements, distributed manual measurements, and novel SAR-based soil moisture estimates available at high spatial and temporal resolutions. Based on model scenarios and model–data comparisons, we assessed when and where the lateral groundwater flow shapes shallow soil moisture and under which conditions soil moisture variability is driven more by local ecohydrology, i.e., the balance of infiltration, drainage, and evapotranspiration. The choice of groundwater flow model was shown to have a strong impact on modeled soil moisture dynamics within the catchment. All model conceptualizations captured the observed soil moisture dynamics in the upland forests, but accounting for the lateral groundwater flow was necessary to reproduce the saturated conditions common in the peatlands and occasionally in lowland forest grid cells. We further highlight the potential of integrating multi-scale observations with land surface and hydrological models. The results have implications for ecohydrological and biogeochemical processes, as well as for modeling hydrology and Earth system feedbacks in subarctic and boreal environments.
Rapid simulation of wave runup on morphologically diverse, reef-lined coasts with the BEWARE-2 (Broad-range Estimator of Wave Attack in Reef Environments) meta-process model
Authors: McCall Robert , Storlazzi Curt , Roelvink Floortje , Pearson Stuart G. , de Goede Roel , Antolínez José A. Á.
Published: October 2024

Abstract. Low-lying, tropical, coral-reef-lined coastlines are becoming increasingly vulnerable to wave-driven flooding due to population growth, coral reef degradation, and sea-level rise. Early-warning systems (EWSs) are needed to enable coastal authorities to issue timely alerts and coordinate preparedness and evacuation measures for their coastal communities. At longer timescales, risk management and adaptation planning require robust assessments of future flooding hazard considering uncertainties. However, due to diversity in reef morphologies and complex reef hydrodynamics compared to sandy shorelines, there have been no robust analytical solutions for wave runup to allow for the development of large-scale coastal wave-driven flooding EWSs and risk assessment frameworks for reef-lined coasts. To address the need for fast, robust predictions of runup that account for the natural variability in coral reef morphologies, we constructed the BEWARE-2 (Broad-range Estimator of Wave Attack in Reef Environments) meta-process modeling system. We developed this meta-process model using a training dataset of hydrodynamics and wave runup computed by the XBeach Non-Hydrostatic process-based hydrodynamic model for 440 combinations of water level, wave height, and wave period with 195 representative reef profiles that encompass the natural diversity in real-world fringing coral reef systems. Through this innovation, BEWARE-2 can be applied in a larger range of coastal settings than meta-models that rely on a parametric description of the coral reef geometry. In the validation stage, the BEWARE-2 modeling system produced runup results that had a relative root mean square error of 13 % and relative bias of 5 % relative to runup simulated by XBeach Non-Hydrostatic for a large range of oceanographic forcing conditions and for diverse reef morphologies (root mean square error and bias 0.63 and 0.26 m, respectively, relative to mean simulated wave runup of 4.85 m). Incorporating parametric modifications in the modeling system to account for variations in reef roughness and beach slope allows for systematic errors (relative bias) in BEWARE-2 predictions to be reduced by a factor of 1.5–6.5 for relatively coarse or smooth reefs and mild or steep beach slopes. This prediction provided by the BEWARE-2 modeling system is faster by 4–5 orders of magnitude than the full, process-based hydrodynamic model and could therefore be integrated into large-scale EWSs for tropical, reef-lined coasts and used for large-scale flood risk assessments.
MAESSTRO: Masked Autoencoders for Sea Surface Temperature Reconstruction under Occlusion
Authors: Goh Edwin , Yepremyan Alice , Wang Jinbo , Wilson Brian
Published: October 2024

Abstract. This study investigates the use of a masked autoencoder (MAE) to address the challenge of filling gaps in high-resolution (1 km) sea surface temperature (SST) fields caused by cloud cover, which often result in gaps in the SST data and/or blurry imagery in blended SST products. Our study demonstrates that MAE, a deep learning model, can efficiently learn the anisotropic nature of small-scale ocean fronts from numerical simulations and reconstruct the artificially masked SST images. The MAE model is trained and evaluated on synthetic SST fields and tested on real satellite SST data from the Visible Infrared Imaging Radiometer Suite (VIIRS) sensor on the Suomi NPP satellite. We demonstrate that the MAE model trained on numerical simulations can provide a computationally efficient alternative for filling gaps in satellite SST. MAE can reconstruct randomly occluded images with a root mean square error (RMSE) of under 0.2 °C for masking ratios of up to 80 %. A trained MAE model in inference mode is exceptionally efficient, requiring 3 orders of magnitude (approximately 5000×) less time compared to the conventional approaches of cubic radial basis interpolation and Kriging tested on a single CPU. The ability to reconstruct high-resolution SST fields under cloud cover has important implications for understanding and predicting global and regional climates and detecting small-scale SST fronts that play a crucial role in the exchange of heat, carbon, and nutrients between the ocean surface and deeper layers. Our findings highlight the potential of deep learning models such as MAE to improve the accuracy and resolution of SST data at kilometer scales. This presents a promising avenue for future research in the field of small-scale ocean remote sensing analyses.
The importance of diabatic processes for the dynamics of synoptic-scale extratropical weather systems – a review
Authors: Wernli Heini , Gray Suzanne L.
Published: October 2024

Abstract. Many fundamental concepts of synoptic-scale extratropical dynamics are based on the quasi-geostrophic equations of a dry atmosphere. This “dry dynamics” provides the essential understanding of, for example, the formation of extratropical cyclones and the propagation of Rossby waves and makes potential vorticity (PV) a materially conserved quantity. Classically, for extratropical weather systems, the importance of so-called “diabatic effects”, e.g. surface fluxes, phase changes of water in clouds, and radiation, has been regarded as secondary compared to the dry dynamical processes. As outlined in this review article, research during recent decades has modified this view of the role of diabatic processes. A combination of complementary research approaches revealed that the nonlinear dynamics of extratropical cyclones and upper-tropospheric Rossby waves is affected – in some cases strongly – by diabatic processes. Despite the violation of material PV conservation in the presence of diabatic processes, the concept of PV has been of utmost importance to identify and quantify the role of diabatic processes and to integrate their effects into the classical understanding based on dry dynamics. This review first summarises the theoretical concepts of diabatic PV modification, moist PV, and slantwise moist convection and provides a concise overview of early research on diabatic effects until the late 1970s. Two poorly predicted high-impact cyclones affecting eastern North America then triggered an impressive diversity of efforts to investigate the role of diabatic processes in rapid cyclone intensification in the last 2 decades of the 20th century. These research activities, including the development of sophisticated diagnostics, growing applications of the Lagrangian perspective, real-case and idealised numerical experiments, and dedicated field experiments, are reviewed in detail. This historical perspective provides insight about how societal relevance, international collaboration, technical development, and creative science contributed to establishing this important theme of dynamical meteorology. The second part of the review then more selectively outlines important achievements in the last 2 decades in our understanding of how diabatic effects, in particular those related to cloud microphysics, affect the structure, dynamics, and predictability of different types of extratropical cyclones and their mesoscale substructures, upper-tropospheric blocks, Rossby waves, and interactions. A novel aspect is the relevance of research on diabatic processes for climate change research. The review closes by highlighting important implications of investigating diabatic processes in extratropical weather systems for the broader field of weather and climate dynamics and its fundamentals and representation in numerical models.
МОДЕЛИРОВАНИЕ ИЗНАШИВАНИЯ ЛОПАСТНЫХ НАСОСОВ
Authors: А.Ю. Албагачиев , Н.И. Смирнов
Published: October 2024

Приведены результаты расчетно-экспериментальных исследований моделирования лопастных насосов. Получено распределение износа радиальных сопряжений и виброскорости по длине насосной секции и предполагаемая форма упругой линии вала. Предложены: кинетическое уравнение абразивного износа, уравнение расхода через зазор, и уравнение скорости износа.

The results of computational and experimental studies of modeling vane pumps are presented. The distribution of wear of radial joints and vibration velocity along the length of the NS and the expected shape of the elastic line of the shaft were obtained. The following are proposed: the kinetic equation of abrasive wear, the equation of flow through the gap, and the equation of wear rate.
ДИНАМИЧЕСКОЕ УПРАВЛЕНИЕ РЕЗОНАНСНОЙ ЧАСТОТОЙ ПОЛОТНА ПИЛЬНОГО МОДУЛЯ, СОВЕРШАЮЩЕГО КРУГОВОЕ ПЛОСКОЕ ВРАЩАТЕЛЬНО-ПОСТУПАТЕЛЬНОЕ ДВИЖЕНИЕ
Authors: М.А. Блохин , И.И. Дымчаков , А.П. Шеин , Д.Д. Емельянов
Published: October 2024

Статья посвящена проектированию и инженерному расчету динамической устойчивости пильного полотна распиловочного оборудования нового вида с пильным модулем, совершающем круговое плоское вращательно-поступательное движение. Представленное оборудование относится к области распиловки твердых материалов, преимущественно древесины, но также и металла, пластмасс, камня, кости, стекла и других. Главным сборочным узлом оборудования является пильный блок, состоящий из шести пильных модулей, обеспечивающих его динамическое равновесие без дополнительных балансировочных (корректирующих) элементов.

The article is devoted to the design and engineering calculation of the dynamic stability of the saw blade of a new type of sawing equipment with a saw module performing a circular plane rotational and translational motion. The presented equipment relates to the field of sawing solid materials, mainly wood, but also metal, plastics, stone, bone, glass and others. The main assembly unit of the equipment is a saw block consisting of six saw modules that ensure its dynamic equilibrium without additional balancing (corrective) elements.
АНАЛИЗ СОВРЕМЕННЫХ ШИРОКО РАСПРОСТРАНЕННЫХ СИСТЕМ ЧПУ
Authors: А.А. Фролов , Л.В. Шипулин
Published: October 2024

Современное машиностроение активно развивается и вместе с этим повышается цифровизация производств. Проведенное исследование показывает особенности и различия распространенных на территории РФ систем ЧПУ: Fanuc, Sinumerik и Балт-систем. Рассмотрены основные функции и дополнительные возможности каждой из систем, а также описаны их возможные модификации, в зависимости от типа кинематики оборудования и направления производства.

Modern machine building is actively developing and along with it the digitalization of production is increasing. The conducted research shows the features and differences of CNC systems widespread in the territory of the Russian Federation: Fanuc, Sinumerik and Balt-systems. The main functions and additional possibilities of each system are considered, and also their possible modifications are described, depending on the type of equipment kinematics and production direction.
Medicinal Plants Mediated Metal-Based Nanoparticles for Biomedical Applications and Environmental Remediation: A Review
Authors: Saleem Tahira , Tareen Muhammad Humble khalid , Mehmood Wasif , Muhammad Rashid  , Ayesha Ahmed Sumra
Published: October 2024

Nanotechnology has emerged as one of the most popular multidisciplinary topics, with applications in a wide range of fields. Despite the use of numerous nanoparticle synthesis processes such as laser ablation, mechanical milling, spinning, and chemical deposition, the process is unsuitable for continuous production due to the use of dangerous chemicals and the high cost. As a result, the need for a long-term, cost-effective, and environmentally responsible growth strategy has grown in recent years. Green synthesis is gaining huge interest as a dependable, long-lasting, and environment-friendly way to synthesize a variety of nanoparticles, different secondary metabolites including polyphenols, flavonoids, and terpenoids present in plant extract act as reducing agents for the synthesis of nanoparticles. Despite several reports on the biological activities (antimicrobial, antioxidant, cytotoxic, catalytic, etc.), only a handful of studies have compared these activities with their chemically synthesized counterparts. The mechanism for the biosynthesis of metal nanoparticles by Mulberry and Ficus benghalensis extracts and their characterization using analytical techniques. Additionally, applications of these metal nanoparticles like therapeutic uses, industrial catalysts, and environmental remediations are highlighted.
Synthesis and Characterization of Barley Starch-g-Polyacrylamide with Zinc Sulphate (ZnSO4) Metal Salt
Authors: Sidra Ghafoor  , Fakiha Nazakat  , Moonsa Haq  , Fatima Choudry  , Rimsha Kiran  , Shaneeza Tariq  , Aatika Naveed  , Abbas Nasir , Ihsan Ali  , Noor Hassan
Published: October 2024

There has been extensive interest from researchers in utilizing the natural biopolymer as a reinforcement material in thermoplastic composite. Growing research has been carried out on natural biopolymer reinforcement thermoplastic composites due to their low processing cost. Starch, a natural carbohydrate biopolymer due to its biodegradability and versatility, has become a subject of industrial and academic studies for many decades. Grafting of starch on various monomers increased the hydrophilicity and hydrophobicity. High viscosity, thermal stability, biodegradability, good film-forming properties, and water absorption capacity are some properties shown by the graft co-polymerization of starch. The present work was conducted to synthesize the barley starch-g-polyacrylamide-based composite material. In this research the effect of different weight percentages of metal (?10%) on different properties of starch-g- polyacrylamide (20% and 80%) composite was studied. The analytical techniques including Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (X-ray), and scanning electron microscope (SEM) were used for the characterization of composite material. The composition of the synthesized composite was assessed by FTIR which confirmsthe functionalization of the prepared composite and there is a strong interaction between composite and metal due to coordinate covalent bonds. XRD defines the crystalline structure of the composite the morphological changes were studied by SEM.
Foreign Direct Investment and Income Inequality Nexus in Middle-Income Countries: Exploring the Role of Research and Development Expenditure
Authors: Muhammad Adnan Yasin  , Madiha Hasan  , Robina Anwar
Published: October 2024

The study explored the role of Research and Development Expenditure in determining the linkages between foreign direct investment (FDI) and income inequality within middle-income countries. World development indicators were used as a source for panel secondary data from 1990-2023. Panel unit root analysis was employed for data stationarity. The Panel co-integration analysis using the Fully Modified Ordinary Least Square (FMOLS) technique was applied to obtain correlations among three core variables. The findings explain that co-integration exists between variables; all variables are stationary at the first difference level. The FMOLS model incorporates the impact of FDI on the income inequality index with control variables. The analysis suggests that FDI in middle-income countries may decrease income inequality. Increasing research and development expenditures can reduce income inequality by promoting innovation and reducing reliance on external funding.
Perspectives Regarding the Menstrual Cup
Authors: Prince Lija , V. Kumar Anu.
Published: October 2024

A menstrual cup, which keeps the vagina clean during the monthly cycle, is inserted into the vagina. Menstruation cups are often made of flexible medical-grade silicone, thermoplastic isomers, or latex. They resemble bells and have stems or rings on them. The bell-shaped cup is used for both insertion and removal, pressing on the vaginal wall just below the cervix to hold menstrual fluids in place. It is inexpensive, eco-friendly, and simple to use.
The algorithm of political socialization of youth people in the virtual space
Authors:   Lipetsk State Technical University, Gorodova Jessica D. , Pachin Georgy R. ,   Lipetsk State Technical University, Kasenov Askar D. ,   Lipetsk State Technical University
Published: October 2024

: This article is devoted to the formation of an algorithm for the political socialization of young people in the virtual space. The theoretical analysis of the basic concepts is carried out: “political socialization”, “Internet”, “Internet technologies”, “virtual space”. The article analyzes the subject of acmeology, the acmeological approach to the political socialization of youth. The algorithm of political socialization in the virtual space is formulated.
Acmeological approach to modernization processes in the education system
Authors:   Lipetsk State Technical University, Fedotov Aleksandr R. , Nabokov Leonid V. ,   Lipetsk State Technical University, Goncharova Valeria A. ,   Voronezh State University, Pachin Alexander R. ,   Lipetsk State Technical University
Published: October 2024

This study is devoted to the acmeological approach to the modernization processes that take place in the education system of the Russian Federation. The concept of acmeology is studied, the concept of modernization is indicated in the context of the modernization of legal education, and the acmeological approach to modernization is investigated.
Professor’s professional creed Kuzmina Nina Vasilievna - be а teacher of teachers and psychologists
Authors:   Vladimir State University named after Alexander and Nikolai Stoletovs, Zobkov Valery A.
Published: October 2024

Autobiographical data are given that explain her indefatigable thirst for knowledge. The life of а scientist is shown in dates, in changing jobs, which enriched her professional and scientific experience, which she frankly shared. Emphasis is placed on the fact that the summit spirit of the mountains is peculiar to her and she climbed the Mountain, called “acmeology”.
Nina Vasilyevna Kuzmina is an outstanding Acmeologist, Teacher, educator, patriot of Russian science
Authors:   Коstroma State University, Rumyantseva Zoya V.
Published: October 2024

This article characterizes the versatile qualities of the personality of the outstanding scientist Nina Vasilievna Kuzmina, one of the associates of B.G. Ananiev in substantiation and development of acmeological science as a potential source of progressive development of modern Russian society. Nina Vasilievna is an innovator scientist, educator, Teacher, who brought up a galaxy of acmeologists, a fighter for the approval of acmeological knowledge and a patriot of Russian science.
Evaluation of the effect of head rotation on face mask ventilation in adults under general anesthesia: A randomized, single-blind, crossover study
Authors: Kumar Prashant , Bhalotra Anju R. , Singh Rahil
Published: October 2024

Purpose: Effective face mask ventilation is a life-saving skill. Loss of muscle tone under general anesthesia may lead to tongue fall and pharyngeal collapse and reduce the efficiency of face mask ventilation. It has been suggested that lateral head rotation may improve the efficiency of face mask ventilation. The aim of this study was to compare face mask ventilation in neutral and head-rotated positions in adult patients under general anesthesia.

Methods: This randomized crossover study was conducted on 42 patients of both genders, aged 18–60 years, who were randomly assigned to group NRN (face mask ventilation performed in neutral–rotated–neutral head positions for one minute each) and group RNR (face mask ventilation performed in rotated–neutral–rotated head positions for one minute each). The primary outcome was the expired tidal volume (VTE) measured in both head positions during pressure control mode of ventilation with a peak inspiratory pressure of 15 cmH2O. Secondary outcomes included the number of patients with airway obstruction or low VTE during mask ventilation and the effects of age, height, Mallampati class, and airway obstruction or low VTE on VTE in the head-rotated position.

Results: The mean VTE was significantly higher in the neutral position (637.93 ± 186.62 ml) compared to the head-rotated position (625.30 ± 183.52 ml) (p = 0.036). The VTE was comparable in group NRN and group RNR in neutral (p = 0.455) and head-rotated positions (p = 0.464). The incidence of airway obstruction was similar in both positions and no patient had low VTE during mask ventilation. Age, height, Mallampati class, and airway obstruction or low VTE in neutral position had no effect on VTE in the head-rotated position.

Conclusion: There was a significant decrease in the VTE in the rotated head position compared to the neutral head position during mask ventilation in patients under general anesthesia.
Integration Of Yoga In Higher Education For Regular, Online And Distance Modes Of Learning
Authors: Rana Dr. Laxmikanta
Published: October 2024

Purpose: This article explores the efficacy of yoga in the education system and the importance of integrating yoga into higher education. It highlights the important aspects of yogic practices especially suitable for higher education students and designs an integrated yoga protocol for their daily practices towards physical and mental wellbeing. The study emphasizes that the integration of yoga in higher education should not be restricted to regular mode students alone but can be imparted to online and distance mode learners as well. Design/methodology/approach: This article employs a theoretical general review outlook on available related literature to explore the integration of yoga in higher education irrespective of all modes of learners. Findings: The study reveals that integrating yoga into higher education is essential and should be prioritized to enhance students' physical and mental wellbeing, potentially improving academic performance in corresponding to study stress and overall outcomes. The study concludes that yoga should be made compulsory in higher education and equally available to all students, regardless of their mode of learning (regular, online, open, or distance). Practical implications: The study recommends incorporating physical aspects of yogic practices in school and intermediate levels, while emphasizing physical, mental, intellectual, and emotional aspects in higher education. Originality/value: This article serves as a threshold for recent valid and authentic research on yoga and education, highlighting yoga as an essential tool to be implemented in higher education systems, thereby maintaining and enhancing the quality of education.
Raman spectroscopy applied to the study of human red blood cells
Authors: Monção Mauricio Mitsuo , Do Nascimento Carina Soares , Dourado Raisa Cavalcante , De Araújo Roberto Paulo Correia
Published: October 2024

Raman spectroscopy is an analytical technique capable of providing detailed information about the molecular structure of biological tissues and fluids. Therefore, this article presents a review of Raman spectroscopy applied in studies with human red blood cells in order to synthesize information about the technological aspects and the Raman spectral characteristics identified by different studies. To this end, a search for articles was carried out in the PubMed, LILACS, SciELO and Cochrane databases, using pre-established descriptors, in the search for articles in Portuguese and English, published in the last ten years and available in full. Literature review articles, studies with whole blood, studies with animal red blood cells, and all those that deviate from the scope of the study are excluded. The results demonstrate that different technologies coupled to the Raman system and different technical ranges are used in the analysis of red blood cells. The discussion presents general aspects of the technique and the Raman spectral characteristics of healthy red blood cells and those altered as a result of diseases and other causes. Raman spectroscopy is versatile and widely used in investigations that require evidence at the molecular level of red blood cells.
A mathematical model describing the tip-stalk regulation in angiogenesis
Authors: Nascimento Dandara Lorrayne do , Alves Ana Paula , Calazans Leonardo  Ferreira , Agero Ubirajara , Atman Allbens P. F.
Published: October 2024

Angiogenesis is the process of new blood vessel growth from existing vessels, involving extensive cell signaling. Under normal conditions, new vessels are robust and organized, with a balance among angiogenesis factors. In abnormal conditions, such as tumor development, vessels are stunted and tangled due to an imbalance of these factors. Pathological angiogenesis stimulates rapid vessel growth to feed the oxygen and nutriente starved tumor. Inhibiting angiogenesis can cause side effects like hypertension, thrombosis, and fatigue. To better understand this process, significant effort has gone into studying signaling pathways, contributing to drug development for diseases like cancer. This study presents a mathematical model describing angiogenesis on a microscopic scale, comparing its results with experimental data on vascular network topology. The model, implemented in MatLab®, uses ordinary differential equations to represent cell behavior. Results show that altering VEGF (Vascular Endothelial Growth Factor) disrupts system balance, impacting angiogenesis and possibly explaining differences in network topology seen experimentally.
Educational intervention as a tool for raising awareness about rabies control among high school students in public institutions in Imperatriz, MA
Authors: Cruz Danny Hellen Guimarães , Sousa Helena Maria Vieira , Santos Josiel Cirqueira dos , Teixeira Lilyan da Silva , Arruda Amanda Jansen , Muniz Vitória Erlym Dias , Siqueira Rafaela Silva , Carvalho Amanda Mikaelly Marinho Lima , Viana Levi Guedes Setubal , Françoso Rafael
Published: October 2024

Rabies is classified as an acute and fatal zoonosis, transmitted to humans through the rabies virus presentin the saliva of infected mammals, primarily through bites, licks, or scratches. The main clinical signsinclude paralysis, behavioral changes, and excessive salivation. In urban areas, dogs and cats are theprimary transmitters, while bats predominate in rural zones. From 2014 to 2022, the state of Maranhãorecorded 62 outbreaks of the disease, primarily affecting cattle, dogs, horses, and cats. Although theSouthwest region of Maranhão, including the municipality of Imperatriz, currently shows no cases of rabies,prevention is crucial since the region is favorable for the occurrence of the disease, and no treatment isavailable for animals, leading to their death; additionally, treatment for humans carries risks. This studyaims to raise awareness among high school students in public schools about rabies, highlighting theimportance of prevention and control, especially in areas susceptible to transmission. The methodologyincluded the selection of schools and the application of pre- and post-lecture questionnaires, conducted byveterinary medicine students from the State University of the Tocantina Region of Maranhão, whichaddressed relevant aspects of the disease in urban and rural contexts. The results demonstrated a significantimprovement in participants' knowledge: the correct identification of rabies as a viral disease increasedfrom 71.8% to 98.1%, and recognition of the measures to be taken in the case of suspected rabies in ananimal rose from 77.5% to 91.4%. Moreover, the belief in the existence of an effective treatment for animalsdecreased from 80.4% to 62.7%. These data highlight the effectiveness of health education in correctingmisconceptions and empowering the population to adopt preventive measures in combating the disease. Keywords: Zoonosis; Prevention; Health education; Students.
Digital health solutions: Improving administrative workflow in community health centers
Authors: Alharbi Muteb Saeed Saud , Alshammari Mubarak Awad , Alotaibi Bader Naif , Alanazi Mohammed Ayyat , Alsulaiman Abdullah Lbrahim , Almzairie Khalid Ali
Published: October 2024

Background: Digital health interventions leverage telecommunication and virtual technologies to extend healthcare services beyond traditional settings. With increasing demand for healthcare systems, the integration of digital solutions has gained prominence. Rheumatoid arthritis (RA) management often requires time-intensive hospital visits, which complicates care delivery. Aim: The study aimed to design and implement a digital health solution for home-based monitoring of RA progression and treatment outcomes, reducing the need for outpatient visits. Methods: A stakeholder-centric approach was employed between 2015-2017. Data collection methods included previously published articles, reviews, interviews, cultural probes, and participatory workshops. Feedback was continuously integrated to refine the system. Results: Stakeholders appreciated the potential of reduced clinic visits through home monitoring. However, concerns emerged about resource allocation and the impact on clinical workflows. Nurses and doctors expressed differing views on handling patient data and responsibilities, revealing both opportunities and challenges in implementing digital solutions. Conclusion: The study highlights the benefits of integrating digital health interventions, such as reducing travel time and enabling continuous monitoring for RA patients. However, successful implementation requires addressing concerns related to workflow changes, resource allocation, and patient demographics.
Farmacêuticos na telefarmácia para o autocuidado no diabetes: validação de um guia prático
Authors: Queiroz Reijane Mara Pinheiro , Souza Nívia Tavares Pessoa de , Romero Nirla Rodrigues , Sousa Italo Nunes Arrais de , Araújo Breno Queiroz de , Ponciano Ângela Maria de Souza , Cavaco Afonso Miguel , Fonteles Marta Maria de França
Published: October 2024

Garantir a oferta de serviços de saúde essenciais, assim como o acesso e a sua continuidade durante e após o enfrentamento de tragédias humanas, é um desafio. O presente trabalho objetivou apresentar o processo de validação de um guia com script, que foi desenvolvido num estudo piloto, no período da pandemia de covid 19. Trata-se de uma abordagem metodológica qualiquantitativa de validação de conteúdo de um guia para telefarmácia. A validação deu-se através do método Delphi; aplicaram-se duas rodadas, sendo a primeira, para esclarecer o objetivo do estudo, e a segunda para obter dados qualiquantitativos sobre o consenso dos juízes. Para avaliar a concordância dos itens, foram considerados três critérios: clareza de linguagem, pertinência prática e relevância teórica, que foram relacionados a uma escala do tipo Likert. Para a validade de conteúdo, utilizou-se o Índice de Validade de Conteúdo (IVC) e para o instrumento geral (S-IVC). A confiabilidade da distribuição da pontuação atribuída pelos juízes foi verificada pelo Coeficiente de Correlação Intraclasse (CCI) e seus intervalos de 95%. O resultado de S-IVC foi de 0,99 e não houve discordância significativa na pontuação atribuída pelos avaliadores, sendo esta classificada como de excelente confiabilidade (CCI=0,989), atestada pelos seus intervalos de confiança (IC95%=0,979-0,996). Dessa feita, obteve-se, então, um guia com script para farmacêuticos utilizarem na telefarmácia, prontamente validado, conforme os resultados estatísticos apresentados, e disponível como estratégia para agregar valor aos serviços farmacêuticos prestados ao paciente com diabetes.
Declaration of Claims in International Insolvency Proceedings
Authors: Wilfinger Alexander
Published: October 2024

The ECJ ruled on a particularly controversial question in the recent case of Skarb Państwa/Riel: An action for declaration of the existence of claims for the purposes of their registration in the context of insolvency proceedings falls within the scope of the European Insolvency Regulation. This paper examines the implications of the decision with regard to jurisdiction, arbitration agreements and pending proceedings.
The Discovery of Mind. From Wundt to Neuroimaging
Authors: Roelofs Ardi
Published: October 2024

This book presents a concise history of the scientific discovery of the mind. Although people have speculated about the nature and functioning of their minds for thousands of years, it was only about 200 years ago that they replaced the philosophical armchair with the laboratory and began to investigate the mind scientifically. Surprisingly, the work of one of the founders of scientific psychology, Wilhelm Wundt (1832–1920), has been largely forgotten, despite its relevance to current psychology. Taking a fresh look at history, this book discusses important empirical and theoretical discoveries made in the few decades before and in the 150 years after the publication of Wundt’s groundbreaking monograph Grundzüge der physiologischen Psychologie in 1874. Crucial evidence from past behavioral and patient studies to recent neuroimaging is synthesized to support a thought-provoking account of key aspects of the human mind.
International Cooperation in Higher Education: Perspectives of Heads of International Cooperation from Cases of European Universities
Authors: Qi Zhengwen , Jing Meiying , Zhu Chang
Published: October 2024

Fostering international cooperation is essential for addressing global challenges. However, increasing uncertainties and polarisation necessitate a re-evaluation of the rationale and management of international cooperation among higher education institutions (HEIs). Recent research calls for greater attention to international cooperation beyond like-minded countries and emphasises the importance of understanding the perspectives of heads of international cooperation. This study addresses this theoretical gap by examining cooperation with Chinese universities from the perspectives of nine heads of international cooperation at six European universities.Utilising semi-structured interviews and reflexive thematic analysis, this study elucidates how these European universities establish and maintain cooperation with their Chinese counterparts. It clarifies the interactions among universities, governmental bodies, and policies, and identifies challenges encountered during cooperation. The findings contribute to the literature by offering practical insights and providing contextualised empirical data on future directions for international cooperation between European and Chinese HEIs. This study underscores the active and autonomous roles that universities should play in fostering international cooperation amid global uncertainties.
Karakter Janda Batak Hidup Dalam Lingkungan Heterogen Di Silencang Humbang Hasundutan Berdasarkan 1 Timotius 5:3-8
Authors: Flesia Nanda Uli Boangmanalu  , Lestari br. Silaban  , Anessa Mei Pasaribu  , Yubilate Chriswell Zebua
Published: October 2024

This article is based on the paradigm of lack of respect for women who are widows in society. Widows are considered weak individuals and unable to replace men's work in the household. But the reality is different for widows in Batak society. Widows in Batak society have a loyal character and have high hopes for their children. children as a means of restoring her widow status. The aim of this research is to get an answer to what extent the loyal character of Batak widows survives in a heterogeneous environment. The method used is descriptive qualitative, namely analyzing, comparing and concluding various opinions from source books/journals from various experts regarding the character of the loyal Batak widow. by exploring the characteristics of loyalty and courage of Batak widows, it contributes a positive paradigm towards women who have the status of widows in society, thereby providing a new perspective that better appreciates the role and contribution of widows in heterogeneous families and society.
Kristus sebagai Jembatan: Peran Kristus dalam Memediasi Perjumpaan dengan Allah
Authors: Yuwita Despriyantie  , Natalia Natalia  , Yohana Katerina Tinopi  , Sarmauli Sarmauli
Published: October 2024

Christ as the mediator between humans and God in Christian teachings, based on the Bible and Christian theology. The aim is to deepen understanding of Christ's role as mediator and its implications in the spiritual life of Christians. Biblical analysis methods are used to support the finding that Christ is the only way to God. The implications include strengthening spiritual connections, influencing the way Christians worship and pray, and deepening understanding of God's infinite love. This conclusion leads to an understanding that Christ as an intermediary strengthens faith and steadfastness in living daily life, as well as bringing comfort and hope to His people in facing life's challenges. This provides a foundation for further research in understanding the concept of Christ as mediator and its implications in religious practice and interreligious dialogue.
PERANAN WANITA KRISTEN BERDASARKAN AMSAL 31:10-31 TERHADAP MASA DEPAN KELUARGA GPIA CIBINONG
Authors: Joyce Linda , Windarti Maria Titik , Yuliani Yuliani
Published: October 2024

Permasalahan dalam penelitian ini adalah mengenai bagaimana peranan wanita Kristen terhadap masa depan keluarga yang berhasil. Pertama, dalam sebuah keluarga, wanita memiliki peranan yang sangat penting. Wanita bertanggung jawab atas banyak hal, termasuk mengurus rumah, mendidik anak, menyediakan makanan sehat, dan tugas-tugas lain yang krusial bagi kesejahteraan keluarga. Kedua, masa depan keluarga adalah kondisi keluarga di masa mendatang yang sangat dipengaruhi oleh tindakan dan keputusan yang diambil saat ini. Oleh karena itu, peranan wanita dalam keluarga sangat menentukan bagaimana keadaan keluarga tersebut di masa depan. Ketiga, peranan wanita Kristen terhadap masa depan keluarga sangat erat kaitannya dengan nilai-nilai yang diajarkan dalam Alkitab. Wanita Kristen yang menjalankan perannya sesuai dengan Firman Tuhan dalam Amsal 31:10-31 dapat membawa masa depan keluarga yang indah dan berhasil dalam Tuhan. Penelitian ini bertujuan untuk menguraikan bagaimana peranan wanita Kristen, berdasarkan Amsal 31:10-31, mempengaruhi masa depan keluarga. Strategi yang digunakan adalah metode kuantitatif dengan pengumpulan data melalui angket yang disebarkan kepada 13 responden. Angket tersebut berisi 24 butir pernyataan yang mengukur variabel Peranan Wanita (X) dan Masa Depan Keluarga (Y). Hasil penelitian menunjukkan bahwa terdapat pengaruh yang signifikan antara variabel X dan variabel Y, dengan r hitung sebesar 0,310 yang lebih besar dari r tabel sebesar 0,265 pada taraf signifikan 0,05. Peranan wanita Kristen berdasarkan Amsal 31:10-31 terbukti memberikan dampak positif terhadap masa depan keluarga jemaat di GPIA Cibinong. Wanita Kristen yang baik, cakap, dan takut akan Tuhan, yang menjalankan setiap tindakan sesuai dengan perintah Tuhan, mampu membawa keluarganya menuju masa depan yang berbahagia dan berhasil. Hasil penelitian ini menegaskan pentingnya peranan wanita Kristen dalam membentuk masa depan keluarga yang sukses dan diberkati.
Implementasi belajar Alkitab berdasarkan 2 Timotius 3:15 pada Pertumbuhan Kerohanian Anak di Antioch Mission Church Tangerang
Authors: Pora Apliana Lali , Dewi Ester Yunita , Telaumbanua Elianus
Published: October 2024

Anak-anak adalah anugerah terindah dari Tuhan yang harus dididik, dibina dan diajar sejak kecil. Didikan sejak kecil akan menjadi fondasi yang kuat bagi anak-anak dalam menjalani hidup mereka. Penelitian ini bertujuan untuk menguraikan bagaiman impelementasi belajar Alkitab pada anak berdasarkan 2 Timotius 3:15 dan menguraikan bagaimana kitab 2 Timotius 3:15 menjadi dasar bagi pertumbuhan kerohanian anak di Gereja Antioch Mission Church Tangerang. Adapun permasalahan dalam penelitian ini, melliputi kurangnya waktu anak dalam belajar Alkitab, kurangnya pemahaman dan pengetahuan anak tentang Firman Tuhan, serta pengaruh media sosial dan teknologi yang menjadi penghambat bagi anak-anak dalam membangun kerohanian mereka.
Penelitian ini menggunakan metode kualitatif dengan pengumpulan data melalui observasi, wawancara, studi dokumen, dan studi Pustaka. Dari hasil penelitian menunjukkan bahwa Implementasi belajar Alkitab pada anak sangat berdampak bagi pertumbuhan kerohani anak di Gereja Antioch Mission Church Tangerang. Melalui belajar Alkitab sejak dini, membantu anak-anak mengenal Tuhan Yesus Kristus, mampu memberikan mereka hikmat dan menuntun mereka kepada keselamatan oleh iman dalam Yesus Kristus. Untuk mengajarkan Alkitab pada anak, orang tua, guru sekolah minggu, dan gereja sangat berperang penting dalam membimbing, membina dan membentuk anak-anak untuk bertumbuh dalam pengenalan akan Tuhan Yesus Kristus dengan benar.
Mengokohkan Kemandirian Desa: Pelatihan Peningkatan Kapasitas Aparatur Pemerintahan Desa
Authors: Olis Olis
Published: October 2024

Village governance plays a central role in managing local affairs at the rural level, encompassing administration, infrastructure development, basic services, and community empowerment. This research focuses on capacity-building training for the officials of Sukajadi Village government to strengthen their administrative functions. Through a Pancasila-based approach, this training aims to enhance the understanding and skills of officials in carrying out administrative tasks effectively. The training methodology involves program development, training sessions using presentation methods and interactive discussions, and evaluations to improve the quality of activities. It is hoped that this training will assist the officials of Sukajadi Village government in providing better services to the community and strengthening village administration management, in line with the vision of inclusive and sustainable development