bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on the Construction Status of the Beijing-Tianjin-Hebei Medical Talent Community and the Countermeasures for Its Realization
Authors: Jing Chao , Zhang Jiaqi
Published: March 2024

In April 2015, the Political Bureau of the CPC Central Committee adopted the “Outline of the Plan for the Coordinated Development of Beijing, Tianjin, and Hebei.” In July 2017, the “Plan for the Integrated Development of Beijing, Tianjin, and Hebei Talents (2017–2030),” jointly prepared by the leading groups of the three regions, was officially released. The core of the coordinated development of these three regions is the orderly removal of non-capital functions from Beijing. Talents, especially medical talents, are integral to this transition. The construction of a medical talent community across these three regions promotes the further development of a healthier China, meets the growing needs of the people for a better life, and embodies the concept of putting people first. This paper begins by examining the current situation of the construction of the Beijing-Tianjin-Hebei medical talent community, reviewing the progress made, analyzing existing problems, and proposing targeted countermeasures and suggestions.
Mediating Effect of Self-Efficacy in Pain Management between Knowledge and Attitude of Pain toward Pain Management Practice among Nurses in Indonesia
Authors: Susanto Herry , Lee Tzu-Ying
Published: March 2024

Nurses' knowledge and attitudes significantly influence pain management practices. Higher levels of self-efficacy in pain management are associated with improved pain. This study explored the relationships between nurses’ knowledge and attitudes toward pain, self-efficacy in pain management, and actual pain management practices. This study employed a cross-sectional study which conducted at Sultan Agung Islamic Hospital, Indonesia, involving 249 nurses selected based on predefined criteria. Participants responded to an online survey encompassing demographic queries and standardized tools, namely the Knowledge and Attitude Survey Regarding Pain (KASRP-IDN), the Pain Management Self-Efficacy Questionnaire (PMSEQ-IDN), and the Nurse Behavior Questionnaire in Pain Management (NBQ-P). Mediation analysis was further conducted using the PROCESS add-on to discern the mediating effect of self-efficacy in pain management between knowledge and attitude of pain toward pain management practice among nurses. The study showed significant positive relationships among Knowledge and Attitude Survey Regarding Pain (KASRP), Pain Management Self-Efficacy (PMSE), and Pain Management Practice. However, the mediation analysis depicted that self-efficacy exerted a relatively modest mediating effect between KASRP and pain management practice (K2=0.17, CI= 0.05-0.27). The findings manifest the positive associations between knowledge-attitude regarding pain, self-efficacy in pain management, and pain management practices among nurses. In the future, in-service programs related to pain management should increase the nurses’ knowledge and attitude and enhance their confidence, resulting in actual practice in pain management. However, the mediation effect of self-efficacy is modest, indicating the plausible existence of other contributory variables or factors warranting further exploration and elucidation.
ARTIKEL REVIEW, PEMANFAATAN TELUR IKAN SEBAGAI PRODUK KONSENTRAT PROTEIN IKAN
Authors: - Junianto
Published: March 2024

Limbah industri pengolahan hasil perikanan yang potensial untuk dimanfaatkan menjadi produk bernilai tambah tinggi adalah telur ikan.  Kandungan zat gizi telur ikan  tertinggi setelah air adalah protein, sehingga sangat cocok untuk dibuat produk konsentrat protein.  Artikel ini bertujuan untuk mereview pemanfaatan telur ikan menjadi produk konsentrat protein.  Metode penelitian yang digunakan adalah studi literatur tentang konsentrat protein yang berbahan baku telur ikan khususnya ikan komersial yang digunakan sebagai bahan baku industri pengolahan.  Pencarian literatur menggunakan mesin pencari google chrome.  Pembahasan dikonsentrasi pada komposisi proksimat telur ikan, pembuatan konsentrat protein dan komposisi proksimat konsentrat protein telur ikan.  Data yang diperoleh dianalisis secara diskriptif komperatiif.  Berdasarkan hasil review dapat dinyatakan bahwa telur ikan sebagai produk limbah industri pengolahan ikan dapat dibuat atau dimanfaatkan menjadi produk konsentrat protein.  Prinsip tahapan pembuatannya yaitu pengeluaran air dan lemak semaksimal mungkin dari telur  ikan.  Produk konsentrat protein telur ikan dapat diaplikasi untuk makanan pendamping air susu bayi (MP-ASI).
Evolution of an introductory undergraduate biology course through collaborative action research
Authors: Kazempour Mahsa , Amirshokoohi Aidin , Goudsouzian Lara
Published: March 2024

Over the past few decades, we have witnessed an increasing emphasis on the significance of restructuring and revolutionizing undergraduate science education in achieving the goal of preparing a scientifically literate population and safeguarding our democracy and the future of STEM workforce. This paper reports on a collaborative action research conducted to reform and modify an introductory undergraduate biology course taught by the third author with professional support and feedback provided by the other authors. The findings will be discussed in the form of a case study focusing on the initial features of the course, continual feedback and professional growth, modifications to the course, and future plans for further revising the course.
Association of two square difference identity to regular polygons and circles
Authors: Aslaner Recep , Ilhan Aziz
Published: March 2024

GeoGebra is a dynamic software that is frequently used and of increasing importance in mathematics teaching processes in our digital age. Accordingly, in this study a new perspective has been brought to the proofs of the “two square difference identity” expressed for the square, which is a flat polygon, made with different approaches. With side lengths a, b, and a>b, it has been shown that the identity given by the equation (difference of area) a2-b2=(a-b)(a+b) is true for other regular polygons as well. In the study, direct proof method was used within the framework of the principle of conservation of measure, which is one of the basic principles of geometry teaching. GeoGebra program, which is a dynamic geometry software, was preferred for drawing geometric shapes used in proofs. In order to generalize the number n, a different fragmentation technique was preferred to the proofs made using different drawings for equilateral triangle and square, which are the simplest regular polygons. It has also been shown that this identity is true for circles viewed as polygons with an infinite number of sides.
Digital Literacy: Fundamental Competence for Modern Society
Authors: Mujiono Mujiono
Published: March 2024

This research highlights the significance of digital literacy in our increasingly interconnected modern society through information technology. It addresses the primary challenges faced by modern society in managing information in the digital era, including the spread of fake news and data privacy breaches. The research aims to elucidate the contribution of digital literacy in addressing these challenges faced by modern society and identify its positive impacts in safeguarding data security, combating misinformation, and enabling active participation in the digital community. The research methodology employed a systematic literature review (SLR) to gather, evaluate, and synthesize literature related to modern society and digital literacy. The findings of the research reveal that digital literacy plays a pivotal role in assisting individuals in comprehending, filtering, and assessing information encountered online while safeguarding their privacy in the digital environment. In conclusion, digital literacy is not just a technical skill but also the key to responsibly and wisely harnessing digital opportunities.
iSpring on English Language Teaching and Learning: A Literature Review
Authors: Auliya Prativi Khilyatul
Published: March 2024

iSpring is one of various software which is benefit in English language teaching and learning. There are numerous researches that bring up the use of iSpring to support the material and quiz development. This research aims at providing comprehensive literature review about iSpring in English language teaching and learning. This research’s objectives are investigating; 1) the roles of iSpring in English language teaching and learning and 2) the effectiveness of iSpring in English language teaching and learning. Qualitative research method with library research approach was used in this research. The data consists of 3 theses, 4 conference proceedings, 5 journal articles that taken mostly from Google Scholar. The data then analysed using content analysis to match the objective of this research. The findings showed that iSpring has several important roles for English language teaching and learning such as; making English teaching and learning activities becomes easier; helping students to learn English language; creating interest, motivation, confident, concentration, and independence for students in English learning; supporting all types of learning styles and various level of students in English learning; providing effective English teaching and learning activities; and also accommodating various English teaching methods. Besides that, this research also showed that iSpring was effective for foreign language distance learning, improving students’ independence on self-evaluation, improving receptive skill, and productive skills as well. Therefore, iSpring is suitable to be used in education, especially to support the English language teaching and learning.
Zoom Cloud Meeting: Improving Elementary School Elementary School Students' Activity and Learning Outcomes
Authors: Hikmiah Alien Nisaul , Nugroho Arya Setya
Published: March 2024

This study was conducted to address the challenges of face-to-face meetings, which were found to often clash with elementary school students. Meanwhile, the use of technology by elementary school students is less effective even though they have tools that support internet learning. Therefore, based on these problems, the implementation of learning using Zoom application is expected to solve the problem of physical meeting. This study used Classroom Action Research (CAR) with the stages of planning, implementing, observing, and reflecting in each cycle. Furthermore, data were collected through observation and tests, using instruments in the form of elementary school students’ activity sheets and learning outcomes. The results showed the use of zoom cloud meetings improved elementary school students’ activity and learning outcomes. The activity value was 49.17 in cycle 1 and 68.3 in 2, which fulfills the success indicators of at least 65%. Also, the learning outcomes increased by 23.3% from 56.7% in cycle 1 and 80% in 2. Therefore, the Zoom application can be used for online learning, which is proven to increase the number of elementary school student attendance and their learning outcomes.
Performance of Google Translate, Microsoft Translator, and DeepL Translator: Error Analysis of Translation Result
Authors: Fitria Tira Nur
Published: March 2024

This research simulates the use of Google Translate and Microsoft Translator in translating Indonesian into English abstract and analyzes errors of translation results in the aspect of grammar and spelling using Grammarly Premium. This research is descriptive qualitative. The result analysis shows several writing issues (errors) of translation results using Microsoft Translator (MT), Google Translate (GT), and DeepL Translator (DT) in the aspect of clarity, correctness (correction), and delivery. First, there are  26 writing issues from MT including 1) 4 clarity (4 unclear sentences), 2) 21 correctness (2 comma misuse within clauses, 4 punctuation in compound/complex sentences, 5 wrong or missing prepositions, 3 incorrect verb forms, 2 determiner use, 2 conjunction use, 2 confusing words, 1 improper formatting), 3) 1 delivery (1 incomplete sentences). Second, there are 25 writing issues from GT including 1) 6 clarity (4 unclear sentences and 2 wordy sentences), 2) 17 correctness (1 misplaced word or phrase, 1 text inconsistencies, 1 comma misuse within clauses, 4 punctuation in compound/complex sentences, 3 wrong or missing prepositions, 3 incorrect verb forms, 2 conjunction use, 1 confusing word, and 1 determiner use.). 3) 2 delivery (2 incomplete sentences). Third, there are 10 writing issues from DT including 3 comma misuse within clauses, 1 incorrect noun number, 1 faulty subject-verb agreement, 1 wrong or missing preposition, 1 improper formatting, 1 misuse of modifiers, 1 conjunction use, and 1 confused word. Online translator including MT, GT, and DT may help in translating foreign language texts, but it does not always provide accurate translations. Thus, whether consciously or unconsciously, each translation machine contains its traits, whether directly or indirectly, human participation cannot be separated from machine translation technology. However, no computer translator can provide translations with the same precision as humans. It means that they are still a machine that is not able to match human capabilities equipped with feelings and thinking processes that describe them.
A Combination of Three Scales for Measuring User-Perceived Usability of a Clinical Information System: Which Approach Produces the Most Informative Results?
Authors: Rahmatizadeh Shahabedin , Kirakowski Jurek , Valizadeh-Haghi Saeideh , Taheri Maryam , Tavasoli Sanaz
Published: March 2024

Introduction: For the first time in Iran, a kidney stone clinical information system (CIS) has been designed to manage and calculate and visualize patients’ kidney stone risk profiles. Nevertheless, the usability of this system has not been evaluated yet. Medically, this study aims to evaluate the user-perceived usability of the kidney stone CIS. Technically, the current study aims to determine which user-perceived usability testing approach produces the most informative results about the usability of this system.Material and Methods: Three questionnaires, including system usability scale (SUS), software usability measurement inventory (SUMI), and post-study system usability questionnaire, were applied to carry out the study. A total of 15 users of the kidney stone CIS participated.Results: The findings revealed that the system is of medium usability. Moreover, of the three methods used, the SUMI echoes the comments of the end-users. Despite the medium usability of the system, it was comprehensive in terms of proper data collection and storage, as well as reporting. The interface design, the lack of appropriate guidance, the time-consuming data entry, and the slow reporting system were aspects needed improvement.Conclusion: Using a combination of tools is recommended for usability evaluation. Since there is much space in the Global and each sub-scale, whereby measures may improve with SUMI, this research recommends its use for future evaluation of the kidney stone CIS.
NATURAL DISASTER EVENT MAPPING IN WEST JAVA USING K-MEANS ALGORITM
Authors: Sagaino Sagaino , Mulyana Teady Matius Surya , Suryantara I Gusti Ngurah , Ginting Jusia Amanda , Adikara Fransiskus
Published: March 2024

 Natural disaster is an event that cannot be avoided, therefore a mapping of occurrence of the natural disaster is needed. In additional to mapping, clustering of natural disaster events is also needed to determine which areas have low to high intensity events. In performing the clustering, a method or algorithm can be used, namely the k-means algorithm.

In the research conducter, the scope of natural disasters is West Java Province with the attributes used are floods, landslides and tornadoes. And also from this research, it was conducted to find out how many optimal number of clusters that can be clustered.

The method that used  in this study is the K-Means algorithm which is used to perform clustering. The Elbow method is used to determine the optimal K value from the dataset by calculate the SSE (Sum Square Error) of each predetermined cluster.

From the result of its application, the K-Means algorithm can cluster datasets of Natural Disaster in West Java with predetermined attributes. Based on the calculation results from the elbow method, the value of K from the dataset is 4. And from the research conducter, the accuracy rate of each cluster is 0,04% to 0,56%.

Keywords:  K-Means, Natural Disaster, Elbow Method, Cluster, Machine Learning
Mejora de la competencia comunicativa, de indagación y digital a través del uso de las TIC en el aprendizaje de los fraseologismos en clase de ruso
Authors: Gorozhankina Tamara , Corral-Robles Silvia
Published: March 2024

La irrupción de las TIC en el panorama actual ha tenido una enorme repercusión en el ámbito de la educación en los últimos años, en concreto en la enseñanza de lenguas. Este enfoque de enseñanza digital ha cobrado impulso debido al hecho de que los estudiantes son los protagonistas de su propio proceso de aprendizaje. Este cambio implica una renovación del enfoque metodológico en la enseñanza de lenguas extranjeras. El presente estudio pretende ofrecer una visión general del impacto de la enseñanza de los fraseologismos en ruso como lengua extranjera a través del uso de las TIC en la adquisición de la competencia comunicativa, de indagación y digital de los participantes de la intervención llevada a cabo en el Centro Ruso. Para el análisis de los datos de dicha intervención, se diseñó un estudio cualitativo a través del uso del diario reflexivo como herramienta de recogida de datos para evaluar el logro de dichas competencias. Los resultados muestran que, aunque la enseñanza de los fraseologismos puede ser un reto para los estudiantes, favorece el desarrollo de diferentes subcompetencias comunicativas, la competencia de indagación y la competencia digital.
Recalificar el páramo. Bases para un nuevo modelo traductológico de análisis del texto teatral
Authors: L. Lapeña Alejandro
Published: March 2024

A pesar de que la traducción teatral tiene una larga tradición, su estudio es algo relativamente novedoso dentro de los Estudios de Traducción. No en vano, Santoyo calificó la situación en 1995 de «páramo». Hoy, cerca de 20 años después, las cosas han mejorado bastante, pero es cierto que sigue siendo una de las disciplinas menos estudiadas. En este artículo, estudiaremos las diferencias del texto teatral con respecto a otros tipos de textos literarios y sentaremos las bases de un nuevo modelo traductológico de análisis basado en la práctica y, más concretamente, en la traducción y posterior montaje de dos obras de teatro del dramaturgo portugués José Maria Vieira Mendes.
Paratraducción de la pareja texto/imagen: mutilación y manipulación de paratextos lingüísticos e icónicos
Authors: Méndez González Ramón
Published: March 2024

En la nueva era digital, textos y paratextos conviven en un entorno intertextual en el que las influencias de otros medios son constantes. Si texto e imagen conviven como una pareja indivisible, el traductor tendrá que saber trabajar con ambos códigos para conseguir la adaptación cultural necesaria para que el producto en cuestión funcione adecuadamente en un nuevo mercado. Esto es algo muy habitual en la traducción de cómic, aunque cada vez más está empezando a tener relevancia en la traducción audiovisual, aunque el traductor puede no tener a su disposición todos los medios necesarios para llevar a cabo una adaptación ideal en el que la fusión de texto e imagen cobren el mismo sentido en la versión traducida que en el texto original. En el presente estudio analizaremos la relación entre texto e imagen, así como las necesidades intertextuales de diversos productos audiovisuales, para posteriormente estudiar el caso concreto de la franquicia Scott Pilgrim.
Otra mirada a la traducción e interpretación durante el Protectorado español en Marruecos: Abdelaziz Mohammed-Hammadi Haddu
Authors: Arias Torres Juan Pablo
Published: March 2024

El Cuerpo de Interpretación de Árabe y Bereber constituyó la piedra angular de los servicios de traducción del Protectorado español en Marruecos. Creado en 1942, vino a sustituir al casi homónimo Servicio de Interpretación de Árabe y Bereber en el que en 1929 se habían integrado los traductores e intérpretes del Ejército y de la Carrera de Intérpretes en el Extranjero a las órdenes de la Alta Comisaría de España en el país norteafricano. Bajo esta diversidad de denominaciones, fruto de una dinámica colonial que progresaba desde la acción diplomática y la ocupación militar hacia una administración efectiva del territorio, se acogía en definitiva a un mismo grupo de profesionales, unidos en destinos y tareas comunes, y divididos en dos escalas: una superior o técnica, con especialización en tareas de traducción, y una auxiliar dedicada fundamentalmente a tareas de interpretación...
La posedición: hacia una definición competencial del perfil y una descripción multidimensional del fenómeno
Authors: Sánchez-Gijón Pilar
Published: March 2024

A pesar de que la traducción automática y la posedición (TA + PE) han entrado en el mundo de la traducción a través fundamentalmente de la traducción de documentación técnica, actualmente su uso puede llegar a generalizarse como ya pasó con el uso de las herramientas de traducción asistida por ordenador (TAO). Sin embargo, la concepción teórica del perfil del poseditor en términos de competencia, así como la concepción del poseditor con la que se trabaja en el entorno de la industria de la traducción, se circunscribe a la del editor de segmentos en la lengua meta obtenidos a través de TA. En este artículo se presenta una concepción de la PE más compleja, equiparable a la del traductor a excepción de la subcompetencia instrumental. Esta concepción se fundamenta a partir de una comparación de las tareas que proveedores de servicios de traducción en un contexto de traducción asistida vs. un contexto de TA + PE. Además, este artículo propone abandonar la concepción homogénea de la PE que habitualmente se presenta de forma teórica y propone abordar esta modalidad desde diferentes dimensiones.
Translation Challenges in the Localization of Web Applications
Authors: De la Cova Elena
Published: March 2024

This preliminary study aims at exploring the nature of challenges that translators face when they take on a localization project of a web application. Taking into account that localization is an activity constrained by time, process and economic resources, translators need to make use of their full skill set to overcome the various challenges imposed by the source text and the localization process itself. For the purpose of this study, an ad hoc monolingual English corpus composed of the user interface strings of web applications has been used. Since multiple types of challenges are found in a localization project of this nature, this paper focuses on those related to internationalization practices and to constraints imposed by the translation memory segmentation process. Although localization is a mature field and a great deal of guidelines and best practices is available for content creators and tool developers, as found in this qualitative study, localizers can still suffer the consequences of deficient internationalization practices and non-ergonomic translation tools.
Implementasi Sistem Penjaminan Mutu Internal dalam Meningkatkan Mutu Pendidikan di MIN 1 Rejang Lebong
Authors: Okta Ria Enes Utami , Kusen Kusen , Wanto Deri
Published: March 2024

ABSTRACTInternal quality assurance is carried out with reference to national educational standards in order to realize the educational goals of the country. Internal quality is currently used in basic and secondary education in addition to universities. This study aims to identify and explain the internal quality system cycle's implementation. Data collecting methods include observations, interviews, and documentary research. According to the findings of this study, Darul Farah Cihampelas Secondary School has implemented the following quality improvement activities in accordance with the stages of the SPMI cycle: first, a school self-evaluation based on the education quality report; second, quality improvement planning through the creation of a quality assurance committee and a re-analysis of the results of the school self-evaluation; third, implementation of quality improvement; and fourth. The evaluation of educational quality comes in second. Quality strategy for the fifth fiscal year, evaluation following quality improvement, and quality improvement results. Implementing internal quality assurance will have an influence on the development of more creative teaching methods, student and school performance, internal and external customer happiness, and the fulfillment of the eight National Education Standards.
BETA DAN RETURN SAHAM YANG TERDAFTAR DI PERUSAHAAN INDEKS LQ-45 DAN JII PADA BEI: MELALUI PENDEKATAN MODEL DATA PANEL
Authors: Wafiah Nur Umaima , Harlindah Harlindah
Published: March 2024

Penelitian ini bertujuan untuk mengetahui pengaruh terkait beta (risiko) dengan return saham melalui pendekatan model panel. Jenis penelitian yang digunakan dalam penelitian ini adlah penelitian deskriptif dengan pendekatan kuantitatif. Adapun sampel dalam penelitian ini terdiri dari 50 perusahaan yang terdaftar di Indeks LQ-45 dan Jakarta Indeks Islam (JII) pada Bursa Efek Indonesia (BEI) selama masa periode 2018-2022. Hasil analisis menunjukkan bahwa beta berpengaruh positif terhadap return saham. Hal ini mampu dijadikan tolak ukur bagi investor dalam berinvestasi dalam rangka memperoleh keuntungan yang optimal, begitu pula dengan resikonya yang berbanding lurus.
Can pre-service teachers learn about fake news by playing an augmented reality escape game?
Authors: Buchner Josef , Höfler Elke
Published: March 2024

Fake news is increasingly becoming a major problem for global social coexistence, for example by undermining trust in democracies. There is a consensus that educational institutions need to respond and prepare students to recognize fake news. Teachers have a central role to play in preparing students and therefore need to learn about fake news during their studies. Previous research has shown that games are particularly effective for learning about fake news, but the group of pre-service teachers has not yet been investigated. The aim of this study is to address this gap by examining whether pre-service teachers can learn about fake news using the augmented reality escape game Escape Fake. To investigate this question, a pre-/post-test design was conducted with 45 pre-service teachers (four males, mean age=22.59 years, standard deviation=1.80). The results show that after playing Escape Fake, the pre-service teachers demonstrate significantly higher knowledge about fake news, are significantly more critical towards online information, and are significantly more confident in being able to recognize fake news in the future. However, playing the game did not promote the ability to discern real from false information. The paper discusses reasons for this finding and suggests ways to improve learning with the game. Implications and future research needs are discussed.
Technological self-efficacy and mindfulness ability: Key drivers for effective online learning in higher education beyond the COVID-19 era
Authors: Masry-Herzallah Asmahan , Watted Abeer
Published: March 2024

During the COVID-19 outbreak, Israel’s higher education system swiftly transitioned to emergency-adapted online distance learning. Yet, limited research has assessed effectiveness of online learning (EOL) for Arab students in Israel. This study delves into Arab students’ EOL perceptions, focusing on cognitive and emotional aspects. Using a quantitative method, it explored the link between technological self-efficacy (TS), mindfulness ability (MA), and EOL during the pandemic among students from three Israeli academic institutions (N=378). Results showed a positive association between TS and EOL. Further, MA moderated TS-EOL relationship. Men demonstrated higher TS than women. There were noticeable EOL differences between undergraduate (pre-service teachers) and graduate (in-service teachers) students, with the latter exhibiting an advantage. This research contributes to the evolving discourse on post-pandemic online learning, shedding light on potential gender disparities and highlighting the importance of both TS and MA for successful online learning. The findings have implications for instructional designers, educators, policymakers, and academic programs.
Mitochondrial Dysfunction as a Factor of Energy Metabolism Disorders in Type 2 Diabetes Mellitus
Authors: Blagov Alexander , Nedosugova Ludmila , Kirichenko Tatiana , Sukhorukov Vasily , Melnichenko Alexandra , Orekhov Alexander
Published: March 2024

The pathogenesis of type 2 diabetes mellitus (T2DM) is based on the development of insulin resistance, which is a disruption to the ability of the tissues to bind to insulin, leading to a general metabolic disorder. Mitochondria are the main participants in cellular energy metabolism, meaning their dysfunction is associated with the development of insulin resistance in T2DM. Mitochondrial function is affected by insulin resistance in various tissues, including skeletal muscle and the liver, which greatly influence glucose homeostasis throughout the body. This review studies mitochondrial dysfunction in T2DM and its impact on disease progression. In addition, it considers the causes underlying the development of mitochondrial dysfunction in T2DM, including mutations in the mitochondrial genome, mitochondrial DNA methylation, and other epigenetic influences, as well as the impact of impaired mitochondrial membrane potential. New therapeutic strategies for diabetes that have been developed to target the mitochondria will also be presented.
Gender Differences in Patients with Atrial Fibrillation Receiving Oral Anticoagulants
Authors: Liao Jo-Nan , Huang Yu-Shan , Tsai Chuan-Tsai , Kuo Ling , Chen Su-Jung , Tuan Ta-Chuan , Chen Tzeng-Ji , Chen Shih-Ann , Chao Tze-Fan
Published: March 2024

Background: Gender is a well-recognized risk factor in atrial fibrillation (AF)-related ischemic stroke. The association of gender with the use of oral anticoagulants (OACs) and prognosis remains unknown. Methods: The National Health Insurance Research Database in Taiwan identified 203,775 patients with AF aged ≥20 years from 2012 to 2018, with 55.4% of males. Our main study cohort included 67,426 patients using OACs. The study endpoints include death, ischemic stroke, intracranial hemorrhage, major bleeding, and composite adverse events. Results: Significant differences were found in baseline characteristics between sexes. Female patients with AF were older and had higher CHA2DS2-VASc and HAS-BLED scores. Non-vitamin K antagonist oral anticoagulant (NOAC) use was more prominent in females while the use of warfarin was similar in both sexes. The distribution of baseline characteristics between the warfarin and NOAC groups in both sexes was much alike. Among the whole study cohort, NOAC was associated with a decreased risk of clinical endpoints compared to warfarin, which remained the same in subgroup analyses of both sexes. Additionally, a greater risk reduction of ischemic stroke with NOAC was observed in female patients compared to male patients (adjusted hazard ratio: 0.517 in males, 0.425 in females, interaction p = 0.040). Conclusions: This nationwide cohort demonstrated the differences between male and female patients with AF, including baseline characteristics, risk profiles, and medication use. Despite great differences in baseline demographic data, NOAC was associated with better clinical outcomes compared to warfarin in both sexes, and females benefited more than males in preventing ischemic stroke using NOACs.
Neoatherosclerosis: A Distinctive Pathological Mechanism of Stent Failure
Authors: Jiang Mengting , Zhang Yu , Han Yan , Yuan Xiaohang , Gao Lei
Published: March 2024

With the development of drug-eluting stents, intimal re-endothelialisation is significantly inhibited by antiproliferative drugs, and stent restenosis transforms from smooth muscle cell proliferation to neoatherosclerosis (NA). As a result of the development of intravascular imaging technology, the incidence and characteristics of NA can be explored in vivo, with some progress made in illustrating the mechanisms of NA. Experimental studies have shed light on the molecular characteristics of NA. More critically, sufficient evidence proves NA as a significant cause of late stent failure. Treatments for NA are still being explored. In this review, we summarise the histopathological characteristics of different types of stent NA, explore the potential relationship of NA with native atherosclerosis and discuss the clinical significance of NA in late stent failure and the promising present and future prevention and treatment strategies.
Modern possibilities for preventing the formation of liver fibrosis in children: the basics of preventive pediatric hepatology
Authors: Grigoryev K. I. , Kharitonova L. A.
Published: March 2024

Liver fibrosis is a natural outcome of almost any liver disease with a steady increase in incidence throughout the world. Considering the pathogenesis of liver fibrosis, the doctor-researcher is faced with the fact that the balance of regeneration processes in relation to the process of chronic inflammation is disturbed. The extracellular matrix accumulates in the liver tissue. Although this is a genetically determined process, but modifying factors play an important role in the progression of the disease. Liver fibrosis in its dynamic development leads to liver cirrhosis, hepatocellular carcinoma. Current data indicate the possibility of reversibility of liver fibrosis at any stage. Understanding the molecular mechanisms of the development of the pathological process is a key area of work for scientists involved in the development of antifibrotic therapy. The article discusses modern views on the prevention of the disease and the prospects for influencing the processes of liver fibrosis with an emphasis on childhood.
Epidemiological aspects of chronic diarrhea in children in the Samara region
Authors: Pechkurov D. V. , Tyazheva A. A. , Romanova A. A.
Published: March 2024

The aim of the research: to study the structure and epidemiological features of chronic diarrhea in children in different age periods. Materials and methods: data on outpatient cases of children and inpatient care with diseases that are clinically manifested by chronic diarrhea syndrome were analyzed. A survey of 1509 children of different ages was also conducted at an outpatient appointment with a pediatrician on the day of a healthy child, in preschool and educational institutions in the city of Samara. Results of the study: as a result of the study, it was revealed that in the structure of gastroenterological pathology in children, diseases manifested by chronic diarrhea account for 1.8%, while at the outpatient stage, unspecified diseases are more common. Among the children surveyed, it was found that clinical manifestations of chronic diarrhea were observed in 53.4% of cases at the time of the survey, while among these children, only 8% had a gastroenterological diagnosis that explained chronic diarrhea. Slightly less than half of the children surveyed had the so-called causal nature of chronic diarrhea. Conclusion: The relevance of the problem of chronic diarrhea in childhood is confirmed by the data of its high prevalence. It has been shown that insufficient attention is paid to the problem of chronic diarrhea - the registered prevalence is at least 5 times lower than the real one. Particular attention should be paid to children with cause-related diarrhea, and restriction of the use of cause-significant products stops clinical manifestations and leads to a decrease in seeking medical help.
Enhancing Dry Sliding Wear Resistance of Pure Mg by Plasma Electrolytic Oxidation Ceramic Coatings Using Silver Addition
Authors: SÖĞÜT Merve , AYDAY Aysun
Published: March 2024

This study investigated the wear effect on ceramic coated Mg by Plasma Electrolytic Oxidation. Three series of PEO coatings were prepared; one of was the effect of silicate electrolyte (5, 8, and 10 g/L) concentrations and the other was the effect of coating time (5, 10, 15 min), last one was the effect of AgNO3 (0.1, 0.2, 0.4 g/l) additive. The coatings were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD). The mechanical properties were analyzed by microhardness and linear wear test. The unlubricated wear resistance was observed by linear ball-on-disc tribometer. With increasing the silicate concentration, the average pore size and porosity percentage and the surface roughness increase. On the other hand, with increasing the coating time, the surface morphology gradually becomes flat. The coating time caused more compact and homogenous appearance. The surfaces coated with the addition of silver were obtained smoother and denser. The wear resistance of the high time coated Mg was significantly improved. The best wear resistance was obtained with silver-reinforced coatings.
A Single Source Thirteen Level Switched Capacitor Boost Inverter for PV applications
Authors: HEMANTH KUMAR B , JANARDHAN Kavali , JAVVAJİ Hemalatha , JYOTHİ B , MARTHANDA A.v.g.a , KADAM Deepak
Published: March 2024

This work proposes a module unit (MU) based single-source thirteen-level inverter (SSTLI) for solar PV applications. The proposed topology is 13-level design with single MU and 1.5 voltage gain. This work describes its operational modes at various output levels. Due to their symmetric functioning within a cycle, two capacitors were series-connected. with MU may achieve self-voltage balancing, which reduces complexity of control compared to typical Multilevel inverters (MLIs). The single-source generalized structure with additional MUs can be utilized in order to boost voltage levels for the output. With more MU, voltage gain increases, in addition the output levels are greatly enhanced. The merits of the proposed SSTLI are fewer components, self-balance, voltage stress. A comparison between proposed topology and other MLIs is shown in this work. To determine viability and dynamic performance of proposed SSTLI, MATLAB simulation results are presented for dynamic values of Modulation Index (M) for different loads along with the harmonic analysis. Experimental results also have been presented for the practicality of SSTLI topology.
Design Optimization and Analysis of Radial Flux Permanent Magnet Generator Using Local Optimization Method
Authors: MOSTAMAN Afıqah
Published: March 2024

Recently, Permanent Magnet Generator has been widely used due to its ability of having simple structure yet high efficiency. To maximise the output performance of the generator, advances and trends in mathematical modelling and computer simulation with using optimization techniques have opened the way to a new approach for electrical machine design. In this paper, a Radial Flux Permanent Magnet Generator configuration was examined and optimised throughout sizes and weight using Local Optimization Method as an iterative process in order to achieves optimal output. By utilizing LOM technique as optimization process, the output voltage of RFPMG increase by 13.64% from the initial results. With a corresponding increase in output voltage performances, the configurations geometry adjustment additionally helps in expanding the generator operational area.
The Effect of Short Carbon Fiber and Hydrothermal Carbon Content on Impact and Wear Properties of Epoxy Composites
Authors: KHLIFA Shokrı Salah M. , ÇUĞ Harun , ETİCHA Andinet Kumella , AKGÜL Yasin
Published: March 2024

This study aims to investigate the effect of different weight fractions (3%, and 5%) of short carbon fibers (SCFs) and hydrothermal carbons (HTCs) on the impact and wear properties of epoxy matrix composites. The samples were fabricated using the hand lay-up method. Izod impact tests were applied to the unnotched samples. To investigate the wear properties of pure epoxy and composites, reciprocating wear tests were conducted. Also, a Scanning Electron Microscope has been used for observation of the morphology of the broken and worn surfaces of pure Epoxy and (SCFs and HTCs) reinforced epoxy-based composites. Results showed that HTCs have remarkable effects on improving the wear resistance rate as compared to SCFs reinforced composites. However, SCFs reinforced epoxy composites have better energy-absorbing effects compared to HTCs epoxy-reinforced composites.
Structural and cation distribution analysis of Nickel-Copper/Nickel-Magnesium Substituted Lithium Ferrites
Authors: Parajuli D. , Samatha K.
Published: March 2024

Lithium ferrite (Li0.5Fe2.5O4) shows significant promise in electrical and electronic engineering. It possesses a crystal spinel crystal structure denoted as AB2O4, with "A" and "B" representing specific tetrahedral and octahedral lattice sites respectively. Analysis of X-ray diffraction (XRD) patterns aligns well with the JCPDS card (no. 38-0259), confirming the spinel structure with the Fd3m space group. However, an additional peak at 211 in the basic lithium ferrite suggests a subtle Fd3m to the P4132 phase change with a minor secondary hematite phase. Investigating the cation distribution in these ferrites is crucial for further exploration of their magnetic and dielectric properties. These ferrites find widespread applications in microwave technology and magnetic and electric energy storage devices.
Pengaruh Fartlek Training Pada Peningkatan Daya Tahan Aerobik Dan Anaerobik Atlit Hoki Ruangan Kota Jogja (The Effect of Fartlek Training on Increasing Aerobic and Anaerobic Endurance in Indoor Hockey Athletes in Jogja City)
Authors: Pribadi Agus , Widiyanto  , Alexander Bimo
Published: March 2024

Tujuan penelitian1ini adalah mengetahui pengaruh fartlek training pada peningkatan daya tahan aerobik dan1daya tahan anaerobik pada1atlit hoki ruangan putra Kota Jogja. Penelitian ini1merupakan jenis penelitian eksperimen, dengan1desain One Group Pretest-Posttest Design. Populasi pada penelitian ini yaitu atlit hoki ruangan putra Kota Jogja yang berjumlah 12. Teknik pengumpulan data pada penelitian ini adalah1bentuk tes. Alat ukur tes lari 2,4 km menggunakan metode Cooper Test guna mengukur daya tahan paru jantung dan1RAST Test guna mengukur daya tahan anaerobik. Analisis data yang dilakukan menggunakan Uji-t, dengan1cara membandingkan hasil pretest dan1posttest pada kelompok eksperimen. Berdasarkan hasil analisis data, dapat dilihat bahwa uji-t antara pretest dan posttest latihan fartlek terhadap1peningkatan daya tahan aerobik yang memiliki nilai t hitung sebesar 4,007 dan nilai t tabel dengan df = 11 pada taraf signifikan 5% sebesar 2,20. Nilai t hitung sebesar 4,007 > nilai t tabel sebesar 2,20, dan nilai p sebesar 0,002, karena p < 0,05 sehingga ada1perbedaan yang signifikan. Dilihat dari1nilai rata – rata kemampuan daya tahan aerobik, maka diperoleh nilai rata – rata pretest sebesar 12,58 dan nilai rata- rata posttest sebesar 11,31, karena1nilai rata – rata pretest > nilai rata – rata posttest maka terdapat1peningkatan kemampuan daya tahan aerobik sebesar 1,27/ 10,9%. Hasil analisis hipotesis kedua, dilihat bahwa uji-t antara pretest dan1posttest latihan fartlek pada1peningkatan daya tahan anaerobik memiliki nilai t hitung sebesar 22,951 dan1nilai t tabel dengan df 11 pada taraf signifikan 5 % = 2,20. Didapat nilai t hitung sebesar 22,951 > t tabel 2,20, dan nilai p sebesar 0,000, karena p lebih kecil dari 0,05 maka1terdapat perbedaan yang signifikan. Dilihat dari1nilai rata – rata kemampuan daya tahan anaerobik, maka1diperoleh nilai rata – rata pretest sebesar 305,16 dan rata – rata posttest sebesar 416,03, karena1nilai rata – rata pretest < nilai rata – rata posttest maka terdapat1peningkatan kemampuan daya tahan anaerobik sebesar 110,87/ 36,33 %. Dengan demikian dapat1disimpulkan bahwa terdapat pengaruh fartlek training pada peningkatan daya tahan aerobik dan daya tahan anaerobik pada atlit hoki ruangan putra Kota Jogja.
 
Kata kunci: fartlek training, daya tahan aerobik, dan daya tahan anaerobik.
Tingkat Pemahaman Tentang Recovery Terhadap Penurunan Asam Laktat Pada Mahasiswa Pendidikan Olahraga Universitas Muhammadiyah Jakarta
Authors: Muhammad Aspar  , M. Al Ghani  , Muhammad Ishaq Gery  , Taufik Yudi Mulyanto  , Surya Rezeki Sitompu
Published: March 2024

Penelitian ini bertujuan untuk mengetahui seberapa besar tingkat pemahaman mahasiswa pendidikan olahraga Universitas Muhammadiyah Jakarta yang mengikuti kuliah Pencegahan dan Perawatan Cidera dalam Olahraga Tentang Recovery Terhadap Penurunan Asam Laktat. Metode penelitian ini menggunakan jenis penelitian metode survey. Sasaran atau subjek dalam peneltian ini adalah mahasiswa pendidikan olahraga Universitas Muhammadiyah. Instrumen yang digunakan dalam penelitian ini adalah Test Soal yang digunakan untuk mengukur berapa besar pengetahuan mahasiswa tentang recovery untuk penurunan asam laktat. Adapun tahapannya sebagai berikut: (1) melalui tahapan; (2) mengkaji teori yang berkaitan dengan variabel yang diteliti; (3) menyusun indikator; (4) kompetensi pendaki yang diharapkan dari variabel; (5) menyusub kisi-kisi; (6) penyusunan butir pertanyaan; (7) skala pengukur. Berdasarkan data penelitian, mahasiswa basket memiliki pemahman tentang recovery terhadap penurunan asam laktat yaitu 18 orang untuk kategori baik dan 12 orang mahasiswa untuk kategori cukup.

 

 

Kata kunci :Asam Laktat, Basket, Pemahaman, Recovery