bluuebunny/crossref_metadata_2025 huggingface dataset:
Dravet syndrome in a 3-year-old pediatric patient: case report
Authors: K. Shailaja , L. Nissi , A. Tamil Arasi
Published: September 2022

Dravet syndrome (DS) is a severe form of epilepsy that occurs during the first year of life. This is caused by mutations in the voltage-gated sodium channel and characterized by frequent, prolonged seizures often triggered by high body temperature (hyperthermia), developmental delay, ataxia, hypotonia, sleep disturbances which is treated by multiple antiepileptic drugs. In this case report, we will discuss a 3 years old male pediatric patient who presented with complaints of vomiting and lethargies followed by seizures and has been diagnosed with DS since the age of 6 months. He was given with multiple antiepileptic drugs and other drugs for his symptomatic management which resulted in a major drug interaction. From this case report, we will get a clear picture necessitating continuous monitoring in case of polypharmacy.
A CONSTRUÇÃO DE CARROS DE BOI: CARAPINAS E SABERES TRADICIONAIS
Authors: Mendanha Túlio Fernando
Published: September 2022

Em torno da atividade de carapina (construtor de carro de boi) reúnem-se amplas dimensões heurísticas: conhecimentos técnicos tradicionais, a problemática do patrimônio/patrimonialização, ditames jurídicos, legislações ambientais e transmissão de saberes através do trabalho. Este artigo visa direcionar um olhar mais detido sobre a profissão ora estudada, buscando desdobrar, por sobre ela, uma visualidade mais crítica não apenas por parte da comunidade acadêmica, mas essencialmente por parte do poder público, demonstrando que o reconhecimento simbólico e a adoção de legislações jurídicas acerca deste ofício estendem-se a outras dinâmicas, sobre categorias como preservação/demarcação ambiental de determinada flora essencial para a profissão e a temática do patrimônio. Notar-se-á que a valorização e a produção de dispositivos legais acerca da construção dos veículos ora estudados também proporcionam um vislumbre mais apurado sobre toda a diversidade sociocultural religiosa referente à tradição da romaria em carros de boi em Trindade-GO.
Geospatial Public Policy: Global Best Practices for Harnessing the Potential of Satellite Technologies and Applications
Authors: Kaleagasi Bartu , McCarthy Sean , Beaumont Peter
Published: September 2022

This publication presents six case studies of public policies that promote the development and use of geospatial technologies and applications, which can be categorized in five layers: institutions, tools, data, skills and industry. The evolution of these technologies and applications over the past decade has been driven by the understanding that where people and things are located is central to smart decision making. As a result of low-cost launch vehicles, increasing numbers of satellites in orbit, new sensor technologies, machine learning algorithms, advances in cloud computing, and the emergence of other technologies such as drones and high-altitude platforms, the geospatial economy is now expanding into many new geographies and sectors. This expansion calls for the development of innovative applications that benefit government in areas such as agriculture, environment, energy, aviation, maritime, transport, health, education, business, and society.
Dekrety Konstytucji kwietniowej
Authors: Sarnecki Paweł
Published: September 2022

Autor w swojej pracy wraca do problemów dekretów Konstytucji kwietniowej, ale nie w kontekście historycznego zdarzenia. Nie milkną bowiem głosy o tym, że jakoby wybór przez Polskę, przed ćwierćwieczem, drogi systemu prezydenckiego i „rządzenia poprzez dekrety” byłby wyborem lepszym, skuteczniejszym, szybciej prowadzącym do osiągnięcia stanu szerokiego społecznego zadowolenia, ustabilizowania stosunków społecznych, zapewnienia wyższego stanu bezpieczeństwa i pewniejszego rozwoju kraju. Dla pełniejszej oceny badacz uznał, że warto będzie dogłębniej zbadać niżej opisany problem.
Stosunki cywilno-wojskowe pod rządem ustawy konstytucyjnej z 23 kwietnia 1935 r.
Authors: Witkowski Zbigniew , Szewczyk Michał
Published: September 2022

Przedmiotem rozważań Autorów będą: pozycja ustrojowa i zadania sił zbrojnych pod rządem Konstytucji kwietniowej; zwierzchnictwo Prezydenta nad armią, z osobnym omówieniem uprawnień dekretowych głowy państwa i określonej przy ich zastosowaniu organizacji naczelnych władz wojskowych; powiązania rządu oraz parlamentu z siłami zbrojnymi; praktyka ustrojowa lat 1935–1939.
Prawo do swobody wypowiedzi w prawie międzynarodowym i prawie polskim (na tle sporów o interes publiczny/demokratyzację polityki)
Authors: Zięba-Załucka Halina
Published: September 2022

Autorka w swoim opracowaniu zastanawia się nad prawem wolności słowa/prawem do swobody wypowiedzi. Analizuje je zarówno w kontekście prawa międzynarodowego, jak również prawa polskiego na tle sporów o interes publiczny/demokratyzację polityki.
Peran modal sosial sebagai solusi konflik pasca gempa bumi
Authors: Agung Yusuf Ratu , Yahya Yahya , Fuaturosida Rika , Ahda M. Naufal Firosa , Khotimah Khusnul , Hidayat Syamsul
Published: September 2022

ABSTRACTThe potential for post-disaster conflict often occurs in affected communities. Especially in the process of distributing incoming donations to each affected area. This study raises the topic of potential conflicts that arise after the earthquake in Malang. The conflicts that arise are motivated by several factors and their dynamics. In addition to the potential for post-earthquake conflict, this research tries to present a solution with the role of local community social capital in conflict resolution. The social capital found in the field is the value of harmony, racket, and mutua cooperation. The method used in this research is to use the theoretical framework of motives, incentives, and opportunities. The results of the study indicate that the potential for post-disaster conflict is based on the mental condition of the community which is still unstable and economic factors that are less stable due to the disaster. Thus, collaboration between the role of the stakeholder and social capital is needed to help earthquake survivors for surviving.KEY WORDSDisaster; Conflict; Social CapitalABSTRAKPotensi konflik pasca bencana kerap terjadi dalam masyarakat terdampak, Khususnya pada proses pendistribusian bantuan donasi yang masuk pada setiap daerah terdampak. Penelitian ini mengangkat topik terkait potensi konflik yang muncul pasca bencana gempa di Malang. Konflik yang timbul dilatar belakangi oleh beberapa faktor dan dinamikanya. Selain potensi konflik pasca gempa, penelitian ini berusaha menampilkan solusi dengan peranan modal sosial masyarakat setempat dalam penyelesaian konflik. Modal sosial yang ditemukan di lapangan yaitu nilai rukun, raket, dan gotong royong. Metode yang digunakan dalam penelitian ini berupa kualititaif dengan pendekatan studi kasus. Dari hasil penelitian menunjukkan timbulnya potensi konflik pasca bencana didasari pada kondisi masyarakat secara mental yang masih labil dan faktor ekonomi yang kurang stabil akibat bencana. Dengan demikian kolaborasi anatara peran stackholder dan modal sosial sangat dibutuhkan untuk membantu penyintas gempa bangkit kembali.KATA KUNCIBencana; Konflik; Modal Sosial
SPREADING LAUGHTER THROUGH HUMOR FROM GRICEAN MAXIMS AND ISLAMIC PERSPECTIVES
Authors: Fitria Andini Anugrah , Rohmah Zuliati
Published: September 2022

Humor is essential in maintaining the balance of human life socially and psychologically. Each culture in the world, including Islamic culture, perceives humor differently. Furthermore, from an academic perspective, humor can be constructed using linguistic features. Therefore, this study aims to examine verbal humor construction using linguistics features and evaluate how verbal humor is perceived by different cultures, particularly popular British and Islamic cultures. British popular culture is directed more toward the liberal culture, which is often opposed to the Islamic culture, which is often seen as conservative. By employing a qualitative approach, the study investigates the verbal humor construction in Black Books comedy series using Gricean cooperative maxim theory and Marzolph's concept of Islamic perspectives on humor based on the Holy Qur’an and Hadith. The results of this study point out that verbal humor utterances in the series flout and violate all four Gricean maxims, which are the maxim of quality (54.3%), quantity (14.3%), relevance (11.4%), and manner (20%). This study also found that most verbal humor utterances in the series are appropriate to Islamic perspectives on humor, as 60% of the verbal humor utterances do not contain ridicule, defamation, offensive utterances and name-calling, and some other forbidden acts in Islam such as lies and abusive behaviors. The results of this study are expected to provide more insights into verbal humor construction and different cultures' perspectives on verbal humor.
Disponibilidad a pagar para mitigar las emisiones urbanas: un abordaje desde los hogares, Ibagué-Colombia
Authors: Sierra Ramírez Erika , Andrade Hernán J. , Segura Milena A.
Published: September 2022

Acelerar la implementación de acciones que disminuyan las emisiones de gases de efecto invernadero (GEI) es necesario. Por ello, se estimó la disponibilidad a pagar (DAP) de los hogares de Ibagué para mitigar las emisiones de GEI derivadas del consumo de combustibles fósiles y energía eléctrica. Se empleó el método de valoración contingente para conocer la DAP mediante entrevistas semiestructuradas. El 38 % de las 1816 familias encuestadas tienen DAP para mitigar las emisiones de GEI en sus hogares, aportando de manera voluntaria en promedio $33.9871/hogar/año. Por lo tanto, en el escenario de implementar mercados obligatorios y voluntarios de carbono en el 38 % del total de los hogares de la ciudad, se lograría mitigar entre 3 y 86 % del total de las emisiones (169 mil t CO2 emitidas en los hogares al año).
Efectos de la pandemia en la participación laboral, las actividades económicas y familiares de las mujeres en Popayán-Colombia
Authors: Atis Ortega Karen Liseth , Cano Pajoy Diana Carolina , Fajardo Hoyos Claudia Liceth
Published: September 2022

El artículo analiza las afectaciones de la pandemia por Covid-19 en el mercado laboral, en las actividades económicas y familiares de las mujeres en la ciudad de Popayán y las empresarias del Cauca. Para ello, se estima un modelo logit, además se utilizan fuentes de información primaria y secundaria provenientes del DANE, ANIF y Confecámaras. Los resultados muestran que la brecha en participación laboral para las mujeres se incrementó en aproximadamente 1,2 puntos porcentuales, los datos obtenidos, a través de 298 empresarias encuestadas, revelan que estas han tenido que cambiar su actividad económica, hacer uso de las TIC y otras estrategias para adaptarse a las dificultades coyunturales. Finalmente se observó un importante cambio en la actividad económica de las empresas, pocos emprendimientos dirigidos por mujeres están operando a plena capacidad, mientras que la mayoría se encuentran operando con restricciones, cerrados o en proceso de cierre.
Exercise-induced traumatic muscle injuries with active bleeding successfully treated by embolization: three case reports
Authors: Heo Yoonjung , Kang Hye Lim , Kim Dong Hun
Published: September 2022

Muscle injuries caused by indirect trauma during exercise are common. Most of these injuries can be managed conservatively; however, further treatment is required in extreme cases. Although transcatheter arterial embolization is a possible treatment modality, its role in traumatic muscle injuries remains unclear. In this case series, we present three cases of exercise-induced muscle hemorrhage treated by transcatheter arterial embolization with successful outcomes. The damaged muscles were the rectus abdominis, adductor longus, and iliopsoas, and the vascular injuries were accessed via the femoral artery during the procedures.
Telemedicine for sarcoma patient care
Authors: Schuetze Scott M.
Published: September 2022

Telemedicine is being incorporated into routine healthcare, including oncology. The integration of telemedicine with patient electronic medical records and the adoption of virtual provider-patient encounters was accelerated by the SARS-CoV2 worldwide pandemic. Although telemedicine has existed for more than 50 years, the impact of telemedicine on patient care and health outcomes is relatively understudied, and little research has been conducted on telehealth in the care of patients with sarcoma. This review discusses the potential applications of telemedicine to the care of patients with sarcoma and some of the data available on patient and provider preferences for telemedicine vs. in-person healthcare encounters. Some of the areas of care in which greater adoption of telemedicine may be beneficial to patients with sarcoma are also discussed.
Detection of Waste Plastics in the Environment: Application of Copernicus Earth Observation data
Authors: Lavender Samantha
Published: September 2022

The detection of waste plastics in the marine and terrestrial environment using satellite Earth Observation data offers the possibility of large-scale mapping, and reducing on-the-ground manual investigation. In addition, costs are kept to a minimum by utilizing free-to-access Copernicus data. A Machine Learning based classifier was developed to run on Sentinel-1 and -2 data. In support of the training and validation, a dataset was created with terrestrial and aquatic cases by manually digitizing varying landcover classes alongside plastics under the sub-categories of greenhouses, plastic, tyres and waste sites. The trained classifier, including an Artificial Neural Network and post-processing decision tree, was verified using five locations encompassing these different forms of plastic. Although exact matchups are challenging to digitize, the performance has generated high accuracy statistics, and the resulting land cover classifications have been used to map the occurrence of plastic waste in aquatic and terrestrial environments.
Suppression of CircTCF4 on the Proliferation and Differentiation of Goat Skeletal Muscle Satellite Cells
Authors: Zheng Shuailong , Li Li , Zhou Helin , Zhang Xujia , Xu Xiaoli , Dai Dinghui , Zhan Siyuan , Cao Jiaxue , Guo Jiazhong , Zhong Tao , Wang Linjie , Zhang Hongping
Published: September 2022

The proliferation and differentiation of mammalian skeletal muscle satellite cells (MuSCs) are highly complicated. Apart from the regulatory signaling cascade driven by the protein-coding genes, non-coding RNAs like microRNAs (miRNA) and circular RNAs (circRNAs) play essential roles in this biological process. However, circRNA functions in MuSCs proliferation and differentiation remain largely to be elucidated. Here, we screened for an exonic circTCF4 based on our previous RNA-Seq data, specifically expressed during the development of the longest dorsal muscle in goats. Subsequently, the circular structure and whole sequence of circTCF4 were verified using Sanger sequencing. Besides, circTCF4 was spatiotemporally expressed in multiple tissues from goats but strikingly enriched in muscles. Furthermore, circTCF4 suppressed MuSCs proliferation and differentiation, independent of AGO2 binding. Finally, we conducted Poly(A) RNA-Seq using cells treated with small interfering RNA targeting circTCF4 and found that circTCF4 would affect multiple signaling pathways, including insulin signaling pathway and AMPK signaling pathway related to muscle differentiation. Our results provide additional solid evidence for circRNA regulating skeletal muscle formation.
Does Governance Matter? Community-Participatory Governance and Conflict Management as Instruments for Administering Development in Sub-Saharan Africa
Authors: Aleer Machol Joseph
Published: September 2022

This study provides an insightful overview of community-participatory governance and conflict management as instruments for utilizing resources for development in Sub-Saharan Africa (SSA). SSA is a region rich in natural resources but prone to conflict. The study is conceptual and critically engages the application of community governance and conflict management strategies that SSA countries need to adopt. The study praises the notion that community governance is characterized by recognizing and accepting intercultural diversity and creating a democratic institution for promoting good governance and conflict management in SSA. The study recommends that good community governance is required to drive local communities' development, growth, and transformation into a sturdy, innovative, and productive society capitalizing on opportunities. The study voice for the amalgamation of appropriate models and theories of governance cogently in the context of SSA due to the heterogeneity of communities. Therefore, to resolve conflict, conflict management, resolution, and transformation strategies are necessarily needed to accomplish a viable peace to maintain and sustain development.
Manfred Deistler and the General Dynamic Factor Model Approach to the Analysis of High-Dimensional Time Series
Authors: Hallin Marc
Published: September 2022

For more than half a century, Manfred Deistler has been contributing to the construction of the rigorous theoretical foundations of the statistical analysis of time series and more general stochastic processes. Half a century of unremitting activity is not easily summarized in a few pages. In this short note, we chose to concentrate on a relatively little-known aspect of Manfred's contribution which nevertheless had quite an impact on the development of one of the most powerful tools of contemporary time series and econometrics: dynamic factor models.
Influence of different types of margins in the fish assemblage from an urban river
Authors: Soinski Thais Aparecida , Pinheiro Lucio Antônio Stefani , Cavallari Daiane Elen , Stefani Marta Severino , Smith Welber Senteio
Published: September 2022

The presence or absence of a fish species may be associated with the physical and chemical characteristics of the water, in addition to the state of preservation of the riparian zone. This study examined whether the taxonomic fish composition in an urban river varies along three riparian zone preservation conditions: preserved, intermediate preservation and degraded. Six urban stretches of the Sorocaba/São Paulo River were selected for this study, with monthly sampling being carried out from June 2019 to February 2020. The samplings were carried out with the aid of a sieve, dip net, and trawl. Regarding the types of margins and environmental variables, the Principal Component Analysis explained 97.49% of the data variation, axis 1, which explained 91.85% of the total variation, was formed by the variables conductivity and total dissolved solids. Axis 2, which explained 5.64% of the variation, was formed by Sun Rays% and Siltation%, being inversely proportional to Riparian Forest%. For the ichthyofauna, the samples consisted in 50,983 fish distributed in 5 orders, 8 families, and 12 species. Cyprinodontiformes had the highest abundance, with 96.96% of the total number of individuals, followed by Siluriformes (2.39%), and the sum of the other orders did not reach 1% of the total collected. According to each type of margin, it was possible to register 11,592 individuals for the Margin A í  preserved, with S=8 species, being 2 exclusive (Corydoras flaveolus and Hoplosternum littorale) and 3 exotic (Coptodon rendalli, Pterygoplichthys ambrosettii, and Poecilia reticulata), the latter was dominant in all types of margins. For Margin B í  intermediate preservation, 19,645 individuals were sampled, with S=5 species, no exclusive species, only exotic and more tolerant native species such as Hoplias malabaricus and Hypostomus ancistroides. For Margin C í  degraded, 19,746 individuals were recorded, the largest number of species (S=10), 3 were exclusive to this type of margin (Psalidodon fasciatus, Rhamdia Quelen, and Geophagus brasiliensis). The pairwise comparison (similarity percentage) showed that the assemblage structure was different for the types of margins. The Canonical Correspondence Analysis explained 92.46% of the total data variation, showing the relationship of species to environmental data. It is evident the importance of preservation of micro-habitats still present in the locals sampled, since different anthropic pressures cause great loss of diversity, especially for native and more sensitive species.
Geographic information system as a tool for assessing ponds and the potential for environmental impact caused by fish farming
Authors: Morsoleto Felipe Silva , LIRA Karen Carrilho da Silva , SILVA Jhony Ferry Mendonça da , FRANCISCO Humberto Rodrigues , BITTENCOURT Fabio , FEIDEN Aldi
Published: September 2022

The hydrographic basin of Arroio Marreco (Paraná State) concentrates a productive chain of fish farming and great intensification of tilapia farming. In this study, we aimed to monitor the quality of effluent water and organic and inorganic elements released by fish farming in ponds, using geomorphological and land-use and occupation data. The Terrain Analysis Using Digital Elevation Models, Digital Elevation Model software was used to delimit watersheds in the software Quantum geographic information system version 3.6.3. A total of 1,457 production units (water slides) were identified across the study area. This represented an occupied area of 160.2 ha. Analyzing the sub-basins, it was found that High Marreco is the sub-basin with the most developed logistical chain. Low Marreco does not yet have an integration of its fish farming with the regionââ‚¬â„¢s logistics chain. Medium Marreco does not have fish farming as its main activity, only using it to reuse inputs from other agricultural activities. There is a large input of nutrients from aquaculture in all the sub-basins. To reduce them, it is recommended to implement decantation and/or reuse of wastewater systems. The results of this study show how important it is to know the dynamics of nutrients in the fish farms and the physical characteristics of the drainage basin to determine the support capacity of the environment, so as not to allow licenses that promote impacts above the self-cleaning capacity of the courses water.
Risk of Noise-Induced Hearing Loss for Orthopaedic Surgeons
Authors: Kwan Stephanie A. , Lynch Jeffrey C. , DeFrance Michael , Ciesielka Kerri-Anne , Rivlin Michael , Daniel Joseph N.
Published: September 2022

Background:

Noise-induced hearing loss (NIHL) affects the ability of an individual to communicate and can negatively impact quality of life. The risk to orthopaedic surgeons of developing NIHL as a result of occupational exposures in the operating room (OR) is currently unknown. Hearing protection is recommended for levels of >85 decibels (dB), irrespective of length of exposure. The primary goal of the present study was to determine whether orthopaedic surgeons are exposed to harmful noise levels in the OR that puts them at risk for developing NIHL.

Methods:

A prospective review was conducted with use of intraoperative audio recordings across 6 orthopaedic subspecialties. Recordings were made in ORs prior to the surgical start time to serve as baseline controls. Decibel levels were reported as the maximum dB level (MDL), defined as the highest sound pressure level during the measurement period, and as the time-weighted average (TWA), defined as the average dB level projected over an 8-hour time period. Noise doses were reported as the percentage of maximum allowable daily noise (dose) and as the measured dose projected forward over 8 hours (projected dose).

Results:

Three hundred audio recordings were made and analyzed. The average MDL ranged from 96.9 to 102.0 dB, with noise levels for all subspeciality procedures being significantly greater compared with the control recordings (p < 0.001). Overall, MDLs were >85 dB in 84% of cases and >100 dB in 35.0% of cases. The procedure with the highest noise dose was a microdiscectomy, which reached 11.3% of the maximum allowable daily noise and a projected dose of 104.1%. Among subspecialties, adult reconstruction had the highest dose and projected dose per case among subspecialties.

Conclusions:

The present results showed that orthopaedic surgeons are regularly exposed to damaging noise levels (i.e., >85 dB), putting them at risk for permanent hearing loss. Further investigation into measures to mitigate noise exposure in the OR and prevent hearing loss in orthopaedic surgeons should be undertaken.

Clinical Relevance:

Orthopaedic surgeons are at risk for NIHL as a result of occupational exposures in the OR.
Study on the Mobility and Flow Mechanism of Aquifer Water in Carbonate Gas Reservoirs
Authors: Li Zhongcheng , Fang Feifei , Zhai Yujia , Zhang Jie , Li Zhi
Published: September 2022

Water invasion is one of the most critical constraints on developing carbonate gas reservoirs, with a significant impact on gas well production. Therefore, it is crucial to establish a correct experimental model of water invasion to study the mobility and flow mechanism of aquifer water. In this study, three-full-diameter core was selected from Longwangmiao carbonate gas reservoirs. Then, the experimental evaluation methods and process of aquifer water mobility are established and conducted, and the effects of different parameters on the mobility of aquifer water are analyzed. The results show that the mobility of aquifer water is affected by the pore compressibility of formation rock and its elastic expansion. The proportion of movable water per unit drawdown pressure is 0.1%/MPa, which has little relationship with the production pressure difference. The formation drawdown pressure is the key factor controlling the mobility of the aquifer water. The greater the formation drawdown pressure, the higher the proportion of movable water in aquifer water, and the stronger the degree of water invasion. The cumulative movable water accounted for 6%-9% of the aquifer water in the development of carbonate gas reservoirs, and the final movable water production is related to the abandonment pressure. The aquifer water did not flow initially with drawdown pressure, but there was a critical drawdown pressure with the value of 10 MPa to 13 MPa, and it has a negative association with reservoir permeability. The finding of this study can help for better understanding the concept of water invasion in formation water-bearing reservoirs, and these results can fill the gaps in the mobility conditions and flow mechanisms of aquifer water and provide technical reference for optimizing water-invasion carbonate gas reservoir development.
Laboratory Comparative Study of Anionic and Cationic High-Viscosity Friction Reducers in Moderate to Extremely High Total Dissolved Solids Environments
Authors: Ge Xiaojing , Imqam Abdulmohsin
Published: September 2022

High-viscosity friction reducers (HVFRs) have been recently gaining more attention and increasing in use, not only as friction-reducing agents but also as proppant carriers. Reusing produced water has also been driven by both environmental and economic benefits. Currently, most friction reducers on the market are anionic friction reducers, which are fully compatible with most produced water with low to medium level of total dissolved solids (TDS) but show a significant drop at high TDS conditions in terms of their friction reduction performance in most cases. On the contrary, cationic friction reducers are believed to have better TDS tolerance and friction reduction performance under high TDS conditions. However, concerns remain about performance of using anionic and cationic HVFRs with produced water to transport proppant. The ultimate objective of this experimental study is to comparably analyze the proppant transport capabilities of anionic and cationic HVFRs in high TDS and reservoir temperature environments. An anionic HVFR and a cationic HVFR, both at 4 gallons per thousand gallons (GPT), were selected and analyzed. The rheology measurements of these anionic and cationic HVFRs were conducted in deionized (DI) water and high TDS water conditions. Static and dynamic proppant settling tests were conducted at various TDS conditions at reservoir temperature. Wall retardation and particle hindering on the performance of both anionic and cationic HVFRs were also observed and investigated using the particle image velocimetry (PIV) method. The results showed that the anionic HVFR had higher viscosity than the cationic HVFR due to larger molecular weight and had much higher elasticity. Increase in TDS concentration would decrease the viscous and elastic profiles of both anionic and cationic HVFRs. In particular, the elastic profile became negligible for both HVFRs. Besides, the “critical salinity” phenomenon was observed. Above this salinity, the viscosity of HVFRs was no longer affected by increasing TDS level. The “critical salinity” for both of the 4-GPT anionic and cationic HVFRs was in the range of 30 000 to 200 000 mg/L. Moreover, the cationic HVFR had lower “critical salinity” than the anionic HVFR. Finally, the correlation between rheology and proppant transport capabilities of HVFRs is discussed in this paper, and a simplified decision-making process of selecting fracturing fluids is proposed.
Petroleum Geostatistics
Authors: Caers Jef
Published: September 2022

Petroleum Geostatistics provides an overview of the role of geostatistical methods in reservoir modeling, focusing on well-seasoned geostatistical tools, their versatility, and their inherent limitations. The author provides ample tutorial synthetic examples, as well as real-case demonstrations illustrating practicality, and writes in an intuitive, conceptualizing style devoid of a burdensome mathematical treatment of the field. This title is geared toward professional geologists, geophysicists, and petroleum engineers looking for a first exposure to geostatistics, but it also can be used as a textbook on the practical aspects of geostatistics in reservoir modeling.
Data-Driven Reservoir Modeling
Authors: Mohaghegh Shahab D.
Published: September 2022

Data-Driven Reservoir Modeling introduces new technology and protocols (intelligent systems) that teach the reader how to apply data analytics to solve real-world, reservoir engineering problems. The book describes how to utilize machine-learning-based algorithmic protocols to reduce large quantities of difficult-to-understand data down to actionable, tractable quantities. Through data manipulation via artificial intelligence, the user learns how to exploit imprecision and uncertainty to achieve tractable, robust, low-cost, effective, actionable solutions to challenges facing upstream technologists in the petroleum industry.
Waterflooding: Injection Regime and Injection Wells
Authors: Chappell Dave
Published: September 2022

Used successfully for more than a century, waterflooding remains the most widely performed process relying on an external energy source to maximize reservoir recovery. Multiple factors across a wide range of disciplines contribute to the delivery of a fully optimized project, but not all of these critical success factors have been well-documented. A focus on further optimizing all the varying parts of the process has emerged over time to deliver project success. Waterflooding: Injection Regime and Injection Wells explores the benefits and drawbacks of both matrix and fractured injection and reviews the impacts that these injection regimes can have on waterflood performance.
Waterflooding: Facilities and Operations
Authors: Chappell Dave
Published: September 2022

Used successfully for more than a century, waterflooding remains the most widely performed process relying on an external energy source to maximize reservoir recovery. Multiple factors across a wide range of disciplines contribute to the delivery of a fully optimized project, but not all of these critical success factors have been well-documented. A focus on further optimizing all the varying parts of the process has emerged over time to deliver project success. Waterflooding: Facilities and Operations looks at the design of injection and production systems and how they influence success in waterflooding.
Lost Circulation: A New Approach to An Old Challenge
Authors: Taoutaou Salim , Cook John , Russell Ken
Published: September 2022

Lost circulation has been a persistent and costly challenge in the oil and gas industry. However, recent advances in geomechanics, drilling techniques and fluids, cementing and lost circulation fluids, logging while drilling and data analytics, are now assisting the industry to resolve lost circulation issues more effectively. In the SPE PetroBrief, Lost Circulation: A New Approach to An Old Challenge the authors discuss the present understanding of lost circulation and provide current examples of new techniques being applied to resolve these age-old challenges.
Low Invasion Coring: Best Practices Regarding Objectives, Planning, Equipment, Materials, Execution, and Follow-Up
Authors: Bloys J.B. , Warner H.R.
Published: September 2022

The latest addition to SPE’s Monograph Series, Low Invasion Coring will help readers develop an understanding of how to apply the array of technologies required for successful completion of a low-invasion coring (LIC) project. This monograph addresses the principles of obtaining low-invasion cores and provides essential practical tips for engineering field LIC projects. Appendices provide detailed information on specific core-analysis procedures. .
Plant Seed-Based Bio-coagulant Development and Application for Fecal Sludge treatment and Biogas Production Improvement.
Authors: DIMA Francis Auguste Fleury Junior , LI Zifu , ZHOU Xiaoqin , ZHU Lixin
Published: September 2022

This work addresses the development and application of Cucumeropsis mannii and Luffa acutangula seed proteins as novel bio-coagulants for fecal sludge concentration to increase the biogas yield. The seed protein content was determined and extracted using 1M NaCl, isolated and precipitated by ammonium sulfate [(NH₄)₂SO₄], and dialyzed to obtain the purified proteins. Their coagulation/flocculation was compared to Moringa oleiefera and pumpkin seeds as the primary treatment for the fecal sludge concentration. Optimal coagulant dosages of 20 mg/l at pH 7.25 increased the total solids from 0.4–2.8% and obtained 180 to 350 ml/l of fecal sludge volume per liter. The bio-coagulants effect on the supernatant water reduced 71.20% to 96,88% of turbidity, 76.48–88.70% of COD, and 81.33 to 95.30% of ammonia nitrogen. The BMP result has shown that plant seed-based bio-coagulant are effective and triple the methane yield result compared to the FS without bio-coagulant treatment with a specific methane yield of 192.8 NmL CH4/gVS, and FS with bio-coagulant pretreatment was increased up 350.5 to 465.3 NmL CH4/gVS, with a ratio 2:1 on VS basis.
Forty years (1981-2021) assessing stigma with the Community Attitudes to Mental Illness (CAMI) scale: systematic review of psychometric properties
Authors: Bernadàs Albert , Doval Eduardo , Angarita-Osorio Natalia , Sanabria-Mazo Juan P. , Colomer-Carbonell Ariadna , Evans-Lacko Sara , Thornicroft Graham , Luciano Juan Vicente , Rubio-Valera Maria
Published: September 2022

Background.The Community Attitudes to Mental Illness (CAMI) scale measures social stigma towards people with mental illness. Although it has been used worldwide, the psychometric properties of the CAMI have not been systematically reviewed. The main aim of the present work was to systematically review the psychometric properties (dimensionality, reliability, and construct validity) of the different versions of the CAMI 40 years after of its publication.Methods.A systematic search was conducted in PubMed, PsycINFO, Web of Science, and EMBASE from January 1981 to June 2021. A double review was performed for eligibility, data extraction, and quality assessment.Results.A total of 13 studies enrolling 10,095 participants were included. The most frequently reported factor structure comprises 3 or 4 factors. The internal consistency seems adequate for the global scale (a≥ 0.80), except for CAMI-10 (a= 0.69). Overall, internal consistency of the sub-scales is not supported, with authoritarianism being the weakest factor (a= 0.27 to 0.68). The stability over time of the total scale has been assessed in the CAMI-BRand CAMI-10(r> 0.65). Few studies have assessed the temporal stability of the CAMI subscales. Most of the correlations with potentially related measures are significant and in the expected direction.Conclusions.The 3-4 factor structure is the most widely reported in the different versions of the CAMI. Although the reliability and construct validity are acceptable, further item refinement by international consensus seems warranted 40 years after the original publication.PROSPERO registration number:CRD42018098956
Defining “successful” treatment outcomes in adolescent idiopathic scoliosis: a scoping review
Authors: Joarder Ishraq , Taniguchi Seika , Snow Mary Elizabeth , Mendoza Andrea
Published: September 2022

Purpose
Adolescent idiopathic scoliosis (AIS) is the most common type of scoliosis that affects children aged 10 to 18 years old, manifesting in a three dimensional spinal deformity. This study aimed to explore outcome measures used in defining AIS treatment success. Particularly, analyzing the extent of radiographic and quality of life domains used and whether AIS treatment approaches (surgical, bracing, physiotherapy etc.) influences outcomes used as proxies of treatment success.
Methods
EMBASE and MEDLINE databases were used to conduct a systematic scoping review with 158 papers screened for data extraction. Extractable variables included: study characteristics, study participant characteristics, type of study, type of intervention approach and outcome measures.
Results
All 158 studies measured quantitative outcomes. 61.38% of papers used radiographic outcomes whilst 38.62% of papers used quantitative quality of life outcomes to evaluate treatment success. Irrespective of treatment intervention utilized, the type of quantitative outcome measure recorded did not differ significantly. Moreover, of the radiographic outcome measures, the subcategory Cobb angle was predominantly used across all intervention approaches. For quantitative quality of life measures, questionnaires investigating multiple domains such as SRS were primarily used as proxies of AIS treatment success across all intervention approaches.
Conclusion
This study identified that no articles employed qualitative measures of describing the psychosocial implications of AIS in defining treatment success. Although quantitative measures have merit in clinical diagnoses and management, there is increasing value in using qualitative methods such as thematic analysis in guiding clinicians to develop a biopsychosocial approach for patient care.
Hepatotoxicity and Nephrotoxicity induced by fipronil and lead acetate and their mixture as well as evaluation of therapeutic effects of camel milk against their harmful.
Authors: Abdel-Mobdy Yasmin , Abdel-Mobdy Ahmed E. , Farga Ammar AL
Published: September 2022

Elevated environmental pollution of lead and fipronil blamed for chronic toxicity. Fipronil and lead acetate are commonly used but now no adequate data available concerning side harmful of their mixture. The present work studied the curative effects of camel milk against lead and fipronil toxicity individually and their mixture. The lead acetate or fipronil and their mixture significantly induction deteriorated kidneys and liver function parameters as well as lipid profile and oxidative stress in the both organs. Serum LDH activity increased under the same conditions. Histological examination revealed hepatic degeneration, nephropathy in intoxicated rats relative to normal health control. Both toxicants in their mixture showed more harmful than those of its individual ones. Camel milk treatments into intoxicated animals (lead, fipronil and mixture groups) attenuated the all evaluated parameters, also alleviated the harmful influences of the mixture of lead acetate and fipronil and improved the biomarkers of their oxidative stress.
Multiple-year farm-level assessments of trade-offs between GHG emissions and income: case examples of two farming systems in Northern Nigeria
Authors: Ayinde Taiwo Bintu , Nicholson Charles F. , Ahmed Benjamin
Published: September 2022

This study quantifies the trade-offs between welfare (measured by income) and greenhouse gas (GHG) emissions in two farming systems of northern Nigeria using data for five years from 2015 to 2019. The analyses employ a farm-level optimization model that maximizes value of production less purchased input costs for agricultural activities including production of trees (Locust Bean or Camel’s Foot), sorghum, groundnut or soybeans and multiple livestock species. We compare income and GHG emissions without constraints to scenarios requiring reductions in emissions of either 10% or the maximum reduction feasible while maintaining minimum household consumption levels. For both locations and all years, we find that reductions in GHG emissions would lower household incomes and require substantive modifications to production patterns and input use. However, the extent to which reductions are possible and the patterns of income-GHG trade-offs vary, indicating that such effects are site-specific and time-variable. The variable nature of these trade-offs suggests challenges for the design of any program that would that seek to compensate farmers for reductions in their GHG emissions.
Symbiotic microbiome Staphylococcus epidermidis restricts IL-33 production in allergic nasal epithelium via limiting the cellular necroptosis
Authors: Jeon Yung Jin , Gil Chan Hee , Won Jina , Jo Ara , Kim Hyun Jik
Published: September 2022

Background
Allergic rhinitis (AR) is characterized by airway inflammation in nasal mucosa from inhaled allergens and interleukin (IL)-33 is the potent inducer of Th2 inflammation in allergic nasal epithelium. Staphylococcus epidermidis is one of the most abundant colonizers of the healthy human nasal mucosa and might impact the allergen-induced inflammatory responses in the nasal epithelium. Thus, we sought to characterize the mechanism of S. epidermidis regulating Th2 inflammation and IL-33 production in AR nasal mucosa. We isolated nasal commensal S. epidermidis from four healthy donors and determined the anti-allergic effect of S. epidermidis in normal human nasal epithelial (NHNE) and AR nasal epithelial (ARNE) cells and AR mice models.
Results
The AR symptoms were alleviated and eosinophilic infiltration, serum IgE levels, and Th2 cytokines were significantly decreased in OVA-sensitized AR mice in response to human nasal commensal S. epidermidis. The inoculation of S. epidermidis to NHNE cells reduced IL-33 and GATA3 transcriptions and also reduced IL-33 and GATA3 expression in ARNE cells and the nasal mucosa of AR mice. Our data exhibited that the cellular necroptosis of ARNE cells might be involved in IL-33 production and inoculation of S. epidermidis decreased the phosphorylation of necroptosis enzymes in ARNE cells, which was related to the reduction of IL-33 production.
Conclusions
Our findings indicate that human nasal commensal S. epidermidis reduces allergic inflammation by suppressing IL-33 production in nasal epithelium and blocking allergen-induced cellular necroptosis via S. epidermidis might be a key mechanism of reduction of IL-33 in allergic nasal epithelium.
Relationship between maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study in China
Authors: Ma Linghua , Li Jiangheng
Published: September 2022

Background: Maternal age at childbearing has been dramatically increasing worldwide. The problems of adverse obstetric outcomes caused by extremes of maternal ageare more common. This study aimed to analyze the associations between maternal age and the risk of adverse pregnancy outcomes.
Methods: We performed a population-based study consisting of 108,706 singleton pregnant women whose newborns were delivered after 20 weeks' gestation between January 2012 and December 2015 in China. Participants were divided into four groups according to maternal age at delivery (19 years or younger; 20-34 years; 35-39 years; 40 years or older). Logistic regression models were used to assess the associations between maternal age and adverse pregnancy outcomes with women aged 20–34 years as the reference group.
Results: Advanced maternal agewas associated with an elevated risk of almost all adverse pregnancy outcomes. Young maternal age was associated with increased risk of preterm birth (RR 1.48, 95% CI 1.31–1.67), low birth weight (RR 1.69 95% CI 1.51–1.90), small for gestational age (RR 1.44, 95% CI 1.32–1.57), an Apgar score < 7 at 5 min (RR 1.54, 95% CI 1.08–2.21), and fetal death (RR 1.82, 95% CI 1.22–2.71), as well as decreased risk of gestational diabetes mellitus (RR 0.20, 95% CI 0.13–0.29), gestational hypertension (RR 0.29, 95% CI 0.15–0.56), preeclampsia (RR 0.29, 95% CI 0.17–0.50), premature rupture of membranes (RR 0.29, 95% CI 0.22–0.39), postpartum hemorrhage (RR 0.50, 95% CI 0.33–0.76), cesarean delivery (RR 0.42, 95% CI 0.39–0.47), macrosomia (RR 0.34, 95% CI 0.23–0.49), and fetal distress (RR 0.48, 95% CI 0.38–0.61).
Conclusions: Advanced maternal age predisposes women to adverseobstetric outcomes. Young maternal age manifests a bidirectional effect on adverse pregnancy outcomes. The findings can be used to improve women's antenatal care and management.
Preparation of oxidized nanocellulose by using potassium dichromate
Authors: Makhliyo Kuzieva , Abdumutolib Atakhanov , Sirojiddin Shakhobutdinov , Nurbek Ashurov , Khaydar Yunusov , Jiang Guohua
Published: September 2022

Nanocellulose (NC) derivatives are being used in a wide variety of high-quality functional applications. One of them is oxidized nanocellulose (ONC), which has been used in biomedical and pharmaceutical applications due to its biodegradable, biocompatible, hemostatic, and antibacterial properties. In this work, ONC was synthesized using potassium dichromate as an oxidizing agent. The structure of ONC was investigated by means of ultraviolet spectrophotometry (UV), fourier transforms infrared spectroscopy (FTIR), X-ray diffraction (XRD), atomic force microscopy (AFM), and thermogravimetric analysis (TGA). The results showed that the primary hydroxyl groups of NC were selectively oxidized to carboxyl groups and their content of 1.36 mmol/g was achieved. The appearance of a new peak (1721 cm− 1) in the FTIR- spectra related to the C = O group was observed. The change of ONC degree of crystallinity (DC) from 88.0–82.5% was revealed and the sizes of the unit cells of both NC and ONC were calculated. The thermal stability of ONC decreased compared to NC. The oxidation process of NC leads to a change in the shape and size of particles from acicular to spherical with a narrow particle size distribution. It was shown that ONC has the ability to accumulate charge on its surface.
Evidence for field induced quantum spin liquid behavior in a spin-1/2 honeycomb magnet
Authors: Lin Gaoting , Zhao Qirong , Li Gang , Shu Mingfang , Ma Yinina , Jiao Jinlong , Huang Qing , Sheng Jieming , Kolesnikov Alexander , Li Lu , Wu Liusuo , Wang Xiaoqun , Zhou Haidong , Liu Zhengxin , Ma Jie
Published: September 2022

One of the most important issues in modern condensed matter physics is the realization of fractionalized excitations, such as the Majorana excitations in the Kitaev quantum spin liquid. The 3d-based Kitaev candidate Na2Co2TeO6 is promising to realize such kind of spin liquid phase under external magnetic fields. Here, we first established a complete phase diagram comprising an intermediate magnetically disordered phase sandwiched by the zigzag ordered phase and the polarized trivial phase by the in-plane magnetic torque measurements. Then, the observations, including the restoration of the crystalline point group symmetry in the angle-dependent torque data and the coexisting spinons and magnons from the inelastic neutron scattering data, provide strong evidence that this disordered phase is a field induced quantum spin liquid with partially polarized spins. Our variational Monte Carlo simulation with the effective K-J1-Γ-Γ′-J3 model agrees well with the experimental data and further supports this conclusion.