bluuebunny/crossref_metadata_2025 huggingface dataset:
Garantia de Preços Mínimos para Produtos da Sociobiodiversidade no Pará, Brasil
Authors: Mascarenhas Diego Fonseca , Paes Alberto de Moraes Papaléo , Farias Laurimar de Matos , Faria Tamara Lima Martins
Published: February 2025

RESUMO Objetivo: analisar as potencialidades e os desafios do desenvolvimento da Política de Garantia de Preços Mínimos para os Produtos da Sociobiodiversidade (PGPM-Bio) no contexto do Plano Estadual de Bioeconomia do Pará (PlanBio). Marco teórico: sob a perspectiva de Amartya Sen e sua obra Liberdade como desenvolvimento, busca-se analisar como a PGPM-Bio estabelece preços mínimos para produtos extrativistas e o desenvolvimento sustentável da região. Método: a pesquisa utiliza uma metodologia qualitativa, com base na triangulação de dados provenientes das legislações nacional e estadual relacionadas à bioeconomia, bem como de dados socioeconômicos e demográficos analisados à luz da teoria das capacidades de Amartya Sen. A análise dos dados foi realizada a partir de três construtos principais que emergiram da literatura: ‘políticas públicas’, ‘bioeconomia’ e ‘preços mínimos’. Resultados: a principal evidência aponta que a política de preços mínimos tem um impacto positivo na renda dos produtores extrativistas e comunidades tradicionais, contribuindo para a conservação da sociobiodiversidade e o desenvolvimento sustentável no estado do Pará. No entanto, também se antecipam desafios, como a necessidade de recursos financeiros mais robustos e o aprimoramento da política para garantir a efetividade das ações. Os resultados indicam que a PGPM-Bio, ao garantir preços mínimos para produtos extrativistas, contribui para a melhoria da renda e da qualidade de vida dos extrativistas, promovendo a segurança alimentar e a inclusão econômica. Conclusões: a pesquisa contribuirá para o desenvolvimento de políticas públicas mais eficazes e para o fortalecimento da bioeconomia na região, promovendo a inclusão social e a conservação ambiental.
Quando a professora brinca, aprende a ensinar as crianças a brincar? Experiências em processos formativos
Authors: Bersch Ângela Adriane Schmidt , Ribeiro Camila Borges , Finoqueto Leila Cristiane
Published: February 2025

RESUMO Objetivamos identificar a ressonância de vivências e experiências corporais na prática pedagógica de professoras atuantes na Educação Infantil a partir da participação em um curso de formação continuada. As participantes eram 30 professoras e os instrumentos utilizados foram diários de campo, memoriais descritivos, relatórios de feedback, imagens das experimentações das professoras com as crianças, a avaliação final e análise de conteúdo. As docentes não tinham clareza sobre como propor, de forma coesa e objetiva, estratégias e práticas educativas pela via corporal, entretanto, a formação continuada possibilitou a ressignificação das práticas pedagógicas no cotidiano da Educação Infantil.
Synopsis of Onagraceae (Myrtales) in the state of Santa Catarina, southern Brazil
Authors: Farias David Moura , Funez Luís Adriano , Gasper André Luís de
Published: February 2025

Abstract Onagraceae is a cosmopolitan family with 22 genera and about 660 species, most frequently found in subtropical and temperate regions. In Brazil, 64 species occur across four genera: Epilobium, Fuchsia, Ludwigia, and Oenothera. The family has been widely studied in terms of its anatomy, reproductive biology, taxonomy, and phylogeny; however, studies on Onagraceae in Santa Catarina are scarce, with no complete taxonomic review. Our objective was to review the Onagraceae family and to develop a synopsis of the species that occur in Santa Catarina. A bibliographic review was conducted, along with the analysis of exsiccates from the family collected in the state and deposited in the southern Brazilian herbaria CRI, FLOR, FURB, HBR, JOI, LUSC, and MBM. We identified 31 species, provided identification keys for the genera and species, and commented on each species.
Photobiomodulation on vocal training and rehabilitation: Delphi consensus based on experts
Authors: Pontes Emerson Soares , Vaiano Thays Garcia , Bastos Roberto Sávio de Assunção , Duarte João Marcos da Trindade , Santana Émile Rocha , Lopes Leonardo Wanderley
Published: February 2025

ABSTRACT Purpose To develop a consensus among speech-language pathologists who are voice specialists regarding the criteria for recommending and using photobiomodulation in the context of vocal therapy and training. Methods Seven speech-language pathologists, experts in voice, and with experience in using photobiomodulation in vocal therapy and training participated. The Delphi technique was used to achieve consensus from a panel of experts accessed independently in two phases of collection. In Phase 1, the experts were contacted individually and participated in an interview with 12 questions to gather opinions on the use of photobiomodulation in the investigated context. The experts' responses were used to construct a questionnaire with 55 items presented as statements. The experts were asked to analyze each item and indicate their level of agreement on a five-point Likert scale. The content validity coefficient (CVC) was used to investigate the degree of agreement among the judges and to select the final items of the consensus. Results Consensus was reached among the experts on 34 items investigated in this study, with a CVC ≥ 0.75. It was observed that 31 items achieved an excellent CVC (≥ 0.78), 14 items with a good CVC (0.60 ≥ CVC ≤ 0.77) and 10 items with a poor CVC (≤ 0.59). The total CVC was considered excellent, with a value of 0.78. Conclusion There was a consensus among experts about the use of photobiomodulation in vocal habilitation and rehabilitation. It has the potential to improve the criteria for prescribing and using this device by speech-language pathologists. The findings may be useful to improve the criteria for prescribing and the use of this device by speech-language pathologists, in addition to subsidizing the development of future research and clinical recommendations in the area.
Apresentação de um Protocolo de treinamento auditivo aplicado em crianças com Transtorno do Processamento Auditivo Central
Authors: Carvalho Nádia Giulian de , Pereira Mariana Venâncio Silveira , Colella-Santos Maria Francisca
Published: February 2025

RESUMO Objetivo Apresentar um protocolo de treinamento auditivo em crianças com Transtorno do Processamento Auditivo Central (TPAC). Método Participaram do estudo nove crianças entre 9 e 12 anos, sendo cinco do sexo feminino e quatro do sexo masculino. Foram selecionadas apenas crianças com limiares auditivos dentro da normalidade e curva timpanométrica tipo A bilateralmente. Inicialmente, foi realizada uma avaliação comportamental do Processamento Auditivo Central (PAC) e aplicado um questionário de autopercepção. Posteriormente, foram conduzidas oito sessões de treinamento auditivo, seguindo um protocolo definido com quatro atividades específicas por sessão, visando o treinamento de habilidades auditivas distintas. Em uma terceira fase, realizou-se nova avaliação comportamental do PAC e o questionário foi reaplicado. Resultados A análise quantitativa dos testes comportamentais pré e pós-treinamento mostrou melhorias estatisticamente significativas no Teste Dicótico de Dígitos (TDD) à esquerda, no Teste Dicótico de Dissílabos Alternados (SSW) à esquerda, no Teste de Identificação de Sentenças Sintéticas com Mensagem Competitiva Ipsilateral (SSI) à esquerda e no Teste de Detecção de Intervalo Aleatório (Random Gap Detection Test - RGDT). Observou-se também melhora na percepção comportamental auditiva dos participantes, conforme indicado pelas respostas ao questionário de autopercepção. Conclusão Apesar de o protocolo de treinamento auditivo não ter resultado na normalização completa nos testes de Avaliação Comportamental do Processamento Auditivo Central (PAC), observou-se uma contribuição na melhoria das habilidades auditivas de integração binaural, figura-fundo e resolução temporal dos participantes, bem como em sua percepção pessoal dessas capacidades.
DPOAE growth function in schoolchildren with impaired temporal ordering skills
Authors: Kumagai Patricia Kimiko , Sanches Seisse Gabriela Gandolfi , Carvallo Renata Mota Mamede
Published: February 2025

ABSTRACT Purpose To investigate whether the cochlear responses of a group of children with normal temporal ordering tests would be different from those children with abnormal results in the same tests. Methods 25 children aged 8 to 13 years participated in the study, all with normal range pure-tone audiometry thresholds, type A tympanometry and distortion product otoacoustic emissions (DPOAE) present in both ears. Of these, 13 children formed the Study Group and 12 the Control Group. The Study Group differed from the Control Group by presenting changes in temporal auditory tests. In addition to the tests to verify the inclusion criteria, the DPOAE growth function were recorded for three different f2 frequencies, respectively 2002, 3003 and 4004 Hz. The stimuli were presented at level f2 (L2) from 20 to 65 dB SPL in steps of 5 dB and the stimulus level f1 (L1) followed the formula: L1=0.4L2+39 dB. The data were analyzed statistically, adopting a significance level of 5%. Results The groups did not differ in relation to conventional DPOAE values (DP-Gram). The Study Group differed from the Control Group by exhibiting both the threshold (p=0.034) and the higher slope (p=0.043) in the 2000 Hz DPOAE growth. Conclusion Children with alterations in temporal ordering tests require greater intensity to reach the DPOAE threshold at a frequency of 2000 Hz when compared to children without complaints, also presenting a more linear cochlear amplification at this same frequency, indicated by the increase in the value of slope.
Relação entre risco de disfagia e nível de ingestão oral em pacientes oncológicos
Authors: Rocha Alexia Diovana Fernandes da , Berbert Monalise Costa Batista , Martins Vera Beatris
Published: February 2025

RESUMO Objetivo Relacionar o risco de disfagia autopercebido com o nível de ingestão oral em pacientes oncológicos hospitalizados. Método Estudo transversal, com amostra por conveniência composta por indivíduos adultos e idosos, com diagnóstico de câncer e internados em um hospital oncológico do sul do Brasil. Os dados sobre sexo, idade, tempo de internação, comorbidades, diagnóstico oncológico, tratamento e via de alimentação, foram obtidos dos prontuários dos participantes. O nível de ingestão oral foi classificado pela Functional Oral Intake Scale (FOIS), o risco de disfagia foi identificado pelo Eating Assessment Tool (EAT-10) e a relação entre eles foi feita por meio do coeficiente de correlação de Spearman. Resultados Foram incluídos 60 participantes (42 tumores sólidos e 18 tumores hematológicos), sendo 35 do sexo feminino (58,3%) e 25 do sexo masculino (41,7%), com média de idade de 58,5 ± 13,1 anos. Destes, 56 se alimentavam por via oral exclusiva (93,3%) e 18 apresentavam risco de disfagia (30%). Os idosos apresentaram maior risco para disfagia em comparação aos adultos (p-valor = 0,020). A relação entre a pontuação do EAT-10 (mediana 0; IQR = 0 - 4) e a classificação da FOIS (N: nível 2 = 2; nível 3 = 2; nível 4 = 2; nível 5 = 12; nível 7 = 42) demonstrou correlação inversa significativa (RHO = -0,463; p-valor = 0,000). Conclusão Observou-se que quanto menor a pontuação no EAT-10, maior o nível da FOIS. Ou seja, quanto menor o risco para disfagia, menor a suscetibilidade ao uso de via alternativa de alimentação.
Políticas de Saúde dos Estados Brasileiros Durante a Pandemia de Covid-19: Um Dataset das Normativas Produzidas
Authors: Fernandez Michelle , Bertholini Frederico , Maia Bárbara
Published: February 2025

Resumo Este banco de dados apresenta um amplo panorama das normativas de saúde elaboradas pelos governos estaduais do Brasil durante a evolução da pandemia de Covid-19. Para sua consolidação, reunimos e analisamos os marcos regulatórios de políticas de saúde desenvolvidas pelos 27 estados do Brasil no período de fevereiro de 2020 a outubro de 2021, abrangendo as três primeiras ondas da Covid-19 no país. Temos como resultado um conjunto original de dados de Regulação Subnacional, compreendendo mais de 4 mil normas relacionadas à Covid-19 no campo da saúde. Esse banco de dados visa contribuir para o entendimento das respostas estaduais à pandemia, considerando o contexto federativo e a autonomia das autoridades locais.
Os Fluxos de Comunicação Digital nas Instituições Públicas: A Institucionalização e a Instrumentalização a partir da Percepção dos Produtores de Conteúdo das Câmaras Municipais*
Authors: Massuchin Michele Goulart , Oliveira Paula Andressa de
Published: February 2025

Resumo A comunicação legislativa é eficiente quando provoca novos comportamentos políticos e estreitamento da relação dos representantes com a sociedade (Leston-Bandeira, 2012). Por conta disso, instituições públicas têm ocupado o ambiente digital não somente pelas exigências da legislação, mas, também, por iniciativas próprias visando a visibilidade, transparência, prestação de contas e proximidade com os cidadãos. Neste cenário, a prática da comunicação pública de caráter institucional perpassa por novas dinâmicas, especialmente pelas características dos diferentes poderes. Assim, este artigo busca compreender — com base na percepção de agentes do campo — que variáveis interferem na comunicação institucional dos legislativos municipais, caracterizados por menor infraestrutura, pessoal reduzido, baixa institucionalização dos fluxos informativos e que, por natureza, são marcados pela proximidade com os cidadãos. Por meio de entrevistas semiestruturadas, tendo como foco dez assessores responsáveis pela comunicação dos parlamentos locais do Paraná, percebe-se cinco questões que se manifestam: desinteresse dos gestores, exigências profissionais, limites e “medos” na produção das mensagens, interesses político-partidários e entraves no relacionamento com o público. De forma ampla, a comunicação digital das Câmaras Municipais transita entre a institucionalização e instrumentalização dos fluxos informativos.
Macro-Regional Disparities in Specialized Dental Care for Children in the Brazilian Unified Health System: An Ecological Study
Authors: Lima Ricardo Barbosa , Moura Ana Paula Gomes e , Aguiar Débora Amorim Alves de , Nelson-Filho Paulo , Silva Léa Assed Bezerra da , Silva Raquel Assed Bezerra da
Published: February 2025

ABSTRACT Objective: To investigate macro-regional disparities in specialized outpatient dental care for children in the Brazilian Unified Health System (SUS). Material and Methods: An ecological study was conducted using a longitudinal, retrospective, and quantitative approach. The number of outpatient dental procedures (ODPs) performed by Pediatric Dentists in the SUS was retrieved by the Outpatient Information System (SIA/SUS), considering the period between 2008 and 2022, as well as the five macro-regions of Brazil. Statistical analysis was based on descriptive and analytical approaches. The significance level was adjusted to 5%. Results: More than 29 million outpatient dental procedures were performed in the last 15 years by Pediatric Dentists in the SUS. The incidence rate of ODPs was significantly lower in the Northeast macro-region compared to the other macro-regions and the national estimate (p<0.05). The north was the only macro-region that showed a decreasing temporal trend over the last 15 years (p=0.026), while the others were stationary (p>0.05). However, when the COVID-19 pandemic years were removed, testing from 2008 to 2019, the trend was also stationary (p=0.351). In addition, the North macro-region was the only one not correlated with the national estimate (p=0.478), showing a distinct pattern in the incidence rate of ODPs over the last 15 years. Nonetheless, The variability of this particular variable was striking across all macro-regions, but it was especially pronounced in the north. Conclusion: There are macro-regional disparities in specialized dental care for children in the Brazilian Unified Health System.
Addressing under-registration in Chagas disease mortality: insights from the SaMi-Trop and REDS cohorts
Authors: Bierrenbach Ana Luiza , Oliveira Claudia Di Lorenzo , Quintino Nayara Dornela , Baldoni Nayara Ragi , Moreira Carlos Henrique Valente , Ferreira Ariela Mota , Silva Lea Campos de Oliveira da , Oikawa Márcio , Nunes Maria do Carmo Pereira , Cardoso Clareci Silva , Haikal Desirée Sant’Ana , Ghilardi Fabio de Rose , Vieira Thallyta Maria , Ribeiro Antonio Luiz Pinho , Sabino Ester Cerdeira
Published: February 2025

ABSTRACT Chagas disease (ChD) remains a significant public health concern in the Americas, with challenges to accurately assessing its mortality burden due to under-reporting and misclassification. This study aimed to analyze mortality patterns of two cohorts of individuals with ChD—one comprising asymptomatic individuals with positive serology (REDS) and another with patients showing Chagas cardiomyopathy (SaMi-Trop)—to propose a method for estimating the potential under-registration of Chagas-related deaths and to find the factors influencing the identification of ChD as the underlying cause of death. We carried out a retrospective analysis of mortality data from these cohorts together with data on the Brazilian Mortality Information System. Causes of death were classified according to ICD-10 codes, and an expert review was used to find possible Chagas-related deaths. Logistic regression was used to explore predictors of ChD identification considering demographic and clinical variables. Of 2,488 patients, 381 died, 28.9% attributed to ChD, predominantly chronic ChD with cardiac involvement (B57.2). Using our method, we estimated a 53.8% potential under-registration rate for possible Chagas deaths. Males were negatively associated with Chagas disease identification, with an odds ratio of 0.52 (95%CI 0.24–1.1). No other significant associations were found, and the overall significance of the model was low. Our findings provide a potential measurement of under-registration, indicating that it may be substantial. These results underscore the need for improved identification and accurate reporting on death certificates. Strengthening the quality of mortality data is essential to understand Chagas-related mortality and guide public health strategies to reduce its impact.
Environmental heterogeneity in wetlands increases alpha and beta diversity of cladocerans (Crustacea, Branchiopoda) at local and regional scale
Authors: Sousa Francisco Diogo Rocha , Elmoor-Loureiro Lourdes Maria Abdu , Mendonça-Galvão Luciana , Simões Nadson Ressyé
Published: February 2025

Abstract: Aim The goal of this study was to investigate the effect of habitat heterogeneity on diversity on a local and regional scale. We tested two hypotheses: (i) the habitat diversity, given by quantity of microhabitat by macrophytes richness, increases the alpha diversity of organisms that live in those environments; (ii) the habitat heterogeneity, given by compositional difference of microhabitat, increases the beta diversity of organisms that live in those environments. Methods Samples contained cladocerans and macrophytes were collected in six wetlands from the Brazil Central during dry and rainy seasons, in Brazilian National Park (BNP) and Formosa Instruction Field (FIF). Results In local scale (wetlands) the number of macrophyte morphospecies shows the positive effect on alpha diversity of cladoceran; the compositional difference of the microhabitat positively affected the beta diversity in three wetlands studied. In regional scale, the number of macrophyte morphospecies showed the positive effect on alpha diversity; the beta diversity was higher in the BNP than in the FIF. Conclusions Our findings suggest that the species richness and dissimilarity of aquatic macrophytes increased to alpha and beta diversity of cladocerans on the local and regional scales. Thus, cladocerans richness was correlated with the number of microhabitats and the variability between microhabitats in wetlands.
3D Printable Ca(OH)2-based geopolymer concrete with steel fiber reinforcement
Authors: Mortada Youssef , Hammoud Ahmad , Masoud Laith , Wyrzykowski Mateusz , Sirtoli Davide , Lura Pietro , Mansoor Bilal , Masad Eyad
Published: February 2025

This study investigates the impact of varying steel fiber (SF) content (0%, 0.8%, 1.0%, and 1.2% by volume) on the mechanical and durability properties of 3D-printed Ca(OH)2-activated geopolymer concrete (GPC). The addition of 1.2% SF improved flexural strength by 69% at 7 days and 16% at 28 days, while tensile strength more than doubled to 3.75 MPa at 28 days. Although compressive strength remained unaffected at 43 MPa, SF enhanced interlayer bond strength by 20%, which is crucial for layer cohesion in 3D-printed structures. Additionally, the elastic modulus increased by 7%, contributing to improved stiffness. Durability assessments, including autogenous shrinkage and self-induced stress, indicated a slight reduction in shrinkage of SF-reinforced samples, with no significant effect on self-induced stress. Microstructural analysis using scanning electron microscopy (SEM) and X-ray micro-computed tomography (µCT) demonstrated the crack-bridging behavior of steel fibers, enhancing ductility and fracture resistance. There was a slight increase in porosity (5.34%) of SF-reinforced samples without negatively affecting their mechanical properties. Notably, SF improved early-age toughness and controlled crack propagation across printed layers, addressing a critical challenge in 3D-printed concrete. The novelty of this work lies in successfully reinforcing 3D-printed Ca(OH)2-activated GPC with recycled steel fibers, enhancing mechanical properties, interlayer bonding, and durability without compromising printability. This study offers a sustainable reinforcement strategy for 3D printing in construction.
Modern concepts of preeclampsia, taking into account the role of the permeability of the hematoencephalic barrier
Authors: Sidorova I.S. , Managadze I.D.
Published: February 2025

The article presents modern data from the world literature on the nature and essence of preeclampsia as a general pathological specific gestational endotheliosis, the leading role in the pathogenesis of which is played by damage to the endothelium with a change in the functional properties of the blood-brain barrier (BBB) — a violation of its integrity and permeability, including in combination with damage to neurons and glia. An important pathogenetic role of inadequate autoregulation and pathological changes in cerebral perfusion pressure in combination with impaired BBB permeability, leading to vasogenic cerebral edema and eclamptic seizures, has been revealed. A comparative analysis of a large number of clinical observations, general data and special research methods has significantly expanded the understanding of preeclampsia, taking into account the key role of BBB permeability in its development. The purpose of this review is to highlight exactly how the vascular function of the brain and the integrity of the BBB are disrupted in preeclampsia, which makes it possible to improve understanding of the effect of preeclampsia on the brain. New data on the role of the functional properties of BBB open up a different view on the unresolved issues of preeclampsia, allowing us to reconsider the therapeutic possibilities of managing patients with preeclampsia, taking into account the nature of brain damage.
Evolution of surgical methods for correction of pelvic organ prolapse
Authors: Tugushev M.T. , Nikonova M.A.
Published: February 2025

The problem of pelvic organ prolapse (POP) has a thousand-year history and still remains unresolved to the end. To find the optimal treatment for patients with POP, many different methods have been proposed, which are considered in this review. Their knowledge will help modern doctors, taking into account the experience of their predecessors, optimize the technique of surgical correction of POP, avoiding the mistakes of previous years, and develop new, modern technologies. We conducted a literature search in English and German using the keywords «pelvic organ prolapse», «anterior and posterior colporrhaphy», «cystocele» and «interposition operations» in the PubMed database. Other relevant articles in journals and textbooks are found by searching for references cited in previous articles and textbooks.
Dictionnaires et corpus numériques pour l’enseignement du FLE : un parcours didactique sur le lexique
Authors: Faresin Francesco
Published: February 2025

Cet article se concentre sur l’exploration du rôle des dictionnaires collaboratifs (Wiktionnaire, Dictionnaire des francophones et Bob) et des bases de traitement de corpus (Lexicoscope et Compleat Lexical Tutor) dans l’enseignement du FLE, en mettant particulièrement l’accent sur l’enseignement des unités phraséologiques. À travers une série d’exercices et d’activités didactiques, l’article propose une démarche pédagogique pour intégrer efficacement ces ressources numériques dans la salle de classe de FLE, tout en développant les compétences linguistiques des apprenants. Enfin, l’article présente les résultats d’une évaluation auprès d’un groupe d’enseignants, mettant en lumière leurs perspectives sur l’intégration des dictionnaires collaboratifs dans l’enseignement de FLE. Ces résultats soulignent la nécessité d’une formation continue des enseignants et d’une planification pédagogique attentive pour tirer pleinement profit du potentiel de ces outils.
Les enjeux d’un cadre de référence en ligne pour le corse
Authors: Sorba Nicolas , Di Meglio Alain
Published: February 2025

À travers l’évaluation des enjeux concernant un projet de création d’un cadre de référence linguistique, cet article traite de la situation actuelle de la langue corse et de ses défis en matière d’équipement, d’élaboration et de reconnaissance. Il souligne que l’usage du corse a évolué ces dernières années et a connu une diversification de ses pratiques. Le texte mentionne également la nécessité d’une description et d’un recensement des termes et expressions nouvelles utilisés dans de nouveaux domaines (médias, politique et école notamment) ainsi que la question la question, plus générale, de la revitalisation linguistique. Le projet porté par l’UMR CNRS 6240 LISA, de l’Université de Corse, et qui est l’objet principal de l’article, tente de répondre à toutes ces problématiques.
Commentary: Workplace based rehabilitation for upper limb conditions in the South African context
Authors: Hoosain Munira , De Klerk Susan , Burger Marlette
Published: February 2025

Workplace-based rehabilitation is a growing field of practice internationally and locally. This commentary discusses the current barriers and facilitators facing South African occupational therapists wanting to implement workplace-based rehabilitation with upper limb conditions. An overview is provided of current international practice in the field and relevant factors in the South African context. Recommendations are made for development in this field in clinical practice, research and education in South Africa.
Key words: Workplace-based rehabilitation, occupational health, upper limb, workplace health, disability
Organización, gestión y gobierno de la UPS (enfoque cuantitativo)
Authors:   Universidad Politécnica Salesiana, Cárdenas Tapia Juan Alcides
Published: February 2025

Para comenzar, presentamos un perfil de la población (156 docentes) a la que se aplicó la encuesta en el año 2014 (cf. anexo 1). Se clasificó la población según cuatro criterios importantes para el análisis: por sedes a las que pertenecen, por años de servicio a la UPS, por tiempo de dedicación y por categoría en el escalafón.
Mouse Embryonic Stem Cells Culture and Differentiation to Neural Stem Cells v1
Authors: Anand Abhinav , Bustos Francisco
Published: February 2025

The property of stem cell pluripotency observed in the inner cell mass of the developing mouse embryo at the blastocyst stage can be modeled in vitro via mouse embryonic stem cells (mESCs). mESCs can be cultured in gelatinized plates with media containing Leukemia inhibitory factor (LIF) and fetal bovine serum (LIF and serum), which maintains a dynamic and heterogeneous pluripotency state. These cells can also be cultured in media with two kinase inhibitors (2i) + LIF, which maintains a homogeneous naive pluripotent state that is germline competent. These cells can be differentiated to the neural lineage by culturing them in neural stem cell (NSC) media, and NSCs can be isolated and cultured from this process. Here we describe protocols for culturing mESCs in LIF and serum or 2i + LIF conditions, and induction of neural differentiation to obtain and culture mESC-derived mouse NSCs.
Ancient DNA Extraction from Bones and Teeth v1
Authors: V. Westbury Michael , Rey-Iglesia Alba , A. Cabrera Andrea , Li Vanssy , de Jager Deon , D. Lorenzen Eline
Published: February 2025

Ancient DNA Extraction Protocol (spin column-based) This protocol outlines the procedure for extracting ancient DNA from bone or tooth powder using Monarch spin columns. The final DNA extract volume will be 35 µL. Based on: The spin column protocol is based on Dabney et al. 2013 (DOI:10.1073/pnas.1314445110) The modified binding buffer is from Allentoft et al. 2015 extraction (DOI: 10.1038/nature14507) Protocol initially written up by Michael V. Westbury on 20-08-2018. Annotations added by Andrea A. Cabrera and Alba Rey-Iglesia on 08-11-2019. The procotols.io version was created by Wenxi Li and Deon de Jager.
Regarding the use of Adrenaline solution in surgery (combustiology) for skin burns: a literature review
Authors: Yurova Yulia V. , Zinoviev Evgeny V. , Krylov Pavel K. , Pankratieva Olga S. , Talalaev Kirill M.
Published: February 2025

Based on the analysis of the literature and our own experience, the data on the use of adrenaline 0.1% solution as a vasoconstrictor for topical application during surgical treatment of burned patients are systematized. In surgery-combustiology, adrenaline is used in the following clinical cases: subcutaneous administration for hemostasis of the donor site after graft taking by dermatome;subcutaneous injection of the drug under necrotic tissues for hemostasis in necrectomies; local applications of bandages with adrenaline solution in diffuse bleeding. In the literature there is information about the hemostatic effect of adrenaline with its subcutaneous administration. It is important to remember that the maximum permissible single dose of adrenaline for adults with subcutaneous injection is 1 ml. Complications with the use of this drug can include a list of serious nosologies, up to the development of tissue necrosis, heart rhythm disturbances, lethal outcome. It is believed that the leading cause of such complications is the systemic action of the drug, incorrect calculation of the drug dose, peculiarities of the general condition of the body, concomitant use of a number of drugs, in particular narcotic analgesics. Vasoconstrictor effect of adrenaline leads to prolonged tissue ischemia, local use of anesthetic drugs together with adrenaline can lead to ischemia and necrosis of distal parts of the extremities, in particular fingers. A significant impact on the incidence of complications during adrenaline administration is caused by conditions associated with blood coagulation disorders, liver diseases, coagulopathies of various genesis, vascular changes. When using adrenaline solution it is necessary to intraoperatively monitor blood pressure and pulse. In case of tachycardia and increased pressure, it is necessary to suspend the use of the drug without waiting for the development of serious consequences. Specialists proposed the calculation of the volume of 0.9% sodium chloride solution with adrenaline in the preparation of the donor site before the skin split graft, the excess of which can lead to general complications. 2500 mL is the maximum amount of saline solution when administered at 2 drops of adrenaline per 250 mL when the preparation is administered subcutaneously. There is no unanimous opinion among combustiologists about indications and contraindications, dosage calculation, methods of administration, probability of complications development.
Stimulation of the epicardium as a source of myocardial repair: from experiment to clinical practice
Authors: Timofeev Eugene V. , Bulavko Yana E.
Published: February 2025

Mortality from myocardial infarction and its complications — heart rhythm disturbances, myocardial remodeling with subsequent development of congestive heart failure — occupies a leading place in the world. Activation of the epicardium is being actively studied as one of the ways to prevent cardiac remodeling. The method is based on the ability of embryonic epicardial cells to undergo epithelial-mesenchymal transformation, as a result of which the resulting epicardial-derived cells give rise to various cytological lines — cardiac fibroblasts, smooth muscle cells of the vascular wall, adipocytes and cardiomyocytes. In the postnatal period, this regenerative potential is absent. Currently, various methods have been developed to activate the reparative potential of the epicardium using options for genetic reprogramming of epicardial cells using viral vectors, exposure to paracrine factors involved in the formation of the heart and its structures — transcription factors GATA4, GATA6, thymosin-β4, introduction of embryonic stem cells or induced pluripotent stem cells in tissue-engineered constructs, activation of fibroblast growth factors ( FGF ), and platelet-derived growth factor ( PDGF ). These methods are being actively studied in experimental models of myocardial infarction and have shown their high efficiency in vitro. The results of transplantation of tissue-engineered structures during coronary artery bypass surgery in patients with severe post-infarction heart failure show promise in terms of slowing down myocardial remodeling.
Fortalecimiento de las capacidades empresariales en cadenas productivas de gastronomía y moda en Colombia
Authors: Peñaranda Delgado Lina , Acacio Navarro José
Published: February 2025

This article presents the results of a research project in which Gastronomy and Fashion companies that contribute to the economy grow in Colombia have participated, but hey also have deficiencies that came through social issues and low access to knowledge, and therefore in innovation for competitiveness, highlighting the nature of their business structure as they are mostly family businesses made up of natural persons with a poorly structured model in planning and management necessary for the transformation towards more favorable market scenarios, in addition to the dependence on a few partners business, and the economic contraction caused by the Covid-19 pandemic, as well as some national protests in recent years by some social groups. In order to demonstrate opportunities for improvement and transform some of the difficulties into strengths, the project is part of a strategic alliance between the Cámara de Comercio de Bucaramanga and the Unidades Tecnológicas de Santander as a higher education institute, to promote the development of activities for entrepreneurs and strengthen their business skills in marketing, integrating the academy with the business sector from research and extension. This project has been developed in 3 phases: 1. Characterization of the business communities that voluntarily joined the project. 2. Strengthening of business skills with workshops aimed by detecting needs and formulation of strategic action plans mediated by innovation. 3. Follow-up in the implementation of proposed actions contributing to knowledge management. Entrepreneurs are enabled to renew improvements, making the development of brands sustainable through the practice of acquired knowledge.
Embolismo pulmonar y trombosis venosa profunda: aspectos clínicos y terapéuticos
Authors: Merchán-Galvis Angela Maria , Obando-Valencia Cristian Reinaldo , Tobar-Diaz Jorge Felipe
Published: February 2025

Introduction: venous thromboembolism encompasses deep vein thrombosis and pulmonary embolism; It represents the third most important vascular disease, causing high potentially preventable morbidity and mortality. Treatment focuses on early anticoagulation to prevent complications, but that does not always restore venous patency. In this scenario, thrombolysis is an option, especially in patients with significant hemodynamic compromise or with involvement of high-risk anatomical segments; However, those who are not candidates to receive thrombolytics pose a greater challenge.
Objective: to present the clinical, diagnostic, and therapeutic characteristics, emphasizing the endovascular options available, describing their techniques and indications, highlighting their benefits and safety to treat patients with venous thromboembolism.
Methods: narrative review based on the bibliographic search in the PubMed and Scielo databases.
Conclusion: This review highlights endovascular management techniques for venous thromboembolism compared to classic thrombolytic therapy, especially in patients with high risk of bleeding; as well as in those who are contraindicated with systemic thrombolytics such as new oral anticoagulants due to hemodynamic compromise. Among the options available for endovascular therapy are catheter-directed thrombolysis and cutaneous embolectomy, which have lower rates of recurrence and complications after their application, highlighting that the choice must be individualized for each patient.
Impact of telemedicine mobile units on health outcomes, healthcare system resilience, and disaster response in flood-affected areas: a case study of Sehat Kahani
Authors: Khuld Hamna
Published: February 2025

Introduction: The study explores the deployment of telemedicine services. Sehat Kahani introduced a two-tier telehealth model combining physical camps, mobile units, and a telehealth app to enhance healthcare accessibility and delivery in crisis.
Objective: To assess the effectiveness of Sehat Kahani's telemedicine model in improving healthcare outcomes and system resilience. It also aims to identify key factors contributing to the successful integration of telehealth during flood emergencies.
Methods: Semi-structured interviews were conducted with key stakeholders: Sehat Kahani staff, healthcare providers, beneficiaries, funders, and top-level management. Interviews provided insights into the implementation process, challenges encountered, and strategies to address these challenges. We identified themes related to resource analysis, accessibility, security, scalability, training, evaluation, collaboration, and sustainability.
Results: The findings underscore the significance of comprehensive assessments, budget analysis, and collaboration with government agencies and corporate partners in successfully implementing telehealth services. Accessibility was effectively addressed through Sehat Kahani's multi-tiered model, which combined mobile clinics with a user-friendly telehealth app. Security, privacy, and confidentiality were maintained by adhering to data protection regulations (HIPAA). Training programs for healthcare professionals focused on empathy, rapport building, and technical proficiency. Sehat Kahani's scalability measures and preparedness for increased patient volume facilitated efficient service delivery during disasters.
Conclusions: Sehat Kahani's comprehensive approach, encompassing resource analysis, accessibility, security, scalability, training, evaluation, collaboration, and sustainability, successfully integrates telehealth into disaster relief efforts. This model offers valuable insights for future telehealth initiatives in disaster response scenarios, particularly in developing nations affected by flood emergencies.
A institucionalização de métricas de impacto social: O caso da Unifesp
Authors: Brelaz Gabriela de , Meister Izabel Patrícia , Palmeira Júnior Vanderlin Amorim , Brandão Guilherme Sydow Nunes Bueno , Silva Lidiane Cristina da , Carvalho Alexsandro Cardoso
Published: February 2025

Este artigo apresenta um framework para institucionalização de métricas de impacto social (MIS) para a Universidade Federal de São Paulo (Unifesp) baseado nos Objetivos de Desenvolvimento Sustentável (ODS) da Organização das Nações Unidas (ONU). Fundamenta-se no institucionalismo sociológico e na dinâmica do ranking Times Higher Education (THE), bem como articula as políticas universitárias com os ODS e alinha as atividades de ensino, pesquisa, extensão e cultura como interface dialógica com a sociedade. Os métodos de design, de design science research e dos pilares analíticos de Scott (regulativo, normativo e cultural-cognitivo) são utilizados. Como resultado, foi desenvolvido um framework MIS-Unifesp que estabelece princípios de análise institucional pautados em métricas.
An Investigation into Peer-Assisted Learning in an Online Lab Environment
Authors: Li Rui , Morelock John R. , May Dominik
Published: February 2025

Peer learning is one method to encourage meaningful learning in electrical engineering courses. It involves the sharing of ideas, knowledge, and experiences and emphasizes interpersonal learning. However, there are different viewpoints in relation to the best way to implement and assess peer learning in a lab environment, and contemporary literature on online laboratories (OL) rarely explores peer learning opportunities. In this paper, we aim to investigate the benefits of students' peer learning activity in an online electronics lab course. The key challenge was whether the OL could ensure smooth communication and collaboration between the students. In our case, we applied Zoom online conferencing software as a communication tool and LabsLand as an interactive OL tool. Specifically, we used a remote lab application for electrical circuit building, which makes physically existing lab infrastructure remotely usable through an online user interface. Methods we used to assess our learning outcomes included online surveys, online lab usage, and lab report scores. The survey results showed there are positive opinions about component skill development from group lab activities. In an online lab, the tasks were divided based on team members' strengths. In terms of peer learning, some students felt there was an improvement in partners' skills in terms of the circuit assembly. The OL usage showed a high level of engagement in group activity. Students willingly spent more time on lab experiments beyond regular lab hours. The scores of lab reports showed this new way of peer learning could achieve learning outcomes comparable to conventional, physical labs using peer learning. Accordingly, we concluded that the OL was an alternative and effective way to encourage peer learning.
V Simposio Internacional por el Día Mundial del Suelo
Authors: Mario Caviedes Galo , Albán María Gabriela , Moreno Víctor Julio
Published: February 2025

La Unión Internacional de las Ciencias del Suelo (IUSS) recomendó una jornada internacional para homenajear al suelo en 2002. Ante este pronunciamiento la Asamblea General de la ONU designó el 5 de diciembre de 2014 como el Primer día Mundial del Suelo. Desde esta fecha, el día Mundial del Suelo se celebra anualmente con la finalidad de sensibilizar a la población y entes de Gobierno sobre la importancia de un suelo sano y abogar por la gestión sostenible de este recurso.
La Alianza Mundial por el Suelo (AMS) de la Organización de las Naciones Unidas para la Alimentación y Agricultura (FAO), tiene la finalidad de aplicar las disposiciones de la Carta Mundial de los Suelos de 1982 y concientizar a los encargados de la toma de decisiones sobre la importancia de los mismos para la seguridad alimentaria, la adaptación al cambio climático y la mitigación de sus efectos.
La representación del Ecuador ante la Alianza Mundial por el Suelo (AMS) de la Organización de las Naciones Unidas para la Alimentación y Agricultura (FAO), trabaja para mantener la fertilidad y productividad de los suelos, promoviendo el cuidado del suelo de amenazas continuas como la erosión, compactación, acidificación, contaminación, salinización, anegamiento, desequilibrio de nutrientes, pérdida de materia orgánica y biodiversidad.
Concepts of Economic and Cultural Types and Historical and Cultural Areas: Contribution of Soviet Ethnography to Cultural-Geographical Regionalisation
Authors:  Yamskov A.
Published: February 2025

Aim. We analyze the emergence and development of interrelated concepts of economic and cultural types and historical and cultural areas in Soviet ethnography and related fields of American cultural anthropology of the 20th century. A review is presented of the development of interpretations of these terms. A number of regionalisation schemes based on these concepts are critically analyzed and some of the problems and prospects for the possible use of these concepts in historical and cultural geography are assessed.

Methodology. This work is historiographical in nature, and is based on the analysis of the most important publications in the studied fields of domestic ethnography and, in parts, American cultural anthropology.

Results. Some flaws in existing schemes of regionalisation of Eurasia, based on these concepts, are noted; the antecedents of the emergence of these concepts in Soviet ethnography and similarities or differences with the schools of “cultural ecology” and “culture areas” in American cultural anthropology are clarified.

Research implications. The prospects for applying the concepts of economic and cultural types and historical and cultural areas in cultural geography and regional studies are identified; proposals for modifying the terms used to denote these concepts are developed further.
Socio-Ecological Actors of the Evolution of Green Spaces of Tyumen
Authors: Fedorov R. Yu.
Published: February 2025

Aim. Reconstruction and analysis of the evolution of socio-ecological factors of the formation of green spaces of the Siberian city on the example of Tyumen.Methodology. The historical ecology of the city has been studied by actor’s approach. It means that some intellectual ideas, urban planning standards, institutional and informal communities of people may be considered as actors that shaped the green spaces of the city. At the same time, in the process of their development, certain elements of green spaces begin to play the role of natural actors that affect social behaviour and quality of people’s life.Results. A reconstruction of the socio-ecological aspects of the main stages of green spaces formation in Tyumen in the period from the 19th to the beginning of the 21th century was undertaken. The influence of social actors on the principles of the formation and reproduction of green spaces has been identified and analyzed.Research implications. The study formulated heuristic capabilities of the actor approach in the studies of socio-ecological interactions in green urban spaces. Retrospective study of the evolution of the development of urban socio-natural complexes from the standpoint of historical ecology makes deeper understanding the utilitarian and cultural significance of different elements of green spaces, as well as take into account the positive and negative experience of their creation in the modern practice of green infrastructure development in the city.