bluuebunny/crossref_metadata_2025 huggingface dataset:
Polyvinyl alcohol improves resistance of epoxy-treated bovine pericardium to calcification in vitro
Authors: Kostyunin A. E. , Rezvova M. A. , Glushkova T. V. , Shishkova D. K. , Kutikhin A. G. , Akentieva T. N. , Ovcharenko E. A.
Published: March 2023

Background. Around half of bioprosthetic heart valves become dysfunctional 15 years postimplantation because of structural valve deterioration notable for the degradation and calcification of the prosthetic tissue. Protection of bioprosthetic heart valves from structural valve deterioration requires innovative materials, science approaches including enveloping of the bioprosthetic heart valves into the polymer sheath.Aim. To develop a polyvinyl alcohol sheath for improving resistance of bioprosthetic heart valves to calcification.Material and methods. Bovine pericardium fixed with ethylene glycol diglycidyl ether was incubated with distinct concentrations of polyvinyl alcohol (5, 10, 12, or 15%) with the following freezing and thawing to perform cryotropic gelation. Surface and structure of unmodified and polyvinyl alcohol-modified bovine pericardium have been investigated by fluorescence microscopy and scanning electron microscopy, whilst tensile testing was carried out by uniaxial tension test. Haemocompatibility was assessed through the measurements of haemolysis and platelet aggregation/adhesion upon the contact of donor blood with the samples. Resistance to calcification was tested by incubation of the samples in calcium and phosphate supersaturated (10 µmol/L) cell culture medium for 3 and 6 weeks with the following tissue lysis and colorimetric measurement of Ca2+ ions.Results. Using cryotropic gelation, we obtained a polyvinyl alcohol-coated and filled bovine pericardium matrix. Out of all polyvinyl alcohol concentrations, 12% polyvinyl alcohol solution sealed pores and hollows within the bovine pericardium (what was not achieved using 5% or 10% polyvinyl alcohol solutions) and demonstrated the best processability as compared to 15% polyvinyl alcohol solution. Cryotropic gelation did not deteriorate durability, elasticity, or haemocompatibility of bovine pericardium. After 3 and 6 weeks of the incubation in calcium-supersaturated solution, polyvinyl alcoholmodified bovine pericardium contained 5- and 3-fold reduced amount of calcium compared to unmodified bovine pericardium.Conclusions. Enveloping of bovine pericardium into polyvinyl alcohol increases its calcification resistance, retains its tensile properties and haemocompatibility, and can be considered as a promising approach for the modification of bovine pericardium during the manufacturing of bioprosthetic heart valves.
Giant postinfarction posterolateral left ventricular aneurysm, complicated by mitral insufficiency
Authors: Bikbova N. M. , Mazanov M. Kh. , Sagirov M. A. , Kharitonova N. I. , Baranov A. A. , Argir I. A. , Mingalimova I. R. , Kambarov S. Yu.
Published: March 2023

Ischemic heart disease holds the leading position in the structure of cardiovascular diseases. Early reperfusion therapy for acute myocardial infarction led to a decrease in mortality and severe complications of coronary artery disease. Despite advances in the treatment of coronary artery disease, dilatation and remodeling of the left ventricle develop in 20% of patients who have had a heart attack, leading to mitral insufficiency and systolic dysfunction of the left ventricle. Aneurysm of the left ventricle is a delayed severe complication of myocardial infarction, which significantly worsens the prognosis. Large aneurysms of the left ventricle cause progressive dilatation of the left ventricle, its volumetric overload with an increase in wall tension in the non-infarction zone, decreased functional characteristics of the left ventricle, thrombosis in the aneurysm cavity, life-threatening arrhythmias, and sudden death. Postinfarction left ventricular remodeling can lead to secondary mitral regurgitation, which is an independent predictor of mortality in the longterm period. Surgical treatment of coronary heart disease and its complications is one of the main problems of modern cardiovascular surgery.
Issues of preparation for implementing uterine transplantation in clinical practice
Authors: Polstianoy A. M. , Gubarev K. K. , Polstianaya O. Yu. , Rendashkin I. V.
Published: March 2023

The absolute uterine factor infertility is a non-treatable cause of female infertility. Surrogacy has become the only option that allows this group of patients to achieve genetic, although biological motherhood. According to statistics there are more than 30 thousand women of fertile age in Russia who cannot get pregnant due to the absolute uterine factor infertility. The recently emerged possibility of uterine transplantation has become the only treatment for this kind of female infertility.Prior to the very first clinical study of human uterine transplantation which was carried out in 2013 in Sweden, scientists had conducted systematic studies in animals (rodents, pigs, cattle and primates). The first clinical trial with the uterine transplantation performed resulted in a live birth in September 2014. Currently, cases of successful uterine transplantation in humans have been reported in Sweden, Brazil, USA and Italy. Experience and practice in animal research played a key role in the success of the first clinical study on uterine transplantation. The application of this method is fundamental in the introduction of the scientifically grounded technology of uterine transplantation in Russia.Aim. Analysis of the problems of the clinical application of the uterine transplantation based on a literature review.
Immune mechanisms in the pathogenesis of acute peritonitis G.V. Bulava
Authors: Bulava G. V.
Published: March 2023

Acute inflammation of the peritoneum – peritonitis – often develops after injury to hollow visceral organs, intestinal necrosis, failure of anastomosis, or tumor processes. Subsequent microbial contamination of the abdominal cavity leads to infection, in response to which immune mechanisms are activated. The pathogenesis of inflammatory processes in the abdominal cavity and their features are largely determined by the structure and function of the peritoneum, as well as its close connection with the omentum. An important point in resolving peritonitis is to maintain the balance of cytokines, the activity of immunocytes and complement functioning in the immune lymphoid clusters of the peritoneum and omentum, and their collaborative action during inflammation. The review presents data on the structure and function of the peritoneum and omentum, the role of neutrophil, macrophage, lymphocytic links of the immune system, as well as those of pro- and anti-inflammatory cytokines and complement in the development and cessation of acute inflammation in the abdominal cavity.
Wind Speed Regression Model in Forecasting Wave Height in the Shipping Channel Zone
Authors: Asmaul Husnah  , Abdillah Abdillah , Vera Mandailina  , Syaharudin Syaharudin , Mehmood Saba
Published: March 2023

Nowadays, there are often accidents such as the sinking of ships in water areas that are caused by weather factors, one of which is the extreme wind speed. Wind speed and strong waves in the sea are interrelated because the factor that affects the strength of the wave blow is wind speed. This study aims to provide information about the angina speed regression model to find out the wave height at the sea crossing port. This research is a quantitative research. The data used is in the form of wind speed data taken at the coordinates of Lembar Port and Labuan Bajo Port from the NASA sub-agroclimatology website from January 1, 2012, to December 31, 2021 (for 10 years). This case study uses linear regression analysis and is operated using SPSS software. The data shows that in Lembar Port has the most extreme wind speed fluctuations in the 6th and 7th years. While the wind speed fluctuations in Labuan Bajo are consistent, but slightly extreme in the 7th year surpassing the 1st year. The results showed that the R-Square of Lembar port was 15.4% while the R-Square of Labuan Bajo port was 16.2%. The results of this study.
Effect of Biopotting Quality on Growth and Morphological Quality of Jackfruit Artocarpus heterophyllus Lamk. Seedlings
Authors: Santosa Slamet , Munif Said Hassan  , Abdul Hayat Kasim  , Rizki A.P. Santosa
Published: March 2023

Biopotting was a pot of growing medium for plant seedlings that was environmentally friendly. This study analyzed the effect of biopotting quality  made from clay, fruit waste compost of rambutan, jackfruit, durian,  market compost and tapioca flour on the growth and morphological quality of jackfruit seedlings. The results of the chemical analysis of biopotting samples containing organic C ranged from 42- 44%, total N ranged from 0.21-0.35%, total P ranged from 28.14-38.25 mgkg-1, potassium (K) ranged from 0.90-1.13me/100g and pH ranged from 4.08-6.68. Physical analysis of biopotting obtained water content ranged from 2.04-3.09%, density ranged from 0.42-0.50gcm-3, water absorption ranged from 200-242% and the level of damage to all biopotting was ≤ 2% so it was included in the undamaged category. Measurement of growth and morphological quality of jackfruit seedlings aged 60 days obtained an average height ranged from 17.85-27.6cm,  an average of stem diameter ranged from 0.43-0.47cm, number of leaves ranged from 3-4 strands, root length ranged from 12.5-16.8cm and morphological quality index ranged from 0.092- 0.099. This study concluded that the best quality on M4 biopotting had a significant effect on the growth and morphological quality of the jackfruit Artocarpus heterophyllus Lamk. seedlings
Potential of Chlorella sp Microalgae to Remove Nutrients from Gray Water in the Sequencing Batch Biofilm Reactor (SBBR) System
Authors: Anggraini Melina Dwi , Elystia Shinta , Andrio David
Published: March 2023

In general, domestic wastewater is divided into two, namely black water and gray water. Gray water waste is usually disposed of directly into drainage and water bodies without prior treatment before being discharged into water bodies, so that it can potentially cause water pollution. Grey water waste that is discharged directly into drainage or water bodies has the potential to cause pollution in water bodies. The high content of organic matter in grey water causes grey water waste to be treated first. One of the grey water treatment that can be done is by utilizing microorganisms. The microalgae Chlorella sp. can utilize organic matter as a source of nutrients for growth. This study aims to remove COD and ammonia parameters contained in grey water. SBBR processing is carried out with variations in the comparison of filling and reaction time, namely 30% : 70%, 40% : 60%, 50% : 50% and 60% : 40% and variation in the number of cycles of 4 cycles and 6 cycles. The best results for COD removal was 85% and ammonia removal was 77% in a reactor with comparison of filling and reaction time of 30% : 70% and the number of cycles is 4 cycles.
Implementation of Complex Life Support System for Reef Fish Communities in Cylindrical Oceanariums
Authors: Prasetiawan Nanda Radhitia , Ma'muri Ma'muri , Setiawan Agus , Kurniasih Ratna Amalia , Bramawanto Rikha , Mulyadi Usep
Published: March 2023

The schooling aquarium is cylindrical public oceanarium facilities with 137,000 l volume at PIAMARI Aquarium, Pangandaran. There are not many discussions related to oceanariums in Indonesia and this paper describes the live support system design, biota communities, and management of fish keeping in a oceanarium. Inventarisation of fish species composition, plankton, ectoparasites, and diseases was conducted in this oceanarium, The Oceanarium uses artificial lighting and a recirculation system with a sump equipped with physical, biological, protein skimmers, and ozone generators. Partial water change is applied to maintain the water quality. This oceanarium is a place for 16 fish species types of omnivores, planktivores, and herbivorous originate from Pangandaran waters and belong to IUCN LC conservation status. The fish is well adapted to the oceanarium environment, and each species has different behaviors.. Ten genus of plankton were identified in the oceanarium with diversity belonging to the medium category and become the highest compared to other oceanariums in the PIAMARI environment. Trichodesmium sp. was the highest abundance of plankton genus in the oceanarium. There is a low parasite infestation of Neobenedia sp. in 3 fish species from 2 families (Chaetodontidae and Siganidae). The introduction of coral in the schooling aquarium can be considered by increasing the biological filtration of the sump.
Design of Mercury Interim Storage for Medical Devices Containing Mercury
Authors: Putri Natari Ratna  , Sri Lusiani
Published: March 2023

The Indonesian government is committed to protecting the public from the dangers of mercury. One of the attempts planned is to withdraw mercury medical devices from all health facilities. Storage and monitoring of these medical devices must also be carried out properly and follow mercury handling procedures through mercury interim storage facilities. In building Mercury Interim Storage (MIS), several things need to be designed, including storage areas, ventilation systems, office areas, leak containers, and storage shelves. All of these designs must meet the guidelines and criteria to store mercury safely before being stored in a final storage. In this study, Mercury Interim Storage is designed to keep thermometers and sphygmomanometers, which is estimated to accommodate 10,000 and 1,900 units, respectively.
Pyrolysis of Saw Waste Biomass Mahogany Wood and Polypropylene Plastic
Authors: Safitri Diya Zalfa Aisyah , Wijayanto Danar Susilo , Saputra Taufik Wisnu
Published: March 2023

Fuel requirement increased along with the increased of population also industrial progress, meanwhile the alternative fuel always decreasing. People also faced by the problem of increasing amount of waste, either its organic or anorganic. In this case mahogany waste and polypropylene plastic waste which still rarely used by people can be a solution to make an alternative fuel processed by pyrolysis process. This study is using experiment method with analysis descriptive quantitative technique. This study conducted with pyrolysis process to mixed biomass sawdust mahogany and polypropylene plastic waste with the 100%-0%,75%:25%, 50%:50%, 25%:25%, and 0%:100% ratio, next are do pyrolysis oil test which was quantity test. there is an influence of variety mixed biomass sawdust mahogany and polypropylene plastic waste ratio to quantity of  pyrolysis oil. The most quantity is produced by mixed variety 100% of polypropylene plastic as much as 1026,67 ml with 391°C temperature on T1, 345°C on T2, 367,75°C on T3.
The Effect of Chi Square Feature Selection on the Naïve Bayes Algorithm on the Analysis of Indonesian Society's Sentiment About Face-to-Face Learning During the Covid-19 Pandemic
Authors: Habiba A. , Isnanto R. Rizal , Suseno J.Endro
Published: March 2023

Criticisms and comments submitted to the Indonesian people regarding government policies regarding face-to-face learning during the Covid-19 pandemic have pros and cons. Not a few parents are worried about this policy because parents are still afraid of the spread of the new cluster of Covid-19 in Indonesia which is growing while on the other hand many people who think this is good to apply considering that online learning is considered less effective because many students are difficult to receive material delivered by teachers online and many students who do not have adequate tools. The number of opinions written on Twitter requires classifying according to the sentiments they must get the tendency of these opinions whether they tend to have neutral opinions, positive or negative. Sentiment analysis in this study was conducted using the Naïve Bayes method and chi square's characteristic selection in conducting classification. The results of the analysis of the Naïve Bayes method with chi square characteristic selection have an accuracy of 93% and without chi square characteristic selection has an accuracy of 92%, so it can be concluded the Naïve Bayes Method with chi square characteristic selection has a better accuracy compared without using chi square characteristic selection.
Biodiesel Washing Machine From Esterification Process Equipped With A Cooling System
Authors: Hendriko Hendriko
Published: March 2023

Biodiesel is a fuel that can be recycle, is easily obtained, and friendly to the environment. The production process of biodisesl is divided into four stages, they are the esterification process, cooling, washing and filtration. In this study, a biodiesel purifying machine was developed which is equipped with a cooling system. The cooling system uses a thermoelectric module attached to the delivery pipe from the esterification tank to the purifyer tank. The washing process begins with a pre-cooled hot oil deposition process for 20 minutes to obtain two phases of glycerol and crude biodiesel. The glycerol phase is removed by opening the valve at the bottom of the tank. After that the washing process takes place by mixing water and biodiesel. The mixture of water and distilled water was precipitated for 20 minutes and after that the dirty water was discharged through a valve driven by a servo motor. The purifying machine has been successfully developed and has been tested to perform the expected task. The test results show that the temperature sensor work well. Other tests were carried out on the accuracy of valves and flowmeters. The test results show that the test at low volume is relatively less accurate. Accurate results are obtained on testing volumes above 1500 ml. The purifying machine has been tested to perform the function of purifying crude biodiesel. The test results show that the washing process can take place well.
Optimization of CIDR1α-PfEMP1 Gene Transformation in Eschericia coli BL21(DE3) by Heat-shock Method: Stages of Malaria Vaccine Development
Authors: Dewantoro Dicky , Sulistyaningsih Erma , Dewi Rosita
Published: March 2023

Malaria is still a world health problem, especially in developing countries. Data from the World Malaria Report 2020, malaria cases in the world in 2019 reached 229 million cases with a total death of 409,000 people. The highest mortality occurred in patients under five, which reached 272,000 people. The high mortality rate of severe malaria worldwide needs multiple approaches including the malaria vaccine. Cysteine-rich Interdomain Regions 1α-Plasmodium falciparum Erythrocyte Membrane Protein 1 (CIDR1α-PfEMP1) is a candidate for malaria vaccine due to its important role in malaria pathogenesis. The development of CIDR1α-PfEMP1-based malaria vaccine is conducted by DNA recombinant technology where transformation is a pivotal step. The study aimed to optimize the transformation of CIDR1α-PfEMP1 into Escherichia coli BL21(DE3) using heat shock method to find out the highest transformation efficiency. The variables were duration of heat shock in 30, 50, and 70 secs and plating volume of 100 µL and 200 µL. The results showed that the highest transformation efficiency was 1.9 x 102 CFU/µg, it was achieved by 50 secs heat shock and 200 µL plating volume. This was an optimum transformation condition that can be used further for cloning of CIDR1α-PfEMP1 gene to develop a malaria vaccine.
Analysis of Magnetic Material Abundance in Black Sand
Authors: Rachmawati Dewi Oktofa , Nurfa Risha  , Iwan Suswandi
Published: March 2023

The analysis of the magnetic material abundance on the black sand of Nyanyi beach revealed magnetic material content, grain size, density, magnetic mineral content, and magnetic susceptibility value.The results of this study can be used for black sand development inTabanan district. The black sand magnetic material was determined by the extraction method. Mineral content was tested by using XRF equipment, and the magnetic properties of black sand were determined by using a Bartingtons MS2 Magnetic Susceptibility Meter and a Vibrating Sample Magnetometer. The data were analyzed descriptively quantitatively. The results show thatNyanyi beach sand physically has a characteristic dark gray color, tends to be black, and shiny with a weight fraction of magnetic material reaching 95.52%.The density of the magnetic material is 2072.6 with varying grain sizes of 53 600 .The average value of magnetic susceptibility is 27.212x 10-with Fe2O3magnetic mineral content of 86.68% and the element of Fe is 89.41%.The values of saturation magnetization, remanance magnetization, and coervicity reach37.74; 4.64; 103.93 Oe.
Comparing Surgical Interventions for Recurrent Lumbar Disc Herniation: A Literature Review
Authors: ALSHARAF Yusuf , ALBAQALI MOHAMED ABDULLA , Saloom Fareed , Alqallaf Abdulla hasan , Sayyad Dr. Yakub
Published: March 2023

The recurrence of lumbar disc herniation (LDH) is a common complication that can occur after primary discectomy. Various factors contribute to the recurrence of LDH, including patient-related, surgical, and biomechanical factors. Despite attempts to determine the best surgical techniques and patient selection criteria, there is inconsistent evidence that some factors increase the likelihood of recurrence. Repeat discectomy has been shown to be a safe and effective surgical option for recurrent LDH cases that do not respond to non-operative management. However, selecting the most suitable surgical intervention, such as endoscopic or conventional discectomy with or without instrumented fusion, can be difficult. Factors such as presenting symptoms, previous surgeries or re-herniations, radiographic instability, sagittal or coronal deformity, and surgeon experience should all be considered when making this decision. Further comparative clinical investigations are needed to establish the best surgical method.
PENGARUH SUPLEMENTASI TEPUNG MAGGOT (BLACK SOLDIER FLY) TERHADAP PERFORMA AYAM JOPER FASE STARTER
Authors: Julian Hendrik , Sutrisna Rudy , Riyanti Riyanti , Nova Khaira
Published: March 2023

Penelitian ini bertujuan untuk mengetahui pengaruh suplementasi tepung Maggot (Black Soldier Fly) dan level pemberian terbaik terhadap performa ayam joper fase starter.  Penelitian ini dilaksanakan pada Januari--Maret 2022 dan berlokasi di Jl. Padat Karya No.6, Labuhan Dalam, Kec. Tj. Senang, Kota Bandar Lampung.  Rancangan percobaan menggunakanancangan Acak Lengkap (RAL) dengan 4 perlakuan dan 5 ulangan, sehingga berjumlah 20 unit percobaan. Perlakuan yang diberikan yaitu ransum BR-1 (P0), ransum BR-1 dengan suplementasi 5% tepung Maggot (P1), ransum BR-1 dengan suplementasi 10% tepung Maggot (P2), dan ransum BR-1 dengan suplementasi 15% tepung Maggot (P3).  Peubah yang diukur adalah konsumsi ransum, pertambahan bobot tubuh, konversi ransum dan income over feed cost.  Data yang diperoleh dianalisis menggunakan Analisis of Varians (ANOVA) dengan taraf nyata 5% dan atau 1% kemudian dilanjutkan dengan uji lanjut Duncan.  Hasil penelitian menunjukan bahwa suplementasi tepung Maggot pada BR-1 tidak berpengaruh nyata (P>0,05) terhadap konsumsi ransum dan pertambahan bobot tubuh, tetapi berpengaruh nyata (P<0,05) terhadap konversi ransum dan berpengaruh sangat nyata (P<0,01) terhadap income over feed cost.  Konsumsi ransum, pertambahan bobot tubuh, konversi ransum dan income over feed cost terbaik terdapat pada perlakuan kontrol (P0).
GAMBARAN DARAH (Eritrosit, Hemoglobin, dan Hematokrit) AYAM KAMPUNG JANTAN (Gallus gallus domesticus) SETELAH PEMBERIAN IMUNOMODULATOR EKSTRAK SAMBILOTO (Andrographis paniculata)
Authors: Rahmawati Reni , Siswanto Siswanto , Nova Khaira , Santosa Purnama Edy
Published: March 2023

Penelitian ini bertujuan untuk mengetahui gambaran darah (eritrosit, hemoglobin, dan hematokrit) pada ayam kampung jantan yang diberi ekstrak Sambiloto (Andrographis paniculata).  Penelitian dilaksanakan pada Januari--Maret 2022 di unit kandang Laboratorium Lapang Terpadu, Fakultas Pertanian, Universitas Lampung.  Pemeriksaan sampel darah dilakukan di Laboratorium Patologi Klinik, Fakultas Kedokteran Hewan, Universitas Gadjah Mada.  Penelitian menggunakan 4 perlakuan dan 3 ulangan. Perlakuan yang diberikan melalui air minum dengan P0: (kontrol), P1: 3 mg/kg BB/hari ekstrak Sambiloto (Andrographis paniculata), P2: 6 mg/kg BB/hari ekstrak Sambiloto (Andrographis paniculata), P3: 12 mg/kg BB/hari ekstrak Sambiloto (Andrographis paniculata).  Data yang diperoleh dianalisis secara deskriptif.  Hasil penelitian menunjukkan bahwa ayam kampung jantan yang diberikan ekstrak Sambiloto dapat mempertahankan jumlah eritrosit, hemoglobin, dan hematokrit pada kisaran normal.
PENGARUH PENGOLAHAN KIMIA DAN BIOLOGIS PADA KELOBOT JAGUNG TERHADAP KANDUNGAN ADF DAN NDF
Authors: Rahman First Riyatna , Sutrisna Rudy , Fathul Farida , Liman Liman
Published: March 2023

Penelitian ini bertujuan untuk mengetahui pengaruh pengolahan kimia dan biologis serta pengolahan terbaik pada kelobot jagung terhadap kandungan ADF dan NDF.  Penelitian ini dilaksanakan pada Januari sampai Maret 2022 bertempat di lahan perkebunan milik petani, kecamatan Tanjung Bintang, Lampung Selatan, dan Laboratorium nutrisi dan teknologi pakan, Jurusan peternakan, Universtas Lampung, serta Laboratorium nutrisi perah, fakultas peternakan, Institut Pertanian Bogor.  Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan dan 4 ulangan sehingga terdapat 16 satuan percobaan.  Perlakuan yang digunakan yaitu P1 (Kontrol), P2 (amoniasi), P3 (fermentasi), dan P4 (amofer). Data yang diperloleh analisis ragam pada taraf nyata 5% dan 1% yang selanjutnya dianalisis menggunakan uji lanjut Berganda Duncan.  Hasil analisis ragam menunjukkan bahwa perlakuan amoniasi, fermentasi, dan amofer berpengaruh nyata (P<0,05) terhadap kadar ADF dan NDF. Disimpulkan bahwa perlakuan terbaik untuk menurunkan kadar ADF dan NDF pada kelobot jagung yaitu menggunakan pengolahan amofer dengan hasil kadar ADF 41,36% dan NDF 82,55%.
TINGKAT INFESTASI DAN JENIS PARASIT SALURAN PENCERNAAN PADA SAPI PERANAKAN SIMENTAL DI KECAMATAN TULANG BAWANG UDIK KABUPATEN TULANG BAWANG BARAT
Authors: Khair Ajmal Kurniawan , Hartono Madi , Wanniatie Veronica , Dakhlan Akhmad
Published: March 2023

Penelitian yang dilaksanakan pada Oktober 2022 yang bertujuan untuk mengetahui tingkat infestasi dan jenis parasit saluran pencernaan pada Sapi Peranakan Simental di Kecamatan Tulang Bawang Udik, Kabupaten Tulang Bawang Barat. Metode penelitian yang digunakan adalah metode survei. Jumlah sampel yang diperoleh yaitu 113 sampel yang berasal dari 71 peternak. Pemeriksaan sampel feses sapi Peranakan Simental dilakukan di Balai Veteriner, Kota Bandar Lampung menggunakan metode Mc. Master dan uji Sedimentasi. Data disajikan dalam bentuk tabel dan histogram,        kemudian dianalisis secara deskriptif. Hasil menunjukkan bahwa jenis parasit saluran pencernaan yang menginfestasi sapi Peranakan Simental di Kecamatan Tulang Bawang Udik Kabupaten Tulang Bawang Barat yaitu Paramphistomum sp., Eimeria, Haemoncus sp., Oesophagustomum sp., Fasciola sp., Toxocara sp., dan Tricuris sp. Tingkat infestasi parasit saluran pencernaan pada Sapi Peranakan Simental di Kecamatan Tulang Bawang Udik  sebesar 73,45% dengan prevalensi cacing sebesar 61,06% dan prevalensi Eimeria sebesar 49,56%. Infestasi tunggal parasit saluran pencernaan pada sapi Peranakan Simental sebesar 38,55% (Paramphistomum sp., Eimeria, Haemoncus sp., Oesophagustomum sp., Fasciola sp., Toxocara sp., dan Tricuris sp.), infestasi campuran 2  jenis parasit saluran pencernaan (Paramphistomum sp. dan Eimeria, Haemoncus sp. dan Paramphistomum sp., Oesophagustomum sp dan Eimeria) sebesar 45,78%, infestasi 3 jenis parasit saluran pencernaan  (Haemoncus sp., Paramphistomum sp., dan Eimeria, Oesophagustomum sp Paramphistomum sp, dan Eimeria, Haemoncus sp., Fasciola sp, dan Eimeria) sebesar 14.46%, dan infestasi campuran lebih dari 3 jenis parasit saluran pencernaan (Haemonchus sp., Trichuris sp., Paramphistomum sp., dan Eimeria) sebesar 1,20%.
İşe alım süreçlerinde aşamalı olarak TOPSIS ve VIKOR yöntemleri uygulanarak iş gören seçimi yapılması
Authors: ASLAN Abdulbari , HÜSEYİNOĞLU Mesut , BUDAK Cafer
Published: March 2023

Değişen ve gelişen dünyada kurumların daha rekabetçi ve sürdürülebilir yönetim süreçlerinde karar verme oldukça önemli bir yer edinmiştir. Son 80 yılda tamamen sistemli bir disiplin ve model halini alan karar verme bilimi tüm organizasyon ve yaşam alanlarına yön vermeye devam etmektedir. Tüm şirketler için hayati bir öneme sahip olan ve gittikçe daha da önem kazanan çalışan etmeni ve çalışan seçimi de karar verme modelleri ile yönetilmeye başlanmıştır. Bu çalışmada öncelikle karar verme modelleri hakkında bilgiler sunulmuştur. Daha sonra Çok Kriterli Karar Verme (ÇKKV) modellerinden TOPSIS yöntemi kullanılarak iş başvurusu yapan 8 adaydan 4 kişilik mülakat listesi oluşturulmuştur. Son olarak seçilen adaylar içinden en uygun adayı tercih etmek için VIKOR yöntemi uygulanmış ve başarılı sonuçlar elde edilmiştir.
Use of Photomath Applications in Helping Improving Students’ Mathematical (Algebra) Achievement
Authors: Zain Iffah N. M. , Setambah Mohd A. B. , Othman Mohd S. , Hanapi Mazarul H. M.
Published: March 2023

This action research was conducted to help five Form Two Students improve their math achievement especially in Factoring and Algebraic Development. The study sample consisted of five students who got low results in the pre-test. The selection of research respondents was carried out by purposive sampling involving five students in a secondary school. This action research also gives researchers the opportunity to improve teaching and learning practices using the Photomath application. Data for this study was collected through observation, pre-test, post-test and questionnaire. The collected data was then analyzed in terms of frequency and percentage. The results of the Post Test for the five respondents, show an increase in math achievement and more interest in math subjects when they can refer to this Photomath application based on the calculations they have done. The use of this application can be widely used as a tool to help students when they are at home and do not have a reference to refer to. The implications of this study show an increase in the respondents’ achievement and interest in algebra.
Investigation of the Relationship Between Anger Control and Self-Disclosure
Authors: Arslan Nihan , Öztürk Fatma Nur
Published: March 2023

The aim of the study was to examine the relationship between anger control and self-disclosure. In addition, within the scope of the research, the demographic variables of the sample of adolescents' anger control, and self-disclosure variable; gender;class level. Anger Control Scale for Adolescents is a 26-item measurement tool that includes a four-point Likert response format (almost never, sometimes, often, and almost always). The sample of the study consists of 653 adolescents. 370 students are female and 253 students are male. Within the scope of the scale adaptation study, reliability was examined with item analysis corrected item-total score correlation and confirmatory factor analysis. In the confirmatory factor analysis for the scale, it was observed that the uni-dimensional model fitted well. The reliability coefficient of the scale was found to be .86. As a result of the research; the anger control level of adolescents did not differ according to gender. There was no significant difference between the digital commitment levels of female and male students. Also, the anger control level of adolescents did not differ according to the class variable. There is no significant difference between the anger control level of female and male students. In addition, the level of self-disclosure of adolescents did not differ according to the gender variable. There was no significant difference between the self-disclosure levels of female and male students. Also, the level of self-disclosure of adolescents did not differ according to the class variable. There was no significant difference between the self-disclosure levels of female and male students. Finally; there was a significant relationship between the levels of self-disclosure and anger control levels of adolescents.
Short report on the fauna of ant-lion and owl-fly (Neuroptera) from Socotra Archipelago
Authors: Ábrahám Levente
Published: March 2023

In 2009, seven ant-lion and one owl-fly species and subspecies were collected in Socotra Islands (Yemen). Half of the collected species are endemic. Myrmeleon saldaitisi sp. n. is described and compared to Myrmeleon fasciatus (Navás, 1912) and Myrmeleon sanaanus (Navás, 1929). Description of Myrmeleon hyalinus isolatus ssp. n. is given and its local population is separated from the other subspecies. Differential diagnosis is given for Centroclisis lineata (Kirby 1903) and Centroclisis speciosa Hölzel, 1983. Endemic ant-lions Echthromyrmex insularis Kimmins, 1961, Centroclisis lineata (Kirby, 1903) and Neuroleon socotranus (Taschenberg, 1883) are illustrated by figures and photos.
Provisional atlas and checklist of the Alucitidae fauna of Hungary (Lepidoptera)
Authors: Fazekas Imre
Published: March 2023

Hungarian Alucitidae are revised and a list of localities is provided. Biology, habitats and comments on the limits of the distribution are given. 8 species and 2 genera are known from Hungary. Provisional grid map of the distribution area of the all species in Hungary. This list is used as a guide for the provisional distribution maps of the species. In the material available now, Alucita cancellata (Meyrick, 1908) and A. palodactyla Zeller, 1847 are mentioned new for Hungary.
További adatok a Mecsek-hegység puhatestű (Mollusca) fajainak elterjedéséhez
Authors: Uherkovich Ákos
Published: March 2023

Author presents all of his malacological distribution data concerning to Mecsek Mountains and its environs. 101 species (belonging to 36 families) are enumerated from 284 localities. Number of full data surpass 4000. Nine species – Pomatias rivularis (Eichwald, 1829), Pomatias elegans (O. F. Müller, 1774), Platyla polita (W. Hartmann, 1840), Unio pictorum (Linnaeus, 1758), Anodonta cygnea (Linnaeus, 1758), Sinanodonta woodiana (Lea, 1834), Pisidium amnicum (O. F. Müller, 1774), Pisidium nitidum Jenyns, 1832 and Pisidium milium Held, 1836 – were not published from here earlier.
Oclacitinib 10 years later: lessons learned and directions for the future
Authors: Marsella Rosanna , Doerr Katherine , Gonzales Andrea , Rosenkrantz Wayne , Schissler Jennifer , White Amelia
Published: March 2023

Oclacitinib was approved in the United States 10 years ago for the management of atopic dermatitis (AD) and allergic skin disease in dogs. Many studies and case reports have been published in the past 10 years on the efficacy and safety of this medication, both at labeled doses to treat allergic dogs and off label to treat other diseases and given to other species. Concerns and confusion have occurred for both clinicians and owners regarding the long-term safety of this drug. The purpose of this review is to present the current knowledge on the efficacy, speed of action, effects on the immune system, and clinical safety of oclacitinib, based on evidence and published literature. We also aim to summarize the lessons learned in the past 10 years and to propose directions for the future.
A Platform for Collaboration: The Views of Civil Society Organisations on a Local Compact
Authors: Kolmodin Sophie
Published: March 2023

A considerable degree of collaboration between civil society organisations (CSOs) and governmental organisations (GOs) occurs in various collaborative areas, such as collaborative platforms, that aim to increase mutual understanding and reach shared solutions to complex social challenges. However, little is known regarding how CSOs relate to and discuss the starting conditions for participating in collaborative platforms. By highlighting the perspectives of CSOs supporting refugees, this article shows that the starting conditions affect whether CSOs decide to participate. Nevertheless, the starting conditions are also essential for their general understanding of the platform’s aim and purpose, thus affecting more than the initial decision to participate or not. A primary barrier to their participation is the political agenda behind the platform and what role CSOs think they should have in society. Consequently, the inclusive ‘whole society approach’ that collaborative platforms intend to create might be out of reach before starting the collaboration.
Current-zero-crossing Shift for Compensation of Dead-time Distortion in Pulse-width-modulated Voltage Source Inverter
Authors: Chatterjee Dipankar , Chakraborty Chandan , Mukherjee Kaushik , Dalapati Suvarun
Published: March 2023

Accurate current polarity detection is a major issue for successful compensation of dead-time distortion in pulse-width-modulated (PWM) voltage source inverter. The present study is concerned with the concept of shift in current-zero-crossing due to dead-time distortion compensation that results in error in current polarity detection and thus causes a problem with regard to the successful continuation of compensation. The phenomenon is analysed in detail, along with its dependence on different factors. The proposed concept is validated in digital simulation and also through experimental verification. The study also recommends the possible correction to be incorporated in view of such zero-crossing shift for achieving proper compensation, especially in case of current-sensor-less compensation techniques.
Kwartety smyczkowe Hanny Kulenty. Pamięć gatunku a współczesne środki ekspresji
Authors: Nowak Anna
Published: March 2023

In the work of Hanna Kulenty, a string quartet appears as a significant form of artistic expression. Its successive incarnations (6 quartets created in 1983-2014) illustrate the evolution of the musical language of composers, her approach to the problem of form, time, space, and sound. The article is an attempt to capture the idiomatic features of this music, presented in the context of Bakhtin’s theory of genre as a representative of creative memory, and to indicate the place of quartets in contemporary chamber music by Polish composers.
Association of OPRM1, MIR23B, and MIR107 genetic variability with acute pain, chronic pain and adverse effects after postoperative tramadol and paracetamol treatment in breast cancer
Authors: Vidic Zala , Goricar Katja , Strazisar Branka , Besic Nikola , Dolzan Vita
Published: March 2023

Background

Tramadol is an opioid analgesic often used for pain management after breast cancer surgery. Its analgesic activity is due to the activation of the μ-opioid receptor, encoded by the OPRM1 gene. This study investigated the association of genetic variability in OPRM1 and its regulatory miRNA genes with outcomes of tramadol/paracetamol treatment after breast cancer surgery with axillary lymphadenectomy.

Patients and methods

The study included 113 breast cancer patients after breast cancer surgery with axillary lymphadenectomy treated with either 75/650 mg or 37.5/325 mg of tramadol with paracetamol for pain relief within the randomized clinical trial KCT 04/2015-DORETAonko/si at the Institute of Oncology Ljubljana. All patients were genotyped for OPRM1 rs1799971 and rs677830, MIR23B rs1011784, and MIR107 rs2296616 using competitive allele-specific PCR. The association of genetic factors with acute and chronic pain as well as adverse effects of tramadol treatment was evaluated using logistic regression, Fisher’s exact test, and Mann-Whitney test.

Results

The investigated OPRM1 related polymorphisms were not associated with acute pain assessed with the VAS scale within four weeks after surgery (all P > 0.05). Carriers of at least one polymorphic OPRM1 rs1799971 allele had a higher risk of constipation in the first four weeks after surgery compared to non-carriers (OR = 4.5, 95% CI = 1.6–12.64, P = 0.004). Carriers of at least one polymorphic OPRM1 rs677830 allele had a higher risk of constipation after third week of tramadol treatment (OR = 3.11, 95% CI = 1.08–8.89, P = 0.035). Furthermore, carriers of two polymorphic MIR23B rs1011784 alleles had a higher risk of nausea after 28 days of tramadol treatment (OR = 7.35, 95% CI = 1.27–42.6, P = 0.026), while heterozygotes for MIR107 rs2296616 allele had a lower risk of nausea after 21 days of tramadol treatment (OR = 0.21, 95% CI = 0.05–0.87, P = 0.031). In carriers of two polymorphic MIR107 rs2296616 alleles, chronic pain was significantly more common than in carriers of two wild-type alleles (P = 0.004). Carriers of at least one polymorphic MIR23B rs1011784 allele experienced more neuropathic pain after adjustment for tramadol dose (OR = 2.85, 95% CI = 1.07–7.59, P = 0.036), while carriers of at least one polymorphic OPRM1 rs677830 allele experienced less neuropathic pain compared to carriers of two wild-type alleles (OR = 0.38, 95% CI = 0.15–0.99, P = 0.047).

Conclusions

Genetic variability of OPRM1 and genes coding for miRNAs that could affect OPRM1 expression may be associated with adverse effects of tramadol/paracetamol treatment as well as with chronic and neuropathic pain after breast cancer surgery with axillary lymphadenectomy.
CT-guided 125I brachytherapy for hepatocellular carcinoma in high-risk locations after transarterial chemoembolization combined with microwave ablation: a propensity score-matched study
Authors: Chen Zixiong , Fu Xiaobo , Qiu Zhenkang , Mu Maoyuan , Jiang Weiwei , Wang Guisong , Zhong Zhihui , Qi Han , Gao Fei
Published: March 2023

Background

This study aimed to evaluate the safety and efficacy of 125I brachytherapy combined with transarterial chemoembolization (TACE) and microwave ablation (MWA) for unresectable hepatocellular carcinoma (HCC) in high-risk locations.

Patients and methods

After 1:2 propensity score matching (PSM), this retrospectively study analyzed 49 patients who underwent TACE +MWA+125I brachytherapy (group A) and 98 patients who only received TACE +MWA (group B). The evaluated outcomes were progression-free survival (PFS), overall survival (OS), and treatment complications. Cox proportional hazards regression analysis survival was used to compare the two groups.

Results

The patients in group A showed a longer PFS than group B (7.9 vs. 3.3 months, P = 0.007). No significant differences were observed in median OS between the two groups (P = 0.928). The objective response rate (ORR), disease control rate of tumors in high-risk locations, and the ORR of intrahepatic tumors were 67.3%, 93.9%, and 51.0%, respectively, in group A, and 38.8%, 79.6% and 29.6%, respectively, in group B (P < 0.001, P = 0.025 and P = 0.011, respectively). TACE-MWA-125I (HR = 0.479, P < 0.001) was a significant favorable prognostic factor that affected PFS. The present of portal vein tumor thrombosis was an independent prognostic factor for PFS (HR = 1.625, P = 0.040). The Barcelona clinic liver cancer (BCLC) stage (BCLC C vs. B) was an independent factor affecting OS (HR = 1.941, P = 0.038). The incidence of complications was similar between the two groups, except that the incidence of abdominal pain was reduced in the group A (P = 0.007).

Conclusions

TACE-MWA-125I resulted in longer PFS and better tumor control than did TACE-MWA in patients with unresectable hepatocellular carcinoma in high-risk locations.
Iatrogenic Acute Aortic Dissection Complicating Coronary Catheterization
Authors: Macovei Liviu , Adoamnei Marius , Dumitrescu Irina , Panţiru Raluca-Mihaela , Năstasă Dan , Sascău Radu Andy , Stătescu Cristian
Published: March 2023

Coronary dissection extending to the ascending aorta is an uncommon complication of invasive coronary procedures which carries a life-threatening risk. The performance of percutaneous coronary intervention (PCI) at centers without emergency surgical instruments has increased awareness of potential complications. We report a case of iatrogenic aortocoronary dissection in a patient admitted with acute myocardial infarction (AMI) who was treated during angioplasty.

The responsible mechanism for the occurrence of aortic dissection during PCI remains to be discovered. In this case, brisk sealing of the entry site of the dissection with a stent to prevent extension of the aortic dissection appears to be safe and feasible, with good short- and long-term outcomes.
Diet composition of the long-legged buzzard (Buteo rufinus) in southeastern Bulgaria
Authors: Dravecký Miroslav , Shurulinkov Petar , Dilovski Georgi , Revický Michal , Daskalova Girgina , Obuch Ján
Published: March 2023

During 2018–2022, the local breeding population of the long-legged buzzard (Buteo rufinus) in southeastern Bulgaria was monitored in the territory of three districts of Sliven, Yambol and Burgas. Diet data were collected in 15 breeding pairs. Overall, we identified 290 prey items. We used three methods for diet analysis that produced different results: (1) collecting prey remains (68 individuals, 23.5%), (2) collecting pellets and skeletal materials (42 individuals, 14.5%), and (3) collecting data on a diet using trail cameras (180 individuals, 62.1%). The dominant part of the diet formed mammalian species (69.3%, ten species and some undetermined Rodentia and other Mammalia). Birds were less represented but with similar species richness (21.0%, 11 species and pigeons (Columba sp.), thrushes (Turdus sp.), undetermined Passeriformes and Galliformes). Compared to birds, the proportion of Reptilia was lower (9.3%, two species). Amphibia were represented only with one specimen of the common toad (Bufo bufo). The dominant diet of long-legged buzzards in southeastern Bulgaria was European souslik (Spermophilus citellus, 31.0%), followed by sibling vole (Microtus mystacinus, 25.5%). Less abundant taxa were undetermined Passeriformes (6.9%), lesser mole rat (Nannospalax leucodon, 5.9%), pigeons (4.5 %), blotched snake (Elaphe sauromates, 3.8%), Balkan green lizard (Lacerta trilineata, 3.5%), European hare (Lepus europaeus, 3.1%), common magpie (Pica pica, 2.8%), Colubridae (1.7%), common blackbird (Turdus merula, 1.4%), domestic chicken (Gallus gallus domesticus, 1.0%) and Eurasian skylark (Alauda arvensis, 1.0%). Spermophilus citellus was the most abundant species in the Yambol district samples and the most abundant species in the data obtained from trail cameras. In the Burgas district, the dominant species was Microtus mystacinus. When comparing the diet spectrum of Buteo rufinus from other authors, birds occurred more frequently than reptiles in our material.