bluuebunny/crossref_metadata_2025 huggingface dataset:
The Religious, Scientific, Cultural, and Economic Foundations of America
Authors: Datta Y.
Published: December 2022

Historian Lynn White wanted to understand why the Western civilization had exploited nature so much that its own quality of life--even its survival--was now at stake. White concluded that the answer is: the Judeo-Christian tradition.The environmental movement began in the early 1960s, with far-reaching changes in American values and attitudes, that were powering a growing interest in wilderness and its preservation.By destroying pagan animism, Christianity made it possible to exploit nature in a mood of indifference to the feelings of natural objects. Severed from the human community and its ethical protection, nature was fully exposed to human greed.Aristotle’s scientific philosophy of nature—animate and alive—dominated Western thought for two thousand years after his death. But thanks to the Scientific Revolution of the 16th and 17th centuries, the notion of an organic and spiritual universe was replaced by that of the world as a machine, and the word machine became a dominant metaphor of the modern era. It was around 1850, that Western Europe and North America arranged a marriage between science and technology that signified the Baconian creed of power over nature. Its acceptance as a normal pattern of action may mark the greatest event in human history since the invention of agriculture. Perhaps the most profound legacy of the Scientific Revolution is the principle of reductionism that encourages an atomistic and disintegrated view of nature. As a result, we have the Faustian bargain of Hydrogen bombs that pose an existential threat to the universe. Individualism is first on the list of American cultural heritage. Next is the “Bootstrap philosophy.” This phrase has become part of American mythology, and the nation’s attitude toward helping those in society that have been left behind; and we lecture them to lift themselves up by their bootstraps. Next are the negative attitudes toward government that are unjustified. Then there is the free-market crusade that has led to American economic decline. And next, this is their promised Utopia for what ails America: “Privatization, deregulation, downsizing, shrinking entitlements, and lower taxes.”Smith’s explanation of the paradox of the interplay between supply and demand, is an important scientific contribution to society. But, why then did he cross that line, and enter the domain of metaphysics with his proclamation that “consumption is the sole end and purpose of all production”?Yet, he put no limits on consumption and left the door of overconsumption wide open.Smith says that in an unfettered market--propelled by competition among self-interested sellers and buyers--the invisible hand will then allocate goods efficiently.However, one of the best-kept secrets in economics is that there is no case for the “invisible hand.”Finally, Adam Smith ignored the Industrial Revolution? This is because his static theory could not handle innovation.
ISOLATION, IDENTIFICATION, AND QUANTIFICATION OF MAJOR FLAVONOID IN LEAVES OF PERESKIA BLEO (KUNTH) DC
Authors: SAPTARINI NYI MEKAR , MUSTARICHIE RESMI , HERAWATI IRMA ERIKA , HADISOEBROTO GINAYANTI
Published: December 2022

Objective: This study aimed to isolate, identify, and quantify major flavonoid in P. bleo leaves from West Java Regency, Indonesia.

Methods: Isolation began with maceration, followed by liquid-liquid extraction and various chromatographic separations. Identification of isolates was carried out using 2D TLC and shifting reagents. Quantification was determined with the colorimetric method.

Results: The results showed that extract, ethyl acetate, and distilled water fractions contain flavonoids. The flavonoid screening showed positive results for flavonols. The vacuum liquid chromatography separated 21 sub-fractions; the 12th and 13th sub-fractions were predicted to contain flavonols.

Conclusion: The novelty of this study was the isolation and identification of the major flavonoid of P. bleo leaves originating from West Java Regency, Indonesia, i.e. catechin. The content of the compound was 3.795±0.096 g QE/ml with a purity of 94.89%.
DISCOVERING TYROSINASE INHIBITORS FROM MORUS SP. PLANTS: AN IN SILICO STUDY
Authors: FALYA YUNIARTI , AMELIA RENNY , RIZIKIYAN YAYAN , SULASTRI LELA , HIDAYATI NUR RAHMI
Published: December 2022

Objective: This study aimed to examine Morus sp. compounds bonding mode with critical amino acid residues in the binding pocket of the enzyme TRP1 in In silico so that it can be used as a support in the design of skin-lightening cosmetics based on Morus sp.

Methods: Docking is done using autodock tools software, chem office 2019, ChemDraw professional 12, autodock 4.2, discovery studio 2016.

Results: Isorhamnetin has two hydrogen bonds to amino acids Met215 and Asn205. Other compounds found in Morus sp., which have hydrogen bonds with Asn205, are dihydromorin, kaempferol, quercitrin, rutin, and morusin.

Conclusion: Isorhamnetin has the best potential among other compounds as a tyrosinase inhibitor by hydrogen binding to the amino acid Met215, and Asn205 has a free energy of-6.16 kcal/mol.
PHARMACOGNOSTIC CHARACTERISTIC OF KAEMPFERIA GALANGA RHIZOME DRIED BY OVEN AND COMBINATION METHODS
Authors: INDRADI RADEN BAYU , SUSILAWATI YASMIWAR , RAMADHANIA ZELIKA MEGA , SAVITRI ASRI , SOLEH SOLEH , ZUHROTUN ADE , ISKANDAR YOPPI
Published: December 2022

Objective: The research objective was to determine the effect of the drying process on the pharmacognostic characteristic of dried Kampferia galanga produced in the Post-Harvest Processing Center of Medicinal Plants facility.

Methods: The drying methods were oven-based drying in 80 °C temperature and a combination-based drying process, which included greenhouse drying for 6-8 h and transfered to 80 °C oven. The pharmacognostic characteristic of products were evaluated based on Indonesian Herbal Pharmacopeia standard, which included macroscopic and microscopic evaluation, thin-layer chromatography, water and ethanol soluble content, total ash and acid-insoluble ash content, volatile oil content, ethyl para-methoxycinnamate content, total plate count, and total yeast and mold count.

Results: The result showed dried K. galanga from both drying methods met the quality standard. Interestingly, the combination-based methods possed 6-7 h quicker in drying time compared to oven-based methods despite lower temperatures was used at the greenhouse.

Conclusion: It can be concluded that both methods could retain the quality of K. galanga rhizome.
THE ANTI-INFLAMMATORY TABLET FORMULATION OF COLEUS (PLECTRANTHUS SCUTELLARIODES) LEAVES EXTRACT USING KOLLICOAT®PROTECT COATING
Authors: MUSTARICHIE RESMI , RAMDHANI DANNI , SAPTARINI NYI MEKAR
Published: December 2022

Objective: The purpose of this study was to find the concentration of weight gain on the use of Kollicoat®Protect to produce coleus leaf extract film-coated tablets with good physical properties.

Methods: Coleus extract was obtained by maceration using 70% ethanol. Tablet cores were prepared using the wet granulation method, then evaluated (uniformity of weight, size, hardness, friability, and disintegration time). Coated tablets were made in four variations of polymer weight gain, i.e. 5, 6, 7, and 8%. To determine the effect of the weight gain concentration of Kollicoat®Protect an evaluation of the coated tablets was carried out, i.e. the uniformity of weight, size, hardness, disintegration time, and physical appearance of the film-coated tablets.

Results: The four variations (Film Coated Tablet, FCT 5, 6, 7, and 8%) in weight gain of film-coated tablets showed the physical appearance results per the applicable requirements. However, the physical observation test at room temperature showed the instability of the film-coated tablet. The qualitative analysis of thin-layer chromatography showed that the productive substances in the extracts, tablet cores, and film-coated tablets were still contained even though they had undergone several formulation stages.

Conclusion: Film-coated tablets met the standards of the Indonesian Pharmacopoeia and the United States Pharmacopeia. After two weeks, there was slight instability in film-coated tablets at room temperature storage. The extract, tablet core, and film-coated tablet contain flavonoids.
A Theological Approach to the Simplest Mathematical Explanation of the Dynamics of the Temporal Universe
Authors: Luyaluka Kiatezua Lubanzadio
Published: December 2022

Guided heuristically by the theism of ancient Egypt where religion underpinned cosmology, to explain the dynamics of the temporal universe (gravitation, rotation, and translation), this paper starts from the existence of individualities and the law of causality to build a cosmological argument, into a natural systematic theology (NST). According to this NST, God (the greatest possible being) includes the creator as one of his celestial manifestations. One deduces from the NST that, manifesting an individuality included in the indivisible and immutable God, the creator expresses the fullness of the Most High in an individual manner. This fullness (the Logos) is thus, like God, a constant power working in the creator. The existence of the temporal universe in God requires the existence of a principle of the mutability of God at the occurrence of creation ex nihilo; in accord to the law of causality this principle must greater than God, which is impossible. Moreover, the existence of creation outside of God implies an entity greater than God including him and creation, this is also impossible as God is the greatest possible being. Therefore, the temporal universe exists in the temporal consciousness of the creator as a mere appearance of, or perspective on, the celestial reality. Thus, the NST dictates the existence of an absolute space-time that includes the Euclidean space-time known in Newtonian physics and corresponds to the temporal consciousness of the creator. The NST proves that to create, the creator had first to leave the eternal plane for the temporal one. Then on, as a constant power, the Logos impels the creator to accelerate back toward the celestial-eternal level. This isotropic acceleration of the creator causes the absolute space-time to accelerate towards its nothingness, its non-existence in the celestial realm. Therefore, this background acceleration of the absolute space-time is the simplest, exhaustive, deterministic, and mathematical explanation of the dynamics of the temporal universe (gravitation, rotation, translation). This explanation offers the advantage of using elementary notions of algebra and analysis and the result applies to the astronomical level as well as to the subatomic one.
On recurrent Light like Hypersurfaces of Indefinite Sasakian Manifold
Authors: Shukla Sushil
Published: December 2022

The object of present paper is to study the properties of recurrent lightlike hypersurfaces of indefinite Sasakian manifold with (l, m) –type connection.
Analyzing the relationship between leadership styles and dynamics work environment in Kurdistan
Authors: Jwmaa Swran Jawamir , Younus Saif Qudama , Othman Baban Jabbar , Rashad Muhammed Khazal , Kanabi Idrees Sadeq , Jamil Diyar Abdulmajeed , Mahmood Rozhgar Khorsheed , Ismail Zaid Saad
Published: December 2022

This study's overarching objective is to learn how certain traits of leaders affect the efficiency of building projects. Five separate building companies in the Kurdish capital of Erbil participated in the study. A quantitative method was used to analyze the data in this study. There are a total of seventy one people in this research. Because the highest value for the charismatic leadership characteristic was determined to be.737>.01 and the P-value was.000, we can conclude that there is a significant positive association between charismatic leadership and the efficiency of project development teams.
A Study on the Effectiveness of the Internal Organizational Communication Process of Alano & Sons Credit Corporation: Basis for Continuous development of Company Operations, Dipolog City, Philippines
Authors: Barrera Lydith Marie Benitez , S. Cabalida Edgardo
Published: December 2022

This study aimed to assess the effectiveness of the internal communication process of Alano & Sons Credit Corporation during the calendar year 2019. This study used the descriptive research design with survey as the chosen data-gathering tool. The effectiveness of the communication process was measured using the components of effective communication. The respondents consisted of 171 regular employees of Alano and Sons Credit Corporation. Frequency counting, percentage, weighted mean, and ANOVA were used to answer the research problems and test the null hypothesis. The study found no significant differences on the level of effectiveness of communication process when employees are grouped in terms of sex, age, highest educational attainment, position, length of service, and area/office of assignment. The study also found that the employees see the overall communication process of Alano & Sons Credit Corporation as effective. This is consistent in all components namely, communicator, message, channel, feedback and environment. Furthermore, the evaluation on the effect of the barriers of communication present within the company found that the employees see them as having a significant effect.
Consumer Purchasing decision: Choosing the Marketing Strategy to influence consumer decision making
Authors: Jamil Diyar Abdulmajeed , Mahmood Rozhgar Khorsheed , Ismail Zaid Saad , Jwmaa Swran Jawamir , Younus Saif Qudama , Othman Baban Jabbar , Rashad Muhammed Khazal , Kanabi Idrees Sadeq
Published: December 2022

The purpose of this study was to investigate the role that marketing strategy plays as a determining element in the decision-making process of consumers. The current study made use of the quantitative research approach by customizing a questionnaire based on information gleaned from academic sources. This particular study had a sample size of 162 participants, all of whom were selected at random throughout the selection process. According to the findings, penetration pricing exerts a substantial and beneficial impact on the decision-making process of consumers at the 5% level. According to the findings, price skimming has a substantial and favorable effect on the decision-making process of consumers at the 5% level. According to the findings, marketing sharing websites have a considerable beneficial impact on the decision-making process of consumers at the 5% level. The findings indicate that blogs have a considerable and beneficial effect on the decision-making process of consumers at the 5% level. According to the findings, competitive pricing has a substantial and favorable impact on the choice-making process of consumers at the 5% level. Furthermore, every beta value exceeds the.001 threshold. All of the models have extremely high adjusted R2, which indicates that the models are very capable of explaining the variance in consumer decision-making that is caused by the variation in the independent variables. The F-value demonstrates that the explanatory variables are jointly statistically significant in the model, and the Durbin-Watson (DW) statistics demonstrate that there is autocorrelation in the models. Both of these findings are supported by the model's positive autocorrelation.
Experimental Evaluation of Rutting Resistance of Sugar Cane Bagasse Ash Modified Asphalt Mixture
Authors: Muhammad Haris Hafiz
Published: December 2022

Abstract: Bagasse ash (BA) was used as filler in hot mix asphalt. Mineral fillers in asphalt concrete mixes have a significant influence on asphalt concrete performance. Although mineral filler is just a minor percentage of the total performance of asphalt concrete, it plays a critical function. Bagasse Ash (BA) was utilized as a filler ingredient to test and assess the performance of asphalt concrete. BA was used in variable ratios to replace Stone Dust (SD) in road construction. Filler was used in varying quantities (4%, 5.5%, and 6.5%). Furthermore, BA is used to replace the traditional SD filler in partial replacements of 10%, and 20%, as well as full replacement of SD. The Marshall Mix Design Method was used with three different amounts of bitumen, namely 4%, 4.3%, and 4.6%. By using National Highway Authority’s (NHA) general criteria for Optimum Binder Content, a total of 108 samples were produced. The prepared mixes showed good outcomes, and the majority of them passed the NHA's main requirements. Some of the mixtures do not meet the VMA and VFA requirements given in MS-2 Asphalt Institute 2014. Two forms of performance testing are the Dynamic Modulus Test and the Wheel Tracking. A total of twelve OBC samples are evaluated for wheel tracking and dynamic modulus. Bagasse Ash has been tested in the lab and found to be capable of being used as filler in both partial and full replacement of conventional stone dust filler.
Parametric Investigation of FDM Process Parameter on Impact Strength of 3D-Printed Part
Authors: Magare Nayan , Harne M. S.
Published: December 2022

Abstract: The method of producing three-dimensional solid items from digital data is known as additive manufacturing (AM), sometimes known as 3-D printing. A rapidly expanding additive manufacturing technique with several applications is fused deposition modeling (FDM). In this study, we investigate how the orientation, infill pattern, and density of the infill affect the impact strength of the ASTM D-256 specimens. A 3- printer with Acrylonitrile Butadiene Styrene (ABS) filament material has been used in this study. To evaluate the impact strength of the printed object and represent their quality, an ASTM D256 specimen standard has been used. The various parameters for the experiment were selected using OVAT analysis. With the help of a design of experiments (DOE) using Taguchi's L9 Array along with infill pattern, orientation, and density, the operational dependence is examined. When analysis of variance (ANOVA) is used to identify the relevant 3D printing process parameter it is shows that orientation and infill pattern are most significant parameters for impact strength.
A Review on Analysis and Design of Prestressed Concrete Bridge by CSiBridge Software
Authors: Balawane Ravindra , Satao Sumit , Mirje Sneha , Gharde Shivani , Deosarkar Prof. Manoj U
Published: December 2022

Abstract: The methods for designing, building, and maintaining buildings, especially bridges, have greatly advanced thanks to computer applications and software. It has streamlined the design process for all bridge types and opened up opportunities to test out novel theories and concepts for more ambitious undertakings. The lifecycle of a bridge now includes computer software and applications at every stage, from conception to bridge management. This essay focuses in particular on the investigation and CSiBridge a software created by the American Based Company and Structures Inc. The CSI Bridge software is an advanced version of Staad Pro and SAP, CSiBridge software is multidimensional programming software specifically created for bridges. Bridge users are quite accustomed to CSiBridge software.
La configuración del campo de estudio de los movimientos sociales en España (1980-2020)
Authors: Betancor Nuez Gomer , Santos Felipe G.
Published: December 2022

El objetivo de este artículo es hacer una primera aproximación a la configuración de los movimientos sociales y la acción colectiva como campo de estudios emergente en España, una tarea que estaba pendiente en la academia. Así, este trabajo analiza cómo la recepción original de las principales teorías y metodologías ha influido, a su vez, en las principales líneas de investigación desarrolladas (y omitidas) en España. Y constatamos, como ya han apuntado otros autores, que los estudios sobre movimientos sociales han reforzado su papel y relevancia en España de forma paulatina en la última década, pero con cierto retraso respecto a otros países europeos. Hacemos esta aproximación mediante un análisis teórico y un análisis empírico. El primero hace referencia a un breve y necesario estado del arte sobre esta cuestión. El análisis empírico se realizada sobre datos de Dialnet y Web of Science, sobre la evolución de las publicaciones sobre esta cuestión en publicaciones en castellano y en inglés. También se analizan datos sobre la presencia de comunicaciones acerca de movimientos sociales en congresos de Sociología y Ciencia Política. La parte cualitativa es un análisis de entrevistas semi-estructuradas a pioneros-as en este campo de conocimientos. Las conclusiones aluden a que el crecimiento del estudio de los movimientos sociales en España se ha visto amplificado por la normalización de la democracia y de la protesta y, sobre todo, a partir del ciclo de protesta del 15M como fenómeno sociológico de estudio internacional.
Juventudes latinas en España: identidades culturales, prácticas políticas y juvenicidio. Entrevista a Carles Feixa
Authors: Rebolledo Cortés Henry Steven
Published: December 2022

Las investigaciones recientes acerca de las juventudes están demostrando las luchas en que los y las jóvenes constituyen mundos de vida en resistencia a sociedades precarizadas. Esta entrevista es realizada a Carles Feixa, catedrático de Antropología Social en la Universitat Pompeu Fabra, Doctor por la Universidad de Barcelona, España y Honoris Causa por la Universidad de Manizales, Colombia.  En el presente trabajo, se presenta una entrevista realizada en el mes marzo de 2022, realizada en la visita a expertos en asuntos de juventud en Manizales, Colombia, en el marco de una investigación doctoral, para analizar la conformación de los procesos de construcción de identidades, prácticas políticas y culturales desde las juventudes latinoamericanas en territorios de España y Europa.
Unknown materials about Usein Abdulrefioglu Bodaninsky (1877–1938)
Authors:   Fevzi Yakubov Crimean Engineering and Pedagogical University, Kerimov Ismail A. ,   Marjani Institute of History of the Tatarstan Academy of Sciences
Published: December 2022

The materials discovered recently in the Russian State Library in Moscow are unknown to modern researchers of the activities of the founder of BIKAMZ A. Bodaninsky. In particular, information about the large funds that were issued to Bodaninsky by the Bakhchisaray vaqf “Tole” after graduating from the Tatar teacher`s school in Simferopol, which played a major role in his trip and training in Moscow at the Stroganov School of Technical Drawing. New in the article are also materials related to the appeals of U. Bodaninsky in 1916 to Taurida Governor and also “Society for Protection of Historical and Cultural Monuments” in Petrograd, related to the intentions of opening an ethnographic museum in Bakhchisaray. Also little known are the frequent trips of U. Bodaninsky in 1915–1916, when he created the “Society of Lovers of Art and Ethnography” from local youths which played an important role, including material, at the official opening the Bakhchisaray museum in1917, because all members of a large society annually contributed a certain fee to the activities of the museum.
New finds of Muslim tombstones of the 13th century on the territory of Stary Krym
Authors:   Marjani Institute of History of the Tatarstan Academy of Sciences, Useinov Memedulla A.
Published: December 2022

The article examines two Muslim tombstones found in 2021 during earthworks in the city of Stary Krym. The monuments have well-preserved inscriptions containing the names of the buried and the date – Rabi-ul avval 684 AH. =(1285). The tombstones date back to the early period of development of the Golden Horde city of Solkhat/Kirim and are the earliest Muslim tombstones in the Crimea that have survived to this day. Muslim tombstones dating back to the 13th century are a rather rare find for the Crimea, which indicates the value of the found specimens.
Features of administration of justice in the Crimean Khanate
Authors:   Fevzi Yakubov Crimean Engineering and Pedagogical University, Vaniev Eldar S.
Published: December 2022

The article analyzes the problems of functioning of judicial system in the Crimean Khanate. The law institute of the Crimean judges was an important component of the Crimean judicial system. Its principals and features of development are analyzed in the article. A brief historical review of the establishment of qadi institution in the Muslim legal system is carried out. The independence of the development of the Crimean judicial system is indicated, its internal structure is considered. It was found out that the structure consisted of three levels, similar to modern. The Crimean khan was endowed with a special set of judicial powers. It was revealed that the administration of the justice in the Crimean Khanate had a high level of organization, characterized by a strict procedural order of court hearings. The author makes hypothesis that the Crimean judicial system had also sectorial specialization similar to modern.
A Arte na Educação Básica: reflexões acerca da performance artística no contexto de práticas em arte no ensino médio
Authors: Souza Marco Aurelio da Cruz , Brisola Eduarda Cristina , Ricobom Carol Eduarda
Published: December 2022

O presente artigo resulta de reflexões sobre a prática do componente curricular Estágio em Dança no Ensino Médio, da 6ª fase da Licenciatura em Dança, da Fundação Universidade Regional de Blumenau/SC realizada com estudantes do 1º ano do ensino médio do Instituto Federal de Santa Catarina (IFSC), Campus Gaspar. A proposta do estágio foi trabalhar com a performance artística e como uma das avaliações desenvolver releituras de performances da artista Marina Abramović, das quais 8 foram contextualizadas nesse artigo. Temas como feminismo, lugar do corpo e empoderamento ganharam destaque nos trabalhos desenvolvidos. Foi perceptível o desenvolvimento da autonomia nos processos autorais dos estudantes.
Ação extensionista de teatro no ensino fundamental: reverberações na formação inicial de professores
Authors: Caldeira Leite Vanessa , Kemel Zanella Andrisa
Published: December 2022

O texto aborda sobre a trajetória de cinco anos do Projeto de Extensão “Vivências Teatrais em Escolas”, vinculado ao Curso de Teatro-Licenciatura, da Universidade Federal de Pelotas, que desenvolve oficinas de teatro com crianças e adolescentes dos anos finais do ensino fundamental, em uma escola pública de uma cidade do sul do Rio Grande do Sul. Apresenta o contexto social e cultural da cidade e como se deu a parceria universidade e escola. As reflexões tratam sobre a dinâmica do projeto, das aulas de teatro e das escolhas e estratégias metodológicas, do processo de criação coletiva e apreciação estética, dos avanços percebidos e dos desafios que a pandemia de Covid-19 trouxe para a continuação das ações desenvolvidas. Como aportes teóricos do trabalho realizado e que embasam esta escrita destacamos: Boal (2004), Ferreira (2006), Kischimoto (1993), Spolin (2004; 2005).  Ao final, refletimos sobre a interação dialógica entre a comunidade acadêmica e a sociedade, ao fomentar a arte e a cultura no espaço escolar e no município de Pedro Osório. E, a importância de projetos de extensão na formação inicial de professores, ao possibilitar a vivência dos conhecimentos no cotidiano da comunidade, reverberando em aprendizagens que se dão na escola como espaço de diálogo, experimentação e partilha de saberes.
Pandemia da Covid-19: o ensino remoto e o trabalho do professor de dança
Authors: Gabrielli Boaventura Michelle Aparecida , Batista Machado Aline Maria
Published: December 2022

O presente artigo busca apresentar a visão de professores de dança de escolas municipais da educação básica de João Pessoa-PB acerca de aspectos que precarizam suas condições de trabalho, especialmente, durante a pandemia da Covid-19. Esse trabalho foi realizado a partir de uma pesquisa qualitativa, fundamentada no Materialismo Histórico-Dialético e no método dialético para análise dos dados. Foram entrevistados 11 professores da área de dança que lecionam para os segmentos da Educação Infantil, Ensino Fundamental I e II e Educação de Jovens e Adultos, que ingressaram na rede pública municipal de ensino em 2015 a partir do concurso realizado pela Prefeitura Municipal de João Pessoa-PB (Edital nº 01/2013). Os resultados encontrados demonstraram o modo com que esses professores se entendem enquanto trabalhadores e como percebem aspectos da precarização em seu trabalho durante a pandemia. Portanto, se por um lado, os professores foram responsabilizados pelas falhas e insucessos das aulas remotas, por outro, eles próprios assumiram a responsabilidade em fazer com que o processo de ensino e aprendizagem em meio a pandemia funcionasse, buscando acolher os estudantes em meio a uma situação de restrições sociais e perdas humanas.
The efficacy and safety of single mite and double mite subcutaneous immunotherapy in children with allergic asthma
Authors: Fan Fang , Zhang Jiyan , Yang Min , Zhang Jin , Huang Xueshan , Qiu Jun , Chen Yanping
Published: December 2022

Background: Subcutaneous immunotherapy is an effective and safe
treatment for allergic asthma. However, there have been very few studies
about comparison of single mite vs double mite subcutaneous
immunotherapy. In this study, we aimed to evaluate the difference in
clinical efficacy and safety of subcutaneous immunotherapy with dust
mite allergen vaccines in children with allergic asthma.
Methods: This study is a retrospective and single-center study
performed from Jan 2019 to Jun 2022. A total of 124 children who were
grouped into single mite preparation group and double mite preparation
group. The efficacy scores, changes in pulmonary function and the
occurrence of adverse effects were compared between the 2 groups before
and after treatment. Results: The efficacy scores were
significantly decreased in all children with SCIT after 6 months
treatment, and the quality of life significantly improved compared with
those before treatment (P< 0.01). After 2 years of treatment,
double mite preparation were statistically significant improved in PEF,
FEV1, and FVC(P<0.05); single mite preparation were better for
CS, VAS improvement(P<0.05); single mite preparation has
higher rate of local and systemic adverse reactions(P < 0.05).
Conclusion: Both preparations can achieve significant efficacy
and safety in children with allergic asthma. The short-term improvement
of asthma symptoms was more significant with the double mite
preparation, but the single mite preparation was more effective as the
treatment course was extended. Single mite preparation was more
effective in improving the symptoms of rhinitis. Double mite preparation
had a better safety and was better for lung function improvement.
In Silico Designing and Optimization of the Anti-EGFR Scaffolds by CDRs-Grafting Technique
Authors: Gargari Seyed Latif Mousavi , Adriani Razieh Rezaei
Published: December 2022

Monoclonal antibodies are attractive therapeutic agents in a wide range
of human disorders that bind specifically to their target through their
complementary-determining regions (CDRs). Small proteins with
structurally preserved CDRs are promising alternatives to antibodies. In
this study, we presented new antibody mimetics against colorectal cancer
marker epidermal growth factor receptor (EGFR) created by CDRs grafting
technique. Ten potential graft acceptor sites that efficiently
immobilise the grafted CDR loops were selected from three small protein
scaffolds by computational identification. The three most involved CDR
loops in antibody-receptor interactions extracted from panitumumab
monoclonal antibody against domain III of EGFR (EGFR DIII) crystal
structure were then grafted to the selected scaffolds through the loop
randomization technique. The combination of three CDR loops and 10
grafting sites revealed that three of the 36 combinations showed
specific binding to EGFR DIII by binding energy calculation. Thus, the
present strategy and selected small protein scaffolds are promising in
designing new binders against EGFR with high binding energy.
Fixed-time Observer-based Controller for the Human-Robot Collaboration with Interaction Force Estimation
Authors: Abadi Ali Soltani Sharif , Hosseinabadi Pooyan Alinaghi , Hameed Ayesha , Ordys Andrew , Pierscionek Barbara
Published: December 2022

An exoskeleton robot is a sample of a wearable robot. One of the most
critical challenges in developing wearable robots is the application of
the interactive force between human and robot. Force sensors need to be
placed on the robot. Consideration in using these sensors needs to be
given to factors such as cost, noise, and weight. One way that can be
used to help with the operation of the exoskeleton is to support the
sensors with observers. This study will estimate the interactive force
applied to a human arm model and the exoskeleton robot. The Sliding Mode
Control (SMC) method will be employed to design a chattering-free robust
fixed-time controller and observer, for estimating the states of the
human arm and exoskeleton robot. Utilising this information from state
observers, the interactive force is estimated. The state observer and
the controller work together in real-time (online estimation). The
Lyapunov theory is used to show the fixed-time stability analysis of the
controller and the observer. Numerical simulation with three scenarios
demonstrates the performance of the proposed design.
Guest Editorial: Grid Forming Converters Placement and Utilisation to Enhance Transmission and Distribution Performances Under High Penetration of Inverter-Based Resources
Authors: Badrzadeh Babak , Matevosyan Julia , Emin Zia , Lu Chao
Published: December 2022

Power systems around the world are rapidly transitioning to much higher
shares of inverter-based resources (IBRs) with few synchronous
generators remaining online. IBRs and synchronous generators have
fundamentally different dynamic performance characteristics resulting in
a difference in the overall power system dynamic performance. IBRs are
generally more flexible and controllable than synchronous generators,
however at the same time exhibit significantly more complex control
systems. Furthermore, new and emerging capabilities are being developed
progressively and in particular the so-called grid-forming inverters.
Grid-forming inverters (GFM) offer several new capabilities not
previously possible with conventional grid-following inverters (GFL).
However, they are not well understood currently when applied in a mega
scale and moving forward when they will likely take over the role
synchronous generators have been performing for several decades as the
workhorse of system security support. Key questions currently in the
technical community include the extent to which GFM shall be similar or
different to each of the synchronous machines and conventional GFL, and
how various control strategies can assist in maximising the grid support
capabilities sought and minimise or ideally eliminate any adverse
impacts. The objective of this special issue is to provide insights into
some of these unknowns.
Cost/Benefit Analysis for Installation of Capacitor and Distributed Generator with Network Reconfiguration considering Load Growth and Variations
Authors: Gopisetti Dr Manikanta , Mani Ashish
Published: December 2022

The load demand at distribution network (DN) is increasing day by day
due to increase in industrial, commercial, municipal, residential and
irrigation needs. In order to meet the increased load demand in DN,
distributed energy resources i.e., Distributed Generators (DG),
Capacitors and Network reconfiguration are used as alternative
solutions. In this paper, an attempt has been made to maximize the
economic benefits in distribution system with installation of DGs,
Capacitors and Network reconfiguration by simultaneously optimizing the
location, size, switching configuration while taking into account, the
load growth and the variations in load in DN also. Optimal location and
capacity of DG and Capacitor is a difficult non differentiable
combinatorial optimization problem. Adaptive Quantum inspired
evolutionary Algorithm (AQiEA) has been used to solve the difficult non
differentiable, combinatorial optimization problem. The effectiveness of
AQiEA is tested with a benchmark test bus system i.e., 33 bus system. In
this study, two different cases are considered to test the effectiveness
of proposed algorithm. Seven different Scenarios are considered to
analyse the losses incurred in the system with variation in load in
first case. The effectiveness of the proposed algorithm as compared with
other algorithm is demonstrated on the other case.
A Semi-automatic 3D mesh segmentation based on Cross-Boundary strokes
Authors: Lian Jiguang , Li Haisheng , Li Nan , Wang Xiaochuan
Published: December 2022

3D segmentation has been a hot spot in numerical geometry processing.
But the accuracy of the segmentation methods can be easily affected by
the types of models because their sensitivity to different models is
uneven. To address this problem, we propose a semi-automatic 3D mesh
segmentation algorithm based on harmonic field. Firstly, our algorithm
utilizes the strokes of users as constraints on the harmonic field of
the mesh surface. Secondly, a smooth harmonic field based on Laplacian
operator and Poisson equation is introduced. Through the generated
harmonic field, the correct weights are selected to further fit the
geometric characteristics of the grid. Afterwards, we find a set of most
suitable isolines on the harmonic field as the segmentation path.
Finally, a mesh density enhancement method is designed, which optimizes
sub-graphs after segmentation. Experimental results demonstrate that the
effectiveness of our proposed algorithm. Moreover, the semi-automatic 3D
mesh segmentation algorithm can better understand the intention of
users.
Férfi betegek STD-mintáiból izolált Staphylococcus aureus törzsek epidemiológiája és antibiotikum érzékenysége (2008-2017)
Authors: Gajdács Márió
Published: December 2022

Bevezetés: A reproduktív szervek bakteriális fertőzései jelentős morbiditási tényezőnek és a meddőség egyik leggyakoribb okának számítanak férfiakban. Egyre több tanulmány számol be a Staphylococcus aureus egyre növekvő jelentőségéről urológiai kórképekben, azonban kevés adattal rendelkezünk az izolátumok érzékenységéről. Anyag és módszer: A kutatás során SZTE Klinikai Mikrobiológiai Diagnosztikai Intézet STD laboratóriumába 2008. 01. 01. és 2017. 12. 31. között, férfi betegektől érkezett mintákból kitenyészett S. aureus izolátumok retrospektív mikrobiológiai elemzése történt. Eredmények: A vizsgálati periódus alatt 85 S. aureus izolátum került kitenyésztésre, az érintett betegek átlagéletkora 37±14 év (tartomány: 17–90) volt. A 10 éves periódus alatt 2 MRSA-izolátumot detektáltunk. Az izolátumok érzékenysége közel 100%-os volt a vizsgált antibiotikumokra, kivéve a fluorokinolonokat (~90%) és a makrolidokat (~75- 80%). Következtetés: A S. aureus viszonylag ritkán előforduló izolátum férfi betegek STD-mintáiban, azonban magas fokú patogenitása miatt jelentősége nem elhanyagolható.
Az Uro-Vaxom szerepe a hólyaghurut kezelésében és megelőzésében
Authors: Magyar András , Tenke Péter
Published: December 2022

Bevezetés: A növekvő bakteriális rezisztencia miatt a visszatérő cystitis megelőzésében a nem antibiotikum-alapú módszerek alkalmazása rendkívül fontos. Ezek közé tartozik az Uro-Vaxom liofilizált Escherichia coli baktérium lizátumot tartalmazó készítménnyel (OM-89) történő immunoaktív profilaxis. Visszatérő cystitis megelőzésében hatékonyságát több tanulmány elemezte. Célunk ezen vizsgálatok eredményeinek összefoglalása. Módszerek: A rendelkezésre álló közleményeket PubMed-en történő kereséssel és a témában leközölt összefoglaló közlemények alapján gyűjtöttük össze a következő szempontok szerint: 1) a kezelés hatásainak vizsgálata, 2) alkalmazása visszatérő hólyaghurut megelőzésében 3) kialakuló immunitás több kórokozóval szemben, 4) adagolás időzítése, 5) kezelési, immunizálási sémák. Eredmények: Az Uro-Vaxom profilaxis, kórokozótól függetlenül, 6 hónap alatt 36%-kal csökkenti a visszatérő heveny hólyaghurutos fellángolások arányát, ezáltal mérsékelhető az antibiotikum-felírások száma. Következtetések: A visszatérő hólyaghurut nem antibiotikum-alapú megelőzésében alkalmazható készítmények közül az Uro-Vaxom rendelkezik a legerősebb tudományos alapokkal. Intermittáló alkalmazásával hatékonysága tovább növelhető.
Rosszindulatú vesedaganat eltávolítása myasthenia gravis miatt kezelt betegnél
Authors: Pénzes Erzsébet , Nyirády Péter
Published: December 2022

Bevezetés: A vese eltávolítása fontos része az onkológiai kezelésnek rosszindulatú vesedaganat esetén, emiatt a társbetegségek, nem jelenthetnek akadályt a műtétnek. Myasthenia gravis egy autoimmun betegség, amely során acetilkolin-receptor-ellenes antitestek jelennek meg a neuromuszkuláris junkción, okuláris, bulbaris, légzési tüneteket okozhatnak. Esetismertetés: A 66 éves férfi betegnél 13 éve gyógyszerrel sikeresen kezelt generalizált betegség igazolódott. Az elhúzódó műtét, az altatószerek súlyos állapotot idézhetnek elő. Az aneszteziológusnak, gondolnia kell a perioperatív légzési nehézségre, amely intenzív osztályos ellátást igényel. Megbeszélés: A vesedaganat miatt végzett nephrectomia nemcsak az életminőséget javítja, hanem a későbbi onkológiai kezelés sikerét is megalapozza, ezért is fontos a kísérőbetegségek pontos ismerete, az anesztéziai és a műtéti utáni ellátás összhangja.
Uncertainty and bank funding liquidity risk in Vietnam
Authors: Dang Van , Nguyen Hoang
Published: December 2022

This paper examines the impact of uncertainty on bank funding liquidity risk.
Based on a sample of Vietnamese commercial banks from 2007 to 2019, we show
evidence that micro uncertainty in the banking sector leads to higher
funding liquidity risk, as proxied by lower deposit ratios. Additional
analyses reveal that this nexus widely depends on bank heterogeneity. More
precisely, various bank-specific forces that improve banks? financial
strength (i.e., an increase in bank return, loan quality, capitalization,
liquid assets, and bank size) tend to mitigate the adverse impact of
uncertainty on bank funding liquidity risk. Our findings are robust to
changes in multiple combinations of regressors, different key bank-level
variables to calculate the dispersion of shocks as banking uncertainty
measures, and alternative econometric approaches.
Weyl type theorems for a class of operator matrices
Authors: Zhang Weihong , Hai Guojun , Chen Alatancang
Published: December 2022

It is well known that not all operators satisfy Weyl type theorems simultaneously. In this paper, we denote an operator matrix and consider how eight Weyl type theorems hold for it when certain entry operators satisfy Weyl type theorems. Moreover, we characterize its spectral structure. Finally, the relevant conclusions are promoted to infinite dimensional Hamilton operator.
A new variant of Hildebrandt’s theorem for the Weyl spectrum in Banach spaces
Authors: Charfi Salma , Rahali Sassia , Walha Ines
Published: December 2022

The main purpose of this paper is to establish a new variant of the
Hildebrandt?s theorem for the Weyl spectrum in a separable Banach space.
This theorem asserts that the convex hull of the Weyl spectrum of an operator
T is equal to the intersection of the Weyl numerical spectra of operators
that are similar to T.
Exterior square graph of a finite group
Authors: Zameni M. , Niroomand P. , Alizadeh Sanati , Parvizic M.
Published: December 2022

In this paper, we define the exterior square graph ?E?G which is a graph
associated to a non-cyclic finite group with the vertex set G\Z?(G), where
Z?(G) denotes the exterior center of G, and two vertices x and y are joined
whenever x?y=1, where ? denotes the operator of non-abelian exterior
square. We investigate how the group structure can be affected by
completeness, regularity and bipartition of this graph.
Nearest southeast submatrix that makes two prescribed eigenvalues
Authors: Nazari Alimohammad , Nezami Atiyeh
Published: December 2022

Given four complex matrices A, B, C and D where A ? Cn?n and D ? Cm?m and
given two distinct arbitrary complex numbers ?1 and ?2, so that they are not
eigenvalues of the matrix A, we find a nearest matrix from the set of
matrices X ? Cm?m to matrix D (with respect to spectral norm) such that
the matrix A B C X ! has two prescribed eigenvalues ?1 and ?2.
Nephi’s Convincing of Christ through Chiasmus: Plain and Precious Persuading from a Prophet of God
Authors: Sloan David E.
Published: December 2022

One of the principal themes of Nephi’s writings on the small plates is his desire to convince others of Christ. A second, related theme is his desire to write plain and precious things on those plates. Some of the most plain and precious writings of Nephi are those instances in which he used the name Christ in chiasmus or other forms of poetry. Perhaps more than any other portion of his words, Nephi intended these plain and precious writings to convince both Jew and gentile that Jesus is the Christ, the one true Messiah.
Therapeutic Exosomes as Novel Treatment for Ovarian Cancer
Authors:   , Donnelly Claire A.
Published: December 2022

Ovarian cancer (OC) has the highest mortality rate of all gynecological cancers, with a low 5-year survival rate. This is in part due to resistance to chemotherapy drugs and recurrence, which causes OC treatments to become inadequate. Exosomes are a type of extracellular vesicle (EV), along with microvesicles and apoptotic bodies. Exosomes act as key mediators of intercellular communication. This leads to the involvement of exosomes in many normal physiological processes including immune responses. However, exosomes derived from tumour cells are implicated in pathological processes, such as cancer progression and metastasis. This study evaluated the role of tumour derived exosomes in OC. This included assessing their biomarker potential. In contrast, non-tumour derived exosomes were evaluated to determine therapeutic ability.
Evaluation of transport system configuration by efficiency indicators
Authors:   Rzeszow University of Technology, Mateichyk Vasyl , Śmieszek Miroslaw ,   Rzeszow University of Technology, Kostian Nataliia ,   Cherkasy State Technological University
Published: December 2022

The study is devoted to the process of evaluating the efficiency of the transport system in terms of urban mobility. The approach is based on the use of a system of performance indicators using neurocomputer technologies. Generalized models for obtaining a vector of performance indicators and an integral performance indicator in the form of computer neural networks are proposed. It is shown that to record the fact that the indicator values fall to the threshold and below, it is enough to use a neural network built on perceptron neurons. The multi-layered model for determining the integral indicator allows assessing the importance of individual indicators in the system of monitoring the efficiency of a given configuration of the transport system. An experimental study of twenty-five states of the transport system of various configurations in the cities of Poland and Ukraine was carried out. The key indicators of the system's efficiency are determined, namely, the energy efficiency indicator of the vehicle as a system element, the environmental indicator and the traffic safety indicator. Based on the results of the experimental study, a neural network structure is proposed for evaluating the energy efficiency of given configurations of the transport system. For the purpose of training and testing the obtained network, the procedure of adjusting the threshold value of the activation function and normalizing the values of the input parameters array of the transport system was used. The constructed network was implemented using Visual Studio 2019 using the C++ language. The network was adjusted to determine the energy efficiency estimate with a given accuracy by replacing the perceptron neuron with a regular one with a sigmoidal activation function. The random nature of the choice of the configuration and the initial values of the weighting factors made it possible to obtain a model with an accuracy of implementation on the control sample in the range from 90 to 98.7% at a learning rate of 0.1.