bluuebunny/crossref_metadata_2025 huggingface dataset:
Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis
Authors: Berg Hege F. , Hjelmeland Marta Espevold , Lien Hilde , Espedal Heidi , Fonnes Tina , Srivastava Aashish , Stokowy Tomasz , Strand Elin , Bozickovic Olivera , Stefansson Ingunn M. , Bjørge Line , Trovik Jone , Haldorsen Ingfrid S. , Hoivik Erling A. , Krakstad Camilla
Published: July 2021

Background

A major hurdle in translational endometrial cancer (EC) research is the lack of robust preclinical models that capture both inter- and intra-tumor heterogeneity. This has hampered the development of new treatment strategies for people with EC.

Methods

EC organoids were derived from resected patient tumor tissue and expanded in a chemically defined medium. Established EC organoids were orthotopically implanted into female NSG mice. Patient tissue and corresponding models were characterized by morphological evaluation, biomarker and gene expression and by whole exome sequencing. A gene signature was defined and its prognostic value was assessed in multiple EC cohorts using Mantel-Cox (log-rank) test. Response to carboplatin and/or paclitaxel was measured in vitro and evaluated in vivo. Statistical difference between groups was calculated using paired t-test.

Results

We report EC organoids established from EC patient tissue, and orthotopic organoid-based patient-derived xenograft models (O-PDXs). The EC organoids and O-PDX models mimic the tissue architecture, protein biomarker expression and genetic profile of the original tissue. Organoids show heterogenous sensitivity to conventional chemotherapy, and drug response is reproduced in vivo. The relevance of these models is further supported by the identification of an organoid-derived prognostic gene signature. This signature is validated as prognostic both in our local patient cohorts and in the TCGA endometrial cancer cohort.

Conclusions

We establish robust model systems that capture both the diversity of endometrial tumors and intra-tumor heterogeneity. These models are highly relevant preclinical tools for the elucidation of the molecular pathogenesis of EC and identification of potential treatment strategies.
Carbolong chemistry: nucleophilic aromatic substitution of a triflate functionalized iridapentalene
Authors: Li Jinhua , Lu Zhengyu , Hua Yuhui , Chen Dafa , Xia Haiping
Published: July 2021

The nucleophilic aromatic substitution (SNAr) reactions of a triflate functionalized iridapentalene with C-, N-, O- and S-centred nucleophiles afforded a series of irida–carbolong derivatives.
N-Hydroxyphthalimide-catalyzed chemoselective intermolecular benzylic C–H amination of unprotected arylalkanols
Authors: Shibuya Masatoshi , Orihashi Takayuki , Li Yamei , Yamamoto Yoshihiko
Published: July 2021

1,1,1,3,3,3-Hexafluoropropan-2-ol deactivates the C–H bonds proximal to a hydroxy group, enabling the chemoselective benzylic C–H amination of unprotected arylalkanols.
Imaging intramolecular hydrogen migration with time- and momentum-resolved photoelectron diffraction
Authors: Ota Fukiko , Abe Shigeru , Hatada Keisuke , Ueda Kiyoshi , Díaz-Tendero Sergio , Martín Fernando
Published: July 2021

Imaging ultrafast hydrogen migration with few- or sub-femtosecond time resolution is a challenge for ultrafast spectroscopy due to the lightness and small scattering cross-section of the moving hydrogen atom.
The facile preparation of solid-state fluorescent carbon dots with a high fluorescence quantum yield and their application in rapid latent fingerprint detection
Authors: Wang Hai-Jiao , Hou Wan-Yi , Kang Jing , Zhai Xin-Yu , Chen Hong-Li , Hao Yong-Wei , Wan Guo-Yun
Published: July 2021

Novel solid-state fluorescent carbon dot powder with a high PLQY was prepared and successfully applied in rapid latent fingerprint imaging.
Single crystals of undoped Li2WO4 and Li2W1−0.0125Mo0.0125O4: formation enthalpies, heat capacity in the temperature range 320–997 K
Authors: Matskevich Nata I. , Shlegel Vladimir N. , Semerikova Anna N. , Samoshkin Dmitrii A. , Grigorieva Veronika D. , Stankus Sergei V. , Kuznetsov Vitalii A. , Ponomareva Sofiya A. , Zaitsev Valerii P. , Novikov Andrei Yu.
Published: July 2021

Li2WO4 single crystal was grown using the low-temperature-gradient Czochralski technique. Formation enthalpy, lattice enthalpy of Li2WO4 and heat capacity of Li2W1−0.0125Mo0.0125O4 (T = 320–997 K) were measured.
Routine high-precision Nd isotope analyses: an optimized chromatographic purification scheme
Authors: Hyung Eugenia , Tissot François L. H.
Published: July 2021

We present an optimized α-HIBA column chromatography method for Nd for high-precision isotope analyses (±2–5 ppm). It produces consistently high yields (>95%) and extremely good separation of Ce, Pr and Sm from Nd.
Visible-light-responsive lanthanide coordination polymers for highly efficient photocatalytic aerobic oxidation of amines and thiols
Authors: An Shuyi , Guo Zhifen , Liu Xin , Che Yan , Xing Hongzhu , Chen Peng
Published: July 2021

Photoinduced activation of oxygen by visible-light-responsive CPs via electron/energy transfer and its roles on aerobic oxidation of amines and thiols.
All-carbocycle hydrocarbon thermosets with high thermal stability and robust mechanical strength for low-kinterlayer dielectrics
Authors: Feng Yudi , Jin Ke , Guo Jia , Wang Changchun
Published: July 2021

Two kinds of hydrocarbon precursors were synthesized and cured at elevated temperatures to give cross-linked all-aliphatic/aromatic-ring polymers with a low dielectric constant for next-generation interlayer dielectrics.
Physical conditions in the warped accretion disk of a massive star
Authors: Sanna A. , Giannetti A. , Bonfand M. , Moscadelli L. , Kuiper R. , Brand J. , Cesaroni R. , Caratti o Garatti A. , Pillai T. , Menten K. M.
Published: July 2021

Young massive stars warm up the large amount of gas and dust that condenses in their vicinity, exciting a forest of lines from different molecular species. Their line brightness is a diagnostic tool of the gas’s physical conditions locally, which we use to set constraints on the environment where massive stars form. We made use of the Atacama Large Millimeter/submillimeter Array at frequencies near 349 GHz, with an angular resolution of 0′′.1, to observe the methyl cyanide (CH3CN) emission which arises from the accretion disk of a young massive star. We sample the disk midplane with twelve distinct beams, where we get an independent measure of the gas’s (and dust’s) physical conditions. The accretion disk extends above the midplane, showing a double-armed spiral morphology projected onto the plane of the sky, which we sample with ten additional beams: Along these apparent spiral features, gas undergoes velocity gradients of about 1 km s−1 per 2000 au. The gas temperature (T) rises symmetrically along each side of the disk, from about 98 K at 3000 au to 289 K at 250 au, following a power law with radius R−0.43. The CH3CN column density (N) increases from 9.2 × 1015 cm−2 to 8.7 × 1017 cm−2 at the same radii, following a power law with radius R−1.8. In the framework of a circular gaseous disk observed approximately edge-on, we infer an H2 volume density in excess of 4.8 ×109 cm−3 at a distance of 250 au from the star. We study the disk stability against fragmentation following the methodology by Kratter et al. (2010, ApJ, 708, 1585), which is appropriate under rapid accretion, and we show that the disk is marginally prone to fragmentation along its whole extent.
Comparison of space weathering spectral changes induced by solar wind and micrometeoroid impacts using ion- and femtosecond-laser-irradiated olivine and pyroxene
Authors: Chrbolková Kateřina , Brunetto Rosario , Ďurech Josef , Kohout Tomáš , Mizohata Kenichiro , Malý Petr , Dědič Václav , Lantz Cateline , Penttilä Antti , Trojánek František , Maturilli Alessandro
Published: July 2021

Context.Space weathering is a process that changes the surface of airless planetary bodies. Prime space weathering agents are solar wind irradiation and micrometeoroid bombardment. These processes alter planetary reflectance spectra and often modify their compositional diagnostic features.

Aims.In this work we focused on simulating and comparing the spectral changes caused by solar wind irradiation and by micrometeoroid bombardment to gain a better understanding of these individual space weathering processes.

Methods.We used olivine and pyroxene pellets as proxies for planetary materials. To simulate solar wind irradiation we used hydrogen, helium, and argon ions with energies from 5 to 40 keV and fluences of up to 1018particles cm−2. To simulate micrometeoroid bombardment we used individual femtosecond laser pulses. We analysed the corresponding evolution of different spectral parameters, which we determined by applying the Modified Gaussian Model, and we also conducted principal component analysis.

Results.The original mineralogy of the surface influences the spectral evolution more than the weathering agent, as seen from the diverse evolution of the spectral slope of olivine and pyroxene upon irradiation. The spectral slope changes seen in olivine are consistent with observations of A-type asteroids, while the moderate to no slope changes observed in pyroxene are consistent with asteroid (4) Vesta. We also observed some differences in the spectral effects induced by the two weathering agents. Ions simulating solar wind have a smaller influence on longer wavelengths of the spectra than laser irradiation simulating micrometeoroid impacts. This is most likely due to the different penetration depths of ions and laser pulses. Our results suggest that in some instances it might be possible to distinguish between the contributions of the two agents on a weathered surface.
The origin of X-ray emission in 3CRR sources: Hints from mid-infrared Spitzer observations
Authors: Li Shuang-Liang , Gu Minfeng
Published: July 2021

Aims. Whether X-ray emission in radio-loud (RL) active galactic nuclei (AGNs) originates from disk coronae or jets is still under debate. For example, the positive relationships in radio-quiet AGNs (such as the optical to X-ray spectral index αOX and Eddington ration λO as well as the X-ray photon index Γ and λO) are not detected in RLAGNs. We intend to further investigate this issue in this work.

Methods. A sample of 27 luminous sources (including 16 quasars and 11 high-excitation radio galaxies) was selected from the 3CRR catalog to reinvestigate the origin of X-ray emission in RLAGNs, where the X-ray and mid-infrared fluxes are observed by Chandra/XMM-Newton and Spitzer, respectively.

Results. It is found for the first time that there is a significant relationship between the mid-infrared to X-ray spectral index αIX and λIR for whole sample, while there is no relationship between αOX and λO in quasars. There are strong positive relationships between both LR − LX and LUV − LX panels, which can be well fitted by the disk-corona model. However, there is no significant relationship between Γ and λIR. The possible reason is related to the effects of the large-scale magnetic field in RLAGNs.

Conclusions. We suggest that the X-ray emission in high-excitation RLAGNs originates from a disk-corona system.
A MUSE spectro-imaging study of the Th 28 jet: Precession in the inner jet
Authors: Murphy A. , Dougados C. , Whelan E. T. , Bacciotti F. , Coffey D. , Comerón F. , Eislöffel J. , Ray T. P.
Published: July 2021

Context. Th 28 is a Classical T Tauri star in the Lupus 3 cloud that drives an extended bipolar jet. Previous studies of the inner jet identified signatures of rotation around the outflow axis, a key result for theories of jet launching. Thus this is an important source in which to investigate the poorly understood jet launching mechanism.

Aims. In this study we investigate the morphology and kinematics of the Th 28 micro-jets, with the aim of characterising their structure and outflow activity, using optical integral-field spectroscopy observations obtained with VLT/MUSE.

Methods. We use spectro-imaging and position–velocity maps to investigate the kinematic and morphological features of the jet and to obtain a catalogue of emission lines in which the jet is visible. A Lucy-Richardson deconvolution procedure is used to differentiate the structure of the inner micro-jet region in selected emission lines. Spatial profiles extracted perpendicular to the jet axis are fitted to investigate the jet width, opening angle, and the evolution of the jet axis.

Results. We confirm the previously identified knot HHW2 within the red-shifted jet and identify three additional knots in each lobe for the first time. We also find [O III]λ5007 emission from the blue-shifted micro-jet, including the knot closest to the star. Proper motions for the innermost knots on each side are estimated to be 0′′.35 yr−1 and 0′′.47 yr−1 for the red- and blue-shifted jets, respectively. Based on this we show that new knots are ejected on an approximate timescale of 10–15 yr. Gaussian fitting to the jet axis centroids shows a point-symmetric wiggle within the inner portion of both micro-jets, indicating precession of the jet. We use the jet shape to measure a precession period of 8 yr, with a half-opening angle β < 0.6°. This precession may provide an alternative explanation for the rotation signatures previously reported.

Conclusions. We find that these parameters are compatible with precession due to a brown dwarf companion orbiting at a separation of ≤0.3 au. Further observations with higher spatial resolution may help to clarify the source of this precession.
Oscillations in the line-of-sight magnetic field strength in a pore observed by the GREGOR Infrared Spectrograph (GRIS)
Authors: Nelson C. J. , Campbell R. J. , Mathioudakis M.
Published: July 2021

Context. Numerous magnetohydrodynamic oscillations have been reported within solar pores over the past few decades, including in line-of-sight (LOS) velocities, intensities, and magnetic field strengths.

Aims. Our aim is to identify whether high-amplitude oscillations in the LOS magnetic field strength can be detected within a pore located in Active Region 12748 and to investigate which physical mechanisms could be responsible for them.

Methods. A solar pore was observed on 1 September 2019 using the GREGOR Infrared Spectrograph instrument for around one hour. Full-Stokes vectors were sampled in a 37 Å window containing the Fe I 15 648.52 Å line (effective Landé g factor of 3). The LOS magnetic field strength was inferred using the strong-field approximation. Additionally, the Stokes Inversion based on Response functions code was used to gain a more complete understanding of the physical properties of the solar atmosphere at the locations of these oscillations.

Results. Oscillations of more than 100 G are observed in the LOS magnetic field in the period window between 600 and 1272 s at three localised (> 1″2) regions. These oscillations have coherence across individual regions, indicating that jitter cannot account for their occurrence. Longer-period amplitude variations, amplitudes over 200 G, are also detected, but they have periods outside of the cone-of-influence. Numerical inversions confirm both oscillations in the LOS magnetic field strength at optical depths of around log τ5000 = −0.5 (potentially caused by compression) and other effects (e.g. changes in the optical depth or the inclination of the magnetic field) may account for these changes.

Conclusions. The oscillations in the separations of the Stokes-V lobes of the 15 648.52 Å line appear to be solar in nature. Future work will be required to understand whether these are truly oscillations in the magnetic field strength at a specific depth in the solar atmosphere or whether other effects are responsible for these signatures.
Revisiting neutron starquakes caused by spin-down
Authors: Rencoret Javier A. , Aguilera-Gómez Claudia , Reisenegger Andreas
Published: July 2021

Context. Pulsars show a steady decrease in their rotational frequency, occasionally interrupted by sudden spin-ups called glitches, whose physical origin is still a mystery. One suggested explanation for at least the small glitches are starquakes, that is, failures of the solid neutron star crust, in which the progressive reduction in the centrifugal force deforms the star, stressing the solid until it breaks. This produces a spin-up, dissipating energy inside the star.

Aims. We explore this suggestion by analyzing a mostly analytical model in order to understand the possible consequences of starquakes, particularly whether they can explain at least the small glitches.

Methods. We analyze the deformations and strains produced by the decreasing centrifugal force, modeling the neutron star with a fluid core and a solid crust, each with uniform density and with the core possibly denser than the crust, as a simple approximation to the strong density gradient present in real neutron stars.

Results. The deformation of a star with very different densities in the core and crust is qualitatively different from the previously studied case of equal densities. The former more closely resembles the behavior of a fluid star, in which the core-crust interface is a surface of constant gravitational plus centrifugal potential.

Conclusions. Regardless of the uncertain breaking strain, the glitch activity in this model is several orders of magnitude smaller than observed, even if only small glitches are considered. For a large breaking strain, suggested by simulations, glitches due to starquakes could be roughly of the correct size but much less frequent than observed glitches. The energy released in each such glitch is much larger than in the standard model of angular momentum transfer from a faster rotating superfluid in the inner crust. On the other hand, we cannot rule out that the heating produced by small starquakes could trigger glitches by allowing neutron superfluid vortices to move. We also confirm that stresses in the neutron star crust can in principle support an ellipticity much larger than some observational upper limits from pulsar timing and continuous gravitational wave searches.
Non-intrusive double-greedy parametric model reduction by interpolation of frequency-domain rational surrogates
Authors: Nobile Fabio , Pradovera Davide
Published: July 2021

We propose a model order reduction approach for non-intrusive surrogate modeling of parametric dynamical systems. The reduced model over the whole parameter space is built by combining surrogates in frequency only, built at few selected values of the parameters. This, in particular, requires matching the respective poles by solving an optimization problem. If the frequency surrogates are constructed by a suitable rational interpolation strategy, frequency and parameters can both be sampled in an adaptive fashion. This, in general, yields frequency surrogates with different numbers of poles, a situation addressed by our proposed algorithm. Moreover, we explain how our method can be applied even in high-dimensional settings, by employing locally-refined sparse grids in parameter space to weaken the curse of dimensionality. Numerical examples are used to showcase the effectiveness of the method, and to highlight some of its limitations in dealing with unbalanced pole matching, as well as with a large number of parameters.
Radiological protection challenges facing business activities affected by a nuclear accident: some lessons from the management of the accident at the Fukushima-Daiichi Nuclear Power Plant
Authors: Schneider T. , Lochard J. , Maître M. , Ban N. , Croüail P. , Gallego E. , Homma T. , Kai M. , Lecomte J.-F. , Takamura N.
Published: July 2021

Lessons from the Fukushima-Daiichi nuclear power plant accident emphasize the difficulties for restoring the socio-economic activities in the affected areas. Among them, a series of radioligical protection challenges were noted, in particular concerning the protection of employees, the securing of the production and the guarantee provided to consumers of the radiological monitoring of products to restore their confidence. Based on case studies reporting the experience of employers deploying their activities in affected areas, an analysis of these radiological protection challenges has been performed. Characterizing the radiological situation was not always straightforward for the managers. With the help of radiological protection experts, protective actions have been identified and specific efforts have been devoted to provide information to employees and their families helping them to make their own judgement about the radiological situation. Respecting the decisions of employees and developing a radiological protection culture among them have proved to be efficient for restoring the business activities. Continuing or restoring the production not always manageable. It requires to develop dedicated radiological monitoring processes to ensure the radiological protection of workers and the quality of the production. Re-establishing the link with the consumers and organising the vigilance on the long-term were necessary for companies to maintain their production or develop new ones. Deploying a socio-economic programme for ensuring the community resilience in affected areas requires the adoption of governance mechanisms respecting ethical values to ensure the overall objective of protecting people and the environment against the risks of ionizing radiation and contributing to provide decent living and working conditions to the affected communities. It is of primary importance to rely on the involvement of local communities in the elaboration and deployment of the socio-economic activities with due considerations for ensuring the integrity of the communities, and respecting their choices.
Formation indicators of strategic actions for oil and gas corporations within the framework of sustainable development concept
Authors: Lobova Elena , Zhukovskaya Svetlana , Taskaeva Alyona , Semina Lyudmila
Published: July 2021

Current trends in the global practice of forming sustainable development goals indicate that striving for innovative development is associated not only with investment activities, but also with tightening of environmental sanctions across the entire vertical of production and sales processes. Leading companies in the Russian oil and gas sector are prominent representatives of the industry and they shape their strategies in accordance with the UN Sustainable Development Goals. A study of the state of 6 companies of the oil and gas complex, which occupy stable positions in the markets of petroleum products and gas, is conducted in this paper. For the analysis, a methodology was chosen that covers the main directions in achieving the sustainable development goals: investment and innovation in technology, economic, social and environmental development. The materials of annual and consolidated reports on social, environmental and innovative development, the program of socio-economic and environmental development for 2015-2019 served as the information base for the formation of a sample of statistical indicators. The use of the benchmarking method made it possible to rank enterprises, find identity criteria, and evaluate possible strategic actions of oil and gas enterprises in achieving the integrated parameter of the Sustainable Development Index. On the basis of the obtained calculations, it is possible to form action strategies in the direction of "best practices" and adapt the worked out development programs relative to the general trend of achieving sustainable development of the oil and gas complex.
Dynamics of competitive forms of social partnership and their management in modern Russian society
Authors: Levchenko Valery
Published: July 2021

The author proposes to consider the process of optimization of social partnership management with regard to its competitive forms, relying on fairly representative and fairly numerous results of specific sociological studies carried out over more than three decades. The structure of competitive forms of social partnership and its changes over several decades in modern Russian society are analyzed.The main determinants defining the development of competitive forms of social partnership are presented. The main consequences (effects) of various competitive forms of social partnership for the productivity of activities, interpersonal relations and personal development are revealed.In particular, it is found that the strongest positive effect on practically all aspects of human life is provided by cooperative forms of social partnership and passive forms of competitiveness and individualism have the greatest negative effect. It is proposed to use the revealed patterns of competitive forms of social partnership in order to optimize management both in the system of social partnership and social interaction in general.
Theoretical aspects of problem solution in production systems
Authors: Borovik Vitaly Sergeevich , Skorobogatchenko Dmitry Anatoleviсh , Borovik Vitaly Vitalievich , Proсenko Oksana Vladimirovna , Borovik Anastasiya Vitalievna
Published: July 2021

The article attempts to present conceptually the definitions of the terms a “problem situation” and a “problem”. The problem, goal, strategy, means and conditions are analyzed in time, in interconnection and interdependence. A scheme for the solution of a problem based on the digital strategy model is presented. The one-to-one correspondence of the elements of the sets within the implementation of the corresponding measures connected with the solution of the problem is analyzed as an illustration of the way out of the problem situation. The model is analyzed which shows the time sections of the Minkowski space for the control vector, taking into account the reaction of the control vector to the influence of external and internal factors in time within the production system. The conclusion is made about the evolutionary reaction of the system to the emergence of a problem situation, which is formed for its self-preservation, prevention of system integrity violation and the possibility of automating the process of problem solution on the basis of a digital model.
Organizational and economic aspects of innovation management in agro-industrial enterprises
Authors: Anichin Vladislav , Chugay Dmitry , Khudobina Galina , Yakovenko Natalia
Published: July 2021

The economic aspects of innovation activity are determined by the fact that innovations serve to achieve the economic goals of the enterprise, act as a means of competition and require the use of economic resources. When organizing innovation activities, it is important to take into account macroeconomic factors and intra-company conditions. The authors identify three large-scale macroeconomic factors that have a significant impact on the chain of interrelated innovations in the activities of modern Russian agro-industrial enterprises. At present, the factor of creating institutions of the digital economy is beginning to take effect, in connection with which the third wave of organizational, technological and marketing innovations and the next growth of agro-industrial production in Russia are expected. Due to the different rates of economic concentration in the three areas of the agro-industrial complex, historically, unfair vertical competition has been and remains one of the limitations for innovation at agro-industrial enterprises. In the digital economy, information about the essential conditions of concluded transactions becomes available to antimonopoly authorities in real time, which allows them to quickly develop and apply regulatory actions in cases of violations of antimonopoly legislation or in cases of “failures” of the market. It is also possible to create institutions that support fair competition in the vertical and horizontal dimensions. The opportunities that open up actualize the improvement of the conditions for innovation activity at the intra-company level.
Ecological innovations for regional sustainable development: an empirical study
Authors: Kurganov Maksim , Tretiakova Elena
Published: July 2021

The article is devoted to the study of sustainable regional development from the perspective of the value-driven approach and the assessment of the environmental innovations impact on the sustainability of the regional development. The methodological framework included the sustainable development concept, the main provisions of the regional economy, the rational use of natural resources principles and the value-driven management. The study determined the level of realization of the values and interests of the population, the business community and authorities in the economic, environmental and social spheres. It has been established that achieving sustainable development goals at the regional level requires reducing the environmental intensity of enterprises, reducing the volume of pollution of the atmosphere and water resources, as well as the volume of generated production and consumption waste. The regional environmental innovations implementation is considered the main driver of positive changes in the field of natural resource management and environmental protection. Using econometric modeling, an assessment was made of the impact of environmental innovations and factors of the regional environment on the level of realization of the sustainable development values in the context of key stakeholders of the territories and the degree of coordination of their interests, as well as on key indicators of the economic activity. The environmental innovations importance in the regional sustainable development is mathematically proved and the environmental innovations specificity in the context of improving regional policy is characterized.
Possibility of implementing a cluster based on the territorial public self-government that includes sports, retailers and consumer services
Authors: Simdiankin Arkadii , Khludnev Egor , Probin Pavel , Yamalutdinov Alexey
Published: July 2021

The economic crisis has had a negative impact on the clustering processes. Nevertheless, in the current conditions there is a prospect of changing the very ideology of cluster models. It is very likely that the high impact of the volatility factor in the business environment will determine a qualitatively new format for the implementation of cluster initiatives. In most cases, the population of a particular territory is not directly involved in the process of creating a cluster but is considered as a labour force capable of achieving the goals of clustering. However, it is impossible to say that cluster projects cannot be initiated on the principle of “bottom-up development” where the population performs are not only the functions of “personnel” but also determines the feasibility of forming a project. This ensures open an equal access to the resources of absolutely all cluster participants and the population acts as an initiator, coordinator, investor and source of labour resources. In this regard, we think that it is appropriate and possible to consider the prospect of creating cluster (and similar ones) projects by the example of territorial public self-governments.
Management of the investment and construction project cost under conditions of risk and uncertainty
Authors: Bobrova Nadezhda , Ivanov Andrey , Kamenskikh Denis , Plyusnina Lyubov
Published: July 2021

The solution to the problem of managing the cost of an investment and construction project under conditions of risk and uncertainty is presented in the issue. The external and internal factors of project risks are analyzed. The concept of uncertainty is characterized as a property of the external and internal environment of the project, which underlies the occurrence of risks. Additional prerequisites for the emergence of risks, both objective and subjective, are considered. An authors’ model for managing the cost of an investment and construction project based on a process approach has been developed based on the above mentioned prerequisites. The content of the stages of the project cost management model has been determined. The possibility of managing the cost of the project through the analysis of budget spending has been investigated. In the course of the study, a comparison was made between the work schedule in accordance with the basic project plan and the actual work schedule with deviations from the project plan. Unfavorable deviations of the baseline indicators of the project were revealed, both in terms of work execution time and in the cost of work performed. It has been proved that the adverse impact of risk factors on the overall performance of the project, expressed by indicators of investment efficiency, is reduced as a result of the application of the process model for managing the cost of an investment and construction project.
Banking front-line personnel assessment by fuzzy logic approaches
Authors: Koretskiy Vladimir , Degtiareva-Galiakhmetova Marina , Kostitsyn Evgeniy
Published: July 2021

The article is dedicated to the qualitative assessment of banking personnel and the interpretation of the results with a developed fuzzy logic expert system. The authors proposed to evaluate human resources based on the Company Loyalty, Customer Service Quality and Intra-Corporate Communication which are linguistic terms for personnel to be assessed. To interpret the results of the received staff assessment, a fuzzy expert system was developed which enables the Business Efficiency of Personnel to be estimated. The expert system was tested at the front-line office of the regional bank. Regression and correlation analysis revealed high correlations between the Business Efficiency of Personnel and the quantitative results of employees. The practical relevance of the research is conditioned by the growing need to assess credit managers during the trial period or at the introduction of new products, while quantitative indicators are absent. The methods used for research comprise survey, ranking of the factors and factor analysis.
Analytical grouping of accounting for wages in health care institutions
Authors: Golova Elena , Baranova Irina , Gapon Marina
Published: July 2021

An important factor in the uninterrupted work of healthcare is a modern and decent salary for medical personnel. This issue has become especially acute in coronavirus infection when all the problems that have accumulated in the field of healthcare have become especially urgent. There was a situation of a shortage of medical personnel and the need for round-the-clock work, which led to the issue of incentive and compensation payments. In this regard, accounting is one of the innovative links that ensure uninterrupted payments to employees of medical institutions. All facts of the economic activity of the institution must be documented. However, the existing set of documentation is not always able to ensure the prompt provision of information on payroll and incentive payments, even in the context of accounting automation. The article contains research of the workflow organization in terms of remuneration on the example of one of the medical institutions in the Omsk region. The study revealed the need to improve the accounting area as one of the ways of innovative development. The article proposes a new analytical accounting register, which allows presenting information on charges to medical personnel in the context of personnel categories and comparing analytical and synthetic accounting data in terms of the amounts of accrued wages. It is proposed to integrate the proposed document into the Sail Budget 7 program, the Payroll module, which will make the calculation process more convenient, less labor-intensive, and will allow the data transfer process to be carried out automatically.
Modern approaches to Agile transformation of Russian financial and technological companies
Authors: Vorontsov Denis
Published: July 2021

The article considers the relevance of the Russian organizations Agile transformation operating in the financial technology industry. The current concepts of Agile-transformation are presented. The experience of implementing Agile transformations in large Russian banks is presented. The current processes occurring during the transformation of fintech companies are presented. The conditions and features of Agile transformation depending on the scale of a fintech company are considered. Changes in the corporate culture are analyzed from the point of view of project teams and the Agile companies as a whole. Approaches to the transformation of the company’s organizational structure are presented, with the identification and description of new implemented structural elements and roles. The change in the project methodology of a Fintech company during Agile transformation is presented as a transition, implementation and adaptation of popular Agile frameworks and hybrid project approaches based on the project methodologies of Waterfall, Scrum and SAFe. The current and practical stages of Agile transformation of large fintech companies operating in the banking market are analyzed and described in detail. Assumptions are made about the potential problems caused by the escalating competition, restrictions and consequences caused by the Covid-19 pandemic. Medium-term challenges and prospects for the transition of companies to Agile in the Russian fintech market are presented.
Citizen involvement in urban planning process in Russia
Authors: Tselishcheva Elena , Kondyukova Elena , Pobedin Aleksandr , Babanova Faina
Published: July 2021

The paper examines citizen involvement in the urban planning process. Although different forms of public control have been established in Russian legislation application of western approaches for urban planning process, organizations face low interest from local communities, on the one hand, and inability of local authorities to work with public initiative, on the other. The research is based on the multidisciplinary approach. The methodology includes deliberative democracy, advocacy planning conceptions, spatial economic theory, and urban studies. Methods of system, institutional, comparative analysis, focus groups and content analysis are used. The research has been conducted based on the materials of public space renovation projects in some major cities - regional capitals in Russia. The empirical base of the research includes acts regulating the urban planning sphere, mass media content about urban space renovation projects, materials from focus groups with representatives from local authorities and initiative citizen groups. The paper represent results of the international scientific research project “Legitimacy, urban planning and sustainability in Russia and Sweden (LUPSRUSS)” which was funded by the Swedish International Centre for Local Democracy (ICLD).
The role of higher education institutions in the development of intellectual capital
Authors: Akopov Grigory , Tiratsuyan Vazgen , Kurysheva Yulia
Published: July 2021

This article deals with the questions of intellectual capital, summarizes the results of content analysis of the notion “intellectual capital”, its essential characteristics and basic elements. Authors show the role of higher education system in generating and developing of intellectual capital of future professionals. A high level of intellectual capital is a key element of organization competitiveness and productivity and can be seen as a basis for a leading position in a particular industry. The study focuses on the development of intellectual capital of civil aviation professionals. It summarizes the results of analysis of Rostov branch of Moscow State Technical University of Civil Aviation’s experience in the field of intellectual capital development during the education of future civil aviation engineers.
Fundamentals of effective activity of structural divisions of the company
Authors: Kukartsev Vladislav , Kernitskii Valerii , Semenova Evgeniya , Kuimova Olga , Khramkov Vladimir
Published: July 2021

This article is devoted to the theoretical study of the foundations of the effective operation of the company’s structural divisions. It examines the general directions of development of companies and the main strategies that are most relevant for companies that produce goods in modern market conditions. Also, in this article, attention is paid to specific areas of improvement of divisions in companies, the main of which are precisely the production departments. To understand the essence of unit improvement, leadership strategies were considered. Methods and factors influencing the improvement of the activity of a subdivision of a manufacturing enterprise are analyzed. All factors are considered in the context of the enterprise from two sides, both external and internal, and diagrams are built for them for visual presentation. On the basis of these factors, directions were developed to increase the economic efficiency of activities. The final stage was considered 8 ways to improve the efficiency of enterprise management. At the end of the work, conclusions were drawn about the reasons that necessitate the improvement of units in the modern market. The purpose of this work is to study the main directions for the development of companies and the activities of their structural divisions.
Specific features of the relationship between creativity and inhibitory control in young adolescents
Authors: Nikolaeva Elena Ivanovna , Belyaeva Evgenia Mikhailovna
Published: July 2021

Inhibitory control develops rather late in ontogenesis since it depends on the development of the prefrontal cortex. There are contradictory data on its relationship with creativity at different stages of ontogenesis. One of the most unstudied age periods is early adolescence. It is considered an age when a child has not yet mastered the subtleties of speech expression. The purpose of the study was to reveal the connections between creativity and inhibitory control in young adolescents. Creativity is assessed with two tests: J. Gilford’s test and E.P. Torrance’s test. The go/go and go/no-go paradigms are used to assess inhibitory control. In the first case, subjects are presented with stimuli with a fractally organized structure. A reaction was required for each stimulus. The second case requires not responding to one of the stimuli to which one had previously developed a response. Each series consists of two identical parts. Data processing is carried out using SPSS software. The study sample consists of 158 students in grades 6-7 of which 61 are boys and 97 are girls. The result of regression analysis shows that none of the parameters of J. Guilford’s test are related to the parameters of inhibitory control. We attribute this to the fact that the test is verbal and adolescents find it difficult to find original solutions in the lexical domain. Overall score and flexibility (according to E.P. Torrance’s test) are related to the efficiency of inhibitory processes in the second part of the go/no-go test and to the quality of grasping the fractal structure of the sensory signal flow.
Emotional intelligence as a psychological resource and the features of its development in intellectually gifted school students
Authors: Larionova Liudmila I. , Petrov Vyacheslav , Smirnova Polina V. , Zverev Oleg M. , Karaivanova Maria
Published: July 2021

The article touches upon the relevant problems of modern psychological and pedagogical science: support for and development of gifted school students, psychological resources of personality, and emotional intelligence. At present, the problem of the features of emotional intelligence development in gifted students is theoretically and empirically underexplored within the framework of the resource approach. The goal of the study is to research the features of the development of emotional intelligence as a psychological resource in gifted adolescent school students. The following methods were used: emotional intelligence questionnaire, resilience test, D. Raven’s Progressive Matrix Scale; methods of mathematical statistics (analysis of variation, correlation analysis, etc.). The first part of the article presents an overview of studies on the problem of psychological resources and emotional intelligence, the current state of research in these fields is outlined, and the understudies issues and prospects for further studies are indicated. The empirical part presents the study results, the analysis of which reveals the specific features of emotional intelligence development in gifted adolescents compared to regular students. The obtained data indicate certain problems associated with the underdevelopment of emotional intelligence and its components in gifted adolescents which calls for further research and consideration in practical work with gifted students. The provided results of correlation analysis demonstrate a statistically significant association between the indicators of emotional intelligence and resilience. The obtained results point to the need for further study of the specifics of emotional intelligence and the opportunities for its development in gifted and non-gifted school students.
The relationship between general and emotional intelligence in preschool children
Authors: Izmaylova Elnara I. , Kuzmishina Tatyana L. , Gorelkina Maria Aleksandrovna , Korneva Elena N. , Lukinova Anastasiia Vladimirovna
Published: July 2021

This paper examines the relationship between general intelligence and emotional intelligence in preschool children older than five years and the main areas of research on general and emotional intelligence. Currently, a high level of general and emotional intelligence is viewed as a condition for achieving success both in one’s profession and in life in general. The relevance of this study is conditioned by the need to study general intelligence and emotional intelligence to improve the intellectual and emotional life of people, which in turn contributes to the solution of both individual and social problems. This study aims to review the levels of general and emotional intelligence formation in preschool children older than five years. The paper contains a retrospective analysis of the problem of studying emotional and general intelligence in Russian and foreign psychology. Various approaches to the study of general and emotional intelligence are analyzed. Based on a review of the literature on the topic of the study, the prerequisites for the emergence of the concept of emotional intelligence are outlined. The content of such concepts as “intelligence” and “emotional intelligence” is outlined, with a brief excursion into the history of the emergence and spread of these concepts. The paper also contains terms analogous to the concept of emotional intelligence and describes in detail the structural components of emotional intelligence within the framework of various models. Empirically, the levels of general and emotional intelligence of preschool children older than five years have been identified. A comparative correlation study of the levels of emotional and general intelligence of preschool children was carried out. The authors present the results of an experimental study on the absence of interdependence of general and emotional intelligence in preschool children older than five years.