bluuebunny/crossref_metadata_2025 huggingface dataset:
La representación cinematográfica de la mucama latinoamericana: La ciénaga (Lucrecia Martel, 2001) y Roma (Alfonso Cuarón, 2018)
Authors:   niversidad Complutense de Madrid, Vázquez Rodríguez Lucía Gloria , Zurian Francisco A ,   Universidad Complutense de Madrid
Published: January 2022

Dentro del cine latinoamericano cada vez encontramos más filmes que representan la naturaleza invisibilizada, neocolonialista y sexista de uno de los fenómenos más extendidos en el continente: la existencia de servicio doméstico entre las familias blancas de clase alta. Con un enfoque cualitativo que integra como categorías de análisis las características del lenguaje fílmico háptico definido por Laura Marks (2002) y la imagen-tiempo propia del cine lento (Deleuze, 1987) se argumenta la emergencia de un nuevo género cinematográfico en Latinoamérica que sitúa a la figura de la mucama en el centro formal, emocional y narrativo de los filmes (Shaw, 2017), y que cada vez atrae más interés desde los estudios fílmicos. En este sentido, se analizarán dos visiones complementarias pero opuestas de la relación entre el servicio doméstico y las familias latinoamericanas de clase alta: La ciénaga (Martel, 2001), que sitúa a la mucama Isabel (Andrea López) en los márgenes del texto fílmico, ofreciendo una visión crítica de la naturaleza explotadora del servicio doméstico; y Roma (Cuarón, 2018), cuyo enfoque nostálgico sitúa a Cleo (Yalitza Aparicio) en el centro de la narración sin pretender en ningún momento hablar en lugar de su subjetividad subalterna.
Doenças diagnosticadas pelo Laboratório de Patologia Veterinária em 2018
Authors: Felicetti Perosa Fernanda , Gris Anderson , Cechin Renan Augusto , Mingotti Taisson Rafael , Carneiro Christofe , Silva Isabela Gimenes , Bavaresco Lucas Henrique , Ascoli Baldi Kelen Regina , Milagres Augusto Gomes Teane , Mendes Ricardo Evandro
Published: January 2022

Este trabalho apresenta a casuística de diagnósticos no ano de 2018 do Laboratório de Patologia Veterinária do IFC Campus Concórdia. Foram 185 diagnósticos em bovinos, 18 em ovinos e 40 em suínos, totalizando 243. Destes, 191 (81,9%) foram através de necropsias e 44 (18,1%) através de amostras formolizadas enviadas por veterinários. Em bovinos as doenças mais incidentes foram miosite clostridial com 9 casos (5,0%); intoxicação por Prunus (sphaerocarpa) myrtifolia com 9 casos (5,0%); intoxicação por nitrato/nitrito com 7 casos (3,9%); e carcinoma de células escamosas com 7 casos (3,9%). Já em ovinos, foi hemoncose com 7 casos (38,9%) e, em suínos, a circovirose com 6 casos (15,0%).
Technology Focus: Water Management (December 2021)
Authors: Swartwout Rosa
Published: January 2022

As the oil and gas industry evolves to become more socially responsible with using natural resources such as water, economics constraints are an ever-present concern. The three highlighted papers share different approaches regarding how produced water could be managed economically. The topics span from working collaboratively between governmental agencies, industry, and academia toward practical solutions; applying digital technology; and water management for smaller operators.

The lessons learned from a regulatory perspective in Trinidad and Tobago about gaps and deficiencies in regulatory enforcements are not unique and are applicable in many parts of the world. Lessons learned include using an integrated management approach; understanding relevant environmental standards; and standardizing how solutions are evaluated and assessed, all of which could lead to better outcomes.

The digital space can be capitalized to enable cost savings in water management. Advancements such as using machine learning to optimize membrane performance in sulfate removal units is one of many possible applications.

The traditional mindset has been that economically viable produced-water management required large-scale development. The technical paper on this topic illustrates water management executed at smaller scale, such as a five-well section development plan in an unconventional reservoir that proves financially beneficial. This was accomplished by taking an integrated approach to embedding recycling and reuse of produced water in the lifecycle of the well.

As an industry, we have opportunities to manage and reduce our impact on water resources by adopting digital technology, consistent and relevant government regulations, and integrating planning throughout the lifecycle—from project inception to product delivery to end users.
Machine-Learning Techniques Track, Monitor Offshore Water-Treatment KPIs
Authors: Carpenter Chris
Published: January 2022

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 206173, “Offshore Water-Treatment KPIs Using Machine-Learning Techniques,” by Lauren Flores, Martin Morles, and Cheng Chen, Chevron, prepared for the 2021 SPE Annual Technical Conference and Exhibition, Dubai, 21–23 September. The paper has not been peer reviewed.

New water treatment facilities in the Gulf of Mexico include a seawater sulfate removal unit (SRU) to mitigate reservoir souring and scaling. Current industrial practice relies on only pressure drop and regular cleaning intervals to perform SRU maintenance, which may result in reduced membrane life because of cleaning frequency or severe membrane fouling without the capability to predict fouling based on process conditions. The machine-learning techniques applied in the complete paper aim to deliver a prediction model based on both simulation and real-time field data. The model tracks and monitors system key performance indicators (KPIs).

KPI Model Establishment

Before KPI models were established in this study, key model input and output parameters were identified. The input parameters were values that could be measured directly, including feed temperature, feed and permeate total dissolved solids (TDS), and feed and reject pressures. The output parameters were predicted membrane pressures, fouling factors, and permeate sulfate concentrations. For membrane fouling monitoring, current industrial practice over-looks the effect of other parameters on pressure drop, which may lead to incorrect decisions. In this study, fouling factor was used to reflect an accurate picture of membrane fouling.

Fouling factor is a projection of mem-brane fouling over time, typically with a value between 0 to 1. A fouling factor of 1 indicates that the aged membrane has the same fouling profile as new membrane, while a smaller fouling factor means more-severe fouling. With regard to the SRU process, the major fouling mechanisms causing flux reduction include particle plugging and biofouling.

The first step was to obtain SRU data for the prediction model. Because the SRU has not been installed, a membrane-simulation tool was applied to generate performance data under various operating conditions.

The next step was to use simulation data for model selection, training, and validation. Several models were evaluated using training data, and the model scores were compared. Metrics were used to determine the model that best fit the data used; however, extensive validation and sensitivity analyses were used to understand the model capability of generalization.

Definitions provided in this synopsis are taken from sources documented in the complete paper.
An IoT Enabled Heart Disease Monitoring System Using Grey Wolf Optimization and Deep Belief Network
Authors: S Sandhiya , U Palani
Published: January 2022

Heart disease is a deadly disease today irrespective of age group among people because they are not aware about their heart disease level, and the kind of heart diseases. It is necessary to aware about their type of heart diseases and the regular disease monitoring process in this quick world. This paper proposes a new heart disease monitoring system with the incorporation of Internet of Things and Deep Learning technique for safeguarding the patients. Here, a new feature selection algorithm which is incorporated for performing better classification through deep learning algorithm. In this proposed heart disease monitoring system, we monitor the disease level according to the inputs that are given to the IoT devices. Moreover, it classifies the patient details according to the heart disease types and the severity of the disease. Finally, it gives alarm/message to the patients according to the type of heart disease with the available inputs. The experiments have been demonstrated and proved as the proposed system is better in terms of prediction accuracy.
The Usefulness of MRI R2* Value In Diagnosing And Staging of Rat Liver Fibrosis
Authors: Yu Jin Hong , Yang Chao Feng , Zuo Hui , Das Sushant Kumar , Li Yang
Published: January 2022

Background: Liver fibrosis involves the increase of iron deposition. however, whether R2* measurement can be used as a noninvasive method to characterize processes of fibrogenesis with iron deposition is not clear. This study aims at assessing the usefulness of magnetic resonance imaging (MRI) R2* value in diagnosing and staging of rat liver fibrosis. Methods: Male Sprague-Dawley rats were injected intraperitoneally with a mixture of 1.0 ml/kg carbon tetrachloride (CCl4) and oil (1:1 v/v) twice a week for 12 weeks. Liver R2* value was quantitatively determined by multi - echo fast gradient echo sequence. Liver iron content (LIC) was evaluated by an atomic absorption spectrophotometer. The stage of liver fibrosis was assessed by pathological METAVIR scores. The performances of R2* values for each fibrosis stage were evaluated. The receiver operating characteristic (ROC) curve analysis was used to determine the optimal cutoff values for fibrosis stage. Results: R2* values and LIC gradually increased during the progression of the liver fibrosis, the correlation between the R2* values and the LIC was high-positive. There were significant differences in R2* values among the stages of liver fibrosis (F= 30.84，P < 0.001). There was a significant positive correlation between R2* values and LIC (r= 0.984, P < 0.001). The most discriminating cutoff values of R2* were 46.84 Hz for ≥ F1, 55.30 Hz for ≥ F2, 68.06 Hz for ≥ F3, and 78.79 Hz for F4. Conclusion: R2* values can be used for detecting and staging liver fibrosis. The degree of liver fibrosis was related to the degree of increase in R2* measurements.
Predicting the Surgical Site Infections in Patients Undergoing Lumbar Internal Fixation Surgery: A New Predictive Nomogram is Evelopmenting and Assessmenting
Authors: Chen Tianyou , Liu Chong , Zhang Zide , Liang Tuo , Chen Jiarui , Jiang Jie , Li Hao , Guo Hao , chen wuhua , ye zhen , yao yuanlin , liao shian , zhan xinli
Published: January 2022

Purpose
The purpose of this research is to develop and validate a nomogram of the risk of surgical site infections in Patients Undergoing lumbar Internal Fixation Surgery.
Patients and methods:
We had collected a total of 1327 patients with lumbar internal fixation surgery, 1273 patients were normal lumbar fixation group and 54 patients in the surgical site infections group. Patients are divided into two echelons of testing and verification, and R software is used as the only statistical analysis. In the training tests, first, single factor logistic regression analysis was used to select potential predictors with significant p-values. Then multivariate logistic regression analysis is used to filter out the predictors which we need. A nomogram was constructed using the coefficients of variable provided by Multivariate logistic regression analysis, the calibration and clinical applicability of the predictive model are evaluated by using the C index, calibration curve, and decision curve. In addition, we use internal verification tests to verify the built model.
Results
This unprecedented nomogram of SSI risk for lumbar Internal Fixation Surgery includes modic status, glucose, Hb, ESR, blood transfusion, sebum thickness. The model shows a good degree of discrimination, with a C index of 0.975 (95% confidence interval: 0. 964, 0. 987) and good alignment. The decision curve analysis showed that the SSI nomogram is clinically meaningful when the 1% probability threshold of the normal group is used to determine the intervention. The C-index of the validation test was 0.981(95% confidence interval: 0. 957, 1.005).
Conclusion
This novel SSI prediction nomogram combines Modic status, glucose, Hb, ESR, blood transfusion, sebum thickness, and can be easily used for individualized SSI probability prediction in lumbar Internal Fixation Surgery patients.
Anomalous Method of Cement-Sand Ratio Evaluation in Hardened Cement-Mortar or Cement-Concrete
Authors: Tiwari Shaleeni , Aggarwal Deeksha , Nirvan Arpit , Kumar Surendra
Published: January 2022

Construction or creation is a genetic human tendency and places, pyramids, houses, villas, bridges, fly-overs, etc. are living examples of this inborn tendency. Civil construction is possible through proper binding materials which can bind all the construction components together. Lime has been used for centuries for this purpose but in the modern era, Portland cement has taken its place. Portland cement is widely being used to bind bricks, stones, or other construction materials in the form of cement- mortar or cement concrete. Cement-mortar or cement -concrete is made by mixing cement in a certain ratio to fine aggregates(sand) or fine and coarse aggregates together, and this certain ratio is quite important for the durability, strength, and sustainability of any civil construction. Sometimes, civil construction gets collapsed unfortunately and the ratio of cement-sand becomes the crucial point of investigation to ascertain the cause of failure. The most used method for this purpose is the acid digestion method, which is based on an insoluble percentage of silica in the cement-mortar or cement-concrete, but this method is quite lengthy having multiple stages of filtering, drying, weighing, causing multiple sources of errors. For precision, the silica percentage is being calculated through EDX/XRF nowadays. EDX/XRF method is fast as well as precise also but requires quite a costly set up as well as quite a time consuming also in respect of proper sampling and sample preparation. The present method is almost emerged as precise as the acid digestion method but gives quicker results with fewer error sources.
Intuitionistic Fuzzy Decision Support Based on EDAS and Grey Relational Degree for Historic Bridges Reconstruction Priority
Authors: Rogulj Katarina , Pamuković Jelena Kilić , Antucheviciene Jurgita , Zavadskas Edmundas Kazimieras
Published: January 2022

Bridge management includes all actions in the life cycle of bridge, in order to insure its safety, stability and functionality. Numerous problems have been identified that are primarily related to the organization of planning and the role of decision-making in reconstruction planning of the historic pedestrian bridges. The planning process of reconstruction of these bridges is crucial due to increased traffic load, poor condition or damage of bridges. Some of these bridges are part of the cultural heritage, while some are unfairly neglected. The motivation for this research arose from the need to establish the priority for the reconstruction of historic pedestrian bridges to achieve their safety, stability, functionality, and cultural preservation. A new decision support model based on intuitionistic fuzzy group decision-making to the multicriteria analysis of the historic pedestrian bridges reconstruction planning is created. The model combines multicriteria method Evaluation Based on Distance from Average Solution and grey relational degree (GRD) with intuitionistic fuzzy theory. Three relevant decision groups of experts are formed, with the knowledge and expertise in the area of research problematic, establishing criteria for the evaluation. A new approach of consistency of criteria weights is proposed. The intuitionistic fuzzy likelihood function is developed for the aggregation of evaluations of bridges. Furthermore, GRD values are calculated to determine the reconstruction priority ranking of bridges for each decision group. The final ranking is defined by integrating Integer Linear Programming (ILP) and Ant Colony Optimization (ACO), determining spatial-functional, time, and financial constraints.
Common Variable Immunodeficiency and Its Inflammatory Neurological Manifestations: A Case Report and Literature Review
Authors: Martins Bárbara , Miranda Joana , Pinto Maria João , Costa Andreia , Silva-Pinto André , Melo Natália , Ceia Filipa , Costa José Torres , Guimarães Joana
Published: January 2022

Purpose
Common variable immunodeficiency disorders (CVID) are a group of primary immunodeficiencies characterized by impaired immunoglobulin production and dysregulated immune response. Neurological manifestations have been described in few patients, and little is known about its clinic and therapeutic approach. Thus, the aim of this work was to review the literature on it and to help differentiate CVID from its mimics, especially sarcoidosis.
Methods
We described a case report and included a literature review of inflammatory neurological involvement in CVID.
Results
A 32-year-old female patient with a medical history of recurrent bacterial infections, temporal focal epilepsy and granulomatous lung disease under study, and cervix squamous cell carcinoma, was initially admitted to the emergency department due to intracranial hypertension. After excluding infectious and neoplastic etiologies, the most likely hypothesis was that granulomatous pulmonary, cerebral, and leptomeningeal inflammatory involvement were associated with sarcoidosis. Two years later, a diagnosis of CVID was made, and the patient was secondarily diagnosed with Granulomatous and Lymphocytic Interstitial Lung Disease (GLILD) and related inflammatory brain disease – both complications of CVID. After starting targeted treatment with immunoglobulin replacement and pulse glucocorticoids followed by a chronic taper, the patient became stable. However, three consecutive failures in immunoglobulin intake led to disease recurrence with relapse of neurological manifestations.
Conclusion
This case illustrates the complex multiple organ manifestations of CVID. When granulomatous conditions arise in these patients, GLILD with multisystem involvement should be taken in consideration. Early treatment with combined steroids and immunotherapy seems to be effective in controlling CVID’s neurological manifestations.
Spatial patterns and climate drivers of malaria in three border areas of Brazil, Venezuela and Guyana, 2016-2018
Authors: Wangdi Kinley , Wetzler Erica , Cox Horace , Marchesini Paola , Villegas Leopoldo , Canavati Sara
Published: January 2022

Introduction

In 2020, 77% of malaria cases in the Americas were concentrated in Venezuela, Brazil, and Colombia. These countries are characterized by a heterogeneous malaria landscape and malaria hotspots. Furthermore, the political unrest in Venezuela has led to significant cross-border population movement. Hence, the aim of this study was to describe spatial patterns and identify significant climatic drivers of malaria transmission along the Venezuela-Brazil-Guyana border, focusing on Bolivar state, Venezuela and Roraima state, Brazil.
Methods

Malaria case data, stratified by species from 2016-2018, were obtained from the Brazilian Malaria Epidemiology Surveillance Information System, the Guyana Vector Borne Diseases Program, the Venezuelan Ministry of Health, and civil society organizations. Spatial autocorrelation in malaria incidence was explored using Getis-Ord (Gi*) statistics. A Poisson regression model was developed with a conditional autoregressive prior structure and posterior parameters were estimated using the Bayesian Markov chain Monte Carlo simulation with Gibbs sampling. Climatic covariates were precipitation and minimum and maximum temperature.
Results

There were 685,498 malaria cases during the study period. Plasmodium vivax was the predominant species (71.7%, 490,861). Malaria hotspots were located in eight municipalities along the Venezuela and Guyana international borders with Brazil. Plasmodium falciparum decreased by 1.6% (95% credible interval [CrI] 1.5%, 2.3%) and 9.6% (95% CrI 1.5%, 25.2%) per 1 cm increase in six-month lagged precipitation and each 1°C increase of minimum temperature without lag. Each 1°C increase of one-month lagged maximum temperature increased P. falciparum by 6.6% (95% CrI 4.8%, 21.7%). P. vivax cases decreased by 1.0% (95% CrI 1.0%, 1.1%) and 7.0% (95% CrI 6.5%, 7.5%) for each 1 cm increase of precipitation lagged at six-months and 1°C increase in minimum temperature lagged at six-months. There was no significant residual spatial clustering after accounting for climatic covariates.
Conclusion

Malaria hotspots were located along the Venezuela and Guyana international border with Roraima state, Brazil. In addition to population movement, climatic variables are important drivers of malaria transmission in these areas.
Trichoderma Asperellum as a Novel Source to Prepare Chitosan Oligosaccharides by Enzymatic Hydrolysis and Its Antimicrobial Activity
Authors: Siqiang Wang , Jinyu Zhang , Lichao Pan , Kun Li , Liuya Wang , zhu zhenyuan
Published: January 2022

Chitosan oligosaccharides (COS), as an important biological functional component, are mainly produced from marine resources, while their source face great challenges, such as seasonal variation, discontinuity and demineralization. In this study, the chitosan was extracted by alkaline method from Trichoderma asperellum, and then it was degraded with enzymatic hydrolysis to obtain the COS. The physicochemical characterization of chitosan from Trichoderma asperellum was compared with commercial chitosan, including chitosan content, deacetylation degree, chemical group, and molecular weight. Then, the enzymatic hydrolysis rates of Trichoderma asperellum chitosan and commercial chitosan were similar, 89.37 and 91.56%, respectively. Moreover, the composition of COS was tested by TLC, HPLC and MALDI-TOF, which results shown that Trichoderma asperellum COS was composed of chitotriose, chitopentaose and chitohexaose, and commercial COS was composed of chitotriose, chitotetraose, chitopentaose, chitohexaose and four acetylated chitohexaose. The antibacterial activity for Trichoderma asperellum COS was greatly stronger commercial COS. In conclusion, Trichoderma asperellum proved to be a novel potential source for COS production.
Multi-factor Models after the Financial Crisis - An empirical analysis for the German stock market
Authors: Hennecke Peter , Jessen Ragnar , Topalov Mihail
Published: January 2022

The subject of this paper is the analysis of multi-factor models at the German stock market, based on the latest stock market data. The focal point is the question in how far the Capital Asset Pricing Model-compatible single-factor model, the three-factor model developed by Fama and French, as well as Carhart’s four-factor model can serve as empirical explanatory contributions after the financial crisis of 2007 and 2008. The collected findings suggest that even after the crisis, Carhart’s model will continue to have strong empirical explanatory power for the cross section of German stock returns in the evaluation period. Moreover, it becomes apparent that the requirements of an equilibrium model might still be met.
Effect of short-term educational intervention on complementary feeding index among infants in rural Bangladesh: a randomized control trial
Authors: Rahman Aminur , Bhuiyan Badrul , Das Sumon Kumar
Published: January 2022

Background: Timely, adequate and appropriate CF is essential for the growth and cognitive development of infants, but until today, evidence-based information is scarce in terms of impact evaluation of CF index (CFI). The study aimed to examine the effect of the short-term intervention of promoting CFCF practices on the nutritional status of infants in rural Bangladesh. Methods: An educational-intervention study followed a randomized controlled trial (RCT) design (NCT03024710). Mothers and family members in the intervention arm received intensive counselling on CFCF through community health workers (CHWs), whereas existing healthcare services were received in the comparison arm. The study was carried out in the rural Matlab sub-district of Bangladesh between April 2011 and March 2013. In the specified study areas among 360 mother-infant pairs systematically assigned into intervention group and comparison group. Short-term educational intervention on CF was provided for the intervention group and existing services were un-intervened for the comparison group. The outcome of interventions was evaluated after the implementation period using Generalized equation estimation model. Results: At baseline, the study participants were not different except mean height, weight-for-age Z score (WAZ) and religion in between two groups. The mean CFI was significantly higher at intervention area than the comparison and higher category of CFI (score 10 or more) was significantly higher at intervention area than comparison. After adjustment, one-unit CFI increased height-for-age z score by 0.07 units and decreased WAZ by 0.13 units in the intervention group but not significantly changed observed at comparison group. Conclusion: Guided short-term nutritional intervention and developed CFI indicated a significantly better score in intervention area than comparison groups and would be a well adaptable tool for future studies. Trial registration: The trial was registered (NCT03024710) at clinical trial registration website. Date of registration: 1/19/2017Name of the registry: Clinical Trial.govDate of registration: 19/1/2017 (retrospective registered)URL of trial:https://clinicaltrials.gov/ct2/show/NCT03024710
New Strain of Bjerkandera Adust as a Potential Biocontrol Agent Against Wheat Scab
Authors: Li Suping , Li Yong , Feng Xiao , Zhang Jingjie , He Xinhua
Published: January 2022

Bjerkandera adusta can decompose polycyclic aromatic hydrocarbons including cellulose and lignin, but its roles in inhibiting plant pathogens are unknown. Here, the confrontation culture and greenhouse pot experiments were employed to study the control effect of B. adusta M1 on Fusarium graminearum and wheat scab. The results indicted the B. adusta M1 fermentation broth (FB) could inhibit the growth of F. graminearum and decrease the disease index of wheat scab, and the control effects on wheat scab were 93.27% of the chemical fungicide carbendazim. The growth rate was significantly (P < 0.05) higher in B. adusta M1 than in F. graminearum, indicating a strong competitiveness by B. adusta M1. The images from the scanning electron microscope showed substantial deformations of the hyphae of F. graminearum penetrated by the hyphae of B. adusta M1, indicating a strong mycoparasitism by B. adusta M1. Similarly, FB increased the activities of leaf catalase, peroxidase and phenylalanine ammonia-lyase related to disease resistance, and decreased the cell membrane permeability and malondialdehyde. So we concluded that B. adusta M1 could be a promising fungal strain to control the detriment of F. graminearum to field cereal productions.
Regulatory Emotional Self-efficacy and Psychological Distress among Medical Students:Multiple Mediating Roles of Interpersonal Adaptation and Self-acceptance
Authors: Zhang Xuemin , Yue Heng , Sun Junfang , Liu Min , Li Cuiyun , Bao Hugejiletu
Published: January 2022

Background

Psychological distress (depression, anxiety and stress) is more common among medical students than in the general population, and is an important cause of insomnia, internet addiction, substance abuse, decreased academic performance and increased suicidality in medical students.
Methods

To examine the mechanism by which regulatory emotional self-efficacy affects medical students' psychological distress, a questionnaire of 539 medical students using an interpersonal adaptability scale, regulatory emotional self-efficacy scale, self-acceptance scale and depression-anxiety-stress scale was conducted.
Results

① Regulatory emotional self-efficacy, interpersonal adaptability and self-acceptance are significantly positively correlated, but they are significantly negatively correlated with psychological distress. ② The mediation model shows that interpersonal adaptation and self-acceptance are the mediation variables of the effect of regulatory emotional self-efficacy on psychological distress, and the total mediation effect value is -0.37, accounting for 86.05% of the total effect (-0.43). Specifically, the effect involves three paths: first, the indirect effect of regulatory emotional self-efficacy → interpersonal adaptation → psychological distress (effect value-0.24); second, the indirect effect of regulatory emotional self-efficacy → interpersonal adaptation → self-acceptance → psychological distress (effect value-0.08); and third, the indirect effect of regulatory emotional self-efficacy → self-acceptance → psychological distress (effect value -0.05).
Conclusions

Interpersonal adaptation and self-acceptance have a significant mediating effect between regulatory emotional self-efficacy and psychological distress, and the chain mediating effect of interpersonal adaptation and self-acceptance is also significant.
Identification of a 12-LncRNA long Lymph Node Metastasis Prognostic Signature for Cervical Cancer
Authors: Cheng Jingxin , Chen Rui , Liu Qin , Luo Yuehua , Zhang Xiaohua , Gao Jinli
Published: January 2022

Background: Despite advances in treatment strategies, the prognosis in early-stage patients with lymph node metastasis (LNM) remains poor, and the 5-year overall survival is ~30%. Therefore, in this study, we aimed to explore the LNM-related long noncoding RNAs (lncRNAs) for the prognosis of cervical cancer patients. We obtained LNM-relevant mRNA and lncRNA expression profiles, copy number variant (CNV), and clinical follow-up data of patients with early-stage cervical cancer from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases.Results: Patients in the training set were divided into a high-risk score group with shorter overall survival (OS) or a low-risk score group with longer OS (p < 0.001); similar results were also determined for the validation set (p < 0.001). In addition, the CNV including chromosome arms 2q, 11q and 18q deletion, 11, 19q and 17q amplification were the most common forms in the high-risk score group. PF4708671 and GW4417556 might be sensitive drugs in chemotherapy, and the programmed death-ligand 1 expression of the low-risk score group was higher than that of the high-risk score group.Conclusions: The prognostic model based on LNM-relevant lncRNAs could help determining the immune status of cervical cancer patients at an early stage; this is conducive to accurate clinical diagnosis and individual treatment.
Double and Triple Burdens of Malnutrition Among Child-Mother Pairs in Ethiopia: Spatial and Survey Regression Analysis
Authors: Tarekegn Bethelihem Tigabu , Assimamaw Nega Tezera , Atalell Kendalem Asmare , Kassa Selam Fisiha , Muhye Addis Bilal , Techane Masresha Asmare , Alemu Tewodros Getaneh , Wubneh Chalachew Adugna , Belay Getaneh Mulualem , Tamir Tadesse Tarik , Kassie Destaye Guadie , Wondim Amare , Terefe Bewuketu , Ali Mohammed Seid , Fentie Beletech , Gonete Almaz Tefera , Tekeba Berhan , Desta Bogale Kassahun , Dessie Melkamu Tilahun , Ayele Amare Demsie
Published: January 2022

Background

Evidences on double and triple burdens of malnutrition at household level among child-mother pairs is a key towards addressing the problem of malnutrition. In Ethiopia, studies on the double and triple burdens of malnutrition are scarce. Even though, there is a study on the double burden of malnutrition at national level in Ethiopia it has limitations. It doesn’t assess the triple burdens at all and a few forms of the double burden of malnutrition among child-mother pairs. Therefore, this study aimed to determine the prevalence and associated factors of double burden and triple burden of malnutrition among child-mother pairs in Ethiopia.
Methods

A total sample of 7,624 child-mother pairs from the Ethiopian Demographic and Health Survey 2016 were included in the study. All analysis were performed considering complex sampling design. Anthropometric measurements and hemoglobin levels of children and anthropometric measurements of their mothers were considered primarily to compute double burden of malnutrition (DBM) and triple burden of malnutrition (TBM). Spatial analysis was applied to detect geographic variation of prevalence of double and triple burdens of malnutrition among EDHS clusters. Bivariable and multivariable binary survey logistic regression models were used to assess the factors associated with DBM and TBM.
Results

The overall weighted prevalence of DBM and TBM respectively were 1.8% (95%CI: 1.38-2.24) and 1.2% (95%CI: 0.83-1.57) among pairs of a child-mother in Ethiopia. Significant clusters of high prevalence of DBM and TBM were identified. In the adjusted multivariable survey logistic regression models, middle household economic status [AOR=0.23, 95%CI: 0.06, 0.89] as compared to the poor, average birth weight [AOR=0.26, 95%CI: 0.09, 0.80] as compared to large birth weight and children aged 24-35 months [AOR=0.19, 95%CI: 0.04,0.95] as compared to 6-12 months were less likely to experience DBM. Average birth weight [AOR=0.26, 95%CI: 0.09, 0.80] as compared to large birth weight and children aged 24-35 months [AOR=0.19, 95%CI: 0.04,0.95] as compared to 6-12 months were less likely to experience TBM.
Conclusion

There is low prevalence of DBM and TBM among child-mother pairs in Ethiopia. However, interventions tailored on geographic areas, wealth index, birth weight and child birth could help to control the emerging DBM and TBM at household level among child-mother pairs in Ethiopia.
Clearing the water? The impact of the Central Environmental Protection Inspection on water quality
Authors: Liu Minhui , Yuan Qianqian , Yang Feng
Published: January 2022

This study examined whether China’s Central Environmental Protection Inspection (CEPI), an innovative environmental regulation, has successfully reduced water pollution. We compiled a new water pollution data file and found that the third round of inspection significantly reduced the concentrations of ammoniacal nitrogen (NH3-H) and chemical oxygen demand using potassium permanganate as an oxidizing agent (CODMn) (indicators often mentioned in government reports). However, no improvements were found in DO concentrations (not mentioned in reports). This suggests that a more comprehensive water quality indicator system or standard should be provided in advance to better guide water quality improvement. Additionally, based on the characteristics of the CEPI, this research explored water pollution externalities. We found that the inspection mitigates water pollution externalities across jurisdictional boundaries when it is judged by NH3-N concentrations.
Multi-stakeholder Validation of Entrustable Professional Activities in Family Medicine
Authors: Francois Jose , Clendenning Ben , Fisk Derek , Buchel Tamara
Published: January 2022

Background:The development of Entrustable Professional Activities (EPAs) has generally focused on expert panel approaches, which are often limited to physician stakeholders. Optimally, a much wider group of stakeholders should be consulted and include all people gaining value from trainees’ patient care performance. The present study explored the perceptions of a variety of stakeholder groups regarding the relevance and comprehensiveness of EPAs developed for a Canadian Family Medicine Residency program.Methods: Through the use of an online survey consisting of dichotomous and open-ended questions, this study explored and compared the perceptions of a variety of stakeholder groups (policy makers, health administrators, health professionals, teachers, and public) regarding the relevance and comprehensiveness of 25 EPAs articulated by a family medicine residency program.Results:Agreement on appropriateness of the 25 articulated EPAs ranged from 90% to 100%, displaying a high level of alignment between stakeholders. Stakeholders identify two gap areas within the EPA framework: 1) provision of surgical assistance and 2) addictions care.Conventional content analysis identified three key themes that cut across multiple areas of the survey: 1) Interprofessional collaboration (IPC), 2) Inclusivity, and 3) Scope of EPAs. Comparative analysis consisted of exploring agreements, gaps, and other differences of perspectives between stakeholder groups. Although many of the stakeholder groups made comments regarding IPC and Inclusivity, the patient group in particular was more likely to raise these themes. Comments from patient groups were also overall more general, identifying overarching trends rather than specific pinpoint issues. Physicians, other health professionals, and resident groups, (Ie. health professional groups) on the other hand tended to answer with much more specificity, identifying issues relating to scope of EPAs.Conclusions: The present study demonstrates that a multi-stakeholder approach can feasibly be used to validate an EPA framework. In addition to confirming that a previously articulated set of EPAs largely reflected the range of activities expected of family physicians serving a population, it identified a number of potential areas of improvement in the framework.
Establishing Level-Area-Volume Relationships of Darawat Reservoir Using Time Series Remote-Sensing Images
Authors: Hameed Fahad , Qureshi Muhammad Ateeq , Khalil Rao Muhammad Zahid
Published: January 2022

The study aims to determine the level-area-volume relationship for the newly constructed Darawat reservoir on non-perennial channels located in the Kirthar National park in Jamshoro district of Sindh, Pakistan. Landsat-8, Digital Elevation Model (DEM), Modified Normalized Difference Water Index (MNDWI), and In-situ data, were used. A set of equations represented the relationship between three parameters (Level-area-volume) derived from five different models (exponential, linear, logarithmic, polynomial, and power). Results showed a significant relationship in Level-area-volume. The coefficient of determination showed relationships for water level-surface area range from 0.941 to 0.991, for water level-volume a range reflected from 0.943 to 0.998, and for area-volume represented a range from 0.928 to 0.994. The study estimated results validated by the percentage difference (PD), the root means square error (RMSE), and coefficient of determination (R2) using surface areas of the year 2019 and in-situ water levels. Power model relatively showed the best results, PD=0.227, RMSE=0.335, and R2= 0.982. The study suggests the remote sensing techniques may utilize, if pre-constructed bathymetry data is available, to estimate level-area-volume relationships for rainwater resources management, flood control, and environmental monitoring.
Combining the Multivariate Statistics and Dual Stable Isotopes Methods for Nitrogen Source Identification in Coastal Rivers of Hangzhou Bay, China
Authors: Zhou Jia , Hu Minpeng , Liu Mei , Yuan Julin , Ni Meng , Zhou Zhiming , Chen Dingjiang
Published: January 2022

Coastal rivers contributed the majority of anthropogenic nitrogen (N) loads to coastal waters, often resulting in eutrophication and hypoxia zones. Accurate N source identification is critical for optimizing coastal river N pollution control strategies. Based on a 2-year seasonal record of dual stable isotopes (δ15N-NO– 3 and δ18O-NO– 3) and water quality parameters, this study combined the dual nitrate (NO– 3) stable isotope method and the absolute principal component score-multiple linear regression (APCS-MLR) model to elucidate N dynamics and sources in two coastal rivers of Hangzhou Bay. Water quality/trophic level indices indicated light-to-moderate eutrophication status for the studied rivers. Spatio-temporal variability of water quality was associated with seasonal agricultural, aquaculture and domestic activities, as well as the seasonal precipitation pattern. The APCS-MLR model identified soil + domestic wastewater (69.5%) and aquaculture tailwater (22.2%) as the major nitrogen pollution sources. Further, the dual stable isotope method identified soil N, aquaculture tailwater, domestic wastewater and atmospheric deposition N contributions of 35.3 ±21.1%, 29.7 ±17.2%, 27.9 ±14.5%, and 7.2 ±11.4% to riverine NO– 3 in the Cao’e River (CER) and 34.4 ±21.3%, 29.5 ±17.2%, 27.4 ±14.7%, and 8.7 ±12.8% in the Jiantang River (JTR), respectively. The APCS-MLR model and dual stable isotope method showed consistent results for riverine N source identification. Combining these two methods for riverine N source identifications effectively distinguished the mix-source components from the APCS-MLR method and alleviated the high cost of stable isotope analysis, thereby providing reliable N source apportionment results with low requirements for water quality sampling and isotope analysis costs. Moreover, this study highlights the importance of soil N management and aquaculture tailwater treatment in coastal river N pollution control.
Prevalence of Anxiety, Depression, and Post-Traumatic Stress Disorder Among Amputees Attending Jaipur Foot Trust Artificial Limb Centre in Kenya
Authors: Mohamed Illham , Mutavi Teresia , Gitau Catherine
Published: January 2022

Background: Amputees have been noted to present with various psychiatric disorders including anxiety, body image disturbances, depression, and Post-Traumatic Stress Disorder (PTSD). However, there is limited data available on the prevalence of anxiety, depression, and PTSD among amputees in Kenya despite the high incidences of amputations in Kenyan hospitals. This study aimed at finding out the prevalence of anxiety, depression, and post-traumatic stress disorder among amputees attending the Jaipur Foot Trust Center in Kenya.Method: This study took a cross-sectional descriptive study design. One hundred and forty-one patients attending the Jaipur Foot Trust were recruited to participate in the study after giving informed consent using a non-probability purposive sampling method. A socio-demographic questionnaire was used to collect socio-demographic characteristics. The Patient Health Questionnaire (PHQ-9) was used to assess the patient's depression. The Generalized Anxiety Disorder (GAD-7) scale was used to assess the patient's anxiety level and The Impact of Event Scale (IES-R) was used to assess the severity of post-traumatic stress disorder (PTSD). Data analysis was done using Statistical Package for Social Science (SPSS) version 23. Results: Findings from this study showed high rates of psychiatric morbidity where two-thirds of the patients reported PTSD (65%) with more than three-quarters of patients being diagnosed with depression (89.4%) and anxiety (91.5%). Also, there was a significant correlation between depression, anxiety, and PTSD, such that participants who had higher scores on anxiety and depression had significantly higher PTSD scores.Conclusion: Anxiety, Depression, and PTSD are very common psychological reactions in patients who have undergone amputation. The researchers expected that some of the sociodemographic factors and some amputation-related characteristics would have a relation with psychiatric comorbidity. However, the findings of this study did not show any such relationship except the relation between anxiety, depression, and PTSD. Early psychological assessment and interventions after amputations will help alleviate psychological distress
An evaluation of the efficacy of percutaneous screw fixation without bone grafting in Sanders Type-II and Type-III displaced intra-articular calcaneal fractures
Authors: Luo Gang , Fan Chongyin , Gao Peili , Huang Wei , Ni Weidong
Published: January 2022

Background: The aim of this retrospective monocentric study was to investigate the clinical efficacy of percutaneous screw fixation without bone grafting in Sanders Type II and Type III displaced intra-articular calcaneal fractures (DIACFs).Methods: This retrospective case–control study analysed 38 patients with type Sanders Type-II and Type-III DIACFs admitted from January 2018 to January 2020, including 30 males and 8 females aged 21 to 61 years [(42.6±9.6) years]. According to the Essex-Lopresti classification, 27 of the fractures were the tongue type, and 11 were the joint compression type. According to the Sanders classification, 27 of the fractures were type II, and 11 were type III. All patients were treated with percutaneous screw fixation, and no patients received bone grafting. The radiologic parameters evaluated included the BÖhler angle, Gissane angle and height of the calcaneum. In addition, the American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot scores, Maryland Foot Score (MFS), and visual analog scale (VAS) score were determined.Results: All patients were followed up for 18-42 months [(25.2±9.5) months]. All fractures healed, and immediately postoperatively, the calcaneal height had recovered to 39.8±2.1 mm, the BÖhler angle had recovered from 4.2°±13.6° preoperatively to 27.2°±3.4° (P=0.000) immediately postoperatively, and the Gissane angle had recovered from 103.3°±9.7° preoperatively to 129.6°±5.1° (P =0.000). No differences were found in the outcome measures six-months postoperatively (BÖhler angle, p=0.24; Gissane angle, p=0.77; calcaneal height, p=0.82) or at final follow-up (BÖhler angle, p=0.33; Gissane angle, p=0.69; calcaneal height, p=0.28) compared to the immediately postoperative values. At the final follow-up, the AOFAS score was 91.7±7.4 points, with an excellent and good rate of 92.1%; the MFS was 90.3±7.8 points, with an excellent and good rate of 92.1%; and the VAS score was 2.2±1.5 points. None of the patients had incision complications, and one patient developed traumatic arthritis.Conclusion: Percutaneous screw fixation without bone grafting in Sanders Type-II and Type-III DIACFs can achieve good recovery and maintenance of the BÖhler angle, Gissane angle and calcaneum height. Moreover, it has the advantage of a low complication rate.
Cyanobacterial diversity through culture-dependent and independent approaches in Chapada das Mesas National Park, Maranhão, Brazil
Authors: Butarelli Ana Carolina de Araújo , Ferreira Lucas Salomão de Sousa , Riyuzo Raquel , Dall'Agnol Hivana Melo Barbosa , Piroupo Carlos Morais , Silva Aline Maria da , Setubal João Carlos , DallAgnol Leonardo Teixeira
Published: January 2022

The Chapada das Mesas National Park (CMNP) is a Conservation Unit in brazilian Cerrado biome, which is considered a hotspot for biodiversity conservation and possess important rivers, waterfalls and springs with economical and touristic importance. This study objective was to characterize the total and microbial photosynthetic community of the CMNP from surface sediment samples from waterfalls of two touristic sites: Pedra Caída and Farinha river. These samples were cultivated in selective medium for photosynthesizers and both the raw samples and the enriched ones were submitted to DNA extraction and sequencing of the V3-V4 hypervariable region of the 16S rRNA gene on the Ion Torrent platform. The reads were analyzed using QIIME2 software and the Phyloseq package. The enrichment allowed detecting and identifying many genera of cyanobacteria in the Chapada das Mesas National Park, which would probably not be possible without the combination of approaches. A total of 34 genera of photosynthetic microorganisms were classified in the samples from the consortia, highlighting “Chloroplast” (45.60%) and Synechocystis_CCALA_700 (10.10%) as the most abundant groups in the tropical alkaline lakes of Maranhão. As for the functional analysis, metabolic functions associated with methanotrophy and methylotrophy, hydrocarbon degradation, phototrophy and nitrogen fixation were predicted. The results highlight a great diversity of photosynthetic microorganisms in Cerrado and the importance of using a combination of approaches when analyzing target groups who usually are underrepresented like photosynthetizers.