bluuebunny/crossref_metadata_2025 huggingface dataset:
A criança com Transtorno do Espectro Autista, a escola e o professor: algumas reflexões
Authors: Matias Hélen Bandeira Rosso , Probst Melissa
Published: October 2018

O presente estudo propõe uma reflexão sobre o transtorno do espectro autista (TEA), a criança, a escola e a ação e importância da ação docente. Objetivou-se, entre outros aspectos, refletir sobre os processos educativos e particularidades das crianças com Transtorno do Espectro Autista. Para a realização do estudo, do qual o presente texto é resultante, optou-se pela pesquisa qualitativa, de revisão bibliográfica. Partindo do pressuposto de que o Transtorno do Espectro Autista (TEA) ainda é um tanto quanto desconhecido, no contexto social e educacional, justifica-se a discussão da questão. Conclui-se que conhecer a criança e o seu mundo particular pode tornar esse processo inclusivo, de aceitação como um processo duradouro, que poderá servir de amparo à criança, ao professor e à família, lembrando que o acesso à escola é um direito de todos.
A formação musical na educação infantil: a questão docente e as possibilidades da musicalização
Authors: Kastein Valéria Regina Botaro , Pacífico Marsiel
Published: October 2018

A musicalização é um componente fundamental para a Educação Infantil, estando contemplada no Referencial Curricular Nacional para a Educação Infantil, visto que propicia o desenvolvimento da criança em seus aspectos cognitivos, afetivos, estéticos e sensoriais. Neste artigo, por meio de uma revisão de literatura da área como Rosa (1990), Girard (2004) e Brito (2003), demonstramos o evidente distanciamento do ideal formativo caro à música e as práticas pedagógicas dos profissionais da Educação Infantil. Apesar dos avanços históricos em relação à Educação Infantil, ainda encontramos uma grande defasagem nas práticas de musicalização nas escolas, o que pode ser compreendido como resultante de um conjunto de fatores, no qual, sobretudo, destacamos a falta da formação adequada, seja na formação inicial ou na continuada dos professores da Educação Infantil. Por fim, apontaremos alguns princípios que podem fundamentar uma prática musical mais rica, potencializadora do desenvolvimento da criança.
Poetry
Authors: Richards Neil
Published: October 2018

Paris in Chagall
By Neil Richards

Bloh-Da-weth
By Neil Richards
Online Education as a New Practice of Humanism
Authors: Sylkina Svitlana
Published: October 2018

The current stage of the human progress is characterized by the high dynamism and global changes in all aspects of human life. The societies currently pass through a deep process of transformations that requires a new understanding of the human phenomenon and revision of humanism, new social practices, and forms of education. Higher school needs to achieve a very important goal. It is to create contemporary education paradigm, which would be based on shift from one paradigm centered on the University and teacher professional knowledge to a new one, which will be centered on the students and their needs in education. In this article, online education is observed as one of the ways of a new realization of humanism in educational practice. The author also analyzes the humanistic potential of Massive Open Online Courses (MOOC), its advantages and disadvantages as far as examined the prospects of online education. In conclusion the author mentions that online education due to its main characteristics (openness, accessibility, freedom of choice) is based on human rights and the principles of equality and could be identified as a new practice of humanism.
The Extended Ecological Approach: Networks of Life, Cognition, Action and Communication
Authors: Knyazeva Elena
Published: October 2018

The possibility and prospects of use of an extended ecological approach in scientific research and in various areas of practice is substantiated in the article. It is shown that ecology can be considered not only in terms of co-existence and co-evolution of man and nature, but also as ecology of mind, knowledge, action, communication and management. Such kind of extended ecological approach has a strong interdisciplinary basis and demonstrates the methodological power of interdisciplinarity in modern science. The ecological approach becomes a tool for the study of specific properties and character of links installed in the networks of life and cognition, action, and managerial activities, including the educationalimpact of teachers on students.
Efficacy of Analgesic Therapy after Hip and Knee Arthroplasty
Authors: Markov P. V. , Pal’Shin G. A. , Komissarov A. N.
Published: October 2018

Efficacy of pain syndrome drug therapy using aceclofenac in combination with tolperisone after total knee and hip arthroplasty was studied. Study included 100 patients. Patients from group 1 ( n =30) received ketorolac, from group 2 (n=35) - aceclofenac, from group 3 (n=35) - aceclofenac in combination with tolperisone, for 3 postoperative days in recommended doses. Severity of pain syndrome by VAS, range of motion, and dynamics of soft tissue edema was assessed. It was shown that combined therapy with aceclofenac and tolperisone was more effective in pain syndrome reduction, contributed to more marked regress of soft tissue edema and more complete restoration of movements as compared to monotherapy with nonsteroid anti- inflammatory drugs.
Arthroplasty Using Autologous Multipotent Mesenchymal Cells and Collagen Membrane Chondro-Gide
Authors: Bryanskiy A. I. , Kulyaba T. A. , Kornilov N. N. , Rumakin V. P. , Gornostaev V. S.
Published: October 2018

Surgical treatment results for 13 patients with local deep defects of the articular surface of femoral condyle are presented. Surgical treatment was performed in two steps. At first step diagnostic arthroscopy with removal of loose intraarticular bodies, resection of injured menisci and harvesting of fat body tissues for multipotent mesenchymal stromal cells (MMSC) isolation were applied. Second step consisted of knee arthroplasty; zone of defect was covered with collagen membrane Chondro-Gide under which MMSC were implanted. Control arthroscopy with biopsy of articular surface fragment in the zone of defect restoration was performed to four patients (30.8%) 2 years after arthroplasty. It is shown that after surgical intervention cartilage regeneration goes on owing to fibrillar cartilage formation. In 2 years follow up good results were achieved in 92.3% of cases that proved the efficacy of the elaborated technique for restoration of knee joint function and slowing down of degenerative-dystrophic changes development
Method to Analyze the Complications in Traumatology and Orthopaedics Based on the Form of Recording the Conformity of Fragment Biomechanical Characteristics with Fixator Arrangement
Authors: Kesyan G. A. , Av Zhadin , Av Tsiskarishvili , Kuz’Menkov K. A.
Published: October 2018

The most common mistake resulting in the development of pseudarthrosis and suppuration is inadequate choice of metal construction that prevents from performing biochemically substantiated osteosynthesis. A form for recording the conformity of bone fragment biomechanical characteristics with fixator arrangement that enables to plan surgical intervention as well as to perform retrospective analysis of osteosynthesis quality regardless of the type of chosen metal construction.
Low Invasive Achilles Tendon Suture in Outpatient Surgery Using Achillon System
Authors: Samkov A. S. , Zeinalov V. T. , Panov D. E. , Koryshkov N. A. , Ivanov K. S. , Khodjiev A. S. , Sobolev K. A.
Published: October 2018

Experience in treatment of 10 patients with Achilles tendon subcutaneous traumatic rupture is presented. All patients were men aged from 30 to 54 years. Remoteness of injury was under 10 days. All operations were performed using Achillon system. Follow up period made up from 6 months to 2 years. In 9 patients complete restoration of tendon function with good excursion in the suture zone was confirmed by US examination. In 1 patient failed suture in 8 weeks after surgery required an open tendon suturing. Achillon system combines all possibilities of open suture and advantages of low invasive technique and can be recommended to application in outpatient practice.
Vascularized Bone Autoplasty with Graft from Medial Femoral Epicondyle in Scaphoid Pseudarthrosis
Authors: Golubev I. O. , Yulov R. V. , Bushuev O. M. , Merkulov M. V. , Kutepov I. A. , Maksimov A. A. , Grishin V. M.
Published: October 2018

Nineteen patients (16 - 49 years) with scaphoid pseudarthrosis were treated using vascularized bone autograft from medial femoral epicondyle. Mean term since scaphoid fracture made up 30.5 ± 21.2 months. In all cases avascular necrosis of the proximal fragment, scaphoid humpbach deformity and dorsal intercalated segment instability (DISI) were present. In 16 (84.2%) consolidation in the zone of scaphoid pseudarthrosis was achieved at terms from 8 to 12 weeks after operation. In 3 (15.8%) unsatisfactory results were observed. Average scapholunate angle correction made up 13°. Average force of feast and pinch grasps increased on the average by 2.5 and 1.5 times, respectively. One year after surgery the average estimation by DASH scale decreased by 9.6 points at average, from 27 to 13.4 points.
Clinical Study of the Influence of Implants Made of Different Metals on the Physical Status of Experimental Animals
Authors: Gatina E. B. , Akhtyamov I. F. , Shakirova F. V. , Manirambona Zh. K.
Published: October 2018

Biocompatibility of implants made of steel 12X18H9T, steel 12X18H9T coated with titanium and hafnium nitrides, and steel 12X18H9T coated with titanium and zirconium nitrides was studied in rats. Implants that represented pins 8-10 mm long and 0.5 mm in diameter were inserted intramedullary into the middle third of the tibia after drilling. The ends of pins were turned down and placed under the skin. The wound was sutured tightly. Dynamics of body weight and temperature as well as the condition of the hair, eyes, oral and nasal mucosa were assessed on days 10, 30, 60 and 90 after implantation. It was shown that implants coated with titanium and hafnium nitrides caused minimum systemic and local reactions while implantation of pins coated with titanium and zirconium nitrides resulted in the development of more pronounced inflammatory changes on both the local and systemic level.
Method for Glenoid Bone Defect Plasty in Recurrent Shoulder Instability
Authors: Prokhorenko V. M. , Fomenko S. M. , Filipenko P. V.
Published: October 2018

Technique for glenoid bone defect plasty in posttraumatic shoulder instability using the porous titanium nickelide (Ti-Ni) graft is presented. This method is an alternative to Latarjet operation and autoplasty with the graft from the iliac crest. The shape and size of the graft was determined by MSCT data and the graft was sawed out from cylindrical billets with diameter of about 2.5 cm and wall thickness - 1 cm. Two screw holes were drilled and the graft was placed into the defect. That technique was applied in 6 patients with long lasting history of recurrent anterior instability and instability relapses after shoulder stabilization using other surgical techniques. Preoperative shoulder functional state by Rowe scale averaged 35.0 points versus 93.3 points after operation. One year follow up showed no cases of instability relapse. The advantages of this technique are the possibility of accurate glenoid anatomic shape reconstruction, absence of graft resorption and reduction of intervention duration.
Tribochemical Component of Oxidative Stress Development at Artificial Joints Implantation. Part 5. Pro-oxidative Properties and Interrelation of Titanium and Non-Metallic Orthopaedic Material Wear Particles with Antioxidants
Authors: Bulgakov V. G. , Tatarinov V. F. , Gavryushenko N. S.
Published: October 2018

Radical-forming ability of artificial wear particles of BT6 titanium alloy and nonmetallic materials was studied using modelling reaction of cumene oxidation. It was stated that alloy particles initiate formation of radicals and consecutive repeated cumene oxidation by metallic particles took place with significantly higher rate of radicals’ formation. Particles of nonmetallic materials (polyethylene, corundum ceramics, carbon nanocomposite) are inert and do not possess radical-forming ability that ensures their advantage in prevention of possible development of adverse free radical reactions in surrounding implant tissues.
Potentialities of Minimally Invasive Osteosynthesis in Treatment of Malleolus Fractures
Authors: Solod E. I. , Lazarev A. F. , Ermolaev E. G.
Published: October 2018

Treatment results for 71 patients with malleolus fractures are presented. In 32 patients (comparative group) surgery was performed by AO/ASIF technique after edema resolution. Thirty nine patients from the main group were operated on by our minimally invasive technique using V-shaped pins and threaded pins on the next day after admission independently on the presence of edema in the ankle joint region. All patients were operated on at terms from 1 to 3 weeks after injury. Duration of hospitalization averaged 16 and 10 days, restoration of joint function made up 6 and 2 weeks for the patients from the comparative and main group, respectively. Complications were observed only in patients from the comparative group, i.e. marginal skin necrosis in 8 (25%), inflammatory complications in 5 (15.6%), metal fixator migration in 1 (3.1%) and fracture nonunion in 4 (12.5%) patients. Outcomes were assessed by AOFAS Ankle- Hindfoot Scale. Mean point made up 90.3 in the main group and 88.6 in the comparative jnt. In the experimental part of the study the strength (tensile and shear) of 3 types of osteosynthesis for medial malleolus fracture were compared: with either 2 cannulated screws, V-shaped pin or 2 biodegradable screws of glycolized lactic acid was compared. Although the osteosynthesis of medial malleolus with V-shaped pin was the least strong it met the requirements of internal osteosynthesis.
Idiopathic Multifocal Osteolysis: Case of Surgical Treatment
Authors: Pozdeev A. P. , Zakhar’Yan E. A. , Buklaev D. S. , Krasnogorskiy I. N. , Zubairov T. F.
Published: October 2018

Idiopathic osteolysis is a rare disorder characterized by spontaneous, massive and progressive resorption of bone tissue. Massive osteolysis results from proliferation of blood and lymphatic vessels with thin walls, resembling capillaries, in the bone and surrounding soft tissues. Literature review on this problem and clinical case of a patient successfully operated on using the technique elaborated at our clinic are presented. Surgical interventions enabled to achieve the restoration of tubular bones integrity and ensured conditions for independent patient’s movement. Possibility of the performance of reconstructive surgical interventions for the restoration of limb weight bearing ability that is reasonable to combine with bisphosphonate therapy.
Biologic Characteristics of Bone Substituting Tissue Engineering Construction Based on Calcium Phosphate Ceramics, Autologous Mesenchymal Stromal Cells and Fibrin Hydrogel
Authors: Mamonov V. E. , Chemis A. G. , Komlev V. S. , Berkovskiy A. L. , Golubev E. M. , Proskurina N. V. , Sats N. V. , Drize N. I.
Published: October 2018

Biological characteristics of bone substituting tissue engineering construction (TEC) that contained porous calcium phosphate ceramic granulate (CPC) of phase structure ((tricalcium phosphate (TCP)), fibrin hydrogel and autologous multipotent mesenchymal stromal cells (auto-MMSC) induced and non-induced to osteogenic differentiation were studied in vivo. The following characteristics of TEC were determined: ability to transfer within its structure the viable auto-MMSC with preservation of their regeneration potential; ability to osteogenesis only under conditions of orthotopic implantation; ability of induced to osteogenic differentiation auto-MMSC to participate in the reparative processes for not more than within 6 weeks after implantation; negative affect of fibrin hydrogel on the osteoinductive properties of CPC within TCP structure. It was shown that to provide osteogenesis in the implanted TEC not only the viable auto-MMSC but simultaneous presence of osteoinductive and osteoconductive factors was required. No bone formation in a critical bone defect and in ectopic implantation takes place without observance of these conditions.
Morbidity of Musculoskeletal Diseases among Children and Adolescents in 2010-2014
Authors: Es’Kin N. A. , Andreeva T. M.
Published: October 2018

On the state statistical observation data the rates and dynamics morbidity of musculoskeletal diseases among children and adolescents are presented. Stabilization of musculoskeletal diseases morbidity among children and steady growth morbidity among adolescents are detected. In structure of musculoskeletal diseases among children and adolescents arthropathies of different genesis and deforming dorsopathies prevail. Overwhelming majority of patients receive outpatient treatment. The ways of specialized orthopaedic out-of-hospital care perfection are discussed.
Factors Affecting the Terms of Fracture Consolidation
Authors: Matsukatov F. A. , Gerasimov D. V.
Published: October 2018

Dependence of the consolidation of spiral tibial fracture treated with transosseous osteosynthesis upon the initial transverse fragments dislocation, patient’s age, remoteness of injury, reposition accuracy and fixation stability was analyzed. Priority factors that will allow realizing the maximum potentialities of the technique are determined.
Analysis of the Experience of Carbon Nanostructured Implants Use in Traumatology and Orthopaedics
Authors: Borzunov D. Yu. , Shevtsov V. I. , Stogov M. V. , Ovchinnikov E. N.
Published: October 2018

Analysis of the carbon nanostructured implants (CNI) safety and efficacy for the treatment of bone pathology was performed at different clinics of the Russian Federation. Devices showed their efficacy at substitution of intervertebral disc and vertebral body defects as well as at plasty of long bone defects of various etiology. The rate of effect absence did not exceed 6.1%. No serious adverse effects were recorded. It is concluded that CNI possesses the number of characteristics (osteoinduction, bioinertia, safety) that allow using it in traumatology and orthopaedics.
Peculiarities of Drainage after Total Knee Arthroplasty
Authors: Kavalerskiy G. M. , Smetanin S. M. , Chenskiy A. D. , Gritsyuk A. A. , Lychagin A. V.
Published: October 2018

Treatment results for 65 patients were analyzed depending on the approach to the knee joint drainage after arthroplasty. Active drainage was performed using two large-diameter tubes (group 1, n=16), one large-diameter tube (group 2, n=20), one small-diameter tube (group 3, n=15). In group 4 (n=14), no drainage was performed. Hemoglobin level, knee joint circumference at the level upper patellar pole, volume of drainage discharge and the number of days for exudation via contraperture after drainage tube removal (groups 1-3), pain intensity by visual analog scale, terms of wound gluing and sutures removal, frequency of hemotransfusion were assessed. Statistically significant expediency of active drainage with 1 large-diameter tube and pleats was proved. Without drainage a statistically significant lower decline in hemoglobin levels on 3rd and 5th postoperative days was observed but the terms for wound edges adhesion and the period of knee edema increased.
Clinical Economic Analysis of the Use of Enoxaparin, Rivaroxaban and Dabigatran Etexilate for Venous Thromboembolism Prophylaxis (VTP) in Patients after Vast Orthopaedic Operations
Authors: Es’Kin N. A. , Dergach E. V. , Pyadushkina E. A.
Published: October 2018

Clinical economic analysis of the use of enoxaparin, rivaroxaban and dabigatran etexilate for venous thromboembolism prophylaxis (VTP) in patients after vast orthopaedic operations within the RF public health system was performed. For cost calculation the modelling of decision tree where the presence/absence of clinically significant hemorrhages as the index of anticoagulant safety and VTP incidence as efficacy index were considered. The model was based on the meta-analysis of the published randomized studies results and indirect comparison performed using those data. Only direct medical costs were taken into account. Anticoagulant therapy costs were calculated for the drug dosing regimen according to the use instructions registered in RF. The time horizon of the model was in line with the average duration of thromboprophylaxis after orthopaedic operations: 21 day for enoxaparin and dabigatran, and 25 days for rivaroxaban. Determinate analysis of sensitivity including the evaluation of clinical and economic efficacy of drugs after either total hip or knee arthroplasty was performed. Total costs per patient made up 11 486.99 rub for enoxaparin, 9 035.07 rub for dabigatran and 6 172.63 rub for rivaroxaban use. During sensitivity analysis rivaroxaban preserved its advantage in all scenarios. Rivaroxaban is a preferable drug for VTP prophylaxis after vast orthopaedic interventions as with higher clinical efficacy it requires lower costs.
Peculiarities of Reparative Osteogenesis of Injured Thoracic and Lumbar Vertebral Bodies at Different Terms after Trauma
Authors: Bogomolova N. V. , Shul’Ga A. E. , Zaretskov V. V. , Smol’Kin A. A. , Norkin I. A.
Published: October 2018

The analysis of the results of morphologic examination of vertebral body bone tissue obtained intraoperatively from 43 patients (20 - 67 years) with thoracic and lumbar spine injuries at different terms after trauma was performed. All patients were operated on via anterior approach to create ventral fusion. In the examined serial samples of vertebral body structures the quality and regeneration potential of bone tissue were assessed. It was shown that cell differentiation during the osteogenesis process was closely associated with angiogenesis. In the zones with active growth of microcirculatory bed vessels the normal cycle of osteoblast and osteocytes took place while hypoxia and acidosis resulted in pathologic osteogenesis. In patients under 50 years, both males and females) the full value consolidation time averaged 5 months. In patients over 50 years, independently of the gender, the decrease of spongy structures volume and bone mineral density was observed. The recommendations on surgical treatment tactics of patients with thoracic and lumbar vertebral body injuries were given.
Surgical Treatment of Femoral Neck Fractures with Dynamic Derotation Оsteosynthesis
Authors: Dubrov V. E. , Yudin A. V. , Shcherbakov I. M. , Ragozin A. O. , Matveev A. L. , Zyuzin D. A. , Saprykina K. A.
Published: October 2018

Fracture of the femoral neck is a common injury of the human skeleton. High rate of postoperative complications induces to the search of optimum osteosynthesis technique. Treatment results for 259 patients (182 females, 77 males, mean age 72 years) with femoral neck fractures were analyzed. In study group (n=114) a dynamic derotation osteosyntesis and in control group (n=145) - DHS, a bundle of V-shaped curved pins, cannulated screws were used. Mathematic modelling of bone-implant system in different variants of derotation fixator screws position under load was performed. Use of dynamic derotation constructions in Garden 1 and Garden 2 femoral neck fractures ensured a consolidation of fractures in all clinical observations, in Garden 3 fractures - in 46.4%. Early dosage weight bearing not exceeding 60% of the body weight did not result in either fragments displacement or raise of the rate of femoral head avascular necrosis development. In patients under 60 years it is preferably to use dynamic derotation constructions with 4 screws placed in the femoral neck.
Influence of Inclination Angle on the Polyethylene Insert Wear in Experimental Module of Hip Endoprosthesis
Authors: Kolesnik A. I. , Gavryushenko N. S. , Bulgakov V. G. , Frolov E. B. , Fomin L. V.
Published: October 2018

Localization and the area of polyethylene insert wear in friction pair ofthe experimental module of hip joint (HJ) endoprosthesis was studied under laboratory dynamic conditions simulating its biomechanics at HJ external rotation contracture. It was stated that localization and the area of wear depended on the angle of horizontal inclination infriction pair of HJ endoprosthesis. Almost the same areas of polyethylene wear in anterior and posterior insert segments were observed when inclination angle was equal to that of the hip joint. Reduction of inclination angle resulted in the increase of wear surface in the anterior segment and its decrease in the posterior one. Displacement of the wear zone into the anterior segment was accompanied by the reduction of total insert wear area. At repeated loadings it created conditions for the higher polyethylene insert wear.
Perspectives of Arthroscopic Surgery at Treatment of Elbow Joint Diseases
Authors: Salikhov M. R. , Kuznetsov I. A. , Shulepov D. A. , Zlobin O. V.
Published: October 2018

The present review is dedicated to the problems and treatment techniques in elbow joint diseases. Basic methods of conservative and surgical treatment for osteoarthritis in the initial stages, chondromatosis, elbow osteochondritis dissecans and lateral epicondylitis are considered. Potentialities of arthroscopic interventions for the treatment of these conditions are presented and the main problems as well as the urgent aspects of arthroscopic treatment for elbow joint orthopaedic pathology at the current stage of surgery development are considered.
Draft Recommendations. Pharmacotherapy for the Prevention of Repeated Fractures in Patients with Osteoporosis after Surgical Treatment of Pathologic Proximal Femur Fracture
Authors: Mironov S. P. , Rodionova S. S. , Torgashin A. N.
Published: October 2018

Treatment of pathologic proximal femur fractures complicating the course of systemic osteoporosis is most often limited by surgical intervention as until now trauma and orthopaedic surgeons have no concrete recommendations on pharmacologic correction of metabolism disorders typical to the pathology, that aggravate in the postoperative period due to operative trauma. Proposed draft recommendations are a part of National clinical recommendations “Treatment for pathologic fractures of skeleton bones complicating the course of osteoporosis”. This issue of recommendations is only applicable to pharmacotherapy directed to the correction of bone tissue remodeling with regard for the fracture localization and volume of surgical intervention. Present recommendations are intended for the improvement of patients’ life quality, reduction of present and future losses from pathologic fracture as well as the prevention of repeated fractures.
Surgical Treatment for Severe Decompensated Neuromuscular Scoliosis in Patient with Spinal Muscular Atrophy type II
Authors: Baklanov A. N. , Shaboldin A. N. , Barchenko B. Yu.
Published: October 2018

Treatment results for 16 years old patient with grade 4 thoracolumbar scoliosis on the background of Type II spinal muscular atrophy are presented. One step surgical treatment via dorsal approach was performed: posterior corrective two-rodtranspedicular corporal screw C7 - S1 fusion with fixationof iliac bones by transpedicular system with bone autoplasty + osteomatrix. Surgical intervention resulted in the formation of satisfactory trunk balance, reduction of pelvic distortion and improvement of the patient’s quality of life.
Bacteriostatic Characteristics of Bone Substituting Constructors Obtained from Composite Materials Based on Natural Polymers, Calcium Phosphates and Vancomycin
Authors: Karalkin P. A. , Sergeeva N. S. , Komlev V. S. , Sviridova I. K. , Kirsanova V. A. , Akhmedova S. A. , Shanskiy Ya. D. , Kuvshinova E. A. , Fedotov A. Yu. , Teterina A. Yu. , Barinov S. M. , Kaprin A. D.
Published: October 2018

Introduction.The local delivery of therapeutic antibiotic concentrations to the zone of surgical intervention in bone pathology enables either to prevent or significantly decrease the rate of osteomyelitis development. It that study the efficacy of vancomycin inclusion and release from three dimensional constructors based on sodium alginate, gelatin and octacalcium phosphate and vancomycin intended for bone defect substitution was studied.

Materials and methods. Prototyping of 3D constructors was performed by extrusion 3D printing. Various concentrations of vancomycin were added as an additional component at the stage of preparation of hydrogel (“ink”) for printing. Physical testing of the constructors included electron microscopic evaluation of their microstructure and porosity as well as the study of mechanical strength for compression and stretching. Functional activity of printed constructors with respect to the test strain S. aureus ATCC 6538-P was assessed by a disc-diffusion method in vitro and on the model of infected excision skin wound in rats -in vivo.

Results. Analysis of the kinetic curves showed that the principal release of the drug in the model liquid took place within the first day. The total volume of the bound and released vancomycin made up approximately 20% of the calculated initial amount for all three concentrations. Formation of the marked growth inhibition zone of S. aureus strain in presence of vancomycin rich constructors was demonstrated in vitro. Insertion of constructors into the zone of infected skin defect resulted in a decrease of inflammatory processes severity and rate as well as accelerated the terms of complete wound healing.

Conclusion. Study results showed the principle potentiality of bone substituting implants 3D-printing using multicomponent hydrogel compositions without change of separate components characteristics.
EXPERIENCE IN USE OF BUVANESTIN AND OTHER MODERN LOCAL ANESTHETICS IN TRAUMATOLOGY AND ORTHOPAEDICS
Authors: Vasil’kov V. G. , Marinchev V. N. , Emelina N. G. , Tryashkina T. I. , Shilov A. Yu. , Polich A. S.
Published: October 2018

Clinical experience in use of Buvanestin and other local anesthetics (Marcaine,Naropin) in traumatology and orthopaedics is presented. Careful evaluation of the effect of various drugs (Refortan, Ringer’s solution, Mafusol) preinfusion upon the status of hemodynamics in elderly and senile patients at operations for femoral fractures has been performed. It has been shown that by the anesthetic properties Buvanestin practically does not differ from Marcaine. Preinfusion of Mafusol has shown the advantages over the Ringer’s solution and Refortan in ensuring more stable hemodynamics during operation and in the early (within 20-30 min) postoperative period.
EPIDEMIOLOGY OF PROXIMAL FEMUR IN THE REPUBLIC OF BELARUS’
Authors: Romanov G. N. , Chernyanin I. Yu. , Rudenko E. V. , Lesnyak O. M. , Zakroeva A. G.
Published: October 2018

Purpose: to determine the incidence of proximal femur (PF) fracture in the inhabitants of the Republic of Belarus aged 50 years and over. The study was initiated by the Russian Association on Osteoporosis with support from International Osteoporosis Foundation. Material and methods. The data collection is performed by the protocol that assumes an active search of PF fracture cases for 3 years in all available sources with their subsequent verification within one city of the Republic of Belarus with population over 100 000 residents. Results. Standardized indices of PF fracture incidence in the Republic of Belarus for males and females aged 50 years and over made up 147 and 250 cases per 100 000 inhabitants, respectively. The obtained data are in line with the general information on PF fracture incidence in the neighboring countries. According to the population growth forecast the 25.8% increase of PF fracture cases in this age group is expected by 2050.
LATE DIAGNOSIS OF MUCOPOLYSACCHARIDOSIS TYPE IV (MAROTEAUX–LAMY SYNDROME)
Authors: Mikhailova L. K. , Polyakova O. A. , Zakharova E. Yu. , Voskoboeva E. Yu. , Kuleshov A. A. , Vetrile M. S. , Lisyanskiy I. N.
Published: October 2018

Peculiarities of the clinical manifestation of mucopolysaccharidosis type IV diagnosed at the age of 30 years only are presented. In spite of favorable disease course after the age of 30 years combined vertebral canal stenosis more marked at C0-C1 level, cervical myelopathy and spastic tetraparesis that required surgical intervention. Special attention was paid to the genetic aspects of diagnosis and potential causes of delayed disease development.
ANATOMIC AND PHYSIOLOGICAL FEATURES OF FACET JOINTS. EVOLUTION OF FACET FIXATION FOR THE TREATMENT OF PATIENTS WITH LUMBAR SPINE DEGENERATIVE DISEASES
Authors: Byval’tsev V. A. , Kalinin A. A. , Okoneshnikova A. K. , Pestryakov Yu. Ya.
Published: October 2018

The literature review presents the anatomical features of facet joint structure and their pathologic changes in lumbar spine degenerative diseases as well as the steps of development and modern methods of facet fixation, their technical peculiarities and results of application.
DEPENDENCE OF THE OUTCOMES OF ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION ON THE TUNNEL POSITIONING
Authors: Bantser S. A. , Tikhilov R. M. , Trachuk A. P. , Bogopol’skiy O. E. , Rybin A. V. , Shulepov D. A. , Salikhov M. R.
Published: October 2018

Purpose of study: based on the analysis of clinical and radiation data to determine the most favorable positioning of the bone tunnels at different techniques of anterior cruciate ligament (ACL) reconstruction.

Study design: retrospective analysis.

Patients and methods. Face-to-face and a remote examination was performed in 202 patients at terms from 1.5 to 5 years after primary ACL autoplasty using the graft from the popliteal muscle tendons. All patients were divided into 3 groups depending on the technique of the bone tunnels formation. The patients from the 1stgroup (n=109) were operated on using transtibial technique, from the 2nd(n=52) and 3rd(n=41) groups – using anteromedial technique with the positioning of the femoral tunnel in the central and anteromedial part of ACL attachment, respectively. Bone tunnels positioning was determined using CT with 3D reconstruction. Subjective evaluation was performed by IKDS-2000, KOOS and Lysholm knee score. To assess the tibiofemoral dislocation the anterior drawer, Lachman and pivot shift tests as well as arthrometry (comparison with the healthy side) were performed.

Results.In patients from group 1 the tibial tunnel was positioned in the plane of either central or posterolateral part of ACL attachment. In groups 2 and 3 the tunnel was positioned closer to the anteromedial part. In the majority of patients form group 1 the femoral tunnel was positioned in the zone or slightly forwards of the anteromedial part of ACL femoral attachment, in group 2 – in the plane of central or posterolateral part, in group 3 – in the anteromedial part. In patients from the 1st and 2nd groups the subjective evaluation by IKDS-2000, KOOS and Lysholm knee score was comparable and much higher in the 3rdgroup (p<0.05). Objective evaluation showed positive manual tests results in 47 patients (62%) from the 1st group, 19 patients (51%) – 2ndgroup and 4 patients (11%) – 3rdgroup. Arthrometry showed the increase of anteroposterior tibiofemoral dislocation by 3.4±2.6 mm in the 1st group, 3.1±2.7 mm in the 2nd group and 1.2±1.4 mm. Statistical analysis did not reveal significant difference in knee stability between the patients from the 1stand 2ndgroups.

Conclusion.Positioning of the femoral tunnel in the plane of anteromedial part of ACL attachment ensures better surgical treatment functional results. In anteromedial technique the use of posterosuperior contour of the lateral femoral condyle as a reference point enables to improve the accuracy of femoral tunnel positioning as well as to minimize the error risk at intraoperative marking.
THE SECURITY AND PRIVACY PROBLEMS OF AUGMENTED REALITY TECHNOLOGIES
Authors: Samotyy V. , Dzelendzyak U.
Published: October 2018

The analysis of security and confidential problems, connected with augmented reality systems and support technologies have been conducted. These problems have been analyzed using 2 categories: system volume and functionality. In the first category the augmented reality systems (AR-systems) of growing scale: single applications, multiple applications within a single AR platform, and multiple communicating AR-systems have been reviewed. For this category the problems connected with input, output and data access have been analyzed. Based on the described problems of information security in AR-technologies, the main directions of their solutions have been indicated.
OPTIMIZATION OF OCCUPATIONAL RISK MANAGEMENT
Authors: Bochkovskyi A.
Published: October 2018

The analysis of regulations in the field of labour safety and risks management was conducted. Several systemic methodological problems relevant to labour safety management system were identified. The main problems, complicating the realization of occupational risks management process are: uncertainty of purposes, complication of realization procedure and absence of tools for its optimization. To eliminate these problems optimal method of occupational risks management, based on mathematical models, was developed and proposed. Results of this study prove that the models should include indexes relatedto expenditures on occupational safety and also to harmful factors and their influence on an employee. The proposed models can be concidered as two optimization tasks, aiming at maximization of employee's safety together with the minimization of expenditures on occupational safety. These tasks are related to the convex programming and can be solved both with numerical methods and with the using of the standard MS Excel programme pack.
SAFETY CULTURE AS A KNOWLEDGE SYSTEM AND CONDITION OF CONSTANT DEVELOPMENT OF THE SOCIETY
Authors: Zhurbynskyi D. , Tarasenko A.
Published: October 2018

The article deals with the situation in the field of life safety, which has arisen in Ukraine under the influence of modern dynamic processes. The main problem issues, related to the decrease of the citizens' safety culture level in Ukraine together with the sharp increase in the risks of  natural, technological and socio-political emergencies, are determined. Modern education in the field of life safety aims at obtaining fundamental knowledge, skills and abilities, developing attitudes, values and human behavior. That's why security-oriented disciplines in higher educational institutions of Ukraine are extremely important and necessary components of the educational process. The ways of forming a new worldview, a system of ideals and values, in other words, an integral safety culture in the process of professional training of a future specialist are proposed in the article.
IDENTIFICATION AND DETERMINATION OF CUPRUM IN VEGETABLE RAW MATERIALS
Authors: Scherbyna O.
Published: October 2018

The ways of entering the environment and harmful effects on human health of copper compounds (copper) and products of their decomposition are considered. Among the chemicals that pollute different objects of the environment, a significant group of toxicants are metals and their compounds. Metals play an important role in the physiological processes of living organisms. However, the ingestion of large quantities of metals into the body leads to poisoning. The subject of research was copper and its compounds. In insignificant quantities it is contained in the cells of almost all human organs. The content of copper is replenished at the expense of food products, especially cereals, peas, mushrooms, meat, and others. Widespread use of copper in industry, agriculture, everyday life requires detailed research in various objects. The method of separation, purification, detection and quantitative determination of coupler compounds in biological objects (seeds of leguminous plants) is proposed. The identification was carried out by qualitative reactions, and the quantitative determination - by the photoelectrocolorimetric method on the basis of the reaction with ditison. The developed method can be determined from 2 to 10 mg of Cuprum in 100 g of the object under study. Detection limit is 0.5 mg.
ENVIRONMENTAL LOGISTICS OF WASTE MANAGEMENT IN VILLAGES, SETTLEMENTS AND PEASANT HOUSEHOLDS
Authors: Popovych N. , Malyovanyi M. , Popovych V. V.
Published: October 2018

The absence of processing plants, sorting lines or stations, special rolling stock in villages and settlements leads to accumulation of waste in open territories, burning, dumping into streams, rivers and reservoirs. Particularly acutely these ecological problems affect mountain territories, reserves and reserves of our state, where the guarantee of clean environment is in the first place. In line with the approaches to household waste management at the village, village and private peasant household level, hierarchical levels are set: satisfactory, risky, critical. Existing waste management approaches in rural areas are generally inappropriate, since a significant part of the pollutants enters the hydro, lithosphere and biogeocoenosis. The emergence of the current situation is the construction of garbage processing plants. The developed generalized logistic system of waste management in rural areas highlights the impact of garbage disposal approaches on regional ecological safety.
ANALYSIS OF EXISTING ANALOGUES FOR THE SYSTEM OF ENVIRONMENTAL MONITORING DURING OPERATIONAL ACTIVITIES
Authors: Tkachuk P.
Published: October 2018

The article analyzes existing analogues for the adaptive system of ecological monitoring during operational activities of the Frontier Service units. The analysis was done from the point of view of the functional scheme formation for assessing changes in the state of border natural and man-made geosystems using the methodology of the system approach. The problem is the maintenance of environmental security during a regional armed conflict. The purpose of the work is to carry out an analysis of possible analogues of the adaptive system of ecological monitoring. A structural and functional model of the mechanism for environmental safety regulation during emergency situations of military and technogenic nature is proposed. The novelty of the work lies in the complex application of methods, receptions, tools and instruments for environmental safety regulation.
FUTURE ECONOMISTS' LEGAL TRAINING IN THE CONTEXT OF COMPETENCY BUILDING APPROACH
Authors: Galushchak I.
Published: October 2018

The article deals with the problem of the competency building approach implementation in the system of higher education of Ukraine. Its methodological imperfection is noted, and the initial algorithm to improve the providing of such an approach is proposed. A comparative analysis of the concepts "competency" and "competence" is presented. The main components of the future economists' legal competency are investigated. The conceptual framework of competent training are analyzed and the main approaches to future economists' legal training are substantiated. The prospects of further researches in this direction are determined.
MODEL OF PEDAGOGICAL EXCELLENCE IMPROVING BY TEACHERS OF NATURAL FACILITIES IN THE PROCESS OF INTEGRATED PROFESSIONAL SELF-PERFECTION
Authors: Fedyuk G.
Published: October 2018

The concept of model and features of pedagogical modeling are considered. The constructed model of pedagogical excellence improving by teachers of natural sciences in the process of continuous professional self-perfection is substantiated. It presents its structure, the content of each block and the characteristic of the role in the process of pedagogical excellence improving by teachers of natural sciences.
RESEARCH ON DOMESTICALLY PRODUCED FIRE-FIGHTING FOAM AGENTS FOR SUBSURFACE FIRE EXTINGUISHING
Authors: Voitovych T. M. , Gusar B. M. , Kovalyshyn V. V. , Koshelenko V. V. , Grushovinchuk O. V.
Published: October 2018

This research outlines the problems of fire extinguishing in tanks, and describes a projected model of an experimental installation for the vertical tank fire simulation. The research also describes a method of extinguishing fires of oil and petroleum products in vertical steel tanks by supplying low expansion foam to the tank base directly into the fuel layer. The time of diesel fuel and gasoline fires extinguishing with the help of general and special purpose fire-fighting foam agents was calculated. Experimental investigations on definition of the fire-extinguishing efficiency of domestically producted fire-fighting foam agents by subsurface fire extinguishing of tanks were carried out.
DISTRIBUTION OF THERMAL BALANCE DURING FIRES IN CLOSED ROOMS
Authors: Gulida E. M.
Published: October 2018

The methodology of determining the thermal balance during fires in closed room was developed. Thermal balance during a fire is primarily influenced by the temperature of the seat of fire. This temperature depends on the burning rate of combustion products, the area of the fire and its duration and the mass of gas in the volume of the room. The lower calorific value also has a significant effect on the of thermal balance. The value of the heat flow, which passes into the walls of the room at all stages of the fire, was estimated. Analytic expression for determining the heat absorption coefficient depending on the duration of free burning was obtained. The results of research show that the heat absorption coefficient φ is not a constant value – during the fire it changes its value and reaches a maximum (no more than 0.5). Increasing of the volume of the room leads to increasing of the heat loss (more heat goes into the environment), which reduces the thermal load on the building structures.
MATHEMATICAL MODEL FOR DETERMINING THE STEP TIME AND DISTANCE COVERED BY THE DROPLETS OF LUQUID FIRE-FIGHTING AGENT DURING THE PROCESS OF FIRE EXTINGUISHING IN THE CLOSED ROOM
Authors: Ukhanska O. , Shtangret N.
Published: October 2018

The article deals with the mathematical model for determining the step time and distance covered by the droplet of liquid till the moment of contact with the horizontal plane. Numerical values of the step time and distance covered till the moment of contact with the horizontal plane are obtained. Experimental studies aimed on determining the effective diameter of the droplet are performed. According to effective diameter value an effective mass of the droplet is determined. After obtaining the effective mass value the step time and distance covered by the droplet of liquid till the moment of contact with the horizontal plane are calculated using a mathematical model.
FIRE PREVENTION DEVICES ON THE BASIS OF THE WASTE ZEOLITE CATALYSTS "TSEOSOR 5A"
Authors: Ferents N. , Pavliuk Yu.
Published: October 2018

The analysis of technical and operational properties of dry fire prevention devices was carried out. The properties of waste zeolite catalysts such as "Tseosor 5A" and their behavior in high temperature conditions were investigated. The efficiency of the use of waste zeolite catalyst "Tseosor 5A " as a flame retardant element of dry fire prevention devices was proved. The critical nozzle diameters of the fire prevention devices were calculated for various vapor-gas-air mixtures.