bluuebunny/crossref_metadata_2025 huggingface dataset:
Periodic Solutions and KAM Tori for the Spatial Maxwell Restricted $$N+1$$-Body Problem with Manev Potential
Authors: Ascencio Mauricio , Vidal Claudio
Published: July 2022

We consider the motion of an infinitesimal mass under the Newtonian attraction of N point masses forming a ring plus a central body where a Manev potential ($$-1/r + e/r^2$$

-
1
/
r
+
e
/

r
2

, $$e \in {\mathbb {R}}$$

e
∈
R

), is applied to the central body. More precisely, the bodies are arranged in a planar ring configuration. This configuration consists of $$N-1$$

N
-
1

primaries of equal mass m located at the vertices of a regular polygon that is rotating on its own plane about its center of mass with a constant angular velocity $$\omega $$
ω
. Another primary of mass $$m_0=\beta m$$

m
0

=
β
m

($$\beta >0$$

β
>
0

parameter) is placed at the center of the ring. Moreover, we assume that the central body may be an ellipsoid, or a radiation source, which introduces a new parameter e. The existence and stability of periodic solutions of the spatial Maxwell restricted $$N+1$$

N
+
1

-body problem is obtained using averaging theory. The determination of KAM 3-tori encasing some of the linearly stable periodic solutions is proved. The planar case is moreover considered.
The Legacy of Gildas
Authors: Joyce Stephen J.
Published: July 2022

A provocative new investigation into the shadowy figure of Gildas, his influence and representation.
Disturbance growth on a NACA0008 wing subjected to free stream turbulence
Authors: Faúndez Alarcón José M. , Morra Pierluigi , Hanifi Ardeshir , Henningson Dan S.
Published: July 2022

The stability of an incompressible boundary layer flow over a wing in the presence of free stream turbulence (FST) has been investigated by means of direct numerical simulations and compared with the linearised boundary layer equations. Four different FST conditions have been considered, which are characterised by their turbulence intensity levels and length scales. In all cases the perturbed flow develops into elongated disturbances of high and low streamwise velocity inside the boundary layer, where their spacing has been found to be strongly dependent on the scales of the incoming free stream vorticity. The breakdown of these streaks into turbulent spots from local secondary instabilities is also observed, presenting the same development as the ones reported in flat plate experiments. The disturbance growth, characterised by its root mean squares value, is found to depend not only on the turbulence level, but also on the FST length scales. Particularly, higher disturbance growth is observed for our cases with larger length scales. This behaviour is attributed to the preferred wavenumbers that can exhibit maximum transient growth. We study this boundary layer preference by projection of the flow fields at the leading edge onto optimal disturbances. Our results demonstrate that optimal disturbance growth is the main cause of growth of disturbances on the wing boundary layer.
The effect of inter-particle hydrodynamic and magnetic interactions in a magnetorheological fluid
Authors: Kumaran V.
Published: July 2022

A magnetorheological fluid, which consists of magnetic particles suspended in a viscous fluid, flows freely with well-dispersed particles in the absence of a magnetic field, but particle aggregation results in flow cessation when a field is applied. The mechanism of dynamical arrest is examined by analysing interactions between magnetic particles in a magnetic field subject to a shear flow. An isolated spherical magnetic particle undergoes a transition between a rotating state at low magnetic field and a static orientation at high magnetic field. The effect of interactions for spherical dipolar and polarisable particles with static orientation is examined for an unbounded dilute viscous suspension. There are magnetic interactions due to the magnetic field disturbance at one particle caused by the dipole moment of another, hydrodynamic interactions due to the antisymmetric force moment of a non-rotating particle in a shear flow, and a modification of the magnetic field due to the particle magnetic moment density. When there is a concentration variation, the torque balance condition results in a disturbance to the orientation of the particle magnetic moment. The net force and the drift velocity due to these disturbances is calculated, and the collective motion generated is equivalent to an anisotropic diffusion process. When the magnetic field is in the flow plane, the diffusion coefficients in the two directions perpendicular to the field direction are negative, implying that concentration fluctuations are unstable in these directions. This instability could initiate field-induced dynamical arrest in a magnetorheological fluid.
The Sardauna's Middle East: Regionalism and Backstage Politics in Nigeria's Postcolonial Diplomacy
Authors: Schler Lynn
Published: July 2022

The Middle East conflict has been identified as one of the most polarizing issues in the history of foreign relations of Nigeria during the First Republic (1960–6). The Christian-majority southern regions supported close relations with Israel, while the Muslim-majority Northern Region aligned with Arab states. The Sardauna Ahmadu Bello, Premier of the Northern Region, is remembered as particularly hostile to Israeli incursions in Nigeria. Reviewing new evidence from the Israel State Archives, this article introduces more complexity into portrayals of the Sardauna's positions. Contending with the enormous challenges of decolonization, the Sardauna continually vacillated in his approach to Middle East relations, weighing opportunities against drawbacks in establishing ties. Examining the more accommodating approach that the Sardauna adopted beyond the public eye, we gain new insights into his attempts to achieve political and economic objectives with regard to the Northern Region, while navigating the contentious political landscape of Nigeria's First Republic.
Emergency management plan for paediatric patients with tracheostomies during the coronavirus disease 2019 pandemic
Authors: Petulla B , Ho E , Sov E , Soma M
Published: July 2022

Objectives

Paediatric patients with tracheostomies are a vulnerable group. During the coronavirus disease 2019 pandemic, healthcare workers can be anxious about viral transmission from secretions and aerosols emerging from the open airway. This paper aims to share a systematic approach to decrease staff exposure and optimise care of these patients.

Methods

Three documents were developed: a generic tracheostomy management plan detailing troubleshooting; a personalised management plan with customised recommendations; and a guide for tracheostomy tube change to minimise aerosol production.

Results

The plan was distributed to 31 patients (age range, 11 months to 17 years) including 23 (74.2 per cent) with uncuffed tubes and 9 (29 per cent) on long-term ventilation. There have been 10 occasions in which the plan was utilised and influenced management.

Conclusion

A structured approach to emergency presentations during the coronavirus disease 2019 pandemic may safeguard paediatric patients from unnecessary manipulation of their tracheostomy tube, minimise viral exposure and allow provision of expeditious care.
A hybrid cable-driven parallel robot as a solution to the limited rotational workspace issue
Authors: Ennaiem Ferdaws , Chaker Abdelbadia , Sandoval Juan , Mlika Abdelfattah , Romdhane Lotfi , Bennour Sami , Zeghloul Said , Laribi Med Amine
Published: July 2022

Cable-driven parallel robots (CDPRs) are still gaining attention thanks to their interesting characteristics compared to serial or classic parallel manipulators. However, the limited range of rotation of their end-effectors reduces their application fields to predominantly translational movements. In this context, the issue of extending the rotational workspace of a CDPR while maintaining a compact robot structure is addressed in this paper. This work is motivated by the need to find the optimal CDPR for upper limb rehabilitation allowing to assist the patient’s hand along a set of prescribed tasks. Firstly, a reconfigurable robot, where the motors’ locations are movable, is proposed in order to help reaching all the prescribed poses. Although this solution presents promising results compared to classical CDPRs, it involves a sizable robot structure inadequate to rehabilitation application. To improve the obtained solution, another approach is proposed, based on combining the large translational workspace of CDPRs and the large rotational workspace of serial manipulators. The optimal structure of a hybrid robot will be considered for the prototype design.
Interlacing China and Taiwan: Tea Production, Chinese-language Education and the Territorial Politics of Re-Sinicization in the Northern Borderlands of Thailand
Authors: Hung Po-Yi
Published: July 2022

While most ethnic Chinese in northern Thailand are Thai citizens now, their everyday lives are a site where we can witness the political power entanglement of China, Taiwan and Thailand. With this in mind, this paper aims to look into the relationship between global China and overseas Chinese from the perspective of the ethnic Chinese in the northern borderlands of Thailand. The purpose is not just to disclose the multiplicity of global China in people's everyday lives, but also to complicate the picture of overseas Chinese as portrayed in top-down grand narratives about global China. I argue that the ongoing re-Sinicization in South-East Asia and the territorial geopolitics among China, Taiwan and Thailand have opened a conceptual space for the ethnic Chinese in northern Thailand to flexibly articulate themselves within the changing geopolitical economy. I use tea production and related Chinese-language education programmes, two separate but intertwined cases, to address these issues. By looking beyond the competition, conflict and dilemmas between China and Taiwan, I argue that Taiwan's previous engagement with agricultural transfer to Thailand and the rooting of pro-Taiwan identity and discourse in language education have paradoxically paved a way for China to stretch its influence into the everyday lives of the Chinese communities in the northern Thai borderlands.
A Doppler enhanced TDCP algorithm based on terrain adaptive and robust Kalman filter using a stand-alone receiver
Authors: Shao Kefan , Li Zengke , Yang Zhehua , Liu Zan , Sun Yaowen
Published: July 2022

Time-differenced carrier phase (TDCP) is a commonly used method of precise velocimetry, but when the receiver is in a dynamic or complex observation environment, the estimation accuracy is reduced. Doppler velocimetry aims at estimating instantaneous velocity, and the accuracy is restricted by the accuracy of measurement. However, in such unfavourable cases, the Doppler measurement is more reliable than the carrier phase measurement. This paper derives the relationship between Doppler observation and TDCP observation, then proposes a Doppler enhanced TDCP algorithm, for the purpose of improving the velocity estimation accuracy in dynamic and complex observation environments. In addition, considering the error caused by the constant speed state update model in the robust Kalman filter (RKF), this paper designs a terrain adaptive and robust Kalman filter (TARKF). After three experimental tests, the improved TDCP algorithm can significantly increase the speed measurement accuracy to sub-metre per second, and the accuracy can be further improved after using TARKF.
Risk factors for underlying comorbidities and complications in patients with hepatitis B virus-related acute-on-chronic liver failure
Authors: Weng Wei-zhen , Chen Jun-feng , Peng Xiao-hua , Huang Miao , Zhang Jing , Xiong Jing , Cao Hui-juan , Lin Bing-liang
Published: July 2022

Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a severe and life-threatening complication, characterised by multi-organ failure and high short-term mortality. However, there is limited information on the impact of various comorbidities on HBV-ACLF in a large population. This study aimed to investigate the relationship between comorbidities, complications and mortality. In this retrospective observational study, we identified 2166 cases of HBV-ACLF hospitalised from January 2010 to March 2018. Demographic data from the patients, medical history, treatment, laboratory indices, comorbidities and complications were collected. The mortality rate in our study group was 47.37%. Type 2 diabetes mellitus was the most common comorbidity, followed by alcoholic liver disease. Spontaneous bacterial peritonitis, pneumonia and hepatic encephalopathy (HE) were common in these patients. Diabetes mellitus and hyperthyroidism are risk factors for death within 90 days, together with gastrointestinal bleeding and HE at admission, HE and hepatorenal syndrome during hospitalisation. Knowledge of risk factors can help identify HBV-ACLF patients with a poor prognosis for HBV-ACLF with comorbidities and complications.
Denotational semantics as a foundation for cost recurrence extraction for functional languages
Authors: DANNER NORMAN , LICATA DANIEL R.
Published: July 2022

A standard informal method for analyzing the asymptotic complexity of a program is to extract a recurrence that describes its cost in terms of the size of its input and then to compute a closed-form upper bound on that recurrence. We give a formal account of that method for functional programs in a higher order language with

$\mathtt{let}$

-polymorphism. The method consists of two phases. In the first phase, a monadic translation is performed to extract a cost-annotated version of the original program. In the second phase, the extracted program is interpreted in a model. The key feature of this second phase is that different models describe different notions of size. This plays out in several ways. For example, when analyzing functions that take arguments of inductive types, different notions of size may be appropriate depending on the analysis. When analyzing polymorphic functions, our approach shows that one can formally describe the notion of size of an argument in terms of the data that is common to the notions of size for each type instance of the domain type. We give several examples of different models that formally justify various informal cost analyses to show the applicability of our approach.
Sociological approaches and the urban history of medieval England: research trends and new perspectives (2017–2022)
Authors: Harkes Rachael C.
Published: July 2022

In 2011, when Jelle Haemers looked back on a decade's worth of Ph.D. theses on urban centres in the medieval Low Countries, he identified three main trends in scholarship: the emphasis on individuals, rather than institutions; the increasing use of new methodologies, such as social network analysis (SNA) and prosopography; and the deployment of inter-disciplinary perspectives. Haemers’ intuition proved prescient; recent doctoral contributions to the historiography of medieval English towns and cities tend, generally, to fall along similar lines. In many ways, this is natural, and a testament to the enduring legacy and successes of earlier works. But, as the following discussion will elaborate, important and divergent steps have also been made, pushing our perceptions of pre-modern urban societies in new directions. Medieval urban history remains a vibrant area for study, with Ph.D. students forming an important section of its vanguard.
Teamwork within a Senior Capstone Course: Implementation and Assessment
Authors: Bayer Reşat , Turper Sedef , Woods Judy
Published: July 2022

Although senior capstone courses and projects globally are growing in popularity for undergraduate students in political science, with the potential to integrate prior curriculum and assess student learning, students generally undertake this milestone as individuals. In contrast, we present a teamwork-based capstone course wherein key student submissions—including the final project—are created in teams. Having conducted this course for several years, we describe in this article how we incorporated teamwork and demonstrate how students evaluate teamwork in in-person, online, and hybrid course formats.
The Prospective Effect of Cinnamon and Chia on Submandibular Salivary Glands After Ciprofloxacin Administration in Albino Rats (Histological, Histochemical, and Ultrastructural Study)
Authors: Abd-elmonsif Nehad M , El-Zainy Medhat A , Rabea Amany A , Fathy Mohamed Iman A
Published: July 2022

Ciprofloxacin (CPFX®) is potent fluoroquinolone but has severe side effects. Cinnamon (CIN) and chia seeds are potent antioxidants. The current work aimed to compare the effect of CIN extract and chia seeds on CPFX®-treated submandibular salivary glands (SMGs). Thirty-two male albino rats were divided into four groups: Group 1: received saline. Group 2: received CPFX®. Group 3: received CIN extract after 4 h of CPFX® administration. Group 4: received ground chia seeds after 4 h of CPFX® administration. After 10 days, histological, histochemical, and ultrastructural examinations were done. Different examinations illustrated normal features of SMG in Groups 1 and 3. Group 2 showed degenerative signs. Group 4 showed normal features in some areas. Statistical results illustrated that Group 2 had highest mean vacuolation area%. Highest mean of PAS optical density (OD) was for Group 2. Concerning mercuric bromophenol blue stain OD; Group 1 showed highest mean OD. CPFX® has the deteriorative effect on SMG structure and ultrastructure. It leads to increased levels of glycosaminoglycans (GAGs) and decreased levels of total proteins. CIN extract showed more ameliorative effect compared to chia seeds.
Protecting ocean worlds: Europa Clipper planetary protection inputs to a probabilistic risk-based approach
Authors: Smith Alvin L. , Hendrickson Ryan C.
Published: July 2022

There is increased interest in exploring planetary bodies that have ocean worlds, and planetary protection (PP) practices for spacecraft are important to avoid harmful biological contamination of these sensitive environments. In the autumn of 2018 a diverse set of subject matter experts were assembled to examine the environmental input parameters (e.g. space radiation, Europa surface turnover) and biological input parameters that are referenced by the Europa Clipper project probabilistic risk model, to assess the < 1 × 10−4 probability of contamination requirement derived from NASA Procedural Requirements 8020.12D. A joint NASA–JPL lead workshop entitled, ‘Europa Clipper Planetary Protection Workshop’ was convened on 13–15 November 2018, to validate probability model input values, current Europa Clipper PP requirements and implementation strategy, and identify future PP research topics. The three objectives for the 3 day workshop were: (1) to validate the probability of contamination modelling framework for Europa Clipper PP; (2) to agree on probability of contamination model input values, or on a plan to derive/identify appropriate model inputs and (3) to develop workshop concurrence regarding future PP research plans and their priority. Workshop participants engaged in detailed scientific and engineering discussions focusing on Clipper mission objectives and trajectories, Europan ice shell geophysics and understanding the impact of initial microbial bioburdens and spacecraft cleanliness with all three objectives being successfully completed by the end of the workshop.
Catchment Dissolved Organic Carbon Transport: A Modeling Approach Combining Water Travel Times and Reactivity Continuum
Authors: Grandi G. , Bertuzzo E.
Published: July 2022

Quantifying the transfer of organic carbon from the terrestrial to the riverine ecosystems is of crucial importance to fully appreciate the carbon cycle at the catchment, regional and global scales. In this study, we propose a framework for modeling the flux of dissolved organic carbon (DOC) from hillslopes to stream and river networks which couples a transport model based on travel time distributions with the reactivity continuum (RC) approach to model DOC degradation. We test the model by applying it to the Plynlimon catchments (UK) exploiting both weekly and high‐frequency (7‐hr interval) time‐series. We use information about chloride to get an independent estimate of water travel times using the framework of StorAge Selection functions. Following the RC model, the composition and the degradation of DOC along the flowpaths, and its consequent concentration in the streamflow, is described assuming that DOC is composed by a mixture of compounds that follows a continuous spectrum of reactivity. For the high‐frequency data set, the model is able to reproduce DOC streamflow concentrations and to capture the complex hysteretic relation between DOC concentration and discharge. Weekly data are instead not frequent enough to properly describe DOC dynamics in this catchment. The distribution of the age of the water comprised in the streamflow proves thus a key variable to predict the quantity and the reactivity of the DOC exported from soils, and the effect of hydrologic variability on this process.
Flow Strength and Bedload Sediment Travel Distance in Gravel Bed Rivers
Authors: Papangelakis E. , MacVicar B. J. , Montakhab A. F. , Ashmore P.
Published: July 2022

The quantification of bedload sediment transport in rivers is possible from statistics of individual particle displacements. However, there is a lack of empirical basis for a universal relation between particle displacement distance and hydraulic drivers. Previous work suggests that a simple linear relation exists between the energy of a flood and the mean travel distance of bedload particles. Such a relation would be advantageous, but a consistent model able to collapse the data from different rivers has not been developed. Here, we develop a predictive relation from a unique data set collected in three watersheds from a single region but contrasting hydrologic regimes due to urbanization and storm water management. Additional data from two rivers from outside the region are used to validate the model. We show that the mean of an exponential distribution of surface particle travel displacements can be reliably predicted from either the cumulative discharge or stream power exceeding the mobilization threshold, which is calibrated using field data. The strength of the relation decreases after large flood events that appear to cause tracer burial due to vertical mixing. This result indicates that the relation is most applicable for the entrainment phase of transport in which tracers are dispersing over the bed surface. Tracer movements become more challenging to predict over a long series of events due to burial and eventual tracer slowdown, but the relation remains valid for the particles located on the bed surface, making it suitable for analyzing the impact of climate and landscape changes over time.
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
Authors: Niemann Birte , Haufs-Brusberg Saskia , Puetz Laura , Feickert Martin , Jaeckstein Michelle Y. , Hoffmann Anne , Zurkovic Jelena , Heine Markus , Trautmann Eva-Maria , Müller Christa E. , Tönjes Anke , Schlein Christian , Jafari Azin , Eltzschig Holger K. , Gnad Thorsten , Blüher Matthias , Krahmer Natalie , Kovacs Peter , Heeren Joerg , Pfeifer Alexander
Published: July 2022

Brown adipose tissue (BAT) dissipates energy1,2 and promotes cardiometabolic health3. Loss of BAT during obesity and ageing is a principal hurdle for BAT-centred obesity therapies, but not much is known about BAT apoptosis. Here, untargeted metabolomics demonstrated that apoptotic brown adipocytes release a specific pattern of metabolites with purine metabolites being highly enriched. This apoptotic secretome enhances expression of the thermogenic programme in healthy adipocytes. This effect is mediated by the purine inosine that stimulates energy expenditure in brown adipocytes by the cyclic adenosine monophosphate–protein kinase A signalling pathway. Treatment of mice with inosine increased BAT-dependent energy expenditure and induced ‘browning’ of white adipose tissue. Mechanistically, the equilibrative nucleoside transporter 1 (ENT1, SLC29A1) regulates inosine levels in BAT: ENT1-deficiency increases extracellular inosine levels and consequently enhances thermogenic adipocyte differentiation. In mice, pharmacological inhibition of ENT1 as well as global and adipose-specific ablation enhanced BAT activity and counteracted diet-induced obesity, respectively. In human brown adipocytes, knockdown or blockade of ENT1 increased extracellular inosine, which enhanced thermogenic capacity. Conversely, high ENT1 levels correlated with lower expression of the thermogenic marker UCP1 in human adipose tissues. Finally, the Ile216Thr loss of function mutation in human ENT1 was associated with significantly lower body mass index and 59% lower odds of obesity for individuals carrying the Thr variant. Our data identify inosine as a metabolite released during apoptosis with a ‘replace me’ signalling function that regulates thermogenic fat and counteracts obesity.
Evaluation and comparison of three virucidal agents on inactivation of Nipah virus
Authors: Huang Yi , Xiao Shuqi , Song Donglin , Yuan Zhiming
Published: July 2022

Modern human activity is profoundly changing our relationship with microorganisms with the startling rise in the rate of emerging infectious diseases. Nipah virus together with Ebola virus and SARS-CoV-2 are prominent examples. Since COVID-19 and the West African Ebola virus disease outbreak, different chemical disinfectants have been developed for preventing the direct spread of viruses and their efficacy has also been evaluated. However, there are currently no published efficacy studies for the chemical disinfection of Nipah virus. In this study, the virucidal efficacy of three disinfectants (Micro-Chem Plus detergent disinfectant cleaner, FWD and Medical EtOH) against Nipah virus was evaluated in quantitative suspension tests including. Our results showed that the > 4 log reduction achieved for all products in inactivating Nipah virus in 15 s. Even, 19% ethanol was able to inactivate Nipah virus when applied for at least 8 min contact time. Comparative analysis displayed virucidal efficacy of each of the evaluated disinfectants against SARS-CoV-2, Ebola virus and Nipah virus, with only minor differences in working concentrations and contact times required for complete inactivation. We expect that our study can assist in decontamination in healthcare settings and high level biosafety laboratories and can be beneficial to control for emerging enveloped viruses.
The advent of thermoplasmonic membrane distillation
Authors: Santoro Sergio , Avci Ahmet H. , Politano Antonio , Curcio Efrem
Published: July 2022

The recent discoveries related to the efficient light-to-heat conversion in nanomaterials have enabled the implementation of sunlight-driven Membrane Distillation for a desalination at the water-energy nexus.
l-Proline, a resolution agent able to target both enantiomers of mandelic acid: an exciting case of stoichiometry controlled chiral resolution
Authors: Zhou Fuli , Collard Laurent , Robeyns Koen , Leyssens Tom , Shemchuk Oleksii
Published: July 2022

l-Proline is used to resolve both enantiomers of mandelic acid through a stoichiometry controlled chiral resolution.
Simple preparation of Ag-BTC-modified Co3Mo7O24 mesoporous material for capacitance and H2O2-sensing performances
Authors: Xu Lijie , Zhao Xinyu , Yu Kai , Wang Chunmei , Lv Jinghua , Wang Chunxiao , Zhou Baibin
Published: July 2022

{Co3Mo7O24}@Ag-BTC-2 was synthesized by a grinding method, and it showed excellent performance in a supercapacitor and H2O2 sensing.
Broad luminescence tuning in Mn2+-doped Rb2Zn3(P2O7)2via doping level control based on multiple synergies
Authors: Liu Qin , Dang Peipei , Zhang Guodong , Lian Hongzhou , Li Guogang , Molokeev Maxim S. , Cheng Ziyong , Lin Jun
Published: July 2022

A series of novel Mn2+-doped Rb2Zn3(P2O7)2 phosphors for tunable emission from green to orange-red due to Mn2+ preferential occupation of different crystallographic sites with an increasing Mn2+ doping level.
Dynamic effects of the bridged structure on the quantum yield of the cis → trans photoisomerization of azobenzene
Authors: Matsubara Toshiaki
Published: July 2022

A nonadiabatic molecular dynamics simulation was performed for the cis → trans photoisomerization of diindane diazocine to determine how its bridged structure results in the highest reported quantum yield for this isomerization.
Ferrocene-appended anthraquinone and coumarin as redox-active cytotoxins
Authors: Houshmand Aryan , Heroux Devon , Liu Dennis Y. , Zhou Wen , Linington Roger G. , Bally Marcel , Warren Jeffrey J. , Walsby Charles J.
Published: July 2022

Appending ferrocene to coumarin and anthraquinone promotes generation of hydroxyl radicals and modulates anticancer activity.
Theoretical insights into selective extraction of uranium from seawater with tetradentate N,O-mixed donor ligands
Authors: Luan Xue-Fei , Wang Cong-Zhi , Wu Qun-Yan , Lan Jian-Hui , Chai Zhi-Fang , Xia Liang-Shu , Shi Wei-Qun
Published: July 2022

DFT calculations demonstrate that the tetradentate N,O-mixed donor ligands are potential candidates for selective extraction of uranium from seawater.
Water soluble transition metal [Ni(ii), Cu(ii) and Zn(ii)] complexes of N-phthaloylglycinate bis(1,2-diaminocyclohexane). DNA binding, pBR322 cleavage and cytotoxicity
Authors: Khursheed Salman , Siddique Hifzur R. , Tabassum Sartaj , Arjmand Farukh
Published: July 2022

A series of water-soluble ionic complexes (1–3) were synthesized as potent anticancer agents.
Coordination mode and stability of the tetrahydroborate ligand in group 10 metal pincer complexes
Authors: Chang Jiarui , Ding Man , Kang Jia-Xin , Zhang Jie , Chen Xuenian
Published: July 2022

The coordination mode and stability of the tetrahydroborate ligand in group 10 metal pincer complexes are significantly influenced by the pincer platform and the electronic properties of the metal centre.
Rapid synthesis process and characterization for high purity sodium thioantimoniate nonahydrate
Authors: Bertrand A. , Paecklar A. , Barbier T. , Gascoin F.
Published: July 2022

For the first time, Na3SbS4·9H2O, also known as Schlippe's salt, has been synthesized through high-energy ball milling.
Sulfinyl-aminotroponiminates: alkali- (Li, Na, K) and heavy-metal (Bi) complexes
Authors: Hanft Anna , Rottschäfer Dennis , Müller Victoria , Weinberger Pascal , Radacki Krzysztof , Xie Xiulan , Lichtenberg Crispin
Published: July 2022

Sulfinyl-substituted aminotroponiminate (ATI) complexes of the alkali metals Li–K and the heavy metal bismuth have been isolated and characterised. The sulfinyl group affects their coordination and redox properties in the solid state and in solution.
ANN-LIBS analysis of mixture plasmas: detection of xenon
Authors: Saeidfirozeh Homa , Myakalwar Ashwin Kumar , Kubelík Petr , Ghaderi Amirhossein , Laitl Vojtěch , Petera Lukáš , Rimmer Paul B. , Shorttle Oliver , Heays Alan N. , Křivková Anna , Krůs Miroslav , Civiš Svatopluk , Yáñez Jorge , Képeš Erik , Pořízka Pavel , Ferus Martin
Published: July 2022

We developed an artificial neural network method for characterising crucial physical plasma parameters (i.e., temperature, electron density) in a fast and precise manner that mitigates common issues arising in evaluation of LIBS spectra.
Ensemble latent assimilation with deep learning surrogate model: application to drop interaction in a microfluidics device
Authors: Zhuang Yilin , Cheng Sibo , Kovalchuk Nina , Simmons Mark , Matar Omar K. , Guo Yi-Ke , Arcucci Rossella
Published: July 2022

Upper: predictions using the machine learning surrogate model with ensemble latent assimilation; bottom: recorded experimental images of each corresponding timestep.
A review of recent advances in metal ion hydrogels: mechanism, properties and their biological applications
Authors: Zhang Xin , Tang Yuanhan , Wang Puying , Wang Yanyan , Wu Tingting , Li Tao , Huang Shuo , Zhang Jie , Wang Haili , Ma Songmei , Wang Linlin , Xu Wenlong
Published: July 2022

The mechanisms, common properties and biological applications of different types of metal ion hydrogels are summarized.
Enantioselective synthesis of isoxazole-containing spirooxindole tetrahydroquinolines via squaramide-catalysed cascade reactions
Authors: Li Tong-Hao , Niu Cheng , Du Da-Ming
Published: July 2022

A highly efficient squaramide-catalysed asymmetric cascade aza-Michael/Michael reaction for enantioselective synthesis of isoxazole-containing spirooxindole tetrahydroquinolines with high stereoselectivities was developed.
Effect of solvent isomers on the gelation properties of tri-aryl amine organogels and their hybrid thermoreversible gels with poly[vinyl chloride]
Authors: Xiao Yao , Dominique Collin , Odile Gavat , Alain Carvalho , Emilie Moulin , Nicolas Giuseppone , Jean-Michel Guenet
Published: July 2022

The gelation properties of tri-aryl amine (TATA) in two isomers of dichlorobenzene, namely ortho-dichlorobenzene (o-DCB) and meta-dichlorobenzene (m-DCB), have been studied by calorimetry for mapping out the temperature–concentration phase diagram.
Whole-genome survey and phylogenetic analysis of Gadus macrocephalus
Authors: Ma Yiqing , Lou Fangrui , Yin Xiaofei , Cong Bailin , Liu Shenghao , Zhao Linlin , Zheng Li
Published: July 2022

Gadus macrocephalus (Pacific cod) is an economically important species on the northern coast of the Pacific. Although numerous studies on G. macrocephalus exist, there are few reports on its genomic data. Here, we used whole-genome sequencing data to elucidate the genomic characteristics and phylogenetic relationship of G. macrocephalus. From the 19-mer frequency distribution, the genome size was estimated to be 658.22 Mb. The heterozygosity, repetitive sequence content and GC content were approximately 0.62%, 27.50% and 44.73%, respectively. The draft genome sequences were initially assembled, yielding a total of 500,760 scaffolds (N50 = 3565 bp). A total of 789,860 microsatellite motifs were identified from the genomic data, and dinucleotide repeat was the most dominant simple sequence repeat motif. As a byproduct of whole-genome sequencing, the mitochondrial genome was assembled to investigate the evolutionary relationships between G. macrocephalus and its relatives. On the basis of 13 protein-coding gene sequences of the mitochondrial genome of Gadidae species, the maximum likelihood phylogenetic tree showed that complicated relationships and divergence times among Gadidae species. Demographic history analysis revealed changes in the G. macrocephalus population during the Pleistocene by using the pairwise sequentially Markovian coalescent model. These findings supplement the genomic data of G. macrocephalus, and make a valuable contribution to the whole-genome studies on G. macrocephalus.
Implementing a Remote Synchronous Mindfulness Program for Master of Science in Speech-Language Pathology Students: Preliminary Findings
Authors: Medina Angela M. , Mead Jean S. , Prokopowicz Patrycja A. , Ahmed Fiaza , Basanez Milena , Medellin Daniela , Sommer Chelsea L.
Published: July 2022

Purpose:

The purpose of this study was to explore outcomes of a remote synchronous mindfulness program (RSMP) for Master of Science in Speech-Language Pathology (MS-SLP) students.

Method:

Twenty-nine MS-SLP students initially enrolled in the program and completed the pretest, which consisted of demographic questions, the Perceived Stress Scale (PSS-10), and open-ended questions about mindfulness. The posttest, which was completed by 26 participants, included the PSS-10 and additional open-ended questions. Data generated by three questions on benefits and challenges of the program were analyzed using thematic analysis procedures. Pre- and posttest PSS-10 scores for 24 participants were calculated and statistically analyzed.

Results:

Three major themes that arose from the pretest data question about expected benefits were “Stress Reduction,” “Mental and Physical Health Improvements,” and “Personal and Professional Development.” The posttest data, generated from an open-ended question about perceived benefits, gave rise to three themes: “Internal Growth,” “Calming Strategies,” and “Knowledge of Mindfulness Practice.” Posttest data about the challenges of practicing mindfulness yielded four themes: “Racing mind,” “Scheduling,” “Pervasiveness of anxiety and stress,” and “Finding a quiet place at home.” No statistically significant differences were found between the PSS-10 scores before and after participation in this study.

Conclusions:

These findings suggest that the MS-SLP students who engaged in the RSMP experienced comparable outcomes to communication sciences and disorders (CSD) students who participated in face-to-face mindfulness programs. Therefore, the remote modality may be a viable option for providing mindfulness practice as a mental health resource for CSD students.
An elliptical accretion disk following the tidal disruption event AT 2020zso
Authors: Wevers T. , Nicholl M. , Guolo M. , Charalampopoulos P. , Gromadzki M. , Reynolds T. M. , Kankare E. , Leloudas G. , Anderson J. P. , Arcavi I. , Cannizzaro G. , Chen T.-W. , Ihanec N. , Inserra C. , Gutiérrez C. P. , Jonker P. G. , Lawrence A. , Magee M. R. , Müller-Bravo T. E. , Onori F. , Ridley E. , Schulze S. , Short P. , Hiramatsu D. , Newsome M. , Terwel J. H. , Yang S. , Young D.
Published: July 2022

Aims. The modelling of spectroscopic observations of tidal disruption events (TDEs) to date suggests that the newly formed accretion disks are mostly quasi-circular. In this work we study the transient event AT 2020zso, hosted by an active galactic nucleus (AGN; as inferred from narrow emission line diagnostics), with the aim of characterising the properties of its newly formed accretion flow.

Methods. We classify AT 2020zso as a TDE based on the blackbody evolution inferred from UV/optical photometric observations and spectral line content and evolution. We identify transient, double-peaked Bowen (N III), He I, He II, and Hα emission lines. We model medium-resolution optical spectroscopy of the He II (after careful de-blending of the N III contribution) and Hα lines during the rise, peak, and early decline of the light curve using relativistic, elliptical accretion disk models.

Results. We find that the spectral evolution before the peak can be explained by optical depth effects consistent with an outflowing, optically thick Eddington envelope. Around the peak, the envelope reaches its maximum extent (approximately 1015 cm, or ∼3000–6000 gravitational radii for an inferred black hole mass of 5−10 × 105 M⊙) and becomes optically thin. The Hα and He II emission lines at and after the peak can be reproduced with a highly inclined (i = 85 ± 5 degrees), highly elliptical (e = 0.97 ± 0.01), and relatively compact (Rin = several 100 Rg and Rout = several 1000 Rg) accretion disk.

Conclusions. Overall, the line profiles suggest a highly elliptical geometry for the new accretion flow, consistent with theoretical expectations of newly formed TDE disks. We quantitatively confirm, for the first time, the high inclination nature of a Bowen (and X-ray dim) TDE, consistent with the unification picture of TDEs, where the inclination largely determines the observational appearance. Rapid line profile variations rule out the binary supermassive black hole hypothesis as the origin of the eccentricity; these results thus provide a direct link between a TDE in an AGN and the eccentric accretion disk. We illustrate for the first time how optical spectroscopy can be used to constrain the black hole spin, through (the lack of) disk precession signatures (changes in inferred inclination). We constrain the disk alignment timescale to > 15 days in AT2020zso, which rules out high black hole spin values (a < 0.8) for MBH ∼ 106 M⊙ and disk viscosity α ≳ 0.1.
The Effects of Erythrina subumbrans (Hassk.) Merr. Leaves Extract on Nicotine Withdrawal Syndrome and β2 nAChRs Expression in The Ventral Tegmental Area of Rats
Authors: Risdiana Nurvita , Susilowati Rina , Nurwening Sholikhah Eti , Partadiredja Ginus
Published: July 2022

Erythrina subumbrans (Hassk.) Merr. is an alkaloid plant with dihydro-β-erythroidine (DhβE) content which is considered to block α4β2 nAChRs subtype and, therefore, may suppress the desire to use nicotine. This study aimed to investigate these possible effects of E.subumbrans (Hassk.) Merr. extract on nicotine withdrawal syndrome and β2 nAChRs expression in rats' ventral tegmental area (VTA). The rats were divided into six groups, i.e., control (OO), nicotine treated (NO), nicotine, and E. subumbrans (Hassk.) Merr.-treated (NE 100, NE 200, NE 400), and E. subumbrans (Hassk.) Merr.-treated (OE 200) groups. Nicotine was given ad libitum via drinking water with a step-wise increase of dosage every four days for 30 days. Somatic and affective signs were observed during the dark cycle of 24 hours abstinent period (days 31and 46). The expression of β2 nAChRs in the VTA was examined semi-quantitatively. It has been found that the rearing behavior of the NE 100 group was fewer on day 46 than on day 31. The body scratching behavior of the NE 100 group was fewer than that of the OO group on day 46. The front paws and penile licking behaviors of the NE 100 group were fewer than those of the NO group on day 46. The open arm entries of the NO group were fewer than that of the NE 200 group on day 46. The β2nAChRs expression of the NO group was lower than that of the OO group. E. Subumbrans (Hassk.) Merr. at a dosage of 100mg/kg BW may decrease some somatic signs of nicotine withdrawal syndrome.
The Influence of the Factors of the Period and Place of Quarantine and Stigmatization on the Resilience of COVID-19 Survivors of Nurses
Authors: Winugroho Tri , Budiarto Arief , Sarpono  , Imansyah Mulya , Hidayat Arip
Published: July 2022

As health workers, nurses at the forefront of the COVID-19 pandemic tend to be very prone to suffer both physical and mental health problems due to workloads and other factors during the Covid-19 pandemic.This study aimed to analyze the impact of factors such as length and place of quarantine and stigma on the resilience among COVID-19 survivors nurses. This research uses a quantitative descriptive technique and a cross-sectional approach. The google form questionnaire method is used as an instrument in data collection and processed utilizing multi regression analysis. The research output showed that 58.7% of nurses who survived COVID-19 had moderate resilience, 25.4% had high resilience, and 15.9% had low resilience. The long quarantine period results lead to an average of 85.7%, 11.1% for the long quarantine period, and 3.2% for the short quarantine period, with an influence value of 7.1%. The result of stigmatization leads to moderate 71.4%, high 15.9%, and 12.7% low with an influence value of 94.7%. By getting in multiple regression analysis p-values of 0.003 < 0.05, the F test value (5,120) > F tab (3.09) and it is summarized that place, the length of quarantine and stigmatization simultaneously influence the resilience of COVID-19 survivor nurses. It influences the value of the determinant coefficient (R2) of 20.7%, and the rest is influenced by factors outside the study, such as gender, age and academic degree. These findings suggest that stigma and place of quarantine factors are important predictors that affect mental toughness and quality of life to increase immunity for nurses themselves.
Online physiology practicum during the COVID-19 pandemic at Faculty of Medicine Universitas Pembangunan Nasional Veteran Jakarta
Authors: Bustamam Nurfitri
Published: July 2022

During the COVID-19 pandemic, student learning activities at the Faculty of Medicine Universitas Pembangunan Nasional Veteran Jakarta should be implemented online. Therefore, a learning method of physiology practicum was designed to achieve the learning objectives. One week before the online meeting, students in small groups are assigned to make a video recording of the physiology practicum at home. At online meetings, first, the students have to listen to an introduction related to the theory underlying the practicum. After that, they played the recorded video, followed by a discussion about the results of the physiology practicum. This study aimed to describe student perceptions related to the learning process. A questionnaire with a 4-point Likert scale and open-ended questions were used to obtain student perceptions of the learning process, including the practicum guide, video making, introductions, and discussions. Students appreciate online physiology practicum because it is easy to implement, fun, and increases their understanding as they are required to explain the physiology practicum they did with the underlying theory. It can be concluded that this method can be used as an alternative physiology practicum.
Hygiene in der Dermatologie: SARS-CoV-2 und weitere Virus-Varianten
Authors: Schlatterer Kathrin , Maxeiner Horst-Günter , Zouboulis Christos C. , Daeschlein Georg
Published: July 2022

Die COVID-19-Pandemie hat weltweit erhebliche Beeinträchtigungen des Lebens und Arbeitens mit sich gebracht. Mit dem Beginn der Impfungen steigt die Hoffnung auf eine Kehrtwende. Dennoch sind COVID- und Intensivstationen in den Kliniken nach wie vor erheblich belastet. Häufig muss in den Kliniken aus Kapazitätsgründen auch dermatologisches Fachpersonal zur Betreuung von COVID-19-Patienten herangezogen werden. Dies führte dazu, dass im Verlauf der Pandemie dermatologische Manifestationen von COVID-19 erkannt und näher klassifiziert werden konnten. Differenzierte Hygienekonzepte, insbesondere die der Händehygiene, bringen jedoch ein weiteres, mit der Pandemie-assoziiertes dermatologisches Problem zum Vorschein: die Ausbildung von Handekzemen. Dies ist nicht nur auf medizinische Berufe beschränkt und zeigt daher eine mögliche übergeordnete Bedeutung der Dermatologie im Rahmen von zukünftigen Pandemiestrategien.