bluuebunny/crossref_metadata_2025 huggingface dataset:
Avrupa Birliği Ülkelerinin Boşanma Oranı Analizi
Authors: Kıral Ersin
Published: April 2018

Bu makale Markov zincir
modelini kullanarak kaba boşanma oranlarını tahmin etmektedir. Markov modelleri
27 Avrupa Birliği ülkesinin boşanma oranları için oluşturulmuştur. Boşanma
oranları, başlangıç olasılık matrisi ve geçiş olasılığı matrisinin çarpımı ile
tahmin edilir. Tahminlerin limit matrisleri bulunmuştur. Bu çalışmanın temel
sonuçları şunlardır: i) 2015 yılı itibarıyla üst kategoride gerçekleşen boşanma
oranlarının uzun vadede aynı kategoride kalması. ii) Sadece Belçika’nın kaba
boşanma hızı, mutlaka AB 2015 ortalamasının üzerinde gerçekleşecek ve durağan
kalacaktır. iii) Üç ve dört kategoriye sahip Markov modellerine dayanılarak,
2018 boşanma oranları büyük olasılıkla daha düşük kategorilerde gerçekleşecek
ve durağan hale gelecektir, iv) Türkiye'nin ham kaba boşanma hızı uzun vadede kesinlikle
AB 27'nin 2015 ortalamasının altında kalacaktır ve v) Beş kategori ile
oluşturulan Markov modellerine göre başlangıç boşanma olasılığı üst
kategorilerde olan ülkelerin boşanma hızının üst kategorilerde ve başlangıç
olasılığı alt kategorilerde olan ülkelerin boşanma hızının ise alt
kategorilerde durağanlaşacaktır.
Perturbation analysis of a matrix differential equation ẋ = ABx
Authors: Isabel García-Planas M. , Klymchuk Tetiana
Published: April 2018

Two complex matrix pairs (A, B) and (A′, B′) are contragrediently equivalent if there are nonsingular S and R such that (A′, B′) = (S
−1
AR, R
−1
BS). M.I. García-Planas and V.V. Sergeichuk (1999) constructed a miniversal deformation of a canonical pair (A, B) for contragredient equivalence; that is, a simple normal form to which all matrix pairs (A + A͠, B + B͠) close to (A, B) can be reduced by contragredient equivalence transformations that smoothly depend on the entries of A͠ and B͠. Each perturbation (A͠, B͠) of (A, B) defines the first order induced perturbation AB͠ + A͠B of the matrix AB, which is the first order summand in the product (A + A͠)(B + B͠) = AB + AB͠ + A͠B + A͠B͠. We find all canonical matrix pairs (A, B), for which the first order induced perturbations AB͠ + A͠B are nonzero for all nonzero perturbations in the normal form of García-Planas and Sergeichuk. This problem arises in the theory of matrix differential equations ẋ = Cx, whose product of two matrices: C = AB; using the substitution x = Sy, one can reduce C by similarity transformations S
−1
CS and (A, B) by contragredient equivalence transformations (S
−1
AR, R
−1
BS).
Reflexões sobre a Produção de Espaços de Memória em Contextos de Justiça de Transição: o caso do Memorial da Resistência de São Paulo
Authors: Trindade Talita Andrade , Costa Alessandra De Sá Mello da
Published: April 2018

O objetivo deste artigo é apresentar algumas reflexões sobre a dinâmica entre organizações, memória e justiça de transição em países da América do Sul. Para isso, discutiremos o processo de constituição e legitimação de locais de memória de resistência, tendo como referência o caso brasileiro do Memorial da Resistência de São Paulo, a partir de dados coletados de fontes documentais e orais, além de visitas técnicas realizadas ao espaço do Memorial.
Flexibilidade Organizacional e Vivências de Prazer-Sofrimento: um ensaio teórico
Authors: Nascimento Monique , Helena Livramento Dellagnelo Eloise , Birochi Renê
Published: April 2018

Este ensaio teórico tem por objetivo discorrer a respeito das implicações da flexibilidade organizacional nas vivências de prazer-sofrimento do trabalhador. Por meio deste estudo foi possível sugerir que o atual discurso de flexibilidade organizacional, liberdade oferecida ao trabalhador e maiores vivências de prazer, pode se tratar da legitimação da dominação burocrática, adaptada a um novo contexto econômico. Nesse sentido, ressalta-se a potencialidade que os estudos organizacionais possuem na produção de um conhecimento que auxilie na subversão do sofrimento em prazer, e propõe-se a reflexão das atuais práticas hegemônicas tanto em nível organizacional quanto global para que se tente superar as atuais instrumentalidades em prol de ambientes de trabalhos e organizações mais salutares.
Doenças Raras, Medicamentos Órfãos: reflexões sobre o Dark Side das organizações da indústria farmacêutica
Authors: Piret Christiane Nery Silva , De Oliveira Medeiros Cintia Rodrigues
Published: April 2018

Neste artigo teórico, nosso objetivo é ponderar sobre a atuação da indústria farmacêutica e do Estado brasileiro, quanto ao desenvolvimento e à oferta de medicamentos para o tratamento das doenças raras, na perspectiva do dark side das organizações. Ao fazermos isso, chamamos atenção para outras práticas corporativas que ocorrem nesse setor e que trazem implicações para a sociedade em geral.  Nossa contribuição reside em estimular pesquisas sobre a indústria farmacêutica que se orientem para a compreensão de questões raramente consideradas em pesquisas no campo dos estudos organizacionais, como, por exemplo, o poder e influência desse setor em governos, mercados e instituições.
Tokat İlin’deki Uzun Yıllar Yağış Parametrelerinin CLIGEN Yağış Modeli ile Değerlendirilmesi
Authors: DEMİR Saniye , OĞUZ İrfan , CİBA Ömer Faruk
Published: April 2018

Bu çalışmada, Tokat meteoroloji istasyonundan 2005-2015 yıllarına ait günlük yağış verileri,CLIGEN yağış modeli kullanılarak tahmin edilmiştir. Gözlenen ve tahmin edilen günlük, aylık ve yıllıkyağışların istatistiksel analizleri (ortalama, standart sapma, ve çarpıklık) karşılaştırılmıştır. Elde edilensonuçlardan, gözlenen ve tahmin edilen yağış verileri arasındaki ilişkinin istatistiksel olarak önemsizolduğu görülmüştür. CLIGEN özellikle ilkbahar ve kış aylarında günlük yağış verilerini gözlenendeğerin hafif altında tahmin etme eğilimdedir. Yıllık toplam ortalama ve aylık ortalama yağışları isetahmin etmede oldukça yüksek bir performans göstermiştir.
Research on the migration patterns of sea-land transitional zone in the coastal area of Longkou and Zhaoyuan
Authors: Li Changsuo , Jia Chao , Zhu Henghua , Yu Weijiang
Published: April 2018

Sea-level rise due to global warming and over-exploitation of groundwater resources in coastal areas will induce seawater intrusion into inland groundwater which is leading to the migration of the transition zone, and is affecting the security of regional social economy and water resources. Taking the blue economic zone of Shandong Peninsula as the research background, selecting the coastal area of Longkou and Zhaoyuan as the study area, this paper firstly depicts the groundwater flow field pattern in the research area, and then carries out the quantitative analysis for the migration patterns of the transition zone under changing groundwater levels. The results demonstrate that the width of sea-land transitional zone in the research area is about 1.5–4.5 km. The groundwater level is higher, the migration speed of the sea-land transitional zone is smaller. The results are of significance to study the migration of the sea-land transitional zone in the blue economic zone of Shandong peninsula.
Impact of land use/cover change on the relationship between precipitation and runoff in typical area
Authors: Li Bao-qi , Xiao Wei-hua , Wang Yi-cheng , Yang Ming-zhi , Huang Ya
Published: April 2018

To study the impact of land use/cover change (LUCC), the relationship between precipitation and runoff was investigated. Our main objective was to ensure reasonable development, management, and sustainable utilization of water resources at a watershed scale. To investigate the relationship between precipitation and runoff, a SWAT (Soil and Water Assessment Tool) model was developed by analyzing LUCC in Naoli River basin. Then, runoff response was analyzed under different LUCC conditions. The contribution coefficient of different land use types to runoff was calculated. The results of this research study are as follows. From 1986 to 2014, dry land, forest land, paddy fields, and unused land were the major land use types, accounting for more than 93% of the total catchment. On the other hand, grass land, building land, and water bodies accounted for a small proportion. Among the four main land use types, the contribution coefficient of forest land was 3.10 mm·km−2. This indicates that forest land was suitable for runoff generation. The contribution coefficient of dry land, unused land (fluvial wetland in Naoli River basin), and paddy field are −0.11, −0.37, and −0.83 mm·km−2, respectively. This implies that these three land use types were adverse factors for runoff generation.
Use of life cycle assessment to evaluate environmental impacts associated with the management of sludge and biogas
Authors: do Amaral Karina Cubas , Aisse Miguel Mansur , Possetti Gustavo Rafael Collere , Prado Marcelo Real
Published: April 2018

Upflow anaerobic sludge blanket (UASB) reactors used in sewage treatment generate two by-products that can be reused: sludge and biogas. At the present time in Brazil, most of this resulting sludge is disposed of in sanitary landfills, while biogas is commonly burned off in low-efficiency flares. The aim of the present study was to use life cycle assessment to evaluate the environmental impacts from four different treatment and final destination scenarios for the main by-products of wastewater treatment plants. The baseline scenario, in which the sludge was sanitized using prolonged alkaline stabilization and, subsequently, directed toward agricultural applications and the biogas destroyed in open burners, had the most impact in the categories of global warming, terrestrial ecotoxicity, and human non-carcinogenic toxicity. The scenario in which heat resulting from biogas combustion is used to dry the sludge showed significant improvements over the baseline scenario in all the evaluated impact categories. The recovery of heat from biogas combustion decreased significantly the environmental impact associated with global warming. The combustion of dried sludge is another alternative to improve the sludge management. Despite the reduction of sludge volume to ash, there are environmental impacts inherent to ozone formation and terrestrial acidification.
Association of minor heart anomalies with risks of sudden cardiac death
Authors: Kuznetsov V. , Soldatova A. , Fanakov A.
Published: April 2018

The review focuses on the analysis of study results related to a possible arrhythmogenic effect of minor heart abnormalities and their significance in the stratification of sudden cardiac death risks. Risk stratification of sudden cardiac death is a challenging problem of modern cardiology. Ventricular arrhythmias followed by asystolia are considered to be the main mechanisms of sudden cardiac death development. The incidence of sudden cardiac death is not high in general population but in absolute values it is significantly higher than that in high risk patients. Therefore, additional identification of sudden cardiac death risks in general population and prevention measures seem to be of special interest. Some researchers think that connective-tissue dysplasia followed by the formation of minor heart abnormalities might serve as a potential substrate for arrhythmia development and describe their arrhythmogenic effect. However, the association of minor heart abnormalities with sudden cardiac death risks is not well studied. The literature gives some data on sudden cardiac death incidence in some connective-tissue pathologies, but no variants of minor heart abnormalities leading to sudden cardiac death are described both in domestic and foreign literature. Also, the patients with these pathologies are not included in the sudden cardiac death high risk group.Received 14 November 2017. Revised 4 December 2017. Accepted 19 December 2017.Funding: The study was done with support of Tyumen Cardiology Research Center.Conflict of interest: Authors declare no conflict of interest.Author contributionsConception and study design: V.A. KuznetsovData collection and analysis: A.M. Soldatova, A.V. Fanakov Drafting the article: A.M. SoldatovaCritical revision of the article: V.A. Kuznetsov, A.M. Soldatova Literature review: A.M. Soldatova, A.V. FanakovFinal approval of the version to be published: V.A. Kuznetsov, A.M. Soldatova, A.V. Fanakov
Carotid endarterectomy in acute ischemic stroke
Authors: Kazantsev A. , Burkov N. , Tarasov R. , Anufriev A. , Shabaev A. , Ruban E. , Mironov A. , Heraskov V.
Published: April 2018

Currently, there are no clear domestic and foreign recommendations for cerebral revascularization, also missing is a definite decision on determining the timing and possibility of carotid endarterectomy in acute ischemic stroke. A set of measures aiming at obtaining a satisfactory outcome of carotid endarterectomy in the acute ischemic cerebrovascular event is developed. To prevent hyperperfusion complications, a temporary shunt, low doses of unfractionated heparin, adequate antiplatelet, hypotensive and lipid-lowering therapy are used. The main advantages and disadvantages of all modern methods of surgical treatment of this condition are presented.Received 22 August 2017. Revised 7 December 2017. Accepted 11 December 2017.Funding: The study was supported by the Siberian Branch of Russian Academy of Sciences within the framework of the fundamental research package program.Conflict of interest: Authors declare no conflict of interest.Author contributionsDrafting the article: A.N. KazantsevResources: A.R. ShabayevArtistic design: N.N. BurkovCritical revision of the article: A.I. Anufriyev, A.V. Mironov, V.Yu. KheraskovSurgical treatment: A.N. KazantsevAssistance in surgery: N.N. Burkov, A.R. ShabayevRevascularization tactic selection: A.I. Anufriyev, A.V. Mironov, V.Yu. KheraskovNeurological examination: E.V. RubanFinal approval of the version to be published: A.N. Kazantsev, N.N. Burkov, R.S. Tarasov, A.I. Anufriyev, A.R. Shabayev, E.V. Ruban, A.V. Mironov,V.Yu. Kheraskov
Nós difíceis de desatar: reaberturas do passado e sobreposições de narrativas patrimoniais sobre a presença negra em Joinville (SC)
Authors: Machado Diego Finder
Published: April 2018

Este artigo problematiza performances que, ao tensionar reaberturas das interpretações sobre o passado, sobrepuseram novas narrativas às narrativas patrimoniais consolidadas em Joinville. Dois exemplos, a comemoração da presença de negros entre os sepultados no Cemitério do Imigrante e a lavagem ritual do Monumento ao Imigrante, conduzem um debate a respeito dos nós convocadores de “patrimonialidades”, atos que sugerem outras possibilidades patrimoniais. Tais performances buscaram dar a ver diferenças culturais e reivindicaram políticas de memória que considerem anseios de reparação a grupos sociais historicamente minorizados e invisibilizados.
Quality Assessment of Prosthetic Rehabilitation Using Aesthetic Fixed Restorations
Authors: Ozhohan Zinovii , Biben Andrii
Published: April 2018

The objective of the research was to study and assess the quality of prosthetic treatment using aesthetic fixed restorations.Materials and methods. The study included 79 patients without a comorbidity who underwent prosthetic rehabilitation. All the patients were divided into 3 groups: Group I included 25 patients with metal-plastic restorations; Group II comprised 34 patients with porcelain-fused-to-metal restorations; Group III consisted of 20 patients with a combined occlusal surface of prosthetic restorations. The patients were observed 6 months after prosthetic repair. Only patients with single molar and premolar crowns were examined. Bridge prostheses were not taken into account in order to eliminate the effect of masticatory force redistribution on the abutment crowns.Results. In Group I, 11 (44%) patients were satisfied with the results of prosthetic treatment. In Group II, 25 (78.12%) patients reported that they were satisfied with their treatment. In Group III, there were 17 (85%) patients satisfied with their outcome. However, the patients’ complaints are often subjective and do not fully reflect the objective state of the dentoalveolar system. An objective examination revealed that in indirect restorations, marginal periodontium pathology is typical. Conclusions. Aesthetic fixed restorations with a combined occlusal surface have demonstrated good clinical results, even at long-term follow-up. Combining positive properties of two different construction materials, namely zirconium dioxide and ceramics, they reduce the risk of complications such as marginal periodontium pathology and chipping along the occlusal surface as well as contribute to minimal abrasion of the occlusal surfaces of the antagonistic teeth. We cannot recommend metal-plastic restorations due to their low clinical effectiveness, poor aesthetic qualities as well as a high level of marginal periodontium pathology.
Dynamics of Proteo- and Fibrinolytic Activity in Brain Structures of Rats with Diabetes Mellitus Complicated by Carotid Ischemia-Reperfusion
Authors: Tkachuk O. , Povar M.
Published: April 2018

The imbalance in the protease-antiprotease system is an integral part of the pathogenesis of acute disorder of cerebrovascular circulation and diabetes mellitus (DM), but its manifestations in the complication of diabetes by ischemia-reperfusion of the brain have not been investigated yet.The objective of the work – is to study the dynamics of carotid ischemia-reperfusion effect on the proteo- and fibrinolytic activity in brain structures of rats with experimental DM.Rats with the four-month streptozotocin DM were modeled bilateral carotene ischemia during 20 minutes. In homogenates of brain structures, indicators of proteo- fibrinolytic activity were determined after 1 hour from the beginning of reperfusion and during the 12th day of the post-ischemic period.In the absence of DM, the proteolytic activity of all or individual indicators is increased in both periods of the post-ischemic period in the cortex of the frontal and occipital lobes, the fields of hippocampus CA2 and CA3, and during the 12th day in the field CA1. In rats with diabetes, in all brain structures, there are no changes in the lysis of azo-albumin and azo-casein in both terms of observation and lysis of collagen progressively decreases.In rats without DM in the cortex of the studied particles, fields of the hippocampus CA1 and CA2, all or separate indices of fibrinolytic activity are increased in both periods of the post-ischemic period, in the field CA3 – all indices at the 12th day. In the presence of diabetes in the cortex of both studied lobes and the field CA1, the fibrinolytic activity decreases in the late post-ischemic period, in the fields of CA2 and CA3 – during both observation periods.Conclusion. In the brain structures under investigation at both time intervals, the DM eliminates the reaction of low and high molecular weight proteins to the ischemia-reperfusion and suppresses fibrinolytic activity.
FUNDAMENTOS E PRÁTICAS DA EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA: REFLEXÕES E PROPOSTAS DE ESTUDO A PARTIR DE UM MESTRADO PROFISSIONAL
Authors: Freire Emerson , Batista Sueli Soares
Published: April 2018

A expansão dos cursos em Educação Profissional e Tecnológica (EPT) nos últimos anos tem trazido desafios significativos nessa área, seja na rede pública ou privada. Dentre eles está o estabelecimento de programas de pós-graduação que permitam formar docentes,gestores e pesquisadores voltados para a realidade da EPT, conhecendo seus limites e possibilidades. Mais ainda, trata-se também de criar perspectivas de leitura, reflexões e estudos nessa modalidade de ensino. A partir da experiência docente e em pesquisa em EPT dentro do Programa de Mestrado Profissional em Gestão e Desenvolvimento da Educação Profissional, numa instituição pública paulista que atua na formação técnica e tecnológica desde 1969, os autores propõem neste artigo uma dessas possíveis perspectivas, considerando algumas trilhas básicas de investigação levantadas no contexto da arquitetura curricular de uma disciplina intitulada Fundamentos e Práticas da EPT. Parte-se da hipótese de que é necessário conhecer os fundamentos epistemológicos das relações entre educação e trabalho; problematizar o papel da EPT no atual contexto do desenvolvimento tecnocientífico, compreender as interfaces entre educação, sociedade e tecnologia a partir dos estudos da historiografia da Educação Profissional e Tecnológica,identificando as mudanças e permanências na sua fundamentação legal
TORNAR-SE EDUCADORA/PROFESSORA – PALAVRAS QUE CONTAM COMO FOI!
Authors: Costa Conceição Leal , Nunes Sandra
Published: April 2018

Neste texto partilhamos, particularmente, vivências e dinâmicas investigativas ocorridas durante a profissionalização no Curso de Mestrado em Educação Pré-escolar e Ensino do 1º Ciclo do Ensino Básico. O conceito de avaliação (FERNANDES, 2008) entrelaçou teoria e prática na intervenção pedagógica. A pesquisa biográfica (DELORY MOMBERGER, 2012; JOSSO, 2002), que inclui o conceito de mediação biográfica (PASSEGGI, 2008), orientou os processos de investigação, também guiados pelo conceito de isomorfismo pedagógico (NIZA,2009). Priorizando a investigação-formação e a participação, a narrativa global e retrospectiva mostrou que o papel dos participantes não foi fixo no desenvolvimento daquele projeto e que alguns contornos se alteraram no espaço/tempo de fazer. Observando, escutando, recordando, atuando e escrevendo, aprendemos de nós e das crianças, da e na profissão. A participação afastou posturas tradicionais do investigador e as narrativas tomaram parte numa construção de saberes em que todos tivemos voz.
O MESTRADO PROFISSIONAL EM EDUCAÇÃO E A REPERCUSSÃO DOS RELATÓRIOS CRÍTICOREFLEXIVOS À LUZ DE PAULO FREIRE
Authors: Selau Bento , Hammes Lúcio Jorge , Gritti Silvana Maria
Published: April 2018

Este trabalho tem como objetivo identificar as repercussões da execução dos Relatórios Crítico-Reflexivos, construídos no âmbito da modalidade de mestrado profissional do Programa de Pós-Graduação em Educação da Universidade Federal do Pampa (PPGEdu/UNIPAMPA), à luz de conceitos freireanos. Trata-se de uma pesquisa qualitativa, que utilizou a abordagem da pesquisa documental. Coletaram-se, aleatoriamente, oito trabalhos de conclusão de curso e os dados foram trabalhados pela análise textual discursiva. As repercussões evidenciam a proximidade das categorias freireanas, estabelecendo um diálogo fecundo entre a teoria e a prática, construindo alternativas e afirmando uma autonomia que não é concedida e nem tutelada, mas que se constrói no fazer-se. Os resultados apontam que a metodologia da pesquisa no PPGEdu apresenta desafios, tensionamentos e ensinamentos em relação às metodologias historicamente construídas e socialmente legitimadas, pois se constata o envolvimento do pesquisador e o protagonismo dos sujeitos participantes.
PROGRAMA DE INTERVENÇÃO EDUCATIVA PARA O TRATAMENTO DA OBESIDADE INFANTIL BASEADO EM VÍDEOJOGOS ATIVOS
Authors: González González Carina Soledad , Gómez del Rio Nazaret , Navarro Adelantado Vicente
Published: April 2018

A obesidade infantil é a doença crônica mais prevalente nos países desenvueltos e em desenvolvimento. Estudos recentes mostraram que as Canárias é a comunidade espanhola com a maior taxa de obesidade infantil. No entanto, esta doença é facilmente evitável se educar as crianças com hábitos saudáveis. E o desenvolvimento das TICs em geral e dos videojogos em particular representam uma oportunidade de trabalhar para uma mudança. Por isso, neste trabalho se apresenta a concepção de um programa de intervenção educativa para o tratamento da obesidade infantil. Este programa é destinado a crianças de 8 a 12 anos com obesidade e que vão pela primeira vez ao Serviço de Pediatria do Hospital Universitário de Canárias, e atualmente está sendo validado. Os resultados parciais mostram que a satisfação no âmbito do programa é alta, com destaque para o foco em jogos. Além disso, 100% das crianças acreditam que aprenderam através do programa de intervenção educativa, e que tanto a atividade física (91,7%), como uma alimentação saudável (90,9%) mudaram seus hábitos de vida.
OS SUJEITOS EM TEMPOS COMPLEXOS À LUZ/SOMBRA DA ONTOLOGIA DE EDGAR MORIN
Authors: Marques Luciana Pacheco , Jesus Alan Willian
Published: April 2018

Neste texto, situamos a questão do sujeito à luz/sombra do pensamento de Edgar Morin, que necessita de uma autoética, de uma autocrítica, de ensinar a condição humana, considerando a questão do ser e do saber no pensamento complexo, dadas as desordens e incertezas destes tempos complexos.
MESTRADOS PROFISSIONAIS: A ITINERÂNCIA DA ÁREA DE EDUCAÇÃO E OS LEGADOS DA UNIVERSIDADE DO ESTADO DA BAHIA
Authors: Hetkowski Tânia Maria , Dantas Tânia Regina
Published: April 2018

Este artigo apresenta a itinerância e os legados dos Programas de Pós-Graduação em Educação, na modalidade profissional, que são ofertados no Departamento de Educação, Campus I, da Universidade do Estado da Bahia. Objetiva, primeiramente,rememorar a criação dos Mestrados Profissionais no Brasil, a fim de destacar a sua trajetória, legitimação e consolidação em todo o território brasileiro e, posteriormente, demonstrar as principais características dos dois programas: Gestão e Tecnologias Aplicadas à Educação (GESTEC) e Educação de Jovens e Adultos (MPEJA). Do ponto de vista metodológico, este é um trabalho descritivo, com destaque para alguns dados quantitativos e qualitativos, coletados para embasá-lo, que se subsidia na legislação que ampara a criação e a implantação desses programas, que visa promover uma reflexão sobre as políticas públicas no campo da pós-graduação em educação,chamando atenção para a relevância de ofertar esses cursos, especificamente nesta modalidade, sobretudo para os professores e gestores da educação básica, principais protagonistas e demandantes destes cursos. Autores como Cevallos e Passos (2012), Ribeiro (2006), André (2001), Nóvoa (2009), Machado (2009), Haddad e Di Pierro (1999) e Flecha (1999) dialogam com as pesquisadoras na análise dos dados. Os resultados mais evidentes são decorrentes de práticas educativas inovadoras, dos trabalhos de curso realizados pelos estudantes, incremento da pesquisa educacional,dados novos e informações atualizadas sobre educação, tecnologia, gestão e Educação de Jovens e Adultos (EJA), bem como novas metodologias e artefatos tecnológicosque são impulsionados pelas investigações realizadas por discentes com a orientaçãodos docentes credenciados nos referidos programas.
ATTITUDE OF COMMON PEOPLE TOWARDS GST (GOODS AND SERVICES TAX) IN INDIA
Authors: Shukla Vimal Kishor
Published: April 2018

India is going through a lot of change right now, first demonetization attempt to curb the black money and eradicate corruption and now a few months later GST bill to make sure there should be no space for the reasons of corruption which will directly boost our Indian economy. We have written this article to make you aware of the effects and impacts of GST on various aspects of our lives. The best part about this article is that with this core information you can prepare a decent essay or speech for your speech and essay competition. Because I am pretty sure the GST is going to be the topic of discussion in every school and college too. The death of all taxes: With the unified tax regime common people said goodbye to a plethora of indirect taxes making India One Nation One Market One Tax country. Now, businesses don’t need to worry about the plethora of taxes
Preferences for Web-Based Information Material for Low Back Pain: Qualitative Interview Study on People Consulting a General Practitioner (Preprint)
Authors: Riis Allan , Hjelmager Ditte Meulengracht , Vinther Line Dausel , Rathleff Michael Skovdal , Hartvigsen Jan , Jensen Martin Bach
Published: April 2018

BACKGROUND

Information on self-management, including addressing people’s fears and concerns, are core aspects of managing patients with low back pain (LBP). Web apps with patient information may be used to extend patient-physician consultations and encourage self-management outside of the consultation room. It is, however, important to identify the end users’ needs and preferences in order to maximize acceptance.

OBJECTIVE

The aim of this study was to identify preferences for the content, design, and functionality of a Web app with evidence-based information and advice for people with LBP in Denmark.

METHODS

This is a phenomenological qualitative study. Adults who had consulted their general practitioner because of LBP within the past 14 days were included. Each participated in a semistructured interview, which was audiotaped and transcribed for text condensation. Interviews were conducted at the participant’s home by 2 interviewers. Participants also completed a questionnaire that requested information on age, gender, internet usage, interest in searching new knowledge, LBP-related function, and pain.

RESULTS

Fifteen 45-min interviews were conducted. Participants had a median age of 40 years (range 22-68 years) and reported a median disability of 7 points (range 0-18) using the 23-item Roland Morris Disability Questionnaire. Participants reported that Web-based information should be easy to find and read, easily overviewed, and not be overloaded with information. Subjects found existing Web-based information confusing, often difficult to comprehend, and not relevant for them, and they questioned the motives driving most hosting companies or organizations. The Patient Handbook, a Danish government-funded website that provides information to Danes about health, was mentioned as a trustworthy and preferred site when searching for information and advice regarding LBP.

CONCLUSIONS

This study identified important issues to consider when developing and supplementing existing general practice treatment with Web-based information and advice for patients with LBP. Development of a Web app should consider patient input, and developers should carefully address the following domains: readability, customization, design, credibility, and usability.
IMPACT OF PROLONGED REDUCED-PRESSURE CONDITION PRIOR TO PRECURSOR LABELING ON THE LABELING EFFICIENCY OF F-18 FLUOROCHOLINE SYNTHESIS
Authors: H. Hishar , H. Hanafi M. , S. Fathinul Fikri A.
Published: April 2018

Objective: The goal of this preliminary work was to observe the impact of the prolonged reduced-pressure condition prior to labeling stage on the F-18 Fluorocholine labeling yield at the end of synthesis.Methods: At this present work, the condition inside the reactor vial prior to labeling stage was manipulated. In the first technique of syntheses of F-18 Fluorocholine, the condition inside the reactor vial was set at 0 atmospheric pressure (0 atm) while in the second technique the condition inside the reactor was set at reduced-pressure (between-0.65 to-0.85 bars) with the delay time of 120 seconds. At the end of the synthesis, the impact of the prolonged reduced-pressure condition prior to precursor labeling was measured in terms of labeling yield of F-18 Fluorocholine. Results: With the second technique, the labeling yield of F-18 Fluorocholine was elevated from 9.7% (the first technique) to 24.3%.Conclusion: This preliminary work indicates that delay in a reduced-pressure condition prior to labeling step has greatly improved the labeling yield of F-18 Fluorocholine at the end of synthesis. Using this approach, the labeling yield of F-18 Fluorocholine was elevated from 7.5% to 24.3%.
EXTRACTIVE-SPECTROPHOTOMETRIC DETERMINATION OF SOME ANTIMUSCARINIC ANTAGONIST IN TABLET FORMULATIONS USING ERIOCHROME CYANINE R
Authors: El-didamony Akram M. , Saad Monuir Z. , Saleem Nora O.
Published: April 2018

Objective: To develop and validate simple, rapid and sensitive spectrophotometric method for the assay of four antimuscarinic antagonists, namely oxybutynin (OXB), solifenacin (SOL), tolterodine (TOL) and fesoterodine (FES) in bulk and pharmaceutical formulations.Methods: The proposed method is based on the reaction of the selected drugs with eriochrome cyanine R (ECR) in buffered aqueous solution at pH 1.0. The formed ion-pair complexes were extracted with dichloromethane and measured quantitatively with maximum absorption at 464 nm. All variables that affect on color intensity such as pH, buffer volume and concentration of ECR and extractive solvents were studied and optimized.Results: The calibration graphs were linear over the concentration range of 4–24, 4–32, 4–32 and 2–22 mg/ml for OXB, SOL, TOL and FES, respectively. The stoichiometry of the reaction was found to be 1:1 in all cases. Molar absorptivity values were found to be 2.043×104, 1.856×104, 1.798×104 and 2.856×104 l/mol/cm for OXB, SOL, TOL and FES, respectively. Excipients which used as an additive in commercial formulations did not interfere in the analysis.Conclusion: The developed method was successfully applied to determine OXB, SOL, TOL and FES in pharmaceutical preparations. The developed method can be used for quality control and routine analysis where time, cost effectiveness and high specificity of analytical technique are of great importance.
ACUTE POST COMPLICATIONS IN STROKE PATIENTS VISITING A TERTIARY TEACHING HOSPITAL
Authors: T. Spurthi , K. Rekha Rani , Y. Navya , D. Swathi , P. Ramesh Kumar
Published: April 2018

Objective: The study was focused on assessing the incidence of stroke and their association with types of the risk factor, with an emphasis on acute post complications and their symptomatic management for early detection.Methods: A prospective observational study was carried out on stroke patients visiting a medicine department of a tertiary hospital, Andhra Pradesh, India from August 2017 to November 2017. Patient’s demographics and lab data was collected for analysis.Results: A total of 110 patients participated in the study. Among them high incidence is males (69%), 61-80yrs (48%), with 2 risk factors (35%) among which age (67%) and hypertension (66%) were related to the high degree of prevalence. 47% of the study population were identified with one complication, among which seizures account for 38% of patients. All the complications associated with the condition were treated with drug classes, in which anti-epileptic drugs (AEDs) were the mainstay in the management of epilepsy.Conclusion: Brain edema and seizure attack were the most accountable complications identified in the study population. The early detection of these problems can improve the stroke outcomes and can reduce the mortality or disability rate.
A COMPARATIVE EVALUATION OF THE EFFICACY OF TRIPLE DRUG THERAPY WITH DUAL DRUG THERAPY IN COPD PATIENTS
Authors: Khan Pathan Amanulla , Sujala A. , Nousheen B.b. Sarah , Fatima Ayesha Farhath , Ala Hibba Tul , Reddy A.b.t. Pallavi
Published: April 2018

Objective: The present study was conducted with the objective of analyzing the efficacy of triple-drug combination therapy (formoterol, ciclesonide, tiotropium) by comparing it with double drug combination therapy (formoterol, budesonide).Methods: A prospective observational study was conducted. Sixty patients were enrolled, and divided into two groups of thirty each; one group was treated with the double-drug and the other with a triple drug combination. FEV1 and FVC pre-and post-treatment in either group were assessed spirometrically. Score ranges of 0-10, 11-20 and 21-30 were allotted to mild, moderate and severe categories and results were analyzed statistically.Results: Of the 60 patients recruited, 61-70 y olds constituted the majority (35%) of the population. Males (63.3%) were more in number compared to females (36.6%). Twenty-three of thirty-eight men smoked (60.5%); there were no female smokers. Common symptoms included cough (93.3%), dyspnoea (85%), fever (45%) and haemoptysis (15%). Hypertension accounted for 70% of patient comorbidities, followed by diabetes (60%) and cardiovascular diseases (40%). Three months after treatment with triple therapy, a significant increase in the differences of means of both FEV1 (14.27) and FVC (14.90) values was observed. Further analysis based on score ranges demonstrated that triple therapy administration markedly reduced the number of patients suffering from severe COPD.Conclusion: Our comparative analysis indicated that triple therapy was more effective in improving lung function, enhancing patients’ quality of life (evidenced from score ranges) thereby reducing mortality. While much is known about the greater effectiveness of triple over dual therapy, researchers to formulate the most effective triple therapy are in progress.
IMPLICATIONS OF MOBILE PHASE COMPOSITION AND PH ON THE CHROMATOGRAPHIC SEPARATION OF AMITRIPTYLINE AND ITS METABOLITE NORTRIPTYLINE
Authors: Buhagiar Luana Mifsud , Scorpiniti Manuel , Bartolo Nicolette Sammut , Szijj Janis Vella , Ferrito Victor , Inglott Anthony Serracino , Laferla Godfrey
Published: April 2018

Objective: Separation of tricyclic compounds sets the keystone for determining parent drug to metabolite concentration ratios and analysing impurities. The combined effects of acetonitrile composition and pH of the mobile phase on the separation of amitriptyline and nortriptyline by reversed-phase high-performance liquid chromatography (RP-HPLC) are presented.Methods: A series of RP-HPLC triplicate runs were carried out using acetonitrile and a phosphate buffer as the mobile phase and a Kinetex® C18 LC Column as the stationary phase using an Agilent 1260 Infinity Series® II liquid chromatography system with UV/visible detection. The stationary phase, column temperature, injection volume and flow rate were kept unchanged during analysis. Mobile phase composition and pH were varied to observe impact on peak shape, resolution and retention time, taking into consideration green analytical chemistry aspects.Results: Optimal chromatographic outcomes were achieved when using the mobile phase made up of 35% acetonitrile and 65% buffer at a pH of 5.6. These conditions resulted in nortriptyline and amitriptyline eluting at 4.66 min and 5.92 min respectively. Increasing the organic modifier content of the mobile phase to 40% completed separation within a run time of 4 min with comparable resolution. The 2 min gained by increasing 5% acetonitrile may not be justified due to potential implications on greening laboratory practices.Conclusion: Reversed-phase chromatography embodies a simple method for the separation of compounds that are similar in structure. Attuning the percentage of organic modifier and buffer pH provides acceptable retention times, without compromising resolution between neighbouring peaks.
Developing a Digital Archive for Symbolic Resources in Urban Environments - the Latina Project
Authors: Harland Robert , Liguori Antonia , Cole Gareth
Published: April 2018

The project described in this paper was funded to establish the foundation for a digital archival resource for researchers interested in the way people interact with urban environments through graphic communications. The research was internally funded by Loughborough University as part of its Research Challenge Programme and involved two members of academic staff and two library staff.[1] Two PhD students also participated.
The archive consists of a small number of images and will act as a proof of concept, not only for this project but also for current and future funding applications. It is hoped that an extended archive will be useful not only to visual communication researchers, but also historians, architects, town planners and others. This paper will describe the data collection process, the challenges facing the project team in data curation and data documentation, and the creation of the pilot archive.
The creation of the archive posed challenges for both the researchers and Library staff. For the researchers:

Choosing a small number of images as a discrete collection but which also demonstrated the utility of the project to other disciplinary areas;

Acquiring the necessary knowledge and skills to enable good curation and usability of the digital objects, e.g. file formats, metadata creation;

Understanding what the technical solution enabled and where compromises would have to be made.

For library staff:

Demonstrating the utility of the Data Repository;

Understanding the intellectual background to the project and the purpose of the Data Archive within the project;

Clearly explaining the purpose of metadata and documentation.

The Latina Project has demonstrated the value of a true partnership between the academic community and the professional services. All parties involved have learnt from the creation of the pilot archive and their practices have evolved. For example, it has made the researchers think more carefully about data curation questions and the professional services staff identify more closely with the research purposes for data creation. By working together so closely and sharing ideas from our different perspectives we have also identified potential technical developments which could be explored in future projects. All members of the group hope that the relationships built during this project will continue through other projects. [1] Academic staff: Drs Harland and Liguori. Library staff: Gareth Cole and Barbara Whetnall.
Problems of Computer Spectral Processing of Signals in Musical Acoustics
Authors: Ponomareva N V
Published: April 2018

Изложены проблемы компьютерной спектральной обработки сигналов в музыкальной акустике. Рассмотрены этапы преобразования музыкально-акустического сигнала. Дан анализ причин проявления проблематики спектральной обработки сигналов в музыкальной акустике на основе дискретного преобразования Фурье (Discrete Fourier Transform - DFT). Рассмотрена эффективность и результативность скользящего дискретного преобразования Фурье (Sliding Discrete Fourier Transform) в задачах компьютерной спектральной обработки сигналов в музыкальной акустике. Рассмотрены алгебраические формы параметрического дискретного преобразования Фурье (Parametric Discrete Fourier Transformation) и скользящего параметрического дискретного преобразования Фурье (Sliding Parametric Discrete Fourier Transformation). Проведен системный анализ методов и алгоритмов компьютерной спектральной обработки музыкально-акустических сигналов с целью выявления их достоинств и недостатков, выдвинута рабочая гипотеза решения порождаемой ими проблематики. Сформулированы основные задачи по решению проблем компьютерной спектральной обработки сигналов в музыкальной акустике. Приведены результаты экспериментальных исследований по выделению основного тона музыкально-акустических сигналов на основе дискретного преобразования Фурье. Проиллюстрировано на реальных музыкально-акустических сигналах, насколько повышается детализация представления спектрально-временной картины звуков музыкальных инструментов в случае перехода от скользящего дискретного преобразования Фурье к параметрическому дискретному преобразованию Фурье.
Taxonomic Model of Mathematical Competences of Undergraduate Students in a Technical University
Authors: Iskanderova A B , Bulatova E G
Published: April 2018

Современное высшее образование РФ основано на модели подготовки студентов, ориентированной на развитие его активности, способности принимать решение и нести ответственность за сделанный выбор. Обсуждается вопрос, что результаты обучения в Федеральном государственном образовательном стандарте (ФГОС) представлены в терминах компетентностного подхода, и поэтому их невозможно измерить. Отсутствие измерителей результатов подготовки студентов по дисциплине «математика» не позволяет установить соответствие подготовки будущего бакалавра заданным требования ФГОС. Представлена таксономическая модель математических компетенций студентов бакалавриата в техническом вузе, перечень которых разработан методом групповых экспертных оценок. Модель предусматривает формирование трех групп математических компетенций: базовых, методологических, креативных. Каждая группа математических компетенций представлена деятельностными и когнитивными составляющими. Иерархическая структура математических компетенций соответствует модели их формирования. Предложенный перечень математических компетенций является обобщенным. Для реализации целей диагностики степени сформированности компетенции необходимо конкретизировать их в контексте определенной темы дисциплины. Рассмотренная модель математических компетенций позволяет конкретизировать цели обучения, формулировать рекомендации для оптимального формирования системы компетенций, оптимизировать процесс обучения студентов.
The Paradigm of Continuous Education: Approaches to Essence
Authors: Volovik I V
Published: April 2018

Автор, анализируя феномен «непрерывное образование», делится размышлениями о том, что, возможно, для изучения и осознания потребностей инновационного общества необходимо дополнить педагогическую и образовательную парадигмы парадигмой непрерывного образования. Для данной парадигмы характерно то, что главную роль играет сам обучающийся со своей мотивацией познания, создающий собственные критерии, направленные на конструирование будущего в условиях нарастающей неопределенности, что способствует формированию стабильной основы в профессиональной деятельности и подготовке к изменениям жизненного процесса и рефлексии. Парадигма непрерывного образования меняет акценты с прагматических знаний на развитие общей культуры, с исторического контекста становления научного знания - на современные представления о структуре и целостном содержании системы наук. Речь может идти о необходимости перехода к совершенно новой философской концепции непрерывного образования, целью которой должна быть признана не только образованность человека, но и умение быстро адаптироваться к новой глобальной экономике. В условиях высокой социальной динамики и непрерывных изменений в социальных и профессиональных структурах задачей непрерывного образования является не только ликвидация функциональной неграмотности населения, но и решение проблем неграмотности технологической, то есть использования новых технологий по мере их появления, а также устранение транс-неграмотности - проблем с применением информации из разных источников в повседневной жизни. Проблемы создания парадигмы непрерывного образования должны стать объектом дальнейших многоплановых системных исследований интегративного междисциплинарного характера, которые в последнее время все чаще описываются через феномен трансдисциплинарности.
Regional Equity Market of Russia: Trends and Prospects
Authors: Kabirov R G
Published: April 2018

Статья посвящена анализу современного состояния регионального фондового рынка России, его тенденциям и перспективам. Рассмотрены различные точки зрения на региональный рынок ценных бумаг, его сущность и структуру, выделены критерии классификации регионального фондового рынка. Исследованы основные элементы и структура регионального рынка ценных бумаг, его специфические свойства. Особое внимание уделено тенденциям развития региональных фондовых рынков в России, их взаимодействию с национальным рынком ценных бумаг. Рассмотрены основные субъекты этого рынка: эмитенты, инвесторы, профессиональные участники, региональные регулирующие органы и саморегулируемые организации. Экономические интересы этих субъектов различны, действуют как центробежные, так и центростремительные тенденции. Противоречия, возникающие при столкновении этих тенденций, тормозят выход региональных фондовых рынков из зачаточного состояния в зрелое. Отмечена роль регионального рынка ценных бумаг как эффективного механизма движения капиталов в экономически развитые регионы. Фондовые рынки регионов способствуют аккумулированию свободных денежных средств и их перераспределению между отраслями экономики на взаимовыгодной основе путем совершения субъектами рынка операций с ценными бумагами. Анализ показал, что нерешенность проблем фондового рынка негативно сказывается на экономике региона и страны в целом и требует решения ряда задач: аккумулирование финансовых ресурсов, стимулирование инвестиционной активности населения, разнообразие форм и способов привлечения инвестиций, использование рыночных механизмов развития отраслей и регионов.