bluuebunny/crossref_metadata_2025 huggingface dataset:
HIGHER APPENDICULAR AND TRUNK FAT MASS USING BIOELECTRICAL IMPEDANCE ANALYSIS ARE RELATED TO HIGHER RESTING BLOOD PRESSURE IN OLDER ADULTS
Authors: Takagi D. , Kageyama M. , Kojima S. , Nishida Y.
Published: December 2021

Background: Little is known about how fat mass and muscle mass in different parts of the body (e.g., appendages, trunk) using bioelectrical impedance analysis influences resting blood pressure in older adults. Objective: The purpose of the study was to clarify the association between resting blood pressure and muscle mass and fat mass in older adults using bioelectrical impedance analysis. Design: A cross-sectional study. Settings: A sample living independently in the community. Participants: The subjects were older adults between the ages of 65 and 85 years (n = 100). Measurements: Systolic, diastolic and mean arterial pressure was measured using an automatic hemodynamometer, and bioelectrical impedance analysis was used to estimate muscle mass and fat mass. Results: A positive correlation was observed between total fat mass, left and right arm fat mass, trunk fat mass, and left and right leg fat mass and resting systolic, diastolic and mean arterial pressure (p < 0.05), but this was not observed with any muscle mass (p > 0.05). In a multiple regression analysis adjusted for sex, systolic, diastolic and mean arterial pressure were independently predicted by total fat mass, left and right arm fat mass, trunk fat mass, and left and right leg fat mass (p < 0.05). Conclusions: These findings suggest that total, appendicular, and trunk fat mass, measured using bioelectrical impedance analysis, could aid in detecting the factors that increase blood pressure in clinical settings and even in daily life, thereby helping in controlling blood pressure.
TWO METHODS OF ORAL DELIVERY OF RESVERATROL: A CASE STUDY
Authors: Bojanowski K. , Bojanowski R.
Published: December 2021

Background: Resveratrol is one of the most popular nutrition supplements, especially in the older population segment, yet its safety and health benefits are not fully established. This study aimed at determining bioavailability and the physiological effects of resveratrol delivered by 2 methods in a one senior patient case study. Methods: Bioavailability of resveratrol and blood chemistry parameters following the gastrointestinal and transbuccal intake were measured, respectively, by HPLC in blood and urine, and by blood chemistry analyzer. Results: The fraction of the initially administered resveratrol detected in the blood was over 15 times higher following transbuccal intake than through the gastrointestinal tract. About 36% of the ingested resveratrol was excreted in urine as 3 major metabolites, while only 11% were secreted as major metabolites following the transbuccal intake. The major metabolite in urine peaked at the same time regardless of the method of delivery. Three long-term (31 day) cycles of resveratrol supplementation by transbuccal mucoadhesive film or by ingestion did not result in any noticeable (over 5%) variation of blood chemistry, blood pressure or the overall physical condition of the patient. Conclusion: Bioavailability of resveratrol delivered through oral mucosa may be over one log higher than by swallowing, as determined by the fraction of the initial resveratrol intake in the blood and, under metabolized form, in urine. Lack of resveratrol-associated changes in blood pressure and chemistry following long term supplementation demonstrates good tolerance to high doses of resveratrol in this senior patient case study.
WHAT ARE THE GAP BETWEEN GERIATRICIANS AND ONCOLOGIST? A SURVEY OF DOCTOR AWARENESS OF MEDICAL CARE AMONG ELDERLY PATIENTS WITH CANCER IN SOUTHWEST CHINA
Authors: Wang L.-X. , Meng Z.M. , Nie S.S. , Xiang B. , Li J. , Sun Q.Q. , Qin H. , Gong Y.L. , Pan C.C. , Yi C. , Yang Y.X. , Wang S.
Published: December 2021

Objectives: Old patients with cancer are a great challenge to physicians. This study investigated the similarities and differences in the respective opinions of geriatricians and oncologists with regard to clinical practice among elderly patients with cancer in south west China. Design, Setting, Participants and Measurements: Doctors from five local public hospitals of Sichuan were surveyed with a questionnaire via face-to-face interview. The ratio of geriatricians to oncologists’ was1:1. The questionnaire addressed respondents’ demographic characteristics and was composed of 11 multiple-choice questions and a clinical scenario. Results: The respondents included 64 oncologists and geriatricians, respectively. More than forty percent participants believed that current treatments were under-treatment. «Opinion of family members» was the top one reason for under-treatment in both groups, more oncologist choice «comorbidity» as cause of insufficient treatment than geriatricians (p=0.001). Age (57.03%) was the fifth effect factor impacting on treatment decision except for physical function (81.25%), comorbidity (71.09%) and cancer itself. Physical function, comorbidity and age between 65-84, geriatrician and oncologist did have different attitude. Conclusions: The attitude to physical function and comorbidity were the main difference between geriatrician and oncologist for their clinical decisions. A workshop should be set up to optimize the treatment proceedings.
MALNOURISHED OLDER ADULTS ADMITTED TO REHABILITATION IN RURAL NEW SOUTH WALES REMAIN MALNOURISHED THROUGHOUT REHABILITATION AND ONCE DISCHARGED BACK TO THE COMMUNITY: A PROSPECTIVE COHORT STUDY
Authors: Marshall S. , Young A. , Bauer J. , Isenring E.
Published: December 2021

Objectives: Understanding the nutritional journey that older adults make from rehabilitation to home will help to target nutrition screening and intervention programs. This study aimed to determine the nutritional status, physical function and health-related quality of life amongst malnourished older adults admitted to two rural rehabilitation units and 12 weeks post-discharge to the community. Design: Observational prospective cohort study, conducted August 2013 to February 2014. Setting: Rehabilitation units in rural New South Wales, Australia. Participants: Thirty community-dwelling, malnourished older adult inpatients (mean age 79.5±7.1 years, 57% female). Intervention: Observation of usual care: basic nutrition services typical to rural rehabilitation units. Measurements: Outcome assessments were measured at rehabilitation admission, discharge and 12 weeks post-discharge, with nutrition status via the Scored Patient-Generated Subjective Global Assessment as the primary outcome measure. Secondary outcome measures included physical function (Modified Barthel Index) and health-related quality of life (Assessment of Quality of Life-6D). Results: At admission, half of the rehabilitation patients were moderately malnourished and half were severely malnourished, with the cohort becoming and remaining moderately malnourished on discharge and 12 weeks post-discharge. Only four patients (24%) were well-nourished 12 weeks post-discharge. Following discharge, there was a trend showing decline in physical function. No improvement was found in health-related quality of life following discharge. Conclusion: Malnourished older adults admitted to rural rehabilitation units with basic nutrition care are likely to be discharged with moderate malnutrition, and remain moderately malnourished in the community for at least 12 weeks. Physical function and health-related quality of life remain poor in this population. Collaboration between health services and within the multidisciplinary team is essential to identify and treat malnourished older adults, and novel approaches for inpatient and post-discharge nutrition support is needed.
DIFFERENCES BETWEEN CANADIAN AND MEDITERRANEAN DIETS: AN ASSESSMENT OF MACRONUTRIENTS IN THE DIETS OF CANADIAN OLDER ADULTS USING DATA FROM THE CANADIAN COMMUNITY HEALTH SURVEY 2.2
Authors: Culum I. , Orange J.B. , Forbes D. , Borrie M.
Published: December 2021

Introduction: The World Health Organization (WHO) recommends a diet that limits saturated fat consumption and encourages unsaturated fat consumption. A diet that is compatible with the WHO recommendations and of considerable interest to researchers interested in dementia is the Mediterranean diet (MeDi). What is known empirically at present about the MeDi and dementia is that t may have roles to play in reducing the risk factors as well as the overall risk for developing dementia. Objectives: In this cross-sectional study, we examined the macronutrient composition of the average Canadian diet (CanDi) in order to see how it may differ from the average Mediterranean diet (MeDi). Additionally, we compared how the CanDi differs between groups based on gender, age, geographical location and classification (i.e. urban vs. rural), and dementia risk. Design: The Canadian Community Health Survey (CCHS) 2.2 data were used to estimate the macronutrient composition of the CanDi for older adults (age 50+) (N = 10,503 [4,955 male, 5,548 female], mean age = 64[10.30]). Results: The average daily macronutrient intake in a CanDi was found to be 227.7 g of carbohydrates, 78.5 g of proteins, 67.8 g of fats (21.8 g of saturated fats, 27.1 g of monounsaturated fats, and 12.4 g of polyunsaturated fats), as well as 8.3 g of alcohol and have an average energy value of 1856.9 Kcal. The energy breakdown by macronutrient in a CanDi is estimated as follows: 49.2% from carbohydrates, 16.9% from proteins, and 31.1% from fats (10% saturated, 12.3% monounsaturated, and 5.7% polyunsaturated fats). On average, the respondents did not meet the daily energy requirements for their respective age group as outlined in Canada’s Food Guide. Conclusion: The macronutrient composition of the CanDi differs not only from the MeDi, but also from previous Western diet generalizations. Of particular interest is the finding that respondents identified as being “at-risk” for developing dementia consumed significantly less of each macronutrient and less food overall than those who were identified as otherwise healthy.
NUTRITIONAL RISK IN HOSPITALIZED OLDER ADULTS WITH NEOPLASMS
Authors: Braga V. , Braga de Aquino J.L. , Leandro-Merhi V.A.
Published: December 2021

Objective: To investigate nutritional risk in hospitalized older adults with neoplasms. Methods: This cross-sectional study collected the following data from 142 older patients: gender, age, length of hospital stay (LHS), death outcome, and nutritional status indicators, such as body mass index (BMI), nutritional risk screening (NRS), subjective global assessment (SGA), and energy intake. The statistical analyses included the tests chi-square, Fisher’s exact, and Mann-Whitney’s at a significance level of 5%. Results: According to the NRS, 42.25% of the patients were at nutritional risk, and according to the SGA, 40.14% of the patients were malnourished. A total of 6.34% of the patients died. Death outcome was significantly associated with gender (p=0.0408); SGA (p=0.0301); NRS (p=0.0360); and LHS (p=0.0043). Nutritional risk (NRS) was significantly associated with SGA and BMI (p<0.0001), and LHS (p=0.0199). Conclusion: Death outcome was more common in malnourished patients, patients at nutritional risk, and patients with longer LHS. Nutritional risk was associated with malnutrition (SGA), BMI, and longer LHS. Hence, early nutritional care should be provided routinely in the hospital care of hospitalized older patients.
COMPARISON OF ITALIAN AND NORWEGIAN POSTACUTE CARE SETTINGS FOR OLDER PATIENTS IN NEED OF FURTHER TREATMENT AND REHABILITATION AFTER HOSPITALIZATION
Authors: Abrahamsen J.F. , Rozzini R. , Boffelli S. , Cassinadri A. , Ranhoff A.H. , Trabucchi M.
Published: December 2021

Background/Objectives: Little is known regarding the influence of sociodemographic and clinical factors, on the short term outcomes of different postacute care (PAC) models in different countries. Design and setting: Prospective cohort study of a 19- bed Italian hospital subacute care (SAC) unit and a 19-bed Norwegian nursing home (NH) intermediate care (IC) unit, both based on Comprehensive Geriatric Assessment and similar multidisciplinary staffing. Participants: A total of 664 Italian and 961 Norwegian community-dwelling patients ≥70 years of age, in need of postacute geriatric based treatment, rehabilitation and care. The patients were admitted from acute medical, surgical and orthopaedic hospital units. Measurements: Demographic data, clinical information, comprehensive geriatric assessment (CGA), discharge destination and length of stay were recorded in an Italian and a Norwegian database and compared. Results: The Italian patients receiving hospital SAC, were more seriously affected by the acute disease and trauma, median Barthel index (BI) at admission/discharge was 40/60, compared to 75/85 in the Norwegian patients, and fewer of them were able to return to own home as compared to the Norwegian patients ( 64% vs. 82%). Although the Italian patients had a lower BI at discharge, fewer of them were transferred to nursing homes (9%), as compared to the Norwegian patients (14%), while more of them were discharged to further rehabilitation, acute hospitalization, hospice or died (27%), as compared to the Norwegian patients (4%). Of the patients discharged to own home, only 8% of the Italian compared to 71% of the Norwegian patients received nurse assisted home care. Admission BI and improvement in BI, were highly significant predictors for the ability to return home in multivariate logistic regression analysis both in the Italian and the Norwegian patients. Conclusions: Both clinical and sociodemographic factors influenced the clinical outcome of older patients receiving PAC in Italy and Norway. Such differences should be taken into account when results from different PAC models in different countries are compared. Both the Italian hospital SAC model and the Norwegian NH IC model are feasible and good alternatives, but more firm inclusion criteria may further optimize the selection of patients suitable for different PAC options.
EVALUATION OF THE RELATIVE VALIDITY OF FOOD RECORD CHARTS (FRCS) USED WITHIN THE HOSPITAL SETTING TO ESTIMATE ENERGY AND PROTEIN INTAKES
Authors: Bartkowiak L. , Jones J. , Bannerman E.
Published: December 2021

Objective: To determine the relative validity of two semi-quantitative food record charts (FRCs) to estimate patients’ energy and protein intakes. Design, setting & participants: A pilot service evaluation of twenty seven patients in adult acute care wards in an NHS hospital, Scotland UK. Measurements: Weighed plate-wastage was undertaken to measure dietary intakes of patients being monitored using FRCs on two adult acute wards. Both FRCs listed food items typically served at each meal along-with an indication of portion size on a Likert scale. All items consumed over 12 hours (three meals and two snacks) were weighed prior to provision and all left-over items were weighed once eating had terminated to determine amounts consumed. Estimated energy and protein intakes from both methods were determined and compared using 95% limits of agreement. Results: FRCs on both wards underestimated energy and protein intakes (mean bias (95% CI): Ward A, n=12; -219 (-1170, 732) kcal; -five (-50, 40) gram and Ward B, n=15; -437 (-1403, 529) kcal, -18 (-57, 21) gram). All 12 FRCs on ward A and 13 out of 15 records on ward B were incomplete due to omissions of whole meals or omissions of particular foods and drinks throughout the day. Details of ‘portion eaten’ were frequently omitted from the completed FRCs on both wards. Discrepancies existed between food items documented on FRCs to those observed and weighed. Conclusions: Further development of FRCs and training of staff is needed to ensure appropriate completion and thus accurate estimation of patients’ intakes to better inform nutritional care.
CITICOLINE EFFICIENCY ON COGNITIVE FUNCTION: A SYSTEMATIC REVIEW
Authors: Cano-Cuenca N. , Solís-García del Pozo J. , Jordán J.
Published: December 2021

Background: Citicoline is considered an ingredient in particular foods in the USA and is available in pharmaceutical form in Europe and Japan. It has been postulated to render positive effects on the nervous system, either by increasing levels of neurotransmitters, or by affording neuroprotection. Methods: Several clinical trials have shown the efficacy and safety of this biomolecule in several neurodegenerative diseases and in acute ischemic stroke. Here, we have performed a systematic review to validate the effect of citicoline on MMSE, memory, attention, and basic activity of daily living. In electronic database searches, we found 14 randomized clinical trials reporting citicoline effects on cognitive function. Findings: A positive effect of citicoline on MMSE in acute ischemic stroke was found, which was not evidenced for Alzheimer disease or vascular dementia. On activities of daily living, citicoline failed to exert beneficial effects in patients with acute ischemic stroke or progressive cognitive impairment. Conclusions: Given the present data there is no evidence that supports advising patients with cognitive alterations to take chronic citicoline supplements.
Metastatic Cancer of Apparent Colon Origin With No Intraluminal Cancer After Resection of Colorectal Lateral Spreading Lesions
Authors: Lee Christopher J. , Vemulapalli Krishna C. , Lin Jingmei , Rex Douglas K.
Published: December 2021

We report a case of metastatic adenocarcinoma to the liver that presented 5 months after piecemeal endoscopic mucosal resection of 3 benign lateral spreading adenomas in the cecum. The pathologic features of the metastatic cancer indicated a probable colonic origin. However, when the cancer was identified, there was no endoscopic evidence of recurrent polyp or another primary lesion in the colon.
Disseminated Histoplasmosis Mimicking Acute Liver Failure in a Patient Treated With a Tumor Necrosis Factor Inhibitor
Authors: Saxena Damini , Lange Andrew , Daves Seanna R. , Punzalan Carmi S.
Published: December 2021

Disseminated histoplasmosis (DH) is typically seen in patients with organ transplantation or human immunodeficiency virus and rarely presents with acute liver failure. Tumor necrosis factor inhibitors may be immunosuppressive but unlikely to result in DH. A 70-year-old woman with a history of psoriatic arthritis on infliximab presented with altered mental status, fevers, and severe liver injury. She was found to have DH, which resolved on antifungal agents. Because the use of tumor necrosis factor inhibitors has increased, providers should consider this uncommon infection in patients who present with cryptogenic severe liver injury.
Anti-diabetic effects of aqueous extract of Dendropanax morbifera Lev. leaves in streptozotocin-induced diabetic Sprague-Dawley rats
Authors: Kim Min-Jae , Kang Ye-Jin , Lee Dong-Eon , Kim Suk , Lim Se-Hun , Lee Hu-Jang
Published: December 2021

This study examined the anti-diabetic effects of aqueous extracts of Dendropanax morbifera leaves (DMWEs) in streptozotocin-induced diabetic Sprague-Dawley (SD) rats. Thirty male SD rats (body weight [BW], 250.4 ± 19.7 g) were divided into the following six groups: normal control rats (NC), diabetic control rats (DC), diabetic rats treated with metformin HCl 100 mg/kg BW (DT), diabetic rats treated with DMWEs 50 mg/kg BW (DM-50), diabetic rats treated with DMWEs 100 mg/kg BW (DM-100), and diabetic rats treated with DMWEs 200 mg/kg BW (DM-200). From two weeks of administration of DMWEs, the BW of all groups treated with DMWEs increased significantly compared to DC (p < 0.05). At four weeks after treatment, the blood glucose levels in DT, DM-100, and DM-200 decreased below 200 mg/dL, while the glycated hemoglobin concentrations in all groups administered DMWEs were similar to those of NC and DT. Regarding the blood biochemical parameters, the levels of aspartate transaminase, alanine transaminase, blood urea nitrogen, and creatinine in DM-100 and DM-200 were similar to those in NC and DT. Overall, these results highlight the effectiveness of DM-100 in the treatment of diabetes.
APPLICATION OF OPTIMIZATION OF SPECIFIED PARAMETERS OF THE ACCIDENT-RESISTANT FUEL SYSTEM OF THE HELICOPTER IN SIMINTECH SOFTWARE PACKAGE
Authors: Smagin D. I. , Napreenko K. S. , Savel’ev R. S. , Grachev S. V.
Published: December 2021

The process of creating an accident-resistant fuel system (AFS) of a helicopter using mathematical modeling is considered. Possibility of applying optimization algorithms in mathematical modeling of parameters of units of accident-resistant fuel system of helicopter in domestic software complex SimInTech is studied. An approach to solving the problem of optimizing given parameters, both in theory and in practice, is described. Results of the simplest optimization of AFS parameters for nominal operation mode are covered, examples of algorithms for selection of unit parameters are shown. This method of researching the system will allow, with a high degree of accuracy, to determine the necessary parameters at the design stage of the system. It is worth noting that the functionality of the developed dynamic mathematical model in the SimInTech software package is sufficient to perform tasks not only of the conceptual design stage, but also of the subsequent stages of the AFS life cycle.
MATHEMATICAL MODEL AND AREA OF EXISTENCE OF THE FAMILY CRANKS AND MOBILE MECHANISMS WITH THE MAXIMUM TRANSMISSION ANGLE
Authors: Sereda N. A.
Published: December 2021

The article examines crank-rocker mechanisms. Such mechanisms are used in transport and technological machines. The article is devoted to the search for a new family of crank-rocker mechanisms. A mathematical model of a new family of crank-rocker mechanisms is obtained. In this family, the maximum transmission angle reaches 90 when the crank angle is 75. Thus, the new family of crank-rocker mechanisms differs from the known families by the position of the mechanism in which the maximum of the transmission angle function takes place. It is shown that, with a certain ratio of link lengths, the new family corresponds to the known families KKM-5 and KKM-7. The area of existence of a new family of crank-rocker mechanisms is established. This area is bounded by the arc of the circle of the unit radius and the curve. The mentioned curve is based on a joint solution of a mathematical model of a new family of mechanisms and the famous Kolchin straight line. The dependence for the minimum transmission angle is obtained. A formula for determining the angle of the rocker arm span is proposed. A graphical interpretation of the mentioned dependencies and formulas is constructed. The scope of existence of a new family of crank-rocker mechanisms and graphical interpretations are used in determining the geometric parameters of mechanisms. These mechanisms are part of a new family of mechanisms.
INVESTIGATION OF THE MATERIAL QUALITY PARAMETERS OF THE SURFACE LAYER OF THE PART WHEN PROCESSING WITH ELBOROV GRINDING WHEELS ON A GALVANIC BUNDLE
Authors: Golovanov D. S. , Bezyazychzny V. F. , Kiselev E. V.
Published: December 2021

The article considers the results of research on the influence of technological conditions when processing circles made of cubic boron nitride on the main quality parameters of the surface layer of parts made of a material with a high Nickel content. The advantages of the deep grinding method for processing iron-Nickel alloys with grinding wheels made of cubic boron nitride on a galvanic bond are presented.
GENERAL METHOD FOR CALCULATING BUTT AND ANGLE WELDS FOR STRENGTH
Authors: Vavilov Yu. N. , Skobeleva I. Yu. , Shirshova I. A.
Published: December 2021

The existing methods for calculating butt and fillet welds are private, developed for specific design solutions that do not take into account the variety of weld shapes and the variety of combinations of forces and moments. The article provides a general method for calculating butt and fillet welds for strength, based on the calculation method for nominal stresses, adopted in the strength of materials. This technique was used without any changes for the calculation of butt welds, since the weld is an extension of the part. The calculation of fillet welds is based on two assumptions, on the basis of which a calculation scheme has been developed, which makes it possible to use the calculation method for rated stresses. The article proposes two design schemes, considers the calculation procedure and derives two generalized strength conditions for the verification calculation of butt and fillet welds.
SYSTEM ANALYSIS AND SYNTHESIS OF GAS-TURBINE STAGES AERODYNAMIC PERFORMANCE
Authors: Bezjazychnyj V. F. , Vinogradov K. A. , Vinogradova O. V. , Fadeev V. A.
Published: December 2021

A method for system improvement of gas turbine flow-passage at the preliminary design stage is proposed. The results of 1D aerodynamic calculation is the reference information. Based on the obtained structural parametrical models a wide range of analysis, synthesis and optimization problems can be solved, as well as uncertainty quantification problem for turbine blade permissible manufacture tolerances in batch production.
HOMOMORPHIC OPERATIONS WITHIN IDEAL LATTICE BASED ENCRYPTION SYSTEMS
Authors: Kadykov V. Yu. , Levina A. B.
Published: December 2021

By 2009 the first system of fully homomorphic encryption had been constructed, and it was thought-provoking for many future works based on it. Instead of legacy encryption systems which depend on sharing a key (public or private) among endpoints involved in exchanging en encrypted message the fully homomorphic encryption can keep service without depending on shared keys and does not necessarily need to access the content. Such property allows any third party to operate on the encrypted data without decrypting it in advance. In this work, the possibility of using the ideal lattices for the construction of homomorphic operations is researched with a detailed level of math.The paper represents the analysis method based on the primitive of a union of ideals in lattice space. A segregated analysis between homomorphic and security properties is the advantage of this method. The work will be based on the analysis of generalized operations over ciphertext using the concept of the base reducing element which shares all about the method above. It will be shown how some non-homomorphic encryption systems can be supplemented by homomorphic operations which invoke different parameters choosing. Thus such systems can be decomposed from ciphertext structure to decryption process which will be affected by separately analyzed base reduction elements. Distinct from the encryption scheme the underlying math can be used to analyze only the homomorphic part, particularly under some simplifications. The building of such ideal-based ciphertext is laying on the assumption that ideals can be extracted further. It will be shown that the “remainder theorem” can be one of the principal ways to do this providing a simple estimate of an upper bound security strength of ciphertext structure.
METHOD FOR SPLITTING THE FEASIBLE REGION TO INCREASE THE VARIABILITY OF CONTINUOUS OPTIMIZATION TEST PROBLEMS
Authors: Matrenin P. V.
Published: December 2021

The solution of optimization problems is essential for the design and control of technical systems. The optimization problem arising in practice has a high dimension, nonlinear criteria, and constraints. There are a lot of continuous optimization tasks for testing and research of optimization algorithms performance. These tasks have a convex range of acceptable values limited to a specified range for each parameter. The problem of generating test multidimensional continuous optimization tasks with nonlinear constraints and splitting the feasible region is considered. A method was proposed for splitting the feasible region by separate domains using the multidimensional grid of forbidden solutions. As a result, the problem acquires properties closer to optimizing technical systems with complex constraints. The method allows creating an unlimited number of test optimization problems, which can be used to research and develop optimization algorithms. The method is simple to implement, and the impact on the computational complexity of tasks is insignificant. Research has been carried out on four widely used continuous single-objective optimization test functions, with the Genetic algorithm and the Particle Swarm Optimization algorithm. It is shown that the proposed method has an influence on the process of solving multidimensional continuous optimization problems by population algorithms and on the dependence of the accuracy of the algorithm on its heuristic coefficients.
RECOGNITION OF HUMAN ACTIONS IN VIDEO SEQUENCES USING THE LSTM NETWORK
Authors: Teplyakova A. R. , Starkov S. O.
Published: December 2021

The development of computer vision and the wide applicability of its applied components determine the relevance of research in this field of science. One of the most interesting tasks of computer vision is to monitor the behavior of people, which includes the analysis of their actions and carried out for various purposes. Examples of use are systems for monitoring compliance with safety regulations and the wearing of personal protective equipment by workers in factories, systems such as “smart home”, which track actions, systems for monitoring the condition of people in medical or social institutions, home systems for monitoring the condition of the elderly, which are able to notify relatives in cases of emergency situations. There is no comprehensive program that can solve the described problem and its variations, regardless of the scope of application. Therefore, the development of its prototype, which is a module that solves the human action recognition problem in the video, is an important problem. The article describes the creation of a software module that solves the human action recognition problem in a video. An overview of existing data sets suitable for training a neural network is provided, and data collection and processing for a custom dataset for actions of four different classes is described. The key features of the stages of creating, training and testing a neural network with the LSTM (Long Short-Term Memory) architecture, as well as options for its practical application, are described below. The developed module is quite flexible, there is a possibility to increase the number of classes of recognized actions depending on the scope of its application, as well as the possibility of integration with other modules for monitoring the behavior of people who have a similar device.
ENSEMBLE MODELS FOR INTELLIGENT ANALYSIS OF SOCIOLOGICAL DATA
Authors: Podvesovskii A. G. , Karpenko E. V. , Lagerev D. G. , Baburin A. N.
Published: December 2021

The paper investigates an approach to sociological information processing based on the use of intelligent data analysis methods applied to the task of processing the results of a questionnaire survey. The advantages of intelligent analysis of sociological data in comparison with traditional statistical processing are discussed, as well as the implementation features and applicability limits of various intelligent data analysis methods in solving problems of association, clustering and classification. Structure and features of representation of respondents’ survey data are considered, the appropriateness is substantiated and the advantages of their processing based on the combination of various methods of intelligent analysis within an ensemble of models are discussed. A structure of an ensemble of models is proposed based on the combination and joint use of association rules, clustering algorithms and decision trees, which makes it possible to jointly process numerical and categorical data contained in the respondent’s answers to the questionnaire and also to interpret the results of data clustering. The paper describes the results of using the constructed ensemble of models for processing and analyzing the data of a sociological survey conducted as part of the annual project for monitoring the drug abuse situation in the Bryansk region in 2013 – 2018. The use of an ensemble of intelligent data analysis models for processing the results of a sociological survey not only makes it possible to detect patterns in them that cannot be otherwise detected by traditional methods of statistical processing, but also contributes to an increase in the reliability, completeness and coherence of the analysis results, due to which the analyst creates a holistic systemic picture of the studied social phenomenon or process.
TECHNOLOGY FOR THE DEVELOPMENT OF SOFTWARE ALGORITHMS FOR OPTOELECTRONIC MONITORING SYSTEMS FOR REMOTE OBJECTS
Authors: Makhov V. E. , Petrushenko V. M. , Emel'yanov A. V. , Shirobokov V. V. , Potapov A. I.
Published: December 2021

The issues of constructing algorithms for obtaining coordinate and non-coordinate information used to solve the problem of multiplexing images obtained from several optoelectronic systems are considered. A unique mathematical method for finding the corresponding points in images, based on algorithms for continuous wavelet transform of the brightness structure of an image, is proposed. The technology of development of algorithms intended for multi-position optoelectronic systems for monitoring remote objects based on software from National Instruments is considered. A technique for constructing software for obtaining information is proposed, which ensures high accuracy in determining the coordinates of the corresponding fragments in images. It is shown that the parallel use of several methods makes it possible to assess the reliability of the information obtained under conditions of changing observation parameters. The use of several methods makes it possible to assess the reliability of the information obtained under conditions of changing observation parameters. Computational experiments have confirmed that a more accurate search for image alignment regions is provided by the double wavelet transform method by increasing the number of extrema of the curves of the continuous wavelet transform coefficients, expanding the area from localization and additional filtering. An example of the practical implementation of the developed algorithms in a two-channel optoelectronic system is presented.
Pytania o życie ludzkie i znaczenie Ewangelii życia Jana Pawła II
Authors: Brusiło Jerzy
Published: December 2021

Na pytania o fenomen (osobliwość) życia w ogóle i znaczenie, sens życia ludzkiego nauki przyrodnicze nie znajdują wystarczającej odpowiedzi. Czy z punktu widzenia człowieka-obserwatora życia z zewnątrz lub świadomego uczestnika życia, można pomóc w tych pytaniach? Co ma do powiedzenia w tych kwestiach teologia i antropologia teologiczna, zwłaszcza w kontekście stworzenia i odkupienia osoby ludzkiej?

W poszukiwaniu znaczenia życia ludzkiego i odpowiedzi na pytania o życie w ogóle ważną, adekwatną i uniwersalną odpowiedź formułuje koncepcja Ewangelii życia Karola Wojtyły – Jana Pawła II. Istotną treść tej koncepcji zawiera encyklika Papieża Jana Pawła II, pod tym samym tytułem, Evangelium vitae (Ewangelia życia). Wykład encykliki o życiu pochodzącym od Boga, danym człowiekowi od Boga i zmierzającym do życia w Bogu ukazuje prawdziwy sens życia ludzkiego.

 W przejściu z biologii i metafizyki życia do duchowych cech Ewangelii (Dobrej nowiny) życia ludzkiego, które jest niepowtarzalne, wyjątkowe, nienaruszalne, niezwykłe, Jan Paweł II pozwala również na odkrycie znaczenia życia każdej istoty, każdego gatunku i formy życia na Ziemi. Kwestie te są również obecne we wspomnianej już encyklice.
Rodzina miejscem afirmacji życia i spełnienia człowieka w świetle nauczania Papieża Jana Pawła II
Authors: Ozorowski Mieczysław
Published: December 2021

Dwadzieścia pięć lat po encyklice Jana Pawła II Evangelium vitae  stoimy nadal przed poważnymi wyzwaniami związanymi z afirmacją ludzkiego życia. Rodzina jest naturalnym miejscem, gdzie życie się zaczyna, rozwija i kończy. Jest ona naturalnym „sanktuarium życia”. Kościół w tradycyjny sposób przypomina o szacunku do ludzkiego życia, które jest największym darem Bożym. Współcześni papieże  upominają się w swoim nauczaniu o ochronę życia od poczęcia do naturalnej śmierci. Kościół zachęca do pracy wychowawczej, która pozwala stawać się coraz bardziej człowiekiem, zachować szacunek do życia i nawiązywać prawidłowe relacje międzyosobowe. Najpiękniejszym wymiarem afirmacji życia jest modlitwa dziękczynna.
A highly accurate delta check method using deep learning for detection of sample mix-up in the clinical laboratory
Authors: Zhou Rui , Liang Yu-fang , Cheng Hua-Li , Wang Wei , Huang Da-wei , Wang Zhe , Feng Xiang , Han Ze-wen , Song Biao , Padoan Andrea , Plebani Mario , Wang Qing-tao
Published: December 2021

Objectives

Delta check (DC) is widely used for detecting sample mix-up. Owing to the inadequate error detection and high false-positive rate, the implementation of DC in real-world settings is labor-intensive and rarely capable of absolute detection of sample mix-ups. The aim of the study was to develop a highly accurate DC method based on designed deep learning to detect sample mix-up.

Methods

A total of 22 routine hematology test items were adopted for the study. The hematology test results, collected from two hospital laboratories, were independently divided into training, validation, and test sets. By selecting six mainstream algorithms, the Deep Belief Network (DBN) was able to learn error-free and artificially (intentionally) mixed sample results. The model’s analytical performance was evaluated using training and test sets. The model’s clinical validity was evaluated by comparing it with three well-recognized statistical methods.

Results

When the accuracy of our model in the training set reached 0.931 at the 22nd epoch, the corresponding accuracy in the validation set was equal to 0.922. The loss values for the training and validation sets showed a similar (change) trend over time. The accuracy in the test set was 0.931 and the area under the receiver operating characteristic curve was 0.977. DBN demonstrated better performance than the three comparator statistical methods. The accuracy of DBN and revised weighted delta check (RwCDI) was 0.931 and 0.909, respectively. DBN performed significantly better than RCV and EDC. Of all test items, the absolute difference of DC yielded higher accuracy than the relative difference for all methods.

Conclusions

The findings indicate that input of a group of hematology test items provides more comprehensive information for the accurate detection of sample mix-up by machine learning (ML) when compared with a single test item input method. The DC method based on DBN demonstrated highly effective sample mix-up identification performance in real-world clinical settings.
A simple theoretical, quantitative approach to help understand the titration of weak acids and bases
Authors: Arocena Miguel
Published: December 2021

What happens at the very beginning of the titration of a weak acid or base is a question sometimes asked by undergraduate students when introduced to the concept of buffer solution. To attempt to answer this question, a simple quantitative approach is developed, which also allows explaining more general properties of the weak acid or weak base titration process, while serving as well as an introduction to the theoretical, quantitative treatment of this subject. Using this approach, it can be shown that, at the beginning of the titration, the reaction between a weak acid (base) and a strong base (acid) does not occur on a one to one ratio when very small amounts of the strong base (acid) are added.
Spatiotemporal evolution of ecological environment quality in arid areas based on the remote sensing ecological distance index: A case study of Yuyang district in Yulin city, China
Authors: Yang Liangyan , Shi Lei , Wei Jing , Wang Yating
Published: December 2021

The ecological environment in arid areas of Northwest China has undergone considerable changes under the combined effects of climate change and human factors. Therefore, exploring the spatial and temporal evolution of the ecological environment quality is of great significance for the protection and management of the ecological environment in arid areas of Northwest China. This study adopted Yuyang district as the study area. Landsat Thematic Mapper/Operational Land Imager images from 1993 to 2018 were selected as the data source for the retrieval of important surface indicators and the construction of the remote sensing distance ecological index. The spatial distribution, trend, and grade classification of the ecological environment quality were monitored and analyzed. The results showed that (1) the ecological environment quality of Yuyang district from 1993 to 2018 showed an overall upward trend, mainly manifested as a sharp decline in the area of poor ecological environment from 84.81 to 53.36%. (2) The spatiotemporal changes in the ecological environment quality showed a downward trend in the central urban area and an upward trend in the noncentral urban area. (3) In general, rainfall and temperature had limited impact on the ecological environment quality. Urbanization seriously affected the local ecological environment quality and the implementation of the ecological restoration policies, regulations, and measures were the main drivers of the improvement to the ecological environment quality in other surrounding areas.
Inference of genetic regulatory networks with regulatory hubs using vector autoregressions and automatic relevance determination with model selections
Authors: Chen Chi-Kan
Published: December 2021

The inference of genetic regulatory networks (GRNs) reveals how genes interact with each other. A few genes can regulate many genes as targets to control cell functions. We present new methods based on the order-1 vector autoregression (VAR1) for inferring GRNs from gene expression time series. The methods use the automatic relevance determination (ARD) to incorporate the regulatory hub structure into the estimation of VAR1 in a Bayesian framework. Several sparse approximation schemes are applied to the estimated regression weights or VAR1 model to generate the sparse weighted adjacency matrices representing the inferred GRNs. We apply the proposed and several widespread reference methods to infer GRNs with up to 100 genes using simulated, DREAM4 in silico and experimental E. coli gene expression time series. We show that the proposed methods are efficient on simulated hub GRNs and scale-free GRNs using short time series simulated by VAR1s and outperform reference methods on small-scale DREAM4 in silico GRNs and E. coli GRNs. They can utilize the known major regulatory hubs to improve the performance on larger DREAM4 in silico GRNs and E. coli GRNs. The impact of nonlinear time series data on the performance of proposed methods is discussed.
Data Aggregation Algorithm of Sensor Network Nodes for Health Monitoring Based on Fuzzy Clustering
Authors: Liang Shujun , Cheng Jing , Zhang Jianwei
Published: December 2021

Wireless human body sensor networks are widely used, but because of hardware and environmental constraints, their nodes have problems such as unsustainable energy and weak computing capabilities. To further improve the efficiency of data aggregation for health monitoring, a fuzzy clustering based data aggregation algorithm is presented. Based on the fuzzy clustering algorithm of distributed wireless sensors, this work analyzes the processing mechanism of distributed data and introduces an optimal weighted weighting algorithm, thereby obtaining the optimal weight distribution coefficient of each sensor, results of node variance evaluation, and corresponding data aggregation through distributed data processing. The proposed algorithm is of great significance to improve the accuracy of data collection and reduce the overall energy consumption of the network.
Doris adrianae sp. nov. (Heterobranchia; Nudibranchia; Doridina) from the Galician coasts (NW Iberian Peninsula).
Authors: Urgorri Carrasco Victoriano , Pérez Se´ñarís Marcos , Díaz Agras Guillermo , Can´dás Romero María , Gómez Rodríguez Carola
Published: December 2021

Abstract

A new species of dorid nudibranch, Doris adrianae sp. nov. is described, from the Ría de Ferrol (NW Iberian Peninsula) on rocky bottoms, between 11 and 20 m deep, where the sponge Polymastia boletiformis (Lamarck, 1815) on which it feeds is common. The new species is oval-shaped and yellow to yellow-orange in colour, with the back covered by rounded tubercles of various sizes, reinforced by tegumentary spicules. It is characterised by numerous integumentary and fusiform calcareous spicules, mainly grouped in multispicular bundles that give it a complex and very dense skeletal structure, giving the animal great consistency without losing flexibility. In addition, it differs from other known species of the genus Doris Linnaeus, 1758 by various external and internal characters, mainly by the colouring and tubercles of the body, characters of the radula and of the digestive and reproductive systems. Doris adrianae sp. nov. also presents a marked genetic distance in the barcode fragment (cox1-5') with other species of the genus Doris.
Direct and inverse theorems on the approximation of almost periodic functions in Besicovitch-Stepanets spaces
Authors: Serdyuk A.S. , Shidlich A.L.
Published: December 2021

Direct and inverse approximation theorems are proved in the Besicovitch-Stepanets spaces $B{\mathcal S}^{p}$ of almost periodic functions in terms of the best approximations of functions and their generalized moduli of smoothness.
Full Text Search Setup on a Website
Authors:   V. O. Sukhomlynsky Mykolaiv National University, Khodiakova Halyna V. , Khodiakova Nataliia V. ,   V. O. Sukhomlynsky Mykolaiv National University, Pozdeev Valery A. ,   V. O. Sukhomlynsky Mykolaiv National University
Published: December 2021

ntroduction. When implementing the search for text fragments on the site, approaches are used that are different in complexity and performance. There is also a sequence of related tasks: choosing a text indexing option, sending a text for indexing, selecting texts for indexing specifically from the CMS database, choosing a search engine, and others. These approaches do not always provide satisfactory search results. Purpose. The purpose of the article is to the description of existing solutions for full-text search on a website, their advantages, and disadvantages. Development of a full-text search algorithm using the Elasticsearch system. Methods. Analysis of approaches to the implementation of full-text search on a website, varying in complexity and performance. Identification of flaws and vulnerabilities in more primitive approaches and the development of more advanced and complex algorithms that eliminate the identified deficiencies. Step-by-step implementation of full-text search using third-party systems. Results. A method for implementing full-text search using Elasticsearch is described. The advantage of the new approach is the asynchronous sending of the page content and its address to a specific service responsible for communication with Elasticsearch. This allows you not to block the normal work with the CMS and not depend on the availability of the indexing service. The approach described in the article is flexible and adaptable for various website architectures. Asynchronous processing of indexing requests ensures high query execution speed and system fault tolerance. Conclusions. The article discusses various approaches to implementing full-text search on a website, their advantages and disadvantages. Based on the analysis, a more flexible and universal approach to the implementation of a full-text search system has been developed. A solution is proposed with step-by-step implementation and setup of advanced full-text search using Elasticsearch.