bluuebunny/crossref_metadata_2025 huggingface dataset:
«Industry 4.0»: a new look at the management of economic security at the meso-level
Authors:   Market Economy Institute of RAS, Romanova Julia А. , Tamakchi Andrey S. ,   Market Economy Institute of RAS
Published: February 2021

Предмет/тема. Современный мир представляет собой принципиально новую архитектуру социально-экономической реальности, где сочетаются виртуальный и реальный миры с множеством нелинейных взаимодействий. Как никогда раньше индивид близок к партнерскому диалогу с машиной, вещи в виртуальном мире получают физическое воплощение с помощью интернета вещей. Однако любая точка невозврата развития социально-экономической системы имеет множество слабо контролируемых, а в отдельных случаях – вообще не-предсказуемых эффектов-вспышек, что обуславливает актуальность вопроса пересмотра парадигм безопасности на всех уровнях управления социумом, и особенно – на уровне инфраструктурных объектов мезоуровня – коммуникаций всех групп стейкхолдеров. Цели/задачи. Целью статьи являются вопросы необходимости развития гибкой цифровой системы управления экономической безопасностью на мезоуровне в условиях Индустрии 4.0. Методология. При рассмотрении источников авторы использовали исследования 2019-2020 гг., посвященные анализу Индустрии 4.0 и современным взглядам на управление экономической безопасностью на мезоуровне. Результаты. В рамках исследования для понимания проблемы экономической безопасности стейкхолдеров мезоуровня, которая генерируется парадигмой Индустрии 4.0, рассмотрены ее ключевые характеристики и определены потенциальные точки вызовов и угроз для социума и регуляторных институтов. Проанализированы основные бизнес-модели обеспечения экономической безопасности, применяемые на мезо-уровне в мировой практике. На примере банковской экосистемы ПАО «Сбербанк» – «Банк без границ» рассмотрены возможности и угрозы для бизнеса на мезоуровне. Основываясь на анализе структуры экосистемы «Сбербанк без границ», был выявлен набор критически важных инфраструктурных и транзакционных рисков, т.к. включение в орбиту влияния экосистемы самостоятельных рыночных агентов с собственным видением развития бизнеса необратимо приводит к возникновению противоречий при разработке стратегии развития. Для разрешения возможных конфликтов между стейкхолдерами Управляющего партнера и потенциальных партнёров исследуемой бизнес-модели предложено внедрить организационные и финансово-экономические ограничения для сторон. Выводы/значимость. В ходе исследования сделан вывод, что в условиях перехода к Индустрии 4.0 для минимизации возникающих угроз на мезо-уровне необходима цифровизация и автоматизация бизнес-процессов на всех уровнях организации производства с целью формирования цифровой экосистемы управления. Практическое значение. Выводы, полученные в ходе исследования, могут использоваться органами государственной власти и руководителями субъектов хозяйствования различных форм собственности для совершенствования системы управления экономической безопасностью на мезо-уровне.
Maqasid Al-Quran Approach Towards Understanding Jihadism and De-Radicalization
Authors: Tazul Islam
Published: February 2021

Jihad itself is not an objective in Islam. Yet, it is a means for various objectives like distinction between truth and false, gaining Allah's satisfaction, self-defence and repelling aggression. However, violent jihadism has become a source of extremism and radicalization. This research aims to dissolve the controversy aroused about implementations of jihad in contemporary era by confining its objectives. The use of Jihad, its usage and types may be determined based on its objectives. This research is qualitative in nature as it focuses only on library data. However, to explore a maqasid al-Quran perspective, books of tafsir will be used for the relevant issues. It comes out with a framework to understand jihadism and radicalization based on maqasid al-Quran.
أقوال الإمام المباركفوري التفسيرية في كتابه الرحيق المختوم جمعا ودراسة
Authors: Adnan Moh’d Abdullah Shalash  , Ragab Shehatah Mahmoud Moh’d
Published: February 2021

This study deals with the explanatory words of Imam Mubarakfuri in his book al-Rahiq al-Makhtum collection and study, and this research aims to collect the words of Mubarak's interpretation in his book Nectar Sealed and study by reference to the statements of interpreters, where the importance of the research is to add research from the interpretation of research in the books of the Prophet in this study. The researcher had followed the inductive and descriptive analytical approach, and the results of the study showed that Mubarak was able to support the historical events and the prophetic biography of the Holy Quran.
عوامل تكوين الحافظ ابن حجر العسقلاني العلمية
Authors: Shumsudin Yabi
Published: February 2021

Al-Hafiz Ibn Hajar Al-Asqalani is considered to be one of the most famous scholars of hadith in his time and the time after him. He has many compilations in hadith sciences which comprise different topics. He has a unique approach when dealing with the Hadith of Rasulullah SAW, with hadith sciences, and generally with Muslims. This research deals with the factors that have developed his character and intellect. His method was through reading and researching all of the related topics which subsequently had made his compilations to be placed at a prestigious level, and made him distinctive from his peers. He is brilliant, knowledgeable, has a photographic memory, and has spent his life in seeking knowledge, devoted to scholars and their classes, obtaining knowledge, and has benefitted from prominent scholars of his time; in which Allah SWT had prepared him for the Islamic sciences. Notably, Al-Hafiz Ibn Hajar had lived in the era of the Mamluk state, when the Islamic sciences had reached its summit and flourished, and many scholars were produced.
Report on Recent Advances in Treatment Options through Vitamins
Authors: Iqbal Saima , Gul Somia
Published: February 2021

Vitamins are the essential dietary components that are required in trace amounts by our body for the proper functioning of its biochemical processes and to prevent the deficiency diseases. The case of an infant having epileptic seizures at birth is discussed, which was found to be pyridoxine (vitamin B6) - dependent. It has been discovered through recent researches that vitamin K is involved in the immunology, atherosclerosis, inflammation and bone mineralization. Vitamin C is found to act as an anti-tumor agent when used intravenously in high doses. Recent researches have led us to understand that vitamins have a broader spectrum of functions than they are anticipated to have in our body and can be used to treat much more diseases when used alone, in combination or via different routes or in different concentrations or doses.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.234-240
Ethical issues in Kidney Transplantation and “An” Islamic perspective
Authors: Rathor Mohammad Yousuf , Shah Azarisman SM , Rozi Nur Raziana Bt , Draman Che Rosle , Syahril Wan Ahmad
Published: February 2021

Kidney transplantation (KT) is currently the most realistic treatment option for patients with end-stage renal disease (ESRD) as it enables them to live longer and provides better quality of life post-transplantation. Before the 1960s, all these patients would die as there was no treatment available. It is the commonest solid organ transplantation carried out in the world at the moment. Organs are harvested from living or cadaveric donors, with living kidney donor organs generally functioning better and for longer periods of time compared to the latter. Issues surrounding organ transplantation in general and kidney transplantation in particular, are fraught with ethical dilemmas due to the shortage of organs, the logistics behind the acquisition of organs, use of living donors including minors and the black market that has sprouted thereof. Entwined in this quagmire are the legal, social and psychological consequences for the individuals involved and the society at large. It is further compounded by religious concerns, which have a significant influence on the society’s acceptance of the practice of organ donation. The practice of organ transplantation is generally accepted by most Islamic scholars as it is concordant to the objectives of Islamic Law (maqasid al Sharī’ah) which prioritize the preservation of human life. However, resistances do arise from some jurists and even physicians of the same Islamic faith despite a fatwas decreeing that organ and tissue transplantations are permissible in Islam under certain conditions. The take-up of organ-donation is still largely poor especially among Muslims. This article therefore hopes to explore the various moral and ethical issues surrounding KT as well as the Islamic viewpoints emanating from it. We hope that this knowledge and understanding will benefit both health-care personnel and the public in general.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.241-249
Being attendant at pediatric clinics can increase bacterial contamination risk on hands?
Authors: Nemut Tijen , Dede Cemile , Menekse Dilek , Cinar Nursan , Peksen Sultan
Published: February 2021

Objective: The aim of this study was to examine the bacterial growth of the attendants’ hands and to determine the difference between the hospitalized and non-hospitalized attendants’ hands’ bacterial growth.

Materials and Methods: In this study, the samples taken from the hands of attendants who were accompanying the hospitalized patients were examined. As a control group attendants who were not hospitalized was chosen. The samples were taken from the attendants’ hands and between the fingers using the swap which was wetted by steril serum physiological. Samples were inoculated to bood agar (BA) and eosine methylene blue agar (EMB) immediately. Inoculated plates were incubated 24-48 hours at 370C and growth was evaluated. Growth was identified using colony morphology, Gram stain, catalase and oxidase reaction. Catalaz positive bacteria were investigated for beta hemolysis, colony morphology on BA, Gram stain and microscopic appearance. Growth characteristics of Gram-negative bacilli on EMB and microscopic appearance were determined. All samples were identified by Vitec II.

Results: All participants were women and their average age were 28.93±6.09 (min=18, max=45). It was determined that the rate of bacterial growth was 10% in case group and there was not growth in control group. The difference was statistically insignificant (χ² = 5.263, p = 0.056).

Conclusions: In conclusion, the bacterial growth on 10% of participants’ hands in case group is an important and remarkable result. Being at the border of statistical difference between the two groups suggest that similar studies should be conducted with a larger sample group.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.263-267
Diagnostic accuracy of18F-FDG PET/CT in the evaluation of recurrent ovarian cancer
Authors: Nawi Norazlina Mat , Mohamad Irfan , Khader Mohamed Ali Abdul , Shuaib Ibrahim Lutfi
Published: February 2021

Objective: Ovarian cancer recurrence is often a major problem for patients who have undergone treatment. This prospective study was undertaken to evaluate the diagnostic accuracy of positron emission tomography (PET) with F-18 fluorodeoxyglucose (FDG)/ computed tomography (CT) in patients with suspected for ovarian cancer recurrence.

Methods: A total of 43 women who underwent surgery or chemotherapy for ovarian cancer were enrolled in this study. They underwent18 F-FDG PET/CT scan due to raised CA-125 levels, clinical suspicion of ovarian cancer recurrence, or alterations detected on CT.18 F-FDG PET/CT findings for the women were compared with the final diagnosis.

Results: CA-125 was elevated in 13 patients, while 34 patients presented with alterations on CT, and 9 patients presented with both results’ positivity. 17 patients confirmed to have an ovarian cancer recurrence, all with abnormal findings on PET/ CT. 20 patients remained disease-free during follow-up, all with normal PET/CT findings. There were 9 patients with raised CA-125 levels and normal conventional imaging, all with positive18 F-FDG PET/CT. Among the 30 patients with normal CA-125 levels, 9 patients presented with a positive PET/CT scan. Lymph nodes were the most frequent site. Its sensitivity, specificity, positive predictive value, and negative predictive valuewere 94%, 91%, 77%, and 95%, respectively.

Conclusion: 18F-FDG PET/CT is a useful modality for evaluating the cancer recurrence and extent of the disease. Lymph nodes were the most frequent site. However, there was no statistical significance found between CA-125 levels and 18F-FDG PET/CT findings.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.302-312
Determinant Factors for Selecting the Contraceptive Acceptor Method in the Banjardowo Family Planning Village Semarang
Authors: Ratnawati - , Sembodo Tjatur , Masyhudi -
Published: February 2021

Objective: Indonesia’s population is ranked fourth in the world, while central Java is ranked third nationally. Governments are making efforts to control the population through familyplanning programs. The family planning program to increase the amount of coverage of longterm contraception methods (MKJP) is still low. The purpose of this study is to know the determinant factor associated with the selection of acceptor contraceptive methods.

Materials and Methods: This method uses a cross-sectional approach conducted in a banjardowo semarang village with 103 samples. The inclusion criteria of a sample of women of childbearing age, having a husband, using contraception. The sampling technique used is simple random sampling. Data were analyzed with Chi Square and Fisher Exact Test.

Results and Discussion: The results of data analysis have a significant relationship between the determinant factors with the choice of contraceptive methods, age (p = 0,000; PR = 2,273; CI = 1,184-4,364), the purpose of using contraception (p = 0.04; PR = 1.515; CI = 1.065-2.157 ), Current number of children (p = 0.02; PR = 1.767; CI = 1.075-2.904), people suggesting (p = 0.011; PR = 1.359; CI = 1.359 (1.083-1.705) and previous experience using contraception (p = 0,000; PR = 2, 067; CI = 1,416-3,018) There was no significant relationship on the Education factor (p = 0.754; PR = 0.895; CI = 0.673-1.190), employment (p = 0.274; PR = 1.148 ; CI = 0.885- 1.490), First pregnancy age (p =0.753; PR = 0.953; CI = 0.695-1.305), expected number of children (p = 0.667; PR = 1.054; CI = 0.833-1.333).

Conclusions: determinant factors which shows a significant relationship in determining MKJP or non MKJP contraceptive methods are age, the purpose of using contraception, the number of children desired, the person suggesting and experience using previous contraceptives. mother’s education, mother’s occupation, age of first pregnancy and the number of children expected to be unrelated to the contraceptive method chosen by the acceptor.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.313-317
Gender differences in the dimensions of tricuspid valve orifice and leaflets in the Bangladeshi population - a morphometric study
Authors: Shirin Lubna , Kabir Mohammed Shahjahan , Naushaba Humaira , Islam Mohammed Nasimul , Rahman SM Niazur , Begum Tahamina , Pugazhandhi Bakthavatchalam
Published: February 2021

Background: The present study aims to measure the circumference, length, and breadth of thedifferent leaflets of the tricuspid valve orifice in men and women to enable improved treatmentand management for cardiac patients in future.

Materials and methods: In this cross-sectionalstudy, samples of the cadaveric heart (41 male, 19 female, and age ranging between 20 and70 years) were collected within 12–24 hours of death from unclaimed dead bodies that wereautopsied in the morgues of Sir Salimullah Medical College (SSMC) and Dhaka Medical College(DMC), Dhaka, Bangladesh. Unpaired t-test was conducted to determine significant genderdifferences using SPSS 16.

Results: There were no significant difference in the circumference,length, and breadth of the anterior, posterior, and septal leaflets of tricuspid valves between menand women.

Conclusion :The circumference, length, and breadth of the anterior, posterior,and septal leaflets of tricuspid valves are similar between men and women in the Bangladeshipopulation. Therefore, there will be no specific difference in the surgical and therapeutictreatment for men and women.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.342-347
Prevalence of herbal products use and perceptions on drug-herb interactions among university students in Klang Valley Malaysia- a cross sectional study
Authors: Yan Pan , Hong Tye Kean , Alshagga Mustafa
Published: February 2021

Objectives: This study aimed to identify the prevalence and preference of herbal productsusage and to determine the perceptions of herbal products together with the awareness towardsthe drug-herb interactions among university students in Klang Valley Malaysia.

Methods:A cross-sectional study was carried out by using a self-administered survey questionnairedistributed to students of four universities in Klang Valley Malaysia. A total number of 231responses were collected between December 2018 and March 2019. Statistical analysis wasperformed to evaluate the demographic factors associated with the use and perceptions of herbalproducts and awareness of drug-herb interactions.

Results: Ethnicity and religions were twofactors associated with the use/perceptions of herbal products in the current study. The generalawareness and knowledge about drug-herb interactions were low and inadequate among theparticipants. Furthermore, with regard to awareness on drug-herb interactions, the course/program that students enrolled was found to be the sole factor linked.

Conclusion: The culturalbeliefs and family traditional cultures played critical roles among Malaysia university studentson the use of herbal products. The healthcare stakeholders are suggested to design and to deliverprofessionally structured education to increase the consumers’ knowledge and even customerservice leading to an efficient and safe use of herbal products.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.361-367
Efficacy of Dynamic VS Closed Kinematic Exercise Combined with Stretching in Adhesive Capsulitis- a double blinded randomized controlled trial
Authors: Rajalaxmi V , Vasanthi S , Sathya S , Kirupa K , Mary SM Divya , Aravind Vani , Muthukumaran N
Published: February 2021

Objective: To compare the efficacy of Dynamic exercise and Closed kinematic exercise combined with stretching in adhesive capsulitis.

Background of the study: Adhesive capsulitis is a condition characterized by stiffness and pain in the shoulder joint. It is a painful and disabling disorder of unclear cause in which the shoulder capsule, the connective tissue surrounding the shoulder becomes inflamed and stiff, restricting ROM and causing chronic pain.

Methodology: This was an experimental study design with Pre-Post test. 30 samples were selected from 45 volunteers based on the inclusion criteria. Group A-Dynamic exercise with stretching, Group B-Closed kinematic exercise with stretching, SWD is commonly given to the patients for 1 week.

Results: The result concludes both the groups showed improvement while group A received Dynamic exercise with stretching was comparatively better than the Group B received Closed kinematic exercise with stretching

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.368-373
Benzodiazepine poisoning in Morocco: epidemiological study.
Authors: Detsouli Aicha , Rhalem Naïma , Abidli Zakaria , Jadda Sara , Fekhaoui Mohamed , Amiar Latifa , Soulaymani Abdelmajid , Bencheikh Rachida Soulaymani , Mokhtari Abdelrhani
Published: February 2021

Objective: This study aims to describe the main epidemiological characteristics of benzodiazepine intoxication in Morocco.

Methods: This is a retrospective study of cases of benzodiazepine poisoning reported at the Poison Control and Pharmacovigilance Center of Morocco between 2012 and 2016.

Results: During the period 2012-2016, 1,544 cases of benzodiazepine poisoning were recorded in Morocco. The average age of the addicts is 21.68 ± 14.41 years. According to the data of the study, 70% are Female, with a sex ratio of 2.25.The suicidal act represents a significant percentage with 31.5% of cases. Almost all patients were orally intoxicated with 97.1%.The signs presented are various according to the quantity ingested and the time elapsed before the treatment in particular the psychiatric, neurological, digestive and cardiovascular disorders. Unfortunately, three cases died. The other cases survived with or without sequelae.

Conclusion: benzodiazepines are drugs used in the treatment of several disorders such as anxiety, insomnia and psychomotor agitation. Unfortunately, many people do not know how to use this type of medicine.which exposes them to poisoning, for this reason it is necessary to carry out sensitization campaigns for the good use of benzodiazepines at the national level.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.396-400
The Word Cloud Analysis to Evaluate the Impact of COVID-19 on Environmental Professionals and Environmental Degree Holders: A PAN India Survey
Authors: Choudhury Moharana , Goswami Srijan , Maity Sougata , Chakravorty Arghya
Published: February 2021

Background: In addition to its impact on public health, COVID-19 has had a major impact on the Indian economy and the employment and education on the field of environmental sciences and engineering. This survey study has a mission to focus on how COVID-19 affects PAN India employment and the likely impact on education on the different environmental fields.

Methodology: We have surveyed on PAN India basis by considering different working sectors on environmental field. In our survey, questionnaires circulated by email and different social media like Facebook, WhatsApp and their opinion have been analyzed by analyzing the frequency of the words from their texts / Word Cloud Analysis.

Results and Conclusion: This survey report convey highest frequency of the word “life”, “affecting”, “Covid”, “work” which is similar with “job”, “time” “day”, “home”, “very”, “lockdown” by all environmental professionals, students and researchers. This study suggests a need for more comprehensive and longitudinal evaluation of population needs, allowing the country to design holistic initiatives for affected people.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.414-419
Mesenchymal Stem Cell Conditioned Medium as Good as Methyl Prednisolone in Decreasing Levels of Interleukin 10 and The Degree of Pulmonary Vasculitis in Lupus Mice
Authors: Prabowo Nurhasan Agung , Adnan Zainal Arifin , Nurudhin Arief , Werdiningsih Yulyani , Prasetyo Kukuh
Published: February 2021

Background: Systemic lupus erythematosus is a chronic autoimmune disease that affects target organs. mesenchymal stem cell conditioned medium has immunosuppressive, anti-inflammatory, and immunoregulatory properties in lupus. Methyl prednisolone is a standard drug for lupus with immunosuppressive and anti-inflammatory properties. This study aims to compare the therapeutic effect of mesenchymal stem cell conditioned medium administration compared to methyl prednisolone on interleukin 10 levels and the degree of pulmonary vasculitis of lupus mice.

Methods: The subjects were 24 female mice of Mus musculus Balb/C strain, which were categorized into 4 groups of 8 mice, i.e. the control group receiving 0.5 cc of 0.9% NaCl injection and placebo, the lupus group receiving 0.5 cc of pristane injection and placebo, and the treatment mesenchymal stem cell conditioned medium group receiving 0.5 cc pristane injection and mesenchymal stem cell conditioned medium 0,5 cc, and methylprednisolone group receiving 0,5 cc pristiane injection and methylprednisolone p.o 1,5 mg/kgbodyweight. After 24 days the mice were terminated and kidney and blood samples were taken. Statistical analysis was performed using ANOVA test followed by independent T-test. The p value was considered significant when the p < 0.05.

Results: The study showed that there was no difference on the levels of interleukin level10 among mesenchymal stem cell conditioned medium goup and methyl prednisolone group (CM = 5,94 ± 2,49 pg/mL, mp = 5,86+1,73 pg/mL; p = 1) and the degree of pulmonary vasculitis (CM= 1,94 ± 0,25, MP=1,89+ 0,11 pg/ml; p = 0.667). Mesenchymal stem cell conditioned medium as good as methyl prednisolone in decreasing levels of interleukin 10 and the degree of pulmonary vasculitis in lupus mice.

Conclusion: Mesenchymal stem cell conditioned medium as good as methyl prednisolone in decreasing levels of interleukin 10 and the degree of pulmonary vasculitis in lupus mice

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.426-430
Concomitant Burkholderiapseudomallei and Staphylococcus aureus Infection in a chronic kidney disease patient: A Case Report and Literature Review
Authors: Hamid Norjihan Abdul , Mazlan Mohd Zulfakar , Salmuna Zeti Norfidiyati
Published: February 2021

Melioidosis can happen in humans and animals. It has a wide range of clinical presentations that include asymptomatic infection, ulcers or abscesses of the skin, pneumonia, and multiple internal organ abscesses that may lead to fulminant septic shock. The organism presence in soil and surface of the water. We present a case of a non-diabetic chronic kidney disease patient presented with multiple carbuncles and respiratory melioidosis in which we are able to isolate B. pseudomallei after prolonging the plate incubation for 48-hours. We also suggested available tests in most diagnostic microbiology laboratory for identification of the organism.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.456-458
Phytochemical Investigation of Schleichera oleosa (Lour.) Oken Leaf
Authors: Anjum Noushin , Hossain Md Jamal , Haque Mohammad Rashedul , Chowdhury Akhtaruzzaman , Rashid Mohammad A , Kuddus Md Ruhul
Published: February 2021

Schleichera oleosa (Lour.) Oken. is a medicinal plant of Bangladesh with enormous traditional applications in folk medicine. The current study was designed to isolate the secondary metabolites by successive chromatographic separation of n-hexane and dichloromethane soluble fractions of a methanol extract of leaves of S. oleosa. A total of four compounds were separated and identified as 5,7-dihydroxy-4'-methoxyflavone, stigmasterol, lupeol and betulinic acid. The structures of the isolated compounds were elucidated by analysis of their 1H NMR data and comparison with published values.
Bangladesh Pharmaceutical Journal 24(1): 33-36, 2021
Assessment of Quality of Azithromycin, a Macrolide Antibiotic by NMR Spectroscopy
Authors: Mohammad Shoeb - , Alam Md Farhanul , Islam Md Mazharul , Parvin Nargis , Islam Md Nazrul , Mamun Md Iqbal Rouf
Published: February 2021

A total of forty-five pharmaceutical tablets containing 500 mg azithromycin from 9 (nine) different companies were collected from local pharmacies and evaluated the quality of the antibiotics with standard azithromycin by physical, chromatographic (HPLC), Fourier Transform Infrared (FT-IR), and 1H & 13C Nuclear Magnetic Resonance (NMR) spectroscopic studies. Weight variation of all tested tablets were within 0.1-1.8% which is in the allowed variation of 5%. Two prominent absorption bands were observed at 1723 and 1187 cm−1 in the FT-IR spectrum of all samples and standard for the presence of >C=O and -C-O groups, respectively due to the macrocyclic lactone ring. HPLC coupled with PDA detector (at 210 and 215 nm) gave reproducible results at retention time of 10.5 min for standard and samples. The 1H and 13C NMR spectral data of the standard azithromycin and test samples were found to be identical which led to the conclusion that 1H- and 13C-NMR experiments are feasible tools for qualitative determination of azithromycin in tablets. All the described methods determined the quality of analyzed tablets well.
Bangladesh Pharmaceutical Journal 24(1): 37-44, 2021
A Short Review on the Bioactive Constituents from Six Terminalia Species
Authors: Hussain Mohammad Musarraf
Published: February 2021

Terminalia as a genus has received a great attraction to evaluate and examine the pharmacological potential having their medicinal properties. Different species under Terminalia genus have been used as herbal medicine with various formulations in the treatment of abdominal pain, cancer, cough, conjunctivitis, diarrea, heart problem, leproscopy, urinary tract infection, and sexual related diseases. These properties have been reported to express abundant biological characteristics for example antioxidant, antiparasitic, antibacterial, antifungal, antiviral, and anti-inflammatory. This review has constructed to solicitude the phytochemicals from the genus Terminalia. A total six species belongs to this genus such as Terminalia chebula, T. citrina, T. phanerophlebia, T. belerica, T. catappa, and T. arjuna have been studied and fifty-six phytochemicals with their chemical structures have been reported in this review. Terminalia chebula consists of a higher number of phytochemicals as compared to the other species.
Bangladesh Pharmaceutical Journal 24(1): 76-82, 2021
RECURSOS PEDAGÓGICOS COMO APOIO DOCENTE: UM RELATO DE EXPERIÊNCIA NO CURSO DE ADMINISTRAÇÃO
Authors: Pereira Moraes Jhony , Prá Raquel , Lucas dos Santos Geneia
Published: February 2021

A mudança no perfil dos estudantes ingressantes e dos egressos do ensino superior exige dos docentes a adoção de um novo perfil e a utilização de novas práticas. Com base neste contexto, este trabalho de caráter descritivo tem por objetivo fazer um relato de experiência sobre a prática docente, por meio da apresentação de quatro recursos pedagógicos utilizados na disciplina de Ensino-Aprendizagem em Administração, no Programa de Pós-graduação em Administração da Universidade Federal do Rio Grande Sul (UFRGS). São estas as ferramentas: Kahoot!, EAD Builder, Mindmeister e CANVA. Pretende-se por meio deste contribuir para novas pesquisas sobre metodologias de ensino e recursos pedagógicos.
Palavras-chave: Recursos pedagógicos; Kahoot!; EAD Builder; Mindmeister; CANVA.
ABSTRACT
Changes in the profile of incoming students and higher education graduates requires that teachers adopt a new profile and use new practices. Based on this context, this descriptive work aims to make an experience report about the teaching practice, through the presentation of four pedagogical resources used in the discipline of Teaching-Learning in Administration, in the Graduate Program in Administration of Federal University of Rio Grande Sul (UFRGS). They are the tools: Kahoot!, EAD Builder, Mindmeister and CANVA. It intends to contribute to new research on teaching methodologies and pedagogical resources.
Keywords: Pedagogical resources; Kahoot!; EAD Builder; Mindmeister;  CANVA.
CESARE PAVESE’NİN “AY VE ŞENLİK ATEŞLERİ” ADLI ROMANINDA GERÇEK VE ZİHİNSEL YOLCULUK
Authors: KANARYA Nilay
Published: February 2021

Yirminci yüzyıl çağdaş İtalyan edebiyatının en önde gelen isimlerinden biri olan Cesare Pavese, yazın hayatına ilk olarak şiir yazarak başlar ve daha sonra öykü ve roman tarzındaki yazılarıyla devam eder. Amerikan edebiyatına yakınlığıyla bilinen yazar, 1950 yılında dönemin en önemli edebiyat ödülü olan Strega ödülüne layık görülmüştür. Aynı yılın nisan ayında yayınladığı Ay ve şenlik ateşleri (La luna e i falò) yazarın en önemli eserleri arasında yerini almaktadır. Yapıtın ana karakteri Anguilla, Amerika’da uzun yıllar geçirdikten sonra çocukluğunun geçtiği yere köklerini bulabilmek için tekrar döner. Bu çalışmanın amacı, Cesare Pavese’nin Ay ve şenlik ateşleri adlı romanında yer alan gerçek ve zihinsel yolculuk temasını incelemektir.
A atuação do profissional de enfermagem no processo saúde-doença de crianças com agravos oncológicos: quando a morte se faz presente
Authors: Aires Jeniffer Pereira , Bandeira Andrea Gonçalves
Published: February 2021

O presente estudo teve como objetivo analisar as evidências científicas acerca da atuação do profissional de enfermagem e sua contribuição no processo de terminalidade de crianças com agravos oncológicos. O método foi a revisão integrativa, seguindo as etapas de Whittemore e Knalf, lançando a seguinte questão norteadora: Quais as contribuições da enfermagem no processo de terminalidade em crianças com agravos oncológicos? A busca ocorreu de maio a novembro de 2020, através das bases de dados: BDENF, LILACS, MEDLINE e SciELO. Utilizando os seguintes descritores: criança, enfermagem oncológica, morte - child, oncology nursing, death. Devido à limitação quanto aos estudos relacionados ao tema, utilizou-se dos mesmos como palavras-chave. Os critérios para a inclusão dos artigos foram: estudos qualitativos, quantitativos e estudos teóricos, publicações nos idiomas português do Brasil e Inglês e Espanhol, publicados nos últimos 10 anos, com acesso online e gratuito ao texto completo. Trabalhos que se caracterizavam como: teses, dissertações, textos em anais de congresso e publicações que não respondiam a questão norteadora foram excluídos da amostra final. Através da análise e interpretação dos 8 artigos selecionados, foi possível compreender a importância do profissional de enfermagem na atuação em oncologia pediátrica quando a morte se faz presente. Compreendeu-se que o cuidado vai além dos procedimentos inerentes a profissão, necessitando de um olhar humanizado para poder desenvolver competências como acolhimento do paciente e da família, respeito a autonomia e entender que cada ser humano que cuida do outro, também possuem suas limitações frente à finitude da vida.
Aprendizado do Exame Psíquico por meio de metodologias lúdicas de ensino: Relato de experiência
Authors: Souza José Carlos , Andrade Vinicius Oliveira de , Peres Gustavo Frederico , Monteiro Bruno Massayuki Makimoto , Ono Ben-Hur Vitor Silva , Souza Vitor Cruz Rosa Pires de , Silva Eduardo de Sousa Martins e
Published: February 2021

Introdução: O exame mental é uma ferramenta essencial para a avaliação psíquica do paciente e a averiguação de possíveis transtornos. Dessa forma, a capacitação e a instrução eficiente dos estudantes de medicina e profissionais de saúde em geral é indispensável, a fim de que o exame mental seja feito corretamente. Nesse sentido, o aprendizado do exame mental por meio de metodologias lúdicas de aprendizagem é viável no ensino da semiologia psiquiátrica. Métodos: realizou-se a metodologia ativa de aprendizagem do tipo sala invertida, isto é, método pelo qual os estudantes adquirem um conhecimento prévio para seus estudos, a partir de uma vivência, seja por meio de um vídeo ou de alguma outra forma de arte (e.g., uma peça teatral); por conseguinte, puderam compartilhar conhecimento entre seus companheiros acadêmicos e professor. Relato de Experiência: expõe-se o ensino do exame psíquico, ludicamente, através de diversos gêneros artísticos, como músicas, poesias, crônicas e peças teatrais. Resultados: os objetivos educacionais foram contemplados adequadamente, tendo os alunos da medicina a capacidade, habilidade e competência não só para transmitir os conhecimentos adquiridos, mas também para aplicá-los na concretização das peças teatrais e mesas-redondas realizadas após as apresentações. Não obstante, os temas a serem trabalhados puderam ser antecipados com os vídeos e músicas, favorecendo assim uma aprendizagem mais significativa. Conclusão: o ensino do exame do estado mental, por meio de metodologias lúdicas, no contexto da semiologia psiquiátrica, favorece uma alternativa eficaz na assimilação do conteúdo e fixação do conhecimento.
Terapia por fotobiomodulação: mecanismo de ação e importância clínica no tratamento da osteoartrite de joelho
Authors: Silva Yuri Victor Barbosa , Rezzo Thiago Correia da Silva , Tim Carla Roberta , Vassão Patrícia Gabrielli , Páez Thalita , Garcia Livia Assis
Published: February 2021

A osteoartrite do joelho (OAJ) é uma das doenças articulares degenerativa progressiva mais comuns em todo o mundo e também uma das principais causas de incapacidade e danos à qualidade de vida. A terapia de fotobiomodulação (PBMT, do inglês Photobiomodulation Therapy) através de laser de baixa intensidade (LLLT, do inglês Low Level Laser Therapy) tem mostrado ser um tratamento promissora e com bons resultados para diversas doenças crônicas, incluindo as alterações que acometem o sistema articular. Dentro deste contexto, o objetivo deste estudo é proporcionar, por meio de uma revisão narrativa, uma compreensão das evidências atuais disponíveis sobre o mecanismo de ação e importância clínica da PBMT a laser no tratamento da OAJ. As buscas foram realizadas nas bases de dados bibliográficas do PubMed/MEDLINE, Biblioteca virtual da saúde (BVS), Web of Science e SciELO. Com base nos estudos revisados ​​por pares, os dados laboratoriais em modelos animais experimentais e estudos clínicos mostram que a PBM é capaz de reduzir a morte de condrócitos, estimular a síntese de componentes da matriz extracelular (MEC), atenuar a liberação de mediadores inflamatórios e proteolíticos presente em doenças articulares crônicas, prevenindo assim a degradação do tecido articular e periarticulares. Consequentemente, clinicamente, pode ser observado melhora da dor, funcionalidade e qualidade de vida do indivíduo acometido com OAJ e tratados com a PBMT a laser. Assim, podemos concluir que a PBMT a laser pode constituir um excelente coadjuvante no tratamento da OAJ, uma vez que é um método não invasivo e também apresenta custos relativamente baixos.
COVID-19: Do DNA / RNA vaccines integrate into the genome?
Authors: Pacheco Thyago José Arruda , Silva Victor Carlos Mello da , Souza Danielle Galdino de , Borges Maria Blandina Santos , Silva Sebastião Andrade e
Published: February 2021

The new coronavirus pandemic brought the need for researchers to work tirelessly in the search for therapies or vaccines that would allow control of the spread of the virus around the world. Fortunately there are two RNA vaccines against COVID-19 that have finished clinical tests and are approved in some countries. They are the first third generation vaccines approved in history and in time record. But still have some concerns about safety of DNA/RNA vaccines. Here we bring a discussion about safety of DNA/RNA: can these vaccines be integrated to the genome? In fact, DNA vaccines have an infinite chance to integrate in the cell's genome, but this infinite chance is equal zero when used with RNA-based vaccines. The vaccines based on nucleic acid (DNA and RNA) have been corresponding in advantages, becoming promising alternatives to guarantee the immunization of the new coronavirus.
COVID-19 - The invisible enemy: impacts on students' mental health and coping strategies
Authors: Carneiro Ana Lúcia Basilio , Ramos Semírames Cartonilho de Souza , Brasil Arthur Willian de Lima , Silva Lindair Alves da , Lima Gleydson Grangeiro de , Alves Lincoln Basilio , Melo Mariana Nunes Azevedo de , Melo Conceição de Maria Bezerra de
Published: February 2021

The COVID-19 pandemic is an unexpected historical event with an impact on all aspects of life - especially those of an occupational and mental nature. In a few months, it has altered daily life and social relations and, in addition to social distancing, isolation or quarantine, the world's population has to live with fear, insecurity and human and economic losses. Young people, particularly young women with a psychiatric history and no social support, are more vulnerable to the psycho-emotional consequences of the pandemic. The objective of this study was to observe the impact of COVID-19 on the mental health of students and their coping strategies. This was an observational study with a quantitative and cross-sectional method. The sample consisted of health students from a public university in the state of Paraíba, Brazil. Participants were recruited from the digital platforms in June 2020, a period of social isolation. The link to the Google forms questionnaire was made available on Instagram and WhatsApp. A total of 56 students, most of them women, answered the questionnaire. The most prevalent symptoms during social isolation were anxiety (76.8%), concern (71.4%), fear (62.5%), insomnia (60.7%) and sadness (55.4%). Anxiety, depression, and hopelessness symptoms were more prevalent in younger female students with negative health perception. Complementary therapies and conversations with friends and family stand out as coping strategies. Mental health demands a convergence of efforts and institutional actions are needed to manage the psycho-emotional and neurobiological impact of COVID-19 in an integrated and integral way.
As latências e amplitude no potêncial evocado miogênico vestibular em crianças
Authors: Oliveira Joab Prudêncio de Sousa , Macambira Ysa Karen Santos , Farias Ruth Raquel Soares de
Published: February 2021

Objetivo: O presente estudo teve como objetivo observar se existem diferenças significativas para as latências do VEMP entre crianças e adultos. Metodologia: O estudo trata-se de uma revisão sistemática, com abordagem de natureza quantitativa, os descritores utilizados na pesquisa foram: (Child OR Childhood OR Children OR Pediatric) AND (vestibular evoked myogenic potential OR VEMP OR cVEMP OR oVEMP). A seleção dos estudos e extração dos dados foi realizada apenas por dois pesquisadores, onde os valores médios de latência e amplitude do teste VEMP foram os desfechos procurados nos artigos. Resultados: Nos estudos selecionados, um total de 135 indivíduos foram estudados para a avaliação das latências n1 e p1 do oVEMP, dos quais 62 eram crianças e 73 eram adultos, já para avaliação das latências p13 e n23 de cVEMP foram estudados 50 pessoas, sendo 25 crianças e 25 adultos. Nos procedimentos foram utilizados intensidade entre 100 a 105 dBnHL, com frequência de 500Hz em todos os estudos. As latências dos componentes n1 e p1 e amplitude do oVEMP não possuem diferenças significativas entre as idades, porém nos componentes do cVEMP, é possível verificar uma diferença significativa no componente p13. Conclusão: Os valores das latências do componente de onda e amplitude de oVEMP em crianças não apresenta diferenças significativas em adultos enquanto no componente p13 do cVEMP possuem diferenças significativas por fator de idade.
Aplicabilidade do desenvolvimento tecnológico nas reabilitações orais: relato de caso
Authors: Belo Horácio D’Aguiar Silva , Gondim André Luiz Marinho Falcão , Neves Flávio Domingues das , Traina Andréia Aparecida , Riesco Marta Gonzalez , Frata Katia Arduini , Almeida Neto Luis Ferreira de , Marcelino Karolina Pires , Sartori Ivete Aparecida de Mattias
Published: February 2021

A odontologia reabilitadora está passando por uma grande evolução em todas as áreas de conhecimento, sejam pelas pesquisas cientificas, desenvolvimento das técnicas cirúrgicas e desenvolvimento de materiais. Com o surgimento de novas tecnologias, mais recursos vem sendo adregados na clínica diária, já que materiais e técnicas auxiliam desde o diagnóstico até a confecção das próteses sobre implantes. Objetiva-se, neste relato de caso clínico, demonstrar a importância da associação de várias áreas do conhecimento na reabilitação implantossuportada, valorizando os benefícios da utilização das tomografias computadorizadas cone beam, do sistema CAD/CAM, dos scaners intraorais e das técnicas adesivas nas reabilitações. Paciente com 54 anos procurou tratamento na Fundecto-USP (Fundação Faculdade de Odontologia conveniada à FOUSP) com queixa de ausência dentária na região dos elementos 14 e 15, além de queixas referentes à estética na região anterior. Foi realizado o diagnóstico através de montagem em articulador semi-ajustável, fotografias e enceramento diagnóstico. Apesar da ausência de dois elementos, foi planejada a reabilitação com implante apenas do elemento 15 e aumento dos elementos 16 e 13. A tomografia computadorizada cone beam, permitiu identificar ausência de altura óssea suficiente para instalação de implante na região do 15, então foi planejado a instalação do implante com levantamento da membrana do seio maxilar de forma simultânea. Através de escaneamento intraoral, tecnologia CAD/CAM e informações clínicas, foi realizado o projeto do enceramento virtual das futuras coroas. Após aprovação foi realizada a impressão dos modelos, fresagem das coroas em cera, prova das coroas em cera e fresagem em cerâmica das coroas. Com base na experiência vivenciada parece lícito concluir que os desenvolvimentos tecnológicos têm tornado as reabilitações odontológicas complexas mais rápidas, mais efetivas e previsíveis.
İstikrar ve Adalet Arayışında İbn Zafer'in Yönetim Düşüncesi
Authors: AKMAN Kaan
Published: February 2021

Türk, Arap, Fars, Çin gibi farklı devletlerin tarihteki varlığını ve etkisini araştırmak, devlet olgusunu daha iyi anlayabilmek için oldukça önemlidir. Bu makalede İslam devletlerini incelemek amacıyla İbn Zafer'in Adil Hükümdar kitabı analiz aracı olarak tercih edilmiştir. Çalışmada, 8. ve 12. yüzyıl arasında Akdeniz coğrafyasındaki devletlerin yönetimi ve yöneticilerine ilişkin tespitleri bulunan İbn Zafer'in hayatı, yaşadığı dönemdeki gelişmeler ve eserindeki yönetim düşüncesi incelenmiştir. Makalede, temel meselesi istikrarlı ve adaletli bir yönetim olan İbn Zafer'in yönetim düşüncesi tüm yönleri ile ele alınmaya çalışılmıştır.
Elevated temperature inhibits Mycobacterium shottsii infection and Mycobacterium pseudoshottsii disease in striped bass Morone saxatilis
Authors: Gauthier DT , Haines AN , Vogelbein WK
Published: February 2021

Mycobacteriosis occurs with high prevalence in the wild striped bassMorone saxatilisof Chesapeake Bay, USA. Etiologic agents of mycobacteriosis in this system are dominated byMycobacterium pseudoshottsiiandMycobacterium shottsii, both members of theM. ulcerans/M. marinumclade of mycobacteria. Striped bass occupying Chesapeake Bay during summer months where water temperatures regularly approach and occasionally exceed 30°C are thought to be near their thermal maximum, a condition hypothesized to drive high levels of disease and increased natural mortality due to temperature stress.M. shottsiiandM. pseudoshottsii, however, do not grow or grow inconsistently at 30°C on artificial medium, potentially countering this hypothesis. In this work, we examine the effects of temperature (20, 25, and 30°C) on progression of experimental infections withM. shottsiiandM. pseudoshottsiiin striped bass. Rather than exacerbation of disease, increasing temperature resulted in attenuated bacterial density increase in the spleen and reduced pathology in the spleen and mesenteries ofM. pseudoshottsiiinfected fish, and reduced bacterial densities in the spleen ofM. shottsiiinfected fish. These findings indicate thatM. pseudoshottsiiandM. shottsiiinfections in Chesapeake Bay striped bass may be limited by the thermal tolerance of these mycobacteria, and that maximal disease progression may in fact occur at lower water temperatures.
TINGKAT KONDISI FISIK PESERTA EKSTRAKURIKULER FUTSAL DI MTs PKP JAKARTA ISLAMIC SCHOOL
Authors: Lasma Yunita , Hasbullah Fadlu Rachman , Mazid Kamil
Published: February 2021

Penelitian ini bertujuan untuk mengetahui tingkat kondisi fisik peserta ekstrakulikuler futsal di Mts PKP Jakarta Islamic School. Penelitian ini merupakan penelitian kualitatif dengan menggunakan metode penelitian survei dan teknik pengumpulan data menggunakan tes kondisi fisik. Instrumen tes penelitian dengan pelaksanaan tes kondisi fisik terdiri dari 5 item tes lari 50 meter, shuttle run, baring duduk, vertikal jump, lari 15 menit. Sample penelitian ini berjumlah 20 orang dengan menggunakan teknik pemilihan sample yaitu total sampling yang merupakan siswa Mts PKP Jakarta Islamic School. Berdasarkan data hasil penelitian yang telah dilakukan dapat ditarik kesimpulan secara umum yaitu tingkat kondisi fisik peserta ekstrakurikuler futsal di MTs PKP Jakarta Islamic School masuk dalam kategori kondisi fisik kurang baik.