bluuebunny/crossref_metadata_2025 huggingface dataset:
Hyaluronic Acid: The Reason for Its Variety of Physiological and Biochemical Functional Properties
Authors: Al-Khateeb Rami , Prpic Jelena
Published: April 2019

Introduction:

Many physicians may be unfamiliar with the importance of hyaluronic acid (HA) and its physiological and biochemical functions at cellular level. Despite the vast number of published studies using HA in medical treatments, it is still difficult for the reader to clearly distinguish the different types of HA employed in different medical applications. In addition, published studies do not mention the exact type of HA used or its biochemical properties. Usually, a study mentions only its molecular weight and concentration, which are insufficient to know its exact designed properties or to make a comparison with other types of HA.

Methodology:

This article is intended to summarise the information about native and modified HAs with a focus on explaining their different physiological and biochemical functions in the human body, their different commercially available types, and how they affect the associated medical applications. The goal is to provide a basis to researchers and physicians for distinguishing different types of HA and their properties in order to enhance physicians’ clinical practice in terms of application of different types of HA to treatments and to help the international research community to change the reporting of HA characteristics in published papers. This is necessary to enhance future acquisition of data, with the ability to create an HA data bank for further research and as a reference for different HA types and their medical applications.

Conclusion:

These developments should enhance the scientific and clinical knowledge about HA. Furthermore, the overall approach in this paper can be applied to other similar substances.
The Importance of Community’s Involvement in Park Management towards Sustainable Livelihoods
Authors: Abu Bakar Nor Azlina , Wall Geoffrey
Published: April 2019

This study investigates the impacts of park establishment on communities and how institutional structures, such as customary laws, can influence communities’ involvement in ecotourism. A sustainable livelihoods (SL) approach was adopted as a framework to analyze the relationships among institutional processes and organizational structures (i.e. NCR, institutional arrangement), livelihood strategies and livelihood outcomes. Although Tun Sakaran Marine Park contains beautiful islands, and tourism is the main economic activity, surprisingly, this study found out that local communities are not involved in tourism. Institutional support should be strengthened if ecotourism is to become a livelihood strategy for communities in TSMP.
Encountering the difficulties of Entrepreneurship: Lesson from Ramayana
Authors: Kumar Dinesh , Mahapatra Jyotirmaya
Published: April 2019

Scholars could not come to unanimity on definition of entrepreneurship but agreement exist that an entrepreneur should be a natural leader having thorough understanding of the business and visualize the changes and take calculated risk. Skills and abilities required for entrepreneurship are so great and numerous that it is difficult to find persons having entrepreneurship trailts. Most of the entrepreneurs either fail at early stages or unable to expand the business beyond a small shop. A successful entrepreneur in addition to being a visionary and possessing qualities like innovativeness, resilience, perseverance etc. should have the honest belief in self and unflinching faith in 'Karma' like 'Rama of Ramayana' so that he can face the challenges and pursue the goal with limited resources.Religious philosophy helps the people in developing traits useful in life. Holy books like the Ramayana not just deals with spirituality but management principles hidden in it help an individual to develop entrepreneurship skills and role effectiveness. Primarily, Ramayana is a story and pursuit of the Ramayana does not automatically get translated into entrepreneurship qualities as background was quite different than today's business scenario. However, Rama, a role-model of Gyan-yog and Karm-yog, can be compared with an entrepreneur who started from scraps like entrepreneur but by linking of his goals with social values and following highest standard of ethics, he could make strategic alliances with Sugriva and Vibheeshana and created Ram & Company and inducted less skilled, less equipped but well dedicated Vanar in army and fought against Ravana (the greatest demon) having well equipped army, to make the earth free from devils and liberate Sita and save the dignity of women (social cause). Principles hidden in the Ramayana show holistic vision and, if followed, by an entrepreneur will help him to establish a successful business model.This article is a modest attempt of exploring attributes of Ram and principles/ methodology adopted by him in his fight against Ravana understood through interpretation of stanzas/ verses mentioned in Ramcharit Manas and correlate them with formation of strategy, goal orientation, strategic alliance, change management etc. ideally required by entrepreneurs to establish and grow his business in modern day competitive scenario.
“Market Performance Analysis and Structural Equation Model [SEM] on Vital Facets of Store Attributes on Shoppers' Satisfaction from Retail Store in the Selected Cities of Gujarat State”
Authors: Vyas Parimal H. , Shukla Parag Sunil
Published: April 2019

Organized retailing is creating euphoria amongst Indian consumers drawing them into sprawling malls and shopping plazas in huge numbers. Retailers are offering newer service dimensions to create unique shopping experiences for the customers. By the year 2030, nearly 570 Million people are expected to live in cities, nearly twice the current population of the United States. India's consumption level is set to reach figure of US$ 1.5 Trillion from the current level of US$ 750 Billion by the year 2020 (Deloitte Indian Retail Report, 2013). The present empirical research study is conducted by using exploratory and descriptive research design. An attempt is made by the researcher to decipher the influences of selected store attributes on the shoppers' satisfaction from retail stores and the resultant intention of the shoppers' to recommend the retail store to others. The selected store attributes included in the research study were viz., accessibility of the retail store; range of the products; sales promotional schemes offered; behaviour of staff; store layout; store ambience; store atmosphere, and physical facilities of the retail store respectively. The primary data were collected using structured non-disguised questionnaire from the shoppers' who visit the retail stores for shopping. The samples were conveniently drawn and the data were collected from different retail stores located in the selected Cities of the Gujarat State i.e. Vadodara, Ahmedabad, Surat and Rajkot.The store attributes that influence the shopper satisfaction in the retail store are analysed through the use of statistical methods of Factor Analysis, Market Performance Analysis and Structural Equation Model using Path Analysis. The present study aims at providing valuable information pertaining to the store attributes which exert influence on the satisfaction of the shopper. Furthermore, it seeks to point out the important store attributes which requires special attention of the retailers in the selected cities of the state of Gujarat. This will help the retailers to develop an analytical framework of store attributes influencing purchase preference of shoppers so as to realign their business strategies in order to compete in the ferocious organised retail market.
Opportunities For Entrepreneursin Household Solid Waste Management In Smart City Dharamshala, Himachal Pradesh
Authors: . Sachin , Singh Bhagwan , Yadav Sunita
Published: April 2019

The research paper examines the role of entrepreneurs in solid waste management sector at developing smart city Dharamshala of Himachal Pradesh. The day to day human activities produce household wastes i.e. solid and liquid, among which solid waste is the one which needs to be managed very carefully. The research was conducted at Dharamshala, Himachal Pradesh which is a renowned tourist place. The survey was based on stratified systematic random sampling as the data was collected from every ward of Dharamshala city. The primary data was collected by circulating a questionnaire to the households and secondary data was collected from secondary data resources available both online and offline. The findings revealed that people dispose their household waste by themselves and there are no garbage collection services initiated by municipal corporation Dharamshala. The study explores the opportunities for new entrepreneurs in the field of household solid waste management, since Door to Door (D2D) services are not provided for garbage collection. These entrepreneurs can earn by garbage collection as most of people find no time in disposing their household waste to government authorized dumping sites or government run electric dustbins. The earnings by D2D services can vary between Rs. 2,57,970to Rs.10,97,800. The study reveals that most of the people dispose their household waste at open dumping sites or in plastic bins provided by government instead of government run electric dustbins. The reason behind is lack of awareness in using government run electric dustbins, choked underground dustbins and not following the practice of waste separation. If, municipality Dharamshala would start disposal plants, problem of poor waste management can be solved better.
Evaluating the promotional strategy of Pro Kabaddi League through Response Hierarchy Model
Authors: Mishra Sunit Kumar
Published: April 2019

In this study, we are trying to study the different promotional strategies towards popularizing thetradition Indian game- Kabaddi. Study speciallycovers how the pro Kabaddi league got the global platform with the support ofcelebrities, media and other promotional tools. Using response hierarchy model we have tried to analyzethe responses of kabaddi viewers in all the three stages i.e. cognitive stage, affective stage and behavior stage and the impact of different promotional strategies during this stage. Keywords :Kabaddi league, promotional strategies, hierarchy model
Measuring The Relationship Between Corporate Social Responsibility And Corporate Image: A Case Study Of Bharti Airtel Ltd. And Bharatsanchar Nigam Ltd (BSNL)
Authors: Pandey Amitabh , Jain Manjula
Published: April 2019

Quite evidentlyorganizationsmake extra efforts to generate a good image in order to ensure customer loyalty and good word of mouth which finally culminates in increased revenues and profitability.Corporate image of the company indicates the corporate identity, marketing communications and individuality of the company. The corporate image is based on the feelings, beliefs and perception the customer and other businesses have in totality about the organization and its various brands.Corporate image is highly influenced by the CSR activities performed by the company for the benefit of the society. The customers get more inclined towards a company which performs various CSR activities, and show concerns towards the social causes, environment and raising standards of the society at large, providing quality services which have no harm on the environment. Positive corporate image is a long time asset for the organisations irrespective of their size. In context of Indian telecom sector, very few studies are available where researchers have identified the various areas of corporate social responsibilities or have measured the connection between CSR and corporate image. This study has been conducted to addresses this research gap .The main purpose of the study is to measure relationship between corporate image and corporate social responsibility of the telecom companies and facilitates comparison of the CSR activities of the two companies in the sample i.e. BhartiAirtel Ltd and Bharat Sanchar Nigam Limited. The sample size of the study is 1000 customers comprising 500 Airtel and 500 BSNLcustomers each. The study reveals that corporate social responsibility is found to be significant predictor of corporate image of the telecom company.Indulgence of the telecom companies in CSR activities lead to makinga positive and sustainable image of the company in the market and proves it to be adding to organisationalcitizenship behaviour
Interrelationship Between Industrial Project Risk And Its Characteristics: A Study Based On Structural Model (sm)
Authors: Parihar Shwetank , Bhar Chandan
Published: April 2019

The paper presents a methodology which traces the interrelationship between the project risk and project characteristics, it studies the risk factors and the factors that define project characteristics by the help of literature survey and expert discussion.Amathematical relationship is also developed that includes the effect of risk mitigation on a particular risk. The risk factor when analyzed with both the probability of occurrence and effect of mitigation gives the impact value for that risk. Then we have developed a model in AMOS software for analyzing the effect of risk factors and project characteristic factors on each other, the high value of estimate in between the two proves their interrelated.
Understanding Employees' Perspective on Employment Relations: AStudy on Selected Small Enterprises in India
Authors: Mishra Abhishek
Published: April 2019

Aconsiderable portion of the Indian economy operates under the Small Enterprises or SEs where the studies on employment relations have largely remained neglected due to some reason or other. As such research in the field of employment relations in SEs will make a fruitful contribution to the existing ER/HRM literature (Wilkinson, 1999). There is complete lack of studies on employees' perspectives in the field of employment relations undertaken from an Indian perspective. Employment relations in the Indian SEs are intricate, complex and understudied due to the precarious nature of employment and the absence of HRM mechanism. Therefore, it becomes imperative to understand how employees perceive employment relations inselected SEs in India. The sample consisted of 40 enterprises belonging to SEs in India. The author has ascertained 'Mixed' research methods for the present research. Finally, discussions have been made highlighting employees' perspectives on employment relations in selected SEs in India.
A Study On The Economic Impact Of Handloom Co-operatives On Weavers
Authors: Datta Dibyendu Bikash , Agrawal Bikas
Published: April 2019

Aco-operative society is an independent people's association voluntarily united to fulfill their basic economic, social and cultural requirements by means of a collectively owned and democratically controlled activity. The co-operative movement was an awakening movement for handloom and its associated activities. The handloom co-operative societies played a vital role in our country's economy. The societies provided employment as a source of livelihood for millions of handloom weavers. It is an organization for the deprived and innocent person and takes care of the challenges and the growth strategy by providing strategic inputs on the sector they belong. The development and rapid growth of handloom co-operatives are therefore of vital importance. The Government introduces several schemes to increase the competitive strength of the handloom co-operatives. However, not all handloom co-operatives are well managed and well run. The growth performance of a co-operatives establishes the development of other institutions, middlemen, master weavers, independent weavers, and other beneficiaries. Well-performed co-operatives safeguard the handloom sector since they defend the member weavers and afford a counterbalance with the master weaver. The failure of the handloom co-operative societies will produce substantial losses not only to members and society, but also to the community at large. The powerloom is a clear threat, but can be challenged by unique handloom products that can be marketed locally or abroad, unlike powerloom articles. Based on fieldwork, this study analyzes the distribution of income between handloom co-operatives member weavers and non-member weavers.It also analyzes the variations in the expenditure on essentials and traces out the difference in savings and investment pattern of members and non-member weavers. This study was undertaken in Bishnupur Municipality, Bankura District, West Bengal. Athree-stage sampling procedure was followed for sample selection and the responses from the questionnaires are analyzed to test statistically significant differences between the members and non-members. The results revealed that co-operatives have contributed significantly to improve the economic conditions of the weavers. The non-member weavers should become member weavers to get the benefits as enjoyed by the member weavers and increase their social and economic status in the society
An Empirical Study of Celebrity Endorser and Public Service Advertising
Authors: Singh Krishna Pal , Singh Anurag
Published: April 2019

The purpose of this research is to examine the mediating role of endorser's credibility on the relationship between endorser's attributes and attitude of respondents towards public service advertising effectiveness. The data was observed through a questionnaire in order to study the objectives. Total study 257 respondents were approached and only 200 questionnaires were found suitable. Convenient sampling technique was employed to collect the data in Varanasi city. Factor analysis was used to find the attributes of celebrity endorser which have influence on the credibility of celebrity endorser. Based on the data analysis, through exploratory factor analysis, Attractiveness, Trustworthiness, Similarity and Expertise were found as the main components of celebrity endorser's attributes. The statistical tool regression analysis was used to study the nature of relationships among the attributes of celebrity endorser, credibility and attitude in relation to public service advertising effectiveness. The mediating effect of celebrity endorser's credibility on the attitude of respondents towards public service advertising was checked by applying the linear regression. The research ends with the conclusion and managerial implications.
Usage and Acceptability of the iBobbly App: Pilot Trial for Suicide Prevention in Aboriginal and Torres Strait Islander Youth (Preprint)
Authors: Tighe Joseph , Shand Fiona , McKay Kathy , Mcalister Taylor-Jai , Mackinnon Andrew , Christensen Helen
Published: April 2019

BACKGROUND

The proliferation of mental health apps purporting to target and improve psychological wellbeing is ever-growing and also concerning: Few apps have been rigorously evaluated, and, indeed, the safety of the vast majority of them has not been determined. Over 10,000 self-help apps exist but most are not used much after being downloaded. Gathering and analyzing usage data and the acceptability of apps are critical to inform consumers, researchers, and app developers.

OBJECTIVE

This paper presents pilot usage and acceptability data from the iBobbly suicide prevention app, an app distributed through a randomized controlled trial.

METHODS

Aboriginal and Torres Strait Islander participants from the Kimberley region of Western Australia completed a survey measuring their technology use in general (n=13), and data on their experiences with and views of the iBobbly app were also collected in semistructured interviews (n=13) and thematically analyzed. Finally, engagement with the app, such as the number of sessions completed and time spent on various acceptance-based therapeutic activities, was analyzed (n=18). Both groups were participants in the iBobbly app pilot randomized controlled trial (n=61) completed in 2015.

RESULTS

Regression analysis indicated that app use improved psychological outcomes, although only minimally, and effects were not significant. However, results of the thematic analysis indicated that the iBobbly app was deemed effective, acceptable, and culturally appropriate by those interviewed.

CONCLUSIONS

There is a scarcity of randomized controlled trials and eHealth interventions in Indigenous communities, while extremely high rates of psychological distress and suicide persist. In this environment, studies that can add evidence from mixed-methods approaches are important. While the regression analysis in this study did not indicate a significant effect of app use on psychological wellbeing, this was predictable considering the small sample size (n=18) and typically brief app use. The results on engagement with the iBobbly app were however positive. This study showed that Indigenous youth are early and frequent users of technology in general, and they regarded the iBobbly app to be culturally safe and of therapeutic value. Qualitative analyses demonstrated that iBobbly app use was associated with self-reported improvements in psychological wellbeing, mental health literacy, and reductions in shame. Importantly, participants reported that they would recommend other similar apps if available to their peers.
Hannah Arendt on Proper Education for Politics
Authors: Anowai Dr. Eugene C.
Published: April 2019

This paper examines the writings of one of the most influential political philosophers of our time Hannah Arendt. It focuses especially on her views regarding “The Crisis in Education”, where she asserts that “education is the point at which we decide whether we love the world enough to assume responsibility for it and by the same token save it from that ruin which, except for renewal, except for the coming of the new and young, would be inevitable. Hannah Arendt’s work points towards how we can fall short in our responsibility for, and love of, the world, and for that, education can become complicit in the erosion of a vibrant and robust public realm, the realm of politics. So education should aim at preparing the child for this challenge. In this regard, Arendt’s work takes on a prophetic character, because it denounces a process of alienation in respect to a world that is still ongoing in the field of education.
A STUDY OF THE AVAILABILITY OF MEDICINES FOR THE TREATMENT OF HIV-INFECTED PATIENTS IN THE REPUBLIC OF BASHKORTOSTAN
Authors: Mironenkova Zh. V. , Davletianova A. F. , Gabdulkhakova L. M. , Ilunova Y. G. , Ivakina S. N. , Yapparov R. G.
Published: April 2019

According to the order of the Government of the Russian Federation of 01.12.2004 № 715 the disease caused by the virus of immunodeficiency of the person enter the list of socially significant diseases and the list of the diseases presenting danger to people around. Therefore, the aim of the research was to study the dynamics of the volume of procurement of medicines for the treatment of HIV-infected patients and the assortment availability of antiretroviral medicines in the Republic of Bashkortostan. The studies were conducted during the period of 2010–2016 years. The objects were the materials of reporting of the State Budget Health Agency Republican Center for Prevention and Control of AIDS and infectious diseases, electronic cards of government contracts. Methods of research: statistical, marketing, logic-economic, ATC/DDDs. The average growth rate in procurement of antiretroviral medicines is relatively the basic 2010 in monetary terms amounted to 168,52%. The largest share (1⁄2 part) were domestic medicines with one active substance. In value terms, there is a significant reduction of 26,74% in the volume of purchases of imported medicines with one active substance. At the same time, the import antiretroviral medicines were more in demand among combined antiretroviral medicines: their share increased by 28,56%. In natural terms, the share of domestic medicines with one active substance increased by 49,37%, in general, the share of the volume of antiretroviral medicines purchases of domestic production increased by 2,64 times. An analysis was conducted of the levels of management of assortment based on the calculation of the coefficients of the latitude of ARVs, regional mesocontours of domestic and imported ARVs of the six of the analyzed ATCgroups 4-th level were formed. The number of average daily doses of DDDs/1000 people/day for ARVs was calculated. It is established that the dominating in 2010–2016 there were ARVs of two ATC-subgroups: non-nucleoside — reverse transcriptase inhibitors (NNRTIs) and Nucleoside — reverse transcriptase inhibitors (NRTIs), which corresponds to the preferred first-line regimen for patients who had not previously taken antiretroviral therapy.
SEARCHING SHEAR FORCES FLOWS FOR AN ARBITRARY CROSS-SECTION OF A THIN-WALLED BAR: DEVELOPMENT OF NUMERICAL ALGORITHM BASED ON THE GRAPH THEORY
Authors: Yurchenko Vitalina
Published: April 2019

Searching problem of shear stresses on outside longitudinal edges of an arbitrary cross-section (including open-closed multi-contour cross-sections) of a thin-walled bar subjected to the general load case has been considered in the paper. Detail numerical algorithm intended to solve the formulated problem using mathematical apparatus of the graph theory has been proposed by the paper. The algorithm is oriented on software implementation in systems of computer-aided design of thin-walled bar structures.
urban peripheries workshop Vol. 1 publication
Authors: Maiju Loukola  , Maiju Loukola  , Bea Tornberg  , Una Auri  , Virpi Nieminen
Published: April 2019

The exposition is a visual and textual map of exploratory projects by 10 Aalto ARTS students and 12 Universität der Künste students in their collaboratory workshop URBAN PERIPHERIES Vol. 1 in Helsinki/Espoo, during 5-20 February 2019.

The exposition is composed by the Aalto ARTS students and their supervisor, and it reflects the interventional works realised by the ARTS + UdK students, and experimental texts realised by the ARTS students after the actual workshop.

The exposition similarly works as a basis for the second part of URBAN PERIPHERIES (Vol. 2) that will take place in UdK Berlin in December 2019. It thus also outlines possible scenarios to be explored on grounds of the first workshop.
Fen Bilgisi Öğretmen Adaylarının Eğitsel İnternet Kullanımına Yönelik Öz Yeterli
Authors: Gökal Hüseyin
Published: April 2019

Bu araştırmanın temel amacı, fen bilgisi öğretmen adaylarının eğitsel internet kullanım öz-yeterlilik inançları (EİKÖYİ) ve bilgisayar destekli eğitime (BDE) bakılıp bu tutumlarını birçok değişken açısından inceleyip bu değişken arasında bir ilişki varmı yokmu ortaya koymaktır. Araştırma Fırat ve İnönü Üniversitesi Eğitim Fakültesi Fen Bilgisi Öğretmenliği bölümünde ders gören 461 öğretmen olma adayıları ile yürütülmüştür. İlişkisel tarama modeline uygun bir yönü takip eden araştırmada, veri toplama aracı olarak “EİKÖYİ Ölçeği”, “BDE Yapmaya İlişkin Tutum Ölçeği” ve araştırmacı tarafından geliştirilen “Kişisel Bilgi Formu” kullanılmıştır. Araştırmanın sonucuna bakıldığında kadın öğretrmen adayları, erkeklere bakıldığında teknoloji ve internet kullanımının daha fazla olarak belirlenirken; EİKÖYİ ve BDE yönelik tutumları arasında farklılık gözlenmemiştir. Bunun yanında fen bilgisi öğretmen adaylarının EİKÖYİ ve BDE yönelik tutumlarına interneti olma durumu, interneti kullanma süresi, sosyal ağ üyeliği olma durumuna göre anlamlı farklılık gözlenmiştir. Araştırma kapsamında BDE yapmaya ilişkin tutum puanları ile EİKÖYİ puanları arasında anlamlı bir ilişki olup olmadığını belirlemek için yapılan korelasyon analizi sonucunda aralarında orta düzeyde ve pozitif yönde ilişki belirlenmiştir
Sınıf Öğretmeni Adaylarının Velilerle İletişim Kurma Yöntemlerinin Kullanımının
Authors: Yinal Azmiye
Published: April 2019

Bu araştırmanın amacı; İlköğretim okullarında görev yapan branş öğretmenlerinin velileri ile iletişim araçlarının kullanım düzeyinin ve bakım düzeyinin belirlenmesidir.
Çalışmanın evreni, 2018 öğretim yılında Lefkoşa'daki 6 ilkokul ve bu okullarda çalışan 68 şube (kalıcı ve sözleşmeli) oluşturmaktadır. Çalışmadaki tüm çalışma evrenine ulaşılmıştır.Toplamda 67 kişi değerlendirilmiştir.
Yapılan bu araştırmada anket modeli kullanılmıştır. "İlköğretim Okulu Öğretmenlerinin Ebeveynler ile İletişim Kurma Yolları" ölçeği veri toplama aracı olarak kullanılmıştır ve ölçek 5’li Likert tipi olup 2010 yılında Coşkun tarafından geliştirilmişitr.. Bu çalışmada ölçek iki bölümden oluşmaktadır. Birinci bölümde, "yaş, cinsiyet, branş, görev türü, eğitim durumu, mesleki kıdem ve iletişim kursu" değişkenlerinden oluşan kişisel bilgi formu ve ikinci bölümde önem derecesini ve gerçekleşmeyi ölçmeyi amaçlayan 47 davranış bulunmaktadır.
Estudio y análisis del espacio urbano en «Poemas puros. Poemillas de la ciudad», de Dámaso Alonso
Authors: Ramírez Riaño Adrián
Published: April 2019

Resumen: En este trabajo se trata de estudiar los poemas de juventud de Dámaso Alonso Poemas puros. Poemillas de la ciudad desde la perspectiva espacial. En especial, se tratará de dilucidar si, como apela en el título del poemario, existe en su obra de juventud poesía de entorno urbano o de ciudad. Para ello, en primer lugar, nos basaremos en la producción de poesía urbana coetánea y de textos críticos y filosóficos que hayan estudiado el espacio de manera estilística y sociológica, para después analizar los poemas de la segunda parte del libro.
Modelo de autómatas celulares para la dinámica de un mercado financiero
Authors: Martínez Juan José María
Published: April 2019

Se presenta un modelo de mercado artificial generado por agentes heterogéneos para simular los hechos estilizados observados en mercados reales. Este modelo, desde un enfoque minimalista, pretende reproducir dichos fenómenos con el mínimo costo paramétrico y generar una heurística escalable en complejidad a partir de una microfundación estocástica y un mecanismo de precios que incluye racionalidad acotada, imitación, adaptación y “estados de ánimo” del mercado.
La ventaja del oficialismo en las elecciones municipales de la provincia de Buenos Aires
Authors: Battocchio Matias
Published: April 2019

Este trabajo testea la existencia de una ventaja del oficialismo en las elecciones municipales a intendente de la provincia de Buenos Aires entre 1983 y 2015, con un diseño de regresión discontinua, para el Partido Justicialista y la Unión Cívica Radical. Los resultados muestran que la UCR goza de una ventaja del oficialismo del orden de 20 puntos porcentuales, mientras que para el PJ es menor y no significativa estadísticamente. Aunque esta ventaja sea inusual en los países en desarrollo, su presencia es consistente con Klašnja y Titiunik (2017) donde la desventaja del oficialismo se explica por un sistema con partidos políticos débiles y límites a la reelección de los intendentes; dos características que no se presentan en Buenos Aires.
On the Space/Time of Information Literacy, Higher Education, and the Global Knowledge Economy
Authors: Nicholson Karen
Published: April 2019

Local sites and practices of information work become embroiled in the larger imperatives and logics of the global knowledge economy through social, technological, and spatial networks. Drawing on human geography’s central claim that space and time are dialectically produced through social practices, in this essay I use human/critical geography as a framework to situate the processes and practices—the space and time—of information literacy within the broader social, political, and economic environments of the global knowledge economy.

 As skills training for the knowledge economy, information literacy lies at the intersection of the spatial and temporal spheres of higher education as the locus of human capital production. Information literacy emerges as a priority for academic librarians in the 1980s in the context of neoliberal reforms to higher education: a necessary skill in the burgeoning “information economy,” it legitimates the role of librarians as teachers. As a strategic priority, information literacy serves to demonstrate the library’s value within the university’s globalizing agenda.

While there has been a renewed interest in space/time within the humanities and social sciences since the 1980s, LIS has not taken up this “spatial turn” with the same enthusiasm—or the same degree of criticality—as other social science disciplines. This article attempts to address that gap and offers new insights into the ways that the spatial and temporal registers of the global knowledge economy and the neoliberal university produce and regulate the practice of information literacy in the academic library.

Pre-print first published online 12/09/2018
Wages for Intern Work
Authors: Wildenhaus Karly
Published: April 2019

While no comprehensive studies have yet been published quantifying the extent of unpaid internships within archives and libraries, their prevalence is easily recognized as widespread. Unpaid internships are offered and facilitated based on the implication that they correlate positively to future job prospects, although recent studies point to evidence that complicates this idea. Instead, the prevalence of unpaid internships may negatively impact efforts for diversity and inclusion among information workers while contributing to greater precarity of labor throughout the workforce. Meanwhile, professional organizations and academic programs often do not discuss the realities of unpaid internships, and some MLIS programs require or encourage students to work without remuneration for course credit at their own expense. Situating unpaid internships within larger questions of economic access, labor laws, indebtedness, and neoliberalization, this paper advocates for the denormalization of unpaid internships within archives and libraries, especially for those institutions that articulate social justice as part of their institutional values. Although rendering these positions obsolete is likely beyond the power of any one entity, this paper identify strategies that can be taken at the individual- and institutional-level to advance economic justice and the dignity of all work that occurs in our respective fields.

Pre-print first published online11/25/2018
Plerixafor for patients who fail cytokine-or chemotherapy-based stem cell mobilization: Results of a prospective study by the Polish Lymphoma Research Group (PLRG)
Authors: Giebel Sebastian , Oborska Sylwia , Romejko-Jarosinska Joanna , Dybko Jarosław , Mańko Joanna , Sawczuk-Chabin Joanna , Szymańska Agata , Legieć Wojciech , Czyż Anna , Maruszak Magdalena , Saduś-Wojciechowska Maria , Drozd-Sokołowska Joanna , Steckiewicz Paweł , Ejduk Anna , Paszkiewicz-Kozik Ewa , Ogórka Tomasz , Osowiecki Michał , Targoński Łukasz , Taszner Michał
Published: April 2019

Autologous hematopoietic stem cell transplantation (autoHSCT) requires collection of sufficient number of hematopoietic stem cells. The goal of this study was to evaluate efficacy of plerixafor used in patients with lymphoid malignancies failing conventional stem cell mobilization.

This was a prospective, non-interventional study. All consecutive patients (n = 109) treated with plerixafor in 11 centers were reported. The drug was used either in case of previous mobilization failure (n = 67) or interventionally, in case of insufficient CD34+ cell output during current mobilization (n = 42). Successful mobilization was defined as resulting in collection of ≥ 2 × 106 CD34+ cells/kg for single autoHSCT or ≥ 4 × 106 CD34+ cells/kg for double procedure.

The overall rate of successful mobilization was 55% (55% for single and 56% for double autoHSCT). The median total number of collected CD34+ cells/kg was 2.4 (range, 0-11.5) for patients intended for a single transplantation while 4.0 (0.6-16.9) for double procedure. The number of circulating CD34+ cells increased after the use of plerixafor regardless of baseline values. The median fold increase was 3.3 (0.3-155). Data from this observational study confirm high efficacy of plerixafor used in routine clinical practice as salvage for patients with lymphoid malignancies failing conventional stem cell mobilization.
Progress of research on the immune tolerance of chronic HBV infection
Authors: Li Xuemei , Li Xiaoxia
Published: April 2019

Immune tolerance is a specific lack or negative response of T and B lymphocytes to antigen. According to different formation periods, immune tolerance can be divided into central and peripheral tolerances. The immune tolerance of the body to hepatitis B virus (HBV) after infection is the main cause of chronic HBV infection. In this paper, the functional defects of hepatitis B virus e antigen and dendritic cells, hyporesponsiveness of cytotoxic T lymphocyte, variation of helper T lymphocytes and cytokines, HBV genotype and genome, and the role of host gene polymorphism in the formation of immune tolerance in chronic HBV infection and its related research progress are introduced briefly.
Pengaruh Kompetensi Dan Komitmen Profesional terhadap Motivasi Kerja Auditor ( Studi Empiris Pada Inspektorat Kabupaten Aceh Utara )
Authors: Murhaban Murhaban
Published: April 2019

This study aims to determine whether the professional competence and commitment affect the auditor's working motivation at the Inspectorate of North Aceh district. The research method in this study is causal research design with the auditors of Inspectorate of North Aceh district as samples. This study was conducted in 2011. Data used is primary data that were obtained from questionnaires and distributed directly to the auditors in North Aceh district Inspectorate. The data analyzed in this study were compiled from questionnaire respondents regarding the competence, commitment and motivation of professional auditors. The method of analysis in this study is a qualitative analysis method by testing the quality of the data and classical assumptions testing and then the data will analysis by multiple linear regressions with t-Test and F Test. The results showed that the competence does not give effect partially on Auditor’s working motivation in North Aceh District Inspectorate, while the profession 's commitment partially has an effect on working motivation to auditors in North Aceh District Inspectorate. Simultaneously, competence and professional commitment has an effect working motivation of auditors in North Aceh District Inspectorate.
Pengaruh Financial Leverage, Likuiditas, Pertumbuhan Asset, dan Ukuran Perusahaan terhadap Beta Saham Pada Perusahaan Manufaktur Yang Terdaftar di Bursa Efek Indonesia
Authors: Handayani Desi Wury
Published: April 2019

The purpose of this study is to investigate the influence of financial leverage, liquidity, asset growth, size on the beta stock in manufacturing companies in Indonesia Stock Exchange. The sample in this study is manufacturing companies listed in Indonesia Stock Exchange during the 5 periods (2008-2012). Total samples are 58 companies. The sample selection is done by using the method of stratified random sampling. The multiple linear regression analysis was used to test the hypothesis.This research found that asset growth has significant effect on systematic risk, while variable financial leverage, liquidity, sizedid not have significant effect on systematic risk. The purpose of this study is to investigate the influence of financial leverage, liquidity, asset growth, sizeon the beta stock in manufacturing companies in Indonesia Stock Exchange. The sample in this study is manufacturing companies listed in Indonesia Stock Exchange during the 5 periods (2008-2012). Total samples are 58 companies. The sample selection is done by using the method of stratified random sampling. The multiple linear regression analysis was used to test the hypothesis.This research found that asset growth has significant effect on systematic risk, while variable financial leverage, liquidity, sizedid not have significant effect on systematic risk.
Pengaruh Risiko Pembiayaan Musyrakah dan Risiko Pembiayaan Murabahah terhadap Profitabilitas Pada Bank Umum Syariah di Indonesia
Authors: Afrianandra Cut , Mutia Evi
Published: April 2019

The purpose of this study is to examine and analyze the effect of Musharaka financing risk and the risk of murabaha financing to profitability in Indonesian Islamic banks. The target population of this research is Islamic Banks in Indonesia that registered for three consecutive years. Based entire population, there are 11 Islamic bank for 3 years with 33 observation data. The multiple regression analysis model in used to test the hypothesis. The results of this study indicate that the risk of Musharaka financing and murabahah risks simultaneously affect on profitability. In partial Musharaka financing risk and the risk of murabaha financing have positive influances on profitability.
INSTITUTIONAL INVESTORS, LEVERAGE, DAN PROFIBILITAS TERHADAP FLEKSIBILITAS AKUNTANSI PERUSAHAAN
Authors: Islahuddin Islahuddin , Akramadina Akramadina
Published: April 2019

Abstract            The purpose of this study is to examine and analyze the influence of institutional investors, leverage, and profitability for firms accounting flexibility. The population of this study is manufacturing companies listed in the Indonesia Stock Exchange between 2009 and 2011. This study is a hypothesis testing research that involve 51 firms.            The data is obtained from audited financial reporting period between 2009 and 2011. This study found that institutional investors, leverage and profitability simultaneously have influence for firm accounting flexibility, institutional investors has positive influence for firm accounting flexibility, leverage has negative influence for firm accounting flexibility and profitability has negative influence for firms accounting flexibility.            Keywords:  Institutional investors, leverage, profitability, and firms accounting flexibility
Pengaruh Kemandirian Keuangan Daerah, Diferensiasi Fungsional Dan Spesialisasi Fungsional Terhadap Tingkat Pengungkapan Wajib Laporan Keuangan Pemerintah Daerah
Authors: Suparno Suparno , Nanda Riska
Published: April 2019

The purpose of this study was to examine the effect of local financial independence , functional differentiation and functional specialization of the level of mandatory disclosure of financial statements of local government . The average level of mandatory disclosure of the financial statements of local government in regencies/ cities in Aceh amounted to 48.65 % . The data used are secondary data from the financial statements of the second level governments . Total population in this study were 23 regencies/ cities in Aceh 2013-2014 fiscal year . Statistical method used to test the hypothesis is multiple linear regression . The results showed that, simultaneously local financial independence, functional differentiation and functional specialization affect the level of mandatory disclosure of financial statements of local government. Partially local financial independence affects the level of mandatory disclosure of financial statements of local government, functional differentiation affects the level of mandatory disclosure of financial statements of local government, and functional specialization affect the level of mandatory disclosure of financial statements of local government.
THE ASSESMENT EFFECTIVENESS OF ANTIARRHYTHMIC THERAPY WITH AMIODARONE OF ATRIAL FIBRILLATION PAROXYSMS AT THE PREHOSPITAL STAGE IN DIFFERENT PATIENTS AGE GROUPS
Authors: Truhanova I. G. , Zinatullina D. S. , Polyakov I. A. , Sadreeva S. H.
Published: April 2019

A retrospective content analysis of 210 emergency medical call cards with paroxysms of atrial fibrillation up to 48 hours was carried out in order to analyze and improve the algorithm of prehospital therapy of emergency arrhythmias based on the study of the peculiarities of amiodarone action in elderly and young patients in emergency care.
FEATURES AND ORIENTATIONS OF TRANSPORT OF OXYGEN AT PATIENTS WITH HEMORRHAGIC SHOCK
Authors: Girsh A. O. , Stukanov M. M. , Macsimishin S. V. , Malyuk A. I. , Stepanov S. S. , Korzuk M. S.
Published: April 2019

In work are presented results of the research executed at 285 patients with traumatic shock of varying severity at which defined development of the acute respiratory distress syndrome (ARDS). It is taped that at patients with traumatic shock of the I degree ARDS phenomena don’t become perceptible. At patients with traumatic shock of the II degree emergence of ARDS in 17,8%. At patients with traumatic shock of the III degree emergence of ARDS in 100%.
Development and Correlation between in vitro Drug Release and in vitro Permeation of Thermally Triggered Mucoadhesive in situ Nasal Gel of Repaglinide PVP K30 Complex
Authors: Pathak Kamla , Kumar Anil , Yadav Ekta
Published: April 2019

The aim of the investigation was to develop and evaluate thermoreversible in situ nasal gel formulations of repaglinide (REP) and to establish correlation between its in vitro release and ex vivo permeation profiles. The solubility of REP was
enhanced by preparing solid dispersions (SDs) with hydrophilic carriers (PVP K30/ PEG 6000/ poloxamer 188) in different weight ratios. REP: PVP K30 (1:5) was selected as the optimized SD as it showed highest enhancement in solubility (405%). The
optimized SD was characterized by SEM and DSC and incorporated into a blend of thermoreversible and mucoadhesive polymers (poloxamer 407 and carbopol 934 P) by cold technique to form in situ gels (F1-F6). The prepared in-situ gels were evaluated for
various pharmacotechnical features and the formulation F3 exhibited least gelling time of 6.1± 0.20, good mucoadhesive property to ensure sufficient residence time at the site of application and a %CDR of 82.25%. The ex vivo permeation
characteristics across goat mucosa can be summarized as CDP of 78.7%, flux = 6.80 mg/cm2/h; permeability coefficient of 2.02 mg/h and zero order kinetics. On correlating the CDR profile of F3 with that of its CDP profile, a R2 value of 0.991 (slope=
0.921) was observed. The value of slope approximating one, suggested that almost entire amount of drug released from F3 was capable of permeating across the nasal mucosa, ex-vivo indicating that in-situ nasal gels of REP for systemic action can be
successfully developed for the management non-insulin dependent type-II diabetes mellitus.
FORMULATION DESIGN AND OPTIMIZATION OF FLOATING MATRIX TABLETS OF CIPROFLOXACIN HCL BY USING HPMC AND ETHYL CELLULOSE WITH EXPERIMENTAL DESIGN
Authors: Pasa Gourishyam , Choudhury Prasanta Kumar , Panigrahi Ghanshyam , Maharana Biswajeet
Published: April 2019

The oral floating matrix tablets of Ciprofloxacin Hydrochloride were formulated by Experimental design by using HPMC K100M and Ethyl Cellulose as the retardant polymers each with three different levels with an approach to increase gastric residence and thereby improve drug bioavailability. From FTIR results it was confirmed that there is no chemical interaction between the drug with the excipients used in tablet formulations. Also, there was no shift in the endotherm of in the drug- excipients mixtures indicating compatibility of drug with all the excipients. All the tablets were prepared by effervescent approach in which Sodium bicarbonate was added as a gas generating agent. Floating Matrix tablets were prepared by direct compression method and prepared tablets were evaluated for weight variation, percentage friability, hardness and drug content studies. All the formulations showed compliance with pharmacopeia standards (I.P. 1996). Floating lag times of all the formulations were within 1 minute and Total floating time of all the formulations were more than 12 hours. In vitro release studies revealed that the release rate decreased with increase polymer proportion of retarding polymers. The formulation CHE9 sustained release of drug for 12 hours with 21% release of drug after 1 hour and more than 97% at the end of 12 hours. From the Kinetic model it was found that the optimized formulation CHE9 showed linearity in case of Zero order (R2: 0.938) and Higuchi model (R2: 0.954). By fitting data to Korsmeyer-Peppas model and ‘n’ value lying above 0.5 indicating non Fickian release.