bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of financial technology to increase financial inclusion in Indonesia
Authors: Kurniasari Florentina , Gunardi Ardi , Putri Farica Perdana , Firmansyah Andy
Published: July 2021

The growth of digital technologies has changed the way of doing financial transactions. Even though the transaction value for financial technology in 2018 grew by 24%, the financial inclusion rate in Indonesia is still low, with 64% unbanked. The aim of the study was to analyze the factors of the growing digital technology that influence customer decisions in choosing financial technology services using customer knowledge as the intervening variable. The growing digital technology is measured using social networking, regulatory services, and financial service facilities variables. The sample of this research focused on the microsegment customers located in Java Island. Statistical data are analyzed using Algorithm PLS. Results show that customer decision in choosing financial technology services was strongly influenced by customer knowledge. Customer knowledge was formed from information gathered from the social network, the formal assurance by the government, the financial service facilities, and financial inclusivity. The study recommends a need to educate, promote, and provide adequate information to increase familiarity and literacy rate with regard to financial technology. The study also recommends an urgent clear government regulation to protect the interests of customers and industries.
Factors affecting the adoption of blended learning strategy
Authors: Al-Ayed Sura I. , Al-Tit Ahmad Adnan
Published: July 2021

The aim of this study is to explore factors affecting the adoption of blended learning strategy. Data was collected using a questionnaire consisting of 42 items, distributed to a random sample of 174 faculty members of Saudi Electronic University and Qassim University. IBM SPSS was used to conduct data analysis. Supporting research hypothesis indicates that student, institutional and learning variables had significant influences on the adoption of blended learning strategy. Considering the findings, it was concluded that the adoption of a blended learning strategy depends not only on the technological aspect of the learning process but also on people, i.e., students who are engaged in the process and motivated teachers who possess the required knowledge and skills. The most important implication of this research is that policy and decision makers in business educational schools are requested to consider factors that had a significant effect on the adoption of blended learning. In doing that, the research contributes to the blended learning knowledge via highlighting the key variables that encourage or hinder the adoption of blended learning strategy.
The relationship between Internet of things and search engine optimization in Jordanian Tele-communication Companies: The mediating role of user behavior
Authors: Nusairat Nawras M. , Al-Gasawneh Jassim Ahmad , Aloqool Abdalrazzaq , Alzubi Khalid N. , Akhorshaideh Abdel Hakim O. , Joudeh Jamal M. , Ibrahim Haya Samih
Published: July 2021

This research paper aims to investigate the effect of Internet of Things (IoT) on Search Engine Optimization (SEO) by considering the mediating role of user behavior on this effect. A conceptual research model was developed in accordance with the UTAUT and based on a thorough analysis of extant research. A self-handled questionnaire survey was administered to a purposely selected sample of employees working in telecommunications companies in Jordan. A dataset of 131 usable questionnaires were subjected to data analysis using SmartPLS 3.0. The main findings showed that IoT affected SEO and user behavior. User behavior was also found to be significantly predicted by IoT and to mediate its effect on SEO. The results revealed the significance of SEO as an emerging effective electronic marketing tool in encouraging consumers' adoption of new technologies. The paper ends with a discussion of findings, conclusions, and areas for future research.
Health Problems Accompanying the Call for ‘Stay-at-Home’ During the Pandemic
Authors: GÖKTEPE Muhammed Emin , ATAYOGLU Ali Timucin , KHAN Hammad , ÖZTÜRK Onur
Published: July 2021

The ‘stay-at-home’ order is a kind of mass quarantine strategy and has been enforced globally in response to the COVID-19 pandemic. However, various problems have been reported as well. An electronic research was performed in PubMed and Web of Science databases to determine these problems. This study indicates in a holistic approach to determine some of the potential problems during staying at home mandates. Nutritional disorders, sedentary life, disrupted checkups, eye diseases, increase in alcohol and cigarette consumption, psychological negative influences, sleep disorders, and conflict of generations are among them.
Phytochemical Screening, In-vitro Antioxidant and Cytotoxic potentials of Brachychiton rupestris Leaves
Authors: Mohamed Heba R. , Abdel-Hameed El-Sayed S. , El-Wakil Eman A. , El-Hashash Maher M. , Mohamed Shemis
Published: July 2021

Few studies had been conducted on the phytochemical profile and the biological activities of Brachychiton rupestris. The antioxidant activity of 85% methanolic extract of B. rupestris leaves and its derived fractions was assessed using five different in-vitro assays which are DPPH• assay, phosphomolybdenum assay (TAC), hydroxyl radical (•OH) scavenging assay, nitric oxide radical (NO•) scavenging assay and permanganate reducing antioxidant capacity (PRAC). The total phenolic, flavonoid and flavonol contents were also determined for the different plant samples using Folin-Ciocalteu, aluminum chloride and aluminum chloride/ sodium acetate methods, respectively. In-vitro cytotoxic activity of the crude extract and its fractions against HepG2 cell line was also evaluated via SRB assay. The ethyl acetate fraction obtained from the aqueous methanolic extract of the plant leaves possessed the most potent antioxidant potential according to the different applied assays (DPPH• SC50 = 25.50±0.76 µg/mL, TAC= 311.98±1.19 mg AAE/g ext., •OH SA= 68.42±0.15%, NO• SA= 33.68±1.98% & PRAC = 62.88±0.27%). It also owed the highest amount of phenolics (TPC= 342.10±2.08 mg GAE/ g ext.) whose majority were flavonoids (TFC= 309.82±3.64 mg QE/ g ext.). A strong positive correlation was found between the total phenolic contents of various plant samples and their antioxidant activity. The butanol derived fraction exhibited the most potent cytotoxic activity (IC50 = 8.60 µg/mL). To the best of our knowledge, it is the first study reporting the antioxidant and the cytotoxic activities of B. rupestris leaves. The study revealed that the B. rupestris leaves could be a good source of natural antioxidants which may be applied in food and pharmaceutical industries. They could also be a new opportunity of discovering anti-mutagenic agents.
Stability Indicating Simultaneous Estimation of Phenylephrine HCl and Bromhexine HCl in Combined tablet dosage form by
UV-Spectrophotometer
Authors: T. M. Kalyankar , Wadher S. J. , Bodhankar M. R. , Sayed Mustasin F
Published: July 2021

A novel simple rapid accurate and precise UV spectrophotometric method for simultaneous estimation of bromhexine hydrochloride (BRH) and phenylephrine hydrochloride (PHE) in combine tablet dosage form have been developed. BRH shows absorbance maxima at 246nm and PHE shows 272nm in distilled water after sonication for 20 min. Beer`s law was obeyed at the range of 4-24µg/ml and 5-30µg/ml by BRH and PHE respectively. The method was validated as per ICH guidelines. The validation study data was found to be statistically significant as all the statistical parameters are within the acceptance range (% RSD < 2.0 and S.D. < 2.0) for both accuracy and precision. The force degradation study was carried as per ICH guidelines. The proposed method can be successfully applied for the routine analysis of commercial marked formulation.
Potential Antiseptic of Rhodomyrtus tomentosa leaves extract on Healing wound in Male Wistar rats
Authors: Purwanti Ningsih Endang Sri , Noorlaila Noorlaila , Muhammad Ikhwan Rizki , Budianto Windy Yuliana
Published: July 2021

Background: The process of wound healing is influenced by various factors such as age, hormones, and wound care. Wound care is done to accelerate wound healing which can be done by various methods, one of them is traditional care. Traditional wound care can use medicinal plants. Rhodomyrtus tomentosa is a medicinal plant that has an antioxidant, anti-inflammatory, antitumor and antibacterial content. Thus this study aims to evaluate the effectiveness of the antiseptic solution of the Rodhomyrtus tomentosa leaf extract on wound healing in male Wistar rats. Method: this research is pure experimental research with post test only control group design. Thirty male white rats were divided into five groups, namely negative control, positive control, Rhodomyrtus tomentosa leaf extract 15%, 30%, and 60%. Rhodomyrtus tomentosa leaf extraction was carried out by maceration method with 70% ethano solvent. The extraction results are divided into 3 concentrations (15%, 30% and 60%). The wound healing process was evaluated by measuring the length of the wound manually from 0 to 10 days in each group. Meanwhile, the number of fibroblast cells was calculated through hematoxylin eosin (HE) staining and observed using an Olympus CX41 microscope with a 10x magnification and objective lens magnification in 3 fields. Result: There was a significant difference in the reduction in wound length (p =< 0,000) between the five experimental groups (Rhodomyrtus tomentosa leaf extract solution 15%, 30% and 60%, negative control and positive control. Solution of rhodomyrtus tomentosa leaf extract accelerated the increase in the number of fibroblasts compared to the negative control group (p = 0.003), but did not make a difference (p = 0.403) with the positive control group. Rhodomyrtus tomentosa leaf extraction solution had the same microscopic effect on the number of fibroblasts with a positive control group given 0.9% NaCl solution. Conclusion: There was a significant difference in the number of fibroblasts between all groups, but no difference in wound healing length.
Antihyperglycemic activity of Typha elephantina leaves using in vivo and in vitro Techniques
Authors: Agnihotri Supriya , Singh Gurvirender , Kumar Verma Santosh
Published: July 2021

Looking at the increasing prevalence and inadequate treatments for diabetes mellitus, this study was carried to trace out hypoglycemic potentials of Typha elephantina leaves using in vitro and in vivo studies. α -amylase and α-glucosidase in vitro enzyme inhibition assay were incorporated to determine percent inhibition of Typha elephantina extracts. Typha elephantina methanol extract (TEME) at 125µg/ml in both α-amylase and α-glucosidase exhibited 57.48±1.42 and 53.64±0.92 percent inhibition in contrast to 66.7±0.94 and 70.31±1.25 of standard Acarbose, respectively. However, results obtained in Typha elephantina petroleum ether and chloroform extracts were insignificant. Further TEME antidiabetic properties were investigated by in vivo study, using Streptozotocin induced diabetic rats. Selected 250mg/kg and 500mg/kg doses of TEME were administered orally, which significantly (𝑃 < 0.001) reduces blood glucose of treated animals in contrast to diabetic control. 500mg/kg dose of TEME reduces blood glucose more efficiently. A significant linear rise of body weight and HDL were observed, while there was also remarkable reduction in cholesterol, TG, LDL, VLDL. Reduction in Liver function SGOT, SGPT along with creatinine and urea levels were observed in contrast to diabetic control group. In addition, antioxidant study of Typha elephantina extracts reflected significant results in comparison to that of ascorbic acid in DPPH and H2O2 assay. The whole study signified that Typha elephantina has hypoglycemic potentials.
A Role of Clinical Trial in Management of Hypertension and Medication of Hypertension
Authors: Patel Minesh , Chakraborthy G.S.
Published: July 2021

Clinical trials are essence for the progress of new treatments. Whether a person should engage confide in on their compassionate of the liability and gain for themselves and for society as an entity. Clinical trials are research review in which people volunteer to attempt major treatments, interventions or experiment as a means to forbid, detect, evaluate or manage assorted diseases or medical conditions. Some investigations glance at how people react to a new arbitration and what side effects valor occur. Every new medicine and treatment initiated with volunteers engage in clinical trials. We incur our present high ideal of medical care to studies that have been operate in the past under guidance of the INDIAN Food and Drug Administration (FDA). In addition to Research on new drugs and devices, clinical trials bring a scientific footing for urge and treating patients. Even when researchers do not achieve the conclusion they anticipate; trial results can help point scientists in the mend direction. Blood pressure is great because the larger than your blood pressure is, the larger than your risk of health problems in the future. If your blood pressure is higher than it is putting extra ache on your arteries and on your heart. High blood pressure clouts your heart to work higher to pump blood to the comfort of your body. This causes part of your heart (left ventricle) to congeal. A congeal left ventricle high your risk of heart attack, heart failure and sudden cardiac death. Heart failure. The arena for clinical trials of hypertension management is in transition. The stage of mega trials may not be bygone but is assuredly in decline. Incremental growth in the therapies assessable in the face of a high global disease hardship has imply that hypertension researchers have also attract on getting beat efficacy and value from the available treatments through arrangement improvement, combinations, and algorithms. There has been go on amuse in the role of nonpharmacological compute in cure and management of hypertension.
N-(Chlorobenzyl) Formamide as an Antituberculosis Agent from Multicomponent Reaction Synthesis
Authors: Irma Permatasari Desy Ayu , Ritmaleni Ritmaleni , Nuryastuti Titik
Published: July 2021

Tuberculosis (TB) is an infectious disease caused by M. tuberculosis. A new series of four benzylformamide with chloro substitution were synthesized by multicomponent reaction method and screened for antituberculosis activity against Mycobacterium tuberculosis H37Rv strain. This study was based on amidoalkylation reaction of aromatic-aldehyde, formamide and formic acid at 150oC to give a good yield of benzylformamide. Target compound were isolated, purificated, identified and characterized by GC-MS, FTIR, 1H-NMR, and 13C-NMR then the antituberculosis activity was examined by Microplate Alamar Blue Assay (MABA) and Middlebrook 7H9-7H11 medium in concentration series of 1000 – 1,954 μg/mL, and isoniazid as a positive control. Among the three derivative, N-(2,4-dichlorobenzyl) formamide has the most potential antituberculosis activity up to 500.0 L/mL.
Direct Spectrophotometric Determination of Perindopril Erbumine and Enalapril Maleate in Pure and Pharmaceutical Dosage Forms using Bromocresol Green
Authors: Alhaj Sakur Amir , Balid Bayan
Published: July 2021

In this article, it has been reported new, simple, sensitive and direct spectrophotometric methods for the determination of Perindopril Erbumine (PPE) and Enalapril Maleate (ENL) in pure and in pharmaceutical forms. Spectrophotometric methods are based on the formation of yellow colored ion-pair complexes between PPE, ENL and sulphonphthalein acid dye, Bromocresol green (BCG) into chloroform were measured at the wavelength of 414 and 415nm for PPE and ENL, respectively. The optimal analytical conditions were determined. The obtained complexes (BCG: PPE) and (BCG: ENL) reached maximum absorbance directly after formation at room temperature for a stability period of 24 h. Beer’s law were obeyed in the concentration ranges of (2-20)µg/mL for PPE and (8- 44)µg/mL for ENL, the limit of detection of 0.125μg/mL and 0.230μg/mL were found for PPE and ENL, respectively. The molar absorptivity coefficients were 4.4045*104 L.moL-1.cm-1 for PPE and 1,9330*104 L.moL-1.cm-1 for ENL. The stoichiometry of the complexes formed between PPE, ENL and BCG were 1:1. No interference was observed from common excipients occurred in pharmaceutical formulations and the proposed methods have been successfully applied to determine the PPE and ENL in some pharmaceutical products and in ENL combination dosage forms with hydrochlorothiazide (HCTZ). The proposed methods were successfully validated to be utilized in the quantitative analysis of PPE and ENL in their pure and pharmaceutical products. A good agreement between the developed spectrophotometric methods with the results obtained from official reference methods for the determination of the two drugs in some real samples demonstrate that the proposed methods were suitable to quantify PPE and ENL in pharmaceutical formulations.
The effect of Sulphated cellulose on System of Haemostasis
Authors: Khoshimov Nozim N. , Raimova Guli M. , Nasirov Kabul E. , A. Mamatova Zulayho , Mamadaliyeva Nodira I. , S. Тuraev Abbaskhan
Published: July 2021

Experimental studies and analyses of new compounds with different mechanisms of action on systemic haemostasis are relevant for the identification and development of potential pharmacological preparations. The modified sulphated polysaccharides with anticoagulant and antithrombin activity were studied for haemostasis. Platelet-rich plasma was obtained by centrifugation at 200g for 10 minutes. The remaining citrate blood was further centrifuged at 1500g for 10 min to obtain platelet-poor plasma. The antithrombin activity of the compounds was evaluated In vitro by their effect on the recalcification time, thrombin and prothrombin time of rabbit and human blood plasma stabilized with a 3.8% sodium citrate solution in the ratio 9:1. The results showed that the anticoagulant activity of the studied sulphates increased with an increasing degree of sulphation. Sulphated polysaccharides showed strong anticoagulant activity In vitro. The experimental results showed a significant increase in the coagulation time of blood plasma in tests for prothrombin and thrombin time. These properties of these components are of particular interest, and further detailed studies of the physicochemical characteristics and mechanisms of action of these molecules should be performed, which will eventually allow them to be used as heparin-like drugs.
Efficacy of Eel (Monopterus albus) Extract Gel and Membrane on Incision Wound Healing
Authors: Febriyenti Febriyenti , A Almahdy , Hasibuan Riska Ropika
Published: July 2021

Eel (Monopterus albus) is a freshwater fish that is rich with protein, amino acids, and fatty acids, which are useful as nutrients for accelerated wound healing. The gel is a semisolid dosage form that produces a membrane on the surface of the wound that serves as a wound dressing. Other dosage forms namely membrane has a function to cover the wound and also contain nutrients that play an important rule in accelerating wound healing. The Eel was extracted by a water solvent in an autoclave at 121⁰C for 15 minutes. Eel extract was formulated in a gel and membrane dosage form. Then there are test the effectiveness of the Eel extract gel and membrane on incision wound healing using commercial preparations (gel dosage form) as positive control and without medication as the negative control. The efficacy of Eel extracts from each dosage form could be seen from rat skin that has slashed in the back section taken on days 3, 6, 9, and 12. Eel extract formulated in the membranes form provides the highest value of the tensile strength test. Gel and membrane of Eel extract have effectiveness toward the healing of incision wound in rat compared with the positive control.
Cloning of Acetoacetyl-CoA reductase and Polyhydroxybutyrate synthase genes from the local isolate Bacillus aryabhattai 6N-NRC into Escherichia coli
Authors: El-Metwally Neveen M. , A. Khattab Abd El-Nasser , Shafei Mona S. , F. Allam Reda , M. Ragab Yasser , A. Amin Magdy
Published: July 2021

Polyhydroxybutyrate (PHB) is the most known degradable biopolymer, produced by some genera of bacteria under unfavorable growth conditions. Isolation and cloning of acetoacetyl-CoA reductase (phbB) and polyhydroxybutyrate synthase (phbC) genes from local isolate previously identified as Bacillus aryabhattai 6N-NRC (GenBank accession no. MH997667.1) was achieved. Suitable primers designed for the phbB and phbC PCR approach were used to clone the phbB and phbC genes. The phbB and phbC genes were successfully isolated, cloned and the PCR amplicon 744 bp and 1089 bp corresponding to phbB and phbC genes were identified, cloned with the pET-29a (+) carrying the phbB and phbC genes, transformed and expressed in Escherichia coli BL21. The amplification of the phbB and phbC genes using specific primers of pET-29a (+) plasmid was performed. The open reading frame of phbB sequence was found to be 99.06% identical to the sequence of acetoacetyl-CoA reductase of B. aryabhattai (GenBank accession no. CP024035.1), while the open reading frame of phbC sequence was found to be 87.18% identical to the sequence of polyhydroxybutyrate synthase of B. aryabhattai (Gen Bank accession no. CP024035.1) after DNA sequencing. The analysis of the recombinant proteins from E. coli BL21 recombinant colony by tricine-polyacrylamide gel electrophoresis clarified that the expressed phbB and phbC genes in E. coli BL21 strain showed distinct bands of intensity 26.3 KD and 37.5 KD, respectively.
Prediction model “T2DP” for the onset of Type 2 Diabetes Mellitus
Authors: Alomar Muaed Jamal , Al-Tabakha Moawia M. , Hussein Zeinab Abdirizak
Published: July 2021

Objectives: The objective of this study is to develop a mathematical prediction model for type 2 diabetes based on six chosen risk factors: Obesity, Hypertension, Age, Socioeconomic Status, Physical inactivity, and Family History utilizing published medical literature from 1970 to 2017. Methods: the study provided numeric values for six chosen risk factors that have a direct impact on type 2 diabetes based on the severity. Results: A mathematical equation was developed to predict the remaining years to have type 2 diabetes. Moreover, validation showed that adjusting patient’s modifiable risk factors will positively affect the remaining predicted years to develop type 2 diabetes. Conclusion: T2DP model is a promising tool to predict the remaining years to develop type 2 diabetes. However, it was developed and validated on a theoretical level, and further validation is needed.
F2-Isoprostane Levels in Deoxycorticosterone Acetate (DOCA)-Salt Induced Hypertensive Rats Administered with Coffee-Corn Mixture
Authors: Sugiyanta Sugiyanta , Notopuro Harianto , Nugraha Jusak , Handajani Retno
Published: July 2021

The purpose of this study is to analyze F2-Isoprostane levels in Deoxycorticosterone Acetate (DOCA)–Salt induced hypertensive rats that is given Coffee-Corn mixture. Measurement of blood pressure was carried out by non-invasive methods using CODA instruments. The coffee-corn mixture was made from Robusta (Coffea canephora) obtained from Kaliwining, Jember Regency, and Yellow Corn (Zea Mays) bought from the local market in Jember, East Java, Indonesia. F2-Isoprostane levels were obtained by ELISA examination. The mice’s blood pressure was measured using a non-invasive CODA® blood pressure gauge. Serum F2-isoprostane levels were measured using an F2-isoprostane-ELISA kit that was read with an Elisa reader at a wavelength of 450nm. The results showed that there was a decrease in mean systolic blood pressure in each treatment group, with the most decrease by 41.88mmHg occured in the group that was given a coffee-corn mixture with a ratio of 50% Robusta coffee (Coffea canephora) Kaliwining and 50% yellow corn (Zea Mays). The highest decrease in diastolic blood pressure by 35.25mmHg was also attained in the same group. From the results of serum F2 isoprostrane level examination, there was a decrease in the average level of serum F2 isoprostrane in the treatment group with the most reduction by 51.34pg/mL occured in the group given a coffee-corn mixture with a ratio of 50% Robusta (Coffea canephora) Kaliwining and 50% yellow maize (Zea Mays). Coffee-corn mixture can reduce blood pressure in hypertensive mice through anti-oxidant effects.
Pengalaman Pasien dengan Gagal Ginjal Kronis di RSUD Embung Fatimah Batam
Authors: Natalia Siska
Published: July 2021

Gagal ginjal kronis merupakan salah satu kondisi paliatif, yang berdampak pada pasien harus melakukan cuci darah rutin sepanjang hidupnya. Hasil wawancara singkat dari tujuh pasien yang menjalani hemodialisa didapatkan mereka mengatakan sulit untuk menerima keadaan, mengalami sedih dan depresi, dan takut. Tujuan dari penelitian ini adalah untuk mengetahui pengalaman hidup pasien dengan gagal ginjal kronis yang menjalani hemodialisa. Desain penelitian yang digunakan adalah kualitatif dengan wawancara semi-structured. Didapatkan 11 responden dengan teknik pusposive sampling. Hasil penelitian didapatkan beberapa tema yaitu pasien mengalami: 1) gangguan fisik dengan sub tema kelemahan fisik, sesak napas, kulit gatal 2) gangguan psikologis kecewa dan sedih, 3) gangguan sosial dengan sub tema kurang sosialisasi, kehilangan pekerjaan, butuh dukungan. Kesimpulan bahwa pasien mengalami penurunan kualitas hidup, dengan gangguan fisik, psikologis, dan sosial. Rekomendasi untuk penelitian selanjutnya untuk meneliti hal yang mempengaruhi kualitias hidup pasien dari berbagai rumah sakit.
STUDI KUALITATIF TENTANG KEJADIAN STUNTING PADA BADUTA USIA 6 – 23 BULAN DI WILAYAH KERJA PUSKESMAS PAMBOANG
Authors: Wardawati
Published: July 2021

Stunting merupakan salah satu permasalahan gizi yang dihadapi di dunia. Stunting menjadi permasalahan karena berhubungan dengan meningkatnya risiko terjadinya kesakitan dan kematian. Permasalahan stunting di Kabupaten Majene juga masih perlu diperhatikan. Berdasarkan data yang dari kantor DPPKB lembang Kabupaten Majene diperoleh data bahwa Kecamatan Pamboang merupakan kecamatan yang termasuk dalam prioritas Nasional masalah Stunting dan yang tertinggi adalah Desa Betteng .Tujua penelitian ini adalah untuk memperoleh informasi secara kualitatif tentang  kejadian Stunting pada Baduta usia 6-23 bulan di Wilayah kerja Puskesmas Pamboang Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan fenomenologi untuk mengetahui respon keberadaan manusia yang bertujuan menjelaskan pengalaman seseorang dalam kehidupannya termasuk didalamnya yaitu pengetahuan tentang pemenuhan gizi saat hamil, ASI ekslusif serta sikap dan sikapnya dalam pemberian ASI ekslusif, usia dan jenis pengenalan MP – ASI. Penelitian ini mengambil lima orang informan dan 2 orang informan kunci dengan menggunakan tekhnik purposive sampling. Hasil penelitian menunjukkan bahwa pengetahuan ibu terhadap status gizi anaknya terrutama masalah stunting masih kurang. Rendahnya pengetahuan ibu terkait masalah diatas dikarenakan ketidakhadiran ibu pada saat penyuluhan. Dari kelima informan di dapatkan 1 orang yang tidak memberikan ASI eksklusif kepada anaknya sikap informan terkait  pemenuhan gizi mereka sadar bahwa pemenuhan gizi untuk anaknya itu penting hal tersebut juga dapat dilihat bahwa dari kelima informan tidak ada yang mengalami kejadian BBLR pada anaknya. Adapun saran yang diajukan dalam penelitian ini adalah pengetahuan ibu merupakan faktor yang berhubungan dengan kejadian stunting pada baduta. Perlu adanya program pemerintah yang dapat mendukung  untuk meningkatkan pengetahuan ibu terkait masalah gizi terutama stunting.
HUBUNGAN PERILAKU MASYARAKAT DENGAN PENULARAN PENYAKIT TB PARU DI KECAMATAN SENDANA KABUPATEN MAJENE
Authors: Yulianah Sulaiman
Published: July 2021

Tuberkolosis paru merupakan penyakit infeksi menular yang disebabkan oleh Mycobacterium tuberculosis (TBC) dan paling sering bermanifestasi di paru. Tujuan penelitian ini adalah Untuk mengetahui Hubungan Perilaku Masyarakat Dengan Penularan Penyakit TB Paru di Kecamatan Sendana Kabupaten Majene Tahun 2019.  Jenis penelitian yang digunakan dalam penelitian ini adalah kuantitatif dengan pendekatan Cross Sectional. Populasi penelitian ini adalah semua penderita penyakit TB Paru sebanyak 38 orang dan sampel sebanyak 38 orang. Analisis statistik yang digunakan adalah Chi Square dengan pearson Chi-Square. Hasil penelitian analisis univariat menunjukkan distribusi berdasarkan pengetahuan yang terbanyak adalah pengetahuan baik (97,4 %), distribusi responden berdasarkan sikap yang terbanyak adalah sikap baik (73,7 %), dan distribusi berdasarkan tindakan yang terbanyak adalah tindakan kurang (78,9 %). Hasil analisis bivariat menunjukkan bahwa nilai p = 0,136 > ɑ = 0,05 maka tidak terdapat hubungan pengetahuan dengan penularan TB Paru di Kecamatan Sendana Kabupaten Majene Tahun 2019, nilai p = 0,000 < ɑ = 0,05 dan nilai coefficient contingency sebesar 0,528, maka terdapat hubungan sikap dengan penularan TB Paru dengan tingkat hubungan yang cukup kuat di Kecamatan Sendana Kabupaten Majene Tahun 2019 dan nilai p = 0,003 < ɑ = 0,05 dan nilai coefficient contingency sebesar 0,434, maka terdapat hubungan tindakan dengan penularan TB Paru dengan tingkat hubungan yang cukup kuat di Kecamatan Sendana Kabupaten Majene Tahun 2019. Disarankan kepada petugas kesehatan untuk mempertahankan dan meningkatkan pelayanan kesehatan khususnya dibidang penyuluhan.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN DIARE PADA BALITA DI DESA TALLAMBALAO KECAMATAN TAMMERODO KABUPATEN MAJENE
Authors: Haerani
Published: July 2021

Diare merupakan kumpulan gejala yang disebabkan dari beberapa faktor, dikatakan diare bila adanya perubahan konsistensi tinja lunak ke cair dan frekuensi defikasi lebih dari kebiasaan individu tersebut.

Penelitian ini bertujuan untuk mengetahui Faktor-Faktor Yang Mempengaruhi Kejadian Diare Pada Balita Di Desa Tallambalao Tahun 2018, penelitian ini merupakan penelitian analitik-observasional dengan pendekatan Cross Sectional dengan menggunakan Kuesioner. Populasi dalam penelitian ini adalah semua ibu yang mempunyai balita yang mengalami kejadian diare di desa Tallambalao dan nama balita tercatat di Puskesmas Tammerodo Tahun 2017 sebanyak 39 balita. Tehnik pengambilan sampel yang digunakan dalam penelitian ini adalah (total sampling).

Hasil dari penelitian ini menunjukkan bahwa hasil uji statistic dengan nilai α = 0,05 yang menggunakan uji fisher, pada penelitian ini Status Gizi di peroleh nilai p = 0,020 yang berarti p < α, yaitu ada pengaruh antara status gizi dengan kejadian diare dan ASI eksklusif diperoleh nilai p = 1,000 yang berarti p > α, adalah tidak ada pengaruh antara ASI Eksklusif dengan kejadian diare, sedangkan Perilaku cuci tangan di peroleh nilai p = 0,049 yang berarti p < α, ada pengaruh antara Cuci Tangan dangan kejadian diare.
Postsecondary Teacher Quality and Student Achievement in Florida's Career Certificate Programs Using a Causal-Comparative Study
Authors: Martino Lisa M.
Published: July 2021

Teacher quality and student achievement have shown positive relationships in prior studies of elementary and secondary grade levels in the United States. However, postsecondary career and technical education (CTE) teacher quality and student achievement is an understudied topic. According
to the literature, teacher quality is measured by pedagogical knowledge, level of education, and professional development. For postsecondary CTE teachers, occupational experience is a hiring requirement for teacher quality. Student achievement is measured by test scores and graduation rates.
Postsecondary career certificate programs usually have a summative evaluation with an industry-specific certification test, which assesses the student's employability in the program's field of study by industry standards. The purpose of this retrospective causal-comparative study was to examine
the relationship between postsecondary CTE teacher quality and student achievement in Florida's career certificate programs. An online survey was conducted with 203 postsecondary CTE teachers in Florida. Findings revealed a statistically significant positive relationship between the level
of pedagogical knowledge and educational degree attainment of postsecondary CTE teachers and students' passing an industry certification test. This finding is consistent with prior studies in K-12 grade levels. Recommendations include increasing the pedagogical knowledge and educational degree
attainment of postsecondary CTE teachers to improve student learning outcomes.
Identifying Technical Competencies for Architecture and Construction Education using the Delphi Method
Authors: Jones Jon , Belcher Greg , Elliott Kevin
Published: July 2021

The purpose of this Delphi study was to identify the dominant technical competencies needed to effectively teach architecture and construction at the secondary and postsecondary level and to determine if there are differences of opinion among educators, recent graduates and industry
personnel as to what those competencies should be. To provide instructors with the knowledge and skills that align with industry needs, it was imperative to identify the changing technical competencies needed by the workforce and the instructors who prepare these future employees. A three
round Delphi study was conducted to identify the dominant technical competencies. From a list of 23 technical competencies identified in round one, seven technical competencies emerged as the highest rated in perceived level of importance by the three groups.
The Impact of Smartphone Addictive Use by Students with Learning Disabilities on Social, Psychological and Academic Domains
Authors: Al-Natour Mayada , Al-Ajlouni Khaled , AlKhamra Hatem
Published: July 2021

The current study aimed at identifying the impact of the addictive use of smartphones by students with learning disabilities on the social, psychological and academic domains. The sample of the study consisted of 210 male and female students enrolled in classes of resource rooms of grades five to nine in public and private schools at the Ministry of Education in Amman governorate. The researcher developed two measures to achieve the goals of the study; the first is “a scale to measure the addiction of smartphones use”, which contains 32 items, and another scale to measure the “impact of smartphones excessive use on social, emotional and academic domains”, which contains (30) items. This process was preceded by a review of previous similar pedagogic studies. Validity and reliability significance were extracted. Results revealed that the estimation of the addictive use of smartphones by students of learning disabilities aged 11-15 was rated as average. Results also revealed that impact of smartphone use dominated the social and emotional aspects over the academic. Results call for the need to develop and practise some precocious interventions and early detection of the excessive use of smartphones in general, but above all by students with learning disabilities.
The Use of Fabric Masks in Prevention of Community Transmission of COVID-19
Authors: Saputra Rudi
Published: July 2021

Introduction: COVID-19 (Coronavirus Disease 2019) is a new disease due to SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2) which can be transmitted through droplets. One effort to prevent transmission of COVID-19 is to use a mask. Medical masks are effective in preventing transmission of COVID-19, but their numbers are very limited and are very much needed by medical personnel when treating COVID-19 patients. Therefore, to prevent the spread of COVID-19 more broadly, alternative medical masks are needed, namely by using cloth masks which have not been discussed much about the purpose of their use to the public. Discussion: SARS-CoV-2 is a cause of COVID-19 and infects the respiratory tract, especially in the lungs (pulmo) through the ACE2 receptor (Angiotensin-Converting Enzyme 2). SARS-CoV-2 has a diameter of around 120 nm. Cloth masks as an alternative to the scarcity of medical masks are recommended for public use. The recommended cloth masks are made of cotton or a cloth towel. A cloth mask is able to hold large droplets (> 5 μm), but not small droplets. Conclusion: Cloth masks can be used by the community in an effort to minimize transmission of COVID-19 by holding large droplets, but it is not effective in preventing transmission of COVID-19 because it can still be passed by SARS-CoV-2. Suggestion: Cloth masks can be optimized using nanoparticles to resist SARS-CoV-2.
PENGARUH PEMBERIAN MINYAK ZAITUN Olive oil TERHADAP GAMBARAN HISTOPATOLOGI LAMBUNG TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR Spargue dawley YANG DIINDUKSI ALKOHOL
Authors: Pratama Muhammad Reqza
Published: July 2021

Penggunaan alkohol yang tidak terkontrol dapat menyebabkan berbagai kerusakan pada mukosa lambung, Minyak zaitun sebagai tumbuhan herbal merupakan sumber penting untuk memproteksi dan regenerasi mukosa lambung yang rusak. Penelitian ini adalah penelitian eksperimental laboratorium dengan desain post-testcontrol group design yang dilaksanakan di animal house Fakultas Kedokteran Universitas Lampung dengan menggunakan sampel 30 tikus putih (Rattus norvegicus) jantan galur Sprague dawleyyang dibagi menjadi 5 kelompok yaitu; kelompok kontrol negatif (K-) yang hanya diberikan aquades 2ml/hari, kelompok kontrol positif (K+) yang diberikan alkohol 2,4ml/hari selama 14 hari; kelompok perlakuan 1 (P1) diberikan alkohol 2,4ml/hari dan minyak zaitun 0,27ml/hari selama 14 hari; kelompok perlakuan 2 (P2) diberikan alkohol 2,4ml/hari dan minyak zaitun 0,54ml/hari selama 14 hari; dan kelompok perlakuan 3 (P3) diberikan alkohol 2,4ml/hari dan minyak zaitun 1,08ml/hari selama 14 hari. Data diamati dengan Uji Non-Parametrik Kruskal-Wallis, diperoleh p = 0,000 (p <0,05). Hasil yang diharapkan diperoleh Ho yang diharapkan. Hasil statistik dengan uji Mann-Whitney yang diperoleh juga ditemukan adanya perbedaan yang signifikan pada setiap kelompok.
Coaching Caregiver: Aplikasi Telehealth Berbasis Edukasi dan Konsultasi Kepada Caregiver Pasien Skizofrenia
Authors: Wanami Putri Ni Made Wini Jayesthiwi , Parastan Rovie Hikari , Dyatmika I Kadek Wahyu Putra , Lesmana Cokorda Bagus Jaya
Published: July 2021

Skizofrenia adalah sebuah masalah psikiatri yang serius dan dialami di seluruh dunia. Pada 2018, terdapat 6.7 per 1000 kasus skizofrenia di Indonesia. Penanganan yang direkomendasikan untuk pasien skizofrenia adalah pengobatan farmakologi dan non-farmakologi yang memerlukan dukungan dari caregiver atau pengasuh untuk membantu meningkatkan kualitas hidup pasien. Sebagai seseorang yang terdekat dengan pasien, keluarga memiliki peran penting dalam menjaga dan mengasuh pasien yang terkena skizofrenia. Namun, status quo saat ini menyatakan bahwa caregiver tidak paham bagaimana cara mengatasi pasien skizofrenia dalam berbagai kondisi. Maka dari itu, caregiver harus mendapatkan pelatihan maupun edukasi mengenai pasien skizofrenia dengan harapan caregiver dapat mengasuh keluarga/kerabat mereka dengan baik. Berdasarkan penelitian yang dilakukan Ozkan dan Khatri, dengan menyediakan data psikoedukasi melalui internet/teknologi (telehealth) kepada caregiver, menunjukan adanya perkembangan yang signifikan pada caregiver dalam menangani pasien skizofrenia. Maka, Coaching Caregiver hadir sebagai inovasi dan solusi  untuk membantu caregiver dalam merawat keluarganya yang mengalami skizofrenia. Beberapa aspek yang terdapat di program ini berdasarkan dengan DSM V dan PPDGJ III, seperti informasi dan edukasi melalui video dan artikel, konsultasi dan support dalam pengambilan keputusan, terapi psikososial dan prilaku, dukungan sosial, dan monitoring. Pendekatan berbasis teknologi diharapkan dapat menyediakan layanan kesehatan dan pelatihan untuk lebih banyak orang. Sebagai tambahan, Coaching Caregiver juga diharapkan untuk dapat membekali caregiver dengan pengetahuan dan pelatihan yang memadai untuk merawat keluarga mereka yang mengalami skizofrenia.
SMARTPHONE PULSE OXIMETER: SOLUSI DETEKSI DINI HAPPY HYPOXIA
Authors: Naufal Fachri , Rifa'i Alfiani Zukhruful Fitri
Published: July 2021

Pendahuluan: Coronavirus disease 2019 (COVID-19) merupakan krisis dunia sepanjang tahun 2020. Tidak hanya itu, COVID-19 juga menjadi tantangan karena dapat menimbulkan fenomena happy hypoxia, dimana pasien dengan saturasi oksigen di bawah normal datang tanpa disertai gejala pernapasan atau dispnea.

Pembahasan : Kondisi happy hypoxia yang tidak sesuai dengan teori patogenesis COVID-19 memunculkan berbagai hipotesis terkait mekanisme terjadinya happy hypoxia. Oleh karena pasien tidak merasakan gejala infeksi, dibutuhkan deteksi dini agar pasien mendapatkan pertolongan sesegera mungkin. Kini smartphone telah disematkan oximeter dan dapat digunakan untuk deteksi dini kondisi happy hypoxia.

Simpulan: Pulse oximeter smartphone merupakan solusi efektif karena mudah digunakan di mana pun dan kapan pun sehingga dapat mendeteksi secara dini adanya penurunan saturasi oksigen untuk mendapatkan terapi lebih awal dan dapat berkorelasi untuk menurunkan angka mortalitas COVID-19.
Faktor-Faktor Konversi BTA Penderita Tuberkulosis Paru Di Rumah Sakit Umum Haji Medan
Authors: L. Tobing Ayunda Pratiwi , Roslina Ance
Published: July 2021

Latar Belakang : Tuberkulosis (TB) paru adalah penyakit menular yang disebabkan oleh Mycobacterium tuberculosis. Beberapa yang menjadi faktor risiko terjadinya penyakit TB paru diantaranya adalah umur, jenis kelamin, riwayat OAT, penyakit penyerta seperti DM dan HIV serta konsumsi rokok dan alkohol. Pemeriksaan biakan sputum merupakan gold standard yang digunakan dalam memantau pengobatan pada pasien TB. Evaluasi konversi BTA dari positif menjadi negatif dari bakteri Mycobacterium tuberculosis merupakan indikator yang penting untuk memantau pengobatan pada pasien TB. Tujuan : Untuk mengetahui faktor-faktor yang mempengaruhi konversi BTA penderita tuberkulosis paru di Rumah Sakit Umum Haji Medan. Metode : Jenis penelitian ini adalah penelitian deskriptif dengan pendekatan cross sectional dan mengumpulkan data rekam medis, penelitian ini di lakukan pada bulan Januari 2018 – November 2019 dengan sampel sebanyak 71. Hasil Penelitian : hasil penelitian menunjukkan bahwa konversi BTA terbanyak terjadi pada usia 20-29 tahun, 50,7% berjenis kelamin perempuan, 70,4% tidak memiliki riwayat penyerta DM, 94,4% tidak memiliki riwayat penyerta HIV, 100% tidak memiliki riwayat OAT sebelumnya, 72.4% tidak merokok, dan 86,2% tidak mengkonsumsi alkohol. Kesimpulan : konversi BTA banyak terjadi pada usia muda, jenis kelamin perempuan, tidak memiliki riwayat DM dan HIV, tidak mempunyai riwayat OAT, tidak merokok dan menggunakan alkohol.
BMV-CSC Patch: Sel Punca Jantung dengan Biomimetic Microvessel berbasis HUVEC sebagai Inovasi Potensial untuk Terapi Infark Miokardium Akut
Authors: Sigilipu Yitzchak Millenard
Published: July 2021

Coronary Heart Disease (CHD) is the main global cause of morbidity and mortality. The most common form of CHD is myocardial infarction which contributes to more than 15% of death. Cardiac stem cell-based therapy (CSC) is a promising approach to treat the condition. The main issue hindering efficacy and further development of the approach is the low retention and viability of stem cells after intra myocardial injection on ischemic heart. In order to address the issue, a novel strategy to create a vascularized cardiac patch using the microfluid with hydrodynamic focusing technique. The cardiac patch will be integrated Biomimetic Micro Vessels (BMV) alongside human umbilical vein endothelial cells (HUVEC) on the luminal surface. A study reported that the endothelium of BMV mimics the architecture and natural functioning of the capillaries. Vascularized cardiac patch (BMV-CSC) will release paracrine factors higher than original co-cultured human CSC and HUVEC after seven days of in vitro culture. In acute myocardial infract (AMI) rat model, the BMV-CSC patch induced mitotic activities of cardiomyocytes in peri-infarcted area after 4 weeks of implantation. Significant increase in the density of myocardial capillaries in infarct area compared to the conventional cardiac patch was also reported. The significant benefits of BMV-CSC patch showed that this approach is a potential method for AMI therapy.
Comparison of occult pneumothorax and pneumothorax cases in thoracic trauma: A descriptive, cross-sectional study
Authors: Aslay Semra
Published: July 2021

Background: The emergency department usually takes a supine posteroanterior (PA) chest X-ray imaging in trauma patients. In some cases, pneumothorax is not seen in the chest X-ray because of the patient's position. These cases are called occult pneumothorax. Misdiagnosis of occult pneumothorax in the emergency department may lead to complications such as tension pneumothorax. This study aimed to update patients’ features with occult pneumothorax due to blunt or penetrating trauma.

Methods: In this study, data of 615 thoracic trauma patients admitted to the emergency department between January 2008 and December 2010 were evaluated. In total, 157 patients had undergone both chest X-ray and chest computed tomography and were diagnosed with pneumothorax. Of the 157 patients, 52 were excluded due to some criteria. Data of 105 patient, including their characteristics, trauma types, accompanying traumas, etiology of the chest trauma, chest X-ray findings, and computed chest tomography results were recorded. Data obtained were compared with the results of similar studies conducted in the last 10 years. Chest computed tomography was considered the gold standard for the diagnosis of pneumothorax.

Results: The mean patient age was 36.19 ± 14.74 years. Occult pneumothorax was detected in 8 of 105 patients, giving a 7.6% overall incidence of occult pneumothorax. A traffic accident was the most common cause of etiology. All occult pneumothorax cases were caused by blunt trauma, and tube thoracostomy was performed in all of them. No significant differences were found between pneumothorax and occult pneumothorax cases concerning the etiology, accompanied trauma, intervention types, and trauma reasons (p < 0.05).

Conclusions: This study supports the incidence of occult pneumothorax reported in the literature. When a patient is admitted with thoracic trauma, a physician should carefully evaluate the patient through supine chest X-ray examination. Only one misdiagnosis in trauma patients can be lead to many unintentional clinical and forensic results.