bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep learning based algorithm (ConvLSTM) for Copy Move Forgery Detection
Authors: Elaskily Mohamed A. , Alkinani Monagi H. , Sedik Ahmed , Dessouky Mohamed M.
Published: March 2021

Protecting information from manipulation is important challenge in current days. Digital images are one of the most popular information representation. Images could be used in several fields such as military, social media, security purposes, intelligence fields, evidences in courts, and newspapers. Digital image forgeries mean adding unusual patterns to the original images that cause a heterogeneity manner in form of image properties. Copy move forgery is one of the hardest types of image forgeries to be detected. It is happened by duplicating part or section of the image then adding again in the image itself but in another location. Forgery detection algorithms are used in image security when the original content is not available. This paper illustrates a new approach for Copy Move Forgery Detection (CMFD) built basically on deep learning. The proposed model is depending on applying (Convolution Neural Network) CNN in addition to Convolutional Long Short-Term Memory (CovLSTM) networks. This method extracts image features by a sequence number of Convolutions (CNVs) layers, ConvLSTM layers, and pooling layers then matching features and detecting copy move forgery. This model had been applied to four aboveboard available databases: MICC-F220, MICC-F2000, MICC-F600, and SATs-130. Moreover, datasets have been combined to build new datasets for all purposes of generalization testing and coping with an over-fitting problem. In addition, the results of applying ConvLSTM model only have been added to show the differences in performance between using hybrid ConvLSTM and CNN compared with using CNN only. The proposed algorithm, when using number of epoch’s equal 100, gives high accuracy reached to 100% for some datasets with lowest Testing Time (TT) time nearly 1 second for some datasets when compared with the different previous algorithms.
Lacunary ideal convergence in measure for sequences of fuzzy valued functions
Authors: Kişi Ömer
Published: March 2021

We investigate the concepts of pointwise and uniform I θ -convergence and type of convergence lying between mentioned convergence methods, that is, equi-ideally lacunary convergence of sequences of fuzzy valued functions and acquire several results. We give the lacunary ideal form of Egorov’s theorem for sequences of fuzzy valued measurable functions defined on a finite measure space ( X , M , μ ) . We also introduce the concept of I θ -convergence in measure for sequences of fuzzy valued functions and proved some significant results.
Serum Uric Acid in LRRK2 Related Parkinson’s Disease: Longitudinal Data from the PPMI Study
Authors: Bougea Anastasia , Koros Christos , Papagiannakis Nikolaos , Simitsi Athina-Maria , Prentakis Andreas , Papadimitriou Dimitra , Pachi Ioanna , Antonelou Roubina , Angelopoulou Efthalia , Beratis Ion , Bozi Maria , Papageorgiou Sokratis G. , Trapali Xenia Geronicola , Stamelou Maria , Stefanis Leonidas
Published: March 2021

Background: Previous studies have highlighted serum uric acid as a putative idiopathic Parkinson’s disease (iPD) biomarker. Only one study, so far, showed higher levels of serum uric acid in leucine-rich repeat kinase 2 (LRRK + 2) carriers compared to those who developed PD, however a longitudinal comparison between LRRK2 + PD and healthy controls (HC) has not been performed. Objective: The aim of this study was to determine whether there are longitudinal differences in serum uric acid between iPD, LRRK2 + PD and HC and their association with motor and non-motor features. Methods: Longitudinal data of uric acid of 282 de novo iPD, 144 LRRK2 + PD patients, and 195 age-matched HC were obtained from the Parkinson’s Progression Markers Initiative (PPMI) database. We also used longitudinal Montreal Cognitive Assessment (MoCA), Movement Disorder Society–Unified Parkinson’s Disease Rating Scale part III (MDS-UPDRS-III), Geriatric Depression Scale (GDS) scores, and DaTSCAN striatal binding ratios (SBRs). Results: Longitudinal uric acid measurements were significantly lower in LRRK2 + PD patients compared to HC up to 5 years follow-up. There was no significant impact or correlation of adjusted or unadjusted uric acid levels with MoCA, MDS-UPDRS III, or GDS scores, the presence of RBD or DAT-SCAN SBRs. Conclusion: LRRK2 + PD group had significantly lower uric acid concentrations compared to HC after adjusting for age, sex and baseline BMI up to 5 years follow-up. There were no significant associations between uric acid levels and indices of disease severity. These findings identify serum uric acid as a marker linked to LRRK2 + PD.
Pengaruh Profil Leukosit dan Eritrosit Sapi Bali Jantan yang Digemukkan dengan Complete Feed yang Mengandung Level Protein Kasar Berbeda
Authors: Halek Yulius Luan , Tahuk Paulus Klau , Bira Gerson Frans
Published: March 2021

Tujuan dari penelitian ini adalah untuk mengetahui profil leukosit dan eritrosit sapi bali jantan yang digemukkan dengan complete feed yang mengandung level protein kasar (PK) berbeda. Ternak yang digunakan berupa sapi bali jantan berumur 2-2,5 tahun dengan berat awal 200 kg. Ransum yang digunakan adalah complete feed yang tersusun dari bahan pakan berupa rumput alam, tepung gamal, dedak padi, jagung giling,dan bran pollard. Variabel yang diukur dalam penelitian adalah kandungan leukosit dan eritrosit. Metode yang digunakan adalah metode eksperimen menggunakan rancangan acak lengkap (RAL) dengan perlakuan sebagai berikut: T1: Tepung Rumput 27% + Tepung Gamal 10% + Jagung 34% + Pollard 15% + Dedak Padi 14%,T2: Tepung Rumput 27% + Tepung Gamal 20% + Jagung 18% + Pollard 15% + Dedak Padi 10%, dan T3: Tepung Rumput 27% + Tepung Gamal 13% + Jagung 20% + Pollard 15% + Dedak Padi 7%. Hasil penelitian menunjukkan bahwa, penggunaan complete feed dengan level PK yang berbeda tidak berpengaruh terhadap kandungan eritrosit dan leukosit sapi bali jantan. Hal ini ditunjukkan oleh kandungan eritrosit (106/μI) setiap perlakuan, yaituT1: 11,08; T2: 10,30; T3: 10,99; kandungan leukosit (103/μI) masing-masing perlakuan adalah T1: 10,51; T2: 11,59; T3:10,48. Disimpulkan bahwa pemberian complete feed dengan level PK (11%, 13%,15%) dan energi (TDN 72%) memberikan pengaruh yang sama untuk semua perlakuan dan menghasilkan kandungan eritrosit dan leukosit dalam kisaran normal.
Industry 4.0 and Logistics 4.0
Authors: Szabó Adél Anett , Bányai Ágota , Illés Béla
Published: March 2021

In these times Industry 4.0 and Logistics 4.0 has become a quite popular and trending topic amongst companies. There are market leaders who have the best knowledge and resources to use the relevant tools and technologies in their daily operation, and there are small players who has limited capabilities or only able to follow these – in all of the cases it is inevitable to get to know and utilize these technics to keep and increase competitiveness. Researches and studies has a very important role to explore these opportunities and what is more to transfer the knowledge to the participants has no access at first hand. It is specifically valid for sectors like food industry and FMCG segment where we can face with falling competition and increasing pressure caused by the higher expectations but in parallel several innovative solutions as well. This gave the reason for me to take a deep look into this case and summarize recent developments.
Peningkatan Pengetahuan Masyarakat dalam Penerapan Protokol Kesehatan melalui Edukasi Berbasis Media Online
Authors: Sudayasa I Putu , Haryati Haryati , Purnamasari Yenti , Chintia Yulin Fitri , Anwar Nur Riska , Permatasari Putri , Pebriyanti Pebriyanti
Published: March 2021

The Indonesian government has made various efforts to prevent and control COVID-19. Implementing the new normal after the COVID-19 pandemic has encouraged people to do activities as before, with the obligation to implement strict health protocols. However, the incidence of COVID-19 in Indonesia continues to increase, as is Konawe Regency as the district with the first positive case report of COVID-19 in Southeast Sulawesi and currently has six sub-districts with red zone status. This is because many people are not aware of carrying out the government's appeal in implementing health protocols. This community service aims to increase public knowledge in efforts to control COVID-19 by applying health protocols. Educational activities carried out online through online media include video conferencing in the form of a webinar through Google Meet was attended by 86 participants, live streaming on social media Facebook and Instagram, broadcasting educational videos on local TV channels, and conducting offline activities in the form of installing educational posters. Education through online media is one of the uses of internet technology, and its reach is wide and can be a solution for education during the COVID-19 pandemic. The analysis results show that education through online media effectively increases public knowledge regarding COVID-19 and the application of health protocols in the normal new era.
Pemberdayaan Kemandirian Pangan Berbasis Urban Farming di Kawasan Padat Penduduk Kota Surakarta Jawa Tengah
Authors: Barokah Umi , Rahayu Wiwit , Darsono Darsono , Marwanti Sri , Ferichani Minar , Antriyandarti Ernoiz , Ani Susi Wuri
Published: March 2021

One of the problems faced in providing food from production to urban households is limited land. This also happened in the city of Surakarta. PKK RT 03 RW XVI, Gendingan Jebres village, Jebres Subdistrict, Surakarta City is a group of women who live in densely populated settlements. The problem faced by households in fulfilling family food is dependence on purchases due to limited land for food production. One solution to overcome this problem is to develop urban agricultural activities to support food self-sufficiency. It's just that PKK members do not have knowledge of urban farming, how to apply it, and the infrastructure is limited. Therefore, this community service activity is carried out to solve this problem by conducting counseling and training on urban farming, providing assistance with production facilities in the form of seeds, seedlings, polybags, wall bags, pots, and planting media. In addition, there was also assistance in implementing urban farming for women members of the PKK. Community service activities that have been carried out have made women members of the PKK RT 03 RW XVI, Gendingan Jebres Village, Jebres subdistrict, Surakarta City have knowledge and skills related to urban farming, have urban farming infrastructure so they can implement urban farming in their environment.
Bimbingan Spiritual untuk Meningkatkan Coping Stress dalam Pandemi Covid-19 pada Pengajian ‘Aisyiyah Ranting Kereng Bengkirai
Authors: Kholisotin Lilik , Sadar Sadar
Published: March 2021

Coronavirus or severe acute respiratory syndrome coronavirus 2 is a virus that attacks the respiratory system. This disease due to viral infection is called COVID-19. The Coronavirus can cause minor disturbances to the respiratory system, severe lung infections, and death. The rapid spread of the coronavirus has caused fear, anxiety, and several other social problems in the community. Besides, the implementation of various government policies to break the chain of distribution of COVID 19, on the other hand, has had a negative impact. This community service aims to provide education to the community, especially in the teaching group Aisyiyah Kereng Bangkirai in the form of socialization and spiritual guidance to reduce anxiety and worry about Covid-19. The implementation method offered is spiritual guidance to deal with stress problems due to the Covid-19 pandemic by delivering material from an Islamic religious perspective and a psychological perspective. The results of this dedication show that there is anxiety among the community due to Covid-19 which has a psychological impact and that impact also affects the joints of community life, both socio-economic, socio-cultural, and socio-religious. Based on the results of the activities carried out, it can be concluded that community service activities can have a positive impact on society regarding the anxiety arising from the Covid-19 pandemic, as well as providing an understanding that religion is always relevant to all conditions that arise in society. Religion is not something rigid but something elastic so that it can always provide solutions to problems that arise.
Experimental study on an overhead crane passing a rail track joint
Authors: Fidrovska N. M. , Chernyshenko O. V. , Perevoznyk I. A.
Published: March 2021

Purpose. To confirm the theoretical conclusions that determining the load from the wheel impact with the joint of rails in the metal structures of overhead cranes used in the technological processes at ore mining and processing mills and integrated works and moving along the rail tracks requires that the dynamic magnification factor should take into account the trolley position. Methodology. To assess the load to which the crane metal structures are exposed the electric strain measurement method using direct bridge circuit was chosen. To calibrate the strain measurement system, the direct method was used, under which calibration is performed directly on the structure on which experimental studies will be carried out in the future. Findings. It was established that the dynamic magnification factor in the metal structure of the overhead crane had the following values when passing the last rail joints: 1.54 (with the trolley in the middle of the bridge), 2.46 (with the trolley at 0.25 of the crane span from the end beam), 3.33 (with the trolley in the extreme position). So, with the trolley being at a distance of 0.25 of the crane span from the end beam, the dynamic magnification factor is 74%, and with the trolley in the middle of the bridge, it is 46% of the dynamic magnification factor if the trolley is in its extreme position. Originality. The scientific novelty consists in the first experimental confirmation of the results obtained in the theoretical studies on the overhead crane passing the joints of the rail track with regard to the crane trolley position, which leads to changes in the stiffness of the main beam in the interval between the trolley and the final beam. Practical value. The results obtained enable calculations on the crane bridge metal structure during the design and repair of the main and end beams taking into account the value of the dynamic magnification factor, which allows increasing the reliability and durability of the crane metal structure as a whole.
Características clínicas y epidemiológicas de pacientes adultos con diagnóstico de tuberculosis extrapulmonar en el Hospital Hipólito Unanue de Tacna durante los años 2016-2018
Authors: Mamani Loza Astrid Milagros , Condori Vargas Edwin Cecilio , Mamani Loza Nayareth Nancy
Published: March 2021

Objetivo: Conocer las características clínicas y epidemiológicas de pacientes adultos con diagnóstico de tuberculosis extrapulmonar en el Hospital Hipólito Unanue de Tacna en el periodo 2016-2018. Material y métodos: Estudio observacional, descriptivo. Se incluyó a todos los pacientes mayores de 14 años con diagnóstico de tuberculosis extrapulmonar, los datos se obtuvieron de las historias clínicas, fueron procesados en el programa estadístico SPSS v24, y presentados a través de tablas con frecuencias absolutas y relativas. Resultados: De 1247 pacientes con diagnóstico de tuberculosis, la frecuencia de tuberculosis extrapulmonar fue 9,62 % (120 casos), de ellos, el 60,8 % fue hospitalizado. Los pacientes se caracterizaron principalmente por ser de sexo masculino (64,2 %), de 20 a 29 años (25,8 %), con estudios secundarios (75 %), procedentes de Tacna (74,2 %). El 68,33 % tuvo el antecedente de padecer condiciones no modificables y el 25 % tenía condiciones modificables. El 65,83 % de los casos tenía comprometido el sistema respiratorio; el 14,17 %, el sistema enteroperitoneal; el 13,33 %, el sistema nervioso central; el 9,16 %, el sistema linfático; y el 8,33 %, el sistema tegumentario. El 12,5 % presentó tuberculosis multisistémica. El 56,96 % de pacientes presentó fiebre y el 34,18 %, pérdida del peso, hiporexia y tos con expectoración. Conclusión: La pleura fue la localización más frecuente de tuberculosis extrapulmonar, el 18,3 % presentó tuberculosis pulmonar como condición no modificable, el 6,67 % VIH/SIDA y el 5 % tuvo diabetes mellitus, asma y anemia.
Neuromielitis óptica: a propósito de un caso
Authors: Del Carpio Medina Flor de María Elisa , Mamani Maquera Diego José , Mita Ticona Gerson Saúl
Published: March 2021

La neuromielitis óptica (NMO) o enfermedad de Devic, definida anteriormente por la ocurrencia de neuritis óptica (NO) y mielitis transversa (MT), se considera, actualmente, como un espectro de desórdenes autoinmunes, inflamatorios y desmielinizantes del SNC. Caso clínico: Paciente con cuadro clínico de 2 semanas de evolución, caracterizado por disminución abrupta de la agudeza visual en ambos ojos, no asociada a dolor, concomitantemente presenta disminución de la sensibilidad en región abdominal y disminución de la fuerza muscular en ambos miembros inferiores, que imposibilitan la deambulación. Resultados: El descubrimiento del autoanticuerpo AQP4 (anti-AQP4) y su asociación con la NMO, así como diferencias en presentación clínica, laboratorio, neuroimágenes, respuesta a tratamiento y pronóstico, han permitido diferenciar esta patología de la esclerosis múltiple (EM). Conclusión: El pronóstico de los pacientes con NMO es desalentador, desde la incapacidad para caminar sin ayuda, hasta la ceguera unilateral o bilateral, pueden presentarse en el 50 % de los casos.
TASAVVUF FELSEFESİNİN İMKÂNLARI BAĞLAMINDA MODERN ÇAĞDA TEVHÎD YORUMU
Authors: İZMİRLİ Betül
Published: March 2021

Tevhîd Allah’ın bir olduğunu kabul etmek mânasına gelir. O, kökeni insanın var olduğu zamana kadar uzanan bir öğretidir. Mezkûr öğreti İslâm akidesinin temelidir. Akāid, Kelâm gibi disiplinlerin başlıca teması tevhîddir. Tevhîd, Tasavvuf’un da en önemli ilkelerinden biridir. Tevhîde riâyet, sûfîler için Allah’a Elest Bezmi’nde verilmiş bir sözdür. Bu sözle onlar dünyâ-âhiret, rûh-beden, madde-mâna alanının dengesini içselleştirmişlerdir. Adaptasyonun ve uyumun vasıtası olarak tevhîd, günümüz insanına da bir rehberdir. Dünyâya, düşkünlüğün, maddeciliğin ve birtakım kaygıların karşısında, tevhîdin misyonu hayli mühimdir. Sekülerleşme ve profanlığın alabildiğine arttığı günümüzde birey, tevhîdin telkin ettiği bütünselci bakış açısını yeniden kazanmanın çabasını vermektedir. Ancak o, buhran ve sıkıntılardan tam mânasıyla kurtulamamaktadır. Çünkü kişi, âleme küllî perspektifle bakmayı sağlayan bu doktrinin bilincinde değildir. Tasavvuf felsefesinin tevhîd anlayışı bu bilinci arttırmaya yöneliktir. Sûfîlerin tevhîd yorumunun hem kendi dönemleri hem bugünün bireyi için yol gösterici niteliği bulunmaktadır. Modern çağ insanının Allah’la, kendisiyle ve âlemle ilişkisinde tevhîd, denge kurucu bir işlevi hâizdir.
Elasmobranch bycatch in US West Coast groundfish fisheries
Authors: Jannot JE , Bjorkland R , Somers KA , Mitchell T , Tuttle VJ , McVeigh J
Published: March 2021

Effective management of multispecies fisheries in large marine ecosystems is challenging. To deal with these challenges, fisheries managers are moving toward ecosystem-based fishery management (EBFM). Despite this shift, many species remain outside protective legislation or fishery management plans. How do species that fall outside of formal management structures respond to changes in fisheries management strategies? In 2011, the US West Coast Groundfish Fishery (WCGF) shifted management to an Individual Fishing Quota (IFQ) program. We used data collected by fisheries observers to examine the impact of this shift on elasmobranch catch (sharks, skates, rays). Historically, not all elasmobranchs were included in the WCGF Management Plan, making them vulnerable to fishing mortality. We grouped elasmobranchs into 8 groups based on 14 ecomorphotypes to examine relative catch within groundfish fishing sectors during the period 2002-2014. Of the 22 sharks and 18 skates and rays that these fisheries capture, 9 are listed as Near Threatened or greater on the IUCN Red List and 10 species are listed as Data Deficient by IUCN. The bycatch of 4 non-managed elasmobranch species was reduced under the IFQ program; IFQ management had no significant impact on the remaining 27 species caught by the IFQ fleet. Overall, catch of non-managed elasmobranchs was relatively low. We show that groups of ecomorphotypes co-occur within fisheries, suggesting natural management units for use in EBFM. This work helps identify gaps in monitoring and assessing the impact of management and policy on elasmobranch populations.
PERSEPSI KINERJA GURU, DITINJAU DARI PERSEPSI DUKUNGAN ORGANISASI, PERSON-ORGANIZATION FIT, DAN ORGANIZATIONAL CITIZENSHIP BEHAVIOR
Authors: Soeprijadi Fenny , Sudibjo Niko
Published: March 2021

Teachers’ performance will improve with the support of the school, compatibility between teacher as an individual with the values, goals, and characteristics of the organization. Teachers’ behavior will also contributes positively to improving performance.This study was aimed to determine the effect of perceived organizational support, person-organization fit, and organizational citizenship behavior on the performance of Kairos Gracia School teachers in West Jakarta. This research used quantitative approach and PLS-SEM method for data analysis. Data was collected by distributing questionnaires and analyzed descriptively and inferentially by conducting validity, reliability, and path analysis tests by using SmartPLS 3.2.9. software. The results showed that perceived organizational support did not have a direct positive influence on teachers performance, while person-organization fit and organizational citizenship behavior have a positive effect on performance. Perceived organization support would be positively influenced teachers’ performance when mediated by organizational citizenship behavior.

Kinerja guru akan meningkat dengan adanya dukungan dari pihak sekolah, kecocokan antara guru sebagai individu dengan nilai, tujuan, dan karakteristik organisasi Perilaku guru juga memberikan kontribusi positif terhadap peningkatan kinerja. Penelitian ini bertujuan untuk mengetahui pengaruh persepsi dukungan organisasi, person-organization fit, dan organizational citizenship behavior terhadap kinerja guru Sekolah KARIOS GRACIA di Jakarta Barat. Penelitian ini. bersifat kuantitatif. Data dikumpulkan melalui kuesioner dan dianalisis secara deskriptif dan inferensial untuk uji validitas, reliabilitas, dan analisis jalur dengan metode PLS-SEM melalui program SmartPLS 3.2.9. Hasil penelitian menunjukkan bahwa persepsi dukungan organisasi secara langsung tidak memiliki pengaruh positif terhadap kinerja guru. sedangkan person-organization fit dan organizational citizenship behavior berpengaruh positif terhadap kinerja. Persepsi dukungan organisasi akan memiliki pengaruh positif terhadap kinerja guru melalui variabel laten organizational citizenship behavior.
Optimal Operation of Isolated Micro-Grids-cluster Via Coalitional Energy Scheduling and Reserve Sharing
Authors: Qazi Hasan Saeed , Zhao Tianyang , Liu Nian , Wang Tong , Ullah Zia
Published: March 2021

Microgrids (MG) cluster are isolated from the utility grid but they have the potential to achieve better techno-economic performance by using joint energy and reserve sharing among MGs. This paper proposes a techno-economic framework for the optimal operation of isolated MGs-cluster by scheduling cooperative energy sharing and real-time reserve sharing for ancillary services based on the cooperative game theory. In the day-ahead scheduling, a coalitional sharing scheme is formulated as an adjustable robust optimization (ARO) problem to optimally schedule the energy and reserves of distributed generators (DGs) and energy storage systems (ESSs), thereby responding to the uncertainties of photovoltaic systems, wind turbines, and loads. These uncertainties are the main reason for power system imbalance which is mitigated by regulating the frequency in real-time and a dynamic droop control process is used to realize the reserves in a distributed manner. This control process is embedded into the ARO problem, which is formulated as an affine ARO problem and then transformed into a deterministic optimization problem that is solved by off-shore solvers Apart from the reduction in the operation cost, the frequency restoration can be improved jointly, resulting in the coupled techno-economic contribution of the MGs in the coalition. The contribution of each MG is quantified using shapely value, a cooperative game approach. Simulations are conducted for a case study with 4 MGs and the results demonstrate the merits of the proposed cooperative scheduling scheme.
A Substage Increase in The AJCC Classification System Improves Prognostic Prediction in Stage III Gastric Cancer With Insufficient Lymph Nodes Removed
Authors: Zhao Ri-Sheng , Liu Yi-Nan , Dai Wei-Gang , Chen Si-Le , Ye Jin-Ning , Zhai Er-Tao , Cai Shi-Rong , Chen Jian-Hui
Published: March 2021

Background

The impact of lymph nodes (LNs) removed on the survivals of patients with stage III gastric cancer, especially on that of those who undergo the adjuvant chemotherapy as a compensation for a possibly insufficient lymphadenectomy, is still unclear.

Methods

Consecutive patients (n = 488) with stage III gastric cancer under R0 curative resection followed by adjuvant chemotherapy were analyzed. The overall survival (OS) was compared between patients with insufficient LNs removed (ILNr, <16 LNs) and sufficient LNs removed (SLNr, ≥16 LNs). Performance of the prediction systems was evaluated using the Likelihood ratio χ2 test, Akaike information criterion (AIC), Harrell’s concordance index (C-index), and area under the receiver operating characteristic curves (AUC).

Results

The OS of patients were significantly longer in those with SLNr relative to those with ILNr (for stage IIIA, 68.2 vs. 43.2 months, P = 0.042; for stage IIIB, 43.7 vs. 24.9 months, P < 0.001; for stage IIIC, 23.9 vs. 8.3 months, P < 0.001; and for total stage III, 37.7 vs. 21.7 months, P < 0.001). However, the OS were similar between stage IIIA patients with ILNr and stage IIIB patients with SLNr (P = 0.928), between IIIB patients with ILNr and IIIC patients with SLNr (P = 0.962), and IIIC patients with ILNr and stage IV (P = 0.668), respectively. A substage increase in the AJCC classification system, from IIIA to IIIB, from IIIB to IIIC, and from IIIC to IV in patients with ILNr, enhanced the accuracy of prognostic prediction in patients with stage III gastric cancer compared to the current TNM system (Likelihood ratio χ2, 188.6 vs. 184.8; AIC, 4336.4 vs. 4340.6; C-index, 0.695 vs. 0.679, P = 0.002). The ROC curves revealed that the performance of prognostic prediction was better in the new prediction system (AUC = 0.699) compared with the current TNM system (AUC = 0.676).

Conclusions

ILNr (LNs <16) impairs the long-term outcomes of stage III gastric cancer underwent adjuvant chemotherapy. The status of LNs removal adds values to the current TNM system in prognostic prediction of stage III gastric cancer.
Metabolic Profiling and Gene Expression Analyses of Purple-Leaf Formation in Tea Cultivars (Camellia sinensis var. sinensis and var. assamica)
Authors: Zhu Ming-zhi , Zhou Fang , Ran Li-sha , Li Yi-long , Tan Bin , Wang Kun-bo , Huang Jian-an , Liu Zhong-hua
Published: March 2021

Purple-leaf tea cultivars are known for their specific chemical composition that greatly influences tea bioactivity and plant resistance. Some studies have tried to reveal the purple-leaf formation mechanism of tea by comparing the purple new leaves and green older leaves in the same purple-leaf tea cultivar. It has been reported that almost all structural genes involved in anthocyanin/flavonoid biosynthesis were down-regulated in purple-leaf tea cultivars when the purple new leaves become green older leaves. However, anthocyanin/flavonoid biosynthesis is also affected by the growth period of tea leaves, gradually decreasing as new tea leaves become old tea leaves. This leads to uncertainty as to whether the purple-leaf formation is attributed to the high expression of structural genes in anthocyanin/flavonoid biosynthesis. To better understand the mechanisms underlying purple-leaf formation, we analyzed the biosynthesis of three pigments (chlorophylls, carotenoids, and anthocyanins/flavonoids) by integrated metabolic and gene expression analyses in four purple-leaf tea cultivars including Camellia sinensis var. sinensis and var. assamica. Green-leaf and yellow-leaf cultivars were employed for comparison. The purple-leaf phenotype was mainly attributed to high anthocyanins and low chlorophylls. The purple-leaf phenotype led to other flavonoid changes including lowered monomeric catechin derivatives and elevated polymerized catechin derivatives. Gene expression analysis revealed that 4-coumarate: CoA ligase (4CL), anthocyanidin synthase (ANS), and UDP-glucose: flavonoid 3-O-glucosyltransferase (UFGT) genes in the anthocyanin biosynthetic pathway and the uroporphyrinogen decarboxylase (HEME) gene in the chlorophyll biosynthetic pathway were responsible for high anthocyanin and low chlorophyll, respectively. These findings provide insights into the mechanism of purple-leaf formation in tea cultivars.
The Renfrew Unified Treatment for Eating Disorders and Comorbidity: Long-Term Effects of an Evidence-Based Practice Implementation in Residential Treatment
Authors: Thompson-Brenner Heather , Singh Simar , Gardner Taylor , Brooks Gayle E. , Smith Melanie T. , Lowe Michael R. , Boswell James F.
Published: March 2021

Background:The Renfrew Unified Treatment for Eating Disorders and Comorbidity (UT) is a transdiagnostic, emotion-focused treatment adapted for use in residential group treatment. This study examined the effect of UT implementation across five years of treatment delivery.

Methods:Data were collected by questionnaire at admission, discharge (DC), and 6-month follow-up (6MFU). Patient outcomes were measured by the Eating Disorder Examination-Questionnaire, Center for Epidemiologic Studies-Depression Scale, Brief Experiential Avoidance Questionnaire (BEAQ), Anxiety Sensitivity Index, and Southampton Mindfulness Scale. Data were analyzed forN= 345 patients treated with treatment-as-usual (TAU), andN= 2,763 treated with the UT in subsequent years.

Results:Results from multilevel models demonstrated a significant interaction between implementation status (TAU vs. UT) and time, both linear and quadratic, for the depression, experiential avoidance, anxiety sensitivity, and mindfulness variables. Patients treated with the UT showed more improvement in these variables on average, as well as more rebound between DC and 6MFU. Results from multilevel models examining eating disorder outcome showed no significant difference between the TAU and UT for the full sample, but a significant three-way interaction indicated that the UT produced more improvement in the EDE-Q relative to the TAU particularly for patients who entered treatment with high levels of experiential avoidance (BEAQ score).

Conclusion:This long-term study of a transdiagnostic, evidence-based treatment in residential care for eating disorders and comorbidity suggests implementation was associated with beneficial effects on depression and emotion function outcomes, as well as eating disorder severity for patients with high levels of baseline emotion regulation problems. These effects did not appear to diminish in the 5 years following initial implementation.
The Impact of Vitamin D Level on COVID-19 Infection: Systematic Review and Meta-Analysis
Authors: Teshome Amare , Adane Aynishet , Girma Biruk , Mekonnen Zeleke A.
Published: March 2021

Background: Coronavirus disease (COVID-19) is a respiratory and systemic disorder caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or novel Coronavirus (nCoV). To date, there is no proven curative treatment for this virus; as a result, prevention remains to be the best strategy to combat coronavirus infection (COVID-19). Vitamin D deficiency (VDD) has been proposed to play a role in coronavirus infection (COVID-19). However, there is no conclusive evidence on its impact on COVID-19 infection. Therefore, the present review aimed to summarize the available evidence regarding the association between Vitamin D levels and the risk of COVID-19 infection.

Methods: A systematic literature search of databases (PUBMED/MEDLINE, Cochrane/Wiley library, Scopus, and SciELO) were conducted from May 15, 2020, to December 20, 2020. Studies that assessed the effect of vitamin D level on COVID-19/SARS-2 infection were considered for the review. The qualities of the included studies were evaluated using the JBI tools. Meta-analysis with a random-effects model was conducted and odds ratio with their 95%CI were reported. This systematic review and meta-analysis are reported according to the preferred reporting items for systematic review and meta-analysis (PRISMA) guideline.

Results: The electronic and supplementary searches for this review yielded 318 records from which, only 14 of them met the inclusion criteria. The qualitative synthesis indicated that vitamin D deficient individuals were at higher risk of COVID-19 infection as compared to vitamin D sufficient patients. The pooled analysis showed that individuals with Vitamin-D deficiency were 80% more likely to acquire COVID-19 infection as compared to those who have sufficient Vitamin D levels (OR = 1.80; 95%CI: 1.72, 1.88). Begg's test also revealed that there was no significant publication bias between the studies (P = 0.764). The subgroup analysis revealed that the risk of acquiring COVID-19 infection was relatively higher in the case-control study design (OR = 1.81).

Conclusions: In conclusion, low serum 25 (OH) Vitamin-D level was significantly associated with a higher risk of COVID-19 infection. The limited currently available data suggest that sufficient Vitamin D level in serum is associated with a significantly decreased risk of COVID-19 infection.
Four Cycles of Docetaxel-Cyclophosphamide versus Anthracycline-Taxane as Adjuvant Chemotherapy for HER2-Negative, Axillary Lymph Node Negative Breast Cancer: A Real-World Comparison of Alberta Patients Treated 2008–2012
Authors: Hannouf Malek , Batra Atul , Lupichuk Sasha
Published: March 2021

Uncertainty exists around the need to include an anthracycline if taxane-based adjuvant chemotherapy is being used for human epidermal growth factor receptor-2 (HER2) negative and axillary lymph node negative (LNN) breast cancer. We identified all patients who were diagnosed with HER2-negative, LNN breast cancer treated with docetaxel-cyclophosphamide for four cycles (DC4) or an anthracycline-taxane (AT) regimen following surgical resection in Alberta from 2008 through 2012. We used propensity score methods to match each patient treated with AT to up to four patients treated with DC4 on potentially confounding clinicopathologic and treatment variables. We compared the 10-year invasive disease free survival (iDFS), breast cancer specific-survival (BCSS) and overall survival (OS) and assessed the effect of the type of adjuvant chemotherapy on these outcomes using Cox regression. Of the 726 eligible patients, 657 (90.5%) were treated with DC4 and 69 (9.5%) were treated with AT. Matching created a group of 202 women treated with DC4 and eliminated differences in clinicopathologic and treatment factors. There was no statistically significant difference for the treatment effects of matched DC4 patients compared to the AT patients on iDFS (75.7% vs. 76.8%, p = 0.75; hazard ratio (HR) = 1.05, 95% CI = 0.65 to 1.8), BCSS (88.1% vs. 87%, p = 0.8; HR = 0.91, 95% CI = 0.42 to 1.9), or OS (87.1% vs. 86.9%, p= 0.96; HR = 0.98, 95% CI = 0.46 to 2.1). Four cycles of DC as compared with an AT regimen yielded similar 10-year iDFS, BCSS and OS amongst patients with HER2-negative, LNN breast cancer.
Evaluation of the Small Changes, Healthy Habits Pilot Program: Its Influence on Healthy Eating and Physical Activity Behaviors of Adults in Louisiana
Authors: Adhikari Praja , Gollub Elizabeth
Published: March 2021

The community-based Small Changes, Healthy Habits (SCHH) program was developed to teach skills and techniques to help adults in Louisiana make and maintain small behavioral changes in their food selection, preparation, and consumption, and in physical activity routines. The content of this four-week program included habit formation and goal setting techniques; physical activity guidance; strategies for a healthier home food environment; a grocery store tour focused on label reading for healthier food selections; basic knife and cooking skills. The program was piloted at ten sites throughout the state. A survey with 14 core items was applied before and after the program to evaluate participant acquisition of skills and behaviors associated with topic areas. A total of 47 participants provided complete data sets. Post-program, these participants reported increased confidence in preparing healthy meals at home (p = 0.04); changes in fats (p = 0.03) and salt (p = 0.01) intake; increased frequency of reading nutrition labels (32%); decreased frequency of meals eaten outside the home (Improvement Index = 0.27); and decreased time/day spent sitting (p < 0.05). These short-term results suggest that the SCHH program has potential to positively affect healthy eating and to reduce sedentary behaviors, both of which are fundamental to good health and wellness.
Narrating a Valley in Max Frisch’s Der Mensch erscheint im Holozän: Material Agency, Rain, and the Geologic Past
Authors: Kost Kiley M.
Published: March 2021

The complex narrative composition of image and text in Max Frisch’s Der Mensch erscheint im Holozän discloses entanglements between humans and nonhuman entities that impact the narrative and that demand careful consideration. The story depicts the aging protagonist’s struggle with memory loss and his careful examination of the valley’s mountain formations in fear of a landslide. In this analysis, I show that both of these threats can be read as entangled with nonhuman agents. By focusing on the material dimension of the text, two central and related shifts occur: the background element of rain becomes foregrounded in the narrative, and the natural formations of the valley that are assumed to be static are revealed to be dynamic. These shifts lead to an interpretation of Frisch’s text focused on the impacts of rain and the temporal scale of the text’s geologic dimension. Approaching the text through the lens of material ecocriticism unveils the multiple agencies at play, decenters the human, and illustrates the embodied experience of climate change.
Comment on Tsai, Y.-C., et al. Association of Stress-Induced Hyperglycemia and Diabetic Hyperglycemia with Mortality in Patients with Traumatic Brain Injury: Analysis of a Propensity Score-Matched Population. Int. J. Environ. Res. Public Health 2020, 17, 4266
Authors: Mekitarian Filho Eduardo
Published: March 2021

I read carefully the great study published by Tsai, Y [...]
Cash Flows Discounted Using a Model-Free SDF Extracted under a Yield Curve Prior
Authors: Gallant A. Ronald , Tauchen George
Published: March 2021

We developed a model-free Bayesian extraction procedure for the stochastic discount factor under a yield curve prior. Previous methods in the literature directly or indirectly use some particular parametric asset-pricing models such as with long-run risks or habits as the prior. Here, in contrast, we used no such model, but rather, we adopted a prior that enforces external information about the historically very low levels of U.S. short- and long-term interest rates. For clarity and simplicity, our data were annual time series. We used the extracted stochastic discount factor to determine the stripped cash flow risk premiums on a panel of industrial profits and consumption. Interestingly, the results align very closely with recent limited information (bounded rationality) models of the term structure of equity risk premiums, although nowhere did we use any theory on the discount factor other than its implied moment restrictions.
Outdoor Thermal Comfort Study on a District Level as Part of the Housing Programs in Abu Dhabi and Al Ain, United Arab Emirates
Authors: Bande Lindita , Adan Rahma , Young Kim , Ghazal Raghad , Jha Mukesh , Aldarmaki Amna , Aldhaheri Atmah , Alneyadi Asma , Aldhaheri Sharina , Khalifa Mira
Published: March 2021

The United Arab Emirates (UAE) has witnessed fast growth in urban development in the past four decades. A plan to build 7270 houses by 2021 has been initiated by the local authorities. Different local sustainability guidelines are being implemented, including the Public Realm Manual in Abu Dhabi. These local guidelines are tailored to consider the hot and arid climate of the UAE as well as the applied materials, the inclusion of greenery, shading devices, etc. Dubai, Abu Dhabi, and Al Ain are cities that have imposed the application of such guidelines. Additionally, the newly developed housing programs match the governmental plan. To understand the effect of these design programs on the outdoor thermal comfort (OTC), further investigations are necessary for each city. The most widely built prototype is detached villas, which result in untreated waste areas without shading or greenery. In the old local neighborhoods, Arabic houses were built next to each other to maximize the shading and to ease pedestrians’ walkability. This study aims to examine the districts where the housing programs are applied and to determine the most effective strategy to minimize the outdoor air temperatures and enhance walkability. The methodology implements the following processes in order: district analyses of the buildings as well as the externally applied materials, microclimate site measurements, ENVI-met (main software used) models of the current and future scenarios, results and recommendations. The strategies have different impacts in both cites due to the microclimate and other conditions.
Finding Myself Fast and Furiously: The Role of Agency-Communion Orientation and Self-Concept Clarity in Support for Radicalism
Authors: Choi Hyungsuk , Yoon Yeosun
Published: March 2021

The past research on radicalism is equivocal regarding the ways in which self-concept clarity shapes intentions to engage in radical behavior. Seeking to address the previous mixed findings in the literature, the present research examines how an individual’s agency-communion orientation moderates the effect of self-concept clarity on behavioral intentions for radical groups. Specifically, we propose that agency-oriented individuals show greater intentions to participate in radical groups when they experience low (vs. high) self-concept clarity, whereas communion-oriented individuals show no significant differences in their intentions to participate in radical groups across levels of self-concept clarity. A 2 (agency-communion orientation: low vs. high) × 2 (self-concept clarity: low vs. high) experimental design was used to test the hypotheses. Using gender as a proxy variable for agency-communion orientation, Study 1 shows that agency-communion orientation moderates the effect of self-concept clarity on intentions to participate in radical groups. Using chronic individual differences in agency-communion orientation, Study 2 shows that psychological entitlement mediates the interactive effect of self-concept clarity and agency-communion orientation on behavioral intentions for radical groups. Taken together, these findings support the role of agency-communion orientation and self-concept clarity in radicalism.
Analisis Technology Readiness and Acceptance Model (TRAM) Pada Penggunaan Sport Wearable Technology
Authors: Aripradono Heru Wijayanto
Published: March 2021

Pertumbuhan teknologi informasi tidak dapat dihindari terutama dalam mempengaruhi kehidupan sosial manusia saat ini. Inovasi yang dikembangkan secara tidak langsung memberikan dampak positif bagi kehidupan manusia saat ini. Wearable technology adalah salah satu teknologi yang tidak hanya memberikan banyak manfaat bagi kehidupan manusia, namun sangat membantu dalam menunjang aktivitas olahraga dan kesehatan. Wearable technology merupakan suatu teknologi komputer yang terhubung dengan koneksi internet, memiliki bentuk berupa aksesoris manusia sehari-hari yang dapat dikenakan pada tubuh mereka untuk memudahkannya dalam menerima notifikasi yang sudah terhubung dengan perangkat pintar lainnya. Pada penelitian ini akan melakukan identifkasi beberapa faktor yang mempengaruhi sudut pandang pengguna pada sports wearable technology serta untuk menginvestigasi penyebab pengadopsian konsumen pada teknologi tersebut berdasarkan teori Technology Readiness and Acceptance Model (TRAM). Penelitian ini menggunakan pendekatan kuantitatif dan variabel yang akan digunakan dalam penelitian ini adalah Positive Technology Readiness, Negative Readiness, Perceived Usefulness, Perceived Ease of Use, dan Intention to Use yang merupakan teori gabungan antara Technology Readiness and Acceptance Model (TRAM) untuk menjelaskan fenomena para pengguna terhadap penggunaan sports wearable sebagai fitness tracker mereka. Penelitian menggunakan komponen berbasis SEM dan kemudian dilakukan analisis menggunakan Partial Least Square. Penelitian ini menemukan bahwa pengguna memiliki penilaian positif (positive technology readiness) yang tinggi pada sports wearable technology melalui faktor Perceived Ease of Use (PEOU) dibandingkan dengan nilai Perceived Usefulness (PU) dalam wearable technology tersebut.
MORPHOLOGICAL AND MOLECULAR IDENTIFICATION OF ZOONOTIC TREMATODE METACERCARIAE (Haplorchis taitui) IN FRESHWATER FISH IN IRAN
Authors: Golchin Manshadi Alireza
Published: March 2021

The intestinal trematode, Haplorchis taichui (Nishigori, 1924), is an important in public health that causes infection in humans and animals especially in Asia and in parts of Africa and the Americas. Haplorchis taitui metacercariae were found in the gills of Cyprinion macrostomus (Heckel) and Capoeta barroisi persica (Karaman) collected from the Shapour River. Morphological excysted metacercariae were identified as wet mounts under a stereomicroscope. Then, the samples were subjected to molecular analysis. The result showed that 69% of examined fish (n = 30) were diagnosed infected with encysted metacercariae in gills. The mean intensity was 8.3 ± 16.9 parasites per fish. The morphometrical values agree with the findings of other studies with the small differences and polymerase chain reaction product length and nucleotide sequence analysis of 18S ribosomal deoxyribonucleic acid gene showed a similarity of over 99% between the specimens and the Haplorchis taichui (Nishigori, 1924) recorded in GenBank.
Potensi Terjadinya Persaingan Usaha Tidak Sehat pada Penggunaan Aplikasi Perdagangan Elektronik di Era Revolusi Industri 4.0
Authors: Syarief Elza , Shahrullah Rina Shahriyani , Jaya Febri , Kurniawan Jefri
Published: March 2021

Perkembangan teknologi di era industri 4.0 begitu pesat dan mempengaruhi kebiasaan masyarakat. Perubahan yang paling jelas terlihat adalah semakin banyaknya pelaku usaha yang memanfaatkan aplikasi perdagangan elektronik untuk menjalankan kegiatan usahanya, hal itu juga diikuti dengan minat konsumen yang semakin banyak bertransaksi dengan aplikasi tersebut. Penelitian ini bertujuan untuk mengetahui potensi terjadinya praktik persaingan usaha tidak sehat pada penggunaan aplikasi perdagangan elektronik saat ini, mengingat Undang-Undang Nomor 5 Tahun 1999 tentang Larangan Praktek Monopoli dan Persaingan Usaha Tidak Sehat lahir sebelum revolusi industri 4.0 terjadi. Melalui penelitian hukum normatif diketahui bahwa terdapat beberapa tindakan yang dilarang dan berpotensi terjadi dalam aplikasi perdagangan elektronik seperti oligopoli, penetapan harga, pemboikotan, oligopsoni dan perjanjian tertutup.