bluuebunny/crossref_metadata_2025 huggingface dataset:
Constructing ethno-national differentiation on the set of the TV series, Fauda
Authors: Lavie Noa , Jamal Amal
Published: June 2019

Cultural industries, television among them, are industries that exemplify harsh working conditions and precariousness. Recently, there has been greater attention paid to the specific experiences of ethnic and racial minorities in the creative industries in general and on television specifically. However, the study of minorities in television has generally focused on content analysis and not on the daily experiences of workers in the precarious television labor market itself. This paper offers an in-depth examination of the work process and conditions of ethnic–national minority (Israeli–Palestinians) versus majority creative workers (Jewish Israelis) in a television production, using observations conducted on the set of the Israeli TV series, Fauda (“ Chaos” in Arabic) as a case study. Our study’s conclusions emphasize the way groups’ experiences reproduce social hierarchies based on ethnicity, nationality, and gender.
Cardiac Pulsatility– and Respiratory-Induced Deformations of the Renal Arteries and Snorkel Stents After Snorkel Endovascular Aneurysm Sealing
Authors: Cheng Christopher P. , Suh Ga-Young , Kim John J. , Holden Andrew
Published: June 2019

Purpose: To quantify deformations of renal arteries and snorkel stents after snorkel endovascular aneurysm sealing (Sn-EVAS) resulting from cardiac pulsatility and respiration and compare these deformations to patients with untreated abdominal aortic aneurysms (AAA) and snorkel endovascular aneurysm repair (Sn-EVAR). Materials and Methods: Ten Sn-EVAS patients (mean age 75±6 years; 8 men) were scanned with cardiac-gated, respiration-resolved computed tomography angiography. From 3-dimensional geometric models, changes in renal artery and stent angulation and curvature due to cardiac pulsatility and respiration were quantified. Respiration-induced motions were compared with those of 16 previously reported untreated AAA patients and 11 Sn-EVAR patients. Results: Renal artery bending at the stent end was greater for respiratory vs cardiac influences (6°±7° vs −1°±2°, p<0.025). Respiration caused a 3-fold greater deformation on the left renal artery as compared with the right side. Maximum curvature change was higher for respiratory vs cardiac influences (0.49±0.29 vs 0.24±0.17 cm−1, p<0.025), and snorkel renal stents experienced similar maximum curvature change due to cardiac pulsatility and respiration (0.14±0.10 vs 0.19±0.09 cm−1, p=0.142). When comparing the 3 patient cohorts for respiratory-induced deformation, there was significant renal branch angulation in untreated AAAs, but not in Sn-EVAR or Sn-EVAS, and there was significant bending at the stent end in Sn-EVAR and Sn-EVAS. Maximum curvature change due to respiration was ~10-fold greater in Sn-EVAR and Sn-EVAS compared to untreated AAAs. Conclusion: The findings suggest that cardiac and respiratory influences may challenge the mechanical durability of snorkel stents of Sn-EVAS; similarly, however, respiration may be the primary culprit for tissue irritation, increasing the risk for stent-end thrombosis, especially in the left renal artery. The bending stiffness of snorkel stents in both the Sn-EVAR and Sn-EVAS cohorts damped renal branch angulation while it intensified bending of the artery distal to the snorkel stent. Understanding these device-to-artery interactions is critical as they may affect mechanical durability of branch stents and quality and durability of treatment.
Development of a clinically relevant chemoresistant mantle cell lymphoma cell culture model
Authors: He Jia , Hajj Khalid A , Knapp Christopher M , Whitehead Kathryn A
Published: June 2019

Mantle cell lymphoma is an aggressive subtype of non-Hodgkin’s lymphoma that claims the lives of tens of thousands of people every year. Although combination chemotherapy treatments such as CHOP have yielded promising outcomes in the clinic, the development of chemoresistance in patients has limited their long-term success. The lack of in vitro chemoresistance models has limited our ability to understand the mechanisms by which cells develop resistance, and thus our ability to develop novel therapeutics to overcome this issue. Here, we describe the development of a clinically relevant chemoresistant mantle cell lymphoma model using the JeKo-1 cell line. This was achieved through a stepwise treatment selection strategy using gradually increasing concentrations of CHOP. We show that resistant JeKo-1 cells display strong recovery and fast proliferation after treatment with an IC50 dose of CHOP. We also found that resistant JeKo-1 cells overexpress three oncogenes implicated in the development of mantle cell lymphoma—Cyclin D1, Mcl-1, and Bcl-2—compared to normal JeKo-1 cells. We anticipate that in vitro models such as this one will enable the discovery of new therapeutic strategies for overcoming chemoresistance and improve clinical outcomes in mantle cell lymphoma patients.

Impact statement

Mantle cell lymphoma remains one of the deadliest subtypes of non-Hodgkin’s lymphoma, in large part because patients become resistant to frontline chemotherapy. The development of strategies to treat advanced disease will be contingent upon testing in appropriate models. Most in vitro models of resistant mantle cell lymphoma are laboratory grade models that do not recapitulate the low level of chemoresistance typically observed in patients, limiting their utility. This study develops a clinically relevant in vitro model that can be used to establish the mechanisms of resistance and test new therapeutics intended to treat recurrent disease.
Sedentary Behavior and Quality of Life in Individuals With Parkinson’s Disease
Authors: Ellingson Laura D. , Zaman Andrew , Stegemöller Elizabeth L.
Published: June 2019

Background. Sedentary behavior is a growing public health concern and may have particular relevance for the Parkinson disease (PD) population. However, the influence of sedentary time on factors associated with quality of life (QOL) in PD is unknown. The primary purpose of this study was to examine relationships between sedentary behaviors and markers of PD-specific QOL. A secondary purpose was to examine relationships between physical activity behaviors and QOL. Methods. We assessed sedentary and active behaviors using objective and interview measures and examined relationships between these behaviors and a measure of PD-specific QOL in individuals with PD. Results. Results demonstrated that sedentary time was significantly related to several aspects of QOL, including perceived deficits in the domains of mobility, cognitive processing, and communication. Additionally, results showed that time spent watching television was more strongly associated with lower levels of QOL than other more engaging sedentary activities. For physical activity, relationships between objective measures and QOL were weaker and only significantly associated with mobility. Time spent doing housework was associated with lower levels of QOL, whereas time spent in recreational activity was associated with lower levels of discomfort. Discussion. These results suggest that targeting decreases in sedentary behaviors (eg, reducing time spent watching television, breaking up prolonged bouts of sedentary time) may be effective for improving QOL in individuals with PD.
A robust and accurate camera pose determination method based on geometric optimization search using Internet of Things
Authors: Wang Qi , Zhao Zhangyan , Lu Enshun , Liu Yang , Liu Licheng
Published: June 2019

We propose a robust and accurate camera pose determination method based on geometric optimization search using the Internet of Things (IoT). The central idea is to (1) obtain image information through Internet of Things technology, (2) obtain the first pose by minimizing the error function, and (3) use the geometric relationship and constraint condition to obtain the appropriate attitude angles as a new initial value for the next iteration calculation. The features of this method are as follows. First, this method can deal with a large amount of uncertain data, such as in the case of any shooting angle, in the case of any reference point, and in the case of a small number of feature points. Finally, because of using Internet of Things technology, our method can quickly complete data processing and transmission. Compared to state-of-the-art methods, the experimental results show that our approach performs well on both synthetic and real data and can be used to provide accurate and stable data for subsequent applications.
Experimental study on transmission error of space-driven gear system under large inertia load
Authors: Ma Jianfeng , Li Chao , Liu Jia , Cao Dongxing , Huang Jinfeng
Published: June 2019

There is a nonlinear disturbance problem in the operation of large inertia load space-driving mechanism, which seriously affects the normal operation of the system. A 14 degree-of-freedom nonlinear time-varying dynamic model was established for a two-stage spur gear system. The dynamic equations were solved numerically based on the Runge–Kutta method. The correctness of the dynamic model was verified through experiments. In the author’s previous research, the transmission error and dynamic response of gear system was analyzed. After the establishment of the dynamic model, a comparative analysis of the load response under different inertia was performed to illustrate the importance of studying large inertia loads. A large inertia load transmission error experimental device was set up to collect and process the transmission error data under different load inertia and different speeds. Comparing experimental results with numerical results, the correctness of the numerical model was verified, and the reasons for the differences between the two were explained. The analysis of the experimental results shows that for the transmission error of large inertia load gear transmission system, the influence of stiffness excitation on the transmission error amplitude is dominant. For the high-speed gear system, the pitch error plays a dominant role.
Effects of cladribine tablets on lymphocyte subsets in patients with multiple sclerosis: an extended analysis of surface markers
Authors: Stuve Olaf , Soelberg Soerensen Per , Leist Thomas , Giovannoni Gavin , Hyvert Yann , Damian Doris , Dangond Fernando , Boschert Ursula
Published: June 2019

Background:

Cladribine tablets 3.5 mg/kg cumulative over 2 years (CT3.5) had significant clinical/imaging effects in patients with clinically isolated syndrome (CIS; ORACLE-MS) or relapsing-remitting MS (RRMS; CLARITY and CLARITY Extension). This analysis compared the effect of cladribine tablets on the dynamics of immune cell reduction and reconstitution in ORACLE-MS, CLARITY, and CLARITY Extension during the first year of treatment (i.e. the first course of CT1.75) in patients randomized to CT3.5.

Methods:

Lymphocyte subtypes were analyzed using multiparameter flow cytometry. Changes in cell counts and relative proportions of lymphocytes were evaluated at weeks 5, 13, 24, and 48.

Results:

Across studies, consistent and comparable selective kinetics of immune cell populations occurred following the first treatment year with CT. A rapid reduction in CD16+/CD56+ cells (week 5 nadir), a more marked reduction in CD19+ B cells (week 13 nadir), and a less-pronounced effect on CD4+ (week 13 nadir) and CD8+ T cells (week 24 nadir) was shown. There was little effect on neutrophils or monocytes. Lymphocyte recovery began after treatment with CT3.5. Regarding relative proportions of naïve and memory T-cell subtypes in ORACLE-MS, the proportion of naïve-like naturally occurring T-regulatory cells (nTregs) decreased, and the proportion of memory-like nTregs increased, relative to total CD4+ T cells.

Conclusions:

CT3.5 has comparable effects on the immune systems of patients with CIS or RRMS. The pronounced reduction and recovery dynamics of CD19+ B cells and relative changes in the proportion of some immune cell subtypes may underlie the clinical effects of CT3.5.
Evidence for sex differences in morphological abnormalities in type I Chiari malformation
Authors: Houston James R , Allen Natalie J , Eppelheimer Maggie S , Bapuraj Jayapalli Rajiv , Biswas Dipankar , Allen Philip A , Vorster Sarel J , Luciano Mark G , Loth Francis
Published: June 2019

Background and purpose

Relatively little is known about the influence of individual difference variables on the presentation of macro-level brain morphology in type I Chiari malformation (CMI). The goal of the present study is to examine how case-control differences in Chiari are affected by patient sex.

Materials and methods

Patient-provided magnetic resonance images were acquired through the Chiari 1000 database. Twenty-four morphometric measurements were taken using mid-sagittal images of 104 participants (26 male CMI, 26 female CMI, 26 male controls, and 26 female controls) using internally developed and validated custom software, Morphpro. Case-control comparisons were conducted separately by sex using healthy controls matched by age and body mass index. Probability-based t-tests, effect sizes (Cohen's d), and confidence intervals were used to compare case-control differences separately by sex.

Results

Male and female case-control comparisons yielded largely the same trends of CMI-related morphometric abnormalities. Both groups yielded reductions in posterior cranial fossa (PCF) structure heights. However, there was evidence for greater PCF structure height reductions in male CMI patients as measured by Cohen's d.

Conclusions

Case-control differences indicated strong consistency in the morphometric abnormalities of CMI malformation in males and females. However, despite the higher prevalence rates of CMI in females, the results from the present study suggest that male morphometric abnormalities may be greater in magnitude. These findings also provide insight into the inconsistent findings from previous morphometric studies of CMI and emphasize the importance of controlling for individual differences when conducting case-control comparisons in CMI.
Current and emerging immunotherapeutic approaches to the treatment of multiple myeloma
Authors: Swan Dawn , Lynch Kevin , Gurney Mark , O’Dwyer Michael
Published: June 2019

Multiple myeloma (MM) has a worldwide incidence of 1–5/100,000/year. Outcomes have improved significantly in recent years following incorporation of immunomodulatory drugs and proteasome inhibitors into standard-of-care regimes. MM is profoundly immunosuppressive, enabling immune evasion, proliferation and disease progression. The role of the immune system in MM is becoming increasingly characterized and understood, and numerous therapies are under development or in routine clinical use targeting these elements of MM pathogenesis. In this review we discuss the immunosuppressive effects of MM, then the therapies targeting these defects. Specifically, we review the monoclonal and bispecific antibodies, alongside adoptive cellular therapies currently under investigation.
Microarchitectural analysis of decellularised unscarred and scarred dermis provides insight into the organisation and ultrastructure of the human skin with implications for future dermal substitute scaffold design
Authors: Khan Umair , Bayat Ardeshir
Published: June 2019

The three-dimensional spatial arrangement of dermal tissue plays a crucial role in directing cellular behaviour during wound healing. It is vital to elucidate a better understanding of the three-dimensional dermal architecture of human skin. We sought to understand the configuration in morphological structure of decellularised human dermis between unscarred skin and normotrophic scars. Skin biopsies underwent decellularisation (DNA removal = 88%). Histological analysis showed no change in gross morphology of decellularised unscarred and scarred dermis. Multiphoton and atomic force microscopies showed that collagen fibres in unscarred decellularised dermis were interwoven akin to a mesh-like structure. Collagen fibres in decellularised unscarred dermis were less stiff (mean: 2.155 ± 0.9595 MPa; p < 0.0001) with a rougher ( Rq = 16.5, Ra = 12.5, Rmax = 198; p < 0.0001) surface topography. Scarred dermis had a higher collagen volume density (papillary dermis, p < 0.0082; reticular dermis, p < 0.0332). The results demonstrate that scaffolds should exhibit a mesh-like structure with a biomimetic surface and low stiffness.
Analysis of structure and properties of antibacterial vascular patch used in abdominal aorta aneurysm surgeries
Authors: Draczyński Zbigniew , Gąsiorowski Tomasz , Kolesińska Beata , Boguń Maciej , Sujka Witold
Published: June 2019

Background:

Biocompatible materials are used for treatment of blood circulatory system diseases, especially abdominal aortic aneurysms. The most popular and often used are knitted and polymer vascular patches. The aim of this study was to optimize the manufacturing process of implantable materials, ensuring antibacterial activity useful for treating abdominal aorta aneurysms.

Methods:

The vascular patch was manufactured from Trevira® yarn. The parameters of the intermediate product and vascular patch were tested according to standard procedures.

Results:

The vascular patch, manufactured from microsilver-containing yarn, with crimps on the surface of the patch, has been found useful for treatment of abdominal aorta aneurysms. Introducing crimps on the surface of the patch resulted in reduction of water permeability and enabled cutting of the graft at various angles without fraying at the cut ends of the biomaterial. The final vascular patch was marked by a gradual release of silver within 48 hours.

Conclusions:

On the basis of the performed test, it has been demonstrated that an implantable material for the treatment of abdominal aorta aneurysms was obtained, and that it can be considered as an alternative for currently used vascular patches. The final vascular patch was marked by a gradual release of silver during the first period of incubation. The antibacterial properties of the final product were confirmed by observation of a significant reduction in the number of Staphylococcus aureus and Klebsiella pneumoniae bacterial colonies.
Restoration of an ancient temple mural by a local search algorithm of an adaptive sample block
Authors: Cao Jianfang , Li Yanfei , Zhang Qi , Cui Hongyan
Published: June 2019

Long-term influences in the external environment, including light, temperature and humidity, have caused varying degrees of damage to ancient Chinese murals. Allowing people to appreciate the original style of the murals has become important to experts, and the development of image processing and machine learning technology has allowed intelligent restoration of ancient murals. This paper proposed the adaptive sample block and local search (ASB–LS) algorithm based on the Criminisi algorithm to address the flaking deterioration of Kaihua Temple murals from the Song Dynasty. ASB–LS achieved virtual restoration of damaged areas. First, the mural’s compositional characteristics were analyzed, the structure tensor was introduced, and the data items were redefined using eigenvalues to ensure accurate transmission of the image’s structural information. Then, the data item was used to form a new priority function to improve the image filling order. Finally, the sample block size was adaptively selected by the average correlation of the structure tensor, and a local search strategy was used to improve matching efficiency, which effectively avoided mispropagation of the restored image structure and blinded search of the matching block. Experiments were performed on the Song Dynasty murals in the Kaihua Temple for two types of deterioration: flaking deterioration and artificial destruction. Compared with the Criminisi algorithm and two improved algorithms, the proposed ASB–LS algorithm had better subjective analysis and objective evaluation. Subjective visuals significantly improved and conformed to the image’s compositional characteristics, and the inpainting time efficiency improved, establishing a good foundation for restoring ancient murals.
Menin Associates With the Mitotic Spindle and Is Important for Cell Division
Authors: Sawicki Mark P , Gholkar Ankur A , Torres Jorge Z
Published: June 2019

Menin is the protein mutated in patients with multiple endocrine neoplasia type 1 (MEN1) syndrome and their corresponding sporadic tumor counterparts. We have found that menin functions in promoting proper cell division. Here, we show that menin localizes to the mitotic spindle poles and the mitotic spindle during early mitosis and to the intercellular bridge microtubules during cytokinesis in HeLa cells. In our study, menin depletion led to defects in spindle assembly and chromosome congression during early mitosis, lagging chromosomes during anaphase, defective cytokinesis, multinucleated interphase cells, and cell death. In addition, pharmacological inhibition of the menin-MLL1 interaction also led to similar cell division defects. These results indicate that menin and the menin-MLL1 interaction are important for proper cell division. These results highlight a function for menin in cell division and aid our understanding of how mutation and misregulation of menin promotes tumorigenesis.
Self-Replication of Chiral α-Amino Acids in Strecker-Type Synthesis via Asymmetric Induction and Amplification of Their Own Chiral Intermediate α-Aminonitriles
Authors: Aiba Shohei , Tanaka Yudai , Tokunaga Yuji , Kawasaki Tsuneomi
Published: June 2019

Self-replication is one of the essential characteristics of life, therefore, chemical reaction, in which biologically related chiral enantioenriched compounds can promote their own production, is an attractive challenge in broad scientific fields. Here, we found asymmetric Strecker-type synthesis, in which chiral l- and d-α-amino acids enantioselectively induced the formation and amplification of their own chiral intermediates l- and d-α-aminonitriles in solid state, respectively. Thus, after the hydrolysis of aminonitriles, enantioenriched amino acids with the same structure and the same absolute configuration as that of the original compounds could be replicatively produced with improvement of enantiomeric excess. Following our first report on the replication of α-(p-tolyl)glycine, here we found that the enantiomer of α-(1-naphthyl)glycine and α-(o-tolyl)glycine can also replicatively multiply in the Strecker-type synthesis via the amplification of the corresponding aminonitriles. From the viewpoint of the absolute asymmetric Strecker-type amino acid synthesis, spontaneous formation, amplification and multiplication, i.e., enantioselective reactive crystallization of α-aminonitriles will be discussed.
Distribution of Toxoplasma gondii IgM and IgG antibody seropositivity among age groups and gestational periods in pregnant women
Authors: Sadiqui Shahida , Shah Syed Rafiq Hussain , Almugadam Babiker Saad , Shakeela Qismat , Ahmad Shehzad
Published: June 2019

Background: Toxoplasmosis is a globally distributed parasitic disease. The present study aimed to estimate the prevalence and geographic distribution of toxoplasmosis as well as determine the percentage of toxoplasmosis-associated IgM and IgG seropositivity among different age groups. In addition, it aimed to estimate the proportion of toxoplasma IgM seropositivity among pregnancy trimesters.

Methods: A total of 500 pregnant women were included in this study. From each participant, a 5-ml venous blood sample was collected and centrifuged to obtain serum that was tested for Toxoplasma gondii IgM and IgG antibodies using immunochromatographic testing and ELISA.

Results: The overall seroprevalence of toxoplasmosis was 24.8%. Out of the total of 500 participants, only 8% had a serological marker of acute toxoplasmosis). There is a statistically significant difference in the seroprevalence of disease among the study areas. Amongst positive cases of every trimester, 54.34% of first trimester positive cases had a serologic marker for acute toxoplasmosis. 

Conclusions: In this study, there is a high prevalence of toxoplasmosis. Therefore, it is necessary to test every pregnant woman for toxoplasmosis and distinguish the type of infection, as well as the conduction of public health education programs to generate the awareness.
Characterisation of blood vessels used for coronary artery bypass surgery
Authors: Garnizone Marika , Vārtiņa Edīte , Pilmane Māra
Published: June 2019

Saphenous veins are commonly used as coronary artery bypass grafts. Therefore, it is important to understand the vein wall morphology used for the bypass grafts.

Methods. Ten specimens of saphenous veins were obtained from 10 patients admitted to the Heart Surgery Centre of P. Stradiņš Clinical University Hospital for coronary artery bypass surgery and a histopathological study was conducted. The slides were processed for histological routine and immunohistochemical staining with following markers: endothelin (ET), metallomembranoproteinase 2 (MMP2), tissue inhibitor of metalloproteinase 2 (TIMP2), transforming growth factor beta (TGF β), hepatocyte growth factor (HGF), vascular endothelial growth factor (VEGF), protein gene product 9.5 (PGP9.5), vascular cell adhesion molecule (VCAM), intercellular adhesion molecule (ICAM). For the analysis of the positive structures detected by immunohistochemistry, a semiquantitative evaluation method was used.

Results. Normal histoarchitecture of the vein wall was evaluated by routine staining. Moderate positive endothelin containing endothelial cells and moderate to numerous positive VEGF cells were found on small blood vessels. Moderate positive MMP2 structures and variable – mainly moderate to numerous positive TIMP structures – were found in vein wall. Positive structures were evaluated as equal with both MMP2 and TIMP, with one exception where MMP2 positive structures were evaluated as moderate, but TIMP positive structures as few. All specimens were rich in TGFβ, VCAM and ICAM cells. Abundance of VCAM and ICAM positive endothelial cells was also found. Few HGF positive structures were found in tunica intima and few PGP9.5 positive nerve fibres in tunica adventitia.

Conclusions. Rich expression of TGFβ, VCAM, ICAM is characteristic for saphenous vein. A number of VEGF, MMP and TIMP positive cells found in saphenous vein wall indicates a presence of tissue remodelling and ischemia, while low number of HGF positive cells shows its lesser involvement in homeostasis regulation.
Characterization of morphology in healthy, traumatized and aged knee meniscus of different species: A pilot study
Authors: Podļesnaja Marija , Pilmane Mara , Ciems Modris
Published: June 2019

Meniscus is a fibrocartilaginous anatomical structure that realizes complicated biomechanical functions in the knee joint. However, no comparative morphology studies have been done on different species and conditions regarding the meniscus. Thus, the aim of our pilot study was to compare the morphology of traumatized and aged human and healthy deer meniscus to reveal the tissue ground, growth, degeneration, cell death and inflammation factors.

The study included surgery materials from one deer and two humans. Biotin-streptavidin immunohistochemistry was performed for detection of tissue TGFβ1, MMP2, MMP9, collagen I, caspase, Il-1, Il-6, Il-10. The results were evaluated semiquantitatively. An abundant number of Collagen I positive cells were detected in the disordered human meniscus but not in the deer one. TGFβ1 was seen in numerous to abundant number of cells in all the three cases. MMPs and caspase were distributed with numerous to abundant cells in both human and deer meniscus. Numerous to abundant cells of traumatized and aged human menisci showed IL-1 and IL-6, while the deer meniscus demonstrated cytokine expression in a moderate number of cells only in limited zones. The traumatized human meniscus possessed an abundant number of IL-10 positive cells, while the deer and the aged human meniscus showed mainly a moderate number of IL-10 cells with some elevation of cytokine in superficial and deepest layers of the meniscus.
In memoriam Emeritus Professor Arne Lepp: A life dedicated to medicine
Authors: Pärnsalu Liina , Liigant Aade , Kokk Kersti , Põldoja Elle
Published: June 2019

28 November 1928 − 23 October 2018
Process, Religion, and Society
Authors: Cobb John B
Published: June 2019

"NO ABSTRACT"
God-World Polarity: A Paradigm for Reconciliation
Authors: Thottakara, CMI Augustine
Published: June 2019

"NO ABSTRACT"
Whitehead,Cosmology And Civilization
Authors: Greene Hermen F
Published: June 2019

No Abstract
Harmony between Spiritual and Real World: Teachers' Professional State under the Vision of Process Philosophy
Authors: Shi-zhou Lou , Lizheng Zhang
Published: June 2019

"NO ABSTRACT"
Whitehead's Brain Science of Emotions
Authors: Thandeka Thandeka
Published: June 2019

"NO ABSTRACT"
Whitehead and Particle -Wave Duality: A Critical Study from the Perspective of System Philosophy
Authors: George Luke
Published: June 2019

"NO ABSTRACT"
Vision of Organic Whole: Process Thought and Siddha Cult
Authors: Peter Vallabadoss John
Published: June 2019

"NO ABSTRACT"
Supporting families with food allergy in children
Authors: Noakes Amy
Published: June 2019

Health visitors are encouraged to provide supportive visits for parents of children with a diagnosed or suspected food allergy, says Amy Noakes
Language and literacy development in the early years
Authors: Hancock David
Published: June 2019

In 2018, the BBC announced a new education strategy to help address language and communication delays in children starting primary school. David Hancock investigates how the initiative and others across England are working to tackle the issue
All about … imaginary friends
Authors: Russell Meredith Jones
Published: June 2019

Why do some children have imaginary friends, when do they have them and what purpose do they perform, asks Meredith Jones Russell
Free to choose
Authors: Vollans Caroline
Published: June 2019

How can settings ensure that boys and girls are given equal and unbiased opportunity to take part in all activities? Caroline Vollans reports on the Gender Action approach
¿QUÉ COMPETENCIAS DEMANDAN LOS CENTROS DE SECUNDARIA AL PROFESORADO NOVEL EN CATALUÑA?
Authors: Freixa Niella Montserrat , Llanes Ordoñez Juan , Venceslao Pueyo Marta , Corti Franciele
Published: June 2019

INTRODUCCIÓN. Esta investigación tiene como objetivo indagar en la percepción que tienen los ocupadores del ámbito de la educación secundaria sobre las competencias del profesorado recién graduado, con la finalidad de articular las demandas formativas de los centros con la formación universitaria, al tiempo que incidir en la mejora de esta última. MÉTODO. El trabajo se ha llevado a cabo a partir del análisis de la base de datos del estudio Ocupadors a l’àmbitd’Ensenyament, realizado a finales de 2015 por la AQU. Fueron encuestados 281 centros educativos de Cataluña, de los cuales nos centraremos en los 69 centros de enseñanza secundaria y, especialmente, en los 34 centros que incorporaron docentes graduados recientemente. RESULTADOS. La técnica estadística multivariante del Análisis Factorial Exploratorio ha permitido, por una parte, identificar las competencias con más peso en el modelo factorial y, por otra, agrupar las competencias en factores independientes entre ellos. El modelo factorial resultante está compuesto por cuatro dimensiones que han sido analizadas según su importancia, satisfacción y margen de mejora: (1) competencias instrumentales y técnicas; (2) competencias pedagógicas; (3) competencias para la interdisciplinariedad, y (4) competencias sistémicas. DISCUSIÓN. Los resultados ponen de manifiesto que tanto las pedagógicas como las sistémicas son las competencias que presentan un mayor margen de mejora en la formación inicial. Otro resultado reseñable es la especial importancia que atribuyen a las competencias para la interdisciplinaridad. Ambas cuestiones nos invitan a reflexionar sobre el perfil del docente de secundaria —disciplinar o polivalente—, así como con la formación en competencias de este profesorado.
POTENCIANDO LA COORDINACIÓN PEDAGÓGICA A TRAVÉS DEL LIDERAZGO DE LOS MANDOS MEDIOS EN EDUCACIÓN SECUNDARIA. REVISIÓN SISTEMÁTICA
Authors: García-Martínez Inmaculada , Martín-Romera Ana
Published: June 2019

INTRODUCCIÓN. En la actualidad se apuesta por modalidades distribuidas de liderazgo como garante de mejora escolar. Su implantación requiere que la dirección como líder formal del centro inicie procesos de cambio internos, que redunden tanto en la organización como en la cultura escolar. MÉTODO. El presente artículo se corresponde con una revisión sistemática referida a modalidades distribuidas de liderazgo, encabezadas por los líderes medios (fundamentalmente jefes de departamento o coordinadores pedagógicos). Para ello, se siguieron los parámetros promovidos por la declaración PRISMA, para asegurar la cientificidad a lo largo de todo el proceso. Tras la revisión realizada en las bases de datos Web of Science y Scopus, aparecieron 18 artículos. RESULTADOS. Entre los resultados hallados se encontró que las figuras intermedias de la organización educativa tienen una capacidad real de liderazgo cuando se promueve una cultura de colaboración en el centro y se establecen unas metas compartidas. Asimismo, se establece una relación positiva entre una cultura de colaboración y una mejora del desarrollo profesional del profesorado, que unido da lugar a mejoras en el rendimiento académico del alumnado. DISCUSIÓN. La principal conclusión de esta investigación es la importancia de incentivar un ambiente de colaboración y confianza en el centro educativo, mediado por una buena gestión de la dirección en esta encrucijada. Igualmente, es importante que exista una buena disposición del profesorado para trabajar con sus compañeros e implicarse en un proyecto común, dirigido a la mejora. Este planteamiento de la escuela, precisa de cambios organizativos y culturales, que afectan a la labor docente y a su identidad profesional.
Participatory Research through Gastronomy Design: A designerly move towards more playful gastronomy
Authors: Wilde Danielle , Bertran Ferran Altarriba
Published: June 2019

Socialization, eating and play are core activities that make us human. While they are often brought together, play theory suggests that their combination has unexplored potential in the context of gastronomy. Our research also indicates that a chef’s desire to control the meal may be a key impediment to developing dining experiences in which the diner’s playful engagement impacts taste, texture and flavour combination. We investigate if combining participatory research through design and play theory might better situate chefs to diversify their approach to playful gastronomy. Using experimental design methods, we interviewed a chef, a maître d’, a professional gastronomist, two food enthusiasts and a novice, to identify overlooked opportunities to extend play in gastronomy. We then conducted a series of dinners – designed with and for experts, enthusiasts and novices – to explore these opportunities, and tested the resulting method through a workshop with student chefs and game designers. We present the method: Participatory Research through Gastronomy Design (PRGD), using the case of its development to explicate its characteristics. Our research suggests that PRGD supports the design of playful gastronomic experiences that appeal to a range of diners, affords exploration of play’s impact on social dynamics and can productively inform concrete design choices. It also – crucially – supports chefs to partially transfer control of how a meal unfolds, without diluting their sense of controlling the overall experience. PRGD thus addresses a key impediment to extending play in gastronomy. Gastronomy that responds to diners’ needs and desires for play are currently limited. We propose PRGD as an exciting – and viable – approach to address this limitation.
Semantic and Lexical Text Analyzer
Authors: Servet Marcos , Martín David , Pérez Daniel
Published: June 2019

A multi-agent systems is described that analyzes texts from two points of view: on the one hand in a lexical and on the other in a semantic way. The main purpose of the system is the efficient processing of the inputted text in order to analyzing it, and as a result, outputting it in the right way. That means that after analyzing each phrase of the imputed text, the main agent will delete each wrong phrase. Agents will exchange messages trying to stably which phrase is correct or incorrect. The system will not only remove wrong phrases, it will also make a list with all the removed ones and the reasons that made the main agent discard them so the person that inputted the text can know why those phrases were in a wrong way.
Exploiting Asynchrony in Multi-agent Con-sensus to Change the Agreement Point
Authors: Pellitero Diego , Sánchez David , Hernández Mario , Serrano Álvaro
Published: June 2019

Reaching agreement by consensus is fundamental to the operation of distributed systems, such as sensor networks, social networks or multi-robot networks. In real systems, the resource limitations available to individual agents and communication delays typically result in asynchronous control models of discreet time for consensus. In this paper, we model the problem where a set of agents arrive at a consensus on the value of a variable of interest, being guided by one of them.
The medical relevance of Spirometra tapeworm infection in Indonesian Bronzeback snakes (Dendrelaphis pictus): A neglected zoonotic disease
Authors: Yudhana Aditya , Praja Ratih Novita , Supriyanto Arif
Published: June 2019

Aim: Spirometra parasites cause sparganosis, a zoonotic disease, especially in reptiles and humans. This study aimed to report on the prevalence and effects of Spirometra parasites infection on public health and provide a scientific foundation for its prevention. Materials and Methods: A total of 378 living Indonesian wild-caught and captive-bred Bronzeback snakes (Dendrelaphis pictus) were selected. The snakes were euthanized using ethyl ether anesthesia before checking for Spirometra parasites. The numbers of Spirometra located in the muscle tissue, subcutaneous tissue, and coelom (including the viscera) were each counted to investigate the distribution of Spirometra inside the snake body cavity. Results: The total prevalence in the sample was 50.85%. The prevalence values in wild-caught and captive-bred snakes were 70.7% and 48.7%, respectively. More than half (56.6%) of the Spirometra parasites were located in the muscular tissue, while 29.5% were in the subcutaneous tissue and 13.8% were in the coelomic cavity. Conclusion: Wild-caught Indonesian Bronzeback snakes, which are sold as food in markets, and captive-bred snakes, which are collected as exotic pets in Indonesia, have similar opportunities to transmit the Spirometra parasite and cause global health problems due to their high prevalence.
PRODUÇÃO DO ESPAÇO URBANO E A AÇÃO DO ESTADO
Authors: Celestino Paula Leilane Oliveira
Published: June 2019

O presente trabalho tem por objetivo estabelecer uma análise acerca de que forma ou quais princípios são utilizados pelo Estado no processo de intervenção em assentamentos precários por meio de ações estratégicas e quais são os reflexos na produção do espaço urbano. Dessa maneira, propõe-se uma discussão sobre a ação do Estado através do Programa de Aceleração do Crescimento – PAC (2007-2010), que além de representar um importante avanço em termos de políticas públicas, também constitui-se em uma retomada das discussões de áreas habitacionais precárias. Desse modo, é mister ressaltar os mecanismos utilizados, pois além de principal agente produtor do espaço urbano, o Estado atua de acordo com interesses capitalistas, o que se torna evidente com as desigualdades socioespaciais. Para a realização da pesquisa a metodologia utilizada priorizou uma revisão teórico-conceitual e pesquisa documental.Espaço Urbano
EXPRESSÕES E SIGNIFICADOS DO CIRCUITO INFERIOR DA ECONOMIA URBANA DE IMPERATRIZ
Authors: Lima Bruno , Sousa Jailson de Macedo
Published: June 2019

Diante do reconhecimento da importância assumida pelo segmento terciário de Imperatriz e ascaracterísticas e significados do circuito inferior da economia urbana de deste município,buscamos neste estudo, entender as suas expressões para economia imperatrizense. Dentre osmotivos ressaltados para a realização da presente pesquisa, está a necessidade de reconheceras causas e os fatores que determinaram o surgimento do setor informal da economia. E aindasaber quais são as contribuições deste segmento para a economia da cidade de Imperatriz, econsequentemente, entender quais são os possíveis problemas gerados por ele à cidade.Buscamos entender a dinâmica do circuito inferior e do superior da economia urbana, poisentende-se que para o circuito inferior existir é necessário que haja um circuito superior. Esteprimeiro, em muitos momentos, vai precisar de algumas manutenções que são encontradas nosegundo circuito. A presente pesquisa objetiva ainda, conhecer o público alvo consumidor docircuito inferior da economia urbana, quem são e porque preferem consumir os produtosofertados por este segmento.
Pertumbuhan dan produksi tanaman kailan (Brassica oleracea) akibat pemberian mulsa jerami padi dengan takaran yang berbeda
Authors: Setiyaningrum Alvianisa Anjanuari , Darmawati Adriani , Budiyanto Susilo
Published: June 2019

ABSTRACT  The objective of this research was to examine the effect and quantity of rice straw mulch on the growth and production of kailan. This research was conducted inAspakusa Makmur Farms Association, Teras, Boyolali and Laboratory of Ecology and Plant Production, Faculty of Animal and Agricultural Sciences, Diponegoro University, Semarangfrom January 24th to March24th 2018. The research was assigned in completely randomized monofactor design with the factor was M0: control, M1: 2 ton/ha, M2: 4 ton/ha, M3: 6 ton/ha and M4: 8 ton/ha. Parameters observed were plant height, number of leaves, soil and temperature, plant and root wet weight, plant and root dry weight and total chlorophyll content.The results showed thatmulch treatment with a dose of 6 tons/ha was able to increase the yield of leaves, root dry weight and total chlorophyll content but did not increase crop yields, soil and temperature, plant and root wet weight, plant dry weight Keyword: Kailan, Mulch, Rice straw ABSTRAK  Penelitian bertujuan untuk mengkaji pengaruh dan takaran mulsa jerami padi terhadap pertumbuhan dan produksi tanaman kailan. Penelitian dilakukan pada tanggal24 Januari 2018 – 24 Maret 2018 di Lahan pertanian Asosiasi Aspakusa Makmur Kecamatan Teras Kabupaten Boyolali dan Laboratorium Ekologi dan Produksi Tanaman, Fakultas Peternakan dan Pertanian, Universitas Diponegoro, Semarang. Penelitian disusun dengan rancangan acak lengkap monofaktor dengan perlakuan M0: kontrol, M1: jerami padi 2 ton/ha, M2: jerami padi 4 ton/ha, M3: jerami padi 6 ton/ha dan M4: jerami padi 8 ton/ha. Parameter yang diamati adalah tinggi tanaman, jumlah daun, kelembaban dan suhu tanah, berat basah tanaman dan akar, berat kering tanaman dan akar dan kandungan klorofil total. Hasil penelitian menunjukkan bahwa Perlakuan mulsa dengan takaran 6 ton/ha mampu meningkatkan hasil jumlah daun, berat kering akar dan kandungan klorofil total tetapi tidak meningkatkan hasil tinggi tanaman, kelembaban dan suhu tanah, berat basah tanaman dan akar, berat kering tanaman Kata kunci: kailan, mulsa, jerami padi
Morpho-anatomical evaluation of hypoglycaemic medicinal plants
Authors: Duarte Gondim Roberta Sabrine , Ribeiro e Silva Isolda , Freitas Soares Filho Flávio , Silva Araújo Luz Tássio Rômulo , Lopes de Castro Tázia , Barreto Serra Mariana , Assunção Barroso Wermerson , Machado Vilanova Crisálida
Published: June 2019

This study aimed to morpho-anatomical characterize leaves of plants with hypoglycemic effect used by the Maracanã community of São Luís-MA. It was selected two vegetal species with lack of morpho-anatomical studies, which were Cissus verticillata (L.) Nicolson & C. E. Jarvis (Vitaceae) and Caesalpinia ferrea Mart. ex. Tul. var. leiostachya Benth (Leguminoceae). The botanic material was collected in the Dom Delgado University City, UFMA. It was realized paradermic and transverse sections free hand with blade support, using astra blue and basic fuchsin as colorants. The laminas were observed and photographed in optic microscopic. Cissus verticillata presented simple and opposite leaves, with membranous consistency, serrated margin, and acute top and cordate base. The mesophyll is dorsiventral composed by palisade and spongy parenchyma. Central rib with presence of reserve parenchyma and angular chollenchyma with some points of ring deposition. Caesalpinia ferrea presented smooth and simple leaves, uniseriate epidermis, curled cuticles and presence of stomata on both sides. Central rib with fundamental parenchyma composed by spherical cells and angular chollenchyma. The reported morphoanatomic characters of C. verticillata and C. ferrea leaves contribute to the identification and characterization of the quality of these vegetables, improving knowledge verification of plant species authenticity.
Pricing, Signalling, and Sorting with Frictions
Authors: Godenhielm Mats , Kultti Klaus , Virkola Tuomo
Published: June 2019

We analyse signalling and sorting in a market with frictions and private information. Buyers are heterogeneous, the sellers choose what quality to produce and post prices. Buyers do not observe quality, but infer it from prices. In equilibrium high-quality sellers signal quality with a price that is higher than under perfect information. Compared to the outcome under perfect information the higher price has two effects. First, it makes production of high-quality goods more attractive increasing its supply. Second, it makes high-valuation buyers worse-off, directing part of them to low-quality sellers. We determine which effect dominates; whether too many or too few sellers produce high quality. We also show that the prices of both high- and low-quality goods are higher, and the sellers do better and the buyers worse under private information. In addition, we show that an increase in the production cost of high quality may lead to higher profits and prices.
Optimization of a Computer Simulated Styrene Plant by Surface Response and Environmental Impact Evaluation
Authors: Vieira Goncalves Ricardo , Teixeira Gustavo , Torres Alice , de Assis Adilson Jose
Published: June 2019

Computer Aided Design of Chemical Process is now a well established eld in the design of new process as well as in the optimization, revamp and retrot of existing ones. The use of powerful process simulators available today allows the process engineer to simulate even an entire process, but the majority of process simulators have only classical unit operations. So, if the process has a non-classical unit operation it needs to be simulated using a suitable computer language and further to be linked to the simulator. In this paper we addressed the problem of including a new unit operation in a process simulator and how to use the virtual plant to optimize and to evaluate the environmental impact of a chemical process. We used the free chemical process simulator COCO to simulate two styrene process production plant. The firrst one uses as a reactor a conventional PFR that is available in the simulator. The second plant uses a membrane reactor that was simulated using the software Scilab that was embedded in COCO simulator by using the CAPE-OPEN protocol. Then, we used both virtual plants to develop meta-models of the processes by using experimental design and surface responses. These empirical models were used after to optimize the plants and the results shown that it is possible to increase the styrene productivity up to 27.32 kmol/h using a PFR reactor and up to 30.56 kmol/h using a membrane reactor. Finally, we calculated the Potential of Environmental Impact (PEI) for each process using the WAR algorithm and we shown that both processes have PEI very similar. Therefore, the route that uses membrane reactor has an advantage over the route that uses PFR reactor since it allows to obtain higher styrene productivities.