bluuebunny/crossref_metadata_2025 huggingface dataset:
PSYCHOLOGICAL ASPECTS OF ADAPTATION OF THE HEALTHY HUMAN ORGANISM TO SIMULATED SPACEFLIGHT FACTORS IN AN EXPERIMENT WITH 21-DAY DRY IMMERSION
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Zhuravleva T.V. , Loguinov V.I. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: March 2024

The 21-d dry immersion study with participation of 8 male volunteers at the age of 25 to 33 years included investigations of the psychological aspects of adaptation to simulated spaceflight factors. Psychological testing 14 days prior to DI and on day 21 of the study was performed using the multilevel adaptivity inventory (А.G. Maklakova and S.V. Chermianina), the inventory of mental activity, interests, affective tone, strain and comfort (L.A. Kurgansky and Т.А. Nemchina), well-being in extreme conditions inventory (А. Volkova and N.E. Vodopianova) and situation-adaptable subjective vitality scale (R. Rayan and S. Frederick, apecialized by L.A. Aleksandrova). Participants in the study adapted successfully to the conditions as could be deduced from stability of their personal adaptation potential. At the end of the study the participants were noted to be more neurotic, demonstrated symptoms of autonomic regulation imbalance, disorders in the sleep wakefulness cycles, psychological discomfort and reduction of the energy potential. These changes witnessed to a moderate stress reaction to the DI conditions.
EFFECT OFS HORT-TERM ISOLATION AND CONFINEMENT IN A SMALL CHAMBER ON SUBCLINICAL REACTIVATION OF LATENT VIRAL AND BACTERIAL PATHOGENES IN HUMANS
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Shulguina S.M. , Rykova M.P. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Kutko O.V. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Shmarov V.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Antropova E.N. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Zhirova E.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Orlova K.D. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Sadova A.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Vlasova D.D. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Ponomarev S.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: March 2024

The paper presents data of the investigations of subclinical reactivation of 7 human herpes viruses and bacteria Mycoplasmahominis, Ureaplasmaurealiticum and Chlamydiatrachomatis from 6 participants in a 14-day isolation study conducted in a small chamber with controlled environment. Purpose of analysis was to establish correlations between DNAs of latent viral and bacterial pathogens in bio-liquids of organism and indices of the natural and adaptive immune system. It was determined that short-term isolation in a small chamber may provoke reactivation of latent pathogens both of the viral and bacterial nature. The events can be triggered by changes in the immune status and appear in consequence of depressed immunological control of latent infections. Dynamics of the latent infections lytic cycle in the course of the study demonstrated a high degree of individual variability.
INVESTIGATION OF THE EFFECT OF PROPHYLATIC CONSUMPTION OF A STREPTOCOCCUS SALIVARIUS-BASED AUTOPROBIOTIC ON ORAL MICROBIOTA OF PARTICIPANTS IN ISOLATION STUDY «SIRIUS-2021»
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Ilyin V.K. , Solovieva Z.O. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Nosovsky А.М. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Rykova M.P. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Sheblaeva A.S. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Sheblaev M.V. ,   Lomonosov Moscow State University, Lovtsevich S.M. ,   Institute of Analytical Toxicology, Moscow, Kraeva L.A. ,   Saint-Petersburg Pasteur Institute, Guizinger О.А. ,   Peoples' Friendship University of Russia named after Patrice Lumumba, Medical Institute, Moscow
Published: March 2024

Effect of an autologous preparation based on Streptococcus salivarius (S. salivarius) on oral cavity microbiota was investigated in participants of 8-month isolation study SIRIUS-2021 with the purpose of developing programs of preventing immunomicrobiological disorders. We investigated microbiota qualitative and quantitative dynamics, microbiological changes before and after consumption of the S. salivarius preparation using a bacteriologic technique, MALDI-TOF mass spectrometry, and microbial markers mass-spectrometry. Concentrations of secretion immunoglobulin А (sIgA) and IL-8, IL-10 cytokines in oral liquid were determined with the immune-enzyme assay. It was found that the S. Salivarius-based autologous preparation had a favorable effect on the mouth microbiocenosis in all the participants in the study.
Dwaj ludzie z lustrem. Metafory fotografii i fotograficzne motywy w etiudach Romana Polańskiego
Authors: Szczypiorska-Chrzanowska Magdalena
Published: March 2024

Two Men and a Wardrobe: Photographic Motifs and Metaphors in Roman Polanski’s Short Films
This paper attempts to explore the photographic metaphors (Bernd Stiegler’s categories) and motifs drawing on photographic techniques and practices in three short films directed by Roman Polanski while still a student (Two Men and a Wardrobe, Teeth Smile, Murder). Metaphors and motifs originating in the technical, practical, mythopoetic, and anthropologic aspect of photography—e.g. mirror, doubling, doppelgänger, shade, voyeurism, murder, mortification/vivification—used in Polanski’s early film narratives refer to copying vs. creating, reproducing a fragment of the world vs. developing it anew, exploring “reality” vs. illusion, “truth” vs. imagination, optics vs. metaphysics, and produce an autonomous space of meanings and possible interpretations. The theoretical framework of the analysis is provided by selected threads in the theory and philosophy of photography drawn from the works of Bernd Stiegler, Roland Barthes, Edgar Morin, Susan Sontag, John Szarkowski, and Edouard Pontremoli.
Polański i symulacje. Na marginesie tekstu Ewy Mazierskiej "Roman Polański (i inni) przed sądem"
Authors: Tomczyk-Jarzyna Izabela
Published: March 2024

Polanski and Simulations: A Few Remarks on Ewa Mazierska’s essay “Roman Polanski (and Others) on Trial”
The text is a commentary on the article by Ewa Mazierska “Roman Polanski (and Others) on Trial.” Using Baudrillard’s concept of simulation, the author shows that discussions on Polanski’s personal conduct do not lead to finding meaning.
Synthetic Update on Antimicrobial Potential of Novel Pyrazole Derivatives: A Review
Authors: Singh Sucheta , Tahlan Sumit , Singh Kuldeep , Verma Prabhakar Kumar
Published: March 2024

Heterocyclic compounds containing nitrogen and their derivatives have been a
rich source of medicines. Pyrazole, a five-membered ring structure, offers a variety of functionalities
as well as stereo-chemical complexity. Studies conducted over the past 10 years
revealed that an increasing amount of research has been performed on different pyrazole
derivatives and their physiological and pharmacological activities. The objective of these
studies is to uncover the full potential of pyrazole derivatives by elucidating the many druglike
properties and their link between the structure and mode of action. Here, we discuss
different ways of synthesizing pyrazole derivatives. Due to recent advances in synthetic
medicinal chemistry, this class of compounds can be readily developed and becomes a viable
target for the discovery of novel drugs.
Effects of Mesenchymal Stem Cell-conditioned Media with Natural Immunomodulatory Agent Resveratrol on Type 1 Diabetes
Authors: Abhale Krushna , Addepalli Veeranjaneyulu , Desai Shivani , Sanap Avinash , Bhonde Ramesh
Published: March 2024

Background:

Type 1 diabetes mellitus (T1DM) is a condition marked by elevated
blood sugar levels and primarily recognized by the destruction of beta cells caused by an autoimmune
attack, which is a significant characteristic of T1DM. Recent studies have demonstrated the
regenerative potential of conditioned medium therapy. In light of this, the current research sought
to assess the impact of Mesenchymal Stem Cell conditioned media (CM) and CM with resveratrol
(CM+ Resveratrol) on the management of T1DM in Swiss albino mice. By leveraging and modifying
existing conditioned medium therapy, this study aims to evaluate its effectiveness in treating
T1DM.

Materials & Methods:

Diabetes was induced in animals using the diabetes-inducing agent streptozotocin
(STZ). The animals were then divided into five groups: Normal control, Disease Control,
Resveratrol, Condition Media, and CM + Resveratrol. Treatments were given to the animals accordingly.
The study period was 28 days. During this time, the animals were monitored for foodwater
intake twice a week, blood glucose levels, and body weight. At the conclusion of the 28-day
study period, biochemical estimations were performed for serum insulin levels, C-peptide levels,
anti-inflammatory cytokines levels and pro-inflammatory cytokines levels. Additionally, histopathology
of the pancreas was performed.

Results:

The test groups showed a significant decrease in blood glucose levels, an increase in Cpeptide
levels, and a decrease in pro-inflammatory cytokine levels compared to the disease group.
However, no statistically significant change within groups was observed in terms of serum insulin
and anti-inflammatory cytokine levels. The improvement in diabetic symptoms, such as polyphagia,
polydipsia, and weight loss, was observed in the treatment group, along with pancreatic regeneration,
which indicated improved insulin secretion.

Conclusion:

In the current investigation, we concluded that CM and CM+ Resveratrol, as natural
immunomodulators, have the capacity to regenerate injured pancreatic beta cells and have antidiabetic
action, together with immunomodulating impact. Nonetheless, future studies on this therapy
appear to be promising.
3-Phosphoinositide-Dependent Kinase 1 as a Therapeutic Target for Treating Diabetes
Authors: Xiang Xie , Shuya Pan , Jiamin Zhang , Zihan Zhang , Xumei Yang , Jingjin Liu
Published: March 2024

:

The role of 3-phosphoinositide-dependent kinase 1 (PDK1) has been welldocumented
in the development of diabetes. This review offers a thorough examination of its
composition and associated routes, specifically focusing on insulin signaling and glucose processing.
By examining the precise connection between PDK1 and diabetes, various strategies
specifically targeting PDK1 were also investigated. Additionally, recent discoveries from mouse
models were compiled where PDK1 was knocked out in certain tissues, which demonstrated encouraging
outcomes for focused treatments despite the absence of any currently approved clinical
PDK1 activators. Moreover, the dual nature of PDK1 activation was discussed, encompassing
both anti-diabetic and pro-oncogenic effects. Hence, the development of a PDK1 modifier is
of utmost importance, as it can activate anti-diabetic pathways while inhibiting pro-oncogenic
pathways, thus aiding in the treatment of diabetes. In general, PDK1 presents a noteworthy opportunity
for future therapeutic strategies in the treatment of diabetes.
Atrial Natriuretic Peptide as a Biomarker and Therapeutic Target in
Cancer: A Focus on Colorectal Cancer
Authors: Mehrabadi Shima , Velayati Mahla , epubi Nima , Mollazadeh Samaneh , Avan Amir
Published: March 2024

One of the most prevalent cancers throughout the world is colorectal cancer (CRC).
Natriuretic peptides are important hormones that have a crucial role in the physiology of humans
and other animals. There are a variety of treatments for colon cancer. However, conventional
therapies have many side effects and low efficacy in the treatment of this disease. Atrial Natriuretic
Peptide (ANP) is one of the most well-known natriuretic peptides involved in regulating
blood pressure and blood volume. Studies have demonstrated that ANP has a therapeutic effect
on different cancer types. The anti-tumor effect of ANP is exerted by inhibiting DNA synthesis
but not inducing apoptosis. The anti-proliferative role of ANP has been reported in human
breast, prostate, colon, pancreatic, lung, and ovarian cancer and in many other tumors. Therefore,
we review the recent papers on natriuretic peptides in CRC as a common malignancy in
adults to assess the pathways of ANP involved in the progression of CRC and its effects on the
prevention or treatment of CRC and other cancer types.
Phenylketonuria Incidence based on the Results of the Neonatal Screening Program and Evaluation of this Program-based Surveillance Data System in Sirjan City from 2012 to 2019
Authors: Rezabeigi-Davarani Fatemeh , Kermani Bahareh , Raesi Rasoul , Daneshi Salman
Published: March 2024

Background

PKU is the most common hereditary metabolic disease. Considering the severe complications caused by the lack of timely diagnosis of this disease, it is important to carry out the newborn screening process properly.

Aim

This study aims to determine the incidence of phenylketonuria (PKU) based on the results of the neonatal screening program and evaluate the indicators of this program in Sirjan City from 2012 to 2019.

Methods

The present study was across-section descriptive, and all screening babies were examined from 2012 to 2019. Screening information was obtained from data recorded in the neonatal screening program and patient information from the national form of epidemiological investigation of genetic diseases in the Kerman Health Department. Excel software was used to draw charts. Descriptive statistics were used to describe the variables. Information was provided as a frequency table and chart.

Results

The overall screening coverage was 95.3%. Among this, 93.2% of infants were screened during the 3 to 5 days of life. The incidence of PKU was found to be 1.33 in 10,000 live births. Around 0.44% of the samples were inappropriate, and the percentage of inappropriate samples was from the beginning of the program and monitored across each year. On the first visit to the PKU treatment center, 50% of infants were below 2 weeks. About 100% of patients identified in screening were the first child in the family, and around 83.3% of parents were consanguineous.

Conclusion

The incidence of PKU in Sirjan is in line with the national average. Implementation of the screening program showed a significant impact on the timely diagnosis and the onset of patients. It is necessary to increase household awareness about the consequences of consanguineous marriages, especially in areas with a high prevalence of PKU.
The Botany, Phytochemistry, Pharmacology, Toxicology, and Quality Control of Epimedium: A Review
Authors: Wang Tao , Kong Xiangfeng , Tang Xiaomeng , Xie Mingxia , Zhang Xia , Zhao Jianjun , Gao Xiaojuan , Wang Hanqing
Published: March 2024

:

Epimedium has long been used as an ethnic drug in Asia and Europe for its high medicinal
value and health benefits, which is often used for anti-tumor, anti-osteoporosis, sexual dysfunction,
and other related diseases. In this research, Epimedium isreviewed in the botany, phytochemistry,
pharmacology, toxicology, processing, and quality control to make it better for clinical services.
More than 106 compounds, including flavonoids, polysaccharides, alkaloids, lignans, and others,
were isolated from Epimedium. Based on multiple chemically active components, Epimedium has a
wide range of pharmacological action. Several studies have demonstrated Epimedium has multiple
biological activities, including neuroprotective effects, anti-inflammatory, anti-aging, and antioxidant
effects, anti-osteoporosis, anti-cancer, anti-tumor, anti-diabetes, anti-influenza, effects on sexual
dysfunction, etc. Recently, the toxicity of Epimedium has been brought into focus, and its hepatotoxicity
has been confirmed through animal experiments. Moreover, it is particularly important to control
its quality. To date, great progress has been made in the study of Epimedium. This study systematically
reviews the achievements of research on Epimedium. Moreover, the shortcomings of the
current research on Epimedium were pointed out, and some suggestions were given.
Energy Consumption Optimization for the Cold Source System of a
Hospital in Shanghai-Part I: Analysis of Operating Characteristics and the
Control Strategies of the Chillers
Authors: Qu Minglu , Luo Xiang , Zhang Xinlin , Yan Xufeng , Li Zhao , Wang Lihui
Published: March 2024

Background:

Hospitals account for the most proportion of energy consumption in the
public building sector. Chillers usually account for most of the overall energy consumption of the
cold source system.

Objective:

To solve the problem of chillers' large energy consumption problem, novel technologies
were developed, and achievements were patented.

Methods:

The operating characteristics influencing factors of the magnetic suspension centrifugal
chiller (MSCC) and variable frequency screw chiller (VFSC) of a hospital in Shanghai were analyzed
and discussed by actual measurements. Then, based on the operating characteristics of the
chiller obtained from the analysis of the measured data, the cooling capacity was classified by the
K-Means clustering method to obtain the startup strategy of the chillers.

Results:

The effects of the supply chilled water temperature, the supply cooling water temperature
and variable cooling water flow rate on the maximum cooling capacity and coefficient of performance
(COP) of both chillers were explored. The load distribution scheme was discussed based on
the chillers' startup strategy.

Conclusion:

The average part load ratio operation scheme was the preferred chiller distribution
scheme. A chiller's maximum allowable part load ratio should not exceed 80% during the low-load
operation period and should not be less than 60% during the conventional operation period. It provided
a reference for optimizing the chiller operation strategy to reduce system energy consumption.
Effectiveness of a Smartphone App–Based Intervention With Bluetooth-Connected Monitoring Devices and a Feedback System in Heart Failure (SMART-HF Trial): Randomized Controlled Trial
Authors: Yoon Minjae , Lee Seonhwa , Choi Jah Yeon , Jung Mi-Hyang , Youn Jong-Chan , Shim Chi Young , Choi Jin-Oh , Kim Eung Ju , Kim Hyungseop , Yoo Byung-Su , Son Yeon Joo , Choi Dong-Ju
Published: March 2024

Background

Current heart failure (HF) guidelines recommend a multidisciplinary approach, discharge education, and self-management for HF. However, the recommendations are challenging to implement in real-world clinical settings.

Objective

We developed a mobile health (mHealth) platform for HF self-care to evaluate whether a smartphone app–based intervention with Bluetooth-connected monitoring devices and a feedback system can help improve HF symptoms.

Methods

In this prospective, randomized, multicenter study, we enrolled patients 20 years of age and older, hospitalized for acute HF, and who could use a smartphone from 7 tertiary hospitals in South Korea. In the intervention group (n=39), the apps were automatically paired with Bluetooth-connected monitoring devices. The patients could enter information on vital signs, HF symptoms, diet, medications, and exercise regimen into the app daily and receive feedback or alerts on their input. In the control group (n=38), patients could only enter their blood pressure, heart rate, and weight using conventional, non-Bluetooth devices and could not receive any feedback or alerts from the app. The primary end point was the change in dyspnea symptom scores from baseline to 4 weeks, assessed using a questionnaire.

Results

At 4 weeks, the change in dyspnea symptom score from baseline was significantly greater in the intervention group than in the control group (mean –1.3, SD 2.1 vs mean –0.3, SD 2.3; P=.048). A significant reduction was found in body water composition from baseline to the final measurement in the intervention group (baseline level mean 7.4, SD 2.5 vs final level mean 6.6, SD 2.5; P=.003). App adherence, which was assessed based on log-in or the percentage of days when symptoms were first observed, was higher in the intervention group than in the control group. Composite end points, including death, rehospitalization, and urgent HF visits, were not significantly different between the 2 groups.

Conclusions

The mobile-based health platform with Bluetooth-connected monitoring devices and a feedback system demonstrated improvement in dyspnea symptoms in patients with HF. This study provides evidence and rationale for implementing mobile app–based self-care strategies and feedback for patients with HF.

Trial Registration

ClinicalTrials.gov NCT05668000; https://clinicaltrials.gov/study/NCT05668000
Research on the Advantages and Practice Paths of Cultivating and Practicing Values in Huangmei Opera Vocational Education
Authors: Dai Xianying
Published: March 2024

It has unique advantages to cultivate and practice justice values in Huangmei Opera vocational education, because Huangmei Opera not only contains traditional values, but also can express values as people’s values, moral norms and codes of conduct through intuitive and specific artistic images. Therefore, cultivating values in Huangmei Opera vocational education has unique advantages in yuan cultivation and communication. This also opens up a new path of vocational education.
Govorna (dis)fluentnost u kontekstu forenzičke fonetike
Authors: Žagmešter Ana , Bašić Iva ,   University of Zagreb, Faculty of Humanities and Social Sciences
Published: March 2024

Na snimljenome korpusu od sedam studentica i sedam studenata Filozofskoga fakulteta u Zagrebu ispitana je distribucija različitih kategorija disfluentnosti zapaženih u različitim govornim stilovima i zadatcima. Prema analiziranome korpusu načinjena je klasifikacija disfluentnosti podijeljenih u dvije veće skupine: oklijevanja i samoispravljene pogrješke. U radu su analizirani i vremenski parametri govora (tempo govora i tempo artikulacije), koji su dovedeni u odnos s učestalošću pojavljivanja disfluentnosti. Doneseni su zaključci o distribuciji disfluentnosti prema tipu govornoga stila i prema spolu, a uočene su i pojedinačne osobitosti koje upućuju na idiosinkratičnost u govoru. Govorne disfluentnosti istaknule su se kao snažan govorni marker pri prepoznavanju govornika u području forenzičke fonetike, čija se osobitost ogleda u tome da ih kao govornici teško kontroliramo (maskiramo), dosljedno ih koristimo te koristeći ih odražavamo način na koji jezično planiramo govor. Među disfluentnostima poseban značaj za prepoznavanje govornika imaju pune stanke koje pokazuju vrlo malu varijabilnost unutar istoga govornika, čime pridonose idiosinkratičnosti govornika u odnosu na druge govornike istoga jezika.
Analysis of Coercion-Resistant for E-Voting System based on Blockchain
Authors: Rao P. V. V. S. Eswar , Sheik Tanveer , Shaik Sabhiya , Kandula Dhanunjaya , Kodamanchili Navya Sri , SMIEEE P. Siva Kumar
Published: March 2024

Abstract: Election absenteeism rates are steadily rising, partly a result of the distance required to cast a vote. The use of electronic voting procedure would eliminate the need for travel and enhance voter turnout. In addition, compared to the conventional paper ballot voting technique, this reduces dangers like manipulations and produces results more quickly. A remotely electronic voting system should, nevertheless, adhere to the highest standards of security, dependability, and transparency given the significance of an election. Numerous remote e-voting systems, many of which are based on blockchain technology, were examined in this literature review. Blockchain technology provides for the removal of the Trusted Third Party (TTP) and the decentralization of transactions while also providing transparent and completely secure data storage, making it a new technical foundation for many different types of IT applications. The use of smart-contract technology, which automates and executes user agreements, is also permitted. The authors of this study examine the most insightful blockchain-based e-voting options. The lack of openness and auditability in conventional voting methods can be addressed by blockchain technology. A reliable computing platform is offered by running a self-enforcing e-voting system on a blockchain for real-time data verification
(MIMO Buck Converter) Multi-Input Multi-Output DC-DC Buck Converter
Authors: Verma Vipin , Patel Aruna
Published: March 2024

Abstract: Designs of the power electronics circuitry are nowadays reducing the size, space, and weight of converter and inverter circuits. This is possible because of the availability of new high-switching frequency devices. This paper presents a generalized model of buck converters that is multi-input multi-output(MIMO) fixed and variable. The converter used for stepping down the voltage is called a buck converter. The buck converter is designed, analyzed simulated & developed. The proposed model of this Buck converter consists of two parts: (a) Main converter circuits with the components like switch, inductor, diode, capacitor, and load, (b) A control circuit for controlling the operation of the switch using 10 10-turn potentiometer. This model can accurately give the power output voltage.
KOMITMEN DENGAN PEMAAFAN DALAM HUBUNGAN PERSAHABATAN
Authors: Arif Try Abriansyah
Published: March 2024

Pada masa remaja, individu membentuk kelompok teman sebaya (peer group) yang di dalamnya timbul persahabatan. Salah satu unsur dalam persahabatan adalah komitmen. Dalam hubungan persahabatan, kadang individu melakukan kesalahan yang menyakiti sahabatnya. Untuk mempertahankan hubungan persahabatan, dibutuhkan pemaafan kepada individu yang melakukan kesalahan dalam persahabatan tersebut. Tujuan dari penelitian ini adalah ingin mengetahui hubungan komitmen dengan pemaafan dalam hubungan persahabatan. Penelitian ini menggunakan metode non-tes yaitu skala pemaafan dan skala tingkat komitmen dengan model skala likert. Jumlah subyek sebanyak 296 orang dengan rentang usia 18 tahun - 22 tahun. Hasil penelitian menunjukkan bahwa ada hubungan antara tingkat komitmen dengan pemberian pemaafan dibuktikan dengan hasil perhitungan korelasi product moment. Semakin tinggi tingkat komitmen dalam sebuah hubungan persahabatan maka akan semakin tinggi pula pemaafan yang diberikan kepada sahabat yang melakukan kesalahan (r = 0,355; p = 0,000; p < 0,01).Kata kunci: Komitmen, pemaafan, persahabatan
INTERNETPROJECTING IN THE ACTIVITY OF SOCIALLY ORIENTED NON-PROFIT ORGANIZATIONS OF THE SARATOV REGION
Authors:   Russian Presidential Academy of National Economy and Public Administration, Akaev D.V.
Published: March 2024

The experience of social project grant competition in the territory of Saratov region is analyzed. Both internal Internet communications of non-profit organizations and external ones with authorities and population are considered. Strengths and weaknesses of the project activity of non-profit organizations are studied, as well as the influence of Internet communications on them.
EFFECTIVE SOCIAL CAPITAL MANAGEMENT PRACTICES IN CONDITIONS OF HIGH UNCERTAINTY AND RISKS
Authors:   Russian Presidential Academy of National Economy and Public Administration, Khoroltseva E.B. , Fedorova A.V. ,   St. Petersburg Institute of Technology
Published: March 2024

Effective practices of social capital management in modern organizations are considered. Political, socio-economic and technological conditions of uncertainty and risks are analyzed. Effective models of modern organizations are investigated, comparative analysis of the models is carried out, strengths and weaknesses of social capital management at the organizational level are revealed. The results of conceptual studies are presented, the process of social capital management is evaluated.
“HATE SPEECH” AS A FACTOR OF SOCIAL CONFLICT
Authors:   Yuri Gagarin State Technical University of Saratov, Feklina E.M. , Shelyakhina N.V. ,   Yuri Gagarin State Technical University of Saratov
Published: March 2024

The article highlights the problem of the emergence of “hate speech” based on interethnic and interstate conflicts. The factors influencing the emergence of extremism and hate crimes are identified. The measures taken to resolve interethnic conflicts and curb their escalation at the state level, as well as models of social cohesion as a mechanism for regulating social conflicts are analyzed.
SPECIFICS OF THE RUSSIAN FEDERATION MILITARY-TECHNICAL POLICY FORMATION AND IMPLEMENTATION MECHANISM
Authors:   Chelyabinsk State University, Stezhko V.V.
Published: March 2024

Issues of the organizational essence, management structure, technology of functional development and methodology of program-target planning of the mechanism of formation and implementation of the Russian Federation military-technical policy are studied. Its content in context of practical purposes, the creation of combat and shock systems is analyzed.
A review of Artificial Intelligence Algorithms (Machine Learning Algorithm) for Intrusion Detection in Software-Defined Networking
Authors: Heymann Reolyn , Ahirhima Victor
Published: March 2024

Demands for flexible and seamless system management necessitated the
growth of software-defined networks (SDN). Yet, securing these
environments with effective measures is critical as SDN continues to
evolve into more intricate architectures. Intrusion detection is
paramount among these measures; thus far, studies suggest that
artificial intelligence (AI) approaches may be helpful in this domain.
By systematically examining relevant works addressing AI-based intrusion
prevention strategies within hyper-evolved SDN settings, our review aims
to present an inclusive evaluation alongside suggesting areas requiring
additional scrutiny. This research introduces readers to key concepts
related to SDN and how deep learning algorithms, machine learning
algorithms, and neural networks can be applied for effective intrusion
detection within an SDN environment. Drawing from existing literature on
this subject matter, our analysis critically examines the benefits and
drawbacks of these AI-based techniques while highlighting gaps in
knowledge requiring further research attention. Some areas include
real-time protection capabilities, scalability concerns, and seamless
integration with different security mechanisms. We then present future
research directions in this area. This literature review employs a
systematic approach to elucidate the current research on using AI
methods to detect intrusions in SDN.
Struktura majątkowa a rentowność gospodarstw rolniczych o różnych kierunkach produkcji
Authors: Felczak Tomasz , Domańska Teresa
Published: March 2024

Celem opracowania jest identyfikacja i określenie zróżnicowania struktury majątku i rentowności działalności gospodarstw rolniczych z regionu Mazowsze i Podlasie w zależności od kierunku produkcji. (fragment tekstu)
Strategic Bias in Team Members’ Communication about Relative Contributions: The Effects of Voluntary Communication and Explanation
Authors: Berger Leslie , Guo Lan , Matthews Kelsey , Wong Christopher
Published: March 2024

One significant challenge of motivating team performance is that the contribution of individual team members is difficult to observe. In this setting, managers often seek private information about team members’ relative contributions to help allocate team bonuses. However, the presence of self-interested biases in such communication, especially strategic bias, could reduce its informational value. We study the effects of two features of team members’ communication about their relative contributions—whether it is mandatory or voluntary and whether an explanation is required—on the severity of employees’ self-interested biases in their communication. As predicted, experimental results show that when explanations are not required, low-ability team members incorporate more strategic bias into their relative contribution communication when it is voluntary, compared to mandatory. We also observe that among low-ability team members, the greater strategic bias observed when the relative contribution communication is voluntary, compared to mandatory, diminishes when an explanation is required.

Data Availability: Data are available from the authors upon request.
Analyst/Investor Days and Firms’ Information Environments
Authors: Park Min
Published: March 2024

SYNOPSIS

This paper investigates the impact of analyst/investor days on hosting firms’ information environments. The event allows for human interaction and information exchange among participants. Using hand-collected data, I document the impact of analyst/investor days on the hosting firms’ information environments in two different periods: an immediate effect around the time of the event and a persisting effect around future earnings announcements. First, I show that the inaccuracy of analysts’ forecasts for various forecast horizons significantly decreases around the event. Second, I find evidence that analyst/investor days decrease information asymmetry and improve analyst forecast quality around future earnings announcements. This result suggests that the information effects persist into the future and help investors and analysts better interpret future earnings releases. Overall, this study documents the forward-looking and multidimensional nature of information disclosed at analyst/investor days in the context of sequential disclosures.

JEL Classifications: M41; G14; G24; G32.
Implementing ERP with Maintenance and Support in Mind: Exploring the Efficacy of Application Management Services for the Post-Implementation Phase
Authors: Bradford Marianne , Bucy Robert A. , Adivar Murat
Published: March 2024

Prior ERP research has focused primarily on adoption and implementation; however, in an ERP implementation, maintenance and support (M&S) also has a significant impact on the long-term viability and financial expenditures of organizations. Many organizations turn to application management service (AMS) providers to manage ERP M&S. We surveyed professionals knowledgeable in their companies’ use of AMS for ERP. We find associations between variables consistent with a business case of “keep the lights on” versus “value-driven” partnership and benefits achieved from the arrangement. We also examine activities that should lead to more M&S success: customization, quality documentation, and process standardization. We find associations between some of these variables and (1) more focus on M&S during implementation, (2) challenges transitioning to AMS, and (3) quality of AMS support. Our results are a first step toward research in AMS for ERP M&S and add to the AIS literature on the ERP post-implementation stage.

Data Availability: Data available upon request.
Comparison of alveolar bone morphology after expansion with hybrid and conventional Hyrax expanders
Authors: Silva Ivan , Miranda Felicia , Bastos José Carlos da Cunha , Garib Daniela
Published: March 2024

Objectives

To compare the buccal and palatal bone changes of maxillary posterior teeth produced by hybrid hyrax (HH) and conventional hyrax (CH) expanders in growing patients.

Material and Methods

A sample of 32 patients with posterior crossbites in the late mixed dentition was recruited and randomly allocated into two groups. Group HH was composed of 18 individuals with a mean age of 10.7 years (six female, 12 male) treated with a hybrid expander with two anterior parasagittal miniscrews. Group CH was composed of 14 individuals with a mean age of 11.4 years (six female, eight male) treated with a conventional Hyrax expander. Cone-beam computed tomography (CBCT) exams were obtained before expansion (T1) and after 11 months when the expander was removed (T2). Buccal and palatal bone plate thickness and height of maxillary posterior teeth were measured. Intergroup comparisons were performed using t or Mann-Whitney tests (P < .05).

Results

The CH group showed greater decreases of the buccal bone plate height (mean change: 1.27 mm) at the maxillary first premolars compared to the HH group (mean change: 0.11 mm, P = .001). No intergroup difference was found for changes in the buccal and palatal bone thickness.

Conclusions

Hybrid expanders showed a tendency to cause less negative impact on the buccal bone plate height of first premolars compared to conventional Hyrax expanders. However, the difference was not clinically significant. Both hybrid and conventional Hyrax expanders are safe for the alveolar bone morphology in the late mixed dentition.
Polygenic Risk for Type 2 Diabetes in African Americans
Authors: Irvin Marguerite R. , Ge Tian , Patki Amit , Srinivasasainagendra Vinodh , Armstrong Nicole D. , Davis Brittney , Jones Alana C. , Perez Emma , Stalbow Lauren , Lebo Matthew , Kenny Eimear , Loos Ruth J.F. , Ng Maggie C.Y. , Smoller Jordan W. , Meigs James B. , Lange Leslie A. , Karlson Elizabeth W. , Limdi Nita A. , Tiwari Hemant K.
Published: March 2024

African Americans (AAs) have been underrepresented in polygenic risk score (PRS) studies. Here, we integrated genome-wide data from multiple observational studies on type 2 diabetes (T2D), encompassing a total of 101,987 AAs, to train and optimize an AA-focused T2D PRS (PRSAA), using a Bayesian polygenic modeling method. We further tested the score in three independent studies with a total of 7,275 AAs and compared the PRSAA with other published scores. Results show that a 1-SD increase in the PRSAA was associated with 40–60% increase in the odds of T2D (odds ratio [OR] 1.60, 95% CI 1.37–1.88; OR 1.40, 95% CI 1.16–1.70; and OR 1.45, 95% CI 1.30–1.62) across three testing cohorts. These models captured 1.0–2.6% of the variance (R2) in T2D on the liability scale. The positive predictive values for three calculated score thresholds (the top 2%, 5%, and 10%) ranged from 14 to 35%. The PRSAA, in general, performed similarly to existing T2D PRS. The need remains for larger data sets to continue to evaluate the utility of within-ancestry scores in the AA population.

Article Highlights
EMACrawler: Web Arama Motoru Veritabanı Tazeliği Optimizasyonu
Authors: Alanoğlu Zülfü , Akcayol M. Ali
Published: March 2024

Günümüz bilgi ve teknoloji çağında arama motorları hayatımızın önemli bir parçası haline gelmiştir. Her ne kadar bilgiye erişimde ilk başvurulan arama motorları olsa da kullanıcılara sunulan içerikte eski ve gereksiz bilgiler yer almaktadır. Güncel verileri sağlamak açısından günümüzdeki arama motorları çoğunlukla istenen başarıyı sunamamaktadır. Web tarayıcılarının sunduğu verilerin güncelliğini sağlamak için tekrar ziyaret zamanının doğru tahmin edilmesi gerekmektedir. Bu çalışmada arama motorlarının performanslarını etkileyen en önemli özellik olan tekrar ziyaret zamanlarının belirlenmesi için üstel hareketli ortalamaya dayanan EMACrawler önerilmiştir. Önerilen yöntem kesinlik, toplam kapsama alanı ve verimlilik metrikleri kullanılarak test edilmiştir. EMACrawler’ın web sayfalarındaki güncel veriyi doğru tahmin zamanında ve hızlı bir şekilde elde ettiği görülmüştür. Yapılan deneysel çalışmaların sonucunda EMACrawler’ın güncel verilerin elde edilmesi ve tarayıcı veri tabanının tazeliğinin korunmasında diğer yöntemlerden daha başarılı olduğu görülmüştür.
Correlation between Dermatology Life Quality Index and Psoriasis Area and Severity Index in Patients with Psoriasis: A Cross-sectional Global Healthcare Study on Psoriasis
Authors: Maul Julia-Tatjana , Maul Lara W. , Didaskalu Johannes A. , Valenzuela Fernando , Romiti Ricardo , Peterson Hannah , Korouri Edwin , Novoa Farah , Oon Hazel H. , Zheng Min , Wu Jashin J. , Thyssen Jacob P. , Egeberg Alexander , Armstrong April W. , Nielsen Mia-Louise
Published: March 2024

Quality of life impairment in dermatology patients and severity of psoriasis are quantified by the Dermatology Life Quality Index (DLQI) and the Psoriasis Area and Severity Index (PASI), respectively. The aim of this study is to compare the correlation between PASI and DLQI in patients from different geographical areas and to identify predictors of high DLQI across geographical regions. Correlations between PASI and DLQI were evaluated using Spearman’s rank correlation tests and quantile regression. The study included 1,158 patients with psoriasis, with a median (interquartile range) PASI and DLQI of 6.0 (3.0–12.0) and 8.0 (4.0–15.0), respectively. Correlations were demonstrated between PASI and DLQI, both overall and stratified by geographical region. Quantile (median) regression yielded coefficients of 0.75 (95% confidence interval (95% CI) 0.62, 0.88) for Switzerland, 0.50 (95% CI 0.42, 0.58) for Latin America, 0.34 (95% CI 0.16, 0.51) for Asia, and 0.31 (95% CI 0.08, 0.53) for the USA. Current age, age at diagnosis, sex, body mass index, and psoriasis arthritis affected DLQI in Latin America, while education had an impact among patients treated in Switzerland. Few countries were included within each continent; hence, more data from different countries are necessary for generalizability. The study showed correlations between PASI and DLQI among patients in all included geographical regions. The patients’ characteristics affecting DLQI vary worldwide.
Modeling banking efficiency in the MENA region between 2017 and 2021: Data Envelopment Analysis approach
Authors:   Université Mohammed V, Rabat, Maroc, Benbachir Soufiane
Published: March 2024

In this paper, we applied the Data Envelopment Analysis model under the assumption of variable returns to scale and output orientation to measure the efficiency of banks belonging to 12 MENA countries during the period 2017-2021. We divided the banks into two classes, conventional banks comprising 59 banks belonging to 11 countries and Islamic banks comprising 22 banks belonging to 7 countries. Concerning the 59 conventional banks, the results showed that the percentage of CCR-efficient conventional banks is low and does not exceed 16% and the average CCR-efficiency score reached 90% during the study period. We also found that Qatar is the only country whose conventional banks are BCC-efficient for all 5 years in a row, and that their CCR-efficiency scores are the highest, whereas conventional banks in Morocco and Jordan have the lowest average CCR-efficiency scores. For the 22 Islamic banks, the results showed that the percentage of CCR-efficient Islamic banks was low, at just 14%, and that their average CCR-efficiency score was 64%. We also found that Qatar is the only country whose Islamic banks are on average CCR-efficient over the 5 years, and that Moroccan Islamic banks have the lowest average CCR-efficiency score, reaching 36%.
Python for financial engineers: Mastering four moments in portfolio management
Authors:   Université Chouaib Doukkali, El Jadida, Maroc, Chafik Mohamed Amine , Benslimane Adda ,   Université Chouaib Doukkali, El Jadida, Maroc, Boussedra Faouzi ,   Université Chouaib Doukkali, El Jadida, Maroc
Published: March 2024

This research conducts a comprehensive analysis aimed at optimizing portfolios comprising 14 stocks listed on the Moroccan stock exchange. Our journey culminates in the construction of portfolios that are meticulously designed to maximize returns while prudently managing risk. These portfolios are the result of an exhaustive Monte Carlo simulation that explored over three million unique portfolio combinations. The simulations take into account the skewness and kurtosis of the return distributions, offering investors a robust framework for decision-making. We collected historical data for theses 14 stocks on the Moroccan market exchange by accessing 5 years' worth of historical data from investing.com.We explore the concepts of Modern Portfolio Theory (MPT), which forms the backbone of our approach, and we employ the power of mathematics and Python programming to bring forth insights that can inform sound investment decisions. The primary focus of this study centers on the incorporation of higher statistical moments from the returns of key financial indices, with a particular emphasis on their skewness and kurtosis characteristics. To achieve this goal, various evaluative criteria derived from these statistical parameters are introduced and thoroughly investigated. Within this research framework, we confront a spectrum of optimization challenges, including the maximization of skewness, and minimization of kurtosis.
Akuaponik dan Hidroponik Sederhana: Strategi Mencapai Ketahanan Pangan untuk Pencegahan Stunting
Authors: Novita Ratnasari  , Gilang Ramadhani  , Agustin Eka Putri  , Nadiya Maulida  , Mustika Nurul Indah Safitri  , Muflihatun  , Tri Wulandari  , Sharikha Ruwaida Zukhrufa  , Ulil Wafa Khorul Muna  , Az-Zatun Nabila  , Asri Dwi Ariyani
Published: March 2024

Prevalensi stunting di Kabupaten Pemalang masih tinggi yaitu 6.426 kasus stunting yang masih belum tertangani. Oleh karena itu, tujuan dari pengabdian ini adalah sosialisasi untuk menerapkan sistem akuaponik dan hidroponik di Desa Jebed Utara Kecamatan Taman Kabupaten Pemalang. Kegiatan pada saat sosialisasi berisi demonstrasi mengenai penerapan akuaponik dan hidroponik serta mempraktikkan bersama para peserta. Metode pelaksanaan pengabdian masyarakat ini terdiri dari tiga kegiatan, dimulai dari tahap observasi, tahap persiapan, dan tahap pelaksanaan. Kegiatan sosialisasi ini dihadiri oleh 27 orang yang berasal dari perwakilan masing-masing organisasi desa. Penerapan akuaponik dan hidroponik disarankan karena dapat diterapkan pada lahan yang terbatas, hemat penggunaan air, dan tidak membutuhkan pupuk. Adapun hasil dari pengabdian ini adalah memberikan pengetahuan bagi masyarakat khususnya di Desa Jebed Utara terkait penerapan sistem akuaponik dan hidroponik pada lahan sempit dalam upaya peningkatan pangan untuk pencegahan stunting di Desa Jebed Utara. Penerapan akuaponik dan hidroponik diharapkan mampu menjadi salah satu upaya meningkatkan ketahanan pangan bagi masyarakat setempat dalam upaya pencegahan stunting.
Audio Visual Media Based on Problem Based Learning Water Cycle Topics for Class V Elementary School
Authors: I Komang Adi Prayoga  , I Gusti Ayu Tri Agustiana
Published: March 2024

Learning media is used to convey messages to educators and students. The lack of use of technology-based media causes students to experience difficulties in understanding complex science material. This research aims to create audio-visual learning media with a PowerPoint application based on problem-based problem-based learning on the water cycle topic for fifth-grade elementary school students. This research uses the ADDIE model. The data collection methods and instruments used in this research are questionnaires, rating scales, and tests. The subject of this research is a product in the form of audio-visual learning media with a Powtoon application based on problem-based learning on the water cycle. At the same time, the object of development is content validity, practicality, and product effectiveness. The data analysis technique uses qualitative and quantitative descriptive analysis. The research results showed that the level of media validity was in the very good category. The results of the effectiveness test of audio-visual media with the Powtoon application based on Problem-Based Learning show that there is a significant difference between audio-visual learning media and the Powtoon application based on problem-based learning on the topic of the water cycle for the fifth-grade elementary school students on learning outcomes. So, the learning media developed is feasible and effective to improve student learning outcomes. This research implies that teachers can use video media in learning.