bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-Acting Reversible Contraception (LARC) and Early Childbearing Revisited: Births and Birth Intendedness After LARC Removal in a State Medicaid Population (2012–2020)
Authors: Rendall Michael S. , Eeckhaut Mieke C. W. , Gifford Katie , Hurtado-Acuna Constanza
Published: October 2024

Objectives. To analyze births and birth intendedness after long-acting reversible contraception (LARC) removal among Medicaid-insured women.

Methods. We linked all Delaware women with a Medicaid-covered LARC removal in 2012 to 2020 (n = 8047) to birth records and to Pregnancy Risk Assessment Monitoring System (PRAMS) pregnancy intendedness survey responses (n = 241).

Results. Births within 3 years of a Medicaid-covered LARC removal were much more likely to be to women in their 20s compared with all Medicaid births (63.5% vs 53.4%; P < .001). The intended proportion for births within 3 years of Medicaid-covered LARC removal (65.2%) was higher than for all Medicaid-covered births (58.8%; P = .08) and was consistently above 60% across all age groups younger than 30 years.

Conclusions. A state Medicaid-insured population’s use of highly effective reversible contraception was associated with births being concentrated among women in their 20s and with consistently high fractions of intended births across younger ages at birth.

Public Health Implications. Programs and policies may consider LARC access for its potential to increase low-income women’s reproductive autonomy by enhancing their ability to achieve births at the age of their choosing. ( Am J Public Health. 2025;115(1):95–102. https://doi.org/10.2105/AJPH.2024.307844 )
Acercando el zoom. La fotografía como relato pedagógico con mirada feminista en los Grados de Educación
Authors: Jiménez-Millán Azahara , Pérez Gracia Elisa , García-Cano Torrico María , Hinojosa Pareja Eva F.
Published: October 2024

El artículo se enmarca en un proyecto de innovación docente (2022-4-4001) desarrollado en el curso académico 2022/2023 en 2º curso en los Grados de Educación Infantil y Educación Primaria en la asignatura Diversidad, Convivencia y Educación Inclusiva. Se utilizó la fotografía para narrar, reflexionar y mejorar el proceso de enseñanza-aprendizaje individual y colectivo. Desde los paradigmas feministas con los aportes de la pedagogía crítica, se han propuesto como objetivos (1) comprender un conjunto de conceptos vinculados a la igualdad de género de manera transversal en la asignatura y (2) establecer vínculos entre este aprendizaje con las vivencias y experiencias durante el proceso de realización de un proyecto que aúna la metodología Aprendizaje-Servicio (ApS) y narración fotográfica (fotolibros). Las actividades realizadas se organizan en dos fases. La primera con talleres formativos sobre el uso de la fotografía como herramienta pedagógica; y la segunda con el desarrollo del proyecto ApS que incluye la narración fotográfica en fotolibros. Los resultados confirman los beneficios de situar al estudiantado como protagonista de su proceso de aprendizaje e interrogar las representaciones dominantes. Para concluir, la oportunidad de aunar ApS y narración fotográfica como herramienta para la transformación social desde la participación y la reflexión feminista.
Flexibilidad y asincronía para favorecer la conciliación de los estudios superiores con el trabajo.
Authors: Ros Turégano Salvador Javier
Published: October 2024

El objetivo del trabajo es presentar un modelo de educación superior inclusivo que permita la conciliación de la vida académica con la vida laboral y familiar del alumnado más vulnerable desde el punto de vista socioeconómico. Para ello se ha hecho un estudio de antecedentes de los modelos más flexibles y se han extraído cinco acciones para aplicar a todas las asignaturas: rediseñar toda la programación, usar de un sistema de gestión online, programar sobre la marcha, optimizar el aprendizaje mediante el uso de la tecnología y diseñar las actividades para ejecutarlas indistintamente de manera síncrona o asíncrona. Se ha definido el modelo Aula Universal como aquél que incorpora todas esas características. A continuación se ha implementado el modelo en asignaturas de los títulos superiores de diseño y se han evaluado los resultados de un grupo clase. Se concluye que esta aplicación del sistema ayuda a conciliar el trabajo con los estudios, hace que participe más alumnado y mejora los resultados de aprendizaje de todo el grupo clase.
Elaboración y uso estratégico de los recursos didácticos tecnológicos y su impacto en el aprendizaje de la asignatura tecnologías de la información y las comunicaciones aplicadas a la enseñanza de la Historia.
Authors: Sánchez González Jhonatan José
Published: October 2024

Los recursos didácticos tecnológicos juegan en la actualidad un papel relevante en el proceso de enseñanza y aprendizaje; la elaboración y el uso estratégico en los cursos virtuales impactan de manera significativa el aprendizaje de los participantes involucrados. La presente buenas prácticas se desarrolló en los meses de noviembre y diciembre 2023 en la asignatura "Tecnologías de la Información y las Comunicaciones Aplicadas a la Enseñanza de la Historia," del programa de la Maestría en Historia con orientación a la Enseñanza. Se empleó una metodología mixta de alcance descriptivo para evaluar la percepción de los participantes respecto al uso e impacto de los Recursos Didácticos Tecnológicos en el proceso de aprendizaje. Se desarrollaron dos fases: la primera consistió en elaboración de los recursos didácticos tecnológicos y la segunda el uso de los recursos didácticos tecnológicos. Los resultados obtenidos revelan una valiosa evaluación de la percepción de los participantes con respecto al uso y al impacto de los recursos como herramienta de apoyo en su proceso de aprendizaje.
Innovations of cellular automata
Authors: Srinivasan Krishna Kannan , Donovan Jordan , Harrigan Connor
Published: October 2024

In the past several years, there has been a rather substantial uptick in the amount of research within the realm of cellular automata due to its ability to produce complex, self-organizing behavior from simplistic rulesets. The capability to produce this behavior is essential to understanding artificial life and intelligence. This uptick has resulted in numerous novel directions for experimentation within this computational playground. This work summarizes a few of the most impactful directions that have resulted from this research.
SIENNA: A Generalizable Parameter-Efficient Machine Learning Diagnostic for Clinical Magnetic Resonance Imaging
Authors: Paluh Janet , Sunil Sreya , Rajeev Rahul , Chatterjee Ayan , Pilitsis Julie , Mukherjee Amitava
Published: October 2024

Contemporary machine learning models for computer vision, although abundant, are largely inappropriate for clinical diagnostics. Clinical sophistication must address data consistency, avoid large parametric needs to reduce model complexity, and achieve stable generalizability across new patient data. Here, we achieve these goals in SIENNA a “Lightweight Energy-efficient Adaptive Next generation” artificial intelligence (LEAN AI) platform along with development of new algorithms for DICOM data consistency and approaches for improved integration of clinical data with deep learning architectures. Applied in the context of brain tumor diagnostics, SIENNA is a nimble AI that requires 175K-285K trainable parameters, 122X less in comparison to other state-of-the-art AI ML tumor models, while outperforming these models. SIENNA is generalizable across diverse patient datasets in inductive tests on benchmark and clinical datasets, achieving high average accuracies of 93–96% in three-way multiclass classification of MRI tumor data, across mixed 1.5 and 3.0 Tesla data and machines. We apply no DICOM MRI data preprocessing beyond data consistency while achieving a parameter-efficient generalizable ML pipeline. SIENNA demonstrates that small clinical datasets can be sufficient to design robust clinical ready architectures to facilitate expanded ML applications in multimodal data integration in a wider range of clinical diagnostic tasks.
Circular RNA circDDX17 suppression to gastric cancer progression via the sponging miR-1208/miR-1279/FKBP5 axis encodes a novel circDDX17-63aa protein
Authors: Shao Shihe , Liu Tingjun , Ma Tieliang , Xue Jiaxin , Zhu Linqi , Cui Feilun , Zhang Haoliang
Published: October 2024

Mounting evidence indicates that circular RNAs (circRNAs) are dysregulated in human gastric cancer (GC). The downregulation of circDDX17 is linked to GC progression. However, the role and specific mechanism of circDDX17-mediated GC progression remains elusive. Herein, we report that the downregulation of circDDX17 was correlating with tumor growth and lymph node metastasis in patients with GC. CircDDX17 inhibited GC cell proliferation, migration, and epithelial-mesenchymal transition (EMT) while promoting apoptosis both in vitro and in vivo. Acting as a sponge for miR-1208 and miR-1279, circDDX17 regulated FKBP5 expression in GC cells. FKBP5, in turn, interacted with ERK1/2, influencing GC development through the ERK1/2 pathway. What is more, circDDX17 encoded circDDX17-63aa, which inhibited GC cell proliferation, migration, and EMT. In sum, CircDDX17 exhibits low-expressed in GC via the miR-1208/miR-1279/FKBP5 axis and circDDX17-63aa.
The Temporal Dynamics of Pathological Profile and Functional Impairment in Neuromyelitis Optica Spectrum Disorders associated Optic Neuritis
Authors: Yang Xiayin , Yao Shi-Qi , Chan Henry Ho-lung , Tan Shaoying
Published: October 2024

Background Optic neuritis (ON) linked to Neuromyelitis Optica Spectrum Disorders (NMOSD), particularly in Asians, causes irreversible vision loss. The lack of comprehensive analysis that tracks the progression of changes over time hinders the identification of optimal timeframes for observation and intervention of the disease. Our aim is to map disease progression histologically and functionally in an optimized Neuromyelitis Optica Spectrum Disorders associated Optic Neuritis (NMOSD-ON) animal model.Materials and Methods The animals in the NMOSD-ON group involved the injections of aquaporin-4-immunoglobulin G (AQP4-IgG) and human complement into the posterior optic nerve, separated by 24 hours, repeated twice. The control group received injections of normal immunoglobulin G (normal IgG) and human complement. Histological analyses examined the immunoreactivity of aquaporin-4 (AQP4) protein, glial fibrillary acidic protein (GFAP) protein (maker of astrocytes), microglial activation, myelin oligodendrocyte glycoprotein (MOG) (maker of myelin sheath), and degeneration of retinal ganglion cells (RGCs), along with gene expression profiling of inflammatory cytokines at various time points (Baseline, Day 2, Week 1, Week 2, Week 4). In-vivo visual functional and retinal structural assessments were performed weekly up to Week 4 to track disease progression.Results Administration of AQP4-IgG and human complement triggered a series of events in mice with NMOSD-ON, leading to early changes in astrocyte pathology (loss of AQP4 and GFAP staining), upregulation of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-1β (IL-1β), CXCL10, brain-derived neurotrophic factor (BDNF) and microglia activation in Week 1. This was followed by demyelination, culminating in damage to RGCs and nerve fibers in Week 2. Functionally, the delays of visual evoked potential N1 latency were detectable from Week 2, with reduced N1P1 amplitudes by Week 2. For the electroretinogram, the postive scotopic threshold response (pSTR) amplitude decreased at Week 2, while scotopic a- and b-wave amplitudes remained unchange, which corresponded to the retinal nerve fibre layer thinning in the in-vivo retinal structural scan commencing at Week 2.Conclusion This study outlines the progression timeline of NMOSD-ON disease and connects histological and molecular findings to retinal structural changes, in-vivo functional impariment following NMOSD-ON onset in an optimized animal model.
Onion membrane based composite scaffolds incorporated with N-Boc L-cysteine methyl ester enhances mineralization for bone tissue engineering applications
Authors: MV Sivasankar , Parcha Sreenivasa Rao
Published: October 2024

Composite scaffolds S1(C-MFC-PCL), S2 (C-MFC-PCL-H), and S3 (C-MFC-PCL-Zr) containing micro-fibrillated cellulose (MFC), chitosan (C), polycaprolactone (PCL), zirconium oxide (Zr), and hydroxyapatite (H) were synthesized by freeze-drying process. N-Boc-L-cysteine methyl ester (NBLCME) was synthesized and incorporated into the composite scaffolds S1, S2, and S3 at different concentrations (20–100µg/ml). FTIR analysis confirmed the interactions between S1, S2, S3, and NBLCME. SEM analysis showed that the S1, S2, and S3 had 70–85% porosity with a pore diameter range of 100–450µm. The scaffolds S1, S2, and S3 scaffolds achieved sustained drug delivery following Fickian diffusion behavior (n ≤ 0.45). The cytotoxic effects of NBLCME treated scaffolds (S1, S2, and S3) on MG63 cell line were studied by examining cell viability, alkaline phosphatase activity (ALP), Alizarin red S activity (ARS), and cell adhesion. The cytotoxicity of the treated scaffolds on MG63 cell line was dose-dependent, with no cytotoxic effects at concentrations below 60µg/ml. However, higher concentrations of NBLCME (> 60µg/ml) significantly reduced ALP and ARS activity of MG63 cells due to lactate dehydrogenase leakage. Composite scaffolds S1, S2, and S3 showed significant results in mechanical properties, swelling behavior, sustainable drug release, slow degradation rate, cell adhesion, growth, and proliferation. S3 composite scaffold exhibit excellent properties than other composite scaffolds S2 and S3. Therefore, S3 can be used as promising biomaterial for bone tissue engineering.
Semiautomatic 3D Ultrasound Kidney Volume Segmentation in Pediatric Hydronephrosis: Interrater Agreement and Correlation to Conventional Hydronephrosis Grading
Authors: Esser Michael , Tsiflikas Ilias , Jago James R. , Rouet Laurence , Stebner Alexander , Schäfer Jürgen F.
Published: October 2024

Background: Two-dimensional assessment of the kidney volume underestimates real kidney volume with a high interobserver variability. Limited data exist on innovative 3D ultrasound (3DUS) technique for the evaluation of pediatric hydronephrosis.
Objective: To evaluate the interrater agreement of kidney volume segmentation by 3DUS with a matrix array transducer in children with hydronephrosis and comparison of 3D metrics to conventional hydronephrosis grading.
Materials and methods: 48 kidney volumes were prospectively acquired in 45 patients with hydronephrosis by freehand 3DUS (6-1MHz volumetric sector array, electronic rotation; median age, 4years; 1month to 16years). Semi-automated kidney segmentation was performed by two independent readers providing volumes for total kidney (renal capsule), dilated collective system, renal parenchyma (renal capsule - collective system) and hydronephrosis index (renal parenchyma / renal capsule). Interrater agreement was evaluated with Bland–Altman plots, intraclass correlation coefficient (ICC) and Dice similarity coefficients. The maximum 2D diameter of renal pelvis was measured and hydronephroses were morphologically classified grade 1-4.
Results: Interrater agreement for renal capsule, collective system, hydronephrosis index and renal parenchyma was good to excellent with ICC of 0.94, 0.87, 0.83 and 0.92 respectively (p<0.001 each). Median Dice was 0.90 (capsule), 0.77 (collective system) and 0.88 (parenchyma). There was a positive correlation between hydronephrosis grading and ultrasonic hydronephrosis index and between renal pelvis diameter and collective system volume (p<0.001 both).
Conclusion: Semiautomatic 3DUS volumetric analysis has a high degree of interrater agreement providing parenchyma volume in hydronephrotic kidneys. Volumes of the collective system and hydronephrosis index correlate with the extent of hydronephrosis.
Trial registry: trial registration number, DRKS00022772; date of registration, 07/31/2020
Construction of a risk prediction model for sepsis-associated delirium in the intensive unit patients: A retrospective cohort study
Authors: Jiang Zeping , Wang Yusheng , Xie Tian , Liu Furong , Wan Rui , Xu Jiansui , Zhou Zaotian , Zhou Lan , Liu Yang
Published: October 2024

Background: To identify the risk factors associated with sepsis-associated delirium and to develop a nomogram for predicting the risk of delirium in patients with sepsis on the basis of the Medical Information Mart for Intensive Care IV database.
Methods: A total of 12029 patients from the Medical Information Mart for Intensive Care-IV database (MIMIC-IV 2.0) were divided into a training set and a testing set at a ratio of 7:3. The primary outcome was the occurrence of sepsis-associated delirium (SAD) in ICU patients with sepsis. Hierarchical logistic regression analyses were conducted in the training set, sequentially analyzing basic information and clinical features (Model 1) followed by additional nursing management factors (Model 2), to identify factors associated with the risk of SAD. These identified factors were utilized to construct a nomogram for predicting the risk of SAD. The predictive performance of the nomogram was evaluated via receiver operating characteristic curves and calibration curves.
Results: A total of 12,029 patients were enrolled, of whom 1,666 patients (13.3%) died in the hospital and 4,807 patients (39.96%) had SAD. In-hospital mortality in the SAD group was greater than that in the non-SAD group (23.4% vs. 7.5%, p < 0.001). By hierarchical logistic regression, two models were compared, and a nomogram integrating basic information, clinical features and easily overlooked nursing management factors was constructed. The risk factors for sepsis-associated delirium include age ≥ 65 years, tobacco use, SOFA score, intensive care unit (ICU) type at admission, hypernatremia, hypocalcemia and diet type on the first day. CRRT during sepsis and receiving skin care decrease the risk of sepsis-associated delirium. The AUCs of the developed model were 0.832 (95% CI 0.823–0.841) in the training set and 0.832 (95% CI 0.818–0.846) in the testing set. The calibration curve showed good concordance between the predicted and observed delirium rates among sepsis patients.
Conclusions: We developed a nomogram incorporating ten features of clinical work,especially adding factors related to nursing management. The constructed nomogram has good performance and clinical applicability and can help identify SAD patients in a timely manner for early intervention and improve neurological outcomes.
Does the Brazilian Version of the Strengthening Families Program (Famílias Fortes) Reduce Adolescent Substance Use and Improve Parental Behavior? Evidence from a 2-Year Follow-Up Study
Authors: Sanchez Zila M , Caetano Sheila C , Galvao Patricia P O , GUBERT FABIANE A , Rebouças Lidiane N , Soares-Santos Luis Eduardo , Valente Juliana Y
Published: October 2024

Blackground: The Brazilian adaptation of the Strengthening Families Program (SFP), known as Famílias Fortes (FF-BR 10-14), has demonstrated positive short-term effects on parental behavior. This study aimed to evaluate the 12- and 24-month follow-ups of the FF-BR 10-14, focusing on parental outcomes and substance use prevention.
Methods: A total of 805 adolescents (aged 10–14) and their caregivers participated in a parallel-cluster randomized controlled trial across 12 municipalities in Brazil. FF-BR 10-14, comprising seven sessions, was delivered by the Social Assistance Reference Center (SARC) staff. This study presented data collected at three time points: baseline, 12 and 24 months of follow-up. Multilevel mixed-effects models assessed the program effects on parental and adolescent outcomes (drug use and family behavior), with adjustments for sociodemographic factors.
Results: The results revealed no statistically significant differences between the groups in terms of adolescent drug use after either follow-up. However, participating in the program showed a reduction in negligent parental style (aOR 0.46, 95%CI 0.22;0.97), parental binge drinking (aOR 0.24, 95%CI 0.08; 0.74), as well as an increase in parental ability to set clear rules regarding their children's drug use (Coef 0.43, 95%CI 0.03; 0.83) and an improvement in adolescents' skills to resolve family conflicts (Coef 0.79, 95%CI 0.11; 1.46) and to manage stress (Coef 0.65, 95%CI 0.16; 1.15).
Conclusion: The Famílias Fortes program shows positive effects on mediators, such as parenting practices and adolescent coping skills, but not on the primary outcomes of adolescent substance use. These findings highlight the program's role in improving the family environment and supporting prevention efforts through intermediary behaviors.
Risk of Falls Associated with Benzodiazepine Hypnotics Use in Elderly Inpatients:A Case-Crossover Study
Authors: Chen Qiongfang , Zhang Xiaojie , Zhong Cuina , Ou Taoni , Huang Yuli , He Jingcheng
Published: October 2024

Background
Preventing falls in patients is one of the most important concerns in hospitals. This study aimed to analyse the risk of falls associated with benzodiazepine hypnotic drugs use in elderly inpatients.
Methods
We used a case-crossover design to investigate hospitalized fall patients who were older than 60 years and had taken benzodiazepine hypnotic medication from January 1st,2021 to December 31st,2023.We defined the day before the fall event as the case day (day 1) and days 2–8 before the fall event as the control days.The multivariate analysis result was reported as an odds ratio (OR) with 95% confidence interval (CI).
Results
In 70 eligible patients, the total case day was 70 days and the control days was244.Hypnotic drugs revealed a positive association with fall events (odds ratio [OR]: 1.836, 95%confidence interval [CI] = 1.029–3.275, p = 0.040). Among them, benzodiazepine receptor agonists (odds ratio [OR]:1.824, 95%confidence interval [CI] = 1.007–1.303, p = 0.047), and alprazolam (odds ratio [OR]: 1.937, 95%confidence interval [CI] = 1.021–3.673, p = 0.043), showed a positive association with fall events.
Conclusion
This study confirmed that the occurrence of falls in hospitalized elderly patients aged older than 60 years was clearly associated with the use of benzodiazepine hypnotics. Fall prevention plans should be developed and implemented for olderly inpatients taking hypnotic drugs.
Treatment outcome of ultrasound-guided hydrostatic reduction of intussusception and its associated factors among pediatric patients in a resource-limited setting
Authors: Ayana Chala Takele , Feleke Tesfahunegn H , Bazezew Anduamlak , Mehari Zelalem , Abraham Yodit , Getinet Tewodros , Belina Merga , Hailu Samuel S
Published: October 2024

Background: Ultrasound-guided hydrostatic reduction (USGHR) of intussusception was recently introduced and adopted as the initial management option for intussusception in children. Knowledge of the treatment outcome and associated factors will enhance the expansion of this technique to hospitals in Sub-Saharan Africa, where surgery largely remains the exclusive treatment strategy.
Methods: An institution-based cross-sectional study was conducted. We consecutively enrolled children with US-confirmed intussusception for whom USGHR of intussusception with normal saline was performed by a senior radiologist and/or final-year residents after ruling out contraindications. Firth’s logistic regression analysis was undertaken to determine odds ratios (ORs) and 95% confidence intervals (CIs) of factors predictive of successful outcomes.
Results: A total of 145 children with a mean age of 24 months were enrolled in the current study. The majority of patients 123 (84.8%) presented within 24 hours of symptom onset and colicky abdominal pain was the most common complaint 79 (54.5%). Ileocolic type and short-length intussusception were visualized more on ultrasound 135 (93.1) and 118 (81.4%), respectively. The overall reduction success rate was 93.1% [95% CI (89.0-97.2)]. Ten patients (13.5%) underwent surgery after a failed hydrostatic reduction with good postoperative outcomes. Reported duration of illness less than 24 hours Adjusted odds ratio (AOR) 6.77 (95% CI [1.25-30.42]) and length of intussusception less than 3.5 cm AOR 6.24 [95% CI (1.18-33.00)] were significantly associated with successful hydrostatic reduction outcomes.
Conclusion: We have found a high success rate of USGHR of intussusception in an implementation phase and a relatively low resource setup. Early presentation and short intussusception segments were favorably associated with successful outcomes.
Seasonal dynamics and geographic influences on the total ozone column in the Maceió region
Authors: de Souza Amaury , Takemura Celina M. , Özonur Deniz , de Medeiros Elias Silva , Pobocikova Ivana , Leivas Janice F. , de Oliveira-Júnior José Francisco , Rosalvo Kelvy Alencar Cardoso , Abreu Marcel Carvalho , Pansera Wagner Alessandro , Gautam Sneha
Published: October 2024

This study analyzes the Total Ozone Column (TCO) over six cities in the state of Alagoas, Brazil, with the objective of evaluating their spatial and temporal homogeneity and identifying seasonal and annual patterns over the period from 2008 to 2016. OCT is an important indicator for monitoring the ozone layer and its implications for public health, due to the role of ozone in filtering ultraviolet radiation. For the analysis, OCT data provided by satellite measurements were used, and the homogeneity of the variances was verified by means of the Bartlett test with a significance level of 95%. In addition, descriptive statistical analyses were performed to characterize the distribution of TCO values over time, and probability density functions (PDFs) were applied to identify the distribution that best fits the data. The results showed a significant homogeneity in the annual and seasonal concentrations of TCO, with an annual average of 263.24 ± 9.91 DU. The results indicated that the seasonal cycle of TCO is dominated by a biannual cycle, with two maximums and two minimums throughout the year, reflecting the influence of the Earth's orbit around the Sun and the photochemistry of ozone in the stratosphere. The highest seasonal average TCO was observed during the spring, while the lowest values occurred in the fall. The Normal distribution was identified as the one that best represents the data over the analyzed period. These patterns reflect the influence of the Brewer-Dobson Circulation, which contributes to the uniform distribution of ozone in the stratosphere, minimizing the impacts of atmospheric phenomena such as the Antarctic Polar Vortex. In conclusion, this study provides a comprehensive overview of TCO variability in six cities in Alagoas, highlighting the importance of continuous monitoring to understand atmospheric dynamics and their implications for health and the environment. The limitations of the work, such as the sensitivity of the statistical tests and the restricted geographic coverage, indicate the need for future studies to deepen the understanding of the factors that affect the distribution of ozone in the region.
The mediating role of perception of decent work in role clarity and job embeddedness among Chinese nurses: A cross-sectional study
Authors: Chen Fang , Yu Ran , Zheng Huan , Zhao Xiaoyan
Published: October 2024

Aim
To explore the relationship among clinical nurses' perception of decent work, role clarity, and job embeddedness, and to analyze the mediating effect of perception of decent work on role clarity and job embeddedness, and provide reference for improving nurses' job embeddedness level.
Background
The high turnover rate of the nursing team is not only detrimental to maintaining the stability of the team, but also to providing high-quality nursing services, which is an immeasurable loss for both patients and hospitals. As a predictor variable of turnover rate, increasing the level of job embeddedness among nurses can reduce their willingness to resign. Although there are currently studies reporting the correlation between role clarity, perception of decent work and job embeddedness, the mechanisms between the three have not been explored, which cannot provide scientific and effective theoretical support for developing targeted measures for job embeddedness.
Methods
Using convenience sampling method, 309 nurses from hospitals in Zhejiang Province China were recruited as the research subjects from July to August 2024. The General Information Questionnaire, Decent Work Perception Scale, Role Clarity Scale and Job Embeddedness Scale were used for the investigation.
Results
This study shows that the perception of decent work, role clarity, job embeddedness are all at a moderate level. The total score of job embeddedness is positively correlated with the total scores of perceived decent work and role clarity, and the perception of decent work plays a partial mediating effect between role clarity and job embeddedness, accounting for 88.1% of the total effect.
Conclusions and Implications for Nursing and Health
Policy:
According to the results of this study, to improve the job embeddedness level of clinical nurses, the hospital nursing department and head nurses in the department should explore different measures to stimulate the perception level of decent work of clinical nurses and improve their role clarity cognition, to enhance their job embeddedness level.
Electrical Carrier Transport in Thin Silicon Layers Heavy Doped With Antimony
Authors: Fedotov Alexander K. , Golovchuk Victoria I. , Fedotova Julia A. , Yurasov Dmitry V. , Przewoźnik J. , Kapusta Cz. , Novikov Alexey V. , Bushinsky Maxim V. , Fedotov Alexander S.
Published: October 2024

In the present paper we report upon the influence of heavy doping of thin Si layers with Sb on the carrier transport in the temperature range 2 < T < 300 K and magnetic field induction (B) up to 9 T. Temperature and magnetic field dependencies of the longitudinal (ρxx(T,B)/σxx(T,B)) and transversal Hall (ρxy(T,B)/σxy(T,B)) components of tensor resistivity/conductivity were measured in the samples prepared by epitaxial technology and containing Sb atoms with densities near the concentration of Mott transition 1.05×1024 ≤NSb ≤ 4.0×1024 m-3. The use of normal contributions to ρxx(T,B)/σxx(T,B) and ρxy(T,B)/σxy(T,B) made it possible to estimate the concentrations and mobilities of charge carriers (electrons) depending on Sb content NSb, concentrations of localized surface states (LSS) 1×1018 ≤NS ≤5.6×1019 m-2 and disorder parameter 1 ≤ kFl ≤ 60 of Si layers, where kF and l being the wave vector and the mean free path of electrons, respectively. It was found that the relative longitudinal MRxx(T,B) = Δρxx(T,B)/ρxx(T,0) and the transversal MRxу(T,B) = Δρxу(T,B)/ρxy(T,0) magnetoresistive effects were significantly dependent both on the type of samples (NSb below or beyond the Mott transition) and on the presence/absence of LSS in them (for locked samples with the lowest NS covered with undoped Si layer or unlocked samples with the highest NS, respectively). In unlocked (with a great content of LSS) semiconductor-type samples, the values of MRxx(T,B) and MRxу(T,B) were positive at all temperatures (which is mainly due to the Lorentzian motion of electrons in a magnetic field). In the locked semiconductor type sample and in the unlocked metal-like sample, MRxx(T,B) and MRxу(T,B) became negative either in the entire region 2 < T < 30 K (locked) or only below 7 K (unlocked) . In this case, the normal longitudinal component of the conductivity tensor in zero and non-zero magnetic field included contributions from quantum corrections to Drude carrier transport (interference and the effect of electron-electron interaction and spin-dependent contributions with times of wave functions phase breaking of electrons tφ of the order of 2 - 100 picoseconds and coherent lengths (Thouless lengths) of ~ 20 - 400 nm) and the anomalous one including different types of spin-dependent effects (due to spin-orbit and spin-spin interactions, as well as intrinsic or asymmetric skew scatterings of free electron spins on paramagnetic Sb ions).
What Neighborhood Environment Configuration Can Alleviate Depressive Symptoms in Older Adults: A Fuzzy-set Qualitative Comparative Analysis
Authors: Nan Yan , Ge Tingshuai , Jiang Quanbao
Published: October 2024

Introduction:The neighborhood is a regular living and activity space for the elderly. It is important to identify neighborhood environmental factors that can alleviate depression in the elderly to improve their health. However, existing literature does not consider the complex interdependencies among key neighborhood environmental factors.
Method:This study employs the Qualitative Comparative Analysis (QCA) method to explore how the configuration of neighborhood environmental conditions can help alleviate depressive symptoms in the elderly. The data is derived from the 2020 China Family Panel Study (CFPS) survey.
Results: The results show that three different neighborhood environment configurations can help reduce depressive symptoms in older Chinese individuals. The first configuration requires a combination of neighborhood safety, good neighborhood relations, and neighborhood assistance. The second configuration involves amalgamating optimal community facilities, high-quality neighborhood relations, and neighborhood assistance. The third configuration encompasses sound community facilities, favorable housing surroundings, a secure communal atmosphere, and advanced neighborhood assistance. Furthermore, we identify neighborhood assistance as a core condition for alleviating depressive symptoms and find that the combined effects of neighborhood safety and housing surroundings on alleviating depressive symptoms are comparable to the effect of neighborhood relationships.
Discussion:These research results deepen the current understanding of neighborhood environment configurations to alleviate depressive symptoms in older adults, offer important implications for theory and practice, and set new directions for the construction of age-friendly neighborhoods.
Feasibility Exploration on the Efficient Recovery of Chromium from a Lateritic Nickel Deposit
Authors: Xu Chen , Xiao Yiwu , Fang Mingshan , Li Lei , Feng Kai
Published: October 2024

Lateritic nickel deposits frequently contain elevated concentrations of chromium. The recovery of this fraction of the chromium resource can enhance the comprehensive utilization of resources, while simultaneously reducing the energy consumption and environmental pollution associated with smelting. The objective of this study was to investigate the feasibility and technical challenges associated with the recovery of chromium from lateritic nickel deposits from a mineralogical perspective. To this end, a process mineralogical study was conducted on a lateritic nickel deposit in Indonesia. It was discovered that chromium often occurs as chromium mineral like chromite and exhibits significant physical differences from common minerals in lateritic nickel deposits, such as limonite and serpentine, making it suitable for physical beneficiation. Consequently, the recovery rate and feasibility of chromium recovery can be predicted on the basis of determining the granularity and liberation characteristics of chromite and the occurrence state of the chromium element. This will enable a more scientific approach to be taken to the physical beneficiation process.
Psychiatric comorbidity in patients with Psoriasis: a cross sectional study from North India
Authors: Sahore Kriti , Sharma Dinesh Dutt , Lata Suman , Verma Ghanshyam , Jaswal Sumeesha
Published: October 2024

Background: Psoriasis is a psychocutaneous disorder whose prognosis is affected by psychological factors. Despite the psychological impact of the disease only 33% of the sufferers receive mental healthcare. The current study was planned to estimate the prevalence and factors affecting psychiatric co-morbidities among psoriasis patients in a tertiary care hospital.
Materials and methods: 288 consecutive patients diagnosed with psoriasis of the age 18 and above were inducted in the study. Patient were included after signing informed consent. Patient particulars were noted in the sociodemographic profile sheet and clinical profile sheet designed for the study. Diagnosis of psychiatric disorders was made according to ICD-10. If the patients are found to have anxiety or depressive disorders, the severity of the same was assessed by using appropriate scales.
Result: Anxiety was reported in 66 (22.9%) patients. Mild depression found in 23 (8.0%) patients, moderate depression occurred in 25 (8.7%) patients, and severe depression recorded in 23 (8.0%) patients. Psychiatric comorbidity was present in 74.3%, with maximum patients being diagnosed with anxiety disorder unspecified. The association between psychiatric comorbidity and higher educational level, living in joint families, in urban areas and lower middle socioeconomic status was statistically significant.
Conclusion: Our study showed the psychiatric burden to be significant in patients with psoriasis. It represents an unmet need with treatment of psychiatric comorbidity leading to improved quality of life.
Spent Mushroom Substrate (SMS) as a Potential Casing Material for Commercial Cultivation of Calocybe indica: Improved Mineral Profile and Microbial Advantages
Authors: Basir Raisa , Mahi Mahia Hossain , Ferdous Tasnimul , Gani Mohammad Abbas , Elias Sabrina M , Yesmin Sabina , Islam Md. Shafiqul , Khandakar Jebunnahar
Published: October 2024

Recent prolonged summer seasons have posed significant challenges for mushroom cultivation, underscoring the need for summer-adapted commercial varieties like Calocybe indica. Casing plays a crucial role in its cultivation, which traditionally uses loamy soil (LS). However, given the non-renewable nature of LS and the environmental concerns associated with spent mushroom substrate (SMS), our study explored SMS as a potential alternative. We examined the physio-chemical properties, and microbial flora especially bacterial composition using MALDI-TOF in both LS and SMS, along with the total yield, biological efficiency, mineral content, and total phenolic and flavonoid contents of mushrooms grown on these substrates. While most of the physio-chemical properties of SMS align with the ideal casing properties, it exhibits higher electrical conductivity (EC) and a greater C/N ratio. The dominating bacterial flora in SMS, including Bacillus, Priestia,and Lysinbacillus, contribute to the mushrooms’ temperature tolerance and facilitate nutrient uptake especially phosphorous (P). The yields and biological efficiency were significantly higher in LS, likely due to its superior mechanical support. Furthermore, the results found that element levels, especially copper (Cu), zinc (Zn), and phosphorous (P), were significantly higher in mushrooms grown on SMS except iron (Fe). Notably, phosphorus (P) levels were significantly elevated in mushrooms grown in SMS, highlighting the role of phosphorous-solubilizing bacteria in SMS. The PCA biplot results further supported these findings. Interestingly, Calocybe indica consistently exhibited higher iron (Fe) content than Pleurotus ostreatus, regardless of the casing material used. The metal bioaccumulation factors (BCF) reveal that Calocybe indica is a hyperaccumulator of potassium (K) but does not bioaccumulate manganese (Mn). It also showed a low calcium (Ca) and iron (Fe) accumulation level, suggesting a synergistic interaction between Ca and Fe. No significant difference in total phenolic and flavonoid content was observed between the LS and SMS. In conclusion, LS proved more effective in maximizing yield, while SMS emerged as a sustainable alternative with the enhanced nutritional quality of mushrooms, making it a viable option for environmentally conscious mushroom cultivation.
Novel Long Distance Free Space Quantum Secure Direct Communication for Web 3.0 Networks
Authors: Zhou Yifan , Zhou Xinlin , Li Zi Yan , Wong Yew Kee , Liang Yan Shing
Published: October 2024

With the advent of Web 3.0, the swift advancement of technology confronts an imminent threat from quantum computing. Security protocols safeguarding the integrity of Web 2.0 and Web 3.0 are growing more susceptible to both quantum attacks and sophisticated classical threats. The article introduces our novel long-distance free-space quantum secure direct communication (LF QSDC) as a method to safeguard against security breaches in both quantum and classical contexts. Differing from techniques like quantum key distribution (QKD), LF QSDC surpasses constraints by facilitating encrypted data transmission sans key exchanges, thus diminishing the inherent weaknesses of key-based systems. The distinctiveness of this attribute, coupled with its quantum mechanics base, protects against quantum computer assaults and advanced non-quantum dangers, harmonizing seamlessly with the untrustworthy tenets of the Web 3.0 age. The focus of our study is the technical design and incorporation of LF QSDC into web 3.0 network infrastructures, highlighting its efficacy for extended-range communication. LF QSDC is based on the memory DL04 protocol and enhanced with our novel Quantum-Aware Low-Density Parity Check (LDPC), Pointing, Acquisition, and Tracking (PAT) technologies, and Atmospheric Quantum Correction Algorithm (AQCA). Utilizing this method not only bolsters the security of worldwide Web 3.0 networks but also guarantees their endurance in a time when quantum and sophisticated classical threats exist simultaneously. Consequently, LF QSDC stands out as a robust security solution, well-suited for Web 3.0 systems amidst the constantly evolving digital environment.
Self-awareness and Self-control in Condom Use Among Men Who Have Sex With Men
Authors: Brum Maiara Medeiros , de Souza Lenice do Rosário , Cerqueira Ana Teresa de Abreu Ramos
Published: October 2024

Background
HIV prevention actions have always attributed the responsibility to the individual to decide to use condoms, which has been shown to be inefficient, in addition to promoting prejudice against the most vulnerable populations. This study aimed to identify, through verbal reports, the factors that influence condom use.
Methods
A total of 120 MSM were interviewed (60 without infection - G1 and 60 living with HIV - G2), users of the Domingos Alves Meira Specialized Infectious Diseases Outpatient Clinic in Botucatu, through invitations on social networks and the “snowball” technique. Data was collected using a questionnaire prepared by the researcher herself. To analyze the data, the frequencies and percentages of responses were calculated, as well as a comparison between the groups (G1 and G2) using the chi-square test. The theoretical analysis of the results was based on the concepts of self-knowledge and self-control.)
Results
Of the 120 MSM, with or without HIV infection, who were studied, 79.2% reported having had passive anal sex in the last six months and 75.0% had not used a condom with all partners. The reasons for not using condoms were trusting the partner, being more focused on the pleasure of the moment, and having only oral sex.
Conclusions
Suggestions are that the low frequency of safe sexual practices is more related to contingencies maintained by the group than to individual weaknesses or failures, highlighting the need for a better understanding of the social contexts in which these individuals find themselves.
Volatile oxidized lipids generated via metal-dependent lipid peroxidation of ω-6 PUFAs are breath biomarkers for monitoring ferroptosis in vivo
Authors: Matsuoka Yuta , Katsumata Yoshinori , Chu Po-sung , Morikawa Rei , Nakamoto Nobuhiro , Iguchi Kohta , Takahashi Ken , Kou Tadayuki , Ito Ryo , Taura Kojiro , Yazumi Shujiro , Terajima Hiroaki , Ichihara Genki , Muramoto Yuki , Sato Kazuki , Maeda Rae , Toriu Naoya , Yanagita Motoko , Tajima Masaki , Fagarasan Sidonia , Yamada Ken-ichi , Sugiura Yuki
Published: October 2024

Volatile organic compounds resulting from metabolic processes are released as biogas, and potentially can serve as noninvasive biomarkers of cellular metabolic health. During ferroptosis, a form of cell death caused by lipid peroxidation (LPO), oxidized lipid fragments can be released as biogas. We identified ω-6 PUFA-derived volatile oxidized lipids (VOLs) produced and released by cells undergoing metal-dependent LPO. Among several identified VOLs, 1-octen-3-ol and 2-pentylfuran, were validated as ferroptosis markers in in vitro cultured cells, in vivo animal models, and in human breath. We find these VOLs specifically produced in the liver during ferroptosis, in model mice of metabolic dysfunction-associated steatohepatitis (MASH) and in the exhaled air from patients with MASH. Our identification of specific VOLs released upon metal-dependent LPO, highlights their potential utilization as valuable markers for cells undergoing ferroptosis in vivo, which can be apply non-invasively to monitoring cellular health in humans.
Exploring the Lie symmetries, conservation laws, bifurcation analysis and dynamical waveform patterns of diverse exact solution to the Klein–Gordan equation
Authors: Mahmood Tariq , Alhawael Ghadah , Akram Sonia , Rahman Mati ur
Published: October 2024

This paper presents a comprehensive analysis of the (1 + 1)-dimensional Klein–Gordan equation which plays a significant role in various areas of theoretical and applied physics. The main focus of this research centers on several key areas. First, infinitesimal generators of symmetries were found by Lie symmetry invariance analysis. Then, using the adjoint representation, an ideal system was created based on the found Lie vectors. Secondly, by utilizing the analytical approach, namely the modified Sardar sub equation (MSSE) method, we systematically derive various novel soliton solution in the form of dark, bright, periodic, singular, combo, hyperbolic as well as mixed trigonometric. Finally, bifurcation analysis is performed at the system’s fixed points, revealing chaotic behavior when an external force is introduced into the dynamic system. To identify the chaotic characteristics, a range of tools, such as 3D and 2D phase plots, time series, Lyapunov exponents, and multistability analysis, are utilized. Additionally, the sensitivity analysis of the model is examined under different initial conditions. These results enhance the understanding of nonlinear wave phenomena in mathematical physics and hold potential applications across numerous scientific disciplines.