bluuebunny/crossref_metadata_2025 huggingface dataset:
INTERRELATION OF BIOLOGICAL RHYTHMS AND CIRCADIAN HORMONES PRODUCEMENT AND THEIR IMPACT ON MEDICINE USAGE
Authors: Vasko Maryna Y. , Tkachenko Iryna M. , Pavlenkova Olena V. , Pysarenko Oleg A.
Published: September 2021

The aim of the article is to establish the interrelation of human biological rhythms and circadian hormones producement as well as to determine their impact on the medicine usage.
Materials and methods: The review and latest data analysis of scientific and medical literature were performed.
Conclusions: Proceeding from the literature sources there is a firm interrelation between human biological rhythms and circadian hormones producement. Following chronotherapy principles will allow to increase effectiveness of diseases treatment, including dental ones. It will also allow to reduce dosage of prescribed medicines as well as their side effects. Prospects for a further research are to identify a clear relationship between circadian biorhythms in patients with chronic generalized periodontitis in order to increase the effectiveness of therapeutic measures.
FEATURES OF THE DEVELOPMENT OF ENTREPRENEURSHIP IN RUSSIA
Authors:   Federal State Budgetary Institution of Science ", Yakushev N.O. ,   Vologda Research Center of the Russian Academy of Sciences"
Published: September 2021

Entrepreneurship from a socio-economic perspective is the basis for the development of the economies of countries. In this article, the goal is to determine the features of the development of entrepreneurship in Russia based on the analysis of small and mediumsized, as well as high-tech businesses. To achieve this goal, the following tasks were solved: the concept of "entrepreneurship" and the criteria that determine its small and medium form were clarified; analyzed the state of entrepreneurship in Russia; the main features of the functioning of Russian entrepreneurship are highlighted. The results of the presented study contribute to the development of the theory and practice of entrepreneurship, and also have practical significance for use by the authorities and management as analytical information in the preparation of regulatory and tacticalstrategic documents for solving problems within the framework of the national project "Small and Medium-Sized Enterprises and support of individual entrepreneurial initiative".
RESEARCH OF THE ESSENCE AND COMPONENTS OF THE LOGISTICS SYSTEM
Authors:   Federal State Budgetary Educational Institution of Higher Education ", Mazanko E.V. ,   Admiral F.F. Ushakov State Maritime University", Zelenkov A.G. ,   Federal State Budgetary Educational Institution of Higher Education "Admiral F.F. Ushakov State Maritime University"
Published: September 2021

The article considers the concept of a logistics system, its relevance and significance in the modern world. To simplify and provide the most visual presentation of the material, schemes are constructed that give a general idea of the transport system, the functions of the transport and logistics system, and the basic principles of transport policy. In conclusion, the model of the transport and logistics system is described.
PROBLEMS AND CHALLENGES OF THE MODERN FISHING INDUSTRY
Authors:   Federal State Budgetary Educational Institution of Higher Education ", Koroleva K.S. ,   Saint-Petersburg State Technological Institute (Technical University)", Khodos D.V. ,   Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Technological Institute (Technical University)"
Published: September 2021

The agricultural complex is an integral part of the structure of the agro-industrial complex of the region and includes a set of enterprises that carry out homogeneous activities related to fishing, fish farming and fish processing. The development of the fisheries complex contributes not only to the economic development of a certain subject of the Federation, but also to the entire economy of the country. The article considers the main challenges and problems of the development of fisheries, taking into account the interacting role of sectoral factors and the system of relations in the food market.
IMPLEMENTATION OF DIGITAL INSTRUMENTS IN MARKETING AND OPERATING ACTIVITIES OF A HOTEL ENTERPRISE IN ORDER TO IMPROVE THE QUALITY OF PROMOTION AND PROVISION OF SERVICES
Authors:   Federal State Budgetary Educational Institution of Higher Education ", Zelezinskii A.L. ,   Saint-Petersburg State Institute of Technology (Technical University)", Arhipova O.V. ,   Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University of Economics", Aseledchenko O.M. ,   Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University of Economics"
Published: September 2021

The article discusses modern digital tools that can help hotel companies improve the quality of services provided and improve the efficiency of promotion. The authors identified the main trends in changing the behavior of the population under the influence of external and internal factors in the development of the hotel business, identified the leading digital technologies in the hotel business, presented their hierarchy, identified digital technologies as part of the hotel business product. The article also substantiates the use of digital technologies in hotel promotion and shows the effectiveness of introducing key digital tools into the activities of enterprises in the hospitality industry. It is concluded that digital technologies improve the quality of hotel services and increase hotel brand awareness. When selecting certain technologies, it is necessary to accurately determine the goals that the technology will cover, to research your target audience, the market of competitors, take into account that the hiring of competent specialists or a consulting firm will be in demand for the implementation of digital technologies in a hotel.
HISTORICAL AND EDUCATIONAL ASPECTS OF DISCOVERIES AND INVENTIONS THAT REVOLUTIONIZED MANKIND
Authors: IOANA Adrian , TUFEANU Daniela , MARCU Dragos Florin , FLOREA Bogdan , ENE Bianca Cezarina , JUGANARU Daniela Ionela , SOLEA Roxana Marina
Published: September 2021

This article presents discoveries and inventions from different periods of mankind, which played an important role in social and technological evolution. Thus, from the period of the Ancient World (prehistory - 400 AD), we present: the appearance of stone tools (which occurred in East Africa and belongs to the first hominids); pottery (appeared in 10500 BC); the development of metallurgy (began in the Middle East, around 6500 BC); the invention of the ox-drawn plow (which occurred around 4000 BC); the construction of the first pyramid in Egypt (2600 BC); the development of iron processing (as part of the development of metallurgy, it occurred around 1400 BC); modernization of papermaking technology (attributed to Tsai Lun, China, around 105 AD); Another historical period that we analyzed in terms of discoveries and innovations that revolutionized humanity was the Middle Ages (400 - 1500). Thus, from this period we presented the following discoveries and inventions: the discovery of the number zero (occurred in 520 and belongs to Indian mathematicians); woodcut printing (appeared in sixth century China); the first printed newspaper (year 700); the development of algebra (it belongs to the Greek mathematician Diophantos, 3rd century AD); gunpowder (it was discovered around 850); the establishment of the University of Bologna (made in 1088); The last period approached was the current one. From this period we presented the following discoveries: magnetism - a new form of electricity; devices controlled only by hand gestures.
DIGITAL TRANSFORMATION IN THE PROCESS OF MEDIATION
Authors:   attorney at law, Varbanova Gergana
Published: September 2021

Digital transformation is a complex and long process in which technologies are used to optimize the time and costs that are invested in various activities of public life. By using the innovations and advances of information technology, the mediation process can become faster and more transparent, facilitate access to mediation in cross-border disputes and save significant costs and time for the parties in mediation proceedings. However, the process of digital transformation cannot be an end in itself, in order to be effective, digital transformation must ensure the security of information so that each of the parties can be sure that the confidentiality of mediation proceedings is preserved even if it develops. in a digital environment. This raises a number of questions about the application of digitalization and digital transformation, which this report aims to analyze.
INTERNATIONAL REGULATION OF MEDIATION IN THE EU
Authors:   Technical University - Varna, Petrova Daniela
Published: September 2021

The future in resolving disputes in all spheres of public life lies in mediation. The aim of the author of this article is to present the current relevant European legislation on mediation and how it has found application - transposition into the legislation of EU member states. After a comparative analytical review, highlight the similarities and differences regarding the legal regulation in the individual countries and point out the good legislative practices and the progress made by the EU member states.
THE MEDIATION AS A DISCIPLINE IN THE HIGHER SCHOOLS
Authors:   University of Economics - Varna, Dimitrova Diana
Published: September 2021

The mediation is not only an alternative mean for conflict resolution, it is also a culture of communication, developing particular skills, coveted by the today's employers. The possibility of introducing mediation as a discipline in the higher schools is examined in the report. Based on the examined forms of education, offered by foreign and Bulgarian Higher Schools conclusions and summaries are made.
CONCEPT FOR DEVELOPMENT OF EMOTIONAL COMPETENCES AND CONFLICT MANAGEMENT SKILLS THROUGH MEDIATION METHODS AT THE AGE OF 3-7 YEARS
Authors:   Medical University of Varna "Prof. Dr. Paraskev Stoyanov", Ivanova Veneta
Published: September 2021

This report examines the concept of developing emotional competencies at the age of 3 - 7 years, which is the basis of an innovative for Bulgaria model for conflict management in preschools. The conclusions raise as relevant and important the question of the difference between emotional intelligence and emotional competence and how they are integrated into the educational methodology of preschool education at the moment.
MEDIATION IN THE ECUCATION
Authors:   University of Economics - Varna, Rajkova Jasmina
Published: September 2021

The report examines the application of mediation in education, as well as the relationship between education and the business environment. The aim of the present study is to present mediation as a method that builds a new model of behavior in the various social spheres. Based on the analysis, conclusions are made about the importance for the implementation of the mediation procedure in school and university, as well as the relationship with the business community. In order to achieve the set aim, the author examines the legal framework of mediation, the application of mediation in school, the possibility of upgrading knowledge in university and application in business.
KNOWLEDGE OF MEDIATION IN INTERNATIONAL BUSINESS TRAINING
Authors:   University of Economics - Varna, Alexandrova Nedyalka
Published: September 2021

The report outlines the peculiarities of international business in modern conditions such as the complexity and long-term nature of the relationship and substantiates the role of mediation in overcoming conflicts in them. The vision is expressed for opportunities for expanding the scope of mediation by introducing methods specific to it in conducting business negotiations. The need to include knowledge about mediation in international business education is substantiated.
MEDIATION AND MEDIATORS IN THE HEALTHCARE
Authors:   Institute for the State and the Law, Bulgarian Academy of Science, Zinovieva Darina
Published: September 2021

It is considered how mediation is regulated as an out-of-court way of agreement between two disputing parties in the healthcare system. For this purpose, an analysis of the current general and special laws, according to which such an agreement can be implemented, has been made. Practical issues related to problems in the implementation of the agreement are also presented, in view of the specifics of the disputes in the healthcare sector. The new legal figure of a "health mediator" is analyzed, the rights and obligations that are normatively regulated, the benefits and the needs for optimization of the regulation. The results of the analysis are summarized and specific conclusions "de lege ferenda" are proposed.
MEDIATION AND ARTIFICIAL INTELLIGENCE
Authors:   Institute for the State and the Law, Bulgarian Academy of Sciences, Yonkova Nadezhda
Published: September 2021

The report examines the benefits and risks of using artificial intelligence in mediation through the prism of the model introduced in France.
MEDIATION AS AN ALTERNATIVE TO DISCIPLINARY PROCEEDINGS
Authors:   Russe University "Angel Kanchev", Danev Vladimir
Published: September 2021

The report examines the mediation procedure in the context of disciplinary proceedings under the Labor Code. Based on an analysis of the labor law norms, as well as the existing legal doctrine and practice, the possibility for conducting the mediation procedure during and on the occasion of the disciplinary proceedings is analyzed. In conclusion, conclusions are made about the usefulness of mediation in its application in engaging disciplinary liability of an employee, on the basis of which a proposal de lege ferenda is made.
A Randomized Clinical Trial of Proton Pump Inhibitors Combined with Traditional Chinese Medicine in the Treatment of Laryngopharyngeal Reflux Disease
Authors: Pei Feng , Hu Wei-Jia , Mao Yi-Nan , Zhao Yu-Liang
Published: September 2021

Background: To explore whether combined with TCM based on classical proton pump inhibitors (PPIs) therapy can achieve better efficacy for patients with laryngopharyngeal reflux disease. Methods: There were 150 laryngopharyngeal reflux patients enrolled and divided into
three groups randomly, with 50 cases in each group. Patients in group A were treated with the proton pump inhibitor (PPI) lansoprazole. Patients in group B were treated with lansoprazole combined with Banxia Houpu decoction, and patients in group C were treated with acupuncture treatments
and a combination of Chinese and Western medicine. The reflux symptom index (RSI), reflux finding score (RFS), and quality of life (36-item short form health survey questionnaire) were assessed before and 4 and 8 weeks after treatment. Results: The RSI and RFS scores of the three groups
were significantly reduced after treatment (P < 0.001). In group B and C, they were lower than in group A at 8 weeks (P < 0.01). The SF-36 score of 3 groups increased after treatment. At both 4 and 8 weeks (P < 0.001), and patients in groups B and C scored higher than patients in
group A (P < 0.001). The total effective rate of group B and group C was higher than that of group A (P < 0.05). Conclusion: All three treatments have therapeutic effects on the disease, but the efficacy of a PPI alone is not as good as the combined treatments' efficacies. Moreover,
PPI combined with Banxia Houpu decoction and/or acupuncture treatment substantially affects life improvement.
The Effectiveness and Safety of Chemical Drugs Combined with Acupuncture for Alzheimer's Disease: A Systematic Review and Meta-Analysis
Authors: Yu Shenghua , Liu Hongjie , Xu Li , Zhang Yan , Ma Yan , Zheng Hong , Tian Caijun , Zhang Zhe
Published: September 2021

Introduction: Acupuncture has been applied with chemical drugs to treat Alzheimer's disease (AD) in the clinic. Whether such combination is effective and safe should be studied although it is recommended by some researchers.
 Methods: To explore the effectiveness
and safety of acupuncture combined with chemical drugs for AD, databases like PubMed, Web of Science were searched to retrieve randomized controlled trials (RCTs) on AD treated with acupuncture and chemical drugs to perform meta-analysis. The risk of bias in each study was assessed using the
Cochrane risk of bias tool. Meta- analysis was performed using RevMan 5.3.
 Results: Five studies were included in which only donepezil combined with acupuncture was evaluated. Acupuncture combined with donepezil showed a significant difference in effectiveness rate [RR=1.45,
95% CI (1.19, 1.77), P =0.0002] compared with donepezil. On the comparison of mini-mental state examination (MMSE) score and Alzheimer's disease assessment scale cognitive subscale (ADAS-Cog) score there was no difference. However, after one trial with severe AD patients was removed,
acupuncture combined with donepezil showed better effect than donepezil alone.
 Conclusion: Acupuncture combined with donepezil could work on AD at the early stage or being mild, implying that acupuncture could be a complementary therapy for AD at the early stage or being
mild. Besides, scalp acupuncture seems to be more effective on improving cognitive function. However, this conclusion must be considered cautiously, given the small sample size and lack of trials with high quality. Therefore, more high-quality, multicenter, prospective RCTs with large sample
sizes are needed to further clarify the effect of acupuncture combined with chemical drugs for AD.
Strategi Coping Stress pada Ibu Hamil di Masa Pendemi Covid 19
Authors: Rofiqoch Isnaeni , Dewi Sawitri , Yuliani Diah Atmarina
Published: September 2021

Pregnancy is a time of determining the welfare and development of the fetus in the womb. During pregnancy many women experience psychological changes, so a method is needed to reduce the problems that arise during the pregnancy process, this method is called a coping strategy. The purpose of this study was to identify coping strategies for stress in pregnant women during the COVID-19 pandemic in the South Purwokerto Community Health Center, Banyumas Regency. This research is a qualitative research with a phenomenological approach. The data collection method in this research is carried out by in-depth interviews. This research is expected to be able to dig up information about what psychological problems are faced by pregnant women and how they solve the problems faced during the covid 19 pandemic. The main informant in the meantime is mother pregnant, supporting informants are midwives and family members (husband, mother or sibling) as triangulation. The results of this study stress coping strategies during pregnancy are needed to reduce problems during pregnancy. This strategy for coping with stress during pregnancy during the COVID-19 pandemic is carried out with the mechanism of Emotional Focused Coping and Problem Facus Coping. Although the Emotional Focused Coping mechanism is more dominantly used by pregnant women because pregnant women are women where women prioritize feelings over logic.
”Meillä ei ole politiikkaa valtionavustuksissa!”
Authors: Jakonen Olli , Sokka Sakarias
Published: September 2021

Valtionavustustoiminta on olennainen osa suomalaista yhteiskuntapolitiikkaa ja valtionhallinnon ohjausjärjestelmää. Avustamista toimeenpanevat ministeriöt, tulosohjatut virastot sekä muut asiantuntijaorganisaatiot. Artikkelimme tutkii kulttuurihallinnon virkakunnan vallankäyttöä opetus- ja kulttuuriministeriön (OKM) valtionavustuspolitiikassa. Ymmärrämme kulttuurihallinnon ohjausvälineineen merkittävänä valtaa käyttävänä organisaatiorakenteena. Tarkastelu pohjautuu arviointitutkimukseen OKM:n tulosohjaaman asiantuntijaviraston Taiteen edistämiskeskuksen (Taike) valtionavustusprosessista. Artikkelimme on tapaustutkimus, jossa kuvaamme kulttuuripolitiikan toimeenpanorakenteet ja analysoimme OKM:n ja Taiken ministeriö- ja virastotason yhteistoimintana toteuttamaa valtionavustustoimintaa. Keskeinen aineistomme koostuu kulttuurihallinnon viranhaltijoiden haastatteluista. Tulkitsemme viranhaltijoita aktiivisina toimijoina ja nostamme esiin vallan- käytön mekanismeja. Politiikan ohjausvälineiden sekä valtionavustusprosessin puitteissa tarkastelemme viranhaltijoiden vallankäyttöä sekä keskinäisenä kamppailuna että suhteena poliittiseen päätöksentekoon ja avustuksia hakeviin järjestöihin. Nykyinen kulttuuripolitiikan ohjausjärjestelmä sisältää toimintatapoja julkishallinnon paradigmoista. Yksittäisillä viranhaltijoilla on paras tieto järjestelmän eri osista ja mahdollisuuksia vaikuttaa kulttuuripoliittisen järjestelmän toimintaan useilla tavoilla aina strategisesta suunnittelusta ja politiikan valmisteluvaiheesta arviointiohjaukseen asti. Lopputuloksena esitämme kuusi viranhaltijoiden valtaa ilmentävää teemakokonaisuutta. Valtionavustustoiminta ja siihen kytkeytyvä ohjaus ei ole lineaarinen hallinnollinen prosessi, vaan jatkuvaa, syklistä poliittista toimintaa, joka on kytköksissä erilaisiin julkishallinnon vaiheisiin ja tavoitteisiin. Valtasuhteet eivät myöskään ole yksisuuntaisia, vaan esimerkiksi kansalaisyhteiskunta on Suomessa perinteisesti vaikuttanut ja vaikuttaa edelleen hallinnon ratkaisuihin.
Taloudellisen tuottavuuden tutkimisesta
Authors: Lähdemäki Sakari
Published: September 2021

Artikkeli on tehty KTT Sakari Lähdemäen 5.3.2021 Turun yliopistossa pidetyn väitöstilaisuuden lektiosta. Väitöskirjan erillisiä artikkeleja yhdistävä teema on taloudellinen tuottavuus. Teoksen nimi on Essays on Economic Productivity.
Ruotsista tuli pakkoruotsia
Authors: Oittinen Vesa
Published: September 2021

Kirja-arvostelu
Prüfvorgaben in laufender Produktion umgesetzt
Authors: Gerland Gerrit , Rosenkranz Cora
Published: September 2021

Effizienz und Präzision sind in der Automobilproduktion entscheidende Erfolgsfaktoren. Folgerichtig sind am Montageband jeder Arbeitsschritt und jeder Handgriff sekundengenau getaktet. Wie ein deutscher Sportwagenhersteller dennoch eine neue Prüfrichtlinie einführen konnte, zeigt der folgende Beitrag.
Questões de conservação preventiva debatidas na Conferência Internacional de Madrid de 1934 e sua influência no projeto de ampliação do Museu Nacional de Arte Antiga de Lisboa (1935-1945)
Authors: Moura Soares Clara
Published: September 2021

A Conferência Internacional de Museus que teve lugar em Madrid, em 1934, representou um marco decisivo na afirmação do museu moderno desejado para o século XX. Ali se trataram, pela voz dos mais conceituados especialistas internacionais, múltiplas problemáticas relacionadas com a museografia e com a arquitetura de museus. Neste estudo, colocamos o enfoque nas questões ligadas ao âmbito da conservação preventiva, cujo termo apenas seria formalmente estabelecido, em 1978, por Garry Thomson. Integrar a Conferência de Madrid na perspetiva histórica da conservação preventiva é um dos contributos deste trabalho, bem como avaliar, através de documentação arquivística, os seus efeitos sobre o projeto de ampliação do Museu Nacional de Arte Antiga, em Lisboa, então em elaboração. Instalado num palácio seiscentista, o histórico museu que o seu diretor desejava moderno, tornou-se num importante caso de estudo para a museologia, museografia e arquitetura museal da época, com repercussões internacionais.
Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
Authors: Liu Yi , Luo Puying , Fu Yang , Hao Tianxin , Liu Xuan , Ding Qiuping , Peng Yiyuan
Published: September 2021

Great progress has been made in the tandem annulation of enynes in the past few years. This review only presents the corresponding reactions of 1,3-enyne structural motifs to provide the functionalized pyridine and pyrrole derivatives. The functionalization reactions cover iodination, bromination, trifluoromethylation, azidation, carbonylation, arylation, alkylation, selenylation, sulfenylation, amidation, esterification, and hydroxylation. We also briefly introduce the applications of the products and the reaction mechanisms for the synthesis of corresponding N-heterocycles.
Din Eğitimci ve Öğreticilerinin Mesleki Tutum ile Tükenmişlik Düzeyleri
Authors: ABANOZ Süleyman
Published: September 2021

Son yıllarda dünyada ve Türkiye’de dine ilgi artarak devam etmektedir. Tüm dünyada etkili olan, kurumsal dinlerin özünü yaşama iddiasındaki grupların çoğalması, dinî söylemlerin Türkiye ve dünya siyasetinde artması ve ortaya çıkan yeni dinî hareketler bu duruma örnek oluşturmaktadır. Bunun yanında Türkiye’de, halkın bu yöndeki talepleri ve siyasi iktidarın söz ve eylemlerinin de etkisiyle dine, dinî kurum ve mesleklere ilgi oldukça artmıştır. Din görevlisinin mesleğiyle ilgili geçirdiği yaşantılarla oluşan mesleki tutumunun duygusal, zihinsel ve davranışsal boyutları bulunur. Mesleği sevme ya da sevmeme gibi duygular, mesleki tutumunun duygusal boyutunu oluşturur. Meslekle ilgili düşünce ve bilgileri mesleki tutumun bilişsel (zihinsel) boyutunu meydana getirmektedir. Mesleki tutumun davranış boyutu ise, duygusal ve bilişsel boyutlarına uygun olarak yapılan mesleki faaliyetler ve işlerdir. Tükenmişliğin örgüt ve iş boyutu, kavramın oluşumu ve gelişimi açısından önem taşımaktadır. Çünkü insanlar hayatlarının büyük bir kısmını işyerlerinde geçirmektedirler. İş yaşantılarını, örgüt yapılarını, istemeden de olsa aile ve ev yaşantılarına yansıtmaktadırlar. İş yükü ağırlığı, işin niteliği, çalışma arkadaşlığı ilişkileri, iletişim ve bunun yanı sıra örgütün yönetim ve organizasyon yapısı, uygulanan strateji ve politikalar, yönetici uygulamaları ve yaptırımları, kanunlar, yasalar, yönetmelikler bireysel boyutta tükenmişlik sendromunun oluşuma zemin hazırlayabilmektedir. Bu çalışmada her biri Türkiye’nin farklı bölgelerinde yer alan yedi büyükşehirdeki dinî yükseköğretim kurumlarında, Millî Eğitim Bakanlığında ve Diyanet İşleri Başkanlığında çeşitli unvanlarda çalışanların mesleki tutum ve tükenmişlik düzeyleri incelenmiştir. Veri toplama aracı olarak demografik bilgiler, mesleki tutum ve mesleki tükenmişlik ölçeklerini içeren anket uygulanmıştır. Çalışma kapsamında 282 akademisyen, 1605 öğretmen ve 1775 din görevlisi olmak üzere toplam 3662 katılımcının anketi geçerli kabul edilmiştir. Çalışma sonucunda elde edilen veriler SPSS 23,0 istatistik programıyla incelenmiştir. Çalışmada anlamlılık düzeyi p<0,05 olarak belirlenmiştir. Analiz sonucunda mesleki tükenmişlik ve mesleki tutum arasında ters yönlü yüksek düzeyde bir korelasyon görülmüştür. Bunun yanında medeni durum, yaş, hizmet süresi, cinsiyet, yaşanılan şehir ve eğitim seviyesi gibi değişkenler ile mesleki tutum ve tükenmişlik arasında kurumdan kuruma değişmekle birlikte anlamlı bir ilişki olduğu tespit edilmiştir. Yerleşim yeri, unvan ve mesleği seçme nedeninin ise mesleki tutum ve tükenmişlik açısından tüm kurumlarda benzer bir etkiye sahip olduğu görülmüştür. Ulaşılan sonuçlar araştırmacı tarafından yorumlanmış, ayrıca sonuçlardan hareketle bazı önerilerde bulunulmuştur.
The Comparison of 25-Hydroxyvitamin D3 between Patients With and Without Cervical Cancer
Authors: Suardi Dodi , Renita Feny , Kurniadi Andi , Pramatirta Akhmad Yogi , Judistiani Raden Tina Dewi , Hidayat Yudi Mulyana , Setiabudiawan Budi
Published: September 2021

BACKGROUND: Vitamin D was currently believed to have effects on numerous cancer pathogenic processes.

AIM: This study was to assess the correlation of Vitamin D serum level in women with carcinoma cervix and also evaluate the effect of carcinoma cervix on the Vitamin D serum.

METHODS: This was an observational with a cross-sectional study. Participants were women with cervical cancer who have not received any treatment, presented to the Oncology Clinic of the Obstetrics and Gynecology Department of Dr. Hasan Sadikin General Hospital, and women without cervical cancer. The level of Vitamin D3 was analyzed in the Serology Laboratory of Clinical Pathology Department of Dr. Hasan Sadikin General Hospital.

RESULTS: There were 113 participants consisted of 58 women with cervical cancer and 55 healthy women. Mean levels of Vitamin D3 were significantly lower in cervical cancer group than non-cervical cancer group (26.74 ± 13.166 vs. 32.16±14.86, p = 0.022).

CONCLUSION: The level of Vitamin D3 was found to be significantly higher in the non-cervical cancer group than cervical cancer group.
Une expérimentation low-tech de l’autonomie énergétique et alimentaire
Authors: Grojnowski Jérémie
Published: September 2021

Conçue et bâtie par un ingénieur reconverti à l’agriculture biologique, la ferme Tournesol est à la fois une terre nourricière et un lieu d’expérimentation foisonnant d’inventions low-tech dédiées à un projet d’autonomie énergétique et alimentaire. Jérémie Grojnowski 1 s’appuie ici sur l’« écosophie » de Félix Guattari pour appréhender ce lieu comme un système de l’autonomie dans lequel se jouent des tensions et hybridations qui témoignent d’une vision expérimentale de l’écologie, guidée dans le même temps par un esprit pragmatique.
Cultiver de nouvelles possibilités de vivre
Authors: Dréau Victorine
Published: September 2021

Par différentes pratiques agricoles, la communauté du quartier Pinares de Oriente, située à la périphérie de Medellin, en Colombie, œuvre à la transformation du territoire en s’opposant aux dynamiques néolibérales et à l’homogénéisation de l’habitat urbain et périurbain. Au travers de ce récit collectif, les représentantes de la communauté nous éclairent sur cette portée transformatrice et nous dévoilent la manière dont ces expériences collectives génèrent de nouvelles modalités de subjectivité par la réinvention de rapports sociaux, la récupération de la mémoire collective, l’échange de savoir-faire traditionnels ou encore par la création d’imaginaires paysagers et urbains. De façon expérimentale, elles construisent ainsi de nouvelles références existentielles.
Une organisation sans but lucratif peut-elle perdre sa légitimité en sortant d’un groupe stratégique ? Le cas de France Business School
Authors: Bylykbashi Suela , Assala Khalil , Bouraoui Nassiba , Sahut Jean-Michel , Stephan Sylvie
Published: September 2021

L’objectif de cet article est de caractériser les conséquences sur la légitimité d’une sortie d’un groupe stratégique dans le monde de l’enseignement supérieur. Cette recherche se fonde sur l’étude du cas unique de France Business School (fBS). A travers une analyse d’une base d’articles, complétée par une démarche d’entretiens semi-directifs, ce travail analyse le processus de déconstruction de la légitimité de fBS issu de la sortie du groupe stratégique des grandes écoles de management masterisées. Il apporte ainsi un éclairage sur l’interaction entre les dimensions cognitive, morale et pragmatique de la légitimité pour expliquer l’échec de fBS.
Sous-traiter la prise en charge des élèves « méritant·es »
Authors: Cornand Renaud , Pavie Alice , Richard-Bossez Ariane
Published: September 2021

Les dispositifs dits « d’ouverture sociale » destinés à lutter contre les inégalités scolaires visent à promouvoir les élèves de milieu populaire considéré·es comme plus méritant·es, plutôt qu’à donner à tou·tes les conditions d’une scolarité épanouie. Elles mobilisent des acteurs souvent bénévoles et extérieurs à l’institution scolaire dans le cadre de pratiques éducatives hétérogènes et soumises à un contrôle très limité.
Après 40 ans de politiques « égalité » en éducation, avons-nous enfin abouti à la convention ultime ?
Authors: Collet Isabelle
Published: September 2021

Comment expliquer qu’en 40 ans de politiques publiques françaises visant l’égalité F/H en éducation, les évolutions soient si lentes et que la montagne semble parfois accoucher d’une souris ? Les documents officiels et institutionnels constituent à présent une littérature très fournie qu’on peut analyser pour obtenir un début de réponse à cette question. Isabelle Collet montre, à travers l’évolution des contenus de ce corpus, les obstacles qui peuvent entraver la réalisation d’une « égalité réelle » en éducation : ambiguïtés et angles morts de la mixité, reculs face aux forces de la réaction, évolution laborieuse des formations enseignantes, limites de la lutte contre les stéréotypes, mais aussi, plus fondamentalement, universalisme républicain «  gender-blind  ».
Limosilactobacillus reuteri ATCC 6475 metabolites upregulate the serotonin transporter in the intestinal epithelium
Authors: Engevik M. , Ruan W. , Visuthranukul C. , Shi Z. , Engevik K.A. , Engevik A.C. , Fultz R. , Schady D.A. , Spinler J.K. , Versalovic J.
Published: September 2021

The serotonin transporter (SERT) readily takes up serotonin (5-HT), thereby regulating the availability of 5-HT within the intestine. In the absence of SERT, 5-HT remains in the interstitial space and has the potential to aberrantly activate the many 5-HT receptors distributed on the epithelium, immune cells and enteric neurons. Perturbation of SERT is common in many gastrointestinal disorders as well as mouse models of colitis. Select commensal microbes regulate intestinal SERT levels, but the mechanism of this regulation is poorly understood. Additionally, ethanol upregulates SERT in the brain and dendritic cells, but its effects in the intestine have never been examined. We report that the intestinal commensal microbe Limosilactobacillus (previously classified as Lactobacillus) reuteri ATCC PTA 6475 secretes 83.4 mM ethanol. Consistent with the activity of L. reuteri alcohol dehydrogenases, we found that L. reuteri tolerated various levels of ethanol. Application of L. reuteri conditioned media or exogenous ethanol to human colonic T84 cells was found to upregulate SERT at the level of mRNA. A 4-(4-(dimethylamino) phenyl)-1-methylpyridinium (APP+) uptake assay confirmed the functional activity of SERT. These findings were mirrored in mouse colonic organoids, where L. reuteri metabolites and ethanol were found to upregulate SERT at the apical membrane. Finally, in a trinitrobenzene sulphonic acid model of acute colitis, we observed that mice treated with L. reuteri maintained SERT at the colon membrane compared with mice receiving phosphate buffered saline vehicle control. These data suggest that L. reuteri metabolites, including ethanol, can upregulate SERT and may be beneficial for maintaining intestinal homeostasis with respect to serotonin signalling.
Physical activities of jockeys during a working week
Authors: Legg K.A. , Cochrane D.J. , Gee E.K. , Rogers C.W.
Published: September 2021

Horse racing and training is a physically demanding sport. The aims of this study were to quantify the physical activities of jockeys during a working week and to investigate self-reported fall and injury incidence rates of jockeys at work. A daily workload diary examining workday and physical activities was emailed to all jockeys licensed to ride in a race in New Zealand in 2020. Sixty-three jockeys (25 apprentices, 33 professional and 5 amateur riders) began the diary, representing 38% of the licensed population of jockeys in New Zealand. Jockeys worked a median of 44 (interquartile range (IQR) 33-57) hours, 6-days per week. A median of 7 (IQR 6-9) horses were ridden per day, comprising 58% of work time, with 11 (IQR 7-15) hours per week spent at training pace. Elite jockeys (high performance in the premiership table) spent more time riding in races (1.1, IQR 0.7-1.2 hours per week) than non-elite jockeys (0.0, 0.0-0.4, P=0.01), with 29% (IQR 0-54%) of their weekly rides as race rides. Extra physical training was conducted by 72% of jockeys, which consisted mainly of low intensity exercise such as pleasure riding (56%) and walking (43%). Falls during morning exercise work were recorded by 87% of respondents, 40% of which had sustained an injury in the previous 12 months. Jockeys who participated in extra physical training had higher fall incidence rates per 1000 horses ridden in morning exercise work (3.5, 95% confidence interval (CI) 3.1-3.9, P=0.002) but lower fall incidence rate in race riding (2.1, 95% CI 1.5-2.8, P<0.001) than jockeys who did no extra training (2.5, 95% CI 2.0-3.0 and 5.9, 95% CI 3.8-9.0). Elite jockeys experience a level of specific race exercise which is lacking in the other jockeys.
The impact of time delay and angiogenesis in a tumor model
Authors: Wang Zejia , Zhou Haihua , Song Huijuan
Published: September 2021

We consider a free boundary tumor model under the presence of angiogenesis and time delays in the process of proliferation, in which the cell location is incorporated. It is assumed that the tumor attracts blood vessels at a rate proportional to \begin{document}$ \alpha $\end{document}, and a parameter \begin{document}$ \mu $\end{document} is proportional to the 'aggressiveness' of the tumor. In this paper, we first prove that there exists a unique radially symmetric stationary solution \begin{document}$ \left(\sigma_{*}, p_{*}, R_{*}\right) $\end{document} for all positive \begin{document}$ \alpha $\end{document}, \begin{document}$ \mu $\end{document}. Then a threshold value \begin{document}$ \mu_\ast $\end{document} is found such that the radially symmetric stationary solution is linearly stable if \begin{document}$ \mu<\mu_\ast $\end{document} and linearly unstable if \begin{document}$ \mu>\mu_\ast $\end{document}. Our results indicate that the increase of the angiogenesis parameter \begin{document}$ \alpha $\end{document} would result in the reduction of the threshold value \begin{document}$ \mu_\ast $\end{document}, adding the time delay would not alter the threshold value \begin{document}$ \mu_\ast $\end{document}, but would result in a larger stationary tumor, and the larger the tumor aggressiveness parameter \begin{document}$ \mu $\end{document} is, the greater impact of time delay would have on the size of the stationary tumor.
Boundary layer solutions to singularly perturbed quasilinear systems
Authors: Butuzov Valentin , Nefedov Nikolay , Omel'chenko Oleh , Recke Lutz
Published: September 2021

We consider weak boundary layer solutions to the singularly perturbed ODE systems of the type \begin{document}$ \varepsilon^2\left(A(x, u(x), \varepsilon)u'(x)\right)' = f(x, u(x), \varepsilon) $\end{document}. The new features are that we do not consider one scalar equation, but systems, that the systems are allowed to be quasilinear, and that the systems are spatially non-smooth. Although the results about existence, asymptotic behavior, local uniqueness and stability of boundary layer solutions are similar to those known for semilinear, scalar and smooth problems, there are at least three essential differences. First, the asymptotic convergence rates valid for smooth problems are not true anymore, in general, in the non-smooth case. Second, a specific local uniqueness condition from the scalar case is not sufficient anymore in the vectorial case. And third, the monotonicity condition, which is sufficient for stability of boundary layers in the scalar case, must be adjusted to the vectorial case.
A study of disproportionately affected populations by race/ethnicity during the SARS-CoV-2 pandemic using multi-population SEIR modeling and ensemble data assimilation
Authors: Fleurantin Emmanuel , Sampson Christian , Maes Daniel Paul , Bennett Justin , Fernandes-Nunez Tayler , Marx Sophia , Evensen Geir
Published: September 2021

The disparity in the impact of COVID-19 on minority populations in the United States has been well established in the available data on deaths, case counts, and adverse outcomes. However, critical metrics used by public health officials and epidemiologists, such as a time dependent viral reproductive number (\begin{document}$ R_t $\end{document}), can be hard to calculate from this data especially for individual populations. Furthermore, disparities in the availability of testing, record keeping infrastructure, or government funding in disadvantaged populations can produce incomplete data sets. In this work, we apply ensemble data assimilation techniques which optimally combine model and data to produce a more complete data set providing better estimates of the critical metrics used by public health officials and epidemiologists. We employ a multi-population SEIR (Susceptible, Exposed, Infected and Recovered) model with a time dependent reproductive number and age stratified contact rate matrix for each population. We assimilate the daily death data for populations separated by ethnic/racial groupings using a technique called Ensemble Smoothing with Multiple Data Assimilation (ESMDA) to estimate model parameters and produce an \begin{document}$R_t(n)$\end{document} for the \begin{document}$n^{th}$\end{document} population. We do this with three distinct approaches, (1) using the same contact matrices and prior \begin{document}$R_t(n)$\end{document} for each population, (2) assigning contact matrices with increased contact rates for working age and older adults to populations experiencing disparity and (3) as in (2) but with a time-continuous update to \begin{document}$R_t(n)$\end{document}. We make a study of 9 U.S. states and the District of Columbia providing a complete time series of the pandemic in each and, in some cases, identifying disparities not otherwise evident in the aggregate statistics.
Solving a fractional programming problem in a commercial bank
Authors: Chuluunbaatar Ankhbayar , Rentsen Enkhbat
Published: September 2021

We formulate a new optimization problem which arises in the Bank Asset and Liability Management (ALM). The problem is a fractional programming which belongs to a class of global optimization. Most of optimization problems in the Bank Asset and Liability Management are return maximization or risk minimization problems. For solving the fractional programming problem, we propose curvilinear multi-start algorithm which finds the best local solutions to the problem. Numerical results are given based on the balance sheets of 5 commercial banks of Mongolia.
Further results on permutation polynomials and complete permutation polynomials over finite fields
Authors: Liu Qian ,   College of Computer and Data Science, Fuzhou University, Fuzhou 350116, China, Xie Jianrui , Liu Ximeng , Zou Jian ,   Key Laboratory of Information Security of Network Systems, Fuzhou University, Fuzhou 350116, China,   imec-COSIC, KU Leuven, Leuven, Belgium
Published: September 2021

In this paper, by employing the AGW criterion and determining the number of solutions to some equations over finite fields, we further investigate nine classes of permutation polynomials over $ \mathbb{F}_{p^n} $ with the form $ (x^{p^m}-x+\delta)^{s_1}+(x^{p^m}-x+\delta)^{s_2}+x $ and propose five classes of complete permutation polynomials over $ \mathbb{F}_{p^{2m}} $ with the form $ ax^{p^m}+bx+h(x^{p^m}-x) $.
Research on airport multi-objective optimization of stand allocation based on simulated annealing algorithm
Authors: Zhao Ningning ,   College of Air Traffic Management, CAUC, Tianjin 300300, China, Duan Mingming
Published: September 2021

In this study, a multi-objective optimized mathematical model of stand pre-allocation is constructed with the shortest travel distance for passengers, the lowest cost for airlines and the efficiency of stand usage as the overall objectives. The actual data of 12 flights at Lanzhou Zhongchuan Airport are analyzed by application and solved by simulated annealing algorithm. The results of the study show that the total objective function of the constructed model allocation scheme is reduced by 40.67% compared with the actual allocation scheme of the airport, and the distance traveled by passengers is reduced by a total of 4512 steps, while one stand is saved and the efficiency of stand use is increased by 31%, in addition to the reduction of airline cost by 300 RMB. In summary, the model constructed in the study has a high practical application value and is expected to be used for airport stand pre-allocation decision in the future.
Sharp Strichartz estimates for some variable coefficient Schrödinger operators on $ \mathbb{R}\times\mathbb{T}^2 $
Authors: Federico Serena ,   Department of Mathematics: Analysis Logic and Discrete Mathematics, Ghent University, Krijgslaan 281, Ghent, B 9000, Belgium, Staffilani Gigliola ,   Department of Mathematics Massachusetts Institute of Technology, 77 Massachusetts Ave, MA 02139-4307, USA
Published: September 2021

In the first part of the paper we continue the study of solutions to Schrödinger equations with a time singularity in the dispersive relation and in the periodic setting. In the second we show that if the Schrödinger operator involves a Laplace operator with variable coefficients with a particular dependence on the space variables, then one can prove Strichartz estimates at the same regularity as that needed for constant coefficients. Our work presents a two dimensional analysis, but we expect that with the obvious adjustments similar results are available in higher dimensions.
Perceived crowding and physical distance rules: a national account perspective
Authors: Meligi Andrea Karim El ,   Department of Humanities and Social Sciences, University of Sassari, Via Roma 151, 07100 Sassari, Italy, Carboni Donatella , Garau Giorgio
Published: September 2021

Policies concerning the sustainable tourism are fundamentally addressed to the environmental protection and to minimize the anthropogenic impact when exploiting beaches, archeological sites and other tourist attractions. In this paper, we propose a subjective measure, namely the Perceived factor, in order to take into account the more general dimension of the social factor in the assessment of the Tourism Carrying Capacity (TCC) measures. The analysis evaluates the employment impact of the perceived crowding by using data resulting from a survey conducted in the Asinara National Park. In this respect, a macroeconomic analysis is presented by using a SAM scheme developed at a local level, based on four municipalities representing a potential gravitational area of tourists visiting the Asinara National Park. Afterward, a SAM-based model combined with the sustainability measures is proposed to compute the employment loss due to the Perceived factor.
Nuevos datos sobre Nomius pygmaeus (Dejean, 1831) (Coleoptera: Carabidae) en la península Ibérica
Authors: Ortuño Vicente M.
Published: September 2021

Se ofrece un nuevo registro de Nomius pygmaeus (Dejean, 1831) para la fauna ibérica, el tercero desde que hace un cuarto de siglo se aportaron las dos primeras citas para la península. Las condiciones de colecta de estos especímenes son acordes con los hábitos pirófilos descritos para esta especie. Se discuten algunos aspectos que pueden estar relacionados con la amplia distribución (holártica) y la rareza de N. pygmaeus, en especial en ámbito paleártico.
Hacia una sociedad igualitaria: valores familiares y género en los jóvenes en Alemania, Noruega y España
Authors: Moreno Mínguez Almudena
Published: September 2021

El objetivo de este artículo es analizar cómo inciden las variables socio-demográficas en los valores familiares y laborales entre los jóvenes de 18 a 35 años en Alemania, Noruega y España, países con diferentes modelos familiares, Estados de bienestar y roles de género. El artículo trata, por tanto, de cubrir el vacío existente en la literatura sobre los valores familiares y de género entre los jóvenes, tratando de ir más allá de la perspectiva dualista existente en estos estudios. El análisis está basado en los datos procedentes de la Encuesta Social Europea correspondiente a 2010, la cual contiene preguntas relativas a los valores familiares y la conciliación laboral y familiar. Se ha aplicado un análisis de regresión logística para estimar el efecto de variables socio-demográficas como el género, la educación o la situación laboral en los valores familiares de los jóvenes desde una perspectiva comparada.
Los resultados evidencian que los valores familiares tradicionales están más enraizados entre los jóvenes en los países del sur de Europa que en el norte de Europa. También se ha observado un efecto significativo de la educación en aquellos países donde la familia tradicional está más arraigada, mientras que el desempleo tiene un efecto inverso en los valores tradicionales. Estos hallazgos aportan progresos innovadores a los estudios de juventud y familia desde una perspectiva comparada, además de ser útiles para orientar el diseño de políticas familiares destinadas a favorecer la transición actitudinal hacia modelos de familia igualitarios con potenciales efectos positivos en la fecundidad y la igualdad de género.