bluuebunny/crossref_metadata_2025 huggingface dataset:
Physical model of near-Earth asteroid (1917) Cuyo from ground-based optical and thermal-IR observations
Authors: Rożek A. , Lowry S. C. , Rozitis B. , Green S. F. , Snodgrass C. , Weissman P. R. , Fitzsimmons A. , Hicks M. D. , Lawrence K. J. , Duddy S. R. , Wolters S. D. , Roberts-Borsani G. , Behrend R. , Manzini F.
Published: June 2019

Context.The near-Earth asteroid (1917) Cuyo was subject to radar and light curve observations during a close approach in 1989, and observed up until 2008. It was selected as one of our ESO Large Programme targets, aimed at observational detections of the Yarkovsky-O’Keefe-Radzievskii-Paddack (YORP) effect through long-term light curve monitoring and physical modelling of near-Earth asteroids.

Aims.We aim to constrain the physical properties of Cuyo: shape, spin-state, and spectroscopic and thermo-physical properties of the surface.

Methods.We acquired photometric light curves of Cuyo spanning the period between 2010 and 2013, which we combined with published light curves from 1989 to 2008. Our thermal-infrared observations were obtained in 2011. Rotationally resolved optical spectroscopy data were acquired in 2011 and combined with all available published spectra to investigate any surface material variegation.

Results.We developed a convex light curve-inversion shape of Cuyo that suggests the presence of an equatorial ridge, typical for an evolved system close to shedding mass due to fast rotation. We determine limits of YORP strength through light curve-based spin-state modelling, including both negative and positive acceleration values, between − 0.7 × 10−8and 1.7 × 10−8rad day−2. Thermo-physical modelling with the ATPM provides constraints on the geometric albedo,pV= 0.24 ± 0.07, the effective diameter,Deff= 3.15 ± 0.08km, the thermal inertia, Γ = 44 ± 9 J m−2s−1∕2K−1, and a roughness fraction of 0.52  ±  0.26. This enabled a YORP strength prediction ofν= (−6.39 ± 0.96) × 10−10rad day−2. We also see evidence of surface compositional variation.

Conclusions.The low value of YORP predicted by means of thermo-physical analysis, consistent with the results of the light curve study, might be due to the self-limiting properties of rotational YORP, possibly involving movement of sub-surface and surface material. This may also be consistent with the surface compositional variation that we see. The physical model of Cuyo can be used to investigate cohesive forces as a way to explain why some targets survive rotation rates faster than the fission limit.
82-jährige Patientin mit Aphasie und Apraxie
Authors: Dafotakis Manuel
Published: June 2019

Die notfallmäßige Vorstellung der 82-jährigen Patientin in unserer Notaufnahme erfolgte als Verlegung aus einem anderen Krankenhaus bei zunehmender Verwirrtheit und Sturz aus dem Bett. Laut Angehörigen sei der Zustand der bis dahin fitten Rentnerin in den Tagen vor der Aufnahme kontinuierlich schlechter geworden. Eine Demenz sei im Vorfeld nicht bekannt gewesen.
Intravitreale Injektionen – welche Informationen aus dem Aufklärungsgespräch bleiben Patienten im Gedächtnis?
Authors: Enders Christian , Ryszka Joanna , Lang Gabriele E. , Strametz Reinhard , Lang Gerhard K. , Werner Jens Ulrich
Published: June 2019

Hintergrund Die intravitreale operative Medikamenteneingabe (IVOM) ist eine der häufigsten ophthalmologischen Operationen. Eine hohe Therapieadhärenz ist erforderlich, um einen guten Behandlungserfolg zu erreichen. Da der Wissensstand der Patienten um Krankheit und Therapie mit einer erhöhten Therapieadhärenz assoziiert ist, wurde dieser systematisch erhoben.

Patienten und Methode Die Studie wurde als explorative Befragung konzipiert. Insgesamt wurden im Zeitraum von November bis Dezember 2016 100 konsekutive Patienten der Ambulanz einer Universitätsaugenklinik ein anonymisierter, strukturierter Fragebogen mit mehrheitlich geschlossenen Fragen ausgehändigt. Die Auswertung erfolgte deskriptiv.

Ergebnisse Das mediane Alter betrug 73 Jahre. Über die Hälfte der Patienten hatte bereits 3 oder mehr IVOMs an einem Auge bekommen. Die häufigste Erkrankung war eine altersbezogene Makuladegeneration (52%). 64% der Patienten erhofften sich eine Verbesserung des Sehvermögens. 42% der Patienten konnten das verwendete Präparat nicht benennen. 55% der Patienten fühlten sich ausreichend aufgeklärt. 69% der Patienten konnten nicht einschätzen, wie häufig eine Endophthalmitis nach IVOM auftritt.

Schlussfolgerung Der Wissensstand der Patienten bez. Augenerkrankung, Zielsetzung der Therapie und postoperativen Komplikationen wies trotz vorheriger ausführlicher Aufklärung Lücken auf. Standardisierte Informationsblätter sind von den Patienten gewünscht und können helfen, den Wissensstand sowie die Therapieadhärenz zu verbessern.
Cytotoxic Secondary Metabolites from the Endolichenic Fungus Hypoxylon fuscum
Authors: Basnet Buddha Bahadur , Chen Baosong , Suleimen Yerlan Melsuly , Ma Ke , Guo Shouyu , Bao Li , Huang Ying , Liu Hongwei
Published: June 2019

As part of our search for new cytotoxic and antimicrobial natural products from endolichenic fungi, 19 compounds including 1 new 10-member lactone (2), 1 new polyacetylene glycoside (3), 1 new brasilane-type sesquiterpenoid glycoside (4), and 2 isobenzofuran-1(3H)-one derivatives (5 and 6) were isolated from the solid culture of the endolichenic fungus Hypoxylon fuscum. Their structures were unambiguously elucidated by NMR spectroscopic data, MS, ECD (electronic circular dichroism) calculation, and chemical methods. The cytotoxic effects on K562, SW480, and HEPG2 cell lines and the antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Candida albicans were assessed. Compounds 1, 2, and 5 exhibited moderate cytotoxicity against K562, SW480, and HEPG2 cell lines while compounds 1, 9, and 11 displayed weak antibacterial activity against S. aureus.
Care of the Brain-Dead Organ Donor
Authors: Siah Julian W. R. , Sudhan Nazneen , Wijayatilake Dhuleep S.
Published: June 2019

There remains a worldwide shortage of organs for transplantation. If not properly cared for, the organs of patients who are brainstem dead will deteriorate, making them either unsuitable for transplantation or reducing the success rate of transplants. The Medline database was searched with no time limit in January 2019 for English publications using keywords “brainstem death physiology” and “organ donor care.” Full texts of all publications related to care of deceased donors after brainstem death (DBD) were reviewed. Those that were not relevant were excluded. An online search for publications and guidelines produced by international organizations relating to organ donation and care of the organ donor was also preformed, and the results were reviewed.

Although there is a low level of evidence to support specific management strategies to optimize the care of potential DBD patients, there is reasonable consensus between different international guidelines on protocolized intensive care unit (ICU) management of potential DBD patients and donor resuscitation targets.

Key management concepts include (1) early recognition of brainstem DBD and referral to organ donation services, (2) ICU-led multidisciplinary team (MDT) approach to donor management, (3) shift in ICU teams thinking from management of raised intracranial pressure (ICP) to maintaining organ perfusion and function, (4) early active donor management to normalize donor physiology, and (5) prevention, recognition, and treatment of complications of brainstem death.
Study of tilted orthorhombic twins and leakage current in epitaxial SmFeO3 thin films
Authors: Panchwanee Anjali , Raghavendra Reddy V. , Choudhary R. J. , Phase D. M. , Ganesan V. , Gupta Ajay
Published: June 2019

The effect of oxygen partial pressure (OPP) during deposition on the structural and ferroelectric properties of epitaxial SmFeO3 (SFO) thin films is studied in the present report. The thin films are deposited using the pulsed laser ablation method. Two (00l) oriented substrates, viz., LaAlO3 (LAO) and niobium doped SrTiO3 (Nb:STO), are used for the deposition of films with 35 and 170 nm thicknesses at different OPP values. The prepared films are found to be of single phase and grow in the out-of-plane configuration SFO(hh0)/LAO(00l) using x-ray 2θ−ω and ϕ scans. The epitaxial relationship between the substrate and the film, domain twinning, is confirmed by reciprocal space map measurements. Films of higher thickness exhibit tilted twin structures, more prominently for the films prepared at lower OPP. A significant change in the leakage current is observed as a function of OPP, and the results are explained in terms of the microstructure of the films.
Fault diagnosis method and application based on unsaturated piecewise linear stochastic resonance
Authors: Li Zhixing , Liu Xiandong , Han Songjiu , Wang Jianguo , Ren Xueping
Published: June 2019

Signal detection and processing have become an important way to diagnose mechanical faults. The classical bistable stochastic resonance (CBSR) method for signal detection can become saturated, where the amplitude of the output signal gradually stabilizes at a relatively low level instead of increasing with further increases of the input signal amplitude. This leads to difficulty in extracting the weak signals from strong background noise. We studied a new mechanism based on unsaturated piecewise linear stochastic resonance (PLSR). The piecewise linear potential model has a unique structure, which can independently adjust the barrier height and potential wall inclination, so the piecewise linear potential model has a rich potential structure. The rich potential structure makes the potential model unsaturated, thus ensuring that the output signals increase as the input signals increase. In addition, according to the piecewise linear model, the output signal-to-noise ratio (SNR) of the system is deducted. Analysis of the influence of signal strength, potential parameters, and angular frequency on the SNR shows that the optimal SNR can be obtained by adjusting the potential parameters. We propose a weak signal detection method for bearing fault diagnosis. This method can effectively extract the weak fault signals from rolling bearings in a strong noise background. The simulated and experimental bearing fault signals verify that the proposed PLSR method is superior to the CBSR method.
Four-channel generator of 8-GHz radiation based on gyromagnetic non-linear transmitting lines
Authors: Ulmaskulov M. R. , Shunailov S. A. , Sharypov K. A. , Yalandin M. I. , Shpak V. G. , Rukin S. N. , Pedos M. S.
Published: June 2019

Test results of high-voltage one- and four-channel radio-frequency (RF) generators based on the coaxial gyromagnetic ferrite-filled nonlinear transmission lines (NLTL) with external magnetic bias and RF-modulation frequency of a high-voltage pulse envelope of ∼8 GHz are presented. Electrical strength of oil-isolated NLTLs was tested in a compact version of one-channel generator based on the RADAN driver at a repetition rate of 100 pps. In case of a stationary setup, 5-ns pulse with −500 kV amplitude was split into 4 channels with individual NLTLs. Gyromagnetic line output pulses had fast damped RF-modulation with a maximum modulation depth more than 50% and the peak amplitude of −200 kV. Independent control of a delay time in each channel was realized by the coaxial spiral lines with a central biased ferrite core. The coherent summation possibility of RF fields in the free space radiated by a 4-channel system of conical dielectric antennas was demonstrated.
A benchtop shock physics laboratory: Ultrafast laser driven shock spectroscopy and interferometry methods
Authors: Powell M. S. , Bowlan P. R. , Son S. F. , Bolme C. A. , Brown K. E. , Moore D. S. , McGrane S. D.
Published: June 2019

Common Ti:sapphire chirped pulse amplified laser systems can be readily adapted to be both a generator of adjustable pressure shock waves and a source for multiple probes of the ensuing ultrafast shock dynamics. In this paper, we detail experimental considerations for optimizing the shock generation, interferometric characterization, and spectroscopic probing of shock dynamics with visible and mid-infrared transient absorption. While we have reported results using these techniques elsewhere, here we detail how the spectroscopies are integrated with the shock and interferometry experiment. The interferometric characterization uses information from beams at multiple polarizations and angles of incidence combined with thin film equations and shock dynamics to determine the shock velocity, particle velocity, and shocked refractive index. Visible transient absorption spectroscopy uses a white light supercontinuum in a reflection geometry, synchronized to the shock wave, to time resolve shock-induced changes in visible absorption such as changes to electronic structure or strongly absorbing products and intermediates due to reaction. Mid-infrared transient absorption spectroscopy uses two color filamentation supercontinuum generation combined with a simple thermal imaging microbolometer spectrometer to enable broadband single shot detection of changes in the vibrational spectra. These methods are demonstrated here in the study of shock dynamics at stresses from 5 to 30 GPa in organic materials and from a few GPa to >70 GPa in metals with spatial resolution of a few micrometers and temporal resolution of a few picoseconds. This experiment would be possible to replicate in any ultrafast laser laboratory containing a single bench top commercial chirped pulse amplification laser system.
Negative differential resistance and magnetotransport in Fe3O4/SiO2/Si heterostructures
Authors: Liu Xiang , Mi Wenbo , Zhang Qiang , Zhang Xixiang
Published: June 2019

The electronic transport and magnetotransport properties of Fe3O4/SiO2/Si heterostructures were investigated with a current source. Negative differential resistance is observed in Fe3O4/SiO2/p-Si heterostructures. The measurement circuit with four electrodes that I+ (I−) and V+ (V−) came into contact with the Fe3O4 (Si) layer introduces an in-plane transport into the heterostructures. By decreasing the temperature, the in-plane conductive channel switches from Fe3O4 to p-Si. However, the in-plane current is still carried by Fe3O4 in Fe3O4/SiO2/n-Si heterostructures. The formation of an accumulation layer in p-Si facilitates conductive channel switching (CCS), while the depletion layer in n-Si hampers the CCS. At 150 K, a magnetic-field-independent magnetoresistance (MR) in Fe3O4/SiO2/p-Si heterostructures manifests the conductive channel in the space charge region of p-Si. A positive MR generated from the increased electronic scattering in a trapezoidal space charge region reshaped by the magnetic field has been detected.
Effect of sample temperature on time-resolved laser-induced breakdown spectroscopy
Authors: Guo Kaimin , Chen Anmin , Xu Wanpeng , Zhang Dan , Jin Mingxing
Published: June 2019

Increasing sample temperature is an effective method for improving emission intensity of laser-induced breakdown spectroscopy (LIBS). An increase in the sample temperature requires only simple modification to LIBS system, and does not require sample pretreatment. In addition, the formation and decay of laser-induced plasma (LIP) are a dynamic physical process. Time-resolved spectroscopy can enrich the dynamic information of LIBS and increase data dimension. The further analysis of the time-resolved LIBS data has the potential to understand the physical process. In this study, a beam of nanosecond laser was used to excite brass sample to produce plasma. The time-resolved spectroscopy of the LIP was measured at different sample temperatures. The results indicated that increasing sample temperature improved optical emission intensity in LIBS, and increased the plasma persistence. We also obtained plasma temperature and electron density at different sample temperatures. The time-resolved plasma temperature and electron density in the case with higher sample temperature were higher than those in the case with lower sample temperature. Moreover, the decay of electron density at higher sample temperature was faster than that at lower sample temperature.
RKKY interaction in Mn-doped 4 × 4 Luttinger systems
Authors: Verma Sonu , Kundu Arijit , Ghosh Tarun Kanti
Published: June 2019

We consider Mn-doped bulk zinc-blende semiconductors described by the 4 × 4 Luttinger Hamiltonian. In these semiconductors, the Mn atom acts as an acceptor providing the system a mobile hole and also acts like a magnetic impurity of spin S=5/2. We obtain exact analytical expressions of the hole mediated Ruderman-Kittel-Kasuya-Yoshida (RKKY) exchange interaction between two Mn2+ ions. The RKKY interaction of the Luttinger system consists of collinear Heisenberg-like and Ising-like interactions. The characteristic beating patterns appear in the range functions of the RKKY interaction owing to the presence of multiple Fermi wave-vectors of the underlying j=3/2 states. As an application of the analytical form of the range function, from the finite temperature evaluation of the correlation functions, we calculate the contribution of RKKY interaction to the Curie-Weiss temperatures of a particular dilute magnetic semiconductor ZnMnTe where the 4 × 4 Luttinger Hamiltonian is valid.
A three-dimensional modeling for coalescence of multiple cavitation bubbles near a rigid wall
Authors: Han Rui , Tao Longbin , Zhang A-Man , Li Shuai
Published: June 2019

The Boundary Integral Method (BIM) has been widely and successfully applied to cavitation bubble dynamics; however, the physical complexities involved in the coalescence of multiple bubbles are still challenging for numerical modeling. In this study, an improved three-dimensional (3D) BIM model is developed to simulate the coalescence of multiple cavitation bubbles near a rigid wall, including an extreme situation when cavitation bubbles are in contact with the rigid wall. As the first highlight of the present model, a universal topological treatment for arbitrary coalescence is proposed for 3D cases, combined with a density potential method and an adaptive remesh scheme to maintain a stable and high-accuracy calculation. Modeling for the multiple bubbles attached to the rigid boundary is the second challenging task of the present study. The effects of the rigid wall are modeled using the method of image; thus, the boundary value problem is transformed to the coalescence of real bubbles and their images across the boundary. Additionally, the numerical difficulties associated with the splitting of a toroidal bubble and self-coalescence due to the self-film-thinning process of a coalesced bubble are successfully overcome. The present 3D model is verified through convergence studies and further validated by the purposely conducted experiments. Finally, representative simulations are carried out to elucidate the main features of a coalesced bubble near a rigid boundary and the flow fields are provided to reveal the underlying physical mechanisms.
Effects of drive amplitude on continuous jet break-up
Authors: McIlroy Claire , Harlen Oliver G.
Published: June 2019

We develop a one-dimensional model of jet breakup in continuous inkjet printing to explore the nonlinear behavior caused by finite-amplitude modulations in the driving velocity, where jet stability deviates from classic (linear) “Rayleigh” behavior. At low driving amplitudes and high Weber numbers, the spatial instability produces drops that pinch-off downstream of the connecting filament, leading to the production of small satellite droplets between the main drops. On the other hand, we identify a range of driving amplitudes where pinching becomes “inverted,” occurring upstream of the filament connecting the main drops, rather than downstream. This inverted breakup is preferable in printing, as it increases the likelihood of satellite drops merging with the main drops. We find that this behavior can be controlled by the addition of a second harmonic to the driving signal. This model is in quantitative agreement with a full axisymmetric simulation, which incorporates nozzle geometry.
Deformation characteristics and energy conversion during droplet impact on a water surface
Authors: Ma Huimin , Liu Changgen , Li Xu , Huang Hongbo , Dong Jiaojiao
Published: June 2019

The present work studies experimentally and numerically the impact of water droplets with different Weber numbers (We) on a water surface. Correlations between Weber number and geometric sizes of central jet, secondary droplet, and secondary central jet are analyzed using linear regression. The experimental and numerical results are compared qualitatively and quantitatively and show good agreement. In addition, the energy conversion during the impact process is calculated using a numerical integration method. It is concluded that the ratio of the secondary droplet to the initial droplet diameters is approximately within 1.2–2, and this diameter ratio correlates linearly with the Weber number within the experimental ranges tested. When 360 < We < 713, the secondary central jet is generated. Moreover, the target liquid adsorbs around 70% of the initial total energy. The total energy remains around 64% when the cavity reaches its maximum depth, whereas it remains around 39% when the kinetic energy of the central jet reaches its minimum.
Novel electrospun poly(lactic acid)/poly(butylene carbonate)/graphene oxide nanofiber membranes for antibacterial applications
Authors: Gu Xiaohua , Li Yan , Cao Rui , Liu Siwen , Fu Congzhi , Feng Shuqin , Yang Changlong , Cheng Weidong , Wang Yuhui
Published: June 2019

In this work, Poly(lactic acid) (PLA)/poly(butylene carbonate) (PBC)/graphene oxide (GO) nanofiber membranes with different content GO were successfully prepared by electrospinning. The structural and physical characteristics of the membranes were investigated by scanning electron microscopy (SEM), Differential Scanning Calorimeter (DSC), contact angle test, Fourier Transform Infrared Spectroscopy (FT-IR), agar diffusion method. SEM observations revealed a fine dispersion of GO in the nanofiber matrices. FT-IR spectra result showed that the GO, PBC and PLA mixed well in the PLA/PBC/GO films. The antibacterial properties of nanofiber membranes were also investigated. The results indicated that the antimicrobial activities of PLA/PBC/GO composite nanofibrous films were much higher than that of pure PLA/PBC nanofibrous films. Meanwhile, the antimicrobial activity against S.aureus was also slightly higher than E. coli.
Effect of aggregation on adsorption phenomena
Authors: Litniewski M. , Ciach A.
Published: June 2019

Adsorption at an attractive surface in a system with particles self-assembling into small clusters is studied by molecular dynamics simulation. We assume Lennard-Jones plus repulsive Yukawa tail interactions and focus on small densities. The relative increase in the temperature at the critical cluster concentration near the attractive surface (CCCS) shows a power-law dependence on the strength of the wall-particle attraction. At temperatures below the CCCS, the adsorbed layer consists of undeformed clusters if the wall-particle attraction is not too strong. Above the CCCS or for strong attraction leading to flattening of the adsorbed aggregates, we obtain a monolayer that for strong or very strong attraction consists of flattened clusters or stripes, respectively. The accumulated repulsion from the particles adsorbed at the wall leads to a repulsive barrier that slows down the adsorption process, and the accession time grows rapidly with the strength of the wall-particle attraction. Beyond the adsorbed layer of particles, a depletion region of a thickness comparable with the range of the repulsive tail of interactions occurs, and the density in this region decreases with increasing strength of the wall-particle attraction. At larger separations, the exponentially damped oscillations of density agree with theoretical predictions for self-assembling systems. Structural and thermal properties of the bulk are also determined. In particular, a new structural crossover associated with the maximum of the specific heat and a double-peaked histogram of the cluster size distribution are observed.
A qualitative investigation of barriers, support-seeking and coping among South Sudanese people with chronic hepatitis B in Australia
Authors: Mude William , Fisher Christopher , Richmond Jacqui , Wallace Jack , Le Gautier Roslyn
Published: June 2019

This inquiry examines health-seeking practices and challenges among South Sudanese people from refugee backgrounds with chronic hepatitis B in Australia. Fifteen semi-structured interviews were conducted. Using interpretative thematic analysis, the results revealed four themes, consisting of barriers and facilitators to clinical follow up, treatment and support-seeking practices and coping responses. Time constraints, having divergent views about treatment decisions and perceived inadequate clinical support were also identified as barriers. Being referred to a specialist, being aware of the risk associated with liver cancer and sending reminders about appointments were identified as facilitators to clinical follow up. Treatment-seeking practices involved both biomedical and alternative therapies. Participants mainly drew on their social networks and supports, religious beliefs and individual resilience as coping strategies. The findings are important for improving access to treatment and care and support for people with chronic hepatitis B from the South Sudanese community.
Plastic responses to novel environments are biased towards phenotype dimensions with high additive genetic variation
Authors: Noble Daniel W. A. , Radersma Reinder , Uller Tobias
Published: June 2019

Environmentally induced phenotypes have been proposed to initiate and bias adaptive evolutionary change toward particular directions. The potential for this to happen depends in part on how well plastic responses are aligned with the additive genetic variance and covariance in traits. Using meta-analysis, we demonstrate that plastic responses to novel environments tend to occur along phenotype dimensions that harbor substantial amounts of additive genetic variation. This suggests that selection for or against environmentally induced phenotypes typically will be effective. One interpretation of the alignment between the direction of plasticity and the main axis of additive genetic variation is that developmental systems tend to respond to environmental novelty as they do to genetic mutation. This makes it challenging to distinguish if the direction of evolution is biased by plasticity or genetic “constraint.” Our results therefore highlight a need for new theoretical and empirical approaches to address the role of plasticity in evolution.
CarD contributes to diverse gene expression outcomes throughout the genome of
Mycobacterium tuberculosis
Authors: Zhu Dennis X. , Garner Ashley L. , Galburt Eric A. , Stallings Christina L.
Published: June 2019

The ability to regulate gene expression through transcription initiation underlies the adaptability and survival of all bacteria. Recent work has revealed that the transcription machinery in many bacteria diverges from the paradigm that has been established in
Escherichia coli
.
Mycobacterium tuberculosis
(
Mtb
) encodes the RNA polymerase (RNAP)-binding protein CarD, which is absent in
E. coli
but is required to form stable RNAP-promoter open complexes (RP
o
) and is essential for viability in
Mtb
. The stabilization of RP
o
by CarD has been proposed to result in activation of gene expression; however, CarD has only been examined on limited promoters that do not represent the typical promoter structure in
Mtb
. In this study, we investigate the outcome of CarD activity on gene expression from
Mtb
promoters genome-wide by performing RNA sequencing on a panel of mutants that differentially affect CarD’s ability to stabilize RP
o
. In all CarD mutants, the majority of
Mtb
protein encoding transcripts were differentially expressed, demonstrating that CarD had a global effect on gene expression. Contrary to the expected role of CarD as a transcriptional activator, mutation of CarD led to both up- and down-regulation of gene expression, suggesting that CarD can also act as a transcriptional repressor. Furthermore, we present evidence that stabilization of RP
o
by CarD could lead to transcriptional repression by inhibiting promoter escape, and the outcome of CarD activity is dependent on the intrinsic kinetic properties of a given promoter region. Collectively, our data support CarD’s genome-wide role of regulating diverse transcription outcomes.
Advancing the understanding of placebo effects in psychological outcomes of exercise: Lessons learned and future directions
Authors: Lindheimer Jacob B. , Szabo Attila , Raglin John S. , Beedie Chris
Published: June 2019

Despite the apparent strength of scientific evidence suggesting that psychological benefits result from both acute and chronic exercise, concerns remain regarding the extent to which these benefits are explained by placebo effects. Addressing these concerns is methodologically and at times conceptually challenging. However, developments in the conceptualisation and study of placebo effects from the fields of psychology, neuroscience, pharmacology, and human performance offer guidance for advancing the understanding of placebo effects in psychological responses to exercise. In clinical trials, expectations can be measured and experimentally manipulated to better understand the influence of placebo effects on treatment responses. Further, compelling evidence has shown that the contribution of placebo effects and their underlying neurobiological mechanisms to treatment effects can be measured without administering a traditional placebo (e.g. inert substance) by leveraging psychological factors such as expectations and conditioning. Hence, the purpose of this focused review is to integrate lessons such as these with the current body of literature on placebo effects in psychological responses to exercise and provide recommendations for future research directions.
Cooperative phases and phase transitions of Bose condensed light in dye filled cavities
Authors: Fleurov Victor , Kuklov Anatoly
Published: June 2019

Recent realization of Bose–Einstein condensation of light in 2D provides a new platform for studying novel phases and phase transitions. The combination of low effective mass of the confined light and the presence of the dye molecules with randomly oriented directions of the dipolar transition engages a competition between disorder and the tendency to forming algebraic off-diagonal order. The phase diagram of possible phases is constructed at the mean field level. One of the phases is the condensate of photon pairs induced solely by the orientational disorder. Such a geometrical mechanism of pairing has no analogy in other systems.
Analytic solution for a joint Bohm sheath and pre-sheath potential profile
Authors: Martin P , Maass F , Calderón F A , Lastra F
Published: June 2019

An analytic solution is presented in this paper for the electric potential near a wall in a confined plasma. This is well fitted for both the sheath and pre-sheath regions. In the sheath region, the potential is well adapted to the differential equation proposed by Bohm. In the pre-sheath region, the potential is also well suited, decaying to zero electric field in the plasma, which is a physical condition. The potential is also valid for any value of the parameter K measuring the dimensionless Bohm velocity.
Spectral purity transfer with 5 × 10−17 instability at 1 s using a multibranch Er:fiber frequency comb
Authors: Barbieri Piero , Clivati Cecilia , Pizzocaro Marco , Levi Filippo , Calonico Davide
Published: June 2019

In this work we describe the spectral purity transfer between a 1156 nm ultrastable laser and a 1542 nm diode laser by means of an Er:fiber multibranch comb. By using both the master laser light at 1156 nm and its second-harmonic at 578 nm, together with the 1542 nm slave laser, we investigate the residual noise between the main comb output, the octave-spanning output, and a wavelength conversion module including non-linear fibers, second-harmonic generation crystal and amplifiers. With an ultimate stability of the system at the level of

at 1 s and accuracy of

, this configuration can sustain spectral transfer at the level required by the contemporary optical clocks with a simple and robust setup.
Hand Gesture Recognition with Skin Detection and Deep Learning Method
Authors: Huang Hanwen , Chong Yanwen , Nie Congchong , Pan Shaoming
Published: June 2019

Gesture recognition, although has been exploring for many years, is still a challenging problem. Complex background, camera angles and illumination conditions make the problem more difficult. Thus, this paper presents a fast and robust method for hand gesture recognition based on RGB video. First we detect the skin based on their color. Then we extract the contour and segment the hand region. Finally we recognize the gesture. The results of experiment demonstrate that the proposed method are efficient to recognize gesture with a higher accuracy than the state of the art.
Video Analysis Technology and Its Application in Badminton Sports Training
Authors: Yunwei LI , Shiwei Jiang
Published: June 2019

Based on the continuous development of computer vision and graphics technology, pattern recognition and image processing technology, intelligent video analysis technology combines these related technologies to establish a mapping relationship between image description and surveillance image. Intelligent video analysis technology has a wide range of applications, such as in military and economic fields. In the process of badminton training, when the trainer explains the action essentials for the athletes, the video replay and analysis management methods are less difficult, lack of science and intuition and it is difficult to meet the trainer’s demand for sports performance evaluation. The analysis and recognition process of badminton video are studied. Based on particle filter prediction, adaptive threshold algorithm is used to achieve adaptive separation of moving targets. The particle filter technology is used to track the trajectory of the athletes and the motion model is constructed. Based on this, the position of the important joint points in the subsequent motion video frames is predicted, so as to track the subsequent motion video frames. When the motion recognition in the badminton training video is used, the conditional random field method is mainly used, which makes the motion recognition rate higher and the false separation rate lower.
Wind and Storage Cooperative Scheduling Strategy Based on Deep Reinforcement Learning Algorithm
Authors: Qin Jingtao , Han Xueshan , Liu Guojing , Wang Shang , Li Wenbo , Jiang Zhe
Published: June 2019

Wind energy has become one of the most promising new energy sources in the context of the global energy interconnection. However, the inherent uncertainty of wind power and the volatility of its output make it difficult to join the internet for scheduling. The uncertainty of the output must be reduced or even eliminated by certain methods. In this paper, wind power and energy storage are coordinated to eliminate the uncertainty of wind power output, and to reduce the burden on the grid while ensuring the long-term operation of wind farms. This paper first introduces Q-learning in reinforcement learning as a controller. Through a large number of historical wind power data training, the controller has good decision-making ability, so as to reduce the punishment caused by wind power uncertainty; then the Q-learning is improved aiming at the maximum average income of the stage. Finally, the Q-value network is established with conventional Q-learning and improved Q-learning. The DQN algorithm in the deep reinforcement learning algorithm is introduced for deep training and decision-making and the three algorithms are verified. The result proves that the deep reinforcement learning algorithm can achieve better control effect than Q-learning.
Legitimacy of Personal Data Mining and Related Regulatory Approaches: China’s Choices
Authors: Cui Shujie
Published: June 2019

Personal data mining is a crucial but controversial topic in the big data era. It is widely accepted in the technical filed as a big data technology. While more and more people begin to question its legitimacy for it causes many social and legal problems. This paper tries to demonstrate the legitimacy of personal data mining from the following reasons: a) personal data has certain public goods attribute and sharing characteristic, which is the internal premise of personal data mining; b) data appreciation theory is the theoretical basis of personal data mining; c) the principle of interests balance is the logical requirement of personal data mining; d) big data sharing economy provides practical soil for personal data mining. Based on the legitimacy analysis and China’s data development practices, personal data mining should be encouraged. Meanwhile, it is particularly important to regulate the approaches of personal data mining in four aspects: a) establishing the purpose of combining personal data mining and protection; b) balancing the interests of all parties in the process of personal data mining; c) improving data classification legislation; d) innovating technical means to achieve privacy protection.
The positive integral points on the elliptic curve y2 = (x + 4)(x2 − 4x + 5)
Authors: Xian-cun DU , Zhao Jianhong , Huizhang Yang
Published: June 2019

In this paper, we studied the elliptic curve y
2 = (x – a)(x
2 + ax + r), a, r ∈ Z
+ in the case of a = 6,r = 7 which has no relevant conclusions up to now. And we obtained the conclusion of the integer points on Elliptic y
2 = (x – 6)(x
2 + 6x + 7), elliptic curve in title has only one integer point (x, y) = (6,0) were proved with the help of the elementary methods such as congruence and Legendre symbol.
A Review of the Research on the Prediction Model of Extreme Learning Machine
Authors: Yibo Li , Fang Liu , Qi Cao
Published: June 2019

With the wide application of prediction, the research of prediction algorithm and theory has made a great progress. In recent years, extreme learning machines have been used in the field of prediction, such as stock price prediction. The prediction algorithms of ELM are reviewed in this paper, which includes the single extreme learning machine prediction algorithm and the combined prediction algorithm. At the same time, the existing problems and research directions are pointed out.
Fabrication of spiral fibre on PET substrate by electrospinning direct-writing for flexible electronics
Authors: Pan Yanqiao
Published: June 2019

Spiral fibre has strong flexibility and high porosity, which can be widely used in fabrication of stretchable microelectrode for flexible electronics when functional materials are mixed in fibre. It is attractive and challenging to generate spiral fibre on plastic substrate in a controllable manner. In this paper, polyethylene oxide spiral fibres are successfully fabricated on PET substrate by electrospinning direct-writing. The whole fabrication process of one spiral fibre is observed by a high-speed camera at 10000 fps in order to reveal the internal mechanism. Influence of repulsive forces by remaining electric charges on substrate is the main cause for the unique spiral pattern. This can provide a reference for manufacturing of functional microelectrode in future.
Research and Implement of Cache Fault Tolerance Technique
Authors: Wei Jianlei
Published: June 2019

For the space application, cache rams are easy to be affected by single event upset (SEU). To protect against SEU error, it is necessary to design fault tolerance cache. Multiple bit-flips faults are increasing as integrated circuits continue to scale into the deep sub-micron regime, the error detection ability need to be improved, so an interleaving grouping parity error detection code scheme is proposed in this paper, each 32-bit data and each 19-bit tag adding 4 valid bits adopt 4 parity bits respectively, the adjacent 4 bits data are assigned to different groups, so all less than 8 bits burst faults can be detected. The hit structure and updating structure of the cache memory are redesigned. No timing penalty occurs since parity checking is performed in parallel with tag comparison. The experimental results show that, by using the proposed technique, there is a small performance loss, but the advantage is the higher reliability valuable for safety system. The failure rate of the cache memory is lower by 6 orders of magnitude.
Design of the Photonic Crystal Slot Fractal Array Ultra Wideband Antenna
Authors: Lin Bin , Pan Yilang , Li Zhenchang , Zheng Ping , Wei Xinyu , Hong Zhijie
Published: June 2019

According to the performance requirements of the multi band compatible antennas for the mobile communication system, the radio frequency identification system, the ultra wideband system and the mobile digital TV system, the present paper originally combined photonic crystal structure, embedded slot fractal, rectangular array antenna, relative dielectric constant gradual thin film, potassium tantalum niobate thin film, Fe-based nanocrystalline alloy coating and graphene conductive ink, and designed a photonic crystal slot fractal array ultra wideband antenna. The result of test indicates that this antenna has strong anti-EMI capability, large performance redundancy and ultra wideband operation capability. This antenna completely covered all working frequency bands of the second generation to the fifth generation mobile communication, the frequency bands of the radio frequency identification system, the frequency band of the ultra wideband system, and the frequency band of the mobile digital TV system. This antenna has small size, high radiation intensity, stable and reliable operation performance; it is a microwave band multi network integration antenna with excellent performance.
Research on Spacecraft Abnormal State Detection Method Based on Telemetry Data
Authors: Luo Rongzheng , Tan Zhiyun , Gao He , Liang Ruidong , Feng Shuo
Published: June 2019

A method of spacecraft abnormal state detection based on telemetry data is proposed. The abnormal state of spacecraft is detected by telemetry data preprocessing, correlation calculation, extremum point extraction and abnormal state extraction. This method makes full use of the historical telemetry parameter samples, combines the characteristics of the spacecraft telemetry parameter data and the law of data variation, compares the correlation between the telemetry data over a period of time and its historical sample data, and compares the extreme point errors, so as to realize the spacecraft abnormal state detection with only a small amount of historical data and without design knowledge. It overcomes the dependence of existing abnormal state detection methods on expert experience knowledge and the problem that the existing detection methods cannot solve the abnormal changes of telemetry parameters which do not exceed the normal range. It provides an effective and intuitive method and tool for spacecraft managers to analyze the changes of spacecraft state.
Public-Key applications in E-commerce
Authors: Wang Zhaoqing , Zhao Yusheng , Zhong Guorong
Published: June 2019

In this paper, we describe the application of data encryption technology in E-commerce, and introduce the public key encryption and public key encryption system in detail. Then, we propose a composite encryption model that nests the DES algorithm in the RSA algorithm. Finally, we analyzed two widely used Internet protocols, SET and SLL, which can improve the security of payment and customer trust, and then describe the development of e-commerce by ensuring the security and accuracy of the transaction process.
Study on UCAV Robust Maneuvering Decision in Automatic Air Combat Based on Target Accessible Domain
Authors: Han Tong , Wang Xiaofei , Liang Yajun , Ku Shuo
Published: June 2019

The paper presents a deep study on the robust maneuvering decision of unmanned combat aerial vehicle (UCAV) in air combat. First, a method to descript the target accessible domain by angles is designed. Then the state prediction model of the target with variable weight is built based on the change of target tactical intention. Second, robust membership functions that reflect the air combat situation are denoted to building up the decision method, robust multi-objective optimization (RMO). Finally, grey wolf optimizer (GWO) is adopted to complete the optimization. The simulation result shows that, the model of target state prediction based on accessible domain can reflect the tactical intention and the state prediction can obtain better situation advantage than that without prediction. Moreover, the RMO can get the promising result and the GWO can satisfy the need of maneuvering decision.
Remining Useful Life Prediction of Equipment Driven by Multi-Sensor Data
Authors: Huijie Zeng , Lin Deng , Jiansheng Guo , Jian Wang , Tengjiao Wang , Taoyong Gu
Published: June 2019

This paper presents a method for predicting the remining useful life (RUL) of equipment by using multi-sensor monitoring data of equipment. Firstly, the performance degradation of equipment is evaluated based on the maximum information coefficient. Then the performance degradation model is built by using Wiener process with non-linear drift. The maximum likelihood is used to estimate the parameters of the model, and the probability density distribution of RUL considering random failure threshold is deduced. Finally, the parameters of the model are updated by improved particle filter, and the RUL of the remaining equipment is predicted.
Research on the Extraction Method of Explicit Attribute-View Pairs in Product Review
Authors: Jia Yafang , Lin Shaofu
Published: June 2019

The fine-grained affective analysis of product reviews is a fine-grained mining of the content of reviews, which has important research significance. The explicit attribute-viewpoint extraction is one of its key research issues. Due to the complex structure and colloquial features of online product reviews, traditional models are not ideal for the extraction of explicit attribute-views pairs. To solve this problem, this paper proposes an extraction method based on deep learning and integrating positional relationship information. By using the Bi-directional Long Short-Term Memory Network to overcome the problem of long distance dependence, the author makes full use of the context, combines the attention mechanism to reduce the noise weight of sentence-level informal text, and integrates the feature of position relation to enrich the feature information. The experimental results show that compared with other models, the network model proposed in this paper has improved the call rate and F1 value.
Research on risk control of social endowment insurance fund operation in China
Authors: Yang Rong
Published: June 2019

Social pension is an important and sensitive topic. The reason for this is that there is a huge gap in China’s social endowment insurance. In recent years, the topic and discussion about the pension fund entering the market have never been interrupted. Therefore, it is of great significance to study the risk and risk control of social endowment insurance under such a background. Based on this research background, this paper introduces the current situation and existing problems of China’s endowment insurance, and puts forward some risk control measures to solve these problems, hoping to play a role in relevant research and decision-making.
Effect of different intensity aerobic exercise on sleep quality in patients with type 2 diabetes
Authors: Yang Chunxia , Zhong Xiaoling , Liang Huazhen
Published: June 2019

Diabetes is a chronic disease, especially in type 2 diabetes, which is more common in China. According to the report of the 18th International Diabetes Federation (IDF) meeting, there were about 150 million diabetic patients in the world in 2003, of which type 2 diabetes accounted for 90%-95%, and the global incidence rate is on the rise. In this paper, based on the sense of movement and therapy, the sleep quality of patients with type 2 diabetes was analyzed. Based on the pathological study of the disease, some matters needing attention were put forward, with a view to enlightenment.