bluuebunny/crossref_metadata_2025 huggingface dataset:
Curcumin in Wound Healing—A Bibliometric Analysis
Authors: Farhat Faiza , Sohail Shahab Saquib , Siddiqui Farheen , Irshad Reyazur Rashid , Madsen Dag Øivind
Published: January 2023

Background: Curcumin has been widely used to treat a variety of diseases and disorders since ancient times, most notably for the purpose of healing wounds. Despite the large number of available reviews on this topic, a bibliometric tool-based meta-analysis is missing in the literature. Scope and approach: To evaluate the influence and significance of the countries, journals, organizations and authors that have contributed the most to this topic, the popular bibliometric markers, including article count, citation count, and Hirsch index (H-index), are taken into account. Their collaborative networks and keyword co-occurrence along with the trend analysis are also sketched out using the VOSviewer software. To the best of our knowledge, this is the first bibliometric review on the topic and hence it is envisaged that it will attract researchers to explore future research dimensions in the related field. Key findings and conclusions: India provided the most articles, making up more than 27.49 percent of the entire corpus. The International Journal of Biological Macromolecules published the most articles (44), and it also received the most citations (2012). The Journal of Ethnopharmacology (28 articles) and Current Pharmaceutical Design (20 articles) were the next most prolific journals with 1231 and 812 citations, respectively. The results indicate a significant increase in both research and publications on the wound-healing properties of curcumin. Recent studies have concentrated on creating novel medicine-delivery systems that use nano-curcumin to boost the effect of the curcumin molecule in therapeutic targeting. It has also been observed that genetic engineering and biotechnology have recently been employed to address the commercial implications of curcumin.
Large-Scale Model Test on Water Pressure Resistance of Lining Structure of Water-Rich Tunnel
Authors: Huang Mingli , Huang Meng , Yang Ze
Published: January 2023

In order to solve the problem of testing the water pressure resistance of lining structures of water-rich tunnels and the difficulty of implementing the existing model tests, a large-scale model test method was proposed relying on the New Yuanliangshan Tunnel threatened by high pressure and rich water. This method creatively transformed the external water pressure of the lining structure into internal water pressure, and the conversion coefficient of water resistance of lining under different sizes and loading modes was obtained by numerical calculation. Results showed that the ultimate water pressure resistance of the lining structure under an external uniformly distributed water pressure and local water pressure was 1.44 and 0.67 times of that obtained from the large-scale model tests, respectively. By conducting the large-scale model tests and combining with the conversion coefficient, the water pressure resistance of the actual tunnel lining could be obtained. Research indicated that water pressure resistance of K2.0 (bearing water pressure of 2.0 MPa) type lining at the transition section of karst caves and K3.0 (bearing water pressure of 3.0 MPa) type lining at the section of karst caves of the New Yuanliangshan Tunnel was 3.33 MPa and not less than 4.36 MPa, respectively, and the high reliability of the large-scale model tests was verified by numerical calculation, implying that the model test method could be extended to similar tunnel projects.
ACTAS: A New Framework for Mechanical and Frictional Characterization in Axisymmetric Compression Test
Authors: Solhjoo Soheil
Published: January 2023

There are two common methods to interpret the results of an Axisymmetric Compression Test (ACT): the Cylindrical Profile Model (CPM) and the Avitzur model; however, both of the two and all other models available in the literature ignore the unavoidable foldover phenomenon, which breaks the models to provide reliable friction-free flow stress curves. Here, a novel numerical framework (called ACTAS) is presented that incorporates the foldover. ACTAS can be used to both simulate and analyze ACT. Ten finite element models are used to benchmark ACTAS. The results show the reliability of the proposed method in estimating the average and pointwise stress-strain curves and friction factors. Moreover, a new solution is provided by coupling the CPM and the Avitzur model (called A-CPM), to obtain reliable average flow curves even after the onset of foldover.
Microstructure Evolution, Constitutive Modelling, and Superplastic Forming of Experimental 6XXX-Type Alloys Processed with Different Thermomechanical Treatments
Authors: Mochugovskiy Andrey G. , Mosleh Ahmed O. , Kotov Anton D. , Khokhlov Andrey V. , Kaplanskaya Ludmila Yu. , Mikhaylovskaya Anastasia V.
Published: January 2023

This study focused on the microstructural analysis, superplasticity, modeling of superplastic deformation behavior, and superplastic forming tests of the Al-Mg-Si-Cu-based alloy modified with Fe, Ni, Sc, and Zr. The effect of the thermomechanical treatment with various proportions of hot/cold rolling degrees on the secondary particle distribution and deformation behavior was studied. The increase in hot rolling degree increased the homogeneity of the particle distribution in the aluminum-based solid solution that improved superplastic properties, providing an elongation of ~470–500% at increased strain rates of (0.5–1) × 10−2 s−1. A constitutive model based on Arrhenius and Beckofen equations was used to describe and predict the superplastic flow behavior of the alloy studied. Model complex-shaped parts were processed by superplastic forming at two strain rates. The proposed strain rate of 1 × 10−2 s−1 provided a low thickness variation and a high quality of the experimental parts. The residual cavitation after superplastic forming was also large at the low strain rate of 2 × 10−3 s−1 and significantly smaller at 1 × 10−2 s−1. Coarse Al9FeNi particles did not stimulate the cavitation process and were effective to provide the superplasticity of alloys studied at high strain rates, whereas cavities were predominately observed near coarse Mg2Si particles, which act as nucleation places for cavities during superplastic deformation and forming.
Durability Performance and Corrosion Mechanism of New Basalt Fiber Concrete under Organic Water Environment
Authors: Wei Jun , Wang Zhenshan , Sun Weidong , Yang Runan
Published: January 2023

Under corrosive environments, concrete material properties can deteriorate significantly, which can seriously affect structural safety. Therefore, it has important engineering applications to improve the durability performance at a lower economic cost. This paper proposes a new, highly durable concrete using inexpensive construction materials such as basalt fiber, sodium methyl silicate, and inorganic aluminum salt waterproofing agent. With the massive application of sewage treatment projects, the problem of concrete durability degradation is becoming more and more serious. In this paper, five types of concrete are developed for the sewage environment, and the apparent morphology and fine structure of the specimens after corrosion in sewage were analyzed. The density, water absorption, and compressive strength were measured to investigate the deterioration pattern of concrete properties. It was found that ordinary concrete was subject to significant corrosion, generating large deposits of algae on the surface and accompanied by sanding. The new concrete showed superior corrosion resistance compared to conventional concrete. Among other factors, the inorganic aluminum salt waterproofing agent effect was the most prominent. The study found that the strength of ordinary concrete decreased by about 15% in the test environment, while the new concrete had a slight increase. Comprehensive evaluation showed that the combination of basalt fiber and inorganic aluminum salt waterproofing agent had the best effect. Its use is recommended.
Impact Resistance of a Fiber Metal Laminate Skin Bio-Inspired Composite Sandwich Panel with a Rubber and Foam Dual Core
Authors: Zhang Wenping , Li Ruonan , Yang Quanzhan , Fu Ying , Kong Xiangqing
Published: January 2023

This paper reports the development of a novel bio-inspired composite sandwich panel (BCSP) with fiber metal laminate (FML) face sheets and a dual core to improve the low-velocity impact behavior based on the woodpecker’s head layout as a design template. The dynamic response of BCSP under impact load is simulated and analyzed by ABAQUS/Explicit software and compared with that of the composite sandwich panel (CSP) with a single foam core. The impact behavior of BCSP affected by these parameters, i.e., a different face sheet thickness, rubber core thickness and foam core height, was also reported. The results show that BCSP has superior impact resistance compared to CSP, with a lower damage area and smaller deformation, while carrying a higher impact load. Concurrently, BCSP is not highly restricted to any particular region when dealing with stress distributions. Compared to CSP, the bottom skin maximum stress value of BCSP is significantly reduced by 2.4–6.3 times at all considered impact energy levels. It is also found that the impact efficiency index of BCSP is 4.86 times higher than that of CSP under the same impact energy, indicating that the former can resist the impact load more effectively than the latter in terms of overall performance. Furthermore, the impact resistance of the BCSP improved with the increase in face sheet thickness and rubber core thickness. Additionally, the height of the foam core has a notable effect on the energy absorption, while it does not play a significant role in impact load. From an economic viewpoint, the height of the foam core retrofitted with 20 mm is reasonable. The results acquired from the current investigation can provide certain theoretical reference to the use of the bio-inspired composite sandwich panel in the engineering protection field.
Towards Room Temperature Phase Transition of W-Doped VO2 Thin Films Deposited by Pulsed Laser Deposition: Thermochromic, Surface, and Structural Analysis
Authors: Bleu Yannick , Bourquard Florent , Barnier Vincent , Loir Anne-Sophie , Garrelie Florence , Donnet Christophe
Published: January 2023

Vanadium dioxide (VO2) with an insulator-to-metal (IMT) transition (∼68 °C) is considered a very attractive thermochromic material for smart window applications. Indeed, tailoring and understanding the thermochromic and surface properties at lower temperatures can enable room-temperature applications. The effect of W doping on the thermochromic, surface, and nanostructure properties of VO2 thin film was investigated in the present proof. W-doped VO2 thin films with different W contents were deposited by pulsed laser deposition (PLD) using V/W (+O2) and V2O5/W multilayers. Rapid thermal annealing at 400–450 °C under oxygen flow was performed to crystallize the as-deposited films. The thermochromic, surface chemistry, structural, and morphological properties of the thin films obtained were investigated. The results showed that the V5+ was more surface sensitive and W distribution was homogeneous in all samples. Moreover, the V2O5 acted as a W diffusion barrier during the annealing stage, whereas the V+O2 environment favored W surface diffusion. The phase transition temperature gradually decreased with increasing W content with a high efficiency of −26 °C per at. % W. For the highest doping concentration of 1.7 at. %, VO2 showed room-temperature transition (26 °C) with high luminous transmittance (62%), indicating great potential for optical applications.
Novel Load Systems for In Vitro Testing of Biomaterials and Medical Devices
Authors: Bignardi Cristina , Terzini Mara
Published: January 2023

In the mechanical characterization of materials or devices, the real load conditions to which they will be subjected in their operational environment must often be simulated by starting from the availability of universal testing machines [...]
Synergistic Catalytic Effect of Ag and MgO Nanoparticles Supported on Defective BN Surface in CO Oxidation Reaction
Authors: Konopatsky Anton S. , Leybo Denis V. , Kalinina Vladislava V. , Zilberberg Igor L. , Antipina Liubov Yu. , Sorokin Pavel B. , Shtansky Dmitry V.
Published: January 2023

Micron-sized supports of catalytically active nanoparticles (NPs) can become a good alternative to nanocarriers if their structure is properly tuned. Here, we show that a combination of simple and easily scalable methods, such as defect engineering and polyol synthesis, makes it possible to obtain Ag and MgO nanoparticles supported on defective hexagonal BN (h-BN) support with high catalytic activity in the CO oxidation reaction. High-temperature annealing in air of Mg-containing (<0.2 at.%) h-BN micropellets led to surface oxidation, the formation of hexagonal-shaped surface defects, and defect-related MgO NPs. The enhanced catalytic activity of Ag/MgO/h-BN materials is attributed to the synergistic effect of h-BN surface defects, ultrafine Ag and MgO NPs anchored at the defect edges, and MgO/Ag heterostructures. In addition, theoretical simulations show a shift in the electron density from metallic Ag towards MgO and the associated decrease in the negative charge of oxygen adsorbed on the Ag surface, which positively affects the catalytic activity of the Ag/MgO/h-BN material.
Top-down Determination of Fluctuations in Topographic Measurements
Authors: Lemesle Julie , Moreau Clement , Deltombe Raphael , Blateyron François , Martin Joseph , Bigerelle Maxence , Brown Christopher A.
Published: January 2023

A top-down method is presented and studied for quantifying topographic map height (z) fluctuations directly from measurements on surfaces of interest. Contrary to bottom-up methods used in dimensional metrology, this method does not require knowledge of transfer functions and fluctuations of an instrument. Fluctuations are considered here to be indicative of some kinds of uncertainties. Multiple (n), successive topographic measurements (z = z(x,y)) are made at one location without moving the measurand relative to the measurement instrument. The measured heights (z) at each position (x,y) are analyzed statistically. Fluctuation maps are generated from the calculated variances. Three surfaces were measured with two interferometric measuring microscopes (Bruker ContourGT™ and Zygo NewView™ 7300). These surfaces included an anisotropic, turned surface; an isotropic, sandblasted surface; and an abraded, heterogeneous, multilayer surface having different, complex, multiscale morphologies. In demonstrating the method, it was found that few non-measured points persisted for all 100 measurements at any location. The distributions of uncertainties are similar to those of certain features on topographic maps at the same locations, suggesting that topographic features can augment measurement fluctuations. This was especially observed on the abraded ophthalmic lens; a scratch divides the topographic map into two zones with different uncertainty values. The distributions of fluctuations can be non-Gaussian. Additionally, they can vary between regions within some measurements.
Pd–Co-Based Electrodes for Hydrogen Production by Water Splitting in Acidic Media
Authors: Patella Bernardo , Zanca Claudio , Ganci Fabrizio , Carbone Sonia , Bonafede Francesco , Aiello Giuseppe , Miceli Rosario , Pellitteri Filippo , Mandin Philippe , Inguanta Rosalinda
Published: January 2023

To realize the benefits of a hydrogen economy, hydrogen must be produced cleanly, efficiently and affordably from renewable resources and, preferentially, close to the end-users. The goal is a sustainable cycle of hydrogen production and use: in the first stage of the cycle, hydrogen is produced from renewable resources and then used to feed a fuel cell. This cycle produces no pollution and no greenhouse gases. In this context, the development of electrolyzers producing high-purity hydrogen with a high efficiency and low cost is of great importance. Electrode materials play a fundamental role in influencing electrolyzer performances; consequently, in recent years considerable efforts have been made to obtain highly efficient and inexpensive catalyst materials. To reach both goals, we have developed electrodes based on Pd–Co alloys to be potentially used in the PEMEL electrolyzer. In fact, the Pd–Co alloy is a valid alternative to Pt for hydrogen evolution. The alloys were electrodeposited using two different types of support: carbon paper, to fabricate a porous structure, and anodic alumina membrane, to obtain regular arrays of nanowires. The goal was to obtain electrodes with very large active surface areas and a small amount of material. The research demonstrates that the electrochemical method is an ideal technique to obtain materials with good performances for the hydrogen evolution reaction. The Pd–Co alloy composition can be controlled by adjusting electrodeposition parameters (bath composition, current density and deposition time). The main results concerning the fabrication process and the characterization are presented and the performance in acid conditions is discussed.
Frontiers in Restorative Dentistry Biomaterials and Endodontic Instruments
Authors: Poggio Claudio , Gallo Simone
Published: January 2023

Restorative dentistry deals with the prevention, diagnosis, and treatment of pathological conditions affecting the teeth, to restore their function and aesthetics [...]
Effect of Wood Dust Fibre Treatments Reinforcement on the Properties of Recycled Polypropylene Composite (r-WoPPC) Filament for Fused Deposition Modelling (FDM)
Authors: Nafis Z. A. S. , Nuzaimah M. , Kudus S. I. Abdul , Yusuf Y. , Ilyas R. A. , Knight V. F. , Norrrahim M. N. F.
Published: January 2023

The efficacy of wood dust fibre treatment on the property of wood dust reinforced recycled polypropylene composite (r-WoPPC) filament was investigated. The wood dust fibre was treated using alkali, silane, and NaOH-silane. The treated wood fibre was incorporated with r-PP using a twin-screw extruder to produce filament. The silane treatment on wood dust fibre enhances interfacial bonding between wood fibre and recycled PP; hence, a filament has the highest wire pull strength, which is 35.2% higher compared to untreated and alkaline-treated wood dust filament. It is because silanol in silane forms a siloxane bond that acts as a coupling agent that improves interfacial bonding between wood dust fibre and recycled PP. The SEM micrograph of the fracture structure reveals that treated silane has strong interfacial bonding between wood dust fibre and recycled PP, having minimal void, gap, and good fibre adhesion. The water absorption test results indicate that filament with treated wood dust absorbs less water than filament with untreated wood because the treatment minimizes the gap between wood fibres and recycled PP. The FTIR analysis identified the presence of silane on the wood dust surface for silane-treated wood dust. The DSC studies suggest that the temperature range 167–170 °C be used in the extrusion machine to produce r-WoPPC filament. As a result, r-WoPPc filaments containing silane-treated wood dust have better mechanical properties and have a greater potential for usage in FDM applications.
Influence of Basalt/Polypropylene Fiber on Permeability and Uniaxial Compressive Properties of Waste Tire Rubberized Concrete
Authors: Su Dan-yang , Pang Jian-yong , Han Chen-yue , Huang Jian-yu , Hu Xiu-yue , Shi Wei
Published: January 2023

The rubber particles obtained from the grinding of waste tires can replace a portion of the fine aggregates in concrete, thus effectively reducing the level of environmental damage and saving resources. However, when concrete is mixed with rubber, it greatly reduces its strength. In this study, by introducing basalt fiber (BF) and polypropylene fiber (PF) as modified materials in rubberized concrete, the influence of the fiber type/volume ratio on the slump, water absorption, static uniaxial compression, and permeability of the rubberized concrete was tested. The axial compression stress–strain relationship was analyzed, the effect of the fiber type/volume ratio on the energy dissipation of the rubberized concrete during uniaxial compression was expounded, and a stress–strain constitutive model under uniaxial compression was established. The test results showed that the fiber reduces the fluidity and water absorption of the rubberized concrete. Compared with the polypropylene fiber, the basalt fiber increased the strength of the rubberized concrete, while the polypropylene fiber mainly inhibited the expansion and penetration of the macroscopic crack of the rubberized concrete. The mixing of the basalt fiber and polypropylene fiber significantly decreased the release rate of the elastic strain energy of the rubberized concrete, increased the dissipation energy, and thus improved its ductility and toughness. During a loading process under confining pressure, the permeability of the tested specimen decayed exponentially, and the fiber greatly enhanced the anti-permeability of the rubber concrete.
Investigation of Unsteady Pressure Pulsations of Reactor Coolant Pump Passage under Flow Coast-down
Authors: Ye Daoxing , Wu Jinchen , Liu Anlin , Chen Junlin , Zhai Fengli , Lai Xide
Published: January 2023

In order to obtain the pressure pulsations of a reactor coolant pump during flow coast-down conditions, the time-domain characteristics of the flow passage under different times of flow coast-down were calculated by numerical calculation. Because the unsteady pressure pulsation signals in the RCP under flow coast-down are non-stationary and some phenomena may only occur in a short time, this paper analyzed them with the wavelet transform. The results show that the pressure fluctuation varies dramatically with the flow coast-down process and the variation rate of the pressure fluctuation coefficient can reach more than 60%. With the development of flow coast-down, there is a strong correlation between the pressure pulsation and number of impeller blades. The main frequency of the pressure pulsation gradually changes from high-frequency pulsation to low-frequency pulsation, and the regularity of the pressure pulsation is quickly destroyed, while the change in pressure pulsation regularity of the guide vane passage is more gentle than that of the impeller and pressurized water chamber. The change in wavelet intensity at the impeller outlet, guide vane inlet, and left side of the pressurized water chamber is more intense than at other areas.
Optimal Design of High-Speed Electric Machines for Electric Vehicles: A Case Study of 100 kW V-Shaped Interior PMSM
Authors: El Hajji Taha , Hlioui Sami , Louf François , Gabsi Mohamed , Mermaz-Rollet Guillaume , Belhadi M’Hamed
Published: January 2023

The need of compact machines increased in recent years due to increases in raw materials’ price. Hence, many studies are currently being conducted on high-speed challenges to propose an optimal design methodology. AC losses in windings are often not included in the optimization process and are treated in post-processing by choosing a suitable conductor’s diameter to mitigate skin and proximity effects. This paper presents an optimization and design methodology for high-speed electric machines considering these losses, using models with an interesting trade-off between computation time and accuracy, which is helpful for large-scale optimization, in which more than 9,600,000 machines are evaluated. Optimizations are conducted on 100 kW high-speed one-layer V-shaped interior permanent magnet synchronous machines, widely used in vehicles thanks to their high power density, based on the specifications of the Peugeot e208, for different values of pole pairs and maximum speed. The influence of lamination thickness, fill factor, and maximum current density on the optimal design is also investigated. This paper concludes the utility of increasing speed to achieve high power density and proposes best alternatives regarding automotive constraints. Results show that the number of pole pairs is not always a key parameter in obtaining the lowest volume, especially at high speed.
Adaptive Hyperparameter Fine-Tuning for Boosting the Robustness and Quality of the Particle Swarm Optimization Algorithm for Non-Linear RBF Neural Network Modelling and Its Applications
Authors: Ahmad Zohaib , Li Jianqiang , Mahmood Tariq
Published: January 2023

A method is proposed for recognizing and predicting non-linear systems employing a radial basis function neural network (RBFNN) and robust hybrid particle swarm optimization (HPSO) approach. A PSO is coupled with a spiral-shaped mechanism (HPSO-SSM) to optimize the PSO performance by mitigating its constraints, such as sluggish convergence and the local minimum dilemma. Three advancements are incorporated into the hypothesized HPSO-SSM algorithms to achieve remarkable results. First, the diversity of the search process is promoted to update the inertial weight ω based on the logistic map sequence. Then, two distinct parameters are trained in the original position update algorithm to enhance the work efficiency of the successive generation. Finally, the proposed approach employs a spiral-shaped mechanism as a local search operator inside the optimum solution space. Moreover, the HPSO-SSM method concurrently improves the RBFNN parameters and network size, building a model with a compact configuration and higher precision. Two non-linear benchmark functions and the total phosphorus (TP) modelling issue in a waste water treatment process (WWTP) are utilized to assess the overall efficacy of the creative technique. The results of testing indicate that the projected HPSO-SSM-RBFNN algorithm performed very effectively.
Effect of Overburden Depth and Stress Anisotropy on a Ground Reaction Caused by Advancing Excavation of a Circular Tunnel
Authors: Lee Yu-Lin , Zhu Ming-Long , Ma Chi-Huang , Chen Chih-Sheng , Lee Chi-Min
Published: January 2023

The assumption of the Convergence–Confinement Method (CCM) is the analysis of the interaction behavior of the support and ground of a deep circular tunnel under an isotropic stress field. Aiming to improve this method, this paper proposes a discussion on the influence of the overburden depth and stress anisotropy. To consider the influence of the overburden effect, the ground reaction in different depths due to tunnel advancing excavation is investigated. Under anisotropic stress conditions, the analytical solutions of the stress/displacement in the plastic and elastic regions of this ground reaction can also be suitable for theoretical analysis in a consistent manner. The key factor in this study is the use of confinement loss, which can not only describe the simulation of tunnel advancing effects but also become a superimposed value of the incremental procedure. In addition, the calculation spreadsheets can be used to estimate and implement the theoretical analytical solutions into executable computational solutions. To check the validity of the analytical solution, finite element analysis is used to examine the distribution of stress/displacement around the tunnel, especially the distribution along the overburden pressure line in the circular tunnel cross-section. Comparing the analytical solution calculated by the incremental procedure with the result of the numerical analysis shows a consistent trend.
Constrained Nonsingular Terminal Sliding Mode Attitude Control for Spacecraft: A Funnel Control Approach
Authors: Xuan-Mung Nguyen , Golestani Mehdi , Hong Sung Kyung
Published: January 2023

This paper presents an adaptive constrained attitude control for uncertain spacecraft. Inspired by the concept of nonsingular terminal sliding mode control and funnel control for nonlinear systems, a novel adaptive attitude control is introduced which contains a time-varying gain to handle the constraints imposed on the spacecraft attitude. Indeed, when the attitude trajectory approaches the boundary of the constraint set, the control effort as well as the time-varying gain will increase in order to preclude the trajectory from intersecting the boundary. Then, it is analytically proved that the system trajectories converge to an arbitrary small region around the origin within a fixed time where the smallest upper bound of the convergence time is determined as an independent parameter in the controller. Further, the proposed control scheme is nonsingular without having to use any piecewise continuous function which simplifies stability analysis. These properties distinguish the proposed control scheme from the existing finite/fixed-time attitude controls. Finally, several simulation results confirm the robustness and performance of the proposed control framework.
Retaliation against Ransomware in Cloud-Enabled PureOS System
Authors: Ibrahim Atef , Tariq Usman , Ahamed Ahanger Tariq , Tariq Bilal , Gebali Fayez
Published: January 2023

Ransomware is malicious software that encrypts data before demanding payment to unlock them. The majority of ransomware variants use nearly identical command and control (C&C) servers but with minor upgrades. There are numerous variations of ransomware, each of which can encrypt either the entire computer system or specific files. Malicious software needs to infiltrate a system before it can do any real damage. Manually inspecting all potentially malicious file types is a time-consuming and resource-intensive requirement of conventional security software. Using established metrics, this research delves into the complex issues of identifying and preventing ransomware. On the basis of real-world malware samples, we created a parameterized categorization strategy for functional classes and suggestive features. We also furnished a set of criteria that highlights the most commonly featured criteria and investigated both behavior and insights. We used a distinct operating system and specific cloud platform to facilitate remote access and collaboration on files throughout the entire operational experimental infrastructure. With the help of our proposed ransomware detection mechanism, we were able to effectively recognize and prevent both state-of-art and modified ransomware anomalies. Aggregated log revealed a consistent but satisfactory detection rate at 89%. To the best of our knowledge, no research exists that has investigated the ransomware detection and impact of ransomware for PureOS, which offers a unique platform for PC, mobile phones, and resource intensive IoT (Internet of Things) devices.
Delayed Impulsive Control for μ-Synchronization of Nonlinear Multi-Weighted Complex Networks with Uncertain Parameter Perturbation and Unbounded Delays
Authors: Fan Hongguang , Tang Jiahui , Shi Kaibo , Zhao Yi , Wen Hui
Published: January 2023

The global μ-synchronization problem for nonlinear multi-weighted complex dynamical networks with uncertain parameter perturbation and mixed time-varying delays is investigated in this paper. Unlike other existing works, all delays, including sampling and internal and coupling delays, are assumed to be unbounded, making the considered model more general and practical. Based on the generalized impulsive comparison principles, a time-varying impulsive controller with sampling delays is designed, and some new sufficient conditions are obtained to make drive–response multi-weighted networks reach μ-synchronization. In addition, the external coupling matrices do not need to meet the requirement of zero-row sum, and the limitation of time delay on pulse interval is weakened. The results obtained in this article can be seen as extensions of previous related research.
Equation-Based Modeling vs. Agent-Based Modeling with Applications to the Spread of COVID-19 Outbreak
Authors: Kasereka Selain , Zohinga Glody , Kiketa Vogel , Ngoie Ruffin-Benoît , Mputu Eddy , Kasoro Nathanaël , Kyandoghere Kyamakya
Published: January 2023

In this paper, we explore two modeling approaches to understanding the dynamics of infectious diseases in the population: equation-based modeling (EBM) and agent-based modeling (ABM). To achieve this, a comparative study of these approaches was conducted and we highlighted their advantages and disadvantages. Two case studies on the spread of the COVID-19 pandemic were carried out using both approaches. The results obtained show that differential equation-based models are faster but still simplistic, while agent-based models require more machine capabilities but are more realistic and very close to biology. Based on these outputs, it seems that the coupling of both approaches could be an interesting compromise.
Endograph Metric and a Version of the Arzelà–Ascoli Theorem for Fuzzy Sets
Authors: Font Juan J. , Macario Sergio , Sanchis Manuel
Published: January 2023

In this paper, we provide several Arzelà–Ascoli-type results on the space of all continuous functions from a Tychonoff space X into the fuzzy sets of Rn, (FUSCB(Rn),Hend), which are upper semi-continuous and have bounded support endowed with the endograph metric. Namely, we obtain positive results when X is considered to be a kr-space and C(X,(FUSCB(Rn),Hend)) is endowed with the compact open topology, as well as when we assume that X is pseudocompact and C(X,(FUSCB(Rn),Hend)) is equipped with the uniform topology.
Soot Formation in Spherical Diffusion Flames
Authors: Frolov Sergey M. , Ivanov Vladislav S. , Frolov Fedor S. , Vlasov Pavel A. , Axelbaum Richard , Irace Phillip H. , Yablonsky Grigoriy , Waddell Kendyl
Published: January 2023

In the period from 2019 to 2022, the joint American–Russian space experiment (SE) Flame Design (Adamant) was carried out on the International Space Station (ISS). The purpose of the joint SE was to study the mechanisms of control of soot formation in a spherical diffusion flame (SDF) formed around a porous sphere (PS), and the radiative extinction of the SDF under microgravity conditions. The objects of this study were “normal” and “inverse” SDFs of gaseous ethylene in an oxygen atmosphere with nitrogen addition at room temperature and pressures ranging from 0.5 to 2 atm. A normal flame is a flame formed in an oxidizing atmosphere when fuel is supplied through the PS. An inverse flame is a flame formed in a fuel atmosphere when an oxidizer is introduced through the PS. This article presents the results of calculations of soot formation in normal and inverse SDFs. The calculations are based on a one-dimensional non-stationary model of diffusion combustion of gases with detailed kinetics of ethylene oxidation, supplemented by a macrokinetic mechanism of soot formation. The results indicate that soot formation in normal and inverse SDFs is concentrated in the region where the local C/O atomic ratio and local temperature satisfy the conditions 0.32 < C/O < 0.44 and T > 1300–1500 K.
Principal Solutions of Recurrence Relations and Irrationality Questions in Number Theory
Authors: Mingarelli Angelo B.
Published: January 2023

We apply the theory of disconjugate linear recurrence relations to the study of irrational quantities in number theory. In particular, for an irrational number associated with solutions of linear three-term recurrence relations, we show that there exists a four-term linear recurrence relation whose solutions show that the number has an irrational square if and only if the four-term recurrence relation has a principal solution of a certain type. The result is extended to higher-order recurrence relations, and a transcendence criterion can also be formulated in terms of these principal solutions. The method generates new series expansions of positive integer powers of ζ(3) and ζ(2) in terms of Apéry’s now classic sequences.
Effect of Future Price Increase for Products with Expiry Dates and Price-Sensitive Demand under Different Payment Policies
Authors: Jani Mrudul Y. , Betheja Manish R. , Chaudhari Urmila , Sarkar Biswajit
Published: January 2023

The current study works with an inventory management strategy under the discount cash flow approach for perishable commodities with expiry dates, price-sensitive demand, and investment in preservation technology. In addition, this study examines the probable influence of price-increase on the replenishment strategy of the retailer where specific delivery units can be purchased. Furthermore, in this model, two circumstances are deliberated: (I) when the time of the specific delivery matches with the reordering time of the retailer or (II) when the time of the specific delivery emerges within the duration of the sale. Before the price increase, the supplier provides two payment policies to the retailer from which they can choose one. The policies are either: (1) a permissible delay in payment on regular orders or (2) a discount in payment for the specific delivery. The key goal is to optimize the overall profit for the retailer with respect to the sales price, investment in preservation technology, and cycle time during the depletion time of the specific delivery. In addition, an algorithm is created to optimize the results and seven numerical illustrations are discussed to explain the results along with the special case. Finally, to display the pertinence of this model, a sensitivity analysis of the main parameters is performed with important managerial implications. The key findings of this research are (1) before the price increase, the retailer gets the maximum profit if the retailer chooses a discount in payment policy on the specific delivery; (2) how much to order from the supplier and when to place a specific delivery to generate a maximum profit; and (3) the price-sensitive demand and assumption of future price increase negatively affect the retailer’s overall profit, and the retailer gets maximum benefits if the retailer initially orders the maximum number of units from the supplier before the price increase.
Int N-Soft Substructures of Semigroups
Authors: Shabir Muhammad , Mushtaq Rimsha , Jawad Muhammad , Naz Munazza , Jarad Fahd , Abdeljawad Thabet
Published: January 2023

The N-soft sets are newly defined structures with many applications in the real world. We aim for combining the semigroup theory and N-soft sets to provide a comprehensive account of the hybrid framework of N-soft Semigroups. In this paper, we define the γ-inclusive set, int N-soft subsemigroups, int N-soft left [right] ideals of S, int N-soft product and int N-soft characteristic function, θ-Generalized int N-soft subsemigroups and θ-Generalized int N-soft left [right] ideals of S. We also discuss some examples and theorems based on the restricted (extended) union, restricted (extended) intersection, and γ-inclusive set.
Stability Results for a Weakly Dissipative Viscoelastic Equation with Variable-Exponent Nonlinearity: Theory and Numerics
Authors: Al-Mahdi Adel M. , Al-Gharabli Mohammad M. , Noor Maher , Audu Johnson D.
Published: January 2023

In this paper, we study the long-time behavior of a weakly dissipative viscoelastic equation with variable exponent nonlinearity of the form utt+Δ2u−∫0tg(t−s)Δu(s)ds+a|ut|n(·)−2ut−Δut=0, where n(.) is a continuous function satisfying some assumptions and g is a general relaxation function such that g′(t)≤−ξ(t)G(g(t)), where ξ and G are functions satisfying some specific properties that will be mentioned in the paper. Depending on the nature of the decay rate of g and the variable exponent n(.), we establish explicit and general decay results of the energy functional. We give some numerical illustrations to support our theoretical results. Our results improve some earlier works in the literature.
A Concise Review on the Potential Applications of Rugulopteryx okamurae Macroalgae
Authors: Barcellos Ligia , Pham Christopher , Menezes Gui , Bettencourt Raúl , Rocha Nieta , Carvalho Miguel , Felgueiras Helena
Published: January 2023

The brown macroalgae of the species Rugulopteryx okamurae has reached European waters and the Strait of Gibraltar as an invasive species. The proliferation and colonization of the species in subtidal and intertidal zones of these regions imposes significant threats to local ecosystems and additionally represents a significant socioeconomic burden related to the large amounts of biomass accumulated as waste. As a way to minimize the effects caused by the accumulation of algae biomass, investigations have been made to employ this biomass as a raw material in value-added products or technologies. The present review explores the potential uses of R. okamurae, focusing on its impact for biogas production, composting, bioplastic and pharmaceutical purposes, with potential anti-inflammatory, antibacterial and α-glucosity inhibitory activities being highlighted. Overall, this species appears to present many attributes, with remarkable potential for uses in several fields of research and in various industries.
Type-I Hemins and Free Porphyrins from a Western Australian Sponge Isabela sp.
Authors: Sala Samuele , Moggach Stephen , Nealon Gareth , Fromont Jane , Gomez Oliver , Vuong Daniel , Lacey Ernest , Flematti Gavin
Published: January 2023

Two novel free porphyrins, isabellins A and B, as well as the known compounds corallistin D and deuteroporphyrin IX were isolated from a marine sponge Isabela sp. LC-MS analysis of the crude extract revealed that the natural products were present both as free porphyrins and iron(III) coordinated hemins, designated isabellihemin A, isabellihemin B, corallistihemin D and deuterohemin IX, respectively. Structures were determined via high-resolution mass spectrometry, UV-Vis spectroscopy and extensive NOESY NMR spectroscopic experiments. The type-I alkyl substitution pattern of isabellin A and isabellihemin A was assigned unambiguously by single crystal X-ray diffraction. Biological evaluation of the metabolites revealed potent cytotoxicity for isabellin A against the NS-1 murine myeloma cell line.
Effect of Rowachol on the Gallbladder Dysmotility Disorder Based on Gallbladder Ejection Fraction
Authors: Lee Sang Hoon , Chung Hyun Woo , Lee Tae Yoon , Cheon Young Koog
Published: January 2023

Background and Objectives: Although laparoscopic cholecystectomy is the preferred treatment method in patients who experience typical biliary pain with or without gallstones, medical treatment has not been extensively studied. Rowachol is a potent choleretic agent, comprising six cyclic monoterpenes. This study aimed to investigate the clinical improvement and changes in gallbladder ejection fraction (GBEF) by Rowachol treatment in patients with typical biliary pain. Materials and Methods: We retrospectively reviewed 138 patients with typical biliary pain who underwent cholescintigraphy from July 2016 to April 2022. We included patients who received Rowachol for more than 2 months and underwent follow-up GBEF measurements. Finally, we analyzed pre- and post-treatment symptoms and GBEF. GBEF was calculated using the fatty meal-stimulated cholescintigraphy. Results: This retrospective observational study included 31 patients; their median age was 46.0 (range, 26.0–72.7) years, and 22 (71.0%) were female. Overall, 9 (29.0%) patients had gallbladder stones or sludges (maximum size: 2 mm) on initial transabdominal ultrasonography. During a median follow-up of 23.3 months, the symptoms of 21 (67.7%) patients were resolved after a median Rowachol treatment of 10.0 months. The mean GBEF was significantly improved after Rowachol treatment (initial cholescintigraphy: 42.6% ± 16.2%; follow-up cholescintigraphy: 53.0% ± 18.1%, p = 0.012). In patients with a GBEF ≤35% (n = 9), Rowachol significantly increased the GBEF from 21.3% ± 8.3% to 49.1% ± 20.7% (p = 0.008). Conclusions: Rowachol may have beneficial medical effects that can improve gallbladder dysfunction and treatment response.
Associations between Vitamin D Deficiency and Carbohydrate Intake and Dietary Factors in Taiwanese Pregnant Women
Authors: Lin Chao-Hsu , Lin Pei-Shun , Lee Meei-Shyuan , Lin Chien-Yu , Sung Yi-Hsiang , Li Sung-Tse , Weng Shun-Long , Chang Shing-Jyh , Lee Hung-Chang , Lee Yann-Jinn , Chang Hung-Yang , Lin Chih-Sheng
Published: January 2023

This cross-sectional observation study investigated the vitamin D (VD) status in Taiwanese pregnant women and the effects of VD supplementation and macronutrient intake on serum 25-hydroxy-vitamin D (25[OH]D) level. Data on VD intake, daily sunlight exposure, and carbohydrate intake were obtained from 125 pregnant women at 30–37 weeks’ gestation. Serum 25[OH]D level was measured before delivery in all enrolled women; and the mean 25(OH)D level was 43 nmol/L or 17.2 ng/mL. The 25(OH)D level was significantly correlated with total VD intake of pregnant women (r = 0.239; p = 0.007). The severe VD deficiency group (n = 16; mean of 25(OH)D level = 8.5 ng/mL) had significantly lower total VD intake and supplementation than the groups with VD deficiency (n = 69), insufficiency (n = 32), and sufficiency (n = 8). Those with ≥400 IU/day total VD intake (including VD from food and supplementation) had significantly higher 25(OH)D concentration than those with <400 IU/day total VD intake. Those with 400 IU/day VD supplementation could significantly increase serum 25(OH)D concentrations for pregnant women. Among 85 pregnant women with carbohydrate intake of ≥300 g/day, serum 25(OH)D levels were negatively correlated with carbohydrate intake (p = 0.031). In conclusion, VD deficiency was highly prevalent in Taiwanese pregnant women. VD supplementation was the most effective method for increasing 25(OH)D concentration in pregnant women. Higher carbohydrate intake might reduce 25(OH)D levels.
Different Liquid Biopsies for the Management of Non-Small Cell Lung Cancer in the Mutational Oncology Era
Authors: Palmieri Maria , Frullanti Elisa
Published: January 2023

In the last ten years, liquid biopsy has been slowly joining the traditional invasive techniques for the diagnosis and monitoring of tumors. Liquid biopsies allow easy repeated sampling of blood, reflect the tumor scenario, and make personalized therapy real for the patient. Liquid biopsies isolate and utilize different substrates present in patients’ body fluids such as circulating tumor cells, circulating tumor DNA, tumor extracellular vesicles, etc. One of the most-used solid cancers in the development of the non-invasive liquid biopsy approach that has benefited from scientific advances is non-small cell lung cancer (NSCLC). Using liquid biopsy, it is possible to have more details on NSCLC staging, progression, heterogeneity, gene mutations and clonal evolution, etc., basing the treatment on precision medicine as well as on the screening of markers for therapeutic resistance. With this review, the authors propose a complete and current overview of all different liquid biopsies available to date, to understand how much has been carried out and how much remains to be completed for a better characterization of NSCLC.