bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification Of Nutritional Adequacy Of Pregnant Women With The Figo Nutrition Checklist
Authors: Hanifah Dewi
Published: February 2024

Latar Belakang: Gizi dalam kehamilan mempunyai implikasi penting terhadap kesehatan ibu dan anak. Gizi selama kehamilan yang optimal, akan mendorong pertumbuhan dan perkembangan janin yang optimal.Tujuan: Mengidentifikasi kecukupan zat gizi pada ibu hamil di Puskemas Kota Sukabumi dan mengidentifikasi kelompok ibu hamil yang beresiko mengalami masalah giziMetode : Desain penelitian analitik observasional dengan pendekatan cross sectional menggunakan data primer dengan mengukur kecukupan gizi ibu hamil dengan instrumen FIGO Nutrition Checklist. Sampel dalam penelitian ini sebanyak 65 orang dengan teknik pengambilan sampel menggunakan consecutive sampling. Penelitian dilaksanakan di Puskesmas PONED Sukabumi pada bulan Juli – September 2022. Analisis data menggunakan Chi Square.Hasil: Masih terdapat ibu hamil dengan status gizi kurang (7,7%) dan status gizi lebih (30,8%). Hanya 20% ibu hamil dengan kualitas diet memenuhi indikator instrumen FIGO Nutrition Checklist. Variasi jenis makanan yang dikonsumsi ibu hamil belum memenuhi kebutuhan diet yang disarankan. Faktor demografi yang berhubungan dengan kualitas diet adalah pendidikan ibu (p<0,05).   Kesimpulan: Kebutuhan gizi selama kehamilan belum memenuhi indikator FIGO Nutrition Checklist, terdapat ibu hamil dengan gangguan nutrisi.Saran: Perlu dilakukan edukasi gizi terhadap ibu hamil melalui pelayanan antenatal. Kata Kunci: FIGO,Nutrition, Checklist ABSTRACT Background: A balanced diet during pregnancy is crucial for optimal fetal growth and development.Objective: This study aims to assess the nutritional adequacy of pregnant women attending the Sukabumi Public Health Center and identify groups of pregnant women at risk of nutritional problems.Methods: This observational study used the FIGO Nutrition Checklist to measure the nutritional adequacy of 65 pregnant women at the Sukabumi Public Health Center from July to September 2022, using chi-square for data analysis.Results: The study found that some pregnant women suffered from undernutrition (7.7%) and overnutrition (30.8%). Only 20% of pregnant women met the indicators of the FIGO Nutrition Checklist instrument, indicating that their diet quality was appropriate. The study also revealed that the variety of foods consumed by pregnant women did not meet the recommended dietary needs. Maternal education was found to be associated with diet quality (p<0.05).Conclusion: The results suggest that pregnant women's nutritional needs are not being met according to the FIGO Nutrition Checklist indicators, and some women are experiencing nutritional disorders.Suggestion: It is recommended that antenatal care should include nutrition education for pregnant women to ensure that they receive adequate nutrition during pregnancy. Keywords: FIGO, Nutrition,Checklist
Kisagyi abiotrophia border collie kutyafajtában
Authors: Molnár Ticiána , Emri Zsuzsanna , Antal Károly
Published: February 2024

A cerebelláris abiotrófia (CA) különböző kisagyi neurontípusok korai, progresszív degenerációját eredményezi. A border collie fajta népszerűségével a CA előfordulási gyakorisága nő. Gyógymód még nem áll rendelkezésre, az érintett állatoknak általában 6 hónapos koruktól az életminősége drasztikusan romlik, és eutanáziát hajtanak rajtuk végre. Kutatásunkban adatokat gyűjtöttünk border collie egyedekről: származásáról, betegségeiről és azok tüneteiről egy kérdőív segítségével. A kérdőívet tulajdonosok, tenyésztők és állatorvosok is kitöltötték. Hat magyarországi CA-ban szenvedő egyednél kognitív tesztet végeztünk, és összehasonlítottuk eredményeiket hat hasonló korú kontrollállat eredményeivel. A tanulmány célja az, hogy (1) összefoglalja a border collie-kkal készített, a CA tüneteivel és manifesztációjával kapcsolatos felmérés eredményeit, és (2) a CA-ban szenvedő kutyák kognitív károsodását. Kognitív teszteket eddig nem alkalmaztak a CA-val rendelkező border collie-kon. A felmérést 1587-en töltötték ki, és 55 esetet jelentettek. A tünetek hasonlóak voltak, és a 4-5 hetes kölyköknél már felismerhetően jelentkeztek. Mindkét nem érintett volt. A kognitív tesztek a szaglás és a látás károsodását mutatták ki, de a hallási percepciót vagy a figyelmet a CA nem károsította. A CA-kutyáknak több időre volt szükségük a memóriateszteken a feladat elvégzéséhez. A CA-kutyák feltárt kognitív működési zavara segítheti a betegség korai felismerését, új részleteket tár fel a betegség kialakulásáról és lefolyásáról, ezáltal támogatja a további kutatásokat.
Környezeti nevelés: Esettanulmány az Eszterházy Károly Katolikus Egyetem Botanikus Kertjének példáján
Authors: Horotán Katalin , Táborská Jana
Published: February 2024

A botanikus kertek jelentős növénygyűjteményeket őriznek és gondoznak. A növényfajok megőrzése mellett oktatási, kutatási és rekreációs funkciójuk is kiemelkedő. Ezeknek a funkcióknak a sikeres megvalósítása nemcsak amiatt fontos, mert ezek a programok fontos bevételi források lehetnek, hanem azért is, mert terjesztik városi környezetben a kertépítéshez, kertészkedéshez szükséges ismereteket, ösztönzik a közösségi, iskolai kertek kialakítását. Jelen tanulmányunkban a botanikus kertekben zajló környezeti nevelési foglalkozások tervezési és előkészítési folyamatát és megvalósítását mutatjuk be az Eszterházy Károly Katolikus Egyetem (EKKE) Botanikus Kertjének példáján. A botanikus kert növényállományából a gyógy- és fűszernövényeket helyeztük a középpontba. A foglalkozások tematikáját, céljait és lehetséges megvalósítási módszereit a korosztályok szerinti bontásban, az iskolai tananyag, a résztvevők érdeklődési köre és a befogadási képessége alapján határoztuk meg. Három olyan foglalkozást mutatunk be röviden, melyek olyan növényállományra támaszkodnak, melyek nem csupán a botanikus kertekben, hanem iskolai intézménykertekben és közösségi kertekben egyaránt telepíthetőek, és így ezek a foglalkozások ott is megvalósíthatók.
Regulation Learning Qur’an: Upaya Membangun Kemandirian Belajar Abad 21
Authors: Lutfi Saiful , Surawan Surawan , Zanuba Adisty Arselia
Published: February 2024

Penelitian ini dilatar belakangi oleh fenomena yang terjadi dilapangan, peneliti melihat sebagian remaja di Desa Ruwuk Ranggan kurang memperhatikan tanggung jawab intelektualnya, khususnya dalam pembelajaran Al-Qur’an. Penelitian ini bertujuan untuk mendeskripsikan tentang self-regulated learning pada remaja di Desa Ruwuk Ranggan Kecamatan Cempaga Kabupaten Kotawaringin Timur. Penelitian ini menggunakan pendekatan kualitatif deskriptif  dengan teknik pengumpulan data menggunakan observasi, wawancara, dan dokumentasi. Hasil penelitian ini didapatkan bahwa mayoritas remaja di Desa Ruwuk Ranggan memiliki self-regulated learning yang rendah, terkhusus dalam belajar Al-Qur’an secara mandiri, namun ada juga sebagian remaja yang memiliki self-regulated learning yang tinggi. self-regulated learning pada remaja dalam belajar Al-Qur’an dipengaruhi oleh beberapa faktor pendukung yaitu; 1) keyakinan diri (Self efficacy), 2) motivasi diri (Self-motivation), 3) dukungan sosial.
Pembelajaran Pembuatan Pakan Mandiri dan Penstimulan Moulting Udang bagi Pembudidaya Tradisional
Authors: Heriansah Heriansah , Nursyahran Nursyahran , Fathuddin Fathuddin , Kabangnga Arnold , Najamuddin Najamuddin
Published: February 2024

Shrimp farming in Indonesia is dominated by traditional cultivation methods, therefore they do not have sufficient financial access to obtain expensive commercial feed. The Program for Application of Appropriate Technology (PTTG) aims to provide lessons on making independent feed and stimulating shrimp moulting for traditional farmers in Ma'rang District, Pangkajene and Islands Districts using local raw materials. The Participatory Rural Appraisal (PRA) approach model, which emphasizes the active involvement of the community in all activities, is used in this program. The knowledge and skills transferred from this study include the concept of artificial feed and moulting, preparation of raw materials, preparation of feed composition, mixing and weighing of raw materials, and pelleting and supplementation of feed. The results of the pre-test showed that the level of knowledge and skills regarding self-sufficient feed production and the manufacture of moulting-stimulating ingredients were generally in the poor category. However, after the learning activities, the post-test results showed that the level of knowledge and skills increased significantly and was generally in the good category. In general, partners believe that learning items are technically easy to apply, economically inexpensive, and ecologically can reduce agricultural and fishery waste. The lessons learned by traditional cultivators through this program can be utilized optimally in increasing production.
Pemberdayaan kesehatan masyarakat Desa Gunung Manik Melalui Potensi Desa Budidaya Madu
Authors: Kunaedi Aan , Lestari Trisna , Johan Johan , Utami Arie Susetio , Prasetyo Tri Budi , Andriana Andriana , Angela Elva
Published: February 2024

The abundant natural potential of Gunung Manik has not been optimally utilized. The support of the village apparatus to continue to improve village welfare makes the development of villages and residents quite fast in receiving positive information from outside. Natural potential can be further optimized, one of which is by developing honey cultivation, which has great potential with the support of available natural resource conditions. Activities are carried out using counseling methods and interactive directly to measure the level of pre-activity knowledge and understanding in the people of Gunung Manik Village, descriptive material presentation through interactive so that the implementation of activities is more active and avoids boredom. The results of the activity can be seen from increasing community insight into health, That is benefits of honey on health and the enthusiasm of community for honey cultivation as an effort to improve the economy and health of the people of Gunung Manik Village, Ciniru Kuningan.
Penyuluhan Penggunaan Lampu Navigasi Pada Kapal Nelayan Desa Wawontulap Untuk Menghindari Bahaya Tubrukan di Laut
Authors: Silalahi Aliong , Irawan Santun , Frastika Yustiani
Published: February 2024

Risks of transportation safety are still a common issue in Indonesia. Communities living in coastal and marine areas, the majority of whom work as fishermen, still rely on traditional knowledge and skills. Wawontulap Village is located in the Tatapaan District with a total of 80 active fishermen, most of whom use small-scale traditional fishing boats with 50 cc to 80 cc motor engines and without adequate navigation tools, thus impacting visibility for ship maneuvers. fisherman. The position and potential for catching larger fish at night is a challenge for the fishing community in Wawontulap Village. This is because at night many fishing or fishing boats with larger sizes also descend into the sea which can cause a collision hazard between ships. The problem of navigation tools in the form of navigation lights is deemed necessary to find a solution immediately. Navigation lights on board apart from functioning as navigation guides can also be used as lighting and communication tools in the form of light signals if fishermen need help at any time. the method of socialization and delivery of assistance in the form of 3 (three) navigation lights which were handed over symbolically to village officials (the old law). From this community service activity it shows that fishermen's knowledge of the importance of navigation lights becomes clear and the danger of ship collisions when fishermen go outside to catch fish can be avoided.
Pendampingan Guru Sekolah Dasar Dalam Pelaksanaan Pembelajaran Berdiferensiasi pada Komunitas Belajar Kelompok Kerja Guru Di Kota Palangka Raya
Authors: Eshariyani Eshariyani , Ernawatie Ernawatie , Berliani Teti , Sumarnie Sumarnie , Nugroho Piter Joko , Limin Dagai L , Aprianto Aprianto , Purnomo Widiharto , Winaryo Slamet , Radiafilsan Christian , Sedek Melky
Published: February 2024

To support Indonesia's educational vision, and as part of efforts to restore learning, the Merdeka Curriculum was developed as a curriculum framework that is more flexible, while also focusing on essential material and developing students' character and competencies. Through the application of differentiated learning, students will not only be able to maximize their potential, but they can also learn about various important life values ​​that will contribute to their development in a more holistic or complete manner. Differentiated learning is learning that is rooted in meeting the needs of students both in terms of learning readiness, interest, or learning profile and how the teacher responds to these learning needs. This community service activity is carried out with the aim of providing assistance and guidance to teachers, especially at the elementary school level so that they can develop differentiated learning and its application in the classroom, so that student-centered learning activities can be carried out properly. The method of implementing community service activities is carried out by: (1) theoretical socialization related to differentiated learning for teachers; (2) workshops on the application of differentiated learning; and (3) assistance and guidance in organizing differentiated learning in the classroom based on the Freedom to Learn curriculum. The results of this PkM activity are: (1) teachers gain additional knowledge related to differentiated learning; (2) teachers can prepare Differentiated Learning Implementation Plans; and (3) teachers are capable of carrying out differentiated learning at all grade levels, especially at the elementary school level.
Cardiac autonomic regulation in response to functional power threshold testing in elite cyclists.
Authors: Castillo-Aguilar Matías , Mabe-Castro Diego , Mabe-Castro Matías , Oyarzo Valeska , Harris King Katherine , Valdés-Badilla Pablo , Delgado-Floody Pedro , González-Puelma Jorge , Núñez Espinosa Cristian Andrés
Published: February 2024

Objective: To evaluate the impact of a functional power threshold test (FTP) on cardiac autonomic regulation indicators in high performance cyclists.

Methods: A total of 12 male elite cyclists (mean age 36.1 ± 11.2 years) were recruited. Body composition parameters were measured using bioimpedancemetry and heart rate variability (HRV) before and after the application of the FTP assessment.

Results: We observed that a greater sympathetic nervous system (SNS) index and Stress index on baseline were correlated with a smaller decrease in the parasympathetic nervous system (PNS) activity in response to the FTP test (rho = 0.69, p = 0.013). Concerning morphological parameters, the skeletal muscle index (SMI) was the only one that was inversely correlated with ∆PNS (rho = -0.69, p = 0.02) whereas the muscle-bone index (MBI) displayed a positive correlation with ∆SNS (rho = 0.82, p = 0.001). In fully adjusted models we found that waist-to-hip ratio (beta = 7.90, CI95%[4.16, 11.63], t(8) = 4.88, p = 0.001) and SMI significantly influenced ∆PNS (beta = -1.38, CI95%[-1.84, -0.92], t(8) = -6.94, p < 0.001), whereas MBI (beta = 10.26, CI95%[8.10, 12.42], t(8) = 10.96, p < 0.001) and the interaction between the latter and Power achieved during FTP influenced ∆SNS (beta = -0.05, CI95%[-0.09, -4.99e-03], t(8) = -2.56, p = 0.033).

Conclusion: Our findings indicate that the SMI had a negative effect on the ∆PNS, while the MBI was positively correlated with the ∆SNS in cyclists. These findings suggest that a higher SMI and MBI could have a detrimental impact on the cardiac autonomic response to maximal aerobic exercise in high-performance cyclists, such as FTP.
REGENERASI PERWIRA PENERBANG ANGKATAN DARAT
Authors: Awwaluddin A. , Ali Yusuf , Arman Andi
Published: February 2024

This study aims to analyze the optimal strategy in improving the regeneration of Indonesian Army (TNI AD) aviator officers to support the tasks of the Army. In this evolving era, the Indonesian Army faces complex challenges that require strong regeneration in its personnel, especially in terms of flight officers who have an important role in supporting military operations and national defense. The research method used in this research is a qualitative method with a descriptive analysis approach. The data used consisted of literature, policy documents, and interviews with relevant parties within the Army. The results of the analysis show that there are several strategies that can be applied to improve the regeneration of TNI AD flight officers. Among them are improving selection and recruitment by involving a comprehensive assessment of physical abilities, intelligence, leadership and relevant technical skills, developing effective education and training programs that involve a combination of academic education with intensive and realistic field exercises, developing adequate infrastructure and facilities for flight training, and a clear and sustainable career development program for flight officers. In order to improve the regeneration of Indonesian Army flight officers, the implementation of these strategies needs to be supported by a strong commitment from the government and related institutions. Through a holistic and sustainable approach, it is hoped that the Army can have a strong regeneration of aviator officers who are ready to face increasingly complex tasks in the future
DEVELOPING SELF-RELIANCE IN THE DEFENSE INDUSTRY
Authors: Sutanto Rudy , Priyanto Priyanto
Published: February 2024

Sektor pertahanan merupakan landasan yang sangat penting, yang tidak hanya mencerminkan kekuatan militer tetapi juga kapasitas teknologi dan industri suatu negara. Di kawasan ASEAN, pentingnya industri pertahanan yang mandiri menjadi hal yang terpenting mengingat beragamnya sifat negara-negara anggota dan tujuan bersama dalam menjaga stabilitas regional. Artikel ini berupaya memahami jalan menuju otonomi di sektor pertahanan bagi negara-negara ASEAN. Dengan mengadopsi metodologi penelitian kualitatif, studi ini menyelidiki faktor-faktor mendasar yang mempengaruhi kemandirian dalam industri pertahanan. Tujuan inti dari penelitian ini adalah untuk memahami pendorong mendasar yang mendorong negara-negara untuk mencapai kemandirian dalam industri pertahanan. Laporan ini mengungkap tantangan-tantangan seperti ketergantungan teknologi, kendala keuangan, dan hambatan kebijakan. Namun, muncul strategi-strategi potensial yang mendorong inovasi, kolaborasi intra-ASEAN, dan peran pendidikan dalam mendorong kemandirian. Rekomendasi-rekomendasi diberikan, yang menggarisbawahi pentingnya visi dan strategi pertahanan terpadu untuk meningkatkan kemampuan pertahanan kolektif ASEAN. Upaya mencapai otonomi pertahanan bukan sekadar unjuk kehebatan militer, melainkan cerminan aspirasi ASEAN untuk kemandirian regional, inovasi teknologi, dan kemajuan ekonomi. Jalan menuju kemandirian dalam industri pertahanan sangatlah rumit dan menantang, investasi strategis, kolaborasi, dan berbagi pengetahuan dapat memfasilitasi realisasi tujuan penting ini. Menerapkan strategistrategi ini tidak hanya menjamin otonomi militer tetapi juga mendorong persatuan regional, kemajuan teknis, dan pertumbuhan ekonomi
THE EVOLUTION AND INSTITUTIONALIZATION OF THE NAVAL PARTNERSHIP BETWEEN INDONESIA AND ASEAN
Authors: Komalasari Rita , Mustafa Cecep
Published: February 2024

This essay explores the evolution and institutionalization of the naval partnership between Indonesia and the Association of Southeast Asian Nations (ASEAN). The background reveals the maritime challenges faced by these entities in the dynamic Asia-Pacific region, necessitating collaborative security efforts. The purpose of the study is to analyze how this naval relationship has developed over time and its impact on regional maritime stability. The design/methodology/approach encompasses historical analysis, policy examination, and case studies of joint naval exercises. The results demonstrate that Indonesia and ASEAN's naval partnership has evolved from historical precedents to structured cooperation, incorporating joint exercises, information sharing, and capacity building. This collaboration contributes to regional maritime security and exemplifies the collective approach to addressing common challenges. In conclusion, this essay underscores the significance of such partnerships in shaping maritime security dynamics and promoting stability in an increasingly interconnected world.
AMPHIBIOUS FORCES IN THE TOTAL WAR AGE: EXPLORING INDONESIA'S MULTIFACETED CONTRIBUTIONS TO STATECRAFT IN THE ASIA-PACIFIC REGION
Authors: Komalasari Rita , Mustafa Cecep
Published: February 2024

This paper explores the roles and functions of Indonesian amphibious forces in the Asia-Pacific region, offering insights into their legal foundations, contemporary relevance, and multifaceted contributions to statecraft. The primary purpose of this paper is to provide a comprehensive analysis of Indonesia's amphibious forces, serving as a case study to illuminate their evolving significance in the total war age. By examining the legal protections, contemporary utilization, and strategic implications of these forces, this study aims to fill existing gaps in the literature and offer valuable insights for scholars, policymakers, and military strategists. Methodology: This research employs literature study. Result/Conclusion: The analysis reveals that legal foundations play a crucial role in the development of amphibious forces, with Indonesia's constitutional legislation serving as a key enabler. These forces serve as potent tools for power projection, deterrence, humanitarian assistance, and disaster relief. Furthermore, they contribute to Indonesia's foreign policy objectives and diplomatic initiatives in the Asia-Pacific region. This paper underscores the continued relevance of amphibious forces in modern warfare and highlights Indonesia's effective utilization as a case study. Ultimately, it provides a comprehensive understanding of their multifaceted contributions to statecraft in the total war age, with implications for scholars, policymakers, and military strategists seeking to navigate the complexities of contemporary security dynamics.
Design and calculation of cold storage capacity of 10 tons for tuna commodity
Authors: Syafar Pramudya Doni , Pamitran Agus Sunjarianto , Ardiyansyah Ardiyansyah , Budiyanto Muhammad Arif
Published: February 2024

The Ministry of Maritime Affairs and Fisheries, Republic of Indonesia, urges economic stakeholders to maximize increasingly open export opportunities. With an abundance of fishery products in Indonesian waters, it must be supported by adequate facilities, one of which is the availability of cold storage, which maintains the quality of fishery products. In this study, the design of the cold storage was carried out by measuring the size of the cold storage and using the calculation of the cooling load, the calculation of cooling capacity, the calculation of the P-h diagram, and the cost estimate. The results of this study include cold storage design dimensions of 420 m3 with a long length and tall of 15×7×4 m3 made from insulation materials of polyurethane, stainless steel, and plaster. The cooling load data for the cold storage, when the product (tuna) is cooled and filled, is 3,707,444.3 kJ every 24 hours. A ton of refrigeration absorbs 12,660 kJ per 24 hours, equaling 16.3 tons of required refrigeration capacity. Meanwhile, under normal operating conditions, the total cooling load is 759,427.588 kJ per 24 hours. After calculating the cooling load, it was discovered that the initial design, which only had a capacity of 10 tons during the refrigeration process, could accommodate a cooling capacity of up to 16.3 tons. The cooling capacity of cold storage is 23.9 kW or 81.400 Btu/h. P-h diagram calculation of compressor cooling load is 0.7 kW, and the cooling load total from the evaporator to keep air room temperature of cold storage 0 °C is 0.43 kW. Estimated cost total for materials of cold storage design is USD 128,655.
Highlights

Refrigerator facilities are still limited in reaching remote coastal areas
The cooling system must start using renewable energy
Cold storage is used to maintain the quality of fishery product so that they remains in good condition
From the calculation results, knowing the total cooling load when the cold storage is working, knowing the total cooling capacity of the cold storage when it is used as a fish storage refrigerator, and knowing the total estimated operational costs of the cold storage
Adenovirus-associated thrombosis and thrombocytopenia: an emerging anti-PF4 disorder
Authors: Song Andrew B. , Al-Samkari Hanny
Published: February 2024

Not available.
Anatomy of a crime: how IL7R and NRAS join forces to drive T-cell acute lymphoblastic leukemia
Authors: Barata João T.
Published: February 2024

Not available.
CT Imaging of Colonic Lipomas: Case Report and Literature Review
Authors:   Ospedale Sacro Cuore di Gesù FBF, Benevento, Italy, Fontanella Giovanni ,   Hillman Cancer Center 'Villa Maria', Mirabella Eclano, Italy,   A.O.R.N ' S.G. Moscati', Avellino, Italy, Borrelli Simona , Brogna Barbara
Published: February 2024

Although gastrointestinal lipomas are a rare finding on radiologic examinations, their frequency is high enough to suggest taking them into account when making a differential diagnosis for mass lesions of the bowel. Their morphology, peculiar density on CT and intensity on MRI scans, frequently allow to suspect the presence of a lipoma.
STRATEGIC DECISION MAKING IN A HETEROGENEOUS AND UNCERTAIN BUSINESS ENVIRONMENT: INTEGRATED MODELS FOR ANALYSIS AND FORECASTING
Authors: SUVOROVA SVITLANA , PYLYPENKO MAKSYM , TOLPEZHNIKOV ROMAN , KOVTUN OLENA , TSEBRO YANA
Published: February 2024

This article provides a comprehensive examination of models employed in strategic decision-making within a context characterized by heterogeneity and uncertainty in the business environment. It elucidates prominent theories and methodologies utilized for the identification, analysis, and response to diverse economic, social, and technological factors influencing the market environment. The discourse encompasses the evolution in strategic decision-making paradigms, encompassing transitions towards scenario planning, the delicate equilibrium between intuitive approaches and analytical methodologies, and the organizational adaptation to internal variations. The research methodology proposed herein is grounded in a systematic approach, emphasizing analysis and synthesis. The article directs its focus towards diverse integrative analysis models that amalgamate internal and external facets of organizations, facilitating efficacious strategic decision-making. The scrutiny of models such as the Ansoff Matrix, Porter's Five Forces, McKinsey 7S Model, and BCG Growth-Share Matrix reveals that each model possesses distinct advantages and limitations contingent upon the specific conditions and requisites of the business environment in question. The author asserts that there exists no singular optimal model universally applicable to all scenarios, underscoring the imperative for flexible integration and adaptation of varied approaches. Illustratively, this may involve the amalgamation of Porter's Five Forces model with SWOT analysis, accounting for both internal and external factors, or the augmentation of the McKinsey 7S Model with external analyses, such as PESTEL analysis. The conclusions drawn in the article underscore that the achievement of success in strategic decision-making within the contemporary dynamic and unpredictable business environment hinges on organizations' capacity for flexibility, adaptability, and innovation. The escalating complexity and rapid pace of change necessitate companies to formulate comprehensive strategies that encompass various aspects and approaches for the development of effective solutions.
ASSESSMENT OF THE IMPACT OF GLOBALIZATION ON THE REGIONAL DEVELOPMENT OF INNOVATION CLUSTER
Authors: HERMAN LIUDMYLA , FEDIRKO OLEKSANDR , KOSTYK YEVHENII , SHKODA MARIANA , SOKHAN INNA
Published: February 2024

The article delves into the complex dynamics of innovation clusters moving through the complex landscape of global trends and challenges inherent in the comprehensive process of globalization. The multifaceted influence of global factors on the evolution of innovation clusters within the framework of the modern economic situation is also meticulously studied. In the course of the analysis, a special emphasis has been placed on a detailed examination of the challenges arising as a result of the current processes of globalization and the rapid development of innovative technologies. The present research identifies the key role played by innovation clusters as integral components of regional development and essential contributors to the tangled web of global production chains. One of the most important findings is the reconciliation of local and global interests in the circumstances surrounding the establishment and operation of innovation clusters. It has also been determined that globalization is a stimulus for innovative development and the emergence of new challenges to ensure the sustainable competitiveness of regional clusters in the global economic environment has been substantiated. It is noted that countries where innovation clusters demonstrate successful integration into global production chains actively use the advantages of globalization to develop their regional innovation systems. The primary purpose of the analysis was to determine the factors contributing to the successful integration of clusters into global processes. These factors include effective cluster management, the development of a flexible innovation strategy, and the ability to adapt to changes in the global economic environment. The role of innovation management in the context of globalization is considered separately, in particular, the need for constant monitoring and analysis of global innovation trends.
LIABILITY FOR VIOLATION OF FAMILY RIGHTS AND OBLIGATIONS UNDER UKRAINIAN AND THE EU LEGISLATION
Authors: VATRAS VOLODYMYR , HAVRIK ROMAN , STEFANCHUK MYKOLA , SABLUK SERHII , BONDARENKO-ZELINSKA NADIIA
Published: February 2024

The issue of liability for violation of family rights and obligations under the laws of Ukraine and the EU has always been of interest to domestic and foreign scholars. The main objective of our state in the field of family law is to harmonize the legislation with the norms of the European Union. The observance of human rights is a fundamental provision in international law and in Ukraine. After all, the rights of children, women, and parents in the family should be the highest legal and social value and they should be protected by the state in every state governed by the rule of law. The norms of international legislation enshrined in the fundamental documents must be observed in the states that have ratified them. The purpose of the research is to theoretically analyze the liability for violation of family rights and obligations under the legislation of Ukraine and the EU, to study the legal sources and to search for ways to solve the main current issues by studying domestic and international legislation and analyzing the scholars’ works. The regulatory framework governing the consequences of violating family rights and obligations is the subject of discussion.
Traversing Time: Dialectical Temporal Gestures in the Blended Genre of the Essay Manifesto
Authors: Junker Carsten
Published: February 2024

The article confronts genre theory with considerations of temporality. Starting from the assumption that the genres of essay and manifesto lend themselves to divergent constructions of time, it interrogates the artificiality of generic demarcations and highlights formalisations of time in the blended genre of the essay manifesto. Considering select representative texts, the article brings into view manifold dynamics that might otherwise be missed, especially with regard to temporality. Rather than assuming contrastive constructions of time on a spectrum of tension between the poles of duration (length of time and permanence) and momentariness (brevity and transitoriness), the article introduces the concept of dialectical gestures of time in the sense of two interrelated, mutually constitutive notions of momentary duration and enduring momentariness. As is shown, foregrounding dialectical temporal gestures in the essay manifesto highlights critical functional aspects of this form, including polemical disruption and explorative reflection.
Family Experiences in Caring for Covid-19 Positive at Home: Phenomenology Study
Authors: Fradianto Ikbal , Mita Mita , Yulanda Nita Arisanti , Rahmawati Nadia , Putri Triyana Harlia , Andriyanto Arief
Published: February 2024

Aims: Covid-19, a global problem since 2019, has significantly increased in Indonesia since early 2020. Government policies restrict patients from outside activities, making home care a unique experience. This study aims to understand families' experiences in caring for positive Covid-19 patients.
Methods: The method used is qualitative with a phenomenological study approach. There were 12 participants in this study with the criteria of accompanying patients who experienced Covid-19 <1 year and these companions cared for patients at home. The sampling technique used was purposive sampling, with in-depth interviews of 30-45 minutes and recorded and recorded. The data analysis technique used is the collaizi method.
Results: The results of the study obtained six themes, namely understanding Covid-19 Disease, Information Sources for Covid-19 Treatment, Treatment Considerations, Psychological Burden, Difficulties in Home Care, and Social Support.
Conclusions: This study found six themes related to family experience in caring for Covid-19 patients, so that the role of the family and social community is very important in caring for Covid-19 patients in dealing with changing conditions and situations.
The Influence of Dhikr on Anxiety in Acute Coronary Syndrome (ACS) Patients at Dr. Chasbullah Abdulmadjid Hospital, Bekasi City
Authors: Sulistiyowati Heppy , Jumaiyah Wati , Purnamawati Dewi , Sofiani Yani , Susanto Budi , Prima Ashar , Hamdah Hamdah
Published: February 2024

Aims: This study was to determine the effect of dhikr on anxiety in ACS patients at Dr. Chasbullah Abdulmadjid General Hospital, Bekasi City.
Methods: The research method used pre- and post-quasy experiments in the control group and the intervention group. This study used the HARS questionnaire and family support for 76 respondents.
Result: Data analysis using multiple logistic regression tests The results showed that the proportion in the control group with mild-moderate anxiety was 31.6% and severe anxiety was 18.4%; the proportion in the intervention group with mild-moderate anxiety was 46.1% and severe anxiety was 3.9%. Dhikr (p = 0.006) and history of heart disease (p = 0.023) significantly influence anxiety after being controlled by age (p = 0.244) (p = 0.001 omnimbus). The dominant factor that influences anxiety is dhikr (OR 10.674). 
Conclusions : Dhikr is an act of remembering Allah that can be used to reduce anxiety in SKA patients. This can be done independently by reading istigfar, tasbih, hauqalah, and takbir for 15 minutes in the morning and evening. Therefore, nursing services using dhikr as an effort to reduce anxiety in ACS patients.
Effect of Isometric Handgrip Exercise on Sleep Quality of Hypertension Patients in the Elderly
Authors: Lucya Vita , Pratiwi Gilang Dwi , Anggie Novita
Published: February 2024

Aims: The study aimed to knowing the effect of isometric handgrip exercise on the quality of sleep of hypertension patients in the elderly.
Methods: The study was Quasi Experiment research with one group pretest-posttest design. The study population was purposive sampling and obtained a total of 30 respondents.  This research was conducted at the Sukawarna Health Center Work Area, Bandung City. The instrument used was PSQI (Pittsburgh Sleep Quality Index).
Results: There was an effect ofisometric handgrip exercise on the quality of sleep of hypertension patients in the elderly (p-value = 0,000).
Conclusion: Isometric handgrip exercise is a non-pharmacological therapy that can be used to improve quality of sleep of hypertension patients in the elderly.
Development of Fast Alcohol Screening Test Implementation and Electronic Nursing Interventions for Adolescents with Alcohol Abuse: A Literature Review
Authors: Triaswati Rusmai , Hariyati Rr. Tutik Sri , Daulima Novy Helena Catharina
Published: February 2024

Aims: This literature review aims to theoretically analyze the rationale for developing this electronic application to cover all aspects of adolescent mental health life and as a promotive and preventive tool for adolescents with alcohol abusers.
Methods: The literature review method was carried out on ten articles which were obtained from five databases namely PUBMED, Google Scholar, ClinicalKey Nursing, ProQuest, Science Direct. The keywords for article search were "FAST (Fast alcohol screening test)", "electronic-based nursing care", "alcohol abuse", "adolescent". The criteria for articles considered included articles available in English and Indonesian and published between 2017 and 2023.
Results: This review shows that the use of FAST and electronic-based nursing care can improve the quality of nursing care.
Conclusion: The utilization of technology in the screening test process and electronic based nursing care in nursing care is one of the alternative problem solving and especially can improve the quality of nursing care.
A heuristic approach of modelling developing countries' construction sector uncertainties to improve the building environment
Authors: Pettang Nana Ursula Joyce Merveilles , Fandjio Yonzou Cédric Cabral , Mbiada Mbiada Patrick Joël , Abanda Fonbeyin Henry , Pettang Chrispin
Published: February 2024

The building environment is predominated almost everywhere in developing countries by fuzzy and unconventional mechanisms, which forms the so-called “informal sector.” The implementation of projects by the owners themselves, small and medium-sized enterprises, in this environment requires severe cost control and time delivery. The construction process in such a complex area is subject to labour fluctuations, productivity variability, difficulties in logistic supply, poor management, use of unsuitable methods, instability of financial means, and therefore delays in the payment of accounts by the contracting authorities. The factors mentioned above are source of major discrepancies between the forecast costs, quality, and deadlines and those obtained at the end of the project. This explains the losses in the execution phase and the prejudices suffered by the main actors in the unconventional construction industry at all levels. By comparing this specific construction sector with the standards, specific uncertainties emerge at several levels of understanding and execution, which, for each task, are the variabilities in quantity, performance, and qualification of workers; the quality and cost fluctuations among supplying networks of materials; the availability and/or inadequacy of equipment used; and the improvised managerial and financial mechanisms. This study, based on matrix modelling of the components of the construction site, leads to implementation of a heuristic approach for assessing those construction costs and delays uncertainties. We proposed analytic formulations of uncertainties that are computed every iteration of possible scenarios. By adapting and applying an iterative (TABU Search), a heuristic algorithm for minimising costs and lead times, it is possible to combine virtually all the possible choices for the different variables in order to anticipate the impact and guide the decision-maker towards the scenario with the least uncertainty and a good reliability of occurrence. Considering the complex parameters of this site of “informal” construction, the model aims to enable stakeholders in the construction sector to incorporate uncertainties into their forecasts before taking decisions not only to reduce or decrease financial losses but also to increase their credibility and ultimately improve this common practice of sustainable construction.
A nomogram for predicting left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation patients using hemodynamic parameters from transthoracic echocardiography
Authors: Zeng Decai , Zhang Xiaofeng , Chang Shuai , Zhong Yanfen , Cai Yongzhi , Huang Tongtong , Wu Ji
Published: February 2024

Background

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with a high risk of stroke. This study was designed to investigate the relationship between hemodynamic parameters and left atrial thrombus/spontaneous echo contrast (LAT/SEC) in non-valvular atrial fibrillation (NVAF) patients and establish a predictive nomogram that integrates hemodynamic parameters with clinical predictors to predict the risk of LAT/SEC.

Methods

From January 2019 to September 2022, a total of 354 consecutive patients with NVAF were enrolled in this cross-sectional study at the First Affiliated Hospital of Guangxi Medical University. To identify the optimal predictive features, we employed least absolute shrinkage and selection operator (LASSO) regression. A multivariate logistic regression model was subsequently constructed, and the results were visualized with a nomogram. We evaluated the model's performance using discrimination, calibration, and the concordance index (C-index).

Results

We observed a 38.7% incidence of SEC/TH in NVAF patients. Independent influencing factors of LAT/SEC were identified through LASSO and multivariate logistic regression. Finally, four indicators were included, namely, previous stroke/transient ischaemic attack (OR = 4.25, 95% CI = 1.57–12.23, P = 0.006), left atrial volume index (LAVI) (OR = 1.04, 95% CI = 1.01–1.06, P = 0.001), S/D ratio (OR = 0.27, 95% CI = 0.11–0.59, P = 0.002), and left atrial acceleration factor (OR = 4.95, 95% CI = 2.05–12.79, P = 0.001). The nomogram, which incorporated these four influencing factors, demonstrated excellent predictive ability. The training set had a C-index of 0.878, while the validation set had a C-index of 0.872. Additionally, the calibration curve demonstrated great consistency between the predicted probabilities and the observed outcomes, and the decision curve analysis confirmed the important clinical advantage of the model for patients with NVAF.

Conclusion

Our findings indicate that an enlarged left atrium and abnormal hemodynamic parameters in the left atrial and pulmonary veins are linked to a greater risk of LAT/SEC. Previous stroke/transient ischaemic attack, LAVI, the S/D ratio, and left atrial acceleration factor were independently associated with LAT/SEC in NVAF patients. With the incorporation of these four variables, the developed nomogram effectively predicts the risk of LAT/SEC and outperforms the CHA2DS2-VASc score.
Machine learning in toxicological sciences: opportunities for assessing drug toxicity
Authors: Tonoyan Lusine , Siraki Arno G.
Published: February 2024

Machine learning (ML) in toxicological sciences is growing exponentially, which presents unprecedented opportunities and brings up important considerations for using ML in this field. This review discusses supervised, unsupervised, and reinforcement learning and their applications to toxicology. The application of the scientific method is central to the development of a ML model. These steps involve defining the ML problem, constructing the dataset, transforming the data and feature selection, choosing and training a ML model, validation, and prediction. The need for rigorous models is becoming more of a requirement due to the vast number of chemicals and their interaction with biota. Large datasets make this task possible, though selecting databases with overlapping chemical spaces, amongst other things, is an important consideration. Predicting toxicity through machine learning can have significant societal impacts, including enhancements in assessing risks, determining clinical toxicities, evaluating carcinogenic properties, and detecting harmful side effects of medications. We provide a concise overview of the current state of this topic, focusing on the potential benefits and challenges related to the availability of extensive datasets, the methodologies for analyzing these datasets, and the ethical implications involved in applying such models.
Comparative prognosis and risk assessment in gallbladder neuroendocrine neoplasms versus adenocarcinomas
Authors: Zhao Zhi-Hao , Huang Yu , Jiang Chao , Lv Guo-Yue , Wang Meng
Published: February 2024

Background

Gallbladder neuroendocrine neoplasms (GB-NENs) are a rare malignant disease, with most cases diagnosed at advanced stages, often resulting in poor prognosis. However, studies regarding the prognosis of this condition and its comparison with gallbladder adenocarcinomas (GB-ADCs) have yet to yield convincing conclusions.

Methods

We extracted cases of GB-NENs and GB-ADCs from the Surveillance, Epidemiology, and End Results (SEER) database in the United States. Firstly, we corrected differences in clinical characteristics between the two groups using propensity score matching (PSM). Subsequently, we visualized and compared the survival outcomes of the two groups using the Kaplan-Meier method. Next, we employed the least absolute shrinkage and selection operator (LASSO) regression and Cox regression to identify prognostic factors for GB-NENs and constructed two nomograms for predicting prognosis. These nomograms were validated with an internal validation dataset from the SEER database and an external validation dataset from a hospital. Finally, we categorized patients into high-risk and low-risk groups based on their overall survival (OS) scores.

Results

A total of 7,105 patients were enrolled in the study, comprising 287 GB-NENs patients and, 6,818 GB-ADCs patients. There were substantial differences in clinical characteristics between patients, and GB-NENs exhibited a significantly better prognosis. Even after balancing these differences using PSM, the superior prognosis of GB-NENs remained evident. Independent prognostic factors selected through LASSO and Cox regression were age, histology type, first primary malignancy, tumor size, and surgery. Two nomograms for prognosis were developed based on these factors, and their performance was verified from three perspectives: discrimination, calibration, and clinical applicability using training, internal validation, and external validation datasets, all of which exhibited excellent validation results. Using a cutoff value of 166.5 for the OS nomogram score, patient mortality risk can be identified effectively.

Conclusion

Patients with GB-NENs have a better overall prognosis compared to those with GB-ADCs. Nomograms for GB-NENs prognosis have been effectively established and validated, making them a valuable tool for assessing the risk of mortality in clinical practice.