bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Review of Mycotoxin Biodegradation and Bioadsorption: Microorganisms, Mechanisms, and Main Important Applications
Authors: Ndiaye Seyni , Zhang Minhui , Fall Mouhamed , Ayessou Nicolas M. , Zhang Qi , Li Peiwu
Published: October 2022

Mycotoxins are secondary metabolites produced by fungi. Food/feed contamination by mycotoxins is a great threat to food safety. The contamination can occur along the food chain and can cause many diseases in humans and animals, and it also can cause economic losses. Many detoxification methods, including physical, chemical, and biological techniques, have been established to eliminate mycotoxins in food/feed. The biological method, with mycotoxin detoxification by microorganisms, is reliable, efficient, less costly, and easy to use compared with physical and chemical ones. However, it is important to discover the metabolite’s toxicity resulting from mycotoxin biodegradation. These compounds can be less or more toxic than the parent. On the other hand, mechanisms involved in a mycotoxin’s biological control remain still unclear. Mostly, there is little information about the method used by microorganisms to control mycotoxins. Therefore, this article presents an overview of the most toxic mycotoxins and the different microorganisms that have a mycotoxin detoxification ability. At the same time, different screening methods for degradation compound elucidation are given. In addition, the review summarizes mechanisms of mycotoxin biodegradation and gives some applications.
From Clusters to Proto-Clusters: The Infrared Perspective on Environmental Galaxy Evolution
Authors: Alberts Stacey , Noble Allison
Published: October 2022

Environment is one of the primary drivers of galaxy evolution; via multiple mechanisms, it can control the critical process of transforming galaxies from star forming to quiescent, commonly termed “quenching”. Despite its importance, however, we still do not have a clear view of how environmentally-driven quenching proceeds even in the most extreme environments: galaxy clusters and their progenitor proto-clusters. Recent advances in infrared capabilities have enabled transformative progress not only in the identification of these structures but in detailed analyses of quiescence, obscured star formation, and molecular gas in (proto-)cluster galaxies across cosmic time. In this review, we will discuss the current state of the literature regarding the quenching of galaxies in (proto-)clusters from the observational, infrared perspective. Our improved understanding of environmental galaxy evolution comes from unique observables across the distinct regimes of the near-, mid-, and far-infrared, crucial in the push to high redshift where massive galaxy growth is dominated by highly extinct, infrared-bright galaxies.
Helium Abundance Decrease in ICMEs in 23–24 Solar Cycles
Authors: Khokhlachev Alexander A. , Yermolaev Yuri I. , Lodkina Irina G. , Riazantseva Maria O. , Rakhmanova Liudmila S.
Published: October 2022

Based on the OMNI database, the influence of the solar activity decrease in solar cycles (SCs) 23–24 on the behavior of the relative helium ions abundance Nα/Np inside interplanetary coronal mass ejections (ICMEs) is investigated. The dependences of the helium abundance on the plasma and interplanetary magnetic field parameters in the epoch of high solar activity (SCs 21–22) and the epoch of low activity (SCs 23–24) are compared. It is shown that Nα/Np significantly decreased in SCs 23–24 compared to SCs 21–22. The general trends of the dependences have not changed with the change of epoch, but the helium abundance dependences on some parameters (for example, the magnitude of the interplanetary magnetic field) have become weaker in the epoch of low activity than they were in the epoch of high activity. In addition, the dependence of the helium abundance on the distance from spacecraft to the ICME axis was revealed; the clearest dependence is observed in magnetic clouds. The Nα/Np maximum is measured at the minimum distance, which confirms the hypothesis of the existence of a helium-enriched electric current inside an ICME.
Preparation of Monoclonal Antibodies against the Viral p54 Protein and a Blocking ELISA for Detection of the Antibody against African Swine Fever Virus
Authors: Gao Yanni , Xia Tingting , Bai Juan , Zhang Lujie , Zheng Haixue , Jiang Ping
Published: October 2022

African swine fever virus (ASFV) causes a highly contagious viral disease in domestic and wild pigs, leading to serious economic losses. As there are no vaccines or drugs available, early accurate diagnosis and eradiation of infected animals are the most important measures for ASFV prevention and control. Therefore, improvement of available diagnostic assays and development of novel effective techniques are required. This study is devoted to generating a new detection platform of blocking monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA) against ASFV p54 protein. Seven monoclonal antibodies against recombinant p54 protein were produced and four epitopes were identified. Three blocking ELISAs were developed with 6A5 and 6F9 mAbs labeled with HRP, respectively, of which the 6A5/6F9-based blocking ELISA displayed the best detection performance, with an AUC of 0.986, sensitivity of 98.36% and specificity of 92.36% in ROC analysis. Moreover, it has an excellent agreement at 96.59% (198/205) when compared to the commercial blocking ELISA (kappa value = 0.920). The method also has high repeatability, with CV <10%, and no cross reaction with the serum antibodies against PRV, PRRSV, CSFV, PCV2 or SVA. This indicates that the 6A5/6F9-based blocking ELISA has high accuracy with good sensitivity and specificity, suitable for viral detection, field surveillance and epidemiological studies.
Effects of COVID-19 and Social Distancing on Rhinovirus Infections and Asthma Exacerbations
Authors: Kreger Jordan E. , Hershenson Marc B.
Published: October 2022

Since their discovery in the 1950s, rhinoviruses (RVs) have been recognized as a major causative agent of the “common cold” and cold-like illnesses, accounting for more than 50% of upper respiratory tract infections. However, more than that, respiratory viral infections are responsible for approximately 50% of asthma exacerbations in adults and 80% in children. In addition to causing exacerbations of asthma, COPD and other chronic lung diseases, RVs have also been implicated in the pathogenesis of lower respiratory tract infections including bronchiolitis and community acquired pneumonia. Finally, early life respiratory viral infections with RV have been associated with asthma development in children. Due to the vast genetic diversity of RVs (approximately 160 known serotypes), recurrent infection is common. RV infections are generally acquired in the community with transmission occurring via inhalation of aerosols, respiratory droplets or fomites. Following the outbreak of coronavirus disease 2019 (COVID-19), exposure to RV and other respiratory viruses was significantly reduced due to social-distancing, restrictions on social gatherings, and increased hygiene protocols. In the present review, we summarize the impact of COVID-19 preventative measures on the incidence of RV infection and its sequelae.
First Report of Wenzhou sobemo-like virus 4 in Aedes albopictus (Diptera: Culicidae) in Latin America
Authors: Andrade Pâmela , Valença Ian , Heinisch Marta , Rocha Esmenia , Fernandes Lícia , Faria Nuno , Sabino Ester , Lima-Camara Tamara
Published: October 2022

Insect-specific viruses (ISVs) are viruses that replicate exclusively in arthropod cells. Many ISVs have been studied in mosquitoes as many of them act as vectors for human etiological agents, such as arboviruses. Aedes (Stegomyia) albopictus is an important potential vector of several arboviruses in Brazil, such as dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV). The development of next-generation sequencing metagenomics has enabled the discovery and characterization of new ISVs. Ae. albopictus eggs were collected using oviposition traps placed in two urban parks in the city of São Paulo, Brazil. The Aedes albopictus females were divided into pools and the genetic material was extracted and processed for sequencing by metagenomics. Complete genomes of ISV Wenzhou sobemo-like virus 4 (WSLV4) were obtained in three of the four pools tested. This is the first detection of ISV WSLV4 in Ae. albopictus females in Latin America. Further studies on ISVs in Ae. albopictus are needed to better understand the role of this species in the dynamics of arbovirus transmission in the Americas.
COVID-19 Vaccine Hesitancy among Pregnant Women Attending Antenatal Clinics in Pakistan: A Multicentric, Prospective, Survey-Based Study
Authors: Mustafa Zia Ul , Bashir Shazma , Shahid Arfah , Raees Iqra , Salman Muhammad , Merchant Hamid A. , Aldeyab Mamoon A. , Kow Chia Siang , Hasan Syed Shahzad
Published: October 2022

This study aimed to assess the vaccination status and factors contributing to vaccine hesitancy among pregnant women in the largest province of Pakistan. A multicentric, prospective, survey-based study using an interviewer-administered tool was conducted among pregnant women attending antenatal clinics between 1 December 2021 through 30 January 2022 across seven hospitals in Pakistan. The healthcare professionals providing care at the participating hospitals administered the survey. Four hundred and five pregnant women fully consented and completed the study. The majority of the study participants (70.6%, n = 286) were aged between 25 and 34 and had a previous successful pregnancy history. More than half of the study participants (56.0%, n = 227) did not receive COVID-19 vaccination at the time of data collection despite their family members (93.9%, n = 372) had already received at least one dose of COVID-19 vaccine. Among those who received COVID-19 vaccination (n = 173), vaccine efficacy, protection for the foetus, and risk of COVID-19-associated hospitalisation were the main driving factors for vaccine hesitancy. The majority of the unvaccinated women (77.8%, n = 182) had no intention of receiving the vaccine. However, more than two-thirds (85.7%, n = 342) consulted the doctor about COVID-19 vaccines, and most were recommended to receive COVID-19 vaccines by the doctors (80.7%, n = 280). Women were significantly more likely to be vaccinated if they had employment (odds ratio [OR] 4.47, 95% confidence interval [CI]: 2.31–8.64) compared with their counterparts who were homemakers, consulted their doctors (OR 0.12, 95% CI: 0.04–0.35), and if they did not have pregnancy-related issues (OR 6.02, 95% CI: 2.36–15.33). In this study, vaccine hesitancy was prevalent, and vaccine uptake was low among pregnant women. Education and employment did impact COVID vaccination uptake, emphasising the need for more targeted efforts to enhance the trust in vaccines.
Comprehensive Analysis of Ubiquitome Changes in Nicotiana benthamiana after Rice Stripe Virus Infection
Authors: Liu Yu , Li Chenyang , Wang Yaqin , Xu Yi , Wu Jianxiang , Zhou Xueping
Published: October 2022

Rice stripe virus (RSV) is one of the most devastating viruses affecting rice production. During virus infection, ubiquitination plays an important role in the dynamic regulation of host defenses. We combined the ubiquitomics approach with the label-free quantitation proteomics approach to investigate potential ubiquitination status changes of Nicotiana benthamiana infected with RSV. Bioinformatics analyses were performed to elucidate potential associations between proteins with differentially ubiquitinated sites (DUSs) and various cellular components/pathways during virus infection. In total, 399 DUSs in 313 proteins were identified and quantified, among them 244 ubiquitinated lysine (Kub) sites in 186 proteins were up-regulated and 155 Kub sites in 127 proteins were down-regulated at 10 days after RSV infection. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses indicated that proteins with up-regulated Kub sites were significantly enriched in the ribosome. Silencing of 3-isopropylmalate dehydratase large subunit through virus-induced gene silencing delayed RSV infection, while silencing of mRNA-decapping enzyme-like protein promoted RSV symptom in the late stage of infection. Moreover, ubiquitination was observed in all seven RSV-encoded proteins. Our study supplied the comprehensive analysis of the ubiquitination changes in N. benthamiana after RSV infection, which is helpful for understanding RSV pathogenesis and RSV-host interactions.
Isolation, Characterization, and Genome Analysis of a Novel Bacteriophage, Escherichia Phage vB_EcoM-4HA13, Representing a New Phage Genus in the Novel Phage Family Chaseviridae
Authors: Lin Janet T. , Kirst Sarah , Cucić Stevan , Klem Alexandra , She Yi-Min , Kropinski Andrew M. , Anany Hany
Published: October 2022

Shiga toxin-producing Escherichia coli (STEC) is one of the leading causes of foodborne illnesses in North America and can lead to severe symptoms, with increased fatality risk for young children. While E. coli O157:H7 remains the dominant STEC serotype associated with foodborne outbreaks, there has been an increasing number of non-O157 STEC outbreaks in recent years. For the food industry, lytic bacteriophages offer an organic, self-limiting alternative to pathogen reduction—one that could replace or reduce the use of chemical and physical food processing methods. From EHEC-enriched sewage, we isolated a novel bacteriophage, vB_EcoM-4HA13 (4HA13). Phenotypic characterizations revealed 4HA13 to possess a myoviral morphotype, with a high specificity to non-motile O111 serotype, and a long latent period (90 min). Through genomic analyses, this 52,401-bp dsDNA phage was found to contain 81 CDS, but no detectable presence of antibiotic resistance, integrase, or virulence genes. A BLASTn search for each of the identified 81 CDS yielded homologues with low levels of similarity. Comparison of RNA polymerase and terminase large subunit amino acid sequences led to the proposal and acceptance of a new bacteriophage family, Chaseviridae, with 4HA13 representing a new species and genus. The discovery of this phage has broadened our current knowledge of bacteriophage diversity.
Genomic Characterisation of Canis Familiaris Papillomavirus Type 24, a Novel Papillomavirus Associated with Extensive Pigmented Plaque Formation in a Pug Dog
Authors: Munday John S. , Gedye Kristene , Knox Matthew A. , Ravens Philippa , Lin Xiaoxiao
Published: October 2022

Numerous large dark plaques developed over the ventrum, legs and head of a 9-year-old pug dog over a 4-year-period. Histology confirmed a diagnosis of viral pigmented plaque and a short section of a novel papillomavirus (PV) type was amplified using consensus PCR primers. Taking advantage of the circular nature of PV DNA, ‘outward facing’ PCR primers allowed amplification of the full sequence. As this is the 24th PV known to infect dogs, the novel PV was designated canine papillomavirus (CPV) type 24. The CPV24 genome contained putative coding regions for 5 early proteins and 2 late ones. The CPV24 open reading frame L1 showed the highest (78.2%) similarity to CPV4 and phylogenetic analysis showed that CPV24 clustered with CPV4 and CPV16 suggesting CPV24 is the third species 2 Chipapillomavirus type identified in dogs. This is the third report of extensive pigmented plaques covering a high proportion of the skin. Both previous cases were caused CPV4 and, considering the high genetic similarity between CPV4 and CP24, infection by these CPV types may predispose to more severe clinical disease. In addition, as plaques caused by CPV16 appear more likely to progress to neoplasia, the detection of a species 2 Chipapillomavirus within a pigmented plaque may indicate the potential for more severe disease.
Plant Molecular Pharming and Plant-Derived Compounds towards Generation of Vaccines and Therapeutics against Coronaviruses
Authors: Venkataraman Srividhya
Published: October 2022

The current century has witnessed infections of pandemic proportions caused by Coronaviruses (CoV) including severe acute respiratory syndrome-related CoV (SARS-CoV), Middle East respiratory syndrome-related CoV (MERS-CoV) and the recently identified SARS-CoV2. Significantly, the SARS-CoV2 outbreak, declared a pandemic in early 2020, has wreaked devastation and imposed intense pressure on medical establishments world-wide in a short time period by spreading at a rapid pace, resulting in high morbidity and mortality. Therefore, there is a compelling need to combat and contain the CoV infections. The current review addresses the unique features of the molecular virology of major Coronaviruses that may be tractable towards antiviral targeting and design of novel preventative and therapeutic intervention strategies. Plant-derived vaccines, in particular oral vaccines, afford safer, effectual and low-cost avenues to develop antivirals and fast response vaccines, requiring minimal infrastructure and trained personnel for vaccine administration in developing countries. This review article discusses recent developments in the generation of plant-based vaccines, therapeutic/drug molecules, monoclonal antibodies and phytochemicals to preclude and combat infections caused by SARS-CoV, MERS-CoV and SARS-CoV-2 viruses. Efficacious plant-derived antivirals could contribute significantly to combating emerging and re-emerging pathogenic CoV infections and help stem the tide of any future pandemics.
Isotopic Evidence for Anaerobic Oxidation of Methane in the Freshwater Sediments of Reservoirs: The Impact of Selected Environmental Factors
Authors: Gruca-Rokosz Renata , Szal Dorota
Published: October 2022

This paper presents the results of research conducted in 2018–2019 on the anaerobic oxidation of methane (AOM) in reservoir sediments. Located in SE Poland, Maziarnia, Nielisz and Rzeszów Reservoirs were selected for the purposes of the research. Rates of AOM were determined via 50-day incubation of sediment from the 0–5, 5–10 and 10–15 cm layers, to which a 13CH4 isotope tracer was added. The sediments had been collected from a single station at each reservoir in places that had earlier reported high levels of emission of CH4 to the atmosphere. Results demonstrate ongoing AOM processes in the kinds of freshwater ecosystem represented by reservoirs, further implying the existence of an important sink for CH4. More specifically, however, AOM rates were found to differ among both the reservoirs, and the layers of sediment, studied. Preliminary analysis of selected environmental factors capable of affecting AOM failed to suggest the availability of electron acceptors (NO3−, SO42−, Fe3+) as key controlling factors. Important factors also proved to be sediment pH, the quality of organic matter (especially the content of organic electron acceptors), the salinity of pore water, and—primarily—the presence of the microorganisms actually responsible for AOM. The results here are important, given the low level of knowledge of AOM process in reservoirs. They therefore help supply key information on the functioning of these ecosystems and the role in global climate change they play.
Mechanism and Reactive Species in a Fountain-Strip DBD Plasma for Degrading Perfluorooctanoic Acid (PFOA)
Authors: Cheng Jiushan , Fan Yangyang , Pei Xueyun , Tian Di , Liu Zhongwei , Wei Zachary Z. , Ji Hai-feng , Chen Qiang
Published: October 2022

Perfluorooctanoic acid (PFOA) is an artificially synthesized perfluorinated chemical widely used in industries. It is often released into the environment without treatment, which causes pollution in groundwater. Recently, we have reported a rapid and efficient removal of PFOA in aqueous solution by using a fountain-strip dielectric barrier discharge reactor (SF-DBD). This design allows for the gaseous–liquid interaction to happen in a large space at atmospheric pressure, so it is a promising method to efficiently remove PFOA from water. Recently, we reported the effects of the process parameters, including power mode, pulse time, sinusoidal wave discharge, the discharge gas, initial concentration, pH, conductivity, and positive and negative discharges, on the efficiency of this method for PFOA degradation. Understanding the reaction mechanism is key to further improve the efficiency of the system. In this work, we reported the decomposition mechanism of the SF-DBD for PFOA degradation. The mass spectrum (MS) showed that PFOA was degraded to perfluoroheptanoic acid, perfluorohexanoic acid, perfluoropentanoic acid, perfluorobutanoic acid, perfluoropropionic acid, and trifluoroacetic acid after the plasma treatment. The optical emission spectroscope (OES) and the radical scavenger experiments indicated that the excited argon atoms and hydroxyl radicals played a major role in PFOA degradation, while the contributions from the solvated electrons (e−aq), superoxide anion radical (·O2−), and singlet oxygen (1O2) were negligible in initiating the cleavage reaction.
Combined Transcriptome and Metabolome Analysis of a New Species of Microalgae from the Tibetan Plateau and Its Response to Sewage Treatment
Authors: Wang Jinhu , Zhang Qiangying , Chen Junyu , Zhou Jinna , Li Jing , Wei Yanli , Regmi Balmukunda , Bu Duo
Published: October 2022

Microalgae are pivotal in maintaining water quality in the lakes and rivers of Qinghai-Tibet plateau. The optimum sewage treatment conditions for Desmodesmus sp. Are, temperature: 20–25 °C, light intensity: 3000–8000 lx, and pH: 7.0–7.5, identified based on orthogonal experiments. The maximum removal rate of total nitrogen, total phosphorus, and chemical oxygen demand was more than 95% in the actual sewage treatment. The sewage treatment capacity of Desmodesmus sp. From plateau is higher than that from plains under the same treatment conditions. To identify the differentially expressed genes and metabolites in Desmodesmus sp. In response to sewage treatment, a combination of metabolomics and transcriptomics was employed to the microalgae with and without sewage treatment. The results showed that the oxidative phosphorylation, photosynthesis, and propanoate metabolism pathways were the most significantly enriched pathways in sewage treatment. Furthermore, the metabolism of adenosine diphosphate, 2-oxobutanoate, and succinate were significantly upregulated, downregulated, and both upregulated and downregulated, respectively, as shown by the combined transcriptome and metabolome analysis. Additionally, we found that sewage treatment could also induce numerous changes in the primary metabolism, such as carbohydrate, fatty acid biosynthesis, and amino acid metabolism when compared with control. Overall, our results should improve fundamental knowledge of molecular responses to Desmodesmus sp. in sewage treatment and contribute to the design of strategies in microalgae response to sewage treatment.
EFEITO DO EXTRATO DE GENGIBRE (ZINGIBER OFFICINALE ROSCOE) EM PACIENTES COM NÁUSEAS E VÔMITOS NO TRATAMENTO QUIMIOTERÁPICO
Authors: Crescêncio William Gutemberg Diógenes , Castro Isis Prado Meirelles de , Morbeck Natália Belo Moreira , Panontin Juliane Farinelli
Published: October 2022

O gengibre é internacionalmente usado e comercializado para o uso na indústria de alimentos, química e farmacêutica, muito reconhecido pelo seu uso medicinal, auxilia na diminuição de alguns sintomas e patologias. Dentre as inúmeras propriedades desta raiz que são estudadas pelos cientistas estão a atividades antieméticas e antináuseas, antimutagênica, antiulcera, hipoglicemica, antibacteriana, entre outras. Este trabalho teve o objetivo de realizar uma revisão da literatura que aborda as propriedades terapêuticas e potenciais da aplicação do gengibre como complemento no tratamento de vômitos e náuseas induzidas por quimioterapia. Para isso, foi feito uma busca de material bibliográfico, em bases de dados como o SCIELO, EBSCO, Google Acadêmico e PubMed., utilizando os termos: gengibre, náusea, vômito, quimioterápico, manipulação ou equivalentes. Os critérios de inclusão foram os artigos publicados na íntegra sobre o objeto de estudo, no período de 2000 a 2020. A maioria dos resultados de pesquisas mostram que o extrato dessa planta é uma estratégia profilática efetiva para reduzir os sintomas decorrentes do tratamento quimioterápico. Muitos estudos conseguem atestar uma diminuição no desconforto gástricos dos pacientes. Mesmo que os resultados direcionem para o uso do gengibre como antiemético para pacientes oncológicos, de forma que possam suportar todo o tratamento, mantendo uma melhor qualidade de vida, ainda são necessárias novas investigações, de forma que se estabeleça um protocolo seguro quanto a posologia, administração e eficácia dessa estratégia.
SOCIAL INTELLIGENCE IN THE STRUCTURE OF PROFESSIONALLY IMPORTANT QUALITIES OF A PSYCHOLOGIST
Authors: Yanovska T.
Published: October 2022

peculiarities of the formation of social intelligence in psychologists. The definition of the essence of the concept of "social intelligence" in psychology is analyzed. Social intelligence is seen as a separate type of intelligence that is practical and different from abstract intelligence. It is a stable, based on the specifics of mental processes, affective response and social experience, the ability to understand themselves, other people, their relationships and predict interpersonal events. Since social intelligence is considered a multidimensional, complex structure, the following aspects are distinguished: communicative-personal potential, characteristics of self-awareness, social perception and social thinking, ability to understand and model social phenomena, understanding of people and motives, mental and physical endurance, activity. Attention is drawn to the fact that this is a type of intelligence that provides intelligent human behavior in social interaction based on the integration of the results of social cognition, personal characteristics and self-regulation of social behavior. The problem of determining the requirements for a professional psychologist is studied, the peculiarities of the professional activity of a specialist are analyzed and social intelligence in the structure of professionally important qualities of a psychologist is substantiated. It is emphasized that the problem of development of social intelligence in practical psychologists is currently very relevant, because their professional activities are based on direct interaction with people and providing them with psychological assistance. It is emphasized that the best option is when the psychologist has a high level of development of social intelligence. In this case, they are characterized by sensitivity to the nature of social relationships, the ability to successfully apply a wide range of social roles, a high level of control over their own behavior, emotional self-regulation. The main methods of research of features of formation of social intelligence at the psychologist are analyzed: social and psychological adaptation, communicative and organizational inclinations, an estimation of level of sociability. The sample, stages of research are characterized and the received results of studying of features of formation of social intelligence at psychologists are analyzed.
FACTORS OF CYBERBULLYING IN ADOLESCENT ENVIRONMENT: THEORETICAL REVIEW
Authors: Titov I. , Lavrinenko V.
Published: October 2022

The article contains an analysis of the results of a theoretical analysis of the specific of cyberbullying factors in the adolescent environment and its consequences for the psychological well-being of this age representatives. The theoretical framework for understanding the concept of cyberbullying, the combination of the tendency of aggressive behavior and the specifics of the virtual environment in this phenomenon is defined. The results of studies reflecting the connections of cyberbullying with negative phenomena of the emotional sphere, a tendency to suicidal behavior, previous attitudes towards aggression, behavioral disorders and somatic phenomena were analyzed. Patterns of age, gender, and experience of participating in bullying situations as factors of cyberbullying for teenagers have been revealed.
THE PHENOMENOLOGY AND TYPOLOGY OF BIOGENIC DEPRIVATIONS
Authors: Kobylchenko V. , Omelchenko I.
Published: October 2022

The article examines the problem of deprivation analysed as a multifactorial psychological phenomenon that has a significant negative impact on children's personal development. The nature of deprivation is determined depending on the factors that generate it, namely, biogenic, sociogenic and psychogenic.

The phenomenology of biogenic deprivation is revealed, its features and consequences for children's psychosocial development are characterized.

We have determined that if a certain organic violation exists, there are always leading and concomitant types of deprivation. Accordingly, each violation basically causes a certain leading deprivation; and this fact allows us to derive a certain typology of biogenic deprivation.

Visual deprivation occurs at visual impairments, auditory deprivation does at hearing impairments, mental deprivation appears at intellectual development impairments (feeble minding), cognitive impairments does at cognitive development impairments (mental retardation), speech (communicative) one does at speech disorders, motor one does at musculoskeletal system disorders, deprivation of identity (social one) does at autistic spectrum disorders.

All types of deprivation have some common manifestations, namely: increased anxiety, decreased vital activity, frequent mood swings, unmotivated aggression, etc.
Numerical Taxonomy and Virulence Screening of Aeromonas spp. Isolated from Healthy and Epizootic Ulcerative Syndrome-Positive Fishes
Authors: TORRES J.L. , TAJIMA K. , SHARIFF M.
Published: October 2022

Numerical taxonomic analysis was done on 54 previously identified motile Aeromonas spp., including 6 reference strains. At 85% similarity value, 34 of the 54 strains were classified into 8 phenons. When the strains were acreened for virulence, phenon I proved to be the most virulent. The majority of isolates in phenon I (highly pathogenic and serologically homogenous A. hydrophila) came from fish exhibiting epizootic ulcerative syndrome (EUS), while those from phenon II (nonpathogenic and serologically heterogenous A, hydrophila) came from healthy fish. Two host species. Channa striata and Clarias sp., from which the greatest diversity of motile aeromonads was recovered.. were heavily affected by EUS.
A Mechanism to Explain Fluctuations in Population Size of the Far Eastern Sardine (Sardinops sagax melanostictus)
Authors: LI XIN-YANG
Published: October 2022

Environmental factors were examined and did not seem to be determinants of fluctuations in population size of the Far Eastern sardine. Summarizing traits of the sardine's life history and evaluating their consequences suggested that the surplus energy obtained by an individual oould be largely regulated by population size-dependent migratory distance. Examining trajectories of body length againat stock size sug­gested two distinctive proceaaes of body condition degeneration and recovezy in popu­lation growing and declining periods. All these, together with published experimental results on the relation between egg quality and larval survival for some close species, led to a hypothesis that the egg-recruit survival rate depends on adult body condition which is determined by degeneration and recovery procesaea corresponding to popula­tion growing and declining phases. The sardine's population fluctuations are broadly explained by this hypothesis.
Ethological Responses and Changes in Hemoglobin and Glycogen Content of the Common Carp, Cyprinus carpio, Exposed to Cadmium
Authors: ALKAHEM HMOUD FARES
Published: October 2022

Specimens of common carp, Cyprinus carpio, were exposed to cadmium ranging in concentrations from 5 to 8 mg 1-1• The 96 hour LC60 was found to be 6.12 mg }·1• Exposed fish showed marked changes in behavioral patterns. Hyperexcitation, fast and jerking movements, convulsion and profuse secretion of mucus were apparent in the fish exposed to cadmium. Severity and frequency of occurrence of these behaviors in­creased in higher concentrations (7-8 mg 1·1) in the beginning of treatments. Later, the fish in higher concentrations became less active and settled at the bottom. Behavior like coughing, yawning, fin flicking and chafe in fish exposed to sublethal concentra­tions (0.25-1.5 mg 1·1) of cadmium were found to be concentration dependent also. Depletion of glycogen in the liver and muscle was noted, being greater in muscle (maximum 27%) than the liver (maximum 10%) in the highest sublethal dose (1.5 mg 1-1 ) of cadmium. Hemoglobin concentration of the cadmium-exposed fish was in­creased by 4.4, 6.6, 8.1 and 8.5 per cent in concentrations of 0.25, 0.5, 1.0 and 1.5 mg 1-1, respectively.
DNA Fingerprinting as a Tool in Fish Biology
Authors: ZHANG YING-PEI , TANG YU-PING
Published: October 2022

DNA fingerprinting is a relatively new technique by which a set of polymorphic can be simultaneously detected, resulting in a pattern unique to a species, strain or individual (DNA fingerprint). The DNA fingerprinting probes applicable to fish include human minisatellite DNAs, bacteriophage Ml 3, mouse sequence related to Drosophila Per gene and some oligonucleotide sequences such as (GATA)4 and (GACA)4. The fingerprints can also be obtained by combination of a number of hypervariable single locus markers. The methods employed to reveal DNA fingerprints include hybridization and the polymerase chain reaction (PCR). With arbitrarily-primed PCR, DNA fingerprints can be obtained from a wide range of species. The technique has proven to be a powerful tool in various fields of fish biology, such as individual and stock identification and breeding.
Accumulation and Depuration of Mercury in a Catfish Heteropneustes fossilis (Pisces: Heteropneustidae) Exposed to Sublethal Doses of the Element
Authors: JAMES R.
Published: October 2022

The accumulation and depuration of mercury in exposed Heteropneustes fossilis to two sublethal levels of the element has been studied as a function of time. Exposure produced a time- and dose-dependent increase in the concentrations of mercury in all tested tissues. Animals exposed to both concentrations accumulated significant amounts of mercury, levels in the tissues decreasing in the following order: liver > gill > muscle > intestine. On transfer of the fish to uncontaminated water after 9 days of exposure, the mercury concentrations in tissues gradually declined. All tissues of catfish exposed to O .01 or O .03 ppm mercury recorded complete depuration of accumulated mercury over 37-123 days; individuals exposed to 0.03 ppm mercury took twice the time for excretion of the element as those exposed to 0.01 ppm.
The Correct Taxonomic Designation for the Southeast Asian Tinfoil Barb: Puntius schwanenfeldii or schwanefeldi?
Authors: CHRISTENSEN MIKKEL S.
Published: October 2022

The Southeast Asian tinfoil barb is a widespread and common cyprinid fish th.at has considerable potential as an aquaculture candidate. It is a member of the taxonomically disputed genus Puntius, to which the java carp, P. gonionotus, also belongs. Considerable confusion apparently exists as to the species name of the tinfoil barb, however, as a variety of spellings are utilized This paper reviews the taxonomic position of the tinfoil barb and shows that the designation Puntius schwanenfeldii Bleeker 1853: p.517 is the correct form.
Sustainable Yield of Tubificids in the Outdoor Culvert System
Authors: MOLLAH M.F.A. , AHAMED M.T.
Published: October 2022

An experiment was conducted for 160 days to culture tubificids (aquatic oligochaetes) in a medium containing 35% wheat bran, 25% cow dung, 20% mustard oil cake and 20% fine sand under running water in outdoor culverts (160 x 25 x 10 cm). A harvesting schedule of four different quantities was tested to obtain a sustainable yield. A harvest level of 30 mg-cm·2 every 10 days was more sustainable and significantly (P<0.01) better than other levels tested, with total production of 852.42 ± 4.13 mg•cm.·2 of tubificids.
Trophic Interrelationships of the Demersal Fish Assemblage in the Northwest Arabian Gulf, Iraq
Authors: ALI T.S.
Published: October 2022

The food composition of 12 fish species collected from the northwest Arabian Gulf in January-August 1990 was examined. Crabs, fish, shrimp and molluscs were the most extensively utilized. Food partitioning among the predators showed three categories: pelagophagous, mesophagous and benthophagous. According to the diet breadth of each species, three degrees of feeding specialization were not.ed: specialized (Trachionotus blochi, Chirocentrus dorab, Arius thalassinus, Otolithes ruber, Triacanthus biaculeatus and rays), less specialized (Upeneus sulphureus, Scolopsis phaeops and Johnius sina) and generalized feeders (sharks, Atropus atropus and Therapon theraps). The fish assemblage divided significantly into seven groups depending on the diet overlap between each pair of species. The overlap among the investigated species was 12.4%.
Impacts of the Production Responsibility System on the Development of Freshwater Pond Fish Culture in China
Authors: LEUNG PINGSUN
Published: October 2022

Fisheries production in China has increased tremendously from one million tonnes in 1951 to over 12 million tonnes in 1990. Increases in aquaculture production and the implementation of the production contract responsibility system in 1978 have been identified as two key factors contributing to this rapid growth. In 1990, freshwa­ter aquaculture accounted for about 36% of total fisheries production. The fastest growing component of freshwater aquaculture production is pond fish culture. This paper traces the development of freshwater pond fish culture since the economic re­form. Economic, social and technological factors affecting national and regional devel­opment trends are examined. Discussions are based largely on recent field visits by the authors to fish farms in various parts of China, and several case studies.
Analisis Ulasan Pelanggan Menggunakan Multinomial Naïve Bayes Classifier dengan Lexicon-Based dan TF-IDF Pada Formaggio Coffee and Resto
Authors: Anggina Sarah , Setiawan Nanang Yudi , Bachtiar Fitra A.
Published: October 2022

Formaggio Coffee and Resto Tangerang menyajikan hidangan western dengan rasa yang disesuaikan pada selera masyarakat Indonesia. Adanya peningkatan jumlah restoran di Kota Tangerang setiap tahunnya membuat Formaggio Coffee and Resto harus memiliki keunggulan kompetitif dengan cara meningkatkan kepuasan pelanggan. Kepuasan pelanggan bisa didapatkan jika ekspektasi pelanggan terpenuhi. Pihak manajemen Formaggio menganggap kritik dan saran yang diberikan oleh pelanggan merupakan sebuah hal positif yang dapat meningkatkan kinerja mereka. Namun, banyaknya ulasan pelanggan yang tersebar di berbagai situs membuat pihak restoran sulit dalam mengelola pendapat pelanggan. Hal tersebut dapat diatasi dengan melakukan web scraping pada situs Traveloka, PergiKuliner, Zomato, dan Google Review, dimana data yang berhasil terkumpul adalah sebanyak 741 ulasan dengan rentang waktu mulai tahun 2018 hingga tahun 2021. Kemudian, salah satu cara untuk mendapatkan informasi dari ulasan pelanggan adalah dengan melakukan analisis sentimen menggunakan fitur kamus Indonesian Sentiment Lexicon (InSet Lexicon) dan pembobotan TF-IDF, serta algoritme klasifikasi Multinomial Naïve Bayes. Model klasifikasi selanjutnya diuji menggunakan Confusion Matrix dengan empat parameter, yaitu accuracy, recall, precision, dan f1-score. Didapatkan nilai rata-rata dari setiap parameter tersebut sebesar 95%, 68%, 85%, dan 72%. Hasil penelitian selanjutnya divisualisasikan ke dalam sebuah dashboard dan diuji menggunakan kuesioner System Usability Scale (SUS) dengan nilai akhir sebesar 67,5 yang berarti dashboard tersebut dapat diterima dengan baik oleh pihak manajemen Formaggio.
Perancangan Sistem Informasi Akuntansi Harga Pokok Produksi Berdasarkan Job Order Costing
Authors: Azahra Sayyidah Nabila , Supriyati S
Published: October 2022

Transaksi digital yang semakin berkembang membuat penggunaan teknologi informasi dalam berbagai bisnis perusahaan semakin dibutuhkan. Pada perusahaan manufaktur terdapat perhitungan harga pokok produksi (HPP) yang merupakan bagian terpenting dalam menghitung biaya yang dikeluarkan saat proses produksi. Namun, permasalahan human error atau kesalahan manusia sering muncul saat perhitungan HPP masih dilakukan secara manual salah satunya adalah di perusahaan liwet Asep stroberi. Tujuan penelitian ini adalah untuk merancang sistem informasi akuntansi harga pokok produksi pada liwet Asep stroberi yang saat ini penentuan harga pokok produksinya belum sesuai dengan standar akuntansi. Dengan ketidakstabilan harga pokok produksi dapat mempengaruhi kenaikan biaya produksi yang mengakibatkan laba atau rugi perusahaan sehingga tidak dapat terpantau oleh manajer, selain itu pencatatan akuntansi belum terkomputerisasi sehingga dapat menghambat waktu pengerjaan laporan harga pokok produksi. Sistem informasi yang dirancang oleh penulis menggunakan bahasa pemrograman Hypertext Preprocessor atau PHP dan database postgreSQL. Model perancangan sistem informasi yang digunakan adalah diagram konteks, flowchart dan model pengembangan sistem menggunakan model Software Development Life Cycle (SDLC) air terjun (waterfall). Tujuan dari perancangan sistem ini  adalah membantu dalam proses pencatatan, perhitungan dan laporan harga pokok produksi secara efektif dan efisien. Hasil dari penelitian ini adalah rancangan sistem informasi akuntansi perhitungan harga pokok produksi berdasarkan job order costing.
ABRASCO e FIOCRUZ: pelo aperfeiçoamento do SUS
Authors: Onocko-Campos Rosana Teresa
Published: October 2022

A Atenção Primaria é uma estratégia defendida pela Organização Mundial da Saúde carrega princípios como a longitudinalidade dos cuidados, universalidade, equidade e integralidade. Nos últimos anos, a atenção primaria brasileira se expandiu, alcançou populações com dificuldade de acesso e reduziu desigualdades brasileiras. Entretanto, esse sofisticado arcabouço de trabalhadores, e seu complexo arranjamento territorial precisavam de um suporte de formação e preceptoria adequados. Foi nesse contexto que o PROFSAÚDE foi criado em 2016 como estratégia de formação de recursos humanos constituindo uma ampla rede de capacitação espalhada pelo imenso território nacional e aglutinando inúmeras entidades de ensino superior. O PROFSAUDE e suas estratégias formadoras serão fundamentais para novos problemas advindos da desorganização dos serviços trazida pela pandemia, do agravamento da crise social com empobrecimento e desemprego da população.
Articulação entre Práticas Integrativas e Promoção da Saúde: ações coletivas com acupuntura na Estratégia Saúde da Família
Authors: Oliveira Andréa Mauricio de Gouveia , Pezzato Luciane Maria , Mendes Rosilda
Published: October 2022

As Práticas Integrativas e Complementares em Saúde(PICS) são práticas terapêuticas reconhecidas pela Organização Mundial de Saúde e englobam várias práticas corporais e comportamentais, sendo uma delas a acupuntura. Esta pesquisa teve como objetivo refletir uma experiência inovadora que articulou uma prática de acupuntura com a promoção da saúde em uma Unidade de Saúde da Família. Foi realizado um estudo descritivo e analítico, de natureza qualitativa, que utilizou rodas de conversas e registros em diário de campo como estratégias para produção de dados. Este estudo possibilitou uma ampliação no acolhimento das demandas dos usuários, com estreitamento de vínculo entre a equipe de saúde e a comunidade, contribuindo para a desmedicalização do cuidado. Percebemos a ampliação da oferta da clínica, o aumento do conhecimento das PICS, com incentivo à desmedicalização, autocuidado, participação de atividades em grupo, troca de saberes e inserção de estratégias  capazes de colaborar com o processo de reconstrução de modos de viver a vida de pessoas que buscam o serviço de saúde.
Abordagem de organização facilitada para otimização de testes rápidos de detecção de infecções sexualmente transmissíveis: um relato de experiência
Authors: Ferreira Mara Gabriela Brasileiro de Lucena , Santos Romário , Santos Barbosa Tamires Correia dos , Da Silva Luís Roberto , Meneses Macedo Laiz Mara , Lucena Madhalena Lindha Ferreira de , Correia Divanise Suruagy , Monte Mello Taveira Maria das Graças
Published: October 2022

Ao confrontar a elevação dos números de casos de infecções sexualmente transmissíveis, em especial a AIDS, a sífilis e as hepatites virais do tipo B e C; constatamos a necessidade de uma testagem mais expressiva da população por meio da facilitação do acesso aos insumos e demais materiais necessários para os procedimentos, visando à otimização do tempo dos usuários do serviço público de saúde e gerando uma maior adesão aos mecanismos de testagem. A facilitação do acesso aos materiais para  testagem gerou uma diferença de seis vezes no número de testes quando comparados o primeiro mês do experimento e o último. A maior modificação, no entanto, não se concentrou no aparecimento da bancada com seu protocolo guia, mas sim na participação conjunta de todos os profissionais da equipe de saúde, buscando compreender e se envolver nos processos de testagem, de modo que todos estivessem aptos a realizar adequadamente os procedimentos assim que se fizesse necessário. Evidenciou-se o potencial beneficiador que a facilitação do acesso aos testes rápidos, com a devida capacitação conjunta da equipe disponível, produz efeitos notórios no rastreio e no diagnóstico precoce de infecções sexualmente transmissíveis de elevadas prevalências.
Percepção dos profissionais do Programa Mais Médicos quanto à adesão aos instrumentos de comunicação entre as Redes de Atenção à Saúde e a Atenção Primária
Authors: Arruda Ana Flávia , Sousa Eduardo Sergio Soares , Lima Moises Diogo de , Paiva Melina Pereira Fernandes , Lima Maria Celeste Dantas Jotha de
Published: October 2022

O artigo objetiva analisar a percepção dos profissionais do Programa Mais Médicos quanto à adesão aos instrumentos de comunicação entre os pontos de atenção das Redes de Atenção à Saúde. Sua importância diz respeito à necessidade de se analisar o grau de adesão aos instrumentos e qualificar a ocorrência da comunicação entre os entes da rede, na medida em que se reconhece a necessidade de manter informado o profissional detentor da coordenação do cuidado e devolver a ele a responsabilidade pela condução dos indivíduos usuários da rede. Os resultados demonstraram a baixa percepção do retorno dos registros dos usuários da rede aos pontos de atenção, independentemente da macrorregião (P = 0,094). Esse resultado demonstra a necessidade de trabalhar a qualificação das atividades da rede de atenção a fim de valorizar a necessidade das informações oriundas do processo de contrarreferência.
Pesquisa de satisfação dos médicos de família do Brasil com o uso de prontuários eletrônicos.
Authors: Baule Cíntia de Paula , Fidalski Solena Ziemer Kusma , Chong Neto Herberto José , Carvalho Max Luiz de , Dobrychtop Ivan
Published: October 2022

A informatização da medicina busca potencializar o sistema de saúde, mas diversas dificuldades são encontradas na usabilidade dos sistemas pelos profissionais. No Brasil, sabe-se muito pouco sobre a percepção dos médicos sobre o uso de prontuários eletrônicos. O objetivo desta pesquisa foi identificar o nível de satisfação dos médicos de família com o uso de prontuários eletrônicos. Trata-se de pesquisa observacional transversal, com aplicação de questionário para a avaliação do grau de satisfação dos usuários de prontuários eletrônicos. Para a análise, foi utilizada a metodologia de mineração de dados com ferramentas específicas. O alto nível de satisfação esteve relacionado à capacidade de o prontuário prevenir erros, prover prescrição rápida e fácil, ajudar a atender mais pacientes, facilitar a discussão de casos e realizar tarefas. Já a insatisfação esteve relacionada a suporte técnico ruim, falta de ferramentas de suporte à decisão clínica, ser empecilho à relação médico paciente e alertas ruins. Apesar do nível de satisfação geral ser baixo, os médicos demonstraram gostar de usar o prontuário eletrônico. Este estudo é uma oportunidade para reflexão sobre as demandas mais urgentes no aprimoramento desses sistemas e para planejamento de ações futuras.