bluuebunny/crossref_metadata_2025 huggingface dataset:
El método simplex como herramienta en la optimización de recursos de una empresa agroindustrial
Authors: Ramírez Cortés Verónica , Vázquez Alamilla Miguel Ángel , Ruiz Reynoso Adriana Mercedes
Published: December 2022

El objetivo de la presente investigación es evaluar la asignación óptima de los recursos de una empresa agroindustrial dedicada a producción de nopal en salmuera en tres presentaciones, a través del método simplex de programación lineal usando la metodología de investigación de operaciones. Como herramienta tecnológica se utiliza el complemento Solver de la hoja de cálculo de Excel. El tema es relevante ya que, en México, se identifica alta mortandad de empresas en sus primeros años sobre todo en las micro y pequeñas, mientras que, las que permanecen en un mercado dinámico y competitivo manifiestan problemáticas con relación a la toma de decisiones que garantice una asignación eficiente de recursos. De los principales hallazgos destaca la construcción de un modelo matemático aplicando el método simplex para calcular el nivel de producción óptimo que minimice los costos de producción, resultando útil su aplicación para contribuir en la toma de decisiones de los empresarios.
Effects of Glyphosate-Resistant Genetically Modified Soybean on Blood Biochemical Indexes, Hepatopancreatic Antioxidant Capacity and Tissue Morphology of Cyprinus carpio
Authors: Zhang Jiaguo , Yu Taotao , Huang Xiaoxia , Ma Qianqian , Zhang Changfeng , Zhou Qunlan
Published: December 2022

The juvenile carps (Cyprinus carpio) were fed diets with four protein sources (15% and 30% glyphosate-resistant genetically modified (GM) named GM 15 and GM 30, respectively, and 15% and 30% non-genetically modified (NGM) soybean named NGM 15 and NGM 30) for 180 days. Results showed that alkaline phosphatase (ALP) activity for the GM30 group was significantly lower than that of the NGM30 group. The activity of glutathione peroxidase (GSH-Px) in the hepatopancreas of carp for the GM30 group was significantly higher than that of the NGM15 group (P<0.05). And the content of malondialdehyde (MDA) for the GM30 group was higher than that of the NGM30 group during the whole culturing process (P<0.05). The activity of catalase (CAT) for the GM30 group was significantly lower than that of the NGM30 group during 60 days and 180 days (P<0.05). While no significant differences were observed in the growth indexes, organ indexes, and muscle nutritional components of carp among the four groups (P>0.05). This study indicates that it may aggravate the damage degree of intestinal epithelial cells of carp and more easily cause liver cell damage in the short term when the amount of GM soybean in the feeds was 30%. Therefore, higher glyphosate-resistant GM soybean may have adverse effects on the carp’s serum, intestinal, and hepatopancreas and considerably reduce the hepatopancreatic carp’s antioxidant capacity.
Selected topics in Cohomology of non-arithmetical groups (algebras) and open questions
Authors:   Sapienza University of Rome, Faculty of Medicine and Pharmacy, Viale Regina Elena, 324 - 00185 Rome, Italy, Maria Lecian Orchidea ,   Sapienza University of Rome, Faculty of Medicine and Dentistry, Piazzale Aldo Moro, 5 - 00185 Rome, Italy,   Kursk State University, Faculty of Physics, Mathematics and Information Sciences, Chair of Algebra, Geometry and Didactics of Mathematics Theory, ul. Radis’c’eva, 33, aud. 201, Kursk, Russia
Published: December 2022

Selected topic in the cohomology of non-arithmetical groups algebras and grouppal structures are chosen and reviewed. The basics formalisms are recalled. The comparisons between the different approaches are proposed, from which new open questions arise; in particular, the application of the method of satellites to the study of non- arithmetical grouppal structures is evidentiated to request the definition of new structures in the calculation of the irreducible characters
Cutaneous Mastocytosis: Diagnosis and Treatment for the Physician of First Contact
Authors:   Universidad del Valle de México, Campus Reynosa. Reynosa, Tamaulipas, México., Rivera Cinthia Mariel Constantino , Muñoz Edit Cano ,   Facultad de Estudios Superiores Zaragoza. Universidad Nacional Autónoma de México. México., Baca Daniela Quintero ,   Facultad de Medicina de la Universidad Nacional Autónoma de México. México., Lúa Carolina Hernández ,   Universidad de Guadalajara. Guadalajara, Jalisco, México., Peña Gerardo Arauz ,   Facultad de Medicina de la Universidad Nacional Autónoma de México. México.
Published: December 2022

Mastocytosis is one of eight subcategories of neoplasms. Classification of Myeloproliferative Tumors of Lymphoid Tissues and hematopoietics of 2008 of the World Health Organization; is a heterogeneous group of myeloproliferative diseases that distinguished by excessive proliferation of mast cells morphologically and immunophenotypically atypical, in addition to the accumulation of these cells in one or more organs or tissues, including the skin, bone marrow bone, liver, spleen, and lymph nodes
A Case of Pemphigus Vulgaris in a Patient with Human Immunodeficiency Virus
Authors:   Department of Internal Medicine, Hospital of High Specialty of Veracruz SESVER, Veracruz, Mexico, Cruz Charit Nayelly Chang , la Cruz Alfredo Bautista de ,   Department of Internal Medicine, Hospital of High Specialty of Veracruz SESVER, Veracruz, Mexico, Calixto Estanislao Antonio ,   Department of Internal Medicine, Hospital of High Specialty of Veracruz SESVER, Veracruz, Mexico
Published: December 2022

Pemphigus vulgaris is the most common variant of autoimmune chronic blistering skin diseases. Its appearance in patients infected with acquired immunodeficiency virus (HIV) is rare. A 40-year-old woman is reported, who presented skin lesions in 90% of the body surface, characterized by blisters of 3 to 4 cm that, when broken, left denuded areas, excoriations and pruritic meliceric crusts. A skin biopsy was performed that showed a characteristic pattern of pemphigus vulgaris. Elisa for HIV positive. She evolved with septic shock and died 72 hours later. Understanding the relationship between HIV and autoimmune blistering disorders can help guide the therapeutic and prognostic management of these patients. Proposed mechanisms include molecular mimicry, polyclonal B-cell stimulation, and highly active antiretroviral therapy possibly associated with immune restoration. Clinically, these patients may present limited mucosal symptoms or develop multiple erosions that may spread, merge, and progress to exfoliative erythroderma. Glucocorticoids serve as the first line of management; however, they can have important adverse effects such as infectious complications that pose a therapeutic challenge for the doctor and could influence mortality.
The Influence of Pralima Kawruh Budha on Tengger Tribe Trade Accounting
Authors:   Universitas Negeri Malang & Semarang Street 5, Sumbersari, Lowokwaru, Malang Citty, East Java, Indonesia 65145, Firmansyah Rizky , Rizky Izzalqurny Tomy ,   Universitas Negeri Malang & Semarang Street 5, Sumbersari, Lowokwaru, Malang Citty, East Java, Indonesia 65145, Miftahurahman Dandy ,   Universitas Negeri Malang & Semarang Street 5, Sumbersari, Lowokwaru, Malang Citty, East Java, Indonesia 65145
Published: December 2022

Local wisdom can affect social activity patterns, including accounting practices in a community group. Every activity, including accounting practices, carried out by Tengger tribe based on their local wisdom, namely Pralima Kawruh Budha. This research aim to analyze the influence of Pralima Kawruh Budha on Tengger tribe trade accounting. This research conducted using ethnomethodology interpretive approach to seek a clear picture of the Tengger tribe trade accounting practice based on Pralima Kawruh Budha. The data sources used in this study are primary sources derived from field observations and interviews. According to the research result, many Tengger tribe people have forgotten Pralima Kawruh Budha. Even so, the values that exist in Pralima Kawruh Budha are still reflected in almost all activities of the Tengger tribal community.
Comparative Analysis of Financial Performance Before and During the Covid-19 Pandemic Period 2018-2021 (Subsector Automotive and Component Companies Listed on Idx)
Authors:   Departemen Administrasi Bisnis, FISIP, Universitas Diponegoro, Ningrum Linda Ayu , Saryadi Saryadi ,   Departemen Administrasi Bisnis, FISIP, Universitas Diponegoro, Purbawati Dinalestari ,   Departemen Administrasi Bisnis, FISIP, Universitas Diponegoro
Published: December 2022

Covid-19 pandemic triggered a massive turmoil in uncertainty and big impact on health care, mobility, social activities and economic growth. That low economic growth lead business activities of companies in transformation. This study aims to observe the differences in financial performance of automotive and component companies listed on Indonesia Stock Exchange before and during Covid-19 pandemic 2018-2021 period. The population used is automotive and component companies listed on Indonesia Stock Exchange, determined based on the purposive sampling method with the criteria which is companies have been publishing their financial statement and annual report until 2021, resulting 10 companies as research samples. Research type in this study is event study. Secondary data used as sourced data. Analysis method of data using descriptive test and wilcoxon signed ranked test, with a software SPSS ver 26. The result shows there were no significant difference in the liquidity measured by current ratio, along with profitability measured by return on asset, return on equity and net profit margin in the automotive and component companies between before and during pandemic period. Meanwhile, companies’ activity measured by receivable turnover and total asset turnover have significant difference between before and during pandemic period.
Academics' Work Life Balance During Pandemic
Authors:   Entrepreneurship Department, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Indonesia, Yudha Amriel Egan Evanzha , Nuswantara Dian Anita ,   Accounting Department, Universitas Negeri Surabaya, Indonesia, Hariyana Nanik ,   Management Department, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Indonesia, Izaak Wilma Cordelia ,   Management Department, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Indonesia, Yuhertiana Indrawati ,   ACCOUNTING DEPARTMENT, UNIVERSITAS PEMBANGUNAN NASIONAL “VETERAN” JAWA TIMUR, INDONESIA
Published: December 2022

Some problems occur regarding work-life balance during the pandemic. This study tries to understand how lecturers face stressful situations related to job changes from traditional working in the office (before the pandemic) to working from home (pandemic) and then working from anywhere (after the pandemic). Data were collected from observations and in-depth surveys at two universities in Surabaya, Indonesia. This study uses a qualitative phenomenological approach. The research focuses on how lecturers respond to changes in work patterns during the pandemic. There were 26 informants interviewed, consisting of lecturers and administrative staff. In addition to interviews, this research actively participates in and collects various documents related to policies during the pandemic. There are three findings in this study. First, universities respond quickly to changes related to the development of the Covid-19 virus following government regulations regarding classroom learning policies. Second, lecturers and administrative staff continue to carry out their activities during the pandemic. Lecturers continue to perform their tri dharma, teaching, research, and community service. These activities use technology through Online Learning. In the new normal era, although learning has been carried out offline in the classroom, online learning techniques are still. Third, changing work patterns, especially during the lockdown, where work done at home creates pressure. There are two types of pressure, pressure due to multiple roles that must be carried out simultaneously at home and pressure due to the mandatory use of online learning technology.
Solutions to Improve the Quality of Tourism Activities for Some Trade Villages Rural Rural District Can Gio District, Ho Chi Minh City
Authors:   Ly Tu Trong College Ho Chi Minh City, Vietnam, Thi Huyen Dinh , Phuoc Trong Nguyen ,   Ho Chi Minh City University of Food Industry, Vietnam
Published: December 2022

The tourism industry contributes a significant portion of the gross national economic product in many countries. Especially, for Vietnam, the tourism industry is now considered as one of the three key economic sectors; focused on investment; constantly developing and making positive contributions to the national economy. Tourism development promotes economic sectors that support development such as transportation; post and Telecommunication; insurance; Financial services; accommodation and food services. The developed tourism industry also brings a large commodity consumption market; thereby promoting rapid growth of gross national economic product. Craft village tourism in Ho Chi Minh City, especially traditional craft villages in suburban rural areas such as Can Gio district, has become a new trend of the world. The article focuses on clarifying tourism activities for a number of rural craft villages and proposes some solutions to improve the quality of tourism activities in Can Gio district, Ho Chi Minh City.
Value-at-Risk Estimation Using an Interpolated Distribution of Financial Returns Series
Authors: Shaker-Akhtekhane Saeed , Poorabbas Solmaz
Published: December 2022

Abstract

This paper develops a model for estimating Value-at-Risk (VaR) from the historical return series. The proposed method uses spline interpolation to represent the empirical probability distribution of the return series. The approach developed in this paper is easy to implement using available programming platforms, and it can be generalized to other applications that involve estimating empirical distribution. In order to check the validity of the model, we use established back-testing methods and show that the model is robust to the changes in sample size and significance levels used to estimate VaR. We test the model against some similar distribution-based models using historical data from S&P500 index. We show that Value-at-Risk estimation based on the proposed method can outperform common historical, parametric, and kernel-based methods. As a result, the method can be useful in the context of validation of market risk models.

JEL classification numbers: C52, C63, G17, G32.
Keywords: Value-at-Risk, Non-parametric estimation, Empirical distribution, Spline Interpolation.
Transmission of Tuberculosis and Reproduction Number Using Lyapunov Function of SIR Model
Authors: Md Noor Mohd Rahimie Bin , Zaid Mohamed Zuheel Bin , Rosli Rozaimie Bin , Hairudin Mohamad Danial Bin , Syed Adnan Sharifah Athirah Bt , Abdul Malek Mohd Azry Bin , Mustapha Muhammad Firdaus B. , Mohd Yasin Ahmad Bukhari Bin , Kairan Omar B.
Published: December 2022

This paper studies the mechanism of transmission of Tuberculosis (TB) caused by the mycobacterium tuberculosis bacteria. TB is an airborne disease that endangering human population globally. Mathematical modelling of tuberculosis was developed using the Susceptible-Infected-Recovered (SIR) model in this analysis. The model generated by the four-dimensional, nonlinear dynamic system is reduced to three dimensions, with some assumptions. Then, the model will be analyzed by creating a mathematical theorem that will prove the existence of a TB event, the disease-free equilibrium phase, and the TB endemic disease stage. By using the Lyapunov function method, the three theorems can be proved. The basic reproduction number R0 also can be obtained from the model. If the basic reproduction number R0 ≤ 1, then the disease-free equilibrium is global asymptotically stable and if R0 > 1, then the endemic equilibrium is asymptotically stable globally. Carrying out a simulation using data in a selected region, the result of the model successfully describes and forecast the number of TB cases and it may also be used for assessing the TB disease status.
Interpretações e poderes em disputa: o ressurgimento do Centrão na política brasileira
Authors: Bezerra Gabriella Maria Lima , Vieira Márcia Paula
Published: December 2022

A vitória de Eduardo Cunha (PMDB/MDB-RJ) para a presidência da Câmara dos Deputados, em 2015, emplacou nas notícias sobre política o termo “centrão”. Diante da crescente utilização dessa denominação e da reviravolta dos poderes desse grupo de partidos nas relações entre executivo e legislativo no governo Bolsonaro, buscamos neste artigo: 1) refletir sobre o uso do termo nos debates políticos brasileiros, identificando, a origem dessa denominação e os sentidos correntes dessa caracterização, como também, 2) analisar as possíveis transformações na disputa política, com o seu ressurgimento e ascendência.  No trabalho reconstruímos a origem do termo e seu ressurgimento, identificando a metamorfose da sua aplicação. Analisamos os significados do uso do termo “Centrão” nos debates políticos nacionais atuais nas colunas da Folha de São Paulo no período de 2016 a 2020. Como desdobramento, buscamos identificar os partidos vinculados ao Centrão no governo Bolsonaro e a composição das bancadas. Para finalizar, recuperamos o debate dos estudos legislativos sobre os incentivos institucionais e o comportamento parlamentar no Brasil, destacando a complexidade e o desafio analítico para a ciência política brasileira, na berlinda entre a crítica e uma visão moralizante da política. Consequentemente, nesse exercício argumentativo, destacamos que as contradições que o uso do termo carrega incentiva a ampliação analítica do fenômeno, especialmente, a inclusão dos incentivos institucionais para a compreensão do comportamento dos atores parlamentares identificados com esse bloco.
O eleitor radical e o paradoxo dos sistemas eleitorais conflitantes
Authors: Simoyama Felipe , Bueno Ricardo Luiz Pereira
Published: December 2022

Os estudos sobre as implicações do teorema do eleitor mediano geralmente se relacionam com o sistema eleitoral majoritário – por exemplo, as eleições para os cargos do poder executivo no Brasil. Por outro lado, a literatura atual argumenta que o referido teorema não se aplica ao sistema eleitoral de lista aberta, carecendo, porém, de uma demonstração formalizada sob o prisma da teoria de jogos. O objetivo desse estudo é propor um modelo para o sistema eleitoral de lista aberta, com utilização de teoria de jogos, visando explicar o comportamento estratégico dos jogadores envolvidos e de que forma a diferença entre os sistemas eleitorais pode impactar o processo de formulação de políticas públicas. O método utilizado foi a modelagem de três jogos simplificados e não-cooperativos. Cada jogo foi simulado com diferentes estratégias dos jogadores. Os resultados sugerem que a diferença entre os sistemas eleitorais gera incentivos distintos aos jogadores, criando um paradoxo que poderia gerar desajustes e instabilidade política, impactando o processo de formulação de políticas públicas no Brasil. Esse estudo revela que a teoria de jogos ainda apresenta muitas possibilidades de exploração pela ciência política, especialmente para a construção de modelos simplificados de temas ainda não abordados, além de permitir o desenho de modelos mais sofisticados para tratar de assuntos já estudados sob a luz dessa teoria.
Da judicialização da política à atuação dos ministros do Supremo Tribunal Federal no Twitter
Authors: Carvalho Isadora Leal , Santana Luciana
Published: December 2022

Com a judicialização da política, é cada vez mais evidente que os ministros do Supremo Tribunal Federal (STF) são atores políticos independentes no processo de formulação das políticas públicas. De forma que, com expansão Tecnologias de Informação e Comunicação (TIC’s), aos quais os Ministros do STF não são imunes, é possível que a atuação política dos ministros do STF esteja sendo estendida ao campo virtual. Com este enfoque, o presente artigo tem como objetivo averiguar o uso do Twitter pelos Ministros do STF como forma de expressão política. Partindo da hipótese de que a atuação política dos ministros do STF no Twitter é um movimento em progressão, ao tempo que o Twitter funciona como instrumento que permite a comunicação entre o Judiciário e o povo, contribuindo para a construção de decisões através de um processo dialético entre os membros do Judiciário e a sociedade, serão identificados quais dos ministros dispõem de conta, a forma com a qual descrevem a si mesmos, a data de criação da conta, o número de seguidores e a quantidade de publicações (ou tweets) realizadas.
La importancia de los consensos y guías clínicas en la práctica médica
Authors: Campos-Miño Santiago
Published: December 2022

Existen diversos tipos de documentos que se desarrollan con el propósito de asistir al médico en la toma de decisiones diagnósticas y/o terapéuticas. Como ejemplos podemos citar el artículo de posicionamiento (position paper), las guías de práctica clínica (clinical practice guidelines), también llamados protocolos clínicos, y los consensos clínicos (clinical consensus statement).
La experiencia de implementar una historia clínica electrónica en siete centros en menos de un año
Authors: Fernandez Ariel Leonardo , Agostinelli Mercedes Salomé , Arias López María del Pilar , Urrutia Miguel Angel , Maestri Walter
Published: December 2022

Introducción: Extensa evidencia publicada sugiere que la implementación de una historia clínica electrónica (HCE) tiene potencial de mejorar la calidad de la atención, disminuyendo errores médicos causados por falta de coordinación, comunicación, pérdida de información, etc. Las dificultades encontradas en el proceso de informatización varían según la infraestructura local. Nuestro objetivo es describir un modelo de implementación exitoso de una HCE en un medio con un grado de informatización institucional y regional heterogéneo que pueda resultar útil en similares escenarios. Métodos: Descripción de una implementación llevada a cabo por un equipo multidisciplinario, utilizando un proceso estandarizado y un modelo sustentado en compromiso y apoyo de los referentes institucionales, comunicación efectiva del proyecto a todos los actores, planificación del entrenamiento y monitoreo de las etapas predefinidas. Resultados: El modelo de implementación descripto permitió poner en producción una HCE en menos de un año en siete centros (ambulatorios e internación). Más de 2000 usuarios recibieron entrenamiento personalizado en su ámbito de trabajo, focalizado en sus necesidades. El éxito de la implementación radicó en alcanzar el compromiso del nivel ejecutivo y de los líderes locales sumado a una adecuada planificación y a la adaptación del modelo a la cultura organizacional. Disponer de un equipo de implementación para brindar a los usuarios soporte en tiempo y forma y adecuado a sus necesidades fue también clave para el éxito del proceso. Conclusiones: La implementación de una HCE usando un modelo estandarizado permitió disminuir la variabilidad del proceso, mejorar los resultados finales y dejar la estructura preparada para continuar ampliando la informatización de los centros.
Estadística descriptiva: una introducción al análisis de datos exploratorios univariados y bivariados
Authors: Velasco Maria Carolina , Zhao Isaac
Published: December 2022

Este artículo es una guía práctica sobre el análisis exploratorio de datos (EDA) para investigadores con conocimientos básicos en estadística. EDA ayuda a examinar las relaciones, los patrones y las anomalías de los datos con el fin de determinar la dirección de la investigación y los métodos estadísticos a seguir. Mediante ejemplos prácticos con código en R, el estudio equipa a los lectores con el conocimiento y las habilidades para extraer información valiosa de estadísticas descriptivas y visualizaciones.
Manejo laparoscópico de un embarazo ectópico accidentado. Reporte de caso y revisión de la literatura
Authors: Macías Corral Ginger , Macías Zambrano José , Paredes Lucero Karen , Cárdenas Sacoto José
Published: December 2022

El embarazo ectópico se caracteriza por la implantación anormal del blastocisto fuera de la cavidad uterina. Afecta aproximadamente al 2% de las embarazadas siendo la trompa uterina, el lugar de implantación anómalo más frecuente. La principal complicación es la ruptura de la trompa uterina con la subsecuente hemorragia y riesgo de alteración hemodinámica que amenace la vida de la paciente. El embarazo ectópico puede ser tratado de forma conservadora utilizando metotrexate, y en forma quirúrgica, ante la sospecha de ruptura por la presencia de hemoperitoneo. Tradicionalmente se ha elegido la cirugía abierta o laparotomía, cuando hay presencia de hemoperitoneo; no obstante, en los últimos años la cirugía laparoscópica se ha presentado como una nueva alternativa, segura y con mayores beneficios para los pacientes. A continuación, se reporta el caso clínico de una mujer embarazada que presenta un embarazo ectópico accidentado más hemoperitoneo masivo, manejado de forma exitosa con cirugía laparoscópica, aprovechándose, además, la oportunidad para realizar una revisión bibliográfica del tema.
Vacunación contra SARS-CoV-2 para embarazadas o madres en periodo de lactancia. Documento de posicionamiento del comité de nutrición pediátrica de SENPE (Sociedad Ecuatoriana de Nutrición Parenteral, Enteral Clínica y Metabolismo de Pichincha)
Authors: Moscoso M. Paúl
Published: December 2022

Para agosto del 2021, el nuevo coronavirus SARS-CoV-2, responsable de la enfermedad denominada COVID-19, ha afectado a mas de 210 millones de personas y ha provocado la muerte de más de 4 millones de seres humanos. En el Ecuador han sido confirmados 501.049 casos con 32.223 fallecidos.

Las mujeres embarazadas pueden tener un mayor riesgo de enfermedad grave y muerte causadas por COVID-19 en comparación con las mujeres no embarazadas, sobre todo en el tercer trimestre o con factores de riesgo como edad materna avanzada, obesidad, hipertensión crónica y diabetes pregestacional. Los estudios actuales no demuestran que la infección por el SARS-CoV-2 durante la gestación se asocie a resultados perinatales desfavorables como aborto o parto prematuro.
GAPs o Brechas en las Guías para Latinoamérica
Authors: López-Herce Jesús , Escalante-Kanashiro Raffo
Published: December 2022

Métodos para detectar pacientes en riesgo de parada cardiaca y utilidad del equipo de respuesta rápido para disminuir la frecuencia de PC y resultados de la reanimación. La mejoría de los resultados en la RCP se ha debido fundamentalmente a una detección y tratamiento precoz de la PC. Aunque se han desarrollado diversos sistemas para detectar precozmente a los niños que tienen riesgo de PC y los equipos de respuesta rápida, no existen suficientes evidencias científicas1 ni estudios que hayan comprobado su utilidad en los países latinoamericanos.
Ruptura de Válvula Aórtica por trauma torácico cerrado
Authors: Santamaría Naranjo Gabriela
Published: December 2022

Aunque poco frecuente la insuficiencia aórtica por rotura de válvula, secundarla a un traumatismo cerrado de tórax representa un verdadero desafío para el clínico por su alta mortalidad a corto plazo siendo imprescindible un diagnóstico precoz.
Cardiopatía Isquémica
Authors: Parra Parra Martha
Published: December 2022

Las enfermedades cardiovasculares comprenden un grupo de desórdenes del corazón y de los vasos sanguíneos, entre los que se incluyen; cardiopatías isquémicas, enfermedades cerebrovasculares, arteriopatía periféricas cardiopatía reumática, cardiopatías congénitas, trombosis venosas profundas y embolias pulmonares.
Disección de tronco coronario izquierdo como complicación post cateterismo cardiaco. Resolución por cirugía de Revascularización miocárdica de Emergencia
Authors: García Matamoros Washington , Peña Morán John , Rodríguez Cedeño Nataly , Gilbert Mónica , Zúñiga Bohorquez Juan
Published: December 2022

La disección coronaria es la separación patología de las capas de la arteria coronaria. Esta puede ocurrir por el catéter guía o filamento guía dentro del lumen del vaso, por la utilización de otros dispositivos tales como catéter de extensión a la realización de la técnica (mother and child) o la expansión excesiva del balón o del stent.
Infección por COVID 19 y angiosarcom a cardíaco una combinación letal
Authors: Finke Barriga Ana Gabriela , Zavala Segovia Aldo
Published: December 2022

Revisión y presentación de un caso inusual de angiosarcoma cardiaco primario, resaltando la importancia de un adecuado manejo diagnóstico y terapéutico, en épocas de pandemia, donde un error puede resultar mortal.
Effect of vermicompost and organic matters soil application on yield, fruit physical and chemical composition of H116 pomegranate trees
Authors: Hassan, M. Ahmed  , Laila, F. Hagagg  , Tamer M. Abd El-Razik  , Eman, S. Elhady
Published: December 2022

Pomegranate trees are one of the most important economic fruit crops that bear cultivation in arid and high temperature zones, it also bears the increase in salinity in the soil and irrigation water. Pomegranate fruits are characterized by their health benefits and contain a large amount of nutrients and antioxidants. Vermicompost is one of the organic fertilizers used recently in the field of agriculture, also it is characterized by containing nutrients and natural growth regulators that are important for the growth of trees and increase the yield. So the purpose of this study is determine the appropriate rate of vermicompost and organic matters to have the best yield of pomegranate fruits and to improve its physical and chemical characteristics. The present research has been made during two seasons (2020 and 2021) in a private orchard located in El-Beheira governorate, Egypt, to examine the effect of soil application of vermicompost at a rate of 1:5 kg/tree and organic matters at a rate of 5:10 kg/tree on productivity, physical and chemical properties of fruits and leaf minerals content of H116 pomegranate trees. The addition of vermicompost and organic matters in different rates were able to effect on leaves mineral content, fruits yield, fruit physical and chemical characteristics of H116 cultivar, compared with the treated trees with organic matter only. Moreover, soil application H116 cultivar with 2 kg vermicompost + 8 kg organic (T2) and 5 kg vermicompost + 5 kg organic matter were the best treatment in this study to gave the highest leaf minerals content, fruits yield and fruit physical and chemical characteristics and antioxidant activity in the 1st and 2nd seasons, respectively.
The Effect Of Elite Athletes' Club Environment Communication Levels On Sportsman Behavior
Authors: Dr. Seydi Karakuş , Sultan Yavuz Eroğlu , Dr. Cüneyt Aksak
Published: December 2022

The aim of this research is to determine whether the in-club communications of elite athletes in different sports can predict their sportsmanship behaviors. The study group of the research consists of 145 athletes (51.7% male, 48.3% female) randomly selected in athlete training centers and TOHM centers. The club media communication levels of the athletes were measured with the 3D (trainer-athlete, athlete-athlete and manager-athlete) Club Environment Communication Questionnaire. Sportsmanship Behaviors, on the other hand, were measured with the Multidimensional Sportsmanship Orientation Scale, which had 4 dimensions (compliance with social norms, respect for rules and management, commitment to responsibilities in sports and respect for the opponent). While analyzing the data, multiple linear regression analysis technique was used. In the results of the research, it is seen that there are positive (linear) relations between the Scores of the Club Environment Communication and Sportsmanship Orientation Subscales. In addition, it was seen that the communication between the coach and the athlete significantly predicted the dimensions of compliance with social norms and respect for the opponent, and the communication between the athlete and the athlete significantly predicted the sub-dimension of commitment to responsibilities. The result of the study reveals that as the scores obtained from each of the sub-dimensions of club environment communication increase, the scores obtained from each of the sub-dimensions of sportsmanship orientation increase reciprocally.
PRIMARY SCHOOL CURRICULUM AND IMPACT ON COGNITIVE LEARNING – A REVIEW BASED ANALYSIS
Authors: Mohita Bhardwaj , Dr. Deepti Dabas Hazarika
Published: December 2022

Objective: During initial phases of a child's life, there are 4 main areas of development: motor, communication, social/emotional and cognitive (thinking ability, knowledge, skill, and activities related to brain). We aim to study the primary school curriculum and its impact on the cognitive learning/development.

Methodology: Piaget's theory is one of the theories of paramount importance, while we discuss on cognitive development in the children.Huitt and Hummel (2003) studied the implications of this theory that segregates cognitive development into 4 stages namely 1. Sensorimotor stage 2. Pre-operational stage 3. Concrete operational stage, and 4. Formal operational stage.

Marwaha et al. (2017) studied the implication of Piaget's theory in children and their correlation with IQ. Basis Piaget’s theory it is recommended that the student's abilities should be challenged by teachers, but they should not present a curriculum which is beyond the child's level as that can adversely impact the cognitive development of the child. The current study has been carried out by analyzing the secondary data available through various research papers to derive a correlation between primary school curriculum and child's cognitive development. We also studied the deficiencies of the current primary school curriculum in getting the desired cognitive impacts on children.

Results and Implications: The study will help understand the primary school curriculum in India, studying the impact of curriculum on cognitive development and identification of important factors/aspects in the curriculum ((content, teaching pedagogy etc).
TENDON ACTUATED MECHANISM BASED ROBOTIC PROSTHETIC HAND DESIGN FOR DEXTEROUS MANIPULATION AND GRASPING
Authors: Deepak Ranjan Biswal , Pramod Kumar Parida
Published: December 2022

In Robotic hand designit’sapronounced challenge to afford a robotic arrangement with dexterous aptitude and independent skilfulness particularly in the field of prosthesis, Industrial manufacturing, orthopaedic rehabilitation etc. Avery high diverse level of actuation and transmission scheme is requisite for a multi-fingered robotic hand to accomplish its manoeuvre. The under actuation concept become an encouraging way out to obtain robotic hands with high dexterity without additional complex mechanical design. The foremost feature of an under actuated robotic hand is that the total actuators required to function the hand is fewer than its movability or degree of freedom. The Under actuation decreases impressively the complication of the control system and is less expensive than the fully actuated equivalent hand. The hand is also lighter that it’s fully actuated equivalent. The current work proposed with the design and Kinetostatic analysis of a five-fingered robotic hand in which four under actuated fingers and an under actuated thumb with dexterity is present with a whole of twenty one Degrees of freedom and twelve numbers degree of actuation
ANTIDIABETIC ACTIVITY Symplocos racemosa (LODHRA) AND Cinnamon cassia (CINNAMON BARK) FORMULATION SYNTHESISED SILVER NANOPARTICLES
Authors: Sneka S , Anju Cecil , S. Rajeshkumar
Published: December 2022

Aim: The  aim of this study is to analyze the anti-diabetic effect of silver nanoparticles using symplocos racemosa( lodhra) and cinnamomum cassia ( cinnamon bark ) assister silver nano particle.

Introduction: Lodhra is widely used in various Ayurvedic medicines. Cinnamon is one of the most important spices used daily by people all over the world.Nanoparticles have been used in various practical applications. Silver nanoparticles (AgNPs) are increasingly used in various field.Recently, AgNPs have been frequently used in many Silver nanoparticles (AgNPs) have been successfully applied in several areas due to their significant antimicrobial activity against several microorganisms. In dentistry, AgNP can be applied in disinfection, prophylaxis, and prevention of infections in the oral cavity.

Materials and methods: Fresh lodhra bark and cinnamon powder was collected. 1g of freshly collected Lodhra and cinnamon bark extract is mixed with 100 ml of distilled water thoroughly and boiled for 3-5 mins in a heating mantle then filtered by using filter paper. Silver Nitrate powder is added in 500 ml of distilled water and to this lodhra bark extract has been added. The solution is kept in a shaker and the reading was taken for every 2 hrs for analyzing the synthesis of nanoparticles. The reaction was initiated by the addition of 490, 470, and 450 μl buffer to different volumes (10, 30, and 50 μl) of 30mg/mL of Lodhra and cinnamon bark extract, synthesised silver nanoparticles, stored (at 37°C and 4°C), and calcined (300°C, 500°C and 700°C) AgNPs samples, respectively, to make the total volume of 500 μl reaction solution.

Results: Antidiabetic activity of lodhra and cinnamon bark extract mediated AgNPs  was assessed using alpha amylase assay. In this silver nanoparticles induced Lodhra and cinnamon bark extract shows more antidiabetic activity than the herbal extract

Conclusion: From this it is concluded that Lodha and cinnamon bark shows significant anti diabetic activity. Also this extract can be used in toothpaste & mouthwash to reduce the inflammation in oral cavity. Further studies can be done on the side effects of Lodha and cinnamon bark using silver nanoparticles and also on the other activities of  Lodha and cinnamon to know it’s complete potential
TEACHER'S STRATEGY IN DISCIPLINE ON STUDENT LEARNING ONLINE IN THE COVID-19 PANDEMIC (CASE STUDY AT SDN 01 IWUL, SDN 02 IWUL, SDN 03 IWUL, PARUNG DISTRICT, BOGOR)
Authors: M. Givi Efgivia , R. Andi ahmad Gunadi , Al-Bahra
Published: December 2022

Discipline of students in the teaching and learning process is very important to support the suSDN 01 Iwul, SDN 02 Iwul, SDN 03 Iwuless of the teaching and learning process in the classroom during the COVID-19 pandemic. However, many students lack discipline when participating in the teaching and learning process during the COVID-19 pandemic, such as being late for a Zoom class, turning off the camera unilaterally for various reasons, and turning off the sound when asked to participate for technical reasons. This study aims to find out a clear picture of the teacher's strategy in disciplining student learning online during the Covid-19 pandemic at SDN 01 Iwul, SDN 02 Iwul, and SDN 03 Iwul. The approach in this study is a qualitative approach, the method used is a descriptive method. Sources of data used in this study is primary data. Primary data were obtained from the answers to interviews conducted with key informants who were designated as research samples. The result of this study is that student discipline in the implementation of online learning during the Covid-19 pandemic at SDN 01 Iwul, SDN 02 Iwul, and SDN 03 Iwul is quite good. Teachers teach based on lesson plans and syllabus and teach with mixed methods (blended learning) using whats up group applications, google class rooms, and google meet in learning. The teacher's strategy in disciplining student learning online is by making learning contracts, providing understanding material about discipline with the narrative method. And being an example by always being on time, besides that, the teacher always gives assignments to get students to be disciplined in learning. The obstacles that oSDN 01 Iwul, SDN 02 Iwul, SDN 03 Iwulur after the student discipline strategy is implemented are that there are still students who do not do assignments on time, student participation in conveying arguments or opinions is still low so that learning runs monotonously. In addition, students often commit plagiarism in completing their assignments. The efforts made are by always advising and providing an understanding of the importance of discipline and providing good examples and examples to students. Create groups, so that students are more active in learning because they have to present and discuss. The next step, if three times the student is reprimanded, the student is not also present in the online class and does not collect assignments, then the teacher asks the homeroom teacher and BK teacher for help to reprimand the student.
Registration Of Neurological Patiens In Primary Healthe Care
Authors: Babadjanova Zamira Xikmatovna
Published: December 2022

The affectiveness of  dispensary records has been studied by examining ambulance records of 460 patients with chronical illnesses. The following results has been defined: recovered 2.1%, satisfactory 70.2%, stabile 2,2%,disability 4.5%,the illness got worse 2.5%.
Nervous System Damage During Herpes Viral Infection
Authors: Artikova Mavluda Abdurakhmanovna , Safarov Samad Sadikovich
Published: December 2022

Herpes is one of the most common uncontrolled human viral infections. Despite the fact that herpes has been known for more than 2000 years, only in the last decade has a real possibility of organizing effective herpes therapy appeared. Some infected individuals may have mild symptoms in the form of fever, adenopathy, or general infectious manifestations. Usually, HSV1 infection is not epidemic and occurs sporadically. In 20-40% of persons infected with HSV1, its spontaneous reactivation is observed in the form of rashes on the face.
Combining Machine Learning Mechanism With Statistical Models For Predicting The Survival Of Lung Cancer
Authors: Udara Rangana Jayathilaka , Gi-Cheon Park
Published: December 2022

Machine learning is a great artificial intelligence technology used in cancer prediction and diagnosis. Also, with the development of personalized and medical applications, there has recently been a rising tendency to machine learning (ML) techniques for prognostic predictions. However, developing accurate prediction systems of cancer mortality in medical environments remains a challenge.A regression model is being constructed to forecast lung cancer individuals' survival rates in months. It has previously been demonstrated that predictive analytics function well for brief overall survival of lower than 6 months; nevertheless, model performance decreases as greater survival times are attempted to be predicted. To estimate survival rates, regression systems are proposed in conjunction using a classification framework for this research. The Surveillance, Epidemiological, and End Results (SEER) dataset were used to gather a collection of de-identified lung cancer survivor data. To evaluate lung cancer information from the SEER study to construct effective lung cancer survival predictive design. Several qualities were removed/modified/split as a consequence of specially planned pre-processing processes, and two of the 11 resultant characteristics were shown to offer substantial predictive potential.ANOVA is used to choose a subset of components for the analyses. For classifying, a confusion matrix is used, and for regression, the Root Mean Square Error (RMSE) is used.For classifications, Random Forests (RF) were utilized, whereas, for regression, conventional Regression Analysis, Gradient Boosted Machines (GBM), and Random Forests have been used. The regression findings indicate that RF performs better for survival periods of  and  months on RMSE  and , correspondingly, whereas GBM was quiet for survival periods of  months on RMSE . Results comparison charts show that its regression analysis functions stronger for median survival durations than the RMSE estimates can reflect.
STEP TOWORDS THE FORMULATION OF INJECTABLE HYDROGEL: PREFORMULATION STUDIES OF TERIFLUNOMIDE
Authors: Phalke Pallavi L , Dr. Patel Dipti H
Published: December 2022

Purpose: The aim of formulation of this hydrogel is to treat the osteoarthritis which is one of the common inflammatory autoimmune disorders of joints. The use of conventional drugs like NSAIDs having various side effects.

The aim of our research was to develop a formulation of injectable hydrogel containing teriflunomide. This study will be helps us for the development of stable, robust and therapeutically effective dosage form.

Method: Solubility of Teriflunomaide was determined by using various solvents. By using infrared spectrum and  absorption maxima the purity of sample was checked. With the help of UV spectrophotometer standard UV curve was developed. Drug excipients compatibility studies were performed using Fourier transform infrared spectroscopy, differential scanning colorimetry, partition coefficient and also short term drug solution stability studies were performed.

Result: Teriflunomide is soluble in methanol & 0.1 N NaOH on the other hand poorly soluble in distilled water, phosphate buffer (pH 7.4) and 0.1 N HCl. Absorption maxima was observed at 292nm and infrared spectrum was showing the characteristic peaks.  The standard curve obtained was linear with correlation coefficient below 1. Log P value obtained at 2.78 it confirms that teriflunomide is having both hydrophilic & hydrophobic nature.  After the entire short term stability studies drug was found to be stable in short term stability studies.

Conclusion: The studies like melting point, FTIR etc suggested that drug selected for the formulation was found to be pure. Partition coefficient values suggested that it is having both hydrophilic and hydrophobic nature. Results obtained from short term stability studies were suggested that drug is stable showing no degradation on phosphate buffer which confirmed by no shift of  λ max.
Comparison Of Pap Smear With Visual Inspection With Acetic Acid In Screening Of Carcinoma Cervix
Authors: Savitha Keranahalli Basanna , Charita U , Anuradha S N
Published: December 2022

Background: Cervical cancer is the second most common among women globally. In most cases of  Ca Cervix is detected late due to lack of effective screening programme.

 

Aim: Present aim is to detecting the efficacy of visual inspection of cervix with acetic acid with Pap smear in early detection of carcinoma of cervix.

Materials and methods:  The cross sectional study conducted in 100 women attending GYN OPD were included in the study. They were screened with Pap smear and VIA, those positive with either of the method were subjected to biopsy. The sensitivity, specificity, PPV and NPV were calculated using biopsy report as the reference standard.

Results: The mean age of the study subjects and those with screen positivity were 39.04 yrs and 39.96yrs respectively. Multipara constituted majority of the screened positive cases. Among the study group, white discharge was the predominant complaint. Cervix was clinically healthy in (45%) of the patients and unhealthy in rest of the patients. 21.4 %( 3 out of14) of the cases having healthy cervix on examination had dysplasia. VIA was positive in all the 3 cases and Pap smear was positive in only one case. 25% of the patients had positive VIA. 29% of the patients had mild dysplasia, 16.1% of the patients had moderate and severe dysplasia. Pap smear missed 5 cases of dysplasia and VIA missed 1 case of dysplasia. The VIA sensitivity-92.8%, specificity-29.4%,  PPV-52% and  NPV-83%. In pap smear sensitivity-64.2%, specificity-76.4%,  PPV-69.2% and  NPV-72.2% respectively.

Conclusions: Thus VIA was more sensitive than cytology. Whereas Pap smear was more specific.