bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans
Authors: Stogios Peter J , Liston Sean D , Semper Cameron , Quade Bradley , Michalska Karolina , Evdokimova Elena , Ram Shane , Otwinowski Zbyszek , Borek Dominika , Cowen Leah E , Savchenko Alexei
Published: May 2022

In the human fungal pathogen Candida albicans, ARO1 encodes an essential multi-enzyme that catalyses consecutive steps in the shikimate pathway for biosynthesis of chorismate, a precursor to folate and the aromatic amino acids. We obtained the first molecular image of C. albicans Aro1 that reveals the architecture of all five enzymatic domains and their arrangement in the context of the full-length protein. Aro1 forms a flexible dimer allowing relative autonomy of enzymatic function of the individual domains. Our activity and in cellulo data suggest that only four of Aro1’s enzymatic domains are functional and essential for viability of C. albicans, whereas the 3-dehydroquinate dehydratase (DHQase) domain is inactive because of active site substitutions. We further demonstrate that in C. albicans, the type II DHQase Dqd1 can compensate for the inactive DHQase domain of Aro1, suggesting an unrecognized essential role for this enzyme in shikimate biosynthesis. In contrast, in Candida glabrata and Candida parapsilosis, which do not encode a Dqd1 homolog, Aro1 DHQase domains are enzymatically active, highlighting diversity across Candida species.
Surveys of Professionals
Authors: Clements Michael P. , Rich Robert W. , Tracy Joseph S.
Published: May 2022

This chapter provides an overview of surveys of professional forecasters, with a focus on the U.S. Survey of Professional Forecasters and the European Central Bank Survey of Professional Forecasters. A distinguishing feature of these surveys is that they collect point and density forecasts and make the data publicly available. We discuss their structure, issues involved in using the data, and the construction of measures such as disagreement and uncertainty at the aggregate and individual levels. Our review also summarizes the findings of studies exploring issues such as the alignment of point forecasts with measures of central tendency from associated density forecasts, the coverage of density forecasts, the rounding of point and density forecasts, comparisons of forecast accuracy across respondents, and heterogeneity in forecast behavior and the persistence of these differential features. We conclude with some observations for future work.
The addition of lactic acid bacteria in the soybean soaking process of tempeh
Authors: Magdalena S. , Hogaputri J.E. , Yulandi A. , Yogiara Y.
Published: May 2022

Soaking is one of the important steps in tempeh production. Various microorganisms grow
during the soaking process, which can affect the nutrition and quality of the tempeh. This
study aimed to determine the effect of adding lactic acid bacteria (LAB) to the soaking
process and determined the preference levels of the produced tempeh. In this research,
Lactobacillus plantarum HPADA3 and Lactobacillus fermentum HPBD2 were added
during the soaking of the soybeans. Each LAB had been evaluated for its hemolytic
activity and potential virulence factor genes. The soaking duration was much shorter than
was commonly done for tempeh production. The resulting tempeh was observed from
their appearance and then underwent a sensory evaluation test. It was found that the
shorter duration of soaking resulted in compact tempeh. The addition of LAB did not
affect the fungal growth in tempeh fermentation. Overall, the bacteria population observed
on agar media from the water and tempeh samples were significantly different. All
produced tempeh was liked from an evaluation from semi-trained panellists. From all the
tempeh variants, the tempeh with the addition of Lactobacillus fermentum HPBD2 was
perceived as the most likeable and similar to commercial tempeh.
RANGE OF LAWN GRASSES AND THE STATE OF LAWNS IN THE LANDSCAPING FACILITIES OF STAVROPOL
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, GRECHUSHKINA-SUKHORUKOVA L.A.
Published: May 2022

In 2019–2021, a study of the species composition and current state of ornamental lawns in two parks, a boulevard and ten public gardens in Stavropol was conducted to evaluate the range of lawns used, their current state and to determine the effectiveness of the management measures taken to improve the quality of lawn coverings. The collected database can be used to make effective economic decisions to optimize the range and increase the ecological and aesthetic value of landscaping objects. The longevity of a lawn depends on the selection of lawn formers adapted to the given soil and climate conditions, capable of producing a high-quality lawn for many years and on proper care. The survey found that lawn grasses of the first and second quality groups were mainly used to create lawn coverings – Poa pratensis L., Festuca rubra L., Lolium perenne L., with Trifolium repens L. subseeds. In most cases, grass mixtures were used to create lawns. Recently, a more drought-resistant species, Festuca arundinacea Schreb, has been used more often as a lawn-forming agent. Most of the surveyed grass stands were rated “satisfactory” and “good” lawn. Stationary irrigation systems have been installed in a number of new landscaping facilities; rolled lawns have been used more often. Among the factors of negative impact on non-irrigated lawns are long dry periods, which led to the burning of lawn grass up to II–IV points, in 2018 – more than 50 days, in 2019 – more than 40 days, in 2020 – more than 60 days. At the same time, they lost their decorative, environmental and sanitary functions. Another negative environmental factor was the shading of lawns by tree crowns, which leads to thinning of the herbage, loss of decorative effect and the formation of dead covers. Additional shading of the lawn grasses was provided by leaf litter which was not removed in time. Almost all lawns had weed species that increased in number with age (clogging 1–3 points, abundance r-3). As a rule, mowing lawns did not destroy perennial weeds, the renewal zones of which were below the cut-off level of the lawn mower. No insect and disease damage to plants was detected. Negative anthropogenic disturbances on the surveyed landscaping objects are trampling, laying trails, dog walking. Lawns are regularly seeded and repaired.
RESULTS OF EVALUATION OF SPRING SOFT WHEAT VARIETIES OF VARIOUS AGRO-ECOTYPES BASED ON DROUGHT RESISTANCE AND DONOR PROPERTIES
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, VOLKOVA L.V. , AMUNOVA O.S.
Published: May 2022

For spring wheat, it is extremely relevant to study drought resistance in the initial phases of the growing season, as water deficiency during this period leads to significant yield losses. The method of seed germination in distilled water (control) and sucrose solution (experiment) makes it possible to evaluate drought resistance by morphological characteristics in the seedling phase. The studied varieties of spring wheat belonging to different ecotypes significantly differed in the number of germinal roots, total seedling biomass, redistribution of plastic substances between root and the general combining ability (GCA). The Nos Norko variety (Germany) had a significantly high number of germinal roots in the control (109% of the group average) and a consistently high OCS in the series of generations, which allows it to be classified as a donor of this trait. The Klein Vencedor variety (Argentina) had the highest seedling weight (112…120%) in the control and experimental variants. This genotype was also characterized by a relatively low stress response. The resulting hybrids differed in their seedling weight in the second and third generations. The RSR diagnostic method makes it possible to clearly differentiate the studied varieties by adaptive drought resistance strategy. The Jahuara F-77 (Mexico) and Karabalykskaya 91 (Kazakhstan) varieties redistributed most of the plastic substances in the roots under water shortage, the Nos Norko (Germany) and Erythrospermum 1129 (Russia) varieties maintained a stable root/sprout ratio. The inclusion of selected varieties in the crossing program will produce hybrids with maximum genetic diversity and expanded amplitude of possible adaptation to changes in the hydrothermal regime. In practical work, when analyzing breeding material under control conditions, it is important to note that genotypes with a large number of roots were characterized by good donor properties of this trait. Under stress conditions, genotypes with a large number of germinal roots had an increased seedling biomass and increased root/sprout ratio. The heritability of the studied traits indicates that the selection efficiency may be higher in terms of the number of roots and RSR in the control, and in terms of seedling weight in the experiment.
Carbonia 1937- 41. The Worksite of Autarchic Architecture
Authors: Sanna Antonello , Monni Giuseppina , Sanjust Paolo
Published: May 2022

Carbonia is one of the examples of Italian autarchy before the beginning of World War II. Some of the main national construction companies and high-level designers, of which came from the previous experiences of Fascist foundation towns, focused on the new capital of the coal district. Carbonia is the last phase of this experiment, the most important in terms of size and strategic relevance.
Carbonia’s urban scene is clearly characterized by two dominant approaches: Pulitzer’s central European modernism, which features the “First Carbonia”, and Montuori’s Mediterranean rationalism, which features the next phase of the “Great Carbonia”. Peripherality and lack of infrastructure, lack of supplies and delays in procurement, unavailability of manpower, and technical adjustments due to unforeseen events constant afflict the emergency autarchy construction site.
And while the Great Serbariu mine concentrates cutting-edge technologies at an international level, the company town continues to be built in conditions of extreme cost containment. The two parallel construction sites express technological osmosis and the driving role of innovation that the mine yard exercises over that of the city. Our long-term work commitment to reconstructing the history of the autarchic building sites through archival and field research, also documents the refined strategies of some of the most important designers of that period. They adapted their working methods to lead the process towards a unitary and high-quality outcome.
Structure and properties of rapidly solidified foils of triple Bi – In – Sn alloy and solder joint based on it
Authors:   Belorusian State University, Shepelevich V. G. , Gusakova O. V. ,   Belorusian State University, Husakova S. V. ,   Belorusian State University
Published: May 2022

The alloy Bi32In41Sn27 was produced by fusing the components in quarts ampoules. A piece of alloy of 0.2 g was heated and injected onto the inner polished surface of rapidly rotating copper cylinder with a diameter 20 cm. The alloy was solidified in the form of a foil up10 cm long and up to10 mm wide. Foils with a thickness of 30 – 100 micrometers were used for the study. The chemical compositions of the foil in the layers in contact with surface of the mold and the atmosphere are coincided within the measurement error. A rapidly solidified alloy Bi32In41Sn27 consists of ε-phase (BiIn) and γ-phase (Sn4In) having a dispersed structure. The average value of the chords dγ of random secants located on the sections of γ-phase and average value of the specific surface area of the interphase boundary Sε – γ, formed by ε- and γ-phases, depend on the expose time t at room temperature; their properties are described by equations d = 0,58 + 0,29lnt and Sε – γ = 2,9 − 0,43lnt, correspondly. The alloy foils have a microcrystalline structure and well-defined texture (0001) of the γ-phase and poorly expressed double (211) + (112) of the ε-phase. Texture are persist during annealing 60 °С for 2 hours. The microhardness of the alloy Bi32In41Sn27 foils monotonically increases with increasing expose time at room temperature and reaches saturation. Subsequent isothermal annealing at 60 °С leads to a microhardness value equal to it of massive sample. The distribution of components in the solder joint between copper plates was investigated. Indium and tin diffuse into the copper plates. The depth of penetration of copper into the joint reaches 3 micrometers. When the soldered copper plates are strained, the breakdown on the junction occurs at 790  N and absolute value of the deformation is 0.8 mm. The conducted investigations of copper solder joints indicate the possible practical use of the alloy Bi32In41Sn27 foil as a solder.
Housing Environment Affects Pubertal Onset, Anxiety-like Behavior, and Object Interaction in Male and Female Long Evans Rats
Authors: Vogt Meghan E , Riesgo Victoria R , Flanigan Kaylyn A S , Willing Jari G
Published: May 2022

Rodents used for research can be humanely housed in a variety of ways. As such, a vast number of different housing environments are used, but are often not described in research publications. However, many elements of housing environments, including bedding, diet, water bottles, and
cage material, can expose rodents to natural and synthetic compounds that can have lasting effects on the body, brain, and behavior. Some environmental items contain endocrine-disrupting compounds (EDCs), which can affect many commonly assessed physiological and behavioral endpoints in rodents.
Here, we compare the effects of 2 commonly used housing environments for male and female Long Evans rats on body weight, pubertal onset, and a battery of behavioral tests measuring activity, anxiety-like behavior, and cognition. One standard environment was comparatively high in EDCs (standard
rodent chow, plastic cages, plastic water bottles, and corncob bedding), while the other was a relatively low-EDC environment (phytoestrogen-free chow, polysulfone cages, glass water bottles, and wood-chip bedding). As compared with the Standard group, rats raised in the Low-EDC environment
reached puberty earlier, displayed less anxiety-like behavior in the elevated plus maze and open field test, and showed less overall object exploration in the novel object recognition task. These effects occurred only if rats had been raised in these conditions since conception. An acute change
from one environment to the other in adulthood did not yield these same effects. These results provide further evidence for the effects of common housing environments on development and behavior and highlight the importance of reporting environmental conditions in the literature to promote
reproducibility in research using animal subjects.
Structuring of Problematic Situations in Teachers’ Activities When Organising Physical Education in Inclusive Conditions
Authors: Kleimenova Marina Nikolaevna , Timofeeva Elena Viktorovna , Kosacheva Tatiana Alexandrovna , Sheenko Evgeny Ivanovich , Bakhmutskaya Yulia Anatolyevna
Published: May 2022

The purpose of the study is to characterise problematic situations and difficulties arising in the process of physical education implemented by specialists in the field of physical education in inclusive conditions, at the same time substantiating specific ways to prevent these difficulties. The paper presents an analysis of Russian and foreign sources concerning the issues of training and retraining of pedagogical personnel in the field of physical education and also identifies the problems and difficulties faced by physical education specialists in inclusive conditions. Scientific novelty of the study lies in systematising problematic situations and difficulties encountered by physical education teachers in inclusive practice, based on which specific recommendations for the training of future physical education teachers capable of working in an inclusive environment are proposed. As a result, the researchers have substantiated a list of necessary measures contributing to the formation of inclusive practice readiness in future physical education teachers.
Theoretical Aspects of Genre Competence Formation in Cadets When Teaching Russian as a Foreign Language (Commanding Profile)
Authors: Goncharova Maria Valerievna
Published: May 2022

The study aims to substantiate the relevance of genre competence formation in foreign cadets when teaching the Russian language as a component of communicative competence in educational and professional communication. The paper considers the requirements of the Federal State Education Standard and the demand of the leading departments of the university when determining the relevant communicative needs of foreign cadets, analyses the available educational materials in Russian as a Foreign Language, taking into account military specifics. The genre organisation of formal military communication, universality and relevance of these genres for students of military universities are demonstrated, genre and linguistic features of formal texts of military communication are described. Scientific novelty of the study lies in substantiating the importance of the genre approach, taking into account genre standardisation of formal military communication when teaching Russian to foreign military personnel (hereinafter - FMP) for purposes of genre competence formation. As a result, the researcher has proved that a system of formal style genres, the genre particularities of which include the presence of a certain communicative goal, a strict structure and a number of fixed lexical and grammatical features, is relevant for teaching foreign cadets. This system of texts, with its genre nature and implementation within the framework of the official style, comprehensively and succinctly reflects the linguistic features of the military educational and professional discourse, which makes it possible to develop a model of military communication to the extent necessary for foreign cadets, based on the didactic principles of Russian as a foreign language teaching.
Issue of Studying Semantic Reading in Students with Health Limitations in the Context of Education Digitalisation: A Theoretical Review
Authors: Ivleva Mariya Gennad’evna , Lopatina Ludmila Vladimirovna
Published: May 2022

The paper aims to provide an overview of modern Russian and foreign theoretical and experimental sources on the study of semantic reading among students with health limitations in the setting of education digitalisation. The paper analyses the changes in the field of educational texts in the conditions of education digitalisation, presents an analysis of the results of modern research on semantic reading among students with health limitations, as well as a theoretical justification for the need to modify diagnostic tools for the study of semantic reading in schoolchildren with health limitations. Scientific novelty lies in carrying out a comprehensive analysis of the little-studied issue of perception and comprehension of texts of various types and formats in the process of reading by students with health limitations. As a result, it has been found that it is important for correctional pedagogy to update the tools for diagnostic assessment and elimination of difficulties in semantic reading, taking into account the conceptual modifications of the educational and methodological material used in teaching.
Effort of Studying Inspiration and Associated Emotional Experiences in the Creative Activities of Student Youth
Authors: Starikov Pavel Anatolievich
Published: May 2022

The purpose of the research is to identify the interrelationships between various aspects of manifestations of inspiration in the creative activities of university students (emotional experiences associated with inspiration, characteristic features of the state of inspiration, semantic associations related to inspiration, areas of creative activities), using the example of students of the Siberian Federal University. The paper considers the results of a study of university students conducted by means of a questionnaire survey on a sample of 450 people, discusses the experience of using indicators and data analysis techniques. Scientific novelty of the research lies in developing tools for studying manifestations of inspiration in students involving methods of multivariate statistics. As a result, the researcher shows the possibility of using multidimensional scaling for a qualitative study of the structure of students’ emotional experiences. A cluster of positive emotional experiences associated with the state of inspiration has been identified. An index indicator for the degree of expression of the characteristics of inspiration in students’ creative activities has been proposed. The interrelationship between the degree of manifestation, expression of the characteristics of inspiration in students’ creative activities and their positive emotional experiences, various areas of creative activities has been determined. The proposed indicators and methods of analysing the results can be used to study and monitor the creative activities of university students. The identified structural patterns associated with the state of inspiration expand the understanding of the psychotechnical and pedagogical possibilities of the creative process.
Analysing Foreign Design Education (by the Example of Western Europe, the USA and China)
Authors: Kuvshinova Galina Anatolevna
Published: May 2022

The purpose of the study is to provide insight into the range of issues related to the quality of foreign design education, its advantages and systematicity, using the example of Western Europe, the USA and China. The paper gives a brief overview of the historical development of foreign design education over the period from the early XX century to the present day. Scientific novelty of the work lies in identifying the main advantage of foreign design education, i.e. the integration of design education in most developed countries and regional economies, close cooperation with public institutions. As a result, the researcher has concluded that foreign design education is aimed at solving practical tasks, forming project thinking in future designers and is implemented in relation to the needs of local and regional markets.
Features of Teaching Chinese Watercolour Techniques to Chinese Students - Future Teachers of Fine Arts en Plein Air
Authors: Chang Hongbin
Published: May 2022

The study aims to determine the features of teaching traditional Chinese watercolour painting during the training of future teachers of fine arts in plein air practice in higher education institutions of the People’s Republic of China. The paper analyses the main genres, styles, techniques of Chinese painting used in plein air work in watercolours by students. Scientific novelty lies in identifying the features of Chinese watercolour techniques employed in plein air practice when teaching students. The use of problem-based learning technology makes it possible to form professional skills in future teachers of fine arts when working in watercolours, preserving the continuity of Chinese fine art traditions. As a result, it has been shown that the teaching of Chinese watercolour techniques en plein air contributes to the formation of professional artistic knowledge, skills and abilities in future teachers of fine arts in Chinese national traditions.
A transição da educação infantil ao ensino fundamental: considerações sobre o ensino da linguagem oral e escrita
Authors: Carvalho Bruna
Published: May 2022

Neste artigo, nosso foco é a transição da educação infantil ao ensino fundamental. Objetivamos tecer considerações sobre o ensino da linguagem oral e escrita na educação infantil e no 1º ano do ensino fundamental, visando garantir uma continuidade do processo de ensino e aprendizagem. Para tanto, adotamos os seguintes procedimentos: explanação do conceito de atividade e principais características da periodização do desenvolvimento humano na psicologia histórico-cultural, em especial, o desenvolvimento da criança de 4 a 6 anos; por fim, tecemos algumas considerações a respeito da organização do ensino no último ano da educação infantil e no 1º ano do ensino fundamental para que ocorra de fato uma transição, e não um rompimento, no processo de ensino e aprendizagem da linguagem oral e escrita.
Dificuldades e desafios dos professores do ensino fundamental 1 em relação ao ensino de ciências
Authors: Ribeiro Sidélia , Welter Adams Fernanda , Maria Tavares Nunes Simara
Published: May 2022

O Ensino de Ciências é de suma importância na formação cidadã; desde que este seja planejado, pode possibilitar uma compreensão do mundo, ou seja, promove uma leitura do mundo. Entretanto são vários desafios para que a formação cidadã ocorra e um dos desafios é a formação inicial dos professores no Ensino de Ciências. Vários autores têm discutido as dificuldades dos professores do Ensino Fundamental 1 nesta área de conhecimento. Assim, o presente artigo tem como objetivo apresentar um recorte de um Trabalho de Conclusão de Curso no qual abordamos as dificuldades e desafios enfrentados pelos docentes do Ensino Fundamental 1 no exercício de sua ação pedagógica no Ensino de Ciências em uma escola da rede pública do interior do estado de Goiás.  Para o desenvolvimento desta pesquisa utilizou-se para coleta de dados questionários com perguntas abertas e fechadas, que foram respondidos por oito professores das turmas de 1º ao 5º ano da Escola. Os dados obtidos através dos questionários foram transcritos e analisados de acordo com a Análise Textual Discursiva.  Avalia-se que os professores reconhecem a importância do Ensino de Ciências para a formação dos alunos. Porém, apontam uma série de dificuldades como falta de tempo devido à cobrança sobre Português e Matemática, a falta de recursos didáticos e por fim, a falta de formação inicial adequada. Acredita-se que a oferta de uma formação continuada poderia auxiliar a mudar a realidade do Ensino de Ciências no Ensino Fundamental 1.
Drivers of crop impacts from tephra fallout
Authors: Ligot Noa , Guevara Alicia , Delmelle Pierre
Published: May 2022

Agriculture is an economic and social pillar for the least developed countries. When these regions host volcanoes that exhibit explosive behaviour, a serious risk for agricultural production arises as crops endure various impacts from tephra fall. In order to gain new insights into the factors that govern tephra impacts on crops, we collected farmers’ perceptions of crop damage and production loss due to exposure to tephra fallout in 15 villages affected by the 1999–2014 eruptions of Tungurahua volcano, Ecuador. Crop type and developmental stage - both influenced by altitude - strongly modulate the level of tephra-induced impact. Using these observations, we illustrate how crop vulnerability fluctuates spatially and temporarily in the surveyed area. The study also highlights that fine tephra (<63μm) is more harmful to crops than coarser particles. Farmers have responded to the tephra hazard by favouring crops more resistant to tephra, a practice that has reduced crop diversity.
Possibilities for single-round ensuring of parts contact rigidity at the design stage
Authors: Suslov Anatoliy , Khandozhko Viktor
Published: May 2022

Theoretical dependences of the contact rigidity of parts at the design stage on machining conditions of joint surfaces are given. Technological methods of machining for ensuring contact rigidity are provided. Methodology and sample calculations of operating modes with the choice of the optimal working method are viewed.
Study of negative hardening effect on the properties and structure of the catalytic carrier based on a Ni-Al-Al2O3 system on a metal substrate obtained by cold gas dynamic coating
Authors: Yakovleva Nadezhda , Farmakovsky Boris , Makarov Alexander , Staritsyn Mikhail
Published: May 2022

The study of the effect of baseline purvulent composition formulation on the specific surface area and changes in the microtexture, phase composition and thickness of coatings when healed, is described.
Translation Ethics: An Investigation into Lady Welby’s Upward Translation from the Perspective of Meaning Triad
Authors:   Shinawatra University, Thailand, Gao Fan , Dechsubha Thawascha
Published: May 2022

This paper offers a comprehensive survey of translation ethics within the theoretical frame of Lady Welby’s meaning triad concerning the relationship between ethics and translation in the meaning process of sign activities. The paper mainly discusses such aspects as: (1) the relationship between meaning triad and translation ethics, (2) upward translation as a method to maximize ethical value and (3) enhancement of translation ethics as a goal of upward translation. The results of the paper can be found as the following: 1. the evolutionary process of meaning from sense to meaning and then to significance is the path for the improvement of translators’ cognitive ability and the sublimation of translator or interpreter’s ethics and morality. 2. Upward translation serves as a key to enhancing translators’ ethical consciousness.3. translation, meaning and ethics are correlated and interrelated mechanisms. Therefore, the implications of the dynamic and dialogic view of translation and meaning will provide an interdisciplinary theoretical vision for the construction of translation ethics.
The Effect of the Phenomenon of Phubbing on the Organizational Behavior of Administrators Working in Vocational Education Schools in The Light of the Variables of Appreciation and Provision of Attention to Employees
Authors:   Mutah University, Ministry of Education, Al-Baher Ibrahim Ali , Mohammad Israa Abdallah , Shaile Maysoon Mahmoud , Alahali Ghadeer Ibrahim
Published: May 2022

The aim of this research is to identify the effect of the phenomenon of Phubbing on the organizational behavior of administrators working in vocational schools in the light of the variables of appreciation and Provision of Attention to Employees. The research community consisted of (45) administrators, who were selected in a stratified random manner. The descriptive survey method was used in the current research. To achieve the objectives of the research, a questionnaire was developed, and its validity and reliability were confirmed. The results showed that the effect of the phenomenon of Phubbing on the organizational behavior of administrators working in vocational education schools in the light of the variables of appreciation and concern for workers was medium. The results of the research also showed that there were statistically significant differences at the significance level (α ≤ 0.05) according to the gender variable in favor of the male category. And there were no statistically significant differences according to the educational qualification variable, and there were no statistically significant differences according to the years of experience variable. In light of these results, the research recommended that the administrations of vocational education schools attach great importance to organizational behavior And work on treating it and alleviating the obstacles it faces and trying to tackle the phenomenon of Phubbing, So that it works to stimulate conducting studies and research from time to time to find out the effects of this phenomenon on organizational behavior in various circumstances and organizational variables in the educational administrative environment.
Comparing and Evaluating Five-Day Chemotherapy Agents Actinomycin D and Methotrexate in Low-Risk Post-Molar Gestational Trophoblastic Neoplasia: A Retrospective Analysis
Authors: Xu Juan , Wang Xinmei , Qu Pengpeng
Published: May 2022

Background: Low-risk post-molar gestational trophoblastic neoplasia is sensitive to chemotherapy, but there is no consensus regarding the best treatment regimen for low-risk post-molar gestational trophoblastic neoplasia. This study aimed to assess the efficacy, toxicity and cost-effectiveness of actinomycin D and methotrexate in low-risk post-molar gestational trophoblastic neoplasia. Methods: 210 patients with Federation International of Gynecology and Obstetrics(FIGO)-defined low-risk post-molar gestational trophoblastic neoplasia received either a first-line five-day methotrexate intramuscular injection biweekly (MTX group) or a five-day actinomycin D infusion biweekly (Act-D group). Demographic information, disease manifestations, initial treatment plan, treatment-related adverse events, cost-effectiveness and the effects of drugs on ovarian function and quality of sexual life were recorded and retrospectively compared. Results: The complete response rates were 72.73% for the Act-D group and 75.41% for the MTX group, with no statistically significant difference. Compared to the Act-D group, the MTX group had a significantly shorter total number of chemotherapy cycles and average hospitalization expenses (p < 0.05). There was no severe adverse effect reported for either group, but the Act-D group was associated with significantly higher leukopenia (grade 1 or 2) (59.38% vs. 17.39%). The two regimens had reversible effects on ovarian function and quality of sexual life, but there was no significant difference between the two groups. Conclusions: There were similar complete response rates and no severe adverse effect reported for either group, but the total treatment course was shorter and the average hospitalization expenses were lower in the MTX group. Five-day MTX intramuscular biweekly injections remain the treatment of choice for patients with low-risk post-molar gestational trophoblastic neoplasia. Chemotherapy will have a certain impact on ovarian function. Gynecological oncologists should pay attention to the protection of ovarian function in patients with gestational trophoblastic neoplasia during perioperative chemotherapy.
Cardiovascular implications in adolescent and young adult hypertension
Authors: Raina Rupesh , Khooblall Amrit , Shah Raghav , Vijayvargiya Nina , Khooblall Prajit , Sharma Bhavya , Datla Nikhil , Narang Aarushi , Yerigeri Keval , Melachuri Manasa , Kusumi Kirsten
Published: May 2022

Background: Hypertension is one of the most prevalent diseases in the United States, affecting an estimated 3.5% of children and adolescents. It can be adversely affect most organ systems but is particularly detrimental to the heart and vascular systems. The repercussions can be gauged through well-established measures of cardiovascular function including left ventricular mass index (LVMI), left ventricular hypertrophy (LVH), carotid intima media thickness (cIMT), and aortic stiffness. Cardiovascular function is also affected by underlying etiologies of hypertension including chronic kidney disease, polycystic kidney disease, coarctation of the aorta, adrenal disorders, renal artery stenosis, obstructive sleep apnea, as well as various drugs and medications (decongestants, stimulants, Non-steroidal Anti-inflammatory Drugs (NSAIDs), and steroids). Methods: An exhaustive literature search was conducted for clinical data regarding pediatric hypertension. Sixty-seven articles were incorporated with data on 189,477 subjects total. The data was then extracted and categorized as relating to hypertension incidence, LVMI, LVH, cIMT, and/or aortic stiffness. Results: The prevalence of pediatric (<18 years) hypertension extracted from 47 studies from 1994 to 2018 averaged 4%. The LVMI assessed over 7 studies (n = 661) averaged 39.3 g/m2.7 in the hypertensive cohort and 30.1 g/m2.7 in the control cohort. The cIMT assessed over 7 studies (n = 580) averaged 0.55 mm in the hypertensive cohort and 0.49 mm in the control cohort. Ambulatory arterial stiffness parameters assessed over 5 studies (n = 573) in the normotensive cohort averaged 99.73 mmHg, 69.81 mmHg, 76.85 mmHg, and 46.90 mmHg, for SBP, DBP, MAP, and PP respectively. Ambulatory arterial stiffness parameters assessed over 5 studies (n = 573) in the hypertensive cohort averaged 129.56 mmHg, 73.69 mmHg, 95.08 mmHg, and 56.80 mmHg, for SBP, DBP, MAP, and PP respectively. Conclusions: The significance of pediatric hypertension is emphasized by evidence of early cardiovascular disease as demonstrated by non-invasive measures including cIMT and arterial stiffness parameters, and target organ damage and including LVH and LVMI factors. Thus, early diagnosis and treatment of high blood pressure is paramount for improving long term cardiovascular health and preventing long term morbidity and mortality.
Approach to Acute Phase Reactions in the Aspects of Pathology and General Situation in Turkey
Authors: Dayı Belma , Sevimli Alper
Published: May 2022

This review evaluates the importance of acute phase proteins (APP) and acute phase reaction (APR), which are accepted as sensitive biomarkers in diagnosing of animal diseases, both in general and pathological terms, with a particular emphasis on the situation in Turkey. Pathological examinations have been extensively used in studies investigating the APP and APR in veterinary medicine globally. In contrast, the number of studies and pathology involvement is limited in Turkey. For this reason, we conducted a qualitative and quantitative analysis of the studies in the world and in Turkey to emphasize the importance of the subject and increase awareness among the clinicians. The review is the first comprehensive report on the subject in Turkey and is supported by a regional map of the distribution of performed studies.
Portuguese version of the Firefighter Coping Self-Efficacy Scale: Factor structure and psychometric characteristics
Authors: Moniz Soraia , Galhardo Ana
Published: May 2022

Background and Aim: The current study aimed to translate the Firefighter Coping Self-Efficacy Scale (FFCSE) and explore its dimensionality and psychometric characteristics. Method: This cross-sectional study was authorised by the National Emergency and Civil Protection Authority and disseminated by firefighters' stations from different districts. A sample of 155 firefighters completed online the following self-report instruments: Firefighter Coping Self-Efficacy Scale, Comprehensive Assessment of Acceptance and Commitment Therapy Processes, World Health Organization Index-5, Perceived Stress Scale and Patients Health Questionnaire-4. An exploratory factor analysis was computed, and reliability and validity studies were conducted. Results: The Portuguese version of the FFCSE items revealed, in general, good psychometric characteristics, except for item 10 ("Having dreams about difficult calls"). The factor structure was one-dimensional. The FFCSE showed good internal consistency, and the associations with the other variables were in the expected direction. No differences were found between men and women in the FFCSE mean scores. There was no statistically significant association between the FFCSE and age, years of education or length of service as firefighters. Conclusions: The FFCSE proved to be a one-dimensional measure of perceived self-efficacy to deal with the demands inherent to the firefighter activity. The results suggest that it is a valid and reliable measure, useful in research, clinical and training contexts for these professionals.
APA Belief Change
Authors: Trevors Greg
Published: May 2022

A goal of educational efforts, whether in formal or informal learning environments, is to expand individuals’ knowledge of some phenomenon. Increasing knowledge is commonly thought to be attained by presenting new information in a clear, accessible manner, and scaffolding learners as active agents in integrating their prior knowledge and experiences to new information and constructing meaning from the new connections that emerge. Achieving this goal is challenging even under ideal conditions but it is especially complicated when a learner’s prior beliefs conflict with the to-be-learned content. Developing theory and practical solutions for this complicated scenario has been the decades-long undertaking of belief change research and is the focus of the current chapter.
Peran Lingkungan Terhadap Pembelajaran Bahasa Indonesia
Authors: Ramadhona Syahri
Published: May 2022

Lingkungan sangat berpengaruh disegala segi kehidupan, tak terkecuali dalam dunia pendidikan. Pada proses pembelajaran khususnya pembelajaran bahasa Indonesia, lingkungan juga memiliki andil dalam mempengaruhi kualitas belajar siswa. Pengaplikasian pembelajaran berbasis lingkungan dirasa dapat meningkatkan minat belajar siswa. Selain itu, hal tersebut juga mampu mengurangi rasa jenuh siswa dalam proses belajar mengajar. Tidak hanya sebagai penunjang proses pembelajaran di dalam kelas, lingkungan juga memiliki pengaruh yang sangat besar terhadap kemampuan berbahasa Indonesia peserta didik. Pengaruh lingkungan terhadap kemampuan berbahasa Indonesia peserta didik ini juga berperan penting dalam pembelajaran bahasa Indonesia. Jadi hal tersebut membantu peserta didik untuk memiliki kemampuan berbahasa Indonesia yang baik sehingga peserta didiktersebut mampu mengaplikasikannya dalam proses pembelajaran bahasa Indonesia.
Makalah Perbedaan Koperasi Dengan Organisasi Lainnya
Authors: Jannah Miftahul , K Khelvin. , yuniarti ervie , ramdhani ulfa , Sugiatni Evi
Published: May 2022

Saat ini di Indonesia mengenal ada 3 bentuk usaha bisnis, yang meliputi BUMN, BUMS, maupun Koperasi. Pembagian bentuk badan usaha ini bersumber pada UUD 45 Pasal 33. Pada pasal itu, terdapat konsep Demokrasi Ekonomi bagi perekonomian Negara. Dalam konsep itu ada kebebasan bagi tiap warga negara untuk melakukan usaha, namun ada batasan-batasan yang harus di patuhi. Batasan itu meliputi 2 hal yaitu: jenis usaha vital, dan usaha yang menguasai hajat hidup orang banyak dikuasai oleh negara. Dalam makalah ini, kami akan membahas mengenai Perbedaan koperasi dengan organisasi lainnya.
A Study on the Changes of Vietnam since 1970’s - Focusing on the Good Governance Policies Implemented by International Organizations
Authors: Mai Nhat Chi
Published: May 2022

This paper is a study on the factors affecting the changesof the political system of Vietnam that has attempted a reform within the system through its reform and open-door policy. The study originates in the interest in whether Vietnam could continue its changes of system via economic reform, and whether the economic reform could affect the reform of the political system. One assumption of the study is that the answer to which path Vietnamese socialism would take should be first found in understanding the factors influencing the changes of the system of Vietnam.
Materi Teori Nilai Guna (utility)
Authors: Nurfadilah
Published: May 2022

utility atau nilai guna seing digunakan sebagai istilah untuk menjelaskan mengenai suatu manfaat barang atau komoditas tertentu. Pada teori keseimbangan, diketahui bahwa teori keseimbangan menggambarkan antara kesesuaian antara permintaan dan penawaran.
Kant‘s Groundwork of the Metaphysics of Morals
Authors: Ajvazi Irfan
Published: May 2022

Kant's analysis of ordinary moral consciousness reveals that people believe they are bound by duty. Duty, in turn, Kant explains, "is the necessity of an action from respect for law." All inclination to the contrary, and even inclination toward duty is set aside, so that the only motivation is respect for law. The binding power of the law reflects not only a universal command but also a universal command of reason. After all, given that the realm of experience is, by nature, contingent, no empirical fact can command as completely. Reason's command is an imperative: it is what must be done. When one does one's duty for its own sake, then one acts from respect for the moral law.
Pelaksanaan Katekisasi di Jemaat Pniel Sikumana
Authors: Kaseh Evita Bonita Omi
Published: May 2022

Penelitian ini dilaksanakan untuk melihat masalah pokok tentang bagaimana pelaksanaan katekisasi yang ingin dicapai oleh gereja beserta dengan tujuan, metode dan bahan kajian dalam rancangan pembelajaran katekisasi.Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mencari tau rancangan pembelajaran katekisasi yang ingin dicapai oleh gereja beserta dengan tujuan, met0ode dan bahan kajian yang dipakai untuk mencapai pembelajaran katekisasi. Untuk mendapatkan hasil penelitian maka metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan teknik atau pendekatan evaluasi Robert E. Stake. Tujuan dari penggunaan metode ini adalah untuk mendeskripsikan apa yang disampaikan narsumber terhadap pembelajaran katekisasi yang dilakukan. Yang perlu dilakukan dengan tahapan: Persiapan atau pendahuluan (antecedents), pelaksanaan pengembangan kurikulum dan penyediaan sumber daya pendidikan, Proses/transaksi (transaction-processes), pelaksanaan kegiatan pembelajaran,Keluaran atau hasil (outcomes, output), kemudian peneliti melakukan proses evaluasi untuk menentukan hasil. Dari hasil penelitian yang dilakukan di peroleh beberapa kesimpulan sebagai berikut; Rancangan pembelajaran katekisasi yang ingin dicapai gereja adalah menjadikan anak-anak semakin berguna bagi diri sendiri, sesama, bangsa dan Negara dan terlebih untuk Tuhan. Metode yang seringkali digunakan dalam proses pembelajaran katekisasi adalah metode ceramah, diskusi, tanya-jawab, penugasan, demonstrasi, latihan dan evaluasi. Metode evaluasi pada pembelajaran katekisasi sering digunakan karna pada metode ini anak-anak diharuskan untuk membuat renungan kemudian berkotbah. Bahan yang perlu dikaji sekarang adalah kerja sama antara pengajar dan gereja yang baik di dalam administrasi maupun dalam pembinaan peserta katekisasi yang kedepannya benar-benar mempersiapkan manusia yang berkomitmen pada panggilan Tuhan untuk kedepan mereka tetap berjalan pada kehendak Tuhan. Oleh karena itu pihak gereja beserta dengan pengajar perlu berusaha dan berupaya dengan mencari jalan keluar dalam memberikan perhatian khusus kepada pelaksanaan kegiatan katekisasi yang lebih baik lagi dari semua segi.
Wealth Effects of Mergers and Acquisitions on Vietnamese Listed Firms
Authors: Mai Nhat Chi
Published: May 2022

The Vietnamese economy experienced its first major mergers and acquisitions (M&As) wave in the period from 2007 to 2013. This study analyses the wealth effects of M&As on Vietnamese listed firms. I use the event study method and apply the market model to evaluate the performance of target and acquirer firms. By examining the effect of Vietnam’s specific institutional aspects on cumulative abnormal return (CAR), I find that state-ownedenterprise (SOE) targets have higher CARs over non-SOE targets but not statistically significant; M&A deals in financials and materials industries show significant positive returns than the others do; domestic M&A brings higher returns to targets than inbound M&A activities and there is no statistical difference of M&A performance regarding the listing location. The results also indicate a significantly positive abnormal return from M&A activities for target firms, evidencing that M&A activities create value to shareholders of the targets.
PERENCANAAN LANSKAP KAWASAN WISATA ALAM PEMANDIAN AIR PANAS TIRTA SAYAGA, KABUPATEN BOGOR
Authors: Ningtias Nadia Parras , Purwono Rudi
Published: May 2022

Bogor regency has many tourism potentials, one of which is water tourism thermal baths Tirta Sayaga Water tourism thermal baths Tirta Sayaga has a tourist attraction in the form of hot spring and the existence of a Bocca Travertine or known as mount kapur. Water tourism thermal baths Tirta Sayaga area requires landscape planning and design to increase tourism attractions. This research was conducted using the perception and preferences analysis method and then processed by chi-square method, carrying capacity analysis and vegetation analysis as directions in determine of planning. The result of the analysis show an overview of the planning of the water tourism thermal baths Tirta Sayaga area is a health and recreation tourism area for visitors that is equipped with tourist service facilities, so that visitors feel comfortable and satisfied, connected to a circulation system that covers the entire site, and decorated with a green layout.