bluuebunny/crossref_metadata_2025 huggingface dataset:
Dismetría y características posturales en personas con amputación de extremidad inferior y análisis de su alineación protésica
Authors:   , López Bravo J. L.
Published: December 2021

Lower limb amputees (LLAm) with prosthetic limbs get through alignment and leveling processes to assure the correct function of their device. However, errors in this process may led to lower limb asymmetry (LLA). Depending on the magnitude of the LLA there is a greater risk of presenting postural asymmetry, gait disturbances, low back pain, and structural deformities. Therefore, the main objective of this article is to determine LLA and alignment and postural features of people with lower limb (LL) amputation using the software Kinovea. Nowadays there is not much literature about the postural and asymmetry analysis of LLAm. The method followed to calculate the asymmetry was to first do the software calibration with a chosen reference segment, then each leg segment was measured using Kinovea to obtain the absolute difference between them. The angles of knee flexion and alignment were also analyzed with the help of marks previously placed in the subjects’ points of interest. Among the 16 subjects, 8 presented an asymmetry level I, 3 a level II and 5 a level III, in the lateral position. The longest LL of 11 of the 13 unilateral amputees presented the smallest knee flexion angle. The subjects’ knee stability was classified as stable for 7 of them, as unstable for 9 and only 1 subject as extremely stable. The main application of the results obtained would be to use the information to create a database that can be used for future research and as feedback for prosthetists and orthotists.
Férula con terapia de luz roja e infrarroja para el síndrome del túnel carpiano
Authors:   , Cameras Cruz E. D.
Published: December 2021

El síndrome del túnel carpiano afecta a gran variedad de personas, en ellas se destacan mujeres entre los 40 y 60 años, impidiendo continuar con sus actividades de manera eficaz. El siguiente trabajo ha sido realizado para ayudar a las personas con dicho síndrome, haciendo uso de férulas impresas mediante impresión 3D y terapias de luz (LLLT) el uso del láser terapéutico de baja intensidad (Low-level-Laser Therapy) ha traído consigo la evolución de los tratamientos antiinflamatorios, analgésicos y procicatrizantes, debido a la foto estimulación celular sobre la mitocondria; esto incrementa la generación de energía (ATP), que acelera la microcirculación sanguínea y produce cambios en la presión hidrostática del capilar, en este trabajo se describe como fue el proceso para la creación de la férula y los pasos a seguir para llegar a dar la terapia de luz roja e infrarroja.
Dispositivo para la estratificación de las propiedades visco-electro-elásticas de la piel
Authors:   , Lopez Jimenez D. A.
Published: December 2021

Objective: Measure the mechanical properties, galvanic response, and elasticity of the skin through the use of different techniques grouped in a multifunctional and wireless device. Results: The device built was able to collect, compute and send the data from the different sensors that make it up, to a database in Firebase for post-processing. Regarding the readings obtained, it can be observed that the height reached by the skin of the subjects has a considerably prolonged retraction time compared to the gradual decrease of the negative pressure in the indenter light, in addition, the electrical resistance does not seem to have a relationship with this phenomenon during this study, since this measurement is not very variable in each subject, but diverse among them. Conclusions: The data obtained show that the device is capable of measuring different height rates between subjects under the same environment, although all in different health conditions, so through this it is presumed that the properties of elasticity, electroconductivity and viscosity, among subjects with conditions of the integumentary tissue and thus create a pattern of their behavior, under the tests that appear in this work.
Índice de desempeño para tareas de atención sostenida
Authors:   , Francisco-Vicencio M.
Published: December 2021

Through this work, we explore the idea of a translational attentional index that can be utilized in cognitive evaluation practice as well as in other areas in the biomedical space. With the increase of virtual assistants developed for in-house rehabilitation session monitoring – such as wearables and computer vision (CV) based AI assistants –, the standardization of an index based on behavioral indicators is imperative to give them the ability to monitor the users’ engagement level in the given task to procure a safety and effective execution. We begin by exploring the indicators of attention obtained from a Continuous Performance Test (CPT) – a standardized tool utilized in cognitive evaluation – where we detect shortcomings that cannot be translated to daily life scenarios where this index is intended to be used. We propose then an index that is computed based on common indicators that can be found in daily tasks (Correct Responses and Reaction Times) by weighting their contributions equally and bidirectionally penalizing variability on responses recorded. We close with presenting the information the new index can group from common indicators and that can be easily interpreted in a quick sight by different professionals in the biomedical space compared with the typical analysis of attentional levels obtained from a CPT.
Traductor al Alfabeto Dactilológico basado en la Lengua de Señas Mexicana (LSM)
Authors:   , Hernández González P.
Published: December 2021

En este trabajo, se presenta el desarrollo de un dispositivo con la capacidad de enseñar el alfabeto dactilológico basado en la LSM. Los alcances de este dispositivo es representar dieciséis letras del alfabeto dactilológico. Este proyecto surge de proveer una herramienta que facilite la enseñanza del alfabeto dactilológico. La dificultad de las personas sordas para comunicarse disminuye su capacidad de interacción social; en consecuencia, su desarrollo educativo, profesional y humano quedan restringidos seriamente, lo que limita las oportunidades de inclusión que todo ser humano merece. Este dispositivo no está limitado para que sólo las personas sordomudas puedan aprender el alfabeto dactilológico, sino que está diseñado para que todos puedan aprender de manera visual y auditiva, esto respetando el propósito de poder ayudar a las personas que sufren esta discapacidad, ofreciendo a la sociedad el papel de poder aprender y que de esta manera se tome en cuenta al porcentaje de la población con esta dificultad.
Estudio de caso: Análisis fractal de Higuchi y Katz para señales de actígrafo de bajo costo
Authors:   , Martínez-Peón D.
Published: December 2021

The present work demonstrates alow costactigraph to monitor motor activity while a person performs the task of going to bed. To corroborate its performance, two types of experiments were performed, in the first one the device was placed on a subjectto study the first 8hours of sleep, in the second one it was placed on a table during the same hours. Two fractal-based algorithms, Higuchi and Katz,were implemented to process the signals obtained. The signals were divided into two blocks when the device was placed on the subject, block 1 when there was a lot of motor activity once the subject was lying down, and block 2 when no motor activity was detected. ANOVA tests were run, and no significant differences were found between blocks 1 and 2, however, significant differences were found, for both algorithms, when the subject was using the device and when the device was left on the table. The implication of this result is that a device is available at low cost that can be used to verify whether the subject puts on the deviceto analyze motor activityor decides to take it off, for example, when they are asked to participate in an experiment that requires sleep for several hours.
Características clínico-epidemiológicas y factores de riesgo de mortalidad en pacientes adultos con COVID-19 atendidos en la UMF-28 del IMSS, Ciudad de México
Authors:   , Martínez-Arellano Kevin
Published: December 2021

To evaluate the clinical characteristics and risk factors associated with mortality in patients with coronavirus 2019 (COVID-19) treated at the Family Medicine Unit #28 of the Mexican Institute of Social Security (IMSS) during a specified period. A retrospective, cross-sectional and descriptive based on the clinical history of patients with COVID-19 aged 18 to 90 years seen at the Family Medicine Unit #28 of the IMSS, Mexico City, during the period from March 2020 to March 2021 Inferential analysis to investigate the association between categorical data and COVID-19 severity was performed using the Chi-square test. Conditional logistic regression was used to estimate the odds ratios (OR) of the factors associated with COVID-19 mortality such as age, sex, and smoking, with 95% confidence intervals (CI). the Kaplan-Meier method with a log-rank test to draw survival curves in patients with and without comorbidities and the case fatality rate was estimated by variable cases. Our study indicates that male patients older than 60 years with comorbidities obtain an increased mortality risk from COVID-19. Diabetes, hypertension, obesity, COPD, renal and cardiovascular diseases are the most frequent comorbidities traits associated with a severe COVID disease and a higher mortality risk in the Mexican population (p<0.001). Covid-19 patients with kidney disease have a lower survival probability. This study revealed the epidemiological and clinical characteristics of the confirmed positive cases of COVID-19 in Mexico. Which should be considered to improve management actions in vulnerable populations and identify patients who need early medical attention to prevent complications from COVID-19.
Segmentación de imágenes de resonancia magnética utilizando filtrado espacial y aprendizaje profundo
Authors:   , Rosas-Castillo L. A.
Published: December 2021

El procesamiento de imágenes de resonancia magnética provee información valiosa acerca del estado del órgano estudiado, esto ayuda a la detección y tratamiento de patologías. Uno de los métodos de procesamiento más utilizados es la segmentación, que se refiere a la diferenciación de tejidos o zonas relevantes dentro de una imagen.La mayoría de las plataformas y aplicaciones que incluyen herramientas de segmentación, requieren que el usuario realice la segmentación de forma manual o en su defecto, que ingrese o modifique parámetros que influyen en procedimientos de la segmentación, haciéndola semi-automática. En este trabajo se plantea un sistema de segmentación automatizada en imágenes de resonancia magnética cerebral, conformado por una etapa de filtrado espacial seguida de una etapa de predicción hecha por una red neuronal convolucional. El sistema segmenta una imagen cerebral en cuatro componentes: fondo, materia blanca, materia gris y líquido cefalorraquídeo. Bajo el método de validación cruzada, arroja un promedio de los valores de precisión del 98.259(1.038)%.
Tranilast treats cold-related hypertension by reducing the expression of NLRP3 inflammasome
Authors: Yu Hui , Zhou Yun , Duan Yu , Gao Yunlong , Fang Ning , Zhang Jiawei , Li Yue
Published: December 2021

Objective

Cold exposure is associated with increased prevalence of hypertension and the related severe cardiovascular events. Aberrant activation of the nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome plays an important role in the development of hypertension. Tranilast (TR), an inhibitor of NLRP3, provides a useful pharmacological probe for exploring the role of NLRP3 in pathogenesis associated with inflammation and its potential application as a therapeutic agent. This study was designed to examine the effects of TR on NLRP3 and hypertension in rats exposed to cold environment to simulate the frigid-zone conditions.

Methods and results

Sprague Dawley (SD) rats were exposed to moderate cold temperature (4±1°C), and then were randomized to receive TR or vehicle for 3 weeks, while the control group was raised under rat room temperature (RT, 23±1°C). We found that cold exposure substantially increased blood pressure, NLRP3 inflammasome level, and fibrosis in aorta, which were reversed by TR.

Conclusion

TR has an anti-hypertensive property in cold environment, and this beneficial action is likely conferred by its inhibitory effects on inflammation and fibrosis. These findings suggest TR as a potential drug for the treatment of cold-induced hypertension.
Parameterless Pruning Algorithms for Similarity-Weight Network and Its Application in Extracting the Backbone of Global Value Chain
Authors: Xing Lizhi , Han Yu
Published: December 2021

Purpose

With the availability and utilization of Inter-Country Input-Output (ICIO) tables, it is possible to construct quantitative indices to assess its impact on the Global Value Chain (GVC). For the sake of visualization, ICIO networks with tremendous low- weight edges are too dense to show the substantial structure. These redundant edges, inevitably make the network data full of noise and eventually exert negative effects on Social Network Analysis (SNA). In this case, we need a method to filter such edges and obtain a sparser network with only the meaningful connections.

Design/methodology/approach

In this paper, we propose two parameterless pruning algorithms from the global and local perspectives respectively, then the performance of them is examined using the ICIO table from different databases.

Findings

The Searching Paths (SP) method extracts the strongest association paths from the global perspective, while Filtering Edges (FE) method captures the key links according to the local weight ratio. The results show that the FE method can basically include the SP method and become the best solution for the ICIO networks.

Research limitations

There are still two limitations in this research. One is that the computational complexity may increase rapidly while processing the large-scale networks, so the proposed method should be further improved. The other is that much more empirical networks should be introduced to testify the scientificity and practicability of our methodology.

Practical implications

The network pruning methods we proposed will promote the analysis of the ICIO network, in terms of community detection, link prediction, and spatial econometrics, etc. Also, they can be applied to many other complex networks with similar characteristics.

Originality/value

This paper improves the existing research from two aspects, namely, considering the heterogeneity of weights and avoiding the interference of parameters. Therefore, it provides a new idea for the research of network backbone extraction.
Determining the area corrections affecting the map areas in GIS applications
Authors: Yildirim Faruk , Kadi Fatih
Published: December 2021

Nowadays, there are many area-based Geographic Information Systems (GIS) applications such as real estate valuation, land tax, farming support and cost–benefit analysis. Areas used in such applications are calculated by means of two-dimensional plane geometry. However, the computed area value is not the exact area value in the terrain. In order to calculate the exact area value of a parcel, area corrections due to various factors must be taken into account. These factors are selection of projection, slope of the terrain, elevation of the terrain and scale of the map. Selection of projection and slope of terrain are available; elevation of the terrain and scale of map are not available in all GIS software. In this study, the effect of area corrections on the area value calculated from the map is examined with sample applications and the results are presented to the GIS users. According to the results, GIS users should select the equal area projection. In addition, scale of map, elevation and slope of terrain should be taken into account in the area calculation where land measurements are not possible.
Forecasting the impact of buildings with multi-storey underground parts on the displacement of subsoil using modern numerical tools
Authors: Michalak Hanna , Przybysz Paweł
Published: December 2021

The paper will analyse and review the experience to date in determining the impact range of implementation of deeply founded structures on the displacement of the subsoil in the vicinity.

With the background of these experiences, primarily empirical, the present possibilities of using numerical modelling to forecast the displacements of the terrain surface in various stages of works, that is, execution of deep excavation support systems, excavation-deepening phases with successive adding of struts, construction of underground levels and erection of the above-ground part of the building, will be presented.

Based on the results of own research, conclusions on the use of 3D numerical models in spatial shaping and designing the structure of underground parts of new buildings erected in dense urban development will be presented. The characterised 3D numerical models were verified, taking into account the actual results of geodetic measurements of the completed buildings.

Determining the range and forecasting the displacements of the subsoil are necessary for the design and implementation of investments due to the need to ensure the safety of erection and use of a new building and the buildings located within the area of influence.
Under-Utilization of Maternal-Child Healthcare Services and Adverse Outcomes of Unwanted Pregnancies in Urban and Rural Areas of Indonesia
Authors:   Department of Public Health and Nutrition, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia, Astiarani Yunisa , . Maybelline ,   School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia, Putri Giovani I.G. ,   School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia, Fitriah Nur ,   Department of Public Health and Nutrition, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia, Kurniawan Felicia ,   School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
Published: December 2021

The study examines the association of unwanted pregnancy and the utilization of maternal-child health services, and the adverse health outcomes in urban and rural settings. The study employed data from the 2017 Indonesia Demographic Health Survey that included 13,806 live births; the mothers were not pregnant at the interview and were married participants. The multiple logistic regression analysis concerning residential areas was conducted separately to compare outcomes related to unwanted pregnancy. Non-standard antenatal care visits (adjusted odds ratio [AOR]=1.7; 95% confidence interval [CI]=1.2–2.4), prolonged labor (AOR=1.6; 95% CI=1.2–2.1), the absence of child’s birth documentation (AOR=1.3; 95% CI=1.0–1.6), and smaller baby size (AOR=1.2; 95% CI=1.0–1.4) are associated with unwanted pregnancy in urban areas. In rural settings, on the other hand, unwanted pregnancy is associated with non-standard antenatal care (AOR=1.6; 95% CI=1.2–2.2). Therefore, in Indonesia, urban areas lack maternal-child healthcare services utilization and higher adverse events due to unwanted pregnancy than rural areas. An adjustment approach is required in maternal-child health-related programs in both areas, particularly for women living in urban.
Processing Effect on Antioxidant Composition of Processed Products of Wild Edible Fruits of Sikkim Himalayas
Authors: Sherpa Ningma Doma , Bhutia Karma Diki
Published: December 2021

The processing effect on the processed products of wild edible fruits found in Sikkim Himalayas namely Chuirri (Diploknema butyracea), Achuk (Hippophae salicifolia), Mehel (Docynia indica), Muslendi (Elaeagnus latifolia) and Famphal (Machilus edulis) was quantified in this study. The value of the fruits is high enough to contribute and enhance the nutrient daily requirements of humans. Therefore, a study to assess the loss or change in their antioxidant composition before and after processing was carried out. The phytochemical characteristics of the fruits were analyzed according to standard methods on both the fresh and its various processed products. Comparing all the five wild fruits and their processed products, it was observed that there was a significant loss of nutrients during processing which occurred in its bioactive compound and composition of their processed foods. Although it has a potential to be a source of antioxidants, other nutrients also implement for utilization as food preserves and consumed in the form of food supplements. It will be promote the nutritional potential of the wild fruits as well as add value to the processed products among local people for consumer acceptability which can be further fortified as export items and to uplift the socio-economic status of the local community.
Endophytic Fungi as a reservoir of Lignocellulolytic Enzymes- A Review
Authors: Pundir Ram Kumar , Jain Pranay
Published: December 2021

The potential use of microorganisms as biotechnological sources of industrially important enzymes has stimulated interest in exploration of extracellular enzymatic activity in several microorganisms. Endophytic fungi are those fungi which colonize plants internally without apparent adverse effect. Endophytic fungi are relatively unexplored producers of metabolites useful to pharmaceutical and agricultural industries. As a result, the role of endophytes in production of various natural products with greater bioactivity has received increased attention. Endophytic fungi have been found to degrade lignocellulose consisting of lignin, cellulose and hemicellulose with the aid of lignocellulases enzynes. This review highlights the potential of endophytic fungi for production of lignocellulases and also discusses the present status and future prospectives in this field.
Comparison of mixed and plug flow reactor for enhancing the cell concentration of Haematococcus pluvialis growth
Authors: Vasumathi K. , Nadana Raja Vadivu G. , Nithiya E.M. , Sundar K. , Premalatha M.
Published: December 2021

Photo bioreactions are employed for abating carbon dioxide emissions. The economics depends upon the choice of the type of the reactor. Photo bioreactions can be explained similarly to an autocatalytic reaction. A combined reactor mixed flow reactor followed by plug flow reactor could be the best choice. Using the data on cell concentration of Haematococcus pluvialis with respect to time in 2x concentration of Kobayashi’s basal medium available in the literature, it has been proved that the combined reactor could be the best choice. The optimum combination was also determined.
Modern biotechnology tools and biosecurity in the Middle East
Authors: Roua Alsubki
Published: December 2021

The global health system is under a constant threat from microbial outbreaks. The innovation in genetic engineering has created an existential threat to national, regional and international security. This threat, that can edit microbial or human genomes, requires global attention. In the current review, a comprehensive literature search was conducted using PubMed, SCOPUS and Google Scholar to identify literature discussing modern biotechnology tools as well as relevance to biosafety in the Middle east region. This review was undertaken to provide an overview of biological threats due to advancements in genetic engineering, making it possible to insert or delete specific genes to increase the virulence of particular microbes. These pathogens or other toxic factors can be multiplied by technology, creating new biological weapons. Genome editing technologies including meganucleases (MNs), zinc finger nucleases (ZFNs), transcription activator-like effector (TALE)-nucleases (TALENs) and recently discovered clustered regularly interspaced short palindromic repeats (CRISPR/Cas) induce a double strand break at specific DNA target site. Genome editing technologies lead to an irreversible and permanent alteration of the genetic code and therefore, can inevitably result in security risks. Vulnerabilities in Middle Eastern laboratories raise the prospect of high levels of pathogenic microbes potentially creating a weakness in the diagnosis and monitoring of epidemics. Furthermore, the lack of regional legislation to regulate biosafety and biosecurity may lead to biological threat at the regional level.
miRNA biogenesis, function and their therapeutic implications
Authors: Pathak Surajit , Prasad Veronica Suhanya , Banerjee Antara
Published: December 2021

Research in microRNA has witnessed a significant breakthrough as it is significantly involved in numerous biological processes. MicroRNAs are short (~22 nucleotides) non-coding RNAs, are cell/ tissuespecifically expressed and are temporarily regulated. They regulate post-transcription output of proteins by targeting mRNAs for translational repression or degradation. This review is written with searches related to current trends and application of miRNAs from databases of Pubmed and Google. microRNAs are known to participate in developmental and physiological processes and their dysregulation contributes to various disease progression. The benefit of using microRNA approaches depends on its ability to simultaneously target multiple effectors of cell differentiation, proliferation and survival pathways. Dysfunctional miRNAs have been implicated in the development of various disorders. These small RNA molecules serve as post-transcriptional regulators of gene expression and are considered as reliable clinical biomarkers. Considering its tissue and disease-specific expression involving pathophysiological processes, microRNAs are proposed as useful biomarker for prognosis, assessing disease risk. microRNAs can serve as potent biomarker for cancer and other diseases such as neurodegenerative diseases, cardiovascular diseases and diabetes. This review mainly focuses on emphasizing the biology, dysregulation associated with various disease models and use of microRNAs as potential biomarkers for disease diagnosis.
Electroporation-enhanced entrapment of diclofenac sodium and ascorbic acid into DPPC liposomes
Authors: Fahmy Heba M. , Idris Amani M.R. , Elsayed Anwar A. , Mohamad Ebtesam A.
Published: December 2021

The effect of electroporation on the physical characteristics of 1,2-dipalmitoyl-Sn-glycerol-3- phosphocholine (DPPC) liposome loading diclofenac sodium, ascorbic acid and Rhodamine B was studied. Group one liposomes were incubated with diclofenac sodium, group two liposomes were incubated with ascorbic acid and group three: liposomes were incubated with Rhodamine B. The three groups were subjected to electroporation protocol. Samples were exposed to different field strengths at pulses 30, 60 and 90 pulses respectively with pulse duration 4 milliseconds. After electroporation, liposomes were separated from unentrapped drugs and form the dye through centrifugation. Physical characteristics of liposomes were examined using Transmission electron microscope (TEM), Confocal laser scanning microscopy (CLSM) and particle size analysis. Liposomes are entrapping ascorbic acid with high efficiency at the values of 900 V/0.2 cm with 60 pulses, 800 and 1000 V/ 0.2 cm at 90 pulses. Diclofenac sodium was entrapped at 800 V/0.2 cm and 90 pulses. Rhodamine B was entrapped at 500 and 1000 V/0.2 cm at 30 pulses. Based on the present results, entrapping of diclofenac sodium and ascorbic acid into liposomes can be controlled efficiently by electroporation technique. Optimum entrapping occurred at 800 V/0.2 cm and 90 pulses for ascorbic acid and DS at 900 V/0.2 cm and 30 pulses for Rh-B.
Molecular simulation approach integrated with deep learning model for the discovery of Tankyrase inhibitors
Authors: Subburaj Saranyadevi , Veerappapillai Shanthi
Published: December 2021

Tankyrases belong to the poly (ADP-ribose) polymerase family epitomized as a novel group of medicinal targets with various prospective diseased conditions and it is appraised to be a challenging drug target for the intervention of multiple cancers. Thus, the principal objective of our study is to explore the dual-site selective tankyrase 1 inhibitor by employing the pharmacophore strategy. Initially, the ligand-based pharmacophore study generated five featured pharmacophore hypothesis, which was then employed for the database screening. The screened molecules were scrutinized through docking, MM/GBSA calculations and molecular simulation alongside pharmacokinetics properties. The analysis yielded potent dual-site tankyrase 1 inhibitors such as nebivolol and ondansetron from the DrugBank repository. Notably, the recognized lead molecules were perceived to have higher XP GScore and binding energy scores. Subsequently, simulation studies were executed to validate the structural stability of the lead molecules. It is worth mentioning that the existence of benzopyran and carbazole scaffolds in the lead molecules displayed anti-neoplastic activity and also facilitate the effective binding with tankyrase 1 protein. Ultimately, the IC50 values of the lead molecules were examined against the NCI-H596 cell line using a deep learning model. Indeed, these results are of immense importance and provide a clue to the experimental biologist in developing a potent tankyrase 1 dual-site inhibitor.
Childhood Obesity Management at the 9-11 Year Well Child Check-An Opportunity for Expert Committee Recommended Comorbidity Screening
Authors:   Department of Pediatrics, Akron Children’s Hospital, Akron, Ohio, M Komer , S Ben-Zion ,   Department of Pediatrics, Akron Children’s Hospital, Akron, Ohio, R Raina ,   Department of Pediatrics, Akron Children’s Hospital, Akron, Ohio
Published: December 2021

Our study assessed how primary care providers in a large outpatient network follow ECR guidelines with regards to laboratory screening for comorbidities of obese patients in the 9 to 11 year age group. This retrospective cohort study included 706 patients seen in an outpatient network with a 10 year well child check from 7/1/17 to 7/1/18 and a BMI greater than or equal to the 95th percentile. Our study found 42% of patients, who met ECR guidelines, had no lipid screening or obesity co-morbidity screening obtained. The most frequently abnormal test was the lipid panel, at 23%, and notably 16 % of Hemoglobin A1C screening resulted pre-diabetic range. Our study serves as an updated review of ECR compliance in a large primary care network and suggests an opportunity to enhance education on screening recommendations.
The High Importance Role of Epidemiology in Health Management
Authors:   Epidemiologist, Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, Iran, K Mobaraki , J Ahmadzadeh ,   Epidemiologist, Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, Iran
Published: December 2021

Epidemiology is a scientific discipline, sometimes called “the basic science of public health”. According to what it has done in the last 200 years, epidemiology is the science and practice. One of the areas that are less addressed in the literature is the important role of epidemiology in health management. The authors believed that one of the areas that epidemiologists can work is management debate.
Improving Management of Osteoarthritis: Patients’ Perceptions of a Surgical Readiness Interview Tool
Authors:   Schulich School of Dentistry and Medicine, Western University, London, ON, Canada, KI Barton , CE Hewison ,   Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, A Kania-Richmond ,   Bone and Joint Health Strategic Clinical Network, Alberta Health Services, Calgary, AB, Canada
Published: December 2021

Almost half of patients referred to orthopedic surgeons for Total Joint Arthroplasty (TJA) do not require TJA at that time or are not appropriate surgical candidates. The objective was to explore patients’ perspectives of a Surgical Readiness Interview Tool and its potential utility in the Osteoarthritis (OA) management process. Semi-structured qualitative interviews were conducted with a convenience sample of patients from arthroplasty clinics in Alberta. All interviews were digitally recorded and transcribed verbatim. Analysis was conducted iteratively, applying a constant comparison method. Nine patients were interviewed. Participants found the interview tool to be relevant and comprehensible. Suggestions were made on how to improve tool clarity and administration processes. Patient orientation versus that of the doctor, and expectation management emerged as salient factors in the meaningful application of the tool. As a result of the interviews, a revised tool was developed which incorporated the participant suggestions. Patients were positive about the interview tool and felt that it would lead to better care provision, particularly with incorporation of participants’ suggestions. The data suggest that the interview tool could improve the conversation on surgical readiness, conservative management, and addressing modifiable risk factors prior to TJA.
Delivering Bad News: Should Physicians Express their Emotions?
Authors:   Research Associate, Houston Northwest Medical Center, Houston, Texas 77090, USA, H Vignesh , M Jayram ,   Research volunteer, Houston Northwest Medical Center, Houston, Texas 77090, USA, R Belakere ,   Director of Hospital Medicine, Houston Methodist Willowbrook Hospital, 18220 TX-249, Houston, TX 77070, USA
Published: December 2021

The traditionally assumed medical dictum is that a physician who expresses his or her emotions in font of patients or their families is almost deemed unprofessional. This feeling may be common place, particularly among traditional physicians who still hold the belief that professionalism is endangered if physicians deliver bad news laced with their true emotions. Discussion of this important topic surfaces now and then and are then hidden away without definite answers possibly due to lack of attention by physician's fraternity to dispense with this out-of-date dictum. Though we understand the protection of professionalism is the basis for this practice, the topic is rarely revisited because the community of physicians remains distant from this sensitive issue, in spite of its importance in achieving high care satisfaction from patients and their families. In view of the increased emphasis on enhancing patients’ hospital experiences and satisfaction, the demonstration of sensitivity on the part of physicians in some form as a component of their compassionate care may require renewed attention.
Investigating the Benefits of Using 3D Camera Technology to Improve Wound Measurements in a Tissue Viability Service: Outcomes of a Pilot Implementation Study
Authors:   Tissue Viability Nurse Consultant, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, England, UK, BM King , K Doyle ,   Tissue Viability Nurse Consultant, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, England, UK, J Kelley ,   Research Fellow, Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, England, UK, C Taylor ,   Tissue Viability Nurse Consultant, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, England, UK, SF Davis ,   Research Fellow, Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, England, UK
Published: December 2021

Sub-optimal experience and outcomes for people with stalled wounds is common. Clinicians have limited methods for reliably and accurately measure wounds. Depth measurement is an important indicator of healing, and digital methods of imaging the wound may offer increased accuracy and enable clinical decision-making. This study aimed to implement a Panasonic FZ-M1 toughpad with WoundCareLite software version 1.5.0.0, to enable three-dimensional measurements in Tissue Viability (TV) service. Length, width, and depth measurement were compared with usual manual measurement using a paper ruler alongside a 2D photographic image. Statistical analysis included the comparison of wound dimension measures and a presentation of visual healing trajectories over 4 weeks using run-charts. 30 patients were recruited over five weeks (13 female and 17 male), representing 4% of the usual caseload. Manual measurement and 3D software automatic method demonstrated that the width and depth 3D auto measures were more accurate than manual measures but depth measures were often wrong thus making volumetric measures inaccurate. Consistent wound size measurement was feasible, and healing trajectories provide a useful means of continuous assessment. Technology guided measurement has potential benefits over manual measurement as a means of more accurately monitoring healing. In this case, depth measurement could not be accurately assessed in practice and further software innovation is indicated to enable outcome measurement in tissue viability services.
Kadınların obstetrik şiddet deneyimleri: Sistematik derleme
Authors: KAYA Zehra , HOTUN ŞAHİN Nevin
Published: December 2021

Amaç: Bu çalışmanın amacı kadınların maruz kaldıkları obstetrik şiddete ilişkin deneyimlerini inceleyen çalışma sonuçlarını değerlendirmektir. Yöntem: Literatür taraması “Pubmed, Scopus, Medline” veri tabanlarında 01-27 Ekim 2019 tarihleri arasında, “obstetric violence” anahtar kelimesi kullanılarak gerçekleştirildi Dahil etme kriterleri doğrultusunda araştırma kapsamına 15 çalışma alındı. Bulgular: Sistematik derleme sonucunda elde edilen bulgular; obstetrik şiddet prevalansı, obstetrik şiddete ilişkin farkındalık, rızasız bakım, onursuz bakım, fiziksel taciz, ihmal edilmiş bakım, mahremiyetsiz bakım, ayrımcılık içeren bakım olmak üzere sekiz başlık altında toplanmıştır. Obstetrik şiddet prevalansının %12-75 arasında değiştiği, kadınların obstetrik şiddete ilişkin bilgi sahibi ve farkındalığının olmadıkları belirlenmiştir. Kadınların %17.1-63.6’sının bakıma ilişkin rızalarının alınmadığını, %19.3-55.3’ünün sağlık personelinin küçümseyici, hakaret içerikli sözlerine maruz kaldığı, %13.4-46.9’unun sağlık personelinin tokat, vurma gibi kötü muamelelerine maruz kaldığı belirlenmiştir. Kadınların %8.5-10.6’sının bakımlarının ihmal edildiği, %3-9.3’ünün bakım alırken negatif ayrımcılığa uğradığı bildirilmiştir. Sonuç: Kadın yaşamının en özel dönemlerinden olan doğum sürecinde kadınların maruz kaldıkları obstetrik şiddet kavramı tanımlanmalı, bu şiddete karşı tüm sağlık profesyonelleri ortak bir hareketle mücadele etmelidirler.
Tıp fakültesi öğrencilerinin COVID-19 konusunda yaklaşımları ve sosyal medyanın rolü konusundaki düşünceleri
Authors: IŞIK Rabia , KONUŞ Süleyman , BAKAR Coşkun
Published: December 2021

Amaç: Bu araştırmada tıp fakültesi öğrencilerinin, COVID-19’a olan ilgilerindeki değişimin ve pandemiyle mücadelede sosyal medyanın rolü konusundaki düşüncelerinin tespit edilmesi amaçlanmıştır. Yöntem: Bu çalışma tanımlayıcı tipte bir epidemiyolojik araştırmadır. Çalışma internet ortamında uygulandığından evren ve örneklem belirlemesine gidilmemiştir. Araştırmaya katılan 388 kişiyi temsil etmektedir. Araştırmanın veri kaynağı olarak Google Formlar üzerinden 20 soruluk bir anket formu kullanılmıştır. Bulgular: Araştırmaya katılan 388 tıp fakültesi öğrencisinin %64.7’si kadındır. Katılımcıların yaş aralığı 17-29 olup %34’ü preklinik dönemde, %66’sı klinik dönemdedir. Katılımcıların COVID-19 ile ilgili en çok kullandığı bilgi kaynağı sosyal medya (%51), en güncel ve güvenilir olduğunu düşündükleri kaynak ise Dünya Sağlık Örgütü ve Sağlık Bakanlığı’nın web siteleridir (%48). Katılımcıların %98’i COVID-19’dan korunmak için tedbirlere uymanın gerekli olduğunu belirtirken %91’i sosyal medyadaki COVID-19 ile ilgili paylaşımlara olan ilgilerinin zaman içerisinde azaldığını ifade etmişlerdir. Hem COVID-19 bilgi düzeyinin yeterli olduğunu düşünen hem de COVID-19 olası vaka tanımındaki tüm semptomları bilenlerin, çalışmamıza katılan tüm tıp fakültesi öğrencileri içerisindeki oranının %28 olduğu görülmüştür. Sonuç: Bu araştırmanın sonuçlarının, mezun olduklarında sahada hizmet sunacak olan tıp fakültesi öğrencilerinin olağandışı durumlarda sağlık hizmeti sunumuyla ilgili ihtiyaç duyacakları eğitim programlarının oluşturulmasına yönelik katkı sağlayabileceği düşünülmektedir.
Obez bireylerde biyokimyasal parametreler istirahat enerji tüketimi ile ilişkili midir?
Authors: DAĞ Figen , GÜVENER Orhan , BÖLGEN ÇİMEN Özlem , TAMER Lülüfer , UYSAL Yücel
Published: December 2021

Stimulan Hormon (TSH) seviyeleri, kardiyo-metabolik etkileri olan lipit profili ve glukoz düzeyleri arasındaki ilişkinin araştırılmasıdır. Yöntem: Retrospektif olarak gerçekleştirilen bu çalışmaya yaş ortalaması 41.59±11.78 olan 76 birey katılmıştır. Dosya taraması yapılarak bireylere ait düşük dansiteli lipoprotein (LDL kolestrol), yüksek dansiteli lipoprotein (HDL kolestrol), total kolestrol, trigliserid, açlık kan glikozu ve TSH verileri kayıt edilmiştir. Bununla birlikte indirekt kalorimetri yöntemi ile tespit edilen İET verileri de analiz edilerek kkal/gün ve vücut ağırlığına göre normalize edilerek İET/kg olarak raporlanmıştır. İET değerlerinin, serum TSH, açlık glikoz düzeyi ve lipid profili ile ilişkisi incelendi. Bulgular: İET ile vücut kitle indeksi (VKİ) arasında pozitif yönlü zayıf-orta derecede bir korelasyon vardı (p=0.001, r=0.39). İET/kg ile VKİ arasında negatif yönlü orta derecede bir korelasyon saptandı. (p<0.001, r=-0.53). İET ile serum TSH düzeyleri arasında korelasyon saptanmadı. İET ile total kolesterol ve LDL arasında istatistiksel olarak anlamlı zayıf bir negatif yönlü bir korelasyon saptandı (p=0.006, r=-0.31 ve p=0.009, r=-0.3). İET/kg ile TSH, glukoz parametreleri arasında korelasyon gözlenmezken İET/kg ile total kolesterol ve LDL arasında istatistiksel olarak anlamlı zayıf bir negatif yönlü bir korelasyon vardı (p=0.007, r=-0.31 ve p=0.009, r=-0.3, sırasıyla). Sonuç: Kilolu ve obez bireylerde VKİ arttıkça İET artmaktayken İET ağırlığa göre normalize edildiğinde tam tersi bir eğilim gözlenmiştir. VKİ, İET, serum TSH, lipit parametreleri arasındaki ilişkiyi daha iyi anlayabilmek için iyi kurgulanmış prospektif çalışmalara ihtiyaç vardır.
Çocuk yaş grubunda nadir olarak görülen intravenöz port kateter komplikasyonu: Venobronşial fistül
Authors: İSBİR Caner , KILLI İsa , TAŞKINLAR Hakan , ESEN Kaan , NAYCI Ali
Published: December 2021

Cerrahi bir girişim ile ana venöz yapılara yerleştirilen, cilt altı rezervuarları ile kapalı bir sistem olan port kateterler çocuk hastalarda uzun süreli intravenöz tedavi ihtiyaçlarını karşılamak üzere giderek artan sıklıkta kullanılmaktadır. Nadir olarak görülen, vasküler erozyon ile gelişen, kateterin bulunduğu venin plevral veya perikardiyal alana açılması ile oluşan venobronşial fistüller, geç dönem port kateter komplikasyonları arasında yer almaktadır. Bu çalışmada, hemoptizi gibi sonuçlara yol açabilen, port kateter çekilmesi işlemini zorlaştıran, bu özellikleri ile hayati risk içeren bir komplikasyon olan venobronşial fistüllü bir olguyu sunmayı amaçladık.
Pediatrik hastalarda kolonoskopi bulgularının değerlendirilmesi; Tek merkez deneyimi
Authors: KARHAN Asuman , TUNCEL Ferah , USTA Yusuf
Published: December 2021

Amaç: Çalışmada, kolonoskopi yapılan çocuk hastalarda başvuru semptomları, işlem endikasyonları, sonuçlar ve komplikasyonların değerlendirilmesi amaçlandı. Yöntem: Çalışmaya Ocak 2008 ile Aralık 2020 tarihleri arasında kolonoskopi yapılan 0-18 yaş arası hastalar dahil edildi. Hastaların demografik özellikleri, kolonoskopi ve patoloji sonuçları geriye dönük incelendi. Bulgular: Çalışmaya dahil edilen 489 hastanın ortalama yaşı 12.39±4.32 yıl, %57.4’ü erkek, %42.6’sı kızdı. Hastaların 408’inde ≥1 semptom vardı. En sık üç semptom; rektal kanama (n=265, %54.1), karın ağrısı (n=187, %38.2) ve kanlı mukuslu dışkılamaydı (n=112, %22.9). Başlıca kolonoskopi endikasyonu inflamatuvar bağırsak hastalığı (İBH) şüphesi (n=212, %43.3), alt gastrointestinal sistemde kanama (n=145, %29.6) ve kronik ishaldi (n=59, %12). En sık iki tanı İBH (n=88, %17.9) ve polipti (n=31,%6.3). İnflamatuvar bağırsak hastalığı saptananların 46’sında (%9.4) ülseratif kolit, 32’sinde (%6.5) Crohn hastalığı ve 11’inde (%2.2) sınıflandırılamayan İBH olduğu belirlendi. Poliplerin en sık (%74.1) rektosigmoid kolonda yerleşim gösterdiği, %61.2’sinin juvenil polip olduğu saptandı. Sonuçları normal olan 272 (%55.6) hastada en sık iki semptomun rektal kanama (n=91, %62.7) ve ishal (n=31, %52.5), en sık bulgunun da anemi olduğu saptandı (n=25, %59.5). Karın ağrısıyla başvuran hastalarda, ek semptom varsa %30.6, ek semptom yoksa %62.9 oranında kolonoskopi sonucunun normal olduğu saptandı (p=0.032). İki hastada (%0.04) spontan perforasyon görüldü. Sonuç: Kolonoskopi doğru endikasyonla yapıldığında güvenilir bir yöntemidir. Özellikle karın ağrısıyla başvuran hastalarda, ek semptomların varlığı araştırılmalıdır. Çalışmamızda en sık saptanan hastalığın İBH olduğu ve sıklığın giderek artacağı öngörülmektedir ancak daha kesin sonuçlar için çok merkezli epidemiyolojik çalışmalara ihtiyaç vardır.
CAD/CAM ile üretilmiş PEEK ve PMMA ile geleneksel protez kaide materyallerinin bazı fiziksel özelliklerinin karşılaştırılması
Authors: ŞAHİN Zeynep , ERGUN Gulfem , ATAOL Ayşe Seda
Published: December 2021

Amaç: Bu çalışmanın amacı, CAD/CAM ile şekillendirilen kaide materyalleri (PMMA/PEEK) ve ısı ile polimerize olan geleneksel kaide materyalinin yüzey ve fiziksel özelliklerinin incelenmesidir. Yöntem: Bu çalışmada CAD/CAM ile frezelenmiş iki farklı kaide polimeri (Yamahachi PMMA Disk ve Juvora Dental Disk PEEK) ve bir adet ısı ile polimerize olan akrilik rezin (Meliodent PMMA) kullanıldı. Toplam 120 adet test örneği (n=10) hazırlandı. Test örneklerinin yarısı distile suda bekletildi. Diğer yarısına ise, termal döngü uygulandı. Termal döngüden sonra tüm test örneklerinin yüzey pürüzlülüğü, su emilimi ve çözünürlüğü değerlendirildi. Bulgular: CAD/CAM ile üretilen PMMA test örnekleri en düşük yüzey pürüzlülüğü değerleri (0.31±0.06 µm) göstermiştir. CAD/CAM ile üretilen PEEK grubu su emilimi açısından diğer iki grup test örneklerine göre istatistiksel olarak anlamlı daha düşük bulgular vermiştir (p<0.001). Termal döngü uygulaması test örneklerinin tümünün yüzey pürüzlülüğü, su emilimi ve çözünürlüğü değerlerini anlamlı derecede etkilememiştir (sırasıyla p=0.22; p=0.912; p=0.062). Sonuç: CAD/CAM ile üretilen PMMA ve PEEK materyalleri, ısı ile polimerize olan akrilik rezin test örnekleri ile kıyaslandığında daha iyi fiziksel özellikler göstermiştir.
The Existence of Radio Republik Indonesia Banda Aceh in Educating Disaster Risk Reduction Efforts
Authors: Maisarah Mila , Ismail Nazli , Munadi Khairul
Published: December 2021

Radio is one of the media still used by the public either for having entertainment or gaining information. Amid the rapid growth of television and internet, radio is still exhibiting its existence. Radio’s involvement on the efforts of educating Disaster Risk Reduction (DRR) to the public is crucial because it can be accessed conveniently in variety circumstances. This study focused on examining how the existence of Radio RepublikIndonesia (RRI) Banda Aceh in educating DRR efforts for the public. It discussed about how the people obtain the DRR education through some radio programs concerning to DRR. RRI Banda Aceh was chosen because it is the only one government owned radio in Banda Aceh that is responsible on educating the public through the broadcasting contents. This study was conducted by using a qualitative method. The data were collected by means of interviewing the leaders of RRI Banda Aceh and observing the recording of the radio broadcasted contents related to the DRR. This study, eventually, found that the existence of RRI Banda Aceh in educating DRR efforts was manifested in three different ways such as broadcasting disaster news, talk-shows, and public service announcements. Those three ways had their own advantages and disadvantages.