bluuebunny/crossref_metadata_2025 huggingface dataset:
Bactericidal Activity of Non-Cytotoxic Cationic Nanoparticles against Clinically and Environmentally Relevant Pseudomonas spp. Isolates
Authors: Schito Anna Maria , Piatti Gabriella , Caviglia Debora , Zuccari Guendalina , Zorzoli Alessia , Marimpietri Danilo , Alfei Silvana
Published: September 2021

Difficult-to-treat bacterial infections caused by resistant human and plant pathogens severely afflict hospitals, and concern the agri-food sectors. Bacteria from the Pseudomonadaceae family, such as P. aeruginosa, P. putida, P. fluorescens, and P. straminea, can be responsible for severe nosocomial infections in humans. P. fragi is the major cause of dairy and meat spoilage, while P. syringae can infect a wide range of economically important plant species, including tobacco, kiwi, and tomato. Therefore, a cationic water-soluble lysine dendrimer (G5-PDK) was tested on several species of Pseudomonas genus. Interestingly, G5-PDK demonstrated variable minimum inhibitory concentrations (MICs), depending on their pigment production, on Pseudomonas aeruginosa (1.6-> 6.4 µM), MICs = 3.2–6.4 µM on P. putida clinical isolates producing pyoverdine, and very low MICs (0.2–1.6 µM) on strains that produced non-pigmented colonies. Time-kill experiments established the rapid bactericidal activity of G5-PDK. In the cytotoxicity experiments on human keratinocytes, after 4 h of treatment with G5-PDK at concentrations 16–500 × MIC, more than 80% of viable cells were observed, and after 24 h, the selectivity indices were maintained above the maximum value reported as acceptable. Due to its proven bactericidal potency and low cytotoxicity, G5-PDK should be seriously considered to counteract clinically and environmentally relevant Pseudomonas isolates.
pH-Responsive Alginate-Based Microparticles for Colon-Targeted Delivery of Pure Cyclosporine A Crystals to Treat Ulcerative Colitis
Authors: Oshi Murtada A. , Lee Juho , Kim Jihyun , Hasan Nurhasni , Im Eunok , Jung Yunjin , Yoo Jin-Wook
Published: September 2021

Cyclosporine A (CsA) is a potent immunosuppressant for treating ulcerative colitis (UC). However, owing to severe systemic side effects, CsA application in UC therapy remains limited. Herein, a colon-targeted drug delivery system consisting of CsA crystals (CsAc)-loaded, Eudragit S 100 (ES)-coated alginate microparticles (CsAc-EAMPs) was established to minimize systemic side effects and enhance the therapeutic efficacy of CsA. Homogeneously-sized CsAs (3.1 ± 0.9 μm) were prepared by anti-solvent precipitation, followed by the fabrication of 47.1 ± 6.5 μm-sized CsAc-EAMPs via ionic gelation and ES coating. CsAc-EAMPs exhibited a high drug loading capacity (48 ± 5%) and a CsA encapsulation efficacy of 77 ± 9%. The in vitro drug release study revealed that CsA release from CsAc-EAMPs was suppressed under conditions simulating the stomach and small intestine, resulting in minimized systemic absorption and side effects. Following exposure to the simulated colon conditions, along with ES dissolution and disintegration of alginate microparticles, CsA was released from CsAc-EAMPs, exhibiting a sustained-release profile for up to 24 h after administration. Given the effective colonic delivery of CsA molecules, CsAc-EAMPs conferred enhanced anti-inflammatory activity in mouse model of dextran sulfate sodium (DSS)-induced colitis. These findings suggest that CsAc-EAMPs is a promising drug delivery system for treating UC.
Silane Modification of Mesoporous Materials for the Optimization of Antiviral Drug Adsorption and Release Capabilities in Vaginal Media
Authors: Whittle Elena , Martín-Illana Araceli , Cazorla-Luna Raul , Notario-Perez Fernando , Veiga-Ochoa María Dolores , Rubio Juan , Tamayo Aitana
Published: September 2021

Three different functionalities have been incorporated into mesoporous materials by means of a coupling reaction with the siloxanes 3-glycidoxypropyl-trimethoxysilane (GLYMO), 3-methacryloxypropyl-trimethoxysilane (MEMO), and 3-mercaptopropyl-trimethoxysilane (MPTMS). The disposition of the different functional groups, as well as the interaction mechanism, with the mesoporous substrate has been identified. The amount of the antiviral drug acyclovir (ACV) adsorbed depends not only on the available surface area but also on the chemical or physicochemical interactions between functionalities. The drug adsorption isotherm of the materials functionalized with GLYMO and MPTMS follow mechanisms dependent on the different surface coverage and the possibilities to establish physicochemical interactions between the drug molecule and the functionalities. On the contrary, when functionalizing with MEMO, the dominant adsorption mechanism is characteristic of chemically bonded adsorbates. The ACV release kinetics is best fitted to the Weibull model in all the functionalized materials. When the MTPMS is used as a functionalizing agent, the drug diffusion occurs at low kinetics and homogeneously along the mesoporous channels.
The Repurposing of the Antimalaria Drug, Primaquine, as a Photosensitizer to Inactivate Cryptococcal Cells
Authors: Madu Uju L. , Ogundeji Adepemi O. , Folorunso Olufemi S. , Albertyn Jacobus , Pohl Carolina H. , Sebolai Olihile M.
Published: September 2021

Cryptococcal cells can manifest skin infections in immunocompromised persons. While it may be easy to diagnose cryptococcal infection, treatment often fails due to the ineffectiveness of current antifungal agents. To this end, the present study explored the repurposing of primaquine (PQ), as a photosensitizer. PDT was carried out using a germicidal ultraviolet (UV) lamp, which has a radiation output of approximately 625 µW/cm2 at a distance of 20 cm. When compared to the non-treated cells, the metabolic activity of cryptococcal cells was significantly (p < 0.05) limited. The photolytic products of PQ were observed to alter the ultrastructure of treated cells. The latter was not incidental, as the same cells were also documented to lose their selective permeability. Importantly, PDT also improved the efficiency of macrophages to kill internalized cryptococcal cells (p ≤ 0.05) when compared to non-treated macrophages. Equally importantly, PDT was not detrimental to macrophages, as their metabolic activity was not significantly (p > 0.05) limited, even when exposed to 20× the MIC (determined for cryptococcal cells) and an exposure time that was 4× longer. Taken together, the results suggest PQ has the potential to control the growth of cryptococcal cells and limit their survival inside the macrophage.
Macromolecular Design for Oxygen/Nitrogen Permselective Membranes—Top-Performing Polymers in 2020—
Authors: Wang Jianjun , Shi Zhichun , Zang Yu , Jia Hongge , Teraguchi Masahiro , Kaneko Takashi , Aoki Toshiki
Published: September 2021

Oxygen/nitrogen permselective membranes play particularly important roles in fundamental scientific studies and in a number of applications in industrial chemistry, but have not yet fulfilled their full potential. Organic polymers are the main materials used for such membranes because of the possibility of using sophisticated techniques of precise molecular design and their ready processability for making thin and large self-supporting membranes. However, since the difference in the properties of oxygen and nitrogen gas molecules is quite small, for example, their kinetic diameters are 3.46 Å and 3.64 Å, respectively, the architectures of the membrane macromolecules should be designed precisely. It has been reported often that oxygen permeability (PO2) and oxygen permselectivity (α = PO2/PN2) have trade-off relationships for symmetric membranes made from pure polymers. Some empirical upper bound lines have been reported in (ln α − ln PO2) plots since Robeson reported an upper bound line in 1991 for the first time. The main purpose of this review is to discuss suitable macromolecular structures that produce excellent oxygen/nitrogen permselective membranes. For this purpose, we first searched extensively and intensively for papers which had reported α and PO2 values through symmetric dense membranes from pure polymers. Then, we examined the chemical structures of the polymers showing the top performances in (ln α − ln PO2) plots, using their aged performances. Furthermore, we also explored progress in the molecular design in this field by comparing the best polymers reported by 2013 and those subsequently found up to now (2020) because of the rapid outstanding growth in this period. Finally, we discussed how to improve α and PO2 simultaneously on the basis of reported results using not only symmetric membranes of pure organic polymers but also composite asymmetric membranes containing various additives.
Analysis of the Effect of Parameters on Fracture Toughness of Hemp Fiber Reinforced Hybrid Composites Using the ANOVA Method
Authors: Madhusudhana H. K. , Kumar M. Prasanna , Patil Arun Y. , Keshavamurthy R. , Khan T. M. Yunus , Badruddin Irfan Anjum , Kamangar Sarfaraz
Published: September 2021

In today’s world, global warming has become a concern. To overcome this, we need to reduce the carbon footprints caused by the production of materials. Much of the time, this is equivalent to the same amount of CO2 emissions per tonne of production. This is a serious concern and needs to be overcome by identifying alternative materials to have as minimal a carbon footprint as possible. In this context, hemp fiber is by far the best natural fiber when compared to its peers. As per the survey conducted by the Nova institute, hemp has CO2 emissions of only 360 Kg/tonne, whereas jute has CO2 emissions of 550 Kg/tonne, kenaf 420 Kg/tonne, and flax 350 Kg/tonne. This paper presents an experimental study of the fracture toughness of hemp-reinforced hybrid composites (HRHC). The effect of the parameters on the fracture toughness behavior of HRHC is studied using the Taguchi technique. It uses different filler combinations with hemp fiber and epoxy. Hemp fiber is used as the reinforcement, epoxy resin is used as a matrix, and banana fiber, coconut shell powder, and sawdust are used as fillers. The experimental plan is prepared using an orthogonal array and analyzed using Minitab software. The obtained results were analyzed using ANOVA and main effects plots. It was observed that the fracture toughness increases with a decrease in thickness. The fracture toughness is affected by the fiber content in the range of 25%–35% and is also affected by the filler materials.
Determination of Fire Parameters of Polyamide 12 Powder for Additive Technologies
Authors: Kuracina Richard , Szabová Zuzana , Buranská Eva , Pastierová Alica , Gogola Peter , Buranský Ivan
Published: September 2021

The use of additive technologies keeps growing. Increasingly, flammable powder materials are also used in additive technologies, and there is a risk of explosion or fire when using them. The current article deals with the determination of fire parameters of a powder sample of polyamide Sinterit PA12 Smoth in accordance with the EN 14034 and EN ISO/IEC 80079-20-2 standards. For that purpose, a sample at a median size of 27.5 µm and a humidity of 0% wt. was used. The measurements showed that the maximum explosion pressure of the PA12 polyamide sample was 6.78 bar and the value of the explosion constant Kst was 112.2 bar·m·s−1. It was not possible to determine the MIT value of the settled dust, since the melting point of polyamide sample is low. The MIT of the dispersed dust was 450 °C. Based on the measured results, it can be stated that the powdered polyamide PA12 poses a risk in terms of explosions and fires. Therefore, when using polyamide PA12 in additive technologies, it is necessary to ensure an effective explosion prevention.
Antioxidant Potential of the Bio-Based Fucose-Rich Polysaccharide FucoPol Supports Its Use in Oxidative Stress-Inducing Systems
Authors: Guerreiro Bruno , Silva Jorge , Lima João , Reis Maria , Freitas Filomena
Published: September 2021

Reactive oxygen species (ROS) are dangerous sources of macromolecular damage. While most derive from mitochondrial oxidative phosphorylation, their production can be triggered by exogenous stresses, surpassing the extinction capacity of intrinsic antioxidant defense systems of cells. Here, we report the antioxidant activity of FucoPol, a fucose-rich polyanionic polysaccharide produced by Enterobacter A47, containing ca. 17 wt% of negatively charged residues in its structure. Ferric reducing antioxidant power (FRAP) assays coupled to Hill binding kinetics fitting have shown FucoPol can neutralize ferricyanide and Fe3+-TPTZ species at an EC50 of 896 and 602 µg/mL, respectively, with positive binding cooperativity (2.52 ≤ H ≤ 4.85). This reducing power is greater than most polysaccharides reported. Moreover, an optimal 0.25% w/v FucoPol concentration shown previously to be cryo- and photoprotective was also demonstrated to protect Vero cells against H2O2-induced acute exposure not only by attenuating metabolic viability decay, but also by accentuating post-stress proliferation capacity, whilst preserving cell morphology. These results on antioxidant activity provide evidence for the biopolymer’s ability to prevent positive feedback cascades of the radical-producing Fenton reaction. Ultimately, FucoPol provides a biotechnological alternative for implementation in cryopreservation, food supplementation, and photoprotective sunscreen formula design, as all fields benefit from an antioxidant functionality.
Evaluation and Characterization of Tamarind Gum Polysaccharide: The Biopolymer
Authors: Malviya Rishabha , Sundram Sonali , Fuloria Shivkanya , Subramaniyan Vetriselvan , Sathasivam Kathiresan V. , Azad Abul Kalam , Sekar Mahendran , Kumar Darnal Hari , Chakravarthi Srikumar , Porwal Omji , Meenakshi Dhanalekshmi Unnikrishnan , Fuloria Neeraj Kumar
Published: September 2021

Polymers from natural sources are widely used as excipients in the formulation of pharmaceutical dosage forms. The objective of this study was to extract and further characterize the tamarind gum polysaccharide (TGP) obtained from Tamarindus indica as an excipient for biomedical applications. Double distilled water was used as a solvent for the extraction of gum while Ethyl alcohol was used as an antisolvent for the precipitation. The results of the Hausner ratio, Carr’s index and angle of repose were found to be 0.94, 6.25, and 0.14, respectively, which revealed that the powder is free-flowing with good flowability. The gum was investigated for purity by carrying out chemical tests for different phytochemical constituents and only carbohydrates were found to be present. The swelling index was found to be 87 ± 1%, which shows that TGP has good water intake capacity. The pH of the 1% gum solution was found to be neutral, approximately 6.70 ± 0.01. The ash values such as total ash, sulphated ash, acid insoluble ash, and water-soluble ash were found to be 14.00 ± 1.00%, 13.00 ± 0.05%, 14.04 ± 0.57% and 7.29 ± 0.06%, respectively. The IR spectra confirmed the presence of alcohol, amines, ketones, anhydrides groups. The contact angle was <90°, indicating favorable wetting and good spreading of liquid over the surface The scanning electron micrograph (SEM) revealed that the particle is spherical in shape and irregular. DSC analysis shows a sharp exothermic peak at 350 °C that shows its crystalline nature. The results of the evaluated properties showed that TGP has acceptable properties and can be used as a excipient to formulate dosage forms for biomedical applications.
Prevention of Depression in Children, Adolescents, and Young Adults: The Role of Teachers and Parents
Authors: Del Casale Antonio , Zocchi Clarissa , Kotzalidis Georgios D. , Fiaschè Federica , Girardi Paolo
Published: September 2021

Major depressive disorder (MDD) and other affective disorders may surreptitiously arise in children and adolescents during their school period and impair their social and educational functioning. Besides the social and personal burden, which are increased during the SARS-CoV-2 pandemic, the onset of depression may compromise the future of the growing person with chronicity and recurrence. In this context, educators’ training is essential to detect early the onset of a depressive disorder, to spare later consequences through the timely establishment of adequate treatment. The educational staff should receive adequate training to be able to work closely with healthcare providers and parents, thus directing the young person with an affective disorder to the right psychological and pharmacological treatment provider, i.e., a specialized psychologist or psychiatrist. The first approach should be to establish a trustful relationship with the adolescent and his/her classmates, to reduce social and self-stigma and inform about mental illness. If symptoms do not subside and the suffering child or adolescent fails to reintegrate within his/her school environment, cognitive–behavioral interventions are recommended that are individual, group, or computer-based. When needed, these should be implemented with individualized pharmacotherapy.
The Feminine in the Poetry of Yunus Emre: A Case Study in the Hierophanic Dialectics of Mystical Islamic Experience
Authors: Adrahtas Vassilios
Published: September 2021

This article is about the most important Turkish Sufi poet and, more specifically, about the presence and the pragmatics of ‘the Feminine’ in his experience—inasmuch as the latter is reflected in his work. To be sure, this is a case study, in the sense that it aspires to provide only an idea as to how ‘the Feminine’ pervades Sufi hierophanics/religion, and also in the sense that it does not assume to be a comprehensive and exhaustive discussion—not even of Yunus Emre himself. Select(ed) poems of Yunus Emre are explored in the methodological light of what Mircea Eliade has dubbed ‘hierophanic dialectics’, and what Catherine Clément and Julia Kristeva regard as ‘the Feminine’ in relation to the sacred/religious from the perspective of social anthropology and psychoanalysis. In the poetry of Yunus Emre ‘the Feminine’ turns out to be the subtle yet decisive challenge, opposition, and subversion that, on the one hand, negates symbolic Islam and, on the other, affirms imaginary Islam in the name of the Islamic real—to evoke the terminology of Jacques Lacan.
Teilhard’s Catholicity: An Evolution of Consciousness
Authors: Del Rossi Andrew
Published: September 2021

Pierre Teilhard de Chardin, Jesuit mystic and scientist, was a groundbreaking thinker whose synthesis of evolution and faith challenges the faithful to see God in a more expansive perspective. Teilhard’s vision ultimately posits that the universe is evolving closer in relationship with the Divine. Through the increase in material complexity and consciousness, the spiritual power of the cosmos is revealed, identified by Teilhard as becoming personalized in the Cosmic Christ. This article uses the four marks of the Catholic Church—one, holy, universal, and apostolic—to highlight the catholicity, or universality, of Teilhard’s life and vision and its relevance for seekers who probe for God’s presence in all things.
Introduction to “Spanish Mysticism”
Authors: Serrán-Pagán y Fuentes Cristóbal
Published: September 2021

As the Guest Editor for the special volume on “Spanish Mysticism”, my experience working with experts in this field has been excellent and very rewarding, especially in these current times, where we are dealing with COVID-19 [...]
A Comparison of ALS and Dense Photogrammetric Point Clouds for Individual Tree Detection in Radiata Pine Plantations
Authors: Iqbal Irfan A. , Osborn Jon , Stone Christine , Lucieer Arko
Published: September 2021

Digital aerial photogrammetry (DAP) has emerged as a potentially cost-effective alternative to airborne laser scanning (ALS) for forest inventory methods that employ point cloud data. Forest inventory derived from DAP using area-based methods has been shown to achieve accuracy similar to that of ALS data. At the tree level, individual tree detection (ITD) algorithms have been developed to detect and/or delineate individual trees either from ALS point cloud data or from ALS- or DAP-based canopy height models. An examination of the application of ITDs to DAP-based point clouds has not yet been reported. In this research, we evaluate the suitability of DAP-based point clouds for individual tree detection in the Pinus radiata plantation. Two ITD algorithms designed to work with point cloud data are applied to dense point clouds generated from small- and medium-format photography and to an ALS point cloud. Performance of the two ITD algorithms, the influence of stand structure on tree detection rates, and the relationship between tree detection rates and canopy structural metrics are investigated. Overall, we show that there is a good agreement between ALS- and DAP-based ITD results (proportion of false negatives for ALS, SFP, and MFP was always lower than 29.6%, 25.3%, and 28.6%, respectively, whereas, the proportion of false positives for ALS, SFP, and MFP was always lower than 39.4%, 30.7%, and 33.7%, respectively). Differences between small- and medium-format DAP results were minor (for SFP and MFP, differences between recall, precision, and F-score were always less than 0.08, 0.03, and 0.05, respectively), suggesting that DAP point cloud data is robust for ITD. Our results show that among all the canopy structural metrics, the number of trees per hectare has the greatest influence on the tree detection rates.
Security, Privacy, and Usability in Continuous Authentication: A Survey
Authors: Baig Ahmed Fraz , Eskeland Sigurd
Published: September 2021

Continuous authentication has been proposed as a possible approach for passive and seamless user authentication, using sensor data comprising biometric, behavioral, and context-oriented characteristics. Since these are personal data being transmitted and are outside the control of the user, this approach causes privacy issues. Continuous authentication has security challenges concerning poor matching rates and susceptibility of replay attacks. The security issues are mainly poor matching rates and the problems of replay attacks. In this survey, we present an overview of continuous authentication and comprehensively discusses its different modes, and issues that these modes have related to security, privacy, and usability. A comparison of privacy-preserving approaches dealing with the privacy issues is provided, and lastly recommendations for secure, privacy-preserving, and user-friendly continuous authentication.
A Novel Tool for Gait Analysis: Validation Study of the Smart Insole PODOSmart®
Authors: Ziagkas Efthymios , Loukovitis Andreas , Zekakos Dimitrios Xypolias , Chau Thomas Duc-Phu , Petrelis Alexandros , Grouios George
Published: September 2021

The new smart insole PODOSmart®, is introduced as a new tool for gait analysis against high cost laboratory based equipment. PODOSmart® system measures walking profile and gait variables in real life conditions. PODOSmart® insoles consists of wireless sensors, can be fitted into any shoe and offer the ability to measure spatial, temporal, and kinematic gait parameters. The intelligent insoles feature several sensors that detect and capture foot movements and a microprocessor that calculates gait related biomechanical data. Gait analysis results are presented in PODOSmart® platform. This study aims to present the characteristics of this tool and to validate it comparing with a stereophotogrammetry-based system. Validation was performed by gait analysis for eleven healthy individuals on a six-meters walkway using both PODOSmart® and Vicon system. Intraclass correlation coefficients (ICC) were calculated for gait parameters. ICC for the validation ranged from 0.313 to 0.990 in gait parameters. The highest ICC was observed in cadence, circumduction, walking speed, stride length and stride duration. PODOSmart® is a valid tool for gait analysis compared to the gold standard Vicon. As PODOSmart®, is a portable gait analysis tool with an affordable cost it can be a useful novel tool for gait analysis in healthy and pathological population.
Mask Attention-SRGAN for Mobile Sensing Networks
Authors: Huang Chi-En , Chang Ching-Chun , Li Yung-Hui
Published: September 2021

Biometrics has been shown to be an effective solution for the identity recognition problem, and iris recognition, as well as face recognition, are accurate biometric modalities, among others. The higher resolution inside the crucial region reveals details of the physiological characteristics which provides discriminative information to achieve extremely high recognition rate. Due to the growing needs for the IoT device in various applications, the image sensor is gradually integrated in the IoT device to decrease the cost, and low-cost image sensors may be preferable than high-cost ones. However, low-cost image sensors may not satisfy the minimum requirement of the resolution, which definitely leads to the decrease of the recognition accuracy. Therefore, how to maintain high accuracy for biometric systems without using expensive high-cost image sensors in mobile sensing networks becomes an interesting and important issue. In this paper, we proposed MA-SRGAN, a single image super-resolution (SISR) algorithm, based on the mask-attention mechanism used in Generative Adversarial Network (GAN). We modified the latest state-of-the-art (nESRGAN+) in the GAN-based SR model by adding an extra part of a discriminator with an additional loss term to force the GAN to pay more attention within the region of interest (ROI). The experiments were performed on the CASIA-Thousand-v4 dataset and the Celeb Attribute dataset. The experimental results show that the proposed method successfully learns the details of features inside the crucial region by enhancing the recognition accuracies after image super-resolution (SR).
Kinematics Adaptation and Inter-Limb Symmetry during Gait in Obese Adults
Authors: Pau Massimiliano , Capodaglio Paolo , Leban Bruno , Porta Micaela , Galli Manuela , Cimolin Veronica
Published: September 2021

The main purpose of this study is to characterize lower limb joint kinematics during gait in obese individuals by analyzing inter-limb symmetry and angular trends of lower limb joints during walking. To this purpose, 26 obese individuals (mean age 28.5 years) and 26 normal-weight age- and sex-matched were tested using 3D gait analysis. Raw kinematic data were processed to derive joint-specific angle trends and angle-angle diagrams (synchronized cyclograms) which were characterized in terms of area, orientation and trend symmetry parameters. The results show that obese individuals exhibit a kinematic pattern which significantly differs from those of normal weight especially in the stance phase. In terms of inter-limb symmetry, higher values were found in obese individuals for all the considered parameters, even though the statistical significance was detected only in the case of trend symmetry index at ankle joint. The described alterations of gait kinematics in the obese individuals and especially the results on gait asymmetry are important, because the cyclic uneven movement repeated for hours daily can involve asymmetrical spine loading and cause lumbar pain and could be dangerous for overweight individuals.
Periodic Tubular Structures and Phononic Crystals towards High-Q Liquid Ultrasonic Inline Sensors for Pipes
Authors: Mukhin Nikolay , Lucklum Ralf
Published: September 2021

The article focuses on a high-resolution ultrasound sensor for real-time monitoring of liquid analytes in cylindrical pipes, tubes, or capillaries. The development of such a sensor faces the challenges of acoustic energy losses, including dissipation at liquid/solid interface and acoustic wave radiation along the pipe. Furthermore, we consider acoustic resonant mode coupling and mode conversion. We show how the concept of phononic crystals can be applied to solve these problems and achieve the maximum theoretically possible Q-factor for resonant ultrasonic sensors. We propose an approach for excitation and measurement of an isolated radial resonant mode with minimal internal losses. The acoustic energy is effectively localized in a narrow probing area due to the introduction of periodically arranged sectioned rings around the tube. We present a sensor design concept, which optimizes the coupling between the tubular resonator and external piezoelectric transducers. We introduce a 2D-phononic crystal in the probing region for this purpose. The Q-factor of the proposed structures show the high prospects for phononic crystal pipe sensors.
Investigation of Deformation Pattern and Movement Law of the Huge-Thick Conglomerate Stratum by a Large-Scale 3D Model Test with Distributed Optical Fiber Sensor Monitoring
Authors: Yuan Qiang , Chai Jing , Zhang Yuzhu , Liu Yongliang , Ren Yiwei
Published: September 2021

Mining activities under the circumstances of huge-thick stratum occurrence commonly result in dynamic response of the working face. It is crucial to understand the rock failure and movement of the huge-thick stratum in order to prevent dynamic hazards. This paper introduces distributed optical fiber sensor (DOFS) monitoring into a large-scale model test to investigate the deformation pattern and movement law of the huge-thick conglomerate (HTC); the monitoring results are verified by numerical simulation. The results indicate that DOFS monitoring captures the spatiotemporal evolution of zoning development in the overburden deformation. The deformation field of HTC is illustrated, and there exists a strain basin that can be used to estimate the movement law of HTC. The average strain variability Ex, a new homogenization index for characterizing the overburden deformation, is proposed to describe the broken rules of the HTC. The numerical simulation proves the feasibility of the DOFS monitoring method and the correctness of the deformation pattern and movement law. This study provides efficient methods for DOFS monitoring utilization to investigate mining engineering problems and could be beneficial for unearthing the mechanisms of deep ground rock deformation.
Individual’s Social Perception of Virtual Avatars Embodied with Their Habitual Facial Expressions and Facial Appearance
Authors: Park Sung , Kim Si Pyoung , Whang Mincheol
Published: September 2021

With the prevalence of virtual avatars and the recent emergence of metaverse technology, there has been an increase in users who express their identity through an avatar. The research community focused on improving the realistic expressions and non-verbal communication channels of virtual characters to create a more customized experience. However, there is a lack in the understanding of how avatars can embody a user’s signature expressions (i.e., user’s habitual facial expressions and facial appearance) that would provide an individualized experience. Our study focused on identifying elements that may affect the user’s social perception (similarity, familiarity, attraction, liking, and involvement) of customized virtual avatars engineered considering the user’s facial characteristics. We evaluated the participant’s subjective appraisal of avatars that embodied the participant’s habitual facial expressions or facial appearance. Results indicated that participants felt that the avatar that embodied their habitual expressions was more similar to them than the avatar that did not. Furthermore, participants felt that the avatar that embodied their appearance was more familiar than the avatar that did not. Designers should be mindful about how people perceive individuated virtual avatars in order to accurately represent the user’s identity and help users relate to their avatar.
Enhanced Lead Phytoextraction by Endophytes from Indigenous Plants
Authors: Pietrini Ilaria , Grifoni Martina , Franchi Elisabetta , Cardaci Anna , Pedron Francesca , Barbafieri Meri , Petruzzelli Gianniantonio , Vocciante Marco
Published: September 2021

Lead (Pb) is one of the most common metal pollutants in soil, and phytoextraction is a sustainable and cost-effective way to remove it. The purpose of this work was to develop a phytoextraction strategy able to efficiently remove Pb from the soil of a decommissioned fuel depot located in Italy by the combined use of EDTA and endophytic bacteria isolated from indigenous plants. A total of 12 endophytic strains from three native species (Lotus cornicolatus, Sonchus tenerrimus, Bromus sterilis) were isolated and selected to prepare a microbial consortium used to inoculate microcosms of Brassica juncea and Helianthus annuus. As for B. juncea, experimental data showed that treatment with microbial inoculum alone was the most effective in improving Pb phytoextraction in shoots (up to 25 times more than the control). In H. annuus, on the other hand, the most effective treatment was the combined treatment (EDTA and inoculum) with up to three times more Pb uptake values. These results, also validated by the metagenomic analysis, confirm that plant-microbe interaction is a crucial key point in phytoremediation.
Embedded Resistance Wire Technique for Epoxy Curing and Self-Healing of PET Thermoplastics
Authors: Kontaxis Lykourgos C. , Kotrotsos Athanasios , Verbis Spyros , Papanicolaou George C.
Published: September 2021

The aim of the present study is to apply an embedded resistance wire technique for curing of thermosetting resins as well as for the self-healing of thermoplastic polymers. The work consists of two parts. In the first part, Kanthal resistance wires embedded in a resin plate acted as heating elements when direct electrical current was flowing through them (Joule heating). During heating, the temperature was continuously monitored using a thermal camera, and accurate temperature times for fixed position diagrams as well as temperature positions for fixed time diagrams were calculated. The effects of curing with this method were evaluated by studying the three-point bending mechanical behavior of the cured resin, comparing it with the corresponding behavior of the same resin when cured using a conventional oven curing method at the same temperature. In the second part of the present work, the possibility of using the same technique for healing existing notches and flaws in a PET thermoplastic is explored. We examined whether providing energy through the resistance wires created the right amount of heat to heal the thermoplastic, or, more specifically, whether it closed the notches and eliminated the abrasions that were artificially created on the specimens. The technique using embedded resistance wires worked equally well, with interesting and promising preliminary results regarding the curing of thermoset resins and the healing of thermoplastics.
Effects of Paracetamol (Acetaminophen) Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis
Authors: Grgic Jozo , Mikulic Pavle
Published: September 2021

Several studies explored the effects of paracetamol (acetaminophen) ingestion on endurance performance, but their findings are conflicting. Therefore, this review aimed to conduct a meta-analysis examining the effects of paracetamol ingestion on endurance performance. Five databases were searched to find relevant studies. The PEDro checklist was used to assess the methodological quality of the included studies. Data reported in the included studies were pooled in a random-effects meta-analysis. A total of ten studies with good or excellent methodological quality were included in the meta-analysis (pooled n = 141). All included studies had a randomized, double-blind, crossover design. In the main meta-analysis, there was no significant difference between the effects of placebo and paracetamol on endurance performance (Cohen’s d = 0.09; 95% confidence interval (CI): −0.04, 0.22; p = 0.172). However, an ergogenic effect was found when we considered only the studies that provided paracetamol 45 to 60 min before exercise (Cohen’s d = 0.14; 95% CI: 0.07, 0.21; p < 0.001). In a subgroup analysis that focused on time-to-exhaustion tests, there was a significant ergogenic effect of paracetamol ingestion (Cohen’s d = 0.19; 95% CI: 0.06, 0.33; p = 0.006). There was no significant difference between placebo and paracetamol in a subgroup analysis that focused on time trial tests (Cohen’s d = 0.05; 95% CI: −0.12, 0.21; p = 0.561). In conclusion, paracetamol ingestion appears to enhance performance (a) in time-to-exhaustion endurance tests and (b) when consumed 45 to 60 min before exercise.
Explainable Ontology-Based Intelligent Decision Support System for Business Model Design and Sustainability
Authors: Hamrouni Basma , Bourouis Abdelhabib , Korichi Ahmed , Brahmi Mohsen
Published: September 2021

Background: Case-Based Reasoning (CBR) is a problem-solving paradigm that uses knowledge of relevant past experiences (cases) to interpret or solve new problems. CBR systems allow generating explanations easily, as they typically organize and represent knowledge in a way that makes it possible to reason about and thereby generate explanations. An improvement of this paradigm is ontology-based CBR, an approach that combines, in the form of formal ontologies, case-specific knowledge with domain one in order to improve the effectiveness and explanation capability of the system. Intelligent systems make daily activities more easily, efficiently, and represent a real support for sustainable economic development. On the one hand, they improve efficiency, productivity, and quality, and, on the other hand, can reduce costs and cut waste. In this way, intelligent systems facilitate sustainable development, economic growth, societal progress, and improve efficiency. Aim: In this vision, the purpose of this paper is to propose a new generation of intelligent decision support systems for Business Model having the ability to provide explanations to increase confidence in proposed solutions. Findings/result: The performance results obtained show the benefits of the proposed solution with different requirements of an explanatory decision support system. Consequently, applying this paradigm for software tools of business model development will make a great promise for supporting business model design, sustainability, and innovation.
Analyzing the Characteristics and Evolution of Chinese Enterprises’ Outward Forward Direct Investment Host Country Network
Authors: Zhang Xiaoling , Tang Decai , Bethel Brandon J.
Published: September 2021

With the promulgation of the “Going Global” strategy, Chinese enterprises’ outward forward direct investment (OFDI) moved towards a stage of rapid development. Based on the data concerning projects of Chinese enterprises, this paper establishes a network of OFDI host countries with the industry as the media and analyzes the network and its evolution characteristics by using the complex network method. Results show that the number of network nodes is increasing, and the edges between communities are greater, and the number of countries along the Belt and Road route is increasing. The network is a so-called small-world network. To reduce investment risks, it is necessary to identify the key nodes in the network. Based on the centrality of key nodes in complex networks, the improved “scatter degree” method is used to evaluate the importance of each host node. Results demonstrate that the United States and Australia are the most important countries for Chinese enterprises to invest overseas, followed by Brazil, Canada, Russia, Indonesia, and the United Kingdom (UK). Excluding the UK, all other countries are resource-rich. Thus, it can be seen that the FDI of Chinese enterprises is mainly resource-based investment.
A Systematic Review of Digital Storytelling in Improving Speaking Skills
Authors: Nair Viknesh , Yunus Melor Md
Published: September 2021

Educational systems frequently employ technological equipment in a variety of ways to make lessons in an English Language classroom fun and meaningful. For both students and instructors, digital storytelling (DST) has evolved into a useful instructional tool that can be utilised in the teaching and learning process. To answer the research question on the role of digital storytelling in improving students’ speaking skills, The Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) was used to systematically review 45 articles sourced from Google scholar and ERIC, and most of these articles highlight the importance of digital storytelling as a contemporary teaching methodology. These articles showed that digital storytelling can be used as a useful tool by educators in improving students’ speaking skills from various levels of education, ranging from primary to tertiary education. Most of the authors of these research papers provided empirical proof that substantiated the advantages of employing digital storytelling in the classroom to help pupils communicate and speak more effectively.
A Gender-Focused Prism on the Long-Term Impact of Teachers’ Emotional Mistreatment on Resilience: Do Men and Women Differ in Their Quest for Social-Emotional Resources in a Masculine Society?
Authors: Dolev Niva , Itzkovich Yariv , Katzman Bat
Published: September 2021

As a personal resource, resilience enables individuals to cope with stressful life events and to adapt to diverse situations. In the framework of Conservation of Resource (COR) theory, the current study investigates whether personal and social resources, namely emotional intelligence (EI) and gender, can contribute to resilience for individuals who experienced teacher mistreatment as adolescents. Our findings show that men and women differ in their baselines concerning mistreatment and emotional intelligence. Individual resources in the form of EI and social resources, and particularly gender, affect resilience. Moreover, gender and the Use of Emotion (UOE) facet of EI interact in their contribution to resilience. These findings provide better insights into the interrelationships between the diverse resources affected by past teacher mistreatment. An enhanced understanding can help us mitigate teacher mistreatment and promote more socially sustainable communities that are just and equitable, and support the emotional and social growth and resilience of its members
Heritage Sustainability of the Territory: Photogrammetric Survey of the Castle of Beas de Segura (Jaén, Spain)
Authors: Millán-Millán Pablo Manuel , Fernández-Cuadros José Miguel
Published: September 2021

Beas de Segura is an ancient village located in the valley of the Sierra de Segura, at the gateway to the Sierra de Cazorla, Segura y las Villas (Jaén, Spain). This territory has been inhabited by different cultures, from the Palaeolithic to the present day, giving rise to a complex urban fabric in which relevant architectural and archaeological elements still survive. The coexistence of these heritage structures with the inhabited domestic architecture has generated significant conflicts of coexistence, resulting in an accelerated process of physical and social deterioration of this increasingly impoverished area. Drawing, together with all the techniques that derive from it, is a necessary and precise source of knowledge and communication for understanding the territory, however complex it may be. This potential, applied to a heritage and social reality such as that of the Castle and Fortress of Beas de Segura (Jaén), allows for processes to be revealed, actions to be ordered, and interventions to be proposed. This article brings together the results of research carried out in this area of the Sierra de Segura, in which graphic expression, combined with the study of materials, has enabled us to identify original elements of the castle and medieval fortification. This system of knowledge discovery has been decisive in establishing a criterion for heritage intervention, seeking a sustainable balance between the development of life in this area of the city, the recovery of the collective memory of the surviving elements of the castle and fortress, and the conservation of the protected historical remains.
Effects of Controlled Drainage on the Content Change and Migration of Moisture, Nutrients, and Salts in Soil and the Yield of Oilseed Sunflower in the Hetao Irrigation District
Authors: Dou Xu , Shi Haibin , Li Ruiping , Miao Qingfeng , Tian Feng , Yu Dandan , Zhou Liying , Wang Bo
Published: September 2021

Controlled drainage (CD) is an important agricultural measure for maintaining soil moisture and nutrients, controlling groundwater level, and increasing crop yield. In arid regions, CD can be used to improve the water supply in agriculture and reduce environmental pollution. In this study, we investigated the effects of CD, including drainage depths of 40 cm (CWT1) and 70 cm (CWT2) during the plant growth stages, free drainage (FD), and open-ditch drainage (OD), on the migration of water, nutrients, and salts in the soil, the dynamics of the groundwater level, the loss of soil nitrogen, and the growth of oilseed sunflower plants. Compared with FD, CD increased the water and nutrient content in the soil, reduced nitrogen loss, and enhanced the ability of the soil to continuously supply nitrogen to the oilseed sunflower plants, which benefited plant growth at later growth stages and reduced environmental pollution. During the period between irrigation at the budding stage and the harvest stage, the average soil water content in the 0–20 cm soil layer in CWT1 increased by 3.67%, 4.78%, and 0.55%, respectively, compared with that in CWT2, FD, and OD. The soil mineral content in CWT1 was 25.17%, 35.05%, and 17.78% higher than that in CWT2, FD, and OD, respectively, indicating that higher soil salinity occurred at the later stage of plant growth in CWT1, which actually had little effect on the plants due to their enhanced salt tolerance and increased need for water and nutrients at that stage. In addition, CD delayed the decline in groundwater level, which allowed the plants to use groundwater at later growth stages, and as a result, the yield and water-use efficiency were improved. CWT1 significantly increased oilseed sunflower yield by 4.52–11.14% and increased water-use efficiency by 1.16–10.8%. Moreover, CWT1 also increased the survival rate of the oilseed sunflower plants by 2.62–2.92%, and the plants demonstrated good growth. Therefore, under CD conditions, plants used soil water and nitrogen more efficiently and, as a result, their productivity was increased, and the water quality was improved.
CAESAR II Tool: Complementary Analyses for Emergency Planning Based on Seismic Risks Impact Evaluations
Authors: Zuccaro Giulio , De Gregorio Daniela , Leone Mattia Federico , Sessa Salvatore , Nardone Stefano , Perelli Francesca Linda
Published: September 2021

Italy is a country with high seismic hazard, however since the delay in the seismic classification of the national territory, most of the existing building heritage does not comply with the current technical standards for buildings. The seismic events that have hit different Italian regions in recent years have highlighted the complexity of the challenge for the public bodies both in the emergency management and post-event reconstruction and in the planning of effective risk prevention and mitigation measures to be implemented in ‘peacetime’. These difficulties concern, in particular, the capacity to properly manage the financial and technical resources available and to identify the intervention priorities throughout the entire emergency cycle. For correct management, the priority is to quantify and localize, through simulations, the quantification of probable damages and to evaluate in terms of cost-benefits the possible alternative strategies for mitigation, also taking into account the potential, in terms of cost-effectiveness, of integrated measures for seismic and energy retrofitting. In this framework, the project CAESAR II (Complementary Analyses for Emergency planning based on Seismic Risks impact evaluations) has been developed as a Decision Support System for Public Authorities in charge of developing Disaster Risk Reduction plans, with the possibility of programming mid to long-term investments for public and private properties, as well as defining custom financial support mechanisms and tax incentives.