bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-Healing Concrete: Concepts, Energy Saving and Sustainability
Authors: Roque Bruno Augusto Cabral , Brasileiro Pedro Pinto Ferreira , Brandão Yana Batista , Casazza Alessandro Alberto , Converti Attilio , Benachour Mohand , Sarubbo Leonie Asfora
Published: February 2023

The production of cement accounts for 5 to 7% of carbon dioxide emissions in the world, and its broad-scale use contributes to climate imbalance. As a solution, biotechnology enables the cultivation of bacteria and fungi for the synthesis of calcium carbonate as one of the main constituents of cement. Through biomineralization, which is the initial driving force for the synthesis of compounds compatible with concrete, and crystallization, these compounds can be delivered to cracks in concrete. Microencapsulation is a method that serves as a clock to determine when crystallization is needed, which is assisted by control factors such as pH and aeration. The present review addresses possibilities of working with bioconcrete, describing the composition of Portland cement, analysis methods, deterioration, as well as environmental and energetic benefits of using such an alternative material. A discussion on carbon credits is also offered. The contents of this paper could strengthen the prospects for the use of self-healing concrete as a way to meet the high demand for concrete, contributing to the building of a sustainable society.
Privacy-Based Demand Response Modeling for Residential Consumers Using Machine Learning with a Cloud–Fog-Based Smart Grid Environment
Authors: Reka S. Sofana , Venugopal Prakash , Ravi V. , Dragicevic Tomislav
Published: February 2023

Demand response modeling in smart grids plays a significant role in analyzing and shaping the load profiles of consumers. This approach is used in order to increase the efficiency of the system and improve the performance of energy management. The use of demand response analysis in determining the load profile enhances the scheduling approach to the user profiles in the residential sector. In accordance with the behavioral pattern of the user’s profile, incentive-based demand response programs can be initiated in the residential sector. In modeling the behavioral pattern of the user’s profile, the machine learning approach is used to analyze the profile patterns. The incentive-based demand response is demonstrated in order to show the importance of maintaining the privacy of residential users, during interactions between demand- and load-profile patterns. In this work, real-time demand response modeling for residential consumers, with incentive schemes, are analyzed. The incentive schemes are proposed in order to show how the privacy of the residential units may be considered, as a result the model is developed with a two-step analysis approach. In the first step, the demand response modeling is performed with the scheduling of appliances on the residential side, by forming hubs in a cloud–fog-based smart grid environment. This process, with an incentive demand response scheme and scheduling of appliances, is performed using an optimal demand response strategy that uses a discounted stochastic game. In the second step, the privacy concerns of the demand response model from the strategy analysis are addressed using a generative adversarial network (GAN) Q-learning model and a cloud computing environment. In this work, the DR strategy model with privacy concerns for residential consumers, along with EV management, is performed in a two-step process and arrives at an optimal strategy. The efficiency and real time analysis proposed in this model are validated with real-time data analysis in simulation studies and with mathematical analysis of the proposed model.
Reliability Testing of Wind Farm Devices Based on the Mean Time between Failures (MTBF)
Authors: Duer Stanisław , Woźniak Marek , Paś Jacek , Zajkowski Konrad , Bernatowicz Dariusz , Ostrowski Arkadiusz , Budniak Zbigniew
Published: February 2023

Among the most valuable types of renewable energy available today is wind energy. The reliability of WF systems must be regularly evaluated at every stage of their “life,” from design to operation, if a wind farm energy system is to be effective and function damage-free. Three key goals are presented in the article. The theory of fundamental quantities in reliability and maintenance analysis should be derived and explained first. Second, as a consequence of maintainability, theoretical correlations between reliability and mean time between failures (MTBF) are provided. The three-state theory of the WF procedure for operation presented in the research serves as the foundation for the analytical analysis of WF reliability. The time between failures is investigated as a function of maintainability, and the dependability of the WF under examination is assessed as a function of service life. The WF owner can make the best decisions to renew the WF and increase its reliability, energy, financial efficiency, etc. by being aware of the existing reliability of the WF system in use.
On the Feasibility of Market Manipulation and Energy Storage Arbitrage via Load-Altering Attacks
Authors: Ospina Juan , Fobes David M. , Bent Russell
Published: February 2023

Around the globe, electric power networks are transforming into complex cyber–physical energy systems (CPES) due to the accelerating integration of both information and communication technologies (ICT) and distributed energy resources. While this integration improves power grid operations, the growing number of Internet-of-Things (IoT) controllers and high-wattage appliances being connected to the electric grid is creating new attack vectors, largely inherited from the IoT ecosystem, that could lead to disruptions and potentially energy market manipulation via coordinated load-altering attacks (LAAs). In this article, we explore the feasibility and effects of a realistic LAA targeted at IoT high-wattage loads connected at the distribution system level, designed to manipulate local energy markets and perform energy storage (ES) arbitrage. Realistic integrated transmission and distribution (T&D) systems are used to demonstrate the effects that LAAs have on locational marginal prices at the transmission level and in distribution systems adjacent to the targeted network.
Evaluating Environmental and Energy Performance Indicators of Food Systems, within Circular Economy and “Farm to Fork” Frameworks
Authors: Ghisellini Patrizia , Ncube Amos , Rotolo Gloria , Vassillo Chiara , Kaiser Serena , Passaro Renato , Ulgiati Sergio
Published: February 2023

This study proposes a framework of environmental and energy performance indicators identified and critically evaluated within the scientific literature and the Agricultural European Database for the monitoring and evaluation of the Common Agricultural Policy of the European Union. The identified set of performance indicators encompasses the whole life cycle of agri-food systems from primary production stage until end-of-life stage in agreement with the circular economy and EU “farm to fork strategy” frameworks. In particular, the practices/goals/targets suggested in the latter (e.g., organic farming goals, more relevance assigned to plant-based diets, support for the creation of short supply chains, and reduction in food losses and waste) have guided the search for the main topics of interest in our analysis and the associated environmental and energy indicators. The results of this study evidence a proposed set of performance indicators selected from the literature among LCA and non-LCA indicators (midpoint LCA impacts, cumulative energy use, emergy accounting, and material flow accounting, among others) that could be helpful in integrating the EU CAP indicators for monitoring and evaluating efforts and achieved results toward implementing and controlling the effectiveness of the adopted “farm to fork” policy and related legislative measures, as well as the application of the circular economy model.
Study of Chelating Agent—Surfactant Interactions on the Interphase as Possibly Useful for the Well Stimulation
Authors: Yunusov Timur Ildarovich , Davletshina Lyutsia Faritovna , Magadova Lyubov Abdulaevna , Silin Mikhail Alexandrovich
Published: February 2023

Chelating agents’ application for EOR and well stimulation is fast growing nowadays. However, reagents of this class have some drawbacks, with high values of interfacial tension (IFT) being among them. IFT may be lowered with the addition of surfactants; however, the simultaneous application of chelating agents and surfactants has not yet been widely studied. This paper focuses on the experimental and theoretical investigation of the interaction between chelating agent (ethylenediaminetetraacetic acid, EDTA) and surfactants of anionic and cationic types (sodium dodecyl sulfate, SDS, and dodecyl trimethynlammonium bromide, DTAB). IFT measurement was performed at ambient conditions, with normal octane being as the reference hydrocarbon to eliminate the temperature and salinity effects and compare surfactant-containing systems. The experimental results show that chelating agents’ addition to the solutions of surfactants leads to a decrease in IFT value. Moreover, surfactants’ critical micelle concentration is lowered, whereas their effectiveness and efficiency are increased, which points to the salting-out nature of chelating agents. Molecular dynamics reveal that chelating agent addition causes closer packing of surfactant layer, the decrease in head groups’ hydration, and, at least in the case of SDS, specific surfactant–chelating agent attractive interaction. These molecular-level insights, experimental dependencies, and the combined methodology may be useful for the proper selection of fluids for real-field operations.
Optimal Management of Battery and Fuel Cell-Based Decentralized Generation in DC Shipboard Microgrids
Authors: Luna Massimiliano , La Tona Giuseppe , Accetta Angelo , Pucci Marcello , Pietra Andrea , Di Piazza Maria Carmela
Published: February 2023

This paper proposes an energy management system (EMS) that aims at managing the modular direct current (DC) microgrids (MGs) of a hybrid DC/AC power system onboard cruise ships. Each shipboard microgrid is an electrically self-sufficient system supplied only by a fuel cell (FC) and a Lithium battery, and it powers the ship’s hotel services. However, continuously varying power demand profiles negatively affect the FC. Thus, the proposed EMS aims to minimize the FC operating point excursion on the source’s characteristic. This goal is pursued by exploiting the battery capability to manage load fluctuations and compensate for power demand forecasting errors. Furthermore, it is accomplished while satisfying all the operational constraints of the shipboard microgrids and ensuring daily battery charging/discharging cycles. The proposed EMS is based on two subsystems: (1) a rule-based microgrid supervisor, which makes the EMS capable of managing black start, normal operating conditions, and transient or faulty conditions; (2) an energy management (EM) algorithm, which allows achieving the desired goal without oversizing the battery, thus granting the cost-effectiveness of the solution and a reduced impact on technical volumes/weights on board. The EMS was tested with specific reference to a real-world case study, i.e., a 48,000 gross tonnage cruise ship under different operating scenarios, including black start and multi-day period operation of shipboard MGs. Test results showed that the operating points of the FC were always in the neighborhood of the point chosen by the MG designer, that the voltage variations were always well below 5%, guaranteeing stable operation, and that the black start operation was suitably handled by the EMS. According to the obtained results, the effectiveness of the proposed approach was assessed.
Combined Application of Organic and Inorganic Fertilizers Effects on the Global Warming Potential and Greenhouse Gas Emission in Apple Orchard in Loess Plateau Region of China
Authors: Sompouviset Thongsouk , Ma Yanting , Zhao Zhiyuan , Zhen Zhaoxia , Zheng Wei , Li Ziyan , Zhai Bingnian
Published: February 2023

Inorganic fertilizers have been widely used to achieve high apple yields throughout China, especially in Northwest China. This approach has adverse effects on apple orchard soil environments and greenhouse gas (GHG) emissions. Therefore, we investigated the effects of combined organic and inorganic fertilizers on GHG emissions, soil properties, and apple yield to assess the greenhouse gas inventory and to determine which fertilization manner is good for the sustainable development of apple orchards. A split plot design was used, with main treatment of fertilizer ditch (FD) site and a bare soil (BS) site, each with four subtreatments: organic fertilizer–goat manure (M), chemical fertilizer (NPK), chemical fertilizer combined with organic fertilizer–goat manure (MNPK), and control (CK). The cumulative N2O emissions at the FD site were higher than those at the BS site (by 105.72%). The N2O emissions ranged from approximately 0.95–5.91 kg ha−1 and were higher in the MNPK treatment than in the other treatments. The cumulative CH4 uptake from each treatment was generally negative (1.06–7.67 kg ha−1). Compared to the other treatments, the MNPK treatment applied at the FD site led to an increased global warming potential. At both the FD and BS sites, the MNPK treatment led to a lower greenhouse gas intensity than the NPK treatment. Nitrates nitrogen (NO3−-N), water-filled pore space, and temperature all influenced GHG emissions. These results showed that the MNPK treatment was more conducive than the other treatments to the sustainable development of apple orchards in the Loess Plateau region of China.
Can River Chief System Policy Improve Enterprises’ Energy Efficiency? Evidence from China
Authors: Gao Da , Liu Chang , Wei Xinyan , Liu Yang
Published: February 2023

The river chief system (RCS) is an autonomous environmental policy implemented by local governments in China that incorporates environmental responsibilities into the performance evaluation. Although existing literature suggests that RCS can reduce water pollution, the impact of RCS on energy efficiency has not been assessed. Therefore, this paper compiles data on industrial enterprises and industrial pollution in China from 2003 to 2013 and empirically examines the impact of RCS on green total factor energy efficiency (GTFEE) by using a multiple difference-in-difference approach. The results show that RCS significantly enhances firms’ GTFEE, and a series of tests confirm the robustness of the findings. Second, we further explore how RCS affects GTFEE, the mechanism tests conclude that the RCS improves GTFEE mainly through optimizing energy structure and promoting technological innovation. Third, compared with small firms, exporters, and firms in non-heavy polluting industries, the RCS has a greater effect on improving the GTFEE of large firms, non-exporters, and firms in heavily polluting industries. This study provides new and novel ideas for emerging countries to improve environmental policies and achieve sustainable development.
Assessing the Contribution of Managerial Accounting in Sustainable Organizational Development in the Healthcare Industry
Authors: Vărzaru Anca Antoaneta , Bocean Claudiu George , Criveanu Maria Magdalena , Budică-Iacob Adrian-Florin , Popescu Daniela Victoria
Published: February 2023

Sustainability and digital transformation are two phenomena influencing the activities of all organizations. Managerial accounting is an essential component of these transformations, having complex roles in decision-making to ensure sustainable development through implementing modern technologies in the accounting process. This paper studies the roles of digitized managerial accounting in organizational sustainability drivers from a decision-making perspective. The empirical investigation assesses the influence of managerial accounting on the economic, social, and environmental drivers of sustainability from the perception of 396 Romanian accountants using an artificial neural network analysis and structural equation modeling. As a result, the research provides a holistic view of the managerial accounting roles enhanced by digital technologies in the sustainable development of healthcare organizations. From the accountants’ perception, the leading managerial accounting roles on organizational sustainability are enablers and reporters of the sustainable value created in the organization. Additionally, the roles of creators and preservers are seen as relevant by a significant part of the respondents. Therefore, healthcare organizations must implement a sustainability vision in managerial accounting and accounting information systems using the capabilities offered by new digital technologies.
Effects of Aging on Adsorption of Tetracycline Hydrochloride by Humin
Authors: Hou Hongbo , Xu Guoliang , He Fei , Pan Hua
Published: February 2023

To explore the effects of “aging”, an environmental factor, on adsorption of tetracycline hydrochloride (TC) by humin (HM), this paper coats HM surface with ferric hydroxide precipitate to simulate the aging process. The research findings indicate that compared with fresh HM, aged HM (HM-Fe) displays an accelerated adsorption rate and higher adsorption capacity on TC. With an initial concentration of 20 mg·L−1, TC’s equilibrium adsorption capacity on HM and HM-Fe is 4.6 and 5.3 mg·g−1, respectively, whereas the corresponding initial adsorption rate is 0.036 and 0.132 mg·g−1·min−1. The pseudo-second-order kinetic model and Freundlich adsorption isotherm model could adequately simulate the adsorption process of TC by HM and HM-Fe, suggesting the occurrence of chemical adsorption and multimolecular layer adsorption between TC and HM and HM-Fe. Based on ΔAbs deduced from Job’s calculation, it can be assumed a complex reaction occurs between the iron element on the HM-Fe surface and TC, which acts as a sort of bridge in strengthening the adsorption of TC by HM-Fe. The aforesaid findings may provide subsequent further study on environmental behaviors of TC in the soil with both fundamental theories and a scientific basis.
The PreserFlo MicroShunt in the Context of Minimally Invasive Glaucoma Surgery: A Narrative Review
Authors: Saeed Emil , Gołaszewska Kinga , Dmuchowska Diana Anna , Zalewska Renata , Konopińska Joanna
Published: February 2023

Recently, the quest for novel glaucoma surgical techniques and devices has been underway. Trabeculectomy remains the gold standard, but it requires the implantation of glaucoma drainage devices and frequent follow-ups, and it also carries a high risk of serious complications. The need for less invasive and safer procedures has led to the development of minimally invasive glaucoma surgery (MIGS), particularly for patients with mild–to–moderate disease. Among them, minimally invasive bleb surgery seems to be effective in classical glaucoma surgery, while maintaining MIGS benefits. The relatively new PreserFlo® MicroShunt (Santen, Osaka, Japan) is registered in Europe. It was released in 2019 for the treatment of patients with early–to–advanced open-angle glaucoma, where intraocular pressure (IOP) remains uncontrolled while on maximum tolerated medication and/or where glaucoma progression warrants surgery. This review focuses on the place of the PreserFlo MicroShunt, characterized by ab externo implantation, among MIGS procedures, discussing its advantages and disadvantages. The mechanisms of action, technical aspects, efficacy, and safety issues are summarized. The surgical technique, its efficacy, and safety profile are described, and directions for future studies are indicated. The PreserFlo MicroShunt ensures a high safety profile, minimal anatomical disruption, meaningful IOP-lowering effect, and ease of use for patients and physicians.
Association between Alcohol Consumption and Body Composition in Russian Adults and Patients Treated for Alcohol-Related Disorders: The Know Your Heart Cross-Sectional Study
Authors: Mitkin Nikita A. , Unguryanu Tatiana N. , Malyutina Sofia , Kudryavtsev Alexander V.
Published: February 2023

There is conflicting evidence about the association between alcohol consumption and body composition (BC). We aimed to investigate this association in Russian adults. The study population included 2357 residents of Arkhangelsk aged 35–69 years, and 272 in-patients treated for alcohol problems (narcological patients) who participated in the Know Your Heart (KYH) cross-sectional study in 2015–2017. The participants were divided into five subgroups based on their alcohol use characteristics: non-drinkers, non-problem drinkers, hazardous drinkers, harmful drinkers, and narcological patients. Considering men, hazardous drinkers had a larger waist circumference (WC), waist-to-hip ratio (WHR), and percentage of body fat mass (%FM) compared to non-problem drinkers. In harmful drinking men, these differences were the opposite: a lower body mass index (BMI), hip circumference (HC), and %FM. Men among narcological patients had the lowest mean BMI, WC, HC, WHR, and %FM compared to other subgroups of men. As for women, non-drinkers had a lower BMI, WC, HC, and %FM compared to non-problem drinkers. Women among narcological patients had the lowest mean BMI and HC but an increased WHR compared to other subgroups of women. In conclusion, alcohol consumption levels had an inverted J-shaped association with adiposity-related BC parameters: they were elevated in hazardous drinkers but were reduced in harmful drinkers, and were even lower in patients with alcohol-related diagnoses.
How Much Is Winning a Matter of Luck? A Comparison of 3 × 3 and 5v5 Basketball
Authors: Csurilla Gergely , Boros Zoltán , Fűrész Diána Ivett , Gyimesi András , Raab Markus , Sterbenz Tamás
Published: February 2023

Background: The comparison of team sports based on luck has a long tradition and remains unsolved. A contrast between the new Olympic format three-on-three (3 × 3) and five-on-five (5v5) forms of basketball has never been analyzed and provides a comparison within the same form of sports. Methods: We developed a new method to calculate performance indicators for each team and invented the Relative Score Difference Index, a new competitive balance indicator that allows the comparison of luck in the two basketball forms for both men and women. We collected game-level data about 3 × 3 and 5v5 from the World Cups held between 2010 and 2019 (N = 666). Luck was defined as the difference between the expected and the actual outcomes of games. Using the basketball World Cup data, we applied the Surprise Index, ran probit regression models, and compared the basketball forms on the goodness-of-fit of the models. Results: As we predicted, there are differential effects of luck between game formats and sex, such that the 3 × 3 form depends more on luck and women’s games are less influenced by luck when compared to men’s games. Conclusion: Coaches may better understand the differences between the two forms and sexes regarding luck if they are aware that the 3 × 3 and men’s competitions are usually more influenced by luck. The findings provide a leverage point for testing new performances and competition balance indicators and will acknowledge the number of games we enjoy watching.
Superheroes or Super Spreaders? The Impact of the COVID-19 Pandemic on Social Attitudes towards Nurses: A Qualitative Study from Poland
Authors: Wałowska Katarzyna , Domaradzki Jan
Published: February 2023

The social perception of the nursing profession in Poland is profoundly affected by social stereotypes that may discourage young people from entering the profession and lead to prejudice towards nurses. During the COVID-19 pandemic, nurses gained visibility, which caused the social image of nurses to likewise grow. In this study, we explore nurses’ experiences with respect to how the COVID-19 pandemic influenced the social image of nursing. Semi-structured interviews were conducted with fifteen hospital nurses. Three major themes emerged: (1) social attitudes towards nurses during the pandemic, (2) nurses’ perception of the impact of the pandemic on the social image of the nursing profession and (3) the impact of the pandemic on nurses’ mental health. Although the pandemic promoted the image of nursing to the general public, nurses were disappointed that in the face of the healthcare crisis and the constant threat, they had to struggle with difficult working conditions and professional, social and economic recognition. This study therefore stresses the duty of policy makers to undertake a systemic approach to improving the organisation of health care and increase nurses’ safety by providing them with a safe working environment and prepare them better for the next health crisis.
Affective Out-World Experience via Virtual Reality for Older Adults Living with Mild Cognitive Impairments or Mild Dementia
Authors: Matsangidou Maria , Solomou Theodoros , Frangoudes Fotos , Ioannou Konstantinos , Theofanous Panagiotis , Papayianni Ersi , Pattichis Constantinos S.
Published: February 2023

Older adults with cognitive impairments may face barriers to accessing experiences beyond their physical premises. Previous research has suggested that missing out on emotional experiences may affect mental health and impact cognitive abilities. In recent years, there has been growing research interest in designing non-pharmacological interventions to improve the health-related quality of life of older adults. With virtual reality offering endless opportunities for health support, we must consider how virtual reality can be sensitively designed to provide comfortable, enriching out-world experiences to older adults to enhance their emotional regulation. Thirty older adults living with mild cognitive impairment or mild dementia participated in the study. Affect and emotional behavior were measured. The usability and the sense of presence were also assessed. Finally, we assessed the virtual reality experiences based on physiological responses and eye-tracking data. The results indicated that virtual reality can positively enhance the mental health of this population by eliciting a positive affective state and enhancing their emotional regulation. Overall, this paper raises awareness of the role of virtual reality in emotion elicitation, regulation, and expression and enhances our understanding of the use of virtual reality by older adults living with mild cognitive impairments or mild dementia.
Nasopharyngeal Carcinoma Burden and Its Attributable Risk Factors in China: Estimates and Forecasts from 1990 to 2050
Authors: Zhang Ruhao , He Yifei , Wei Bincai , Lu Yongbo , Zhang Jingya , Zhang Ning , He Rongxin , Xue Hao , Zhu Bin
Published: February 2023

Nasopharyngeal carcinoma (NPC) is an uncommon and aggressive malignant head and neck cancer, which is highly prevalent in southern and southwestern provinces in China. The aim of this study was to examine the disease burden and risk factors of nasopharyngeal carcinoma in China from 1990 to 2019 and to predict the incidence trends from 2020 to 2049. All data were extracted from the 2019 Global Burden of Disease (GBD) study. Joinpoint regression and age-period-cohort (APC) models were chosen to analyze prevalence trends. The temporal trends and age distribution of risk factors were also analyzed descriptively. Bayesian APC models were used to predict the prevalence from 2020 to 2049. The results indicate a higher disease burden in men and older adults. Their attributable risk factors are smoking, occupational exposure to formaldehyde, and alcohol use. We predict that the incidence will be on the rise in all age groups between 2020 and 2049, with the highest incidence in people aged 70 to 89 years. In 2049, the incidence rate is expected to reach 13.39 per 100,000 (50–54 years), 16.43 (55–59 years), 17.26 (60–64 years), 18.02 (65–69 years), 18.55 (70–74 years), 18.39 (75–79 years), 19.95 (80–84 years), 23.07 (85–89 years), 13.70 (90–94 years), and 6.68 (95+ years). The findings of this study might deserve consideration in China’s NPC prevention and control policy design.
An Intensive Longitudinal Assessment Approach to Surveilling Trajectories of Burnout over the First Year of the COVID Pandemic
Authors: Pan Cynthia X. , Crupi Robert , August Phyllis , Sundaram Varuna , Norful Allison A. , Schwartz Joseph E. , Miele Andrew S. , Simons R. Rhiannon , Mikrut Emilia E. , Brondolo Elizabeth
Published: February 2023

Frontline clinicians responding to the COVID-19 pandemic are at increased risk of burnout, but less is known about the trajectory of clinician burnout as caseloads increase and decrease. Personal and professional resources, including self-efficacy and hospital support, can attenuate the risk of burnout. Yet, empirical data documenting how burnout and resources changed as the pandemic waxed and waned are limited. This intensive longitudinal prospective study employed ecological momentary assessment methods to examine trajectories of burnout and resources over the pandemic’s first year in a New York City hospital. A 10-item survey was emailed every 5 days to frontline clinicians (physicians, nurses, and physician assistants). The primary outcome was a single-item validated measure of burnout; predictors included daily hospital COVID-19-related caseloads and personal and professional resources. Clinicians (n = 398) completed the initial survey and an average of 12 surveys over the year. Initially, 45.3% of staff reported burnout; over the year, 58.7% reported burnout. Following the initial COVID peak, caseloads declined, and burnout levels declined. During the second wave of COVID, as caseloads increased and remained elevated and personal and professional resource levels decreased, burnout increased. This novel application of intensive longitudinal assessment enabled ongoing surveillance of burnout and permitted us to evaluate how fluctuations in caseload intensity and personal and professional resources related to burnout over time. The surveillance data support the need for intensified resource allocation during prolonged pandemics.
Central Sensitization and Chronic Pain Personality Profile: Is There New Evidence? A Case-Control Study
Authors: Lopez-Ruiz Marina , Doreste Soler Andrea , Pujol Jesus , Losilla Josep-Maria , Ojeda Fabiola , Blanco-Hinojo Laura , Martínez-Vilavella Gerard , Gutiérrez-Rosado Teresa , Monfort Jordi , Deus Joan
Published: February 2023

Background: Personality traits are relevant for pain perception in persistent pain disorders, although they have not been studied in depth in sensitized and nonsensitized patients with knee osteoarthritis (OA). Objective: To explain and compare the personality profile of patients with OA, with and without central sensitization (CS), and fibromyalgia (FM). Setting: Participants were selected at the Rheumatology Department in two major hospitals in Spain. Participants: Case-control study where the sample consists of 15 patients with OA and CS (OA-CS), 31 OA without CS (OA-noCS), 47 FM, and 22 controls. We used a rigorous and systematic process that ensured the sample strictly fulfilled all the inclusion/exclusion criteria, so the sample is very well delimited. Primary outcome measures: Personality was assessed by the Temperament and Character Inventory of Cloninger. Results: The percentile in harm-avoidance dimension for the FM group is higher compared to OA groups and controls. The most frequent temperamental profiles in patients are cautious, methodical, and explosive. Patients with FM are more likely to report larger scores in harm-avoidance, with an increase in logistic regression adjusted odds ratio (ORadj) between 4.2% and 70.2%. Conclusions: Harm-avoidance seems to be the most important dimension in personality patients with chronic pain, as previously found. We found no differences between OA groups and between sensitized groups, but there are differences between FM and OA-noCS, so harm-avoidance might be the key to describe personality in patients with CS rather than the presence of prolonged pain, as found in the literature before.
Communities Setting the Direction for Their Right to Nutritious, Affordable Food: Co-Design of the Remote Food Security Project in Australian Indigenous Communities
Authors: Ferguson Megan , Tonkin Emma , Brimblecombe Julie , Lee Amanda , Fredericks Bronwyn , Cullerton Katherine , Mah Catherine L. , Brown Clare , McMahon Emma , Chatfield Mark D. , Miles Eddie , Cadet-James Yvonne
Published: February 2023

Despite long histories of traditional food security, Indigenous peoples globally are disproportionately exposed to food insecurity. Addressing this imbalance must be a partnership led by Indigenous peoples in accordance with the UN Declaration of the Rights of Indigenous Peoples. We report the co-design process and resulting design of a food security research project in remote Australia and examine how the co-design process considered Indigenous peoples’ ways of knowing, being, and doing using the CREATE Tool. Informed by the Research for Impact Tool, together Aboriginal Community Controlled Health Organisation staff, Indigenous and non-Indigenous public health researchers designed the project from 2018–2019, over a series of workshops and through the establishment of research advisory groups. The resulting Remote Food Security Project includes two phases. Phase 1 determines the impact of a healthy food price discount strategy on the diet quality of women and children, and the experience of food (in)security in remote communities in Australia. In Phase 2, community members propose solutions to improve food security and develop a translation plan. Examination with the CREATE Tool showed that employing a co-design process guided by a best practice tool has resulted in a research design that responds to calls for food security in remote Indigenous communities in Australia. The design takes a strengths-based approach consistent with a human rights, social justice, and broader empowerment agenda. Trial registration: The trial included in Phase 1 of this project has been registered with Australian New Zealand Clinical Trials Registry: ACTRN12621000640808.
Linking Urban Planning, Community Environment, and Physical Activity: A Socio-Ecological Approach
Authors: Zhang Xue , Warner Mildred E.
Published: February 2023

Lack of physical activity is a growing concern among public health advocates and urban planners. Our socio-ecological model incorporates urban planning and World Health Organization actions on physical activity to identify key factors related to leisure-time physical activity at the community level. Our 2019 nationwide US survey of 1312 communities enables examination of the influence of individual, community, and policy levels on physical activity. Individual factors—poverty, aging, minority population, and longer commuting time—result in lower physical activity. Community-level factors have both positive and negative effects. Physical activity is lower in rural and suburban communities, but higher in communities with more transportation services, recreation and social activities, and safety. Communities with mixed-use neighborhoods and complete streets also show higher levels of physical activity. At the policy level, zoning and cross-agency collaboration have an indirect effect on physical activity by increasing these community-level factors. This suggests an alternative approach to promoting physical activity. Local governments can promote transportation, recreation and safety, especially in rural and minority communities lacking active-friendly built environments and facing challenges from aging population, poverty, and longer commuting time. This socio-ecological approach can assess multilevel factors related to physical activity in other countries.
The Impact of Household Debt on the Health of the Elderly in China: Evidence from China Family Panel Studies
Authors: Liu Ziyu , Zhao Ke , Liu Jinquan , Liu Yongfu
Published: February 2023

With the aging of China’s population and the expansion of household debt, the health of the elderly has become an important social issue. Based on the 2018 China Family Panel Studies (CFPS) database, we explored the impact of household debt on the health of older adults and the mechanism of transmission. The Oprobit and IV-Oprobit models were employed for our analysis. Results: (1) Household debt had a significant negative impact on both the physical and mental health of older adults. (2) Female older adults were more sensitive to the impact of household debt. Additionally, a higher education level led to an increasing impact of debt on mental health, but physical health was only affected in the low-education group. (3) The impact of household debt had an inverted U-shape relationship with household income, indicating that, as household income increases, the impact on health level first rises and then reduces after peaking at a middling level of income. (4) According to the mechanism analysis, household debt affects the health of the elderly by causing them to return to work and reducing their medical expenditures. Considering the above conclusions, we put forward some policy implications to alleviate the health problems of the elderly.
Investigation of the Exposure of Schoolchildren to Ultrafine Particles (PM0.1) during the COVID-19 Pandemic in a Medium-Sized City in Indonesia
Authors: Handika Rizki Andre , Phairuang Worradorn , Amin Muhammad , Yudison Adyati Pradini , Anggraini Febri Juita , Hata Mitsuhiko , Furuuchi Masami
Published: February 2023

The health risk of schoolchildren who were exposed to airborne fine and ultrafine particles (PM0.1) during the COVID-19 pandemic in the Jambi City (a medium-sized city in Sumatra Island), Indonesia was examined. A questionnaire survey was used to collect information on schoolchildren from selected schools and involved information on personal profiles; living conditions; daily activities and health status. Size-segregated ambient particulate matter (PM) in school environments was collected over a period of 24 h on weekdays and the weekend. The personal exposure of PM of eight selected schoolchildren from five schools was evaluated for a 12-h period during the daytime using a personal air sampler for PM0.1 particles. The schoolchildren spent their time mostly indoors (~88%), while the remaining ~12% was spent in traveling and outdoor activities. The average exposure level was 1.5~7.6 times higher than the outdoor level and it was particularly high for the PM0.1 fraction (4.8~7.6 times). Cooking was shown to be a key parameter that explains such a large increase in the exposure level. The PM0.1 had the largest total respiratory deposition doses (RDDs), particularly during light exercise. The high level of PM0.1 exposure by indoor sources potentially associated with health risks was shown to be important.
Family Characteristics, Transgender Identity and Emotional Symptoms in Adolescence: A Population Survey Study
Authors: Kaltiala Riittakerttu , Heino Elias , Marttunen Mauri , Fröjd Sari
Published: February 2023

Sociodemographic and psychosocial family factors have profound implications for adolescent development, identity formation and mental health during the adolescent years. We explored the associations of sociodemographic and psychosocial family factors with transgender identity in adolescence and the role of these factors in the associations between gender identity and emotional disorders. Data from a large adolescent population survey from Finland were analysed using logistic regression models. Reporting transgender identity was associated with mother’s low level of education, accumulating family life events, lack of family cohesion, perceived lack of family economic resources and female sex. A lack of family cohesion further differentiated between adolescents reporting identifying with the opposite sex and those reporting non-binary/other gender identification. The associations between transgender identity, depression and anxiety were attenuated but did not level out when family factors were controlled for. Transgender identity in adolescence is associated with socioeconomic and psychosocial family factors that are known correlates of negative outcomes in mental health and psychosocial well-being. However, transgender identification is also associated with emotional disorders independent of these family factors.
Coaching Robots for Older Seniors: Do They Get What They Expect? Insights from an Austrian Study
Authors: Schneider Cornelia , Bousbiat Hafsa
Published: February 2023

To support the increasing number of older people, new (assistive) technologies are constantly being developed. For these technologies to be used successfully, future users need to be trained. Due to demographic change, this will become difficult in the future, as the resources for training will no longer be available. In this respect, coaching robots could have great potential to support younger seniors in particular. However, there is little evidence in the literature about the perceptions and potential impact of this technology on the well-being of older people. This paper provides insights into the use of a robot coach (robo-coach) to train younger seniors in the use of a new technology. The study was carried out in Austria in autumn 2020, involving 34 participants equally distributed among employees in their last three years of service and retirees in their first three years of retirement (23 female; 11 male). The aim was to assess participants’ expectations and perceptions by examining the perceived ease of use and user experience of the robot in providing assistance during a learning session. The findings reveal a positive impression of the participants and promising results for using the robot as a coaching assistant in daily tasks.
Spatial Association Network Evolution and Variance Decomposition of Economic Sustainability Development Efficiency in China
Authors: Fang Xin , Cao Yun
Published: February 2023

The economy’s sustainable development has become a national strategic deployment in China. Research on the difference between the economic sustainable development efficiency (ESDE) and the spatial network will assist the government with the deployment of sustainable development strategies and the achievement of the “peak carbon dioxide emissions”. This paper designs the input–output indicator system of sustainable economic development efficiency and builds an unexpected output super-EBM-Malmquist model to measure the ESDE of 30 provinces in China from 2008–2020. According to the ranking of ESDE, the 30 provinces in China are classified into four groups by applying the quartile method, and the difference in the ESDE in different regions and the temporal variation of different provinces are studied by using the Dagum Gini coefficient and Gaussian Kernel density. Moreover, the relationship between ESDE in different provinces is studied based on the revised gravity model and social network analysis method. The connections between provinces with related relations constitute the ESDE network. Results show that (1) the average ESDE in China shows an upward trend, the eastern region is in a leading position, the central and western regions are trying to catch up with the eastern region, and the development of the northeast region is lagging behind. (2) The level of ESDE in different provinces is clearly arranged from high to low, illuminating a distinct pattern. Moreover, provinces with high levels of development are much higher than provinces with low levels of development, presenting a phenomenon of polarization. (3) The regional ESDE development imbalance is prominent, and the ESDE in the eastern region is closely related, while the connection in the western region is lower. (4) Beijing–Tianjin Urban Agglomeration and the Yangtze River Delta have significant spatial spillover effects in the association network, while the northeast, northwest, southwest and central regions have significant spatial benefit relationships. These findings provide important enlightenment for promoting the sustainable and balanced development of China’s economy.
Correction: Cipolletta et al. Risk Perception towards COVID-19: A Systematic Review and Qualitative Synthesis. Int. J. Environ. Res. Public Health 2022, 19, 4649
Authors: Cipolletta Sabrina , Andreghetti Gabriela Rios , Mioni Giovanna
Published: February 2023

In the original publication [...]
Specific Activation of Yamanaka Factors via HSF1 Signaling in the Early Stage of Zebrafish Optic Nerve Regeneration
Authors: Sugitani Kayo , Mokuya Takumi , Homma Shuichi , Maeda Minami , Konno Ayano , Ogai Kazuhiro
Published: February 2023

In contrast to the case in mammals, the fish optic nerve can spontaneously regenerate and visual function can be fully restored 3–4 months after optic nerve injury (ONI). However, the regenerative mechanism behind this has remained unknown. This long process is reminiscent of the normal development of the visual system from immature neural cells to mature neurons. Here, we focused on the expression of three Yamanaka factors (Oct4, Sox2, and Klf4: OSK), which are well-known inducers of induced pluripotent stem (iPS) cells in the zebrafish retina after ONI. mRNA expression of OSK was rapidly induced in the retinal ganglion cells (RGCs) 1–3 h after ONI. Heat shock factor 1 (HSF1) mRNA was most rapidly induced in the RGCs at 0.5 h. The activation of OSK mRNA was completely suppressed by the intraocular injection of HSF1 morpholino prior to ONI. Furthermore, the chromatin immunoprecipitation assay showed the enrichment of OSK genomic DNA bound to HSF1. The present study clearly showed that the rapid activation of Yamanaka factors in the zebrafish retina was regulated by HSF1, and this sequential activation of HSF1 and OSK might provide a key to unlocking the regenerative mechanism of injured RGCs in fish.
The Molecular Heterogeneity of Store-Operated Ca2+ Entry in Vascular Endothelial Cells: The Different roles of Orai1 and TRPC1/TRPC4 Channels in the Transition from Ca2+-Selective to Non-Selective Cation Currents
Authors: Moccia Francesco , Brunetti Valentina , Perna Angelica , Guerra Germano , Soda Teresa , Berra-Romani Roberto
Published: February 2023

Store-operated Ca2+ entry (SOCE) is activated in response to the inositol-1,4,5-trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store and represents a ubiquitous mode of Ca2+ influx. In vascular endothelial cells, SOCE regulates a plethora of functions that maintain cardiovascular homeostasis, such as angiogenesis, vascular tone, vascular permeability, platelet aggregation, and monocyte adhesion. The molecular mechanisms responsible for SOCE activation in vascular endothelial cells have engendered a long-lasting controversy. Traditionally, it has been assumed that the endothelial SOCE is mediated by two distinct ion channel signalplexes, i.e., STIM1/Orai1 and STIM1/Transient Receptor Potential Canonical 1(TRPC1)/TRPC4. However, recent evidence has shown that Orai1 can assemble with TRPC1 and TRPC4 to form a non-selective cation channel with intermediate electrophysiological features. Herein, we aim at bringing order to the distinct mechanisms that mediate endothelial SOCE in the vascular tree from multiple species (e.g., human, mouse, rat, and bovine). We propose that three distinct currents can mediate SOCE in vascular endothelial cells: (1) the Ca2+-selective Ca2+-release activated Ca2+ current (ICRAC), which is mediated by STIM1 and Orai1; (2) the store-operated non-selective current (ISOC), which is mediated by STIM1, TRPC1, and TRPC4; and (3) the moderately Ca2+-selective, ICRAC-like current, which is mediated by STIM1, TRPC1, TRPC4, and Orai1.