bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Reductive Generation of Aldehyde Metal Enolate from Ketene. A One‐Flask Process to 1,1,2‐ and 1,2,2‐Trisubstituted Dihydronapthalenes from 1‐and 2‐Naphthalenecarboxylates.
Authors: TOMIOKA K. , SHINDO M. , KOGA K.
Published: May 2016

The naphthalene‐1‐carboxylate (I) reacts with the organolithium compounds (II), forming the ester enolates (III) which are reduced with the borohydride (IV) to give the aldehyde enolates (V).
ChemInform Abstract: Podand‐Catalyzed Nucleophilic Aromatic Substitutions of Anthraquinones: A Novel Synthetic Approach and a Mechanistic Suggestion from Solid‐State Data.
Authors: LU T. , YOO H. K. , ZHANG H. , BOTT S. , ATWOOD J. L. , ECHEGOYEN L. , GOKEL G. W.
Published: May 2016

Reaction of the chloroanthraquinone (I) with the alcohols (II) and sodium hydride is only successful in the presence of calytic amounts of a podand such as triglycol monomethyl ether, yielding the corresponding alkoxyanthraquinones (III).
ChemInform Abstract: N‐Vinyl and N‐Unsubstituted β‐Lactams from 1‐Substituted 2‐Aza‐1,3‐butadienes.
Authors: GEORG G. I. , HE P. , KANT J. , MUDD J.
Published: May 2016

The aldehydes (I) react with 1,1‐dimethylethylenediamine (II) to form the N‐(aminoethyl)imines (III) which are subjected to Hofmann elimination to give the azadienes (IV).
ChemInform Abstract: Phosphorus‐Containing Carboxylic Thioamides in the Synthesis of Heterocyclic Compounds.
Authors: KOZLOV V. A. , ZHELTOVA E. V. , NEGREBETSKII V. V. , GRAPOV A. F. , MEL'NIKOV N. N.
Published: May 2016

The phosphorylated cyanothioacetamides (I) are coupled with the α‐halo ketones (II) to give the ketene S,N‐acetals (III) of which (IIIa), (IIIc), and (IIId) are converted into the thiophenes (Va), (Vc), (Vd), and (IVc) upon thermal treatment.
ChemInform Abstract: Syn‐Anti Isomerism in the 1,3‐Dipolar Cycloaddition to cis‐3,4‐Disubstituted Cyclobutenes. Part 5. Diastereoselectivity in the Reaction with Diazoalkanes.
Authors: BURDISSO M. , GAMBA A. , GANDOLFI R. , TOMA L. , RASTELLI A. , SCHIATTI E.
Published: May 2016

The 1,3‐dipolar cycloaddition of diazomethane (II) to cis‐3,4‐disubstituted cyclobutenes (I) predominantly yields the syn/anti‐cycloadducts (III) and (IV) with a strong preference of the syn‐isomers (III).
ChemInform Abstract: Some Highly Fluorinated Acyclic, Cyclic, and Polycyclic Derivatives of Cl2NCF2CF2NCl2 and Cl2C=NCCl2CCl2N=CCl2.
Authors: SARWAR G. , KIRCHMEIER R. L. , SHREEVE J. M.
Published: May 2016

The perhalogenated ethylenediamine (I) is coupled with the trifluoroethylenes (II) to form the bisadducts (III).
ChemInform Abstract: 5‐Substituted‐3‐phenacyl‐2‐iminooxazolidines as Antiarrhythmic and Local Anaesthetic Agents.
Authors: MISIASZEC C. , JARRY C. , PANCONI E. , CARPY A.
Published: May 2016

A variety of title compounds of type (III) are synthesized.
ChemInform Abstract: Pyridinium Azolate Betaines and Their Derivatives: A New Class of Antiprotozoal Agents.
Authors: ALCALDE E. , DINARES I. , ELGUERO J. , FRIGOLA J. , OSUNA A. , CASTANYS S.
Published: May 2016

Compounds of type (III), (IV) and (VI)‐(IX) show anti‐leishmanial activity in vitro.
ChemInform Abstract: Substituted 1,4‐Dihydro‐1‐phenylisoquinolin‐3(2H)‐ones as Inhibitors of Cyclic Nucleotide Phosphodiesterases from Dog Heart.
Authors: ST. GEORGIEV V. , VAN INWEGEN R. G. , CARLSON P.
Published: May 2016

The title compounds, e.g. (III) and (V), show activity as inhibitors of the title phosphodiesterase.
ChemInform Abstract: Sulfur‐Stabilized Carbanions: Electrophilic Reactions of Allylic Anion Containing Propanedithio and Phenylthio Substituents.
Authors: FANG J.‐M. , CHEN M.‐Y.
Published: May 2016

Treatment of the (phenylthio)ethylidenedithiane (V), prepared from the bromoacrolein (I) via the bromodithiane (IV), with butyllithium and subsequent reaction with the alkyl halides (VI) result in the predominant formation of the ring‐alkylated products (VII).
ChemInform Abstract: A Mild and Regiospecific Synthesis of 3‐Amino Substituted Triazolo‐(4,3‐c)‐pyrimidines by Cyclization of 4‐Hydrazinopyrimidines with Iminium Chlorides and with N‐Aryl Phosgenimines.
Authors: GUILLOT N. , VIEHE H. G. , TINANT B. , DECLERCQ J. P.
Published: May 2016

Cyclization of the hydrazinopyrimidine (I) with a series of phosgeniminium salts such as (II) gives the triazolo(4,3‐c)pyrimidines (III) without isomerization.
ChemInform Abstract: Intramolecular Alkene‐Oxirane Cycloadditions. Synthesis and Structure of 5‐Oxapentacyclo(7.3.0.03,7.04,12.06,10)dodecane‐2,8‐dione.
Authors: MARCHAND A. P. , REDDY G. M. , WATSON W. H. , KASHYAP R.
Published: May 2016

During the recrystallization procedure, the title compound (III) gradually is converted to the corresponding ketone hydrate (IV), the structure of which is established by X‐ray analysis (P1; Z=2).
ChemInform Abstract: Preparation of Triaza, Tetraaza, and Peraza Crown Compounds Containing Aminoalkyl Side Groups or Unsubstituted Ring Nitrogen Atoms.
Authors: KRAKOWIAK K. E. , BRADSHAW J. S. , IZATT R. M.
Published: May 2016

Preparation of functionalized macrocyclic ligands of type (V) is achieved by reaction of substituted diamines, e.g. (I), with chloroacetyl chloride (II).
ChemInform Abstract: Stereochemistry of Aluminum Chloride‐Catalyzed Hydrosilylation of Methylcyclohexenes.
Authors: YAMAMOTO K. , TAKEMAE M.
Published: May 2016

The methylcyclohexenes (I) and dimethylchlorosilane (II) undergo addition reaction in the presence of aluminum trichloride to yield the cis‐methyl(dimethylchlorosilyl)cyclohexanes (III).
ChemInform Abstract: Do Nonclassical Silabenzene Anions Exist? Synthesis and X‐Ray Crystal Structure of Crown Ether Stabilized Lithium Silacyclohexadienides, Li(12‐crown‐4)2Me2SiC5H5 and Li(12‐crown‐4)2‐tBu(H)SiC5H5.
Authors: JUTZI P. , MEYER M. , DIAS H. V. R. , POWER P. P.
Published: May 2016

Metalation of the 1‐silacyclohexadienes (I) with BuLi (II) leads to the corresponding silacyclohexadienyl‐Li compounds which on further treatment with 12‐crown‐4 (III) afford the crystalline title compounds (IV) ((IVa): space group P21/n, Z=4) as solvent‐separated ion pairs with free silacyclohexadienide anions.
ChemInform Abstract: Regio‐ and Stereoselectivity of the Nucleophilic Addition of Thiols to Alkynylphosphonites and ‐phosphines.
Authors: PESHKOV A. F. , TRISHIN YU. G. , CHISTOKLETOV V. N.
Published: May 2016

The alkynylphosphonites (I) or the ethynylphosphine (IV) are coupled with the thiols (II) to give regiospecifically the adducts (III) and (V) with predominance of the Z‐isomers.
ChemInform Abstract: Reaction of 1‐(2,2,3,3‐Tetrafluoropropoxy)‐1,3,2‐benzodioxaphosphole with Tribromoacetaldehyde. Novel Phosphoranes and Their Reactivity.
Authors: OFITSEROV E. N. , MIRONOV V. F. , SINYASHINA T. N. , KONOVALOVA I. V. , PUDOVIK A. N.
Published: May 2016

The pyrocatechol phosphite (I) is coupled with bromal (II) to give the phosphates (IV) and (V) via the phosphorane (III).
ChemInform Abstract: Synthesis and Transformations of 4‐(2‐Furyl)‐3‐cyano‐2(1H)‐pyridineselones.
Authors: DYACHENKO V. D. , TUROV A. V. , SHARANIN YU. A.
Published: May 2016

The furfurylidenemalononitriles (Ia) ‐ (Ic) react with the cyanoselenoacetamide (II) to give the pyridineselones (III) which are alkylated, producing the alkylselenopyridines (V).
ChemInform Abstract: The Metal‐Promoted Hydration of Di‐2‐pyridyl Ketone: UV‐VIS Spectra of Cu(II) and Cr(III) in Aqueous Solution with Di‐2‐pyridyl Ketone and the X‐Ray Structure Analysis of Bis‐2,2′,N,N′‐bipyridyl Ketone Hydrate Chromium(III) Chloride and Ruthenium.
Authors: SOMMERER S. , JENSEN W. P. , JACOBSON R. A.
Published: May 2016

UV/VIS spectra of solutions of Cu(II) and Cr(III) with the title ketone reveal that initial coordination is rapid but that weeks are required to form the complex compounds that crystallize from solution.
ChemInform Abstract: Molybdenum(VI) Alcoholates.
Authors: TUROVA N. YA. , KESSLER V. G.
Published: May 2016

Electrochemical oxidation of molybdenum (I) in the presence of the alcohols (II) gives the oxomolybdenum tetraalkoxides (III).
ChemInform Abstract: Synthesis and Magnetic Properties of Binuclear Iron(III) Complexes with Oxalate, 2,5‐Dihydroxy‐1,4‐benzoquinone Dianion, and Squarate as Bridging Ligands. Crystal Structure of (μ‐1,3‐Squarato)bis((N,N′‐ethylenebis(salicylideneaminato))(methanol)iron(II# I)).
Authors: LLORET F. , JULVE M. , FAUS J. , SOLANS X. , JOURNAUX Y. , MORGENSTERN‐BADARAU I.
Published: May 2016

Similarly to the complex (IV), (space group P21/a, Z=2), two other complexes of this type, bridged by oxalate or the dianion of 2,5‐dihydroxy‐1,4‐benzoquinone, without the coordinated MeOH molecule are prepared.
ChemInform Abstract: Linear Oligophosphaalkanes. Part 23. Novel Copper(I) Complexes with Electron‐Deficient Triply Bridging Secondary Phosphido Groups μ3‐PRR′ (R: iPr, tBu, R′: CH2‐PR2; R = R′: Ph).
Authors: BRAUER D. J. , HESSLER G. , KNUEPPEL P. C. + , STELZER O.
Published: May 2016

The μ3‐phosphido‐bridged Cu(I) compounds (IV), (VIII), and (IX) are obtained according to the scheme.
ChemInform Abstract: Synthesis, Characterization, and EPR Studies of Stable Ruthenium(III) Schiff Base Chloro and Carbonyl Complexes.
Authors: KHAN M. M. T. , SRINIVAS D. , KURESHY R. I. , KHAN N. H.
Published: May 2016

Fourteen stable Ru(III) carbonyl chelate complexes such as (III), (IV) and (V) are prepared from their respective parent chloro compounds as outlined for the example of (III) (yields not given).
ChemInform Abstract: A Direct Total Synthesis of (+)‐Longifolene via an Intramolecular Diels‐Alder Strategy.
Authors: LEI B. , FALLIS A. G.
Published: May 2016

Treatment of the lactone (VI) with BF3‐etherate/MeOH gives a mixture of diene isomers (not specified) which are heated in toluene to give a single adduct (IX).
ChemInform Abstract: Highly Stereoselective Synthesis of Two Natural Olefinic Diols via N‐Oxide (2,3)Sigmatropic Rearrangement.
Authors: SATO K. , INOUE S. , IWASE N. , HONDA K.
Published: May 2016

The (2,3)sigmatropic rearrangement of α‐substituted N,N‐dimethylmethallylamine N‐oxides (cf.
ChemInform Abstract: Total Synthesis of Clavamine, Insecticidally Active Compound Isolated from Venom of Joro Spider (Nephila clavata).
Authors: TESHIMA T. , MATSUMOTO T. , MIYAGAWA M. , WAKAMIYA T. , SHIBA T. , NARAI N. , YOSHIOKA M.
Published: May 2016

The title toxin (I) is totally synthesized in order to confirm the proposed structure.
ChemInform Abstract: Reaction of Some 1,2,4‐Triazines with Acetobromoglucose.
Authors: EID M. M. , ABDEL HADY S. A. , ALI H. A. W.
Published: May 2016

The triazinethione (I) is coupled with the tetraacetylglucosyl bromide (II) to form selectively the N‐β‐glucoside (III).
ChemInform Abstract: Regioselective Introduction of Allylic Groups into the C‐2 or C‐3 Position of Furanoside Rings.
Authors: OHMORI J. , SHIOTANI T. , MITSUNOBU O.
Published: May 2016

The α‐furanoside (I) reacts with the allylic Grignard compounds (II) to form predominantly the 2‐deoxy‐2‐C‐alkenylfuranosides (III).
ChemInform Abstract: Synthesis of the Aspidosperma Skeleton Through Allylsilane N‐Acyliminium Cyclization.
Authors: MITTENDORF J. , HIEMSTRA H. , SPECKAMP W. N.
Published: May 2016

A highly stereoselective synthesis of the Aspidosperma ring system (VII) is described, based on the combination of two stereocontrolled processes.
ChemInform Abstract: Synthesis of Racemic Cryptostylines I, II, and III by Radical Cyclization.
Authors: TAKANO S. , SUZUKI M. , KIJIMA A. , OGASAWARA K.
Published: May 2016

Consecutive reaction of the phenethylamines (I) with the benzaldehydes (II) give the imines (III) which are reductively cyclized with tributylstannane to yield mixtures of the isoquinolines (IV) formed by endo‐cyclization and the benzylindolines (V) formed via exo‐cyclization.
ChemInform Abstract: Vitamin B12, a Catalyst in the Synthesis of Prostaglandins.
Authors: BUSATO S. , TINEMBART O. , ZHANG Z. , SCHEFFOLD R.
Published: May 2016

The intermediates (IV) and (‐)‐(V) in the synthesis of prostaglandins are synthesized via vitamin B12‐catalyzed cyclization/addition and cyclization/elimination sequence, respectively.
ChemInform Abstract: Synthesis and Chemistry of a Quinone Methide Model for Anthracycline Antitumor Antibiotics.
Authors: ANGLE S. R. , YANG W.
Published: May 2016

In order to understand the chemistry of anthracycline antitumor antibiotics, a simple stable o‐quinone methide, i.e. compound (IV), is prepared.
ChemInform Abstract: Total Synthesis of (+)‐Breynolide.
Authors: WILLIAMS D. R. , JASS P. A. , TSE H.‐L. A. , GASTON R. D.
Published: May 2016

Each of the spiro ethers (XIII) and (XIV) can be converted to the natural product via a five‐step sequence.
ChemInform Abstract: A New Synthesis of (+)‐Didemnenones A and B.
Authors: SUGAHARA T. , OHIKE T. , SOEJIMA M. , TAKANO S.
Published: May 2016

A new and practical synthesis of didemnenone A (XII) and B (XIII) (constituents of Trididemnum cf.
ChemInform Abstract: The Crystal Structure of Na2CuFeF7, a New Variant in the Weberite Family.
Authors: YAKUBOVICH O. V. , URUSOV V. S. , FRENZEN G. , MASSA W. , BABEL D.
Published: May 2016

A reinvestigation of the structure of the title compound by single crystal XRD confirms its intermediate position between orthorhombic and trigonal weberites.
ChemInform Abstract: Crystal Structure of CuLaW2O8 and CuSmW2O8.
Authors: BOEHLKE A. , MUELLER‐BUSCHBAUM HK. +
Published: May 2016

The title compounds are prepared by reaction of Cu2WO4, Ln2O3 (Ln: La, Sm), and WO3 (6:1:3) at 950 °C under nitrogen atmosphere.
ChemInform Abstract: 127I NMR Spectra of Transition‐Metal Periodate Complexes.
Authors: EVANS J. , LEVASON W. , SPICER M. D.
Published: May 2016

The 127I or 125Te NMR spectra for (M(IO5(OH))2)5‐ (M: Cu, Ag, Au), (MO2(IO5(OH))2)6‐ (M: Ru, Os), (Co4I3O24H12)3‐, (MO2(TeO4(OH)2)2)6‐ (M: Os, Ru), and in addition for H5IO6, NaIO4, and (I(OH)6)+ are recorded in solution.
ChemInform Abstract: 73Ge NMR Spectra of GeO2 Dissolved in Water.
Authors: KUPCE E. , LUKEVICS E.
Published: May 2016

Despite the low solubility of GeO2 in H2O, a relatively narrow 73Ge resonance at ‐16.7 ppm is detected which is assigned to Ge(OH)4.
ChemInform Abstract: Phase Relations in the Pd‐Te System.
Authors: KIM W. S. , CHAO G. Y. , CABRI L. J.
Published: May 2016

The phase diagram of the title system is reinvestigated in the range 0‐50 at.% Te (XRD, DTA, electron probe microanalysis).
ChemInform Abstract: The Adsorption of Metal Oxyanions on Alumina
Authors: MULCAHY F. M. , FAY M. J. , PROCTOR A. , HOUALLA M. , HERCULES D. M.
Published: May 2016

(perrhenate, permanganate, molybdate, tungstate, chromate) is studied at pH 4.5.
ChemInform Abstract: Postsynthesis Modification of Aluminophosphates by Reaction with Silicon Tetrachloride.
Authors: BRINEN J. L. , WHITE M. G.
Published: May 2016

Hexagonal AlPO4 (designated as AlPO4‐5) is reacted with SiCl4 (1 atm) at 450‐750 °C and the structure, composition, and chemical properties of the modified materials thus obtained are studied as a function of reaction conditions (heating rate, temp., reaction time).
ChemInform Abstract: Synthesis, Structure and 77Se/119Sn NMR Spectroscopy of the New Polyselenide, Tris(tetraselenido)stannate(IV), (Sn(Se4)3)2‐.
Authors: HUANG S.‐P. , DHINGRA S. , KANATZIDIS M. G.
Published: May 2016

The title stannate, obtainable as outlined in the scheme or by reacting SnCl2·H2O with Na2Se5 in DMF (79% yield), crystallizes in the orthorhombic system, space group P21/c, Z=4.
ChemInform Abstract: Molten Lithium Nitrate‐Potassium Nitrate Eutectic: The Reaction of Bismuth Compounds.
Authors: KERRIDGE D. H. , ZELLIPOUR A.
Published: May 2016

In view of the lack of information, a systematic investigation of the reactions of BiCl3, Bi(NO3)3, and of bismuthate(V) is initiated in pure (neutral) LiNO3/KNO3 eutectic and in eutectic containing dissolved Lux‐Flood acids and bases.
ChemInform Abstract: Crystal Chemistry of Oxometallates of the Type Ba6Nd2Al4O15: New Results Concerning Ba4.5Ca1.5Nd2Fe4O15 (I) and Ba5CaSm2Fe4O15 (II).
Authors: RUETER I. + , MUELLER‐BUSCHBAUM HK. +
Published: May 2016

The title compounds (I) and (II) are prepared by heating pressed pellets of BaCO3, CaCO3, Ln2O3 (Ln: Nd, Sm), and Fe2O3 (1.
ChemInform Abstract: Effects of Solvent and Acid Concentration on the Absorption and Fluorescence Spectra of α,α‐Diaminonaphthalenes.
Authors: PAUL A. , SARPAL R. S. , DOGRA S. K.
Published: May 2016

The compounds (I) (with two coplanar amino groups), (II) (with twisted groups with respect to each other) and (III) (with non‐planar amino groups with respect to the naphthalene ring) are investigated in 11 different solvents.
ChemInform Abstract: Highly Enantioselective Elimination of meso‐Compounds.
Authors: KASHIHARA H. , SUEMUNE H. , KAWAHARA T. , SAKAI K.
Published: May 2016

Elimination of the triflates (I) with the chiral base (‐)‐DPA yields the bicyclo(3.3.0)octenes (II) in high optical purity, whereas the way via the chiral ester (IV) and an achiral base is less promising.
ChemInform Abstract: Pure Enantiomers from Retro‐Diels‐Alder Processes.
Authors: BECKMANN M. , HILDEBRANDT H. , WINTERFELDT E.
Published: May 2016

The use of the optically active cyclopentadienes (I) and (II) as chiral templates in the synthesis of cycloadducts is described, which after diastereo‐ and regioselective alkylation and subsequent thermal retro‐Diels‐Alder reaction give enantiomerically pure (> 98% e.e.) compounds such as (VII) or (IX).
ChemInform Abstract: Gas‐Phase Thermolysis of 6‐Cyclopropyl‐ (I) and 6‐Oxiranylpentafulvenes (VII): Novel Routes to Dihydroindenes and Vinylcyclopentadienes.
Authors: GRIESBECK A. G. , PETERS K. , PETERS E.‐M. , VON SCHNERING H. G.
Published: May 2016

Thermolysis of (I) leads to the mixture of dihydroindenes (II)‐(IV) which on treatment with dienophiles such as tetracyanoethylene, the triazoledione (V), or benzoquinone yields exclusively and stereospecifically 2:1 adducts of the dienophile and the predominant isomer (II), e.g. (VI) (space group P1 with Z=2).
ChemInform Abstract: Manganese(III) Acetate and Lewis Acid Mediated Cyclization of Olefinic β‐Keto Esters: A Comparative Study.
Authors: COLOMBO M. I. , SIGNORELLA S. , MISCHNE M. P. , GONZALEZ‐SIERRA M. , RUVEDA E. A.
Published: May 2016

The Mn(III) promoted cyclizations of the isomeric substrates (I) and (III) produce the two different compounds (II) and (IV), and they represent new examples of Mn(III) induced cyclization.
ChemInform Abstract: Synthesis of Heterocyclic Compounds by the Organotin Alkoxide Promoted Cleavage of γ‐Bromo β‐Lactones.
Authors: SHIBATA I. , TOYOTA M. , BABA A. , MATSUDA H.
Published: May 2016

The bromomethyl‐β‐lactams (I) are treated with the tin alkoxide (II) to produce the intermediates (III) which react with the heterocumulenes (IV) or (VIII), forming the corresponding heterocycles (V) and (IX).
ChemInform Abstract: A New Method for the Stereocontrolled Synthesis of Silyl Dienol Ethers Using (Naphthalene)chromium Tricarbonyl Catalyzed Isomerization.
Authors: SODEOKA M. , YAMADA H. , SHIBASAKI M.
Published: May 2016

Various dienol ethers such as (V) are synthesized in a highly stereoselective manner by rearrangement of the readily accessible Z‐butadiene derivatives, e.g. (III), using the title catalyst.
ChemInform Abstract: Photocatalytic Reactions of 1,3‐Butadiene over Water‐Adsorbed TiO2.
Authors: KODAMA S. , YAGI S.
Published: May 2016

The title reaction also occurs in the presence of TiO2 modified by oxygen or Pt.
ChemInform Abstract: First Direct Fluorination of Tyrosine‐Containing Biologically Active Peptides.
Authors: HEBEL D. , KIRK K. L. , COHEN L. A. , LABROO V. M.
Published: May 2016

The tyrosine‐containing biologically active peptide (I), which represents the essential part of the opiate peptide dermorphin (IV), is fluorinated with acetyl hypofluorite to give (IIa).
ChemInform Abstract: Vinylation of Allyl Alcohol by Acetylene and Vinyl Chloride in Super‐Basic Media.
Authors: TROFIMOV B. A. , OPARINA L. A. , LAVROV V. I. , PARSHINA L. N.
Published: May 2016

The reactions between allyl alcohol (I) and acetylene (II) or vinyl chloride (V) afford mixtures of allyl vinyl ether (III) and the isomeric (Z)‐1‐propenyl vinyl ether (IV), which are separated by distillation.
ChemInform Abstract: A Spacious Cyclophane Host for Inclusion Complexation of Steroids and (m.n)Paracyclophanes.
Authors: CARCANAGUE D. R. , DIEDERICH F.
Published: May 2016

Gallic acid derivatives, corticoids, and androgens form inclusion complexes with host (I) in D2O/CD3OH (1:1).
ChemInform Abstract: 7‐Hydrododecafluoroheptanethial Oxide.
Authors: MARKOVSKII L. N. , SLYUSARENKO E. I. , SHERMOLOVICH YU. G.
Published: May 2016

Starting from the polyfluorothioaldehyde (I) the title compound (V) is prepared via thermal decomposition of (IV).
ChemInform Abstract: Reaction of 1,1‐Dichloroalkyl Isocyanates with Nucleophilic Reagents. Synthesis of N‐(1,1‐Dichloroalkyl) Urethanes.
Authors: SAMARAI L. I. , BOIKO V. I. , GERTSYUK M. N.
Published: May 2016

The reaction between equimolar quantities of the 1,1‐dichloroalkyl isocyanates (I) and the alkanols or phenol (II) affords the novel‐type urethanes (III), whose structure is characterized by the unusual ‐CCl2‐NH‐CO‐ group.
ChemInform Abstract: A Convenient Preparation of 3‐Alkylcyclopentenones from Alkylcyclopentadienes.
Authors: COLLINS S. , HONG Y. , KATAOKA M. , NGUYEN T.
Published: May 2016

The hydroboration reaction of the cyclopentadienes (I) and (II) yields the alcohols (III) which are oxidized under Swern conditions to give the corresponding 3‐alkyl‐3‐cyclopenten‐1‐ones (IV).
ChemInform Abstract: Oxidative Cyclization of 3,7‐Dimethylenebicyclo(3.3.1)nonane on Reaction with Tetravalent Lead Compounds.
Authors: SERGUCHEV YU. A. , GUTSULYAK R. B. , KHOTKEVICH A. B. , KOROL' E. N.
Published: May 2016

The reaction between the title compound (I) and Pb(OAc)4 (II) affords 3,8‐diacetoxyhomoadamantane (III).
ChemInform Abstract: Modified Wittig Reactions Using Triethylamine and Lithium Halides: Synthesis of α,β‐Unsaturated Esters from Ketones and Ethyl Bis(trifluoroethyl) Phosphonoacetate.
Authors: RATHKE M. W. , BOUHLEL E.
Published: May 2016

The title reaction is successfully employed in the olefination of the ketones (Ia) ‐ (Id) to form the acrylates (IIIa) ‐ (IIId), whereas the sterically hindered representatives (Ie) and (If) do not react at all under these conditions.
ChemInform Abstract: Concurrent Configurational Modification in Conjugated Dienes. A New Pathway in the Isomerization of Alkadienes.
Authors: THYAGARAJAN B. S. , CHANDLER R. A.
Published: May 2016

The di(benzenesulfonyl)hexadiyne (I) reacts with 4‐methoxybenzenethiol (II) to yield the addition products (III) ‐ (V) which undergo substitution reaction with morpholine (VI), forming the morpholine derivative (VII).
ChemInform Abstract: Synthesis of syn‐Substituted Triptycenes via Heteroatom‐Directed Metalation.
Authors: KAWASE T. , ASAI N. , OGAWA T. , ODA M.
Published: May 2016

Lithiation of the triptycenes (I), (V), or (VIII) and subsequent reaction with dimethylformamide (II) produces the formyltriptycenes (III) and (IV), (VI) and (VII), or (IX).
ChemInform Abstract: Arylation of Furan Compounds by Aryldiazonium Salts.
Authors: OBUSHAK N. D. , GANUSHCHAK N. I. , LESYUK A. I. , DZIKOVSKAYA L. M. , KISILITSA P. P.
Published: May 2016

A novel and improved method for the preparation of the 3‐(5‐aryl‐2‐furyl)acrylic acids (III) is described.
ChemInform Abstract: Organic Syntheses with Transition‐Metal Complexes. Part 49. Pyrroles from a Aminocarbene Chromium Complex and Alkynes: Synthesis of a Novel β‐Tripyrane and a Cyclic β‐Trispyrrole.
Authors: AUMANN R. , HEINEN H.
Published: May 2016

The β‐tripyrane (VII) and the cyclic β‐trispyrrole (VIII) are obtained by means of a novel two‐step pyrrole synthesis from the iminocarbene complex (III) which adds alkynes such as (IV) to give the 1H‐pyrroles (V).
ChemInform Abstract: Reactions of 1‐Acetyl‐3‐(dicyanomethylene)‐1,3‐dihydro‐2H‐indol‐2‐one (II) with Amines.
Authors: YOUNES M. I.
Published: May 2016

Amine‐catalyzed reaction of (II) with alcohols yields quinolines such as (V).
ChemInform Abstract: A Novel Conversion of N‐Aryl‐N‐methoxyamides into N‐Arylhydroxamic Acids Using AlCl3/Thiol System.
Authors: KAWASE M. , KITAMURA T. , SHIMADA M. , KIKUGAWA Y.
Published: May 2016

The N‐methoxyamides (I) are treated with aluminum trichloride in ethanethiol or dimethyl sulfide to yield the N‐hydroxy derivatives (II) after acidic work‐up.
ChemInform Abstract: Reaction of 4‐Monosubstituted 1,3‐Dioxolanes with Dichlorocarbene.
Authors: KLYAVLIN M. S. , TKACHENKO T. K. , ZLOTSKII S. S. , RAKHMANKULOV D. L.
Published: May 2016

The reaction between the dioxolanes (I) and dichlorocarbene, which is known to afford products of insertion of dichlorocarbene into one of the C(2)‐H bonds, is reinvestigated.
ChemInform Abstract: Alkylation and Acylation of 5‐Hydroxy‐6‐oxo‐6H‐anthra(1,9‐cd)isoxazoles.
Authors: GORNOSTAEV L. M. , KUZNETSOV I. A. , VERKHOVODOVA D. SH. , GRITSAN N. P.
Published: May 2016

Alkylation of the title compounds (I) affords separable mixtures of the 5‐alkoxy derivatives (III) and their 6‐alkoxy isomers (IV).
ChemInform Abstract: Highly Polarizable Zwitter‐Ions for Nonlinear Optics: Synthesis, Structure and Properties of Phenoxide‐Pyridinium Derivatives.
Authors: BACQUET G. , BASSOUL P. , COMBELLAS C. , SIMON J. , THIEBAULT A. , TOURNILHAC F.
Published: May 2016

Two unsym. biaryls such as (V) possessing a 4‐ (or 3‐)pyridinium and a 4'‐phenoxy moiety are prepared using an original electrochemical method which is complementary to known purely chemical routes (yield of the methylation step not given).
ChemInform Abstract: Base‐Induced Conversion of N‐Alkoxypyridinium Salts Bearing a Formyl Group in Their Alkoxy Chain.
Authors: SLIWA H. , RANDRIA‐RAHARIMANANA C. , CORDONNIER G.
Published: May 2016

The formylmethyloxypyridinium nitrates (IV), prepared from pyridine N‐oxide (I), the α‐bromo aldehydes (II), and silver nitrate (III), are treated with 2,2,6,6‐tetramethylpiperidine to produce the 2‐hydroxyacylpyridines (V) as the result of a rearrangement.
ChemInform Abstract: A Facile One‐Step Synthesis of Novel Polysubstituted Pyridines via the Tandem‐Addition Rearrangement Hetaryne Reaction.
Authors: KHANAPURE S. P. , BIEHL E. R.
Published: May 2016

2,6‐Dimethoxypyridine (I) is lithiated and then coupled with chloromethyl methyl ether (II) to give 2,6‐dimethoxy‐3‐(methoxymethyl)pyridine (III) which is brominated with N‐bromosuccinimide, forming the 3‐bromopyridine (IV).
ChemInform Abstract: Base‐Induced Condensation of Phenols Joined by Amides to Ketones: A Synthesis of Hydroxylated Isoquinolinones and Derivatives.
Authors: FRIARY R. , SCHWERDT J. H. , SEIDL V. , TOPLISS J. G.
Published: May 2016

Hydrolysis of the benzamides (I) with potassium carbonate and subsequent treatment with acetic anhydride (II) result in cyclization and acetylation to produce the isoquinolinones (III).
ChemInform Abstract: Stereoselective Reduction of t‐Butyldimethylsiloxy Group of Ethyl 2‐Trichloromethyl‐4‐t‐butyldimethylsiloxy‐1,3‐dioxan‐4‐acetates.
Authors: HOMMA K. , MUKAIYAMA T.
Published: May 2016

Reduction of the isomeric siloxydioxaneacetates (I) or (IV) with triethylsilane results in the stereoselective formation of the cis‐isomers of (II).
ChemInform Abstract: Convenient Synthesis of 1,3‐Diaryl‐1,2,3,4‐tetrahydro‐5,7,7‐trimethyl‐4‐oxo‐2‐thioxo‐7H‐pyrano(2,3‐d)pyrimidines.
Authors: AHLUWALIA V. K. , KUMAR R. , KHURANA A. , BHATLA R.
Published: May 2016

The question whether the species (III) or the isomeric species (VIII) is formed when the thiobarbituric acids (I) react with acetone/Et3N or mesityl oxide (II) is clarified by independent synthesis of (III) from (I) via the intermediates (V).
ChemInform Abstract: Synthesis and Biological Activity of Tricyclic Analogues of Oxolinic Acid.
Authors: GLUSHKOV R. G. , DRONOVA L. N. , ELINA A. S. , POROKHOVAYA M. V. , PADEISKAYA E. N. , RADKEVICH T. P. , SHIPILOVA L. D.
Published: May 2016

The fused oxoquinolinecarboxylic acids and amides (III), (V), (VI), and (VIII) are prepared by common cyclization reactions.
ChemInform Abstract: Synthesis, Structure, and Ring‐Opening Polymerization of Strained Macrocyclic Biaryls: A New Route to High‐Performance Materials.
Authors: COLQUHOUN H. M. , DUDMAN C. C. , THOMAS M. , O'MAHONEY C. A. , WILLIAMS D. J.
Published: May 2016

Reductive cyclization of the dichloro compound (I) in the presence of tetrakis(triphenylphosphine)nickel, generated in situ, leads to the formation of the macrocyclic biaryl (II).
ChemInform Abstract: Synthesis and Structure of a 1λ5,4λ5‐Diphosphapentalene.
Authors: SILBERZAHN J. , PRITZKOW H. , LATSCHA H. P.
Published: May 2016

The stable diphosphapentalene (III) (space group P21/n, Z=2) synthesized as shown is characterized by X‐ray structure analysis and MS data.
ChemInform Abstract: Synthesis and Structure of Stibaindoles.
Authors: BUCHWALD S. L. , FISHER R. A. , FOXMAN B. M.
Published: May 2016

The stibaindoles (III) and (IV) are synthesized as shown for (III).
ChemInform Abstract: Synthesis of Tris(trifluoromethyl)gallium and Its Adducts.
Authors: GUERRA M. A. , MEHROTRA S. K. , DYER D. W. , LAGOW R. J.
Published: May 2016

The title compound (III) and its adducts (V) are synthesized as shown.
ChemInform Abstract: Ethyl Complexes of Zirconocene.
Authors: ALT H. G. , DENNER C. E.
Published: May 2016

The ethylene complex (I) reacts readily with a variety of substrates (R1OH (II), tBuSH, H2O (V), R2COOH (VII)) to give the ethyl complexes (III), (IV), (VI), and (VIII).
ChemInform Abstract: A Paramagnetic μ‐Methylene Complex with a Short Cr(III)‐Cr(III) Bond.
Authors: NOH S. K. , HEINTZ R. A. , JANIAK C. , SENDLINGER S. C. , THEOPOLD K. H.
Published: May 2016

The title complex (II) is obtained by decomposition of the electron‐poor compound (I) in solution and characterized by an X‐ray structure determination (P21/c, Z=4).
ChemInform Abstract: Transition‐Metal Complexes of P‐Rich Phosphanes and Silylphosphanes. Part 1. Transition‐Metal Complexes of Heptaphosphanortricyclanes R3P7 (R: Et, iPr).
Authors: FRITZ G. , SCHNEIDER H.‐W. , HOENLE W. + , VON SCHNERING H. G.
Published: May 2016

Reactions of the title compounds (I) with Cr(CO)5(THF) (II) in different molar ratios are investigated.
ChemInform Abstract: Silver(I) and Copper(I) Complexes of 1,6‐Cyclodecadiyne and 1,7‐Cyclododecadiyne.
Authors: GLEITER R. , KARCHER M. , KRATZ D. , ZIEGLER M. L. , NUBER B.
Published: May 2016

The reactions of the cycloalkynes (I) with Ag(I)‐ and Cu(I)‐triflate yield colorless polymeric 1:1 adducts in 80‐92% yield.
ChemInform Abstract: Polynuclear Metal Complexes with Bridging Carbene or Carbyne Ligands. Part 98. Tri‐ and Tetranuclear Metal Compounds with Ethylidyne or p‐Tolylmethylidyne Groups, and Having Both Cyclopentadienyl and Carbaborane Ligands.
Authors: GIMENO M. C. , STONE F. G. A.
Published: May 2016

The trimetal compounds (V) (yields 70‐86%) are prepared by treating the complexes (III) with carbyne‐W complexes of the type (IV) containing a carbaborane ligand as shown for the example (Va).
ChemInform Abstract: Formation of Optically Pure N‐Acyl‐N,N′‐dicyclohexylurea in N,N′‐Dicyclohexylcarbodiimide‐Mediated Peptide Synthesis.
Authors: SLEBIODA M. , WODECKI Z. , KOLODZIEJCZYK A. M.
Published: May 2016

The addition reaction of the optically pure N‐protected α‐amino acids (I) with DCC (II) yields the optically pure N‐acylureas (III).
ChemInform Abstract: A New Synthetic Route to Ubiquinones.
Authors: RUETTIMANN A. + , LORENZ P.
Published: May 2016

The ubiquinones (VIII) are prepared employing a new strategy: as key step, the Diels‐Alder reaction of trichloroethene (I) and the furan (II) is used for the construction of the quinone part, which after methanolysis and further reaction with cyclopentadiene (III) yields the adduct (IV).
ChemInform Abstract: Synthetic and Mechanistic Studies on Esperamicin A1 and Calicheamicin γ1. Molecular Strain Rather Than π‐Bond Proximity Determines the Cycloaromatization Rates of Bicyclo(7.3.1) Enediynes.
Authors: MAGNUS P. , FORTT S. , PITTERNA T. , SNYDER J. P.
Published: May 2016

In connection with mechanistic studies concerning the DNA cleaving properties of the antitumor antibiotics esperamicin and calicheamicin γ1, kinetic parameters and thermodynamic data of the cycloaromatization of bicyclic enediynes are evaluated and discussed.
ChemInform Abstract: Structure and Synthesis of (.+‐.)‐Caudoxirene, a New Spermatozoid‐Releasing and ‐Attracting Pheromone from the Marine Brown Alga Perithalia caudata (Phaeophyceae, Sporochnales). Part 5.
Authors: WIRTH D. , BOLAND W.
Published: May 2016

The synthesis of the title compound (IV) is described using the diastereoselective alkylation of the aldehyde derived from the alcohol (I) with the titanium reagent (II) as key step.
ChemInform Abstract: Problems of Synthesis and Thermal Work‐Up of Supraconducting Bismuth‐Strontium‐Calcium Cuprates
Authors: TRET'YAKOV YU. D. , OS'KINA T. E. , PUTLYAEV V. I.
Published: May 2016

Review: (45 refs.
ChemInform Abstract: Generation and Reactions of Silylenes in the Gas Phase
Authors: CHERNYSHEV E. A. , KOMALENKOVA N. G.
Published: May 2016

Review: (62 refs.
ChemInform Abstract: Structure of SnMo5O8 Containing Bioctahedral Mo10 Clusters.
Authors: GOUGEON P. , POTEL M. , SERGENT M.
Published: May 2016

Single crystals of the title compound are prepared by reaction of SnO2, MoO3, and Mo at 2030 K (sealed Mo‐crucible).
ChemInform Abstract: Rh2Sb with (anti‐)PbCl2‐Type Structure.
Authors: JEITSCHKO W. , ALTMEYER R. O.
Published: May 2016

Single crystals of the title compound are grown by annealing the elemental components in a NaCl/KCl flux (Rh:Sb:NaCl:KCl = 2.5:1.2:15:15; 800 °C, 5 weeks).
ChemInform Abstract: Additional In‐Depth Information Obtainable from the Energy Loss Features of Photoelectron Peaks: The Oxidation and Reduction of an Fe/Cr Alloy in Oxygen at Low Partial Pressures and Ultra High Vacuum.
Authors: CASTLE J. E. , KE R. , WATTS J. F.
Published: May 2016

It is demonstrated that the energy loss features within the XPS spectra, which have generally been regarded as a nuisance, can be used to obtain useful secondary information.
ChemInform Abstract: Characterization of Photochemically or Electrochemically Reduced Blue Titanium Dioxide.
Authors: MUELLER R. P. + , STEINLE J. , BOEHM H. P.
Published: May 2016

It is shown that the blue color of TiO2 (anatase or rutil), observed after reduction by UV irradiation in the presence of suitable hole scavengers (e.g.
ChemInform Abstract: Potentiodynamic Studies of Modified 9Cr‐1Mo Ferritic Steel in Sulfuric Acid and Seawater.
Authors: MODI O. P. , MUNGOLE M. N. , SINGH K. P.
Published: May 2016

The corrosion behavior of annealed and cold‐worked 9Cr‐1Mo ferritic steel modified with 0.198 wt.% V and 0.072 wt.% Nb is studied in 0.1‐5 N H2SO4 at 25 °C. The electrochemical parameters such as the critical current density, passivation current density, corrosion current density, and the passivation potential decrease with increasing H2SO4 concentration, while the corrosion potential increases.
ChemInform Abstract: Tetraphenylphosphonium Hexachloroarsenate, PPh4(AsCl6); Synthesis and Crystal Structure.
Authors: BEBENDORF J. , MUELLER U. +
Published: May 2016

The intense yellow title compound (III) can be prepared as outlined in the scheme or by introduction of Cl2 instead of O3 (86%).
ChemInform Abstract: Synthesis and Characterization of 18‐Molybdopyrophosphate Complex.
Authors: HIMENO S. , SAITO A. , HORI T.
Published: May 2016

The existence of a new yellow 18‐molybdopyrophosphate complex is ascertained in the solid state and solution.
ChemInform Abstract: Toward Molecular Charge‐Transfer Relays. A Three‐Dimensional Acceptor and Its Radical Anion.
Authors: MASLAK P. , AUGUSTINE M. P. , BURKEY J. D.
Published: May 2016

Information about the LUMO in the "three‐dimensional" acceptor molecule (III) is provided by the measurement of reduction potentials (cyclic voltammetry) of (III) (‐0.90 V) and the model ketones (II) (‐1.36 V) and (IV) (‐1.51 V), thus indicating a lowering of the LUMO in (III) by 0.31 eV in comparison to a hypothetical nonspiroconjugated model.
ChemInform Abstract: Metal Alkyl and Aryl Compounds. Part 44. Preparation and Structure of Methylsodium. Structure Determination Using NaCD3 Powders at 1.5 and 300 K by Neutron and Synchroton Radiation Diffraction.
Authors: WEISS E. , CORBELIN S. , COCKCROFT J. K. , FITCH A. N.
Published: May 2016

The title compound crystallizes as a new structure type in I222 with Z=16 showing elements of the MeLi and MeK structures.
ChemInform Abstract: Examinations in the Wittig System with Regard to an Ordering Concept of Alternative Principles.
Authors: BANDMANN H. , BARTIK T. , BAUCKLOH S. , BEHLER A. , BRILLE F. , HEIMBACH P. , LOUVEN J.‐W. , NDALUT P. , PREIS H.‐G. , ZEPPENFELD E.
Published: May 2016

Fundamental reflections are presented as to different effects on mechanistic pathways in chemical reactions.
ChemInform Abstract: The Production of Methacrylic Acid by the Vapor‐Phase Aldol Condensation of Propionic Acid with Formaldehyde.
Authors: AI M.
Published: May 2016

Whereas CH2=CH‐COOH is obtained in high yields from CH3‐COOH + HCHO (II) over V2O5‐P2O5 catalysts (96‐98 mol%), the yield of (III) does not exceed 39 mol%.
ChemInform Abstract: Oxygen Scrambling and Stereochemistry During the Trifluoroethanolysis of Optically Active 2‐Butyl 4‐Bromobenzenesulfonate (I).
Authors: DIETZE P. E. , WOJCIECHOWSKI M.
Published: May 2016

During the trifluoroethanolysis of (I), containing 18O in the nonbridging oxygens, scrambling of the oxygen label occurs.
ChemInform Abstract: Steric and Electronic Effects on the Conformations and Singlet Oxygen Ene Regiochemistries of Substituted Tetramethylethylenes. The Origin of the Geminal Effect.
Authors: CLENNAN E. L. , CHEN X. , KOOLA J. J.
Published: May 2016

The reactions of singlet oxygen with 22 allylically substituted tetramethylethylenes such as (I) are studied.
ChemInform Abstract: Intramolecular Diels‐Alder Reactions of Pyrazines with Alkynylphenyl Moieties as Side‐Chain Dienophiles.
Authors: HAIDER N. , VAN DER PLAS H. C.
Published: May 2016

The pyrazines (I), (IV) and (VII) react under neutral and acidic conditions to give tricyclic b‐ and c‐anellated pyridines.
ChemInform Abstract: Chemistry of Dicyclopropylcarbene and Related Intermediates in Dimethyl Sulfoxide.
Authors: FREEMAN P. K. , WUERCH S. E. , CLAPP G. E.
Published: May 2016

The ketones (I) are coupled with phenylsulfonylhydrazine (II) and subsequently treated with potassium hydride (III) to produce the salts (IV).
ChemInform Abstract: Photochemical Reactions. Part 152. Photochemistry of Acylsilanes: Photolysis and Thermolysis of Cyclopropyl Silyl Ketones.
Authors: SCHELLER M. E. , FREI B.
Published: May 2016

The photolysis of the title ketones (I), (VIII) or (XII) under π,π* excitation conditions yields the various compounds delineated in the scheme.
ChemInform Abstract: Radical Ion Probes. Part 1. Cyclopropylcarbinyl Rearrangements of Aryl Cyclopropyl Ketyl Anions.
Authors: TANKO J. M. , DRUMRIGHT R. E.
Published: May 2016

An established method is the use of intramolecular rearrangements for the experimental detection of electron‐transfer pathways in organic reactions in the case of free radicals.
ChemInform Abstract: 2‐(((p‐Nitrophenyl)sulfonyl)oxy)‐3‐keto Esters: Versatile Intermediates for the Preparation of 1,2,3‐Tricarbonyl Compounds.
Authors: HOFFMAN R. V. , KIM H.‐O. , WILSON A. L.
Published: May 2016

Reaction of the α‐nosyloxy β‐keto esters (I) with triethylamine generates the 1,2,3‐tricarbonyl derivatives (II) which are trapped with o‐phenylenediamine (III) to produce the quinoxalines (IV).
ChemInform Abstract: Reactions of Organic Anions. Part 173. Oxidative Cross‐Coupling of Enolates with Nitronate Anions Promoted by Chloride Anions.
Authors: WROBEL Z. , MAKOSZA M.
Published: May 2016

Treatment of a mixture of the diethyl malonates (I) and the nitroalkenes (II) with NaOEt generates malonate and nitronate anions.
ChemInform Abstract: Multistep Electron Transfer in Palladium‐Catalyzed Aerobic Oxidations via a Metal Macrocycle‐Quinone System.
Authors: BAECKVALL J.‐E. + , HOPKINS R. B. , GRENNBERG H. , MADER M. M. , AWASTHI A. K.
Published: May 2016

An oxidizing triple catalytic system is developed successfully which consists of Pd(OAc)2 + benzoquinone + a metal macrocycle as the third component; the latter used to reoxidize hydroquinone (formed in the catalytic cycle) by molecular O2.
ChemInform Abstract: Dimethylethylamine‐Alane and N‐Methylpyrrolidine‐Alane. A Convenient Synthesis of Alane, a Useful Selective Reducing Agent in Organic Synthesis.
Authors: MARLETT E. M. , PARK W. S.
Published: May 2016

Reaction of the lithium aluminum hydride (II) with tertiary amines such as (I) forms the corresponding alane‐amine complexes (III), together with trilithium aluminum hexahydride (IV).
ChemInform Abstract: The Reaction of 2,4‐Dinitrofluorobenzene with Aniline, Cyclohexylamine, and 1,2‐Diaminocyclohexanes in Aprotic Solvents. A New Approach to the “Dimer Mechanism”.
Authors: NUDELMAN N. S. , MONTSERRAT J. M.
Published: May 2016

In toluene the title reaction with aniline shows third‐order dependence on the amine concentration.
ChemInform Abstract: Asymmetric Synthesis of 2‐, 3‐, and 4‐Methyloctanoic Acids.
Authors: SONNET P. E. , GAZZILLO J.
Published: May 2016

The regioisomeric chiral methyloctanoic acids (R)‐(VIII), (R)‐(XIV), and (R)‐(XVII) are prepared via optical resolution of the 2‐methylated carboxylic acids (±)‐(III).
ChemInform Abstract: Synthesis of Dithiocarbamates and Study of Their Radioprotective Activity.
Authors: STROGONOVA L. T. , BOL'SHAKOVA S. A. , TUZHILKOVA T. N. , AMOSOVA S. V. , IVANOVA N. I. , TARASOVA O. A. , AL'PERT M. L.
Published: May 2016

The dithiocarbamic acid salts (V), (VIII), or (XIII) and the esters (X) or (XI) are prepared as shown in the reaction scheme.
ChemInform Abstract: Synthesis and Reactions of β‐Silyloxyacylcyclopropanes. Trimethylsilyl Halide ‐ Zinc Halide Induced Cyclopropylcarbinyl Rearrangement.
Authors: MOISEENKOV A. M. , CZESKIS B. A. , IVANOVA N. M. , NEFEDOV O. M.
Published: May 2016

The α‐siloxyvinylcyclopropanes (I) are coupled with the aliphatic aldehydes (II) in the presence of zinc dichloride to produce the β‐siloxy ketones (III).
ChemInform Abstract: Synthesis and Structure of Isomeric syn‐ and anti‐2,4‐Diphenylhydrazones of 2‐Acetamido 5‐Substituted Benzophenones.
Authors: YAVORSKII A. S. , PAVLOVSKII V. I. , ANDRONATI S. A. , DVORKIN A. A. , GIFEISMAN T. SH. , SIMONOV YU. A.
Published: May 2016

Acylation of the syn‐ and anti‐2,4‐dinitrophenylhydrazones (I) with bromoacetyl bromide (II) produces the title compounds (III) under retention of the configuration.
ChemInform Abstract: The Synthesis of Selectively Substituted p‐Diacetylcalix(4)arene.
Authors: NO K. , HONG M.
Published: May 2016

Alkylation of calix(4)arene (I) with methyl iodide (II) in the presence of a base yields the dimethyl ether (III) which undergoes Friedel‐Crafts acylation with the acid chlorides (IV), forming the diketones (V).
ChemInform Abstract: The Effect of Metal Chelate Complexation on the Reactivity and Absorption Spectra of 1,2‐Naphthoquinones: New Types of Near‐IR‐Absorbing Metal Complex Dyes.
Authors: YOSHIDA K. , OGA N. , KOUJIRI T. , ISHIGURO M. , KUBO Y.
Published: May 2016

The already known reaction (desulfo substitution) of sulfonate (I) with prim. arylamines such as (II) is efficiently promoted by Ni(II) ions (less by Cu(II) and Co(II)) as is the reaction with the dialkylanilines (IV) to give (III) and (V), respectively.
ChemInform Abstract: Photocycloaddition of Cyclohex‐2‐enones to Tetramethoxyethylene: Formation of 2,2,3,3‐Tetramethoxy‐1‐oxaspiro(3,5)non‐5‐enes.
Authors: CRUCIANI G. , RATHJEN H.‐J. , MARGARETHA P.
Published: May 2016

The spiro compounds (IIIa), (IIId) or (VIa) are predominantly or exclusively formed in the title reaction of the cyclohexenones (I), (V) with tetramethoxyethylene (IIa).
ChemInform Abstract: A General Synthetic Route to 2,2′:5′,2′′‐Terpyrrole, 2,5‐Bis(2‐pyrryl)thiophene, and Alkyl‐Substituted Analogues.
Authors: MERRILL B. A. , LEGOFF E.
Published: May 2016

The thiazolium halide catalyzed reaction of the pyrrolecarboxaldehyde (I) with divinyl sulfone (II) produces the 1,4‐diketone (III).
ChemInform Abstract: An Unusual Fischer Indole Synthesis with 4‐Keto Acids: An Indole Incorporating the Terminal Hydrazine Nitrogen.
Authors: EICHEN CONN R. S. , DOUGLAS A. W. , KARADY S. , CORLEY E. G. , LOVELL A. V. , SHINKAI I.
Published: May 2016

The phenylbenzylhydrazine hydrochloride (III), prepared by reaction of the benzyl chloride (I) with phenylhydrazine hydrochloride (II), is coupled with the γ‐keto acids (IV) to give a mixture of the N‐benzylindoles (V), together with the indoles (VI).
ChemInform Abstract: Synthesis of a Series of 5‐Methyl‐1H‐imidazole‐4‐ylmethyl Sulfides.
Authors: KMONICEK V. , VEJDELEK Z. , PROTIVA M.
Published: May 2016

Among the title products prepared only (IIIa) and (Va) show some pharmacological activity in tests which are considered predictive of antidepressant action.
ChemInform Abstract: Synthesis of 2‐Azolylcycloalkanols.
Authors: MURABAYASHI A. , MAKISUMI Y.
Published: May 2016

Cycloalkanones such as (IV), prepared from the cycloalkene oxides (I), undergo coupling reaction with Grignard compounds, e.g. (V), to produce the corresponding alcohols, e.g. (VI) or (VII), with predominance of the cis‐isomers.
ChemInform Abstract: Synthesis of Key Carbazoles. Intermediates for Polymethoxyellipticines and Olivacines.
Authors: HALL R. J. , JACKSON A. H. , OLIVEIRA‐CAMPOS A. M. F. , QUEIROZ M.‐J. R. P. , SHANNON P. V. R.
Published: May 2016

Formylation of the carbazole (I) with N‐methylformanilide (II) yields the aldehyde (III) which is coupled with aminoacetaldehyde diethyl acetal (IV) to produce the corresponding unstable Schiff base.
ChemInform Abstract: Regioselective Formation of Hydroxy Lactams from Pyridine‐2,3‐dicarboximides and Their Cyclodehydration to Pyrido(2′,3′:3,4)pyrrolo‐Fused Heterocyclic Systems.
Authors: HITCHINGS G. J. , VERNON J. M.
Published: May 2016

On NaBH4 reduction of the title compounds (I), predominantly the carbonyl group adjacent to the pyridine N‐atom is reduced; Grignard reaction of (I) yields exclusively the products (V).
ChemInform Abstract: Preparation of a New Chiral 5,6‐Dihydropyridinium Synthon.
Authors: DIEZ A. , HUANG P.‐Q. , GRIERSON D. S. , HUSSON H.‐P. , RUBIRALTA M.
Published: May 2016

Silylation of (S)‐(‐)‐ethyl lactate (I) with the chlorosilane (II) and subsequent amination with ammonia (IV) yield the siloxypropanamide (V) which is converted into the N‐acetoxymethyl derivative (VIII) by consecutive reaction with formaldehyde (VI) and acetic anhydride (VII).
ChemInform Abstract: Hydrazino‐Bridged Annulenes. Part 7. Synthesis of Diethyl 6H‐9b,9c‐Diazacyclopenta(cd)phenalene‐5,7‐dicarboxylate.
Authors: FLITSCH W. , LEWINSKI U. , TEMME R. , WIBBELING B.
Published: May 2016

Vilsmeier reaction of the pyrrolopyridine (III) does not take place at the α position of the pyrrole moiety as expected and the aldehyde (V) is formed instead as an inseparable mixture of E/Z isomers.
ChemInform Abstract: Diethyl Pyrrolo(1,2‐b)cinnoline‐6,8‐dicarboxylate, a Product of an Anomalous Vilsmeier Reaction.
Authors: FLITSCH W. , LAUTERWEIN J. , LEIMKUEHLER M. + , LEAVER D. , LEWINSKI U. , MATTES R. , TEMME R. , WIBBELING B.
Published: May 2016

The title compound (III) is formed as a by‐product of the Vilsmeier reaction of the pyrrolopyridine (I) (cf.
ChemInform Abstract: Formation and Reactivity of Highly Stabilized Carbanions and Enolates by Pd‐Catalyzed Alkylation of Heterocyclic Compounds.
Authors: SAKAKIBARA T. , KUME T. , SHIMOHARA K. , FUJISHIMA H. , HARA S. , SHIMODA T.
Published: May 2016

5‐Bromo‐3‐phenylisoxazole (I) undergoes coupling reaction with malononitrile (II) or the cyanoacetates (V) in the presence of sodium hydride and a Pd(II) catalyst to produce the salts (III) or (VI).
ChemInform Abstract: Pteridines. Part 94. Synthesis and Characteristics of 5,6‐Dihydro‐6‐(1,2,3‐trihydroxypropyl)pteridines: Covalent Intramolecular Adducts.
Authors: SOYKA R. , PFLEIDERER W. , PREWO R.
Published: May 2016

Condensation of the triaminopyrimidine (II) with (Ia) or (Ib), followed by neutralization, yields the enantiomeric intramolecular adducts (+)‐(III) (space group P21) or (‐)‐(III), respectively.