bluuebunny/crossref_metadata_2025 huggingface dataset:
Lipoprotein abnormalities: A potential consequence of chronic kidney disease
Authors: Ahi Rajinderjit Singh , Singh Sandeep , Kumar Umesh , Paul Basharat Azhar
Published: August 2024

: Chronic kidney disease (CKD) is marked by kidney damage or a glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m for at least three months, regardless of the underlying etiology. When a variety of renal problems are present, albuminuria defined as an albumin-to-creatinine ratio >30 mg/g in two out of three spot urine samples can serve to determine kidney failure.The estimated global rate of CKD is 13.4%. Nearly every aspect of biological life involves lipids. A few of these include acting as hormones or as precursors to hormones, providing energy, storing function and metabolic fuels, acting as functional and structural molecules in bio-membranes and forming insulation to aid in nerve transmission or prevent heat loss. The blood contains a variety of lipoproteins. They are chylomicrons, very-low density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL), in descending sequence of increasing density. Less dense lipoproteins result from lower protein/lipid ratios. Although some lipoproteins carry cholesterol in its natural "free" alcohol form (the cholesterol-OH group facing the water surrounding the particles), all lipoproteins contain identical amounts of cholesterol. Other lipoproteins carry cholesterol in the form of fatty acyl esters, sometimes referred to as cholesterol esters. Triacylglycerol and cholesterol, which were not employed in the production of bile acids, are converted by the liver into VLDL molecules.

The aim of the study was to assess the Lipid levels in CKD and study the correlation between eGFR (which is a marker of severity of CKD) and lipid levels in CKD.

Thepresent study was an observational study. The study was conducted over a period of six months on 180 patients. Blood samples were obtained in Becton Dickinson's commercially available red-capped tubes vacutainers (BD). After that, blood samples were left undisturbed at room temperature for 15-30 minutes to coagulate. For 5 minutes, the tubes were centrifuged at 3000 rpm. After centrifugation, the sample solution (serum) was transferred to a fresh polypropylene tube with a Pasteur pipette. Lipid profile and serum creatinine were done on fully automated SYSMEX BX-3010.

Our results show that mean and standard deviation of serum cholesterol, serum triglycerides, HDL, VLDL and LDL with -value between males and females in the different stages of CKD shows a statistically significant difference between stage II, III B, IV and stage V.

The present study highlights the progressive increase in serum cholesterol, serum triglycerides, VLDL, LDL levels as CKD advances through its stages. A progressive decline in HDL levels as CKD also advances through its stages. The correlations between eGFR and various biomarkers in the stages of CKD shed light on the complex interactions between renal function, lipid metabolism.
Sigma performance evaluations for clinical chemistry and immunoassays in a tertiary care hospital laboratory based on Clinical Laboratory Improvement Amendments (CLIA) 1988 and 2024 Guidelines
Authors: Bais Bhavana , Singh Kriti , Tripathi Varijendra
Published: August 2024

Sigma metrics, implemented by clinical laboratories, utilize the performance of assays to evaluate both precision and accuracy by considering the recommended total allowable error (TEa). The study aims to evaluate the performance of 48 analytes (chemistry and immunological) performed in a tertiary care hospital laboratory and compare them with the TEa recommended by CLIA 1988 and 2024 guidelines.

This study, conducted at the Biochemistry Department of Medanta Hospital, Lucknow, Uttar Pradesh, India, utilizes retrospective data of the period January 2023 to December 2023 to analyze the performance of 48 assays in terms of precision (percentage of coefficient of variation (CV%) from the internal quality control (IQC) data) and accuracy (Bias %) from the monthly data of external quality assessment services (EQAS). 28 clinical chemistry and 20 immunoassays were performed on an automated VITROS XT 7600 Integrated chemistry analyzer. Sigma scores were calculated and analyzed using a standard formula, which includes Bias%, CV%, and TEa for each assay.

Based on TEa source from CLIA 1988 and 2024, for clinical chemistry assays - 64%, 46% showed sigma performance score of >6.0; 27%, 43% showed sigma performance score between 3.0 to 5.9; and 9%, 11% of showed sigma performance score of below 3.0 respectively. For immunoassays, based on TEa source from CLIA 2024, 55% showed a sigma performance score of >6.0, 35% showed a sigma performance score between 3.0 to 5.9, and 10% showed a sigma performance score of below 3.0.

This study showed that about 90% of clinical chemistry and immunoassays produced excellent results on the sigma scale. The analysis helped to identify the root causes of the low performance of a few assays with a sigma score below 3.0 and the performance improvement steps undertaken.
Entropy in Different Black Hole: A Case Study
Authors: Kumari Anjali , Dubey Om Prakash , Singh Sumita
Published: August 2024

Purpose of Study: The study's objective is to investigate the function of entropy in black holes, with a particular emphasis on the ways in which entropy aids in the comprehension of the properties of various varieties of black holes, such as Schwarzschild, Kerr, and charged black holes (Reissner-Nordström and Kerr-Newman). The objective of the investigation is to examine the unique entropy characteristics that are associated with each form of black hole within the context of black hole thermodynamics.
Methodology: The entropy of black holes is examined through a theoretical approach that utilizes the principles of thermodynamics and information theory. The analysis entails a comparison of the entropy properties of Schwarzschild, Kerr, and charged black holes, taking into account their distinctive characteristics and the implications for black hole thermodynamics.
Results: The analysis demonstrates that the inherent properties of each form of black hole are directly correlated with their distinctive entropy characteristics. Schwarzschild black holes, Kerr black holes, and charged black holes exhibit unique entropy patterns, which contribute to a more exhaustive comprehension of black hole thermodynamics and provide more profound insights into their thermodynamic behavior.
Applications: The results have substantial implications for the advancement of theoretical physics, particularly in the field of black hole thermodynamics. The development of more precise models and predictions regarding black hole behavior can be facilitated by an understanding of the entropy characteristics of various varieties of black holes. This knowledge has the potential to inform future research in quantum gravity and cosmology.
Acknowledgment of a Refusal to Hire as Unjustified: Relevant Issues of Theory and Practice
Authors:   Professor of the Department of Labor Law of the Law Faculty of the Lomonosov Moscow State University, Zabramnaya Elena Yu.
Published: August 2024

The article is devoted to the analysis of judicial practice in cases of appealing refusal to hire and related norms of the Labor Code of the Russian Federation regulating the issues of concluding an employment contract.
STRATEGI GURU AKIDAH AKHLAK DALAM MEMBENTUK KEPRIBADIAN MUSLIM PADA PESERTA DIDIK KELAS VIII DI MTSN MODEL BANGKALAN
Authors: Kamiliya Zuhrotul
Published: August 2024

Character education can be built for each individual, and can also solve problems in everyday life and can a lso improve the quality of human life in various aspects of daily life. In this study, the researcher used a descriptive qualitative method with the type of field research, namely by coming directly to the Bangkalan Model State Madrasah Tsanawiyah. The data acquisition technique used was through observation, interviews, and documentation. The analysis technique in this study is through the stages of data reduction, data presentation, and drawing conclusions.
 
Abstrak
Pendidikan karakter dapat dibangun bagi setiap individu, dan juga dapat memecahkan masalah dalam kehidupan sehari-hari dan juga dapat meningkatkan kualitas hidup manusia dalam berbagai aspek kehidupan sehari-harinya. Peneliti menggunakan metode kualitatif deskriptif dengan jenis penelitian field research, yaitu dengan datang secara langsung ke MTsN Model Bangkalan, sedangkan untuk teknik perolehan data yang digunakan melalui observasi, wawancara, dan dokumentasi
REFLEKSIFITAS METODE FREE DISCOVERY LEARNING
Authors: Rifqi Naflah
Published: August 2024

Multidimensional PAI learning requires a strategic method. With short portions, 3 hours of lessons the teacher must be good at combining teaching methods that are able to improve students' cognitive, affective and psychomotor competencies. The demands of digitization, an independent curriculum and the characteristics of the Z-generation that always require innovation are joint homework. One solution is discovery learning. The author raises one of its branches, namely Free Discovery learning, which is synonymous with student-centered. Starting from planning, processing and learning direction is determined independently by students. This study aims to test whether FDL (Free Discovery learning) can cover the many demands of PAI learning above with reflexivity, weaknesses and strengths from cognitive, affective and psychomotor aspects. The author uses a qualitative descriptive method with questionnaire data collection techniques and pre-test post-test. The results of FDL in class IX PAI Islamic Middle School Sunan Giri showed a prominent increase in terms of affective, then psychomotor and a slight increase in cognitive. Some of the factors that most influence this are teacher competence, short lesson hours and the non-linearity of student presentation material with cognitive tests conducted by the teacher.
 
Abstrak
Pembelajaran PAI yang multidimensional memerlukan metode strategis. Dengan porsi singkat yakni 3 jam pelajaran dalam satu pekan, maka guru harus pandai mengkombinasikan metode ajar yang mampu meningkatkan kompetensi kognitif, afektif, dan psikomotorik siswa. Tuntutan digitalisasi, kurikukum merdeka dan karakteristik generasi-Z yang selalu membutuhkan inovasi menjadi PR bersama. Salah satu solusinya adalah discovery learning. Penulis mengangkat satu cabangnya yakni Free Discovery learning, yang identic dengan student-centered learning. Mulai dari perencanaan, pengolahaan dan arah belajarnya ditentukan mandiri oleh siswa. Penelitian ini bertujuan menguji apakah FDL (Free Discovery learning) dapat meng-cover banyaknya tuntutan pembelajaran PAI di atas dengan refleksifitas (kelemahan dan kelebihan) berdasar aspek koginitf, afektif dan psikomotorik. Penulis menggunakan metode deskriptif kualitatif dengan teknik pengumpulan data questioner dan pre-test post-test. Hasil dari FDL pada pembelajaran PAI kelas IX SMP Islam Sunan Giri menunjukkan adanya peningkatan yang menonjol dari segi afektif dan psikomotor, namun sayangnya hanya sedikit peningkatan pada segi kognitif. Beberapa faktor yang paling mempengaruhi hal tersebut adalah kompetensi guru, jam pelajaran yang singkat dan ketidak linieran materi presentasi siswa dengan uji kognitif yang dilakukan guru.
KEWAJIBAN MENUNTUT ILMU: Kajian Tafsir Tematik
Authors: Ilmi Ziyadatul , Siham Aqilla Armintya
Published: August 2024

The  Humans and Jinn are commanded to worship Allah swt. And there is no way and no way to worship Allah swt. properly except with syar'i knowledge, namely the ladder to Allah swt. and he too is the way to His pleasure. Islam cannot be enforced except by knowledge. Islam circulates and is preached in the midst of society with knowledge, and Muslims are people of knowledge, because of all the rules and teachings contained in Islam is based on and based on knowledge. Al-Qur'an from beginning to end is a science that contains many lessons that very important and precious to us, and we are not allowed to talk about this religion except with knowledge. Science has a high position in Islam. Because of that people who have knowledge occupy a high position in the sight of Allah SWT. All Muslims are required to seek knowledge so that their faith does not go astray, their worship is correct, and their behavior is in accordance with the Shari'a. Seeking knowledge is one of the obligations for every Muslim as long as life is still conceived in the body.
Abstrak
Manusia dan Jin diciptakan untuk menyembah Allah swt. Dan tidak ada jalan serta cara untuk menyembah Allah swt. dengan baik kecuali dengan ilmu syar'i, yaitu tangga menuju Allah swt. dan dia juga adalah jalan menuju keridhaan-Nya. Islam tidak dapat ditegakkan kecuali dengan ilmu. Islam beredar dan diberitakan di tengah-tengah masyarakat dengan ilmu, dan umat Islam adalah orang yang berilmu, karena semua aturan dan ajaran yang terkandung dalam Islam didasarkan dan didasarkan pada ilmu. Al-Qur'an dari awal sampai akhir adalah ilmu yang banyak mengandung pelajaran yang sangat penting dan berharga bagi kita, dan kita tidak boleh membicarakan agama ini kecuali dengan ilmu. Ilmu memiliki kedudukan yang tinggi dalam Islam. Karena itu orang yang berilmu menempati kedudukan yang tinggi di sisi Allah SWT. Semua umat Islam diwajibkan untuk menuntut ilmu agar imannya tidak menyimpang, ibadahnya benar, dan perilakunya sesuai dengan syariat. Menuntut ilmu merupakan salah satu kewajiban bagi setiap muslim selama hayat masih dikandung badan
PENGARUH PEMBELAJARAN BLENDED LEARNING TERHADAP PRESTASI BELAJAR SISWA PADA MATA PELAJARAN PAIBP PADA SAAT COVID-19
Authors: Ula Ayu Fatichatul
Published: August 2024

Wabah covid-19 memberikan dampak yang besar terhadap seluruh lini kehidupan, tidak terkecuali pada lini pendidikan. Pemerintah pada akhirnya memutuskan untuk melakukan proses pembelajaran melalui Pembelajaran Jarak Jauh (PJJ). Namun meski begitu, dalam pelaksanaannya masih banyak kendala yang dihadapi, terlebih pada media yang digunakan. Karena melalui jarak jauh maka pembelajaran harus membutuhkan alat bantu berupa smartphone sebagai media pembelajarannya. Bagi siswa yang memilik taraf ekonomi menengah kebawah tentu hal ini menjadi kendala besar, yang pada akhirnya membuat peserta didik malas mengikuti pembelajaran sehingga prestasi belajar mereka menurun. Oleh karenanya SMP 1 Nguling yang memiliki permasalahan tersebut pada akhirnya memutuskan untuk melakukan pembelajaran blended learning melalui WhatsApp dan tatap muka terbatas dengan mematuhi protokol kesehatan yang berlaku. Penelitian ini berfokus pada tiga hal, yaitu  1) gambaran proses pembelajaran blended learning, 2) prestasi belajar siswa pada mata pelajaran PAIBP 3) pengaruh pembelajaranblended learning terhadap prestasi belajar siswa. melalui penelitian kuantitatif dengan pendekatan expofacto, penelitian ini hendak menguji apakah blended learning berpengaruh terhadap prestsi belajar siswa. Ari hasil penelitian menggunakan analisis deskriptif diketahui bahwa pembelajaran blended learning berada pada kategori sedang. Begitu pula dengan prestasi blajar siswa berada pada kategori sedang. Melalui uji regresi sederhana ditemukan bahwa pembelajaran blended learning berpengaruh terhadap prestasi belajar siswa dengan arah pengaruh yang negatif dengan uji t yang menunjukkan nilai thitung sebesar 2,521 > ttabel sebesar 2,032 dengan besaran pengaruh sebesar 15,7%.
Kata Kunci: Model pembelajaran; Blended learning; Prestasi belajar
UNCOVERING THE VEIL OF FORGETFULNESS IN LEARNING: Review In The Book Of Ta'lim Muta'allim
Authors: Fiyona Putri , Hafidzi Anwar
Published: August 2024

Forgetting, a reality that is often a scourge for knowledge seekers, becomes the main focus in the 12th chapter of Imam Al-Zarnuji's Ta'lim Muta'allim. This article delves into a deeper understanding of the causes of forgetting from the perspective of the classic book. The study identifies two main categories of causes of forgetting: internal and external factors. Internal factors include excessive busyness, anxiety, and sadness, as well as the consumption of certain foods. On the other hand, external factors include committing sins, seeing astonishing things, and passing through certain places.  Furthermore, this article elaborates on the mechanisms behind each factor, explaining how they can interfere with the process of storing and retrieving information in memory. The discussion does not stop at identifying the causes, but offers practical solutions to overcome them. Through an in-depth analysis of Kitab Ta'lim Muta'allim, this journal makes a valuable contribution to understanding and overcoming forgetfulness, especially for students and knowledge seekers. This comprehensive understanding is expected to help them achieve success in gaining knowledge.
 
Abstrak
Lupa, realitas yang kerap kali menjadi momok bagi para penuntut ilmu, menjadi fokus utama dalam bab ke-12 Kitab Ta'lim Muta'allim karya Imam Al-Zarnuji. Artikel ini menyelami pemahaman mendalam mengenai penyebab lupa berdasarkan perspektif kitab klasik tersebut. Kajian ini mengidentifikasi dua kategori utama penyebab lupa: faktor internal dan eksternal. Faktor internal meliputi kesibukan, kegelisahan, dan kesedihan yang berlebihan, serta konsumsi makanan tertentu. Di sisi lain, faktor eksternal mencakup perbuatan dosa, melihat hal-hal yang mencengangkan, dan melewati tempat-tempat tertentu.  Lebih lanjut, artikel ini menjabarkan mekanisme di balik masing-masing faktor, menjelaskan bagaimana hal-hal tersebut dapat mengganggu proses penyimpanan dan pengambilan informasi dalam memori. Pembahasan ini tidak berhenti pada identifikasi penyebab, tetapi menawarkan solusi praktis untuk mengatasinya. Melalui analisis mendalam Kitab Ta'lim Muta'allim, jurnal ini memberikan kontribusi berharga dalam memahami dan mengatasi lupa, khususnya bagi para pelajar dan penuntut ilmu. Pemahaman yang komprehensif ini diharapkan dapat membantu mereka dalam mencapai kesuksesan dalam menimba ilmu pengetahuan.
Moderasi Beragama pada Portal Keislaman
Authors: Achmad Tohari  , Neneng Mujlipah
Published: August 2024

This paper discusses the phenomenon that exists in many digital media that use religion as a tool to boost the position of the press, many portals or even media display da'wah segments that many people easily understand, but some media are only used for propaganda of mere interests. The method used in this research is qualitative combined with literature review research on sources and journals that are still relevant to the research. This research explains about Islamic portals in their narratives that have experienced significant development, especially Islamist media whose impression dominates digital space in Indonesia, the data used in this case uses Michel Foucault's power relations theory as a media discourse analysis knife. The findings in the study are that the knowledge built by islami.co media is more about disseminating discourse or in power theory, namely disciplinary power, something that shows that there is a power relationship between helping, instilling, and controlling the body, so it can be understood that islami.co has the authority for knowledge aimed at understanding religious moderation on Islamic portals.
Huruf Muqaṭṭa’ah: Penafsiran Ulama Kalam dan Ulama Sufi dalam Perspektif Semiotika Pierce
Authors: Qodriatinnisa Raden Rifa , Wildan Taufiq  , Dadan Rusmana
Published: August 2024

Interpretation as a human product is greatly influenced by the science and orientation of the interpreter. This leads to different interpretations of the Qur'an. A calamite interprets the Qur'an according to his level of knowledge as a mutakallim, as well as a Sufi. This article will show a comparison of the interpretation of the letter muqattha’ah between Imam Al-Maturidi in the book of Tafsir Ta’wilat Ahli As-Sunnah who is the figure of a calam scholar and Ibn Ajibah’s interpretation in his book Al-Bahru al-Madid fi Tafsir Al-Qur’an Al-Mayid as a Sufi scholar. The method applied in this research is qualitative using library studies, research based on library data. Then the data was analyzed using Peirce's semiotic triad theory. This article will describe how the interpretation of Imam Al-Maturidi as a fictional scholar and Ibn Ajibah as a Sufi scholar against the letter muqattha’ah that is located on the opening of the letter. It will begin with the introduction of the basic theory of semiotics Peirce, the understanding of the letters muqatta’ah, as well as the interpretations of letters muqa’ah by Imam al-Muridi and Ibnu Ajibha. Then this interpretation will be applied to the triadic theory Peirces, in the form of representations, objects and interpretations. It can be concluded that a mufasir is very influential as an interpreter of signs or symbols found in the Qur'an. As in the interpretation of Al-Maturidi and Ibnu Ajibah, the Maturidi who is a mutakallim is more inclined to the submission of the meaning to Allah.
Konflik Batin Tokoh Utama Dalam Novel Hotel Miramar Karya "Najib Mahfudz" Kajian Psikologi Sastra
Authors: Suciana Nabila , . Mashyur , Sumarna Luqman
Published: August 2024

Novel adalah karangan prosa yang panjang mengandung cerita seseorang dengan orang disekelilingnya dengan menonjolkan, konflik, sifat, watak setiap pelaku. Adapun menurut Esten (2013:7) novel adalah sebuah karya fiktif yang dibuat pengarang dengan menggunakan tokoh imajinatif latar dan alur buatan. Pengungkapan nilai-nilai kemanusiaan juga dibahas secara mendalam dan sistematis. Lebih jauh menjelaskan bahwa novel merupakan pengungkapan dari fragmen kehidupan manusia (dalam jangka yang lebih panjang) dimana terjadi konflik-konflik yang akhirnya menyebabkan terjadinya perubahan jalan hidup antara para pelakunya.
Najib Mahfuzh merupakan penulis novel atau cerpen yang terkenal di dunia Arab. Karya-karyanya mempunyai warna tersendiri karena karyanya selalu diawali dengan kata-kata yang indah dan  menarik, Najib Mahfuzh berasal dari Kairo, Mesir. Lulusan jurusan filsafat islam di Universitas Kairo ini menggemari dunia tulis menulis semenjak duduk dibangku perkulihaan. Karya-karyanya mencakup 70 cerita pendek, 46 karya fiksi, sekitar 30 naskah drama dan lebih dari 10 Novel. Salah satu karya Najib Mahfuzh yaitu Hotel Miramar yang mampu membuat banyak pembaca ikut terbawah perasaan dalam kehidupan yang dirasakan oleh wanita yang menginginkan kebebasan yang terdapat  di dalam cerita novel tersebut.
الصراع الداخل للشخصية الرئيسية في رواية "فندق ميرامار" لنجيب محفوظ (دراسة علم النفس الأدبي)
Authors: Solehah Mirfatus , . Mashyur , Sumarna Luqman
Published: August 2024

الرواية هي تركيبة نثرية طويلة تحتوي على قصة شخص مع الأشخاص من حوله من خلال إبراز الصراع والطبيعة والشخصية لكل ممثل. اما حسب 2013, Esten)) الرواية هي عمل خيالي تم إنشاؤه بواسطة مؤلف باستخدام شخصية خيالية وخلفية اصطناعية ومؤامرة. يتم أيضًا مناقشة الكشف عن القيم الإنسانية بعمق وبشكل منهجي. وتوضح كذلك أن الرواية هي كشف عن أجزاء من حياة الإنسان (على المدى الطويل) حيث تحدث النزاعات التي تؤدي في النهاية إلى تغييرات في طريقة الحياة بين الجناة.
نجيب محفوظ روائي أو كاتب قصة قصيرة معروف في العالم العربي. أعماله لها لونها الخاص لأن عمله يبدأ دائمًا بكلمات جميلة و جذب, نجيب محفوظ من القاهرة، مصر. تخرج في تخص الفلسفة الإسلامية بجامعة القاهرة، وقد استمتع بالكتابة منذ أن كان في الكلية. تشمل أعماله 70 قصة قصيرة و 46 عملاً خياليًا وحوالي 30 مسرحية وأكثر من 10 روايات.  من أعمال نجيب محفوظ فندق ميرامار القادر على جعل الكثير من القراء يتابعون أدنى المشاعر في الحياة التي تشعر بها النساء اللواتي يرغبن بالحرية الموجودة في قصة الرواية.
تحكي رواية فندق ميرامار قصة فتاة قروية يتيمة تريد الحرية في حياتها ورغبة قوية في تغيير مصيرها. أدى الإكراه على الزواج المرتب من رجل لم يكن محبوبًا وإهانة الأسرة التي كان يتلقاها دائمًا إلى مغادرة القرية وأخيراً جلبت قصة الفتاة التي ربها جده إلى نزل يملكه صديق والده في الإسكندرية، ميرامار. أثناء وجودها في ميرامار، اكتسبت الفتاة الخبرة والتعليم والحب، لكن هذه الفتاة غالبًا ما عانت أيضًا من التبعية والقولبة والتنمر والعنف أثناء وجودها في ميرامار.
 
الشخصية الرئيسية هي دور مهم يجب أن تمتلكه شخصية في القصة, الشخصية الرئيسية هي في الأساس شخصية يتم سردها غالبًا في القصة، والشخصية الرئيسية موجودة دائمًا في كل حدث وغالبًا ما توجد في كل صفحة من صفحات الكتاب المعني. كتاب القصة المعني هو في شكل قصص قصيرة وروايات. بينما الشخصيات في الرواية هم زهر (الشخصية الرئيسية)، شقيق زهر، مادمي ماريانا (صديقة والد زهر)، ألييا، أمير وجدي، حسني علام، منصور باهي ، سرحان البحيري.
Kepribadian dan Aktualisasi Diri Tokoh Utama dalam Novel Zayni Barakat Karya Jamal Al-Ghitani
Authors: Rahmawati Isnaini , Prasedia Titik
Published: August 2024

Tujuan penelitian ini adalah mengungkapkan kepribadian dan aktualisasi diri tokoh utama menurut teori Humanistik Abraham Maslow. Dalam mencapai hal tersebut dilakukan dua analisis utama. Pertama, analisis kepribadian Zayni Barakat yang meliputi bagaimana cara ia memenuhi kebutuhan hierarki dari yang terendah hingga yang tertinggi. Kedua, apa saja wujud aktualisasi yang telah di capai Zayni Barakat ketika menjadi muthasib sekaligus gubernur Kairo. Teori yang di gunakan dalam penelitian ini adalah kepribadian humanistik Abraham Maslow, melalui studi kepustakaan dan metode kualitatif. Tahap analisis dilakukan dengan mengumpulkan data yang relevan dengan teknik baca-catat, kemudian dianalisis dengan teori kepribadian Humanistik, setelah itu data di sajikan secara deskriptif. Hasil penelitian menunjukkan bahwa. Pertama, zayni Barakat dapat memenuhi kebutuhan hierarkinya. Kebutuhan tersebut mencakup; kebutuhan fisiologis, rasa aman, rasa cinta dan keberadaan, penghargaan, hingga kebutuhan aktualisasi diri. kedua, Zayni dapat mewujudkan pencapaiannya ketika ia menjadi seorang muhtasib, meski dalam proses pemenuhannya mengalami banyak hambatan. Namun dengan sikap positif dan juga kegigihannya, ia dapat mengatasi hambatan-hambatan tersebut. Dan melalui usaha-usaha juga pergorbanan yang dilakukannya tersebut, Zayni Barakat dapat meraih aktualisasi dirinya.
Optimizing Child Development Given Roscoe Pound's Social Interest Theory (Study at Alif Islamic Daycare)
Authors: Alfina Fitria Tahta , Mukarromah Fahira Lailatul , Ariany Nina , Rifqi Muhammad Jazil
Published: August 2024

This study aims to examine how to optimize children's development in the context of the Social Interest Theory promoted by Roscoe Pound, with a focus on studies studied at Alif Islamic Daycare. In the context of daycare institutions, social interaction, and care are the keys to understanding how social factors influence children's development. This research adopts a qualitative approach, in which the data collection method uses interviews, observation, questionnaires, and document analysis to explore the impact of applying social interest theory at Alif Islamic Daycare. The main participants targeted in the research are care staff, parents, and children attending Alif Islamic Daycare. The data is analyzed by referring to the concepts contained in social interest theory such as the influence of the social environment on morality, the balance between individual, public, and social interests in the concept of general security as well as social interests which refer to society's standards for individual life. The research results show that a social interests-oriented approach in managing Alif Islamic Daycare makes a significant contribution to optimizing children's development. Alif Islamic Daycare prioritizes Islamic values so that they can have a positive impact on children's social, emotional, and cognitive development. A supportive, safe, and comfortable environment as well as Islamic norms are a strong foundation for the development of children's personalities at Alif Islamic Daycare
Utilization of Quizizz as an Online Learning Media for Early Childhood
Authors: Karim Nur Adha
Published: August 2024

This research aims to see the benefits of Quizizz as an online learning media for young children. The approach used is quantitative with a quasi-experimental design. The research sample consists of 142 early childhood children aged 5-6 years at the Al-Amin Batuangkar Kindergarten. The research lasted for three months, from January to March 2024. Data collection techniques include observation, structured interviews with teachers, and questionnaires to measure students' perceptions of using Quizizz. The collected data is analyzed using descriptive and inferential statistics to test the research hypothesis. The research results show that the use of Quizizz significantly increases interest in learning and understanding number material in Arabic in young children. Children who used Quizizz show higher increases in learning outcomes compared to the control group who used conventional learning methods. Based on these findings, it is recommended that educators and educational institutions consider integrating Quizizz or similar platforms in the learning curriculum for early childhood, considering its positive impact on children's motivation and learning outcomes. This research makes an important contribution to the field of early childhood education, especially in the use of educational technology to improve the quality of learning.
STEAM-based Batik Activities as an Effort to Stimulate Cognitive Abilities
Authors: Hidayati Novi , Widadiyah Qorina
Published: August 2024

The low cognitive abilities of early childhood and the lack of variety of media and methods used in learning mean that this research aims to look at STEAM-based batik activities in improving cognitive abilities in early childhood. This research approach is a mixed method with a focus on group B children aged 5-6 years in one of the kindergartens in Gebangudik District, Cirebon Regency. Data was collected using observation techniques and interviews. Interview data and observations of STEAM-based batik activities using a qualitative approach. Observational data on children's cognitive abilities will be analyzed using a quantitative approach. The results of this research show that STEAM-based batik activities can improve children's cognitive abilities with a percentage gain of 39% in the Starting to Develop category to 70% in the Developing According to Expectations category, especially in the ability to solve problems, think critically, develop reasoning power, and make decisions. Because this batik activity is modified into an activity that can make children explore their environment because this batik activity goes through several steps, namely patterning, wiping and batiking. Steps of activities that are integrated with the STEAM approach can improve the ability to solve problems, think critically, develop reasoning power, and make decisions.
La exigencia de titulación para trabajar en el sector privado y público
Authors: López Aguado Paula
Published: August 2024

Para la realización de las funciones propias de determinados puestos de trabajo, en ocasiones se requiere estar en posesión de ciertos conocimientos académicos y profesionales. Esto impide a otros trabajadores acceder a determinados empleos y obstaculiza la libre competencia y concurrencia de empresas. Por ello, la legislación establece la reserva de ley y limitaciones a la imposición de requisitos de titulación. Este estudio tiene como objetivo, a partir de un análisis de la normativa y de las resoluciones judiciales al respecto, examinar qué disposiciones pueden establecer el requisito de titulación, cómo se debe motivar esta exigencia y que debería valorar el orden jurisdiccional competente antes de proceder a la extinción de los contratos de trabajo por carencia de la titulación o habilitación administrativa estipulada.
ANALISIS DESAIN USER INTERFACE PADA SITUS WEB DAN APLIKASI VIDIO
Authors: Rifqi Husnul Khuluq , Solicitor Costa Rica El Chidtian Aileena
Published: August 2024

Analisis User Interface pada situs web dan aplikasi Vidio adalah evaluasi tampilan dan pengalaman pengguna. Tujuannya meninjau kualitas desain dan memastikan pengguna dapat dengan mudah dan efektif menggunakan situs web dan aplikasi. Faktor-faktor seperti tata letak, warna, font, kontras, dan navigasi harus diperhatikan. Tata letak yang baik memudahkan pengguna menemukan informasi. Warna dan font harus mudah dibaca dan tidak mengganggu penglihatan. Kontras yang tepat penting untuk kejelasan informasi. Navigasi yang intuitif memudahkan pengguna menavigasi situs web dan aplikasi. Analisis UI juga memperhatikan pengalaman pengguna keseluruhan, termasuk pendaftaran, pencarian konten, dan interaksi fitur lain. Pengalaman pengguna yang baik meningkatkan kepuasan dan penggunaan situs web dan aplikasi secara teratur. Analisis UI penting untuk meningkatkan kualitas desain dan pengalaman pengguna di situs web dan aplikasi Vidio.
ANALISIS PERBANDINGAN LOGO PERTAMINA DENGAN LOGO KARYA ARTIFICIAL INTELLIGENCE MENGGUNAKAN LOGO AI
Authors: Nara Gabriel Antonio Nicholas
Published: August 2024

Logo merupakan salah satu karya desain yang penting karena logo bertugas sebagai wajah dari sebuah brand. Sebuah logo harus mampu mewakili karakteristik  dari brand-nya agar dapat membedakan diri dari brand lainnya. Seperti brand lainnya, Pertamina juga merupakan sebuah brand besar yang memiliki sebuah logo. Logo tersebut dibuat oleh sebuah agensi desain yang ditangani oleh beberapa desainer logo sehingga dapat menciptakan hasil yang bagus dan efektif. Akan tetapi dalam pembuatan logo tersebut menghabiskan biaya yang cukup tinggi, sedangkan di internet sudah tersedia begitu banyak situs pembuat logo otomatis  berteknologi  artificial intelligence seperti LogoAi yang memerlukan biaya lebih rendah dibandingkan membayar sebuah agensi desain. Tetapi setelah dianalisa lebih dalam menggunakan prinsip dasar desain logo menurut Jacob Cass, terungkap bahwa logo yang dibuat menggunakan LogoAi hanya dapat menciptakan sebuah logo yang sederhana dan serbaguna saja. Untuk menciptakan sebuah logo unik , yang tidak hanya bagus secara visual, tetapi juga dapat bertahan lama dan mengandung makna yang dapat mewakili sebuah brand perusahaan, diperlukan kreatifitas dan kemampuan memberikan makna yang hanya dimiliki oleh manusia dan belum dapat digantikan oleh teknologi. Oleh karena itu, logo Pertamina yang sesungguhnya sudah termasuk efektif karena sudah memenuhi semua prinsip dasar desain apabila dibandingkan dengan logo buatan LogoAi.
PERANCANGAN MEDIA EDUKASI MENGGUNAKAN AUGMENTED REALITY MENGENAI PAKAIAN TARI BEDHAYA SUKAHARJA
Authors: Mataram Sayid , Nanprahita Lovely Ayunda
Published: August 2024

The preservation of culture in Indonesia, exemplified through its diversity in each region, particularly in traditional dances such as Tari Bedhaya Sukaharja, faces significant challenges in terms of understanding and preservation by the millennial generation. Their role is crucial as agents of preservation and bearers of local values. To engage the millennial generation, augmented reality (AR) technology is considered a fitting solution. AR is an innovative and interactive tool that can help millennials understand and preserve cultural heritage in an engaging and relevant way. This study employs the structured waterfall method, which includes steps for planning, design, development, testing, evaluation, and implementation. The study sample was chosen at random, with the goal of laying a solid foundation for understanding the impact of AR technology in enhancing the understanding and awareness of the millennial generation ages 12-18 regarding the preservation of Indonesian cultural heritage, specifically in the context of Tari Bedhaya Sukaharja.
Enhancing Gastrointestinal Diagnostics with YOLO-Based Deep Learning Techniques
Authors: Yang Yuanfang , Jin Yuhui , Tian Qiyuan , Yang Yahe , Qin Weijian , Ke Xiaolan
Published: August 2024

Gastrointestinal (GI) tract disorders, ranging from benign polyps to aggressive forms of cancer, pose significant health challenges globally. Early detection and precise classification of these conditions are crucial for effective treatment and improving patient survival rates. This study employs the Hyper-Kvasir dataset, a comprehensive collection of endoscopic images, to develop deep learning models that harness the power of the YOLO (You Only Look Once) architecture for real-time detection and classification of GI abnormalities. The focus is on overcoming inherent challenges such as class imbalance and limited annotated data availability. Advanced machine learning strategies, including data augmentation and semi-supervised learning, are utilized to enhance the model's performance. Our experiments demonstrate notable improvements in the detection of pre-cancerous lesions and other GI abnormalities, confirming the potential of integrating AI into endoscopic practices to support clinicians, reduce diagnostic errors, and contribute to more accurate and timely diagnoses. The implications of these findings are significant, offering a pathway to more reliable diagnostic processes and ultimately, better patient management in gastroenterology.
Citation Analysis of Global Research on Data Literacy
Authors: Nwagwu Williams Ezinwa
Published: August 2024

This study analyzes the scholarly landscape of data literacy through citation and co-citation analyses of documents, sources, and authors. Using Scopus data and VOSviewer, the study identifies significant contributions and thematic trends. A minimum criterion of 10 citations per document was applied, filtering the dataset to 205 documents, with a focus on 81 interlinked documents. Citation analysis covered document, source, and author metrics, while co-citation analysis examined cited authors, sources, and references. The study found 997 documents on data literacy, narrowed down to 205 significant ones, with 81 interlinked documents showing a high average citation rate. Key sources included the ACM International Conference Proceeding Series and Teachers College Record, and prominent authors like Ellen B. Mandinach and Kim Schildkamp emerged as central figures. Data literacy research spans fields like education, sociology, and information science, highlighting its interdisciplinary nature. The study's focus on citation metrics may introduce selection bias, emphasizing widely cited works. Future research could explore less-cited but influential works and broader datasets to mitigate biases. Policymakers can use these insights to integrate data literacy into educational curricula and design targeted professional development programs. Promoting interdisciplinary collaboration and supporting open access to scholarly literature can enhance data literacy initiatives. This study provides a comprehensive citation and co-citation analysis of data literacy research, offering valuable insights into key contributions and thematic trends, informing policy and practice, and underscoring the importance of data literacy in contemporary education and society.
Comparative Review of Multi-Criteria Decision-Making Methods
Authors: Muhammed Abdulkabir , Błaszczyk, Ph.D. Paweł
Published: August 2024

Performance analysis of companies is critical for decision-makers in the financial sector, particularly when resources are limited. This study investigates the properties of various Multi-Criteria Decision-Making (MCDM) methods, critically comparing their results in evaluating the performance of consumer goods companies listed on the Nigerian Stock Exchange (NSE). The analysis utilizes financial ratios, with weights derived using Buckley's Column Geometric Mean Method, a fuzzy ranking approach. The study concludes by comparing TOPSIS, VIKOR, and ELECTRE methods, determining the final rankings of these companies, and interpreting these rankings based on financial ratios over a five-year period (2016-2020).
Efficacy and Safety in Dogs Following Administration of an Alphavirus RNA Particle Canine Influenza H3N2 Vaccine
Authors: Classe Haley Marie , Dant Jennifer , Mogler Mark , Stachura Ken , LaFleur Rhonda , Xu Zach , Tarpey Ian
Published: August 2024

Canine influenza virus (CIV) H3N2 causes a highly contagious respiratory disease in dogs and has been the source of outbreaks across North America since 2015. An injectable RNA Particle (RP)-CIV H3N2 vaccine has been developed to protect dogs against this disease. To demonstrate efficacy, dogs were randomized into two treatment groups, then vaccinated subcutaneously twice, 21 days apart, with a placebo vaccine (n = 20) or a RP-CIV H3N2 vaccine (n = 20). Three weeks later, dogs were challenged intranasally with virulent CIV H3N2 and observed daily for 10 days for clinical signs of disease. Nasal swabs were also collected daily to evaluate shedding of the challenge virus. Ten days post-challenge, dogs were euthanized, and the lungs were examined for consolidation. RP-CIV H3N2 vaccination demonstrated a significant reduction in duration of clinical signs, duration and amount of virus shed, lung consolidation, and the incidence of suppurative pneumonia. To evaluate safety, dogs from multiple geographic regions were vaccinated subcutaneously, 3-4 weeks apart, with a RP-CIV H3N2 vaccine and observed for adverse events for 14 days after each administration. The RP-CIV H3N2 vaccine was deemed safe, with lethargy being the most reported adverse event at a rate of 1.6%.
Peran Pemerintah Kabupaten Ponorogo dalam Penanggulangan Pengemis dan Pengamen Perspektif Siyâsah Dusturiyâh
Authors: Nisrina Alya
Published: August 2024

Beggars and buskers are a social phenomenon in Ponorogo Regency whose existence has created a new phenomenon that needs serious handling. Many responses emerged from several groups of people, some were concerned, but quite a few were less sympathetic towards the existence of beggars and buskers who often appeared on the streets. The aim of this research is to describe the regulations and their implementation as well as the duties and functions of the Regional Government in handling beggars and buskers in Ponorogo Regency. This research method is qualitative research with a type of field research. In conclusion, the role of the Regional Government in dealing with beggars and buskers in Ponorogo Regency has been maximized in terms of control and guidance, however, there are still many beggars and buskers who come from outside the city which has resulted in an increasing number of beggars and buskers coming from outside the city. beggars and buskers in Ponorogo Regency. In Siyâsah Dusturiyâh, the mandate of the Regional Government has not been carried out effectively because there is no infrastructure such as rehabilitation places for beggars and buskers.
WITHDRAWN: Comparative study of the insecticidal activity of essential oils of four spontaneous and domestic plants on wheat weevils Sitophilus oryzae
Authors: Asma HALMOUNE , Mourad NGADI , Abdessamad AIT BENLABCHIR , Khalid KHFIF , Hamza ELFINOU , Abdelhamid ZAID , Lhoussaine EL RHAFFARI
Published: August 2024

The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder: evidence from patients and models of the disease
Authors: Iuso Arcangela , Zhang Fangfang , Dorn Tatjana , Gnutti Barbara , Anikster Yair , Kuebler Sarah , Ahrens-Nicklas Rebecca , Gosselin Rachel , Rahman Shamima , Durst Ronen , Zanuttigh Enrica , Güra Miriam , Poch Christine , Meier Anna , Laugwitz Karl-Ludwig , Schüller Hans-Joachim , Messias Ana , Sibon Ody , Finazzi Dario , Rippert Alyssa , Li Dong , Truxal Kristen , Nandi Deipanjan , Lampert Brent , Yeo Mildrid , Gardham Alice , Nissan Batel , Cederboim Smadar Horowitz , Moretti Alessandra
Published: August 2024

Background
PPCS deficiency disorder (PPCS DD) is an ultra-rare, autosomal recessive form of dilated cardiomyopathy (DCM) caused by pathogenic variants in PPCS, which encodes the enzyme catalyzing the second step in the coenzyme A (CoA) biosynthesis pathway. To date, only six patients worldwide have been identified. In this study, we report on six additional patients. We shed light on the functional aspects of DCM in PPCS DD and evaluate therapeutic approaches to boost CoA levels both in vitro and in vivo.
Methods and Results
Whole-exome sequencing identified causative variants in PPCS in six additional individuals presenting with DCM and a spectrum of phenotypes, including neuromuscular signs and neurologic deterioration. Western blotting analyses demonstrated destabilizing effects of identified variants on the PPCS protein. Microplate-based assessment of CoA showed reduced levels of the coenzyme in patient-derived fibroblasts, cardiac progenitor cells, and cardiomyocytes. Functional investigation of DCM in cardiac cells and heart patches revealed defects in contractile function and arrhythmic events, which were partially rescued by pantethine. Long-term clinical assessment showed encouraging benefits in pantethine-treated patients.
Conclusion
Our study expands the genetic and clinical spectrum of PPCS deficiency disorder, identifying six new cases with diverse phenotypes. Functional investigations reveal reduced CoA levels and dysfunction in patient-derived cardiac cells. Pantethine treatment shows promise in partially rescuing DCM phenotypes, both in vitro and in patients. However, complete reversal may require early intervention. These findings underscore the importance of timely diagnosis and treatment in PPCS DD. Future research should focus on optimizing pantethine supplementation and exploring additional therapies to enhance CoA levels and cardiac function in affected individuals.
Quasi-experimental analyses of the effect of ADHD on education performance in youths across sexes and ancestry
Authors: Castro-de-Araujo Luis FS , Zhou Daniel (Yi) , Su Mei-Hsin , Kramer Sydney , Loughnan Robert , Neale Michael C
Published: August 2024

Attention-deficit hyperactivity disorder (ADHD) is prevalent in children and associated with lower education performance. This association is often obtained from observational studies, which have limited ability to identify causal relationships. Knowledge of causes is useful, because it delineates intervention avenues more clearly, but research into causation in childhood is hindered by ethical and practical limitations to randomized clinical trials. The present study uses twin study designs and polygenic risk scores (PRS) to investigate the causal relationship between ADHD symptoms and poor educational performance. We combined family-based direction of causation modeling and Mendelian randomization (MR) approaches and applied them to ABCD study data for improved causal inference. The models used necessarily make assumptions about either horizontal pleiotropy, or the level of individual-specific confounding factors. Results support the hypothesis that ADHD symptoms have a causal effect on educational performance, and vice versa. No heterogeneity related to sex was found, nor moderation of causal estimates by gender. These findings highlight the complex interplay between ADHD and educational outcomes and emphasize the need for larger sample sizes in future research.