bluuebunny/crossref_metadata_2025 huggingface dataset:
Manalagi Apple Peel Kombucha Coating Method As A Natural Preservatif on Beef
Authors: Lestari Kinanti , Lita Zakaria  , Vania Rifda Violeta
Published: January 2025

Beef is one of the main commodities in the food industry. Beef must undergo a preservation process so that the beef is protected from contamination by microorganisms to maintain their quality. Manalagi apple peel kombucha contains organic acids and phytochemical substances that can inhibit antimicrobial activity. The research used an experimental method with three formulations which were differentiated based on the concentration of apple peel in kombucha namlely FKA, FKB and FKC. Fresh beef samples were coated with each kombucha formulation and incubated for 6 hours and then tested for preference by 30 panelists and compared with the control. The results of the hedonic test showed that the panelists preferred beef that had been coated with FKA kombucha because it had a color that was not much different from the color of fresh beef. Meanwhile, the panelists preferred the odor of beef that had been coated with FKC kombucha because it had a fresher odor and was not smelly when compared to the control. Likewise, panelists preferred the texture of beef that had been coated with FKB and FKC kombucha because it felt the softest and most tender when compared to the control.
Prevalence and morphometric analysis of the accessory mental foramina in Arab and Kurdish Iraqi populations using cone beam computed tomography
Authors: Taha Omar Basheer , Nawi Mohamad Arif Awang , Abdullah Johari Yap , Yusof Asilah
Published: January 2025

Purpose: Evaluation of the presence and morphology of the accessory mental foramina (AMF) before performing dental implants or other surgical procedures is crucial to prevent damage to the inferior alveolar neurovascular bundle and the associated complications. The aim of this study was to determine the prevalence and morphology of AMF in Arab and Kurdish Iraqi populations.

Methods: Cone beam computed tomography images of 400 subjects (200 Arabs, 200 Kurds) were collected from radiology archives. RadiAnt DICOM software (Medixant, Poland) was used for image analysis. The prevalence, location, shape, and size of AMF were determined. Chi-square test for differences and descriptive statistics were performed using IBM SPSS version 26.

Results: The prevalence of AMF was found in 6.25% of the subjects of both populations. AMF was observed in 3.5% of the Arab population and in 9% of the Kurdish population, both exhibited no significant difference between males and females. There was a significant difference in the prevalence of AMF between the two groups. Among the Kurds, AMF was most commonly positioned below the mental foramen (MF), while among the Arabs, it was equally distributed between below and at the same level as the MF. The oval shape was most prevalent among the Arabs, whereas oval and irregular shapes were the most common among the Kurds. In the Arab population, the mean width and length of the AMF were 1.38 mm and 1.43 mm, respectively. In the Kurdish population, the mean width and length of the AMF were 1.26 mm and 1.19 mm, respectively.

Conclusion: Awareness of anatomical variations, including the presence of AMF, is important in planning surgical interventions of the mandible, to help prevent complications that could arise from inadequate preoperative assessments. This study represents the most extensive research on AMF within Iraq's two largest ethnic groups of the country, the Arabs and Kurds.
Major Geopolitical Changes in the Persian Gulf Region: the Rise of China
Authors: Sargsyan Knarik
Published: January 2025

China has emerged as a dominant economic player in the Gulf region, demonstrating a proactive policy in the region. China's expanding economic and political involvement in the Gulf region indicates the successful application of Chinese soft power and the growing interest of the region's states towards Beijing. The Gulf Cooperation Council (GCC) states have shown keen interest in China's long-term economic investments. Chinese investments entered the region when these countries aimed to diversify their economies as part of national development visions. The GCC countries have achieved significant progress within the framework of the "One Belt One Road Initiative".
Չինաստանը Պարսից ծոցի տարածաշրջանում դարձել է գերիշխող տնտեսական դերակատար՝ գործուն քաղաքականություն վարելով տարածաշրջանի երկրների հետ: Չինաստանի տնտեսական և քաղաքական հարաճուն դերը Ծոցի տարածաշրջանում վկայում է այս երկրներում չինական փափուկ ուժի հաջող կիրառման մասին, ինչպես նաև ի ցույց է դնում նրանց հետաքրքրությունը Պեկինի նկատմամբ: Ծոցի համագործակցության խորհրդի (ԾՀԽ) երկրները հետաքրքրված են Չինաստանի երկարաժամկետ տնտեսական ներդրումներով: Չինական ներդրումները եղան այն ժամանակ, երբ այս երկրները ձգտում էին դիվերսիֆիկացնել իրենց տնտեսությունը՝ որպես ազգային զարգացման ծրագրերի մաս: Նրանք գրանցել են մեծ առաջընթաց «Մեկ գոտի, մեկ ճանապարհ» նախաձեռնության շրջանակում:
Китай стал доминирующим экономическим игроком в регионе Персидского залива, демонстрируя проактивную политику в регионе. Расширяющееся экономическое и политическое участие Китая в регионе Персидского залива указывает на успешное применение китайской «мягкой силы» в регионе и растущий интерес государств региона к Пекину. Страны Совета сотрудничества арабских государств Персидского залива (ССАГПЗ) проявили большой интерес к долгосрочным экономическим инвестициям Китая. Китайские инвестиции стали поступать в регион, когда эти страны стремились диверсифицировать свою экономику в рамках концепции национального развития. Страны Персидского залива добились значительного прогресса в рамках инициативы «Один пояс, один путь».
Funcionamiento Familiar y Factores de Riesgo en el Desarrollo de Trastornos del Comportamiento en Adolescentes
Authors: Fernández Mangia Karla , Silva Paredes Christian
Published: January 2025

La presente investigación tuvo por objetivo general identificar la relación entre funcionamiento familiar y factores de riesgo en el desarrollo de trastornos del comportamiento en adolescentes. La metodología empleada fue de enfoque cuantitativo, alcance descriptivo correlacional, corte transversal y diseño no experimental. Se usaron los siguientes instrumentos: escala de cohesión y flexibilidad (FACES III) y cuestionario para la detección de los trastornos del comportamiento en niños y adolescentes (ESPERI), se contó con la participación de 109 adolescentes de ambos sexos entre 14 a 16 años. Los hallazgos más significativos fueron los siguientes: el 80,07% de los adolescentes tuvieron un funcionamiento familiar disfuncional, mientras que el 41,3% presentó un nivel leve en los factores de riesgo en el desarrollo de los trastornos del comportamiento. Por lo que al realizar la prueba Chi cuadrado de Pearson se encontró un coeficiente de relación de 69,89a   y un valor de significación bilateral de 0,157. Por consiguiente, la conclusión más relevante es que no existe relación entre funcionamiento familiar y factores de riesgo en el desarrollo de trastornos del comportamiento, esto se debió a la influencia de factores protectores, tales como, la presencia de modelos a seguir positivos, el apoyo de maestros o mentores y redes de apoyo entre pares que contrarrestaron los efectos negativos del mal funcionamiento familiar.
Contabilidad creativa: una mirada crítica. Revisión de literatura
Authors: Mite Albán María Teresa , Narváez Cumbicos José Gonzalo , Cantos Lucas Pablo Antonio , Andrade Garófalo Carmen Aracely
Published: January 2025

La contabilidad ha enfrentado diversos desafíos desde sus inicios, siendo uno de los más importantes los criterios para la estimación y registro contable. Aunque estos criterios son esenciales para la autonomía del profesional contable, también representan un riesgo, ya que pueden facilitar la manipulación de los estados financieros para beneficiar a la empresa ante ciertos interesados. A pesar de la existencia de Normas de Información Financiera, su flexibilidad puede dar lugar a la llamada "contabilidad creativa", donde las empresas alteran su presentación económica para atraer inversiones y mejorar su posición financiera. Esta práctica puede comprometer la calidad y credibilidad de la información financiera, afectando tanto la toma de decisiones internas como externas. La globalización también influye en este fenómeno, ya que impulsa a las empresas a ser más competitivas, lo que puede llevar a aprovechar vacíos normativos. Este estudio se centró en un análisis bibliométrico de publicaciones sobre contabilidad creativa entre 2010 y 2020, utilizando bases de datos científicas como Scopus. Se identificaron 30 artículos en revistas de alto impacto que abordan esta temática, destacando que solo tres se centran en tendencias de publicación. A partir de estos hallazgos, se recomienda establecer métodos de control más robustos para mitigar los efectos negativos de la contabilidad creativa y asegurar que los estados financieros reflejen con precisión la realidad económica de las empresas.
Propuesta para optimizar la implementación de la Estrategia de Cuidado Integral Centrado en las Personas en el CESFAM Las Américas, Comuna de Talca
Authors: Cornejo Oróstica Patricio
Published: January 2025

En 2020, el Ministerio de Salud de Chile implementó la Estrategia de Cuidado Integral Centrado en las Personas (ECICEP) para la promoción, prevención y manejo de la cronicidad en contexto de multimorbilidad, basada en el Modelo de Atención Integral de Salud (MAIS). Ante la implementación de esta estrategia, se planteó la pregunta sobre cómo optimizar su proceso en un CESFAM. La hipótesis fue utilizar herramientas de Sistemas de Información Geográfica (SIG), para lo cual se realizó un estudio cuantitativo en el CESFAM Las Américas, en Talca. Los resultados incluyeron la geolocalización de pacientes en distintos grupos (G1, G2, G3), representados mediante mapas de calor y mapas de activos territoriales. Como conclusión, se propuso mejorar el proceso operativo de implementación de la ECICEP mediante el uso de SIG, especialmente para la geolocalización de pacientes.
Pelatihan Bantuan Hidup Dasar Pada Security Guard Universitas Kristen Satya Wacana
Authors: De Fretes Fiane , Natawirarindry Catherine , Evarayanti Rosiana , Desi Desi
Published: January 2025

Analisis Badan Pusat Statistik Salatiga (BPS) pada dua tahun terakhir menunjukan adanya peningkatan angka kejadian kecelakaan lalu lintas sebesar 6%. Berdasarkan masalah ini, maka kompetensi Bantuan Hidup Dasar (BHD), tidak hanya perlu dikuasai oleh tenaga kesehatan saja, tapi perlu adanya keterlibatan orang awam terlatih yang sewaktu-waktu dapat menghadapi kondisi kegawatdaruratan, sehingga dapat memberikan pertolongan dan mempertahankan kehidupan korban, dalam hal ini para satpam. Tujuan kegiatan ini adalah pelatihan P3K/BHD kepada security guard UKSW. Metode pelatihan terdiri dari ceramah dan simulasi yang dilakukan terhadap 41 orang security guard UKSW. Pre dan Post Test juga diberikan dalam bentuk google form untuk mengukur peningkatan kemampuan kognitif pada responden dan dianalisis menggunakan T-Test. Kepuasan para responden juga diukur menggunakan kuesioner g-form. Hasil pengabdian masyarkat menunjukan adanya peningkatan kognitif setelah intervensi (Hasil T-Test 0,000 (p<0.0001) dan kepuasan terhadap kegiatan sebesar 76.67%. Kesiapan responden dan kebutuhan terhadap kompetensi BHD turut mendukung peningkatan kognitif dan kepuasan responden terhadap pelatihan ini. Oleh karena itu, perlu dilakukan Agar para satpam dapat menjaga kualitas kompetensi, maka perlu dilakukan pelatihan yang yang sama minimal 1x/tahun dan menambahkan pelatihan lain misalnya mitigasi bencana
Mastery Issues and Teaching Approaches for the Electrical Technology Certificate Programme at Community Colleges on the Topic of Measuring Instruments
Authors: Tee Tze Kiong , Ramlan Aryati , Azman Mohomed Nor Azhari Azman , Bagus Nur Rahma Putra Andika , Sukardi Sukardi , Risfendra Risfendra , Abd Hamid Ruhiana Idayu
Published: January 2025

The teaching approach has a significant impact on a student's ability to master a course. The purpose of this study is to identify the level of competence and explore the teaching approaches used by community college lecturers for the Electrical Technology Certificate Programme for the topic of Measuring Instruments. This study employs a qualitative approach with an explanatory research design that includes interview data gathering procedures with eight lecturers who have taught electrical courses before. According to the findings, students' comprehension of the issue of measurement instruments is still at a modest level. While students must learn the concept of measuring instruments, it is a fundamental knowledge. Teaching and learning approach must be adjusted and improved to improve students’ understanding. According to the data, the lecturers' teaching methods are also traditional. Lecturers are enthusiastic about implementing improvements to the teaching and learning process, such as the use of engaging learning modules to increase students' understanding and skills, particularly in the area of measurement instruments.
Pelatihan Budidaya Tanaman Obat di Kelompok Tani Sumber Rejeki, Desa Peniron, Kecamatan Pejagoan, Kabupaten Kebumen
Authors: Fatmawati Nurlaila , Rahmawati Aulia , Nugroho Rahmat Joko
Published: January 2025

Program pengabdian kepada masyarakat yang dimuat dalam tulisan ini bertujuan untuk mengedukasi masyarakat mengenai pentingnya tanaman obat, perkembangannya, prospek dan cara melakukan budidayanya pada lahan yang dimiliki oleh masyarakat. Program pengabdian masyarakat ini dilaksanakan pada 31 Juli hingga 14 Agustus 2023. Program ini melibatkan 30 anggota Kelompok Tani Sumber Rejeki yang ada di Desa Peniron, Kecamatan Pejagoan, Kabupaten Kebumen. Kegiatan pengabdian ini dibantu oleh tim Program Penguatan Kapasitas Organisasi Mahasiswa (PPK Ormawa) Agroteknologi UMNU Kebumen. Edukasi dilakukan dengan melakukan sosialisasi dan pelatihan budidaya tanaman obat di kelompok tani. Kegiatan pelatihan ini disampaikan informasi tentang 1) perkembangan tanaman obat di Indonesia, 2) prospek tanaman obat, 3) budidaya tanaman obat, dan 4) pengenalan varietas unggul tanaman obat. Setelah sesi sosialisasi dilakukan diskusi dan tanya jawab dari materi yang disampaikan kemudian dilanjutkan praktik budidaya tanaman obat. Antusias anggota kelompok tani dapat dilihat dari banyaknya pertanyaan pada sesi diskusi dan keikutsertaan peserta dalam melakukan pelatihan budidaya tanaman obat. Hasil pelatihan yang dirasakan oleh masyakarat yaitu 1) lahan yang dimiliki ketua kelompok tani telah tertanam tanaman obat secara optimal untuk peningkatan ekonomi kelompok tani, 2) kelompok tani memiliki pengetahuan baru terkait olah tanah dan varietas tanaman obat, dan 3) peningkatan kesadaran pemerintah desa dan kelompok tani akan kelestarian lingkungan dengan melakukan budidaya tanaman obat.
Analysis of Life Skills of High School Students who Participate in Extracurricular Sports (Study Based on Regional Demographics)
Authors: Rajab Muhammad Oktapian Nur , Gumilar Agus , Hambali Burhan
Published: January 2025

The purpose of this study was to analyze the level of life skills of high school students in rural areas who take part in extracurricular sports. The method used in this research is a quantitative descriptive method. The participants in this study were high school students in rural areas who participated in extracurricular activities. A total of 240 students were used as participants, consisting of 87 male students and 153 female students. The research instrument used was the Life Skills Assessment Scale (LSAS) developed by Pearson and Kennedy. The results showed that the level of life skills of high school students in rural areas was in a high level category, both those who participated in sports and non-sports extracurricular activities. Meanwhile, the Sig. (2-Tailed) on the Independent Samples Mann-Whitney U test analysis is 0.477. This finding indicates that there is no significant difference in the life skills of high school students who participate in extracurricular sports compared to those who participate in non-sport extracurricular activities (Sig. (2-Tailed) 0.005)
The Role of Government in Awarding Outstanding Student Athletes in West Bandung Regency
Authors: Rudiawati Winda , Nuryadi Nuryadi , Gumilar Agus
Published: January 2025

Awards are a form of appreciation for the efforts and achievements of student athletes who have brought pride to their region. Sports are one of the benchmarks of success, both for athletes, regions, and countries. In addition, sports also reflect good cooperation between the government and the community. Athletes' achievements do not happen by chance but require full attention and support from the government. A survey was conducted on sports administrators in the West Bandung Regency area with 45 respondents. Based on the analysis, policy implementation and budget management have a significant influence on the expected success. Awards have been proven to motivate athletes, especially if given consistently and on time. Although the government has tried to improve the quality of awards every year, there are still many things that need to be improved, especially related to adequate support and training
Nurturing Learning and Engagement Through Student Perceptions of Project-Based Learning
Authors: Ahmed Atta Abdalwahid
Published: January 2025

Project-Based Learning (PBL) refers to an instructional approach where students engage in exploring and solving real-world, complex problems over an extended period. The present study aims to explore the impacts of project-based learning in nurturing student learning and engagement in Kurdish EFL high school context. The design of the study followed a descriptive approach using quantitative methods. The population of the study comprised 364 high school learners from grades 10, 11, and 12 in one of the public schools in Sulaymaniyah, Kurdistan region of Iraq. The data was analyzed through the Statistical Package of Social Sciences (SPSS). The independent sample t-test was employed to investigate the differences between male and female participants. Furthermore, ANOVA one-way was utilized to assess the variations among academic levels. The findings suggested that gender does not have a direct impact on experiences and attitudes of the learners towards PBL. Conversely, there is a significant difference between male and female in students’ perceptions in perceived benefits of PBL. Regarding the academic levels, there is a significant difference between grade 10 and 11 and grade 12 in both categories. These outcomes offer insights to teachers and educators to implement project-based learning in educational practices in various teaching environments.
Exploring the Relationship Between Job Satisfaction and Employee Engagement in Dynamic Work Environments in Era Industry 4.0
Authors: Marlita Devi
Published: January 2025

Employee engagement is a crucial problem within the Company, and it is still important to research because it has great potential for employees to deliver their work results. The research method used is descriptive quantitative, with questionnaires distributed to respondents as the basis for data processing. Based on the results of data processing using smart PLS, all independent variables and the dependent variable have a positive and significant relationship. This research produces findings that employee engagement can be created well if it is supported by several Leadership Styles, Organizational Culture, Employee Benefits, and Job Satisfaction variables. Employee engagement is a critical factor in ensuring organizational success, particularly in the fast-paced and competitive logistics industry. This study aims to optimize the employee engagement program within a logistics company by identifying key drivers and implementing targeted strategies. Using a mixed-method approach, data were collected through surveys, interviews, and company performance metrics to analyze the relationship between engagement levels and organizational outcomes. The findings reveal that clear communication, recognition, and opportunities for professional development are the primary factors influencing employee engagement. Based on these insights, a tailored engagement program was developed and tested, resulting in improved employee satisfaction, productivity, and retention rates. This study provides practical recommendations for logistics companies seeking to enhance employee engagement and highlights the importance of aligning organizational goals with employee needs to foster a sustainable and motivated workforce.
The Impact of Risk-Based Internal Audit Approach on Improving Risk Management Processes: A Field Study in Yemeni Islamic Banks (Aden)
Authors: Attaf Wala Farid , Bensbahou Aziz
Published: January 2025

This study explores the impact of the Risk-Based Internal Audit approach on improving risk management processes in Yemeni Islamic banks in Aden. The study focuses on four core RBIA functions: early identification, risk assessment, control evaluation, and monitoring and reporting. Data from eight banks were analyzed using SPSS, linear regression, and ANOVA. In light of the study's results, there is a statistically significant impact of the risk-based internal audit approach in improving risk management processes in Islamic banks operating in Aden by 51.3%.  According to the results, the control evaluation function ranked first in influencing the improvement of risk management processes with a rate of 45.2%, followed by risk assessment at 39.9%, and early detection at 32.2%. The study suggests that the management of Yemeni Islamic banks should take into account the recommendations and reports submitted by the Internal Audit Department regarding risk management activities and processes and proposals for improvement, in addition to the need for the management of Yemeni Islamic banks to support and develop communication systems between them and the Internal Audit Department to facilitate the exchange of necessary information on time, to support the monitoring and reporting function, which had the lowest impact rate of 24.3%.
Comparative study of the grain yield and morpho-physiological behavior of three varieties of hard-wheat (Triticum durum Desf.) under saline stress
Authors: Hoggas Farida , Khammar Hichem , Kribaa Mohammed , Ababsa Nawal , Boudjabi Sonia , Chaffai Amin , Bouchema Nadhir
Published: January 2025

This study examined the impact of salinity on the physiology and productivity of three durum wheat varieties (M.B.B., Waha, and Boussellam) under different salt concentrations (0 mmol, 4 mmol, and 8 mmol). A factorial design was applied in a pot experiment with soil capacity of approximately 7 kg. Key physiological and productivity parameters, such as leaf area, plant height, number of plants, and grain yield, were assessed. The results showed that the highest salinity level (8 mmol) had a significant negative effect on leaf area, plant height, number of plants, number of ears, and grains per ear. At a salinity of 4 mmol, canopy temperature, number of tillers, biomass, thousand grain weight (TGW), and overall yield were affected. Among the varieties tested, M.B.B. and Boussellam demonstrated greater tolerance to salinity compared to Waha. These findings highlight the differential response of durum wheat varieties to salinity stress, suggesting that M.B.B. and Boussellam may be more resilient options for saline environments.
Hybrid kinetic-fluid simulation of capacitive discharges in H2/Ar Plasma: A 2D analytical approach
Authors: Mostefaoui Mohamed , Taleb Rachid
Published: January 2025

This article presents a systematic characterization of discharges in a capacitively coupled hydrogen/argon mixture using a low-pressure cylindrical configuration with parallel plates. The study uses numerical simulation to explore the behavior of a mixture containing 20% argon and 80% hydrogen under different plasma parameters. The research emphasizes the efficiency of hydrogen production through reactions with the walls, as opposed to electron impact dissociation. It identifies that at 20% argon, the dominant ions are H3+ and ArH+, which are produced through specific reactions within the discharge. The study specifically investigates the plasma parameters and their impact on the hydrogen/argon mixture, providing detailed insights into the discharge behavior and dominant reactions. The focus is on understanding the mechanisms of hydrogen production and ion formation in the plasma environment.
Ferramentas de educação em saúde aplicada na adesão e permanência do aleitamento materno (AM): uma revisão da literatura
Authors: Pikhardt Tamila Cunha , Alencar Mariana Sofia Ferreira , Costa Laressa Ferreira da , Campos Claudia Nayana de Sousa , Rolindo Joicy Mara Rezende , Matos Marcos André de , Reis Meillyne Alves dos
Published: January 2025

Objetivo: Analisar o que há descrito na literatura científica, frente às ferramentas de educação em saúde, que são aplicadas, junto às gestantes, parturientes e / ou puérperas para favorecer a adesão e permanência do aleitamento materno (AME). Material e método:  Trata-se de um de revisão integrativa da literatura (RIL) realizada de acordo com etapas metodológicas na prática baseada em evidências (PBE) proposta na literatura e recomendações do Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) a partir de 2017 até 30 de junho de 2024 tendo por marco inicial a portaria ministerial nº 2.436/2017. A busca ocorreu no período de setembro a outubro de 2024, nas bases de dados: Public/PublishMedline (PUBMED), Base de Dados de Enfermagem (BDENF), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (SciELO) e Web of Science, via Portal de Periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) por meio do acesso à Comunidade Acadêmica Federada (CAFe) por todos os pesquisadores. Resultados: Para a redação final foram utilizados 18 artigos. A partir da análise crítica e detalhada dos artigos, emergiram as seguintes categorias: Categoria A - Aleitamento Materno (AM): (Des) Conhecimento e práticas seguras para a adesão e permanência e Categoria B - Tecnologias do cuidado em saúde centrada no autocuidado puerperal. Considerações Finais: As tecnologias do cuidado em saúde devem ser utilizadas pelos profissionais de saúde junto às mulheres e sua rede de apoio, como ferramentas para a manutenção e adesão ao AM durante todo o manejo clínico da assistência. Sugere-se a capacitação dos profissionais de saúde para o manuseio adequado das ferramentas que devem auxiliar no processo e jamais substituir o relacionamento humano fletido em acolhimento individualizado e humanizado.
Crescimento de mudas de mamoeiro ‘Aliança’ em diferentes lotações por tubete
Authors: Santos Thiago Vieira dos , Bonelá Édlen dos Santos , Grobério Rafaela Barreto Cazaroto , Carrafa Militino Paiva , Czepak Marcio Paulo , Fernandes Adriano Alves , Pereira Felipe Batista , Schmildt Edilson Romais
Published: January 2025

O cultivo de mudas de qualidade é essencial para o sucesso da produção de mamoeiros, especialmente em cultivares como ‘Aliança’, que possuem grande relevância comercial. O objetivo deste trabalho foi avaliar o crescimento de mudas de mamoeiro ‘Aliança’ submetidas a diferentes densidades de plantio por tubete. As mudas foram produzidas em um viveiro comercial no município de Sooretama, Espírito Santo, utilizando tubetes com capacidade de 50 cm³ e o substrato Bioplant®. A semeadura ocorreu em 14 de junho de 2023, com três sementes por tubete. Não houve desbaste inicial, e, 12 dias após a emergência, os tubetes foram organizados em três tratamentos, conforme o número de mudas por tubete: uma, duas ou três. As avaliações das mudas, realizadas no estágio de expedição, ocorreram em 20 de julho de 2023. O experimento foi conduzido com três tratamentos e 70 repetições, totalizando 70, 140 e 210 mudas por tratamento, respectivamente. Foram analisadas a altura das mudas (cm), diâmetro do coleto (mm), número de folhas (un), área foliar (cm²), massa seca da raiz (mg) e massa seca da parte aérea (mg). Com base nesses dados, foi calculado o Índice de Qualidade de Dickson. Os resultados foram submetidos ao teste não paramétrico de Kruskal-Wallis (p < 0,05), seguido pelo teste de Dunn (p < 0,05), utilizando o software R. O manejo com uma única muda por tubete proporcionou os melhores resultados em todas as características avaliadas, indicando a obtenção de mudas mais vigorosas e adequadas para expedição.
A presença do pensamento filosófico de Santo Agostinho na obra “O Silmarillion” de J. R. R. Tolkien
Authors: Fernandes Mateus de Melo , Fernandes Marcela de Melo
Published: January 2025

O Bem e o Mal, o processo originário do universo e a criação de todas as coisas, o embate entre a Natureza e o Pecado Original, o Livre-Arbítrio sempre ocuparam a mente humana. Em Tolkien estes impasses ganham vida em seu legendarium e se entrelaçam ao pensamento de Santo Agostinho. Haveria então uma estreita ligação com o pensamento de Santo Agostinho e a obra “O Silmarillion”? Deste modo, em uma revisão bibliográfica de caráter exploratória e descritiva, com uma abordagem qualitativa, objetivamos analisar e interpretar a relação entre as ideias filosóficas de Agostinho e os elementos narrativos presentes no livro “O Simarillion”, de J. R. R. Tolkien. Pode-se perceber uma estreita aproximação dos escritos de Tolkien aos conceitos propostos no período medieval pelo filósofo cristão e bispo católico Agostinho de Hipona. Concluímos assim, após análise, que “O Silmarillion”, não obstante a sua natureza mitológica na construção da ficção, possui sua base fundante no pensamento filosófico de Santo Agostinho, estando ainda, fortemente alicerçado nos valores e virtudes cristãs da fortaleza, justiça, temperança, prudência, nos oferecendo ainda uma profunda reflexão sobre a condição humana, a liberdade e a relação com o divino.
Análise de série temporal da insolação incidente em Guarapuava, Paraná, região Sul do Brasil nas diferentes fases ENOS
Authors: Moreschi Maria Eduarda Guchineski , Jadoski Sidinei Osmar , Vier Caroline Rack , Rocha Joyceara , Bueno Janaina Cosmedamiana Metinoski , Gusmão Matheus Brandani , Jadoski Arthur Stasiak , Muzzolon Geovane
Published: January 2025

Embora fotoperíodo e insolação estejam diretamente relacionados, o primeiro é específico para dado dia do ano e latitude, e a insolação diária pode ser influenciada pelo clima regional, através da cobertura de nuvens. O estudo foi fundamentado em uma série temporal de dados climáticos referentes ao período 1976 a 2022, com o objetivo de caracterizar a variação da insolação ao longo do ano, e analisar a influência das fases Enos na razão de insolação para a microrregião de Guarapuava, localizada no Centro-Sul do estado do Paraná, região Sul do Brasil. As informações foram agrupadas e analisadas considerando a ocorrência das fases Enos — La Niña, El Niño e de Neutralidade. Os resultados obtidos indicam que a insolação média anual é de 6,35 horas, com variações entre valores máximos e mínimos, que vão de 4,9 horas em maio a 6,8 horas em agosto durante o período de El Niño, 5,8 horas em junho e 7,4 horas em novembro para a fase de La Niña, e 5,9 horas em maio e junho e 7,1 horas em novembro na fase de Neutralidade atmosférica. A variabilidade da insolação foi considerada baixa, com os coeficientes de variação mensais apresentando valores próximos ou inferiores a 15% para os diferentes meses do ano e para as fases do ENOS.
Subsídios para a interface neurociências e ensino (artigo de opinião)
Authors: Guilherme José Francisco Nunes , Martins Carla Alexandra Ramalho de Sena
Published: January 2025

O objetivo deste artigo, potenciar o ato pedagógico através das neurociências destaca a importância do diálogo entre neurociências e educação para melhorar o processo de ensino/aprendizagem. O artigo aborda a aprendizagem como uma modificação do comportamento que pode ser cognitiva, afetiva, motora ou social. Discute diferentes teorias de aprendizagem, como as behavioristas e cognitivistas, e enfatiza a importância da histérese do sistema, que mostra como o cérebro muda com a experiência. As emoções são destacadas como fundamentais para a aprendizagem, influenciando a atenção e a memória. O artigo explica como diferentes sistemas cerebrais produzem emoções e como estas podem ser reconhecidas e induzidas. Para fortalecer a interface entre neurociências e ensino, sugere-se:  eliminar neuromitos; incluir neurociências na formação de professores; e, criar infraestruturas que facilitem a colaboração entre laboratórios, universidades e escola. A conclusão reforça a necessidade de desmistificar o funcionamento do cérebro para melhorar o ensino, defendendo que um maior conhecimento das neurociências pode contribuir para práticas educativas mais eficazes e humanizadas.
The Aim of Education: Insights from the Movie "Seediq Bale"
Authors: Qiu Jing
Published: January 2025

The education of the Seediq people embodies the pursuit of multicultural values, such as the reverence for the unity of man and nature, the spirit of bravery, and collectivism. In contrast, Japanese colonial education aimed at "Japanimation," disregarding the subjectivity of indigenous people and eliminating cultural diversity, which ultimately led to the resistance of the Seediq people. This enlightens us that the purpose of education should be to awaken individual consciousness, respect students' individuality, stimulate national confidence, cultivate cultural awareness, maintain cultural diversity, promote multicultural exchanges, adhere to a people-oriented approach, and foster students' all-round development. Only by practicing these concepts can education become an undertaking of cultural inheritance and human liberation, contributing wisdom and strength to national rejuvenation and human progress.
Premessa
Authors: Modenesi Marco
Published: January 2025

Premessa al volume 76, numero 1-2, 2023.
Analysing Classroom Management Strategies As the Main Pillar of Successful Student Learning Achievement
Authors: Amalia Tiara , Na’imah Na’imah , Azizah Yulia Lutfiyani , Hidayatussa’adah Hidayatussa’adah , Sadad Roihan
Published: January 2025

Classroom management plays a crucial role in creating a learning environment that supports student learning outcomes. The research was conducted qualitatively through a documentation study, collecting previous research findings to analyze the pillars of classroom management that influence student learning. Data processing involved searching, filtering, assessing feasibility, and analyzing article content. The results of the study show: First, an effective learning community requires teachers to design learning spaces by considering student diversity, processes, and class structure to encourage participation, strengthen interaction, and improve learning outcomes. Second, managing teacher-student interactions creates a conducive atmosphere that supports the achievement of learning goals, character development, and positive relationships, which increases motivation and learning outcomes. Third, the use of varied teaching methods can enhance critical thinking skills, reduce boredom, and increase student engagement. Fourth, a comfortable and organized classroom atmosphere improves concentration, understanding, and retention of information. In conclusion, good classroom management can enhance student learning outcomes.
Musik Moderasi: Konsep Bermusik dalam Keberagaman di Kota Kupang, Nusa Tenggara Timur
Authors: Huka Relin Yosi , Tabun Andrean
Published: January 2025

In general, music can live in the community of human life both culturally, ethnically and religiously and develop according to the needs of the culture, ethnicity and religion itself. In a more general context, it can also be interpreted that music can also be a unifying tool in uniting various differences of opinion. Moderation is the concept of adjusting an atmosphere in relation to providing an understanding of equality and balance in interpreting the basics of a good life in pluralism. Pluralism in this context is associated with the growing religious diversity in the city of Kupang, East Nusa Tenggara. Music can unite and become a means of uniting various religions in responding to national contexts that are different but still one. This research takes the concept of moderation in music as a means to provide space for expression in the context of pluralism.
Demand-Oriented Social Work Practice Logic
Authors: Qi Yufan , Pan Siyu
Published: January 2025

The advancement and development of social work in China rely heavily on government policy support and resource investment. Currently, social work services are primarily promoted through government-purchased services, which essentially cater to the needs of grassroots government innovation in social governance. This has gradually led to a top-down, one-way supply of social work services, where residents passively receive services. This model often overlooks the actual needs of service recipients, resulting in issues such as repeated services for the same recipients, a focus on process rather than outcomes, superficial intervention, and ineffective services, thus wasting resources and diminishing the professionalism of social work. Technological innovations, such as the internet and artificial intelligence, have deeply integrated into people's behavioral patterns, leading to increasingly diverse, personalized, and complex demands from residents. These heightened demands place greater pressure on social work services while the accumulation of substantial livelihood data provides an opportunity for the development of social work. Based on recent practical explorations and abundant case studies concerning livelihood data, this paper explores the use of such data to transform service logic, with residents' needs as the starting point for all services. It proposes a demand-oriented approach at each stage of social work services, including demand perception, identification, provision, and evaluation, to establish a demand-oriented social work practice logic.
The effect of ginsenoside Rg3 combined with doxorubicin on the proliferation of MHCC97-L liver cancer cells
Authors: Zhu Hanyu
Published: January 2025

Purpose: MHCC97-L liver cancer cells, as one of the common liver cancer cells, have 40% metastasis rate of lung cancer. As a commonly used and widely used drug for the treatment of various cancers on the market, doxorubicin has also shown significant effects in treating MHCC97-L cells in previous studies. Meanwhile, research has also shown that ginsenoside Rg3 can play a significant role in the treatment of MHCC97-L liver cancer cells. This study explores the therapeutic effect of the combination of ginsenoside Rg3 and doxorubicin on MHCC97-L liver cancer cells, in both vitro and vivo. Methods: The experiment will use MHCC97-L human liver cancer cell and xenograft mouse model. The cell proliferation is measured by using the CCK-8 detection method and the tumor inhibition rate of the drug in vivo experiments can be calculated formula. Possible results: There are 3 most possible results: (1)The combination of doxorubicin and ginsenoside Rg3 has stronger inhibitory effect than doxorubicin only on MHCC97-L cells, both in vitro and in vivo; (2) The combination of doxorubicin and ginsenoside Rg3 has a strong inhibitory effect in vitro experiments, but the effect is not significant in vivo experiments; (3) The combination of doxorubicin and ginsenoside Rg3 has similar inhibitory effect than doxorubicin only on MHCC97-L cells, both in vitro and in vivo. Conclusion: Our research results will provide important information for the clinical treatment of chemotherapy for lung cancer. Future research should focus on improving drug interactions in vivo and drug metabolism in vivo.
The Development Process and Characteristics of Antibodies in Antibody-drug Conjugate
Authors: Liang Zeming
Published: January 2025

More than 100 years ago, Paul Ehrlich, the father of immunology, first proposed the concept of magic bullets, i.e., the concept of selectively delivering toxic drugs to target cells while avoiding damage to normal cells in the human body. ADCs, as a new type of anticancer drug, are formed by coupling small molecule cytotoxins with monoclonal antibody molecules through linker molecules. As a new type of anticancer drug, ADC couples a small molecule cytotoxin with a monoclonal antibody molecule through a linker molecule, and the drug formed by the combination is targeted and lethal, leading the new era of targeted cancer therapy. In this review, the current development and outlook of ADCs is comprehensively reviewed, ADCs and ongoing R&D pipelines in the global and Chinese markets are analyzed,Various ADC platforms and technologies pertinent to distinct pharmaceutical and biotech firms are emphasized, alongside an exploration of emerging technologies, potential advancements for next-generation ADCs, and avenues for clinical research.
Glucagon-Like Peptide-1 Receptor Agonists' Effect on Polycystic Ovary Syndrome: A Meta Analysis
Authors: Li Xinrui
Published: January 2025

Glucagon-Like Peptide-1 Receptor Agonist (GLP-1) has caught emerging attention in the medical and scientific world as a cure for many obesities, insulin resistance, and diabetically related illnesses [1]. Over the past years, there are projections and few experiment made upon GLP-1s effect on Polycystic ovary syndrome (PCOS), a hormonal imbalance that affects a woman's ovaries and doesnt have a cure now. This meta-analysis aims to evaluate the effect of GLP-1 RAs on PCOS by reviewing and synthesizing data from randomized controlled trials (RCTs) and clinical trials. We analyzed 14 studies with 669 participants published between 2008 and 2023 across four countries. A random-effects model was used to compare the standardized mean difference (SMD) in body mass index (BMI) and other clinical parameters between treatment and control groups. Our outcome showed no significant reduction in BMI with GLP-1 RAs compared to placebo in PCOS patients (SMD -3.13, 95% CI: -6.44 to 0.17), with high heterogeneity (I = 96%). Secondary outcomes yields that no significant differences were found in weight reduction, HOMA-IR scores, or hormone levels (testosterone, cholesterol, DHEA) when comparing GLP-1 RAs with metformin (SMD -0.10, 95% CI: -0.48 to 0.28). These findings suggest that GLP-1 RAs do not significantly improve PCOS symptoms. The substantial heterogeneity across studies highlights the need for further research with larger, more standardized sample sizes.
Use ER stress inhibitor BiP Inducer X in ZIKV-infected brain organoid to see if reducing ER stress through ATF6 pathway can alleviate pathological feature of Alzheimers disease
Authors: Zhang Yuqi
Published: January 2025

Alzheimers disease (AD), a gradually worsening neurodegenerative disorder, typically affects the elderly people. Widely acknowledged as the primary cause of AD is the accumulation of -amyloid (A) outside cells and the formation of neurofibrillary tangles inside cells. Presently, there exists no efficacious therapy to slow down the emergence and progression of AD and many scientists are finding ways to cure AD through different aspects. There are some experiments have indicated that ER stress contributes to the onset and development of AD. Therefore, some scientists are having experiments on AD by inhibit ER stress using different inhibitors through different pathways. Zika virus (ZIKV) have been proved to be able to increase a accumulation and p-tau level in AD brain organoid. After ZIKV infection, phenotypes linked to AD in brain organoids saw an increase due to stress in the endoplasmic reticulum (ER) and the unfolded protein response (UPR).The BiP Inducer X(BIX)is used in this experiment to investigate the effect of inhibitor on AD via activating transcription factor 6(ATF6)pathway in ZIKV-infected brain organoid models. The A accumulation and p-tau level is recorded by immunostaining to form image. This paper only provides theoretical experiment design and possible result about whether the inhibition on ER stress through ATF6 pathway would reduce AD features, which need further research in the pathology of AD.
Effects of Reducing Synaptic Plasticity on Resilience to Depression and Anxiety in ASCL1 Mouse Model
Authors: Gao Xin
Published: January 2025

Major depression is correlated with neuroplasticity, including synaptic plasticity. This research aims to determine the impacts of altering synaptic plasticity in adult-born hippocampal neurons on ASCL1 mices resilience to depression and anxiety and hypothesizes that reducing synaptic plasticity decreases resilience to major depressive disorder. For this purpose, this ASCL1 mouse model is used to edit genes controlling the formation of long-term potentiation (LTP) by N-Methyl-D-Aspartate Receptor (NMDAR). Relative studies are discussed and analyzed, giving deeper insights into understanding molecular neural circuits and mechanisms of depression and providing support for novel ideas of depression treatment.
The Mechanism of RNA-Dependent Intergenerational Inheritance and Factors Affecting Its Transition to Transgenerational Inheritance
Authors: Lin Shirui
Published: January 2025

Some studies have revealed the effects of environmental arsenic exposure on the learning and memory ability of male rats and its epigenetic mechanism, and found that arsenic exposure led to the downregulation of cognitive-related gene expression, the change of histone modification, and then caused neurotoxicity, and the paternity exposure caused cross-generation learning and memory impairment in F2 generation male rats. In fact, in addition to the harsh environment, providing a favorable environment for mice can also show the phenomenon of cross-generational inheritance in their offspringVarious studies indicate that the environmental enrichment greatly enhance long-term memory and cognitive levels. Environmental enrichment, which includes a rich social and physical environment, enhances long-term memory and cognitive function in mice. For example, the offspring of male mice that received environmental enrichment and emotional training show substantial gains in cognitive ability and long-term potentiation (LTP), even without similar training themselves. This suggests that the impact of environmental enrichment can be inherited genetically to the subsequent generation. It is thought that the genetic effect of miR 212/ 132 in sperm is mediated by the former. While prior studies emphasize the significance of miR 212/132, the current study focuses primarily on the available literature and has some limitations. Thus, this proposal will try to expand the knowledge of factors connected with memory inheritance, especially the factors associated with the impact of environmental effects in enrichment, and thus, understand the actual complexity of the aforementioned genetic processes and the modulating influence of environmental stimuli on the genetic patterns.
Optimization of biohydrogen production by modifying metabolic pathways in Clostridium Thermocellum
Authors: Chen Zilong , Wang Kaden , Li Fengyi
Published: January 2025

The ever-escalating energy crisis of disruptions in the supply of fossil fuels suggests the need for alternative means with sustainable energy sources. Of these, biohydrogen stands out as promising because it is clean and efficient. Our research aims to provide strategies for fine-tuning the biohydrogen production process using the dark fermentation pathway of Clostridium. Thermocellum since it efficiently degrades cellulose under anaerobic conditions and has high-temperature tolerance, improving hydrogen yield. Sugarcane bagasse enforces this integration by providing abundant resources at little cost, which can support circular economies. However, such problems as ethanol toxicity to C. Thermocellum require genetic modifications to enhance production efficiency. The plasmid design overexpresses NADH-dependent [FeFe] hydrogenase, knocks out ethanol production pathways, and hence maximizes biohydrogen output. The design of the plasmid mainly uses Golden gate assembly and homologous recombination to achieve gene overexpression and deletion, and restriction sites were designed for virtual digestion in plasmid verification.