bluuebunny/crossref_metadata_2025 huggingface dataset:
Environmentally Relevant Concentrations of Triphenyl Phosphate (TPhP) Impact Development in Zebrafish
Authors: Schmandt Benjamin , Diduff Mfon , Smart Gabrielle , Williams Larissa M.
Published: May 2024

A common flame-retardant and plasticizer, triphenyl phosphate (TPhP) is an aryl phosphate ester found in many aquatic environments at nM concentrations. Yet, most studies interrogating its toxicity have used µM concentrations. In this study, we used the model organism zebrafish (Danio rerio) to uncover the developmental impact of nM exposures to TPhP at the phenotypic and molecular levels. At concentrations of 1.5–15 nM (0.5 µg/L–5 µg/L), chronically dosed 5dpf larvae were shorter in length and had pericardial edema phenotypes that had been previously reported for exposures in the µM range. Cardiotoxicity was observed but did not present as cardiac looping defects as previously reported for µM concentrations. The RXR pathway does not seem to be involved at nM concentrations, but the tbx5a transcription factor cascade including natriuretic peptides (nppa and nppb) and bone morphogenetic protein 4 (bmp4) were dysregulated and could be contributing to the cardiac phenotypes. We also demonstrate that TPhP is a weak pro-oxidant, as it increases the oxidative stress response within hours of exposure. Overall, our data indicate that TPhP can affect animal development at environmentally relevant concentrations and its mode of action involves multiple pathways.
Isolation and Identification of Morganella morganii from Rhesus Monkey (Macaca mulatta) in China
Authors: Li Heling , Chen Zhigang , Ning Qing , Zong Faliang , Wang Hong
Published: May 2024

A bacterium was isolated and identified from the secretion of a rhesus monkey with endometritis. The morphological results showed that the strain exhibited round, convex, gray-white colonies with smooth surfaces and diameters ranging from 1 to 2 mm when cultured on Columbia blood agar at 37 °C for 24 h; on salmonella–shigella agar (S.S.) at 37 °C for 24 h, the colonies appeared round, flat, and translucent. Gram staining showed negative results with blunt ends and non-spore-forming characteristics. Molecular biology results showed that the 16S rRNA sequence of the strain revealed over 96.9% similarity with published sequences of M. morganii from different sources in the NCBI GenBank database. Morphological and molecular biology analysis confirmed that the strain (RM2023) isolated from cervical secretions of rhesus monkey was M. morganii. Drug sensitivity testing demonstrated that the isolated strain (RM2023) was sensitive to ceftriaxone, amikacin, gentamicin, cefazolin, cefuroxime, ceftazidime, levofloxacin, cotrimoxazole, norfloxacin, and tetracycline; moderately sensitive to ampicillin; and resistant to penicillin, vancomycin, ciprofloxacin, and clindamycin. The research findings provide valuable insights for disease prevention in rhesus monkeys and contribute to molecular epidemiological studies.
Synergistic Removal of Nitrogen and Phosphorus in Constructed Wetlands Enhanced by Sponge Iron
Authors: Shen Yiwei , Hu Meijia , Xu Yishen , Tao Mengni , Guan Lin , Kong Yu , Cao Shiwei , Jing Zhaoqian
Published: May 2024

Insufficient denitrification and limited phosphorus uptake hinder nitrogen and phosphorus removal in constructed wetlands (CWs). Sponge iron is a promising material for the removal of phosphorus and nitrogen because of its strong reducing power, high electronegativity, and inexpensive cost. The influence of factors including initial solution pH, dosage, and the Fe/C ratio was investigated. A vertical flow CW with sponge iron (CW-I) was established, and a traditional gravel bed (CW-G) was used as a control group. The kinetic analysis demonstrated that for both nitrogen and phosphorus, pseudo-second-order kinetics were superior. The theoretical adsorption capacities of sponge iron for nitrate (NO3−-N) and phosphate (PO43−-P) were 1294.5 mg/kg and 583.6 mg/kg, respectively. Under different hydraulic retention times (HRT), CW-I had better total nitrogen (TN) and total phosphorus (TP) removal efficiencies (6.08–15.18% and 5.00–20.67%, respectively) than CW-G. The enhancing effect of sponge iron on nitrogen and phosphorus removal was best when HRT was 48 h. The increase in HRT improved not only the nitrogen and phosphorus removal effects of CWs but also the reduction capacity of iron and the phosphorus removal effect. The main mechanisms of synergistic nitrogen and phosphorus removal were chemical reduction, ion exchange, electrostatic adsorption, and precipitation formation.
Contribution of the prominent Russian hygienist F. G. Krotkov to the development and practical use of military uniforms
Authors:   Researcher, veteran of the sanitary and epidemiological service, Ryazan, Russia, Panin V. F. , Cherednikova V. I. ,   Federal Budgetary Healthcare Institution “Center of Hygiene and Epidemiology in the Ryazan region, Ryazan, Russia
Published: May 2024

The article presents some historical information about the origin and development of the doctrine of clothing in general and military clothing in particular. The data on the conduct of research on the hygienic properties of clothing and shoes by domestic military hygienists are presented. The role of F. G. Krotkov in the development of scientifically based requirements for military uniforms, the relevance of which remains to the present time, is emphasized.
On the role of training specialists in the medical and preventive profile for the bodies and institutions of Rospotrebnadzor of the Far Eastern Federal District on the basis of a unified educational, scientific and industrial complex
Authors:   Pacific State Medical University of the Ministry of Health of the Russian Federation, Vladivostok, Russia, Vershkova T. I. , Sheparev A. A. ,   Pacific State Medical University of the Ministry of Health of the Russian Federation, Vladivostok, Russia, Yanovich V. A. ,   Pacific State Medical University of the Ministry of Health of the Russian Federation, Vladivostok, Russia
Published: May 2024

The article presents the experience of training specialists in the medical and preventive profile for the bodies and institutions of Rospotrebnadzor of the Far Eastern Federal District on the basis of a single educational, scientific and industrial complex, the successful operation of which occurred in the period 1992–2004. A number of government agencies and organizations, universities, research institutes of the Far Eastern Branch of the Russian Academy of Sciences were involved in the work and participation in the complex. Based on the results of joint work, scientific and practical works were published, Health programs were developed for the territories of the Far Eastern region and individual enterprises of the leading branches of the military-industrial complex, shipbuilding, ship repair, instrumentation, light industry, construction industry, chemical industry, transport. All published documents and programs had practical significance, were implemented, and gave invaluable results in improving the health indicators of working contingents.
An attempt at systematizing errors in bronchology practice
Authors:   SBHI SR Samara City Hospital No. 4,FSBEI HE Samara State Medical University of the Ministry of Health of Russia, Shteiner M. L.
Published: May 2024

A systematization of errors in the practice of analyzing bronchopulmonary pathology was carried out. This study analyzes the records of 18,268 patients who underwent a total of 37,264 bronchoscopies (including both initial and subsequent procedures) from 2006 to 2023. The most common errors were identified at various stages: in the decision-making process for conducting bronchoscopy, in the preparation for the procedure, and during the bronchoscopy itself. These common errors are illustrated with clinical examples. The study concludes that eliminating errors in planning, preparation, and the actual performance of bronchoscopy is crucial for minimizing the risk of complications associated with this procedure.
Stopping epistaxis: a step-by-step approach
Authors:   Central City Hospital named after N. A. Semashko, Rostov-on-Don, Russia, Gulyaeva N. N.
Published: May 2024

Spontaneous epistaxis is often encountered in the practice of ENT-specialists. Suc cessful treatment of this group of patients requires adherence to a certain sequence of mea sures, that is a step-by-step approach to stopping nosebleeds. The first step is tampon-free methods, among which electrocoagulation of a bleeding vessel takes a crucial place.
Occupational lung diseases from exposure to industrial fibrogenic aerosols of varying degrees of fibrogenicity: occupational risk assessment, features of immunopathogenesis, prediction
Authors:   FSBEI HE Samara State Medical University of the Ministry of Health of the Russian Federation, Babanov S. A. , Budash D. S. ,   SBHI SR Samara City Polyclinic No. 6, Agarkova A. S. ,   FSBEI HE Samara State Medical University of the Ministry of Health of the Russian Federation, Vostroknutova M. Yu. ,   SBHI SR Samara City Hospital No. 5
Published: May 2024

The purpose of the study is to assess occupational risk and study the characteristics of immunopathogenesis in occupational lung diseases from exposure to industrial aerosols. Material and research methods. The study included 304 people with over 10 years of work experience under conditions of exposure to high concentrations of industrial fi brogenic aerosols (above the permissible concentration), who underwent an in-depth periodic medical examination at the regional center of occupational pathology Samara City Hospital No. 5 with an assessment of the relative risk (RR), its etiologic fraction (EF), and odds ratio (OR) of the development of occupational respiratory diseases. The comparison group included 120 people. To assess the cytokine profile indices in occupational lung diseases (various degrees of severity of dust-induced occupational diseases, silicosis, and pneumoconiosis from exposure to highly dispersed welding aerosols), 161 people with occupational lung diseases and 60 people in the control group were examined. Levels of immunoglobulins A, M, and G in blood serum, hemolytic activity of complement, and the level of myeloperoxidase were determined using standard reactions. Determination of the levels of total IgE, fibronectin, cytokines IL-1α, IL-1β, IL-4, IL-8, IFNγ, and TNFα, growth factors FGF-2, VEGF in blood serum was carried out by enzyme -linked immunosorbent assay. Results. The occupational risk of developing dust lung diseases from exposure to various types of fibrogenic industrial aerosols, as well as the features of the course of occupational lung diseases have been determined. The identified features of the immu nological profile allow establishing the features of the occurrence, course, and progres sion of occupational lung diseases and recommending changes to the National List of Occupational Diseases. Conclusions. Determining occupational risk and immunological profile allows not only improving the quality of early diagnosis, but optimizing primary and secondary prevention strategies for this pathology, predicting the course of the disease, and reducing the number of disabling forms.
How to improve the quality of products at an enterprise?
Authors:   ", Degterev M. Yu. ,   Mareven Food Central",   , Russia, Moscow region, Krasnogorsk urban district
Published: May 2024

In the article, the author shared useful tips on how to improve the quality of food products based on the experience of the Mareven Food Central company. To improve the quality of products at an enterprise, it is imperative to comply with all existing technical regulations, instructions and provisions, use advanced technologies and analysis methods, regularly test quality characteristics at all stages of production, always take into account the wishes of consumers, develop quality management, and also pay increased attention to attention to staff training. International and national standards in the field of quality control are indicated, including the FSSC 22000 Food Safety System / HACCP System. The expert named the trends in accordance with which the modern quality control system is developing in the FMCG industry, such as the active growth of awareness of modern consumers about the production process of goods, the widespread use of innovative technologies, accelerating globalization and the extremely high level of competition in the FMCG market. The author also identified the key groups of risks faced by food producers — physical, chemical, microbiological, as well as risks associated with allergic reactions of consumers to products.
Corporate culture аnd team interaction in the context of digitalization of the company
Authors:   direction of training 04/37/01 ", Okhotina M. I. ,   Psychology",   profile ",   Psychology in business and advertising",   Russian Economic University named after G.V. Plekhanov, Russia, Moscow
Published: May 2024

Issues of the relationship between corporate culture and team interaction among employees of an organization in the context of digitalization are considered. An analysis of the concept and function of corporate culture within the framework of team work is presented; focuses on the digital corporate culture of companies
Prospects for use of genetic tagging technology in animal husbandry
Authors:   Federal State Budgetary Institution of Science “Vavilov Institute of General Genetics” Russian Academy of Sciences, Russia, Moscow, Beketov S. V. , Semina M. T. ,   Federal State Budgetary Institution of Science “Vavilov Institute of General Genetics” Russian Academy of Sciences, Russia, Moscow, Mokeev A. S. ,   Institute of Livestock Husbandry of Steppe Regions named after M. F. Ivanov “Askania-Nova” – National Scientifi c Selection and Genetic Center for Sheep Breeding of the National Academy of Agrarian Sciences, Russia, Kherson region, Askania-Nova, Fursa N. N. ,   Institute of Livestock Husbandry of Steppe Regions named after M. F. Ivanov “Askania-Nova” – National Scientifi c Selection and Genetic Center for Sheep Breeding of the National Academy of Agrarian Sciences, Russia, Kherson region, Askania-Nova, Senator A. S. ,   Federal State Budgetary Institution of Science “Main Botanical Garden named after. N. V. Tsitsin” Russian Academy of Sciences, Russia, Moscow, Upelniek V. P. ,   Federal State Budgetary Institution of Science “Main Botanical Garden named after. N. V. Tsitsin” Russian Academy of Sciences, Russia, Moscow, Stolpovsky Yu. A. ,   Federal State Budgetary Institution of Science “Vavilov Institute of General Genetics” Russian Academy of Sciences, Russia, Moscow
Published: May 2024

The efficiency of DNA extraction with using different extraction methods: from the cartilage tissue of the outer ear and the leukocyte fraction of whole blood of cattle, followed by an assessment of the possible prospects for the use of “genetic tagging” technology in animal husbandry has been compared in the work. It was established that according to the results of the research the highest concentration of DNA (146,26±13,180 ng/μl at p < 0,001) was obtained in samples from ear tissues when using the method of precipitation with reagents compared to isolating DNA from the leukocyte fraction of whole blood using highly eff ective methods extraction of genomic deoxyribonucleic acid on magnetic particles (22,80±3,138 ng/μl) and on columns (39,46±8,941 ng/μl). It was found when assessing DNA contamination with polypeptides that despite the fact that when using diff erent extraction methods, the ratio of optical densities at the corresponding absorption wavelengths A260/A280 was close to the optimal ~1,8. The smallest scatter of measurement values was obtained in DNA samples from earmarks tissue 1,89±0,008. In a subsequent comparison of available technologies for taking ear pluck tissue samples used for genetic research (population genetic characterization, genomic analysis, etc.), the FlexoPlusGeno “genetic tagging” system turned out to be the most preferable. In this case, the resulting ear pluck tissue sample is correlated with corresponding ear visual or RFID tags, which creates a “link” of the biomaterial to a specific animal with the ability to track it throughout its life. The technology under consideration is applicable for collecting and storing samples of cartilage tissue obtained by ear plucking from cattle, small ruminants, pigs and deer.
Din Eğitiminin Kültürel Temelleri: 2018 Ortaöğretim Din Kültürü ve Ahlak Bilgisi Dersi Öğretim Programı Bağlamında Bir İnceleme
Authors: Doğru Çetin
Published: May 2024

Öğretim programları, bütün eğitim ve öğretim faaliyetlerinin bir planıdır. Öğretim programlarının planlanma aşamasında Milli Eğitim Temel Kanunu’nda belirtilen genel amaç ve ilkeler dikkate alınmaktadır. Öğretim programları hazırlanırken temel hedefler belirlenmektedir. Bunlar arasında Türk toplumunun millî ve manevi kaynaklarından damıtılarak günümüze ulaş dini, kültürel değerlerin kazandırılmasına ilişkin hedeflere de yer verilmektedir.
Araştırma için doküman incelemesi yöntemi kullanılmıştır. Öte yandan araştırma, durum çalışması deseninde desenlenmiştir. Bu araştırmada veri kaynağı olarak ele alınan 2018 Ortaöğretim DKAB Dersi öğretim programında din, dil, tarih, dünya görüşü, sanat, gelenek ve görenek gibi milli kültür unsurlarının yer alma durumunun tespiti hedeflenmiştir. Araştırmanın veri kaynağından elde edilen veriler, içerik analizi yaklaşımı ile derinlemesine analiz edilmiş ve böylelikle anlamlı çıkarımlar ortaya konulması hedeflenmiştir. Araştırma sonucunda Ortaöğretim DKAB öğretim programında; din, dil, tarih, dünya görüşü, sanat, gelenek ve görenek gibi milli kültür unsurlarına ilişkin birtakım anlam ve ifadelere yer verildiği, bunlarla ilgili bilgi ve konulara değinildiğini söylemek mümkündür.
Studi Komparatif Measurement Smart City Framework (MSCF) untuk Pengukuran Smart City
Authors: Suratno Tri , Edi Saputra  , Ahmad Saparudin
Published: May 2024

Suatu evaluasi dapat dilakukan dengan menggunakan tools yang sering dikenal dengan nama framework. Permasalahan dari Measurement Smart city Framework (MSCF) saat ini adalah belum adanya framework yang dikembangkan secara empiris, sehingga diperlukan tinjauan lebih jauh sebelum digunakan untuk mengukur tingkat keberhasilan suatu smart city. Penelitian ini dilakukan untuk mempermudah pengambil keputusan dalam menentukan MSCF  yang hendak digunakan. Penelitian dilakukan dengan melakukan studi komparasi pada framework SCOTTISH, ESPRESSO, UNECE-IT, BSI, SCPAM, GPCI, dan IESE dengan meninjau indikator, sub indikator, kuesioner pengukuran, dimensi pengukuran, area pengukuran, effort pengukuran, pemetaan pengukuran, fokus responden, serta maturity model dari tiap framework tersebut. Hasil penelitian menunjukkan masing-masing MSCF memiliki karakteristiknya masing-masing. Namun apabila ditinjau dari satu dimensi smart city, maka framework yang direkomendasikan yakni:  smart government dengan SCOTTISH, smart infrastructure dengan IESE, smart living dengan UNECE-ITU, smart economy dengan UNECE-ITU, smart mobility dengan IESE, dan smart environment dengan UNECE-ITU
Peningkatan Proses Monitoring Bimbingan Tugas Akhir Dengan Sistem Informasi Menggunakan Metode Agile Di Perguruan Tinggi
Authors: Hendri
Published: May 2024

Bimbingan Tugas Akhir merupakan proses penting bagi perjalanan akademik mahasiwa, namun sering terjadi masalah dalam pelaksanaan bimbingan tugas akhir seperti pemalsuan tanda tangan pembimbing, pembimbing tugas akhir tidak mengetahui perkembangan kemajuan tugas akhir.Penelitian ini bertujuan untuk mengimplementasi metode Agile dalam konteks pengembangan sistem informasi yang difokuskan pada proses bimbingan tugas akhir di institusi pendidikan tinggi. Metode Agile, dengan pendekatan iteratif dan keterlibatan aktif dari pihak-pihak terkait, dapat memberikan fleksibilitas yang lebih besar dalam menghadapi perubahan kebutuhan, yang seringkali muncul dalam proses bimbingan tugas akhir. Selain itu, metode ini memungkinkan pembuatan sistem informasi berkelanjutan dan pengujian yang lebih baik, yang merupakan elemen penting dalam memastikan kualitas dan kepuasan pengguna yang lebih tinggi. Penelitian ini melibatkan analisis terhadap  peningkatan monitoring tugas akhir mahasiswa dalam lingkungan pendidikan tinggi. Hasil penelitian ini diharapkan akan memberikan wawasan yang berharga bagi lembaga-lembaga pendidikan tinggi yang ingin meningkatkan proses bimbingan tugas akhir mereka dengan memanfaatkan pendekatan Agile dalam pengembangan sistem informasi. Selain itu, penelitian ini juga dapat memberikan kontribusi pada pemahaman lebih mendalam tentang efektivitas metode Agile dalam lingkungan pendidikan tinggi untuk peningkatan efisiensi, kualitas, dan kepuasan pengguna baik kaprodi, dosen dan mahasiswa dalam proses bimbingan tugas akhir.
Sistem Pakar Pendeteksi Penyakit Tanaman Jamur Tiram Menggunakan Metode Certainty Factor Berbasis Web
Authors: Rhido Rezwana  , Dwinita Arwidiyarti  , Hendri Ramdan
Published: May 2024

Jamur tiram merupakan salah satu komoditi pertanian di Indonesia. Jamur tiram dapat dioleh menjadi berbagai macam masakan dan kudapan sehingga kebutuhan akan jamur tiram di masyarakat semakin lama semakin meningkat. Berdasarkan data dari Balai Perbenihan dan Proteksi Tanaman Perkebunan Provinsi Nusa Tenggara Barat, produksi jamur tiram di Provinsi NTB pada tahun 2022 mengalami penurunan sebesar 28.291 kg jika dibandingkan dengan tahun 2021. Berbagai faktor pengganggu seperti serangan hama dan penyakit, iklim dan kesalahan dalam pemeliharaan menjadi penyebab turunnya produksi. Keterbatasan pengetahuan petani dalam mendiagnosis penyakit pada tanaman jamur tiram seringkali mengakibatkan kesalahan yang berdampak pada gagal panen. Tujuan dari penelitian ini adalah menghasilkan sistem pakar yang dapat mendiagnosis penyakit pada tanaman jamur tiram dan memberikan solusi sehingga petani dapat melakukan upaya-upaya pencegahan dan penanganan dengan cepat sebelum penyakit menular ke tanaman jamur tiram lainnya. Sistem pakar ini dibangun dengan menggunakan metode pengembangan perangkat lunak Waterfall. Pengujian fungsional menggunakan Metode Black Box Testing dengan hasil 100% valid sedangkan pengujian akurasi dilakukan dengan menggunakan 20 kasus yang menghasilkan 19 kasus valid (akurasi 95%). Sistem pakar ini menggunakan Metode Certainly Factor berbasis web sehingga dapat diakses oleh petani jamur tiram atau siapapun yang membutuhkan secara gratis. Diharapkan dengan adanya sistem pakar ini dapat membantu petani dalam mendeteksi penyakit pada tanaman jamur tiram dan meningkatkan hasil produksi jamur tiram di masyarakat.
Komparasi Metode Naive Bayes dan K-Nearest Neighbors Terhadap Analisis Sentimen Pengguna Aplikasi Zenius
Authors: Abdillah Tegar , Khaira Ulfa , Hutabarat Benedika Ferdian
Published: May 2024

Tujuan dari penelitian ini adalah untuk membandingkan kinerja metode Naive Bayes dan K-Nearest Neighbor (KNN) dalam menganalisis sentimen pengguna pada aplikasi Zenius. Evaluasi dilakukan dengan memeriksa skor presisi, presisi, recall, dan F1-Score kedua metode serta memvisualisasikan hasil analisis sentimen dengan salah satu metode yang digunakan. Keuntungan dari penelitian ini adalah pemahaman yang lebih mendalam tentang cara kerja teknik Naive Bayes dan KNN dalam analisis sentimen dalam konteks aplikasi Zenius. Lebih lanjut, penelitian ini bertujuan untuk mengevaluasi hasil kinerja dua teknik, Naive Bayes dan KNN, dalam analisis sentimen. Dari hasil pengujian skenario split data menggunakan Split Validation dengan data training dan testing data 90:10. Akurasi Naive Bayes mencapai 88,41%, sedangkan KNN mencapai 100%. Pada penelitian ini, KNN mengungguli Naive Bayes dalam hal nilai presisi, recall, dan F1-Score. Hasil visualisasi data menunjukkan arah sentimen yang dihasilkan cenderung positif. Studi ini tidak hanya memberikan pemahaman lebih dalam tentang kinerja teknik Naive Bayes dan KNN dalam analisis sentimen untuk aplikasi Zenius, namun juga memberikan evaluasi komprehensif terhadap kinerjanya. Penelitian ini diharapkan dapat menjadi panduan untuk mengembangkan metode analisis sentimen yang lebih efektif untuk aplikasi serupa di masa depan.
The Power of Perception: Exploring Country Image, Quality, Value, and Repurchase Intentions in Chinese Smartphone Brands
Authors: Firmansyah* Yayan , Hardiyanto Nugroho , Rafdinal Wahyu , Juniarti Cahaya
Published: May 2024

The role of a country's image in changing consumer views can encourage consumers to repurchase products from that country. This study focuses on the effect of a country's image on repurchase intentions with the additional influence of perceived value and perceived quality. This research method uses an explanatory method with a quantitative approach. The sampling technique used is purposive sampling technique with smart phone users and has purchased Chinese brand smart phones more than twice as a sample. The results obtained show that country image has a significant effect on repurchase intention, besides that other constructs such as perceived value and perceived quality also have a significant effect on repurchase intention.
Keywords: Country Image; Perceived Quality; Perceived Value; Repurchase Intention; Smartphone
Abuse potential of fentanyl and fentanyl analogues
Authors: Thumma Anusha , Mfoafo Kwadwo , Babanejad Niloofar , Omidian Alborz , Omidi Yadollah , Omidian Hamid
Published: May 2024

Introduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. Methods: A literature search was conducted on Web of Science, PubMed, and Google Scholar databases, using the following keywords: fentanyl, illicit fentanyl, deaths, misuse, abuse, and naloxone. We included only articles whose abstracts were available in English. All articles were screened using their abstracts to determine their relevance to the current review. Results: The gold standard for treating both acute and chronic pain is fentanyl, but abuse of the drug has exploded globally since the late 2000s. Fentanyl abuse has been shown to frequently result in serious harm and even death. Conclusions: By educating patients and physicians, making rescue kits easily accessible, developing vaccines to prevent opioid addiction, and perhaps even creating new tamper-resistant fentanyl formulations, it may be possible to prevent fentanyl misuse, therapeutic errors, and the repercussions that follow.
Optical methods of noninvasive glucose measurement
Authors:   Novosibirsk State Technical University, Kashtanov A.A. , Reva I.L. , Kashtanova E.V.
Published: May 2024

In recent decades, the need to develop non-invasive methods for measuring blood glucose levels to facilitate continuous monitoring of this indicator has increased significantly. This is due to a large increase in the incidence of diabetes worldwide. However, there are many problems associated with non-invasive glucose monitoring that contribute to inaccurate results. This article discusses and classifies non-invasive methods for measuring glucose based on its properties over the past 20 years. The main focus is on the relevant physiological aspects, existing problems, and recent advances that have made it possible to obtain acceptable clinical accuracy.
Wobenzyme: correction of coronary disease yhearts and possiblemechanisms of action
Authors:   FSBEI HE «Lipetsk State Pedagogical University named after P.P. Semenov-Tyan-Shansky», Golovanov S.A. , Rasulov M.M. ,   SSC RF «State Research Institute of Chemistry and Technology of  Organoelement Compounds»
Published: May 2024

The effect of Wobenzym on hemostasis, rheological properties of blood, and the clinical course of the disease when included in the complex therapy of angina pectoris was studied. It has been established that Wobenzym improves the rheologicalproperties of blood by reducing the aggregation ability of erythrocytes and platelets andincreasing the deform- ability of erythrocyte membranes. Wobenzym helps optimize the activity of the fibrinolytic and coagulation systems of the blood, improves the clinical course of angina pectoris and the quality of life of patients. The use of Wobenzym as part of complex therapy for patients with angina pectoris of functional class II is clinically justified, effective and safe.
Triastin property to stimulate physical workability
Authors:   SSC RF “State Research Institute of Chemistry and Technology ofOrganoelement Compounds”, Rasulov M.M. , Rybakov Y.L. , Gukasov V.M. , Myakinkova L.L. , Begmetova M.Kh. , Kuznetsov I.A. , Golovanov S.A. , Zhigacheva I.V. , Magun T.Ya.
Published: May 2024

It was revealed that under the influence of the dietary supplement triastin, which includes trekrezan — tris-(2- hydroxyethyl)-ammonium-o-cresoxy-acetate andvarious additional components, prevents the consequences of excessive physicaloverload of the girls’ body in conditions of sports training. A comparative analysis of theeffects of dietary supplements showed that after the completion of courses of taking bothtrekrezan (analogue) and triastine, such indicators as MIC, Astrand Index, MET, DP SAO W 3 min VEM, BP recovery time, time of VEM, characterizing — stenting to physical activity, undergo statistically significant changes. The analysis of adaptive rearrangements under the influence of the biologically active additives studied by usallows us to substantiate a more effective system of complex influence in order to improvethe adaptation processes. The data obtained allow us to formulate a number of tasks forconducting systematic studies of the effects of triastine and similar dietary supplements.
THE ROLE OF THE EDUCATION SYSTEM IN THE FORMATION OF THE INNOVATION FIELD OF NATIONAL ECONOMY
Authors:   Plekhanov Russian University of Economics, Turkovsky S. R.
Published: May 2024

The article is devoted to clarifying the role and place of higher education in innovative systems in the context of the knowledge economy formation. The relationship between the categories “innovative economy", “information socie-ty” and “knowledge economy” is shown. The content of the “innovation system” category is dis-closed and its compo-nents are highlighted. The additional importance of innovation systems in the context of deglobalization and increased geo-economic turbulence is emphasized. The generalized structure of the innovation process is given and three enlarged components of the innovation system (science, education and business) are identified. The role of universities is stated as an integrating component of the innovation system, within which knowledge is generated, accumulated, used and dis-seminated, as well as obtaining a synergistic effect from the interaction of all subjects of innovation activity. The econom-ic importance of the higher education system is emphasized, at the individual level expressed in the growth of household incomes due to the increase in the level of wages, and at the national level –in the increase in the rate of return on capi-tal investments. Three key public functions of higher education have been identified – the increment in human capital, the increase in the adaptability of the economy to innovations and the activation of knowledge diffusion processes. The importance of human capital in the formation of the innovative society susceptibility is emphasized, as well as the need to match the structure and functions of modern universities to solving the problems of ensuring the processes of network knowledge production, the formation of sufficient quantitative and corresponding to the tasks of intensive economic de-velopment qualitative parameters of human capital at the national and regional levels and the formation of multilateral innovation networks. The necessity is substantiated and the tasks of changing the role and modernizing the function of the higher education system in connection with activating the processes of the society digital transformation in the condi-tions of the fourth industrial revolution are clarified.
REGIONAL AND MUNICIPAL INTERACTION IN THE SPHERE OF USING DIGITAL PUBLIC MANAGEMENT TOOLS
Authors:   Russian University of Cooperation, Sidorov M. A.
Published: May 2024

The processes of digital transformation, which are becoming increasingly important in the global economy, are now increasingly active in such spheres as public administration, which are not directly related to production activities. During the first decade of the XXI century, the digitalization of the Russian public administration system primarily consist-ed in the formation of a number of federal information systems, but by the end of the second decade, the regional level began to show increasing dynamics of implementation of digital tools. In the framework of the regional digital transfor-mation, the main difference from the federal one is the presence at the grassroots level of a number of autonomous mu-nicipal organizations that are not subordinate to the regional center and in some cases have their own vision of this pro-cess. Under such conditions, municipal-regional interaction in the field of digital tools of public administration acquires great importance. However, this process is characterized by a low level of formalization and can look like a set of unrelat-ed functional processes, which leads to the lack of comprehensive research in this area. At the same time, the process of regional-municipal interaction, according to the hypothesis of this study, is a complex of interrelated elements based on economic factors, the violation in the practical implementation of each of which contributes to the formation of prerequi-sites for the inefficient use of digital tools. Thus, the purpose of this study is to analyze the structure and composition of the regional-municipal interaction in the framework of the use of digital tools of public administration. On the basis of the goal, the study defined a number of tasks, including the definition of the essence of this interaction, identifying its struc-ture and composition. The study was based on the normative legal acts of public authorities, official digital publications of state and municipal organizations, scientific publications on the digitalization of public administration. According to the results of the study, the basic elements of interaction, their interrelations, and the associated potential risks of disruption of the effective use of digital tools were identified.
ANTI-CORRUPTION BEHAVIOR MODEL OF CUSTOMS OFFICIALS: ASSESSING THE IMPACT OF DIGITAL TOOLS
Authors:   Pskov State University, Vasilyeva M. V.
Published: May 2024

The work systematizes and defines the role of anti-corruption policy for the harmonious development of so-ciety and security of the national economy. Relevance of the research topic is confirmed by the state’s demand for improving the effectiveness of anti-corruption policy in the customs sphere, it is necessary to assess the factors deter-mining the formation of anti-corruption behavior model of representatives of state structures. The author emphasizes the importance of using the experience of the international customs community, including in the format of the regula-tory framework: the Arusha Declaration, the Framework of Standards to Secure and Facilitate International Trade, PICARD educational standards. The article presents the potential of applied tools for controlling the activities of customs officials in Russia with a focus on national regulations and digital services. The materials include the results of theoretical and analytical and practical studies of the influence of factors on the formation of anti-corruption behavior of customs officials, an assessment of the strategic priorities of the customs service in the context of anti-corruption goals and measures is given.Particular attention is paid to IT-technologies in the customs sphere, assessing their potential in counteracting and preventing corruption. The author compares the sources of corruption and specifies the digital tools of customs administration as applied to the leveling of these risks on the basis of the map of corruption risks and measures to minimize them. The author proposes a behavior model of customs officials, including the estimated values of the influence of environmental factors. It is concluded that the further development of digital services to reduce corruption risks is important, but along with the technical approach, it is necessary to increase attention to the educa-tional work in the customs authorities and expand anti-corruption education in the state as a whole.
Interoperability of EU information systems – a tool to fight terrorism and serious cross-border crime (Part II)
Authors:   Central Forensic Laboratory of the Police, Kot Edyta
Published: May 2024

A key element of the counter-terrorism strategy is to protect citizens from terrorist attacks and to level the consequences of such attacks. This is possible by improving border security, transportation and cross-border infrastructure. No less important part of the strategy is the prosecution of terrorists, especially those with an international dimension. EU member states in favour of thwarting terrorists have the tools to share information, intelligence, threat analysis and strengthen operational law enforcement cooperation. The European Union has also developed legal and organisational instruments to assist in the fight against terrorism and organized cross-border crime.
Sustainable Optimization of Mold Heating: A Dual Approach with SWARA and MARCOS Methods
Authors: Peker Rahim Can , Karakurt Asım Sinan
Published: May 2024

There are many methods and raw materials used in the manufacture of Fiber Reinforced Plastics (FRP) by hot molding, such as Sheet Molding Compound (SMC), Bulk Molding Compound (BMC), and Prepreg fabrics. In most applications, it is common practice to insert the new dough into the mold without cooling it, then re-press and cure. Placing the mold in the dough without cooling causes the surface of the molded product to cure faster than the inner region, resulting in a structurally discontinuous structure in the product. Therefore, in more professional production, the mold is lowered to around 120 oC and the dough is poured into the mold at this stage. However, this increases energy consumption and carbon emissions for the heating and cooling phases. This study investigated the energy efficiency of the production of FRP using the hot-pressing process. At the end of this study, by using alternative energy methods in the manufacturing processes, results such as investment costs, depreciation costs, reductions in bills, and carbon emissions were achieved. To find the best alternative from these results, the criteria weights were determined using SWARA, and the alternatives identified were ranked using the MARCOS method. As a result of this ranking, the best alternative was determined to be a 40 kWh battery and a 25 kW solar panel option among the solar panel power and battery capacity alternatives.
Verification of the Interrelationship between General Strain Factors and the Occurrence of White-Collar Crime : Focused on Differences of job levels
Authors:   The Correction Welfare Society of Korea, Lee Seung woo , Nam Jae Sung
Published: May 2024

The purpose of this study is verifying the impact on white-collar crime intentions through applying general strain theory, particularly by categorizing white-collar workers into subordinates, middle managers, and executives, and comparing the differences in criminal intention depends on their job levels. The intention for white-collar crime, specifically focusing on embezzlement, was suggested as The dependent variable. Also, rather than direct measurement about embezzlement, and respondents were prompted to response their behaviors and perceptions in specific situations with suggested crime scenarios The independent variables included strain factors proposed by the General Strain Theory, such as the loss of positive stimuli, failure to achieve goals, and the occurrence of negative stimuli, along with negative emotions. To achieve the goal of this research, data was collected focusing on office, business, and management workers in the metropolitan area. As a result, general strain factors did not affect to the intent for white-collar crime at the executive level. However, it was suggested that the smaller the size of the company, the more significant affect on the intention for white-collar crime. In the case of subordinate and middle management workers, both general strain factors and negative emotions affected significantly to the intention for white-collar crime. Therefore, to counteract white-collar crime, it is requested the differentiated strategies for each job levels. For small and medium-sized enterprises, controls to executives should be strengthened, and for large enterprises or conglomerates, a fair promotion system and adequate economic rewards, such as appropriate wage increasing, should be enhanced to mitigate the feelings of deprivation among lower-level employees and middle managers.
The Influence of the Nagetive Parent Attitude on the Aggression of an Adolescent: Focused on the Mediating Effect of the Grit and the Social Withdrawal
Authors:   The Correction Welfare Society of Korea, Jeong Il-Young
Published: May 2024

This study’s purpose was to prove the mediating effect of the grit and the social withdrawal within the direct path which the parents' negative parent attitude have effected to the aggression of an adolescent. For archiving this research purpose, this study have selected a total of 2,384 cases who were third grade in middle school(a year of 2020) from Korea Youth Pannel Survey(KYPS) 3th wave applicable in the year 2018 as an analysis target. And this study have applied Structural Equation Modeling(AMOS 18.0) as an core analysis method, sobel test for demonstrating the indirect effect of the mediating path. Base on the above research method, this study have established the research results as below. First, this study have found out the direct effect between the parents' negative rearing attitude and the aggression of an adolescent. Second, this study have proved the indirect effects of the grit and the social withdrawal. Through the presented research results, this study have suggested the practical implication reducing the aggression of an adolescent and the suggestion for the prior study.
Lehrkräftemangel in Österreich. Bestandsaufnahmen und Initiativen
Authors: Schnider Andreas , Braunsteiner Maria-Luise
Published: May 2024

Im vorliegenden Artikel werden Ursachen des Lehrkräftemangels in Österreich (Pensionierung, Teilzeit) und Ausprägung (Bedarfszahlen) dargestellt sowie die 2013 initiierte Neuorganisation der Lehrkräftebildung. Für die bildungspolitische Initiative der Rekrutierung von Quereinsteiger*innen wurde ein mehrstufiges Aufnahmeverfahren und ein mit allen Hochschulen erarbeiteter berufsbegleitender Hochschullehrgang entwickelt. Die Bewerbungen dafür übersteigen die Erwartungen um das Zehnfache. Damit decken Lehramtsstudierende, Überstunden von Lehrer*innen und Quereinsteiger*innen den Bedarf ab.
Studentische Aushilfslehrkräfte zwischen Professionalisierungserwartungen und Krisenmanagement
Authors: Artmann Michaela , Rakoczy Katrin , Seifert Anja
Published: May 2024

Der im Projekt „Professionalität und Professionalisierungsprozesse studentischer Aushilfs- und Vertretungslehrkräfte (PROSA)“ entstandene Beitrag stellt erste Befunde aus einer quantitativen und zwei qualitativen Vorstudie(n) zu Rahmenbedingungen studentischer Aushilfslehrtätigkeit, den damit verbundenen Aufgaben von studentischen Lehrkräften sowie der Übersetzung von Rollenzuweisungen in ein eigenes Rollenverständnis vor. Dabei zeigt sich das Suchen nach der eigenen Position bei vagem, z. T. auch widersprüchlichem Status als zentrale Herausforderung in der studentischen Vertretungstätigkeit.
Presencia de Eimeria spp. en Gallus domesticus comerciales en las provincias de Pichincha y Santo Domingo de los Tsáchilas, Ecuador
Authors:   , Cevallos Gordon Ana Luisa
Published: May 2024

La coccidiosis aviar es una parasitosis de importancia económica para la industria avícola. En Ecuador existe escasa información sobre la presencia de Eimeria spp. en las granjas comerciales de pollos parrilleros, por lo que se analizaron 155 establecimientos en las provincias de Pichincha y Santo Domingo de los Tsáchilas. A través del análisis de heces frescas se determinó la carga parasitaria y por PCR las diferentes especies de Eimeria. Además, se realizó una encuesta epidemiológica para determinar los factores de riesgo de infección. Se observó que todas las muestras eran positivas a la presencia de Eimeria spp., pese a que todas mantenían medidas profilácticas; aun así, en ninguna se observó coccidiosis clínica. La carga parasitaria varió entre 25 y 169.700 OPG. La prevalencia por especie fue E. maxima 80.4%, E. acervulina 70.6%, E. praecox 55.4%, E. tenella 53.6%, E. necatrix 52,2% y E. brunetti 30.8%. A través de regresión logística multivariable, se observó que las granjas de productores independientes tenían alta probabilidad de presentar mayor carga de Eimeria spp., E. brunetti, E. necatrix, E. praecox y E. tenella. Los galpones avícolas que estaban a menos de 1300 msnm se asociaron con mayor OPG y presencia de E. brunetti. Las aves menores de 35 días de edad y los galpones avícolas abiertos (con rudimentario control ambiental), tenían mayor probabilidad de presentar E. maxima. Si el agua de bebida provenía de pozos, el riesgo de E. praecox era mayor. El tiempo de vacío sanitario, tamaño de las granjas avícolas, desinfectantes, y el resto de los factores evaluados, no presentaron riesgo ni protección en relación a la presencia de Eimeria spp. Serían necesarias más investigaciones tendientes al diseño de estrategias de control para mejorar la gestión en las granjas avícolas.
Tratamiento médico de megacolon
Authors:   , Paxote Manuel José
Published: May 2024

Muchas han sido les definiciones que sobre esta enfermedad se han hecho, pero sin que ninguna goce de aceptación general, ya se trate de la enfermedad de Hirschsprung o del megacolon adquirido. Según algunas definiciones, esta enfermedad está caracterizada anatómicamente por dilatación, elongamiento e hipertrofia de una parte de la totalidad del colon, y clínicamente, por constipación tenaz y distensión abdominal desproporcionada que contrasta con el enflaquecimiento general y que puede llevar a la caquexia por estorcoremia y cuyo comienzo puede datar de la infancia. No se observa obstáculo mecánico que impida el libre tránsito del contenido intestinal. En lo que respecta a etiología, cuestión sumamente valiosa para el tratamiento, existe discrepancia entre los diversos autores que han tratado el tema; ya sea en el mecanismo íntimo de la afección o sobre las causas que gravitan sobre su desarrollo.
INSIGHTS HALAL SUPPLY CHAIN MANAGEMENT AT INDONESIA NUSANTARA FISHERY PORT
Authors: Himawan Abdurrahman Faris Indriya , Razik Muhammad Aslyzan , Mohd Zain Rosmaizura
Published: May 2024

This research was conducted at the Nusantara Fisheries Port (PPN) with a focus on examining the halal supply chain activities among fishers and identifying potential fraudulent practices in fishing operations. Employing a qualitative approach and source triangulation, the study aims to address these issues comprehensively. It sheds light on various stages of the halal supply chain, including fishers’ departure preparations, fish unloading processes at the pier, price determination, and product delivery to factories. Findings reveal prevalent fraudulent activities within fishers' operations leading to the compromised halal status of products. Common fraudulent practices are observed in administrative procedures from departure to docking, often normalized among fishers. Moreover, discrepancies in fish pricing at the port frequently occur due to baseless manipulations by some agents or suppliers.