bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 1 from Tumor-Derived GM-CSF Promotes Inflammatory Colon Carcinogenesis via Stimulating Epithelial Release of VEGF
Authors: Wang Yi , Han Gencheng , Wang Ke , Liu Guijun , Wang Renxi , Xiao He , Li Xinying , Hou Chunmei , Shen Beifen , Guo Renfeng , Li Yan , Chen Guojiang
Published: March 2023

PDF file - 171K, Primer list.
Supplementary Figure 6 from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth
Authors: Barceló Carles , Paco Noelia , Morell Mireia , Alvarez-Moya Blanca , Bota-Rabassedas Neus , Jaumot Montserrat , Vilardell Felip , Capella Gabriel , Agell Neus
Published: March 2023

PDF file - 27K, Figure S6. Detection of the phosphorylated form of oncogenic KRAS in human pancreatic ductal adenocarcinoma by 2-DE.
Supplementary Figure 1 from CD133+ Cancer Stem-like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant but Sensitive to a Novel Neuropeptide Antagonist
Authors: Sarvi Sana , Mackinnon Alison C. , Avlonitis Nicolaos , Bradley Mark , Rintoul Robert C. , Rassl Doris M. , Wang Wei , Forbes Stuart J. , Gregory Christopher D. , Sethi Tariq
Published: March 2023

PDF file - 519KB, Apoptosis in etoposide treated H345 cells and etoposide treated mouse tumors immunostained for CD133 and GRP-R.
Supplementary Figure 2 from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth
Authors: Barceló Carles , Paco Noelia , Morell Mireia , Alvarez-Moya Blanca , Bota-Rabassedas Neus , Jaumot Montserrat , Vilardell Felip , Capella Gabriel , Agell Neus
Published: March 2023

PDF file - 25K, Fig. S2. Quantitation of apoptosis by cleaved caspase-3 measurement.
Supplementary Figure Legend from CCL2/CCR2-Dependent Recruitment of Functional Antigen-Presenting Cells into Tumors upon Chemotherapy
Authors: Ma Yuting , Mattarollo Stephen R. , Adjemian Sandy , Yang Heng , Aymeric Laetitia , Hannani Dalil , Portela Catani João Paulo , Duret Helene , Teng Michele W.L. , Kepp Oliver , Wang Yidan , Sistigu Antonella , Schultze Joachim L. , Stoll Gautier , Galluzzi Lorenzo , Zitvogel Laurence , Smyth Mark J. , Kroemer Guido
Published: March 2023

PDF file - 53K
Supplementary Materials and Methods from Netrin-1 Promotes Medulloblastoma Cell Invasiveness and Angiogenesis, and Demonstrates Elevated Expression in Tumor Tissue and Urine of Patients with Pediatric Medulloblastoma
Authors: Akino Tomoshige , Han Xuezhe , Nakayama Hironao , McNeish Brendan , Zurakowski David , Mammoto Akiko , Klagsbrun Michael , Smith Edward
Published: March 2023

PDF file - 80KB
Supplementary Methods, Figures 1 - 2, Tables 1 - 3 from CXM: A New Tool for Mapping Breast Cancer Risk in the Tumor Microenvironment
Authors: Flister Michael J. , Endres Bradley T. , Rudemiller Nathan , Sarkis Allison B. , Santarriaga Stephanie , Roy Ishan , Lemke Angela , Geurts Aron M. , Moreno Carol , Ran Sophia , Tsaih Shirng-Wern , De Pons Jeffery , Carlson Daniel F. , Tan Wenfang , Fahrenkrug Scott C. , Lazarova Zelmira , Lazar Jozef , North Paula E. , LaViolette Peter S. , Dwinell Michael B. , Shull James D. , Jacob Howard J.
Published: March 2023

Expanded Materials and Methods, Supplemental Figures, and Supplemental Tables Figure S1. Flow cytometric analysis of peripheral blood from SS, SS.BN3, SSIL2Rγ, and SS.BN3IL2Rγ rats. Figure S2.SH2B3 specifically marks CD31+ blood vessels, but not LYVE1+ lymphatic vessels. Table S1. Peripheral blood analysis of SS, SS.BN3, SSIL2Rγ and SS.BN3IL2Rγ rats. Table S2. Genes located in the overlapping portions of the rat chromosome 3 cancer QTLs. Table S3. Variants that cosegregate between tumor resistant (BN and Cop) and tumor susceptible (ACI, F344, and SS) rat strains.
Supplementary Figure Legends from Netrin-1 Promotes Medulloblastoma Cell Invasiveness and Angiogenesis, and Demonstrates Elevated Expression in Tumor Tissue and Urine of Patients with Pediatric Medulloblastoma
Authors: Akino Tomoshige , Han Xuezhe , Nakayama Hironao , McNeish Brendan , Zurakowski David , Mammoto Akiko , Klagsbrun Michael , Smith Edward
Published: March 2023

PDF file - 55KB
Supplementary Materials and Methods and Figure Legends from CBP Loss Cooperates with PTEN Haploinsufficiency to Drive Prostate Cancer: Implications for Epigenetic Therapy
Authors: Ding Liya , Chen Shuai , Liu Ping , Pan Yunqian , Zhong Jian , Regan Kevin M. , Wang Liguo , Yu Chunrong , Rizzardi Anthony , Cheng Liang , Zhang Jun , Schmechel Stephen C. , Cheville John C. , Van Deursen Jan , Tindall Donald J. , Huang Haojie
Published: March 2023

PDF file - 131KB
Supplementary Figure 4 from Bcl2 Induces DNA Replication Stress by Inhibiting Ribonucleotide Reductase
Authors: Xie Maohua , Yen Yun , Owonikoko Taofeek K. , Ramalingam Suresh S. , Khuri Fadlo R. , Curran Walter J. , Doetsch Paul W. , Deng Xingming
Published: March 2023

PDF file - 142K, Expression of exogenous Bcl2 in H1299 cells reduces the formation of hRRM1/hRRM2 complexes, which requires the BH4 domain.
Supplementary Figures 1 - 7 from Novel Bispecific Antibodies Increase γδ T-Cell Cytotoxicity against Pancreatic Cancer Cells
Authors: Oberg Hans-Heinrich , Peipp Matthias , Kellner Christian , Sebens Susanne , Krause Sarah , Petrick Domantas , Adam-Klages Sabine , Röcken Christoph , Becker Thomas , Vogel Ilka , Weisner Dietrich , Freitag-Wolf Sandra , Gramatzki Martin , Kabelitz Dieter , Wesch Daniela
Published: March 2023

PDF file - 2448K, Phenotype of established gamma delta T-cells and PDAC-cell lines (S1); Design and purification of the recombinant Her2xCD3 bsscFv (S2); Her2xCD3 bsscFv enhances the gamma delta T-cell lysis of Panc89 cells (S3); Design and purification of the recombinant (Her2)2xVγ9 tribody (S4); (Her2)2xVγ9 does not mediate lysis of antigen-negative lymphoma cells (S5); Increase of gamma delta T-cell cytotoxicity against Panc89 cells by tribody (Her2)2xVγ9 (S6); Tribody (Her2)2xVγ9 enhances CD107a expression on gamma delta Tcell lines co-cultured with PancTu-I cells (S7).
Data Supplement from Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Authors: Tchaicha Jeremy H. , Akbay Esra A. , Altabef Abigail , Mikse Oliver R. , Kikuchi Eiki , Rhee Kevin , Liao Rachel G. , Bronson Roderick T. , Sholl Lynette M. , Meyerson Matthew , Hammerman Peter S. , Wong Kwok-Kin
Published: March 2023

Supplemental Figure 1. Details about genetically engineered mouse model, with gross tumor lesions present in lung followed about negative FGFR2 IHC (control) and before/after BGJ-398 treatment.
Data Supplement from Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Authors: Tchaicha Jeremy H. , Akbay Esra A. , Altabef Abigail , Mikse Oliver R. , Kikuchi Eiki , Rhee Kevin , Liao Rachel G. , Bronson Roderick T. , Sholl Lynette M. , Meyerson Matthew , Hammerman Peter S. , Wong Kwok-Kin
Published: March 2023

Supplemental Figure 4. Brain lesions that arise after metastasis from the nasal epithelium.
Data Supplement from Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Authors: Tchaicha Jeremy H. , Akbay Esra A. , Altabef Abigail , Mikse Oliver R. , Kikuchi Eiki , Rhee Kevin , Liao Rachel G. , Bronson Roderick T. , Sholl Lynette M. , Meyerson Matthew , Hammerman Peter S. , Wong Kwok-Kin
Published: March 2023

Descriptions of each of the Supplemental Figures/Tables
Supplementary Figure Legends from VISTA Regulates the Development of Protective Antitumor Immunity
Authors: Le Mercier Isabelle , Chen Wenna , Lines Janet L. , Day Maria , Li Jiannan , Sergent Petra , Noelle Randolph J. , Wang Li
Published: March 2023

PDF file - 68K
Supplementary Figure 7 from VISTA Regulates the Development of Protective Antitumor Immunity
Authors: Le Mercier Isabelle , Chen Wenna , Lines Janet L. , Day Maria , Li Jiannan , Sergent Petra , Noelle Randolph J. , Wang Li
Published: March 2023

PDF file - 21K, The therapeutic efficacy of vaccine/VISTA mab combination treatment requires T-cell mediated adaptive immune response.
Supplementary Figure 5 from VISTA Regulates the Development of Protective Antitumor Immunity
Authors: Le Mercier Isabelle , Chen Wenna , Lines Janet L. , Day Maria , Li Jiannan , Sergent Petra , Noelle Randolph J. , Wang Li
Published: March 2023

PDF file - 6K, Representative flow cytometry plots for the expression of IFNγ and granzyme B, and Ki67, and CD107 surface mobilization by tumor-infiltrating CD8+ T cells, as well as expression of IL12p40 and TNFalpha production by tumor-infiltrating DCs.
Supplementary Figure 3 from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

PDF file - 220K, MiR-221 down-regulation predicts clinical failure (CF) in high-risk prostate cancer.
Supplementary Figure 2 from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

PDF file - 229K, Scatter- and Box blots show the expression of miR-221 in the study- and validation cohort in relation to clinical/histopathological parameters.
Supplementary Table 1 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Authors: Guillemette Shawna , Branagan Amy , Peng Min , Dhruva Aashana , Schärer Orlando D. , Cantor Sharon B.
Published: March 2023

PDF file - 43K, Supplemental Table 1. FANCJ suppresses UV-induced mutations at the HPRT locus.
Supplementary Figure 8 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Authors: Guillemette Shawna , Branagan Amy , Peng Min , Dhruva Aashana , Schärer Orlando D. , Cantor Sharon B.
Published: March 2023

PDF file - 119K, Supplemental Figure 8. Ectopic expression of catalytic inactive FANCJK52R disrupts clearance of UV induced lesions in U2OS cells
Supplementary Methods from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 81K
Supplementary Figure 2 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Authors: Guillemette Shawna , Branagan Amy , Peng Min , Dhruva Aashana , Schärer Orlando D. , Cantor Sharon B.
Published: March 2023

PDF file - 260K, Supplemental Figure 2. MMR localizes FANCJ to UV induced LUDs
Supplementary Figure 8 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 4294K, This figure shows that fibronectin level is regulated by GPR56 in a similar manner to that of TG2.
Supplementary Figure 3 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 377K, This figure shows the immunohistochemical analyses using the anti-Ki67 antibody or TUNEL stain on tumor sections.
Supplementary Table 2 from High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development
Authors: Lin Dong , Wyatt Alexander W. , Xue Hui , Wang Yuwei , Dong Xin , Haegert Anne , Wu Rebecca , Brahmbhatt Sonal , Mo Fan , Jong Lina , Bell Robert H. , Anderson Shawn , Hurtado-Coll Antonio , Fazli Ladan , Sharma Manju , Beltran Himisha , Rubin Mark , Cox Michael , Gout Peter W. , Morris James , Goldenberg Larry , Volik Stanislav V. , Gleave Martin E. , Collins Colin C. , Wang Yuzhuo
Published: March 2023

XLSX file - 37K, Supplementary Table 2: Gene expression signature associated with predisposition to neuroendocrine transdifferentiation.
Supplementary Table 1 from High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development
Authors: Lin Dong , Wyatt Alexander W. , Xue Hui , Wang Yuwei , Dong Xin , Haegert Anne , Wu Rebecca , Brahmbhatt Sonal , Mo Fan , Jong Lina , Bell Robert H. , Anderson Shawn , Hurtado-Coll Antonio , Fazli Ladan , Sharma Manju , Beltran Himisha , Rubin Mark , Cox Michael , Gout Peter W. , Morris James , Goldenberg Larry , Volik Stanislav V. , Gleave Martin E. , Collins Colin C. , Wang Yuzhuo
Published: March 2023

XLSX file - 10K, Supplementary Table 1: Growth inhibition of transplantable tumor lines after Bicalutamide treatment.
Supplementary Figure 1 from Genetic Suppression of Inflammation Blocks the Tumor-Promoting Effects of TGF-β in Gastric Tissue
Authors: Ota Mitsuhiko , Horiguchi Masahito , Fang Victoria , Shibahara Kotaro , Kadota Kyuichi , Loomis Cynthia , Cammer Michael , Rifkin Daniel B.
Published: March 2023

PDF file - 185KB, A. Survival, B. Weight, C. Organ Weight/Body Weight, D. Spleen, E. Total TGFbeta1 Level (pg/ml), F. Active TGFbeta1 Level (pg/ml).
Supplementary Figure S2 from Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers
Authors: Krishnan Vidhya G. , Ebert Philip J. , Ting Jason C. , Lim Elaine , Wong Swee-Seong , Teo Audrey S.M. , Yue Yong G. , Chua Hui-Hoon , Ma Xiwen , Loh Gary S.L. , Lin Yuhao , Tan Joanna H.J. , Yu Kun , Zhang Shenli , Reinhard Christoph , Tan Daniel S.W. , Peters Brock A. , Lincoln Stephen E. , Ballinger Dennis G. , Laramie Jason M. , Nilsen Geoffrey B. , Barber Thomas D. , Tan Patrick , Hillmer Axel M. , Ng Pauline C.
Published: March 2023

Percentage of somatic variants based on 6 mutation types in Asian lung cancers.
Supplemental Figures 1-3 from The Alarmin HMGN1 Contributes to Antitumor Immunity and Is a Potent Immunoadjuvant
Authors: Wei Feng , Yang De , Tewary Poonam , Li Yana , Li Sandra , Chen Xin , Howard O.M. Zack , Bustin Michael , Oppenheim Joost J.
Published: March 2023

Supplemental Figures 1-3. sFig. 1: Uppregulation of DC CD80, CD86, and I-A/E in response to HMGN1. sFig. 2: Comparison of in vitro proliferation and in vivo tumor generation of control and HMGN1-expressing EL4 tumor cells. sFig. 3: Analysis gating strategy for determination of IFNγ-producing CD8 T cells.
Supplementary Methods from An Antibody–Drug Conjugate That Targets Tissue Factor Exhibits Potent Therapeutic Activity against a Broad Range of Solid Tumors
Authors: Breij Esther C.W. , de Goeij Bart E.C.G. , Verploegen Sandra , Schuurhuis Danita H. , Amirkhosravi Ali , Francis John , Miller Vibeke Breinholt , Houtkamp Mischa , Bleeker Wim K. , Satijn David , Parren Paul W.H.I.
Published: March 2023

PDF file - 27K, Antibody cross-competition studies; Alphascreen Assay to detect ERK phosphorylation.
Supplementary Figure Legends from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: March 2023

PDF - 73KB, Legends for Supplementary Figures.
Supplementary Figure 9 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: March 2023

PDF - 429K, KCNA1 expression in different breast cancer subgroups.
Supplementary Figure 7 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: March 2023

PDF - 1285KB, PKA activation favors OIS escape.
Supplementary Materials and Methods, Figure Legends, Tables 1 - 5 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 154KB, Table S1. Cell lines, media. Table S2. Pre-miRs and anti-miRs. Table S3. Primers. Table S4. Antibodies. Table S5. Clinical characteristics of the tumor-samples used in Figure 7.
Supplementary Figure 2 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: March 2023

PDF - 923KB, KCNA1 impacts RAF-induced hallmarks of OIS.
Supplementary Figure 5 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 145KB, Expression of exogenous NDY1/KDM2B rescues the shNDY1 phenotype.
Supplementary Figure 4 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 3478KB, Knockdown of NDY1/KDM2B promotes differentiation of human mammary adenocarcinoma cell lines in culture.
Supplementary Figure 3 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 139KB, The knockdown of NDY1/KDM2B interferes with the replating efficiency of mammospheres from both basal and luminal mammary adenocarcinoma cell lines.
Supplementary Table and Figure Legends from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: March 2023

Supplementary Table and Figure Legends. Legend for Supplementary Tables S1-S2 and Supplementary Figures S1-S4.
Supplementary Figure 1 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 78KB, The NDY1/KDM2B knockdown inhibits anchorage-dependent and independent growth of cancer cells.
Supplementary Figure S3 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: March 2023

Supplementary Figure S3. HMGB1 produced by tumor cells promotes tumor growth and metastasis.
Supplementary Methods from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 111K
Supplementary Figure 6 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 54K, Effect of gamma-secretase inhibitor on the NOTCH1 pathway genes and cell growth in HNSCC cells with NOTCH1 wildtype status. UPCI-SCC090 cells were growing on the media supplemented with 0.2 uM gamma-secretase inhibitor XXI (GSI-XXI) for up to 72 hours. The effect of GSI-XXI on the NOTCH1 targets HES1 and HEY1 is shown on the left for UPSI-SCC090 cell line.
Supplementary Table 1 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 116K, Correlation between expression of HIC1 and clinical pathological features in tissue microarrays.
Supplementary Figure 2 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 169K, NOTCH pathway activation in HNSCC. A, Immunohistochemical analysis of NOTCH1, HES1 and HEY1 protein expression in HNSCC. Tissue microarray arrays with quadruplicates of samples from each of 56 HNSCC tumor and 11 non-tumor patients were stained with anti-NOTCH1, anti-HES1 or anti-HEY1 antibody, as described in methods. Top, the heat-map of immunohistochemical analysis for tissue microarray slides. Rows, genes; column, each individual sample. The average staining for four tissues was categorized to Strong (brown), Moderate (grey) or Weak/Negative (blue) staining. Samples are ranked by the pathology ID numbers in tumor (left) and normal (right) groups. Bottom: quantification of immunohistochemical data. The number and percentage of tumor (Tu) and normal (No) patient in strong, moderate and weak/negative category was quantified. P-values were calculated by comparing numeric scores in tumor vs normal sample by independent t test. The samples 57964, 58602, 22146, 5931, 26514 represent tumor samples X6, X7, X11, X28 and X34 from the original discovery cohort of 44 HNSCC tumors. B, Representative immunohistochemical results. The representative slides of positive or moderate staining are shown for tumors and compared to normal tissue. Bar, 100 um equivalent. Tumor (T) and normal (N) tissues on each sample are labeled. ID 22146 represented X11 samples, which were used both in array and in immunohistochemical analysis, where protein and RNA expression strongly correlate.
Supplementary Figure Legend from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 111K
Supplementary Figure 1 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 73K, Significant overexpression of JAG1 (A) and PSEN1 (B) in the tumors with increased copy number gains in comparison to that in the normal tissues in the cohort of 44 HNSCC tumors and 25 normal mucosa. N, normal mucosa; T, HNSCC tumors; -, without JAG1(A) or PSEN1 (B) copy number gain; +, with JAG1 (A) or PSEN1 (B) copy number gain. Boxes represent the interquartile range (25th-75th percentile) and horizontal lines inside the boxes indicate median. Whiskers indicate the minimum and maximum values. P value was calculated by using t test.
Supplementary Figure 5 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 570K, LCN2 promotes lung metastasis in balb/c nude mice.
Video S3 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

AVI file 50842K, circulation in solvent control embryo
Video S2 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

MOV file 5444K, circulation in Enox1 morphant
Fig S2 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

PDF file 1425K, Confocal immunofluorescent imaging of Enox1 in zebrafish embryo heart, tail and chondrocytes
Supplementary Figure 1 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: March 2023

PDF file, 7478K, Identification of NFATc1-positive tumor cells in human breast tumor specimens.
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: March 2023

Supplemental Figure 2. MDSC subsets in the lungs of naive mice and in vitro suppressive activity of tumor-bearers' MDSC.
Supplementary Figure 7 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 73K, BCL2l12 does not change the rate of proliferation and apoptosis.
Supplementary Methods from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 48K
Supplementary Figure 3 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: March 2023

PDF file - 21KB, UTX depletion did not affect the expression of Rb gene and other Rb pathway genes.
Supplementary Figure 7 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 134K, Telomere Length Analysis by 5p Genotype.
Supplementary Table 1 from Extracellular RNA Liberates Tumor Necrosis Factor-α to Promote Tumor Cell Trafficking and Progression
Authors: Fischer Silvia , Gesierich Sabine , Griemert Barbara , Schänzer Anne , Acker Till , Augustin Hellmut G. , Olsson Anna-Karin , Preissner Klaus T.
Published: March 2023

PDF-64K, Number of seeded living and transmigrated tumor cells.
Supplementary Movie 5 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

AVI file - 956KB, Dynamics of ARv7 variant nuclear accumulation in cells treated with 10nM Noc.
Supplementary Movie 4 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

AVI file - 749KB, Dynamics of ARv7 variant nuclear accumulation in untreated cells.
Supplementary Movie 3 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

AVI file - 503KB, Dynamics of ARv567 variant nuclear accumulation in cells treated with 1nM TXT.
Supplementary Movie 2 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

AVI file - 681KB, Dynamics of ARv567 variant nuclear accumulation in cells treated with 10nM Noc.
Supplementary Figure 2 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: March 2023

PDF file - 1914KB, Cdk1 is responsible for Taxol-induced TAZ phosphorylation and degradation.
Supplementary Movie 1 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: March 2023

AVI file - 712KB, Dynamics of ARv567 variant nuclear accumulation in untreated cells.
Supplementary Figure 3 from NUP98 Fusion Oncoproteins Promote Aneuploidy by Attenuating the Mitotic Spindle Checkpoint
Authors: Salsi Valentina , Ferrari Silvia , Gorello Paolo , Fantini Sebastian , Chiavolelli Francesca , Mecucci Cristina , Zappavigna Vincenzo
Published: March 2023

PDF - 2287K, Supplementary Figure 3. Mitotic index in transfected and in nocodazole arrested HEK293 cells. A, Mitotic index of control untransfected, nocodazole-arrested HEK293 and U937 cells. Cells were labelled with a specific anti-phosphoSer10 antibody and analysed by flow citometry. B, Immunoblot analysis of the expression of the indicated proteins in HEK293 cells transiently transfected with expression constructs for NUP98, NUP98-HOXD13, NUP98-LOC, NUP98-HHEX, treated with nocodazole, and harvested at the indicated time points. An arrowhead indicates the NUP98-HOXD13 band just below that of endogenous NUP98. CyclinB1 (CCNB1), Geminin (GMN) and securin (SEC) amounts were detected C, HEK293 cells, transiently transfected with expression constructs for the indicated proteins, were labelled with a specific anti-phosphoSer10 antibody and analysed by flow citometry.
Supplementary Methods from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

PDF file - 93K
Supplementary Figure Legend from A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
Authors: Barsoum Ivraym B. , Smallwood Chelsea A. , Siemens D. Robert , Graham Charles H.
Published: March 2023

PDF file - 73K
Supplementary Movie 6 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

MP4 file - 1833K, Supplementary movie S6: time-lapse video-microscopy with a 10x magnification objective, of Lu1205 cells plated on plastic 48 hr after si ICAT transfection.
Supplementary Movie 5 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

MP4 file - 2929K, Supplementary movie S5: time-lapse video-microscopy with a 10x magnification objective, of Mel501 cells plated on plastic 48 hr after si ICAT transfection.
Supplementary Movie 3 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

MP4 file - 3337K, Supplementary movie S3: time-lapse video-microscopy with a 10x magnification objective, of Lu1205 cells plated on plastic 48 hr after MOCK transfection.
Supplementary Movie 2 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

MP4 file - 3502K, Supplementary movie S2: time-lapse video-microscopy with a 10x magnification objective, of Mel501 cells plated on plastic 48 hr after ICAT transfection.
Supplemental Figure S2 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

Correlation between the expression level of ADAR1 and the editing level of AZIN1 (left panel) or FLNB (right panel) among nine ESCC cell lines.
Supplementary Movie 1 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

MP4 file - 1431K, Supplementary movie S1: time-lapse video-microscopy with a 10x magnification objective, of Mel501 cells plated on plastic 48 hr after MOCK transfection.
Supplemental Figure S1 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

The relative ADAR1 expression level in nine ESCC cell lines, as detected by QPCR.
Supplementary Figure 7 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 67K, (A) Heatmap representation of ICAT/CTNNBIP1 levels and unsupervised hierarchical clustering based on transcriptomic analysis of ICAT/CTNNBIP1 expression in 22 human melanoma metastases (31). (B) Significant decrease of median Distant Metastasis Free Survival (DMFS) time in cluster 1 (8 metastasis with high ICAT/CTNNBIP1 expression) compared to cluster 2 (14 metastases with intermediate to low ICAT/CTNNBIP1 expression). (C) Correlating NEDD9 mRNA expression levels with the expression ratio of b-catenin/ICAT shows a positive trend in metastatic melanoma (Jonsson et al., 2010). Note that tumors belonging to cluster 1 are in red and tumors belonging to cluster 2 are in green. *p<0.01
Supplementary Figure 3 from Activation of the Glutamate Receptor GRM1 Enhances Angiogenic Signaling to Drive Melanoma Progression
Authors: Wen Yu , Li Jiadong , Koo Jasmine , Shin Seung-Shick , Lin Yong , Jeong Byeong-Seon , Mehnert Janice M. , Chen Suzie , Cohen-Sola Karine A. , Goydos James S.
Published: March 2023

PDF file - 237KB, Supplemental Figure 3: Stable GRM1 knock-down cells lines were obtained by shRNA. 50% GRM1 protein level decrease in UACC9093-G4 cells dramatically decreased VEGF secretion, but 50% GRM1 protein level decrease in UACC903-G2 was not sufficient to decrease IL8 secretion to lower than that of untreated UACC903-G4.
Supplementary Figure 1 from Activation of the Glutamate Receptor GRM1 Enhances Angiogenic Signaling to Drive Melanoma Progression
Authors: Wen Yu , Li Jiadong , Koo Jasmine , Shin Seung-Shick , Lin Yong , Jeong Byeong-Seon , Mehnert Janice M. , Chen Suzie , Cohen-Sola Karine A. , Goydos James S.
Published: March 2023

PDF file - 737KB, Supplemental Figure 1: Apoptosis antibody array result of Uacc903-V1 and -G2.
Supplementary Figure 3 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 114K, ICAT DQE mutant does not bind to b-catenin.
Supplementary Figure 2 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 117K, Transient exogenous ICAT expression does not affect the proliferation rates and the viability of Lu1205, Mel501 and Skmel3 cells.
Supplementary Figure S3 from Distinct Functions of Epidermal and Myeloid-Derived VEGF-A in Skin Tumorigenesis Mediated by HPV8
Authors: Ding Xiaolei , Lucas Tina , Marcuzzi Gian P. , Pfister Herbert , Eming Sabine A.
Published: March 2023

Supplementary Figure S3. FACS sorted keratinocytes.
Supplementary Figure S1 from Distinct Functions of Epidermal and Myeloid-Derived VEGF-A in Skin Tumorigenesis Mediated by HPV8
Authors: Ding Xiaolei , Lucas Tina , Marcuzzi Gian P. , Pfister Herbert , Eming Sabine A.
Published: March 2023

Supplementary Figure S1. Myeloid cell-restricted VEGF shows no impact on immune cell recruitment during early stage wound-induced papilloma formation in HPV8 mice.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure 4: Accelerated tumor development in Hpa-Tg mice exposed to DMBA/TPA skin carcinogenesis treatment.
Supplementary Figure 8 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

PDF file - 1486K, Figure. S8. Treatment with ASC-J9 could inhibit RCC cells migration, invasion and proliferation.
Supplementary Figure 7 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

PDF file - 3303K, Figure. S7. blocking AR signaling could inhibit AR positive cell migration, invasion and proliferation in a concentration-dependent in vivo and in vitro.
Supplementary Figure 5 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

PDF file - 471K, Figure. S5. AR suppresses the expression of Hif-2αand VEGF via could miR-145.
Supplementary Figure 4 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

PDF file - 271K, Figure. S4. HIF2a promoter luciferase assay also demonstrated that AR could modulate the transcription of HIF-2α in RCC cells.
Supplementary Video 2 from miR-28-5p Promotes Chromosomal Instability in VHL-Associated Cancers by Inhibiting Mad2 Translation
Authors: Hell Michael P. , Thoma Claudio R. , Fankhauser Niklaus , Christinat Yann , Weber Thomas C. , Krek Wilhelm
Published: March 2023

MOV file - 714KB, Suppl. Movie 2: Analysis of nocodazole-induced mitotic arrest in HeLa cells expressing miR-28-5p. Time-lapse (5 min interval, total time: 14h) movies of nocodazole-arrested HeLa H2B-GFP cells transfected with miR-28-5p.
Supplementary Figure 3 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

PDF file - 1477K, Figure. S3. RCC cell proliferative ability were determined by BrdU incorporation assay.
Supplementary FIgure S5 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

Figure. S5. AR suppresses the expression of Hif-2αand VEGF via could miR-145.
Supplementary FIgure S4 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: March 2023

Figure. S4. HIF2a promoter luciferase assay also demonstrated that AR could modulate the transcription of HIF-2α in RCC cells.
Supplementary Figure 1 from Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma
Authors: Guest Rachel V. , Boulter Luke , Kendall Timothy J. , Minnis-Lyons Sarah E. , Walker Robert , Wigmore Stephen J. , Sansom Owen J. , Forbes Stuart J.
Published: March 2023

PDF file - 222K, Supplementary Figure 1. ICC can arise from mature biliary epithelia.
Supplementary Table 1 from CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
Authors: Lau Wen Min , Teng Eileen , Chong Hui Shan , Lopez Kirsten Anne Pagaduan , Tay Amy Yuh Ling , Salto-Tellez Manuel , Shabbir Asim , So Jimmy Bok Yan , Chan Shing Leng
Published: March 2023

PDF file - 20KB, Supplementary Table S1 shows patient clinical information.
Supplementary Figure 3 from IL-17A Produced by γδ T Cells Promotes Tumor Growth in Hepatocellular Carcinoma
Authors: Ma Shoubao , Cheng Qiao , Cai Yifeng , Gong Huanle , Wu Yan , Yu Xiao , Shi Liyun , Wu Depei , Dong Chen , Liu Haiyan
Published: March 2023

PDF file - 128KB, Tumor growth is reduced in TCRdelta-/- mice.
Supplementary Figure 2 from IL-17A Produced by γδ T Cells Promotes Tumor Growth in Hepatocellular Carcinoma
Authors: Ma Shoubao , Cheng Qiao , Cai Yifeng , Gong Huanle , Wu Yan , Yu Xiao , Shi Liyun , Wu Depei , Dong Chen , Liu Haiyan
Published: March 2023

PDF file - 63KB, IL-17A production by different cell subsets in the tumor microenvironment.
Supplementary Methods from A Sequence Polymorphism in miR-608 Predicts Recurrence after Radiotherapy for Nasopharyngeal Carcinoma
Authors: Zheng Jian , Deng Jieqiong , Xiao Mang , Yang Lei , Zhang Liyuan , You Yonghe , Hu Min , Li Na , Wu Hongchun , Li Wei , Lu Jiachun , Zhou Yifeng
Published: March 2023

PDF file - 173K, Additional experimental information including radiotherapy, plasmids, lentiviral production, and transduction data. Also includes RNA extraction and microarray analysis, quantitative RT-PCR analysis, and animal model.
Supplementary Figures 1 - 5, Table 1 from The Niacin/Butyrate Receptor GPR109A Suppresses Mammary Tumorigenesis by Inhibiting Cell Survival
Authors: Elangovan Selvakumar , Pathania Rajneesh , Ramachandran Sabarish , Ananth Sudha , Padia Ravi N. , Lan Ling , Singh Nagendra , Martin Pamela M. , Hawthorn Lesleyann , Prasad Puttur D. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: March 2023

PDF file - 548K, Supplementary Table S1- Primers used for the RT-PCR assays. Figure S1. DNA methylation inhibitor re-activates GPR109A expression in human breast cancer cells. Figure S2. Stable expression of GPR109A in human breast cancer cell lines. Figure S3. GPR109A activation in breast cancer cells inhibits anti-apoptotic genes and induces pro-apoptotic genes. Figure S4. GPR109A activation in breast cancer cells regulates genes involved in various cellular processes. Figure S5. GPR109A binding is inhibited by components in the media. A, MB231-pCDH and MB231-GPR109A stable cell lines were subjected to radio-labeled nicotinate (NA) binding with binding buffer and L15 media.
Supplementary Figure 4 from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 116KB, TGF-alpha is not a critical ligand for DCA-induced EGFR signaling.
Supplementary Figure S2 from 5-Lipoxygenase Is a Candidate Target for Therapeutic Management of Stem Cell–like Cells in Acute Myeloid Leukemia
Authors: Roos Jessica , Oancea Claudia , Heinssmann Maria , Khan Dilawar , Held Hannelore , Kahnt Astrid S. , Capelo Ricardo , la Buscató Estel , Proschak Ewgenij , Puccetti Elena , Steinhilber Dieter , Fleming Ingrid , Maier Thorsten J. , Ruthardt Martin
Published: March 2023

Effect of sEH-/- on replating efficiency of PML/RARα-expressing HSPCs.