bluuebunny/crossref_metadata_2025 huggingface dataset:
Тенденції розвитку архітектури міста Ковель в міжвоєнний період
Authors: Абрамюк Інна Георгіївна
Published: August 2022

Мета підготовки матеріалу виникла із необхідності комплексного вивчення тенденцій формування архітектури волинського міста Ковель, як прикладу архітектурно-просторового розвитку малих міст, у 20-30-тих роках ХХ ст. Будучи у 20-30-тих роках ХХ ст. важливим транспортним та військово-адміністративним центром, Ковель, незважаючи на статус малого міста, привертав увагу як соціокультурний осередок, архітектурний розвиток якого характеризувався багатовекторністю та орієнтованістю на комфорт мешканців. Досягнення мети проведеного дослідження відбувалося шляхом опрацювання та аналізу архівних джерел, іконографічних й картографічних матеріалів, наукових публікацій та періодики. В першу чергу, з’ясовано основні засади і принципи вирішення архітектури житлових будівель, ансамблів, кварталів, за допомогою комплексної методики стилістичного та композиційного аналізів. Що в свою чергу, уможливило, визначення стилістичних традицій, котрі використовувались архітекторами на теренах Ковеля впродовж міжвоєнного двадцятиліття.Широке коло науковців в сферах історії, історії архітектури та урбаністики, соціології висвітлювали аспекти історичного розвитку Ковеля, коментуючи архівні документи. Зокрема, свою увагу питанню приділяли П.Ричков, О.Михайлишин, С.Лінда, А.Заяц, А.Боровік та ін. Встановлено, що з 1920 року, Ковель разом із цілою Волинню став частиною Польської держави і отримав статус повітового міста Волинського воєводства. З цього часу розпочався активний розвиток міської архітектури, котра стала символом сучасності поряд із просторовим розвитком міста, спрямованого на впорядкування забудови і підвищення рівня його комфорту. З’ясовано, що включення Ковеля в авангардний керунок архітектурного розвою держави відбувалося шляхом розробки проектів важливих міських об’єктів архітекторами із Варшави, Любліна та Луцька, зокрема, Стефанем Шиллером, Володимиром Вінклером, Йозефом Шанайца, Богданом Лахертом, Владиславом Стахонем та рядом інших зодчих. Виявлено, що в короткому часі двадцятилітньої історії, відбулися істотні зміни у архітектурно-просторовій структурі Ковеля, котрі відображали два глобальних стильових напрямки: традиціоналізм та авангардизм. На теренах міста з’являлися будівлі, котрі репрезентували риси «дворкової» традиційної архітектури, неоготичний стиль та поєднання неокласицизму із простими об’ємами модернізму.Подальші детальні дослідження архітектури Ковеля й її популяризація, дасть можливість зберегти спільну українсько-польську спадщину та розробити концепції розвитку міста із врахуванням цінності традицій, не руйнуючи естетичної цілісності середовища історично сформованих ареалів.
CURRICULUM MODELING: AN EXAMPLE OF ACCOUNTING CURRICULUM
Authors: Alver Jaan , Alver Lehte
Published: August 2022

The process of globalization sets up new requirements for the curricula building in the business world. There is more pressure on accounting professionals to expand and enhance their knowledge, skills, and abilities beyond what they are currently likely to possess. Providers of accounting education must take into account the changed world and create contemporary curricula. The paper explains a new model of accounting curriculum developed at Tallinn University of Technology as well as its educational philosophy and principles of designing. It also describes conditions required for development and continuous improvement of competitive curriculum.
Peripheral Blood Expressions of MicroRNA-146a and MicroRNA-218 in Chronic Obstructive Pulmonary Disease with/without Cigarette Smoke Exposure
Authors: Nadi Ebrahim , Geramirad Ghazal , Kahramfar Zohreh , Rasouli-Saravani Ashkan , Solgi Ghasem
Published: August 2022

Altered expression and dysregulation of microRNAs (miRNAs) have been reported in different samples of chronic obstructive pulmonary disease (COPD) patients. The present study attempted to evaluate the peripheral expressions of miR-146a and miR-218 in COPD patients and sex-matched healthy controls with/without cigarette smoke exposure (CSE).
In this case-control study, blood samples were collected from 60 COPD patients (30 with CSE and 30 non-CSE in each group) and 60 healthy controls. Peripheral expressions of miRNA-146a and miR-218a were measured using qRT-PCR and results were compared between cases and controls as well as within the subgroups of patients.
We found significantly decreased expressions for both miRNAs in the patients compared to healthy controls. Remarkable underexpression of miRNA-146a and miRNA-218 were found in the CSE and non-CSE patients compared to non-CSE healthy controls and even in the CSE versus non-CSE controls. Both groups of patients showed underexpression of two miRNAs in comparison with CSE healthy controls and interestingly, similar decrements were observed in the CSE versus non-CSE patients. Also, ROC curve analysis revealed the significantly diagnostic powers for both miRNAs in discrimination of patients from healthy individuals and CSE-COPD from non-CSE COPD patients.
The underexpression of miR-146a and miR-218 in COPD patients and relation to CSE can be indicative of CSE-induced changes in miRNA expression profile and potential for these biomarkers in COPD risk assessment, particularly in those patients with CSE.
Levofloxacin versus ceftriaxone and azithromycin for treating community-acquired pneumonia: a randomized clinical trial study
Authors: Yadegarynia Davood , Tehrani Shabnam , Maghsoudi Nejad Fatemeh , Shojaeian Fatemeh , Keyvanfar Amirreza
Published: August 2022

Background and Objectives: We compared two common antibiotic regimens for the treatment of mild to moderate CAP: levofloxacin versus β-lactam and macrolide combination; in terms of their efficacy and side effects.
Materials and Methods: Patients with mild to moderate CAP were randomized into two groups. Group I received a combi- nation of 1 gram ceftriaxone daily and 500 mg azithromycin daily for 5-7 days. Group II received levofloxacin 750 mg daily for five days. The signs and symptoms, hospitalization length, and the side effects were investigated.
Results: There were 77 and 74 patients in groups I and II. The vital signs of group II were significantly better on the 3rd day of admission, except for the temperature (P=0.09). The O saturation of group II was markedly improved on the 5th  day of admission (P=0.0061). In terms of clinical symptoms and hospitalization length, group II was considerably better. However, the rate of side effects in both groups was similar (P=0.885).
Conclusion: Hospitalized patients with mild to moderate CAP might take more advantage of fluoroquinolone administra- tion. It could improve the patients' signs and symptoms and reduce hospitalization length, compared with the combination of macrolide and cephalosporin, with the same rate of side effects.
Investigation the effects of silver nanoparticles and gold nanoparticles on expression of bap and csu genes in biofilm formation of Acinetobacter baumannii
Authors: Rezania Niloofar , Rahmati Parisa , Noorbakhsh Fatemeh , Farhadyar Nazanin , Lotfali Ensieh
Published: August 2022

Background and Objectives: Acinetobacter baumannii is one of the main pathogens of the hospital and causes various in- fections. csu A/BABCDE involved in the initial surface attachment during biofilm formation and bap gene produces specific proteins at the cell surface that play a direct role in formation of biofilm and the infectivity of this bacterium. The aim of this study was to investigate the effect of silver nanoparticles and gold nanoparticles on the expression of bap and csu genes in the Acinetobacter baumannii biofilm formation.
Materials and Methods: The susceptibility test was performed to determine the MIC of silver nanoparticles, gold nanoparti- cles and gold- vancomycin nanoparticles performed by broth dilution method on A. baumannii strains. The ability of biofilms formation in strains treated by MIC of silver nanoparticles and gold- vancomycin nanoparticles were evaluated by microtiter plate method and A. baumannii ATCC19606 used as control. Expression of the csu and bap genes were determinded by measuring the cognate mRNA level by real-time PCR.
Results: In present study, gold nanoparticles could not prevent the growth and biofilm formation of A. baumannii strains. The MIC concentration of silver nanoparticles and vancomycin- gold nanoparticles were 6.25 μg/ml  and 0.625 μg/ml re- spectively and MBC concenteration of nanoparticles for 70% of strain was 12.5 μg/ml and 1.25 μg/ml respectively. Real-time PCR and data analysis, determined that the expression of bap, csuC and csuE genes in A. baumannii strains treated with MIC concentration (6.25 μg/ml)  of silver nanoparticles decreased compared to control groups. Also, the expression of csuC and csuE genes in strains treated with MIC concentration (0.625 μg/ml) of vancomycin -gold nanoparticles increased, however the expression of bap was decreased compared to the control groups.
Conclusion: Due to the inhibitory effect of silver nanoparticles and gold- vancomycin nanoparticles against A. baumannii biofilm formation and genes expression, they can probably be used for prevent of biofilm formation  in medical instrument or can be use  for treatment of infections with or without antibiotic.
No quintal do PIBID, os achadouros docentes: casos de ensino, narrativas formativas e desenvolvimento profissional
Authors: Sousa Sandra Novais , Nogueira Eliane Greice Davanço , Rocha Cristiane Ribeiro Cabral
Published: August 2022

O artigo objetiva trazer ao debate as interfaces entre os casos de ensino e as narrativas formativas, tomando como objeto de análise as ações desenvolvidas em um subprojeto do Programa de Bolsa de Iniciação à Docência (Pibid), no âmbito do curso de Pedagogia da Universidade Estadual de Mato Grosso do Sul. Como procedimentos metodológicos, tendo como referencial teórico o método biográfico, foi realizado um levantamento bibliográfico da produção sobre o Pibid, a pesquisa narrativa e os casos de ensino, além da análise de relatórios produzidos por participantes do subprojeto no período de 2011 a 2017 e a produção de um caso de ensino a partir de observações das aulas de uma professora iniciante egressa do Pibid e entrevistas à professora e à gestora da escola em que atuava. Os resultados apontaram que os casos de ensino se situam, metodologicamente, no campo das narrativas formativas, histórias de vida, memoriais, narrativas autobiográficas e outros dispositivos ligados à pesquisa narrativa e ao método biográfico. Concluímos que a utilização de casos de ensino no referido subprojeto propiciou aos participantes do Pibid a reflexão sobre as práticas docentes, o espaço escolar e as concepções sobre ensino, aprendizagem e profissão docente, qualificando a formação inicial e potencializando a instituição de práticas alfabetizadoras pautadas no uso social da leitura e da escrita e na ludicidade.
Uma experiência de uso do método de casos em formação continuada de professores
Authors: Esteves Maria Manuela Franco
Published: August 2022

O uso do método de casos na formação continuada de professores é especialmente relevante na medida em que lhes pode permitir evocar e narrar situações reais de trabalho, partilhar a sua narrativa com os restantes colegas em formação e com os formadores, refletir coletivamente sobre cada caso e sobre o conjunto de casos em análise. Visa-se com este artigo descrever uma experiência de formação continuada de professores (dois por cada escola ou agrupamento de escolas) investidos da missão de passarem a constituir a secção de formação e monitorização de um dado centro de formação inter-escolas. Dentro da estratégia de formação que foi delineada, o uso do método de casos teve lugar na fase inicial do projeto que deveria concluir-se pela produção, pelos participantes, de planos de formação docente, devidamente contextualizados, a integrar no projeto educativo de cada escola. O projeto desenvolvido inspirou-se nos modelos de formação personalista e orientado para a pesquisa, tal como Zeichner (1983) os define e radicou no conhecimento científico acumulado acerca do uso do método dos casos na formação de professores. Para além do valor produtivo que o uso do método de casos teve, será posto em evidência o seu valor formativo para a constituição e a dinâmica de um grupo de formandos que não se conheciam à partida e entre os importava que se desenvolvesse a confiança, a colaboração, a capacidade de formação interpares e a reflexividade.
Educação escolar em tempos de pandemia: direito à educação, ensino remoto e desigualdade social
Authors: Rogrigues Cesar Augusto
Published: August 2022

O artigo discute o tema da inclusão/exclusão no campo da educação escolar enfatizando as políticas públicas, sobretudo as elaboradas durante a pandemia do novo coronavírus (Covid-19). Entre essas, destaca-se o ensino remoto como alternativa mais comum das Secretarias Estaduais de Educação visando garantir o direito à educação. Contudo, a partir da análise das políticas públicas adotadas pela Secretaria da Educação do Estado de São Paulo em 2020, em especial durante o período de pandemia, verifica-se que, além de insuficientes na garantia do direito à educação de maneira igualitária, tais políticas acabam por reforçar ainda mais a desigualdade social intrínseca ao sistema capitalista. Com base na abordagem histórico-cultural, analisam-se as limitações e contradições envolvendo o ensino remoto, evidenciando a maneira pela qual essa alternativa, não por acaso, está diretamente ligada ao processo de aprofundamento da precarização das políticas públicas educacionais a partir da crise econômico-política brasileira dos últimos anos e que se expressa agora de maneira contundente em meio à crise sanitária determinada pela pandemia. Conclui-se que a luta cotidiana por ampliação do direito à educação deve ser a mediação de um projeto de inclusão para além do capital.
Comparison of Intraoperative and Postoperative Outcomes of Proximal Femoral Nailing and Bipolar Hemiarthroplasty Techniques in Intertrochanteric Femur Fracture Treatment
Authors: YETİŞ Mehmet , YURDAKUL Emre
Published: August 2022

Aim: This study was undertaken with the purpose of comparing the short and long term surgical, clinical, and functional results between bipolar hemiarthroplasty and proximal femoral nailing in the same cohort of patients.
Material and Methods: The retrospective scanning of two-year data of a tertiary care hospital has been carried out for patients with hip fractures undergoing proximal femoral nailing and bipolar hemiarthroplasty. 67 patients underwent proximal femoral nailing and 74 patients underwent bipolar hemiarthroplasty were included in the study. Each patient's short and long term outcomes were documented as well as their preoperative, intraoperative, and postoperative features.
Results: There were no significant differences in the demographic features of both groups. The median intraoperative blood loss was significantly higher in the group who underwent bipolar hemiarthroplasty compared to the group who underwent proximal femoral nailing (450 cc vs 300 cc, respectively, p<0.001). It was found that the bipolar hemiarthroplasty procedure was associated with a greater need for intraoperative transfusion than the proximal femoral nailing procedure (p=0.007). Intraoperative complications were reported only in patients who underwent bipolar hemiarthroplasty. The need for intensive care unit was significantly higher in the bipolar hemiarthroplasty group than in the proximal femoral nailing group, with the rate of 86.5% (n=64) and 68.7% (n=46), respectively (p=0.011).
Conclusion: According to the results of this study, the proximal femoral nailing procedure appears to be a more reliable surgical technique in patients with hip fractures in terms of both intraoperative complications and the postoperative need for an intensive care unit.
Comparison of the Effect of Board Game and Tobacco Cessation Education on Nicotine Addiction in Adolescent Smokers
Authors: CAN Remziye , ÖRSAL Özlem
Published: August 2022

Aim: The aim of this study was to compare the effect of a board game and tobacco cessation education on nicotine addiction in adolescent smokers.
Material and Methods: This randomized controlled study included 103 adolescents who declared to smoke at least one cigarette per day. For data collection, sociodemographic data form, Fagerstrom test for nicotine dependence, and stages of change scale were used. The study groups consisted of three intervention groups; board game, tobacco cessation education, and the combined use of these two interventions, and a control group. All interventions were compared with the control group. Follow-ups were conducted at baseline, 8th, and 12th week.
Results: While 38.8% (n=40) of all participants were addicted to nicotine at a very low level, 6.8% (n=7) were very high. 37.9% (n=39) of the participants reported smoking the first cigarette of the day within the first 5 minutes. Groups had an effect on the nicotine addiction level of adolescents (p=0.031), while there was no significant difference for the period, and period*group interaction (p=0.472 and p=0.339, respectively). The difference was due to the board game group. In the post evaluation, three of the adolescents who played board games and two of the adolescents who received tobacco cessation training were in the action phase.
Conclusion: The results showed that the board game group participants had a decrease in the level of nicotine addiction. Our suggestion is to use and disseminate games as an alternative method that will attract the attention of adolescents in tobacco cessation education.
The Anticoccidial Effects of the Poultry Bile against Eimeria papillata Oocysts of Mice: In vitro Study
Authors: Murshed M. , Al-Quraishy S. , Qasem M.A.
Published: August 2022

Background: Coccidiosis is a costly and wide-spread infectious disease in mammals that causes huge losses in the poultry industry worldwide. The present study was conducted to evaluate the potency of intact poultry gallbladder on the sporulation of Eimeria papillata oocysts of mice and to determine the best concentration for the activity of poultry bile on the inhibition of sporulation in oocysts. Methods: In this test, we used potassium dichromate solution (2.5%) as control group. Unpopulated oocysts were exposed (1 x 103/3 ml) to four concentrations of poultry bile (w/v; 10%, 25%, 50%, and 100%). It was incubated in petri dishes for 48, 72 and 96 hours at 25-29°C, with 60-80% humidity. The sporulation was examined under an inverted microscope at 40 x to confirm oocyst sporulation. Result: Showed through infrared spectroscopy of poultry bile that there are many expected active classes of chemical compounds. At a 100% concentration of poultry bile, it was able to inhibit the Eimeria papillata oocysts by about 98% in potassium dichromate solution. Also, it observed its ability to inhibit sporulation of oocysts in a dose-dependent manner at concentrations of 50%, 25%, and 10% of bile, the rate of inhibition was (71.7%, 33.11% and 19.88%), respectively. We found a direct relationship between inhibition and sporulation related to the increasing time period.
Therapeutic Landscapes For Immigrant Latina Survivors of Intimate Partner Violence
Authors: Terrazas-Carrillo Elizabeth , Garcia Ediza , Malagon Adriana , Gonzalez Mitzy
Published: August 2022

The purpose of this study was to identify the therapeutic landscapes of immigrant Latina survivors of intimate partner violence (IPV). The rate of IPV among Latinas is alarming and research has documented the effects of IPV on the survivor’s mental health. Immigrant Latina women possess vulnerability factors that compound their ability to receive treatment. Notably, therapeutic landscapes serve to foster recovery yet research has not identified these places for immigrant Latinas. Our qualitative study aimed to fill this gap. Our findings include four themes: Places of worship, places of social support, places of empowerment, places of freedom. Implications for practice within a cultural context are discussed.
Valorization of Garlic Peel as a Potential Ingredient for the Development of ValueAdded Rice Based Snack Product Pukhelein
Authors: Lyngdoh Jesparwell , Ray Subhajit
Published: August 2022

The present study was designed to develop and evaluate the nutritional, functional, sensory properties and texture profile data of garlic peel powder fortified viz. 2%, 5% and 10% value added pukhelein and compared with control sample. Garlic peel showed crude fiber, carbohydrate and ash content viz. 60.57%, 21.71% and 16.34%, total phenolic content (TPC) of 108.79 µg/ml GAE, total flavonoid content (TFC) of 33.27 mg Quercetin/ml and antioxidant activity (33.38 mg/ml) respectively. 5% formulation exhibited the highest crude fiber, protein content, TPC (326.6 µg/ml GAE), TFC (91.38 mg Quercetin/ml) and total antioxidant content (54.68 µg/ml).Sensory evaluation data showed good result in 5% formulation in terms of appearance, texture and taste. Texture profile analysis showed that a considerable decrease in hardness, springiness, cohesiveness, gumminess and chewiness and resilience. The outcome of the study revealed that 5% garlic peel powder fortified pukhelein exhibited the best result among all formulations.
The Influence of Working Capital Management on the Profitability of Listed Manufacturing Companies in Tanzania
Authors: Kisyeri Dickson Matiko , Kira Alex Reuben
Published: August 2022

Working capital management (WCM) and listed manufacturing companies (LMCs) profitability are subjects that have taken much attention of scholars globally because cash management, inventory management, receivables, and payables management components are vital elements for the performance of businesses. However, there is limited literature on the subject that considered the DuPont analysis as a measure of LMCs’ profitability as well as that used the finite distributed lag model to analyze WCM variables and profitability. Likewise, there is patchy recorded literature so far that tried to use administration expenses and marketing expenses to moderate the relationship between WCM and LMCs’ profitability. To bridge this knowledge gap, this study investigated the influence of WCM on profitability of LMCs’ on the Dar es Salaam Stock Exchange Plc (DSE), Tanzania. The study used an explanatory research design based on objectivism philosophies whereby profitability data were collected from the financial reports of the listed manufacturing companies on DSE. Panel data with the Finite Distribution Lag Model was used to analyze the published audited financial reports for 14 years, from 2005 to 2018 inclusive, of listed manufacturing firms. The results showed that current year marketing and administration expenses as moderators cause a lag of three years in the average collection period and each for moderator to have a positive impact on profitability, while the current year average collection period had a negative impact on profitability. It is, therefore, recommended that LMCs in Tanzania should consider the previous three years’ average collection period, administration expenses, marketing expenses, and effectiveness in managing working capital to enhance their profitability.
Old River, Mississippi River, Atchafalaya River, and Red River (OMAR) system technical assessment : main report
Authors: Lewis James , Ashley Jonathan , Lauth Timothy , Biedenharn David , Dahl Travis , Copeland Ronald , Savant Gaurav , Brown Gary , Leech James , Donohue Patrick , Harris Kathleen , Mayne Casey , Jones Keaton , Fertitta David , Ramirez David , Ayres Steven , Agnew Maxwell , Little Charles , Dunbar Joseph , Lucker Samantha , Torres Nalini
Published: August 2022

This is the main report of Old River, Mississippi River, Atchafalaya River, and Red River (OMAR) Technical Assessment. The primary objective of the OMAR Technical Assessment was to conduct a comprehensive evaluation that aimed to understand the impacts of former and potential changes to the system in the vicinity of the Old River Control Complex (ORCC) over time, the water and sediment delivery regime at the ORCC, and the effects to the river system surrounding the ORCC. Scenarios evaluated in this technical assessment were designed to investigate potential system responses to a wide range of possible operational alternatives and identify knowledge gaps in current understanding of system behavior. This report summarizes and synthesizes the individual reports detailing the investigations into specific aspects of the ORCC and the surrounding region.
Silence of Rab23 inhibits hepatocellular carcinoma
Authors: LIU Si-Jia , Zang Yu-Wei , Huang Cui-Jun , liu yunjian
Published: August 2022

The authors have requested that this preprint be removed from Research Square.
Preparation and properties of phosphinic acid functionalized polyacrylonitrile hollow fiber membrane for heavy metal adsorption
Authors: Cheng Zuxin , Zhang Yuhan , Chen Kai , Xiao Kaijun , Yin Yurong
Published: August 2022

In this study, phosphorylated polyacrylonitrile hollow fiber membrane was synthesized by reacting aminated polyacrylonitrile hollow fiber membrane with phosphinic acid in a Mannich reaction. The batch single factor measurements revealed that the PPAN membrane had an outstanding ability for Hg2+ adsorption. Thermodynamic investigations indicated that the adsorption process was homogenous, and the theoretical maximum adsorption capacity predicted by the Langmuir model was 371.75 mg·g− 1. The PPAN membrane was able to successfully chelate Hg2+ ions and attain saturation in 4 hours, demonstrating that the reaction was chemically controlled by the adsorption kinetics. Based on the FT-IR and XPS spectral characterization data, successful phosphinic acid group grafting was proven, and a plausible mechanism for Hg2+ adsorption by PPAN membranes was presented. Furthermore, the five adsorption-desorption cycle experiments revealed that PPAN hollow fiber membranes had outstanding reusability, indicating a possible use for removing heavy metal ions from wastewater.
Bio-Inspired Graphene Oxide membranes for Efficient Separation of Heavy Metal Ions and Desalination of Water
Authors: Janwery Dahar , Memon Fida Hussain , Rehman Faisal , Memon Ayaz Ali , Thebo Khalid Hussain , Choi Kyung Hyun
Published: August 2022

Sufficient efforts have been carried out to fabricate highly efficient graphene oxide (GO) lamellar membranes for heavy metal ion separation and desalination of water. However, selectivity for small ions remains a major problem. Herein, GO-based bio-inspired membranes are fabricated by green method and used for selective separation of heavy metal ions and water desalination. The GO is modified with Onion extractive (OE) and fabricated into GO/OE composite membranes. The GO/OE composite membrane (350 nm) shows an excellent rejection efficiency for several heavy metal ions such as Cr6+ (~ 87.5%), As3+ (~ 89.5%), Cd2+ (~ 93.0%), Pb2+ (~ 99.5%), and good water permeance ∼460 ± 20 Lm− 2h− 1bar− 1. In addition, GO/Quercetin (GO/Q) membrane is also fabricated from quercetin for comparative studies. Quercetin is active ingredient of onion extractives. The GO/Q composite membranes show good rejection up to ~ 78.0%, ~ 80.5%, ~ 88.0% and 95.2% for Cr6+, As3+, Cd2+, and Pb2+ respectively with DI water permeance ∼150 ± 10 Lm− 2h− 1bar− 1. Further, both membranes are used for water desalination by measuring rejection of small ions such as NaCl, Na2SO2, MgCl2, and MgSO4. The resulting membranes show ˃70% rejection for small ions. In addition, both membranes use for filtration of Indus River water and GO/Q membrane shows remarkable high separation efficiency and making river water suitable for drinking purpose. Furthermore, the GO/QE composite membrane is highly stable up to ~ 25 days under acidic, basic and neutral environments as compared to GO/Q composite and pristine GO-based membranes.
Three-level hierarchical micro/nanostructures on biopolymers by injection moulding using low cost polymeric inlays
Authors: Sáez-Comet Carlos , Muntada Olga , Lozano Nekane , Fontdecaba Enric , Sousa Patricia C. , Llobet Jordi , Perez-Murano Francesc , Puiggali Jordi , Valle Luis Javier del
Published: August 2022

The industrial interest in the patterning of surfaces at the micro/nanoscale to include functionalities to a variety of objects and parts has considerably increased across a large range of application sectors during the last years. Hierarchical organization of micro/nanometric surface textures makes it possible to mimic biological solutions to provide enhanced functional properties, as for example, hydrophobicity, hydrophilicity, antibacterial activity, optical or chromatic effects, to cite some. Multiple and high accuracy methods for patterning surfaces at the nanoscale have been developed, and some of them have been applied for high volume manufacturing of such hierarchically patterned surfaces with relative success. However, many of those methodologies rely on the use of expensive machinery and moulds, or on complicated and expensive inserts. Therefore, a method using low cost recyclable tooling and process conditions applicable to high volume manufacturing is currently missing. In this work, we present a scalable, low cost method to replicate hierarchical micro/nanostructured surfaces on plastic films, which can be latter used as inlays for injection moulded parts with standard processing conditions. We use this method to demonstrate the feasibility of replicating three level hierarchical micro/nano textured surfaces using recyclable bio-based polymers (of high relevancy in the current plastic pollution context), and we compare the replication results with those obtained in polypropylene. Finally, we characterize various mechanical and wetting properties of the replicated parts to highlight the validity of the replicated micro/nano textured surfaces, regardless of the biopolymers special crystallization characteristics.
Comparative study of biochar properties and energy consumption derived from cow manure by a pilot-scale dual-function microwave and electric pyrolysis reactor
Authors: Guo Jiali , Zheng Lei , Li Zifu
Published: August 2022

This study developed a pilot-scale dual-function pyrolysis equipment that can realize microwave pyrolysis (MP) and electric pyrolysis (EP) simultaneously from a new perspective to evaluate the effects of the two pyrolysis methods on biochar properties and its energy analysis at 300-700℃ while minimizing the interference of other factors. Results showed that the different pyrolysis methods had a greater impact on biochar properties between 300 and 500℃. Under the same pyrolysis conditions, microwave pyrolysis biocharr(MPB) had higher pH, porosity, aromaticity, fuel properties, and energy density than electric pyrolysis biocharr(EPB). MPB could be produced at a temperature 100℃ lower than EPB with similar biochar characteristics (stability and energy density). The energy yields of cow manure biochar were all above 57%, indicating that pyrolysis can greatly retain the biomass energy in biochar. The results in this study can provide guidance for the future expansion of large-scale pyrolysis to produce biochar products.
Activation of renal dopaminergic system in early diabetic nephropathy
Authors: Horita Shoichiro , Watanabe Guy , Misaka Shingen , Taira Shu , Satoh Mamoru , Maejima Yuko , Shimomura Kenju , Kazama Junichiro James , Shigetomi Shuichi
Published: August 2022

Early diabetic nephropathy is typically diagnosed using the urinary albumin-to-creatinine ratio or creatinine clearance to detect renal function decline in diabetic patients. However, it is not yet fully understood how the alteration of the renal dopaminergic system occurs during early diabetic nephropathy progression, or whether the system is a predictor of renal function associated with diabetic nephropathy. Mass spectroscopy imaging of the kidneys of spontaneously diabetic torii rats, an animal model of diabetes with diabetic nephropathy, revealed clearly differing a dopamine precursor L-dihydroxyphenylalanine distributions. Furthermore, the significantly increased excretion of urinary L-dihydroxyphenylalanine-to-creatinine or urinary dopamine-to-creatinine ratios are observed before the development of microalbuminuria. The present study represents the renal dopaminergic system responses along the progression of diabetic nephropathy, and our results will facilitate understanding of the association between early diabetic nephropathy pathogenesis and the renal dopaminergic system.
Modeling and multi-objective optimization of a combined cooling, fresh water and power system for gas turbine waste heat recovery
Authors: Norani Marziye , Deymi-Dashtebayaz Mahdi , Gholizadeh Mohammad , Dadpour Daryoush
Published: August 2022

Increasing the efficiency of gas turbine cycle (GTC)-based energy systems and reducing the irreversibility of its processes is one of the challenges that researchers are considering today. The use of waste energy of GTC and inlet air cooling to it are two techniques that help to increase the efficiency of energy production of these systems while the simultaneous it use has been less considered in multiple-generation systems. In this study, a new GTC-based tri-generation system consisting of organic rankine cycle (ORC), thermoelectric generator (TEG), reverse osmosis (RO), and absorption refrigeration cycle (ARC) subsystems is presented. This system simultaneously generates electricity, freshwater, and cooling. The total cooling capacity is used in two parts: user demand and inlet air cooling to the GTC compressor. Tri-generation system was examined from three views energy, exergy and exergoeconomic. The results of the thermodynamic analysis showed that the simultaneous use of two waste heat recovery and inlet air cooling of GTC techniques in the tri-generation system reduces the exergy destruction cost rate of the system while increasing the total energy and exergy efficiencies. To improve system performance after a parametric study, a three-objective optimization was performed using the TOPSIS method. The comparison of the results of optimal and design conditions showed that the exergy destruction rate of the system has decreased in optimal conditions and the highest rate of exergy destruction, which is related to the GTC combustion chamber component, has decreased by 66.8 kW. In addition, the total capital cost rate of the system in optimal conditions was reduced by 0.33 kW compared to the design conditions. According to the optimal results, the best performance of the system is in the conditions of the compressor pressure ratio of GTC 8.795 and the turbine inlet temperature of GTC 1505 K that the system has COP 0.74, total exergy efficiency 55.51%, and total product cost rate 32.28 $/h.
Cytopathology of cutaneous and subcutaneous neoplasms in feline species: a retrospective study
Authors: Filgueira Kilder Dantas , Chalita Maria Carolina Catai , Sellera Fábio Parra , Reche-Júnior Archivaldo
Published: August 2022

It is estimated that a quarter of all feline neoplasms affect the integumentary system. Cytological examination is of admirable importance for detection of neoplasms in companion animals, being considered a simple and non-invasive method. To date, there are limited information regarding the prevalence of feline skin cancer as well as the use of cytopathology as a diagnostic tool. In this sense, the study aimed to characterize cutaneous and subcutaneous tumors in 192 cats from the archives of a private clinic in São Paulo-SP, Brazil, specialized in the care of felines. Data regarding the animal (breed definition, sex, and age group) and tumor characteristics (biological behavior, cytomorphological category of neoplasm, and cytological suggestion for neoplasm) were obtained in a five-year period. A 95% confidence interval (CI) was estimated to verify the statistical difference between the animal and tumor characteristics. The chi-square test was carried out to verify the association between the tumor biological behavior and animal variables, as well as other tumor characteristics. Most cats were mixed breed and aged 11 to 15 years. Malignant tumors were predominant. A statistical association was observed between cytomorphological category of neoplasm and biological behavior (p<0.001). Mesenchymal (24.5%) and epithelial tumors (25%) presented the highest frequency among those benign and malignant, respectively. The cytological suggestion for neoplasm was also statistically associated with biological behavior (p<0.001). The highest percentage of occurrence of benign and malignant tumors consisted of lipomas (22.9%) and sarcomas (19.3%), respectively.
PENERAPAN PENGEMBALIAN PENDAHULUAN KELEBIHAN PEMBAYARAN PAJAK PERTAMBAHAN NILAI PT. X SEBAGAI PKP BERESIKO RENDAH
Authors: Sukmawati Anisya , Yuniardi Vira Ayu
Published: August 2022

Bagi Pengusaha Kena Pajak yang sebagian besar penjualannya adalah penjualan ekspor maka akan lebih sering mengalami lebih bayar PPN. Menurut Undang-Undang PPN Pasal 9 ayat (4b) Pengusaha Kena Pajak yang melakukan kegiatan ekspor dapat mengajukan permohonan pengembalian kelebihan PPN pada setiap masa pajak. Dan perusahaan
dapat melakukan Pengembalian Pendahuluan bagi Pengusaha Kena Pajak Beresiko Rendah atas PPN yang lebih bayar dikarenakan memiliki kriteria sebagai PKP Beresiko Rendah. Penelitian ini bertujuan untuk menjelaskan penerapan dan mekanisme pengembalian pendahuluan atas kelebihan pembayaran Pajak Pertambahan Nilai pada PT. X sebagai PKP Beresiko Rendah serta mengetahui apakah sudah sesuai dengan PMK Nomor 117/PMK.03/2019. Metode analisis yang digunakan dalam penelitian ini adalah metode deskriptif dengan data sekunder dan melalui metode pengumpulan data dokumentasi dan studi kepustakaan. Berdasarkan hasil penelitian menunjukkan bahwa PT. X memenuhi syarat untuk melakukan pengembalian pendahuluan bagi PKP Beresiko Rendah dan dalam pelaksanaannya telah sesuai dengan Peraturan Menteri Keuangan Nomor 117/PMK.03/2019. Namun dikarenakan terdapat koreksi perhitungan pajak masukan sehingga menyebabkan jumlah pengembalian pendahuluan kelebihan pembayaran pajak yang dicairkan belum maksimal sesuai dengan perhitungan Wajib Pajak.
The Triage Capability of Laypersons: Retrospective Exploratory Analysis
Authors: Kopka Marvin , Feufel Markus A , Balzer Felix , Schmieding Malte L
Published: August 2022

Background

Although medical decision-making may be thought of as a task involving health professionals, many decisions, including critical health–related decisions are made by laypersons alone. Specifically, as the first step to most care episodes, it is the patient who determines whether and where to seek health care (triage). Overcautious self-assessments (ie, overtriaging) may lead to overutilization of health care facilities and overcrowded emergency departments, whereas imprudent decisions (ie, undertriaging) constitute a risk to the patient’s health. Recently, patient-facing decision support systems, commonly known as symptom checkers, have been developed to assist laypersons in these decisions.

Objective

The purpose of this study is to identify factors influencing laypersons’ ability to self-triage and their risk averseness in self-triage decisions.

Methods

We analyzed publicly available data on 91 laypersons appraising 45 short fictitious patient descriptions (case vignettes; N=4095 appraisals). Using signal detection theory and descriptive and inferential statistics, we explored whether the type of medical decision laypersons face, their confidence in their decision, and sociodemographic factors influence their triage accuracy and the type of errors they make. We distinguished between 2 decisions: whether emergency care was required (decision 1) and whether self-care was sufficient (decision 2).

Results

The accuracy of detecting emergencies (decision 1) was higher (mean 82.2%, SD 5.9%) than that of deciding whether any type of medical care is required (decision 2, mean 75.9%, SD 5.25%; t>90=8.4; P<.001; Cohen d=0.9). Sensitivity for decision 1 was lower (mean 67.5%, SD 16.4%) than its specificity (mean 89.6%, SD 8.6%) whereas sensitivity for decision 2 was higher (mean 90.5%, SD 8.3%) than its specificity (mean 46.7%, SD 15.95%). Female participants were more risk averse and overtriaged more often than male participants, but age and level of education showed no association with participants’ risk averseness. Participants’ triage accuracy was higher when they were certain about their appraisal (2114/3381, 62.5%) than when being uncertain (378/714, 52.9%). However, most errors occurred when participants were certain of their decision (1267/1603, 79%). Participants were more commonly certain of their overtriage errors (mean 80.9%, SD 23.8%) than their undertriage errors (mean 72.5%, SD 30.9%; t>89=3.7; P<.001; d=0.39).

Conclusions

Our study suggests that laypersons are overcautious in deciding whether they require medical care at all, but they miss identifying a considerable portion of emergencies. Our results further indicate that women are more risk averse than men in both types of decisions. Layperson participants made most triage errors when they were certain of their own appraisal. Thus, they might not follow or even seek advice (eg, from symptom checkers) in most instances where advice would be useful.
Strategy for Writing Scientific Research among Students in Department of Arabic
Authors: Mahbubah Latifatul , Sutaman Sutaman , Syuhadak Syuhadak
Published: August 2022

Based on the existing data and studies, it was found that the rate of college students in Indonesia finishing their study on time is below 70%. Even in some universities, the rate of college students in Indonesia finishing their study on time did not reach 65%. Conversely, the rate of finishing study of students at IAIN Madura, East Java, Indonesia was quite high, especially students of the Department of Arabic. From the results of interviews and observations, it was found that they have a special strategy in thesis writing so that they can finish the study on time. Therefore, the aim of this research was to uncover the thesis writing strategy among the students of the Department of Arabic at IAIN Madura. This research was a qualitative case study which reveals the thesis writing strategy among the students of the Department of Arabic at IAIN Madura. The results showed that the student thesis writing strategy consisted of six strategies, namely: planning, data collection, content preparation, translation, evaluation, and revision.
HASIL BELAJAR SISWA KELAS VD MDI MUHAMMADIYAH 2 SEI KINDAUNG DENGANMENGGUNAKAN STRATEGI PEMBELAJARAN PETA KONSEP
Authors: Yulianti Wiwi , Ramdiah Siti , Lagiono Lagiono
Published: August 2022

Tujuan penelitian ini yaitu (1) Meningkatkan hasil belajar siswa kelas VD MDI Muhammadiyah 2 Sei Kindaung pada Konsep Daur Air dengan menggunakan strategi pembelajaran peta konsep. (2) Meningkatkan aktivitas siswa pada ranah psikomotor dalam pembelajaran menggunakan strategi pembelajaran peta konsep. Penelitian Tindakan Kelas ini dilaksanakan pada semester genap Tahun pelajaran 2014/ 2015, yang dilaksanakan di kelas VD MDIM 2 di Banjarmasin pada materi daur air. Penelitian dilakukan dalam 2 siklus.  Pengumpulan data hasil belajar melalui pretest dan postest, sedangkan untuk data aktivitas siswa ranah psikomotor melalui lembar observasi selama proses pembelajaran. Hasil penelitian menunjukkan bahwa Hasil belajar siswa kelas V MDI  Muhammadiyah 2 Sei Kindaung pada Konsep Daur Air dengan menggunakan strategi pembelajaran peta konsep mengalami peningkatan dan tuntas secara klasikal. Pada hasil tes siklus I ketuntasan klasikal sebesar 71,43% meningkat menjadi 88,57% pada siklus II. Aktivitas siswa pada ranah psikomotor dalam pembelajaran menggunakan strategi pembelajaran peta konsep pada masing-masing aspek mengalami peningkatan yaitu pada siklus I aspek kerjasama sebesar 3,58, bertanggung jawab sebesar 3,42, dan aspek ketelitian sebesar 2,75. Pada siklus II menjadi sebesar 4,00 pada aspek kerjasama, 3,92 pada aspek bertanggungjawab dan sebesar 3,67 pada aspek ketelitian.
Quality Of Service pada Jaringan Multi Protocol Label Switching
Authors: Irfan Muhammad , Syafa'ah Lailis
Published: August 2022

MPLS is a work plan that was given by IETF to repair work performance of IP network. Label switching label using forwarding mechanism which has connection oriented  characteristic make this technology become routing technology for future guarantec QoS with better service level. This is  supporting using a protocol signals for TE-MPLS to maximize network performance balancing the network stressing with distribution that fixed on classes, queuing, and traffic schedule. This research is an analysis of TE-MPLS mechanism to design MPLS network with RSVP-TE daemon that is called emulator MPLS. This analysis used generating 2 different kinds of protocol traffic, UDP, and TCP. The measurement could be concluded that there was an efficience of MPLS network in group joint of protocol UDP network about 18,6 % for channel that is similar with traffic 2 KBRS, 3,4 %, 1,5 %, and 5,6 % for channel similar with traffic 4,8 and 16 KBRS for flow variation of MPLS network data increase 464,2 %, 479,5 %, 518 %, and 2638,5 % for each channel. The time that was needed for TCP protocol transmition of MPLS network showed efficiency 2,9 % and bit rate of MPLS increase about 0,66 %.
Integrasi Model Lean Sigma untuk Peningkatan Kualitas Produk
Authors: Pusporini Pregiwati , Andesta Deny
Published: August 2022

In order to develop business, the company has problems associated with waste. This research focuses on the incorporation of the concept of lean thinking and six sigma concept which is lean six sigma to improve quality. Lean six sigma tools which used in this study is Big Picture Mapping, Pareto Chart, Root Cause Analysis, Fishbone Diagram, and Failure Mode and Effect Analysis. Tools used above will support the improve stage to determine the priority of reprair. From the results found that 3 critically waste were defect, overproduction and inventory. Improve stage focus on the most critical waste issue is defect, primary process improvement method of paint, the process sequence and pre assy plug gage to measure eye reaming process. Waste overproduction and inventory focused on the Master Production Schedule (MPS). These improvements were expected to resolve issues relating to the elimination of defects, overproduction and inventory.
Analisis Kelayakan Rencana Investasi Mesin Produksi Guna Memenuhi Permintaan
Authors: Kholik Heri Mujayin
Published: August 2022

Eka Surya Makmur is a company that produce plastic bag. For couple years before, this company can't fill the customers demand because the machine capacity. Because of that, the labor working overtime, but still not optimal and effected to financial aspect significantly. That's way, need accurate analysis to minimize the failed effect and increase company income. To solve the problem, its suggest to use Prediction Method to predicted the future quantitatively based on current data. NPV (Net Present Value) is different value between current investment and reseipt net cash in future. IRR (Internal Rate of Return) is current interest level same with current cash flow or cash receipt in first investment. PI (Profitability Index) is ratio between present value proceed with present value outplay. PP (Payback Period) is payback parameter investment. The research result is that machine investment properly to conduct to avoid overtime job, and as financial aspect can increase net income. From financial prediction knew that demand increase 10% every year; NPV = Rp. 94.803.643.788; IRR = 40%; PI = 54,41 %; PP = 0,06 year (21,9 days).