bluuebunny/crossref_metadata_2025 huggingface dataset:
Pro- and anti-inflammatory cytokine profiles in Plasmodium Falciparum-infected individuals from Baiyeku, Ikorodu, Lagos, Nigeria
Authors: Okpokor O.D. , Ajibaye O. , Dakul D.A. , Asaga P. , Nwankwo I.
Published: October 2022

Available evidence indicates that the various stages of the malaria parasite life cycle elicit specific immune responses of which the relative levels of pro-inflammatory cytokines are key to disease progression, killing the parasite and mediating disease outcomes. This study investigated T-cell response in malaria. Four hundred and sixty-two participants were screened in a community survey of Plasmodium falciparum malaria in Baiyeku, Lagos, Nigeria. P. falciparum parasitaemia was determined by microscopy while the serum levels of IL-10, IFNγ and TNFα were determined by Enzyme-linked immunosorbent assay (ELISA). A total of 70 (15.2 %) participants were microscopically positive for P. falciparum of which 70% were females, 30% were males while children aged 1-17 years were 65.7%. The geometric mean parasite density (GMPD) was significantly (p=0.001) higher among females than males. The GMPD of participants <5 years of age was also significantly (p=0.001) higher than other age groups. About 46.8% of the participants were underweight (Body Mass Index, BMI < 18.5) and also had the highest parasite intensity. The TNFα, IFNγ and IL-10 levels were significantly (p< 0.05) higher in the infected than the uninfected participants. IFN-γ values were significantly (p=0.014) elevated among the symptomatic than the asymptomatic participants while there was no significant difference (P>0.053) in the levels of TNF-α and IL-10 (P>0.093) between the symptomatic and asymptomatic participants. The prevalence of P. falciparum obtained in this study area which is endemic to malaria is 15.2% suggesting a significant reduction of the disease over time due to awareness of the disease in the community. The levels of pro-inflammatory cytokines (IFN-γ and TNF-α) in this study were lower due to the down-regulatory action of the anti-inflammatory cytokines (IL-10). These findings suggest that higher levels of anti-inflammatory cytokines, especially IL-10 levels may contribute to the pathogenesis of uncomplicated malaria.
Comparative evaluation of BinaxNOW™ Malaria rapid diagnostic test, microscopy and polymerase chain reaction for Plasmodium falciparum detection among individuals suspected with malaria in Lagos, southwest Nigeria
Authors: Okangba C.C. , Funwei R.I. , Elikwu C.J. , Nwadike V.U. , Okangba K.K. , Osinowo A.O. , Tayo B. , Taiwo A.A. , Ogunsola A.O.
Published: October 2022

Malaria is a major public health problem in the tropics, especially in resource-limited settings where presumptive malaria treatment is well practised. Prompt malaria diagnosis is essential in ensuring definitive antimalarial therapy. Malaria rapid diagnostic tests (mRDTs) are a suitable option in resource-limited settings. The study evaluated and compared the diagnostic performance of BinaxNOW™ mRDT, microscopy and quantitative polymerase chain reaction (qPCR) in suspected malaria cases in Lagos, south-western Nigeria. The cross-sectional study was conducted in four Primary Health Centres and Ikorodu General Hospital in Lagos. A total of 146 suspected malaria patients aged 2 to 67years were screened between August 2013 and November 2013. Venous blood samples were collected after informed consent was obtained from participants or guardians for mRDT, thick blood film for microscopy and dried blood spots on filter paper for PCR assays. Sociodemographic information of each patient was collected with a structured case report form. The sensitivity, specificity, positive and negative predictive values, diagnostic accuracy, and kappa’s level of agreement were analysed. The level of statistical significance was set at ρ ≤ 0.05. Falciparum malaria positive rate and prevalence were temperature (56.8%) and age-dependent (42.5%). The sensitivity and specificity of mRDT and microscopy were 94.7%, 91.7% and 85.4%, 96.5% respectively. While the positive predictive value (PPV) and negative predictive (NPV) were 79.9%, 94.2% and 96.4%, 95.0%. The diagnostic accuracy and kappa’s level of agreement for mRDT and microscopy were 89.0%, 94.5% and 0.78 and 0.89, respectively. The performance of BinaxNOW™ malaria RDT was comparable with microscopy and can be used to guide malaria treatment in resource-limited settings to enhance parasite-based treatment of all suspected malaria cases when microscopy is unavailable.
Prevalence of haemoparasites and effects on blood parameters of horses in the Ashanti Region of Ghana.
Authors: Nimako-Boateng M.B. , Boakye O.D. , Bediako O.S. , Asare D.A. , Emikpe B.O.
Published: October 2022

A cross-sectional study was conducted to assess the prevalence of haemoparasites in horses and their effects on the blood parameters of horses in the Ashanti Region of Ghana from June to July 2021. A total of 26 horses were sampled. Three millilitres (3mls) of blood samples were collected from each horse from the jugular vein which was examined using a thin blood film and autoanalyzer. Data obtained was analysed descriptively using SPSS Version 21. A Chi-square test was performed, and the significance level was tested at a 5% significance level (P-value ≤ 0.05). Results showed 20 (76.9%) positive cases for blood parasites; of which 13 (65%) had Babesia caballi only, 1 (5%) with Theileria equi only, 5 (25%) with both Babesia caballi and Theileria equi, and 1 (5%) with both Babesia caballi and Trypanosoma equiperdum. Prevalence was observed to be high in the young horses (3-7 years) as well as in the local breed of horses and the male horses. There were marked effects on haematological parameters in infected horses. Concerning infected horses, haematocrit (HCT), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were low whilst the mean corpuscular volume (MCV) was high indicating macrocytic hypochromic anaemia. The difference in the effects on haematological parameters between infected and non-infected horses was not statistically significant (p>0.05). This study has established the presence of haemoparasites with Babesia caballi being the most prevalent parasite in the horses sampled in the Ashanti Region of Ghana with marked effects on haematological parameters indicating the presence of macrocytic, hypochromic anaemia.
Baseline epidemiological assessment of urinary schistosomiasis among school children in Okpoto District, Southeast Nigeria
Authors: Okoh F.N. , Akoma O.N. , Eze P.U.
Published: October 2022

This cross-sectional survey was set out to identify and describe urinary schistosomiasis and associated factors among school-aged children in a rural Okpoto District, Ebonyi State, Nigeria; given the relevance and scarce scientific information about the epidemiology of the infection in the area. Sedimentation and light microscopic methods were used to examine 180 urine samples of randomly selected school-aged children from three primary schools in the community for Schistosoma haematobium eggs. While relevant epidemiological data were collected using questionnaires, further laboratory investigations were conducted to estimate the amount of blood in the urine. The result of urine microscopy showed that 10 % of all the specimens examined were positive for S. haematobium, amongst which a prevalence of 16.7 % was recorded amongst males and 6.7 % among females. The prevalence of infection with S. haematobium was higher in the group 9-12 years (14.1 %) than in the 5-8 years age group (6.3 %); while Central School Lobasa had 6.6 %, Ukwuachi Primary School had 23.3 % and none detected among pupils from Ndieze Primary School. Results of the urine reagent strip showed 0 %, 20 % and 0 % positives in pupils from Central School Lobasa, Ukwuachi Primary School, and Ndieze Primary School, respectively. The outcome of this investigation confirmed that urine containing blood contains schistosome eggs. The related environmental, as well as host behavioural factors identified in this study, suggest that the overall prevalence of schistosomiasis in this area could be fast-increasing, with attendant morbidity and mortality implications. This effort, therefore, provides an appropriate basis for further investigation; urgent implementation and sustenance of relevant control interventions.
Contraceptive practices among women of reproductive age in Mbeya, Tanzania
Authors: Hamis Yina , Kaminyoghe Elias , Mweya Clement
Published: October 2022

Background: Non-utilisation of contraceptive contribute to unintended pregnancies and unsafe abortions, which are major public health problems in Tanzania and sub-Saharan Africa. Our study investigated contributing factors and contraceptive use practices among women of reproductive age in Mbeya, Tanzania.

Methods: A hospital-based descriptive cross-sectional study was conducted on women attending reproductive and child health clinics. Data obtained included participants’ age, education and other demographic characteristics. Awareness of family planning methods, use, attitudes, advocacy and practices were also recorded. A χ2 test was used to examine the association between selected variables. 

Results: A total of 217 respondents participated in the study, of which the majority were between the ages of 21 and 26 (mean age = 26.96, standard deviation = 1.37). The majority of the respondents, 157 (72.4%) were married with mostly 1-2 children and had a primary school education or without formal education, 155 (71.4%).  191 (88.0%) respondents had heard about at least one contraceptive for family planning. Injectable was the most known method of family planning, as reported by 158 (72.8%) participants. Awareness about family planning methods and use was significantly associated with educational level (χ2 = 43.01, p = 0.0002).

Conclusion: Our study shows awareness and willingness to use family planning methods in Mbeya. Hence, it promotes a better life for families. However, more studies are needed to thoroughly investigate the various reasons affecting some non-utilisation of family planning and how these can be addressed.
HIV seroprevalence, clinical profile and surgical outcomes among patients with acquired anorectal conditions in two referral hospitals in Mwanza, Tanzania
Authors: Mwaja Dino , Washington Leonard , Boniface Tresphory , Seni Jeremiah , Mirambo Mariam , Mahalu William , Kituuka Olivia , Chalya Phillipo
Published: October 2022

Background: HIV infection, a major health problem worldwide, has been reported to be prevalent in patients with acquired anorectal conditions. There is a paucity of prospective studies regarding acquired anorectal conditions in Tanzania. This study describes the HIV seroprevalence, clinical profile and surgical outcomes among patients with acquired anorectal conditions at Bugando Medical Centre (BMC) and Sekou-Toure Referral Regional Hospital (SRRH).

Methods: This was a cross-sectional study that was conducted among patients with acquired anorectal conditions as seen at BMC and SRRH from January 2019 to June 2019.

Results:  A total of 389 patients (M: F ratio = 1.5:1) were studied. The median age at diagnosis was 42 years. Out of 389 patients, 101(26.0%) were HIV positive. Of these, 54(53.5%) were males and 47 (46.5%) were females. Haemorrhoids were the most common acquired anorectal disease accounting for 50.9% of cases. The rate of HIV infection in this study was significantly high in patients with hemorrhoids (p< 0.001), perianal ulcers (p< 0.001), anorectal abscess (p = 0.009), perianal warts (p< 0.001) and rectal prolapse (p = 0.023). A total of 173 (44.5%) patients underwent surgical treatment for acquired anorectal conditions. Hemorrhoidectomy was the most commonly performed surgical procedure in 95(54.9%) patients. Out of 171 patients who underwent surgical treatment and outcomes evaluated, 138 were treated successfully giving an overall success rate of 80.7%.  The success rate was significantly influenced by HIV positivity (p = 0.002). Surgical site infection (SSI) was the most common postoperative complication accounting for 25.8% of cases. The rate of SSI was found to be significantly higher in HIV-positive patients than in HIV-negative patients (39.6% vs 18.5%; p-value = 0.001).

Conclusion: HIV infection is prevalent among patients with acquired anorectal conditions in our setting and influences surgical outcomes. We recommend that all patients with acquired anorectal conditions in this region should be screened for HIV infection.
An Explanatory and Confirmatory Study about The spreading of Jesus’ message based on Matthew 28:18-20 by Christian Religious Education Teachers in Batam City.
Authors: Damanik Roy , Suparti Hana , Suksmono Ari , Lestari Ana
Published: October 2022

This study aims to answer three questions, namely: 1) What is the level of implementation of the sending of Jesus disciples based on Matthew 28:18-20 among Christian Religious Education Teachers in Batam City? 2) Which dimension is the most dominant in determining the implementation of the sending of Jesus' disciples based on Matthew 28:18-20 among Christian Religious Education Teachers in Batam City? 3) Which background is the most dominant in determining the implementation of the sending of Jesus' disciples based on Matthew 28:18-20 Among Christian Religious Education Teachers in Batam City?. The teacher is a person who is entrusted by God in carrying out education and teaching in accordance with the gifts that have been given to him or her. The teacher is one of the human components in the teaching and learning process, which plays a role in efforts to form potential human resources in the field of development. They should remain faithful in implementing the purpose of being sent as disciples to make all nations become disciples of Christ or His witnesses as they carry out their vocation as teachers of Christian Religious Education. They should be supported to study further and conduct suitable relevant research. The role of Christian Religious Education teacher is a distinct and core calling in the Church today.
Photometric DIC: a unified framework for global Stereo Digital Image Correlation based on the construction of textured digital twins
Authors: Fouque Raphaël , Bouclier Robin , Passieux Jean-Charles , Périé Jean-Noël
Published: October 2022

An innovative approach allowing to rigorously address surface curvature and lighting effects in Digital Image Correlation (DIC) is proposed. We draw inspiration from the research work in Computer Vision (CV) regarding the physical modelling of a camera and adopt it to bring novel and significant capabilities for full-field measurements in experimental solid mechanics. It gives rise to a unified framework for global stereo DIC that we call Photometric DIC (PhDIC). It is based on the irradiance equation that relies on physical considerations and explicit assumptions, which stands for a clear breakthrough compared to the usual grey level conservation assumption. Most importantly, it allows to define a Digital Twin of the Region of Interest, which makes it possible to compare a model with different observations (real images taken from different viewpoints). This results in a consistent formalism throughout the framework, suitable for large-deformation and large-strain displacement measurements. The potential of PhDIC is illustrated on a real case. Multi-view images are first used to measure (or scan) the shape and albedo (sometimes called intrinsic texture) of an open-hole plate. The kinematic basis considered for the displacement measurement is associated to a Finite-Element mesh. Results for the shape and albedo measurement are compared for two completely different sets of pictures. Eventually, a large displacement of the structure is measured using a well-chosen single image.
Design of an Efficient k-Winners-Take-All Module for ASIC Design
Authors:   Department of Electronics and Electrical Engineering, Dankook University, Yong-In, Republic of Korea, Yoon Myungchul
Published: October 2022

An efficient k-Winners-Take-All (kWTA) module that selects and sorts the k largest data from multiple binary data is presented in this paper. This module is implemented by pipelining a k largest element selector and a sorting circuit, both of which operate in the bit-serial method. The module completes finding and sorting the k-largest data from N of m-bit binary data in m clock cycles. This could be used as a hardware module for the ASIC design which can be employed for any ASIC chip requiring kWTA operation of digital data. The time complexity of this module is O(N) and its delay is independent of the k value. The overall kWTA operation is completed in m cycles with an internal clock which is adjusted to the number of data. According to the simulation results, the required clock cycle time (Tclk) is 68.4 ns for 1024 of 10-bit binary numbers so that the module finishes the operation by 684 ns. Keywords—Winner-Take-All, k-Winners-Take-All circuit, Digital kWTA circuit, kWTA architecture, kWTA module.
Vedad Muharemović (2019): SAVREMENOST NACIONALIZMA / Vedad MUHAREMOVIĆ (2019): Contemporaneity of Nationalism
Authors: Žarković Tatjana
Published: October 2022

Book review of: Vedad Muharemović (2019): SAVREMENOST NACIONALIZMA (Academia Analitica, Sarajevo, 220 str.)
KONCEPCIJA „DRUŠTVA RIZIKA“ ULRICHA BECKA I NJENI DOSEZI U SOCIOLOŠKOJ TEORIJI XXI ST. / THE CONCEPCTION OF ULRICH BECKS “RISK SOCIETY” AND ITS LIMITS IN XXI CENT. SOCIOLOGICAL THEORY.
Authors: Karavdić Meho
Published: October 2022

In this paper, I present an analysis of modern society, which under the influence of indicators of modernization and globalization produces risks that affect people globally with increasing uncertainty and uncertainty. Starting from Beck’s ideas, the conceptual understanding of risk is pointed out, including the concept of contemporary world events related to the emergence of COVID-19. The historical aspects of the modernization of aid to science and technological innovation and the role of capitalism, which has its foundations in this for the purpose of maximizing profits and increasing risk, are pointed out. I explain the triangulation of the terms globality, globalism and globalization and their connection with neoliberal ideology. Te wants to show how such processes have made it difficult to control and respond to COVID-19.
UGO FOSCOLO IZMEĐU NEOKLASICIZMA I PREDROMATNIZMA / UGO FOSCOLO BETWEEN NEOCLASSICISM AND PREROMANTISM
Authors: Mejdanija Mirza
Published: October 2022

By the end of the 18th century, Italy was under Napoleon’s dominance. It was the time when centuries-long European values were being changed due to the Industrial, but also French revolution. The outcome of these enormous changes was an emergence of two artistic movements – neoclassicism and preromanticism that co-existed in Italy at the time. The most renowned Italian author of the 19th century, Ugo Foscolo, is a representative of both of these movements in the Italian literature. Neoclassicism and preromanticism emerged in the attempt to find an alternative to the same issues and, therefore, they co existed in the same period of time, the elements of which are often present in the same authors, or even in one work of art. Foscolo is the author of Grazie, a neoclassical masterpiece of Italian literature, but also of the most significant work of the Italian preromanticism, the novel titled The Last Letters of Jacopo Ortis. Both of these works present an attempt to escape the disappointing circumstances of the period in question. What is relevant is not the different directions at which these attempts of escapism were pointed, but the very need to do so. Culturally, in both cases, the rejection of the reality is evident. Both tendencies may be observed as a quest for an alternative to the existing conditions that are depressing: for neoclassicism, the alternative is found in the ideal of beauty and harmony, distant from the historical horrors and defeats. For preromanticism, it is the depths of one’s own self, in the union with nature, pastorally viewed as the centre of life’s authenticity. The different directions of escapism are no longer of any importance, but the very need to escape, which is what these two movements have in common. What we are about to explore in the present paper are the characteristics of neoclassicism and preromanticism in Italian literature, primarily in the works of Ugo Foscolo, the most influential Italian author of that period.
Digital transformation of AIC: problems and solutions
Authors:   Shakarim University, Semey, Kazakhstan, Abylkassimova Zh. A. , Baizholova R. A. ,   L.N. Gumilyov Eurasian National University, Astana, Kazakhstan, Amangeldiyeva Zh. A. ,   L.N. Gumilyov Eurasian National University, Astana, Kazakhstan
Published: October 2022

An inefficient information environment in agricultural sector causes an increase in production costs, which, in turn, reduces the level of financial affordability of food products and competitiveness of agricultural products compared to foreign counterparts. The goal is to determine the role of digitalization in functioning of AIC and realization of its potential. Methods – economic-statistical, systematic approach, comparative analysis. Results – the main trends of digital transformation in agro-industrial production are considered. The goals and objectives of the state programs "Digital Kazakhstan" and development of agro -industrial complex of the Republic of Kazakhstan for 2017-2021 are shown. Prerequisites for the introduction of digital technologies in agriculture and their advantages are identified. An analysis of the use of information and comm unication systems in domestic enterprises is carried out. Relevant problems of modernizing agr icultural sector and factors hindering the formatio n of digital infrastructure of the industry, the i mportance of public-private partnerships in the development of projects based on digital processes are justified. Conclusions – the use of elements of digital economy by business entities contri butes to the preservation and enhancement of agribusiness, rational use of natural resources. The main directions of digitalization of AIC, focused on increasing the volume of produced and e xported products on the basis of improving the information array of data. The world experience of countries with a developed agricultural sector shows that distribution of IT platforms, using inn ovative software, contributes to the adoption of optimal decisions in the speedy overcoming of technological backwardness, reducing import dependence on a number of product positions, shortage of personnel with digital competencies, cost compensation and high profits.
Means of collective protection as a basis for reducing industrial injuries in the Republic of Kazakhstan
Authors:   A. Baitursynov Kostanay regional university, Kostanay, Kazakhstan, Koval A.
Published: October 2022

The goal is to present the materials obtained during the implementation of the scientific and technical program, to carry out scientific research on the topic: “Risk-oriented organizational and economic mechanisms for ensuring safe work in the conditions of modern Kazakhstan” (IRHOR11865833-OT-21) within the framework of program-targeted financing of the developments of the Republican Research Institute for Labor Protection of the MLSPP RK. Methods – overview of legislative and regulatory regulation is presented and analysis of scientific sources is carried out on composition, classification of enterprise costs, including in agro-industrial complex, means of collective protection of workers from harmful and dangerous production factors. Results – the author notes that in the Republic of Kazakhstan these aspects are practically not regulated in the safety system at production facilities, including agricultural sector, there are only general references in the current version of the Labor Law without further detail at the level of regulatory legal acts. This fact and the lack of unified approaches allow businesses to save on purchase of expensive equipment, which leads to increase in occupational injuries. An enlarged grouping of 20 classes of collective protection equipment has been carried out. Possible alternatives to the use of analytically calculated and normative methods for justification of the necessary costs are analyzed. Methodology, including basic coefficients, penalty and bonus indices, depending on the facts of injury has been developed. Conclusions – the proposed methodological provisions, after experimental testing at agro-industrial enterprises, can be submitted for legislative approval, which will ensure the effectiveness of state control of minimum labor costs for the design, implementation, operation and maintenance of relevant means of collective protection in agriculture.
Discrimination and Exclusion in Higher Education Is Reflected in Multiple Autoethnographies
Authors: Edwards Jane
Published: October 2022

A synthesis review of 17 autoethnographic (AE) studies revealed experiences of 33 academic staff and graduate students in higher education, the majority of whom are women. These papers, from more than six countries, were found through a Google Scholar search. Most authors identified as marginalised and outsiders in their higher education contexts, whether because of gender, ethnicity, race, or intersectionality. Analysis of tacit and explicit themes in the papers resulted in creation of eight final superordinate themes. The themes represent experiences of fear and insecurity whereby personal vulnerability was exacerbated by lack of cultural and gender awareness in higher education, including obvious examples of White ignorance. Institutional diversity was claimed, but this contrasted with authors’ experiences of exclusionary behaviour. Authors reported endemic racism and sexism, but that it was helpful when institutions provided support for these challenges. AE gives power, volume, and space to rarely heard minority voices. AE synthesis offers an overview of collective experience of similar phenomena or contexts. Such meta-studies are not common in the research literature, and this article provides both evidence of lived experiences of academic staff in 21st century higher education, and a purposeful guide to synthesizing AE research.
PREDMET STICANjA SVOJINE OKUPACIJOM U SRPSKOM I RIMSKOM PRAVU
Authors:   University of Kragujevac, Faculty of Law, Sovrlić Milica
Published: October 2022

By occupation, as the original mode of acquiring property, the individual acquires the ability to introduce things with attributes in legal transactions, we can say with the minimum conditions and without any formality. In certain historical periods, the occupation was much more economically significant than today, which is somewhat due to the existence of a much greater volume of natural resources and a lesser influence of the state through legal regulations regarding their exploitation. Among rules that regulate the ways of acquiring property, the occupation still exists, but may be seen greater strictness in defining and determining the conditions that must be met for one person one person to acquire property occupation. This strictness is present in determining things that can be acquired by occupation. Accordingly, the subject of the author's work are norms that regulate the acquisition of property by occupation in Serbian law and Roman law.
KOLIZIONOPRAVNO CEPANjE ZAOSTAVŠTINE USLED PRIMENE USTANOVE RENVOI I UKLANjANjE NASTALIH PROTIVREČNOSTI PRAVNIH NORMI
Authors:   University of Kragujevac, Faculty of Law, Đorđević Slavko
Published: October 2022

In Serbian private international law the so called scission of succession estate and application of several national laws to the different parts of deceased’s estate may be caused by renvoi (Art. 6 Serbian PIL Act). It may particularly happen when the conflict rule on succession of Art. 30 Serbian PIL Act refers to the foreign law whose conflict of law rules accept the concept of plurality of succession (scission of estate) which implies application of lex rei sitae to immovable property and application of personal law of deceased to movable property. In this paper author analyses the phenomena of scission of estate and institute of renovi by which scission could be caused, deals with the problem of contradictions of legal norms which arises as a consequence of application of two or more succession statutes and explains how these contradictions may be avoided by using the adaptation method of private international law.
PROMENE U PRAVNOM REGULISANjU DUŽNOSTI PRIJAVLjIVANjA POSLOVA I RADNjI U KOJIMA POSTOJI LIČNI INTERES
Authors:   University of Kragujevac, Faculty of Law, Mihajlović Borko
Published: October 2022

Amendments and supplements of the Serbian Company Law from June 2018 have significantly influenced the duty to report businesses and acts in which exists personal interest, which represents one of the five special duties towards company, according to the Serbian company law. The basic novelties in this area are inspired by the changes of the EU Directive on shareholders’ rights from May 2017. The subject of this paper is analysis of the mentioned changes and their relationship with the law which has not been changed, as well as its compliance with above mentioned Directive, through the overview of the procedure of application of the duty to report businesses and acts in which exists personal interest. The author in the paper analyses each phase of this procedure, while he particularly emphasizes the novelties which he considers as inadequate. Finally, the author gives concrete recommendations to the Serbian legislator, aimed at improvement of current legal regime of duty to report businesses and acts in which exists personal interest.
The Effectivity of Family Accompaniment For ROM Exercise Upon Elderly Post Stroke Patient With Hemiplegia
Authors: Mumpuni Mumpuni , Nuraeni Ani , Maidawilis Maidawilis , Nurulhuda Uun
Published: October 2022

The number of stroke patient with average above 60 years old are in second top rank  in Asia. Post stroke patient whose stay at home after hospitalization often had lack of treatment for ROM exercise by the believe of family that the exercise upon the elderly are not effective in ability of physical condition, uselless and wasting time. The purpose of this study is expected could give the description of the effect of accompaniment on family for ROM exercise upon post stroke elderly with hemiplegia whose been care in their own domestic in District of Pasar Minggu South Jakarta. The research are Quasi-experimental pre-post test with control group design. The sample of the study consist of  60 persons of family member which choose by purposive sampling as accordance as elderly with minimum of age 55 which got stroke with Hemiplegia at first time and been care in their own domestic. The result of the study shown that the mean difference are significant for motivation in control and intervention group 0,001 (p-value:0,005), significant in knowledge between control and intervention group 0,011 (p-value: 0,005), significant in ability for providing care for ROM exercise 0,006 (p-value: 0,05). Meanwhile the score of muscle strength had shown the difference between control and intervention group, although not significant statistically. As a result, family accompaniment could be able administered to the family with post stroke elderly.
Defect Reduction Analysis to Improve Glass Bottle Packaging Products Quality Using Statistical Process Control (SPC) at PT. Muliaglass Container (MGC)
Authors: Imaroh Tukhas Shilul , Mustofa Ali
Published: October 2022

Quality plays an important role, problems in the number of defects in production cause a decrease in quality. To prevent this increase in defective products, it is necessary to evaluate the most types of defects to determine the causes of defects so that corrective actions are obtained using statistical process control (SPC) methods and with 3 Pareto diagram controllers, control charts and fishbones. This research is intended to explore facts about Defect Reduction Through Statistical Process Control (SPC) for Product Quality Improvement and Supervision and to help determine the views on reducing the number of defects in products so as to increase the target of good product quality. The implementation of the results of this study shows a fairly good reduction in production defects based on the calculation results, namely before repairs from January to March 2021 total sales are 550,962 pc and after repairs in January to March 2022 a total of 496,260 pc so there is a decrease of 10% (54,702 pc). ) with a cost saving value of Rp. 59,318,001/mon.
Confiscation of Assets in The Corruption Crime
Authors: Hapsari Sulvia Triana , Madjid Abdul , Aprilianda Nurini
Published: October 2022

Corruption as an extraordinary crime so that the punishment is the Primum Remedium. Economic Analysis of Law can be used to increase the efficiency of handling corruption crimes (TPK) to provide a level of efficiency and a deterrent effect. The formulation of the problem in this research is how is the economic analysis of law in maximizing the looted assets from the crime of corruption? This research is based on judicial normative. The data were collected using the search method and literature review. Conclusion Based on the economic analysis of law, the shift in the orientation of punishment in criminal acts of corruption from corporal punishment to a combination of corporal punishment, large fines, confiscation of assets and impoverishment of perpetrators of criminal acts of corruption without diminishing the meaning of corporal punishment shows effectiveness and efficiency and will increase the deterrent effect for perpetrator.
Politeness Maxims as A Positive and Negative Speech Act by The Characters “Habibie & Ainun” (2012)
Authors: Salsabila Irma Nuraeni , Fransica Vika
Published: October 2022

A language is a tool for communicating in social life between individuals. Language makes people interact with each other. While the maxims is an important aspect of language so that the delivery and acceptance run well without causing problems in the future. This research uses a qualitative approach method with the analysis method, to conduct an in-depth analysis related to the findings of data from the film "Habibie & Ainun". Data retrieval is carried out by researchers with purposive sampling techniques where the selection of data and its use is only following the purpose of the study. The results showed that in the film "Habibie & Ainun" the characters more often use positive speech following existing norms and cultures.
Implementation of The Independent Learning Curriculum in Cirebon District
Authors: Hakim Arif Rohman , Nabila Maulina
Published: October 2022

Freedom to learn is an idea launched by the minister of education and culture, to produce superior human resources by prioritizing character education. This study aims to determine the implementation of independent learning policies in education in Indonesia. This study uses a literature review research method, while data collection techniques are carried out by exploring journals and other information relevant to the study. The results showed that the independent learning program launched by the Minister of Education and Culture Nadiem Makarim was to improve the education system in Indonesia. The independent learning program is relevant to the goal of national education, namely to form a young generation who is not only intellectually intelligent but also has good character traits such as responsibility, discipline, honesty, has the ability to think critically and analytically and become independent humans so that they are able to express their opinions without feeling scared and depressed. Based on the explanation that has been given to the implementation of the Free Learning Policy promoted by the Minister of Education of Indonesia Nadiem Makarim in Cirebon Regency, it is hoped that it can increase the education ranking of Cirebon which previously occupied the 25th position in West Java, to be able to rise to the top.
TEOLOGI TUBUH: MAKNA MATA SEBAGAI PELITA TUBUH MENURUT INJIL LUKAS 11:34 DAN BAPA GEREJA PHILOKALIA
Authors: Nesti Gulo
Published: October 2022

Dalam Lukas 11:34, Yesus menyebut “Mata adalah pelita tubuh.” Mata yang baik memberikan terang pada tubuh yang barasal dari mata hati sedangkan mata yang jahat menghasilkan kegelapan. Mata yang baik akan menghasilkan terang karena dari mata turun ke hati dan akan membuahi dosa. Pastikan yang kita kerjakan segala sesuatunya hanya yang kudus, berkenan di hadapan Tuhan, lakukan kebaikan terhadap semua orang dan tetap teguh pada iman yang memberikan keselamatan kepada kita. Pimpinlah mereka yang masih terhilang dengan kasih Tuhan dan jagalah hati dan diri kita sendiri agar kita tidak jatuh ke dalam dosa. Tunjukkan karakter yang baik supaya menjadi teladan bagi mereka dan kasihilah mereka seperti Tuhan Yesus Kristus mengasihi semua umatNya. Beritakanlah injil dan ajarlah mereka menyelaraskan hidup sesuai firman Tuhan, supaya mereka percaya dan diselamatkan. Setiap orang percaya harus memiliki sikap hati yang baik dan menjadi berkat bagi sesama.
ANALISA PERBANDINGAN EXPANTION JOINT JEMBATAN JENIS ASPHALTIC PLUG JOINT Dengan FINGER JOINT Pada JALAN TOL TANGERANG – MERAK
Authors: Artiwi Nila Prasetyo , Putra Among Wiria , Lestari Dinihari Mulya
Published: October 2022

Jembatan adalah suatu struktur kontruksi yang memungkinkan rute transportasi melalui sungai, danau, kali, jalan raya, jalan kereta api dan lain-lain. Oleh sebab itu, setiap komponen penyusun jembatan perlu mendapatkan perhatian khusus. Salah satu komponen penyusun jembatan adalah expansion joint atau siar muai. Sama halnya pada jalan tol Tangerang – Merak, jembatan tol yang terdapat disana menggunakan beberapa jenis expantion joint antara lain asphaltic plug, finger joint, dan strip seal joint. Tujuan analisa ini dilakukan untuk mengetauhi tahapan pekerjaan expantion joint asphaltic Plug dan finger joint, serta mengetahui perbandingan waktu, biaya pekerjaan,dan biaya pemeliharaan expantion joint selama 3 bulan. Metode pengumpulan data yang dikumpulkan berasal dari hasil observasi dan literatur, serta terbagi menjadi dua jenis yaitu data primer dan data sekunder. Dari hasil perhitungan celah sambungan siar muai didapat ∆L sambungan siar muai = 4,786 mm dan dari hasil analisa didapatkan untuk asphaltic plug ada 9 tahap pekerjaan dengan waktu 8 jam untuk pelaksanaan 3,60 m dengan biaya Rp. 1.067.996.074 dan biaya pemeliharaan Rp. 188.030.513. Sedangkan untuk Finger joint ada 9 tahap pekerjaan dengan waktu 18 jam untuk pelaksanaan 3,60 m dengan biaya Rp. 4.274.271.827 dan biaya pemeliharaan Rp. 4.849.109
PENGARUH KENDARAAN BERMOTOR TERHADAP PENCEMARAN UDARA DI KECAMATAN CIRUAS SERANG BANTEN
Authors: Fitriyah Fitriyah , Indriyani Yaneu Sri
Published: October 2022

Tujuan penelitian ini adalah untuk mengetahui tingkat pencemaran udara pada daerah wilayah kecamatan ciruas berdasarkan parameter TSP (Total Suspended Particulate) dan PM10 (Particulate Metter) berdasarkan kendaraan bermotor. Metode penelitian ini menggunakan metode eksperimentalmmenggunakan alat High Volume air Sampler (HVAS) dengan metode Gravimetri yang mengacu pada SNI 7119.3-2017 untuk pengukuran TSP dan SNI 7119.15-2016 untuk pengukuran PM10. Hasil pengukuran tingkat pencemaran udara pada wilayah Kecamatan Ciruas yang dilaksanakan selama lima hari dengan durasi 24 jam menghasilkan  konsentrasi TSP dengan nilai rata-rata sebesar 64,43 (µg/Nm3), sedangkan untuk konsentrasi PM10 dengan nilai rata-rata yang diperoleh sebesar 55,96 (µg/Nm3). Perbandingan konsentarsi TSP dan PM10 pada tahun 2015,2016,2017 dan 2020, Konsentrasi TSP dan PM10 tahun 2015 sebesar 138 (µg/Nm3) dan 67 (µg/Nm3),tahun 2016 sebesar 138 (µg/Nm3) dan 67 (µg/Nm3, tahun 2017 sebesar 203 (µg/Nm3) dan 90 (µg/Nm3), tahun 2020 sebesar 64,43 (µg/Nm3) dan 55,96 (µg/Nm3). Maka Berdasarkan PP No. 41 Tahun 1999 tentang Pengendalian Pencemaran Udara bahwa konsentrasi TSP dan PM10 pada daerah kecamatan ciruas kabupaten serang masih memenuhi standar baku mutu
PERENCANAAN STRUKTUR ATAP FROFIL BAJA WF
Authors: Darmiyanti Lydia , Rodji Ahmad Pahrul , Mumtaz Asaddulah
Published: October 2022

Rangka atap merupakan salah satu bagian dari struktur atap yang berfungsi untuk melindungi bangunan dari matahari maupun hujan. Material untuk rangka atap pada saat ini telah mengalami perubahan dari kayu ke material yang lebih mudah didapat, ekonomis, lebih ringan dan mudah dalam pemasangan. Baja profil WF (wide flange) salah satu alternatif rangka atap yang banyak digunakan. Berat profil WF yang relatif ringan dengan struktur yang padat menjadikan profil ini banyak digunakan untuk rangka kuda-kuda atap. Analisis ini dilakukan guna mengetahui kekuatan dari struktur kuda–kuda baja profil WF dan sambungannya. Metode analisa yang digunakan adalah metode LRFD yang dilakukan dengan bantuan program SAP 2000 v20 menganalisa konstruksi atap tersebut dan menggunakan bantuan program Idea StatiCa dalam menghitung sambungannya. Berdasarkan hasil yang diperoleh, kuda-kuda yang menggunakan profil WF 200.100.5,5.8 ini mampu menahan gaya-gaya yang bekerja pada struktur kuda -kuda tersebut, serta sambungan mencukupi untuk menahan gaya–gaya yang terjadi

 

Kata kunci: Metode LRFD, profil WF, kuda-kuda atap.
Comparative Analysis of First and Second Order Methods for Optimization in Neural Networks
Authors: KHANAL Auras , DİK Mehmet
Published: October 2022

Artificial Neural Networks are fine tuned to yield the best performance through an iterative process where the values of their parameters are altered. Optimization is the preferred method to determine the parameters that yield the minima of the loss function, an evaluation metric for ANN’s. However, the process of finding an optimal model which has minimum loss faces several obstacles, the most notable being the efficiency and rate of convergence to the minima of the loss function. Such optimization efficiency is imperative to reduce the use of computational resources and time when training Neural Network models. This paper reviews and compares the intuition and effectiveness of existing optimization algorithms such as Gradient Descent, Gradient Descent with Momentum, RMSProp and Adam that implement first order derivatives, and Newton’s Method that utilizes second order derivatives for convergence. It also explores the possibility to combine and leverage first and second order optimization techniques for improved performance when training Artificial Neural Networks.
Analysis of Seepage Through The Dam Considering Various Soil Characteristics Using an Experimental and The Finite Element Modeling Technique
Authors:   Department of Civil Engineering, University of Nigeria, Nsukka, Enugu State, 410101, Nigeria, Okeke, T. E.
Published: October 2022

In this study, the rate of seepage flow through the dam was investigated using both experimental and numerical modeling techniques. Two different types of soil samples were collected at a depth of 1m from the Auchi site in Edo State, Nigeria. The soil samples were subjected to preliminary tests such as the sieve analysis, the limit state (liquid limit, plastic limit and plasticity index), and the specific gravity test. Notable differences in the Geotechnical properties of two samples of soils were observed. The sieve analysis indicated that the particles passing through a 200-sieve number of size 0.075mm were 14.32% and 13.48% respectively. The liquid limit of sample 1 and sample 2 was determined to be 35% and 30%, the plastic limit 20.5% and 24.3%, the plasticity index 14.5% and 5.7% and the specific gravity of the two samples 2.63 and 2.65 respectively. Shear test was conducted to obtain the bearing capacity of soil using Terzaghi principle thereafter, the finite element analysis was used by applying SEEP/W of the Geo Studio program to determine the rate of flow of seepage through the dam. The result of the analysis showed that earthen dam without considering the core gave 12% difference in the seepage through the earthen material, the core of hydraulic conductivity 10 times less than that of the homogenous material gave 19.06% percentage difference seepage rate of flow with consideration of core with k 10 times less than homogenous material and the core of hydraulic conductivity 100 times less results gave 17.86% percentage difference for core of k 100 times less than homogenous material. Recommendations were made based on these results to reduce the rate of flow of seepage through the dam.
Vitex trifolia as Cyclooxygenase-2 Inhibitors in Anti-Inflammatory Drug Discovery
Authors:   Department of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, Ifora Ifora
Published: October 2022

Inflammation is involved in several stages of diseases such as cardiovascular diseases, asthma, diabetes, neurodegenerative diseases, or cancer. Cyclooxygenase-2 (COX-2) is an important enzyme that catalyzes the production of prostaglandins from arachidonic acid and has an important role in various inflammatory-related pathologies. The selective suppression of COX-2 over COX-1 is thought to be a useful approach for treating inflammation. Vitex trifolia is traditionally used for various inflammatory ailments, thus giving scope for anti-inflammatory studies. Since the action of Ethanol extract of Vitex trifolia (EEVT) on COX-2 has not been previously described. In this study, we further investigated the effect of Cyclooxygenase-2 inhibitory effects spectrophotometrically in ELISA readers and evaluated anti-inflammatory activity in the carrageenan-induced rat paw edema model. The edema volume was measured using a plethysmometer. The results showed that the EEVt (200, 400, and 800 mg/kg BW) had significant anti-inflammatory activity and the EEVt demonstrated a COX-2 Inhibitory effect. The percentage of COX-2 inhibition was 8,04%, 20,74%, 21,92%, and the percentage of inhibition of paw edema was 39,56%, 45,60%, and 40,56%, respectively. These findings suggest that Vitex trifolia leaves extracts to possess promising and remarkable anti-inflammatory activity, which is directed against the enzymatic activity of COX-2.
Implementación de modelos de cadena de suministro en circunstancias de COVID analizados vía equilibrio de Nash con Gambit
Authors:   Universidad Autónoma de Ciudad Juárez, Marín Díaz Adolfo , Ramírez Echevarría Ricardo ,   Universidad Autónoma de Ciudad Juárez, Pérez Domínguez Luis Asunción ,   Universidad Autónoma de Ciudad Juárez, Luviano Cruz David ,   Universidad Autónoma de Ciudad Juárez
Published: October 2022

El propósito de este documento es implementar un modelo de competencia centrado en las cadenas de suministro. De este modo, se plantea analizar los datos de dos compañías, el problema describe los mismos objetivos de mercado, una de estas compañías presenta problemáticas que dificultan su competencia respecto a la otra debido a diferentes escenarios causados por la COVID 19. En este sentido, el enfoque que se utilizo fue el cuantitativo, con un alcance descriptivo, para llevar a cabo la solución del problema planteado se aplicará un modelo ya existente de los escenarios mencionados anteriormente. De igual manera se utilizará el software “Gambit”, para determinar las soluciones con base de “Teoría de juegos”. Así mismo, debido a la naturaleza del programa “Gambit” se tendrán en cuenta ciertas modificaciones y adaptaciones que se requieran para resolver un problema en la cadena de suministro y analizar el caso numérico usando el método del “Equilibrio de NASH” y reflexionar la importancia de este tipo de análisis y estrategias en un entorno sumamente competitivo como es la industria manufacturera.