bluuebunny/crossref_metadata_2025 huggingface dataset:
Promosi Concept Store melalui Media Sosial
Authors: Rachmansyah Mochamad Raihan , Palapah Maya Amaliah Oesman
Published: July 2023

Abstract. Other. At the same time, they have to be able to overcome the competition in order to make their business runs well. One of the strategies to deal with this situation is doing promotional activities. These activities can be done offline or online. In addition, along with the development of the technology, the promotional activities continue to grow, especially the online one. Currently, online promotion is the choice of many business activists. Online promotion can be done through social media. One brand that uses it is HGL House, as a concept store that uses social media as a promotional medium. The social media used is Instagram, by utilizing the reels feature. The purpose of this study is to find out how the promotional activities carried out by HGL House through Instagram reels. The data to be obtained are the stages of planning, implementation, obstacles and evaluation of the promotional activities carried out. This research employs qualitative case study method. Data were collected through interviews, observations, and literature reviews. The results of this research are expected to result a better understanding in the implementation of promotional activities carried out from the planning, implementation, obstacles to evaluation stages carried out in these promotional activities associated with the three way strategy.

 

Abstrak. Banyaknya brand-brand bermunculan di kota Bandung menjadikan pesaing bermunculan. Para penggiat bisnis harus bisa mengatasinya agar bisnisnnya berjalan dengan baik. Salah satu caranya adalah dengan melakukan aktivitas promosi. Aktivitas promosi bisa dilakukan dengan cara offline maupun online. Seiring dengan perkembangan zaman dan teknologi, aktivitas promosi seakan terus berkembang. Saat ini promosi secara online menjadi pilihan yang banyak diilih oleh para penggiat bisnis. Promosi online dapat dilakukan dengan cara melalui media sosial. Salah satu brand yang memamnfaatakannya adalah HGL House sebagai salah satu concept store yang menggunakan media sosial yang dijadikan sebagai media promosi. Media sosial yang dipakai adalah instagram dengan memanfaatkan fitur reels. Tujuan penelitian ini adalah mengetahui bagaimana aktivitas promosi yang dilakukan oleh HGL House melalui instagram reels. Adapun hal yang ingin di peroleh adalah mengenai tahap perencanaan, pelaksanaan, hambatan dan evaluasi dari aktivitas promosi yang dilakukan. Metode yang digunakan dalam penelitian ini adalah kualtatif dengan pendekatan studi kasus. Pengumpulan data dilakukan dengan cara wawancara, observasi, dan studi pustaka. Hasil pada penelitian ini diharapkan dapat menghasilkan penerapan aktivitas promosi yang dilakukan dari mulai tahap perencanaan, pelaksanaan, hambatan hingga evaluasi yang dilakukan dalam aktivitas promosi tersebut dikaitkan dengan three ways strategy.
Implementasi CSR PT X dalam Membangun Ketahanan Pakan Ternak
Authors: Agung Setiawan  , Maman Suherman
Published: July 2023

Abstract.

PT X's social responsibility program itself refers to ISO 26000: 2010. Responsibility in the form of a form of concern and donation to national development. In this Corporate Social Responsibility program, issues and problems were found regarding the difficulty of obtaining good quality animal feed in Kertawangi Village, Cisarua District, West Bandung Regency. The research objective was to find out how the implementation process was, the obstacles that occurred, and the reasons for choosing Kertawangi Village, Cisarua District, West Bandung Regency. This study uses a qualitative method with a case study approach. Data collection methods were carried out using interview techniques, observation, literature studies, and documentation studies. The results of this study are: 1) PT X builds animal feed resilience, using four stages of CSR, namely the planning stage (social mapping), implementation (carrying out programs based on social mapping), evaluation (assessment of implemented programs), and reporting (form of responsibility to relevant stakeholders). 2) There were obstacles during the implementation of activities, namely there were technical, non-technical, and planting land obstacles for breeders. 3) PT X implemented the CSR program in Kertawangi Village where both of them experienced difficulties in obtaining good quality animal feed.

Abstrak. Program tanggung jawab sosial PT X sendiri mengacu pada ISO 26000:2010. Dalam program Corporate Social Responsibility ini ditemukan isu dan permasalahan mengenai sulitnya mendapatkan pakan ternak yang berkualitas baik di Desa Kertawangi, Kecamatan Cisarua, Kabupaten Bandung Barat. Tujuan penelitian adalah untuk mengetahui bagaimana proses pelaksanaannya, kendala yang terjadi, dan alasan memilih Desa Kertawangi Kecamatan Cisarua Kabupaten Bandung Barat. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus. Metode pengumpulan data dilakukan dengan menggunakan teknik wawancara, observasi, studi literatur, dan studi dokumentasi. Hasil dari penelitian ini adalah: 1) PT X membangun ketahanan pakan ternak menggunakan empat tahapan CSR yaitu tahap perencanaan (social mapping), implementasi (program berbasis tentang pemetaan sosial), evaluasi (penilaian terhadap program yang dilaksanakan), dan pelaporan (tanggung jawab kepada pemangku kepentingan terkait). 2) Terdapat kendala selama pelaksanaan kegiatan yaitu adanya kendala teknis, non teknis, dan lahan tanam bagi para penangkar. 3) PT X melaksanakan program CSR di Desa Kertawangi di mana keduanya mengalami kesulitan dalam mendapatkan pakan ternak yang berkualitas baik.
PERFIL EPIDEMIOLÓGICO DAS INTERNAÇÕES PELO SUS NOS HOSPITAIS DE UMA CIDADE DO INTERIOR DO ESTADO DO PARANÁ NO PERÍODO DE JANEIRO DE 2020 A DEZEMBRO DE 2020
Authors:   , Sfredo Isabelle
Published: July 2023

Introdução: Estudos epidemiológicos sobre perfil de internações hospitalares são
fundamentais para apoiar as políticas de saúde voltadas à determinadas populações. Este
estudo teve como objetivo, traçar o perfil das internações hospitalares na cidade de Pato
Branco-PR, no período de janeiro a dezembro de 2020. Metodologia: A população analisada
foi de pacientes que deram entrada nos Hospitais de Pato Branco na modalidade de internação
pelo Sistema Único de Saúde, no período de janeiro de 2020 a dezembro de 2020, que tinham
18 anos ou mais. As informações foram coletadas através de dados codificados cedidos pelos
hospitais do município devidamente cadastrados no SUS. Essa pesquisa foi aprovada pelo
Comitê de Ética em Pesquisa (CEP), parecer nº 4.410.168, na data de 19 de novembro de
2020. A análise de dados foi feita de modo descritivo e quantitativo, de modo a não distinguir
os hospitais e evitar ao máximo a quebra de sigilo profissional. Resultados: No período de
janeiro de 2020 a dezembro de 2020, verificou-se um montante de 10.346 internações. A
faixa etária mais prevalente foi a de 18 a 29 anos no sexo feminino, e 60 a 69 anos no sexo
masculino. A causa ginecológica e obstétrica foi a que obteve maior quantidade de
hospitalização, seguido de causas em clínica médica e ortopédicas/traumatológicas,
respectivamente. Conclusão: O conhecimento desses dados é fundamental para criação e/ou
aprimoramento de assistências em saúde que visam atingir vantagens na saúde populacional
das mais diversas camadas etárias e gêneros.
CUIDADOS DE ENFERMAGEM AO IDOSO HIPERTENSO NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Carvalho Natacha Caroline Fernandes de Araújo , Silva Daiane de Matos , Santos Mayconn Douglas Alves dos , Abreu Irla Alves de , Amorim Thércia Máyra dos Santos , Santos Isabella Pinto dos , Santos Karen Stefane Feitosa dos , Pereira Thalia Jeovana da Silva
Published: July 2023

Objetivo: Analisar na literatura científica os cuidados de enfermagem ao idoso hipertenso na
atenção primária à saúde. Metodologia: Trata-se de uma revisão integrativa da literatura, na
qual a coleta e análise de dados foi proveniente da BVS através das bases de dados da
LILACS e SCIELO. A busca ocorreu no mês de fevereiro a março de 2023. Foram
encontrados 104 estudos nas bases selecionadas e selecionados 07 estudos para compor a
revisão. Resultados: Conforme os estudos analisados, constata-se que a hipertensão arterial é
um problema de saúde pública com alta prevalência na população idosa, tal realidade
acontece devido os hábitos de vida irregulares desse grupo, desse modo a equipe de
enfermagem é essencial no cuidado do idoso, por meio de ações educativas com o intuito de
incentivar o idoso ao tratamento da patologia o que consequentemente influencia na melhor
qualidade de vida e promoção da saúde. Conclusão: Nesse sentido, os cuidados de
enfermagem na atenção primária de caráter clínico e educativo se mostram como
imprescindíveis para que haja uma melhor compreensão da doença, bem como uma maior
eficácia no tratamento, o que de certa forma vem a repercutir na melhor qualidade de vida do
idoso hipertenso.
A Psicogênese da Língua Escrita: Desenvolvimento e Aquisição da Escrita na Infância
Authors: Giordani Kassiani
Published: July 2023

A língua escrita é uma forma de comunicação e expressão essencial para a sociedade atual. O processo de aquisição e desenvolvimento da escrita é uma habilidade complexa que envolve a interação de diversos fatores cognitivos, sociais e linguísticos. A psicogênese da língua escrita é o campo de estudo que se dedica a investigar como as crianças adquirem e desenvolvem a capacidade de ler e escrever.
Biochemical effect of monkey tail on albino rabbits
Authors: Tata FC  , Igwe CU  , Chinyere IO  , Olua Victor
Published: July 2023

Monkey tail is an addictive alcoholic drink made from fermented combo of marijuana leaves or seeds and dry/local gin. This study examined the effect of alcoholic concoction of marijuana leaves on blood chemistries of albino rabbits. Sixteen rabbits weighing 1.5 – 2.0 kg were randomly allocated into four groups and orally administered 2.5 ml/kg body weight daily of the marijuana concoction for 0, 10, 20 and 30 days respectively. There was no significant (p>0.05) difference in the serum total protein, albumin and globulin concentrations of the treated animals. The serum AST and ALT activities increased significantly (p<0.05) with increase in the duration of treatment. There were generally no significant (p>0.05) differences in the kidney function parameters of the animals over the treatment duration. Histological analysis of the liver and kidney tissues of the animal administered monkey tail for 30 days showed evidence of fatty liver and acute interstitial nephritis respectively. The results showed that monkey tail on prolonged consumption could have negative hepatic and renal effects in animals with mild alterations in the lipid profile.
Medical cannabis: Exploring therapeutic perspectives and regulatory context
Authors: Bachir NABTI
Published: July 2023

The utilization of medical cannabis, specifically the therapeutic potential of cannabinoids, has garnered significant attention in recent years. This literature review aims to delve into the intersection between therapeutic perspectives and the regulatory context surrounding medical cannabis. Key terms such as medical cannabis, cannabinoids, regulation, chronic pain, and multiple sclerosis (MS) will be explored to provide a comprehensive understanding of the subject. Therapeutic applications of medical cannabis will be examined, with particular focus on its potential in managing chronic pain and alleviating symptoms associated with multiple sclerosis. Furthermore, the complex regulatory landscape surrounding medical cannabis will be analyzed, taking into account various legal frameworks, guidelines, and constraints imposed by governing bodies.This article highlights emerging scientific evidence supporting the use of medical cannabis, including the efficacy of cannabinoids in pain management and their impact on multiple sclerosis symptoms. Additionally, it will address the challenges faced by healthcare professionals, patients, and policymakers due to varying regulations across jurisdictions.
Comorbidities of geriatric psoriasis: A cross-sectional study with 75 patients
Authors: Alper Alyanak  , Kıymet Handan Kelekci  , Nurhan Döner Aktaş  , Işıl Ezgi Urgancı Tatlı  , Büşra Emir
Published: July 2023

Objective: Our aim in this study was to determine comorbid diseases in the elderly with psoriasis. Methods: This cross-sectional study was conducted on 75 psoriasis patients, aged 65-85 years, and 75 control patients without psoriasis. Psoriasis clinical features and comorbidities were recorded during the physical examination and taking anamnesis. Comorbidities were also searched from the hospital registration system. Comorbidities were compared between the groups. Results: It was determined that metabolic syndrome-associated diseases and other diseases which were chronic bronchitis, pneumonia, hypothyroidism, and depression were statistically increased from the control group (p<0.05). Obesity was found to be high in both groups but was not statistically different between the groups (p>0.05). Conclusion: Our findings show that metabolic syndrome-associated diseases were all increased and should be investigated in geriatric psoriasis patients. Larger sample size studies would better delineate the other comorbidities. Systemic therapy should be carefully evaluated because of systemic involvement in psoriasis and also side effects on major organ systems.
Antioxidant and immunological evaluation of Ceratonia siliqua on Methotrexate induced Albino mice male
Authors: Noor Khairullah Ibrahim  , Farah T. O. Al-Jumaili  , Widad j. Atia
Published: July 2023

Carob (Ceratonia siliqua) plant was frequently used to cure a variety of health issues. This study aimed to evaluate the total flavonoid, phytochemical compounds, antioxidant activity In vitro, as well as immunological potential of Ceratonia siliqua methanolic extract in vivo through determination of total and absolute count of white blood cell on albino male mice. The result showed that Ceratonia siliqua contain (224.5±37.86) of flavonoid compound, in addition of many bioactive phytochemical compounds like (tannin, glycoside, alkaloid, polyphenol, and glycoside). Antioxidant activity indicated that the ability of methanolic extract of Ceratonia siliqua plant to scavenging free radical In vitro in all concentration uses (0.04, 0.08, 0.16, 0.32 and 0.64 mg/ml) when compared with trolox (vit E). Immunological parameters indicated the ability of plant to enhance the immunity by increase WBCs count (7166 cell/cu.mm.blood) in comparison with positive (methotrexate) and negative control, as well as increase in lymphocytes (3700 cell/cu.mm.blood) , neutrophil (2985 cell/cu.mm.blood) and monocyte (481 cell/cu.mm.blood) All of these effect attributed to active phytochemical constituents in plant extract.
Lassa fever: knowledge deficits among nurses and non-nurses at a tertiary hospital in Ondo, southwest Nigeria
Authors: Akinwumi Ayodeji Akinbodewa  , Michael Olumide Gbala  , Oluwole Olugbenga Ige  , Olaseinde Bello  , Bola Francis Akinkunmi  , Gabriel Fabusuyi
Published: July 2023

Introduction: Lassa fever is endemic to many African countries with knowledge deficit linked to increased exposure, morbidity and mortality among healthcare workers. Objectives: To assess knowledge deficit among nurses and non-nurses. Materials and methods: This was a descriptive, cross-sectional study conducted at the University of Medical Sciences Teaching Hospital, Ondo State, Nigeria. Results: There were 59 (48.8%) nurses and 62 (51.2%) non-nurses with a male to female ratio of 1:2.9. Their mean age was 34.2±8.0 years. Nurses and non-nurses performed well in 30 (62.5%) and 26 (54.2%) out of 48 knowledge domains respectively. Participants performed poorly in (i) early identification of disease such as negative malaria test in a feverish patient (32.2%) and role of high index of suspicion (34.7%); (ii) knowledge of transmission via body fluid {sweat (43%), saliva (28.9%), semen (21.5%)}, and (iii) decontamination with methylated spirit (22.3%), chlorine (32.2%) and formalin (20.7%)}. Nurses performed better than non-nurses in identifying (i) Mastomys natalensis as carrier for Lassa fever virus (p=0.049) (ii) deafness as a Lassa fever sequelae (p=0.041) (iii) semen (p=0.008) and vagina secretion (p=0.035) as routes of transmission (iv) nurses being directly at risk of Lassa fever (p = <0.01) (v) patient avoidance (p=0.004), hand washing (p=0.004), use of hand sanitizer (p=0.046) and safe waste disposal (p=0.047) as helpful in reducing Lassa fever infection. Conclusion: Knowledge of Lassa fever among healthcare workers in the tertiary hospital was generally unsatisfactory with serious knowledge deficits in many domains.
Prostate Cancer Volumetric Arc Therapy (VMAT) Analysis
Authors: Aime M Gloi
Published: July 2023

Aim: The purpose of this study was to derive radiobiological parameters from the dose volume histogram of patients that undergone prostate cancer radiotherapy via the VMAT technique. Material and Methods: A total of twenty-two cases of prostate cancer of 70.2 and 81 Gy were selected for this study. Radiobiological parameters were evaluated by the Poisson equation for the tumor and LKB model for organs at risk. Results: For prostate tumor, the average TCP was 96.28, 86.45, 68.57 for α/β of 1.2, 3.0, and 10, respectively. The average EUD was 37.98 Gy, 59.23 Gy, 21.19 Gy, 20.65 Gy, 16.32 Gy, and 21.87 Gy for bladder, rectum, right femoral head, left femoral head, small bowel, and large bowel respectively. The average NTCP was 7.6 % for the rectum and negligible for other organs at risk. Conclusion: NTCP for critical organs and TCP for prostate cancer can be determined via dose volume histogram.
Bayesian three-stage a-optimal design for generalized linear models
Authors: Ali H  , Nwaosu S. C  , Lasisi K. E  , Abdulkadir A
Published: July 2023

Bayesian sequential designs are increasingly receiving attention in recent years, especially in clinical trials and biomedical research. Bayesian sequential design process can utilize the available prior information of the unknown parameters so that a better design can be achieved. In this paper, a hybrid computational method, which consists of the combination of a rough global optima search and a more precise local optima search, is proposed to efficiently search for the Bayesian A-optimal designs for multi-variable generalized linear models. Specifically, Poisson regression models and logistic regression models are investigated. Designs are examined for a range of prior distributions and the equivalence theorem is used to verify the design optimality. Design efficiency for various models were examined. Furthermore, the idea of the Bayesian sequential design is introduced and the Bayesian three-stage A-optimal design approach is introduced for generalized linear models. With the incorporation of the first stage data information into the second stage, the second stage data information into the third stage, the three-stage design procedure improved the design efficiency and produce more accurate and robust designs. The Bayesian three-stage A-optimal designs for Poisson and logistic regression models are evaluated based on simulation studies. The Bayesian three-stage A-optimal design is superior to the two-stage A-optimal design approach in terms of design optimality and efficiency criteria.
Ethical issues in internet-based journalism practice in Nigeria
Authors: Ugo Solomon Ugo  , Anruchi Peter-Wagbara  , Okoro Jude Omaka
Published: July 2023

The guiding and central narrative of ethical issues in Nigeria is the alarming spread of fake news, hate speech, source credibility, quackery, poor internal censorship and other unwholesome practices resulting to serious ethical issues among internet based journalism platforms in Nigeria. The world has been engulfed in a spectre of fake news and disinformation with less attention to ethically sound reporting that has been the most potent tool for objective journalism across the world. People are more concerned with hot news reporting against balanced reporting where all sides are displayed and this has shown less integrity on media practice.Therefore, this study examines ethical issues in internet based journalism practice in Nigeriaagainst a sprawling fake news syndrome among internet based platforms with a view to examining factors that trigger ethical concerns among internet based journalism practitioners.The study was anchored on the Social Responsibility Theory with focused group discussion guide and key informant interview as instruments for data collection. systematic sampling technique was used in selecting 5,944 registered journalists in Nigeria, media scholars and Nigerian Union of Journalists’ ethics committee drawn from the six geo-political zones, data from discussants were analysed using detailed, orient probes and discussions.Among other findings, the study revealedthat there is a dearth in comprehensive knowledge of media laws because most practitioners are not aware of the legal ramification of certain media practice which must be adhered to in performing key role conceptions of the media, source credibility occasioned by a clearly defined editorial policy would be very useful in addressing ethical issues of fake news and hate speech prevalent among practitioners of internet based journalism platforms in Nigeria and adherence to ethical concerns is being hampered by untrained practitioners parading themselves as media influencers on different internet based journalism platforms.The study recommended that to curb the rising trend of ethical issues among internet based journalism practitioners in Nigeria, there should be a deliberate effort to increase the level of awareness and adherence to media laws in order to create online news platforms devoid of legal issues, strong regulatory framework by government and the Nigerian Union of Journalists to ensure that internet based journalism platforms instill editorial philosophy and constant training and retraining of practitioners of internet based journalism platforms in order to raise the bar against flagrant disregard for ethical principles of journalism.
Synthesis and in vitro anticancer activity of novel 1,4-dimethyl-9-H-carbazol-3-yl) methanamine derivatives against human glioma U87 MG cell line
Authors: Nitin Kumar  , Neetika lal  , Vishal Nemaysh  , Pratibha Mehta Luthra
Published: July 2023

Glioblastoma Multiforme (GBM) is most aggressive type of brain tumor in adults. 1,4-dimethyl carbazoles exhibits significant anticancer activities in literature. In this research article, we synthesized a series of novel 1,4-dimethyl-9-H-carbazol-3-yl)methanamine and its derivatives (13-24) and evaluated their in vitro cytotoxicity activities against human glioma U87 MG cell line using MTT assay for 24 h phase time period. All final carbazole derivatives were well confirmed by NMR and HRMS spectroscopy techniques. In series, few compound (15-17) found excellent in vitro anticancer activity (IC50) values 18.50 µM, 47 µM and 75 µM respectively against human glioma U87MG cell line compare to standard drugs used in brain cancer such as Carmustine (IC50 = 18.24 µM) and Temozolomide (IC50 = 100 µM) respectively. Among these derivatives, compound 15 was found to have the most potent cytotoxic effect on tested glioma cell line. This study supported that 1,4-dimethyl-9-H-carbazol-3-yl)methanamine derivatives found significant anticancer potential against human glioma U87MG cell line.
UPAYA MENINGKATKAN PENGETAHUAN KESEHATAN GIGI DAN MULUT MELALUI EDUKASI BAHAYA PENGGUNAAN �BEHEL FASHION� PADA MASYARAKAT MARGASARI
Authors: Suhartono Budi , Hutami Islamy Rahma , Mayangsari Regilia Shinta , Yuniar Savira Nurazky , Indrawati Silvia Vera , Dimas P.P Muhammad
Published: July 2023

Background: Today, many teenagers in Indonesia are using braces not as orthodontic appliances for the treatment of malocclusion but only as a �fashion� . Dental treatment that carried out by incompetent operators can actually cause far greater dangers and losses. The impact that can occur due to the use of

braces by dental technicians can arise from tooth decay, plaque accumulation, root resorption, bone resorption, inflammation of the supporting tissues of the teeth, to disorders of the temporomandibular joint. Method: The solution to the problem is carried out by educating the community, one of them are in Margasari, Tegal. Dental Health Education is carried out using poster media to make it more interactive, effective and efficient. Evaluation of the implementation is done by using a questionnaire. The results of the questionnaire were tabulated using SPSS with the Wilcoxon non-parametric test method. Result: wilcoxon signed rank shows that there are 0 negative ranks, 24 positive ranks, and 1 ties. Z value based on negative ranks are -4.322 Conclusion: There is an increase in knowledge of respondents after being

given education.
PENGABDIAN MASYARAKAT DAN SURVEY INDEKS DMF-T DAN def-t PADA ANAK SEKOLAH DASAR NEGERI 07 MARGASARI, KECAMATAN MARGASARI, KABUPATEN TEGAL, JAWA TENGAH
Authors: Hadianto Eko , Fathurrahman Helmi , Mayangsari Regilia Shinta , Yuniar Savira Nurazky , Indrawati Silvia Vera , Dimas PP Muhammad
Published: July 2023

Background: Caries is a chronic disease of the dental hard tissue. The main cause of this disease is plaque bacteria, starting with the formation of white spot lesions due to the dissolving of minerals in tooth enamel caused by acids from the metabolism of bacterial carbohydrates. Caries often occurs in elementary school children because they tend to consume a lot of cariogenic food. The prevalence of caries can be reduced by preventive efforts. Several preventive efforts can be made by providing sufficient information, reducing cariogenic food consumption, always maintaining oral and dental hygiene and preventive dentistry actions. Method: This community service located at SD N Margasari 07. The counseling activity uses phantom and video animation followed by DMF-T/def-t data collection. Result: It was found that 41.8% of students had high category DMF-T/def-t index Conclusion: It is necessary to have a sustainable program to increase children's knowledge and awareness in maintaining dental and oral hygiene including promotive, preventive and curative efforts.
PEMBERDAYAAN MASYARAKAT DESA MARGASARI MENUJU DESA BEBAS KARIES MELALUI PRODUK BERES (BEBAS KARIES)
Authors: Setyaningrum Yunita , Nurhapsari Arlina , Mayangsari Regilia Shinta , Yuniar Savira Nurazky , Indrawati Silvia Vera , Dimas P. Muhammad
Published: July 2023

Background: The Global Burden of Disease Study 2019 estimates that 3.5 billion people worldwide experience dental and oral health problems, with dental caries being the most common disease. The 2018 RISKESDAS data shows that the greatest caries prevalence is in the 5-year-old (93.4%), 12-year-

old (68.8%), 15-year-old (68.1%), 35-44 years (92.1%) and 65 years old. -74 years (95.2%). Dental caries has an impact on the quality of life of the sufferer which can interfere with daily activities so that efforts are needed and people become more aware and care about their oral health. Method: The solution to the problem is carried out by educating the community, one of them are in Margasari, Tegal. Dental Health Education is carried out using poster media to make it more interactive, effective and efficient. Evaluation of the implementation is done by using a questionnaire. The results of the questionnaire were tabulated using SPSS with the Wilcoxon non-parametric test method. Result: wilcoxon signed rank shows that there are 0 negative ranks, 24 positive ranks, and 1 ties. Z value based on negative ranks are -4.322 Conclusion: There is an increase in knowledge of respondents after being

given education.
Reflective Journals
Authors: Shannon Tony
Published: July 2023

A reflective journal helps to think honestly about one’s actual thinking. This can be uncomfortable at first!
Summary of and Comments on Strengthening Skills: Expert Review of Australia's Vocational Education and Training System
Authors: Joyce Steven
Published: July 2023

The following extracts have been compiled in this order to give a feeling for the total report (168 pages). The order of what follows is quite different from Joyce. It has been summarised this way for the benefit of readers who are not involved in the VET sector on a day-to-day basis. Most of the data are from 2017-2018. The summary is by Tony Shannon; it has no official status. To give perspective to this important report, the summary and comments are in three parts, namely, A general view of Australian Vocational Education & Training Recommendations – road map Some concluding comments
Modeling the Population Demographics & Viability of Imperiled Guzmania monostachia Populations
Authors: Pennington Helen , Lingareddy Pranay , Bodine Erin
Published: July 2023

Guzmania monostachia is a large, long-lived bromeliad whose leaves grow in a rosette pattern and is native to the Americas, but endangered in Florida due to damage caused by the invasive weevil Metamasius callizona. Each G. monostachia rosette can reproduce sexually via flowers or asexually by producing clonal offshoot rosettes. We model the population dynamics and demographic structure of a G. monostachia population using a Lefkovitch matrix model where each state represents a demographic class of rosettes. Model analysis over a range of uncertain parameters show the conditions under which a G. monostachia population is viable in the absence and presence of M. callizona, and the expected demographic structure under those conditions. In particular, our analysis illustrates that proportional reductions in survival have a qualitatively stronger impact on population viability than proportion reductions in clonal fecundity.
TABOT TRADITION AND ACCULTURATIVE RELIGIOUS TRADITION OF THE BENGKULU COMMUNITY
Authors: Khairuddin Khairuddin , Man Yovenska L.
Published: July 2023

Abstract: This article aims to explain the Tabot tradition and its cultural construction with the Bengkulu people as a minority group. The Tabot tradition experienced a kind of acculturation process in which two or more cultures met and made contact. Using Berry’s acculturation theory with a qualitative approach and ethnographic methods, this study resulted in a finding that the Tabut tradition resulted from a process of cultural acculturation between different religious and cultural contacts. In its journey, the Tabot is no longer a non-formal tradition but has become a local Bengkulu community organisation with the formation of the Tabot Harmony Family (KKT). The strategy chosen by KKT is to maintain its cultural and community heritage is integration. In this context, integration means maintaining the original culture and cultural contact.

Keywords: Tabot, religious-cultural traditions, local Islam, acculturation

 

Abstrak: Artikel ini bertujuan untuk menjelaskan adat Tabut dan konstruksi budayanya dengan masyarakat Bengkulu sebagai sebuah kelompok minoritas. Adat Tabut mengalami semacam proses akulturasi di mana dua atau lebih budaya bertemu dan melakukan kontak. Menggunakan teori akulturasi Berry dengan pendekatan kualitatif dan metode etnografi, penelitian ini menghasilkan sebuah temuan bahwa Tabut adalah hasil dari proses akulturasi budaya antara kontak agama dan budaya yang berbeda. Dalam perjalanannya, Tabut bukan lagi sebuah adat tradisi non-formal, melainkan telah menjadi sebuah organisasi masyarakat lokal Bengkulu dengan terbentuknya Keluarga Kerukunan Tabut (KKT). Strategi yang dipilih KKT ialah untuk mempertahankan warisan budaya dan komunitasnya adalah integrasi. Dalam konteks ini, integrasi berarti mempertahankan budaya asli dan tetap melakukan kontak budaya.
Kata Kunci: Tabot, Tradisi agama-budaya, Islam lokal, Akulturasi
IDEOLOGICAL CONTESTATION ON YOUTUBE BETWEEN SALAFI AND NAHDHATUL ‘ULAMA IN INDONESIA
Authors: Nur'aeni Ulvah , Ramdan Arfian Hikmat
Published: July 2023

Abstract: This research spotlights YouTube’s utilization as a platform for intriguing Muslims and proselytizing Salafi and Nahdhatul 'Ulama's (NU) doctrines in the context of ideological contestation in Indonesia. This aim was motivated by the struggle for religious authority between NU and Salafis that has occurred in Indonesia since the beginning of the emergence of Salafis in the 1970s. The doctrine of Puritanism brought by Salafis is the key to the ideological battle with NU, which has the opposite doctrine. Thus, the contestation spread to the fight for the masses. One medium used as an object for spreading doctrine is YouTube. This use of YouTube is encouraged by their awareness that YouTube is an effective platform for proselytizing and arguing with each other. Therefore, this research explores the ideological contestation of the two groups from the aspect of the doctrine they spread and the ways they attract the masses by analyzing lecture videos from YouTube channels affiliated with each group. Based on the content and video quantity, this research argues that the massive method of being charged with Salafis is slowly becoming a strong challenge for the existence of NU. The method used is a theory by Heidi A. Campbell regarding online authority.

Keywords: Ideological Contestation, Nahdhatul ‘Ulama, Religious Authority, Salafi, YouTube.

Abstrak: Penelitian ini menyoroti penggunaan YouTube sebagai platform untuk membangkitkan minat umat Islam dan menyebarkan doktrin Salafi dan Nahdhatul 'Ulama (NU) dalam konteks kontestasi ideologi di Indonesia. Tujuan ini dilatarbelakangi oleh perebutan otoritas keagamaan antara NU dan Salafi yang terjadi di Indonesia sejak awal kemunculan Salafi pada tahun 1970-an. Doktrin puritanisme yang dibawa oleh Salafi menjadi kunci pertarungan ideologis dengan NU yang memiliki doktrin sebaliknya. Dengan demikian, kontestasi menyebar dalam konteks perebutan massa. Salah satu media yang digunakan sebagai sarana penyebaran doktrin adalah YouTube. Penggunaan YouTube ini didorong oleh kesadaran mereka bahwa YouTube adalah platform yang efektif untuk berdakwah dan saling berdebat. Oleh karena itu, penelitian ini mengeksplorasi kontestasi ideologi kedua kelompok tersebut dari aspek doktrin yang mereka sebarkan dan bagaimana menarik massa dengan menganalisis video ceramah dari video YouTube yang berafiliasi dengan masing-masing kelompok. Berdasarkan kuantitas konten dan video, penelitian ini berargumen bahwa metode masif yang digunakan oleh Salafi perlahan menjadi tantangan kuat bagi eksistensi NU. Metode yang digunakan adalah teori Heidi A. Campbell mengenai otoritas online.
Kata Kunci: Kontestasi Ideologi, Nahdhatul ‘Ulama, Otoritas Keagamaan, Salafi, YouTube
Моделирование процесса высвобождения винпоцетина из сплава с b-циклодекстрином
Authors: Полковникова Ю.
Published: July 2023

Определено оптимальное соотношение винпоцетина и b-циклодекстрина в лекарственной форме (1:2 или 1:5) по результатам моделирования молекулярной динамики высвобождения действующего вещества в водную среду. Молекулярную динамику высвобождения винпоцетина из поливинилпирролидона моделировали в течение 100 нс с использованием программы Gromacs 2019 в силовом поле Gromos 54a7. Равновесие при высвобождении винпоцетина из исследуемого носителя наступает быстрее при соотношении винпоцетина с носителем 1:5 по сравнению с соотношением 1:2. Эффективность высвобождения винпоцетина при pH 2,0 выше по сравнению с высвобождением в нейтральной среде.
Накопление в лекарственном растительном сырье и извлечение в настои и отвары токсичных микроэлементов
Authors: Дьякова Н.
Published: July 2023

Представлены результаты экспериментального изучения особенностей накопления в лекарственном растительном сырье (ЛРС) и извлечения в настои и отвары токсичных микроэлементов. В качестве объектов исследования использовали фармакопейные виды ЛРС: листья — крапивы двудомной и подорожника большого; цветки — пижмы обыкновенной и липы сердцевидной; траву — пустырника пятилопастного, полыни горькой, тысячелистника обыкновенного, горца птичьего; корни — лопуха обыкновенного и одуванчика лекарственного. Микроэлементный состав образцов изучали масс-спектроскопическим методом после кислотно-микроволнового разложения. Изучаемые виды сырья содержат токсичные микроэлементы в количестве от 19 до 1403 мкг/г, что составляет 0,05 – 2,41 % общего элементного комплекса. Содержание токсичных микроэлементов в водных извлечениях в общей сложности варьировало от 0,19 до 5,35 мкг/г (0,01 – 0,25 % общего минерального комплекса препаратов). Резко выделяющимся содержанием токсичных микроэлементов выделяются водные извлечения листьев подорожника большого, травы горца птичьего, корней лопуха обыкновенного, что преимущественно объясняется относительно высоким содержанием алюминия (более 2 мкг/мл). Степень перехода различных элементов по цепочке «почва – ЛРС – водные извлечения» сильно варьирует. Зависимости содержания токсичных микроэлементов в настоях и отварах от содержания их в лекарственных растениях показывают, что при возрастании концентрации всех определяемых элементов в сырье увеличивается их концентрация в водных извлечениях. При возрастании содержания токсичных микроэлементов в растении степень их перехода в водные извлечения снижается.
Практические подходы к биосинтезу рекомбинантных белков
Authors: Бытяк Д. , Хорошилова Г. , Гнеушев А. , Сидоров П. , Гусаров Д.
Published: July 2023

На сегодняшний день наблюдается активный рост интереса к получению биологически активных молекул, путем культивирования генно-инженерно-модифицированных штаммов. При этом наиболее изученной и часто применяемой является экспрессия в бактериальных системах. В данной работе были определены оптимальные параметры ведения процесса культивирования генно-инженерного модифицированного штамма-продуцента E. coli агониста рецептора GLP-1. Определено влияние времени индукции, стартовой оптической плотности на момент индукции, концентрации индуктора, температуры и значений pH на накопление клеточной массы и синтез целевого белка. На основании данных, полученных в ходе исследований, определены оптимальные значения каждого исследуемого параметра, обеспечивающие эффективный биосинтез агониста рецептора GLP-1 при культивировании E. coli.
Разработка и валидация методики количественного определения гиалуроната натрия в жидкой лекарственной форме
Authors: Amandusova A. , Kovalenko A. , Morozov A. , Savelyeva R/ , Ostapyuk O. , Persanova L. , Andreevicheva T. , Beniashvili A. , Shestakov V. , Polyakov S. , Mekhonoshina E.
Published: July 2023

Предложена методика количественного определения гиалуроната натрия в жидкой лекарственной форме методом турбидиметрического титрования. Данный метод основан на определении концентрации вещества в растворе по возрастанию мутности (уменьшение пропускания) при добавлении титранта. В качестве осаждающего компонента использовали цетилпиридиния хлорид. Методика валидирована по показателям: специфичность, линейность, правильность, промежуточная (внутрилабораторная) прецизионность, повторяемость (сходимость). По результатам валидационных испытаний все перечисленные параметры соответствуют критериям приемлемости. Методика показала линейный характер зависимости в диапазоне концентраций 3,2 – 4,9 мг/мл.
Транссредовой переход лантаноидов по цепочке «почва – лекарственное растительное сырье – водные извлечения»
Authors: Дьякова Н.
Published: July 2023

Представлены результаты экспериментального изучения транссредового перехода элементов группы лантаноидов по цепочке «почва – лекарственное растительное сырье (ЛРС) – водные извлечения». В качестве объектов исследования использовали фармакопейные виды ЛРС: листья крапивы двудомной и подорожника большого; цветки пижмы обыкновенной и липы сердцевидной; траву пустырника пятилопастного, полыни горькой, тысячелистника обыкновенного и горца птичьего; корни лопуха обыкновенного и одуванчика лекарственного. Микроэлементный состав образцов изучали масс-спектроскопическим методом после кислотно-микроволнового разложения. Общее содержание лантаноидов в изучаемых видах ЛРС варьировало от 0,08 до 2,41 мкг/г. Наиболее высокий уровень концентрации лантаноидов отмечен в исследуемых корнях растений, а также в траве горца птичьего и листьях подорожника большого — 1,20 – 2,41 мкг/г. Расчет коэффициентов биологического поглощения показал, что все элементы группы лантаноидов относятся к элементам слабого накопления и очень слабого захвата. Степень транссредового перехода лантаноидов по цепочке отличалась невысокими числовыми значениями и не превышала 0,27%. Наиболее высокие значения данного показателя отмечены для листьев подорожника большого, а также для корней лопуха обыкновенного и травы горца птичьего.
Фитохимическое изучение травы Orthilia secunda (L.) house
Authors: Турусова Е. , Насакин О.
Published: July 2023

Методом атомно-абсорбционной спектрометрии исследован микроэлементный состав прикорневого слоя почвы и зольного остатка травы ортилии однобокой в различные фенофазы формирования растения. Установлено, что на состав почвы непосредственное влияние оказывают процессы биологического накопления, в результате чего в поверхностных почвенных горизонтах и траве в большей степени аккумулируются соединения Cu, Zn, Fe и Mn. Содержание элементов в зольном остатке сырья демонстрирует статистически достоверные различия по As, Sb, Hg, Cd, Pb, Mo, Co, Ni и Cr, что свидетельствует об аэротехногенном и водомиграционном их поступлении. Выявлена тенденция накопления суммы флавоноидов с 3-й декады июня по 2-ю декаду сентября (max — фаза одревеснения побегов), после чего происходит постепенное уменьшение их количества (min — фаза зимнего покоя). Максимальное содержание арбутина наблюдается в фазу массового цветения, после чего оно резко уменьшается, достигая своего минимума в фазу одревеснения побегов. Ингибирование биосинтеза физиологически активных соединений протекает в присутствии соединений As, Sb, Pb, Cd, Hg, Fe и Zn (по арбутину); Mo (по арбутину, сумме флавоноидов); Ni (по сумме флавоноидов).
Оценка антиоксидантной и антирадикальной активности экстракта травы Astragalus vulpinus в условиях информационного стресса
Authors: Цибизова А. , Сергалиева М. , Башкина О. , Самотруева М.
Published: July 2023

Изучено влияние экстракта травы Астрагала лисьего (Astragalus vulpinus Willd.) на активность окислительной модификации липидов и белков в сыворотке крови белых крыс в условиях информационного стресса. Информационный стресс моделировали формированием пищедобывательного поведения в многоальтернативном лабиринте. Процессы липидной пероксидации оценивали при спектрофотометрическом измерении в сыворотке крови диеновых конъюгатов, исходного уровня ТБК-реактивных продуктов, скоростей спонтанного и индуцированного аскорбатом и ионами железа перекисного окисления липидов. Для определения степени перекисного окисления белков в сыворотке крови применяли метод, основанный на реакции взаимодействия окисленных аминокислотных остатков белков с 2,4-динитрофенилгидразоном. О состоянии антиоксидантной защиты судили по активности каталазы и супероксиддисмутазы. Установлено, что экстракт травы Астрагала лисьего проявляет выраженные стресс-протекторные, антиоксидантные и антирадикальные свойства в отношении показателей липидной пероксидации и окислительной модификации белков, а также каталазной и супероксиддисмутазной активности в сыворотке крови белых крыс в условиях информационного стресса.
Биологически активные вещества и противовоспалительные свойства сухого экстракта из надземной части Panzerina lanata (L.) Sojak (lamiaceae) при экспериментальном эндометрите
Authors: Корнопольцева Т. , Ботоева Е. , Шурыгина Ю. , Корнопольцева Л.
Published: July 2023

Эффективность препаратов из панцерины шерстистой объясняется богатым химическим составом БАВ. Доказано наличие (+)-катехина, (—)-эпигаллокатехина галлата, кверцетина, галловой, кофейной, хлорогеновой и линолевой кислот, рутина, апигенина, стахидрина, b-каротина в экстракте. Настои и отвары панцерины обладают седативными, тромболетическими, антибактериальными и противовоспалительными свойствами. Испытуемый экстракт благоприятно влиял на показатели остроты воспалительного процесса в крови у животных с эндометритом. Скорость оседания эритроцитов при применении испытуемого фитоэкстракта была в 1,2 раза ниже, чем в контрольной группе, на 7-е сутки; в 1,6 раза на 14-е и 21-е сутки. Количество лейкоцитов при лечении панцериной было ниже, чем в контрольной группе животных, в среднем в 1,2 раза на всех сроках наблюдения. Патоморфологическим исследованием и оценкой динамики изменения показателей активности воспалительной реакции доказана фармакотерапевтическая эффективность применения сухого экстракта из надземной части панцерины шерстистой при экспериментальном эндометрите.
Транссредовой переход макроэлементов по цепочке «почва – лекарственное растительное сырье – водные извлечения»
Authors: Дьякова Н.
Published: July 2023

Представлены результаты экспериментального изучения особенностей транссредового перехода макроэлементов по цепочке «почва – лекарственное растительное сырье (ЛРС) – настои и отвары». В качестве объектов исследования использовали фармакопейные виды ЛРС: листья крапивы двудомной и подорожника большого; цветки пижмы обыкновенной и липы сердцевидной; траву пустырника пятилопастного, полыни горькой, тысячелистника обыкновенного и горца птичьего; корни лопуха обыкновенного и одуванчика лекарственного. Макроэлементный состав образцов изучали масс-спектроскопическим методом после кислотно-микроволнового разложения. Макроэлементы составляют более 84 % элементного комплекса ЛРС. Для всех изучаемых видов сырья к сильно накапливаемым макроэлементам отнесены калий и фосфор. Макроэлементам принадлежит наибольшая доля в общей сумме элементного комплекса водных извлечений — 94,95 – 98,99 %. Показано, что сильно накапливаемые растениями элементы переходят из почв в водные экстракты наиболее эффективно. Степень перехода калия варьировала от 48,57 до 162,43 %, фосфора — от 90,45 до 279,45 %. Элементы, отнесенные в изучаемом ЛРС к группе среднего захвата, также достаточно эффективно переходили по цепочке: доля магния, мигрирующая из почв в настои и отвары, составила от 7,70 до 46,36 %, кальция — от 3,77 до 30,01 %. Наибольшая степень перехода натрия отмечена для отваров корней лопуха обыкновенного — 91,61 %, корней одуванчика лекарственного — 21,45 %, настоев травы горца птичьего — 19,72 %, для остальных водных извлечений варьировала от 1,08 до 7,13 %. Богатый макроэлементный состав изучаемого ЛРС, а также водных извлечений из него может быть использован в медицинской и фармацевтической практике для коррекции физиологических норм содержания макроэлементов в организме человека.
With the Eyes of an Artificial Angel: Benjamin and Adorno Reading Kafka
Authors: Graf Stephanie
Published: July 2023

Adorno and Benjamin’s common intellectual project has been labeled, by Adorno, an Inverse Theology. This re-translation of theology into it’s metaphysical truth contents can be only fully comprehended by taking into account their position towards the work of art. In this article, I locate the place where the categorical framework of “inverse theology” is displayed in a most complete manner in the discussion of Kafka’s prose and extrapolate the outline of an Inverse theology from Adorno and Benjamin’s readings of some of his most famous texts.
Plum Village: From Settlement on a Modest Local Scale to Global Communication Network
Authors: Dorbaire Benjamin
Published: July 2023

Founded in the countryside an hour from Bordeaux, France, by Thích Nhất Hạnh, known for his engaged and modern Buddhism, Plum Village is famous throughout the world for its mindfulness meditation retreats. Although many studies have been carried out on Thích Nhất Hạnh’s history and spirituality, none has addressed the question of the territorial implantation of Plum Village on a local scale, nor the processes of the worldwide diffusion of its network. After presenting the context of the penetration of Thích Nhất Hạnh’s teaching in the West, I explore the establishment of an exogenous religious community in the French countryside in terms of otherness and analyse the communication at play in the process of integration into the local scale in its municipalities in New Aquitaine, and then look at the strategy and means of communication put in place to to federate and expand its network on a global scale.