bluuebunny/crossref_metadata_2025 huggingface dataset:
VARIAÇÃO RADIAL DA DENSIDADE E ESTABILIDADE DIMENSIONAL DA MADEIRA DE TAUARI (Couratari oblongifolia Ducke & R. Knuth.)
Authors: Bozi Lurdes Dadalto , Mascarenhas Adriano Reis Prazeres , Melo Rafael Rodolfo de
Published: March 2022

A madeira é utilizada para movelaria, confecção de painéis e construção civil. Contudo as espécies utilizadas restringem-se a um pequeno grupo que é intensamente explorado, isto oferece risco à disponibilidade dessas espécies nos maciços florestais. Dessa forma é necessária a realização de estudos em relação a espécies menos exploradas para a inclusão das mesmas no mercado. Objetivou-se caracterizar a variação radial das propriedades física da madeira de tauari. Foram utilizadas toras de árvores de tauari, a partir das quais confeccionou-se 120 corpos de prova, submetidos à saturação, secagem e aclimatação, para obtenção de dados para os cálculos de densidade aparente (?a) e básica (?b), porosidade (?), contrações lineares (?l, ?t e ?r) e volumétrica (?V) e o coeficiente de anisotropia (T/R). A madeira foi caracterizada como moderadamente pesada (?b = 0,68 g cm-3), com tendência moderada à empenamentos e baixo coeficiente de anisotropia (<1,4), indicando que o material tem boa estabilidade dimensional e pode apresentar-se como alternativa às espécies intensamente exploradas, pois é encontrada em grande parte da Amazônia.
NARRATIVA DE VÍCTIMAS, IMPUNIDAD Y RELIGIOSIDAD DE LOS SECTORES MEDIOS EN URUGUAY: POSIBLES IMPUGNACIONES AL CAMPO DE LA MEMORIA Y LOS DERECHOS HUMANOS
Authors: MONTEALEGRE Natália
Published: March 2022

This article delves into some aspects of the relationship between impunity, middle sectors and religion in Uruguay, based on the public narrative of a group of disappeared detainees, bestselling author, gestalt therapist and Uruguayan neochamán. Its production of an autobiographical nature is of interest, because it allows us to enter into some dilemmatic aspects that challenge the common sense around concepts of memory and justice, shared in the field of memory and human rights, from a perspective that provides insight into how it can impact in different areas the ethos of individual comfort. Written in the context of a world pandemic, this text contributes to a reflection on the potential consequences of the development of universes of meaning on the pillars of individualism and autonomy, and their potential opposition to the universality of human rights. At the same time, it highlights the intersection between religion and politics in the Southern Cone through the narrative of a victim -member of the second generation-, who builds a biographical project that makes possible the formation of a happy family.
High-fat Diet Increases Sprague-Dawley Corticosterone Blood Levels with Nominal Change in Adrenocorticotrophic hormone (ACTH) Level with Signs of Increased Mesenteric Adiposity
Authors: Azwan Khairil , Mona Resni , Firdous Jannathul , Sari Dina Keumala , David Pamela Rosie , Muhamad Noorzaid
Published: March 2022

BACKGROUND: Corticosterone is a common hormone in research involving rodents as it is used to indicate and measure stress levels. It was widely reported that certain dietary habits and components induce Hypothalamic-Pituitary-Adrenal (HPA) axis activity, with corticosterone found in the bloodstream. Chronic corticosterone presence can portray signs and symptoms of certain endocrine. Certain food and chemicals were found to alter HPA axis activity leading to dysregulation of the HPA axis. Earlier studies have shown enhancement of the HPA axis to produce more glucocorticoids by an unbalanced diet. This study aims to shed more light on this subject.METHODS: Sprague Dawley rats were divided into five groups of seven each and were fed five respective diets (control, high-fat, high-protein, high-sugar, and high-starch), with tap water as drinking water ad libitum. After eight weeks, the rats were euthanized, blood was collected, and serum harvested and kept for analysis. Mesenteric fat was identified, harvested, and stained with hematoxylin and eosin (H&E) and set for viewing under light microscope. The hormones of interest which is adrenocorticotropic hormone (ACTH) and corticosterone was extracted from the blood, to be processed accordingly and quantified using the High-Performance Liquid Chromatography (HPLC) with photodiode array (PDA) analysis technique.RESULTS: The results showed an increase in Sprague-Dawley corticosterone blood levels with a nominal change in ACTH level. Advanced hypertrophy was observed in mesenteric adipose tissue in the high-fat diet group compared to the other diet groups.CONCLUSION: This study confirms the negative effect of a high-fat diet on health from a hormonal and adipocyte perspective. A high-fat diet was found to instigate the HPA axis and influence blood corticosterone level.KEYWORDS: adrenocorticotrophic hormone, ACTH, corticosterone, mesenteric fat, diet
The Difference Levels of Hepcidin and Interleukin-6 between Obese and Non-Obese Type 2 Diabetes Mellitus
Authors: Maherdika Mabruratussania , Samsuria Indranila Kustarini , Hendrianingtyas Meita , Widyastiti Nyoman Suci , Rahayu Muji
Published: March 2022

BACKGROUND: Inflammation occurs in chronic diseases such as type 2 diabetes mellitus (DM). Insulin resistance and inflammation in type 2 DM with obesity can increase interleukin (IL)-6, causing an increase in hepcidin synthesis in the liver. Increased inflammation can exacerbate the course of type 2 DM. This study aims to prove that there are differences in the levels of hepcidin and IL-6 between obese and non-obese type 2 DM.METHODS: This cross-sectional study was conducted on 61 patients with type 2 DM, consist of 22 male and 39 female with an age of more than 40 years. Type 2 DM subjects were obtained from a doctor's diagnosis and were divided into obese and non-obese groups based on body mass index (BMI). Hepcidin and IL-6 levels were examined using the Enzyme-Linked Immunosorbent Assay (ELISA) principle. The data were analyzed using an independent t-test and Mann-Whitney test.RESULTS: The mean level of hepcidin in the obese with type 2 DM group was 25.32±11.54 ng/mL, and non-obese was 11.94±5.31 ng/mL. The median level of IL-6 in the obese with type 2 DM group was 11.9 (5-61) pg/mL, and non-obese 4.8 (1.5-9.8) pg/mL. There was a significant difference in hepcidin and IL-6 levels between the obese and non-obese groups (p=0.000).CONCLUSION: Hepcidin and IL-6 levels in the obese group with type 2 DM were higher than non-obese group.KEYWORDS: type 2 diabetes mellitus, obesity, hepcidin, interleukin-6
Feministyczne poglądy i patriotyczna działalność. Aleksandra Piłsudska w orbicie wielkiej polityki
Authors: Sikorska-Kowalska Marta
Published: March 2022

Aleksandra Szczerbińska, wieloletnia partnerka, a od 1921 roku żona Józefa Piłsudskiego, matka dwóch jego córek, rozpoczynała swoją karierę w Organizacji Bojowej PPS. Zajmowała się kolportażem broni oraz organizacją kobiecych oddziałów bojowych. Po odzyskaniu przez Polskę niepodległości zebrała i wydała drukiem wspomnienia swoich współtowarzyszek broni. We pamiętnikach wielokrotnie podkreślała swoje feministyczne poglądy. Ich analiza a także i patriotyczna postawa stały się przedmiotem krótkich rozważań zawartych w artykule.
Percepciones del cambio climático y el desarrollo sostenible dentro y fuera de la academia en Cusco, Andes peruanos
Authors: Weibel Marianne Claire
Published: March 2022

El cambio climático y el desarrollo sostenible son conceptos bien conocidos, pero sus percepciones pueden variar considerablemente entre comunidades académicas y no académicas en contextos interculturales. La presente investigación examina las relaciones e interrelaciones entre cambio climático y desarrollo sostenible a través de la evaluación comparativa de una comunidad suburbana y una universidad local cercana dentro de los Andes centrales (Cusco, sur del Perú). El objetivo principal es analizar los diferentes puntos de vista de ambas comunidades determinados por contextos socioculturales e impactos del cambio climático específicos. Un análisis temático que apunta a un conjunto diverso de características climáticas y socioeconómicas permite identificar ocho afirmaciones y veinte temas relacionados con el cambio climático y el desarrollo sostenible. Los resultados de ambos grupos revelan una fuerte diversidad de cosmovisión, evidenciada por el hecho de que la comunidad andina está más orientada hacia problemas —enfocando los aspectos negativos del cambio climático— mientras que la comunidad académica apunta a soluciones colectivas. Sin embargo, ambos grupos de entrevistados también comparten percepciones comunes, en particular sobre el manejo de los residuos sólidos. El análisis comparativo de las percepciones académicas y no académicas peruanas en Cusco ofrece una mirada transversal sobre los impactos locales del desarrollo nacional y global. Además, este estudio proporciona conocimientos transferibles para abordar la sostenibilidad a largo plazo de los países de bajos y medianos ingresos, hacia la transformación de ciudades y comunidades inclusivas y más resilientes como parte del camino hacia los Objetivos de Desarrollo Sostenible.
Effect of Moisture Conservation Practices on Growth and Yield of Pearlmillet [Pennisetum glaucum (L.) R. Br. emend Stuntz] Hybrids
Authors: Choudhary Sheeshpal , Yadav L.R. , Shivran A.C. , Choudhary Meena , Bana Ramesh Chand , Lal Babu , Daroga Shiv Prasad
Published: March 2022

Background: A field experiment was conducted under loamy sand soil during two consecutive kharif seasons of 2018 and 2019 at Agronomy farm, S.K.N. College of Agriculture, Jobner, Jaipur to find out the best moisture conservation practices on growth and yield of pearlmillet [Pennisetum glaucum (L.) R. Br. emend Stuntz] hybrids. Methods: Hybrids viz., RHB-173, RHB-177, MPMH-17 and HHB-67 in main plots and moisture conservation practices viz., control, dust mulch, straw mulch, plastic mulch and seed line mulching of FYM in sub plots were tested using split plot design replicated four. Result: The results further indicated that hybrid RHB-173 being at par with RHB-177 significantly higher plant height, dry matter accumulation, yield attributes, grain yield (2097 kg/ha), stover yield (5500 kg/ha) and biological yield (7597 kg/ha) over MPMH-17 and HHB-67. Result showed that application of plastic mulch recorded significantly increased the plant height, dry matter accumulation, yield attributes, grain yield (2145 kg/ha), stover yield (5620 kg/ha) and biological yield (7764 kg/ha) compared to other moisture conservation practices in both the years of experimentation as well as on pooled basis.
Defending The Country on The Movement of The Younger Generation in Lafran Pane’s Perspective
Authors: Azizah Umi , Djono Djono , Musadad Akhmad Arif , Ariwidodo Eko
Published: March 2022

This research discusses the defensive attitude of the younger generation, especially the younger generation of muslims, based on Lafran Pane’s thoughts. Lafran Pane is one of the hero figures in Indonesia who had a significant influence on maintaining Indonesia's independence. This research aims to determine and understand Lafran Pane’s thoughts on defending the country by the younger generation, especially the younger generation of muslims in Indonesia. The method used in this research is the descriptive qualitative research method. This study found that Lafran Pane emphasized the young age to maintain Indonesian independence by returning to the Islamic teachings and practicing them in all activities. He has reformed thoughts in various fields, created a new education system, made Islamic and Indonesian-ness the starting point for the movement.
The Responses of The Islamic Higher Education Students Against The Interpretation of The Quran’s Violent Verses and Hadith in Riau
Authors: Zarkasih  , Permana Niki Dian , Nawi Aliff , Vebrianto Rian , Thahir Musa
Published: March 2022

The understanding of spiritual doctrine becomes the reason, and it causes an escalation in violence in the name of religion. Misinterpreting the Qur'an verses causes the doer to legalize the violence they do. This article presents the responses of Islamic higher education students in Riau Province and Riau Islands about the interpretation of violent verses in the Qur’an and Hadith. The sample consisted of 251 students from UIN Sultan Syarif Kasim in Riau, STAIN Bengkalis, and STAIN Abdurrahman Saleh in Riau Islands using a random sampling technique. Using descriptive analysis, the students’ responses against the interpretation of violent verses were categorized as fairly positive at 61%. It indicates that 39% of the students had a negative response. Hence, this study recommends the importance of efforts to “neutralize” the students’ understanding of the three Islamic higher education in Riau to prevent their tendency to have harsh or even radical understanding and responses.
Influencia de la adicción a redes sociales sobre el bienestar psicológico en estudiantes universitarios de Lima Metropolitana
Authors:   ,   Universidad San Ignacio de Loyola, Padin Berdejo Fanny
Published: March 2022

El objetivo del estudio fue determinar si existe una influencia significativa de la adicción a redes sociales sobre el bienestar psicológico de los estudiantes universitarios de Lima Metropolitana. La muestra estuvo conformada por 323 estudiantes universitarios (76.2% Mujeres), con un rango de edad de entre los 18 a 30 años (M = 24.3; DE = 4.11). Los instrumentos utilizados fueron el Cuestionario de Adicción a las Redes Sociales (ARS) y la Escala de Bienestar Psicológico para Adultos (BIEPS-A). Los resultados revelaron que la dimensión obsesión por las RS influye de forma inversa y significativa sobre la dimensión aceptación/control de situaciones y vínculos sociales del BP y la dimensión falta de control personal del uso de las RS de la ARS influye de forma inversa y significativa sobre la dimensión aceptación/control de situaciones, autonomía y proyectos del BP. Por lo que se concluye que solo algunas dimensiones de la ARS es un predictor significativo de las dimensiones del BP.
Insights on the disruption of glucose metabolism and hepatic insulin resistance induced by hepatitis C virus
Authors: Solís-Muñoz Pablo , Berlana Ángela , del Pozo-Maroto Elvira , Domínguez-Alcón Lucía , Elbouayadi Liliam , García-Monzón Carmelo , González-Rodríguez Águeda
Published: March 2022

Hepatitis C virus (HCV) is still considered as a major public health problem because in 2015 around 71 million people were chronically infected worldwide. It is important to note that chronic HCV infection is a systemic disease that is associated with diverse extrahepatic disorders including insulin resistance and type 2 diabetes mellitus. The discovery of new direct-acting antiviral agents (DAAs) has become a huge advance in the treatment of HCV infection. The complex interplay between HCV and glucose metabolic pathways remains to be fully elucidated, but it is becoming clearer that elimination of chronic HCV infection halts the progression of liver disease, but more evidence is still needed to better understand how successful antiviral treatment influences insulin resistance and other abnormalities of glucose metabolism linked to HCV infection. This review provides a comprehensive overview of the glucose metabolism disturbances related to chronic HCV infection, highlighting the new insights into the molecular basis of insulin resistance induced by HCV and the mechanisms underlying the reversion of this metabolic disorder by DAAs.
Stylistic variability of the Abashevo ceramics: on the problem statement
Authors: Panteleeva S.E.
Published: March 2022

The article presents the results of generalization and systematization of available data on household cera-mics of the Abashevo cultural-historical community. This cultural formation extended through the forest-steppe zone of the European part of Russia from the Don Region to the Trans-Urals. The obtained radiocarbon dates comprise the period of 2200–1800 cal BC. The study is based on published information about collections of 33 settlements located in different parts of the vast Abashevo area. The following set of features was considered for comparison: tempering materials, methods of surface treatment, shapes of vessels, main ornamental elements and techniques of their application, and key ornamental compositions. As a result of the analysis, the ceramic collections were divided into seven groups, which can be combined into four large stylistic zones for the similarity of ornamental and morphological characteristics: Don-Volga, Trans-Volga, Cis-Urals, and Trans-Urals. The distri-bution areas of stylistic zones apparently correspond to the areas of residence of the major local groups of the Abashevo population. It is noted, that addressing the issues of chronological correlation of separate districts and the sites within them is impossible without the implementation of a large-scale program of radiocarbon dating. Stylistic variability of the Abashevo pottery was considered within the framework of the information exchange theory of H.M. Wobst. It has been concluded, that the inhabitants of the Cis-Ural settlements, who had the most diverse and expressive ceramic complex, were involved in active interactions with communities of other regions. A need to demonstrate the group identity was reflected in the appearance of pottery made in a specific style characteristic only for this group. At the same time, external connections initiated diffusion of foreign stylistic features that re-sulted in increased internal variability of wares. The main reason for the intensive cultural contacts was apparently the specialization of the Cis-Ural communities on metal production. The uniformity and simplicity of pottery from the Don-Volga settlements suggest a high degree of internal integration of the local population, and as a conse-quence — the absence of necessity for marking the social boundaries between the groups. The external contacts were probably weak, or irregular, and they did not lead to significant changes in the structure of society and diffu-sion of new stylistic elements. Pottery of the Trans-Ural group appears rather independent, although some of the vessels have specific features of the Abashevo pottery tradition of the western regions. It can be assumed that the Trans-Ural settlements were occupied by a group of people that separated from the main Abashevo massif and advanced beyond the Ural Mountains in search of sources of high-quality ore raw materials. Apparently, these sites are the latest, and they are synchronous to the Sintashta antiquities.
The burial Ogonyok in the middle Lena River region: a new site of the Bel'kachi Culture
Authors: Alekseev A.N. , Dyakonov V.M. , Solovyova E.N. , Nikolaev E.N. , Boeskorov G.G.
Published: March 2022

The article presents the results of a comprehensive study of the Ogonyok burial, discovered and investigated in 2016 in the city of Yakutsk, Central Yakutia, in the middle reaches of the Lena River. The purpose of the study was to determine its cultural and chronological characteristics, to identify the features of the funeral rite and spe-cifics of the accompanying grave goods. In addition to historical and archaeological methods, the methods of tra-sological analysis of stone tools, radiocarbon dating and date calibration, isotope analysis of human and animal bone collagen, and determination of the species composition of the fauna that was part of the burial equipment were used. The burial place was destroyed during land works, as such, only part of the accompanying equipment and osteological material was preserved for the analyses. Excavations of the remains of the burial were carried out, which made it possible to determine approximately its orientation, the position of the deceased and the depth from the day surface. Similarities to the accompanying goods, which included a flint core and three blades, an arrowhead, polished adze, bone composite arrowhead with a blade in the groove, anthropomorphic figurine from a mammoth tusk, fragments of a bone polisher and a needle, as well as faunal remains, were found in the com-plexes of the Bel'kachi Neolithic Culture of Northeast Asia of the end of the 5th–3rd mil. BC. Further analogies were identified in the synchronous Neolithic cultures of the Baikal, Transbaikalia, Lower Amur region, Primorsky Krai and Chukotka. The funeral ritual of filling the grave with ocher also brings the Ogonyok burial closer to other Bel'kachi cemeteries. Paleozoological analysis has shown that bones of lynx, wild reindeer and geese were pre-sent in the burial. Four AMS radiocarbon dates were obtained from human and animal bones, which attribute the burial in the first quarter of the 4th mil. BC. An interesting fact was the identification of an offset in the age of hu-man bones relatively to the age of animal bones, the former being approximately 200 years older, which is appa-rently associated with freshwater reservoir effect. Analysis of stable carbon and nitrogen isotopes demonstrated that the human diet was based on meat food, as well as, apparently, fish products, with a minor inclusion of wild plants. The burial of Ogonyok is one of the few “pure” sites of the Bel'kachi Neolithic Culture in Yakutia.
Demographic Variables Impact on Individual Investment Return
Authors: Huq Khan Md. Fazlul , Ahmed Fakrul
Published: March 2022

The study tries to find out the impact of investors demographic variables on the return from the stock market. The data has been collected from the brokerage and Marchant banks for individual investors investments, return and demographic characteristics. The research covers the period from 2009 to 2021 and have a decade long enough to identify the trend. The structural break in the data also been adjusted to avoid any kind of endogeneity. The regression results suggest that demographic variables affect the investment pattern and beta return for the investors. the demographic variables such as education, location and experience have positive links with the beta whereas age and income show negative association. The education, income and experience variables are also found to be significant in the empirical analysis.
Inovasi Gamifikasi Pada Pembelajaran Matakuliah Pengembangan Media Sederhana
Authors: Ariani Diana , Prawiradilaga Dewi s. , Fatharani Wasetya
Published: March 2022

Learning activities with fully online learning during the pandemic caused student saturation in carrying out learning routines. Especially on less desirable materials. For this reason, learning innovations are needed to facilitate student learning needs, one of which is gamfication. This study aims to produce Gamification in Pengembangan Media Sederhana course at the Education Technology Study Program, State University of Jakarta. Study. This development research follows the Rapid Prototyping model procedure by Tripp and Bichelmeyer, which has 5 stages, namely Assess Needs and Analyze Content, Set Objectives, Construct Prototype (design), Utilize Prototype (research), and Installing and Maintain System. Evaluation with an open survey obtained user interest with high gamification, and more adjustments are needed in the elements used.

 

Abstrak

Kegiatan pembelajaran dengan fully online learning selama masa pandemi menyebabkan kejenuhan pada mahasiswa dalam melaksanakan rutinitas pembelajaran. Terlebih pada materi yang kurang diminati. Untuk itu perlu inovasi pembelajaran dalam memfasilitasi kebutuhan mahasiswa belajar, salah satunya dengan Gamfikasi. Penelitian ini bertujuan menghasilkan Gamifikasi pada matakuliah Pengembangan Media Sederhana di Program Studi Teknologi Pendidikan Universitas Negeri Jakarta. Penelitian. Penelitian pengembangan ini mengikuti prosedur model Rapid Prototyping oleh Tripp dan Bichelmeyer, yang memiliki 5 tahap, yaitu Assess Needs and Analyze Content, Set Objectives, Construct Prototype (design), Utilize Prototype (research), dan Installing and Maintain System. Evaluasi dengan survey terbuka diperoleh minat pengguna dengan gamifikasi yang tinggi, dan perlu penyesuaian lebih dalam elemen-elemen yang digunakan.
Pengembangan Mobile Learning dengan Metode Studi Kasus untuk Mata Pelajaran PPKn Kelas VI di SDN Telajung 01
Authors: Dian Rosdiana Noor  , Siregar Eveline , Chaeruman Uwes Anis
Published: March 2022

Penelitian pengembangan ini dilakukan dengan tujuan menghasilkan sebuah media pembelajaran berupa mobile learning dengan metode studi kasus untuk mata pelajaran PPKn kelas VI. Mobile learning ini diharapkan dapat memfasilitasi belajar peserta didik dan membentuk karakter yang sesuai nilai-nilai Pancasila pada diri peserta didik. Pengembangan ini menggunakan model Rapid Prototyping yang terdiri dari lima tahap, yaitu asses needs and analyze content, set objectives, construct prototype, utilize prototype, install and maintain system. Evaluasi pada penelitian pengembangan ini terdiri dari review ahli (ahli materi dan ahli media) dan uji coba pengguna yaitu uji coba satu-satu, kelompok kecil, dan evaluasi hasil belajar. Evaluasi tersebut melibatkan 1 orang ahli materi, 1 orang ahli media, dan 12 orang pengguna. Hasil review ahli diperoleh skor rata-rata ahli materi sebesar 3,68 (sangat baik) dan ahli media sebesar 3,4 (sangat baik). Pada tahap evaluasi uji coba satu-satu diperoleh skor rata-rata sebesar 3,28 (sangat baik) dan pada uji coba kelompok kecil sebesar 3,34 (sangat baik). Berdasarkan hasil tersebut dapat dinyatakan bahwa mobile learning dengan metode studi kasus ini memiliki kualitas “sangat baik” dan dapat digunakan untuk media pembelajaran dengan dilakukan penyempurnaan lebih lanjut.
PENGENALAN RAMBU LALU LINTAS DENGAN MENGGUNAKAN FUZZY INFERENCE SYSTEM (FIS) MAMDANI
Authors: Syafrika Deni Rizki  , Tri Monarita Johan
Published: March 2022

Rambu-rambu lalulintas merupakan bagian dariperlengkapan jalan yang memuat lambang, huruf, angka, kalimat atau gabungan diantaranya, yang berfungsi untukperingatan atau pemberitahuan bagi pemakai jalan. Banyak kecelakaan yang terjadi dijalan karenapelanggaran lalulintas, ini di karenakan banyak masyarakatyang belum mengetahui arti atau maksud dari rambu-rambu yang ada di jalan, dan masyarakat kurang pahamarti dari rambu-rambu lalulintas yang terdapat dijalan,juga di karenakan sosialisasi yang kurang terhadap masyarakat mengenai pentingnya mematuhi rambu-rambu lalulintas.Rumusan masalah dalam penelitian ini adalah bagaimana membuat suatu aplikasi tentang rambu lalu lintas untuk meminimalisir pelanggaran lalu lintas dan sebagai sarana investasi jangka panjang dengan memperkenalkan rambu lalu lintas di pendidikan usia dini.

 

Traffic signs are part of road equipment containing symbols, letters, numbers, sentences or a combination thereof, which functions as a warning or notification for road users. Many accidents that occur on the road are due to traffic violations, this is because many people do not know the meaning or purpose of the signs on the road, and people do not understand the meaning of traffic signs on the road, also because of the lack of socialization to the public regarding the importance of obey traffic signs. The formulation of the problem in this study is how to make an application about traffic signs to minimize traffic violations and as a means of long-term investment by introducing traffic signs in early childhood education.
PENGABDIAN MASYARAKAT BERBASIS MODERASI BERAGAMA: STUDI IMPLEMENTASI KKN NUSANTARA IAIN PONOROGO TAHUN 2021 DI DAERAH 3 T, KONAWE, SULAWESI TENGGARA
Authors: Virdaus Dony Rano , Khaidarulloh Khaidarulloh
Published: March 2022

Artikel ini fokus mendiskusikan tentang bagaimana implementasi nilai-nilai moderasi ditanamkan melalui kegiatan akademik di ranah perguruan tinggi melalui kegiatan KKN. Studi ini bertujuan untuk menunjukkan bahwa negara, selain menjadikan isu moderasi beragama sebagai arus utama dalam membangun karakteristik keberagaman, juga melakukan terobosan demi optimalisasinya. Penelitian deskriptif ini didominasi oleh data field research yaitu wawancara dengan peserta KKN Nusantara Moderasi Beragama yang berhasil melakukan kegiatan pengabdian masyarakat di  Mulyasari, Mowila, Kabupaten Konawe Selatan, Sulawesi Tenggara, juga diperkaya oleh data skunder berbentuk studi literatur. Hasil menunjukkan bahwa KKN Nusantara berbasis Moderasi Beragama yang dilakukan oleh peserta merupakan terobosan penyemaian nilai-nilai moderasi yang saat ini menjadi salah satu isu aktual di level Kementerian Agama di tengah maraknya isu intoleransi dan disintegrasi antar agama. Instrumen KKN sebagai media desseminasi nilai-nilai moderasi beragama memberi ruang baru bagi mahasiswa dalam memahami dinamika keberagamaan yang rawan dengan isu-isu intoleransi dewasa ini.
Impacto social, económico y de mercado como consecuencia del Covid-19 en tiendas de barrio en el sur de Bogotá
Authors: Rico-Pencue Brallan Exneider , Vera-Castillo Johan Sebastián , Bohórquez-Arévalo Luz Esperanza
Published: March 2022

El objetivo del artículo es identificar el impacto social, económico y de mercado que ha tenido la pandemia generada por el Covid-19 en las tiendas de barrio ubicadas en las localidades del sur de Bogotá. Así mismo, busca establecer cuáles han sido las estrategias que los tenderos han implementado para seguir en el mercado. Con este fin se realizó una caracterización de distintos establecimientos comerciales determinando los elementos clave que influyen en su actividad comercial, además de los elementos sociales del entorno, según los productos que ofrecen, teniendo en cuenta que muchos de estos comerciantes cuentan con una gran variedad de productos en su portafolio. Posteriormente, se planteó la mayor cantidad de indicadores posibles que sirvieran para describir la situación de estos establecimientos; estos indicadores fueron validados utilizando la metodología de panel de expertos. Una vez validados se construyó una encuesta con el fin de medir el impacto de la pandemia en tres momentos de tiempo definidos, antes de la pandemia, durante el aislamiento y durante la activación económica. En el estudio se concluye que los tenderos de esta zona no han desplegado estrategias para afrontar la crisis y se evidencia la importancia del acompañamiento de los productores de consumos masivos, el Gobierno y la academia para el despliegue de estas actividades.
Capital humano y pobreza monetaria departamental en Colombia durante el periodo 2010-2017
Authors: Guerrero-Jiménez Andrea
Published: March 2022

Este trabajo evalúa la relación entre la dotación de capital humano —educación, salud y nutrición— y la pobreza en Bogotá, junto con veintitrés departamentos de Colombia durante el periodo 2010-2017. La estimación econométrica se realiza con la metodología de datos panel estáticos, particularmente de un panel corto. Los resultados sugieren que la educación es una variable significativa para explicar los niveles de pobreza, especialmente la educación secundaria y superior. Se concluye que un incremento en un 1 % de la cantidad de personas que poseen educación secundaria como proporción de la población económicamente activa, disminuye la incidencia de la pobreza monetaria en un 0,43 %; mientras que, un incremento en un 1 % de la cantidad de personas que poseen educación superior como proporción de la población económicamente activa, disminuye la incidencia de la pobreza monetaria en un 0,39 %. Por último, se evidencian las sustanciales disparidades en términos de pobreza y capital humano entre Bogotá y los veintitrés departamentos, siendo el departamento del Chocó el escenario con mayor pobreza y menores dotaciones de capital humano y Bogotá el escenario con menor pobreza y mayores dotaciones de capital humano.
A Porothermoelastic Model Considering the Dynamic Temperature-Perturbation Boundary Effect for Borehole Stability in Fractured Porous Rocks
Authors: Gao Jiajia , Lin Hai , Sun Jin , Chen Xiuping , Wang Huixiang , Liu Xianfeng
Published: March 2022

Conventional drilling design tends to inappropriately predict the mud density required for borehole stability of deep fractured porous rocks, such as shale, tight sandstone, and hot dry rock, because it is treated as a single-porosity case and even introduces the influence of weak plane to cover the effect on the fracture system. When the external loadings are applied, fractured porous rocks naturally display two different poromechanical responses of the matrix system and the fracture system considering respective hydraulic and mechanical properties. Besides, the constant temperature difference between the drilling mud and formation rock is often chosen as a boundary condition to solve the temperature balance equation, and thus the incorrect prediction of temperature variations of fractured rock further leads to inappropriate evaluation of the pore pressure and stress fields considering the thermo-hydromechanical (THM) coupling (porothermoelastic model), since a dynamic temperature-perturbation boundary condition related to the temperature at the borehole wall actually accounts for the circulating effect of the drilling mud. Therefore, this paper first uses the API RP 13D (1995) model in combination with the circulating temperature-fields model of Raymond (Raymond 1969) to obtain a set of fully transient analytical solutions to circulating temperature fields, including the four types of temperature inside the drilling pipe, borehole annulus, at the borehole wall, and formation. Furthermore, under local thermal equilibrium (LTE) condition, one considers the dynamic temperature-perturbation boundary condition and provides semianalytical porothermoelastic solutions to the field variables around a vertical borehole subjected to nonhydrostatic stresses in fractured porous rock with dual porosity and dual permeability. The solutions for field variables are obtained in line with the plane strain assumption. The variables include displacements, stresses, and two pore pressures of the matrix system and fracture system. The model is verified by the analytical solutions in the case of a porous medium with a single-porosity one under LTE condition. The main results show that the dual-porosity medium displays a higher borehole instability potential than the single-porosity one. This increasingly cooling effect increases the higher risk of the tensile transverse fracturing when the constant temperature-perturbation boundary condition chooses a smaller temperature difference than that of the dynamic case at a later time. The drilling mud-pressure window narrows with increasing time when the coupled porothermoelastic model is considered. It suggests that the drilling engineer takes into consideration the dynamic temperature-perturbation boundary effect, fracture spacing, and fracture width into the predrilling design of the time-dependent safe mud-pressure window (SMPW).
The History of Korean Minimally Invasive Spine Surgery Society (KOMISS) and Global Impact on Spine Surgery
Authors: Choi Il , Kim Jin-Sung
Published: March 2022

Korea minimally invasive spine surgery society (KOMISS) celebrated its 20th anniversary this year in 2021. The society was established in 2002 for the purpose of research on novel techniques and instruments in the rapidly developing field of spine surgery, under the leadership of Professor Park, Chun Kun, the first president. Annual meetings have been held every year since. The advanced course focusing on endoscopic surgery was introduced in 2009, while international academic conferences and cadaver workshops have been held since 2012. In 2012, the first textbook was published. In 2015, KOMISS was promoted to an official society by integrating with the Korean Society for Minimally Invasive Spine Surgery, another Korean society for minimally invasive spine surgery (MIS). Additionally, in 2017, the Korean Research Society of Endoscopic Spine Surgery (KOSESS), a research group specialized in spinal endoscopic surgery, was established as its own society. Presently, in the face of the ongoing corona pandemic, there is continuous research efforts through online meetings. For the past 20 years, KOMISS has been educating Korean doctors on MIS surgery through various symposiums and hand on workshops, and has gradually established its ranks and expanded its scope around the world. Most importantly, among the many areas of minimally invasive spinal surgery, KOMISS has developed surgical techniques focusing on endoscopic spinal surgery above all else and has had an unrivaled impact worldwide. Consequently, pioneers and world-renowned surgeons of endoscopic spine surgery in KOMISS have inaugurated the era of endoscopic spine surgery as gold standard of care.
Drug and pesticide usage for sea lice treatment in salmon aquaculture sites in a Canadian province from 2016 to 2019.
Authors: Hamoutene Dounia , Oldford Vanessa , Donnet Sebastien
Published: March 2022

We used 4 years of publicly available data (2016 to 2019) on chemical usage at salmon sites with information on production, stocking, locations and environmental conditions to explore patterns of anti-sea lice treatments in a Canadian province. Results show that sequential chemical treatments are prevalent, emamectin benzoate (EMB) with azamethiphos being the most used combination with a decrease in ivermectin usage. Relatively high rates of usage of EMB per fish biomass may point to potential lice resistance patterns with information needed on mechanisms and local populations. Lower or no chemical usage at some sites indicate less sea lice infestations likely influenced by localized site conditions (coves), and a lessened need for medication due to the usage of cleaner fish and possibly other non-chemical methods (not documented in this report). The year/climate influenced chemical input only in sites with higher treatment levels likely due to effects on sea lice growth and reproduction. Observed differences between years are warmer surface temperature in the fall, a higher freshwater input in spring, and stronger wind conditions for 2017 and 2018 with more medication usage for these two years. The lack of significant effect of site distances calculated in zones of influence based on 24h potential connectivity patterns highlight the need to refine the resolution of hydrodynamic processes.
Asymmetric dimethylation amplifies stress granule assembly via phase separation
Authors: Ruan Ke , Fan Weiwei , Qin Mengtong , Chen Feng , Li Linge , Xu Tian , Zhang Hanyu , Li Yan , Hu Duo-Duo , Gao Shuaixin , Li Ru , Li Jingwen , Wang Weiqian , Hai Zhang , Gao Jia , Liu Xing , Tu Xiaoming , Wu Jihui , He Wei , Li Pilong , Yao Xuebiao , Wong Catherine , Shi Yunyu , Wang Xi-Sheng , Hou Zhong-Huai , Yang Zhenye , Liu Dan
Published: March 2022

Stress granules (SGs) form through phase separation of biomacromolecules to assist cells in resisting environmental stresses. Numbers of SG proteins contain Arg-Gly-Gly (RGG) motifs, indicating their RNA binding ability, and providing a substrate platform for asymmetric dimethylation of arginine (ADMA), whose roles in SG assembly remain unclear. Here, we demonstrated that Caprin1-mediated recruitment of PRMT1 asymmetrically dimethylates RGGs to provide multiple binding sites for TDRD3, a typical ADMA reader, which in turn bridges the multivalent interactions between RGG motifs and RNA to promote phase separation. This process was suppressed by a bivalent inhibitor of TDRD3, eventually inhibiting proliferation more effectively than arsenite treatment alone. Our work reveals the role of ADMA in SG assembly and the potential of targeting condensates for cancer therapy.
Intelligent Transport System using IoT-V2X: Communication Technologies, Security Issues, Challenges and Countermeasures
Authors: Saraswathi Pedada , RAJKUMAR GVS , Rao Patruni Muralidhara
Published: March 2022

The Internet of Things (IoT) has become an essential part of today's human lives. It provides various services in various domains such as large-scale industrial systems, transportation, power grid, agriculture, logistics, smart cities, and related public and private environments. Of late, vehicle-to-everything (V2X) has seen advancements in intelligent transportation to better the 21st century. The convergence of interconnecting IoT sensors with V2X brings numerous advanced services to a large extent. Moreover, the V2X has its features, including capability in object detection, collision warning, hazard warning, traffic information, routing information, optimized solutions, to name a few. Resultantly, V2X technology can significantly enhance the vehicular environment. These advancements in the V2X are expected to bring new challenges to the existing infrastructures. However, providing security to the IoT environments is yet a challenging task. Although various security measures have been imposed to protect these V2X environments, it is still open to adversaries in different security and privacy aspects. Thus, this paper provides an overview of V2X communication technologies, security issues, challenges, and countermeasures. Also, we explore various attacks prevalent to existing solutions. Finally, we provide a comprehensive review of various security solutions imposed on V2X environments.
The potential socio-economic impacts and ecotourism influences for the reintroduction of the White-tailed Eagle on the Isle of Wight
Authors: Jagait Manminder
Published: March 2022

Reintroduction programs for wild animals into the natural environment have been researched and studied where the findings have illustrated main points of discussion. This research paper attempted to explore the reintroduction program currently underway within the Isle of Wight for the white-tailed eagle. By conducting open-ended qualitative interviews with stakeholders across a wide spectrum of industries the findings provide useful information into establishing three main views on the reintroduction program. From those participants totally opposed of this reintroduction project, because they feel this places an enormous amount of strain on the current wildlife to those honourably in favour of the reintroduction of this apex predator because this encourages more wildlife knowledge and to those that decided to remain neutral on the subject matter being investigated.
Body mass index is a mediumiator of the genetic association between STK39 and blood pressure in Mexican women
Authors: Huerta-Chagoya Alicia , Moreno-Macías Hortensia , Ordoñez-Sánchez María Luisa , González-Villalpando Clicerio , Aguilar-Salinas Carlos Alberto , Gamba Gerardo , Sebastián G.-Behn-Eschenburg , Marroquín-Rodríguez Montserrat , Tusié-Luna Teresa , Chávez-Canales María
Published: March 2022

Background
Although obesity causally relates to hypertension, the underlying genetic mechanisms are not completely understood. STK39 gene, encoding the SPAK kinase, associates with both hypertension and body mass index (BMI). In a murine model, we previously showed that the inactivation of SPAK resulted in a hypotensive and obesity-resistant phenotype.
Methods
We analyzed the mediator effect of BMI on the association between STK39 and systolic blood pressure (SBP) in a sample of 2,853 Mexican adults. We also assessed the STK39 expression patterns in human adipose tissue, a relevant tissue determining BMI.
Results
We found that a STK39 locus, tagged by rs6749447 genetic variant, has a positive and significant direct effect on blood pressure in women (B(SE) = 0.073(0.028), P = 0.010), as well as an indirect effect through the BMI (B(SE) = 0.010(0.004), P = 0.024), therefore showing that BMI is a mediator of STK39 and SBP. None of the effects were significant in men (direct effect: B(SE) = 0.030(0.031), P = 0.329; indirect effect: B(SE) = 0.124(0.255), P = 0.626). Additionally, we found that STK39 is expressed in subcutaneous adipose tissue with similar steady-state levels to PPARG and LIPE genes, and its expression is higher in women than in men (P = 0.0008).
Conclusions
Our results shed light on the genetic basis of obesity-induced hypertension and outline a specific locus within STK39 as an important modulator of this process.
Comparative Study Of Growth And HSP70 Gene Expression In Japanese Quails Fed Different Levels Of Black Solder Fly, Hermetia Illucens
Authors: El-Sayed Mohammed A , Hatab M.H , Ibrahim N. S , Assi H.AEM , Saleh H. M , Sayed W.AA , Rumpold B.A
Published: March 2022

Edible insects are considered a promising nutritious, sustainable alternative protein source for feed. The effect of black solder fly (BSF), Hermetia illucens meal on growth performance, heat stress-responses and heat shock protein (HSP70) gene expression in sexed Japanese quail were assessed. The quails were fed on three different diets containing 100% soybean meal (diet A), 50% soybean and 50% BSF meal (diet B) and 100% BSF meal (diet C). Results revealed that overall live body weight, the relative weight of carcass, heart, liver, spleen, bursa of Fabricius, small intestine and sex organs of Japanese quail were significantly increased for diet B and C as compared to diet. The interaction of dietary treatment and heat stress had a significant effect on the diet A group's live body weight, the relative weight of carcass, and measured organs, whereas the diet B and diet C groups had no or the least effect on their traits. Investigating HSP70 gene expression with heat stress exposure in control diet A was 13.215. While, the diet B was expressed of 8.487 with the HSP70 gene. Moreover, the gene expression of the birds fed on diet C were 3.203, respectively. Our findings point to a beneficial role for BSF meal as a quail feed in improving growth performance and combating the negative effects of heat stress exposure on bird growth.
The groundwater environmental effects and health risk assessment in saline-fresh water mixing zone of coastal plain
Authors: Liu Sen , Yang Xiao , Liu Yanan , Jia Chao , Gao Maosheng , Dang Xianzhang
Published: March 2022

The groundwater environment is important to human living in coastal plain. In this study, southern Laizhou Bay (SLB) is chosen as the study area and 47 groundwater samples are collected to analyze groundwater environmental effects and health risk assessment in saline-fresh water mixing zone (SFMZ) of coastal plain. Influenced by saline water intrusion (SWI), K+, Na+, Ca2+, Mg2+, Cl-, SO42- and HCO3- concentration values are exceeded WHO standard value seriously. High-F groundwater is the product in process of SWI, caused by cation exchange, weakly alkaline environment, evaporation and fluorite dissolution. Na+ concentration and a decrease in the Ca2+ concentration can promote further dissolution of fluorite and other F-containing minerals. Based on the health risk assessment method, the average HQ sequence in typical groundwater pollutants is Cl- > F- > NO3-N > Se > Mn > NO2-N > Cu > Pb > Zn > Fe, and the CR sequence caused by carcinogenic heavy metals is Cd > As > Cr. The greatest non-carcinogenic risk to adults and children in the study area is caused by Cl-. Cd is the most important indicator of carcinogenic risk, and its contribution to CR accounts for 74.531%. The regions with high health impacts of carcinogenic pollutants in groundwater are mainly concentrated in the central part of the study area, with the exceeding range of 35.373% for adults and 44.768% for children. Non-carcinogenic pollutants are enriched in SFMZ, which have greater impacts on human body and lead to higher health risks compared with carcinogenic pollutants.