bluuebunny/crossref_metadata_2025 huggingface dataset:
Husserl e a Descoberta da Terra: Prolegômenos para uma Arqueologia do Sentido
Authors: Barroso Gabriel Lago de Sousa
Published: June 2022

No presente artigo, examino a função transcendental do conceito de Terra para a constituição da espacialidade e da temporalidade na fenomenologia tardia de Edmund Husserl. Primeiramente, analiso o problema da bifurcação da experiência entre a apercepção das ciências naturais e a experiência do mundo da vida, mostrando como a epoché das ciências naturais resolve este paradoxo ao impor uma limitação à pretensão de hegemonia do naturalismo sobre a verdade e o conhecimento. A seguir, argumento que a limitação do naturalismo permite uma diferenciação eidética dos fenômenos, estabelecendo a possibilidade de uma análise da espacialidade segundo a relação genética entre corpo (Körper), corpo vivo (Leib) e Terra (Erde). Neste caso, a Terra não é simplesmente um objeto da experiência, mas um elemento pré-subjetivo das condições de possibilidade da experiência. Por fim, mostro as consequências da função transcendental da Terra para a análise da temporalidade e da historicidade. Por um lado, a fenomenologia tardia de Husserl se caracteriza por uma territorialização do sentido, na qual o campo da experiência é enraizado na intersubjetividade de uma pluralidade de territórios organizados em um mesmo espaço terrestre. Território e Terra são horizontes da experiência possível que se encontram em uma relação de coinclusão e entrelaçamento, indicando uma superação da divisão clássica entre natureza e cultura. Por outro, esta territorialização do sentido tem uma consequência importante para a filosofia fenomenológica, uma vez que permite formular o programa de uma arqueologia do sentido.
JAROCHO JAM COMO PATRIMONIO ABIERTO
Authors: Strukelj Pedro , Hernández Simao
Published: June 2022

O artigo apresenta o filho Jarocho, suas características musicais, seu contexto e sua transmissão como exemplo da viagem de uma tradição musical e seu encontro com outras línguas. breve reflexão sobre a chamada música folclórica que tem sido utilizada como padrão de identidades regionais e nacionais, com foco na particularidade de Son Jarocho como experiência dentro e fora do palco. inclui a crônica de uma experiência em que o grupo de tradição familiar do Sul de Veracruz, México “Los Baxin”, durante uma turnê de concertos e oficinas em Barcelona, compartilhou uma jam session com o grupo Fat (Free Arte Três).
Cristianismos no Império Romano: perspectivas historiográficas
Authors: Farias Júnior José Petrúcio , Reis da Silva Graziela , Santana Coelho Viana Loysa Lara
Published: June 2022

Com esse artigo, pretendemos refletir sobre os principais processos históricos que impulsionaram o fortalecimento dos cristianismos no Império Romano. Assim, nossos estudos voltam-se aos principais posicionamentos historiográficos que explicam o êxito do discurso cristão diante de outros movimentos religiosos. Assim, questionamo-nos sobre, como esse movimento de excluídos se tornou a religião oficial de Roma.
OS MÉTODOS DE RESOLUÇÃO ADEQUADA DE DISPUTAS (RAD) SOB O ENFOQUE DA SUSTENTABILIDADE MULTIDIMENSIONAL
Authors: Saticq Junior Joarez Avila
Published: June 2022

Objetivou-se analisar se os métodos de RAD cumprem as dimensões ambiental, econômica, ética, jurídico-política e social da sustentabilidade, consoante proposto pelo doutrinador Juarez Freitas. O principal método de abordagem empregado foi dedutivo, porque, com base em ensinamentos acerca do assunto, demonstrou-se se tais métodos cumprem a sustentabilidade multidimensional. Concluiu-se que os métodos de RAD trazem um olhar diferenciado acerca da aplicação da justiça – vistas mais próximas do direito e da sociedade. E com a aplicação de decisões sustentáveis, não somente na esfera ambiental, mas em outras áreas, há de se reconhecer que os métodos cumprem o princípio da sustentabilidade multidimensional.
DELAÇÃO PREMIADA E SIGILO: ANÁLISE DAS CONSEQUÊNCIAS JURÍDICAS DA DIVULGAÇÃO INDEVIDA DO ACORDO E CONTEÚDO DAS DECLARAÇÕES DO DELATOR PREMIADO À LUZ DO PACOTE ANTICRIME
Authors: Barbosa Bittar Walter , Borri Luiz Antonio , Teixeira Araujo Senedesi João Pedro
Published: June 2022

O presente artigo busca debater o tema do sigilo da colaboração premiada e as consequências derivadas do seu vazamento. Para tanto, examina-se o regime jurídico da publicidade dos atos processuais no ordenamento nacional, com análise específica da colaboração premiada e as modificações da Lei 13.964/19. Por conseguinte, emprega-se o método hipotético-dedutivo formulando-se a hipótese de que a violação do sigilo, por qualquer dos celebrantes do acordo, acarreta a ilicitude probatória. Além disso, para realização da pesquisa utilizou-se da técnica de revisão bibliográfica, com análise de artigos e obras jurídicas que abordam o instituto da colaboração premiada, bem como, a compreensão da jurisprudência dos Tribunais Superiores.
Arbitragem e abuso do processo: análise de comportamentos abusivos na fase pré-arbitral
Authors: Flumignan Silvano
Published: June 2022

O ensaio analisou o comportamento abusivo na fase pré-arbitral. Ele partiu das diferenças entre o abuso de direito e o abuso do processo, buscando verificar a eventual influência de previsões de direito privado para o direito processual civil. Posteriormente, verificou três fases de verificação de comportamento abusivos na arbitragem: pré-arbitral, arbitral e pós-arbitral. Estabeleceu-se como recorte teórico a verificação de comportamentos abusivos na fase pré-arbitral. A última parte prevê as consequências do comportamento abusivo para a fase pré-arbitral. Para o desenvolvimento do trabalho foram utilizados os métodos dogmático e dialético.
DESJUDICIALIZAÇÃO DA EXECUÇÃO, A EXPERIÊNCIA PORTUGUESA E O PROJETO DE LEI N. 6.204/2019: UMA ANÁLISE ECONÔMICA DO DIREITO
Authors: Martins Ronan Medeiros , Godoy Sandro Marcos
Published: June 2022

O artigo estuda o projeto de lei 6.204 de 2019 e suas consequências para os usuários dos serviços judiciais, destacando uma análise acerca do modelo português que serviu de base para o projeto. Conclui-se que a desjudicialização da execução civil nos moldes propostos no projeto de lei não atingirá a eficiência indicada, bem como não haverá a redução de gastos no tanto apresentado, havendo a possibilidade de externalidades negativas aos usuários. O método dedutivo foi utilizado, com apoio da pesquisa descritiva e explicativa, observando-se a utilização de bibliografia e legislação.
TÉCNICA DE AMPLIAÇÃO DO COLEGIADO: BREVE ESTUDO A PARTIR DE REGIMENTOS INTERNOS DE TRIBUNAIS
Authors: De Sousa Ana Luiza Andrade , MARQUES GISELLE PICORELLI YACOUB
Published: June 2022

No presente estudo intentou-se analisar a técnica de ampliação do colegiado, inaugurada pelo Código de Processo Civil de 2015, conforme artigo 942, em substituição ao extinto recurso dos embargos infringentes. O presente trabalho dedicou-se a descrever a previsão de alguns regimentos internos de tribunais de justiça e tribunais regionais federais, com o fito de verificar formas heterogêneas de aplicação da técnica e as consequências para o alcance de sua efetividade.
A PROVA ILÍCITA POR VIOLAÇÃO AO SIGILO PROFISSIONAL DO ADVOGADO
Authors: Oliveira Filipe Ramos
Published: June 2022

O artigo propõe uma análise da ilicitude da prova provocada pela violação ao sigilo profissional do advogado. Elegem-se três situações hipotéticas a fim definir como a garantia do sigilo se articula com a inadmissibilidade das provas ilícitas, estudando-se, ao fim, a forma como o sistema repele essa ilicitude.
PROVAS ILÍCITAS
Authors: Greco Leonardo
Published: June 2022

A reconstituição dos fatos por meio das provas, requisito essencial de efetividade da tutela jurisdicional de direito (inciso XXXV do art. 5º da Constituição Federal), deve ser a mais próxima possível da realidade da vida. No entanto, existem valores constitucionais mais relevantes que impõem limites à busca da verdade, justificando a inadmissibilidade das provas ilícitas (inciso LVI do artigo 5º da Constituição da República). Nesse norte, utilizando-se essencialmente o método de revisão bibliográfica, o objetivo do presente texto é abordar o tema das provas ilícitas, apresentando diretrizes para a admissibilidade ou não da prova à luz da primazia dos direitos fundamentais, por meio de um juízo de ponderação entre a proibição da prova ilícita e a tutela de algum direito fundamental mais relevante do ponto de vista humano  ou interesse público, com a aplicação do princípio da proporcionalidade. Ao final, é apresentado um convite à aplicação das diretrizes sugeridas na resolução de incontáveis situações de aferição da admissibilidade de provas envolvendo colisão de direitos fundamentais, bem como ao aperfeiçoamento do tema pelos estudiosos da ciência processual mediante a rediscussão da sistemática relativa à prova ilícita.
PROCESSOS POR AUDIÊNCIAS NOS CONFLITOS DOS POVOS INDÍGENAS
Authors: Mosmann María Victoria
Published: June 2022

La postergación de las comunidades indígenas en Latinoamérica ha sido materia de reivindicaciones desde la revolución de mayo de 1810 y la situación crítica en la que se encuentran hace que los conflictos que atraviesan la vida de las comunidades indígenas sean múltiples y diversos. De este universo de casos analizaremos en el presente el supuesto de los conflictos que pueden ser sometidos a la justicia ordinaria a través de un proceso por audiencias, intentando indagar sobre la conveniencia o no de su empleo, y en su caso si el proceso por audiencias debe ser adaptado a las especiales circunstancias que reviste un conflicto indígena para cumplir con las garantías que componen la tutela judicial efectiva. La metodología utilizada fue el análisis del marco normativo (normas constitucionales y legales) y jurisprudencial (sentencias de la Corte Interamericana de Derechos Humanos) en materia de protección de los derechos de las comunidades indígenas.Al final, se encontró que el sometimiento de las comunidades indígenas a procesos orales o audiencias in loco (en el territorio de la comunidad) permite brindar una tutela judicial efectiva, al remover los obstáculos económicos y culturales existentes, y adecuar las audiencias a la necesidades indígenas (designación de traductor, intérprete, acompañante, respetando sus costumbres y tradiciones culturales).
PROPORCIONALIDAD PROCESAL Y JUSTICIA CIVIL: TIEMPO DE CAMBIOS
Authors: Campos Santiago Pereira
Published: June 2022

El principio de proporcionalidad procesal ha tenido un amplio desarrollo en Canadá, así como en Reino Unido, Australia y Nueva Zelanda, entro otros países. Sin embargo, no ha sido objeto de mayores estudios o regulaciones en América Latina. Su consagración, desarrollo, adaptación y aplicación en los sistemas latinoamericanos, podrá ser de gran utilidad para fortalecer nuestra Justicia Civil. Analizamos en este trabajo el contexto de en el cual se desarrolla la idea de proporcionalidad, el marco conceptual del principio de proporcionalidad, las aplicaciones prácticas del mismo especialmemente en la experincia canadiense, así como sus fortalezas y debilidades, generando insumos para el análisis de su eventual aplicación adaptada en Latinoamérica. El presente estudio tuvo dos insumos metodológicos fundamentales: por un lado, en análisis in situ en Canadá de la aplicación del principio de proporcionalidad procesal por judicatura y abogacía (mediante entrevistas a juezas, jueces, abogadas y abogados) y, por otro lado, la entrevista a académicos y los estudios doctrinarios sobre el principio de proporcionalidad, tanto en Canadá como en otros países. Se concluye, al final, que la utilización del principio de proporcionalidad requiere diseñar un marco jurídico que siente las bases de la proporcionalidad (bastarían unas pocas normas agregadas a nuestros códigos que ya regulan procesos por audiencias), juezas y jueces comprometidos con un rol de análisis de los casos, abogadas y abogados que tengan incentivos para la actuación proporcional y se adapten a la flexibilidad, capacitación adecuada, recursos mínimamente razonables y la aplicación de metodologías de gestión centradas no solo en la eficiencia (costo-efectividad), sino también en la importancia del caso para el Estado de Derecho y para la sociedad.
O ruralismo na Baixada de Jacarepaguá: a intervenção intelectual na agricultura de subsistência do sertão carioca
Authors: Dória Júlio Cesar De Souza
Published: June 2022

Este artigo se configura como análise do impacto referente às alterações socioeconômicas ocorridas no Brasil na virada do século XIX e início do XX, endossadas pelos governos republicanos no pós-abolição em áreas rurais da cidade do Rio de Janeiro, mas sobretudo, na região de Vargem Grande e, especificamente, na Comunidade de Agricultores Negros e Mestiços que deu origem ao Quilombo Cafundá Astrogilda. Os diversos agentes inseridos neste projeto de transformação da nação atuaram nas franjas da cidade como portadores da nova ordem, capitalista, que alterava os padrões de produção, comercialização e, sobretudo, de vida dos indivíduos que habitavam o sertão carioca. Diante das investidas de outsiders, os camponeses cariocas envidaram esforços e adotaram diversas estratégias de resistência para assegurar os seus direitos básicos de moradia, trabalho e sociabilidade.
Tacrolimus
Authors: Rees Sharon
Published: June 2022

In this column, Sharon Rees aims to refresh knowledge and interest in some of the commonly used drugs in a series of tweets. This month she is talking about #tacrolimus
Climate change and pharmacy
Authors: Winter George
Published: June 2022

George Winter discusses how pharmacy services and climate change action must intrinsically work alongside one another and whether it is possible for one to recognise the importance of the other
Educating non-medical prescribers in the UK – perspectives of programme leads
Authors: Omer Usmaan , Veysey Martin , Crampton Paul , Finn Gabrielle
Published: June 2022

Objectives

Explore the design, delivery and assessment of UK non-medical prescriber (NMP) programmes, and how they prepare prescribers for practice. This was to fill the current gap in knowledge around the specific educational approaches used to train NMPs.

Methods

A qualitative research design was utilised and 16 programme directors from UK NMP programmes were interviewed through the online Zoom app.

Results

These were organised into five major themes: taught content (pertaining to prescribing knowledge, safety, communication and continuing professional development); assessment methods of the programme; aims, objectives and goals of the programme; critical appraisals of programme leads on educational approaches and; improving the programme for future cohorts.

Conclusions

Consideration should be given to adapting the teaching and assessment approaches highlighted by programme leads, particularly towards more interactive, simulated and blended learning approaches.
Surface electromagnetic waves in lossy conductive media: tutorial
Authors: Smolyaninov Igor I.
Published: June 2022

It is commonly believed that electromagnetic waves cannot propagate in lossy conductive media and that they quickly decay inside such media over short length scales of the order of so-called skin depth. In this tutorial, I demonstrate that this common belief is incorrect if the conductive medium exhibits strong gradients of dielectric permittivity. In fact, surface electromagnetic waves in such gradient-permittivity lossy conductive media may have a propagating character, and the propagation length of such waves may be considerably longer than skin depth. Similar to surface plasmons, the wavelength of these waves may be considerably shorter than the light wavelength in free space, which may enable applications in super-resolution microscopy and nanolithography techniques. However, unlike plasmonics-based nanophotonic devices, which are typically built using a very limited number of low-loss optical materials, the newly found class of surface waves may be supported by a much broader range of lossy media. For example, such materials as graphite and silicon seem to be ideal in UV nanophotonics applications.
Single-mode distributed feedback lasing using photonic bandgaps to suppress degenerate modes
Authors: Tennant Bryce A. , Maywar Drew N.
Published: June 2022

We present a method for achieving single-mode distributed feedback lasing, using photonic bandgaps (PBGs) to suppress degenerate lasing modes. These PBGs arise from direct-Bragg coupling and exchange-Bragg coupling due to a passive waveguide placed in proximity to a uniform-grating–active-waveguide lasing structure. Analytic solutions at lasing threshold for this dual-waveguide, four-port structure reveal a high normalized gain margin (e.g., ΔαL = 0.86) accompanied by a low power flatness (e.g., F = 0.001) along the active region, outperforming the λ/4-shifted DFB laser structure. This single-mode lasing mechanism is compelling for both III/V and III/V-on-silicon platforms.
Advancing a hyperlocal approach to community engagement in climate adaptation: Results from a South Florida pilot study in two communities
Authors: Harrison Tyler R. , Clark Angela , Clement Amy , Lombard Joanna , Maranto Gina , Parrish Abraham , Purkis Sam , Reamer Marcus , Collins Olivia , Lewis Caroline , Cruz Mayra , Solache Anaruth
Published: June 2022

With increasing urgency of local and regional climate adaptation, there is a growing need for governments to identify and respond effectively to the concerns of communities they serve and to align investments. We designed and piloted a novel hyperlocal method for urban adaptation planning combining two social science tools that have been widely but separately used to foster community engagement and strategize solutions. Our not-for-profit community partners facilitated multi-session online workshops with participants from two communities in South Florida with whom they have well-established relationships and in which socio-economic conditions and climate risks represent notable vulnerabilities. The workshops first employed photovoice to elicit individual narratives about climate change impacts; participants then followed a design thinking protocol to critically evaluate the leading concerns they identified and propose adaptation solutions. Geospatial mapping and data tools were provided for participants to gain additional tools and further knowledge. Local planning and resilience officials attended some or all of the workshops as observers and interlocutors, dialoguing with participants. Comparative analysis revealed differences in risk awareness and primary concerns between communities, and further demonstrated that concerns and solutions proposed by members of at-risk neighborhoods do not always align with geospatial data that often drives infrastructure adaptation planning in the region, suggesting that more widespread use of community engaged methods could enhance government climate adaptation responses for local communities.
Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model
Authors: Weatherly Sonia M. , Collin Gayle B. , Charette Jeremy R. , Stone Lisa , Damkham Nattaya , Hyde Lillian F. , Peterson James G. , Hicks Wanda , Carter Gregory W. , Naggert Jürgen K. , Krebs Mark P. , Nishina Patsy M.
Published: June 2022

Mutations in the apicobasal polarity geneCRB1lead to diverse retinal diseases, such as Leber congenital amaurosis, cone-rod dystrophy, retinitis pigmentosa (with and without Coats-like vasculopathy), foveal retinoschisis, macular dystrophy, and pigmented paravenous chorioretinal atrophy. Limited correlation between disease phenotypes andCRB1alleles, and evidence that patients sharing the same alleles often present with different disease features, suggest that genetic modifiers contribute to clinical variation. Similarly, the retinal phenotype of mice bearing theCrb1retinal degeneration 8 (rd8) allele varies with genetic background. Here, we initiated a sensitized chemical mutagenesis screen in B6.Cg-Crb1rd8/Pjn, a strain with a mild clinical presentation, to identify genetic modifiers that cause a more severe disease phenotype. Two models from this screen,Tvrm266andTvrm323, exhibited increased retinal dysplasia. Genetic mapping with high-throughput exome and candidate-gene sequencing identified causative mutations inArhgef12andPrkci, respectively. Epistasis analysis of both strains indicated that the increased dysplastic phenotype required homozygosity of theCrb1rd8allele. Retinal dysplastic lesions inTvrm266mice were smaller and caused less photoreceptor degeneration than those inTvrm323mice, which developed an early, large diffuse lesion phenotype. At one month of age, Müller glia and microglia mislocalization at dysplastic lesions in both modifier strains was similar to that in B6.Cg-Crb1rd8/Pjn mice but photoreceptor cell mislocalization was more extensive. External limiting membrane disruption was comparable inTvrm266and B6.Cg-Crb1rd8/Pjn mice but milder inTvrm323mice. Immunohistological analysis of mice at postnatal day 0 indicated a normal distribution of mitotic cells inTvrm266andTvrm323mice, suggesting normal early development. Aberrant electroretinography responses were observed in both models but functional decline was significant only inTvrm323mice. These results identifyArhgef12andPrkcias modifier genes that differentially shapeCrb1-associated retinal disease, which may be relevant to understanding clinical variability and underlying disease mechanisms in humans.
Understanding chaos in COVID-19 and its relationship to stringency index: Applications to large-scale and granular level prediction models
Authors: Necesito Imee V. , Velasco John Mark S. , Jung Jaewon , Bae Young Hye , Lee Jun Hyeong , Kim Soo Jun , Kim Hung Soo
Published: June 2022

Understanding the underlying and unpredictable dynamics of the COVID-19 pandemic is important. We supplemented the findings of Jones and Strigul (2020) and described the chaotic behavior of COVID-19 using state space plots which depicted the changes in asymptotic behavior and trajectory brought about by the increase or decrease in the number of cases which resulted from the easing or tightening of restrictions and other non-pharmaceutical interventions instituted by governments as represented by the country’s stringency index (SI). We used COVID-19 country-wide case count data and analyzed it using convergent cross-mapping (CCM) and found that the SI influence on COVID-19 case counts is high in almost all the countries considered. When we utilized finer granular geographical data (‘barangay’ or village level COVID-19 case counts in the Philippines), the effects of SI were reduced as the population density increased. The authors believe that the knowledge of the chaotic behavior of COVID-19 and the effects of population density as applied to finer granular geographical data has the potential to generate more accurate COVID-19 non-linear prediction models. This could be used at the local government level to guide strategic and highly targeted COVID-19 policies which are favorable to public health systems but with limited impact to the economy.
Condiciones para la apropiación privada legítima de bienes en la teoría de Locke. Efectos de la introducción del dinero sobre ellas y sobre la distribución de la propiedad
Authors: Rodríguez Nasuti Florencia
Published: June 2022

El presente trabajo tiene dos objetivos: por un lado, desarrollar las exigencias derivadas de las condiciones que Locke establece para justificar la propiedad privada de bienes y presentar los efectos que ellas tienen sobre la distribución de la propiedad privada. En especial, me centraré en las dos condiciones que garantizan que dicha apropiación no afecte a la situación de terceros: la condición de la suficiencia, la cual asegura que las personas no pierdan la oportunidad de apropiarse de algún bien, y la condición del no desperdicio, la cual garantiza que los bienes, una vez apropiados, no se echen a perder en manos de sus titulares. Con respecto a la distribución de la propiedad, se mostrará que las condiciones lockeanas evitan que se generen grandes controversias acerca de la distribución existente de recursos, ya que previenen la concentración de su propiedad en pocas manos y aseguran que todas las personas tengan la oportunidad de adquirir algún bien, por lo cual ellas no tendrán motivos para quejarse de las apropiaciones realizadas por otras personas. Por otro lado, mostrar los efectos de la introducción del dinero sobre las condiciones mencionadas y sobre la distribución de la propiedad que de ellas resulta, la cual es ampliamente desigual, explicar la estrategia utilizada por Locke para justificar dicha distribución, vinculada con el consentimiento dado por las personas para la introducción del dinero, y por qué ella puede ser criticada, al resultar afectada la libertad de algunas personas, quienes pierden la oportunidad de apropiarse de algún bien.
Lo súbito como desafío a la imputación penal
Authors: Coloma Correa Rodrigo , Modolell González Juan Luis
Published: June 2022

A partir de un accidente en una competencia ciclística, se realiza un ejercicio de reconstrucción acerca de la posible representación mental y de la voluntad presentes en el participante que lo provocó. El texto propone seis microhistorias de las que se profundiza en las dos más plausibles. Una de ellas pone el foco en las categorías estándar de la teoría del delito (imputación objetiva y subjetiva), y la otra en las particularidades de la reconstrucción psicológicamente más afinada. La primera se reconoce como propia de una perspectiva mecanicista y la segunda, de una contextualista. El mecanicismo constituye una aproximación que al prescindir de ciertos detalles facilita la inserción de nuevos casos dentro de un marco preestablecido y, por tanto representa bien ciertas concepciones de la dogmática penal; el contextualismo, en cambio privilegia construcciones que se hacen cargo de todos los matices y, por tanto, estimula una labor crítica de las categorías asentadas. El análisis es enriquecido con algunos hallazgos recientes en los campos de la psicología y la economía, esto es, las metáforas del pensamiento esforzado v/s automático, junto a las de visión de túnel v/s ancho de banda. Ambas contribuyen a una mejor comprensión del papel de nuestras intenciones en la imputación, por la vía de reconocer relevancia al autocontrol, como al rango temporal a considerar en el análisis. Los problemas detectados invitan a revisar algunos aspectos de las teorías sobre la imputación en el derecho penal.
Análisis del régimen de responsabilidad de los prestadores de servicios para compartir contenidos en línea establecido por el artículo 17 de la Directiva 2019/790
Authors: Suárez Uribe Nicole
Published: June 2022

El sistema de puerto seguro o no responsabilidad establecido en la Directiva 2000/31/CE, aplicado durante veinte años a los prestadores de servicios para compartir contenidos en línea, ha sido objeto de debate por ser un obstáculo a la hora de combatir los ilícitos en materia de Propiedad Intelectual, trayendo como consecuencia jurisprudencia con interpretaciones contrapuestas respecto de las excepciones de responsabilidad para este tipo de intermediarios; de igual modo, surgieron los nuevos servicios de la web 2.0 y cambios en el mercado, factores que culminaron con una propuesta de un nuevo régimen de responsabilidad, el conocido artículo 13, con diversas obligaciones dirigidas en exclusiva a estos prestadores de servicios, lo que significó un cambio de paradigma, objeto de grandes críticas y movimientos que llevaron a múltiples enmiendas hasta su versión final aprobada como artículo 17 en la Directiva 2019/790, la cual se enfrenta a grandes retos para su implementación, de un lado, a nivel legislativo con la transposición por cada Nación y, de otro lado, a nivel práctico para cumplir las disposiciones de manera adecuada, aspectos que abordaremos en detalle en el presente trabajo.
Tecnología y Derecho una mirada al Comercio Electrónico, el Cibercrimen y el Soft Law
Authors: Tapia Sánchez Leónidas Salvador
Published: June 2022

El derecho internacional, el comercio electrónico y la tecnología justifican su relación porque en la Internet o el ciberespacio no existen fronteras terrestres, marítimas o aéreas. Internet, por ende, abarca una pluralidad de jurisdicciones. Dentro del desarrollo de la tecnología, igualmente se habla de nuevos conceptos como personalidad digital, persona digital (usuario), firma electrónica (password), comercio electrónico (e-commerce), ecosistema digital, ciberdelitos y un nuevo término denominado soft law. Hoy, la humanidad se relaciona e interactúa en un planeta virtual o ciberespacio o, mejor dicho, en un ecosistema digital, donde el comercio electrónico es un paradigma a tomar en cuenta. Esto colige que la disrupción digital tiene presencia en todos los continentes y casi todos los países del mundo.
Actualmente, podemos comunicarnos de un continente a otro, de un país a otro con solo tener acceso a Internet y a un dispositivo tecnológico (smartphone, tablet, laptop) y, para ello, no se necesita visa o pasaporte. Sin embargo, dicha cohesión también ha traído concomitantemente la proliferación de ciertas conductas que, a la luz del derecho, no son adecuadas o son ilegales, tal es el caso de los ciberdelitos, los cuales no conocen de fronteras terrestres, marítimas o de cualquier otra índole, ya que se realizan en un entorno digital o virtual. Probablemente, a futuro se crearán fronteras digitales las cuales hoy en día son un noúmeno, con el objetivo de combatir el cibercrimen, lo que generaría también delimitar jurisdicciones digitales y un tribunal ad hoc, instituciones que podrían crearse por medio de un tratado o plantearse desde la academia como forma de coadyuvar a que los Estados logren un consenso, que al final contribuya a combatir los delitos transfronterizos sin afectar el acceso a las tic. El derecho, igualmente, debe evolucionar hacia el ciberderecho o el derecho digital, el cual dentro de sus ramas plantearía el derecho global digital internacional con el objetivo de crear un derecho originario contenido en tratados o convenios internacionales para regular y garantizar la seguridad jurídica, el tráfico de información, la información personal y la justicia en el actual mundo digital.
Por consiguiente, el desarrollo de las Tecnologías de la Información y las Comunicaciones (TIC) es considerado por muchos como la nueva revolución industrial, también denominada Revolución 4.0. Esto ha venido evolucionando desde las últimas décadas del siglo XX y primeros veinte años del siglo XXI provocando un «boom digital» con el desarrollo de los programas informáticos y dispositivos celulares (smartphones), alimentadas por el progreso de la inteligencia artificial.
The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a
Authors: Papaconstantinou John
Published: June 2022

Aging mammalian skeletal muscle satellite cells (MuSCs) undergo a decline of stem cell/progenitor cell proliferative and regenerative capacity, and the development of a physiological milieu characteristic of a state of chronic sterile inflammation. p38αMAPK and ERK1/2 are two major signaling pathways that regulate the age-associated decline of MuSC proliferative capacity. In this review we propose the following mechanism that links the p38αMAPK pathway to the decline of self-renewal and regenerative capacity of aged MuSCs: a) the HS-FGF-2-FGFR1-p38αMAPK-Axis, a tightly linked homeostatic signaling complex, is in synchrony with the autoinhibition of FGFR1; b) autoinhibition contributes to the Axis’ regulation of the homeostasis of P-p38αMAPK activity in juvenile MuSC; c) this combination of protein-protein interactions is characteristic of a juvenile cytoplasmic milieu of beneficial P-p38αMAPK activity and d) includes Sprouty1 inhibition that supports the stimulation of FGF-2 --> miR-29a; e) the miR29a dismantles the basement membrane in preparation for the initiation of replication; f) an age-associated impaired, dysregulated, over-sulfated heparan sulfate ligand (HS)-FGF-2 fails to activate FGFR1 in aged MuSCs; g) this uncouples its regulation of p38αMAPK and ERK1/2 pathways and results in desensitization of FGFR1; h) desensitization of FGFR1 and Sprouty1 interaction in aged MuSC uncouples their regulation of P-p38αMAPK in the aged MuSCs; i) this enables a state of chronic sterile inflammation to promote and sustain an increased level of P-p38αMAPK activity; and, j) the increased activity of P-p38αMAPK in aged MuSC stimulates the production of cell cycle inhibitors, miR-1 and miR-133, thereby attenuating the expression of the cell cycle regulators, SP1 and cyclin D1, resulting in a G1/S arrest; j) the increased level of p38αMAPK activity promotes the apoptosis of the aged activated MuSCs.

This mechanism involves the synergistic interactions of HS-FGF2-FGFR-1, Sprouty (spry1), miR-1, miR-133 and miR-29a that unify the extracellular niche and intracellular milieu for the juvenile vs age-associated regulation of proliferative capacity of the MuSC. Our hypothesis unifies these interactions with the role of the extracellular niche and intracellular milieu in the stimulation of juvenile proliferation vs age-associated decline of skeletal muscle satellite cell self-renewal and regenerative proliferation. Word Count = 344
Evaluation of Bioactive Compounds and Mineral Composition in Thai-Variety Amaranths
Authors: Chunthawodtiporn Jareerat , Manochai Benya , Santhi Kornkanok , Pornwongthong Peerapong
Published: June 2022

Amaranth is one of the high nutrient vegetables with high proteins, vitamins, and mineral contents. However, the accumulated pigments and nutrients may change by plant growth stages. Therefore, this study explored the phytonutrients and mineral composition in three amaranth varieties with five harvesting stages. The results revealed that plant pigments were highest accumulated at the reproductive stage with anthocyanin and β-carotene contents of 0.82 and 141.21 mg/g fresh weight (FW), respectively. Contrastingly, vitamin C contents were highest at the marketing stage (1,904 mg/g FW). Accumulations of Ca and K increased over cultivation time, whereas Zn contents were higher at the younger stages. However, Fe contents were not different by growth stages or varieties. From all measurements, only β-carotene and vitamin C accumulations were different among plant varieties. Compared to the WHO food recommendations, amaranths are excellent sources of β-carotene, antioxidants, calcium, potassium, and iron. Additionally, the associations among traits were evaluated and found that most traits were positively correlated with the growth stage, whereas zinc contents were strongly negatively correlated. These results provide a clear picture of amaranth’s nutrition for consumers and suggest the appropriate harvesting time for specific nutritional benefits as well as promoting the consumption of these vegetables.
ANALISIS KOMPARATIF PEMIKIRAN FILSAFAT POLITIK AL-FARABI DAN PLATON
Authors: Mahendra Richo Bintang
Published: June 2022

This article describes about the original dimensions of al-Farabi's Islamic political philosophy by comparing it with Plato's political philosophy. The originality of philosophical thought in Islam was questioned critically by the orientalists. Orientalists had claimed that Islamic philosophy is simply a diversion from Greek philosophy. However, Islamic philosophy is an elaboration of classical Greek philosophical thought. In the hands of Muslim philosophers, Greek philosophical thought reached perfection. So that it cannot be said that Islamic philosophical thought is only diversion of Greek philosophy. This elaboration effort appears in the thought of Al-Farabi's political philosophy which is considered very Platonnic. In this case, there are fundamental differences between Platon's political philosophical thought and the political philosophy thought was built by Al-Farabi. The difference lies in their analysis of the ideal leader, the goals of the state, and the classification efforts of good and bad governance political regimes. Through these differences, it can be seen that Al-Farabi's political philosophy has its own characteristics, that is a combination of faith and philosophy.
ETIKA ANAK BANGSA PERSPEKTIF PANCASILA
Authors: Solissa Abdul Basir
Published: June 2022

Pancasila as the basis of the State, the state ideology, and the nation's view of life are national agreement and national compromise of various interest groups. Pancasila was agreed as a final meeting point, therefore Pancasilamust be the starting pointin overcoming all problems of national and state life.One of the complicated problems that are currently happening is Indonesian community behavior that is already not in line with the Pancasila values.In this context Pancasila must be placed not only as the basis of the State, the state ideology, and the nation's view of life, but also must be the basis of ethics, the value standard, and the moral standards. This article examines the three main areas that become the pulse of the life of the nation, that is politics, economics and social media.The behavior of the Indonesian community in the three main streams, read from the Pancasila perspective, therefore expected to give birth to a new awareness in the rule of a nation which is more balanced, humane and enlightening.
PARIPATETIC TRADITION AND METAPHYSICS IN AL-FARABI’S PHILOSOPHY: THE WAY OF HAPINESS
Authors: Rachman Aulia
Published: June 2022

AbstractThis article discusses about metaphysics in al Farabi's peripatetic philosophy, particularly about happiness. In the historical study of philosophy, this belief was grounded through the peripatetic method. In this peripatetic tradition, there are several central themes that become profound discourses in philosophical discourse, including metaphysical concepts. The metaphysical concept has a unique distinction in its position in Islamic philosophy. One of them is from Al-Farabi's view, which views that mastery of metaphysical concepts has an important role in creating happiness. For this reason, this paper will discuss what is the peripatetic tradition in history, metaphysical concepts that exist in the realms of Islamic philosophy and discuss the relationship between metaphysical concepts and the concept of happiness owned by Islamic philosophers, namely Abu Nasir Muhammad bin al-Farakh Al-Farabi (872-951).
ISLAM DAN SAINS: ANTARA ISLAMISASI ILMU, PENGILMUAN ISLAM, DAN TRANSINTEGRASI ILMU
Authors: Saripuddin Saripuddin , Syukri Ahmad , Badarussyamsi Badarussyamsi
Published: June 2022

This article discusses a comparative study between the Islamization of knowledge, Islamic science, and the transintegrasi of sciences. What are the similarities and differences between the three? Why do the three of them have different views about the form of the encounter between science and Islam? To answer this question, this article uses an epistemological and historical approach. This article finds that there are two similarities between the three, namely they an Islamic response to the development of science and they reject secularism. Meanwhile, the difference between the three lies in the emphasis and the details of the key concepts. The difference between the three occurs because of the different epistemological and historical backgrounds between the three.
Prospective Investors Perception on Investment Intention in Indonesia Sharia Stocks Market: A Conceptual Framework
Authors: Putri Dika Riri
Published: June 2022

Capital markets are an important component of the financial system, investment decisions are important for one’s future and these decisions are related to many factors. Investment is one of the teachings and concepts of Islam and the emergence of sharia stocks in the Indonesian capital market opens up opportunities for the Indonesian Muslim community to invest. As a country with the largest Muslim population globally, Indonesia is a country with the largest sharia capital market share globally. This should encourage and facilitate Islamic investors to invest in the Indonesian economy, especially the capital market. Yet the fact is, sharia stocks are still lower than the growth target The number of studies on the intention to invest in stocks in Indonesia which is relatively few led this study to try to test the influence of behavior on attitudes, subjective norms and behavioral control perceptions on the intention to invest in stocks. This research paper aims to study the perception of prospective investors on factors that will influence their investment intention in sharia stocks in the Indonesian Stock Exchange. This study uses the theory of planned behavior (TPB) with attitudes, subjective norms and behavioral control as independent variables. This study combines three critical things namely, attitudes, subjective norms and behavioral control of assumptions. This research adopted a quantitative method using questionnaire distribution and analyses using SEM-PLS. The results of the research will contribute to the field of management and consumer behavior in decision making to investment. From this research, Indonesians can know and invest in the Indonesian stock market, especially sharia stocks. Research also contributes to the development of knowledge in the field of finance that focuses on investor behavior.

Keywords: Attitude, Subjective Norms, Behavior Control, Intention, Sharia Stocks, TPB
Layla s Fire
Authors: Al-Rifai Nada Yousuf
Published: June 2022

The poem is a kind of religious courtship, woven according to Sufi patterns of poetry and divine love. The poem deals with the journey of the poet to search for spiritual tranquillity and the absolute reality for which he puzzledly travelled out at night so that he might be guided to its holy fire with his companions.

He starts his poem by describing the hardships of travelling at night to search for his aimed and beloved Laila and the plight of access to the homes of her people on a high plateau. Their fire was glowing from the distance, which indicates their prestige and the elevation of their place. He then describes the difficulties he suffered on his way until he discarded his travelling stick and met the beloved. In his first verses, the poet pictured his situation among a group of people who did not fall under the influence of the factors that made him a unique man in their convoy. They blamed him and mocked him and thought that he was deceived by false lightning. Love or ambition is the motive for embarking on this journey despite the difficulties that weigh the fates of those who walk in various scales because they have different conditions and natures in their positions on the path to the Divine Being. Each has a beginning and a door through which he enters. There are fluctuations, trainings, adversity, horrors, and valleys of fall.
Use of Arbitration in the Settlement of Intellectual Property Disputes in Nigeria
Authors: Nwogu Mary Imelda Obianuju
Published: June 2022

Intellectual Property (IP) protects exclusive ownership, use and/or exploitation of IP rights. The infringement of the said rights give rise to disputes which can be settled by Arbitration. Arbitration is an Alternative Dispute Resolution (ADR) Mechanism, which can be used in the settlement of Intellectual Property (IP) disputes by the agreement of the parties. This method of settling IP disputes is cheaper, faster, more confidential and encourages party autonomy than litigation. Pima facie, IP disputes are arbitrable, though in Nigeria there is no specific law on arbitrability of IP disputes, but there are instances or provisions within the Trademarks Act and Federal High Court Act which permit the deployment of Arbitration to such disputes. WIPO Arbitration and Mediation Centre has settled several mediation and arbitration disputes. The confidential nature of arbitral proceeding has made it particularly advantageous for settling IP cases owing to the delicate nature of the information and documents involved.
The Effect of Internal Meaning on Purchase Decision With Attitude Mediation: A Quantitative Explanatory Study of Brawijaya University Students' Internal Meaning of BTS Meal Co-Branding Products
Authors: Pranata Riky
Published: June 2022

This research is a study of the study of internal meaning in the study of marketing communications, based on Osgood's theory or commonly known as the semantic meaning theory. in Osgood's theory, the meaning of a person is said to lie in a metamorphosis space which consists of three main dimensions, namely evaluate, activity, and potency. The purpose of this study was to analyze the effect of internal meaning on purchase decisions with Attitude mediation. The research object chosen was the BTS Meal co-branding product, which was the result of a collaboration between McDonald’s and the K-Pop boy band Bangtan Boys (BTS). The research sample used a convenience sampling technique consisting of 100 Brawijaya University students from various faculties. This type of research is quantitative and the method used in this research is a survey. The data analysis method used in this study is Partial Least Square (PLS) with the help of the SmartPLS Version 3 program.

The findings of this study revealed that the influence of internal meaning on purchase decision with evaluate indicator through Attitude mediation does not affect purchase decision. The influence of internal meaning on purchase decision with activity indicator through mediation Attitude affects purchase decision. The influence of internal meaning on purchase decision with potency indicator through mediation Attitude affects purchase decision. The results of this study reveal that Attitude affects purchase decision.
Rousseau i Tocqueville: przeciwstawne wizje republikańskiego wychowania
Authors: Mirocha Łukasz
Published: June 2022

It is legitimate to speak about two philosophies of education as presented by Jean-Jacques Rousseau. The first of the philosophies was elucidated in Emil, or on Education and its aim was to provide principles governing the process of upbringing of the man. Philo-sophical grounds for the second one were comprised in The Social Contract, however description of the education itself is delivered by Considerations on the Government of Poland. This concept refers to the civic education, education of the political community mem-ber. Alexis de Tocqueville depicts vision of education that varies fundamentally from the both grounded in Rousseau’s writing. Toc-queville’s vision stays at odds with the philosophy given in Emil, because it concerns civic aspects of the education. It is also not com-pliant with the concept stemming from Considerations, due to the fact that it stresses the role of other than state subjects in the edu-cation. The article comments on all three concepts of education out-lined above and finally relates them to the concept of positive and negative liberty provided by Isaiah Berlin.
Some remarks on applications of analogy within intercultural dialogue
Authors: Dudek Agnieszka Helena
Published: June 2022

In this article I present some applications of analogy with reference to intercultural dialogue, firstly as a process in which the familiar structure of a direct experience in one situation improves awareness of an expected experience within another structure. Secondly, I follow the Enrique Dussel’s approach according to which where analogy is the key element of a true dialogue. In the paper conceptions of Ryszard Kapuściński, Martin Buber, Józef Tischner are presented in the context of intercultural dialogue and are applied to Yuko Abe’s analysis of students exchange experiences.
De minimis aid in agriculture and its registration in Spain. The new legislative project for the organisation of agricultural information
Authors: Muñiz Espada Esther
Published: June 2022

This article analyses the register and rules on the basis of which de minimis aid is granted in Spain. The characteristics and main types of agricultural activities that are subject to registration are characterised. The undertaking of this study was prompted by the peculiarity of administrative registers in Spain, which, by virtue of defining the rules of agricultural activity, belong to agricultural law, while these rules call for an urgent reform in order to increase their efficiency.