bluuebunny/crossref_metadata_2025 huggingface dataset:
CONSTRUCTION OF STABILITY DOMAINS FOR LINEAR DIFFERENTIAL EQUATIONS WITH SEVERAL DELAYS
Authors: Klevchuk I. , Hrytchuk M.
Published: November 2022

The aim of the present article is to investigate of solutions stability of linear autonomous differential equations with retarded argument. The investigation of stability can be reduced to the root location problem for the characteristic equation. For the linear differential equation with several delays it is obtained the necessary and sufficient conditions, for all the roots of the characteristic equation equation to have negative real part (and hence the zero solution to be asymptotically stable). For the scalar delay differential equation $$ \frac{dz}{dt}=c z(t) + a_1 z(t-1) + a_2 z(t-2) + ... + a_n z(t-n), $$ with fixed $c$, $c \in \mathbb{R}$, $a_k \in \mathbb{R}$, $1 \leq k \leq n$, stability domains in the parameter plane are obtained. We investigate the boundedness conditions and construct a domain of stability for linear autonomous differential equation with several delays. We use D-partition method, argument principle and numerical methods to construct of stability domains.
APPROXIMATION OF BOUNDARY VALUE PROBLEMS FOR INTEGRO-DIFFERENTIAL EQUATIONS WITH DELAY
Authors: Tuzyk I. , Cherevko I.
Published: November 2022

In mathematical modeling of physical and technical processes, the evolution of which depends on prehistory, we arrive at diﬀerential equations with a delay. With the help of such equations it was possible to identify and describe new eﬀects and phenomena in physics, biology, technology. An important task for diﬀerential-functional equations is to construct and substantiate ﬁnding approximate solutions, since there are currently no universal methods for ﬁnding their precise solutions. Of particular interest are studies that allow the use of methods of the theory of ordinary diﬀerential equations for the analysis of delay diﬀerential equations. Schemes for approximating diﬀerential-diﬀerence equations by special schemes of ordinary diﬀerential equations are proposed in the works N. N. Krasovsky, A. Halanay, I. M. Cherevko, L. A. Piddubna, O. V. Matwiy in various functional spaces. The purpose of this paper is to apply approximation schemes of diﬀerential-diﬀerence equations to approximation of solutions of boundary-value problems for integro-diﬀerential equations with a delay. The paper presents suﬃcient conditions for the existence of a solution of the boundary value problem for integro-diﬀerential equations with many delays. The scheme of its approximation by a sequence of boundary value problems for ordinary integro-diﬀerential equations is proposed and the conditions of its convergence are investigated. A model example is considered to demonstrate the given approximation scheme.
Resistance Design vs War Design
Authors: Vezhbovska Liliana
Published: November 2022

Today design is becoming a tool of war. Projecting a small section of life or information space, a designer himself is not actually fully realizing that he makes a global impact. He spreads the form, in which human consciousness consumes both industrial and informational product. The armed war launched by the Russian Federation against Ukraine has not yet begun and was prepared in a way that does not directly bring death and destruction. It was prepared by creating a "parallel reality" primarily in people’ consciousness through achievements in the field of design with a combination of high technologies including web design, virtual and augmented reality, collage and photomontage. Even those elementary visual formulas that were given by the Bauhaus or the avant-garde, minimalism and deconstructivism were used with the opposite effect and primarily for the manipulation of human consciousness.
FRAMEWORK PEMBELAJARAN MATEMATIKA REALISTIK BERBASIS FLIPPED CLASSROOM TERHADAP MINAT BELAJAR SISWA SEKOLAH DASAR DI MASA PASCA PANDEMI
Authors: Agustin Yolanda Indra , Rindaningsih Ida
Published: November 2022

Penelitian ini di latar belakangi oleh rendahnya minat belajar siswa pada mata pelajaran matematika di masa pasca pandemic. Minat belajar merupakan salah satu faktor penting dalam pembelajaran. Oleh karena itu dalam upaya meningkatkan minat belajar siswa sekolah dasar  (SD) pada mata pelajaran matematika maka berbagai pendekatan pembelajaran senantiasa dikembangkan, salah satunya adalah pembelajaran matematika realistik. Meski demikian, masih banyak dijumpai rendahnya minat belajar siswa sehingga perlu adanya model pembelajaran yang tepat yakni flipped classroom. Tujuan dari penelitian ini adalah untuk menganalisis pengaruh framework matematika realistik berbasis flipped classroom terhadap minat belajar peserta didik. Penelitian ini termasuk penelitian quasi eksperimen dengan menggunakan design Randomized Post-test Only Control Design. Populasi dalam penelitian adalah siswa kelas V MI Nurul Huda Candi Sidoarjo yang terdiri dari dua sampel penelitian sebanyak 20 siswa kelas eksperimen dan 20 siswa kelas kontrol. Teknik analisis data yang di gunakan adalah uji independent sample t-test. Berdasarkan analisis uji perbedaan rata-tata hasil tes minat belajar siswa di peroleh nilai Signifikansi yaitu 0,000 < daripada 0,05. Yang artinya H0 di tolak dan Ha diterima. Oleh karena itu temuan dalam penelitian ini adalah terdapat  pengaruh framework pembelajaran matematika realistik berbasis flipped classroom yang dapat meningkatkan minat belajar siswa.
PENGEMBANGAN MEDIA BERBASIS ANDROID PADA MATERI SISTEM TATA SURYA UNTUK MENINGKATKAN PENGUASAAN KONSEP SISWA
Authors: Siti Deti Nurhamidah  , Atep Sujana  , Dety Amelia Karlina
Published: November 2022

Pada masa kini pembelajaran lebih menekankan terhadap penggunaan teknologi sebagaimana ciri pembelajaran abad 21. Pengembangan media berbasis android dirasa penting untuk memenuhi kebutuhan pembelajaran karena penggunaannya di sekolah dasar masih sangat minim. Penelitian ini bertujuan untuk menguji kelayakan aplikasi yang dihasilkan sebagai media pembelajaran di sekolah dasar dan mengetahui keefektifannya dalam meningkatkan pemahaman konsep siswa. Penelitian menggunakan metode R&D (Research and Development) dengan model ADDIE (Analyze, Design, Development, Implementation, Evaluation). Penelitian dilakukan di salah satu sekolah dasar Kecamatan Lemahsugih Kabupaten Majalengka, Jawa Barat dengan subjek penelitian berupa validator ahli materi dan ahli media, guru serta 10 siswa kelas VI. Teknik pengumpulan data menggunakan observasi, angket dan tes. Instrumen yang digunakan berupa angket yang diberikan kepada ahli materi, ahli media dan guru selaku praktisi pembelajaran IPA di SD dan soal tes diberikan kepada 10 siswa kelas VI. Analisis data dilakukan secara deskriptif kuantitatif. Aplikasi yang dihasilkan sangat valid dengan perolehan presentase aspek materi 88% dan aspek media 95,4%. Hasil uji kelayakan aplikasi memperoleh nilai presentase 95% dalam kategori sangat layak. Selanjutnya hasil tes berupa pretest dan posttest dengan one group pretest-posttest design terhadap 10 orang siswa kelas VI didapatkan hasil pretest rata-rata 56,00 dan posttest rata-rata 80,00 sehingga disimpulkan hasil posttest > pretest, artinya hasil belajar siswa mengalami peningkatan. Berdasarkan temuan penelitian tersebut, dapat dinyatakan bahwa media pembelajaran berbasis android berupa aplikasi sistem tata surya dapat meningkatkan penguasaan konsep siswa sehingga layak untuk digunakan sebagai media pembelajaran di sekolah dasar.
Polemik Tradisi Menabuh Golomang dalam Ritual Pemakaman Pada Masyarakat Muslim Bolaang Mongondow
Authors: Tungkagi Donald Qomaidiasyah , Mokodongan Tasya Aziza
Published: November 2022

Penelitian ini membahas tradisi menabuh golomang dalam ritual pemakaman masyarakat muslim di Bolaang Mongondow, Sulawesi Utara. Penelitian ini menggunakan metode deskriptif kualitatif. Temuan penelitian ini menunjukkan adanya polemik terhadap keberadaan musik tradisional golomang dalam ritual pemakaman masyarakat muslim Bolaang Mongondow. Terdapat tiga faktor yang mendasari munculnya polemik dalam masyarakat: pertama, masih kuatnya persepsi masyarakat yang memandang penggunaan musik golomang hanya dapat dilaksanakan oleh keturunan bangsawan; kedua, terjadi kontestasi tradisi di dalam masyarakat yang memandang penggunaan musik dalam ritual pemakaman tidak selaras dengan ajaran Islam; ketiga, terdapat pandangan masyarakat yang menganggap alat musik umumnya digunakan sebagai media hiburan dan senangsenang semata, sehingga penggunaan musik golomang dalam ritual pemakaman dianggap tidak menghormati pihak yang berduka. Meskipun keberadaan musik dalam ritual pemakaman masih terjadi pro dan kontra, namun fakta menunjukkan tradisi ini terus-menerus bertumbuh, bahkan mengalami proses adaptasi dan pencarian makna baru. Pementasan musik golomang tidak lagi sebatas dalam ritual pemakaman, namun dipentaskan juga dan perkawinan, dan kesenian pertunjukkan khalayak.
Dimensi Permainan Maddende dalam Meningkatkan Kecerdasan Interpersonal Anak
Authors: Halifah Syarifah , Mustamin Fitriani , Razak Rasmida
Published: November 2022

Artikel ini membahas permainan Maddende yang dilakukan oleh anak-anak pada sekolah TK Al-Imaniah di Kota Parepare. Dimensi ruang anak usia dini adalah bermain, namun pada kenyataannya ruang bermain anak yang disediakan oleh sekolah PAUD belum mengakomodasi sesuai perkembangan anak pada usia 5-6 tahun. Pada sisi yang sama, mood anak-anak dalam bermain mengalami ritme yang tidak konstan sehingga memunculkan prososial negatif seperti hiperaktif dan tantrum. Objek penelitian ini adalah anak didik pada kelompok B di TK Al-Imaniah. Data dikumpulkan melalui observasi dan melakukan wawancara serta memanfaatkan dokumen-dokumen perangkat pembelajaran dan aktivitas anak-anak. Penelitian ini bertujuan untuk mendeskripsikan dimensi permainan maddende yang dipraktikkan TK AlImaniah dalam upaya meningkatkan kecerdasan interpersonal anak usia dini. Temuan penelitian ini menunjukkan bahwa permainan maddende mengandung dimensi untuk meningkatkan kecerdasan interpersonal anak sehingga mereka mampu beradaptasi, bekerjasama, serta dapat memahami situasi lingkungannya.
Prosesi Mappasiarekeng dalam Tradisi Perkawinan Masyarakat Bugis di Ajangale
Authors: Usman Usman , Kaharuddin Kaharuddin
Published: November 2022

Artikel ini membahas prosesi mappasiarekeng yang khas dalam tradisi perkawinan masyarakat Bugis di Ajangale. Kajian ini bersifat kualitatif yang dipaparkan secara deskriptif analitis. Teknik pengumpulan data diawali dengan observasi, kemudian dilakukan pengamatan dan wawancara langsung kepada informan. Penelitian ini dilakukan bertujuan untuk mengetahui fungsi prosesi mappasiarekeng dalam tradisi perkawinan masyarakat Bugis yang khas dilakukan di wilayah Ajangale Kabupaten Bone. Prosedur analisis dilakukan yakni diawali dengan memaping data, kemudian menafsirkan, dan menyajikannya hingga mencapai kesimpulan. Hasil penelitian yang dicapai menunjukkan bahwa, prosesi mappasiarekeng merupakan bahagian penting yang dilaksanakan oleh masyarakat Bugis di Kecamatan Ajangale yang keberadaannya masih bertahan hingga dewasa kini. Prosesi mappasiarekeng merupakan sebagai bahagian dari tradisi perkawinan, yang dasarnya tidak diatur secara formal dalam syariat Islam. Namun, dalam tradisi suku Bugis di Ajangale kegiatan ini menjadi tahapan yang wajib dilaksanakan menurut adat-istiadat masyarakat. Adapun fungsi mappasiarekeng bagi masyarakat Bugis di Ajangale yaitu memosisikannya sebagai tahap penguatan atas kesepakatan hal-hal yang telah diputuskan pada mappettuada (lamaran) yang telah dilakukan sebelumnya, mencakup: tanra esso (penentuan hari akad), dui menre’/dui balanca (uang belanja), sompa (mahar), dan hal-hal lainnya. Fungsi lain mappasiarekeng yaitu tercapainya mufakat, menciptakan suasana kekeluargaan, serta menciptakan rasa kebersamaan antara keluarga kedua belah pihak.
MODERN CEZAYİR TİYATROSU'NA BİR BAKIŞ
Authors: GÖKGÖZ Turgay
Published: November 2022

132 yıl boyunca Fransız işgalinde kalan Cezayir’de halk ve doğal olarak edebiyat, baskı ve sansür altındaydı. Fransızlar okuyan, eğitimli ve bilinçli bir nesilden ziyade kendisine hizmet eden bir toplum oluşturma gayesindeydi. Bu nedenle Cezayir’de gerçekleştirilen uygulamalar halkı cahilleştirme ve İslam’dan uzaklaştırma politikası çerçevesinde belirlenmiştir. Bu bağlamda özellikle 1930’lu yıllarda gençlerin bilinçlenmesi ve eğitim almaları adına insanlar evlatlarını Tunus’a Zeytûne Üniversitesi’ne göndermiştir. Zamanla Cezayir’de devrim hareketi başlamış ve 1962 yılında ülke, Fransızlardan bağımsızlığını ağır bedeller ödeyerek kazanmıştır. Bu nedenle ülkede edebiyat özellikle de Doğu Arap ülkelerinin gerisinde kalmış, öykü ve roman gibi tiyatro da geç ortaya çıkan bir sanat olmuştur. Fransızlar döneminde tiyatronun varlığı bilinse de Cezayir insanı bu sanattan mahrum bırakılmış ve daha çok Fransızlar tiyatro sanatı ile ilgilenmişlerdir. Cezayir’de tiyatro sanatının halka ulaşabilmesi adına rastlanan ilk örneklere bakıldığında, bu örnekler daha çok çeviriler ve uyarlamalardan oluşmaktaydı. 1920’den itibaren oluşturulan tiyatro toplulukları, ülkeye Doğu Arap ülkelerinden gelen tiyatro topluluklarından ilham almışlardır. Bağımsızlığa kadar Cezayir’de pek çok tiyatro topluluğu sayesinde nice oyun sahnelenmiştir. Bağımsızlık sonrasında Cezayir tiyatrosu gelişme kaydetmiş ancak 1990’lı yıllarda yaşanılan iç savaş nedeniyle sekteye uğramıştır. Buna rağmen tiyatro ayakta kalabilmiş, özgün eserler verebilen oyuncularını ve yazarlarını yetiştirebilmiştir. Bu çalışmada doğuşundan günümüze değin Cezayir Tiyatrosu’nun gelişim seyri hakkında detaylı bir şekilde bilgi vermek amaçlanmıştır
Synthesis and antidepressant-like activities of some piperidine derivatives:
involvements of monoaminergic and opiodergic systems
Authors: Kaya Ceren , Turan Yücel Nazlı , Kandemir Ümmühan , Osmaniye Derya , Can Özgür , Demir Özkay Ümide
Published: November 2022

It was aimed to synthesize some novel piperidine derivatives and investigate their antidepressant-like activities, in this study. Targeted compounds were obtained by reacting 1-(4-(substitutedpiperidin-1-yl)phenyl)ethan-1-one and heterocyclic aldehydes in methanol. The structures of the synthesized compounds were determined using data from various spectroscopic methods (IR, 1H-NMR, 13C-NMR, and LCMSMS). The compounds (50 mg/kg) were tested for their antidepressant-like effects by tail suspension and modified forced swimming tests (MFST). In addition, possible alterations in locomotor activities of mice were evaluated by activity cage measurements. Obtained results showed that compounds 2c-2f reduced the immobility time of mice in both of the antidepressant activity-screening tests indicating that these derivatives have antidepressant-like effects. Moreover, in MFST, compounds 2c and 2e significantly increased the swimming times, while compounds 2d and 2f significantly prolonged the climbing durations. Antidepressant-like effects of the compounds 2c and 2e was reversed with p-chlorophenylalanine methyl ester (serotonin depleting agent) pre-treatments while the same effect caused by the compounds 2d and 2f was abolished by pretreatment with α-methyl-para-tyrosine methyl ester (catecholamine depleting agent) pre-administrations. Moreover, pre-treatment with naloxone reversed the antidepressant-like effects of these four derivatives. Obtained results indicated that monoaminergic and opioidergic systems mediated the antidepressant-like effects of our novel piperidine derivatives.
An insight of FDA-approved drugs for the management of aging related disorder a in silico study
Authors: Yang Tong-jie , Wan Quan-qing , WEN PENG-PENG
Published: November 2022

Skeletal muscle (SM) is a most complex and plastic tissues of the human body. Movement, postural support, breathing, and thermogenesis are important functions of SM. Muscle mass reduction is a common side effect of human aging. The growth factor myostatin (MSTN) appears to play a key role in aging-related muscle function decreases. Targeting MSTN might help people live longer by preventing SM alterations associated with aging. Therefore, in the present study, FDA-approved drugs (from 2015 to 2020, total 273 drugs) were screened against MSTN to find the best drugs against MSTN for the management of aging disease. In this regards, Screening, docking, and molecular dynamics simulation was used. Based on structure-based virtual screening and free energy of bind, we select the top five drugs as mentioned in this article. Two drugs were analyzed in-depth namely, Sonidegib and Revefenacin showing free energy of binding -10.95 and -12.03 kcal/mol respectively with MSTN. Further, these complex was forwarded for molecular dynamics simulation to check the structural stability during 100ns, which was found to be more stable. As a concluding remark, Sonidegib and Revefenacin can be considered for further designing of new drugs against MSTN for the treatment aging related disorders.
Improved medication adherence with smart applications and medication dispensers - a literature review
Authors: Keidong Hanna , Volmer Daisy
Published: November 2022

Introduction: Medication adherence has a crucial part in ensuring treatment effectiveness. With polypharmacy, medication regimen may be complicated to follow. Smart devices and applications may be useful for geriatric patients, especially in case of cognitive dysfunction.
The aim of this narrative literature review is to briefly evaluate the main principles of the use of medication dispensers and smart applications to support medication adherence.
Methods: Literature review of peer-reviewed studies in adults (i.e. 18 years or older) and of the period 2012-2021 were selected to collect information about smart medication dispensers and smart applications to monitor medication adherence. The PubMed and Scopus databases were used for review.
Results: Digital solutions were found useful for elderly patients, who have multiple medications in their treatment schemes. Younger patients could benefit more from mobile apps, as these tend to be easy to use and operate.
Conclusions: Different digital solutions can successfully be used in different age groups to enhance medication adherence. Target group must be set beforehand the development. Further improvements are needed to use the full potential of data produced by devices for monitoring and supporting patients´ medication use.
Platelet-rich plasma counteracts interleukin-1 induced inhibition of collagen biosynthesis through recovery of impaired β1-integrin signaling and prolidase activity in human skin fibroblasts.
Authors: Guszczyn Tomasz , Chalecka Magda , Kazberuk Adam , Ościłowska Ilona , Pałka Jerzy , Surażyński Arkadiusz
Published: November 2022

Although inflammation is the first step in wound healing, it contributes to down-regulation of collagen biosynthesis delaying the process of tissue regeneration. The study was conducted to evaluate the effects of platelet-rich plasma (PRP) on interleukin-1β (IL-1β) – dependent inhibition of collagen synthesis, prolidase activity, and β1-integrin signaling in cultured human skin fibroblasts. PRP was obtain using the SmartPReP®2 Autologous Platelet Concentrate+ System. Collagen biosynthesis and prolidase activity were measured in confluent human skin fibroblast cultures with IL-1β, PRP, hyaluronic acid (HA), and mixtures of IL-1β with PRP or HA. Immunofluorescence bioimaging analysis was employed to evaluate expression of β1 integrin receptor, cyclooxygenase-2 (COX-2) and nuclear factor-κB (NF-κB) protein. Incubation of fibroblasts with 2% PRP for 24 h contributed to about 500% increase in collagen biosynthesis and a significant increase in the expression of β1-integrin receptor and prolidase activity, compared to the control cells. In the cells treated with IL-1β, collagen biosynthesis, β1-integrin receptor expression, and prolidase activity were decreased while COX-2 and NF-κB expressions were significantly increased. All these processes were recovered to control values by PRP or HA; however, PRP was found to act more effectively than HA. It was found that PRP counteracted IL-1β -dependent inhibition of collagen synthesis through recovery of β1-integrin receptor expression and prolidase activity and down-regulation of COX-2 and NF-κB expressions in cultured fibroblasts. The data suggest that PRP evoke anti-inflammatory activity that is desirable in tissue regeneration.
Desain Kurikulum SMK Negeri 8 Malang sebagai Lembaga Pembelajaran Karakter Disiplin Budaya Kerja (Studi Fenomenologi)
Authors: Afifin M. Odik
Published: November 2022

The increase in the unemployment rate by 9.27% was due to the workforce from vocational school graduates who had not been able to be absorbed optimally by the world of work. However, many graduates of SMK Negeri 8 Malang have the opportunity to immediately get a job after graduating in several leading DU/DI in Indonesia. The purpose of this study was to determine the curriculum design of SMK Negeri 8 Malang as a discipline character learning as a work culture institution with indicators of students' ability to be able to adapt and get used to completing work in the industrial world. This study was designed using a qualitative method and a phenomenological approach, namely research based on observations of subjective experience or phenomenological experience. The results showed that students were accustomed to completing assignments correctly and often some of them were able to complete theoretical and practical assignments before the deadline for submission. The integrated learning system of habituation of disciplined characters at SMK Negeri 8 Malang is very helpful for students in getting used to the world of work.
DAMPAK POSITIF DISCOVERY LEARNING MODELS TERHADAP PENINGKATAN KEMAMPUAN DASAR BERHITUNG SISWA
Authors: Supriyanto Agus , Budiman Khamid , Martaningsih Sri Tutur
Published: November 2022

Primary school students' numeracy skills require learning stages following student development. Ignorance of the formula with mastery of calculating material is an obstacle, especially in the Covid-19 pandemic conditions. Model discovery learning can apply to online learning conditions. The research goal is to improve numeracy skills through discovery learning models (MDL). We applied classroom action research with study subject grade IV students. MLD with the numeracy skill discuss in this research. The application of the research was two cycles. This study's data collection methods were observation and tests in observation sheets and test questions. Data analysis using descriptive qualitative and descriptive quantitative. The findings showed that the use of MLD could improve the numeracy skills of students of primary school. The development of the first cycle is the value of MDL implementation of 87% with the rata-rata value of the numeracy ability of students of 94 and the acquisition of the result of the second cycle is the value of the implementation of the MLD of 95% with the rata-rata of the numeracy ability of the students of 97. Increasing numeracy skills with the application of MLD can be applied to primary school students. The role of guidance and counselling teachers with primary school teachers in collaboration develops students' numeracy skills in the digital era.
An Analysis of Risk Factors Affecting Suicidal Ideation among Higher Education in Malaysia using Analytic Hierarchy Process
Authors: Chan Sin Yin , Ch'ng Chee Keong
Published: November 2022

Suicide can be defined as an act of self-injury with the intent to die. According to World Health Organization (WHO), it is estimated that more than 700 000 people end their life every year. Suicide becomes a critical social problem in recent years and it is one of the key reasons for death among university students. Generally, the prevalence of suicidal ideation among university students is ranged from 1.3% to 32.7% worldwide. Therefore, it is necessary to determine the risk factors for suicidal ideation among university students and rank them based on the significance level so that the students with these characteristics can be identified promptly and proper actions can be taken to help them. In this study, we had discovered 18 risk factors for suicidal ideation through systematic literature review and these factors were ranked based on the importance level using Analytic Hierarchy Process (AHP) method. As a result, we found that the most important factors that lead to suicidal ideation were prior suicide attempts, mental disorder and negative life events. In contrast, gender and residential area were the least important reasons for suicidal ideation. Thus, the implementation of AHP method enables us to compare various risk factors effectively.
On The Origin of Speciation
Authors: Hayashida Kenji
Published: November 2022

Charles Darwin proposed the theory of evolution that natural selection leads to the evolution of organisms in "On the Origin of Species”, but did not show the mechanism by which new species differentiate and fix. Speciation requires a system in which genes are not mixed by interspecific hybridization, and reproductive isolation, especially postmating reproductive isolation, is considered to be the most reliable as guarantee. Haldane proposed that heterogametic sex was absent, rare or sterile in interspecific hybrid F1. Dobzhansky and Muller predicted that postmating reproductive isolation occurs when mutations occurring at two or more interacting loci exhibit incompatibility in the hybrid. Genes that satisfy these observation and prediction are considered speciation genes. Here, I would like to review the findings on reproductive isolation and speciation to consider the candidate conditions for the speciation genes, and present the genes that fit these conditions.
Studi Pengaruh Powder Factor Terhadap Fragmentasi Peledakan Dan Produktivitas Alat Gali Muat Di PT. Ansaf Inti Resources Kabupaten Kutai Kartanegara Provinsi Kalimantan Timur
Authors: Lawangan Fernando , Oktavian Revia , Winarno Agus
Published: November 2022

One of the successes of a blasting is if the results of fragmentation are obtained with good size and relatively uniform so that the production target can be met. The size of the fragmentation was analyzed using Split Desktop 2.0 which resulted in a curve of the size of the fragmentation and the percentage of sieve pass (screening), at Pit 2 the optimal powder factor was between 0.20 kg/m³-0.26 kg/m³, while at Pit 7 it was between 0.22 kg/m³-0.24 kg/m³ which results in top size fragmentation in March 25.02 cm-43.2 cm, April April 35.37 cm-50.59 cm, May 19.79 cm-32.28 cm, June 26.45 cm-63.69 cm, which affect the digging time generated from the Komatsu PC 400 Excavator with an average top size fragmentation size of 38.33 cm with an average digging time of 7.95 seconds, while the Hyundai R 850 LC-9 Excavator with a fragmentation top size the average top size is 33.97 cm with an digging time of 8.44 seconds, with the average productivity of the Komatsu PC 400 Komatsu of 198.49 BCM/Hour from a plan productivity of 200 BCM/Hour while the Hyundai R 850 LC-9 average productivity a of 364.41 BCM/Hour from the plan productivity of 350 BCM/Hour
Penerapan Sistem Kesehatan Dan Keselamatan Kerja Menggunakan Metode Strenght Dan Weakness Di PT Energi Cahaya Industritama Samarinda Provinsi Kalimantan Timur
Authors: Musarofah Siti Fadlah , Winarno Agus , Magdalena Henny , Nugroho Windhu , Respati Lucia Litha
Published: November 2022

Research on the application of the OHS system is carried out with the aim of analyzing things in the application of K3. The research method uses a descriptive method in the form of a questionnaire. The results of the research questionnaire the highest percentage included in the strength (strenght) including the use of PPE 83.9% agreed that it was applied followed in an orderly manner, promotions and strategies and the application of K3 64.5% strongly agreed, the existence of PPE training that was applied 74.2% agree. The results of the weakness analysis (Weakness) that the highest percentage of the results of the questionnaire diagram are incomplete first aid facilities 80% agree, the workplace is not conducive, planning for implementing K3 strategies, providing emergency facilities for accidents 83.9%, periodic initial checks to employees 74.2% quite agree.
Effect Of Dawood's Fasting In Removing Total Blood Cholesterol Levels In Surabaya Hidayatullah Islamic Boarding School’s Student
Authors: Rahayu Indri Ngesti , Wijayanti Ni Luh Putu Ratih , Purwaningsari Diah , Komalasari Intan , Dagradi Eric Mayo
Published: November 2022

Background: Hypercholesterolemia is a risk factor for causing death at a young age. The World Health Organization reported in 2002 that 4.4 million deaths were caused by hypercholesterolemia, or 7.9% of the total number of deaths at a young age. Hypercholesterolemia is a condition in which cholesterol levels in the body exceed normal levels. One way that can be done to prevent hypercholesterolemia is to control diet, namely by fasting. Dawood’s fasting is one of the obligatory fasts of Islamwhich is done with one-day fasting and one-day not. Objective: This study aims to determine the effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.Methods: This study was designed with a quasi-experimental study research method using a comparative pre-test post-test non-equivalent control group design. The sample in this study was divided into two groups, namely one control group and one treatment group from the sample selected by purposive sampling. The population studied were students of the Hidayatullah Islamic Boarding School in Surabaya. Result: The results of statistical analysis using the Wilcoxon signed-rank test showed an effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.Conclusion: From research result that has been done, it can be concluded that there is an effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.

Keywords: Dawood’s fasting, total blood cholesterol.
Analisa Disturbance Fault Recorder ( DFR ) Sebagai Alat Perekam Anomali Pada Gardu Induk Rangkas Baru
Authors: Mira Des
Published: November 2022

Gardu induk pada UPT Cilegon ULTG RANGKAS merupakan gardu induk tegangan tinggi dan ekstra tinggi (GI/GITET) dengan kapasitas trafo terpasang mencapai 3810 / 895,5 MVA serta 1.568 tower penghantar transmisi dengan panjang jaringan mencapai 858,92 km sirkit merupakan sebuah sub sistem dari sistem transimisi tenaga listrik. Sebuah gardu induk tentu memiliki peralatan-peralatan yang menunjang kinerjanya, salah satunya adalah peralatan proteksi. Pentingnya penelitian ini dilakuakan karena sering terjadinya gangguan ( Noise ) pada saluran transmisi hal ini disebabkan beberapa factor salah satunya factor lingkungan sekitar,bencana alam dan lain-lain. Pada gardu induk, terdapat sebuah peralatan yang memonitor anomali dari arus, tegangan maupun frekuensi pada gradu induk. Peralatan tersebut dinamakan Disturbance Fault Recorder (DFR). Tujuan penelitian ini adalah menganalisa penggunaaan DFR dalam memonitor arus, tergangan dan frekuensi sebelum, saat dan setelah terjadinya anomali pada arus, tegangan dan frekuensi pada gardu induk.  Metode penelitian yang digunakan adalah pengamatan langsung pada Gardu induk rangkas , setelah melakukan pengamatan langsung penulis mencari sumber-sumber reverensi yang berkaiatan dengan DFR, setelah mencari referensi yang berkaitan penulis melakukan analisa di Gardu Induk Rangkasbitung . Setelah melakukan penelitian dapat disimpulkan bahwa penggunaan DFR pada Gardu Induk Rangkas Bitung dapat bekerja dengan baik hal ini dapat dilihat dari, nilai toleransi batas bawah pada pengaturan DFR adalah 46.4V. dan nilai toleransi batas atas pada pengaturan DFR adalah 69.6V.
Pemanfaatan Sistem Photovoltaic untuk Catu Daya Repeater Radio PLN
Authors: Sudewanto Suhardhika Sih , Kalatiku Erwin
Published: November 2022

The utilization of radio communication is one of several means to carry out electricity network coordination. The establishment of radio repeater is mandatory to cover vast areas of electricity system nodes. The radiation of a radio system is generally restricted by the contour of the terrain. The optimal location for radio repeater is usually situated in an isolated area, away from society. This will cause a problem in acquiring power supply from the local grid. This problem can be solved by harnessing solar power to energize the photovoltaic system. The implementation of the photovoltaic system will be done by performing load calculations of radio repeater equipment, determining the components needed, and executing site installation. With calculation result of 6,3 Days of Autonomy, the photovoltaic system is believed to be robust enough to increase the effectiveness of radio repeater operation.
Komparasi Output Termoelektrik Generator ( Kuat Arus Dan Tegangan ) Pada Jalas Aspal Dan Beton Dengan 3 Variasi Bentuk Plat Tembaga
Authors: Yazu Luthfi Afiif , Mainil Rahmat Iman , Aziz Azridjal
Published: November 2022

Solar radiation heat energy is energy that propagates throughout the earth's surface and is absorbed stored in various objects on the earth's surface. A thermoelectric generator is an electrical generator device that converts heat (temperature difference) directly into electrical energy, using a phenomenon called the Seebeck effect. In this research, this research was carried out by utilizing the absorption of solar radiation heat on a concrete road with a type of cast concrete class III with K 250 and asphalt type AC-WC as a thermoelectric generator. This research uses 3 thermoelectric generator modules type 1848 which will be arranged in series, the cooling system is filled with water using 2 asphalt and concrete variables, each of which has three variations of L, I and Z-shaped heat conductor plates. The test results show that asphalt has energy larger than concrete. L plate is the best plate on both asphalt and concrete roads. This research allows it to be developed to become a reference source of the latest alternative energy.

Keywords: Heat Energy, Thermoelectric generator, Plate variation
Pengaturan Kecepatan Motor Induksi 3 Fasa Dengan Metode V/F Konstan Dan Kontrol PID-CHR
Authors: Ibrahim Maulana Malik
Published: November 2022

Its sturdy construction and simple maintenance make the induction motor the main driving machine in the industry. Induction motor speed setting is one of the operating conditions that are often used so that an inverter 3 phase is needed as an induction motor speed regulator. Inverter 3 phase is a device used to make AC voltage 3 phase from dc voltage supply source. Inverter 3 phase used type Current Source Inverter that uses the Sinusoidal Pulse Width Modulation (SPWM) method with constant voltage / frequency control (v / f constant). In optimizing the motor response, it is used to control feedback with a low error rate, pid-CHR control is applied which can cover a wider range of operating conditions and is easily adjustable.
Rancang Bangun Prototype Kendali Lampu Dan Pemantauan Daya Listrik Menggunakan Node MCU Dan App Inventor Berbasis IoT
Authors: Zen Felani M , Alam Syah , Hutajulu Albert Gifson
Published: November 2022

Teknologi Internet of Things semakin hari semakin berkembang begitu pula pemanfaatan aplikasi di android tidak lagi hanya sebatas untuk komunikasi dan media sosial saja. Aplikasi android juga dapat dimanfaatkan sebagai kendali dan pemantauan berbagai perangkat sehari-hari yang berbasi Internet of Thing (IoT). Selain memanfaatkan aplikasi IoT berbasis android yang telah tersedia seperti Blynk, juga bisa membuatnya sendiri dengan memanfaatkan App Invertor buatan MIT (Massachusetts Institute of Technology). App Inventor adalah alat pengembangan yang digunakan untuk membangun aplikasi di Android. MIT menciptakan alat pengembangan yang mudah digunakan oleh siapa saja dengan menggunakan pendekatan blok.  Adapun desain layar dilakukan dengan pendekatan “Click & Drag”. Selain itu app inventor juga telah menyediakan komponen   database dari Firebase. Sehingga App inventor cocok digunakan untuk membuat aplikasi IoT berbasis android. Pada penelitian ini  penulis membuat aplikasi andoid untuk mengendalikan lampu dan memantau daya listrik terpakai yang berbasis IoT. Rancangan sistem meliputi hardware dan software. Hardware meliputi mikrokontroler NodeMCU sebagai pusat kendali, relai sebagai saklar lampu, modul PZEM-004T sebagai sensor pemantauan daya listrik. Rancangan software meliputi aplikasi android dan program mikrokontroler. Hasil perancangan adalah sebuah aplikasi android yang dapat digunakan untuk kendali lampu dan memantau daya listrik terpakai. Lampu dapat dikendalikan manual ataupun otomatis dengan timer. Sistem ini memanfaatkan koneksi internet yang terhubung baik pada smartphone android dan juga pada mikrokontroler
Prototipe Sistem Kendali Jarak Jauh Pada Pakan dan Pintu Kandang Kucing
Authors: Putri Tri Wahyu Oktaviana , Darmawan Muhammad Affan
Published: November 2022

Kucing merupakan hewan peliharaan yang sangat populer didunia. Dari banyaknya aktivitas pemilik kucing menimbulkan berbagai macam masalah pada kucing terutama pada kebutuhan pokoknya seperti makan, minum dan bermain diluar kandang. Perancangan prototipe ini tentang suatu sistem kendali jarak jauh pakan, minum dan pintu pada kandang kucing yang dapat dikontrol melalui aplikasi Blynk pada Smartphone. Prototipe ini menggunakan NodeMCU sebagai mikrokontroler sekaligus komponen penghubung keapliaksi Blynk. Pada pintu kandang kucing dikontrol dengan motor servo dan monitoring pergerakan kucing yang melewati pintu dengan sensor infrared yang akan dikirimkan notifikasi ke Blynk. Pada ketersediaan pakan dan minum dimonitoring dengan sensor ultrasonik melalui notifikasi pada aplikasi Blynk. Pemberian pakan dengan motor servo dan pemberian minum dengan pompa air mini dikontrol melalui aplikasi Blynk. Hasil dari perancangan, prototipe dapat mengontrol dan memonitoring pakan dan pintu kandang kucing dari jarak jauh yang dapat diakses realtime dengan delay 3-5 detik saja
La desobediencia civil. Una mirada filosófica al movimiento Fridayforfuture
Authors: Barona-Villafuerte Paulina
Published: November 2022

El presente trabajo titulado “La desobediencia civil. Una mirada filosófica al movimiento Fridayforfuture”, pretende analizar si el movimiento Friday For Future liderado por Greta Thunberg constituye un caso de desobediencia civil. Teniendo en cuenta que Friday For Future es un movimiento que principalmente pugna por la protección ambiental y generar cambio frente al caso omiso y pasividad de los gobiernos mundiales en la aplicación de políticas y leyes amparen medio ambiente, su activismo ambiental lo manifiestan protestando cada viernes, llamando la atención internacional, e inspirando a estudiantes, jóvenes y demás personas a lo largo del mundo, a secundar su iniciativa y a participar en huelgas y protestas. Por lo tanto, las características del movimiento Friday For Future cumple con las condiciones necesarias para que ser un claro ejemplo de desobediencia civil, ya que, es una acción colectiva, pública, ilegal, pacífica, en contra de un orden jurídico específico injusto e inmoral y busca el cambio de los gobiernos mundiales en la aplicación de políticas y leyes que realmente protejan el ambiente. En este contexto en el presente artículo se abordan como principales puntos de discusión 1.- La desobediencia civil; 2.- Breve repaso histórico; 3.- Greta thunberg: concienciación de masas y desobediencia civil. Fridayforfuture; 4.- Greta thunberg: un año para cambiar el mundo, el documental. La metodología utilizada fue la cualitativa al realizarse un análisis teórico sobre el tema objeto de estudio y se consultó la bibliografía relacionada con la temática, con la finalidad de alcanzar mayor comprensión del tema e interpretar adecuadamente los diferentes conceptos utilizados.
Análisis de la legislación internacional relativa a crímenes de guerra con ocasión del conflicto entre Rusia y Ucrania
Authors: Recalde-Jácome Jeniffer , Portillo-Cabrera Jesús
Published: November 2022

Este trabajo reflexiona sobre el conflicto armado internacional entre Ucrania y Rusia analizando la posibilidad de que los altos mandos militares de estos Estados sean juzgados internacionalmente por los eventuales crímenes de guerra que se presenten con ocasión a la confrontación armada. La guerra ruso-ucraniana suscita amplio interés en la comunidad internacional ya que existe una creciente preocupación por las denuncias de infracciones graves al Derecho Internacional Humanitario, DIH, por lo que reflexionar sobre la posibilidad jurídica de eventuales sanciones individuales por crímenes de guerra constituye un tema actual y relevante. En tal sentido, aplicando una metodología de revisión documental cualitativa, el artículo describe la normativa internacional referente a este tipo penal y analiza si los Estados involucrados la han ratificado o no, para presentar algunas conclusiones que dan cuenta de la preocupante probabilidad de que no haya sanciones internacionales debido a la falta de competencia de la Corte Penal Internacional.
Principios constitucionales vulnerados en el ámbito laboral en el tiempo de la covid-19
Authors: Ramírez-Castro Wendy
Published: November 2022

Se puede recalcar las consecuencias sin precedentes del impacto mundial por motivo del COVID 19, resultando en una emergencia sanitaria, conforme a las disposiciones implementadas por los países en materia de atención y contención, enfocando la vigencia del manto tutelar  de los derechos humanos.

En el contexto contemporáneo existe una validez en el texto constitucional y normativo respecto a los derechos humanos amparando a todos los ciudadanos, en situaciones que sitúan en peligro a bienes jurídicos como la vida, salud y situación jurídica antes de la propagación del COVID 19; Se desprende que a mediano y largo plazo el interés común, y en particular respecto a las personas y colectivos susceptibles de vulneración de derechos.
El valor de marca (Brand Equity) en la intención de compra a través de canales digitales de las tiendas de abarrotes de la ciudad de Machala en tiempos de post pandemia
Authors: Palomino-Banegas Cinthia , Tigrero-Guncay Tania , Tinoco-Egas Raquel
Published: November 2022

La equidad de marca tiene un papel importante al realizar una compra juegan varios factores el objetivo de esta investigación es identificar el valor de la marca en la intención de compra a través de canales digitales en las tiendas de abarrotes de la ciudad de Machala en tiempos de post pandemia esta investigación analizó a 70 participantes entre hombres y mujeres de 18 a más de 50 años de edad considerados como población económicamente activa de la ciudad de Machala. Muchos de las tiendas de abarrotes han pasado por una difícil situación después de la pandemia ya que su clientela ha disminuido esto permitió investigar el valor de la marca que tiene cada consumidor al realizar una compra, en donde se ha añadido elementos como la Conciencia de marca, Igualdad de Marca, Asociación de marca y Lealtad de marca esto permite saber cuál es el factor que más influye en el consumidor para adquirir su producto en los diferentes supermercados que lo ofrecen ya sea por los precios, como por la facilidad de pago y las promociones que hay en dicho lugar. Estos hallazgos son importantes para el sector comercial en donde gerentes de supermercados podrán verificar que influye en su compra.
La reclamación por violación de derechos a los oferentes en la calificación de ofertas de los procesos de subasta inversa electrónica en el Azuay – 2021
Authors: Alvarado-Miranda Cristian , Vega-Crespo Elizabeth
Published: November 2022

En muchos procesos de contratación pública se pueden presentar inconvenientes por parte de aquellas personas que sienten una afectación  por parte de los sujetos de contratación pertenecientes al Estado, en virtud de lo cual, pueden presentar reclamaciones debidamente motivadas ante “el Servicio Nacional de Contratación Pública, (SERCOP)”. Este estudio tiene por objetivo conocer y comprobar la existencia de violación de principios y derechos de los oferentes en la calificación de dichas ofertas en concursos de contratación pública mediante subasta inversa electrónica. La metodología de este artículo se dio con base a los métodos cuantitativo e histórico para verificar las etapas del tema planteado para corroborar la hipótesis planteada. También, se realizó una revisión documental para recopilar información respecto a la temática planteada, la misma que se obtuvo del “SOCE”. Los resultados encontrados, indican que las reclamaciones que presentan los proveedores interesados, se ven afectados en las fases de este y por las antinomias entre “la Ley Orgánica del Sistema Nacional de Contratación Pública y su Reglamento General”, considerando que las etapas del procedimiento precluyen y no se realiza el procedimiento del reclamo con celeridad quedando muchas veces en la indefensión adjudicando el proceso sin haber resuelto la reclamación.
Administración pública digital e inteligente desde la perspectiva del gobierno abierto. Caso de estudios GAD Provincial de Manabí
Authors: Parrales-Carrillo Rosa , Vegas-Meléndez Hilarión
Published: November 2022

El propósito de la investigación fue el interpretar los principios del gobierno abierto que dan impulso a una administración pública digital e inteligente en el GAD Provincial de Manabí (Ecuador); el enfoque metodológico ha sido cualitativo, apoyada  en el método inductivo, cuyo nivel de profundidad es de tipo descriptiva, con un trabajo de campo no experimental, la revisión documental ha servido de estrategia para el sustento del discurso por parte de los investigadores; además, como estrategia de análisis la misma se basó en las fases propuestas por la Teoría Fundamentada (Strauss y Corbin) diseñada para casos de estudios; por otro lado, el método hermenéutico (analítico-interpretativo) contribuyó con la identificación del objeto de estudio al permitir darle una forma compresiva e interpretativa a partir del discurso expresado por los informantes claves -académicos e investigadores- mediante una entrevista semi estructurada (en profundidad). Entre los hallazgos encontrados se encuentran tres vertientes que dan oportunidad a una idea de buenas praxis dentro de la gestión del GAD Provincial de Manabí; estas vertientes sean generado a raíz de un proceso de categorización a partir de una muy cuidadosa triangulación discursiva: teóricos, informantes e investigadores, estas vertientes son: Gobierno abierto democrático, Estado abierto y Modelo de gobernanza abierta y colaborativa. Sin dudas, se hace necesario abrir paso a una administración pública digital e inteligente, pertinente para gestionar la complejidad del presente.