bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Moringa Oleifera. Lam Leaf Extract on Bcl2 and Bax Expression in Paracetamol-induced Renal Tubular Apoptosis in Rats
Authors: Jannah Miftahul , Subagyo Djoko Trihadi Lukmono , Nasihun Taufiqurrachman
Published: April 2023

BACKGROUND: Paracetamol may cause apoptosis in the renal tubules. Moringa leaf (Moringa oleifera. Lam) has been shown to have antioxidant effects due to its f lavonoids. In addition, f lavonoids also have biological effects to modulate the signal-transduction pathway.OBJECTIVE: to investigate the effect of Moringa oleifera Lam extract on Bcl-2 and Bax expression on paracetamol-induced renal tubular injury.METHODS: in this post-test only control group design study, 24 rats were divided into 4 groups: AqC-G (aquades), EtC-G (70% ethanol), MoL1-Gand MoL2-G (moringa leaf extract at the dose of 1.075 g/Kg BW and 2.150 g/Kg BW respectively). Expression of Bcl2 and Bax was determined using immunohistochemical staining. The data on the number of Bcl2 and Bax expressions tested with One Way Anova followed by the Post Hoc LSD test.RESULTS: Post Hoc LSD test showed that the expression of Bcl-2 in the experimental groups ((MoL1-G (9.1) and MoL2-G (13,683)) was significantly higher compared to that of controls (p<0.001). Bax expression in the experimental groups (MoL1-G (6,85) and MoL2-G (2,633)) was significantly lower compared to that of controls, p <0.001.CONCLUSION: The administration of Moringa leaf extract at the dose of 1,075 and 2,150 increases Bcl-2 expression and decreases Bax expression in paracetamol-induced renal tubular injury.
Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
Authors: Wijayanti Heni , Nasihun Taufiqurrachman , Hussaana Atina
Published: April 2023

BACKGROUND: Mung bean, not only contains protein, carbohydrates, and fats, but also contains iron and vitamin C which are proven to overcome anemia in pregnant woman. High iron levels are potential to increase ROS production through fenton reaction.OBJECTIVE: to prove the administration of mungbean can increase Hb and ferritin levels and decreasing malondihaldehyde (MDA) in anaemic rats.METHODS: This research uses Post Test Only Control Group Design. A total of 25 anaemic rats were divided into 5 groups: normal group (Nor-G);negative control group (Neg-G), were given low Fe diet; and treatment group with low Fe and mung bean extract at dose of 0,18g/200g/days (GP-0,18), 0,36g/200g/days (GP-0.36), dan 0,72g/200g/days (GP-0.72). Low Fe diet and mung bean extract were administered for 14 days. Hb levels were measured using Sahli method, ferritine level using Immulite Ferritine Kit, and MDA were measured using TBA.RESULTS: Compare to Nor-G and Neg-G, levels of ferritin and Hb on groups with mung bean extract 0,18g (75.56), 0,36g (90.98) and 0,72g (95.87) were significantly higher (p < 0.05). While MDA levels on groups with mung bean 0,18g (4.646), 0,36g (3.396) and 0,72g (1.92) were significantly lower than on Nor-G and Neg-G groups (p < 0.05).CONCLUSION: The administration of mung bean extract can increase Hb and ferritin, also lower MDA level on anaemic rats.
Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
Authors: Widyaningrum Naniek
Published: April 2023

Background: To date, green tea leaf waste is not well utilized, the waste is remain considered as a waste. Previous studies found that green tea leaf waste still have a fairly high EGCG content. EGCG has benefits as an antibacterial. Utilization of green tea leaf waste started from formulation until the diversification of multiple emulsion w/o/w products has not been reported.Objective: To develop anti acne cream (W/O/W) multiple emulsion containing green tea leaf waste and evaluate its antibacterial activity against acne-inducing bacteria of Propionibacterium acnes (P.acnes).Methods: Phase one of this research was green tea leaves was extracted by infundation and fractionation method using ethyl acetate and prepared in different concentration (1% to 6%). The second stage was ethyl acetate fraction of green tea leaf extract was tested for its antibacterial activity against P.acnes. Third stage was tested physical properties of formulation with w/o/w multiple emulsion.Results: The optimal antibacterial activity of ethyl acetate fraction of green tea leaf extract against P.acne was at the concentration of 6%, with inhibition zone of 32.6 mm ±0.57. The formula of w/o/w multiple emulsion loaded with green tea leaves waste of 6% active substance demonstrated a good physical properties which can spread 90.4 cm2 ± 0.03, pH 5.00 ± 0.02 and microscopic analysis showed multiple emulsion w/o/w.Conclusion: The concentration of 6% green tea leaf waste formulated in multiple emulsion had a good physical and antibacterial activity for a referred standard. It is necessary to test the stability of multiple emulsion formula.
Results Characteristics of Lipid Profile Examination of Acute Ischemia Stroke Patients at RSUP Dr. Soedono Madiun, East Java
Authors: Wuryani Dinik , Darumurti Rissito Centricia
Published: April 2023

Introduction: Dyslipidemia as reflected in the results of lipid profile examination is among the most common abnormalities found in acute ischemic stroke patients. Studies assessing the characteristic of these results may provide a foundation for an effective plan of treatment and prevention to overcome the burden of the disease.Objective: To study the characteristic of the results of lipid profile examination among acute ischemic stroke patients at Dr. Soedono General Hospital, Madiun, East Java.Methods: This research is a descriptive study with a cross-sectional approach using secondary data taken from the medical records of acute ischemic stroke inpatients at the Stroke Unit of Dr. Soedono General Hospital, Madiun, East Java admitted in January-December 2015. Results of lipid profile examination consisting of total cholesterol, LDL, HDL, and triglycerides were categorized as high, normal, and low based on their respective levels.Results: There were 72 subjects selected using simple random sampling. Level of total cholesterol was high in 52.78%, normal in 36.11%, and low in 11.11% of the subjects. Level of LDL was high in 54.17%, normal in 22.22%, and low in 23.61% of the subjects. Level of HDL was low in 31.94%, normal in 50.00%, and high in 18.06% of the subjects. Level of triglycerides was high in 26.39%, normal in 33.33%, and low in 40.28% of the subjects.Conclusion: Total cholesterol and LDL are generally high, HDL is generally normal, while triglycerides is generally low among acute ischemic stroke patients in Dr. Soedono General Hospital, Madiun, East Java.
Strangulated Femoral Hernia With Perforated Jejunal Pseudodiverticula : a Case Report
Authors: Ekasaputra Vito
Published: April 2023

Introduction: Sixty percent of femoral hernias are characterized by incarceration and strangulation. Jejunal pseudo diverticulum are rare and usually asymptomatic. It may cause chronic obstruction of small bowel and can lead to an acute perforation.Case presentation: An 85 – year – old woman presenting with 1 week history of generalized abdominal pain, with episodes of vomiting, fever, and history of 6 months of reponible femoral hernia and 2 weeks strangulated of femoral hernia. An abdominal X-ray displayed multiple dilated loops of the small bowel, coil spring sign and intra peritoneal free air. This  patient underwent a laparotomy and hernioraphy, which identified single perforated jejunal pseudo diverticulum 50 cm from ligamentum of treitz orally from strangulated of ileal on femoral hernia site, and associated fecal contamination. The management for this case was perforation repaired with diverticulectomy, simple closure, and extensive washout of intraperitoneal cavity. The non tension femoral hernia repair was performed with monofilament, macroporous MESH.Conclusion: chronic intestinal obstruction caused by femoral hernia in the elderly can lead a performed of intestinal pseudo diverticulum and lead to significant morbidity and mortality. This could be suspected in those presenting with cramping abdominal pain and altered bowel habits.Keywords: hernia, femoral, strangulated, pseudo diverticulum, perforated, management
Corneal Curvature Measurements Utilizing a New Swept-source Optical Coherence Tomography Tomey OA-2000® and Comparison With IOL Master® 500 in Pterygium Patients
Authors: Hilmi Mohd Radzi , Mohd Kamal Khairidzan , Che Azemin Mohd Zulfaezal , Ithnin Mohd Hafidz , Md Mustafa Md Muziman Syah , Yusof@Alias Firdaus , Ahmad Norsham
Published: April 2023

Introduction: Corneal curvature (CC) is an important anterior segment parameter. This study compared CC measurements conducted with two optical devices in pterygium eyes.Methods: Sixty pterygium eyes of 30 patients were enrolled in this study. CC was measured three times with the optical biometer and topography-keratometer Tomey OA-2000 (Tomey Corporation, Nagoya, Japan), then with partial optical coherence interferometry (PCI) IOL Master 500 (Carl Zeiss Meditec, Dublin, CA) and data were statistically analysed.Results: The measurements revealed in a mean CC of 43.86 ± 1.57 D with Tomey OA-2000 and 43.84 ± 1.55 D with IOL Master. Distribution of data is normal, and no significance difference in CC values was detected (P = 0.952) between the two devices. Correlation between CC measurements was highly significant (r = 0. 99; P < 0.0001). The mean difference of CC values between devices was 0.017 D and 95% limit of agreement was -0.088 to 0.12. Duration taken for measurements with the standard biometer IOL Master was longer (55.17 ± 2.24 seconds) than with Tomey OA-2000 (39.88 ± 2.38 seconds) in automatic mode. Duration of manual measurement with Tomey OA-2000 in manual mode was shorter (28.57 ± 2.71 seconds).Conclusion: In pterygium eyes, CC measured with Tomey OA-2000 and IOL Master showed similar values, and high correlation was observed between these two devices. This shows that both devices can be used interchangeably. Tomey OA-2000 is better in terms of faster to operate and has its own topography systems.
O tabu da morte e a prevenção do suicídio nas universidades federais
Authors: Pimentel Rangel Kock Graciella
Published: April 2023

A Organização Mundial de Saúde propôs um plano de Ação para Saúde Mental com meta de redução em 10% da taxa global de suicídio. O Brasil tornou-se signatário desse planejamento e implementou uma Agenda de Ações Estratégicas para a Vigilância e Prevenção do Suicídio e Promoção de Saúde, para o quadriênio 2017-2020. Nessa proposta, o segmento da educação foi inserido como ator e agente de intervenção, dado que o número de extermínio da vida atinge também crianças, jovens adolescentes e universitários. Diante disso, este artigo analisa como 15 universidades federais das regiões Sudeste e Sul do Brasil atuam[1] na prevenção do suicídio dos membros da comunidade acadêmica e apresenta sugestões para a implementação de um Programa de Prevenção do Suicídio para a Universidade Federal do Espírito Santo (Ufes).

Palavras-chaves: universidade; suicídio; prevenção.
Promoção de Fonoaudiologia Educacional no enfrentamento da pandemia COVID-19 na Secretaria de Educação da Prefeitura Municipal de Vila Velha
Authors: Ferreira Santos João Ricardo , Mapa Silva Igor , De Souza Conceição Bianca , Biancardi Carneiro Eduarda , Rafaela dos Santos Gomes Ellen , Soares Pontes Karina , Brunoro Motta Loss Alessandra , Fiorin Anhoque Comarela Carolina , Silva de Albuquerque Guiomar , Perroud Miller Liliane , Neves Pessoa Almeida Aline , Alves Maia Andréa
Published: April 2023

O Programa Saúde na Escola (PSE) propicia ações de integração entre Saúde e Educação. A pandemia da COVID-19 impactou o sistema de ensino, pelas necessidades de readaptações no processo de ensino e de aprendizagem. A partir da demanda da equipe de fonoaudiólogas do PSE da Prefeitura Municipal de Vila Velha (PMVV), elaborou-se este projeto com objetivo geral de promover a fonoaudiologia educacional, com estratégias remotas de prevenção e intervenção nos processos de comunicação e de aprendizagem da leitura e da escrita. Os principais resultados obtidos foram: formação continuada dos professores; elaboração e compartilhamento de materiais informativos e educativos, nas temáticas sobre saúde e educação, relacionados ao processo de enfrentamento das consequências da pandemia COVID-19 no sistema de ensino e de aprendizagem. Os indicadores avaliados pelo levantamento de demandas, o apoio e acompanhamento da gestão local e as avaliações durante o processo mostraram novas perspectivas dos educadores, diante de atuais realidades das temáticas expostas. Conclui-se que as atividades realizadas tiveram impacto positivo para a educação pública do município, a partir de novos posicionamentos dos professores, com olhar para as competências do estudante conforme possibilidades do contexto econômico, político e social.
Apresentação
Authors: Pinheiro Ramos Fabiana
Published: April 2023

Apresentação da edição n° 15 da Revista de extensão Guará.
Variation of Processed Fresh Pineapple on Vitamin C Content Using UV-VIS Spectrophotometry
Authors: Mardiana Prasetyani Putri
Published: April 2023

Important sources of vitamin C in food mainly come from fruits and vegetables. One type of fruit that contains vitamin C and is much in demand by the public is pineapple. To extend the shelf life of pineapple fruit can usually be done by processing the fruit into other preparations. But on the other hand the content of vitamin C in fruit and food will be damaged due to the oxidation process by the outside air, especially when heated. This study aims to determine the levels of vitamin C in fresh pineapple and processed varieties of pineapple. This research method is descriptive by analyzing the content of vitamin C in fresh pineapple and its processed variations using the UV-Vis spectrophotometry method. Based on the results of the study, the levels of vitamin C in fresh pineapple, pineapple syrup and candied pineapple were (95.75 ; 49.09 ; 44.09) mg/100g, respectively. Based on the statistical test results, a significant value of p>0.05 was obtained, which meant that the data was normal and continued with the paired parametric T test. The result of the test is p<0.05. There are differences in the value of vitamin C levels in fresh pineapple and processed variations.
Influence of Zebularin on Antioxidant Enzymes and Lipid Peroxidation of Galleria mellonella (Lepidoptera: Pyralidae)
Authors: ÇAKIR Ebru , UÇKAN Fevzi , ERGİN Ekrem , ÖZBEK Rabia
Published: April 2023

Cytosine methylation is a process that adds a methyl group to a cytosine residue of DNA to convert it to 5-methylcytosine. Zebularine (ZEB) reactivates hypermethylated genes in yeast and solid tumor cells, with DNA methyltransferases that show a preferential effect on cancer cells. We investigated the effects of various doses (0.25-32 mg/ml) of ZEB, on antioxidant enzyme activity and lipid peroxidation in wax moth Galleria mellonella last instars. Injection of ZEB in last instars G. mellonella resulted in increases in SOD, MDA, and GST levels, in order of magnitude, but not in CAT enzyme activity. Two possible reasons were predicted for these results. This effect could be a result of the inhibitory effect of ZEB on DNA methylation in G. mellonella, which leaded to reducing gene transcription in insects. Or it was likely that high oxidative stress might cause a decreasing activity of enzymes.
Pricing in Road Freight Transport
Authors: Poliak M. , Lachmetkina N. Yu.
Published: April 2023

Creation of price in road freight transport in Central Europe has undergone significant changes in the last 30 years. Transporters in regulated economy used mandatory tariffs, after the liberalisation of the market they were subsequently not prepared for their own price creation. Price calculation has gone through several stages of development. At present, there are existing cost calculations that are based on the division of costs into variable and fixed ones. After the accession of Central European countries to the European Union, competition in this sector has increased significantly. When calculating the price for transport, transporters use a coefficient of exploitation of journeys, which adjust the costs associated with the transport so that the costs also take into account the journey with the vehicle, which the transporter must carry out without the shipment.The aim of this paper is to prove that from the point of view of the competitiveness of price creation it is not economically correct to use the coefficient of exploitation of journeys as a constant coefficient. The authors prove in the article that the value of the coefficient depends not only on the route of consignment transport but also on the time of transport realisation.
ChatGPT in physics education: A pilot study on easy-to-implement activities
Authors: Bitzenbauer Philipp
Published: April 2023

Large language models, such as ChatGPT, have great potential to enhance learning and support teachers, but they must be used with care to tackle limitations and biases. This paper presents two easy-to-implement examples of how ChatGPT can be used in physics classrooms to foster critical thinking skills at the secondary school level. A pilot study (n=53) examining the implementation of these examples found that the intervention had a positive impact on students’ perceptions of ChatGPT, with an increase in agreement with statements related to its benefits and incorporation into their daily lives.
Sliding Mode Vibration Suppression Control Design for a Smart Beam
Authors: Hamzah Mohsin N. , Al-Samarraie Shibly Ahmed , Abdulsahib Imad Abdulhussein
Published: April 2023

Active vibration control is the main problem in different structure. Smart material like piezoelectric make a structure smart, adaptive and self-controlling so, they are effective in active vibration control. In this paper piezoelectric elements are used as sensors and actuators in flexible structures for sensing and actuating purposes, and to control the vibration of a cantilever beam by using sliding mode control. The sliding mode controller (SMC) is designed to attenuate the vibration induced by initial tip displacement which is equal to 15 mm.  It is designed based on the balance realization reduction method where three states are selected for the reduced model from the 24th states that describe the cantilever beam according to the FEM. These states are most controllable and observable. The stability and control performance for the proposed SMC are proved using candidate Lyapunov function and the equivalent control concept. The control spillover, which is the sources of instability, is completely avoided as ensured within the control performance proof.

            Numerical simulations are preformed to test the vibration attenuation ability of the proposed SMC. For 15 mm initial tip displacement, the piezoelectric actuator was found able to reduce the tip displacement to about (0.2) mm within (2.5 s), while it is equal to (3.5) mm with the open loop case. Moreover, the induced chattering in system response, due to the discontinuous control action, is removed by approximating the signum function by a continuous arctan function. As a result  a smoother response are obtained with the same control performance as can be shown in the sliding variable, the control input voltage and the tip displacement plots.
Improvement of Traffic Movement for Roads Network in Al-Kadhimiya City Center
Authors: Ismael Mohammed Qadir , Mohammed Ali Jasim
Published: April 2023

Numerous regions in the city of Baghdad experience the congestion and traffic problems. Due to the religious and economic significance, Al-Kadhimiya city (inside the metropolitan range of Baghdad) was chosen as study area. The data gathering stage was separated into two branches: the questionnaire method which is utilized to estimate the traffic volumes for the chosen roads and field data collection method which included video recording and manual counting for the volumes entering the selected signal intersections. The stage of analysis and evaluation for the seventeen urban roads, one highway, and three intersections was performed by HCS-2000 software.The presented work plots a system for assessing the level of service for roads network within the study region. Moreover, several improvement alternatives were proposed to overcome the traffic movement operations issues. This work shows that traffic facilities currently undergoing serious degradation causing a traffic jam. Therefore, the implementation of some remedial action is necessary to improve the level of service for these facilities.
Calculating the Transport Density Index from Some of the Productivity Indicators for Railway Lines by Using Neural Networks
Authors: Mohamed Sawsan Rasheed , Burhan Abbas Mohammed Mohammed , Hadi Ahmed Mohammed Ali
Published: April 2023

The efficiency evaluation of the railway lines performance is done through a set of indicators and criteria, the most important are transport density, the productivity of enrollee, passenger vehicle production, the productivity of freight wagon, and the productivity of locomotives. This study includes an attempt to calculate the most important of these indicators which transport density index from productivity during the four indicators, using artificial neural network technology. Two neural networks software are used in this study, (Simulnet) and (Neuframe), the results of second program has been adopted. Training results and test to the neural network data used in the study, which are obtained from the international information network has showed that the error rate in the training and the testing process was about (10%) and that the results of the network query has given the results of acceptable accuracy statistically so that it was better than results obtained from multiple linear regression equation for the same data.
O papel de uma legislação penal mais responsável na redução do fluxo de entrada no sistema prisional
Authors: Homerin Janaina Camelo
Published: April 2023

O presente artigo chama a atenção para a parcela de responsabilidade do poder legislativo no agravamento do colapso da realidade carcerária no Brasil. Iniciamos com um breve panorama da atuação do legislador em prol do endurecimento da lei penal que resulta na ampliação da porta de entrada para o sistema de justiça criminal. Em seguida, o artigo destaca algumas propostas de alteração legislativa que têm o potencial de desafogar o sistema. No entanto, aponta que fatores estruturantes moldam o funcionamento do sistema de justiça e influenciam a eficácia da legislação penal. O fio condutor dessa análise observa a interação entre os poderes legislativo e judiciário, marcada pela visão de que um bom processo penal é o que resulta em prisão. Conclui-se que mudanças legislativas são necessárias, porém insuficientes para reverter a lógica encarceradora que conduziu à insustentabilidade da política criminal brasileira. Enfrentar a massificação do encarceramento exige a pactuação de uma política pública consistente que inclua, mas não se restrinja, à competência legislativa.
O sentimento de insegurança e a armadilha da segurança privada: reflexões antropológicas a partir de um caso no Rio Grande do Sul
Authors: Barroso Priscila Farfan
Published: April 2023

O presente trabalho reflete sobre os acionamentos da defesa de uma empresa de segurança privada, investigada pelo Ministério Público do Estado por supostas irregularidades e atuação de poder abusivo por parte dos envolvidos. Esses acionamentos são ponderados com base em relatos de moradores de um município do Rio Grande do Sul, feitos nas redes sociais, que, a partir da evidência do sentimento de insegurança, apostam na permanência dessa empresa como uma possibilidade para segurança. Com isso, analisam-se os argumentos de “falta” de segurança pública nas cidades e o temor da violência urbana, compartilhados pelos moradores, como justificativas de possibilidade de contratação da empresa. Entretanto, após sua “queda”, a disputa entre esses argumentos revela o pano de fundo para a reflexão sobre segurança pública. Violência urbana, medo e aval dos órgãos públicos são atributos que possibilitam a instalação – ou não – da segurança privada.
O Centro Integrado de Comando e Controle: ferramenta de coordenação, integração e planejamento na defesa social
Authors: Soares Philipp Augusto Krammer , Batitucci Eduardo Cerqueira
Published: April 2023

Os Centros Integrados de Comando e Controle (Ciccs) foram concebidos como parte do planejamento nacional de segurança para os grandes eventos que o Brasil receberia entre os anos de 2013 e 2016. O Cicc é uma ferramenta recentemente introduzida na máquina pública brasileira com o objetivo de facilitar e incrementar o desenvolvimento das atividades relacionadas à segurança pública em ocorrências de alta complexidade no país. Após a Copa do Mundo, um dos supracitados eventos, os Ciccs tiveram de ser absorvidos pelas estruturas estaduais onde se encontravam. Sendo assim, este estudo tem como intuito observar a atuação do Cicc em Minas Gerais e visa traçar os caminhos a se seguir para que seja possível um diagnóstico preciso do que tem sido feito, como tem sido feito, as metas atingidas e não atingidas, as dificuldades e os desafios desse órgão.
Lakly village surroundings – one of the key territories of the UNESCO Yangan-Tay Geopark sustainable development
Authors: Danukalova Guzel , Sokolov Yuryi , Polezhankina Polina , Osipova Evgeniya
Published: April 2023

The paper describes the characteristics of the natural features of the northwestern part of the Southern Urals, near the transition zone of the advanced ridges of the Urals to the band of the Urals. Administratively, the territory covers the vicinity of the village of Lakly in the Salavatsky district of the Republic of Bashkortostan and is part of the UNESCO Yangan-Tau Geopark. The description of unique geological and geomorphological objects is given. The necessity of properly informing the population about the importance of natural objects, the need for careful attitude to them and environmental education, as well as the involvement of this territory in the network of tourist excursion routes, the directions of its development are given.
Mineralogy of ores of the Vosneenskoe gold deposit (Southern Ural)
Authors: Znamensky Sergei Evgenievich , Znamenskaya Nina Michailovna
Published: April 2023

The mineralogical features of the ores of the Voznesenskoye gold deposit located in the zone of the Main Ural Fault at the northern end of the Magnitogorsk megazone of the Southern Urals have been studied. The chemical composition of minerals was determined using a Tescan Vega Compact scanning electron microscope with an Oxford Instruments Xplorer 15 energy dispersive analyzer. Two stages of ore formation have been identified and characterized. On the early of them, arsenic pyrite (0.38–0.84% As), which is the main mineral of ores, was first formed, and later sulfurous arsenopyrite (S/As = 1.12–1.19), molybdenite enriched in Fe (7.25–8.07%), and chalcopyrite. Using an arsenopyrite geothermometer, it was found that the formation of sulfides at an early stage occurred approximately in the temperature range of 318–380°C. At a late stage, an association was formed that united pyrite containing Sb (0.28–0.31%), Zn-Fe-tetrahedrite (Cu9.1–9.4 (Fe1.2–1.3 Zn1.1–1.4)2.4–2.6 (As0.2–0.4 Sb3.7–4.1)4.2–4.3 S12.9–13.2) and native high-grade gold (952–997‰) with impurities Ag and Cu. Minerals of this association, which have an insignificant distribution, are found in crushing zones developed in arsenic pyrite. In terms of chemical composition, the studied tetrahedrite is close to the fahlores of the subepithermal mineralization of the Mikheevka porphyry Cu deposit. Based on the results of the studies performed, a preliminary conclusion was made that the Voznesenskoye deposit belongs to the subepithermal type of gold mineralization.
Histopathological and immunohistochemical investigation of primary avalvular varicose anomalies (PAVA) in a patient with primary varicose veins and PAVA
Authors: Whiteley Mark Steven , Bankowska Antonina , Santos Scott J Dos , Ashpitel Henry F , Salguero-Bodes F. Javier
Published: April 2023

Background:Primary avalvular varicose anomalies (PAVA) are found in 4.6% patients with primary varicose veins and can be confused with neovascular tissue. These veins can be found in all compartments of the leg and are found more commonly in patients with pelvic venous reflux. Little is known about these atypical vessels and so we are reporting the histopathologic features of PAVA compared to a typical varicosity.Methods:A section of PAVA was removed under ultrasound guidance from a patient undergoing routine endovenous thermoablation for varicose veins, along with several varicosities extracted by phlebectomy. Venous tissue was fixed in buffered formalin and underwent routine histological processing into paraffin wax. Sections were cut 4 microns thick and were stained with haematoxylin and eosin (H&E), Martius Scarlett Blue (MSB) and immunohistochemical staining for smooth muscle actin (SMA). Stained sections were examined by a board-certified pathologist.Results:PAVA showed distinct differences from “normal” varicose veins. There were multiple protrusions into the lumen of the abnormal vessel, due to an irregularly enlarged media. The media was rich in collagen and there was a reduction in the smooth muscle cells found circumferentially throughout the media and adventitia. Varicosities removed by phlebectomy appeared normal, with all three tunicae clearly visible. Conclusions:Although the samples only came from one patient, they showed clear differences histologically PAVA and “normal” varicose venous tissue. This early report needs to be confirmed in a larger sample of patients and more work is needed to understand the exact derivation of PAVA.
SENAT fst 2018
Authors: SIANTURI HERY LEO
Published: April 2023

Dalam rangka meningkatkan mutu pelayanan dosen khususnya Tridarma perguruan tinggi diperlukan pengakuan kinerja sehingga dosen yang bersangkutan dapat meningkatkan kinerjanya.
Labil dalam Perspektif Hadis
Authors: Muzakki M. Ash Shaff
Published: April 2023

Manusia merupakan makhluk yang selain memiliki fisik, pancaindra, dan akal pikiran, juga memiliki fitrah, hati nurani, dan spiritualitas Keadaan fisik, pancaindra, dan akal pada hakikatnya merupakan kendaraan yang mengikuti keinginan hati nurani dan spiritual Jika keadaan hati nurani dan spiritualnya positif, maka sesuatu yang akan dilakukan oleh fisik dan pancaindra, serta yang dikeluarkan oleh akal pikiran juga positif dan seterusnya oleh karena itu, apabila manusia melakukan perbuatan yang tidak berdasarkan nilai-nilai positif, maka manusia tersebut mengingkari identitasnya sendiri Nabi melihat. mimpi: Menceritakan seseorang Muhammad bin Hatim bin Maimun, menceritakan kepada kami Ibn Mahdi, dari Mu'awiyah bin Salih, dari 'Abd al-Rahman bin Jubair bin Nufair, dari bapaknya, dari al-Nawas bin Sim'an al-Ansari berkata: saya bertanya kepada Rasulullah saw. tentang kebaikan dan dosa, maka beliau merasakan: kebaikan adalah akhlak yang mulia, sedangkan dosa adalah sesuatu yang menggelisahkan jiwa, dan dosa tersebut akan terlihat buruk ditengah-tengah manusia perlu diuraikan bahwa manusia pada dasarnya diberikan dua potensi, yaitu potensi akal dan hati Oleh sebab itu, apabila seseorang hendak menghindari dari dosa maka segala tindakannya harus berdasarkan pembenaran hati (iman) Pada prinsipnya, kelabilan terjadi pada seseorang yang melakukan dosa, karena sebenarnya seseorang tersebut mengetahui bahwa perbuatannya tersebut salah
PENERIMA MANFAAT DAN FASILITATOR PEMBERDAYAAN MASYARAKAT
Authors: MUH.WAHYU.M
Published: April 2023

Studi ini bertujuan untuk menemukan apakah pemberdayaan masyarakat merupakan proses pembangunan yang memberdayakan masyarakat untuk membangun program aksi sosial untuk memperbaiki keadaan dan kondisi mereka sendiri. Jika masyarakat itu sendiri yang berpartisipasi, maka pemberdayaan masyarakat dapat terjadi .Jadi, pada hakekatnya, istilah “pemberdayaan” mengacu pada upaya kolaboratif antara motivator, fasilitator, dan organisasi masyarakat yang memerlukan pemberdayaan melalui peningkatan kemampuan, peningkatan pengetahuan, dan penyediaan berbagai sarana dan kesempatan dalam rangka atau mewujudkan suatu sistem sumbu sumber daya. dalam meningkatkan kesejahteraan rakyat. Karena tidak semua individu di setiap negara, wilayah, atau bahkan lingkungan menikmati standar hidup yang sama, maka pemberdayaan masyarakat menjadi sangat penting. Oleh karena itu, bantuan yang diberikan oleh pihak luar kepada mereka yang belum mampu mandiri harus bersifat otonom, yang memungkinkan untuk memberi manfaat bagi masyarakat sementara mereka berusaha untuk mandiri sepenuhnya. Dengan kata lain, mentalitas mereka perlu dikembangkan agar dapat berfungsi dengan baik dan sesuai dengan tuntutan mereka.
Telaah Hadis tentang Keutamaan Orang dalam Menuntut Ilmu
Authors: Diyanna Diyanna
Published: April 2023

Menuntut ilmu merupakan kewajiban bagi setiap muslim terutama karrna banyak keutamaan yang bisa kita dapat dalam menuntut ilmu. Dalam melakukan takhrij hadis banyak hal yang perlu dilakukan mulai dari mencari potongan hadis kemudian mencarinya di kitab mujam muffaras dengan kata kunci unik. Metode yang digunakan pada artikel ini yaitu librari reaserch dengan metode bi lafzi. Hasil yang didapatkan dari artikel ini yaitu potongan hadis tentang keutamaan menuntut ilmu yang dicari menurut kitab mujam muffaras terdapat pada kitab At-Tirmidzi pada bab ilmu pada bagiaj keutamaan menuntut ilmu, maka setelah itu dapat ditelusuri lebih lanjut terkait hadis lengkapnya beserta rijal hadis dan jarh wa tadil dari sanad-sanad pada potongan hadis tersebut.
Face Recognition based on Discrete Wavelet Transform and Euclidean Distance
Authors: Tena Silvester , Maggang Amin A. , Unu Imanuel A. D.
Published: April 2023

A face recognition application consists of feature extraction and face identification process. The two processes have been widely used as methods for recognizing various faces. The challenge in face recognition is how a face recognition application could recognize faces with expressions, poses and facial structures that always changes by age and emotion. This research aims to compare wavelet family, Haar and Daubechies (at the maximum level of decomposition), as they are used for feature extraction on a face recognition application. Furthermore, Euclidean distance (ED) was utilized in the application as face identification method. The developed system has 240 face images in its database, collected from 40 different people with 6 different types of expression for each person. The results show that the developed application is able to produce success rate and accuracy of recognition up to 95% from 80 tested images. Haar Wavelet, at fifth decomposition level, shows the best performance as it could produce minimum feature vector while maintaining the success rate and accuracy at 91.25%.
Designing digital library as a facilities to support Open and Distance learning (ODL) student: a case in Universitas Terbuka Indonesia
Authors: Limbong Asnah Marlina Nellawaty
Published: April 2023

The aim of this study is to elaborate the effectiveness of digital library to support open and distant learning students. Digital libary is required to support Open and Distance Learning (ODL) students to get learning materials in their learning process. This descriptive study involved Students Expert of IT, Librarians as respondents. The respondents provided information and data regarding the use of the digital library to support their learning process. Observation and interview were used as a technique for collecting data and information. Besides, this study used secondary data is related to the objective of the study-to elaborate the effectives of using distance learning in ODL. The result of this study is indicated that the majority of the open and distant students used the components of availbale digital library such as Virtual Reading Room (RBV), e-repository, e-resource and Open Education Resource (OER) to upport their learningactivities
Senat FST 2014
Authors: SIANTURI HERY LEO
Published: April 2023

Dalam rangka meningkatkan mutu pelayanan dosen khususnya Tridarma perguruan tinggi diperlukan pengakuan kinerja sehingga dosen yang bersangkutan dapat meningkatkan kinerjanya.
MOTIVASI ATLET AEROBIC GYMNASTIC PROVINSI RIAU DALAM MENGIKUTI LATIHAN SELAMA MASA PANDEMI COVID-19
Authors: Effendi Annisa , Wijayanti Ni Putu Nita , Vai Aref , Ittaqwa
Published: April 2023

Latihan merupakan proses dengan adanya interaksi antara pelatih dengan atlet. Pada saat  latihan ada faktor psikologis yang juga perlu dirangsang dilatih dan dikembangkan, salah satu faktor tersebut yaitu motivasi. Permasalahan yang terjadi dimasa pandemik covid-19 ini, atlet harus melakukan latihan secara mandiri, ini artinya tidak ada intereaksi antara pelatih dan atlet. Oleh karena itu penelitian ini bertujuan untuk mengetahui  tingkat motivasi atlet aerobik gymnastic Provinsi Riau dalam mengikuti latihan selama masa pandemik covid-19. Jenis penelitian yang digunakan adalah deskriptif kuantitatif. Instrument dalam penelitian berupa angket dengan validitas 0,950 dan realibitas nilai cronbach’s alpha> 0,6. Sampel penelitian adalah atlet aerobik gymnastic Provinsi Riau berjumlah 6 orang. Teknik analisis data menggunakan aplikasi IBM SPSS Statistic. Hasil  analisis data pada pembahasan diketahui bahwa tingkat motivasi atlet dalam mengikuti latihan selama masa pandemik covid-19 termasuk dalam kategori baik dengan persentase 77,36% dari total keseluruan sub variabel individu.
Pengaruh Waktu Hauling Terhadap Hasil Tangkapan Bagan Perahu di Pelabuhaan Perikanan Pantai Carocok Tarusan Sumatera Barat
Authors: Prasetyo Agung , Bustari Bustari , Nasution Polaris
Published: April 2023

Pengaruh waktu hauling terhadap hasil tangkapan bagan perahu bertujuan untuk menentukan jumlah dan jenis hasil tangkapan berdasarkan waktu hauling dan menentukan waktu hauling yang paling optimal untuk melakukan penangkapan serta untuk dapat mengetahui ada atau tidaknya pengaruh waktu hauling terhadap hasil tangkapan. Kapal bagan di PPP Carocok Tarusan melakukan penangkapan pada periode hauling malam hari mulai dari pukul 18.00-24.00 WIB, dan dilanjut lagi mulai dari pukul 00:00-06.00 WIB. Hasil perhitungan menggunakan uji T didapat hasilnya yaitu 0,95. Maka hipotesis yang digunakan adalah terima H1, yang artinya terdapat pengaruh hasil tangkapan dalam waktu penangkapan sebelum dan sesudah tengah malam. Sehingga dapat diketahui bahwa waktu penangkapan yang paling optimal untuk melakukan penangkapan yaitu pada waktu setelah tengah malam
Kajian Selektivitas Gillnet pada Penangkapan Ikan Biang (Ilisha elongata ) di Desa Alai Kabupaten Kepulauan Meranti
Authors: Ginting Feliz Nafidad , Brown Arthur , Nofrizal Nofrizal
Published: April 2023

Konsumsi ikan setiap tahun akan meningkat di iringi semakin padatnya jumlah manusia. Kebutuhan akan ikan sangat tinggi karna ikan mengadung banyak protein yang baik untuk tubuh manusia, hal ini menjadi faktor sehingga minat untuk konsumsi ikan sangat tinggi. Penelitian ini bertujuan mengukur tingkat selektivitas jaring biang, menganalisis tingkat selektivitas gillnet, serta mengetahui hubungan antara ukuran morfometrik tubuh ikan dengan cara tertangkapnya ikan. Penelitian ini dilaksanakan pada bulan Januari s/d Februari 2021. Metode yang digunakan adalah metode experimental fishing. Adapun hasil yang didapat yaitu gillnet alat tangkap selektif terhadap ikan biang. Pada mesh size 3 inci semakin tinggi ukuran hasil tangkapan (di atas 20 cm) semakin rendah rasio penangkapan sedangkan pada mesh size 4 inci semakin tinggi ukuran hasil tangkapan (di atas  20 cm) semakin tinggi rasio penangkapan. Kategori hubungan terkuat yaitu hubungan body girth dan cara tertangkap gilled, dari hasil regresi fork length dan cara tertangkap, kategori hubungan terkuat yaitu fork length dengan snagged dan pada hubungan antara body girth dan cara tertangkap sangat rendah dan juga hubungan antara fork length dan cara tertangkap sangat rendah dan hampir tidak memiliki hubungan
Knowledge and practice regarding retinopathy of prematurity among paediatricians
Authors: Shrestha Priyanka , Mathema Smriti , Pradhan Pranil Man Singh
Published: April 2023

Background: Retinopathy of prematurity, a vision threatening disease of the preterm occurs due to abnormal retinal vasculature development. Early detection and timely management, prevents blindness. Paediatricians, the primary care providers, require good knowledge of risk factors, time for screening, and referral to an ophthalmologist for their management.
Objectives: To study knowledge and referral practices for retinopathy of prematurity followed by registered paediatricians in Nepal.
Methods: This study was a questionnaire-based descriptive cross-sectional study among 81 paediatricians of Nepal from October 2021 to December 2021. A self-administered questionnaire was sent to all registered paediatricians in Nepal via Google Forms. The paediatricians who did not respond were excluded from the study. Descriptive statistics, frequency tables, and percentages were calculated using SPSS. Ethical clearance was obtained from Institutional Review Committee of Kathmandu Medical College.
Results: Eighty-one paediatricians participated in the study. All of them were aware of retinopathy of prematurity. Eighty (98.8%) were aware that low gestational age was an important risk factor. Only 23 (28.4%) of the paediatricians stated that the first screening should be done within 30 days of life. Eighty (98.8%) paediatricians responded that retinopathy of prematurity is treatable. Lack of well-equipped transportation system for sick babies to eye centres was the major barrier reported.
Conclusion: Awareness regarding risk factors, screening, and referral protocols for retinopathy of prematurity among paediatricians is needed. Multidisciplinary team, formulation and implementation of guidelines to prevent blindness secondary to retinopathy of prematurity is important.
Functional outcome of long-arm cast versus double sugartong splint in acute paediatric distal forearm fractures: A randomised controlled trial
Authors: Banjade Deepak , Adhikari Sushan , Adhikari Rabindra , Tamang Ramesh Syantan , Dahal Saroj Chandra , Lamichhane Megha Raj
Published: April 2023

Background: The treatment of choice for paediatric distal forearm fractures has been a long-arm cast (LAC) following closed reduction. An alternative treatment is to use a double sugar-tong splint (DSTS), found equally effective to provide three-point fixation and comparable outcomes to cast. Objectives: To compare the functional outcome between LAC and DSTS for the treatment of paediatric distal forearm fractures. Methods: A randomised controlled trial was done among 36 patients of 5-15 years with acute distal forearm fractures without neurovascular deficit treated with LAC and DSTS recruited by convenience sampling at a tertiary care centre after ethical approval. Acceptability of reduction, loss of reduction, union rates, cast comfort, range of motion and complications were studied at follow-up upto 12 weeks and analysed using SPSS v.11.5. Results: Among a total of 36 patients, 18 cases were treated by the LAC method and others by the DSTS method. Both LAC and DSTS were comparable in the maintenance of reduction, the remanipulation rate was 8.3% (n = 3), not significant (p-value = 0.967). All had a union at six weeks follow-up. No statistical difference in mean VAS score (p-value = 0.524), mean loss of flexion (p-value = 0.397), and mean loss of pronation/supination (p-value = 0.814). No statistically significant difference in activities of daily living was noted. No complications were encountered. Conclusion: DSTS is safe and as effective as LAC in the treatment of distal forearm fractures in children, identical in terms of functional outcome, maintenance of reduction, complications, and time to union.
Comparison of left ventricular global longitudinal strain by speckle tracking echocardiography in patients with and without diabetes mellitus asymptomatic for coronary artery disease at a tertiary hospital in Nepal
Authors: Shrestha Sanjaya Kumar , Khadka Tunam , Shrestha Anmol Prasad
Published: April 2023

Background: Diabetes mellitus is a major risk factor for cardiovascular events. A significant proportion of diabetics are asymptomatic for ischaemic heart disease either because of the early stage of ischaemia or silent myocardial ischaemia. Global longitudinal strain (GLS) of the left ventricle measured by speckle tracking echocardiography (STE) is a novel method of detecting left ventricular dysfunction due to myocardial ischaemia. Objectives: This study aimed to compare the GLS of type-2 diabetes mellitus (T2DM) and non-diabetic patients who were asymptomatic for coronary artery disease (CAD). Methods: An analytical cross-sectional study was conducted among 52 diabetic and 49 non-diabetic individuals asymptomatic for CAD presenting to a tertiary hospital, between 2022 September to 2022 October. The STE was performed to measure left ventricular GLS of the participants. Their blood and urine samples were sent for measuring glycosylated haemoglobin (HbA1c), total cholesterol, and microalbuminuria. Data were entered and analysed using SPSS v23. Results: Twenty-five (48.1%) diabetics had left ventricular dysfunction (GLS ?18) compared to two (4.1%) non-diabetics. GLS was significantly lower among the diabetic patients, and exhibited significant inverse correlation with the duration of diabetes, age, HbA1c, and microalbuminuria (p <0.001). In multiple linear regression model for GLS, only the duration of diabetes (B = -0.27, p <0.001) and the age of patients (B = -0.057, p = 0.004) retained statistical significance, after adjusting for other covariates. Conclusion: Left ventricular GLS has a significant negative correlation with the duration of diabetes and age of the patients.
Three Dimensional Printing: An innovation in Otorhinolaryngology Practice
Authors: Shrestha Bikash Lal
Published: April 2023

No abstract available.
Managing Heart Failure with Preserved Ejection Fraction; A Short Review of Latest Evidences
Authors: Mahaseth A. , Karki P.
Published: April 2023

Heart failure with preserved ejection fraction (HFpEF) is a clinical dilemma and various clinical trials so far have failed to give a concrete evidence of reducing mortality and major adverse cardiac events (MACE) in this condition. A detailed analysis of the existing evidences and a future plan for a concrete trial design with long duration of follow up is needed to address the dilemma of Heart failure with preserved ejection fraction.

The objective of this short review was to review the latest and major randomized controlled trials and study the primary outcomes. The public database of PubMed, Google Scholar and Cochrane were extensively searched for all randomized controlled trials using keywords of Heart failure with preserved ejection fraction, major adverse cardiac events, Hospitalizations; and studies were included in the review if data were reported for patients with ejection fraction > 40%, did not include congenital heart disease, and demonstrated evidence of diastolic failure on echocardiogram (ECHO), and evaluated hospitalizations, major adverse cardiac events and cardiovascular mortality.

Despite the major trials reporting improved primary composite endpoints with newer drugs the results have to be interpreted cautiously since the primary outcome were mostly driven by heart failure hospitalizations and not mortality reduction.
The Process of Acquiring Political Relevance of Law and Justice Elections
Authors: Budny Michał
Published: April 2023

Political relevance is one of the most essential elements of political subjectivity. The process of its acquisition by political parties is not only a factor of their success, but also the foundation of their ability to influence the sphere of current politics. The political relevance of political parties combines both the institutional dimension of political processes and the practice of competition in three dimensions: electoral, parliamentary and cabinet. Only when parties are able to participate in all the three dimensions will they be able to perform the most important functions. The following article presents a specific dimension of acquiring political relevance, which is the management of political change.