bluuebunny/crossref_metadata_2025 huggingface dataset:
Mandatory Pre-trial Procedure for the Settlement of Disputes in Civil Procedure (Analysis of the Application of Part 5 of Article 4 of the Arbitration Procedure Code of the Russian Federation)
Authors:   West Siberian Branch of the Russian State University of Justice, Kniazev D. V. , Kukartseva A. N. ,   National Research Tomsk State University (Tomsk)
Published: April 2021

The provisions of the arbitration procedural legislation on the pre-trial procedure for the settlement of the dispute are additional requirements to the filing to the court in comparison with civil procedural legislation. According to the legislator, on the one hand, these requirements encourage the independence of commercial organizations and individual entrepreneurs in the settlement of economic disputes, on the other hand, indicate the desire of the legislator to reduce the number of arbitration disputes and increase the effectiveness of justice. About three years have passed since the appearance of the norm in question and some conclusions can be drawn regarding its application by the courts. The authors of the article draw attention to the problematic aspects of law enforcement practice: categories of disputes when the application of pre-trial procedure is mandatory; compliance with the form, content, deadlines for submitting a claim; assessment by the court of the actions of the parties to resolve the dispute before going to court; overall effectiveness of the existing order. The authors conclude that the goal set by the legislator before the pre-trial procedure (an alternative pre-trial method for the resolution of disputes, designed to provide faster, less formalized and costly dispute resolution in comparison with the judicial process) is not achieved.
Legal Disputes on the Assessment of Customs Value: Trends in the Courts Rulings
Authors:   Russian State University of Justice (Moscow), Matvienko G. V.
Published: April 2021

The article presents the findings of scientific and practical analysis of court decisions made following the review of disputes on the assessment of customs value over the past few years. The author comes up with suggestions aimed at improving legislation and unification of law enforcement practice in Russia and throughout the territory of the Eurasian Economic Union.
Features of Foreclosure on the Salary of a Citizen-Debtor
Authors:   Kazan Branch of the Russian State University of Justice (Kazan), Bezina A. K. , Vaiman A. B.
Published: April 2021

In the article on the level of theory, legislation and judicial practice are analyzed following contradiction: on the one hand, the bailiff as an enforcement authority the power conferred upon him by law functions (article 68, 98 of the Federal law N 229-FZ) is not entitled and obliged to foreclose on the debtor»s income; on the other hand, even when setting minimum retention percentage of such income remaining amount from the debtor of the earnings will be below the value required to maintain a minimum level of security. When foreclosing on such income, the rights of the debtor to maintain the necessary minimum of funds will be violated, and in the case of refusal to foreclose on income, the rights of the claimant, confirmed by a court act that has entered into force, will be violated.
Judicial Reconciliation – a Novel in the Procedural Legislation of the Russian Federation
Authors:   Russian State University of Justice (Moscow), Zhenetl S. Z. , Bzegezheva N. S. ,   Supreme Court of the Republic of Adygea
Published: April 2021

The article is devoted to the study of novels, introduced into the procedural rules, regulating alternative reconciliation procedures, the issues concerning the legal status of the judicial mediator, introduced into the procedural legislation, are analyzed in detail. The article describes the main directions in the application of alternative reconciliation procedures in particular foreign countries. Attention is drawn to a number of wishes for improving some of the rules, governing judicial reconciliation procedure.
Robotization of Judicial Activity
Authors:   Russian State University of Justice (Moscow), Fursov D. A.
Published: April 2021

Robotization of judicial activity is understood as the creation of state courts online based on artificial intelligence. The use of other digital technologies is considered only as a prerequisite for the transition to robotic administration of justice, and the readiness of technologies and users themselves to electronic document management. This article discusses the main reasons for misconceptions about the irreplaceability of a person in the judge»s chair, as well as all the advantages and opportunities that are inherent in the constantly developing software product called artificial intelligence.
Legal Acts and Legal Agreements in the Legal System
Authors:   Russian State University of Justice (Moscow), Ershov V. V.
Published: April 2021

The article analyses both general scientific and special research methods, including comparative legal and historical legal methods. The following conclusion was made: In accordance with the scientifically grounded concept of the integrative understanding of law, objective law is primarily expressed in its principles and norms contained in a single, evolving and multilevel system of forms of national and/or international law implemented in the state, traditionally in legal acts and legal agreements in the modern period.
Psychological Aspects in Terms of Physical, Mental and Sociological Factors During Worldwide Corona Crisis
Authors: Akanksha Mandal
Published: April 2021

Severe acute respiratory syndrome is a viral disease affecting the respiratory system , cause by coronavirus.The epidemic lasted for 2 years till May 2004 when WHO declared China to be free of new cases but statedthat “ biosafety concerns remain” In 2019, SARS-CoV-2 was discovered which later in the present havecaused the COVID-19 pandemic. The first case was identified in Wuhan, china and which later on turnedto worldwide pandemic. The WHO had declared the outbreak a public health emergency of internationalconcern on 30 January 2020 and a PANDEMIC on 11th march 2020.Considering the present scenario , there are certain articles over the internet and journals which have givenus a bunch of ideas over different aspects of life. Some of the long list of concepts are physical health, mentalhealth, local market uprising, and concept of work from home .Based on gathered information via discussions, surveys and personal interactions with thousands ofindividuals, differing in age, by gender and by occupations, these hereby key points and key lessons havecome to light and here is a brief description in terms of physical health , mental health, effect of lockdownon local market and effect of work from home on people.
Combined Effect of Neural Tissue Mobilization and Deep Friction Massage in Piriformis Syndrome: A Research Protocol
Authors: Vrushali K. Athawale  , Divya Jethwani  , Moh’d Irshad Qureshi  , Ragini Dadgal
Published: April 2021

Background:- Piriformis syndrome is the musculoskeletal condition which is characterized by pain alongwith tingling and numbness which results because of compression of piriformis muscle. Various treatmentapproaches are present for treating the piriformis syndrome but neural tissue mobilisation is manual therapysimilar to joint mobilisation. Deep friction massage is used to breakdown adhesion and release of scartissues. This study protocol has been created to find out the combined effect of neural tissue mobilizationand deep friction massage in piriformis syndrome.Methods:-- On the basis of inclusion and exclusion criteria 30 participants between 20-60 years of agehaving piriformis syndrome will be select for study and are classified into two groups. Group A (n-15) forNeural Tissue Mobilisation, Group B (n-15) for Neural Tissue Mobilisation and Deep Friction Massage.Outcome measure are Oswestry Disability Index, Numerical Pain Rating Scale and Range of motion of hipjoint. Follow up of the participants are done after every 2 days and treatment duration is of 10 days.Discussion:- Effect of intervention will be analyzed by Numerical Pain Rating Scale, Oswestry DisabilityIndex and Range of Motion of Hip joint. The result of this study will significantly provide the affirmation ofNeural Tissue Mobilisation with Deep Friction Massage in Piriformis Syndrome.
Study of Mortality Due to Thoraco-Abdominal Injuries in Road Traffic Accidents in Mangalore City
Authors: Abymon K K  , Mohd Amjad Bhat  , Azia Manzoor Bhat
Published: April 2021

Background: After the strict implementation of helmet rule the number of head injuries due to road trafficaccidents has subsequently decreased, but injuries sustained to thoracic and abdominal regions are stillon the rise. This post mortem study of profile of thoraco-abdominal injuries, type, pattern and nature ofexternal and internal injuries involved will be an attempt to highlight the trends of mortality due to thoracoabdominal injuries associated with road accidents in Mangalore city. Material and Methods: Present studywas autopsy record based retrospective study conducted deaths associated with thoracic-abdominal injuriesthat have definite history of road traffic accidents. Results: From 247 deaths of RTA victims who sustainedthoraco-abdominal injuries, most common age group was 20 – 29 (21.8%) years, male: female ratio was 5.6:1. 21 % of cases were spot dead or dead on arrival to hospital, 60 % of cases died within 24 hours. 68.8%cases had thoracic trauma with signs of external injuries such as abrasions (60.7%), contusion (10.5%) andlaceration (10.2%). External abdominal injuries were present on 54.2% cases, 48.9% cases had abrasionfollowed by contusion in 8.9% cases and laceration in 6.5% cases. 199 (80.6%) cases sustained internalinjuries to thorax. Fractures of ribs were present on 59.5% cases. Injuries to lungs sustained in 37.2% casesand to heart in 22.6% cases. 136 (55.1%) cases of internal abdominal injuries, most common organ injuredwas liver (38%), followed by spleen (17%) & abdominal wall (14%). Among the 247 cases, cause of deathin 47% cases was head injury followed by thoraco-abdominal injury (20%), head injury and thoracic injury(8%), only thoracic injury (7%), abdominal injury (6%). Conclusion: The present study maximum numbersof the victims were males, from age group of 20-39 years, reported on city roads, pedestrians, noted insummer season and cause of death was head injury followed by thoraco-abdominal injuries.
Assessment of Anxiety during COVID-19 Pandemic among General Population of India
Authors: Anamika Gautam  , Poonam Ahlawat  , Shikha Sharma Thapa
Published: April 2021

Introduction -The coronavirus COVID-19 illness makes a very unpredictable future the main psychologicaleffect is elevated rates of anxiety, because of pandemic and the lockdown.Aim -The aimed of the study was to Assess the level of anxiety during COVID-19 among general populationin India.Methodology -A Snowball sampling technique was used to collect the samples from different state andunion territory of India. Total 829 participants respond and enrolled themselves in the study. Participants inthe study belong to 27 states or union territories of India and majority of them are from Delhi.Result-Most of the Participant in the study was female (54%), graduate (51%), age between 18-28 (60%)and Hindu (89.3%). Half of the participant were having minimal anxiety (57.1%) nearly one fourth ofthe participant were having Mild anxiety (28.5%) and least number of participants were having Moderateanxiety (11.0%) and Severe anxiety (3.5%).There was no significant association of Anxiety scores withSocio-demographic variable except place of stay, suffering from any health problem and During lockdownperiod time spent in watching news related to corona (COVID-19) on mobile, laptop, television etc.Conclusion-The study concluded the outbreak of coronavirus disease 2019 (COVID-19) Cause anxietyamong the people. Understanding the risk to yourself and people you care about can make an outbreak lessadverse effect on mental and physical health of the people
Comparative Study of Magnesium Sulphate added to Bupivacaine and Ropivacaine Local Infiltration of Wound for Postoperative Analgesia in Patients Undergoing Upper Abdominal Surgery: A Randomized Double Blind Study
Authors: Anuja Agrawal  , Sujay Thakkar  , Akhilesh Chhaya  , Malini Mehta
Published: April 2021

Aim: To compare subcutaneous infiltration of Inj Bupivacaine with inj MgSO4and Inj Ropivacaine withInjMgSO4 for postoperative analgesia undergoing upper abdominal surgery. Goal: To determine duration ofanalgesia, doses of rescue analgesia, VAS at different time intervals.Background: Post-operative pain is most neglected entity. We should use availableresources inoptimummanner for improving pain managementstrategies.Methods: A Prospective, double-blinded, randomized studyof 50 patients undergoing upper abdominalsurgery divided into group B and R. Infiltration was done in the subcutaneous plane by surgeon before skinclosure. Group B: Inj. Bupivacaine 50mg (10ml of 0.5% Inj . Bupivacaine) with Inj.MgSO4 500mg (1ml ofInj 50% MgSO4) diluted with NS 9 ml to make total volume of 20 ml whereas, Group R: Inj Ropivacaine50 mg (6.7 ml of 0.75% Inj. Ropivacaine) with Inj MgSO4 500 mg diluted with NS (12.3 ml) making a totalvolume of 20 ml. In postoperative period, parameters noted were vitals and Visual Analogue Score (VAS)for 24 hours.Results: In group R, moderate pain was seen in 40%of the patients at T12 whereas in group B 48% hadmoderate pain. Total no. of rescue analgesic doses required in Group R is 2.1 +/- 0.5 and in Group B is 2.6+/- 0.5 in 24 hrs and has significant differencestatistically.Conclusion: Group R had better VAS scores at T24 and reduced no.of rescue analgesic doses.
Effectiveness of Warm Water Foot Bath Therapy on Quality of Sleep among Elderly
Authors: Arati Raut  , Gunjan Morade  , Dnyaneshwari More  , Sanjivani Mune  , Pratiksha Munjewar  , Mayuri Mute
Published: April 2021

Background: Insomnia is a subjective complaint of inadequate night-time sleep. It is the most prevalentsleep disorder identified by older people.1Depression, anxiety, and reduced cognitive function have been linked with severe lack of sleep. Poor sleepquality in the elderly reduces the quality of life, but sadly the most elder people do not report sleep problemsunless expressly requested. Warm water foot bath provides a better sleep at night, as it calm downs andrelaxes the body and mind. This works by increasing the body temperature slightly and after 15 minutes thisstarts to drop gradually. This may indirectly encourage sleep. Gradual decrease in body temperature makesus feel drowsy and so we feel better prepared for sleep. A warm water foot bath also diverts some blood fromthe head to lower parts of the body, decreases brain activity and mimics the state of pre-sleep.2 We wanted todetermine the effectiveness of warm water foot bath therapy on quality of sleep among elderly.Methods: In this study the 60 older adults are selected based on inclusion criteria and were assigned toexperimental and control group alternatively. The experimental group composed of 30 elder people andcontrol group contained 30 elder people. The researcher developed rapport with older people receiving warmfootbath and explained the benefits of intervention. The day we began the data collection, the demographicdata and pretest took from elder people of experimental group and control group. On the next day, warmfootbath was given by the researcher with duration of 15 – 20 minutes for five consecutive days in olderpeople of experimental group. On the other hand, routine work is maintained in control group. Posttest wasdone on sixth day for both experimental and control group to assess the sleep quality among elderly by usingGroningen Sleep Quality Scale.4Results: Findings shows that 25 sample (83.33 %) had undisturbed sleep at night, 5 (16.67 %) had disturbedsleep at night using warm water footbath therapy and none of them had poor sleep at night. The minimumscore was 2 and the maximum score was 7 and the mean score was 4.23 ± 1.30 with a mean percentage of30.2 %. There significant association between qualities of sleeps and age group.Conclusions: The significant difference between preexisting sleeping quality and effectiveness footbathinterpreting effective quality of sleep using warm water footbath therapy among elderly. Mean value ofpreexisting sleeping quality is 8.93 and effectiveness of footbath therapy is 4.23 and standard deviationvalue of preexisting sleeping quality is 0.828 and effectiveness of footbath is 1.305. The calculated t-valueis 14.75 and p-value is 0.000. Hence it is statistically interpreted that the effectiveness of footbath therapyamong elderly was effective
Effect of Grey Zone Samples Testing by Enzyme Immunoassay and Its Impact on Enhancing Blood Safety: Experience from Tertiary Care Hospital based Blood Bank in Central Gujarat
Authors: Ashu Dogra  , Devanshi Gosai  , Jasmin Jasani
Published: April 2021

Background : Enzyme linked immunosorbent assay is a standard protocol adopted by majority of BloodBanks for screening of blood units for transfusion transmissible infections. The grey zone testing of samplesincreases sensitivity of ELISA tests which in turn enhances the safe blood transfusion practices. The presentstudy was thus designed to know the effect of repeat testing of Grey zone Blood Donor samples forimproving the sensitivity of ELISA Screening methods in blood banks.Methods:- All Blood Donor Samples which were 10% below the cut- off value were marked as Grey zonesamples and were repeated for ELISA screening . Interpretation of Repeat tests was done as per NACO andWHO guidelines and the samples which recorded their one or both O.D value above cut- off were labelledas reactive and samples which recorded one or both O.D value in grey zone were marked as indeterminate.Results and Conclusion: In present study, a total of 10,425 Blood Donors were screened for TTI’ s andout of 10,425 (15) Blood donor samples were found in grey zone. The results of repeat testing showed that9 (60%) Blood Donor samples were found to be confirm reactive for TTI. Grey zone sample testing shouldbe done routinely as a measure to enhance sensitivity of ELISA testing of Blood Donors in developingcountries.
Multifaceted Physiotherapeutic approach in Snapping Hip Syndrome: A Case Report
Authors: Deepali S. Patil  , Shivani R. Uttamchandani  , Pratik Phansopkar
Published: April 2021

Introduction: Snapping hip syndrome or “coxa saltans,” sometimes called as dancer’s hip, is seen in balletdancers. It is a condition caused by the movement of tendon or a muscle over a bony eminence in the hip inwhich snapping sound is heard or snapping sensation is felt when a person walks, runs, swing leg aroundor get up from a chair. Snapping Hip Syndrome is just associated with the snapping sound and no suchdiscomfort or pain is felt. Patients chief complaints were Low back pain radiating down her right leg andsometimes a click sound heard in her right hip. Experts estimate that 5 to 10 percent of the population hassnapping hips with no symptoms or pain, and no treatment is necessary. On the other half some individualshas irritating pain which requires treatment or surgery. Diagnosis of External Snapping Hip Syndrome wasconfirmed when detail evaluation of patient was done using Special test - SLUMPS and Straight Leg Raise(SLR) test, Faber’s test and Ober’s test and Harris Hip Score was also noted.Conclusion: This case report provides a comprehensive rehabilitation plan that helped relieve pain, spasm,increase strength and range of motion. Physiotherapy intervention includes stretching of the tighten muscleand purposeful strengthening to decrease pain and disability of patient. Physiotherapy treatment is foundto be best to resolve patient’s chief complaints. Improving the disability and Social skill improvement waschecked by using Lower Extremity Functional Scale (LEFS) and Quality of Life (QOL).
Utility of the Cell Block Preparation as an Additive Tool to the Conventional Cytological Smears
Authors: Devanshi Gosai  , Kuntal Patel  , Ashu Dogra  , Jasmin Jasani
Published: April 2021

Background: For the detection of malignancy in the serous fluids of the body, cytological examination ofthe fluid is very important. It is also of prime importance and seems difficult to differentiate the malignantcells from reactive mesothelial cells during fluid cytology. The cell block preparation is a useful and additivediagnostic tool when cellular features in cytology are inconclusive or suspicious. The aim of the study wasto assess the utilization of the cell technique as an additional tool along with the conventional smears thatwe are using in routine practice.Methods: 200 body (effusion) fluids were examined by the conventional cytological smears as well as bythe cell block technique.Conclusion: The diagnostic yield increases when we use the cell block preparation method along with theconventional smears because the architectural patterns and cell morphology are very well preserved in cellblock as compared to the smears.
Self Medication in Dentistry
Authors: Harshada Ragunathan  , Krithika C  , Kiruthiga G  , Keerthana S  , Lakshmipriya S  , PS Gayathri
Published: April 2021

Background: During mid 1980’s World Health Organization gave approval for some medical drugs fromprescription to reduce the burden of the medical professionals. Self-medication is one form of medicationwhich is practiced worldwide by many people with or without medical knowledge. In dentistry the mostcommon reason for taking the self-medication is phobia towards the dental procedures.Aim and Objective: This study was conducted to assess the knowledge about self-medication practiceamong common people and create awareness on its ill effects.Materials and Methods: A cross-sectional study was conducted among general population of age 18yearsand above. As the study was conducted during the pandemic time, a web-based survey was conducted witha set of 11 self-structured questions which was framed in English language and vetted with expert`s opinion.The questions were circulated through links to the participants through various social media platforms.Result: The 50 participants were grouped based on occupational status. chi-square test was performed andit was seen that most of the questions were statistically significant (p < 0.05). High significance was seenwhen the participants were asked the commonest reason and drug that they would prefer for self-Medication(p <0.00001).Conclusion: The common reason for using of self-medication in dental issue is pain, lack of time andphobia. This has to be improved by conducting awareness programs and the patients have to overcome theirfear and volunteer themselves to treat the cause.
Dissection of Learning Opportunities and Obstacles While Learning Through Video Conferencing Platform (VCP) - During Covid 19 Lockdown
Authors: Jyoti  , Khina Sharma  , Jyoti Sarin
Published: April 2021

Background- COVID 19 pandemic has influenced our lives in all the aspects, even the younger generationsare also not left untouched, specially their studies. Professional courses like nursing has integrated theorywith practical learning and due to the lock down situation both aspects of learning - theory as well asthe clinical learning are suffering. Though the teaching institutes have come up with the solutions likeonline lectures, using the video conferencing platform (VCP). This has expanded the horizon of traditionalclassroom. Though it is widely practiced in developed countries but in India it is still a new trend of learning.Purpose - of this study was to assess learner’s satisfaction level while learning through video conferencingplatform and various opportunities and obstacles learner’s faced were explored. Methods – nursing studentswere the participants and online self-reporting method was adopted for the data collection. Self-developedquestionnaire was completed by 138 participants and questionnaire had 36 items to respond on VideoConferencing Platform related to learner’s satisfaction, also opportunities & obstacles encountered whilelearning through VCP.Results – Majority (63%) of the participants were somewhat satisfied, learning through VCP and 26.1% werehighly satisfied. Observation of the opportunities were found to be better learning outcome – brainstormingstimulation, self-motivated learning, able to ask and clear doubts and lecture was reported to be captivating.Another opportunity reported was comfort while learning which included the learning in personal space,no compulsion of physical presence at teaching institute and freedom to choose which lecture to attend.Obstacles reported were related to the classroom environment where the chances avoiding questions andfooling the instructor was reported by majority participants, technical challenges like slow internet disturbedthe lecture and made it difficult to articulate lecture and also missed part of lecture. Other obstacles reportedwere decreased social interaction, participants found learning through VCP to be tiresome as compared totraditional classroom, connectivity issues disturbance create due to the surroundings. Association betweenthe course of study with satisfaction level, opportunities and obstacles were found to be significant, whereasthe association between the time spend on VCP was found to be significant only with obstacles.
Prevalence of the Risk of Obstructive Sleep Apnea in Relation to Obese and Overweight Collegiate Students
Authors: K.Jothi Prasanna  , Shanmuga Vishnu. K
Published: April 2021

INTRODUCTION: Obstructive sleep apnea is described as monotonous collapse and reopening of upperairway during sleep which affect the ventilation. This Obstructive sleep apnea is common among obese andoverweight individuals. OBJECTIVE: The objective of the study was to determine prevalence of the riskof obstructive sleep apnea in relation to obese and overweight collegiate students.METHODOLOGY: It is a non- experimental study with sample size of 100 which include obese andoverweight. 50 subjects with obese and 50 subjects with overweight are included and assessed for risk ofsleep apnea. OUTCOME MEASURES: Berlin Questionnaire RESULTS: Percentage of low risk wasabout 56, whereas the high risk Obstructive sleep apnea was 44% among overweight. Percentage of highrisk was 52 and low risk 48. CONCLUSION: This study concluded that the prevalence of Obstructive sleepapnea had a higher risk among obese when compare to the overweight individuals.
Estimation of Chronological Age from Advanced Glycation End Products Level in Vitreous Fluid
Authors: Kanicnan Intui  , Churdsak Jaikang  , Somlada Watcharakhom  , Yutti Amornlertwatana
Published: April 2021

Background: Chronological age estimation is an important process for corpse identification. Advancedglycation end products (AGEs) are accumulated during lifetime and have been used for forensic identification.The AGEs in vitreous humor still lack of information for age estimation. Objective: To investigate correlationbetween the AGEs level contained in vitreous humor and chronological age in postmortem cases. Methods:The vitreous humor samples were collected from the postmortem cases (n=142). The AGEs levels weredetermined by spectrofluorometer and presented in microgram of quinidine hemisulfate equivalent (?g QE/mL) and nanogram of pentosidine equivalent (ng PE/mL). Stepwise linear regression was used to generatethe equation. Results: The QE and PE showed mild positive correlation (r = 0.350 and 0.195; p <0.001,respectively) while the PE/QE ratio showed moderate negative correlation with age (r = -0.561, p <0.001).The predicted equation showed error value 12 years and gave accurate prediction in range 40-59 years old.Conclusion: The AGEs contained in the vitreous humor correlated with chronological age in postmortemcases. The other fluorescence molecules might be interfere during the AGEs measurement then the specificmethods should be developed for measuring the AGEs level to decrease the error value.
NSAID-Induced Adverse Drug Reaction: Mechanism and Management
Authors: Katherine A.Tjenggal  , Rano K. Sinuraya  , Cherry Rahayu  , Rizky Abdulah
Published: April 2021

Non-steroidal anti-inflammatory drugs (NSAIDs) are drugs to reduce pain or swelling. The use of these drugsin high doses or long-term can cause side effects or hypersensitivity problems, also known as Adverse DrugReaction (ADR). A literature review was carried out using the PubMed database by inserting the keywords‘NSAID’, ‘adverse drug reaction’, and ‘hypersensitivity’. All studies related to NSAIDs and their adversedrug reactions were included in this review, while genetic or pharmacogenomics studies and NSAIDs’effectiveness were excluded. The results showed that gastrointestinal (GI) problems such as duodenal ulcersor erosive gastritis are the most common diclofenac effects (2.05%). Cardiovascular issues, such as acutemyocardial infarction, were mostly caused by rofecoxib (2.12%). Hypersensitivity, both respiratory andskin, is commonly caused by ibuprofen with prevalence 50% and 67%, respectively. The most frequentkidney problem related to NSAIDs use is acute kidney injury. In comparison, the common hypersensitivityproblems are asthma, urticaria, and angioedema. Adverse drug reactions can be prevented or treated bylowering the dose, reducing the duration of treatment, adding companion drugs, or changing the type ofNSAID. In conclusion, it can be seen that ibuprofen severely caused kidney problems and hypersensitivity.On the other hand, diclofenac caused digestive issues, and rofecoxib caused cardiovascular problems.
Potential Stem Cells of Oral Origin- A review on Induced Pluripotent Stem Cell Technology
Authors: Keerthi Narayan. V  , Vasumathi.D  , Pavithra.D  , NirmalFamilaBettie
Published: April 2021

Mesenchymal stem cells are isolated from multiple tissues, such as bone marrow, peripheral blood,umbilical cord blood, adult connective tissue, dental tissues, placenta, and amniotic membrane. Oralderived mesenchymal stem cells (OMSC’s) are multipotent cells, though differentiates into odontoblast,cementoblast, osteoblast, chondrocyte, adipocyte, melanocyte, endothelial cell hepatocyte, myoblast andneural cell but shows limited differentiating into only these specific types of cells or mesenchymal origincells. Induced pluripotent stem cells (iPSC’s) are the potential stem cells induced through reprogrammingsuch somatic cells genetically by presenting with distinct or causative factors. Growth factors and signallingmolecules have the capacity to induce cellular proliferation and cellular differentiation. Addition oftranscription factors to a population of differentiated cells does not promise reprogramming of the potentialstem cells. Furthermore, ethical issues related with the development of embryonic stem cells (ESC’s) do notapply to iPSCs, which offer a non-controversial strategy to create patient-specific stem cell lines. Hence thepresent review article was aimed to briefly describe numerous oral mesenchymal stem cells (OMSC’s) androle of Induced potential pluripotent stem cells (iPSCs) in the regenerative medicine and dentistry with afocus on various iPSCs reprogramming techniques in the current scenario.
Effectiveness of Gyro Based Handglove for Improving Activities of Daily Living among the Individuals Suffering with Hand Tremors
Authors: Vaishnavi S Desai  , S. Anandh
Published: April 2021

Objectives: Tremor patients can face many difficulties and challenges in performing their daily lifeactivities. The impact of tremor on patients’ lives has various dimensions, captured by questionnaires fortremor severity, disability, handicap, and quality of life. Quality of life is substantially decreased mainly formental domains, indicating a major impact of psychosocial aspects. The purpose of this study is to reducehand tremors with the help of gyro based hand glove to improve the activities of daily living of the patient.Methodology: 24 subjects (M:16; F:8) suffering from hand tremors were selected on the basis of inclusioncriteria. Name, age and gender of the individuals participating the research was documented. ADL and IADLscore of all the individuals was calculated both pre application of the glove and post application of glove.The scale used for assessing the score of ADL and IADL was ‘Katz index of independence in activities ofdaily living scale’ and ‘Lawton-Brody instrumental assisted activities of daily living scale’ respectively.Result: From this study we get to know that there is increase in the score of ADL by 17.8%. that there isincrease in the score of ADL by 38.63%.Conclusion: On the basis of the result of the study, it was concluded that subjects suffering with handtremors had significant increase in the score of the activities of daily living as well as the score of theirInstrumental activities of daily living.
Assess the Effectiveness of Planned Teaching on Knowledge Regarding the Ill Effects of Wearing High Heels among Adolescence Girls
Authors: Khushbu Meshram  , Arundhati Borkar  , Sneha Chaudhari  , Suvidha Bhujade  , Akanksha Chavhan  , Tejashri Chandekar
Published: April 2021

Introduction: Fashion is like a circle; after some time it keeps changing and gets to the same position. Highheels are frequently worn by many women and form an important part of female gender identity, with highheels, the center with gravity shifts against a person wearing high heels and the buttocks and spine are outof balance.Long use of High Heels tends to increase buttock size. Aims: Assess the effectiveness of plannedteaching on knowledge regarding the ill effects of wearing high heels among adolescence girls. Materialsand methods : Present study is Pre experimental one group pretest ,post test design was used study has beenconducted among 60 adolescence girls in R.S. Mundle Dharampeth, Arts and Commerce college, Nagpur.Structured questionnaires given to assess the existing knowledge and the planned teaching were given afterthe pre test and assess the post test knowledge to see the effectiveness of planned teaching. Results: Thelevels of knowledge were seen into 4 categories, poor, average, good and excellent of antenatal mothers,frequency and percentage wise distribution of antenatal mothers according to post test level of knowledgeregarding ill effects of wearing high heels. The Mean score of knowledge in post test was 16.10 ± 0.70 andof excellent knowledge score in post-test was 94.70 ± 4.15.Conclusion- Present study identify the existingknowledge of adolescence girls structure teaching It was found that adolescence girls having a good levelof knowledge regarding ill effects of wearing high heels in pre test and which were significantly moreimprovement after attending structured teaching and they have been more gained knowledge about the illeffects of high heels with scientific rationale. So planned teaching was effective in enhancing the knowledgeof ill effects of wearing high heels.
Prevalence of Microscopic Calcium Oxalate crystalluria in Biochemically Normal Urine Samples
Authors: Kuntal Devesh Patel
Published: April 2021

Background: Calcium oxalate is the major cause of human kidney stones in all over the globe. These arecolorless, refractile, and envelope-shaped. Sometimes dumbbell-shaped or peanut-like forms are seen. Theyare soluble in dilute Acids. Consumption of some types of foods like tomatoes, spinach, cabbage, asparagus,etc. causes upsurge in its number. A large number are seen in ethylene glycol poisoning.Method : This present research was aimed at investigating the prevalence of calcium oxalate crystalluria inbiochemically normal urine samples came to Clinical pathology section of Central Diagnostic Laboratory,Dhiraj General Hospital for the period of two months from 1st December 2019 to 31st January 2020. Theurine samples were centrifuged at 3000 rpm for 15 min. The supernatant were decanted and the sedimentswere viewed under microscope using high power objective lens with 40x magnification. Total 400 urinesamples with normal urine protein and normal urine sugar were analyzed microscopically using an Olympusmicroscope 4000x. Results showed that calcium oxalate crystals had the prevalence rate of 13.26 %.Conclusion: The study showed that this much of prevalence of COC was associated with food intake andthe social life style.
Exfoliative Cellular Study of Pathological Body Fluids – 1 year Retrospective Study
Authors: Kuntal Devesh Patel
Published: April 2021

Background: Body fluids are straightforwardly gained by tapping. For fluid routine and microscopicexamination, laboratory receives pleural, peritoneal, CSF, Urine and Synovial fluids. The cytologicalevaluation and biochemical study of these received fluids can be fruitful as assistance to the diagnosis.Present study is an attempt to analyze all the samples referred for cytological evaluation.Method: The study is cross-sectional descriptive, analytical and retrospective kind of study carried out inCentral Laboratory of Dhiraj Hospital, over a period of one year from June2019 to May2020. Fluids suchas peritoneal, pleural, CSF, synovial, etc. were received were examined under light microscope and foundpathologies are classified in malignant and non-malignant entities. A total of 506 body fluids were receivedin the one year period. Majority of the cases were Peritoneal fluid comprised of 242 (47.8 %) followed bypleural fluid with 162 cases (32.0 %). Majority cases were categorized under Non-malignant group. Slightmale dominance was observed with the mean age of 46.2 years.Conclusion: Thorough analysis and appropriate clinical correlation will aid in improving patient treatmentand care. Cytology of the fluid is a rapid and simple diagnostic technique for diagnosis of pathologicalconditions in malignant and non-malignant cases.
Glycated Haemoglobin- Recent Developments and Review on Non-Glycemic Variables
Authors: Lata Kanyal Butola  , Ranjit Ambad  , Deepika Kanyal  , Anjali Vagga
Published: April 2021

Glycated hemoglobin (HbA1c) is the current tool for monitoring glycemic control once a diagnosis ofdiabetes is established. Its role in the diagnosis of diabetes has only recently come to attention. In the past,many international organizations have discussed the role of HbA1c in the diagnosis of diabetes and rejectedthis application as appropriately DCCT-aligned assays were not used or available globally. Consideringthe high biological variability, the dynamics of glucose, as well as the limitations of blood glucosemonitoring technology, at that time, the possibility of obtaining an integrated average glycemia value bythe measurement of a single biomarker elicited immense interest and provided a powerful tool in bothdiabetes research and clinical management. HbA1c testing was soon facilitated by the development of a newanalytical methodology that was suitable for use in clinical laboratories. However, a consensus statement in2007 on assays used to report HbA1c has now further strengthened the case for a change in the diagnosisof diabetes. Using HbA1c as a screening or diagnostic tool has some logistical advantages over traditionalglucose testing (either oral glucose tolerance test [OGTT] or fasting plasma glucose [FPG]). Patients canpresent for a relatively quick test in a non-fasted state at any point of the day, allowing more scope foropportunistic screening. HbA1c assay readings are less prone to recent influences of physical or emotionalstress and provide an indication of longer term glycemic control spanning the last 2–3 months. Owing tosuch logistical advantages there are calls for HbA1c to become the preferred diagnostic tool over glucosetests. Performing the HbA1c test regularly allows the assessment of glycemic control and verification of theefficacy of medication treatment and of education for self-care. It is estimated that 33% to 49% of peoplewith DM2 cannot achieve adequate goals for glucose, blood pressure, or lipid profile control and only 14%reach normal parameters in these measurements.
Role of Omega 3 Fatty acids, Vitamin D, Vitamin B12, Vitamin B6 and Folate in Mental wellbeing- A Short review of Literature
Authors: Lata Kanyal Butola  , Deepika Kanyal  , Ranjit Ambad  , Rakesh Kumar Jha
Published: April 2021

Neuropsychiatric conditions have been linked to around 14 percent of the global disease burden, mainlydue to the chronically debilitating nature of depression and other widespread mental disorders, alcohol anddrug use disorders, and psychosis. The science and lay press have confirmed that vitamin D is an importantfactor that can have major health benefits in the prevention and treatment of many chronic diseases. Mostpeople have inadequate vitamin D levels in this country. This is also relevant for people with depression andother mental illnesses as well. Inadequate food consumption, lifestyle or other factors are a major causes ofVitamin D deficiency. Successful diagnosis and treatment of insufficient levels of vitamin D in people withdepression and other mental illnesses could be a simple and cost-effective therapy that could enhance thelong-term health outcomes and quality of life of patients. It is now well known that omega-3 fatty acids areimportant for physical health, and there is growing evidence that omega-3 fatty acids may also be importantfor mental health. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the two major omega-3fatty acids in fish oil, have essential biological roles within the CNS. DHA is a major structural componentof neuronal membranes, and modifying the neuronal membrane fatty acid composition contributes tofunctional changes in the behaviour of phospholipid membrane-embedded receptors and other proteins.EPA has major physiological roles that can influence the behaviour of neurons. For innumerable aspectsof brain functioning, adequate nutrition is needed. A modifiable risk factor for depression may be the poorquality of diet. The goal was to evaluate and synthesize the existing understanding of the role of nutritionin mental well-being. The risk of depression is increased by low omega-3 fatty acid status. Both fish oil andfolic acid supplements have been successfully used to treat depression. The response to antidepressants isdecreased by folate deficiency. Deficiencies in folate, vitamin B12, Vitamin D, Omega 3 fatty acids, VitaminB6 tend to be more prevalent in depressed individuals than in nondepressed individuals. In this short reviewof Literature we have focused on role of Omega 3 Fatty acids, Vitamin D, Vitamin B12, Vitamin B6 andFolate in Mental wellbeing.
Assessment of Salivary Flow Rate and Carbon Monoxide Level among Smokers, Tobacco Chewers and Control Group
Authors: Manju J  , Krithika C  , Karthikeyan G  , Karishma Chowdary M.V  , Karthika R  , Mugesh Raj S
Published: April 2021

Aim: To assess salivary flow rate and carbon monoxide level among smokers, tobacco chewers and controlgroup.Methodology: The study has total of 45 subjects, which were divided into 3 groups and 15 subjects in each.Group A- smokers’ group, Group B- chewers’ group, Group C-control group. Unstimulated whole salivawas measured by performing modified Schirmer tear strip test(MST). Smokerlyzer used for measuring COlevels from exhaled breath.Result: On analysing the data of SFR between smokers, chewer’s and control group, there was statisticallysignificant result at p value of 0.05 between all groups. On evaluating the co level in smoking group 53.3%presented with higher CO level and 60% chewers presented with lower CO level. In control group 100%were under no risk.Conclusion: The salivary flow rate is reduced in tobacco users in either form. Since smoking group is athigher risk monitoring of carbon monoxide level can be used as the important tool in motivating the tobaccousers to quit the habit.Aim: To assess salivary flow rate and carbon monoxide level among smokers, tobacco chewers and controlgroup.
Assessment of Knowledge, Attitude and Practice of Forensic Odontology among Undergraduate Dental Students
Authors: Manju J  , Krithika C  , Anusha S  , Arputha Madhalan C  , Anu Priya B  , Swathi R
Published: April 2021

Aim: The aim of the study is to assess the level of knowledge, awareness and practice of forensic odontologyamong undergraduate dental students.Methodology: The data was collected through a questionnaire which contained 15 close-ended questionsshared through online platform. And circulated amongst undergraduate dental students through onlineplatform, all data were completely filled and statistical analysis was done.Result: The results of this study show that Interns were the group with the most Knowledge about ForensicOdontology (p=0.0004). 75% of the Interns scored >90 and contrastingly, around 30% of the IV, III, II andI years scored >90.Conclusion: This study divulges that there was adequate knowledge and awareness of forensic odontologyamongst the Interns and very few of other group students (I, II, III and IVyear) have adequate knowledgeand awareness regarding forensic odontology. Although the significance of maintenance of dental recordsare established, it has not been practiced among the students
The Effect Allium sativum (Garlic Extract) as Prebiotic Substance on the Activity of Probiotic Bacteria Lactobacillus acidophilus Against Some Locally Isolates of Pathogenic Bacteria
Authors: Marwa A. Kubba  , Sahar M. Hussein  , Omar S. Al-Zaidi
Published: April 2021

The aim of this study was to improve the growth and inhibitory activity of the selected Lactobacillus isolate.A total of twenty samples of dairy products (fresh yogurt) were collected. Seven isolates of Lactobacillusspecies . were obtained, and identified as three Lactobacillus fermentum, three Lactobacillus acidophilus andone of Lactobacillus brevis. The growth of lactobacillus acidophilus was counted , also inhibitory activity ofLactobacillus acidophilus against some pathogenic bacteria was tested) for two different incubation periodsbefore the addition of Allium sativum(garlic extract) as prebiotic substances. three different concentrationsof it were used by addition of it toDe Man, Rogosa and Sharpe agar (MRS) medium as prebiotic substances , and two incubation periods(24, 48) hour. The effect of Allium sativum on the growth of probiotic bacteria was evaluated, measurementof Lactobacillus acidophilus growth curve was done after and before adding garlic extract. For analyzinginhibitory activity of Lactobacillus acidophilus with the Allium ,results showed that Lactobacillus acidophiluspropagated in MRS fortified with 20% and 30% v/v garlic extract with incubation period 24 hr by giving thehighest inhibition zone.It was concluded that Lactobacillus.acidophilus isolate can grow well and exhibit good effect against Gramnegative bacteria in a medium containing garlic extract (that is added as a substrate supporting probioticgrowth and activity). also it was clear that filtrate of Lactobacillus .acidophilus isolate that propagatingin spesific broth fortified with 20% garlic extract at 48 hr incubation period produce antibacterial effectbetter than 10% , it was concluded that prebiotic treatment enhance the growth of Lactobacillus acidophilusespecially at 24 hr. this may due to fructooligosaccharide content in garlic , also when propagated in MRSwithout prebiotic treatment, and which may due to highly decrease in pH which cause inhibition the growthof Lactobacillus acidophillus.