bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN MODEL PEMBELAJARAN JIGSAW UNTUK MENINGKATKAN HASIL BELAJAR MATEMATIKA SISWA KELAS VII SMPN 1 KARANGPLOSO
Authors: Amargawati Dwi Ambar
Published: March 2018

This study aims to determine the increase of mathematics learning outcomes through the implementation of jigsaw learning model in class VII. The design of this study was classroom action research conducted in two cycles. Results of the study showed student learning activities in the cycles increased by 13.46%, teacher activity 7.36%, and students’ learning outomes up to 95%. Minimum mastery was accomplished by 30 (95%) students and only 2 students that reached below minimum mastery, and average score 78,45.
DEVELOPING ENGLISH MATERIALS FOR CHARACTER BUILDING BASED ON 2013 CURRICULUM FOR EIGHTH GRADE STUDENTS
Authors: Hasanah Imroatul
Published: March 2018

This research developed English Instructional materials for character building based on 2013 Curriculum. The research was carried out in a class of 8th graders of SMP Darul Falah Blitar.  The 23 students were involved in this research in the phase of obtaining information, needs analysis and trying out. The result of needs analysis became the basis of how the researcher composed the English instructional materials with Scientific Approach, official approach of 2013 Curriculum. In the product, an English textbook, the four skills are balance improved; listening, speaking, reading and writing. All of the materials are appropriate with 2013 Curriculum and the contents refer to students’ character building. The materials are for a year of 8th grade which are packaged into seven units. All the steps of learning and exercises in the materials are based on Scientific Approach which has five steps: observing, associating, experimenting, associating and communicating.
APPLICATION OF COLLABORATIVE PROBLEM-BASED LEARNING TO IMPROVE THE QUALITY OF TEACHING AND LEARNING ON APPLIED LINGUISTICS
Authors: Sujito Sujito , Mauttagien Wildan Mahir
Published: March 2018

This study presents teaching process in applied linguistics course using Collaborative Problem-Based Learning (CPBL). The objectives are to see how CPBL increases: (1) students’ active involvement in classroom activities, (2) lecturer-students and students-students communicative interaction, (3) students’ creativity in finishing projects, (4) students’ cognitive comprehension, and (5) level of students’ satisfaction/ positive response to the implementation of CPBL. This study used a two cycle Classroom Action Research using descriptive approach. The subjects were 3 classes with 30 students each Applied Linguistic Course of English Department of IAIN Surakarta. This study revealed that students’ motivation, communicative interaction, students’ creativity in finishing projects, cognitive comprehension and students’ satisfaction/ positive response to the implementation of problem based learning in Applied Linguistics course attained  significant improvement.
VERBAL AND NON-VERBAL EXPRESSIONS IN THE TRADITION OF MOMBOLASUAKO OF TOLAKI
Authors: Pehala Ilfan Askul , Fernandez Inyo Yos , Abdullah Wakit
Published: March 2018

This research aims to classify, describe and explain verbal and non-verbal expressions in eloping tradition (mombolasuako) of Tolaki based on the procession comprehensively. Theories used to solve the problem are ethnolinguistics and ethnoscience. Methodologically, the ethnographic method was used in this study. The data includes primary and secondary data that were collected by participant observation and an in-dept interview. All collected data were analyzed by using Spradely ethnoscience’s analysis and linguistics’ analysis. The study revealed that verbal expressions in mombolasuako include verbal utterances, recitation and remark. The non-verbal expressions consisted of (1) the tradition objects must be served by bride groom consists of process (2) gestures of tradition casts in the implementation of the traditions process and (3) tradition casts. The mombolasuako’s process of verbal and non-verbal expressions including verbal utterances, gestures and tradition casts were adapted to tradition.
STRATEGIES TO DEVELOP ARGUMENTS IN ACADEMIC WRITING BY STUDENTS OF GRADUATE PROGRAM IN INDONESIAN LANGUAGE EDUCATION SEBELAS MARETUNIVERSITY
Authors: Mahsa Masithah , Setiawan Budhi , Rohmadi Muhammad
Published: March 2018

There is a relationship between pattern of arguments in an academic writing and obstacles faced in writing process. This study aims to figure out the strategies to develop arguments in writing a scientific article used by the students of Graduate Program in Indonesia Language Education Sebelas Maret University. The study focuses on obstacles in writing the scientific article, and the strategies how students overcome the problem. This study is a qualitative descriptive research. The instruments were documents and interview sheet that was delivered to the author of the article. In collecting the data, the researcher used purposive sampling technique. The researcher used interactive analysis technique in order to analys the content of the data. Findings of this study showed that there were two obstacles and solution in arranging the arguments, they were internal and external aspect.
USING PROTOCOLS TO IMPROVE GRAMMATICAL ERRORS IN PARAGRAPH WRITING BY THE SEVENTH GRADERS OF SMPN 1 KARANGPLOSO
Authors: Eliyawati Rike
Published: March 2018

Errors in auxiliary verbs have been the common problems faced by Indonesian learners to write in English. The aims of this study are to see   (1)  kinds of errors are identified in the modal auxiliaries the students perform, and (2) how errors are used to improve grammatical sentences in the paragraph.  This study used classroom action research with two cycles.  This study was done involving 32 students of class VII-A of SMPN 1 Karangploso Malang.  The results show that in cycle 1, all aspects of auxiliary verbs including: to be, to do, to have, and modal were made in the error forms.  In average 81.2% students made errors.  In cycle 2, the errors decline into 25%.  In essence 75% of paragraph developed by students after learning protocols to correct the errors have limited errors in the auxiliary verbs.
AFFIXES IN SONG LYRICS OF ADELE
Authors: Yastanti Unpris , Warlina Widya
Published: March 2018

The purpose of this study is to identify Affixes on songs lyric of Adele in her latest albums “25”. Descriptive qualitative is used as the method of the analysis. The research data in this analysis was taken from Song Lyrics of Adele in her latest albums “25”. The result of this research are; (1). There are 22 words Suffixes and two words Prefix (2). There are seven adjective, nine plural, five nouns, two verbs, and one preposition.
PENGEMBANGAN MODUL MEMBACA DAN MENULIS BERBASIS UJI DIAGNOSTIK UNTUK MENINGKATKAN PEMAHAMAN SISWA SMP TERHADAP MATERI POKOK BAHASA INDONESIA
Authors: Suhartono Suhartono , Parmin J. , Wibowo Yermia Nugroho Agung
Published: March 2018

The objective of this study is to devise a Diagnostic-Test-Based of Reading and Writing Module of Bahasa Indonesia for SMP students. The study fcuses on the instructional design of the core materials of Bahasa Indonesia in the School-Based Curriculum. The study uses Research and Development design implementing three circles of activity: planning, designing and development.  Research subjects included 27 ninth gragers of SMPN 28 Surabaya. The study reveals that in the planning stage, core materials of reading and writing were selected by the schools and be listed as Table of Specification before National Leaving Exam. Analysis of diagnostic test indicated that core materials of reading and writing for Bahasa Indonesia deviated problems students faced so that students received no benefits.  The development of the module empirically proved that Diagnostic Test-Based Reading and Writing module increased students accomplishment up to 23.03%.
CHARACTERIZATION IN THE NOVEL ENTITLED SONS AND LOVERS BY DH LAWRENCE
Authors: Muhiddin La
Published: March 2018

This study is qualitative designed to analyze the character of the novel through psychological approach.  The subject of the study is the works of D.H. Lawrence, focusing on the novel "Sons and Lovers". Two kinds of corpuses for analysis were literary elements corpuses, plot, theme, setting and atmosphere, point of view and the main characters corpuses of Gertrude Morel, Walter Morel, William Morel & Miriam Leiver. Data were collected from literary research and library research. The study revealed that the main characters of sons and lovers are round ones. Miriam was said to be very religious, yet she had sexual intercourse before her marriage. It is shown that there are some aspects of moral quality. Educational value appeared in nuance that  revenge does not give us satisfaction. Through out the novel, relevant implication appeared that sexual desire does not belong to love. Sex is also physiological needs and sometimes an expression of love. The self‑actualization need is dominant in Paul.
ERRORS IN THE CLASSROOM: DILEMMAS AND PRACTICES
Authors: Marpinjun Taslimah Retno
Published: March 2018

Human learning is fundamentally a process that involves the making of errors. But the issue of error and how errors are treated in the classroom is still dilemma for many teachers.  One learning approach stated that error correction was avoided, because it makes learners shut off their attempts at communication. However, other learning approaches stated that correction was highly valued, to increase students’ motivation in learning. For the best decision, teacher can use  five key questions dealing with errors’ treatment: (1) should learners’  errors be corrected ?; (2) when should learners’ errors be corrected?; (3) which errors should be corrected?; (4) how should learners’ errors be corrected; and (5) who should do the correcting?
KUALITAS BUTIR SOAL UAS BAHASA INGGRIS UNTUK SISWA MTs DI SAMARINDA
Authors: Sumaningsih Sumaningsih
Published: March 2018

This study is aimed at seeing the item quality of English test used for Leaving Exam at SMP Samarinda.  Analysis is used to see item difficulty (p), discrimination (D), distracter effectiveness, validity, and reliability. The results of analysis show that of 45 items, 19 (42.2%) must be dropped due to the poor p and 17 (37.8%) receive the low D.  Analysis of p and D reveal that of 45 items, only 5 (11.1%) items are applicable, 21 (46.7%) need revision, and 19 (42.2%) should be dropped.  The distracters are also poor, as 25 (55.6%) items have very poor distracters.  Validity testing under Product Moment formula achieved low value (0.346) and reliability testing under KR-21 shows fair value (0.650).
MODEL BERMAIN SULAP DALAM PEMBELAJARAN MENULIS BERITA KELAS VIII SMP
Authors: Hanggoro Wahyu Puji
Published: March 2018

The objective of this paper is to describe how teaching to write news using creative and innovative techniques.  The model is BERMAIN SULAP an acronym of Cover the News, Use recording tools, Recall evidences in the sites, Organize, and Report.  The product being described in this paper is an instructional model explaining how writing news is developed for teaching for the grade VIII SMP students and steps to teach news using Bermain Sulat techniques.  This model is designed based upon instructional objective in the School Based Curriculum 2006 (KTSP) incurring benefuts and weaknesses of the model.
PENINGKATAN KEMAMPUAN MENULIS PUISI DENGAN TEKNIK KATA MENGALIR BERBANTUAN MEDIA BENDA KONKRET PADA SISWA KELAS VIII SMPN 5 PAGENTAN
Authors: Romelah Romelah
Published: March 2018

The aim of this study is to improve the ability to write poetry with the technique of flow-assisted media said concrete objects. This study uses a classroom action research. The process of the implementation of this action research refers to the spiral model Kemmis and Tagart with four steps include research, planning, implementation, observation, and reflection consisting of two cycles. Results of the research cycle I the average value of 69.70 students with classical completeness 50%. Results of the second cycle the average value of 78.86 with 95.45% classical completeness. These results are supported by the results of the questionnaire statement of the student's interest first cycle of 81.81% increased in the second cycle to 100%. Based on the above results it can be concluded that the use of media-assisted techniques flowing said concrete objects can improve the quality of the processes and outcomes of learning to write poetry.
REALITAS BAHASA DALAM POSTULAT SAPIR DAN WHORF
Authors: Yunhadi Wuwuh
Published: March 2018

In the field of linguistics, Sapir and Whorf claimed that language and culture are closely related.  Language is the reflection of how culture of a community shares.  Sapir and Whorf defined two main functions of language in the community.  First, language will change from the original if the language is used far from the center where the language origins.  This concept is named as language drift.  Second, the characteristics of individuals’ culture are manifested in the language they use. This paper is a brief review on theories of language from Sapir-Whorf that inspires on the development of sociolinguistics and discourse analysis in the era that follows.
KAJIAN STILISTIKA PADA TAJUK RENCANA SURAT KABAR HARIAN UMUM HALUAN
Authors: Syah Nur Aini
Published: March 2018

This qualitative study analyzes style used in the Haluan newspaper, emphasizing the language used in its editorials.  The language styles were focused on the word choice, figurative language, imagery, and the role of the style.  The data in this study were a lingual unit in the form of words, phrases, or clauses. The data sources was Editorial posted on June 6th, 2016. The results of this study showed that the use of connotative, general, special senses, and a scientific word was prominent. The figurative language, such as climax, anti-climax, repetition, redundancy, enumeration, ellipsis, polidenton, paradoxically, correction, and personification was dominant. The images contained in this Editorial included visual, motion and auditory imageries. Spiritual and social values play a role in the Haluan Daily News Editorial.
ETIKA PENGEMBARAAN ILMU MASYARAKAT JAWA PADA NASKAH SERAT DEWA RUCI KARYA R. Ng. YASADIPURA I DALAM PERSPEKTIF KEHIDUPAN MODERN
Authors: Suprayitno Edy
Published: March 2018

This research examines the etiques in acquiring knowledge in the Javanese community tradition. The object of this study was Dewa Ruci script by R.Ng. Yasadipura I. The research used qualitative descriptive approach and content analysis as the research design assigning the sociology theory for literature. The finding showed an evidence when acquiring the knowledge, the Javanese always taught four aspects of heritages to their descendants that is inherently asserted in the perspective of the Javanese community and their philosophy. Those aspects attached within the spirit of the Javanese consisted of: (a) enthusiasm, (b) do not give up easily, (c) persistence, and (d) students’ obedience.
HUBUNGAN ANTARA DUKUNGAN SUAMI DENGAN KECEMASAN SELAMA PERSALINAN PADA PRIMIGRAVIDA DI PUSKESMAS MLATI II SLEMAN
Authors: Retnowati Retnowati , Mawarti Retno , Yati Dwi
Published: March 2018

Background: Labor is the process of delivering a baby that occurs in full-term pregnancy (37-42 weeks). One of the efforts to reduce anxiety during labor is to provide support from a significant person, a husband. Husban’s support in labor process is a source of strength for woman who cannot be replaced by health personnel.

Objective: To identify the relationship between husband’s support and anxiety level during labor on primigravida at Mlati II Health Center Sleman.

Methods: This study was descriptive quantitative, with cross sectional approach. The samples were 20 respondents who were selected withaccidental sampling technique. Research employed questionnairesto measure husband’s support and mother’s anxiety level. Study used univariable and bivariable analysis.

Result: Most of the husband's support during labor on primigravida at Mlati II Health Center Sleman were at high category (75.0%). The majority of mothers experienced mild anxiety (50.0%). The relationship between husband’s support and anxiety during childbirth in primigravida mother at Mlati II Health Center Sleman district was at strong category; r = -0.632 (.600 to .799).

Conclusion : There was a relationship between husbands’ support andprimigravida mothers’ anxiety level during labor at Mlati II Health Center Sleman.
STUDI DESKRIPTIF PERSIAPAN DOKUMEN AKREDITASI PUSKESMAS 2015 TENTANG PEMBAKUAN KODE DI PUSKESMAS NANGGULAN KULON PROGO
Authors: Nur Faiza Ida Ayu , Miharti Rawi
Published: March 2018

Background: In the era of the ASEAN Free Trade Area (AFTA), the quality of health services is required to compete internationally. The data of diagnostic and procedure is one of the determinants of service quality. One of the ways to improve the quality of health services is to carry out accreditation. Puskesmas Nanggulan Kulon Progo prepared the documents about standardisation of code for Puskesmas Accreditation 2015. Furthermore, in National Health Insurance program (Jaminan Kesehatan Nasionalprogram) diagnostic and procedure codes are used as the terms to claim to Badan Penyelenggara Jaminan Sosial (BPJS).

Objective: This research aimed to explore the documents preparation of Puskesmas Accreditation 2015 regarding code standardisation at Puskesmas Nanggulan Kulon Progo.

Method: This research was a descriptive research with a qualitative approach. The design of the research used in this study was phenomenology. Data collection technique in this study was observation towards the documents of accreditation related to codestandardisation and interview withfive respondents who involvedin the accreditation team.

Results: The documents preparation forPuskesmas Accreditation 2015 regardingcodestandardisation was successfully completed. The preparation for accreditation related to code standardisation were as follow:

Man: planing the finance scheme,prepare documents related to accreditation, form a team of accreditation documents arrangement

Method: process of forming a team that will arrange the documents and the process of preparing the documents

Materials: preparing stationery for office use

Machines: preparing laptop (or computers) and printer

Money : meeting all the financial needs.

Conclusion:Documents preparation towards Puskesmas accreditation require human resource, methods, materials, machines, and fund.

Keywords: Accreditation, accreditation preparation, puskesmas accreditation, 5M, standardisation of the

code.
PENERAPAN HEALTH BELIEF MODEL SEBAGAI UPAYA PENCEGAHAN INFEKSI MENULAR SEKSUAL PADA IBU RUMAH TANGGA
Authors: Agustina Silvia Ari , Murti Bhisma , Demartoto Argyo
Published: March 2018

Latar Belakang. Masalah kesehatan seksual dan reproduksi semakin menjadi perhatian di seluruh dunia antara lain berkaitan dengan kebersihan genetalia. Perawatan genital masih sangat tabu untuk dibicarakan dikalangan masyarakat Indonesia. Higiene Genital yang buruk dapat meningkatkan risiko mengalami IMS. Persepsi dalam Health Belief Model (HBM) diyakini dapat menentukan kemungkinan individu melakukan perilaku kesehatan.

Objective: Penelitian ini untuk menganalisis penerapan Health Belief Model dengan higiene genital Ibu Rumah Tangga

Metode. Objek penelitian  ini adalah Ibu Rumah Tangga, dengan total sampel 101, termasuk 2 Ibu Rumah Tangga, 2 Suami, petugas Puskesmas yang melayani penapisan Infeksi Menular Seksual dan 1 Lembaga Swadaya Masyarakat. Teknik sampling menggunakan quota sampling. Jenis penelitian ini mixed methodology dengan strategi eksplanatoris sekuensial dan menggunakan pendekatan cross sectional study.Teknik pengambilan data kuantitatif dengan menggunaan kuesioner tertutup dan untuk data kualitatif dengan wawancara mendalam. Analisis yang digunakan adalah regresi linier ganda. Validitas dan reliabilitas data kualitatif menggunakan triangulasi sumber dan metode.

Hasil: Higiene Genital dengan beberapa variabel independen yang diteliti mempunyai hubungan yang positif dengan persepsi kerentanan (b:0,97; CI 95%: 0,87 hingga 1,06; p<0,01), efikasi diri (b: 0,02; CI 95%: 0,00 hingga 0,05; p<0,05), dan cues to action higiene genital (b:0,16; CI 95%: 0,08 hingga 0,23; p<0,01). Terdapat hubungan negatif antara higiene genital dengan persepsi hambatan higiene (b:-0,13; CI 95%: -0,18 hingga -0,09; p<0,01). Secara bersama-sama seluruh variabel independen di dalam model regresi linier ganda ini mampu menjelaskan higiene genital sebesar 84,5%. Ibu Rumah Tangga menyatakan bahwa higiene genital penting, tetapi dalam menjaga kesehatan alat kelaminnya masih kurang tepat, yaitu seperti sering menggunakan pembersih kewanitaan, celana dalam yang ketat, dan saat keputihan sering menggunakan pentyliner.

Kesimpulan. Terdapat 4 komponen Health Belief Model berhubungan dengan higiene genital.
HUBUNGAN POLA ASUH DENGAN POLA PERKEMBANGAN SEKSUAL SEKUNDER PADA SISWA SMP
Authors: Mayang Sari Uci , Musvita Ayu Suci
Published: March 2018

Background: Adolescence is a transition period from childhood to adulthood, both physically and psychologically. Parents are generally considered as primary teachers for their children, therefore parents play important roles in children development. Parenting style is one of the factors associated with the pattern of secondary sexual development.

Objective: This study aimed to examine the relationship between parenting style and the pattern of secondary sexual development in junior high school students.

Methods: This research was an observational analytic study, using cross sectional approach. The study population was all male students at SMP 1 Berbah Yogyakarta (188 students). Samples were selected using purposive sampling, involving 143 respondents. Data were analyzed with Chi square test.

Result: There was a correlation between parenting style and the pattern of secondary sexual development (p= 0.000 <0.05),  with PR value of 4,975, CI 95 % of 1,831-13,516.

Conclusion: There was a relationship between parenting style and the pattern of secondary sexual development in junior high school students.

Keywords: Adolescence, Parenting, Patterns of Sexual Secondary Students
GAMBARAN KARAKTERISTIK WANITA YANG MENGALAMI KANKER SERVIKS DI RUMAH SAKIT UMUM DAERAH (RSUD) PANEMBAHAN SENOPATI BANTUL YOGYAKARTA
Authors: Anggraeni Fatimah Dewi , Rahayu Retno
Published: March 2018

Background : Cervical cancer is still becoming the most prevalent diseases in Indonesia. Health Department of Indonesia in 2012 recorded that the predicted incidence and mortality rate which caused by cervical cancer were 13.2 million of lifes. Factors that affecting cervical cancer are age, education, job, parity, and hormonal contracepcy. This statement is supported by the Hospital Information System (HIS) data in the year of 2013 which showed that there were 130 cases of cervical cancer in Yogyakarta (DIY). The opreliminary study obtained that in 2015 there were 50 persons of cervical cancer sufferer in Panembahan Senopati Public Hospital, which were consist of 40 outpatient cases and 10 inpatient cases.

Aim : This study aimed to know the characteristics of mothers who encounter cervical cancer.

Research Methods : This research was a descriptive quantitative research. The sampling technique used in this research was total sampling technique. The samples were 50 respondents with frequency distribution that obtained by using secondary data and checklist methods.

Results : Most of mothers who encounter cervical cancer in Panembahan Senopati public hospital Bantul Yogyakarta that aged >35 years old were as many as 34 respondents (68.0%), as many as 26 respondents (52.0%) were high school educated or graduated, as many as 18 repondents (36.05) were statused as a farmer, as many as 18 repondents (36.0%) were primiparas and grandemulti parity, and as many as 29 respondents (58.0%) were using hormonal contracepcy.

Conclusion : Mothers who encounter cervical cancer in Panembahan Senopati public hospital Bantul Yogyakarta that aged >35 years old were: high school educated or graduated, farmers, primiparas and grandmultiparas, and using hormonal contracepcy.

Keywords : Characteristic, Cervical cancer
A PERILAKU MENCUCI TANGAN PENGUNJUNG RUMAH SAKIT DI RUMAH SAKIT SWASTA YOGYAKARTA
Authors: Theresia Siwi Ikaristi Maria
Published: March 2018

Background:  Visitors take part in the occurrence of nosocomial infections. Their hands are a reservoir for microorganisms that can be transmitted to patients as individuals susceptible for secondary infections. Hand washing before and after visiting patients is the easiest way to remove colonies of microorganisms in the hands. The alcohol-based hand rub is available for visitors in the hospital’s rooms but there are no evaluation by hospital managemen.    

Objective: This study aims to evaluate hand-washing behavior of visitors at a private hospital in Yogyakarta.

Methods: Research method used descriptive quantitative survey. Sample was taken by accidental sampling from 2015 - 2017 and got 229 respondents. Data collection by observation in the room includes ICU, ICCU, surgical ward and post partum ward.

Results: The result showed that percentage visitors who did not wash their hands before and after entering in the ICU was  50% and 83.33%, in the medical ward was 80% and 81.82%, in the ICCU was 81,73% and 70,19% and in the post partum ward was 57,5% and 30%.

Conclusion: The high percentage of respondents who did not wash their hands before and after visiting patients is an important concern because they will carry microorganisms that can be transmitted to others. Suggestions for hospital are to campaign, make banners and leaflets for health promotion of the importance washing hands before and after visiting patients in the hospital for public.

Key words: hand washing, visitors, nosocomial infection.
Four Weekly Ayahuasca Sessions Lead to Increases in “Acceptance” Capacities: A Comparison Study With a Standard 8-Week Mindfulness Training Program
Authors: Soler Joaquim , Elices Matilde , Dominguez-Clavé Elisabeth , Pascual Juan C. , Feilding Amanda , Navarro-Gil Mayte , García-Campayo Javier , Riba Jordi
Published: March 2018

Background: The therapeutic effects of the Amazonian plant tea ayahuasca may relate to its ability to enhance mindfulness capacities. Ayahuasca induces a modified state of awareness through the combined action of its active principles: the psychedelic N,N-dimethyltryptamine (DMT) and a series of centrally acting β-carbolines, mainly harmine and tetrahydroharmine. To better understand the therapeutic potential of ayahuasca, here we compared the impact on mindfulness capacities induced by two independent interventions: (a) participation in four ayahuasca sessions without any specific purpose related to improving mindfulness capacities; and (b) participation in a standard mindfulness training course: 8 weeks mindfulness-based stress reduction (MBSR), with the specific goal of improving these skills.

Methods: Participants of two independent groups completed two self-report instruments: The Five Facet Mindfulness Questionnaire (FFMQ) and the Experiences Questionnaire (EQ). The MINDSENS Composite Index was also calculated, including those EQ and FFMQ items that have proven to be the most sensitive to meditation practice. Group A (n = 10) was assessed before and after the last of four closely spaced consecutive ayahuasca sessions. Group B (n = 10) was assessed before and after completion of a standard 8-week MBSR course.

Results: MBSR training led to greater increases in overall mindfulness scores after the 8-week period. MBSR but not ayahuasca led to increases in the MINDSENS Composite Index. However, the ayahuasca sessions induced comparable increases in the Non-Judging subscale of the FFMQ, specifically measuring “acceptance.” Improving this capacity allows for a more detached and less judgmental stance toward potentially distressing thoughts and emotions.

Results: The present findings suggest that a small number of ayahuasca sessions can be as effective at improving acceptance as more lengthy and costly interventions. Future studies should address the benefits of combining ayahuasca administration with mindfulness-based interventions. This will allow us to investigate if ayahuasca will improve the outcome of psychotherapeutic interventions.
Evaluation of Different Gases and Gas Combinations for On-Farm Euthanasia of Pre-Weaned Pigs
Authors: Kells Nikki , Beausoleil Ngaio , Johnson Craig , Sutherland Mhairi
Published: March 2018

The aim of this research was to evaluate the welfare of pre-weaned piglets euthanised using three different gas treatments: 100% carbon dioxide (CO2), 100% argon (Ar) or a mixture of 60% Ar/40% carbon dioxide (Ar/CO2). Two studies (n = 5 piglets/treatment/study) were conducted: (1) behavioural and physiological data were collected from conscious piglets during exposure to test gases via immersion in a pre-filled chamber and (2) electrophysiological data were collected from lightly anaesthetised, intubated and mechanically ventilated piglets exposed to the same test gases. Based on the duration of escape attempts and laboured breathing, piglets exposed to 100% CO2 experienced more stress than piglets exposed to 100% Ar prior to loss of consciousness, but there appeared to be no advantage of mixing Ar with CO2 on indices of animal welfare. However, spectral analysis of the electroencephalogram revealed no changes consistent with nociception during exposure to any of the three gas treatments. Based on the behavioural response to gas exposure, all gases tested caused signs of stress prior to piglets losing consciousness and hence alternative methods of euthanasia need to be evaluated.
A Kernel Least Mean Square Algorithm Based on Randomized Feature Networks
Authors: Liu Yuqi , Sun Chao , Jiang Shouda
Published: March 2018

To construct an online kernel adaptive filter in a non-stationary environment, we propose a randomized feature networks-based kernel least mean square (KLMS-RFN) algorithm. In contrast to the Gaussian kernel, which implicitly maps the input to an infinite dimensional space in theory, the randomized feature mapping transform inputs samples into a relatively low-dimensional feature space, where the transformed samples are approximately equivalent to those in the feature space using a shift-invariant kernel. The mean square convergence process of the proposed algorithm is investigated under the uniform convergence analysis method of a nonlinear adaptive filter. The computational complexity is also evaluated. In Lorenz time series prediction and nonstationary channel equalization scenarios, the simulation results demonstrate the effectiveness of the proposed algorithm.
Polyphonic Piano Transcription with a Note-Based Music Language Model
Authors: Wang Qi , Zhou Ruohua , Yan Yonghong
Published: March 2018

This paper proposes a note-based music language model (MLM) for improving note-level polyphonic piano transcription. The MLM is based on the recurrent structure, which could model the temporal correlations between notes in music sequences. To combine the outputs of the note-based MLM and acoustic model directly, an integrated architecture is adopted in this paper. We also propose an inference algorithm, in which the note-based MLM is used to predict notes at the blank onsets in the thresholding transcription results. The experimental results show that the proposed inference algorithm improves the performance of note-level transcription. We also observe that the combination of the restricted Boltzmann machine (RBM) and recurrent structure outperforms a single recurrent neural network (RNN) or long short-term memory network (LSTM) in modeling the high-dimensional note sequences. Among all the MLMs, LSTM-RBM helps the system yield the best results on all evaluation metrics regardless of the performance of acoustic models.
New Surrogate Model for Wind Pressure Coefficients in a Schematic Urban Environment with a Regular Pattern
Authors: Nguyen Van Tam , De Troyer Frank
Published: March 2018

Natural ventilation and the use of fans are recognized as sustainable design strategies to reduce energy use while reaching thermal comfort. A big challenge for designers is to predict ventilation rates of buildings in dense urban areas. One significant factor for calculating the ventilation rate is the wind pressure coefficient (Cp). Cp values can be obtained at a high cost, via real measurements, wind tunnel experiments, or high computational effort via computational fluid dynamic (CFD) simulation. A fast surrogate model to predict Cp for a schematic urban environment is required for the integration in building performance simulations. There are well-known surrogate models for Cp. The average surface pressure coefficient model integrated in EnergyPlus considers only a box-shaped building, without surrounding buildings. CpCalc, a surrogate model for Cp, considers only one height of neighbouring buildings. The Toegepast Natuurwetenschappelijk Onderzoek (TNO) Cp Generator model was available via web interface, and could include several box-shaped buildings in the surrounding area. These models are complex for fast integration in a natural ventilation simulation. For optimization processes, with thousands of simulation runs, speed is even more essential. Our study proposes a new surrogate model for Cp estimation based on data obtained from the TNO CP Generator model. The new model considers the effect of different neighbouring buildings in a simplified urban configuration, with an orthogonal street pattern, box-shaped buildings, and repetitive dimensions. The developed surrogate model is fast, and can easily be integrated in a dynamic energy simulation tool like EnergyPlus for optimization of natural ventilation in the urban areas.
Process Analytical Technology for Advanced Process Control in Biologics Manufacturing with the Aid of Macroscopic Kinetic Modeling
Authors: Kornecki Martin , Strube Jochen
Published: March 2018

Productivity improvements of mammalian cell culture in the production of recombinant proteins have been made by optimizing cell lines, media, and process operation. This led to enhanced titers and process robustness without increasing the cost of the upstream processing (USP); however, a downstream bottleneck remains. In terms of process control improvement, the process analytical technology (PAT) initiative, initiated by the American Food and Drug Administration (FDA), aims to measure, analyze, monitor, and ultimately control all important attributes of a bioprocess. Especially, spectroscopic methods such as Raman or near-infrared spectroscopy enable one to meet these analytical requirements, preferably in-situ. In combination with chemometric techniques like partial least square (PLS) or principal component analysis (PCA), it is possible to generate soft sensors, which estimate process variables based on process and measurement models for the enhanced control of bioprocesses. Macroscopic kinetic models can be used to simulate cell metabolism. These models are able to enhance the process understanding by predicting the dynamic of cells during cultivation. In this article, in-situ turbidity (transmission, 880 nm) and ex-situ Raman spectroscopy (785 nm) measurements are combined with an offline macroscopic Monod kinetic model in order to predict substrate concentrations. Experimental data of Chinese hamster ovary cultivations in bioreactors show a sufficiently linear correlation (R2 ≥ 0.97) between turbidity and total cell concentration. PLS regression of Raman spectra generates a prediction model, which was validated via offline viable cell concentration measurement (RMSE ≤ 13.82, R2 ≥ 0.92). Based on these measurements, the macroscopic Monod model can be used to determine different process attributes, e.g., glucose concentration. In consequence, it is possible to approximately calculate (R2 ≥ 0.96) glucose concentration based on online cell concentration measurements using turbidity or Raman spectroscopy. Future approaches will use these online substrate concentration measurements with turbidity and Raman measurements, in combination with the kinetic model, in order to control the bioprocess in terms of feeding strategies, by employing an open platform communication (OPC) network—either in fed-batch or perfusion mode, integrated into a continuous operation of upstream and downstream.
Hallucinogen Persisting Perception Disorder: Etiology, Clinical Features, and Therapeutic Perspectives
Authors: Martinotti Giovanni , Santacroce Rita , Pettorruso Mauro , Montemitro Chiara , Spano Maria , Lorusso Marco , Di Giannantonio Massimo , Lerner Arturo
Published: March 2018

Hallucinogen Persisting Perception Disorder (HPPD) is a rare, and therefore, poorly understood condition linked to hallucinogenic drugs consumption. The prevalence of this disorder is low; the condition is more often diagnosed in individuals with a history of previous psychological issues or substance misuse, but it can arise in anyone, even after a single exposure to triggering drugs. The aims of the present study are to review all the original studies about HPPD in order to evaluate the following: (1) the possible suggested etiologies; (2) the possible hallucinogens involved in HPPD induction; (3) the clinical features of both HPPD I and II; (4) the possible psychiatric comorbidities; and (5) the available and potential therapeutic strategies. We searched PubMed to identify original studies about psychedelics and Hallucinogen Persisting Perception Disorder (HPPD). Our research yielded a total of 45 papers, which have been analyzed and tabled to provide readers with the most updated and comprehensive literature review about the clinical features and treatment options for HPPD.
Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia
Authors: Bratek Ewelina , Ziembowicz Apolonia , Salinska Elzbieta
Published: March 2018

Hypoxia-ischemia (H-I) at the time of birth may cause neonatal death or lead to persistent brain damage. The search for an effective treatment of asphyxiated infants has not resulted in an effective therapy, and hypothermia remains the only available therapeutic strategy. Among possible experimental therapies, the induction of ischemic tolerance is promising. Recent investigations have shown that activation of group II metabotropic glutamate receptors (mGluR2/3) can provide neuroprotection against H-I, but the mechanism of this effect is not clear. The aim of this study was to investigate whether an mGluR2/3 agonist applied before H-I reduces brain damage in an experimental model of birth asphyxia and whether a decrease in oxidative stress plays a role in neuroprotection. Neonatal H-I on seven-day-old rats was used as an experimental model of birth asphyxia. Rats were injected intraperitoneally with the mGluR2/3 agonist LY379268 24 or 1 h before H-I (5 mg/kg). LY379268 reduced the infarct area in the ischemic hemisphere. Application of the agonist at both times also reduced the elevated levels of reactive oxygen species (ROS) in the ipsilateral hemisphere observed after H-I and prevented the increase in antioxidant enzyme activity in the injured hemisphere. The decrease in glutathione (GSH) level was also restored after agonist application. The results suggest that the neuroprotective mechanisms triggered by the activation of mGluR2/3 before H-I act through the decrease of glutamate release and its extracellular concentration resulting in the inhibition of ROS production and reduction of oxidative stress. This, rather than induction of ischemic tolerance, is probably the main mechanism involved in the observed neuroprotection.
Renaissance Drawings of the 16th Century in the City of Lugo: Three Fountains from Gonzalo de la Bárcena’s Workshop
Authors: Franco Taboada José , Goy Diz Ana
Published: March 2018

Historically, urban fountains have been underestimated to the point of not being considered worthy of conservation. The foregoing reason, together with the lack of sufficient archaeological data on this type of element in the Renaissance city, makes it necessary to document and carry out graphic research to correct this deficiency and establish the relevance of these constructions. The present work shows, through the concrete case method, the analysis of three Renaissance fountains from the Spanish city of Lugo and the importance of these elements as urban landmarks that marked the essential lines of the development of cities after the medieval period. It also analyses the work of their constructors, who belonged to a workshop of plumbers and master builders from the historical territory of Trasmiera (Cantabria) and who took their art throughout the Spanish kingdom.
Variations in the U-Value Measurement of a Whole Dwelling Using Infrared Thermography under Controlled Conditions
Authors: Marshall Alex , Francou Johann , Fitton Richard , Swan William , Owen Jacob , Benjaber Moaad
Published: March 2018

U-values of building elements are often determined using point measurements, where infrared imagery may be used to identify a suitable location for these measurements. Current methods identify that surface areas exhibiting a homogeneous temperature—away from regions of thermal bridging—can be used to obtain U-values. In doing so, however, the resulting U-value is assumed to represent that entire building element, contrary to the information given by the initial infrared inspection. This can be problematic when applying these measured U-values to models for predicting energy performance. Three techniques have been used to measure the U-values of external building elements of a full-scale replica of a pre-1920s U.K. home under controlled conditions: point measurements, using heat flux meters, and two variations of infrared thermography at high and low resolutions. U-values determined from each technique were used to calibrate a model of that building and predictions of the heat transfer coefficient, annual energy consumption, and fuel cost were made. Point measurements and low-resolution infrared thermography were found to represent a relatively small proportion of the overall U-value distribution. By propagating the variation of U-values found using high-resolution thermography, the predicted heat transfer coefficient (HTC) was found to vary between 183 W/K to 235 W/K (±12%). This also led to subsequent variations in the predictions for annual energy consumption for heating (between 4923 kWh and 5481 kWh, ±11%); and in the predicted cost of that energy consumption (between £227 and £281, ±24%). This variation is indicative of the sensitivity of energy simulations to sensor placement when carrying out point measurements for U-values.
New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response
Authors: Szymonowicz Klaudia , Oeck Sebastian , Malewicz Nathalie , Jendrossek Verena
Published: March 2018

Genetic alterations driving aberrant activation of the survival kinase Protein Kinase B (Akt) are observed with high frequency during malignant transformation and cancer progression. Oncogenic gene mutations coding for the upstream regulators or Akt, e.g., growth factor receptors, RAS and phosphatidylinositol-3-kinase (PI3K), or for one of the three Akt isoforms as well as loss of the tumor suppressor Phosphatase and Tensin Homolog on Chromosome Ten (PTEN) lead to constitutive activation of Akt. By activating Akt, these genetic alterations not only promote growth, proliferation and malignant behavior of cancer cells by phosphorylation of various downstream signaling molecules and signaling nodes but can also contribute to chemo- and radioresistance in many types of tumors. Here we review current knowledge on the mechanisms dictating Akt’s activation and target selection including the involvement of miRNAs and with focus on compartmentalization of the signaling network. Moreover, we discuss recent advances in the cross-talk with DNA damage response highlighting nuclear Akt target proteins with potential involvement in the regulation of DNA double strand break repair.
Recent Progress in Asymmetric Catalysis and Chromatographic Separation by Chiral Metal–Organic Frameworks
Authors: Bhattacharjee Suchandra , Khan Muhammad , Li Xiaofang , Zhu Qi-Long , Wu Xin-Tao
Published: March 2018

Metal–organic frameworks (MOFs), as a new class of porous solid materials, have emerged and their study has established itself very quickly into a productive research field. This short review recaps the recent advancement of chiral MOFs. Here, we present simple, well-ordered instances to classify the mode of synthesis of chiral MOFs, and later demonstrate the potential applications of chiral MOFs in heterogeneous asymmetric catalysis and enantioselective separation. The asymmetric catalysis sections are subdivided based on the types of reactions that have been successfully carried out recently by chiral MOFs. In the part on enantioselective separation, we present the potentiality of chiral MOFs as a stationary phase for high-performance liquid chromatography (HPLC) and high-resolution gas chromatography (GC) by considering fruitful examples from current research work. We anticipate that this review will provide interest to researchers to design new homochiral MOFs with even greater complexity and effort to execute their potential functions in several fields, such as asymmetric catalysis, enantiomer separation, and chiral recognition.
The Influence of Aluminizing Process on the Surface Condition and Oxidation Resistance of Ti–45Al–8Nb–0.5(B, C) Alloy
Authors: Szkliniarz Wojciech , Moskal Grzegorz , Szkliniarz Agnieszka , Swadźba Radosław
Published: March 2018

One of the major barriers limiting the suitability of TiAl intermetallic alloys for use in the demanding aircraft and automotive industries is their susceptibility to degradation as a result of oxidation at temperatures exceeding 760 °C. Paper presents the characteristics of resistance to cyclic oxidation at 950 °C for Ti–45Al–8Nb–0.5(B, C) alloy with and without protective coating obtained as a result of aluminizing using out of pack method. The characteristics of surface condition were determined by scanning electron microscope with EDS system, transmission electron microscope, and X-ray diffractometer. The favorable behavior of the Ti–45Al–8Nb–0.5(B, C) alloy with a protective coating under cyclic oxidation conditions is a result of a higher content of Al2O3 in the microstructure of the scale and the presence of Al and Nb-rich phases at the substrate interface, which probably constitue a barrier for oxidation process. The high temperature oxidation test revealed that aluminide coating was responsible for a remarkable improvement in the oxidation resistance.
Temperature Dependence of Crystal Structures and Band Parameters in Quantum Spin Liquid β′-EtMe3Sb[Pd(dmit)2]2 and Related Materials
Authors: Ueda Kohei , Tsumuraya Takao , Kato Reizo
Published: March 2018

In an isostructural series of anion radical salts β′-(Me4-xEtxZ)[Pd(dmit)2]2 (Z = P, As, Sb; x = 0, 1, 2), [Pd(dmit)2]2− units form a two-dimensional Mott insulator layer with a quasi-isosceles triangular lattice. The anisotropy of the triangular lattice is characterized by a ratio of interdimer transfer integrals, t′/t. The crystal structures of EtMe3Sb, Me4Sb, Me4As, and Et2Me2As salts were determined in the range of 5–295 K by the single crystal X-ray diffraction technique. Interdimer transfer integrals, Fermi surface, and band structures at low temperatures were calculated by the tight binding method and the first-principles density-functional theory (DFT) method based on experimentally obtained crystal structures. Interdimer transfer integrals increased with lowering temperature. At 5 K, the ratio t′/t decreased by about 15% from the room temperature value in every salt. The relationship between the transfer integrals and interdimer S⋯S distances indicated that the change of the t′/t value with temperature was due to a thermal contraction, rather than the arch-shaped molecular distortion of the Pd(dmit)2 molecule associated with the cation dependence of t′/t.