bluuebunny/crossref_metadata_2025 huggingface dataset:
A Thirty-Seven-Year Follow-Up of Peutz–Jeghers Syndrome across Three Generations / Tridesetsedmogodišnje praćenje Pojc-Jegersovog sindroma kroz tri generacije
Authors: Mojsilović Marijola , Katić Vuka , Ilić Ivan , Radovanović Biljana , Petrović Bratislav , Lazić Miodrag , Krstić Marijana
Published: February 2016

Peutz-Jeghers syndrome (PJS) is a rare genetic disorder with autosomal-dominant pleiotropic inheritance, variable penetrance and characteristic signs of the disease that predisposes persons to increased risk of developing cancer, particularly in the gastrointestinal tract and the breast. Due to genetic nature of disease, in the familial Peutz-Jeghers syndrome, a multiplication of symptoms in the three-generation family members was established.

This paper represents an insight into the anamnesis of PJS in one family over thirty-seven years of follow-up, and is part of the broader study of this disorder. Article presents family history, clinical and histological findings and multiplication of symptoms of PJS across three generations.

Over thirty-seven years, PJS has been present in this family in the form of only mucocutaneous pigmentation but without clinically manifested signs (father), or with both melanine hyperpigmentation and gastrointestinal hamartomatous polyposis (his daughter and her son).

The symptoms rose suspicion of the existence of PJS complication, i.e. carcinoid-like syndrome with watery diarrheas accompanied by constipations in the affected mother and son who were surgically treated. Diagnosis of PJS was histopathologically confirmed in both cases: the presence of the polyps with hamartomatous pattern and conspicuous hyperplasia of chromogranin-positive (EC and L cells) and serotoninpositive (EC) cells. Malignant transformation of PJ- removed polyps was not found. Besides hamartoma, polyps as well as a tubular adenoma were found, with a low degree dysplasia without malignant transformation (son).

The authors discuss the findings in relation to the important role of the gastrointestinal endocrine cell hyperplasia, not only for better understanding of the growth and clinical symptoms of the PJ polyposis, but also for new approach and the possible application of anti-hormonal therapy in the treatment of these patients in the future, that is not currently in use.
The Experimental Investigation Of The Screen Operation In The Parametric Resonance Conditions
Authors: Bąk Łukasz , Noga Stanisław , Stachowicz Feliks
Published: February 2016

In this paper the experimental studies of the screen working in the parametric resonance condition are discussed. The investigations are conducted for laboratory parametric resonance screen. The measuring test is performed for four cases of tension force values. The full sheet metal instead of the sieve is used. For each considered case the natural frequency of the plate and the parameter modulation frequency are determined. The achieved results are presented and discussed. It is shown that the highest sieve plate amplitude is obtained when the parameter modulation frequency is two times larger than natural frequency of the sieve plate. This parametric resonance vibration was observed only for tension force equal to 4000 N because of the rotational speed limits of electrical vibratos.
Fluidic Generator Of Microbubbles – Oscillator With Gas Flow Reversal For A Part Of Period
Authors: Tesař Václav
Published: February 2016

Paper presents a fluidic device developed for generation of small (less than 1 mm in diameter) microbubbles in a liquid from gas passing gas through small passages. Until now the bubbles are larger than the size of aerator passage exits so that making the passages smaller did not result in obtaining the desirable microbubbles. Analysis of high-speed camera images (obtained with a special lens of large working distance) have shown show that the large bubble size is caused by slow ascent motion of very small bubbles so that they get into mutual contact and grow by conjunction. The solution is to pulsate the supplied gas flow by a no-moving-part fluidic oscillator. The generated small bubble is moved back into the aerator passage where it is for a part of oscillation period protected from the conjunction with other, previously generated microbubbles.
Cyclic Linear Random Process As A Mathematical Model Of Cyclic Signals
Authors: Lupenko Sergiy , Lutsyk Nadiia , Lapusta Yuri
Published: February 2016

In this study the cyclic linear random process is defined, that combines the properties of linear random process and cyclic random process. This expands the possibility describing cyclic signals and processes within the framework of linear random processes theory and generalizes their known mathematical model as a linear periodic random process. The conditions for the kernel are given and the probabilistic characteristics of generated process of linear random process in order to be a cyclic random process. The advantages of the cyclic linear random process are presented. It can be used as the mathematical model of the cyclic stochastic signals and processes in various fields of science and technology.
Real Time Trajectory Correction System Of Optical Head In Laser Welding
Authors: Cieszyński Wojciech , Zięba Michał , Reiner Jacek
Published: February 2016

Application of laser welding technology requires that the laser beam is guided through the whole length of the joint with sufficiently high accuracy. This paper describes result of research on development of optomechatronic system that allows for the precise positioning of the laser head’s TCP point on the edge of welded elements during laser processing. The developed system allows for compensation of workpiece’s fixture inaccuracies, precast distortions and workpiece deformations occurring during the process.
Value of a commercial kit for detecting anti-C1q autoantibodies and correlation with immunological and clinical activity of lupus nephritis
Authors: de Liso Federica , Matinato Caterina , Novembrino Cristina , Radice Antonella , Raffiotta Francesca , Ronchi Mariangela , Croci Maria Daniela , Sinico Renato Alberto , Messa Piergiorgio , Torresani Erminio , Moroni Gabriella
Published: February 2016

The association of anti-C1q antibodies (anti-C1q) with the renal activity of lupus nephritis (LN) and the methods for their determination is still a matter of debate.

In 116 serum samples of 66 patients with biopsy proven LN, we aimed: 1) to compare the results of the determination of anti-C1q obtained by a commercial kit with a clinically validated in-house ELISA; 2) to evaluate the correlation of anti-C1q with the most important immunological and clinical parameters employed in LN, i.e., antibodies to dsDNA (anti-dsDNA), C3 and C4 complement component, haemoglobin and haematuria.

Good correlation and agreement between the two methods (r=0.81, p<0.0001; contingency coefficient=0.70, p<0.0001, respectively) were demonstrated. No differences were observed between the two assays by ROC curves comparison. Anti-C1q levels were significantly higher in patients with active LN [44 arbitrary units (AUs)] in comparison to those with inactive LN (23 AUs, p=0.047) and significantly correlated with anti-dsDNA (r=0.44, p<0.0001), complement fractions (C3: r=−0.33, p=0.001; C4: r=−0.29, p=0.003), haemoglobin levels (r=−0.34, p=0.0004) and the number of urinary red blood cells (r=0.26, p=0.01).

Our results suggest the validity of this commercial assay in detecting anti-C1q and confirm the association of anti-C1q with renal involvement of LN and the importance of introducing this parameter in the analytical panel for the evaluation of LN activity.
Machine Meets Man: Evaluating the Psychological Reality of Corpus-based Probabilistic Models
Authors: Divjak Dagmar , Dąbrowska Ewa , Arppe Antti
Published: February 2016

Linguistic convention typically allows speakers several options. Evidence is accumulating that the various options are preferred in different contexts, yet the criteria governing the selection of the appropriate form are often far from obvious. Most researchers who attempt to discover the factors determining a preference rely on the linguistic analysis and statistical modeling of data extracted from large corpora. In this paper, we address the question of how to evaluate such models and explicitly compare the performance of a statistical model derived from a corpus with that of native speakers in selecting one of six Russian TRY verbs. Building on earlier work we trained a polytomous logistic regression model to predict verb choice given the sentential context. We compare the predictions the model makes for 60 unseen sentences to the choices adult native speakers make in those same sentences. We then look in more detail at the interplay of the contextual properties and model computationally how individual differences in assessing the importance of contextual properties may impact the linguistic knowledge of native speakers. Finally, we compare the probability the model assigns to encountering each of the six verbs in the 60 test sentences to the acceptability ratings the adult native speakers give to those sentences. We discuss the implications of our findings for both usage-based theory and empirical linguistic methodology.
Contribution to the Research on Rural Resorts in the Function of Tourism Products and Services Distribution: the Example of the Republic of Croatia
Authors: Demonja Damir , Gredičak Tatjana
Published: February 2016

The primary function of the rural resort is to renovate and put into function existing, old, abandoned buildings/constructions, giving them a new purpose for tourism services. At the same time, construction of new buildings/structures, which can distort the authentic rural environment, is reduced. This paper intends to identify and analyse the elements of the tourism market in the Republic of Croatia which affect the process of revitalisation of the historic settlements through tourism products and services, while these elements are maintained, and popularise traditional culture and create an additional source of income in the countryside. The aim is to explore the place and role of rural resorts to enhance the distribution of tourism products and services, and the relevance of the application/use of tourist valorisation potentials of rural areas in the continuous efforts of improving tourism in the Republic of Croatia. The above is presented through a marketing policy and destination and space management, with a focus on limiting administrative, organisational and financial factors that influence the prosperity growth and substantial investment cycles in this segment in the Republic of Croatia.
Implementation of the Natura 2000 Network in Poland – an Opportunity or a Threat to Sustainable Development of Rural Areas? Study on Local Stakeholders’ Perception1
Authors: Chmielewski Waldemar , Głogowska Magdalena
Published: February 2016

Conflicts related to the implementation of the Natura 2000 network can be found in Poland and other European countries. The general causes of those conflicts are known. Some of them lie in the habitat directive itself, and others are related to the transposition of the directive into national environmental law and management systems. The designation of Natura 2000 sites in Poland involved strong protests on a local level, mainly due to the lack of consultations with the stakeholders, or at least with the local governments. In those days, the common argument against the implementation of Natura 2000 was one of severe restrictions on the conduct of economic activities and infrastructure development. Eight years after the official implementation of Natura 2000 in Poland, we would like to state the research question as follows: “Is Natura 2000 a constraint on local development?”

The paper presents the results of the research on the conflicts related to the Natura 2000 sites in Poland, and a perception of the Natura 2000 impact on the local economy, local community, and local citizens’ own situation, based on the questionnaire surveys conducted at the meetings, where management plans of the Natura 2000 sites were discussed.

It appears that despite many cases of conflicts related to economical activities, new investments or infrastructure identified in municipalities with Natura 2000 sites in Poland, local stakeholders do not consider Natura 2000 only to be a restraint, but also an opportunity.
Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study
Authors: Martins Ana M. , Tanbour Rafeeq , Elkhodiry Mohammed A. , Husseini Ghaleb A.
Published: February 2016

The aim of this work is to study the kinetics of ultrasound (70 kHz) – using a kinetic model that takes into account cavitation events and drug re-encapsulation upon the cessation of the acoustic field. The simulation allowed the determination of three parameters
Modelling of Muscle Force Distributions During Barefoot and Shod Running
Authors: Sinclair Jonathan , Atkins Stephen , Richards Jim , Vincent Hayley
Published: February 2016

Research interest in barefoot running has expanded considerably in recent years, based around the notion that running without shoes is associated with a reduced incidence of chronic injuries. The aim of the current investigation was to examine the differences in the forces produced by different skeletal muscles during barefoot and shod running. Fifteen male participants ran at 4.0 m·s-1 (± 5%). Kinematics were measured using an eight camera motion analysis system alongside ground reaction force parameters. Differences in sagittal plane kinematics and muscle forces between footwear conditions were examined using repeated measures or Freidman’s ANOVA. The kinematic analysis showed that the shod condition was associated with significantly more hip flexion, whilst barefoot running was linked with significantly more flexion at the knee and plantarflexion at the ankle. The examination of muscle kinetics indicated that peak forces from Rectus femoris, Vastus medialis, Vastus lateralis, Tibialis anterior were significantly larger in the shod condition whereas Gastrocnemius forces were significantly larger during barefoot running. These observations provide further insight into the mechanical alterations that runners make when running without shoes. Such findings may also deliver important information to runners regarding their susceptibility to chronic injuries in different footwear conditions.
Certain Actions from the Functional Movement Screen Do Not Provide an Indication of Dynamic Stability
Authors: Lockie Robert G. , Callaghan Samuel J. , Jordan Corrin A. , Luczo Tawni M. , Jeffriess Matthew D. , Jalilvand Farzad , Schultz Adrian B.
Published: February 2016

Dynamic stability is an essential physical component for team sport athletes. Certain Functional Movement Screen (FMS) exercises (deep squat; left- and right-leg hurdle step; left- and right-leg in-line lunge [ILL]; left- and right-leg active straight-leg raise; and trunk stability push-up [TSPU]) have been suggested as providing an indication of dynamic stability. No research has investigated relationships between these screens and an established test of dynamic stability such as the modified Star Excursion Balance Test (mSEBT), which measures lower-limb reach distance in posteromedial, medial, and anteromedial directions, in team sport athletes. Forty-one male and female team sport athletes completed the screens and the mSEBT. Participants were split into high-, intermediate-, and low-performing groups according to the mean of the excursions when both the left and right legs were used for the mSEBT stance. Any between-group differences in the screens and mSEBT were determined via a one-way analysis of variance with Bonferroni post hoc adjustment (p < 0.05). Data was pooled for a correlation analysis (p < 0.05). There were no between-group differences in any of the screens, and only two positive correlations between the screens and the mSEBT (TSPU and right stance leg posteromedial excursion, r = 0.37; left-leg ILL and left stance leg posteromedial excursion, r = 0.46). The mSEBT clearly indicated participants with different dynamic stability capabilities. In contrast to the mSEBT, the selected FMS exercises investigated in this study have a limited capacity to identify dynamic stability in team sport athletes.
Higher Neuromuscular Manifestations of Fatigue in Dynamic than Isometric Pull-Up Tasks in Rock Climbers
Authors: Boccia Gennaro , Pizzigalli Luisa , Formicola Donato , Ivaldi Marco , Rainoldi Alberto
Published: February 2016

Neuromuscular assessment of rock climbers has been mainly focused on forearm muscles in the literature. We aimed to extend the body of knowledge investigating on two other upper limb muscles during sport-specific activities in nine male rock climbers. We assessed neuromuscular manifestations of fatigue recording surface electromyographic signals from brachioradialis and teres major muscles, using multi-channel electrode arrays. Participants performed two tasks until volitional exhaustion: a sequence of dynamic pull-ups and an isometric contraction sustaining the body at half-way of a pull-up (with the elbows flexed at 90°). The tasks were performed in randomized order with 10 minutes of rest in between. The normalized rate of change of muscle fiber conduction velocity was calculated as the index of fatigue. The time-to-task failure was significantly shorter in the dynamic (31 ±10 s) than isometric contraction (59 ±19 s). The rate of decrease of muscle fiber conduction velocity was found steeper in the dynamic than isometric task both in brachioradialis (isometric: −0.2 ±0.1%/s; dynamic: −1.2 ±0.6%/s) and teres major muscles (isometric: −0.4±0.3%/s; dynamic: −1.8±0.7%/s). The main finding was that a sequence of dynamic pull-ups lead to higher fatigue than sustaining the body weight in an isometric condition at half-way of a pull-up. Furthermore, we confirmed the possibility to properly record physiological CV estimates from two muscles, which had never been studied before in rock climbing, in highly dynamic contractions.
Comparison of Lower Limb Segments Kinematics in a Taekwondo Kick. An Approach to the Proximal to Distal Motion
Authors: Estevan Isaac , Falco Coral , Silvernail Julia Freedman , Jandacka Daniel
Published: February 2016

In taekwondo, there is a lack of consensus about how the kick sequence occurs. The aim of this study was to analyse the peak velocity (resultant and value in each plane) of lower limb segments (thigh, shank and foot), and the time to reach this peak velocity in the kicking lower limb during the execution of the roundhouse kick technique. Ten experienced taekwondo athletes (five males and five females; mean age of 25.3 ±5.1 years; mean experience of 12.9 ±5.3 years) participated voluntarily in this study performing consecutive kicking trials to a target located at their sternum height. Measurements for the kinematic analysis were performed using two 3D force plates and an eight camera motion capture system. The results showed that the proximal segment reached a lower peak velocity (resultant and in each plane) than distal segments (except the peak velocity in the frontal plane where the thigh and shank presented similar values), with the distal segment taking the longest to reach this peak velocity (p < 0.01). Also, at the instant every segment reached the peak velocity, the velocity of the distal segment was higher than the proximal one (p < 0.01). It provides evidence about the sequential movement of the kicking lower limb segments. In conclusion, during the roundhouse kick in taekwondo inter-segment motion seems to be based on a proximo-distal pattern.
Focused and Radial Shock Wave Therapy in the Treatment of Tennis Elbow: A Pilot Randomised Controlled Study
Authors: Król Piotr , Franek Andrzej , Durmała Jacek , Błaszczak Edward , Ficek Krzysztof , Król Barbara , Detko Ewa , Wnuk Bartosz , Białek Lidia , Taradaj Jakub
Published: February 2016

The purpose of this article was to evaluate and compare the efficacy of radial and focused shock wave therapies applied to treat tennis elbow. Patients with tennis elbow were randomized into two comparative groups: focused shock wave therapy (FSWT; n=25) and radial shock wave therapy (RSWT; n=25). Subjects in the FSWT and RSWT groups were applied with a focused shock wave (3 sessions, 2000 shocks, 4 Hz, 0.2 mJ/mm2) and a radial shock wave (3 sessions, 2000 + 2000 shocks, 8 Hz, 2.5 bar), respectively. The primary study endpoints were pain relief and functional improvement (muscle strength) one week after therapy. The secondary endpoint consisted of the results of the follow-up observation (3, 6 and 12 weeks after the study). Successive measurements showed that the amount of pain patients felt decreased in both groups. At the same time grip strength as well as strength of wrist extensors and flexors of the affected extremity improved significantly. Both focused and radial shock wave therapies can comparably and gradually reduce pain in subjects with tennis elbow. This process is accompanied by steadily improved strength of the affected extremity.
Moderate Altitude Affects High Intensity Running Performance in a Collegiate Women’s Soccer Game
Authors: Bohner Jonathan D. , Hoffman Jay R. , McCormack William. P. , Scanlon Tyler C. , Townsend Jeremy R. , Stout Jeffrey R. , Fragala Maren S. , Fukuda David H.
Published: February 2016

The effect of altitude on soccer game activity profiles was retrospectively examined in six NCAA Division I female soccer players. Comparisons were made between two matches played at sea level (SL) and one match played at a moderate altitude (1839 m). A 10-Hz global positioning system device was used to measure distance and velocity. The rate of total distance capacity (TDC) and high intensity running (HIR) as well as percent of time at HIR were evaluated. Significant differences were seen in the distance rate (120.55 ± 8.26 m·min-1 versus 105.77 ± 10.19 m·min-1) and the HIR rate (27.65 ± 9.25 m·min-1 versus 25.07 ± 7.66 m·min-1) between SL and altitude, respectively. The percent of time at HIR was not significantly different (p = 0.064), yet tended to be greater at SL (10.4 ± 3.3%) than at altitude (9.1 ± 2.2%). Results indicate that teams residing at SL and competing at a moderate altitude may have a reduced ability in distance covered and a high intensity run rate.
Effects of Single Vs. Multiple Sets Water-Based Resistance Training on Maximal Dynamic Strength in Young Men
Authors: Buttelli Adriana Cristine Koch , Pinto Stephanie Santana , Schoenell Maira Cristina Wolf , Almada Bruna Pereira , Camargo Liliana Kologeski , de Oliveira Conceição Matheus , Kruel Luiz Fernando Martins
Published: February 2016

The aim of this study was to compare the effects of single vs. multiple sets water-based resistance training on maximal dynamic strength in young men. Twenty-one physically active young men were randomly allocated into 2 groups: a single set group (SS, n=10) and a multiple sets group (MS, n=11). The single set program consisted of only 1 set of 30 s, whereas the multiple sets comprised 3 sets of 30 s (rest interval between sets equaled 1 min 30 s). All the water-based resistance exercises were performed at maximal effort and both groups trained twice a week for 10 weeks. Upper (bilateral elbow flexors and bilateral elbow extensors, peck deck and inverse peck deck) as well as lower-body (bilateral knee flexors and unilateral knee extensors) one-repetition maximal tests (1RM) were used to assess changes in muscle strength. The training-related effects were assessed using repeated measures two-way ANOVA (α=5%). Both SS and MS groups increased the upper and lower-body 1RM, with no differences between groups. Therefore, these data show that the maximal dynamic strength significantly increases in young men after 10 weeks of training in an aquatic environment, although the improvement in the strength levels is independent of the number of sets performed.
Does the GNB3 C825T Polymorphism Influence Swimming Performance in Competitive Swimmers?
Authors: Grenda Agata , Sawczuk Marek , Kaczmarczyk Mariusz , Maciejewska Agnieszka , Umiastowska Danuta , Łubkowska Wioletta , Żmijewski Piotr , Cięszczyk Paweł
Published: February 2016

Single nucleotide polymorphism C825T located within the GNB3 gene has been proposed in the literature as the performance enhancing polymorphism in highly trained athletes. Therefore, the aim of the present study was to verify the hypothesis assuming an association between the C825T polymorphic site and performance of competitive swimmers. The frequencies of C/T alleles and distribution of CC, CT and TT genotypes of the C825T GNB3 polymorphism were compared between athletes and nonathletic controls as well as between sprint and endurance swimmers. Genomic DNA was extracted from 197 competitive swimmers (50 long distance swimmers (LDS) and 147 short distance swimmers (SDS)) and 379 sedentary volunteers. The allele frequencies and genotype distribution of the C825T polymorphic site were not significantly different when LDS and SDS were compared to sedentary controls. Gender-specific analysis did not reveal any significant differences in allele and genotype distribution, neither between female controls and female swimmers nor between male controls and male swimmers. No significant differences in allele frequencies and genotype distribution were observed when LDS and SDS as well as groups of swimmers stratified by gender were compared. The results of this study do not support the hypothesis that the C825T polymorphism of the GNB3 gene is associated with swimming performance in competitive swimmers.
Structural Analysis of Technical-Tactical Elements in Table Tennis and their Role in Different Playing Zones
Authors: Munivrana Goran , Petrinović Lidija Zekan , Kondrič Miran
Published: February 2016

For the purpose of determining the overall structure of technical-tactical elements in table tennis and evaluating their role in different playing zones around the table, a new measuring instrument (a questionnaire) was formulated that took advantage of the expert knowledge of top, world class table tennis coaches. The results of the hierarchical taxonomic (cluster) analysis showed that the overall structure of the technical-tactical elements forming the table tennis technique could be divided into three basic groups; a group of technical-tactical elements (A) used in the phase of preparing one’s own and disabling the opponent’s attack; a group of technical-tactical elements (B) used in the phase of attack and counterattack; and a group of technical-tactical elements (C) used in the phase of defense. The differences among the obtained groups of table tennis elements were determined by applying the Kruskal-Wallis test, while relations between the groups and their role in different playing zones around the table were analyzed by comparing the average values of the experts’ scores.
Influence of the Type of Marking and the Number of Players on Physiological and Physical Demands During Sided Games in Soccer
Authors: Casamichana David , Román-Quintana Jaime San , Castellano Julen , Calleja-González Julio
Published: February 2016

The aim of this research was to examine the influence of two variables, the type of marking (with or without man-marking) and the number of players per team (3, 6, or 9) on the physical and physiological demands of sided games in soccer. Eighteen amateur players were monitored with GPS and heart rate devices. The following variables were analyzed: a maximum heart rate, a mean heart rate, time spent in each intensity range, total distance covered and distance covered in different speed ranges, a player load, maximum speed reached, and a work:rest ratio. The results showed that the type of marking influenced the physical demands of players, with greater total distance, a player load and a work:rest ratio when man-marking was used in the 3 vs. 3 (737 m, 95 Arbitrary Units (AU) and 3.4 AU, respectively) and 6 vs. 6 (783 m, 95 AU and 5.3 AU, respectively) games (p<0.05). The number of players also had an effect on physiological intensity, with more time being spent at the <80%HRmax during the 9 vs. 9 and 6 vs. 6 games (more than 30%) compared with the 3 vs. 3 format (less than 15%) (p<0.05). These findings could help coaches to understand how the modification of different variables in sided games influences the physical and physiological demands of players.
The Intricacies of Children’s Physical Activity
Authors: Brusseau Timothy A
Published: February 2016

Understanding the physical activity patterns of youth is an essential step in preparing programming and interventions needed to change behavior. To date, little is known about the intricacies of youth physical activity across various physical activity segments (i.e. in school, out of school, recess, classroom physical activity, physical education, weekends, etc.). Therefore, the purpose of the study was to examine the physical activity patterns of elementary school children across various segments and during two seasons. A total of 287 fourth and fifth graders from the Southwest US wore the Yamax Digiwalker SW-200 pedometer for 7 consecutive days during the Fall and Spring seasons. Children were prompted to record their step counts when arriving and leaving school, before and after physical education and recess, as well as on the weekends. Means and standard deviations were calculated and ANOVAs and t tests were utilized to examine difference by sex, season, and segment. Youth were more active outside of school and on weekdays (p<0.05). Boys were generally more active than girls and all youth were more active during the milder Spring season. There is a clear need for Comprehensive School Physical Activity Programming and weekend physical activity opportunities. Furthermore, greater emphasis is needed on PE and across other activity segments for girls to increase their physical activity levels.
A Model on the Stability of a Pipe in an Aerated Silo
Authors: Barletta Diego , Poletto Massimo
Published: February 2016

The limiting aeration condition necessary to produce the collapse of established pipes (ratholes) is evaluated in a powder bed stored in a flat-bottomed aerated silo. The main parameters tested are the powder properties and the width of the aeration pad at the silo bottom. The measured quantities are the aeration rate and the corresponding size of the pipe. The gas pressure gradient close to the pipe is estimated from the numerical solution of the air flow field in the bulk solids assuming the Darcy flow regime. The powder permeability necessary for this calculation is estimated by fluidization experiments. The hoop stress evaluated according to Johanson (2004) is in good agreement with the unconfined yield strength of the powder, provided that the contribution of aeration to powder consolidation during the pipe formation is properly accounted for.
An Effective Reaction Rate Model for Gas-Solid Reactions with High Intra-Particle Diffusion Resistance
Authors: Yang Wei , Cloete Schalk , Morud John , Amini Shahriar
Published: February 2016

An approximate analytical expression for estimating the effectiveness factors of non-catalytic gas-solid reactions is proposed. The new expression is derived from the analytical solution for simple first order reactions (Ishida and Wen 1968. Comparison of kinetic and diffusional models for solid-gas reactions. AIChE Journal 14, 311–317. http://dx.doi.org/10.1002/aic.690140218). The scaled Thiele modulus concept is introduced to account for the variations of the reaction rate form that differs from the first order. The validity of the new expression is demonstrated for the reactions of different orders and of different forms via comparisons against a complete particle-reactor model using the collocation method for solving heat and mass fluxes inside the particles. In addition, the proposed approach is applied to redox reactions of ferric oxide where non-isothermal condition, net consumption of gaseous reactant, and parallel reactions are encountered. The results show that the effectiveness factor method compared well with the orthogonal collocation method over a wide range of Thiele moduli, reaction orders and reaction forms. Therefore, the proposed expression can serve as a generic replacement for more complex and computationally expensive combined particle-reactor modelling which is often employed in reactor systems with significant intra-particle diffusion resistances.
The Optimized Operation of Gas Turbine Combined Heat and Power Units Oriented for the Grid-Connected Control
Authors: Xia Shu , Ge Xiaolin
Published: February 2016

In this study, according to various grid-connected demands, the optimization scheduling models of Combined Heat and Power (CHP) units are established with three scheduling modes, which are tracking the total generation scheduling mode, tracking steady output scheduling mode and tracking peaking curve scheduling mode. In order to reduce the solution difficulty, based on the principles of modern algebraic integers, linearizing techniques are developed to handle complex nonlinear constrains of the variable conditions, and the optimized operation problem of CHP units is converted into a mixed-integer linear programming problem. Finally, with specific examples, the 96 points day ahead, heat and power supply plans of the systems are optimized. The results show that, the proposed models and methods can develop appropriate coordination heat and power optimization programs according to different grid-connected control.
Attenuation of genotoxicity, oxidative stress, apoptosis and inflammation by rutin in benzo(a)pyrene exposed lungs of mice: plausible role of NF-κB, TNF-α and Bcl-2
Authors: Shahid Ayaz , Ali Rashid , Ali Nemat , Kazim Hasan Syed , Rashid Summya , Majed Ferial , Sultana Sarwat
Published: February 2016

Background: Benzo(a)pyrene [B(a)P] is an environmental contaminant and potential carcinogenic agent that causes lung injuries which leads to lung cancer. Rutin, a well-known flavonoid present in various natural sources, possesses biological activities such as anti-oxidative and anti-inflammatory properties. The aim of this study was to evaluate the protective effects of rutin against B(a)P-induced genotoxicity, oxidative stress, apoptosis and inflammation in Swiss albino mice.

Methods: Pretreatment of rutin was given by oral gavage at doses of 40 and 80 mg/kg body weight (b.wt.) for 7 days before the administration of a single oral dose of B(a)P (125 mg/kg b.wt.). The ameliorative effect of rutin on oxidative stress, apoptotic and inflammatory markers in lung tissues and genotoxicity was studied using an alkaline unwinding assay and DNA fragmentation.

Results: B(a)P enhanced lipid peroxidation, xanthine oxidase, H2O2 generation and lactate dehydrogenase (LDH) activity; depleted activities of anti-oxidant enzymes and glutathione content; induced DNA strand breaks and fragmentation; disrupted normal histopathological architecture and also showed abnormal expression of NF-κB, COX-2, IL-6, TNF-α and Bcl-2. Rutin pretreatment caused a significant reduction in lipid peroxidation and LDH activity; increased glutathione content; restored antioxidant enzyme activity; reduced DNA strand breaks and fragmentation; modulated the expression of inflammatory, and apoptotic markers and restored the histopathological structure.

Conclusions: The findings of the present study supported the protective effect of rutin against B(a)P-induced lung toxicity and genotoxicity.
Compression for trace zero points on twisted Edwards curves
Authors: Bianco Giulia , Gorla Elisa
Published: February 2016

We propose two optimal representations for the elements of trace zero subgroups of twisted Edwards curves.
For both representations, we provide efficient compression and decompression algorithms. The efficiency of the algorithm
is compared with the efficiency of similar algorithms on elliptic curves in Weierstrass form.
Weyerhaeuser: A Good Reputation Instilled in Culture
Authors: Bochniarz Zbigniew , Lipiec Jacek
Published: February 2016

The paper addresses the concept of Weyerhaeuser’s culture which was transformed as the result of mergers and implemented policies against recession. The culture, particularly their long-term vision and values played a crucial role in Weyerhaeuser’s company. Frederick Weyerhaeuser, founder of the firm, realized that a firm’s reputation was the most important asset. Significant increases in housing demand over 1997-2005 had led to an enormous pressure for faster deliveries and innovations in the construction industry. Weyerhaeuser decided to become global leader by transforming its culture and launching the iLevel concept7.
Migrants, Assigned Expatriates (AE) and Self-initiated Expatriates (SIE) - Dfferentiation of Terms and Literature-Based Research Review
Authors: Przytuła Sylwia
Published: February 2016

The globalized world economy demand increasing global mobility and flexibility in the workplace and workforce. More and more skilled individuals seek international career opportunities. Thera are various mobile employees in the international context [OECD] among which are migrants, assigned expatriates (AE) and self-initiated expatriates (SIE). Many people experience international mobility through migration or as part of an expatriate assignment [Banai, Harry 2004; Capellen, Jansenss 2010; Dickman, Doherty 2010; Zikic et all 2010]. Yet an increasing number are choosing self-initiation expatriation [Bozionelos 2009; Selmer, Lauring 2010; Tharenou 2010; Doherty et all, 2013].

The purpose of this article is to enhance the conceptual coherence of the notion of migrant and assigned expatriate (AE) and self-initiated expatriate (SIE). Proposed definitions are based on a set of conceptual criteria which differentiates these three types of international movers.
Tourism Product as a Tool Shaping Cross-cultural Approach in Marketing
Authors: Marciszewska Barbara , Grobelna Aleksandra
Published: February 2016

One of the earlier definitions of cross-cultural management focuses on its behavioral aspects and underlines an importance of interaction of people from different cultures. “Cross-cultural management is the study of the behavior of people in organizations located in cultures and nations around the world” [Adler 1983, p. 226]. This definition is based on the description of organizational behavior within countries and cultures on one hand and of organizational behavior across countries and cultures on another. Peoples from different countries often work together in the same environment creating specific interactions but they can also built special relationships during their leisure time.

Looking at the particular subject of management from this perspective it is possible to notice that tourism products have quite big potential for creating cross-cultural interactions when services are produced in different cultures or/and consumed in different cultural context. It is mainly connected with a simultaneous production and consumption on the one hand and consumer’s participation in both processes on the other hand. Tourism products posses an additional feature which creates a cross-cultural dimension in both production and consumption: movement (traveling) between different cultural environments which is a source of different cultural experiences; they have to be recognized a priori to be placed on the market with the tourism product. On the other hand tourism services have to be produced according to identified consumer expectations in different cultures.

The aim of the study is to present selected aspects of tourism products which can create cross-cultural interactions and require a special managerial marketing approach. This article discusses an impact of cultural diversity on organizational behavior in international tourism and on consumer behavior in cultural tourism with a special focus on cross-cultural interactions in consumption of tourism products. This is connected with the fact that tourism products are produced and consumed by tourists in different cultures; this relationship can create specific interactions of many types.

The main research method applied is a literature review on cultural tourism and marketing.
Employee Appraisal as the Tool of the Pro-innovative Organizational Culture Formation in Hospitals36
Authors: Jończyk Joanna , Buchelt Beata
Published: February 2016

Healthcare sector is considered as the knowledge-based sector and because of this innovation and creativity should be regarded as prerequisite for the survival and growth of the organizations which perform their activities within the sector. In this context development of pro-innovative culture within hospitals becomes crucial. In search for tools allowing to create the culture employees appraisal becomes an interesting tool to be further investigated. Due to the fact the main aim of the paper is to investigate the relationships between the employee appraisal system and innovation in the context of the organizational culture in the hospitals. Study was carried in eight public hospitals located in two voivodships in Poland. Not only qualitative but also quantitative data was analyzed in order to identify usefulness of employees appraisal as the tool of pro-innovative culture creation.
Age Management within Organizations – Employees’ Perceptions of the Phenomenon – Research Report
Authors: Fornalczyk Agnieszka , Stompór-Świderska Jagoda , Ślazyk-Sobol Magdalena
Published: February 2016

This article discusses the issue of age management in organizations and presents research results concerning workers’ perceptions of the phenomenon. The aim of the research was to study the perceptions of Polish employees of various professional fields, check employees’ level of knowledge of the age management issue, determine the variables differentiating this knowledge and verify whether employees consider age management to be useful and how they perceive experienced workers.

The first part of the article presents concepts explaining what age management is in the context of demographic changes in European societies. Age management is a term encompassing a range of methods aiming at the possibly most effective use of human capital in organizations, irrespective of employees’ age, so that their work is efficient, profitable for the company as well as satisfying for the workers themselves. Strategies referring to age management should consider the perspectives of the company, employee, job market policy and demographic and economic situation conditions. In the later part of this article, the authors present the results of exploratory research into the level of knowledge of age management, the way it is perceived in organizations around Poland, mostly in international corporations. The research included employees of business and budget sectors. Respondents answered questionnaire questions by estimating, on the Likert scale, how they assess age management measures taken in their workplace, the need to use experienced workers’ potential, etc. In the authors’ opinion, because of the importance of the problem of efficient personnel management and promoting and applying age management programs, it is necessary for both employees and managers to have awareness, knowledge and positive attitude towards methods activating the potential of employees from various age ranges.
Intercultural Challenges Facing the Hospitality Industry. Implications for Education and Hospitality Management
Authors: Grobelna Aleksandra
Published: February 2016

Hospitality organizations which are increasingly operating internationally create real challenges for their employees and managers to interact and effectively work with people from different cultural environments. Many problems may relate to intercultural communication between managers and employees as well as between employees and hotel guests from different cultural backgrounds. Therefore, the issue of intercultural communication has recently had an increasing reach in the hospitality industry.

Cultural awareness, sensitivity and understanding of cultural differences should be perceived as a critical issue for business success. Therefore, the following questions still need answers from both academics and the business: What kind of challenges does the hospitality industry face in view of the multicultural diversity of its markets? What kind of managers’ skills and abilities, particularly in the case of entry-level managers, are strongly needed today to manage effectively multicultural hospitality workforce? And how may educational programs influence intercultural competence development of tourism and hospitality students to interact effectively in a multicultural environment. The aim of the study is to show that cultural diversity of hotel employees and guests may create unique challenges of cross-cultural service encounters, which may provide an opportunity for service differentiation.

The research problem is to find answers to the questions: how may the challenges that emerge from cross-cultural interactions become a source of hotel competitiveness and how may the educational process contribute to the intercultural competence development, to recruit employees who will be able to operate successfully in a multicultural hospitality environment.

The study problem is discussed in the context of literature review and the previous research conducted in the hospitality setting. Implications for practitioners and educators are also delivered.
The “Retro” Trend in Marketing Communication Strategy of Global Brands
Authors: Grębosz Magdalena , Pointet Jean-Marc
Published: February 2016

The main objective of this article is to present the relevance and possibilities of using the “retro” trend in marketing communication strategy of global brands, taking into account intercultural environment of companies. In the article the examples of retro-communication of global brands are presented. The results of comparative studies of attitudes of French and Polish consumers concerning retro communication campaigns of global brands are also analysed, taking into account the product category, as well as geographic and cultural consumers characteristics. The results of the research confirm the significance of retro marketing communication in case of global brands in current market conditions and their impact on consumers attitudes.
Immunohistochemical Detection of Estrogen Receptors in Canine Mammary Tumors
Authors: Atanaskova Petrov Elena , Gjurovski Ivica , Ristoski Trpe , Nikolovski Goran , Trenkoska Pandorce , Trojacanec Plamen , Ilievska Ksenija , Dovenski Toni , Petrushevska Gordana
Published: February 2016

Mammary tumors are among the most common neoplasms in intact female dogs. They have a complex morphology, usually affecting middle age and older bitches. Almost 50% of the mammary tumors in dogs are malignant neoplasms. Prognosis is based on several factors: stage, age, tumor size, metastasis, histopathology, ovariectomy status and hormone-receptor activity. Immunohistochemical (IHC) measurement has become increasingly an important diagnostic and prognostic parameter, with the development of monoclonal antibodies against nuclear estrogen and progestin receptors. The aim of this study was to detect the presence of ER receptors in malignant canine mammary tumors and to identify their association with the clinical course of the tumor. Mammary tumor samples have been obtained by mastectomy from dogs presented at our clinic. Detailed clinical examination, CBC and basic serum biochemical profile were performed in all patients. Surgery was the only treatment. Histopathological examination and immunohistochemical detection of estrogen α receptors (ERα) was performed on 8 formalin-fixed, paraffin-embedded tissue samples, using the PT LINK immunoperoxidase technique. Histopathological examination of the mammary tumor samples (n=11) revealed tubular adenocarcinoma (n=6,54.5%) and ductal adenocarcinoma (n=3, 27.3%), one patient with benign adenoma and one with mastitis. Patients with positive ER tumors are alive, without remission, while 3 of the patients that were ER negative died due to lung metastases. According to our results, it can be concluded that the appearance and development of canine mammary tumors is highly connected with ovarian steroid hormones and that immunostaining of the tumors may be used as a good prognostic parameter in these patients.