bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of The Efficacy of Letrozole Versus Danazol in Pain Relief in Endometriosis
Authors: Nawaz Sundus , Habib Sadia , Ayoub Saba , Shams Ghazala , Naeem Nimra , Sultana Ruqiya
Published: December 2022

Endometriosis is a chronic inflammatory disease defined as the presence of endometrium-like tissue outside the uterus which is responsive to the estrogen levels in blood circulation. Objective: To compare the efficacy of letrozole versus danazol in pain relief in endometriosis. Methods: This randomized controlled trial was conducted at the department of Obstetrics & Gynecology, Ayub Teaching Hospital, Abbottabad, Pakistan from January 2018 to December 2021. Patients diagnosed with endometriosis were enrolled and detailed medical history was taken. Patients were randomly divided into either Letrozole (n=120) or Danazol (n=120) group. Both treatment groups were evaluated after 3 months of treatment and efficacy was compared in terms of pain relief in patients of endometriosis. Results: In a total of 240 patients, the mean age was 28.30±4.76 years. The mean endometrial cyst size was 2.48±1.14 cm. At baseline, mean visual analog scale (VAS) score was recorded as 5.46±1.09 points in letrozole group and 5.28±1.01 points in danazol group (p=0.186). After three months of treatment, the mean VAS score was 2.94±1.96 points in letrozole group and 3.99±1.90 points in danazol group (p=0.002). Relief of symptoms was observed in 114 (47.5%) women and more patients reported relief of symptoms in letrozole group (65 patients) than the danazol group (49 patients) (p=0.039). Conclusion: Letrozole was more effective as compare to danazol in relief of pain in patients with endometriosis
Prevalence of Antibodies to Hepatitis B Core Antigen in Hepatitis B Surface Antigen Negative Healthy Blood Donors
Authors: Aijaz Razia , Siddiqui Humaira , Soomro Aqsa , Kanwal Marium , Hussain Waqar , Khalique Sumon
Published: December 2022

The screening of HBsAg has been the cornerstone in HBV research in various states and has greatly decreased but not eradicated TAHBV. Anti-HBc was supposed to be a good indicator of latent HBV infection in the window after HBsAg disappeared. Objective: To determine the prevalence of hepatitis B core antibodies in hepatitis B negative surface antigen healthy blood donors. Methods: This Cross-sectional study was held in the Medical Ward 7 of Jinnah Postgraduate Medical Center, Karachi from July 17, 2020 - January 16, 2021. A total of 147 healthy blood donors of both sexes, aged 17 to 65 years, who submitted an application for blood donation, were selected. The venous blood (5 ml) was gathered using aseptic technique. For 5 mints; Sera was centrifuged at 3000 rpm and separated. For the qualitative and quantitative detection of anti-HBc IgM, an ELISA test by DIA was performed. Results: Of the 147 patients, 81 (55.10%) were male, 66 (44.90%) were females with a M: F ratio of 1.3: 1. In this study; the patients age range was 17-65 years with 41.45 ± 8.97 years of mean age. The pervasiveness of anti-hepatitis B antibodies in healthy donors of blood who have negative surface antigen of hepatitis B virus was 6.12%. Conclusions: It was found that the pervasiveness of anti-hepatitis B antibodies in healthy donors of blood who have negative surface antigen of hepatitis B virus was 6.12%.
Prevalence and Phenotypic Detection of Carbapenem and Multi Drug Resistant of E. Coli in Urinary Tract Infection Patients in District Swat
Authors: Noor Uzma , Suliman Muhammad , Shams Husna , Sultan Amir , Hassan Khan Shah , Shazia .
Published: December 2022

Among prevalent infectious diseases, the most frequently occurring infections are the Urinary Tract Infections (UTIs) which predominantly occur in the community as well as in the hospital settings and are one of the main cause of morbidity and mortality worldwide. Objectives: To determine the frequency of MBL E. coli species in urine samples, antibiotic susceptibility pattern and the prevalence of MDR for E. coli. Methods: There were 200 urine samples obtained from Anwar clinical laboratory Saidu Sharif, District Swat, Pakistan. Samples of urine were obtained and then cultivated in selective media i.e. Cysteine Lactose Electrolyte Deficient Agar (CLED) and MacConkey Agar Plates. In traditional morphological and biochemical studies, isolates were identified. Results: Total 58 (29.6%) positive isolates were recovered from male while 116 (70.3%) urine specimens were positive from female patients, A total isolated bacteria were MBL positive including 36 (31.3%) isolated E. coli, Furthermore, in the total isolated species were identified as MDR positive in which 80 (69.5%) were E. coli, The most potent antibiotics found against bacteria were the highest for Meropenum (78.2%), Imepenum (73.9%), and Amikacin (26.0%) Cefuroxime (21.7%), respectively and Cefaclor (19.1%) were most sensitive while antibiotic mostly resistant showed. Conclusion: This study concludes that, the most prominent bacterial isolate in the urine samples was E. coli 115 (69.6%), Carbapenem resistance is frequently observed isolates of E. coli, which indicate that MBL phenotype should be regularly determined in clinical settings to prevent emerging Carbapenem resistance.
Relationship of Body Mass Index (BMI) with the Incidence of Inguinal Hernia
Authors: Hussain Zahoor , Ali Lashari Azad , Uddin Siraj , Ali Bijarani Farman , Hussain Memon Aijaz , Chandio Sadaf
Published: December 2022

The inguinal wall hernia is the communal hernia of the abdominal wall. It is a communal disorder that affects both males and females from the past long duration. Objective: To assess the incidence of unilateral or bilateral inguinal hernia with low body mass index (BMI) and normal BMI subjects. Methods: This study was performed in the Surgical unit 1 of Khairpur Medical College and civil Hospital Khairpur Mirs for one-year duration from July 2021 to June 2022. Using an appropriate non-probability sampling technique, this cross-sectional study was held at the surgical unit-1 of Khairpur Medical College and civil Hospital Khairpur Mirs. A total of 90 patients, 80 men and 10 women, were selected for the study. Inclusion criteria were defined as patients over 35 years of age with clinical signs such as reducible swelling in the groin area and clinical signs such as overweight and weight lifting.  Results: A total of 90 individuals were identified as having an inguinal hernia; their mean age was 26.18± 18.20 years old, and they have 62.78 ± 4.75 inches height. 65.85 ± 5.19 was the patients mean weight and 22.35 ± 3.26 kg/m2 was the mean BMI. BMI was low in 18 (20%) cases and normal in 72 (80%). Conclusion: According to our analysis, a significant number of inguinal hernias on either the right or left side had normal BMIs.
Antibiotic Resistance: An upcoming Pandemic
Authors: Mehboob Riffat
Published: December 2022

Antibiotics are medications that are used to both prevent and treat bacterial infections. Antibiotic resistance arises when bacteria adapt to the usage of antibiotics. Antibiotic resistance develops in bacteria rather than in humans or other animals. These germs can infect both humans and animals, and their infections are more difficult to treat than those caused by non-resistant bacteria. Antibiotic resistance causes greater mortality, longer hospital stays, and higher medical expenses. Our capacity to cure widespread infectious illnesses is being threatened by the emergence and worldwide dissemination of new resistance mechanisms. As antibiotics lose their potency, an increasing range of ailments, such as gonorrhoea, blood poisoning, pneumonia, and tuberculosis (TB), become difficult to treat and, in some cases, incurable. In every region of the globe, antibiotic resistance is increasing to dangerously high levels. It poses a serious danger to public health on a global scale, killing at least 1.27 million people and contributing to approximately 5 million deaths in 2019 [1]. More than 4.6 billion dollars a year is the projected cost to treat infections brought on by six multidrug-resistant pathogens that are often seen in healthcare settings. Escherichia coli is the pathogen that is most commonly reported in Pakistan (68.8% in 2018) [2, 3].

Antibiotic resistance jeopardizes advances in contemporary medicine. The main issues and concerns in Pakistan are a large number of surplus registered drugs (approximately 50,000), self-medication by more than 50% of the population, and a substantial number of quacks in the country. On average, each patient is given more than three drugs, and antibiotics are given to 70% of patients which is the highest number of prescriptions as compared to rest of the world. General practitioners (GPs) and public hospitals, which favor expensive broad-spectrum antibiotics, are more prone to prescribe these medications impulsively and without consideration [3]. Antibiotic abuse and misuse, as well as inefficient infection prevention and control, all contribute to the rapid spread of antibiotic resistance. Actions can be taken at all societal levels to mitigate the consequences and prevent resistance. Antibiotics should only be used as advised by a licensed healthcare provider. Doctors should only prescribe and give antibiotics when absolutely required, according to current recommendations. To address antibiotic resistance, the government must implement a comprehensive national action plan.
Diseño de un sistema de mantenimiento proactivo basado en la metodología RCM como propuesta para el mantenimiento de las plantas eléctricas tipo GPU del GANCA
Authors: Fren Mejía Alfonso , Batista Rodríguez Carlos Ramón , Howard Leal Víctor Andrés
Published: December 2022

En este artículo se desarrolló una propuesta de trabajo cuyo propósito fue diseñar una alternativa de mantenimiento basada en confiabilidad para brindar mayor disponibilidad operativa en las Unidades de alimentación de Potencia eléctrica a Aeronaves en Tierra (GPU), del Grupo Aeronaval del Caribe (GANCA) en la ciudad de Barranquilla. Como resultado de la aplicación de la metodología de Mantenimiento Centrado en Confiabilidad (RCM), se logró el desarrollo de matrices, análisis de criticidad, causas y consecuencias a partir de la recolección, clasificación y categorización de los equipos, subsistemas y sistemas hasta el nivel de componentes; esto con el fin de reconocer, anticipar y controlar los modos de falla a través de tareas de mantenimiento. Con esto, el GANCA tendrá una solución para el mantenimiento de sus GPU, que servirá de referencia para impactar en el aumento de la disponibilidad y con ello mejorar la efectividad de mantenimiento, que podrá ser usada como referencia para otros equipos de apoyo terrestre en la Aviación Naval de Colombia. Desde el punto de vista práctico, se recomienda usar el esquema propuesto en este trabajo.
Sürdürülebilir Ulaşım İle Lojistik Merkez Yer Seçimi
Authors: PAÇACI Burçin
Published: December 2022

Dünya ticaretinde rekabetin hızla artması ile daha sistemli ve hızlı taşımacılığa ihtiyaç duyulmaktadır. Yük taşımacılığında kilit rol oynayan lojistik merkezler, hızlı ve sistemli taşımacılığa cevap verebilmenin yanında sera gazı emisyon değerini azaltabilmekte, trafik tıkanıklığı ve çevre kirliliğini önleyerek çevreye daha duyarlı sürdürülebilir ulaşım sağlayabilmektedir. Bu çalışma ile yük taşımacılığında sürdürülebilir ulaşımı desteklemek amacıyla ulaşım modları arasında daha az sera gazı emisyon değeri olan demir yolu ve deniz yolu ulaşım modlarının ülkemizdeki lojistik merkezlerde daha aktif rol oynaması amaçlanmıştır. Bu bağlamda sürdürülebilir lojistiği sağlayarak lojistik merkez yer seçiminde optimum konumu bulmak için ülkemizde bulunan 51 adet demir yolu yük istasyonu ve 71 adet liman başkanlığının konumları Coğrafi Bilgi Sistemlerine aktarılarak alternatif iller elde edilmiştir. Lojistik alanında uzman kişilerin görüşleri ve literatür taraması doğrultusunda “Çevreye Duyarlılık”, “Güvenilirlik” ve “Riskler” kriterleri belirlenmiştir. Her il için ilgili kurumlardan alınan verilere göre AHP tekniği yardımıyla alternatif iller sıralanarak lojistik merkez yer seçimi için en uygun konum bulunmuştur.
Impact of Selected Operating Conditions on the Optical Properties of Polymer Shields
Authors: Ubowska Agnieszka , Zmuda Trzebiatowski Piotr
Published: December 2022

The optical properties of polymer barriers used as machine covers and eye protection are extremely important for vision quality and user safety. The article presents the influence of liquid chemical substances at room temperature on the transparency of poly(methyl methacrylate) shields. UV/VIS spectroscopy was used to assess the impact of liquid chemical substances on the polymer’s permeability to visible, ultraviolet and infrared radiations. The tests showed that the contact of the poly(methyl methacrylate) sheath with liquid chemicals influences the transmittance of the PMMA surface to a limited extent, without thereby reducing the harmful effects of radiation on humans.
Measuring the Impact of Oil Revenues on Iraq’s GDP for the Duration (2005-2020)
Authors: Mahmud Najmadin Sumaya
Published: December 2022

The oil sector has an important role in the Iraqi economy represented by its revenues, as oil exports constitute about 96% of the total exports on all macroeconomic variables, including national income, gross domestic product, foreign trade, investments in all its forms and its determination of economic development trends that depend on fluctuations in international oil prices in addition to the unexpected factors such as external shocks. Oil exports play an important role in the structure of foreign trade in oil countries, including Iraq, which faces many challenges that hinder the process of economic development, represented by the lack of capital prepared for investment and the lack of domestic savings. The controversy of the study lies in knowing whether the oil revenues contributed to increasing the gross domestic product and financing the general budget, that is, improving economic growth rates or not. The research aims primarily to achieve the validity of the hypothesis by shedding light on the reality of the oil sector in Iraq, the material, moral capabilities, and oil privileges to clarify the impact of the oil sector and its role in improving economic growth rates. Then, the research relied on the inductive approach in order to reach the objectives of the research by identifying the concept of the oil sector and its impact on achieving desirable economic growth rates using the standard quantitative method in measuring the impact of the oil sector on the gross domestic product in Iraq using the (Eview9) program. The benchmark indicates that the relationship between oil revenues and GDP is a direct relationship, and oil revenues are the main source for generating national income and GDP, as Iraq directly depends on oil revenues and thus the validity of the hypothesis was proven through the analytical side and the standard side, as oil revenues plays a major role in increasing the gross domestic product and thus improving the rate of economic growth.
Impact of Non-Oil Export on Economic Growth in Iraq: An Application of the Bound Test Approach
Authors: Omer Muhammad Hawnaz
Published: December 2022

The crucial role of non-oil exports in promoting job creations, investments, productions and even infrastructure improvements is well established in the literature, in Iraq, despite the abundant of non-oil resources, non-oil exports accounts for less than 10 percent of total export receipts. This paper aims to examine the impact of non-oil exports on economic growth in Iraq by employing the ARDL model to investigate the long and short-run effects of non-oil exports on Iraq’s GDP. To do so, the annual data of GDP, non-oil exports of manufacture, food and agricultural products, and exchange rates have been collected from World Trade Organization and World Bank from (2003- 2020). The results reveal a significant impact of non-oil exports on economic growth in both the long and short run. It’s recommended for governments and policymakers that promoting non-oil exports and diversifying Iraq’s economy is paramount for faster economic growth, greater job creation, and less economic volatility.
Assessing the Enabling Conditions for Translating Restoration Commitments to Restoration Actions: Case of Cameroon
Authors: Chia Eugene L. , Nsubuga Francis W. , Chirwa Paxie W.
Published: December 2022

Understanding governance and policy related conditions is relevant to determine what is needed to drive large-scale landscape restoration investments. Using Cameroon as a case study, this paper assessed the enabling conditions for large-scale forest restoration focusing on tree growing as the main practice. Descriptive statistics and correlation analysis were applied to understand trends in the opinions of 48 stakeholders sampled purposefully, including the review of forestry and land use related strategy and policy documents. Results indicated that stakeholders and strategy documents, strongly recognize the relevance of governance and policy related conditions to drive large-scale restoration. The trends in stakeholder insights revealed that the capacity of these conditions is currently weak and insufficient to enable large-scale restoration and progress towards improving these conditions have been very slow when compared to assessments made more than a decade ago. There is a need for a strong political will to improve these enabling conditions, though the technical arguments required to help guide and drive the political will are weak. The forest landscape restoration strategic framework needs to be revised and reinforced with appropriate and in-depth technical and operational orientations on how to improve each of the enabling conditions that will help achieve the large-scale restoration commitments in Cameroon.
The Impact of Quality Dimensions of Accounting Information System Success on the Effectiveness of During-Financial Crisis Management: The Mediating Role of System Usage in a Government Sector Context
Authors: Dalloul Mahmoud Hany M , Ibrahim Zuraeda binti , Urus Sharina Tajul
Published: December 2022

The primary purpose of this research is to explore the value of quality dimensions of accounting information systems (AIS) success, as represented by system quality (SQ), information quality (IQ) and service quality (SVQ), on the effectiveness of management during financial crises. This paper highlights the mediation role of system usage (SU) in those associations in the context of a government ministry. Descriptive analytical and quantitative approaches were adopted, using a questionnaire as the data collection instrument and selecting employees of the Palestinian Ministry of Finance as a population sample for the research. A total of 141 questionnaires were distributed, of which 105 were valid for statistical analysis. In the data analysis, the partial least squares (PLS) and structural equation modelling (SEM) techniques were adopted using SmartPLS software. The results indicate a direct significant effect between SQ, IQ, SVQ, and managing during financial crises in the research context. The mediation of SU in the influence between IQ, SQ, and managing during financial crises in the governmental context is clear. Conversely, this mediation was not demonstrated in the effect of SVQ. The research emphasizes the necessity of adopting high-quality AIS in terms of SQ, IQ and SVQ because of their critical role in enhancing management effectiveness during a financial crisis. The advancement and wider employment of AIS that have high-quality characteristics can improve management tasks during a financial crisis, increasing the ability to contain the crisis and reduce its broader repercussions.
Morinda citrifolia Linn. fruit extract mitigates heroin seeking behavior in mice
Authors: Pandy Vijayapandi , Khan Yasmin , Yarlagadda Durga , Tatinada Sri
Published: December 2022

Methanolic extract of Morinda citrifolia unripe fruit (MMC) was tested against heroin addiction using a mouse modified runway model of drug‑seeking. Habituation sessions were carried out for 10 min/d for 3 days. On day 0, the total run time of each mouse was noted (the start box to goal box) during the preconditioning test. This was followed by the conditioning session (30 min), in which the animals were conditioned with escalating doses of heroin hydrochloride (5, 10, 20, 40 and 40 mg/kg) for 5 days upon entry into the goal box. On day 6, the run time of each mouse, from start to goal box, was recorded during the post conditioning test. Extinction trials were performed for the next 5 days, in which no drug/saline was injected upon goal box entry.
On day 13, a priming dose of heroin (8 mg/kg) was given to reinstate drug seeking in the mice. MMC given as oral doses (1, 3 and 5 g/kg) dose‑dependently prolonged the run time to reach the goal box, indicating MMC attenuated heroin reinforcement. Moreover, MMC (5 g/kg) was found to reverse the heroin‑seeking on extinction trial 1 and 2. MMC was also found to reverse heroin‑induced reinstatement in mice. This study demonstrates that MMC attenuated heroin seeking at different phases of drug self‑administration in a mouse modified runway model.
Factors Affecting the Cyclone Preparedness Programme Volunteers’ Performance in Early Warning Dissemination in Emergency Response in Bangladesh
Authors: Chakma Swarnali , Hokugo Akihiko , Rahman Md Atikur
Published: December 2022

Millions of people living along coastal Bangladesh are at risk from cyclones, and timely dissemination and social acceptance of effective early warnings could significantly save their lives. In recent years, the Cyclone Preparedness Programme (CPP) volunteers have gained considerable popularity among local community as the most reliable source for early warning and emergency assistance for evacuation during coastal cyclones. The sustainability of the CPP is threatened not only by limited funding but also by the difficulty of attracting and retaining committed and efficient volunteers. The purpose of this study is to identify factors that affect the activities of Cyclone Preparedness Programme volunteers regarding early warning dissemination during emergency responses. The research design of this study integrated both qualitative and quantitative approaches. The questionnaires were complemented by face-to-face interviews and Focus Group Discussion with 177 residents of the Koyra and Ukhiya sub-districts (Upazila) to investigate the respondents’ responses to early warning information. In addition, a total of 23 CPP volunteers’ opinions were collected through a questionnaire survey, to identify the factors influencing CPP volunteering performance. The obtained results also show that both of the study-area communities did not properly understand the cyclone early warning signal system delivered by CPP volunteers. Approximately 49% of the community said that they could not interpret the warning message. The low level of community contact with CPP volunteers also hinders trust in warning messages and evacuation decisions. The findings also concluded that the factors related to the effectiveness of volunteering were found to be individual volunteer’s experience, training opportunities, lack of equipment and materials due to lack of budget, the social class of individual volunteers and in the absence of proper coordination. Maintainace of CPP volunteers engaged throughout the year is very challenging.

These limited engagement features affect the cyclone preparedness and early warning activities of CPP. The government needs to implement policies that enable the mobilization of adequate resources and awareness campaigns to be mobilized toward the volunteers.
Consensus of Local Knowledge on landslide Hazard in Depopulated Mountain Communities in Japan – A Case Study on Matsunoyama Village
Authors: Dasanayaka Uditha , Matsuda Yoko
Published: December 2022

Rural depopulation in mountain communities is now well acknowledged as one of the salient challenges faced by Japan which made them more susceptible to landslide disasters with intense weather conditions. The degradation of the traditional culture due to the rapid depopulation in mountainous areas leads to the permanent disappearance of the best local knowledge for landslide disasters. This study attempts to investigate the community’s landslide hazard knowledge. The research applied structural questionnaires and informal interviews for data collection. Firstly, the analysis has been conducted for identifying the main components in local knowledge on landslide disasters. Based on the component’s results, the questionnaire was developed to measure awareness on those components within the community. Finally, the cultural consensus modelling was utilized in discovering the cultural truths not in individual responses but the degree of sharing of these responses. The research outcomes suggest how the local knowledge-based practices and the consensus of local knowledge had improved the level of disaster adaptation among the community members. Moreover, the findings revealed the impact of depopulation and aging on the sustainability of the mountain community in a landslide disaster environment.
Dependencies between animal and environmental factors and behavioral problems in horses: a survey-based analysis
Authors: Budzyńska Monika , Janicka Wiktoria , Michalska Martyna , Kapustka Joanna
Published: December 2022

Undesirable and stereotypical behaviors may indicate abnormalities in the living environment of animals. They have a negative impact on the welfare of animals and hinder the handling and use thereof. Unfortunately, horse owners often fail to recognize the causes of behavioral problems in their animals. The aim of the study was to analyze the breeding conditions, type of use and individual traits of horses in relation to displaying undesirable and stereotypical behavior. The assessment was made based on 609 online questionnaires completed by horse owners from Poland (n=376), UK (n=145), USA and Canada (n=66), Australia and NZ (n=22). It has been shown that the undesirable behaviors are influenced by e.g. access to pastures, presence of other horses on paddocks and supply frequency of roughage. Problematic behaviors are particularly frequently displayed by animals with a lively temperament. Horses should be kept under conditions meeting their feeding, social and locomotor behavioral needs. The evaluation of their individual traits may help to assess the risk of developing abnormal behavior and thus, to prevent it. Raising the awareness of horse keepers and breeders of the causes of problem behaviors should be the key issue.
PENGELOLAAN POTENSI DESA DENGAN PEMANFAATAN TIK DAN TRANSFORMASI DIGITAL UNTUK PENINGKATAN UMKM DAN BUMDES DESA BOTUTONUO KECAMATAN KABILA BONE KAB BONE BOLANGO
Authors: Bonok Zainudin , Hidayat Iksan , Mohamad Yasin , Abdusammad Syahrir , Tolago Ade irawaty , Yasser Muhammad , Yusuf Taufiq Ismail
Published: December 2022

Kegiatan pengabdian masyarakat bagi tenaga pendidik didalam salah satu upaya untuk melaksanakan salah satu tugas sebagai pelaksanaan  pada salah satu tridarma perguruan tinggi)-salah satunya Pengabdian ini adalah suatu upaya Universitas Negeri Gorontalo agar supaya  terlaksananya Tridarma Perguruan Tinggi untuk memberikan sumbangsih ilmu pengetahuan dan teknologi kepada masyarakat.Berdasarkan hal ini, kami mengajukan usulan kegiatan Pengabdian di Kantor Desa Botutonuo  kec Kabila Bone Kab Bone Bolango dengan Tujuan Pengabdian ini adalah untuk memberikan Pengelolaan Potensi Desa dengan Pemanfaatan TIK dan Transformasi Digital untuk peningkatan UMKM dan BUMDes Desa Botutonuo kecamatan kabila bone kabupaten Bone Bolango ,Target luaran yang diharapkan dari kegitan ini adalah  1)  Masyarakat yang ada usaha dan UMKM  dan juga Aparat Desa  mampu dan memiliki  pengetahuan tentang Pemanfaatan TIK  skala Desa dengan adanya : Komputer, Internet, Telepon seluler sehingga  arus informasi semakin lancar 2) Mayarakat yang berwirausaha dan UMKM dan BUMDes  dan Aparat desa memiliki pengetahuan tentang perlunya analisis bisnis dan kelayakan usaha agar UMKM dan BUMDes  lebih baik,lebih luas sebarannya, lebih mandiri dan berdaya saing Studi kelayakan bisnis pada prinsipnya bisa digunakan antara lain:

a).   Untuk merintis usaha baru, misalnya untuk membuka toko, membangun pabrik, mendirikan perusahaan jasa, membuka usaha dagang dan lain sebagainya.

b).   Untuk mengembangkan usaha yang sudah ada, misalnya untuk menambah kapasitas pabrik, memperluas skala usaha, untuk mengganti peralatan/mesin, untuk menambah mesin baru dan lain sebagainya.

c).    Untuk memilih jenis usaha atau investasi/proyek yang paling menguntungkan, misalnya pilihan usaha dagang, pilihan usaha barang atau jasa, pabrikasi atau perakitan, dan sebagainya.

Adapun pihak yang memerlukan dan berkepentingan dengan studi kelayakan usaha diantaranya: (1) Pihak wirausaha (pemilik perusahaan) (2) Pihak Investor dan Penyandang Dana, (3) Pihak masyarakat dan Pemerintah

Studi kelayakan usaha dapat dilakukan melalui langkah-langkah sebagai berikut: (a) Tahap Penemuan ide atau Perumusan Gagasan, (b) Tahap Memformulasikan Tujuan dan  (c) Tahap Analisis
SOSIALISASI DALAM UPAYA MEWUJUDKAN DESA BERSIH NARKOBA
Authors: Hariana Hariana , Mardin Herinda , Lasalewo Trifandi
Published: December 2022

Upaya pencegahan terhadap bahaya penyalahgunaan narkoba perlu dilakukan dalam lingkungan masyarakat. Edukasi penyalahgunaan narkoba terhadap remaja dan masyarakat desa Botuwombato dan sekitarnya perlu mendapat perhatian pemerintah setempat. Melalui kegiatan KKN Tematik UNG tahun 2021, tim pendamping KKN bersama dengan mahasiswa KKN dari UNG melaksanakan kegiatan dalam bentuk sosialisasi terkait dengan penyalahgunaan narkoba di lingkungan masyarakat Desa Botuwombato. Kegiatan sosialisasi dilaksanakan pada tanggal 06 Oktober 2021 bertempat di kantor desa Botuwombato Kecamatan Kwandang Kabupaten Gorontalo. Manfaat dari sosialisasi ini bertujuan menambah wawasan dan edukasi masyarakat sekitar Desa Botuwombato terkait dengan jenis narkoba, dampak penggunaan narkoba, bentuk penanggulangan, serta keterkaitan hukum akibat pemakaian narkoba. Tim Pendamping kegiatan KKN UNG memotivasi masyarakat Desa Botuwombatu agar dapat melakukan gerakan preventif yang dimulai dari lingkungan keluarga hingga ke masyarakat luas agar terhindar dari bahaya narkoba. Luaran dari kegiatan sosialisasi adalah pembentukan sinergitas antara pemerintah setempat dan mayarakat dari Desa Botuwombatu dengan Badan Narkotika Nasional (BNN) yang berada di Kabupaten Gorontalo Utara. Pihak Badan Narkotika Nasional (BNN) membentuk tim Relawan Anti Narkoba di Desa Botuwombato. Pembentukan Relawan Anti Narkoba menjadikan masyarakat lebih memahami dan mengerti dampak hukum bagi penyalahgunaan narkoba.
PENGUATAN KOMPETENSI GURU DALAM IMPLEMENTASI BLENDED LEARNING
Authors: HIdayat Ikhsan , Bonok ZAINUDIN , Asmara Bambang Panji , Arafat Muhammad Yasser , Sarlin Muhammad
Published: December 2022

Teknologi telah menjadikan proses pembelajaran lebih fleksibel, lebih praktis, dan lebih efisien karena tidak tergantung hanya pada kegiatan tatap muka di kelas saja. melainkan juga di luar kelas, atau di luar jadwal pelajaran. Perubahan ini menjadi tantangan bagi para guru untuk berinovasi dalam mengajar dengan memanfaatkan teknologi dengan bijak. Proses belajar yang memadukan tatap muka dan online, yang disebut Blended Learning (BL), telah menjadi model platform pembelajaran yang banyak diimplementasikan di sekolah-sekolah dan perguruan tinggi karena hakikat BL yang luwes dan memberi kesempatan kepada siswa untuk belajar dari sumber belajar dan moda belajar yang bervariasi. Meningkatkan hasil dan minat belajar dibandingkan dengan metode pembelajaran yang hanya satu macam, blended learning mampu meningkatkan hasil dan minat belajar siswa. Hal itu karena metode belajar yang digunakan jauh lebih menarik dan menggunakan media pembelajaran yang menarik pula.
PEMANFAATAN LIMBAH CAIR TAHU DENGAN DOSIS BERBEDA TERHADAP PERTUMBUHAN Skeletonema costatum
Authors: Masrun Masrun , Hasim Hasim , Mulis Mulis
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pupuk limbah cair tahu terhadap pertumbuhan Skletonema costatum. Penelitian dilaksanakan pada tanggal 15 sampai 28 Februari 2021, bertempat di UPTD Balai Perikanan Budidaya Ikan Laut dan Payau (BPBLP), Lamu Kecamatan Tilamuta. Metode yang digunakan adalah eksperimen dengan Rancangan Acak Lengkap (RAL) dengan 4 Perlakuan yaitu A (limbah cair tahu 30 ml/l + pupuk silikat 1 mg/l), B (limbah cair tahu 40 ml/l + pupuk silikat 1 mg/l), C (limbah cair tahu 50 ml/l + pupuk silikat 1 mg/l), dan D (Kontrol) (NPK 3 mg/l + urea 8 mg/l + silika 1 mg/l) dan 3 Ulangan, sehingga total unit percobaan berjumlah 12 unit. Variabel yang diamati yaitu pertumbuhan kepadatan Skeletonema costatum. Data yang diperoleh dianalisis menggunakan Analysis of Variance (ANOVA) dengan aplikasi IBM SPSS 20. Hasil penelitian menunjukan bahwa pemanfaatan limbah cair tahu dengan dosis yang berbeda memberikan pengaruh sangat nyata terhadap pertumbuhan Skeletonema costatum. Dimana nilai Sig. < 0.05. Pertumbuhan kepadatan Skeletonema costatum yang terbaik terdapat pada perlakuan A (limbah cair tahu 30 ml/l + pupuk silikat 1 mg/l).
ANALISIS KAPASITAS PRODUKSI VCO (VIRGIN COCONUT OIL) MENGGUNAKAN METODE RCCP (ROUGH CUT CAPACITY PLANNING) DI PT. MILLENIUM AGROINDO SELEBES
Authors: Bersabie Rolando , Lasalewo Trifandi , Machmoed Buyung Rahmad
Published: December 2022

PT. Millenium Agroindo Selebes merupakan perusahaan yang bergerak di bidang pengolahan kelapa dimana produk yang dihasilkan merupakan VCO (Virgin Coconut Oil). Selama ini perusahaan hanya melakukan penambahan atau pengurangan jam kerja saat adanya lonjakan permintaan tanpa mempertimbangkan terlebih dahulu fasilitas atau sumber daya yang dimiliki secara efisien, sehingga menimbulkan ongkos produksi yang berlebih. Tujuan dari penelitian ini adalah membuat rencana produksi VCO dan mengetahui kelayakan kapasitas produksi VCO PT. Millenium Agroindo Selebes. Penelitian ini menggunakan metode RCCP (Rough Cut Capacity Planning). RCCP merupakan metode yang digunakan untuk mengukur kapasitas stasiun kerja sehingga dapat diketahui apakah suatu jadwal produksi memerlukan jam kerja lembur atau sub contract, prosedur ini dilakukan untuk memberi keyakinan bahwa jadwal induk produksi tidak melebihi kapasitas yang ada pada semua stasiun kerja yang dapat menghambat kelancaran proses produksi Hasil dari penelitian ini menunjukan bahwa beberapa stasiun kerja pada produksi VCO PT. Millenium Agroindo Selebes mengalami kekurangan kapasitas. Stasiun kerja yang terjadi kekurangan kapasitas yaitu Belt Juicer sebesar -23,53%, Screw Juicer sebesar -7,06% dan Tubular Centrifuge sebesar -11,18% yang mengakibatkan perusahaan belum dapat berproduksi secara optimal.
KONSEP SEMIOTIKA PADA BANGUNAN MASJID AGUNG BAITURRAHIM GORONTALO, KOTA GORONTALO
Authors: Abdullah Amalia Eka Putri , Heryati Heryati
Published: December 2022

Semiotika merupakan ilmu membaca tanda dalam memberikan pemaknaan pada arsitektur. Pemkanaan melalui bahasa simbol yang akan memberikan pesan tertentu bagi pengamat. Penelitian ini bertujuan untuk memahami bagaimana penerapan tanda berdasarkan semiotika Pierce: Ikon, Indeks, dan Simbol pada bangunan Masjid Agung Baiturrahim. Metode yang digunakan adalah kualitatif deskriptif. Penelitian dilakukan dengan mengamati bangunan Masjid Agung Baiturrahim secara detil untuk menemukan aspek fisik yang menjadi penanda dan memberikan makna pada arsitekturnya. Hasil penelitian menunjukkan bahwa Masjid Agung Baiturrahim termasuk bangunan yang menerapkan konsep Arsitektur Semiotika yang terbaca pada elemen bentuk bangunan, fasad, pintu utama, mihrab, menara, atap, dan pedestrian. Elemen-elemen ini teridentifikasi melalui penanda Ikon, Indeks, dan Simbol. Pembacaan semiotika pada bangunan Masjid Agung Baiturrahim menunjukkan adanya ekspresi nilai-nilai kearifan lokal yang menyusun Konsep Arsitekturnya.
Upgrading the IMAX theatre at London’s Science Museum
Authors: Young Claire
Published: December 2022

This article provides an overview of the recent refurbishment and upgrade of the IMAX cinema located in the Ronson Theatre at London's Science Museum, including discussion of the initial investigations of the existing structure.
Reuse, build less, build lean: low-carbon design for 22 Bishopsgate, London
Authors: Padilla Philipps Diego
Published: December 2022

22 Bishopsgate was erected on the site of an abandoned project, reusing 100% of the existing foundations from three previous buildings, and incorporating more than 50% of the basement built for its predecessor. This article describes the approach to reusing the existing foundations and basement, as well as the focus on material efficiency in designing the superstructure and transfer structures.
Cover to reinforcement – getting it right: product performance requirements
Authors: Shaw Chris
Published: December 2022

On the 20th anniversary of its publication, Chris Shaw explains how BS 7973:2001 solves the problem of failure to achieve the specified concrete cover to steel reinforcement. Part 1 of this article discusses product performance requirements for spacers and chairs.
Measuring carbon – a small practice perspective
Authors: Laidler Peter
Published: December 2022

In this article, Peter Laidler describes his small practice’s experience of responding to the climate emergency by seeking to minimise upfront carbon and maximise material utilisation in its structural designs, as well as encouraging retrofit and reuse. The practice has developed a simple carbon calculator in order to integrate embodied carbon calculations into standard design procedures.
Design solutions for efficient timber buildings
Authors: Walker James
Published: December 2022

This article offers some solutions to help structural engineers design efficient timber buildings.
Power stations, bridges and skyscrapers: forgotten figures in structural engineering history. Part 2: Florence Taylor and Mary Irvine - first women members of the Institution of Structural Engineers
Authors: Cobb Fiona
Published: December 2022

The 2020 James Sutherland History Lecture given by Steven Brindle covered the emergence of structural engineering as a profession over the last 200 years. This paper covers the same period but from a slightly different perspective, looking at some early women in structural engineering. The paper is in two parts. The first, by Nina Baker, provided some general context and an overview of some of the better known women engineers of this period. The second part, by Fiona Cobb, covers new research into two figures of particular interest to the Institution of Structural Engineers. For this, there are two candidates as ‘first woman’ of the Institution: Florence Taylor (1926) and Mary Irvine (1947) and they are of particular interest as we approach their Institution anniversaries. The centenary of Taylor’s membership will be in 2026 and the 75th anniversary of Irvine’s will be in 2022.
How to read an EPD: basics for the structural engineer
Authors: Lorenz Emily
Published: December 2022

Emily Lorenz provides a brief guide to environmental product declarations, enabling structural engineers to better understand the information these contain when making design decisions.
La contaminación acústica submarina: especial referencia al impacto sobre los cetáceos producido por los sónares de los buques de guerra
Authors: Franco García Miguel Ángel
Published: December 2022

Este artículo aborda la cuestión de la protección que diversas normas, nacionales e internacionales, dispensan a los animales marinos frente a la contaminación acústica de origen antropogénico. Se analiza, en particular, el régimen jurídico tuitivo de los cetáceos frente al ruido producido por los sónares de los buques de guerra.
Evaluasi Program Menjahit LKP Anita di Kota Serang
Authors: Yusriyah Wanda , Ravena Aliyah
Published: December 2022

Artikel ini merupakan hasil evaluasi yang dilakukan pada program pelatihan menjahit di LKP ANITA Kota Serang dengan menggunakan model evaluasi CIPP. Evaluasi dilakukan untuk mengetahui, mengukur ataupun menilai: 1) Context program yang meliputi kesesuaian antara kebutuhan peserta didik dengan pelatihan yang disediakan dan tercapai atau tidaknya tujuan LKP ANITA. 2) Input program yang meliputi meliputi komponen peserta didik, instruktur, kurikulum, materi pelatihan, pendanaan, sarana dan prasarana. 3) Process program yang meliputi seluruh kegiatan dan aktivitas peserta didik, instruktur, strategi pembelajaran dan partisipasi peserta didik selama proses pelatihan berlangsung. 4) Product program yang meliputi kesesuian kualitas produk dengan yang diharapkan penyelenggara, dampak dan manfaat yang dirasakan peserta didik setelah mengikuti program tersebut. Teknik pengumpulan data dilakukan dengan observasi, wawncara dan dokumentasi. Informan yang digunakan dianataranya yaitu penyelenggara, instruktur dan peserta didik. Hasil evaluasi menunjukan bahwa context program yang diselenggarakan LKP Anita sudah sesuai dengan kebutuhan peserta didik dan tujuan antara peserta didik dengan LKP Anita selaras. Input program yang dilakukan LKP ANITA sudah baik dan sesuai dengan apa yang diharapkan. Process selama pelatihan menjahit terlaksana dengan baik, lancara dan cukup efisien. Kualitas product, manfaat serta dampak yang dirasakan peserta didik sudah sesuai dengan apa yang diinginkan LKP ANITA dan peserta didik. Kesimpulan evaluasi Context, Input, Process dan product LKP ANITA sudah baik, hanya saja LKP ANITA kurang memaksimalkan sosialisasi program dan penggunaan papan tulis atau proyektor akan lebih membantu peserta didik dalam memahami materi perhitungan.
New Aspects in the Integration of MS Technologies in the Biopharmaceutical Industry
Authors: Candish Esme , Dykstra Andrew , Polozova Alla , Ren Da , Zhang Hao
Published: December 2022

In the past decade, advances in both separations and mass spectrometry (MS) technologies have enabled new, streamlined, and data-rich approaches to monitor product quality attributes and their relationship with process parameters throughout the lifecycle of therapeutic proteins. As we enter a new decade of technology and method development, MS-based approaches utilized in the biopharmaceutical industry are evolving further. In this mini-review, we explore key developments that could inspire and improve the future of therapeutic protein development.
ROLE OF CLOSE-LOOP SUPPLY CHAIN ON ACHIEVING TRIPLE BOTTOM LINE IN FMCG SECTOR OF MANUFACTURING INDUSTRY
Authors: SHAIKH M. JIYAD
Published: December 2022

The purpose of this study is to explore the role of close-loop supply chain in achieving triple bottom line approach in FMCG sector of manufacturing industry. To identify the strategies organizations implement for close-loop supply chain and the perception of supply chain professionals regarding close-loop supply chain and triple bottom line. This study highlights the strategies and initiative taken by the organization in order to achieve triple bottom line and the perception of the supply chain professional regarding the link between close-loop supply chain and triple bottom line (corporate profitability, consumer profitability and environmental sustainability). This study is based upon inductive approach which helps to generate a perception of the managers of FMCG manufacturers. This study identifies the significance of integration among the members of supply chain and emphasis on equal responsibility of every member towards environment.

In order to explore the perception of the managers and organizations in-depth interviews were taken through an interview protocol which consist of open ended questions. The interviews were taken from the different organizations of Karachi. Secondary data is also used by collecting data from past articles, websites, journals and research papers.

After content analysis of in-depth interviews, researcher came on conclusion that there is need to create awareness about the usage of recycled materials and triple bottom line among the corporate world. Also there is no proper guideline for the organizations to follow for the betterment of the environment. The concept of close-loop supply chain and triple bottom line of supply chain professionals of Karachi is vague. There must be proper enforcement by the concerned authorities on following the guideline provided by GRI (Global Resource Initiative).
EVALUATION OF ACHE ACTIVITY AND LIPID PEROXIDATION IN FRESHWATER TELEOST UPON EXPOSURE TO HERBICIDE
Authors: SINGH KALPANA , GARG VANDANA
Published: December 2022

In this study, the freshwater fish Channa punctatus was used to study the harmful effects of clomazone on AChE and LPO at three different doses and for four different exposure times. To determine the sublethal concentrations of clomazone, the LC50 of the herbicide was calculated. Based on the calculated LC50 value, three different concentrations were determined: high dose- 0.5 ppm, mild dose- 0.25 ppm, and low dose- 0.08 ppm. The fish were treated with these concentrations and the exposure period was 7, 14, 21, and 28 days respectively. The acetylcholinesterase activity and concentration of MDA were significantly decreased (p<0.05) and increased (p<0.05), respectively, upon higher concentration and also with the increase in exposure periods. The highest reduction of AChE was recorded in the liver, followed by the kidney and gill in all three concentrations. On the other hand, the MDA concentration was recorded highest in the kidney, followed by the liver and gills. Though, in the liver, the concentration of MDA is almost the same when exposed to concentrations of 0.5 and 0.25 ppm clomazone. Thus, our findings imply that AChE activity and lipid peroxidation may be potential indicators of environmental pollutants in aquatic systems.
DIGITALISASI PEMASARAN SERTA PENDAMPINGAN MANAJEMEN USAHA PADA UMKM ANGKRINGAN KMS DI TUMPANG KABUPATEN MALANG
Authors: Amiroh Iklila , Rahayu Dita Rahmi , Winarno Agung , Hermawan Agus
Published: December 2022

The development of MSMEs is increasingly rapid, not spared from increasingly fierce competition. The emergence of MSME competition if it is not balanced with adequate management, it will be difficult to develop and will be worse off being beaten by its competitors. Therefore digital marketing through social media and online marketplace platforms is urgently needed at this time. However, many MSME actors ignore digital marketing due to a lack of knowledge about technology. This also happened to the "Angkringan KMS" MSMEs located in Tumpang District, Malang Regency, which had not utilized digital technology in their business. Apart from not doing digital marketing, these MSMEs are also not good at financial management, as evidenced by the absence of financial records. The purpose of this research is that partners can develop because of digital marketing so that they can increase sales, partners can prepare financial reports properly, have a menu list design and logos for social media to attract and make it easier for consumers to buy products. This service research method is to carry out initial identification, analysis or planning, implementation and assistance, and evaluation. The results obtained from this activity are partners who understand digital marketing, simple financial reports, and design menu lists and logos for social media
ՆԱԶԻԿ ԱՎԱԳՅԱՆԻ ՀԻՇԱՏԱԿԻՆ / IN MEMORY OF NAZIK AVAGYAN
Authors: Avanesyan Lilia
Published: December 2022

IN MEMORY OF NAZIK AVAGYAN