bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular detection of Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus 2 and Hepatitis E Virus in oral fluid compared to detection in faeces and serum.
Authors: Plut Jan , Jamnikar-Ciglenecki Urska , Stukelj Marina
Published: November 2019

Background Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), Porcine Circovirus Type 2 (PCV2) and Hepatitis E virus (HEV) are common and economically important viral disease causative agents detected in pig oral fluid (OF), faeces and serum at some infection stages. The purpose of this study was to detect and compare PRRSV, PCV2 and HEV on six pig farms to determine which of the three sample types, OF, faeces or serum is appropriate for the diagnosis of these viruses in different pig categories. The following pig categories were included in the study: 5 weeks-old (w/o), 7 w/o, 9 w/o, 11 w/o weaners, fatteners and breeding sows. Pursuant to preliminary detection of each pathogen at the selected farms, OF samples, faeces, serum pools and 10 individual sera were tested with PCR for each age category. If any of the viruses were found in pools of faeces and OF, then faeces and OF from positive farms were tested separately for each pig category. The nucleic acid isolated from the samples was detected with RT-PCR, PCR and real-time RT-PCR for PRRSV, PCV2 and HEV respectively. Results PRRSV and HEV were detected on one farm and PCV2 on three others, positive results being more often obtained from the OF than from the faeces of the same animals. Testing of 10 individual sera samples from pigs from the same group of pigs was also performed, and detected the virus in individual sera and OF in the same pig category, with some exceptions: PRRSV was detected in the OF of fatteners but was absent in their sera; PCV2 was detected in sera but absent in group samples or vice-versa but OF sample , whereas HEV was detected in the OF of the youngest, 5w/o weaners and absent in sera of the same age group. Conclusions The primary finding of the study is that OF is a welfare-friendly, non-invasive and highly efficient matrix for pathogen detection, thus evidencing the utility of pig OF as a matrix in which each of the three viruses considered can be detected with the highest probability.
Telomere Length in Patients with Transfusion-Dependent Thalassemia
Authors: Nanthatanti Nithita , Tantiworawit Adisak , Piriyakhuntorn Pokpong , Rattanathammethee Thanawat , Hantrakool Sasinee , Chai-Adisaksopha Chatree , Rattarittamrong Eakarat , Norasetthada Lalita , Tuntiwechapikul Wirote , Fanhchaksai Kanda , Charoenkwan Pimlak , Kumfu Sirinart , Chattipakorn Nipon
Published: November 2019

Background: Thalassemia is a hereditary hemolytic anemia with a severity ranging from mild, non transfusion-dependent to severe chronic anemia requiring lifelong transfusion. Transfusional iron overload is a major complication in patients with transfusion-dependent thalassemia (TDT). Telomeres are sequences of nucleotides forming the end caps of chromosomes that act as a DNA repair system. Iron overload in thalassemia can cause increased oxidative stress which leads to cellular damage and senescence. This may result in telomere length shortening. The degree of telomere length shortening may reflect the severity of thalassemia.
Methods: This research aimed to study the telomere length in patients with TDT in comparison to non-thalassemic individuals and to identify the clinical and laboratory parameters that are associated with telomere length. We conducted a cross-sectional study in patients with TDT aged ³18 years. Telomere length was measured by real-time quantitative PCR.
Results: Sixty-five patients with TDT were enrolled onto the study. There were 37 female patients (54.4%). The median age was 27 (18-57) years, and mean pre-transfusion hemoglobin (Hb) was 7.1 (± 1.07) g/dL. The mean telomeric terminal restriction fragment length (TRFL) of patients with TDT and the controls was 6.11 (± 0.61) kb and 6.79 (± 0.84) kb, respectively (p <0.0001). There was a significant correlation between TRFL and age (p =0.0002), and Hb (p=0.044). There was no correlation of telomere length with other factors.
Conclusions: Our study showed that TDT patients had shorter telomere length compared with controls. Telomere shortening in TDT was an aging-dependent process and associated with lower hemoglobin level.
Content validation of the EORTC QLQ-C15-PAL with advanced cancer patients and health care professionals from palliative care services in Chile
Authors: Rojas-Concha Leslye , Hansen Maiken Bang , Petersen Morten Aagaard , Groenvold Mogens
Published: November 2019

Background: The assessment of patients’ quality of life (QOL) is essential when evaluating the outcome of palliative care; however, no instruments have been validated for measuring symptoms and QOL in patients receiving palliative care in Chile. We aimed to investigate the content validity of the EORTC Quality of Life Questionnaire Core 15 Palliative Care (QLQ-C15-PAL), replicating the methods used previously to shorten the EORTC Quality of Life Questionnaire Core 30 (QLQ-C30) for use among patients in palliative care.Methods: This cross-sectional study was conducted from October to November 2017 in four palliative care services. Patients with advanced cancer and health care professionals (HCPs) were invited to individual interviews to determine the relevance, appropriateness and relative importance of the 30 items of the QLQ-C30 for evaluating the outcome of palliative care, and whether relevant additional issues should be included. Results: A total of 48 patients and 35 HCPs participated. The most important dimensions selected were pain, physical functioning, sleeping difficulties, emotional functioning, nausea/vomiting, fatigue, and social functioning. Qualitative data identified important additional issues not covered by the questionnaire such as satisfaction with care, emotions and psychological support, as well as linguistic issues in the dyspnea and constipation items. Conclusions: The EORTC QLQ-C15-PAL showed good content validity in the assessment of symptoms and QOL of advanced cancer patients; therefore, we recommend the use of this questionnaire in palliative care in Chile. Dyspnea and constipation items were revised by the EORTC group. More research is needed to add a social dimension for a comprehensive assessment of patients’ QOL.
The impact of the duration of the palliative care period on cancer patients with regard to the use of hospital services and the place of death: a retrospective cohort study
Authors: Hirvonen Outi Maaria , Leskelä Riikka-Leena , Grönholm Lotta , Haltia Olli , Voltti Samuli , Tyynelä-Korhonen Kristiina , Rahko Eeva K. , Lehto Juho T. , Saarto Tiina
Published: November 2019

Background To avoid aggressive treatments at the end-of-life (EOL) and to provide palliative care (PC), physicians need to terminate futile anti-cancer treatments and define the palliative intention of the treatment in time, i.e. make the PC decision. This single center study assesses the impact of the PC decision and its timing on the use of hospital services at EOL and the place of death. Methods A randomly chosen cohort of 992 cancer patients treated in a tertiary hospital between Jan 2013 –Dec 2014, who were deceased by the end of 2014, were selected from the total number of 2737 identified from the hospital database. The PC decision and use of PC unit services were examined in relation to emergency department (ED) visits, hospital inpatient days and place of death. ResultsThe PC decision was defined for 82% of the patients and 37% visited a PC unit. The earlier the PC decision was made, the more often patients visited the PC unit (>180 days prior to death 72% and <14 days 10%). The number of ED visits and inpatient days were significantly highest for patients with no PC decision and lowest for patients with both a PC decision and a PC unit visit (60 days before death ED visits 1.3 vs 0.8 and inpatient days 9.9 vs 2.9 respectively, p<0.01). Patients with no PC decision died more often in secondary/tertiary hospitals (28% vs. 19% with a PC decision, and 6% with a decision and a visit to a PC unit). ConclusionsThe PC decision to initiate a palliative goal for the treatment had a distinct impact on the use of hospital services at the EOL. The earlier the decision the greater the effect. Contact with a PC unit further increased the likelihood of EOL care at primary care.
Does the medical insurance system really achieved the effect of poverty alleviation for the elderly in China? Characteristics of vulnerable groups and failure links
Authors: Ma Meiyan , Li Ye , Wang Nianshi , Wu Qunhong , Shan Linghan , Jiao Mingli , Fu Xuelian , Li Heng , Hao Yanhua , Yi Bin , Yin Hui , Tian Wanxin , Xia Qi , Ning Ning , Liang Libo , Wang Jiahui
Published: November 2019

Objective: We examined the physiological, household, and spatial agglomeration characteristics of the health poverty population in China. We identified weak links that affect the implementation of the medical insurance and further improve its effectiveness for health poverty alleviation. Methods: A national representative sample from the 2015 China Health and Pension Tracking Survey (CHARLS) was analyzed. The WHO recommended method was adopted to calculate catastrophic health expenditure (CHE) and impoverishment by medical expenses (IME). We created a binary indicator for IME as the outcome variable and applied the treatment-effect model to analyze the determinants of IME. Results： The incidence of IME was 7.2% of the overall population, compared to 20.3% of the sample households trapped in CHE. The incidence of IME enrolled in insurance schemes was 7.4% higher than that of uninsured families (4.8%). Economic level, living area, family size, age of household head, having hospitalized members, and participating in insurance were statistically significant for the occurrence of IME. Conclusion： The original poverty -promoting policies has not reached the maximum point of convergence with China ‘s current demand for health. The overlapped health vulnerabilities exacerbated the risk of poverty among the elderly and households with high health needs and utilization. In addition, the medical insurance schemes have proven to be insufficient for protection against economic burden of poor households. So, special health needs, age, and household capacity to pay should be comprehensively considered while strengthening the connection between the disease insurance scheme with supplementary insurance.
Melatonin attenuates vascular calcification by activating mitochondrial fusion and mitophagy via an AMPK/OPA1 signaling pathway
Authors: chen chenweiren , yang jia qi , liu fang , shen xue qin , sha yuan
Published: November 2019

Background: Mitochondrial fusion/mitophagy play a role in cardiovascular calcification. Melatonin has been shown to protect against cardiovascular disease. This study sought to explore whether melatonin attenuates vascular calcification by regulating mitochondrial fusion/mitophagy via an AMP activated protein kinase/ Optic atrophy 1 (AMPK/OPA1) signaling pathway.Methods: The effects of melatonin on vascular calcification were investigated in vascular smooth muscle cells (VSMCs). Calcium deposits were visualised by Alizarin red staining. Calcium content and alkaline phosphatase (ALP) activity were used to evaluate osteogenic differentiation. Western blots were used to measure expression of runt-related transcription factor 2 (Runx2), mitofusin 2 (Mfn2), mito-light chain 3 II (LC3II) and cleaved caspase3. Results: Melatonin markedly reduced calcium deposition and ALP activity. Runx2 and cleaved caspase3 were found to be down-regulated and Mfn2 or mito-LC3II was found to be enhanced in response to melatonin, together with a decrease in mitochondrial superoxide levels. Melatonin also maintained mitochondrial function and promoted mitochondrial fusion/mitophagy via OPA1 pathway. But OPA1 deletion abolished the protective effects of melatonin on VSMC calcification. Melatonin treatment significantly increased the p-AMPK and OPA1 protein expression. Treatment with compound C ablated the benefit observed with melatonin treatment. Conclusions: Melatonin protects VSMC against calcification by promoting mitochondrial fusion/mitophagy via AMPK/OPA1 pathway.
Anais XLVII Semana Odontológica UNIFAL-MG
Authors: Almeida Daniel Augusto de Faria , Paleari André Gustavo , Haddad Marcela Filié , Trindade Miler Lucas Santos da
Published: November 2019

EditorialCaro(a) Leitor(a),O curso de Odontologia da UNIFAL-MG é reconhecido por sua tradição dentro da Universidade e conta com ensino de excelência, com embasamento sólido e integrados na ciência odontológica em constante atualização.Para tal situação, eventos de forte impacto, carregados com o que há de mais recente no campo do ensino e pesquisa são de grande valia para a formação e/ou atualização profissional. E, é neste sentido que a Semana Científica Odontológica da UNIFAL-MG faz-se valer, completando sua 47ª edição em 2019, atendendo a cada edição um grande público entre acadêmicos a congressistas profissionais.Com o objetivo de divulgar os avanços científicos e tecnológicos para prevenção, diagnóstico e tratamento indicados atualmente na Odontologia, esta edição do evento contou com palestrantes que promoveram a discussão de temas relevantes e atuais para os acadêmicos e profissionais da área.Prof.Dr.Daniel Augusto de Faria AlmeidaCoordenador - XLVII Semana Odontológica UNIFAL-MG
Molecular Mechanisms Involved in the Antitumor Activity of Isolated Lectins from Marine Organisms: A Systematic Review
Authors: Ferreira Hugo Jefferson , de Almeida Evandro Moreira , da Silva Wildson Max Barbosa , Teixeira Edson Holanda , do Nascimento Neto Luiz Gonzaga
Published: November 2019

Introduction:

Tumor cells may present several molecular alterations that favor their malignancy, among which there is the expression of tumor-related antigens, such as truncated T-glycans, Thomsen-nouvelle, sialyl-Lewis X and sialyl Tn, which may help in the diagnosis and treatment using specific target molecules. Lectins are ubiquitous proteins capable of interacting with specific carbohydrates. Lectins isolated from marine organisms have important characteristics such as low immunogenicity and can bind to complex glycans compared to plant lectins.

Objective:

This work evaluated, through a systematic review, the molecular mechanisms of antitumor activity of lectins isolated from marine organisms. Methodology: The Pubmed, Lilacs, Science Direct, Wiley and Scopus databases were reviewed using the descriptors: marine lectin and cancer. Articles in English, published between January 2008 and December 2018, which proposed the molecular mechanisms of anticancer activity of lectins from marine organisms were eligible for the study.

Results:

17 articles were eligible. The lectins showed promising performance against cancer cells, presenting specific cytotoxicity for some types of malignant cells. The articles presented several lectins specific to different carbohydrates, modulating: pro and anti-apoptotic proteins, transcription factor E2F-1, via mitogen-activated protein kinase. In addition, exogenous lectin expression in cancer cells has been shown to be a promising way to treat cancer.

Conclusion:

This review showed the various studies that described the molecular mechanisms caused by marine lectins with antineoplastic potential. This knowledge is relevant for the development and use of the next generations of lectins isolated from marine organisms, supporting their potential in cancer treatment.
Nutritional Composition and Qualitative Phytochemical Analysis of Chia Seeds (Salvia hispanica L.) Grown in East Africa
Authors: Mihafu Fabian D. , Kiage Beatrice N. , Okoth Judith K. , Nyerere Andrew K.
Published: November 2019

Background:

Chia seed (Salvia hispanica L.) is becoming one of the most popular plantbased
foods that contain the greatest amount of nutrients particularly omega-3 fatty acid, α-linolenic
acid. It is therefore considered a functional food with pronounced health benefits.

Objective:

The purpose of this study was to determine the proximate composition, minerals, fatty acid
profiles and phytochemical contents of chia seeds grown in East Africa (Kenya and Uganda).

Methods:

Official methods of analysis, 2005 were adopted, minerals determined by Atomic absorption
spectrophotometer, phytochemicals were determined by standard methods and fatty acid profiles
were analyzed by Gas chromatography.

Results:

Proximate composition indicated high contents of protein, fat and fiber. The fatty acid profiles
revealed great amounts of α-linolenic acid (45.29-56.99%) followed by linoleic acid (15.9-
20.28%) and oleic acid (6.88-11.58%). However, the difference in the content of α-linolenic acid between
samples was not significant (p = 0.7391). Mineral determination (mg/100g) showed high contents
of potassium (492.96-862.98), phosphorous (486.45-569.45), calcium (297.47-429.09) and
magnesium (192.22-202.97) while considerable amount was observed for iron, zinc, manganese, and
copper. There was a significant difference (p = 0.0001) in mineral content between black chia Molo
and white chia Bukembo with the exception of phosphorus.

Conclusion:

Both black and white chia seeds grown in East Africa, observed to have high amounts
of α-linolenic acid, proteins, fats, fiber, and minerals. These findings support the evidence that chia is
rich in nutrients that are beneficial to human health. Therefore, we suggest its incorporation in diets
as a healthy food ingredient.
Prevalence and Predictors of Self-Medication Practices in India: A Systematic Literature Review and Meta-Analysis
Authors: Rashid Muhammed , Chhabra Manik , Kashyap Ananth , Undela Krishna , Gudi Sai K.
Published: November 2019

Background:

Self-Medication (SM) is a practice of using medications to treat selfdiagnosed
symptoms without a legitimate prescription by a health care professional. Alongside
posing a burden on a patient, SM practices are associated with certain unfavourable health conditions
such as drug-resistance, adverse effects, drug-interactions, including death.

Objective:

To systematically review and quantify the prevalence of SM practices and its associated
factors in India.

Methodology:

A comprehensive systematic search was performed using scientific databases such as
PubMed and Cochrane library for the peer-reviewed research articles that were conducted in India
without any language and date restrictions. Studies which were cross-sectional by design and assessing
the prevalence and predictors of SM practices in India were considered for the review, and
all the relevant articles were screened for their eligibility.

Results:

Of 248 articles, a total of 17 articles comprising of 10,248 participants were included in the
meta-analysis. Overall, the mean prevalence of SM practices in India was observed to be 53.57%.
Familiarity with the medication appears to be a major reason to practice SM (PR: 30.45; 95%
Confidence Interval [CI]: 17.08-43.82; 6 studies), and the practice was noticed more among
individuals from a middle-lower class family with a prevalence rate of 26.31 (95%CI: 2.02-50.60;
P<0.0001). Minor ailments were the primary reason for practicing SM (PR: 42.46; 95%CI: 21.87-
63.06), among which headache was the most commonly reported (PR: 41.53; 95%CI: 18.05-65.02).

Conclusion:

Self-medication practices are quite frequent in India. While NSAIDs and anti-allergens
are the most frequently utilized self-medicated drugs used for headache and cold and cough.
The Atrial Fibrillation Health Literacy Information Technology Trial: Pilot Trial of a Mobile Health App for Atrial Fibrillation (Preprint)
Authors: Guhl Emily , Althouse Andrew D , Pusateri Alexandra M , Kimani Everlyne , Paasche-Orlow Michael K , Bickmore Timothy W , Magnani Jared W
Published: November 2019

BACKGROUND

Atrial fibrillation (AF) is a common arrhythmia that adversely affects health-related quality of life (HRQoL). We conducted a pilot trial of individuals with AF using a smartphone to provide a relational agent as well as rhythm monitoring. We employed our pilot to measure acceptability and adherence and to assess its effectiveness in improving HRQoL and adherence.

OBJECTIVE

This study aims to measure acceptability and adherence and to assess its effectiveness to improve HRQoL and adherence.

METHODS

Participants were recruited from ambulatory clinics and randomized to a 30-day intervention or usual care. We collected baseline characteristics and conducted baseline and 30-day assessments of HRQoL using the Atrial Fibrillation Effect on Quality of Life (AFEQT) measure and self-reported adherence to anticoagulation. The intervention consisted of a smartphone-based relational agent, which simulates face-to-face counseling and delivered content on AF education, adherence, and symptom monitoring with prompted rhythm monitoring. We compared differences in AFEQT and adherence at 30 days, adjusted for baseline values. We quantified participants’ use and acceptability of the intervention.

RESULTS

A total of 120 participants were recruited and randomized (59 to control and 61 to intervention) to the pilot trial (mean age 72.1 years, SD 9.10; 62/120, 51.7% women). The control group had a 95% follow-up, and the intervention group had a 93% follow-up. The intervention group demonstrated significantly higher improvement in total AFEQT scores (adjusted mean difference 4.5; 95% CI 0.6-8.3; P=.03) and in daily activity (adjusted mean difference 7.1; 95% CI 1.8-12.4; P=.009) compared with the control between baseline and 30 days. The intervention group showed significantly improved self-reported adherence to anticoagulation therapy at 30 days (intervention 3.5%; control 23.2%; adjusted difference 16.6%; 95% CI 2.8%-30.4%; P<.001). Qualitative assessments of acceptability identified that participants found the relational agent useful, informative, and trustworthy.

CONCLUSIONS

Individuals randomized to a 30-day smartphone intervention with a relational agent and rhythm monitoring showed significant improvement in HRQoL and adherence. Participants had favorable acceptability of the intervention with both objective use and qualitative assessments of acceptability.
Assessment of Patient Satisfaction With Dermatology Clinics According to Clinic Type: Mixed Methods Study (Preprint)
Authors: Costigan Jennifer , Feldman Sue S , Lemak Mark
Published: November 2019

BACKGROUND

Consumer Assessment of Healthcare Providers and Systems (CAHPS) survey responses are considered significant indicators of the quality of care and patient satisfaction. There is a pressing need to improve patient satisfaction rates as CAHPS survey responses are considered when determining the amount a facility will be reimbursed by the Centers of Medicare and Medicaid each year. Low overall CAHPS scores for an academic medical center’s dermatology clinics were anecdotally attributed to clinic type. However, it was unclear whether clinic type was contributing to the low scores or whether there were other factors.

OBJECTIVE

This study aimed to determine where the efforts of patient satisfaction improvement should be focused for two different types of dermatology clinics (private and rapid access clinics).

METHODS

This study used a concurrent mixed methods design. Secondary data derived from the University of Alabama at Birmingham Hospital’s Press Ganey website were analyzed for clinic type comparisons and unstructured data were qualitatively analyzed to further enrich the quantitative findings. The University of Alabama at Birmingham Hospital is an academic medical center. The data were analyzed to determine the contributors responsible for each clinic not meeting national benchmarks. Thereafter, a review of these contributing factors was further performed to assess the difference in CAHPS scores between the private and rapid access clinics to determine if clinic type was a contributing factor to the overall scores.

RESULTS

The data sample included 821 responses from May 2017 to May 2018. Overall, when both private clinics and rapid access clinics were viewed collectively, majority of the patients reported stewardship of patient resources as the most poorly rated factor (367/549, 66.8%) and physician communication quality as the most positively rated factor (581/638, 91.0%). However, when private clinics and rapid access clinics were viewed individually, rapid access clinics contributed slightly to the overall lower dermatology scores at the academic medical center.

CONCLUSIONS

This study determined that different factors were responsible for lower CAHPS scores for the two different dermatology clinics. Some of the contributing factors were associated with the mission of the clinic. It was suspected that the mission had not been properly communicated to patients, leading to misaligned expectations of care at each clinic.
Anomalías del Poder Político en España y Algunas Propuestas para su Estudio
Authors: Fishman Robert M.
Published: November 2019

El estudio de la relación entre los representantes electos y la ciudadanía, y la teorización del poder político en España, requieren muchos tipos de investigación.
El estudio de las propias élites ofrece una aportación clave, una piedra angular, para la construcción de una visión global del tema pero también hay que contextualizar la actuación de las élites y estudiar sus interacciones con realidades que se centran fuera del mundo del poder. La relación por un lado entre los movimientos de protesta y el poder y por otro lado entre los líderes políticos y redes sociales más amplias es de una importancia considerable. Las complejidades del poder político en España incluyen varias anomalías relacionadas con la historia y sus legados culturales. Como consecuencia, muchas veces el poder se ha caracterizado por tendencias jerárquicas y poco incluyentes a pesar del carácter democrático del sistema.
Recursos y dilemas de la innovación social: un concepto problemático
Authors: Gurrutxaga Abad Ander , Galarraga Ezponda Auxkin
Published: November 2019

La tesis principal es que el concepto de innovación social está afectado por muchas indefiniciones que derivan de las controversias irresueltas que acompañan a su éxito. Está de moda y corre peligro de que se transforme en el “recurso para todo”, como si fuese el antídoto al que se recurre ante cualquier situación. En estos casos, el espacio puede estar ocupado por una retórica vacía de contenido, como si el papel de concepto contenedor rebajase las posibilidades teóricas, empíricas y analíticas del concepto. La salvación del concepto está en el regreso a la investigación social, a las metodologías y marcos analíticos que proporciona la teoría social y a la verificación empírica de todo aquello que dice ser y proporcionar. Para ello, resulta trascendente que se aborden un conjunto de controversias irresueltas que actualmente emergen en los debates sobre la innovación social.
Time Perspective in Patients with Affective Disorders: Review of Scientific Research
Authors: Zakharova Anna Yu , Trusova Anna V
Published: November 2019

The article presents the results of the theoretical analysis of the Russian and international studies devoted to the phenomenon of the time perspective of the personality. The time perspective is an extremely relevant research topic, and at the same time, a littlestudied area of psychological and psychiatric science. The history of the term is brieﬂy described, the main approaches to the deﬁnition of the concept are considered, the important properties and characteristics of the time perspective of the individual are determined. In this article, the features of the time perspective of a personality are considered with regard to anxiety and depression, important manifestations of aﬀective disorders; the properties of the temporal perspective are considered in the context of manifestations of anxiety and depression in patients with aﬀective disorders. The connection of the depressive episodes and the subjective attitude to the past, present, and future is marked, the role of dysfunctional time perspective in the context of depressive and anxious experiences is emphasized. The inﬂuence of subjective perception of time, especially future, on the increasing anxiety is reﬂected. Some foreign and domestic studies of the time perspective in patients with aﬀective disorders are considered and analyzed. We found some diﬀerences in subjective perception of time and time perspective in patients with anxious and depressive manifestations: the speed of time in depressed patients is slowed down, in anxious patients it is accelerated; as for the attitude to the past, present, and future, in patients with severe depressive manifestations there is a pessimistic attitude to the events of the future and ﬁxation on the events of the past.
The concept of social identity: Basic research approaches
Authors: Podvoyskiy D G , Soleimani S
Published: November 2019

Identity is one of the most complex and multidimensional terms of social sciences and humanities, which attracts attention of many intellectuals and researchers. We are social beings; thus, we have social identities. Our social life is impossible without a framework and basis for developing social and individual identities - without them no one can build meaningful or consistent relationships with other people. Social identity as the basis for identifying socially significant “similarities” and “differences” between individual and collective actors allows for continuous communication and sustainable interaction in the community. Explanations of social identity and factors influencing its cannot be limited to any theory or scientific school. Thus, the authors study the concept of social identity as defined by theories of macro- and micro-levels, and also by theories of social order and integration. The article starts with the macro-sociology theorists E. Durkheim and M. Castells and considers such concepts as “mechanical solidarity”, “organic solidarity”, “legitimizing identity”, “resistance identity” and “project identity”. The authors consider the views of representatives of the symbolic interactionism focusing on the concepts of “self” and “mind”, primarily in the theory of G.H. Mead; the ideas of Ch.H. Cooley based on the concepts of “looking-glass self” and “primary group”; the works of M. Rosenberg devoted to “self-concept”; the theories of H. Tajfel and A. Giddens describing identity and its varieties; and, finally, the views of P. Bourdieu and R. Jenkins. The authors conduct a kind of the preliminary comparison of the mentioned approaches to identify the features of their theoretical argumentation and the role of ‘identity’ in the theory of social order and theoretical-methodological dilemma ‘subject-structure’.
Lexical Peculiarities of the Modern Spanish Language of Guatemala
Authors: Kotenyatkina Irina B
Published: November 2019

Despite the fact that Russian linguists are actively exploring the peculiarities of the implementation of language means in Latin American countries, the Spanish language of Guatemala has not yet been the object of analysis in terms of the variation of lexical units. This article examines the lexical units used in the Guatemalan national variety of the Spanish language through the prism of modern lexical semantics, using the current common approaches and methods of the linguistics discipline. The peculiarities of the Guatemalan national variety of the Spanish language are demonstrated, such as: high-frequency common Spanish units that have undergone semantic changes; prevailing terms and idioms that are unusual for Spain; many innovations of both Guatemalan and Mexican origin are used; a large number of loanwords from indigenous languages; and diminutives are widely used. Finally, it is concluded that the revealed and studied peculiarities of the Spanish language of Guatemala determine the need to study it not only for developing philological knowledge but also, to a large extent, for meeting the practical needs of the modern society.
World fish market: current trends, state and prospects
Authors: Andronova Inna V , Yakimovich Elena A
Published: November 2019

The article analyzes the state of the world fish market, problems and prospects for its development in the context of current trends in the world economy. The authors emphasize the importance of the space allocated to the world fish market in solving global problems of our time, such as fighting hunger, ensuring food security, sustainable development, etc. The article presents the current state of world fishing and fish farming, the main producers and exporters, Russia’s place in this market. Reflected issues related to the role of developing countries in this sector of the economy. Conclusions are drawn about the problems and prospects of the world fish market from the point of view of the sustainable development of the world community and the growth of consumption of this food product by the population of the planet.
PEMBELAJARAN PENDIDIKAN AGAMA ISLAM BAGI ANAK USIA DINI
Authors: M. Ali Mahdi
Published: November 2019

This study examines the teaching of Islamic Religious Education (PAI) for Young Children at Pocut Baren Kindergarten Padang Tiji in the District of Pidie by analyzing learning activities, from the perspectives of curriculum and teaching materials as well as planning and the evaluation system. We utilize a descriptive-analytic approach to field research and look at a variety of literature relevant to teaching religion to young children as a theoretical foundation for our research.The review of school document, field observations, and interviews with the head of the kindergarten and teachers are an integral part of our analytical approach. Our study finds that the teachers of this kindergarten understand the curriculum and have proficiently designed the study plans even though their implementation are at times isolated from the already-designed daily and weekly sketches (SKH and SKM).Furthermore, the evaluation of Islamic religious education in this school is conducted daily and semi-annually (every semester) and the results of both tests indicate the overall progress and achievement of pupils. All of this illustrates that the implementation of Islamic religious education at Pocut Baren Kindergarten Padang Tiji has proceeded adequately for the purpose of achieving educational objectives stated in the curriculum. Yet, it still needs the principalâ€™s and teachersâ€™ further innovation and creativity, so that the teaching and learning processes become richer and are in accordance with the development of scientific progress and the dynamics of the new era.
The effects of ozone therapy on extremity ischemia-reperfusion injury in a rabbit model
Authors: KAYMAZ Burak , COBAN Ganime , GOKSEL Ferdi , TOMAN Huseyin , GOLGE Umut Hatay , KOMURCU Erkam
Published: November 2019

Introduction: Ischemia is reversible or
irreversible cell/tissue damage that is secondary to insufficient blood flow to
tissues or organs. Ischemia causes many metabolic and structural changes at the
cellular level. Ozone therapy is often used as an antioxidant remedy. This
study aimed to investigate the effects of ozone therapy on extremity
ischemia-reperfusion (IR) injury.

Methods: Twenty-four New Zealand
White (NZW) rabbits were randomly allocated into three groups. Each group
consisted of eight rabbits. Group I was the control group, Group II was the
ischemia group, and Group III, the ozone group. 
Femoral arteries of the right legs were dissected, and femoral arterial
occlusion was performed in Group II and III. 
Hematological and histopathological evaluation was performed in all
groups.

Results: The levels of total
antioxidant status (TAS) after the surgical procedure was higher in the ozone
group compared to the ischemia group (p=0.036). In addition, the levels of
malondialdehyde (MDA) after the surgical procedure were lower in the ozone
group compared to the ischemia group but not statistically significant
(p=0.093). The control and ozone groups were histopathologically similar.

Conclusions: Ozone therapy may be used
as an alternative treatment modality with its anti-inflammatory and antioxidant
effects for the treatment of extremity IR injury.
HIPERIDROSE E O USO DA TOXINA BOTULÍNICA COMO TRATAMENTO: REVISÃO BIBLIOGRÁFICA
Authors: Hagemann Daniela , Sinigaglia Giovana
Published: November 2019

Introdução: A hiperidrose é uma patologia caracterizada pelo suor excessivo, através do aumento das atividades das glândulas sudoríparas distribuídas pelo corpo, é a grande responsável pela hiperprodução de suor. Pode ser classificada como primária ou secundária; localizada ou generalizada. A hiperidrose atinge cerca de 3% da população, envolvendo jovens e adultos inicialmente na faixa etária dos 18 anos, com a incidência de homens e mulheres. De etiologia desconhecida associa-se a fatores emocionais, hereditários, ocupacionais e até mesmo sociais. Assim atividades diárias como um aperto de mãos podem causar desconforto aos pacientes. Dentre os tratamentos refere-se os nãos invasivos como antiperspirantes, medicamentos e os invasivos (cirúrgicos) como a simpatectomia torácica e lipossucção. Atualmente a utilização da toxina botulínica tem se mostrado eficaz na utilização como tratamento da hiperidrose. Métodos: O objetivo deste estudo é realizar a revisão bibliográfica de artigos encontrados de 2009 a 2019 com a utilização da toxina botulínica como forma de tratamento para a hiperidrose. Resultados: A toxina botulínica é uma inovação, bacilo gram-positivo, anaeróbico, tem sido muito utilizada no tratamento estético e mais recentemente no tratamento terapêutico de diversas patologias. Seu mecanismo de ação bloqueia a liberação do neurotransmissores acetilcolina, ou seja, transmissão sináptica ocasionando a cessação temporária das glândulas sudoríparas. O efeito foi constatado a partir da segunda aplicação da toxina botulínica e as doses de reforço para o tratamento foram de pequenas proporções, o efeito terapêutico teve duração média de 7 meses a 1 ano. Como desvantagens temos a dor no local da aplicação (múltiplas injeções) e o alto custo. Conclusão: A toxina botulínica mostrou-se eficaz no tratamento da hiperidrose e que não apresenta riscos aos pacientes contribuindo beneficamente a qualidade de vida dos mesmos.
ANALISA PRODUKTIVITAS DENGAN MENGGUNAKAN MODEL PENGUKURAN THE AMERICAN PRODUCTIVITY CENTER (APC) PADA PRODUK ALUMUNIUM SHEET DAN ALUMUNIUM FOIL
Authors: Beatrix Meike , Dewi Anis Anisah
Published: November 2019

Untuk meningkatkan volume penjualan dan keuntungan, maka perusahaan perlu memantau kinerja perusahaan secara keseluruhan, bukan hanya berdasarkan tingkat profitabilitas namun juga berdasarkan tingkat produktivitas. Produktivitas merupakan perbandingan antara output yang dihasilkan dan input yang digunakan. Penelitian ini bertujuan untuk mengetahui berapa besar tingkat produktivitas yang telah dicapai oleh perusahaan dengan menentukan indeks produktivitas, indeks profitabilitas dan indeks perbaikan harga dengan menggunakan model pengukuran The American Productivity Center (APC). Indeks produktivitas total yang diperoleh pada periode 2017 yaitu 114,252% dengan  indeks produktivitas input tenaga kerja, material, energi dan modal masing-masing pada periode 2017 yaitu 116,166%, 113,168%, 120,808%, 115,523%. Indeks profitabilitas total yang diperoleh pada periode 2017 yaitu 110,766% dengan indeks profitabilitas input tenaga kerja, material, energi dan modal masing-masing pada periode 2017 yaitu 128,903%, 103,246%, 129,615%, 125,563%. Indeks perbaikan harga dari tahun 2016 ke tahun 2017 diperoleh indeks perbaikan harga tertinggi pada input tenaga kerja yaitu 1,110% dan indeks perbaikan harga terendah pada input material yaitu 0,912%, indeks perbaikan harga energi dan modal masing-masing yaitu 1,073% dan 1,087%. Besar kecilnya indeks perbaikan harga dipengaruhi oleh biaya input yang digunakan untuk menghasilkan sejumlah output.
El cuento como estrategia didáctica para fortalecer las competencias de lectura y escritura en los estudiantes de los grados sexto y séptimo de un colegio del municipio de Cúcuta
Authors: Quintero-Sanabria Edixon Alfonso , Prado-Cárdenas Yuddy Clovet
Published: November 2019

Antecedentes: se tienen en cuenta diferentes proyectos como base teórica para la realización de este proyecto donde intervienen aspectos como las estrategias en el fortalecimiento de la lectura y la escritura de los estudiantes del mundo, enfatizando en Colombia y Norte de Santander. Objetivos: Se desarrollaron las habilidades lectoescrituras en los estudiantes del grado séptimo de un colegio de Cúcuta, mediante la estrategia didáctica Echémonos un cuento, haciendo hincapié en la escritura de cuentos a partir de diferentes actividades, diseñando diferentes estrategias didácticas y aplicándolas. Métodos: se partió de una etapa de diagnóstico donde se logró establecer que los estudiantes en mención presentaban serias falencias en aspectos de lectoescritura, lo cual se evidencia en su rendimiento académico y en las pruebas internas y externas (SABER) que estos presentan periódicamente. Resultados: como respuesta a dichas dificultades, se diseñaron y aplicaron actividades didácticas tomando como base el cuento, lo cual resultó ser una excelente herramienta didáctica, toda vez que se logró una activa participación de los estudiantes y una notoria mejoría en la interpretación producción y difusión del discurso de los estudiantes, tanto en la parte oral como escrita. Conclusión: Respecto al mejoramiento del desempeño académico, se debe aclarar que esto es un proceso que se ha de medir progresivamente, sin embargo, se empiezan desde ya a evidenciar, unos resultados muy satisfactorios y que, claramente, se verán evidenciados en futuras pruebas externas que presenten los estudiantes.
Hacia una concepción pragmatista de la educación estética y de la crítica de arte en la perspectiva de John Dewey
Authors: Rueda Leopoldo
Published: November 2019

En este trabajo, nos proponemos indagar en qué sentido(s) puede serentendida una educación estética en la teoría deweyana, lo que nos llevará a revisar las concepciones naturalistas de educación, arte y crítica. Finalizaremos señalando los diversos modos en que puede comprenderse que el arte educa y cuáles son los desafíos a afrontar ante una propuesta de estas características.Palabras clave: pragmatismo, educación estética, arte.
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE GROUP INVESTIGATION BERBANTUAN MEDIA VIRTUAL LABORATORY TERHADAP HASIL BELAJAR IPA SISWA
Authors: Halimah Nur , Suma Ketut , Sarini Putri
Published: November 2019

Penelitian ini bertujuan untuk mendeskripsikan dan menjelaskan perbedaan hasil belajar IPA antara siswa yang dibelajarkan dengan model pembelajaran kooperatif tipe Group Investigation berbantuan media virtual laboratory dan model pembelajaran Direct Instruction. Penelitian ini merupakan penelitian eksperimen semu (quasi experiment) dengan rancangan non-equivalent pretest-posttest control group design. Populasi penelitian ini adalah seluruh siswa kelas VIII MTs Negeri 2 Buleleng tahun ajaran 2017/2018 yang berjumlah 80 siswa yang tersebar ke dalam 4 kelas. Pengambilan sampel dilakukan dengan teknik simple random sampling untuk memperoleh 2 kelas sebagai kelas eksperimen dan 2 kelas sebagai kelas kontrol. Data hasil belajar dikumpulkan melalui tes pilihan ganda diperluas sebanyak 20 item, dengan reliabilitas sebesar 0,883. Data dianalisis menggunakan statistik deskriptif dan Anakova satu jalur dengan taraf signifikansi 5%, kemudian dilakukan uji lanjut yaitu uji signifikansi skor rata-rata antar kelompok yang menggunakan Least Significant Difference (LSD). Hasil penelitian menunjukkan terdapat perbedaan hasil belajar IPA antara siswa yang dibelajarkan dengan model pembelajaran Group Investigation berbantuan media virtual laboratory dan model pembelajaran Direct Instruction. Rata-rata skor hasil belajar IPA antara siswa yang belajar dengan model pembelajaran Group Investigation berbantuan media virtual laboratory lebih tinggi dibandingkan dengan rata-rata skor hasil belajar IPA yang belajar dengan model pembelajaran Direct Instruction.
CREATIVE INDUSTRY DEVELOPMENT BASED ON ENTREPRENEURSHIP TRAINING IN DEVELOPING LOCAL ECONOMY IN PAREPARE CITY
Authors: Rakib Muhammad , Yunus Muchtar , Amin Nur
Published: November 2019

This study aims to determine the development of creative industries, the usefulness of the implementation of entrepreneurship training, the factors that support and inhibit, and formulate a creative industry development strategy based on entrepreneurship training in an effort to develop local economic areas in the city of Parepare. This research is a type of evaluation research using a qualitative approach. This research was conducted in Parepare Town of South Sulawesi. The subjects of the study were the participants of entrepreneurship training in Kota Parepare, and the Department of Manpower of Parepare City as the manager and implementer of training through UPTD BLK Kota Parepare. Data collection techniques used are Document study, observation, and interview. Data analysis techniques include: (a) Data processing, which consists of categorization and data reduction, (b) data presentation, (c) data interpretation, and (d) drawing conclusions/verifications. The results show that (1) The development of creative industries through entrepreneurship training includes: Information and Communication Technology, Garment Apparel, Beauty, Building, Electrical Engineering, Electronic Engineering, Refrigeration, Manufacturing Engineering, and Welding Technique; (2) The usefulness of the implementation of entrepreneurship training that can shorten the learning period, improve business performance, establish attitudes, help solve business operational problems, prepare entrepreneurs to acquire expertise in certain fields, and produce output that has the ability and knowledge that qualified (3) There are several factors that support and hinder the development of creative industries through entrepreneurship training in developing creative industries, both internal and external factors, and (4) development strategy based creative industry entrepreneurship in an effort to develop the local economy of recruitment and selection of trainees, selection of training instructors, the provision of facilities and infrastructure, curriculum development, and the provision of funds or training budgets.
Strategi Jigsaw Dalam Meningkatkan Minat Belajar Mahasiswa Pada Semester Ganjil Program Studi Manajemen STIE Kridatama Bandung tahun 2017-2018
Authors: Endah Fajariana Dewi
Published: November 2019

Environmental changed requires organizations to adapt. Organizations must integrated both internally and innovatively. The quality of education in educational institutions affects the quality of education nationally. Where the quality, determined by the students, lecturers, curriculum, learning strategies, media, infrastructure, time, availability of funds, community and socio-culture. Thus, every educational institution was no exception Institute of Economic Science Kridatama Bandung needed a new learning strategy. STIE Kridatama Bandung Campus Majority of student employees were required to receive higher education by companies and institutions where they work, then there must be problems as follows: a) Lazy learning, b) No concentration when lecturers explained, c) Passive students when lecturers explained, d) Own discussion with other friends, e) Gain low grades, therefore special handling needed to address such issues with innovative learning strategies such as jigsaw. The research method used was qualitative approach through observation on 84 students with the provision of UTS and UAS tests for their interest in learning. From the results of research implementation, the learning done by lecturers through jigsaw strategy, student activity showed there was improvement. Thus, the lecturer's learning process and learning strategy of one unity can not be separated. In conclusion, that lecturers and learning strategies were needed in supporting the learning process in universities to achieve quality education.