bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic predisposition to neural crest-derived tumors: revisiting the role of KIF1B
Authors: Cardot Bauters Catherine , Leteurtre Emmanuelle , Carnaille Bruno , Do Cao Christine , Espiard Stéphanie , Penven Malo , Destailleur Evelyne , Szuster Isabelle , Lovecchio Tonio , Leclerc Julie , Frénois Fredéric , Esquivel Emmanuel , Dahia Patricia L M , Ait-Yahya Emilie , Crépin Michel , Pigny Pascal
Published: October 2020

Objective

We previously described a family in which predisposition to pheochromocytoma (PCC) segregates with a germline heterozygous KIF1B nucleotide variant (c.4442G>A, p.Ser1481Asn) in three generations. During the clinical follow-up, one proband’s brother, negative for the KIF1B nucleotide variant, developed a bilateral PCC at 31 years. This prompted us to reconsider the genetic analysis.

Design and methods

Germline DNA was analyzed by next-generation sequencing (NGS) using a multi-gene panel plus MLPA or by whole exome sequencing (WES). Tumor-derived DNA was analyzed by SnapShot, Sanger sequencing or NGS to identify loss-of-heterozygosity (LOH) or additional somatic mutations.

Results

A germline heterozygous variant of unknown significance in MAX (c.145T>C, p.Ser49Pro) was identified in the proband’s brother. Loss of the wild-type MAX allele occurred in his PCCs thus demonstrating that this variant was responsible for the bilateral PCC in this patient. The proband and her affected grandfather also carried the MAX variant but no second hit could be found at the somatic level. No other pathogenic mutations were detected in 36 genes predisposing to familial PCC/PGL or familial cancers by WES of the proband germline. Germline variants detected in other genes, TFAP2E and TMEM214, may contribute to the multiple tumors of the proband.

Conclusion

In this family, the heritability of PCC is linked to the MAX germline variant and not to the KIF1B germline variant which, however, may have contributed to the occurrence of neuroblastoma (NB) in the proband.
Influência do acesso a saneamento básico na incidência e na mortalidade por COVID-19
Authors: Aquino Davi Santiago
Published: October 2020

A falta ou a escassez de saneamento básico pode causar consequências negativas à saúde de uma população. Esta pesquisa objetivou analisar a influência do acesso a abastecimento de água e a esgotamento sanitário na incidência e na mortalidade por COVID-19, pelo uso de regressão linear múltipla. Utilizaram-se dados de população urbana e total relativas aos estados brasileiros e foram testados 4 cenários para se avaliar a influência desses dados nas taxas de incidência e de mortalidade por COVID-19 acumuladas 90 dias após a confirmação do primeiro caso no Brasil. As equações obtidas para os cenários nos quais se testou a influência dos dados de saneamento na incidência foram estatisticamente significativas pelo teste F de Fisher a 5% de significância, tanto para população urbana quanto total, com valores negativos dos coeficientes de influência. Em contrapartida, a influência desses aspectos sanitários apresentou p-valor superior a 0,05 na taxa de mortalidade para as populações urbana e total e, portanto, não foi significativa. Os resultados indicam que o maior acesso a adequados serviços de saneamento básico está relacionado a menores taxas de incidência por COVID-19 no Brasil.
Palavras-chave: Abastecimento de água; coronavirus; correlação linear; esgotamento sanitário; SARS-CoV-2.
Comparison of Dehydrated Human Amnion-Chorion and Type 1 Bovine Collagen Membranes in Alveolar Ridge Preservation: A Clinical and Histological Study
Authors: Faraj Samer A. , Kutkut Ahmad , Taylor Robert C. , Villasante-Tezanos Alejandro , Huja Sarandeep S. , Dawson Dolphus R. , Almehmadi Nehal , Al-Sabbagh Mohanad
Published: October 2020

Alveolar ridge preservation maintains ridge dimensions and bone quality for implant placement. The aim of this randomized controlled clinical study is to compare the use of a human amnion-chorion membrane to a collagen membrane in an exposed-barrier ridge preservation technique. Furthermore, this study will determine if intentional membrane exposure compromises ridge dimensions and bone vitality. Forty-three patients requiring extraction and delayed implant placement were randomly assigned into either the experimental or control group. Twenty-one participants received human amnion-chorion membrane (test) during ridge preservation while 22 participants received the collagen membrane (control). In both groups, demineralized freeze-dried bone allografts were used to graft the socket and primary closure was not achieved. The patients underwent implant placement after an average healing period of 19.5 weeks, and 2.7 × 8-mm core bone specimens were obtained for histomorphometric analyses. The clinical ridge dimensions were measured after extraction and at the time of delayed implant placement. No significant difference was observed in the mean vital bone formation between the experimental (51.72 ± 8.46%) and control (49.96 ± 8.31%; P > .05) groups. The bone height and width did not differ, as determined by clinical measurements (P > .05). Using either a human amnion-chorion membrane or type 1 bovine collagen as the open barrier did not change healing, compromise ridge dimensions, or affect bone vitality between the 2 groups.
Functional Endoscopic Sinus Surgery for Paranasal Sinusitis Originating From a Peri-implantitis–Triggered Infection in the Augmented Maxilla: A Case Report
Authors: Park Won-Bae , Kim Young-Jin , Herr Yeek , Lim Hyun-Chang
Published: October 2020

The aim of this case report was to report the course of treatment for advanced paranasal sinus infection triggered by peri-implantitis, managed using functional endoscopic sinus surgery (FESS), with outcomes. A nonsmoking male patient received sinus augmentation with implant placement on his left posterior maxilla 15 years ago. Possibly due to noncompliance to maintenance, peri-implantitis developed and progressed into the augmented bone area in the maxilla. Eventually, maxillary sinusitis occurred concomitantly with a spread of the infection to the other paranasal sinuses. Implant removal and intraoral debridement of inflammatory tissue were performed, but there was no resolution. Subsequently, FESS was performed, with removal of nasal polyp and sequestrum. After FESS, the patient's sinusitis resolved. Histologically, the sequestrum was composed of bone substitute particles, necrotic bone, stromal fibrosis, and a very limited cellular component. Two implants were placed on the present site, and no adverse event occurred for up to 1 year after the insertion of the final prosthesis. Peri-implantitis in the posterior maxilla can trigger maxillary sinusitis with concomitant infection to the neighboring paranasal sinuses. FESS should be considered to treat this condition.
In Vitro Evaluation Of Naproxen Metabolite, O-Desmethylnaproxen On A Mouse Connective Tissue Fibroblast Cells
Authors: AKBAY Esin , ARACAGÖK Y. Doruk , GÖKER Ali Hakan , ONUR Mehmet Ali , CİHANGİR Nilüfer
Published: October 2020

The aim of this in vitro study was assessment of the cytotoxic level of 6-O-desmethylnaproxen. A mouse connective tissue fibroblast cell line, L929 was exposed to naproxen and 6-O-desmethylnaproxen in different concentrations for 24- and 48- hours. Cell viability was tested by MTT, while apoptosis was determined by AO/PI double staining method. The control group was free from any agent (DMEM only) and accepted as 100% cell viability. The IC50 results indicated that the inhibition of 50% cell viability was resulted by the highest concentration of 6-O-desmethylnaproxen (0.7 µg/mL) while none of naproxen concentration was caused 50% cell dead. Consequently, to avoid the unacceptable side effects of naproxen metabolites that evacuated by urine; further studies should be conducted to determine the accumulation of naproxen metabolites.
Do Russian Small Businesses Need a New Strategy?
Authors: Buchwald Evgeniy , Valentik Olga
Published: October 2020

The article aims to summarize some interim results of the implementation of the adopted in 2015 Strategy for the development of Russian small and medium-sized businesses until 2030, as well as to determine how this strategic planning document meets new conditions, which have appeared in the Russian economy, and in particular in the small and medium-sized business sector by 2020. The authors focus on both stronger and less successful provisions of the Strategy for the development of Russian SMEs, and also consider it necessary to determine how the Strategy mentioned above “fits” into the general outline of strategic planning documents, defined by the 172nd Federal Law on strategic planning. The article analyzes the difficulties, which currently accompany the implementation of the Strategy for the development of Russian SMEs and contains assumptions about the possibility of technical implementation of target indicators for the development of the SME sector in the Russian economy, fixed in the Strategy for the development of SMEs until 2030. The attention is drawn to the role of the national project “Small and medium-sized entrepreneurship and support for individual entrepreneurial initiative”, which can be considered as a reference point and action plan for the initial period of the implementation of the Strategy for SMEs development until 2030. The article focuses on the discussion of whether the Strategy for the development of SMEs until 2030 can be considered a real “working” document of public administration, or whether this vector of socio-economic policy of the state currently needs a new strategic concept, a new goal-setting methodology, a more detailed system of institutions and tools, and the disclosure of the spatial “cross-section” of public policy devoted to the SME sector, taking into account the strengthening of the role of regional and municipal management.
Crossbreed Cattle: Assessment and Challenges of Breeding in Selected Districts of Tigray and Afar Regional States, Ethiopia
Authors: Nagy Henrietta , Abdulkadr Ahmed , Neszmélyi György
Published: October 2020

The practice of animal husbandry has played an important role in enhancing sustainable development and improving food security of the community. However, the contribution of this sector towards the national as well as regional economy is very small. The focus of this research is to identify the main reasons why rural farmers do not own rear crossbreed cattle. The data obtained reveals that the majority of the rural communities dont have the right knowledge about the importance of crossbreed cattle in terms of their high yield. Some of the rural residents who are aware said they have limited financial access to afford crossbreed cattle. Besides, the respondents replied that the lack of appropriate feed and its high consumption is another reason, although the output gained from crossbreed cattle is quite high compared to the indigenous animals. Therefore, with the available livestock resource in Ethiopia it is recommended to increase the awareness of importance of crossbreed cattle, and government should also focus on creating favorable conditions to access to financial resources and feed for cattle. Solving the main bottlenecks will assure sustainable development and enable to meet the growing demand of the region. In addition to this, the income disparities between farmers and other self and government employed resident can be minimized.
Modelling of heat and mass transfer through wooden buildings
Authors: Méchi Rachid , Miszewska Emilia , Slimi Khalifa , Jankowski Robert
Published: October 2020

The aim of this review paper is to examine the most recent available studies dealing with theoretical, numerical and experimental aspects related to modelling of heat and mass transfer through wooden buildings. First, the main thermophysical, mechanical and hygrometric properties of wood are discussed. Then, the basic governing equations of heat and mass transfer phenomena are presented. A detailed description of the physical problem is also shown. After providing the main results from a comprehensive literature review, the authors propose future possibilities of scientific research studies for a better understanding of the complexity of thermomechanical and optimal designing aspects in wood-based construction.
Effect of aperture ratio on the cyclic shear behaviour of aggregate-geogrid interfaces
Authors: Wang J. , Liu F. Y. , Zheng Q. T. , Cai Y. Q. , Gou C. F.
Published: October 2020

In order to study the effect of aperture ratio (geogrid aperture size (AS)/average particle size (D50)) on the shear behaviour of aggregate–geogrid interfaces, a series of monotonic direct shear (MDS) tests, cyclic direct shear (CDS) tests and post-cyclic monotonic direct shear (PCDS) tests were carried out on two particle-shaped reinforced interfaces at five values of AS/D50. The cyclic shear behaviour of the two interfaces under three displacement amplitudes is discussed, and the interface shear characteristics before and after cyclic shear are analysed. The test results indicate that four possible cyclic shear behaviours can occur for two reinforced interfaces, including shear hardening (H), cyclic cumulative softening (SI), direct softening (SII) and wave softening (SIII). With increasing amplitude, the cyclic shear response of both interfaces changes from shear hardening to shear softening. The vertical displacements of both interfaces indicate an overall shear contraction trend in the CDS tests. The stiffness of two reinforced interfaces was significantly affected by the displacement amplitude and the ratio AS/D50. Compared with the maximum dilation of two reinforced interfaces in the MDS tests, the corresponding value has increased in the PCDS tests; the increase is more significant at rounded aggregate-geogrid interfaces.
Modelling of strength and energy absorption capacity of hybrid fibre-reinforced concrete
Authors: Chella Gifta Christopher , Gopal Ramesh
Published: October 2020

This study presents an estimate of various strength and toughness properties of steel–polyester hybrid fibre-reinforced concrete obtained using artificial neural network techniques. Input parameters used in the development of single and hybrid fibre-reinforced concrete composites in the experimental programme were given as input variables in artificial neural network models. The constituents of concrete, such as cement, fly ash, silica fume, sand, coarse aggregate, water, chemical admixture, steel fibre, polyester fibre and its combinations, were used as input parameters in artificial neural network modelling. Two artificial neural network models were proposed, trained, tested and validated to predict the compressive strength, split tensile strength, flexural strength, impact resistance and energy absorption capacity of single and hybrid fibre-reinforced concrete composites. The performances of these two artificial neural network models were compared based on probabilistic analysis. Regression plots made between experimental output and predicted output values yielded good correlation. From the regression plots, it is understood that this neural network is an effective tool in predicting the strength or toughness of the steel–polyester hybrid fibre-reinforced composites. By adopting these neural network techniques, expensive laboratory arrangements, costs of testing, and waits for curing time could be saved.
Making future floating cities sustainable: a way forward
Authors: Umar Tariq
Published: October 2020

It is expected that by 2030, 5 billion of the earth's population will live in cities. This growth in urbanisation results in significant challenges pertaining to environmental and social sustainability. Most of the cities are located near coastal areas and thus under the threat of sea rise. This paper explores sustainable floating cities with the key sustainable factors as an alternative to meet the requirement of future urbanisation. The purpose of this paper was to find the key sustainability factors and then explore the solutions to achieve them in the sustainable floating cities. A mixed research strategy using qualitative and quantitative approaches was adopted to achieve the aims of this research. The key sustainability factors were derived from the existing literature using a systematic review approach and then ranked using a questionnaire administrated among selected respondents. The top-ranked factors that include energy, water, food, waste, mobility and habitat regeneration were considered and were further explored using a systematic review method. The review suggests that there are different arrangements and techniques available to meet the requirement of future sustainable floating cities. The discussion reveals that the concept of floating cities is at its initial stage and has the potential for multidisciplinary research.
Yoğun Bakım Ünitesinde Hasta Örneklerinden İzole Edilen Kandida Türlerinin ve Kandidemi Risk Faktörlerinin Değerlendirilmesi
Authors: KERGET Ferhan , KERGET Buğra , KARAŞAHİN Ömer , ÇELİK Neslihan , İBA YILMAZ Sibel
Published: October 2020

Amaç: Kandida kan dolaşım
enfeksiyonları ciddi, hayatı tehdit edici hastalıklardır. Böyle bir hastalığın
epidemiyolojisini ve risk faktörlerini anlamak hastalığa daha erken tanı
konulmasını ve erken, etkin tedavi planlanmasına yardımcı olacaktır.

Gereç ve Yöntem: Çalışmamızda
hastanemiz üçüncü basamak yoğun bakım ünitesinde takip edilen erişkin
hastalarda çeşitli örneklerden üreyen kandida türlerini ve kandidemi risk
faktörlerini belirlemeyi amaçladık. Yoğun bakım ünitemizde bir yıl boyunca
takip edilen erişkin hastaların verileri retrospektif olarak incelendi.

Bulgular: Toplam 72 hastanın çeşitli
örneklerinde kandida üremesi oldu. Hastaların 30’unda kan kültüründe, 58’inde
idrar kültüründe, 5’inde yara kültüründe, 32’sinde trakeal aspirat kültüründe
kandida üremesi oldu. Kan kültür üremelerinde kandida tipleri; Candida
parapsilosis (%43,3), Candida albicans (%40), Candida glabrata (%10), Candida
tropicalis (%3,4), Candida cruise (%3,3) olarak tespit edildi. Santral venöz
katater bulunması, total paranteral nutrisyon verilmesi ve cerrahi operasyon
geçirilmesi kandidemi için önemli bir risk faktörü olarak gözlendi (p:0,019,
p:0,001, p:0,001). Kandidemi gelişen hastaların kandidemi tespit edildiği
sırada ve diğer hastalardan mevcut üremeleri esnasında alınan laboratuvar
parametrelerinin karşılaştırılmasında sodyum, magnezyum, CRP, lökosit,
prokalsitonin düzeylerinde kandidemi gelişen hastalarda daha yüksek olmak üzere
istatistiksel olarak anlamlı fark gözlenmişken (p:0,001,0,027,0,001,0,034,0,001),
albümin düzeyi kandidemi gelişmeyen hastalarda istatistiksel olarak anlamlı
düzeyde yüksek idi (0,04). Non-C.albicans üremesi olan hastaların yoğun bakım
yatış süreleri C.albicans üreyen hastalara nazaran daha yüksek olarak gözlendi
(p:0,032). Tüm nedenlere bağlı kandidemi sonrası 30 günlük mortalite oranı
%57,1 olarak tespit edildi.

Sonuç: Çalışmamız verileri
doğrultusunda santral venöz katater kullanımı, total parenteral nutrisyon
verilmesi ve geçirilmiş cerrahi operasyon kandidemi için risk faktörlerinin başında
gelmekteydi. Ayrıca non-C.albicans üremesi olan hastalarda yoğun bakım yatış
süresi C.albicans üremesi olanlara nazaran daha uzun olarak gözlendi.
Fire-Sale Vulnerabilities of Banks: Bank-Specific Risks under Stress and Credit Drawdowns
Authors: Shin Chaehee , White Maddie
Published: October 2020

One channel of shock propagation in the financial system is fire-sale-driven spillover that can take place through asset fire sales and the resulting effect of depressed asset prices on the value of firms' assets. Heightened leverage then induces firms to de-lever, triggering another round of asset fire sales.
Estimates of r* Consistent with a Supply-Side Structure and a Monetary Policy Rule for the U.S. Economy
Authors: Gonzalez-Astudillo Manuel , Laforte Jean-Philippe
Published: October 2020

We estimate the natural rate of interest (r*) using a semi-structural model of the U.S. economy that jointly characterizes the trend and cyclical factors of key macroeconomic variables such as output, the unemployment rate, inflation, and short- and long-term interest rates. We specify a monetary policy rule and an equation that characterizes the 10-year Treasury yield to exploit the information provided by both interest rates to infer r*. However, the use of a monetary policy rule with a sample that spans the Great Recession and its aftermath poses a challenge because of the effective lower bound. We devise a Bayesian estimation technique that incorporates a Tobit-like specification to deal with the censoring problem. We compare and validate our model specifications using pseudo out-of-sample forecasting exercises and Bayes factors. Our results show that the smoothed value of r* declined sharply around the Great Recession, eventually falling below zero, and has remained negative since then. Our results also indicate that obviating the censoring would imply higher estimates of r* than otherwise.
Presencia y tratamiento de la cultura
Authors: Manadé Rodríguez Carlos , Rodríguez Álvarez Alicia
Published: October 2020

El trabajo propuesto analiza cinco manuales de ele empleados en Japón con el fin de valorar (a) la forma de integrar los contenidos culturales en estos volúmenes, (b) el tipo de contenidos culturales que reciben más atención (siguiendo la clasificación de Miquel y Sans, 1992), (c) el desarrollo de la competencia intercultural y, finalmente, (d) la presencia de un elemento sociocultural que se manifiesta de muy distintas formas en las culturas observadas: el humor. Los resultados revelarán, por un lado, algunos patrones comunes en cuanto al modo de integrar estos contenidos en los manuales, y, por otro, diferencias en la tipología de los contenidos tratados y la promoción del espíritu crítico asociado a la competencia intercultural. Por último, resulta muy llamativo el nulo interés que se presta a las manifestaciones verbales del humor, un elemento muy presente en el español coloquial y causante de muchos malentendidos en las interacciones sociales.
https://doi.org/10.17398/2660-7301.41.115
Los falsos retratos del “teatro selecto”: la canonización visual de dramaturgos barrocos por la recepción nacionalista decimonónica
Authors: Bermejo Gregorio Jordi
Published: October 2020

En el segundo y tercer tomo de la colección Teatro selecto, antiguo y moderno, nacional y extranjero (1867, y editada por Francisco de Orellana) aparecieron siete ilustraciones de dramaturgos áureos, obras de Tomás Padró. Mientras que los rasgos de Solís y de Moreto aparecían fieles a los retratos contemporáneos de los autores, los de Ruiz de Alarcón, Rojas Zorrilla, Pérez de Montalbán, Zamora y Cañizares estaban trazados por un mismo y sospechoso patrón. Este trabajo pretende estudiar la canonización e idea¬lización visual del escritor áureo en el siglo XIX, producto de la ideología nacionalista conservadora del periodo y reflejo de la recepción decimonónica de la literatura áurea.
https://doi.org/10.17398/2660-7301.41.27
Digital Public Sphere and Geography: The Influence of Physical Location on Twitter’s Political Conversation
Authors: Casero-Ripollés Andreu , Micó-Sanz Josep-Lluís , Díez-Bosch Míriam
Published: October 2020

Social media has instituted new parameters for the political conversation in the digital public sphere. Previous research had identified several of these new phenomena: political polarisation, hate speech discourses, and fake news, among others. However, little attention has been paid to the users’ geographical location, specifically to the role location plays in political discussion on social media, and to its further implications in the digital public sphere. A priori, we might think that on the digital landscape geographical restrictions no longer condition political debate, allowing increasingly diverse users to participate in, and influence, the discussion. To analyse this, machine learning techniques were used to study Twitter’s political conversation about the negotiation process for the formation of the government in Spain that took place between 2015 and 2016. A big data sample of 127,3 million tweets associated with three Spanish cities (Madrid, Barcelona, and Valencia) was used. The results show that the geographical location of the users directly affects the political conversation on Twitter, despite the dissolution of the physical restrictions that the online environment favours. Demographics, cultural factors, and proximity to the centres of political power are factors conditioning the structure of digital political debate. These findings are a novel contribution to the design of more effective political campaigns and strategies, and provide a better understanding of the dynamics of the digital public sphere provided by Twitter.
Political Opinion Formation as Epistemic Practice: The Hashtag Assemblage of #metwo
Authors: Berg Sebastian , König Tim , Koster Ann-Kathrin
Published: October 2020

The article contributes to the literature on the political use of hashtags. We argue that hashtag assemblages could be understood in the tradition of representing public opinion through datafication in the context of democratic politics. While traditional data-based epistemic practices like polls lead to the ‘passivation’ of citizens, in the digital constellation this tendency is currently challenged. In media like Twitter, hashtags serve as a technical operator to order the discursive fabrication of diverse publicly articulated opinions that manifest in the assemblage of tweets, algorithms and criticisms. We conceptualize such a critical public as an epistemic sensorium for dislocations based on the expression of experienced social imbalances and its political amplification. On the level of opinion formation, this constitutes a process of democratization, allowing for the expression of diverse opinions and issues even under singular hashtags. Despite this diversity, we see a strong tendency of publicly relevant actors such as news outlets to represent digital forms of opinion expression as unified movements. We argue that this tendency can partly be explained by the affordances of networked media, relating the process of objectification to the network position of the observer. We make this argument empirically plausible by applying methods of network analysis and topic modelling to a dataset of 196,987 tweets sampled via the hashtag #metwo that emerged in the German Twittersphere in the summer of 2018 and united a discourse concerned with racism and identity. In light of this data, we not only demonstrate the hashtag assemblage’s heterogeneity and potential for subaltern agency; we also make visible how hashtag assemblages as epistemic practices are inherently dynamic, distinguishing it from opinion polling through the limited observational capacities and active participation of the actors representing its claims within the hybrid media system.
Ambivalent Prospection: Covid-Related Attitudes in Patients with Substance Dependence
Authors: Tuchina O.D. , Agibalova T.V. , Panov A.S. , Shustov D.I. , Bryun E.A. , Buzik O.Z.
Published: October 2020

The study explored associations between individual characteristics that are considered markers of suicidal and non-suicidal self-destruction (substance dependence; hopelessness, and impulsiveness), prospection (or future thinking), and attitudes to a novel coronavirus infection (COVID-19). After all inclusion/exclusion criteria were met, the sample (N=102) included two comparison groups: Group 1 comprised male in-patients diagnosed with substance dependence (N=62), and Group 2 consisted of males without this diagnosis (N=40). Methods: Beck’s Hopelessness Scale; Barratt’s Impulsiveness Scale (BIS-11); self-defining future projections (SDFP) generation task; COVID-19 self-report measure. Results: Groups had almost similar levels of declared COVID-related attitudes, but differed significantly in impulsiveness and hopelessness. SDFPs in Group 1 differed from those in Group 2 as to their phenomenological (shorter time perspective; more negative; less frequently simulated), content (higher frequency of Relationship and lower frequency of Achievement events), and psychological characteristics (lower Competence and Autonomy). Groups had different patterns of correlations between COVID-related and psychological parameters associated with self-destruction, as well as between all these parameters and SDFP characteristics. We also found evidence in favor of the hypothesis regarding protective function of prospection. Conclusions: We were able to confirm the association between dysfunctional COVID-related attitudes and individual characteristics that are frequently considered to be markers of non-suicidal self-destruction only partially. Nonetheless, the identified dissociation between declared COVID recognition and willingness to observe epidemiological precautions and actual neglect of those may require future study.
Efficacy of Myrmecodia Platytyrae (MyP) Water Extract in Reducing Cholesterol Level in Hypercholesterolemia Induced Sprague Dawley Rat
Authors: Hasan M. K. Nik , Wahab I. Abdul , Mizaton H. H. , Rasadah M. A.
Published: October 2020

Myrmecodia plant or ant-nest plant is from Rubiaceae family. Rubiaceae are mainly tropical woody plants, consist mostly of trees and shrubs and can be found in temperate regions. Myrmecodia platytyrea (MyP) are believed to have medicinal value.  This study was designed in order to investigate the effect of MyP extract as anti hypercholesterolemic agent. The results showed that treatment of MyP can significantly reduce (p<0.05) low density lipoprotein (LDL) compared to negative control group. The extract was significantly increase (p<0.05) high density lipoprotein (HDL) concentration compared to negative control group. Besides that, MyP increased fecal cholesterol and fecal bile compared to normal control group. It was also found that lipid profile was significantly decreased (p<0.05) in MyP treatment group. All biochemistry data showed that MyP water extract was not toxic at all.
Homeopathic Approach to COVID-19: A Review
Authors: Hasan Nazmul , Nayem Mesbah Uddin Md. Rezwanun , Mohshinuzzaman Mohammad , Biswas Anwar H , Kayes Md. Emrul , Hakim Md. Abdul , Uddin Nizam , Alom Md. Jahangir
Published: October 2020

Novel coronavirus 2019-nCoV-2 infection, also known as COVID-19, has a pandemic outbreak, and recent studies show various limitations, including treatment. This virus is chiefly infecting the respiratory tract (RTI) and resulting in Severe Acute Respiratory Syndrome. Many developed countries, including Italy, England, and the United States of America (USA), are facing many casualties. Unlikely, no specific treatment protocol is available till today. Homeopathic medicine is a branch of alternative medicine, practiced on individualized symptoms similarity. However, historically it has potential in treating epidemic infections like scarlet fever, typhoid, and cholera. In the treatment of RTI and pneumonia, several homeopathic medicines have proven efficacy. This review on the utility of homeopathic medicine might guide the physician to prevent COVID-19 contagion. Homeopathic medicines can help humanity with conventional medical methods to prevent this global catastrophe.
Assessment of Eucalyptus Globulus Coppice Yield in the Highland Areas of North Shewa, Ethiopia
Authors: Woldeamanual Lemma Habteyohannes , Reta Getabalew Teshome , Nigussie Melese Bekele , Tsedeke Reta Eshetu , Zenebe Hailemariam Fiseha , Wudineh Damtew Ababu
Published: October 2020

One of the old traditional methods of silvicultural management is coppicing. Many woody species produce new shoots successfully after coppicing. Regeneration of forest through coppice can be used for short rotation of tree to produce wood biomass for construction and fuel purposes. There are different levels of coppice practiced in Eucalyptus globulus plantation in the highland areas of North Shewa. However, there was no evidence or study which coppice levels can give high yield. Therefore, the objective of this study was to compare yield of E. globulus at different coppice level in the highland areas of North Shewa, Ethiopia. Fifty sampled plots were purposively selected for this study. Volume, mean annual increment, stump height and diameter, stem number and harvesting age were determined from sampled plots. The results revealed that there was no yield difference (p> 0.05) between zero, first, second and third coppice levels. However, stump diameter and number of shoots per stump, stump height were significantly different among 1, 2, 3 coppice levels (p<0.05). Number of shoots were positively correlated with stump diameter and height (r = 0.77, r = 0.72) respectively. Farmers mostly coppice E.globulus from November to December and from April to June. Although statistically there was no yield difference between coppice levels, as farmers described the first coppice has higher yield than other coppice levels. The numbers of shoots per stump were higher in the second and third coppice and this could affect stem quality especially at early stage. Altogether the mean number of stems per hectare was 10812 which is higher than previous studies. Therefore, early silvicultural activities like thinning, early coppice management and pruning has to be done to increase wood stem quality and to promote growth as well.
Provenance of the Ciénaga de Oro Formation: unveiling the tectonic evolution of the Colombian Caribbean margin during the Oligocene - Early Miocene
Authors: Manco-Garcés Alejandra , Marín-Cerón Maria Isabel , Sánchez-Plazas Carlos Javier , Escobar-Arenas Luis Carlos , Beltrán-Triviño Alejandro , von-Quadt Albrecht
Published: October 2020

A stratigraphic section in the San Jacinto fold and thrust belt located at northwestern Colombia was studied. This section displays part of the Oligocene-Early MioceneCiénagade Oro Formation(COF).This work analyses thesedimentsprovenance usinga multi-tool approach which include: (I)conglomerate and sandstonecounting clastwith mesh,(II)heavy mineralsassemblages, (III)paleocurrents and (IV) U/Pb detrital zircon ages.The sedimentary sequence was deposited in deltaic to transitional environment deposition, with reduction in the waves and tidal effect, and increase in the dominance of transitional river processes upward the section. Two main source areas have been identified from a dissected arc province: a main granitic to pegmatitic and a secondary basic igneous source rocks, located to the east and southwest of the current position. Detrital zircon U-Pb geochronology analysis display four age populations: (I) Devonian-Permian, (II) Permian-Triassic, (III) Jurassic and (IV) Cretaceous, with maximum deposition ages of 75.2±0.9 Ma in the lower part of the section, 68.9±0.6 Ma in the middle and 74.5±0.7 Ma for the upper part. It is proposed that COF was sediment-supplied by a south-to-north fluvial system, which drained exposed basement blocks and their late Cretaceous to Paleogene sedimentary cover during the Oligocene. This fluvial system carried sediments from late Cretaceous plutonslike the AntioqueñoBatholith and mafic/ultramafic rocks, which make up the basement of the Western and Central Cordilleras
Consideraciones generales para la elaboración de un atlas de almacenamiento geológico de CO2 del Perú
Authors: Paredes-Ángeles Jorge Humberto
Published: October 2020

La captura y el secuestro o almacenamiento geológico de CO2 es la mejor alternativa para reducir el exceso de emisiones de CO2 antropogénico al medio ambiente, tanto por consideraciones técnicas como económicas. Los volúmenes de almacenamiento de CO2 y los tiempos de residencia prolongados en los depósitos geológicos lo hacen particularmente interesante. Aunque no se ha probado a gran escala, los diferentes proyectos piloto realizados y los que están en ejecución en varias partes de Europa y Norteamérica muestran resultados muy alentadores.En este trabajo se desarrollan los principios más importantes que hay que tomar en cuenta al elaborar un atlas de almacenamiento geológico de CO2. Se hace una revisión de los fundamentos teórico-prácticos para el secuestro geológico de CO2, también se desarrollan los tipos y mecanismos de retención del dióxido de carbono en las diferentes formaciones geológicas, luego se revisan los principales criterios de selección de los emplazamientos y los indicadores de idoneidad de los sitios para el secuestro de dióxido de carbono. Se presenta un sistema de clasificación de los sitios en función del conocimiento geológico de la formación seleccionada que es una adaptación de la experiencia geológica en la exploración de petróleo y gas. Se proponen tentativamente las áreas geográficas a investigar e información geológica a recabar y procesar en función a los potenciales almacenes existentes y también se expone la metodología para la estimación de los recursos de almacenamiento o secuestro geológico de dióxido de carbono en función de las formaciones que podrían ser encontradas
Суфизм как гностическое учение в исламе
Authors: Королёв Юрий Алексеевич
Published: October 2020

Являясь мистическим течением в рамках исламского креационизма и внешне признавая его доктрины, суфизм представляет по сути дела иную, противоположную исламу, манифестационисткую мировоззренческую традицию. Интерпретируя священные тексты и догматы мусульман с позиции эманационизма, суфизм во многом выходит за пределы ислама, утверждая нетрадиционный для ислама путь познания Бога. Этот путь представляет собой своеобразное восхождение по ступеням духовного совершенства и обретение высшего знания – гносиса. Восприятие суфиями гносиса в качестве высшего этапа богопознания дает основание для проведения сравнительного анализа между главными положениями суфийской доктрины и представлениями гностиков о мире, человеке, Боге и путях Его постижения. В результате этого анализа обнаруживается почти полная тождественность этих двух доктрин (суфизма игностицизма), что позволяет сделать вывод о гностическом характере суфизма.
Seguridad de la histerectomía total por laparoscopia entre el 2007 y 2017 en un hospital de alta complejidad, Pereira, Colombia. estudio de cohorte
Authors: Bastidas-Guarín Claudia , Zambrano-Moncayo Claudia Patricia , López-Isanoa Jorge Darío , López-Jaramillo José Duván , Herrera-Betancourt Ana Lucía , Cuello-Salcedo Angélica , Gutiérrez-Calderón Eliana , Piedrahíta-Gutiérrez Danny Leandro , Villegas-Echeverri Juan Diego
Published: October 2020

Objetivo: objetivo describir las complicaciones intra y posoperatorias de la histerectomía total por laparoscopia (HTL) para patología benigna del útero y hacer una comparación con otros hospitales que tienen altos volúmenes de HTL. Materiales y métodos: estudio de cohorte retrospectivo en mujeres que se sometieron a HTL por patología ginecológica benigna entre 2007 y 2017 en una institución privada de mediana complejidad, que atiende población perteneciente al régimen contributivo y subsidiado por el Estado en el Sistema General de Seguridad Social, en Pereira, Colombia, por el grupo de cirujanos del centro de entrenamiento ALGIA. Muestreo consecutivo. Se describen la características sociodemográficas y clínicas basales, los hallazgos intraoperatorios y las complicaciones intra y posoperatorias. Se usó estadística descriptiva. Resultados: en el periodo de estudio se incluyeron 1.350 pacientes. El tiempo quirúrgico fue de 95 min (DE ± 31), el sangrado quirúrgico 88 cc (DE ± 66), el peso promedio del útero fue de 236 g (DE ± 133). El 96,5% de las pacientes fueron evaluadas entre los 30 y 45 días. El 3,48% de las pacientes tuvieron complicaciones menores y el 2,5% complicaciones mayores. Tres pacientes requirieron conversión a laparotomía (0,23%). No hubo mortalidad en la muestra estudiada. Conclusión: la HTL es un procedimiento seguro y la tasa de complicaciones es similar a la de los mejores estándares internacionales. Es importante que se sigan haciendo estudios prospectivos con criterios objetivos de evaluación para comparar el desempeño de los diferentes grupos e instituciones que ofrecen procedimientos quirúrgicos y entrenamiento.
El papel del Estado, la Sociedad Civil y la escuela en las memorias de violencia
Authors: Ciro Solórzano Luisa Fernanda , Miguel Ángel Miguel Ángel
Published: October 2020

El presente artículo tiene como objetivo reflexionar sobre el papel del Estado, la Sociedad Civil y la Escuela en las dinámicas de memoria de los períodos de violencia posteriores a las dictaduras del Cono Sur y durante el conflicto colombiano. Para ello se apoya en los postulados de Traverso (2007), Halbawchs (2011) y en las narrativas de los informes especialiazados Nunca más (Argentina), Rettig y Valech (Chile) y ¡Basta ya! (Colombia). Se enmarca en una metodología de corte histórico-hermenéutico con un diseño de investigación documental. Después de describir las experiencias desiguales de cada país en cuanto a las tres categorías de análisis, el artículo concluye que Estado, Sociedad Civil y Escuela son responsables de reparar el tejido social afectado por la violación a los derechos humanos. En el caso del Estado, desde la validación en los procesos de reparación y justicia; en el de la Sociedad Civil, desde la lucha por la identidad y el reconocimiento; y en el de la Escuela, desde su condición como punto de encuentro para la discusión crítica de la polifonía de las memorias.
From Intuitionism to Brouwer's Modal Logic
Authors: Kostrzycka Zofia
Published: October 2020

We try to translate the intuitionistic propositional logic INT into Brouwer's modal logic KTB. Our translation is motivated by intuitions behind Brouwer's axiom p →☐◊p The main idea is to interpret intuitionistic implication as modal strict implication, whereas variables and other positive sentences remain as they are. The proposed translation preserves fragments of the Rieger-Nishimura lattice which is the Lindenbaum algebra of monadic formulas in INT. Unfortunately, INT is not embedded by this mapping into KTB.
A PORTRAIT OF SHARIA BUSINESS SYMBOLIZATION AND ITS SOLUTIONS
Authors: Jumaiyah Jumaiyah , Wahidullah Wahidullah
Published: October 2020

Abstract

The purpose of this study is to determine whether the knockout arisan money system is in accordance with sharia principles or not. The research method used is a qualitative descriptive method by observing, interviewing, and collecting documents as supporting data of KSPPS BMT Lumbung Artho Jepara Central Java Indonesia that implements the Yad Dhamanah Wadi'ah contract with the explanation that the stored assets or items can be used by aid providers and can also distribute to its members. However, the agreement is not in accordance with the fatwa of the National Sharia Council of Indonesian Majlis Ulama about the nature of Wadi'ah saving that deposits can be withdrawn according to the wishes of the depositors and not waiting for lottery numbers to take their deposits. Furthermore, the application of the bonus giving also deviates from the voluntary Wadi'ah contract and the bonus agreement at the beginning of the contract. However, because the practice of knockout arisan money system has already existed in the community, therefore the solution for its implementation is by using the agreement of the al-qardh (debt-receivable) and Mudharabah (profit-sharing) contracts that are closer to Islamic principles.

Keywords: Money Arisan, Falling Systems, Islamic Principles, Culture
Infracción de un derecho de marca en plataformas de ecommerce: la actuación de la plataforma y el impacto en su responsabilidad
Authors: Antón Juárez Isabel
Published: October 2020

Las plataformas de comercio electrónico se han convertido en verdaderos protagonistas en el intercambio de bienes y servicios. Muchas de estas plataformas son meros intermediarios y sólo alojan información (servicios de hosting). El papel que realizan otras, especialmente en los últimos años debido a cómo han cambiado los servicios digitales, ha dado lugar a que no sea tan fácil calificar su ac­tividad y mucho menos de englobarla dentro de la consideración de “meros intermediarios” que alojan datos. Sin embargo, determinar el rol, el tipo de actuación de este tipo de prestadores de servicios es un aspecto clave cuando se infringen derechos de propiedad industrial o intelectual en una plataforma de ecommerce. En el presente trabajo vamos a abordar dos análisis. Por un lado, se va a estudiar cuándo una plataforma usa una marca en el sentido del Reglmanto UE 2017/1001, sobre la marca de la Unión Europea. Por el otro, se analizará cuándo una plataforma aunque no use la marca se le puede considerar responsable por las infracciones que sobre la misma se están cometiendo en su plataforma.
Big data: gestión de recursos humanos y el derecho de información de los representantes de los trabajadores
Authors: Bernal Santamaría Francisca
Published: October 2020

Se expone los retos que plantea la Era Digital, y de forma concreta, la “Era de los Da­tos” junto a la afectación a derechos fundamentales, como es el de derecho a la protección de datos de candidatos y de trabajadores. En este reto se analiza el Reglamento 2016/679 relativo a la protección de las personas físicas en lo que respecta al tratamiento de datos personales y a la libre circulación de estos datos y su proyección en las relaciones laborales. A su vez, se plantea la necesidad de que el algoritmo que genera el volumen de datos a disposición de las empresas sea conocido por los representantes de los trabajadores como parte integrante de sus derechos de información.
Los artículos 9.2 y 9.3 del Código Civil y el régimen económico matrimonial en Derecho internacional privado español. Valores, métodos y técnicas
Authors: Calvo Caravaca Alfonso-Luis , Carrascosa González Javier
Published: October 2020

El presente estudio lleva a cabo un análisis de los arts. 9.2 y 9.2 del Código civil y de la relación entre ambos preceptos. Se pone de relieve que el art. 9.2 CC es la norma central del sistema, una norma que se ha quedado anticuada al otorgar demasiado espacio a la Ley personal y no admitir una elección clara y simple de la Ley aplicable a los efectos del matrimonio y de la ley aplicable a los contratos matrimoniales. Ambos preceptos están en pleno vigor y se aplican a los matrimonios celebrados antes del 29 de enero de 2019. Este trabajo sostiene que el art. 9.3 CC debe ser entendido como una norma que aumenta las posibilidades de validez de las capitulaciones matrimoniales en casos internacionales.
Cohesión territorial y transporte aéreo en España
Authors: Martín Osante José Manuel
Published: October 2020

El presente trabajo tiene por objeto el estudio del régimen jurídico de las denominadas obligaciones de servicio público previstas en el Reglamento (CE) n. 1008/2008 y su aplicación en las rutas aéreas españolas. Estas obligaciones constituyen medidas que limitan o excluyen el libre acceso de las compañías aéreas al mercado de la Unión Europea (UE), con la finalidad de evitar que determinadas rutas queden desatendidas por falta de rentabilidad económica, y para garantizar la cohesión territorial y la movilidad. En concreto, en este artículo se examina el alcance de las previsiones legales españolas y europeas sobre protección de la cohesión territorial, se incide en el régimen jurídico de la UE de las obligaciones de servicio público y se expone la aplicación en España de estas obligaciones.
La remisión y la transferencia de competencia en materia de responsabilidad parental en el Reglamento (UE) 2019/1111
Authors: Rodríguez Vázquez Mª Ángeles
Published: October 2020

Los arts. 12 y 13 del Reglamento (UE) 2019/1111 regulan de forma más detallada la remisión y la transferencia de competencia entre órganos jurisdiccionales de Estados miembros, reco­giendo en muchas de las nuevas reglas las soluciones ya avanzadas por el TJUE. No obstante, la falta de respuesta expresa a algunas cuestiones seguirá ocasionando problemas en su aplicación. Además en el art. 97.2.b) del Reglamento se aclara que con respecto a la transferencia de competencia entre un órgano jurisdiccional de un Estado miembro y un órgano jurisdiccional de un Estado parte del Convenio de La Haya de 1996 en el que no se aplique el Reglamento, se aplicarán los artículos 8 y 9 de dicho Convenio.