bluuebunny/crossref_metadata_2025 huggingface dataset:
‘Fate Leads the Willing, and Drags the Unwilling’
Authors: Cohen Judah M.
Published: February 2021

In this article, I explore the role that Austrian-born musicologist/composer Eric Werner (1901–1988) cultivated as a representative of musical Wissenschaft des Judenthums in postwar America. I focus here on the diary that Werner kept between 1955 and 1957 – a heretofore untapped resource – which chronicles his efforts to build intellectual refugee networks while simultaneously helping to restart an international network of Jewish music discourse spanning America, Europe and Israel. Music, in Werner’s view, required a scientific basis for study from which authentic practices could be rebuilt. Thus, while Werner relied on revitalising cantors as vessels of Jewish music, he viewed musicology as the core discipline from which Jewish music ‘tradition’ could arise.
Jesus Ben Sira 24
Authors: Bachmann Veronika
Published: February 2021

This article examines the theopoetic (re-)imagination of Wisdom at the centre of the Book of Jesus Ben Sira (chapter 24) and brings it into a dialogue with the prologue of the Gospel of John, where not Torah, but Jesus of Nazareth as logos is related to traditional concepts of Wisdom.
Aeromobilities of Student Newcomers in Francophone African Fiction
Authors: Toivanen Anna-Leena
Published: February 2021

In the field of postcolonial literary studies, representations of concrete forms of mobility have not received the critical attention they deserve. This is partly due to the field's reductive understanding of “mobility” as a synonym for migration. In order to enhance dialogue between postcolonial literary studies and mobilities research, this article focuses on representations of aeromobility in the context of Afroeuropean student mobilities in a set of Francophone African novels from the 1980s to the 2010s. My reading of scenes of aeromobility in the text corpus draws attention to the anxious aspects of the air travel of unaccustomed travelers and African newcomers traveling to the former colonial center, and explores the formal functions of representations of aeromobility in terms of narrative structures and tropes.
Análisis del sector productor y exportador de mango ecuatoriano bajo el enfoque de sostenibilidad, periodo 2014-2018
Authors: Trávez Changoluisa Bryan Paul , Pillajo Tipantuña Leslie Maricela , Viteri Moya Digna Marcela
Published: February 2021

El objetivo del presente estudio fue analizar el sector productor y exportador de mango, considerando las dimensiones económica, social y ambiental; la investigación es de tipo exploratorio debido a que se examinó un problema poco estudiado. Se utilizaron técnicas documentales y de campo, como entrevistas a los representantes de las empresas exportadoras de mango, con el objetivo de recopilar información primaria para determinar las condiciones actuales de la industria. Los resultados revelaron que, en cuanto a la dimensión económica, los ingresos por exportaciones de las empresas estudiadas se incrementaron. Sin embargo, existen irregularidades en las utilidades declaradas. Con respecto a la dimensión social se presentan dificultades con respecto a la generación de empleos permanentes y equidad social. Finalmente, en la dimensión ambiental se pudo concluir que, pese a que las empresas han implementado actividades orientadas a preservar el medio ambiente, aún existen problemas con respecto a la gestión adecuada de residuos.
Methods for extraction of mercury compounds from coal in Ukraine
Authors: Boruk S. D. , Kushnіr A. I. , Boruk O. S.
Published: February 2021

The ways of prevention of environmental pollution by coal-containing mercury compounds are investigated in the paper. Coal mercury compounds are harmful and toxic impurities. In coal, the mercury is in the form of sulfides and mercury-containing organic compounds. Considerable amounts of native mercury and cinnabar are also recorded. The content of the mercury in terms of metal in the Donbass coal ranges from 0.01 to 1000 g / t. The highest concentrations of mercury compounds are due to hydrothermal and volcanic processes. In Donbass coal, the content of mercury compounds is on average 5 to 10 times greater than the background compared to other coal basins. The most common form of mercury compounds in coal are impurities in sulfide minerals. The content of mercury compounds in pyrite is two orders of magnitude higher than in the organic coal component.

It is established that the bulk of the mercury compounds are contained in fine particles. The maximum content is fixed in a fraction of 0.1 - 15 microns. Thus, it can be assumed that the mercury compounds are predominantly contained in the mineral component of coal, which is more intensively ground. It is shown that washing with hot water and the complexing agent solution results in a decrease in the content of mercury compounds in the coal feedstock. The washing solutions become turbid, and this suggests that the mercury compounds are flushed out with fine particles. The increase in the degree of extraction of compounds of the mercury when applying the complexing solution is due to the ability of aurintricarboxylic acid to form complex compounds with the mercury ions. It can be assumed that in this case chemisorption occurs with the formation of complex compounds of the chelate structure on the surface of the particles, followed by dispersion of the particles of the dispersed phase. It was found that washing of the dispersed coal raw material is accompanied by weight loss. This indicates that the mercury compounds are leached from the coal in the form of dispersed particles. Waste sludge is to be disposed of with further disposal.
Optical properties of aqueous solutions of manganese (II) complexes with l-cysteine, thioglycolic acid and citrate - ion
Authors: Pylypko V. G. , Krupko O. V. , Shcherbak L. P.
Published: February 2021

Complexes of manganese (II)-ions with two thiols (amino acid L-cysteine and thioglycolic acid TGA) as well as with citrate ions are of a grate interest due to their important role in biosystems. Besides, they take attention as precursors for synthesis of nano sized semiconductors with various useful physical-chemical properties. In this work the results of the complexes aqua solutions’ optical properties monitoring are presented. It is known that SH-group of the L-cysteine and TGA can be oxidized by air oxygen spontaneously especially in neutral and alkaline medium so the studies was done at slightly acid conditions. The experiments in the Mn- L-cysteine system were performed at near physiological pH values ranged 5.5÷6.0 based on a previous theoretical consideration of possible ionic and molecular manganese and L-cysteine forms. The Mn-TGA- complexes were synthesized at pH = 6.0 and the Mn-citrate at pH=7.6.

A spectrophotometrical Ostromisslensky-Job’s method of continuous variations as commonly used procedure for determining the composition of stable complexes in solution was used. In this method, a series of solutions are prepared by mixing varying proportions of the metal and ligand in such manner that the sum of the total molar concentrations remained constant. The absorbance of each solution at a selective wavelength is then plotted against the mole fraction of either the ligand or metal. The ratio that corresponds to the mole fractions of the components in the complex will attain a maximum absorbance value.

Two total concentrations of the metal-ions plus the ligand constant equal to 0.05 M and 0.02 M were maintained. It was determined that though the Mn-L-cys mixtures were stable during more than a week, later tendency to cystin formation was observed. Absorbance spectra of the Mn-TGA solutions varied with time demonstrating rather slow complexation. The Mn-citrate complexes forming occurred most rapidly that observed by the variable absorbance spectra. The optical studies data treating by Ostromisslensky-Job’s method gives a possibility to reveal a clear peak in isomolar curves in Mn-citrate case only and concluded about the complexes forming in a stepwise fashion. The obtained results led to conclusion that despite the presence of three functional groups capable to the manganese ions chelating, both thiols exhibit weak complexation compared to citrate ions under the comparable conditions.
Occupational exposure and post-traumatic stress disorder: A rapid review
Authors: Van Eerd D. , Irvin E. , Harbin S. , Mahood Q. , Tiong M.
Published: February 2021

BACKGROUND: Post-Traumatic Stress Disorder (PTSD) can result from occupational exposures and poses a considerable burden to workers, their families, workplaces and to society in general. OBJECTIVE: Our objective was to conduct a rapid review of the literature to answer the question: “Which occupations have exposures that may lead to a PTSD diagnosis?” METHODS: A rapid review was conducted in six steps: review question development, literature search, study selection (inclusion/exclusion), study characterization, data extraction, and data synthesis. RESULTS: The search identified 3428 unique references which were reviewed to find 16 relevant studies in 23 articles. The articles revealed associations between PTSD and rescue workers (police, firefighters, etc.), health care professionals, transit drivers, and bank employees which seem well supported by the literature. Some studies also suggest potential associations with PTSD and construction and extraction, electricians, manufacturing, installation, maintenance and repair, transportation and material moving, and clerical workers. CONCLUSIONS: A rapid review of the peer-reviewed scientific literature of PTSD prevalence or treatment suggests many occupations have exposures that could be associated with PTSD. Occupational traumatic events were most often associated with PTSD diagnosis. More research is needed to better understand the association between occupation and PTSD.
ADA-SR: Activity detection and analysis using security robots for reliable workplace safety
Authors: Zhang Guangnan , Jing Wang , Tao Hai , Rahman Md Arafatur , Salih Sinan Q. , AL-Saffar Ahmed , Zhang Renrui
Published: February 2021

BACKGROUND: Human-Robot Interaction (HRI) has become a prominent solution to improve the robustness of real-time service provisioning through assisted functions for day-to-day activities. The application of the robotic system in security services helps to improve the precision of event detection and environmental monitoring with ease. OBJECTIVES: This paper discusses activity detection and analysis (ADA) using security robots in workplaces. The application scenario of this method relies on processing image and sensor data for event and activity detection. The events that are detected are classified for its abnormality based on the analysis performed using the sensor and image data operated using a convolution neural network. This method aims to improve the accuracy of detection by mitigating the deviations that are classified in different levels of the convolution process. RESULTS: The differences are identified based on independent data correlation and information processing. The performance of the proposed method is verified for the three human activities, such as standing, walking, and running, as detected using the images and sensor dataset. CONCLUSION: The results are compared with the existing method for metrics accuracy, classification time, and recall.
Pengaruh Kualitas Produk Terhadap Kepuasan Pelanggan Pada Kentucky Fried Chicken (KFC) Cabang Meruya
Authors: Sulistiani Sinta
Published: February 2021

Penelitian ini bertujuan untuk mengetahui pengaruh kualitas produk terhadap kepuasan pelanggan pada Kentucky Fried Chicken (KFC) Cabang Meruya. Metode yang digunakan adalah explanatory research dengan sampel sebanyak 96 responden. Teknik analisis menggunakan analisis statistik dengan pengujian regresi, korelasi, determinasi dan uji hipotesis. Hasil penelitian ini variabel kualitas produk diperoleh nilai rata-rata skor sebesar 3,410 dengan kriteria baik. Variabel kepuasan pelanggan diperoleh nilai rata-rata skor sebesar 3,836 dengan kriteria baik. Kualitas produk berpengaruh positif dan signifikan terhadap kepuasan pelanggan dengan nilai persamaan regresi Y = 9,021 + 0,860X, dan nilai koefisien korelasi 0,777 atau memiliki tingkat hubungan yang kuat dengan nilai determinasi 60,4%. Uji  hipotesis diperoleh signifikansi 0,000 < 0,05
Pengaruh Pendidikan Kewirausahaan Terhadap Minat Berwirausaha Siswa di Pondok Pesantren Al-Manar Cibeuteung Udik, Kecamatan Ciseeng, Kabupaten Bogor
Authors: Sirajuddin Sirajuddin , Jakariah Jakariah
Published: February 2021

Penelitian ini bertujuan untuk mengetahui pengaruh Pendidikan Kewirausahaan terhadap Minat Berwirausaha Siswa di Pondok Pesantren Al-Manar Cibeuteung Udik. Metode yang digunakan adalah explanatory research dengan sampel sebanyak 29 responden. Teknik analisis menggunakan analisis statistik dengan pengujian regresi, korelasi, determinasi dan uji hipotesis. Hasil penelitian ini variabel Pendidikan Kewirausahaan diperoleh nilai rata-rata skor sebesar 3,841 dengan kriteria baik. Variabel Minat Berwirausaha diperoleh nilai rata-rata skor sebesar 3,831 dengan kriteria baik. Pendidikan Kewirausahaan berpengaruh positif dan signifikan terhadap Minat Berwirausaha dengan nilai persamaan regresi Y = 11,971 + 0,686X, dan nilai koefisien korelasi 0,862 atau memiliki tingkat hubungan yang sangat kuat dengan nilai determinasi 74,4%. Uji  hipotesis diperoleh signifikansi 0,000 < 0,05.
A COMPARATIVE STUDY OF MIFEPRISTONE AND MISOPROSTOL VERSUS MISOPROSTOL ALONE IN INDUCTION OF LABOUR IN LATE INTRAUTERINE FETAL DEATH
Authors: Moond Shivpal , Banerjee K.P. , Arya Rakhi
Published: February 2021

Objective: To compare efficacy, safety and tolerance of combination of Mifepristone and Misoprostol versus Misoprostol alone in induction of labour in late intrauterine fetal death (>24 weeks).

Methods: This prospectively study included 160 women with late intrauterine fetal death (IUFD) after 24 weeks of gestation and divided the women randomly into two groups each containing 80 women. In Group-A : Mifepristone 200 mg single dose was given and after 24 hrs Tab Misoprostol (intravaginally) administered and repeated 4 hourly upto a maximum of 5 doses, while in Group-B : Only Tab Misoprostol administered intravaginally 4 hourly upto maximum 5 doses. Induction-delivery interval and number of doses of Misoprostol was calculated.   

Results: The mean induction-delivery interval in Group-A was 13.02 ± 3.74 hours and in Group-B was 16.09 ± 2.99 hours (p-value <0.0001). Mean doses of Misoprostol required in Group-A was 3.36 ± 1.08 hours and in Group-B was 4.32 ± 0.65 hours (p-value <0.0001).

Conclusion: Combination of Mifepristone and Misoprostol is more effective as comparison to Misoprostol in terms of induction-delivery interval and number of doses of misoprostol required.   

Keywords: IUFD, mifepristone, misoprostol, induction of labour, induction-delivery interval.
SAFETY REPORTING STUDY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
Authors: Mishra Monika
Published: February 2021

Background: The nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most frequently used drugs to treat pain and inflammation. Although NSAIDs are having enormous clinical use, but are not devoid of adverse drug reactions (ADRs) as peptic ulcer, gastritis, renal, neurological reactions etc.

Methods: Total 500 Orthopaedic out-patients of SIMS, Hapur were enrolled in the study to observe the risk of ADRs due to NSAIDs. All the ADRs were further analysed in relation to age, sex, types of drug and its pattern etc. The causality was analysed by using Naranjo’s Algorithm and severity was analysed by using the Hartwing and Siegel scale.

Results: In this study the incidence rate of the ADRs was around 5.6%. Among the 28 patients who had developed ADRs, a total 10 kinds of ADRs were observed. The reactions that affected the study subjects were gastritis, nausea, vomiting, abdominal Pain, diarrhoea, urticaria, pruritus, headache, rash, ankle oedema and dizziness. Majority (23 cases) of ADRs were mild in their severity and that 5 cases ADRs were moderate in nature. All the ADRs were treated symptomatically by using standard treatment protocols.

Conclusion: In this study, incidence of adverse reactions to nonsteroidal anti-inflammatory drugs was 5.60% and the most common implicated drug for the ADRs were Diclofenac sodium. Most of the adverse effects were mild and tolerable.

Keywords: Adverse drug reactions, Nonsteroidal anti-inflammatory drugs, Pharmacovigilance
Identifikasi Vertebrata Kelas Mamalia di Taman Satwa Taru Jurug Surakarta Sebagai Bahan Materi Pengembangan Video Pembelajaran Biologi SMA Kelas X
Authors: Fadhlianto Ibnu
Published: February 2021

The purpose of this study was to identify Vertebrate animals of the Mammal class, order artiodactyla, family Cervidae in the Jurug Surakarta taru Animal Park, develop interactive video media as a result of identification of vetebrata animals into learning media, know the quality of interactive video media based on assessment by material experts, media experts and biology teachers, and applications in learning. The research method uses an observation method by making direct observations of vertebrate species. The instrument for assessing the quality of interactive video media is based on material aspects and presentation aspects, with a qualitative descriptive analysis design. The results of this study indicate that in Taru Jurug Animal Park Surakarta there are 3 species of animals namely Cervus unicolor, Cervus timorensis, Axis-axis and all three have been identified. Research on the identification of vertebrate animals, especially the mammalian class, order artiodactyla, and the cervidae family can be used for the preparation of interactive video media with material on Biodiversity at the level of genes and species. The quality of interactive video media in terms of material aspects, presentation, and language. Assessment of material experts obtained a percentage of 90.9% so that it was categorized as very valid, media experts obtained a percentage of 88.5% so it was categorized as very valid, biology teacher Veteran 1 Sukoharjo High School obtained a percentage of 92.5% so it was categorized as very valid and biology teacher Nguter 1 Public High School obtained a percentage of 97.5% so it is categorized as very valid. Based on this, it can be concluded that this interactive video media is worthy of being used by teachers as one of the learning media about Biodiversity at the level of genes and species.
Arsitektur Sistem Informasi Akademik Perguruan Tinggi Swasta Menggunakan EAP
Authors: Fatoni Fatoni , Supratman Edi , Antoni Darius
Published: February 2021

Universities in Indonesia already have academic information systems. This university in developing its academic information system is carried out individually according to conditions and needs. Currently there are no guidelines in providing direction for the planning, development, implementation and service of academic information systems based on information and communication technology in universities. In addition to this, it is based on the planning and development of an academic information system which is what will be planned and developed and how its development guidelines are not yet available. The purpose of this study is to provide guidance in building academic information systems at private universities that can be applied in South Sumatra Province. This goal needs to be done because in general the academic information system business processes and services as well as the need for information in each university have in common namely the acceptance of new students, academic management and academic release. The result of the research is an academic information system architecture as a guideline in planning the development of an academic information system according to the conditions of private universities in South Sumatra Province. This study uses the EAP method with the steps of activities including planning initiation, business modeling and survey of current institutions, systems and technologies, data architecture and application architecture. The results of this study are a guide in building a system in the form of an academic information system architecture that can be applied to private universities in Indonesia especially South Sumatra Province.This study uses the EAP / Enterprise Architecture Planning method with activity steps including planning initiation, business modeling and institutional surveys, current systems and technology, data architecture and application architecture.
Ensino de Língua Estrangeira no Brasil: Interfaces da abordagem de conteúdo e linguagem no ensino remoto
Authors: Silva Ana Lúcia Farias da , Ramos Teresa Cristina Giarolla , Sodré Rachel Fontes
Published: February 2021

O presente artigo tem como objetivo descrever o desenvolvimento do processo de ensino–aprendizagem de Língua Estrangeira, com o uso da abordagem CLIL (Ensino Integrado de Conteúdo e Linguagem) no ensino do Inglês, no âmbito de um Programa Bilíngue, dentro de um contexto emergencial de Ensino Remoto. Buscamos refletir, também, acerca da adequação das ferramentas tecnológicas no processo de ensino de Língua Estrangeira – especificamente da Língua Inglesa – para uma determinada faixa etária, bem como avaliar a elaboração e a adaptação de materiais, atividades e abordagens pedagógicas à realidade do Ensino Remoto durante o período de isolamento. Para tal reflexão, nossa análise propõe-se a apontar possibilidades e limitações, tanto da abordagem CLIL (Ensino Integrado de Conteúdo e Linguagem), como da modalidade do ensino a distância para a faixa etária observada. Deste modo, além de apresentar o que foi realizado durante a pesquisa, pretendemos refletir sobre possíveis caminhos e contribuir com boas práticas que tornem o processo do Ensino de Língua Inglesa mais significativo e proficiente, dentro da modalidade EaD (Educação a Distância).Defendemos nesta pesquisa a busca por estratégias em um formato digital , por um Ensino de Língua Estrangeira, que se desenvolva de forma mais natural e motivador, bem como a necessidade de políticas públicas voltadas a uma educação pós-pandemia do COVID-19, no sentido da ludicidade e inclusão, visando o desenvolvimento de competências e habilidades do aluno, desde o Ensino Fundamental, transformando a informação em conhecimento.
The relationship between high school GPA and information literacy pre and post-test scores
Authors: Shannon Eric
Published: February 2021

Although many studies explore the effect of library instruction on information literacy test scores, there are far fewer studies exploring the relationship between high school Grade Point Average (GPA) and scores on information literacy pre- and post-tests of first year college students. This research study compares the scores of three cohorts of Franklin Pierce University students--honors students, Center Scholars (students with a cumulative high school GPA of below 2.5) and Average GPA students --on an information literacy pre-test administered in the first two weeks of the fall, and a similar post-test administered after students have attended a library instruction session. The results of this study show a relationship between high school GPA and pre-test scores and reveal an even stronger relationship between high school GPA and scores on the post-test, with honors students attaining the highest scores and Center Scholars the lowest. This article proposes explanations for these results as well as recommendations for addressing the test score disparities between these three cohorts.
Evaluating the Effect of Asymmetric Cross-section in Free Vibration and Bending Analysis Results of FG Sandwich Beam by Proposing Simple Efficient Element
Authors: Yaghoobi Majid , Sedaghatjo Mohsen , Alizadeh Reyhaneh , KARKON Mohammad
Published: February 2021

In this paper, the asymmetric effect of the cross-section on the free vibration and bending analysis of FG sandwich beams are evaluated. For this purpose, a simple, efficient element is formulated. The new element is created based on the Timoshenko beam theory. The third- and second-order polynomials will be used for vertical displacement and rotation fields, respectively. The proposed formulation will be written based on satisfying the equilibrium equation. Satisfying the equilibrium equation of the Timoshenko beam, in addition to increasing element efficiency, will reduce the number of nodal unknowns. Several benchmark tests with different boundary conditions are used for thin and thick beams to prove the efficiency of the proposed element. The responses of the good elements of other researchers have been used for comparison. Numerical tests prove the rapid convergence rate and high accuracy of the proposed element in free vibration and bending analysis of the beams with various cross-section types and different boundary conditions. The pinned-sliding support conditions for the beam are used to evaluate the asymmetric effect of the cross-section. The use of asymmetric cross-sections creates additional axial displacements and intensifies the deflection of the beam under the lateral load. By increasing the asymmetry, the additional axial displacement and vertical displacement increase. These additional deflections for thin beams are more than thick ones. Also, asymmetry results in increasing the natural frequencies of beams. In the free vibration analysis, the effect of asymmetry on thick beams is more than thin ones.
«Fort males paraules, desonestes e injurioses». L’insult en la vida política d’una ciutat medieval
Authors: Juncosa Bonet Eduard
Published: February 2021

Abstract Apart from the considerations set out by jurists, moralists or sarcastic poets about cursing in the late Middle Ages, the main purpose of this article is to analyse the use of the insults («bad words, dishonest and offensive»), through the direct study of municipal sources and court proceedings, in the social and political life of a Catalan city within this period, focusing on the analysis of the insult’s variants, the situations where it was used, those targeted by it and some of its resulting consequences at every turn. Despite the frequent attempts to restrict or forbid its usage so as not to «stray away from good morals», blasphemy and derision became a rather common means of attack, predominantly in lawsuits and in convulsive contexts. Nevertheless, the sanctions imposed on offenders varied extensively, ranging from a simple request for pardon to fines, loss of rights, and even punishment by death.

Keywords: Insults, Morality, Municipal Power, Tarragona, Late Middle Ages.
The organizational and economic components of investment support in agricultural enterprises activity
Authors: Svinous N.
Published: February 2021

In this article we systematized the components of organizational and economic support of investment activity in agricultural enterprises as structured system of goal-oriented system for capitalization and modernization of production potential.The concept of investment and investment process in agricultural production was specified, their features in the researched branch were defined.
The author considers the development of investment activity of the enterprise as a qualitative evolution, which involves modernization, renewal of production capacity, increasing its productivity and is accompanied by dynamic changes in significant parameters of the enterprise.It was proposed to consider the system of mutually agreed instruments of influence on the participants of the investment process under the organizational and economic support of investment activity in agricultural enterprises, which promote harmonization of their economic interests and ensure growth of its value (capitalization) and qualitative improvement of production potential.
The following elements were pointed out as components of organizational and economic support of investment activity in agricultural enterprises:
object and subject;
goals and management tasks;
criterion of efficiency;
methods and tools of regulation which are implemented in the form of tools (levers).
The criterion of the organizational levers block efficiency of investment support system was substantiated - growing dynamics of investment intakes at constant preservation of all participants interests and economic levers - positive influence on set of industrial, economic, ecological and social relations at the enterprise level.It was highlighted that in order to increase the effectiveness of organizational and economic support components of agricultural enterprises investment activities, it is advisable to take into account the economic interests of all its participants.
It was offered to consider as the main efficiency criterion of organizational and economic support system in investment activity of agricultural enterprises to increase the value of the enterprise (capitalization) and qualitative improvement of production potential, which will strengthen the competitive position in target markets.The functions of the components of organizational and economic support of investment activity: motivational, prohibitive and compensatory were systematized.
Keywords: investment activity, organizational and economic tools, agricultural enterprises, subjects and objects of management.
L’erogazione di prestazioni sanitarie in telemedicina
Authors: Burrai Francesco , Gambella Margherita , Scarpa Angelica
Published: February 2021

As a consequence of the Sars-CoV2 pandemic, the role of telemedicine in the healthcare sector was reviewed in order to ensure continuity of care and to contain infections. This new frontier involves professionals, caregivers, patients and can be applied in various fields, such as surgery, specialist visits, follow-ups, home care, health education, prevention and monitoring. Despite privacy may seem a deterrent for the implementation of this new goal in the healthcare sector, the community and the national legislation both provide rules to protect individuals and the community. This innovative method of assistance brings with it limits that must not detract attention from the great possibilities arising from the use of telemedicine.
Bacterial endophytes: An agroecological alternative in the growth promotion and plant health management of cabbage leaf (Brassica oleracea var. acephala)
Authors: Silva Clayton dos Santos , Araújo Romário Guimarães Verçosa de , Lima Jessé Rafael Bento de , Sousa Luiggi Canário Cabral e , Silva Paula Cibelly Vilela da , Santos Tania Marta Carvalho dos , Costa Jakes Halan de Queiroz , Da Silva João Manoel
Published: February 2021

Among the most economically significant agricultural crops, the species of the Brassicaceae family stand out as one of the most popular in human food. Cabbage leaf (Brassica oleracea var. acephala) is an essential ingredient in many regional dishes and is an excellent nutritional source for children, young and old. However, Brazilian production has been suffering from the incidence of pests and diseases that affect the crop, being the black rot of the cruciferous (BRC), the main cause of economic losses of its producers. Given this context, the objective is to build a theoretical framework by reviewing the literature on the agroecological management of BRC in cabbage leaf, based on the contribution of scientific knowledge to the preservation of agrobiodiversity in rural and traditional family communities.
Optimization of Oil Adsorption Capacity by Aerogel Powder Synthesized Using Emulsion Droplets as Micro-reactors in Ambient Conditions from Sodium Silicate as Precursor
Authors: Cho Young-Sang , Sung Sohyeon , Woo Seung Hee , Kim Young Seok
Published: February 2021

In this study, silica aerogel particles were synthesized from emulsion droplets as micro-reactors at room temperature under ambient pressure. An economical precursor, sodium silicate, was used as the starting material for silica, and an emulsification technique was applied to form droplets in continuous phase. By controlling the composition of the dispersed phase using ammonium hydroxide, the effect of pH on the morphologies of the final aerogel particles was studied by SEM observation. As a demonstrative application, hydrophobic silica aerogel particles were produced by modification using a silane coupling agent, for oil adsorption. The amount of oil adsorbed by the aerogel particles was optimized by adjusting the concentration of precursors in the emulsion droplets, the composition of the dispersed phase, and the concentration of the coupling agent during surface treatment of the particles. The resulting aerogel particles were characterized using BET, TGA, and the contact angle of water droplets after modification using silane coupling agents with different carbon numbers. The optimized value of adsorbed silicone oil (100 CS) was measured to be about 250 % relative to the weight of the aerogel particles. For comparison, other types of porous silica particles were also prepared from emulsion-assisted self-assembly routes to quantify the amount of adsorbed oil.
POLÍTICAS E PRÁTICAS PEDAGÓGICAS NA PERSPECTIVA DA INCLUSÃO
Authors: Nakanichi Claudia , Silva Michael Santos , Ribeiro Débora Inácia , Bussolotti Juliana Marcondes
Published: February 2021

O presente artigo aborda a interface entre as políticas públicas e as práticas pedagógicas na perspectiva da inclusão na sala de aula por meio da construção de um levantamento de pesquisas correlatas. O escopo deste estudo foi investigar as práticas pedagógicas inclusivas em sala de aula regular do Ensino Fundamental. A fundamentação teórica pautou-se nos autores expoentes da área: Mantoan e Prieto (2006), Mantoan (2003, 2013), Prieto (2007), Glat et al. (2006), Tardif (2007). A investigação adotou a abordagem qualitativa com objetivo descritivo a partir do procedimento da análise das pesquisas correlatas com consulta nas bases de dados: PePSIC, IBICT, Periódicos CAPES e SciELO. Os resultados apontam para a necessidade de uma formação que concilie teoria e prática e um redesenhar da prática pedagógica, destaca, ainda, o distanciamento existente entre o ensino comum e a Sala de Recursos Multifuncionais, além da melhoria da qualidade do processo de inclusão dos alunos com DI (Deficiência Intelectual) e ampliação dos conhecimentos teóricos e práticos dos professores acerca da educação inclusiva. Pôde-se concluir, diante das pesquisas correlatas analisadas, que um repensar na prática pedagógica e uma superação de preconceitos com relação aos alunos com deficiência em sala de aula regular são essenciais em prol de um efetivo processo educativo inclusivo.
Hypertension and COVID-19: Ongoing Controversies
Authors: Tadic Marijana , Saeed Sahrai , Grassi Guido , Taddei Stefano , Mancia Giuseppe , Cuspidi Cesare
Published: February 2021

Coronavirus disease 2019 (COVID-19) has become a worldwide pandemic responsible for millions of deaths around the world. Hypertension has been identified as one of the most common comorbidities and risk factors for severity and adverse outcome in these patients. Recent investigations have raised the question whether hypertension represents a predictor of outcome in COVID-19 patients independently of other common comorbidities such as diabetes, obesity, other cardiovascular diseases, chronic kidney, liver, and pulmonary diseases. However, the impact of chronic and newly diagnosed hypertension in COVID-19 patients has been insufficiently investigated. The same is true for the relationship between blood pressure levels and outcomes in COVID-19 patients. It seems that the long discussion about the impact of angiotensin-converting enzyme inhibitors (ACEI) and blockers of angiotensin I receptors (ARB) on severity and outcome in COVID-19 is approaching an end because the large number of original studies and meta-analyses discarded the initial findings about higher prevalence of ACEI/ARB use in patients with unfavorable outcomes. Nevertheless, there are many controversies in the relationship between hypertension and COVID-19. The aim of this review article is to provide a clinical overview of the currently available evidence regarding the predictive value of hypertension, the effect of blood pressure levels, the impact of previously known and newly diagnosed hypertension, and the effect of antihypertensive therapy on the severity and outcomes in COVID-19 patients.
Case Report: Hyperbilirubinemia in Gilbert Syndrome Attenuates Covid-19-Induced Metabolic Disturbances
Authors: Al-kuraishy Hayder M. , Al-Gareeb Ali I. , Abdullah Saleh M. , Cruz-Martins Natália , Batiha Gaber El-Saber
Published: February 2021

Gilbert syndrome (GS) is a liver disorder characterized by non-hemolytic unconjugated hyperbilirubinemia. On the other hand, Coronavirus disease 2019 (Covid-19) is a recent viral infectious disease presented as clusters of pneumonia, triggered by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Little is known on the association between SARS-CoV-2 and GS, despite different studies have recently stated a link between hyperbilirubinemia and SARS-CoV-2 severity. In this case-report study we described a 47-year-old man, a known case of GS since the age of 4, presented to the emergency department with fever (39.8°C), dry cough, dyspnea, headache, myalgia, sweating and jaundice diagnosed with Covid-19-induced pneumonia. Interestingly, GS patient exhibited a rapid clinical recovery and short hospital stay compared to other SARS-CoV-2 positive patient, seeming that hyperbilirubinemia may exert a protective effect of against Covid-19 induced-cardiometabolic disturbances. Data obtained here underlines that the higher resistance against Covid-19 evidenced by the GS patient seems to be due to the antioxidant, anti-inflammatory, and antiviral effects of unconjugated bilirubin.
Integrated Microbiome and Metabolome Analysis Reveals a Positive Change in the Intestinal Environment of Myostatin Edited Large White Pigs
Authors: Pei Yangli , Chen Chujie , Mu Yulian , Yang Yalan , Feng Zheng , Li Bugao , Li Hua , Li Kui
Published: February 2021

Myostatin (MSTN) functional inactivation can change the proportion of lean meat and fat content in pigs. While both genotype and microbial composition are known to affect the host phenotype, so far there has been no systematic study to detect the changes in the intestinal microbial composition and metabolome of MSTN single copy mutant pigs. Here, we used 16S rDNA sequencing and metabolome analysis to investigate how MSTN gene editing affects changes in the microbial and metabolome composition in the jejunum and the cecum of Large White pigs. Our results showed that Clostridium_sensu_stricto_1, Bifidobacterium, Lachnospiraceae_UCG-007, Clostridium_sensu_stricto_6, Ruminococcaceae_UCG-002, and Ruminococcaceae_UCG-004 were significantly upregulated; while Treponema_2 and T34_unclassified were significantly downregulated in the jejunum of MSTN pigs. Similarly, Phascolarctobacterium, Ruminiclostridium_9, Succinivibrio, Longibaculum, and Candidatus_Stoquefichus were significantly upregulated, while Barnesiella was significantly downregulated in the cecum of MSTN pigs. Moreover, metabolomics analysis showed significant changes in metabolites involved in purine, sphingolipid and tryptophan metabolism in the jejunum, while those associated with glycerophospholipid and pyrimidine metabolism were changed in the cecum. Spearman correlation analysis further demonstrated that there was a significant correlation between microflora composition and metabolites. Our analyses indicated the MSTN editing affects the composition of metabolites and microbial strains in the jejunum and the cecum, which might provide more useable nutrients for the host of MSTN± Large White pigs.
Exploring the Therapeutic Potenital of the Leaderless Enterocins K1 and EJ97 in the Treatment of Vancomycin-Resistant Enterococcal Infection
Authors: Reinseth Ingvild , Tønnesen Hanne H. , Carlsen Harald , Diep Dzung B.
Published: February 2021

The membrane-bound protease Eep is an important virulence factor in pathogenic enterococci. The protein is involved in stress response via the RIP pathway which is crucial for pathogenic enterococci to evade host immune attacks during infection. Eep serves also as a receptor for the bacteriocins enterocin K1 and enterocin EJ97. The bacteriocins kill Enterococcus faecium and E. faecalis, respectively, and their antibiotic resistant derivatives including vancomycin resistant enterococci (VRE). This functional duality of Eep makes these two enterocins very promising as options in the prospective treatment of enterococcal infections because wildtype enterococcal cells (with an intact Eep) are sensitive to the bacteriocins while bacteriocin-resistant-mutants (without a functional Eep) become less virulent. As a first step to explore their therapeutic potential in the treatment of systemic enterococcal infections, we investigated the compatibility of the bacteriocins with human blood, and the phenotypic changes of eep-mutants toward different stress conditions. We found that the bacteriocins were compatible with blood, as they did not cause haemolysis and that the bacteriocins retained most of their antibacterial effect when incubated in blood. The bacteriocins were autoclavable which is a crucial criterium for the development of parenteral administration. Eep-mutants, which became resistant to the bacteriocin were, as expected, less capable to withstand stress conditions such as exposure to lysozyme and desiccation. Further, their ability to chain, a trait implicated in niche adaptation as well as being necessary for genetic transfer via conjugation, was also severely affected. Together, these results indicate that the bacteriocins are promising for treatment of VRE infection.
Trends in Haptic Communication of Human-Human Dyads: Toward Natural Human-Robot Co-manipulation
Authors: Jensen Spencer W. , Salmon John L. , Killpack Marc D.
Published: February 2021

In this paper, we analyze and report on observable trends in human-human dyads performing collaborative manipulation (co-manipulation) tasks with an extended object (object with significant length). We present a detailed analysis relating trends in interaction forces and torques with other metrics and propose that these trends could provide a way of improving communication and efficiency for human-robot dyads. We find that the motion of the co-manipulated object has a measurable oscillatory component. We confirm that haptic feedback alone represents a sufficient communication channel for co-manipulation tasks, however we find that the loss of visual and auditory channels has a significant effect on interaction torque and velocity. The main objective of this paper is to lay the essential groundwork in defining principles of co-manipulation between human dyads. We propose that these principles could enable effective and intuitive human-robot collaborative manipulation in future co-manipulation research.
Non-Invasive Radiomics Approach Predict Invasiveness of Adamantinomatous Craniopharyngioma Before Surgery
Authors: Ma Guofo , Kang Jie , Qiao Ning , Zhang Bochao , Chen Xuzhu , Li Guilin , Gao Zhixian , Gui Songbai
Published: February 2021

Purpose

Craniopharyngiomas (CPs) are benign tumors, complete tumor resection is considered to be the optimal treatment. However, although histologically benign, the local invasiveness of CPs commonly contributes to incomplete resection and a poor prognosis. At present, some advocate less aggressive surgery combined with radiotherapy as a more reasonable and effective means of protecting hypothalamus function and preventing recurrence in patients with tight tumor adhesion to the hypothalamus. Hence, if a method can be developed to predict the invasiveness of CP preoperatively, it will help in the development of a more personalized surgical strategy. The aim of the study was to report a radiomics-clinical nomogram for the individualized preoperative prediction of the invasiveness of adamantinomatous CP (ACPs) before surgery.

Methods

In total, 1,874 radiomics features were extracted from whole tumors on contrast-enhanced T1-weighted images. A support vector machine trained a predictive model that was validated using receiver operating characteristic (ROC) analysis on an independent test set. Moreover, a nomogram was constructed incorporating clinical characteristics and the radiomics signature for individual prediction.

Results

Eleven features associated with the invasiveness of ACPs were selected by using the least absolute shrinkage and selection operator (LASSO) method. These features yielded area under the curve (AUC) values of 79.09 and 73.5% for the training and test sets, respectively. The nomogram incorporating peritumoral edema and the radiomics signature yielded good calibration in the training and test sets with the AUCs of 84.79 and 76.48%, respectively.

Conclusion

The developed model yields good performance, indicating that the invasiveness of APCs can be predicted using noninvasive radiological data. This reliable, noninvasive tool can help clinical decision making and improve patient prognosis.
Rectovaginal Fistula With Double Vagina and Anastomotic Stenosis: A Case Report Following Rectal Cancer Surgery
Authors: Li Qiwei , Sun Jianhua , Yin Lu , Ji Fu
Published: February 2021

Rectovaginal fistula (RVF) occurs as a result of abnormal epithelialized connections between the rectum and vagina. Rectal cancer surgery remains the major cause of RVF. Here, we report a rare postoperative complication in which a patient with a double uterine and vagina received RVF following rectal cancer surgery. The patient received radiotherapy and developed rectal anastomotic stenosis leading to scar hyperplasia around the fistula, making repair difficult. Complex RVF is prone to release, which despite the multitude of procedures and treatments reported, optimal strategies remain controversial. Our previous studies showed how the use of rectal mucosal advancement flap (RMAF) with transanal endoscopic surgery (TES) can repair mid-low RVF. We successfully repaired RVF and rectal anastomotic stenosis with staging TES in this complex case. This highlights the safety and utility of TES treatment for complex RVF. Further studies are now required to confirm its effectiveness.