bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Pengetahuan dan Kepatuhan Protokol Kesehatan 3M dengan Kejadian Covid-19 di Puskesmas Pemurus Dalam Tahun 2021
Authors: Baylina Syellin Ivasga , Heriyani Farida , Hayatie Lisda , Noor Meitria Syahadatina , Edyson Edyson
Published: March 2023

Abstract: The case of COVID-19 continues to increase. Health protocols are being promoted by the government in an effort to prevent the spread of COVID-19. The purpose of this study was to analyze the relationship between knowledge and adherence to the 3M health protocol with the incidence of COVID-19 in Banjarmasin City. This study used an analytic observational method in the form of a case control in Pemurus Dalam Public Health Center in Banjarmasin City using a questionnaire distributed via a google form link, the data were analyzed using the chi square test. The results showed that subjects in the case group 43% had poor knowledge and 12% did not comply with health protocols when compared to the control group which only had a little bad knowledge (11%) and more who obeyed health protocols (91%). The conclusion of this study is that there is a significant correlation (p value < 0,050) between knowledge and compliance with the 3M health protocol with the incidence of COVID-19 in Pemurus Dalam Community Health Center in 2021. Keywords: knowledge, compliance, health protocol, incidence, COVID-19 Abstrak: Jumlah kasus COVID-19 terus meningkat. Protokol kesehatan sedang digalakkan oleh pemerintah dalam upaya pencegahan penyebaran COVID-19. Tujuan penelitian ini untuk menganalisis hubungan antara pengetahuan dan kepatuhan protokol kesehatan 3M dengan kejadian COVID-19 di Kota Banjarmasin. Penelitian ini menggunakan metode observasional analitik berupa case control di Puskesmas Pemurus Dalam Kota Banjarmasin dengan menggunakan kuesioner yang disebarkan melalui link google form, data dianalisis menggunakan uji chi square. Hasil penelitian menunjukkan bahwa subjek pada kelompok kasus 43% memiliki pengetahuan kurang dan 12% tidak mematuhi protokol kesehatan jika dibandingkan dengan kelompok kontrol yang hanya memiliki sedikit pengetahuan buruk (11%) dan lebih banyak yang mematuhi protokol kesehatan (91%). Kesimpulan dari penelitian ini adalah terdapat hubungan yang signifikan (p value < 0,050) antara pengetahuan dan kepatuhan protokol kesehatan 3M dengan kejadian COVID-19 di Puskesmas Pemurus Dalam Tahun 2021. Kata-kata kunci: pengetahuan, kepatuhan, protokol kesehatan, kejadian, COVID-19
Literature Review: Pengaruh Pemberian Mecobalamin terhadap Perbaikan Klinis Pasien dengan Neuropati Perifer
Authors: Christanty Dyah Septy Tri , Pambudi Pagan , Nurikhwan Pandji Winata , Dafif Muhammad Welly , Bakhriansyah Mohammad
Published: March 2023

Abstract: Peripheral neuropathy is a disorder of peripheral nerve function. It could be classified into 3 namely, mononeuropathy, mononeuropathy multiplex, and polyneuropathy. Mecobalamin is an active analog of vitamin B12 used in the treatment of peripheral neuropathy. It is used as an analgesic and increases nerve conduction provide neuronal protection by promoting the regeneration and maintenance of nerve cell function. This literature review was made to determine whether the administration of mecobalamin could provide clinical improvement in peripheral neuropathy patients. The data used was obtained by searching articles on PubMed, Science Direct, and Google Scholar. The articles used were articles with the year of publication from 2011-2021. A total of 6 articles would be reviewed after the search and selection were processed. The 6 existing articles showed that mecobalamin had an influence on the clinical improvement of peripheral neuropathy caused by entrapment, diabetes, heredity, and inflammation. The clinical improvement was a decrease in pain scores, decreased range of motion, grip strength, and reduced weakness in the distribution of affected nerves. Keywords: vitamin B12, mecobalamin, peripheral neuropathy Abstrak: Neuropati perifer merupakan suatu kondisi gangguan pada fungsi saraf perifer. Neuropati perifer dapat dibagi menjadi 3 jenis yaitu, mononeuropati, mononeuropati multipleks dan polineuropati. Mecobalamin merupakan bentuk analog aktif vitamin B12 yang digunakan pada terapi neuropati perifer. Mecobalamin dapat digunakan sebagai analgetik, untuk meningkatkan konduksi saraf serta menjadi proteksi neuronal dengan mendorong regenerasi dan pemeliharaan fungsi sel saraf. Literature review ini dibuat untuk mengetahui apakah pemberian mecobalamin dapat memberikan perbaikan klinis pada pasien neuropati perifer. Data yang digunakan dalam kajian ini didapatkan dengan melakukan penelurusan artikel di PubMed, Science Direct, dan Google Scholar. Artikel yang digunakan adalah artikel dengan tahun publikasi dari 2011-2021. Sebanyak 6 artikel akan dikaji setelah proses pencarian dan seleksi. Dari 6 artikel yang ada, semuanya menunjukan bahwa mecobalamin memiliki pengaruh dalam perbaikan klinis neuropati perifer yang disebabkan oleh entrapment, diabetik, herediter dan peradangan. Perbaikan klinis tersebut diantaranya adalah penurunan skor nyeri, penurunan keterbatasan gerak, kekuatan menggenggam, dan mengurangi rasa kelemahan pada bagian yang terdistribusi oleh saraf yang terganggu. Kata-kata kunci: vitamin B12, mecobalamin, neuropati perifer
Literature Review: Hubungan Kadar Hemoglobin dengan Nilai VO2 Maks pada Atlet
Authors: Wulandari Dina Ananda , Kaidah Siti , Huldani Huldani
Published: March 2023

Abstract: Sport is a form of physical activities that is carried out by a programm and measurable manner that aim of achieving physical fitness and achievement. To achieve the optimal athlete achievement, good hemoglobin levels and VO2 max are necessary because they both a critical role in providing energy and transporting oxygen to tissues when doing competitions. This literature review aims to analyze the relationship between hemoglobin levels and VO2 max in athletes from 16 literatures. The reviewed articles were obtained through the Google Scholar and PubMed databases. The articles included are in English and Indonesian with the publication year 2011-2021. Based on the 16 literatures, there were differences in results, 93.75% of them showed a relationship between hemoglobin levels and VO2 max in athletes while the rest showed no significant relationship. The difference in results is supposed to be related to differences in several influencing factors, such as gender, type of sport, physical activity, duration and intensity of exercise, body composition, individual variation, and sports anaemia. Keywords: correlations, hemoglobin, VO2 max, athletes Abstrak: Olahraga merupakan bentuk aktivitas fisik yang dilakukan secara terprogram dan terukur dengan tujuan tercapainya kebugaran jasmani dan prestasi. Untuk mencapai prestasi atlet secara optimal, kadar hemoglobin dan nilai VO2 maks yang baik diperlukan karena keduanya berperan dalam penyedia energi serta pengangkut oksigen ke jaringan ketika melakukan pertandingan. Literature review ini bertujuan untuk menganalisis hubungan antara kadar hemoglobin dengan nilai VO2 maks pada atlet dari 16 literatur. Artikel yang direview diperoleh melalui database jurnal kedokteran, yaitu Google Scholar dan PubMed. Artikel yang disertakan  menggunakan bahasa Inggris dan Indonesia dengan tahun publikasi 2011-2021. Berdasarkan 16 literatur, ditemukan perbedaan hasil, 93,75% diantaranya memperlihatkan hubungan antara kadar hemoglobin dengan nilai VO2 maks pada atlet sedangkan sisanya memperlihatkan tidak ada hubungan signifikan. Perbedaan hasil ini diduga berkaitan dengan adanya perbedaan pada beberapa faktor yang berpengaruh, seperti jenis kelamin, jenis cabang olahraga, aktivitas fisik, durasi dan intensitas latihan, komposisi tubuh, variasi individu, serta sport anaemia. Kata-kata kunci: hubungan, hemoglobin, VO2 maks, atlet
MANIFESTASI KLINIS DAN PROFIL HEMATOLOGI BALITA DENGAN DIARE AKUT DI RSD IDAMAN BANJARBARU TAHUN 2020-2021
Authors: Shabella Gita , Ringoringo Harapan Parlindungan , Noor Meitria Syahadatina
Published: March 2023

Acute diarrhea is an increase in stool discharge with a softer or more liquid consistency than usual, occurring at least 3 times in 24 hours with or without mucus and blood lasting <14 days. The purpose of this study is to find out the clinical manifestations, hematology profile, and examination of feces of children under five at Idaman Banjarbaru Hospital in 2020-2021. The methods used in this study are descriptive retrospective. Data retrieval techniques are done purposive sampling by paying attention to inclusion and exclusion criteria. The study sample included 35 children with clinical manifestation data and a complete hematological profile. The results showed the most age in the group of 12-36 months with a percentage of 60%. By gender there were 21 children (64.86%) male. The study concluded that 27 children (77.14%), were in vomiting in 26 children (74.28%). The majority with normal leukocyte levels with a percentage of 22 (62.85%) children, hemoglobin levels within normal limits are as many as 25 children (71.43%).
LITERATURE REVIEW: PERBEDAAN KADAR HEMATOKRIT PADA ATLET DAN BUKAN ATLET
Authors: Ramadhina Adira Zahwa , Kaidah Siti , Huldani Huldani
Published: March 2023

In athletes, it is very important to maintain a good performance from start to finish, especially at certain times. The use of oxygen and blood flow will increase to meet the oxygen needs of the muscles during exercise. When there is increasing oxygen demand happens in the body, there will be stimulation of erythropoietin to produce red blood cells in the bone marrow, which is affect to the haematocrit value. The purpose of this literature review is to make a distinction about the difference in haematocrit levels in athletes and non-athletes. The reviewed articles were obtained through the Google Scholar and PubMed databases. The articles included are in English and Indonesian, published in 2011-2021. Different results were found between the studies appraised in this review, this could be due to differences in several factors such as duration, frequency, type of exercise, dehydration, gender, and nutritional intake
LITERATURE REVIEW: PERBANDINGAN EFEKTIVITAS TERAPI ULTRASOUND DIATHERMY DAN MICROWAVE DIATHERMY TERHADAP MOBILTAS PASIEN OSTEOARTRITIS LUTUT
Authors: Tsauri Ahmad Sofian , Siddik Muhammad , Sanyoto Didik Dwi , Putranto Bambang Dwi , Putera Husna Dharma
Published: March 2023

Osteoarthritis is a type of arthritis that is commonly found in the elderly and is the leading cause of pain in patients with knee osteoarthritis. Non-pharmacological therapy, such as ultrasound diathermy and microwave diathermy, is one of the treatment options. Thermal therapy and function in tissue regeneration, improving metabolic processes, and lowering inflammation of knee OA are two therapies that have something in common. The aim of the review is to compare the effectiveness of US and MWD on knee OA patients' mobility. analysis was carried out A literature study was conducted using several electronic medical journal databases, including PubMed-NCBI, ProQuest, Science Direct, and Google Scholar. Articles in English and Indonesian published between 2011–2021 qualify for inclusion. In this literature review, ten articles were used. The results of the review found that US and MWD have the same effectiveness in improving body function or mobility in knee OA patients. Six of the seven US articles showed effective results in improving the functional capacity of the body or mobility of knee OA. The three MWD articles also showed effective results in increasing the functional capacity of the body or the mobility of knee OA. Based on the average score of body functional parameters with WOMAC, TUGT, and stiffness, it can be concluded that MWD therapy is better than US in improving mobility function of knee OA
LITERATURE REVIEW: KOMPONEN NYERI NEUROPATIK PADA NYERI PUNGGUNG BAWAH
Authors: Yudiantara Nasywa Maharani , Pambudi Pagan , Husairi Ahmad , Dafif Muhammad Welly , Marisa Dona
Published: March 2023

Low back pain is a very common health problem and can affect the quality of life. Pain that arises in low back pain can be either nociceptive pain or neuropathic pain. This literature review discusses the neuropathic pain component of low back pain.  This review uses a narrative review method. The articles were obtained from keyword searches in the Science Direct, PubMed, and ProQuest databases with a publication range of 2011-2021 in Indonesian or English, and research on the components of neuropathic pain in low back pain. Of the eight articles included in this literature review, the prevalence of neuropathic pain in low back pain was 2.8% - 65.3%. Neuropathic pain can be ruled out using LANSS, DN4, and PDQ. Low back pain with neuropathic pain had symptoms of burning (34.58% - 82.9%), pinpricks (31.77% - 78%), tingling (32.71% - 84.8%), numbness (42.05% - 97%), electric shock (38.97% - 78%), itching (16.82% - 42.4%), cold sensation (12.15% - 48.5%), allodynia (19.62% - 85.4%), 61% hyperalgesia, 14.6% autonomic dysfunction, 100% had dysesthesia, and 100% experienced a decrease in tenderness/prickling. Radicular low back pain is often caused by L5 or S1 root compression and rarely L4. Neuropathic low back pain can be based on an assessment of the symptom profile. Associated risk factors are older age, being a female, greater anthropometric status, the habit of drinking alcohol, smoking, and history of previous lumbar, abdominal or pelvic surgery
HUBUNGAN TEKANAN DARAH DENGAN FUNGSI KOGNITIF PADA GERIATRI DI RSUD ULIN BANJARMASIN
Authors: Rosa Diva Aurellia , Pambudi Pagan , Husairi Ahmad , Dafif Muhammad Welly , Marisa Dona
Published: March 2023

One health problems that often occur in elderly is a decline in cognitive function. The brain needs oxygen and glucose reserves to work, if there is a blood vessel blockage, it can cause oxygen and glucose inadequacy which can reduce the work function of brain nerve cells. Hypertension is a medical condition of an elevated vascular blood pressure above normal limits. The purpose of this study was to analyze the relationship between blood pressure and cognitive function in the elderly at RSUD Ulin Banjarmasin. This study is an analytic observational study using a cross-sectional method with total of 32 elderly people were selected using a purposive sampling method. Data was analyzed by using Pearson. The average value systolic blood pressure was 152,2 ± 5,1 from secondary data of medical record, and the average value of cognitive function using the Mini Mental State Examination (MMSE) was 26,3 ± 1,0 with Pearson correlation test results obtained value of p = 0.594 and r = 0.098. These findings provide additional evidence that there is no relation between blood systolic pressure and cognitive function in the elderly in RSUD Ulin Banjarmasin
EFEKTIVITAS EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum Ruiz & Pav.) SEBAGAI REPELEN TERHADAP NYAMUK Aedes aegypti
Authors: Putri Mayang Rustia Anggraini , Wydiamala Erida , Hayatie Lisda
Published: March 2023

Dengue Hemorrhagic Fever (DHF) is a disease caused by the dengue virus and transmitted through the bite of the Aedes aegypti mosquito. One effective option to prevent the transmission of the disease is by avoiding the bite of the Aedes aegypti mosquito by using a repellent-type insecticide. The use of chemical insecticides widely circulated in the market often has negative effects, such as irritation to the skin. Red betel leaf contains several active compounds that may act as contact poisons and are effective as repellents. The purpose of this study was to test the effectiveness of ethanol extract of red betel leaf against Aedes aegypti mosquitoes. This study was an true experimental post-test only with a control group design, consisting of 4 concentrations of ethanolic extract of red betel leaf (12.5%, 25%, 50%, 100%), DEET 15% K(+), and aquades K(-) with four replications. Serial concentrations ethanol extract of red betel leaf K(+), and K(-) were applied to the back skin of mice exposed to mosquitoes for 5 minutes for every minute. The concentration of 100% at every minute had no significant difference with the positive control (p>0.05). The conclusions from this research were red betel leaf ethanol extract with concentrations of 12.5%, 25%, 50%, and 100% was effective as a mosquito repellent Aedes aegypti, and red betel leaf ethanol extract with a concentration of 100% was equivalent to 15% DEET
HUBUNGAN TINGKAT PENDIDIKAN DAN PEKERJAAN DENGAN PENGETAHUAN TENTANG PENCEGAHAN COVID-19 DI KECAMATAN BANJARMASIN UTARA TAHUN 2021
Authors: Tezar Muhammad Ihrammuf , Heriyani Farida , Hayatie Lisda , Noor Meitria Syahadatina , Edyson Edyson
Published: March 2023

One of the big reason of the rise in COVID-19 instances is public noncompliance with health protocol implementation. What needs to be enhanced is public awareness about COVID-19 transmission prevention. The research purposes is to analyze the association between education level and occupation in accordance to COVID-19 prevention in North Banjarmasin sub-district. The research method is analytic observational with a cross-sectional approach. Sampling used a purposive sampling method with the size of 50 people from North Banjarmasin sub-district who met two criterias, namely inclusion and exclusion. According to the data gathered in this study, 45 people (90%) had a high education, while 5 people (10%) had a low education. On the occupation, there were 20 people (40%) working and 30 people (60%) not working. The results showed 39 people (78%) had good knowledge and 11 people (22%) had bad knowledge. Fisher's test  results shows that the correlations between education level and knowledge have a p value of 0.006 (p value < 0.05) with PR = 5.142857. And another results of the Fisher’s test for the correlations between occupation and knowledge have a p value of 0.489 (p value > 0.05). The results shown a significant correlations between education level and knowledge of COVID-19 prevention, and there is no remarkable correlations in occupation with knowledge about COVID-19 prevention
KEJADIAN PASIEN GAGAL JANTUNG DENGAN PENYAKIT KOMORBID HIPERTENSI DI RSUD ULIN BANJARMASIN
Authors: Amelia Reka , Adiputro Dwi Laksono , Biworo Agung , Rudiansyah Mohammad , Illiandri Oski
Published: March 2023

Heart failure is a clinical syndrome indicated by the lack of ability of the heart to supply enough blood to the peripheral tissues to fulfill the body's metabolic demands. In some cases, heart failure is usually accompanied by other pathological conditions where the process occurs at the same time as other diseases called comorbidities. In addition to the underlying disease, this disease is also a trigger, a risk factor, and a complication that further aggravates the condition of heart failure. Comorbidities are commonly found in elderly heart failure patients, resulting from the failure of several organ functions. However, the distribution of these comorbids varies in each age group. Uncontrolled hypertension causes complications of heart failure which is also a comorbid of heart failure itself. This study aims to determine the distribution of the incidence of heart failure patients with comorbid hypertension at Ulin Hospital Banjarmasin. This study used a retrospective descriptive research design with amethod total sampling by taking medical record data of heart failure patients who underwent outpatient treatment at Ulin Hospital Banjarmasin for the time range of February 2020-July 2020. From 188 heart failure patients during the time range of February 2020-July 2020, obtained as many as 84 (44.68%) patients with heart failure accompanied by hypertension. Based on the results of echocardiography, the most classifications were diastolic heart failure in 47 patients (55.95%), systolic heart failure in 21 patients (25%), and combination systolic diastolic heart failure in 16 patients (19.05%). The highest prevalence was in men 59 (70.24%). Conclusion: In patients with heart failure accompanied by comorbid hypertension, the most common finding is left ventricular diastolic heart failure, which predominantly affects male patients
LITERATURE REVIEW: GAMBARAN PEMERIKSAAN TES WIDAL DENGANPEMERIKSAAN PERTUMBUHAN KULTUR BAK-TERI SALMONELLA TYPHI PADA PASIEN DEMAM TIFOID ANAK
Authors: Paufik Sandi , Muthmainah Noor , Rahmiati Rahmiati , Pratiwi Dewi Indah Noviana , Hayatie Lisda
Published: March 2023

Typhoid fever is a systemic contamination because of Salmonella  typhi micro organism, with unfold via the fecal-oral route. Currently, the diagnosis of typhoid fever in Indonesia remains broadly utilized by the Widal take a look at method. From a few data, the sensitivity and specificity values of the Widal take a look at aren't as accurate because the Tubex ™ take a look at. Therefore, this has a look at will investigate a literature assessment that examines the assessment of the Widal take a look at with blood culture in pediatric typhoid fever patients. The layout of this studies is a literature review. Search for posted articles on google schoolar the usage of decided on keywords, namely: evaluate of the Widal take a look at with exam of the boom of Salmonella typhi microorganism in kids with typhoid fever. Based at the assessment results, the av-erage fee of sensitivity is 69.5%, specificity is 67.9%, fantastic predictive fee is 37.9% and poor predictive fee is 86.0%. Widal's exam of the 11 calculated journals has a low common PPV fee and an excessive common NPV fee. Sensitivity and Specificity values are within side the variety of 60%. Conclusion primarily based totally on evaluations from sev-eral journals, the Widal take a look at can not be used to verify a prognosis however to rule out the opportunity of a diagnosis of different diseases
LITERATURE REVIEW: PENGARUH PEMBERIAN KINESIO TAPING TERHADAP KEMAMPUAN MOBILITAS PADA PASIEN OSTEOARTRITHIS LUTUT
Authors: Fauziah Siti Amira , Siddik Muhammad , Sanyoto Didik Dwi , Putranto Bambang Dwi , Pambudi Pagan
Published: March 2023

Osteoarthritis (OA) is a degenerative disease in the elderly and attacks the joints and causes mobility problems. Kinesio taping therapy is an alternative treatment to minimize OA. This literature review aims to describe the effect of kinesio taping on mobility ability in knee osteoarthritis patients. The design of this research is Systematic Literature Reviews (SLR) which was obtained based on searching the sources of articles in English and Indonesian in the Public Medline, Science Direct, and Google Scholar databases. The article search criteria used in the literature review are articles that use English and Indonesian and are published in 2010-2021. Search articles in the literature review using the appropriate keywords consisting of kinesio taping, mobility, and knee osteoarthritis in order to obtain eight articles in literature journals. The results of a literature review showed that the administration of kinesio taping from 8 articles showed a significant effect on the mobility ability and range of motion of patients with knee osteoarthritis so as to increase mobility (p<0.05). This significant effect is indicated by a decrease in the time required for the timed up and go test (TUG).
Clusterization of vector and matrix data arrays using the combined evolutionary method of fish schools
Authors: Bodyanskiy Yevgeniy , Shafronenko Alina , Pliss Iryna
Published: March 2023

The problem of clustering data arrays described in both vector and matrix forms and based on the optimization of data distribution density functions in these arrays is considered. For the optimization of these functions, the algorithm that is a hybrid of Fish School Search, random search, and evolutionary optimization is proposed. This algorithm does not require calculating the optimized function’s derivatives and, in the general case, is designed to find optimums of multiextremal functions of the matrix argument (images). The proposed approach reduces the number of runs of the optimization procedure, finds extrema of complex functions with many extrema, and is simple in numerical implementation.
Evidence of Corporate Zakat Issuance in Sharia Bank in Southeast Asia: Profitability and Liquidity
Authors: Kusuma Wardana Guntur
Published: March 2023

This research aims to examine the effect of ROA, NPM, GPM, BOPO, and FDR, both partially and simultaneously in scientific writing. Islamic banking in Southeast Asia is the subject of research, using the panel data regression analysis method. The type and research approach used is quantitative research with an explanatory approach. Chow test, Hausman test, Lagrange multiplier test, classic assumption test, panel data regression equation test, and hypothesis testing are panel data analysis methods in research. ROA (X1), NPM (X2), GPM (X3), BOPO (X4), and FDR (X5) are the independent variables used in this study. Zakat expenditure of Islamic banking companies is the dependent variable (Y). The results of the study concluded that the ROA and BOPO variables partially had no significant effect on the zakat expenditure of Islamic banking companies in Southeast Asia, while the NPM and GPM variables partially had a significant effect on the zakat expenditure of Islamic banking companies in Southeast Asia. Meanwhile, the ROA, NPM, GPM, and BOPO variables simultaneously have a significant effect on the zakat expenditure of Islamic banking companies in Southeast Asia.
oral health status of pregnant women and awareness about oral health among pregnant patients and gynaecologists.
Authors: sadaf ayesha , khawaja hamna , mehmood ammar
Published: March 2023

Background:
Oral Health is an important part of Prenatal care. Poor oral health during pregnancy can lead to poor oral health outcomes for the mother and baby. So the aim of this study is to evaluate the oral health status of pregnant women and to determine the awareness about oral health among pregnant patients and gynaecologist, attending a government hospital gynaecology ward in Lahore Pakistan.
Methods:
It was a cross-sectional study. The study sample consisted of 220 healthy women of age 18-31 years. Study sample was divided into 2 groups. Group 1 comprised of 110 healthy pregnant women . 110 Healthy women who were not pregnant were used as the control group. The clinical examination was done based on WHO criteria for periodontal assessment and PH of the saliva was also measured. Pregnant women were interviewed according to a questionnaire and documented in a specially designed Proforma. Another questionnaire was given to 60 clinicians working in the gynecological ward and responses were recorded in a separate Proforma.
Results:
The clinical manifestations showed statistical significant values for oral health problems as compared to non-pregnant women. There were only 14.5% of pregnant women who consulted a dentist for their oral health problems during pregnancy and only 35% of the clinicians have advised their patients regarding maintenance of good oral hygiene and routine dental checkups during pregnancy.
Conclusion:
This study showed lack of awareness in pregnant women. It also showed the presence of misconceptions among gynecologists regarding dental treatment.
Psychosocial Model of Burnout among Humanitarian Aid Workers in Bangladesh: Role of Workplace Stressors and Emotion Coping
Authors: Foo Cheryl Yunn Shee , Tay Alvin Kuowei , Yang Yexinyu , Verdeli Helen
Published: March 2023

Background: While trauma exposure is an established predictor of poor mental health among humanitarian aid workers (HAWs), less is known about the role of psychosocial work-related factors. This study aims to establish a psychosocial model for burnout and psychological distress in HAWs that tests and compares the effects of adversity exposure and workplace stressors in combination, and explores the potential mediating role of individual coping styles.
Methods: Path analysis and model comparison using cross-sectional online survey data collected from full-time international and local HAWs in Bangladesh between December 2020 and February 2021. HAWs self-reported on exposure to adversities, workplace psychosocial stressors (Copenhagen Psychosocial Questionnaire), coping styles (The Coping Inventory for Stressful Situations), burnout (Maslach Burnout Inventory – Human Services Survey), and psychological distress (Kessler-6).
Results: Among N=111 HAWs, 30.6%, 16.4%, 12.7%, and 8.2% screened positive for moderate psychological distress (8 ≤ Kessler-6 ≤ 12), emotional exhaustion (EE ≥ 27), depersonalization (DP ≥ 13), and severe psychological distress (K-6 ≥ 13), respectively. 28.8% reported a history of mental disorder. The preferred model showed distinct pathways from adversity exposure and workplace stressors to burnout, with negative emotion-focused coping and psychological distress as significant intervening variables. While greater exposure to both types of stressors were associated with higher levels of burnout and distress, workplace stressors had a stronger association with psychological outcomes than adversity exposure did (β = .52, p = < .001 vs. β = .20, p = .032). Workplace stressors, but not adversities, directly influenced psychological distress (β = .45, p = < .001 vs. β = -.01, p = .927). Demographic variables, task-focused and avoidance-focused coping were not significantly associated with psychological outcomes.
Conclusions: Compared to exposure to adversities, workplace stressors primarily influence occupational stress syndromes. Reducing workplace stressors and enhancing adaptive coping can improve psychological outcomes in humanitarian staff.
Genes and pathways associated with drought tolerance in Populus wutunensis under drought stress
Authors: Zou Jixiang , Sun Jingliang , Liu Huan , Li Baisheng , Zhu Tong , Jin Chunyi , Li Xinlin , Jin Hua
Published: March 2023

Background: Populus wutunensis is widely cultivated as part of the Three-North Shelter Forest Program in China. This hybrid grows rapidly and is tolerant to salinity and drought; however, the molecular mechanisms behind the drought resistance of P. wutunensis remain unclear. We performed deep transcriptome sequencing to analyze and compare the differentially expressed genes (DEGs) between drought stress and rehydrationconditions.
Results: RNA-sequence analysis identified 5102 DEGs among the control, drought, and rehydration treatments. Further analysis of these DEGs showed that drought response genes are mainly involved in plant hormone signal transduction and galactose metabolism. Rehydration recovery mainly involves plant hormone signal transduction, flavonoid metabolism, photosynthesis-antenna proteins, and ribosome. Transcription factors play an important role in drought and rehydration by participating in signal transduction. In addition, compared with drought and control, photosynthesis-antenna proteins and ribosomewere clearly up-regulated after rewatering, which may have led to the compensatory growth of P. wutunensis during recovery.
Conclusions: Our results show that P. wutunensis responds to drought and rehydration through different pathways, and identify candidate genes related to drought and rehydration in those pathways. Our results improve the understanding of the molecular mechanisms of drought tolerance in P. wutunensis and provide a foundation for further research.
The effect of vegetarian diet on chronic kidney disease (CKD) progression – systematic review
Authors: Świątek Łukasz , Jeske Jan , Miedziaszczyk Miłosz , Idasiak-Piechocka Ilona
Published: March 2023

Background
Vegetarian diet is more and more popular around the world as the alternative to the casual diet. It is considered not only as a healthy way of consuming but also a sustainable way of living. The Chronic Kidney Disease (CKD) is a rising problem for the global population It is a main cause of death for 1.5% of global population and it is projected to increase in the future. One of the nutritional strategies to tackle the problem of CKD is a protein-restricted diet (< 0.8 grams of protein per day) It helps to decrease the proteinuria, uremic toxins, oxidative stress and improves renal function.
Method
This systematic review is meant to examine the potential benefits of changing the diet to vegetarian to delay the progression of CKD. Cochrane and Pubmed engines were used to search for the results. The investigation was carried out with the help of PRISMA 2020 Checklist and PRISMA 2020 flow diagram. Two investigators were involved into selection.
Results
According to recent studies vegetarian diet improves eGFR and reduces proteinuria. It also decreases the serum urea and acidosis. Compared to the omnivore group, vegetarians have 16% and vegans have 13% less chance of CKD development. For diabetic patients’ odds for CKD occurrence are 0.68 for both vegetarian and vegan diets indicating their protective aspect.
Conclusions
The vegetarian diet could be an alternative for low protein conventional diet not only improving the renal results but also the overall health of the patients
Set-valued Rough Set in Multi-Attribute Decision Making with Interactive Attributes
Authors: Mohanty B.K. , Aggarwal Eshika
Published: March 2023

The proposed work introduces a new methodology for solving Multiple Attribute Decision Making (MADM) problems in which the alternatives are assessed as hesitant fuzzy linguistic value (HFLV) over the attributes. The proposed MADM problem is exhibited as a rough set model with set-valued data as HFLVs. A similarity measure is defined in the set-valued information system that aids to remove the irrelevant or redundant attributes. The uncertainty due to hesitancy in HFLVs and the linked anxiety of the decision-maker therein are derived in our work after introducing the concept of the tranquility (or anxiety) in HFLTS. The proposed work introduces a new aggregation operator, Indexed Choquet Integral (ICI) that (a) aggregates the interactive attributes, (b) incorporates the decision-maker’s level of tranquility in the aggregation process, and c) estimates the weights and capacity weights of the attributes after assimilating the level of tranquilities appropriately. A comparative analysis of our paper with similar works is made and the advantages in our work are shown. The procedure introduced in the proposed work is demonstrated through a numerical example.
Brain Network Homeostasis and Plasticity of Salidroside for Achieving Neuroprotection and Treating Psychiatric Sequelae Stemming from Stress
Authors: Zhu Ting , Liu Hui , Gao Shiman , Chen Shuai , Jiang Ning , Xie Weijie
Published: March 2023

The coronavirus disease 2019 (COVID-19) pandemic has affected the mental health of individuals worldwide, and the risk of psychiatric sequelae and consequent mental disorders has increased among the general population, health care workers and patients with COVID-19. Achieving effective and widespread prevention of pandemic-related psychiatric sequelae to protect the mental health of the global population is a serious challenge. Salidroside, as a natural agent, has substantial pharmacological activity and health effects, exerts obvious neuroprotective effects, and may be effective in preventing and treating psychiatric sequelae and mental disorders resulting from stress stemming from the COVID-19 pandemic. Herein, we systematically summarise, analyse and discuss the therapeutic effects of salidroside in the prevention and treatment of psychiatric sequelae as well as its roles in preventing the progression of mental disorders, and fully clarify the potential of salidroside as a widely applicable agent for preventing mental disorders caused by stress; the mechanisms underlying the potential protective effects of salidroside are involved in the regulation of the oxidative stress, neuroinflammation, neural regeneration and cell apoptosis in the brain, the network homeostasis of neurotransmission, HPA axis and cholinergic system, and the improvement of synaptic plasticity. Notably, this review innovatively proposes that salidroside is a potential agent for treating stress-induced health issues during the COVID-19 pandemic and provides scientific evidence and a theoretical basis for the use of natural products to combat the current mental health crisis.
Detection of Neuronal Defensive Discharges Information Transmission and Characteristics in the Periaqueductal Gray Double-Subregions Using PtNPs/PEDOT:PSS-modified Microelectrode Arrays
Authors: Cai Xinxia , Lu Botao , Fan Penghui , Li Ming , Wang Yiding , Liang Wei , Yang Gucheng , Mo Fan , Xu Zhaojie , Shan Jin , Song Yilin , Liu Juntao , Wu Yirong
Published: March 2023

Appropriate defensive behaviors were selected and rapidly executed to survive in threatened animals. It was accepted the midbrain periaqueductal grey (PAG) presents an essential part of the circuitry that organize defensive behavioral responses. However, the role and correlation of different PAG subregions in the expression of different defensive behaviors remained largely unexplored. Here, we designed and manufactured a microelectrode array (MEA) to simultaneously detect the activities of dPAG and vPAG neurons in freely-behaving rats. The PtNPs/PEDOT:PSS nanocomposites were modified onto the MEAs to improve the detection performances of the MEAs. Subsequently, the predator odor was used to induce the rat's innate fear, and the changes and information transmission in neuronal activities were detected in dPAG and vPAG. Our results showed that dPAG and vPAG both participated in the innate fear, but the activation degree was distinct in different defense behavior. During the flight, neuronal responses were stronger and earlier in the dPAG compared with the vPAG, while vPAG neurons responded greater during freezing. The application of high-performance MEA detected that neural information spread from activated dPAG to weakly activated vPAG. Our research also revealed that dPAG and vPAG neurons had different defensive discharges characteristics, and dPAG neurons participated in the regulation of defense response with burst-firing patterns. The slow activation and continuous-firing of vPAG neurons were matched with the regulation of long-term freezing response. The results demonstrated the important role of PAG neuronal activities in the control of different aspects of defensive behaviors and provided novel insights for investigating defense from the electrophysiological perspective.
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
Authors: Pachnis Vassilis , Laddach Anna , Chng Song Hui , Lasrado Reena , Progatzky Franze , Shapiro Michael , Erickson Alek , Sampedro-Castaneda Marisol , Artemov Artem , Bon-Frauches Ana Carina , Kleinjung Jens , Boeing Stefan , Ultanir Sila , Adameyko Igor , Amaniti Eleni-Maria
Published: March 2023

Development of the nervous system is underpinned by changes in gene expression and chromatin configuration during embryogenesis and early postnatal life. To uncover the molecular mechanisms orchestrating cell lineage differentiation and maturation in the enteric nervous system (ENS), we profiled the transcriptome and chromatin accessibility of autonomic neural crest cells (ANCCs) and their progeny in the mouse gut at key developmental stages and adulthood. Integrative analyses defined a differentiation trajectory delineated by ENS progenitors transitioning during development to an enteric glial cell (EGC) state and sequential neurogenic branches driven by shared transcriptional programs. Key loci implicated in neuronal differentiation of early ENS progenitors maintain an open chromatin profile in mature EGCs, enabling these cells to maintain neurogenic potential and return, under appropriate conditions, to developmentally upstream positions of the gliogenic axis. Molecular profiling of lineally marked enteric glial cells (EGCs) in a gut injury model and a novel cell culture system of enteric neurogenesis, demonstrated that neuronal differentiation of mature EGCs is driven by transcriptional programs employed in vivo by early ENS progenitors. Our work advances our understanding of the dynamic regulatory landscape underpinning mammalian ENS development and provides a basis for exploring glial cells as therapeutic agents for the treatment of neural deficits.
Effects of 940 nm low-level laser therapy for the treatment of primary dysmenorrhea: a double-blind, randomized, placebo-controlled trial
Authors: Wang Ran , Fan Xiaoxue , Shao Mengmeng , Zhang Yunqian , He Jian , Yin Jiang , Lu Lijuan
Published: March 2023

Background: Primary dysmenorrhea (PD) is one of the most common and disturbing gynecological disorders, and effective nonpharmacological treatments are still in urgent demand. low-level laser therapy (LLLT) showed wide application prospects in pain management. This study aimed to assess the therapeutic effects and safety of 940nm LLLT for PD.
Methods: 100 participants with PD were allocated at random (2:1) to the LLLT group (n=68) or the control group (n=32) and treated with 940nm LLLT at the Guan Yuan acupoint or placebo for 30 minutes once daily before menstruation onset. Participants were treated for three menstrual cycles (T1, T2, T3) and followed up for another three cycles (T4, T5, T6). Visual analogue scale (VAS), Abdominal pain time (APT), Abdominal pain degree (APD), COX menstrual symptom scale (CMSS), Self-rating anxiety Scale (SAS), Self-rating depression scale (SDS), rescue medicine usage and complications at each menstrual cycle were recorded and compared. Change of VAS, APT, APD, CMSS, SAS and SDS from baseline at T3 was compared with those at T1 and T2.
Results: Compared with baseline, VAS, APT, APD, CMSS, SAS and SDS were significantly decreased at all menstrual cycles in the LLLT group (except APT and SAS at T5-6). Compared with the control group, VAS at T1-5, APT and SDS at T2-4, APD and CMSS at T1-6, and SAS at T1-4 were found significantly lower in the LLLT group. Compared with T1 or T2, greater improvement from baseline was found in all parameters in the LLLT group at T3 (except APD and SAS with T2). The rate of rescue medication use in the LLLT group was significantly lower than that in the control group at T3 and T6. No adverse reaction was found.
Conclusion: 940nm LLLT is a safe and promise complementary method for PD treatment with a cumulative feature of therapeutic effect.
Trial registration: ChiCTR2100046199, 09/05/2021.
Visualization of green building landscape space environment design based on image processing and artificial intelligence algorithm
Authors: ZHOU Jianbo
Published: March 2023

The development direction of future architectural design should be in line with environmental protection, green and energy conservation, so as to meet people's sustainable development needs. The promotion of green building technology needs to involve multi-level and multi-disciplinary knowledge and social factors. Through a large number of green building projects, we can know that its ecological landscape not only has artistic value, but also can reflect obvious ecological value. An important concept in the concept of sustainable development is the green building landscape. Based on this background, this paper introduces artificial intelligence algorithm and designs a visual system around the concept of landscape space environment design. This system can be operated in two different forms, in offline application, image training is mainly carried out on the server side; In the online stage, the collected images are uploaded to the server using the Android platform, and the server side performs a series of operations such as image target detection, and then uses the Android mobile terminal to display the virtual reality fusion scene. The system test shows that the green building environment visualization system can not only make full use of the idle time of the cable drainage reader, but also will not affect the search operation in the next stage. The average delay is reduced by 16%, which proves the practicability of the software. In this paper, artificial intelligence algorithm is introduced into the field of green landscape space environment design, and an effective visualization system is constructed.
Impact of an immersive, interactive medical education initiative on guideline-based retinal disease management knowledge/competence and effectual practice change
Authors: Singh Rishi P. , Welch Lauren , Longo Nicole , Frese Matt
Published: March 2023

Background: Retinal diseases, including wet or dry age-related macular degeneration, diabetic macular edema, and diabetic retinopathy (DR), are underdiagnosed and undertreated in the United States. Clinical trials support the effectiveness of anti-vascular endothelial growth factor (anti-VEGF) therapies for several retinal conditions, but real-world data suggest underuse by clinicians, resulting in patients experiencing poorer visual outcomes over time. Continuing education (CE) has demonstrated effectiveness at changing practice behaviors, but more research is needed to understand whether CE initiatives can help address diagnostic and treatment gaps for patients with retinal diseases in the long-term.
Methods: This case-control study analyzed pre-/post-test knowledge of retinal diseases and guideline-based screening and intervention among 10,786 healthcare practitioners who participated in the modular, interactive CE initiative VISION RELIEF. An additional medical claims analysis by IQVIA provided data on practice change, evaluating use of VEG-A inhibitors among retina specialist and ophthalmologist learners (n=7,827) pre-/post-education, compared to a matched control group of non-learners. Outcomes were pre-/post-test change in knowledge/competence and clinical change in application of anti-VEGF therapy, as identified by the medical claims analysis.
Results: Learners from all disciplines significantly improved knowledge/competence scores on items relating to early identification and treatment, identifying patients who could benefit from anti-VEGF agents, using guideline-recommended care, recognizing the importance of screening and referral, and recognizing the importance of early detection and care for DR (all P-values=0.003 to 0.004). Compared with matched controls, learners’ incremental total injections for anti-VEGF agents utilized for retinal conditions increased more after the CE intervention (P<0.001); specifically, there were 18,513 more (new) anti-VEGF injections prescribed than from non-learners (P<0.001).
Conclusions: This modular, interactive, immersive CE initiative resulted in significant knowledge/competence gains among a nationwide sample of retinal disease care providers and changes in practice-related treatment behaviors (i.e., appropriate consideration and greater incorporation of guideline-recommended anti-VEGF therapies) among participating ophthalmologists and retina specialists compared to a carefully matched control. Future studies will utilize medical claims data to show longitudinal impact of this CE initiative on treatment behavior among specialists as well as its impact on diagnosis and referral rates among optometrists and primary care providers who participate in future programming.
A matching-synergy degree-based optimization selection method for cloud manufacturing service composition
Authors: Yin Chao , Li Shanglin , Li Xiaobin
Published: March 2023

In a cloud manufacturing scenario, the matching degree between manufacturing tasks and cloud services, as well as the synergy degree between multiple selected cloud services are key metrics to measure the benefits of cloud manufacturing service application. However, the latter is often overlooked in the cloud service selection process. In this paper, a matching-synergy analysis-based optimization method of cloud manufacturing service composition is proposed. Firstly, an evaluation system of cloud service composition quality is established, including service matching degree (SM), service composition synergy (CS), and other metrics, such as service time (T), service cost (C) and reliability (R). Secondly, considering the interests of both service requestors and service resource providers, a two-constraint combination preference model is constructed, and solved by using the improved ant colony algorithm (IACO). Finally, the feasibility and effectiveness of the proposed method are verified with the example of an automobile bumper cloud service.