bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the Effects of Some Cardiovascular Drugs on Angiogenesis by Transgenic Zebrafish
Authors: Lv Hui , Liu Bo , Qin Yongwen
Published: April 2023

Introduction. Angiogenesis contributes to the pathophysiology of cardiovascular disease (CVD). Some cardiovascular drugs used in the treatment of CVD have an effect on the process of angiogenesis. Methods. Transgenic Tg (flk1: EGFP) zebrafish embryos were used to identify the effects of some cardiovascular drugs on angiogenesis during vertebral development in vivo. Zebrafish embryos at a one-cell stage or two-cell stage were cultured with embryo medium containing cardiovascular drugs at a final solvent concentration of 0.5% (

V
/
V

) dimethyl sulfoxide (DMSO) for 24 hours in 24-well plates. Results. We found that 6 drugs including isosorbide mononitrate, amlodipine, bisoprolol fumarate, carvedilol, irbesartan, and rosuvastatin calcium may affect angiogenesis by vascular endothelial growth factor (VEGF) signaling pathway. Conclusion. These new findings of some cardiovascular drugs should improve the treatment of cardiovascular diseases.
Insights into the Effect of Micropore Structure and Mineralogy on Adsorbed Tight Oil in the Huaqing Area, Ordos Basin, China
Authors: Zhou Qianshan , Zhang Dongwei , Xi Mingli , Zhao Yilin , Li Chao , Chen Guojun , Lyu Chengfu , Ma Xiaofeng
Published: April 2023

There is great potential for tight oil as an alternative to conventional fossil fuels throughout the world. Adsorption, mineralogy, and pore structure of tight sandstone are very important factors for the efficient development of adsorbed tight oil from tight sandstone oil reservoirs. In this study, the occurrence morphology of tight oil adsorbed to varying pore structures was examined, as well as the relationship between adsorption content and occurrence morphology. X-ray energy dispersive spectra, environmental scanning electron microscope observations, and thin fluorescence sections were used to describe the occurrence morphology of adsorbed tight oil in tight sandstone reservoirs. It was found that adsorbed tight oil can be classified into five types: emulsion, cluster, throat, thin-film, and isolation, with average contents of 34.9%, 14.5%, 3.1%, 42.7%, and 4.7%, respectively. In addition, a Soxhlet extraction was developed with four pore structures to describe the geological effects of adsorbed tight oil in reservoirs. The adsorption content of tight oil ranges from 4.015 mg/g to 16.987 mg/g, with an average of 10.115 mg/g. The order of adsorption content for different occurrence morphologies is as follows: emulsion form > throat form > cluster form > isolation form > thin-film form. It is the size and connectivity of the porous throat that determines the desorption efficiency of tight oil. An important outcome of this study can be the introduction of rational development plans and the improvement of oil recovery efficiency for tight oil reservoirs.
Salivary Antioxidant Profile in Patients with Systemic Sclerosis and Periodontitis
Authors: Sredojevic Stefan I. , Dolijanovic Slavica Pavlov , Dozic Ivan , Pficer Jovana Kuzmanovic , Aleksic Zoran , Nikolic-Jakoba Natasa S.
Published: April 2023

Objective. The aim of the present study was to compare periodontal status and antioxidant profile in unstimulated saliva of systemic sclerosis (SSc) patients with periodontitis and systemically healthy periodontitis patients. Design. Twenty patients with established diagnoses of systemic sclerosis and periodontitis (SSc group) and 20 systemically healthy individuals with periodontitis (P group) were enrolled in the study. Clinical periodontal parameters (clinical attachment level (CAL), gingival recession (GR), periodontal probing depth (PPD), and gingival index (GI)) and concentration of uric acid (UA), superoxide dismutase (SOD), and glutathione peroxidase (GPX) in unstimulated saliva samples were assessed. Results. There were significantly higher mean values of CAL (

4.8
±
0.21
 
mm

versus

3.18
±
0.17
 
mm

;

p
≤
0.001

) and GR (

1.66
±
0.90
 
mm

versus

0.46
±
0.54
 
mm

;

p
≤
0.001

) in the SSc group when compared to the P group. Significantly higher level of GPX (

p
≤
0.001

) and SOD (

p
≤
0.001

) in unstimulated saliva was detected in the SSc group in comparison with the P group. The specific activity of UA did not significantly differ between the two groups (

p
=
0.083

). Conclusion. The results may indicate higher periodontal destruction and antioxidant perturbations in unstimulated saliva of SSc patients with periodontitis compared to systemically healthy periodontitis patients.
The Effect of Glycerol Monolaurate on Intestinal Health and Disease Resistance in Cage-Farmed Juvenile Pompano Trachinotus ovatus
Authors: Lin Huaxing , Tan Beiping , Yang Qihui
Published: April 2023

This research studied the effects of glycerol monolaurate (GML) to diets on the digestive capacity, intestinal structure, intestinal microbiota, and disease resistance for juvenile pompano Trachinotus ovatus (meanweight=14.00±0.70 g). T. ovatus were, respectively, fed six diets containing 0.00, 0.05, 0.10, 0.15, 0.20, and 0.25% GML for 56 days. The highest weight gain rate was observed in the 0.15% GML group. In the intestine, amylase activities in the 0.10, 0.15, 0.20, and 0.25% GML groups were significantly increased, compared with 0.00% GML group (P<0.05). Lipase activities in the 0.10 and 0.15% GML groups were significantly increased (P<0.05). Similar significant elevations in the protease activities were also found in the 0.10, 0.15, and 0.20% GML groups (P<0.05). Amylase activities were significantly higher in the 0.10, 0.15, 0.20, and 0.25% GML groups than that in the 0.00% GML group (P<0.05). Villus lengths (VL) and muscle thicknesses (MT) of the 0.05, 0.10, 0.15, and 0.20% GML groups were significantly enhanced, and the villus widths (VW) in the 0.05, 0.10, and 0.15% groups were significantly increased (P<0.05). Additionally, 0.15% GML significantly improved the intestinal immunity by upregulating interleukin 10 (il-10), increasing beneficial bacteria abundances (e.g., Vibrio, Pseudomonas, and Cetobacterium), downregulating nuclear factor kappa b (nf-κb) and interleukin 8 (il-8), and decreasing harmful bacteria abundances (e.g., Brevinema and Acinetobacter) (P<0.05). After challenge test, GML significantly increased the survival rate (80%–96%) (P<0.05). In addition, ACP and AKP activities in the GML-supplemented groups were significantly higher than those in the 0.00% GML group, and LZM activity was significantly higher in the 0.05, 0.10, 0.15, and 0.20% GML groups than that in the 0.00% GML group (P<0.05). In summary, 0.15% GML significantly promoted the intestinal digestibility, improved the intestinal microflora, regulated intestinal immune-related genes, and increased resistance to V. parahaemolyticus of juvenile pompano T. ovatus.
Hydromagnetic Flow of Two Immiscible Couple Stress Fluids in an Inclined Porous Channel: Effects of Slip Boundary
Authors: Bitla Punnamchandar , Sitotaw Fekadu Yemataw
Published: April 2023

In this study, we investigated the effects of slip boundary and magnetic field on the flow of two immiscible couple stress fluids in an inclined porous media channel. The Stokes model was used to define the two couple stress fluids. The fluids in both the regions are assumed to be incompressible and immiscible and the transport properties in the two regions are assumed to be constant. The governing coupled linear ordinary differential equations are made dimensionless by using appropriate fundamental quantities. The expressions for the velocity components in both the regions are obtained in closed form using the undetermined coefficient method; by applying slip boundary condition at the boundary of the channel and at fluid‐fluid interface, the continuity of velocities, vorticities, shear stresses, and couple stresses are applied. The effects of the nondimensional parameters including the couple stress parameters, slip parameter, Hartmann number, Darcy number, and the ratio of basic fluid properties on the velocity components are presented graphically; the flow rate and shear stress are presented in table and discussed briefly. It is reported that the presence of couple stresses and magnetic field have a declining impact while slip boundary has an enhancement impact on the fluid velocity and the volumetric flow rate. In the absence of couple stress, the results for the liming case as s⟶∞(η⟶0) for Newtonian flow are achieved and further limiting cases are established and briefly addressed.
Experimental Study on the Distribution of Retained Fracturing Fluids and Its Effect on the Permeability and Wettability in Tight Oil Reservoirs
Authors: Gu Tuan , Tuo Zhilin , Fan Tao , Shi Dongpo , Mu Chun , Xu Shucan , Zhou Desheng
Published: April 2023

It is not clear how the distribution of retained fracturing fluids and its effect on the permeability and wettability in tight oil reservoirs interact. Especially, there are more qualitative studies and less quantitative studies on this issue. Under laboratory experimental conditions, this paper clarifies the distribution of retained fracturing fluids in the core and reveals the influence rule of retained fracturing fluids on tight reservoir permeability and wettability. It is found that the main retention space of retained fracturing fluids in a tight reservoir is a microporous interval, and the residual oil after oil displacement by retained fracturing fluids mainly exists in the core in the form of dots or porphyries. The smaller permeability and porosity of the core will lead to more retained fracturing fluids. The permeability of different cores after fracturing fluid retention has decreased to varying degrees compared with that before fracturing fluid retention. The wettability of core slices before and after fracturing fluid retention was tested, and the effect of retained fracturing fluids on reservoir wettability was not significant. This study has important significance for improving the recovery of tight oil reservoirs and enhancing the understanding of postfracturing fluid retention.
Supplementary Figure S8 from Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations
Authors: Ohshima Keiichi , Nagashima Takeshi , Fujiya Keiichi , Hatakeyama Keiichi , Watanabe Yuko , Morimoto Kimiko , Kamada Fukumi , Shimoda Yuji , Ohnami Sumiko , Naruoka Akane , Serizawa Masakuni , Ohnami Shumpei , Kenmotsu Hirotsugu , Shiomi Akio , Tsubosa Yasuhiro , Bando Etsuro , Sugiura Teiichi , Sugino Takashi , Terashima Masanori , Uesaka Katsuhiko , Urakami Kenichi , Akiyama Yasuto , Yamaguchi Ken
Published: April 2023

Functional enrichment analysis of the differentially expressed genes in malignant GISTs with KIT Δ557–558.
Supplementary Figure S7 from Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations
Authors: Ohshima Keiichi , Nagashima Takeshi , Fujiya Keiichi , Hatakeyama Keiichi , Watanabe Yuko , Morimoto Kimiko , Kamada Fukumi , Shimoda Yuji , Ohnami Sumiko , Naruoka Akane , Serizawa Masakuni , Ohnami Shumpei , Kenmotsu Hirotsugu , Shiomi Akio , Tsubosa Yasuhiro , Bando Etsuro , Sugiura Teiichi , Sugino Takashi , Terashima Masanori , Uesaka Katsuhiko , Urakami Kenichi , Akiyama Yasuto , Yamaguchi Ken
Published: April 2023

DNA methylation in each autosome of GISTs. Genome-wide DNA methylation sites are shown in 300-kb bins.
Supplementary Figure S2 from Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations
Authors: Ohshima Keiichi , Nagashima Takeshi , Fujiya Keiichi , Hatakeyama Keiichi , Watanabe Yuko , Morimoto Kimiko , Kamada Fukumi , Shimoda Yuji , Ohnami Sumiko , Naruoka Akane , Serizawa Masakuni , Ohnami Shumpei , Kenmotsu Hirotsugu , Shiomi Akio , Tsubosa Yasuhiro , Bando Etsuro , Sugiura Teiichi , Sugino Takashi , Terashima Masanori , Uesaka Katsuhiko , Urakami Kenichi , Akiyama Yasuto , Yamaguchi Ken
Published: April 2023

KIT exon 11 mutations detected in 30 GIST samples.
Supplementary Figure S1 from Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations
Authors: Ohshima Keiichi , Nagashima Takeshi , Fujiya Keiichi , Hatakeyama Keiichi , Watanabe Yuko , Morimoto Kimiko , Kamada Fukumi , Shimoda Yuji , Ohnami Sumiko , Naruoka Akane , Serizawa Masakuni , Ohnami Shumpei , Kenmotsu Hirotsugu , Shiomi Akio , Tsubosa Yasuhiro , Bando Etsuro , Sugiura Teiichi , Sugino Takashi , Terashima Masanori , Uesaka Katsuhiko , Urakami Kenichi , Akiyama Yasuto , Yamaguchi Ken
Published: April 2023

Circos plots of the 30 GIST genomes in our study cohort.
Supplementary Data S4 from Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations
Authors: Ohshima Keiichi , Nagashima Takeshi , Fujiya Keiichi , Hatakeyama Keiichi , Watanabe Yuko , Morimoto Kimiko , Kamada Fukumi , Shimoda Yuji , Ohnami Sumiko , Naruoka Akane , Serizawa Masakuni , Ohnami Shumpei , Kenmotsu Hirotsugu , Shiomi Akio , Tsubosa Yasuhiro , Bando Etsuro , Sugiura Teiichi , Sugino Takashi , Terashima Masanori , Uesaka Katsuhiko , Urakami Kenichi , Akiyama Yasuto , Yamaguchi Ken
Published: April 2023

Data for gene expression signatures.
Supplementary Data S2 from Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations
Authors: Ohshima Keiichi , Nagashima Takeshi , Fujiya Keiichi , Hatakeyama Keiichi , Watanabe Yuko , Morimoto Kimiko , Kamada Fukumi , Shimoda Yuji , Ohnami Sumiko , Naruoka Akane , Serizawa Masakuni , Ohnami Shumpei , Kenmotsu Hirotsugu , Shiomi Akio , Tsubosa Yasuhiro , Bando Etsuro , Sugiura Teiichi , Sugino Takashi , Terashima Masanori , Uesaka Katsuhiko , Urakami Kenichi , Akiyama Yasuto , Yamaguchi Ken
Published: April 2023

SNVs/Indels identified in the 30 GIST cases in our study cohort.
Combined Hepatocellular-Cholangiocarcinoma: Biology, Diagnosis, and Management
Authors: Ye Liangtao , Schneider Julia S. , Ben Khaled Najib , Schirmacher Peter , Seifert Carolin , Frey Lea , He Yulong , Geier Andreas , De Toni Enrico N. , Zhang Changhua , Reiter Florian P.
Published: April 2023

Background: Combined hepatocellular-cholangiocarcinoma (cHCC-iCCA) is a rare type of primary liver cancer displaying characteristics of both hepatocytic and cholangiocytic differentiation. Summary: Because of its aggressive nature, patients with cHCC-iCCA exhibit a poorer prognosis than those with HCC. Surgical resection and liver transplantation may be considered curative treatment approaches; however, only a minority of patients are eligible at the time of diagnosis, and postoperative recurrence rates are high. For cases that are not eligible for surgery, locoregional and systemic therapy are often administered based on treatment protocols applied for HCC or iCCA. Owing to the rarity of this cancer, there are still no established standard treatment protocols; therefore, the choice of therapy is often personalized and guided by the suspected predominant component. Further, the genomic and molecular heterogeneity of cHCC-iCCA can severely compromise the efficacy of the available therapies. Key Messages: In the present review, we summarize the latest advances in cHCC-iCCA and attempt to clarify its terminology and molecular biology. We provide an overview of the etiology of cHCC-iCCA and present new insights into the molecular pathology of this disease that could contribute to further studies aiming to improve the patient outcomes through new systemic therapies.
Perioperative Maternal-Fetal Outcomes in the Setting of Minimally Invasive Fetal Therapy for Complex Monochorionic Pregnancies with Monitored Anesthesia Care
Authors: Nelson Olivia , Khalek Nahla , Wu Lezhou , William Meryl S. , Wohler Brittany , Lin Elaina E. , Tran Kha M. , Simpao Allan F.
Published: April 2023

Introduction: Fetoscopic selective laser photocoagulation (FSLPC) and selective cord occlusion with radiofrequency ablation (RFA) can improve fetal outcomes when vascular anastomoses between fetuses cause twin-to-twin transfusion syndrome (TTTS) or selective fetal growth restriction (sFGR) in multiple gestation pregnancies with monochorionic placentation. This study analyzed perioperative maternal-fetal complications and anesthetic management in a high-volume fetal therapy center over a 4-year period. Methods: Included patients received MAC for minimally invasive fetal procedures for complex multiple gestation pregnancies between January 1, 2015, and September 20, 2019. Maternal and fetal complications, intraoperative maternal hemodynamics, medication usage, and reasons for conversion to general anesthesia, if applicable, were analyzed. Results: A total of 203 (59%) patients underwent FSLPC and 141 (41%) had RFA. Four patients (2%; rate 95% CI: 0.00039, 0.03901) undergoing FSLPC had conversion to general anesthesia. No conversions to general anesthesia occurred in the RFA group. The incidence of maternal complications was higher in those who underwent FSLPC. No aspiration or postoperative pneumonia events were observed. Medication usage was similar in FSLPC and RFA groups. Conclusion: A low rate of conversion to general anesthesia and no serious adverse maternal events were observed in patients receiving MAC.
Da imitação teatral, ou “Ensaio extraído dos Diálogos de Platão”
Authors: Rousseau Jean-Jacques , Yasoshima Fabio Stieltjes
Published: April 2023

Tradução de Da imitação teatral, ou “Ensaio extraído dos Diálogos de Platão”, de J-J Rousseau
Crítica – As Semanas de Arte Moderna de 2022
Authors: Ferreira José Bento Machado
Published: April 2023

Crítica - As Semanas de Arte Moderna de 2022
O acervo de Augusto Boal um exemplo do papel das mídias digitais na salvaguarda do patrimônio cultural brasileiro
Authors: Razuk Eduardo
Published: April 2023

O artigo reporta as dificuldades enfrentadas na manutenção dos acervos pessoais, tão relevantes às pesquisas que envolvem a história de vida e a obra de personalidades da cultura brasileira e valoriza a importância dos acervos digitais na solução dessas dificuldades e no apoio à pesquisa . Para tanto, será apresentado como ilustração, o acervo pessoal do grande teatrólogo brasileiro, Augusto Boal.
Deep Imaging to Dissect Microvascular Contributions to White Matter Degeneration in Rodent Models of Dementia
Authors: Stamenkovic Stefan , Li Yuandong , Waters Jack , Shih Andy
Published: April 2023

The increasing socio-economic burden of Alzheimer disease (AD) and AD-related dementias has created a pressing need to define targets for therapeutic intervention. Deficits in cerebral blood flow and neurovascular function have emerged as early contributors to disease progression. However, the cause, progression, and consequence of small vessel disease in AD/AD-related dementias remains poorly understood, making therapeutic targets difficult to pinpoint. Animal models that recapitulate features of AD/AD-related dementias may provide mechanistic insight because microvascular pathology can be studied as it develops in vivo. Recent advances in in vivo optical and ultrasound-based imaging of the rodent brain facilitate this goal by providing access to deeper brain structures, including white matter and hippocampus, which are more vulnerable to injury during cerebrovascular disease. Here, we highlight these novel imaging approaches and discuss their potential for improving our understanding of vascular contributions to AD/AD-related dementias.
Dissociable Contributions of Thalamic-Subregions to Cognitive Impairment in Small Vessel Disease
Authors: Li Hao , Cai Mengfei , Jacob Mina A. , Norris David G. , Marques José P. , Chamberland Maxime , Duering Marco , Kessels Roy P.C. , de Leeuw Frank-Erik , Tuladhar Anil M.
Published: April 2023

Background:

Structural network damage is a potentially important mechanism by which cerebral small vessel disease (SVD) can cause cognitive impairment. As a central hub of the structural network, the role of thalamus in SVD-related cognitive impairments remains unclear. We aimed to determine the associations between the structural alterations of thalamic subregions and cognitive impairments in SVD.

Methods:

In this cross-sectional study, 205 SVD participants without thalamic lacunes from the third follow-up (2020) of the prospective RUN DMC study (Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort), which was initiated in 2006, Nijmegen, were included. Cognitive functions included processing speed, executive function, and memory. Probabilistic tractography was performed from thalamus to 6 cortical regions, followed by connectivity-based thalamic segmentation to assess each thalamic subregion volume and connectivity (measured by mean diffusivity [MD] of the connecting white matter tracts) with the cortex. Least absolute shrinkage and selection operator regression analysis was conducted to identify the volumes or connectivity of the total thalamus and 6 thalamic subregions that have the strongest association with cognitive performance. Linear regression and mediation analyses were performed to test the association of least absolute shrinkage and selection operator-selected thalamic subregion volume or MD with cognitive performance, while adjusting for age and education.

Results:

We found that higher MD of the thalamic-motor tract was associated with worse processing speed (β=−0.27;
P
<0.001), higher MD of the thalamic-frontal tract was associated with worse executive function (β=−0.24;
P
=0.001), and memory (β=−0.28;
P
<0.001), respectively. The mediation analysis showed that MD of thalamocortical tracts mediated the association between corresponding thalamic subregion volumes and the cognitive performances in 3 domains.

Conclusions:

Our results suggest that the structural alterations of thalamus are linked to cognitive impairment in SVD, largely depending on the damage pattern of the white matter tracts connecting specific thalamic subregions and cortical regions.
Chronic stress and temporal self-regulation in sales managers
Authors: Shirokaya Marina Yu. , Gorbatych Matvey V.
Published: April 2023

Background. Time factor plays a signiacant role in creating unfavorable conditions for work activity. Temporal characteristics of labor oben become one of the main factors in the emergence of organizational stress (Vodopyanova, 2009; Artamonova, Leonova, 2009). ce activities of sales managers considered in the work are characterized by a signiacant severity of stress tension with time and deadline pressure leading among the numerous stressors in this professional activity. ce problem of lack of time for personal life and the lack of balance between work and life stem from temporary tension. Temporal aspects of work, being aware of them, subjective assessment and time management require separate consideration from the perspective of professional development and overcoming stress for sales managers. Objective. ce study focuses on the multi-level indicators of temporal self-regulation in chronic stress in the hard work of representatives of managerial professions. To achieve the goal, the task of conducting an empirical study aimed at identifying the features of self-organization, self-management and experiencing time at work, as well as anding the place and role of time aspects in the chronic stress development among sales managers was set. Sample. ce sample is represented by 154 sales managers (mean age 34 years, 56 men, 95 women) working in large wholesale and several small wholesale trade and industrial organizations in diderent cities of Russia. Methods. Data collection was carried out electronically using Google forms questionnaires. ce study was conducted in 2019–2020. To study the level of occupational stress, the methodology “Questionnaire for assessing the level of experiences of acute and chronic stress” was used (Leonova, Kachina, 2007). In order to study the assessment of working time and its experience, the “Time Perspective Questionnaire” (Zimbardo, Sword, Sword, 2017), “Manager’s Time Syndrome” (Vodopyanova, 2018), “Questionnaire for Self-Organization of Activities” (Mandrikova, 2010) and the questionnaire “Overall indicator of the edectiveness of the system of self-management of working time”, specially developed by our group, were used. Results. We have obtained numerous interrelations between indicators of chronic stress and temporal self-regulation. Such predictors of chronic stress as temporal orientation to the negative past, lack of expressiveness of aspirations to the future and hedonistic present were identiaed. ce presence of chronic stress and the experience of lack of time were predictors for a decrease in the edectiveness of self-management of working time (time management) among sales managers. Conclusion. ce multi-level indicators of temporal self-regulation considered, including temporal orientations, experience of lack of time, self-organization of activities and time management, can on the one hand, be predictors of chronic stress, while on the other hand, act as a resource for overcoming it in the activities of sales managers.
Labor interests as a key factor in the involvement and performance of educational technology employees
Authors: Lobanova Tatiana N.
Published: April 2023

Background. Work activity in a post-industrial digital society diYers fundamentally from our past ideas about work. Ze characteristics of this activity are changing just as rapidly, the motivation in employees of the information technology sphere, in particular. In this regard, the study of the role of labor interests, their relationship with the involvement and e[ciency of workers in this area remains an urgent problem. Objective. Ze research analyses the relationship between labor interests as a value-motivational, emotionally colored position of an employee, expressed in a practical attitude to work, and the organizational and job involvement and employee’s performance. Methods. To measure the level of employees’ involvement and their interest, an author’s questionnaire of 54 questions was compiled, including the scales of work and organizational involvement and the measurement of labor interests. Also, evaluation sheets to measure performance were developed in collaboration with the heads of the company in question. Zree groups of criteria were covered: qualitative, quantitative and temporal. Sample. Ze study involved personnel of an international company operating in the \eld of educational technologies in Russian and European markets. Ze survey involved respondents of various job levels from top management to specialists (N = 155, 48% women, 52% men), aged 18 to 36 years with work experience from 0.5 to 3 years. 60% of respondents have higher education, 40% of participants combine work and studies, reporting incomplete higher education. Results. Ze study results were veri\ed with the Spearman correlation analysis. Factors of organizational and work involvement, types of labor interests, as well as performance were subjected to veri\cation. Signi\cant correlations were found on almost all scales, which con\rmed the hypothesis that posited involvement of employees as being directly dependent on their interests. Career interests were signi\cantly associated with the qualitative criterion of performance at the level of p < 0.01. Referential interests also had a correlation with employees’ performance. It turned out that top managers of the company have the highest performance and involvement rates. Conclusion. From the obtained correlation of professional interests and work involvement, it follows that a person is more actively immersed in work when the professional interests are taken into account. Ze connection between corporate interests and organizational involvement was also con\rmed. It was found that organizational and job involvement are associated with such spheres of employees’ interest as group, career, professional, corporate and referential.
New record of the rare genus Analysson Krombein, 1985 (Hymenoptera: Crabronidae) from Vietnam, with description of a new species
Authors: PHAM PHONG HUY
Published: April 2023

Analysson Krombein 1985, a rare genus of the family Crabronidae, is recorded for the first time from Vietnam. Analysson vietnamensis Pham sp. nov., the second species of the genus, is described and illustrated. A key to both species of Analysson is presented.
On the taxonomic status of Agelanius antenninus (Philip) (Diptera: Tabanidae) from Peru based upon evidence from a morphological analysis of the holotype
Authors: GONZÁLEZ CHRISTIAN R.
Published: April 2023

The taxonomic status of Agelanius antenninus (Philip, 1969) was evaluated on the basis of a morphological study of the holotype, described from Huánuco, Peru. Results of analyses of A. antenninus and its morphological comparison with A. meridianus Rondani, the type-species of Agelanius Rondani, proved that A. antenninus does not belong to the genus Agelanius. The subgenus Styphocera Philip is reinstated as a valid subgenus of Stypommisa Enderlein. Thus, the generic combination Stypommisa (Styphocera) antennina Philip should be reinstated for this species.
Comparison of Spatiotemporal Distribution and Occurrence Conditions of Large and Small Hail Events in the Beijing–Tianjin–Hebei Region
Authors: Wang Chenxi , Zheng Dong , Zhang Yijun , Yao Wen , Zhang Wenjuan
Published: April 2023

Using hail records at national meteorological stations for 2014–18, ERA-Interim reanalysis data, and Doppler weather radar data, the spatiotemporal distribution of hail events (HEs) in the Beijing–Tianjin–Hebei region is revealed, and the environmental conditions and hailstorm structures corresponding to large hail (diameter ≥ 20 mm) events (LHEs) and small hail (2 ≤ diameter < 20 mm) events (SHEs) are compared. It is found that, although HEs may be more frequent in mountainous areas, most LHEs occur in the plains and near the foot of the mountains. The HE frequency peaks in June, and the average hailstone size is larger during May and June. According to daytime records, the HEs predominantly occur in the afternoon and evening, whereas LHE tends to be more in the evening. Comparison of environmental parameters suggests that, relative to SHEs, LHEs tend to correspond to higher 2-m temperature, a wetter lower layer, a larger difference in relative humidity between 925 and 500 hPa, greater unstable energy, and stronger wind shear. Hailstorms associated with LHEs tend to feature greater mesoscale rotation velocity than those associated with SHEs. Hailstorms usually show rapid increase (RI) in vertically integrated liquid (VIL) before hailstones are observed. A significant difference between the hailstorms associated with LHEs and SHEs is that the former has an obviously longer time interval between the end of VIL RI and the occurrence of hailfall, indicating that the large hail size benefits from the constant supply of liquid water and the hail can be lifted by updrafts for a long time.

Significance Statement

Whereas previous studies have predominantly focused on large hail (diameter ≥ 20 mm) events (LHEs) and their yielding conditions, this study was devoted to examining the difference between the LHEs and small hail (2 ≤ diameter < 20 mm) events in their associated atmospheric environments and storm structures. The interesting new insight is that the hailstorms yielding LHEs tend to feature a significantly longer time interval after the rapid increase of vertically integrated liquid and before hailfall. This study can provide a reference for the early warning of the scale of hail, which is one of the difficulties of weather services.
Fast and Slow Responses of the Tropical Pacific to Radiative Forcing in Northern High Latitudes
Authors: Tseng Hung-Yi , Hwang Yen-Ting , Xie Shang-Ping , Tseng Yu-Heng , Kang Sarah M. , Luongo Matthew T. , Eisenman Ian
Published: April 2023

This study investigates the transient evolution of tropical Pacific sea surface temperature (SST) responses to a constant northern high-latitude solar heating in fully coupled CESM 1.2. The study identifies two stages through multiple ensemble runs. 1) In the first 3 years, a hemispherically asymmetric pattern emerges, caused by air–sea interactions associated with the anomalous cross-equatorial Hadley cell. The northern tropics experience warming that is blocked north of the equator by the intertropical convergence zone. The southeast Pacific cooling reaches the equatorial region and is amplified by the equatorial Ekman divergence. 2) Within a decade, the equatorial cooling is replaced by warming in the eastern equatorial basin. The anomalous warming that appears faster than the time scales of the oceanic ventilation is attributed to anomalous meridional heat convergence and weakening of the northern subtropical cell. Our findings highlight the influence of ocean dynamics on the temporal and spatial evolution of tropical SST response to hemispherically asymmetric heating. The initial cooling caused by Ekman divergence delays the arrival of slow warming, while initial wind and temperature anomalies set the stage for the weakening of the subtropical cell. The results have important implications for understanding the evolution of tropical SST patterns in observational records and future climate change simulations, as they show strong interhemispheric temperature asymmetry in the extratropics.
Real-Time Monitoring of Weather Radar Network Calibration and Antenna Pointing
Authors: Louf Valentin , Protat Alain
Published: April 2023

We present an integrated framework that leverages multiple weather radar calibration and monitoring techniques to provide real-time diagnostics on reflectivity calibration, antenna pointing, and dual-polarization moments. This framework uses a volume-matching technique to track the absolute calibration of radar reflectivity with respect to the Global Precipitation Measurement (GPM) spaceborne radar, the relative calibration adjustment (RCA) technique to track relative changes in the radar calibration constant, the solar calibration technique to track daily change in solar power and antenna pointing error, and techniques that track properties of light-rain medium to monitor the differential reflectivity and dual-polarization moments. This framework allows for an evaluation of various calibration and monitoring techniques. For example, we found that a change in the RCA is highly correlated to a change in absolute calibration, with respect to GPM, if a change in antenna pointing can first be ruled out. It is currently monitoring 67+ radars from the Australian radar network. Because of the diverse and evolving nature of the Australian radar network, flexibility and modularity are at the core of the calibration framework. The framework can tailor its diagnostics to the specific characteristics of a radar (band, beamwidth, etc.). Because of its modularity, it can be expanded with new techniques to provide additional diagnostics (e.g., monitoring of radar sensitivity). The results are presented in an interactive dashboard at different level of details for a wide and diverse audience (radar engineers, researchers, forecasters, and management), and it is operational at the Australian Bureau of Meteorology.

Significance Statement

Weather radars, like all instruments, require maintenance and upgrades. Rainfall measurements are highly variable and sensitive to change, and this can lead to inconsistencies within a radar network. Calibration is the process to counteract those inconsistencies. Any calibration requires a fixed standard to which the changed/upgraded radar can be compared. The SCAR calibration framework presented herein makes use of several standards to retrieve a full set of diagnostics about the radar data. We apply these techniques over the entire Australian weather radar network and demonstrate that, by using this integrated approach, absolute calibration can be achieved to within 1 dBZ of reflectivity, antenna pointing can be monitored within 0.1°, and the various measurements of the radars can be quality controlled.
Network of burnout, depression, anxiety, and dropout intention in medical undergraduates
Authors: Peng Pu , Chen Shubao , Hao Yuzhu , He Li , Wang Qianjin , Zhou Yanan , Tang Yi-Yuan , Yang Winson Fuzun , Wu Qiuxia , Liu Tieqiao
Published: April 2023

Background:

Burnout, depression, and anxiety are highly prevalent among medical students, which often leads to their attrition. We aim to assess the inter-relationships of depression, burnout, and anxiety symptoms with dropout intention among Chinese medical undergraduates using the network analysis.

Method:

A total of 3,648 Chinese medical undergraduates were recruited through snowball sampling. Learning burnout scale, 9-item Patient Health Questionnaire (PHQ-9), and General Anxiety Disorder Scale (GAD-7) was used to assess burnout, depression, and anxiety symptoms, respectively. We used the EBICglasso model to estimate the network. We compared the network based on gender, study phase, and clinical experience.

Results:

After removing repeated submissions and incorrect responses to the trap question, 3,536 participants were included in the final analysis. The prevalence of burnout, depression, anxiety, and dropout intention was 38, 62.7, 38.4, and 39% respectively, which is consistent with previous findings. Network analysis suggested that anxiety and depression items clustered together and displayed several strong bridge connections, while burnout items formed another cluster. All the strongest edges were within the respective distress. Cynicism symptoms ‘I am fed up with study’ and ‘I want to study but I feel that studying is boring’ were the most central symptoms, while ‘fatigue’ and ‘worthless’ were the bridge symptoms within the burnout-depression-anxiety network. Other central symptoms included ‘worthless’, ‘I can handle my courses’, ‘nervous’, and ‘uncontrollable worry’. Cynicism symptoms ‘I am interested in my major’ and ‘I feel that the knowledge I have learned is useless’ were mostly related to dropout intention. Gender, study phase, and clinical experience didn’t affect the global strength of the burnout-depression-anxiety network.

Conclusion:

Our results indicated the predominance of cynicism symptoms within the burnout-depression-anxiety network and its substantial impact on dropout intention, suggesting that early detection and intervention for cynicism symptoms in Chinese medical students are in urgent need. Other central and bridge symptoms might also serve as potential targets for the prevention and treatment of burnout, depression, and anxiety among medical students. For example, studies suggest cognitive-behavioral therapy could quickly improve ‘worthless’, which might be beneficial in treating burnout, depression, and anxiety in medical students.
Suicides among Children and Adolescents in Paraguay: An 18-year National Exploratory Study (2004–2022)
Authors: Torales Julio , Barrios Iván , Tullo-Gómez Juan Edgar , Melgarejo Osvaldo , Gómez Nora , Riego Viviana , Navarro Rodrigo , García Oscar , Figueredo Pamela , Almirón-Santacruz José , Caycho-Rodríguez Tomás , Castaldelli-Maia João Mauricio , Ventriglio Antonio
Published: April 2023

Background:

Suicide and suicide attempts are impacting events for patients and their relatives, and these behaviors are still taboo among adults and may be even more traumatic when involving children and adolescents.

Aim:

In this study we aimed to describe suicide rates among children and adolescents in Paraguay over the last decades as well as associated factors such as sociodemographic characteristics and methods used for suicide.

Methods:

This was an observational and exploratory study describing the frequency and characteristics of suicide among children and adolescents in Paraguay between 2004 and 2022. Official records of all deaths by suicide were reviewed, and statistical analyses were performed. In addition, an attempt was made to predict the number of suicides in the next 5 years using a mathematical model based on simple linear regression.

Results:

In the 18-year period observed, 940 suicides among children and adolescents were recorded. The mean age was 15.05 ± 1.8 years old. Of these, 51.17% were male, 74.6% were from urban areas, and 22.2% were from the Greater Asunción and Central Department of Paraguay. The most frequently used method of suicide was intentional self-inflicted injury by hanging, strangulation, or suffocation, which all represented 75.3% of the cases. Our mathematical modeling based on simple linear regression determined that the expected yearly number of national suicides in the pediatric population for the following years, from 2023 to 2027, will range between 72 and 81.

Conclusion:

This study is the first large national epidemiological report on the emerging issue of suicide among children and adolescents in Paraguay. It may be a relevant source of information for mental health professionals, health authorities, and decision makers to develop national prevention strategies and actions against suicide among youths.
“Verbs are a Tragedy”: Poetics of Refusal From the Black Diaspora
Authors: Khaymaz Sheyda Aisha
Published: April 2023

“Language [is] a foreign anguish,” once declared Afro-Caribbean diasporic poet NourbeSe Philip. Philip’s sentiment holds true predominantly for those who write within Anglophone spheres, yet cannot relay their anguish to their mothers in English. This article argues that the English language, as a diasporic tongue, is a limited and limiting entity that precludes the rich spectrum of expression of diasporic consciousness. A number of poets from the Black Diaspora have sought to transgress the boundaries of their language, and in turn produced strategies for liberation. In this article, I analyze and compare the work of NourbeSe Philip, Dionne Brand, June Jordan, and Claire Harris to demonstrate how the desire for liberation from coloniality has produced linguistically deconstructive impulses in these poets. Their resulting oeuvre is characterized by a distinctive refusal that tends toward fragmentation, incompleteness, and a sense of strangeness.
Black, Brown and Asian cultural workers, creativity and activism: The ambivalence of digital self-branding practices
Authors: Sobande Francesca , Hesmondhalgh David , Saha Anamik
Published: April 2023

How do cultural and creative workers respond to racism and the politics of representation and respectability in the digital age? In what ways do they engage in forms of community-building and solidarity-making, while managing pressures to build digital presence and personal brands? This article seeks to address these questions via 30 in-depth interviews with Black, Brown and Asian (BBA) workers in the UK cultural and creative industries (CCIs). Focusing on the ambivalence of digital self-branding practices, our work builds on scholarship on inequalities in the CCIs, and on platformization and race. We organize our findings regarding the experiences and values of these workers into three main themes: the positive potential these workers find in the capacity of digital media technologies for forging community and solidarity; the benefits and limitations of using digital media technologies to communicate counternarratives, including exposure of discrimination in CCIs, and adapting and ‘gaming’ features such as recommendation algorithms; and how they experience and navigate felt pressures to self-brand in contemporary digital contexts. We find a marked ambivalence in the reported experiences of these workers, which generatively complicates existing accounts of digital technology, algorithmic struggles and the UK’s CCIs.
Can Work Time Fragmentation Influence Workers’ Subjective Time Pressure? The Roles of Gender and Parenthood
Authors: Lu Zhuofei
Published: April 2023

This article investigates how the fragmentation of work time influences subjective time pressure, and how this relationship varies across gender and parenthood status. This is an important question that has been neglected by previous studies. Using the latest UK time-use data ( N = 620) from 2020 to 2021 and Ordinary Least Squares regressions, the study finds that work time fragmentation generally predicts more subjective time pressure. Specifically, work time fragmentation is found to increase subjective time pressure more among women without children than mothers. However, this effect is inverted among men, as the fragmentation of work time predicts more subjective time pressure among fathers but not among men without children. These findings provide a nuanced understanding of the adverse consequences of ‘role switching’ and ‘work schedule instability’ and their interaction with gender and parenthood. Accordingly, future research should consider work time fragmentation as a vital indicator of job and life quality.
Gentrifying with family wealth: Parental gifts and neighbourhood sorting among young adult owner-occupants
Authors: van Gent Wouter , Damhuis Rik , Musterd Sako
Published: April 2023

This paper assesses the role of parental gifts in neighbourhood sorting among young adult homebuyers. We make use of high-quality individual-level registry data for two large urban metropolitan areas in the Netherlands. While previous studies have shown that young adults receiving gifts purchase more expensive housing, little is known about the role of gifts in where young adults buy. Our study finds that parental gifts flow into the housing market in a spatially-uneven way. Movers supported by substantial parental gifts are more likely to enter owner-occupied housing in high-status and gentrifying urban neighbourhoods compared to movers without gifts. This study shows that this can only partially be explained by household and parental characteristics and by the uneven distribution of housing values. The remaining effect suggests that parental gifts also play a role in trade-offs regarding spatial residential decision-making. The conclusion discusses the ramifications of our findings for debates on (re)production of class and intra-generational inequalities through housing, and provides avenues for further research.
Delivering common property in Chinese contractual communities: Law, power and practice
Authors: Jia Yiru , Morrison Nicky , Sielker Franziska
Published: April 2023

This paper examines how common property is produced and delineated in contractual communities in China. Shanghai, one of the most developed Chinese cities with a burgeoning housing market, is used as a case study. The research analyses the power relations between land, construction and housing departments within Shanghai district governments and with developers, specifically, during the development phases of land leasing, construction permission and ownership registration. Drawing on the theoretical framework of new institutionalism, and its conception of path dependency in urban space, the article sheds light on what has led to the infringement on homeowners’ common property by developers. In a weak legal and regulatory system for property development, the departments within district governments shirk responsibility to each other, whereas developers hold considerable power. The article concludes that common property bears the imprint of power dynamics set in motion in the development phase and thus requires greater recognition.
The relevance of job accessibility to labour market outcomes: Evidence for the São Paulo metropolitan region
Authors: Batista Duarte Leandro , da Mota Silveira Neto Raul , Firmino Costa da Silva Diego
Published: April 2023

Focusing on the case of the São Paulo Metropolitan Region, the largest urban centre in South America, this study provides evidence of the effect of job accessibility on three different labour market dimensions: participation, employment and informality. The evidence is obtained by combining information about household and employment locations and using a probit model together with an instrumental variable strategy. The results indicate that better job accessibility increases the probability of employment for both males and especially females, with employment probability elasticities of about 0.05% and 0.15%, respectively. In addition, we found that better access to jobs positively influences the probability of participation only for females. The set of evidence favours policies promoting higher residential density, transport infrastructure, and family support services.