bluuebunny/crossref_metadata_2025 huggingface dataset:
Content Analysis of Brazilian Mobile Applications Targeting Blood Pressure Management: A Systematic Search
Authors: Johann Eduardo Braghini , Baggio Marcelo , Pauli Nicolle Abreu , Dilli Artur , Ilkiu Rafael Teixeira , Ritti-Dias Raphael Mendes , Gerage Aline Mendes
Published: February 2025

Abstract Background Several mobile applications have been developed to assist in managing hypertension, but little is known about their quality in the Brazilian scenario. Objective To identify and analyze the quality of the apps targeting blood pressure (BP) management available in Portuguese. Methods A systematic search was carried out through Brazilian virtual app stores in the Android and iOS platforms from November 2021 to March 2022, with an update in March 2024. The search was based on the standards of systematic review (PRISMA), using predefined keywords, including apps in Portuguese, free and available for use during the search. Three independent reviewers analyzed the apps using the five-point Mobile App Rating Scale (MARS), and for the presence of tools/content related to the BP control. Results Fifty-six applications met the criteria for data extraction. The most prevalent tool was the recording of BP values (98%). The tool for adherence to medication and reminders to their use was present in only 29% and 34% of the APPs, respectively. The mean overall MARS score was 3.4 ± 0.74 and 3.1 ± 0.61 for Android and iOS APPs, respectively, which classified then as acceptable. The best rated item was “functionality” for both Android and iOS apps. Conclusion The present study identified numerous apps with acceptable quality aimed at monitoring BP. However, most of them did not include important factors related to disease control, particularly regarding treatment adherence, physical activity and presence of comorbidities.
Revolutionizing Healthcare Efficiency: A PHP and MySQL-Powered Hospital Management System
Authors: - Syed Farhan Ashraf , - Vaibhav U Navalagi , - Shreeram Shivabasu Badagandi , - Nagaraja G S
Published: February 2025

Hospital Management Systems (HMS) play a critical role in modern healthcare, ensuring streamlined operations, efficient resource management, and improved patient outcomes. Traditional HMS implementations often suffer from
inefficiencies such as manual data entry, redundant workflows, and lack of integration across departments. This study presents an AI-enhanced HMS leveraging XAMPP, MySQL, and web technologies to automate administrative tasks and optimize decision-making. By centralizing operations, the system improves appointment scheduling, billing accuracy, inventory control, and overall hospital workflow. The system design incorporates principles of management and economics, focusing on resource allocation, cost-benefit analysis, and scalability. Performance evaluations reveal a significant reduction in scheduling delays, enhanced data retrieval speeds, and a usability score above 90%. The findings highlight the potential for AI-driven healthcare solutions to reduce operational inefficiencies and improve patient care.
Cooperatives: Socio-Economic and Cultural Identity of Indian Ethos
Authors: - C Vijaya
Published: February 2025

Cooperatives have long been integral to India's socio-economic and cultural fabric, reflecting the nation's deep-rooted traditions of collective effort, mutual support, and community welfare. This paper examines the historical evolution, cultural significance, and economic contributions of cooperatives in India, tracing their foundations to traditional practices like joint family systems and local self-governance. It highlights how cooperatives have facilitated rural development, women's empowerment, and social equity, becoming powerful tools for sustainable growth. Despite challenges such as political interference and globalization, cooperatives remain central to India's vision of inclusive development, blending age-old cultural values with modern economic practices. This study underscores their role as a foundation for India's cultural identity and a model for collective progress.
PERBANDINGAN TINGKAT KECEMASAN SEBELUM DAN SETELAH INTERVENSI EFFLURAGE MASSAGE DAN SUPPORT SYSTEM SUAMI SAAT KEHAMILAN TRIMESTER III SAMPAI SETELAH PROSES INTRANATAL PADA IBU PRIMIGRAVIDA DI KLINIK BIDAN MUTIARA PURWAKARTA
Authors: Anggi Geuis , Ati Nung
Published: February 2025

Kecemasan   merupakan  masalah  psikologi  yang  sering  dan  banyak  dialami  oleh  ibu  hamil  terutama primigravida  trimester  III  sebetulnya  kecemasan  ini  bersifat  fisiologis  namun  jika  tidak  teratasi  dapat berdampak  buruk baik pada kesehatan ibu maupun janin, oleh karena itu perlu ada intervensi  yang dapat mencegah serta mengatasi kecemasan. Intervensi yang dapat digunakan untuk mencegah dan mengatasi kecemasan adalah intervensi farmakologi dan non farmakologi. Intervensi non farmakologi yang sering digunakan adalah pijat, latihan nafas, aromaterapi, kompres hangat, terapi musik dan dukungan suami. Teknik non farmakologi  yang dipilih dalam penelitian  ini adalah pijat dan dukungan  suami. intervensi  ini dipilih karena menurut penelitian sebelumnya sangat efektif, mudah, murah, tidak memerlukan sertifikasi khusus dan masuk ke dalam program pemerintah “asuhan sayang ibu”. Tujuan penelitian untuk mengetahui perbandingan tingkat  kecemasan  sebelum  dan setelah  intervensi.  Metode  penelitian  yang di gunakan  Pre-Experimental dengan  one  group  pretest  and  posttest  design.  Subjek  penelitian  adalah  ibu  hamil  trimester  III.  Subjek intervensi  adalah  seluruh  subjek  penelitian  dan  suami.  Teknik  pengambilan  sampel  dengan  consecutive sampling. Jumlah sampel 25 (n=25). Pengambilan data dilakukan April sampai September 2025. Pengukuran kecemasan  dengan  menggunakan  kuisioner  PASS (Perinatal Anxiety Screnning  Scale).  Hasil  uji validitas p<0,05  dan reliabilitas  0,06. Analisa  data, menggunakan  Wilcoxon. Hasil Penelitian  menunjukkan  tingkat kecemasan sebelum intervensi, mengalami kecemasan berat sebanyak 20 orang (80%) dengan skor nilai 28-41 sedangkan setelah dilakukan intervensi mengalami kecemasan ringan sebanyak 21 orang (84%) dengan skor 14-20, menunjukan adanya penurunan skor kecemasan sebesar 10,2 (95% IK 8–12). Terdapat perbedaan signifikan rerata tingkat kecemasan sebelum dan setelah intervensi dengan nilai p value 0,001.
A review on leukemia: advances in diagnosis, treatment and prognosis
Authors: N Hemalatha , M Sowjanya , Y Prapurna Chandra , Venugopalaiah Penabaka , Yerikala Ramesh
Published: February 2025

Cancer is a disease of altered signalling and metabolism, causing uncontrolled division and survival of transformed cells. A host of molecules, factors, and conditions have been designated as underlying causes for the inception and progression of the disease. An enormous amount of data is available, system-wide interaction networks of the genes and proteins are generated over the years and have now reached up to a level of saturation, where we need to shift our focus to the more advanced and comprehensive methods and approaches of data analysis and visualization. Even with the availability of enormous literature on this one of the most pressing pathological conditions, a successful cure of the disease seems to be obscure. New treatment plans, like immunotherapy and precision medicine, are being employed for different studies. Nevertheless, their actual benefits to the patients would be known only after the evaluation of clinical data over the next few years. Therefore, we need to look at few fundamental challenges that should be addressed in more depth before we could devise better, rigorous and comprehensive treatment plans and may successfully reach a possible cure of the disease. This article aims at bringing attention towards some fundamental gaps in our approach towards the disease that leads to failure in devising successful therapeutics.
O Referente Curricular Gaúcho e o ensino de Álgebra para crianças
Authors: Barcellos Veronica Cunha , Beck Vinicius Carvalho , Freitas Fabricio Monte , Silva João Alberto da
Published: February 2025

A Base Nacional Comum Curricular - BNCC oficializou o ensino de Álgebra para crianças no contexto brasileiro. Os impactos dessa política refletem-se nos currículos dos estados e municípios. Neste artigo apresentamos um estudo documental, onde analisamos a materialização do ensino de Álgebra. A partir de uma análise descritiva e sustentados nas ideias de Basil Berstein, analisamos as habilidades descritas no currículo, e nas Matrizes de Referência do ano de 2023, com a intenção de complementar as orientações pedagógicas no contexto pós-pandêmico. Os dados indicam que a recontextualização da BNCC para o currículo gaúcho é mínima, apresentando pequenas modifições. Elas trazem pouca orientação e uma visão estreita dos conteúdos de Álgebra. Assim, as matrizes reforçam a ideia de que Matemática e Álgebra, em especial, possuem um status superior de dificuldade e importância, não sendo necessário o trabalho didático e pedagógico articulado com outros temas e ações.
O documento curricular referencial da Bahia e os textos do discurso instrucional do caderno de matemática para os anos iniciais
Authors: Luna Ana Virginia de Almeida , Almeida Larissa Santana de , Silva Vanessa
Published: February 2025

Esta pesquisa teve como objetivo analisar as regras discursivas que regulam os textos do discurso instrucional de álgebra no documento curricular referencial da Bahia (DCRB) e no Caderno de Matemática deste documento, dos anos iniciais do Ensino Fundamental. O estudo envolve uma abordagem qualitativa e foi desenvolvido numa perspectiva sociológica, por meio da linguagem de descrição, modelo de investigação proposto por Basil Bernstein. A pesquisa foi realizada a partir da análise documental do DCRB e do caderno de matemática, do DCRB. Por meio da análise foram levantadas quatro categorias, que possibilitaram a discussão dos resultados, a saber: a primeira, organização de orientações metodológicas; a segunda, seleção de objetos de conhecimento e habilidades; a terceira, sequenciamento e ritmo do texto do discurso instrucional algébrico, e a quarta, avaliação da álgebra e seus critérios. Com os resultados foi possível a identificação de inovações, possibilidades e desafios apresentados, em relação às três categorias discutidas. Com isso, vale considerar a importância da formação docente sobre o novo documento curricular e de levar em consideração outros estudos, que possibilitem a ampliação do conhecimento sobre as dúvidas em tais processos formativos.
Sandra Magina e seu percurso para o desenvolvimento de pesquisas no pensamento algébrico
Authors: Luna Ana Virginia de Almeida , Silva João Alberto da , Alencar Edvonete Souza de , Tomascheski Tchaila Regina Santino
Published: February 2025

Sandra Maria Pinto Magina realizou o primeiro pós-doutoramento na Universidade de Lisboa (2006) e o segundo na Universidade de Salamanca (2019-2020). Concluiu o doutorado em Mathematics Education pela University of London em 1994. Foi docente da Pontifícia Universidade Católica de São Paulo entre 1994 e 2014, desligando-se dela como professora titular.
O pensamento algébrico no documento curricular de Roraima nos anos iniciais do Ensino Fundamental
Authors: Alencar Edvonete Souza de
Published: February 2025

O presente artigo tem como objetivo identificar como o pensamento algébrico tem sido abordado no documento curricular do estado de Roraima nos anos iniciais do Ensino Fundamental. Essa investigação faz parte de uma pesquisa maior que contempla analisar como o pensamento algébrico tem sido apresentado nos documentos curriculares dos diferentes estados brasileiros. Para o seu desenvolvimento realizamos uma análise documental do documento que rege a educação estadual de Roraima. A seleção por esse estado se deu por este estar no norte do país, em uma região extrema e afastada dos grandes centros. Salientamos ainda que o fato desse estar em região fronteiriça e ter nos últimos anos recebidos um considerável número de refugiados, nos instigou a realização dessa investigação.    Como resultados nas análises identificamos que o eixo segue as diretrizes da Base Nacional Comum Curricular e nota-se poucas adaptações e sugestões para a flexibilidade regional.
Cross-linguistics difference in disjunction in two-dimensional semantics
Authors: Yagi Yusuke
Published: February 2025

Disjunction, expressed by or in English, is a primary connective available in natural language. It was traditionally analyzed as the counterparts of the Boolean connectives ∨ (e.g., Montague 1973), but subsequent studies revealed a number of inadequacies in this approach, which led to the ‘dynamic turn’ in natural language semantics (Karttunen 1974; Heim 1982; et seq). However, the empirical base of the literature almost exclusively comprises examples of English. The cross-linguistic (in)adequacy of the theory has yet to be investigated. This paper addresses this research gap by inspecting disjunction in Japanese. More specifically, this paper examines the (non-)replicability of the observations that support the dynamic analysis for English ‘φ or ψ’ that hardwires the local context ¬φ. I argue that Japanese disjunction exhibits some kinds of evidence for the local context, but not others.
Innovation of Jalan Rusak Lapor Dewe Application at the East Java Bina Marga Public Works Office
Authors: Putri Thersa Armenia , Harmawan Bagus Nuari
Published: February 2025

The East Java Bina Marga Public Works Office created an innovation called JALAK LOEWE (Jalan Rusak Lapor Dewe). The innovation is used to facilitate the community in complaining about road damage. This research aims to discuss the public service innovation launched by the East Java Bina Marga Public Works Office through the JALAK LOEWE application. The research method used in this research is qualitative research with a case study approach. In obtaining data, researchers collect through observation, interviews, and documentation. The results of this study refer to seven innovations in digital public services in (Bertot, Estevez, & Janowski, 2016), namely: Transparent, Participatory, Anticipatory, Co-Created, Personalized, Context-aware, Context-smart. Based on the findings obtained, it explains that there are several indicators that have been running quite well, but there are still other indicators that have not been fulfilled.
The Indirect Comparison of Brand Image Perception of Share a Coke with Campaign
Authors: Tanasyah Yacub , Berto Agustinus Rusdianto , Murwani Endah
Published: February 2025

The success of the marketing campaign of “Share a Coke With” has been globally known as one of the personalized campaigns with some popular individual names. This act of corporate communication has made the Coca-Cola Company even stronger as a multinational company. The usage of individual names has created a stronger bond between the brand and the audience. This qualitative research examines to what extend the brand image of Coca-Cola has affected the perception of its audience as it will have the implications of the economic and the social effects to the brand. The qualitative approach is used through the content analysis technique to some residents who were born and raised in Surabaya as of 2024, with 6 participants participating by the purposive sampling. This research examines the brand image by its favourability, strength, and uniqueness associated to Coca-Cola as a brand. Results has indicated a significant influence to the brand image and the personalized campaign. This research has underscored the importance in building consumer relations, strengthening the marketing strategy, and shaping brand image in a more complex world full of messages.
Household Destroyed Due to Husband's Brother's Intervention
Authors: Al Manar Irwansyah , Thabrani Abdul Mukhti , Yaqin Nurul
Published: February 2025

Marital relationships are always related to harmony and balance is an important cornerstone. However, often, interference from third parties can become a problem that damages and threatens the stability of a household.  This study aims to explore the detrimental effects of such interference on marital stability, emphasizing the importance of communication, boundaries, and mutual respect in marital relationships to overcome challenges within the household. This research uses a qualitative approach. Based on the researchers' findings, one of the common causes of marital breakdown is interference from the husband's relatives or family who are too dominant in the couple's household affairs. The role of the husband's siblings, be they younger siblings, parents, or even extended family, is often an important question in marriage dynamics.
Servant Leadership and Innovative Work Behavior: The Role of Meaningful Work and Strengths Use
Authors: Mardhiyyah Thaib Rosa Nabiila , Parahyanti Endang
Published: February 2025

Amidst the current high global dynamics and volatility, BUMN as the spearhead of the national economy needs to strengthen its performance through innovation. However, innovation itself is still a challenge that needs to be overcome by BUMN to maximize its potential. This study aims to examine the mediating role of meaningfulness of work in the relationship between service leadership and employee innovative behavior, as well as the moderating role of the use of power. The measuring instruments used in this study consisted of a scale of innovative work behavior (α = 0.954), service leadership (α = 0.771), meaningfulness of work (α = 0.925), and use of power (α = 0.893). This study involved 366 BUMN employees who had direct superiors and were aged 20-40 years, and were selected using convenience sampling techniques. Data analysis using the PROCESS model 4 and model 14 procedures showed that meaningfulness of work mediated the relationship between service leadership and innovative work behavior. However, this study did not find a moderating effect of the use of power on the mediation effect.
Developing a Low-Sugar Dessert Business Idea with a Design Thinking Approach
Authors: Aripradono Heru Wijayanto , Peiwen Sally Tan
Published: February 2025

This research raises the issue of high sugar consumption which has a negative impact on public health. Data shows that sugar consumption in Indonesia is very high, making it one of the countries with the largest sugar consumption in the world. To overcome this problem, establishing a low-sugar dessert business is a very relevant solution. In this research, researchers used a qualitative descriptive method by adopting the Design Thinking approach as the main approach. Design Thinking is used to understand consumer needs and preferences and develop dessert products that are low in sugar but still delicious and satisfying. This method involves five stages, namely, empathy, defining the problem, ideation, prototyping, and testing. The research results show that the Design Thinking approach is successful in creating low-sugar dessert products that are well received by the market. The products resulting from this process not only meet health criteria but also satisfy consumer tastes, making them an attractive alternative to healthier desserts. This research also provides valuable insight into the market potential for low-sugar desserts and supports efforts to increase awareness of healthy eating among the public.
Leadership Training Program at Faculty of Psychology, Bosowa University
Authors: Purwasetiawatik Titin Florentina , Ibrahim Misykat Malik , Rasyid Muhammad Nur Akbar
Published: February 2025

This study aims to describe the implementation of the Kirkpatrick model evaluation of levels 1, 2 and 3 of the student leadership training programs at the Faculty of Psychology, Bosowa University, Makassar. This study uses a mix method (quantitative-qualitative). This study involved 33 participants. Data were collected through questionnaires, interviews, observations, and documentation. The results of the study showed that level 1, participant reactions measured by a Kirkpatrick reaction sheet questionnaire, that leadership training participants were satisfied with the available schedule components and were very satisfied with the committee components, facilities, content, speakers and materials. At level 2, which was measured through a pre-post t-test, there was a change in participant knowledge and skills with a significant average learning evaluation value. At level 3, which was described from the interview results, there was a change in behavior in 4 components, namely personality, interpersonal communication, cooperation skills and leadership skills, although the changes were not significantly consistent for 33 participants within 1.5 months. The Kirkpatrick evaluation model is effective in assessing the level of participant satisfaction, increased knowledge and changes in behavior of leadership training participants. The leadership training program is very effective to be carried out continuously every year as an effort to shape the character of students who are ethical, innovative, broad-minded, and have global competitiveness. The material provided is more varied, adjusted to the development and context of the generation. Carrying out activities according to the training guidelines and inviting more students to actively participate.
Strategy for Improving Rice Agroindustry Production Processes Based on Green Value Stream Mapping
Authors: Yulianto Kiki , Ismanto Sahadi Didi
Published: February 2025

The rice agroindustry faces challenges due to high inefficiency and negative environmental impacts from excessive resource use. This study aims to improve production processes using Green Value Stream Mapping (GVSM) to reduce non-value-added activities and optimize natural resource usage. The research involves literature review, field observation, interviews, brainstorming, and expert opinions. The production process from seeds to distribution consumes 265 kWh of energy and 8 million liters of water, generates 10,532 kg of waste, and impacts 1.2 hectares of biodiversity. The study confirms that the GVSM strategy enhances operational efficiency and contributes to broader environmental sustainability. The research provides practical guidelines for rice agroindustry companies to implement more environmentally friendly and efficient production practices.
The Effect of Residence in Highlands and Industrial Areas on the Incidence of Hypertension
Authors: Hasabi Faris , Romadhon Yusuf Alam
Published: February 2025

Hypertension is a measurement of systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg. According to WHO data, the number of adults with hypertension has doubled from 650 million in 1990 to 1.3 billion in 2019. The prevalence in Indonesia in 2018 was around 34.1% and in Kendal it continues to increase every year. People who live in the highlands are at risk of developing hypertension due to differences in the body's physiological processes with people who live in the lowlands. Various types of air pollutants such as particulate matter (PM) are widely recorded as being associated with cardiovascular disease, especially in industrial areas and big cities. This study is to analyze the effect of proximity to highland residences and industrial areas on the incidence of hypertension in Kendal Regency. This study uses observational analytics with a cross-sectional research design. The sampling technique used is purposive sampling. Univariate and bivariate analysis using Chi-Square test. Significant results were obtained based on the Chi-Square test on the effect of residence in the highlands and industrial areas on the occurrence of hypertension with a p-value of 0.000 ( p-value <0.05). This study shows the effect of proximity to residence in the highlands and industrial areas on the occurrence of hypertension in Kendal Regency.
Relationship Between Antenatal Care History and Parenting Patterns with the Incidence of Stunting in Toddlers
Authors: Harumi Ani Media , Wardani Novita Eka Kusuma , Sholikah Siti Mar’atus
Published: February 2025

This study aims to analyze the relationship between antenatal care history and parenting patterns in toddlers with the incidence of stunting in the Wonoayu Health Center area, Sidoarjo. Through a quantitative research design with a cross-sectional approach, data were collected from 120 mothers who have toddlers, using questionnaires and observation sheets. The results of the analysis showed a significant relationship between antenatal care history and parenting patterns with the incidence of stunting. Statistical tests with logistic regression showed that improvements in antenatal care and parenting patterns can reduce the risk of stunting in toddlers. This study provides important insights into the importance of early intervention and education for mothers to improve child health and prevent stunting in the community. Thus, recommendations to strengthen maternal and child health programs, as well as increase public awareness of good parenting patterns, are needed to support optimal growth and development of toddlers.
Design of Distributor Performance Measurement System Using Balanced Score Card Method
Authors: Apriliyanto Deri , Syairudin Bambang
Published: February 2025

The research designs an extensive performance measurement system for distributors of PT Semen Indonesia Tbk by employing the Balanced Scorecard (BSC) methodology. The research examines how the company has struggled to reach Revenue, Sales Volume and EBITDA targets because bulk cement sales experienced a 13.5% rise in demand yet did not fulfill RKAP expectations. The research targets distributor performance assessment since distributors substantially boost company sales beyond direct sales activities. BSC provides organizations with a method to create distributor-level metrics that support corporate objectives through financial and customer and internal process and learning and growth criteria. The study extends key performance indicators (KPIs) from the Corporate Sales Group through multiple levels to distributor performance metrics which include volume while measuring revenue together with market share and customer satisfaction as well as operational efficiency. The introduction of this system during 2024 effectively boosted distributor performance through its 101.6% success in meeting sales targets along with 0.2% higher market share achievement. The research offers final recommendations that support ongoing personnel training as well as periodic KPI socialization alongside plans for additional studies to advance performance assessment systems across the Corporate Sales Group.
Типы ценностно-смыслового отношения довузовской и вузовской молодежи к низовой коррупции в форме взяточничества: учебное пособие на модульной основе
Authors: Кибальченко Ирина Александровна , Джанерьян Светлана Тиграновна
Published: February 2025

Систематизированы и обобщены теоретико-эмпирические исследования отношения учащейся молодежи к низовой коррупции в форме взяточничества. Рассмотрены трактовки, строение, типы ценностно-смыслового отношения к взяточничеству. Раскрыты особенности каждого из типов этого отношения у довузовской (старшеклассники и учащиеся колледжей) и вузовской (студенты) молодежи. В соответствии со спецификой типа отношения и статуса его субъектов систематизированы антикоррупционные мероприятия. Содержание учебного пособия изложено на модульной основе, включает контрольные вопросы, проектные и тестовые задания. Учебное пособие рассчитано на студентов, аспирантов, преподавателей средних и высших учебных заведений, специалистов, осуществляющих психологическое сопровождение обучающихся в школах, колледжах и вузах.
Metformin as a protective substance against cisplatin-induced acute renal injury in rats
Authors: Badawi Marwa , Awwad Alenezy  , Saad H. Elshafey  , Naglaa A. Bayomy  , Mohamed M. Mosaed  , Hanan A. Elgendy  , Mohamed M. Ismail  , Abdelrahman Alyan
Published: February 2025

Despite the efficacy of cisplatin as a chemotherapeutic agent against various cancers, its clinical utility is limited by serious adverse reactions including nephrotoxicity. Various studies revealed that metformin is more than a simple antidiabetic agent. Metformin was found to improve inflammatory, and fibrotic renal damage. The present study aims to investigate the protective effect of metformin against cisplatin-induced acute renal injury in rats. 40 adult male albino rats were divided into 4 groups with 10 rats in each group. Group I (control group). Group ІІ animals receive metformin at a dose of 200 mg/kg/day by oral gavage for 10 days. Group ІІI animals receive a single injection of cisplatin intraperitoneally at a dose of 8 mg/kg. Group ІV animals receive cisplatin Plus metformin. At the end of the experiment, the kidneys were removed, weighed, and sampled for histopathological, immunohistochemical, and biochemical studies. Metformin decreased elevated serum creatinine, blood urea nitrogen, renal malondialdehyde (MDA) and immunoexpression of the proapoptotic protein (Bax) induced by cisplatin. It increased reduced glutathione (GSH), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and immunoexpression of the antiapoptotic protein (Bcl2). It also ameliorated the morphological changes induced by cisplatin. Cisplatin has nephrotoxic effects as indicated by biochemical, histological, and immunohistochemical alterations. Metformin was found to have protective effects against cisplatin-induced nephrotoxicity through the improvement of kidney function, and histopathological changes in rat kidney.
Larvicidal efficacy of Martynia annua plant extract against major Culicinae vectors in the Greater Hyderabad region of Telangana state
Authors: Madpathi Siddaiah , Bannoth Reddya Naik
Published: February 2025

The impact of mosquito-borne diseases extends beyond just health concerns, affecting the overall well-being and economic stability of communities, particularly in developing nations such as India. The World Health Organization (WHO) emphasizes the importance of controlling mosquito populations as a more effective approach compared to relying solely on pharmaceutical interventions. With the rising costs and increasing resistance to traditional drugs, researchers are exploring innovative solutions to combat mosquito-borne illnesses, with plant-based mosquitocides emerging as a promising alternative to synthetic insecticides. This implies that Martynia annua could serve as a viable natural larvicide against four disease-carrying mosquito vectors (Aedes aegypti, Ae. albopictus, Culex quinquefasciatus, and Cx. gelidus), offering a promising solution for disease prevention in humans. The study findings revealed that Martynia annua plant extract exhibited larvicidal properties, showing LC50 values of 82.31, 127.24, 126.48, and 37.34 μg/mL, and the LC90 values were 203.61, 270.01, 312.59, and 99.67 μg/mL for the tested mosquito species. Additional testing is necessary to determine the causes of larval mortality at a molecular level, despite the positive outcomes observed in laboratory experiments. Furthermore, extensive field investigations are essential to gain a deeper understanding of the toxic effects of plant extract on a larger scale.
Lysathia flavipes and Lysathia cilliersae Cabrera sp. nov. (Coleoptera, Chrysomelidae): genetic and morphological unravelling of biocontrol agents for two invasive aquatic plants
Authors: Faltlhauser Ana C. , Cabrera Nora , Hernández M. Cristina , Sánchez Restrepo Andrés F. , Hill Martin , Sosa Alejandro J.
Published: February 2025

In the search for specific natural enemies to control two invasive aquatic plants (IAP) from South America, Ludwigia grandiflora subsp. hexapetala (Onagraceae) and Myriophyllum aquaticum (Haloragaceae), taxonomic challenges associated with two Lysathia Bechyné, 1959 (Chrysomelidae; Alticini) species had to be resolved. Lysathia flavipes (Boheman, 1859) exhibits significant morphological variation, causes heavy damage to both IAPs, and may represent more than one species due to the phylogenetic gap between hosts. Additionally, an undescribed Lysathia species (previously published as Lysathia sp.), sourced from Brazil, has been successfully used as a control agent for M. aquaticum in South Africa since 1994. An integrative taxonomic approach combining genetic and morphological analyses was employed. A lectotype and paralectotypes for Graptodera flavipes Boheman, 1859 are here designated. Phylogenetic studies revealed that L. flavipes had greater genetic and morphological variation than originally described, and no evidence suggested that L. flavipes represented a species complex associated with its host plants. As a result, the species description was expanded. On the other hand, genetic and morphological differences such as body size, colouration, and genital structures further supported the description of Lysathia cilliersae Cabrera, sp. nov. and its differentiation from other closely related species, including L. flavipes and L. ludoviciana (Fall, 1910). Specimens of L. cilliersaesp. nov. collected in Misiones, Argentina, matched those from South Africa. Genetic sequences correlated with morphological vouchers, images, and illustrations of morphology and genitalia, as well as new distribution records, are provided. This research contributes to the taxonomic knowledge of the Lysathia genus and supports accurate species identification in applied entomological contexts, such as biological control programmes.
Introduction. De l’évidence à l’effraction du quotidien : vivre et pe(a)nser la vie quotidienne avec autrui, en période de pandémie
Authors: Bouvier-Müh Christine
Published: February 2025

Comment rendre compte et prendre la mesure des bouleversements sociaux, sociétaux et environnementaux que nous avons vécus au plus intime de nous-même, du corps et de la psyché, à des échelles inédites et difficilement représentables, à l’issue de cette longue période de pandémie ? De quelle hébétude nous éveillons-nous, deux ans plus tard ? Il s’agit ici et maintenant de trouver la bonne distance ou l’angle d’attaque suffisamment préparé, du côté de la métaphore, afin de rendre compte d’une réalité empirique dont nous commençons seulement à apprécier et observer les effets : tant sur le sujet que dans les modalités de (re)constitution et transformation du lien social. Parce qu’il est inscrit dans la parole et doté du logos lui permettant d’habiter le monde, l’autre reste l’horizon du sujet. En ce sens, nous ne sommes pas seuls, je ne suis pas seul(e), tel un être sur lui-même replié. Je suis un parmi les autres, et cette pluralité m’ invite à innover, à inventer. Car il s’agit maintenant de consentir à la liberté pour tous et de bâtir, faire société au moment du réveil, être les garants d’une parole qui engage ce que l’on nomme l’humanité. Discipline  : philosophie
L’interdisciplinarité dans un travail de recherche en théologie et en philosophie
Authors: Bourgine Benoît
Published: February 2025

Parmi les nombreux problèmes posés par l’interdisciplinarité en théologie et en philosophie, la présente contribution examine les questions relatives au lieu de rencontre des disciplines, à la nécessité de l’interdisciplinarité, au dialogue entre philosophie et théologie, à l’interdisciplinarité interne à la théologie, et enfin à l’interdisciplinarité dans le dialogue de la théologie avec d’autres rationalités (sciences des religions, sciences humaines et sociales, sciences naturelles). Disciplines  : théologie , philosophie
Comment conjuguer les disciplines scientifiques ?
Authors: Quiviger Pierre-Yves
Published: February 2025

Dans cette retranscription de conférence, l’auteur part de sa propre expérience de philosophe du droit pour définir l’interdisciplinarité comme un dialogue entre disciplines reposant sur des piliers épistémologique et intersubjectif. Il convient toutefois de distinguer trois conceptions différentes. La pluridisciplinarité (ou multidisciplinarité) associe plusieurs disciplines, chacune demeurant autonome. L’interdisciplinarité constitue quant à elle une approche dynamique car les disciplines y voient leur manière d’appréhender un objet être modifiée par la confrontation avec les usages d’une autre discipline. Enfin, la transdisciplinarité traverse plusieurs disciplines mais elle les transcende également en œuvrant à la construction d’une nouvelle méthodologie. Le hiatus observable entre les préoccupations interdisciplinaires exprimées par beaucoup d’équipes de recherche et le peu de pratiques concrètes s’explique par différentes raisons que l’auteur détaille, avant de souligner que l’interdisciplinarité demeure un défi ambitieux et exigeant. Discipline  : philosophie du droit
La religion de Richard Wagner, entre art et sacré
Authors: Sauvage Olivier
Published: February 2025

Les opéras de Richard Wagner, imprégnés pour la plupart de références aux mythes germaniques et scandinaves, semblent n’accorder que peu de place aux questions religieuses, si l’on excepte Parsifal . Cependant, si Wagner n’a pas composé de musique sacrée, s’il s’est engagé aux côtés des révolutionnaires de Dresde en 1849, s’il a côtoyé Bakounine et lu Ludwig Feuerbach, il ne se revendique pas pour autant athée. Nourri par la lecture du Nouveau Testament, Wagner se considérait comme un Saxon protestant, et Luther était pour lui une figure digne d’éloge, au point qu’il esquissa un opéra intitulé Les Noces de Luther . Le Christ lui inspira également un autre projet de drame. Sa lecture du Veda et d’autres textes sacrés d’Extrême-Orient l’avait en outre familiarisé avec l’hindouisme et le bouddhisme, dont il affirme l’importance primordiale vis-à-vis du christianisme. Le thème de la rédemption par l’amour, récurrent dans ses opéras, se combinera dans son ultime opéra Parsifal avec la revendication d’une Mitleid (compassion) issue de Schopenhauer, et qui doit autant au bouddhisme qu’au christianisme. La sanctification de l’art par Wagner, avec Bayreuth comme lieu de culte, constitue une autre facette originale de son esthétique. Disciplines  : littérature comparée , musicologie
Vivre l’imprévisible sans l’angoisse de l’incertitude
Authors: Furtos Jean
Published: February 2025

La crise sanitaire du COVID, et bien d’autres crises, ont ravivé l’idée de l’incertitude comme possibilité d’un effondrement de l’avenir. Il convient de distinguer l’imprévisible de l’incertitude et de voir quelles sont les conditions psychosociales, face à la précarité du monde, pour que le rapport à soi, aux autres et à l’avenir permette de vivre – c’est-à-dire de continuer à naître – et pas seulement de survivre. Par ailleurs, il est important de se souvenir que la pensée de l’ignorance acceptée a permis le développement de la science, et pas seulement des sciences dures. En témoigne, par exemple, le principe d’incertitude d’Heisenberg, applicable aux particules, mais aussi aux sciences psychosociales, par définition métissées. L’étonnement nous permet également de questionner le monde et de prendre conscience de la part de merveilleux qu’il comporte, sans ignorer toutefois que l’horreur existe aussi. C’est pourquoi il est souhaitable que la société prenne soin de ses membres afin que ceux-ci puissent faire face à l’imprévisible sans rester prisonniers de la « mauvaise précarité ». Discipline : psychiatrie, psychopathologie, clinique psycho-sociale
Faced with Disaster: the Anguish of the Experts
Authors: Levesque Alain-Nicolas , Devès Maud H.
Published: February 2025

Une littérature discrète, mais en plein essor, s’inquiète de l’épuisement mental et de l’anxiété dont témoignent les scientifiques travaillant dans le domaine du climat et de l’environnement. Le fait de savoir quelque chose des catastrophes à venir, sans avoir les moyens d’agir pour les éviter, apparaît comme un élément central de leur malaise. Mais dire cela ne dit pas grand-chose des mécanismes à l’œuvre, dans l’entrecroisement de la vie psychique aux pratiques sociales, pour transformer des chercheurs aimant chercher, en experts angoissés. Cet article propose d’approfondir l’examen en s’appuyant sur l’expérience des scientifiques spécialistes de l’observation des phénomènes naturels dangereux, confrontés de longue date à la perspective de la catastrophe. Mobilisant les méthodes de l’enquête sociologique et de l’analyse de discours, il donne à voir la manière dont différentes logiques, discours et injonctions s’entremêlent jusqu’à rendre intenable la position subjective du chercheur placé en situation d’expertise. La catastrophe, hybride et complexe par nature, le confronte aux limites de son propre savoir et, plus généralement, à celles du projet scientifique moderne.
SARS-CoV-2 et réponse immunitaire
Authors: Josien Régis , Danic Gwénaëlle , Martin Jean-Claude
Published: February 2025

Le système immunitaire joue un rôle majeur dans le contrôle de l’infection liée au SARS-CoV-2 et son dysfonctionnement est à l’origine de la plupart des complications – parfois graves – de la COVID-19. La compréhension des différents mécanismes immunitaires en jeu au cours de la maladie est donc nécessaire à la mise en place de nouvelles stratégies thérapeutiques, plus ciblées sur les dérégulations associées aux formes sévères. L’objectif de cette revue est de synthétiser les principaux évènements de la réponse immunitaire induite en réponse à l’infection par ce coronavirus émergent, en insistant sur les dysfonctionnements majeurs s’associant au développement de formes sévères et les facteurs immunopathologiques prédisposants. Le fondement immunologique des principales stratégies vaccinales actuellement disponibles est également exposé.
Digital Technologies in Education
Authors: Roy Bitan , Ghosh Sanchita , Roy Piyal , Sarkar Saptarshi Kumar , Choudhury Nobhonil Roy
Published: February 2025

This document evaluates the integration of robotics and artificial intelligence in learning and teaching practices, highlighting the potential benefits and challenges. It highlights the potential for increased STEM education, improved critical thinking skills, and increased student engagement. However, challenges include high costs, technical support, and reduced face-to-face interaction. Recommendations include applying for grants, forming partnerships, and implementing efficiency approaches. The document emphasizes the need for continuous professional development for educators to integrate these technologies into teaching. It also highlights the need for further development in blockchain, virtual/augmented reality, and AI for adaptive learning. Measures include providing student data protection laws, increasing online resources, and developing professional development programs. The document also emphasizes the need for equal learning environments and ongoing research on generation, cohort, and age differences and educational technologies.
Does Socio-Demographic Influence Digital Wallet Adoption Behavior?
Authors: Sait Muhammad Azmi , Anshari Muhammad , Almunawar Mohammad Nabil , Masri Masairol , Junit Nazatul Haziqah
Published: February 2025

Recent advancements in digital technology and widespread internet connectivity have accelerated the global adoption of digital wallet services. While existing digital wallet research has extensively identified key direct determinants to acceptance and adoption intentions, this study focuses on socio-demographic factors affecting adoption behaviors – adoption, discontinuance, and resistance intentions. Using chi-square test of association on data collected from 442 respondents in Brunei Darussalam, this study has found the significant influences of age, education, and income on adoption decisions, with gender showing no significant impact. This underscores the critical role of socio-demographic variables in refining technology adoption theories. Additionally, it highlights the need for targeted marketing strategies to enhance digital wallet acceptance and robust policy frameworks to sustain and advance the digital wallet industry in developing countries.
The Impacts of Agricultural Digital Technologies to the Youth Generations for Food Security and Rural Development
Authors: Rusliyadi Muhamad , Chen Yu Hua
Published: February 2025

This study explores the impacts of agricultural digital technologies on the youth generation in Indonesia, focusing on their contributions to food security and rural development. Utilizing a mixed-methods approach, the research combines quantitative data from surveys of young farmers with qualitative insights from interviews and focus groups. Findings reveal that digital technologies, such as precision farming, mobile apps, and e-commerce platforms, significantly enhance agricultural productivity, market access, and knowledge dissemination among the youth. These advancements are shown to increase food security by improving crop yields and reducing post-harvest losses. Additionally, the integration of digital tools in agriculture fosters rural development by creating new job opportunities, reducing urban migration, and encouraging sustainable farming practices. The research underscores the importance of supportive policies and targeted training programs to empower young farmers and ensure the sustainable development of rural areas in Indonesia.
AI-Powered Data Platforms Bridging the Gap Between Analytics and Action in Smart Education
Authors: Ranjan Rahul
Published: February 2025

This chapter explores the transformative potential of AI-powered data platforms in bridging the gap between analytics and actionable insights within smart education environments. As educational institutions increasingly adopt technology to enhance learning outcomes, the role of data analytics becomes paramount. AI-powered data platforms enable educators and administrators to harness vast amounts of data from diverse sources, transforming it into meaningful insights that inform decision-making and drive instructional improvements. This chapter discusses the core functionalities of AI-powered data platforms, including data integration, real-time analytics, predictive modeling, and personalized learning pathways. It also examines case studies demonstrating the effectiveness of these platforms in fostering data-driven cultures in educational settings. By leveraging AI-driven insights, institutions can better address student needs, improve resource allocation, and enhance overall educational experiences.
Automating AI Infrastructure
Authors: Devan Karthigayan
Published: February 2025

This chapter explores the automation of AI infrastructure within scalable and optimized cloud platforms, specifically tailored for the realm of smart education. As educational institutions increasingly leverage AI technologies to enhance learning experiences, the need for robust and efficient cloud solutions becomes paramount. This chapter delves into the critical components of automated AI infrastructure, including cloud architecture, resource management, and deployment strategies. By examining best practices for automation, scalability, and optimization, the chapter provides a comprehensive guide for educators and administrators looking to implement AI-driven solutions in their institutions. Additionally, real-world case studies illustrate the successful application of these principles in smart education settings, highlighting the transformative impact of automation on educational outcomes. The insights presented aim to equip stakeholders with the knowledge to harness AI effectively, ensuring sustainable and adaptive learning environments.
Generative AI for Creative Learning Content Creation
Authors: Attaluri Vivekchowdary , Mudunuri Lakshmi Narasimha Raju
Published: February 2025

Generative AI is revolutionizing the landscape of creative learning by empowering students, educators, and creators to generate content, enhance project-based learning, and facilitate art generation. This paper explores the integration of generative AI tools in content creation, where learners can produce text, audio, and visual content with ease, fostering creativity and personalized learning experiences. In project-based learning, AI-driven platforms provide innovative approaches for hands-on projects, allowing students to simulate real-world scenarios, problem-solving, and interdisciplinary collaboration. Furthermore, AI-generated art is reshaping the art world by enabling new forms of expression and democratizing the creative process. This study highlights the potential of generative AI to transform education through enhanced creativity, engagement, and personalized learning paths.