bluuebunny/crossref_metadata_2025 huggingface dataset:
Nghiên cứu sự biến đổi hình thái, chức năng thất phải bằng siêu âm tim trước và sau lọc máu ở bệnh nhân suy thận mạn tính giai đoạn cuối
Authors: Thế Thọ Phạm , Thái Giang Phạm , Thái Hà Trần , Văn Cường Nguyễn , Văn Chính Phạm , Thị Thu Hoài Nguyễn
Published: January 2022

Mục tiêu: Đánh giá sự biến đổi một số chỉ số kích thước, chức năng thất phải (RV) bằng siêu âm tim (SAT) trước và sau cuộc lọc máu ở bệnh nhân suy thận mạn (STM). Đối tượng và phương pháp: Nghiên cứu tiến cứu, mô tả cắt ngang; 71 bệnh nhân STM lọc máu chu kỳ (LMCK) điều trị tại Khoa Thận-Lọc máu, bệnh viện Trung ương Quân đội (TƯQĐ) 108. Đánh giá các chỉ số siêu âm RV trước và sau lọc máu bằng các kỹ thuật: Siêu âm TM, Doppler xung, Doppler mô, siêu âm đánh dấu mô 2D. Kết quả: Các chỉ số đánh giá kích thước RV trên siêu âm giảm rõ rệt sau lọc máu: Giảm RV, RVOT, EDA, ESA (p<0,01). Các chỉ số đánh giá chức năng tâm thu sau lọc: Tăng chỉ số Tei RV (0,49 ± 0,06 so với 0,39 ± 0,07, p<0,01), TAPSE, S’, RV GLS (%) và RVFW LS (%) giảm rõ rệt (p<0,01). Các chỉ số đánh giá chức năng tâm trương sau lọc: Vận tốc các sóng E, A, E’, A’, tỷ số E/A, E’/A’ giảm rõ rệt (p<0,01); tăng thời gian giảm tốc sóng E (p<0,01). Kết luận: Ở bệnh nhân bệnh thận giai đoạn cuối, các thông số hình thái và chức năng RV trên SAT bị ảnh hưởng rõ rệt bởi lọc máu.
Extrapulmonary Tuberculosis Manifests as Middle Ear Tuberculosis: A Rare Case Report from Secondary Health Care Center at Sub-Himalayan Region
Authors: Sharma Shivbrat , . Shachita , Bhardwaj Parul
Published: January 2022

Tuberculosis of ear is a rare entity. Early diagnosis and prompt treatment can prevent many serious complications. Here we report a case of 45 year old female with middle ear tuberculosis which was cured with mastoid exploration followed by anti tubercular treatment.

Keywords: Tuberculosis, TB, Extrapulmonary Tuberculosis, Middle Ear Tuberculosis, Sub-Himalayan Region
Pengembangan Aplikasi Virtual Tour (Wisata Virtual) Objek Wisata dengan Konten Image Kamera 360
Authors: Istita Seli , Suroyo Heri
Published: January 2022

Aplikasi yang berbasis website telah menjadi kebutuhan, salah satunya aplikasi web dalam bentuk virtual tour sebagai media informasi untuk meperkenalkan tempat objek wisata yang berada di kota, Penelitian ini mengambil kota lahat sebagai objek utama, dimana informasi akan di tampilkan secara visual dari suatu lokasi dengan panorama 360 sehingga pengguna dapat mengetahui objek wisata. Metode yang digunakan adalah metode Multimedia Development Life Cycle (MDLC) yang merupakan metode rancang bangun perangkat lunak multimedia yang menekankan pada 6 tahap pengembangan multimedia. Adapun Fitur yang akan digunakan adalah maps, informasi, panorama 360°, comment, like dan rating. Manfaat aplikasi virtual tour ini dapat memudahkan wisatawan untuk melihat objek wisata yang ada di kota lahat.
Pengembangan Aplikasi Pengelolaan Proses Bisnis Dengan Metode Waterfall
Authors: Abdush Shomad Bukhori  , M. Ainul Yaqin  , Syahiduz Zaman
Published: January 2022

Perkembangan teknologi informasi selaras dengan perkembangan dunia. Dunia yang sekarang dilanda pandemi harus dapat beradaptasi dengan penggunaan teknologi yang dapat membantu kebutuhan pelaku bisnis. BPMN sering digunakan tetapi seringkali tidak dapat diimplementasikan secara langsung dalam sistem informasi yang digunakan. Dalam kondisi pandemi ini banyak masalah yang bermunculan, pelaku bisnis dituntut untuk dapat beradaptasi. Salah satunya adalah beradaptasi dengan kebiasaan dari customer yang berubah atau New Normal. Masalah lain yang sangat jelas adanya adalah penurunan omset dari bisnis. Hal ini membuat pelaku bisnis harus memikirkan cara agar tetap bisa bertahan dengan kondisi tersebut. Business Proces Management System (BPMS) merupakan salah satu teknologi yang dapat mengimpelementasikan BPMN sesuai dengan model yang dibuat. Pada penelitian ini berhasil mengembangkan BPMS dengan metode Waterfall sehingga permasalahan-permasalahan tersebut dapat terselesaikan yaitu penerapan online platform yang tidak membebani keuangan karena perubahan-perubahan aplikasi dapat disesuaikan dengan proses bisnis yang diinputkan.
Perancangan Data Warehouse untuk Profiling Data Pelanggan pada Bidang Telekomunikasi
Authors: Insani Rokhmatul
Published: January 2022

Pelanggan merupakan aset terpenting pada sebuah perusahaan, termasuk pada perusahaan pada bidang telekomunikasi. Banyaknya data pelanggan dapat dimanfaatkan untuk mencari informasi lebih detail mengenai pelanggan sehingga dapat memberikan pelayanan terbaik bagi pelanggan. Profil pelanggan dapat membantu perusahaan untuk lebih memahami basis pelanggan yang dimiliki. Profil pelanggan diperlukan perusahaan untuk mengetahui karakteristik pelanggan sehingga mempermudah perusahaan melakukan pemasaran terhadap para pelanggan tersebut. Profil pelanggan dapat dilakukan dengan intelijen bisnis. Salah satu komponen intelijen bisnis adalah data warehouse. Data warehouse digunakan untuk menyimpan data secara historis yang berasal dari data transaksional. Penelitian ini menghasilkan skema data warehouse sesuai dengan kebutuhan bisnis perusahaan.
La persistance du trouble au sens de l’art. 28a al. 1 ch. 3 CC et sa preuve dans le cadre d’articles publiés sur internet
Authors: Papaux van Delden Marie-Laure
Published: January 2022

L’ATF 147 III 185 (arrêt du Tribunal fédéral 5A_247/2020 du 18 février 2021) se prononce sur différentes questions d’importance en droit civil de la protection de la personnalité (art. 28 ss CC). Les exigences quant à la réalisation de la condition de la persistance du trouble et à sa preuve dans le cadre de l’action en constatation selon l’art. 28a al. 1 ch. 3 CC sont clarifiées en présence de contenus médiatiques publiés sur internet. La relation entre la perception attendue du lecteur/lectrice moyen.ne et son impression générale en tant que critère d’appréciation d’une atteinte aux droits de la personnalité au sens de l’art. 28 al. 1 CC est mise en évidence en tenant compte des particularités des reportages des médias sur des portails en ligne. Les lignes directrices à prendre en compte pour déterminer si une personne doit tolérer la publication d’un reportage dans lequel figurent son nom et son image sont précisées. Des considérants non publiés de l’arrêt sont également d’intérêt ; ils portent sur la confirmation générale de l’imprescriptibilité des actions défensives au sens de l’art. 28a al. 1 CC, contrairement aux actions réparatrices réservées à l’art. 28a al. 3 CC, soumises à la prescription de l’art. 60 CO.
Parametric estimation of supplier's plant construction costs
Authors: Rossi Remo
Published: January 2022

Cost engineers of buying enterprises perform detailed product cost calculations of externally manufactured components. The aim of these calculations is to determine what a product should cost and to support purchasing functions in fact-based negotiations. While product cost engineers have deep knowledge in the calculation of direct cost, they need support in the calculation of supplier´s indirect cost categories. The calculation of industrial rent, which is expressed in annual cost per m² of occupied plant building floor space can be improved by providing accurate construction cost estimates. Construction costs are strongly impacting the calculation of supplier´s annual building depreciation, which is a crucial cost driver for the determination of the industrial rent. Academic literature is actually not providing an accurate and suitable cost model for product cost engineers, which is estimating construction cost per m² depending on different industrial building categories and alternative supplier plant locations. The paper aims to close this gap by applying linear regression analysis on a set of European construction cost data considering two industrial building categories: “warehouses/basic factory units” and “high-tech factories”. By regressing construction cost against construction labor rates within different supplier plant locations it was possible to form suitable and accurate parametric regression functions with R² values between 0.74 and 0.88. Next to high R² values acceptable mean average percentage errors between 7.45% and 11.77% could be realized by comparing estimated with observed construction cost.
The estimation of industrial construction costs based on the paper´s results can be used to improve the calculation of industrial rent, which is one cost element, that has to be covered within product cost engineer´s Should Cost Calculations.
FORMATION AND DEVELOPMENT OF PHARMACEUTICAL EDUCATION IN RUSSIA, BELARUS AND THE USA (THE 16TH CENTURY - THE 70’S OF THE 20TH CENTURY)
Authors: Conroy M. Sh. , Sosonkina V. F.
Published: January 2022

Formation and development of pharmaceutical education in Russia, Belarus and the USA based on the analysis of a wide range of references at different historical stages is studied. The dates of establishing first pharmacies, educational institutions and pharmacopoeia editions in the countries are indicated. Analysis and comparative characteristics of the educational process in different countries is made, its general and fundamental differences are reflected. It is noted that this process was decentralized in the US and at the same time it was centralized in continental Europe including Russia and Belarus. Classification of pharmacies in the Russian Empire in the pre-revolutionary period of 1917, obtaining by women the right to be engaged in pharmaceutical activities, are presented. Some people who had a strong influence on the development of the pharmaceutical education are listed and among them were A. Fennel, G. Eger, E. Highstreet, K. Dov, A. Lesnevskaya, A. Iovskiy, Y. Trapp, V. Tikhomirov. The role of educational institutions in improving qualifications of certified specialists is indicated. The article lists the Soviet institutions which trained pharmaceutical personnel during the Great Patriotic War.
Analisis Perbandingan Persediaan Optimum dengan Metode Lot for Lot, Period Order Quantity dan Economic Part Period
Authors: Rini Monanda Wandita , Ananda Nessa
Published: January 2022

PT. X is a company engaged in the production of electrical and electronic equipment, one of its products is camera. This research aims to compare the inventory policies that have been implemented by the company with other dynamic deterministic models. In the production process, the company uses a stock policy with the Lot for Lot (LFL) method, but the total costs incurred by the company and the frequency of ordering are still quite high. This research aims to compare the inventory policies that have been implemented by the company with other dynamic deterministic models, such as Period Order Quantity (POQ) and Economic Part Period (EPP) methods so that the optimal inventory method can be determined. The results of this study indicate that the Economic Part Period (EPP) is the optimal method with a total cost of Rp. 69,284,600 and the order frequency is 7 times.
El bilingüismo: análisis y reflexiones para docentes y estudiantes
Authors: Nina Quispe Nidia Esther , Colque Cruz Luz Estefany , Alata Chusi Job Wilson
Published: January 2022

El presente artículo de revisión tiene el objetivo de generar análisis y reflexiones sobre la importancia del bilingüismo, para docentes y estudiantes de educación. Para lograr este objetivo se ha seleccionado algunos estudios realizados, los cuales han servido de base para los análisis y reflexiones: conceptuales y teóricos, destacando los diversos conceptos, los tipos, los factores, la importancia, el proceso de adquisición y los niveles del bilingüismo. En conclusión, el bilingüismo presenta concepciones diversas, cuya importancia presenta marcas lingüísticas, culturales, biológicas, sociales, étnicas.
Nutritional Potential and Bioactive Compounds in Cereus jamacaru DC: An Multifaceted Cactus From Brazilian Semiarid
Authors: De Almeida Michelle Maylla Viana , Araújo Fernando Dos Santos , Andrade Alberício Pereira , Aquino Pedro Gregório Vieira , Valença Roberta De Lima , Bruno Riselane De Lucêna Alcantara
Published: January 2022

Cereus jamacaru DC. is an endemic cactus of the Brazilian semiarid region empirically used by humans for forage, food and medicinal purposes. In this paper, we characterize the physicochemical and phytochemical profile of the C. jamacaru cladode and fruits, outlining their nutritional implications. We evaluate the basic physicochemical characteristic of the fruits and the main classes of chemical compounds present in aqueous and ethanolic extracts from cladode, peel, and pulp of ripe and semi-ripe fruits through qualitatively and quantitatively methods. We analyze the data through descriptive statistics and variance analysis. The fruits have appropriate pH, acidity, and total soluble solid levels for the fruit processing industry and fresh consumption. We identified the presence of saponins, tannins, flavones, flavonols, and xanthones in all samples, but alkaloids and steroids were both detected in cladodes exclusively. The phenolic compound and flavonoid contents vary according to the extraction method and sample class. The cladodes and pulp of ripe fruits have the highest flavonoid levels, while the content of phenolic compounds had a high level in peels of ripe and semi-ripe fruits. The presence of these bioactive compounds implies that C. jamacaru products have relevant pharmacological interest and functionality for human (fruits) and domestic ruminant (cladodes) food. These applications can boost the agricultural-economic exploration of C. jamacaru and contribute to income generation, and improve human and animal nutrition.
Dispute over Grammatical Boundaries
Authors: بنت عبدالله السحيم رغد
Published: January 2022

This research studies the dispute among grammarians over some of the boundaries of grammatical categories by following the inductive-analytic approach. The selection of dispute issues is based on the objection by one of the dissenters with the linguistic inheritance. The disputes are classified in two sections, each of which embodies references you consult, and weighting what has been proven correct.
龔自珍戒詩歷程考論
Authors: 張日郡 張日郡
Published: January 2022

龔自珍為清代著名的詩人及思想家，而這樣一位「但開風氣不為師」的詩人，一生有過幾次自覺戒詩的經驗，而「戒詩」的現象在中國詩歌史上相當特殊的，詩人為何要戒詩，而又破戒？龔自珍內心「寫作的焦慮」之根源是什麼？本文試圖從兩個方面切入，其一、爬梳相關文獻，先行探求龔自珍的詩學觀，唯有如此，我們才能從中得知為何是戒「詩」。其二、切入相關詩歌文本，觀看龔自珍自己如何看待自己的「戒詩」與「破戒」的說法。最後，分析兩者之間的關係，以及變化。期能為龔自珍之相關研究做出一點貢獻。

 

Gong Zizhen was a famous poet and thinker in the Qing dynasty. The era he lived was a turning point from flourish to the decadence, from tradition to modern. This phenomenon can be read in the works from Gong Zizhen and it’s also the key point for emancipation of the ideas in late Qing dynasty. Gong Zizhen who leaded the fashion but not stood under the spotlight, he had many experiences of quitting writing poetry. Quitting writing poetry is a special phenomenon in the history of the Chinese poetry, why did poet want to quit? The thesis studied these from two aspects. The first is to explore the poetry concept of Gong Zizhen through article review so that it may be understood why he choose to quit writing poetry? Second, it could be discovered how did Gong Zizhen treat his explain about quitting writing poetry and breaking it repeatedly by reviewing related poetries. Last, analyzing the relationship and transformation between the two. Expecting to offer some contributions for the study of Gong Zizhen.

 
專業西班牙文翻譯課程實施自主學習之成效探討
Authors: 吳仙凰 吳仙凰
Published: January 2022

教育部《十二年國民基本教育課程綱要總綱》強調學生是自發主動的學習者，學校教育應誘發學生的學習動機與熱情，並培育學生成為具有社會適應力與應變力的終身學習者。因此，本研究旨在探討專業西班牙文翻譯課程實施自主學習之成效，並實施問卷調查，了解學生對於翻譯教學結合自主學習之看法，包括課程設計、合作方式、成績評量及學習成效等面向。研究結果指出，藉由翻轉課堂上教師與學生之角色、鬆綁教學控制與結合控制動機等方式可誘發學生的學習動機並提升翻譯能力。

 

The Curriculum Guidelines of the 12-Year Basic Education of the Ministry of Education emphasize that students should be spontaneous and motivated learners. Thus, the role of schools is to stimulate students’ learning motivation and enthusiasm in order to prepare them for future societal adaptation and obtain the ability to be a life-time learner. Thus, this study aims to analyze the effects of integrating autonomous learning into the specialized Spanish translation class. The survey findings cover the following aspects: 1) course design: curriculum planning and didactic methodology and process; 2) translation assignments: individual and team work, semester-end learning projects; 3) translation assessment; 4) learning effectiveness. According to the students’ feedback from the questionnaires, the research demonstrates that students’ learning motivations and translation competences can be fostered in autonomous learning by the following methods: changing the roles of teachers and learners in the classroom, allowing students to decide their own learning strategies, and combining controlled motivational factors to encourage students.

 
Marcadores de obesidade na avaliação do estado nutricional em adolescente
Authors: Oliveira Maria Nubia Gama
Published: January 2022

Este livro é resultado da pesquisa de doutorado em um Centro de Referência de Adolescente. O que se destaca a recomendação da leitura do livro marcadores de obesidade na avalição do estado nutricional em adolescente é o método científico, trazendo à tona, à proposta, à pesquisa científica, à faixa etária de 10 a 19 anos. Estudar e atender adolescente são desafiadores, dado que, neste segmento observa-se uma fase de mudanças biológicas importantes, o consumo de refeições nem sempre satisfatória em nutrientes como vitamina A, E e β─caroteno. Somando-se a tudo isto, o excesso de calorias corrobora a ocorrência de dislipidemia, hiperleptinemia e obesidade, acelerando o risco para a doença cardiovascular. Alguns fatores de risco da DCV têm sido associados ao estresse oxidativo, por essa razão o aporte de nutrientes antioxidantes, dentre os quais, a vitamina A (retinol e β─caroteno) e a vitamina E foram estudados como marcadores metabólicos. Variáveis clínicas e laboratoriais são instrumentos aplicados na prática e anamnese clínica, contudo o polimorfismo Q223R do gene do receptor da leptina, vitaminas antioxidantes e leptina sérica, ainda, são ferramentas não tão bem conhecidas, porém valiosas, a fim de traçar o estado nutricional em adolescente obeso. É indubitavelmente importante destacar que, a medida que esta geração de adolescente é exposta a alimentação precária em nutrientes, se aumenta a incidência e prevalência de obesidade e doenças metabólicas em adultos jovens. Concebe-se que, os resultados observados reforçam à necessária busca de diagnóstico precoce de obesidade e as comorbidades associadas. Com efeito, é relevante formular propostas de ações públicas, a fim de amenizar estes impactos negativos à saúde desta população, assim como das futuras. Por fim, espero que ao final, o leitor tenha sido instigado a querer conhecer cada vez mais sobre a saúde do adolescente. Boa leitura!
Prefácio do livro: Marcadores de obesidade na avaliação do estado nutricional em adolescente
Authors: Rosa Glorimar
Published: January 2022

Atualmente a obesidade é considerada a desordem metabólica de maior predomínio nas sociedades e um dos maiores obstáculos da saúde pública mundial e está diretamente relacionada a uma série de fatores como hábitos alimentares e atividade física, além de fatores biológicos, comportamentais, econômicos e psicológicos. A obesidade acomete indivíduos de diferentes faixas etárias, no entanto, foi evidenciado um aumento significativo em idades cada vez mais precoces, preocupando pesquisadores e profissionais da saúde, pois há uma maior probabilidade de crianças e adolescentes obesos se tornarem obesos na fase adulta. A obesidade é fortemente associada à comorbidades, como resistência à insulina, diabetes mellitus tipo 2, hipertensão arterial e dislipidemia, que aumentam consideravelmente o risco de desfechos cardiovasculares na vida adulta. A prevenção dessas principais situações de risco, desfechos patológicos, deve iniciar na infância e adolescência, uma vez que é mais difícil reverter a obesidade na idade adulta assim como tratar as doenças associadas. Há a necessidade de aprimoramento da avaliação nutricional e detecção risco cardiometabólico, a partir de novos estudos e pesquisas em busca de novos marcadores que possibilitem a detecção precoce desse risco, o que tem respaldo na complexidade das questões que envolvem o crescimento infantil e desenvolvimento na adolescência. O equilíbrio energético é regulado pelo sistema de sinalização da leptina-melanocortina, quando a leptina se liga ao seu receptor promovendo a saciedade e, assim associado esse hormônio a obesidade e suas comorbidades. Nesse contexto este livro reúne conhecimento atualizado, estimulando o leitor à reflexão sobre o aspecto molecular, reconhecendo a existência de inúmeros genes envolvidos na codificação de proteínas e metabólitos envolvidos no balanço energético e formação do tecido adiposo, destacando o polimorfismo Q223R do gene do receptor da leptina. Além da valorização da avaliação nutricional baseada em dados antropométricos e estudo dietético, o que permite a avaliação da ingestão de nutrientes antioxidantes que fazem frente ao estresse oxidativo, associado ao desenvolvimento e o agravamento das doenças cardiovasculares. Cabe ao leitor usufruir desse conteúdo de excelência para aprimorar seus conhecimentos acerca da avaliação nutricional, marcadores cardiometabólicos em adolescentes, baseado em evidências científicas. Agradeço a honra de escrever esse prefácio e deixo maior espaço para leitura deste livro, desejando a todos uma excelente leitura e aprendizado.
PAPEL DO MICRORNA-26A NO REPARO DO TECIDO RENAL EM MODELO DE LESÃO RENAL AGUDA
Authors: Gomes Pedro Paulo Gattai
Published: January 2022

O fator de crescimento dos hepatócitos (HGF) tem papel relevante no reparo tecidual. O microRNA-26a é um modulador endógeno de HGF. O papel do miR26a no processo de reparo renal foi avaliado em ratos Wistar submetidos a modelo de lesão renal aguda por rabdomiólise induzida por glicerol (6 mL / kg). Os animais foram avaliados 3, 12, 48, 96 e 120 horas após a injeção de glicerol. A creatinina sérica (SCr) e a expressão gênica de HGF, c-met, STAT3 e miR-26a foram estimados. Células NRK52E transfectadas com anti-miR26a e estimuladas com Fe3 + por 24 horas imitaram os efeitos da mioglobina in vitro. SCr foi maior após 48 horas, diminuindo após 96 horas, caracterizando a recuperação, normalizando após 120 horas. A expressão de HGF aumentou durante o início (3 horas), com baixa relação com miR-26a. Na recuperação, o aumento no miR-26a foi coincidente com a supressão do RNA mensageiro do HGF, sugerindo que nesta fase, o miR-26a pode ter um papel na modulação do HGF. O Fe3 + induziu morte celular após 3 horas e proliferação após 24 horas. Não houve correlação entre miR26a e STAT3 durante a fase de morte; Porém, durante a fase de proliferação, um aumento no STAT3 foi paralelo a uma diminuição no miR-26a. O silenciamento de miR26a induziu aumentos na viabilidade celular e a forma fosforilada da proteína STAT3 em células que receberam Fe3 +. O miR-26a pode ter um papel fundamental na modulação dos níveis de HGF após seus efeitos proliferativos terem sido desencadeados.
IDENTIFICAÇÃO DE ALTERAÇÕES NA ATIVIDADE DAS ENZIMAS HEPÁTICAS EM PACIENTES COM INFECÇÃO CRÔNICA PELOS VÍRUS DA HEPATITE B OU C POR METABONÔMICA BASEADA EM RMN DE 1 H
Authors: Santos Joelma Carvalho , Gouveia Liana Ribeiro , Batista Andrea Dória , Moura Izolda Maria Fernandes de , Godoy Michele Maria Gonçalves de
Published: January 2022

O objetivo deste estudo foi identificar alterações na atividade das enzimas hepáticas (ALT, AST e GGT) devido à infecção pelos vírus da hepatite B (HBV) ou C (HCV), em uma única amostra de soro, por meio de modelos metabonômicos baseados em espectroscopia de Ressonância Magnética Nuclear de hidrogênio (RMN de 1 H). Foram incluídos 203 pacientes adultos previamente diagnosticados com monoinfecção pelo HBV (n=117) ou HCV (n=86). Os espectros de RMN foram obtidos utilizando o espectrômetro VARIAN Unity Plus 300, enquanto os níveis de atividade enzimática por método cinético automatizado, que foram tidos como padrão-ouro. Os modelos foram construídos usando Análise Discriminante por Projeção Ortogonal de Estruturas Latentes (OPLS-DA), na plataforma MetaboAnalyst 3.6. São três modelos para avaliação da atividade enzimática, independentemente do tipo de vírus relacionado à infecção: (1) ALT; (2) AST; e (3) GGT. O modelo ALT apresentou sensibilidade (Sn) de 95,4%, especificidade (Sp) de 93,9% com maior concentração de carboidratos e menores níveis de HDL e LDL, aminoácidos e espécies insaturadas e aromáticas no grupo com ALT elevada. Acurácia semelhante foi encontrada para o modelo AST, com Sn=95,5%, Sp=96,5% e atividade elevada de AST também associada a maiores concentrações de carboidratos e menores níveis de aminoácidos. O modelo para GGT não foi discriminante. Portanto, os modelos construídos identificaram alterações nas atividades de AST e ALT e as classes de compostos associadas à discriminação, usando um único espectro de RMN de 1 H e representando mais uma aplicação da metabonômica para avaliar a doença hepática nesses pacientes.
Avanços em Computação Aplicada a Fluidodinâmica Computacional
Authors:   Marcelo Marques
Published: January 2022

O desenvolvimento contínuo da computação permite à ciência e a engenharia realizarem análises cada vez mais representativas da realidade física. Neste contexto, pela presente obra são reunidas comunicações de pesquisas científicas e tecnológicas que trazem avanços relacionados à aplicação de técnicas computacionais. O livro é dividido em duas seções: fluidodinâmica e computação aplicada. Por meio do primeiro capítulo são demonstrados os campos simulados de energia das ondas no reservatório da usina hidrelétrica de Tucuruí, uma das maiores do mundo em potência instalada. As simulações demonstram, por meio de 64 mapas de simulação, avanços na determinação, quantificação e representação de campos de energia de ondas para quatro condições de campos de vento soprando em dezesseis direções. No segundo capítulo é verificada a aplicação de simulação computacional na obtenção da distribuição espacial das alturas de ondas geradas pela ação de ventos severos sobre o reservatório da barragem de Jurumirim. Os avanços são evidenciados pela aplicação da técnica de modelagem paramétrica bidimensional (MPB) demonstrando o mapeamento dos campos de ondas neste que se constitui em um dos mais importantes reservatórios do sudeste do Brasil. Pelo terceiro capítulo foi realizada a análise de três importantes métodos de determinação do fetch com uma importante contribuição original, a comparação dos resultados no espaço bidimensional. O estudo é aplicado ao reservatório de San Roque, a principal fonte de água para a cidade de Córdoba, a segunda maior cidade da Argentina. O estudo permitiu afirmar que a localização do maior fetch não é condicionada pelo método adotado, como se pensava antes do estudo. No quarto capítulo foram apresentadas análises de dimensionamento de canais de navegação relacionadas ao raio de curvatura e ângulo de deriva. Os avanços atingidos pelo estudo foram motivados pela importância da movimentação de commodities agrícolas na região amazônica, sob critérios de segurança da navegação e economicidade. Por meio do quinto capítulo foi realizada uma pesquisa aplicada abordado um dos grandes desafios ambientais da atualidade, que é a utilização sustentável dos sistemas aquáticos. Foram avaliadas as concentrações de fósforo e nitrogênio nos sedimentos nas épocas seca e chuvosa e os parâmetros de adsorção de fósforo em importante rio estado do Piauí, demostrando que o período seco durante a amostragem e consequente baixa capacidade de diluição do rio contribuíram para o aumento nas concentrações de fósforo e nitrogênio total em sedimentos no corpo hídrico. No sexto capítulo foi realizada uma abordagem abrangente contemplando os estágios da semantificação de dados, desde a coleta até a publicação na Web, possibilitando a adição de significado aos dados de forma a serem compreendidos, tanto por máquinas como por pessoas. O estudo é aplicado às rotas urbanas de linhas de ônibus e, por ser escalável, demonstra potencial de extrapolação para outras localidades.
Imaging Findings of Knee Trauma on Magnetic Resonance Imaging
Authors: Ohri Poonam , Goya Shreeji , C Niveditha , Kohli Manasi
Published: January 2022

Background: Knee is one of the major joints involved in kinesis. With increasing involvement in sports related activities especially in young people, Trauma related knee pathologies have increased. An accurate diagnosis regarding the type and extent of injuries is essential for early operative as well as non-operative treatment. Methods:This prospective study included total of 82 cases. The patients were referred to the department of Radiodiagnosis from indoor and outdoor departments of Guru Nanak Dev Hospital, Amritsar with suspicion of internal derangement of the knee and with history of knee trauma.Results:The most common age group involved was young males between 15-34 years. In all age groups most of the patients were males. Most common ligament to be injured was Anterior Cruciate Ligament (ACL). Partial tears were more common than complete tears. Posterior Cruciate Ligament (PCL) tears were less common. Medial Collateral Ligament (MCL) tears outnumbered Lateral Collateral Ligament (LCL) tears and grade 2 tears were more common in both. Among the meniscal injuries Medial Meniscus (MM) tears were more common than LM and grade 3 signal was more common in both. Most of the patellar retinaculum injuries were associated with Anterior Cruciate Ligament ACL tears.Conclusions:Post-traumatic pre-arthroscopic MR imaging evaluation has proved to be cost-effective. MRI is an accurate imaging modality complementing the clinical evaluation and providing a global intra-articular and extra-articular assessment of the knee.
Updated review on venomous snakebites, therapeutic uses and future prospects of Indian traditional medicine
Authors: Joseph Nesarajan , Durairaj Sathishkumar , Gowthaman Oviya , Ganesan Vinoth Kumar
Published: January 2022

Herbal medicines can make therapeutic drugs and are an essential part of the worldwide healthcare system. Plants have always been an essential part of many indigenous peoples' life. Snakebite is a typical tropical condition that goes unnoticed. Snakebite is still a significant public health issue in many parts of the world, particularly in India, where the disease is particularly prevalent. Morbidity and mortality rates among rural and indigenous populations in the country are among the highest in the world. The problem is made worse by people delaying or refusing to seek medical care because they believe in traditional healers. People worldwide use plants to treat poisonous snakebites as folk medicine. Five hundred twenty-three plant species belonging to the 122 families are recognized as a source of drugs/compounds recognized as a possible cure for snakebite. However, this assessment is limited to a small number of essential plants used in snakebite poisoning in India. The most important groups from which various plants are employed include Acanthaceae, Amaranthaceae, Apocynaceae, Cucurbitaceae, Euphorbiaceae, and Fab Lamiaceae and Moraceae. In this investigation, phytocompounds with anti-venom action were discovered in 29 plants belonging to 22 families used as a traditional medicine to treat poisonous snakebites.
The Role of Internet Use on Individual Income: East Java Rural Case Study
Authors: M. Fahmi Priyatna  , Sonia Anggun Andini
Published: January 2022

This study analyzes the role of internet utilization on individual income in rural areas of East Java and Peer Provinces (West Java and Central Java) using 2018 Sakernas data. This study uses propensity score matching (PSM) and a probit model to achieve the research objectives. The estimation results show that theprobability of using the internet in East Java is affected by individual age, working experience, formal and informal education, migration, financial management, and agricultural business. Furthermore, this study found that internet usage by individuals in rural areas of East Java Province has increased individual income.There is a difference in income between individuals using the internet and not using the internet, amounting to Rp263,400. When compared with Peer Province, the difference is still below Central Java and West Java, which respectively amounted to Rp323,325 and Rp283,357.
Network Load Effects on Wireless Sensor Network Node Activity
Authors: CAN Zuhal , DEĞİRMENCİ Elif
Published: January 2022

Due to the failure-prone and vulnerable structure of WSN nodes, understanding the typical activity patterns of nodes helps to identify the faulty and malicious node activities, and to differentiate normal node behaviors from abnormal node behaviors. In this study, for understanding the typical node activities, we observe the effects of the network load on energy consumption, packet throughput, and latency parameters. We run simulations of networks with a variable number of sinks. We found that an increase in the number of sinks affects the overall network load and causes communication delays between the source and sink node.
ՆԵՐՀԱՄԱԿԱՐԳԱՅԻՆ ՀԱՐԱԲԵՐՈՒԹՅՈՒՆՆԵՐԻ ՏԵՍԱԿՆԵՐԸ ՀԱՅԵՐԵՆԻ ԵՎ ԱՆԳԼԵՐԵՆԻ «ՏԱՐԻՔ» ԻՄԱՍՏԱՅԻՆ ԴԱՇՏՈՒՄ/TYPES OF SEMANTIC RELATIONS IN THE SEMANTIC FIELD "AGE" (ON THE MATERIAL OF ARMENIAN AND ENGLISH LANGUAGES)/ТИПЫ СЕМАНТИЧЕСКИХ ОТНОШЕНИЙ В СЕМАНТИЧЕСКОМ ПОЛЕ "ВОЗРАСТ” (НА МАТЕРИАЛЕ АРМЯНСКОГО И АНГЛИЙСКОГО ЯЗЫКОВ)
Authors: Adamyan Mariam
Published: January 2022

The concept of "age" has always been studied in line with a human being, notwithstanding the fact that this feature is typical of any creature in the planet. The subject of the study is the semantic field "age" in Armenian and English languages. The characteristics of the semantic field are being discussed in the article. Particular attention is paid to the types of the semantic relations, since the units of the semantic field are connected by systemic semantic relations.
LEGAL COMPARISON OF FREEDOM OF EXPRESSION AND FREEDOM OF THE PRESS
IN THE REPUBLIC OF ARMENIA AND IN THE REPUBLIC OF POLAND/ՀԱՅԱՍՏԱՆԻ ԵՎ ԼԵՀԱՍՏԱՆԻ ՀԱՆՐԱՊԵՏՈՒԹՅՈՒՆՆԵՐՈՒՄ ԿԱՐԾԻՔԻ ԱՐՏԱՀԱՅՏՄԱՆ ԵՎ ՄԱՄՈՒԼԻ ԱԶԱՏՈՒԹՅԱՆ ԻՐԱՎԱՀԱՄԵՄԱՏԱԿԱՆ ՎԵՐԼՈՒԾՈՒԹՅՈՒՆԸ/СРАВНИТЕЛЬНО-ПРАВОВОЙ АНАЛИЗ СВОБОДЫ ВЫРАЖЕНИЯ МНЕНИЯ И СВОБОДЫ ПЕЧАТИ В РЕСПУБЛИКЕ АРМЕНИЯ И В РЕСПУБЛИКЕ ПОЛЬША
Authors: Lis Wojciech
Published: January 2022

Freedom of expression and freedom of the press form guarantee and emphasize the democratic character of a state. The dissemination of information and opinions is a prerequisite of democracy, which essentially requires that citizens be guaranteed the possibility to participate in public affairs. An opportunity to learn some information and opinions is of paramount importance for broadening knowledge, sharpening the critical mind, shaping one’s own views and making rational and informed choices. For full access to information and opinions circulating in the public, it is necessary that it should be made public and media and their journalists will make it in the best way.
ENDURING RIVALRY AND CONFLICT TRANSFORMATION: THE CASE OF NAGORNO-KARABAKH/ՁԳՁԳՎՈՂ ՀԱԿԱՄԱՐՏՈՒԹՅՈՒՆ ԵՎ ՀԱԿԱՄԱՐՏՈՒԹՅՈՒՆՆԵՐԻ ՓՈԽԱԿԵՐՊՈՒՄ. ԼԵՌՆԱՅԻՆ ՂԱՐԱԲԱՂԻ ԴԵՊՔԻ ՇՈՒՐՋ/ДЛИТЕЛЬНОЕ СОПЕРНИЧЕСТВО И ТРАНСФОРМАЦИЯ КОНФЛИКТА: СЛУЧАЙ НАГОРНОГО КАРАБАХА
Authors: Sukiasyan Narek
Published: January 2022

This study examines the nature of the Nagorno-Karabakh conflict and tries to identify a sustainable conflict resolution path drawing on the literature and the analytical framework provided by Enduring Rivalry (ER) theory and conflict transformation scholarship, thus adding the state-society dimension of the issue. Considering the attitudes of the conflicting societies, this study argues that, even in the unlikely scenario of the consensual agreement the result will be fiercely challenged by one or all publics, not only undermining the possibility of its implementation but also regime endurance. The study suggests to consider an approach based on conflict transformation and comes up with a recommendation entailing the management of the Sarsang reservoir.
Energy planning with renewable energy sources
Authors: Narváez Félix Antonio Solórzano , Castro Edgar Iván Moreno
Published: January 2022

The urban energy model is based on imports from external sources. The continuous increase in energy demand due to population growth and development implies increasing resource requirements. The alternative is to use renewable energies that take advantage of urban resources. The diversity of typologies of cities in terms of resources, demands, architectural conditions, infrastructure, or density, makes a specific analysis necessary. This work identifies fourteen factors concerning the planning process that would allow choosing the most appropriate technology for a given city. Through consultation of experts, the existence of the resource is defined as the most prevalent factor, followed by economic conditions; On the other hand, it is detected that environmental aspects such as global warming, eutrophication, or acidification, are the least incidents when selecting technologies.
COMPARATIVE ANALYSIS OF THE US IMPORTATION SEASONALITY OF WOODEN MOLDINGS MADE OUT OF BRAZILIAN AND CHILEAN CONIFERS
Authors: Valerius Jaqueline , Da Silva João Carlos Garzel Leodoro , Timofiecsyk Júnior Romano , Steiner Neto Pedro José
Published: January 2022

Conifer wood moldings are classified as high value-added wood products and are used for several purposes in civil construction. Brazil is the world’s leading exporter of this product and the United States are its main destination market. It is very important to analyze the behavior of such importations and exportations to set strategies to obtain or increase the competitive advantage and improve the commercialization of these products. The objective of this study was to analyze the US importation seasonality of conifer wood moldings from Brazil and Chile, the main competitor of the Brazilian product in the US market. To write this paper, monthly data of the quantity of US importations of Brazilian and Chilean moldings from the period of 2011 to 2017 were collected from the database of the United States Department of Agriculture/Foreign Agricultural Service. The methodology proposed by Hoffman (2006) was employed to calculate the seasonal and seasonality indexes. The results indicated that the US importation of conifer wood moldings, both from Brazil and Chile, have a seasonal behavior, with great variation of the seasonal index.
ОБУЧЕНИЕ МЕДИЦИНСКОМУ АНГЛИЙСКОМУ ЯЗЫКУ С ПРИМЕНЕНИЕМ АУТЕНТИЧНЫХ АУДИОМАТЕРИАЛОВ / TEACHING MEDICAL ENGLISH WITH THE APPLICATION OF AUDIO AUTHENTIC MATERIALS
Authors: Arzumanyan Liana
Published: January 2022

Статья посвящена специфике обучения аудированию медицинского английского языка в высших неязыковых учебных заведениях. Рассмотрены основные и специфические навыки и умения, которые необходимы специалисту для восприятия профессионально-значимых аудиотекстов, вопросы выбора учебного материала, проблемы, с которыми сталкиваются студенты, а также задачи, отвечающие требованиям аудитории. В статье предлагаются некоторые идеи, как улучшить развитие навыков слушания и расширить знания английского языка в медицинской сфере. Раскрыта также роль техники слушания в формировании иноязычной коммуникативной компетенции у студентов в неязыковых вузах. / The article is devoted to the specificity of teaching listening comprehension of medical English in higher non-linguistic institutions. The basic and specific skills and abilities that are necessary for a specialist in the perception of professionally significant audio texts, the questions of educational material selection, the problems faced by the learners, as well as the tasks that meet the requirements of the audience are considered. The article suggests some ideas how to improve the development of listening skills and extend the knowledge of English in the medical field. The role of listening technique in forming foreign language communicative competence of nonlinguistic training directions of students is revealed as well.
Peran Program Kegiatan Karya Tulis Ilmiah Untuk Meningkatkan Daya Kemampuan Berpikir Siswa MA Raudlotul Huffadz
Authors: Ismail Syarof Nursyah
Published: January 2022

Menulis merupakan proses kreatif untuk menuangkan gagasan dalam bentuk bahasa tulis. Oleh karena itu, siswa dituntut memiliki keterampilan untuk menuangkan ide dan gagasan dengan menulis. Dengan menulis ini, diharapkan siswa mempunyai rasa keingintahuan yang tinggi serta kemampuan berpikikir yang luwes. Dan diharapkan dapat mengamati, menanya, menalar, mencoba, dan mencipta yang dituangkan dalam tulisan yang sering disebut karya tulis ilmiah. Penelitian ini bertujuan untuk mengetahui peran program kegiatan karya tulis ilmiah untuk meningkatkan daya kemampuan berpikir siswa di MA Raudlotul Huffadz, untuk mengetahui cara menjalankan program kegiatan karya tulis ilmiah di MA Raudlotul Huffadz, dan untuk mengetahui kendala yang dihadapi madrasah dalam melaksanakan program kegiatan karya tulis ilmiah. Subjek dalam penelitian ini adalah seluruh siswa-siswi kelas X dan XI di MA Raudlotul Huffadz, Tabanan tahun pelajaran 2017/2018. Metode yang digunakan untuk mengumpulkan data dalam penelitian ini adalah metode dokumen, metode wawancara, dan metode observasi. Hasil dari karya tulis ilmiah menunjukkan bahwa: (1) Peran program kegiatan karya tulis ilmiah untuk meningkatkan daya kemampuan berpikir siswa di MA Raudlotul Huffadz seperti untuk meningkatkan keterampilan membaca, untuk mengkoordinasikan gagasan, untuk mengembangkan kemampuan (skill) dan budaya menulis, sebagai salah satu syarat untuk mengikuti Penilaian Akhir Semester, untuk mempersiapkan siswa berkompetisi dalam Lomba Karya Tulis Ilmiah, dan Hasil Karya Tulis Ilmiah (KTI) terbaik siswa menjadi koleksi perpustakaan; (2) Cara menjalankan program kegiatan karya tulis ilmiah pada tahun 2016 dan 2017 untuk kegiatan karya tulis ilmiah masih berkelompok. Guru yang memang ahli dalam bidang karya tulis ilmiah tersebut yang diamanahkan untuk membimbing siswa-siswi MA Raudlotul Huffadz. Pada tahun 2018 program kegiatan karya tulis ilmiah ini wajib diikuti oleh seluruh siswa-siswi MA Raudlotul Huffadz kecuali kelas XII; dan (3) Kendala yang dihadapi dalam penulisan Karya Tulis Ilmiah diantaranya siswa-siswi MA Raudlotul Huffadz adalah santri dan santriwati di Pondok Pesantren Al-Qur’an Raudlotul Huffadz, siswa-siswi MA Raudlotul Huffadz tidak dapat mengakses internet dan membawa peralatan elektronik, ada beberapa siswa yang malas untuk membaca refensi di perpustakaan serta menulis. Serta ada siswa yang malas untuk bimbingan kepada guru pembimbingnya, masih ada sebagian besar siswa yang belum bisa mengkoordinasikan gagasan, guru dan siswa biasa menunda pekerjaan di dalam pelaksanaan kegiatan karya tulisnya.
YARGITAY 17. HUKUK DAİRESİNİN SİGORTA ETTİRENİN RİZİKONUN GERÇEKLEŞMESİNDEKİ KUSURUNUN ETKİSİNE DAİR E. 2016/646 K. 2016/1427 SAYILI KARARININ İNCELENMESİ
Authors: EMİRALİOĞLU Furkan
Published: January 2022

Sigorta ettirenin sigortacıyla sigorta sözleşmesi yapmasındaki temel amacı, sigortalanan menfaatte sözleşmeyle güvence altına alınan bir rizikonun gerçekleşmesi ve bu rizikonun sonucunda da zararın ortaya çıkması halinde bu zararların sigortacı tarafından giderilmesinin sağlanmasıdır. Sigorta ettiren, sigorta sözleşmesinde belirlenen primi ödeyerek rizikoyu taşımayı sigortacıya yüklemekte ve riziko gerçekleştiğinde meydana gelebilecek zararlara karşı da tam himaye beklemektedir. Ancak, sigorta himayesinden eksiksiz biçimde faydalanmak her zaman mümkün olmamaktadır. Sigortacı ile sigorta ettiren arasında kurulan sigorta ilişkisinin dolaylı yoldan tüm sigorta sistemini, milyonlarca kişiyi ve ülke ekonomisini etkilemesi sebebiyle kanun koyucu sigorta himayesinden eksiksiz bir biçimde faydalanılabilmesi ve sigorta kurumunun kötüye kullanılmaması adına birtakım düzenlemeler getirmiştir. Kanun koyucu “Rizikonun Gerçekleşmesinde Kusur” başlığı ile sigortanın hangi durumlarda koruma sağladığına ilişkin çerçeve bir düzenleme kaleme almış ve sigorta ettirene de sözleşmenin kurulmasından başlayarak rizikonun gerçekleşmesinden sonraki safhayı da kapsayacak şekilde birtakım külfetler yüklemiştir. Bu çalışmada incelenen Yargıtay kararı, sigorta ettirene yüklenen bazı külfetler ve rizikonun gerçekleşmesinde kusur konuları kapsamında eleştirilmiştir.
TÜRK HUKUKUNDA KARŞILIKSIZ ÇEK KEŞİDE ETMEK FİİLİNE ÖNGÖRÜLEN YAPTIRIMLARIN TARİHSEL GELİŞİMİ VE SORUNLARI
Authors: ERŞAN Safa
Published: January 2022

Bir kambiyo senedi olan çek, tedavül kabiliyeti ve yaygın kullanımı sebebiyle diğer kambiyo senetlerinden ayrı bir öneme sahiptir. Çekin karşılıksız çıkması durumunda uygulanacak yaptırımın ne olacağı konusu Türk hukukunda öteden beri tartışmalı bir alan olarak yerini korumaktadır.

Karşılıksız çek keşide etmek fiiline ilişkin ayrı düzenlemenin yapıldığı ilk tarih olan 1985 yılından bugüne kadar altı farklı düzenleme yapılmıştır. Bu süreç içinde Avrupa İnsan Hakları Sözleşmesi Ek 4 Numaralı Protokolün 1. maddesinde yer alan ‘‘borç için kimsenin özgürlüğünden yoksun bırakılamayacağı’’ hükmü tartışmaları başka bir boyuta taşımıştır. İç hukukumuzda yapılan yeni düzenlemeler de sorunu çözememiş ve tartışmaları nihayete erdirememiştir. 1985 yılında hürriyeti bağlayıcı bir cezayla başlayan yaptırım süreci, 2016 yılında Çek Kanunu’nda yapılan son düzenlemelerle adli para cezası yaptırımıyla sonlandırılmıştır.

Bu çalışmada çekin karşılığının bulunmaması durumunda Türk hukukunda öngörülen yaptırımların tarihsel süreç içerisindeki gelişimi; değişikliklerin gerçekleştiği dönemlerde doktrinde olan tartışmalar ile yargı kararlarına da yer verilerek incelenmiş ve görüşlerimize yer verilmiştir.
The Quality of Drinking Water for Cattle; It’s A Pity Cows aren’t Capable to Complain Verbally
Authors: Vermunt Jos J
Published: January 2022

The necessity of water for support of life is largely unquestioned. Of all the nutrients indispensable for life, water is second only to oxygen in importance. However, this commonplace fact is often not well appreciated. From a nutritional point of view, water is the most critical nutrient for dairy cattle, and is required for numerous important physiological functions. As a whole, the water content of the animal body ranges from 55 to 67 % of body weight. Water is the main component of milk, saliva, and waste products, such as urine and faeces [1]. Water is further lost from the lungs during breathing or panting, by evaporation from the skin, and sweating. Hence, dairy cattle have a large daily requirement for water, most of it being obtained from free water intake. Because dairy cattle suffer more quickly from an inadequate water intake than from a deficiency of any other nutrient, clean, fresh drinking water should be available at all times.
VMO-Teichmüller space on the real line
Authors: Shen Yuliang
Published: January 2022

An increasing homeomorphism \(h\) on the real line \(\mathbb{R}\) is said to be strongly symmetric if it can be extended to a quasiconformal homeomorphism of the upper half plane \(\mathbb{U}\) onto itself whose Beltrami coefficient \(\mu\) induces a vanishing Carleson measure \(|\mu(z)|^2/y\,dx\,dy\) on \(\mathbb{U}\). We will deal with the class of strongly symmetric homeomorphisms on the real line and its Teichmüller space, which we call the VMO-Teichmüller space. In particular, we will show that if \(h\) is strongly symmetric on the real line, then it is strongly quasisymmetric such that \(\log h'\) is a VMO function. This improves some classical results of Carleson (1967) and Anderson-Becker-Lesley (1988) on the problem about the local absolute continuity of a quasisymmetric homeomorphism in terms of the Beltrami coefficient of a quasiconformal extension. We will also discuss various models of the VMO-Teichmüller space and endow it with a complex Banach manifold structure via the standard Bers embedding.
Geodesic spaces of low Nagata dimension
Authors: Jørgensen Martina , Lang Urs
Published: January 2022

We show that every geodesic metric space admitting an injective continuous map into the plane as well as every planar graph has Nagata dimension at most two, hence asymptotic dimension at most two. This relies on and answers a question in a recent work by Fujiwara and Papasoglu. We conclude that all three-dimensional Hadamard manifolds have Nagata dimension three. As a consequence, all such manifolds are absolute Lipschitz retracts.