bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 11-18 from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin
Authors: Wagner Jessica , Wickman Elizabeth , Shaw Timothy I. , Anido Alejandro Allo , Langfitt Deanna , Zhang Jinghui , Porter Shaina N. , Pruett-Miller Shondra M. , Tillman Heather , Krenciute Giedre , Gottschalk Stephen
Published: April 2023

Supplementary Figures 11-18
Supplementary Data from Anti-VEGF Treatment Enhances CD8+ T-cell Antitumor Activity by Amplifying Hypoxia
Authors: de Almeida Patricia E. , Mak Judy , Hernandez Genevive , Jesudason Rajiv , Herault Aurelie , Javinal Vincent , Borneo Jovencio , Kim Jeong M. , Walsh Kevin B.
Published: April 2023

Supplementary tables 1-4 and supplementary figures 1-8.
Supplementary Data from IgA-Mediated Killing of Tumor Cells by Neutrophils Is Enhanced by CD47–SIRPα Checkpoint Inhibition
Authors: Treffers Louise W. , ten Broeke Toine , Rösner Thies , Jansen J.H. Marco , van Houdt Michel , Kahle Steffen , Schornagel Karin , Verkuijlen Paul J.J.H. , Prins Jan M. , Franke Katka , Kuijpers Taco W. , van den Berg Timo K. , Valerius Thomas , Leusen Jeanette H.W. , Matlung Hanke L.
Published: April 2023

Supplementary Materials and Methods
Table S6 from Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)
Authors: Huetter Julia , Gritzan Uwe , Gutcher Ilona , Doecke Wolf-Dietrich , Luetke-Eversloh Merlin V. , Golfier Sven , Roider Helge G. , Frisk Anna-Lena , Hunter John , Pow Andrew , Drake Andrew , Levine Zurit , Levy Ofer , Azulay Meir , Barbiro Inbal , Cojocaru Gady , Vaknin Ilan , Kreft Bertolt , Roese Lars
Published: April 2023

Antitumor efficacy of BAY1905254 and antiâ€"PD-L1 in monotherapy or in combination in a panel of syngeneic mouse models shown as T/C values.
Table S1 from Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)
Authors: Huetter Julia , Gritzan Uwe , Gutcher Ilona , Doecke Wolf-Dietrich , Luetke-Eversloh Merlin V. , Golfier Sven , Roider Helge G. , Frisk Anna-Lena , Hunter John , Pow Andrew , Drake Andrew , Levine Zurit , Levy Ofer , Azulay Meir , Barbiro Inbal , Cojocaru Gady , Vaknin Ilan , Kreft Bertolt , Roese Lars
Published: April 2023

Amount of ILDR2 peptides
Figures S1-S8 from Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)
Authors: Huetter Julia , Gritzan Uwe , Gutcher Ilona , Doecke Wolf-Dietrich , Luetke-Eversloh Merlin V. , Golfier Sven , Roider Helge G. , Frisk Anna-Lena , Hunter John , Pow Andrew , Drake Andrew , Levine Zurit , Levy Ofer , Azulay Meir , Barbiro Inbal , Cojocaru Gady , Vaknin Ilan , Kreft Bertolt , Roese Lars
Published: April 2023

Supplementary figures
Supplementary Figure and Table Legends from Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells
Authors: Drijvers Jefte M. , Gillis Jacob E. , Muijlwijk Tara , Nguyen Thao H. , Gaudiano Emily F. , Harris Isaac S. , LaFleur Martin W. , Ringel Alison E. , Yao Cong-Hui , Kurmi Kiran , Juneja Vikram R. , Trombley Justin D. , Haigis Marcia C. , Sharpe Arlene H.
Published: April 2023

Supplementary Figure and Table Legends
Supplementary Figures and Tables from Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection
Authors: Yuan Xiang , Liu Yiwen , Li Guifang , Lan Zijun , Ma Mingyang , Li Huaxu , Kong Jinyu , Sun Jiangtao , Hou Gaochao , Hou Xurong , Ma Yingjian , Ren Feng , Zhou Fuyou , Gao Shegan
Published: April 2023

Supplementary figures and tables.
Supplementary Data File 1 from Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells
Authors: Drijvers Jefte M. , Gillis Jacob E. , Muijlwijk Tara , Nguyen Thao H. , Gaudiano Emily F. , Harris Isaac S. , LaFleur Martin W. , Ringel Alison E. , Yao Cong-Hui , Kurmi Kiran , Juneja Vikram R. , Trombley Justin D. , Haigis Marcia C. , Sharpe Arlene H.
Published: April 2023

All dose-response curves. Dose-response curves for all library compounds
Supplementary Tables S2 and S3 from The Ratio of Exhausted to Resident Infiltrating Lymphocytes Is Prognostic for Colorectal Cancer Patient Outcome
Authors: Foroutan Momeneh , Molania Ramyar , Pfefferle Aline , Behrenbruch Corina , Scheer Sebastian , Kallies Axel , Speed Terence P. , Cursons Joseph , Huntington Nicholas D.
Published: April 2023

Table S2 is the list of studies identifying genes associated with Exh/Res programs. Table S3 is a list of signatures used for scoring tumour data and performing survival analysis
Supplementary Data Figure S1 from Quantification of Early-Stage Myeloid-Derived Suppressor Cells in Cancer Requires Excluding Basophils
Authors: Khan ANM Nazmul H. , Emmons Tiffany R. , Wong Jerry T. , Alqassim Emad , Singel Kelly L. , Mark Jaron , Smith Brandon E. , Tario Joseph D. , Eng Kevin H. , Moysich Kirsten B. , Odunsi Kunle , Abrams Scott I. , Segal Brahm H.
Published: April 2023

CD33+CD11b+CD14-CD15- fraction of OC ascites cells contains variable proportions of HLA-DR+CD123mid dendritic cells.
Supplementary Figures and Tables from Dual Relief of T-lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies
Authors: Balança Camille-Charlotte , Scarlata Clara-Maria , Michelas Marie , Devaud Christel , Sarradin Victor , Franchet Camille , Martinez Gomez Carlos , Gomez-Roca Carlos , Tosolini Marie , Heaugwane Diana , Lauzéral-Vizcaino Françoise , Mir-Mesnier Lucile , Féliu Virginie , Valle Carine , Pont Frédéric , Ferron Gwénaël , Gladieff Laurence , Motton Stéphanie , Tanguy Le Gac Yann , Dupret-Bories Agnès , Sarini Jérôme , Vairel Benjamin , Illac Claire , Siegfried-Vergnon Aurore , Mery Eliane , Fournié Jean-Jacques , Vergez Sébastien , Delord Jean-Pierre , Rochaix Philippe , Martinez Alejandra , Ayyoub Maha
Published: April 2023

Supplementary Figures S1-S10 and Tables S1-S3
Supplemental Figures S1-S9 from Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy
Authors: Kuehm Lindsey M. , Khojandi Niloufar , Piening Alexander , Klevorn Lauryn E. , Geraud Simone C. , McLaughlin Nicole R. , Griffett Kristine , Burris Thomas P. , Pyles Kelly D. , Nelson Afton M. , Preuss Mary L. , Bockerstett Kevin A. , Donlin Maureen J. , McCommis Kyle S. , DiPaolo Richard J. , Teague Ryan M.
Published: April 2023

Supplemental Figs S1-S9
Supplementary Figure S7 from TGFβ Programs Central Memory Differentiation in Ex Vivo–Stimulated Human T Cells
Authors: Dahmani Amina , Janelle Valérie , Carli Cédric , Richaud Manon , Lamarche Caroline , Khalili Myriam , Goupil Mathieu , Bezverbnaya Ksenia , Bramson Jonathan L. , Delisle Jean-Sébastien
Published: April 2023

In vivo bioluminescence, dorsal views
Supplementary Figure S5 from TGFβ Programs Central Memory Differentiation in Ex Vivo–Stimulated Human T Cells
Authors: Dahmani Amina , Janelle Valérie , Carli Cédric , Richaud Manon , Lamarche Caroline , Khalili Myriam , Goupil Mathieu , Bezverbnaya Ksenia , Bramson Jonathan L. , Delisle Jean-Sébastien
Published: April 2023

TGF-b and other cytokines
Supplementary Tables from Genetic Ablation of HLA Class I, Class II, and the T-cell Receptor Enables Allogeneic T Cells to Be Used for Adoptive T-cell Therapy
Authors: Kagoya Yuki , Guo Tingxi , Yeung Brian , Saso Kayoko , Anczurowski Mark , Wang Chung-Hsi , Murata Kenji , Sugata Kenji , Saijo Hiroshi , Matsunaga Yukiko , Ohashi Yota , Butler Marcus O. , Hirano Naoto
Published: April 2023

Tables S1-S2
Supplemental Table S1 from Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer
Authors: Kvorjak Michael , Ahmed Yasmine , Miller Michelle L. , Sriram Raahul , Coronnello Claudia , Hashash Jana G. , Hartman Douglas J. , Telmer Cheryl A. , Miskov-Zivanov Natasa , Finn Olivera J. , Cascio Sandra
Published: April 2023

Update rules and references for computational model variables.
Supplemental Fig. S3 from Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer
Authors: Kvorjak Michael , Ahmed Yasmine , Miller Michelle L. , Sriram Raahul , Coronnello Claudia , Hashash Jana G. , Hartman Douglas J. , Telmer Cheryl A. , Miskov-Zivanov Natasa , Finn Olivera J. , Cascio Sandra
Published: April 2023

IL-13 and CCL17 induce ST6GALNAC1 and sTn expression in SW480 colon cancer cells
Supplementary Table and Figures from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells
Authors: Lim Ji-Young , Kim Tae-Woo , Ryu Da-Bin , Park Sung-Soo , Lee Sung-Eun , Kim Byung-Soo , Min Chang-Ki
Published: April 2023

File includes Supplementary Table S1 and Supplementary Figures S1-S7
Supplementary Table 1 from Targeted Deletion of CXCR2 in Myeloid Cells Alters the Tumor Immune Environment to Improve Antitumor Immunity
Authors: Yang Jinming , Yan Chi , Vilgelm Anna E. , Chen Sheau-Chiann , Ayers Gregory D. , Johnson Christopher A. , Richmond Ann
Published: April 2023

Supplementary Table 1
Supplementary Figure Legends from Targeted Deletion of CXCR2 in Myeloid Cells Alters the Tumor Immune Environment to Improve Antitumor Immunity
Authors: Yang Jinming , Yan Chi , Vilgelm Anna E. , Chen Sheau-Chiann , Ayers Gregory D. , Johnson Christopher A. , Richmond Ann
Published: April 2023

Supplementary Figure Legends
Figure S5 from γδ T Cells Support Antigen-Specific αβ T cell–Mediated Antitumor Responses during BCG Treatment for Bladder Cancer
Authors: Ji Niannian , Mukherjee Neelam , Shu Zhen-Ju , Reyes Ryan M. , Meeks Joshua J. , McConkey David J. , Gelfond Jonathan A. , Curiel Tyler J. , Svatek Robert S.
Published: April 2023

Figure S5 - Figure.S5 shows that rapamycin promotes BCG treatment efficacy in mouse bladder cancer in vivo model.
Supplementary Data from Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells
Authors: Somasundaram Ashwin , Cillo Anthony R. , Lampenfeld Caleb , Workman Creg J. , Kunning Sheryl , Oliveri Lauren , Velez Maria , Joyce Sonali , Calderon Michael , Dadey Rebekah , Rajasundaram Dhivyaa , Normolle Daniel P. , Watkins Simon C. , Herman James G. , Kirkwood John M. , Lipson Evan J. , Ferris Robert L. , Bruno Tullia C. , Vignali Dario A.A.
Published: April 2023

Supplementary Data from Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells
Supplementary Data Legends from APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell–Mediated Antitumor Immune Responses
Authors: DiMarco Ashley V. , Qin Xiaodi , McKinney Brock J. , Garcia Nina Marie G. , Van Alsten Sarah C. , Mendes Elizabeth A. , Force Jeremy , Hanks Brent A. , Troester Melissa A. , Owzar Kouros , Xie Jichun , Alvarez James V.
Published: April 2023

Legends for Figures S1-S11 and Supplementary Tables S1-S3
Supplementary Data from Secreted Fas Decoys Enhance the Antitumor Activity of Engineered and Bystander T Cells in Fas Ligand–Expressing Solid Tumors
Authors: Bajgain Pradip , Torres Chavez Alejandro G. , Balasubramanian Kishore , Fleckenstein Lindsey , Lulla Premal , Heslop Helen E. , Vera Juan , Leen Ann M.
Published: April 2023

Supplementary Data from Secreted Fas Decoys Enhance the Antitumor Activity of Engineered and Bystander T Cells in Fas Ligand–Expressing Solid Tumors
Supplementary Tables from Hippo Signaling Pathway Regulates Cancer Cell–Intrinsic MHC-II Expression
Authors: Zeng Zexian , Gu Shengqing Stan , Ouardaoui Nofal , Tymm Carly , Yang Lin , Wong Cheryl J. , Li Dian , Zhang Wubing , Wang Xiaoqing , Weirather Jason L. , Rodig Scott J. , Hodi F. Stephen , Brown Myles , Liu X. Shirley
Published: April 2023

Supplementary Tables S1-S4
Supplementary Data from Hippo Signaling Pathway Regulates Cancer Cell–Intrinsic MHC-II Expression
Authors: Zeng Zexian , Gu Shengqing Stan , Ouardaoui Nofal , Tymm Carly , Yang Lin , Wong Cheryl J. , Li Dian , Zhang Wubing , Wang Xiaoqing , Weirather Jason L. , Rodig Scott J. , Hodi F. Stephen , Brown Myles , Liu X. Shirley
Published: April 2023

Supplementary Data from Hippo Signaling Pathway Regulates Cancer Cell–Intrinsic MHC-II Expression
Supplementary Figure from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy
Authors: Nielsen Morten , Presti Mario , Sztupinszki Zsofia , Jensen Agnete Witness Præst , Draghi Arianna , Chamberlain Christopher Aled , Schina Aimilia , Yde Christina Westmose , Wojcik John , Szallasi Zoltan , Crowther Michael Douglas , Svane Inge Marie , Donia Marco
Published: April 2023

Supplementary Figure from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy
Supplementary Table from Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells
Authors: Margolis Naama , Moalem Hanna , Meirson Tomer , Galore-Haskel Gilli , Markovits Ettai , Baruch Erez N. , Vizel Bella , Yeffet Avner , Kanterman-Rifman Julia , Debby Assaf , Besser Michal J. , Schachter Jacob , Markel Gal
Published: April 2023

Supplementary Table from Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells
Supplementary Data from In Vivo Syngeneic Tumor Models with Acquired Resistance to Anti–PD-1/PD-L1 Therapies
Authors: Denis Morgane , Grasselly Chloé , Choffour Pierre-Antoine , Wierinckx Anne , Mathé Doriane , Chettab Kamel , Tourette Anne , Talhi Nolan , Bourguignon Aurore , Birzele Fabian , Kress Elsa , Jordheim Lars Petter , Klein Christian , Matera Eva-Laure , Dumontet Charles
Published: April 2023

Supplementary Data from In Vivo Syngeneic Tumor Models with Acquired Resistance to Anti–PD-1/PD-L1 Therapies
Table S1-5 from Extracellular Vesicle–Packaged circATP2B4 Mediates M2 Macrophage Polarization via miR-532-3p/SREBF1 Axis to Promote Epithelial Ovarian Cancer Metastasis
Authors: Wang Fang , Niu Yuequn , Chen Kelie , Yuan Xiaoyu , Qin Yuheng , Zheng Fang , Cui Zhenyan , Lu Weiguo , Wu Yihua , Xia Dajing
Published: April 2023

Supplementary table S1-5
Figure S2 from Extracellular Vesicle–Packaged circATP2B4 Mediates M2 Macrophage Polarization via miR-532-3p/SREBF1 Axis to Promote Epithelial Ovarian Cancer Metastasis
Authors: Wang Fang , Niu Yuequn , Chen Kelie , Yuan Xiaoyu , Qin Yuheng , Zheng Fang , Cui Zhenyan , Lu Weiguo , Wu Yihua , Xia Dajing
Published: April 2023

Supplementary Figure S2
Supplementary Figure from Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis
Authors: Virgilio Tommaso , Bordini Joy , Cascione Luciano , Sartori Giulio , Latino Irene , Molina Romero Daniel , Leoni Cristina , Akhmedov Murodzhon , Rinaldi Andrea , Arribas Alberto J. , Morone Diego , Seyed Jafari S. Morteza , Bersudsky Marina , Ottolenghi Aner , Kwee Ivo , Chiaravalli Anna Maria , Sessa Fausto , Hunger Robert E. , Bruno Antonino , Mortara Lorenzo , Voronov Elena , Monticelli Silvia , Apte Ron N. , Bertoni Francesco , Gonzalez Santiago F.
Published: April 2023

Supplementary Figure from Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis
Supplementary Figures S1 to S7 from Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR
Authors: Chen Ximin , Chen Laurence C. , Khericha Mobina , Meng Xiangzhi , Salvestrini Emma , Shafer Amanda , Iyer Neha , Alag Anya S. , Ding Yunfeng , Nicolaou Demetri M. , Chen Yvonne Y.
Published: April 2023

Figures S1 to S7
Supplementary Data S4 from Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR
Authors: Chen Ximin , Chen Laurence C. , Khericha Mobina , Meng Xiangzhi , Salvestrini Emma , Shafer Amanda , Iyer Neha , Alag Anya S. , Ding Yunfeng , Nicolaou Demetri M. , Chen Yvonne Y.
Published: April 2023

List of gene names and FPKM values from bulk RNA-seq on unstimulated ex vivo-cultured T cells (Fig. 4F).
Supplementary Data S2 from Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR
Authors: Chen Ximin , Chen Laurence C. , Khericha Mobina , Meng Xiangzhi , Salvestrini Emma , Shafer Amanda , Iyer Neha , Alag Anya S. , Ding Yunfeng , Nicolaou Demetri M. , Chen Yvonne Y.
Published: April 2023

List of gene names and FPKM values from bulk RNA-seq on T cells harvested from tumor-bearing mice (Fig. 4A-D, F and Supplementary Fig. S7).
Data from NKG7 Is Required for Optimal Antitumor T-cell Immunity
Authors: Li Xian-Yang , Corvino Dillon , Nowlan Bianca , Aguilera Amelia Roman , Ng Susanna S. , Braun Matthias , Cillo Anthony R. , Bald Tobias , Smyth Mark J. , Engwerda Christian R.
Published: April 2023

Abstract
Tumor antigen-specific CD8+ T cells play a critical role in antitumor immunity. Clinical trials reinvigorating the immune system via immune checkpoint blockade (ICB) have shown remarkable clinical promise. Numerous studies have identified an association between NKG7 expression and patient outcome across different malignancies. However, aside from these correlative observations, very little is known about NKG7 and its role in antitumor immunity. Herein, we utilized single-cell RNA sequencing (scRNA-seq) datasets, NKG7-deficient mice, NKG7-reporter mice, and mouse tumor models to investigate the role of NKG7 in neoantigen-mediated tumor rejection and ICB immunotherapy. scRNA-seq of tumors from patients with metastatic melanoma or head and neck squamous cell carcinoma revealed that NKG7 expression is highly associated with cytotoxicity and specifically expressed by CD8+ T cells and natural killer (NK) cells. Furthermore, we identified a key role for NKG7 in controlling intratumor T-cell accumulation and activation. NKG7 was upregulated on intratumor antigen-specific CD8+ T cells and NK cells and required for the accumulation of T cells in the tumor microenvironment. Accordingly, neoantigen-expressing mouse tumors grew faster in Nkg7-deficient mice. Strikingly, efficacy of single or combination ICB was significantly reduced in Nkg7-deficient mice.

See related article by Wen et al., p. 162
Table S3 from An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities
Authors: Flümann Ruth , Rehkämper Tim , Nieper Pascal , Pfeiffer Pauline , Holzem Alessandra , Klein Sebastian , Bhatia Sanil , Kochanek Moritz , Kisis Ilmars , Pelzer Benedikt W. , Ahlert Heinz , Hauer Julia , da Palma Guerreiro Alexandra , Ryan Jeremy A. , Reimann Maurice , Riabinska Arina , Wiederstein Janica , Krüger Marcus , Deckert Martina , Altmüller Janine , Klatt Andreas R. , Frenzel Lukas P. , Pasqualucci Laura , Béguelin Wendy , Melnick Ari M. , Sander Sandrine , Montesinos-Rongen Manuel , Brunn Anna , Lohneis Philipp , Büttner Reinhard , Kashkar Hamid , Borkhardt Arndt , Letai Anthony , Persigehl Thorsten , Peifer Martin , Schmitt Clemens A. , Reinhardt Hans Christian , Knittel Gero
Published: April 2023

BCR sequencing
Supplementary Figure 6 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 6
Supplementary Figure 5 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 5
Supplementary Table S8 from Large-scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers
Authors: Feusier Julie E. , Arunachalam Sasi , Tashi Tsewang , Baker Monika J. , VanSant-Webb Chad , Ferdig Amber , Welm Bryan E. , Rodriguez-Flores Juan L. , Ours Christopher , Jorde Lynn B. , Prchal Josef T. , Mason Clinton C.
Published: April 2023

CHIP mutations not exclusive to hotspots
Supplementary Table S7 from Large-scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers
Authors: Feusier Julie E. , Arunachalam Sasi , Tashi Tsewang , Baker Monika J. , VanSant-Webb Chad , Ferdig Amber , Welm Bryan E. , Rodriguez-Flores Juan L. , Ours Christopher , Jorde Lynn B. , Prchal Josef T. , Mason Clinton C.
Published: April 2023

Additional mutations meeting the criteria for relaxed CHIP
Supplementary Table S3 from Large-scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers
Authors: Feusier Julie E. , Arunachalam Sasi , Tashi Tsewang , Baker Monika J. , VanSant-Webb Chad , Ferdig Amber , Welm Bryan E. , Rodriguez-Flores Juan L. , Ours Christopher , Jorde Lynn B. , Prchal Josef T. , Mason Clinton C.
Published: April 2023

Hotspots difficult to confidently assess for CHIP
Supplementary Table S1 from Large-scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers
Authors: Feusier Julie E. , Arunachalam Sasi , Tashi Tsewang , Baker Monika J. , VanSant-Webb Chad , Ferdig Amber , Welm Bryan E. , Rodriguez-Flores Juan L. , Ours Christopher , Jorde Lynn B. , Prchal Josef T. , Mason Clinton C.
Published: April 2023

Recurrently reported mutation hotspots
Supplementary Information from Large-scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers
Authors: Feusier Julie E. , Arunachalam Sasi , Tashi Tsewang , Baker Monika J. , VanSant-Webb Chad , Ferdig Amber , Welm Bryan E. , Rodriguez-Flores Juan L. , Ours Christopher , Jorde Lynn B. , Prchal Josef T. , Mason Clinton C.
Published: April 2023

Supplementary Methods and Supplementary Figures
Supplementary Data from Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis
Authors: Wang Victoria E. , Blaser Bradley W. , Patel Ravi K. , Behbehani Gregory K. , Rao Arjun A. , Durbin-Johnson Blythe , Jiang Tommy , Logan Aaron C. , Settles Matthew , Mannis Gabriel N. , Olin Rebecca , Damon Lloyd E. , Martin Thomas G. , Sayre Peter H. , Gaensler Karin M. , McMahon Emma , Flanders Michael , Weinberg Vivian , Ye Chun J. , Carbone David P. , Munster Pamela N. , Fragiadakis Gabriela K. , McCormick Frank , Andreadis Charalambos
Published: April 2023

Supplementary Data from Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis
Supplementary Table 6 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia
Authors: Yan Dongqing , Franzini Anca , Pomicter Anthony D. , Halverson Brayden J. , Antelope Orlando , Mason Clinton C. , Ahmann Jonathan M. , Senina Anna V. , Vellore Nadeem A. , Jones Courtney L. , Zabriskie Matthew S. , Than Hein , Xiao Michael J. , van Scoyk Alexandria , Patel Ami B. , Clair Phillip M. , Heaton William L. , Owen Shawn C. , Andersen Joshua L. , Egbert Christina M. , Reisz Julie A. , D'Alessandro Angelo , Cox James E. , Gantz Kevin C. , Redwine Hannah M. , Iyer Siddharth M. , Khorashad Jamshid S. , Rajabi Nima , Olsen Christian A. , O'Hare Thomas , Deininger Michael W.
Published: April 2023

Oligonucleotide sequences.
Supplementary Table 3 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia
Authors: Yan Dongqing , Franzini Anca , Pomicter Anthony D. , Halverson Brayden J. , Antelope Orlando , Mason Clinton C. , Ahmann Jonathan M. , Senina Anna V. , Vellore Nadeem A. , Jones Courtney L. , Zabriskie Matthew S. , Than Hein , Xiao Michael J. , van Scoyk Alexandria , Patel Ami B. , Clair Phillip M. , Heaton William L. , Owen Shawn C. , Andersen Joshua L. , Egbert Christina M. , Reisz Julie A. , D'Alessandro Angelo , Cox James E. , Gantz Kevin C. , Redwine Hannah M. , Iyer Siddharth M. , Khorashad Jamshid S. , Rajabi Nima , Olsen Christian A. , O'Hare Thomas , Deininger Michael W.
Published: April 2023

Standard hematologic parameters in SIRT5-/- mice and SIRT5+/+ littermates.
Supplemental Table 1 from Predictors of Humoral Response to SARS-CoV-2 Vaccination after Hematopoietic Cell Transplantation and CAR T-cell Therapy
Authors: Tamari Roni , Politikos Ioannis , Knorr David A. , Vardhana Santosha A. , Young Jennifer C. , Marcello LeeAnn T. , Doddi Sital , Devlin Sean M. , Ramanathan Lakshmi V. , Pessin Melissa S. , Dunn Erica , Palazzo Meighan , Bravo Christina D. , Papanicolaou Genovefa A. , Kamboj Mini , Perales Miguel Angel , Chung David J. , Shah Gunjan L.
Published: April 2023

<50>50 Anti-SARS-CoV-2 spike IgG, <30>30 Neutralizing antibodies
Supplementary Data from Blockade or Deletion of IFNγ Reduces Macrophage Activation without Compromising CAR T-cell Function in Hematologic Malignancies
Authors: Bailey Stefanie R. , Vatsa Sonika , Larson Rebecca C. , Bouffard Amanda A. , Scarfò Irene , Kann Michael C. , Berger Trisha R. , Leick Mark B. , Wehrli Marc , Schmidts Andrea , Silva Harrison , Lindell Kevin A. , Demato Ashley , Gallagher Kathleen M.E. , Frigault Matthew J. , Maus Marcela V.
Published: April 2023

Supplementary Data from Blockade or Deletion of IFNγ Reduces Macrophage Activation without Compromising CAR T-cell Function in Hematologic Malignancies
Supplementary File 1 from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
Authors: Marastoni Stefano , Madariaga Ainhoa , Pesic Aleksandra , Nair Sree Narayanan , Li Zhu Juan , Shalev Zvi , Ketela Troy , Colombo Ilaria , Mandilaras Victoria , Cabanero Michael , Bruce Jeff P. , Li Xuan , Garg Swati , Wang Lisa , Chen Eric X. , Gill Sarbjot , Dhani Neesha C. , Zhang Wenjiang , Pintilie Melania , Bowering Valerie , Koritzinsky Marianne , Rottapel Robert , Wouters Bradly G. , Oza Amit M. , Joshua Anthony M. , Lheureux Stephanie
Published: April 2023

CRISPR screen OVCAR5. Results of the Itra sensitizing CRISPR screen on the OVCAR5 cell line using drugZ algorithm.
Supplementary Table 6 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Authors: George Joshy , Chen Yaohui , Abdelfattah Nourhan , Yamamoto Keiko , Gallup Thomas D. , Adamson Scott I. , Rybinski Brad , Srivastava Anuj , Kumar Parveen , Lee Min Gyu , Baskin David S. , Jiang Wen , Choi Jong Min , Flavahan William , Chuang Jeffrey H. , Kim Betty Y.S. , Xu Jiaqiong , Jung Sung Yun , Yun Kyuson
Published: April 2023

Supplementary Table 6: DEG in LDE vs control treated fSMO;GFAP-cre tumors
Supplementary Table 5 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Authors: George Joshy , Chen Yaohui , Abdelfattah Nourhan , Yamamoto Keiko , Gallup Thomas D. , Adamson Scott I. , Rybinski Brad , Srivastava Anuj , Kumar Parveen , Lee Min Gyu , Baskin David S. , Jiang Wen , Choi Jong Min , Flavahan William , Chuang Jeffrey H. , Kim Betty Y.S. , Xu Jiaqiong , Jung Sung Yun , Yun Kyuson
Published: April 2023

Supplementary Table 5: mutational profiles for Fsmo;GFAP-cre SD-CSC tumors
Supplementary Table 4 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Authors: George Joshy , Chen Yaohui , Abdelfattah Nourhan , Yamamoto Keiko , Gallup Thomas D. , Adamson Scott I. , Rybinski Brad , Srivastava Anuj , Kumar Parveen , Lee Min Gyu , Baskin David S. , Jiang Wen , Choi Jong Min , Flavahan William , Chuang Jeffrey H. , Kim Betty Y.S. , Xu Jiaqiong , Jung Sung Yun , Yun Kyuson
Published: April 2023

Supplementary Table 4: mutational profiles for Ptch;p53 SI-CSC tumors
Figure S2 from Under-Representation of Racial Groups in Genomics Studies of Gastroenteropancreatic Neuroendocrine Neoplasms
Authors: Herring Brendon R. , Bonner Andrew , Guenter Rachael E. , Vickers Selwyn , Yates Clayton , Lee Goo , Dhall Deepti , Chen Herbert , Rose J. Bart
Published: April 2023

Comparison of racial group representation in GEP-NEN genomics, cancer genomics, and in the US population per 2020 census data.
Supplementary Figure S2 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

The gating ancestry for the populations in the study of D2.A1 model
Supplementary Table TS2 from Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
Authors: Frank Malene S. , Andersen Christina S.A. , Ahlborn Lise B. , Pallisgaard Niels , Bodtger Uffe , Gehl Julie
Published: April 2023

Primer sequences
Supplementary Figure FS6 from Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
Authors: Frank Malene S. , Andersen Christina S.A. , Ahlborn Lise B. , Pallisgaard Niels , Bodtger Uffe , Gehl Julie
Published: April 2023

Patients with non-conclusive scan evaluations
Figure S8 from Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
Authors: Kacher Jamila , Manches Olivier , Aspord Caroline , Sartelet Hervé , Chaperot Laurence
Published: April 2023

Supplementary figure 8 shows HLA class I level of expression in NB cell lines, and heat map illustrating relations between chemokines, immune cell subsets and HLA class I associated genes levels.
Figure S6 from Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
Authors: Kacher Jamila , Manches Olivier , Aspord Caroline , Sartelet Hervé , Chaperot Laurence
Published: April 2023

Supplementary figure 6 shows differential CCL2 level according to MYCN amplification status in GSE 3960, and correlations between CCL2 level and immune cell infiltrate
Supplementary Methods 1 from A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis
Authors: Bora-Singhal Namrata , Saha Biswarup , Mohankumar Durairaj , Padmanabhan Jaya , Coppola Domenico , Chellappan Srikumar
Published: April 2023

Details of experimental methods
Figure S5 from Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma
Authors: Christenson Eric S. , Lim Su Jin , Durham Jennifer , De Jesus-Acosta Ana , Bever Katherine , Laheru Daniel , Ryan Amy , Agarwal Parul , Scharpf Robert B. , Le Dung T. , Wang Hao
Published: April 2023

Supplemental Figure 5. Post-treatment Median VAF Predicts Progression-Free Survival. To assess whether Median mutation variant allele fraction (VAF) in cell-free DNA (cfDNA) predicted progression-free survival (PFS) and overall survival (OS), we sequenced cfDNA samples taken prior to treatment initiation and after 2 cycles of GAX-CI (on-treatment). The change in Median VAF was calculated was the percentage change from post- to pre-treatment. Patients were stratified by whether they had a higher (post-tx high) or lower (post-tx low) than the median post-treatment KRAS VAF, and a larger (change high) or smaller (change low) than the median of change in KRAS VAF with treatment. This demonstrated a statistically improved PFS with a lower post-treatment (after 2 cycles of treatment) Median mutation VAF (panel A). Post-treatment median mutation VAF did not predict OS (panel B). Change in Median mutation VAF with 2 cycles of treatment was not associated with a statistically improved PFS (panel C) or OS (panel D).
Figure S4 from Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma
Authors: Christenson Eric S. , Lim Su Jin , Durham Jennifer , De Jesus-Acosta Ana , Bever Katherine , Laheru Daniel , Ryan Amy , Agarwal Parul , Scharpf Robert B. , Le Dung T. , Wang Hao
Published: April 2023

Supplemental Figure 4. Spaghetti plot of tumor mutation VAF changes with 2 cycles of GAX-CI. To determine the impact of GAX-CI on the allelic frequency of mutations detected in ctDNA, we measured the VAF of these mutations pre-treatment and after 2 cycles of GAX-CI. The mutations detected for a given patient were plotted using a spaghetti plot to provide a visual representation of the change in VAF with treatment.
Figure S2 from Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma
Authors: Christenson Eric S. , Lim Su Jin , Durham Jennifer , De Jesus-Acosta Ana , Bever Katherine , Laheru Daniel , Ryan Amy , Agarwal Parul , Scharpf Robert B. , Le Dung T. , Wang Hao
Published: April 2023

Supplemental Figure 2. Scatterplots comparing baseline RECIST tumor measurements with baseline cell-free DNA (cfDNA) biomarkers. To determine the relationship between baseline tumor mutational variant allele frequency (VAFs) and total tumor burden we compared baseline tumor burden as measured by RECIST measurements of evaluable lesions (sum of diameters in mm) with KRAS (panel A) and TP53 (panel B) VAFs for these tumors at the same time point. These data demonstrated no statistically significant relationship between baseline cfDNA VAF levels and RECIST measurements on CT scan.
Supplementary Data from Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer
Authors: Sokač Mateo , Ahrenfeldt Johanne , Litchfield Kevin , Watkins Thomas B.K. , Knudsen Michael , Dyrskjøt Lars , Jakobsen Martin R. , Birkbak Nicolai J.
Published: April 2023

Supplementary data
Table TS1 from Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
Authors: Widmer Carmen A. , Klebic Ismar , Domanitskaya Natalya , Decollogny Morgane , Howald Denise , Siffert Myriam , Essers Paul , Nowicka Zuzanna , Stokar-Regenscheit Nadine , van de Ven Marieke , de Korte-Grimmerink Renske , Galván José A. , Pritchard Colin E.J. , Huijbers Ivo J. , Fendler Wojciech , Vens Conchita , Rottenberg Sven
Published: April 2023

gRNA oligos used for the generation of Lrrc8a or Lrrc8d-knockout cell lines, organoids and tumors
Figure FS2 from Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
Authors: Widmer Carmen A. , Klebic Ismar , Domanitskaya Natalya , Decollogny Morgane , Howald Denise , Siffert Myriam , Essers Paul , Nowicka Zuzanna , Stokar-Regenscheit Nadine , van de Ven Marieke , de Korte-Grimmerink Renske , Galván José A. , Pritchard Colin E.J. , Huijbers Ivo J. , Fendler Wojciech , Vens Conchita , Rottenberg Sven
Published: April 2023

Blasticidin and Pt treatment of Lrrc8a or Lrrc8d rescue cell lines data associated with main Figure 1
Supplementary Table S4 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Head and neck cancer patient characteristics.
Supplementary Table S3 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Gastric cancer patient characteristics.
Supplementary Table S1 from A Phase IB Trial of the PI3K Inhibitor Alpelisib and Weekly Cisplatin in Patients with Solid Tumor Malignancies
Authors: Tsang Erica S. , Aggarwal Rahul R. , Dhawan Mallika S. , Bergsland Emily K. , Alvarez Edwin A. , Calabrese Susan , Pacaud Romain , Garcia Jose , Fattah Delaire , Thomas Scott , Grabowsky Jennifer , Moasser Mark M. , Munster Pamela N.
Published: April 2023

A) Rationale for study drug dose interruption or reduction; B) Rationale for cisplatin dose interruption or reduction; C) Cisplatin dose intensity, stratified by dose level
Supplementary Table S1 from Assessment of Colorectal Cancer Screening Disparities in U.S. Men and Women Using a Demographically Representative Sample
Authors: Shah Sumit K. , Narcisse Marie-Rachelle , Hallgren Emily , Felix Holly C. , McElfish Pearl A.
Published: April 2023

Characteristics of Women and Men Who Were up-to-Date with the USPSTF CRC Screening Guidelines
Supplementary Figure S5 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Representative photos of mice injected at different sites.
Supplementary Table 6 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplemental Table 6: List of extracellular matrix genes enriched in PAK4 KO anti-PD-1 treated samples.
Supplementary Figure S3 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Peptide assay.
Supplementary Table 5 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplemental Table 5: Differential gene expression analysis between B16 PAK4 KO anti-PD-1 vs WT anti-PD-1 tumors in vivo at day 10. Showing genes with q < 0.05 and log2FC > 1 or < -1.
Supplementary Table 4 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplemental Table 4: Differential gene expression analysis between B16 PAK4 KO anti-PD-1 vs PAK4 KO isotype tumors in vivo at day 10. Showing genes with q < 0.05 and log2FC > 2 or < -2.
Supplementary Figure S2 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Additional analyses of scRNA-seq.
Supplementary Table 3 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplemental Table 3: Differential gene expression analysis between B16 KO and WT tumors in vivo at day 6. Showing genes with q < 0.05 and log2FC > 1 or < -1.
Supplementary Table 1 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplementary Table 1: Panel of immune markers for dendritic cell characterization.
Supplementary Figure 8 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplementary Figure 8: PAK4 KO in human melanoma cells impairs B-catenin/WNT signalling.
Table ST3 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Table S3 shows reasons for discontinuation with patient charateristics
Supplementary Materials and Methods SM1 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Supplementary Materials and Methods show the trial protocol
Figure S3 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S3 shows functional assessment of cancer therapy - general over time
Figure S10 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S10 shows emotional well-being over time by response
Supplementary Figure SF5 from Antibody Binding and Neutralization of Live SARS-CoV-2 Variants Including BA.4/5 Following Booster Vaccination of Patients with B-cell Malignancies
Authors: Chang Andres , Akhtar Akil , Lai Lilin , Orellana-Noia Victor M. , Linderman Susanne L. , McCook-Veal Ashley A. , Switchenko Jeffrey M. , Saini Manpreet , Valanparambil Rajesh M. , Blum Kristie A. , Allen Pamela B. , Lechowicz Mary Jo , Romancik Jason T. , Ayers Amy , Leal Alyssa , O'Leary Colin B. , Churnetski Michael C. , Baird Katelin , Kives Melissa , Wrammert Jens , Nooka Ajay K. , Koff Jean L. , Dhodapkar Madhav V. , Suthar Mehul S. , Cohen Jonathon B. , Ahmed Rafi
Published: April 2023

Supplemental Figure 5. Reduced IgG binding titers against the spike protein of SARS-CoV-2 variants in NHL/CLL patients.
Figure S3 from MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Authors: Fukasawa Kazuya , Lyu Jiajun , Kubo Takuya , Tanaka Yuki , Suzuki Akane , Horie Tetsuhiro , Tomizawa Akane , Osumi Ryoma , Iwahashi Sayuki , Tokumura Kazuya , Murata Misato , Kobayashi Masaki , Todo Tomoki , Hirao Atsushi , Hinoi Eiichi
Published: April 2023

Figure S3
Figure S2 from MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Authors: Fukasawa Kazuya , Lyu Jiajun , Kubo Takuya , Tanaka Yuki , Suzuki Akane , Horie Tetsuhiro , Tomizawa Akane , Osumi Ryoma , Iwahashi Sayuki , Tokumura Kazuya , Murata Misato , Kobayashi Masaki , Todo Tomoki , Hirao Atsushi , Hinoi Eiichi
Published: April 2023

Figure S2