bluuebunny/crossref_metadata_2025 huggingface dataset:
Penyebab Perubahan Ketebalan Carotid Intima-Media
Authors: Waskito Budi Arief
Published: August 2019

Atherosclerosis causes significant morbidity and mortality. Carotid intima-media thickness (CIMT) can predict the onset of cardiovascular and ischemic stroke in the future. CIMT, the measurement of atherosclerosis, is determined in vivo using carotid ultrasound. CIMT is associated with traditional cardiovascular risk factors such as age, sex, race, smoking habits, alcohol consumption, exercise habits, blood pressure, dyslipidemia, dietary patterns, medications used, glycemia, hyperuricemia, anthropometric parameters associated with obesity. In addition, CIMT is also associated with novel risk factors, ie genotypes, cardiovascular anthropometry parameters, rheumatoid arthritis, immunologic diseases, inflammatory cytokines, lipid peroxidation, chemocyte anthropometric parameters, infectious diseases, vitamin D, matrix metalloproteinases, and other diseases
Pengaruh C-Phycocyanin Terhadap Kadar Soluble Glikoprotein (Sgp130) Pada Trofoblas Tikus Wistar Yang Dipapar Interleukin-6 (IL-6)
Authors: Haryanti Elizabeth , Gondo Harry K
Published: August 2019

The placenta is a joint organ of the uterus surface mother and fetus. One of cytokines of the placenta is IL-6 which is essential for normal placental development and successful pregnancy. Sgp130 binds Interleukin-6-sIL-6R complex, so Interleukin-6 signal cannot be passed on. Both factors play an important role in pre-eclampsia which has high levels of IL-6 and sgp130. They are expected to be suppressed by administration of C-phycocyanin. The aim of this study to prove effect of C-phycocyanin on sgp130 levels among wistar rats’ trophoblasts exposed to IL-6. The design of the study was Experiment, Post Test Only Control, analyse with One way Anova. The samples were 25 rats divided four treatment groups. Dose of C-Phycocyanin (10mg, 20mg, 40mg). The results significant difference between control and treatment group IL-6, IL-6 + CPC10, IL-6 + CPC20. But there was no significant difference between control group and IL-6 + CPC40, sig value. 0.214 (sig. <0.05). Conclusion. There is an effect of C-Phycocyanin on Sgp130 levels in wistar rats’ trophoblasts exposed to IL-6 at a dose of C-Phycocyanin 40mg.
The Effect of Anti Masquito Electric Gas that Consist Allethrin That Influence The Weight and Colour of Rats Liver
Authors: Nurmawanti Nurmawanti , Soekanto Ayly
Published: August 2019

The aim of this research is to know the influence of anti mosquito electric gas that consisted Allethrin to the weight and colour of the rats liver. This research used an experimental method with the post test only  control group design.  The subject of this research is male rats weight of 150 grams each and total there was 24 rats that were divided to 4 groups. The first one, the  control groups (PO) was not given any of the gas, the second one, group 1 (P1) was given the gas for 4 hours everday, the third one, group  2 (P2), was given for 6 hours and last, group 3  (P3) was given 8 hours everyday. After later, on  30 Th day, the rats were terminated and being put in a surgery to remove their liver. This data was analyzed using SPPS for windows version 16. To see the differences in weight between the groups, it was analyzed using anova, and  to obtain the discoloration of the rats liver was analyzed using Kruskal Wallis Test. From the statistic tests, it show that there is significant difference in weight and color of liver in the group that α ≤ 0,05. According Anova Test, it shows that there is a significant difference α = 0,034 and from Kruskal Wallis test α = 0,013. In the conclusion anti mosquito electric gas that consist Allethrin affects the weight and the color of rats liver.
Difference of Effectiveness Acarbose with Ethanol Extract Purple Eggplant’s Peel (Solanum melongena L) to Reduce Blood Sugar Levels in White Rat (Rattus norvegicus) Induced by Sucrose
Authors: Budianto Nugroho Eko Wirawan , Hairullah Hairullah
Published: August 2019

Acarbose is an oligosaccharide human made who is a competitive inhibitor acarbose and can inhibit the action of the enzyme α-glucosidase, causing a slowdown in the digestion of carbohydrate compounds. Purple eggplant skin is included in the flavonoid compound. Purple eggplant  skin as well as an antioxidant that can control blood glucose levels and prevent complications of diabetes. Purple eggplant skin contains flavonoid kaempferol and has the effect of inhibiting the enzyme alpha-glucosidase. Based on these researchers want to know the difference in effectiveness between the ethanol extract of purple eggplant skin  and acarbose to decrease blood sugar levels of mice. The study population using white rats with a total sample size of 30 rats. Research data analysis using One Way Anova Test. Methods: Male rats strain Wistar were divided into 5 groups. 1) Control (CMC Na 1 ml io), 2) Group 1  (The ethanol extract of 50 mg / kg in the CMC Na io),  3) Group 2  (The ethanol extract 100 mg / kg in CMC Na io), 4) Group 3  (the ethanol extract 200 mg / kg in the CMC Na io), 5) Group 4 (Acarbose 4.5 mg / kg in distillated water io). The result showed ethanol extract of purple eggplant skin in group 2 showed the best effectiveness in lowering blood sugar levels of white rats by oral sucrose injection. And there is no significant difference between the effectiveness of the ethanol extract of purple eggplant skin and acarbose in lowering blood sugar levels of white rats by oral sucrose injection.
Junk Food Consumption as Risk Factor of Poly Cystic Ovarian Syndrome
Authors: Sompotan Leroy Lucano
Published: August 2019

Nowadays, infertile incidences in young married couple are increasing and the women got unreguler menstruation cycles that pretend a Poly Cystic Ovarian Syndrome (PCOS) predisposition. Accretion of PCOS incidences coincide with accretion of junk food (JF) consumption life style in women. This study is description from some literatures of predisposition of JF consumption life style towards PCOS incidence accretion. JF is being PCOS predisposition because its refined carbohydrate increasing insulin resistance risk; high glucose-salts-fats ingredients disturbing hormones balance; JF is processed using partial hydrogenated oil; frying of JF using oxidized oil that producing radical damage of the cell; JF is fried using high temperature over 100° celcius that inducing aldehid and keton formation; JF is fried using over 4 times heating. Thus, importance of education about JF consumption and healthy foods in family must be done since the child has born; socialization of JF hazard in the household scale; education of JF consumption and healthy foods in the school; restriction of business permit in JF; restriction and regulation of business advertisement in JF; accretion of business tax in JF; tightening of public regulation about healthy life style.Nowadays, infertile incidences in young married couple are increasing and the women got unreguler menstruation cycles that pretend a Poly Cystic Ovarian Syndrome (PCOS) predisposition. Accretion of PCOS incidences coincide with accretion of junk food (JF) consumption life style in women. This study is description from some literatures of predisposition of JF consumption life style towards PCOS incidence accretion. JF is being PCOS predisposition because its refined carbohydrate increasing insulin resistance risk; high glucose-salts-fats ingredients disturbing hormones balance; JF is processed using partial hydrogenated oil; frying of JF using oxidized oil that producing radical damage of the cell; JF is fried using high temperature over 100° celcius that inducing aldehid and keton formation; JF is fried using over 4 times heating. Thus, importance of education about JF consumption and healthy foods in family must be done since the child has born; socialization of JF hazard in the household scale; education of JF consumption and healthy foods in the school; restriction of business permit in JF; restriction and regulation of business advertisement in JF; accretion of business tax in JF; tightening of public regulation about healthy life style.
IgG and IgM titres Problems in Determining Diagnosis of Toxoplasmosis
Authors: Soedarto Soedarto
Published: August 2019

To determine acute Toxoplasma gondii infection in pregnant women, is of interest worldwide due to the risk of congenital toxoplasmosis. Ability to diagnose recently acquired infection in the pregnant woman and congenital infection in the fetus and newborn was improved. Interpreting on maternal serological screening tests by new methods  should not rely on a single sample test but need confirmatory testing through a nationally recognized reference laboratory if results of serological tests are positive.
The Effect of Black Cumin Seed (Nigella sativa l.) Extract to Alloxan Induces Pancreatic Tissue Catalase Enzyme Activity of Male Wistar Rats (Rattus norvegicus)
Authors: Achmad Qonita , Dikman Irmawati , Prabowo Sulistiana
Published: August 2019

Alloxan causes the formation of reactive oxygen through the reduction process of alloxan (dialuric acid) in the β cells of pancreas. Free radicals cause damage  and decrease catalase enzyme activity. Black cumin seeds extract which contain carotenoids, thymoquinone, carvacrol, 4-terpineol, t-anethole, and tert-butylhydroquinone (TBHQ) has antioxidant activity that is expected to inhibit reactive oxygen species (ROS) that is expected to increase pancreatic catalase activity. This study used 24 male Wistar rats, divided into 3 groups:1)group of rats fed with standard food, 2)group of rats induced by alloxan 125mg/kg /BB intraperitoneally on day 1, 3)groups of rats induced by alloxan 125mg/kg/BB intraperitoneally on day 1 and were given by black cumin seed extract 2500mg/kg/BB orally on day 4 until 17. On the 18th day of all rats were sacrificed and pancreatic tissue catalase activity were measured by the spectrophotometric method. The results of One-Way ANOVA showed significant difference (p=0.003) pancreatic tissue catalase activity of groups of rats fed with standard food (1696,96U/g±414,10U/g) compared with group of rats induced by alloxan (1287,58U/g±88,45U/g). There was significant difference (p=0.001) of pancreatic tissue catalase activity of groups of rats induced by alloxan (1287,58U/g±88,45U/g) with a group of rats induced by alloxan and given with black cumin seed extract (1764,83U/g±199,69U/g). The conclusion of this study showed that the administration of alloxan significantly decreased pancreatic tissue catalase activity of rat and black cumin seed extract significantly increased catalase activity because cumin extract has antioxidant effects.
Pengaruh Pemberian Ekstrak Alga Merah (gracilaria verrucosa) terhadap Aktivitas SGPT pada Tikus Putih (rattus norvegicus) Jantan Galur Wistar yang Diinduksi Parasetamol Dosis Tinggi
Authors: Fikri Akbar Maharudin , Tehupuring Sihning EJ
Published: August 2019

Background: Administration of high dose paracetamol may increase the metabolic pathways that produce N-acetyl-p-benzoquinonimin (NAPQI). NAPQI is a reactive substance, resulting liver tissue damage and increase SGPT activity. Red algae extract contains flavonoids that act as antioxidants.Objectives: This research aimed to determine the effect of red algae (Gracilaria verrucosa) extract to the activity of serum glutamic pyruvic transaminase (SGPT) in male Wistar rats (Rattus norvegicus) induced by high dose paracetamol.Methodology: This research used 24 animal of Male Wistar rats. These rats were divided into 3 groups: 1) group of rats fed with standard food; 2) group of rats given paracetamol 1750 mg/kg on day 10; and 3) group of rats given red algae extract 200 mg/kg/day on day 1-11 and paracetamol 1750mg/kg on day 10. On day 11, all rats were sacrificed and SGPT activities were measured by spectrophotometry method.Result: Mann-Whitney test results showed significant difference (p = 0.021) between SGPT activity of group of rats fed with standard food (=81.95±10.103 U/L) and group of rats induced by high dose paracetamol (=97.06±11.19 U/L). Furthermore, there was significant difference (p = 0.016) between SGPT activity of group of rats induced by high dose paracetamol (=97.06±11.19 U/L) and group of rats induced by high doses of paracetamol and fed with red algae extract (=82.73±11.233 U/L).Conclusion: The conclusion of this research showed that high dose paracetamol significantly increased SGPT activity and red algae extract significantly decreased SGPT activity because it contains flavonoids that act as antioxidants.
The Relationship Anxiety With Degree of Insomnia In The Elderly
Authors: Sincihu Yudhiakuari , Daeng B. Handoko , Yola Priska
Published: August 2019

Anxiety is a mental disorder common in elderly people. In the process of becoming elderly, feelings of anxiety arise as a normal response to situations that accompany development, change, new experiences and find meaning in life. Anxious looks from physiological symptoms such as shaking, sweating, heart work increases and psychological symptoms such as panic, tension, confusion, unable to concentrate. This condition will inhibit the elderly's bio-psycho-social condition in living the rest of his life. One effect is seen from their sleep problems. This is observational research with cross-sectional approach. Samples were taken by consecutive sampling technique. 43 elderly who met the exclusion criteria. Research location at Posyandu Lansia Mojo, Surabaya. Data collection using Hamilton Rating Scale for Anxiety and Insomnia Severity Index questionnaires. the results of the study described 41.9% of subjects with anxiety disorders and 67.4% of subjects had insomnia disorders. The cross-tabulation results showed 48% of subjects without anxiety can occur insomnia disorders and only mild anxiety alone can cause insomnia in 100% of subjects. Rank Spearman Test shows a very strong relationship between anxiety with the incidence of insomnia in the elderly (Sig .000; coefficient correlation .535).
Water Clover Extract in Liprotein Lipase enzyme Activity of The Rats with High Cholesterol Diet
Authors: Hayudanti Dewinta
Published: August 2019

Hypertriglyceridemia or high blood triglyceride levels is one of the lipid fraction disorders associated with an increased risk of cardiovascular disease. Flavonoids has an important role as cardioprotection by lowering triglyceride levels. The flavonoids in water clover contain 10,71 mg of extract. This research aims to prove that flavonoids can increase Lipoprotein Lipase enzymes activity. True experimental study used design pre-post test control group design in rats. The sample was selected based on by completed randomized design sampling to be devided into five groups, the control positive (n=5) were only given normal diet, control negative (n=5) were only given high cholesterol diet and treatment groups with three doses (n=15) were given cholesterol diet during the 7 days and water clover extract that intervention during the 14 days. The results of this research can increase activity of Lipoprotein Lipase enzymes as an influence of water clover extract based on Paired T-Test, before and after treatment there was a significant different (p<0.05). Activity of Lipoprotein Lipase enzymes in the negative control group and third treatment showed a significant difference (p.< 0.05) based on MANOVA (Multivariate Analyses of Variance). Conclusions of this research is water clover extract affecting increase Lipoprotein Lipase enzymes activity significantly.
Ekstrak Bawang Putih Siung Tunggal terhadap Aktivitas Enzim Lipoprotein Lipase pada Tikus Hiperkolesterol
Authors: Brouwer Juliana Veronica
Published: August 2019

Hiperkolesterolemia merupakan suatu keadaan dimana kadar kolesterol didalam darah mengalami peningkatan diatas angka rata-rata nilai normal yang telah di tetapkan secara standar. Terapi herbal tradisional merupakan terapi alternatif yang dapat digunakan untuk mencegah dan menurunkan kadar trigliserida di dalam darah. Salah satu pilihan terapi yang digunakan adalah bawang putih siung tunggal (Allium Sativum Linn.). Bawang putih siung tunggal memiliki kandungan antioksidan yang kuat yaitu flavonoid, apabila dengan rutin mengkonsumsinya dapat menurunkan kadar trigliserida didalam darah sehingga resiko penyakit degeneratif dapat dikurangi. Flavonoid adalah senyawa golongan polifenol. flavonoid memiliki kemampuan sebagai antikolesterol. Flavonoid bekerja pada banyak enzim dalam pembentukan kolesterol atau trigliserida, salah satunya adalah enzim lipoprotein lipase. Sehingga, apabila aktivitas enzim lipoprotein lipase meningkat, maka proses pembentukan trigliserida melalui mekanisme jalur eksogen di pembuluh darah terhambat sehingga kadar trigliserida dapat menurun. Penelitian ini menggunakan jenis penelitian eksperimental laboratorium dengan design Pre test- Post test Controlled. Menggunakan 5 kelompok dengan masing-masing kelompok menggunakan 5 ekor tikus. uji Paired T-Test  menunjukkan bahwa terdapat perbedaan aktivitas enzim lipoprotein lipase dengan nilai signifikansi (p < 0.05) sedangkan pada uji Manova, nilai signifikansi yang didapatkan adalah (p. < 0.05). Berdasarkan hasil penelitian, dapat disimpulkan bahwa pemberian ekstrak bawang putih siung tunggal dapat meningkatkan aktivitas dari enzim lipoprotein lipase.
Pengaruh Pemberian Teh Hijau (Camellia Sinensis) terhadap Aktivitas Superoksida Dismutase (SOD)
Authors: Mukty Ma'rifat Istiqa
Published: August 2019

Stres oksidatif dapat dipicu oleh paparan stres psikologis. Stres oksidatif dapat dikurangi dengan konsumsi zat antioksidan eksogen, teh hijau dianggap mampu menurunkan stres oksidatif. Tujuan penelitian ini untuk menguji pengaruh pemberian seduhan teh hijau terhadap glukosa darah, MDA dan aktivitas SOD pada tikus putih jantan Strain Wistar yang dipapar stres psikologis. Rancang bangun yang digunakan pada penelitian ini adalah Randomized Post Test Only Group Design. Terdapat 5 kelompok tikus, 2 adalah kelompok kontrol normal dan kelompok kontrol stres, serta 3 kelompok perlakuan. Sebelumnya tikus diberikan stres psikologis 1 x 24 jam berupa gangguan pola tidur jaga, sehingga didapatkan kondisi hewan coba yang mengalami stres oksidatif, kemudian dilakukan pemberian seduhan teh hijau pada kelompok perlakuan dengan dosis tunggal 3,6 ml/ekor pada jam ke-1 pada kelompok perlakuan 1, jam ke-6 pada kelompok perlakuan 2 dan jam ke-24 pada kelompok perlakuan 3. Analisis statistik menggunakan uji Manova. Hasil Berdasarkan analisis statistik menunjukkan bahwa terdapat perbedaan glukosa darah, dimana kelompok perlakuan menurun setelah jam ke-1 pemberian seduhan teh hijau, dan tetap bertahan di jam ke-6 dan ke-24, begitu pula dengan MDA, kelompok perlakuan menurun setelah jam ke-1 pemberian seduhan teh hijau, dan tetap bertahan di jam ke-6 dan ke-24. Sedangkan aktivitas SOD meningkat pada jam ke-1, kembali meningkat pada jam ke-6 dan meningkat maksimal pada jam ke-24 setelah pemberian teh hijau. Dosis tunggal seduhan teh hijau pada hewan coba yang mengalami stres oksidatif terbukti dapat menetralisir stres oksidatif pada jam ke-1 setelah pemberian teh hijau dan aktivitas antioksidannya masih bertahan sampai 24 jam.
Effect Administration of Ethanol Extract of Bitter Melon (Momordica Charantia L.) On The Reduction of MDA (Malondialdehyde) Levels Serum in Rats Given a High-Fat Diet
Authors: Andiani Andiani , Harsa Made Subhawa
Published: August 2019

Hyperlipidemia is a disease whichthe effect in increased fat levels in the blood. In hyperlipidemia, the condition of high oxidative stress is obtained due to the oxidation process of LDL (Low Density Lipoprotein) in the body, this condition showed by increased of MDA (Malondialdehyde) levels in serum. Bitter melon (Momordica Charantia L.) contains a lot of active ingredients, one of the ingredients of bitter melon that is thought to have antilipidemic effects is flavonoid compounds. This study was experimental study using a randomized posttest only control group design study with a sample size of 30 male white rats (Rattus norvegicus) wistar strain which was divided into 3 groups, namely K1, K2, and K3. In each group, different treatments are given. Negative control group (K1), given standard feed, water ad libitum; Positive control group (K2), given standard feed, high fat feed with a dose of 2.5 ml water ad libitum; The treatment group (K3) was given a standard diet, high-fat feed with a dose of 2.5 ml water ad libitum and extract of bitter melonat a dose of 250 mg / kg BB by orally every morning for 3 weeks. Data analysis using One Way Anova Test. From the results of the test shows the significance of p-value = 0.000 which is <α (0.05). The results showed that there was an effect of  administration ethanol extract of bitter melon (Momordica charantia L.) to decrease in serum MDA (malondialdehyde) levels in male white wistar rats (Rattus norvegicus) given a high-fat diet.
ІННОВАЦІЙНІ ТЕНДЕНЦІЇ СУЧАСНОЇ ЗАРУБІЖНОЇ ВИЩОЇ ОСВІТИ
Authors: Плисенко Галина Павлівна , Назаркевич Віктор Орестович
Published: August 2019

The article offers a review of innovative concepts in modern higher education along with providing the in-depth analysis and evidence summary of its key trends that are currently relevant and are gaining popularity in most world countries. Thus, the authors attempt to attain the research objective which is to explore the major global trends and innovations in the area of higher education as well as the opportunities for their application in domestic institutions of higher education. The study used general scientific and special research methods: scientific generalization and systematization – to reveal the characteristics of innovative international trends in higher education; comparative analysis – for mapping certain aspects of the national and world-class higher education; system analysis – to identify the factors driving innovation development in higher education; the logical synthesis – to explain the results of the study. The survey of modern global education trends has enabled to shape the following major innovation tendencies, such as: integration of systems thinking entailing the harmonization of assessment and grading systems and diplomas at different education levels to prevent duplication and improve timely accomplishment of training programs; creating the new and enhancing the current financial aid schemes and funding models that promote actual effective performance, etc.; human vs. artificial intelligence competition; building sustainable communities (from both, socio-cultural and economic perspectives); maintaining a combination of traditional and non-traditional learning which is primarily manifested through offering wider flexible opportunities for adults wishing to get tertiary education or undergo further retraining; identification and assessment of competences as well as ensuring training programs compliance with the needs of the contemporary labour market. It is argued that a failure to respond to the above challenges, the outdated higher education standards that are not keeping pace with technological progress, innovations and growing demand for relevant specialists in the labour market make many of the domestic education institutions lag behind. The education system also fails to pay due attention to modern realia of professional domain and applied issues of professional training which triggers devaluation of University degrees and hence leads to the imbalance in the labour market, characterized at present by a significant unemployment rate among persons with higher education.
СТРАТЕГІЧНІ ОРІЄНТИРИ ЗАБЕЗПЕЧЕННЯ ЕКОНОМІЧНОЇ БЕЗПЕКИ ІНВЕСТИЦІЙНОЇ ДІЯЛЬНОСТІ ПРОМИСЛОВИХ ПІДПРИЄМСТВ
Authors: Злотенко Олександр Борисович
Published: August 2019

The article seeks to explore the concepts of building strategy and strategic guidelines for industrial enterprises to ensure their economic security. It should be noted that in modern business settings, company strategy is of long-term character and is affected by a wide range of economic activity factors. Operating in industrial sector of the economy is associated with multicomponent production arrangements that challenge the need for high-quality technical support. In this regard, investment activity is of critical importance to industrial enterprises. Its key strategic priority is to promote research and development, technological and technical modernization of production. Within the scope of this study, the two issues of the industrial enterprise investment plan have been addressed, i.e. investment funds attracting and their placement. Investment generation to upgrade the production process, along with gaining additional benefits triggers certain risks inherent to such type of financial instruments. In the context of setting strategic guidelines for industrial enterprises, it is suggested to consider investment security as a subsystem and critical element in the economic security system. It is argued that investment security policy should be developed within the framework of tactical planning, since investment security is only part of the overall economic security paradigm. However, the outcomes of such activities should be anticipated at the stage of designing strategic guidelines for efficient enterprise functioning. While implementing the company strategy, it is proposed to divide the total range of tactical actions into two contingent groups: horizontal and vertical. Horizontal activities are targeted on enhancing the enterprise capacity building which in turn will make a resource base for facilitating the transition to the next stage of approaching the desired effect or a final goal. It is also argued that selecting strategic priorities and developing pathways to implement them is a complex and multifaceted process that requires a thorough approach for setting strategic objectives as well as elaborating interim stages in total enterprise development plan.
DIAGNOSTICS OF EXTERNAL ENVIRONMENT EFFECTS UPON ENTERPRISE COMPETITIVE POSITIONS IN THE CONTEXT OF ITS ECONOMIC SECURITY
Authors: Arefieva Olena V. , Miahkykh Iryna M. , Shkoda Mariana S.
Published: August 2019

The article reveals the nature of a competitive enterprise, identifies the external environment factors affect the enterprise competitive position and provides insights on the enterprise economic security concept. In thus study, the essence of the enterprise economic security category is viewed as a specifically built system of preventive measures aimed at conducting targeted permanent activities to ensure sustainable efficient enterprise performance through effective management of negative impact factors that affect hider its successful operation. The paper provides the analysis of a range of external factors that can damage the enterprise economy along with suggesting the structuring of external factors of competitiveness with regard to each stage of the enterprise business plan implementation. The functional objectives of the enterprise economic security and specifics of shaping the economic security diagnostics system are discussed. The study also offers the review on the methods used to diagnose the environment effects on the enterprise competitive position in the context of its economic security. It is argued that the most significant indicators estimated by a number of selected criteria (structural elements) of a business competitive position within the system for enterprise economic security diagnostics are the following: the level of security by the financial component, the level of security by personnel component, the level of security by innovation and technology component, the level of security by political and legal component, the level of security by analytical information component and the level of security by economic component. The paper also suggests the methods and tools for business economic security diagnostics and explores the key objectives of the enterprise economic security management system.
AKULTURASI BUDAYA SUNDA DAN JEPANG MELALUI PENGGUNAAN IGARI LOOK DALAM TATA RIAS SUNDA SIGER
Authors: Desiana Fauziah Ismi , Dienaputra Reiza D.
Published: August 2019

Akulturasi budaya Jepang dan Sunda dalam bingkai tata rias Sunda Siger membuktikan bahwa tata rias tradisional dapat dikemas modern dalam balutan teknik Igari Look. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif. Pengumpulan data didapatkan dari wawancara dengan make-up artist yang menggunakan teknik make-up Igari Look dalam tata rias Sunda Siger dan aktif mengunggah hasil tata riasnya dalam sebuah portofolio di Instagram. Akulturasi kebudayaan Sunda dan Jepang dalam tata rias Sunda Siger merupakan bukti bahwa masyarakat Sunda terbuka dengan situasi multikultural. Keberadaan Igari Look dalam bingkai tata rias Sunda Siger pada hakikatnya bukan bertujuan untuk memarjinalkan makna filosofis dan historis dalam setiap unsur tata rias Sunda Siger, namun proses inovasi dari make-up artist ini perlu dimaknai sebagai sumbangsih untuk menghidupkan kembali tata rias tradisional agar lebih diminati oleh kaum muda. Acculturation of Japanese and Sundanese culture in frame Sunda Siger cosmetology proves that traditional cosmetology can be filled with modern dressing in the Igari Look technique. This study uses qualitative methods using descriptive. Data collection was obtained from interviews with make-up artists who used the Igari Look make-up technique in the Sunda Siger makeup and actively uploaded the makeup results in a portfolio on Instagram. Acculturation of Sundanese and Japanese culture in Sundanese Siger makeup is proof that Sundanese society is open with multiculturalism. The existence of Igari Look in the Sunda Siger makeup frame in essence is not an agreement to marginalize philosophical and historical meanings in any Sundanese Siger makeup, the innovation process of this make-up artist needs to be interpreted as cleft of young people.
SENI BORDIR TASIKMALAYA DALAM KONSTELASI ESTETIK DAN IDENTITAS
Authors: Nero Agus , Sofianto Kunto , Sutirman Maman , Suganda Dadang
Published: August 2019

Penelitian ini berjudul “Seni Bordir Tasikmalaya dalam Konstelasi Estetik dan Identitas”. Penelitian ini mengkaji seni bordir Tasikmalaya dilihat dari aspek estetik dan identitas. Metode yang digunakan adalah metode deskriptif-analitik. Teknik pengumpulan data dalam penelitian ini adalah survei ke lapangan melalui wawancara, pengamatan secara langsung, dan pengambilan sumber-sumber tertulis dari masyarakat dan pemerintah setempat. Sumber data yang digunakan dalam penelitian ini adalah data lapangan melalui participant observation sebagai data primer dan sumber kepustakan sebagai data sekunder. Objek penelitian ini adalah kerajinan bordir di Tasikmalaya. Hasil dari penelitian ini adalah bahwa latar kultural yang mengawali lahir dan berkembangnya kerajinan bordir Tasikmalaya adalah kondisi kultural Tasikmalaya yang identik dengan aspek religi. Perkembangan kerajinan bordir Tasikmalaya telah mengalami perluasan ke arah dimensi pemaknaan, tujuan, hingga pengaruh estetika modern, pada masanya nanti telah berpengaruh pada adanya bauran estetik antara estetika tradisional dan estetika modern.This study entitled "Tasikmalaya Embroidery Art in Estetic Constelation and Identity". This study reviewed Tasikmalaya embroidery art from the aspects of aesthetic and identity. The method used in this research is descriptive-analytic method. Data collection techniques in this study is a survey of the field through interviews, direct observations, and taking written sources from the community and local government.The object of this study is embroidery in Tasikmalaya.The results obtained from this study is that the cultural background that started the birth embroidery cultural conditions of Tasikmalaya is identical with the religious aspect. Tasikmalaya embroidery developments have expanded toward the dimension of meaning, purpose, to the influence of modern aesthetics, in his time later have an effect on their aesthetic mix between traditional aesthetics and modern aesthetics.
PERANAN WANITA DALAM TRADISI LISAN CARITA PANTUN NYAI SUMUR BANDUNG
Authors: Purnama Yuzar
Published: August 2019

Isu gender memang tidak pernah putus dari perbincangan. Ketika seorang wanita berjuang untuk menuntut persamaan hak, dibalik itu ada pula wanita yang justru merendahkan martabatnya sebagai makhluk yang memiliki derajat yang sama dengan lain jenis. Pada kesempatan ini penulis ingin melihat lebih jauh tentang peran wanita dalam tradisi lisan Carita Pantun Nyai Sumur Bandung. Penelitian ini menggunakan metode deskripsi dengan pendekatan kualitatif. Batasan materi meliputi tradisi lisan, Carita Pantun, dan peranan tokoh wanita Nyai Sumur Bandung dalam tradisi lisan Carita Pantun. Kesimpulan, peranan seorang wanita yang bernama Nyai Sumur Bandung dari Kerajaan (Negara) Bitung Wulung yang berkiprah di Kerajaan Kuta Waringin dengan memiliki karakter yang kokoh dalam pendirian, tangguh, hati-hati, dan arif bijaksana.    Gender issues have never stopped being discussed. When a woman struggles to demand equality, behind that there are also women who actually lower their dignity as beings who have the same degree with other types. On this occasion the author would like to see more about the role of women in the oral tradition of Carita Pantun Nyai Sumur Bandung. This study uses a description method with a qualitative approach. The material boundaries included oral traditions, traditional poetry (Carita Pantun), and the role of female characters Nyai Sumur Bandung in the oral tradition of traditional poetry (Carita Pantun). Conclusion, the role of a woman named Nyai Sumur Bandung from the Kingdom Bitung Wulung who is active in the Kingdom of Kuta Waringin by having a strong character in stance, toughness, caution, and wisdom.
TARI GENDING SRIWIJAYA: MORALITAS DALAM REFLEKSI HISTORIS CIVIL SOCIETY
Authors: Mareta Yoan , Sariyatun Sariyatun , Sutimin Leo Agung
Published: August 2019

Tari Gending Sriwijaya adalah tari tradisional yang mengandung unsur budaya Palembang di setiap bagiannya. Setelah memicu kontroversi kontemporer yang menganjurkan penghapusan tari Gending Sriwijaya, tulisan ini hadir sebagai ungkapan kritis menolak konsepsi tersebut. Pentingnya warisan budaya dalam konteks kebudayaan haruslah disajikan sebagai acuan edukasi sebab kehadirannya merupakan bentuk historical value. Tujuan penulisan ini adalah kajian tari Gending Sriwijaya berfokus pada tafsir gerak yang diperagakan oleh penari melalui metode penelitian fenomenologi, guna mencari nilai moralitas yang terkandung dalam gerak tari dan mencari refleksi historis civil society dalam orientasi nilai. Hasil pembahasan: 1) Historisitas tari Gending Sriwijaya; 2) Tafsir gerak tari Gending Sriwijaya dalam kajian nilai moralitas; 3) Nilai refleksi historis civil society. Tari Gending Sriwijaya sebaiknya menjadi orientasi logis dalam pengejawantahan tari sebagai refleksi nilai historis, sebab kebutuhannya menyokong adab generasi mendatang yang berkontribusi terhadap kesuksesan visi civil society.Gending Sriwijaya dance is a traditional dance that contains elements of Palembang culture in every part of it. After triggering a contemporary controversy that advocated the abolition of the Gending Sriwijaya dance, this paper came as a critical expression of rejecting the claim. The importance of cultural heritage must be presented as an educational reference because its presence is a form of historical value. The purpose of this writing is the study of Gending Sriwijaya dance which focuses on interpretations of motion that are exhibited by dancers through phenomenology research methods, in order to find the moral values contained in dance movements and seek historical reflection of civil society. Results of discussion: 1) The historicity of the Gending Sriwijaya dance; 2) The moral values contained in the motions of the Gending Sriwijaya dance; 3) Historical reflection values of civil society. Gending Sriwijaya dance should be a logical orientation in the embodiment of dance as a reflection of historical value because its usefulness as a support for future generations of who will contribute to the success of vision of civil society.
PERGESERAN MAKNA FILOSOFIS ALUN-ALUN KOTA BANDUNG PADA ABAD XIX – ABAD XXI
Authors: Falah Miftahul , Yuniadi Agusmanon , Adyawardhina Rina
Published: August 2019

Sebagai kota yang dibangun dengan mempertimbangkan aspek kosmologis, alun-alun merupakan salah satu elemen pembentuk Kota Bandung sejak menjadi pusat pemerintahan Kabupaten Bandung pada 25 September 1810. Alun-alun Kota Bandung mengalami perubahan fungsi, dari titik batas ruang profan dan ruang sakral menjadi ruang terbuka publik sehingga makna filosofisnya mengalami pergeseran. Untuk memahami perubahan tersebut secara kronologis, dilakukan penelitian historis dengan menerapkan metode sejarah yang terdiri dari empat tahap, yaitu heuristik, kritik, interpretasi, dan historiografi. Hasil penelitian menunjukkan bahwa dalam perkembangannya, warga Kota Bandung tidak lagi memandang alun-alun sebagai salah satu elemen penyeimbang antara makrokosmos dan mikrokosmos, melainkan sebagai ruang terbuka publik tempat bersosialisasi seluruh warga kota. Fungsi Alun-alun Kota Bandung menunjukkan perubahan, dari sebuah lapangan terbuka dengan fungsi administratif kota tradisional hingga menjadi sebuah taman kota yang menjadi destinasi wisata di pusat kota sehingga memperlihatkan fungsi sosial-ekonomi.As a city that was built which takes the cosmological aspect into consideration, the square is one of the elements that formed the city of Bandung since becoming the capital of Bandung Regency on September 25, 1810. Its changing functions, which were traditionally perceived as a boundary of profane and sacred space into modern public open space, reflected a shifting in philosophical meaning. To understand the changes chronologically, this paper uses historical method which consists of four stages, namely, heuristics, critique, interpretation, and historiography. The results show that gradually the citizens of Bandung no longer look at the city square as one of the elements of the balance between the macrocosm and microcosm, but rather as a place for community gatherings. Its function changes from an open field with the administrative role of the traditional city into a city park that became a tourist destination in the city centre with socio-economic functions.
“ELMU ANYAR” SINGKRETISME DALAM PENYEBARAN AGAMA KRISTEN DI JAWA BARAT PADA ABAD KE-19 DAN AWAL ABAD KE- 20
Authors: Mulyadi Raden Muhammad
Published: August 2019

Penyebaran Kristen di Jawa Barat menurut para tokoh penyebarnya pada masa Hindia Belanda dapat dikatakan terlambat apabila dibandingkan penyebarannya di wilayah lain di Indonesia. Tulisan ini menjelaskan sinkretisme dalam sejarah penyebaran agama Kristen di Jawa Barat. Metode penelitian yang digunakan dalam tulisan ini adalah metode sejarah yang terdiri dari heuristik, kritik, interpretasi dan historiografi. Hasil penelitian memperlihatkan bahwa masyarakat Sunda menjadi tujuan penyebaran agama Kristen sejak pertengahan abad ke-19. Penyebaran agama Kristen tersebut dilakukan ke wilayah-wilayah yang letaknya terpencil dengan membentuk komunitas-komunitas Kristen. Penyebaran agama tersebut salah satunya dilakukan dengan memperkenalkannya sebagai “elmu anyar” (ilmu baru). Penyebaran agama Kristen dilakukan secara perlahan, salah satunya adalah dengan melakukan penyebaran secara tersembunyi. Pada awalnya penyebaran Kristen dilakukan dengan cara melakukan dialog-dialog dalam upaya mencari “elmu” kehidupan yang diwarnai dengan ajaran-ajaran Kristen tanpa menyebutkan bahwa elmu tersebut merupakan ajaran agama Kristen.    The spread of Christianity in West Java during the Dutch East Indies period according to its missionaries can be considered quite late when compared to other regions in Indonesia. This paper examines syncretism in the history of the spread of Christianity in West Java. The research method used in this paper is a historical method consisting of heuristics, criticism, interpretation and historiography. The results of the study show that the Sundanese people became the target of Christian missionaries since the mid-nineteenth century. Missionaries’ activities were sent out to regions that were located in remote areas by forming many Christian communities. One of the methods used for evangelizing was by introducing it as "elmu anyar" (new knowledge). It was carried out slowly and secretly by conducting dialogues as an effort to search secret knowledge of life colored by Christian teachings without mentioning its origin.
Peran Ketua Mahkamah Konstitusi dalam Memengaruhi Putusan Mahkamah Konstitusi
Authors: Hsb Ali Marwan
Published: August 2019

Ketidakpercayaan pencari keadilan untuk mengajukan permohonan pengujian undang-undang ke Mahkamah Konstitusi tentu menjadi satu masalah dalam proses pencarian keadilan di Indonesia. Hanya dikarenakan Ketua Mahkamah Konstitusi diduga melakukan lobi-lobi dengan Komisi III Dewan Perwakilan Rakyat, kemudian dianggap Mahkamah Konstitusi tidak lagi objektif dalam memutuskan suatu perkara. Dalam tulisan ini kemudian akan dilihat bagaimana sebenarnya keberadaan atau peran Ketua Mahkamah Konstitusi dalam memengaruhi putusan Mahkamah Konstitusi. Dalam proses pengambilan keputusan pada Rapat Permusyawaratan Hakim, Ketua tidak dapat mendikte dan memaksakan isi putusan sebagaimana yang diinginkannya kepada hakim konstitusi lain. Hal ini jelas terlihat dalam beberapa putusan Mahkamah Konstitusi, dimana seorang Ketua Mahkamah Konstitusi kalah dalam perdebatan dalam Rapat Permusyawaratan Hakim dan mengajukan dissenting opinion. Dari hal tersebut juga dapat dilihat bahwa Ketua Mahkamah Konstitusi tidak bisa memengaruhi putusan Mahkamah Konstitusi dengan kedudukannya, melainkan dengan argumentasinya terhadap suatu perkara. Oleh karena itu, untuk menghindari adanya dugaan-dugaan lobi antara hakim konstitusi termasuk Ketua Mahkamah Konstitusi dengan lembaga negara pengusul disarankan agar proses perpanjangan masa jabatan hakim konstitusi tidak lagi dilakukan fit and proper test.
GESTÃO DA QUALIDADE E DA PRODUÇÃO: INTEGRAÇÃO DE TÉCNICAS AVANÇADAS E SUAS APLICABILIDADES NA INDÚSTRIA MODERNA.
Authors: Raposo Cláudio Filipe Lima , da SIlva Marina Lourenço
Published: August 2019

E A preocupação com a Produção no século XXI é destaque em um mundo cada vez globalizado e as necessidades humanas cada vez mais complexas e insaciáveis. O presente trabalho busca uma abordagem sobre as técnicas Lean Manufacturing, Six Sigma e World Class Manufacturing (WCM) destacando sua importância para o mercado industrial, a busca do conhecimento dessas ferramentas no século XXI. A integração do dessas ferramentas tende a elevar plenamente a qualidade do produto, no processo de produção, na redução de diversos custos, na conservação do ambiente de trabalho e no desenvolvimento de uma indústria mais fluida.
TRAINING WRITING NONFICIAL STORIES IN STUDENTS OF THE PGSD STUDY PROGRAM WIDYA DHARMA KLATEN UNIVERSITY
Authors: Sakti Bayu Purbha
Published: August 2019

Widya Dharma University Primary School Teacher Education (PGSD) Study Program students are expected to have insight and knowledge in writing nonfiction stories or real news. The purpose of this service activity program is to train prospective elementary school teacher students to be able to write nonfiction stories or real news. The method used in this service is the provision of training with lecture, discussion, and question and answer methods. The results obtained in the training of writing nonfiction stories are the participants' interest and the urgency of the news. The trainees writing nonfiction stories have an interest in being interested in writing nonfiction stories or real news because it will be useful information in the community. The urgency of real news must be delivered because real news will provide truth that must be understood by all parties including elementary school children.
Contextual Cell Death in Immunity: Selecting a Winning Response
Authors: Herbert Alan
Published: August 2019

Winning the game “Rock, Scissors, Paper” depends on what others do. There is no guarantee that one choice will always win. Does the immune system use the same intransitive logic, tapping receptor-ligand pairs, called clicks, to kill off unwanted responses, exploiting contextual cell death and lineage plasticity to select winners?
Mengkritisi Pemberlakuan Teori Fiksi Hukum
Authors: Hsb Ali Marwan
Published: August 2019

Dalam sistem pembentukan peraturan perundang-undangan di Indonesia, masih kita temui adanya pemberlakuan teori fiksi hukum.Dimana semua orang dianggap tahu hukum apabila sudah diundangkan dalam lembaran resmi dan ketidaktahuan seseorang atas hukum atau peraturan perundang-undangan yang berlaku tidak membebaskan seseorang itu dari tuntutan hukum (igronantia iuris neminem excusat).Hal ini tentu bertentangan dengan nilai-nilai keadilan yang ada di masyarakat.Diperlukan upaya-upaya untuk mengikis keberlakuan teori fiksi hukum ini.Hal inilah yang menjadi pokok permasalahan dalam tulisan ini.Metode penelitian yang digunakan adalah metode penelitian hukum normatif dan untuk memperoleh data digunakan studi perundang-undangan dan telaah kepustakaan.Dari hasil penelitian memperlihatkan bahwa teori fiksi hukum masih diberlakukan dalam sistem peraturan perundang-undangan di Indonesia. Untuk mengikis keberlakuan teori fiksi hukum dapat dilakukan 2 (dua) upaya baik dari pemerintah maupun dari masyarakat, yaitu publikasi oleh lembaga pembentuk peraturan perundang-undangan dan partisipasi aktif dari masyarakat dalam proses pembentukan peraturan perundang-undangan tersebut.
Búsqueda y recuperación de la literatura científica
Authors: Martínez-Ezquerro José Darío , Rendón-Macías Mario Enrique
Published: August 2019

En sentido amplio, investigar involucra cualquier búsqueda y recopilación sistemática y pertinente de datos, información y hechos, así como su análisis, para aumentar el conocimiento sobre un tema determinado. Un aspecto fundamental durante el proceso de investigación involucra el conocimiento y dominio práctico de la literatura científica (alfabetización informacional). En este capítulo se presentan las principales bases de datos de la literatura académica que contienen datos relevantes a las áreas de la salud y biomédicas. Además, presentamos estrategias de búsqueda bibliográfica para facilitar su adquisición cotidiana, sistemática, reproducible y precisa, que nos permita realizar investigaciones profundas y generar nuevo conocimiento. Martínez-Ezquerro JD, Rendón-Macías ME (2021) “Búsqueda y recuperación de la literatura científica” en: (coord. Miguel Ángel Villasís-Keever, Mario Enrique Rendón-Macías) Guía práctica para la elaboración de protocolos de investigación clínica (24-39). Ciudad de México: Sociedad Mexicana de Pediatría, 250p. (ISBN 978-607-7545-07-1), doi: https://doi.org/10.31219/osf.io/y4nep