bluuebunny/crossref_metadata_2025 huggingface dataset:
Splenic rupture post colonoscopy requiring splenectomy
Authors: Nguyen Phi , Pretorius Frans
Published: September 2024

Colonoscopy is a safe procedure performed routinely worldwide. Splenic rupture is a rare complication of colonoscopy with less than 100 case reports since 1974. We report a case of splenic rupture post colonoscopy requiring splenectomy, with a focus on the analysis of risk, investigation and treatment.  A 60-year-old patient underwent a colonoscopy with polypectomy after a positive faecal occult blood test. After 19 hours, the patient experienced abdominal pain and dizziness. A computed tomography showed a splenic rupture and abdominopelvic hemoperitoneum. An urgent splenectomy was successfully performed. Physicians should have greater awareness of the possibility of splenic rupture following coloscopy to avoid delay in diagnosis and treatment for this life-threatening complication.
ABOIO: EVOCAÇÃO AO SERTÃO
Authors: Guedes Heverton Da Silva
Published: September 2024

ResumoConjugando análise fílmica e revisão bibliográfica, esta pesquisa se debruça sobre Aboio (2005), de Marília Rocha, a fim de analisar como o filme, ao partir de uma perspectiva sertaneja subjetiva(da) (Lins; Mesquita, 2008), propõe uma paisagem outra aos sertões presentes nas narrativas predominantes (Albuquerque Jr., 2014; Moreira, 2018). Ancorando-se na mesma estrutura simbólica em que se divide o longa, o “boi”, o “homem” e o “infinito”, discutimos a comunhão entre sujeito, bicho e natureza (Lima, 2014; Welle, 2016), e intuímos, de antemão, que a evocação que se ouve e que se vê aqui é, antes de tudo, a um sertão-sensível.Palavras-chave: Sertão; subjetividade; Aboio.
OCULTO: REFLEXÕES DE UM PROCESSO CRIATIVO ENTRE TEATRO E AUDIOVISUAL
Authors: Dalmagro Marilia Cauz
Published: September 2024

ResumoO seguinte trabalho propõe a análise do processo criativo, a partir da execução de um projeto audiovisual autoral. O objeto de pesquisa em questão é o curta-metragem Oculto, realizado para o estágio em Interpretação Teatral no curso de Teatro da Universidade Federal do Rio Grande do Sul, durante a pandemia. Ao longo dos capítulos, discorre-se sobre as principais referências que embasaram os ensaios e improvisações, fundamentaram a criação dramaturgia e auxiliaram para a constituição de uma atuação num registro que abarcasse a atmosfera da obra. O filme amalgama aspectos realistas na interpretação e absurdos na dramaturgia, mesclando a linguagem teatral e audiovisual, ambos os campos de ofício da atriz, que discursa sobre as dificuldades e progressos durante o processo.Palavras-chave: Dramaturgia; atuação; teatro; audiovisual.
MATOU O CINEMA E FOI A FAMIILIA: GENEALOGIA PESSOAL ACERCA DE UM PROJETO DE CINEMA EXPERIMENTAL NA AMAZÔNIA PARAENSE
Authors: Moura Mateus Nogueira de Farias
Published: September 2024

ResumoEste artigo é uma reflexão sobre o nascedouro, em 2012, do MATOU O CINEMA E FOI A FAMILIA, projeto audiovisual de realismo experimental, criado e gerido pelo autor do artigo, o realizador e pesquisador Mateus Moura. O artigo tem o intuito de contribuir com o pensamento sobre o cinema experimental na Amazônia paraense no início do século XXI a partir de um texto memorial reflexivo acerca de três obras autorais: Jamcine, Rmxtxtura’s e O meu é especial. Refletindo sobre o cinema-ensaio, o cinema-performance, o remix e a experimentação com mídias digitais, o autor, uma década depois, reflete sobre as escolhas tomadas em sua iniciação artística, o contexto social no qual surgiram as obras e a poética brotada desta relação entre arte, tecnologia e vida.Palavras-chave: MATOU O CINEMA E FOI A FAMILIA; cinema experimental; Amazônia paraense.
ÉDIPO DE NEON: ESTILO E NARRATIVA DO FILME APENAS DEUS PERDOA (ONLY GOD FORGIVES, DIN/FRA, 2013)
Authors: Castelo Sander Cruz
Published: September 2024

ResumoO filme Apenas Deus perdoa (Only God Forgives, DIN/FRA, 2013), de Nicolas Winding Refn, trata, de forma estilizada, de família norte-americana que, mantendo negócios escusos em Bangkok, defronta-se com tenente de polícia obstinado ao tentar vingar um de seus membros. Tendo parcela da crítica apontado dissintonia entre sua forma e conteúdo, defende-se que os problemas da obra são, sobretudo, de verossimilhança. Com esse intuito, decompõe-se e se contrapõe a narrativa e o estilo do filme, de forma a aclarar as suas inconsistências, especialmente, na construção do enredo e dos personagens.Palavras-chave: Filme Apenas Deus perdoa (Only God Forgives, DIN/FRA, 2013); narrativa; estilo.
Resilience and mental state of lung recipients in the context of the COVID-19 pandemic
Authors: Jaworska Izabela , Pudlo Robert , Mierzyńska Anna , Stącel Tomasz , Urlik Maciej , Hrapkowicz Tomasz
Published: September 2024

Wstęp

Transplantacja płuc jest jedyną skuteczną metodą leczenia pacjentów z chorobami tego narządu w końcowym stadium. W trakcie leczenia pacjent może być narażony na działanie licznych stresorów, mających niekorzystny wpływ na jego stan psychiczny, a czynniki te mogą ulegać wzmocnieniu w sytuacji pandemii COVID-19. Celem pracy jest ocena prężności i stanu psychicznego pacjentów po przeszczepieniu płuc w kontekście pandemii COVID-19.

Materiał i metody

Badaniu z zastosowaniem Kwestionariusza ogólnego stanu zdrowia (GHQ-28), Szpitalnej skali lęku i depresji (HADS), Ateńskiej skali bezsenności (AIS) oraz Krótkiej skali prężności zaradczej (BRCS) poddano, w trakcie drugiej fali pandemii COVID-19, 40 pacjentów w okresie odległym po transplantacji płuc, u których przed rozpoczęciem pandemii wykonano badanie kwestionariuszem GHQ-28. Badani w trakcie drugiej fali COVID-19 mieli zapewniony stały, zdalny kontakt z ośrodkiem transplantacyjnym.

Wyniki

Średni wiek pacjentów w grupie badanej wyniósł 51 ± 12 lat. Większość stanowili mężczyźni (57.5%). Stan psychiczny pacjentów w skali GHQ-28 nie uległ pogorszeniu w trakcie pandemii koronawirusa. 70% uczestników charakteryzowało się wysokim poziomem prężności zaradczej, a 12,5% (5 pacjentów) niskim. Zmienne psychologiczne nie były zależne od wieku. Zmienne te nie różniły się istotnie pod względem rodzaju wykonanej transplantacji, płci czy pozostawania w związku.

Wnioski

Druga fala COVID-19 nie wpłynęła negatywnie na stan psychiczny biorców płuc. Uwagi i pogłębienia badań wymaga wysoki odsetek zaburzeń snu u biorców płuc.
Icings in the Uda river basin (Western Transbaikalia): peculiarities of modern distribution and possibilities of use
Authors: Chernykh Vladimir N. , Tsydypov Bair Z. , Sodnomov Bator V. , Ayurzhanaev Alexander A. , Zharnikova Margarita A. , Gurzhapov Bair O. , Garmaev Endon Z.
Published: September 2024

Relevance. The increase in the intensity of icing formation in the territory of the Western Transbaikalia from 2019 to the present due to the beginning of the high-water climatic cycle. The volumes of icings increase annually, cases of flooding of settlements and infrastructure facilities are observed. This makes it advisable to conduct a modern detailed study of the icings using new technologies and approaches. In the Uda River basin, which was selected as the study area, icings have not been studied sufficiently, and there is little information about them in literature. At the same time, they are a valuable resource, since massive ice fields accumulate a significant part of the winter runoff of both surface and groundwater. Therefore, icings can be used for economic purposes as a source of water supply for agricultural production when they melt in the warm season. Aim. To assess the intensity of manifestation of icing formation within the Uda River basin with the identification of general patterns of modern distribution of the icings, the impact of various environmental factors on their dynamics, as well as the possibilities of their utilization. Subjects. Icings formed in the cold season in the Uda River basin in the conditions of dissected mid-mountainous relief and wide distribution of permafrost rocks (permafrost). Methods. Remote and field expeditionary methods of scientific research. Landsat-4-5, Landsat-8, Sentinel-2 space images and Resurs-P data were used as a source of information for remote sensing. Data on icings thickness were obtained using field methods in the course of icings surveys, and local digital terrain models of key sites in the areas of icings development were compiled using UAVs. Data processing was carried out using GIS methods. Results. Current and retrospective maps of icings location were obtained. On the territory with the total area of about 35 thousand km2 up to 3.2 thousand icings are formed in winter depending on the natural and climatic conditions. During low-water climatic cycles, the number of icings decreases by 1.5 times. The large number of icings with their relatively small size is a consequence of the discontinuity of the cryolithozone in the study area. Groundwater icings prevail, where ice fields contain most of their runoff during the cold period of the year. The Uda River basin icings characterize the groundwater reserves of the territory and can be used as sources of water supply for agricultural production in the dry period from April to June, when there is practically no precipitation.
Sorbents based on foamed phosphate glass for collecting petroleum oil products from contaminated soils and water surfaces
Authors: Karapetyan Kirill G. , Dorosh Inna V. , Zgonnik Pyotr V. , Korshunov Alexander D. , Perina Anastasiya I.
Published: September 2024

Relevance. The need to clean from pollution soils and water areas contaminated with oil and chemical industry wastes. Physico-chemical methods are one of the effective ways of cleaning, provided that sorbents are applied in time to collect contaminants from the surface of water areas and landscapes. Sorption is the most efficient and cost-effective method for relatively small scale pollution. Despite the variety of existing sorbents, in most cases when cleaning up accidental spills, first of all, economic benefits and oil capacity value of the sorbent are guided. However, such essential criteria as: 1) main purpose (type of polluted surface and nature of pollution); 2) physical and chemical properties, including structural characteristics and acid-base adsorption centers; 3) peculiarities of oil or other pollutants adsorption. Taking into account these factors, it is possible to develop and improve the formulation of sorbents based on phosphate foams. Introduction of various modifying additives into material composition is likely to expand their field of application. Aim. Development of formulation and technological features of obtaining new phosphate sorbents in relation to their intended purpose: for collecting oil and petroleum product spills from soil or water surfaces. Methods. Gravimetric, microscopic spectroscopic, statistical and comparative methods. Results and conclusions. The authors have compared sorbents no. 1 and 2 in terms of physical and chemical properties, morphology and cleaning efficiency. Based on our laboratory studies, we concluded that sorbent no. 1 is better suited for sorption from aqueous surfaces and sorbent no. 2 is better suited for soil cleaning. Both sorbents have the potential to improve their technological properties. This allows refining the formulation of these materials with further testing in laboratory and field conditions, for example, at oil spill sites. For this purpose, it is possible to change the material composition using a different foaming agent, applying modifying additives and varying the temperature mode of firing. Development of new compositions and methods of sorbent foaming will make it possible to select optimal characteristics for each type of contamination. The author proposed as well to create phosphate biosorbent obtained by immobilization of fungi and bacteria on the surface of highly porous carrier. In this case, after sorption of pollution, adsorbed substances will undergo biodegradation with the formation of safe products, and the sorbent will perform the role of fertilizer.
Feasibility Analysis of Geography Textbooks for Class X Semester 2 Hydrosphere Material
Authors: Santi Intan Prama , Angriani Parida , Hastuti Karunia Puji , Adyatma Sidharta , Aristin Nevy Farista
Published: September 2024

A good textbook must be by the applicable curriculum. The subject matter presented in the textbook must be by the correct concept. However, many textbooks on the market still present wrong concepts. Conceptual errors are permanent in students' thinking, making them difficult to change. Assessment of geography textbooks needs to be carried out to determine the conformity of the textbook content with the quality standards determined by the Curriculum, Standards, and Educational Assessment Agency (BSKAP). Assessment standards include content, language, presentation, and design standards. The object of research is the geography textbook published by Erlangga, the Merdeka Curriculum edition. The material analyzed is the hydrosphere material presented in class X semester 2. This research uses descriptive content analysis techniques, using a quantitative approach. The data obtained is analyzed by scoring each component item, calculating percentages, determining eligibility criteria, and describing the assessment results. Based on the overall assessment results, the percentage was 81%. The results of this assessment are included in the appropriate criteria. However, several suggestions are given by the teacher, so that the author can consider them in revising or improving the book.
Kajian Learning Obstacle pada Topik Aljabar ditinjau dari Literasi Matematis oleh PISA 2021
Authors: Hidayah Yumna , Sudihartinih Eyus , Sumiaty Encum
Published: September 2024

The purpose of this study is to determine the type of Learning Obstacle (LO) on the topic of Algebra in terms of Mathematical Literacy by PISA 2021. The method used in this research is a qualitative method using a didactical design research framework that focuses on learning obstacles. The instrument used in studying learning obstacles was designed based on the mathematical literacy of PISA 2021. The participants of this study came from the city of Cirebon, which consisted of four junior high school students in class IX, one high school student in class X, and two high school students in class XI. Data were collected through written tests, interviews, and observations. The results of this study are four types of learning obstacles, namely related to difficulties in converting story questions into mathematical modeling, lack of mastery of the application of algebra in the form of story questions, difficulties in converting story questions into geometric models and ignorance and confusion about what to do in completing test instruments which is given.
Augmented Reality (AR) pada Geogebra 3D untuk Menghasilkan Hypothetical Learning Trajectory Dalam Pembelajaran STEM Materi Jarak Dimensi Tiga Kelas XII SMA
Authors: Aditya Pandu , Ilma Indra Putri Ratu , Susanti Ely , Aisyah Nyimas
Published: September 2024

Penelitian ini bertujuan untuk menghasilkan dugaan lintasan belajar (Hypothetical Learning Trajectory) yang dapat membantu siswa memahami konsep jarak dimensi tiga menggunakan software Geogebra 3D. Penelitian ini menggunakan metode design research tipe validation study. Pendekatan STEM dengan konteks sains. Subjek penelitian adalah siswa Kelas XII SMA Sriwijaya Negara. Pengumpulan data dilakukan melalui observasi, membuat rekaman video tentang aktivitas kerja kelompok, mengumpulkan hasil kerja siswa, memberikan tes awal dan tes akhir, dan mewawancarai siswa. Data dianalisis secara restropektif. Hasil penelitian menunjukkan bahwa lintasan belajar yang diperoleh dapat membantu siswa dalam memahami konsep jarak dimensi tiga, yaitu memahami konsep jarak titik ke titik sebagai langkah awal pemahaman konsep phytagoras, menemukan makna dari jarak titik ke garis dengan proyeksi berbantu software Geogebra 3D, membuat sketsa yang memuat di dalamnya posisi titik, garis, dan bidang berbantu software Geogebra 3D. Penggunaan fitur Augmented Reality (AR) yang terdapat pada software Geogebra 3D dalam pembelajaran jarak dimensi tiga dengan pendekatan STEM dapat membantu siswa memahami konsep jarak dimensi tiga serta dapat membuat siswa lebih aktif dalam pembelajaran di kelas.
Pengembangan E-Modul Berbantuan Flip Builder Berbasis Etnomatematika Budaya Islam Lokal Kudus Pada Materi Matematika Kelas VII
Authors: Putra Galih Tsaniya , Haqiqi Arghob Khofya
Published: September 2024

Penelitian ini bertujuan untuk mengembangkan produk e-modul (electronic module) matematika berbantuan flip builder berbasis etnomatematika budaya Islam lokal Kudus pada materi matematika kelas VII yang valid dan menarik. Bahan ajar matematika yang berbasis etnomatematika budaya Islam lokal Kudus dan terintegrasi nilai keislaman akan lebih menarik bagi siswa. Hal ini dikarenakan dengan adanya etnomatematika siswa dapat belajar matematika melalui budaya sekaligus mengenalkan budaya lokal setempat kepada siswa. Sedangkan integrasi nilai keislaman akan mampu menumbuhkan rasa keimanan dan ketakwaan siswa. Jenis penelitian yang digunakan adalah penelitian pengembangan (Research and Development) dengan menggunakan model ADDIE (Analysis, Design, Development, Implementation, dan Evaluation). Instrumen dalam penelitian ini adalah lembar angket validasi dan angket respon kemenarikan peserta didik terhadap produk e-modul. Hasil penelitian menunjukkan bahwa ahli materi memperolehan nilai rata-rata 3,43, ahli konten islami 3,47, dan ahli media 3,4. Ketiga hasil validasi tersebut telah memenuhi kriteria “Valid”. Sedangkan uji respon kemenarikan dilakukan dua kali pengujian yakni uji skala kecil yang memperoleh nilai rata-rata 3,39 dan uji skala besar 3,46. Kedua hasil uji tersebut telah memenuhi kriteria “Sangat Menarik”. Berdasarkan hasil tersebut, maka dapat disimpulkan bahwa produk e-modul matematika ini valid dan menarik, sehingga dapat digunakan dalam pembelajaran matematika.
Pengaruh model Problem Based Learning terhadap kemampuan berpikir kreatif matematis berdasarkan self esteem peserta didik
Authors: Sari Indah Wulan , Kesumawati Nila , Sari Eka Fitri Puspa
Published: September 2024

Penelitian ini bertujuan untuk mengetahui pengaruh model problem based learning     terhadap kemampuan berpikir kreatif berdasarkan self esteem peserta didik, untuk   mengetahui perbedaan krmampuan berpikir kreatif berdasarkan self esteem, dan untuk mengetahui interaksi antara model pembelajaran dan self esteem terhadap kemampuan berpikir kreatif peserta didik. Metode penelitian ini adalah quasi eksperimen. Populasi pada penelitian ini adalah seluruh kelas X IPA SMA di OKU. Teknik pengambilan sampel yang digunakan yaitu cluster random sampling sehingga terpilih sampel penelitian yaitu peserta didik kelas X IPA 1 sebagai kelas eksperimen dan X IPA 2 sebagai kelas kontrol. Teknik pengumpulan data yang digunakan dalam penelitian ini meliputi tes dan angket. Teknik analisis data yang digunakan adalah uji ANOVA dua jalur. Berdasarkan hasil analisis data diperoleh kesimpulan bahwa: 1) terdapat pengaruh model problem based learning terhadap kemampuan berpikir kreatif peserta didik; 2) terdapat perbedaan kemampuan berpikir kreatif berdasarkan self esteem (tinggi, sedang, rendah) peserta didik; 3) tidak terdapat interaksi antara model pembelajaran dan self esteem terhadap kemampuan berpikir kreatif peserta didik.
Peningkatan Hasil Belajar Matematika Siswa Melalui Pembelajaran Berdiferensiasi dalam Mewujudkan Merdeka Belajar
Authors: Muslimin Muslimin , Hirza Bonita , Nery Rieno Septra , Yuliani Refi Elfira , Heru Heru , Supriadi Agus , Desvitasari Tria , Khairani Neneng
Published: September 2024

This research is motivated by the not yet optimal application of differentiated learning where teachers have not accommodated students' learning needs, in the form of learning readiness, learning interest and student learning profile (style). This study aims to improve student learning activities and outcomes. Data collection techniques using instruments: (1) student activity observation sheets, and (2) learning achievement tests. Data were analyzed with descriptive statistical analysis and descriptive analysis. The results showed that: The average percentage of completeness of student learning outcomes in cycle I was 92%, increasing to 96% in cycle II. While the percentage of student learning activities in cycle I reached 90.25%, an increase of 92% in cycle II. From the results of the study it can be concluded that the application of differentiated learning through the Problem Based Learning learning model can optimize student learning activities and outcomes.
Effects of In Vivo / In Vitro Melatonin Application on the Duodenum in Rats with Experimental Hyperthyroidism
Authors: Şentürk Esra , Çelebi Fikret
Published: September 2024

The aim of this study was to investigate the effects of melatonin on the intestinal motility of hyperthyroidism rats. Therefore, we determined in vivo and in vitro effects of melatonin on duodenal tissue in experimental hyperthyroid rats. 34 Wistar-Albino male rats were fed with physiological conditions, and then euthanized by cervical dislocation. The experimental animals, Group 1: Control group (n=5), Group 1B: Melatonin group in vitro (n=5), Group 1C: Melatonin group in vivo (n=6), Group 2: 2A: Hypertension group (n=6), 2B: Group 2: Hyperthyroidi sm in vitro melatonin group (n=6), 2C: Hyperthyroidism in vivo melatonin group (n=6). Acetylcholine (ACh, 10-7, 10-6, 10-5, 10-4, 10-3, 10-2 M), potassium chloride (KCl, 20, 40, 60, 80, 100 mM) at the end of the incubation period different doses were given to the bathing environment. In in vitro melatonin groups, the determined submaximal doses (ACh 10-4 M, KCl 60 mM) and melatonin at different doses (Mel 10-10, 10-9, 10-8, 10-7, 10-6, 10-5 and 10-4 M) were applied. It was determined that the contraction responses of the isolated duodenal tissues induced by KCl and ACh increased significantly (p
The role of assistant psychologists working in crisis resolution and home treatment teams
Authors: Jones-Webster Summer , Williams Aimee , Farmer Bobby , Cox Siobhan , Thomas Nicola , Leonard Eleanor
Published: September 2024

A service evaluation was conducted to explore staff perception of the role of assistant psychologists (APs) working in a Crisis Resolution and Home Treatment Team (CRHTT). Four APs were employed on a pilot scheme and embedded in four CRHTTs across Hywel Dda University Health Board (HDUHB).
Using a mixed-methods survey, data were collected from staff working with these CRHTTs (N = 26). Quantitative results reported that the participants perceived the contribution of the AP as ‘very valuable’ to both the team and its patients. Qualitative results identified
two overarching themes (Additional Value and Additional Expectations) and five themes (with subthemes): (1) A Stepping Stone; (2) A Different Perspective; (3) More is Needed; (4) Clarifying the Remit; and (5) The Impact on Discharge. Integrative
analysis indicated that there is a need to improve staff understanding of the role and its remit. Further evaluation and research is needed to ensure greater understanding and clarification of the role.
Knee Pain and Quality of Life among the Elderly
Authors: Melati Akilla Nathania , Nugraheni Nuniek , Djuari Lilik , Yulianti Erikavitri , Romadhon Pradana Zaky
Published: September 2024

Background: The aging process can lead to knee pain in the elderly, which negatively impacts their quality of life by decreasing their physical functioning and potentially affecting their psychological well-being over time. This study aimed to determine the association between knee pain and the quality of life of the elderly.
Methods: This analytical study involved elderly patients aged 60 years and over who presented with complaints of knee pain at the Geriatric Outpatient Clinic of Universitas Airlangga Hospital, Surabaya, Indonesia, from September 2022 to March 2023. The participants were selected by consecutive sampling until a total of 50 samples were collected using the interview method. The independent variable was knee pain, while the dependent variable was quality of life. The instruments used were the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) to measure knee pain and the Barthel Index for Activities of Daily Living (ADL) to assess the quality of life. The data were analyzed using Spearman's rho, with p<0.01 indicating a significant correlation.
Results: The majority of the elderly were female (54%) and fell within the age group of 66–70 years. The most prevalent complaint was mild knee pain (52%). A total of 50% of the elderly had an independent quality of life. A strong correlation was found between the degree of knee pain and quality of life in the elderly (p=0.000). The correlation coefficient indicated an inverse relationship between the degree of knee pain and quality of life in the elderly.
Conclusion: The findings suggest that the higher the pain degree suffered by the elderly, the lower their quality of life.
 
Highlights:

This study evaluated the factors that influence the quality of life of elderly individuals with knee pain, an issue that has been relatively overlooked in Indonesia.
The results of this study will hopefully assist scholars and stakeholders, enabling them to optimize the quality of life for elderly individuals experiencing knee discomfort.
Hepatocellular Carcinoma with Chronic Hepatitis B and Non-Islet Cell Tumor Hypoglycemia: A Case Report
Authors: Tjahjadi Angela Kimberly , Maimunah Ummi , Loho Imelda Maria
Published: September 2024

Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome manifestation associated with hepatocellular carcinoma (HCC). This report details a case of a 20-year-old woman with HCC linked to untreated chronic hepatitis B. The patient presented with refractory hypoglycemia that was suspected to be NICTH. She also exhibited decreased consciousness with an initial blood glucose reading of 31 mg/dL. After the administration of intravenous dextrose solution, the patient's consciousness improved, yet intermittent hypoglycemic episodes persisted due to insufficient oral intake. The laboratory findings revealed low levels of insulin and C-peptide. The management of the patient included a continuous infusion of 5% dextrose solution, administration of corticosteroids, and adherence to a high-calorie complex carbohydrate diet. Despite presenting with significant right upper abdominal discomfort and weight loss, the patient was diagnosed with HCC at stage B, according to the Barcelona Clinic Liver Cancer (BCLC) Staging System. The stage was determined based on the presence of extensive multifocal lesions, which rendered surgical resection and transarterial chemoembolization (TACE) non-viable. Consequently, palliative treatment using lenvatinib and antiviral therapy with tenofovir were initiated. NICTH involves an increased insulin-like growth factor 2 (IGF-2) precursor processing by tumor cells, leading to heightened peripheral glucose utilization and persistent hypoglycemia. Although tumor resection is the most effective treatment for NICTH, it was not feasible in this case. This report emphasizes the importance of considering NICTH in the differential diagnosis of refractory hypoglycemia for non-diabetic patients. It also underscores the need for parenteral nutrition and corticosteroid therapy to maintain euglycemia.
 
Highlights:

This case report details a rare clinical presentation of non-islet cell tumor hypoglycemia (NICTH) associated with hepatocellular carcinoma (HCC) and chronic hepatitis B in a young patient, adding to the limited documented cases of this paraneoplastic syndrome.
The report provides a thorough clinical description, extensive diagnostic workup, and comprehensive management strategies, offering valuable insights into the complexities and challenges in diagnosing and treating NICTH in HCC patients.
This case emphasizes the critical need for early detection and intervention in HCC, particularly in non-cirrhotic patients with chronic hepatitis B, and highlights the importance of considering paraneoplastic syndromes in the differential diagnosis of refractory hypoglycemia in non-diabetic patients.
Diagnosis and Management of Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus
Authors: Kahdina Mega , Nugroho Cahyo Wibisono
Published: September 2024

Autoimmune hemolytic anemia (AIHA) may indicate the first manifestation of systemic lupus erythematosus (SLE). It is estimated that the incidence of AIHA is around 10% in patients with SLE. The first-line therapy for AIHA is corticosteroids. Nevertheless, a second-line therapy may be considered if an adequate response is not obtained. Transfusion indication in AIHA patients do not differ from other types of anemia. These indications include the degree of hemolysis, the progression of anemia, and clinical symptoms. However, blood transfusion for AIHA patients is challenging due to the limited availability of serologically compatible blood. In addition, AIHA patients who receive transfusions have an increased risk of experiencing hemolytic transfusion reactions. In this paper, we aimed to present a case report on the diagnosis of AIHA in an SLE patient treated with second-line therapy and red blood cell transfusions. The patient was a 49-year-old woman who presented with the main complaint of swelling in both legs. According to the medical history, the patient experienced petechia, abdominal distension, body weakness, and weight gain. No reports of joint pain, diarrhea, constipation, fever, shortness of breath, or yellowish skin were made. Before being referred to Dr. Soetomo General Academic Hospital in Surabaya, Indonesia, the patient experienced high blood pressure and body swelling that were unresponsive to treatment. Once the diagnosis of AIHA was confirmed, the patient was set to receive second-line therapy and red blood cell transfusions. At the conclusion of the therapy, the patient exhibited favorable outcomes.
 
Highlights:

This paper presents the management of autoimmune hemolytic anemia in systemic lupus erythematosus, which has been understudied in Indonesia.
This paper provides additional evidence regarding the indications and outcomes of red blood cell transfusion in a case of autoimmune hemolytic anemia.
Comorbid Diseases and Outcomes of Critically Ill COVID-19 Patients Admitted to an Indonesian Intensive Care Unit from May to October 2021
Authors: Siahaan Katrin Wilentina , Somia I Ketut Agus , Utama I Made Susila , Dian Ni Made Dewi , Gayatri Anak Agung Ayu Yuli , Purnamasidhi Cokorda Agung Wahyu , Merati Ketut Tuti Parwati
Published: September 2024

Background: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2). The spread of COVID-19 has become a worldwide health threat, with 583,038,110 cases and a death toll of 6,416,023. This study attempted to determine the relationship of age, sex, and comorbid diseases with the outcomes of critically ill COVID-19 patients at Prof. Dr. IGNG Ngoerah Central General Hospital, Denpasar, Indonesia.
Methods: This analytic study employed a retrospective approach, analyzing secondary data from medical records using a purposive sampling method. The research included univariate analysis, bivariate analysis using the chi-square test, and multivariate analysis using a general linear model performed with the assistance of IBM SPSS Statistics for Windows, version 23.0 (IBM Corp., Armonk, N.Y., USA). A statistical analysis result with a p-value of less than 0.05 was deemed significant.
Results: A total of 264 critically ill COVID-19 patients were hospitalized in the Intensive Care Unit of Prof. Dr. IGNG Ngoerah Central General Hospital from May to October 2021. Comorbid diseases were present in 215 patients. The comorbid diseases that had the greatest impact on increasing mortality were diabetes mellitus, hypertension, kidney disease, and cardiovascular disease (p=0.000–0.006, 95% CI).
Conclusion: Age and sex do not have any significant relationship with the outcomes of critically ill COVID-19 patients. Meanwhile, comorbid diseases, such as diabetes mellitus, hypertension, and renal and cardiovascular diseases, pose a significant impact on the mortality rate of critically ill COVID-19 patients.
 
Highlights:

This study investigated patients who were critically ill with COVID-19 to determine the relationship between age, sex, comorbidities, and patient outcomes.
The findings of this study may provide additional data on the impact of comorbidities on the severity of COVID-19, which can be valuable to prevent mortality due to the infection.
Trajetória Ocupacional e Sofrimento Psíquico-social de Migrantes Internacionais no Norte e Centro-Oeste do Brasil
Authors: Figueiredo Vanessa Catherina Neumann , Schlindwein Vanderléia de Lurdes Dal Castel , Echeverria Kamilla Sthefanie da Silva Araujo , Santos Vinícius Eduardo Gama dos
Published: September 2024

Este artigo tem como objetivo estabelecer uma comparação entre os resultados de duaspesquisas que investigaram a experiência de sofrimento psíquico-social de migrantesinternacionais em busca de trabalho no Brasil. Para isso são apresentadas as diferentesprivações e vivências no deslocamento, a inserção laboral e as expectativas de trabalho nonorte e no centro-oeste brasileiro, por meio do método comparado de estudo de caso.Realizadas nas cidades de Corumbá e de Porto Velho, as pesquisas foram fundamentadas naPsicodinâmica do Trabalho e se valeram de conceitos da psicossociologia e do enfoqueintercultural na análise das dificuldades vivenciadas para a garantia dos direitos básicos aosmigrantes. As duas pesquisas revelaram a inserção marginal de migrantes no mercado detrabalho brasileiro, impeditivo de reconhecimento e de integração ao novo país. A condiçãoprecária caracterizada pela discriminação apareceu acompanhada dos sentimentos deinsegurança, impotência, tristeza, vergonha, ansiedade e angústia, indicando o desafio aindaexistente da inclusão social e acesso a empregos decentes no país.
Bem-estar espiritual no contexto do trabalho: panorama das publicações internacionais
Authors: Kuhn Nuvea , Lopes Luis Felipe Dias
Published: September 2024

Esta pesquisa objetiva demonstrar um panorama das publicações internacionais que relacionaram o bem-estar espiritual no contexto de trabalho. Para tal, realizou-se uma Revisão Sistemática de Literatura a partir de uma busca nas bases Web of Science (WoS) e Scopus, o que resultou no mapeamento de 678 artigos, e na seleção de 112 estudos. Os resultados foram analisados com o auxílio do Microsoft Excel®, pacote R Bibliometrix, e VOSviewer versão 1.6.18. Os principais resultados indicam que o bem-estar espiritual tem recebido mais atenção ao longo da última década, especialmente no que concerne aos profissionais da saúde. A análise de co-ocorrência de palavras-chave revelou que a liderança espiritual está relacionada ao bem-estar espiritual e que este, por sua vez, influencia positivamente o ambiente organizacional.
On the issue of Christianization of the population of the Taz River Subarctic (by the materials of the burial ground of Num-hibya-siheri VIa)
Authors: Gyurdzhoyan K.G. , Tkachev Al.Al. , Tkachev A.A.
Published: September 2024

In recent decades, there has been a significant increase at the number of studies aimed at the research into archaeological sites dating back to the period of active development of Siberian territories by Russian explorers. The indication of this process is the commenced Christianization of local indigenous population. The study of the burial objects of the Late Medieval and Modern Times allowed assembling representative collections of stauro-graphic materials. The items retrieved during the study of the Num-hibya-siheri VIa burial ground reflect specific features of the use of Christian symbols in the funeral rite. Therefore, this site is considered to be an early Chris-tian monument left behind by indigenous population of the Taz Subarctic, formed under the influence of Christian ideas that spread in the region in the 18th — early 20th century. The Num-hibya-siheri VIa burial ground is located on the right bank of the Num-hibya-siheri creek on the territory of the Mameyev Cape stow, which is 12.5 km south-east of the village of Tazovsky and 2.4 km north-west of the village of Gaz-Sale of the Yamalo-Nenets Autonomous Okrug, the Tyumen Oblast. In 2017–2018, Tazovsky Archaeological Expedition of the Institute of the Problems of Northern Development of the Tyumen Scientific Research Center (Siberian Branch of the Russian Academy of Sciences) uncovered 286 m2 of the site. Within the studied area, nine underground pits were investi-gated, containing the burial of an adult (?) and children (8) aged from newborn infants up to 5- to 7-year-olds. The main components of the funeral rite and inventory testify to the familiarity of the people, who left this burial ground behind, with Christian customs and Christian ritualism. The deceased children are buried in wooden coffins placed inside composite wooden structures, on their backs, with their heads oriented to the western side of the horizon. The interred children are accompanied by an icon pendant with an image of St. Nicholas the Wonder-worker and crosses dedicated to the Great Martyr Barbara and crucified Jesus. The features of the funeral rite and the placement of the articles indicate an initial stage of the Christianization of autochthonous population, combining both Christian and pagan components in the process of burying children. A good preservation of the wooden funerary structures allowed selection of wood samples for dendrochronological (tree-ring) analysis, as a result of which the time interval of the functioning of the Num-hibya-siheri VIa burial ground was determined within the second quarter of the 19th — early 20th century.
Pelatihan Metode Pengajaran Untuk Meningkatkan Partisipasi Orang Tua Selama Pembelajaran Daring
Authors: Ahadiati Lifthya , Habibi Muhammad Mizan , Fatimah Malida
Published: September 2024

Orangtua memainkan peran penting dalam proses tumbuh kembang anak termasuk dalam proses pendidikan yang ditempuh oleh anak. Situasi pandemi yang membuat anak menjalankan proses belajar dari rumah membuat peran orang tua semakin signifikan. Kurangnya keterampilan dalam mendampingi proses belajar daring membuat orang tua sulit untuk menunjukkan sikap pengasuhan yang suportif bagi anak. Pelatihan metode pengajaran yang meliputi metode pembelajaran yang efektif serta pengasuhan suportif bagi anak terbukti mampu secara signifikan meningkatkan keterampilan orang tua dalam mendampingi proses belajar daring yang diselenggarakan dari rumah. Pelatihan disampaikan dalam beberapa sesi mulai dari asesmen awal, pemberian pelatihan dalam bentuk ceramah dan role play, posttest, hingga follow up dalam bentuk focused group discussion dengan guru. Melalui pelatihan tersebut, pemahaman orang tua mengenai metode pembelajaran yang efektif meningkat signfikan sehingga 62% peserta memahami dengan baik metode pembelajaran yang efektif tersebut. Pelatihan ini juga terbukti mampu secara signifikan meningkatkan pemahaman orang tua dalam menerapkan pola asuh yang suportif sehingga keseluruhan peserta memiliki pemahaman yang baik tentang pengasuhan suportif bagi anak. Selanjutnya, sekolah juga dapat mengembangkan metode pembelajaran yang variatif seperti project based learning selama pandemi untuk dapat memudahkan peserta didik dalam memahami materi sekaligus meningkatkan interaksi antara orang tua dengan anak.
Gravity and Riemann Hypothesis
Authors: Shi Jun Ze
Published: September 2024

Theoretical physics addresses the fundamental principles of nature and the mysteries of the universe. In the last century, the theory of relativity challenged people's understanding of time and space, while quantum mechanics revealed various forms of energy. However, the concept of gravity remains elusive. All matter in the universe is composed of energy that can be converted into other forms, yet it is always conserved. However, achieving a state of equilibrium, represented by the equal sign, can be challenging to achieve on both macro and quantum scales. A phenomenon that can transition from one state to infinity is called collision and is essential for understanding natural phenomena and physical processes throughout the universe. In the study of general relativity cannot be three-dimensional problems to gain mathematical inspiration, understand the application of new dimensions. Here, we elucidate the nature of gravity, which inspires the solution of the Riemann hypothesis. Our results show that the conduction mode of dimensional energy is defined by Euler's formula. And a special mode of collision is derived which translates into vibration.
Validation of the Rosenberg Self-Esteem Scale in Military Personnel of the Spanish Army (RSE-JGA)
Authors: Soriano-Sánchez José Gabriel , Sastre-Riba Sylvia
Published: September 2024

Background: Self-esteem is a psychological term that, since its emergence in 1890 with William James, has been widely studied. Furthermore, this construct has been examined in different areas of psychology, including the clinical field, where its relationship with mental health and low levels of depression has been demonstrated. In the realm of positive psychology, its connection to resilience and life satisfaction has also been established. Objective: To evaluate validity based on internal structure from the perspective of Classical Test Theory (CTT) and Item Response Theory (IRT), to obtain evidence of validity based on the relationship with other variables and to estimate the reliability of the Rosenberg Self-Esteem Scale (RSES). Method: To this end, 584 military personnel from the three ranks of the Spanish Army (officers, non-commissioned officers, and professional soldiers and sailors) were evaluated, of which 511 were men (87.70%) and 72 were women (12.30%), with an age range of 18 to 66 years (M = 33.17, SD = 7.38). Results: The results indicate that the unidimensional structure of the RSES shows adequate fit indices (CFI = .94, TLI = .91, SRMR = .05), while the difficulty and discrimination parameters exhibited favorable values. Additionally, an acceptable reliability value was found (ɷ = .81; α = .80). Conclusions: Therefore, it is concluded that the RSE-JGA presents adequate psychometric properties of validity and reliability, making it a useful and relevant instrument for measuring self-esteem in military personnel of the Spanish Army.
Elucidating the Pathophysiological Mechanisms of Alzheimer’s Disease
Authors: Saragea Paula Denisa
Published: September 2024

Alzheimer’s disease (AD), the leading cause of dementia (50-70%), is a multifactorial neurodegenerative disorder characterized by progressive cognitive decline and significant neuropathological changes, including β-amyloid plaques and neurofibrillary tangles. This review synthesizes current understanding of the complex interplays that contribute to the pathogenesis of AD, while exploring the mechanisms underlying the formation of β-amyloid plaques and neurofibrillary tangles, with a focus on the amyloidogenic and non-amyloidogenic pathways, Tau protein hyperphosphorylation, and the resultant neurotoxicity. Furthermore, the study delves into mitochondrial dysfunction and oxidative stress as critical contributors to neuronal degeneration, highlighting the mitochondrial cascade hypothesis and its implications in both early (EOAD) and late-onset AD (LOAD). The study emphasizes the irreversible nature of the disease’s progression, detailing the pathological transformations from the preclinical to the severe stage, where lesions disseminate throughout the entire cortex.
Comprehensive Review of Eutrophication in Freshwater Ecosystems: Causes, Effects, Assessment, and Management Strategies
Authors: Sitote Yabsra Melak , Gebremedhine Michael Girimay
Published: September 2024

This review examines eutrophication in freshwater ecosystems, a widespread environmental issue stemming from excessive nutrient input, largely due to human activities. The study explores the origins, consequences, evaluation techniques, and control methods for eutrophication. Primary causes include agricultural discharge, urban development, and climate shifts. The effects are far-reaching, impacting biodiversity, water quality, and socio-economic factors. The assessment utilizes a combination of chemical, physical, and biological markers, with cutting-edge technologies like remote sensing improving monitoring efforts. Mitigation strategies are diverse, incorporating preventative actions (such as nutrient limitation and land management), corrective measures (including bio-manipulation and chemical applications), and regulatory initiatives (like water quality guidelines and nutrient exchange schemes). While case studies demonstrate successful interventions, they also reveal ongoing challenges, particularly ecosystem unpredictability and climate change influences. The research highlights the promise of emerging technologies, notably machine learning, in enhancing management practices. Knowledge gaps persist, especially regarding eutrophication-biodiversity dynamics in tropical environments and the socio-economic ramifications of interventions. The study emphasizes the importance of flexible, comprehensive approaches that blend scientific insights with practical solutions and strong policy structures to tackle this intricate environmental challenge in an era of climate change.
Importance-Performance Analysis of Factors Affecting the Sustainability and Development of Poultry Farms (Evidence from Broiler Farms in Baghlan Province, Afghanistan)
Authors: Shaiq Muhammad Asef , Naiemi Moienuddin , Razavi Khalil , Asim Hamidi Shir Agha
Published: September 2024

Ensuring adequate food supplies has become a critical issue with a rapidly growing global population and increasing demand for protein-rich foods. In Baghlan province, Afghanistan, many poultry farms have been forced to cease operations due to insufficient infrastructure and resources, leaving a significant gap in meeting the region's growing demand for poultry products. This study aims to identify the key factors affecting the sustainability and development of broiler farms in Baghlan province as perceived by farm owners. The primary research tool was a researcher-developed questionnaire, whose validity and reliability were confirmed. The study population comprised all broiler farm owners in Baghlan Province, from which a sample of 91 was selected using the Morgan table and complete enumeration sampling method. The findings revealed that approximately 54% of respondents expressed moderate satisfaction with their farms. Importance-Performance Analysis (IPA) was conducted to assess the relative importance and performance of various factors affecting the development and sustainability of the farms. The results indicated that having a qualified expert, the farmer's educational level, the poultry house ventilation system, and being a local resident were considered highly important factors for farm success but were underperforming. Based on limited existing research in the region, these findings provide valuable insights for enhancing poultry farm development and food security in Baghlan province and throughout Afghanistan. The study offers specific recommendations for addressing the identified challenges and improving the sustainability of poultry farming in the region.