bluuebunny/crossref_metadata_2025 huggingface dataset:
About the first head of the Department of Economics and Management, Professor Lin Alexander Alekseevich
Authors: Narkevich Igor A. , Orlov Alexander S. , Trofimova Elena  O. , Vorobieva Svetlana A.
Published: December 2023

The essay is dedicated to Alexander Alekseevich Lin, Professor, Doctor of Pharmaceutical Sciences, the first head of the Department of Economics and Management of the St. Petersburg State Chemical and Pharmaceutical Academy. This essay presents his biography, contribution to pharmaceutical science and education, the results of his work, the most important scientific achievements, as well as information about the scientific, educational, methodological and organizational work of the department, which he headed. Alexander Alekseevich was awarded the prize of the Government of St. Petersburg and the certificate of honor of the Ministry of Health of the Russian Federation for outstanding achievements in the field of higher education and healthcare, as well as awarded the medal “100 years of Russian trade unions”. His vivid and significant contribution to educational activities and the sphere of public life will remain for a long time in the memory of colleagues, students and everyone who knew him. In our short essay, we used the materials of the department, archival data, bibliographic and abstract databases.
Constructing a Bicultural Upbringing Environment in Polish-Italian Families
Authors: Wojnarowska Aneta
Published: December 2023

Introduction: The article relates to research in the field of education focusing on family and identity that have gained particular importance in recent years in relation to the increasing number of children brought up in culturally diverse environments and attending Polish kindergartens and schools not only in the territorial border areas. The aim of the article is to show the ways in which Polish-Italian families living in Kraków construct bicultural educational and parenting environments for their children. Research Aim: Research aim was to analyse and interpret the subjective experiences of Polish mothers raising preschool children with partners of Italian nationality. Method: The research project was embedded in a qualitative research orientation, adopting its methodological assumptions. The data was collected during individual, in-depth, semi-structured interviews conducted with 10 women. Results: Following the analysis and interpretation of the women’s narratives, four models of upbringing strategies created by Polish-Italian families were proposed to be distinguished. These are: a culturally engaged family, a cosmopolitan (European) family, a culturally passive family, a family of unfulfilled expectations and aspirations. Conclusion: The aim of presenting the diversity of family educational environment of children in Polish-Italian families living in Kraków is to encourage those directly involved in upbringing and education – i.e. teachers or educational authorities – to reflect on the situation of children brought up in binational families for the proper and meaningful design of educational and didactic processes that would take into account these children’s family and home experiences, as well as their cognitive and personal potential.
Preparation of Foreign Language Graduates to Teach English for Specific Purposes at the Academic Level
Authors: Linkiewicz Patrycja Małgorzata
Published: December 2023

Introduction: Contemporarily it is not enough to be able to use English solely for general purposes. Thus, foreign language teachers have to obtain a great deal of competences, among which some researchers point to the skills and knowledge from the specialist field. Research aim: The objective of the article consists in analysing if foreign language teachers are sufficiently prepared to teach English for Specific Purposes (ESP) to students of higher education institutions. Evidence-based Facts: The graduates of philology are fully unprepared to teach ESP, while graduates of applied linguistics are partially prepared to undertake such tasks. The main problem with teaching ESP lies, however, in the lack of appropriate didactic materials. Thus, foreign language teachers are left with no other choice than to create their own materials, apply creative teaching methods (e.g. presentations prepared by the students), or to search for the materials loosely connected with a given discipline. Summary: The practical solutions to the problem depicted in the article are suggested, and they are as follows: incorporation of “specialist foreign language methodology” into academic curricula, organisation of courses from a specific field for foreign language teachers, researching the scale of the problem, mutual exchange of experience and materials between the teachers, improvement of the hitherto created coursebooks and materials with account taken of the communicative approach towards language learning, creation of specialist coursebooks.
Análisis de diagnóstico epidemiológico del Cuerpo Oficial de Bomberos de Bogotá
Authors: Moncada Rodríguez Luz Marleny , Puentes Espitia William Ricardo , Feo Martínez Cesar Augusto , Mago Ramos Maria Gabriela
Published: December 2023

Este artículo de investigación trata sobre el análisis del diagnóstico epidemiológico del cuerpo oficial de bomberos de la ciudad de Bogotá, ya que la seguridad y salud en el trabajo (SST) es un campo interdisciplinar que engloba la prevención de riesgos laborales inherentes a cada actividad. Una de las profesiones que presenta todo tipo de riesgos y peligros es la profesión de bombero. Específicamente, los miembros del cuerpo oficial de bomberos de la ciudad de Bogotá, ya que estos se encuentran en constante exposición a radiaciones térmicas, peligros de condiciones de seguridad, contacto con sustancias peligrosas debido a actividades de control y extinción de fuego estructural, forestal y vehicular, control de incidentes de materiales peligrosos, ruidos, caídas, además de jornadas extensas de trabajo, esto convierte al cuerpo de bomberos en una de las poblaciones más expuestas a accidentes y enfermedades laborales. Sin embargo, el sistema de gestión seguridad y salud en el trabajo (SG-SST) diseñado para el cuerpo de bomberos de Colombia, se encuentra estructurado sobre el marco legal colombiano para la SST que comprende las profesiones en general, este hecho resulta limitante al momento de plantear un SG-SST que responda a las necesidades de la profesión de bombero, debido a que este carece de normativas específicas para esta profesión. Por lo tanto, en esta investigación se realizó la caracterización de las actividades, los horarios y la relación de ocurrencia entre las enfermedades relacionadas con el trabajo y los factores que determinan su aparición, a partir del reporte de salud obtenido con los exámenes ocupacionales realizados a todo el personal del cuerpo de bomberos, con el fin de determinar las posibles causas de las enfermedades que padecen y establecer mecanismos que mejoren el SST de la entidad.
Análisis estratégico del proceso de accesibilidad y movilidad del centro histórico de la ciudad de Matanzas
Authors: Sánchez-Suárez Yasniel , Sánchez-Castillo Verenice
Published: December 2023

Las ciudades enfocan su desarrollo en la resolución de problemas con respuestas sostenible, y demandan de una gestión gubernamental centrada en su desarrollo y en especial de los centros históricos por su alto valor patrimonial y necesario cuidado, ello en función de las necesidades de calidad de vida, condiciones ambientales y sanidad de espacios. Se realiza un análisis estratégico del proceso de accesibilidad y movilidad del centro histórico de la ciudad de Matanzas. Se desarrolla una investigación de tipo cuantitativa, bajo un enfoque descriptivo con la finalidad de analizar la situación a nivel estratégico del proceso de accesibilidad y movilidad del centro histórico de la ciudad de Matanzas, se propuso un procedimiento integrado por tres etapas y contextualizado a las organizaciones de gestión de patrimonios históricos, se integran procedimientos para la selección de expertos, clasificación de procesos y análisis estratégico. Se conforma el Equipo Plan Maestro con representantes de todas las áreas que intervienen en el proceso, se caracterizó la organización y de la aplicación del análisis DAFO se identificó que la organización se encuentra en cuadrante de supervivencia con medias por cuadrante FO es 1,76, en el FA es 1,92, en DO es 1,48 y en DA es 3,52 lo que llevó a proponer acciones correctivas estratégicas. La gestión del proceso de accesibilidad y movilidad, influye significativamente en la efectividad en la gestión urbana y vial. Además, exige políticas y estrategias de gestión gubernamental enfocadas a resolver de manera creativa los retos relacionados con el desarrollo de la economía de ciudad de forma sostenible. Entre las implicaciones positivas permite realizar análisis de la situación estratégica de la organización a mediano y largo plazo, fijar metas y planificar políticas de prevención de riesgos ante amenazas.
The accuracy of core needle biopsy in determining histological type and Scarf-Bloom-Richardson grade in invasive breast cancer
Authors: Igor Mbessoh Kengne Ulrich , Balde Salif , Ndiaye Mamadou , Mamadou Ndiaye , Sidy Ka , Ahmadou Dem
Published: December 2023

Core needle biopsy provides information not only on the histological diagnosis but also about tumor grade and different prognosis factors for breast cancer. This study was designed to determine the accuracy of percutaneous core needle biopsy (CNB) through comparative analysis of histological diagnosis and SBR tumor grade of invasive breast cancer between CNB and surgical excision specimen (SES).

This was a retrospective cross-sectional study from January 2023 to July 2023. All patients with invasive breast cancer diagnosed by CNB and confirmed by surgical excision specimen (SES) examination were included in the study. Patients who received neoadjuvant chemotherapy were excluded.

One twenty-three patients were assessed. All patients were female. The median age was 45 years (37 – 54). Invasive ductal carcinoma (IDC) was the major histological type of breast cancer (95.1%) followed by invasive lobular carcinoma (ILC) (4.9%). SBR grade 2 tumors accounted for 78.1% of cases. The majority of patients presented with locally advanced stage breast cancer (65.9%) or a metastatic disease (31.7%). Concordance for histological type was substantial (k= 0.79; p<0,001) whereas it was moderate (k= 0.45; p<0,001) for Scarf-Bloom-Richardson grade.

Histological type on CNB correlates almost perfectly with that of the surgical excisional specimen in case of breast cancer. Nevertheless, the agreement of tumor grade between CNB and SES remains moderate, with a significant underestimation and overestimation rates.
Scrape cytology – Diagnostic tool in large intestinal tumors
Authors: Patil Shashirekha , Kulkarni Nagarekha , Manickyam Shanthi , Hulikeri Shridevi S
Published: December 2023

: Gastrointestinal tumors, mainly esophagogastric and colorectal carcinomas constitute one of the major causes of morbidity and mortality worldwide. The early detection and treatment of gastrointestinal tumors has been shown to improve patient's survival significantly. The current study is carried out to know the efficiency of scrape cytology in diagnosis of large intestinal tumors by comparing with histopathological diagnosis

Thirty surgically removed large intestinal tumor specimens were studied. Scrapings were taken from representative areas of each specimen, spread on slides, stained with H/E and reported. The specimens were fixed in 10% formalin, grossed and routine histopathological processing was carried out, followed by staining with H/E, examined and reported. The diagnosis obtained by scrape cytology and histopathology was correlated and analyzed

Total 30 specimens were received and majority of them were of rectal tumors(20%) and sigmund colon tumors(20%), followed by rectosigmoid region tumors (17%). Over all the scrape cytology diagnosis showed concordance for 28 cases with histopathology diagnosis having diagnostic accuracy of 93.3%.

:Scrape cytology is simple, rapid and economically feasible technique and can be useful as an adjunct for frozen section in intraoperative consultation.
Rare pathological lesions of appendix – A case series
Authors: Asok Aneesha , Chandran M Akhil , Jayalakshmy P. S  , Nisha T. G
Published: December 2023

Acute appendicitis is the most common disease of appendix. Here we are introducing 6 rare lesions of appendix from a tertiary care centre North Kerala. These incidental findings reveals the importance of extensive sampling of appendicectomy specimens.
Pleomorphic adenoma with lipometaplasia: Rare histology finding of a common entity
Authors: Deshpande Nikhil Sanjay , Munemane Anil B , Karle Ravindra Raosaheb
Published: December 2023

We report a rare case of a pleomorphic adenoma with lipometaplasia. A 32-year-old woman presented with intraoral swelling over right side of palate. Computed tomography revealed a heterogeneously enhancing right hard palatal mass without bony erosions. Preoperative diagnosis was offered with intraoral fine needle aspiration cytology following which excision was performed. On histopatholgy, final diagnosis of pleomorphic adenoma with lipometaplasia offered. Though rare it must be kept in mind as differential in cases of fat containing salivary gland lesions.
Autosomal dominant polycystic kidney disease coming up with an unusual presentation of renal cell carcinoma on its first encounter
Authors: Masumdar Asma Shoukat , Padmanabhan Anitha , Gadgil Nitin , Padalkar Gargi
Published: December 2023

Autosomal polycystic kidney disease (ADPKD) is a hereditary condition characterized by expanding cysts that destroys the renal parenchyma causing ultimately the renal failure. The role of ADPKD in causing Renal cell carcinoma (RCC) is still under discussion. A 40-year-old male came with fever with chills with history of hematuria, flank pain and weight loss for 2 months. A CT urography showed Bilateral adult polycystic kidney disease and Upper pole of right kidney showing large well-defined lobulated heterogeneously enhancing mass measuring 11x10.5x11.4 cm, most likely renal cell carcinoma. Patient underwent open right radical nephrectomy. On histopathology, diagnosis was given as Papillary Renal cell carcinoma, background kidney showing features of Autosomal polycystic kidney disease. This case report comprehensively described the coexistence of Adult polycystic kidney disease with renal cell carcinoma, which is unique presentation to present with.
Mucoepidermoid carcinoma with Warthin like features- rare case report
Authors: Joshi Shital Samir , Kadam Swati Satish
Published: December 2023

Mucoepidermoid carcinoma with Warthin like features is a deceptive tumour and can be potentially misdiagnosed as a Warthin tumour which is benign, Warthin tumour with mucinous and squamous metaplasia or MEC transformed from Warthin tumour. We are presenting a case of a 25-year-old woman with recurrent solitary mass in the left parotid gland. Microscopically it consists of predominantly cystic areas and focal solid infiltrative tumour with mucinous, intermediate and epidermoid cells having complex architecture in a fibrotic stroma. Extracellular mucin pools seen. Cystic areas are lined by monolayered as well as bilayer epithelium with lymphoid stroma (Warthin like morphology). Occasional mitosis noted. No necrosis and perineural invasion seen. Immunohistochemically, the tumour is positive for P63, P40, CK5/6, EMA, Mucicarmine stain, diffusely positive for CK7. We reached at the final conclusion of low grade MEC, Warthin like features. Even though the cytogenetic studies are confirmatory, we emphasize the role of histomorphology study with IHC and clinical history in identifying this rare variant of MEC with Warthin like features.
Nodular hidradenoma of eyelid – A rare case with cyto-histo corelation
Authors: Mohanty Shushruta , Panda Sujata , Patnaik Samskruti , Sabat Sheetal
Published: December 2023

Nodular hidradenomas is an uncommon benign adnexal tumor that arises as nodules from eccrine sweat glands. Although it can appear at various sites, its occurrence in eyelids is extremely rare. The diagnosis is usually confirmed on histopathology, and the lesion poses a diagnostic challenge for cytopathologist and is rarely diagnosed on fine aspiration needle cytology (FNAC), which prompted us to report. Here we report a rare case of Nodular Hidradenoma in a 50-year male, that was initially diagnosed on FNAC and later confirmed on histopathology and IHC. Thus, our study emphasizes that FNAC can be used as a first line diagnostic modality for nodular lesions of skin.
Joint simplification of various types spatial objects while preserving topological relationships
Authors: Yakimova Olga P. , Murin Dmitriy M. , Gorshkov Vladislav G.
Published: December 2023

Cartographic generalization includes the process of graphically reducing information from reality or larger scaled maps to display only the information that is necessary at a specific scale. After generalization, maps can show the main things and essential characteristics. The scale, use and theme of maps, geographical features of cartographic regions and graphic dimensions of symbols are the main factors affecting cartographic generalization. Geometric simplification is one of the core components of cartographic generalization. The topological relations of spatial features also play an important role in spatial data organization, queries, updates, and quality control. Various map transformations can change the relationships between features, especially since it is common practice to simplify each type of spatial feature independently (first administrative boundaries, then road network, settlements, hydrographic network, etc.). In order to detect the spatial conflicts a refined description of topological relationships is needed. Considering coverings and mesh structures allows us to reduce the more general problem of topological conflict correction to the problem of resolving topological conflicts within a single mesh cell. In this paper, a new simplification algorithm is proposed. Its peculiarity is the joint simplification of a set of spatial objects of different types while preserving their topological relations. The proposed algorithm has a single parameter — the minimum map detail size (usually it is equal to one millimeter in the target map scale). The first step of the algorithm is the construction of a special mesh data structure. On its basis for each spatial object a sequence of cells is formed, to which points of this object belong. If a cell contains points of only one object, its geometric simplification is performed within the bounding cell using the sleeve-fitting algorithm. If a cell contains points of several objects, geometric simplification is performed using a special topology-preserving procedure.
Teoría social y salud
Authors: Castro Roberto
Published: December 2023

El libro que el lector tiene entre sus manos está escrito con una finalidad didáctica, buscando ofrecer una introducción al campo de la sociología médica y que pueda ser útil a ambos tipos de estudiantes, los de ciencias sociales y los de las ciencias de la salud. La idea es ofrecer elementos que ayuden a trascender las determinaciones antes señaladas, tanto las que favorecen la producción de una sociología espontánea, como las que se asocian con la producción de una ciencia social en salud autónoma, pero sin impacto, o con cierto impacto, pero subalterna. Si bien nos queda claro que la superación de tales determinaciones no depende únicamente de un mayor conocimiento de la riqueza existente dentro de la sociología médica, es incuestionable que esta es ciertamente una condición necesaria para impulsar una movilización más iluminadora. [...] Es nuestra intención que la lectura del libro en su conjunto resulte contundente acerca de la riqueza conceptual y analítica de las diversas escuelas de pensamiento sociológico en su aplicación al campo de la salud, así como del rigor y de la vigilancia metodológica requeridos para lograr que este tipo de análisis rinda frutos. Roberto Castro Fragmentos de la Introducción
English-language borrowings as a source of formation of the French youth argot
Authors:   Orel State University named after I. S. Turgenev, Kudryavtseva Natalia A.
Published: December 2023

The article considers the significance of English-language borrowings in the development of the French youth argot which plays a crucial role in the non-format system. Members of the specified social group create a particular subculture trying to separate themselves from the representatives of other society strata by means of a specific sociolect, among other things. Using English words, the younger generation of the French assimilates them to create a subjective communication code with the help of word-formation techniques that operate on various language levels. The purpose of the research is to determine the main specific and non-specific mechanisms for the formation of new argotic units based on lexemes of English origin obtained by the continuous sampling method on the basis of linguo-stylistic (selection of vocabulary incorporated into the works by modern French writers and rap song scripts) and lexicological (analysis of scientific articles and argotographic sources) areas. The paper deals with the structure of modern French youth argot. The work gives the characteristics of the argotic functional features determining the variety of ways of word creation that cause linguistic isolation. The conducted analysis resulted in a classification of convergent models of neologization concerning the phonological, morphological and semantic linguistic levels. The relevance of the study of the modern youth sublanguage is explained by its intensive structural transformation, active replenishment and, in this connection, by the desire to analyze the communication environment of this reference group that has significantly expanded due to the Internet popularization and the variety of messengers, to understand its vocabulary repertoire and culture. For that reason we should note the necessity for further complex research of the processes occurring with the obtained non-conventional English-language lexical units in the speech of modern French youth.
V. P. Kataev’s comedy Time, forward!: The artistic image of the main character in the context of the variants of the work
Authors:   Independent researcher, Khalilov Ruslan O.
Published: December 2023

The article studies the variants of Valentin Kataev’s comedy Time, forward! in order to identify edits that influenced the author’s expression and the reader’s perception of the image of the main character. While researching comedy variants, it was found that the authors interested in Kataev’s work avoided the comedy Time, forward!. In our opinion, knowing about the corrections of the text of the play, Soviet critics, guided by political correctness, did not dare to engage in public polemics and literary-critical discussion around the famous writer. In the post-Soviet period, Kataev’s dramaturgy lost its relevance, did not kindle the interest of specialists. This study was conducted on the material of the comedy editions published during the author’s lifetime. Its relevance is justified by establishing the originality of the image of the main character of the main version of the work, reflecting the characters, emotions and feelings of people of its era. As part of the sample analysis it was found that by making corrections to the climactic scenes of the ending of the 1934 play, the author leaves the plot, the sequence of scenes, the system of images, the general idea of the work unchanged. During the comparison of the variants of the work, the edits made by the author to the two scenes of the finale were revealed. These scenes, connecting with the preceding scene, create a single plot and ideological and emotional node of the climax of the work. The image of the characters and the hero acquire a completely different appearance. With the appearance of comedy in public and up to the present, it has been believed that the image of the main character is a passionate and uncompromising fighter for the communist attitude to work. The edits revealed in the study in the version of the comedy of 1934, without dismissing the hero’s struggle for the result, a high pace in the socialist competition, indicate self-assertion of personality: high morality, friendly feelings. The image of the communist hero, which did not correspond to the literary and political canon, caused acute criticism and was the reason for suppressing the work. The results of the study give ground to consider the version of the play Time, forward! of 1934, a valuable source reflecting the characters, emotions and feelings of the heroes of its time.
Nikolai Zabolotsky and Maria Yudina: On the history of creative communication
Authors:   Saratov State Conservatoire, Kekova Svetlana V. , Izmailov Ruslan R. ,   Saratov State Conservatoire
Published: December 2023

The article discusses the history of the creative dialogue between the great pianist Maria Veniaminovna Yudina and the outstanding poet Nikolay Alekseevich Zabolotsky. The material was not only Yudina’s memories of her joint work with the poet on equirhythmic translations of the collection Schubert’s Songs conceived by the pianist, but also Yudina’s thoughts expressed in various sources about the specific features of Zabolotsky’s work, whose poetry Yudina “ardently” loved. Based on Yudina’s definition of the poet’s work as “liturgical”, the article attempts to decipher this characterization. Poem Forest Lake is used for analysis, Yudina having noted that the person who wrote this poem is already on the threshold of the knowledge of God. In connection with the specific features of Zabolotsky’s poetic thought, bordering on the theological understanding of the world and man and embodied in the figurative matter of the Forest Lake, the article interprets the Gospel revelation about man, revealed in the writings of St. Gregorius Dialogus. “Traces” of the creative collaboration between Yudina and Zabolotsky are found in the 1947 poem Beethoven, which is not only the result of the joint work of Yudina and Zabolotsky on equirhythmic translations, but also the verbal embodiment of Yudina’s interpretation of Beethoven’s music, which she often played during their meetings with Zabolotsky. The article shows the specific character of the creative method of typological exegesis (this term is introduced by L. Levshun for the study of ancient Russian literature), which is used by Zabolotsky in the poems Forest Lake and Beethoven. Its essence lies in the fact that for any phenomenon or event a prototype is found in the Holy Scriptures and, thus, the event is explained, interpreted within the framework of the biblical paradigm. Zabolotsky does not interpret anything, but directs the reader’s feeling to unravel what kind of sacrament occurs in his poetry. Nikolay Zabolotsky in the poem Beethoven embodied Maria Yudina’s idea about music being a “message of revealed truths”, about music, which is the realization of the universal, cosmic liturgy.
Serapion brothers on the pagers of K. A. Fedin’s diaries of 1946–1968
Authors:   K. A. Fedin’s State Museum, Saratov State University, Grigorieva Marya V.
Published: December 2023

K. A. Fedin’s diaries related to the time of the intense activity of the literary community “Serapion brothers” (1921–1924) have not been preserved. Therefore, the material for the studies of the life of the group as well as of its separate members is obtained by the researchers in the epistolary legacy of the writer. The researchers hardly ever refer to the diaries of the later period, apparently believing that Serapion brothers entirely disappeared from the literary life after 1929. However, the Serapion theme still figures on the pages of Fedin’s diaries of the 1948–1968. It is of interest how the already renowned master contemplates the artistic problems which concerned all the “brothers” at the dawn of their writing youth, “general” mentions of the Serapion brothers in the context of the current dwellings on literature and art. Nevertheless, in the diaries of the period in question, certain writers connected by their general past of the “brothers” come to the foreground. Among them, first of all, are Vs. Ivanov, N. Tikhonov, M. Zoshchenko, V. Kaverin, M. Slonimsky, N. Nikitin. Each of them is an object of Fedin’s scrutiny, who responded to all the personal and creative events in the life of the “brothers”. The article presents, among other sources, previously unpublished materials, which provide a means of identifying the role of Serapion brothers on the pages of Fedin’s diaries of 1946–1968. They make it possible to include these references in the context of how the relationships of the writers – the former members of the group – developed, and to determine the degree to which this literary phenomenon influenced Fedin’s life.
The communicative function of olfactory images in the novels of P. Suskind Perfume and T. Salih The Season of Migration to the North
Authors:   Immanuel Kant Baltic Federal University, Almoussa Yara
Published: December 2023

The article deals with the comparison of olfactory images in Patrick Suskind’s novel Perfume and Tayeb Salih’s The Season of Migration to the North in the communication context of Arab and European cultures. The initial theoretical point, based on the existing developments in the field of literary studies and cultural studies, is the idea of olfactory images as an essential component of the poetics of a work of art. The role played by olfactory images in revealing the characters of the two heroes Jean-Baptiste Grenouille and Mustafa Said is considered. Both heroes share similarities: on the one hand, they have a gift, and on the other, they are alienated from society: they feel lonely, their position in the world is that of an outcast. However, for Grenouille, this alienation is due to his personal features, while Mustafa Said’s psychological problems are connected with the colonial past of his homeland, Sudan. With the help of fragrances, both heroes are trying to restore the destroyed communication links – to evoke love to themselves and assert themselves. The article examines the relationship between olfactory images and the image of the homeland of both heroes. In the novel Perfume, the olfactory image of Paris is represented exclusively in a repulsive way. In the novel The Season of migration to the North, smells, by contrast, return the hero to his childhood, help him achieve harmony with himself and with nature. Olfactory images play an important role in revealing the problem of the protagonist’s communication with women. Grenouille artificially creates a fragrance that causes erotic temptation in the people around him. Salih’s novel also shows the connection between olfactory images and the motives of seduction, however, Mustafa Said does not create artificial smells, but uses natural smells to arouse the interest of his potential victims. The article concludes that the communicative functions of olfactory images in both novels are similar, but their differences are determined by the specific features of Arab and European culture.
Uma proposta de experimento em química analítica instrumental: Determinação espectrofotométrica da constante de ionização do vermelho de alizarina em meios micelares
Authors: Mayrink Maria Isabel Cristina Batista , Sperandio Gabriel Henrique , Reis Efraim Lázaro
Published: December 2023

Foram utilizados dois métodos para a determinação da constante de ionização condicional do indicador vermelho de alizarina S em diferentes soluções micelares a 25 oC, em força iônica constante.  O primeiro método utilizado foi a derivação da curva do máximo de absorvância de cada espectro em função do pH das várias soluções. No segundo método utilizou-se a linearização de Handesson-Hasselbach, em que se utiliza também o máximo de absorvância de cada espectro em função do pH das várias soluções. Os resultados dos dois métodos mostram que a constante de ionização deste indicador é influenciada pela presença dos surfactantes neutro Triton X-100, catiônico SDS e aniônico CTAB. As técnicas potenciométrica e espectrofotométrica de uso comum em química analítica instrumental, aliadas a métodos matemáticos, mostraram-se eficientes nas determinações de parâmetros em sistemas em equilíbrio ácido-base.
Effects of Hydrogen-Rich Water on Interleukin-1β, Number of Osteoclasts and Osteoblasts in Streptozotocin-induced Diabetic Rats with Orthodontic Tooth Movement
Authors: Hadi Lina , Hutapea Albert Manggading , Florenly Florenly
Published: December 2023

BACKGROUND: Orthodontic tooth movement (OTM) may increase the risk of treatment-related complications for some diabetes mellitus (DM) patients. Hydrogen-rich water (HRW) has been demonstrated in many studies to reduce oxidative stress and cell damage. This study aimed to examine the levels of interleukin (IL)-1β, blood glucose level, body weight, tooth displacement, and population of osteoclasts and osteoblasts in diabetic rats with OTM.METHODS: Thirty rats (Rattus novergicus) were divided into 6 groups: OTM, HRW, DM, DM+OTM, DM+HRW, and DM+OTM+HRW. DM, DM+OTM, DM+HRW, and DM+OTM+HRW groups were induced with streptozotocin (STZ) after 8 weeks of high-fat diet (HFD) and continued being fed HFD for 4 weeks. OTM, DM+OTM, and DM+OTM+HRW groups were placed on an orthodontic device for the orthodontic treatment. HRW, DM+HRW, and DM+OTM+HRW groups were administered HRW via oral gavage 3 times a day for 4 weeks. At the end of the study, all rats were euthanized and blood samples were collected for IL-1β measurement using enzyme-linked immunosorbent assay (ELISA) kits. Meanwhile, the rats’ maxilla was taken to measure tooth movement, and the number of osteoclast and osteoblast were counted.RESULTS: The highest increase of IL-1β was in the DM+OTM group (140.07±5.14 pg/mL) and the lowest was in the HRW group (92.80±2.89 pg/mL). The average number of osteoblasts were higher in tension sites, while osteoclasts were higher in pressure sites.CONCLUSION: Consumption of HRW in STZ-induced diabetic rats with OTM can reduce IL-1β levels, reduce tooth mobility, and promote bone remodeling.KEYWORDS: diabetes mellitus, hydrogen rich water, interleukin-1β, orthodontic tooth movement, osteoblast, osteoclast
El principio de autonomía progresiva y su impacto en el derecho de las familias: diálogo entre los derechos argentino y español
Authors: Silvina Radcliffe María
Published: December 2023

El artículo analiza el llamado principio de autonomía progresiva, cuya recepción en el ordenamiento jurídico argentino responde al proceso de constitucionalización y convencionalización del derecho privado. Aborda espe­cíficamente el protagonismo que en el presente les es reconocido a niñas-niños y adolescentes en las relaciones parentales. Orientado por la metodología trialista, el presente trabajo concluye con un contrapunto que busca mostrar los aspectos de cercanía y distancia que se observan en la regulación del objeto de estudio en el derecho argentino y en el derecho español, de la mano de precedentes judiciales en ambos países.
El interés negocial como criterio de distribución del riesgo contractual en el derecho romano y su posible utilidad en contratos atípicos como el leasing financiero
Authors: Camacho López María Elisa
Published: December 2023

El presente artículo pretende dilucidar algunas características del interés negocial como criterio para la distribución del riesgo contractual en el derecho romano, a la vez que expone su aplicación actual para resolver contro­versias relacionadas con el riesgo en el contrato de leasing financiero, tomando como ejemplo una sentencia de la Corte Suprema de Justicia de Colombia.
Promieniotwórczość naturalna i antropogeniczna skał Gór Opawskich i ich zachodniego przedpola
Authors: Moska Agnieszka , Malczewski Dariusz
Published: December 2023

Measurements of natural and anthropogenic radioactivity were carried out in characteristic lithologies in the Opava Mountains and their western foreland (SW Poland). In situ measurements were conducted at 13 locations and rock samples from each site were collected for laboratory measurements. The activity concentrations of the naturally occurring radionuclides and fallout of 137Cs were measured using a portable HPGe gamma-ray spectrometry. The ranges of the activity concentrations of 232Th were 5–71 Bq kg−1 in the laboratory and 2–71 Bq kg−1 for the in situ measurements. For 238U, the activity concentrations ranged from 4–52 Bq kg−1 in the laboratory and from 7–48 Bq kg−1 under in situ field conditions, and for 40K, the ranges were 12–1560 Bq kg−1 in the laboratory and 60–1700 Bq kg−1 for in situ measurements. Measured activity concentrations were compared with average activity concentrations of the radionuclides in similar types of rocks from different global localities and with data from the Sudetes available in the literature. Anthropogenic 137Cs was observed at seven locations with deposition from 38 to 6344 Bq m−2. The external gamma-dose rate varied from 10 to 223 nGy h−1, whereas the average gamma-dose rate in Poland is 45,6 nGy h−1. One of the goals of this work was also to determine the correlation between naturally occurring radionuclides. In the investigated rocks, concentrations of 232Th [ppm] and 238U [ppm], K [%] and 232Th [ppm], and K [%] and 238U [ppm] had a strong positive correlation. No significant differences were found between the in situ and laboratory measurements. The maximum absolute difference between the in situ and laboratory measurements was 140 Bq kg−1 for 40K. Key words: Opava Mountains, natural radioactivity, anthropogenic radioactivity, laboratory measurements, in situ measurements, gamma-dose rate
The Right to Be Ill: Refusal Of Medical Treatment v. Public Health In a Democracy
Authors: Schultz David
Published: December 2023

Debates regarding health and health care generally involve questions regarding whether there is a right to -either. But in a democracy do individuals have a right to refuse medical treatment? The 2019 Covid pandemic raised this question as democracies sought to balance individuals with medical mandates such as the wearing of masks or vaccines. This article examines that question asking whether there is a right to be ill and to refuse force medical treatment in the case of infectious diseases that are life threatening. The article will conclude that in most cases competent adults have a right to refuse medical treatment and be ill, yet such a right has to be balanced against a host of factors supporting the preservation of the life of others.
Hate Speech in Times of the COVID-19 Pandemic: The Social Costs and Legal Implications of a Health Crisis
Authors: Peršak Nina
Published: December 2023

In crisis times, such as the recent health crisis brought out by the COVID-19 pandemic, society responds in a myriad of pro-social as well as negative, anti-social ways. The article starts by mentioning some broader social and regulatory responses to the pandemic that provided a backdrop to the studied phenomenon. It then looks explicitly at hate speech, unpacks the three-layered dimensions of its harmful consequences, helping to grasp the magnitude of harm caused by such pandemic-fuelled prejudice-based expression, and inspects the impact of the pandemic on such expression that is largely criminalised in Europe. The article concludes with some thoughts on the implications and lessons for the future.
Ethical Perspective of the Future Development of Law
Authors: Cerar Miro
Published: December 2023

Law, by its very nature, is human and humane. The humanity of law means that law is a product of man and is intended for man. The humaneness of law, however, means that human dignity and well-being must be the fundamental basis of law. Law, therefore, does not exist without a sufficient ethical foundation. The establishment of a state governed by the rule of law, and a legal culture based on it requires a particularly strong anchoring of law in ethical values. The greatest threats to ethics and law are (1) ethical deficits in areas of society on which law (co-)depends, (2) extreme authoritarian and totalitarian regimes, and (3) autonomous artificial intelligence capable of turning away from humans or even turning against and overcoming humans. In the first two cases, the humaneness of law is critically reduced or even extinguished; in the last case, both the humaneness and the humanity of law are extinguished, which is the worst possible scenario. All these dangers must be recognized in time and adequately averted, and regular efforts must be made to preserve the ethical values and the values of the rule of law.
Unilateral laryngeal paresis: features of clinical picture and diagnostic difficulties
Authors:   Saint Petersburg Scientific Research Institute of Ear, Throat, Nose and Speech,  Saint Petersburg, 190013, Russia, Gotovyakhina T. V. , Stepanova Yu. E. ,   Saint Petersburg Scientific Research Institute of Ear, Throat, Nose and Speech,  Saint Petersburg, 190013, Russia, Makhotkina N. N. ,   Saint Petersburg Scientific Research Institute of Ear, Throat, Nose and Speech,  Saint Petersburg, 190013, Russia
Published: December 2023

The article presents the experience of the phoniatric department of the Saint Petersburg Institute of Ear, Throat, Nose, and Speech in the management of patients with unilateral vocal fold paresis. Variants of the clinical picture of the disease that complicate the compensation of the phonatory, respiratory, and protective functions of the larynx have been studied. The most common clinical picture of unilateral laryngeal paresis is the presence of complaints of hoarseness, diplophonia, inspiratory dyspnea during physical activity, aspiration. However, complaints about the voice may be absent, or they may be presented in the form of an aphonia. Patients may not complain of shortness of breath, or inspiratory stridor appears with minimal physical activity, snoring with episodes of apnea, laryngospasm attacks. The article presents cases of rare manifestations of paresis associated with the phenomena of hypotension and hypotrophy of the laryngeal muscles. These include the weakening of the tension of the medial edge of the vocal fold, thinning of the vocal fold, contouring of the vocal process of the arytenoid cartilage, lower location of the paralyzed vocal fold relative to healthy, rotation of the arytenoid cartilage, rotation of the epiglottis, and others. Compensatory mechanisms of phonation are described. Possible difficulties in diagnosing laryngeal paresis based on video laryngoscopy data, including hypomobility of the vocal fold, as well as options for simulating paresis due to neoplasms and post-traumatic changes in the larynx are considered.
Hearing loss when taking cisplatin, depending on the dose
Authors:   Sverzhevky Research Clinical Institute of Otorhinolaryngology, Moscow, 117152, Russia, Nikitkina Ya. Yu. , Kryukov A. I. ,   Sverzhevky Research Clinical Institute of Otorhinolaryngology, Moscow, 117152, Russia, Kunel’skaya N. L. ,   Sverzhevky Research Clinical Institute of Otorhinolaryngology, Moscow, 117152, Russia, Temnov A. A. ,   Moscow Institute of Physics and Technology, Moscow region, Dolgoprudny, 141701, Russia
Published: December 2023

Cisplatin is a cystostatic agent with a ototoxic side effect. Modern chemotherapy protocols aim to maintain high efficiency against malignant tumors with minimal complications. It is known that one of the side effects of the drug is cisplatin-induced sensoneural hearing loss. Our study research hearing loss with the use of cisplatin depending on the total dose of the drug in clinical practice and identifying target cells in the structure of the inner ear in experiment. A total of 117 patients using cisplatin to treat tumors of various locations were studied, among whom hearing loss was revealed in 28% of cases. Hearing loss predominantly affected the high-frequency region above 8000 Hz and depended on the total dose of cisplatin. We carried out the experimental part of the work on BALB/C mice. To model toxic hearing loss, we used 2 cisplatin administration protocols: a single dose of 12 mg per kg intraperitoneally and a dose of 3 mg/kg sequentially for 7 days. After the administration of cisplatin, a decrease in hearing was recorded according to ABR and DPOAE in all animals, which was more prominent among animals with a single dose of the drug. Histological examination of preparations of the cochlea of animals exposed to the toxic effects of cisplatin showed damage to the structures of the spiral ganglion, stria vascularis and outer hair cells. Variety of damage depended on the dose of the drug.
Modern directions of correction of olfactory disorders in clinical practice
Authors:   Samara State Medical University of the Ministry of Health, Samara, 443099, Russia, Vladimirova T. Yu. , Chaplygin S. S. ,   Samara State Medical University of the Ministry of Health, Samara, 443099, Russia, Kurenkov A. V. ,   Samara State Medical University of the Ministry of Health, Samara, 443099, Russia, Berkovich E. N. ,   Samara State Medical University of the Ministry of Health, Samara, 443099, Russia, Blashentsev M. K. ,   Samara State Medical University of the Ministry of Health, Samara, 443099, Russia
Published: December 2023

Introduction. According to statistics, about 20% of the population have olfactory disorders of various etiologies. Among the older age group, the prevalence of the symptom is significantly higher and ranges from 40% to 65%. Olfactory disorders are most often found in diseases of the nose and paranasal sinuses of viral and infectious genesis and traumatic brain injury. There are currently no approved schemes for the correction of olfactory disorders. However, in chronic rhinosinusitis, the role of endonasal surgical interventions, systemic and topical glucocorticoids, and biological targeted therapy has been substantiated. Olfactory training in patients with olfactory dysfunction of various etiologies may be a promising treatment method. Objective. To review olfactory training techniques in general clinical practice. Materials and methods. The search for publications in the PubMed and Web of Science databases for the period from 2009 to 2023 was carried out. Results. Olfactory training is an effective method of treating olfactory dysfunction of various etiologies. The proposed olfactory training schemes involve the use of various essential oils in a standard concentration, while the duration of training can vary from 3 to 8 months. The effect of training is characterized by improved indicators of discrimination and identification of odors. At the same time, the period of restoration of the sense of smell is determined both by the degree of severity of olfactory disorders and their duration and by the age of the patient. Shorter recovery periods of olfaction were observed in patients younger than 40 years, and longer periods, in patients older than 69 years. Discussion. The study of the prospects for the use of olfactory training in the correction of olfactory dysfunction involves the study of the role of polysensory stimulation in increasing their effectiveness. The most optimal is additional stimulation of the visual analyzer by immersing the patient in a virtual scenario.