bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Metode Penerjemahan Subtitle Film Animasi White Snake
Authors: Agusdtine Prissila , Sofyan Rudy , Ayuningtias Niza
Published: November 2022

Terjemahan adalah mentransfer arti atau makna dari satu bahasa ke bahasa lain. Namun makna yang disampaikan tidak boleh melenceng agar terjemahannya dapat dipahami dan berterima. Dalam melakukan kegiatan penerjemahan, sangat penting untuk memperhatikan penggunaan metode penerjemahan karena jika terdapat penggunaan metode penerjemahan yang kurang sesuai maka akan mengakibatkan hasil terjemahan menjadi kurang baik. Penerjemahan dapat dilakukan ke dalam berbagai media dan salah satunya adalah film. Tujuan penelitian ini adalah untuk mendeskripsikan dan menganalisis metode penerjemahan subtitle film animasi White Snake berdasarkan teori yang dikembangkan oleh Peter Newmark . Penelitian ini menerapkan pendekatan kualitatif dengan data berupa kata, frasa, klausa serta kalimat dalam subtitle film animasi White Snake dan metode pengumpulan data menggunakan studi dokumen. Hasil penelitian menunjukkan bahwa dari 186 data yang diteliti terdapat 7 metode penerjemahan Newmark yang diterapkan dalam menerjemahkan film yaitu 4 metode mengacu pada bahasa sumber yang terdiri dari penerjemahan kata-demi-kata 5 (2,68%), penerjemahan harfiah 27 (14,51%), penerjemahan setia 44 (23,65%) dan penerjemahan semantik 41 (22,04%), serta 3 metode mengacu pada bahasa sasaran yang terdiri dari penerjemahan bebas 32 (17,20%), penerjemahan idiomatik 1 (0,53%) dan penerjemahan komunikatif 36 (19,35%). Metode penerjemahan yang paling banyak diterapkan penerjemah dalam menerjemahkan film animasi White Snake adalah penerjemahan setia dengan mempertahankan struktur gramatikal bahasa sumber.
Comparative study on the performance of caryota urens fiber reinforced concrete of different grades along with Digital image processing techniques
Authors: Ramalingam Vijayalakshmi , Sameer Mohamed , Ramalingam Geetha
Published: November 2022

This research work focuses on the effect of natural caryota urens plant fiber as reinforcement on the strength properties of concrete of different grade. Fiber length of 10 mm, 20 mm and 30 mm were added to the concrete mix at an amount of 3% of the binder content. Three different lengths of fibers at fixed volume fraction were added to M30, M40 and M50 grades of concrete. The workability characteristics and mechanical property of twelve different fiber reinforced concrete mixes were investigated.  The effect of fibers on the post cracking behaviour of the concrete specimen was investigated using digital image processing technique and video measuring system images.  Using the developed Linear regression plot, empirical equations were formulated to establish relation between the compressive strength and other mechanical properties of concrete. From the study it can be concluded that the caryota fiber with rich cellulose content contribute to arrest the cracks at the initial stage of loading and prevents major crack plane in the post peak region. Fibers mainly contribute to increase tensile strength of concrete. The effect of fibers is more prominent in M30 mix concrete when compared to M40 and M50 concrete mixes. This research work mainly focuses on the application of natural plant fibers in concrete as reinforcement.
Research on the development status of biomass energy serving the construction of ecological civilization: A case study in Henan province, China
Authors: Li Xueqin , Yang Shuhua , Wang Zhiwei , Huhe Taoli , Yang Yantao , Liu Peng , Huang Sheng , Wu Youqing , Lei Tingzhou
Published: November 2022

The development and utilization of biomass energy based on the thermochemical conversion of crop biomass to produce hydrogen are of great significance for promoting China’s ecological civilization construction, energy revolution, and low-carbon economic development. Henan province is one of the largest agricultural and pasturage provinces in China. Based on the analysis of the status and trends of Henan’s biomass energy (BE) development, this paper summarizes the present status of the construction of ecological civilization (CEC) and the factors restricting its development. Challenges in developing biomass energy are analyzed systematically, and strategies and key technical directions for future biomass energy development are discussed. Finally, the paper presents countermeasures and suggestions for CEC based on the development of BE, which will vigorously promote the development and utilization of BE and the process of CEC. This research provides a reference for the further development of BE and CEC in the future.
Training data augmentations for improving hyperbola recognition in ground penetrating radar B-scan image for tree roots detection
Authors: Li Zeqing , Zhang Xiaowei , Li Haibin , Wang Zepeng , Wen Jian
Published: November 2022

Improving the detection accuracy of hyperbola in B-scan images has been a considerable challenge for ground penetrating radar (GPR) to detect tree roots. In this paper, a method for data enhancement and target detection, both based on deep learning was proposed to identify hyperbolas in GPR B-scan images. First, the authors used a cyclic consistent adversarial network (CycleGAN) to augment the original data. In this procedure, the hyperbolic features of the images were preserved and created a wider variety of training samples. Then, the authors could apply the enhanced dataset to the YOLOv5 detection model to evaluate the effectiveness of their method. Meanwhile, the detection effects of Yolov3, Yolov5, Faster R-CNN, and CenterNet detection models on the enhanced dataset were compared. The results showed that applying the enhanced dataset to the Yolov5 detection model exhibited better detection accuracy compared to other combinations of datasets and detection models. The authors demonstrate that the proposed method increases data diversity and the number of samples, improving the precision and recall of hyperbolic curves. These results provide a new method for tree root localization with important effects.
Research progress on dynamic testing methods of wood shear modulus: A review
Authors: Wang Zheng , Zhang Dong , Wang Zhiheng , Liang Xingyu , Yang Xiaojun , Wang Jun
Published: November 2022

Wood is a non-homogeneous and orthotropic natural polymer material. It is important to test the wood shear modulus and elastic constants accurately and reliably using dynamic methods. Based on the introduction of the advantages of six common methods for dynamic testing of wood shear modulus, such as free plate torsional mode method, free bar torsional vibration method, and Timoshenko beam iterative method, issues associated with the applicability and accuracy of these methods are also pointed out. Recent methods, such as the free square plate torsional mode method and the square plate static torsional strain method, that were developed to dynamically test the shear modulus of wood and wood composite materials, are presented as effective ways to tackle these issues. These new approaches are expected to provide beneficial technical support for using small specimens, overcoming the size effect of specimens, simplifying the testing procedures, improving the test accuracy, and expanding the application range in the dynamic testing of wood shear modulus. These approaches have practical significance in promoting the industrialization and development of structural engineering, furniture and interior decoration, transportation, military, and musical instrument industries.
Bausmės vykdymo atidėjimo nepilnamečiams naujovės ir probleminiai aspektai
Authors: Levon Justyna , Švedas Gintaras
Published: November 2022

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Nepaprastosios padėties įvedimo procedūra: praktika prieš teisinį reguliavimą?
Authors: Masnevaitė Elena , Gedmintaitė Audronė , Vėbraitė Vigita
Published: November 2022

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An update on role of mitochondrial transport in etiopathogenesis & management of various CNS diseases, neurodegenerative diseases, immunometabolic diseases, cancer, viral infections inclusive of COVID 19 disease-a systematic review
Authors: Kaur Kulvinder Kochar , Allahbadia Gautam , Singh Mandeep
Published: November 2022

Mitochondria represent complicated intra cellular organelles which classically have been isolated as the powerhouse of eukaryotic cells secondary to their key part in the bioenergetic metabolism. In more recent decades, the escalation of mitochondrial research has got invoked in researchers that have illustrated that these organelles are much greater than just simple powerhouse of cell, possessing the capacity of other crucial parts like signaling platforms which control cell metabolism, proliferation, and demise besides immunological reactions. In the form of crucial controllers, mitochondria on impairment are implicated, in the etiopathogenesis of a wide variety of metabolic neurodegenerative, immune in addition to neoplastic conditions. Much more recently, greater importance has been given by the researchers with the capacity they possess with regards to. Intercellular transfer which might implicate whole mitochondria, mitochondrial Genome or other mitochondrial constituents. The Intercellular transfer of mitochondria that by definition as horizontal mitochondrial transport can take place in mammalian cells both in vivo, as well as in vitro in addition to both physiological along with pathological situations. Mitochondrial shifting can yield an external mitochondrial source that can restore the normal mitochondrial replacing the mitochondria having undergone impairment, thus resulting in the enhancement of mitochondrial quality, or in case of tumor, altering their functional properties, in addition to chemotherapy responsiveness. Here we have tried to provide a comprehensive review with regards to the biological significance, modes beneath the event, besides their implication in various pathophysiological disorders, emphasizing its treatment potential with regards to diseases where mitochondrial impairment is the primary etiopathogenetic cause of the disease.
The effects of vitamin D on glucose-insulin dynamics: mathematical model and simulation
Authors: Rathee Saloni , Nilam R , Alexander Murray E
Published: November 2022

Background: Maintenance of glucose level for diabetic people is very important and challenging. Many factors seem to affect the level of glucose in our body, out of which vitamin D is found to be one of the most important factors. It inspires us to develop a model that is capable of predicting the effect of vitamin D on glucose-insulin dynamics of human body. Objective: The main objective of the study is to develop a model to capture the effect of vitamin D on the glucose-insulin dynamics of non-diabetic, T2DM and T1DM people. Method: A minimal model previously developed by Bergman is extended to include the effects of vitamin D via parameters. Stability analysis and numerical simulation has been performed on the vitamin D model to analyze the behavior of the model. Comparisons are made to observe the blood glucose and insulin level in non-diabetic, T2DM and T1DM people. Result: The model assess the changes in glucose-insulin dynamics after the induction of different values of vitamin D parameters in their respective range. Conclusion and future work: The vitamin D model captured the glucose-insulin dynamics effectively and should be recommended in our daily routine, especially for the diabetic people. Further, the dosage of vitamin D may be calculated clinically because of the variation in the population and severity of the disease.
Cognições e práticas de professores da educação básica sobre habilidades sociais
Authors: Silva-Imbiriba Andréa , Lellis Irani Lauer , Oliveira Núbia dos Santos
Published: November 2022

Considerando que as cognições docentes são determinantes no desenvolvimento humano, uma vez que exercem forte influência na maneira como caracterizam os fenômenos e, consequentemente, guiam os comportamentos e suas práticas, esta pesquisa objetivou conhecer as cognições e as práticas de professores que atuam na rede pública e privada de ensino na cidade de Santarém-Pará, acerca do construto habilidades sociais. A pesquisa foi realizada com 10 professores, sendo cinco da rede pública e cinco da rede particular atuantes na educação básica. Os dados coletados nas entrevistas foram analisados através da técnica do Discurso do Sujeito Coletivo (DSC). Os resultados mostraram que os professores relacionam suas cognições sobre Habilidades Sociais como necessárias para o desenvolvimento integral do educando. Fica evidenciada, ainda, a necessidade de novas pesquisas na área, com foco em intervenção ou treinamentos de habilidades sociais para este público.
Normatividade como estilo de vida
Authors: Bocca Francisco Verardi
Published: November 2022

Este artigo trata do conceito “normatividade biológica” de Georges Canguilhem, historiador e epistemólogo das ciências da vida, a partir de um cotejo crítico com cientistas e temas cruciais da história das ciências naturais contemporâneas. Pesquisadores como Erwin Schrödinger e François Jacob, entre outros, e temas como ordem, desordem, entropia, neguentropia, catálise e outros. Tal cotejo, além de esclarecer e situar a noção de normatividade, subsidiou uma reflexão a respeito da origem, do regime e do destino da vida, em uma palavra, de sua vitalidade. Como resultado, foi possível sua consideração em uma perspectiva estética. Isso encorajou a aplicação do ponto de vista estético ao fazer humano e às suas consequências sociais e, mais do que isso, encorajou uma expectativa, apenas esboçada, de ação política na condição de desvio e de singularidade, vale dizer, enquanto exercício de um estilo normativo de vida em sociedade.
Sobre fake news
Authors: Fett João , Bonhemberger Marcelo
Published: November 2022

O artigo busca oferecer um quadro conceitual útil para pensar sobre fake news nas trocas testemunhais em ambientes informacionais complexos. Pretende-se mostrar que, em um ambiente social fortemente marcado por interações sociais difusas, no qual fake news afloram ou podem potencialmente aflorar, modificam-se as exigências epistêmicas para a obtenção de racionalidade e conhecimento, sejam elas concebidas de modo internista ou externista. Trata-se, também, de uma revisão integrativa da literatura, com a finalidade de sintetizar os resultados obtidos sobre o tema em questão. Para atingir seus objetivos, o artigo explora o fenômeno e a noção de fake news e examina o impacto dos elementos advindos dos novos ambientes informacionais sobre a epistemologia do testemunho. Após apresentarmos um exame de lições gerais que o quadro conceitual delineado traz à tona, concluímos com notas sobre o impacto dessas lições para a epistemologia do testemunho, em particular.
Anúncios, escravidão e modernidade: as representações contidas no jornal baturiteense A Ordem, Orgão Conservador
Authors: Barbosa Igo Barbosa
Published: November 2022

O presente artigo insere-se na perspectiva da história local e tem como horizonte propor uma breve análise dos anúncios e avisos expostos no jornal baturiteense A Ordem, orgão conservador. Seus exemplares, disponíveis no site da Biblioteca Nacional Digital Brasil, foram produzidos no final da década de 1970 e início da década seguinte, do século XIX. Através da leitura atenta desses segmentos do jornal, comparando e discutindo os elementos escritos e visuais, amparados por uma bibliografia adequada a esse esforço, nos propomos a analisar, de forma geral, a representação do escravizado exposta em suas folhas, bem como acentuar alguns indícios da incipiente modernização do país, expressas localmente. Essas mudanças, baseadas em um ideário mais próximo ao abolicionismo, ia de encontro à manutenção do regime escravista. Primeiramente, esclarecemos o conceito de “representação”, utilizado em grande medida por Chartier, para posteriormente utilizá-lo como uma ferramenta para refletir em torno da imagem do escravizado nessa região, em seguida, discutimos o que entendemos como os indícios da modernização local. Na conclusão, fizemos um breve apanhado do que analisamos nesse trabalho.
Destino Senado Federal
Authors: Centeno Alison Ribeiro
Published: November 2022

Estudando as carreiras políticas e o social background (diplomação escolar e profissão prévia à entrada no meio político) dos que venceram as eleições para a representação federativa no Congresso, objetiva-se: analisar se antigos governadores e prefeitos tinham carreiras mais curtas em relação àqueles que fizeram carreiras somente no Legislativo e se políticos que até então jamais haviam vencido eleições tinham social background destacado em relação aos políticos profissionais. Empreendidos os levantamentos estatísticos, não se observaram disparidades nas carreiras exclusivamente executivas em relação às estritamente legislativas, havendo menor tempo de carreira e de mandatos dessas carreiras em relação as de políticos que passaram por cargos nos dois poderes. Os níveis de experiência política também não estiveram ligados a social background distinto, apresentando o Senado Federal no período como Casa dos políticos profissionais e de alta posição socio-ocupacional.
Morfometría de ovarios, folículos y su relación con la calidad oocitaria en bovinos
Authors: Neira-Rivera Eliana , Velásquez-Penagos José Guillermo , Cardozo-Cerquera Jaime Antonio , Velásquez-Penagos José Henry , Gutiérrez-Parrado Sonia Lucía , Herrera-León Rocío Fenney
Published: November 2022

Introducción. Estudios sobre características estructurales del ovario asociadas con calidad del complejo cúmulos-oocito (COCs) en bovinos, contribuyen con la definición de estrategias para mejorar la eficiencia reproductiva. Objetivo. Determinar el peso y tamaño de los ovarios, calidad de los folículos y COCs en hembras Cebú, para establecer diferencias entre el ovario derecho e izquierdo. Materiales y métodos. Entre marzo y julio del 2017, se obtuvieron 52 ovarios de veintiséis vacas Cebú. Los ovarios y folículos se pesaron y midieron. Los folículos se agruparon en tres categorías: a) <3 mm (TFI), b) 3-6 mm (TFII) y c) >6 mm (TFIII). La calidad de los folículos se determinó mediante la técnica de irrigación-traslucidez (TIT) y la de COCs por las características del citoplasma y células del cúmulo como buena (CI), regular (CII) y mala (CIII), y mediante la prueba azul brillante de cresilo se categorizaron como BCB+ y BCB-. Resultados. La longitud, ancho y peso de los ovarios fueron 2,7 ± 0,6 cm, 1,8 ± 0,5 cm y 7,0 ± 3 g, respectivamente, con diferencias para longitud y peso entre ovario derecho e izquierdo (p<0,01). La mayor cantidad de folículos se obtuvieron en TFI (p<0,05). El 88,56 % de los folículos evaluados fueron de buena calidad. El 52 % y 44,2 % de COCs fueron clasificados como CI y BCB+, respectivamente. Cuando se consideró el tamaño del folículo y la calidad del COCs, se evidenció que en el grupo TFI el 22 % fueron CI, el 34 % CII y el 44 % CIII, y el TFII el 31 % fue CI, el 21 % CII y el 48 % CIII. No se observan diferencias entre ovario izquierdo y derecho. Conclusión. El ovario derecho presentó un mayor tamaño y peso, mayor número de estructuras foliculares y mayor número de CCOs de buena calidad.
Avaliação da qualidade da água do Rio Ijuí utilizando o teste de micronúcleo em peixes
Authors: Da Rosa Neto Emitério , Gehlen Günther , Basso da Silva Luciano
Published: November 2022

As principais fontes de contaminação do Rio Ijuí são o escoamento superficial das lavouras e o esgoto doméstico. O teste de micronúcleo (MN) em peixes é uma ferramenta útil na avaliação da qualidade da água, indicando a presença de substâncias tóxicas. Este estudo teve como objetivo avaliar a qualidade da água do Rio Ijuí utilizando o teste de MN em uma espécie de peixe nativa da família Characidae. Os indivíduos foram coletados no inverno (2012) e no verão (2013) em dois pontos no Rio Ijuí, distantes aproximadamente 170 Km, os quais apresentam a agricultura como principal atividade econômica, mas diferem em densidade demográfica. A frequência de MN não apresentou diferenças entre os locais. No entanto, em ambos os pontos, a frequência de MN no verão (2,15‰ e 2,13‰, nos pontos 1 e 2, respectivamente) foi significativamente maior do que no inverno (0,35‰ no ponto 1 e 0,45‰ no ponto 2). Não houve diferenças significativas para as outras anormalidades nucleares. Os resultados indicam a ocorrência de variação temporal na contaminação mutagênica da água do Rio Ijuí e que pode estar relacionada às atividades agrícolas, já que o verão é o período em que os agrotóxicos são utilizados com maior frequência na região.
Palavras-chave: Biomonitoramento; genotoxicidade; poluição aquática.
estilos de aprendizagem dos professores influenciam no ensino de ciências nos anos iniciais do ensino fundamental?
Authors: De Carvalho Leite Jéssica , Cristina Guimarães Ramos Viviane , De Andrade Ruela Guilherme
Published: November 2022

O ensino de Ciências passou por transformações ao longo do tempo, contudo, algumas questões ainda precisam ser superadas. Ademais, o estilo de ensinar do docente é um reflexo do seu estilo de aprender e se não houver afinidades de estilos entre os professores e alunos, a aprendizagem fica comprometida. Este estudo teve como objetivo compreender os estilos de aprendizagem e as preferências das práticas desenvolvidas em sala de aula no ensino de Ciências pelos professores dos anos iniciais do Ensino Fundamental. Utilizamos uma abordagem quali-quantitativa e amostragem por conveniência. Os instrumentos para a coleta de dados foram: questionário e teste N-ILS (New Index of Learning Styles). Para as análises estatísticas foram utilizados os softwares estatísticos na versão gratuita de testes: Statistica 12 e Statistical Packages for the Social Sciences (SPSS 20). A maioria dos professores apresentaram preferência pelo estilo de aprendizagem sensorial/visual/ativo/sequencial, constatou-se que os docentes enfatizam informações concretas e factuais, organizam o conteúdo de maneira indutiva e consideram que o modo de participação ativa dos alunos facilita o processo educativo.
Palavras-chave: Educação Básica; professores; aprendizado.
sondagem a respeito das pretensões profissionais de graduandos de Engenharia Civil em Passo Fundo
Authors: Bedin Lidiane , Borba Silveira Gabriela , Sá Brito Martins Julia , Vanini Lucas
Published: November 2022

Com os avanços constantes observados no setor construtivo, são perceptíveis as qualificações gradativamente específicas demandadas para o ingresso neste mercado. Nesse viés, observa-se que a graduação em Engenharia Civil deixou de atender parte dos conhecimentos necessários para a plena execução do ofício, sendo fundamental o aperfeiçoamento e a formação continuada quando concluinte. Nesse contexto, se torna relevante o conhecimento das pretensões profissionais dos então graduandos, a fim de se identificar a demanda futura por novos cursos de especialização. Para isso, foi realizado uma sondagem na cidade de Passo Fundo, que se destaca por ser um polo regional de educação e apresentar um mercado consolidado na construção civil, onde foram consultados 104 estudantes de diferentes instituições locais, analisando seu perfil e a manifestação de interesse em buscar uma nova formação. Em parte dos resultados, foram identificadas as áreas mais indicadas pelos graduandos e apresentadas à comunidade acadêmica.
Palavras-chave: Especialização; Engenharia Civil; pretensão profissional.
Prenatal dance activity enhances foetal and postnatal cognitive and motor development
Authors: Bánkyné Perjés Beatrix , Mátrai Gábor , Nagy Bernadett , Erdei Daniella , Makai Alexandra , Prémusz Viktória , Kovács Kálmán András , Bódis József
Published: November 2022

Introduction

No research has examined the impact of any physical-artistic-cognitive activity on foetal neurodevelopment. The aim of the study was to investigate the efficacy of a unique prenatal dance activity in pre- and postnatal cognitive and motor development as a complementary health care practice.

Methods

26 clinically uncomplicated primiparas and multiparas with singleton pregnancies and their later born children were examined in this prospective study at the University of Pécs, Hungary. The activity group participated in supervised, 60-min, twice-weekly, moderate-intensity prenatal dance classes for 19.56 ± 3.97 weeks, whereas the control group did not. We determined the developmental ages of their children with the Bayley Scales of Infant and Toddler Development in both groups at 5 weeks of age and in the activity group at 33 months of age.

Results

Prenatal dance activity did not cause any adverse outcomes. Infants in the activity group had significantly higher mean developmental ages than the control group regarding cognitive skills (P < 0.001), receptive (P < 0.001) and expressive communication (P = 0.007), fine (P < 0.001) and gross motor (P = 0.001). As toddlers their mean developmental ages were significantly higher than their mean calendar age regarding cognitive skills (P = 0.001), receptive (P = 0.001) and expressive communication (P = 0.001), fine (P = 0.002) and gross motor (P = 0.001).

Conclusions

Our results confirm the safe implementation of this prenatal dance activity and the more advanced cognitive and motor development of children in the activity group as infants compared to the control group and as toddlers compared to the norm. These results offer a novel approach to dance in pre- and postnatal clinical practice.
Nem malignus, nem infectiosus lymphoproliferatio: kihívások az autoimmun lymphoproliferativ szindróma diagnosztikájában és kezelésében
Authors: Molnár Emese , Kovács Gábor , Varga Lívia , Tasnády Szabolcs , Bors András , Tankó Lenke , Csabán Dóra , Kapócs Katalin , Nemes-Nagy Zsuzsanna , Andrikovics Hajnalka
Published: November 2022

Összefoglaló. Az autoimmun lymphoproliferativ szindróma egy ritka,
immundeficientiával járó genetikai betegség. Hátterében az extrinszik
apoptotikus útvonal génjeinek örökletes vagy szerzett mutációi és a
következményesen kialakuló, aktivált lymphocyták negatív szelekciójának a
defektusa áll. Az autoimmun lymphoproliferativ szindróma klinikai megjelenésére
jellemző a jóindulatú lymphocytaburjánzás következtében kialakuló
lymphadenopathia és lépmegnagyobbodás. Gyakran társul olyan autoimmun
kórképekkel, mint az autoimmun haemolyticus anaemia vagy az autoimmun
thrombocytopenia. A betegségben jellemző laboratóriumi eltérések a következők:
az αβ+ CD4–/CD8– kettős negatív T-sejtek
szaporulata, a szolúbilis Fas-ligand, az interleukin-10 és interleukin-18,
valamint a B12-vitamin szérumszintjének emelkedése. A kórkép
diagnózisához hozzátartozik az in vitro Fas-mediált apoptózis
funkciójának vizsgálata, valamint a genetikai vizsgálat.
Differenciáldiagnosztikai szempontból fontos elkülöníteni a lymphomáktól,
valamint az autoimmun lymphoproliferativ szindrómaszerű betegségektől. A kezelés
alapja a társuló autoimmun kórképek tüneteinek csökkentése immunszuppresszív
terápiával. Orv Hetil. 2022; 163(4): 123–131.

Summary. The autoimmune lymphoproliferative syndrome is a rare
genetic disorder causing immunodeficiency. In the background of the disease,
germline or somatic mutations of genes participating in the extrinsic apoptotic
pathway and the consequential defect in the negative selection of activated
lymphocytes were discovered. The clinical appearance of autoimmune
lymphoproliferative syndrome consists of non-malignant lymphoproliferation,
lymphadenopathy and splenomegaly, it is frequently accompanied by autoimmune
disorders such as autoimmune haemolytic anaemia or autoimmune thrombocytopenia.
The main diagnostic laboratory findings of this disease are the following: an
elevation in αβ+, CD4–/CD8– double-negative T
cell count, elevated serum levels of soluble Fas-ligand, interleukin-10,
interleukin-18 and vitamin B12. Other useful laboratory tests are the
in vitro Fas-mediated apoptotic functional assay and the
genetic screening for gene mutations. Differential diagnosis should exclude
malignant lymphoproliferation in lymphomas and non-malignant autoimmune
lymphoprolipherative syndrome-like diseases. The main aim of the treatment is
the amelioration of the accompanying autoimmune disease with immunosuppressive
therapy. Orv Hetil. 2022; 163(4): 123–131.
A Kanpó hagyományos orvoslás, ma is támogatott terápiás lehetőség Japánban.
Authors: Blázovics Anna , Csorba Botond
Published: November 2022

Összefoglaló. A japánok hagyományos gyógymódja, a Kanpó a több ezer
éves kínai gyógyító tapasztalaton alapul. A Kanpó filozófiája azonban csak
részben hasonlít a hagyományos kínai orvosláshoz, bár megtartja annak több
fontos alaptételét, de annak egyszerűsített, pozitivista és pragmatikus
változata, amely igazodik a japán kultúrához. A Kanpó a japán
egészségbiztosítási rendszer fontos része a korszerű nyugati gyógymódokkal
együtt. A nyugati orvostudomány viszont kevésbé érdeklődik a Kanpó terápiás
lehetőségei iránt, tekintettel arra, hogy a hagyományos kínai orvoslás és az
Ájurvéda-gyógymódok széles körben elterjedtek a világban az utóbbi néhány
évtizedben. A Kanpó készítményei elérhetők az internet különböző kereskedelmi
honlapjain. Sajnálatos módon a készítmények összetétele általában pontatlanul
van megadva. A gyógynövények fajait nem jelölik, így nemcsak félrevezető, hanem
az összetevők hatása sem ismert. A dolgozat a leggyakrabban használt néhány
hagyományos készítmény összetételét és hatását tárgyalja. Orv Hetil. 2022;
163(110): 386–392.

Summary. Kanpo, the traditional Japanese medicine, is based on
thousands of years of Chinese healing experience. Kanpo’s philosophy, however,
is only partially similar to traditional Chinese medicine. Although it retains
several important basic tenets, it is a simplified, positivist, and pragmatic
version of aligning to Japanese culture. Kanpo is an important part of the
Japanese health insurance system along with modern western therapies. Western
medicine, on the other hand, is less interested in Kanpo’s therapeutic options,
given that traditional Chinese medicine and Ayurvedic therapies have become
widespread in the world over the past few decades. Kanpo’s herbal preparations
are available on various commercial internet websites. Unfortunately, the
composition of the formulas is generally inaccurate. The species of herbs are
not identified, so not only are they misleading, but the effects of the
ingredients are not known either. The article discusses the composition and
effects of some of the most commonly used conventional formulas. Orv Hetil 2022;
163(10): 386–392.
A cauda equina „ancient” típusú schwannomája
Authors: Viczei Alexandra , Patai Tímea , Kiszely Péter , Bodor Anita , Lapis István , Lapis Károly , Szeifert György
Published: November 2022

Összefoglaló. A cauda equina daganatai a leggyakrabban lumbagós
panaszokkal jelentkeznek. Általában késői stádiumban ismerik fel őket, mivel
lassan növekednek, az anatómiai környezet tágas, a megjelenő tünetek nem
specifikusak, valamint az érintett betegek többsége fiatal és egyébként
egészséges. Jelen közleményünkben egy ritka variáns, a cauda equinát érintő
„ancient” típusú schwannoma esetének kórtörténetét és kezelését mutatjuk be.
Műtéti ellátás során a daganat totális eltávolítása történt, ezt követően a
beteg panaszai megszűntek. Ezen daganat klinikai kimutatását preoperatív T1-,
T2-súlyozott MRI tette lehetővé, a pontos diagnózist azonban az eltávolított
daganat patológiai szövettani feldolgozása biztosította. Irodalmi áttekintésünk
alapján a cauda equinában ez a szövettani altípusú schwannoma kifejezetten
ritka: nemzetközi szinten 3 ilyen publikált eset jelent meg, magyar nyelvű
közlést a témában azonban nem találtunk. Orv Hetil. 2022; 163(5): 195–200.

Summary. Tumors of the cauda equina generally present with lower
back pain. They are usually recognized at a late stage as they grow slowly, the
surrounding anatomical environment is spacious, the symptoms that appear are not
specific, and the majority of the affected patients are young and otherwise
healthy. In this paper, we present the diagnosis and treatment of a young male
patient who has undergone the surgical removal of an ancient schwannoma of the
cauda equina. During the operation, the tumor was completely resected, and
following that the patient’s complaints disappeared. The key point to an
accurate diagnosis of this kind of tumor before the operation was the
appropriate radiological study, i.e., T1-, T2-weighted MRI, and
postoperatively the histological processing of the removed neoplasm. Reviewing
the literature, this pathological type of schwannoma appeared to be extremely
rare in the cauda equina: so far, only three cases have been published
internationally, however, we could not find a single paper in the Hungarian
medical literature on this topic. Orv Hetil. 2022; 163(5): 195–200.
Pseudoxanthoma elasticumban szenvedő betegek multidiszciplináris ellátása
Authors: Farkas Klára , Kiss Norbert , Szabó Viktória , Resch Miklós , Vámos Rita , Borbándy Ágnes , Nagy Anikó , Apor Astrid , Arányi Tamás , Szeri Flóra , Wikonkál Norbert , Nagy Zoltán , Merkely Béla , Medvecz Márta
Published: November 2022

Összefoglaló. A pseudoxanthoma elasticum (PXE, OMIM # 264800) egy
autoszomális recesszív módon öröklődő multiszisztémás érintettséggel járó
kórkép, melynek háttérében az ABCC6 gén mutációi állnak. A
tünetek kialakulásának oka az ektópiás mineralizáció. Kalcium-só kristályok
rakódnak le elsősorban a bőrben, a szem Bruch-membránjában és az erek
endotheliumában, így a bőrelváltozások mellett a látás csökkenése és
cardiovascularis eltérések is jelentkezhetnek. A klinikai tünetek változó
súlyosságúak lehetnek, heterogén megjelenésűek. A betegek fenotípusának
azonosítása, valamint gondozása multidiszciplináris feladat, bőrgyógyász,
szemész, kardiológus és klinikai genetikus együttműködésén alapul. Célunk, hogy
bemutassuk a betegségben előforduló tüneteket, melyek ismerete megkönnyíti a
kórkép felismerését, illetve hogy felhívjuk a figyelmet a korai diagnózis
fontosságára és ismertessük a korszerű diagnosztikai módszereket. A súlyos
szisztémás tünetek kialakulása miatt rendkívüli jelentőséggel bír a társszakmák
együttműködése, hogy a korai diagnózis által időben megfelelő gondozásban és
terápiában részesülhessenek a betegek. Orv Hetil. 2022; 163(18): 702–711.

Summary. Pseudoxanthoma elasticum (PXE, OMIM # 264800) is an
autosomal recessive, multisystemic disorder, associated with mutations of the
ABCC6 gene. Ectopic mineralization is in the background of
the clinical manifestations of the disease. Calcium-salt crystals are deposited
primarily in the skin, in the Bruch membrane of the eyes, and in the vascular
endothelium. Thus, in addition to the skin lesions, visual impairment and
cardiovascular involvement also occur. Clinical symptoms show varying severity
and display heterogeneous appearance. The identification of the phenotype and
care of the patients require a multidisciplinary perspective based on the
collaboration of a dermatologist, ophthalmologist, cardiologist, and clinical
geneticist. The aim of our work is to describe the development of symptoms of
the disease, in order to facilitate the diagnosis. In addition, we aim to draw
attention to the importance of early diagnosis of pseudoxanthoma elasticum, and
to present modern diagnostic methods. Considering the development of severe
systemic complications, the early diagnosis with the collaboration between
related specialists is crucial to provide optimal clinical care and management
of the patients. Orv Hetil. 2022; 163(18): 702–711.
Módosított Kleinsasser-laringoszkóp bemutatása két eset kapcsán
Authors: Rovó László , Pfiszterer Péter , Madani Shahram , Bach Ádám
Published: November 2022

Összefoglaló. Az algaratot és a gégét érintő, minimálisan invazív
transoralis műtéti eljárások elvégzésekor elsődleges ezen relatíve szűk
anatómiai régiók megfelelő feltárása. A hagyományos operációs endoszkópok
lehetővé teszik ugyan a műtéti terület kellő vizualizációját, kialakításukból
adódóan azonban nem optimálisak a különböző mikrosebészeti eszközök
koordinációja és szimultán használata szempontjából. A mikroszkóp és a feltáró
eszköz közötti relatíve nagy távolság pedig negatívan hat a célterület
megvilágíthatóságára és a lézernyaláb fizikai tulajdonságaira is. A szerzők egy,
az algaratot, valamint a gégét érintő elváltozások lézer-mikrosebészetében
használt feltáróeszközt módosítottak: az endoszkóp oldalain kialakított nyílások
lehetővé teszik a mikrosebészeti eszközök oldalsó bevezetését, emellett a
mikroszkóp és a célterület közötti távolság jelentős csökkentését. A glotticus
területet és a nyelvgyököt érintő műtét kapcsán bemutatott módosított operációs
endoszkóp lehetővé teszi a műtéti terület megfelelő feltárását, a lézer
optimális használatát és több mikrosebészeti eszköz egyidejű, szabad mozgatását.
Orv Hetil. 2022; 163(17): 688–692.

Summary. In cases of transoral laryngeal and hypopharyngeal
surgeries, the exploration of these relatively narrow anatomical regions is
paramount. The conventional operational endoscopes allow the visualization of
the surgical field, but – due to their structure – are not optimal regarding the
coordination and simultaneous moving of microsurgical instruments. Furthermore,
the relatively great distance between the surgical microscope and the endoscope
has a negative impact on the illumination of the surgical area and the physical
characteristics of the laser beam. The authors introduce a modified laryngoscope
used in the field of laryngeal and hypopharyngeal surgery. The openings in the
sides of the endoscope allow the lateral insertion of microsurgical devices,
while the distance between the microscope and the target area can be
significantly reduced. The endoscope is presented in addition to a tongue base
and a glottic surgery. The introduced operational endoscope allows optimal
exploration of the area of interest, the free and simultaneous moving of the
microsurgical instruments, and the optimal usage of the laser beam. Orv Hetil.
2022; 163(17): 688–692.
Morel-Lavallée-laesio: egy ritka, kiterjedt, zárt lágyrész-sérülés.
Authors: Burkus Máté , Pfäfflin Hartmut , Zdichavsky Marty , Bruch Andreas
Published: November 2022

Összefoglaló.A Morel-Lavallée-laesio egy többségében kiterjedt, décollement-nek megfelelő, zárt lágyrész-károsodás, mely a leggyakrabban a hát, a medence, illetve a combok környékén fordul elő; eredete elsősorban közlekedési balesetekhez, sportsérülésekhez kötött. A sérülés gyakran társulhat a medencekörnyéki csontok érintettségével, esetleg többszörös traumával, azonban önálló megjelenése is előfordul. Megfelelő kezelésében nagy jelentőségű a károsodás időben történő felismerése és célzott terápiája, melynek során elsősorban a sebészeti kezelés preferált. A nem megfelelően kezelt eseteknél a panaszok lassan progrediálhatnak, az elváltozás krónikussá is válhat. Kiemelendő, hogy az érintettek nem elhanyagolható része nem feltétlenül centrumintézménybe jelentkezik, hanem önállóan előforduló, krónikus vagy panaszos esetekben gyakran kisebb kórházakban vagy éppenséggel szakrendeléseken jelenhetnek meg. A Morel-Lavallée-laesióval kapcsolatos magyar nyelvű irodalom szegényes. A jelen közleménnyel a szerzők célja, hogy ismertessék az általuk nem centrumintézményben kezelt, deréktáji érintettséggel rendelkező két eset példájához társítva a sérüléssel kapcsolatos legfontosabb tudnivalókat. Orv Hetil. 2022; 163(16): 645–650.

Summary.Morel-Lavallée lesion is an extensive, decollement-like closed degloving soft-tissue injury. It occurs most commonly in the thigh, pelvis or lumbar region, primarily due to traffic accidents or sports injuries. The injury is often associated with pelvic or femoral fractures and polytrauma but it may occur separately. Early diagnosis and specific treatment are critically important to achieve adequate therapy in which the operative approach is preferred. If not treated properly, complaints may progress and the condition can become chronic. It should be highlighted that a considerable number of patients suffering from this condition may not present in central institutions but in minor hospitals or outpatient units with separately occurring, chronic or painful injury. Morel-Lavallée lesion is rarely mentioned in the Hungarian literature. The authors aim to present the most important knowledge about the injury in accordance with the case presentation of two patients with lumbar complaints they treated in a non-central institution. Orv Hetil. 2022; 163(16): 645–650.
Sinusbradycardia mint lehetséges favipiravir-mellékhatás
Authors: Szigeti József
Published: November 2022

Összefoglaló. A koronavírus–19-pandémia hatalmas kihívás az
egészségügyi ellátórendszerek számára. A hatékony kezelés iránti igény
felerősítette a terápiás megoldásokra való törekvéseket. Ennek egyik eleme a
favipiravir hatóanyag széles körű ambuláns és intézeti alkalmazása. A gyógyszer
biztonsági információi korlátozottan említik a lehetséges cardialis
mellékhatásokat: mindösszesen az igen ritka mellékhatások között lelhető fel a
„szívritmuszavar” megjegyzés. A közlemény a favipiravirkezeléshez köthető
átmeneti sinusbradycardia esetét ismerteti. Orv Hetil. 2022; 163(7):
267–270.

Summary. The coronavirus pandemic is an enormously high challenge
for medical health services worldwide. The demand for effective treatment
amplified the pursuits for therapeutic solutions. One element of the possible
treatment is the use of favipiravir in outpatient departments and hospitals.
Safety information of favipiravir is limited with the risk of potential cardiac
side effects: only the two words of „rhytm disturbances” can be found among the
very rare side effects. This article describes the case of favipiravir-induced
transient sinus bradycardia. Orv Hetil. 2022; 163(7): 267–270.
Perinatalis stroke: vizsgálati irányelv
Authors: Vojcek Eszter , Seri István
Published: November 2022

A perinatalis stroke egy heterogén neurológiai szindróma, mely agyi érsérülés
következtében alakul ki, és hosszú távon általában krónikus neurológiai
kimenetellel jár. Az akut stroke-ok közé a perinatalis artériás ischaemiás
stroke, a sinusthrombosis és a perinatalis vérzéses stroke tartozik. A később,
általában 4–8 hónapos kor között motoros aszimmetriát okozó kórképeket
feltételezetten perinatalis eredetű stroke-nak nevezzük. A mágneses rezonanciás
(MR) képalkotás széles körű használatával az elmúlt években egyre gyakrabban
diagnosztizálnak bizonyítottan perinatalis stroke-ot. Az újabb adatok szerint a
perinatalis stroke incidenciája 1 körül van 1100 élveszületésből (1/1100). Bár a
stroke-os újszülöttek 40%-a később tünetmentesen fejlődik, a többiek hosszú távú
neurológiai kimenetele kóros, és a károsodás spektrumához cerebralparesis,
epilepszia, kognitív károsodás, magatartászavar, beszédzavar és/vagy valamilyen
érzékszervi károsodás tartozik. Az utóbbi időben több tanulmány vizsgálta a
rizikótényezők, az MR-képek és a kimenetel összefüggését. A jelen összefoglaló
közleményben a perinatalis stroke epidemiológiáját, tüneteit, kivizsgálását,
kezelését és kimenetelét, valamint a képalkotás formáit részletezzük. Az akut
perinatalis stroke vizsgálatának menetéről és terápiájáról irányelvet
készítettünk. Orv Hetil. 2022; 163(24): 952–960.
Ciszteamintartalmú szemcsepp alkalmazása cystinosisban
Authors: Csorba Anita , Maka Erika , Szabó Attila , Kelen Kata , Reusz György , Nagy Zoltán Zsolt
Published: November 2022

A cystinosis ritka, aminosav-anyagcserét érintő, lizoszomális tárolási
megbetegedés, melyben jellegzetes eltérés a cisztin felszaporodása és
kikristályosodása a különböző szervekben, szövetekben, elsősorban a szemben és a
vesében. Szemészeti vonatkozásban kiemelkedő jelentőségű a cisztinnek a
corneában való lerakódása, ami nagyfokú fényérzékenység kialakulásához vezet. A
kifejezett fényérzékenység jelentősen rontja az érintett páciensek
életminőségét, így a kristályok mennyiségének csökkentését célzó hatékony
szemészeti kezelés kiemelt szereppel bír. Esettanulmányunk kapcsán a
szakirodalom áttekintésével mutatjuk be a cystinosis jellegzetes szemészeti
klinikai megjelenését és kezelési lehetőségeit. A lokális kezelésben korábban
széles körben alkalmazták a kristályok feloldását elősegítő ciszteamin egyszerű
vizes oldatát, e készítmény terápiás hatékonysága azonban vitatott. Újabban a
ciszteamin új, viszkózus oldatának alkalmazására nyílt lehetőség. A 29 éves
férfi betegünknél a cornealis cisztinkristályok kezelésére viszkózus formátumú,
ciszteamintartalmú készítményt vezettünk be, és ezt alkalmaztuk 1 éven át.
Páciensünknél az új lokális szemcsepp használata mellett a kezelés megkezdését
követő egy évben a fényérzékenység jelentős, fokozatos csökkenését figyeltük
meg. Elülső szegmens optikaikoherencia-tomográfiás és in vivo
konfokális mikroszkópos vizsgálatainkkal kimutatható volt a cornealis kristályok
mennyiségének folyamatos csökkenése már az 1. hónaptól kezdve. Jelen
közleményünk célja, hogy felhívja a figyelmet a cystinosis szemészeti tüneteire,
illetve a Magyarországon elsőként alkalmazott, viszkózus formátumú
ciszteaminkezelés hatékonyságára. Orv Hetil. 2022; 163(21): 846–852.
Takhrij Hadith the Importance of Silaturahmi in the Islamic World
Authors: Ghoni Muhamad Ilman Maulana Nata Abdul , Busro Busro
Published: November 2022

This study aims to discuss the hadith about friendship. This study uses a qualitative approach by applying the descriptive-analytical method. The formal object of this research is takhrij hadith within the scope of hadith science, while the material object is the hadith about friendship in the history of Bukhari no. 5527. The results and discussion of this study indicate that the quality of the hadith regarding friendship is assessed as maqbul ma'mul bih with hasan li ghairihi qualifications. This study concludes that the hadith narrated by Bukhari no. 5527 is relevant to be used as a motivation for increasing friendship in the Muslim community.
Takhrij Hadith Types of Major Sins in Islam
Authors: Indriyani Diva Nur , Wibisono M. Yusuf
Published: November 2022

This study aims to discuss the hadith about major sins. This study uses a qualitative approach by applying a descriptive-analytical method. The formal object of this research is the takhrij hadith within the scope of hadith science, while the material object is the hadith about major sins in the history of Bukhari no. 6182. The results of the research and discussion show that the status of hadith is of authentic quality which is not only maqbul but maqbul ma'mul bih as the basis for practicing Islam in avoiding major sins. This study concludes that the major sins in Islam include associating partners with Allah, disobeying one's parents, killing, and perjury. In addition, the act of adultery is a major sin which is strictly prohibited in Islam.
Physical and chemical properties of rice varieties grown in Mekong delta
Authors: Lai Dat Quoc , Ngo Thanh An , Nguyen Quang Long , Nguyen Hoang Dung , Pham Duy Tien
Published: November 2022

125 rice samples of 10 rice varieties (Daithom8, IR50404, Jasmine85, DS1, OM4900, OM5451, OM6976, OM7347, ML202, Glutinous rice) collected from 10 provinces in the Mekong Delta were not different in grain length ranging from medium to long and were mainly tapered in shape. Except for DS1, because of the Japonica variety, it is round in shape. Their chemical ingredients slightly differed between varieties, but there was a clear difference in amylose content, according to which these rice samples were divided into 4 groups: samples with very low amylose content ranging from 3 to 9 %, accounting for 3 % of the total samples and belonging to the Glutinous rice variety; samples with medium amylose content (20 - 25 %), accounting for 29 % of the total samples and mainly belonging to varieties Jasmine85 and OM5451; samples with high amylose content (≥ 25 %), accounting for 20 % of the total samples and belonging to varieties IR50404, ML202, and OM6976; and samples with low amylose content (9 - 20 %), accounting for 48 % of the total samples and belonging to the remaining varieties. Based on physical and chemical properties, the rice varieties of 125 survey samples were classified into 3 groups with specific characteristics. In group 1, samples were characterized by particle size, particle shape, moisture, lipid and ash content; in group 2, samples were characterized by properties such as starch and amylose content; group 3 was characterized by width, protein and amylopectin. In addition, rice samples were divided into 3 groups based on growing location and physicochemical properties.