bluuebunny/crossref_metadata_2025 huggingface dataset:
INTERNET ADVERTISING AND CONSUMPTIVE LIFESTYLE OF THE STUDENTS
Authors: Anwar Rully Khairul , Lusiana Elnovani , Rahman Mohammad Taufiq
Published: July 2019

This paper discusses about how mass media as part of society has been widely used in addition being a media of information and entertainment, as well as a media of persuasion. In this case the researcher looked at the exposure of internet advertising that was part of the effort to promote goods and services from producers to the public as consumers. Researchers were intrigued to find out more about whether advertisements on internet mass media that contain more commercial advertisements and become part of economic activities can affect the behavior of students as teenagers that can lead to consumptive nature that is used to be a lifestyle. The student's consumptive lifestyle as a result of being hit by advertisements on the internet mass media is seen from the number of goods ownership such as female students who have a number of beauty equipment with different brands and gadget more than one. And men are more visible on gadgets alone, they are more likely to have more than one gadget, even though one of them can still be used.
KETIMPANGAN SEBAGAI PENYEBAB KONFLIK: KAJIAN ATAS TEORI SOSIAL KONTEMPORER
Authors: Zuldin Muhamad
Published: July 2019

This article reviews the relationship between inequality and social conflict in society. This literature review finds that there are at least four schools of thought in contemporary conflict theory that examine the relationship of inequality to conflict. The first is the flow of positive thought which includes the theory of structural conflict. Second is the flow of humanism thinking which consists of symbolic interactions and social construction theory. The third is the school of thought which consists of the thoughts of Jurgen Habermas and Pierre Bourdieu. And the last is a multi-disciplinary school built by Johan Galtung and Anthony Giddens. The four schools of thought develop classical conflict theory, especially Marx's thought that argues that economics is the only factor of conflict in society.
Pair of generalized derivations acting on multilinear polynomials in prime rings
Authors: DHARA Basudeb , KAR Sukhendu , DAS Priyadwip
Published: July 2019

Let $R$ be a noncommutative prime ring of characteristic different from $2$ with Utumi quotient ring $U$ and extended centroid $C$ and $f(r_1,\ldots,r_n)$ be a multilinear polynomial over $C$, which is not central valued on $R$. Suppose that $F$ and $G$ are two nonzero generalized derivations of $R$ such that $G\neq Id$ (identity map) and $$F(f(r)^2)=F(f(r))G(f(r))+G(f(r))F(f(r))$$ for all $r=(r_1,\ldots,r_n)\in R^n$. Then one of the following holds:(1) there exist $\lambda \in C$ and $\mu \in C$ such that $F(x)=\lambda x$ and $G(x)=\mu x$ for all $x\in R$ with $2\mu=1$;(2) there exist $\lambda \in C$ and $p,q\in U$ such that $F(x)=\lambda x$ and $G(x)=px+xq$ for all $x\in R$ with $p+q\in C$, $2(p+q)=1$ and $f(x_1,\ldots,x_n)^2$ is central valued on $R$;(3) there exist $\lambda \in C$ and $a\in U$ such that $F(x)=[a,x]$ and $G(x)=\lambda x$ for all $x\in R$ with $f(x_1,\ldots,x_n)^2$ is central valued on $R$;(4) there exist $\lambda \in C$ and $a,b\in U$ such that $F(x)=ax+xb$ and $G(x)=\lambda x$ for all $x\in R$ with $a+b\in C$, $2\lambda =1$ and $f(x_1,\ldots,x_n)^2$ is central valued on $R$;(5) there exist $a, p\in U$ such that $F(x)=xa$ and $G(x)=px$ for all $x\in R$, with $(p-1)a=-ap\in C$ and $f(x_1,\ldots,x_n)^2$ is central valued on $R$;(6) there exist $a, q\in U$ such that $F(x)=ax$ and $G(x)=xq$ for all $x\in R$ with $a(q-1)=-qa\in C$ and $f(x_1,\ldots,x_n)^2$ is central valued on $R$.
2018 ESC Guidelines for themanagement of cardiovascular diseases during pregnancy (text is available in electronic version doi:10.15829/1560-4071-2019-6-151-228)
Authors: Editorial Article
Published: July 2019

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Differentiated approach in diagnostics, diagnosis formulation, case management and statistical accounting of type 2 myocardial infarction (Position Paper)
Authors: Averkov O. V. , Barbarash O. L. , Boytsov S. A. , Vasilieva E. Yu. , Drapkina O. M. , Galyavich A. S. , Gilyarov M. Yu. , Zayratiants O. V. , Kakturskiy L. V. , Karpov Yu. A. , Mishnev O. D. , Nikulina N. N. , Orekhov O. O. , Samorodskaya I. V. , Soboleva G. N. , Cherkasov S. N. , Shakhnovich R. M. , Shilova A. S. , Shlyakhto E. V. , Shpektor A. V. , Yavelov I. S. , Yakushin S. S.
Published: July 2019

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Automated construction: boosting on-site productivity using a platform-based approach
Authors: Masters Kevin , Johnston Jaimie
Published: July 2019

Since 2018, the UK government has been supporting a new approach to construction, called a platform approach to design for manufacture and assembly. It bridges the gap between manufacturing and construction, offering lower costs through economies of scale, reduced waste and higher productivity but retaining sufficient flexibility for architectural freedom. The approach was first developed and prototyped in the UK prison estate transformation programme, although for commercial expedience it was not implemented. This paper discusses the lessons learned from the prototypes and the opportunities for the two platforms to be applied on future programmes for prisons as well as homes, hospitals, schools and many other building types.
A decision support tool for assessing risks to above-ground river pipeline crossings
Authors: Maniatis Georgios , Williams Richard D. , Hoey Trevor B. , Hicks John , Carroll William
Published: July 2019

Infrastructure assets require suitable management and assessment protocols due to age-related deterioration, extreme weather events and climate change impacts. Above-ground river crossings are weak links in pipe networks since bank erosion and scour can undermine the integrity of built structures. A simple protocol was developed to assess river bank stability in the vicinity of river pipeline crossings. The erosion risk index (ERI) follows established bank erosion estimation techniques, adapted for users who are not trained geomorphologists. Calculation of the ERI is based on analysis of photographs acquired during an optimised inspection protocol using a custom app on a ruggedised tablet computer. The ERI was tested across Scotland and proved to be adequate for a first-order geomorphological assessment and to provide a classification of crossings according to susceptibility to river bank erosion. The ERI is transferable, with appropriate testing, to other infrastructure river crossing networks in the UK and beyond. The methodology used to develop and test the ERI is applicable to the development of other protocols to manage and assess infrastructure assets.
Tokat ve Niksar'da Bazı Selçuklu Yapılarındaki Çini Süslemeler Üzerine Bir Değerlendirme
Authors: DENKNALBANT ÇOBANOĞLU Ayşe
Published: July 2019

Tokat ve Niksar, XII.-XIII. yüzyıllarda Danişmendliler ile Selçuklular döneminde önemli merkezler olarak karşımıza çıkmaktadır. Bölgede bu süreçte inşa edilen yapılar gerek planları gerekse de süsleme özellikleri bakımından Türk mimarisi içinde önemli örneklerdir. Söz konusu yapılar, şüphesiz araştırmalara konu olmuş ve çeşitli vesilelerle çalışılmıştır. 2012 senesinden itibaren özellikle Tokat merkez ve Niksar’da yaptığımız çalışmalar, yapıların hem mimari hem de süsleme özellikleriyle dikkatimizi çeken bazı unsurlarını ortaya çıkarmış bulunmaktadır. Bu makalede, Tokat ve Niksar’daki alan çalışması sonucunda elde ettiğimiz veriler ışığında, Selçuklu dönemi yapılarında uygulanmış olan çini süsleme programlarıyla ilgili bulgular ve tespitler ele alınmıştır. Tokat merkezde bulunan Şeyh Meknûn Zaviyesi, zaman içinde harap duruma düştükten sonra restorasyon çalışmaları geçirmiştir. Eski kaynaklar ve resimlerden öğrendiğimiz üzere, yapının kubbeli sofa, eyvan ve türbe bölümleri zengin bir çini dekorasyonuna sahipti. Günümüze bunlardan yalnızca türbe bölümündeki çinilerden bir kısmı ulaşmıştır. Tokat Yağıbasan Medresesi’nde 2000’li yılların başında yapılan bir restorasyon çalışmasında ise güney eyvan duvarında in-situ durumunda altıgen formlu firuze renkli çiniler tespit edilmiştir. Yine Selçuklu döneminden Murad Sevdekâr Türbesi’nde çini izleri günümüze kadar ulaşmış, Sefer Paşa Türbesi’nde ise çini bulunduğuna dair bazı izler daha önceki araştırmacılar tarafından kayıt edilmiştir. Niksar’daki alan çalışmamız sırasında ise, Yağıbasan Medresesi’nin yanında, bahçe olarak düzenlenen alanda mozaik çini tekniğinde yapılmış, bir kitabeye ait olduğunu tahmin ettiğimiz bir parça dikkatimizi çekmiştir. Niksar’da bu parçayla ilgili olabilecek yapılar incelendiğinde, çini süslemelere sahip olduğu kaynaklardan bilinen Sunguriye Türbesi’ne ulaşılmaktadır. Türbenin günümüze yalnızca gömü odası ulaşmış vaziyette olup, harap durumdaki üst katı 1940’lı yıllarda yıktırılmıştır. Bu çalışmada, Sunguriye Türbesi ile ilgili yazılı ve görsel kaynaklarında yardımıyla, buradaki çini süsleme programı ve tespit edilen çini mozaik parça arasında bir bağlantı olup olamayacağı belirlenmeye çalışılacaktır.Tokat’ta XII-XIV. yüzyıllar içinde inşa edilmiş yapılardaki verilerin ışığında, çini süslemelerin bütüncül olarak değerlendirildiği bu çalışmada herkes tarafından bilinen Gök Medrese’den başka, aynı dönemde inşa edilmiş yapılarda da, bir kısmı günümüze ulaşamamış olsa da zengin bir çini kullanımının söz konusu olduğu ortaya konmaktadır.
When do low-frequency measures really measure transaction costs?
Authors: Jahan-Parvar Mohammad R. , Zikes Filip
Published: July 2019

We compare popular measures of transaction costs based on daily data with their high-frequency data-based counterparts. We find that for U.S. equities and major foreign exchange rates, (i) the measures based on daily data are highly upward biased and imprecise; (ii) the bias is a function of volatility; and (iii) it is primarily volatility that drives the dynamics of these liquidity proxies both in the cross section as well as over time. We corroborate our results in carefully designed simulations and show that such distortions arise when the true transaction costs are small relative to volatility. Many financial assets exhibit this property, not only in the last two decades, but also in the previous century. We document that using low-frequency measures as liquidity proxies in standard asset pricing tests may produce sizable biases and spurious inferences about the pricing of aggregate volatility or liquidity risk.
An Empirical Research on Hotel Employees’ Acceptance Intention of Blockchain-based Hotel Reservation System
Authors:   The Tourism Sciences Society Of Korea, Kim Su-Jeong , Yoon Ji-Hwan
Published: July 2019

This research aims to figure out how hotel Employees would react in accepting blockchain technology, a new innovative technology. Despite social interests and various advantages of blockchain, it still remains a new technology in the field of tourism which has not been spread widely. Thus, based on Technology Acceptance Model (TAM), we attempted to check the extent of acceptance. The characteristics of blockchain were categorized as security, reliability and economy according to the hotel reservation field and the research attempted to figure out the influences that these characteristics have on perceived ease, perceived usefulness, perceived value and acceptance intention. A total of 275 hotel Employees dealing with hotel reservation system were surveyed to verify this. Research analysis showed that among blockchain characteristic variables, the factor of economy was found to affect perceived ease but did not have an influence on perceived usefulness and perceived value. Security showed a influence on perceived usefulness and perceived value but did not have an influence on perceived ease. In addition, reliability showed a positive influence on perceived value, perceived usefulness, perceived ease and the rest of the hypothesis were all proven valid.
The Structural Relationships among Perception of Preservation and Utilization, Place Attachment, and Attitude toward Cultural Heritage
Authors:   The Tourism Sciences Society Of Korea, Kim Seong-Jo , Kim Jae-Hak
Published: July 2019

This study examined the structural relationships among the perception of preservation and utilization, place attachment, attitude, and the mediating effect of cognitive attitude in cultural heritage. A total of 331 respondents who visited the cultural heritage sites during Cultural Heritage Yahaeng completed a survey in Cheongju, South Korea. Structural Equation Modelling was then used to examine the relationships and effects among variables. The results showed that both preservation and utilization perception of cultural heritage positively influenced place attachment and place attachment positively influenced cognitive attitude. However, behavioral attitude was influenced by only place dependence. On the other hand, cognitive attitude was found to fully mediate the relationship between place identity and behavioral attitude, while partially mediate the relationship between place dependence and behavioral attitude. These findings indicate that both cultural heritage preservation and utilization perception are significant predictors of place attachment and place attachment also could be an antecedent of attitude formation. Furthermore, the results imply that those of tested variables are important factors in considering comprehensive cultural heritage policy and management. Based on these results, academic and practical implications and recommendations for the sustainable cultural heritage are provided.
Test v1
Authors: Shirazi Alex
Published: July 2019

This is a test protocol. It will remain private.
Transposase injection mix protocol v1
Authors: Matthews Ben
Published: July 2019

This protocol details the steps necessary to generate injection mixes (comprised of plasmid DNA for integration and transposase mRNA) for transposon-mediated integration into Aedes aegypti and other insects. It has been empirically tested in Ae. aegypti embryos with piggyBac transposase. In our hands, using mRNA as a source of transposase instead of a helper plasmid increases transformation rates substantially.
Instagramdan Hikaye Reklamlar: Tüketici Tutum ve Davranış Eğilimleri Üzerine Bir Araştırma
Authors: BOZKURT Yasemin
Published: July 2019

Ülkemizde en çok tercih edilen sosyal medya platformlarının platformlarının başında, Instagram gelmektedir. Instagram platformu, özellikle akıllı telefonlar için tasarlanmış, genellikle görsel içerikler paylaşmak üzerine geliştirilmiş, ücretsiz olarak indirilip kullanabilme özelliği bulunan çevrimiçi ortamlardır. Bu ortamın, son yıllarda hikayeler bölümüyle ön plana çıktığı görülmektedir. Instagram Mart 2017’de hikayeler bölümüne reklam almaya başlamıştır. Instagram hikaye reklamları, bir markaya ait Instagram hesabı aracılığıyla aktarılmak istenen mesajların fotoğraf ya da video şeklinde paylaşıldığı ve kullanıcıların takip ettiği hesapların öyküleri arasında açılan uygulamalardır. Instagram hikayelerini kullanan kitlelerin hızla büyümesi nedeniyle bu kitlelere ulaşmaya çalışan reklamcılar ve reklamverenleri daha fazla hikaye reklamları kullanmaya yöneltmektedir. Dolayısıyla Instagram kullanıcılarının hikaye reklamlar hakkında nasıl bir tutum ve davranış eğilimine sahip olduğu önem kazanmaktadır. Çünkü bu kullanıcıların hikaye reklamları kabul ya da reddetmelerinin, yaklaşım biçimlerinin; bu hikayeleri takip etmelerini ve hikayelerin amacına ulaşmasını doğrudan etkilediği düşünülmektedir. Bu doğrultuda literatürdeki konuyla ilgili bilgi boşluğunun da etkisiyle bu çalışmanın amacı, tüketicilerin Instagram hikayelerine yönelik tutum ve davranış eğilimlerini belirlemektir. Amaca dayalı örneklem yöntemi kullanılarak Instagramın hikayeler bölümünü takip eden katılımcılara yüzyüze ve çevrim içi ortamda anket uygulanmıştır. 423 anketin analize dahil edildiği araştırma sonucuna göre, katılımcıların hikaye reklamlara yönelik genel olarak olumsuz tutuma sahip oldukları, beklenen davranış tepkilerini göstermedikleri ve bu davranışların da hikaye reklama yönelik tutumlardan doğrudan etkilendiği belirlenmiştir.
Türkiye’deki Kitle Fonlama Web Sitelerinin Kullanılabilirlik ve Görsel Estetik Kavramları Bağlamında Görsel İletişim Tasarımı Değerlendirmesi
Authors: AYTEKİN Behiç
Published: July 2019

Kitle fonlama ekosistemini; girişimciler, melek yatırımcılar, sponsorlar, kitle fonlama web siteleri, teknoparklar, hobiciler ve çevrimiçi teknoloji takipçileri arasında şekillenen bir üretim-iletişim-tüketim ağı yapısı olarak tanımlamak mümkündür. Çok sayıda paydaşın aynı etkileşim kurgusu dahilinde etkilenmesi söz konusu olduğu için, ekosistemin doğal olarak demokratik bir iletişim ve etkileşim ortamı yarattığı düşünülmektedir. Ekosistem sayesinde; girişimciler herhangi bir etkin sermayenin yönlendirmesine maruz kalmadan, projelerini üretim ve dağıtım düzeyine, kurumsal bir ölçeğe sahip bir marka değerine ulaştırabilmeleri mümkün olmaktadır. Böylelikle oldukça demokratik ve açık bir üretim döngüsü ortamı yaratılmaktadır. Bu yapısal özellikler bağlamında, kitle fonlama projelerinin bütçesel anlamda kaynaklanması için ilgili paydaşlara sunulduğu ve bu paydaşlar ile etkileşimli bir iletişim ortamının yaratıldığı web siteleri de özel bir önem kazanmaktadır. Bu nedenle, Türkiye’de varlık gösteren kitle fonlama web siteleri (buluşum, crowdfon, fongogo ve arıkovanı) sistem kullanılabilirlik ölçeğinden (System Usability Scale) adapte edilen web kullanılabilirlik ölçeği (Web Usability Scale) ile kullanıcı etkileşimi ve kullanılabilirlik düzeyinde ölçümlenmekte ve çalışma özelinde yaratılan tasarım değerlendirme şablonu (TDŞ) ile görsel iletişim tasarımı özellikleri üzerinden değerlendirilmektedir (n=10). Böylelikle kitle fonlama projelerinin ilgili paydaşlara sunulabildiği tek kanal olan bu iletişim köprülerinin, üzerlerine düşen etkileşim sorumluluğunu ne ölçüde yerine getirebildikleri, kullanılabilirlik fonksiyonu ile görsel iletişim tasarımı standartları bağlamı ilk kez bir araya getirilerek tartışmaya sunulmaktadır.
Kamu Diplomasisi Aracı Olarak Medya: TRT World Örneği
Authors: BARİTCİ Fatih , AYDENİZ Hediyetullah
Published: July 2019

Soğuk Savaş dönemi kavramı olan kamu diplomasisi, uluslararası ilişkilerin bir faaliyet
alanı ve iletişim süreç yönetimi olarak tanımlanmaktadır. Bir hükümetin ulusal amaçlarının
ve güncel politikalarının olduğu kadar ulusunun fikir ve ideallerinin, kuruluşlarının ve
kültürünün muhatap ülkelerin halkınca anlaşılması amacıyla bilgilendirilmesi ve o halkların
ulusal menfaat çerçevesinde dış politikalara dâhil edilmesi amacıyla gerçekleştirilen iletişim
sürecidir. Medya bu iletişim sürecinin yönetilmesindeki en önemli araçlardan birisidir. Hızlı,
kolay ve etkin bir şekilde muhataplara ulaşabilme kabiliyeti bakımından medya, kamu
diplomasisi aracı olarak kullanılmaktadır. Ayrıca internetin yaygınlaşması ve sektörel işleyiş
bakımından medyanın bundan yararlanmasıyla medya türleri arasında dâhil edilen “yeni
medya”, basılı, işitsel ve görsel medyayı kapsayan geleneksel medyanın işleyişi açısından da
kamu diplomasisi ile ilgili çalışma ve tartışmalar noktasında önemli bir role ve etkiye sahip
olmuştur. Bu çalışmada 2015 yılında yayına başlayan ve TRT’nin İngilizce olarak dünyaya
yayın yapan ilk kanalı olan TRT World, yeni medya da dikkate alınarak, bir yöntem olarak da
kabul edilen tarihsel sosyolojik yaklaşımdan yararlanılarak Türkiye’nin kamu diplomasisi
faaliyetleri kapsamında ele alınmaktadır. Kamu Diplomasisi Koordinatörlüğü’nün
çalışmalarından hareketle tespit edilmeye çalışılan Türkiye’nin kamu diplomasisi stratejisi
ve bunun bir parçası olarak değerlendirilen TRT World, nitel yöntemlerden birisi olan
vaka incelemesi/durum çalışması (case study) çerçevesinde ele alınmıştır. Bu çerçevede
çoklu veri kaynaklarından ve veri toplama tekniklerinden yararlanılarak (istatistikler, yarı
yapılandırılmış görüşme, dökümün incelemeleri, röportajlar, vb.) TRT World’un “kuruluş
süreci, amaç ve hedefleri, bütçesi, organizasyonel yapısı, personel politikası, hedef kitlesi,
konumlandırılması, haber stratejisi, TV programları, resmi web sayfası ve sosyal medya
hesapları” incelenmiştir. Sonuç olarak TRT World’un dünyaya İngilizce yayın yaparak
Türkiye’nin kamu diplomasisi stratejisinin unsurlarından birisi olduğu ve Türkiye’nin
uluslararası yayıncılık çabalarının tamamlayıcı bir aktörü olduğu sonucuna varılmıştır.
Reklamlarda Toplumsal Sınıf: Otomobil Reklamları Üzerinden Bir Söylem Analizi
Authors: AYVAZ Süheyla , LİVBERBER Tuba
Published: July 2019

Toplumsal sınıf; toplum içerisindeki bireylerin ekonomik, sosyal ve kültürel
iyeliklerinin nicel durumuna göre hiyerarşik olarak bölünmesine/gruplaşmasına
işaret etmektedir. Medya da kültürel ürünler aracılığıyla bu grup çıkarlarının
meşrulaştırılması ve desteklenmesine yardımcı olan fikir ve inançları simgeleyen
ideolojik söylemleri inşa etmektedir. Reklam metni bu bağlamda tüketiciye özerk
nesneler olarak seslenmekte ve sahte ihtiyaçlara kültürel yan anlamlar ekleyerek
nesneleri simgesele indirgemektedir. Böylece reklamlardaki kodlar aracılığıyla belirli
bir yaşam tarzı ve dolayısıyla sınıf atlama ya da sınıfsal bir konuma sahip olma pratiği
üretilmekte ve yeniden üretilmektedir. Bu ana eksenden yola çıkan araştırmada,
ideolojik yaklaşım çerçevesinde reklam metinlerinin çözümlenmesi amaçlanmıştır.
Renault, Jetta ve Opel’in toplumsal sınıf temalı birer reklam filmi araştırmanın
inceleme nesnesi olarak belirlenmiştir. Reklam metinleri, Van Dijk’ın eleştirel söylem
analizi yöntemi kullanılarak çözümlenmektedir. Çalışma sonucunda analiz edilen
reklam filmlerinin senaryo açısından öncelikli temasının üst orta sınıf vurgusu
olduğu görülmüştür. Bunun yanı sıra karakterlerin giyiminden konumlanışına,
mekanların düzenlenmesinden kullanılan nesnelere kadar bütünüyle aynı sınıfa ait
yaşam tarzı betimlemelerinin yer aldığı gözlemlenmiştir.
Sanal Üretim ve Sanal Tüketim Bağlamında Bilgisayar Oyunları ve Boş Zaman Kavramı: Farmvılle Örneği
Authors: TAYDAŞ Onur , KARAKOÇ Enderhan
Published: July 2019

Bireylerin zamanlarının büyük bir kısmını kitle iletişim araçlarıyla geçirdikleri bilindiği için,
kitle iletişim araçlarına ayırdıkları zamanın onların hayatlarını ne yönde etkilediğini konu
edinen araştırmalar literatürde fazlasıyla bulunmaktadır. Son zamanlarda ise bu araştırmalara
ek olarak bireylerin sosyal medyaya ayırdıkları zamanı ve bu zamanın bireylerin yaşantısına
etkisi de yeni yeni incelenmeye başlanmıştır. Bu konuyla ilgili literatüre bakıldığında sıklıkla
bireylerin sosyal medyada geçirdikleri zamanın ne derece etkili olduğu, ne kadar süreyi sosyal
ağlara ayırdıkları ya da sosyal ağları neden bu kadar sık kullandıkları ayrı ayrı sorgulanmaktadır.
Bilindiği üzere sosyal ağlarda insanların diğer insanları takip etmelerinin temel amaçlarından
birisi bir şeylerden haberdar olmaktır. Fakat aynı zamanda aynı bireyler sosyal ağları oyunlar
oynamak içinde kullanmaktadır. Üyelerine farklı sebepler sunmanın yolunu arayan sosyal
ağlar eğlence özelinde sundukları bu oyunlar ile isteklerine ulaşmış bulunmaktadır. Bireylerin
başlıca sosyal ağlarda neden oyun oynamayı tercih ettiklerini anlamaya yönelik hazırlanan bu
çalışmada bireylerin, sanal dünyada üretim yapmayı neden tercih ettikleri, boş zamanlarını
neden bu oyunla geçirdikleri incelenmiştir. Sanal üretim, sanal dağıtım ve sanal tüketim
üzerine kurulu mantığıyla dünyada en fazla oynanan oyunlardan birisi olan FarmVille bu
kapsamda çalışma için seçilmiş, bu oyunu oynayanlar çalışmanın eksenine dahil edilmiştir.
Ayrıca çalışmada ölçme aracı olarak ankete başvurulmuştur. Araştırmaya katılan bireylerin,
FarmVille oyununu oynadıkları zamanlar incelendiğinde katılımcılardan erkek ve kadınların
yaklaşık %80’ninin günlük iki saatlerini bu oyuna ayırdıkları belirlenmiştir. Dolayısıyla modern
insanın en büyük sorunu olarak dile getirilen zamanın belli bir kısmının oyunlarda geçirilmesi,
bireylerin rahatlamaya ve sorumluklardan, sorunlardan kaçmaya ne kadar ihtiyaç duyduklarını
göstermektedir. Araştırmada elde edilen sonuçlar kısaca değerlendirildiğinde; katılımcıların
çoğunlukla sosyalleşme, boş zaman değerlendirme, rahatlama, sorunlardan ve sorumluklardan
kaçma gibi sebeplerle oyunu tercih ettikleri görülmüştür.
THE REGIONAL DEVELOPMENT OF JAPAN IS AN IMPORTANT OBJECT OF SOCIO-GEOGRAPHICAL RESEARCH
Authors: Chychkan Anastasiia
Published: July 2019

The purpose: to study the Japanese experience of regional development and planning in the context of sustainable development, which is an important objective of socio-geographical research.

Methods. Were used methods of analysis political geography, regional and international studies.

Results, scientific novelty and the practical significance. The concept of development, modern interpretations of regional development and regional policy, preconditions and grounds for introducing in Japan a new model of development (sustainable regional development), the modern territorial organization of Japan were considered in the paper. Were analyzed the regional planning of Japan in retrospective view and modern trends. To research the experience of such highly developed countries like Japan - is an opportunity to look into the future, to highlight the best practices of the regional and territorial development and to adopt this experience in Ukraine.
ANALYSIS AND OPTIMIZATION DIRECTIONS FOR GASTRONOMIC TOURISM DEVELOPMENT IN THE CARPATHIAN REGION
Authors: Savchyn Halyna , Iuras Iuliia
Published: July 2019

The purpose of the study is to analyze gastronomic festivals in the Carpathian region and to develop the direction for optimizing the gastronomic tourism development.

Methods. The authors used the following research methods: analysis, comparison, statistical, etc.

Results. The article analyzes the statistical indicators of the gastronomic tourism development in the Carpathian region. The dynamics of gastronomic festivals, their seasonality and territorial affiliation were determined. A schematic map of gastronomic festivals of the Carpathian region was developed. The optimization directions for gastronomic tourism development in the region were proposed.

Scientific novelty. Complex analysis of gastronomic festivals of the Carpathian region was done according to different indicators. “Carpathian Mushrooms Festival” was developed as a way to optimize the development of gastronomic tourism in the region.

Practical significance. The results of the study can be used in the further planning of gastronomic tourism development in the Carpathian region and the corrections of the tourist policy of the region.
İLKOKUL 4. SINIF ÖĞRENCİLERİNİN OKUMA MOTİVASYONLARI İLE OKUDUĞUNU ANLAMA BECERİLERİ ARASINDAKİ İLİŞKİ VE BU KONUYA YÖNELİK ÖĞRETMEN GÖRÜŞLERİ
Authors: Batmaz Onur , Erdoğan Özge
Published: July 2019

Bu
araştırma, ilkokul 4. sınıf öğrencilerinin okuma motivasyonları ile okuduğunu
anlama becerileri arasındaki ilişkinin belirlenmesi ve bu konuya ilişkin
öğretmen görüşlerinin incelenmesi amacıyla yapılmıştır. Nicel ve nitel
araştırma yaklaşımlarının bir arada kullanıldığı karma yöntem ile yürütülen
araştırmanın çalışma grubunu, Yozgat il merkezinde yer alan üç ilkokulda
bulunan 216 ilkokul dördüncü sınıf öğrencisi ile bu okullarda görev yapan 10
sınıf öğretmeni oluşturmaktadır. Araştırmanın katılımcıları belirlenirken kolay
ulaşılabilir durum örnekleme yöntemi kullanılmıştır. Araştırmanın verileri,
Yıldız (2010) tarafından yapılan “Okuma Motivasyonu Ölçeği”, Batmaz (2017)
tarafından hazırlanan “Okuduğunu Anlama Başarı Testi” ve araştırmacılar
tarafından hazırlanan yarı yapılandırılmış görüşme formu ile toplanmıştır. Elde
edilen veriler SPSS 21.00 programı ve betimsel analiz ile analiz edilmiştir.
Araştırmanın sonucunda, ilkokul dördüncü sınıf öğrencilerinin okuma
motivasyonlarının yüksek ve okuduğunu anlama becerilerinin ise orta düzeyde
olduğu bulunmuştur. Ayrıca ilkokul dördüncü sınıf öğrencilerin okuma motivasyonları
ile okuduğunu anlama becerileri arasında pozitif yönde çok yüksek düzeyde
anlamlı bir ilişkinin olduğu sonucuna ulaşılmıştır.
Prospects of using cystatin c as an early predictor of diabetic nephropathy
Authors: Borovik Natalia V. , Yarmolinskaya Maria I. , Glavnova Olga B. , Tiselko Alyona V. , Suslova Svetlana V. , Shilova Ekaterina S.
Published: July 2019

Hypothesis/aims of study. Using early non-invasive markers of diabetic nephropathy (DN) in clinical practice is important to early start of nephroprotective therapy and leads to improving the quality of life, while decreasing disability and mortality of diabetic patients. The aim of the study was to estimate the potential of using serum cystatin C and glomerular filtration rate (GFR) calculated by CKD-EPIcys and CKD-EPIcr-cys equations for an early diagnosis of DN in type 1 diabetic (T1D) women who were planning pregnancy or were in the I trimester of pregnancy.
Study design, materials, and methods. 47 T1D women were examined, of whom 25 individuals were pregnant and 22 ones were planning pregnancy. In all patients, glycated hemoglobin and serum cystatin C levels were determined, GFR was estimated by the creatinine clearance test, MDRD, CKD-EPIcr, CKD-EPIcys, and CKD-EPIcr-cys equations, with diabetes training done.
Results. The pregnant group and the planning pregnancy group were distinguished by glycated hemoglobin (p = 0.001), serum creatinine (p = 0.001), and GFR estimated by the creatinine clearance test (р = 0.017), CKD-EPIcr (р = 0.005), and CKD-EPIcr-cys (р = 0.046) equations. There was no difference in urinary creatinine, serum cystatin C, and GFR estimated by CKD-EPIcys equation and daily urinary protein excretion between the study groups. Most pregnant women (87.5%) were in stage C1 and only 12,5% in stage C2 as determined by estimated GFR using the CKD-EPIcr formula, which was significantly different compared to the planning pregnancy group, where the percentage of women in stages C1 and C2 was comparable (р = 0.002). In addition, most pregnant patients were in stage C1, while most of the patients planning pregnancy were referred to stage C2 by GFR estimated by CKD-EPIcysequation. Stage C3a was diagnosed in the both study groups only when CKD-EPIcys equation for GFR estimation was used. Most women from both groups were in stage C1 when GFR was estimated by the creatinine clearance test, the percentage ratio of patients in stages C1 and C2 in both groups being comparable.
Conclusion. Our results demonstrated that serum cystatin C and GFR estimation by CKD-EPIcys equation could improve nephropathy diagnostic accuracy among T1D patients with a normal serum creatinine level and intact GFR based on creatinine level.
The role of growth factors in the pathogenesis of endometriosis
Authors: Florova Margarita S.
Published: July 2019

Endometriosis is a chronic inflammatory hormone-dependent disease characterized by abnormal proliferation in the endometrium, nerves, blood vessels, fibroblasts, etc. and accompanied by immunological disorders. Growth factors are an important part of the mechanisms that underlie intercellular communication, auto- and paracrine regulation. This literature review presents data on abnormal expression of growth factors in patients with endometriosis, relationship of growth factors and hormonal status in normal and endometrial tissues, and the supposed role of growth factors in the pathogenesis of the disease.
Caracterización de los modelos pedagógicos y su pertinencia en una educación contable crítica
Authors: Gómez Contreras Jennifer Lorena , Monroy Bermúdez Liliana de Jesús , Bonilla Torres Cristian Alberto
Published: July 2019

En el presente documento se identifican los elementos, los actores y los intereses presentes en los modelos pedagógicos más relevantes en la literatura académica, en contraste con lo aplicado en la educación contable, con el fin de fundamentar un modelo pedagógico tendiente a una formación contable crítica, analítica, activa y propositiva. Para ello, se analizan las teorías y los modelos pedagógicos a través de los autores más citados por investigadores que describen las características de los procesos de aprendizaje desde distintas ciencias sociales, y en el ámbito de la educación contable se revisan artículos, libros y tesis que abordan las necesidades sociales del ejercicio profesional contable enfocando la revisión en las investigaciones dadas con posterioridad a la crisis económica del 2002 en Estados Unidos y aquellas publicaciones emitidas por organizaciones multilaterales que buscan guiar criterios de confiabilidad y comparabilidad de la profesión y la información contable a nivel internacional. Se concluye que los modelos pedagógicos que podrían tener un mayor impacto en la generación de contadores críticos, analíticos, proactivos y propositivos, son aquellos que otorgan un rol principal al estudiante y se enfocan en la formación de individuos que permitan el desarrollo social y económico de su entorno.
Pregnancy induced hypertension: lipid peroxidation and antioxidant status
Authors: Shah Aaliya , Rashid Adila , Khan Mosin S. , Parvez Tabassum , Kaisar Mir , Mudassar Syed
Published: July 2019

Background: Pregnancy is a stressful condition accompanied by a high energy demand and increased oxygen requirement. Oxidative stress has been recognized as a significant factor linked to hypertension. Elucidation of anti-oxidant cascade in patients with pregnancy induced hypertension (PIH). can give insights about the oxidative stress and lead to better management of the condition. It was a prospective case control study to elucidate the parameters of oxidative stress in patients with PIH.Methods: Levels of Malondialdehyde (MDA), superoxide dismutase (SOD) and catalase (CAT) were eludidated using enzyme linked immunosorbent assay (ELISA) in hypertensive mothers and their age matched pregnant and non-pregnant controls to determine the lipid peroxidation and oxidative stress.Results: A total of four hundred and twenty study subjects were enrolled in the study. Malondialdehyde levels from mothers with hypertension were significantly higher than their age matched pregnant controls. The results indicate that oxidative stress induced by pregnancy induced hypertension manifests as increased lipid peroxidation. Conclusion: There is a decrement in anti-oxidant status reflecting the ineffective scavenging of reactive oxygen species resulting in oxidative damage and tissue injury.
Clinico-hematological profile of anaemia in adolescent girls in a tertiary care hospital of North India
Authors: Sharma Manoj Kumar , Parashar Preeti , Jain Neelima
Published: July 2019

Background: Anaemia in adolescent girls leads to foetal morbidity and mortality in future. The current study was done with the aim to study the clinico-haematological profile of anaemia in adolescent girls in a tertiary care hospital of North India.Methods: An observational study was conducted among 50 adolescent girls with anaemia (Hb <12 g/dl) in the Department of Medicine in collaboration with Department of Pediatrics and Department of Haematology at VMMC and Safdar-jang Hospital, New Delhi. Detailed previous history of the patients was collected. Blood samples were collected from all the patients and analysed for hematological parameters. Data were analysed statistically and p values less than 0.05 was considered significant.Results: The prevalence of anaemia was common in the patients of age group of 15-19 years (58%). The common symp-tom observed was fatigue (82%). Pallor was the common sign noticed in 66% patients. Majority of the patients with anaemia belongs to upper lower class (52%). Mean value of haemoglobin was high (7.80±1.22) in microcytic hypo-chromic anaemia compared to other types of anaemia. Serum iron levels were low in both microcytic and dimor-phic group but the difference was statistically not significant (p=0.43). Serum vitamin B12 levels were low in mac-rocytic and dimorphic anaemia and the difference was statistically significant (p=0.001).Conclusions: This study showed that nutritional deficiency anaemia was more prevalent in adolescent girls of age group between 15-19 years of upper lower socioeconomic status. Nonspecific symptoms like fatigue and weakness should not be ignored in the adolescent girls as they could be important indicators towards incidence of anaemia in these patients.
Preservasi Konten Lokal di Perpustakaan Perguruan Tinggi (Studi Kasus Medical Knowledge Center UPN Veteran Jakarta)
Authors: Saputra Dwi Fajar
Published: July 2019

The college library is the center in the running of the wheel of disseminating knowledge. One of the collections found in the college library is local content. Local content has a variety of types, among others, student writings and lecturers’ research results. Medical Knowledge Center as a center for depositing local content academicians of the Faculty of Medicine UPN Veteran Jakarta strives to facilitate the existing local content to be more optimally utilized. This research was conducted to determine the application of local content preservation in the Medical Knowledge Center in terms of processes and benefits. The method used is descriptive qualitative. Stages are carried out by identification, selection and decision making. Conclusion Local content becomes more organized, the value of existing knowledge is maintained and extends dissemination.Perpustakaan perguruan tinggi merupakan pusat dalam berjalannya roda penyebarluasan pengetahuan. Salah satu koleksi yang terdapat di Perpustakan perguruan tinggi adalah konten lokal. Konten lokal memiliki beragam jenis antara lain hasil karya tulis Mahasiswa dan hasil penelitian Dosen. Medical Knowledge Center sebagai pusat deposit konten lokal sivitas akademika Fakultas Kedokteran UPN Veteran Jakarta berusaha untuk memfasilitasi agar konten lokal yang ada menjadi lebih optimal pemanfaatannya. Penelitian ini dibuat untuk mengetahui penerapan preservasi konten lokal di Medical Knowledge Center dari segi proses dan manfaat. Metode yang digunakan dengan deskriptif kualitatif. Tahapan dilakukan dengan identifikasi, seleksi dan pengambilan keputusan. Kesimpulan konten lokal menjadi lebih tertata, nilai pengetahuan yang ada tetap terjaga dan memperluas diseminasi.
Investigating the effect of extended high-frequency hearing loss on duration pattern sequence test
Authors: Farahani Athareh , Farahani Saeid , Rouhbakhsh Nematollah , Zamiri Abdollahi1 Farzaneh , Bolandi Masoud
Published: July 2019

Background and Aim: Temporal processing is affected in people exposed to occupational noi­se. The primary goal of this study was to eva­luate the temporal processing of people exposed to occupational noise of more than 85 dB A but have not experienced clinically significant chan­ges at hearing thresholds at conventional frequ­encies.
Methods: A comparison between groups were designed using individuals exposed to occupa­tional noise (n = 15 as the case group) and non-exposed individuals (n = 16 as the control gro­up). Two groups were age-matched (p < 0.05). The extended high-frequency audiometric thre­sholds and temporal processing system were evaluated through a duration pattern sequence test. Finally, the correlation between the exten­ded high-frequency hearing thresholds and the duration pattern test scores was investigated.
Results: The case group had significantly high­er hearing thresholds than the control group at 14, 15, and 16 kHz (p < 0.05). Although in other frequencies, the mean hearing thresholds in the case group was higher than the control group, the difference was not significant. Also, the case group had significantly lower duration pattern sequence scores than the control group in the right (p = 0.02) and the left ears (p = 0.03). There was no correlation between extended high-frequency hearing thresholds and duration pattern sequence test scores.
Conclusion: In people exposed to occupational noise, both extended high-frequency thresholds and temporal processing in lower frequency ran­ges (with normal hearing thresholds) are inter­rupted.
The regulatory role of cystatin C in autophagy and neurodegeneration
Authors: Korolenko T. A. , Shintyapina A. B. , Pupyshev A. B. , Akopyan A. A. , Russkikh G. S. , Dikovskaya M. A. , Vavilin V. A. , Zavjalov E. L , Tikhonova M. A. , Amstislavskaya T. G.
Published: July 2019

Autophagy is a dynamic cellular process involved in the turnover of proteins, protein complexes, and organelles through lysosomal degradation. It is particularly important in neurons, which do not have a proliferative option for cellular repair. Autophagy has been shown to be suppressed in the striatum of a transgenic mouse model of Parkinson’s disease. Cystatin C is one of the potent regulators of autophagy. Changes in the expression and secretion of cystatin C in the brain have been shown in amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s diseases, and in some animal models of neurodegeneration, thus proving a protective function of cystatin C. It has been suggested that cystatin C plays the primary role in amyloidogenesis and shows promise as a therapeutic agent for neurodegenerative diseases (Alzheimer’s and Parkinson’s diseases). Cystatin C colocalizes with the amyloid β-protein in the brain during Alzheimer’s disease. Controlled expression of a cystatin C peptide has been proposed as a new approach to therapy for Alzheimer’s disease. In Parkinson’s disease, serum cystatin C levels can predict disease severity and cognitive dysfunction, although the exact involvement of cystatin C remains unclear. The aim: to study the role of cystatin C in neurodegeneration and evaluate the results in relation to the mechanism of autophagy. In our study on humans, a higher concentration of cystatin C was noted in cerebrospinal fluid than in serum; much lower concentrations were observed in other biological fluids (intraocular fluid, bile, and sweat). In elderly persons (61–80 years old compared to practically healthy people at 40–60 years of age), we revealed increased cystatin C levels both in serum and intraocular fluid. In an experiment on C57Bl/6J mice, cystatin C concentration was significantly higher in brain tissue than in the liver and spleen: an indication of an important function of this cysteine protease inhibitor in the brain. Using a transgenic mouse model of Parkinson’s disease (5 months old), we demonstrated a significant increase in osmotic susceptibility of brain lysosomes, depending on autophagy, while in a murine model of Alzheimer’s disease, this parameter did not differ from that in the appropriate control.
Porejestracyjne badania bezpieczeństwa produktów leczniczych w systemie "pharmacovigilance"
Authors: Rabiega-Przyłęcka Agnieszka
Published: July 2019

Celem artykułu jest przedstawienie prawnych uwarunkowań jednego z elementów systemu pharmacovigilance (bezpieczeństwa farmakoterapii) – porejestracyjnych badań bezpieczeństwa produktów leczniczych. Analizie poddano wymogi oraz zasady prowadzenia badań bezpieczeństwa produktów leczniczych po wydaniu pozwolenia na dopuszczenie ich do obrotu w świetle obowiązujących przepisów prawnych, w szczególności ustawy z dnia 6 września 2001 r. Prawo farmaceutyczne.
Congenital Central Hypoventilation Syndrome: A Case-Based Learning Opportunity for Neonatal Clinicians
Authors: Fisher Michelle , Smeiles Chelsey , Jnah Amy J. , Ruiz Michelle Elias , Difiore Tina , Sewell Kerry
Published: July 2019

Congenital central hypoventilation syndrome (CCHS) is a rare and sporadic neurocristopathy characterized by alveolar hypoventilation and autonomic nervous system dysfunction. CCHS manifests quickly after birth, initially as respiratory distress. Mortality risk is estimated at 38 percent, with a median age of death of three months of age. A timely and accurate diagnosis is critical. Genetic testing for PHOX2B gene mutations is necessary to confirm the diagnosis; however, laboratory turnaround time often imposes an additional 7–14-day waiting period on an often anxious family. Neonatal clinicians should recognize that families require disease-specific education, emotional support, and time to rehearse daily caregiving in preparation for discharge. Therefore, this article presents the key clinical, pathophysiologic, and diagnostic factors, as well as a discussion of discharge needs. A case report of an infant, born to parents with no known history of CCHS, is included as a case-based learning opportunity for readers.
Pharmacotherapy for the Prevention of Bronchopulmonary Dysplasia: Can Anything Compete with Caffeine and Corticosteroids?
Authors: McPherson Christopher
Published: July 2019

Bronchopulmonary dysplasia (BPD) is a morbidity of prematurity with implications for respiratory and neurologic health into adulthood. Multiple risk factors contribute to the development of BPD leading to examination of various prevention strategies. The roles of systemic corticosteroids and caffeine have been addressed by the American Academy of Pediatrics. The place in therapy of other agents commonly utilized in clinical practice remains unclear. Inhaled nitric oxide has been the subject of numerous large, randomized controlled trials in preterm infants. Despite sound rationale, these trials have largely failed to document benefit, suggesting a limited role for inhaled nitric oxide therapy in the preterm population. In contrast, intramuscular vitamin A has been documented to reduce the incidence of BPD in randomized trials. However, the invasiveness and the sporadic availability of this therapy have led to decreased utilization. All macrolide antibiotics do not appear to have a similar impact on the incidence of BPD; however, azithromycin administered to infants colonized withUreaplasmamay have impact. Questions remain about the optimal dosing approach and long-term safety of this intervention. Finally, diuretic therapy is widely used in clinical practice despite significant toxicities and limited data supporting a role in BPD prevention. Taken together, available data suggest that caffeine and selective use of corticosteroids remain the mainstays of pharmacologic BPD prevention.
Introduction to the Special Issue: Challenges in Treating Obsessive-Compulsive Disorder With Cognitive-Behavioral Therapy
Authors: Wheaton Michael G.
Published: July 2019

Cognitive-behavioral therapy (CBT) is a recommended treatment for obsessive-compulsive disorder (OCD). CBT offers specific interventions with demonstrated efficacy, including both cognitive therapy and exposure and ritual prevention (ERP). Yet, implementing these techniques with individual patients can present clinical challenges. In this special issue, expert clinicians and researchers present cases in which they addressed some common challenges in implementing CBT for OCD, including comorbid depression, poor insight, and family accommodation of symptoms in pediatric OCD. Other papers present how CBT can be tailored to specific OCD manifestations, including post-partum OCD, taboo thoughts, and relationship OCD. Other authors detail how they have augmented standard ERP with additional treatment techniques to maximize outcomes. These articles present a diverse set of case histories and specific treatment techniques that illustrate ways to maximize the effectiveness of CBT for OCD, serving as a useful guide for clinicians in practice and highlighting areas for future research.
Comorbidity, Parental Psychopathology, and Accommodation in the Treatment of Pediatric Obsessive-Compulsive Disorder: A Case Study
Authors: Wadkins Melanie J. , Gordon Elizabeth
Published: July 2019

This article discusses the treatment of a young person with obsessive-compulsive disorder (OCD) characterized primarily by symptoms of physical and mental contamination, as well as religious obsessions. The treatment was complicated by several factors that will be reviewed and addressed. First, this client had a comorbid diagnosis of attention-deficit/hyperactivity disorder. Second, the young client's mother was also diagnosed with OCD and had a significantly anxious presentation. This impacted treatment in two primary ways. One important way treatment was complicated was that the client frequently attempted to manage her mother's emotions by underreporting her own distress at times. The other implication of the mother's diagnosis was that it became difficult to involve her in the treatment of her daughter and reduce her accommodation of her daughter's symptoms. The manner in which these complicating factors were addressed in the successful treatment of this client by adapting evidence-based practice will be presented as a guide for clinicians facing similar challenges.