bluuebunny/crossref_metadata_2025 huggingface dataset:
Physiological and chemical performance of the Flame seedless grapevine cultivar in the presence of Paulsen 1103 as the interstock
Authors: Fayek Mohamed Ahmed , Ali Amr Ebrahim Mohamed , Rashedy Ahmed Abdelhady
Published: April 2022

ABSTRACT Interstock is commonly used in deciduous fruit trees as a sustainable strategy to reduce the vigor of the scion associated with the high quality of fruits. In this study, we tested the effect of Paulsen 1103 (Vitis berlandieri x Vitis rupestris) as interstock on the grafting success, growth, and the physiological and chemical parameters of Flame seedless (Vitis vinifera) grapevine grafted onto Freedom (Vitis champinii x 1613C) and Paulsen 1103 rootstocks. This study was conducted over two seasons (2019 and 2020). The results indicated that direct grafting on the Paulsen 1103 rootstock recorded the highest grafting success percentage. Moreover, the grafting success percentage increased significantly when Paulsen 1103 was used as interstock between Flame seedless and Freedom rootstock (FI/P/Fr) compared to the grafting success without Paulsen 1103 interstock (FI/Fr). Also, using Paulsen 1103 as interstock between Flame seedless scion and Freedom rootstock (FI/P/Fr) significantly reduced the morphological parameters (shoot length, leaf area and the dry weight of shoots and roots) and physiological parameters of leaf (relative water content, transpiration rate, and stomatal conductance) but significantly increased the leaf chemical content (peroxidase activity, total phenols, total proline, and total soluble sugar content) compared to values of the parameters measured in Flame seedless grafted onto Freedom rootstock (FI/Fr). Peroxidase activity could be used for predicting the degree of compatibility in grapevine grafts. This study suggested that the effect of Paulsen 1103 interstock on the vegetative growth of scion is correlated with its effect on chemical content and physiological responses of the scion.
Diferenças salariais e discriminação por gênero e cor nos setores agrícola e não agrícola do Brasil nos anos de 2004, 2012, 2015 e 2019
Authors: Catelan Davi Winder , Fonseca Maylisson Rodrigo , Bacchi Matheus Demambre , Alves Alexandre Florindo
Published: April 2022

Resumo O objetivo deste estudo é analisar as diferenças salariais entre homens e mulheres e entre brancos e não brancos ocupados nos setores agrícola e não agrícola do Brasil nos anos de 2004, 2012, 2015 e 2019. Para isso, foram utilizados os dados da PNAD para os anos de 2004 e 2015 e os dados da PNADC para 2012 e 2019, fornecidos pelo IBGE. O método de Firpo et al. (2007) foi empregado para decompor os diferenciais ao longo da distribuição de salários. Verificou-se que, nos dois setores e anos considerados, as diferenças salariais por gênero foram maiores no 10o quantil da distribuição, em razão, sobretudo, do efeito estrutura salarial. Já os diferenciais de salários entre brancos e não brancos foram maiores no 90o quantil, em função do elevado déficit dos não brancos nas características produtivas (efeito composição). Entre 2004 e 2015, houve crescimento das diferenças salariais entre os grupos inseridos no setor agrícola, particularmente, nos 10o, 25o e 50o quantis, enquanto no setor não agrícola houve redução. Entre 2012 e 2019, ocorreu redução das diferenças salariais por gênero nos dois setores e aumento das diferenças por cor. Por fim, comprovou-se que os diferenciais de salários foram maiores no setor agrícola.
Implementación de pagos por servicios ambientales en la Cuenca del río Cali, Colombia: una mirada desde los sistemas socioecológicos
Authors: Arias-Arévalo Paola , Pacheco-Valdés Nicol
Published: April 2022

Resumen: En Colombia –un país bioculturalmente diverso y con profundas inequidades– se proyecta ampliar el uso de pagos por servicios ambientales (PSA). Esta investigación identifica los factores que influenciaron la implementación de uno de los primeros PSA desarrollados en Colombia, durante 2009-2014, en la cuenca del río Cali. Se aplicó el marco de sistemas socioecológicos (SSE), un marco que ha sido escasamente aplicado al análisis de PSA. Se realizaron 15 entrevistas a expertos y participantes del PSA y se revisó información secundaria asociada al programa. A través de un análisis de contenido, se identificó que influenciaron positivamente la implementación del PSA: la calidad y la importancia atribuida a los servicios hídricos; la participación y liderazgo de organizaciones no gubernamentales y comunitarias; y la convergencia del programa con cosmovisiones y valores proambientales. Algunos factores con influencia negativa fueron: conflictos entre actores comunitarios; reglas nacionales asociadas a la tenencia de la tierra; y los altos costos de oportunidad asociados al uso del suelo que enfrentan pequeños propietarios. El marco de los SSE contribuye a analizar la multiplicidad de resultados emergentes –ecológicos, sociales, económicos y políticos– de la implementación del PSA, los cuales frecuentemente son omitidos en diseños con énfasis en aspectos técnicos.
Review of the armoured catfish genus Hypostomus (Siluriformes: Loricariidae) from the Parnaíba River basin, Northeastern Brazil, with description of a new species
Authors: Lustosa-Costa Silvia Yasmin , Ramos Telton Pedro Anselmo , Zawadzki Cláudio Henrique , Lima Sergio Maia Queiroz
Published: April 2022

Abstract The species of Hypostomus from the Parnaíba River basin were reviewed through molecular and morphological analysis. Five species were found in the basin, including a new species herein described. The distribution of H. pusarum was expanded to this basin, and a closely related species was recorded (H. aff. pusarum), also the presence of H. johnii and H. vaillanti was confirmed. The new species is distinguished from most congeners by its large number of premaxillary and dentary teeth, a wide dental angle of 115° to 135°, presence of a rounded dark spots on a lighter background and anteromedial region of the abdomen depleted of plaques (vs. anteromedial region of the abdomen covered by platelets and odontodes in H. johnii, H. pusarum, H. aff. pusarum and H. vaillanti). Furthermore, an identification key of the species from the Maranhão-Piauí ecoregion and maps with the geographic distribution of these species are presented. The species of Hypostomus in the Parnaíba River basin have different geographic distributions, suggesting different niches or geographical barriers, providing an opportunity for ecological and evolutionary studies.
O ENSINO DA ARTE NA ALDEIA E NA ESCOLA INDÍGENA: CONHECIMENTOS TRADICIONAIS E CONHECIMENTOS CONTEMPORÂNEOS
Authors: Kuĩ Rasu Inu Bake Huni , Araujo Hanna Talita Gonçalves Pereira de
Published: April 2022

RESUMO O ensino da arte faz parte do currículo das escolas indígenas brasileiras, mas o indígena tem sua própria forma de ensinar e aprender arte na aldeia, sem precisar de livros ou de outro material didático convencional, pois a arte está presente em seu dia a dia, uma vez que todo indígena é artista. Este artigo apresenta os modos de ensinar e aprender arte considerando os conhecimentos tradicionais do povo Huni Kuĩ da Terra Indígena Kaxinawá de Nova Olinda. Será enfatizado como os indígenas ensinam arte dentro e fora da escola, nas aldeias dessa terra, sob o ponto de vista do professor indígena.
AULAS DE ARTE NO CAMPO DE TEREZÍN E A ATUAÇÃO DE FRIEDL DICKER-BRANDEIS
Authors: Reily Lucia
Published: April 2022

RESUMO O presente texto apresenta um estudo documental sobre a atuação da austríaca Friedl Dicker-Brandeis, artista plástica e professora de arte encarcerada em Terezín, um campo de concentração montado pelo regime nazista perto de Praga. Contextualiza o campo como pano de fundo e discute o ensaio deixado pela professora sobre os seus objetivos e modos de pensar o ensino de arte para que possamos compreender como emergiu, em meio aos escombros de vida, um espaço de criação artística para crianças e adolescentes.
A FORMAÇÃO DOS ALUNOS DE ARTE PARA ATUAR EM CONTEXTOS PLURAIS
Authors: Pizza Dulcinéia Galliano
Published: April 2022

RESUMO Este texto apresenta resultados de um estudo documental sobre relatórios da prática de alunos da Licenciatura em Artes Visuais, com relatos de experiência que fundamentam escolhas metodológicas, em um espaço socializado sobre a diversidade de campos de atuação para o professor de arte, promovendo um campo reflexivo sobre decisões pedagógicas, evidenciando possibilidades de leitura dos contextos sociais em espaços de ensino não formais, atendendo um público diverso e hetorogêneo.
A RING WITH MAGICAL POWERS: DUTCH ARTISTS WITH INTELLECTUAL DISABILITIES JOIN THE FASHION PROJECT OUTSIDERWEAR
Authors: Vogelaar Josien
Published: April 2022

ABSTRACT This article presents a collaborative project carried out with these outsider artists and a group of young Dutch creatives. The project initiated by the cultural entrepreneur Jan Hoek consists of creating a fashion label Outsiderwear, in which young creatives, mostly fashion designers, were matched with outsider artists from Outsider Art Studios in Amsterdam; working together, the pair developed a collection. The idea was to establish a structural collaboration between professional creatives and outsider artists. Data is presented using interviews in order to construct a case study.
Fairness in Influence Maximization through Randomization
Authors: Becker Ruben , D’Angelo Gianlorenzo , Ghobadi Sajjad , Gilbert Hugo
Published: April 2022

The influence maximization paradigm has been used by researchers in various fields in order to study how information spreads in social networks. While previously the attention was mostly on efficiency, more recently fairness issues have been taken into account in this scope. In the present paper, we propose to use randomization as a mean for achieving fairness. While this general idea is not new, it has not been applied in this area.

Similar to previous works like Fish et al. (WWW ’19) and Tsang et al. (IJCAI ’19), we study the maximin criterion for (group) fairness. In contrast to their work however, we model the problem in such a way that, when choosing the seed sets, probabilistic strategies are possible rather than only deterministic ones. We introduce two different variants of this probabilistic problem, one that entails probabilistic strategies over nodes (node-based problem) and a second one that entails probabilistic strategies over sets of nodes (set-based problem). After analyzing the relation between the two probabilistic problems, we show that, while the original deterministic maximin problem was inapproximable, both probabilistic variants permit approximation algorithms that achieve a constant multiplicative factor of 1 − 1/e minus an additive arbitrarily small error that is due to the simulation of the information spread. For the node-based problem, the approximation is achieved by observing that a polynomial-sized linear program approximates the problem well. For the set-based problem, we show that a multiplicative-weight routine can yield the approximation result.

For an experimental study, we provide implementations of multiplicative-weight routines for both the set-based and the node-based problems and compare the achieved fairness values to existing methods. Maybe non-surprisingly, we show that the ex-ante values, i.e., minimum expected value of an individual (or group) to obtain the information, of the computed probabilistic strategies are significantly larger than the (ex-post) fairness values of previous methods. This indicates that studying fairness via randomization is a worthwhile path to follow. Interestingly and maybe more surprisingly, we observe that even the ex-post fairness values, i.e., fairness values of sets sampled according to the probabilistic strategies computed by our routines, dominate over the fairness achieved by previous methods on many of the instances tested.
Brazilian megacities: quantifying the impacts of the Brazilian urban mobility policy
Authors: Fontoura Wlisses Bonelá , Ribeiro Glaydston Mattos , Chaves Gisele de Lorena Diniz
Published: April 2022

Brazil has several problems related to urban mobility. These issues are most evident in big cities where the territorial extension and the complex activities developed in urban space make transportation planning difficult. Therefore, Brazilian cities face challenges to implement the Brazilian Urban Mobility Policy (BUMP) requirements. Since this enactment, in 2012, several studies have been developed to evaluate the impacts of the mitigations proposed by this law. Among these studies, a proposition of a system dynamics (SD) model to assess the effects of this policy stands out. This model allows verifying the impact of different BUMP mitigation measures (individually and together). Therefore, this paper aims to obtain and to compare the results of the application of this SD model in two Brazilian megacities: Rio de Janeiro and São Paulo. The results show the importance of BUMP implementation to reduce the negative externalities of transportation systems and improve their efficiency. However, the effects of this policy are not the same for the two megacities.
Att skapa historiska sammanhang: Exemplet Thomas Mores Utopia
Authors: Rodell Magnus
Published: April 2022

This chapter argues that the concept of context as it is commonly used in historical textbooks for explaining historical phenomena and events is problematic as it implies an historically fixed structure. Instead, the chapter suggests meaning-making contexts, and seeks to render visible the activity involved in creating historical contexts and to demonstrate that it is always the historian who produces these meaning-making contexts. Implicitly or explicitly, historical textbooks produce and use different types of contexts. The chapter explores nine different textbooks on Thomas More’s Utopia. It discusses three different ways to describe the meaning-making contexts that the authors of these textbooks create. Firstly, diachronic lines are formulated both forwards and backwards. Secondly, the textbook authors formulate synchronous contexts that focus on the historical conditions that prevailed when Utopia was written. Thirdly, the chapter brings light on an “occidental narrative” of progress, based on nineteenth and twentieth century historiography that the textbooks use for contextualization. In addition, the chapter draws attention to how the contexts in the textbooks are more often implicit constructs rather than explicitly developed tools of analysis. The aim of the chapter is to indicate how a discussion about these ways of contextualizing historical material can contribute to making visible how certain notions of context always influence history writing. As historians, we have everything to gain from actively describing and discussing how we produce and use different historical contexts to understand, explain and bring order to the multifaceted polyphony of the past.
Kontexter som tidsskikt
Authors: Fareld Victoria
Published: April 2022

A core assumption in the fields of historical studies is that historical understanding requires contextualization. If we want to understand something historically, we have to consider this something in context. This chapter challenges an idea of historicization as tantamount to situating texts in already-defined contexts and argues for a contextualizing practice that can account for several ongoing pasts in the present. It proposes an understanding of contexts as time layers which would direct our attention to the multi-temporality of historical texts, rather than to their specific location within an already chronologically determined past. It is argued that such an understanding would enrich our contextual work by making visible the histories of the many times present in the texts and phenomena we study.
Historisera nutiden! Att skapa stora diakrona meningssammanhang för nutidens praktiska frågor
Authors: Wiklund Martin
Published: April 2022

Whereas historical contextualization is often understood in terms of reconstructing conditions and circumstances in the past, this chapter analyses how to historicize the present. More specifically, it investigates how to construct large diachronic contexts of meaning for practical questions in the present. Philippe Ariès’ history of how attitudes toward death have changed from the Middle Ages to the present in Western culture is used as a guiding example. Compared to many other historians of mentalities who also use large diachronic perspectives, a particular feature of Ariès’ perspective is that the present is included in the diachronic context of meaning and that the diachronic context is used to historicize the present and to throw critical light on normative issues, such as how to handle death and dying. The structure of Ariès’ diachronic context of meaning is analyzed in three parts: a) a main theme that connects the past to the present (attitudes toward death), b) a differentiation of aspects of the main theme (e.g. whether death is preferably well prepared or unexpected, and whether dying is public or private), c) a periodization of the changes of attitudes that exposes contrasts and transformations that in Ariès’ view have resulted in the tendency to avoid talking about people’s own death in the twentieth century. This form of contextualization can be used also for other topics. The analysis provides guidance for historians who wish to historicize phenomena in the present by constructing a large diachronic context of meaning.
Automatic control system for walking dragline excavator digging
Authors: Pevzner L. D. , Kiselev N. A.
Published: April 2022

This paper presents the results of the development of automatic control systems for walking dragline excavator digging process. The process enables operational productivity to be enhanced through optimizing digging process. This also prevents extreme loads on machinery and hoist cable deﬂection. The paper also describes mathematical models of the electric drives of the main excavator machinery which form the bucket motion and the model of cable length change. Further the study will analyse the tructure of the control system and the automatic digging algorithm. Computer modeling ﬁndings are also described to conﬁrm the operability of the automatic digging algorithm. Computer simulation of the processes in electric drives of main machinery of a walking dragline in digging operations was performed by means of SimInTech software. The automatic control system optimizes digging trajectory with very fast penetration with permissible overregulation following digging at a constant cut depth. The integrated system of dragline operation process control is practically independent due to the following factors: the automatic digging control system in combination with automatic systems for transporting the loaded bucket to dump and the empty bucket to the face; the automatic main machinery overload protection systems; and the system of control over safe bucket movement in the dragline working space.
Моделирование феррорезонансных режимов в нелинейных электрических цепях с учетом магнитного гистерезиса
Authors: Подберезная И.Б. , Ткачев А.Н.
Published: April 2022

Приведено решение задачи численного моделирования феррорезонансных режимов напряжений и токов в электрических цепях, возникающих при последовательном и параллельном соединении нелинейного индуктивного и емкостного элементов. Вебер-амперная характеристика индуктивного элемента задана с учетом гистерезиса. Известно, что феррорезонансные режимы возникают в электрических цепях, содержащих емкостные и нелинейные индуктивные элементы, в том числе силовые трансформаторы, дугогосящие реакторы, измерительные трансформаторы тока и напряжения, электродвигатели. Нелинейность характеристик индуктивных элементов служит причиной того, что при насыщении их магнитных систем происходит изменение дифференциальных индуктивностей, в результате возникают феррорезонансные, часто нештатные и даже аварийные режимы. Для имитационного моделирования магнитного гистерезиса использована модифицированная обратная модель Джайлса-Атертона. Численное интегрирование дифференциальных уравнений, описывающих динамические процессы в электрических цепях, выполнено явным методом Эйлера. Показано, что в результате феррорезонанса возникает тригеррный эффект, проявляющийся в форме скачкообразного изменения состояния цепи, вызванного неоднозначным характером вольт-амперной характеристики для входного напряжения и тока. Предложенный метод моделирования переходных и установившихся режимов в нелинейных электрических цепях с учетом магнитного гистерезиса может быть обобщен на случай произвольных цепей, в том числе, со сложной топологией.
[RETRACTED] BioDerme Skin Serum Reviews - Where To Buy It? v1
Authors: not provided biodermeskinrumreviews
Published: April 2022

[RETRACTED]

BioDerme Skin Serum Reviews - Where To Buy It?
S1 File The Protocols for preparing the laboratory practical lessons v1
Authors: Gasparello Jessica , Zurlo Matteo , Carmela Cosenza Lucia , Breveglieri Giulia , Zuccato Cristina , Gambari Roberto , Finotti Alessia
Published: April 2022

The protocols here described are related to the sections presented in Figure 1A (open boxes) focusing on the activity performed in preparing the biological material to be used by the students during the practical laboratory lessons. All the steps are presented and critically commented when deemed useful. The reagents used during the preparation of these protocols are indicated as an example, as all the reagents can be purchased from any company.
S2 File The Protocols of the laboratory practical lessons v1
Authors: Gasparello Jessica , Papi Chiara , Zurlo Matteo , Carmela Cosenza Lucia , Breveglieri Giulia , Zuccato Cristina , Gambari Roberto , Finotti Alessia
Published: April 2022

The protocols here described are related to the sections presented in Figure 1B focusing on the practical activity performed by the students. All the steps are presented and critically commented when deemed useful. The reagents used during the preparation of these protocols are indicated as just an example, as all the reagents can be purchased from any company.
Reconstruction of radio images from a multifrequency multistatic radio hologram using the nonequidistant FFT method
Authors:   Bauman Moscow State Technical University, Krainy Vladimir I. , Semenov Aleksandr N. ,   Bauman Moscow State Technical University, Sergeeva Anastasiya A. ,   Bauman Moscow State Technical University
Published: April 2022

The article considers the transformation of the back-projection method (focusing) for recovering geometry from the knowledge of the scattered field received with a multi-static radar system (multi-static radio hologram). It is shown that it can be expressed as a two-dimensional non-equidistant Discrete Fourier Transform (NDFT). An example of focusing a multi-frequency multi-static radio hologram of a flat multipoint object is given, and a reconstructed image is obtained based on the back-projection algorithm and the NDFT algorithms. A modification of NDFT based on the fast Gaussian gridding of non-uniform nodes (NuFFT), implemented in MATLAB, is used to speed up image reconstruction. A numerical experiment indicates similar reconstructed images obtained by the backpropagation method and with the two-dimensional NuFFT method. However, the NuFFT method was 740 times faster. The results show a significant reduction.
Anatoly V. Kozar (to 75th anniversary of birth)
Authors:   Editorial Board of RENSIT Journal, Grachev Vladimir I.
Published: April 2022

Information about Anatoly Viktorovich Kozar - Doctor of Physical and Mathematical Sciences, Professor of the Department of Photonics and Microwave Physics of the Faculty of Physics of Lomonosov Moscow State University is presented, a full member of the Russian Academy of Natural Sciences, a well-known specialist in the field of radiophysics, optics and condensed matter physics: basic biographical data, education at the Faculty of Physics of Lomonosov Moscow State University, work at the Faculty of Physics of MSU, defense of candidate and doctoral (Physical and Mathematical Sciences) dissertations, authorship of more than 150 scientific papers in scientific journals, membership in academic councils, participation and organization of Russian and international conferences and seminars, editing in scientific journals, guidance of graduate students , doctoral and candidate dissertations.
Limitation of the Principle of Publicity in Child Adoption Cases
Authors: Shemeneva Olga N.
Published: April 2022

The article analyzes the advisability of limiting the principle of publicity in the consideration of civil cases regarding child adoption. The substantial reasons for this are as follows. First, the need to protect the interests of the adoptive parents who make the difficult decision to accept a child into the family in the hope that the child will consider them as his parents through which they can build a communication with him and his upbringing. Second, the need to protect the interests of children whose full upbringing and development are possible if they are convinced that they are growing up in their home family. Third, the need to protect the interests of biological parents who may not wish to publicize that they were forced to transfer their children for adoption and many other reasons. Meanwhile, the interest of society to access information about this category is also noted by scientists specializing in various fields of knowledge, lawyers, sociologists teachers, psychologists, and potential adoptive parents who wish to further understand what child adoption entails in their future and the experience of recognized members of society regarding child adoption. Thus, a procedural rule guaranteeing the secrecy of child adoption is formulated as follows: the court is obliged to hold a closed court hearing if there is an application for this by the adoptive parents.
The role of the geriatic (G8) health status screening tool in prediction of antitumor therapy complications in elderly patients
Authors: Yugay S. V. , Krasavina M. A. , Tyutrina Yu. A. , Nikitina T. P. , Elmurzaev A. B. , Rykov I. V.
Published: April 2022

Introduction: The G8 Score is an important tool for geriatric assessment in current oncology practice. The G8 Score is applied as a prescreening method for selection of patients who need comprehensive geriatric assessment (CGA); however, this questionnaire has not been validated in Russia.

Study goal: To evaluate the reliability and predictive role of the Russian version of the G8 Score in evaluating the risk of complications of systemic antitumor therapy in elderly patients.

Materials and methods: The authors conducted a prospective non‑randomized study in elderly patients (≥ 65 years old) who received systemic antitumor therapy. All patients were screened using the Russian version of the G8 Score. Cases of adverse events during treatment (toxicity) and treatment discontinuation were analyzed. The area under the ROC curve (AUC) was used to evaluate the specificity and sensitivity of the Russian version of the G8 Score as a predictor of complications and complication‑associated events (treatment discontinuation) in cancer patients in Russia. The reliability of the Russian version of the G8 Score was also assessed using Cronbach»s alpha coefficient of internal consistency.

Results: The data of 133 cancer patients (57,1 % and 42,9 % of whom were female and male, respectively) with a mean age of 72,1 y. o. were analyzed using the Russian version of the G8 Score. The study demonstrated a satisfactory predictive ability of the tool in terms of prognosis of general toxicity, including hematologic and non‑hematologic toxicity, with the area under the curve (AUC) being 0,621 [95 % CI: 0,524–0,717]. The cut‑off value of the G8 Score was 13,5; sensitivity (Se) = 71 %, specificity (Sp) = 54 %. The characteristics of the positive and negative predictive values of the G8 Score were similar. The data on the predictive role of the Russian version of the G8 Score in terms of prognosis of toxicity‑related treatment discontinuation were not statistically significant (p > 0,05). The internal consistency of the Russian version of the G8 Score was demonstrated to be acceptable, with Cronbach»s alpha coefficient of 0,709 and split‑half values of α1 = 0,558 and α2 = 0,432. The results of the study indicated a satisfactory reliability of the Russian version of the G8 Score.

Conclusion: The Russian version of the G8 Score is a reliable tool that can be used as a possible predictor of toxicity of antitumor drug therapy and a useful tool for the selection of patients for comprehensive geriatric assessment.
Elevated levels of CA125 (MUC16) in metastatic gastric cancer as a strong predictor of poor survival
Authors: Semenov N. N. , Dalgatov K. D.
Published: April 2022

Introduction: CA125 is an extracellular domain of MUC16 glycoprotein. The clinical significance of serum CA125 has been most extensively studied in ovarian cancer. The significance of serum CA125 in gastric cancer has not been fully elucidated. There is evidence that MUC16 overexpression is associated with poor survival in patients with metastatic gastric cancer. We have not found any research papers on the correlation between the levels of serum CA125 and MUC16 overexpression.

Objective: The objective of the study was to assess the effects of elevated CA125 levels in patients with metastatic cancer on the long‑term results (time to disease progression and overall survival).

Materials and methods: CA125 was determined in the serum before the start of first‑line chemotherapy in 75 patients (45 males and 30 females) with metastatic gastric cancer. The mean age of the patients was 61,3 (26,7–84,9) years. Synchronous metastases were observed in 85 % of patients: 57,3 % in the peritoneum, 37,3 % in the liver, 5,4 % at other sites. Palliative gastrectomy and metastasectomy were performed in 28 % and 20 % of patients, respectively. Monotherapy, doublet and triplet chemotherapy regimens were used in 6,7 %, 58,7 % and 36,0 % of patients, respectively.

Results: the analysis showed that elevated levels of CA125 (> 37 IU/mL) were associated with a significant reduction in median time to progression (3,5 months (CI 2,87–9,53) vs 6,2 months, р = 0.001 (CI 2,02–4,9)) and overall survival (5,1 months (CI 6,07–28,1) vs 17,1 months (CI 3,5–6,67), р = 0.001). One‑factor ANOVA showed that factors with the strongest effects on the survival rates included the location of metastases (peritoneum), tumor histology (adenocarcinoma/signet ring cell carcinoma), the use of palliative gastrectomy and metastasis resection. A multi‑factor ANOVA showed that the only favorable prognostic factors in terms of overall survival rates were normal CA125 levels (HR 0,39 (95 % CI 0,18–0,84), р = 0.001) and the use of palliative gastrectomy (HR 0,23 (95 % CI 0,1–0,58), р = 0.001). The use of triplet chemotherapy regimens allowed to slightly improve the overall survival rates in the group of patients with elevated CA125 levels; however, the differences were not statistically significant (6,7 months vs 4Ю0 months, p = 0.29).

Conclusion: Elevated levels of CA125, which reflect MUC16 overexpression to a certain extent, is a strong independent predictor of poor outcome in metastatic gastric cancer. Currently, a possible way to overcome this negative impact is to use more intensive chemotherapy regimens. However, further research should be aimed at finding adequate targets and ways of neutralizing the negative impact of MUC16 overexpression in patients with metastatic gastric cancer.
ARTICULAÇÕES DO TURISMO DE VERANEIO NAS CIDADES DO SALGADO (PA)
Authors:   Universidade do Vale do Paraíba - Univap, Santos Karina Pimentel dos , Costa Sandra Maria Fonseca da ,   Universidade do Vale do Paraíba - Univap
Published: April 2022

O presente trabalho tem como objetivo analisar a dinâmica do turismo de veraneio nas pequenas cidades na microrregião do Salgado (PA) e seus reflexos na dinâmica socioespacial. O turismo em busca das praias e do lazer proporcionam dinamismo para os centros urbanos e fortes interações espaciais com outras cidades, pelo fato de serem cidades estratégicas para o lazer aos finais de semana, feriado e meses de férias, pelo privilégio natural e paisagístico, possuindo belíssimas praias, rios, igarapés e balneários, por isso sua classificação de turismo de veraneio. Para alcançar esses resultados, a metodologia da pesquisa foi baseada em três etapas: a primeira foi a revisão da literatura (histórica e conceitual); a segunda etapa foi a coleta de dados secundários; e a terceira etapa composta pelo trabalho de campo nas cidades de Marapanim e Salinópolis, os centros de destaque na dinâmica da região do Salgado.
Factors and outcome analysis of emergency peripartum hysterectomy in a tertiary care center catering to hilly terrain for a five-year period: a retrospective study
Authors: Makhija Amrita , Pati Banishree , Upreti Purnima
Published: April 2022

Background: Emergency peripartum hysterectomy (EPH) is a life-saving surgery associated with significant morbidity and mortality. In the state of Uttarakhand, due to the hilly terrain and poor ante-natal awareness, type 1 and 2 delay is expected in seeking health care. Thus, the present study was conducted in a tertiary care hospital to evaluate the incidence, risk factors, indications, and outcomes of EPH.Methods: Medical records of 63 patients who underwent EPH from January 2015 to December 2019 were retrospectively analyzed for the patient characteristics, high risk factors, indications and type of hysterectomy and outcome.Results: The incidence of EPH at our institute was 2.78 per 1000 deliveries. Most patients (89.89%) were referred cases. There were 4 home deliveries and 4 patients referred for obstructed labour.  The average parity was 2.71±1.13. Thirty-four patients (53.97%) presented in the emergency department in shock. The leading indication was uterine atony (46.03%) followed by rupture uterus (26.98%) and placenta accreta spectrum (23.81%). All patients needed blood transfusion. Intensive care unit admission was required in 88.89%. The maternal mortality was 15.87%.  All the three levels delays contributing to poor outcome were identified. Conclusions: Uterine atony and rupture of non-scarred uterus due to obstructed labour were the prominent indications of EPH. Strengthening of referral system and timely referral of high-risk patients to a setup with facilities for management of high risk obstetric cases can play an important role in decreasing the incidence and morbidity and mortality of EPH.
Hablando de integridad en agua y saneamiento: evolución reciente del debate sobre integridad y transparencia en el sector de agua y saneamiento en América Latina y el Caribe
Authors: Ortiz Raphaëlle , Núñez Anamaría , Basani Marcello , Gamba Jacopo , Calderón Claudia , Núñez Patricia
Published: April 2022

Las conversaciones digitales públicas ayudan a entender la manera en que el público, los gobiernos y las empresas proveedoras de servicios mencionan y perciben tópicos importantes como la integridad y la transparencia en el sector de agua y saneamiento. Este informe analiza medios sociales digitales disponibles públicamente, incluyendo artículos de noticias, blogs y tweets, para identificar contenido referido a la integridad y transparencia del agua y saneamiento en América Latina y el Caribe entre enero de 2016 y julio de 2020. El siguiente análisis busca descubrir tendencias, móviles y distribución de estas conversaciones. También se analizan las diferencias entre fuentes (por ejemplo: canales digitales de noticias versus redes sociales) y el impacto que tuvo la pandemia de COVID-19 sobre los tópicos y volumen del debate.
Methods of Putting Forward Alternative Historical Hypotheses in Science and Beyond: Philosophical and Methodological Analysis
Authors: Nekhamkin Valeriy
Published: April 2022

The article deals with the counter-factual modeling of the past. One of the methodological directions of improving this approach is being studied. The methods of putting forward alternative historical hypotheses are revealed. It is stated that hypotheses should be distinguished within the framework of Alternate History. For this purpose, a level approach is taken from the philosophy. The following levels of Alternate History are distinguished: personalistic, event-based, and factor-based. It is shown that each level has a certain set of methods for proposing alternative hypotheses. The features of the application of these means of cognition in the framework of counter-factual modeling of the past are fixed.
Hansa Silver Export In the First Half of the 16th Century and It’s Role in the Fate of the Novgorod German Yard
Authors: Bessudnova Marina
Published: April 2022

Silver coming through the Hanseatic trade routes to Livonia and further to Russia, was a constructively significant element of the Russian-Hanseatic system of exchange of goods. As a merchandise — “currency”, it replenished the volume of Hanseatic goods entering the Russian market, insufficient for trading on the barter basis, and provided loans and advance payments for trade transactions in the context of the development of trade cooperation. The restoration of the Hanseatic office in Novgorod (German yard) in 1514 was used by Revel in order to establish its own control over the supply of silver to Novgorod and for the transformation of the German yard into a kind of depository or “money place” (Geldstelle), the existence of which was provided for by the order of Hanseatic trade if credit transactions have taken place. This German yard function explains Hanseatic perseverance in the preservation of their Novgorod office.Revel's strategy was aimed to gain leadership in Russian trade and therefore assumed the suspension of Danzig, closely tied with the Fuggers, from the supply of silver to Russia, blocking the Riga- Dorpat-Pskov channel, as well as the management of the company for the unification of its purity standards and the establishment of standard labeling, which facilitated the use of silver as a merchandise — “currency”. Since the beginning of the 1520s, silver inflow to Novgorod has significantly decreased due to the monetary reform carried out by the Livonian Landsgerrs and the introduction of the restrictions (since 1537 — prohibition) on the export of silver from Livonia.The consequence was the destruction of the traditional order of trade between Novgorod and Hansa through mediation by the Livonian cities, led by Revel who controlled the German yard, and creation of a new system based on Lubeck.
Japan vs the United States (1941—1945). People and Machines
Authors: Popov Grigorij
Published: April 2022

The authors study the military potential of the Japanese Empire and its changes during the Pacific War in order to understand the role of the Pacific Theater of Operations in World War II. In this regard, the authors basing on the losses suffered by Japan on various fronts define the role of the USSR in the defeat of militaristic Japan. They argue that the contribution of the USSR to the victory of the Anti-Hitler coalition in Asia consists mainly in shackling significant forces of the Japanese army in Manchuria and Korea until the end of the summer of 1945, which did not allow the Japanese military to win to a large extent in the southwestern provinces of China, thereby ensuring direct communication with Burma. As for the defeat of the Japanese Air Force, which was the main striking force of Japanese militarism, there was a decisive contribution of the United States, whose Air Force also caused significant damage to Japanese industry by the summer of 1945 with strategic bombing. In this regard, the authors question the need for atomic bombing, which accelerated the surrender of Japan, but did not make it, as the authors prove, inevitable. The authors see the main reason for Japan's defeat in the strategy of its High command, putting the economy in second place. The Japanese admirals exaggerated the capabilities of carrier-based aircraft too much, which became a fatal factor for Japan in the Pacific war. The authors also claim that the actions of the Allied troops in Burma played a significant role in the defeat of Japan.
Features of the Development of Online Scientific Periodicals on the Example of the Journal “ISTORIYA”
Authors: Yablokov Boris
Published: April 2022

This review focuses on the history of the electronic scientific and educational journal “ISTORIYA”, stages of its formation and the factors influencing its development. The emergence of online journals, distinguished by the dynamic nature of filling the editorial portfolio providing a much higher level of scientific communication compared to traditional print publications, was a reflection of the rapid introduction of Internet technologies into the daily practice of the humanities. This led to a search for informational and technological solutions that would automate the ways of communicating and processing scientific periodicals against the background of the growth of publication activity and the widespread use of scientometrics. One of such solutions was the creation of publishing platforms, a striking representative of which was JES (Journal of Education and Science) developed in Russia in 2013, which subsequently provided automation of the editorial-publishing cycle for a number of socio-humanitarian journals. The Journal “ISTORIYA”, which at the time served as a guide to technological solutions that took into account the most current trends in the development of forms of scholarly communication, was a flagship publication of the platform. Due to this advantage? the Journal “ISTORIYA”, created by the efforts of the State Academic University for the Humanities and the Institute of World History of the Russian Academy of Sciences, has managed not only to take its rightful place among the leading scientific periodicals in a relatively short period of time, but also to acquire a reputation as a media of the highest quality, becoming a “business card” of successful integration of science, education and modern information technology.
“Translations in the History of the Middle Ages and in the Work of the Medievalist”: Conference of the Journal “Srednie Veka”
Authors: Mastyayeva Irina
Published: April 2022

The article describes in detail the conference “Translations in the History of the Middle Ages and in the Work of the Medievalist” of the journal “Srednie veka. Studies on Medieval an Early Modern History”, which took place in September 2021. You can find in the review the statistics of the conference (number of papers, general information about the participants), topics of the sections, the problems, concerning in the papers. The conference was devoted to one of the most important topics for specialists in the history of Middle Ages — translation. The author of the article divided the presentations of the speakers into three groups, based on viewpoint on the problem of translations was chosen by the researcher: translation and translators in the Middle Ages, “translation technique” in the work of medievalists, the role and place of translations of medieval texts in historical studies and beyond.
Soviets of Workers' and Soldiers' Deputies and Zemstvo Soviets in the Baltic Provinces in 1917: the Formation of National Statehood and Proletarian Internationalism
Authors: Bahturina Alexandra
Published: April 2022

The article examines the interaction and conflicts between the Zemstvo Councils and the Councils of Workers' and Soldiers' Deputies on the issues of the future organization of power in the territories of the Estland, Livonia and Courland provinces. It is shown that representatives of the liberal public of Estonia and Latvia in the spring of 1917, with the help of the Provisional Government, managed to create Zemstvo Councils and abolish the authorities of the German noble self-government, provoking protests from the Soviets of Workers' and Soldiers' Deputies, who regarded this as the removal of workers from power. The article analyzes the attitude of the Soviets of Workers' and Soldiers' Deputies to the slogans of national autonomy and national statehood, which were in contradiction with the ideas of proletarian internationalism. In practice, the Soviets sought to organize power separately on the territory of Estonia and Latvia, outside the all-Russian associations of Soviets, thus providing, along with the Zemstvo Councils, conditions for the creation of national statehood. It is concluded that organizations of different political orientation — Zemstvo Councils and Councils of Workers' and Soldiers' Deputies — contributed to the creation of national statehood in Estonia and Latvia by their activities in 1917.
Behaviour Strategies of the Foreign Diplomats at the Perpetual Diet of the Holy Roman Empire in the 18th Century
Authors: Petrova Maria
Published: April 2022

The article analyses the changes that took place in the official diplomatic communication of European rulers after the Thirty Years' War and the conclusion of the Peace of Westphalia in 1648, which affirmed a number of sovereign rights to the Estates of the Holy Roman Empire of the German nation (and former vassals of the emperor), including the right to send and receive ambassadors. The new sovereigns, primarily the princes-electors, began to fight for the so-called royal honours (honores regii), which were de facto expressed in a certain set of ceremonies in relation to the ambassadors of the crowned heads and republics assimilated to them. The arena of the struggle for the royal honours was the Imperial Diet of the Holy Roman Empire in Regensburg — a general assembly of all Imperial Estates (in the middle of the eighteenth century — their representatives), by which since the end of the 17th century foreign diplomats had been accredited (first France, a little later — Great Britain, the United Provinces of the Netherlands, in the middle of the eighteenth century — Russia). Having declared their representatives in 1702 as the ministers of the first rank, the electors tried for a century to force the “old” monarchs to send ambassadors to the Diet, and they, by custom, were sent only to the sovereigns. Comparing the various ways out of the ceremonial impasse, the author comes to the conclusion that the struggle for elusive precedence, which foreign diplomats of the second rank (envoys or ministers plenipotentiary) waged with the representatives of the electors at the Imperial Diet, was a deliberately unwinnable strategy, leading either to their isolation or to the recall from their posts. A much more effective strategy that did not damage state prestige was to send to Regensburg so-called ministers without character or residents, who occupied a less honorable position in comparison with ambassadors and envoys, but according to their status were freed from the opportunity to compete with them and, as a result, to come into conflict.