bluuebunny/crossref_metadata_2025 huggingface dataset:
Polyfunctional Biopreparations-Crude Oil Destructors: The Effect on Plants and the Content of Oil in the Soil
Authors: Korshunova T.Yu. , Bakaeva M.D. , Loginov O.N.
Published: October 2018

The results of an experiment on cleaning oil-contaminated soil and accelerating the restoration of its fertility with the aid of combined biopreparations containing bacteria that degrade oil and microorganisms that can stimulate the growth and development of plants. It is shown that the introduction of bacterial mixtures reduced the oil content by 3.1–3.6 times and increased by 2-3 orders the number of basic physiological groups of soil microorganisms participating in its transformation, and also accelerated the germination of seeds (for 2 days) and the beginning (for 6–7 days) of all stages of oat development, used as a phytomeliorant. The most effective was a biopreparation consisting of a consortium of microorganisms Acinetobacter calcoaceticus IB DT-5.1/ 1 and Ochrobactrum intermedium IB DT-5.3/2 and strains of Pseudomonas koreensis IB-4 and Paenibacillus ehimensis IB 739, which, among other things, increased the mass of oat shoots in 2.3–2.6 times and their length is 54.0–77.8% compared to plants in the soil untreated with bacteria with oil.
Management of Environmental Activities in the Development of Open-Cast Iron Ore Deposits on the Territory of Kuznetsk Alatau in Khakassia
Authors: Zen’kov I.V. , Ganieva I.A. , Androkhanov V.A. , Anikina Yu.A. , Kazanskaya N.N. , Safronov M.V. , Sycheva E.M.
Published: October 2018

Based on the results of processing satellite images with the delineation of boundaries and classes of mining industrial landscapes in the area of spent quarries and rock dumps, the self-healing coefficients of the vegetation cover in the range of 0.035–0.12 are determined. For all objects of the mining landscape with low values of self-regeneration coefficients of ecosystems, a set of special works on mining and biological reclamation of disturbed lands was recommended. It is established that in the conditions of the mountainous area of the Kuznetsk Ala-Tau, the processes of self-healing of the plant ecosystem are characterized by low rates of their flow in time and are ineffective from the viewpoint of restoring the ecological balance.
Results of Remote Monitoring of Ecology of Disturbed Lands by Iron Ore Quarries of Irkutsk Oblast
Authors: Zen’kov I.V. , Izhmulkina E.A. , Androkhanov V.A. , Vokin V.N. , Anischenko Yu.A. , Agalakova A.V. , Latyshenko G.I.
Published: October 2018

Based on the results of processing satellite images with the delineation of boundaries and grades of mining industrial landscapes, environmentally acceptable selfhealing factors for vegetation cover at the level of 0.791 are established in the territory of railway dumps. The lower values of such coefficients in the range 0.049–0.48 are characterized by self-healing of the vegetation cover on the surface of automobile dumps.
Online Alışverişte Bilişsel Çelişki Davranışlarının İncelenmesi
Authors: AYDIN Hatice , YILMAZ Özer
Published: October 2018

Bilişsel
çelişki, tüketicinin satın alma davranışı ile ilgili yaşadığı kaygı ya da
belirsizlik durumunu ifade etmektedir. Bu belirsizlik, geleneksel alışveriş
alışkanlıklarıyla büyüyen Y kuşağı üzerinde daha da yüksek olabilmektedir. Bu
çalışmada hedonik tüketim eğilimi, içgüdüsel alım, algılanan risk, değer ve
güven faktörlerinin bilişsel çelişkiye ve bilişsel çelişkinin yeniden satın
alma niyetine etkisini tespit etmek amaçlanmıştır. Bu amaçla internetten
alışveriş yapan tüketicilere online anket yöntemi uygulanmıştır. Araştırma
modelinin verileri kolayda örnekleme yöntemiyle elde edilmiş ve Kısmi En Küçük
Kısmi Kareler (PLS) yöntemine dayanan yapısal eşitlik modellemesi ile analiz
edilmiştir. Araştırmadan elde edilen sonuçlara göre, hedonik tüketimi eğilimi,
içgüdüsel alımlar, algılanan risk ve algılanan değer bilişsel çelişki üzerinde
etkilidir. Ayrıca bilişsel çelişki yeniden satın alma niyetine etki etmektedir.
Çalışmanın sonuçları itibari ile literatüre ve gelecek çalışmalara yol
gösterici olması beklenmektedir.
Turismo fluvial: una alternativa para fomentar la actividad turística en los municipios ribereños al río Magdalena. El caso del municipio de Suárez (Tolima, Colombia)
Authors: Galvis Rivera Nicolás
Published: October 2018

Debido a su enorme aporte social, cultural y turístico, en las últimas décadas, los ríos han adquirido mayor relevancia en el sector. Esto se evidencia, especialmente, en las zonas rurales, gracias a que su belleza natural es única y se entreteje con el paisaje cultural y la cotidianidad de los ribereños. El objetivo de la investigación fue conocer los contextos y las potencialidades que ofrece el río Magdalena en el municipio de Suárez (Tolima) en lo que concierne al impulso del turismo fluvial en la región del Alto Magdalena, departamento del Tolima. Para el levantamiento de la información se emplearon cuatro técnicas: observación de campo, entrevista y comunicación oral, encuesta y técnicas de grupo. Adicionalmente, se realizó una caracterización de los atractivos turísticos y una evaluación de las variables que integran el producto turístico, para determinar si Suárez es un destino potencial, emergente o consolidado.

El hilo conductor de la investigación fue la planificación territorial del turismo, junto con el enfoque teórico de la valorización turística, en el que se analiza el turismo como un fenómeno social complejo y como medio para brindar oportunidades de trabajo y calidad de vida a los pobladores que habitan la ribera del río Magdalena.
Lineamientos estratégicos para la gestión del turismo en el Distrito de Buenaventura (Colombia)
Authors: Arboleda Montaño Nixon
Published: October 2018

El presente trabajo de investigación propone lineamientos estratégicos para la gestión del turismo en el Distrito de Buenaventura. Para lo anterior, se parte de la realización de un diagnóstico, el cual incluye un análisis de las dimensiones ambiental, social, económica y político-institucional. También se realizan cuatro análisis: de la situación turística, de la oferta turística, de la demanda y uno dofa, en el que se destacan las principales debilidades, oportunidades, fortalezas y amenazas del turismo en Buenaventura. Con respecto al inventario de atractivos turísticos, se resaltan los principales atractivos turísticos naturales y culturales que tiene el Distrito, con su debida descripción y definición de importancia evidenciada en la clasificación y el nivel de jerarquía que se le otorga a cada atractivo de acuerdo con las metodologías cicatur/oea y del Ministerio de Comercio, Industria y Turismo (2010). Finalmente, se establecen las áreas de acción, las estrategias, las acciones, los responsables y el tiempo que permitirán materializar los lineamientos estratégicos para la gestión del turismo en Buenaventura. Se espera que su implementación conduzca a mejorar la actual situación que el Distrito de Buenaventura tiene en esta materia.
Racionalidad crítica y conocimiento del turismo
Authors: Muñoz de Escalona Francisco
Published: October 2018

Aunque haya quien lo ignore, incluso quienes lo obvien, lo que llamamos realidad no deja de ser un mero constructo teórico. Los hombres –y también las mujeres, claro– consiguieron nombrar pronto lo que con sus cinco sentidos perciben. Por eso, el Génesis acierta al afirmar que al principio fue el Verbo, quiso decir, la palabra. Acertó de plano el vetusto profeta. Gracias a su enseñanza sabemos lo que vemos, tocamos, olemos, gustamos y oímos. Pero la humanidad no quedó estancada en sus primeras nominaciones. Al ritmo de su lenta evolución, y de sus crecientes necesidades, las sometió a una crítica tenaz. De ella proceden el avance del conocimiento, en general, y el científico, en particular. La realidad a la que llamamos turismo no queda al margen de este proceder. Por ello, hoy disponemos de planteamientos críticos que han dado luz a interpretaciones (teorías) sometidas, como todas, al proceso de proposición, selección y eliminación de error, para volver a iniciar el proceso en un ciclo sin fin.
Nuevos retos en el tercer país: migraciones y gestiones administrativas de la frontera colombo-venezolana
Authors: Polo Alvis Sebastián , Serrano López Enrique , Triana Barragán Francelly Steffany
Published: October 2018

A partir de una revisión de la actualidad de la realidad migratoria entre Colombia y Venezuela, este artículo pretende realizar un análisis sobre los diversos avances adminis­trativos de la gestión fronteriza. A pesar de la gran importancia que han suscitado las mi­graciones venezolanas en Colombia a lo largo de los últimos cinco años, la comprensión de los elementos políticos, económicos y sociales de las condiciones internas de ambos países pueden dar luces de las lógicas correctas para la adecuada gestión administrativa de la fron­tera. Se espera que el lector, además de tener una visión sobre el estado de las migraciones bilaterales entre Colombia y Venezuela, pue­da tener una perspectiva más profunda sobre los retos a la gobernabilidad de la frontera colombo-venezolana.
Dimensiones locales de la seguridad y la cooperación transfronteriza en la frontera amazónica de Brasil, Colombia y Perú
Authors: García Pinzón Viviana
Published: October 2018

Tanto en la visión tradicional de la se­guridad como en la perspectiva que enfatiza el papel de las nuevas amenazas, las fronteras ocupan un rol central. Sin embargo, la litera­tura reciente sobre fronteras ha resaltado las limitaciones para el entendimiento y el estudio de la seguridad y defensa en estos territorios, los cuales siguen siendo poco comprendidos. Por ello, se ha resaltado la necesidad de analizar estos temas teniendo en cuenta las particulari­dades de dichas áreas. Sin embargo, el proble­ma no se restringe a lo teórico, por el contrario, el proceso de política pública sobre seguridad y cooperación fronteriza en Colombia ha estado controlado por las visiones y los intereses de actores nacionales, siguiendo una dinámica de “arriba hacia abajo” (top-down) que deja poco espacio para la participación de los actores lo­cales. Esto constituye un obstáculo para la te­rritorialización de la intervención pública y su efectividad. Con base en estas consideraciones, el objetivo central de este artículo es describir y analizar las visiones sobre seguridad, coope­ración y relaciones transfronterizas por parte de actores locales en el lado colombiano de la triple frontera amazónica (Brasil-Colombia- Perú). Además de visibilizar las perspectivas de dichos actores, este ejercicio permite evidenciar las debilidades y los desafíos de la política pú­blica de seguridad en áreas de frontera.
Una aproximación geopolítica a la política binacional de seguridad fronteriza entre Colombia y Panamá
Authors: Niño González César Augusto , Jaramillo Ruiz Felipe
Published: October 2018

La tradición geopolítica entre Colombia y Panamá se distancia de las aproximaciones clásicas a las relaciones internacionales. Las ca­racterísticas geográficas de la región fronteriza brindan la posibilidad de ampliar el prisma teórico para analizar la manera como se regula el espacio limítrofe entre los Estados. A par­tir del caso de estudio Colombia-Panamá, el artículo evidencia los límites conceptuales de las principales aproximaciones geopolíticas. Así, propone desarrollar una agenda investi­gativa que se aleje de los presupuestos Estado-céntricos, conflictivos y expansivos que suelen dominar el estudio de la regulación territorial en las relaciones internacionales.
Estrategia de internacionalización del Ejército de Liberación Nacional (ELN) y seguridad fronteriza
Authors: Luna Beltrán María Camila
Published: October 2018

¿Cuál es el alcance que puede llegar a tener una estrategia de internacionalización diseña­da, no desde un Estado, sino desde un grupo subversivo como el eln? Para responder a esta pregunta se revisaron conceptos referentes a la internacionalización, y se analizaron las lí­neas del eln sobre esta, ancladas en su origen e inicios; la estrategia de internacionalización en medio de las negociaciones de paz, y la regionalización por el repliegue del eln hacia zonas fronterizas. Además, se estudió el impac­to de esta estrategia en la dinámica general del conflicto colombiano y la seguridad fronteriza. Finalmente, se evalúa la correlación de fuerzas e incentivos para la actual negociación de paz Gobierno-eln.
Conversor Boost Quadrático-buck utilizado no Acionamento de um vetor de Led Empregado no Tratamento de Disfunções Celulares
Authors: Silva Welker Gomes , Rodovalho Diógenes Simão , Silva Fábio Vincenzi Romualdo da , Morais Josué Silva de , Freitas Luiz Carlos de , Coelho Ernane Antônio Alves , Júnior João Batista Vieira
Published: October 2018

Esse artigo apresenta a implementação de um conversor CC-CC Boost-Quadrático-Buck usado no acionamento de um vetor de LED empregado em Terapia Fotodinâmica. O conversor proposto opera com uma chave ativa e pode ser alimentado desde 12 VCC até 180 VCC. Esta característica permite que o conversor seja alimentado pela rede de distribuição de energia ou por bateria. Resultados experimentais extraídos de um protótipo de 80 W são apresentados.
Application of Some Artificial Intelligence Techniques in Induction Motor Fault Diagnosis
Authors: Silva Edison R. C. da , Razik Hubert , Baccarini Lane M. R. , Corrêa Maurício B. de R. , Jacobina Cursino B.
Published: October 2018

In spite of the advantages of the use of the induction motor in a large number industrial applications, various stresses natures like thermal, electrical, mechanical or environmental could affect the life span of this induction motor drive. In recent years, monitoring and fault detection of electrical machines have moved from traditional techniques to artificial intelligence techniques. This paper gives examples of application of nine AI techniques already applied to induction motor fault diagnosis: neural networks, fuzzy logic, neural-fuzzy, genetic algorithms, vector support machine, particle swarm optimization, artificial immune system and gaussian bootstrap process. Functions that can be accomplished by them are highlighted.
Investigación y ciencia: implicaciones para un docente investigador en el sistema colombiano
Authors: Mosquera Ayala Ana María
Published: October 2018

Voluminosos descubrimientos científicos se realizan con frecuencia en diferentes partes del mundo. Generalmente, la socialización de estos se desarrolla a partir de la academia y sus procesos de divulgación a la investigación, cuyos productos: artículos, libros, capítulos de libros, patentes, entre otros, representan un gran indicador de desarrollo para la ciencia, la tecnología y la innovación en cada país.
Clinical and morphological characteristics of restrictive cardiomyopathy associated with mutations in the filamin c gene
Authors: Melnik O. V. , Knyazeva A. A. , Poluboyarinova O. Y. , Vakhrushev Yu. A. , Fomisheva Yu. V. , Sitnikova M. Yu. , Simonenko M. A. , Vershinina T. L. , Kozyreva A. A. , Polyakova A. A. , Vasichkina T. S. , Gudkova A. Ya. , Kostareva А. А.
Published: October 2018

Previously, it was believed that mutations in filamin C are able to cause only skeletal myopathies, cardiac tissues have not been studied. However mutations in FLNC have been recently found that lead to both joint damage to the skeletal and cardiac musculature and to isolated cardiac tissue damage. Moreover, had known that mutations in FLNC are associated with all known types of cardiomyopathies (HCM, DCM, RCM, arrhythmogenic) аt present. The article presents our own clinical observations of an adult and children’s cases of isolated phylaminic RCM based on our institution. The study of this problem will allow us to include the known mutations in the genetic screening panels, which will lead to early diagnosis of cardiomyopathies associated with mutations in FLNC and the ability to prevent rapid disease progression and more later cardiac transplantation in the future.
New Forecasting Technique for Intermittent Demand, Based on Stochastic Simulation. An Alternative to Croston’s Method
Authors: Doszyń Mariusz
Published: October 2018

The main aim of the article is to present a new forecasting technique, applicable in case of intermittent demand. To present properties of this new technique, the accuracy of the predictions generated by the Croston’s method and by the author’s method (based on stochastic simulation) was analyzed. For comparison, methods such as moving average and simple exponential smoothing are as well used as a reference. Also the SBA method, a modification of Croston’s method, is applied. Croston’s method is an extension of adaptive methods. It separates the interval between the (non‑zero) sales and the sales level. Its purpose is to better forecast intermittent (sporadic) demand. The second prognostic method is the author’s proposal which relies on two stages. In the first stage, based on stochastic simulation, it determines if an event (sale) occurs in a given period. In the second stage, the sales level is estimated (if the previous stage shows that the sales will occur). Due to the strong asymmetry of the sales, the sales level is determined on the basis of the corresponding quantiles. The basis for forecasting are weekly sales series of about fourteen thousand products (real data). The analyzed time series can be defined as atypical, which is manifested by a small number of non‑zero observations (high number of zeros), high volatility and randomness (randomness tests indicate white noise). Forecast error measures are used to characterize both the bias and the efficiency. The forecast error measures will be characterized so that they can be applied to a time series with a large number of zeros (including the author’s forecast error measure proposal). Forecasts were evaluated with respect to the distributions of four ex post errors, such as mean error (ME), mean absolute deviation (MAD), mean absolute scaled error (MASE) and the author’s proposal (error D). The proposed technique, based on stochastic simulation, seems to be the least biased and most efficient. The Croston’s method gives positively biased predictions with rather low efficiency. The proposed forecasting technique might support decisions in enterprises facing the problem of forecasting intermittent demand. The more accurate forecasts could increase the quality of customer service and optimize the inventory level.
Comparison of Several Linear Ordering Methods for Selection of Locations in Order‑picking by Means of the Simulation Methods
Authors: Dmytrów Krzysztof
Published: October 2018

When a company uses a shared storage system, selection of locations during the order‑picking process is not an obvious task. Every location where the picked product is placed, can be described by means of several variables, such as: storage time, distance from the I/O point, degree of demand satisfaction, or the number of other picked products in the order. Therefore, the “attractiveness” of each location from the point of view of a certain order can be described by means of synthetic variable, on the basis of which a ranking is created. For each product, the decision‑maker selects the highest‑ranking locations and designates a route for the picker. In the article, by means of the simulation methods, results obtained by several classification methods will be compared. These methods are: Taxonomic Measure of Location’s Attractiveness (based on the Hellwig’s Composite Measure of Development), the TOPSIS method with the Euclidean and GDM distances and the Gen­eralised Distance Measure used as the composite measure of development.
Investment Risk Measurement Based on Quantiles and Expectiles
Authors: Trzpiot Grażyna
Published: October 2018

In the presented research, we attempt to examine special investment risk measurement. We use quantile regression as a model by describing more general properties of the response distribution. In quantile regression, we assume regression effects on the conditional quantile function of the response. In regression modelling, the focus is on extending linear regression (OLS), and in this paper we seek to apply expectile regression. The purpose of using both approaches is investment risk measurement. Both regression models are a version of least weighted squares model. The families of risk measures most commonly used in practice are the Value‑at‑Risk (VaR) and the Conditional Value‑at‑Risk (CVaR), which can be estimated by quantiles or expectiles in the tail of the response distribution.
Architectural Objects and Public Spaces Connected with Industry. A Contribution to the Discussion on Artistic and Aesthetic Values
Authors: Waryś Ewa
Published: October 2018

The article presents the contemporary cultural landscape of the historical workers’ settlements, located within the current administrative boundaries of the city of Katowice. Selected building complexes are standardized in terms of typology and building design, but differ in terms of the conservation status and forms of protection. The aim of the discussion is to show the relationship between the artistic and architectural aesthetics and public spaces related to the industry. The subject matter is an attempt to draw attention to the problem of the conservation status of most parts of the historical complexes of residential buildings in Upper Silesia, their untapped potential and declining values.
Among Prestigious Edifices – on Ceramic Decorations and Mosaics in Poland Post-WWII
Authors: Kostuch Bożena
Published: October 2018

Ceramic materials may have multifarious applications, the visual arts being one of them. Furthermore, they have been often used in architecture for decorative purposes. In Poland, the application of ceramics in architecture reached its peak of popularity in the post-WWII period. It was used in mosaics, reliefs, architectural and sculptural details, as well as combined with other materials, like glass or stone. Ceramics was applied for creating various small decorative forms but also large compositions that covered even several dozen or several hundred square metres, in buildings that served various functions, and were situated either indoors or on their external facades. Amongst these, there are buildings which were both important for local communities and became landmarks for particular sites, like modern hotels, railway stations, theatres, museums or academies. The paper is focused on compositions executed for such prestigious edifices.
Perception of Urban Habitat and the Structure of Human Interaction. Dialogues with the Artist as Part of Creative Intervention
Authors: Breska Katarzyna
Published: October 2018

In this paper I bring closer some of the aspects of my work, I show the approach to the space when working in public locations. The components of this approach are a careful observation of the environment, spending time with the locals, talking to them, taking into account the symbolic nature of the contents brought by the people. So I quote and comment some of the dialogues that happened between me and the passers by during a four week creative intervention in the city’s oldest street.
A General Framework for Ampliative Inference Patterns
Authors: Delrieux Claudio
Published: October 2018

Non trivial reasoning from contradictory premises is being acknowledged as one of the most important features in intelligent systems. Expert systems, planners and schedulers, and diagnosers, are almost always faced to potentially fallacious information, errors, uncertainty, and difference of opinions. In thesecases, we expect that the reasoning systems will not collapse. Instead, the rational expected behavior is to isolate the source of contradiction. Several systems for reasoning from contradictory premises have been advanced, usually within acontext of strict, monotonic knowledge. In this work we investigate how defeasible knowledge can be also handled in these systems. The key idea is to represent pieces of defeasible knowledge ordered within anepistemic importance relation. A semantic characterization is provided, and a sound and complete procedure to compute conclusions is also given. Then, we show how nonmonotonic reasoning and other patterns of ampliative inference like abduction and induction can be adequately recast within the general pattern of reasoning from contradiction. We discuss some applications, in particular, a brief formalization of scientific research programmes.
An Object-Oriented Frameworks-based Architecture for Decision Support Systems
Authors: Becker Karin , Bodart François
Published: October 2018

Reusability is considered to be the key for achieving productivity and quality in software, and much has been claimed about the particular contributions of the object-oriented paradigm towards the achievement of these goals. Object-oriented frameworks are coarse-grained reuse units, composed of a set of classes specifically designed to be refined and used as a group. In this paper, we discuss the nature of frameworks necessary to build a particular type of systems, namely Decision Support Systems (DSS), and their organization in a generic OO DSS multi-layer architecture. DSS are systems intended to improve the effectiveness of decision making, but information technologies can only have a major impact on decision making if techniques allowing the easy and rapid development of DSS are available. Much benefit is expected in terms of easiness and rapidity of development by constructing DSS from domain-oriented reusable components, as well as in terms of quality of DSS in this way developed.
Synonymic rows with loanwords in the Russian language
Authors: E Lin
Published: October 2018

Synonymic rows with loanwords are investigated. The study found that the change in the conceptual and linguistic worldview of modern man is largely due to the process of the emergence of new synonymic series in the Russian language. Synonymic relations between words are established on the basis of the dictionary synonymic definition of the already known word or phrase in the Russian language, with the help of already established in the Russian language borrowed nominations in the context of descriptive construction, illustrative material, which expands, presents the synonymic sphere of lexicographic definition. Human consciousness structures conceptual real reality anthropocentrically, so the semantic range of names of persons in the study material is quite wide. Examples of loanwords that characterize activities are presented. Based on the synonymic definition of terms in lexicographic sources, which reveals the meaning of a new loanword through the identical meaning of loanwords, it is assumed that in the understanding of the surrounding reality, a person uses words correlated with one concept or reality, and in this case there are synonymic series in which members of the opposition are loanwords and demonstrate the full identity.
Linguistic and culturological data of semiological analysis of existence modes within the framework of the union discourse
Authors: Andreeva Olga Nikolaevna
Published: October 2018

Particular attention is paid to the consideration of semantic-semiotic components of the existence of culture, the meanings of cultural phenomena and analysis of the semantics of discursive components. Within the framework of a single discourse, ontological focuses are realized as part of the so-called “modes of being”: “being in oneself”, “being for oneself”, “being for another”, each of which does not exist in isolation; between them there is continuous interaction and mutual development in the implementation of cultural scenarios. Modes are embodied in the language, they are directly involved in the process of creating the so-called cultural and linguistic picture of the world. The ontological nature of modes is appeared not only in their existence, development, but also in their embodiment, representation, in the transfer of meanings, in the semantic aspect of discourse. The embodiment of the modes of being in culture from the standpoint of semantic analysis considered in two ways: linguistic and cultural. Cultural parameter and its representation in the system of ontological knowledge should be considered as the functioning of such a semantic-semiotic phenomenon, such a transformation as “components of culture”, which are described from the standpoint of the semiological analysis, suggesting that when considering the components of culture as a cultural (linguocultural) text is based on the semantic aspect of the process of deployment of ritual actions in all the variety of components of lexical codes.
Mindset and Neological Worldview (on material of Tambov media)
Authors: E Lin
Published: October 2018

An attempt is made to consider the traditional problem of “neologism as the Russian national language phenomenon” wider – “neologism as a mental process phenomenon”, which determines the world perception through the Russian native language categories and forms. On the material of the “Tambov Life” newspaper neologisms are considered in the context of the neological worldview, which is a complex of neological human knowledge about the world, verbalized with new words; it is established that being a substantial element of the language worldview, the neological worldview participates in the formation of mentality, reflecting the innovative components in the lexical system of the language. The fact is given that the journalese style finds in new words the voice of this striking features, such as the focus on the impact of the reader, than the individuality of human perception of neologism, the principle of relationship to him is formed, reflecting the mentality as a variable category.
Native Adult Hip with Bacterial Septic Arthritis
Authors: Lum Zachary C. , Shieh Alvin K. , Meehan John P.
Published: October 2018

* Adult septic arthritis of the native hip can be difficult to diagnose; often, care is delayed >24 hours, which may result in a failure to preserve the joint.

* Treatment options include aspiration, open and arthroscopic irrigation and debridement, and resection arthroplasty with an antibiotic spacer and subsequent total hip arthroplasty.

* Risk factors for repeat irrigation and debridement include inflammatory arthritis, diabetes, synovial cell count of >85,000 cells/mL, and Staphylococcus aureus infection.

* Ten percent of patients undergoing resection arthroplasty and use of an antibiotic spacer may need an exchange spacer.

* Outcomes after use of an antibiotic spacer and staged total hip arthroplasty can be highly successful and rewarding.
Изменчивость счётных признаков сейсмосенсорной системы головы у разных видов пресноводных рыб и её связь с гидрохимическими факторами
Authors: Котегов Б. Г.
Published: October 2018

Изучались счётные морфологические признаки у трёх массовых видов рыб ― плотвы, речного окуня и золотого карася, обитающих в небольших искусственных водоёмах центрально-восточной части Удмуртии. У отловленных рыб произведён подсчёт числа отверстий сейсмосенсорных каналов в некоторых парных покровных костях скелета головы и вычислена сумма значений этих счётных признаков (ΣSS) с усреднением для левой и правой сторон. В исследованных водоёмах измерялась также общая минерализация воды и оценивалось содержание в воде ионов кальция и магния. Для изученных видов рыб выявлен общий тренд внутривидовой изменчивости: с увеличением концентрации Mg2+ в пресной воде уменьшалось среднее значение ΣSS в исследованных популяциях. Для популяций плотвы, окуня и карася, обитающих в водоёмах с наибольшими отличиями в содержании магния, отмечены статистически значимые различия средних величин и частотных распределений дискретных вариантов этого признака сейсмосенсорной системы. В дополнение к натурным исследованиям проведены лабораторные эксперименты по аквариумному выращиванию мальков окуня и плотвы в различных гидрохимических условиях. Сформированные в воде с повышенным содержанием Mg2+ мальки окуня и плотвы характеризовались меньшим числом отверстий в окостеневших сейсмосенсорных каналах головы по сравнению с таковым контроля, а также взрослых особей из материнских популяций. Повышенные концентрации Na+ не оказали подобного влияния на формирование изученных признаков. Для объяснения наблюдённых онтогенетических эффектов рассматривается возможность прямого влияния ионов магния на скорость развития личинок пресноводных рыб, а также косвенного влияния на их морфогенез конкурентных биохимических отношений этого элемента с кальцием.
Assessment of the banking system financial stability based on the differential approach
Authors: Kuznyetsova Anzhela , Pogorelenko Nataliya
Published: October 2018

In this paper, the banking system financial stability is assessed based on the differential approach. The differential approach provides for taking into account the specificity of the banking system structural organization (from the standpoint of the central bank and the second-level banks) and the sets of financial stability indicators, different in terms of their structure, and their volatility measures, according to this approach.The banking system financial stability is assessed based on the two groups of indicators: the first one characterizes the central bank financial stability (indicators of gross international reserves, effectiveness of monetary policy and foreign exchange regulation, ability to create favorable conditions in order to ensure the effectiveness of the banking sector); the second one defines the financial stability level for state banks, banks with private and foreign capital (indicators of the capital adequacy, liquidity, structure of assets and liabilities, effectiveness of the activity, financial risks). The differences between the sets of financial stability indicators for different groups of banks and the expediency of taking them into account during the assessment are revealed and substantiated according to the results of using the principal components method.The developed procedure of assessing the banking system financial stability provides for: constructing the banking system financial stability index (by multiplicative convolution of central bank financial stability subindex and three banks’ financial stability subindices); defining its high, medium and low level according to its quantitative values (according to interval scales, developed according to the rule “3σ”; interpreting the assessment results based on the scenario analysis, which is based on taking into account the dynamic change of the financial stability index during the analyzed period and allows to identify the state of the banking system (stable, conventionally stable or critical).
Life insurance companies marketing strategy in the digital world
Authors: Prymostka Olena
Published: October 2018

The research is aimed to evaluate the internet marketing strategies in of life insurance companies in Ukraine. The insurance service in the time of digitalization faces scenarios of implementation in the marketing strategy on-line component. The main challenge for Ukrainian life insurance companies comparatively with the world practice is non-obligatory status of such kind of insurance contracts. So, on the one hand, costs of operation, regulatory pressures and inflexible technology infrastructure are increasing, and, on the other hand, economic recession does not allow to increase the number of insured persons, premiums and profit growth.Sector of financial services is characterized by an increase in the level of competition, life insurance compelled to compete with pensions funds, banks and other financial institutions in order to defend their market share. Insurance companies marketing strategy determines how an insurer can best achieve its goals and objectives, keep existing customers and attract new ones with minimal costs.Keeping all the above problems around the study would attempt to study all the factors that contributed to the effective marketing strategies. This paper presents different marketing strategies that are taken up in life insurance services keeping in view external and internal environment of the company.
Cordycepin in Anticancer Research: Molecular Mechanism of Therapeutic Effects
Authors: Khan Md. Asaduzzaman , Tania Mousumi
Published: October 2018

Background:

Cordycepin is a nucleotide analogue from Cordyceps mushrooms, which occupies a notable place in traditional medicine.

Objective:

In this review article, we have discussed the recent findings on the molecular aspects of cordycepin interactions with its recognized cellular targets, and possible mechanisms of its anticancer activity.

Methods:

We have explored databases like pubmed, google scholar, scopus and web of science for the update information on cordycepin and mechanisms of its anticancer activity, and reviewed in this study.

Results:

Cordycepin has been widely recognized for its therapeutic potential against many types of cancers by various mechanisms. More specifically, cordycepin can induce apoptosis, resist cell cycle and cause DNA damage in cancer cells, and thus kill or control cancer cell growth. Also cordycepin can induce autophagy and modulate immune system. Furthermore, cordycepin also inhibits tumor metastasis. Although many success stories of cordycepin in anticancer research in vitro and in animal model, and there is no successful clinical trial yet.

Conclusion:

Ongoing research studies have reported highly potential anticancer activities of cordycepin with numerous molecular mechanisms. The in vitro and in vivo success of cordycepin in anticancer research might influence the clinical trials of cordycepin, and this molecule might be used for development of future cancer drug.
Flavonoids as P-gp Inhibitors: A Systematic Review of SARs
Authors: Cui Jiahua , Liu Xiaoyang , Chow Larry M.C.
Published: October 2018

P-glycoprotein, also known as ABCB1 in the ABC transporter family, confers the simultaneous resistance of metastatic cancer cells towards various anticancer drugs with different targets and diverse chemical structures. The exploration of safe and specific inhibitors of this pump has always been the pursuit of scientists for the past four decades. Naturally occurring flavonoids as benzopyrone derivatives were recognized as a class of nontoxic inhibitors of P-gp. The recent advent of synthetic flavonoid dimer FD18, as a potent P-gp modulator in reversing multidrug resistance both in vitro and in vivo, specifically targeted the pseudodimeric structure of the drug transporter and represented a new generation of inhibitors with high transporter binding affinity and low toxicity. This review concerned the recent updates on the structure-activity relationships of flavonoids as P-gp inhibitors, the molecular mechanisms of their action and their ability to overcome P-gp-mediated MDR in preclinical studies. It had crucial implications on the discovery of new drug candidates that modulated the efflux of ABC transporters and also provided some clues for the future development in this promising area.
Profile of HBV Integration in the Plasma DNA of Hepatocellular Carcinoma Patients
Authors: Li Weiyang , Cui Xiaofang , Huo Qing , Qi Yanwei , Sun Yuhui , Tan Meihua , Kong Qingsheng
Published: October 2018

Background:

Hepatitis B Viral (HBV) infection is one of the major causes of Hepatocellular
Carcinoma (HCC). Mounting evidence had provided that the HBV integration might be a critical
contributor of HCC carcinogenesis.

Objective and Methods: To explore the profile of HBV integration in the plasma DNA, the method of
next-generation sequencing, HBV capture and bioinformatics had been employed to screen for HBV
integration sites in the plasma samples.

Results:

In the initial experiment, a total of 87 breakpoints were detected in the 20 plasma samples.
The distribution of breakpoints showed that there was significant enrichment of breakpoints in the region
of intron. Furthermore, the HBV breakpoints were prone to occur in the region of X protein
(1,700-2,000bp) in the plasma samples. The pathway analysis had revealed that the HBV integrations
sites were specifically enriched in the cancer pathway.

Conclusion:

Altogether, our results had provided direct evidence for the HBV integration in plasma
DNA, and they might be potentially useful for future HCC prognosis and diagnosis.
Effect of the Interaction Between Hypertension and Cerebral White Matter Changes on the Progression of Alzheimer Disease
Authors: Chou Ping-Song , Kao Yi-Hui , Wu Meng-Ni , Chou Mei-Chuan , Chen Chun-Hung , Lin Ruey-Tay , Yang Yuan-Han
Published: October 2018

Background:

Cerebrovascular pathologies and hypertension could play a vital role in Alzheimer
disease (AD) progression. However, whether cerebrovascular pathologies and hypertension accelerate
the AD progression through an independent or interaction effect is unknown.

Objective:

To investigate the effect of the interactions of cerebrovascular pathologies and hypertension
on AD progression.

Method:

A retrospective longitudinal study was conducted to compare AD courses in patients with different
severities of cerebral White Matter Changes (WMCs) in relation to hypertension. Annual comprehensive
psychometrics were performed. WMCs were rated using a rating scale for Age-related WMCs
(ARWMC).

Results:

In total, 278 patients with sporadic AD were enrolled in this study. The mean age of the patients
was 76.6 ± 7.4 years, and 166 patients had hypertension. Among AD patients with hypertension,
those with deterioration in clinical dementia rating-sum of box (CDR-SB) and CDR had significantly
severe baseline ARWMC scales in total (CDR-SB: 5.8 vs. 3.6, adjusted P = 0.04; CDR: 6.4 vs. 4.4, adjusted
P = 0.04) and frontal area (CDR-SB: 2.4 vs. 1.2, adjusted P = 0.01; CDR: 2.4 vs. 1.7, adjusted P <
0.01) compared with those with no deterioration in psychometrics after adjustment for confounders. By
contrast, among AD patients without hypertension, no significant differences in ARWMC scales were
observed between patients with and without deterioration.

Conclusion:

The effect of cerebrovascular pathologies on AD progression between those with and without
hypertension might differ. An interaction but not independent effect of hypertension and WMCs on
the progression of AD is possible.
Curry Leaf and its Antioxidant Potential: A Systematic Study to Enhance its Activity in Aqueous Medium
Authors: Kumari Deepa , Mallick Tamanna , Karmakar Abhijit , Mondal Samiran , Das Sreeparna , Begum Naznin Ara
Published: October 2018

Background:

We have done a systematic study on the antioxidant activity of the methanol and petroleum ether (60-80°C) extracts (MEC and PEC respectively) of Curry leaves (Murraya koenigii Spreng. Family: Rutaceae) using various in-vitro chemical methods.

Methods:

Both of these two extracts were found to be highly efficient in the formation of Ag and Au nanoparticles. So, we have explored their ability to form the nanoparticles to study their antioxidant activity. In all the assay systems, MEC showed higher activity over PEC in aqueous medium. This may be due to the higher solubility of MEC and its active components, like polyphenols and flavonoids in the aqueous medium. PEC contains lesser amount of these water soluble active components but PEC was rich in carbazole types of alkaloids which are hydrophobic in nature. So, to enhance the antioxidant activity of PEC and its carbazole constituents, like 2-hydroxy carbazole and mahanimbine, we have encapsulated these in the biopolymeric matrix of the mucilage isolated from an edible vegetable, Abelmoschus esculentus L. (commonly known as Lady's finger, family: Malvaceae).

Results:

It was interesting to note that, PEC and its carbazole compounds showed better antioxidant activity (ferrous ion chelation and ferric reducing antioxidant activity) in aqueous medium after this encapsulation process.

Conclusion:

The protocols used in the present study were very simple and can be implemented in any lab set-up. In future, this work can be extended to evaluate antioxidant potentials of other plant based materials.
Risk Assessment of Sulphite Exposure through Foods Among Adolescents of Delhi (India)
Authors: Jain Arushi , Mathur Pulkit
Published: October 2018

Background:

Sulphites added as preservatives in food have been associated with adverse health effects in humans.

Objective:

The present study was designed with an objective of assessing the risk of sulphite exposure through food in adolescents (12-16 years old) of Delhi, India.

Methods:

A total of 1030 adolescents selected from four private and four government schools of Delhi, were asked to record their food intake using a 24 hour food record, repeated on three days, for assessing exposure to sulphites. The risk was assessed using six different scenarios of exposure.

Results:

The actual intake for sulphites for average consumers was 0.15 ± 0.13 mg / kg b.w. / day which was 21.4% of acceptable daily intake (ADI). For high consumers (P95), it was 65% of the ADI. However, for 2 respondents, the actual intake exceeded the ADI. The major food contributors to sulphite intake were beverage concentrates (46%), ready to serve beverages (22%) followed by miscellaneous food items (16%), mainly ice creams and snowballs. Estimation of sulphite intake using different exposure scenarios revealed that for certain scenarios where the highest reported sulphite level or maximum permissible levels were considered for calculation, the high consumers exceeded the ADI, though, for average consumers, intake was well below the ADI.

Conclusion:

Actual intake of sulphite for average consumers was well below the ADI but for high consumers was approaching the ADI. People with sulphite sensitivity need to be aware of hidden food sources of sulphites.
Biochemical and Pharmacological Applications of Essential Oils in Human Health Especially in Cancer Prevention
Authors: Ishfaq Pir Mohammad , Shukla Archana , Beraiya Satyaprakash , Tripathi Swati , Mishra Siddhartha K.
Published: October 2018

Background:

Essential oils (EOs) are aromatic, volatile and concentrated hydrophobic liquids extracted
from plant material. EOs are also called as ethereal oils, volatile oils or aetherolea. EOs also play a crucial
role in plant defence and signalling processes. They are mostly used in perfumes, cosmetics, soaps and other
products for flavouring food, drinks, adding scents to incense and household cleaning products. EOs have a long
medicinal history.

Methods:

Reported research literature and online contents related to the use of EOs for their biochemical pharmacological
applications in cancer prevention therapy were reviewed. The most relevant and updated citations
were included in this review.

Results:

This review elaborates the various types of EOs, their biochemical characteristics, and pharmacology.
Medicinal benefits of essential oil products range from various skin treatments to different types of therapies for
cancer and are dependent entirely on historical backgrounds of use of EOs for these properties. EOs have antimicrobial,
anticancer, antioxidant, antiparasitical, insecticidal, anti-inflammatory, viricidal, fungicidal, wound
healing, antihypertensive, analgesic properties and other medicinal properties. The efficiency of EOs in medical
treatments and treatment of cancers are these days a subject of interest in most countries.

Conclusion:

This review elaborated the potentials of EOs in regulating cancer cell growth and have explored the
probable EOs that can be used in drug development.
Review on the Characteristic, Properties and Analytical Methods of Cefquinomesulphate: ß-lactam Veterinary Drug
Authors: Shantier Shaza W.
Published: October 2018

Background:

Chemotherapy as a science began within the 1st decade of the twentieth
century with understanding of the principles of selective toxicity, the particular chemical relationships
between microorganism pathogens and medicines, the event of drug resistance, and also the
role of combined medical aid.

Objectives:

This review aims to highlight the characteristics, specifically the pharmacokinetic parameters
and the analytical methods reported in literature for the determination of Cefquinome, a
fourth generation cephalosporine used to treat Gram-positive and Gram-negative caused infections.

Conclusion:

Analysis of such drugs, whether used for the treatment of human or animal illness, is
essential in understanding the bioavailability and therapeutic control which will ensure their activity
and safety.