bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of body mass index and waist circumference in predicting of gestational diabetes mellitus, pregnancy induced hypertension and adverse pregnancy outcome amongst obese women
Authors: Anoohya Bhukya , Grover Suparna , Kaur Amrit P. , Padda Preeti , Kaur Jagdeep
Published: February 2025

Background: Risks to the pregnant women due to obesity during pregnancy include gestational diabetes, hypertensive disorders of pregnancy, sepsis, venous thromboembolism, stillbirth, preterm delivery, large for gestational age infant, cardiometabolic disease and obstructive sleep apnea. For the fetus, the risks include congenital anomalies, fetal growth restriction, macrosomia, prematurity, anomalies, and other adverse clinical outcomes. Thus, the aim of the present study was to the test hypothesis that waist circumference was as good as body mass index (BMI) to identify women at risk of obesity related complications during pregnancy.
Methods: 200 pregnant women in first trimester of pregnancy coming in antenatal outpatient department (OPD) of government medical college, Amritsar were recruited from October 2022 to March 2024. Patients were classified as obese/non obese as per Asian ethnicity specific threshold of waist circumference according to which waist circumference ≥80 cm is obese. Based on BMI women were classified as underweight, overweight and obesity. Overweight is a BMI ≥25 kg/m2; and obesity is a BMI ≥30 kg/m2. Pregnancies were followed up throughout pregnancy and final outcome were recorded and compared.
Results: Of the 200 participants, 13.5% were overweight, 4% were obese, another 10.5% were underweight and rest 72% had normal BMI. On the other hand, as per waist circumference the prevalence of obesity was 20% (waist circumference ≥80 cm), which was more than the combined prevalence (17.5%) of overweight (BMI=25-29.9) and obese (BMI ≥30) as per BMI. Both BMI >25 kg/m2 and waist circumference ≥80 cm are associated with increased odds of preterm labour gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), obstructed labour and SSI. It was statistically significant for GDM and HDP. Also, amongst women with >30 kg/m2 (obese), the odds of abortion and antepartum haemorrhage (APH) were increased significantly.
Conclusions: Both high BMI and waist circumference/80 cm are significant risk factors for development of GDM and hypertension. Maternal obesity defined by BMI >30 is a significant risk factor for abortion and APH. These two complications are not predicted by waist circumference.
Teaching and learning developmental anatomy: exploring google classroom engagement through preferred usage, behavioural intentions, and actual practices
Authors: Ramakrishna Roopashree
Published: February 2025

Background: In the 21st century researchers, trainers and teachers have begun to design and implement variety of teaching methodologies using online technology to improve traditional face-to-face teaching. Blended learning improves student engagement. In education, blended learning environment offers the convenience of the online environment without losing face-to-face teaching, and interaction with the learners. Objectives of the study were: to compare/estimate the difference the effective learning between the traditional pedagogy blended learning activities through eLearning; and to know the perception of the blended learning experience through eLearning in using google classroom site.
Methods: Regular classroom was used for traditional lecture and digital library for blended learning for the 1st MBBS students.
Results: In our study we found digital learning did improve students test score significantly. Students found blended learning helpful for learning the topics chosen in embryology. About 95% of the students strongly agreed to the fact that blended learning in digital library is conducive for learning the developmental anatomy.
Conclusions: During the study we found that blended learning environment is effective in teaching-learning embryology on students in terms of impact on learning and their perceived satisfaction. In the current study suggest that both preferred easy to use and preferred use positively affect the behavioral intention by undergraduates’ students who perceive the use of Google classrooms as easy and useful, and they are highly motivated toward the incorporation of such pedagogical tools in their learning process of developmental anatomy.
Assessing knowledge, attitude, and practice of adaptive designs in clinical trials among Indian stakeholders
Authors: Aithal Yashoda , Eldhose Merin , Shetty Yashashri , Sinha Soham , Gite Rucha
Published: February 2025

Background: This study attempted to evaluate the knowledge, attitudes, and practices of various stakeholders addressing adaptive clinical trials (ACT), as no analogous studies have been published in India.
Methods: Ethics committee (EC) approval was sought before circulating an online pre-validated questionnaire (28 questions in three domains) among 200 stakeholders involving the clinicians, clinical trial unit personnel, and medical advisors from various pharmaceutical industries. The responses collected were analysed using appropriate statistical tests. A p value <0.05 was considered significant.
Results: Out of the 200 participants surveyed, 169 responded, yielding a response rate of 84.5%. When the three distinct stakeholders’ median knowledge scores were evaluated, there was no statistically significant difference. The median knowledge score of stakeholders with more than five years of experience did not vary statistically from those with less than five years. In the attitude domain, 21.8% and 17.1% of participants agreed that the validity and integrity of research in ACT are hampered respectively. However, 73.9% felt that ACT has potential benefits while 79.2% believed they were underutilized. In the practice domain, only 4.7% of stakeholders have been a part of adaptive clinical trials.
Conclusions: The study found that fewer stakeholders participated in studies utilizing adaptive designs, which resulted in a decrease in knowledge, perception, and practices among the various stakeholders. This emphasizes the necessity for further educational initiatives in the future, such as planning conferences or training sessions, to raise the understanding of adaptable designs in clinical trials.
Lytic lesion in the little finger: a case report
Authors: Alhotan Saleh
Published: February 2025

Enchondroma is the most common benign tumor, affecting the phalanges and metacarpals. They are generally asymptomatic and discovered incidentally. This case report details the clinical presentation, X-ray imaging, and management of a solitary enchondroma affecting the middle phalanx of the little finger of the right hand. The diagnosis was confirmed with histopathological analysis of the retrieved specimen. The postoperative course showed smooth recovery with no complications. There was no recurrence at one year.
The effect of antiplatelet drugs on the management of cardiovascular diseases
Authors: Boralkar Rohan R. , Nilamwar Shweta S. , Mane Pranjali P. , Giri Ashok B.
Published: February 2025

Cardiovascular diseases (CVDs) are the leading global cause of mortality, necessitating innovative strategies for prevention, diagnosis, and treatment. Antiplatelet drugs play a vital role in mitigating adverse atherothrombotic events by inhibiting platelet aggregation, crucial for managing conditions such as myocardial infarction, ischemic stroke, and peripheral artery disease. Platelets, essential for haemostasis, also contribute to thrombus formation in vascular injury and disease. Their activation is triggered by stimuli like collagen, thrombin, and adenosine diphosphate (ADP). Antiplatelet drugs target these pathways to prevent arterial thrombosis. Key classes of antiplatelet agents include cyclooxygenase inhibitors, P2Y12 receptor antagonists, glycoprotein IIb/IIIa inhibitors, and phosphodiesterase inhibitors. Aspirin, a COX-1 inhibitor, irreversibly blocks thromboxane A2 production, effectively reducing recurrent cardiovascular events, though its role in primary prevention is tempered by bleeding risks. P2Y12 inhibitors, such as clopidogrel, prasugrel, and ticagrelor, suppress ADP-mediated platelet activation, with newer agents providing consistent efficacy but higher bleeding risk. Dual antiplatelet therapy, combining aspirin and a P2Y12 inhibitor, is the standard for acute coronary syndrome and post-PCI management. Challenges, including bleeding and resistance, underscore the need for personalized approaches using pharmacogenomics. Ongoing research aims to develop safer, targeted therapies, including thrombin receptor blockers and novel combination regimens.
A review of Hummā Danj (dengue fever) in Unani and conventional medicine
Authors: Imlaque Mohd , Husain Safder , Shewrwani Arish Mohammad Khan , Bibi Chand
Published: February 2025

The global burden of Hummā Danj dengue fever (DF) and its severe manifestations, such as dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS), has escalated significantly in recent decades. Dengue viruses, transmitted primarily by Aedes mosquitoes, pose a substantial public health challenge, with an estimated 50-100 million infections annually and significant mortality. While traditionally viewed as a childhood illness, there's emerging evidence of a shift towards older age groups experiencing more severe forms of the disease. Additionally, race, gender, rural settings and climate variability influence disease dynamics. Socioeconomic factors play a crucial role, with poorer countries facing greater challenges in disease prevention and control. The economic impact of dengue, akin to malaria, underscores the need for effective public health interventions. Improving case management, early detection and accurate monitoring are essential strategies. Diagnosis remains challenging due to variable test sensitivities and specificities. In Unani medicine, dengue fever is conceptualized within the framework of humoral pathology, with management focusing on symptomatic relief and supportive care. Overall, addressing the multifaceted challenges of dengue requires a comprehensive approach integrating medical, social and economic strategies.
Impact of bedbug’s infestation on use of mosquito nets in malaria control in Matayos, Busia, Kenya
Authors: Chebii Kiptanui , Injera Wilfred E. , Juma Kelvin K. , Odiwuor Collins A. , Ogombo Concilia
Published: February 2025

Background: Malaria is a significant public health problem in Kenya with more than 70% of its population at risk. The Kenya government has prioritized the provision of long-lasting insecticidal nets (LLINs) and insecticide treated nets (ITNS) in prevention of malaria. However; communities in Matayos, Busia County have shown reluctance in using them, that they harbor bed bugs. This study aims to establish the impact of bedbugs on use of mosquito nets in malaria control.
Methods: This was a cross-sectional study carried out at Murende community unit, Matayos, Busia Kenya. A questionnaire was used to collect data. Data analysis was done using SPSS; descriptive statistics were summarized as frequencies and proportions. Chi square was done to measure associations between variables.
Results: 77 (respondents) were included in the study. Majority (65%) were females (85%) reported having mosquito nets whereas 15% did not have mosquito nets.  Of the 85% with mosquito nets, 78% use them while 22% do not use them. 79% of those who don’t use mosquito nets claimed that mosquito nets harbored bedbugs. There is association between presence of bed bugs and use of mosquito nets (p=0.001), there is association between the level of education and presence of beg bugs (p=0.001)
Conclusions: Bedbug infestation is a barrier to consistent and persistent utilization of mosquito nets and has discouraged a bigger population from using them. Concerted effort towards the control of bedbugs has to be made if collateral benefit in malaria control by use of LLINs is to be achieved.
Environmental factors influencing hygiene practices among pupils in selected public primary schools in Kiambu County, Kenya
Authors: Ndungu Veronica , Juma Joseph , Mburu Samuel
Published: February 2025

Background: Hygiene practices, including hand washing with soap and water, are essential for preventing diseases like diarrhoea, especially in developing countries. Poor hygiene, inadequate water, and sanitation contribute to over 60% of the disease burden among students. This study investigates how hygiene promotion approaches, such as school-led sanitation programs, affect cleanliness practices among public primary school students in Kiambu County, Kenya.
Methods: Analytical cross-sectional study design was used and 121 participants in public primary schools from Gatundu South, Juja, Ruiru, and Kiambu sub-counties. Data was collected using administered structured questionnaire, and Key Informant Interview. Quantitative data analysis was conducted using SPSS version 29.0 and involved univariate and bivariate analysis. Qualitative data was analyzed by thematic content analysis.
Results: The study involved 121 respondents, aged 22-59 years (mean age 38.29±8.1), with 52.9% being female and 49.6% had undergraduate degrees, and 39.7% were senior teachers. The pupil-to-toilet ratio in the schools was 1:29, which did not meet the recommended standards for boys (1:36) but met the standard for girls (1:24). Hygiene promotion activities included parades (66.1%), classroom sessions (61.2%), and health clubs (60.3%). Factors like observing, demonstrating, and inspecting hygiene practices were strongly linked to improved handwashing, with ORs of 5.4, 8.8, and 5.8, respectively.
Conclusions: The study found strong associations between hygiene practices and implementors' expertise, with significant environmental factors influencing student hygiene. The public health and community health volunteers should take more active role in dissemination timely and accurate information on hygiene and health promotion.
Traditional ethnomedicinal practices for gynecological disorders among the Gond tribe of Chhattisgarh: a regional perspective
Authors: Kolla Andrea , Gawri Shobha , Kolla Varaprasad , Sahu Bharti
Published: February 2025

The Gond tribe, one of the largest tribal communities in India, is predominantly concentrated in Chhattisgarh, particularly in forest villages. Known for their rich cultural heritage and deep connection to nature, the Gonds rely heavily on the forests for their livelihood, including food, medicine, and materials for daily use. Traditional knowledge plays a crucial role in their healthcare, especially in addressing women's health issues. The Gond community has preserved its ancient practices of folk medicine, using a variety of medicinal plants to treat gynecological disorders such as menstrual irregularities, reproductive health concerns, and postpartum issues. This study focuses on the ethno-medicinal plants used by the Gond tribe for women's health in regions like Bilaspur, Gariyaband, Korba, and Saraipali. Through field surveys and interviews with local healers and community members, information was gathered on 34 plant species traditionally used for gynecological problems. Detailed data was compiled, including botanical names, plant families, local names, parts used, and medicinal properties. The Gonds utilize a diverse range of plants, preparing specific remedies for different gynecological issues, including menstrual disorders, fertility challenges, and menopause symptoms. Despite the availability of modern healthcare, these traditional remedies continue to be highly valued for their effectiveness. The findings of this study emphasize the importance of preserving indigenous knowledge and the need for conserving these valuable plant resources. It advocates for integrating traditional medicine with modern healthcare systems to improve women's health outcomes in the region and ensure the sustainability of this ethno-botanical knowledge.
A comparative study of National Family Health Survey-4 and National Family Health Survey-5 on quality of family planning services and unmet need for family planning indicators in Assam
Authors: Habib Ashfia , Sharma Sthapana , Saeed Aamir , Bhaisya Achyut C. , Ojah Jutika
Published: February 2025

Family planning is an important component of health, welfare, family stability as well as the social and economic progress of a community. The purpose of this study is to assess the shifts in the quality of family planning services and unmet needs in Assam based on National Family Health Survey (NFHS) rounds 4 and 5. The study is based on both NFHS-4 (2015-2016) and NFHS-5 (2019-2021) data and compares the major indicators; unmet need for family planning and quality of family planning services. Data disaggregated to district level were considered including total unmet need, demand for spacing, and the communication between health workers and female non-users regarding contraceptives. The current study shows that the overall total unmet need for family planning has declined in most of the districts in Assam when compared. However, when comparing districts large disparities have been found for certain districts demonstrating higher levels of unmet need. Contrary to this, the study established that the quality of family planning services measured by health worker’s interaction with non-users had increased in most districts but was still inadequate in the state. It is clear from the analysis that there has been significant improvement in family planning services, however; there are challenges concerning the use and availability of family planning services. Interventions proposed are strengthening interventions for certain groups, improving access, and increasing cultural competence.
Mejores gobiernos para mejores vidas: fortaleciendo las capacidades del Estado para una gestión estratégica, meritocracia e inclusiva del servicio civil en América Latina y el Caribe
Authors: Naranjo Bautista Sandra , Mosqueira Edgardo , Lafuente Mariano , De Michele Roberto , Fuenzalida Javier , Keefer Philip , Nunberg Barbara , Roseth Benjamin , Schuster Christian , Strazza Luciano
Published: February 2025

En un contexto de restricciones fiscales, desconfianza ciudadana y cambios tecnológicos acelerados, la tercera edición del estudio "Mejores gobiernos para mejores vidas” evalúa el estado del servicio civil en América Latina y el Caribe, resaltando los avances y desafíos de los últimos diez años. El libro responde a tres preguntas clave: (i) ¿Qué capacidades tienen los países para gestionar eficazmente su servicio civil? (ii) ¿Cuáles son los principales retos y cómo abordarlos? (iii) ¿Qué buenas prácticas se pueden adaptar para promover un servicio civil efectivo? A pesar de algunos avances, como la profesionalización gradual y la adopción de nuevas tecnologías, el progreso regional ha sido lento y desigual, con un crecimiento modesto en el índice global promedio. La publicación subraya la importancia de una gestión estratégica, meritocrática e inclusiva del talento humano como pilar central para fortalecer las capacidades estatales, mejorar la provisión de servicios públicos y aumentar la confianza ciudadana. Además, propone una hoja de ruta con recomendaciones específicas para consolidar un servicio civil más eficiente y equitativo, capaz de enfrentar los desafíos estructurales de la región.
THE IMPACT OF HIGHER EDUCATION ON IMPLEMENTATION OF THE SUSTAINABLE DEVELOPMENT CONCEPT
Authors: Arefieva Olena , Derhaliuk Marta , Bilyk Victoria , Kostiunik Olena , Shchepina Tetiana , Pohrebniak Anna
Published: February 2025

Modern global challenges include growth of environmental tension, irrational use of finite resources, which is due to constantly growing needs of society and the need to use resources to meet them. The sustainable development concept is global strategy for overcoming many problems of humanity and the direction for achieving social, economic and ecological balance. Higher education plays an important role in shaping consciousness of humanity about relevence of effective and conscious use of resources and ecological culture of the population. It is possible to strengthen the impact of higher education by implementing the sustainable development concept by introducing socially and environmentally oriented competencies of students, which will contribute to implementation of sustainable development principles in their future professional activities and everyday life. The purpose of the study is to identify the impact of higher education on implementation of the sustainable development concept through formation of socially and environmentally oriented competencies of students of higher education institutions. In the article, the methodology of the system-process approach is used, which makes it possible to consider specific features of higher education and sustainable development as processes of different nature using various methods of scientific knowledge and to determine their systematicity and mutual influence . Shortcomings inherent in the content, composition and implemention of educational programs at the level of higher education institutions are identified, regarding intensification of formation of professional socio-ecologically oriented competencies in students of higher educational institutions to ensure implementation of the sustainable development concept. Using the integrated approach in higher education institutions is justified, which covers theoretical and practical training of students in acquiring socio-ecologically oriented competencies , which includes development and implementation of educational programs that contribute to formation of necessary technical skills for specific professions, interdisciplinary knowledge that supports broader understanding of environmental processes, and normative competencies related to environmental awareness and values of sustainable development. Stages of organizational support for professional development of young specialists to implement the sustainable development concept and stages of formation of students' socio-ecological competencies are identified.
Towards Secure Information Systems: Developing and Implementing an Information Security Evaluation Model Using NIST CSF and COBIT 2019
Authors: Fadya Mifta , Utama Ditdit Nugraha
Published: February 2025

Ensuring information security in public sector information systems is now more important than ever. Advances in technology and information have not only made daily life easier, but also made the opportunities for cybercrimes vast and inevitable. This study aims to create a framework for evaluation that measure the maturity level of information security in information systems by integrating existing frameworks, NIST Cybersecurity Framework (CSF) and COBIT 2019. The result of this framework development is implemented in a public sector organization called PT XYZ, which has an information system as a tool to assist in the implementation of public services. The Capability Maturity Model Integration (CMMI) method is used to calculate the maturity level. The implemented approach resulted in information security maturity evaluation framework for information systems. This framework includes 118 activities which are divided into 23 categories. The distribution of the integration of the two frameworks contributes 61% activities, the NIST CSF contributes 8% and the COBIT 2019 framework contributes 31% activities. The measurement result of the information security maturity level in the information system at PT XYZ shows that all functions are at level 1 or the initial level. PT XYZ's low information security maturity reveals the critical need for stronger data protection and system resilience. This study introduces a novel approach to demonstrating a practical methodology for integrating two frameworks. The resulting framework enables public sector organizations to assess their security posture, identify areas for improvement, and enhance resilience against cyber threats, strengthening public service and safeguarding data.
Green Supply Chain Management: Create Competitive Advantage and Sustainability Performance
Authors: Linda Muthia Roza , Thabrani Gesit , Fitria Yuki , Firman Firman , Suhery Suhery , Sutiyem Sutiyem
Published: February 2025

This research aims to examine the relationship between green supply chain management (GSCM), sustainable performance (SP), and competitive advantage (CA). This research is based on a survey in the form of a questionnaire, and there were 60 respondents from 25 manufacturing enterprises in the city of Padang, consisting of managers and business owners. The data was examined utilizing the structural equation modeling (SEM) technique through the SmartPLS software. The research found a positive and significant direct effect of GM and ED (eco-design) against SP, GP, and ED against CA and CA against SP. They also found a positive and insignificant effect of GM on CA. Finally, the impact of GP on SP is negative and not significant. This research contributes to a further scientific understanding of adopting green practices by creating competitive advantage and its role in influencing sustainability performance.
Strategic Learning and Agility on Performance in Thai Hotels
Authors: Sungthong Sirinthra , Meesook Kanokwan , Aujirapongpan Somnuk , Agmapisarn Charoenchai , Yordudom Tanakrit
Published: February 2025

This study examined how strategic learning influenced Thai hotel businesses' financial performance in the contexts of world tourism destination and open innovation. Employing a quantitative approach with simple random sampling, data from 303 general managers were analyzed using structural equation modeling. Findings indicated that strategic knowledge creation and interpretation positively impacted financial performance, whereas strategic knowledge databases did not directly affect it. Moreover, strategic agility was not found to mediate the relationship between these knowledge processes and financial performance. These results accentuated the importance for Thai hotels and Thai tourism industry to adopt effective learning strategies tailored for the open innovation era, enhancing their ability to navigate business challenges and ultimately improve financial outcomes.
Leveling of Critical Thinking Abilities of Junior High School Students in Solving Geometry Problems
Authors: Suningsih Ari , Budayasa I Ketut , Ismail Ismail
Published: February 2025

The capacity for critical thinking varies among individuals and can be viewed as a spectrum from low to high. This qualitative study aimed to explore the development of critical thinking skills in junior high school students tackling geometry problems at SMPN 1 Ambarawa. It assessed components of logic (data, ideas, deduction, perspective) using intellectual norms (clarity, accuracy, thoroughness, relevance, logic, depth, breadth) as criteria. Data collection involved validation, task-based interviews, and written assessments, focusing on ninth-grade students in the 2022–2023 academic year. The findings revealed a range of critical thinking levels: level 2 (moderately critical), level 1 (less critical), and level 0 (minimally critical). Critical thinking is essential for solving geometry problems, and identifying students at different levels can promote equitable learning opportunities, ensuring no one is left behind in developing cognitive skills. These insights can also guide educational policies to enhance intellectual rigor in schools.
Bridging Motivation and Mastery: The Role of Self-Efficacy in Math Education
Authors: Amjad Amjad Islam , Malik Muhammad Abid , Aslam Sarfraz , Habib Musarrat
Published: February 2025

The main objective of this study was to examine new ways of assessing self-efficacy in learning mathematics that affect students' educational performance through perceived utility and intrinsic motivation. The study's research design was cross-sectional, consisting of 1232 elementary-level students. Data were collected using the Mathematics Motivation Scale (MMS), which was analyzed using SmartPLS4 and SPSS software. The authors concluded that SELPM partially mediates the relationship between the IMLM of the students and their PUM. The researchers suggest that teachers design effective teaching methodologies that significantly contribute to their (self-efficacy to learn and perform in mathematics) SELPM, (intrinsic motivation to learn mathematics) IMLM, and (perceived utility of mathematics) PUM. Future studies might be conducted to replicate the study's result and to explore the causes of the partially mediated effect of students' SEPM between their IMLM and PUM.
A Performance-Driven Exploration of Combining Topic Modeling and Machine Learning for Online Learning Data Analysis
Authors: Kulkanjanapiban Pachisa , Silwattananusarn Tipawan
Published: February 2025

The research aims to determine how well three clustering algorithms K-Means, hierarchical, and ensemble clustering work when combined with sophisticated topic modeling methods such as latent Dirichlet allocation (LDA), or nonnegative matrix factorization (NMF), and latent semantic analysis (LSA) on online learning datasets. The study’s data was scrapped from online learning resource platforms, i.e., Coursera, Udacity, edX, and FutureLearn in 2023and from Kaggle in 2021. Findings demonstrate that the LDA is more appropriate for the clustered data points generating topics. LDA-based clustering performs more efficiently than NMF-and LSA-based clustering when ensemble clustering is used. The proposed combination approach is beneficial when dealing with complicated education data with an ambiguous structure that requires interpretable insights. The study can reduce overfitting, identify more robust thematic clusters, and offer a powerful approach for unlabeled text analysis.
The folklore and mythological basis of the women’s quest in the Russian-language fantasy novel: To the statement of the problem
Authors:   Mari State University, Zolotova Tatiana A. , Akhmedzianova Almira R. ,   Mari State University
Published: February 2025

In the history of culture and literature, women have always played an important role. Numerous myths, folklore and literary works
show the importance of female characters in the content, functional and artistic solution of various problems. In recent decades, attention
to the “women’s issue” has certainly increased: representatives of various scientific disciplines are trying to identify the essence of the
phenomenon of “true femininity”. In popular literature, a new type of heroine is being formed – a girl undergoing her own set of challenges
(quest). On the one hand, it largely resembles the path of a male hero, on the other, it has its own specific features. In both cases, the female
quest has a pronounced folklore and mythological nature. The purpose of the study is to identify the folklore and mythological components
of the image of the new heroine in Russian language “female” fantasy novels. The research materials are Russian folk tales (35 plots), novels
by M. V. Semenova and A. V. Rubanov. The research methodology is based on the simultaneous application of the methods of analyzing the
structure of the folklore text by V. Y. Propp and J. Campbell, which allowed the authors to consider the path of the heroines in terms of both the functions they perform and the stages of the chosen path. As a result of the research, the term “women’s quest” was introduced, denoting
a folklore and mythological way of organizing the text of mass literature. In turn, fantasy novels are presented as coming-of-age novels with
the emphasis of stages similar to initiation rites in traditional culture.
Variability of the genre of autobiographical story in dialect and literary-colloquial speech (on the material of Saratov dialectological corpus)
Authors:   Saratov State University, Kamenskaya Yulia.V.
Published: February 2025

The article examines the specific features of how the genre of autobiographical story functions in dialect and literary-colloquial speech.
The study is conducted on the material of Saratov Dialectological Corpus and dictaphone recordings of native speakers of the literary language
of the corresponding age group. The characteristics of the autobiographical story common to dialect and literary-colloquial discourse were determined, and the factors influencing the functioning of this genre were identified – the level of communicative competence, correlation
with the genre of autobiography in business communication, interviewer’s questions structuring the story. In conversations with native
speakers of the literary language, a successful implementation of the communicative task was observed – to build an autobiographical story
in chronological order. In the autobiographical stories of dialect speakers, the chronological principle was often violated, the narration was
chaotic: a story about childhood or youth was suddenly interrupted by memories of adulthood, an assessment of the current situation, and
again returned to the past. A chronologically and event-consistent narrative in dialect discourse is most often determined by certain features
of the informant’s linguistic personality, for example, the experience of publicly telling about one’s life. A typical autobiographical narrative
of a dialect speaker is characterized by subjectivity (in accordance with the principle of egocentricity of dialect narration) and fragmentation, reflecting not all biographical stages, but the most important biographical points for the informant. In the text corpus, one can trace
the repeated reproduction of such key moments with minor variations in the records of one informant of different years. The retrospective
nature of the autobiographical story often contributes to the actualization of the strategy of self-presentation and self-identification. It was
revealed that the strategy of self-presentation of speakers of the two speech cultures has a similar nature; in self-identification, the professional principle is the leading one for speakers of the literary language, and the local and generic ones – for dialect speakers. Thus, the
variability of the genre of the autobiographical story is determined by both idiolectic, personal factors, and functioning in different types of
discourse – literary-colloquial and dialect ones.
Impacto de la terapia intravaginal con nistatina/dexametasona en la calidad de vida relacionada con la salud de mujeres con vulvovaginitis candidiásica o mixta
Authors: Romero Prada Martin Emilio , Díaz Cely Andrea Liliana , Caicedo Zúñiga Martha Lucia , Sánchez Guerrero Valentina , Rocha Rodríguez Luis Gabriel , Llanos Moreno Claudia Jimena , Vergel Pacheco Elkin Daniel , Castro Cuenca Carlos Giovani , Kafury Goeta Ana Cecilia
Published: February 2025

Objetivo: evaluar los síntomas y los cambios en la calidad de vida relacionada con la salud (CVRS) de pacientes con vulvovaginitis candidiásica o mixta, que recibieron tratamiento intravaginal con Nistatina/Dexametasona.
Métodos: estudio antes y después, realizado en mujeres mayores de 18 años con vulvovaginitis candidiásica o mixta, tratadas Nistatina/Dexametasona intravaginal en monoterapia o combinada con imidazol oral. Para evaluar la CVRS se utilizó el cuestionario EQ-5D y un cuestionario de síntomas, los cuales fueron aplicados antes y después del tratamiento.
Resultados: 236 pacientes fueron incluidas; 150 recibieron Nistatina/Dexametasona intravaginal (grupo 1) y 86 recibieron Nistatina/Dexametasona intravaginal e imidazol oral (grupo 2). La mediana de edad fue 35 años (RIC: 27- 43 años). Después del tratamiento, el tiempo de mejoría en los síntomas fue de 1 a 3 días en el 71.3 % (grupo 1) y 73.3 % (grupo 2), con un cambio de más del 80 %, en la mayoría de los aspectos evaluados. En el cuestionario EQ-5D, las dimensiones más afectadas fueron dolor (43 % grupo 1 vs. 30 % grupo 2), seguida por ansiedad/depresión (9 % grupo 1 vs. 19 % grupo 2), con una mejoría del índice EQ-5D antes y después del tratamiento en el grupo 1 (variación absoluta de 0.0589) y en el grupo 2 (variación absoluta de 0.0601).
Conclusión: se observó una mejoría temprana en los síntomas y la CVRS en pacientes tratadas con Nistatina/Dexametasona intravaginal, sin diferencias en los resultados entre la monoterapia y la combinación con imidazoles orales.
Reporte de caso del manejo anestésico en una reconstrucción aortica total, síndrome de Shone
Authors: Jiménez-Orduz Andrea , Mantilla-Gutiérrez Hugo , González-Plata David José , Camelo-Pardo Gianmarco
Published: February 2025

El síndrome de Shone es una rara entidad, la cual ocurre más frecuentemente en su forma incompleta, nosotros reportamos el caso de un adulto de 23 años masculino, quien ingresó por empeoramiento de disnea y disminución progresiva de su clase funcional, con hallazgos en la ecocardiografía transesofágica de coartación aórtica con válvula aórtica monocúspide, insuficiencia aórtica severa y gran dilatación de aorta desde raíz aórtica hasta la aorta descendente, esto, asociado a una hipertrofia ventricular izquierda con un patrón restrictivo severo. Al paciente se le realizó una reconstrucción aórtica total, lo cual representó un gran reto quirúrgico y anestésico desde la construcción del injerto aórtico hasta su egreso hospitalario, sin ninguna complicación presentada. El objetivo de este reporte es evidenciar la importancia de la valoración oportuna e integral del paciente, quien va a ser sometido a una cirugía cardiovascular.
Nomenclaturas e atribuições dos profissionais de apoio escolar nas redes estaduais brasileiras
Authors: Piovezan Camila Carlini Bonilha , Vilaronga Carla Ariela Rios
Published: February 2025

Em prol de garantir o direito e a aprendizagem dos estudantes da Educação Especial, atualmente as escolas brasileiras vivenciam a proposta de inclusão escolar e, entre os trabalhadores que atuam nesse contexto, tem-se o profissional de apoio escolar. A Lei Brasileira de Inclusão (2015) definiu seu exercício e sua atuação, prevendo as atividades de alimentação, higiene e locomoção. O objetivo do presente estudo é descrever e analisar as nomenclaturas e atribuições de profissional com o mesmo perfil previsto na Lei Brasileira de Inclusão, analisando os estados do Acre, Amapá, Espírito Santo, Goiás, Pará, Pernambuco, Paraná, Rondônia, Roraima, Rio Grande do Sul e Sergipe, observando se esses estados estão em consonância com o que é declarado pela Lei Brasileira de Inclusão. Para tanto, adotou-se o de pesquisa, sendo o tipo de pesquisa descritivo-exploratório, com base na análise documental. Os resultados indicaram que as legislações não são uniformes, pois nomeiam esses profissionais de formas diferentes, ainda que suas atribuições sejam semelhantes. Mostraram a urgência de discussão a respeito dos critérios de seleção desses profissionais em consenso com os estudos assinalados na educação especial brasileira. Conclui-se que a inexistência de uma lei específica que contemple os profissionais de apoio escolar tem culminado na desregulamentação jurídica, podendo acarretar barateamento, precarização e enfraquecimento desse tipo de função, tão relevante no cenário da educação especial brasileira.
Perpassando o recreio escolar pelo viés da Teoria Ator-Rede
Authors: Mercês Simone Santos de Oliveira das , Silva Cayo Vinicius Honorato da
Published: February 2025

Este artigo tem como objetivo investigar o recreio escolar e as relações estabelecidas por meio das redes sociotécnicas entre humanos e não humanos nesse espaço-tempo por meio da Teoria Ator-Rede (TAR). No espaço-tempo destinado ao recreio escolar, acontece o brincar livre, em que as crianças podem utilizar brinquedos, elementos da natureza e objetos os mais diversos para interagir com outras crianças, adultos e também com os próprios objetos. Nesse sentido, apresentam-se as associações e redes estabelecidas entre brinquedo e brincadeiras no recreio escolar, espaço-tempo este de aprendizado e associações entre humanos e não humanos. Constatou-se uma carência de publicações que relacionem e compreendam os humanos e não humanos no recreio escolar tendo como suporte a TAR.
A avaliação da aprendizagem em cursos de licenciatura em Educação Física: percepções de coordenadores de curso, professores e alunos
Authors: Moreira Raquel Stoilov Pereira , Ferraz Osvaldo Luiz
Published: February 2025

O objetivo deste estudo foi identificar as percepções dos coordenadores de curso, professores e alunos em relação às concepções e práticas da Avaliação da Aprendizagem nos cursos de licenciatura em Educação Física. Este estudo descritivo, com abordagem qualitativa, ocorreu em seis Instituições de Ensino Superior (IESs) localizadas em Mato Grosso que oferecem curso de licenciatura em Educação Física, contando com a participação de seis coordenadores de curso, 36 professores e 85 alunos. Como instrumentos de pesquisa adotamos questionários com professores e alunos e entrevista em pautas com coordenadores de curso. Para tratar os dados, adotamos a análise de conteúdo temático categorial proposta por Bardin (2016), tendo como apoio o software NVivo. Entre os resultados, destacamos: equívocos conceituais dos professores em relação à avaliação da aprendizagem; divergências entre as concepções de avaliação de coordenadores, professores e alunos; distanciamento entre a percepção das práticas avaliativas entre professores e alunos. Ressaltamos a importância das IESs fortalecerem os processos de formação continuada de seus professores, bem como reverem o processo de formação inicial, a fim de melhor subsidiar o trato didático metodológico da avaliação nas IESs.
Vivências e desafios da universidade pública hoje: ensino remoto e presencial no Ensino Superior
Authors: Theodoro Débora Luana Crestani , Soares Nandra Martins , Rossetto Elisabeth , Peron Andreia
Published: February 2025

A implantação do ensino remoto impactou as vivências de professores e estudantes no Ensino Superior, como o distanciamento no contato interpessoal. Diante dessa realidade, busca-se, por meio deste trabalho, discutir sobre as práticas que resultam desse cenário, tendo como objetivo principal problematizar a referida temática, inserindo-a na discussão da universidade pública na atualidade, e as vivências resultantes da crescente utilização das tecnologias da informação e da comunicação (TICs) nos contextos educacionais. Nessa perspectiva, objetiva-se ainda analisar o fenômeno da pandemia da Covid-19 e algumas de suas repercussões na esfera educacional. O trabalho envolveu uma investigação exploratória desenvolvida a partir de uma pesquisa bibliográfica baseada nos pressupostos epistemológicos da Psicologia Histórico-cultural, adentrando no estudo de aspectos políticos do Ensino Superior público brasileiro. Deste artigo, apreende-se que o ensino remoto e a virtualização das atividades de ensino impuseram aos ambientes de Ensino Superior públicos metodologias de trabalho inovadoras, visto que a cultura tecnológica presente em nossa sociedade remete a novos desafios, embora apresente limitações no que se refere à sua efetivação, e devendo ser utilizadas de forma consciente, de modo a evitar a segregação social.
Screening studies of the psychotropic activity of regulatory peptides under conditions of thyroid hyperfunction
Authors: Sergalieva M. U. , Tsibizova A. A. , Samotrueva M. A. , Andreeva L. A. , Myasoedov N. F.
Published: February 2025

The work is devoted to the screening study of the psychotropic activity of regulatory peptides of a number of glyprolins and melanocortins in conditions of thyroid hyperfunction.

   Material and methods. The study was carried out on male rats divided into groups: I – intact rats (control); II – individuals with experimental hyperthyroidism; III, IV, V, VI, VII and VIII – animals with induced hyperthyroidism receiving Thr-Lys-Pro-Arg-Pro-Gly-Pro, ACTH(4-7)-Pro-Gly-Pro, ACTH(6-9)-Pro-Gly-Pro, Pro-Gly-Pro, Pro-Gly-Pro-Leu, Arg-Pro-Gly-Pro, Pro-Gly-Pro-Val and Met-Thr-Lys-Pro-Arg-Pro-Gly-Pro, respectively. The behavioural activity of rodents was studied using the «Open Field» test.

   Results and its discussion. It was found that in the group of rats with induced hyperthyroidism there was an increase in chaotic, disorderly motor activity against the background of a decrease in orienteering and exploratory (crossing the centre, examination of burrows) and an increase in the level of anxiety (defecation, grooming, freezing). The investigated melanocortin and glyproline compounds against the background of thyroid dysfunction had to a greater or lesser extent a corrective effect on the behavioural status of laboratory animals.

   Conclusions. The results of the screening study of psychotropic activity of glyproline and melanocortin peptides under conditions of thyroid hyperfunction testify to the fact that that the compounds Thr-Lys-Pro-Arg-Pro-Gly-Pro and Met-Thr-Lys-Pro-Arg-Pro-Gly-Pro show the most pronounced effect on behavioural parameters in the «Open Field» test at intraperitoneal administration at doses of 87 and 88 µg/kg/day equal to 1/10 of their molecular weight.
Duration and dispersion of QT interval in patients with liver cirrhosis: diagnostic and prognostic value
Authors: Genkel V. V. , Pospelov V. N. , Kuznetsova A. S. , Smagina N. V. , Vedernikova E. O. , Ashmarina S. M. , Shaposhnik I. I.
Published: February 2025

The data on the prognostic significance and relationship of the prolonged QT syndrome with the risk of cardiac rhythm disturbances in liver cirrhosis are contradictory. One of the directions of further research in this area is to study the significance of other electrocardiographic parameters reflecting ventricular repolarization disturbance in patients with liver cirrhosis.

   Aim of the study was to investigate diagnostic and prognostic value of electrocardiographic parameters reflecting changes in heart electrical systole and heterogeneity of ventricular repolarization in relation to the presence of terminal liver cirrhosis and development of adverse outcomes in patients with established diagnosis of liver cirrhosis.

   Material and methods. The study included 35 patients with an established diagnosis of liver cirrhosis and 20 comparison group individuals matched by gender (p = 0.550) and age (p = 0.376). The severity of liver cirrhosis was assessed using the MELD and Child-Turcotte-Pugh scales. All patients had ECG recorded and analyzed on a Poli-Spectrum-8/E electrocardiograph (Neurosoft LLC, Ivanovo).

   Results. Patients with liver cirrhosis had significantly longer QTc interval durations than those in the comparison group (458.0 [432.5; 482.7] and 418.5 [405.0; 432.0] ms, respectively) (median [25th percentile; 75th percentile]) and smaller absolute and relative to QT interval Tpeak-Tend interval values. The severity of liver cirrhosis, as determined by the MELD scale, was directly correlated with QTc (r = 0.355; p = 0.0396), QTd (r = 0.389; p = 0.0228) and QTcd (r = 0.382; p = 0.0257) interval duration. The follow-up period was 3.96 [1.50; 8.59] months. Death from cirrhosis-related causes was recorded in 12 (34.3 %) patients. Among the electrocardiographic parameters investigated, the addition of QTc interval duration to the MELD scale in the prognostic model made it possible to increase the model performance and achieve statistical significance (area under the curve 0.763 (95 % confidence interval 0.633–0.894), p = 0.0088).

   Conclusions. Patients with liver had higher QTc values than those in the comparison group and lower Tpeak-Tend, Tpeak-Tend/QT and Tpeak-Tend/QTc values. The severity of liver cirrhosis, as determined by the MELD scale, was associated with an increase in QTc, QTd and QTcd duration. Adding QTc interval duration to the MELD scale allowed for the increase in the performance of the all-cause mortality prediction model.