bluuebunny/crossref_metadata_2025 huggingface dataset:
Donations for Refugee Crises: In-kind vs. Cash Assistance
Authors: Kotsi Telesilla O. , Wu Owen Q. , Pedraza-Martinez Alfonso J.
Published: February 2022

Problem definition: Six million refugees have been living in camps in 2021 due to multiple armed conflicts worldwide. Regulations often impede refugees’ integration into host countries; thus, refugees have to seek help from humanitarian organizations (HOs). HOs traditionally provide in-kind (e.g., food) assistance and now offer cash (monetary assistance) that refugees can spend at local retail stores. However, cash assistance can be exploited by local retailers’ market power, which challenges HOs’ mission of helping refugees while doing no harm to host communities. Practical relevance: Completely informed by field research in three refugee camps in northwestern Greece, we analyze the trade-off between in-kind and cash assistance from the perspective of an HO. We propose two cash assistance policies, implementable by a partnership between the HO and the local government, to curb the retailer’s market power and ensure that the refugees, the local residents, and the retailer are better off than if only in-kind assistance is provided. Methodology: We use field research to define our research setting and support our main modeling assumptions and parameters. Then, we use a game-theoretical model to analyze the interactions among multiple stakeholders in an ecosystem consisting of an HO, refugees, a monopolistic retailer, local residents, and a local government. Results: We demonstrate the effectiveness of our proposed cash assistance policies that benefit refugees and local residents while ensuring the retailer’s profitability. In particular, a price-dependent cash assistance (PDCA) policy aligns the incentives between the retailer and the HO-government partnership. This new policy for cash assistance acts as a lever for the retailer to voluntarily set desirable prices, which benefit both refugees and their host community. Managerial implications: We provide tools and implementable policies that guide HOs to improve their budget allocation between in-kind and cash assistance for refugees living in areas where local market power exists. Moreover, we clearly outline the roles of HOs and the local government in a partnership for cash assistance to refugees.

History: This paper has been accepted for the Manufacturing & Service Operations Management Special Section on Responsible Research in Operations Management.

Funding: T. O. Kotsi thanks the Onassis Foundation (Greece) for financial support.

Supplemental Material: The e-companion is available at https://doi.org/10.1287/msom.2021.1073 .
Miscarriage
Authors: Winter George F
Published: February 2022

George F Winter examines issues surrounding miscarriage and stillbirth, including how the lack of paid leave and how language and behaviour can impact parents after such a loss
Enhance your career
Authors: Bissett Julie
Published: February 2022

Julie Bissett discusses six ways to improve your skill set – and add value to your practice
Motivation and Grit Affects Undergraduate Students’ English Language Performance
Authors: Wu Yun Tao , Foong Lydia Yoke Yean , Alias Noryati
Published: February 2022

This study aims to explore non-English speaking major student’s perceptions of Motivation and Grit and the relationship between these two factors and students’ English language performance at a public university in China. The research was conducted by quantitative research design to collect 624 non-English speaking Major students’ answers to multiple questionnaires at a public university in China. Data analysis is used by SPSS and AMOS. The study shows that Motivation and Grit all have a positive correlation with English language performance. One major conclusion of this study is Grit has the most significant effect on the English language performance of non-English speaking major students in multiple regression analysis and is also the best predictor of the relationship between these two factors and English language performance in the path analysis in Structure Equation Modeling (SEM) analysis. The finding also revealed that male students’ perception of motivation and grit is slightly stronger than that of female students. These findings highlight the need for English as a foreign language (EFL) teacher to understand students’ affective factors in learning English, and hence help them utilize different teaching methods to enhance students’ English learning and promote sustainable development of English learning in a public Chinese university.
How Students Use Cognitive Structures to Process Information in the Algebraic Reasoning?
Authors: Basir Mochamad Abdul
Published: February 2022

Cognitive processes are procedures for using existing knowledge to combine it with new knowledge and make decisions based on that knowledge. This study aims to identify the cognitive structure of students during information processing based on the level of algebraic reasoning ability. This type of research is qualitative with exploratory methods. The data collection technique used began by providing a valid and reliable test instrument for algebraic reasoning abilities for six mathematics education student programs at the Islamic University of Sultan Agung Indonesia. Subjects were selected based on the level of upper, middle, and lower algebraic reasoning abilities. The results showed that (1) students with the highest level of algebraic reasoning ability meet the logical structure of Logical Reasoning which shows that students at the upper level can find patterns and can generalize; (2) Students at the intermediate level understand the cognitive structure of Symbolic Representations, where students can make connections between knowledge and experience and look for patterns and relationships but have difficulty making rules and generalizations; (3) students at lower levels understand the cognitive structure of Comparative Thinking, where students are only able to make connections between prior knowledge and experience.
Multilineage-differentiating Stress-enduring (MUSE) Cells in Orthobiologics: Are they the Future?
Authors: Alentorn-Geli Eduard , Laiz Patricia , Ferré-Aniorte Alfred , Seijas Roberto , Barastegui David , Álvarez-Díaz Pedro , Cuscó Xavier , Sánchez Cristina , García Luís , García-Balletbó Montse , Cugat Ramón
Published: February 2022

Multilineage-differentiating stress-enduring (MUSE) cells are non-tumorigenic pluripotent stem cells with endogenous reparative properties. These cells have a very powerful ability to adapt to global environment changes and are thus stress-tolerant cells. Interestingly, MUSE cells can differentiate into cells representative of all three germ layers. There has been a number of studies demonstrating its powerful regenerative power in several disorders: type-1 diabetes mellitus, myocardial infarction, stroke, glomerular-related kidney diseases, chronic liver failure, and ischemia-reperfusion lung injury. Recent data have also suggested that MUSE cells have significant repair properties for osteochondral lesions. The present article will review what are MUSE cells and how they work, the application of these cells into different disorders, and the studies up-to-date regarding MUSE cells in orthobiologic. Keywords: Muse cells, stem cells, regenerative, regeneration.
In vivo PS-OCT needle probe scan of human skeletal muscle
Authors: McBride Jeffrey M. , Hackmann Michael J. , Nimphius Sophia , Cense Barry
Published: February 2022

Polarization-sensitive optical coherence tomography (PS-OCT) derived
birefringence values effectively identify skeletal muscle structural
disruption due to muscular dystrophy and exercise-related muscle
damage in animal models in ex vivo tissue. The
purpose of this investigation was to determine if a PS-OCT needle
probe inserted into the leg of a human subject could accurately
identify various anatomical structures with implications for use as a
diagnostic tool for the determination of skeletal muscle pathology. A
healthy middle-aged subject participated in this study. A custom-built
PS-OCT system was interfaced with a side-viewing fiber-optic needle
probe inserted into the subject’s vastus lateralis muscle via a
motorized stage for 3D data acquisition via rotation and stepwise
pullback. The deepest recorded PS-OCT images correspond to a depth of
6 mm beneath the dermis with structural images showing uniform,
striated muscle tissue. Multiple highly birefringent band-like
structures with definite orientation representing connective tissue of
the superficial aponeurosis appeared as the depth of the needle
decreased. Superficial to these structures the dominating appearance
was that of adipose tissue and low birefringent but homogeneous
scattering tissue. The data indicate that a PS-OCT needle probe can be
inserted into live human skeletal muscle for the identification of
relevant anatomical structures that could be utilized to diagnose
significant skeletal muscle pathology.
Quantitative Jones matrix imaging using vectorial Fourier ptychography
Authors: Dai Xiang , Xu Shiqi , Yang Xi , Zhou Kevin C. , Glass Carolyn , Konda Pavan Chandra , Horstmeyer Roarke
Published: February 2022

This paper presents a microscopic imaging technique that uses variable-angle illumination to recover the complex polarimetric properties of a specimen at high resolution and over a large field-of-view. The approach extends Fourier ptychography, which is a synthetic aperture-based imaging approach to improve resolution with phaseless measurements, to additionally account for the vectorial nature of light. After images are acquired using a standard microscope outfitted with an LED illumination array and two polarizers, our vectorial Fourier ptychography (vFP) algorithm solves for the complex 2x2 Jones matrix of the anisotropic specimen of interest at each resolved spatial location. We introduce a new sequential Gauss-Newton-based solver that additionally jointly estimates and removes polarization-dependent imaging system aberrations. We demonstrate effective vFP performance by generating large-area (29 mm2), high-resolution (1.24 μm full-pitch) reconstructions of sample absorption, phase, orientation, diattenuation, and retardance for a variety of calibration samples and biological specimens.
Vector light field display based on an intertwined flat lens with large depth of focus
Authors: Zhou Fengbin , Zhou Feng , Chen Yang , Hua Jianyu , Qiao Wen , Chen Linsen
Published: February 2022

The depth of focus (DOF) of a lens is a crucial parameter in glasses-free 3D displays that affects the viewing distance range. Here we proposed a vector light field display based on intertwined flat lens for extended viewing distance. The gray-scale diffractive lens (GDL) is designed and fabricated with extended DOF for red (658 nm), green (532 nm), and blue (450 nm) colors. By integrating the intertwined GDLs with a liquid crystal display, four views form a smooth horizontal parallax with a cross talk below 26% over a viewing distance from 24 to 90 cm. The enhancement of the DOF is

1.8

×

1

0

4

-fold. The light efficiency of the pixelated GDL reaches 82%. The proposed vector light field 3D display has the advantages of a thin form factor, high efficiency, high color fidelity, and large viewing distance. The potential applications include portable electronics, 3D TVs, and tabletop displays.
Phase retrieval framework for direct reconstruction of the projected refractive index applied to ptychography and holography
Authors: Wittwer Felix , Hagemann Johannes , Brückner Dennis , Flenner Silja , Schroer Christian G.
Published: February 2022

The interaction of an object with a coherent probe often encodes its properties in a complex-valued function, which is then detected in an intensity-only measurement. Phase retrieval methods commonly infer this complex-valued function from the intensity. However, the decoding of the object from the complex-valued function often involves some ambiguity in the phase, e.g., when the phase shift in the object exceeds

2
π

. Here, we present a phase retrieval framework to directly recover the amplitude and phase of the object. This refractive framework is straightforward to integrate into existing algorithms. As examples, we introduce refractive algorithms for ptychography and near-field holography and demonstrate this method using measured data.
People’s desire to be in nature and how they experience it are partially heritable
Authors: Chang Chia-chen , Cox Daniel T. C. , Fan Qiao , Nghiem Thi Phuong Le , Tan Claudia L. Y. , Oh Rachel Rui Ying , Lin Brenda B. , Shanahan Danielle F. , Fuller Richard A. , Gaston Kevin J. , Carrasco L. Roman
Published: February 2022

Nature experiences have been linked to mental and physical health. Despite the importance of understanding what determines individual variation in nature experience, the role of genes has been overlooked. Here, using a twin design (TwinsUK, number of individuals = 2,306), we investigate the genetic and environmental contributions to a person’s nature orientation, opportunity (living in less urbanized areas), and different dimensions of nature experience (frequency and duration of public nature space visits and frequency and duration of garden visits). We estimate moderate heritability of nature orientation (46%) and nature experiences (48% for frequency of public nature space visits, 34% for frequency of garden visits, and 38% for duration of garden visits) and show their genetic components partially overlap. We also find that the environmental influences on nature experiences are moderated by the level of urbanization of the home district. Our study demonstrates genetic contributions to individuals’ nature experiences, opening a new dimension for the study of human–nature interactions.
The “Ecosystem as a Service (EaaS)” approach to advance clinical artificial intelligence (cAI)
Authors: Ishii-Rousseau Julian Euma , Seino Shion , Ebner Daniel K. , Vareth Maryam , Po Ming Jack , Celi Leo Anthony
Published: February 2022

The application of machine learning and artificial intelligence to clinical settings for prevention, diagnosis, treatment, and the improvement of clinical care have been demonstrably cost-effective. However, current clinical AI (cAI) support tools are predominantly created by non-domain experts and algorithms available in the market have been criticized for the lack of transparency behind their creation. To combat these challenges, the Massachusetts Institute of Technology Critical Data (MIT-CD) consortium, an affiliation of research labs, organizations, and individuals that contribute to research in and around data that has a critical impact on human health, has iteratively developed the “Ecosystem as a Service (EaaS)” approach, providing a transparent education and accountability platform for clinical and technical experts to collaborate and advance cAI. The EaaS approach provides a range of resources, from open-source databases and specialized human resources to networking and collaborative opportunities. While mass deployment of the ecosystem still faces several hurdles, here we discuss our initial implementation efforts. We hope this will promote further exploration and expansion of the EaaS approach, while also informing or realizing policies that will accelerate multinational, multidisciplinary, and multisectoral collaborations in cAI research and development, and provide localized clinical best practices for equitable healthcare access.
Data quality of reported child immunization coverage in 194 countries between 2000 and 2019
Authors: Rau Cornelius , Lüdecke Daniel , Dumolard Laure B. , Grevendonk Jan , Wiernik Brenton M. , Kobbe Robin , Gacic-Dobo Marta , Danovaro-Holliday M. Carolina
Published: February 2022

Analyzing immunization coverage data is crucial to guide decision-making in national immunization programs and monitor global initiatives such as the Immunization Agenda 2030. We aimed to assess the quality of reported child immunization coverage data for 194 countries over 20 years. We analyzed child immunization coverage as reported to the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) between 2000–2019 by all WHO Member States for Bacillus Calmette-Guérin (BCG) vaccine birth dose, first and third doses of diphtheria-tetanus-pertussis-containing vaccine (DTP1, DTP3), and first dose of measles-containing vaccine (MCV1). We assessed completeness, consistency, integrity, and congruence and assigned data quality flags in case anomalies were detected. Generalized linear mixed-effects models were used to estimate the probability of flags worldwide and for different country groups over time. The probability of data quality flags was 18.2% globally (95% confidence interval [CI] 14.8–22.3). The lowest probability was seen in South-East Asia (6.3%, 3.3–11.8, p = 0.002), the highest in the Americas (29.7%, 22.7–37.9, p < 0.001). The probability of data quality flags declined by 5.1% per year globally (3.2–7.0, p < 0.001). The steepest decline was seen in Africa (-9.6%, -13.0 to -5.8, p < 0.001), followed by Europe (-5.4%, -9.2 to -1.6, p = 0.0055), and the Americas (-4.9%, -9.2 to -0.6, p = 0.026). Most country groups showed a statistically significant decline, and none had a statistically significant increase. Over the past two decades, the quality of global immunization coverage data appears to have improved. However, progress has not been universal. The results highlight the need for joint efforts so that all countries collect, report, and use high-quality data for action in immunization.
Computer-vision object tracking for monitoring bottlenose dolphin habitat use and kinematics
Authors: Gabaldon Joaquin , Zhang Ding , Lauderdale Lisa , Miller Lance , Johnson-Roberson Matthew , Barton Kira , Shorter K. Alex
Published: February 2022

This research presents a framework to enable computer-automated observation and monitoring of bottlenose dolphins (Tursiops truncatus) in a zoo environment. The resulting approach enables detailed persistent monitoring of the animals that is not possible using manual annotation methods. Fixed overhead cameras were used to opportunistically collect ∼100 hours of observations, recorded over multiple days, including time both during and outside of formal training sessions, to demonstrate the viability of the framework. Animal locations were estimated using convolutional neural network (CNN) object detectors and Kalman filter post-processing. The resulting animal tracks were used to quantify habitat use and animal kinematics. Additionally, Kolmogorov-Smirnov analyses of the swimming kinematics were used in high-level behavioral mode classification. The object detectors achieved a minimum Average Precision of 0.76, and the post-processed results yielded 1.24 × 107estimated dolphin locations. Animal kinematic diversity was found to be lowest in the morning and peaked immediately before noon. Regions of the zoo habitat displaying the highest activity levels correlated to locations associated with animal care specialists, conspecifics, or enrichment. The work presented here demonstrates that CNN object detection is viable for large-scale marine mammal tracking, and results from the proposed framework will enable future research that will offer new insights into dolphin behavior, biomechanics, and how environmental context affects movement and activity.
Prevalence of stunting and its associated factors among children 6–59 months of age in pastoralist community, Northeast Ethiopia: A community-based cross-sectional study
Authors: Gebreayohanes Mulugeta , Dessie Awrajaw
Published: February 2022

Introduction

Globally, stunting is a significant public health concern and it is very critical in Ethiopia. This research aims to determine the prevalence of stunting and its correlates among children in the pastoral community.

Methods

A community-based cross-sectional study was conducted in Dubti District, Afar Region, North East Ethiopia from 2–31 January 2018. A total of 554 children were recruited using a multi-stage sampling technique and participated in this study. A binary logistic regression analysis was performed to determine factors linked to stunting. The significance of the associations was determined at a p-value < 0.05 and the adjusted odds ratio at 95% CI was calculated to evaluate the strength of the associations.

Results

The prevalence of stunting was 39.5% (95% CI: 35.4–43.5%). The odds of stunting were increased, so does the age of the child increased as compared to 6–11 months of children. Initiating breastfeeding after 1 hour after birth (AOR = 1.99; 95% CI: 1.22, 3.23), not exclusively breastfeeding for at least 6 months (AOR = 2.57; 95% CI: 1.49, 4.42), poor dietary diversity (AOR = 1.93; 95% CI: 1.03, 3.62), and using unprotected water for drinking (AOR = 1.68; 95% CI: 1.21, 2.94) were significant factors.

Conclusion

Among children aged 6–59 months, the level of stunting in the pastoral community was significantly high. The study found that stunting was associated with multiple nutritional and non-nutritional factors. To tackle stunting, inter-sectoral cooperation is needed by enhancing the clean water supply of the community, optimal breastfeeding practice, food diversity, and economic status.
Organizational practices promoting employees’ pro-environmental behaviors in a Visegrad Group country: How much does company ownership matter?
Authors: Piwowar-Sulej Katarzyna , Kołodziej Izabela
Published: February 2022

Although company ownership (local vs. foreign) has been used as a contingency variable that differentiates companies’ environmental activities and performance, the current understanding of these differences is fragmented. None of the previous studies examined the relationships between company ownership and a complex set of organizational practices which promote employees’ pro-environmental behaviors. The article fills the gap in previous research by analyzing the extent to which a total of 37 organizational practices are used. These practices are divided into technical (20 are related to environmental management) and “soft” (17 are related to HRM policies). For this study, both literature studies and a survey covering 199 companies located in Poland were used. In the theoretical part, the paper presents various typologies of factors that enhance employees’ green behavior, with the focus on organizational practices. There is also a review of studies on environmental sustainability which used company ownership as a variable. The results of the empirical research show that–although in foreign companies environmental issues are increasingly perceived as important or very important–many of the practices which are treated as crucial for developing employees’ eco-friendly behaviors are rarely used in both local and foreign companies. Moreover, company ownership was important in the context of using 88% of the “soft” practices and 50% of the technical practices discussed in the article. The article provides implications for policy and practice, as well as directions for further research.
Zinc protoporphyrin levels in COVID-19 are indicative of iron deficiency and potential predictor of disease severity
Authors: Kilercik Meltem , Ucal Yasemin , Serdar Muhittin , Serteser Mustafa , Ozpinar Aysel , Schweigert Florian J.
Published: February 2022

Background

Coronavirus disease (COVID-19) has a severe impact on all aspects of patient care. Among the numerous biomarkers of potential validity for diagnostic and clinical management of COVID-19 are biomarkers at the interface of iron metabolism and inflammation.

Methods

The follow-up study included 54 hospitalized patients with laboratory-confirmed COVID-19 with a moderate and severe/critical form of the disease. Iron deficiency specific biomarkers such as iron, ferritin, transferrin receptor, hepcidin, and zinc protoporphyrin (ZnPP) as well as relevant markers of inflammation were evaluated twice: in the first five days when the patient was admitted to the hospital and during five to 15 days; and their validity to diagnose iron deficiency was further assessed. The regression and Receiver Operating Characteristics (ROC) analyses were performed to evaluate the prognosis and determine the probability for predicting the severity of the disease in the first five days of COVID-19.

Results

Based on hemoglobin values, anemia was observed in 21 of 54 patients. Of all iron deficiency anemia-related markers, only ZnPP was significantly elevated (P<0.001) in the anemic group. When patients were grouped according to the severity of disease, slight differences in hemoglobin or other anemia-related parameters could be observed. However, the levels of ZnPP were significantly increased in the severely ill group of patients. The ratio of ZnPP to lymphocyte count (ZnPP/L) had a discrimination power stronger than the neutrophil to lymphocyte count ratio (N/L) to determine disease severity. Additionally, only two markers were independently associated with the severity of COVID-19 in logistic regression analysis; D-dimer (OR (5.606)(95% CI 1.019–30.867)) and ZnPP/L ratio (OR (74.313) (95% CI 1.081–5108.103)).

Conclusions

For the first time ZnPP in COVID-19 patients were reported in this study. Among all iron-related markers tested, ZnPP was the only one that was associated with anemia as based on hemoglobin. The increase in ZnPP might indicate that the underlying cause of anemia in COVID-19 patients is not only due to the inflammation but also of nutritional origin. Additionally, the ZnPP/L ratio might be a valid prognostic marker for the severity of COVID-19.
Magnetic resonance angiography derived predictors of progressive dilatation and surgery of the aortic root in Marfan syndrome
Authors: Weinrich Julius Matthias , Lenz Alexander , Schön Gerhard , Behzadi Cyrus , Molwitz Isabel , Henes Frank Oliver , Schoennagel Bjoern Philip , Adam Gerhard , von Kodolitsch Yskert , Bannas Peter
Published: February 2022

Background

To identify magnetic resonance (MR) angiography derived predictors of progressive dilatation and surgery of the aortic root in Marfan syndrome.

Material and methods

We retrospectively included 111 patients (32.7±16.5 years, range: 7–75 years) with a total of 446 MR angiographies. Aortic diameter growth rates of the entire thoracic aorta and Z-scores were estimated from annual diameter measurements. Aortic root shape was subdivided into three different types: (T0) normal; (T1) localized dilatation; (T2) generalized aortic root dilatation. Aortic diameter, Z-score, age, and aortic root shape at baseline were tested as predictors of aortic root dilatation using a multivariate logistic regression model.

Results

The highest aortic growth rate was observed at the level of the sinuses of Valsalva. Higher aortic root diameters and Z-scores at baseline predicted an increased growth of the aortic root (p = 0.003 and p<0.001). Young age (<30 years) was a predictor for the increase of Z-scores when compared to patients ≥30 years (p = 0.019). 25/111 patients (22.5%) had a T0 aortic root shape, 59/111 patients (53.2%) had a T1 aortic root shape, and 27/111 patients (24.3%) had a T2 aortic root shape. Aortic root shape did not predict further aortic growth (p>0.05). However, significantly more patients undergoing surgery had a generalized aortic dilatation (19/28, 76.9%) than a localized aortic root dilatation (9/28, 32.1%) (p = 0.001).

Conclusion

Larger baseline aortic root diameter and Z-score as well as young age predict solely progressive aortic root dilatation in Marfan patients. MR angiography derived type of aortic root shape does not predict aortic growth, but patients with generalized aortic root dilatation are referred more frequently for aortic surgery.
Unpredictability of the “when” influences prediction error processing of the “what” and “where”
Authors: Tsogli Vera , Jentschke Sebastian , Koelsch Stefan
Published: February 2022

The capability to establish accurate predictions is an integral part of learning. Whether predictions about different dimensions of a stimulus interact with each other, and whether such an interaction affects learning, has remained elusive. We conducted a statistical learning study with EEG (electroencephalography), where a stream of consecutive sound triplets was presented with deviants that were either: (a) statistical, depending on the triplet ending probability, (b) physical, due to a change in sound location or (c) double deviants, i.e. a combination of the two. We manipulated the predictability of stimulus-onset by using random stimulus-onset asynchronies. Temporal unpredictability due to random onsets reduced the neurophysiological responses to statistical and location deviants, as indexed by the statistical mismatch negativity (sMMN) and the location MMN. Our results demonstrate that the predictability of one stimulus attribute influences the processing of prediction error signals of other stimulus attributes, and thus also learning of those attributes.
Green returns to education: Does education affect pro-environmental attitudes and behaviors in China?
Authors: Wang Qi , Niu Geng , Gan Xu , Cai Qiaoling
Published: February 2022

Using microdata from the Chinese General Social Survey (CGSS 2010), this paper investigates whether there are green returns to education in China, where educational attainment promotes pro-environmental attitudes and behaviors. We establish causality by exploiting the exogenous variation induced by the implementation of the Compulsory Schooling Law (CSL) in China. We find evidence that educational attainment is associated with higher levels of pro-environmental attitudes and behaviors, and these estimates are robust to various robustness checks. Further analysis reveals that the acquisition of environmental knowledge is the channel that drives the effect of education on pro-environmental attitudes and behaviors. Finally, the effects of education are heterogeneous across individuals.
Quantifying volume and high-speed technical actions of professional soccer players using foot-mounted inertial measurement units
Authors: Lewis Glyn , Towlson Christopher , Roversi Pietro , Domogalla Chris , Herrington Lee , Barrett Steve
Published: February 2022

Aims

The aims of the study were two-fold: i) examine the validity and reliability of high-speed kicking actions using foot-mounted inertial measurement unit’s (IMU), ii) quantify soccer players within-microcycle and inter-positional differences in both the frequency and speed of technical actions.

Methods

During the in-season phase (25 weeks) of the UK domestic season, 21 professional soccer player ball releases, high-speed ball releases and ball release index were analysed. Pearson product-moment correlation coefficient and confidence intervals were used to determine the validity between the systems, whilst a general linear mixed model analysis approach was used to establish estimated marginal mean values for total ball releases, high-speed ball releases and ball release index.

Results

Good concurrent validity was observed for ball release velocity and high-speed kicks against a high-speed camera (r2- 0.96, CI 0.93–0.98). Ball releases, high-speed ball releases and ball release index all showed main effects for fixture proximity (p>0.001), playing positions (p>0.001) and across different training categories (p>0.001). The greatest high-speed ball releases were observed on a match-day (MD)+1 (17.6 ± 11.9; CI- 16.2 to 19) and MD-2 (16.8 ± 15; CI- 14.9 to 18.7), with MD+1 exhibiting the highest number of ball releases (161.1 ± 51.2; CI- 155.0 to 167.2) and ball release index (145.5 ± 45.2; CI- 140.1 to 150.9) across all fixture proximities. Possessions (0.3 ± 0.9; CI- 0.3 to 0.4) and small-sided games (1.4 ± 1.6; CI- 1.4 to 1.5), had the lowest values for high-speed ball releases with technical (6.1 ± 7.2; CI- 5.7 to 6.6) and tactical (10.0 ± 10.5; CI- 6.9 to 13.1) drills showing the largest high-speed ball releases.

Conclusions

The present study provides novel information regarding the quantification of technical actions of professional soccer players. Insights into absolute and relative frequency and intensity of releases in different drill types, provide practitioners with valuable information on technical outputs that can be manipulated during the process of planning training programmes to produce desired outcomes. Both volume and speed of ball release actions should be measured, when monitoring the technical actions in training according to fixture proximity, drill type and player position to permit enhanced training prescription.
Daily feeding rhythm linked to microbiome composition in two zooplankton species
Authors: Pfenning-Butterworth Alaina , Cooper Reilly O. , Cressler Clayton E.
Published: February 2022

Host-associated microbial communities are impacted by external and within-host factors, i.e., diet and feeding behavior. For organisms known to have a circadian rhythm in feeding behavior, microbiome composition is likely impacted by the different rates of microbe introduction and removal across a daily cycle, in addition to any diet-induced changes in microbial interactions. Here, we measured feeding behavior and used 16S rRNA sequencing to compare the microbial community across a diel cycle in two distantly related species of Daphnia, that differ in their life history traits, to assess how daily feeding patterns impact microbiome composition. We find that Daphnia species reared under similar laboratory conditions have significantly different microbial communities. Additionally, we reveal that Daphnia have daily differences in their microbial composition that correspond with feeding behavior, such that there is greater microbiome diversity at night during the host’s active feeding phase. These results highlight that zooplankton microbiomes are relatively distinct and are likely influenced by host phylogeny.
Volume estimation models for avocado fruit
Authors: Mokria Mulugeta , Gebrekirstos Aster , Said Hadia , Hadgu Kiros , Hagazi Niguse , Dubale Workneh , Bräuning Achim
Published: February 2022

Avocado (Persea americanaMill.) is an important horticultural crop and proved to be a very profitable commercial crop for both local consumption and export. The physical characteristics of fruits are an important factor to determine the quality of fruit produced. On the other hand, estimation of fruit volume is time-consuming and impractical under field conditions. Thus, this study was conducted to devise cultivar-specific and generalized allometric models to analytically and non-destructively determine avocado fruit volume of five wildly distributed avocado cultivars. A significant relationship (P≤ 0.01) was found between fruit diameter, length, and volume of each cultivar. Our best models (VM2 –for cultivar specific, and VM7-generalized model) has passed all the rigorous cross-validation and performance statistics tests and explained 94%, 92%, 87%, 93%, 94% and 93% of the variations in fruit volume of Ettinger, Fuerte, Hass, Nabal, Reed, and Multiple cultivars, respectively. Our finding revealed that in situations where measurements of volume would be inconvenient, or time-consuming, a reliable volume and yield estimation can be obtained using site- and cultivar-specific allometric equations. Allometric models could also play a significant role in improving data availability on avocado fruit physical appearance which is critical to assess the quality and taste of fresh products influencing the purchase decision of customers. Moreover, such information can also be used as a ripeness index to predict optimum harvest time important for planned marketing. More importantly, the models might assist horticulturists, agronomists, and physiologists to conduct further study on avocado production and productivity through agroforestry landuse system across Ethiopia.
The magnitude and effect of work-life imbalance on cognition and affective range among the non-western population: A study from Muscat
Authors: Al-Adawi Samir , Alameddine Mohamad , Al-Saadoon Muna , Al Balushi Amal A. , Chan Moon Fai , Bou-Karroum Karen , Al-Kindy Hamad , Al-Harthi Saud M.
Published: February 2022

The temporal relationship between work-life balance/imbalance, occupational burnout, and poor mental health outcomes have been widely explored. Little has been forthcoming on cognitive functioning among those with work-life imbalance. This study aimed to explore the rate of work-life imbalance and the variation in neuropsychological functioning. The relationship between affective ranges (anxiety and depressive symptoms) and work-life balance was also explored. The target population in this study are Omani nationals who were referred for psychometric evaluation. The study employs neuropsychology measures tapping into attention and concentration, learning and remembering, processing speed, and executive functioning. Subjective measures of cognitive decline and affective ranges were also explored. A total of 168 subjects (75.3% of the responders) were considered to be at a work-life imbalance. Multivariate analysis showed that demographic and neuropsychological variables were significant risk factors for work-life imbalance including age and the presence of anxiety disorder. Furthermore, participants indicating work-life imbalance were more likely to report cognitive decline on indices of attention, concentration, learning, and remembering. This study reveals that individuals with work-life imbalance might dent the integrity of cognition including attention and concentration, learning and remembering, executive functioning, and endorsed case-ness for anxiety.
Exploring non-physician care professionals’ roles in cancer multidisciplinary team meetings: A qualitative study
Authors: Horlait Melissa , De Regge Melissa , Baes Saskia , Eeckloo Kristof , Leys Mark
Published: February 2022

The growing complexity of cancer care necessitates collaboration among different professionals. This interprofessional collaboration improves cancer care delivery and outcomes. Treatment decision-making within the context of a multidisciplinaire team meeting (MDTMs) may be seen as a particular form of interprofessional collaboration. Various studies on cancer MDTMs highlight a pattern of suboptimal information sharing between attendants. To overcome the lack of non-medical, patient-based information, it might be recommended that non-physician care professionals play a key patient advocacy role within cancer MDTMs. This study aims to explore non-physician care professionals’ current and aspired role within cancer MDTMs. Additionally, the perceived hindering factors for these non-physician care professionals to fulfil their specific role are identified. The analysis focuses on nurses, specialist nurses, head nurses, psychologists, social workers, a head of social workers and data managers. The results show that non-physician care professionals play a limited role during case discussions in MDTMs. Neither do they actively participate in the decision-making process. Barriers perceived by non-physician care professionals are classified on two main levels: 1) team-related barriers (factors internally related to the team) and 2) external barriers (factors related to healthcare management and policy). A group of non-physician care professionals also belief that their information does not add value in the decision-making proces and as such, they underestimate their own role in MDTMs. To conclude, a change of culture is needed towards an interdisciplinary collaboration in which knowledge and expertise of different professions are equally assimilated into an integrated perspective to guarantee a true patient-centred approach for cancer MDTMs.
Human C2a and C6a iPSC lines and H9 ESC line have less efficient cardiomyogenesis than H1 ESC line: Beating enhances cardiac differentiation
Authors: Sepac Ana , Bosnjak Zeljko J. , Seiwerth Sven , Sikiric Suncana , Dzombeta Tihana Regovic , Kulic Ana , Karsaj Jelena Marunica , Sedlic Filip
Published: February 2022

Background: Human induced pluripotent stem cells (hiPSCs) need to be thoroughly characterized to exploit their potential advantages in various aspects of biomedicine. The aim of this study was to compare the efficiency of cardiomyogenesis of two hiPSCs and two human embryonic stem cell (hESC) lines by genetic living cardiomyocyte labeling. We also analyzed the influence of spontaneous beating on cardiac differentiation. Methods: H1 and H9 hESC lines and C2a and C6a hiPSC lines were induced into in vitro directed cardiac differentiation. Cardiomyogenesis was evaluated by the analysis of cell cluster beating, cardiac protein expression by immunocytochemistry, ability of cells to generate calcium transients, and cardiomyocyte quantification by the myosin light chain 2v-enhanced green fluorescent protein gene construct delivered with a lentiviral vector. Results: Differentiation of all cell lines yielded spontaneously beating cell clusters, indicating the presence of functional cardiomyocytes. After the cell dissociation, H1-hESC-derived cardiomyocytes exhibited spontaneous calcium transients, corresponding to autonomous electrical activity and displayed ability to transmit them between the cells. Differentiated hESC and hiPSC cells exhibited striated sarcomeres and expressed cardiac proteins sarcomeric α-actinin and cardiac troponin T. Cardiomyocytes were the most abundant in differentiated H1 hESC line (20% more than in other tested lines). In all stem cell lines, cardiomyocyte enrichment was greater in beating than in non-beating cell clusters, irrespective of cardiomyogenesis efficiency. Conclusion: Although C2a and C6a hiPSC and H9 hESC lines exhibited efficient cardiomyogenesis, H1 hESC line yielded the greatest cardiomyocyte enrichment of all tested lines. Beating of cell clusters promotes cardiomyogenesis in tested hESCs and hiPSCs.
In ovo manipulation of Nile crocodile embryos: egg windowing and potential dental research applications
Authors: Truter J. Christoff , Myburgh Jan G.
Published: February 2022

Crocodilians exhibit continuous tooth replacement (i.e., polyphyodonty) and have been identified as suitable models for tooth regeneration research due to the similarity in dental cavity and tooth anatomy between these creatures and humans. Various studies reporting in ovo bird embryo manipulation exist, but such reports for reptiles are virtually non-existent. Egg windowing enables direct access to oviparous vertebrate embryos and is therefore an important component of in ovo embryo manipulation experiments. The aim of the present study was to window Nile crocodile, Crocodylus niloticus eggs and assess the potential of direct manipulations, targeting the pharyngeal region where the maxilla and mandible originates. Crocodylus niloticus eggs were successfully windowed, and a limited number of individuals survived the entire gestation period. The 1st trimester of gestation was the most sensitive, and 96.78% of the mortalities occurred within this period. Our data indicate the suitable window for embryo manipulation targeting the mandibular arch and maxillary process, without a risk of damaging the chorioallantoic membrane (CAM) (which may be fatal), was between day six and eight after laying for embryos incubated at 31°C. This data will be of use for future embryo-based experiments related to jaw and tooth development in crocodiles as well as human tooth regeneration research.
Molecular prevalence of Dirofilaria immitis and Wolbachia infections in pet and semi-domesticated cats in Bangkok, Thailand
Authors: Thengchaisri Naris , Inpankaew Tawin , Arthitwong Surapong , Steiner Jörg M. , Sattasathuchana Panpicha
Published: February 2022

Background and Aim: Although cats are not natural hosts for heartworm infections (Dirofilaria immitis), evidence suggests that feline heartworm disease can be detrimental because of a severe inflammatory response. Recent studies have found that infection with bacteria of the genus Wolbachia is the principal cause of acute inflammatory filaria disease; nonetheless, the prevalence of cats naturally infected with heartworms and Wolbachia remains unclear. This study aimed to estimate the prevalence and current distribution of feline heartworm disease and its association with Wolbachia infection in pet and semi-domesticated cats in Bangkok, Thailand.

Materials and Methods: A total of 260 cats (130 pet cats and 130 semi-domesticated cats) were enrolled in this study. Blood samples were placed into ethylenediaminetetraacetic acid tubes for hematological analysis and DNA extraction. A polymerase chain reaction (PCR) was performed to analyze samples for the presence of D. immitis and Wolbachia infections.

Results: The prevalence (95% confidence interval [CI]) of D. immitis infection in pet, semi-domesticated, and all cats were 3.9% (1.3-8.8%), 27.7% (20.2-36.2%), and 19.6% (15.0-25.0%), respectively. The prevalence (95% CI) of Wolbachia infection in pet, semi-domesticated, and all cats were 18.5% (12.2-26.2%), 31.5% (23.7-40.3%), and 25.0% (19.9-30.7%), respectively. The prevalence of D. immitis and Wolbachia infections in semi-domesticated cats was significantly higher than in pet cats (p=0.002 and p=0.022, respectively). There was a significant association between D. immitis and Wolbachia infections (p<0.001). There was also a significant association between D. immitis infection and the presence of eosinophilia (p<0.045).

Conclusion: From the PCR analysis, it can be concluded that semi-domesticated cats were at higher risk for D. immitis infection than pet cats. There was a significant association between positive D. immitis infection and positive Wolbachia infection. Combinations of anthelmintic and antimicrobial therapy should be considered in heartworm-positive cats.
Paradigmaváltás(ok) a magyarországi turisztikai desztinációk fejlesztésében és menedzselésében
Authors: Aubert Antal , Barcza Attilla , Gonda Tibor , Horváth Zoltán , Pálfi Andrea
Published: February 2022

Tanulmányunkban a hazai turizmus irányítás változó rendszerével foglalkozunk, amelynek elmúlt csaknem tíz évében desztinációs szinten tagadhatatlanul meghatározó szereplői voltak a turisztikai desztináció menedzsment (TDM) szervezetek. Munkánk során áttekintettük a TDM szervezetek létrehozására, működésük finanszírozá­sára kiírt pályázatokat, hiszen ezekből kirajzolódtak a hazai TDM rendszer sajátosságai. Egy kérdőíves felmérés keretein belül a TDM rendszer nehézségeire és a rendszerben rejlő veszélyekre kívánunk rávilágítani.

2016-ban, a Magyar Turisztikai Ügynökség megalakulásával új fejezete kezdődött a hazai turizmus ter­vezésnek és menedzselésnek, amelynek alapjait a Nemzeti Turizmusfejlesztési Stratégia 2030 c. dokumentum alapján tekintettünk át. A kijelölt kiemelt turisztikai fejlesztési térségek, mint új térkategóriák, meghatározó egységei lesznek az elkövetkezendő tervezési és megvalósítási időszaknak, amely alapjaiban határozza meg az egyes turisztikai célterületek jövőjét. Tanulmányunk célja, hogy a témában átfogó képet nyújtsunk a turiszti­kai szektor gyakorlati és elméleti szakemberei számára az elmúlt időszakot áttekintve, illetve az elkövetkezendő időszak terveit vázolva, amelyek természetesen nemcsak a turizmus gazdaságra hatnak, hanem éppúgy meg­határozóak a desztinációk területi megjelenése és tervezése nyomán, hovatovább a későbbi területi márkázás és márka identitás kialakításának vonatkozásában.