bluuebunny/crossref_metadata_2025 huggingface dataset:
Central Sensitization in Spondyloarthritis: The Crossroads between
Disease Activity, Health-related Quality of Life and Fibromyalgia
Authors: Aicha Ben Tekaya , Ines Cherif , Olfa Saidane , Selma Bouden , Leila Rouached , Rawdha Tekaya , Ines Mahmoud , Leila Abdelmoula
Published: March 2023

Objective:

To assess central sensitization in young patients with spondyloarthritis (SpA) and to study the associated factors with higher central sensitization scores.

Methods:

This was a cross-sectional study including patients with SpA (ASAS criteria) aged less than 50 years. For all patients, we collected the sociodemographic and disease characteristics data. Central sensitization was assessed using a validated tool: The Central Sensitization inventory (CSI). Pain status, fibromyalgia, quality of life, anxiety and depression were screened by the Brief pain in-ventory, the Fibromyalgia rapid screening tool (FiRST), the ASQoL, and the Hospital anxiety and depression scale (HAD) anxiety and depression. Univariable and multivariable linear regression analyses were performed to achieve our objective

Results:

Seventy-two patients were enrolled (65,2% males). The median age was 39 (28,25-46) years. Median BASDAI and ASDAS-CRP scores were 3 (2.1 - 4.7) and 2.7 (1.9 - 3.48), respective-ly. The median value of the CSI score was 15 (6,25-33,75); a CSI≥40 was noted in 15.3% of pa-tients. Depression, anxiety scores, fibromyalgia and impaired QoL were screened in 11%, 9,7%, 9,7%, and 44,4%, respectively. CSI≥40 was positively correlated with ASQoL, FiRST, HAD anxie-ty, HAD depression and the 5 categories of pain interference (mood, regular work, relationships, sleep and enjoyment of life). Multivariate analysis identified a predictive model which included the combination of FiRST, BASDAI and ASQoL. First was the strongest predictive factor of a higher central sensitization.

Conclusion:

CS is frequent among SpA patients and should be looked for in order to improve QoL.
The Readability of Language: Observing the Non-Linguistic and Linguistic Features in the Communication of a Child with Congenital Deafblindness
Authors: Braad Annelies
Published: March 2023

Children with congenital deafblindness (CDB) have, similar as deaf and hearing children, an innate ability to acquire a language. It is known to be a challenge for children with CDB to acquire a first language. Most children with CDB do not learn to speak or sign and remain at a pre-linguistic level of language development. Observing non-linguistic and linguistic features is essential for pre-linguistic and early linguistic language development. This study used a systematic observation instrument to observe the non-linguistic and linguistic features of a child with CDB. The case study resulted in a qualitative analysis of communicative expressions and signs made by the child with CDB. BET's and gestures were expressed consistently and correctly in the context of the communication. The linguistic features of the signs expressed by the child did not match the features used in the conventional signs. Also, the child produced different phonological forms of one particular sign, making the signs of the child inconsistent. We discussed that inconsistent signs can lead to difficulty with the signs by the communication partner. Difficulty with readability of signs of the child by the communication partner may negatively influence the language development of the child. Different possible causes of the incorrect and inconsistent signs of the child were discussed, such as the inability of the child with CDB to access the linguistic features of the communication of the communication partner. Recommendations were given to support the language acquisition of children with CDB. Also, recommendations were given for further research.
Coining Tactile Signs: A Guided Experience of Tactile Communication for People with Acquired Deafblindness and their Communication Partners
Authors: Algorta Mariana Silva
Published: March 2023

Introduction: When hearing and vision are affected simultaneously, communication can be challenging (Nordic Welfare Centre, 2016). However, undertaking a bodily – tactile modality of communication can benefit the interactions for people with acquired deafblindness and their partners (Lahtinen, 2008). This research aimed to understand the process of creating tactile communication. It focused on analysing the process of coining tactile signs for specific objects. Method: A qualitative and descriptive case study was conducted, utilizing video-analysis and questionnaires. An intervention was based on a learning guide and inspired by the project Landscape of Touch (Tactile Communication Group DbI, 2012). Different activities of tactile communication, progressive in complexity, led the participants to a final experience of coining (the creation of) their own tactile signs. Results: The results showed three blended stages in the coining process, tactile exploration, information selection and negotiation of meaning. The coined signs were compared with their visual pair of NZSL [New Zealand Sign Language] finding several similarities in their components. This research had an expanding effect on the participant’s perspective of tactile communication and the possibility of integrating it to their daily life. Conclusion and Discussion: Further research on sign coining and tactile elements in the communication, including individual experiences, is essential for developing good practices for educators and support service providers in this field. It is recommended to use video analysis as a tool to observe the details in the handmovements. Some limitations in this study were the application in a case study, therefore no generalisations can be made, and the access to technology limited the possibilities for other possible participants.
Character Education Integration in Distance Learning System Based on Multiple Intelligence Theory: Case Study at SMKN 2 Malang
Authors: Herlambang Admaja Dwi , Rahmawati Qonita , Wardhono Wibisono Sukmo
Published: March 2023

This study aims to determine how the strategies carried out by Public Vocational High Schools in Malang City, Indonesia, implement character education in the distance learning system. This research occurred at the 2nd  PublicVocational High School (SMKN 2 Malang), Computer and Network Engineering Department. The design of this research is an interactive qualitative analysis model, i.e., reduction, data presentation, and deduction. Data collection techniques are in-depth interviews, observation, and documentation for six months. Data documentation consists of diagnostic tests, Learning Management System (LMS) screenshots, and discipline time records during distance learning. This study shows that from knowledge aspect, teachers can understand students' character well so that the application of multiple intelligence strategies by utilizing diagnostic tests and LMS can be realized. However, the implementation of character education often experiences problems or lacks student technical support, so its implementation is carried out consistently by incorporating character values in every learning activity. This study recommends that observation activities be carried out when learning activities need to be optimized with synchronous learning activities.
Social construction of law enforcement for sexual violence against women in Aceh Utara
Authors: Zulkifli Zulkifli , Rahman Arief , Martina Martina , Mumtiza Rizka , Risma Mauliza
Published: March 2023

The level and types of sexual violence crimes in Indonesia are increasing and worrying the public. Law enforcement efforts to overcome criminal acts of sexual violence are increasingly being implemented. This study aims to examine the social construction of law enforcement against the crime of sexual violence against women in Aceh Utara. Respondents in the study amounted to 21 people who were selected with accidental sampling. The types of data in the form of primary data and secondary data were analyzed descriptively qualitatively. The results of the study explain that the legal basis used in the law enforcement process of sexual violence against women in Aceh Utara is Aceh Qanun Number 6 of 2014 concerning Inayat Law. Criminal charges for perpetrators of sexual violence in Aceh are whipping, fines, and imprisonment. It was found that the criminal sanctions contained in the qanun jinayat were lighter than the national law. For this reason, it is necessary to revise the qanun to provide a more severe deterrent effect on perpetrators, protect witnesses and victims with adopting developments in national laws related to sexual violence while still referring to the Aceh's Islamic characteristics.
The application of the right to freedom of expression in demonstration based on principles of a democratic state
Authors: Sofwan Edi , Sopiyana Muhammad , Fathurrahman Ali Masykur
Published: March 2023

Expressing opinions in demonstration is a right that has been guaranteed in the constitution and law. The arrangement is written in the 1945 Constitution of the Republic of Indonesia Article 28E paragraph (3) and Law Number 9 of 1998 concerning the freedom to express opinion in public. A democratic country has a great respect for differences of opinion manifested in the form of demonstration. However, the freedom of demonstration is in the form of responsible freedom regulated in Article 6 of Law No. 9 of 1998. In this demonstration, the actions must respect the rights of others, so that no one is harmed by the demonstration. If someone is harmed, they must prioritize the principles of justice in accordance with applicable law. This study was conducted with a qualitative method approach, namely by using the type of normative research, by conducting a study of legislation (Statute approach). This study resulted that the demonstration arrangements regulated in the law must be respected by all parties, where the principle of legal protection is attached to demonstration participants and security forces to respect each other's democratic values in Indonesia. Furthermore, on the principle of right to freedom of expression in a democratic country, all citizens must have the same rights in any form of expression. If there is a party who is harmed, it must be resolved according to the applicable law, so that the Indonesian guarantee legal certainty from irresponsible parties to uphold democratic values, as well as freedom of opinion.
The Pragmatic Function of Speech for Elementary Students: Indonesian Teaching in Australia
Authors: Wibowo Setiawan Edi , Cholomeischi Aurora Adina , Colomeischi Tudor , Schulze Kordula
Published: March 2023

This study aimed to describe the pragmatic function of an Indonesian language teaching in Australia and describe the speech act strategies used by foreign teachers to teach Indonesian in Australia. It employs a descriptive qualitative method with a case study approach to the pragmatic function construction in the classroom context. The data are negatively-constructed speeches of a teacher and students who join an Indonesia language learning program, The Apec Lesson Study Project, in Australia. Data are collected through documentation with extended techniques, listening, and recording. Meanwhile, the data are analyzed by using a method of padan pragmatics. The research results show that the pragmatic functions in Indonesian language teaching in Australia can be estimated into various categories and subcategories of speech acts: (1) combinative speech act, manifested into sub-speech acts asking-praising; and (2) directive speech act, manifested into sub-speech acts asking. These findings show how materials, methods, techniques are combined with speech constructions that are appropriate to the student's level. Meanwhile, the speech act strategy used by foreign teachers is a direct literal speech act strategy.
Определение растворимости кобальта в монокристаллическом кремнии методом нейтронно-активационного анализа
Authors: Ташметов М.Ю. , Махкамов Ш. , Тиллаев T.С. , Эрдонов М.Н. , Холмедов Х.М.
Published: March 2023

Abstract.
The possibility of instrumental neutron activation analysis is revealed for determining the solubility of cobalt in single-crystal silicon. It was shown that in n-Si in the diffusion temperature range of 1000  1250 0С the total solubility of the 60Co impurity varies within the concentration range of 2.8 ∙ 1014  9 ∙ 1015 cm-3, and the electrically active concentration grows from 1013 to 3 ∙ 1014 cm-3. In order to reduce the error in determining the concentration of 60Co in doped Si samples, it is suggested to use the parent stable isotope rather than the daughter cobalt radionuclide.
Фазовые состояния твердого раствора (1-x)PbFe-=SUB=-0.5-=/SUB=-Nb-=SUB=-0.5-=/SUB=-O-=SUB=-3-=/SUB=--xPbTiO-=SUB=-3-=/SUB=-. Описание на основе многоминимумных моделей
Authors: Ивлиев М.П. , Раевская С.И. , Титов В.В. , Раевский И.П. , Малицкая М.А.
Published: March 2023

Based on the composition of two multiminimum models, a statistical model has been developed on the basis of which the formation of tetragonal and monoclinic ferroelectric phases in a solid solution (1-x)PbFe0.5Nb0.5O3-xPbTiO3 has been investigated and described. By selecting the parameters of the model, it was possible to reproduce the diagram T(x) of this solid solution. The peculiarity of the diagram is that when approaching the concentration of x~0.1, the temperatures of the phase transitions between the tetragonal and monoclinic phases decrease sharply, turning to zero. It is shown that the disappearance of the monoclinic phase is due to the specifics of the statistical properties of the eight-minimum model describing the subsystem of octahedra with eight minima. The features of the thermodynamic properties of a solid solution in the vicinity of the morphotropic boundary between the tetragonal and monoclinic phases are also investigated
Поверхностный Ti-Ni-Ta-сплав, синтезированный на TiNi-подложке электронно-пучковым способом: структура и физико-механические свойства
Authors: Дьяченко Ф.А. , Семин В.О. , Остапенко М.Г. , Мейснер Л.Л.
Published: March 2023

The structure and physical-mechanical properties of Ti-Ni-Ta-based surface alloy synthesized on the NiTi-substrate through additive thin-film electron-beam method have been studied. The synthesis of the surface alloy was carried out by 30-fold alternation of operations of deposition of a dopant film (Ti60Ta40 (at.%), ~50 nm thick) and liquid-phase mixing of the film/substrate using a pulsed low-energy high-current electron beam. It was found that Ti-Ni-Ta-based surface alloy, whose thickness is ~1.8 μm, has an amorphous structure. It has been established that the surface alloy has ~2 and ~1.5 times higher values of microhardness HOP and elastic modulus EOP compared to the initial NiTi-substrate, but parameter of plasticity δh and shape recovery ratio η close to the substrate. It is shown that the nature of the change in physical-mechanical properties in Ti-Ni-Ta-based surface alloy and the transition zone depends on the number and thickness of the sublayers, as well as on the structural states of the phases in the sublayers. The evaluation of the mechanical compatibility of the surface alloy with the NiTi-substrate is given.
Особенности спектров комбинационного рассеяния света в области линии 2100 cm-=SUP=--1-=/SUP=- углеродными образованиями в тонких градиентных пленках золота
Authors: Компан М.Е. , Коньков О.И. , Никитин С.Е. , Малышкин В.Г.
Published: March 2023

Raman scattering spectra of linear carbon chains (carbines) localized in thin gold films of variable thickness are investigated. It is shown that the integral line is inhomogeneous, and separate components are identified, the intensity of which depends in a non-trivial way on the thickness of the film. Qualitative explanations of the detected effects are proposed.
Влияние немагнитного беспорядка на фазовые переходы первого рода
Authors: Бабаев А.Б. , Муртазаев А.К.
Published: March 2023

Using the Monte Carlo method, weakly dilute magnetic systems described
by two-dimensional five-component Potts model, which in the pure state undergoes a phase transition first order. Numerical studies have revealed that an insignificant quenched disorder, realized in the form of non-magnetic impurities, can change the order of phase transition in magnetic systems described by the two-dimensional five-component Potts model on a square lattice, for which a phase transition of the first order is observed in a homogeneous state. It is shown that such a phase change the transition is due to the fact that non-magnetic disorder prevents the coexistence of local phases characteristic of a phase transition of the first order at T = Tl .
Полученные плазменно-химическим осаждением a-C : ND покрытия: взаимосвязь эмиссионных свойств и фазового состава
Authors: Завидовский И.А. , Стрелецкий О.А. , Татаринцев А.А. , Миннебаев К.Ф. , Хайдаров А.А.
Published: March 2023

The coatings comprised of the nanodiamond-based and amorphous-carbon-based phases (a-C:ND coatings) are investigated. The a-C:ND coatings were synthesized by chemical vapor deposition in the arc discharge plasma (by plasma chemical deposition) at various concentrations of Ar/H2/CH4. Raman spectroscopy showed that, apart from the diamond substructure, studied coatings contain amorphous-carbon-based and polyene-based phases, while diamond phase is passivated by hydrogen to different degrees. The interplay between the deposition parameters and materials' structure is analysed. It was shown that the ordering of the amorphous substructure and the formation of the phase boundaries affect the electron transport and secondary electron emission properties. The subject of the investigation of the true secondary electron spectra for the analysis of the nanostructured carbon materials is analysed. It was shown that the change of the polyene fraction in the structure of the samples leads to the variation of the ratio of field emission and thermionic emission. The influence of the structure and phase composition of the samples on their electron emission properties is investigated. In particular, their effect on the turn on-field, which value varied in the 9-18 V/μm range for the studied samples, is analysed.
Морфология поверхности и структурные свойства кристаллов GaTe после ионно-плазменной обработки
Authors: Зимин С.П. , Амиров И.И. , Тиванов М.С. , Колесников Н.Н. , Королик О.В. , Ляшенко Л.С. , Жигулин Д.В. , Мазалецкий Л.А. , Васильев С.В. , Савенко О.B.
Published: March 2023

The effect of ion-plasma treatment on the physical properties of the surface of GaTe crystals is investigated. Gallium telluride crystals were grown by vertical zone melting under the pressure of an inert argon gas of 10.0 MPa at a temperature of 1000 °C and a zone displacement velocity of 9 mm/hr. The treatment was carried out in argon plasma in a high-density low-pressure radio frequency (RF) inductively coupled plasma reactor at an argon ion energy of 100-200 eV for 15-120 s. Using scanning electron microscopy methods, it was shown that the formation of nano- and submicron structures of various architectures (nanohillocks, nanocones, droplet structures) occurred on the surface during processing. It is shown that the sputtering processes are accompanied by enrichment of the near-surface layer with metal atoms and a decrease in oxygen content. The formation of nano- and submicron gallium droplets on the surface has been proved by X-ray diffractometry. The analysis of the raman scattering spectra showed a decrease in the oxide phases of tellurium after plasma treatment. It is established that modification of the GaTe surface leads to suppression of specular optical reflection in the range of 0.4-6.2 eV.
Boletín Agroclimático Regional: mesa técnica agroclimática de Tolima octubre 2022
Authors:   Ministerio de Agricultura y Desarrollo Rural, Bogotá (Colombia),   Organización de las Naciones Unidas para la Alimentación y la Agricultura, Bogotá (Colombia),   Instituto de Hidrología, Meteorología y Estudios Ambientales, Bogotá (Colombia)
Published: March 2023

La Mesa Técnica Agroclimática ( de Tolima, es un espacio de diálogo y análisis entre actores locales, regionales y nacionales, que busca comprender el posible comportamiento del clima Se realizó esta reunión de carácter presencial donde se presentó la perspectiva climática para el trimestre octubre, noviembre y diciembre de 2022 para el departamento Con base en esta información, se debatieron los posibles impactos y recomendaciones para el sector agropecuario de la región La información generada se ha recopilado en el presente Boletín Agroclimático para la edición correspondiente al mes de octubre de 2022 a cargo de FAO y FEDEARROZ y se presenta por cultivo o sector productivo.
Boletín Agroclimático Nacional No.90
Authors:   Ministerio de Agricultura y Desarrollo Rural, Bogotá (Colombia),   Organización de las Naciones Unidas para la Alimentación y la Agricultura, Bogotá (Colombia),   Instituto de Hidrología, Meteorología y Estudios Ambientales, Bogotá (Colombia)
Published: March 2023

El Boletín Agroclimático Nacional es elaborado por la Mesa Técnica Agroclimática Nacional, liderada por el Ministerio de Agricultura y Desarrollo Rural-MADR, en alianza con la Organización de la Naciones Unidas para la Alimentación y la Agricultura-FAO y el Instituto de Hidrología, Meteorología y Estudios Ambientales-IDEAM y el apoyo de gremios del sector agropecuario, la academia, Secretarías de Agricultura, entre otros actores del orden nacional y local. Este documento contiene el análisis del comportamiento del clima en diferentes regiones del país y brinda recomendaciones para una mejor proyección de las actividades agrícolas y pecuarias.
Boletín Agroclimático Regional: mesa técnica agroclimática de Santander mayo 2022
Authors:   Ministerio de Agricultura y Desarrollo Rural, Bogotá (Colombia),   Organización de las Naciones Unidas para la Alimentación y la Agricultura, Bogotá (Colombia),   Instituto de Hidrología, Meteorología y Estudios Ambientales, Bogotá (Colombia)
Published: March 2023

Con base en la información de los diferentes centros meteorológicos consultados, más la información local y los análisis desarrollados por parte del equipo de FENALCE-FNL, es de resaltar que, para el mes de mayo de 2022 el comportamiento de las lluvias estará por encima de los promedios en el sur del departamento, mientras la zona norte con lluvias entre lo climatológico y por debajo de los promedios siendo uno de los principales factores la primera temporada de lluvias, el continuo aporte de humedad desde el Océano Pacífico y la apertura de la temporada de huracanes en el cual las ondas tropicales empezaran a aportar humedad y lluvias en el país . Es de resaltar que en algunos casos las lluvias pueden presentar características fuertes por la energía almacenada en la atmosfera.
Using the New “Life’s Essential 8” Metrics to Evaluate Trends in Cardiovascular Health Among US Adults From 2005 to 2018: Analysis of Serial Cross-sectional Studies
Authors: Li Cheng , Li Yanzhi , Zhao Min , Zhang Cheng , Bovet Pascal , Xi Bo
Published: March 2023

Background

The recently published “Life’s Essential 8” (LE8) by the American Heart Association has overcome some limitations in evaluating cardiovascular health (CVH) in the previous “Life’s Simple 7.”

Objective

We aimed to examine the secular trends in CVH, as assessed by the LE8, in US adults from 2005 to 2018.

Methods

Using cross-sectional data from the National Health and Nutrition Examination Survey between 2005-2006 and 2017-2018, we calculated the age-standardized mean scores of overall CVH and each of the LE8 components, where a higher score (range 0-100 points) means a better health status. A total of 21,667 adults aged 20-79 years were included in this analysis.

Results

The overall CVH did not significantly change between 2005-2006 and 2017-2018 (65.5, 95% CI 63.9-67.1 to 65.0, 95% CI 62.8-67.1; P=.82). The individual metrics did not significantly change for diet (41.0, 95% CI 38.0-43.9 to 41.5, 95% CI 36.5-46.6; P=.94), physical activity (57.5, 95% CI 53.0-61.9 to 53.0, 95% CI 48.7-57.3; P=.26), and blood pressure (68.4, 95% CI 65.2-71.5 to 68.6, 95% CI 65.3-71.9, P=.35), improved for nicotine exposure (64.7, 95% CI 61.1-68.4 to 71.9, 95% CI 67.7-76.2; P<.001), sleep health (83.7, 95% CI 81.6-85.7 to 84.1, 95% CI 81.2-87.1; P=.006), and blood lipids (61.6, 95% CI 59.1-64.0 to 67.0, 95% CI 63.5-70.4; P<.001), and worsened for BMI (63.4, 95% CI 59.7-67.1 to 56.2, 95% CI 52.5-59.9; P<.001) and blood glucose (83.9, 95% CI 82.4-85.4 to 77.4, 95% CI 74.5-80.3; P<.001).

Conclusions

According to the LE8, the overall CVH did not change among US adults from 2005 to 2018, as well as 3 components (diet, physical activity, and blood pressure). Other metrics such as nicotine exposure, blood lipids, and sleep health improved, while BMI and blood glucose deteriorated over time.
An Evidence-Based Serious Game App for Public Education on Antibiotic Use and Antimicrobial Resistance: Protocol of a Randomized Controlled Trial
Authors: Huang Zhilian , Tang Wern Ee , Guo Huiling , Natarajan Karthiga , Lee Tau Hong , Yeo Tsin Wen , Chow Angela
Published: March 2023

Background

The misuse and overuse of antibiotics contribute to the acceleration of antimicrobial resistance (AMR), but public knowledge on appropriate antibiotic use and AMR remained low despite ongoing health promotion efforts. App gamification has gained traction in recent years for health promotion and to affect change in health behaviors. Hence, we developed an evidence-based serious game app “SteWARdS Antibiotic Defence” to educate the public on appropriate antibiotic use and AMR and address knowledge gaps.

Objective

We aim to evaluate the effectiveness of the “SteWARdS Antibiotic Defence” app in improving the knowledge of, attitude toward, and perception (KAP) of appropriate antibiotic use and AMR among the public. The primary objective is to assess the changes in KAP of antibiotic use and AMR in our participants, while the secondary objectives are to assess the extent of user engagement with the app and the level of user satisfaction in using the app.

Methods

Our study is a parallel 2-armed randomized controlled trial with a 1:1 allocation. We plan to recruit 400 participants (patients or their caregivers) aged 18-65 years from government-funded primary care clinics in Singapore. Participants are randomized in blocks of 4 and into the intervention or control group. Participants in the intervention group are required to download the “SteWARdS Antibiotic Defence” app on their smartphones and complete a game quest within 2 weeks. Users will learn about appropriate antibiotic use and effective methods to recover from uncomplicated upper respiratory tract infections by interacting with the nonplayer characters and playing 3 minigames in the app. The control group will not receive any intervention.

Results

The primary study outcome is the change in participants’ KAP toward antibiotic use and AMR 6-10 weeks post intervention or 6-10 weeks from baseline for the control group (web-based survey). We will also assess the knowledge level of participants immediately after the participant completes the game quest (in the app). The secondary study outcomes are the user engagement level (tracked by the app) and satisfaction level of playing the game (via the immediate postgame survey). The satisfaction survey will also collect participants’ feedback on the game app.

Conclusions

Our proposed study provides a unique opportunity to assess the effectiveness of a serious game app in public health education. We anticipate possible ceiling effects and selection bias in our study and have planned to perform subgroup analyses to adjust for confounding factors. The app intervention will benefit a larger population if it is proven to be effective and acceptable to users.

Trial Registration

ClinicalTrials.gov NCT05445414; https://clinicaltrials.gov/ct2/show/NCT05445414

International Registered Report Identifier (IRRID)

DERR1-10.2196/45833
Machine Learning Approaches for Predicting Psoriatic Arthritis Risk Using Electronic Medical Records: Population-Based Study (Preprint)
Authors: Lee Leon Tsung-Ju , Yang Hsuan-Chia , Nguyen Phung Anh , Muhtar Muhammad Solihuddin , Li Yu-Chuan Jack
Published: March 2023

BACKGROUND

Psoriasis (PsO) is a chronic, systemic, immune-mediated disease with multiorgan involvement. Psoriatic arthritis (PsA) is an inflammatory arthritis that is present in 6%-42% of patients with PsO. Approximately 15% of patients with PsO have undiagnosed PsA. Predicting patients with a risk of PsA is crucial for providing them with early examination and treatment that can prevent irreversible disease progression and function loss.

OBJECTIVE

The aim of this study was to develop and validate a prediction model for PsA based on chronological large-scale and multidimensional electronic medical records using a machine learning algorithm.

METHODS

This case-control study used Taiwan’s National Health Insurance Research Database from January 1, 1999, to December 31, 2013. The original data set was split into training and holdout data sets in an 80:20 ratio. A convolutional neural network was used to develop a prediction model. This model used 2.5-year diagnostic and medical records (inpatient and outpatient) with temporal-sequential information to predict the risk of PsA for a given patient within the next 6 months. The model was developed and cross-validated using the training data and was tested using the holdout data. An occlusion sensitivity analysis was performed to identify the important features of the model.

RESULTS

The prediction model included a total of 443 patients with PsA with earlier diagnosis of PsO and 1772 patients with PsO without PsA for the control group. The 6-month PsA risk prediction model that uses sequential diagnostic and drug prescription information as a temporal phenomic map yielded an area under the receiver operating characteristic curve of 0.70 (95% CI 0.559-0.833), a mean sensitivity of 0.80 (SD 0.11), a mean specificity of 0.60 (SD 0.04), and a mean negative predictive value of 0.93 (SD 0.04).

CONCLUSIONS

The findings of this study suggest that the risk prediction model can identify patients with PsO at a high risk of PsA. This model may help health care professionals to prioritize treatment for target high-risk populations and prevent irreversible disease progression and functional loss.
User-Centered Design and Evaluation of Clinical Decision Support to Improve Early Peanut Introduction: Formative Study (Preprint)
Authors: Nguyen Thinh Hoang , Cunha Priscila Pereira , Rowland Annabelle Friedman , Orenstein Evan , Lee Tricia , Kandaswamy Swaminathan
Published: March 2023

BACKGROUND

Peanut allergy has recently become more prevalent. Peanut introduction recommendations have evolved from suggesting peanut avoidance until the age of 3 years to more recent guidelines encouraging early peanut introduction after the Learning Early about Peanut Allergy (LEAP) study in 2015. Guideline adherence is poor, leading to missed care opportunities.

OBJECTIVE

In this study, we aimed to develop a user-centered clinical decision support (CDS) tool to improve implementation of the most recent early peanut introduction guidelines in the primary care clinic setting.

METHODS

We edited the note template of the well-child check (WCC) visits at ages 4 and 6 months with CDS prompts and point-of-care education. Formative and summative usability testing were completed with pediatric residents in a simulated electronic health record (EHR). We estimated task completion rates and perceived usefulness of the CDS in summative testing, comparing a test EHR with and without the CDS.

RESULTS

Formative usability testing with the residents provided qualitative data that led to improvements in the build for both the 4-month and 6-month WCC note templates. During summative usability testing, the CDS tool significantly improved discussion of early peanut introduction at the 4-month WCC visit compared to scenarios without the CDS tool (9/15, 60% with CDS and 0/15, 0% without CDS). All providers except one at the 4-month WCC scenario gave at least an adequate score for the ease of use of the CDS tool for the history of present illness and assessment and plan sections. During the summative usability testing with the 6-month WCC new build note template, providers more commonly provided comprehensive care once obtaining a patient history concerning for an immunoglobulin E–mediated peanut reaction by placing a referral to allergy/immunology (P=.48), prescribing an epinephrine auto-injector (P=.07), instructing on how to avoid peanut products (P<.001), and providing an emergency treatment plan (P=.003) with CDS guidance. All providers gave at least an adequate score for ease of use of the CDS tool in the after-visit summary.

CONCLUSIONS

User-centered CDS improved application of early peanut introduction recommendations and comprehensive care for patients who have symptoms concerning for peanut allergy in a simulation.
A Proposal of a simulation-optimization methodology for allocation of agencies with human resources on hexagonal tessellation
Authors: Rios-Esparza G A , Segura-Pérez E
Published: March 2023

The human resource assignment usually considers the search, qualification, selection, and allocation of human resources commonly based on their experience and professional development into different areas of a company. Rarely, the residence location and other characteristics of the personnel are considered.This paper takes a real case allocation problem from a public university social service program in Mexico City where the assignment process is restarted every six months. The lack of consideration of the personnel physical and functional attributes, led to an inefficient allocation process, increasing desertion of the program. To solve this problem, we propose a new methodology built on hexagonal tessellation capable of allocating personnel based on distance, schedules, and skills, which is later improved using simulation, reducing total travel distance in 585 km, improving matching schedules in 26%, matching skills in 37% and reduced the time dedicated to the allocation process from 5 days to 90 minutes.
Design and Fabrication of Plastic Cleaning and Drying Machine for Eco-Bricks
Authors: Bawane Prof. S. G. , Shambharkar Archies , Sonwane Mukesh
Published: March 2023

Abstract: In this project we try to overcome the problem associated with plastic waste. In India huge number of plastics are used for various purposes such as for making of water bottle, soda bottle & bag, etc. which are not disposable. Because of these various problems occurs below. After studying the problem, we developed the effective way to overcome this problem. Bottle brick are light in weight and withstand high amount of load or pressure. Eco-bricks, polyethylene terephthalate (PET) bottles filled with mixed inorganic waste, have become a low-cost construction material and a valid recycling method to reduce waste disposal in regions where industrial recycling is not yet available. Because Eco-bricks are filled with mixed recovered materials, potential recycling of its constituents is difficult at the end of its life
Kepala Desa Perempuan dan Local Strongman: Membunuh Atau Menyuburkan Patriarki di Desa Cijaku Kecamatan Cijaku Kabupaten Lebak
Authors: Wawan W. , Rosyid Mohamad Iyos
Published: March 2023

Tulisan ini berusaha membedah keterpilihan dan kepemimpinan kepala desa perempuan di Desa Cijaku dengan juga menelisik peran Local Stongman dibelakangnya. Dimana dalam upaya membedah dan mengupas topic pada tulisan kali ini penulis menggunakan beberapa kajian teori diantaranya teori Joel S. Migdal mengenai Local Strongman dan juga kajian teori kepemimpinan perempuan. Penelitian menggunakan metode kualitatif deskriptif dengan wawancara dan observasi partisipatoris. Dari penelitian ini dihasilkan temuan berupa adanya pengaruh Local Strongman dalam kemenangan Heni Hendrawati sebagai kepala desa perempuan di desa Cijaku. Peran tersebut sangat berpengaruh signifikan karena berhasil memutus rantai kepemimpinan dari aktor laki-laki yang memunculkan sebuah pemimpin perempuan dengan usia yang relative sangat muda pada kemenangan di periode pertama, namun kemenangan ini juga tidak luput dari peran laki-laki sebagai Local Strongman yang memobilisasi masa dengan kontrol yang dimilikinya, Lokal Strongman disini adalah ayah dari Heni yang dikenal dengan julukan Ama Ekeng. Jadi kehadiran Kepala desa perempuan di Desa Cijaku justru menggunakan peran dari Patriarki untuk menggalang kekuatan politik. Dari sisi kepemimpinannya sebagai perempuan peneliti menemukan sebuah temuan dari hasil observasi langsung berupa sangat minimnya program atau inovasi baru dari Heni Hendrawati untuk menarik partisipasi perempuan. Kehadiran pemimpin perempuan di Desa Cijaku pada faktanya tidak memberi perubahan signifikan terutama pada isu-isu atau kebijakan pemberdayaan perempuan. Bahkan selama menjadi Kepala Desa selama dua periode, Ia tidak pernah menggunakan kewenangannya membuat peraturan berskala desa.
Gestión de la innovación tecnológica - líneas de financiamiento tecnológico a nivel nacional, provincial y municipal en la ciudad de Río Gallegos
Authors: Ojeda Sebastián , Villegas Rita Mabel
Published: March 2023

El propósito de este trabajo consistió en reconocer y analizar el financiamiento vigente durante los años 2015-2019 para las pequeñas y medianas empresas (PyMEs), en las líneas de crédito vinculadas a la gestión de la innovación tecnológica a nivel nacional, provincial y municipal a las que pudieron acceder los empresarios de la ciudad de Rio Gallegos, En cuanto al contenido, se analizó el marco legal y las oportunidades de financiamiento para las PyMEs de la localidad, lo cual resultó de suma importancia para comprender, mediante esta investigación, las bases de la legislación vigente ligadas al tema, destacándose entre ellas las leyes a nivel nacional Nº 23.877 y Nº 25.467 y los programas provinciales en práctica propuestos por el Ministerio de Producción, Comercio e Industria. Se pudo identificar, en las entidades que actúan como autoridades de aplicación, la existencia del lanzamiento de diferentes convocatorias para acceder por parte de los PyMEs a financiamientos. Asimismo, se descubrió la existencia de varias líneas de créditos e incentivos y se logró exponer las principales que fueron ofrecidas por el estado, tanto nacional como provincial, las cuales resultan ser variadas y se ajustan, de manera directa o indirecta, a la gestión de innovación tecnológica de las PyMEs.
Gas de Argentina, realidades y ficciones en senderos que se bifurcan
Authors: Carrizo Silvina Cecilia , Velut Sébastien , Villalba María Sofía
Published: March 2023

Argentina busca poner en valor hidrocarburos no convencionales en NorPatagonia, los que pueden contribuir a paliar los déficits energéticos y fortalecer los sistemas existentes. Implica la reactivación de lugares productivos y aprovecha recursos estratégicos para las matrices energéticas argentina y mundial. Al mismo tiempo, en el país, se apalanca la explotación de fuentes renovables. El objetivo del artículo es reflexionar acerca de los procesos de transición energética y la dependencia a los sistemas tradicionales. Se busca comprender la (re)configuración del espacio a distintas escalas -local, regional y nacional- y cómo interactúan las nuevas organizaciones productivas, con las heredadas. La explotación de gas no convencional en la región NorPatagónica, ejemplifica cómo se refuerza la dependencia a los sistemas tradicionales, a la vez que se apuesta a la innovación, con proyectos que muchas veces no se concretan. La realidad de los senderos consolidados y sus bifurcaciones contrasta con numerosas ficciones que se crean en torno a los recursos energéticos.
Los concejales de mandato cumplido y la ejecución presupuestaria. El caso de la Cuenca Carbonífera.
Authors: Oyarzún Vera Marcos Gumercindo , Huanca Sabina Mamaní , Balderrama María Magdalena , Noriega Cintia Soledad , Molina Florencia Anabel , Cerezo Claudia Beatriz , Elguero Lourdes Evangelina , Alvarado Carlos Ariel , Barrios Eduardo Alejandro , Ríos Daniel Martin , Castellón Héctor Ricardo , Barros José Alejandro , Cabezas Ramiro Javier
Published: March 2023

El trabajo de los ediles, en tanto participan del proceso presupuestario, se ve envuelto en una serie de problemáticas que le son propias. Y ello afecta a la comunidad a la cual representan, si no pueden sortear dichas cuestiones. Los ediles realizan su trabajo, en tanto se encuentra relativamente normado por la reglamentación vigente. Las frecuentes situaciones que se encuentran nos indican que entre las cuestiones reales con las que se manejan y las normas existe un distanciamiento o brecha.

El objetivo se centra en identificar la existencia de la brecha entre ambas circunstancias y sus efectos en la labor de los concejales de mandato cumplido en la Cuenca Carbonífera. Por lo tanto, nuestra pregunta principal es ¿existe una brecha entre lo normado y el trabajo real que realizan los concejales cuando se encuentran en el proceso de aprobación del presupuesto que deviene del poder ejecutivo municipal? Entendemos que esto afecta la toma de decisiones de la principal herramienta de trabajo que afecta a ambas poblaciones.

Para afrontar dicha pregunta se utilizó un cuestionario dirigido a los concejales que ya no están en funciones, constando de seis ejes de preguntas.  Con ello accedimos a sus experiencias personales y de las distintas visiones y maneras de abordar la cuestión. Las respuestas condujeron a situaciones donde predominaron problemáticas derivadas principalmente de las líneas políticas, informacionales, recursos y de preparación personal para los cargos de ediles.

Teniendo en cuenta ello, la situación de la existencia de la brecha queda demostrada y el paso siguiente será establecer si los ediles y la comunidad aceptan y mantienen estas peculiaridades para el presupuesto. Las próximas líneas de investigación serán relativas a los posibles cambios a introducir en el proceso a nivel práctico y normativo.
Métricas de APIs: Catálogo y Herramienta OMA
Authors: Paredes Uriel , Juan Enríquez , Casas Sandra
Published: March 2023

En la actualidad, las APIs web tienen un gran valor para el desarrollo de aplicaciones, ya sean web, cloud, móvil, u otras. Cumplen un papel de suma importancia, y son utilizadas ampliamente por grandes empresas alrededor del mundo, tales como Google o Amazon. Las métricas permiten analizar o cuantificar distintas cualidades del software, por lo que resultan de gran utilidad para realizar estimaciones y planificación, evaluaciones objetivas, o asegurar la calidad en el desarrollo de APIs web. Este trabajo presenta un catálogo de 37 métricas de APIs clasificadas por diversos criterios y la herramienta OMA, que calcula automáticamente 14 métricas de APIs web usando como entrada la especificación OpenAPI.
Generación de competencias digitales para la autonomía en la oralidad en Lengua Extranjera
Authors: Román Sandra , Vilanova Gabriela , Varas Jorge
Published: March 2023

Las posibilidades que las TIC pueden aportar a la formación y a la educación han sido tratadas en diferentes trabajos (Cabero, 2001, 2007; Martínez y Prendes, 2004; Martínez, 2008), se pueden señalar como las ventajas  más significativas: ampliación de la oferta informativa, creación de entornos más flexibles para el aprendizaje, eliminación de las barreras espacio-temporales entre el profesor y los estudiantes, incremento de las modalidades comunicativas, potenciación de los escenarios y entornos interactivos.

En la enseñanza de lenguas extranjeras la pronunciación constituye un aspecto fundamental para el desarrollo de la oralidad. Está relacionada con la incorporación de rasgos segmentales y suprasegmentales para lograr la inteligibilidad. El uso de la tecnología en este contexto tiene una larga trayectoria y constituye un recurso muy valioso para el proceso de enseñanza y aprendizaje. Sin embargo, no garantiza que contribuya a la autonomía si no se cuenta con las competencias digitales requeridas tanto por los estudiantes como los docentes para que se logre el aprendizaje.

Este estudio pretende hacer un análisis de diferentes recursos tecnológicos accesibles, desde la perspectiva del aprendizaje híbrido, para determinar cuáles reúnen las condiciones tanto para favorecer el desarrollo de la pronunciación como para promover el aprendizaje autónomo. El mismo se enmarca en un plan de beca de iniciación a la investigación para estudiante de posgrado de la Maestría en Educación en entornos virtuales en el contexto del proyecto de investigación Tipo I PI29b254 titulado “Integración de Sistemas de Gestión del Aprendizaje (LMS) y entornos de web social en la Educación Superior” (Universidad Nacional de la Patagonia Austral)  y se tuvieron en cuenta las experiencias en la asignatura Fonética y Fonología Inglesa II de las carrera de Traductorado, Licenciatura y Profesorado en Lengua Inglesa en la Universidad Nacional de La Rioja.
Documenting Non-Sonic Music
Authors: Paul Norman  , Michael Wolters  , Andy Ingamells
Published: March 2023

How to document music with non-sonic elements? Or: How to document all the performative qualities of a piece of music that can’t be heard? Beginning with this question our group of researchers, filmmakers and dramaturgs from Birmingham (UK), Frankfurt (Germany) and Fredrikstad (Norway) met between 2019 and 2021 to develop initial ideas and questions, then test them.
Seasonal variations of plant species diversity and phylogenetic diversity in abandoned farmland of China's Huang-Huai Plain
Authors: Yan Peisen , Lu Xunling , Li Wanying , Zhang Jian , Li Peikun , Li Yan , Wang Kaiyue , Ding Shengyan
Published: March 2023

As urbanization and industrialization continue to advance rapidly in
China, the issue of farmland abandonment is becoming more prevalent.
Nevertheless, this phenomenon is crucial in protecting plant diversity
in agricultural landscapes. This study sought to investigate the
seasonal variation patterns of plant diversity in abandoned farmland
habitats within the Huang-Huai Plain region. The plant community
characteristics during spring, summer, and autumn were examined, and the
variations in plant species diversity and phylogenetic diversity were
analyzed across the different seasons. Spearman correlation analysis was
used to explore the interrelationships among various diversity indices,
and redundancy analysis and linear regression were employed to examine
the connection between plant diversity indices and key soil
environmental factors. The results showed that significant seasonal
changes occurred in the plant community characteristics of abandoned
farmland in the Huang-Huai Plain, with the number of families, genera,
and species being highest in spring, followed by summer and autumn.
Similarly, plant species diversity, richness index, and phylogenetic
diversity were also higher in spring than in summer and autumn. The
phylogenetic structure of plant communities tended to diverge in spring,
be random in summer, and be clustered in autumn. The phylogenetic
diversity and species diversity indexes were strongly associated, and
soil organic matter and ammonium nitrogen were significantly positively
correlated with plant species diversity and phylogenetic diversity. This
study highlights the importance of considering seasonal and temporal
scales when studying plant diversity and provides a theoretical basis
for biodiversity conservation and agricultural production in the
Huang-Huai Plain of China.