bluuebunny/crossref_metadata_2025 huggingface dataset:
Examining the Relationships Between Sleep Physiology and the Gut Microbiome in Preclinical and Translational Research: Protocol for a Scoping Review (Preprint)
Authors: Maki Katherine Anne , Alkhatib Jenna , Butera Gisela , Wallen Gwenyth Reid
Published: April 2022

BACKGROUND

Sleep is an instrumental behavioral state with evidence supporting its active role in brain function, metabolism, immune function, and cardiovascular systems. Research supports that there are pathways underlying the bidirectional communication between the brain and gastrointestinal system, also known as the “gut-brain axis.” Primary research examining sleep and gut microbiome relationships continues to increase. Although current data include both preclinical and clinical research, gut microbiome results are reported through a wide range of metrics (alpha diversity, beta diversity, and bacterial compositional changes), which makes cross-study comparison challenging. Therefore, a synthesis of the research examining sleep and gut microbiome relationships is necessary to understand the state of the science and address gaps in the literature for future research.

OBJECTIVE

In this paper, we outline a scoping review protocol to evaluate and synthesize preclinical and clinical primary research focused on the associations between sleep and the gut microbiome.

METHODS

The search strategy was facilitated through a medical research librarian and involved electronic databases including PubMed/MEDLINE, Embase, Scopus, Web of Science, CENTRAL trials database, BIOSIS Citation Index, and the Zoological Record. Gray literature sources including medRxiv and bioRxiv preprint servers were also searched. Studies were screened according to the aims and exclusion and inclusion criteria of the protocol. After screening, data will be extracted and synthesized from the included studies according to predefined sleep and microbiome methodology metrics.

RESULTS

The search strategy yielded 4622 references that were imported for study screening, and source screening was completed in May 2022 by 2 independent investigators, resulting in a total of 93 sources for data extraction and synthesis. The data synthesis table is expected to be completed by August 2022, and the results will be disseminated through paper submission by December 2022 and presented at conferences related to neuroscience, sleep physiology, bioinformatics, and the microbiome.

CONCLUSIONS

A scoping review of preclinical and clinical research is needed to synthesize the growing data focused on the relationships between sleep and the gut microbiome. We expect the results of this synthesis will identify gaps in the literature and highlight pathways linking the gut-brain axis and sleep physiology to stimulate future research questions.

CLINICALTRIAL

Open Science Framework 69TBR; https://osf.io/69tbr

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/38605
A new option in pain prevention with a therapeutic virtual reality solution in bone marrow biopsy context: results of an open-label randomized multicenter phase III study (REVEH Trial) (Preprint)
Authors: Le Du Katell Genovefa , Septans Anne-Lise , Maloisel Frédéric , Vanquaethem Hélène , Schmitt Ana , Le Goff Marielle , Clavert Aline , Zinger Marie , Bourgeois Hugues , Dupuis Olivier , Denis Fabrice , Bouchard Sr Stéphane
Published: April 2022

BACKGROUND

Evidence regarding the analgesic effect of distraction through immersion in virtual reality (VR) for care-induced pain, has been documented in several phase II trials but comparison with standard treatments in large-randomized studies are needed.

OBJECTIVE

In this open-label multicenter randomized phase III trial (ClinicalTrials.gov identifier: NCT 03483194), we evaluated the safety and efficacy of a novel VR therapy solution for distraction in the context of bone marrow (BM) biopsy.

METHODS

Bliss© is a VR software with four imaginary interactive environments in three dimensions with a binaural sound (head-mounted display). Efficacy was evaluated on pain intensity using a visual analog scale (score from 0-10) immediately after the biopsy. The primary endpoint was patient-assessed pain intensity after BM procedure, with a visual analog scale (VAS). Secondary endpoints were anxiety and tolerance. Overall, 126 patients with previously documented untreated or suspected malignant hemopathy between September 6, 2018, and May 18, 2020, were randomly assigned in a 1:1 ratio to receive pain prevention with a mixture of nitrous oxide/oxygen (MEOPA) (n=63) or VR (n=63) before and during BM biopsy. All patients received local anesthesia (lidocaine) before biopsy. Modified intention-to-treat analysis was performed.

RESULTS

Participants’ median age was 65.5 (range 18-87) years and 54.2% of patients were male.
The average pain intensity was 3.5 (SD 2.6) for the MEOPA group and 3.0 (SD 2.4) for the VR group without any significant difference in age, sex, center or hemopathy (P=.26). Concerning anxiety, 67.5% of patients were afraid before the biopsy and anxiety scores were moderate to very high in 26.3% of patients before the biopsy (fear of pain and revised STAI questionnaires) and 9.0% after the biopsy for all patients without any significant difference between the 2 groups (P=.83). Immersion in VR was well tolerated by the majority of patients in the VR group.

CONCLUSIONS

The intensity of pain and did not significantly differ between both arms. VR was well tolerated, and satisfaction of patients, nurses and physicians was very high. Virtual reality could be an alternative treatment in case of contraindication or intolerance to MEOPA.

CLINICALTRIAL

ClinicalTrials.gov identifier: NCT 03483194
Cluster patterns of acute stroke patient-reported symptom terms and expressions around stroke diagnoses and neuroimaging measures: A mixed methods exploratory study protocol (Preprint)
Authors: Brown Gretchel , Lopez Emme , Dula Adrienne N
Published: April 2022

BACKGROUND

Neuroimaging has become a standard modality for accurate assessment of stroke because it can reflect cerebrovascular tissue pathophysiology and predict stroke outcome. Computed tomography (CT) and magnetic resonance imaging (MRI) scans provide diagnostic information to objectively identify salvageable brain tissue, allowing care teams to successfully select patient who will benefit from therapy. Accurate imaging assessment is important for individualized management of patients with stroke, whose symptom reports are often the initial trigger for acute stroke care encounters.

OBJECTIVE

The purpose of this mixed methods exploratory study is to assess if defined sets of patient-reported stroke symptom terms and expressions in free-text unstructured documentation within electronic health records (EHRs) map to stroke diagnoses, neuroimaging qualitative descriptors and quantitative lesion measures in acute stroke patients seen in four hospital emergency departments of an urban regional health care system.

METHODS

A corpus of EHR data will be created from a pre-existing cohort of 639 de-identified patient EHRs included in the retrospective arm of the WISHeS (Women’s Imaging of Stroke Hemodynamics Study) study from January 2015 to January 2019. Patient-reported symptoms and expressions within free-text unstructured documentation in EHR forms for patient care encounters will be mapped to (a) the stroke diagnosis as documented by the stroke specialist following physical assessment and imaging review; (b) CT and MRI qualitative descriptors of stroke lesion location, quality and severity as written in imaging reports; and (c) neuroimaging gold standard quantitative measures of perfusion delay, lesion volume, and cerebral collateral function. Findings will be synthesized into a tripartite stroke type taxonomy that includes a qualitative stroke type data cluster taxonomy, a quantitative stroke type data cluster taxonomy, and a mixed stroke type data cluster taxonomy. Exploratory factor analysis will then be applied to the mixed stroke type data cluster taxonomy to elucidate the strength of relationships between qualitative and quantitative variables. This will allow us to identify which defined sets of patient-reported symptom terms and expressions are most associated with stroke diagnoses and neuroimaging measures as classified by stroke type.

RESULTS

We anticipate finalizing data selection for inclusion in our corpus by May 2022, and completing our data analysis by October 2022. Findings will be used to inform the development of pre-neuroimaging decision-making algorithms for stroke treatment. These algorithms have great potential for aiding timely diagnosis in circumstances when access to neuroimaging is delayed or unavailable.

CONCLUSIONS

Not applicable. We plan to report results in a follow-up paper no later than October 2022.

CLINICALTRIAL

N/A
Bluetooth Controlled Solar Grass Cutter using IOT Application
Authors: Napte Prof. Kiran , Yevale Pooja , Raje Pranali , Temgire Divya
Published: April 2022

Abstract: The basic project idea is to develop a grass-cutting robot controlled with help of the android application. Here the Bluetooth module is used to connect raspberry pi with the phone and in which the reading of the ultrasonic sensor is stored on IOT platform i.e think speak. Previously the grass cutter machines are operated by fuel which is costly. Here the solar panel is utilised to charge the battery so that it doesn't have to be charged externally .The sun-based energy source is more straightforward to utilize, more profitable contrasted with other energy and it is not difficult to work. By the use of solar panels, we can use sunlight to generate electricity free of cost. The solar panel is used to charge the battery for grass cutting purposes. The movement of the machine is totally controlled by using the Android app. The controlling device of the system is Raspberry pi. Bluetooth module and DC motors are interfaced to the Raspberry pi. The data received from the android phone application by the Bluetooth module is given as an input to the Raspberry pi and the controller acts accordingly on the DC motor of the solar grass cutter. And also here at the input, we have connected an ultrasonic sensor for obstacle detection whenever the obstacle is detected the raspberry pi sends the command to stop the machine in its place and the reading of the ultrasonic sensor is stored on the cloud. Keywords: Raspberry pi, Solar panel, Bluetooth module, Wi-Fi module, Dc motors.
Techno-Pedagogical Skills of Teacher Educators with Special Reference to E-Learning
Authors: Kumari Miss Poonam , Rani Dr. Manisha
Published: April 2022

Abstract: “The art of teaching is the art of assisting discovery.”- Mark Van Doren The term "techno-pedagogy skills" refers to the ability to use technology for pedagogical purposes as well as the ability to integrate technology into the classroom. It is a mixed or hybrid teaching method in which electronic resources or information and communication technology (ICT) are used in the learning process. These skills guide the teaching experience in an effective manner. Technical teaching skills are very much necessary for making the teaching process an enjoyable experience as it will significantly change the teacher's mode of interaction. While technical pedagogy is a boon in the teaching process, and circumstances such as the pandemic have increased the value or importance of these skills as virtual classes replace face-to-face classes, but the truth is that due to lack of knowledge about technical teaching skills, teachers are not using these skills correctly. There are so many reasons which are responsible for this condition. But in the present scenario the knowledge of teachers regarding techno-pedagogical knowledge demands focused attention as it is one of the basic or primary necessities in practicing the skills. This paper presents about the importance of techno-pedagogical skills of Teacher Educators with reference to elearning. Keywords: Techno-Pedagogical skills, Teacher Educators, E-learning
Multicrop Harvesting Machine
Authors: Wagode Akash , Thakre Vaibhav , Khairkar Yeshwant , Girde Sunil
Published: April 2022

Abstract: Overall the world, India is not only the largest producer of many crops like wheat, rice, pulses but also exporter of many crops. The Indian economy finds its roots in agriculture. In farming, crop cutting is an essential part of farming as well as a very time consuming process. Harvesting is an important part of the agriculture industry. Nowadays modern harvesting technology is increasing but its cost is very high and skilled laborers are required to operate the machines. To minimize the lengthy process of harvesting and reduce the cost of skilled laborers to operate machines. We have designed the “MULTICROP HARVESTING MACHINE” so it can eliminate skilled laborers as well as it saves the time of farmers so they can focus more on good crop production. This machine uses the solar panel to power the drive cutter from the wheels of the vehicle itself. This project targets the small field crop cutter machine for small height & small stream crops. This machine is economical and helps the farmers to achieve higher productivity. Keywords: Small Scale, Solar Panel, Wheels
LEO based Satellite Navigation and Anti-Theft Tracking System for Automobiles
Authors: Bodhare Hemant Gautam , Ansurkar Asst. Prof Gauri
Published: April 2022

Abstract: GPS and Inertial Navigation Systems (INS) are used today in automobile navigation and tracking systems to locate themselves in Four Dimensions (latitude, longitude, altitude, time). However, GNSS or GPS still has its own bottleneck, such as the long initialization period of Precise Point Positioning (PPP) without dense reference network. For navigation, a number of selected LEO satellites can be equipped with a transmitter to transmit similar navigation signals to land users, so they can act like GNSS satellites but with much faster geometric change to enhance GNSS capability, which is named as LEO constellation enhanced GNSS (LeGNSS). This paper focuses on Low Earth Orbit navigation and anti-theft tracking system in automobiles that represents a framework which enables a navigating vehicle to aid its Inertial Navigation System when GNSS or GPS signal becomes unusable. Over the course of following years LEO satellite constellation will be available globally at ideal geometric locations. LEO Satellite aided Inertial navigation system with periodically transmitted satellite positions has the potential to achieve meter-level-accurate location. Keywords: LEO constellation, LEO enhanced GNSS (LeGNSS), Precise Point Positioning (PPP), Inertial Navigation System (INS), Precise Orbit Determination (POD)
Recipe Recommendation by Ingredients Detection
Authors: Dmonte Mrs. Silviya , Chudasama Mrs. Parth , Turakhia Mrs. Meet
Published: April 2022

Abstract: Cooking is a daily chore for many individuals and hence can become a monotonous activity. Sometimes it is difficult for one to decide what new & interesting can be cooked from the available ingredients. Lack of culinary expertise can lead to disproportionate use of ingredients resulting in wastage. Also while cooking, one’s hands are unclean to be able to look the recipe in their smart device or recipe books. For beginners cooking can also become a hassle because they might not know names of many ingredients. Our proposed system intends to help everyone with their daily cooking. Using our application one will be able to escape their monotonous cooking routine by using ingredients detection system along with recommendation model. Using our application user will be able to scan the available ingredients through which we will recommend best suitable recipe for them. For detecting the ingredients we will apply CNN algorithm with parameter optimization. CNN is the state-of-theart approach to the deep learning, with significantly higher accuracy then traditional support-vector-machine-based algorithm. Our application will store the detected ingredients of the user in the database and recommend recipe accordingly in the home page. Further recommendation on the home page would be based on the historical patterns of the user, while recommending we will be using various factors such as cuisine preference, ingredients, cooking time, etc. Using NLP we will serve the voice control feature to the users through which they will be able to hear the recipe at their own pace, in case their hands are unclean. Through NLP our motive is to overcome the regional barrier so anyone unfamiliar with English will also be able to use our application and can experience the culture of different regions through their cuisine. Keywords: object detection, deep learning, convolution neural network, recipe recommendation, natural language processing, voice assistance, hybrid based recommendation.
Boburnoma and World Literature
Authors: Guzal Umurova
Published: April 2022

Abstract: The article provides information about the work of the king and poet Zahiriddin Muhammad Babur. The poet's work "Boburnoma" and its peculiarities, as well as views on the position of this work in world literature are analyzed. The current relevance of the valuable information in the work "Boburnoma" is noted. Keywords: cultural heritage, unique talent, mummified work, literary views, talent, culture of nations.
PSICOMOTRICIDADE E PARADIGMA DA COMPLEXIDADE
Authors: Fernandes Jorge , Veiga Guida , Filho Paulo Gutierres
Published: April 2022

The aim of this article is to reflect about the relevance of incorporating the paradigm of complexity in psychomotor thinking, which involves different epistemic frames. It describes the simplifying thinking that reduces and fragments the different areas of knowledge, as opposed to complex thinking, which integrates them in a systemic way. At the same time, it presents a reflection about its possible influences on the foundation of psychomotricity as a health area practice. It is concluded that complex thinking is useful in the transdisciplinary foundation of psychomotricity and structuring of psychomotor praxis to meet the needs, specificities and psychomotor performance of each human being.
Архитектура как феномен эволюции Универсума. Часть 1
Authors: Ткачёв Валентин
Published: April 2022

В качестве материализованного объекта человеческой деятельности по организации среды обитания архитекту­ра представляет многомерное информационное поле для исторического и синхронного анализа по всем разделам со­временной научной методологии, обновляющейся в теориях хаоса, фракталов, в сфере исследований самоорганизующихся систем, потоки развития которых входят в общее русло эво­люции мироздания. Расширение горизонта знаний о микро- и макромире приводит к пониманию того, что естественная на этапах становления науки углублённая специализация дисциплин сегодня неизбежно упирается в необходимость обобщения, выявления единых закономерностей их бытия, отхода отудовлетворённости успехами разобщённых отрас­лей знаний. Известный английский физик Р. Пенроуз сетовал по поводу того, что современная наука похожа на одеяло, сшитое из лоскутов.

Организованные системы косного, органического и со­циального мира, демонстрирующие разнообразие форм и моделей существования, являют собой произведения дей­ствующих в мире всеобщих закономерностей Универсума. В том числе и архитектура, на объектах которой как на модели мы воочию наблюдаем действие этих закономерностей, ибо о морфогенезе космических тел и микромире можно судить дистанционно и в основном по гипотезам.
Цифровая архитектура
Authors: Дубынин Николай , Кочешкова Екатерина , Граник Михаил , Родимов Антон
Published: April 2022

Внедрение технологий информационного моделирования (ТИМ) является одной из современных тенденций развития архитектурного проектирования, определяющей вопросы разработки и оформления проектной документации, посте­пенно становясь обязательным условием её реализации в виде строительной информационной модели - БИМ (BIM). Процесс перехода к новым методам ведения проектирования формально стал важным показателем в официальной оценке эффективности работы строительной отрасли в целом и архи­тектуры в частности. Однако активное применение новых ин­струментов проектирования требует обоснования таких важных показателей их применения на практике, как эффективность, безопасность,технические и этические ограничения.

В целях выявления реальной картины в данной обла­сти проанализирована информация, содержащая мнения исследователей и специалистов и экспертные оценки по проблемным вопросам внедрения ТИМ. При этом выявлена тенденция искусственного стимулирования данного процесса на разных уровнях управления строительством на основе оптимистичных оценок его эффективности. Проблема за­ключается в организации широкомасштабного эксперимента по внедрению цифровых технологий при отсутствии опыта апробации достаточного для обоснованной оценки предпо­лагаемых результатов.

Анализ существующих возможностей, проблем и пер­спектив развития новых методов в архитектурном проек­тировании позволяет определить целесообразную степень их внедрения.
Эволюция палладианской архитектурной традиции Германии конца XVII – середины XIX века
Authors: Цветкова Полина
Published: April 2022

Палладианское архитектурное направление развивалось на территории Германии с конца XVII века и фактически оставалось влиятельным вплоть до второй половины XIX столетия. Изучая особенности хронологического развития стиля, специфику его авторских интерпретаций, автор стремится к выделению характерных черт немецкой национальной ветви палладианства. На примере творчества архитекторов И.А. Неринга, Г.В. Фон Кнобельсдорфа, Ф.В. Эрдманнсдорфа, К.Л. Хильдебрандта, Я. Боумана, К.Ф. К. фон Гонтарда, Д. Гилли, С.Л. дю Ри, К. фон Фишера и мастеров переходного к эклектике периода – Ф. Гилли, К. Ф. Шинкеля, И. Я. Ф. Вайнбреннера – прослеживаются история интерпретации палладианского наследия, поиски новых архитектурных решений, периоды развития немецкой архитектуры.
Опыт урегулирования застройки на Адмиралтейском острове. 1805–1840-е годы
Authors: Молоткова Елена
Published: April 2022

Подчёркивается, что ценностью исторического наследия Санкт-Петербурга является не только феномен его городской застройки, но и специфический механизм урбанизации, позволявший целенаправленно формировать уникальные архитектурные ансамбли. Рассматриваются обстоятельства градостроительных процессов реконструкции части территории между Невой и Мойкой, которые привели к появлению крупного регулярного градостроительного комплекса, соответствующего критериям центра столичной метрополии. Особое внимание уделяется балансу открытых и закрытых пространств, условиям развития инфраструктуры.
Multi-modal imaging reveals a small subpopulation of Deinococcus radiodurans exhibiting correlated metabolic activities
Authors: Zhu Weinan , He Xinyu , Li Haoran , Jiang Bo , Xie Ruo-Chen , Wang Wei
Published: April 2022

Since a polyvalent strategy has recently been assumed to be adopted by
Deinococcus radiodurans that can generate various resistance against
many different detrimental sources of oxidative damage (e.g. reactive
oxygen species, heavy metal ions and ionising radiation), investigating
more than one restorative metabolic activities and their interrelation
of the very same entities of Deinococcus radiodurans is of great
significance for exploring its polyextremophile nature, which will be
insightful for obtaining fundamental generic insights into life
sustainability. Herein, we apply mainly fluorescence microscopy and back
reflection microscopy to visibly assess the respective activities of
superoxide radical generation and silver ion metabolism for individual
Deinococcus radiodurans. Strikingly, only a minority (<20%)
of the bacteria which show low superoxide radical levels is revealed to
exhibit considerable formation of silver nanoparticles whilst those
containing more superoxide radicals all show minimum silver ion
metabolism. The discovery of the strong negative correlation for the
small subpopulation between the two visualised different metabolic
activities not only provides direct experimental evidence in terms of
bacterial functionality for the inferred survival regime of the extreme
microbe, but also suggests a new way of chemically examining biology
from the perspective of inter-functional relationship.
The Lie symmetry analysis, exact solutions and conservation laws for variable coefficients Broer-Kaup-Kupershmit equation
Authors: Liu Jinzhou , Yan Xinying , Jin Meng , Xin Xiangpeng
Published: April 2022

In this article, the (2+1) - dimensional variable coefficients
Broer-Kaup-Kupershmit equation is studied for the first time by Lie
symmetry analysis. The derivation process of generating elements of
vcBKK equation is given systematically, and the optimal system of the
one-dimensional subalgebras is determined. Furthermore vcBKK equation is
reduced based on the optimal system, and then the reduced equations are
solved with the help of the (G’/G)-expansion method. The images of
various kinds of exact solutions are drawn. Finally, according to the
conservation theorem, the conservation laws of vcBKK equation is
constructed.
Comprehensive Therapy for Infant Vascular Tumor Associated with Kasabach-Merritt Phenomenon -- Single Center Primary Experience
Authors: Sun Xiaoting , Xu Miao , Lv Kaiyang , Ma Xiaorong , Wu Liming , Ouyang Tianxiang
Published: April 2022

Background: This study aimed to introduce our single-center experience
of infant vascular tumor associated with Kasabach-Merritt phenomenon
(KMP) which received combined medicine treatment with intralesional
laser photocoagulation (ILP) and sclerotherapy. Methods: A retrospective
study was conducted of medical records of all children with diagnosis of
KHE or TA associated with KMP treated with medicine treatment,
intralesional laser photocoagulation (ILP) and sclerotherapy between
February 2017 to November 2020. Clinical features, response to
comprehensive therapy and outcomes were recorded. Results. Twenty-three
patients, including nine females (39%) and fourteen males (61%), were
identified. The mean age was 6.9 months (age range, 11 days to 2 years)
at the time of treatment. Nine children (39%) demonstrated sensitivity
to single corticosteroid therapy. Fourteen children (61%) received
combining therapy with intravenous VCR and corticosteroid therapy. All
children had at least two ILP and sclerotherapy performed, with a mean
of 3.5 procedures (range: 2-6). Of these 14 children, only one
experienced a relapse of thrombocytopenia and the remaining 13 children
had no clinical symptoms recurred but non-involuting tumor. Conclusions.
The combined therapy modalities could induce a more rapid tumor response
and resolution of KMP, decrease the rebound rates. The precent research
presents a noval and safe multi-modality treatment for infant vascular
tumor associated with KMP.
A Cardiac Time Bomb Triggered by Septic Coronary Embolism
Authors: Nakasone Kotaku , Konagai Nao , Ichimoto Eiji , Hasegawa Atsushi , Kabasawa Masashi , Sugimoto Koichi , Miyahara Hirofumi
Published: April 2022

A 45-year-old man was affected by myocardial infarction (MI) associated
with infective endocarditis. His myocardium was destroyed slowly, and
giant myocardial pseudoaneurysm was found to be waiting to go off six
weeks after index MI.
Ecosystem modeling reveals extensive soils that could support globally rare pine barrens and sandplain ecosystems in New York State
Authors: Corbin Jeff , Flatland Emma
Published: April 2022

Pine barren and sandplain ecosystems are unique, globally rare
ecosystems whose open-canopied vegetation structure supports a unique
assemblage of plants and animals. They occur almost exclusively on deep,
sandy soils, and require periodic disturbances to prevent succession to
forest. Though these ecosystems, and the unique species that live in
them, are rare today, they once occupied a larger area of coastal and
interior New York and New England. In order to better understand pine
barren and sandplain distribution in the past, and the potential for
restoring them in the future, we mapped the distribution of soils in New
York State that can support these ecosystems. We quantified soil percent
sand and soil depth of 156 known high quality remnant pine barren and
sandplain ecosystems to calculate threshold soil characteristics. We
then mapped all soils in the state that were at least as sandy and deep
as the threshold values we calculated. The total area of our map of
potential soil conditions was over 9,500 km2, made up of forested
(57%), urban (26%), agricultural (13%) and open (4%) land cover.
Nearly 7,000 km2 – almost 20 times the area of known, high quality
remnant ecosystems – of land was forested, agricultural, or open land.
Existing examples of pine barren and sandplain ecosystems were mostly
embedded within much larger matrices of forest, agriculture, and urban
land cover that shared the distinctive soil conditions. The presence of
extensive soils in coastal and interior New York that, with the
appropriate disturbance regime, have the potential to host pine barren
and sandplain ecosystems offers a new perspective on these ecosystems’
distribution in the past – and about how to better align restoration
and conservation to preserve the future.
A triplex PCR method to detect gene insertion for the distinction of African swine fever virus wild-type versus deletion strains
Authors: Huang Zhao , Xu Zhiying , Cao Haoxuan , Zeng Fanliang , Wang Heng , Gong Lang , Zhang Shengxun , Cao Sen , Zhang Guihong , Zezhong Zheng
Published: April 2022

To date, there is no effective vaccine or antiviral therapy available to
prevent or treat African swine fever virus (ASFV) infections. ASFV gene
deletion strains have been proposed as promising anti-ASFV vaccine
candidates. In recent years, most ASFV gene deletion strains worldwide
have been recombinant strains expressing EGFP or mCherry
as markers. However, a method for their wide range detection is still
lacking. Therefore, in this study, a new triplex real-time PCR (RT-PCR)
method was established for the broad and accurate differentiation of
ASFV wild-type vs. gene deletion strains. We designed three pairs
of primers and probes to target B646L, EGFP, and
mCherry, and RT-PCR was used to detect these three genes
simultaneously. The detection method prevented non-specific
amplification of porcine reproductive and respiratory syndrome virus,
porcine epidemic diarrhea virus, circovirus type 2, pseudorabies virus,
and classical swine fever virus genes. The minimum copy number of
standard plasmid DNA detected using triplex RT-PCR was 9.49, 30.20, and
9.60 copies for B646L, EGFP, and mCherry,
respectively. Importantly, of the 1646 samples analyzed in this study,
67 were positive for ASFV, all corresponding to the wild-type virus.
Overall, our data show that the triplex RT-PCR method established in
this study can specifically identify both ASFV wild-type and gene
deletion strains.
Influence of oxide thickness variation on analog and RF performances of SOI FinFET
Authors: Tripathy Dhananjaya , Acharya Debiprasad , Rout Prakash , Biswal Sudhansu
Published: April 2022

This paper focuses on the impact of variation in the thickness of the oxide
(SiO2) layer on the performance parameters of a FinFET analysed by varying
the oxide layer thickness in the range of 0.8nm to 3nm. While varying the
oxide layer thickness, the overall width of the FinFET is fixed at a value
30nm, and the FinFET parameters are analysed for structures with different
oxide layer thickness. The parameters like drain current, transconductance,
transconductance generation factor, parasitic capacitances, output
conductance, cut-off frequency, maximum frequency, GBW, energy and power
consumption are calculated to study the influence of FinFET oxide (SiO2)
layer thickness variation. It is detected from the result and analysis that
the drain current, transconductance, transconductance generation factor,
gain bandwidth and output conductance improve with decrement in oxide layer
thickness whereas, the parasitic capacitances, cut-off frequency and maximum
frequency degrade when there is a reduction in oxide (SiO2) layer thickness.
The parameters like energy and consumed power of FinFET get better when the
oxide (SiO2) layer thickness increases.
Realization of a variable resolution modified semiflash ADC based on bit segmentation scheme
Authors: Ghoshal Pranati , Dey Chanchal , Sen Sunit
Published: April 2022

A modified variable resolution semiflash ADC, based on ?bit segmentation
scheme?, is presented. Its speed and comparator count are identical to a
normal flash ADC. An 8-bit ADC has 256 different bit combinations. Sixteen
consecutive bit combinations from the MSB side - beginning with the first
one, remain unaltered for such an ADC. It continues this way till the last
group of sixteen bits. In the designed circuit, the four MSB and four LSB
bits are determined in the first and second part of the clock. Following the
same logic, the bits in a 16-bit ADC can be found out in only two clock
cycles by employing only fifteen comparators. It implies that a higher
resolution ADC can easily be determined with low power and small die area.
It is tested in P-SIM Professional 9 for an 8-bit ADC and curves drawn to
establish the validity of the proposal.
Transformation of Agricultural Practices and Health Outcomes: An Empirical Investigation of Chronic Kidney Disease of unknown Etiology (CKDu) in Sri Lanka
Authors: Athukoral Wasantha
Published: April 2022

The prevalence of chronic kidney disease of unknown etiology (CKDu) has significantly affected rural families, while creating many socio-economic problems in Sri Lanka. Extreme weather due to climatic change has produced many outcomes in dry zone in the country where more prevalence as well as incidents of CKDu are found. In this context, this study attempts to identify the farmers knowledge and attitudes towards the climate change induced transformation of agricultural practices and then estimate the value of loss in earnings due to being a CKDu patient using the Value of Statistical Life (VSL) approach. The study uses a combination of primary data and secondary data. Results show that farmers’ knowledge and awareness of the impacts of climate change on agricultural practices is satisfactorily high while their contribution to mitigate the impacts of it is not significant. The results of the VSL show that the estimated values of statistical life for the entire sample are approximately Rs. 2.50 million and Rs. 4.33 million under 60 and 70 years of retirement ages respectively. The estimated values of the loss earnings under 60 years of retirement age for 11 districts were Rs. 70.30 billion. The result further reveals that the prevailing situation of the CKDu in these districts has seriously affected the health and well-being of their family members, stress level, consumption as well as education of the kids of the affected families.
Marti´s Ethics in Professional Pedagogical Training
Authors: de la Rosa María del Rosario Yaques
Published: April 2022

The ethical and professional training following Marti´s perspective in professors from the Bachelor of Education in the Philosophy and History Major at University of Granma, Cuba allows the preparation of graduates for the fulfillment of their job with a humanistic essence, with cultural knowledge about the base of a broad general culture. The performance of the students is seen in the increase of the quality of graduates and its social impact is achieved by using a pedagogical strategy in the programs of the disciplines that are taught in the initial training process of the students of the major in order to achieve a high sense of professional pedagogical ethics which allows them to perform efficiently in different contexts of action.
Ethics, Nanotechnology and Elite Sport - The Need For A Precautionary Approach
Authors:   , Evans Robert H.
Published: April 2022

Elite sport is a competitive industry, with athletes continuously striving for innovative ways to gain advantages over their competitors. The increasing impact of sport sciences over recent decades has contributed much to this ethos, and has recently been witnessed in the application of sports engineering, working to integrate new technologies in order to enhance levels of athletic performance and also athlete safety. The application of nanotechnology offers a sport engineer the potential to improve equipment used both in and out of competition. Nevertheless, despite its emerging integration into sports sciences, limited attention has been paid to the ethical impacts this technology may have on elite sport. To address this problem, an eclectic normative approach is pursued, allowing for the range of nanotechnological application to elite sport to be considered, in order to generate critical ethical evaluations in relation to its current and potential use within elite sport. The issues were framed variously through consequentialist and deontological analysis. Three nanotechnological case studies are presented, highlighting potential benefits and disbenefits that nanotechnology may present, and to additionally determine whether, and if so, what, deontologically framed regulatory action were required to govern its use within elite sport. The first case study considered nanotechnology's application to the sport of road cycling; the second considered nanotechnology's application to performance analysis; and the third considered nanotechnology's application to horse race betting. The analysis of the case studies revealed that nanotechnology presents a number of benefits for elite sport, such as improved levels of performance and enhanced safety; but also disbenefits, such as those relating to fairness and corruption. Despite this, it is argued that, at present, nanotechnology does not pose a significant risk to the integrity of sport. But in order to reduce any future risk, the disbenefits should be addressed. A case is consequently argued for the application of a weak version of the Precautionary Principle applied through an original ethical analytical tool, in order to govern the initial integration phase of nanotechnology. The work concludes by outlining more specific regulatory actions that could be taken in order to inform the development of a 'nano' specific regulatory framework, in order to govern nanotechnology's continued long term safe and ethical use within elite sport.
Pemanfaatan Aplikasi Ruang Guru dalam Belajar di Masa Pandemi Covid-19 (Studi Kasus: Lima Orang Siswa SMA di Kota Padang)
Authors: Yanda Wahyu Dwi , Erianjoni Erianjoni
Published: April 2022

The purpose of this study was to determine the use of Ruangguru in learning by high school students during the pandemic. In analyzing this research, the researcher uses the theory of Structural Functionalism which was developed by Robert K. Merton. The informant selection technique used is a purposive sampling technique, namely selecting informants based on the criteria determined by the number of informants 19 people. Collecting data by means of non-participatory observation, in-depth interviews and documentation. The results of research in the field found that there were 3 forms of using the Ruangguru application for high school students in Padang City: (1) Utilization of Ruangguru learning videos and quizzes, (2) Utilization of Question Banks and discussion of Questions, (3) Utilization of Ruangles Online and Roboguru features. Meanwhile, the impact of using the Ruangguru application by five high school students in the city of Padang has increased in value.
Konsep Diri Mahasiswa Dalam Perkuliahan Micro Teaching Prodi Pendidikan Sosiologi FIS UNP
Authors: Junaidi Junaidi , Neviyarni Neviyarni
Published: April 2022

Ideally a student teacher candidate has a good self-concept in order to complete teacher lectures properly. However, several studies reveal the low self-concept of students. This study aims to determine the condition of the self-concept of students of the Sociology Education Study Program, FIS UNP. The research methodology uses a quantitative approach. Data collection using a questionnaire. The collected data were analyzed by statistical percentage techniques. The results of the study revealed that students of the Sociology Education Study Program FIS UNP who took Micro Teaching lectures had good self-concepts. In general, their self-concept is in the high category. They think that they are a complete figure from the physical side. They are confident in their ability to manage emotions. They are also able to follow and complete lecture assignments and are proud of their achievements, including in Micro Teaching lectures. Students feel valued and able to respect their friends and feel comfortable attending classes and in the learning environment.
Pendidikan Karakter Anak Dalam Keluarga (Studi Kasus: Peran Ayah Sebagai Orang Tua Tunggal di Nagari Pasir Talang Kecamatan Sungai Pagu Kabupaten Solok Selatan)
Authors: Sari Mhoren Puspita , Susilawati Nora
Published: April 2022

This study aims to explain the role of fathers as single parents in implementing children's character education in Nagari Pasir Talang, Sungai Pagu District, South Solok Regency. This research uses a qualitative approach with a case study type of research type intrinsic case studies. The results of the study reveal the role of fathers in inculcating character values, namely (1) Fathers educate their children with religious values, which are carried out by fathers by inculcating religious values starting from praying, covering their genitals, and doing good, (2) Fathers guiding children through discipline, namely the application of moral values. character values of self-discipline, discipline of neatness, and discipline of time, (3) Fathers as friends for their children, namely the application of communicative character values through the community and in the family environment, (4) Fathers as mentors for their children, namely the application of independent character values, starting from independently at home and at school.
Pelaksanaan Pembelajaran Sosiologi Jarak Jauh Pada Masa Pandemi Covid-19
Authors: Illahi Ridho , Sylvia Ike
Published: April 2022

Penelitian ini bertujujuan untuk (1) Untuk mengetahui implementasi pelaksanaan BDR yang dilakukan oleh kepala satuan pendidikan dan guru untuk mendukung terselenggaranya proses pembelajaran jarak jauh di SMA Negeri 2 Bukittinggi (2) Untuk mengetahui implementasi pelaksanaan BDR oleh peserta didik pada masa Covid -19 di SMAN 2 Bukittinggi (3). Untuk mengetahui implementasi pelaksanaan BDR oleh orang tua pada masa Covid-19 di SMAN 2 Bukittinggi. Penelitian ini merupakan penelitian kuantitatif. Subjek penelitian ini adalah satuan pendidikan, guru, dan peserta didik kelas XI IPS. Teknik sampling yang digunakan yaitu random sampling, jumlah responden sebanyak 4 satuan pendidikan, 1 guru sosiologi, dan peserta didik sebanyak 69. Instrumen yang digunakan yaitu angket, disusun menggunakan Google Form dan dibagikan ke dalam WhatsApp Group kelas. Hasil penelitian ini menunjukan Implementasi kebijakan BDR yang diterapkan oleh satuan pendidikan dan guru dinyatakan dalam kategori sedang, perserta didik dalam kategori sedang, orang tua dalam kategori sedang sehingga dapat di simpulkan bahwa implementasi pelaksanaan BDR oleh satuan pendidikan, guru, peserta didik, dan orang tua di SMAN 2 Bukittinggi sejalan dengan SE Kemendikbud No 15 tahun 2020 saat PJJ.
Pelaksanaan Penguatan Pendidikan Karakter Pada Masa Pandemi Covid-19 di SMP Negeri 26 Padang
Authors: Fauzan Habib Rafi , Wirdanengsih Wirdanengsih
Published: April 2022

Pendidikan karakter perlu dibelajarkan pada peserta didik di institusi pendidikan, agar dapat menumbuhkan perilaku yang sesuai dengan agama, nilai, dan norma yang dianut. Tujuan dari penelitian ini adalah mendeskripsikan pelaksanaan penguatan pendidikan karakter pada masa pandemi covid 19 di SMPN 26 Padang. Teori yang digunakan pada penelitian, yaitu teori struktural fungsional oleh Talcot Parson. Penelitian ini merupakan penelitian kualitatif dengan tipe studi kasus. Teknik pengumpulan data menggunakanobservasi, wawancara dan dokumentasi. Teknik analisis data yang digunakan adalah model Miles dan Huberman yaitu reduksi data, penyajian data, dan kesimpulan. Hasil penelitian yang diperoleh bahwa pelaksanaan penguatan pendidikan karakter pada masa pandemi covid 19 di SMPN 26 Padang dilaksanakan melalui pengintegrasian nilai-nilai karakter religius, jujur, dan bertanggung jawab. Melalui kegiatan rutin di awal pembelajaran dengan berdoa dan pemberian motivasi, kemudian dilanjutkan dengan pengontrolan keterlaksanaan sikap-sikap religius dan sosial siswa melalui buku agenda.
O DIÁLOGO DE SABERES COMO CONCEPÇÃO NA CONSTRUÇÃO DO CONHECIMENTO E MÉTODO DE TRABALHO NA EDUCAÇÃO DO CAMPO
Authors: Camejo Pereira Viviane , Penha de Paula Adalberto
Published: April 2022

Este estudo discute a relação entre Educação do Campo e o Diálogo de Saberes na produção de conhecimentos a partir da realidade dos sujeitos diante dos seus modos de vida e território. Objetiva apresentar as potencialidades e os desafios do Diálogo de Saberes enquanto concepção de construção de conhecimento e método de trabalho na Educação do Campo. Utiliza abordagem metodológica de natureza documental e bibliográfica. Demonstra a partir dos referencias teóricos e experiências educativas, os limites e possibilidades de construir conhecimentos que possam atender a demanda dos sujeitos e superar visões excludentes e ingênuas presentes na sociedade, herança de perspectivas epistemológicas que silenciaram outras matrizes de produção de conhecimento. Conclui que é possível inserir o Diálogo de Saberes para além de método de trabalho, mas também como concepção na produção de conhecimento na Educação do Campo. Destaca que existem experiências que indicam caminhos possíveis para superar visões simplistas e ingênuas sobre os conhecimentos oriundos dos povos do campo, das águas e das florestas.
Pemberdayaan Ekonomi Pemilik Usaha Pembuatan Nata de Coco, Dusun Jragan II, Kabupaten Bantul
Authors: Maridjo Herry , Mudayen Y.M.V. , Wijayanti Wiwid
Published: April 2022

The purpose of the Science and Technology Implementation of Nata de Coco Business Owners is toincrease the income of the Nata de Coco business owners through education and training on productprocessing as well as on the management of their business. The idea of implementing science andtechnology for Nata de Coco entrepreneurs stemmed from the fact that nata de coco entrepreneurs weregenerally less skilled in processing nata de coco products. The products were less hygienic and were not marketed under their own trademark. The specific target in IbM's activities was the increasing income of the nata de coco businessmen. The method used to achieve this goal was a collaborative method throughvarious trainings, intensive facilitation, hands-on practice, monitoring and evaluation. The outcome ofIbM's program was the production of nata de coco's distinctive, varied, hygienic, and delicious productsso that the sales turnover and the nata de coco craftsmen income continue to increase.
PELATIHAN PEMANFAATAN BENDA-BENDA SEKITAR DAN PERMAINAN UNTUK MEDIA PEMBELAJARAN MIPA DAN IPS DI SD SANJAYA TRITIS PAKEM
Authors: Sumarah Ignatia Esti , Limiansih Kintan , Aprinastuti Christiyanti , Prasetya Andreas Erwin
Published: April 2022

The purpose of this training was to facilitate elementary school teachers in Sanjaya Elementary School Tritis, Pakem so that they were able to provide learning media for Natural and Social Sciences. The learning media was a set of equipment that could be used as learning media to help teachers deliver lessons to the students so that students were motivated to learn. Media that could be used should be helpful for the students to understand the concept of learning, be suitable with the characteristics of the students, and facilitate the students to obtain the learning objectives, as well as appropriate with the learning condition, facilities and time availability. This training was directed in such a way that the teachers in that school became creative in utilizing objects around them to teach Natural and Social Sciences. Games were also used to teach Mathematics.