bluuebunny/crossref_metadata_2025 huggingface dataset:
Anxiety-depressive disorders in obese patients
Authors: Velychko Valentyna , Lahoda Daria , Danylchuk Galina
Published: December 2022

The likelihood of developing major depressive disorder (MDD) and anxiety (T) increases with the number of comorbid metabolic disorders, such as dyslipidemia, insulin resistance, hypertension (AH), and obesity. Research indicates that long-term inflammation caused by reduced physical activity, sedentary behavior, and poor eating habits is necessary for this connection to occur, which in turn can lead to metabolic disorders. The aim of our study was to identify possible anxiety-depressive disorders in obese patients and to investigate the prevalence of such disorders in patients of the Odesa region. According to the research design, 67 obese patients who were treated at the Department of Family Medicine and Polyclinic Therapy of Odesa National Medical University were examined. Patients included in our study were asked to undergo an examination according to a generally accepted algorithm, an anthropometric examination to calculate BMI and determine the content of visceral fat. In addition, patients were asked to complete a series of questionnaires, namely: the physical activity level questionnaire, the HADS Hospital Anxiety and Depression Scale, the Beck Depression Scale, the Generalized Anxiety Disorder Questionnaire (GAD-7), the PHQ-9 questionnaire, and the M.I.N.I. (International Neuropsychiatric Questionnaire). As a result of taking anamnesis, it was established that the vast majority had comorbid diseases in the form of: hypertension - 36 patients (56.72%), type 2 diabetes - 29 patients (43.28%), prediabetes - 15 (22.39%), dyslipidemia was diagnosed in 39 patients (58.21%). Questionnaire M.I.N.I. was used by us to determine the subtype of depressive disorder in our patients. Thus, we found that the most common subtypes were: ADHD (26.87%), depressive disorder with melancholia (16.42%) and dysthymia (17.91%). In our opinion, it is appropriate to use psychological questionnaires in the practice of doctors of various specialties who interact with patients living with obesity. When patients with TDD are identified using diagnostic screening, namely questionnaires, they should be referred for further consultation with a psychotherapist.
Diabetes and stroke
Authors: Mankovsky Boris
Published: December 2022

Acute disorders of cerebral circulation (strokes) are one of the long-known complications of diabetes, which, along with other macrovascular complications, such as myocardial infarction and damage of peripheral arteries are the main cause of death in patients with type 2 diabetes. Strokes are the third leading cause of death in the economically developed countries in Europe and North America. Despite great efforts to reduce the risk of strokes in many developed countries of the world, the increase in life expectancy and the increase in the prevalence of risk factors for the development of stroke (among which diabetes plays a major role) have led to the fact that the probability of having a stroke during one's life has, on the contrary, increased from 22.8% in 1990 to 24.9% in 2016. This review, based on an analysis of the latest available studies, discusses the etiology, pathogenesis, and risk factors for stroke in patients with diabetes mellitus.
Gambaran Pemberian Mp-Asi Pada Bayi Usia 0-6 Bulan Di Wilayah Kerja Puskesmas Lawele Kabupaten Buton
Authors: Akhfar Kurniati , Arfiani Arfiani , Trisnawati Trisnawati
Published: December 2022

Giving MP-ASI too early, namely at the age of less than 6 months is an indicator that the mother has failed to exclusively breastfeed her baby so that it has an impact on the coverage rate of exclusive breastfeeding which is still low. However, in the community, especially mothers of toddlers in Lawele Village, the practice of giving MP-ASI is not timely. The purpose of this study was to determine the description of early complementary feeding in Lawele Village, the working area of Lawele Public Health Center, Buton Regency. This type of research is an observational survey using a descriptive approach. The results of this study were mothers of toddlers who gave MP-ASI to toddlers on time at 26.87% while mothers of toddlers who gave MP-ASI early to toddlers amounted to 73.13%. The results of this study illustrate that the provision of MP-ASI in a timely manner is still very high and often occurs in the community.
Antibacterial activity test of ethanol extract of rambusa leaves (Passiflora foetida L.) against Pseudomonas aeruginosa bacteria
Authors: Sari Wijayanti  , Heriani Heriani , Mustamin Faizal , Syuhada Syuhada
Published: December 2022

One of the medicinal plants in Indonesia is rambutan (Passiflora foetida L.). Some of the chemical substances contained in the leaves of rambusa include alkaloids, flavonoids, steroids, and triterpenoids which have an antibacterial effect. This study aims to determine the activity and concentration of effective antibacterial from the extract of rambutan leaves on the growth of Pseudomonas aeruginosa bacteria. The antibacterial test was carried out using disc diffusion or the Kirby method with test concentrations of 10%, 15%, 20%, and positive control (Ciprofloxacin). The results showed that the antibacterial inhibition of rambutan leaf extract concentrations of 10%, 15%, 20%, and positive control was 2.63 mm, 4.53 mm, 6.05 mm, and 26.72 respectively. The concentration of 20% of rambusa leaf extract showed moderate antibacterial activity with an inhibition zone diameter of 6.05 mm.
The Correlation of Nrf2 rs6721961 Variants with the Risk of Type 2 Diabetes Mellitus and Obesity in Kurdistan of Iraq
Authors: Omar Ahmed Gulshan , Rahimi Zohreh , Shakiba Ebrahim , Nasari Rozita , Khadir Fatemeh , Kohsari Maryam
Published: December 2022

Background: Type 2 diabetes mellitus (T2DM) is an endocrine and metabolic disease that the interaction of genetic background with environmental factors could enhance its risk. The nuclear erythroid-2-related factor 2 (Nrf2) protects cells against oxidative damage and toxicity. Objectives: This study aimed to determine the possible correlation between the Nrf2 gene variants with the risk of T2DM and obesity in the Kurdistan of Iraq. Methods: This study was conducted on 250 individuals categorized into 4 groups: 67 obese T2DM patients (body mass index (BMI) ≥ 30 kg/m2), 65 normal BMI diabetic patients (BMI < 25 kg/m2), 62 obese non-diabetics, and 56 normal BMI non-diabetic individuals. The Nrf2 rs6721961 variants were identified by polymerase chain reaction (PCR) technique followed by digestion with the restriction enzyme of NgoMIV. Results: In the obese T2DM group, the levels of waist, and wrist circumference were significantly more than those of obese non-diabetic controls. Total antioxidant capacity level was not significantly different comparing patients with their controls. The Nrf2 T allele significantly decreased the risk of T2DM in normal BMI patients. In addition, carrying the T allele significantly reduced the risk of obesity. Conclusions: According to the results, significantly higher levels of anthropometric parameters was detected in obese T2DM compared with obese non-diabetic controls. The T allele of Nrf2 decreased T2DM risk among patients with normal BMI and obesity risk among Kurdish residents of Iraq. The findings of our research can be used in the prevention and management of T2DM by improving lifestyle habits.
Reviews and notices
Authors: Ellegård Alvar , Kielow Sabina , Olofsson Arne , Paul Ronald , Tapper Ted , Ankarsjö Magnus , Armini Monica , Pankow Christine , Söhrman Ingmar , Björn Gösta , Kirsch Frank-Michael
Published: December 2022

Includes the following reviews:

p. 238. Alvar Ellegård. Svartvik, J., Engleska - öspråk, världsspråk, trendspråk.

p. 239. Sabina Kielow. Ryan, M., Literary Theory. + Widdowson, P., Literature. The New Critical Idiom.

p. 239-243. Arne Olofsson. Olsson, H., Språket - så fungerar det. Lärobok i allmän grammatik och lingvistik.

p. 243-244. Ronald Paul. Ellegård, A., Jesus, One Hundred Years Before Christ: A Study in Creative Mythology.

p. 244-245. Ted Tapper. Löfgre, H. & Shima, A. (eds), After Consensus: Critical Challende and Social Change in America.

p. 245-246. Magnus Ankarsjö. Mahood, M.M., Playing Bit Parts in Shakespeare.

p. 246-247. Monica Armini. Mikalachki, J., The Legacy of Boadicea: Gender and Nation in Early Modern England.

p. 247-249. Esbjörn Nyström. Packalén, S., Im Spiegel der Literatur. Den tyskspråkiga litteraturen under tolv hundra år.

p. 249-251. Christine Pankow/Ingmar Söhrman. Nordstedts bildordbok. Svenska, Engelska, Tyska, Franska.

p. 251-253. Gösta Björn. Kirsch, F. -M., Stille aber ist Mangelware. Deutschland und die Deutschen in schwedischen Schulbüchern für das Fach Deutsch 1970-1995.

p. 253-254. Frank-Michael Kirsch. Müller Waldeck, G. & Ulrich, R. (Hrsg.), Hans Fallada: Sein Leben in Bildern und Briefen.

p. 254-255. Ingmar Söhrman. Nordstedts spanska ordbok. Spansk - svensk, svensk - spansk.
From the editors
Authors: Bengtsson Sverker
Published: December 2022

-
Marguerite Duras et la piège biographique
Authors: Ahlstedt Eva
Published: December 2022

-
Imaginando un nuevo país: Modernidad y transición en el cine espa¨ñol postfranquista
Authors: Benet Vincente José
Published: December 2022

-
Reviews and notices
Authors: Ankarsjö Magnus , Hellén Anna , Ohlander Sölve , Bowen Rhonwen , Rasinger Sebastian M. , Cregan-Reid Vybarr , Cronquist Ulf , Dentler Sigrid , Andersson Ulrika , Paul Ronald , McQueen Donald , Stålhammar Mall , Thore Petra , Brylla Charlotta , Reeg Ulike , Reeg Ulrike
Published: December 2022

Includes the following reviews:

p. 210. Magnus Ankarsjö. Frykman, E., Shakespearecitat: i sina sammanhang och med kommentarer.

p. 210-211. Anna Hellén. Miller, J. S., Something Completely Different: British Television and American Culture.

p. 211-215. Sölve Ohlander. Crystal, D., The language Revolution.

p. 215-219. Sölve Ohlander. Seiflhofher, B. Controversies in Applied Linguistics.

p. 219-220. Rhonwen Bowen. Thornby, S. Natural Grammar.

p. 220-222. Sebastian M. Rasinger & Vybarr Cregan-Reid. Aikmer, K., Olinder, B., Proceedings from the 8th Nordic Conference on English Studies.

p. 222-223. Ulf Cronquist. Cutting, J., Pragmatics and Discourse. + Field, J. Psycolinguistics. + Jackson, H., Grammar and Vocabulary. + Stockwell, P., Sociolinguistics.

p. 223-226. Sigrid Dentler. Phillipson, R., English-Only-Europe? Challenging Language Policy.

p. 226. Ulrika Andersson. Sell, R. D., Children's Literature as Communication: The ChiLPA project.

p. 226-227. Ronald Paul. Snedeker, G., The Politics of Critical Theory.

p. 227-228. Donald McQueen. Mobärg, M., The Power of the Voice. Famous Poetry and Rhetoric in English.

p. 228. Mall Stålhammar. Baron, I., Language and Culture. Copenhagen Studies in Language 29.

p. 229. Rhonwen Bowen. Stewart, C. & Pointon, G., Word for Word. 'Make the right choice. Get the right meaning'.

p. 229-232. Petra Thore. Gesche, J., Aus zweierlei Perspektiven...Xur Rezeption der Danziger Trilogie von Günter Grass in Polen und Schweden in den Jahren 1958-1990.

p. 232-234. Charlotta Brylla. Arndt, S. & Hornscheidt, A., Afrika und die deutsche Sprache. Ein kritisches Nachslagewerk.

p. 235-237. Ulike Reeg. Thore, P., "wer bist du hier in dieser stadt, in diesem land, in dieser neuen welt". Die Identitätsbalance in der Fremde in ausgewählten Werken der deutschsprachigen Migrantenliteratur.
APPLICATION OF VIRTUAL DESKTOP INFRASTRUCTURE TECHNOLOGIES IN THE INFORMATION INFRASTRUCTURES OF SECURITY AND DEFENSE SECTOR PARTICIPANTS
Authors: Draglyuk O. , Radchenko M. , Korotkov M. , Pavlyuk D.
Published: December 2022

In order to fulfill the tasks of the Strategies of National and Military Security of Ukraine to ensure the introduction of modern information technologies, automation of management processes and digitalization of activities in the defense forces of Ukraine with an appropriate level of information security, which is processed, measures are being taken to bring the existing information infrastructure to modern requirements.
Sosialisasi E-Ktp Dan Pemilih Pemula Di Desa Kedokan Gabus Kabupaten Indramayu
Authors: Sigit Hendriawan  , Wanji Julianto  , Didik Himmawan
Published: December 2022

Kartu Tanda Penduduk elektronik (E-KTP) adalah Kartu Tanda Penduduk yang dibuat secara elektronik, dalam artian baik dari segi fisik maupun penggunannya berfungsi secara komputerisasi. KTP atau Kartu Tanda Penduduk berfungsi untuk menunjukan identitas sebagai warga Negara, seiring berjalannya waktu KTP terus mengalami perubahan hingga pada akhirnya akan muncul KTP berbentuk digital. Adapun E-KTP bias diperlukan untuk keperluan administrasi yang membutuhkan KTP, KK dan semacamnya. Penulis melakukan observasi dan identifikasi masalah untuk penyusunan program KKN. Secara umum permasalahan dari segi Ilmu Pemerintahan yaitu kurangnya Pemahaman Masyarakat Mengenai Pentingnya Memiliki E-KTP dan Pemahaman Kepada Pemilih Pemula yang Baru Berusia 17 Tahun. Berhubungan dengan E-KTP sudah menjadi hal lazim saat menjelang Pemilihan Umum (PEMILU) salah satu topik pembahasan adalah pemilih pemula. Pemilih Pemula adalah warga Negara Indonesia (WNI) yang pada hari pemilihan atau pemungutan suara sudah genap berusia 17 tahun atau lebih. Atau sudah/pernah nikah yang mempunyai hak pilih, dan sebelumnya belum termasuk pemilih karena ketentuan undang-undang pemilu. Pelaksanaan kegiatan dilaksanakan dalam satu kali pertemuan. Yang dimana difokuskan untuk memberi pemahaman kepada pemerintah Desa dan remaja Kedokangabus terkait segala sesuatu tentang E-KTP dan Pemilih Pemula. Dan diakhir kegiatan sosialisasi audience diberi soal posttest untuk mengetahui seberapa jauh menangkap materi yang telah diberikan. Dan juga ada sesi pertanyaan untuk yang belum memahami materi yang sudah diberikan
Male Privilege
Authors: Winnikoff Alan ,   After Dinner Conversation
Published: December 2022

To what extent are allegations of past wrongdoings newsworthy and relevant to voters and political campaigns? In this work of philosophical short story fiction, Mayor Ted is retiring and has requested that Brendon run to replace him. After consulting with his wife, Brendon agrees to run and throws himself into the campaign. As momentums builds, he is contacted by the local newspaper about a former employee who says he attempted to kiss her on a business trip ten years earlier. A few weeks later, one of his son’s teachers comes forward saying he groped her in the parking lot of the school. Brendon denies the allegations, but knows the first allegation is true, while the second was caused by him tripping on an uneven portion of sidewalk. Regardless, his wife decides to temporarily leave him to gather her thoughts, his female campaign manager resigns, and Mayor Ted withdraws his support over the “optics” of the allegations. Brendon limps to election night alone, but, much to his surprise, wins.
The Bargain
Authors: Weiss Thomas J. ,   After Dinner Conversation
Published: December 2022

Can atrocities happen without anyone having alterative choices to stop it? Does superior technology presuppose superior morality? In this work of philosophical short story fiction, the Rigel and the Musca are in a territorial race to the edge of the galaxy. Earth, a habitable planet with an underdeveloped civilization is needed for real estate development so it can support forty billion additional aliens. Vega is the alien real estate developer who has come to earth to offer a choice; support your colonization, and have technology shared with you prior to alien arrival, or fight us, and face your complete extinction at the hands of superior technology prior to alien arrival. Left with no good choices, humanity decides to fight.
The Social Ontology of Alain Badiou’s Being and Event
Authors: Kim Min Seong ,   Romanian Academy - Iasi Branch
Published: December 2022

The innovation of Alain Badiou’s theory of change, which has attracted a great amount of attention from scholars working in disciplines across humanities, social sciences, and art over the past two decades, cannot be appreciated independently of the account of situations prior to an event’s irruption, namely, the order of being that is conceived using modern set theory in his treatise on general ontology. Retracing the meticulous systematicity with which pre-evental situations are conceived in Being and Event, this paper offers a reconstruction of Badiou’s general ontology that points toward the potential therein for articulating an account of structures and situations that may be qualified as social.
ANALISIS PENGARUH KUALITAS PRODUK, KEPUTUSAN PEMBELIAN, KUALITAS PELAYANAN TERHADAP KEPUASAN PELANGGAN DENGAN HARGA SEBAGAI VARIABEL INTERVENING
Authors: Suwito Hendry , Setyowati Rr. Dyah Eko
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh kualitas produk, keputusan pembelian, kualitas pelayanan terhadap kepuasan pelanggan dengan harga sebagai variabel intervening. Sampel penelitian ini sebanyak 125 responden. Metode pengolahan data memakai analisis jalur dengan menggunakan teknik SEM AMOS. Dari hasil penelitian dengan pengujian hipotesis didapat hasil sebagai berikut: Ha1 diterima, sehingga dapat dikatakan variabel kualitas produk mempengaruhi variabel harga. Ha2 diterima, sehingga dapat dikatakan variabel keputusan pembelian mempengaruhi variabel harga. Ha3 diterima, sehingga dapat dikatakan variabel kualitas pelayanan mempengaruhi variabel harga. Ha4 diterima, sehingga dapat dikatakan variabel kualitas produk mempengaruhi variabel kepuasan pelanggan. Ha5 diterima, sehingga dapat dikatakan variabel keputusan pembelian mempengaruhi variabel kepuasan pelanggan. Ha6 diterima, sehingga dapat dikatakan variabel kualitas pelayanan mempengaruhi variabel kepuasan pelanggan. Ha7 diterima, sehingga dapat dikatakan variabel harga mempengaruhi kepuasan pelanggan. Ha8 diterima, sehingga dapat dikatakan variabel kualitas produk mempengaruhi secara tidak langsung terhadap kepuasan pelanggan. Ha9 diterima, sehingga dapat dikatakan variabel keputusan pembelian mempengaruhi secara tidak langsung terhadap kepuasan pelanggan. Ha10 diterima, sehingga dapat dikatakan variabel kualitas pelayanan mempengaruhi secara tidak langsung terhadap kepuasan pelanggan.
relação família e escola na visão de professores após curso de formação continuada
Authors: Garcia Luciana Marolla , Cia Fabiana , Capellini Vera Lúcia Messias Fialho
Published: December 2022

O contato entre família e escola é de suma importância para a inclusão escolar dos alunos. A participação da família no processo de escolarização de alunos com deficiência intelectual é fundamental para o desenvolvimento do aluno. Sendo assim, para atender a temática da relação família e escola, foi realizado um estudo com objetivo de avaliar a opinião de professores sobre a relação entre família e escola após a realização de um curso de formação continuada. Para o método, foi desenvolvido e enviado um questionário (online) em forma de convite para 147 professores, concluintes de um curso de formação continuada de práticas pedagógicas inclusivas para a área da deficiência intelectual. O questionário foi estruturado contendo nove questões objetivas e uma questão aberta. Como resultado, infere-se que compreenderam a importância dessa relação e que tanto o relacionamento com os pais dos alunos, quanto as questões relativas as inclusões, são de responsabilidade de todos, além de ampliaram sua visão sobre a questão das parcerias.
Análise das postagens em torno de surdez e educação realizadas na plataforma Youtube®, durante o período de pandemia decorrente da COVID-19
Authors: Mainieri Claudia Mara Padilha , Camargo Isabela Jordão de , Santos Israel Bispo dos , Guarinello Ana Cristina
Published: December 2022

O COVID-19 provocou o distanciamento social em caráter de urgência o que fez com que a internet, tornasse-se um espaço de possibilidades de informação e interação. Dessa forma, o presente artigo tem como objetivo analisar as postagens de vídeos em torno da surdez, educação e pandemia, no que se refere às dificuldades enfrentadas e as tendências que surgiram nesta área a partir deste período. A metodologia utilizada foi de cunho qualitativo e quantitativo a partir de análise de vídeos postados no YouTube relacionados a surdez, pandemia e educação, no período de março a novembro de 2020. Para a realização da análise, os vídeos foram categorizados em dois eixos: 1) Dificuldades em torno da surdez e 2) Tendências em torno da surdez apresentadas nos vídeos a partir da pandemia. Observou-se na análise de resultados que dos 24 vídeos analisados, a grande maioria apresentou como tema de discussão as dificuldades na acessibilidade linguística dos surdos, as quais já ocorriam antes da pandemia e se agravaram neste período. Além das dificuldades, alguns vídeos focaram-se nas tendências e novidades a partir da pandemia, as quais focaram-se na acessibilidade educacional e linguística de pessoas surdas. Conclui-se que a maior dificuldade apresentada pelos surdos durante esse período foi a falta de acessibilidade linguística, especialmente, com relação ao uso mais efetivo das novas tecnologias. Novas pesquisas que discutam essas dificuldades e tendências são necessárias, a fim de que a acessibilidade das pessoas surdas possa ocorrer continuadamente, levando em conta suas diferenças e possibilidades.
Formação inicial de pedagogos(as) numa perspectiva inclusiva: um panorama de pesquisas brasileiras
Authors: Borges Fabio Alexandre , Alves Lucas Henrique Barbosa
Published: December 2022

Este estudo configura-se como uma pesquisa bibliográfica cujo objetivo foi investigar que aspectos são evidenciados em pesquisas brasileiras que abordam a inclusão educacional em cursos de formação inicial em Pedagogia. Para a produção dos dados, optou-se por periódicos científicos brasileiros com avaliação Qualis Capes A1, A2 e B1 (quadriênio 2013-2016) nas áreas de Ensino ou Educação. Na seleção dos artigos, considerou-se resultados de pesquisas oriundas do contexto brasileiro publicadas entre 2008 e 2019. A seleção dos artigos compreendeu duas etapas: na primeira, foram utilizadas como busca as palavras “inclusão” e “inclusiva” nos títulos dos artigos, que resultou em 217 textos; na segunda, optou-se por nova filtragem, com a escolha somente de textos com as palavras “pedagogia” ou “formação inicial” no título, que resultou em 16 artigos. Desses, 10 foram considerados para a análise, por trazerem elementos relacionados ao objetivo desse texto. Para a análise do corpus da pesquisa, foram utilizados elementos da Análise de Conteúdo, com a definição das seguintes unidades de análise: Práticas formativas no Ensino Superior e os aspectos da Educação Especial na perspectiva inclusiva; Análises dos aspectos da Educação Especial na perspectiva inclusiva a partir dos PPC’s; e Movimento de mudanças na implantação de documentos que norteiam os cursos sob aspectos da Educação Especial na perspectiva inclusiva. Destaca-se, como resultados, o advento da inclusão educacional tensionando cursos em suas reestruturações curriculares, e em sendo essa demanda algo recente, há que se manter um diálogo contínuo e coletivo acerca de como abordarmos a inclusão em cursos de Pedagogia.
Brazilian cohort results of the PRECONNECT study: safety and efficacy of trifluridine/tipiracil in metastatic colorectal cancer
Authors: Mello Celso Abdon Lopes de , Cruz Felipe Melo , Vieira Fernando Meton de Alencar Camara , Azambuja Alan Arrieira , Leite Luiz A Senna , Mardegan Luciana , Gil Andreia , Vidot Loïck , Coutinho Anelisa
Published: December 2022

PRECONNECT is a multicenter study demonstrating the efficacy and tolerability of trifluridine/tipiracil in adult patients with histologically confirmed adenocarcinoma of the colon or rectum and pretreated metastatic lesions. The current article describes the characteristics and outcomes of the Brazilian cohort of patients who underwent trifluridine/tipiracil therapy within PRECONNECT. Brazilian patients (n=55) received oral trifluridine/tipiracil 35mg/m2 twice daily on days 1-5 and 8-12 of each 28-day cycle. The primary endpoint was safety including time to ECOG (Eastern Cooperative Oncology Group) PS (performance status) deterioration, and the secondary endpoints included progression-free survival (PFS) and quality of life (QoL). Baseline characteristics showed only 34.5% of patients underwent ≥3 lines of treatment, 29.1% presented ≥3 metastatic sites and 52.7% showed an ECOG PS of 0. The disease control rate (DCR) was 32.0% and 28.6% in patients with one and two metastatic sites, respectively, the median PFS was 3.0 months (95%CI: 2.5-3.4), and the time to ECOG PS deterioration (≥2) was 5.4 months. Drug-related treatment-emergent adverse events (TEAE) were observed at least once in 87.3% of patients, and the most common (≥40% of patients) hematological TEAEs were neutropenia and anemia; there was no febrile neutropenia case. The shorter time to ECOG PS deterioration showed in the Brazilian subset of patients is likely due to late diagnosis setting compared to the global population, despite that trifluridine/tipiracil showed good DCR results, including patients with two metastatic sites. In conclusion, safety and efficacy results provide confidence in routine practice use and are in line with the PRECONNECT study
Subgroup analysis of Brazilian participants of a medical leadership competencies instrument: a cross-sectional survey study of the Latin American Cooperative Oncology Group (LACOG) and the Academy of Leadership Sciences Switzerland (ALSS)
Authors: Mano Max Senna , Jesus Rafaela Gomes , Barrios Carlos Henrique Escosteguy , Fernandes Wanessa Cassemiro , Oliveira Leandro Jonata de Carvalho , Vieira Abna Faustina Sousa , Clara Renan Orsati , Frasson Antônio Luiz , Marta Gustavo Nader , Simon Sérgio Daniel , Villarreal-Garza Cynthia , Werutsky Gustavo , Çitaku Fadil
Published: December 2022

Introduction: We previously published the results of a medical leadership (ML) competencies instrument applied to Latin-American (LA) physicians with a leadership position, which disclosed meaningful differences in the valuation of specific ML competencies by LA physicians as compared to a similar survey applied to healthcare professionals from North America and Europe (NA/EU). Because the most pronounced differences in the responses were in terms of country of medical practice, we felt that an analysis focused on the Brazilian participants (a culturally more homogeneous population) could provide further insights into understanding other subgroup differences.

Objectives: We aimed to: 1) compare the responses from the Brazilian participants with those of the NA/EU survey and 2) perform subgroup analyses within the Brazilian participants. Design and Setting: Cross-sectional survey study applied only once.

Material and Methods: Between November 13th and December 12th, 2018, we collected 217 responses. Results: There were (n=135/63%) Brazilian participants. The valuation of a set of ML competencies by Brazilian physician-leaders roughly match those of the main study (task management remaining the most valued set of competencies versus 3rd in the NA/EU survey). However, significant differences in the responses were seen in some subgroups, especially in terms of the impact of seniority (which no longer appears to affect the responses) and gender (with women no longer placing a higher value on innovation competencies).

Conclusion: This analysis reinforces the existence of significant cultural differences within the LA participants, and that these cultural variations can significantly affect the valuation of specific ML competencies.
How conflicted are farmers about meat? livestock farmers’ attachment to their animals and attitudes about meat
Authors: Crawshaw Chloe , Piazza Jared
Published: December 2022

Livestock farmers depend on animal slaughter for their livelihood while also being responsible for their animals’ welfare. This study explored how farmers psychologically manage this ambivalent relationship with their animals. Seventy-two meat-eating livestock farmers participated, as well as 99 meat-eating and 103 meat-avoiding, non-farmer pet owners, living in the UK. Participants were assessed on their attachments to their pets and farmed animals (the latter for farmers only), the perceived cognitive abilities of cows (relative to dogs), their degree of conflict about meat and the perception of viable alternatives to meat. Farmers exhibited the lowest levels of meat conflict and perception of alternatives to meat. They were less attached to their farmed animals than their companion animals, and farmed animal detachment correlated, albeit weakly, with lower conflict. Farmers did not attribute more mental capacities to cows than non-farmers. Overall, denial of mind to cows and denial of alternatives related to lower levels of meat conflict. These findings suggest that farmers do not experience much conflict about meat and this lack of conflict is sustained through a combination of dissonance-avoidance strategies, including detachment, denial of mind, and denial of choice.
Development of Core Competency Scale for clinical nursing student educators
Authors: Park Hyun Sook , Choi Eun Hee , Kim Gyung Duck , Kim Young Hee , Jeon Mi Yang , Hwang Hyenam
Published: December 2022

Purpose: This study aimed to develop a Core Competency Scale for clinical nursing student educators.Methods: In this study, we constructed a conceptual framework, selected initial items, verified the content validity, conducted two rounds of Delphi expert consultation, selected secondary and tertiary items, and extracted the final items. The study included 242 clinical educators for nursing students. Item analysis, factor analysis, criterion validity, and internal consistency were used for the data analyses.Results: For the final scale, 35 items were selected and 5 factors were categorized, which together explain 61.7% of the total variance. The factors were education and evaluation, research and cooperation, ethical/legal principles, presenting leadership, and clinical practice. The scores for the scale significantly correlated with the teaching efficacy scale for clinical nursing instructors. The Cronbach’s alpha coefficient for the 35 items was .96.Conclusion: The findings of this study demonstrated that the core competency scale has good validity and reliability. This scale can be used to assess the competency of clinical educators for nursing students; hence, it will help in evaluating the relationship between the skills of clinical educators for nursing students and the self-efficacy of those students.
The validity and reliability of the Korean version of the General Attitudes towards Artificial Intelligence Scale for nursing students
Authors: Seo Yon Hee , Ahn Jung-Won
Published: December 2022

Purpose: The aim of the study was to verify the validity and reliability of the Korean version of the General Attitudes towards Artificial Intelligence Scale (GAAIS-K) for nursing students.Methods: Data from 235 participants were collected from April 12 to April 26, 2022. A total of 230 participants’ data were analyzed. The data were analyzed for content, discriminant, known-groups, and construct validity using content validity index, correlation coefficient, and confirmatory factor analyses. The reliability of the GAAIS-K was examined using internal consistency and test-retest analyses.Results: The expert-rated content validity index was ≥.80. The sub-scales of the GAAIS-K were moderately correlated with attitude toward accepting technology, indicative of its discriminant validity. The male students’ positive attitude score was significantly higher than that of the female students, satisfying the known-groups validity. Cronbach’s α for the scale was .86 (positive) and .74 (negative), and the intra-class correlation coefficient for the two-week test-retest reliability was .86 (positive) and .60 (negative). The scores for positive and negative attitudes were 3.68±0.46 and 3.05±0.55.Conclusion: This study shows that the GAAIS-K is a valid and reliable instrument for assessing nursing students. Additional research is recommended to continue the evaluation of the GAAIS-K with a focus on healthcare settings.
Educational goals and objectives of nursing education programs: Topic modeling
Authors: Park Eun-Jun , Ok Jong Sun , Park Chan Sook
Published: December 2022

Purpose: This study aimed to understand the keywords and major topics of the educational goals and objectives of nursing educational institutions in South Korea.Methods: From May 10 to May 20, 2022, the educational goals and objectives of all 201 nursing educational institutions in South Korea were collected. Using the NetMiner program, degree and degree centrality, semantic structure, and topic modeling were analyzed.Results: The top keywords and semantic structures of educational goals included ‘respect for human (life)-spirit-science-based on, global-competency-professional nurse-nursing personnel-training, professional-science-knowledge-skills, and patients-therapeutic care-relationship.’ The educational goals’ major topics were clients well-being based on science and respect for human life, a practicing nurse with capabilities and spirit, fostering a nursing personnel with creativity and professionalism, and training of global nurses. The top keywords and semantic structures of the educational objectives included ‘holistic care-nursing-research-action-capability, critical thinking-health-problem solving-capability, and efficiency-communication-collaboration-capability.’ The educational objectives’ major topics were ‘nursing professionalism, communication and problem-solving capability; a change of healthcare environments and a progress of nursing practices; fostering professional nurses with creativity and global capability; and clients’ health and nursing practice.’Conclusion: Educational goals in nursing presented specific nursing values and concepts, such as respect for human life, therapeutic care relationships, and the promotion of well-being. Educational objectives in nursing presented the competencies of nurses as defined by the Korean Accreditation Board of Nursing Education (KABONE). Recently, the KABONE announced new program outcomes and competencies, which will require the revision of educational goals. To achieve those educational objectives, it is suggested that the expected level of competencies be clearly defined for nursing graduates.
Influences of positive psychological capital, interpersonal competence, and character on caring efficiency in nursing students
Authors: Kwon Suhye , Hong Minjoo , Ryu Min , Shin Haeyun
Published: December 2022

Purpose: The purpose of this study was to identify the factors influencing nursing students’ caring efficiency.Methods: This study included 212 nursing students from three University nursing departments in Busan metropolitan city. Data were collected from September 1 to September 29, 2021, using self-report questionnaires. For data analysis, descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficient, and hierarchical multiple regression analyses were conducted with SPSS version 24.0.Results: Positive psychological capital and interpersonal competence on the relationship and character of nursing students were positively correlated with caring efficiency. The variables affecting the caring efficiency of the subjects were character (β=.60, p<.001), amount of participation in a character development program (5 times or more) (β=.16, p=.023), levels of stress (moderate β=.13, p=.037; low β=.15, p=.015), motivation to apply to a nursing program (β=.12, p=.024), and volunteer experience (β=.11, p=.038). The total explanatory power of the variables was 50.0% (F=14.69, p<.001).Conclusion: Character was one of the biggest influential factors on caring efficiency. In order to improve nursing students' caring efficiency, above all, it is necessary to make efforts to raise the level of individual character.
Factors influencing nursing students’ care intentions toward emerging infectious diseases patients: A descriptive-predictive study
Authors: Park Seungmi , Jang Insun , Yu Soo-Young
Published: December 2022

Purpose: As coronavirus disease 2019 (COVID-19) and other emerging infectious diseases continue to threaten health security, a strategy is required to increase nursing students’ care intention for patients with such diseases. This study aimed to identify factors influencing Korean nursing students’ care intentions in regard to patients with emerging infectious diseases.Methods: The care intention, COVID-19 knowledge level, ethical sensitivity, beliefs, attitudes toward the care intention, subjective norms, and perceived behavioral control were investigated using the theory of planned behavior. An online survey was completed from December 2020 to January 2021 by 227 nursing students who had complete a clinical practicum. Descriptive statistics, correlation, and hierarchical regression analyses were conducted on the data.Results: The care intention was higher in men than in women nursing students and in junior than in senior students. Behavioral and normative beliefs, attitude toward the behavior, and perceived behavioral control significantly predicted care intention. Ethical sensitivity increased the predictability of nursing students’ care intentions for emerging infectious disease patients.Conclusion: The theory of planned behavior predicted nursing students’ care intentions for emerging infectious diseases. Therefore, an experience-based response program on emerging infectious diseases is required for nursing students.
What Is Happening to This Patient With a Rare Leukemia?
Authors: Ndje, MS, MBA, APRN, FNP-C Amandine , B. Broadway-Duren, PhD, DNP, APRN, FNP-BC Jacqueline
Published: December 2022

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare cancer with primary sites in the skin and bone marrow and secondary sites in the lymph nodes, spleen, and central nervous system. First described in the 1990s, these cells express a CD123 antigen hinting at a plasmacytoid dendritic cell origin. A CD123-directed cytotoxin called SL-401 was approved by the US Food and Drug Administration and the European Medicines Agency. During BPDCN treatment, a life-threatening syndrome can occur, but early awareness leads to positive patient outcomes.
Social Mobility Patterns Among Black Emerging Adults in Suffolk County, MA
Authors: Motley Robert , Williamson Eric , Motley Jamie , Siddiqi Rebekah
Published: December 2022

This study provides insight into the social mobility patterns of Black emerging adults 22 to 29 years of age in Suffolk County, Massachusetts. This research specifically looks at educational attainment, employment, and income as factors for upward social mobility.
Nota aclaratoria a las tres cartas manuscritas de Robbe-Grillet a José María Fernández Cardo
Authors: Fernández Cardo José María
Published: December 2022

ON THREE HANDWRITTEN LETTERS FROM ROBBE-GRILLET TO JOSÉ MARÍA FERNÁNDEZ CARDO

Notas a cartas manuscritas

À propos des lettres manuscrites
INHERENT COMMITMENT TO SUSTAINABILITY AMONG BASQUE ADVENTURE TOURISM ENTERPRISES DESPITE CRISIS
Authors: Fernández-Villarán Asunción , Uresandi Nagore
Published: December 2022

Existing literature in the field of sustainable tourism highlights a number of barriers that impede the implementation of practices in this area. However, few studies have addressed the case of adventure tourism. Adopting a case study approach, this paper discusses a number of drivers of success identified by adventure tourism enterprise owners in Basque Country to contribute to the implementation of sustainable tourism practices. Adventure tourism has important social, economic, and environmental impacts on sustainability. The study focuses on learning how sustainable practices have changed in these companies because of the COVID-19 crisis.

La literatura existente en el campo del turismo sostenible destaca una serie de barreras que dificultan la implementación de prácticas sostenibles en esta área. Sin embargo, encontramos escasos estudios que se centren en el caso del turismo activo. A través de un estudio de caso, este trabajo analiza un número de impulsores o facilitadores de éxito, identificados por los propietarios de empresas de turismo activo en el País Vasco, que contribuyen a la implementación de prácticas sostenibles. El turismo activo tiene importantes impactos en la sostenibilidad económica, social y medioambiental. El estudio se centra en conocer cómo han cambiado las prácticas sostenibles en estas empresas debido a una crisis como la del COVID-19.
INFORMATION AND COMMUNICATION TECHNOLOGIES (ICT) AS A TOOL FOR SUSTAINABLE TOURISM MANAGEMENT: A BIBLIOMETRIC ANALYSIS
Authors: Vidal-Serrano Laura , Rodríguez-Antón José Miguel , Rubio-Andrada Luis , Narbona-Reina Beatriz
Published: December 2022

The tourism sector has experienced a steady growth in the last decades, becoming one of the key sectors for the development of countries. However, the pandemic caused by COVID-19 brought about an unprecedented social, economic and health crisis that has forced a change in the way tourism is conducted. This article presents a comprehensive bibliometric analysis of different Information and Communication Technologies’ uses in sustainable tourism management to study the literature and serve as a roadmap for future research in this field.

El sector turismo ha experimentado un crecimiento constante en las últimas décadas, convirtiéndose en uno de los sectores clave para el desarrollo de los países. Sin embargo, la pandemia ocasionada por la COVID-19 ha traído consigo una crisis social, económica y sanitaria sin precedentes que ha forzado un cambio en la forma de hacer turismo. Este artículo presenta un análisis bibliométrico exhaustivo sobre el uso de las TIC como herramientas de gestión turística sostenible con la finalidad de conocer la producción académica y servir como hoja de ruta para futuras investigaciones en este campo.
MADRID IN NON-SPANISH SPEAKING CINEMA (1955-2020): FILM LOCATIONS AND THE TOURIST GAZE
Authors: Aertsen Víctor , Gámir Agustín , Manuel Carlos
Published: December 2022

The article investigates the image of the city of Madrid and its relationship with the tourist gaze in non-Spanish-speaking films shot between 1955 and 2020. For the research, 606 clips from a selection of 40 feature films have been geolocated and analyzed. The study shows the distribution of filming locations in different areas of the city, with relevant contrasts between the historic center of Madrid and other areas such as the Ensanche and the peripheral areas. Finally, it reflects on the relationship between the most frequent locations and the commonly recognized tourist landmarks in Madrid.

El artículo investiga la imagen de la ciudad de Madrid y su relación con la mirada turística en películas de habla no española rodadas entre 1955 y 2020. Para ello se han geolocalizado y analizado 606 clips de una selección de 40 largometrajes. El estudio evidencia la distribución de localizaciones de rodaje en las diferentes áreas de la ciudad, con contrastes relevantes entre el centro histórico de Madrid y otros ámbitos como el Ensanche y las periferias. Finalmente, se reflexiona sobre la relación existente entre las localizaciones más frecuentes y los enclaves turísticos comúnmente reconocidos en Madrid.
ECOMMERCE WEB CONTENT ADOPTION MODEL (EWCAM): AN INTEGRATED TOOL FOR WCA AND EMICA MODELS FOR THE TOURISM INDUSTRY
Authors: Ramón-Cardona José , Daries Natalia , Cristóbal Fransi Eduard , Serra-Cantallops Antoni
Published: December 2022

The aim of this work is to develop a model that synthesizes the properties of WCA (Web Content Analysis) and eMICA (extended Model of Internet Commerce Adoption). The development was based on a multivariate analysis (Principal Component Analysis and Structural Equation Models) carried out on a real sample of companies, specifically ski resorts. The resulting model, e-Commerce Web Content Adoption Model (eWCAM) is a modification of the WCA, which has properties attributed to eMICA. This makes it much easier to check whether websites of Tourism Industry have the right information and are mature enough for e-commerce.

El objetivo de este trabajo es desarrollar un modelo que sintetice las propiedades de WCA (Web Content Analysis) y eMICA (extended Model of Internet Commerce Adoption). Su desarrollo se ha basado en un análisis multivariante (Análisis de Componentes Principales y Modelos de Ecuaciones Estructurales) realizado sobre una muestra real de empresas, concretamente de estaciones de esquí. El modelo resultante, e-Commerce Web Content Adoption Model (eWCAM) es una modificación del WCA, que tiene propiedades atribuidas al eMICA. Esto facilita la comprobación de si los sitios web de la industria turística tienen la información adecuada y están suficientemente maduros para el comercio electrónico.
PERCEPTION OF AND MOTIVATION FOR ATTENDING BULLFIGHTS: A COMPARATIVE ANALYSIS OF TOURISTS AND RESIDENTS
Authors: Cerezo López José María , Castillo Canalejo Ana María , Mora Márquez César
Published: December 2022

This article analyses the link between bullfighting and tourism, and the motivations and satisfaction of the attendees. It carries out a comparative analysis of tourist profiles and their motives for attending or not a bullfight. The aim is to analyse the variables influencing the satisfaction of attendees at bullfights. The results reveal significant differences between residents and tourists on the level of satisfaction, with higher levels for higher-income attendees, and in demographic variables, the motivation for attending bullfights and feelings about the life of the animal.

Se analiza el vínculo entre la tauromaquia y el turismo, las motivaciones y la satisfacción de los asistentes. Se realiza un análisis comparativo de los perfiles de los turistas y sus motivos para asistir o no a una corrida de toros. El objetivo es analizar las variables que influyen en la satisfacción de los asistentes a las corridas. Los resultados revelan diferencias significativas entre residentes y turistas en el nivel de satisfacción, siendo más alto para los de mayor renta, y en las variables demográficas, la motivación y los sentimientos sobre la vida del animal.