bluuebunny/crossref_metadata_2025 huggingface dataset:
Bone Health and Its Positive Relationships with Body Composition in Malaysian Schoolchildren: Findings from a Cross-Sectional Study
Authors: Koo Hui Chin , Lim Geok Pei , Kaur Satvinder , Chan Kai Quin , Chan Keh En , Chung Casey , Wong Michelle , Danaselvam Ugunesh
Published: July 2021

Background: Optimal bone health is vital in children to prevent osteoporosis later in life, and body composition plays a crucial role in it. However, the literature reports contradictory results when considering the relationship between body composition and bone health in children. This study aimed to examine the bone health and its relationship with body composition in Malaysian schoolchildren. Methods: In this cross sectional study, body composition data (weight, height, body fat percentage [% fat], fat mass, fat free mass, visceral fat, waist circumference [WC] and body mass index-for-age [BMI z-score]) and bone health data (Z-score and broadband ultrasound attenuation [BUA]) were collected from 415 schoolchildren aged 9–12 years, cluster sampled from randomly selected primary schools in Kuala Lumpur, Malaysia. Results: Girls generally had significantly higher height, body fat percentage, fat mass, visceral fat and Z-score as compared to boys. A steady increase of the mean BUA value was observed with increasing age in both sexes. The mean BUA value of the present study across the population was significantly higher than that of schoolchildren from Nigeria (p < 0.001), Colombia (p < 0.001) and Spain (p = 0.002). Significant positive correlations were found between all the body composition variables and bone outcome variables across the population. Further, BUA was significantly correlated with weight (β = 0.172; p = 0.001), height (β = 0.299; p < 0.001), % fat (β = 0.131; p = 0.007), fat mass (β = 0.130; p = 0.007), fat free mass (β = 0.209; p < 0.001), visceral fat (β = 0.127, p = 0.008), WC (β = 0.165; p = 0.001) and BMI z-score (β = 0.162; p = 0.001), after controlling for sex, age and ethnicity. Similarly, after confounders adjusted, Z-score was significantly predicted by weight (β = 0.160; p = 0.001), height (β = 0.310; p < 0.001), % fat (β = 0.104; p = 0.032), fat mass (β = 0.107; p = 0.026), fat free mass (β = 0.218; p < 0.001), visceral fat (β = 0.107, p = 0.026), WC (β = 0.145; p = 0.002) and BMI z-score (β = 0.150; p = 0.002). Conclusions: Our findings have revealed that body composition variables were positive correlated with bone outcome variables, suggesting that adipose tissue acts to stimulate bone growth. Further clinical and molecular studies in the future is recommended to fully illustrate the complex interactions between adiposity and bone health.
Implementation of a Hybrid Educational Program between the Model of Personal and Social Responsibility (TPSR) and the Teaching Games for Understanding (TGfU) in Physical Education and Its Effects on Health: An Approach Based on Mixed Methods
Authors: García-Castejón Gregorio , Camerino Oleguer , Castañer Marta , Manzano-Sánchez David , Jiménez-Parra José Francisco , Valero-Valenzuela Alfonso
Published: July 2021

The present study investigates the effect of an educational program hybridized between the Model of Personal and Social Responsibility (TPSR) and the Teaching Games for Understanding (TGfU) in physical education classes on the health and psychosocial variables of students, as well as knowing the advantages and disadvantages of its implementation by teachers. The applied program lasted 11 weeks in two Secondary Education centers with a total of four teachers (two in the experimental group and two in the control group) and 99 students (55 from the control group and 44 from the experimental group). We use research methodology Mixed Methods with a quasi-experimental design, where students completed a questionnaire before and after the educational program and teachers were interviewed at the end of the intervention. The results of the questionnaires indicate significant improvements in the experimental group over time in terms of the intention to be physically active, as well as in autonomous motivation, the self-determination index, the index of psychological mediators, personal and social responsibility, and enjoyment. Moreover, the interviews show positive opinions regarding the organizational capacity of the session using this methodology and the interest of teachers in continuing to apply it in the future, as well as the need for initial and ongoing training for proper implementation. In conclusion, the hybridization between the TPSR and TGfU model is presented as an effective alternative to be applied in the educational context with the aim of improving young peoples’ intention to be physically active and psychological variables, such as motivation, responsibility, and enjoyment, in physical education classes.
Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential Pathogenesis
Authors: McGrowder Donovan A. , Miller Fabian , Anderson Cross Melisa , Anderson-Jackson Lennox , Bryan Sophia , Dilworth Lowell
Published: July 2021

Globally, millions of persons have contracted the coronavirus disease 2019 (COVID-19) over the past several months, resulting in significant mortality. Health care systems are negatively impacted including the care of individuals with cancers and other chronic diseases such as chronic active hepatitis, cirrhosis and hepatocellular carcinoma. There are various probable pathogenic mechanisms that have been presented to account for liver injury in COVID-19 patients such as hepatotoxicity cause by therapeutic drugs, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of the bile duct cells and hepatocytes, hypoxia and systemic inflammatory response. Liver biochemistry tests such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) are deranged in COVID-19 patients with liver injury. Hepatocellular damage results in the elevation of serum AST and ALT levels in early onset disease while a cholestatic pattern that develops as the disease progress causes higher levels of ALP, GGT, direct and total bilirubin. These liver biochemistry tests are prognostic markers of disease severity and should be carefully monitored in COVID-19 patients. We conducted a systematic review of abnormal liver biochemistry tests in COVID-19 and the possible pathogenesis involved. Significant findings regarding the severity, hepatocellular pattern, incidence and related clinical outcomes in COVID-19 patients are highlighted.
The Effect of Extra Educational Elements on the Confidence of Undergraduate Dental Students Learning to Administer Local Anaesthesia
Authors: Sjöström Mats , Brundin Malin
Published: July 2021

Local anaesthesia is taught early in the practical part of dental programs. However, dental students express uncertainty and concern before their practical training in local anaesthesia. The aim of this study was to evaluate how extra educational elements in the teaching of local anaesthesia affect students’ confidence using local anaesthesia. The students were divided into three groups (A, B and C). Group A received the same education that was used the previous year (i.e., four hours of theoretical lectures followed by four hours of practical exercises performed on a fellow student). Group B did their practical training on fellow students in groups of three, with each student taking turns performing, receiving and observing the procedure. Group C received training using an anatomically correct model before their practical training on a fellow student. After each training step, the students completed a questionnaire about their confidence administering local anaesthesia. The students experienced a significant increase in confidence after each educational step. Combining theory and practical instruction, including the use of anatomically correct models and peer instruction, improved students’ confidence in administering local anaesthesia. The greatest increase in confidence was in the students placed in groups of three where each student performed, received and observed the procedure.
Application of X-Shaped CFRP Ropes for Structural Upgrading of Reinforced Concrete Beam–Column Joints under Cyclic Loading–Experimental Study
Authors: Golias Emmanouil , Zapris Adamantis G. , Kytinou Violetta K. , Osman Mourhat , Koumtzis Michail , Siapera Danai , Chalioris Constantin E. , Karayannis Chris G.
Published: July 2021

The effectiveness of externally applied fiber-reinforced polymer (FRP) ropes made of carbon fibers in X-shape formation and in both sides of the joint area of reinforced concrete (RC) beam–column connections is experimentally investigated. Six full-scale exterior RC beam–column joint specimens are tested under reverse cyclic deformation. Three of them have been strengthened using carbon FRP (CFRP) ropes that have been placed diagonally in the joint as additional, near surface-mounted reinforcements against shear. Full hysteretic curves, maximum applied load capacity, damage modes, stiffness and energy dissipation values per each loading step are presented and compared. Test results indicated that joint sub assemblages with X-shaped CFRP ropes exhibited improved hysteretic behavior and ameliorated performance with respect to the reference specimens. The effectiveness and the easy-to-apply character of the presented strengthening technique is also discussed.
Skin Color Retention in Red Potatoes during Long-Term Storage with Edible Coatings
Authors: Emragi Esam , Jayanty Sastry S.
Published: July 2021

In this study, we aimed to investigate the effect of edible coatings and cold storage conditions on the skin color of red potatoes (Ciklamen and Modoc) stored for six months at 4 ± 2 °C and 90 ± 5% relative humidity (RH). The four different formulations used were sodium alginate (F1), sodium alginate and potato starch (F2), zein and chitosan (F3), and chitosan, sodium alginate and potato starch (F4), in addition to the control treatment with distilled water. The treated samples were assessed periodically during six months of storage for changes in color, levels of reducing sugars, total phenolics and sensory qualities. The results indicated that the treatment with edible coatings significantly enhanced the chroma value of skin color, especially F1 and F2 formulations. However, these coatings instilled a limited effect on the level of reducing sugars. Moreover, F1 and F4 formulations exerted a significant effect (p < 0.05) on anthocyanin content examined after three months of storage. Alginate-based edible coatings significantly improved sensory evaluation, especially in terms of the color, gloss, and general acceptability of red skin potatoes.
The Impact of a Telehealth Intervention on Activity Profiles in Older Adults during the COVID-19 Pandemic: A Pilot Study
Authors: Johnson Nathaniel , Bradley Adam , Klawitter Lukus , Johnson Jane , Johnson Lance , Tomkinson Grant R. , Hackney Kyle J. , Stastny Sherri , Ehlers Diane K. , McGrath Ryan
Published: July 2021

Background: Physical inactivity during the COVID-19 pandemic is a public health concern for older adults. Telehealth presents a safe platform for conducting health-related interventions that may have additional benefits such as widespread reach. Our pilot study sought to examine how a telehealth intervention changed activity profiles in older adults during the COVID-19 pandemic. Methods: There were n = 13 adults aged 70.6 ± 4.5 years that participated in a 6 week telehealth intervention during the COVID-19 pandemic. The didactic intervention contents were shared online, and participants worked with trained interviewers over the telephone to discuss physical activity. At baseline and post-intervention, the Multimedia Activity Recall for Children and Adults examined activity profiles, while accelerometry estimated time spent sedentary and in physical activity. Results: Relative to the baseline measures, there was an 88 min/day (95% confidence interval (CI): 39, 137) increase in computer time and 36 min/day (CI: 10, 62) reduction in time spent in active transport at post-intervention. Moderate-to-vigorous physical activity participation also increased by an estimated 2 min/day (CI: −21, 26) and 12 min/week (CI: −154, 180), but this trend was not statistically significant. Conclusion: We recommend that support be provided to older adults transitioning to telehealth, especially as migration to telehealth progresses.
Radiology Community Attitude in Saudi Arabia about the Applications of Artificial Intelligence in Radiology
Authors: Alelyani Magbool , Alamri Sultan , Alqahtani Mohammed S. , Musa Alamin , Almater Hajar , Alqahtani Nada , Alshahrani Fay , Alelyani Salem
Published: July 2021

Artificial intelligence (AI) is a broad, umbrella term that encompasses the theory and development of computer systems able to perform tasks normally requiring human intelligence. The aim of this study is to assess the radiology community’s attitude in Saudi Arabia toward the applications of AI. Methods: Data for this study were collected using electronic questionnaires in 2019 and 2020. The study included a total of 714 participants. Data analysis was performed using SPSS Statistics (version 25). Results: The majority of the participants (61.2%) had read or heard about the role of AI in radiology. We also found that radiologists had statistically different responses and tended to read more about AI compared to all other specialists. In addition, 82% of the participants thought that AI must be included in the curriculum of medical and allied health colleges, and 86% of the participants agreed that AI would be essential in the future. Even though human–machine interaction was considered to be one of the most important skills in the future, 89% of the participants thought that it would never replace radiologists. Conclusion: Because AI plays a vital role in radiology, it is important to ensure that radiologists and radiographers have at least a minimum understanding of the technology. Our finding shows an acceptable level of knowledge regarding AI technology and that AI applications should be included in the curriculum of the medical and health sciences colleges.
Testing the Multi-Theory Model (MTM) to Predict the Use of New Technology for Social Connectedness in the COVID-19 Pandemic
Authors: Sharma Manoj , Batra Kavita , Flatt Jason
Published: July 2021

Loneliness or social isolation, recently described as a “behavioral epidemic,” remains a long-standing public health issue, which has worsened during the COVID-19 pandemic. The use of technology has been suggested to enhance social connectedness and to decrease the negative health outcomes associated with social isolation. However, till today, no theory-based studies were performed to examine the determinants of technology use. Therefore, the current study aims to test theory-based determinants in explaining the adoption of new technology in a nationally representative sample during the COVID-19 pandemic (n = 382). A psychometrically reliable and valid instrument based on the multi-theory model (MTM) of health behavior change was administered electronically using a cross-sectional study design. A total of 47.1% of the respondents reported high levels of social isolation, and 40.6% did not use any new technology. Among technology users (59.4%), the three initiation constructs participatory dialogue (b = 0.054, p < 0.05), behavioral confidence (b = 0.184, p < 0.001), and changes in the physical environment (b= 0.053, p < 0.05) were significant and accounted for 38.3% of the variance in the initiation of new technologies. Concerning sustenance in technology users, all three constructs emotional transformation (b = 0.115, p < 0.001), practice for change (b = 0.086, p < 0.001), and changes in the social environment (b = 0.061, p < 0.001) were significant and accounted for 42.6% of the variance in maintaining the use of new technology. MTM offers a powerful framework to design health promotion interventions encouraging the use of new technologies to foster greater social connectedness amid the COVID-19 pandemic and beyond it.
Acute High Level Noise Exposure Can Cause Physiological Dysfunction in Macaque Monkeys: Insight on the Medical Protection for Special Working Environmental Personnel
Authors: Zhi Weijia , Wang Haoyu , Zou Yong , Xu Xinping , Yu Ning , Zhu Yuyang , Ren Yanling , Ma Lizhen , Qiu Yefeng , Hu Xiangjun , Wang Lifeng
Published: July 2021

The high level noise caused by intense acoustic weapons and blasting is a common source of acute acoustic trauma faced by some special environmental personnel. Studies have shown that high level noise can cause auditory and non-auditory effects. However, there are few reports on the biological effects, especially the non-auditory effects of acute high level noise exposure in simulated special working environments, and the great differences between experimental animals and human beings make it difficult to extrapolate from research conclusions. In this study, macaque monkeys were used to detect the effects of acute high level noise exposure on hearing, cognition, and cardiovascular function. Auditory brainstem response, auditory P300, and electrocardiogram (ECG) of macaque monkeys were measured. Results showed that acute high level noise exposure caused permanent hearing threshold shifts; partial hearing loss which couldn’t recover to normal levels in the detection period; pathological changes in T wave and QRS complexes; and large fluctuations in cognitive ability after exposure, which finally recovered to normal. These alterations may be a combination of effects caused by stress-induced neuroendocrine dysfunction and mechanical damage of auditory organs. To elaborate the exact mechanism, further studies are still needed. Meanwhile, positive measures should be taken to reduce the incidence of acute high level noise injury.
Post-Harvest Non-Conventional and Traditional Methods to Control Cadophora luteo-olivacea: Skin Pitting Agent of Actinidia chinensis var. deliciosa (A. Chev.)
Authors: Di Francesco Alessandra , Di Foggia Michele , Vittoria Alessio , Baraldi Elena
Published: July 2021

Cadophora luteo-olivacea represents a critical problem for kiwifruit in the post-harvest phase, mainly for its little note epidemiology. The study presented some results about the possibility of preserving kiwifruit from skin pitting symptoms using alternative methods to fungicides. By in vitro assays, antagonist mechanisms of action against pathogen isolates were tested. Trichoderma harzianum (Th1) showed the highest inhibitory activity against C. luteo-olivacea isolates by volatile, non-volatile, and by dual culture assay, displaying an inhibition respectively by 90%, 70.6%, and 78.8%, and with respect to Aureobasidium pullulans (L1 and L8) by 23.3% and 25.8%, 50% and 34.7%, and 22.5% and 23.6%, respectively. Further, the sensitivity on CFU and mycelial growth of C. luteo-olivacea isolates to fludioxonil, and CaCl2 was tested, displaying interesting EC50 values (0.36 and 0.92 g L−1, 22.5 g L−1, respectively). The effect of Brassica nigra defatted meal was tested as biofumigation assays and through FT-IR (Fourier-Transform Infrared) spectroscopy. The above-mentioned treatments were applied in vivo to evaluate their efficacy on kiwifruits. Our data demonstrated that alternative solutions could be considered to control postharvest pathogens such as C. luteo-olivacea.
Development of Micropropagation in Bigleaf Maple (Acer macrophyllum)
Authors: Zhou Chen , Mattsson Jim
Published: July 2021

Natural populations of bigleaf maple (Acer macrophyllum Pursh) trees contain, at low frequency, individuals with stems that have attractive and valuable wavy grain in the wood. To maintain the genotype of these individuals, vegetative propagation is desired. To enable propagation from the limited amount of plant tissue that is often available, an in vitro micropropagation procedure was developed. A mix of wild trees was used as source material to generate a procedure that is genotype unspecific. Among tested basal media, DKW medium resulted in the highest frequency of growing shoots. For multiplication of shoots, removal of the apex of shoot explants was instrumental, presumably because this treatment broke a strong apical dominance in this species. Of tested hormone and hormone combinations, 0.1 μM thidiazuron produced the best results with an average of 3.2 axillary shoots per explant with an average of 3.7 nodes per axillary shoot after 1 month. Although rooting did not require hormone treatment, a 68% frequency of rooting was obtained on ½ MS supplemented with 1 μM IBA, 27% higher than hormone-free media. Taken together, we have developed a procedure for propagation of bigleaf maple from a limited amount of tissues that can be used to multiply various genotypes of interest.
Effects of Soil Aeration and Fertilization Practices on Alleviating Iron Deficiency Chlorosis in “Huangguan” Pears Grafted onto Quince A in Calcareous Soils
Authors: Zhao Yanyan , Li Haigang , Sun Mingde , Liang Zhenxu , Yu Futong , Li Fei , Liu Songzhong
Published: July 2021

In North China, the high-quality pear cultivar “Huangguan” (Pyrus bretschneideri Rehd. cv), which is grafted onto dwarf quince A (Cydonia oblonga Mill. cv) rootstock and grown in calcareous soil, experiences severe iron (Fe) deficiency; this deficiency greatly constrains tree growth as well as fruit yield and quality. Therefore, we evaluated the effects of six practices for alleviating chlorosis caused by Fe deficiency in “Huangguan” grafted onto quince A (HG-QA). The practices included ridging with landscape fabric mulching as a control, flattening with landscape fabric mulching (FM), ridging without landscape fabric mulching (R), flattening without landscape fabric mulching (F), Fe fertilizer application in soil (SFe), foliar Fe application (FFe), and manure application (M). The results showed that the leaf Fe concentration increased by 356% under FFe, compared to that under the control, but the practice failed to alleviate Fe deficiency chlorosis. In contrast, an increase in leaf Fe concentration and chlorosis alleviation were observed under F. F alleviated chlorosis mainly by increasing the root ferric-chelate reductase activity. These results indicate that Fe uptake and utilization in leaves are independent biochemical processes and soil aeration improvement have positive effect on increasing Fe uptake. M improved both the soil active Fe concentration and leaf Fe utilization. Thus, manure application should be the first choice for alleviating Fe deficiency chlorosis in HG-QA grown in calcareous soils. Combining manure application with other practices that increase Fe uptake would likely be an effective way to address the problem of Fe deficiency chlorosis.
Screening of USDA Onion Germplasm for Fusarium Basal Rot Resistance
Authors: Mandal Subhankar , Cramer Christopher S.
Published: July 2021

Fusarium basal rot (FBR) caused by Fusarium oxysporum f. sp. cepae (FOC) is a major threat to onion (Allium cepa L.) production and marketing worldwide. Finding new sources of FBR-resistance to develop synthetic cultivars is a priority for onion breeders. As there are no FBR-resistant short-day onion cultivars, 85 U.S. National Plant Germplasm System plant introduction onion accessions that originated from 23 different countries were screened for their FBR susceptibility. To compare FBR susceptibility of these accessions at their seedling and mature bulb stages, a susceptible check cultivar, NuMex Crimson, a partially resistant check cultivar, Serrana and its selected population, Serrana-sel, were included in the study. The seedling screening was performed after inoculating silica-sand media with a virulent FOC isolate ‘CSC-515’ at 1.0 × 104 macroconidia g−1 of sand. Each entry was evaluated twice in growth chambers, and percent survival was adjusted to the number of seedlings that germinated in the uninoculated trays. Mature bulbs produced in the field were screened by inoculating transversely cut basal plates with potato dextrose agar plugs containing spores of the same isolate at 3.0 × 104 macroconidia mL−1. FBR severity and incidence were then calculated after 20 days of incubation. Significant variation was found among the accessions for FBR-susceptibility (p < 0.001) at both the seedling and the mature bulb stages. Two sets of 18 accessions were identified either for their higher seedling survival or higher mature bulb FBR-resistance compared to the checks. Among them, PI 256326 (‘Baia Periforme’, the originator cultivar of ‘Serrana’) had a higher seedling survival than both the checks, and a lower mature bulb severity than the susceptible check. Another accession, PI 656956 (‘S015’), exhibited higher seedling survival than the susceptible check and a low FBR severity (4.3 on a 1 to 9 scale) and incidence (41.7%). These two accessions, which were known previously for their high intra-population heterogeneity and root or bulb resistance for FBR, respectively, show promise for incorporating FBR-resistance into short-day onion cultivars. The cultivar rankings could vary in future studies with a range of FOC isolates due to a high cultivar × isolate interaction as observed in past studies.
Untargeted GC-TOFMS Analysis Reveals Metabolomic Changes in Salvia miltiorrhiza Bunge Leaf and Root in Response to Long-Term Drought Stress
Authors: Zhang Jin , Su Yuekai , Li Jingyu , Ren Zhenli , Tian Guoqing , Wang Jianhua
Published: July 2021

Salvia miltiorrhiza Bunge (Danshen) is an important traditional Chinese medicine herb. This study aimed to investigate the drought-responsive metabolic profiling in S. miltiorrhiza using gas chromatography time-of-flight mass spectrometry (GC-TOFMS) analysis. Fifty day-old S. miltiorrhiza seedlings were treated with two (moderate drought, MD) and four weeks (high drought, HD) of withholding water. The S. miltiorrhiza leaf and root samples were prepared for the GC-TOFMS analysis. Differential metabolites with substantial changes in content in S. miltiorrhiza leaf and root were identified using multivariate and univariate statistics. A total of 178 and 157 annotated metabolites were detected in S. miltiorrhiza leaf and root, respectively. Multivariate analysis showed that significantly discriminant metabolites in S. miltiorrhiza leaf by drought were associated with “galactose metabolism” and “citrate cycle”. In addition, the significantly discriminant metabolites in S. miltiorrhiza root were associated with “starch and sucrose metabolism”. Univariate statistics showed that the content of succinic acid, d-glucose, and oxoglutaric acid in S. miltiorrhiza leaf was increased by drought (fold change, FC > 1.5). Allose, d-xylose, melibiose, mannose, sorbitol, quinic acid, sinigrin, and taurine in S. miltiorrhiza root were decreased by drought (FC < 0.67). There were different metabolic profiles between S. miltiorrhiza leaf and root. However, the influence of drought stress on the pharmacological value and accumulation of bioactive constituents in S. miltiorrhiza should be further investigated.
Correlation between Official and Common Field-Based Fitness Tests in Elite Soccer Referees
Authors: Romano Veronica , Tuzi Manuel , Di Gregorio Ada , Sacco Anna Maria , Belviso Immacolata , Sirico Felice , Palermi Stefano , Nurzynska Daria , Di Meglio Franca , Castaldo Clotilde , Pizzi Angelo , Montagnani Stefania
Published: July 2021

Official tests are used to assess the fitness status of soccer referees, and their results correlate with match performance. However, FIFA-approved tests expose the referees to high physical demands and are difficult to implement during the sportive year. The aim of our study was to evaluate the correlation between the 6 × 40-m sprint and Yo-Yo Intermittent Recovery Level 1 (IR1) official tests and other field-based tests that require no or little equipment, are not time-consuming, and impose low physical demands. All tests were performed by male referees from the Regional Section of the Italian Referee Association (n = 30). We observed a strong correlation between 6 × 40-m sprint and Illinois agility tests (r = 0.63, p = 0.001) and a moderate correlation between Yo-Yo IR1 and hand-grip strength in the dominant (r = 0.45, p = 0.014) and non-dominant hand (r = 0.41, p = 0.031). Interestingly, only a moderate correlation (r = −0.42, p = 0.025) was observed between the FIFA official tests, 6 × 40-m sprint and Yo-Yo IR1. These results suggest that Illinois agility and hand-grip tests could represent simple and low-physical-impact tools for repeated assessment and monitoring of referee fitness throughout the sportive season.
Numerical Study on Interaction between Submarine Landslides and a Monopile Using CFD Techniques
Authors: Li Ru-Yu , Chen Jin-Jian , Liao Chen-Cong
Published: July 2021

Offshore installations with pile foundations in shallow water are vulnerable to submarine landslides, which cause serious damage to engineering facilities, loss of life, and loss of money. Due to a shortage of real observation data and the difficulty of reproduction, we lack insight into the interaction behavior between submarine landslides and monopiles. This study capitalized on ANSYS Fluent 20.0 to develop a three-dimensional biphasic (water and slurry) numerical model. This CFD model was used to analyze the interaction between a monopile and submarine landslides at different flow heights. The velocities of submarine landslides were from low to high values. Two modes of interactional forces acting on the monopile are proposed, which are (i) interaction force with peak value and (ii) interaction force without peak value. The influence of flow height and velocity on interaction forces was investigated. Results show that the effect of the flow heights on the interaction force is significant at low velocity stage, while the peak force representing a hazard level of the pile was non-negligible under high flow velocity and low flow height conditions, which should be considered in a future study. The related mechanisms are revealed with a hybrid model considering different components of the force.
Reporting Strategy and Gender Perspective in Chinese Media Coverage of COVID-19 News
Authors: Yang Yi , Liu Xunqian
Published: July 2021

This article examines the reporting strategy and gender perspective in Chinese media coverage of COVID-19 news. The article employs a mixed-method approach to analyze news reports, using quantitative statistics and qualitative semantic materials that complement each other. The study found that the media construct a stereotypical image of female healthcare workers absent from public participation. Media reports on the actual number of female healthcare workers involved in treating COVID-19 patients are lower than those about men. Reports focusing exclusively on female staff tend to focus on their private affairs, that is, on their non-professional identities and characteristics, and show an excessive gaze on the female body. To understand this phenomenon prevailing in Chinese media, it is necessary to highlight the predicament of Chinese women in society as well as acknowledge the work of contemporary Chinese feminism in raising awareness on Chinese women’s experiences.
Impact of Emotional Perceived Value on the Uncertain Evolution of the Housing Bubble
Authors: Tang Yang , Hong Kairong , Zou Yucheng , Zhang Yanwei
Published: July 2021

In China, the housing bubble is not only an economic issue but also an important social and political issue. According to game theory, the housing bubble is an equilibrium result of the interaction between policy environment and participants’ behavior. In this process, due to the interaction between speculation, regulation, and emotions, the development and evolution of the housing bubble are faced with uncertainty. Different from traditional econometric analysis, this article adopts the evolutionary game analysis method in order to establish a multi-stage evolutionary game analysis framework for the housing bubble. Firstly, by analyzing the emotional perceived value of related subjects under optimism, pessimism, and uncertainty, this article explores the mechanism of emotional perceived value on the housing bubble under the condition of inconsistent policy objectives. Secondly, it introduces emotional perceived value into the evolutionary game analysis framework of housing bubbles and analyzes the strategic combination and game equilibrium between investors and local governments under different emotions. Finally, taking Hainan province as an example, it conducts a MATLAB numerical simulation on the uncertain evolution of the housing bubble and proposes a staged strategy combination to deal with the housing bubble. The results show that: (1) emotional perceived value is affected by policy environment; (2) changes in the strength of policy effects make emotional perceived value change, which has different incentive effects on investors’ speculation and local governments’ regulation; (3) there are differences in emotional perceived value in different stages, which improves the uncertainty of the game equilibrium result between investors and local governments; and (4) considering the evolutionary characteristics of the housing bubble in different stages, its countermeasures should not only prevent insufficient regulation but also avoid excessive regulation. The above conclusions can provide theoretical and practical references for predicting the behavior of real estate investors, identifying the evolution mechanisms and rules of real estate bubbles and formulating relevant regulatory policies.
Time-Dependent Reliability Analysis of Plate-Stiffened Prismatic Pressure Vessel with Corrosion
Authors: Choi Younseok , Ahn Junkeon , Chang Daejun
Published: July 2021

In this study, the structural reliability of plate-stiffened prismatic pressure vessels was analyzed over time. A reliability analysis was performed using a time-dependent structural reliability method based on the response surface method (RSM). The plate-stiffened prismatic pressure vessel had a rectangular cross-section with repeated internal load-bearing structures. For the structural analysis, this repeated structure was modeled as a strip, and a structural reliability analysis was performed to identify changes in the reliability index when general corrosion and pitting corrosion occurred in the outer shell. Pitting corrosion was assumed to be randomly distributed on the outer shell, and the reliability index according to the degree of pit (DOP) and time was analyzed. Analysis results confirmed that the change in the reliability index was larger when pitting corrosion was applied compared with when only general corrosion was applied. Additionally, it was confirmed that above a certain DOP, the reliability index was affected.
Gamma Generalization Operators Involving Analytic Functions
Authors: Cai Qing-Bo , Çekim Bayram , İçöz Gürhan
Published: July 2021

In the present paper, we give an operator with the help of a generalization of Boas–Buck type polynomials by means of Gamma function. We have approximation properties and moments. The rate of convergence is given by the Ditzian–Totik first order modulus of smoothness and the K-functional. Furthermore, we obtain the point-wise estimations for this operator.
Model of Price Optimization as a Part of Hotel Revenue Management—Stochastic Approach
Authors: Petricek Martin , Chalupa Stepan , Melas David
Published: July 2021

The paper is focusing on the problem of price optimization in the area of accommodation services. The main aim is to propose a novel simulation-based methodology of price optimization based on the customer’s price acceptance. The authors create a model based on the known approaches but extended by the stochastic approach and optimization based on the coefficient of price elasticity. The whole model is created, the price is set and optimized in two steps. The first step makes segmentation and optimization (with the price elasticity approach). The second step then sets the price of the reservation—the final price for a customer. This reservation price is mainly determined by knowledge of the length of stay, occupancy and booking lead time. All those parameters are described in the text from the economic point of view and make the base for the whole and complex revenue management model.
Case-Based Reasoning for Hidden Property Analysis of Judgment Debtors
Authors: Zhang Huirong , Zhang Zhenyu , Zhou Lixin , Wu Shuangsheng
Published: July 2021

Many judgment debtors try to evade, confront, and delay law enforcement using concealing and transferring their property to resist law enforcement in China. The act of hiding property seriously affects people’s legitimate rights and interests and China’s legal authority. Therefore, it is essential to find an effective method of analyzing whether a judgment debtor hides property. Aiming at the hidden property analysis problem, we propose a case-based reasoning method for the judgment debtor’s hidden property analysis. In the hidden property analysis process, we present the attributes of the enforcement case by crisp symbols, crisp numbers, interval numbers, and fuzzy linguistic variables and develop a hybrid similarity measure between the historical enforcement case and the target enforcement case. The results show that the recommendations obtained with the information and knowledge of similar historical cases are consistent with judicial practice, which can reduce the work pressure of law enforcement officers and improve the efficiency of handling enforcement cases.
Anisotropic Network Patterns in Kinetic and Diffusive Chemotaxis Models
Authors: Thiessen Ryan , Hillen Thomas
Published: July 2021

For this paper, we are interested in network formation of endothelial cells. Randomly distributed endothelial cells converge together to create a vascular system. To develop a mathematical model, we make assumptions on individual cell movement, leading to a velocity jump model with chemotaxis. We use scaling arguments to derive an anisotropic chemotaxis model on the population level. For this macroscopic model, we develop a new numerical solver and investigate network-type pattern formation. Our model is able to reproduce experiments on network formation by Serini et al. Moreover, to our surprise, we found new spatial criss-cross patterns due to competing cues, one direction given by tissue anisotropy versus a different direction due to chemotaxis. A full analysis of these new patterns is left for future work.
Antioxidant Serine-(NSAID) Hybrids with Anti-Inflammatory and Hypolipidemic Potency
Authors: Theodosis-Nobelos Panagiotis , Papagiouvannis Georgios , Tziona Paraskevi , Kourounakis Panos N. , Rekka Eleni A.
Published: July 2021

A series of L-serine amides of antioxidant acids, such as Trolox, (E)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)acrylic acid (phenolic derivative of cinnamic acid) and 3,5-di-tert-butyl-4-hydroxybenzoic acid (structurally similar to butylated hydroxytoluene), was synthesized. The hydroxy group of serine was esterified with two classical NSAIDs, ibuprofen and ketoprofen. The Trolox derivatives with ibuprofen (7) and ketoprofen (10) were the most potent inhibitors of lipid peroxidation (IC50 3.4 μΜ and 2.8 μΜ), several times more potent than the reference Trolox (IC50 25 μΜ). Most of the compounds decreased carrageenan-induced rat paw edema (37–67% at 150 μmol/kg). They were moderate inhibitors of soybean lipoxygenase, with the exception of ibuprofen derivative 8 (IC50 13 μΜ). The most active anti-inflammatory compounds exhibited a significant decrease in lipidemic indices in the plasma of Triton-induced hyperlipidemic rats, e.g., the most active compound 9 decreased triglycerides, total cholesterol and low-density lipoprotein cholesterol by 52%, 61% and 70%, respectively, at 150 μmol/kg (i.p.), similar to that of simvastatin, a well-known hypocholesterolemic drug. Since the designed compounds seem to exhibit multiple pharmacological actions, they may be of use for the development of agents against inflammatory and degenerative conditions.
A Global Survey on Opioid Stewardship Practices in Hospitals: A Cross-Sectional Pilot Study
Authors: Al-Samawy Sarah , Varughese Nisha , Vaillancourt Regis , Wang Xiao Yu (William) , Penm Jonathan
Published: July 2021

Objective: The objectives of this study are to describe opioid stewardship practices in hospitals being implemented globally, in addition to investigating the attitudes and perceptions of health professionals regarding opioid stewardship in the hospital setting. Methods: A survey was developed by the research team to ask about participants’ attitudes and perceptions regarding opioid stewardship practices. The survey was piloted for performance by five independent third-party healthcare professionals prior to being made available online, being hosted using Research Electronic Data Capture software, with invitations distributed by the International Pharmaceutical Federation (FIP). Descriptive analyses were used to describe the features of the study, and responses obtained from the survey were further categorised into subgroups separating answers relating to attitudes and perceptions, and policies and regulations. Results: Overall, there were 50 respondents from 18 countries, representing an 8% response rate from the FIP hospital pharmacy section mailing list. In total, 33/50 (66%) participants agreed opioids are overused nationally, with 22/49 (45%) agreeing they are overused at their workplace. Furthermore, 32/50 (64%) agreed the opioid crisis is a significant problem nationally, and 44/50 (88%) agreed opioid stewardship would reduce problems associated with the opioid crisis. Policies to educate providers about safe opioid prescribing were uncommon, not exhibited in 26/46 (57%) of hospitals, with all EMR and SE Asia hospitals not displaying this policy. Policy for investigation of narcotic discrepancies was present in 34/46 (74%) of hospitals, and there was a policy for reporting discrepancies at 33/46 (72%) hospitals. Conclusion: In conclusion, healthcare professionals in the American region are more likely to perceive the opioid crisis as a problem, as opposed to those from the European region. Regardless of the presence or absence of a crisis, the implementation of further opioid education and stewardship practices are necessary globally and will contribute to safer prescribing and utilisation practices in hospitals.
Tracking Control of X-Z Inverted Pendulum with Block Backstepping
Authors: Xin Zhuang-Zhuang , Wang Jia-Jun
Published: July 2021

As the extension of traditional linear (or X) inverted pendulum (IP), X-Z IP is a multiple-input multiple-output (MIMO), underactuated, open-loop unstable, and nonlinear system. In the tracking control of the X-Z IP, the equilibrium point changes with the pivot position of the pendulum. This makes linear control theories have difficulties in realization of the tracking control for the pendulum. The underactuated feature of the pendulum makes the feedback linearization unsuitable to simplify the control design. With the present model of the X-Z IP, there is no way to realize the backstepping design. This paper gives a novel state transformation method for the X-Z IP. Through the state transformation, the block backstepping can be easily deployed in the controller design of the X-Z IP. The proposed controller can achieve the tracking control in the vertical plane. Simulation results certify the rightness and effectiveness of the proposed tracking controller.
Transport Parameter Correlations for Digitally Created PEFC Gas Diffusion Layers by Using OpenPNM
Authors: Encalada-Dávila Ángel , Espinoza-Andaluz Mayken , Barzola-Monteses Julio , Li Shian , Andersson Martin
Published: July 2021

A polymer electrolyte fuel cell (PEFC) is an electrochemical device that converts chemical energy into electrical energy and heat. The energy conversion is simple; however, the multiphysics phenomena involved in the energy conversion process must be analyzed in detail. The gas diffusion layer (GDL) provides a diffusion media for reactant gases and gives mechanical support to the fuel cell. It is a complex medium whose properties impact the fuel cell’s efficiency. Therefore, an in-depth analysis is required to improve its mechanical and physical properties. In the current study, several transport phenomena through three-dimensional digitally created GDLs have been analyzed. Once the porous microstructure is generated and the transport phenomena are mimicked, transport parameters related to the fluid flow and mass diffusion are computed. The GDLs are approximated to the carbon paper represented as a grouped package of carbon fibers. Several correlations, based on the fiber diameter, to predict their transport properties are proposed. The digitally created GDLs and the transport phenomena have been modeled using the open-source library named Open Pore Network Modeling (OpenPNM). The proposed correlations show a good fit with the obtained data with an R-square of approximately 0.98.
Effect of a Baffle on Bubble Distribution in a Bubbling Fluidized Bed
Authors: Xing Xuelian , Zhang Chao , Jiang Bin , Sun Yongli , Zhang Luhong , Briens Cedric
Published: July 2021

In this study, the multi-phase Eulerian–Eulerian two-fluid method (TFM) coupled with the kinetic theory of granular flow (KTGF) was used to investigate the hydrodynamics of particle flows (Geldart Group B) in a lab-scale bubbling fluidized bed. The goal was to improve the bubble flow behavior inside the fluidized bed to improve the distribution of an injected liquid, by increasing the flow of bubbles entering the spray jet cavity and, thus, reduce the formation of wet agglomerates. The effects of a baffle on both the injection level and the whole fluidized bed were studied. Different baffle geometries were also investigated. Adding a fluxtube to a baffle can improve the bubble flows and a long fluxtube works best at redirecting gas bubbles. Baffles tend to smooth out variations in the gas distribution caused by the non-uniform inlet gas distribution. A gas pocket appears under all the baffles.
Multi Set-Point Explicit Model Predictive Control for Nonlinear Process Systems
Authors: Charitopoulos Vassilis M. , Papageorgiou Lazaros G. , Dua Vivek
Published: July 2021

In this article, we introduce a novel framework for the design of multi set-point nonlinear explicit controllers for process systems engineering problems where the set-points are treated as uncertain parameters simultaneously with the initial state of the dynamical system at each sampling instance. To this end, an algorithm for a special class of multi-parametric nonlinear programming problems with uncertain parameters on the right-hand side of the constraints and the cost coefficients of the objective function is presented. The algorithm is based on computed algebra methods for symbolic manipulation that enable an analytical solution of the optimality conditions of the underlying multi-parametric nonlinear program. A notable property of the presented algorithm is the computation of exact, in general nonconvex, critical regions that results in potentially great computational savings through a reduction in the number of convex approximate critical regions.
On the Application of ARIMA and LSTM to Predict Order Demand Based on Short Lead Time and On-Time Delivery Requirements
Authors: Wang Chien-Chih , Chien Chun-Hua , Trappey Amy J. C.
Published: July 2021

Suppliers are adjusting from the order-to-order manufacturing production mode toward demand forecasting. In the meantime, customers have increased demand uncertainty due to their own considerations, such as end-product demand frustration, which leads to suppliers’ inaccurate demand forecasting and inventory wastes. Our research applies ARIMA and LSTM techniques to establish rolling forecast models, which greatly improve accuracy and efficiency of demand and inventory forecasting. The forecast models, developed through historical data, are evaluated and verified by the root mean squares and average absolute error percentages in the actual case application, i.e., the orders of IC trays for semiconductor production plants. The proposed ARIMA and LSTM are superior to the manufacturer’s empirical model prediction results, with LSTM exhibiting enhanced performance in terms of short-term forecasting. The inventory continued to decline significantly after two months of model implementation and application.