bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS POROSITAS PENGECORAN LOGAM CETAKAN PLASTER DENGAN VARIASI KOMPOSISI BAHAN PLASTER DAN AIR DENGAN MENGGUNAKAN SCANNING ELECTRON MICROSCOPE (SEM)
Authors: Afianto Firly , Romlie Maftuchin , Yoto Yoto
Published: December 2023

Cetakan plaster adalah salah satu tipe cetakan dalam pengecoran logam, ada beberapa faktor lain yang dapat menghasilkan coran dengan kualitas yang bagus, seperti komposisi cetakan bahan pengikatnya atau bahan dasarnya dan pengeringan cetakan dengan tepat. Penelitian ini bertujuan untuk mengetahui komposisi yang sesuai dengan cetakan plaster dengan pengikat air, sebagai analisis cacat porositas pada hasil pengecoran cetakan plaster menggunakan Scanning Electron Microscope dan analisis nilai kekerasan pada pengecoran cetakan plaster. Penelitian ini menggunakan metode penelitian kuantitatif dengan metode one-shot case study. Adapun hasil dari penelitian ini menunjukan pada hasil uji visual didapatkan dari cetakan plaster 43%, 46% dan 50% semua memiliki cacat penyinteran dan rongga udara. Berdasarkan hasil pengamatan struktur mikro coran cetakan plaster 50% cacat porositas banyak terjadi dengan penyebaran strukur butir alumunium tidak merata dan butir silikon yang kecil. Berdasarkan nilai kekerasan microvickers tertinggi terdapat pada coran 50% dengan nilai kekerasan 97,1 HV lebih tinggi dari coran 43% dengan nilai kekerasan 96,2 HV. Dapat disimpulkan bahwa seiring bertambahnya air dan berkurangnya plaster, nilai kekerasannya akan berkurang.
Effects of Mitral Valve Surgery on Ventricular Arrhythmia in Mitral Valve Prolapse Patients: Five-Year Eollow-up
Authors: Malev E. G. , Omelchenko M. Yu. , Reeva S. V. , Mitrofanova L. B. , Parfenova N. N. , Timofeev E. V.
Published: December 2023

Aim      To evaluate the effect of mitral valve (MV) repair and replacement on the incidence of ventricular arrhythmias (VA) and to identify risk factors for the persistence of VA in patients with MV prolapse and severe mitral regurgitation (MR) during a mid-term follow-up.

Material and methods  A single-site observational, prospective study successively enrolled 30 patients (mean age, 55.2±9.9 years, 60% men) who underwent MV repair or replacement for severe MR due to MV prolapse or chordal avulsion. Transthoracic echocardiography and Holter monitoring were performed in all patients before and annually after surgery. A pathomorphological study of MV fragments excised during surgery was performed.

Results During the five-year follow-up period (144 person-years), one case of sudden cardiac death outside a health care facility was recorded. MR severity progressed in three patients after MV repair. The total number of all VAs decreased during the follow-up period, with a significant decrease in the number of paroxysms of unstable ventricular tachycardia during the first two years after surgery. The presence of VA in the postoperative period was correlated with the severity of postoperative left ventricular (LV) remodeling: end-diastolic volume (EDV) (rs=0.69; p=0.005), LV ejection fraction (EF) (rs = -0.55; p=0.004) and severity of MV myxomatous alterations according to histological study data (rτ=0.58; p=0.045). The beta-blocker treatment did not influence the VA frequency and severity (rs= -0.18; p=0.69). According to a univariate regression analysis only EDV (p = 0.001), LVEF <50% (p = 0.003), and myxomatous MV degeneration (p = 0.02) were risk factors for persistent ventricular tachycardia in the postoperative period.

Conclusion      Surgical intervention on MV in patients with MV prolapse and severe MR decreased the number of cases of malignant VAs and was correlated with the postoperative changes in LV volume and function, as well as the severity of MV myxomatous alterations.
Prevalence and Prognostic Value of Non-Alcoholic Fatty Liver Disease in Patients Hospitalized With Decompensated Chronic Heart Failure
Authors: Misan I. A. , Arisheva O. S. , Garmash I. V. , Cabello F. R. , Kobalava Zh. D.
Published: December 2023

Aim    To study the incidence and effect of non-alcoholic fatty liver disease (NAFLD) on clinical outcomes in patients with decompensated chronic heart failure (DCHF).Material and methods    The study included 338 patients with NYHA functional class III-IV DCHF (51.2% men, mean age 72.8±11.7 years), arterial hypertension (AH) in 90%, myocardial infarction in 37%, atrial fibrillation in 64%, chronic kidney disease (CKD) in 42%, type 2 diabetes mellitus (T2DM) in 35%, left ventricular ejection fraction (LVEF) <40% in 27%. NAFLD was diagnosed based on the 2021 Clinical Guidelines of the Russian Scientific Medical Society of Therapists and the Scientific Society of Gastroenterologists of Russia. The stage of liver steatosis was determined using transient elastometry with assessment of the controlled attenuation parameter (CAP) of ultrasound (S, dB/m) using a FibroScan device. Threshold CAP values <294 dB/m corresponded to the degree of steatosis: S0; S1, 295-309 dB/m; S2, 310-330 dB/m; S3, ≥331 dB/m.Results    NAFLD was diagnosed in 28.9% of patients. The patients were divided into two groups: group 1 included patients with CHF and NAFLD (n=98 (28.9%), 50.0% men) and group 2 included patients with CHF without NAFLD (n=240 (71.0 %), 51.6% men). A multivariate regression analysis showed that independent predictors of NAFLD were systolic blood pressure ≥130 mm Hg (odds ratio (OR), 3.700; p <0.001), history of T2DM (OR, 2.807; p <0.005), and waist circumference >111 cm (OR, 2.530; p <0.012). Patients with CAP ≥331 dB/m (S3) had a worse prognosis during the 2-year follow-up for the composite adverse outcome (all-cause mortality + readmission) (Kaplan-Meier curves - Log-Rank p=0.035).Conclusions    NAFLD was detected in almost one-third of patients hospitalized for DCHF. AH, T2DM, and abdominal obesity were associated with a high risk of NAFLD. However, only severe steatosis (S3) was an independent predictor of adverse clinical outcomes during a 2-year period after adjustment for known risk factors.
Right Ventricular Function in Surgical Treatment of Left Heart
Authors: Slivneva I. V. , Farulova I. Yu. , Skopin I. I. , Pirushkina Yu. D. , Murysova D. V. , Marapov D. I. , Golukhova E. Z.
Published: December 2023

Aim    The aim of this study was to evaluate right ventricular (RV) function during left chamber surgery.Material and methods    This was a single-site prospective cohort study. The study included 197 patients with valvular pathology of heart left chambers. Mean age of patients was 58 [47; 65] years. Precordial echocardiography was performed preoperatively and within one week after surgery.Results    Decreased parameters of the right ventricular (RV) longitudinal function and global contractile function were observed postoperatively in the majority of patients. More noticeable decreases were observed in parameters of the longitudinal function (p<0.001). Analysis of the changes in RV contractility depending on the underlying pathology revealed the greatest changes in the contractile function in the mitral insufficiency group. In the mitral stenosis group, the greatest difference was observed in the tricuspid annular systolic excursion (TAPSE) (p=0.027). In the groups with aortic defects, all parameters of RV contractile function, except for the fractional area change (FAC), showed statistically significant decreases after correction of the underlying defect (p<0.05).Conclusions    Surgical intervention for left heart valvulopathy can result in a decrease in RV function unrelated with systolic deficit of the left ventricle. Modern technologies allow multi-vector assessment of the RV contractile function. To assess the RV function, it is advisable to use a combination of parameters that reflect both global and longitudinal function.
The Role of Arterial Elasticity in Determining the Degree of Chronic Heart Failure in Myocardial Infarction
Authors: Lakomkin V. L. , Abramov A. A. , Prosvirnin A. V. , Kapelko V. I.
Published: December 2023

Aim      To study the left ventricular (LV) contractile and pumping function during the recovery phase following ligation of the anterior descending coronary artery (CA).

Material and methods  Cardiodynamic parameters were studied in Wistar rats 2-4 weeks after experimental myocardial infarction (MI). MI was induced by ligation of the anterior descending CA under zoletil anesthesia. LV catheterization was performed with a standard FTH-1912B-8018 PV catheter inserted into the LV through the right carotid artery.

Results After the induction of MI, the mortality rate of animals was 50%. Survived animals developed significant LV dilatation and a decrease in ejection fraction (EF) by an average of 31%. However, major indexes of the pumping function, including minute volume, heart work, and maximum ejection velocity, were within a normal range whereas the maximum filling velocity was almost doubled. Approximately 50% of hearts with dilated LV had normal EF, delayed relaxation, and increased LV diastolic pressure, which qualified this group as a diastolic dysfunction group. The systolic dysfunction group with EF less than 50% of normal had similar values of myocardial contractility and relaxation but differed from the diastolic dysfunction group in more than 50% reduced maximum LV ejection velocity and 1.7 times increased elasticity of the arterial wall. A close inverse correlation was found between these values (r= -0.91).

Conclusion      The study results showed that, with a similar myocardial contractile function, the cardiac pumping function is determined by the elasticity of the aortic wall. Therefore, restriction of reactive fibrosis during MI is an important task of modern cardiology.
Stress, Anxiety and Depressive Symptoms are Predictors of Worse Outcomes in Outpatients With Arterial Hypertension and Coronary Heart Disease: Results of 1.5 Years Follow-up From the COMETA Multicenter Study
Authors: Pogosova N. V. , Ausheva A. K. , Saner H. , Boytsov S. A.
Published: December 2023

Aim      To study associations between the risk of severe adverse cardiovascular outcomes (SACVO) and all-cause death with psychosocial risk factors (PS RFs), such as stress, anxiety and depressive symptoms, low level of education, low income, social isolation, and type D personality, in patients with arterial hypertension (AH) and ischemic heart disease (IHD) managed in primary health care institutions in a multi-year prospective study.

Material and methods  PS RFs were assessed in patients with AH or IHD, who participated in a multi-year prospective COMETA study, using the Hospital Anxiety and Depression Scale (HADS), DS-14 questionnaire, and a visual analogue scale (VAS) for assessment of stress level. Associations of PS FRs with SACVO and all-cause death after a 1.5-year follow-up were analyzed using multivariate Cox regression models.

Results At 1.5 years after patients were included in the study, it was possible to obtain data for 2,538 patients (age at baseline, 66.6 ± 7.8 years, 28.1% men), 106 of whom died during that period. The incidence of SACVO was 40.0 per 1000 person-years. According to the results of multivariate regression analysis, a very high level of anxiety symptoms (HADS-A≥14) was significantly associated with SACVO (odds ratio (OR), 1.81; 95% confidence interval (CI), 1.04-3.15; p=0. 02). The composite endpoint that included all-cause death and/or SACVO was significantly associated with a high (VAS score ≥8) stress level (OR, 1.53; 95% CI, 1.00-2.33; p=0.04) and a very high (HADS-D≥14) level of depressive symptoms (OR, 2.11; 95% CI, 1.22-3.62; p=0.02). A low level of education adjusted for gender and age increased the likelihood of SACVO by 1.7 (95% CI, 1.19-2.43) times. No significant associations were found between the analyzed outcomes and type D personality or with social isolation.

Conclusion      In patients with AH or IHD, the presence of high-grade stress and severe depressive symptoms increased the likelihoods of all-cause death and SACVO while a low level of education and severe anxiety symptoms were associated with SACVO. The study results showed that PS RFs for cardiovascular diseases keep the PS RF prognostic significance in the conditions of modern treatment of AH and IHD. Due to the negative impact on the prognosis, PS RFs should be taken into account when taking measures for secondary prevention of AH and IHD
The Prognostic Significance of Atrial Fibrillation and Left Atrium Size in Patients with Aortic Stenosis
Authors: Pińska Małgorzata , Sorysz Danuta , Frączek-Jucha Magdalena , Kruszec Paweł , Róg Beata , Myć Jacek , Krawczyk-Ożóg Agata , Sobień Bartosz , Stopyra-Pach Katarzyna , Sarnecka Agnieszka , Stąpór Maciej , Olszanecka Agnieszka , Golińska-Grzybała Karolina , Nessler Jadwiga , Gackowski Andrzej
Published: December 2023

Aim    Aortic stenosis increases left atrial (LA) pressure and may lead to its remodeling. This can cause supraventricular arrhythmia. The aim of this study was to determine if the size of the LA and the presence of atrial fibrillation are related to the prognosis of patients with aortic stenosis.Material and methods    Clinical evaluation and standard transthoracic echocardiographic studies were performed in 397 patients with moderate to severe aortic stenosis.Results    In all patients, LA dimension above the median (≥43 mm) was associated with a significantly higher risk of death [HR 1.79 (CL 1.06-3.03)] and a LA volume above the median of 80 ml was associated with a significantly higher risk of death [HR 2.44 (CI 1.12-5.33)]. The presence of atrial fibrillation was significantly associated with a higher risk of death (p <0.0001). The presence of atrial fibrillation [HR 1.69 (CI 1.02-2.86)], lower left ventricular ejection fraction [HR 1.23 (CI 1.04-1.45)], higher NYHA heart failure class [HR 4.15 (CI 1.40-13.20)] and renal failure [HR 2.10 (CI 1.31-3.56)] were independent risk factors of death in patients in aortic stenosis.Conclusion    The size and volume of the LA and the occurrence of atrial fibrillation are important risk factors for death in patients with aortic stenosis. The presence of renal dysfunction, low left ventricular ejection fraction, high NYHA functional class and atrial fibrillation are independent risk factors of poor prognosis in patients with aortic stenosis.
Comparative analysis of diagnostic accuracy between MRI and CT scans in detecting skull base ENT pathologies
Authors: Iqbal A. , Khursheed S. , Ibrahim M. , Ali R. , Munir S.B. , Khan T.H. , Lodhi K.
Published: December 2023

Skull base ENT (Ear, Nose, and Throat) pathologies present a diagnostic challenge due to their intricate location. Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scans are commonly used diagnostic tools for detecting these pathologies. This study aims to associate the diagnostic exactness of MRI and CT scans in detecting skull base ENT pathologies. Aim: The primary objective of our current research is to assess and associate the diagnostic accuracy of MRI and CT scans in detecting skull base ENT pathologies, including tumors, infections, and congenital anomalies. Methods: Researchers led the retrospective study of medical records from the cohort of patients with suspected skull base ENT pathologies who underwent both MRI and CT scans. Imaging reports were reviewed by experienced radiologists blinded to the clinical outcomes. Diagnostic accuracy metrics, including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), were calculated for each modality. McNemar's test was utilized to assess statistical significance of differences in diagnostic accuracy between MRI and CT. Results: An overall of 150 individuals were involved in our research. MRI demonstrated a sensitivity of 87%, specificity of 92%, PPV of 85%, and NPV of 93% in detecting skull base ENT pathologies. CT scans showed a sensitivity of 72%, specificity of 78%, PPV of 70%, and NPV of 80%. The diagnostic accuracy of MRI was significantly higher than that of CT for detecting these pathologies (p < 0.05). Subgroup analyses were performed for different types of pathologies, providing valuable insights into the strengths and limitations of each imaging modality. Conclusion: This comparative analysis highlights the superior diagnostic accuracy of MRI over CT scans in detecting skull base ENT pathologies. MRI offers higher sensitivity and specificity, making it a valuable tool for clinicians in the evaluation and management of individuals with these conditions. However, CT may still have a role in specific cases where MRI is contraindicated or for initial screening. Clinicians should consider these findings when selecting the most appropriate imaging modality for patients with suspected skull base ENT pathologies.
Molecular and epidemiological study of pseudomonas aeruginosa isolated from burn patients in Baghdad city-Iraq
Authors: Hilal H.A.
Published: December 2023

Pseudomonas aeruginosa is rod-shaped with Gram-negative pathogens. It causes disease in humans and animals. P. aeruginosa interferes with the burn cure rates and can lead to increased death among the patients. The current study aims to detect pseudomonas aeruginosa isolates using the classical biochemical methods and polymerase chain reaction technique after isolating pseudomonas aeruginosa from burns cases in Baghdad-Iraq. A sterile swab takes Fifty samples randomly from Al-Yarmouk Teaching Hospital and Kadhemia Hospital. All samples were inoculated on rich media and then submitted to staining by gram stain and the biochemical tests (lactose fermenter, oxidase, and catalase….). The positive samples for biochemical tests are submitted to the PCR test for confirmation diagnosis. All the data related to age and gender are recorded to determine the epidemiological aspects. The findings demonstrate that the percentage of p. aeruginosa in burn cases using biochemical testing was 17/50 (34%), and the percentage of p. aeruginosa isolates from burn samples using the PCR technique was 13/17 (76.4%). In addition, the percentage of P. aeruginosa isolates using PCR in the males was 8/13 (61.5%), while the percentage of p. aeruginosa isolates using PCR in the females was 5/13 (38.4%). The infection percentage in the age groups (1-10), (11-20), (21-30), (31-40), and (41-50) years were (7.6%), (7.6%), (7.6%), (30.7%), and (46.1%), respectively. The conclusion is that PCR is an accurate method for detecting Pseudomonas aeruginosa. Pseudomonas aeruginosa infection is occurring higher in burn males than in burn females. Pseudomonas aeruginosa infection occurs more in the elderly than in young children.
A MODERN APPROACH TO DISEASE MODELING FOR THE DEVELOPMENT OF ONCOLOGY DRUGS
Authors: Khokhlova V.A. , Bezborodova O.A. , Trunova G.V. , Plotnikova E.A. , Morozova N.B. , Plyutinskaya A.D. , Vorontsova M.S. , Venediktova Yu.B. , Nemtsova E.R. , Pankratov A.A. , Shegai P.V.
Published: December 2023

Oncological diseases are characterized by the complexity of pathogenesis and demonstrate a number of specific signs, such as uncontrolled proliferation, stimulation of angiogenesis, activation of invasion and metastasis. Molecular genetic testing to examine genetic abnormalities in tumor cells has been increasingly using in oncology. With an accumulation of the data on the repertoire of mutations or other events in the patient’s tumors, new goals for the development of more targeted and specific antitumor therapies appear. For example, membrane proteins EGFR, HER-2, PSMA and C-met are identified as such targets. Despite the large volume of research conducted, no more than 11% of the total drug candidates are approved by regulatory authorities for clinical use. This is often due to their lack of effectiveness and the incomparability of the results obtained in preclinical trials in animal models with actual results in patients. Therefore, the development of experimental approaches for modeling tumor processes in laboratory animals is an urgent problem.
MicroRNA miR-204-5p IS A REGULATOR OF APOPTOSIS IN DACARBAZINE-RESISTANT MELANOMA CELLS
Authors: Palkina N.V.
Published: December 2023

Therapy for skin melanoma in its disseminated form is ineffective, among other things, due to the development of tumor cell resistance, mediated by various mechanisms. The acquisition of a stable cell phenotype is associated both with genetic and epigenetic changes mediated by the regulatory non-coding microRNA molecules.
MOLECULAR CELLULAR EFFECTS BY PROTON AND γ-IRRADIATION IN THE B16 MURINE MELANOMA MODEL IN VIVO
Authors: Yakimova A.O. , Matchuk O.N. , Selivanova E.I. , Gusarova V.R. , Mosina V.A. , Koryakin S.N. , Zamulaeva I.A.
Published: December 2023

Proton and photon (γ-) radiation is widely used in modern clinical practice for the treatment of malignant tumors of various locations. The relative biological effectiveness (RBE) of accelerated protons is about 1.1, as follows from the results of experimental studies of clonogenic survival of tumor cells in vitro. But however, despite the low RBE of proton radiation, a number of clinical studies have shown a significant increase in relapse-free and overall survival of patients after proton therapy compared with that after standard radiotherapy using photon radiation. The mechanisms, on which the differences recorded in vivo are based, are of significant scientific and practical interest, but have been poorly studied.
SYSTEMIC MECHANISMS OF DEVELOPMENT OF THE NONSPECIFIC ADAPTATIONAL REACTIONS AND ANTI-TUMOR RESISTANCE
Authors: Zhukova G.V. , Shikhlyarova A.I. , Frantsiyants E.M. , Kaplieva I.V. , Gudtskova T.N.
Published: December 2023

It is known about numerous regulatory disorders in the body during the development of a malignant process. However, in this case, the natural mechanisms of the anti-tumor resistance remain poorly understood. The concepts on the systemic processes during the development of general nonspecific adaptational reactions of the body (AR): stress and anti-stress ARs, discovered by G. Selye and Russian scientists L.Kh. Garkavi, E.B. Kvakina and M.A. Ukolova, have contributed to the development of effective technologies for preventive and complementary therapy for the purposes of clinical oncology.
Scholars’ Searching for Audio-Visual Information in Archives
Authors: Borlund Pia , Pharo Nils , Liu Ying-Hsang
Published: December 2023

This paper contributes insights into scholars’ information searching in audio-visual archives, more specifically in relation to postcolonial research projects. The paper introduces the concept of information needs based on the framework by Ingwersen. Further, the paper addresses the scholars’ search strategies and the search challenges they experienced. Insights are obtained via in-depth interviews with six scholars. The scholars adapt collection-specific search strategies and make extensive use of keyword searching. The study demonstrates the complexity of searching archives for information and how demanding searching is with respect to requiring domain knowledge, artefactual literacy, and archival intelligence. Finally, the importance of access to the expertise of archivists is confirmed.
Archives, Mismatches, Hacks! Overcoming Archival Boundaries in Transnational Research
Authors: Jensen Helle Strandgaard
Published: December 2023

In this article, I use my experiences in writing about the transnational history of Cursive to point toward ways forward for researchers interested in investigating entangled European broadcasting histories. I will point to places where I found European interconnections in journals, committees, and festivals and consider what the availability of these published and unpublished sources has meant for my inquiries. I will also explain how I used a specific content-management software (Tropy) to ‘hack’ and go beyond the national boundaries encoded in the archival collections I used. Finally, I suggest that perhaps it is not audiovisual material broadcasting archives first and foremost need to make available in digital formats if we want to further boundary-crossing television history; instead, I believe that the possibility of sharing self-digitized printed material should be a particular focus in the future.
SOSYAL MEDYA PAZARLAMASININ MÜŞTERİ DEĞERİNE ETKİSİNDE MÜŞTERİ DENEYİMİNİN ARACILIK ROLÜ VE ÜRÜN İLGİLENİM DÜZEYİNİN FARKLILIĞI ÜZERİNE BİR ARAŞTIRMA
Authors: ERZURUMLU Sibel
Published: December 2023

Sosyal medya, markalar ile tüketiciler arasında günümüzde çok etkili bir iletişim alanı olup pazarlama faaliyetleri, önemli düzeyde bu alana yönlenmiştir. Markalar, sosyal medya pazarlama faaliyetleri ile bu platformda yarattıkları etkileşim ile müşteri değeri yaratmak üzere strateji geliştirmektedirler. Bu süreçte müşteri deneyiminin de, müşteri değeri yaratmada önemli bir pazarlama kavramı ve uygulaması olduğu literatürde yer alan araştırmalarda görülmektedir. Tüketicilerin ürün ile ilgili bilgilenme ihtiyacını ifade eden ürün ilgilenim düzeyi, bu çalışma kapsamındaki araştırmada değerlendirmeye alınmıştır. Ürün ilgilenim düzeyi düşük olarak kalem pil, yüksek olarak akıllı cihaz seçilmiş; cevaplayıcılardan alınan verilerin analizi bu sınıflandırmayı desteklemiştir. Bu çalışmanın amacı, farklı ürün ilgilenim düzeyine sahip ürünlerde sosyal medya pazarlamasının müşteri değerine ve bileşenlerine etkisini ve bu etkide müşteri deneyiminin aracılık rolünü ortaya koymaktır. Araştırma bulguları, ürün ilgilenim düzeyi düşük ve yüksek her iki ürün için sosyal medya pazarlamasının müşteri değerine anlamlı düzeyde olumlu yönde etkisi olduğunu ve müşteri deneyiminin aracılık rolünün de bulunduğunu göstermektedir.
Prevalence of mask associated dry eye disease symptoms among health care workers during COVID-19 pandemic in Puducherry, India
Authors: Kalaiselvi Ganapathy , Selvaraj Vennila , Thangaraju Dharmeswari
Published: December 2023

The aim of this cross-sectional study is to measure symptoms of mask-associated dry eye disease symptoms among health workers during the COVID-19 pandemic.

This was a cross-sectional study which included Health care workers willing to participate in the Questionnaire based study from March 2022 to May 2022. After initial consent participants completed the questionnaire on the duration of mask wear, type of mask, presence and the severity of Dry Eye Disease (DED) symptoms.

A total of 930 completed data had been analyzed. Out of them 651(70%) had reported to have DED symptoms either sometimes or often. About two-third 65% (605) health care workers were in the age group of 18 to 29 years, 55% (465) had been using face mask between 4 to 8 hours per day. Less than a quarter 20% had reported to be having previous dry eye symptoms. Among them 68% (126) reported worsening symptoms. Almost half 45% wore spectacles, among them 72% reported fogging of their glasses while wearing mask. Age group 18 to 29 years were reported to have significant association with DED symptoms along with usage of N95 mask and male gender using Chi square test (P <0.001).

Our study reported ocular discomfort in majority of Health care workers who are in the fore front in this Covid-19 pandemic for long hours, hence counseling of proper wearing of face mask and ocular treatment as and when needed to maintain their ocular surface health by consulting ophthalmologist is recommended.
Challenges faced by ophthalmologists during COVID-19 era
Authors: Reddy Prajwalli , Deshpande Sumeet , Mishra Shreya , Reddy Swathy , Fatima Zeba
Published: December 2023

Aim of this study was to assess the different difficulties North Karnataka's ophthalmologists encountered during the COVID-19 pandemic.

A online questionnaire was prepared to evaluate the various difficulties faced by the ophthalmologists following the lockdown period in their respective practice areas. Data was collected from the responding ophthalmologists on Google forms and analyzed using SPSS software.

A total number of 160 responses were obtained. Most of them (32.59%) were in the age group 40–50 years and were working in private practice (35%). 78.12% of ophthalmologists returned to performing surgical procedures after a gap of more than a month post-lockdown. 38.12% of the participants reported a decrease in their surgical workload of more than 90% within this time frame. Significant fear of getting infected with COVID-19 in the operation theatres was reported. 65.65% of participants used N-95 masks while working. Revenue generation was affected significantly during this lockdown.

: It is quite evident that the eye care practitioners have been affected significantly, with patient and staff safety being the major concerns.
Lens induced glaucoma – Clinical profile and prognosis in tertiary care centre
Authors: Kulkarni Vinuta Mohan , Sultana Nishat , Abid Abdul Rauf
Published: December 2023

Conditions in which cataractous lens and abnormalities of lens leads to elevated intra ocular pressure have been termed as Lens induced glaucoma (LIG). Objective of our study was to know the clinical profile of patients, describe management and visual outcome in lens induced glaucoma.

Hospital based prospective study conducted on 40 patients of LIG from November 2016 to October 2018 attending the outpatient department of Ophthalmology at Minto Ophthalmic Hospital, Bangalore Medical College and Research Institute. After taking informed consent, detail history, detailed examination, IOP by Applanation tonometry, Gonioscopy, examination of posterior segment, patients diagnosed as lens induced glaucoma admitted and managed with medical and surgical treatment. Post operative day 1 visual acuity and IOP recorded and followed up on day 8 and 6 weeks for above. Data analyzed with descriptive statistics and chi square test.

In our study mean age of presentation in phacomorphic glaucoma is 67.25 ± 6.58 years and phacolytic glaucoma mean age was 64.10years ± 9.78. Female to male ratio being 1.8 : 1. Phacomorphic glaucoma was found in 57% and phacolytic glaucoma in 43%. Mean IOP at presentation was 42.6mmHg ±5.36. Most of them underwent SICS + PCIOL (52.5%). Study showed that most of them had better visual acuity at the end of 6 weeks. Final IOP was 15.8 mmHg± 1.78.

Our study demonstrated that lens induced glaucoma is still a challenging complication of cataract which can be prevented by early treatment of cataract. SICS is still gold standard that effectively controls IOP and gives better visual outcome.
BOCHA ADAPTADO NO SERTÃO DA PARAÍBA
Authors: Pereira Guilherme Vasconcelos , De Medeiros Sara Soares , Amorim Lilyane Dias de Medeiros , Neto Ademar Rodolfo , Nóbrega Ítalo Roberto Oliveira
Published: December 2023

O presente estudo teve como objetivo relatar a experiência dos autores na condução de um projeto de extensão realizado com indivíduos com Transtorno do Espectro Autista (TEA) e pessoas com vários tipos de deficiência física, por meio de atividades físicas com a prática do jogo do bocha adaptado, objetivando melhorar suas qualidades físicas e suas potencialidades, incutir valores na formação de sua personalidade, qualidade de vida, além de reduzir possíveis efeitos negativos trazidos pela pandemia de Covid-19, oportunizando a socialização entre os participantes, os parceiros sociais, os membros da equipe (coordenação, bolsista, estagiário e voluntários) e familiares dos participantes. Tendo como parceiros sociais o município de Patos-PB, uma Associação Civil do município e um parceiro social informal. Foi feito o mapeamento dos discentes das escolas e pacientes da APAE com perfil para a prática do bocha. As atividades do Projeto foram realizadas de julho de 2022 a janeiro de 2023. Durante esse período os participantes puderam vivenciar práticas que contribuíram para a melhora da coordenação motora, autoestima e autoconfiança. Ademais, os membros do projeto vivenciaram a significatividade de perceber o quanto as pessoas com deficiência podem desenvolver as suas potencialidades quando lhe são ofertadas oportunidades para isso.
Socjalizacja a preferencje muzyczne. Czy kiedyś zabraknie chętnych na koncerty muzyki klasycznej?
Authors: Kaczmarek Stella
Published: December 2023

Rozwój nowych mediów, obserwowane starzenie się publiczności uczestniczącej w koncertach muzyki klasycznej i stan polskiego szkolnictwa muzycznego na nowo stawiają przed nami pytanie tak o teraźniejszość, jak i o przyszłość muzyki klasycznej. Mimo że dostęp do różnego rodzaju koncertów jest niemal nieograniczony, a oferta bardzo atrakcyjna, regularnie zmniejsza się liczba słuchaczy muzyki klasycznej, zwłaszcza w krajach Europy zachodniej, ale także w Polsce, a średnia wieku słuchaczy znacząco wzrasta. Rozmijanie się oferty z liczbą słuchaczy może doprowadzić w dwóch następnych dziesięcioleciach do drastycznych zmian w preferencjach muzycznych polskiego społeczeństwa.

W artykule są przedstawiane dane z XXI wieku dotyczące słuchalności koncertów muzyki klasycznej (i podobnych form muzycznych) w Polsce i porównawczo w Niemczech – statystyki dotyczące liczby koncertów, liczby słuchaczy oraz przyszłości rynku koncertowego. Ważnem aspektem omawianym w artykule jest analiza bezpośredniego związku obecności muzyki klasycznej w życiu człowieka i jej percepcji z wczesną socjalizacją muzyczną.
Język na muzycznych pograniczach. Wokół nazwy zespołu Emerson, Lake & Palmer
Authors: Marcinkiewicz Radosław
Published: December 2023

Artykuł dotyczy perspektyw oglądu artifonimu Emerson, Lake & Palmer. Nazwa ta, sprawiająca na pierwszy rzut oka wrażenie zwyczajnej i niezbyt oryginalnej, w rzeczywistości zaskakuje bogactwem wariantów oraz pewnym potencjałem onimotwórczym. Choć zastosowany schemat nazewniczy, dość rzadko wykorzystywany w rocku, jawił się jako uniemożliwiający zmianę składu zespołu, okazał się punktem wyjścia do wykazywania się znakomitą inwencją w podejmowaniu kolejnych decyzji nazewniczych przez muzyków grupy i ich współpracowników. W artykule zwrócono też uwagę na inne kwestie dotyczące onomastyki muzycznej, m.in. zakres badań oraz adekwatność terminu proponowanego dla tej subdyscypliny, delimitację artifonimów i tytułów albumów fonograficznych, relacje transonimiczne między nazwami własnymi należącymi do tych kategorii i tendencję do tworzenia swoistych konstelacji nazewniczych (obejmujących także inne kategorie onimów muzycznych), a także zróżnicowane sposoby funkcjonowania tych onimów w języku. Dopiero odwołanie się do szeroko zakrojonych badań w zakresie etiologii onimów muzycznych powinno stanowić punkt wyjścia do ich adekwatnego i systematycznego opisu słownikowego.
The Lost Object of Love? The Mystery of Unperformed Mourning in Marilynne Robinson’s Housekeeping
Authors: Rusiłowicz Kamil
Published: December 2023

The article investigates Marilynne Robinson’s debut novel Housekeeping in an attempt to uncover the origin of the book’s melancholy. Following Sigmund Freud’s insight about the lost object of love and combining Abraham and Torok’s and Kristeva’s writings on melancholy, the text argues that the Foster women’s overwhelming melancholy may be attributed to three factors: the grandfather’s death, creating the rupture in the symbolic order; the grandmother’s unperformed mourning, which failed to mend that rupture; and the house’s progressing decay—a constant reminder of the gap between the semiotic and the symbolic.
Edukacja historyczno-kulturalna i regionalna w XX-wiecznych powieściach o Sebastianie Fabianie Klonowicu
Authors: Uljasz Adrian
Published: December 2023

Przedmiotem artykułu są trzy powieści o wybitnym polskim poecie doby renesansu i mieszczaninie z Lublina Sebastianie Fabianie Klonowicu (ok. 1545–1602). Klonowic pisał i publikował poezję w dwóch językach — po łacinie i po polsku. Książki Lucyny Sieciechowiczowej Moralista i waganci (1958 r.) oraz Za Krakowską Bramą (1960 r.) zostały opublikowane z myślą o dzieciach i młodzieży jako odbiorcach. Powieść biograficzna Danuty Bieńkowskiej Żywot szczęśliwy Sebastiana Klonowica (1965 r.) jest skierowana do czytelników młodzieżowych i dorosłych. Artykuł dotyczy wymienionych utworów i ich edycji jako przykładów przekazu edukacji historyczno-kulturalnej — regionalnej (tematyka lubelska, a także zamojska) i zarazem ogólnopolskiej w literaturze.
Ślady Arystotelesa w przestrzeni publicznej w Polsce
Authors: Rewera Mirosław , Nowakowski Piotr T.
Published: December 2023

Autorzy artykułu podjęli próbę odszukania śladów Arystotelesa w przestrzeni publicznej w Polsce. Artykuł ma charakter socjologiczno-filozoficzny z komponentem pedagogicznym. W warstwie socjologicznej opisano kwestię przestrzeni publicznej i jej cechy. Następnie dokonano wskazania śladów Arystotelesa występujących w rodzimej przestrzeni publicznej. Na koniec poddano dyskusji zebrane dane i sformułowano stosowne wnioski.
Keparahan Penyakit Tungro dan Preferensi Wereng Hijau terhadap Berbagai Dosis Pemupukan Nitrogen
Authors: Gunawan Achmad , Purwono Purwono , Lubis Iskandar , Widiarta I Nyoman
Published: December 2023

The severity of disease symptoms is affected by triangular interactions between pathogens, hosts, and the environment. This study aims to describe the severity of tungro disease symptoms concerning the resistance of rice varieties and various fertilization rates. The research used the potting method in the Center for Rice Research, Sukamandi greenhouse. The experiment was designed using a Randomized Design, with 3 varieties: Ciherang (sensitive), IR 64 (green leafhopper resistance), and Inpari 36 Lanrang (virus resistance) as the main plot, and 4 levels of combination fertilization: (1) compound fertilizer + without urea; (2) compound fertilizer and urea 250 kg/ha; (3) compound fertilizer and urea 350 kg/ha; and (4) compound fertilizer and urea 500 kg/ha, as subplots. The data was processed using Anova and Duncan's multiple distance test. The results showed that rice variety significantly affected vector preference and the severity of tungro symptoms. The dose of nitrogen fertilization does not give different results to the preferences of insects and the severity of tungro in the greenhouse. There is no interaction between the variety and the dose of fertilizing. Resistant varieties are less preferred by green leafhoppers than the sensitive varieties.

 

Keywords: antixenosis, Nephotettix virescens nitrogen fertilizer, preference
Respons Tanaman Padi Pada Media Tanam Tanpa-Tanah Berbasis Irigasi Berselang
Authors: Tirto Wahyu Widodo  , Damanhuri Damanhuri , Ilham Muhklisin  , Budiarti Sonia , Dian Agustina
Published: December 2023

Rice cultivation without land as an urban farming method is carried out to produce food in a subsistence manner. This experiment aimed to examine the response of rice plants to non-soil planting media based on alternate wetting-drying irrigation. This work was conducted at the screen house in Sumberjeruk Village, Jember Regency (8°07'42.9" S and 113°47'09.3" E) from January to May 2022, using a factorial, fully randomized design of 2-factors with 3-replications. The planting medium without soil (husk:water) as the first factor consists of 4 compositions (v/v): 0:1, 1:4, 1:6, and 1:8 (total volume of 25-L media), while variety as the second factor consists of Inpari 46 and IR 64. The results showed that the combination treatment (husk: water) 1:6 and Inpari 46 had a significant effect on the number of productive tillers (25.17 stems) and grain weight per hill (34.07 g). The planting medium of non-soil husk: water 1:6 gave no significant value to husk: water 1:4 on the total number of grains (124.21 grains) and full grains (83.52 grains). The Inpari 46 varieties showed the highest value for the total number of grains (133.07 grains), the number of full grains (84.88 grains), and the weight of 1000-seeds (22.43 g). The application of husks and water as a planting medium with the right ratio is an ideal medium for landless rice cultivation since it can supply oxygen to the media.   Keywords: growth, production, rice, subsistence farming, soilless
Ekonomi Sirkular dalam Pengelolaan Sampah Organik Menggunakan Lalat Tentara Hitam
Authors: Bahtiar Rizal , Kamelia Kamelia
Published: December 2023

The problem of organic waste can be solved by applying circular economy principles, namely in waste management using black soldier fly (BSF) maggots. These larvae can decompose organic waste into compost that can be used in agricultural activities. The results of adult larvae can be used as feed in livestock and fish because they contain high protein. The objectives of this study are (1) to identify the amount of organic waste absorption with BSF larval farming business, (2) to analyze the financial feasibility of cultivation in BSF Maggot Cultivation business units in Balaraja and in Tunas, (3) to analyze business efficiency in animal husbandry and fisheries through a circular economy system in the use of BSF larval feed. The research used descriptive-quantitative analysis, financial feasibility analysis, and business efficiency analysis. The results showed that the amount of waste absorption from larval farming business activities reached 430.7 tons/year, with the total land area needed for cultivation being 137,855 m2. The results of the business financial feasibility study show that the Tunas and Balaraja Units are feasible because they have met the eligibility criteria for NPV > 0, Net B/C > 1, IRR > interest rate, and PP > the life of the project. Business efficiency proves that fisheries and livestock business activities integrated into BSF larval cultivation are more efficient in spending on the cost of commercial feed used and provide higher profits in their businesses.

 

Keywords: business efficiency, BSF, circular economy, financial feasibility, maggot black soldier fly, organic waste
Pengembangan UMKM Olahan Pangan di Provinsi Gorontalo Menggunakan Pendekatan Sistem Dinamik
Authors: Zubedi Faradiba Faruk , Baga Lukman Mohammad , Tinaprilla Netti
Published: December 2023

Processed food SMEs in Gorontalo Province are one of the sectors contributing to regional economic development. The government implements policies and programs to develop competitive processed food SMEs. This study aims to analyze the formulation of policies for the development of processed food SMEs, with the hope of optimizing the production and added value of these SMEs through increasing production volume and market access. This study used a quantitative approach using primary data and secondary data in the form of time series. A dynamical system method with six scenarios is used and simulated until 2045. The results showed that the best scenario for achieving the research objectives was scenario six. Scenario six is carried out by simulating business capital assistance programs as well as increasing partnerships, business legality, and digitalization simultaneously. The production volume of processed food SMEs will reach 764,352 pcs in 2045, with a market access value of 41.67%. Policies need to focus on business financing and increasing the business capacity of processed food SMEs in Gorontalo province. The results of the policy simulation can be considered in realizing the achievement of accelerating the development of competitive SMEs, as stated in the Long-Term Development Plan of Gorontalo Province.

 

Keywords: dynamic policy, Gorontalo Province, processed food, SMEs

Processed food SMEs in Gorontalo Province are one of the sectors contributing to regional economic development. The government implements policies and programs to develop competitive processed food SMEs. This study aims to analyze the formulation of policies for the development of processed food SMEs, with the hope of optimizing the production and added value of these SMEs through increasing production volume and market access. This study used a quantitative approach using primary data and secondary data in the form of time series. A dynamical system method with six scenarios is used and simulated until 2045. The results showed that the best scenario for achieving the research objectives was scenario six. Scenario six is carried out by simulating business capital assistance programs as well as increasing partnerships, business legality, and digitalization simultaneously. The production volume of processed food SMEs will reach 764,352 pcs in 2045, with a market access value of 41.67%. Policies need to focus on business financing and increasing the business capacity of processed food SMEs in Gorontalo province. The results of the policy simulation can be considered in realizing the achievement of accelerating the development of competitive SMEs, as stated in the Long-Term Development Plan of Gorontalo Province.

 

Keywords: dynamic policy, Gorontalo Province, processed food, SMEs
“Químicamente”, una experiencia investigativa con software educativo gamificado para estudiantes de grado 11
Authors: Ardila-Muñoz Jimmy Yordany , Molina-Sosa Diego Alejandro , Bernal-Ríos Diego Mauricio
Published: December 2023

Este artículo presenta los resultados de un estudio que se interesó en identificar los aportes de un software educativo gamificado, en el desarrollo del tema de hidrocarburos, a un grupo de estudiantes de grado once de una institución educativa pública del municipio de Tunja, Boyacá, Colombia. La temática fue seleccionada debido a una encuesta y una entrevista aplicadas a educandos y docentes. La aplicación fue desarrollada siguiendo la metodología Scrum, a partir de los principios del aprendizaje significativo y la gamificación. El software educativo gamificado contó con tres componentes que delinearon el trabajo en cada una de las unidades temáticas: contenido, evaluación y refuerzo. De igual forma, los educandos contaron en el software con un espacio para reconocer el avance personal y colectivo en las diversas temáticas y actividades. Los resultados reflejaron el interés de los educandos por interactuar con la aplicación, realizar preguntas sobre la temática y la aparición de comportamientos asociados con la competitividad y la solidaridad, a lo que se sumó una percepción de aprendizaje por parte de ellos. A partir de esto se puede enunciar que el softwareeducativo gamificado incide en la motivación de los educandos por aprender el tema de los hidrocarburos, en la asignatura de química.
Funcionalidad familiar y vivencias en familias pertenecientes al Ejército Nacional de Colombia
Authors: Becerra Pabón Ana Cecilia , Garzón Silva Kelly Johana , Calderón Muñoz Lesbi Jazmín
Published: December 2023

El objetivo sobre el que se basó la investigación que motivó la escritura del presente artículo fue identificar los niveles de eficacia de las vivencias y conflictos que afectan la dinámica de integración afectiva y equilibrio emocional de las familias que forman parte del Ejército Nacional de Colombia. En cuanto a lo metodológico, se trata de una investigación mixta, pues en su fase cuantitativavse realizó un estudio descriptivo y transversal, y en la cualitativa, un estudio fenomenológico. Se entrevistaron a las familias de una de las brigadas del Ejército Nacional de Colombia. Con el estudio se evidencia que el mayor porcentaje de funcionalidad familiar se encuentra en un nivel interme (47 %), en el nivel alto es del 38 % y en el bajo de 14 %. En la fase cualitativa emergieron categoríascomo : “ausencia física y emocional por parte del militar”, “trabajo del militar como prioridad única” y “adaptación de la mujer al contexto militar”. Se puede concluir que las mujeres que deciden formar una familia con un hombre perteneciente a las Fuerzas Militares deben generar todo un proceso de adaptación al contexto, como son la aprobación de las dinámicas del entorno castrense, las prescripciones y los determinismos del pensamiento convergente del espíritu militar; en ocasiones, las esposas deben renunciar a sus propios proyectos de vida para facilitar el mejor desempeño profesional y la labor que demanda el partner militar.