bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Health and Nutrition Education on Blood Pressure, Knowledge and Compliance among Hypertensive Patients in Bogor District, Indonesia: A Control Quasi-Experiment
Authors: Rahmawati Nurul Dina , Sartika Ratu Ayu Dewi , Thabrany Hasbullah
Published: May 2022

AbstractWith a high prevalence of hypertension (25.8% in 2013 and 34.1% in 2018), Indonesia currently deals with a tremendous health economic burden with the implementation of National Health Insurance (JKN).  Hypertension is known to lead to severe complications and productivity loss. This study aimed to evaluate the effect of health and nutrition education on blood pressure knowledge and compliance among hypertension patients. The study was conducted over a period of 6 months in Bogor District.  A total of 179 patients (64%) completed the study (intervention n = 88, control n = 91). Compared to the control group, patients in the intervention group showed a significant improvement of knowledge and compliance (p < 0.001), yet no significant difference of blood pressure was observed. However, there was a significant mean reduction of systolic and diastolic blood pressure between baseline and end-line by around 17mmHg and 8 mmHg, respectively by the intervention group. In conclusion, health education over 6 months was related to significant improvement in blood pressure knowledge and compliance of hypertension patients. Keywords: hypertension patients, health and nutrition education, blood pressure, knowledge, compliance AbstrakDengan tingginya prevalensi hipertensi (25.8% dan 34.1% pada tahun 2013 dan 2018), Indonesia saat ini menghadapi beban ekonomi Kesehatan yang besar dengan diimplementasikannya Jaminan Kesehatan Nasional (JKN). Hal ini disebabkan hipertensi dapat menyebabkan beragam komplikasi kesehatan yang serius dan penurunan produktivitas. Studi ini bertujuan untuk mengevaluasi pengaruh edukasi gizi dan kesehatan terhadap pengetahuan, kepatuhan, dan tekanan darah pasien hipertensi selama 6 bulan pada sebanyak 179 pasien (64%) yang berhasil menyelesaikan rangkaian studi ini (jumlah subjek pada kelompok intervensi = 88 dan jumlah subyek kelompok kontrol = 91). Dibandingkan dengan kelompok kontrol, penderita hipertensi pada kelompok intervensi menunjukkan peningkatan pengetahuan dan kepatuhan yang signifikan (p<0.001), meski tidak ditemukan perbedaan tekanan darah antara kedua kelompok. Meskipun demikian, studi ini menunjukkan adanya penurunan tekanan darah sistolik dan diastolik antara baseline dan endline masing-masing berkisar 17 mmHg dan 8 mmHg. Sebagai kesimpulan, edukasi kesehatan berkaitan dengan peningkatan pengetahuan dan kepatuhan pasien yang signifikan, meski dibutuhkan waktu yang lebih panjang untuk mengobservasi perbedaan tekanan darah antara kedua kelompok.  Kata Kunci: Hipertensi, edukasi gizi dan kesehatan, tekanan darah, pengetahuan, kepatuhan
Serum Lipid Profile Parameters as Markers of Oxidative Stress in Preeclampsia- A Case-control Study
Authors: Sakarde Apurva , John Jyoti , Ahirwar Ashok Kumar , Hardas Vaijayanti
Published: May 2022

Introduction: Many hypotheses have been postulated in the pathogenesis of preeclampsia. Among these, the theory of placental ischaemia giving rise to Reactive Oxygen Species (ROS) and thus causing oxidative stress is still being explored. This oxidative stress by the ROS may be further accentuated in the presence of hyperlipidaemia via the production of various lipid peroxidation products. Aim: To assess the serum lipid profile parameters and serum Malondialdehyde (MDA) levels in normotensive pregnant and preeclamptic patients and to study the association of deranged lipid profile with oxidative stress in patients of preeclampsia. Also, to correlate these parameters with the severity of preeclampsia. Materials and Methods: The present study was a case-control study carried out in the Department of Biochemistry, Government Medical College and Hospital, Aurangabad, Maharashtra, India, from January 2014 to October 2015. The study included 50 normotensive pregnant women (control group) and 100 preeclamptic women further grouped into 50 cases of mild preeclampsia and 50 cases of severe preeclampsia with >20 weeks of gestation. Serum lipid profile, along with markers of oxidative stress viz., serum MDA were estimated in all groups. Data were analysed applying unpaired t-test and Pearson’s correlation test among various lipid profile parameters and serum MDA levels in the two groups of cases. Results: There was no significant difference in age and Period Of Gestation (POG) at the time of sample collection between all three groups. There was a significant rise in serum Total Cholesterol (TC) (210±20 and 240±41 mg/dL in group II and group III), Triacylglycerol (TAG) (180±22 and 190±24 mg/dL in group II and group III), Low Density Lipoprotein-Cholesterol (LDL-C) (140±20 and 170±40 mg/dL in group II and group III), Very Low Density Lipoprotein-Cholesterol (VLDL-C) (35±4.4 and 38±4.8 mg/dL in group II and group III) in the study group as compared to controls. Also, the serum levels of MDA were found to be significantly increased in the study groups as compared to controls. Conclusion: Deranged lipid profile status was found to be significantly associated with oxidative stress in preeclampsia.
«ЭТА ТОРГОВЛЯ ВЕСЬМА УДОБНА И ПРИНОСИТ ОГРОМНУЮ ПРИБЫЛЬ ВАШИМ ПОДДАННЫМ И УСПОКОЕНИЕ ВАШЕМУ КОРОЛЕВСТВУ»: РУССКО-ФРАНЦУЗСКАЯ КОММЕРЦИЯ В НАРВЕ В УСЛОВИЯХ БАЛТИЙСКИХ ВОЙН 1560-х ГОДОВ, "Средние века"
Authors: Рябов С.М.
Published: May 2022

В статье рассматривается организация и состояние русско-французской торговли в Нарве в 60-е годы XVI в. в условиях борьбы государств Северо-Востока Европы за гегемонию в Балтийском регионе. На основании анализа переписки, главным образом, французского посла в Дании Шарля де Данзе с королями Франции, автор приходит к выводу об обоюдном интересе Русского государства и Французского королевства в построении и укреплении двусторонней коммерции. Доказывается, что в середине 1560-х годов происходит интенсификация французского торгового трафика в русскую Нарву, несмотря на противодействие со стороны польского и шведского королей, а затем наблюдается явное снижение коммерческой активности, связанное с освобождением шведского флота от боевых действий по окончании Северной Семилетней войны 1563–1570 гг., с последующим усилением нарвской блокады. В связи с этим делается заключение, что именно в политическом международном раскладе 60-х годов XVI в. нужно искать причины, побудившие французскую сторону искать альтернативный балтийскому маршруту путь коммерческой связи с Русским государством.
КЛИРИК И ПОГРАНИЧНАЯ АДМИНИСТРАЦИЯ: ТОМАС МАГНУС НА АНГЛО-ШОТЛАНДСКОМ ПОГРАНИЧЬЕ, "Средние века"
Authors: Бельцер А.А.
Published: May 2022

Участие представителей духовенства в управлении государствами Средневековья и раннего Нового времени давно привлекает внимание исследователей. Однако в объектив внимания попадают преимущественно представители епископата и их участие в системе центрального управления, придворной политики и дипломатических миссиях. Карьера Томаса Магнуса, клирика, никогда не занимавшего епископскую кафедру, но на протяжении нескольких десятилетий игравшего ключевую роль в управлении пограничными с Шотландией графствами, позволяет лучше представить особенности как королевской политики в англо-шотландском пограничье, так и использования клириков на королевской службе при первых Тюдорах.
ОТ ДЕМОНИЗАЦИИ К ПОЧИТАНИЮ: ЖАННА Д’АРК В АНГЛИИ XV–XIX ВЕКОВ (ОРГЕЛФИНГЕР Г. ЖАННА Д’АРК В ВОСПРИЯТИИ АНГЛИЧАН, 1429–1829. Юниверсити-Парк: Издательство университета штата Пенсильвания, 2019. 230 c.), "Средние века"
Authors: Тогоева О.И.
Published: May 2022

В статье предпринят подробный разбор первого монографического исследования, посвященного проблеме описания эпопеи Жанны д’Арк в английских источниках XV–XIX вв. Книга Гейл Оргелфингер в определенной мере заполнила важнейшую лакуну в tudes johanniques, существовавшую на протяжении нескольких столетий. В ней оказались проанализированы самые разные по жанровой принадлежности тексты: официальная переписка, хронистика, исторические сочинения, художественная проза и поэзия. На этом материале автор пытается продемонстрировать, как менялось отношение к Жанне д’Арк у ее вчерашних врагов, какими эпитетами они ее награждали, какие фигуры умолчания и выдумки использовали при описании событий Столетней войны, как аргументировали свою позицию. Несмотря на существенные недостатки, отмеченные в рецензии, появление данной монографии можно приветствовать: она послужит основой (как в источниковедческом, так и в историографическом плане) для последующих исследований предложенной проблематики.
Quality Evaluation of Gruels from Malted Sorghum- Moringa oleifera Flour Blends
Authors: Kodak E. C. , Girgih A. T. , Yusuf M. I.
Published: May 2022

Aim: In this study, moringa seed flour was subjected to treatments (boiling and roasting) and used to fortify sorghum flour (Kunun Zaki flour).

Study Design: The blend ratios of Kunun Zaki flour and Moringa seed flour were 100:0 (control), 95:5, 90:5, 85:15, and 80:20 which were subjected to standard methods for evaluation of physicochemical properties of the flours while flour samples were further processed into a gruel and subjected to sensory evaluation.

Result: The results of the proximate analysis indicated an increase in moisture, protein, fat, ash, and fibre from 9.06 – 9.34, 11.12 – 13.09, 3.64 – 5.74, 2.95 – 3.32, 7.65 – 8.24% respectively and decreased in carbohydrate (65.53 – 60.62%). The pH increased (3.90 – 4.37) while the titratable acidity decreased (0.87 – 0.68). All the phytochemicals (alkaloids, flavonoids, tannins, sterols, phenols, cyanides, and phytates) increased as the moringa seed flour was added. T The addition of moringa seed flour increased vitamins A, C, B1, B2, and B6. It also led to an increase in sodium and composite flour.
Increasing Rural-urban Migration: Policy Briefs on Rural Depopulation and Urbanization in Bhutan
Authors: Dorji Gyem
Published: May 2022

This brief aims to brief the policy responses of relevant decision makers of the Ministry of Agriculture and Forest (MOAF), Gross National Happiness Commission (GNHC) and Ministry of Labour and Human Resources (MOLHR) towards the attainment of National Population Policy in Bhutan, 2018 and goals of Bhutan Vision 2020 on growing concern of Rural-Urban migration in Bhutan. Through concise findings, the write-up justifies issues of rural and urban migration as pressure on urban centres thus, leading to depopulation in rural communities in Bhutan. Having said that, intervening with right actions will result in balanced equitable socio-economic development and regional balance thus, social problems and population imbalance in the places.
Analysis of the Unexplored Security Issues Common to All Types of NoSQL Databases
Authors: Reddy Hima Bindu Sadashiva , Reddy Roopesh Reddy Sadashiva , Jonnalagadda Ratnaditya , Singh Pallavi , Gogineni Avinash
Published: May 2022

NoSQL databases outperform the traditional RDBMS due to their faster retrieval of large volumes of data, scalability, and high performance. The need for these databases has been increasing  in recent years because data collection is growing tremendously. Structured, unstructured, and semi- structured data storage is allowed in NoSQL, which is not possible in a traditional database. NoSQL needs to compensate with its security feature for its amazing functionalities of faster data access and large data storage. The main concern exists in sensitive information stored in the data. The need to protect this sensitive data is crucial for confidentiality and privacy problems. To understand the severity of preserving sensitive data, recognizing the security issues is important. These security issues, if not resolved, will cause data loss, unauthorized access, database crashes by hackers, and security breaches. This paper investigates the security issues common to the top twenty NoSQL databases of the following types: document, key-value, column, graph, object- oriented, and multi-model. The top twenty NoSQL databases studied were MongoDB, Cassandra, CouchDB, Hypertable, Redis, Riak, Neo4j, Hadoop HBase, Couchbase, MemcacheDB, RavenDB, Voldemort, Perst, HyperGraphDB, NeoDatis, MyOODB, OrientDB, Apache Drill, Amazon, and Neptune. The comparison results show that there are common security issues among the databases. SQL injection security issues were detected in eight databases. The names of the databases were MongoDB, Cassandra, CouchDB, Neo4j, Couchbase, RavenDB, OrientDB, and Apache Drill.
Herbicide Options for Suitable Weed Management of Transplanted rice in North-Eastern Ghat Zone of Odisha
Authors: Mishra P. J. , Sahoo H. K. , Garnayak L. M. , Roul P. K. , Nagothu U. S. , Panda P. K. , Mohanty S. , Patra B. P. , Mangaraj S. , Mishra A.
Published: May 2022

A field study aimed to assess different weed management tactics in transplanted rice was demonstrated during rainy season in four villages of Ganjam district of Odisha under farmer participatory mode for two years (2019 and 2020). From the concluded research work, it was observed that application of pretilachlor (0.75 kg/ha) within 3 DAT followed by bispyribac sodium @ 25kg/ha at 25 DAT recorded the highest WCE (73.27%), grain (4186 and 4351 kg/ha) and straw yield (5349 and 5308 kg/ha). Hand weeding performed better with respect to WCE (80.1, 81.3 % at harvest) but net return (Rs. 37073 /ha, Rs. 38119 /ha) was found to be low. While Pretilachlor (0.75 kg/ha) within 3 DAT followed by bispyribac sodium (25 kg/ha) at 25 DAT recorded the highest net return (Rs. 41798/ha, Rs. 43956 /ha) and B:C ratio (1.87, 1.89) than other treatments.
Complementation of Biochemical and Physiological Assays with Functional PGPR Based Assays to Screen Potential Isolates
Authors: De Parijat , Choudhury Ashok , Panda Parimal , Hoque Anarul
Published: May 2022

The work deals with the biochemical characterization of rhizospheric isolates including Indole, Methyl Red, Voges Proskauer, Citrate test (IMViC test) based quantitative biochemical assay, PGPR properties like nitrogen assimilation (in microbes), phosphate solubilization etc. A special aspect of finding the correlation between the biochemical tests and PGPR properties were also studied. Methyl red test and tryptophanase assay (by indole test) were found to be positively and negatively correlated with phosphate solubilization. Vogues Proskeur and citrate utilization tests were negatively correlated with the phosphate solubilization. In future, these biochemical tests can be used as determining factors to identify phosphate solubilizing bacteria. Moreover, a group of bacteria was identified by the scatter plot analysis which shows low acid production with high phosphate solubilization. Lastly, we have given a new approach of screening rhizospheric bacteria based on motility on nitrogen deficient media.
Storability and Quality Attributes of Pear (Pyrus communis L.) cv. Carmen Fruits at Ambient Storage Conditions as Influenced by Foliar Application of Salicylic Acid and Calcium Chloride
Authors: Hamid Mehnigar , Ali Angrej , Kumar Amit , Sundouri Amarjeet Singh , Ahad Shabnam , Mumtaz Sumaya , Ashraf Shahida
Published: May 2022

An investigation was carried out to examine the storage behaviour and biochemical quality of pear (Pyrus communis L.) fruits cv. Carmen raised on Quince C rootstock as affected by pre-harvest foliar application of salicylic acid and calcium chloride treatments. The treatments consisted of four levels each of salicylic acid (0, 100, 150 and 200 ppm) and Calcium chloride (0, 0.20, 0.25 and 0.30 %). The experiment was laid out in Randomized Complete Block Design in factorial arrangements with three replications. The treatments were applied as a foliar spray at 3, 6 and 9 weeks after the petal fall. Control plants were sprayed with water. After harvest, fruits were stored under ambient conditions for 7, 14 and 21 days. Postharvest physiological loss in weight (PLW), rotting percentage, total soluble solids, total sugars and reducing sugars in fruits was increased. In contrast, fruit firmness, titratable acidity and ascorbic acid content decreased with an increase over storage periods. Salicylic acid @ 200 ppm and calcium chloride @ 0.30 % resulted minimum physiological loss in weight and rotting percentage. Also, salicylic acid @ 200 ppm and calcium chloride @ 0.30 % were effective in minimizing the loss of fruit firmness, titrable acidity and ascorbic acid content. In conclusion, the salicylic acid @ 200 ppm and calcium chloride @ 0.30 % were found to be effective in improving pear cv. Carmen fruits storability by reducing physiological loss in weight and fruit rotting; and maintaining the biochemical quality.
Effect of Row Spacing and Organic Manures on Growth and Yield of Barley (Hordeum vulgare L.)
Authors: Shireesha PolakantI , Singh Shikha , Babu C. Sharath , Pradeepika Neela Avani , Angel Boddu Krupa Blessy
Published: May 2022

A field experiment was carried out at Crop Research Farm, Department of Agronomy, Naini Agricultural Institute, SHUATS, Prayagraj (U.P) in Rabi 2021-2022 to study the “Effect of Row spacing and Organic manures on Growth and Yield of Barley (Hordeum vulgare L.)”. It was consisting of three combinations of Row spacing & Organic manures. The experiment laid out in Randomized Block Design which consisting of nine treatments with 18 cm+ FYM 5 tons/ ha,18 cm + Neem cake 0.8 t, 18 cm + Vermicompost 2 t, 20 cm + FYM 5 tons ha, 20 cm + Neem cake 0.8 t., 20 cm + Vermicompost 2 t,22.5 cm+ FYM 5 tons /ha ,22.5 cm+ Neem cake 0.8 t, 22.5 cm + Vermicompost 2 t. The experiment results revealed that the growth parameters and yield parameters such as plant height (79.74 cm), dry weight (19.77 g/plant), number of Tillers/m2 (449.40), number of grains/spike (25.33) and test weight (51.33 g) at harvest, significantly recorded in treatment 8 with the application of 22.5 cm+ Neem cake 0.8 t. Moreover, grain yield (5.22 t/ha), straw yield (7.95 t/ha) and harvest index (45.28%), were also recorded significantly higher in the treatment of 8 which is 22.5 cm + Neem cake 0.8 t/ha among all treatments. The row spacing along with basal application of organic manures could be a promising option for growth and yield enhancement in barley.
Ethnobotanical Survey of Plants used in the Management of Pregnancy-Related Illnesses in Parts of Edo State, Nigeria
Authors: Idu McDonald , Atoe Kenneth
Published: May 2022

Aims: For many centuries before the invention of conventional drugs plants were the drugs used for the treatment of many illness, till now it has been proven by a lot of researchers that many persons still prefer the use of herbal drugs including pregnant women. This study was carried to find out the plants used for management of pregnancy-related illnesses.

Study Design:  This was a cross-sectional study

Place and Duration of Study: The study was carried out between January and May, 2019 within five local government areas of Edo State, Nigeria, which make up Benin City.

Methodology: Ethnobotanical data were gathered through general conversations with informants in the field. Fifty people were interviewed during the course of the research. An oral interview was used to gather information, which was led by a semi-structured open-ended questionnaire within five local governments in Edo State.

Results: Respondednts identified sixteen plants for management of pregnancy-related ailments. These sixteen plants' leaves, stems, and roots were primarily used. In the Amaryllidaiea family, Allium sativum, fruits and bulbs were used, whereas in the Euphorbiaceae family, Phyllantus amarus, all plant components were utilised. The Oredo local government had the highest percentage of responders who use Alchornia cordifolia from the Euphorbiaceae family for the treatment of pregnancy-related disorders, with 80 percent agreeing to use the plant.

Conclusion: Among the 16 plants identified, the most-used were Jatropha curcas, Alchornea cordifolia, and Secamone afzelii.
Effect of Labour Scarcity on Rice Production and Yieldin Guma Local Government Area of Benue State
Authors: Pinga Esther Seember , Gomez David , Fatty Lamin K. M. , Onyemma Juliet Ogadinma
Published: May 2022

The study assesses the effects of labour scarcity on rice production and yield in Guma Local Government Area of Benue State. Survey research design was adopted; with a population of 5125 registered smallholder rice farmers, out of which 371 respondents were sampled using the multi-stage sampling strategy. The questionnaire was then used to collect data from the sample. Data collected was analyzed using Statistical Package for Social Sciences (SPPS 20.0) from which simple frequencies and percentages were presented in tables and graphs to answer the research questions. Findings indicated that scarcity of labour for rice production is caused by Farmers/Herdsmen clashes, migration due to improved education; preference for other rural jobs, drudgery of farm activities as well as lack of basic social amenities in the rural areas. The findings also revealed that labour scarcity affects rice production and yield adversely in the study area as it leads to poor rice yields, smaller sizes of rice farms, poor income, preference for other crops as well increased poverty levels.
Apresentação do Dossiê de História Política
Authors: D’Assunção Barros José
Published: May 2022

Neste Dossiê sobre História Política, procuramos abarcar interconexões diversas com outras modalidades historiográficas: aHistória Regional, a História Oral, a História das Idéias, a História da Igreja, a História da Literatura, entre outras. Os recortes também se diversificam, indo da Idade Média e da Idade Moderna aos vários períodos do Brasil República.
Onde o público e o privado se confundem: a atuação da imobiliária e a fase de implantação do município de Nova Londrina-PR (1950-1968)
Authors: Augusto Samogin Almeida Guilherme Cássio
Published: May 2022

O presente artigo analisa a forma de atuação da Imobiliária Nova Londrina Ltda, no processo de constituição do município, bemcomo as três primeiras administrações municipais. Para esta pesqu isa, são analisadas fontes orais, a partir de entrevistas com antigos moradores da localidade e discutidas com a bibliografia pertinente. Nosso objetivo é apontar como surgiu o sentimento patrimonialista na cidade, onde o público e o privado se confundem desde o início. Assim, podemos melhor compreender o cisma eleitoral de 1968 na cidade, que resultou na vitória do candidato da oposição com forte apoio popular e, posteriormente, cassado pelo governo Civil-Militar sob a acusação de subversão.
História, política e ficção: veredas de tradição e modernidade no sertão rosiano
Authors: Demetrio Everton
Published: May 2022

Este artigo tem por objetivo analisar certo episódio do romance Grande Sertão: Veredas, de João Guimarães Rosa, comumente conhecido e denominado como julgamento de Zé Bebelo, pensando-o como alegoria de momento singular da história republicana nacional, buscando refletir a respeito das convulsões político-institucionais que marcaram a passagem do Império para a República, na qual atraso e modernidade ocupavam seus papéis, encarnando respectivamente uma nostálgica ordem imperial e progressista ordem republicana. Pretende-se, enfim, compreender até que ponto o espaço conformado em Grande Sertão: Veredas alegoriza a confrontação entre as dimensões rural e urbana contrastantes na tentativa de estabelecerem sua identidade, num momento de transição política e ideológica para a nação.
As elites e os clubes esportivos em Salvador, 1899-1924
Authors: Sena dos Santos Henrique
Published: May 2022

Desde o final do século XIX, as elites, na tentativa empreender práticas culturais modernas, buscaram substituir festas religiosas, entrudos e outros divertimentos considerados desatualizados por lazeres modernos como o cinema, o footing e os carnavais europeizados. Seguindo este contexto, tal artigo pretende perceber como a fundação dos clubes esportivos em Salvador representou para as elites uma tentativa de criar novas formas e espaços de sociabilidades modernos. A partir da análise da estrutura dos clubes e dos eventos sociais organizados e protagonizados por estes, a ideia é compreender a emergência dos clubes esportivos no bojo da modernização da cidade. Ao final, oferecendo aos frequentadores um ambiente em que podiam conhecer novas pessoas, participar de confraternizações e praticar esportes, entendemos que os clubes constituíram novos espaços modernos da cidade.
Mato Grosso, a capitania fronteira: fortes e presídios na fronteira ocidental da América portuguesa
Authors: Mendes Tulux Bruno
Published: May 2022

O presente artigo apresenta de forma sintética a posição de destaque assumida pela capitania de Mato Grosso durante o curso do século XVIII, colaborando para a formação da fronteira colonial na América do Sul. A metodologia adotada para compreensão desta proposta de estudo está baseada na análise da bibliografia que discute a construção dos limites da América Portuguesa e dos documentos produzidos a partir de meados desta centúria, em especial à raia oeste de Mato Grosso. Neste sentido,este breve artigo não pretende esgotar o assunto que trata da construção da barreira militar mato-grossense, mas levantar novas hipóteses e lançar olhares para o sertão colonial na constituição dos limites nacionais.
Apresentando o dossiê “História das Mulheres”
Authors: Cristina Lopes Frazão da Silva Andreia
Published: May 2022

A despeito do grande volume de estudos já realizados, muitos aspectos relacionados à presença histórica das mulheres ainda suscitam questionamentos. O que os testemunhos do passado informam sobre o comportamento e os sentimentos dasmulheres? Como as próprias mulheres expressaram suas memórias? Qual foi o papel das mulheres nos diferentes grupos religiosos? Qual o impacto da participação das mulheres nas lutas políticas? De que forma as mulheres romperam com os costumes e as normas sociais? Como as mulheres atuaram em seus relacionamentos amorosos? Estas são algumas das questões discutidas nos artigos reunidos neste volume.
Leolinda Daltro: trajetória e memória de uma ‘missionária’ entre os ‘silvícolas’ do Araguaia e Tocantins
Authors: Maria Cunha dos Santos Paulete
Published: May 2022

A protagonista que ora apresentamos, Leolinda Daltro, possui uma trajetória singular. Para o historiador, que se depara com o corpus documental por ela codificado e publicado, constata a sua complexidade e, por acréscimo, o compromisso com suas‘Memórias’. Uma memória a um só tempo individual e coletiva, considerando o emaranhado de personagens e instituições que envolviam sua atuação de ‘missionária’. Sem a pretensão de prognosticar o verdadeiro/falso ao revisitar o documento, optamospor problematizar o pioneirismo de um programa laico de educação indígena, no norte de Goiás, hoje Estado do Tocantins, projeto este que obteve a ampla participação na sociedade nacional e regional, na virada do século XIX para o XX.
“Hommes de letres” na “corte do sertão”: João Gumes e a escrita social
Authors: De Fátima Novaes Pires Maria
Published: May 2022

Este artigo analisa a trajetória intelectual de João Gumes (1858-1930), editor do primeiro jornal dos sertões da Bahia, A Penna (1897-1930), considerando o “lugar social” (Certeau, 1982) de sua produção. Para tanto, observam-se filiações intelectuais epolíticas do autor. Nas matérias daquele jornal, Gumes posicionava-se ante a política regional e estadual, assim como sobre eventos cotidianos, possibilitando-nos entrever uma sociedade recém-saída da escravidão e diante de desafios da emergente República. Da sua “Typographia”, o jornal circulava para várias partes do Brasil. Publicava periodicamente, também ali, trechos das suas comédias-drama A Abolição, A Sorte Grande, Intriga Doméstica, além de romances, a exemplo de O Sampauleiro. Ao lado da ativa vida intelectual, exerceu em Caetité, de onde era natural, a função de escrivão da Coletoria Geral, Tesoureiro e Secretário da Intendência. O seu jornal circulava em período de fortes disputas políticas na Bahia, quando se opunham Góes Calmon e J. J. Seabra.
KIF2C affects sperm cell differentiation in patients with Klinefelter syndrome, as revealed by RNA‐Seq and scRNA‐Seq data
Authors: He Haihong , Huang Tingting , Yu Fan , Chen Keyan , Guo Shixing , Zhang Lijun , Tang Xi , Yuan Xinhua , Liu Jiao , Zhou Yiwen
Published: May 2022

Klinefelter syndrome (KS) is a leading contributor to male infertility and is characterised by complex and diverse clinical features; however, genetic changes in the KS transcriptome remain largely unknown. We therefore used transcriptomic and single‐cell RNA sequencing (scRNA‐seq) datasets from KS versus normal populations through the Gene Expression Omnibus (GEO) database to identify gene biomarkers associated with the occurrence of KS. We identified a total of 700 differentially expressed genes (DEGs) and completed Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), enrichment pathway analysis and protein‐protein interaction (PPI) network analysis. A total of four unreported KS‐related hub genes (KIF2C, MRPS2, RPS15 and TSFM) were identified. Validation of the single‐cell sequencing dataset showed that only KIF2C and RPS15 were expressed in spermatocytes and that they were differentially expressed in sperm cells. Further construction of the developmental trajectories of these two genes in sperm cells showed that the KIF2C gene showed an upward trend throughout the differentiation and development of sperm cells. In conclusion, we report here that KIF2C may be closely related to the differentiation and development of sperm cells in KS patients, which is important for revealing the molecular mechanism of KS and conducting further studies.
Tuning the Performance of Negative Tone Electron Beam Resists for the Next Generation Lithography
Authors: Lewis Scott M. , DeRose Guy A. , Alty Hayden R. , Hunt Matthew S. , Lee Nathan , Mann James A. , Grindell Richard , Wertheim Alex , De Rose Lucia , Fernandez Antonio , Muryn Christopher A. , Whitehead George F. S. , Timco Grigore A. , Scherer Axel , Winpenny Richard E. P.
Published: May 2022

A new class of electron bean negative tone resist materials has been developed based on heterometallic rings. The initial resist performance demonstrates a resolution of 15 nm half‐pitch but at the expense of a low sensitivity. To improve sensitivity a 3D Monte Carlo simulation is used that utilizes a secondary and Auger electron generation model. The simulation suggests that the sensitivity can be dramatically improved while maintaining high resolution by incorporating appropriate chemical functionality around the metal–organic core. The new resists designs based on the simulation have the increased sensitivity expected and illustrate the value of the simulation approach.
Spatially Confined “Edge‐to‐Edge” Strategy for Achieving Compact Na+/K+ Storage: Constructing Hetero‐Ni/Ni3S2 in Densified Carbons
Authors: Sun Zining , Liang Huanyu , Wang Huanlei , Shi Jing , Huang Minghua , Chen Jingwei , Liu Shuai , Tian Weiqian , Cao Haijie , Li Zhi
Published: May 2022

Transition metal sulfides (TMS) are considered as promising anodes for sodium/potassium ion batteries (SIBs/PIBs), and compositing TMS with conductive nanocarbons is an effective mitigation for improving rate performance and cycling stability. However, such a coupling strategy often decreases the tap density and therefore the volumetric energy of electrode. To achieve fast electron/ion transport and high volumetric capacity simultaneously, herein, a compact nanostructure with hetero Ni‐Ni3S2 nanoparticles embedded in a densified S‐doped carbon matrix (Ni‐Ni3S2@SC) is constructed via a spatially confined “edge‐to‐edge” strategy. Experimental and theoretical results confirm that the carbon matrix and metallic Ni nanoparticles provide fast electron transport pathways at two scales, while the abundant heterojunctions with strong electric fields promote the ion migration and Na/K adsorption. As an anode in SIBs/PIBs, the Ni‐Ni3S2@SC exhibits superior rate capability (289/197 mA h g−1 at 2 A g−1), stable cycling performance (88.1/86.2% capacity retention after 100 cycles), and exceptional volumetric capacity (1048/850 mAh cm−3 at 0.05 A g−1). The impressive energy‐power characteristics for Ni‐Ni3S2@SC anode are further confirmed in full cell batteries and hybrid capacitors. The reported spatially confined “edge‐to‐edge” strategy might be adapted to the construction of various binary and/or ternary metal sulfide dense electrodes for advanced energy storage devices.
High Air Stability and Excellent Li Metal Compatibility of Argyrodite‐Based Electrolyte Enabling Superior All‐Solid‐State Li Metal Batteries
Authors: Liu Hong , Zhu Qisi , Wang Chao , Wang Guoxu , Liang Yuhao , Li Dabing , Gao Lei , Fan Li‐Zhen
Published: May 2022

Sulfide solid electrolytes (SSEs) for all‐solid‐state Li metal batteries (ASSLMBs) are attracting increasing attention due to their ultrahigh ionic conductivity and good machinability. However, current SSEs generally suffer from inferior Li metal compatibility and poor air‐stability, which severely impede their practical applications for ASSLMBs. Herein, novel argyrodite‐based SSEs of Li6+2xP1−xBixS5−1.5xO1.5xCl are synthesized via the Bi, O co‐doping the Li6PS5Cl for the first time. By adjusting the concentrations of dopant, the optimized Li6.04P0.98Bi0.02S4.97O0.03Cl presents an ultrahigh ionic conductivity (3.4 × 10−3 S cm−1). Moreover, such electrolyte displays splendid structural stability after exposure to humid air and chlorobenzene, demonstrating admirable air‐stability and solvent‐stability. The mechanism of the enhanced air‐stability of oxide‐doped SSEs is profoundly understood by conducting first‐principles density functional theory calculations. In addition, the Li6.04P0.98Bi0.02S4.97O0.03Cl electrolyte triggers the generation of LiBi alloy at the anode interface, which plays a crucial role in reducing Li+ diffusion energy barriers and improving interfacial compatibility, leading to an ultrahigh critical current density of 1.1 mA cm−2 and splendid cyclic stability in Li symmetric cell. As a result, ASSLMBs equipped with either pristine or air‐exposed Li6.04P0.98Bi0.02S4.97O0.03Cl can deliver satisfying discharge specific capacity at room temperature.
Flexible Normally Transparent Smart Window Modulating Near‐Infrared Penetration under Ambient Conditions
Authors: Liu Yang , Zhu Wenbing , Sang Jingxin , Zhang Xing , Lee Dong Wook , Seo Dae‐Shik
Published: May 2022

Smart windows that both reversibly occlude visible light and modulate the penetration of near‐infrared (NIR) light save a great deal of energy. Here, a simple, super‐fast, electrically switchable smart window that initially reflects NIR light and then scatters it in response to thermal stimuli is designed and fabricated. Transparent polymer‐stabilized cholesteric liquid crystals (PSCLCs) are prepared by photo‐polymerizing RM 257 monomers in which the planar CLCs fully reflected NIR light (1050–1550 nm). Next, an ultra‐thin, thermotropic, W0.003V0.997O2‐doped polyvinylpyrrolidone hybrid thin layer that modulates NIR light penetration over a very broad temperature range is overlaid on the PSCLCs, and the final WVO‐PSCLCs smart window features four NIR modulation modes. Specifically, when a model wood house with three 1.5‐ × 2‐cm WVO‐PSCLCs smart windows is thermally irradiated by a 250‐W infrared light for 10 min, the internal temperature is 4.8 °C less than that of a house lacking smart windows. Flexible smart windows fabricated from polyethylene terephthalate (PET) could be bent through a radius of 15 mm without any noticeable damage, and are very resistant to external vertical pressure. The flexible WVO‐PSCLCs smart windows are versatile, and afford outstanding transparency management and modulation of NIR light penetration.
Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer
Authors: Xiao Rourou , You Lixin , Zhang Li , Guo Xichen , Guo Ensong , Zhao Faming , Yang Bin , Li Xi , Fu Yu , Lu Funian , Wang Zizhuo , Liu Chen , Peng Wenju , Li Wenting , Yang Xiaohang , Dou Yingyu , Liu Jingbo , Wang Wei , Qin Tianyu , Cui Yaoyuan , Zhang Xiaoxiao , Li Fuxia , Jin Yang , Zeng Qingping , Wang Beibei , Mills Gordon B. , Chen Gang , Sheng Xia , Sun Chaoyang
Published: May 2022

Targeting the G2/M checkpoint mediator WEE1 has been explored as a novel treatment strategy in ovarian cancer, but mechanisms underlying its efficacy and resistance remains to be understood. Here, it is demonstrated that the WEE1 inhibitor AZD1775 induces endoplasmic reticulum stress and activates the protein kinase RNA‐like ER kinase (PERK) and inositol‐required enzyme 1α (IRE1α) branches of the unfolded protein response (UPR) in TP53 mutant (mtTP53) ovarian cancer models. This is facilitated through NF‐κB mediated senescence‐associated secretory phenotype. Upon AZD1775 treatment, activated PERK promotes apoptotic signaling via C/EBP‐homologous protein (CHOP), while IRE1α‐induced splicing of XBP1 (XBP1s) maintains cell survival by repressing apoptosis. This leads to an encouraging synergistic antitumor effect of combining AZD1775 and an IRE1α inhibitor MKC8866 in multiple cell lines and preclinical models of ovarian cancers. Taken together, the data reveal an important dual role of the UPR signaling network in mtTP53 ovarian cancer models in response to AZD1775 and suggest that inhibition of the IRE1α‐XBP1s pathway may enhance the efficacy of AZD1775 in the clinics.
Cationic Covalent Organic Framework with Ultralow HOMO Energy Used as Scaffolds for 5.2 V Solid Polycarbonate Electrolytes
Authors: Liu Jie , Zhang Yuhao , Ji Haoqing , Zhang Jing , Zhou Pinxin , Cao Yufeng , Zhou Jinqiu , Yan Chenglin , Qian Tao
Published: May 2022

Solid polymer electrolytes (SPEs) have become promising candidate to replace common liquid electrolyte due to highly improved security. However, the practical use of SPEs is still restricted by their decomposition and breakage at the electrode interfacial layer especially at high voltage. Herein, a new cationic covalent organic framework (COF) is designed and synthesized as a reinforced skeleton to resist the constant oxidative decomposition of solid polycarbonate electrolyte, which can stabilize cathode electrolyte interphase layer to develop long‐term cycle solid lithium metal battery. The ultralow HOMO energy (−12.55 eV according to density functional theory (DFT) calculations), reflecting its oxidation resistance at positive potential, would be responsible for the high decomposition voltage of 5.2 V versus Li+/Li of solid polycarbonate electrolyte. Furthermore, the smooth surface of interfacial layer and inhibited decomposition reaction at cathode side is confirmed in solid LiCoO2 cell, which realizes high initial capacity up to 160.3 mAh g−1 at 0.1 C and greatly improved stability in 4.5 V class solid polymer lithium metal battery with high capacity retention over 200 cycles. This new type of high‐voltage resistant solid polymer electrolyte promotes the realization of high‐voltage cathode materials and higher energy density lithium metal battery.
Quasi‐Shell‐Growth Strategy Achieves Stable and Efficient Green InP Quantum Dot Light‐Emitting Diodes
Authors: Wu Qianqian , Cao Fan , Wang Sheng , Wang Yimin , Sun Zhongjiang , Feng Jingwen , Liu Yang , Wang Lin , Cao Qiang , Li Yunguo , Wei Bin , Wong Wai‐Yeung , Yang Xuyong
Published: May 2022

Indium phosphide (InP) based quantum dots (QDs) have been known as an ideal alternative to heavy metals including QDs light emitters, such as cadmium selenium (CdSe) QDs, and show great promise in the next‐generation solid‐state lighting and displays. However, the electroluminescence performance of green InP QDs is still inferior to their red counterparts, due to the higher density of surface defects and the wider particle size distribution. Here, a quasi‐shell‐growth strategy for the growth of highly luminescent green InP/ZnSe/ZnS QDs is reported, in which the zinc and selenium monomers are added at the initial nucleation of InP stage to adsorb on the surface of InP cores that create a quasi‐ZnSe shell rather than a bulk ZnSe shell. The quasi‐ZnSe shell reduces the surface defects of InP core by passivating In‐terminated vacancies, and suppresses the Ostwald ripening of InP core at high temperatures, leading to a photoluminescence quantum yield of 91% with a narrow emission linewidth of 36 nm for the synthesized InP/ZnSe/ZnS QDs. Consequently, the light‐emitting diodes based on the green QDs realize a maximum luminance of 15606 cd m−2, a peak external quantum efficiency of 10.6%, and a long half lifetime of > 5000 h.
Plasticized PVC‐Gel Single Layer‐Based Stretchable Triboelectric Nanogenerator for Harvesting Mechanical Energy and Tactile Sensing
Authors: Park Hyosik , Oh Seung‐Ju , Kim Daeyeong , Kim Mingyu , Lee Cheoljae , Joo Hyeonseo , Woo Insun , Bae Jin Woo , Lee Ju‐Hyuck
Published: May 2022

Triboelectric nanogenerators have garnered significant attention as alternative power sources for wearable electronics owing to their simple structure, easy fabrication, low cost, and superior power output. In this study, a transparent, stretchable, and attachable triboelectric nanogenerator (TENG) is built with an advanced power output using plasticized polyvinyl chloride (PVC)‐gel. The PVC‐gel exhibit very high negative triboelectric properties and electrically insulating PVC became an electrically active material. It is found that a single layer of PVC‐gel can act as a dielectric and as a conducting layer. The PVC‐gel based single layer of triboelectric nanogenerator (S‐TENG) creates output signals of 24.7 V and 0.83 µA, i.e., a 20‐fold enhancement in the output power compared to pristine PVC‐based TENGs. In addition, the S‐TENG can stably generate output voltage and current under stretching condition (80%). The S‐TENG can be implemented as a tactile sensor that can sense position and pressure without combining multiple elements or electrode grid patterns. This study provides new applications of power sources and tactile sensors in wearable electronics.
Charge–Discharge Mechanism of High‐Entropy Co‐Free Spinel Oxide Toward Li+ Storage Examined Using Operando Quick‐Scanning X‐Ray Absorption Spectroscopy
Authors: Luo Xu‐Feng , Patra Jagabandhu , Chuang Wei‐Tsung , Nguyen Thi Xuyen , Ting Jyh‐Ming , Li Ju , Pao Chih‐Wen , Chang Jeng‐Kuei
Published: May 2022

Transition metal high‐entropy oxides (HEOs) are an attractive class of anode materials for high‐performance lithium‐ion batteries (LIBs). However, owing to the multiple electroactive centers of HEOs, the Li+ storage mechanism is complex and debated in the literature. In this work, operando quick‐scanning X‐ray absorption spectroscopy (XAS) is used to study the lithiation/delithiation mechanism of the Cobalt‐free spinel (CrMnFeNiCu)3O4 HEO. A monochromator oscillation frequency of 2 Hz is used and 240 spectra are integrated to achieve a 2 min time resolution. High‐photon‐flux synchrotron radiation is employed to increase the XAS sensitivity. The results indicate that the Cu2+ and Ni2+ cations are reduced to their metallic states during lithiation but their oxidation reactions are less favorable compared to the other elements upon delithiation. The Mn2+/3+ and Fe2+/3+ cations undergo two‐step conversion reactions to form metallic phases, with MnO and FeO as the intermediate species, respectively. During delithiation, the oxidation of Mn occurs prior to that of Fe. The Cr3+ cations are reduced to CrO and then Cr0 during lithiation. A relatively large overpotential is required to activate the Cr reoxidation reaction. The Cr3+ cations are found after delithiation. These results can guide the material design of HEOs for improving LIB performance.
Equalizing Excitation‐Inhibition via the Ambipolar Photoresponse of Al2O3/graphene Hybrid Neuromorphic Devices
Authors: Jiang Zhiguo , Wen Weikun , Zhong Zhijian , Xia Liping , Gao Fangliang , Zhang Yong , Wu Jiang , Khisro Said Nasir , Zha Aiyun , Zha Qingbin , Chen Xinman
Published: May 2022

Intrigued by the artificial intelligence and brain‐like neural networks, the photoelectronic neuromorphic devices that can simulate synaptic functions have been attracting wide attention. However, equalizing excitation‐inhibition has been seldom artificially realized despite its fundamental feature in a biological system. In this work, an artificial synapse is proposed based on a sandwiched Ag/Al2O3/graphene/ITO photodetector. The device exhibits a special ambipolar photoresponse at the millivoltage as a result of the interfacial trapping effects. Under the coupled light and electrical stimulus, the synaptic excitatory, inhibitory signals and their recovery are emulated on a single device via the positive and negative photoresponse, respectively. Further, the biologically dynamic balance of excitation and inhibition is reproduced on a simple analogous system integrating multiple photoelectronic synaptic cells. These remarkable results provide a potential foundation for building hardware units with neuromorphic architecture to mimic the complex human brain functionalities.
RETRACTED: Application of blockchain technology based on big data analysis in sustainable agriculture
Authors: Li Hongping , Luo Jun , Zhou Guangzhu
Published: May 2022

To improve the effect of sustainable agricultural development, this paper reports on sustainable agricultural development with the support of big data technology, combines the Internet of Things technology to apply blockchain in sustainable agricultural development, and analyzes the economic effect model. Moreover, this paper proves that the introduction of third‐party logistics in the vendor‐managed inventory strategy can effectively reduce the total cost of the supply chain. Through model analysis and model transformation, the inventory transportation integration optimization problem model is decomposed into two sub‐models: the transportation scheduling model and the replenishment delivery model. In addition, this paper designs a new solution algorithm based on the genetic algorithm and builds an intelligent blockchain model. The experimental research shows that the blockchain technology based on big data analysis proposed in this paper has certain effects.
WisDM Green: Harnessing Artificial Intelligence to Design and Prioritize Compound Combinations in Peat Moss for Sustainable Farming Applications
Authors: Wang Peter , You Kui , Ong Yoong Hun , Yeoh Joe Ning , Ong Jerica Pang Qi , Truong Anh Thanh Lan , Blasiak Agata , Chow Edward Kai-Hua , Ho Dean
Published: May 2022

The substantial increase in global population and climate change, among other factors, have led to global food security and supply chain challenges. The United Nations has laid out an agenda to sustainably achieve zero hunger by 2030 as one of its sustainable development goals. However, sustainably achieving improved food yield has become a challenge as excessive use of fertilizers has also led to adverse environmental impact. To address the aforementioned challenges, WisDM Green, an artificial intelligence (AI)‐based platform that aims to pinpoint and prioritize compound (e.g., biostimulants) combinations in peat moss, is harnessed to sustainably improve the yield of Amaranthus cruentus (red spinach). In this proof‐of‐concept study, from a pool of eight compounds, WisDM Green‐pinpointed combinations (6‐benzylaminopurine/ethylenediaminetetraacetic acid iron (III) (6‐BAP/EDTA‐Fe) and humic acid/seaweed extract (HA/SWE)) achieved 26.34 ± 15.80 and 33.59 ± 14.60 increase in %Yield, respectively. The study also indicates that compound combinations may exhibit concentration‐dependent synergies and thus, properly adjusting the concentration ratios of combinations may further improve plant yield in the context of sustainable farming. An interactive preprint version of the article can be found at: https://www.authorea.com/doi/full/10.22541/au.165244695.56681780.