bluuebunny/crossref_metadata_2025 huggingface dataset:
Main indicators of food security development in period the pandemic
Authors: Kulanova D. A. , Abdikerimova G. I. , Nurasheva K. K. , Seisenbayeva Zh. M.
Published: March 2023

This article examines the economic food security of the country implies a complex, as well as a multifactorial concept, which implies a material base for the development of absolutely all other parts of state security. The provision of economic security is considered one of the key problems of the country's work, thus, as well as the appearance of numerous socio-economic difficulties in the country, in the main, is caused at the same time by the fact that the government does not develop preventive events in any way or does not fulfill them in time. The government must guarantee a reliable level of security in order to form the obligations of the internal market for the food security of the world, as well as the external stability necessary for the standard functioning of the state economy, the intensive role of the country in the international economy and increasing the competitiveness of interstate. The research methodology is based on econometric, analytical and statistical methods of analysis. The value of the research is the development of a management model for innovation processes, which will contribute to the analysis of the data obtained during research on projects proposed for investment in agriculture. The results of the study show that the innovative position of the agricultural field in the world is characterized by a significant variation in manufacturing according to years, the dominance of outdated scientific and technical structures, a low degree of productivity, as well as the unstable economic location of many agricultural producers. One with the required circumstances of the exit of economic entities of the agricultural section to a high-quality other degree of management is considered to be the creation and implementation of innovative modifications of their formation. Undoubtedly, the effectiveness of the implementation of such modifications will depend on their complexity and the level of coverage of absolutely all components that characterize the requirement for the functioning of agro-economic concepts, the material and technical basis of economic entities, as well as the corresponding organizational and economic elements. Thus, the research results show that food security plays a crucial role in maintaining and continuing human life in the world.
Problems of the development of the national innovation system of Kazakhstan and increasing its competitiveness
Authors: Abzhalelova Sh. R. , Yernazarova U. S. , Chelekbay A. D.
Published: March 2023

The national innovation system is the most important factor in achieving the competitive advantages of innovative business, provides access to the necessary resources, including financial ones, the need for which is most acute in the implementation of innovative projects. The article examines the functioning of the national innovation system, where the importance of innovation in the activities of modern enterprises is determined. The study analyzes the structure of the NIS, its functioning, and determines the activity of regional forms of the innovation system. The characteristic of the Institute for the development of methods of financing innovative developments is given. The role of ministries in financing R&D vertically and the National Agency for Technological Development and the DAMU Foundation vertically is established. They provide significant support to the development of the innovation system and increase the innovation activity of domestic enterprises. NIS infrastructure and development institutions generate and transform scientific knowledge into new technologies, products, services, as well as ensure their commercialization. The article notes that one of the main directions of state policy in the field of scientific, technical and innovative activities is the creation of specialized subjects of an innovative nature, such as technoparks, technological business incubators, technopolises, high-tech companies. The article also shows the characteristic disadvantages that are unfavorable for the development of innovation: the underdevelopment of links between university science and industry, the disconnection of the banking sector from lending to innovative processes, low innovation activity of private capital. Research methodology. The methodology is based on a comparative analysis, using the method of systematization, the method of statistical and economic analysis and synthesis, observation and collection of facts to determine the most effective ways to improve the competitiveness of the national innovation system. Based on the foregoing, we believe that business structures, sources of financing and government support directly affect the innovative development of the economy.
KEPRAKTISAN BAHAN AJAR BERBASIS KONFLIK KOGNITIF MENGGUNAKAN SOFTWARE TRACKER UNTUK MENGKONSTRUK KONSEP MOMENTUM DAN IMPULS
Authors: Fitri Atikah Dian , Mufit Fatni
Published: March 2023

Permasalahan pemahaman konsep yang rendah dalam pembelajaran fisika masih sering terjadi termasuk pada konsep momentum dan impuls. Penggunaan teknologi seperti software Tracker dalam membangun konsep pada pembelajaran fisika juga masih sangat kurang. Salah satu solusi untuk mengatasi permasalahan tersebut ialah mengembangkan bahan ajar fisika berbasis konflik kognitif menggunakan software tracker pada materi momentum dan impuls. Penelitian ini bertujuan untuk menganalisis praktikalitas produk bahan ajar momentum impuls berbasis konflik kognitif. Penelitian ini melaporkan tahap pengembangan pada model pengembangan Plomp yaitu small group evaluation (uji kepraktisan). Instrumen pada penelitian ini berupa lembar angket untuk uji kepraktisan yang dianalisis dengan teknik presentase. Hasil uji kepraktisan produk bahan ajar secara keseluruhan didapat persentase rata-rata 87,76 dengan kriteria sangat praktis. Bahan ajar momentum impuls berbasis konflik kognitif mengguakan software tracker telah praktis bagi siswa dalam hal kemudahan, daya tarik, manfaat dan efisiensi.
Peripheral Neuropathy Outbreaks in Bhutan, 2020–2021
Authors: Chhetri Vishal , Dorji Tshering , Monger Adeep , Pokhrel Hari Prasad
Published: March 2023

Thiamine (vitamin B1) deficiency can cause beriberi leading to cardiac involvement or, more commonly, peripheral neuropathy. Common causes of thiamine deficiency are alcohol use, maternal thiamine deficiency, poor dietary diversity, unhygienic food preparation, and unsafe cooking practices. This report presents an analysis of suspected peripheral neuropathy outbreaks recorded at the Royal Centre for Disease Control between 2020 and 2021. The suspected outbreaks were reported from schools and monastic institutes with the main complaints of numbness and swelling of lower limbs. Three of the four events were confirmed due to thiamine deficiency by laboratory analysis. Of 34 samples tested, 27 (79%) had thiamine deficiency, defined as a thiamine diphosphate (ThDP) level <75.0 nmol/L. The mean ThDP level was 56.5 nmol/L. There were no statistically significant differences in the average ThDP level among the patients of different age groups. Given the fact that micronutrient deficiency was established as the cause of the current peripheral neuropathy outbreaks, we recommend that the supply of fortified rice across both government and private institutes in the country be initiated. Holistic approaches should be implemented to reduce the burden of micronutrient deficiencies in the country.
PENGGUNAAN MEDIA VISUAL UNTUK MENINGKATKAN PEMAHAMAN KONSEP IRISAN BIDANG DENGAN BANGUN RUANG PADA SISWA KELAS X-A SMA NEGERI 8 KUPANG
Authors: Nurak Yosef
Published: March 2023

Mathematics is a subject that many students find difficult. This is because the abstract mathematical objects, so students are difficult to understand. Thus mathematics learning needs to be endeavored according to the cognitive abilities of students, to concrete abstract mathematical objects so that students can understand them easily. From the experience of researchers in teaching over the years, many students have difficulty understanding dimensional slices of a three especially to get up the field. For this reason, it is necessary to conduct research that aims to improve students' understanding of the concept of a slice of a field with a space structure, with the object of research being students of class X-A SMA Negeri 8 Kupang. The approach taken in this study is a qualitative approach using a classroom action research design. Implementation of the actions carried out in two cycles, the first cycle is the implementation of learning material slices of a field to get up the sketch with the media, and the second cycle of the implementation of learning material a wedge to get up the field with visual media or media-based power point presentation. The data in this study were obtained by observation, administration of questionnaires and tests to the object of research. The data obtained from observations and questionnaires were analyzed by means of qualitative analysis, while the data obtained from the tests were analyzed by means of quantitative analysis. The results showed that the students' mastery of a slice of a field with a space of >80% with an average final test result of 88.6 and 68% of students said that the use of visual media could improve their understanding in learning sliced fields with spatial shapes.
SISTEMATIC LITERATURE REVIEW : EKSPLORASI ETNOMATEMATIKA PADA KERAJINAN TENUN
Authors: Rencitia  , Putra Aan
Published: March 2023

The need to refer to culture to make it easier for students to plant mathematical concepts in understanding mathematics learning materials. One of them is weaving. This study aims to determine and analyze the Etnomathematical Exploration in weaving and its relation to mathematical concepts. The research method used is the Systematic Literatur Riview (SLR) mhetod. Data collection was carried out by reviewing all articles related to ethnomathematics in weaving that were published in the 2016-2021 period. The articles used in this study were 7 accredited national journal articles obtained from the Google Schoolar database. The results show that there are many weaving carfts that can be applied in learning mathematics, aspecially in Geometry.
PENGEMBANGAN MULTI MEDIA INTERAKTIF DENGAN MODAL SAVI (SOMATIS, AUDITORY, VISUAL DAN INTELEKTUAL) PADA PESERTA DIDIK SMP
Authors: Nati Yudiana , Ralmugiz Uke , Ambao Nikmatul Ajizah
Published: March 2023

The aim of this study was to develop multimedia interactive with savi model(Somatis, Auditory, Visual Dan Intelektuall ). Learning material here was geometry of flat side for students of junior high school. This study was research and development in ( R & N ) and teh development design using was 4D ( Devine, Design, Development, and Dessemination ). The research of this study was conducted on March until May in junior high school Muhammadiyah Kupangv with the test subject. The data were collected using validation sheets, questionary and study test. Data were analyzed quantitively, that consisted of validation practical, and effectiveness analysis. The result showed that development of mathematics learning media with 4D model that has modivied to 3D model in  this research was valid based on validation sheets from expert media and expert material and the score was 87,5%. The practikal result from students responsive questionary got practical category and the average score was 73,7%. The effectiveness of this mathematical learning media got score of 75% and effective category. Therefore, it can be consluded that the developing learning media in this study was valid, practical, and effective,  so it can be implemented in mathematics learning to improve students learning out comes.
PENGEMBANGAN PERANGKAT PEMBELAJARAN MATEMATIKA DENGAN MODEL DISCOVERY LEARNING TERHADAP HASIL BELAJAR SISWA SMP
Authors: Lopsau Atriana , Yusuf St. Muthmainnah , Ralmugiz Uke
Published: March 2023

This study aims to develop mathematical learning media with the Discovery Learning model on valid, practical and effective junior high school students' learning outcomes. This research is a Research and Development (R&D) study. The product developed ar learning media in the form of lesson plans and worksheets using the Discovery Learning model on students' mathematics learning outcomes. The R&D research design used in this study is ADDIE which consists of 5 stages, namely: Analyze, Design, Development, Implement, and Evaluate. The data collection instruments are Validation Sheet, Student Response Questionnaire and Concept Understanding Test Sheet. The data analysis techniques for the development of each learning media were in valid, practical and effective criteria. The study showed that, in terms of validity, the average of  validation learning media was 3.65 with valid criteria. In terms of practicality, based on practicality trials, it was found that the results of the students’ response questionnaire to the learning media reached an average of 88.75% and was considered practical so that it was feasible to use. As for the results of the  completeness level of the effectiveness analysis reached 80% with very effective criteria. Based on the above, it can be concluded that the development of learning media with discovery learning learning models on mathematics learning outcomes for junior High school of Muhammadiyah Kupang students was valid, practical and effective and can be used in learning.
EFEKTIVITAS PEMBELAJARAN DARING SELAMA MASA PANDEMIC PADA MATA PELAJARAN MATEMATIKA
Authors: Chika Yasika Egi Putri
Published: March 2023

Abstract
This study aims to determine the effectiveness of online learning during the pandemic. This research is a qualitative research with descriptive method. The subjects of this study were 5 grade IX students of SMP Negeri 24 Tangerang. The data collection  technique used a questionnaire questionnaire containing questions about student responses to online learning in mathematics. Data analysis in this study used descriptive statistical analysis. The results of the study are shown from the results of the calculation of the percentage of student responses to online learning in mathematics subjects is 60% with the qualification criteria "less effective". This happens because students are not motivated to participate in online learning, and when implementing online learning in mathematics there are still many problems faced by students including not all students have cellphones to carry out online learning, limited internet quota, unstable internet network, and students find it difficult to understand the material in mathematics. So, from the various problems faced by students during online learning, this is what makes the implementation of online learning less effective.
 Keywords: Online Learning, Pandemic Period, and Math.
 
Abstrak
Penelitian ini bertujuan untuk mengetahui efektivitas pembelajaran daring selama masa pandemic. Penelitian ini merupakan penelitian kualitatif dengan metode deskriptif. Subjek penelitian ini adalah 5 siswa kelas IX SMP Negri 24 Tangerang. Teknik pengumpulan data menggunakan kusioner angket yang berisikan pertanyaan respon siswa terhadap pembelajaran daring pada mata pelajaran matematika. Analisis data dalam penelitian ini menggunakan analisis statistik deskriptif. Hasil Penelitian ditunjukkan dari hasil perhitungan persentase respon siswa terhadap pembelajaran daring pada mata pelajaran matematika adalah 60% dengan kriteria kualifikasi“kurang efektif”. Hal ini terjadi karena siswa tidak termotivasi mengikuti pembelajaran daring, dan pada saat pelaksanaan pembelajaran daring pada mata pelajaran matematika masih banyak permasalahan yang dihadapi siswa diantaranya tidak semua siswa mempunyai handphone untuk melaksanakan pembelajaran daring, kuota internet yang terbatas, jaringan internet yang kurang stabil, dan siswa sulit untuk memahami materi pada mata pelajaran matematika. Maka, dari berbagai permasalahan yang dihadapi siswa selama pembelajaran daring, hal inilah yang menjadi pelaksanaan pembelajaran daring menjadi kurang efektif.
Kata Kunci: Pembelajaran Daring, Masa Pandemic, Mata Pelajaran Matematika.
Pendekatan Kopling Longgar dan Ketat dalam Penyelenggaraan Organisasi Pendidikan di Indonesia
Authors:   Universitas Negeri Yogyakarta, Yogyakarta, Indonesia, Muslihah Wa Ode
Published: March 2023

The debate about the loose coupling and tight coupling paradigms in the implementation of educational organizations has continued in the last few decades. The group that supports loose coupling is based on the view that the development of the era takes place so fast, not only linear but even exponential, skyrocketing rapidly. Educational organizations that are rigid and difficult to escape from the shackles of rules and are unable to adapt to these changes will be left behind and die. By being flexible, educational organizations are able to move quickly to make the necessary adjustments so they are not left behind. Can this anxiety be mediated? Which of the two is most appropriate in the context of education in Indonesia? This review presents a critical view of the loose/tight coupling debate and provides the best alternative taken from each positive value. Next, it will be presented its application in the context of education in Indonesia and its consequences.
Training simulators for crane operators and drivers
Authors: Akulov Artem , Zhelieznov Kostiantyn , Zabolotnyi Oleksandr , Chabaniuk Eugene , Shvets Angela
Published: March 2023

The article deals with the use issues of modern information technology for training purposes. In particular, use of simulation modelling to create a learning environment as close as possible to the real working environment. This helps speed up learning, make more practical, learn theoretical issues directly when mastering practical skills, and make the learning process more attractive and interesting for students. Moreover, a virtual working environment can be used for advanced training of employees, to improve their professional skills, master new technologies, train them to work on new and modernized equipment, assess their professional level, restore skills after a long break in the work and pass qualification exams. Information technologies can significantly reduce the cost of material support for training and eliminate dependence on large areas for staff training. To create an interactive virtual learning environment, modern gaming technologies, software modelling or, at least, simulation modelling of physical processes in equipment and the interaction of all components of the working environment, including the actions of the student, are used. It also allows testing employees in extreme working conditions and testing their skills when dealing with non standard and emergency situations, without any real danger to the health of students. The proposed solution can be used to train students and trainees, assess professional skills of those already working in the conditions of special training centers and professional retraining colleges.
The role of 18F-FDG PET/CT in the follow-up of laryngeal cancer after treatment
Authors: Petrović Jelena , Šobić-Šaranović Dragana , Milovanović Jovica , Jotić Ana , Odalović Strahinja , Grozdić-Milojević Isidora , Stojiljković Milica , Artiko Vera
Published: March 2023

Introduction: The aim of this investigation was to estimate the diagnostic performance of positron emission tomography/computed tomography using fluorine-18 fluoro-deoxyglucose (18F-FDG PET/CT) in the follow-up of post-treatment laryngeal squamous cell carcinoma (SCC) and the survival rate. Material and methods: Fifty seven patients (50 males, 7 females), mean age (68.3±6.7), with post-treatment laryngeal SCC were investigated. Indications for 18F-FDG PET/CT were: post-surgery staging, post-therapy restaging with positive/uncertain CT, follow-up, suspected recurrence on CT. 18F-FDG PET/CT findings were compared to the clinical follow-up of up to 10 years after imaging. The degree of metabolic activity was analyzed visually and semi-quantitatively using the maximum standardized uptake value (SUVmax). Results: A high accumulation of radiopharmaceutical was found in 41 (71.9%) patients who were considered true positive, physiological in 14 patients (24.5%) and only two males (3.5%) were false positive. Overall sensitivity of 18F-FDG PET/CT was 95.3%, specificity 100.0%, positive predictive value 100.0%, negative predictive value 87.5% and accuracy 96.5%. In 19 cases (33.3%) PET/CT findings significantly influenced further management of the patients. Progression-free survival (PFS) in the 18F-FDG positive group was 41.1±12.7 months. Statistically significant correlation between SUVmax and PFS was not observed (p>0.05). Conclusion: 18F-FDG PET/CT is a valuable tool for the follow-up of laryngeal SCC due to its high sensitivity, specificity, PPV, NPV and accuracy. It can influence the patients' management in a significant number of cases. Patients with negative 18F-FDG PET/CT findings had longer PFS than those with positive ones, but without statistical significance. SUVmax was not proven to be a strong predictor of patients' disease-free survival.
The relevance of cholesterol and triglycerides in pregnancy
Authors: Milinčić Miloš , Dugalić Stefan , Gojnić Miroslava
Published: March 2023

Cholesterol participates in the construction of all body cells, steroid hormones, and bile acids. Its role in pregnancy is of key importance in the form of the synthesis of hormones without which conception and pregnancy would not be possible, and later in developing the physiological functions of the fetus as well. Triglycerides as the main energy substrate serve in the normal growth and development of the fetus. Normal reference values for lipid status in pregnancy have not been established yet. It has been proven that elevated, as well as reduced values of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) participate in pathological conditions of pregnancy - gestational diabetes mellitus, preeclampsia, macrosomia, restricted fetal growth, etc. The treatment of dyslipidemia is limited due to the lack of pharmacological studies on pregnant women, as well as the teratogenic effect of anti-lipid drugs. This review article deals with the effect of cholesterol and triglycerides on pregnancy, pregnancy outcomes, prenatal and postnatal effects on the fetus, as well as current and future treatment options.
Different mechanical control of weeds under vines to reduce ecological footprint
Authors: Berk Peter , Kelc Damijan , Vindiš Peter
Published: March 2023

The purpose of the study was to investigate the alternative methods of weed control in the vineyard under 'Sauvignon' vines to reduce ecological footprint in vineyard production. Weed control was performed at the experimental site with the mechanical weed control under vines with a grass cutter, a rotating star hoe (roll hoe) and a vine trunk cleaner, while at the same time additional mulching was carried out in the belts between the rows. The ecological footprint of each production operation was estimated by including environmental impacts related to fossil-C (kg CO2/hm2 ), air, water, soil, nonrenewable, renewable, and area resources. While carrying out the mechanical control, we analysed the weed coverage, grape yield and yield loss. Grape yield was highest for weedfree control plots, followed by plots where ploughshare was used. Yield loss was lowest when using ploughshare. In addition to the weed-free plot, weed coverage was lowest when glyphosate was used. The maximum amount of CO2 is released while using rotating star hoe. At the grass cutter and vine trunk cleaner less CO2 was released. The same is with global warming potential (GWP).
Analysis of public: Private partnerships in education
Authors: Bosanac Maja
Published: March 2023

Changes in the education process indicate the increasing occurrence of the privatization of education, as well as the emergence of permeation of public and private partnerships that are supported by global education policies. Considering that in the Republic of Serbia this topic is insufficiently studied, the goal of the paper is to present public-private partnerships in their complexity, possibilities, but also the implied challenges. Also, in order to understand the specificity of public-private partnerships in education, it is necessary to present the historical development of this type of partnership, as well as its broader socio-economic framework. Twofold demands placed on modern educational institutions indicate the complexity of the situation. On the one hand, educational institutions should retain its specificity while at the same time their increasingly pronounced contribution to economic efficiency is expected, resulting in establishing cooperation between the public and private sectors. The paper presents in more details the ways of achieving public-private partnerships in education. The contribution of the paper includes the actualization of literature dealing with the topic of public - private partnership. On the basis of the studied literature, it is concluded that in the future the greatest impacts of public - private partnerships can be expected within higher education.
Parliamentarism and current systems of division of state government
Authors: Osmanlić Iljaz
Published: March 2023

Parliamentarism arose as a negation of autocracy and political omnipotence, as a restraint and rejection of the cruelty and greed of charismatic and patrimonial rulers. Monarchist absolutism has long been powerful in suppressing that more complete essential feature of parliamentarism - its emancipatory, humanistic and democratic face. Parliamentary monarchy is, historically, the first state form in which the substance of the power of the traditional state is divided into three divided and redistributed activities in its exercise, three branches of government: legislative, executive and judicial. The principle of separation of powers is still the most important emancipatory principle of the modern state. From the point of view of parliamentary democracy and political pluralism, the principle of unity and the principle of division of state power are two polarities, two completely opposite values. The application of each of these two principles is strictly dependent on certain historical, socioeconomic and political circumstances and conditions in which a particular society finds itself. Even today, many believe that the application of the principle of unity of government achieves a broader and more complete democracy. This supremacy is reflected in the obligation for the executive and judicial bodies to work according to the law, apropos implementing the general decisions of the legislative body. Certainly, one of the most important reasons in the process of developing democracy and parliamentarism is the principle of separation of powers. It is necessary for each of the three branches of government to exercise its power, so that it stops and inhibits the arbitrariness of others. When we talk about a modern state, then we primarily have in mind the application and realization of the principle of separation of powers.
La inmigración venezolana en la ciudad de Madrid
Authors: Sassano Luiz Silvana , Resino García Rosa , Mayoral Peñas Milagros , Jiménez Blasco Beatriz Cristina , Barbas Nieto Ricardo
Published: March 2023

Los venezolanos constituyen el colectivo de inmigrantes en España que más ha crecido en los últimos años, dirigiéndose a las zonas más urbanizadas del país, sobre todo Madrid, Canarias y Cataluña. El objetivo principal de este trabajo es estudiar y caracterizar el comportamiento y localización de la inmigración venezolana en la ciudad de Madrid, partiendo de la hipótesis de que las características sociales y económicas de dichos migrantes no constituyen un colectivo típico de migración como sucede con otros grupos de inmigrantes en España que migran solo por motivos económicos. La metodología utilizada combina el análisis cuantitativo de los datos estadísticos con técnicas cualitativas. Como aportación principal de la investigación se pueden destacar que las pautas de localización residencial de los venezolanos en Madrid no coinciden con las de los colectivos de inmigrantes con más presencia en la ciudad (ecuatorianos, colombianos, rumanos, marroquíes…), sino que se concentran en barrios de nordeste de la capital, junto con distritos de la almendra central como el de Salamanca.
Spatial biases in approximate arithmetic are subject to sequential dependency effects and dissociate from attentional biases
Authors: Glaser Maria , Knops André
Published: March 2023

The notion that mental arithmetic is associated with shifts of spatial attention along a spatially organised mental number representation has received empirical support from three lines of research. First, participants tend to overestimate results of addition and underestimate those of subtraction problems in both exact and approximate formats. This has been termed the operational momentum (OM) effect. Second, participants are faster in detecting right-sided targets presented in the course of addition problems and left-sided targets in subtraction problems (attentional bias). Third, participants are biased toward choosing right-sided response alternatives to indicate the results of addition problems and left-sided response alternatives for subtraction problems (Spatial Association Of Responses [SOAR] effect). These effects potentially have their origin in operation-specific shifts of attention along a spatially organised mental number representation: rightward for addition and leftward for subtraction. Using a lateralised target detection task during the calculation phase of non-symbolic additions and subtractions, the current study measured the attentional focus, the OM and SOAR effects. In two experiments, we replicated the OM and SOAR effects but did not observe operation-specific biases in the lateralised target-detection task. We describe two new characteristics of the OM effect: First, a time-resolved, block-wise analysis of both experiments revealed sequential dependency effects in that the OM effect builds up over the course of the experiment, driven by the increasing underestimation of subtraction over time. Second, the OM effect was enhanced after arithmetic operation repetition compared to trials where arithmetic operation switched from one trial to the next. These results call into question the operation-specific attentional biases as the sole generator of the observed effects and point to the involvement of additional, potentially decisional processes that operate across trials.
The effects of operator position and superfluous brackets on student performance in simple arithmetic
Authors: Ngo Vy , Perez Lacera Luisa , Closser Avery Harrison , Ottmar Erin
Published: March 2023

For students to advance beyond arithmetic, they must learn how to attend to the structure of math notation. This process can be challenging due to students' left-to-right computing tendencies. Brackets are used in mathematics to indicate precedence but can also be used as superfluous cues and perceptual grouping mechanisms in instructional materials to direct students’ attention and facilitate accurate and efficient problem solving. This online study examines the impact of operator position and superfluous brackets on students’ performance solving arithmetic problems. A total of 528 students completed a baseline assessment of math knowledge, then were randomly assigned to one of six conditions that varied in the placement of higher-order operator and the presence or absence of superfluous brackets: [a] brackets-left (e.g., (5 * 4) + 2 + 3), [b] no brackets-left (e.g., 5 * 4 + 2 + 3), [c] brackets-center (e.g., 2 + (5 * 4) + 3), [d] no brackets-center (e.g., 2 + 5 * 4 + 3), [e] brackets-right (e.g., 2 + 3 + (5 * 4)), and [f] no brackets-right (e.g., 2 + 3 + 5 * 4). Participants simplified expressions in an online learning platform with the goal to “master” the content by answering three questions correctly in a row. Results showed that, on average, students were more accurate in problem solving when the higher-order operator was on the left side and less accurate when it was on the right compared to in the center. There was also a main effect of the presence of brackets on mastery speed. However, interaction effects showed that these main effects were driven by the center position: superfluous brackets only improved accuracy when students solved expressions with brackets with the operator in the center. This study advances research on perceptual learning in math by revealing how operator position and presence of superfluous brackets impact students’ performance. Additionally, this research provides implications for instructors who can use perceptual cues to support students during problem solving.
Tisotumab Vedotin Safety and Tolerability in Clinical Practice: Managing Adverse Events
Authors: R. Arn, APRN-CNP Courtney , J. Halla, MSN, FNP-C Kimberly , Gill, RN (Hons) Sally
Published: March 2023

Tisotumab vedotin-tftv, an antibody-drug conjugate indicated for the treatment of adult patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy, demonstrated clinically meaningful and durable responses with a manageable safety profile in the pivotal phase II innovaTV 204 clinical trial. Based on the proposed mechanism of action of tisotumab vedotin, experience from clinical trials, and the US prescribing information, certain adverse events (AEs) including ocular AEs, peripheral neuropathy, and bleeding have been identified as AEs of interest. This article highlights practical considerations and provides recommendations to support the management of selected AEs associated with tisotumab vedotin. Central to monitoring of patients on tisotumab vedotin is a comprehensive care team comprised of oncologists, advanced practice providers (including nurse practitioners, physician assistants, and pharmacists), and other specialists such as ophthalmologists. As ocular AEs may be less familiar to gynecologic oncology practitioners, adherence to the “Premedication and Required Eye Care” section outlined in the US prescribing information, as well as the incorporation of ophthalmologists into the oncology care team, can help provide timely and appropriate eye care for patients receiving tisotumab vedotin.
Inscripciones de Ilici, Allon y Lucentum en un manuscrito de la Biblioteca Nacional de París
Authors: Mayer Marc
Published: March 2023

Las copias de inscripciones en un manuscrito, conservado entre los papeles de Bernard de Montfaucon en la BNF, nos permiten ver dibujos de epígrafes de Ilici, Allon y Lucentum en buena parte perdidos y constituyen una muestra del desarrollo del estudio epigráfico en la zona y de su contexto cultural.
La construcción de una prosopografía: la Vita Mahometis de Onofre Micó
Authors: Gómez Puig Jesús
Published: March 2023

Este artículo pretende analizar el fragmento dedicado a la figura de Muhammad confeccionado en clave biográfica por la pluma de Onofre Micó. La Lex euangelica contra Alcoranum de Onofre Micó se inicia con esta uita Mahometi, recurso usual en los textos cristianos de refutación de la doctrina musulmana. En estas notas, el autor trata de analizar la figura del fundador del islam y demostrar su origen impío y, en consecuencia, el de su doctrina. Por tanto, la obra se circunscribe en el ámbito de la polémica, respondiendo a las circunstancias políticas y religiosasEste  del momento.
Ab urbe condita de Tito Livio: ¿fuente directa de El robo de las sabinas, comedia en colaboración de Juan Coello y Arias, Francisco de Rojas Zorrilla y Antonio Coello Ochoa?
Authors: Gómez Caballero Iván
Published: March 2023

El presente trabajo trata de establecer un estudio comparativo y mitocrítico determinando si Ab urbe condita de Tito Livio puede ser la fuente directa de El robo de las sabinas, comedia en colaboración de Juan Coello y Arias, Francisco de Rojas Zorrilla y Antonio Coello Ochoa. Asimismo, analizamos, en primer lugar, la transmisión y la recepción textual del historiador latino en España durante el siglo XVII, pero también durante la Edad Media y el Prerrenacimiento para establecer si los hermanos Coello y Rojas pudieron tener acceso a ella. Por otra parte, desgranamos la vida de Rómulo en una serie de mitemas y comparamos los que aparecen en la comedia áurea con los de Ab urbe condita. Finalmente, extraemos una serie de conclusiones para determinar si Tito Livio puede ser, por tanto, la fuente directa de esta comedia o, por el contrario, se aleja determinantemente de los sucesos que tienen lugar en ella.
The image of the Greeks in the greek (codex H) and aragonese (Arag.) Chronicle of Morea
Authors: Kioridis Ioannis , Sourba Maria , Stratigopoulos Dimosthenis
Published: March 2023

The study examines the image of the Greeks in two of the codices of the Chronicle of Morea, the H and the Arag ., texts of the 14th century, with the lost prototype tracing back to t he start of the same century. The image of the G reeks (which are usually called Ρωμα?οι and griegos respectively in the two texts )), is directly linked with the identity of the authors a nd the targeting of the texts ? composition The author of H aligns wit h the Franks, he disp arages the Greeks of Constantinople, while exhibiting a more positive attitude about the local Greeks of Morea. He does not hesitate to distort historical reality it self in order to achieve his goals, which are praising the Villehardouins and the nostalgic reminiscing of an era that had been lost for good. On the other hand, on the Aragonese text, the author’ s stance on the Greeks and the Franks  is generally negative. He, same as before, is positive regarding the local Greeks of Morea . The author never align s himself with the Francs, which makes him more objective. He is mainly interested in the subjects that relate to the Kingdom of Aragon, while his stance is influenced by the fact that his work is completed not long after the described events, comissioned by an prominent ex administrator of Morea.
EV TEKSTİL ÜRÜNLERİ ÖZELİNDE EKİNEZYA VE EVELİK TOHUMU İLE PAMUKLU KUMAŞLARIN NANO MORDANLAR KULLANILARAK RENKLENDİRİLEBİLİRLİĞİNİN ARAŞTIRILMASI
Authors: Yılmaz Fazlıhan , Gültepe Gülten , Uygur Mariye
Published: March 2023

Ev tekstili ürünleri, popülaritelerini son zamanlarda kazanmalarına rağmen geçmişten günümüze kadar hayatımızın büyük bir alanında var olmuşlardır. Tüketiciler tarafından ev tekstili ürünlerinin tercih edilmesinde renk önemli bir faktördür. Bu faktör için ise tekstil endüstrisinde genellikle kimyasal maddelerin kullanıldığı bilinmektedir. Bu bağlamda, günümüz ev tekstil ürünlerinde yoğun olarak kullanılan pamuklu kumaşların, renklendirilme işlemlerinde kimyasal madde kullanım oranının azaltılabilmesi çalışma kapsamında hedeflenmiştir. Bunun için ise geçmiş zamanlardan beri geleneksel Türk el sanatları kültüründe yer alan doğal boyarmaddelerin kullanılması çalışmada amaçlanmıştır. Çalışma kapsamında doğal boyarmadde kaynağı olarak ekinezya çiçeği ve evelik tohumu kullanılmıştır. Tekstil mamulü olarak ise dokuma pamuklu kumaş kullanımı tercih edilmiştir. Boyama denemelerinde kullanılacak olan bitkisel kaynaklar hiçbir ön işleme tabii tutulmadan direkt olarak kullanılmıştır. Ayrıca çalışmada nano mordanlar yardımıyla da ön ve birlikte mordanlama yöntemine göre de boyama denemeleri gerçekleştirilmiştir. Yapılmış olan boyama işlemlerinden sonra boyanmış olan pamuklu kumaşların CIE L*a*b* C* ho değerleri ve K/S renk verimliliği değerleri ile birlikte sürtme ve yıkama haslık testleri de gerçekleştirilmiştir. Özellikle ekinezya çiçeği kullanılarak boyanmış pamuklu kumaşların yıkama haslığı değerleri genel olarak 5 iken evelik tohumu kullanılarak yapılmış boyama denemelerinde ise bu değer genel olarak 4-5 ve 5 olarak karşımıza çıkmaktadır. Yapılan boyama denemeleri ve ölçümler neticesinde ekinezya çiçeği ve evelik tohumunun pamuklu kumaşların renklendirilmesinde kullanılabileceği tespit edilmiştir.
FARKLI FİLAMENT SAYISINA SAHİP POLYESTER İPLİKLERİN DOKUMA ZEMİN KAPLAMALARI ÜZERİNDEKİ ETKİSİNİN İNCELENMESİ
Authors: Özdinç Öznur , Güneşoğlu Cem
Published: March 2023

Geleceğe yönelik zemin kaplamaları olarak anılmaya başlanan hafif dokuma zemin kaplamaları özellikle tozu içine hapsedecek hav tabakası bulundurmadığı için alerjenler/ev tozu akarları bulundurmazlar. Bu çalışmada atkı ipliği olarak kullanılacak polyester ipliğin filament sayısını belirleyebilmek ve bu parametrenin dokuma tipi zemin kaplamaları üzerindeki mekanik etkilerini incelemek amacı ile aynı üretim parametrelerinde numuneler ürettirilmiştir. Bu numunelerden, test numuneleri alınarak her birine sıkıştırılabilirlik ve rezilyans tayini, dinamik yük altında kalınlık kaybı tayini, uzun süreli statik yük altında kalınlık kaybı tayini, aşınma dayanımı tayini, kopma mukavemeti ve uzaması tayini testleri yapılmıştır. Çalışma sonuçlarına göre, atkı ipliği olarak farklı filament sayılarına sahip atkı iplikleri ile dokunan özdeş zemin kaplamaları dokunmuştur. İplikteki filament değeri 384 filament sayısından 96 filament sayısına düştükçe dokunun mekanik performansının arttığı görülmüştür.
INVESTIGATION OF SEAM EFFICIENCY OF DIFFERENT SEAM TYPES IN WOOLEN GARMENTS
Authors: Gürarda Ayça , Öztaş Hande
Published: March 2023

Seams are very important for the quality of woolen garments. Seams of the garment must be durable and smooth. Seam performance is an important factor determining the durability of a garment. The tensile characteristics of seamed fabric changes with the change of fabric bias angle, stitch and seam types. In this study, three wool fabrics with different properties were chosen. Fabrics have been cut in the angles 0°, 30°, 45°, 60° and 90° and then sewn with six different seam types (SSa-1/301, LSc-1/301, LSq-2/301, LSb-1/301, SSc-1/301, LSc-2/301). In these samples, the effects of different seam types at different seam angles of stitching on seam strength and seam efficiency were investigated. Results indicated that, the woolen fabrics seamed with different seam types at different angles possessed statistically different seam strength and seam efficiency values. Fabrics seamed with LSc-2 seam type give the highest seam strength and seam efficiency values and the seams prepared with 30° and 60° bias angles give the lowest seam strength values. Generally, SSa superimposed seam type is preferred in garments. As can be seen from this study, if LSc lapped seam type is used instead of SSa superimposed seam type, the seams would be more durable.
Political Science Education in the Educational Environment of University: Valuable Semantic Foundations
Authors: Dianov Sergei Aleksandrovich
Published: March 2023

Political science education over the past thirty years has become the most important element of the humanitarian sphere of the Russian university. At the same time, a discussion continues in the scientific and pedagogical community about the status of political science education in the professional training of specialists in demand for the country, masters and research teachers. One of the main questions postulated in the expert community is to determine the role of the science of politics in preventing the emergence of conflict situations in the educational space of the university on the basis of the "politicization" of the worldview positions of participants in educational relations. The transition in 2010 - 2020 to a competency-based model for the implementation of basic professional educational programs and the introduction of project technologies in the educational process led to a serious transformation of the architecture of education and upbringing at the university. The article presents arguments in favor of the author's hypothesis about the need to introduce programs of political and legal education at leading universities for all participants in the educational process. The author comes to the conclusion that the approbation of such programs will qualitatively update the content of the educational work of innovative teachers and methodologically strengthen the cultural component in the professional outlook of students. The educational component is also emphasized. The content of the programs should include didactic materials containing recommendations on how to quickly respond to typical conflict situations on the grounds of a mismatch of political orientations among the youth. The materials contained in the article are addressed to graduate students, young professionals and researchers of higher education.
Professional Author's Training Methods Computer-Graphic Modeling for Participants of the Advanced Engineering School
Authors: Dianov Sergei Aleksandrovich , Dianova Yuliya Viktorovna
Published: March 2023

The article presents a research view on the features of the organization of the process of teaching computer-graphic modeling for participants in the educational process within the framework of an advanced engineering school. It is shown that this direction is not innovative and the creative teams of university engineering schools have already gained some experience in quickly solving typical problems in the process of advanced training of a highly qualified specialist. At the same time, the authors of the article draw attention to circumstances that significantly limit the achievement of ambitious goals pursued in the implementation of pilot educational programs. The application of the participants of the advanced engineering school to bridge the gap between theory and practice looks especially declarative, given that the formation of even basic skills (spatial thinking) for many members of elite engineering training groups requires significant time costs. Today, in Russian universities, this problem is solved by traditional methodological methods as part of the teaching of the discipline "Engineering Geometry and Computer Graphics". The author's methods of teaching computer-graphic modeling outlined in the article are addressed to innovative teachers who realistically assess their capabilities when developing their own design educational products for students who have made a conscious choice in favor of an advanced engineering school. The article was written based on the results of approbation of the author's pedagogical initiatives in the educational process of the university (Perm Polytechnic University).
Machine learning aided multiscale modelling of the HIV-1 infection in the presence of NRTI therapy
Authors: Tunc Huseyin , Sari Murat , Kotil Seyfullah
Published: March 2023

Human Immunodeficiency Virus (HIV) is one of the most common chronic infectious diseases in humans. Extending the expected lifetime of patients depends on the use of optimal antiretroviral therapies. Emergence of the drug-resistant strains can reduce the effectiveness of treatments and lead to Acquired Immunodeficiency Syndrome (AIDS), even with antiretroviral therapy. Investigating the genotype-phenotype relationship is a crucial process for optimizing the therapy protocols of the patients. Here, a mathematical modelling framework is proposed to address the impact of existing mutations, timing of initiation, and adherence levels of nucleotide reverse transcriptase inhibitors (NRTIs) on the evolutionary dynamics of the virus strains. For the first time, the existing Stanford HIV drug resistance data have been combined with a multi-strain within-host ordinary differential equation (ODE) model to track the dynamics of the most common NRTI-resistant strains. Overall, the D4T-3TC, D4T-AZT and TDF-D4T drug combinations have been shown to provide higher success rates in preventing treatment failure and further drug resistance. The results are in line with the genotype-phenotype data and pharmacokinetic parameters of the NRTI inhibitors. Moreover, we show that the undetectable mutant strains at the diagnosis have a significant effect on the success/failure rates of the NRTI treatments. Predictions on undetectable strains through our multi-strain within-host model yielded the possible role of viral evolution on the treatment outcomes. It has been recognized that the improvement of multi-scale models can contribute to the understanding of the evolutionary dynamics, and treatment options, and potentially increase the reliability of genotype-phenotype models.