bluuebunny/crossref_metadata_2025 huggingface dataset:
Noninvasive Temperature Measurements in Tissue-Simulating Phantoms Using a Solid-State Near-Infrared Sensor
Authors: Kauffman Ariel , Nguyen John Quan , Parthasarathy Sanjana , Arnold Mark A.
Published: June 2024

The monitoring of body temperature is a recent addition to the plethora of parameters provided by wellness and fitness wearable devices. Current wearable temperature measurements are made at the skin surface, a measurement that is impacted by the ambient environment of the individual. The use of near-infrared spectroscopy provides the potential for a measurement below the epidermal layer of skin, thereby having the potential advantage of being more reflective of physiological conditions. The feasibility of noninvasive temperature measurements is demonstrated by using an in vitro model designed to mimic the near-infrared spectra of skin. A miniaturizable solid-state laser-diode-based near-infrared spectrometer was used to collect diffuse reflectance spectra for a set of seven tissue phantoms composed of different amounts of water, gelatin, and Intralipid. Temperatures were varied between 20–24 °C while collecting these spectra. Two types of partial least squares (PLS) calibration models were developed to evaluate the analytical utility of this approach. In both cases, the collected spectra were used without pre-processing and the number of latent variables was the only optimized parameter. The first approach involved splitting the whole dataset into separate calibration and prediction subsets for which a single optimized PLS model was developed. For this first case, the coefficient of determination (R2) is 0.95 and the standard error of prediction (SEP) is 0.22 °C for temperature predictions. The second strategy used a leave-one-phantom-out methodology that resulted in seven PLS models, each predicting the temperatures for all spectra in the held-out phantom. For this set of phantom-specific predicted temperatures, R2 and SEP values range from 0.67–0.99 and 0.19–0.65 °C, respectively. The stability and reproducibility of the sample-to-spectrometer interface are identified as major sources of spectral variance within and between phantoms. Overall, results from this in vitro study justify the development of future in vivo measurement technologies for applications as wearables for continuous, real-time monitoring of body temperature for both healthy and ill individuals.
Investigation of the Distribution and Binding Affinity of Copper to Size-Fractioned Dissolved Organic Matter (DOM) in a Constructed Wetland
Authors: Hung Ming-Yuan , Huang Wei-Hsiang , Hsu Liang-Fong , Hsieh Chi-Ying , Chen Ting-Chien
Published: June 2024

This study investigated the distribution and binding affinity of dissolved copper (Cu) and organic carbon (OC) in size-fractioned dissolved organic matter (DOM) in a constructed wetland (CW). Two sites were studied: one at the inflow (P-1) and one within the wetland (P-2). The DOMs (<0.45 μm) were separated into six size fractions using a cross-flow ultrafiltration system. In the wetland (P-2), the concentrations of dissolved organic carbon (DOC) increased while the concentrations of Cu decreased. The high molecular weight fraction (1 kDa–0.45 μm, HMW) contained most of the OC mass (57.4–71.2% averages). On the other hand, Cu was almost equally distributed in HMW and low molecular weight fractions (<1 kDa, LMW) with mean HMW percentages of 50.3–51.3%. The mean Cu binding affinity to DOM ratios (CuBADOM) was 74.9 ± 24.0 μmol/g-C at site P-1 and 17.3 ± 2.6 μmol/g-C at site P-2. The CuBADOM ratios were decreased in wetlands of bulk and size-fractioned DOM (p < 0.001 to p = 0.073). The SUVA254 values for bulk DOM solution were 2.54 ± 0.15 and 1.68 ± 0.18 L/mg-C/m, and humidification index (HIX) values were 1.74 ± 0.16 and 2.09 ± 0.19 for sites P-1 and P-2, respectively. Optical indicators suggested that the wetland process decreased aromaticity but increased the humification degree of DOM. Furthermore, the CuBADOM ratios positively correlated with SUVA254 and HIX within the constructed wetland DOM but not in the influent DOM. Understanding the Cu distribution and binding affinity to size-fractioned DOM makes it possible to develop strategies to mitigate the potential effects of copper pollution in wetlands.
Experimental Study on the Effect of Environmental Water on the Mechanical Properties and Deterioration Process of Underground Engineering Masonry Mortar
Authors: Yang Jinghu , Cheng Ye , Cui Dawei , Zhang Zewei , Zhang Bo , Chai Jiamei
Published: June 2024

Urban underground engineering is generally buried at a shallow depth and suffers long-term environmental water effects such as rainfall, rivers, underground pipeline leakage, and groundwater. The mechanical properties of the structures are affected by constant deterioration, which seriously hinders the safe, healthy, and sustainable development of the city. On the basis of on-site investigation of civil defense engineering, this article simulates the water environment conditions of mortar in underground engineering in the laboratory and conducts manual sample preparation in the laboratory. Then, water, H2CO3, NaCl, and Na2CO3 solution or wet–dry cycles are used to corrode the sample, respectively. A uniaxial compression test, Brazilian splitting test, analyses of the acoustic emission signals and electromagnetic signals, and magnetic imaging testing are performed, respectively. The results show that an increase in the action time of environmental water leads to a gradual increase in the uniaxial compressive strength, tensile strength, and elastic modulus of cement mortar, but it will decrease over a long period of time. Different environmental water components can also lead to a different performance of soaked mortar. The uniaxial compressive strength R, tensile strength σt, and elastic modulus E of mortar samples exhibit values in different solutions in the order of H2CO3 solution < NaCl solution < Na2CO3 solution < water. A moderate solution soak time can enhance the mechanical properties of the mortar, but this effect decreases at long time scales. The effect of wet–dry cycles on the mechanical properties and degradation process of mortar is significant. With the increase in wet–dry cycles, the porosity of mortar continuously increases. The cumulative ringing count, energy, amplitude, and impact number of acoustic emission signals always increase when the samples are loaded to failure. The uniaxial compressive strength, tensile strength, and elastic modulus first increase and then decrease. The experimental results lay the foundation for further investigating the performance changes in mortar under complex water environments in underground engineering.
Exploring the Landscape of Eco-Innovation: A Bibliometric Analysis of Concepts and Trends in the Manufacturing and Shipbuilding Industries
Authors: Paipa-Sanabria Edwin , Orozco-Lopez María Belén , Escalante-Torres Felipe , Camargo-Díaz Clara Paola , Zapata-Cortes Julian Andres
Published: June 2024

Eco-innovation (EI) as a conceptual approach has gained significant momentum in the transition of the manufacturing sector towards sustainability. This paper aims to contribute to the study of the research landscape on EI in the manufacturing industry by applying a bibliometric methodology and identifying prevailing trends and concepts used in academic literature. For this purpose, search engines such as Scopus and Web of Science (WoS) were utilized, along with analytical tools such as Bibliometrix, Microsoft Excel, and Gephi. The search was conducted using equations constructed from keywords deemed relevant to the objective, and the records obtained from the databases were consolidated into a single repository for joint analysis using the RStudio platform. The findings revealed an increase in scientific production from 2010 onwards. The analysis identified that the most influential authors, affiliations, and documents primarily originate from Spain, Germany, and China. The key concepts identified are the circular economy, eco-design, and green technologies, which provide a holistic framework for improving efficiency, reducing waste, and mitigating environmental impacts. EI promotes close collaboration between industries to reduce the ecological footprint. Nonetheless, there is a notable gap in research about EI in the shipbuilding industry, necessitating further exploration in the sector. This study lays a foundation for future investigations in this evolving domain.
The Biostimulation Activity of Two Novel Benzothiadiazole Derivatives in the Tomato Cultivation
Authors: Kukawka Rafal , Spychalski Maciej , Smiglak Marcin , Gaj Renata
Published: June 2024

Biostimulants are gaining more and more attention in modern agriculture. As follows from the definition, their role is aimed at influencing the plant’s metabolism, which results in increasing the quantitative and qualitative parameters describing the yield. Significant attention should be paid to biostimulants increasing the content of health-promoting substances contained in plants. Treatments with biostimulants should be properly incorporated into existing plant protection schemes, which, of course, requires detailed research in this area. However, reliable research on active substances contained in biostimulants should be made first, and the activity of a given biostimulant must be proven. This work presents the results of a field experiment in tomato cultivation for two new active substances belonging to the group of benzothiadiazoles. The results indicate a positive effect on plant yield and, above all, on the lycopene content in tomato fruits. Increasing the lycopene content in fruit is of key significance, as it opens up opportunities for these active substances to be incorporated into new plant protection programs.
A Panel Analysis on the Nexus between Financial Development, Oil Production, and Trade-Openness and Its Impact on Sustainable Economic Growth: Evidence from Selected Arab Economies
Authors: Deryag Esmail M. A. , Khalifa Wagdi
Published: June 2024

In accordance with the United Nations Sustainable Development Goals agenda for decent and sustainable economic growth highlighted in the UNSDGs-8, several economies over the years have been on the quest for drivers for decent and sustainable economic growth, of which the Arab bloc is no exception. To this end, the present study draws strength from the classical growth model while exploring the dynamic nexus between oil production and economic growth while accounting for other key growth drivers like gross capital formulation accumulation, labour, trade openness, and financial development for a balanced panel of selected Arab economies. To operationalise the study objectives, the present study leverages second-generational panel econometric approaches. The econometrics techniques applied circumvent the cross-sectional dependency and slope heterogeneity in the sampled bloc. For co-integration analysis, the Westerlund’s panel co-integration test affirms a long-run equilibrium relationship between the study’s outlined variables. Furthermore, for long-run estimates, the present study leverages the common correlated effects mean group (CCEMG) methodology and the augmented mean group (AMG) method for robustness and soundness of the results and coefficients. The present study corroborates the trade-induced growth hypothesis in the entire panel at a p < 0.001 statistical level, which resonates with the mercantilism school of thought. Additionally, the present study also affirms the Solow–Swan hypothesis, where gross capital formation accumulation and labour drive economic growth. Interestingly, the panel bloc shows that oil production is a key driver to the nation’s economic growth, at a p < 0.05 statistical level. However, from a policy standpoint, there are policy suggestions for diversification of the Arab economies to move from a mono-economy dependent on oil production to other sectors like service, industry, and manufacturing, which require labour, capital accumulation, and more. Further policy caveats are outlined in the concluding section.
Quality Education for All: A Fuzzy Set Analysis of Sustainable Development Goal Compliance
Authors: Carvalho Luísa , Almeida Dora , Loures Ana , Ferreira Paulo , Rebola Fernando
Published: June 2024

The relationship between education and societal development is unquestionable. Education contributes to achieving both societies’ and individuals’ social and economic goals. Quality education is recognized as one of the Sustainable Development Goals (SDGs), which, jointly with other behaviors and attitudes, could impact the development of societies in other fields like health and well-being, cultural preservation, environmental sustainability, and even peace and stability—all of them also listed as SDGs. However, the capacity, or not, to reach higher levels of compliance with quality in education (SDG 4) varies from country to country, according to the 2023 Sustainable Development Report results. Thus, the present study aims to identify the sufficient conditions for achieving higher levels of quality education (SDG 4) globally and to analyze how these conditions vary across different world regions. Applying a fuzzy set qualitative comparative analysis and using data from the 2023 Sustainable Development Report, we focus our analysis on four SDG 4 indicators—early education, primary education, lower secondary education, and literacy rate—across 117 countries, in order to assess the conditions for attaining higher levels of quality education. The results reveal there are specific and identifiable conditions that are sufficient for achieving higher levels of quality education on a global scale, with significant regional variations. These insights contribute to understanding the complex dynamics of educational quality and could be used as guidance for policymakers and educators aiming to improve educational outcomes worldwide.
Reframing Resilience Narratives for (Rural) Communities Using the Actantial Model
Authors: Ampleman Luc , de Vries Walter Timo
Published: June 2024

As polities of all kinds are under pressure to achieve socio-environmental sustainability and resilience, existing assessment tools diagnosing communities’ vitality assets and vulnerabilities face challenges. These include grappling with incomplete data, incongruent models, and diverse indicator schemes from various scientific and professional domains. Moreover, these assessments draw upon multiple, sometimes unclear, and occasionally overlapping conceptualisations of ‘sustainability’ and ‘resilience’. This complexity makes monitoring system dynamics difficult, particularly in smaller rural communities with limited resources. This essay addresses this science policy and epistemic dilemma by proposing Greimas’s actantial model as a solution. The model, initially designed for understanding language and stories, is adapted to connect and integrate diverse data and indicator narratives across disciplines to inform policies at various levels of governance. This essay discusses recent debates on the conceptualisation of sustainability/resilience and its associated challenges, exploring how Greimas’s model may allow more constructive dialogue about conflicting views on resilience and sustainability. The model is presented as a planning template to foster communication across disciplines, social actors, and polities. The conclusion emphasises the model’s simplicity as a tool to overcome jargon, bridge communication gaps, and provide guidance for smaller rural communities facing resource constraints in assessing and implementing initiatives for sustainability and resilience.
A Study on the Willingness of “Generation Z” Consumers to Use Online Virtual Try-On Shopping Services Based on the S-O-R Framework
Authors: Wang Zhicheng , Jiang Qianling
Published: June 2024

Virtual try-on services, which significantly reduce return rates and enhance user shopping experiences, pose a crucial question: how can user willingness to use these services be increased? Additionally, “Generation Z” consumers, known for their unique traits and significant consumption potential, have been relatively understudied in this context. To address this theoretical gap, this study employs the Stimulus–Organism–Response (S-O-R) theory as its research framework, using online virtual shoe try-on services as a case study. Focusing on “Generation Z” consumers, this study utilizes literature review, user research, factor analysis, and linear regression to establish a user experience evaluation scale and behavior model. The user experience evaluation scale identifies positive elements such as convenience, price value, visual information acquisition, emotional value, and social interaction. The negative elements include technical limitations, personalized service deficiencies, and uncertainty. In the behavior model, all elements influence user attitudes. Notably, only the negative elements directly affect users’ willingness to use the service, except social interaction among the positive elements, which positively impacts usage intention. This study also reveals that “Generation Z” consumers have novel requirements for social interaction. This research effectively addresses existing theoretical gaps and provides a foundational theory for the development of related services and technologies.
Macroplastic and Microparticle Pollution in Beach Sediments from Urias Coastal Lagoon (Northwest Mexico)
Authors: Alvarado-Zambrano Daniela , Rivera-Hernández José R. , Green-Ruiz Carlos
Published: June 2024

This study investigates the occurrence and characteristics of macroplastic and polymer microparticles in the Urias coastal lagoon’s beach sediments, in northwest Mexico. Coastal lagoons, productive and vulnerable ecosystems, are impacted significantly by anthropogenic activities, leadings to their pollution by various contaminants, including plastics. Our research involved sampling sediments from four sites within the lagoon that were influenced by different human activities such as fishing, aquaculture, thermoelectric power plant operations, industrial operations, and domestic wastewater discharge. Our methodology included collecting macroplastics and beach sediment samples, followed by laboratory analyses to identify the plastic debris’ size, shape, color, and chemical composition. The results indicated a notable presence of macroplastic items (144), predominantly bags, styrofoam, and caps made of polyethylene (PE), polypropylene (PP), and polyethylene terephthalate (PET). The polymer microparticles were mainly fibers, with cotton and polyester as the most common polymers, suggesting a significant contribution from clothing-related waste. The dominant colors of the microparticles were blue and transparent. High densities were observed in areas with slower water exchange. Our findings highlight the urgent need for better waste management practices to mitigate plastic pollution in coastal lagoons, preserving their ecological and economic functions.
The GSTP1 rs1695 Polymorphism Is Associated with Mercury Levels and Neurodevelopmental Delay in Indigenous Munduruku Children from the Brazilian Amazon
Authors: Silva Mayara Calixto da , Basta Paulo Cesar , Hofer Cristina Barroso , Oliveira Mirian Akiko Furutani de , Kempton Joeseph William , Oliveira Rogério Adas Ayres de , Vasconcellos Ana Claudia Santiago de , Perini Jamila Alessandra
Published: June 2024

Genetic polymorphisms may influence mercury (Hg) toxicity. The aims of this study were to evaluate individual factors, such as the presence of the GSTP1 rs1695 polymorphism, associated with internal Hg dose and child neurodevelopment in indigenous people from the Brazilian Amazon chronically exposed to Hg. Eighty-two indigenous children were clinically evaluated, hair Hg was measured, and the GSTP1 rs1695 polymorphism was genotyped. The mean age was 4.8 years, the median Hg was 5.5 µg/g, and 93.8% of children exceeded the safe limit (2.0 µg/g). Fish consumption was associated with Hg levels (p = 0.03). The GSTP1 rs1695 A>G polymorphism was in the Hardy–Weinberg equilibrium and the highest prevalence of the GSTP1 AA genotype (80%) was found in Sawré Aboy, which had the highest Hg levels (10 µg/g) among the studied villages. The Hg levels tended to increase over the years in males and in carriers of the GSTP1 AA genotype (0.69 µg/g and 0.86 µg/g, respectively). Nine children failed the neurodevelopmental test, all of whom had Hg > 2.0 µg/g, and 88.9% carried the GSTP1 AA or AG genotypes, previously associated with the highest internal Hg doses and neurocognitive disorders. The genetic counseling of this population is important to identify the individuals at greater risk for neurodevelopmental disorders resulting from chronic Hg exposure.
A Validation of the Equivalence of the Cell-Based Potency Assay Method with a Mouse LD50 Bioassay for the Potency Testing of OnabotulinumtoxinA
Authors: Yang Yingchao , Zhang Huajie , Yuan Liyong , Wang Shuo , Ma Xiao
Published: June 2024

(1) Background: At present, the only potency assay approved in China for the in-country testing of botulinum toxin type A for injection products is the mouse bioassay (MBA). The Chinese market for neurotoxin products is rapidly expanding, but MBAs are subject to high variability due to individual variations in mice, as well as variations in injection sites, in addition to the limited number of batches tested for one MBA. Compared with the mLD50 method, the cell-based potency assay (CBPA) developed for the potency testing of onabotulinumtoxinA (BOTOX) by AbbVie not only does not use any experimental animals but also allows for significant time and cost savings. Due to the significant benefits conferred by the replacement of the mLD50 assay with CBPA in China, the CBPA method has been transferred, validated, and cross-validated to demonstrate the equivalence of the two potency methods. (2) Methods: The differentiated SiMa cells were treated with both BOTOX samples and the reference standard, and the cleaved SNAP25197 in the cell lysates was quantified using Chemi-ECL ELISA. A 4-PL model was used for the data fit and sample relative potency calculation. The method accuracy, linearity, repeatability, and intermediate precision were determined within the range of 50% to 200% of the labeled claim. A statistical equivalence of the two potency methods (CBPA and mLD50) was initially demonstrated by comparing the AbbVie CBPA data with NIFDC mLD50 data on a total of 167 commercial BOTOX lots (85 50U lots and 82 100U lots). In addition, six lots of onabotulinumtoxinA (three 50U and three 100U) were re-tested as cross-validation by these two methods for equivalence. (3) Results: The overall assay’s accuracy and intermediate precision were determined as 104% and 9.2%, and the slope, R-square, and Y-intercept for linearity were determined as 1.071, 0.998, and 0.036, respectively. The repeatability was determined as 6.9%. The range with the acceptable criteria of accuracy, linearity, and precision was demonstrated as 50% to 200% of the labeled claim. The 95% equivalence statistic test using margins [80%, 125%] indicates that CBPA and mLD50 methods are equivalent for both BOTOX strengths (i.e., 50U and 100U). The relative potency data from cross-validation were within the range of ≥80% to ≤120%. (4) Conclusions: The CBPA meets all acceptance criteria and is equivalent to mLD50. The replacement of mLD50 with CBPA is well justified in terms of ensuring safety and efficacy, as well as for animal benefits.
Recapitulation of Peste des Petits Ruminants (PPR) Prevalence in Small Ruminant Populations of Pakistan from 2004 to 2023: A Systematic Review and Meta-Analysis
Authors: Zafar Saad , Sarfraz Muhammad Shehroz , Ali Sultan , Saeed Laiba , Mahmood Muhammad Shahid , Khan Aman Ullah , Anwar Muhammad Naveed
Published: June 2024

Peste des petits ruminants (PPR) is an extremely transmissible viral disease caused by the PPR virus that impacts domestic small ruminants, namely sheep and goats. This study aimed to employ a methodical approach to evaluate the regional occurrence of PPR in small ruminants in Pakistan and the contributing factors that influence its prevalence. A thorough search was performed in various databases to identify published research articles between January 2004 and August 2023 on PPR in small ruminants in Pakistan. Articles were chosen based on specific inclusion and exclusion criteria. A total of 25 articles were selected from 1275 studies gathered from different databases. The overall pooled prevalence in Pakistan was calculated to be 51% (95% CI: 42–60), with heterogeneity I2 = 100%, τ2 = 0.0495, and p = 0. The data were summarized based on the division into five regions: Punjab, Baluchistan, KPK, Sindh, and GB and AJK. Among these, the pooled prevalence of PPR in Sindh was 61% (95% CI: 46–75), I2 = 100%, τ2 = 0.0485, and p = 0, while in KPK, it was 44% (95% CI: 26–63), I2 = 99%, τ2 = 0.0506, and p < 0.01. However, the prevalence of PPR in Baluchistan and Punjab was almost the same. Raising awareness, proper surveillance, and application of appropriate quarantine measures interprovincially and across borders must be maintained to contain the disease.
A Water Demand Forecasting Model Based on Generative Adversarial Networks and Multivariate Feature Fusion
Authors: Yang Changchun , Meng Jiayang , Liu Banteng , Wang Zhangquan , Wang Ke
Published: June 2024

Accurate long-term water demand forecasting is beneficial to the sustainable development and management of cities. However, the randomness and nonlinear nature of water demand bring great challenges to accurate long-term water demand forecasting. For accurate long-term water demand forecasting, the models currently in use demand the input of extensive datasets, leading to increased costs for data gathering and higher barriers to entry for predictive projects. This situation underscores the pressing need for an effective forecasting method that can operate with a smaller dataset, making long-term water demand predictions more feasible and economically sensible. This study proposes a framework to delineate and analyze long-term water demand patterns. A forecasting model based on generative adversarial networks and multivariate feature fusion (the water demand forecast-mixer, WDF-mixer) is designed to generate synthetic data, and a gradient constraint is introduced to overcome the problem of overfitting. A multi-feature fusion method based on temporal and channel features is then derived, where a multi-layer perceptron is used to capture temporal dependencies and non-negative matrix decomposition is applied to obtain channel dependencies. After that, an attention layer receives all those features associated with the water demand forecasting, guiding the model to focus on important features and representing correlations across them. Finally, a fully connected network is constructed to improve the modeling efficiency and output the forecasting results. This approach was applied to real-world datasets. Our experimental results on four water demand datasets show that the proposed WDF-mixer model can achieve high forecasting accuracy and robustness. In comparison to the suboptimal models, the method introduced in this study demonstrated a notable enhancement, with a 62.61% reduction in the MSE, a 46.85% decrease in the MAE, and a 69.15% improve in the R2 score. This research could support decision makers in reducing uncertainty and increasing the quality of water resource planning and management.
Symptomatic diagnoses in primary care: an observational cohort study
Authors: Lehto Mika T , Kauppila Timo , Kautiainen Hannu , Laine Merja K , Rahkonen Ossi , Pitkälä Kaisu H
Published: June 2024

Background

It can be impossible to assign a definitive diagnosis for symptoms reported or observed by primary health care patients. In these situations, symptomatic diagnoses are often used.

Aim

The aim of the present study was to examine the proportion of symptomatic diagnoses among primary health care patients. We also explored which symptomatic diagnoses were most frequently recorded, as well as their distribution by age and sex.

Design & setting

This is a register-based study carried out in the public primary health care service of the city of Vantaa, Finland.

Method

Diagnoses were entered according to the 10th revision of the International Classification of Diseases (ICD-10). The data consisted of every diagnosis entered into the electronic health record between 1 January 2016 and 31 December 2018. Both absolute numbers and relative proportions of various symptomatic diagnosis recordings (chapter ‘R’) were reported.

Results

Of all the recorded diagnoses (
n
= 503 001), the proportion of R-diagnoses was 13.5% (
n
= 67 905). Diagnoses of symptoms and signs involving the digestive system and abdomen (R10–19) (3.7% of all;
n
= 18 550), the circulatory and respiratory systems (R00–09) (3.5%;
n
= 17 426), general symptoms and signs (R50–69) (3.0%;
n
= 15 165), and the skin and subcutaneous tissue (R20–23) (2.0%;
n
= 9812) were most prevalent. Age was also a major factor determining how symptomatic diagnoses were distributed between men and women. Overall, symptomatic diagnoses were more common among women than men (14.1% and 12.4%, respectively). The major categories of symptoms and signs involving the digestive system and abdomen, the skin and the subcutaneous tissue, and general symptoms and signs, were more predominant among women, while symptoms and signs involving the circulatory and respiratory systems were more common among men.

Conclusion

A symptomatic diagnosis code was recorded in about one eighth of GP appointments, although there were significant sex differences in the prevalence within and between diagnosis groups.
Mathematical proficiency siswa pada materi persamaan garis lurus ditinjau dari resiliensi matematis
Authors: Zandy Satila Sufita , Negara Habibi Ratu Perwira
Published: June 2024

This research explains students' mathematical proficiency by considering mathematical resilience in solving problems. This research sample involved 30 grade 8 junior high school students in Pringgarata, who were chosen randomly. The research method used is descriptive qualitative. Data was collected through a mathematical resilience questionnaire with 12 statements, as well as a mathematical proficiency test consisting of 2 essay questions and an interview guide. The research results show that students with high mathematical resilience have good mathematical proficiency, and students in this category have a good understanding of concepts, where conceptual fluency in solving problems, choosing strategies, and adaptive reasoning are used appropriately. Students have a productive disposition, which can be seen in their being confident in their answers in solving each question. Meanwhile, moderate mathematical resilience has good mathematical proficiency, and students in this category have a good understanding of concepts, strategies, and adaptive reasoning. However, when students' conceptual fluency is in the medium category, failure to solve the problem results in a less productive disposition, productive disposition refers to self-confidence. However, students with low mathematical resilience have good mathematical proficiency, and students in this category have a good understanding of concepts and strategies. During adaptive reasoning and conceptual fluency, students in the low category failed to solve the problem, which resulted in a less productive disposition.
As mutações do gene phox2b e sua relação com a síndrome da hipoventilação central congênita
Authors: Gomes de Lira Soares Nayani , Yumi Gushiken Karolina , Mendes Marini e Souza Marjorie
Published: June 2024

Introdução. A síndrome da hipoventilação central congênita (SHCC), está relacionada com diferentes mutações no gene phox2b, localizado no cromossomo 4p12, caracterizada pela dificuldade ou ausência na resposta ventilatória à hipercapnia (elevação na PCO2) e à hipóxia, que principalmente durante o sono, podem causar hipoventilação alveolar grave e apneias centrais. Objetivo. Investigar as mutações do gene phox2b, e a relação do estresse oxidativo com a síndrome. Método. Pesquisa bibliográfica pelo PubMed - NCBI num período de onze anos em inglês e francês, utilizando como palavras-chaves “síndrome de hipoventilação central congênita”, “estresse oxidativo” e “phox2b”. Resultados. Com o avanço no entendimento da doença, identificaram que seus portadores podem apresentar dois tipos de mutação: mutação de expansão de repetição de polialanina (PARM) e mutação de repetição não polialanina (NPARM). Constatou-se também, que cada tipo de mutação está associado a um fenótipo, sendo a NPARM relacionada a um fenótipo mais grave, onde os pacientes podem manifestar também a doença de Hirschsprung (HSCR) ou tumor benigno no mediastino. Com relação ao estresse oxidativo, foi observado um aumento de espécies reativas de oxigênio em pacientes com a síndrome, uma vez que este mobiliza vias de sinalização pró-apoptótica intracelulares degenerando alguns neurônios envolvidos na respiração, dentre eles, os que expressam phox2b. Conclusão. Esta revisão analisa as mutações do gene phox2b na SHCC e a relação do aumento de espécies reativas de oxigênio para o desenvolvimento da doença.
The power of digitalization in education: improving learning with interactive multimedia content
Authors: Bilynska Khrystyna , Markova Оlena , Chornobryva Natalia , Kuznietsov Yevhen , Mingli Wu
Published: June 2024

The article highlights the advantages of creating multimedia content in education based on digitization. Programs for creating multimedia content in education on the basis of digitalization of multimedia were analyzed and the stages of working with them were considered, which were grouped by main categories. The most important characteristics of interactive multimedia are revealed. The importance of media competence and media literacy of the teacher and student has been proven. The necessity of creating multimedia content of a cloud-oriented educational environment in our time is shown. To achieve the goal of the research, an experiment was conducted, the purpose of which is to identify more effective multimedia technologies for providing multimedia content on the basis of digitization in the field of education, where an experimental approach is the most appropriate. As a result of an experimental study of the influence of multimedia content on the quality of assimilation of educational content by students of different age categories based on digitalization, the combination of multimedia tools in various combinations made it possible to reveal the characteristic features of the multimedia phenomenon in the modern world.
Modelo sistémico de kanban del área de acabados en la industria metal-mecánica
Authors: Dorantes-Benavidez Felipe de Jesus , Martínez-Cruz Miguel Ángel , Dorantes-Benavidez Humberto , Chávez-Pichardo Mauricio , Acosta-Mendizabal Marco Antonio
Published: June 2024

El trabajo de investigación tiene la finalidad de modelar un sistema que controle el flujo de materiales utilizando la herramienta de mejora continua (Kanban), al mismo tiempo sirva como un indicador de calidad que especifica la calidad de las piezas procesadas del área de acabados en la industria de Metal- Mecánica TEXNOTEJ S.A de C.V., evitando acumulación de inventarios temporales de producción, permitiendo agilizar las tareas adecuadas y mejorando la gestión eficiente del trabajo. Los datos obtenidos pertenecen a la empresa TEXNOTEJ S.A de C.V. en el que se consideran 12 trabajadores por turno, el departamento a mejorar es el área de terminado a través de un Diseño de una red de modelado sistémico basada en (Kanban) la cual se programa con el software Arena 6ta Edición, que permite asignar adecuadamente la multitarea, así como incrementar las capacidades eliminando los cuellos de botella.
Impact of illegal orders on the Ukrainian banking system: a constitutional analysis
Authors: Naturkach Ruslan , Lankevych Andriy , Bysaha Yurii Y. , Bysaha Yurii M. , Prodan Viktoriia
Published: June 2024

This article examines illegal orders and orders in the field of the banking system from the point of view of constitutional law. The study includes a review of constitutional norms and principles related to banking, analysis of specific cases of issuance of illegal orders, as well as study of mechanisms for protecting the rights of subjects of banking relations. The purpose of the article is to analyze illegal orders and orders in the banking system in the context of constitutional rights and freedoms. The methodology of the article includes such methods as: analysis method, historical-legal method, comparative method, logical method. As a result of the study, it was concluded that the Constitution of Ukraine enshrines basic rights and freedoms that directly affect the functioning of the banking system. In particular, this is the right to property, entrepreneurial activity, and the right to legal protection. The study showed that these constitutional guarantees are key to protecting the rights of subjects of banking relations from illegal orders and orders. The results of the study emphasize the need to improve the legal regulation of banking activity in Ukraine, in particular by eliminating existing shortcomings in the legislative framework and strengthening the mechanisms for protecting the rights of subjects of banking relations. The implementation of the proposed recommendations will contribute to ensuring legality and law and order in the banking sector and increasing trust in the banking system of Ukraine.
The legacy of Nizami Ganjavi in Transoxiana: An analysis of Khamsa's influence on oral narrative
Authors: Shoaliyeva Nargiza
Published: June 2024

Nizami Ganjavi, one of the distinguished poets of the 12th century, has a special place in world literature with his works from ancient times to the present. This poet is famous not only in Persian literature but also in Turkish and Indian literature. Nizami Ganjavi is related to the Mesnevi works, which were translated into Turkish and even translated by many Turkish poets and writers in the following centuries. Among these, we can count the essential figures of Chagatai Turkish literature (Transoxiana), especially Emir Alişer Nevai, who cared about Mesnevi Khamsa Nizami and made changes and wrote examples based on his stories. Nizâmî, with the dreams and images created in the Mesnevi above, has revealed an original style that is very important in today's comparative literature field at the international level. He proved his success by creating a new style of fantasy drawing using imaginary images, and many poets influenced by him entered the field of literature. This article refers to Panj Ganj or Khamsa Nizami Ganjavi's works and tries to explore his influence on Transoxiana writers. The study uses a qualitative, library, and comparative methodology and is founded on the laws and categories of scientific research. Researchers applied modern research approaches and methods (general scientific analysis, comparison, generalization, systematization, text analysis, and retrospective analysis).
Operative and search counteraction to crimes committed in the sphere of activity of institutional investors in Ukraine
Authors: Vazhynskyi Volodymyr , Pohoretskyi Mykola , Toporetska Zoriana , Cherniak Andrii , Serhieieva Diana
Published: June 2024

The purpose of this study is to analyze the methods, means and possibilities of operative and search counteraction to crimes committed in the sphere of activity of institutional investors. To achieve this goal, it is necessary to solve the following tasks: analyze the dynamics of crime in the sphere of activity of institutional investors; to characterize the concept and structure of operative and investigative countermeasures against crimes; determine the content of operative and investigative prevention, detection, and documentation of crimes in the field of activity of institutional investors. As a result of the research, it was possible to establish that in the structure of operational and investigative countermeasures against crimes in the field of activity of institutional investors, we distinguish prevention, detection, and documentation of criminal offenses.
Towards an Environmental Justice: Linda Hogan’s Ecoresistance
Authors: Althobaity Najmah
Published: June 2024

Linda Hogan is a Chickasaw poet who wrote various volumes of poetry that reflect her love for Chickasaw’s history, land, and oral traditions. She also wrote about the environment and the natural world. Although she is a well-known environmentalist, scholars have not investigated her environmental vision and its connection to native traditions and the ecosystem, specifically in her collection of poetry Dark. Sweet: New & Selected Poems (2014).
This study aims to answer the following questions: What is the environmental perspective of Linda Hogan in her collection of poetry Dark. Sweet: New & Selected Poems (2014)?  How does she present environmental justice in her poetry? How does she connect her environmental vision to her tribal heritage? The study also deals with Hogan’s holistic representation of the human experience in the natural world. Through the application of the ecocritical approach, the study reveals the poet’s depiction of past injustices of colonization and its lingering ecological effects on humans and the ecosystem. Additionally, it examines Native American storytelling and traditional healing practices and how they can form the balance between human, ecological and spiritual system.
The study adopted a qualitative method that involves a thematic analysis of the poet’s work. The findings show that Hogan communicates her tribal ecological vision through her strategy of ecoresistance. They also reveal that humans and the ecosystem were the discounted casualties of European colonization. For Native Americans, to decolonize themselves and the land, they must strive for environmental justice along with seeking the right for self-determination. The researcher recommends conducting a study that identifies the influence of Hogan’s Anglo culture on her environmental poetic writings by considering that she is of mixed-blood heritage.
العوامل المؤثرة في تشكيل القرار السياسي في العصر الأموي: ولاة العهد والأمراء الأمويين أنموذجاً (41- 64هـ/ 661- 684م) دراسة تاريخية
Authors: باحشوان خلود
Published: June 2024

سعت هذه الدراسة إلى الكشف عن دور بعض القوى في تشكيل القرار السياسي في الفترة السفيانية من العصر الأموي، وركزت على بيان دور إحدى الفئات (ولاة العهد والأمراء الأمويين) باعتبارها ذات الأثر الأكبر في صنع القرار السياسي في العصر الأموي كونها الأقرب من الخليفة والملازمة له بحكم القرابة والأحقية.
اعتمدت الباحثة في هذه الدراسة على المنهج التاريخي الوصفي والمنهج التحليلي القائم على جمع الروايات التاريخية وتحليلها من أجل التوصل إلى نتائج الدراسة.
خَلُصت الدراسة إلى عدد من النتائج كان أبرزها: أن سلطة الخليفة الأموي في اتخاذ القرارات كانت محكومة نسبيًا بعدة عوامل وقوى مؤثرة؛ أي أنها لم تكن مطلقة إطلاقًا تامًّا كما يبدو لكثير من الناس، إضافةً إلى تفاوت نسبِ تأثير تلك القوى في صنع القرار السياسي الأموي تِبْعًا للظروف والأحداث ومستجدات التطورات السياسية، مع وجود الكثير من التداخل والتشابك في تأثير كل من ولاة العهد والأمراء وذلك على اعتبار أن كل ولاة العهد هم بالأساس أمراء أمويين.
توصي الباحثة بإجراء المزيد من الدراسات المقارنة للبحث عن العوامل والمؤثرات في صنع القرار السياسي في العصر الأموي، بالمقارنة مع محركات صنع القرار في العصر العباسي، والتبحر في البحث عن دور الأمراء وولاة العهد العباسيين ومقارنتهم بنظرائهم الأمويين في علاقتهم بقصر الخلافة.
ظاهرة المتضامات المتضادة وتجلياتها في لغة الحكمة بديوان الإمام الشافعي- دراسة المستويات اللغوية الصغرى
Authors: الديحاني أمينة
Published: June 2024

هذه مقاربة لسانية لمجموعة من المقولات الشعرية في ديوان الإمام الشافعي، تُجَلّي ظاهرة لغوية يكاد يتفرد بها، وهي الائتلاف بين جوانب الاختلاف، وقد اصطلحت الدراسة على تسميتها بالمتضامات المتضادة، وتطرح الدراسة تساؤلات افتراضية؛ منها: ما خصائص النهج اللغوي للتعبير عن تلك الظاهرة؟ وما دورها في إحداث السبك النصي؟ وكيف أبرزت تجلياتها غرض الحكمة؟ وقد شرعت الدراسة بعرض مفهوم الحكمة، والتعريف بالمتضامات المتضادة، وبيان وسائطها اللغوية، ورصد أوعيتها النسقية وأنماطها المختلفة، وإظهار تجلياتها على لغة الحكمة في المستويات اللغوية الصغرى، وقد سلكت الدراسة المنهج الاستقرائي التحليلي وصولاً للنتائج؛ ومنها الخروج بتصنيف المتضامات المتضادة في أنساق تعبيرية؛ نحو الجمع بين النقيضين في الشيء الواحد والمتعدد، ومناقضة الشيء لنفسه، وغير ذلك، كما وقفت الدراسة على أنماط التعبير بالضدية؛ ومنها ما تندرج في حكم التضاد الموجب أو السالب أو البائن أو المركب أو المجازي، وبيان تجلياتها الصوتية بما تحمله من ملامح تمييزية؛ وإظهار سيميائية الأصوات والمصطلحات الصوتية فوق الثانوية، والتماس إيقاعها الصوتي. وأما تجلياتها الصرفية فبدت بقولبتها في أوزان صرفية خاصة، تدل على معاني الثبات والتغير في تلازم المتضادات أو تنافرها، وإحداثها التوازن الصرفي باستخدام المحسنات البديعية. وأما التجليات المعجمية فتظهر في العقد المفاهيمي بين المتنافرات بنطاق تقابلي، وإيجاد المناسبة بين الدوال والمدلولات وفقًا للحقول المعجمية، وتفصيل المجمل وتخصيص العام، والتقسيم اللفظي في السرد التضامي، وإحداث التجانس المعنوي والجناس اللفظي.
وبينت الدراسة كيف تجاوز الشافعي حدود هذه الظاهرة الأسلوبية بتصورها التجريدي ونظاميتها إلى استقراء جمالياتها؛ وذلك باستغلال الناتج الدلالي، وصناعة الفارق الأسلوبي، وسبك النص ببنيتيه السطحية والعميقة، والوصول إلى سببية انتخاب تلك البُنى في مسائل التعدد والاختيار، وإقامة الحجة العقلية عليها. وهذه الدراسة في أصالتها تدعم الحركة البحثية، وتدعو إلى إبداء ما يكتنف الإرث الشعري من ظواهر، وتحليلها على جميع المستويات اللغوية، وهذا مسلك منهجي قد يكون مغيّبًا في الدرس اللساني الحديث، كما أن المعالجة البحثية تحتاج إلى سبر أغوار تلك الظواهر؛ للوقوف على ماهيتها، واستدراك عوالقها، وبيان قيمتها اللغوية والفنية في تحقق بناء النص، واكتمال أركانه.
دراسة وصفية تحليلية مقارنة لطاسة خضة محفوظة بمتحف جورجيا الوطني "تنشر لأول مرة"
Authors: عبيد شبل
Published: June 2024

تعد طاسات الخضة من بين التحف المعدنية الهامة؛ لما تتضمنه من نقوش كتابية وأدعية وطلاسم سحرية، تعكس الأوضاع الاجتماعية والمعتقدات المتوارثة لدى الشعوب الإسلامية، بالإضافة إلى العناصر الزخرفية المتنوعة.
ويهتم البحث بدراسة طاسة خضة محفوظة بالمتحف الوطني (سيمون جاناشيا) بمدينة تفليس، تحمل رقم سجل 3690، وما عليها من زخارف متنوعة.
تهدف الدراسة إلى وصف هذه الطاسة وصفاً فنياً مع تحليل لأهم العناصر الزخرفية، والنقوش الكتابية، ومدى ارتباطها بوظيفة الطاسة، إلى جانب رسوم الأبراج الفلكية والطلاسم السحرية، وتكمن إشكالية الدراسة في أن الطاسة غير مؤرخة؛ ومن ثم سوف نؤرخها من خلال مقارنتها بطاسات أخرى مؤرخة أو منفذ عليها العناصر الزخرفية نفسها، وذلك من خلال المنهج الوصفي والتحليلي المقارن.
ومن بين النتائج التي توصلت إليها الدراسة:

اتسمت الطاسة موضوع الدراسة بتنوع مضامين النقوش الكتابية المنفذة عليها ما بين النقوش الدينية والمذهبية والأدعية؛ ومن بينها دعاء " القدح " الذي ورد على العديد من طاسات الخضة وتراكيب القبور وغيرها.
أكدت الدراسة على أن الطاسة قد آلت ملكيتها إلى عدة أشخاص خلال فترات زمنية متعاقبة، ويوضح ذلك كشط اسم صاحب الطاسة المدون على القاعدة باللغة الفارسية.
أثبتت الدراسة أن من بين الأسماء التي أطلقت على طاسات الخضة في العهد الصفوي اسم "طاسة الدعاء" وهذا الاسم لم يطلق على طاسات الخضة من قبل.
رجحت الدراسة بناءً على المقارنات مع الطاسات الأخرى التى تتضمن العناصر الزخرفية نفسها والأبراج الفلكية نسبة هذه الطاسة إلى إيران في العهد الصفوي قرب نهاية النصف الأول من القرن الحادي عشر الهجري / ق17 م.

تحتاج هذه التحفة إلى إعادة ترميم وصيانة؛ نظراً لقيمتها الفنية والأثرية العالية.