bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Prefabricated Materials in Architecture During the Pandemic and Post-Pandemic
Authors:   Departemen Teknik Arsitektur, Universitas Komputer Indonesia, Indonesia, Ramadhianto Mochamad Faisal , Risman Dede ,   Departemen Teknik Arsitektur, Universitas Komputer Indonesia, Indonesia, Bimantoro Dhimas ,   Departemen Teknik Arsitektur, Universitas Komputer Indonesia, Indonesia, Hirawan Dedeng ,   Departemen Teknik Informatika, Universitas Komputer Indonesia, Indonesia, Jumansyah Rizky ,   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia
Published: March 2022

The purpose of this study is to determine and analyze how big the role of prefabricated materials in increasing construction efficiency in architecture, especially in the post-pandemic era. This research was conducted using qualitative methods because it relates to the views of researchers regarding to the relationship between prefabricated materials and post-pandemic phenomenon. The results obtained from this research are the application of prefabricated material technology that can help the construction process in architecture to be faster in several aspects. The presence of prefabricated materials in architecture, especially post-pandemic, can make the construction process faster in terms of time and installation. The presence of prefabricated materials in architecture, especially post-pandemic, can make the construction process faster in terms of time and installation. Therefore, the use of prefabricated materials is very well applied both during the pandemic and post-pandemic because it can break down the processing time faster so as to minimize the crowd of workers in the field. The final result of this research is to find out how big the role of prefabricated materials in architecture is to make work in the field more efficient and minimize crowds during the pandemic or post-pandemic period. We hope that this research can be useful for the architectural world regarding the advantages of applying prefabricated materials during the pandemic and post-pandemic era.
A Calamity of Errors: THE UNTOLD STORY OF THE 5TH REGIMENT AT BLANC MONT RIDGE ON 4 OCTOBER 1918
Authors: Gregory Jr. James P.
Published: March 2022

The Battle of Blanc Mont on 4 October 1918 had the worst single day’s casualties for the Marine Corps in World War I with the 5th Regiment suffering 1,097 casualties. However, the details of the attacks by the 5th Regiment are very commonly left out or glossed over in official accounts, memoirs, and discussions after the war. Why is this important and why is an analysis of the actions on this horrific day absent from so many primary sources? The answer is multifaceted: command’s failure to properly coordinate the attack, senior leaders lacking awareness due to posts of command initially remote from the front lines, overzealous Marines, a chaotic retreat, and a lack of acknowledgment of 4 October after the war. The untold story of 4 October, the good and the bad, deserves to be recognized in order to remember those Marines who gave their lives that day and to acknowledge the lessons from the failures, blunders, and defeat, as they are also a part of the larger history of actions of the Marine Corps in World War I.
Strategic Communication through Narration: HOW U.S. MARINE CORPS COMMANDANTS STILL USE STORY TO INSPIRE SUPPORT
Authors: Ball Meriwether , Brown William J.
Published: March 2022

During the past four decades Walter R. Fisher’s narrative theory has been developed and applied to many different areas of communication study. Yet, to date, extraordinarily little research has applied Fisher’s theory to the study of military communication, despite Fisher’s own formative experiences as a Marine, combat veteran in Korea, and drill instructor. This study illustrates how Fisher’s theoretical framework provides a useful model for studying how Marine Corps Commandants strategically use storytelling to communicate important messages to those within their community. By examining three artifacts as communicative narratives, we explore how Commandants have used Fisher’s tools to persuade their fighting forces to grasp their perspective about the situated circumstances, posture, and future direction of their command. Implications of storytelling as a powerful communication tool in the military and recommendations for future research are discussed.
DECAY RESISTANCE AND CHANGES IN CHEMICAL COMPOSITION OF TWO FAST-GROWING TREE SPECIES NEOLAMARKCIA CADAMBA AND OCHROMA PYRAMIDALE
Authors:   School of Agriculture, Utsunomiya University, Japan, PERTIWI YUS ANDHINI BHEKTI , ISHIGURI FUTOSHI ,   School of Agriculture, Utsunomiya University, Japan, AISO HARUNA ,   School of Agriculture, Utsunomiya University, Japan, IRAWATI DENNY ,   Faculty of Forestry, Gadjah Mada University, Indonesia, OHSHIMA JYUNICHI ,   School of Agriculture, Utsunomiya University, Japan, HABU NAOTO ,   School of Agriculture, Utsunomiya University, Japan, YOKOTA SHINSO ,   School of Agriculture, Utsunomiya University, Japan
Published: March 2022

"In the present study, the decay resistance and the changes in the amounts of chemical components of wood as a consequence of decay by Fomitopsis palustris and Trametes versicolor were investigated for two tropical fast-growing tree species – Neolamarckia cadamba and Ochroma pyramidale. Decay tests were conducted according to Japanese Industrial Standards K1571: 2010. The amounts of the extractives, holocellulose and lignin were determined for wood specimens after 30, 60 and 90 days of incubation. Neolamarckia cadamba wood underwent higher mass loss when decayed by F. palustris, compared to T. versicolor, while O. pyramidale showed the opposite results. All of the main chemical components of the wood started to degrade on the 30th day of incubation, indicating that N. cadamba and O. pyramidale wood is vulnerable to attacks by both types of fungi. In addition, during the decay period, the patterns of degradation that the chemical components of wood exhibited differed from one species to another."
DEVELOPMENT OF MULTICOMPONENT FIBER BOX WITH IMPROVED FIRE RESISTANCE AND BARRIER PROPERTIES
Authors:   Pulp and Paper Institute, Ljubljana, Slovenia, JUHANT GRKMAN JANJA , KAVCIC URŠKA ,   Pulp and Paper Institute, Ljubljana, Slovenia, KARLOVITS IGOR ,   Pulp and Paper Institute, Ljubljana, Slovenia
Published: March 2022

"One of the main purposes of packaging materials is to protect the packed object from mechanical damage that can happen during transport, storage or handling. Extending the functionality of packaging from just mechanical protection to additional moisture and fire protection would present an added value to packaging materials and would be of high interest in preserving archives and cultural heritage objects. In the present research work, we developed a pH neutral fibre material that provides a moisture barrier, inhibits burning and can be shaped into different packaging designs. A multilayer composite was developed, with the outer layers made from pH neutral acid-free paper, compatible with ISO 9706:2014 (the requirement for permanence) and ISO 11108:2016 (the requirement for permanence and durability). The produced pH neutral papers were coated (on the inside) with 6 different combinations of moisture barrier agents and fire-retardant coatings (containing styrene acrylic copolymer, hydrostatin, sodium silicate + aluminium hydroxide/carbonate and lignin), combined into a multilayer material. The developed materials were analysed in terms of their water vapour transmission rate, Cobb absorption and fire retardancy to simulate worst-case scenarios for archives or cultural heritage sites. The results showed that the material coated with the combination of styrene acrylic copolymer aqueous dispersion and mixtures of sodium silicate and aluminium hydroxide achieved the best performance in terms of moisture/fire resistance and could be successfully converted into packaging products for protecting museum objects. "
Zazakî de Romano Yewin: Dêrsim’ra ve Dare Estene Seyit Rıza
Authors: ANUK Nevzat , AYDOĞDU Yusuf
Published: March 2022

Na xebate, sebebanê ereymendişê romanê Zazakî sero munaqaşa kena û nê sebaban dana verê çiman. Hetê ereymendişê romanê Zazakî de sebebanê polîtîk sero yew panaromaya kronolojîk dana. Wertevêjîyayişê romanê Zazakî de rolê dîyasporayî sero vindena. Mîyanê xebatanê edebî yê Zazakî de hetê tarixê edebîyatê Zazakî de hetanî ewro romano tewr verên sey Klama Pepûgî yeno qebul kerdene. Armancê na xebate no yo ke; tarixê edebîyatê Zazakî de zanayişê romano yewinî sero de yew îddîaya newe do bierzo werte. Îddîayê na xebate na ya ke; Klama Pepûgî ra ver, eserê Dêrsim’ra ve Dare Estene Seyit Rıza ke çap bîyo. Na xebate de eserê Dêrsim’ra ve Dare Estene Seyit Rızayî bi metodanê analîzê romanî do bêro analîzkerdene.
Experimental Impact on Mechanical Characteristics of Banana Fiber Reinforced, Groundnut Shell Powder Filled Epoxy Resin Matrix Bio Composites
Authors:   Assistant Professor, Department of Mechanical Engineering, Nandha College of Technology, Erode, Tamilnadu, India., Girimurugan* R. , Vairavel M. ,   Assistant professor, Department of Mechanical Engineering, Anna Poorna Engineering College,Salem, Tamilnadu, India., Shanjai S. Dharun ,   UG Student, Department of Mechanical Engineering, Nandha College of Technology, Erode, Tamilnadu, India., Manikandan S. ,   UG Student, Department of Mechanical Engineering, Nandha College of Technology, Erode, Tamilnadu, India., Manikkumar R. ,   UG Student, Department of Mechanical Engineering, Nandha College of Technology, Erode, Tamilnadu, India., Manojkumar R. ,   UG Student, Department of Mechanical Engineering, Nandha College of Technology, Erode, Tamilnadu, India.
Published: March 2022

The outcome of adding together naturally available reinforcement material to the natural fiber epoxy composite was examined experimentally. Composites mates were manufactured with the help of a conventional hand-layup method. All composites are prepared with constant weight fraction (30%) of banana fiber with dissimilar weight fraction of (0, 2, 4, 6%) groundnut shell powder is added to the epoxy composite. As per the ASTM standards, test specimens were cut away from the composite mate using the water jet machining process. Tension, compression, hardness, impact, flexural and water absorption tests were conducted according to ASTM standards, to discover the mechanical behavior of the composites. Experimental results represent that mechanical properties are considerably enhanced by means of the adding up of groundnut shell powder to the epoxy-based banana fiber composite.
Artificial Intelligence, Analytics and Agile: Transforming Project Management in the 21st Century
Authors:   Project Management Consultant, Forbes Business Council Member, Board Member @ PMI South Florida, Florida, US., Gupta Shivani
Published: March 2022

With the advent of intricate and advanced technologies, methods, and automation, several challenges have emerged that need to be addressed. Artificial Intelligent Technology, Agile and Analytics holistically improve the project management discipline through continuous improvement and consistent execution. This paper builds upon this discussion and establishes how project management is using the AI supported tools, extensive use of data analytics and the Agile approach for improvement. Technology is revolutionizing the project management, yet the role of project managers cannot be undermined since they are the primary drivers of the project and deliver value.
APPLICATION OF TRANSLATION SKILLS WHILE TRANSLATING THE NOVEL “KHAYOT NAVOSI”
Authors: Zaripova Ra'no
Published: March 2022

The article deals with the Uzbek translation of the novel “Tronca” (1963) (“Khayot Navosi”), written by Ukrainian writer Oles Gonchar. The researcher also comments on the specifics of the fiction prose translation on the example of this particular novel translation.
Oles Gonchar is one of the great and famous writers of Ukrainian literature. His novel “Tronca” (“Khayot Navosi”) is considered to be one of the most beautiful works of his time. This work was translated into Uzbek by Lola Tajieva. The work is written with enthusiasm and passion for the Motherland and humanity. The author expresses his love for his country and his people, presenting his beautiful and noble soul feelings in the tones harmonious to his short stories. The translation also masterfully conveys the feelings of love for the motherland, passionate feelings highlighting the harmony of a form and content, that is, the original style has not been lost in the course of translation.
The author analyzes the difficulties of translating not only the text of the novel, but also proverbs and sayings, sentences related to national values, figurative images, adjectives and analogues, translating of retrospection and re-expressing some actions and images. O.Gonchar depicts positive images in harmony with their external beauty and spiritual world, and the translator has kept this style of the author. The article is dedicated to this.
The researcher notes that the story of the Uzbek writer Asad Mukhtor “Chinor” was written in this literary and artistic style, and his glorious love for the people, especially working people is expressed with high pathos. The comparative analysis of the two translations emphasize that these two works may serve as a bridge between peoples.
THE ROLE AND METHODOLOGY OF PROJECT-BASED LEARNING IN TEACHING THE ENGLISH LANGUAGE
Authors: Karimova Nilufar
Published: March 2022

The article deals with the theoretical basis and methodological aspects of implementing Project- Based Learning in foreign language teaching. Although the roots of Project-Based Learning ideas go back to the beginning of the 19th century, the growth of researches in this area has reached its peak with the advent of the 21st century. Project- Based Learning is a systematic process that enables students to achieve learning objectives that are focused on the content of education through working on a specific project that covers real-life problems and challenges. It is impossible to ignore the fact that projects form the basis of today’s modern work environment. At the same time, the integration of Project-Based Learning in the educational process at all stages of education, especially in higher education, means the training of future professionals for real work through experience. Project-Based Learning has a special significance in foreign languages education. The use of Project-Based Learning in foreign languages teaching, including English, reflects the basic principles of communicative, learner-centered and competency-based approaches that reflect the idea of teaching a foreign language for practical purposes and are considered a priority in foreign languages teaching today. On the basis of the analysis of scientific literature and researches, the author discusses the concept of the project, the content of the project-based teaching approach and its specific features in education. The advantages of the approach, which have been proven as a result of the research, are described, and types of projects are presented by typological classification. The main goals of implementing Project-Based Learning in the English language teaching are analyzed. The main stages of Project- Based Learning, the important elements are explained on the basis of the studied literature in the field. Besides, the author presents the typology of difficulties in macro and micro systems that can be encountered in applying Project-Based Learning in foreign languages teaching.
THE ROLE OF COMPETENT APPROACH TO TEACHING FOREIGN LANGUAGES TO JOURNALISM STUDENTS
Authors: Khazratova Zukhra
Published: March 2022

The introductory part of the article presents historical facts about the field of journalism and how and when its primary education was formed. Also, the scientific significance of the research results in the field of journalism is explained by the usefulness of the proposed system, methodology, evaluation criteria to improve the content and methodological basis of journalism in higher education, and researches on teaching journalism terms.
Practical significance of the research results, the developed proposals and practical recommendations provide theoretical insights on the formation and development of lexical competence in media terms, improvement of curricula in students majoring in journalism in higher education in English. The main part of the article is devoted to the importance of a competent approach to teaching foreign languages to journalism students.Theoretical and practical analysis of the importance of having language skills, mainly communicative competencies, for journalism students not only in language learning but also in the formation of professional skills is analyzed in the article. It mainly studies the importance of training and project methods in training journalists for the profession. The theoretical aspect of the article is mainly based on the competency approach and these two methods with the opinions of the researchers.
In the practical part of the article, based on the theory, an experiment was conducted with students of the Faculty of Journalism. As a result of the project method, students' language skills increased and they worked on other specialties. In short, there are different approaches to learning English, and one of them is the communicative approach. This method helps to overcome language practice fear and language barriers in teaching English. The use of a competency-based approach in teaching foreign languages to journalist students during the lesson is an important factor in improving students' professional and language skills in their fields.
TYPOLOGY AND STRUCTURAL FEATURES OF RADIO SHOWS
Authors: Ismailova Klimentina
Published: March 2022

The article considers a Show as a widespread form of radio broadcasting and investigates its structure and main typological features. The specificity of radio shows is revealed through the prism of comparative analysis with television talk shows, determined with peculiarity of their perception by recipients. The factors that prove the popularity of a very broadcasting phenomenon are identified. A classification of radio shows is given according to the ratio of program elements, the time criterion, the composition of the presenters, etc. Weekend radio shows and specialized shows are also characterized. The key components of a Show and its stylistic features are analyzed in the structure of the air of radio stations. The necessity of a balanced ratio of music, information, advertising, rubrics under a radio show, is also presented.
The author substantiates the position that a well-built show contributes to the identification of a radio station in a polyphonic broadcast, and the compliance of the concept of the channel ensures its successful positioning in the media environment, expanding the contingent of listeners.
Using the example of the practice of radio stations in Uzbekistan, the role of an interactive component of a radio show is shown; ways of attracting an audience to game types of broadcasts, to express opinions on topical issues, to co-authorship are presented. The analysis of media planning of advertising and sponsored videos has been carried out.
Particular attention is paid to the study of dialogical interaction under radio shows: between presenters, between presenters and guests of the program, between presenters and listeners.
On the hypercomplex numbers of all finite dimensions: Beyond quaternions and octonians
Authors: Singh Pushpendra , Gupta Anubha , Joshi Shiv Dutt
Published: March 2022

In search of a real three-dimensional, normed, associative, division algebra, Hamilton discovered quaternions that form a non-commutative division algebra of quadruples. Later works showed that there are only four real division algebras with 1, 2, 4, or 8 dimensions. This work overcomes this limitation and introduces generalized hypercomplex numbers of all dimensions that are extensions of the traditional complex numbers. The space of these numbers forms non-distributive normed division algebra that is extendable to all finite dimensions. To obtain these extensions, we defined a unified multiplication, designated as scaling and rotative multiplication, fully compatible with the existing multiplication. Therefore, these numbers and the corresponding algebras reduce to distributive normed algebras for dimensions 1 and 2. Thus, this work presents a generalization of $\mathbb{C}$ in higher dimensions along with interesting insights into the geometry of the vectors in the corresponding spaces.
L-Arginine’s Glucose Homeostatic Influence in Renal Damaged Wistar Rats is Possibly Mediated by Adiponectin Expression
Authors: Ajiboye Kolawole I. , Alabi Great O. , Ajiboye Oyebimpe F. , Erechukwu Chinaza E.
Published: March 2022

Hypoglycemia, as a direct result of the glucosuria is usually seen in patients with acute kidney injury hence glucose homeostasis is disturbed. The compensatory effect of adiponectin in the insulin deficient state is documented. We previously demonstrated that L-arginine enhances glucose transport mechanisms in renal-damaged rats. The current study was designed to investigate possible glucose handling synergy between L-arginine and adiponectin in Wistar rats induced with acute kidney injury. Twenty four rats weighing between 120g-150g were divided into 4 groups of six rats each. Group 1 (Control) had normal feed and water; Group 2 (Untreated) was induced with AKI and left untreated. Group 3 and 4 took 50mg/kg and 500mg/kg L-arginine respectively after AKI induction. Acute kidney injury was induced by intra-muscular injection of glycerol (50% solution, 8 ml/kg BW). Oral glucose tolerance test, insulin response test, serum creatinine test and adiponectin assay (ELISA) were carried out. Data was analysed using one way ANOVA and expressed as mean± standard error of mean (SEM) with p ≤ 0.05 considered as significant. L-arginine induced rapid insulin-like action which was effective after thirty minutes of oral glucose loading when compared the control group. Glucose uptake from the blood was also more effective and quicker in the L-arginine treated groups. Adiponectin was significantly expressed across the test groups when compared to the control group and there was insulin resistance in the untreated kidney injured rats 1 hour into the insulin response test. It may be concluded that L-arginine has a homeostatic influence on glucose handling in kidney-damaged rats possibly mediated by increased adiponectin expression.
A Study of Female Anti-Stereotype Discourse from the Perspective of Gender Construction — Take Mrs Thatcher’s Speeches as an Example
Authors: Dong Tian , Cheng Jiaqi
Published: March 2022

In order to reveal how female figures with power construct their social identity through discourse, this paper analyzes the discourse pattern of female anti-stereotype in Mrs. Thatcher’s two speeches through data statistics from the theoretical perspective of gender construction. It is concluded that the anti-stereotype discourse pattern still reflects the social construction with male discourse as the power center, and the phenomenon of gender discrimination still exists.
Evaluation of the Antibacterial Activity and Cytotoxicity of Extracts of Endophytic Bacteria Isolated from Solanum torvum Sw (Solanaceae)
Authors: Christian NGOULE Charles , Pierre NGENE Jean , Flora LADOH-YEMEDA Christelle , Jacques YINYANG , Catherine KIDIK POUKA , Laurelle HEUDEU NGOFANKI Estelle , Nicaise AZO’O Jeanne , Gisèle ETAME-LOE
Published: March 2022

The study aimed at evaluating the antibacterial and cytotoxic potential of endophytic bacteria extracts isolated from Solanum torvum Sw (Solanaceae), a plant traditionally used in the treatment of many pathologies such as diarrheal diseases. Isolation of endophytic bacteria was done on supplemented and non-supplemented nutrient media. The extracts of these endophytes were obtained after fermentation in Muller Hinton Broth (MHB). An antibacterial screening of the extracts was carried out on 04 bacterial strains (Staphylococcus aureus, Shigella flexneri, Escherichia coli and Salmonella typhimurium). The strains having demonstrated activity were retained for the determination of the minimum inhibitory concentrations (MIC). The cytotoxicity tests of the extracts were carried out on healthy macrophage cells (Raw 264.7) and healthy kidney cells (Vero). A total of 41 isolates of endophytic bacteria were isolated from S. torvum. The antibacterial screening made it possible to retain 08 extracts which demonstrated antibacterial activity on the S. aureus and S. flexneri strains with MICs ranging from 100 to 200 μg/ml. All extracts exhibited weak cytotoxic activity except for one extract. Extracts of endophytic bacteria isolated from S. torvum showed antibacterial activity and low cytotoxicity on the pathogenic strains tested. This study shows that the endophytic bacteria of S. torvum are a source of antibacterial compounds to be explored to enrich the therapeutic arsenal against bacterial infections.
A Clinicopathological Study of Emergency Appendectomies to Evaluate Negative Appendectomy Rate in a Tertiary Care Hospital
Authors: Aithmia Dr. Rashmi , Choudhary Shagufta , Mahajan Saloni
Published: March 2022

Background: Acute appendicitis is the most common cause of acute surgical abdomen worldwide. This clinicopathological study aims to determine the negative appendectomy rates of the surgically removed appendix in our centre and to determine the diagnostic accuracy of acute appendicitis by considering HPE as the gold standard. Method: A retrospective study was undertaken to review the histopathology reports of all the emergency appendicectomy specimens submitted to the Department of Pathology Government medical college and Hospital, Jammu; from 30th June 2020 to 1st July 2021. Patient’s biodata, clinical signs and symptoms were extracted from the request forms. Result: A total of 250 appendices were received during the 1-year study period. The male to female ratio was 3.1:1 with age ranging from 5 to 75 years of age. Acute appendicitis was found in 50.4%, followed by suppurative appendicitis (20%), perforated appendix (15.2), gangrenous appendix (6.4%), acute on chronic appendicitis (8%) and 2 cases of carcinoid tumor (0.8%). NAR was calculated as 4.8%. The diagnostic sensitivity was calculated to be 95.2%. Conclusion: HPE is the gold standard test and helps to determine the negative appendectomy rates which is regarded as the quality indicator of the treating centre.
The Need of Financial Literacy Proficiency Level for Generation Z Students at School
Authors: Prihartanti Frederika Widi , Murtini Wiedy , Indriayu Mintasih
Published: March 2022

Financial Literacy has a significant role in the individual decision-making process. Existing studies have proven that that lower levels of financial literacy lead to irrational financial decisions funds as well as savings and debt. Basically, Indonesian students in PISA 2018 have the lowest mean scores compared to other countries. At the same time, there is no integration in Indonesia curriculum with financial education. This study focuses on a review of financial education used in the current literature as well as their corresponding limitations.
Case Report ; Management of Chronic Periodontitis After 2 Months of Traffic Accidents
Authors: Maksmara Heru
Published: March 2022

The availability of domestic raw materials is gradually decreasing, while the need for energy sources is increasing. Therefore, it is necessary to have the availability of renewable energy sources, one of which is biomass. In this study, researchers will discuss the waste of sugarcane bagasse and orange peel which can be used as briquettes. Usually, these wastes are only used as animal feed, sometimes they are just thrown away. The goals and benefits expected by the author in this study are, to provide information that the manufacture of briquettes from bagasse and Pacitan orange peel can be used as an alternative fuel. So, it can be implemented to reduce fossil fuels, whose availability is getting less and less. In the study, the best results were on the adhesive variable 20% ratio 1:2 with a calorific value of 5,949,114 cal/gram, 9% moisture content, 9% ash content.
Pancasila Has the Ability to Improve Community, Nation, and State Life in the Twenty-First Century
Authors: Wen Lee Cheng- , Ande Taufiqquddin
Published: March 2022

The world was shocked by the uncertainty surrounding the end of the COVID-19 epidemic, which had an impact on socio-economic inequality that claimed lives, especially in Indonesia. Pancasila is the basis of the Unitary State of the Republic of Indonesia and is the philosophy and way of life of the Indonesian nation. The purpose of this research is to reflect the soul and personality of the Indonesian people, making them more resilient and creative in dealing with the COVID-19 pandemic and able to improve the life of society, nation and state. This study uses a literature study approach that collects various data and facts from several documents related to the research problem. Based on the results of research, national values, such as religious values, human values, and harmony values, can be used as guidelines for behavior and attitudes in dealing with difficulties in the COVID-19 area.
REMOTE DONOR PRECONDITIONING FOR INCREASING TRANSPLANT SURVIVAL IN THE RECIPIENT’S BODY DURING THE KIDNEY TRANSPLANTATION FROM THE LIVING-RELATED DONOR
Authors: Kyrychenko Maryna I. , Biliaiev Andriy V. , Mazur Andriy P.
Published: March 2022

The aim: To estimate the protective effect of remote ischemic preconditioning (RIPC) on kidney transplants harvested from living related donors.
Materials and methods: To achieve the claimed aim, there were examined 60 donor-recipient couples, where kidney transplant donors were living-related. All donors had the same anaesthetic management. The first group (n = 30) received RIPC which included four procedures of cuff inflations each lasting 5 minutes followed by 5-minute intervals of cuff deflation to measure blood pressure up to 40 mm Hg above systolic blood pressure on the shoulder. Patients of the second group (controls) did not experience RIPC (n = 30) and control group without RIPC.
Results: RIPC resulted in a statistically significant (P<0.05) increase in GFR of the transplanted kidney from 66±5 mL /min to 63±4 mL /min after 3 months, from 69±3 mL /min to 61±5 mL /min after 6 months, from 63±2.5 mL /min to 57±3 mL /min after 12 months; a 3-fold reduced partial delay of graft function; a 2-fold decreased incidence of acute kidney transplant rejection times; 1.5-fold decline in the incidence of primary non-function; and 1.4-fold tCr50 acceleration (p = 0.16). The follow-up period lasted for a year after transplantation.
Conclusions: RIPC during organ harvesting improved graft ischemic protection and increased functioning efficiency in the recipient.
RESULTS OF THE ANALYSIS OF ONCOLOGICAL COMPLICATIONS OF ANTI-TUMOR TREATMENT IN PATIENTS WITH THYROID CANCER ON THE BASIS OF MATHEMATICAL ANALYSIS OF THE CATAMNESTIC DATA
Authors: Vasyliev L.Ya. , Radzishevska Yev.B. , Savchenko A.S. , Vygivska L.A. , Radzishevska Ya.K. , Boiko O.M.
Published: March 2022

The aim: Identification of new, non-trivial knowledge on the prediction of thyroid recurrence on the basis of follow-up data from medical histories.
Materials and methods: The development of long-term oncological effects was studied on the catamnestic data of 157 patients diagnosed with thyroid cancer who were treated according to a standard scheme, including radical surgery, radioiodine therapy and hormone therapy.
Results: It is shown that the specificity of thyroglobulin as a cancer marker for thyroid cancer is not an unambiguous question and the probability of obtaining false-positive results on its basis is quite significant.
It is shown that violation of the recommended terms for special treatment (surgical and radioiodine therapy) can be used as a factor in the prognosis of relapse, and patients who received special treatment with violation of the terms for various reasons require careful attention and more careful examination. The dose of thyroxine that should be used to achieve suppression can be used as a marker of thyroid relapse: an excess of thyroxine levels of 2.8 μg / kg is an indicator of the risk of relapse in the future.
Statistically there was no significant effect on the prevention of long-term oncological complications by prolonging the duration of suppressive hormone therapy as a component of thyroid cancer treatment, but there are grounds to believe that prolonged suppression leads to increased cardiovascular and female genital complications.
Conclusions: the use of modern information technologies in relation to the arrays of catamnestic data of medical histories allowed to obtain additional knowledge to prevent the development of distant oncological complications resulting from thyroid cancer.
STUDY OF IMMUNO-PATHOGENETIC FEATURES OF PSORIASIS AND ACNE’S COURSE
Authors: Dashko Marianna , Syzon Orysya , Voznyak Iryna , Chaplyk-Chyzho Iryna
Published: March 2022

The aim: The objective of our work was to improve the diagnostics of common chronic dermatoses (acne, psoriasis, АР) taking into account some indicators of the immune system and features of the disease course to specify their role in pathogenesis of these disease.
Materials and methods: A total of 114 patients with acne and 128 patients with psoriasis were observed.
Results: Regardless of the disease duration period, we have detected in blood serum of psoriasis рatients probable changes in concentrations of stress-response mediators (decreased parameters of cellular immunity (CD3+, CD3+CD4+, CD3+CD8+ of T-lymphocytes, CD22+ fraction of B-lymphocytes and compensatory increased CD16+ of T-cells, cytokines – IL-1β, IL-8, IL- 17, IL-22, immunoglobulins IgM, IgG, and CIC), which indicate tension of their stress-induced mechanisms even despite occasional clinical stabilization of skin and articular process. Consequently, most of the patients with acne had varying degrees of changes in rates of systemic immunity. The most significant changes in rates of systemic immunity with the depletion of T-cell immunity were found in patients with papular-pustular and pustular acne, and still more significant – in patients with acne conglobate.
Conclusions: In patients with acne and psoriasis, changes in systemic immunity indexes that indicate the formation of secondary immunodeficiency state T-cell link, amid an adequate humoral immunity have been found. Relationship between the causes of changes of systemic immunity has been established.
CO-OCCURRING NECK-PAIN WITH MYOFASCIAL DYSFUNCTION IN PATIENTS WITH EPISODIC MIGRAINE
Authors: Chernenko Anna , Dubenko Olga , Kovalenko Liudmyla , Nessonova Tetyana
Published: March 2022

The aim: To determine the influence of co-occurring neck pain with cervical myofascial dysfunction on the development of psychoemotional disorders and the number of analgesics taken in patients with episodic migraine.
Materials and methods: The study included 92 patients, 24 male and 68 female, mean age 42.5±15.5 years. Three groups were identify based on type headache: 1) both episodic migraine and cervicogenic headache with neck pain; 2) episodic migraine only; 3) neck pain only. Visual analogue scale (VAS) for pain syndrome, Migraine Disability Assessment (MIDAS) score, Headache Impact Test (HIT-6), Neck Disability Index, State-Trait Anxiety Inventory (STAI), Beck’s Depression Inventory (BDI) and numbers days with analgesics intake were assessment.
Results: In patients, who suffered on episodic migraine combine with cervicogenic headache and neck pain number days with headache was more (p=0.000052), intensity attack was higher (p=0.003750) and number days with analgesics intake was greater (p=0.000003), compare with group with migraine only. The depression and anxiety state was more significant in patients with migraine and co-occurring neck pain comparable with migraine alone, but we found no significance differences between groups with migraine with neck pain and neck pain only. We observed significant correlation between STAI and Neck Disability Index (r=-0.5155), Neck Disability Index and HIT-6 (r=-0.4819). No correlation found between VAS for migraine, MIDAS and STAI and BDI.
Conclusions: Our study demonstrate, that co-occurring neck pain in patients with episodic migraine increasing of numbers days with headache, negatively impacts on mood disorders, daily activity and associated with greater acute analgesics use.
EVALUATION OF BACTERIAL CONTAMINATION IN THE INANIMATE ENVIRONMENT SURFACES IN ACUTE CARE HOSPITALS IN KYIV, UKRAINE
Authors: Salmanov Aidyn G. , Shchehlov Dmytro V. , Svyrydiuk Oleh , Bortnik Ihor M. , Mamonova Maryna , Krylova Anna S. , Gudym Maxim S.
Published: March 2022

The aim: To evaluate the quality of cleaning and disinfection of surfaces scheduled for daily cleaning and degree of bacterial contamination of hospital rooms and the patients’ inanimate environment in Kyiv acute care hospitals, Ukraine.
Materials and methods: We performed a multicenter prospectively study of the quality of cleaning and disinfection of surfaces scheduled for daily cleaning in 9 acute care hospitals by use of an ultraviolet fluorescence targeting method and microbial methods.
Results: A total 9,104 environmental samples from were collected and tested. The cleaning and disinfection of surfaces were not being performed properly in most cases. Complete removal of the mark was 49.1%, partial removal was 37,5%, and mark was still visible, i.e. this area had not been processed was 13,4% when the ultraviolet fluorescence targeting method procedures were used, respectively. The predominant bacterial agents in hospital environment surfaces were: Escherichia coli, Enterobacter spp., Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus spp., Citrobacter spp., Acinetobacter spp., and Enterococcus spp. The overall proportion of extended spectrum beta-lactamase (ESBL) production among Enterobacteriaceae was 31.5% and of methicillin-resistance in Staphylococcus aureus (MRSA) 14.9%. Vancomycin resistance was observed in 5.2% of isolated enterococci (VRE). Resistance to third-generation cephalosporins was observed in 12.7% E.coli isolates and was in 11.2% K. pneumoniae isolates. Carbapenem resistance was identified in 24.7% of P.aeruginosa isolates and 59.3% of Acinetibacter spp. isolates.
Conclusions: In a hospital rooms, patient environmental surfaces can be a vehicle for the transmission of multidrug-resistant (MDR) bacterial agents that cause healthcare-associated infections.
COMPARATIVE ANALYSIS OF CLINICAL AND LABORATORY CHARACTERISTICS OF MEASLES IN VACCINATED AND UNVACCINATED CHILDREN IN THE POLTAVA REGION (UKRAINE)
Authors: Ilchenko Valentyna I. , Syzova Liudmyla M. , Pikul Каteryna V. , Dvornyk Irynа L. , Muravlоva Oksana V.
Published: March 2022

The aim: To study the clinical and laboratory characteristics of measles, as well as to compare the course of this disease in vaccinated and unvaccinated children in the Poltava region (Ukraine).
Materials and methods: 104 inpatients with measles were examined: vaccinated (n=27) and unvaccinated (n=77). The patient examination program included: assessment of complaints and anamnestic data obtained by questioning (during admission to hospital treatment, during treatment and after discharge) and detailed analysis of medical records (Form № 003/у), physical examination, general clinical study of peripheral blood.
Statistical processing of the study results was carried out by methods of variation statistics using the program «SPSS 17.0».
Results: The clinical and laboratory picture of measles in the examined patients is typical for this disease. Measles vaccinated children are significantly less likely to have fever (р=0.001) and Koplik’s spots (χ2=3.80, р=0.051), the duration of fever (р=0.001), cough (р=0.000), and the length of hospital stay (р=0.000), as well as 3.0 times less often leukopenia is detected (р=0.043) and 2.0 times less often − acceleration of ESR (р=0.023).
Conclusions: The obtained data raise the question of expanding the explanatory work on the importance of a full course of preventive vaccination among children, as well as increasing the volume of public procurement of necessary drugs to increase public access to free vaccination.
ECOLOGICAL EDUCATION AND ITS RELATIONSHIP WITH STUDENTS’ HEALTH
Authors: Griban Grygoriy P. , Okhrimenko Ivan М. , Myroshnychenko Mykhailo S. , Tomenko Oleksandr A. , Matrosov Serhii O. , Rohovenko Mariia M.
Published: March 2022

The aim is to assess the state of ecological education in student youth and determine its relationship to the level of students’ health.
Materials and methods: The research was conducted on the basis ofthe Polissya National University (Zhytomyr, Ukraine) and the Sumy State Pedagogical University named after A.S. Makarenko (Sumy, Ukraine) in 2018-2020. The ascertaining experiment, which was conducted to assess the state of ecological education of students according to the questionnaire developed by us involved 503 students. The formative experiment aimed at studying the relationship between the level of ecological education and the level of students’ health involved 59 students.
Results: The ascertaining stage of the experiment showed that the vast majority of students of different specialties revealed a low level of mastery of the components of ecological education. The formative stage of the experiment showed that the EG students significantly improved the level of all components of ecological education, as well as the level of their health (p < 0.001). No significant changes were revealed in the CG (p > 0.05).
Conclusions: The research showed that purposeful work on the formation of ecological education in the process of fitness and health recreation activities has a positive effect on all its components (knowledge, character building, worldview, culture) and the level of students’ health. In general, it will help to improve the efficiency of the educational process of students, improve indicators of their life-sustaining and future professional activities.
THE EFFECT OF NOS3 AND AGTR1 GENOTYPES ON THE COURSE OF THE ARTERIAL HYPERTENSION FOR THE OVERWEIGHT OR OBESE PATIENTS
Authors: Potaskalova Viktoriia S. , Khaitovych Nick V. , Natrus Larysa V. , Abdriakhimova Tsira B. , Kleban Kateryna I. , Lunov Vitalii Y. , Korop Oleg A.
Published: March 2022

The aim: Objective of the research is to determine the effect of NOS3 and AGTR1 genotypes of patients with arterial hypertension and high body mass index in the course of the disease. Materials and methods: 58 patients (22 men and 36 women) with AH and high BMI were examined. The average age of the examined patients was 53.6±8.7 years. The analysis of rs1799983 polymorphisms of the NOS3 gene (localization 7q36.1; 7:150999023) and AGTR1 (type 1 receptor for angiotensin 2 1166 A>C) was performed using TaqMan assay (Thermo Fisher Scientific, USA) by real-time PCR (Applied Biosystems, USA) using TaqMan probe amplification products. Genomic DNA samples were isolated from stabilized blood using a Genomic DNA Mini Kit reagent (Invitrogen, USA). The Statistica 10 program (StatSoft Inc.) was used for statistical processing of the obtained data, USA). The independent samples were compared using the Mann-Whitney (U) criterion. In all cases of statistical evaluation, the reliability of differences was taken into account at a value of p<0.05. Results and conclusions: Polymorphism of the NOS3 and AGTR1 genes is associated with early development and complicated course of cardiovascular pathology. The combination of NOS3 and AGTR1 gene polymorphism in patients with the high body mass index increases the risk of complications in hypertension. Using a mathematical model to predict the probability (95%) of genetic mutations in two genes (NOS3 and AGTR1) increases the effectiveness of diagnosis for patients with the high risk of developing cardiovascular complications.
THE USE OF ULTRASOUND GUIDED HIGH INTENSITY FOCUSED ULTRASOUND (HIFU) IN THE TREATMENT OF UTERINE FIBROIDS: AN OVERVIEW
Authors: Ivanova Yoana , Dimitrov Dobromir , Dimitrova Kameliya , Shanker Aparajeya , Yordanov Angel
Published: March 2022

Uterine fibroids are the most common benign gynecological neoplasms, with a higher prevalence in women aged between 30 and 50 years old. Fibroids may be asymptomatic, but in some cases, they can affect seriously the quality of life of the patients. In some cases, we can recommend expectant management for asymptomatic patients. Management depends on the size and location of fibroids, the age of the patient, symptoms, desire for future childbearing and the experience of the gynecologist. Medical therapy includes hormonal contraceptives, tranexamic acid, and nonsteroidal anti-inflammatory drugs (reduce heavy menstrual bleeding). Gonadotropin-releasing hormone agonists or selective progesterone receptor modulators are used mostly preoperatively. Surgical treatment includes hysterectomy, myomectomy – invasive and minimally invasive. Non-surgical management include uterine artery embolization, and focused ultrasound surgery.This review aims to present the role of High-Intensity Focused Ultrasound in the treatment of uterine fibroids.
PRINCIPLES OF DIAGNOSIS AND TREATMENT OF ASKIN’S TUMOR IN CHILDREN: CASE REPORT
Authors: Korol Tatiana G. , Blazhko Serhii S. , Rudenko Hennadii M. , Khromykh Kateryna
Published: March 2022

The aim of the study was to show principles of diagnosis and treatment of Askin’s tumor in children. Diagnostic procedures include physical examination, chest X-ray, CT scan and PET CT, morphological, histological and immunohistochemical examinations, cytogenetic study. Primitive neuroectodermal tumors belong to the group of low differentiated, overly aggressive neoplasms, originating from cells of the parasympathetic autonomic nervous system. Patient F., 9 years old, first consulted by pediatric oncologist in 2014 with complaints of volume formation in the chest on the right side which progressively increases. Diagnosis: PNEP (primitive neuroectodermal tumor) of the soft tissues of the chest on the right side in the 4th intercostal space along the midclavicular line T2aN0M0, stage 2a, standard risk group. We’ve shown results of diagnostical process, treatment and it’s result in our patient. Patients who have received combination therapy, including chemotherapy, surgical removal of the tumor and radiation therapy, have better prognostic results. However, relapses often occur that require more aggressive treatment with high-dose chemotherapy, monoclonal antibodies, and bone marrow transplantation.