bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Orthodontic Appliances in Alleviating Temporomandibular Joint Disorders - An Overview
Authors: Ponnukumar Akash , Sakthivel Preethika , Ammayappan Pavithranand
Published: November 2024

The mandibular joint is a condyloid synovial joint, that is formed between the head of the mandible and the petrous temporal bone. Temporomandibular disorders (TMDs) occur in roughly one out of four people; they are degenerative musculoskeletal diseases that cause morphological and functional alterations, characterized by pain, restricted mouth opening, and clicking sounds. Basically, the causes of TMD are genetic predisposition, trauma, arthritis, and dental malocclusion. TMD is rooted in early Egypt manual therapy, Hippocrates, and early surgeons such as Annandale, Lanz, Pringle, and Wakeley. The National Institutes of Health sponsored an international workshop in 1994 to initiate the research and nevertheless consensus of TMD. The American Academy of Orofacial Pain has divided TMD into muscle TMD or myogenous and joint TMD or arthrogenous TMD. Studies are in agreement that orthodontic treatment may help in alleviating TMD. The systematic review showed that patients undergoing orthodontic treatment reported a decrease in their TMD symptoms and headaches. TMD treatment is generally carried out in two stages: Phase I, intraoral orthopedic appliances, phase II, occlusal adjustment, or further large case procedures. They include splints that are commonly used but produce negative effects whenever the splints are designed wrongly or used for an unusually long time. Fixed removable appliances such as stabilization and anterior positioning appliances are applied in treating TMD. Stabilization appliances deal primarily with muscle pain and parafunctional activities, while anterior positioning appliances are useful in cases of disc derangement disorders, they aid in the proper positioning of the condyle and disc. Their usage needs specific criteria to be fulfilled for them to be effective. Although there is continuing controversy and uncertainty about certain aspects of the results of studies for now, oral appliances belong to the most conservative type of TMD therapy. They afford relief from the symptoms and are akin to orthopedic braces without aiming at creating new occlusal erections. Further studies are required to provide more accreditation on treatment regimens and patients’ conditions.
Nutritional Care: Nurses’ Critical Role in Improving Patient Outcomes
Authors: Gomathi B.
Published: November 2024

Nutrition is an essential component of general health and well-being. In the clinical environment, the multidisciplinary team plays a fundamental role in meeting patients’ nutritional requirements. Of these professionals, nurses hold a great position because they are continually present at the bedside with the patient, directly engage with the patients, and spend hours interacting with them. This review discusses nurses’ critical roles in assessing, intervening, and monitoring nutrition care and provides examples of best practices. For instance, nurses are the first to clinically identify patients’ nutrition problems. A wide range of assessment tools and methods is used when a nurse assesses a patient’s nutritional status. While doing a routine assessment of the patient’s vital signs, a nurse may notice changes in weight and diet that may indicate some malnutrition. Nurses can systematically identify those at risk of malnutrition and intervene early by implementing standardized nutrition screening tools such as the subjective global assessment or the Malnutrition Universal Screening Tool.

Interventions:

Once a nutrition diagnosis is identified, nurses work with other physicians and registered dietitians to develop an evidence-based intervention plan. For example, a nurse may support the delivery of enteral or parenteral nutrition by ensuring that required equipment, such as nasogastric tubes or peripherally inserted central catheters, is used correctly. Nurses may support intervention by changing the texture of food, modifying the presentation for meals, or teaching patients how to eat.

Monitoring Nutrition Outcomes:

There is a need to monitor the outcomes of nutrition interventions that have been implemented so that a patient can attain optimal nutrition outcomes. This involves monitoring food intake, laboratory results, and weight gains/losses and adjusting care plans appropriately. The laboratory values may include hemoglobin or serum proteins. A few best practices can help nurses better work on nutritional care concerns. Some of them include establishing and implementing standardized protocols for nutrition screening and continuous education in conducting nutrition assessments and interventions. Increasing the availability of resources such as registered dietitians in hospitals will ensure that patients have comprehensive nutritional care plans suited to their special needs.
A simple, economical, and high-yield method for polyethylene glycol-based extraction of follicular and serum-derived extracellular vesicles
Authors: Khine Aye Aye , Chen Pao-Chu , Chen Ying-Hsi , Chu Sung-Chao , Chen Yu-Shuan , Huang Hsuan-Shun , Chu Tang-Yuan
Published: November 2024

ABSTRACT

Objectives:

The optimization of polyethylene glycol (PEG)-based extracellular vesicles (EVs) extraction from human follicular fluid (FF) and serum was investigated, and their functional analysis was confirmed. The PEG-based EV results were compared to the ExoQuick (ExoQ)-based EV.

Materials and Methods:

FF-EVs and serum-EVs were extracted by using different concentrations of PEG (8000). Nanoparticle tracking analysis was used to count the particles, and electron microscopy of EVs was performed for visualization. Exosomes were confirmed by the western blot analysis with exosome-specific markers. RNA and microRNA were extracted from exosomes and quantitative polymerase chain reaction analysis was performed. Fallopian tube epithelial (FTE) cells were used for the EV uptake experiment and an anchorage-independent growth test to confirm that extracted EVs harbor transformation activity.

Results:

The PEG 8% enriched method produced the highest yield and the lowest carry-over protein. Salt containing PEG 8% produced a higher yield than nonsalted PEG 8%. Overnight enrichment increased four times and 18 times for PEG 8% and ExoQ-based EV extraction from FF. For serum EV, the same overnight enrichment moderately increased yield for both PEG 8% and ExoQ methods. Less carry-over protein resulted in more EV-promoted transformation activity.

Conclusion:

This study overcomes the time-consuming, expensive, laborious, and complicated machine-dependent EV extraction methods. The study highlights that longer incubation time is needed for EV extraction from FF. PEG 8000-based EV extraction provided a higher yield and less carry-over protein than ExoQ-based EV extraction.
Early detection of bloodstream infection in critically ill children using artificial intelligence
Authors: Han Hye-Ji , Kim Kyunghoon , Park June Dong
Published: November 2024

Background: Despite the high mortality associated with bloodstream infection (BSI), early detection of this condition is challenging in critical settings. The objective of this study was to create a machine learning tool for rapid recognition of BSI in critically ill children.Methods: Data were extracted from a derivative cohort comprising patients who underwent at least one blood culture during hospitalization in the pediatric intensive care unit (PICU) of a tertiary hospital from January 2020 to June 2023 for model development. Data from another tertiary hospital were utilized for external validation. Variables selected for model development were age, white blood cell count with segmented neutrophil count, C-reactive protein, bilirubin, liver enzymes, glucose, body temperature, heart rate, and respiratory rate. Algorithms compared were extra trees, random forest, light gradient boosting, extreme gradient boosting, and CatBoost.Results: We gathered 1,806 measurements and recorded 290 hospitalizations from 263 patients in the derivative cohort. Median age on admission was 43 months, with an interquartile range of 10–118.75 months, and a male predominance was observed (n=160, 55.2%). Candida albicans was the most prevalent pathogen, and median duration to confirm BSI was 3 days (range, 3–4). Patients with BSI experienced significantly higher in-hospital mortality and prolonged stays in the PICU than patients without BSI. Random forest classifier achieved the highest area under the receiver operating characteristic curve of 0.874 (0.762 for the validation set).Conclusions: We developed a machine learning model that predicts BSI with acceptable performance. Further research is necessary to validate its effectiveness.
Left ventricle unloading during veno-arterial extracorporeal membrane oxygenation: review with updated evidence
Authors: Lim Yongwhan , Kim Min Chul , Jeong In-Seok
Published: November 2024

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is widely used to treat medically refractory cardiogenic shock and cardiac arrest, and its usage has increased exponentially over time. Although VA-ECMO has many advantages over other mechanical circulatory supports, it has the unavoidable disadvantage of increasing retrograde arterial flow in the afterload, which causes left ventricular (LV) overload and can lead to undesirable consequences during VA-ECMO treatment. Weak or no antegrade flow without sufficient opening of the aortic valve increases the LV end-diastolic pressure, and that can cause refractory pulmonary edema, blood stagnation, thrombosis, and refractory ventricular arrhythmia. This hemodynamic change is also related to an increase in myocardial energy consumption and poor recovery, making LV unloading an essential management issue during VA-ECMO treatment. The principal factors in effective LV unloading are its timing, indications, and modalities. In this article, we review why LV unloading is required, when it is indicated, and how it can be achieved.
Isolated reversible mydriasis was associated with the use of nebulized ipratropium bromide: a case series using quantitative pupilometer in Korea
Authors: Park Soo-Hyun , Kim Tae Jung , Ko Sang-Bae
Published: November 2024

Background: Abnormal pupillary reactivity is a neurological emergency requiring prompt evaluation to identify its underlying causes. Although isolated unilateral mydriasis without accompanying neurological abnormalities is rare, it has occasionally been associated with nebulizer use. We aimed to quantitatively assess pupillary changes using a pupillometer in cases of isolated mydriasis, which has not been described in previous studies.Methods: We retrospectively analyzed patients who developed unilateral mydriasis after using an ipratropium bromide nebulizer using a prospectively collected database in the intensive care unit (ICU) between April 2019 and August 2020. An automated pupillometer (NPi-100 or NPi-200) was used for quantitative pupillary assessment. The Neurological Pupil index (NPi) value at the time of unilateral mydriasis was assessed, and the latency before and after the application of the ipratropium bromide nebulizer was measured.Results: Five patients with isolated mydriasis were identified (mean age, 68 years; male, 60.0%), none of whom had neurological abnormalities other than pupillary light reflex abnormalities. A quantitative pupillometer examination revealed that the affected pupil was larger (5.67 mm vs. 3.20 mm) and had lower NPi values (0.60 vs. 3.40) than the unaffected side. These abnormalities resolved spontaneously without treatment (pupil size, 3.40 mm; NPi, 3.90). The affected pupil had a prolonged latency of 0.38 seconds (vs. 0.28 seconds), which improved to 0.30 seconds with the resolution of the anisocoria.Conclusions: In the ICU setting, it is important to keep in mind the ipratropium bromide nebulizer as the benign cause of unilateral mydriasis. Further, an automated pupilometer may be a useful tool for evaluating unilateral mydriasis.
Documenting Trends in Malaria Data Reporting Accuracy Using Routine Data Quality Audits in Zambia, 2015–2022
Authors: Das Smita , Roca Feltrer Arantxa , Rutagwera Marie-Reine I. , Lungu Christopher , Malama Prudence , Monde Mathews , Banda Ignatius , Ingwe Mercy M. , Hamainza Busiku , Bennett Adam , Hainsworth Michael
Published: November 2024

Since 2015, the Zambia National Malaria Elimination Centre has conducted routine data quality audits in Central, Southern, and Western provinces, but trends in data reporting accuracy have not been examined. Routine data quality audit data collected at health facilities reporting into the monthly health management information system (HMIS) and weekly malaria rapid reporting system (MRRS) were used to measure data reporting accuracy trends from 2015 to 2022 and potential influencing factors using three data elements: outpatient department attendance and rapid diagnostic test (RDT)-tested cases for HMIS and MRRS, total confirmed cases for HMIS only, and RDT-positive cases for MRRS only. Reporting accuracies for HMIS and MRRS data elements and the percentage of facilities reporting with high accuracy (≥85%) improved over this period. Low-accuracy (<70%) health facilities were uncommon, accounting for less than 15% of facilities for HMIS and MRRS. With each successive DQA visit, the proportion of facilities with high accuracy increased from visits 1 to 8: 23% to 56% (HMIS) and 42% to 85% (MRRS). No correlation was observed between facility size or incidence and overall accuracy for HMIS and MRRS. Starting in 2017, about 40–50% of health facilities appeared to be overreporting incidence in comparison with their register-based incidence. The risk stratification determined by register-based and reported incidences matched in more than 70% of facilities. Routine data quality audits conducted between 2015 and 2022 in Central, Southern, and Western provinces showed an improvement in malaria data reporting accuracy.
Pancreatic volume change using three dimensional-computed tomography volumetry and its relationships with diabetes on long-term follow-up in autoimmune pancreatitis
Authors: Shimada Ryuichi , Yamada Yasunari , Okamoto Kazuhisa , Murakami Kazunari , Motomura Mitsuteru , Takaki Hajime , Fukuzawa Kengo , Asayama Yoshiki
Published: November 2024

BACKGROUND

Several studies found that early pancreatic atrophy detected by computed tomography (CT) within 6 months was associated with a high incidence of diabetes in patients with type-1 autoimmune pancreatitis (AIP) receiving steroid therapy; however, no long-term follow-up studies have been performed.

AIM

To investigate pancreatic volume (PV) changes using three dimensional (3D)-CT volumetry and their relationship with IgG4 and diabetes in patients with AIP.

METHODS

This retrospective study included 33 patients with type-1 AIP receiving steroid therapy. Patients were divided into diffuse (D-type) and mass-forming type (M-type) AIP. PV was determined by semi-automated 3D-CT volumetry, and changes between initial and follow-up values were calculated. The relationship between PV and serum IgG4 levels was analyzed by Spearman’s rank correlation. The PV atrophy ratio compared with the presumed normal PV at the time of last follow-up CT and its relationship with diabetes were investigated.

RESULTS

There were 16 D-type and 17 M-type patients with long-term follow-up (mean, 95.8 months). The regression curve of mean relative PV change reduced exponentially and rapidly during the first 25 months and then more slowly in both groups. The overall cumulative pancreas re-enlargement rates at 1, 3, 5, 7 and 10 years were 6.1%, 12.2%, 29.2%, 47.5% and 55.0%, respectively. There was a moderate-to-very strong positive correlation (ρ ≥ 0.4) between PV and serum IgG4 levels in nine (9/13, 69.2%) patients. All 33 patients showed pancreatic atrophy (mean 59.3%) after long-term follow-up. Patients with D-type AIP had a significantly higher atrophy rate and higher incidence of diabetes than M-type patients (P < 0.05).

CONCLUSION

PV change initially reduced exponentially and then more slowly and is considered an important factor associated with diabetes. Serum IgG4 levels were positively correlated with PV during follow-up.
Opis granic wsi Czeluśnica, Gąsówka i Umieszcz pod koniec XVIII w. w świetle pierwszego austriackiego katastru nieruchomości
Authors: Bodaszewski Jakub
Published: November 2024

Celem artykułu jest opisanie pomiarów katastralnych przeprowadzanych przez władze zaborcze austriackie w 1787 r. na podstawie zapisów z metryki józefińskiej z 1787 r. dla miejscowości Czeluśnica, Gąsówka i Umieszcz w dzisiejszym powiecie jasielskim. Ukazano nie tylko ustalanie przebiegu granic wsi, ale i poruszono kwestie dotyczące znaków granicznych, osób uczestniczących w komisjach pomiarowych oraz sposobów spisywania granic i ich uprawomocniania. Zwrócono uwagę na kierunek rozpoczynania pomiarów oraz słabo zbadaną sprawę tzw. świadków granicznych. Niniejszy artykuł, przy braku ksiąg metrykalnych, może stanowić także przyczynek do badań genealogicznych oraz geografii historycznej.

Description of the Czeluśnica, Gąsówka and Umieszcz village borders at the end of the 18th century in the light of the first Austrian real estate cadastre:

The aim of the article is to describe the cadastral measurements carried out by the Austrian authorities in 1787 based on entries from the Josephine register of 1787 for the villages of Czeluśnica, Gąsówka and Umieszcz in today’s Jasło district. It shows not only how the village borders were established, but also raises issues related to border signs, people participating in measurement commissions and ways of recording borders and validating them. Attention is paid to the direction of starting the measurements and the poorly researched case of the so-called border witnesses. This article, in the absence of record books, can also be a contribution to genealogical research and historical geography.
Krakowskie winiety papierów firmowych jako źródło historyczne (połowa XIX – początek XX w.). Zarys problematyki
Authors: Follprecht Kamila
Published: November 2024

Od połowy XIX w. jako formę reklamowania oferowanych usług czy produktów zaczęto wprowadzać na szerszą skalę ozdobny papier firmowy, w winiecie którego umieszczano zazwyczaj podstawowe informacje: imię i nazwisko właściciela, nazwę firmy, a niekiedy datę jej powstania, adres siedziby firmy oraz ewentualnych oddziałów lub filii. Z czasem zaczęto też podawać nr telefonu, nr konta bankowego, możliwe formy płatności. Jako elementy ozdobne stosowano motywy ornamentalne, figury alegoryczne, atrybuty rzemiosł, wizerunki asortymentu, medali uzyskanych na prestiżowych konkursach, dyplomów, nagród czy certyfikatów, a także przedstawienia architektoniczne budynków i zespołów przemysłowych. Zachowane w zasobie Archiwum Narodowego w Krakowie zbiory papierów firmowych od połowy XIX w. do 1918 r. są datowane, co umożliwia śledzenie częstotliwości i charakteru wprowadzanych zmian, odzwierciedlających dzieje firmy. W artykule przedstawiono analizę papierów firmowych z winietami znanych firm Maurycego Barucha (1800–1874) i jego synów Emila (1832–1886) i Gustawa (1838–1907), działających w Podgórzu i Łagiewnikach. Na podstawie zachowanych papierów firmowych z winietami oraz reklam zaprezentowano także działającą w rynkowej kamienicy w Krakowie w latach 1878–1917 firmę blacharską Władysława Kosydarskiego (1851–1919).

Kraków letterheads as a historical source (mid-19th century – early 20th century). Outline of the subjects:

From the mid-nineteenth century, as a way of advertising offered services or products, decorative letterheads were introduced on a larger scale, with the vignette usually including basic information: the owner’s full name, the company name, and sometimes the date of its establishment, address of the company’s headquarters and branches. Over time, the phone number, bank account number, and possible forms of payment were also provided. Ornamental motifs, allegorical figures, attributes of crafts, images of the assortment, medals obtained at prestigious competitions, diplomas, awards or certificates, as well as architectural representations of buildings and industrial complexes were used as decorative elements. The collections of letterheads from the mid-nineteenth century to 1918, preserved in the National Archives in Krakow, are dated, making it possible to track the frequency and nature of the introduced changes, reflecting the company’s history. The article presents an analysis of letterheads with vignettes of the well-known company of Maurycy Baruch (1800–1874) and his sons, Emil (1832–1886) and Gustaw (1838–1907), operating in Podgórze and Łagiewniki. Based on the preserved letterheads with vignettes and advertisements, the sheet metal company of Władysław Kosydarski (1851–1919) operating in a tenement house in Kraków’s Market Square in the years 1878–1917 is also presented.
Stypendysta Akademii. Związki Tadeusza Smoleńskiego (1884–1909) z Akademią Umiejętności
Authors: Wilk Bernadeta
Published: November 2024

Celem artykułu jest zaprezentowanie relacji Tadeusza Smoleńskiego z Akademią Umiejętności, dzięki wsparciu której mógł poszerzać wiedzę o starożytnym Egipcie. T. Smoleński studiował historię i geografię na Uniwersytecie Jagiellońskim. W 1904 r. lekarze zdiagnozowali u niego chorobę płuc, co zmusiło go do przerwania nauki i podjęcia leczenia klimatycznego w Egipcie. W Kairze rozpoczął studia z archeologii i filologii egipskiej pod kierunkiem Gastona Maspero. Trudna sytuacja materialna w kraju faraonów skłoniła go do zwrócenia się o pomoc do Bolesława Ulanowskiego, sekretarza generalnego Akademii Umiejętności. W latach 1905/1906, 1906/1907, 1907/1908 T. Smoleński otrzymał od zarządu Akademii Umiejętności stypendium z legatu Malwiny Jankowskiej w wysokości 600 koron austriackich rocznie. W 1907 i 1908 r. brał udział w dwóch austro-węgierskich ekspedycjach wykopaliskowych w Szarunie i El-Gamhud. Dzięki uczestnictwu młodego egiptologa w kampaniach wykopaliskowych nad Nilem Akademia Umiejętności otrzymała cztery sarkofagi z mumiami z El-Gamhud oraz dwie wapienne płyty z ptolemejskiej świątyni w Szarunie.

Academy Scholar. Relationships of Tadeusz Smoleński (1884–1909) and the Academy of Arts and Sciences:

The article aims to present Tadeusz Smoleński’s relationship with the Academy of Arts and Sciences, thanks to which he was able to expand his knowledge of ancient Egypt. T. Smoleński studied history and geography at Jagiellonian University. In 1904, doctors diagnosed him with lung disease, which forced him to stop studying and undergo climatotherapy in Egypt. In Cairo, he began studying archaeology and Egyptian philology under the guidance of Gaston Maspero. The difficult financial situation in the land of the pharaohs made him turn to Bolesław Ulanowski, secretary general of the Academy of Arts and Sciences. In the years 1905/1906, 1906/1907, and 1907/1908, T. Smoleński received a scholarship from the Academy of Arts and Sciences of 600 Austrian crowns a year from the bequest of Malwina Jankowska. In 1907 and 1908, he took part in two Austro-Hungarian excavation expeditions in Sharuna and El-Gamhud. Thanks to the young Egyptologist’s participation in the excavation campaigns on the Nile, the Academy of Arts and Sciences received four sarcophagi with mummies from El-Gamhud and two limestone slabs from the Ptolemaic temple in Sharuna.
Archiwa – oddziaływania i wartości
Authors: Wiśniewska-Drewniak Magdalena
Published: November 2024

Artykuł ma na celu zwrócenie uwagi na pozamaterialne aspekty związane z archiwaliami i archiwami, w szczególności archiwami społecznymi. Bazując na analizie literatury (szczególnie literatury zagranicznej) oraz posiłkując się wywiadami przeprowadzonymi z archiwistami społecznymi w latach 2015–2018, autorka krótko omawia zagadnienia wpływu społecznego archiwów społecznych oraz afektywnego oddziaływania archiwów na odbiorców, darczyńców i archiwistów, poruszając również kwestię traumy zastępczej.

Archives – impact and values:
The article aims to draw attention to non-material aspects related to archives, especially community archives. Based on the analysis of literature (especially foreign literature) and interviews conducted with community archivists in 2015–2018, the author briefly discusses issues regarding the social impact of community archives and the affective impact of archives on recipients, donors and archivists, also raising the issue of vicarious trauma.
The group constitution mechanism in the university environment
Authors: ȘCHIOPU Lucia
Published: November 2024

The article evokes the behavior of teaching staff within university departments/chairs, which depends on the influence of groups and structures within the university, whose objectives are the application of theoretical knowledge to make the educational process more efficient. The role of the group is important in satisfying individual needs in the participation of faculty members in groups such as: the needs of belonging, the needs of friendship, support, love, the needs of developing, strengthening or verifying the individual's sense of identity and maintaining self-respect , emotional needs, problem-solving needs.
Peran UU No. 22 Th. 1999 dan UU No. 25 Th. 1999 Terhadap Visi & Misi Bwi Bermartabat
Authors: Kusyana Kusyana , Walim Walim
Published: November 2024

UU No. 22 Tahun 1999 dan UU No. 25 Tahun 1999 menjadi dasar penting untuk mendukung tujuan Badan Usaha Milik Daerah (BUMD) di Indramayu, Jawa Barat, dalam melayani masyarakat sekaligus memperoleh keuntungan. Implementasi pemerintahan yang baik dilakukan melalui pembangunan ekonomi nasional yang merata hingga daerah. Berdasarkan UU No. 25 Tahun 1999 tentang Desentralisasi Fiskal, daerah berhak memperoleh sumber keuangan dari pengelolaan BUMD dan kerjasama dengan pihak ketiga. BUMD memiliki tiga misi utama: melayani masyarakat, sebagai sumber Pendapatan Asli Daerah (PAD), dan sebagai agen pembangunan ekonomi daerah. Di bawah UU No. 22 Tahun 1999, otonomi daerah bertujuan untuk meningkatkan kesejahteraan masyarakat dengan memanfaatkan sumber daya lokal. Pemerintah daerah perlu kreatif dan inovatif, mengombinasikan faktor ekonomi, kelembagaan publik, SDM, dan teknologi untuk meningkatkan daya saing daerah. Sumber pendapatan daerah mencakup pajak, laba BUMD, dan penerimaan lain, terutama karena berkurangnya subsidi pusat. Meskipun BUMD kurang strategis dibanding BUMN, mereka menghadapi tantangan dalam hal tata kelola, ketidaksetaraan perlakuan, minimnya modal, serta tekanan politik yang memengaruhi efisiensi modal. Penelitian ini menggunakan metode kualitatif.
Development of Informatics Science Towards Multimedia
Authors: Ariesta Wenno Leony , Ndahawali Nicholas , Al Buhari Galih Sava , Tombokan Devy , Surentu Mikael , Takasihaeng Marco
Published: November 2024

This research refers to the development of informatics and multimedia which has undergone a significant transformation, influencing various aspects of life, especially in the fields of education, business and communication. Multimedia, which is a combination of various elements such as text, images, audio, animation and video, has become an important means for convey information effectively and interestingly. The development of information technology, especially the Internet, has accelerated the popularity of multimedia. With the internet, access to various forms of multimedia has become easier, allowing users to learn independently and interactively. In the educational context, multimedia is used as an effective teaching tool, both in class and online, thereby improving the quality of learning and motivating students.
Pemolisian Kolaboratif dalam Penanganan Konflik Sosial: Studi Kasus Konflik Sara di Desa Mareje, Lombok Barat
Authors: Bayuanggoro Donny
Published: November 2024

This study discusses the application of collaborative policing in handling ethnic, religious, racial, and intergroup (SARA)-based social conflicts with a case study of conflict in Mareje Village, West Lombok, NTB, in 2021. Focusing on the qualitative method of case studies, this study analyzes the dynamics of interactions between the police, the community, and other stakeholders in handling conflicts. The results show that collaborative policing through cross-sector involvement is effective in reducing tensions and supporting post-conflict recovery. However, challenges in communication and synergy between parties are still obstacles in the implementation of this collaborative strategy. This study recommends increased multi-sector engagement and cross-sector collaboration to improve effectiveness in handling future SARA conflicts.
Prevalence of Malocclusion During Puberty Growth Spurt in Grade X Students of SMA Seven at Gunung Samarinda Health Center
Authors: Purwanti Helti , Junaedi Nafira , Luftiana Risanti Maulidya , Dzikri Akhmad , Wisnuwardhani Ratih Wirapuspita
Published: November 2024

Malocclusion is anabnormal position of the jaw or teeth. Malocclusion ranges in severity from low to high, reflecting biological differences across individuals. Human growth and development varies, including bone growth during the accelerated growth period during puberty. Individual identification of the pubertal growth spurt period is very important in orthodontic treatment, because the best growth changes are achieved during the pubertal growth spurt.Purpose: This Study aimed to describe the prevalence of Malocclusion in Pubertal growth Spurt at class 10  students of  7  Senior High School during networking at Gunung Samarinda Community Health Center, Balikpapan East Kalimantan.Methods: A descriptive observational study with a crosssectional design was conducted. There were 1339 students recruited in the screening session.
Efek Ekstrak Arbei (Rubus idaeus) terhadap Kadar Kolesterol Total Tikus Wistar Model Sindrom Metabolik
Authors: Hemawan Danus , Sarsono Sarsono
Published: November 2024

Metabolic syndrome is characterized by low HDL levels, high triglycerides, hypertension, increased blood glucose, and obesity, often associated with obesity and type 2 diabetes. This study aimed to investigate the effect of Wild Red Raspberry (Rubus idaeus) on total cholesterol levels in Wistar rats (Rattus norvegicus) with a metabolic syndrome model. Method This research employed a quantitative experimental laboratory study with a pretest-posttest control group design. A total of 30 male Wistar rats were divided into five groups: K1 (negative control), K2 (positive control), and K3, K4, K5 (metabolic syndrome) treated with Rubus idaeus extract at doses of 30 mg/200gBW/day, 60 mg/200gBW/day, and 90 mg/200gBW/day. Total cholesterol levels were measured on days 8, 36, and 64. Data analysis was performed using Shapiro-Wilk normality test, and the results were not normal in distribution and hemogenity although after transformatted, so non-parametric tests Kruskal-Wallis, were used, followed by Mann-Whitney tests. Result ,the administration of Rubus idaeus extract resulted in the highest total cholesterol levels in group K3 and the lowest in group K5. Statistical analysis showed significant differences (p < 0.05) before and after treatment in each group, with Pearson correlation tests demonstrating a very strong relationship between the dosage of Rubus idaeus and total cholesterol levels. Conclusion, the administration of Rubus idaeus extract significantly reduces total cholesterol levels, with the dose of 90 mg/200gBW being the most effective in lowering total cholesterol levels.
Sustained Effect Of Neurocreative Music Therapy On Upper Limb Abilities, Spasticity, Selective Control And Quality Of Life In Cerebral Palsy: A Case Report
Authors: Çarıkcı Sena , Ünlüer Nezehat Özgül , Torun Şükrü
Published: November 2024

Abstract
This case report, presents the sustained effect of Neurocreative Music Therapy (NCMT) which a uniqe music therapy approach on the upper limb in an individual with cerebral palsy (CP). Our case is a 19-year-old individual with hemiparetic CP and she was included in the 8-week NCMT application program. Before the application, a phenomenological interview was conducted in accordance with the principle of the NCMT approach, which prioritizes the needs and pleasures of the individual. Before and immediately after the 8-week NCMT application, the patient's spasticity was assessed with the Modified Ashwort Scale, selective motor control with the Selective Control of the Upper Extremity Scale, upper limb abilities in daily activities with the ABILHAND-Kids, and quality of life with the Pediatric Quality of Life Inventory CP Module 3.0. As a result of the assessments, an individual-specific music therapy program was planned and implemented. The outcome measurements made immediately after the NCMT application were repeated in the 4th and 8th weeks following the end of the application. According to the results of the scales, it was observed that spasticity decreased, selective motor control increased, upper limb abilities improved, and quality of life increased. The obtained improvements were generally maintained in the 4th week following the end of the therapy. It was observed that there was a decrease in the sustainability of the effect in the 8th week following the end of the therapy in other measurement parameters other than quality of life. As a result, we concluded that NCMT is an effective approach in the rehabilitation of individuals with CP and that its effects may be transferred to the post-rehabilitation period.
Modified Pell Matrix Technique for Solving Optimal Control Problems
Authors: Al-saidi Nadia , Hussain Shaymaa , Al-zahed Farah , Shihab Suha
Published: November 2024

The orthogonal polynomial basis functions are used to solve different mathematical problems, especially for optimal control and many other engineering problems, which attract many researchers to work on. In this study, the modified Pell polynomials (MPPs) are presented and their new properties are investigated to be used for solution approximation of optimal control problems. Some formulas for MPPs are derived by matrices. A new exact formula expressing the derivatives of MPPs explicitly of any degree is constructed. The main advantage of the presented formulas is that the new properties of MPPs greatly simplify the original problems and the result will lead to easy calculation of the coefficients of expansion, it also increases the accuracy and reduces the computational time. A new computational method along with the MPPs is proposed to solve one of the optimal control problems. Numerical results are included to demonstrate the validity of this new technique. It shows an important improvement in error approximation when the polynomial degree is increased.
An Analysis of Geographical Indications in Terms of International, Bilateral and Regional Agreements
Authors: Demirarslan Gökhan , Esen Şaban
Published: November 2024

Abstract
A geographical indication (GI) serves as a quality label that identifies and assures a product’s origin for consumers, highlighting its unique features and the link between these characteristics and its geographical source. Registering a GI provides protection for products that have earned a reputation based on their quality, tradition, regionally sourced raw materials, and local attributes. GIs play a dual role: they not only help transmit local culture to future generations and promote economic development within a country, but they also encompass products with substantial profit potential in international trade. Items such as cheeses, processed animal products, and naturally grown goods (e.g., hazelnuts, grapes, figs) are commonly traded internationally under GI protections. This study aims to analyze international, bilateral, and regional agreements related to GIs, specifically those covering appellations of origin. The analysis includes the 1883 Paris Convention, the 1891 Madrid Convention, the 1958 Lisbon Agreement, and more recent agreements on trade-related intellectual property rights under the World Trade Organization (WTO), as well as bilateral and regional agreements on GIs among countries. Although these agreements address international disputes and trade matters concerning GI products, findings indicate that they can also lead to various challenges between countries regarding the protection and trade of these products.

Keywords: Agricultural Trade, Geographical Indication, TRIPS, International Trade Agreements, WTO, Intellectual Property
JEL Classification: F13, F15, O34, Q17
CUMHURBAŞKANLIĞI KARARNAMELERİNİN NORMLAR HİYERARŞİSİNDEKİ STATÜSÜ ÜZERİNE
Authors: Görücü Veysel
Published: November 2024

16 Nisan 2017’de yapılan halk oylaması ile getirilen en önemli hukuksal araçlardan biri Cumhurbaşkanlığı Kararnamesidir. Cumhurbaşkanlığı Kararnameleri ile Anayasa değişikliği kapsamında yeni hükümet sistemi ile yapılan değişikliklerle en çok öne çıkanlardan biri Cumhurbaşkanına verilen bir yetki olarak TBMM’den bir yetki kanununa dayanmaksızın kararname çıkarılabilmesidir. Kararname çıkarma yetkisi ise genel, soyut ve bir kez kullanmakla etkisi tükenmeyen norm koyma gücünü anlatmaktadır. 16 Nisan 2017’de yapılan değişiklik öncesinde yani Parlamenter hükümet siteminde, kuvvetler ayrılığının bir zorunluluğu olarak norm koyma yetkisi TBMM’ye aittir. Ancak 16 Nisan 2017’de yapılan değişiklik sonrasında Cumhurbaşkanına verilen Cumhurbaşkanlığı Kararnamesi çıkarma yetkisi bu hususa ayrıksı bir düzenleme getirmektedir.
Çalışmada yeni anayasal düzen içerisinde ve hukuki rejim çerçevesinde yürütmenin düzenleyici işlemleri olarak nitelenen Cumhurbaşkanlığı Kararnameleri, diğer düzenleyici işlemler ile karşılaştırmalı olarak, yeni düzenleme sınırları gözetilerek irdelenmiştir. Cumhurbaşkanlığı Kararnameleri hem olağan dönem hem de olağan üstü dönem olmak üzere iki farklı hukuki rejimde Anayasa Mahkemesi kararları ışığında tartışılarak normlar hiyerarşisindeki statüleri doktrindeki karşılaştırmalı görüşler etrafında ele alınmaya çalışılmıştır. Özellikle Cumhurbaşkanlığı hükümet sistemi modeli içinde normun irdelenmesi yeni sistemin işlevselliği açısından da önem arz etmektedir.
Automatic Financial Report Using Accounting Software Based on Artificial Intelligence
Authors: Pandey Shinki Katyayani , Rana Naveen Singh
Published: November 2024

Objective: The application of artificial intelligence (AI) in accounting is not an exception to the way AI is becoming a disruptive force in many industries. In addition to offering accountants the chance to increase productivity, accuracy, and decision assistance, this conceptual paper examines the role of AI in accounting for financial reporting, auditing, and financial decision-making. AI plays a significant role in accounting through data analytics, algorithms, automation, etc., but it also presents certain difficulties.
 
Method: The study employed a cross-sectional survey research methodology with a standardized questionnaire to collect primary data. To analyse the collected data, both descriptive and inferential statistics were applied.
 
Result: The study employed a cross-sectional survey research methodology with a standardised questionnaire to collect primary data. To analyse the collected data, both descriptive and inferential statistics were applied.
 
Conclusion: According to the study's findings, accounting software efficiently gathers and analyses data and information to generate superior company reports. According to the study, accounting software should be easier to use because it gives businesses a simpler way to handle and process financial reporting processes.
Analysis of Environmental, Social, Governance on Tax Avoidance in Companies Listed on the Indonesia Stock Exchange (IDX)
Authors:   Sriwijaya University, Indonesia, . Yusnidar , Chairunnisa Widya Zahra ,   Sriwijaya University, Indonesia, Fuadah Luk Luk ,   Sriwijaya University, Indonesia
Published: November 2024

Every business actor has different business characteristics, so that each company implements a different strategy. Business characteristics describe the industry in which business actors operate, based on the type of business carried out and the main function of each member in the company or business group. In the context of Environmental, Social, and Governance (ESG), determining business characteristics is done through functional analysis. Along with the development of the globalization era, international trade has a significant impact on the economy of a region, and can even affect the economy of a country. This research uses a qualitative method with a literature study approach and literature study, with the aim of analyzing the influence of ESG on tax avoidance. The data collected are scientific articles and international journals. The results show that companies that implement ESG have a higher level of tax avoidance compared to companies that do not implement ESG.
Conexiones 3.0: música, educación física, matemáticas y redes sociales en la sinergia creativa interdisciplinaria del siglo XXI
Authors: Sánchez Parra Maria José , Fernández Cézar Raquel , Martínez-Martinez Jesús
Published: November 2024

Las Redes Sociales son una parte fundamental de la sociedad actual. Son fuente de conocimiento que nutren a la enseñanza formal, permitiendo encontrar recursos que poder utilizar y crear en el aula. El propósito de este trabajo es mostrar el alcance que el uso de videos educativos interdisciplinares en las áreas de Música, Educación Física y Matemáticas, tienen entre los usuarios de una red social en particular. La muestra está compuesta por 30 videos publicados en el mismo período temporal en un perfil de Instagram, 15 de los cuales tienen un carácter educativo e interdisciplinario, y se han comparado con otros 15 videos de carácter no educativo, lo cual ha constituido la variable independiente. Las variables dependientes han sido los datos que nos proporciona la red social Instagram, tales como duración, número de visualizaciones, número de likes y horas de reproducción. Los resultados sugieren como los videos de carácter educativo e interdisciplinar tienen mayor número de visualizaciones, likes y horas de reproducción que los que no tienen ese carácter en el mismo perfil personal, existiendo diferencias significativas. Este trabajo ejemplifica la relevancia que adquiere el trabajo interdisciplinar y las Redes Sociales.
Article RETRACTED due to manipulation by the authors Assessing the Validity, reliability, and relevance of the "Kemp-Vincent Rally Test" for evaluating basic tennis skills in FIK UNY students
Authors: Ngatman Ngatman , Setyawan Hendra , Amajida Abiyyu , Gontara Satria Yudi , Pavlovic Ratko
Published: November 2024

This study aims to assess the validity, reliability, and relevance of the Kemp-Vincent Rally Test as an instrument to evaluate basic tennis skills among students in FIK UNY. The design of this research was quantitative descriptive with a survey method. The population in this research was all students at the Faculty of Sports Science UNY. Then, the samples were chosen from students of four study programs at the faculty. These students had taken tennis courses and could play tennis. They were chosen using a purposive sampling technique, and 34 students were selected, consisting of 22 men and 12 women. The data were collected using tests and measurements. The validity test was carried out by correlating the best results of the test-retest. The results of the ½ competition match were then analyzed using the Spearman Rank Correlation formula through the SPSS for Windows Version 10.0 Program. After that, the reliability was assessed using the same correlation formula, while the relevance was tested using the T-Score formula. The results indicated that the validity test of the Kemp-Vincent Rally test showed a rho value of - 0.782 for male students and -0.822 for female students. The reliability test showed a rho value of 0.981 for male students and 0.944 for female students. In the relevance test, the Kemp-Vincent Rally test for male students was categorized as very relevant (18.18%), relevant (27.27%), and quite relevant (27.27%). Only one-third of the results were classified as less relevant (18.18%) and very less relevant (9.10%). Meanwhile, the relevance test for female students was categorized as very relevant (0.00%), relevant (16.67%), quite relevant (50.00%), less relevant (16.67%), and very less relevant (16.67%). Based on these results, it can be concluded that the Kemp-Vincent Rally Test has adequate validity and reliability and is still relevant if used as an assessment instrument to assess the basic technical tennis skills of FIK UNY students.
Transcription factor AP-4 reactivates telomerase reverse transcriptase independently of genome alteration in non-HBV associated hepatocellular carcinoma
Authors: Lim Huiju , Wu Trevor Kwan-Hung , Suarez Eliana Mary Senires , Yu Tiffany Ching-Yun , Lee Joyce Man-Fong , Tsui Yu-Man , Ho Daniel Wai-Hung , Sze Karen Man-Fong , Ng Irene Oi-Lin
Published: November 2024

Recurrent genome alterations have been identified in the telomerase reverse transcriptase (TERT) promoter region, a common occurrence in various types of cancer. In addition to epigenetic alterations at the TERT promoter region, the recruitment of transcription factors to this region, which potentially drives the reactivation of TERT gene transcription in human hepatocellular carcinoma (HCC) remains unknown. In this study, using in-silico DNA binding sequence analysis at the TERT promoter and with confirmation with dual luciferase reporter and chromatin immunoprecipitation assays, we found that Transcription Factor AP-4 (TFAP4) physically interacted with the TERT promoter, driving telomerase reactivation. Furthermore, TFAP4 mRNA is upregulated in human HCCs and positively correlates with TERT mRNA expression, according to TCGA-LIHC database, our in-house clinical samples, and HCC cell lines. Interestingly, the knockdown of TFAP4 only suppressed TERT expression levels and telomere length in HCC cells which are not associated with HBV infection. Additionally, we identified that the CCCTC-binding factor (CTCF) physically interacted with the TFAP4 promoter, leading to induced TFAP4 gene transcription in HCC. Clinically, TFAP4 mRNA expression significantly correlated with TERT mRNA expression in alcohol-related HCCs, but not in HBV-associated HCCs, according to TCGA-LIHC cohort. Consistently, ethanol enhanced both TFAP4 and TERT mRNA expression in non-HBV-associated HCC cells but not HBV-associated HCC cells. In conclusion, our findings demonstrate that TFAP4 directly regulates TERT gene transcription via CTCF in non-HBV-associated HCCs. However, its role in regulating telomerase expression or activity through HBV DNA integration in HBV-associated cells might be limited.
Secure and Scalable AI: Insights into Federated Learning Algorithms and Platforms
Authors: Aishwarya M. , Chandra J. Umesh , Ali M. Farhan , Bharathi M. , Srinivas T. Aditya Sai
Published: November 2024

This paper takes a closer look at the rapidly advancing field of Federated Learning (FL), a decentralized machine learning approach that focuses on preserving data privacy by training models across multiple devices. It highlights key algorithms like Federated Averaging (FedAvg) and its more refined versions Hierarchical Federated Averaging (HierFAVG) and Federated Matched Averaging (FedMA) which improve model aggregation techniques. The discussion extends to both Horizontal and Vertical Federated Learning (HFL and VFL), illustrating how they handle data partitioning and communication differently. Additionally, the paper reviews prominent FL frameworks and simulators, including TensorFlow Federated (TFF), PySyft, Flower, and FedML, emphasizing their roles in facilitating experiments and ensuring scalability. Critical features like data distribution, communication topologies, and security measures in FL simulators are explored. Ultimately, the paper offers a comprehensive overview of FL frameworks, algorithms, and architectures, showcasing their ability to advance distributed AI while tackling the challenges of data diversity and privacy.