bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Repeatability and Heritability Growth Traits on Indigenous Guinea Pigs in Nigeria
Authors: Afodu Osagie
Published: September 2024

This study focused on the genetic parameter (heritability and repeatability) estimates of growth traits of indigenous guinea pig in Nigeria. The repeatability and heritability estimates of live body weight at birth, pre, and post weaning phases of indigenous guinea pig was measured.
A total of 197 indigenous growing guinea pigs, progeny of 6 sires and 18 dams was selected and raised at the Babcock University Animal holding facilities, Ilishan Remo. They were individually housed in separate labelled plastic cages. Data collected for birth weight, pre, and post weaning weight were used to evaluate the descriptive statistic, repeatability and heritability estimate using Restricted maximum likelihood (REML) of SAS software. The mean values of the live body weight revealed a consistent increase from 76.510g (birth weight) and 83.728 – 241.679 g pre-weaning (week 1-7) weight and 265.600 – 330.884 post-weaning (week 8 – 13) weight in female while the male growing guinea pig had 76.510 g (birth weight to 83.677 – 241.679 g (pre-weaning (week 1-7) weight and 265.600 – 330.986 post-weaning (week 8 – 13) weight.
Birth weight recorded a high estimate of repeatability for growing female guinea pig whereas, the anchored week, 4th week of age for pre-weaning phase and 13th week of age for post-weaning phase were lowly repeatable for female and heritable for male; indicating that additional records would be required to adequately characterize the inherent production ability of live body weight for dam and sire at pre and post weaning phases as breeding age progressed.
It is therefore concluded that the low repeatability and heritability estimates recorded showed that collection of additional records and improvement of non-genetic factors influencing the growth traits would improve the accuracy of data for repeatability and heritability of growth trait of indigenous guinea pigs in Nigeria.
The Effects of Colchicine on the Mitotic Behaviour of Selected Indigenous Tomato (Solanum Lycopersicum L.) Accession
Authors: Udofia Ekaete George , Daudu Oladipupo Yusuf , Isong A. E , Odeyemi Funnke , Adeboye S. E. , Adeshina D. A , Osisami O. F. , Joseph R. I.
Published: September 2024

Colchicine is one of the chemical mutagens that are widely used for inducing mutations in plants. This study was carried out to observe the mutagenic effect of colchicine on the chromosomal characteristic of tomato cells. Seeds of selected tomato accession (NG/SA/07/10/002-NorthEast) were treated with five different colchicine concentrations (0.1mM, 0.3mM, 0.5mM, 1.0mM) and 0.0mM as control. The cytological examination revealed that colchicine was found to induce changes in the chromosomal characteristics of tomato cells in the mitotic stage of development. Different types of chromosomal anomalies such as chromosomal clumping, condensation, fragmentation and chromosomal stickiness were observed. Somatic chromosome number were found to be 2n=24 in control cells and 2n=48 in colchicine treated cells indicating polyploidy.
Ciências sociais e Ciências Naturais na formação em Nutrição: discutindo a opinião de estudantes no Brasil e na Espanha
Authors: Fonseca Alexandre Brasil , Frozi Daniela Sanches
Published: September 2024

Nosso interesse neste estudo está em considerar as diferenças nos cursos de Nutrição do Brasil e da Espanha. Ele faz parte de um estudo comparativo, com o objetivo principal de discutir o papel das ciências sociais na formação em Nutrição nestes dois países. A questão analisada considera a importância relativa dada pelos estudantes de nutrição durante toda a sua graduação. Métodos. Foram utilizados métodos quantitativos e qualitativos. Foram aplicados questionários entre 820 estudantes de 17 universidades no Rio de Janeiro (Brasil) e na Catalunha (Espanha), enquanto grupos focais e entrevistas foram realizadas em ambos os países envolvendo alunos de cada ano do curso realizado. Os resultados do questionário foram analisados ​​utilizando a escala de Likert, com as respostas divididos de acordo com as frequências relativas ponderadas. Resultados. Os estudantes brasileiros consideraram mais importante a disciplina de química ao longo de sua formação (p <0,05), enquanto os estudantes de espanhol, enfatizaram a importância das disciplinas sociais, como sociologia e psicologia (p <0,05) em oposição à química e a estatística. Conclusão. Estes resultados fornecem um aparente paradoxo, pois diante das maiores desigualdades socioeconômicas existentes no contexto brasileiro, as questões sociais poderiam ter maior pertinência para o exercício profissional das futuras nutricionistas. Os resultados deste estudo abrem possibilidades para uma maior contextualização nas abordagens dadas às ciências naturais, incluindo o necessário diálogo com questões relacionadas à sociedade e à cultura, bem como a possibilidade de ampliar o foco do ensino sobre o corpo humano ao articular aspectos sociais, econômicos e políticos.
Desnutrição infantil e seus determinantes imediatos, subjacentes e básicos em Moçambique: uma análise temporal de 1997 a 2015
Authors: Culpa Matias , Oliveira e Silva Denise , Paulo de Souza Nathalia , Angela Pessoa Cesse Eduarda
Published: September 2024

Introdução: O déficit de altura para idade (desnutrição Crônica) em crianças menores de 59 meses é um dos problemas de saúde pública que afeta vários países em desenvolvimento, como Moçambique. Objetivo: Descrever à tendência da desnutrição crônica em crianças menores de 59 meses no período de 1997 a 2015 e seus fatores associados. Metodologia: Utilizou-se dados de 7 inquéritos nacionais realizados entre 1997 à 2015. Foi considerada cronicamente desnutrida a criança que se encontrava abaixo de -2 desvios padrão. Para identificar as causas imediatas, subjacentes e básicas foi adotado o modelo conceitual da desnutrição proposto pela UNICEF. Os dados foram agrupados por regiões (norte, centro e sul) e zona de habitação (rural e urbana). O coeficiente de correlação de Spearman foi utilizado para identificar a associação entre as variáveis. Resultados: Desde 1997, a desnutrição tem se mantido como um importante problema de saúde pública em Moçambique. As regiões norte e centro são as que apresentam as mais altas prevalências de desnutrição, baixas condições socioeconômicas e demográficas, quando comparadas com o sul do país. Não foi identificada relação estatística entre as causas imediatas, subjacentes e básicas e a desnutrição na população desse estudo. Conclusão: Apesar da ausência de relação significante, foram encontradas diferenças regionais e por zona de habitação na prevalência de desnutrição crônica, sugerindo que as políticas sociais devem priorizar áreas mais vulneráveis.
“Faltam direitos": percepções sobre a alimentação em uma escola pública estadual, em Salvador, Bahia
Authors: Ferreira Barreto Mércia , Soares de Freitas Maria do Carmo
Published: September 2024

Propõe-se analisar as percepções relativas ao Programa Nacional de Alimentação Escolar (PNAE), especificamente no que se refere às refeições servidas em uma escola pública da cidade de Salvador, Bahia. Trata-se de uma abordagem abrangente da percepção e dos significados acerca desse tema, bem como suas implicações sobre o direito humano à alimentação adequada. Essa análise é realizada por meio das narrativas escritas e orais dos jovens envolvidos. A pesquisa revela condições de alimentação que estão associadas a outras carências sociais e que são contrárias ao direito humano à alimentação. Nesse contexto, reflete-se sobre a necessidade de tomar medidas diante às violações apontadas pelos estudantes.
O que envolve o consumo alimentar e como a pandemia por COVID-19 pode ter influenciado nesse aspecto da vida das pessoas
Authors: Zago Mayla Angelini
Published: September 2024

O ensaio trata da contextualização da refeição. Apresenta as motivações que a envolve, contemplando as dimensões dessa complexa engrenagem; englobando os relacionamentos, convivência, questões financeiras, a saúde, o sabor e outros possíveis. A partir de todos esses conceitos, o ensaio aborda a caracterização das escolhas alimentares que abrangem as experiências ao longo da vida, as influências recebidas para então contextualizar todo esse sistema alimentar pessoal. São apresentados os conceitos da prática e do hábito alimentar para então contemplar o recorte temporal e comunitário visando o entendimento de determinada realidade. Sendo assim, a pandemia por COVID-19 mundialmente experenciada em 2020 e 2021 trouxe a discussão desses “novos” hábitos, se foram inseridos de forma passageira ou duradoura na vida dos indivíduos.
A insegurança alimentar como expressão da questão social
Authors: Campos Francieli do Rocio de
Published: September 2024

A influência dos acontecimentos históricos na condição social da sociedade tem sido responsável por impactar no âmbito alimentar mais enfaticamente durante o período da industrialização. Com isso, esse trabalho tem por objetivo consolidar um arcabouço teórico a partir de fontes bibliográficas de autores que se dedicam a difundir a questão social e suas expressões sociais, assim atrelar a discussão teórica sobre a insegurança alimentar. Pois, as expressões da “questão social” se constituíram em desemprego, desigualdade social e pobreza, que repercutiram na renda que influência na saúde, moradia, trabalho, educação e que estará abarcado no acesso e qualidade alimentar do indivíduo. Tais questões, que o Estado tem por obrigatoriedade garantir ao sujeito, porém com o passar do tempo tem sido negligenciado por ele, e o indivíduo que vive na vulnerabilidade permanece a mercê das políticas públicas.
FUNCTIONAL OUTCOME OF CLOSED INTRAARTICULAR DISPLACED CALCANEAL FRACTURES MANAGED WITH LOCKING PLATE FIXATION
Authors: Singh Rajan , P. A Arvindh , Sharma Shiv Bhagwan , Seth Pallav
Published: September 2024

The treatment of displaced intraarticular calcaneal fractures remains a challenge to orthopaedic
surgeons since long time. Complications associated with conservative treatment i.e. incongruence of the
posterior facet and, incongruence of the calcaneocuboid joint, arthritis, pain, heel widening leads to functional impairment to
patients. Recent advances in this eld of surgery have enabled surgeons to perform open reduction internal xation with locking
plate using extensile lateral approach in a safe, and reliable manner and to get better functional outcome by maintaining
surgical anatomy and preventing complications associated with conservative treatment of displaced intraarticular calcaneal
fractures.
RELAPSE OF NMO NEGATIVE NEUROMYELITIS OPTICA SPECTRUM DISORDER IN A MIDDLE AGED INDIAN FEMALE-A CASE REPORT
Authors: Gaur Ishana
Published: September 2024

Background: Neuromyelitis Optica Spectrum Disorder(NMOSD) is a central nervous system
inammatory disease usually with a relapsing course, that has a particular predilection to cause Optic
Neuritis and Longitudinally extensive Transverse Myelitis (LETM).Approximately 70% of cases are associated with antibodies
to Aquaporin 4 immunoglobulin G(AQ4IG-G). A 45 year old female resented to Civil Hospital Ahmedabad Case presentation:
with complain(s) of bilateral lower limb weakness, sub acute in onset ,progressive in nature, complain of loss of touch and pain
sensation in bilateral lower limbs, urinary incontinence, all since 10 days. She had a history of similar illness 9 year ago and a
history of sudden onset painful loss of vision in left eye consistent with optic neuritis in one year ago. On Neurological
examination, there was loss of sensation below nipples, lower limbs was 0,DeepTendon reex of bilateral lower limbs were
exaggerated, Plantar were upwards bilaterally.Labs: Complete Blood count ,Liver Function Tests, Renal Function Tests all were
within normal range .Serum B12 was within normal range.ANA by Indirect Immuno uorescence was negative.HIV was
negative. On routine CSF examination, protein was 18 mg/dl, cells were 2/hpf.CSF showed no unique Oligoclonal bands.
Serum Aquaporin 4 immunoglobulin G(AQ4IG-G)negative, Myelin Oligodendrocyte Glycoprotein(MOG) antibody negative.
Fundus examination was normal.MRI dorsal spine was suggestive of Longitudionally Extensive Transverse Myelitis(LETM),
from D2-D12 level with diffuse grey and white matter involvement,hyperintense on T2 and STIR. MRI brain was suggestive of
chronic small vessel ischemic changes.Patient was diagnosed Acute Transverse Myelitis due to relapse of AQ4IG-G negative
Neuromyelitis Optica Spectrum Disorder(NMOSD). She was started on high dose methylprednisolone and Plasma Exchange.
The patient improved signicantly after starting the treatment. She was discharged on oral steroids and Azathioprine.
Summary: Relapses in NMOSD tend to be more severe and disabling .The recovery is often incomplete with incremental
disability. It is very important to diagnose this disease early and distinguish it from Multiple Sclerosis (MS)because of a
number of drugs used for MS are ineffective and potentially harmful for NMOSD. Management of NMOSD is directed for
rescue treatment for acute attacks which includes combination of Plasma exchange and steroids and maintenance immune
therapies.
AN OBSERVATIONAL STUDY TO COMPARE INTRAOPERATIVE HEMODYNAMIC STABILITY AND RECOVERY CHARACTERISTICS OF BISPECTRAL INDEX GUIDED AND MINIMUM ALVEOLAR CONCENTRATION GUIDED ANAESTHETIC DEPTH IN LAPAROSCOPIC ABDOMINAL /PELVIC PROCEDURES.
Authors: Shrivastava Neha , Khanna Sangeeta , Das Jyotirmoy , Rani Neha
Published: September 2024

Background and Aims: Monitoring the depth of anesthesia using Minimum Alveolar Concentration (MAC) or Bispectral Index (BIS) allows for
individualized anesthesia management by adjusting drug administration based on the patient's level of arousal. This study aims to compare the
effects of these two methods on hemodynamic stability and recovery outcomes during laparoscopic surgeries. Sixty patients undergoing Methods:
elective laparoscopic surgeries under general anesthesia were enrolled in this double-blind observational prospective randomized study and
allocated into two groups. Hemodynamic parameters and recovery characteristics were compared. The depth of anesthesia was monitored using
BIS in group B (n = 30) and using MAC in group M (n = 30). There was no signicant difference in hea Results: rt rate at all time points except at end
of port placement (p=0.03) and at 10 minutes after extubation (p=0.005) HR was higher in group M then group B. There was no signicant
difference in mean arterial pressure at any time point except it was signicantly lower in group M than group B at 15 minutes, 30 minutes and 60
minutes after port placement. MAC values were signicantly lower in group B compared to group M. The BIS values were signicantly lower in
the group M compared with the group B. Time to eye-opening, time to extubation, discharge from PACU, sevourane consumption (4.40±2.06
minutes), (5.85±1.79 minutes), (1.68±0.27 hours), (15.83±7.97 ml) respectively in group B was signicantly lower than that in group M for same
parameters respectively (6.33±2.73 minutes), (8.10±2.52 minutes), (1.98±0.15 hours), (20.97±8.51 ml). Titration of inhalational Conclusions:
anaesthetic agent to maintain a BIS value in the range of 40- 60 during general anesthesia for laparoscopic abdominal/pelvic surgeries provide
better hemodynamic stability and reduction in the consumption of volatile anesthetic agent along with rapid emergence and shorter stay in PACU.
Mettersi al punto giusto: Franco Villoresi ‘maestro’ dell’atelier di pittura dell’Ospedale neuropsichiatrico di Arezzo | Franco Villoresi
Authors: Quattrocchi Luca
Published: September 2024

This essay deals with the activity of painter Franco Villoresi (1920-1975), from his beginnings in Rome in the late 1940s to his involvement as a "master" in the painting atelier for the patients of the Arezzo Neuropsychiatric Hospital, opened in 1958 by his friend Furio Martini, vice-director of the institute.
Villoresi’s first works drew on Mario Mafai’s paintings, his master. Villoresi achieved expressive autonomy in the 1950s in the framework of an alienating realism, with views of suburbs and train stations in which faceless human silhouettes wander as if lost. This phase was followed by the period of the “Grandi personaggi”, a satire of the respectability and conformism of wealthy society. During his teaching in the Aretine hospital atelier (from 1958 to 1961), in contact with a sorrowful humanity unadulterated by conventions and superstructures, Villoresi elaborated the theme of the mask, which was to become the constant emblem of his painting to come in all its moral and existential implications.
Impact of Dexamethasone on Lignocaine and Ropivacaine Mixture for supraclavicular Brachial Plexus Block: A Prospective, Randomized, Double Blind Trial
Authors: Ahmad Riyaz , Ali Omais
Published: September 2024

Supraclavicular brachial plexus block is a common regional anesthesia technique used for upper extremity orthopedic surgeries. The addition of adjuvants to local anesthetics can prolong the duration of analgesia and improve the quality of the block. This prospective, randomized, double-blind study aimed to investigate the impact of dexamethasone on the efficacy of a lignocaine and ropivacaine mixture for ultrasound guided supraclavicular block. A total of 80 patients scheduled for major forearm orthopedic surgery were randomly assigned to receive either a mixture of lignocaine 2% and ropivacaine 0.5% (control group) Group A or the same local anesthetic mixture with the addition of dexamethasone 8 mg (dexamethasone group) Group B. The primary outcome was the duration of analgesia, defined as the time from block placement to the first request for rescue analgesia. Secondary outcomes included the onset time of sensory and motor block, the quality of the block, and the incidence of adverse events. The results showed that the addition of dexamethasone significantly prolonged the duration of analgesia compared to the local anesthetic mixture alone (135 ± 10 min vs. 170 ± 15 min, respectively, p < 0.001). Addition of dexamethasone to mixture of lidocaine and ropivacaine in supraclavicular block results in prolonged duration of sensory and motor block and also improves quality of analgesia without affecting its onset.
Assessment of the Differences in Juvenile Crime Based on Family set-up among Secondary School Students in Kisii County, Kenya
Authors: Okenyuri Nyarangi Esther , Otieno Rose , Onderi Peter
Published: September 2024

Juvenile crime is a huge concern across the world today. Young individuals engage in antisocial behaviors such as theft, robbery, rape, drug and substance misuse, drug trafficking, disdain for authority, and even murder. The purpose of the study was to assess the differences in juvenile crime according to family set-up among secondary school students in Kisii County, Kenya. A descriptive survey research approach was adopted. The study's target population comprised 6,357 students from selected secondary schools. The sample size included 610 students, 9 school officials (principals, deputy principals, and teacher counsellors, one from each school), and 9 parents. The sample only included pupils from grades two and three. Both probability and non-probability sampling approaches were utilized. The schools were chosen using the convenience sampling approach. In contrast, simple random sampling was used to pick student respondents from schools A and B, and purposive selection was used to select student respondents from school C and all school administrators. The parents were also picked using convenience sampling. Data was gathered through student and teacher surveys, principal interview schedules, and parent focus groups. Data was analyzed using correlation analysis with the Statistical Package for Social Sciences (SPSS) version 25. The findings revealed that upper-class adolescents were more delinquent than lower-class adolescents and that the media impacts juvenile crime. The research advised that media be used appropriately to minimize crime and that upper-class parents limit the digital gadgets available to their children.
Comparative study of serum zinc levels in stable asthmatic versus non-asthmatic children
Authors: Obijiaku Ifesinachi , Amadi Ogechukwu , Eze Joy , Eke Christopher , Uleanya Nwachinemere , Ndu Ikenna , Ikefuna Anthony
Published: September 2024

Objective: Zinc is an essential trace element that plays a critical role in various physiological processes, including immune function and antioxidant defense. Serum zinc levels are often used as a marker to assess nutritional status and potential deficiencies. This study aims to compare serum zinc levels between stable asthmatic children and non-asthmatic controls at ESUT Teaching Hospital, Parklane Enugu, to understand whether asthmatic children have different zinc status compared to their non-asthmatic counterparts.
Materials and Methods: A comparative cross-sectional study was conducted involving 85 asthmatic and 85 non-asthmatic children aged 5–11 years. Serum zinc levels were assessed using a Flame Atomic Absorption Spectrophotometer (FAAS). Data were analyzed using SPSS version 20.
Results: The median serum zinc levels were 11.95 µmol/L in asthmatic children and 8.81 µmol/L in non-asthmatic children (p < 0.001). Nutritional status and socio-economic class did not significantly affect serum zinc levels.
Conclusion: Stable asthmatic children have higher median serum zinc levels compared to non-asthmatic children. There was no significant relationship between serum zinc levels and socio-economic or nutritional status in the asthmatic group. Blind zinc supplementation in asthmatic children should be approached with caution.
Manejo dos Pacientes com Osteoporose
Authors: Barbosa Silva Pedro Augusto , Barroso da Silva Mateus de Grise , Catuladeira Nascimento Rafael Maciel , Oliveira Neves Ana Clara , Sanches de Sousa Ana Beatriz , Calil Rachel Penchel , Santana Vitória Leite , Lurchevicz Ágatha Beatriz , Moura Gonçalves Ana Karollina de , Cupolillo Arthur Vieira , Santos Miranda Danielle Oliveira
Published: September 2024

Introdução: A osteoporose é uma doença sistêmica que apresenta deterioração da microarquitetura do tecido ósseo e redução da massa óssea, acarretando na suscetibilidade à fratura e elevação da fragilidade óssea. Essa condição pode ser dividida em primária e secundária. Os fatores de risco são sexo feminino, pessoas caucasianas e asiáticas, deficiencia vitamina D, calcio, pouca exposição solar, ingesta excessiva fosforo ou sal, uso cronico de glicocorticoide, anticonvulsivantes, quimioterapia ou sedativos, além de menopausa tardia e deficiencia de estrogenio no periodo anterior a menopausa. As manifestações clínicas vão desde quadros assintomáticos até fraturas osteoporóticas. A identificação da doença é importante para o tratamento e prevenção dessa condição. Objetivo: analisar a importância do manejo dos pacientes com osteoporose. Método: Trata-se de uma revisão integrativa dos últimos 3 anos, do período de 2021 a 2024, utilizando as bases de dados da Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Medline com os descritores: "osteoporose" "tratamento" "manejo" "conduta". Foram encontrados 35 artigos, sendo eles submetidos aos critérios de seleção. Resultados e Discussão: Foram selecionados 4 artigos. Nas fraturas de fragilidade pélvica do tipo I e II, normalmente, se adota tratamento conservador, já nas do tipo III e IV o tratamento cirurgico. O diagnóstico e tratamento dessa condição é importante para prevenir uma possível fratura. Uma medida importante é a prevenção de quedas que inclui a suspensão de medicamentos que podem aumentar esse risco. Além disso, é importante o tratamento da propria osteoporose com medidas não farmacológicas, que inclui mudanças na alimentação e prática de atividade física, além do uso de fármacos, como os antirreabsortivos ou anabólicos para reduzir essa fragilidade óssea e risco de fratura e complicações. O tratamento cirúrgico pode ser utilizado a depender das particularidades da lesão e do paciente. Conclusão: Nessa perspectiva, o tratamento é importante para melhorar a qualidade de vida do paciente e prevenir possíveis fraturas.
Ampla abordagem sobre a Síndrome dos Ovários Policísticos
Authors: Rosa de Araújo Ana Luiza , Rodrigues Lassala Juliana , Machado Torquato Larissa , Camila Torres e Silva Paula , Barbosa de Freitas Jaylane , Tereza Lira Dias Maria , Cozzolino Ferreira Raffaelli Thereza , Gulminetti Mororo Bruna , Ferreira de Azevedo Adriane , Dos Santos Kishishita Castro Kaline
Published: September 2024

Este artigo explora a Síndrome dos Ovários Policísticos (SOP), uma condição prevalente entre mulheres em idade reprodutiva, marcada por uma ampla gama de sintomas. A variabilidade na prevalência da SOP, influenciada por fatores genéticos, ambientais e socioeconômicos, sublinha a necessidade de diagnósticos precisos e tratamentos personalizados. A revisão sistemática realizada visa elucidar os mecanismos fisiopatológicos da SOP, identificar fatores de risco e discutir abordagens de manejo eficazes, com uma coleta extensiva de dados de fontes como PubMed e SciELO, focando em publicações que tratem das manifestações e tratamentos da SOP.
Os resultados apontam para o desequilíbrio hormonal, especialmente o aumento de androgênios e a resistência à insulina, como centrais na patogênese da SOP. Essas disfunções contribuem para sintomas como irregularidades menstruais, infertilidade e obesidade, impactando significativamente a saúde mental e a qualidade de vida. A complexidade dos desafios enfrentados por mulheres com SOP também inclui um risco elevado de comorbidades metabólicas e reprodutivas. A discussão enfatiza a necessidade de uma estratégia de tratamento multidisciplinar e personalizada, que considere fatores genéticos e socioeconômicos das pacientes. O manejo deve envolver não só intervenções hormonais, mas também mudanças no estilo de vida, como dieta e exercícios físicos, para responder eficazmente às necessidades das mulheres com SOP. Conclui-se que a SOP exige um entendimento profundo de seus mecanismos e uma abordagem cooperativa no desenvolvimento de tratamentos, com pesquisas contínuas e práticas baseadas em evidências para melhorar a saúde e qualidade de vida das pacientes.
Antibody-based biological antiviral drugs for the prevention and treatment of acute respiratory viral infections in immunocompromised patients: focus on safety
Authors: Geppe Natalya , Zaplatnikov Andrey , Kondyurina Elena , Blokhin Boris , Revyakina Vera , Abdrakhmanova Sagira , Romanova Oksana , Kolosova Natalia
Published: September 2024

The safety of drug therapy is of particular importance for immunocompromised patients. This aspect acquires high importance in the context of choosing tactics for the prevention and treatment of acute respiratory viral infections.
The review presents data on the features of the antiviral immune response and common cold/influenza in patients with a burdened allergic history and a brief overview of the results of clinical studies on the effectiveness and safety of innovative biological antiviral drugs based on antibodies to biological targets – Ergoferon, Anaferon for children and Anaferon. The drugs have a targeted effect on the immune system in accordance with their pharmacological targets, have a significant evidence base, including a meta-analysis of clinical trials for each drug according to the indication "acute respiratory viral infections/influenza", as well as individual studies, including double-blind placebo-controlled randomized, with this pathology in immunocompromised patients.
The article also includes the results of a generalized safety analysis of the use of the above drugs for the prevention and treatment of acute respiratory viral infections/influenza in patients with concomitant allergic and autoimmune pathology.
The results of the conducted studies, meta-analyses and generalized statistical analysis of data on the use of the drugs Anaferon for children, Anaferon, Ergoferon for the prevention and treatment of acute respiratory viral infections/ influenza indicate proven efficacy and a favorable safety profile and allow us to recommend drugs for wide use with preventive and therapeutic purposes in accordance with indications, including patients with allergic and autoimmune pathology.
Marketing Strategy Of Tomatoes (Solanum Lycopersicum Mill) Using Soar And Qspm Methods In The Argoayuningtani Farmers Group, Senden Village, Selo District Boyolali District
Authors: Latif Mahmudi Wildana , Prasetyo Agung , Suswadi  , Ridyo Arum Mutiarra , Prasetyowati Kusriani
Published: September 2024

This research aims to: (1) determine the internal factors that are the strengths and aspirations of tomatoes marketing in Senden Village, Selo District, Boyolali Regency. (2) knowing the external factors that become opportunities and results in tomato marketing in Senden Village, Selo District, Boyolali Regency. (3) knowing the marketing strategy for tomatoes in Senden Village, Selo District, Boyolali Regency. The method used in this research is quantitative descriptive. The selection of research locations was carried out purposively, namely Senden Village, Selo District, Boyolali Regency. Sampling with key informants. The types of data used are primary data and secondary data. Data collection techniques using observation, interviews and recording. The data analysis used is the SI and AI matrix, IE matrix and SOAR (Strength, Opportunity, Aspiration, Result) analysis. The results of the analysis from this research are that the SI matrix has a score of 2.28 and the AI matrix has a score of 2.31. The IE matrix analysis is in cell I, meaning this strategy is to grow and build (Hold and Maintain) with an intensive strategy consisting of market penetration, development and product development that focuses on existing tomatoes. The results of the SOAR analysis show five alternative strategies.
INTEGRATED SOCIO-ECONOMIC DEVELOPMENT OF THE REGION WITH AN EMPHASIS ON SOCIAL POLICY
Authors:   South Ossetian State University named after A. Tibilov, Gagloeva Evelina N. , Gavrilova Olga Y. ,   Krasnoyarsk State Agrarian University, Bischekova Fatima R. ,   Kabardino-Balkarian State University named after Kh. M. Berbekov, Olisaev Aslan S. ,   North Caucasus Mining and Metallurgical Institute (State Technological University)
Published: September 2024

The social policy of the region, as a rule, plays a very important role in the development of the region, as it is a guarantor of the well-being of people. The article analyzes the issues of the socio-economic situation of the Republic of North Ossetia–Alania for 2023 to the level of 2022. Unresolved problems are identified. The most important tasks have been formed to reach a new level of effective development of the region.
FORMATION OF INITIATIVES TO STIMULATE DEVELOPMENT INNOVATION SYSTEM OF THE REGION
Authors:   Kazan Cooperative Institute (Branch of the Autonomous Non-Commercial Educational Organization of Higher Education of the Central Union of the Russian Federation “Russian University of Cooperation”), Zhilina Nadezhda N. , Ignatiev Vladimir G. ,   Kazan Institute of Chemical Technology
Published: September 2024

At the current stage of economic development, investment activity cannot do without support from the state, since scientific developments and their production require huge investments. Only the state is capable of providing significant financial support in the implementation and development of the innovation process. State investment policy consists of measures that create favorable conditions for the effective development of innovation activities and living conditions of the population. The need for government intervention in innovation processes is determined not only by the long research and production cycle, high costs, but also by the uncertainty of the final result. Today, there are factors that hinder the development of innovation, one of which is insufficient motivation on the part of the state and companies in the development of innovation. We have examined the main measures of government influence on the innovative development of the modern Russian economy, contributing to the development of the innovation process, increasing the competitiveness of products, and generating additional income. Methods of state support for innovation activities in the Russian Federation have been studied. Only close interaction between the state and private entrepreneurship makes it possible to implement an innovation policy strategy.
DEVELOPMENT OF SECONDARY VOCATIONAL EDUCATION (USING THE EXAMPLE OF THE KHABAROVSK KRAI)
Authors:   Pacific National University, Kushnerova Oksana N.
Published: September 2024

The vocational training system has undergone many transformations over more than 300 years. The most difficult period occurred in the late 1990s and early 2000s, when secondary vocational education seemed less attractive to school graduates. The shortsightedness of government officials in the educational sphere of that period led to the fact that most sectors of the economy are faced with an acute shortage of skilled workers and mid-level workers at the present time. For the accelerated development of the economy of the Far East, specialists with new working competencies are needed, and therefore quite high demands are placed on their professional training. The article analyzes the current situation in the market for blue-collar jobs in the Khabarovsk Territory and examines the main directions and prospects for the development of secondary vocational education in the Far Eastern region.
THE COMPANY’S INTERACTION WITH STAKEHOLDERS IN THE PROCESS OF STRATEGIC DEVELOPMENT
Authors:   FSBEI HE «Russian State University for the Humanities», Moscow, Russia, Spilnichenko Vladimir K. , Boldyreva Saglar B. ,   Kalmyk State University named by B. B. Gorodovikov, Elista city, Russian Federation
Published: September 2024

The purpose of the study is to identify and typologize the relationships between an enterprise and its key stakeholders in the context of business process implementation, aimed at creating a classification system and understanding the role of each type of communication to ensure effective strategic development of the enterprise. The strategic development of the enterprise requires the identification of a range of important stakeholders, since the reliability and stability of interaction with them contributes to ensuring the effectiveness and optimization of business processes of the enterprise. The article identifies and characterizes the types of relationships between the enterprise and stakeholders in accordance with their participation in the implementation of business processes of the enterprise. The implementation of an enterprise’s business processes requires clarity and consistency, which depends on the efficiency of providing them with certain types of resources and, accordingly, proper relationships with stakeholders are a guarantee of their implementation. Therefore, the issue of typologizing the relationships of an enterprise with stakeholders is relevant. The types of relationships between the enterprise and stakeholders are highlighted in accordance with their participation in the implementation of business processes of the enterprise. The parameters of the allocation of stakeholders in accordance with the specified types of their relationships with enterprises are proposed. The expected results of the study are aimed at determining specific parameters for identifying stakeholders in accordance with the specified types of relationships, and are also focused on establishing appropriate relationships with each type of stakeholders as a guarantee of efficiency and successful implementation of business processes, which contributes to the stability and reliability of the company’s interaction with its environment.
ESG-FINANCING AS A KEY FACTOR OF SUSTAINABLE DEVELOPMENT IN RUSSIA
Authors:   Kazan (Volga Region) Federal University, Kazan, Russia, Kondrateva Ekaterina V. , Ignatjeva Oksana A. ,   Kazan (Volga Region) Federal University, Kazan, Russia, Rocheva Olga A. ,   Kazan Cooperative Institute (branch) of Russian University of Cooperation, Kazan, Russia, Zaripova Rimma S. ,   Kazan State Energy University, Kazan, Russia
Published: September 2024

In the period of constantly changing “rules of the game” in all spheres of life it is necessary to pay great attention to social aspects, that is why ESG implementation is an integral part of doing business. ESG-financing is the key to solving many problems of companies. For successful and long-term activity of any company (corporation) first of all the support of the state and banking sector is necessary. These support measures can and do have a significant impact on the rating of domestic companies not only in the domestic market, but also to enter the global arena. This article considers ESG-principles, measures contributing to the effective implementation of ESG-principles, stages of “greening” the banking sector, analyzes ESG-financing of Otkritie Bank and Sberbank.
BASKETBALL AS A MEANS OF DEVELOPING THE PHYSICAL QUALITIES OF STUDENTS OF A TECHNICAL
Authors:   Kazan Federal University, Kazan, Russia, Abzalov Nail I. , Ilyushin Oleg V. ,   Kazan (Volga Region) Federal University, Kazan, Russia; Kazan State Power Engineering University, Kazan, Russia, Ilyushina Tatyana P. ,   GKUZ “Republican Specialized Children’s Home”, Kazan, Russia, Ilyushina Polina O. ,   SSC «IT Lyceum», Kazan (Volga Region) Federal University, Kazan, Russia
Published: September 2024

This article examines the role of basketball in improving the physical and motor skills of students at technical universities. The purpose of the study is to popularize basketball as a means of developing the physical qualities of students, as well as to compare it with other sports and analyze the problems of its development among students. Methods of literature analysis and statistical analysis of the obtained data are used, and the training program is described. The article discusses the problem of limited access to basketball for students without professional experience and proposes an initiative to expand the availability of this sport through free classes and the creation of student amateur teams. The issue of the influence of basketball on the general physical condition of students is considered.
Penerapan Pijit Oksitosin Dalam peningkatan Produksi ASI
Authors: Futriani Elfira Sri , Chotimah Chusnul
Published: September 2024

Rendahnya cakupan ASI eksklusif dikarenakan kurangnya pengetahuan ibu, faktor sosial budaya, kurangnya informasi tentang ASI eksklusif dan konseling laktasi dari tenaga kesehatan serta kuatnya promosi susu formula. Pijatan oksitosin berfungsi untuk meningkatkan hormon oksitosin yang dapat meningkatkan kenyamanan ibu menyusui, sehingga ASI pun otomatis keluar. Tujuan penelitian ini membuktikan pijat oksitosin dalam meningkatkan kenyamanan dan produksi ASI. Desain penelitian yang digunakan adalah quasi eksperimen dengan pendekatan pre-post test design with control group. Sampling yang digunakan adalah consecutive sampling, sebanyak 18 Responden, dibagi 2 kelompok. Kenyamanan diukur dengan GCQ (General Comfort Questionarre), Produksi ASI diukur dengan Weighing Test. Data diukur sebelum dan sesudah dilakukannya tindakan, kemudian dianalisis dengan ANOVA dengan α ≤ 0,05. Hasil analisis untuk kenyamanan didapatkan nilai p=0,035 yang berarti ada perbedaan kenyamanan yang signifikan antara pijat Oksitosin dan Kelompok kontrol. Hasil pengukuran produksi ASI didapatkan nilai p=0,013 yang berarti ada perbedaan produksi ASI yang signifikan antara pijat oksitosin dan Kelompok kontrol. Pijat oksitosin dapat meningkatkan kenyamanan dan produksi ASI pada ibu postpartum. Untuk itu perlu digunakan sebagai intervensi alternatif dalam melakukan perawatan pada ibu postpartum terutama terkait masalah laktasi, dan perawat perlu mengajarkan teknik pijat oksitosin ini kepada pasien dan keluarga, supaya keluarga lebih berperan serta dalam mendukung program ASI Eksklusif.
Hubungan Tingkat Pengetahuan Keluarga Tentang Penyakit Stroke dengan Penanganan Pre Hospital
Authors: Aminah Siti , Sri Futriani Elfira
Published: September 2024

Pola hidup masyarakat Indonesia yang bergeser ke arah gaya hidup yang serba instant dan cepat saji, mempengaruhi terhadap kesehatan bagi setiap orang, ditambah dengan faktor seperti kurang aktivitas fisik, konsumsi makanan yang cepat saji dan dampak dari stress, yang dapat memicu faktor terjadinya serangan stroke yang bisa berujung pada kematian. Penelitian ini untuk mengetahui pengaruh edukasi kesehatan tentang penanganan kegawatdaruratan stroke pre hospital terhadap pengetahuan keluarga. Jenis Penelitian ini adalah pre experimental design dengan menggunakan desain one-group pre test- post test design. Populasi dalam penelitian ini berjumlah 120 anggota keluarga dan ditentukan 30 sampel menggunakan metode purposive sampling. Responden diberi perlakuan berupa edukasi kesehatan tentang penanganan kegawatdaruratan stroke pre hospital. Analisis data disajikan dalam bentuk tabel dan diuji dengan Wilcoxon Signed Rank Test. Hasil uji statistik Wilcoxon Signed Rank Test menunjukkan pengetahuan keluarga sebelum dan sesudah diberikan treatment dengan pValue=0,000 (α=0,05). Edukasi kesehatan berpengaruh secarah bermakna terhadap pengetahuan keluarga tentang penanganan kegawatdaruratan stroke pre hospital. Saran dari penelitian ini, tenaga kesehatan dapat memberikan promosi kesehatan berupa pemberian edukasi kesehatan ataupun pelatihan yang berkesinambungan agar menambah wawasan kepada keluarga tentang penaganan kegawatdaruratan.
EXAMINATION OF RIVER INFRASTRUCTURE CONSTRUCTION PROJECTS
Authors: Прокопенко Анастасия Александровна
Published: September 2024

Речная инфраструктура играет важную роль в обеспечении устойчивого развития региона и страны в целом. В статье рассматривается процесс экспертизы проектов строительства речной инфраструктуры в России. Статья подчеркивает необходимость комплексного подхода для устойчивого и эффективного развития речной инфраструктуры.

River infrastructure plays an important role in ensuring the sustainable development of the region and the country as a whole. The article discusses the process of examination of river infrastructure construction projects in Russia. The article emphasizes the need for an integrated approach for sustainable and efficient development of river infrastructure.
METHODS FOR DETERMINING THE EFFECTIVENESS OF ACCESSORY COMMUNICATION
Authors: Трухан Роман Петрович
Published: September 2024

В работе рассказывается о проблемах установления методов определения эффективности акцессорной связи, как правового средства. Сделан вывод о сложности такого исследования ввиду смешения категорий «результативность» и «эффективность» акцессорной связи, недостаточности эмпирического материала, имеющего количественные оценки, а также отсутствие комплексного подхода в использовании методов и методик.

The work describes the problems of establishing methods for determining the effectiveness of accessory communication as a legal means. A conclusion is made about the complexity of such research due to the confusion of the categories “effectiveness” and “efficiency” of accessory communication, the lack of empirical material with quantitative estimates, as well as the lack of an integrated approach to the use of methods and techniques.
ПРАВОВОЙ РЕЖИМ ГЕОГРАФИЧЕСКОГО УКАЗАНИЯ И НАИМЕНОВАНИЯ МЕСТА ПРОИСХОЖДЕНИЯ ТОВАРОВ
Authors: Киселева Надежда Анатольевна
Published: September 2024

Разнообразие рынка материальных благ достаточно велико и без возможности различать товары и услуги даже в рамках какой-либо одной категории, удовлетворить потребности рядовых граждан, а производителю товаров обеспечить стабильный доход от реализации товаров и услуг, чрезвычайно затруднительно. Вследствие чего такие правовые инструменты как средства индивидуализации товаров, работ и услуг играют важную роль в сфере регулирования оборота, реализации продукции и формировании стабильных рыночных отношений.
МОДЕЛЬ ИССЛЕДОВАНИЯ ИНТЕЛЛЕКТУАЛЬНОЙ ГОТОВНОСТИ К ОБУЧЕНИЮ В ШКОЛЕ У ДЕТЕЙ СТАРШЕГО ДОШКОЛЬНОГО ВОЗРАСТА
Authors: Долгова Валентина Ивановна , Кондратьева Ольга Александровна , Федотова Ангелина Сергеевна
Published: September 2024

Для обсуждения на конференции предлагаем модель формирования интеллектуальной готовности к обучению в школе у детей старшего дошкольного возраста, генеральная цель которой - теоретически обосновать и экспериментально проверить эффективность реализуемой программы формирования интеллектуальной готовности к обучению в школе у детей старшего дошкольного возраста.
Abbruch und Umnutzung von Gebäuden – Die aktuelle Situation in Deutschland/Demolition and conversion of buildings – The current situation in Germany
Authors: Dorn Charlotte , Otto Jens
Published: September 2024

Im Vergleich zu anderen Wirtschaftsgütern haben Gebäude eine deutlich längere Lebensdauer. Dennoch werden Gebäude häufig vor Erreichen dieser abgebrochen. Die Ursachen dafür sind wissenschaftlich nicht erforscht. Ein Forschungsprojekt der TU Dresden strebt einen umfassenden und differenzierten Überblick über die Faktoren an, die zu vorzeitigem Gebäudeabbruch führen, mit dem übergeordneten Ziel, das Wissen über die Verlängerung der Gebäudenutzungsdauer zu erweitern. Im Zuge des Projekts wurden statistische Daten zu Gebäudeabgängen in Deutschland untersucht. Die Ergebnisse zur Entwicklung der abgebrochenen und nutzungsveränderten Gebäude in Bezug auf Gesamtanzahl, Eigentümer, Baujahr und Ursache sollen in diesem Beitrag vorgestellt werden.
Dashboards in der Batteriezellfertigung/Data acquisition and visualization during the calendering of battery electrodes using a dashboard
Authors: Anderlik Simon , Kößler Florian , Sawodny Julia , Fleischer Jürgen
Published: September 2024

Die Produktivität und die Produktionsqualität in der Batteriezellfertigung hängen derzeit noch stark von der Erfahrung und den Fähigkeiten der Anlagenbediener ab. Dashboards, auf denen prozessrelevante Anlagen- und Qualitätsparameter auf einem Blick angezeigt werden, können hier Abhilfe leisten und das Bedienpersonal unterstützen. Exemplarisch für den Prozessschritt des Kalandrierens wird der Ansatz zum Aufbau eines solchen Dashboards vorgestellt.
KI-Geschäftsmodelle in der Produktion/AI business models in manufacturing – Characteristics of AI business models in manufacturing
Authors: Heider Imanuel , Frisch Marvin , Sawodny Julia , Puchta Alexander , Fleischer Jürgen
Published: September 2024

Das technische Know-How zur Entwicklung und Implementierung eigener KI-Lösungen hat Einzug in Unternehmen der Produktionstechnik gefunden. Eine Herausforderung besteht jedoch fort: Es mangelt an erprobten Geschäftsmodellen, die jenen durch die KI-Applikation generierten Mehrwert an ihre Anbieter weitergeben. In diesem Zusammenhang ist es entscheidend Strategien zu entwickeln, die den KI-Einsatz nicht nur technisch, sondern auch wirtschaftlich und organisatorisch optimieren.