bluuebunny/crossref_metadata_2025 huggingface dataset:
Floxuridine supports UPS independent of germline signaling and proteostasis regulators via involvement of detoxification in C. elegans
Authors: Dubey Abhishek Anil , Sarkar Anwesha , Milcz Karolina , Szulc Natalia A. , Thapa Pankaj , Piechota Małgorzata , Serwa Remigiusz A. , Pokrzywa Wojciech
Published: July 2024

The ubiquitin-proteasome system (UPS) is critical for maintaining proteostasis, influencing stress resilience, lifespan, and thermal adaptability in organisms. In Caenorhabditis elegans, specific proteasome subunits and activators, such as RPN-6, PBS-6, and PSME-3, are associated with heat resistance, survival at cold (4°C), and enhanced longevity at moderate temperatures (15°C). Previously linked to improving proteostasis, we investigated the impact of sterility-inducing floxuridine (FUdR) on UPS functionality under proteasome dysfunction and its potential to improve cold survival. Our findings reveal that FUdR significantly enhances UPS activity and resilience during proteasome inhibition or subunit deficiency, supporting worms’ normal lifespan and adaptation to cold. Importantly, FUdR effect on UPS activity occurs independently of major proteostasis regulators and does not rely on the germ cells proliferation or spermatogenesis. Instead, FUdR activates a distinct detoxification pathway that supports UPS function, with GST-24 appearing to be one of the factors contributing to the enhanced activity of the UPS upon knockdown of the SKN-1-mediated proteasome surveillance pathway. Our study highlights FUdR unique role in the UPS modulation and its crucial contribution to enhancing survival under low-temperature stress, providing new insights into its mechanisms of action and potential therapeutic applications.
Interplay of mental state, personality, and popularity among peers in shaping belongingness of first-year students: A cross-sectional study
Authors: Zhang Audrey , Kazazi Fjorda , Tang Kevin , Howell Peter
Published: July 2024

Belonging to a university shapes wellbeing and academic outcomes for first-year students, yet this belongingness is harder to achieve for those from lower socio-economic backgrounds. This study delved into the flexible construct of status—the individual’s perceived position within the university’s social hierarchy and the strategy they adopt to achieve that position—and its impact on their belongingness. The objective was to identify key psychological contributors that could impact first-year Psychology students expected social status and thereby their belongingness. A cross-sectional study tested first year Psychology students entering university in 2021 and 2022.The first-year students completed a battery of questionnaires to ascertain their status, belongingness to the university, mental state, and personalities. Structural equation modelling (SEM) was employed to evaluate a social ecological model focusing on belongingness. This analysis investigated the mediating role of peer status (popularity among peers) in the relationship between mental state and belongingness, and the moderating influence of personality traits on the connections between mental state and peer status. Both the mediation and moderation effects were statistically significant after adjusting for gender and ethnicity. The findings offer insights into how university administrations can effectively support students, particularly those from lower socio-economic backgrounds, in enhancing their social status among peers and fostering a stronger belongingness, thereby promoting their overall mental wellbeing and success in their academic pursuits.
Early surgical treatment using regional clinical pathways to reduce the length of postoperative hospital stay in hip fracture patients: A retrospective analysis using the Japanese Diagnosis Procedure Combination database
Authors: Nishimura Haruki , Suzuki Hitoshi , Tokutsu Kei , Muramatsu Keiji , Kawasaki Makoto , Yamanaka Yoshiaki , Uchida Soshi , Nakamura Eiichiro , Fushimi Kiyohide , Matsuda Shinya , Sakai Akinori
Published: July 2024

Hip fracture is a common injury in older adults; however, the optimal timing of surgical treatment remains undetermined in Japan. Therefore, this retrospective study aimed to ascertain the rate of early surgery among hip fracture patients and investigate its effectiveness, along with “regional clinical pathways” (patient plan of care devised by Japanese clinicians), in reducing the length of hospital stay (LOS) postoperatively. We hypothesized that performing early surgery along with a regional clinical pathway is effective to reduce the postoperative LOS and complications among hip fracture patients. We examined the data of patients diagnosed with femoral neck and peritrochanteric fractures retrieved from the Japanese Diagnosis Procedure Combination database between April 2016 and March 2018. Patients were divided into the early (43,928, 34%; surgery within 2 days of admission) and delayed (84,237, 66%; surgery after 2 days of admission) surgery groups. The difference in postoperative LOS between the two groups was 3 days (early vs. delayed: 29 days vs. 32 days). The early surgery group had more cases of intertrochanteric fractures (57% vs. 43%) and internal fixation (74% vs. 55%) than did the delayed surgery group. In contrast, the delayed surgery group had more cases of femoral neck fractures (43% vs. 57%) and bipolar hip arthroplasty (25% vs. 42%) or total hip arthroplasty (1.2% vs. 3.0%). Moreover, the early surgery group showed a lower incidence of complications, except anemia (12% vs. 8.8%). Logistic regression analysis using the adjusted model revealed that early surgery and implementation of regional clinical pathways reduced LOS by 2.58 and 8.06 days, respectively (p<0.001). Early surgery and implementation of regional clinical pathways for hip fracture patients are effective in reducing postoperative LOS, allowing regional clinical pathways to have a greater impact. These findings will help acute care providers when treating hip fracture patients.
Tobacco use and its associated factors among students of medical college at tertiary care center of Eastern Nepal
Authors: Adhikari Pratik , Yadav Pramodman Singh , Khadka Rama , Kafle Sujan , Rayamajhi Anusha , Bhurtel Min Raj , Adhikari Santosh , Shrestha Manisha , Chettri Varsha , Upreti Manish , Gautam Prajwal , Dhungana Shreya , Dawadi Suyash , Adhikari Prakriti , Koirala Aakash
Published: July 2024

Background

Despite declining smoking prevalence globally, South Asia faces a rising burden. In Nepal, existing tobacco control laws haven’t curbed use, with 28.9% of young adults engaging in tobacco use. This study investigates tobacco use and associated factors among medical, dental, and nursing students at a Nepalese tertiary care center.

Objective

We aimed to assess tobacco use prevalence and identify factors associated with it among future healthcare professionals, considering their distinct roles in tobacco control. Medical students can contribute through clinical counseling and public health advocacy, dental students through oral health education, and nursing students through patient education and community outreach.

Methods

A cross-sectional study involving 427 medical, dental, and nursing students was conducted. Data was collected using online questionnaires distributed via email and social media. Descriptive statistics and Chi-square tests were used for analysis.

Results

The study found that 45% of participants were aged 22–25, with females comprising the majority (53.2%). Nearly half (49.2%) belonged to the medical faculty, and 24.4% were in their first year. Furthermore, among those who smoke, 53% reported smoking less than 5 cigarettes daily. The analysis revealed significant associations between smoking with age (p = 0.01), year of study (p = 0.001), parental smoking history (p = 0.001), and having friends who smoke (p = 0.001).

Conclusion

Our findings highlight the moderate prevalence of cigarette smoking among medical students, with family and friends emerging as major influences. Stress relief was a common reason, particularly among young females and first-year students. These results emphasize the urgent need for comprehensive tobacco control programs within medical institutions to equip future healthcare professionals to effectively address smoking issues.
The short- and long-run effect of human capital on income inequality: Empirical evidence in the ASEAN region
Authors: Vo Duc Hong , Vo Anh The , Ho Chi Minh
Published: July 2024

Human capital is a nation’s primary source of inner strength to achieve sustainable economic growth and development. Meanwhile, income inequality is a critical issue preventing sustainable economic growth and social transformation, especially in developing countries. This paper investigates the effect of human capital on income inequality in both the short and long term using the mean group, pooled mean group, and threshold regressions for the ASEAN-7 (including Indonesia, Laos, Malaysia, the Philippines, Singapore, Thailand, and Vietnam) from 1992 to 2018. The paper develops a theoretical linkage between human capital and income inequality by combining the learning theory and the Kuznets hypothesis. This linkage is then tested using data from the ASEAN countries. Findings from the paper indicate that human capital reduces income inequality in the short run in the ASEAN countries. However, the effect is reverted in the long run, suggesting that human capital may increase the income gap in these countries. Particularly, the inverted U-shaped relationship between human capital and income inequality is established for the ASEAN countries whose GDP per capita is lower than USD 8.2 thousand per year. In contrast, the U-shaped relationship is found for the countries with income per capital of more than USD 8.2 thousand. All these findings suggest that social policies targeting reducing income inequality should be prioritized and stay at the centre of any economic policies to achieve sustainable economic growth and development in the ASEAN countries.
Forest topsoil salvage and placement depth affects oil sands reclamation in the boreal forest
Authors: Mackenzie Dean D. , Naeth M. Anne
Published: July 2024

Reclamation of disturbances from oil sands mining requires effective soil management to ensure successful plant establishment and to promote recovery of native plant communities. In this study we investigated the effects of salvage depths (shallow vs. deep) and placement depths (shallow vs. deep) of forest topsoil on plant establishment, species richness, and soil properties in two substrate types (sand and peat-mineral). Shallow salvage led to greater tree stem densities and higher canopy cover for most plant groups, although there was no significant difference in species richness between shallow and deep salvages. Deep placement generally resulted in greater canopy cover, while its effect on plant density was very small for most plant groups. On peat-mineral substrate, fewer differences were detected between shallow and deep salvage, and multiple treatments resulted in greater cover. Findings suggest that a balance between maximizing the area over which propagules are redistributed and providing sufficient resources for successful plant establishment is necessary. Forest topsoil from shallow salvages and deep placements is recommended when targeting increased site productivity and species diversity. In contrast, deep salvage should be used when the primary objective is to obtain maximum reclamation material volume. Salvage depth effects may be influenced by substrate type, with peat-mineral substrate providing more favourable conditions for plant establishment. Further research is needed to assess the long-term impacts of different salvage and placement depths on plant community development and the potential effects of substrate properties on soil and plant response.
Single-cell transcriptome analysis reveals distinct cell populations in dorsal root ganglia and their potential roles in diabetic peripheral neuropathy
Authors: Guo Guojun , Chen Jing , Shen Qixiao , Chen Zhenbing
Published: July 2024

Diabetic peripheral neuropathy (DPN) is a common complication associated with diabetes, and can affect quality of life considerably. Dorsal root ganglion (DRG) plays an important role in the development of DPN. However, the relationship between DRG and the pathogenesis of DPN still lacks a thorough exploration. Besides, a more in-depth understanding of the cell type composition of DRG, and the roles of different cell types in mediating DPN are needed. Here we conducted single-cell RNA-seq (scRNA-seq) for DRG tissues isolated from healthy control and DPN rats. Our results demonstrated DRG includes eight cell-type populations (e.g., neurons, satellite glial cells (SGCs), Schwann cells (SCs), endothelial cells, fibroblasts). In the heterogeneity analyses of cells, six neuron sub-types, three SGC sub-types and three SC sub-types were identified, additionally, biological functions related to cell sub-types were further revealed. Cell communication analysis showed dynamic interactions between neurons, SGCs and SCs. We also found that the aberrantly expressed transcripts in sub-types of neurons, SGCs and SCs with DPN were associated with diabetic neuropathic pain, cell apoptosis, oxidative stress, etc. In conclusion, this study provides a systematic perspective of the cellular composition and interactions of DRG tissues, and suggests that neurons, SGCs and SCs play vital roles in the progression of DPN. Our data may provide a valuable resource for future studies regarding the pathophysiological effect of particular cell type in DPN.
The political preferences of LLMs
Authors: Rozado David
Published: July 2024

I report here a comprehensive analysis about the political preferences embedded in Large Language Models (LLMs). Namely, I administer 11 political orientation tests, designed to identify the political preferences of the test taker, to 24 state-of-the-art conversational LLMs, both closed and open source. When probed with questions/statements with political connotations, most conversational LLMs tend to generate responses that are diagnosed by most political test instruments as manifesting preferences for left-of-center viewpoints. This does not appear to be the case for five additional base (i.e. foundation) models upon which LLMs optimized for conversation with humans are built. However, the weak performance of the base models at coherently answering the tests’ questions makes this subset of results inconclusive. Finally, I demonstrate that LLMs can be steered towards specific locations in the political spectrum through Supervised Fine-Tuning (SFT) with only modest amounts of politically aligned data, suggesting SFT’s potential to embed political orientation in LLMs. With LLMs beginning to partially displace traditional information sources like search engines and Wikipedia, the societal implications of political biases embedded in LLMs are substantial.
Evaluating the competency of ChatGPT in MRCP Part 1 and a systematic literature review of its capabilities in postgraduate medical assessments
Authors: Vij Oliver , Calver Henry , Myall Nikki , Dey Mrinalini , Kouranloo Koushan
Published: July 2024

Objectives

As a large language model (LLM) trained on a large data set, ChatGPT can perform a wide array of tasks without additional training. We evaluated the performance of ChatGPT on postgraduate UK medical examinations through a systematic literature review of ChatGPT’s performance in UK postgraduate medical assessments and its performance on Member of Royal College of Physicians (MRCP) Part 1 examination.

Methods

Medline, Embase and Cochrane databases were searched. Articles discussing the performance of ChatGPT in UK postgraduate medical examinations were included in the systematic review. Information was extracted on exam performance including percentage scores and pass/fail rates.

MRCP UK Part 1 sample paper questions were inserted into ChatGPT-3.5 and -4 four times each and the scores marked against the correct answers provided.

Results

12 studies were ultimately included in the systematic literature review.

ChatGPT-3.5 scored 66.4% and ChatGPT-4 scored 84.8% on MRCP Part 1 sample paper, which is 4.4% and 22.8% above the historical pass mark respectively. Both ChatGPT-3.5 and -4 performance was significantly above the historical pass mark for MRCP Part 1, indicating they would likely pass this examination.

ChatGPT-3.5 failed eight out of nine postgraduate exams it performed with an average percentage of 5.0% below the pass mark.

ChatGPT-4 passed nine out of eleven postgraduate exams it performed with an average percentage of 13.56% above the pass mark. ChatGPT-4 performance was significantly better than ChatGPT-3.5 in all examinations that both models were tested on.

Conclusion

ChatGPT-4 performed at above passing level for the majority of UK postgraduate medical examinations it was tested on. ChatGPT is prone to hallucinations, fabrications and reduced explanation accuracy which could limit its potential as a learning tool. The potential for these errors is an inherent part of LLMs and may always be a limitation for medical applications of ChatGPT.
Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation
Authors: Cable Jana M. , Reinoso-Vizcaino Nicolás M. , White Robert E. , Luftig Micah A.
Published: July 2024

Epstein-Barr Virus (EBV) is associated with numerous cancers including B cell lymphomas. In vitro, EBV transforms primary B cells into immortalized Lymphoblastoid Cell Lines (LCLs) which serves as a model to study the role of viral proteins in EBV malignancies. EBV induced cellular transformation is driven by viral proteins including EBV-Nuclear Antigens (EBNAs). EBNA-LP is important for the transformation of naïve but not memory B cells. While EBNA-LP was thought to promote gene activation by EBNA2, EBNA-LP Knockout (LPKO) virus-infected cells express EBNA2-activated cellular genes efficiently. Therefore, a gap in knowledge exists as to what roles EBNA-LP plays in naïve B cell transformation. We developed a trans-complementation assay wherein transfection with wild-type EBNA-LP rescues the transformation of peripheral blood- and cord blood-derived naïve B cells by LPKO virus. Despite EBNA-LP phosphorylation sites being important in EBNA2 co-activation; neither phospho-mutant nor phospho-mimetic EBNA-LP was defective in rescuing naïve B cell outgrowth. However, we identified conserved leucine-rich motifs in EBNA-LP that were required for transformation of adult naïve and cord blood B cells. Because cellular PPAR-g coactivator (PGC) proteins use leucine-rich motifs to engage transcription factors including YY1, a key regulator of DNA looping and metabolism, we examined the role of EBNA-LP in engaging transcription factors. We found a significant overlap between EBNA-LP and YY1 in ChIP-Seq data. By Cut&Run, YY1 peaks unique to WT compared to LPKO LCLs occur at more highly expressed genes. Moreover, Cas9 knockout of YY1 in primary B cells prior to EBV infection indicated YY1 to be important for EBV-mediated transformation. We confirmed EBNA-LP and YY1 biochemical association in LCLs by endogenous co-immunoprecipitation and found that the EBNA-LP leucine-rich motifs were required for YY1 interaction in LCLs. We propose that EBNA-LP engages YY1 through conserved leucine-rich motifs to promote EBV transformation of naïve B cells.
Methodology of the national mapping of educational theatre programmes
Authors: Cziboly Ádám , Bethlenfalvy Ádám
Published: July 2024

During the second half of the 2012–13 theatre season, we mapped all then-existing educational theatre practices in Hungary against a standardized set of criteria. We contacted a total of 298 institutions and observed 118 programmes in person. We aimed to map the complete picture, so we involved every programme that fitted our low-threshold criteria and responded to our inquiry. Presumably, we covered the entire Hungarian educational theatre sphere. For each programme, we collected data from six sources: children or youth participating in the programmes; teachers accompanying the participants; organizational contact persons; creators/performers of the programmes; observing of the programmes by independent observers; and secondary research on the internet. In 2023, we repeated part of this data collection. In this article, we present the methodology used for the mapping in detail since we believe it can serve as a model for similar mappings in other countries.
In the dead time: The unfacilitated encounters among participants of the Oberammergau Passion Play
Authors: Leffler Elliot , Ohm William
Published: July 2024

The 2022 Oberammergau Passion Play – a giant applied theatre project with almost 2000 participants, running for 110 performances over five months with a run time of over 5 hours – provides an opportunity to study how community participants use applied theatre’s ‘dead time’: the unstructured, unfacilitated time between onstage appearances. This study argues that in the tight spaces backstage, participants talk, play and engage in acts of care and mentorship, imbuing the dead time with tremendous social value. In fact, much to the initial surprise of the authors, most participants described their interest in the project as being primarily anchored in this dead time, rather than the staged action. These findings leave us with many salient questions for the field of applied theatre, and more research will be needed across varying contexts to better understand how to mitigate the social risks of dead time while invigorating its community-building potential.
Intermedial and theatrical perspectives of AI: Re-framing the Turing test
Authors: Timplalexi Eleni , Rizopoulos Charalampos
Published: July 2024

Artificial intelligence (AI), the understanding and building of computational agents that act intelligently, is claimed to be a powerful, pervasive medium. Although we interact with it and hear a lot about it, we do not ‘see’ AI but experience its manifestations and/or outcomes, such as chatterbots and virtual assistants. A criterion for deeming an artificial agent as intelligent has been already proposed by Turing in 1950, coined as the ‘Imitation Game’, where a machine takes the place of a man, known as the Turing test. Despite the test being initially conceived as a make-believe game, AI has been enmeshed in major fields of human social activity and co-determines our lives. In this article, AI is compared with the media type of theatre performance, the epitome of make-believe, on the basis of intermediality. Furthermore, the analogies between AI and theatre are discussed and the paradigm of the puppet theatre as well as the medium of the mask prevail in the analysis. Findings are discussed, especially in light of the mind–body split and the alignment problem, and their implications are contemplated, allowing a re-estimation and re-framing of the Turing test in its theatrical and performative dimension.
Artificial intelligence in Departments of Communication: A course proposal
Authors: Connor Kelley E. , Cali Dennis D.
Published: July 2024

When communication and mass media faculty returned from a kind of exile that COVID-19 had inflicted on them, they were hit almost immediately with the phenomenon of artificial intelligence (AI). The fall semester of 2023 seemed to usher in a new means by which students would complete assignments that left faculty scratching their heads. They faced a new form of information retrieval that students (as well as faculty) were using that, at once, yielded more substantive prose while at the same time posed new questions about authorship, trust, reliability, bias and even personhood. The discipline of communication and media studies bears a particular responsibility to contemplate the massive change underway with the use of AI. Most of us in the field have dedicated our careers to considering the human-media-culture interface. Media ecologists, in particular, routinely explore how media shape culture, conscience and communication. Yet many of us have not known what to make of the phenomenon suddenly surging in academics and in all sectors of society. This article seeks to offer a framework, cultivated out of media ecological sensibilities, for critically examining implications of AI in the realm of communication. Specifically, we have designed a graduate course that takes up the major lines of inquiry into how AI challenges conventions and urges new paradigms in our discipline. Our article offers a course proposal that communication faculty can adopt to their curriculum. It consists of a sample course syllabus, recommended textbooks and YouTube videos, sample assignments, a review of major AI themes in scholarly and trade journals, a suggested media ecology tool for critical application (the Tetrad), and an extensive bibliography. The overall objective of our course proposal is to guide reflection on the implications of AI in various communication contexts and environments.
The Future of the Professions: How Technology Will Transform the Professions, Richard Susskind and Danel Susskind (2015)
Authors: Ward Joel S.
Published: July 2024

Review of: The Future of the Professions: How Technology Will Transform the Professions, Richard Susskind and Danel Susskind (2015)

Oxford: Oxford University Press, 346 pp.,

ISBN 978-0-19871-339-5, h/bk, USD 22.95
Body on the Barricades: Life, Art, and Resistance in Contemporary India, Brahma Prakash (2023)
Authors: Kapur Jyotsna
Published: July 2024

Review of: Body on the Barricades: Life, Art, and Resistance in Contemporary India, Brahma Prakash (2023)

Delhi: LeftWord Books, 210 pp.,

ISBN 978-9-39201-810-7, p/bk, $18
A incrível história de um manuscrito da Septvaginta quase destruído na Guerra Civil Espanhola (BH UCM 22 = 442 Rahlfs)
Authors: Jesus Carlos A. Martins de
Published: July 2024

The aim of this paper is to present and discuss a newly recovered manuscript of the Septuagint (BH UCM 22 = 442 Rahlfs), a codex sent by the Senate of Venice to Cardinal Cisneros to help the editorial tasks for the Greek column of the Poliglota Complutensis. By considering the manuscript’s external evidences and history of transmission, as well as looking closely at its marginal and interlinear additions and corrections, it shall be demonstrated that it was largely reviewed by Marcus Musurus – who is known to have helped Andreas Asolanus in printing the Aldine Greek Bible (1518) – and by other two (or even three) Hellenists, both in Venice and in Alcalá. This, alongside the data of some preliminary textual collation, confirm the use of the Madrid codex for the editorial process of the two first complete editions of the Bible, mostly contemporary, by Aldus’ house and Cisneros’ team of Hellenists.
Memorias desde la periferia gallega: Entrevista a María Luisa García Gil
Authors: Blanco Agüeira Silvia
Published: July 2024

La obra de María Luisa García Gil es relevante por su sensibilidad hacia el paisaje y el medio rural gallego. Arquitecta nacida el 10 de octubre de 1949 en Madrid, se trasladó en 1976 a la periferia peninsular, en plena transición española, época caracterizada por la escasez de mujeres en el pleno ejercicio de la profesión, a pesar de su progresiva incorporación a los estudios acreditados de arquitectura.
Women Architects and Social Housing in the Basque Country (1978-2008). An Approach from a Feminist Perspective
Authors: Ocerin-Ibáñez Olatz , Rodríguez-Oyarbide Itziar
Published: July 2024

This article addresses the presence of women architects in social housing in the Basque Country between 1978 and 2008 from a feminist perspective. To this end, the first section of the paper is devoted to the figure of the architect Margarita Mendizábal, in order to display the unequal and male-dominated professional context that the Basque architect found after her graduation in 1956. In 1978, after two decades in the profession, Mendizábal designed a project to build a hundred social housing units in Madrid, in fact, the largest social housing project that she developed during her professional career. Until the early seventies there is no woman working as freelance architect in the Basque Country. In 1977, the School of Architecture of the UPV/EHU (University of the Basque Country) was created; this fact worked as an activating agent for the presence of women architects after the beginning of the nineties. In this regard, the last section of this article provides statistical data to quantify the presence of women architects in the Basque Country. This data gathers information related to women architects teaching at the School of Architecture of the UPV/EHU, in the professional sphere as freelance architects belonging to the Basque-Navarre Architects Association (COAVN) and, finally, in designing social housing developed by the Basque Government after taking over this area in 1981. The quantification of women out of total social housing developments shows that there are many fewer female than male architects working in this field. Furthermore, we provide a series of social housing cases authored or co-authored by women architects that show a relevant contribution to architecture and architectural culture in the Basque Country.
Aproximaciones a H.I.J.O.S Mar del Plata (Buenos Aires, Argentina)
Authors: Zubillaga Paula
Published: July 2024

El presente trabajo se acerca a los orígenes y primeros años de Hijos e Hijas por la Identidad y la Justicia contra el Olvido y el Silencio (H.I.J.O.S) Regional Mar del Plata (Provincia de Buenos Aires, Argentina). Se trata de una agrupación surgida a nivel local en el año 1994, que tuvo su aparición pública en el año 1995 y que luego se fragmentó y dio origen a dos organizaciones. Observaremos el perfil de sus integrantes, algunas de sus acciones colectivas, el funcionamiento interno y los vínculos con otras organizaciones del movimiento de derechos humanos de esa ciudad turística, como la Asamblea Permanente por los Derechos Humanos, Familiares de Detenidos Desaparecidos y Madres de Plaza de Mayo. Asimismo, daremos cuenta de algunas similitudes y diferencias con otras regionales de dicha agrupación con las cuales se vincularon rápidamente a partir de los Encuentros Nacionales y que han sido estudiadas por otros autores, como La Plata, Córdoba, Rosario, Santa Fe, Tucumán y la Ciudad Autónoma de Buenos Aires (Capital Federal de la Argentina). Para tal fin, utilizaremos diversas fuentes, como: testimonios orales del Programa de Derechos Humanos de la Biblioteca Nacional y del Archivo Oral Memoria Abierta; prensa local y nacional (digital, audiovisual y escrita); documentos de inteligencia de la policía de la Provincia de Buenos Aires; producción artística de integrantes de la regional de H.I.J.O.S; ordenanzas de la municipalidad de General Pueyrredón; páginas web y bibliografía específica.
ESPINO JIMÉNEZ, Francisco Miguel, De la fiesta a lo cotidiano y del liceo a la taberna. Ocio, cultura y costumbres en la España liberal a través de una provincia, la Córdoba isabelina y romántica. Madrid, Sílex, 2022, 473 pp.
Authors: De Luis Martín Francisco
Published: July 2024

Reseña del libro: Espino Jiménez, Francisco Miguel, De la fiesta a lo cotidiano y del liceo a la taberna. Ocio, cultura y costumbres en la España liberal a través de una provincia, la Córdoba isabelina y romántica. Madrid, Sílex, 2022, 473 pp. ISBN: 978-84-19077-96-7.
Biometric analysis of Palmer mangoes
Authors: Martins Freitas Rutinéia , Silva Peixoto Lucas , Rodrigues de Oliveira Hygor , Resende Osvaldo , Rocha Plácido Geovana , Fonseca Souza Alex , Moresco Karla Suzana , Romani Viviane Patrícia
Published: July 2024

damages, resulting in a substantial waste of approximately 30% of the production. Among widely marketed varieties, the 'Palmer' cultivar stands out due to its flavor and coloration. The efficiency in the transportation and storage of these fruits is intricately linked to various attributes, especially their physical characteristics. In this context, the present study conducted a biometric evaluation of 145 'Palmer' mangoes harvested in Coxim, Mato Grosso do Sul. Parameters such as weight, length, width, and thickness of the fruits were analyzed using a semi-analytical balance and caliper. The results revealed that the mangoes produced in Coxim weigh around 396 g, with a length of 13 cm, width of 8 cm, and thickness of 7.5 cm. These measurements are smaller than the commercially marketed fruits of the same variety but larger than those of the Espada, Rosa, and Van Dyke varieties. Additionally, all analyzed variables showed a positive correlation, indicating that as one variable increases, the others also increase. This underscores the importance of special care in handling fruits throughout the supply chain, given their density of 0.534 g/cm³ and extensive contact area. These findings emphasize the pressing need for improvements in packaging, transportation, and storage processes to reduce losses and waste, thereby contributing to a more efficient and sustainable management in the mango supply chain.
Cultura e religiosidade popular na Alta Idade Média
Authors: Pedrazzi Chacon Marcos
Published: July 2024

O presente artigo discute a temática da cultura e religiosidade popular e como tal conceito pode ser utilizado na análise de fontes alto medievais, em especial, aquelas compostas por sermões. Assim, traça-se um panorama marcado por estudos interdisciplinares que buscaram definir o que seria o “popular”, quem integraria a categoria “povo” e como se dariam as trocas entre os níveis culturais. No campo dos estudos medievais, destacam-se três correntes principais, que tomam a cultura popular, respectivamente, enquanto: a cultura das massas, leigos e iletrados, oposta intrinsecamente à cultura erudita, clerical e letrada; um ponto de encontro, trocas significativas e conflitos entre a cultura folclórica e a de elite/formal; uma arena sistemática de conflitos entre a cultura subalterna e a dominante. Por fim, analisando passagens representativas dos sermões do bispo Cesário de Arles (c. 470-542), conclui-se que a segunda corrente se mostra a mais apropriada para tal estudo, visto que as práticas populares são potentes o suficiente para transpor barreiras de classe e status.
marcas da hanseníase em Goiás
Authors: Antonio Gonçalves Teixeira Ricardo , De Medeiros Silva João Justino , Cavalcanti Teixeira Rayane , Pinto Samuel
Published: July 2024

A hanseníase, uma afecção que ao longo da história foi referida como Lepra, representa uma das mais antigas moléstias registradas pela civilização, afetando a humanidade em diversas partes do globo ao longo dos séculos. Esta condição, frequentemente marginalizada e envolta em estigma, é identificada pela Sociedade Brasileira de Dermatologia como uma doença negligenciada, o que sublinha a necessidade de uma maior atenção e recursos dedicados ao seu diagnóstico, tratamento e à educação do público sobre suas causas e efeitos. No Brasil, a abordagem adotada no combate à hanseníase, e endossada por setores da comunidade médica, baseou-se no isolamento, segregação e exclusão social dos indivíduos diagnosticados com a doença, assim como de seus descendentes. Esta prática, de natureza eugênica, visava a contenção e o controle da enfermidade, sendo considerada uma estratégia profilática. A política implementada não apenas refletiu uma tentativa de gestão sanitária, mas também impôs um grave estigma social aos afetados, marcando profundamente a história do tratamento da hanseníase no país. No leprosário Colônia Santa Marta, desde sua fundação em 1943, religiosos e religiosas transcenderam suas funções espirituais para assumir papéis cruciais em áreas como enfermagem, educação e treinamento para atividades profissionais, entre outras. O presente artigo buscou compreender o valor reconhecido a Monsenhor Rodolfo Tellmann tanto pelos sobreviventes da internação compulsória na Colônia Santa Marta quanto pelos membros religiosos afiliados à Igreja Católica, em relação ao trabalho realizado junto aos indivíduos afetados pela hanseníase. Nesse sentido, propomos conduzir um estudo de caráter qualitativo, selecionando, além de documentos históricos, a narrativa oral como uma fonte primordial para acessar histórias e memórias. A pesquisa revelou que Rodolfo Tellmann teve um papel fundamental não apenas na missão religiosa que lhe foi delegada, mas também em promover uma abordagem humanizada e concreta junto à comunidade de hansenianos. Por meio de suas ações, proporcionou motivação, capacitação profissional, esperança e uma significativa melhoria na qualidade de vida desses indivíduos.
Consequências da Guerrilha do Araguaia para os Indígenas Aikewara
Authors: Gomes Araújo Vanalda
Published: July 2024

Este artigo tem como objetivo debater as consequências culturais, territoriais e psicológicas para o povo Aikewara com a Guerrilha do Araguaia. Este fenômeno histórico que ocorreu no Sudeste do Pará no período entre os anos de 1970 a 1975, época em que o Brasil vivia sob o Regime Militar, ficou durante vários anos esquecido na história do país, mas veio à tona a partir de 2014 com a instalação da Comissão Nacional da Verdade – CNV.  Com a instalação da CNV, as investigações foram divididas por setores e um deles investigou a participação dos Indígenas e as consequências sofrida por eles. Para realização deste artigo, optamos pela metodologia de pesquisa documental, como também revisão bibliográfica de materiais produzidos por outros pesquisadores. Apresentamos os resultados desta pesquisa através deste artigo.
Palavras-chave: Aikewara. Guerrilha do Araguaia. Território.
Ensino Religioso e sua construção epistemológica em teses e dissertações no Estado de Goiás
Authors: De Souza e Silva Ana Maria , Mota de Castro Raimundo Márcio
Published: July 2024

Este artigo apresenta os resultados obtidos através de pesquisa realizada no Programa de Pós-Graduação Stricto sensu (XXX) da Universidade (XXX). A dissertação desenvolvida foi defendida no ano de (XXX) e buscou desvelar as configurações existentes na produção acadêmica em níveis de Mestrado e Doutorado sobre o Ensino Religioso que tenham sido produzidas no Estado de Goiás entre 1997 e 2021. Para alcançar tal objetivo, tentamos nos aproximar do Método Fenomenológico, através do procedimento de revisão bibliográfica de caráter exploratório e abordagem qualitativa. Os debates teóricos utilizaram autores como Bhabha (2019), Hall (2020), Koselleck (2014), Junqueira, Rodrigues e Martins Filho (2015), entre outros. Os resultados obtidos foram apresentados através da proposta de Gilles e Deleuze (2019) de Cartografia Social, isto é, as análises se organizaram através do mapeamento do fenômeno estudado. Concluímos, assim, que o Ensino Religioso percorreu trajetos conflituosos em sua história, mas isso garantiu que suas possibilidades de ensino-aprendizagem se comportem enquanto dispositivos de interação e intervenção social. Afirmamos, ainda, que repensar a epistemologia do Ensino Religioso através das produções acadêmicas permite reconstruir o espaço escolar para o encontro entre as diversidades culturais e diálogo entre elas.
Iatrogenic Atrial Septal Defect After MitraClip Transcatheter Edge-to-Edge Repair: To Close or Not to Close?
Authors: Abdelsalam Mariem , Younus Raghad , Abdalla Lamis F. , Almanfi Abdelkader
Published: July 2024

The evolution of percutaneous procedures that use transseptal puncture to treat left-sided structural heart disease has led to the emergence of iatrogenic atrial septal defects as a potential complication. These defects can result in hemodynamic decompensation and worsening clinical outcomes. Some iatrogenic atrial septal defects require immediate closure, others do not. This case report presents 2 patients who underwent transcatheter edge-to-edge mitral valve repair with transseptal puncture and required iatrogenic atrial septal defect closure (1 immediate and 1 delayed). The goal of this report is to highlight iatrogenic atrial septal defect assessment and the possible need for closure after transseptal puncture.
Experimental studies and identifying a model of the dynamic system “anti-vibration seat – operator” of a mobile machine.
Authors: Abyzov A.A. ,   South Ural State University, Chelyabinsk, Russia, Muhiddinzoda K.Dzh. ,   South Ural State University, Chelyabinsk, Russia
Published: July 2024

When creating new types of transport and technological mobile machines, it is important to ensure compliance with sanitary standards for vibrations at the driver’s seat. Anti-vibration seats are widely used to reduce vibrations transmitted from the engine and chassis of the machine to the operator's workplace. When designing a machine, mathematical modeling can be used to make a reasonable choice of seat parameters. Since the anti-vibration seat together with the operator’s body form a single dynamic system, the mathematical model must include both the anti-vibration seat and the operator’s body. The article presents an overview of mathematical models that describe vertical vibrations of the seated body. It describes an experimental setup for studying the dynamics of a human operator sitting in an anti-vibration seat. The experimental setup includes an electrodynamic vibration bench produced by LDS, control and recording equipment. The studies were carried out for the Sibeco anti-vibration seat. During testing, the base of the seat performed vertical harmonic vibrations with a gradually increasing frequency, while the amplitude of vibration accelerations was maintained constant. The accelerometers installed on the seat elements, on a special disk located on the seat cushion and on the operator’s body, recorded vibrations of these elements. As a result of processing experimental data, transfer functions were obtained. They connect the amplitudes of movement of various elements of the model with movements of the base in a given frequency range. The experiments were carried out with the participation of testers with different body weights. The article proposes a mathematical model that describes the vertical vibrations of the “vibrationprotective seat – operator’s body” system. The inertial and elastic-damping characteristics of the seat elements were determined earlier during special tests. Based on a comparison of calculated and experimental data, the parameters of the model elements describing the operator’s body were refined. The parameters of the mathematical model obtained during the study will be used in the future research for calculation estimates of the vibration load of the operator’s workplace.
A method for mathematical modeling of the hydrodynamic friction of plunger pairs in terms of microgeometry
Authors: Zhumadilov M.D. ,   Altai Geophysical Plant LLC, Barnaul, Russia, Lukyanov A.V. , Gavrilov K.V. , Umurzakov I.K. ,   Altai Geophysical Plant LLC, Barnaul, Russia,   South Ural State University, Chelyabinsk, Russian Federation,   South Ural State University, Chelyabinsk, Russian Federation
Published: July 2024

The fuel injection system strongly relies on a high pressure fuel pump which is essential for its overall performance. The fuel pump plunger is subject to high loads and irregular lubrication under dynamic loads, which leads to its premature wear. The industrial sector uses laser surface micro-texturing to reduce friction and improve anti-wear properties. Its positive effects are supported by both theoretical and experimental data. The paper presents a method for determining the hydromechanical characteristics of plunger pairs during hydrodynamic friction. The microgeometry of friction surfaces was taken into account due to the lubricating fluid cavitation effect described by the modified Reynolds equation. The proposed method can be applied to develop the software to analyze the contacting surfaces of plunger pairs and evaluate their tribological characteristics based on the microgeometry parameters of friction surfaces. The paper also studies the influence of microgeometry parameters on the quality criteria of the hydromechanical characteristics of plunger pairs. It gives the calculated examples of analyzing the contacting surfaces of plunger pairs separated by a lubricant layer. The technical specifications are assessed depending on the microgeometry parameters of the friction surface roughness.
Exposure to neonicotinoid pesticides induces physiological disorders and affects color performance and foraging behavior in goldfish
Authors: Kakuta Izuru , Takase Kiyomi
Published: July 2024

We investigated the effects of neonicotinoid pesticides (NEOs) on the spontaneous swimming and foraging behavior, as well as the morphological and physiological changes of goldfish. Most fish reared in thiamethoxam (THM)‐sprayed rice fields showed the scales easily peeled off, and increased ascites. Some individuals showed decreased bio‐defense activity and low plasma Ca2+. Similar changes were found in the exposure test to THM (1.0 and 20.0 μg/L) and dinotefuran (1.2 and 23.5 μg/L). Next, the effects of a low concentration of THM (1.0 μg/L) on the spontaneous swimming and foraging behavior of fish were examined. Fish exposed to THM for 1 week became restless and had increased the swimming performance, especially under natural light, white LED lighting and blue LED lighting. Goldfish exposed to THM had also increased intake of shiny white beads under green LED illumination. These results indicate that the exposure to NEO, even for a short period and at low levels, not only suppressed bio‐defense activities and metabolic abnormalities, but also stress response, the swimming and foraging behavior of the fish are likely to be significantly suffered.
Normalized solutions for Sobolev critical fractional Schrödinger equation
Authors: Li Quanqing , Nie Jianjun , Wang Wenbo , Zhou Jianwen
Published: July 2024

In the present study, we investigate the existence of the normalized solutions to Sobolev critical fractional Schrödinger equation:

(

−
Δ

)

s

u
+
λ
u
=
f

(

u

)

+

∣
u
∣

2

s

*

−
2

u
,

in

R

N

,

(

P

m

)

∫

R

N

∣
u
∣

2

d
x
=

m

2

,

\hspace{14em}\left\{\begin{array}{ll}{\left(-\Delta )}^{s}u+\lambda u=f\left(u)+{| u| }^{{2}_{s}^{* }-2}u,\hspace{1.0em}& \hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}{{\mathbb{R}}}^{N},\hspace{12em}<mml:mpadded xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
voffset="-2.9ex">\left({P}_{m})\\ \mathop{\displaystyle \int }\limits_{{{\mathbb{R}}}^{N}}{| u| }^{2}{\rm{d}}x={m}^{2},\hspace{1.0em}\end{array}\right.

where

0
<
s
<
1

0\lt s\lt 1

,

N
≥
2

N\ge 2

,

m
>
0

m\gt 0

,

2

s

*

≔

2
N

N
−
2
s

{2}_{s}^{* }:= \frac{2N}{N-2s}

,

λ

\lambda

is an unknown parameter that will appear as a Lagrange multiplier, and

f

f

is a mass supercritical and Sobolev subcritical nonlinearity. Under fairly general assumptions about

f

f

, with the aid of the Pohozaev manifold and concentration-compactness principle, we obtain a couple of the normalized solution to

(

P

m

)

\left({P}_{m})

. We mainly extend the results of Appolloni and Secchi (Normalized solutions for the fractional NLS with mass supercritical nonlinearity, J. Differential Equations 286 (2021), 248–283) concerning the above problem from Sobolev subcritical setting to Sobolev critical setting, and also extend the results of Jeanjean and Lu (A mass supercritical problem revisited, Calc. Var. 59 (2020), 174) from classical Schrödinger equation to fractional Schrödinger equation involving Sobolev critical growth. More importantly, our result settles an open problem raised by Soave (Normalized ground states for the NLS equation with combined nonlinearities: The Sobolev critical case, J. Funct. Anal. 279 (2020), 108610), when

s
=
1

s=1

.