bluuebunny/crossref_metadata_2025 huggingface dataset:
Locality and Non locality
Authors: Barukčić Ilija
Published: November 2020

Aim: Whether, under all the circumstances considered, a relativistic concept of locality and non-locality may fully reproduce the quantum probabilities for outcomes of experiments, is re-investigated.Methods: The usual methods and rules of statistics, probability theory and quantum mechanics were used. Results: The interior logic of the variance has been re-investigated. A relationship between the Pythagorean theorem and the variance has been established. A n-dimensional Pythagorean theorem has been derived. The problem of locality and non-locality and the relationship to the variance has been analysed.Conclusion: It may no longer stay an open question how to deal with the notions of locality and non-locality.
Functional Domains in the Encrypted Inverse Fine-Structure Constant
Authors: Sluyser Mels
Published: November 2020

The inverse fine-structure constant 1/α = 137.035999… … is encrypted by a numerical 137 035 999 … … triplet code, and functional domains of this code are separated from each other by 999 triplets.
Transmission of Wellness Information Signals Using an Inerton Field Channel
Authors: Krasnoholovets Volodymyr , Fedorivsky Vasyl
Published: November 2020

We examine the nature of field signals capable to correct the functioning of the human body and the possibility to transmit such signals from a remote source. To understand this, the matter wave (i.e. the particle’s wave y-function) is expanded in two subsystems: the particle itself and a cloud of spatial excitations named inertons. They are inertons that carry fragments of mass and provide a short-range action between adjacent atoms. The existence of inertons has already been confirmed in many experiments. A system of entities (atoms or molecules) is filled with their own inertons and such system has to be considered as a casing filled with an inerton gas. These inertons indeed behave like a gas that fluctuates at the same frequencies as the molecules of the casing. It was shown previously that inertons periodically come from the mass state m to the tension state x. This means that inertons behave as a typical wave oscillating between the compression and stretching. Inerton wavelets are capable of being emitted from the system of vibrating entities. It is demonstrated that inerton wavelets can carry information to a remote receptor (distant even by many kilometres) transmitting to it the necessary information signals.
New Thermodynamics: Inelastic Collisions, Blackbody Radiation, Entropy and Light
Authors: Mayhew Kent W.
Published: November 2020

Most collisions that we witness are inelastic. Irrationally, the sciences have evolved around elastic collisions, which allows for simpler mathematical modelling. Since a result of inelastic collisions are photons, we examine the feasibility of an ensemble of inelastic collisions producing a blackbody spectrum. This will lead to reconsideration of how the light that governs our lives is produced, i.e., light from both the stars and incandescent lightbulbs.

A brief discussion of entropy being a mathematical contrivance based upon elastic collisions is included. A consequence of collisions being inelastic becomes, entropy can only be an approximation when applied to the real world. And this fits well with “New Thermodynamics”.
Struktur dan Nilai Sosial dalam Dongeng Cinderella dan Cerita Putri Arabella : Kajian Sastra Bandingan
Authors: Nanda Ega Setia , Hayati Yenni
Published: November 2020

Children literature have long been believed to contain values that contribute to shaping the character of the young reader. The children fiction from many countries always offer noble values that can influence the character formation. This study discusses social values in the Cinderella fairy tale (Indonesian version) and the story of Putri Arabella (the Malaysian version). This study used a comparative literature approach to obtain a comprehensive comparison between the fairy tales of Cinderella and Putri Arabela. The data were analyzed using the content analysis method to obtain a sharper and deeper meaning behind the qualitative data in the form of words, phrases, dialogues and narratives. The results of the data analysis found that the two stories both contained social values, the value of compassion, advice to help others, and a sense of responsibility. Besides having similarities, these two stories also contain differences. The differences were found in the characterization and setting of the story. This is because this story originates from two different countries which contain different social conditions.
Teacher's Reinforcement in Teaching English at High School Level
Authors: Frahesti Dian , Natasha Harum
Published: November 2020

This study aims to determine the teacher's reinforcement in teaching English at the high school level. This is important to do because strengthening is one of the strategies that teachers can apply in increasing interest and motivation to learn to achieve satisfactory student achievement. This research uses qualitative methods with descriptive techniques. In data collection, researchers conducted interviews and observations on teachers of SMA Islam Negeri 2 Kuantan Singingi to determine the components of reinforcement used by teachers in learning English. The results of this study indicate that the English teacher uses verbal and non-verbal reinforcement in learning English. For verbal reinforcement, the teacher uses reinforcement with words and reinforcement with sentences. For non-verbal reinforcement, the teacher uses gesture reinforcement, closeness strengthening, contact strengthening, activity reinforcement, and token reinforcement. The reinforcement most often used by teachers in teaching English was reinforcement with words, while the reinforcement that was rarely used by teachers was token reinforcement.
Editorial ReDeA Nº 16
Authors: Revista Derechos en Acción
Published: November 2020

Editorial ReDeA Nº 16.
Derecho penal y criminología sociológica: integración y desintegración
Authors: Zaffaroni Eugenio Raul
Published: November 2020

En general, cada rama del derecho reconoce las funciones de sus respectivas sanciones, sin mayores disidencias entre sus cultores, que pueden disentir sobre su buen o mal uso, pero no sobre la naturaleza y función de ellas. Pero entre los penalistas no existe acuerdo al respecto. Ninguna otra materia jurídica ostenta un abanico de opiniones respecto de la función de su sanción similar a nuestro cuadro de teorías de la pena, por lo que es tiempo de reconocer que se trata de una anomalía jurídica.  Sabemos que el ejercicio del poder punitivo sirve para algo y -si dejamos de lado los libros- intuimos sus muy diferentes y múltiples consecuencias, imposibles de reconocer en totalidad. A veces es posible percibir que, en ciertos conflictos, desempeña alguna de las funciones teorizadas en el cuadro de teorías de la pena, pero en otros sería absurdo asignarle el mismo cometido.  Por eso, cada penalista parte de cómo cree que debiera ser la función y el objeto o fin de la pena y, según esa elección subjetiva, justifica y legitima cierta medida de ejercicio del poder punitivo. Cada penalista dice: la pena debería cumplir esta función y, por ende, la legitimo en la medida en que la cumpla y construyo mi teoría jurídica (sistema) a partir de esta premisa.
Los derechos humanos como herramienta de disputa de comunidades indígenas y organizaciones campesinas frente al Estado paraguayo
Authors: Olguin Valerio
Published: November 2020

En general, este artículo describe un estudio que analizó la viabilidad del uso del derecho y los derechos humanos como herramienta de resistencia y transformación social de comunidades indígenas y organizaciones campesinas de Paraguay a través de un estudio de casos. Es un estudio con perspectiva cualitativa, que, mediante el análisis de los repertorios jurídicos utilizados por los movimientos sociales, campesinos e indígenas, también examinó los factores que inciden para que estas hagan uso del uso del derecho y los derechos humanos como herramienta de resistencia, lo que finalmente permitió identificar los principales obstáculos y límites para garantizar los derechos humanos de estas comunidades y organizaciones del país. Entre los principales resultados se señalan la posibilidad del cambio normativo y la reparación social asumidos como posibles oportunidades políticas que podrían impulsar y expandir los derechos de la población indígena-campesina en el país, siempre y cuando exista un ambiente político e institucional que lo favorezca, y, además se cuente con las estructuras de soportes suficientemente capaces de sostener este tipo de procesos.
Un breve análisis en torno al uso de los tipos omisivos y la necesaria incorporación de la perspectiva de género en la aplicación de la dogmática penal
Authors: Tale Yael Zygielman
Published: November 2020

El texto se propone complejizar desde una perspectiva crítica, el trato que los juzgadores dan a los delitos omisivos, cuando las que resultan imputadas son mujeres que se apartan de lo que consideran “un buen rol de madre”. En estos supuestos bajo la apariencia del uso dogmático de la teoría, las sentencias recurren a argumentos derivados de la propia moral y en el análisis no tienen en consideración la historia de vida y la situación personal de estas mujeres.
El valor de la producción científica y del paper para ingresar a la carrera de investigador del CONICET
Authors: Cano María Eugenia , Chuchuy Ailen , Unzurrunzaga Carolina
Published: November 2020

En este trabajo se analiza la valoración que se realiza de la producción científica y tecnológica de postulantes a la Carrera de Investigador Científico (CIC) del Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) de Argentina, en la categoría inicial, denominada Investigador Asistente. En particular se discuten los criterios de evaluación explicitados para el ingreso a dicha carrera, en sus diferentes modalidades y áreas del conocimiento, que fueron difundidos por CONICET en las convocatorias 2018 y 2019, los cuales fueron categorizados con fines comparativos para identificar el valor relativo asignado en cada área a la producción científica. Además, a fin de analizar cómo se aplican en las distintas subcomisiones estos criterios generales, se tuvieron en cuenta cuestiones observadas en dictámenes recibidos por postulantes. Para finalizar, se presentan una serie de propuestas que se considera contribuirían a descentrar el lugar del paper como factor central en la evaluación.
Integrando a agricultura urbana e periurbana em políticas de planejamento urbano
Authors: Alves Deise de Oliveira , Oliveira Letícia de
Published: November 2020

O rápido crescimento das populações urbanas nos países em desenvolvimento, torna-se impreterível a incorporação da agricultura urbana e periurbana ao planejamento urbano, a partir de políticas de desenvolvimento agrícola e urbano. O estudo teve como objetivo apontar as políticas que dificultam e que favorecem o desenvolvimento da agricultura urbana e periurbana. Para isso, realizou-se uma análise bibliométrica e em seguida, aplicou-se o método PRISMA para a análise sistemática. Os resultados evidenciaram que as cidades possuem políticas de uso da terra, zoneamento de proteção, financiamentos, aluguéis temporários ou doações de terras, método de preservação ambiental e um meio de promover a saúde pública. Entretanto, existem cidades com zoneamento restritivo, políticas proibitivas, regulações mal definidas, restrições de recursos, terras com preços elevados e atividade informal. Conclui-se que a agricultura urbana e periurbana depende de políticas públicas de planejamento urbano do uso das terras agrícolas, políticas de incentivo para produção e consumo.
Palavras-chave: Cidades. Governo. Políticas Públicas. Produção de Alimentos.
Introduction: Hybrid journalism? Making sense of the field’s dissolving boundaries
Authors: Porlezza Colin , Di Salvo Philip
Published: November 2020

In the last couple of years, hybridity has become a buzzword in journalism studies. Hybridity has often been used to describe ongoing transformations in journalism. In this sense, the increasing use of hybridity in the discipline can be seen as an answer, as Witschge, Anderson, Domingo and Hermida (2019, p. 652) declare, “to rising complexity in both journalism practice and scholarship”. At the same time, however, the use of the concept has itself become an object of scholarly debate: while some reject the notion as an undercomplex “catch-all” concept, others believe in its heuristic and analytical prowess. This debate is reinforced by the multiple connotations attributed to the notion, and how the term is used in positive (“a capacity for growth”; Stross, 1999, p. 257) or negative (“diluted version of [the] antecedents”; Chadwick, 2013, p. 14) senses. Either way, hybridity’s success in journalism studies certainly reflects an emancipation from conventional journalism theory, and as a call to develop “new conceptualizations, terminology, and vocabulary” (Witschge et al., 2019, p. 652) in order to grasp the current transformations in journalism – and the different forms of journalism that go beyond traditional understandings and definitions of journalism.
Examining Student Motivation to Use a Gamified System in an Immunology and Immunization Training Course
Authors: Barber Connie , Stavroulaki Konstantina , Santanello Catherine
Published: November 2020

Background: Gamification is the process of adding game elements into classroom activities to encourage student participation and motivation. Classcraft® is a gamified learning system designed to integrate easily with normal classroom activities and to enhance collaboration and teamwork.
Educational activity and setting: This study explored the use of the Classcraft® system in an Immunology and Immunization Training course, specifically examining students’ motivation to use the system and potential impacts on their motivation. 
Findings: Results showed that value and enjoyment motivated students to use Classcraft®. Furthermore, the ease of use of the system positively impacted students’ enjoyment of the system. Students’ choice regarding how much they were required to engage with the system positively impacted the value and enjoyment that they experienced with the system.
Summary: Students’ demonstrated motivation to use Classcraft® provides a foundation for further research into the use of gamified learning systems within pharmacy classrooms. Research is needed to understand if use of a gamified learning system positively impacts learning outcomes.
ASIAVR: Asian Studies Virtual Reality Game a Learning Tool
Authors:   Information Technology Department, Northern Bukidnon Community College, Gumonan Kenn Migan Vincent , Fabregas Aleta ,   College of Computer and Information Sciences, Polytechnic University of the Philippines
Published: November 2020

Purpose–The study aims to develop an application that will serve as an alternative learning tool for learning Asian Studies. The delivery of lessons into a virtual reality game dependson the pace of students. The developed application comprises several more features that enable users to get valuable information from an immersive environment.Method–The researchers used Rapid Application Development (RAD) in developing the application. It follows phases such as requirement planning, user design, construction, and cutover. Two sets of questionnaires were developed, one for the teachers and another for the students. Then, testing and evaluation were conducted through purposive sampling to select the respondents.Results–The application was overall rated as 3.56 which is verbally interpreted as very good. The result was based on the system evaluation using ISO 9126 in terms of functionality, usability, content, reliability, and performance. 476Conclusion–The developed application meets the objectives to provide an alternative learning tool for learning Asian Studies. The application is well commended and accepted by the end-users to provide an interactive and immersive environment for students to learn at their own pace. Recommendations–Further enhancement of the audio, gameplay, and graphics of the tool. Schools should take into consideration the adoption of the Asian Studies Virtual Reality as a good alternative tool for their teachers and students to teach and learn Asian Studies. The use of more 3D objects relevant to the given information to enhance game experience may be considered.A databank for the quiz questions that will be loaded into the game should also be considered.Research Implications–The integration of modern technology in education has been a vital part of the learning process, especially when technological resources are available. Development and adaptation of this application will promote an alternative way of independent learning among students and will give them a better understanding of Asian Studies at their own pace.
Partnerships in Building a Culture of Reading in South Africa: The case of Nal’ibali
Authors: Mubaiwa Denise
Published: November 2020

For many years, literacy experts have been concerned about the culture of reading in South Africa. As a result, many reading initiatives have been started in the country. Nal’ibali (isiXhosa for “it starts with a story”) is one such initiative that was started in 2012. This study aims to highlight the way in which Nal’ibali used partnership to significantly influence the culture of reading in South Africa by reaching out to over 159 191 children through reading clubs and 63 per cent of the South African population through media campaigns and initiatives. This qualitative study extracted data from the Nal’ibali’s monitoring and evaluation reports and campaign marketing documentation and internal evaluations to identify the way in which Nal’ibali is creating a culture of reading in South Africa and its impact. It was established that through partnerships, Nal’ibali is able to create the conditions that the campaign believes are important to create a culture of reading in South Africa. These partners include local community members, businesses, government, churches, libraries, and the media. Having seen the impact the Nal’ibali model has had on the people that the campaign reached, it was concluded that if South Africa is to become a reading nation, government and civil society should continue to partner in its literacy initiatives.
Caries burden and suitability for atraumatic restorative treatment among schoolchildren in Indonesia
Authors: Adyatmaka Irene , Patel Jilen
Published: November 2020

Objectives:

Dental caries remains among the most prevalent chronic conditions in childhood and remains highly prevalent among schoolchildren in Indonesia. Globally, atraumatic restorative treatment (ART) has been used to good effect in the management of carious lesions among high-risk cohorts, particularly in challenging environments. However, in settings, where labor, time, facilities, and materials are particularly limited, strategic triaging of teeth suitable for ART restorations may be valuable to better direct public health expenditure. Therefore, this study aims to (i) describe the prevalence of dental caries among Indonesian schoolchildren and (ii) evaluate the proportion of lesions indicated for ART.

Materials and Methods:

A cross-sectional cohort study of elementary schoolchildren from West Java, Indonesia, was examined and categorized according to Hellman’s dental development stages (Groups 1–4 corresponding to the early mixed dentition through to complete permanent dentition). Descriptive statistics and proportional analysis were conducted with the following variables being evaluated: Teeth with early caries (EC), late/advanced caries (LC), recurrent caries (RC), and total caries experience (TC = EC+ART+LC+RC). In evaluating the suitability for ART, additional variables of ART indicated carious lesions (ART) and lower molars with lesions indicated for ART (LM) were assessed.

Results:

A total of 437 children ranging from 8 to 14 years of age were examined. Out of 8882 teeth examined, 996 had active carious lesions and only 57 had received satisfactory restorative treatment. Children in Hellman’s Group 1 stage of development had the highest prevalence of EC (62%) and ART indicated caries (32%). Meanwhile, older children in Group 4 experienced the highest portion of advanced caries (15%). The proportion of lower molars indicated for ART was 87%, 76%, 70%, and 67% in Groups 1–4, respectively.

Conclusion:

Indonesian schoolchildren face a high burden of untreated dental caries from a young age. The younger the developmental stage, the higher the prevalence of early and ART-indicated lesions with the majority being found in lower permanent molars. Although ART and preventive strategies show the highest potential in the early mixed dentition, they alone cannot completely meet the dental needs of populations such as this where the severity and disease burden are extremely high.
Effects of statins as local drug delivery agents in treating chronic periodontitis and their antimicrobial effects using polymerase chain reaction
Authors: Singh Ritunja , Singh Gangesh B. , Gupta Soumya , Agrawal Anil
Published: November 2020

Objectives:

The aim of the study was to evaluate the anti-inflammatory effect of statin medication in chronic periodontitis patients and to compare the change in periodontal probing depth and clinical attachment level using 1.2% atorvastatin (ATV) gel and scaling and root planning (SRP) compared to SRP alone.

Materials and Methods:

This study was carried out on a sample size of 40 patients with equal male and female ratio between the age group of 40–60 years having chronic periodontitis with a minimum of 20 teeth that were selected for the study. Bilateral quadrants were selected and a split mouth study was conducted. Supragingival scaling was carried out in each patient in one long appointment. The patient was then recalled after 1 week for subgingival SRP. Root planing was carried out in two consecutive visits. Left side of the mouth on the 1st day followed by right side of the mouth on the next day. On the 2nd day, after completion of the root planning, followed by placement of 1.2% ATV gel and finally the Coe Pak was placed in one quadrant which was called the test site. In the other quadrant which was called control site placebo gel was placed and the treated site was covered by the Coe Pak. The recording of clinical parameters (plaque index [PI], gingival index [GI], probing pocket depth, and clinical attachment loss) was done at baseline, 1 month and 3 months. The selected site was sampled for subgingival microflora. The data obtained were subjected to statistical analysis. One-way ANOVA, Tukey’s HSD test, and student t-test were used for intergroup and intragroup comparison.

Results:

In our study, when intergroup comparison of mean value for PI at baseline, 1 month and 3 months was found to clinically insignificant for control and test groups, while for GI, periodontal pocket depth, and clinical attachment level it was found insignificant at baseline while significant at 1 and 3 months. Similarly, when comparison was made for microbial count it was found clinically insignificant between control and test group at baseline, while significant was noted at 3-month interval.

Conclusion:

Our study evaluated the anti-inflammatory, osteoconductive and antimicrobial effects of atorvastatin giving significant reduction in PI, GI, PPD and gain in CAL along with significant decrease in the microbial load.
Knowledge, attitude, and practices of biomedical waste management among clinical dental students
Authors: Khubchandani Kanika , Devi M Kaviya , Gunasekaran Subhathraa , Yeturu Sravan Kumar , Ramanarayanan Venkitachalam
Published: November 2020

Objectives:

The health-care sector generates enormous amount of biomedical waste (BMW) and dental waste forms a subset of this hazardous waste. It is, therefore, imperative for the upcoming dental health professionals to be aware of the hazards related to improper waste management and the existing rules and regulations for the same. To gauge the gaps in knowledge and find ways to rectify the same, the aim of this study was to assess the knowledge, attitude, and practice of biomedical waste management among dental students.

Materials and Methods:

A cross-sectional study was carried out in a dental teaching hospital, wherein a pre-validated and tested, structured closed-ended questionnaire was adopted and given to the clinical students of dentistry. The responses were self-recorded by the participants after which statistical analysis was carried out using Chi-square test to compare the levels of knowledge, attitude, and practice among the study groups.

Results:

Out of 168 participants, 97% agreed that waste needs to be segregated but 70% were unaware of the legislations regarding BMW management. About half of the participants across all groups gave incorrect responses regarding correct disposal of various types of wastes. Only 10.1% of students correctly disposed mercury. Among the study groups, postgraduate students fared better than house surgeons and students. More than 90% of students believed that they required additional training in BMW management.

Conclusion:

An overall positive attitude was seen among all students toward safe management of BMW. However, their knowledge and practice toward the same calls for attention on the part of educational institutions in providing continuous educational programs and monitoring the correct disposal of wastes. This was validated by the fact that increase in educational qualification showed better performance toward this subject.
Role of coronary artery calcium score in risk prediction and therapy guidance of asymptomatic individuals
Authors: Simon Judit , Száraz Lili , Merkely Béla , Maurovich-Horvat Pál
Published: November 2020

Coronary CT angiography (CCTA) has emerged as a gatekeeper to rule out coronary artery disease (CAD), due to its high sensitivity and negative predictive value. Prior to CCTA a native calcium screening scan is acquired, which provides additional information about the coronary artery anatomy and cardiovascular risk prediction by measuring coronary artery calcification (CAC). Based on large population-based and cohort studies, zero CAC score is linked to low probability of cardiovascular events in the future. Moreover, zero CAC score is superior in the discrimination and risk reclassification when compared with other cardiovascular risk factors. CAC score can also help to identify those who are less likely to benefit from statin pharmacotherapy. Since CAC score has an important role in risk stratification and it is a cheap and widely accessible non-invasive imaging modality, the major guidelines have already incorporated CAC score for risk prediction and therapy guiding. However, these guidelines give slightly different recommendations. Therefore, this review aimed to introduce the CAC measurement and to summarize the prognostic role of CAC scoring in individualized risk prediction and guiding preventative therapies.
Statinadherencia akut koszorúér-esemény után
Authors: Simon Attila , Kósa István , Vassányi István , Andrássy Gábor , Erdei Ferenc , Kohut László , Páder Katalin , Simon Éva , Szász Károly , Veress Gábor , Tiringer István
Published: November 2020

Akut koszorúér-események után a gyógyszeres szekunder prevenció alapvető eszköze a hatékony koleszterincsökkentés, amelynek alapkészítményei a HMG-CoA-reduktáz-inhibitorok (statinok). Bár a gyógyszercsalád jelentősen képes mérsékelni az éresemények ismétlődését, a betegek kitartása a statinterápiához közismerten gyenge, ami részben indokolhatja a célértékek el nem érését, a magas vaszkuláris morbiditást és mortalitást az ismerten érbetegek között. Célok: Vizsgálatunkban arra a kérdésre keresünk választ, hogy különböző akut koszorúér-esemény után rehabilitációs kezelésben részesült betegek statinszedési szokásai hogyan alakulnak az önbevallás, illetve a receptkiváltások alapján. Betegek és módszer: Prospektív, multicentrikus vizsgálatunkban 7 centrumban bevont 445 beteg (kor 61,3±8,7 év, 70,1% férfi) adatait elemeztük, akinél egyaránt rendelkezésre álltak az önbevallásos és receptkiváltáson alapuló egyéves követési adatok. Közülük 289-en szívinfarktus (AMI-csoport), 53-an perkután revaszkularizáció (PCI-csoport), 103-an szívizom-revaszkularizációs műtét (ACBG-csoport) után kerültek bevonásra. Egy évvel később a betegek kérdőívben, vagy telefoninterjú során nyilatkoztak gyógyszeres kezelésükről. Rendelkezésünkre álltak a receptkiváltás adatai, amely alapján meghatároztuk a gyógyszeradherenciát és -perzisztenciát. Eredmények: Kiinduláskor szignifikánsan kevesebb beteg részesült statinkezelésben az ACBG-műtött csoportban (egész csoport: 95,1%; AMI: 96,9%; PCI: 96,2%; ACBG: 89,3%, a csoportok között jelentős az eltérés, p<0,01). Ugyanakkor itt volt legmagasabb az LDL-koleszterin szintje (egész csoport: 1,98±0,79; AMI: 1,97±0,81; PCI: 1,74±0,68 ACBG: 2,12±0,75 mmol/l, a csoportok között jelentős az eltérés, p<0,01). Egy évvel később az egész populációban a betegek 83,6%-a volt statinkezelésen önbevallás alapján (AMI: 85,0%, PCI: 84,3%, ACBG: 79,4%), nem találtunk szignifikáns különbséget a csoportok között. A receptkiváltáson alapuló adatok lényegesen rosszabb képet mutattak (a jó adherenciával bíró betegek aránya az egész csoportban: 53,8%, AMI: 57,1%, PCI: 51,9%, ACBG: 44,8%, különbség nem szignifikáns). Többváltozós lineáris regressziós modellben szintén egyik változó sem volt a statinadherencia önálló prognosztikus tényezője. A betegek perzisztenciája is az AMI-csoportban volt a legjobb. Következtetések: Bár akut koszorúér-betegség utáni rehabilitációban részt vevő betegek nagy arányban részesülnek statinkezelésben, ACBG-műtét utáni betegeknél már kiinduláskor is kisebb arányban van jelen statinkezelés. Egy évvel az esemény után nagyon alacsony a jó adherenciájú betegek aránya.
AV-nodális reentry tachycardia ablációs kezelése utáni aránytalan sinuscsomó-tachycardia
Authors: Borbola József , Földesi Csaba , Kardos Attila , Som Zoltán
Published: November 2020

Az elmúlt években 17 betegnél (15 nő, 2 férfi; életkor: 29,6±6,7 év) észleltünk AV-nodális reentry tachycardia (AVNRT) ablációs kezelése után fellépő ún. aránytalan sinuscsomó-tachycardia tünetcsoport (perzisztáló palpitáció, inadekvát sinustachycardia – IST) nyugalomban vagy kis fizikai/pszichés terhelésre, 24 órás Holter-monitoros EKG-felvételen a sinusfrekvencia napi átlaga ≥90/min) kialakulását. Mindegyik betegnél előzőleg típusos AVNRT miatt ún. lassúpálya rádiófrekvenciás abláció történt, 5 betegnél redo beavatkozás formájában. A perzisztáló panaszok (EHRA életminőségi score: 2,7±0,4) az ablációs kezelés után röviddel alakultak ki (3,3±0,9 hét). A palpitációs panaszok néhány hónapon belül (5±1,5 hónap) spontán vagy béta-blokkoló (bisoprolol 2×5 mg/nap) kezelésre megszűntek. A posztablációs betegcsoportban laboratóriumi screening (vérkép, TSH), EKG, echo-vizsgálatok, terheléses EKG, 24 órás Holter-monitoros és transztelefonos EKG-megfigyelések történtek. A Holter-monitoros EKG-megfigyelés kapcsán IST-re jellemző eltérést minimum-maximum-(átlagos) sinusfrekvencia/min 24 óra alatt: 56±5–160±8 (93±7)/min tapasztaltunk. Ezek az értékek béta-blokkoló kezelésre normalizálódtak: 52±5–125±8 (75+8)/min (p<0,0001), a betegek életminőségi jellemzői is jelentősen javultak (EHRA-score: 1,1±0,2; p<0,0001). Sem a Holter-monitorozás, sem a terheléses EKG kapcsán rekurrens AVNRT nem volt. A transztelefonos EKG a panaszok alatt mindenkinél sinustachycardiás epizódokat rögzített. A pitvari posteroseptalis területen történő rádiófrekvenciás ablációs kezelés után nem ritka az ún. posztablációs IST kialakulása. Ez a ritmuszavar-entitás az irodalmi adatok alapján a sinuscsomót beidegző paraszimpatikus idegrostok tranziens sérülésével, denervációjával hozható összefüggésbe. Eseteinkben redo abláció után gyakrabban észleltük. A posztablációs Holter-monitoros EKG-megfigyelés, de különösen a transztelefonos EKG alkalmazása fontos nemcsak az AVNRT rekurrencia kizárására, hanem az IST igazolására is.
Sport, iszkémiás szívbetegséggel
Authors: Szelid Zsolt
Published: November 2020

Az iszkémiás szívbetegség fokozott hirtelen szívhalál kockázatot jelenthet, amit az intenzív sportaktivitás fokozhat. Szívizom-iszkémia mellett, valamint szívinfarktust követően az intenzív sporthoz való visszatérés lehetséges, azonban a terhelhetőség orvosi megítélése során számos tényezőt kell figyelembe venni. Iszkémiás szívbetegség gyanúja esetén elsősorban a betegségrizikó mérlegelése, igazolt koszorúsér-betegség esetén pedig az akut koronáriaesemény rizikójának megítélése az elsődleges feladat. A versenysporttal kapcsolatos rizikómeghatározások lényeges eleme a teljes kifáradásig történő terheléses tesztek elvégzése, valamint koronária-CT-angiográfia-vizsgálat elvégzése, ami a betegek számára a biztonságos „return-to-sport” lehetőségét jelentheti.
Viscoelastic Phase Patterning in Artificial Protein Hydrogels
Authors: Rapp Peter , Silverman Bradley
Published: November 2020

Viscoelastic forces can affect the dynamics of pattern formation during phase separation in polymeric materials. We programmed an artificial protein hydrogel to undergo viscoelastic phase separation above a critical temperature. Highly dynamic phase patterns that coarsened under the influence of viscoelastic stresses spontaneously emerged in these gels. Local oxidative crosslinking promoted by mild photobleaching could be used to initiate phase separation locally, enabling the creation of non-equilibrium patterns that evolved under the influence of surface tension and viscoelastic stresses to yield dynamic structures of controlled size and shape.
The Effect of Aluminium Addition on Solid Solution Strengthening in CoCrFeMnNi High Entropy Alloy: Experiment and Modelling
Authors: Kumar Jitesh , Gurao Nilesh P , Biswas Krishanu
Published: November 2020

The effect of aluminium addition to the Cantor alloy in the composition regime of 0.25-5 atomic percent on solid solution strengthening of single phase HEA was investigated using experiments and constitutive modeling. The continuous increase in yield and tensile strength without significant change in ductility is observed for the alloys characterized by almost similar grain sizes (~100 μm) with increasing aluminium content. The constitute modeling of the strengthening has been performed using traditional as well as recently developed models for solid solution strengthening. The constitutive modeling indicated significant contribution of solid solution strengthening due to addition of Al having relatively larger size (̴12%) than the size of elements in the Cantor alloy leading to severe local lattice distortion. The experimental yield strength could be best explained on the basis of large apparent distortion volume of Al atom acting as a stronger barrier to dislocation motion based on the Varvenne model.
H2S Stability of Metal-Organic Frameworks: A Computational Assessment
Authors: Lyu Pengbo , Maurin Guillaume
Published: November 2020

The H2S stability of a range of MOFs was systematically assessed by first-principle calculations. The most likely degradation mechanism was first determined and we identified the rate constant of the degradation reaction as a reliable descriptor for characterizing the H2S stability of MOFs. A qualitative H2S stability ranking was thus established for the list of investigated materials. Elemental structure-stability relationships were further envisaged considering several variables including the nature of the linkers and their grafted functional groups, the pore size, the nature of metal sites and the presence/nature of coordinatively unsaturated sites. This knowledge enabled the anticipation of the H2S stability of one prototypical MOF, e.g. MIL-91(Ti), which has been previously proposed as a good candidate for CO2 capture. This computational strategy enables an accurate and easy handling assessment of the H2S stability of MOFs and offers a solid alternative to experimental characterizations that require the manipulation of a highly toxic and corrosive molecule.
Tapping the Unexplored Potential of Marine Fungi and Edible Mushrooms for in Silico Screening of Anti-Viral Bioactive Compounds Against SARS-CoV-2 for Rapid Development of Nutraceuticals
Authors: Srivastav Amit Kumar , Jaiswal Jyoti , Kumar Umesh
Published: November 2020

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2) affects human respiratory function that causes COVID-19 disease. COVID-19 has spread rapidly all over the world and became a pandemic within no time. Therefore, it is the need of hour to screen potential lead candidates from natural resources like edible mushrooms and marine fungi. These natural resources are very less explored till now and known to be the source for many medicinal compounds with several health benefits. These medicinal compounds can be easily exploited for the faster development of nutraceuticals for controlling SARS-CoV-2 infections. Our in-silico research suggests that bioactive compounds originating from mushroom and marine fungi shows strong potential to interact with ACE2 receptor or main protease of SARS-CoV-2, showing the inhibition activity towards the enzymatic protease. We performed a series of in silico studies for the validation of our results, which includes Molecular docking, drug likeness property investigation by Swiss ADME tools, MD simulation, and thermodynamically stable free binding energy calculation. Overall, these results suggest that Ganodermadiol and Heliantriol F bioactive compounds originating from edible mushroom has strong potential to be developed as low-cost nutraceutical against SARS-CoV-2 viral infection. The drug candidate isolated from marine fungi and edible mushroom are highly unexplored for the development of potential alternative drug against SARS-CoV-2 virus with minimum side effects. That is why we decided to screen some active metabolites from the marine fungi and mushrooms, which offer some encouraging results. Though our in-silico studies of these compounds are showing a promising result against SARS-CoV-2 main protease and ACE2 receptor binding domain, the effectiveness of these bioactive compounds should be further validated by proper clinical trials.
In situ X-ray Diffraction Investigation of the Crystallisation of Perfluorinated Ce(IV)-based Metal-Organic Frameworks with UiO-66 and MIL-140 architectures
Authors: Shearan Stephen , Jacobsen Jannick , Costantino Ferdinando , D’Amato Roberto , Novikov Dmitri , Stock Norbert , Andreoli Enrico , Taddei Marco
Published: November 2020

We report on the results of a thorough in situ synchrotron powder X-ray diffraction study of the crystallisation in aqueous medium of two recently discovered perfluorinated Ce(IV)-based metal-organic frameworks (MOFs), analogues of the already well investigated Zr(IV)-based UiO-66 and MIL-140A, namely, F4_UiO-66(Ce) and F4_MIL-140A(Ce). The two MOFs were originally obtained in pure form in similar conditions, using ammonium cerium nitrate and tetrafluoroterephthalic acid as building blocks, and small variations of the reaction parameters were found to yield mixed phases. Here, we investigate the crystallisation of these compounds in situ in a wide range of conditions, varying parameters such as temperature, amount of the protonation modulator nitric acid (HNO3) and amount of the coordination modulator acetic acid (AcOH). When only HNO3 is present in the reaction environment, F4_MIL-140A(Ce) is obtained as a pure phase. Heating preferentially accelerates nucleation, which becomes rate determining below 57 °C, whereas the modulator influences nucleation and crystal growth to a similar extent. Upon addition of AcOH to the system, alongside HNO3, mixed-phased products, consisting of F4_MIL-140A(Ce) and F4_UiO-66(Ce), are obtained. In these conditions, F4_UiO-66(Ce) is always formed faster and no interconversion between the two phases occurs. In the case of F4_UiO-66(Ce), crystal growth is always the rate determining step. An increase in the amount of HNO3 slows down both nucleation and growth rates for F4_MIL-140A(Ce), whereas nucleation is mainly affected for F4_UiO-66(Ce). In addition, a higher amount HNO3 favours the formation of F4_MIL-140A(Ce). Similarly, increasing the amount of AcOH leads to slowing down of the nucleation and growth rate, but favours the formation of F4_UiO-66(Ce). The pure F4_UiO-66(Ce) phase could also be obtained when using larger amounts of AcOH in the presence of minimal HNO3. Based on these in situ results, a new optimised route to achieving a pure, high quality F4_MIL-140A(Ce) phase in mild conditions (60 °C, 1 h) is also identified.
Facile Preparation of a Binderless Hierarchical Beta Zeolite in Shaped Form and with Improved Acidity for Catalysis
Authors: Liu Jiaxu , Zhang Zhenmei , Liu Chunyan , Vilé Gianvito , Xiong Guang , He Ning
Published: November 2020

The synthesis of a technical hierarchical nanosized zeolite catalysts without growth modifiers and binders remains a major challenge in catalysis. Herein, we report a new synthetic approach to directly produce hierarchical nanosized Beta zeolites in technical form, without any binders in the final material. The synthesis consists of two steps, where a Beta zeolite powder is first shaped using tetraethyl orthosilicate; the extrude is then recrystallized at high temperature in the presence of tetraethylammonium hydroxide solution. This transforms the SiO2 binders into zeolite framework. A variety of characterization methods were applied to unlock structure-properties relationships of the materials and demostrate their catalytic functionality. We believe that this work opens avenues for the advanced manufacturing of hierarchical zeolite materials in shaped form, and will find useful applications in catalysis and materials science.
Anti-microbial activity of seed extract of Cucumis sativus L., Carica papaya L. and Annona squamosa L.
Authors: Abirami S  , Antony V Samrot  , Emilin Renitta R  , Kanchana S  , Noorudeen M B  , Yamunadevi K  , Dhiva S  , Saigeetha S
Published: November 2020

In recent days, threat related to infectious and antibiotic-resistant pathogens are increasing widely, and this created an urge to search for an alternative way of producing drugs. The sources selected for the production of drugs must have some attributes like readily available, available in bulk quantities, easy processing and containing less or negligible toxic effects. Herbal medications and drugs derived from medicinal plants may serve as a smart and an alternate way. In this study, ethanolic seed extracts have been used from three readily available plants like Cucumis sativus  L., Carica papaya  L., Annona squamosa  L. The antibacterial activity of ethanolic seed extracts was performed against the pathogens present in the pus sample using agar disc diffusion method. It was found that the ethanolic seed extracts of Cucumis sativus L. were found to have a maximum zone of inhibition of 14 mm at conc., of 900 µg against S. aureus, Carica papaya L. was found to have maximum inhibition of 13mm at conc., of 900µg against S. aureus and Annona squamosa showed negligible resistance to all pus pathogens. From the various bioactive compounds present in the plants, an efficient drug can be manufactured, and it may find a great place in the pharmaceutical industry.
“I don’t have an address”: Housing instability and domestic violence in help-seeking calls to a support service
Authors: Weatherall Ann , Tennent Emma
Published: November 2020

Increasing recognition of the long-term negative impacts of gendered violence has led to the establishment of a variety of social support services. Feminist research has examined the barriers that prevent women from accessing these services and the problems women report getting the help they need. However, little is known about what happens in situ when women interact with support services. This paper is a novel empirical investigation of naturalistic social interactions where women seek help with problems resulting from violence at home. We used conversation analysis to examine how problems of housing instability and help-seeking unfolded in recorded telephone calls to a victim support service. We found that the routine institutional practice of asking for an address posed interactional trouble for women who were seeking to leave violence, had left a violent home, or were homeless as a result of violence. When answers could not be provided, callers’ responses included disclosures of violence or challenges to the meanings of address. Our findings point to an interactional burden that women confront in institutional interactions. We suggest institutions should carefully consider how routine practices such as asking for an address might pose unintended problems for service users in vulnerable circumstances.
Kedaulatan dan Yurisdiksi Negara terhadap Pulau Buatan dalam Perspektif UNCLOS 1982
Authors: Ronaboyd Irfa
Published: November 2020

The provisions in UNCLOS 1982 are also historical representations in following developments and demands of the times to solve various problems of sea use. A number of principles in marine law instruments were reaffirmed, in addition to the new principles or provisions added to UNCLOS 1982 in order to resolve future and future maritime territorial disputes. Nevertheless, there are a number of things that have not been regulated in detail by UNCLOS 1982, for example artificial islands.The artificial island discourse was again a concern by various parties, especially international law experts. The debate surfaced after China in the South China Sea built five artificial islands and military installations on it. The artificial island is built on the reefs of the Spartly islands, the South China Sea. Apart from the Chinese polemic in building artificial islands in disputed areas, basically every coastal country has exclusive jurisdiction to build artificial islands within the Exclusive Economic Zone (EEZ). Even under international law all countries have the freedom to build artificial islands on the high seas
Penyelesaian Kerugian pada Pendapatan Negara melalui Pengungkapan Ketidakbenaran (Suatu Kajian Hukum Doktrinal dalam Sistem Perpajakan)
Authors: Arifki Nindi Achid
Published: November 2020

Losses on state revenues are clauses that are explicitly stated in general provisions and taxation procedures. at the praxis level, arrangements relating to the content and limitation of loss clauses on state revenues cannot be found and expressly stated in the construction of tax law or in the realm of state financial law construction. Using the method of doctrinal legal research and by utilizing secondary data and the hermeneutic approach, this paper aims to examine the discourse of settlement of losses in state revenues through disclosure of untruthfulness in juridical construction of state financial law and regulations in the field of taxation. The conclusion obtained is that there are no strict norms that regulate the content and limits of loss clauses on state revenues, so that the discourse of settlement of losses on state revenues through disclosure of untruth can be legitimate and possible.
A secondary case of meningococcal disease in an ambulance worker, Berkshire, November 2007
Authors: Petsas A , Sharma A , Aghadiuno O , Abid M , Paranthaman K
Published: November 2020

Secondary cases of meningococcal disease among healthcare workers are rare and avoidable. In this report, we describe a secondary infection in a healthcare worker who did not have significant contact with respiratory secretions of the index case.
HIV testing in Europe: from policies to effectiveness some highlights from the meeting
Authors: Eurosurveillance editorial team
Published: November 2020

It has been estimated that 30 percent of people living with HIV in the European Union (EU) are unaware of their infection [1]. As undiagnosed patients cannot benefit from early treatment and may unknowingly transmit HIV to others, this situation poses a major challenge in the fight against the HIV/AIDS epidemic.
Epidemic intelligence in the European Union: strengthening the ties
Authors: Coulombier D
Published: November 2020

Public health surveillance remains the cornerstone of the detection of health threats requiring public health action. Two articles in this issue of Eurosurveillance refer to the challenges of epidemic intelligence activities in European Union Member States.