bluuebunny/crossref_metadata_2025 huggingface dataset:
"IMPACT OF INFORMATION TECHNOLOGY ON BANKING BUSINESS, AN ANALYTICAL STUDY"
Authors: Dr. Rekachand Ganpat Gongale
Published: March 2024

Due to the Information Technology known in Banking business, mainly using internet, extranet and intranet etc. in Banking, through electronics, Banking and their customers complete all their transactions using computer and do all the records of paperless transaction in computer.

All the computers in the country or the world are connected by internet so any person in the country can contact the bank from any location, pay, withdraw, transfer money, tasks are completed on time, there is more transparency in the transaction, valuable time of customers is not wasted, employee on Work stress is reduced, search farm inspection is faster, less staff and more profit etc.

Information technology has made the banking process faster and more reliable than ever before and the maintenance and retrieval of documents and records has become faster and easier. Technology creates competition in competitive industries and provides better customer service. That is, information technology has had a positive effect on the lucrative business.

Overall, information technology has made the financial services more convenient, efficient and personalized and has led to significant growth and progress in the banking industry.
भारतीय संस्कृति में राष्ट्रीय एकता व इसकी विशेषताएँः एक विमर्श
Authors: रत्नेश पाण्डेय
Published: March 2024

भारतीय संस्कृति में राष्ट्रीय एकता व इसकी विशेषताएँः एक विमर्श
THE WOMEN’S MOVEMENT FOR EQUITABLE DEMOCRATIC SOCIETY IN INDIA
Authors: Dr. V. Ramesh Babu  , Dr. V. M. Raja  Sekhar
Published: March 2024

India is the largest democratic country with 143 crores of population and the 95 crores of voters  participating  the biggest elections in the world. Women population in India are the half of the total population, but in all walks of life women don’t have the equal opportunities and justice though they are enshrined in the Indian Constitution. Indian women had the wider experience of  conducting movement  in  the freedom movement. After Constitution came into force women had to start their movement to secure their rights. If women could have achieved their movement then they  will get equal opportunities and justice in the society, that will be an equitable democratic society. It is observed that to achieve that that aim of the movement women should have followed the democratic  way of fighting in which-----  respecting the views of others,  acting cooperatively, arriving the decisions through discussions, respecting equality, respecting the rights of others, and tolerating the views of others. This should be the attitude and perspective of the  entire women movement. Recently the Indian Parliament passed the 33% of Political Reservation bill , women movement should utilize this  constitutional amendment for their better life, then only they will able to enjoy their constitutional guarantees of liberty, equality, justice, fraternity and political empowerment. Women movement will have to get the aimed equitable democratic society through Constitutional methods. We  followed the Historical and analytical research methods while pursuing this paper, we invited the further research in pursuing area.
IMPACT OF THE NEW EDUCATION POLICY ON JOB SATISFACTION AMONG COLLEGE TEACHERS
Authors: Debashis Dutta  , Dr. Babita Chaudhary
Published: March 2024

The purpose of the study was to explore the job satisfaction of college teachers in the era of the New Education Policy. The education landscape is ever-evolving, and policy changes play a pivotal role in shaping the experiences of educators. The implementation of a new education policy marks a significant shift in the way academic institutions operate. As educational systems transform, such as the implementation of a new policy, it is imperative to investigate the effects on the individuals directly involved in its execution. In this context, college teachers play a pivotal role in shaping the educational landscape, and their job satisfaction is crucial for fostering a positive learning environment. This study aims to investigate the impact of the recently introduced education policy on job satisfaction among college teachers and to assess the specific ways in which the new education policy influences various aspects of job satisfaction among college teachers, including workload, professional development opportunities, teaching methodologies, and overall job contentment. Understanding the impact of the new education policy on job satisfaction is crucial for fostering a positive and conducive working environment for college teachers.

The findings of this research are expected to contribute valuable insights to educational policymakers, administrators, and educators, facilitating informed decision-making to enhance the overall quality of education and the professional lives of college teachers. As educational institutions continue to adapt to the evolving landscape, this study provides a timely exploration of the intricate relationship between policy changes and the job satisfaction of those at the forefront of the teaching profession.
SECURING THE FUTURE OF EDUCATION: QUANTUM ENCRYPTION AND BEYOND – AN EXAMINATION OF CUTTING-EDGE SECURITY TECHNOLOGIES
Authors: Shyja K. G.  , Mehthab N  , Shabna K. V.
Published: March 2024

Education plays a pivotal role in the overall development of individuals as well as the society. A holistic approach to education involves examinations, various forms of assessment, and continuous evaluation to provide a comprehensive view of a student's abilities and knowledge. The digital era's transformational consequences are always welcomed in the dynamic field of education. Today, many regional, national, and worldwide tests, evaluation methods, and learning platforms are being administered online. Without a doubt, in a short while, technology will control the entire educational system. Nonetheless, even with the most sophisticated technological approaches to security and encryption, preserving the integrity of online exams is becoming increasingly difficult. Quantum encryption may be able to help in this situation. The application of quantum encryption, along with its theoretical underpinnings and principles, is the focus of this study. By safeguarding against eavesdropping, it lays the groundwork for future examination administration that will ensure the safest and most secure means of transmitting question papers.
ROLE OF ARTIFICIAL INTELLIGENCE IN ENHANCING EDUCATION AND SOCIAL LIFE
Authors: Dr. Mohammadi Shaikh  , Shaikh Summaiya Naznin
Published: March 2024

This paper seeks to understand approach and pattern of Artificial Intelligence (Al). It examines the contemporary approaches to Artificial Intelligence.

Artificial Intelligence (Al)is a branch of Science which deals in development of modern machines, which can find solutions to complex problems in human. Artificial intelligence basically works on human intelligence characteristics and algorithms so that machine can behave like human.
RECONSTRUCTION OF NATION THROUGH EMPOWERMENT OF WOMEN
Authors: Babila Chauhan Sakhuja  , Anchita Sakhuja
Published: March 2024

Women's empowerment can be characterized to advancing women's healthy self-awareness worth, their capacity to decide their own decisions, and their entitlement to impact social change for them and others. Women empowerment - a basic common liberty that is additionally key to accomplishing a more prosperous world. Women's empowerment and advancing women's privileges have arisen as a piece of a significant worldwide development and is proceeding to kick off something new. Days like International Women's Empowerment Day are additionally acquiring momentum. But regardless of a lot of progress, women and young ladies keep on confronting separation and viciousness in all aspects of the world. This paper talks about how empowering women will gain a colossal effect on the headway of any country. The paper illuminates how any country can be reconstructed by empowering women.
THE SUBALTERN AND FEMINIST VOICES IN INDIRA GOSWAMI’S SHORT STORY “SANSKAAR’’
Authors: Dipraj Banik
Published: March 2024

The events in "Sanskaar" by Indira Goswami take place in Pitambor's rural environment, creating a tapestry of hardships, disputes, and unexpected salvation. This journal explores the complexities of caste, gender, and cultural standards in an effort to dig into the subaltern and feminist aspects present in the story. While Pitambor struggles with his personal issues, the narrative reveals Damayanti's strength as a widow defying social norms. This diary seeks to highlight the feminist undertones that influence the characters' fates and unearth the subaltern voices inside the story through a close examination of their interactions.
TECHNOLOGIES OF TOMORROW: A GEOPOLITICAL GATEWAY TO A MULTI-POLAR WORLD ORDER AND INDIA’S OPPORTUNITIES AND CHALLENGES IN IT
Authors: Ms. Shiwani Yadav
Published: March 2024

This paper argues how technology will serve as a key gateway into a world with several poles. It further discusses the opportunities in favor of India to guarantee its position in the emerging power structure. And, the various obstacles that India has on its path to be a stable and developed economy. With the unchallenged hegemony enjoyed by The United States wearing thin by the day, increasing vulnerabilities sprout in the contemporary world order backed by its supremacy across domains. Technological advancement has consistently been a distinguishing factor in determining geopolitical power dynamics through the ages. It has historically paved the way for military superiority and political hegemony. The US's dominance following the Cold War is waning. There’s a concurrent rise of the Eastern wing and the Global South as a whole.  Emerging technologies like Quantum Computing, Artificial Intelligence, 5G, and Blockchain could further expedite the process. Rising powers are competing to deploy these across various potentially disruptive fields, set to usher us into a multi-polar world order. The rebalancing forces, concentrated mainly in Asia, are challenging axioms, redefining conventional notions, and renegotiating terms of engagement in a world more globally interconnected than ever. China and India make two re-emerging civilization giants with contrasting state apparatuses and value systems but similar objectives of securing for themselves a more assertive, sovereign, and determined place in the Global order. India in its 76th year of Independence finds itself amidst a host of opportunities and challenges unleashed by the unraveling of the established order, supply-chain disruptions, and a new round of geostrategic churn in its proximal theaters.
LESSING AND THE NEW WOMAN
Authors: Dr. Bhagwant Kour
Published: March 2024

Doris Lessing’s play Each his Own Wilderness presents us with the image of the ‘New Woman’. Myra and Milly are single independent women(Myra a widow and Milly a divorcee) who fight hard to find their place in the world. They have a voice and a career. Having no husbands to cater to, these women can lead a comparatively freer life and are vocal about their needs and wants. However motherhood is a bondage that they cannot free themselves of easily. Hence though husbands are absent, patriarchy is not. Through motherhood, patriarchy continues the structure in which female is kept in the service of male and hence motherhood becomes oppressive.
UNDERSTANDING THE MOLECULAR BASIS OF JN.1
Authors: Dr. Raghavendra Rao M. V.  , Dr. Vijaykumar Chennamchetty  , Dr. Pavani G.  , Dr. Manick Dass  , Dr. Srilatha Basetty  , Dr. Rajkumar Kudari  , Dr. Mahendra Kumar Verma  , Dr. Abdur Rahman  , Dr. P. Jaganmohan Rao
Published: March 2024

COVID-19 JN.1,subvariant, was initially identified in Luxembourg and is believed to have a connection to the Pirola variant (BA 2.86), which is considered a derivative of the Omicron subvariant.The new Omicron variant of SARS-cov-2 speeding around the world may bring another wave of chaos. It is like walking on a tightrope. The earth is brimming with viruses. The lungs are the paramount respiratory organs. Covid 19 sub variant JN.1 detected in 79 years old Kerala woman.It has been detected in Kerala amid surveillance led by Indian SARS-CoV-2 Genomic Consortium (INSACOG).Originally part of lineage BA.2.86, JN.1 is now recognized as a distinct variant of interest by the WHO. Reassuringly, WHO states that current vaccines remain effective against severe disease and death caused by JN.1 and other circulating COVID-19 variants. In early December, the CDC, reported that the JN.1 subvariant constitutes an estimated 15% to 29% of cases in the United States, as per the agency's most recent projections. According to the CDC, JN.1 was initially identified in the United States in September. Additionally, China reported seven infections of the COVID subvariant.
A STUDY OF CUSTOMERS SATISFACTION LEVEL IN ALMORA ZILA SAHKARI BANK LTD.
Authors: Dr. Vivek Kumar Arya  , Dr. Shalini Thapa
Published: March 2024

Customer satisfaction is one of the most important factors in banking business. When it comes to co-operative banks, customers satisfaction level differentiates one bank from another, thus measuring customer satisfaction is exceedingly important. This research paper is an attempt to examine the current level of customer satisfaction in Almora Zila Sahkari Bank Ltd. For this study, descriptive research design is used which is mainly based on primary data collected through the questionnaire. Information is gathered from the different customers of Almora Zila Sahkari Bank Ltd. In this study the researcher understand various aspects regarding the customer satisfaction in the services offered by AZSB Ltd. 150 customers are used as sample for the study. To assess the customer’s satisfaction level, 5 point Likert’s scale has been used. It is observed that the overall perceptions of customers towards the services of AZSB Ltd. rated “above average” satisfaction level (above 3 to below 4).
Proses Terjadinya Adaptasi Ruang di Rumah Tinggal yang Mengubah Fungsi Ruang Rumah Menjadi Ruang Usaha di Jogokaryan, Kota Yogyakarta
Authors: Kristiyani Wahyu Desy , Damanik Imelda Irmawati
Published: March 2024

Title: The Process of Space Adaptation in Residential Houses that Change the Function of Home Space into Business Space in Jogokaryan, Yogyakarta City

Home Base Enterprises (HBE) is one of the businesses run by many Indonesians. HBE is a type of business carried out in residential homes, so adaptation is needed to meet the needs of space that changes its function as a business space. This research aims to discover the process of changing the space function because of the house owner's adaptation. The method used in this study is descriptive qualitative with simple random sampling of data collection. Of the four selected samplings, the result is that the process of forming space in HBE is based on cultural, physiological, and morphological adaptations. For the production business, the method uses an adaptation of extending space, while the trading business uses an adaptation of sharing space.
Greening the UAE workforce: Can green human resource management and domestic environmental regulations support green innovation at the workplace?
Authors: AlNaqbi Eman , Mohd Shamsudin Faridahwati
Published: March 2024

This study aimed to investigate how legal regulations mediated the relationship between green human resource management (GHRM) practices and innovation in organizations. It assessed the impact of GHRM on employees’ commitment to environmental sustainability through training and communication. Additionally, the study examined how employees’ environmental values influenced their innovative behavior within the organizational context. The study used structural equation modeling and multigroup analysis. A survey was conducted among 246 employees aged 20-59 years and employed in transportation (Etihad Airways and Dubai Silicon Oasis Authority), tourism (Burj Khalifa, Jumeirah Group, Sheraton, and Hilton), energy and utilities (Dubai Electricity and Water Authority, Masdar City, and Abu Dhabi National Oil Company), development (Department of Urban Planning and Municipalities, Research Technology and Innovation Parks, and National Health Authority), and agriculture (Agthia Group, Badia Farms, Al Dahra, and Al Rawabi) sectors. GHRM practices significantly affected employees’ attitudes and behaviors, fostering their engagement in sustainability initiatives. Environmentally conscious employees favored creative and sustainable work practices. Domestic legal regulations and organizational practices enhanced the innovative response. Moreover, younger pro-environmentalist employees demonstrated increased receptivity to GHRM practices compared to older employees. In conclusion, GHRM contributed to economic diversification in the UAE by fostering a workforce skilled in sustainable practices, attracting talent to support emerging industries, aligning with economic reforms, and enhancing the overall reputation of the country as a hub for sustainable and diversified economic activities.
EDUCAÇÃO A DISTÂNCIA NO BRASIL: UM PANORAMA HISTÓRICO SOBRE OS ÚLTIMOS CINCO ANOS DA MODALIDADE NO PAÍS
Authors: Villela Mafra da Silva Andréa , Valadão Sabrina
Published: March 2024

O trabalho analisa o percentual de cursos no ensino superior no Brasil que oferecem a modalidade de Educação a Distância (EaD), durante a pandemia de SARS-CoV-2. Metodologicamente, utilizamos a pesquisa exploratória e descritiva (Severino, 2007). Para o levantamento dos dados quantitativos e estatísticos utilizamos o Censo da Educação Superior, referentes aos anos de 2017 a 2021. Concluímos que a pandemia contribuiu para o aumento dos cursos em EaD, contudo observamos a influência do incentivo governamental brasileiro para a propagação dessa modalidade no país.
Research on the distributed Clark confluence model based on basic watershed units
Authors: Zhu Junjun , Liu Jingru , Zhou Hui , Che Xuheng
Published: March 2024

Based on the confluence principle, the confluence should represent the aggregate of net rainfall confluences within each distinct basic watershed unit (BWU) of a basin. The BWUs are categorized as V-type and Horseshoe-type based on their shape characteristics and two types of time–area curves of slope convergence have been derived separately. The cascade river convergence is modeled using a lagged linear reservoir, resulting in the development of a distributed CLARK convergence model based on the BWUs of a basin (BWU-DCLARK). The key findings are as follows: (1) The BWU-DCLARK model effectively captures the runoff convergence process and has been successfully applied in the Yanduhe River basin. Modeling results demonstrate high simulation accuracy. (2) The time of slope convergence indicates that the regulatory and storage effects on runoff of BWUs cannot be overlooked. (3) The BWU-DCLARK confluence model not only enables the calculation of flow at the basin outlet but also facilitates the computation of flow at any node along the river chain which is of great significance for hydrological forecasting in un-gauged basins but the application effect will need further verification.
Evaluating consumer insights in water services: perspectives on health benefits, pricing tolerance, and continuous service demand
Authors: Rahman Herawati Zetha , Juniati Atie Tri , Miraj Perdana , Zuna Herry Trisaputra , Plamonia Nicco
Published: March 2024

This study investigates the relationship between consumers and water services, focusing on the global challenge of providing clean and reliable water. Employing structured questionnaires, the research explores customers’ perceived health benefits, willingness to pay (WTP) for potential price increases, and service expectations. The study, primarily quantitative in nature, gathered data from both customers and non-customers of water services. The findings reveal that customers are more likely to recognize health benefits from water services compared to non-customers, emphasizing the role of health perceptions in service acceptance. A significant majority of respondents showed a willingness to accept modest tariff increases. However, this willingness sharply declines as the proposed increase grows, indicating a clear threshold in consumers’ financial flexibility. A strong preference for 24-h water service emerged, underscoring the importance of continuous service in consumer satisfaction. Additionally, factors such as water consistency, cleanliness, and pressure were identified as key determinants of service adoption and satisfaction. These insights are crucial for water service providers and regulators, suggesting the need for a balanced approach to pricing, service quality, and continuity. The study highlights the importance of communication about the health benefits of water services, offering guidance for enhanced customer engagement, service adoption, and retention strategies.
Testing the Significance of Ranked Gene Sets in Genome-wide Transcriptome
Profiling Data Using Weighted Rank Correlation Statistics
Authors: Yao Min , He Hao , Wang Binyu , Huang Xinmiao , Zheng Sunli , Wang Jianwu , Gao Xuejun , Huang Tinghua
Published: March 2024

Background:

Popular gene set enrichment analysis approaches assumed that genes in the
gene set contributed to the statistics equally. However, the genes in the transcription factors (TFs)
derived gene sets, or gene sets constructed by TF targets identified by the ChIP-Seq experiment,
have a rank attribute, as each of these genes have been assigned with a p-value which indicates the
true or false possibilities of the ownerships of the genes belong to the gene sets.

Objective:

Popular gene set enrichment analysis approaches assumed that genes in the
gene set contributed to the statistics equally. However, the genes in the transcription factors (TFs)
derived gene sets, or gene sets constructed by TF targets identified by the ChIP-Seq experiment,
have a rank attribute, as each of these genes have been assigned with a p-value which indicates the
true or false possibilities of the ownerships of the genes belong to the gene sets.

Methods:

A method was proposed by first creating ranked gene sets and gene lists and then applying
weighted Kendall's tau rank correlation statistics to the test. After introducing top-down weights
to the genes in the gene set, a new software called "Flaver" was developed.

Results:

Theoretical properties of the proposed method were established, and its differences over
the GSEA approach were demonstrated when analyzing the transcriptome profiling data across 55
human tissues and 176 human cell-lines. The results indicated that the TFs identified by our method
have higher tendency to be differentially expressed across the tissues analyzed than its competitors.
It significantly outperforms the well-known gene set enrichment analyzing tools, GOStats (9%) and
GSEA (17%), in analyzing well-documented human RNA transcriptome datasets.

Conclusions:

The method is outstanding in detecting gene sets of which the gene ranks were correlated
with the expression levels of the genes in the transcriptome data.
Exploring and Designing Potential Inhibitors of SIRT2 in Natural Products by Artificial Intelligence (AI) and Molecular Dynamics Methods
Authors: Ni Yangyang , Bai Juxia , Zhang Yuqi , Qiao Haoran , Liang Liqun , Wan Junfeng , Zhu Yanyan , Cao Haijing , Li Huiyu , Zhao Qingjie
Published: March 2024

Background:

The histone deacetylase family of proteins, which includes the sirtuins, participates
in a wide range of cellular processes, and is intimately involved in neurodegenerative illnesses.
The research on sirtuins has garnered a lot of interest. However, there are currently no effective
therapeutic drugs.

Methods:

In order to explore the potential inhibitors of SIRTs, we first screened four potential lead
compounds of SIRT2 in Traditional Chinese Medicine (TCM) for nervous disease using the Auto-
Dock Vina method. Then, with Molecular Dynamics (MD) simulation method, we discovered how
these inhibitors from Traditional Chinese herbal medicines affect this protein at the atomic level.

Results and Discussion:

We found hydrophobic interactions between inhibitors and SIRT2 to be
crucial. The small molecules have been found to have strong effect on the residues in the zincbinding
domain, exhibiting relationship with the signaling pathway. Finally, based on the conformational
characteristics and the MD properties of the four potential inhibitors in TCM, we have designed
the new skeleton molecules according to the parameters of binding energy, fingerprint similarity,
3D similarity, and RO5, with AI method using MolAICal software.

Conclusion:

We have proposed the candidate inhibitor of SIRT2. Our research has provided a new
approach that can be used to explore potential inhibitors from TCM. This could potentially pave the
way for the creation of effective medicines.
Breast Cancer Management: The Role of Nutrition, Exercise and Psychosocial Well-being
Authors: Bora Sankar Jyoti , Deka Dhruva Jyoti , Malakar Chinmoy , Kashyap Nancy , Das Bhrigu Kumar
Published: March 2024

Background:

Breast cancer incidence and mortality rates are rising worldwide, which presents
a formidable challenge for women. The advancement of targeted drug therapies offers promising
avenues for treatment, but resource constraints prevent their widespread implementation in advanced
clinical trials, highlighting the need for sustained research funding. Nutritional support is critical
in cancer management, affecting key cancer hallmarks. The anti-inflammatory effects of exercise
and a healthy diet are critical in reducing cancer incidence and tumor growth. A comprehensive approach
to breast cancer treatment requires addressing health challenges and psychological symptoms.

Objective:

In this context, we aim to address modifiable risk factors, including nutrition, physical
activity, and psychosocial factors, which can serve as non-pharmacological adjuncts in reducing
breast cancer risk, incidence, and mortality.

Methods:

This study conducted a thorough literature search on breast cancer, nutrition, physical activity,
psychosocial problems, clinical trial/study, mechanisms, in-vitro and in-vivo. The search was
performed using multiple search engines and the main keywords, and only English publications until
August 2023 were included.

Results:

Nutrition plays a critical role in influencing breast cancer risk, but its exact role needs to be
explored. Diet diversity and exercise are recommended to reduce risk, while psychosocial support is
vital for patient well-being.

Conclusion:

In light of rising global breast cancer challenges, our study underscores the urgent need
for enhanced clinical trial availability, exploration of nutrition-cancer links, and refined psychosocial
interventions to comprehensively address prevention and treatment.
Assessment of Monitoring and Management Practices of
Antipsychotic-Induced Hyperprolactinemia at a Medical City in Riyadh,
Saudi Arabia: A Retrospective Cohort Study
Authors: Hussain Alshabeeb Zahra , Alsuwayni Bashayr , Alshargi Omar , Abdelazeem Ahmed H.
Published: March 2024

Background::

Hyperprolactinemia is a commonly underestimated adverse effect of
antipsychotic medications. There are still no consensus guidelines for the optimal monitoring
and treatment strategies.

Objective::

The aim of the study was to assess the monitoring and treatment practices of antipsychotic-
induced hyperprolactinemia, in addition to the prevalence and risk factors associated with
it.

Methods::

A retrospective cohort observational study was conducted among patients attending
the psychiatric clinics at an academic tertiary hospital in Riyadh, Saudi Arabia, from May 2020
until May 2021, by reviewing each patient’s medical record for up to five years.

Results::

Among the 662 patients, 35 patients (5.3%) and 242 patients (36.6%) had their serum
prolactin levels monitored (at baseline and at follow-up, respectively). The prevalence of hyperprolactinemia
was observed in 212 patients (32%). Only 76 patients (36%) were symptomatic.
Female gender, younger age, and bipolar disorder had a significantly higher risk of developing
hyperprolactinemia. 60% of the confirmed cases received treatment, of which 76 (60%) were
adherent to treatment guidelines. The most common treatment strategies implemented were dose
reduction (42.5%) and aripiprazole augmentation (29.1%).

Conclusion::

It is imperative to conduct a baseline check of prolactin levels before commencing
any antipsychotic therapy. Similarly, routine prolactin level monitoring is recommended regardless
of symptoms in patients treated with antipsychotics with a possible prolactin-raising effect.
Adherence to evidence-based treatment guidelines can improve patient quality of life and therapeutic
compliance.
Oral Candidiasis in Patients with Rheumatoid Arthritis: A Hospital-Based Cohort Study
Authors: Leite da Silva Cristhiane Almeida , Siqueira Gabriela Camarneiro , Fernandes Vander , Volpato Luiz Evaristo Ricci , Shimoya-Bittencourt Walkiria , Borba Alexandre Meireles , Benites Bernar Monteiro , Candido da Silva Ageo Mario
Published: March 2024

Background:

Rheumatoid (RA) arthritis is a chronic autoimmune disease characterized by symmetric polyarthritis and systemic inflammation. Systemic complications due to RA and its treatment may affect oral health.

Objective:

To assess the prevalence and predisposing factors for oral candidiasis in Rheumatoid Arthritis patients treated at a rheumatology referral hospital.

Methods:

This is a longitudinal study of a panel of repeated measures performed on patients attending the Rheumatology and Oral Diagnosis Outpatient Clinic of the General Hospital of Cuiabá. Patients were followed up between 2018 and 2019, with the information recorded in the medical records and subsequently extracted. A generalized estimation equation model was used to assess the association between oral candidiasis and RA.

Results:

In the final model, in crude (bivariate) analysis, the use of prednisone (OR 8.3) and tocilizumab (OR 3.7) were significantly associated with oral candidiasis. In the multivariate generalized estimation equation model, the use of prednisone (OR 9.9) and the presence of hyposalivation in male patients (OR 1.8) were the variables that remained statistically associated with oral candidiasis.

Conclusion:

The use of immunosuppressive drugs and the low rate of salivary flow in male patients increase the risk of oral candidiasis in patients with rheumatoid arthritis, reinforcing the importance of stomatological monitoring, a preventive approach and early diagnosis of this pathology.
A Review on Hydrogels for Smart Drug Delivery Systems and their Mathematical Modelling
Authors: Kalyani Chinnala , Hitashi Prashant , Gupta Deepshikha , Verma Rohit , Raula Manoj , Varshney Gaurav , Gupta Tejendra K .
Published: March 2024

Since the last few decades, smart hydrogels have become a vibrant research
area in biomedical science and engineering. Nowadays, smart hydrogels can
be used in drug delivery systems due to their biocompatibility, physicochemical properties,
and high stability. External factors like temperature, pH, ionic concentration,
light, magnetic fields, electrical fields, and chemicals can alter smart hydrogels'
chemical and biological characteristics. Furthermore, there have been sophisticated
advancements in polymer science that combine two or more responsive mechanisms
to create polymers with multiple responsive properties. In this review article, we discussed
the recent advancements in the field of smart hydrogels, their preparation
methods, important properties, and multifunctional applications. The FDA approval
for clinical purposes is also given for specific commercial applications. Various
mathematical models have also been discussed to simulate and optimize the drug release
behavior from hydrogels and to provide valuable insight into the drug release
profile over time. The latest advancement in the field of stimuli-responsive drugloaded
hydrogels and the contributions of the researchers in this field are also highlighted.
Finally, the advantages and disadvantages of smart hydrogels and their future
challenges are also discussed.
An integrated approach in the management of Cardiovascular Diseases
Authors: Pratibha Lokhande  , Babita Sharma  , Nitin Ujjaliya
Published: March 2024

Cardiovascular diseases (CVDs) are the leading cause of death globally. According to WHO an estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to heart attack and stroke. India has one of the highest burdens of cardiovascular disease worldwide. The annual number of deaths from CVD in India is projected to rise from 2.26 million (1990) to 4.77 million (2020). The rate of incidence of cardiac disorders is almost doubled in Indian population which is an alarming fact.  Cardiovascular Disease is largely the product of interactions of modifiable risk factors like changing lifestyles, bad eating habits and rapidly evolving socio-economic determinants like access to healthcare. There is a need of developing an integrative approach which conceptualizes a unique blend of different systems to bring the balance of body, mind and spirit for perfect health. Ayurveda holds the breakthrough to the key challenges that the India and in turn the world is facing in present era in cardiac care. Various scattered literature can be brought together and a clinical cardiology in Ayurveda can be given to modern society. Present paper is an effort towards Integrative approach for the management of CVDs.
A literary review article on Agnikarma in Kamala
Authors: Khandelwal Anisha , Giri V. Rajneesh  , Bhakta S.
Published: March 2024

Jaundice is defined as a yellowish discoloration of skin, mucous membrane and sclera due to the deposition of bile pigment (bilirubin). It can be classified as pre-hepatic, hepatic and post hepatic jaundice. The causes of various forms of Jaundice are either acquired or congenital. The incidence of jaundice in India is 2.37-3.15 per 1000 population. Varied reasons result in jaundice. Some of them are medically managed whereas some require surgical interventions. The underlying causative factors and clinical manifestations in such conditions are similar to Kamala described in Ayurveda. Various treatment protocols have been mentioned by various Acharya in their respective Samhita. One among them is a handbook for an Ayurvedic physician from Andhra Pradesh, written by Basavaraju named as Basavarajiyam where he has mentioned Agnikarma in Kamala Vyadhi which is a unique practice that might help for early recovery of patients. Another famous book on Viddha and Agnikarma Chikitsa by Dr.R.B. Gogate from Maharashtra also mentions about similar kind of treatment. By considering all these, the present article is aimed at understanding the textual references of Agnikarma in Kamala.
Partial Fistulotomy followed by Kshara application and Ksharasutra Ligation in Fistula-in-ano - Multiple approaches in a Single Case
Authors: Srinivasa NV  , Shilpa PN
Published: March 2024

Bhagandhara is one of the common ailments pertaining to Guda and it is mentioned under the heading of Ashtomahagada (eight major diseases). According to Acharya Susahruta, ‘Bhagandhara’ starts as deep-seated pidika (boil) surrounding Guda (anus) within two Angulas, producing fever and pain. In contemporary science it is compared to fistula-in-ano. Fistula-in-ano is a track lined by granulation tissue and communicating two epithelial lined surfaces which opens deeply in the anal canal or rectum and superficially on the skin around the anus. In modern medical science various treatment modalities has been explained but they are having its own merits and demerits.  Ksharasutra is a medicated thread, indicated in ano-rectal disorders particularly in the management of Bhagandhara. In plane Kshrasutra the required time for cut through and healing of wound is more, so patients are mentally disturbed with this disease. Hence to minimize the required time, multiple interventions along with Ksharasutra is opted. In this case report, a patient of fistula- in-ano having 9cm at posterior aspect of anal canal was treated with multiple approaches which are partial fistulotomy, Kshara application and Ksharasutra ligation for remaining part of tract. Regular dressing was done with Jatyadi Ghrita for the partial fistulotomy wound and old Ksharasutra was changed with a new one by rail-road method on every week for the remaining part of fistulous tract. The unit cutting time (UCT) was measured and noted at every week. This case was cured completely within 7 weeks. Hence study concluded that the long fistula cases can be treated with multiple interventions along with Ksharasutra.
A Novel Ayurvedic treatment - Arthrothermia® for Osteoarthritis
Authors: Shah Prerak , Kagrana Dhruti
Published: March 2024

Purpose: The purpose of this study was to report promising data revealed by a novel Ayurvedic treatment; Arthothermia® for patients with knee osteoarthritis (OA). Method: We enrolled 30 patients with OA who received Arthothermia® treatment. The Knee injury and Osteoarthritis Outcome Score (KOOS) was used to evaluate the treatment outcome. The five subscales of KOOS: Pain, Other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL) were scored separately. The KOOS data was calculated for the 30 patients before and after Arthothermia® treatment. Results: The KOOS before Arthothermia® ranged from 3.37 to 31.3. The KOOS was significantly improved after Arthothermia® and it ranged from 83.67 to 98.53. The difference in KOOS between before and after Arthothermia® treatment was calculated for the 30 patients as a group (unpaired t-test) as well as for each patient individually (paired t-test). The difference in KOOS was highly significant (p<0.0001) for both; unpaired and paired t-test analysis. Conclusion: The present study documented that the “Arthothermia®” – a unique Ayurveda treatment approach (combination of alkaline cautery and indirect micro thermal cautery) brought significant changes in KOOS in the OA patients in very short time duration. The promising data hold a ray of hope for better management of OA and needs wide explorations to bring magnificent outcome for patients suffering with OA.
Sicad: Smart Information System For Village Administration As An Empowering Ngadiluwih Village Kediri In Improving Community Services
Authors:   Department of Statistics, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Astuti Ani Budi
Published: March 2024

The Ngadiluwih Village Government, Kediri Regency, East Java Province also really needs an Android-based application so that the reach of access is wide in an effort to digitize villages to improve village administration services online. The purpose of this community service activity is to build and develop the Ngadiluwih Village Government Smart Information System application, which is abbreviated as Ngadiluwih SICAD in the context of empowering Ngadiluwih Village in an effort to improve online village administration services to the community. The socialization, implementation, and assistance were also carried out to village officials and the community regarding the Ngadiluwih SICAD application product. The results of this activity show that the Ngadiluwih SICAD that has been built is in accordance with the expectations and needs of Ngadiluwih Village and the community with 14 types of letter facilities.
Peningkatan Nilai Tambah Simplisa Jahe Merah Subgrade Di Bumdesma Sari Bumi, Kecamatan Pule, Kabupaten Trenggalek
Authors:   Fakultas Teknologi Pertanian, Universitas Brawijaya, Santoso Imam
Published: March 2024

Badan Usaha Milik Desa Bersama (BUMDesma) Sari Bumi merupakan badan usaha yang bertujuan untuk meningkatkan kerjasama antar desa dalam usaha ekonomi serta untuk meningkatkan pendapatan masyarakat desa. Kegiatan utama BUMDesma adalah pengolahan rimpang (jahe merah, kunyit, temulawak) menjadi simplisia. Simplisia jahe merah dikelompokkan menjadi 3 kriteria grade (A, B, dan C). Simplisia dengan standar yang memenuhi kualitas grade A dan grade B dipasarkan ke beberapa mitra yang bekerjasama, dan simplisa jahe merah subgrade atau grade C akan dikembalikan ke gudang produksi. Masa simpan simplisia jahe merah di gudang hanya sekitar 1 tahun, sehingga membutuhkan upaya pengelolaan agar tidak rusak. Kegiatan Pengabdian Kepada Masyarakat bertujuan untuk melakukan inovasi pengolahan simplisia subgrade menjadi produk minuman jahe merah instan celup. Nilai tambah yang dihasilkan setelah dilakukan pengolahan simplisia subgrade menjadi minuman jahe merah celup adalah 54%. Hal tersebut menunjukkan bahwa pengolahan simplisia subgrade mampu memberikan nilai tambah yang besar.
Fostering empowerment and building capacities of rural women through community-based agroindustry: A case study in Donowarih Village, Indonesia
Authors:   aculty of Agricultural Technology, Universitas Brawijaya,, Suhartini Sri
Published: March 2024

Donowarih village, located in Malang Regency, East Java, Indonesia, is closed to the Universitas Brawijaya’s Educational Forest (known as UB Forest). The village has various potential local commodities such as orange fruits and batik. During harvesting season, the price of orange fruits declined, and inadequate storage system has led to a rapid deterioration of orange fruits. Furthermore, various problems faced by the community, such as poverty and lack of knowledge/skills, are becoming the major challenges to be tackled. On the other hand, orange fruits and batik are potential to be diversified into high value-added products, which can be done through the introduction of post-harvesting technology and trainings for skills improvement. Furthermore, the Indonesian Government program of one village one product (OVOP) is becoming key drivers to any community engagement program in Indonesia.
Virtual reality simulators for temporal bone dissection: overcoming limitations of previous models
Authors: Batsaikhan Temuulen , Seo Young Joon
Published: March 2024

Temporal bone dissection is a critical skill for otolaryngology trainees: however, it is challenging to master due to the complex anatomy and limited exposure to cadaveric specimens. The aim of this review was to develop and evaluate a novel virtual reality (VR) simulator for temporal bone dissection, addressing the limitations of previous simulators reported in the literature. A comprehensive literature search was conducted in the PubMed, Embase, and Cochrane Library databases from inception to September 2022. The search was limited to studies that evaluated the effectiveness of VR simulators for temporal bone dissection. The quality of the included studies was assessed using the Cochrane Risk of Bias Tool. The results showed that VR simulators can significantly improve temporal bone dissection skills, including anatomical knowledge, instrument handling, and surgical performance. Compared to traditional training methods, VR simulation was associated with faster learning curves, better retention of skills, and greater confidence among trainees. However, some limitations of current VR models were identified, including the lack of haptic feedback, limited realism, and short duration of practice. VR simulators are a valuable adjunct to traditional methods for temporal bone dissection training. The recently developed VR simulator addressed the limitations of previous simulators and demonstrated its potential to enhance the training of clinicians in temporal bone dissection. Future directions for research include further validation of the simulator and exploration of its potential for use in clinical settings.
Programa para aulas con estudiantes sordos: Construcción de profesionales chilenos y colombianos
Authors: Muñoz Karina , Sastre Gonzalez Carmen , Enríquez Lozano Carlos , Sánchez Bravo Alejandra
Published: March 2024

La comunicación y el aprendizaje son un referente espontáneo dentro de los procesos educativos de los seres humanos, en los que se incluyen programas para estudiantes sordos. El artículo tiene como objetivo describir los componentes necesarios de un programa para un aula con estudiantes sordos y sordas. Con un enfoque de corte cualitativo, un diseño fenomenológico, se recogió información a través de grupos de discusión con la participación e interacción de profesionales chilenos y colombianos. Los participantes fueron 44, entre ellos: fonoaudiólogos, profesores de sordos, co-educadores/modelos lingüísticos, intérpretes de lengua de señas chilena y colombiana. Los resultados establecieron 3 categorías: perfil profesional, estrategias comunicativas-cognitivas y elementos fortalecedores. Las conclusiones van orientadas a la importancia de considerar elementos articuladores como el trabajo colaborativo y la gestión pedagógica en el desarrollo del trabajo profesional de un programa educativo para un aula con estudiantes sordos.
A tríade universidade, escola e profissão na formação docente: Considerações sobre a verticalização nos Institutos Federais de Educação, Ciência e Tecnologia
Authors: Neuhold Roberta dos Reis , Pozzer Márcio Rogério Olivato
Published: March 2024

Este artigo contextualiza os cursos de formação inicial de professores na arquitetura institucional de uma política federal brasileira e sinaliza seu potencial de reduzir as distâncias entre universidade, escola e profissão. Sublinhando a urgência de serem constituídas novas institucionalidades que concretizem os processos de formação de professores, António Nóvoa propõe a criação de “casas comuns” capazes de estabelecer ligações orgânicas entre o ambiente acadêmico, o cotidiano escolar e a profissão docente. No Brasil, uma política de abrangência nacional dialoga diretamente com essa proposta. Pouco estudada, começou a ser implementada em 2008, nos Institutos Federais de Educação, Ciência e Tecnologia e tem na verticalização do ensino um dos fundamentos de sua organização político-pedagógica, ofertando cursos de diferentes níveis, incluindo o ensino secundário e as licenciaturas. O quadro docente, por seu turno, com remuneração e plano de carreira equiparados aos professores universitários, leciona, na mesma instituição, tanto na educação básica quanto no ensino superior, atuando como professor pesquisador e formador de professores. É a essa experiência que o presente artigo se reporta. A partir de um estudo qualitativo de enfoque descritivo, recupera os antecedentes da política pública discutindo a fundação dessa nova institucionalidade em um cenário de escassez de professores. Direciona a atenção, então, à inovação institucional propiciada pelo modelo de verticalização, acenando para a sua potencial contribuição na constituição do que Nóvoa nomeia como o triângulo da formação docente, em cujos vértices estariam a escola, a universidade e a profissão. Ao final, problematiza os desafios para a consolidação da proposta.
Intervenção em estratégias de aprendizagem: Uma proposta de formação de professores em serviço
Authors: Santos Deivid Alex dos , Alliprandini Paula Mariza Zedu
Published: March 2024

Este estudo teve por objetivo analisar os efeitos de uma intervenção desenvolvida no formato de uma sobreposição curricular relacionada ao ensino de estratégias de aprendizagem aos professores do Ensino Médio de uma escola pública estadual do Paraná/Brasil. Participaram da pesquisa até à conclusão 14 professores. Os professores participaram da intervenção no formato híbrido que durou 5 meses e foi composta por 17 sessões de intervenção, totalizando 50 horas. A pesquisa seguiu um delineamento quase-experimental cumprindo as etapas de pré-teste, intervenção e pós-teste. Na intervenção foram ensinadas aos professores estratégias de aprendizagem cognitivas, metacognitiva, de recursos internos e contextuais. Os resultados apontaram diferenças estatisticamente significantes ao comparar o pré e pós-teste para as subescalas de autorregulação: cognitiva e metacognitiva, de recursos internos e contextuais e autorregulação total da escala. Ressalta-se a necessidade de mais estudos com professores em formação inicial ou continuada, pois eles desempenham um importante papel na formação de seus alunos, bem como com outros participantes, níveis escolares, culturas e contextos.