bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise das imprecisões diagnósticas na conduta da otite média aguda: uma revisão integrativa da literatura
Authors: Vieira Maria Carolina Menck , Bhering Carlos Alberto , Belini Augusto Mariano , Vieira Pedro Luis Menck , Bergamo Sarah Gomes
Published: October 2022

Objetivo: Compreender as dificuldades no diagnóstico e tratamento da otite média aguda e buscar entender os perigos decorrentes da imprecisão deste diagnóstico no atendimento das crianças. Métodos: Este estudo realizou pesquisas nas plataformas National Library of Medicine (PubMed) e SciELO, priorizando trabalhos dos últimos 10 anos, 2010 a 2020. O aumento da delimitação temporal nas bases de dados foi necessário devido à dificuldade de se encontrar artigos recentes sobre o tema exposto. Sendo selecionados 23 artigos. Os descritores foram “Otitis media”, “Diagnosis,” “Otorhinolaryngology” e “Drug Resistance”. Resultados: Baseado nesses dados evidenciou-se a existência de uma imprecisão diagnóstica e terapêutica na OMA das crianças. Esta conclusão é suportada diretamente pelas análises de 5 autores e indiretamente pela análise dos demais aqui analisados. Todos afirmam que: a OMA é de difícil diagnóstico; é uma doença comum e natural nas crianças e autolimitada na maioria das vezes; há um uso excessivo e desnecessário de antibióticos; há uma imprecisão diagnóstica generalizada dos profissionais de saúde. Considerações finais: Os profissionais estão aptos para identificar e tratar adequadamente a doença, mas os cursos de formação ainda precisam se estruturar melhor para evitar imprecisões diagnosticas no futuro e se conscientizarem sobre o uso indiscriminado de antibióticos.
A relevância do profissional de enfermagem no aleitamento humano: uma revisão integrativa
Authors: Canejo Stephany Paula da Silva , Barros Milene Melo de , Santana Jéssica Ariel Rodrigues de , Dantas Bruna Caroline Lins , Silva Bruna Alexandra Menezes da , Silva Jakelyne Rafaela Lima da , Santana Marilúcia do Nascimento , Lira Luenny Karoline de , Didier Tamires Evelyn Bahia , Bezerra Thainara Estelita de Vasconcellos
Published: October 2022

Objetivo: Identificar, analisar e discutir os estudos sobre a importância do profissional de Enfermagem no processo do aleitamento humano. Métodos: Revisão integrativa de artigos buscados entre março e junho de 2021 nas bases eletrônicas Scientific Electronic Library online (SciELO), Literatura Latino-Americana e do Caribe em ciências da saúde (Lilacs) e PubMed. Resultados: Foram encontrados 23.489 trabalhos sem aplicabilidade de critérios de inclusão, 129 estudos a partir dos critérios de inclusão e exclusão e foram utilizados 5 entre estes. As publicações datam dos anos de 2017 a 2021 e foram realizadas no Brasil e no idioma português. Os achados apontam a importância do profissional de enfermagem como catalisador da promoção da saúde no processo de amamentação, em todos os níveis de atenção à saúde, sobretudo na educação em saúde. Considerações finais: Os profissionais de enfermagem são fundamentais na preservação da amamentação e, portanto, devem estar propriamente habilitados e capacitados para que falhas na assistência à saúde sejam evitadas, especialmente no pré-natal e na educação em saúde durante o ciclo gravídico.
Caregiving strain is associated with cardiac autonomic imbalance in primary oncology caregivers: A cross-sectional analytical study
Authors: Pant Arjun , Rajasegaran Rajalakshmi , Dubashi Biswajit , Jagadesan Pandjatcharam , Ganapathy Sachit
Published: October 2022

Objectives:

Oncology caregivers often endure a significant amount of psychosocial stress while going through the experience of caregiving for their dependents. Exposure to chronic stress disrupts the cardiac autonomic balance and increases the risk of cardiovascular events. There is a paucity of research on the association between caregiving strain and cardiac autonomic status of primary oncology caregivers. This study aimed to assess the cardiac autonomic balance and its association with the levels of perceived strain and quality of life (QOL) of primary oncology caregivers.

Materials and Methods:

Forty-six individuals (30 males and 16 females) who have been primary caregivers of patients under the treatment for cancer at the Regional Cancer Centre over the past 3 months–1 year were recruited in this cross-sectional study. Cardiac autonomic status was assessed by heart rate variability (HRV) technique. The level of strain perceived and QOL of the study participants were assessed using the Modified Caregiver Strain Index (MCSI) and Caregiver QOL-Cancer (CQOL-C) questionnaires, respectively. Comparison of study parameters based on MCSI scores (low strain vs. moderate-high strain) was done using the Independent Student’s t-test. Spearman rank correlation coefficient test was performed to assess the correlation between sympathovagal balance (Low frequency [LF]/high frequency [HF]) and other study parameters. Multiple linear regression analysis was performed to predict the LF/HF ratio with independent variables MCSI score and CQOL-C score. P < 0.05 was considered statistically significant.

Results:

Significantly high blood pressure, LF power, LF nu (LF normalised units) and LF/HF ratio were observed among caregivers with moderate-to-high caregiving strain as compared to those with low strain levels, while significantly low HF nu (HF normalised units) and CQOL-C scores were noted among the moderate-to-high caregiving strain subgroup as compared to the low caregiving strain subgroup. LF/HF ratio revealed a significant positive correlation with the level of caregiving strain (r = 0.563, P < 0.001) and a significant negative correlation with the QOL (r = −0.489, P = 0.001) of caregivers. However, on regression analysis, the level of caregiving strain was found to be a significant predictor of autonomic dysfunction unlike the caregivers’ QOL.

Conclusion:

Increased caregiving strain is associated with cardiac autonomic imbalance in primary oncology caregivers.
Effect of dual blockade of renin-angiotensin system on renal nephrin and vascular endothelial growth factor – A expression in diabetic-hypertensive rats
Authors: Mobarak Asmaa Hussien Elsayed , Sayed Nesrine Salah El Dine El , Maklad Yousreya Aly Aly , Kenawy Sanaa Abdel-Baky
Published: October 2022

Objectives:

The effects of early renin-angiotensin system (RAS) blockade using angiotensin-converting enzyme (ACE) inhibitor lisinopril and/or angiotensin receptor blocker valsartan on renal nephrin and vascular endothelial growth factor (VEGF)-A gene expression were investigated in diabetic-hypertensive rats.

Materials and Methods:

Diabetes and hypertension were induced in adult Wistar rats using streptozotocin (45 mg/kg, i.p.) and Nω-nitro-L-arginine methyl ester (60 mg/kg/12 h) for 4 consecutive days. Experimental animals were allocated into six groups (n = 6): normal control, diabetic control, diabetic-hypertensive control and lisinopril-, valsartan- and combination-treated diabetic-hypertensive groups (5 mg/kg/drug/day, p.o., for 21 days). Blood glucose, blood pressure, body weight, kidney weight to body weight ratio, serum albumin, creatinine, total protein and urea were measured and recorded every week. Nephrin and VEGF-A gene expression were measured using real-time polymerase chain reaction. Renal nephrin protein was measured using ELISA as well as nephrin immunostaining.

Results:

Blood pressure was significantly decreased by all treatments (P ≤ 0.05). All treatments normalised serum albumin and urea. Serum creatinine significantly decreased, while total protein significantly increased (P ≤ 0.05). Nephrin gene expression had a non-significant decrease in diabetic-hypertensive rats, yet it was statistically increased with individual treatments (P ≤ 0.05) and normalised with combined treatment. Renal nephrin protein significantly decreased in diabetic-hypertensive rats, normalised by lisinopril and significantly increased by valsartan and combined treatments (P ≤ 0.05). VEGF-A expression significantly increased in diabetic-hypertensive rats and significantly decreased with lisinopril and valsartan monotherapy and normalised with combined treatment (P ≤ 0.05). Immunostaining of nephrin also showed an obvious increase in the case of combined treatment.

Conclusion:

Early dual blockade of RAS in diabetic-hypertensive rats protected against renal damage and improved renal nephrin and VEGF-A gene expression as well as renal nephrin protein expression.
EEG microstates in resting condition in young indians
Authors: Tayade Prashant , Kaur Simran , Muthukrishnan Suriya Prakash , Sharma Ratna , Saini Gaurav
Published: October 2022

Objectives:

The map topography analysis gives an idea of temporal dynamics of electric fields, which is reference independent, making the results unambiguous. These topographic maps remain stable for 80 to 100 milliseconds, abruptly shifting to a new topographic map configuration and remains stable in that state are called the ‘functional microstates’ as described by Lehmann et al (1987). There has been no study done in the resting state eye closed and eye open conditions showing the microstate maps in healthy Indian subjects in resting eyes open and resting eyes closed condition using 128 channel EEG. So our study aim was to assess the microstates in resting eyes closed and eyes open condition. And to compare the microstate parameters such as mean duration, global explained variance (GEV) and time coverage between eyes closed and eyes open condition.

Materials and Methods:

A cross-sectional and observational study on 20 indian subjects (Mean age- 26.65 and (SD) - 2.78 years) was done on resting eyes closed and eyes open conditions. After EEG acquisition using 128 channel EEG machine, EEG was preprocessed and microstate analysis using CARTOOL software was performed on the EEG data.

Results:

After microstate analysis four maps topography were obtained. There was statistically non-significant difference observed in microstate maps between resting eyes closed and resting eyes open condition for the all parameters i.e. mean duration, time coverage and GEV.

Conclusion:

Our findings suggests that, both eyes closed and eyes open conditions were similar to each other in terms of stability and predominance of Maps.
A study of changing trends in consumer preferences and perspectives towards health-care services during the pandemic
Authors: Medimpudi Srikanth , Medimpudi Lucklin , Ayyagari Lakshmana Rao , Araveti Jeswanth , Kadiri Mahesh
Published: October 2022

Objectives:

The novel coronavirus disease 2019 (COVID-19) pandemic has caused a turmoil in the health-care delivery system and challenged consumers’ sense of well-being. This study examines the evolving consumer expectations and explores the key interventions that health-care providers can employ to increase engagement with consumers and prepare organisations to cope with post-pandemic challenges.

Materials and Methods:

We conducted a cross-sectional survey of 715 randomly selected patients visiting three secondary diabetes care centres across Andhra Pradesh – Vijayawada, Tenali and Tirupati between December 2020 and January 2021. We collected participants demographic data and history of comorbidities.

Results:

During lockdown, 59.3% of the respondents were concerned about health management, 63.9% expressed fear of contracting infections while visiting hospitals. Majority (70%) did not prefer visiting hospitals treating COVID-19 patients, while 18.3% reluctantly consider only if COVID-19 ward was kept isolated. Measures such as wearing personal protective equipment sanitisation and thermal screening and social distancing in outpatient settings/waiting areas were demanded by 89.7%, 84.5% and 60% of respondents, respectively. Concurrently, there is an increasing trend (from 2.8% to 24.9%) in teleconsultation. About 31.7% show an inclination to continue teleconsultations even after COVID-19 era with 51.7% recognising telemedicine as a time-saving option. Among interested patients (54%) with no prior experience of telemedicine, 41.5% reported concerns due to lack of technical equipment and improper training. About 23.1% were skeptical of effective personalised treatment. Sample collections at home (75.3%), home monitors (63.3%), medication delivery (47.3%) and telemedicine (31.7%) are preferred choices.

Conclusion:

On a real-time basis, participants are willing to share their health status-related data with their health-care team. Succumbing to the worldwide COVID-19 experience, both health-care providers and patients need to adopt and devise a ‘new normal’, a paradigm for addressing both health-care providers’ and patients’ requirements.
A simulation study to compare physiological responses to hypoxia and exercise between anaemic subjects and healthy controls
Authors: Kumar Ashwini , Sinha Biswajit , SR Santhosh , Mishra Pratibha
Published: October 2022

Objectives:

Military flying is a complex task and requires high level of physical fitness of aviators. Various aviation stressors such as acceleratory force, hypoxia, cold weather conditions and decompression sickness place enormous stress on human physiological systems of the aviators. Individuals with Hb <13 g/dL (males) are being placed in the lower medical category which makes them unfit to fly. The present study was undertaken to assess the implication of low haemoglobin (Hb) on exercise capacity and hypoxia tolerance.

Materials and Methods:

Twenty-five individuals with anaemia and 15 healthy controls participated in the study. The participants were subjected to normobaric hypoxia (NH) equivalent to an altitude of 15,000 feet. Different physiological parameters such as heart rate (HR), systolic and diastolic blood pressure (SBP and DBP), respiratory rate (fR) and arterial oxygen saturation (SpO2) were measured during NH. Participants also performed maximal aerobic capacity (VO2 max) and maximal anaerobic capacity test in bicycle ergometer.

Results:

HR, SBP, DBP and fR in anaemic subjects were higher than healthy controls during NH, whereas SpO2 in anaemic subjects was lower as compared to healthy controls. Anaemic individuals had a lower VO2 max than their healthy counterparts. Critical power and anaerobic work capacity were lower in anaemic subjects than healthy controls.

Conclusion:

There is a deterioration in exercise capacity and hypoxia tolerance in individuals with low Hb levels. Adequate precaution should be exercised for permitting military aviators to fly with low Hb level.
Flipped pedagogical approach in teaching skeletal muscle physiology for undergraduate medical students
Authors: Prabhu Rekha , Prabhu Girish
Published: October 2022

Objectives:

Medical teachers need to use different pedagogical approaches to enhance student learning. Students are exposed to the flipped classroom (FC) in addition to the other teaching approaches which may enhance the comprehension, interpretation, and analytic skills of the students. The objective of this study was to compare the test scores obtained after the FC teaching session with the test scores obtained after a traditional classroom teaching session on a topic in skeletal muscle physiology delivered to 1st-year undergraduate medical students.

Materials and Methods:

Twenty-one 1st-year undergraduate medical students, undergoing a musculoskeletal system module at a private medical college were involved in this study. Students in the flipped pedagogical method were required to read the notes and power-point slides provided in addition to watching the prerecorded lecture videos before class. During the class, there was a topic review session followed by a small case discussion in groups. In the traditional classroom, students were advised to attend the lectures but there were no recorded videos to watch before the session. The effectiveness of the two types of pedagogical approaches was tested through pre-test and post-test using multiple-choice questions. The students’ perception of FC was collected through a semi-structured validated questionnaire.

Results:

The pre-test mean score was higher for FC (5.48 ± 1.44) when compared to the traditional classroom (3.19 ± 1.4). In our study, the scores from pre-test to post-test in a traditional classroom showed statistically significant improvement (P = 0.0014) but were not statistically significant in the FC. In the flipped pedagogical approach, the difference between mean correct responses for question number 5 (P = 0.031) in pre-test and post-test was statistically significant. There was an improvement in the mean scores in all the eight questions between pre-test and post-tests in the traditional pedagogical method of teaching. About 79.6% of students agreed that they watched all the assigned videos and 78.6% of students completed reading the assigned power-point presentation slides before coming to the FC. About 78.5% agreed to learn more topics in FC format and 78.6% of students agreed that FC was more engaging and interesting in comparison to a traditional class.

Conclusion:

Our study showed that flipped and traditional pedagogical approaches both enhance student learning.
Temporal variation in sandstone composition of Miocene Jatiluhur Formation in the Bogor Trough, West Java, Indonesia
Authors: Abdurrokhim  , Adhiperdana Billy , Hendarmawan
Published: October 2022

Bogor Trough in the West Java are typified by turbidity deposits with the source are mostly characterized by volcanoclastic materials from the southern area. The Trough actually receipt the sediment from both volcanoclastic materials from the south and continental source from the north. But, the discussions of sediments in term of composition and   temporal variation are rare to be reported, especially the sediments from the north. This manuscript intends to discuss the temporal variation in detrital compositional and depositional facies of the Neogene sediments that delivered from the north (i.e., Sundaland) into the Bogor Trough, which is represented by Miocene Jatiluhur Formation.

A total of 36 selected samples have been taken for identifying the minerals using a polarization microscope. Modal analysis of the Gazzi-Dickinson method was applied for this provenance study of sandstones samples, which are consisting largely of quartz and feldspar, then sedimentary rock and volcanic rock fragments, glaucony, mud chips and skeletal fragments.

Sundaland, a continental block highland area in the north, is interpreted to have been the provenance of sediments of the Jatiluhur Formation, which is also considered to be the source area for the Paleogene sediments. Granitic igneous rocks are interpreted as the source of dominance of monocrystalline quartz grains, or the product of long-distance transport of polycrystalline quartz from metamorphic rocks

But, however late Miocene samples (upper part of formation) represent that the size and amount of glauconite grains are increasing, and texturally mud supported. Volcanic rocks materials are also observed. The upper part of Jatiluhur Formation records the starvation of sediment discharge into the basin, which has been also promoted for development of carbonate reef Klapanunggal Formation in the self-margin setting, and suggesting that the basin have directly received or indirectly some contemporaneous volcanic provenances sediment from the southern area.
Violencia estructural y las tecnologías de la información
Authors: Rodríguez Jorge Mario
Published: October 2022

Este artículo examina la forma en que las nuevas tecnologías de la información hacen posible un tipo de violencia que se basa en el socavamiento de los pilares del comportamiento ético-racional en un sentido integral. Sostiene que dicha causalidad, de tipo estructural, emerge de la conjunción de tres factores. En primer lugar, una disrupción que no solo provoca inestabilidad social y personal, sino que no es compatible con las posibilidades de una reorganización política democrática. En segundo lugar, las tecnologías inducen una progresiva erosión de las capacidades reflexivas del ser humano —un factor que milita no solo a favor de la dispersión de noticias falsas, sino que provoca polarización, conspiraciones y otro tipo de malestares digitales. En tercer lugar, las tecnologías digitales erosionan la ética dado que eclipsan al Otro, un aspecto esencial para la constitución de la subjetividad ética y la acción responsable. De este modo, las redes sociales y las nuevas tecnologías no hacen posible las experiencias éticas fundamentales, lo cual se muestra en las dificultades que encuentra la ética de la inteligencia artificial. Estos argumentos sugieren que el paso civilizacional para evitar los peligros del totalitarismo digital radica en promover el sentido incluyente de comunidad que surge de la conciencia de la relación de nuestra interdependencia con todo el Universo. Los peligros de la tecnología son irresolubles, si se permite que la disrupción que provoca se prolongue de manera incontrolable, razón por la cual es necesario regular democráticamente sus usos, no permitiendo su desarrollo secreto.
O coração da loucura: Nise da Silveira e a importâncias da história de vida e das técnicas expressivas na resiliência à violência em saúde mental
Authors: Martinez Monica
Published: October 2022

O presente estudo debruça-se sobre o filme “O coração da loucura: Nise da Silveira” para abordar a importâncias da história de vida e das técnicas expressivas na resiliência à violência em saúde mental. Nise (1905-1999) foi uma psiquiatra brasileira reconhecida mundialmente por sua abordagem junguiana no tratamento de pacientes psicóticos. A pesquisa tem como foco a representação que a película faz da protagonista no processo de evolução do tratamento dos transtornos mentais neste período (1944-1956). O argumento é o de que o filme, embora tome decisões de reconstrução cronológica que eventualmente se afastam dos fatos, imortaliza o pioneirismo de uma mulher formada em medicina nos anos 1930, numa sociedade sexista como a brasileira de então, de uma forma suficientemente boa para que este registro seja transmitido e debatido por uma audiência mais ampla, que se interessa pela película por variados motivos.
Territórios do torcer: futebol, violência e política
Authors: Paes Lopes Felipe Tavares
Published: October 2022

Este trabalho (A expressão “territórios do torcer” faz alusão e homenageia a obra de Bernardo Borges Buarque de Hollanda, que a emprega em diversas produções, como em Hollanda e Florenzano (2019)) analisa de que maneira o espaço urbano é apropriado pelas torcidas organizadas e como essa apropriação molda a dinâmica dos conflitos entre elas. Também discute como ele é apropriado por um novo agrupamento de torcedores: os coletivos antifascistas. Para tanto, apoia-se nos resultados parciais de uma pesquisa sobre antifascismo e futebol no contexto da cidade de São Paulo, que adotou múltiplos procedimentos metodológicos. Entre outras coisas, o trabalho indica que as torcidas organizadas dividem a cidade em territórios amistosos e territórios hostis que os coletivos antifascistas costumam converter as ruas em espaços de solidariedade e apoio mútuo.
Detailed insights into lignin stabilisation and carbohydrate chemical nature in the H-transfer RCF process: On the role of solvent fractionation in the structural profiling of lignin oil
Authors: Rinken Raul , Posthuma Dean , Rinaldi Roberto
Published: October 2022

Reductive Catalytic Fractionation (RCF) of lignocellulosic materials produces lignin oil rich in monomer products and high-quality cellulosic pulps. RCF lignin oil also contains lignin oligomers/polymers and hemicellulose-derived carbohydrates. The variety of components makes lignin oil a complex matrix for analytical methods. As a result, the signals are often convoluted and overlapped, making detecting and quantifying key intermediates challenging. Therefore, to investigate the mechanisms underlining lignin stabilisation and elucidate the structural features of carbohydrates occurring in the RCF lignin oil, fractionation methods reducing the RCF lignin oil complexity are required. This report examines the solvent fractionation of RCF lignin oil as a facile method for producing lignin oil fractions for advanced characterisation. We demonstrate solvent fractionation using small volumes of environmentally benign solvents (methanol, acetone and ethyl acetate) to produce multigram lignin fractions comprising products in different molecular weight ranges. This feature allowed for determining structural heterogeneity across the entire molecular weight distribution of the RCF lignin oil via high-resolution HSQC NMR spectroscopy. This study provides detailed insight into the role of the hydrogenation catalyst (Raney Ni) in stabilising lignin fragments and defining the chemical nature of hemicellulose-derived carbohydrates in lignin oil obtained by the H transfer RCF process.
Machine learning prediction of open metal sites in metal-organic framework catalysts
Authors: Guo Huixuan , Ma Jiahao , Zhong Yueshan , Yin Yuhui , Chen Mingcan
Published: October 2022

Metal-organic frameworks (MOF) have garnered much attention as promising catalysts due to their tunable porosity, high surface area, and diversity of catalytic metal clusters and organic linkers as building blocks. The presence of open metal sites (OMS) significantly influences the catalytic, adsorption, and separation capabilities of MOFs. However, common laboratory methods are indirect and can suffer from structural heterogeneity. Computational methods, including machine learning, play a central role in the rational design of MOFs, yet in silico detection of OMS still relies heavily on computationally expensive simulations. In this work, we use extreme gradient boosting (XGboost) and random forest (RF) methods to predict the existence of OMS in various MOF compounds based on structural and chemical features. RF provided a higher prediction accuracy of 0.891 compared to 0.865 of XGBoost. Average ionization energy, average electron affinity, and fraction of electrons in d orbitals exhibited the highest importance scores across the two models. These prediction models not only provide novel insights into the structural-property relationship between MOFs and OMS, but also would enable accurate and efficient exploration of MOFs that would give rise to OMS, facilitating the engineering of sorption, separation, and catalytic properties.
VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome
Authors: Cioffi Sara , Flore Gemma , Martucciello Stefania , Bilio Marchesa , Turturo Maria Giuseppina , Illingworth Elizabeth
Published: October 2022

The loss of a single copy ofTBX1accounts for most of the clinical signs and symptoms of 22q11.2 deletion syndrome, a common genetic disorder that is characterized by multiple congenital anomalies and brain-related clinical problems, some of which likely have vascular origins.Tbx1mutant mice have brain vascular anomalies, thus making them a useful model to gain insights into the human disease. Here, we found that the main morphogenetic function of TBX1 in the mouse brain is to suppress vessel branching morphogenesis through regulation ofVegfr3. We demonstrate that inactivatingVegfr3in theTbx1expression domain on aTbx1mutant background enhances brain vessel branching and filopodia formation, whereas increasingVegfr3expression in this domain fully rescued these phenotypes. Similar results were obtained using an in vitro model of endothelial tubulogenesis. Overall, the results of this study provide genetic evidence thatVEGFR3is a regulator of early vessel branching and filopodia formation in the mouse brain and is a likely mediator of the brain vascular phenotype caused byTbx1loss of function.
Machine learning for the prediction of phenols cytotoxicity
Authors: Douali Latifa
Published: October 2022

Quantitative structure-activity relationships (QSAR) are relevant techniques that assist biologists and chemists in accelerating the drug design process and help understanding many biological and chemical mechanisms. Using classical statistical methods may affect the accuracy and the reliability of the developed QSAR models. This work aims to use a machine learning approach to establish a QSAR model for phenols cytotoxicity prediction. This issue concern many chemists and biologists. In this investigation, the dataset is diverse, and the cytotoxicity data are sparse. Multi-component description of the compounds has then been considered. A set of molecular descriptors fed the deep neural network (DNN) and served to train the DNN. The established DNN model was able to predict the cytotoxicity of the phenols at high precision. The correlation coefficient at the fitting stage was higher than other statistical methods reported in the literature or developed in the present work, specifically multiple linear regression (MLR) and shallow artificial neural networks (ANN), and was equal to 0.943. The predictive capability of the model, as estimated by the coefficient of determination on an external predictive dataset, was significantly high and was about 0.739. This finding could help implement many molecular descriptors relevant to describing the compounds, representing the effects governing the phenols' cytotoxicity toward Tetrahymena pyriformis, avoiding overfitting and outlier exclusion.
An Improved particle swarm optimization based on lévy flight and simulated annealing for high dimensional optimization problem
Authors: Bashath Samar , Ismail Amelia Ritahani , Alwan Ali A , Hussin Amir Aatieff Amir
Published: October 2022

Particle swarm optimization (PSO) is a simple metaheuristic method to implement with robust performance. PSO is regarded as one of the numerous researchers' most well-studied algorithms. However, two of its most fundamental problems remain unresolved. PSO converges onto the local optimum for high-dimensional optimization problems, and it has slow convergence speeds. This paper introduces a new variant of a particle swarm optimization algorithm utilizing Lévy flight-McCulloch, and fast simulated annealing (PSOLFS). The proposed algorithm uses two strategies to address high-dimensional problems: hybrid PSO to define the global search area and fast simulated annealing to refine the visited search region. In this paper, PSOLFS is designed based on a balance between exploration and exploitation. We evaluated the algorithm on 16 benchmark functions for 500 and 1,000 dimension experiments. On 500 dimensions, the algorithm obtains the optimal value on 14 out of 16 functions. On 1,000 dimensions, the algorithm obtains the optimal value on eight benchmark functions and is close to optimal on four others. We also compared PSOLFS with another five PSO variants regarding convergence accuracy and speed. The results demonstrated higher accuracy and faster convergence speed than other PSO variants. Moreover, the results of the Wilcoxon test show a significant difference between PSOLFS and the other PSO variants. Our experiments' findings show that the proposed method enhances the standard PSO by avoiding the local optimum and improving the convergence speed.
Incremental multiclass open-set audio recognition
Authors: Jleed Hitham , Bouchard Martin
Published: October 2022

Incremental learning aims to learn new classes if they emerge while maintaining the performance for previously known classes. It acquires useful information from incoming data to update the existing models. Open-set recognition, however, requires the ability to recognize examples from known classes and reject examples from new/unknown classes. There are two main challenges in this matter. First, new class discovery: the algorithm needs to not only recognize known classes but it must also detect unknown classes. Second, model extension: after the new classes are identified, the model needs to be updated. Focusing on this matter, we introduce incremental open-set multiclass support vector machine algorithms that can classify examples from seen/unseen classes, using incremental learning to increase the current model with new classes without entirely retraining the system. Comprehensive evaluations are carried out on both open set recognition and incremental learning. For open-set recognition, we adopt the openness test that examines the effectiveness of a varying number of known/unknown labels. For incremental learning, we adapt the model to detect a single novel class in each incremental phase and update the model with unknown classes. Experimental results show promising performance for the proposed methods, compared with some representative previous methods.
«Тайванська проблема» в контексті дестабілізації системи міжнародних відносин російсько-українською війною
Authors: Shevchuk Oleksandr
Published: October 2022

У статті розглядається «тайванська проблема» у контексті сучасного кризового стану системи міжнародних відносин пов’язаного з російською агресією проти України. На основі системного аналізу офіційних документів, виступів державних діячів КНР та США, публікацій провідних американських науковців з’ясовано, що відкрита агресія Росії проти України відкрила «ящик Пандори» щодо заморожених конфліктів успадкованих з часів холодної війни.

Одним з найбільш конфліктогенних серед яких є «тайванська проблема» зважаючи на залучення до неї таких світових гравців як США та КНР, і її географічне розташування в регіоні (АТР) який досить «насичений» територіальними проблемами. Особливу увагу приділено сучасному стану «тайванської проблеми» та впливу на її еволюцію російсько-української війни. У процесі дослідження встановлено, що російська агресія проти України виступила дестабілізуючим чинником системи міжнародних відносин як на глобальному, так і регіональному рівні. Разом з тим, відкрите збройне протистояння між США та КНР щодо розв’язання «тайванської проблеми» наразі виглядає малоймовірним, а гострі політичні заяви очільників як КНР, так і США є ілюстрацією як для громадян своїх країн, так і для союзників, що вони тримають ситуацію на контролі і готові вжити всіх необхідних засобів для досягнення своїх довгострокових національних інтересів.
Primer registro de un pato tepalcate (Oxyura jamaicensis) y de un pato cucharón norteño (Spatula clypeata) con coloración aberrante en el centro de México
Authors: Cayetano-Rosas Héctor , Bautista-Trejo Rogelio , Gómez-Garduño J. Oswaldo , Ramírez-Albores Jorge E.
Published: October 2022

Registramos la presencia de un individuo de pato tepalcate (Oxyura jamaicensis) con plumaje diluido y dos de pato cucharón norteño (Spatula clypeata), uno con canoso progresivo y el otro con leucismo parcial en el Lago Nabor Carrillo en Texcoco, Estado de México. Estas observaciones representan los primeros registros de coloración aberrante para estas especies en México. Documentar este tipo de casos puede ayudar a entender la frecuencia de las aberraciones cromáticas, así como mecanismos de especiación en los diferentes grupos de aves.
Leucismo parcial en el zanate mayor (Quiscalus mexicanus) en Guerrero, México
Authors: Salgado Flores Jorge Luis , Rodriguez Ruiz Erick Ruben
Published: October 2022

En la presente nota describimos un caso de leucismo parcial en dos individuos (madre e hija) de zanate mayor (Quiscalus mexicanus) en el neotrópico. Entre noviembre de 2019 a mayo de 2021 en Guerrero, México, observamos a una hembra de Q. mexicanus con leucismo parcial, conservando la simetría bilateral. Durante 18 meses, no detectamos cambios en el patrón de la coloración anormal de la hembra adulta  El día 11 de agosto del 2020, avistamos a la hembra adulta con pigmentación anormal alimentando a un juvenil, que igualmente presentaba anormalidad en la coloración del plumaje. Observamos que el leucismo en esta especie puede presentar variaciones, pero conserva la simetría bilateral. Asimismo, corroboramos que dicha anormalidad está presente desde el nacimiento, no varía con el tiempo y es trasmitido a la descendencia.
THE MOTIF AS AN IDEAL TYPE, OR TRICKSTER EPISODES IN EURASIAN FOLKLORE
Authors:   Peter the Great Museum of Anthropology and Ethnography (the Kunstkamera) of the Russian Academy of Sciences, Berezkin Yuri E. ,   European University at St. Petersburg
Published: October 2022

Folklore motif is an analytical tool created for the particular kind of research. Our purpose is to reveal routes of the interregional exchange of ideas in different periods of the past. The dissemination of ideas can be followed when we study material (archaeological sites) and nonmaterial (traditional narratives) objects created because of particular ideas adopted by people. Ideas are copied and disseminated unconsciously. The folklore motif is any unit of replication (most often an episode or an image) registered in two or more traditions. The tradition is a totality of narratives recorded for a particular ethnic group or across a particular territory. Motifs can be classified according to thematic groups that approximately correspond to genres of those narratives from which they are selected. The author analyses the results of computing trickster motifs with animal and anthropomorphic actors. The area configuration of the selected interaction spheres suggests that the spread of the motifs with anthropomorphic actors took place mostly from the late Antique period to the early New Time, and the spread of the animal tales – during the Middle Age and earlier. The influence of the Great Steppe on East Europe is noticeable for the Middle Age with the emergence of the borderline between Christian Europe, and the Asian-Africa interaction sphere is a characteristic trait of the early New Time. China is outside of this opposition.
VOTIVE PAINTING AS A NARRATIVE ABOUT A MIRACLE
Authors:   The State Institute for Art Studies, Fadeyeva Liudmila V.
Published: October 2022

The article deals with votive paintings of the Alpine region. These attractive works of folk art (and the religious culture of the Catholic South of Europe as well) are observed from the point of view of their functional aims as testimonies of a miracle that happened in human life. Votive paintings are interesting first of all as visualized stories, therefore it’s worthy of representing the perspective of the comparison between their narrative strategies and the narrative strategy of folklore legends. The author notes that the inclusion of a special inscription in the first person is optional for the picture. Moreover, Italian masters often use only formal inscriptions; they try to translate their customer’s stories into a drawing completely. However, the examination of some examples which show a parallel transmission of the event via words and images demonstrates remarkable differences in narrative strategies. It is significant that the visualization of a miracle as a divine intervention into the circumstances of a person’s life is mostly a result of the traditional iconography scheme followed by the painter; while the words of the person participating in the event are primarily focused on the reality and tiny details of what happened.
La distopía feminista: su surgimiento y evolución
Authors: Hernández Balbuena Erendira
Published: October 2022

El presente artículo tiene como objetivo dar una explicación certera sobre el modo en el que la distopía literaria feminista surge en la década de los setenta en Occidente. En el texto se propone que la literatura distópica feminista aparece a partir de la forma literaria utópica feminista. Es decir, no se atestigua el final de la literatura utópica feminista con el inicio de la década referida, sino la evolución de esta hacia otra forma narrativa adaptada a las condiciones históricas y sociales de la época, más escéptica y cautelosa. Así, la distopía feminista emerge como una manifestación artística crítica, coincidente con las olas del feminismo activista.

Si bien, la forma clásica de la distopía siempre denotó un rechazo por los modelos utópicos, esta sufriría una transformación nunca antes suscitada, casi en contra de sus propios fundamentos. La distopía feminista guarda en sí misma las censuras a regímenes totalitarios y el rechazo a las relaciones de género opresoras, pero permite fijar la mirada en un futuro mejor, no perfecto (como el de la utopía), más bien, realizable. Las distopías feministas se diferencian de la tradición distópica clásica porque centran sus narraciones en personajes femeninos, destacando así los horrores de sociedades tiránicas sufridos específicamente por las mujeres, así como el papel activo de estas para la liberación de su comunidad.
A New “Consumption-production” Market Model
Authors: Qiu Xiadong
Published: October 2022

Based on the long tail model, this paper assumes a new form of mutual change between producers and consumers and obtains a consumption and production economic model adapted to the modern market economy, and carries out practical verification of the model. The conclusion is that the main body of the future market economy will change from producers to consumers.
A Study on Influencing Factors of Happiness of Urban Low-income Groups
Authors: Li Zhouhe
Published: October 2022

With the completion of the strategic vision of building a moderately prosperous society in an all-round way in 2020, China’s economic development has entered a new normal. The concept of innovative, coordinated, green, open and shared development will lead China’s economic progress and development. However, the development of urban and rural areas and regions in China is still not coordinated, and the sudden COVID-19 outbreak has caused a serious impact on urban low-income groups. Due to the characteristics of poor employment stability, low income and single source, as well as greater family pressure of urban low-income groups, the author focuses on the influencing factors of their feelings of happiness. This paper assumes that the satisfaction degree of residents’ needs is positively correlated with residents’ feelings of happiness. Based on Maslow’s hierarchy of needs theory, this paper analyzes the factors that may affect the happiness of urban low-income groups in five levels, and explores the special needs and difficulties of urban low-income groups in the context of the epidemic. So as to find ways to improve the happiness of urban low-income people to provide reference.
Feasibility analysis of paddy-fish (Minapadi) system business in Toraja, South Sulawesi
Authors: Yusuf Limbongan
Published: October 2022

Paddy-fish (Minapadi) is a fish and rice maintenance system at a particular time and in the same place. Generally, Paddy-fish activities are done in rice fields. The rice field constructs are slightly different from the patterns of excavations in some parts for puddles. This study aims to analyze the feasibility of the Paddy-fish business from four aspects: NPV, Net B/C, IRR, and PBP. Research has been conducted in Makale, Toraja, and South Sulawesi Province. The research method used was a quantitative approach by using a survey. The study was used open questionnaires. The data were collected by using the purposive sampling technique. It involved 30 respondents of farmers who do Paddy-fish activities. The data analysis method used was a financial analysis covering; estimated values of NPV, Net B/C, IRR (Internal Rate of Return) and PBP (Payback Period). The study shows that the Paddy-fish business is very feasible to strive. The four indicators of business feasibility show a decent indication of effort. NPV value was 13,139,008 where the value implies >0, net value B/C was 2.52 where the value implies >1.0, IRR value was 20.47% where the value implies >MARR (18%), and payback period value was 1,917,108 in the second year of business.
Analisis Strategi Pemasaran Produk Makcan Food di Masa Pandemi Covid-19
Authors: Pangestu Adinda Rizky Hayu
Published: October 2022

During the Covid pandemic, not all MSMEs in the trade sector suffered a rise in demand. However, there are still problems that arise such as difficulty in obtaining raw materials, weather conditions and significant price increases, that can be posing a threat to the production and distribution process. So, many have swerved to replace the product with another product. The aim of this study was to analyze the marketing strategy of MSMEs products in Gresik during the pandemic, especially Makcan Food products. This type of research is a qualitative research with a literature study approach. The type of data used is primary data with data retrieval conducted through online interviews with WhatsApp voice notes and directly. The results of this study prove that not all businesses built after COVID-19 have experienced difficulties and declines. Business owners must also be able to pick up balls that can be used as opportunities to continue to innovate and be creative, as well as the right use of social media to attract consumer interest. This research can be considered in determining the right marketing strategy to increase sales of Makcan Food products. This research is limited to Makcan Food, to find out more about the impact of Covid-19 on a business. Might be able to do research in other objects and areas
Pengembangan Mobile Pocket Book Pada Mata Pelajaran Komputer Dan Jaringan Dasar Kelas X Di Smk
Authors: Mufiddah Nuurin Lailatul , Hasanah Fitria Nur
Published: October 2022

Kesulitan yang dialami peserta didik dalam memahami dan mengulang materi pembelajaran yang disampaikan, karena keterbatasan media dan waktu belajar di sekolah. Penelitian ini bertujuan untuk menghasilkan sebuah produk dan mengetahui kelayakan mobile pocket book pada mata pelajaran komputer dan jaringan dasar di SMK Yapalis Krian. Jenis penelitian yang digunakan yaitu Research and Development (R&D) dengan menggunakan model pengembangan ADDIE yang terdiri atas Analyze, Design, Develop, Implement, Evaluate. Subjek penelitian ini adalah peserta didik kelas X-TKJ yang berjumlah 10 siswa. Uji kelayakan dilakukan oleh ahli materi dan ahli media serta hasil respon para peserta didik, hasil validitas penelitian ini diperoleh presentase 90,8% dengan kategori Sangat Layak untuk media. Presentase 88,75% dengan kategori Sangat Layak untuk materi, serta presentase 86% dengan kategori Sangat Layak untuk respon para siswa. Berdasarkan hasil tersebut dapat disimpulkan bahwa mobile pocket book pada mata pelajaran komputer dan jaringan dasar sangat layak digunakan sebagai alternatif dan variasi media pembelajaran baru di SMK Yapalis Krian.
Kuşakların Mobil Cihaz Kullanım Tercihleri ve Mobil Cihazların İnternet Alışverişinde Kullanımını Etkileyen Faktörler
Authors: GÜRÜN Seda , İKİKAT TÜMER Emine
Published: October 2022

Günlük hayatımızda önemli bir yeri olan teknoloji ve internet kullanımı insanların zorunlu ya da lüks ihtiyaçlarını karşılamalarını sağlayarak dijital pazarlama kanallarının farklı yaş grupları tarafından kullanılabilir olmasına katkıda bulunmuştur. Bu çalışmada kuşakların telefon, bilgisayar ve tablet gibi mobil cihazları kullanımları ve bu cihazlar aracılığıyla internet alışverişi yapma durumlarını etkileyen faktörlerin belirlenmesi amaçlanmıştır. Amaca uygun olarak Kahramanmaraş ilinde yaşayan kuşaklarla toplam 384 anket yapılmış ve elde edilen veriler tanımlayıcı istatistikler ve Lojistik Regresyon ile analiz edilmiştir.Analiz sonucunda akıllı telefon ile internet alışverişi yapma durumu üzerinde cinsiyet ve medeni durum istatistiki olarak önemli olduğu saptanmıştır. Bilgisayar kullanarak internet alışverişi yapma durumu üzerinde Z ve Y kuşağı ve gelir düzeyi değişkenleri etkili iken tablet aracılığıyla internet alışverişi yapma durumu üzerinde cinsiyet ve eğitim değişkenleri önemli bulunmuştur.Teknolojinin günlük hayata yönelik olumlu etkisinden faydalanılması ve kuşaklar arasında teknolojik yeniliklere uyum konusunda büyük farklılıkların oluşmaması açısından dijital okuryazarlık projelerine tüm kuşakların dahil edilmesi gereklidir.