bluuebunny/crossref_metadata_2025 huggingface dataset:
Customers’ Satisfaction On Digital Banking System With Reference To Select Public Sector Banks In Karnataka
Authors: Dr. R. Kasilingam  , Ms. Thanuja. V
Published: January 2024

Digital banking is one of the most significant innovations in the banking industry that has been around for a long time. While there are many benefits that consumers get from using online banking, there are also some major challenges and challenges that marketers in the online banking industry face. The main challenges that internet banking marketers need to overcome in order to succeed in this industry are low marketing budgets, traditional bank behavior, security, technological issues, and transaction issues. As the years have passed by, digital banking has become more and more popular in the banking industry. Nowadays, the concept of digital banking is accepted in the world and it has gained popularity as a way of doing business. The unstoppable power of digital technology is transforming the financial services industry. This study seeks to identify the differences in problems faced by clients of different public sector banks when using digital banking services. 600 participants were randomly selected from those who had access to digital banking in Karnataka, and the primary data collected through a questionnaire was used as the basis for the analysis. The data was then interpreted using Statistical Processes Statistics (SPSS) and chi-square analysis, as well as a t-test.
Comparison of the analgesic effect of oral morphine with that of intravenous morphine in pediatric patients: multicenter open-label randomized blinded prospective clinical study
Authors: Belousova Ekaterina I. , Matinyan Nune V. , Tsintsadze Anastasia A. , Kovaleva Ekaterina A. , Valiev Timur T. , Gildeeva Geliya N. , Baklykova Oksana V.
Published: January 2024

BACKGROUND: Certain children with recurrent episodes of acute nociceptive pain experience chronic pain. In accordance with the recommendations of the World Health Organization, short-acting morphine is the main drug used to relieve severe pain and breakthrough pain. In published studies, morphine provided adequate analgesia in the majority (90%) of the patients; however, no such studies have compared the use of morphine tablets with a control group of pediatric patients.
OBJECTIVE: To evaluate the effectiveness and safety of morphine tablets at a dose of 5 mg and compare them with those of morphine given intravenously at a dose of 10 mg/mL in children with severe pain syndrome in the postoperative period.
MATERIALS AND METHODS: A multicenter open randomized blind prospective clinical study was conducted in parallel groups of 100 patients aged 3–18 years with severe pain syndrome in the postoperative period between September 21, 2020, and December 15, 2022. Cumulative morphine consumption, visual analog scale analgesic efficacy, patient satisfaction scores, and adverse events (AEs) / serious adverse events (SAEs) were assessed.
RESULTS: The comparative analysis of the average values of the total number of doses of an additional analgesic drug administered during treatment with the study drug (group 1)/comparison drug (group 2) in patients of different age groups (cohorts 1, 2, 3) did not reveal significant differences (p=0.05). This finding indicated the equal effectiveness of the used forms of drugs in both groups. Moreover, no significant differences were noted in the development of AEs associated with the study drug (group 1) compared with AEs of the reference drug (group 2) in patients of different age groups (cohorts 1, 2, 3); (p=0.05).
CONCLUSION: The study demonstrated the effectiveness and safety of the study drug in tablets in comparison with an injection drug in children with severe pain syndrome.
Cryoanalgesia of the ankle joint: clinical cases in the practice of a doctor of interventional pain treatment
Authors: Ushakov Aleksey A. , Antipin Eduard E. , Andriychuk Ivan V. , Konovalova Svetlana G.
Published: January 2024

BACKGROUND: Currently, with the advent of the cryoablation device, much attention is paid to cryoanalgesia of large joints, however, the pathology of smaller structures can also bring discomfort and reduce the patient’s quality of life. The article presents 3 cases of successful treatment of ankle arthrosis at the Multi-Specialty Center for Pain Treatment and Rehabilitation «Anesta» (Arkhangelsk), presenting the author’s method of joint denervation and its detailed description.
CLINICAL CASES DESCRIPTION: Three patients were presented. The first with arthrosis of the knee and ankle joint, the second patient — after an accident with purulent-septic complications and violation of the anatomical integrity of the ankle joint, the third — with extensive concomitant pathology and severe arthrosis. All patients were satisfied with the procedure and its impact on the quality of life in the postoperative period. An anatomical rationale and a detailed description of the relevance of the ankle joint cryoanalgesia method are provided. Cryoanalgesia of the ankle joint was tested on cadaver by introducing liquid silicone into the places where the cryoprobe was installed, which confirmed the interest of the sensory branches going to the joint capsule. Due to the fact that the method is proprietary, and the use of cryoanalgesia is limited on the territory of the Russian Federation, there is very little literature data regarding the procedure for performing cryoanalgesia of the ankle joint, however, as experience is gained, we assume that this procedure will become a good alternative to surgery for arthrosis ankle joint.
CONCLUSION: The presence of pain has an extremely negative impact on the general condition of patients. The presented author’s technique can significantly improve the quality of life of many patients, minimizing pain in both large and small joints.
Cloud Computing for Efficient Data Storage and Processing in Maritime Logistics
Authors: Röseler Cornelius , Backhuß Jan-Lukas , Aksentijević Saša , Tijan Edvard
Published: January 2024

Considering that the maritime logistics is by volume and financial value the largest logistics sector
enabling global trade, the number of supply chains is constantly growing, as well as the number of
supply chain stakeholders. Due to the large number of stakeholders in the supply chains, the volume
of generated data is enormous. Therefore, it is necessary to implement modern and intelligent
solutions for processing and storing the data. One possible solution for processing and storing the
data in maritime logistics is cloud computing. There are different approaches to implementing cloud
computing in maritime logistics. In this paper, the authors present a detailed structure of the maritime
cloud and compare it with the legacy systems. Finally, the advantages and challenges arising from the
implementation of cloud computing in maritime logistics are analyzed.
Global sensitivity analysis of the dynamics of a distributed hydrological model at the catchment scale
Authors: Radišić Katarina , Rouzies Emilie , Lauvernet Claire , Vidard Arthur
Published: January 2024

The PESHMELBA model simulates water and pesticide transfers at the catchment scale. Its objective is to help the process of decision making in the common management of long-term water quality. Performing the global sensitivity analysis (GSA) of this type of model is necessary to trace the output variability to the input parameters. The goal of the present work is to perform a GSA, while considering the spatio-temporal nature and the high dimensionality of the model. The output considered is the surface moisture simulated over a two-month period on a catchment of assorted mesh elements (plots). The GSA is performed on the dynamical outputs, rewritten through their functional principal components. Sobol’ indices are then estimated through polynomial chaos expansion on each principal component. The analysis differs between the two types of behaviour observed in the surface moisture outputs. The hydrodynamic properties of the surface soil have a dominant influence on the average surface moisture. Nonetheless, the parameters describing deeper soil layers influence the output dynamics of those plots where the surface moisture is saturated. We obtain Sobol’ indices with high precision while using a limited number of model estimations and considering the models spatio-temporal nature. The physical interpretation of the GSA confirms and augments our knowledge on the model.
Patent protection in the laws of Iran and the emphasis of European Union on the trips agreement
Authors: Sasani Rababe Rostam
Published: January 2024

O direito de patente, a exploração do pensamento e da iniciativa do inventor representam um direito financeiro que pode ser negociado. Contudo, como este direito é imaterial e intangível, a propriedade não pode ser reivindicada apenas pela posse física. Em vez disso, o legítimo proprietário deve ser o primeiro indivíduo que o alcançou através de muito trabalho e esforço, permitindo-lhe beneficiar exclusivamente dele e evitando que os imitadores utilizem os esforços do inventor livremente e sem esforço. O registro de uma patente em nome do inventor torna-se crucial, pois serve como prova de que o titular é a pessoa original que concebeu a invenção com sucesso, estabelecendo sua propriedade legítima. Portanto, as patentes e outros activos intangíveis desempenham um papel vital no estabelecimento da propriedade dos inventores. O objetivo deste artigo é familiarizar os inventores com os procedimentos de patentes e enfatizar a importância do registro de suas patentes para garantir a proteção. Também analisa e estuda os sistemas de proteção de patentes nas leis do Irão e da União Europeia. A pesquisa conclui que para aceitar o acordo TRIPS e ingressar na Organização Mundial do Comércio são necessários esforços consideráveis, que incluem o alinhamento das leis nacionais relativas às invenções com regulamentações internacionais, como as da Organização Mundial do Comércio. Precisa-se cobrir as lacunas existentes nas nossas leis para promover a nossa adesão à Organização Mundial do Comércio (OMC) e para liberalizar o comércio, eliminando barreiras comerciais, garantindo que não haja desculpas para não aderir à organização.
Civic activism of russian youth: behavioral practices and attitudes in the digital space
Authors: Eflova Maria , Maximova Olga , Minzaripov Riyaz , Nagmatullina Lyudmila
Published: January 2024

O artigo apresenta os resultados da pesquisa realizada na forma de uma pesquisa online em massa com jovens russos em 2022. São descritas a dinâmica do ativismo cívico digital da geração jovem, suas práticas comportamentais e atitudes. Um aspecto separado do artigo é dedicado a formas específicas de ativismo cívico digital. Apresenta a distribuição das opiniões dos jovens entrevistados sobre a sua consciência nesta direção e o grau do seu envolvimento nas diversas formas de ativismo digital. Os autores concluem que a participação dos jovens em atividades socialmente significativas influencia o processo de formação de um conjunto internamente ordenado de qualidades cívicas, fortalece o significado de qualquer ação realizada e, no contexto dos novos desafios e oportunidades do ambiente digital, contribui para a ativação da posição cívica dos jovens.
Fraud as a type of theft: issues of legal regulation
Authors: Aliev Vagif , Valeev Artem , Zhirov Ruslan , Nikolaeva Yulia , Oliempiev Anatoly
Published: January 2024

A fraude como forma de desfalque é um tipo de crime bastante comum e difícil de resolver (de acordo com as estatísticas dos últimos anos). O objetivo do artigo é estudar o conceito, o conteúdo e a natureza da fraude como forma de furto no direito penal russo. A técnica de aquisição fraudulenta do direito à propriedade alheia é idêntica, mas estamos falando de uma variante exclusiva de furto como a aquisição de direitos de propriedade. O principal método estabelecido na base da solução do problema consiste no estudo estatístico jurídico comparativo das possibilidades de revelação desse tipo de crime como fraude. No artigo, os autores investigaram alguns artigos do atual Código Penal da Federação Russa, tentaram analisar e chegar a uma conclusão sobre a novidade e a necessidade de adotar novos artigos. Conclui-se que a fraude pode ser expressa de forma ativa, expressa no relato deliberado de informações falsas ou distorcidas, ou de forma passiva, expressa na ocultação da verdade, no silêncio sobre fatos legalmente significativos. Para uma pessoa de fora que observa o processo de fraude, parece que a própria vítima transfere sua propriedade para o criminoso. Entretanto, esse não é o caso. Na verdade, a vítima o faz iludida, sem perceber que se tornou vítima de fraude (abuso de confiança).
Unity of Case-Law as an Indicator for the Development of Single Medical Space
Authors: Teremetskyi Vladyslav , Batryn Olesia , Zhuravlov Dmitro , Predmestnikov Oleg , Knysh Serhii , Knysh Zoryana , Shirshikova Ruslana
Published: January 2024

O artigo concentra-se na análise da unidade das abordagens de aplicação da lei para a resolução de disputas médicas e sua importância para a formação de um espaço médico único. Foi estabelecida uma grande influência da jurisprudência no funcionamento do sistema de saúde. Os autores analisaram as disputas mais comuns na área médica, onde o alcance de um equilíbrio razoável entre interesses privados e públicos é de grande importância para a formação de um espaço médico único, nomeadamente para: garantir a segurança da informação no setor da saúde; organização de exames médicos e vacinações preventivas; garantia de determinados direitos dos pacientes (respeito aos direitos das pessoas com transtornos mentais ou comportamentais; realização dos direitos reprodutivos; garantia do direito dos pacientes ou familiares à indenização por danos morais causados durante a prestação de cuidados médicos). Foram estudadas as principais posições jurídicas do Supremo Tribunal sobre tais categorias de casos. Observou-se que a actividade do Tribunal Europeu dos Direitos Humanos, que actua como um meio supranacional de protecção dos direitos humanos, é importante para a prática judicial nacional. Ao mesmo tempo, os autores indicaram um número significativo de desvios de práticas precedentes, que são percebidas negativamente pela CEDH e reconhecidas como violações da Convenção sobre a Proteção dos Direitos Humanos e das Liberdades Fundamentais. Estudou-se o monitoramento judicial como ferramenta moderna para garantir a qualidade dos atos normativos e meio eficaz para eliminar os vícios da legislação médica. Os autores propuseram utilizar as decisões judiciais como fontes jurídicas, a fim de superar lacunas legislativas e interpretações jurídicas ambíguas e contraditórias.
Evaluación mecánica de una mezcla asfáltica tibia (WMA) utilizando aditivos modificadores de viscosidad
Authors: Slebi Acevedo Carlos José , Zuluaga Astudillo Daniel Alberto , Gutiérrez Melgarejo Rafael
Published: January 2024

La tecnología de mezcla asfáltica tibia (WMA) ha sido un incentivo en la industria asfáltica ya que contribuye a minimizar las emisiones de gases de efecto invernadero al medio ambiente, ayudando a reducir el calentamiento global y la huella de carbono. En esta investigación se evaluó experimentalmente el impacto de dos aditivos WMA sobre las características del ligante asfáltico y la mezcla asfáltica. Entre los resultados, se destacó el impacto de los aditivos en la propiedad de viscosidad del ligante asfáltico. Ambos aditivos redujeron la viscosidad a medida que aumentaba la temperatura en la mezcla. Con respecto a las mezclas asfálticas, la adición de aditivos wma tendió a aumentar la densidad aparente, los vacíos llenos de asfalto, la estabilidad Marshall y a reducir el contenido de vacíos de aire. La incorporación de estos aditivos puede reducir entre un 0.2 y un 0.4% el contenido óptimo de betún.
Halal Food Certification and Sustainability Performance: A Conceptual Paper
Authors: Handayati Puji , Rochayatun Sulis , . Meldona
Published: January 2024

This paper hypothesizes that Halal Food Certification increases and enhances sustainability performance through a conceptual framework highlighting their connectivity. Many studies focus on Halal Food Certification with the business performance from various perspectives, but more research is required that explicitly studies certification and sustainability. Regarding the methodology, secondary sources related to topics and keywords have been implemented. This research refers to the guidelines for implementing halal certification based on quality management as a basis to be discussed in the Halal Industry. According to a literature review, Halal Food Certification could increase sustainability in three aspects: economic, social, and environmental. This study’s theoretical foundations can facilitate further in-depth investigation into both elements. Given their conceptual nature, the framework should undergo empirical testing.
Keywords: Halal Food Certification, sustainability performance, conceptual framework
Optimization of Village Tourism Development Strategy in Tulungagung: SWOT Approach
Authors: Hasyim Ibnu Abbas Muhammad , Sumarsono Hadi , Rahmawati Farida , Nuraini Dwiputri Inayati , Kustiandi Januar
Published: January 2024

Tulungagung Regency is an area in which each village has tourism potential. Mbalong Kawuk, for example, was created as a tourist attraction and family leisure by Village- Owned Enterprises (BUMDes) Sumbermulyo, in collaboration with the administration of Sumberejo Kulon Village. Due to the high level of competition for tourist attractions and family recreation in Tulungagung, the management and village government must be able to devise strategies and innovations in the development of tourist attractions in order to compete for new market spaces where other attractions do not exist. The purpose of this research is to uncover internal and external elements in Mbalong Kawuk and to build tourist development plans in the face of commercial rivalry. The SWOT data analysis approach was applied in the case study. According to the findings of this study, Mbalong Kawuk is in quadrant I, indicating that the market has both strength and potential.
Keywords: tourism development strategy, BUMDes, SWOT analysis
Intangible Assets and R&D to the Value of New IPO Companies with Financial Performance as Moderating Variable
Authors: Hanafi Falah Achmad Raihan , Ayu Rahmawati Setya
Published: January 2024

This study uses an explanatory quantitative design to determine the influence of research and development intensity and intangible assets on firm value with financial performance as a moderation variable. This study aims to add to the investor literature by providing a way to assess new companies in 2020 that initially conducted public offerings. Financial performance is used as a moderator to see whether it will strengthen the relationship between variables or weaken it. Companies in 2020 that have just made an initial public offering and disclosed research and development costs, recorded profits in financial statements, and value from intangible assets will be the sample in this study. Secondary data was used in this study from the Indonesia Stock Exchange with a moderation regression data analysis technique. This study indicates that firm value does not affect the intensity of research and development and intangible assets. However, intangible assets have a stronger relationship with firm value with moderating financial performance.
Keywords: intangible assets, R&D, firm value, financial performance, initial public offering
Argentina Evangélica. Estudios socioantropológicos sobre misiones e iglesias de César Ceriani y Mariana Espinosa (coords.)
Authors: Paz González Erick Adrián
Published: January 2024

El libro Argentina Evangélica. Estudios socioantropológicos sobre misiones e iglesias se publica en torno a los 500 años de la Reforma Protestante en 2017, con la finalidad de volver a mirar el fenómeno protestante y evangélico en América Latina, además proponer una manera de conjuntar a textos y autores que se han vuelto clave en el estudio de lo religioso.
La construcción del paisaje queer en torno al Mediterráneo
Authors: BAROS TOWNSEND MAURICIO
Published: January 2024

Esta investigación tiene por objetivo abordar dos conceptos, cuales son la liminalidad y lo queer a partir del análisis de los viajes y estadías en torno del Mediterráneo realizados por prominentes artistas durante los siglos XIX y XX. El supuesto hipotético plantea que el Mediterráneo ha ofrecido las condiciones liminales que le ha permitido convertirse en el destino preferido de viajeros con una orientación sexual queer. Estos personajes han plasmado sus intereses sexuales tanto en su obra literaria, pictórica, fotográfica, cinematográfica, etc., creando de esta manera una geografía íntima y personal que terminó por plasmarse en una arquitectura, que sirvió como refugio y teatro para su doble existencia homosexual. En ellas es posible apreciar toda una estética que podemos denominar como queer, que parte en la arquitectura y termina en la vestimenta, y que ha sido posible construir gracias a la existencia de este Mediterráneo liminal.

PALABRAS CLAVE: Queer, liminalismo, Mediterráneo, Orientalismo, arquitectura.
Gamification
Authors: De Campos Ariana , Franzão Rodrigues da Silva Amanda
Published: January 2024

Com o rápido avanço e disseminação das Tecnologias Digitais da Informação e da Comunicação, a oferta de produtos e serviços foi modificada e a necessidade de inovação foi instalada nas organizações. Nas bibliotecas, primordialmente, nas universitárias, a busca pela inovação tem sido indispensável e pauta de discussão entre bibliotecários preocupados em acompanhar o cenário de transição, aperfeiçoar os atendimentos e cultivar seus usuários, marcados por novas expectativas e comportamentos ocasionados pelo progresso e convivência com as tecnologias. O Serviço de Referência é um dos serviços oferecidos pelas bibliotecas universitárias e lida diariamente com os acadêmicos e suas respectivas necessidades e comportamentos informacionais, oferece auxilio para a pesquisa científica e nos processos de aquisição de informação relevante, sendo essencial no tripé ensino-pesquisa-extensão das instituições de ensino. O objetivo do trabalho foi apontar as possibilidades do uso do Gamification nos Serviços de Referência de Bibliotecas Universitárias. Como ferramenta inovadora, o Gamification significa utilizar da mecânica, da estética e do pensamento baseados em games para engajar pessoas, motivar a ação, promover a aprendizagem e resolver problemas. O estudo possui caráter de pesquisa exploratória quanto aos objetivos e é bibliográfico quanto aos procedimentos adotados. Como resultado, foram apontadas bibliotecas que já utilizam o mecanismo e os benefícios que podem ser adquiridos a partir do uso do Gamification para atividades realizadas nos Serviços de Referência.
Język bohaterów w utworach Michaiła Zoszczenki
Authors: Wierzbiński Jarosław
Published: January 2024

Twórczość Michaiła Zoszczenki przenosi nas w lata socrealistycznej ortodoksji, kiedy względy ideologiczne odgrywały pierwszoplanową rolę w rozmaitych sferach życia. W języku jego bohaterów manifestują się takie zjawiska, jak upolitycznienie słownictwa, manipulacje semantyczne, przewrotna argumentacja, spiętrzenie absurdów, a także fikcyjna konwersacja graniczącą nierzadko z pustosłowiem.
Wśród przykładów spekulowania słownictwem znajduje się termin идеология, który nie powinien mieć zastosowania w rozmaitych konsytuacjach. Adresatom tego słowa imputuje się cechy o wydźwięku politycznym. Intencją jego użytkowników jest wykreowanie przeciwnika politycznego. Zdumiewa też łatwość, z jaką bohaterowie Zoszczenki poddają się manipulacjom językowym, nie popadając przy tym w najmniejsze zakłopotanie. Wręcz przeciwnie, akceptują swoje nielogiczne wywody, aprobują też niezrozumiałe wypowiedzi przedstawicieli władzy.
Zasygnalizowane w artykule zjawiska są symptomatyczne i znamienne dla języka, odzwierciedlającego czasy Zoszczenki. Zoszczenko ujawnił w ten sposób mechanizmy rządzące ludzką mentalnością w porewolucyjnej rzeczywistości. Jego utwory, jakkolwiek utrzymane w tona­cji groteskowej, są swoistą formą protestu wobec politycznej manipulacji w języku. Fenomenu Zoszczenki nie sposób rozpatrywać z pominięciem przedstawionego fragmentu rzeczywistości językowej czy też w oderwaniu od czasów, w których przyszło mu tworzyć.
Machine Learning Bolsters Evidence That D1, Nef, and Tat Influence HIV Reservoir Dynamics
Authors: Cannon LaMont , Fehrman Sophia , Pinzone Marilia , Weissman Sam , O'Doherty Una
Published: January 2024

Background: The primary hurdle to curing HIV is due to the establishment of a reservoir early in infection. In an effort to find new treatment strategies, we and others have focused on understanding the selection pressures exerted on the reservoir by studying how proviral sequences change over time.
Methods: To gain insights into the dynamics of the HIV reservoir we analyzed longitudinal near full-length sequences from 7 people living with HIV between 1 and 20 years following the initiation of antiretroviral treatment. We used this data to employ Bayesian mixed effects models to characterize the decay of the reservoir using single-phase and multiphasic decay models based on near full-length sequencing. In addition, we developed a machine-learning approach utilizing logistic regression to identify elements within the HIV genome most associated with proviral decay and persistence. By systematically analyzing proviruses that are deleted for a specific element, we gain insights into their role in reservoir contraction and expansion.
Results: Our analyses indicate that biphasic decay models of intact reservoir dynamics were better than single-phase models with a stronger statistical fit. Based on the biphasic decay pattern of the intact reservoir, we estimated the half-lives of the first and second phases of decay to be 18.2 (17.3 to 19.2, 95%CI) and 433 (227 to 6400, 95%CI) months, respectively. 
In contrast, the dynamics of defective proviruses differed favoring neither model definitively, with an estimated half-life of 87.3 (78.1 to 98.8, 95% CI) months during the first phase of the biphasic model. Machine-learning analysis of HIV genomes at the nucleotide level revealed that the presence of the splice donor site D1 was the principal genomic element associated with contraction. This role of D1 was then validated in an in vitro system. Using the same approach, we additionally found supporting evidence that HIV nef may confer a protective advantage for latently infected T cells while tat was associated with clonal expansion. 
Conclusions: The nature of intact reservoir decay suggests that the long-lived HIV reservoir contains at least 2 distinct compartments. The first compartment decays faster than the second compartment. Our machine-learning analysis of HIV proviral sequences reveals specific genomic elements are associated with contraction while others are associated with persistence and expansion. Together, these opposing forces shape the reservoir over time.
Southeast Asia and the USA: Parameters of Interaction
Authors: Rogozhina N. , Rogozhin A.
Published: January 2024

The article analyzes the factors influencing the nature of cooperation between Southeast Asian countries with the United States and the directions of its implementation in the context of the escalating rivalry between the United States and China, who seek to influence them. The US interest in the region is primarily determined by the tasks of containing China and strengthening its position in the Indo-Pacific region by expanding ties with partners and allies. The approach of the Southeast Asian countries towards cooperation with the United States is motivated by two considerations – strategic and economic. In the context of growing concerns about China’s expansion in the region and the persisting territorial disputes with it in the South China Sea, the United States in the eyes of these states is considered a stabilizing factor of the regional security system. The article points out that despite the fact that the Southeast Asian countries are interested in the presence of the United States in the region, the anti-Chinese orientation of American policy limits the potential of their strategic interaction. Case studies of individual Southeast Asian countries confirm their commitment to the principle of inclusiveness in foreign policy, which excludes choosing one party over the other. Despite the fears inherent in Southeast Asian countries about the expansion of China’s influence, they prefer to pursue a hedging policy, which in reality manifests itself in the desire to balance between competing parties in order to neutralize risks and preserve strategic autonomy. This explains the dualism of the Southeast Asian countries’ policies and affects their cooperation with the United States in the field of security, which, despite the intensification of diplomatic activities of Biden’s administration and the conclusion of a comprehensive strategic partnership agreement, is developing slowly, except for the ongoing joint military exercises and arms purchases. In general, the Southeast Asian countries are – and contribute to – solving problems they consider important, primarily in the field of economy. Contrary to the prevailing idea of China’s economic dominance in the region, the economic relations of the Southeast Asian countries with the United States have been stable for a decade, developing in an upward direction, and beneficial for the Southeast Asian countries themselves. Economic cooperation remains a priority of their interaction with the United States, despite the importance of developing security relations. Pragmatism and the acknowledgement of the emerging geopolitical situation in the region determines the parameters of interaction between the Southeast Asian countries and the United States.
European Union Development Trends: Some Aspects of Economic Integration
Authors: Chetverikova A.
Published: January 2024

The article is devoted to the analysis of the European Union development as an integration association. The economic aspects of integration within the EU as a whole as well as developing sub-integration processes are highlighted. Existing estimates show fluctuation in the level of the EU integration and its significant reduction in certain areas during some periods. The internationalization of the world economy and the increasing involvement of the EU in these processes couldn’t but have an impact on the intra-European situation. The assessment of the economic integration is made on the basis of the dynamics of the trade-investment cooperation and migration processes also. The analysis showed that different economic ties are not equally involved in the integration within the EU. If at the beginning of the XXI century the merchandise trade and FDI were comparable in terms of the level of involvement in the intra-European flows, then at present investment ties are considerably inferior to trade ones, having refocused on countries outside the EU. There is a steady trend in increasing of the share of citizens of non-EU countries living in the EU as well as EU citizens born in non-EU countries. The complexity of the European integration is traced by the example of sub-integration processes in the Visegrad Group. It is shown that accession to the EU has stimulated trade-investment cooperation within the “fourth”, but strong contrasts between members continue to persist. One of the main factors of the participation level in sub-integration is the economy size. Due to national features investment ties in terms of outstock are involved in subintegration processes more than trade ones. Sub-integration will continue to develop in the EU due to long-term factors, “complicating” pan-European integration processes, the non-linearity of which will remain.
Revisiting the UN reform: between the desirable and the achievable
Authors: Türk D.
Published: January 2024

The article explores whether the United Nations reform should give priority to its structures and modus operandi at the decisionmaking level, to ensure its role as a serious deliberative institution capable of guiding its vastly expanded operational arm with the necessary wisdom and vision. It is argued that the main test for the UN in the area of international peace and security should not be in its effectiveness in mobilising resources for humanitarian assistance, peacekeeping etc., but rather the quality of decisionmaking capable of preventing political tensions from deterioration into humanitarian disasters and from their descent into armed conflicts. The analysis shows the contrast between two models of the UN reform. One was an ambitious plan for an overall systemic design based on the idea of rebalancing of the principal organs of the UN through “the three councils approach”, under review of the High Level Panel on Threats, Challenges and Change back in the mid-2000s. While the main parts of the plan were not accepted and it only led to a “half way reform”, it is argued that its lessons are useful to keep in mind in approaching the question of the UN reform today. A simpler suggested model concerns the currently discussed composition of the UN Security Council. A moderate and more pragmatic approach is proposed, based on keeping the veto power intact, expanding the category of non-permanent members only, and slightly amending the UN Charter to allow immediate re-election of a non-permanent member, i. e. a possibility of a “de facto permanence”. While the author concludes that the current demand-driven and gradual approach to the UN reform that lacks overall design is likely to continue in the future, he sees the second model as a realistic possibility.
A sociabilidade e o interesse empírico pelo belo em Kant
Authors: De Farias Mesquita Jéssica
Published: January 2024

O presente artigo tem o intuito de apresentar a concepção kantiana acerca do belo empírico e sua contribuição para o modo de civilizar humano. O primeiro ponto do artigo trata de contextualizar o interesse pelo belo empírico apontando a concepção de juízo estético e do belo em Kant a fim de contextualizar a abordagem kantiana sobre os elementos estéticos da obra Crítica da Faculdade de Julgar (1790). O segundo ponto introduz as características próprias concernentes ao processo de sociabilidade humana, trazendo noções como a de sensus communis e comunicabilidade. O terceiro ponto trata de apresentar uma interconexão do processo de sociabilidade em Kant, exposto pela Terceira crítica, com outros textos kantianos que versam sobre história e antropologia. Com base nessa relação comparativa, o artigo mostra em que medida ocorre o melhoramento da sociabilidade humana a partir do interesse pelo belo empírico e como esse interesse contribui para a formação da uma sociedade civilizada.
Laboratory Methods for Ill Liver Diagnosis
Authors: Chesca Antonella
Published: January 2024

The study aimed to manage and to analyse the results of the laboratory methods, using liver samples, preparing and analizing in pathology service. This mentioned, are known as routinally practice for hepatitis C diagnosis, which conduct to hepatic cirrhosis. In this study direction, chronic liver diseases stimulate a degree of hepatocyte injury. So previously mentioned modifications, alters thet affect the liver architecture and finally ends in cirrhosis are well analyse on microscopic preparates.
Decisions That Drive Success: Navigating Effective Decision-Making in Business Management
Authors: Rezaei Rasa , Sezar Volkan
Published: January 2024

This exploration delves into the intricacies of decision-making in business management. It covers decision-making models, influencing factors, real-world case studies, and strategies for effectiveness. Emphasizing the role of data-driven approaches, the exploration highlights the transformative impact of effective decisions on organizational success. Challenges and pitfalls are addressed, providing insights for overcoming obstacles. The importance of mastering decision-making is underlined as a strategic advantage in the competitive landscape of business management. In summary, this exploration offers a nuanced understanding, empowering leaders to make informed choices that shape organizational destinies.
Sorafenib Analogue and Its Rearranged Compound: Design, Synthesis, Their In Vitro Anticancer Activity and Crystal Structure of the Rearranged Compound Dichloromethane Solvate
Authors: Yu Qunying
Published: January 2024

Cancer is a devastating disease with female breast cancer becoming the leading cause of global cancer morbidity. Herein we report the design and synthesis of a sorafenib analog 1A and its base-promoted arranged compound 1A2. Their in vitro cytotoxicity and potencies in EFGR inhibition study revealed that compound 1A displayed good antiproliferative activity in MDA-MB-231 (breast) cells with an IC50 value of 16.18±1.42 μM. Crystallization 1A2 affored 1A2a as a solvate with dichloromethane which was explicitly confirmed by the single crystal X-ray diffraction analysis.
Study of the Effectiveness of Rehabilitation using the HUBER Training 360® to Reduce the Risk of Falls in People with a Pathological Situation in Need of Functional Rehabilitation: A Randomized Control Trial
Authors: Charlotte Laurent , Charlotte Beaudart , Slomian Justine , Kaux Jean-François
Published: January 2024

1) Background: Patients with neurological disorders are particularly at risk of falling and requiret functional rehabilitation. HUBER® is a motorised rotating platform that allows simultaneous work on balance, stability and strength with continuous adaptation and immediate feedback. This study aimed to measure the impact of rehabilitation with the HUBER® on the physical performance and quality of life of patients with neurological diseases requiring functional rehabilitation. 2) Methods: 32 subjects were enrolled in CHU Liège CNRF and randomly divided into 2 groups. The first group received classical rehabilitation combined with two training sessions per week on the HUBER® for 8 weeks. The second group received their usual treatment. This randomized control trial has been registered on clinicaltrials.gov under the number NCT04687293. Physical performance and quality of life were evaluated at different time. 3) Results: There was no significant difference between the 2 groups after enrolment. In terms of physical performance, an improvement in SPPB chair stand test (p=0.021) and total SPPB (p=0.003) was observed in the HUBER® group. In terms of quality of life, a higher improvement was observed overall in the HUBER® group (p<0.05 between groups). 4) Conclusion: The HUBER® showed promising results in functional rehabilitation of patients with neurological pathologies, as a complement to classical rehabilitation management by physiotherapy.
The Research on Students' Physical Health Integrated with Extracurricular Fitness Running "Lerun" in China College Physical Education Curriculum
Authors: Zhao Xin min
Published: January 2024

Purpose：Herein, aimed to explore routines to improve students' physical health.Methods:We explored the integration of extracurricular fitness running "Lerun" into college physical education curriculum. Firstly, experimental and the referring groups were selected by experimental method, in which only the experimental group was intervened in combination with extracurricular fitness running "Lerun". After two experiments, the experimental and referring groups were compared in terms of physical fitness (speed, strength, endurance, flexibility, explosive force, etc.), sports skills, body shape, cardiopulmonary function, etc. Results:After T-test, significant differences (p<0.05) between these two groups prove that the students' physical health status of experimental group is better than that of the referring group. Conclusion：It manifests that integrating extracurricular fitness running "Lerun" into college physical education curriculum is an effective means to improve students' physical health.
Xanthogranulomatous Orchitis Combined with Contralateral Acute Pyogenic Orchitis: A Rare Case Report
Authors: Dai Yu , Meng Yan-hu , Li Ying-yi , Liu Shuang-ning
Published: January 2024

Xanthogranulomatous orchitis is a chronic, non-neoplastic inflammation that is quite rare. In this paper, we discuss the case of a 79-year-old male patient who presented with bilateral scrotum swelling and dysuria that persisted for two weeks. Despite two weeks of anti-infection treatment, the patient's symptoms persisted, leading to a decision to perform transurethral prostate resection and bilateral orchiectomy after careful consideration. After the surgery, the postoperative pathology indicated that the patient had xanthogranulomatous orchitis on the left side and acute positive orchitis with hemorrhage on the right side. Fortunately, three months after the procedure, the patient experienced no negative events and was pleased with the postoperative results.
Series y largometrajes en la encrucijada de las plataformas de streaming
Authors: Marcos Ramos María , Calvo de Castro Pablo , Martín García Teresa
Published: January 2024

El documental, como formato audiovisual, vive en la actualidad una etapa dorada. Este fenómeno se puede explicar desde muy diversos puntos de vista. Por un lado, tras una evolución durante el siglo pasado no exenta de dificultades, pero certera, en paralelo a la ficción, la implementación de medios digitales en los sistemas de producción audiovisual desde hace dos décadas supuso que directores y directoras tuvieran mayor capacidad para abordar proyectos independientes o personales con unos costes de producción infinitamente menores que los del vídeo analógico o los de la producción con celuloide.
Long-term patterns and mechanisms of plant invasions in forests: the role of forest age and land-use history
Authors: Jones Chad C. , Yamamoto Matthew H.
Published: January 2024

It has become increasingly apparent that even mature forests are susceptible to plant invasions. However, invasive plants are often more abundant in younger forest stands. It is difficult to disentangle possible mechanisms that would explain this pattern due to the scarcity of long-term studies in successional forests. Several mechanisms have been proposed to explain patterns of invasions as forests age, including biotic resistance, window of opportunity, historical legacies, and invasion debt. We explored patterns and potential mechanisms of plant invasions over 70-years in a regenerating forest with different land use histories in the Bolleswood Natural Area, Connecticut, USA. We examined how environmental factors related to colonization patterns of invasive and non-invasive introduced species over time, and whether these patterns were consistent with the proposed mechanisms. Non-invasive introduced species declined rapidly with forest development, while many invasive plants persisted or even increased over time as the forest aged. Colonization was focused in areas that were unforested when the study began, although this declined with time. Dispersal distance, soil conditions, and initial land cover played important roles in patterns of colonization, while the effect of shading was less clear. There was some evidence for each mechanism, but the relative importance of each mechanism was species-dependent, making generalizations about how invasive plants invade forests difficult. We found that land use history impacted invasion more strongly than forest age, but over time even mature forests were slowly being invaded by some species. Thus, invasive species management may be required even in mature forests.
Induction of Bacteriocin Production by Lacticaseibacillus rhamnosus Using the Co-culture Method
Authors: Khundrakpam Matilda , Kulkarni Padmashree , Bordoloi Sreya , Pani Somya
Published: January 2024

Background: - The rise of antibiotic-resistant bacterial strains in the past decade has led to research on the microorganisms in the human gut and their interactions with pathogenic counterparts. The human gut microbiome houses bacteria like Lactobacilli, which produces bioactive metabolites, called bacteriocins which are known for their antimicrobial activity against disease-causing microorganisms. However, their production is limited in monocultures which can be improved by introducing bacteriocinogenic pathogenic strains in the culture. To enhance bacteriocin production, we have co-cultured Lacticaseibacillus rhamnosus with Staphylococcus aureus, a pathogenic inducer strain in different media like MRS, proso millet modified media (PmMRS) [1], and foxtail millet modified media (FmMRS) [2].
Results: - Antimicrobial assays conducted on bacteriocin extracts revealed potent inhibitory effects against prevalent food-borne pathogenslike Staphylococcus aureus (MTCC[3] 1430), Shigella flexneri (MTCC1457) and Enterobacter cloacae (MTCC 509). The SEM analysis of the co-cultures corresponded to the results from the antimicrobial assay. The bacteriocin extract was analyzed using SDS-PAGE and MALDI-TOF analysis and it exhibited 58% sequence similarity with a translocase protein in Zymomonas mobilis subsp. Mobilis (ATCC31821) and 20% sequence similarity with a bioactive protein produced by Lactiplantibacillus plantarum WCFS5. Encapsulation of the extract in chitosan-based nanoparticles was pursued to enhance its antimicrobial effectiveness.
Conclusion: - While potential applications against foodborne pathogens and antibiotic-resistant bacteria are promising, further research, including purification and delivery optimization, is imperative for practical implementation. This work sheds light on harnessing microbial interactions and bioactive compounds for addressing antibiotic resistance challenges.
Comparative Research on Monitoring Methods for Nitrate Nitrogen Leaching in Tea Plantation Soils
Authors: zheng shenghong , Chai Hongling , Ning Qiuyan , Cheng Chen , He Weizhong , Shu Zaifa , Ni Kang , Ruan Jianyun
Published: January 2024

Background and aims Great concern has long been raised about nitrate leaching in cropland due to its possible environmental side effects in ground water contamination. we conducted a comparative study on monitoring methods for nitrate N leaching in tea plantation soils.Methods Here we employed two common techniques to measure nitrate leaching in tea plantation soils in subtropical China. Using drainage lysimeter as a reference method, the adaptability of estimating drainage and nitrate leaching by combining the water balance equation with the suction cup technique was investigated.Results The final cumulative leachate volume for the calculated and measured method was 721.43 mm and 729.92 mm respectively during the study period. Meanwhile, The cumulative nitrate leaching loss from the lysimeter and suction cup-based method was 47.45 kg ha− 1 and 43.58 kg ha− 1 under lysimeter nitrate concentrations ranging from 7 mg L− 1 to 13 mg L− 1, 156.28 kg ha− 1 and 79.95 kg ha− 1 under lysimeter nitrate concentrations exceeding 13 mg L− 1.Conclusion The suction cup-based method could be an alternative way of monitoring nitrate leaching loss within a certain range of nitrate concentrations in leachate. Besides, lower results occurred in suction cup samplers due to lack of representative samples which mainly leached via preferential flow when in strong leaching events. Thus, it is advisable to increase sampling frequency under such special conditions. The results of this experiment can serve as a reference and guidance for the application of ceramic cups in monitoring nitrogen and other nutrient-ion leaching in tea plantation soils.