bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN ANTARA TINGKAT SPIRITUAL DENGAN PERKEMBANGAN DIABETIC FOOT ULCER (DFU) DI KLINIK KITAMURA PONTIANAK
Authors: . Meiti Zahara
Published: April 2021

Latar Belakang : Diabetic foot ulcer (DFU) merupakan komplikasi dari diabetes Mellitus yangpaling sering terjadi dan semakin meningkat angka kejadiannya. Adanya kekuatan spiritual padadiri pasien dapat menjadi faktor penting dalam menguatkan pasien dalam menghadapipenyakitnya. Spiritualitas sangat berkaitan dengan koping individu, keyakinan dan praktik spiritualsangat membantu pasien dalam melakukan koping terhadap stres dan penyakit. Berdasarkan haltersebut, peneliti merasa perlu melihat hubungan antara tingkat spiritual dengan perkembangandiabetic foot ulcer (DFU) di Klinik Kitamura Pontianak. Tujuan : Mengetahui hubungan antaratingkat spiritual dan pekembangan diabetic foot ulcer (DFU) di Klinik Kitamura Pontianak.Metode : Penelitian kuantitatif dengan desain analitik korelatif dengan rancangan penelitiankohort prospektif dengan jumlah responden 31 orang. Pengumpulan data dilakukan dengankuesioner dan pendokumentasian gambar perkembangan luka. Analisis yang digunakanmenggunakan uji somers’d. Hasil : nilai r sebesar 0,217 dan nilai tersebut negatif sehinggamenunjukkan arah korelasi berlawanan, sedangkan nilai p didapat 0,184 Kesimpulan : Tidak adahubungan antara tingkat spiritual dan perkembangan DFU.Kata Kunci : diabetes mellitus, perkembangan diabetic foot ulcer, tingkat spiritual
PENGARUH PEMBERIAN TERAPI MUSIK KLASIK TERHADAP SKALA NYERI PADA IBU POST OPERASI SECTIO CAESAREA DI RSUD Dr. SOEDARSO KOTA PONTIANAK
Authors: . Winda Ayu Lestari
Published: April 2021

Latar Belakang : Sectio caesarea adalah suatu tindakan persalinan melalui pembedahan dengancara menyayat dinding perut dan dinding rahim untuk melahirkan janin yang pasti menimbulkannyeri. Salah satu upaya menurunkan nyeri bisa menggunakan terapi musik klasik. Hal ini menjadiketertarikan peneliti karena terapi musik klasik belum pernah dilakukan atau diberikan kepada ibupost sectio caesarea yang berada di RSUD Dr. Soedarso Kota Pontianak.Tujuan : Mengidentifikasi pengaruh pemberian terapi musik klasik terhadap skala nyeri pada ibupost sectio caesarea di RSUD Dr. Soedarso Kota Pontianak.Metode : Penelitian ini adalah penelitian Quasi Eksperimen Design dengan rancangan pre test andpost test nonequivalent control group. Sample penelitian adalah ibu post sectio caesarea yangterdiri dari 16 orang pada kelompok intervensi yang diberikan kombinasi analgesik dan terapimusik klasik dan 16 orang pada kelompok kontrol yang hanya diberikan analgesik serta diambildengan cara Accidental Sampling. Instrumen penelitian adalah lembar pre test dan post test skalaNumerik (Numerical Rating Scale atau NRS).Hasil : Hasil uji Wilcoxon menunjukkan ada penurunan tingkat nyeri yang signifikan sebelum dansesudah perlakuan pada kelompok intervensi yaitu p=0,002 (p<0,005) sedangkan pada kelompokkontrol tidak ada penurunan tingkat nyeri yang signifikan sebelum dan sesudah perlakuan yaitup=0,083, yang berarti ada perbedaan tingkat nyeri pada kelompok kontrol yang tidak diberikanterapi musik klasik dan kelompok intervensi yang diberikan terapi musik klasik.Kesimpulan :Ada pengaruh pemberian terapi musik klasik terhadap skala nyeri pada ibu postsectio caesarea di RSUD Dr. Soedarso Kota Pontianak.Kata Kunci : Nyeri, Ibu Post Sectio Caesarea, Terapi Musik KlasikReferensi : (2008-2018)
Pengaruh Terapi Relaksasi Zikir Dalam Menurunkan Nyeri Kepala Pada Pasien Hipertensi di Wilayah Kerja Upk Puskesmas Pal Tiga Kecamatan Pontianak Kota
Authors: . Erwin Setiawan
Published: April 2021

Latar Belakang: Nyeri kepala merupakan keluhan sangat umum terjadi pada pasiendengan hipertensi. Terapi zikir merupakan salah satu intervensi yang dipercaya untukmenurunkan tingkat stress pasien dan meningkatkan kenyamanan, sehingga nyeri kepalapasien dapat berkurang. Belum ada pemberian terapi spiritual seperti terapi zikir yangdilakukan di area kerja Puskesmas Pal 3 Pontianak.Tujuan: Mengetahui pengaruh terapi relaksasi zikir dalam menurunkan nyeri kepalapada pasien hipertensi di Puskesmas Pal 3 PontianakMetodologi: Menggunakan rancangan quasy-experimen dengan pre-post test controlledgrup. Pengambilan sampel dilakukan dengan purposive sampling dengan sampelberjumlah 20 pada masing-masing kelompok. Analisis data dengan uji Wilcoxon danMann-Whitney dengan nilai p ≤0,05Hasil: Karateristik responden rata-rata berusia 45-59 tahun (40.0%) dan berjenis kelaminlaki-laki (60.0%). Tingkat intensitas nyeri pada kelompok intervensi didapatkan nilai p =0,000 dengan nilai mean pretest= 2.90 dan postest = 2.10 juga kelompok kontrol didapatkan nilai p = 0,184 dengan nilai mean pretest= 2.95 dan postest = 3.00. Padaperbandingan intensitas nyeri antara kelompok intervensi dan kontrol bernilai p = 0,000.Kesimpulan: Terdapat perubahan intensitas nyeri kepala pasien hipertensi setelahdiberikan terapi zikir pada kelompok intervensi dan tidak terdapat perubahan nyeri kepalapasien pada kelompok kontrol. Terdapat perbedaan antara perubahan intensitas nyerikepala pasien hipertensi sehingga terapi zikir dapat dipertimbangkan untuk menjadiintervensi mandiri keperawatan dalam menangani masalah nyeri kepala pasien denganhipertensi.Kata kunci :Intensitas Nyeri, Hipertensi, Terapi ZzikirReferensi : 70 (2009-2018)
Hubungan Tingkat Kecemasan Dengan Kualitas Tidur Pada Mahasiswa Keperawatan Yang Sedang Mengerjakan Skripsi
Authors: Noor Hidayati Eka , Priyono Djoko , Anggraini Rara
Published: April 2021

Skripsi sebagai stressor yang tidak dapat dihindarkan oleh mahasiswa tingkat akhir yang dapat menimbulkan kecemasan. Kecemasan yang berkelanjutan  akan mempengaruhi kualitas tidur mahasiswa sehingga mengakibatkan gangguan keseimbangan fisiologis dan psikologis. Keadaan ini akan berpengaruh pada penurunan akademik yaitu hasil penyusunan skripsi menjadi kurang maksimal.Tujuan: untuk menganalisis hubungan antara tingkat kecemasan dengan kualitas tidur pada mahasiswa keperawatan yang megerjakan skripsi di pontianak. Metode: Penelitian kuantitatif menggunakan desain observasional analitik denganndengan metode purposive sampling. Responden pada penelitian ini sebanyak 98 orang. Pengukuran dilakukan dengan kuesioner Hamilton Anxiety Rating Scale (HARS) dan kuesioner Pittsburgh Sleep Quality Index (PSQI). Analisis statistik menggunakan uji fisher.Hasil: Jumlah usia terbanyak yaitu 21 tahun sebesar 57,1% dengan jenis kelamin perempuan sebesar 74,5%. Hasil analisis uji fisher menunjukan  nilai p = 0,036 yang berati p < 0,05.Kesimpulan: Ada hubungan antara tingkat kecemasan dengan kualitas tidur pada mahasiswa keperawatan yang sedang mengerjakan skripsi di pontianak.
Electrostatic Regulation of Blue Copper Sites
Authors: Bím Daniel , Alexandrova Anastassia N.
Published: April 2021

In the last 50 years, the blue copper proteins became central targets of investigation. Extensive experiments focused on the first- and second-coordination spheres of Cu to probe the effect of local perturbations on its properties. We found that local electric fields, generated by charged residues evolutionarily placed throughout the protein edifice, constitute an additional significant factor regulating blue copper proteins. These fields are not random, but exhibit a highly specific directionality, negative with respect to Cu-SCys and Cu-SMet in the Cu first shell. The field magnitude contributes to fine-tuning of the geometric and electronic properties of Cu sites in individual blue copper proteins. Specifically, the local electric fields evidently control the Cu-SMet bond distance, Cu(II)-SCys bond covalency, and the energies of the frontier molecular orbitals, which, in turn, govern the Cu(II/I) reduction potential and the relative absorption intensities at 450 nm and 600 nm.
Protein Dynamics and Substrate Protonation State Mediate the Catalytic Action of Trans-4-Hydroxy-L-Proline Dehydratase
Authors: Yang Zhongyue , Kulik Heather
Published: April 2021

The enzyme trans-4-Hydroxy-L-proline (Hyp) dehydratase (HypD) is among the most abundant glycyl radical enzymes (GREs) in the healthy human gut microbiome and is considered a promising antibiotic target for the prominent antibiotic-resistant pathogen Clostridium difficile. Although an enzymatic mechanism has been proposed, the role of the greater HypD protein environment in mediating radical reactivity is not well understood. To fill this gap in understanding, we investigate HypD across multiple time- and length- scales using electronic structure modeling and classical molecular dynamics. We observe that the Hyp substrate protonation state significantly alters both its enzyme-free reactivity and its dynamics within the enzyme active site. Accurate coupled cluster modeling suggests the deprotonated form of Hyp to be the most reactive protonation state for C5–Hpro-S activation. In the protein environment, hydrophobic interactions modulate the positioning of Cys434 radical to enhance the reactivity of C5–Hpro-S abstraction. Long-time dynamics reveal that changing Hyp protonation states triggers the switching of a Leu643-gated water tunnel, a functional feature that has not yet been observed for members of the GRE superfamily.
Synthesis of a Highly Aromatic and Planar [10]Annulene
Authors: Parmar Karnjit , Blaquiere Christa S. , Lukan Brianna , Gengler Sydnie , Gravel Michel
Published: April 2021

As the next neutral structure following Hückels rule, a planar and aromatic [10]annulene is ideal to study the link between ring size and aromaticity. However, the puckered geometry of the parent [10]annulene suggests that the aromatic stabilization energy is not sufficient to overcome the ring strain that exists when the system is forced into planarity. It has been shown computationally that this ring strain can be alleviated through the addition of two or more cyclopropane rings to the periphery, thereby creating theoretically aromatic structures. An alternative strategy to eliminating the issue of ring strain was demonstrated experimentally with the successful preparation of the highly aromatic 1,6-didehydro[10]annulene. However, the system rapidly cyclizes at -40°C to a naphthalene diradical due to the close proximity of the in-plane p-orbitals present in the system. Here we show that cyclopropanating one side of the unstable annulene successfully prevents the destabilizing cross-ring interaction while maintaining a highly aromatic structure. Remarkably, the formed [10]annulene is bench stable and can be stored for extended periods of time.
Formulation and Characterization of Glibenclamide Solid Lipid Submicroparticles Formated by Virgin Coconut Oil and Solid Matrix Surfactant
Authors: Mardiyanto Mardiyanto , Fithri Najma Annuria , Amriani Annisa , Herlina Herlina , Sari Dwi Purnama
Published: April 2021

Glibenclamide has the biopharmaceutics classification system (BCS) class II which has high permeability and low solubility. The solubility of glibenclamide can be enhanced by forming solid lipid nanoparticles (SLN). This research has the aim to prepare and characterize SLN loading glibenclamide. The glibenclamide SLN formula was composed by using the liquid lipid as virgin coconut oil (VCO), PEG 6000 as a solid matrix, tween 80 with various concentrations as a stabilizer, and PEG 400 as co-surfactant. Characterization was conducted by determining the encapsulation efficiency (%EE), size measurement, particle size distribution, and zeta potential of SLN glibenclamide. SLN formation was also tested for its physical stability based on the heating-cooling cycle method. The optimum formula was obtained at the concentration of tween-80 of 1 mg/mL yielding the %EE value of 60.6194%, and pH 6.01. The results of particles diameter analysis were 175.5 ± 10.07 nm with a polydispersity index (PDI) of 0.1270, and zeta potential of +5.9 mV respectively. Stability testing by the heating-cooling cycle method has shown the instability of the SLN glibenclamide form under extreme temperatures and mechanics. It could be concluded that the results of characterization of glibenclamide SLN showed appropriate physical properties for nanoparticulate formulation.
Structural Stability of Ni/Al Layered Double Hydroxide Supported on Graphite and Biochar Toward Adorption of Congo Red
Authors: Siregar Patimah Mega Syah Bahar Nur , Palapa Neza Rahayu , Wijaya Alfan , Fitri Erni Salasia , Lesbani Aldes
Published: April 2021

In this research, Ni/Al layered double hydroxide (LDH) was modified by using co-precipitation method to generate Ni/Al-graphite (Ni/Al-GF) and Ni/Al-biochar (Ni/Al-BC). The adsorbents were applied to remove Congo Red from aqueous solution. The obtained samples were characterized by using XRD, FTIR, BET and TG-DTA. The XRD diffraction pattern of Ni/Al LDH, Ni/Al-GF, and Ni/Al-BC presented the formation of composite with decreasing crystallinity. The surface area modified LDHs was higher than the pristine materials, which was obtained 15.106 m2/g, 21.595 m2/g and 438.942 m2/g for Ni/Al-LDH, Ni/Al-GF, Ni/Al-BC respectively. The adsorption of Congo Red on the materials was tested at diferent parameters and the results exhibited that Congo Red adsorption on LDHs were pseudo-first-order (PFO) kinetic, spontaneous, endothermic and followed Langmuir model. The adsorbents removed Congo Red by high performance stability with adsorption capacity was 116.297 mg/g for Ni/Al-GF and 312.500 mg/g for Ni/Al-BC. These adsorption capacity was higher than the pristine LDH (61.728 mg/g). The regeneration process which carried out for five cycles showed that Ni/Al-GF and Ni/Al-BC have stable structures as reuse adsorbents for Congo Red from aqueous solution.
Urban Environment and the Air Temperature Trend: The Case of the Metropolis of Brazilian Amazon
Authors: Dias Thaiane Soeiro da Silva , De Souza Everaldo Barreiros , Franco Vânia dos Santos , Almeida Pinto Álvaro José de , Thales Marcelo Cordeiro , Mendoza Ronaldo Rosales , Amaral Calil Torres , Gonçalves Juliana Belmiro , Lima Ilale Ferreira , Pfeiff Greicy Kelly , Ribeiro Junior Júlio Pereira , Da Silva Marcus Vinicius Silva
Published: April 2021

Temperature is the focus of many studies around the world due to several factors, such as population growth and land use and coverage changes, as these elements contribute to the increase/decrease of air temperature on the surface of a region. This study aimed to analyze the temperature trend in the metropolises of the Brazilian Amazon (Belém and Manaus), from 1978 to 2018, for the dry and rainy regimes, taking into account population growth and the change in land use and coverage of referred cities. For this purpose, monthly data of maximum, compensated and minimum temperature in a radius of 25 km from the coordinates of the meteorological stations of each city were used, extracted from the National Institute of Meteorology, usage data and coverage of the Annual Soil Coverage and Use Mapping Project in Brazil and population data of the Brazilian Institute of Geography and Statistics. The results showed a positive trend in the temperature of these regions studied, due to the increase in urban infrastructure and population growth, as well as a decrease in forest formation in the metropolises of the Brazilian Amazon  Ambiente Urbano e a Tendência da Temperatura do Ar: O Caso das Metrópoles da Amazônia BrasileiraR E S U M OA temperatura é foco de muitos estudos em todo o mundo devido a vários fatores, como por exemplo, crescimento da população e mudanças de uso e cobertura do solo, pois tais elementos contribuem para o aumento e/ou diminuição da temperatura do ar em superfície de uma região. Neste estudo buscou-se analisar a tendência da temperatura nas metrópoles da Amazônia brasileira (Belém e Manaus), no período de 1978 a 2018, para os regimes seco e chuvoso, levando em consideração o crescimento populacional e a mudança de uso e cobertura do solo das referidas cidades. Para tal, utilizaram-se dados mensais de temperatura máxima, compensada e mínima em um raio de 25 km a partir das coordenadas das estações meteorológicas de cada cidade, extraídos do Instituto Nacional de Meteorologia, dados de uso e cobertura do Projeto de Mapeamento Anual da Cobertura e Uso do Solo no Brasil e dados populacionais do Instituto Brasileiro de Geografia e Estatística. Os resultados mostraram uma tendência positiva na temperatura das referidas regiões estudadas devido ao aumento da infraestrutura urbana e crescimento populacional, bem como uma diminuição da formação florestal nas metrópoles da Amazônia brasileira.Palavras-chave: Uso e cobertura do solo, Crescimento populacional, Temperatura
IMPLEMENTATION OF THE ACADEMIC INTEGRITY PRINCIPLES AT THE UNIVERSITY: EXPERIENCE OF CONDUCTING EDUCOLOGICAL DEBATES
Authors: Khanykina Nataliia , Sopova Dana , Bulvinska Oksana
Published: April 2021

The article analyzes the experience of introducing academic integrity on the example of an intellectual educational game – a debate at the Borys Grinchenko Kyiv University. Such work has become traditional for the University residents on the basis of the educational circle «Educological Discourse» of the Research Laboratory of Educology and the Pedagogical Institute of the University. The purpose of the scientific article is to present the experience of conducting Educological debates on the introduction of academic integrity and their impact on improving the quality of higher education. The theoretical basis of the «Educological Debate» is the scientific direction of integrated research in the field of education – Educology, which is a synergy of such educational sciences as philosophy of education, history of education, educational policy, educational law, education management, economics of education, sociology of education, cultural education. These educational sciences make up the content of educational training, provide an opportunity to analyze and reveal various aspects of academic integrity. The «Educological debates» have polemical nature. The teams are able to demonstrate the main areas of work during the «Educological Debates». The principles, mechanisms of academic integrity introduction which can improve quality of education are resulted. The role of meetings in the format of an intellectual educational game is emphasized. The game serves as an impetus for awareness and desire to continue working on the creation and search for tools and mechanisms for the academic integrity introduction in the academic space. The conclusions of this work on the importance of informing students about the normative and legal, moral and ethical principles of combating plagiarism, teaching students the rules of ethical behavior in the academic environment are made. It is mentioned about the interactive teaching method of debates, which is effective for the development of both professional and general competencies of students. It helps to increase the level of critical thinking and communication skills.
ANALYSIS AND EVALUATION OF QUALITATIVE AND QUANTITATIVE INDICATORS OF INFORMATION WHEN SOLVING PROBLEMS OF CONSTRUCTION SYSTEMS OF DATA TRANSMISSION AND TRANSFORMATION
Authors: Zaharchenko Mikola , Hadzhyiev Matin , Salmanov Nariman , Shvets Natalya , Havel Sergey
Published: April 2021

The clarification of the concept of information only slightly supplements the intuitive understanding of this term and does not provide anything for the construction of a quantitative theory of information that could be used in solving engineering problems. For such a theory, it is necessary to introduce an "operational" definition of this concept, which is based on an indication of the measurement method. To estimate the amount of information received, it is necessary to find a measure of the uncertainty of a particular situation. When transmitting information over a distance, at the output of the transmitting converter there is a finite system of signals that unambiguously correspond to the symbols and form the input alphabet of the communication channel. At the output of the receiving device, there is a finite system of signals that form the output alphabet of the communication channel. The process of transmitting information consists in selecting chips, sending them over the communication line and making a decision on the transmitted signal based on the received chip. It is obvious that the extraction of information about signals from signals is associated with the representation of the alphabets {X} and {Z} in the form of a combined set {XZ}. The transfer of information in communication systems is always associated with a change at the receiver of information about the actually transmitted signals. From the point of view of the receiver, the alphabet of the source has uncertainty, since he can only know a priori probabilities, but it is not known whether the signal was actually transmitted; this can be judged only by the magnitude of the posterior probabilities. From this point of view, setting some numerical characteristics of a random variable is not enough. This article analyzes the issues of reliability of events in the "ensemble" of received messages, depending on the a priori probabilities of events. The assessment of the amount of information in relation to the reliability of the received messages is made, the recommendations used in solving majority of the problems associated with the construction of information transmission and transformation systems are indicated.
Impact of Globalization on Major Macroeconomic Variables: Empirical Evidence from Pakistan
Authors: Mumtaz Syra , Younas Muhammad Zeeshan
Published: April 2021

Globalization is a multi-dimensional phenomena with profound impact on different aspects of the modern world, including economic, social, political, cultural, environmental, and geographical. This study is an attempt to analyze how various components of globalization, i.e., trade openness, financial liberalization and labor mobility impacts the economic dynamics of a developing country affecting the performance of macroeconomic variables including the budget deficit, inflation and economic growth. In this study, we use the terms trade openness and liberalization along with financial openness, financial liberalization and financial development interchangeably. The purpose is to capture the overall impact irrespective of nature as nature may lead to contradictory results. Furthermore, the labour flows give due attention as human capital is an inevitable avenue for the effective and sustainable growth of any country. It is noticed that various global factors effect budget deficits, inflation and economic growth with varying intensities depending upon the size and dynamics of the economy. The empirical analysis involves the time series data of Pakistan from 1973 to 2014. The autoregressive distributed lag (ARDL) methodology is used to obtain the results and policy related suggestions.
ANALISIS GENDER PADA KEBERHASILAN PROGRAM KAMPUNG KELUARGA BERENCANA (KB)
Authors: Liandra Vallenxena
Published: April 2021

Program Kampung KB adalah miniatur pelaksanaan program KB secara terpadu dan komprehensif di tingkat desa maupun dusun. Adanya Kampung KB ini dapat meningkatkan capaian KB aktif dan kesejahteraan desa maupun dusun. Tujuan penelitian ini adalah untuk: 1) menggambarkan tingkat pembagian kerja pada rumahtangga peserta program Kampung KB, 2) melihat wujud kesetaraan dan keadilan gender pada program Kampung KB, khususnya Kampung KB Jasem, dan 3) menganalisis  hubungan antara tingkat pembagian kerja pada rumahtangga peserta program Kampung KB dengan tingkat kesetaraan dan keadilan gender pada program tersebut, serta 4) menganalisis hubungan antara tingkat kesetaraan dan keadilan gender pada program Kampung KB dengan tingkat keberhasilannya. Penelitian ini dilaksanakan di Kampung KB Jasem, DI Yogyakarta dengan unit analisis rumahtangga Pasangan Usia Subur sebanyak 50 rumahtangga yang dipilih menggunakan teknik simple random sampling. Uji korelasi menggunakan Rank Spearman menunjukkan bahwa terdapat hubungan antara tingkat pembagian kerja pada rumahtangga peserta program Kampung KB dengan tingkat kesetaraan dan keadilan gender pada program tersebut, namun tidak ada hubungan antara tingkat kesetaraan dan keadilan gender pada program Kampung KB dengan tingkat keberhasilannya.

Kata Kunci: Keberhasilan program, Kesetaraan dan keadilan gender, Program Kampung KB
PENATAAN KAWASAN EMBUNG AIK BUAL MELALUI PENGUATAN MEDIA INTERPRETASI WISATA
Authors: Syaputra Maiser
Published: April 2021

Sarana interpretasi kepariwisataan adalah semua fasilitas informasi yang memungkinkan agar aktivitas kepariwisataan dapat hidup dan berkembang serta dapat memberikan pelayanan pada wisatawan untuk memenuhi kebutuhan informasi yang beraneka ragam. Sarana interpretasi wisata juga dapat diartikan sebagai bagian kelengkapan daerah tujuan wisata yang diperlukan untuk melayani kebutuhan informasi wisatawan dalam menikmati perjalanan wisatanya.Pembangunan sarana interpretasi wisata di daerah tujuan wisata maupun objek wisata tertentu harus disesuaikan dengan kebutuhan wisatawan baik secara kuantitatif maupun kualitatif. Sarana wisata secara kuantitatif menunjuk pada jumlah sarana wisata yang harus disediakan, dan secara kualitatif yang menunjukkan pada mutu informasi yang diberikan dan yang tercermin pada kepuasan wisatawan yang memperoleh pelayanan informasi. Dalam hubungannya dengan jenis sarana interpretasi wisata di daerah tujuan wisata khususnya kawasan hutan telah disusun suatu standar kebutuhan yang baku, sehingga pemegang ijin atau penyedia sarana wisata tinggal memilih atau menentukan jenis sarana yang akan disediakannya, hal ini tercantum dalam Perdirjen PHKA No.5 tahun 2015 meliputi papan informasi, papan interpretasi, papan peringatan, dan papan petunjuk arah. Penataan kawasan embung Aik bual melalui penguatan media interpretasi wisata dilakukan melalui beberapa rangkaian kegiatan, diawali dengan obeservasi potensi kawasan dan wawancara terhadap aktor kunci, diikuti dengan menyelenggarakan penyuluhan bersama pengelola mengenai teknik pembuatan media interpretasi serta diakhiri dengan pendampingan pembuatan materi media interpretasi.________________________________Kata kunci: penataan, interpretasi, aik bual
OPTIMALISASI PENGEMBANGAN EKONOMI LOKAL (PEL) BERBASIS SUMBER DAYA LAUT PERIKANAN DI DESA MALAKA, KECAMATAN PEMENANG MELALUI EDUKASI DAN PENDAMPINGAN PENGOLAHAN IKAN HASIL TANGKAPAN NELAYAN
Authors: Febry Aulia
Published: April 2021

ABSTRAK            Desa Malaka, Kecamatan Pemenang, merupakan salah satu desa yang penduduknya sebagian besar bekerja sebagai nelayan di Kabupaten Lombok Utara. Kendala yang dihadapi oleh masyarakat adalah hasil tangkapan yang diperoleh nelayan dijual pada tengkulak dengan harga murah. Alternatif solusi yang dapat dilakukan untuk mengatasi kendala tersebut adalah dengan mengadakan edukasi dan pendampingan pengolahan ikan hasil tangkapan nelayan. Tujuan dari program ini adalah memberikan edukasi kepada masyarakan Desa Malaka dan melakukan pendampingan pengolahan ikan hasil tangkapan nelayan menjadi abon ikan. Metode yang digunakan adalah persiapan program, sosialisasi dan pelatihan, pembuatan produk, pemanfaatan, monitoring, dan mengevaluasi. Hasil dari program tersebut adalah kelompok pengolahan dan pemasaran yang berpotensi menghasilkan abon ikan tongkol Malaka atau meningkatkan nilai jual produk sehingga masyarakat dapat memproduksi hasil olahan sumber daya laut yang memiliki nilai ekonomi tinggi untuk meningkatkan perekonomian masyarakat.Kata Kunci : Nelayan, Ikan Tongkol, Abon
GERAKAN SELF CONTROL PENYAKIT DEGENERATIF DI DESA GONDANG LOMBOK UTARA
Authors: Hamdin Candra Dwipayana , Muliasari Handa
Published: April 2021

Penyakit degeneratif merupakan penyakit yang disebabkan oleh menurunnya kemampuan sel dibandingkan normal akibat penambahan usia. Kondisi degeneratif dipercepat oleh banyak faktor, salah satunya yang bisa dikendalikan adalah gaya hidup. Penyakit degeneratif merupakan penyebab kematian terbesar di dunia dikarenakan penderita baru menyadari setelah terjadi komplikasi. Hal tersebut karena penyakit degeneratif gejalanya tidak terlihat jelas sehingga sering disebut The Silent Killer. Guna meningkatkan kesadaran masyarakat terhadap penyakit degenerative, maka penting untuk dilakukan edukasi kepada masyarakat terkait bagaimana pencegahan, tanda dan gejala serta bagaimana perawatannya. Pengabdian ini bertujuan untuk memberikan pemahaman kepada masyarakat terkait penyakit degeneratif dan membentuk kelompok masyarakat sebagai agen edukator. Pengabdian masyarakat dilaksanakan di Dusun Karang Kates, Desa Gondang dengan jumlah 40 peserta. Dari hasil pretest ditunjukkan dengan hasil jawaban benar 50% dari keseluruhan menunjukkan kurangnya pengetahuan masyarakat terkait penyakit degeneratif. Setelah kegiatan diskusi dilakukan postest sebagai tolak ukur daya tangkap peserta. Hasil postest menunjukkan peningkatan pengetahuan dan wawasan terkait penyakit degeratif yaitu 95% jawaban benar. Selain itu telah terbentuk kelompok yang berkomitment sebagai agen edukator dari, oleh dan untuk masyarakat. Dalam jangka panjang diharapkan menjadi Pusat Edukasi Kesehatan Masyarakat.
PEMANFAATAN LIMBAH TERNAK SAPI BERBASIS “AGRIBUSSINES PRODUCT” DI DESA PERINA KECAMATAN JONGGAT KABUPATEN LOMBOK TENGAH
Authors: Soadikin Muhammad , Husna Novanita Laylatul , Jupri Ahmad
Published: April 2021

ABSTRAK. Masyarakat di Desa Perine kebanyakan memelihara ternak sapi dan ikan, namun belum mengetahui cara mengolah limbah berupa kotoran atau fesses sapi untuk dijadikan sebagai pupuk organik padat (kompos). Padahal agar dapat memberikan manfaat yang maksimal, maka hasil sampingan pemeliharaan ternak sapi tersebut harus diproses sebelum dipergunakan sebagai pupuk. Umumnya proses pengolahan dimaksud terdiri dari dua kelompok, yakni pengolahan secara terbuka dan tertutup. Pada kegiatan ini telah dilakukan pengolahan feses sapi untuk digunakan sebagai pupuk organik untuk digunakan langsung oleh petani. Untuk itu, kegiatan ini diharapkan dapat meningkatkan kemandirian petani dalam memenuhi kebutuhan sendiri untuk berbagai keperluan dalam pertanian. ______________________Kata kunci: pupuk, kompos, sapi, urea molases blok (UMB) ABSTRACT. Communities in Perine Village mostly raise cattle and fish, but do not yet know how to process waste in the form of cow dung or fesses to be used as solid organic fertilizer (compost). Even though in order to provide maximum benefits, the byproducts of raising cattle must be processed before being used as fertilizer. Generally, the said processing consists of two groups, namely open and closed processing. In this activity cattle processing has been carried out to be used as organic fertilizer for direct use by farmers. Therefore, this activity is expected to increase the independence of farmers in meeting their own needs for various purposes in agriculture. ______________________Keywords: fertilizer, compost, cattle, urea molasses block (UMB)
WORKSHOP APPLICATION OF EXPERIMENTAL METHODS IN BIOLOGICAL LEARNING FOR MADRASAH TEACHERS IN WEST LOMBOK
Authors: Sukiman Sukiman , Rohyani Immy Suci , Sukenti Kurniasih , Aryanti Evy
Published: April 2021

There are several learning models that are applied in learning Biology in secondary schools. The teaching and learning process in several schools is still dominated by the lecture method. This community service activity aims to improve the knowledge and skills of Madrasah Teachers in West Lombok Regency in applying experimental methods for learning biology on the subject of photosynthesis. The methods used in community service activities are: lectures and discussions,  practice photosynthesis experiments, and independent assignments in the form of making learning media. This community service activity was attended by 20 participants consisting of Madrasah teachers from West Lombok Regency. This activity received a positive response from the target participants. This activity has succeeded in increasing participants' knowledge and skills regarding the subject of photosynthesis and experimental methods for learning photosynthesis.
PEMBERDAYAAN RUMAH CERDAS UNIVET (RCU) BUNAYYA DI DESA JETIS SUKOHARJO
Authors: Suswandari Meidawati , Widayanti Erma Dwi
Published: April 2021

Tujuan pengabdian ini adalah 1) untuk membantu siswa dalam mendampingi belajar dari rumah selama masa pandemic Covid-19, dan 2) untuk memberdayakan Rumah Cerdas Univet (RCU) di Desa Jetis Sukoharjo. Metode pengabdian ini dilakukan melalui 4 tahapan, yaitu sosialisasi, pelaksanaan, pendampingan, dan evaluasi. Pengabdian ini dilakukan di Ngabean  RT 02 RW 01, Desa Jetis, Sukoharjo. Sasaran pemberdayaan Rumah Cerdas Univet ini yaitu siswa Taman Kanak-Kanak (TK) dan siswa Sekolah Dasar (SD) dengan jumlah 5 orang.  Hasil pengabdian menunjukan bahwa 1) untuk membantu siswa dalam mendampingi belajar dari rumah selama masa pandemic Covid-19 yaitu berjalannya RCU Bunayya dengan aktivitas bimbingan belajar berjalan dengan baik dan tidak ada kendala. Hal ini terlihat dari mahasiswa yang terlibat dalam kegiatan RCU Univet Bunayya dan dapat membantu guru dalam melaksanakan pembelajaran selama pandemi covid-19. Disisilain evaluasi hasil belajar siswa diperoleh bahwa siswa merasa senang dan menyukai pembelajaran (bimbingan belajar) oleh kakak-kakak mahasiswa KKN Univet Bantara.  2) untuk memberdayakan Rumah Cerdas Univet (RCU) di Desa Jetis Sukoharjo dengan 4 tahapan, antara lain: (a) tahap Sosialisasi, meliputi pengenalan ruang lingkup Rumah Cerdas Univet Bunayya serta memberi dukungan bagi guru, peserta didik, dan pihak sekolah dalam beradaptasi melalui penerapan dan penggunaan teknologi untuk mendukung kegiatan belajar di rumah. (b) Tahap Pelaksanaan, proses bimbingan belajar di RCU Bunayya pelaksanaanya dilakukan oleh mahasiswa KKN dalam bentuk bimbingan belajar di rumah setiap hari Selasa dan Jumat pukul 13.00-14.00 WIB. (c) Tahap Pendampingan, pelaksanaan pendampingan pembelajaran juga mengikuti protocol kesehatan. (d) Tahap Evaluasi, mahasiswa KKN melaksanakan program kerja RCU Bunayya dengan baik hal ini terlihat pula hasil belajar siswa/anak baik dalam bentuk nilai skor soal penugasan.
Diagnostic accuracy of kidney shear wave elastography at the diagnosis of ureteral stones
Authors: YILDIRIM Utku Mahir , ŞAHİN Erkan , SOLAK Aynur , ÖRS Bumin , SERTER Selim
Published: April 2021

Aim: To determine the efficacy of kidney shear wave elastography (SWE) in patients diagnosed with ureteral stones.Method: Both kidneys of 30 patients were evaluated prospectively with SWE. The ureteral stone size and the degree of hydronephrosis were determined by sonographic examination. The contralateral kidney was accepted as the control parameter. Stone size, grade of hydronephrosis and kidney shear wave speed changes were noted and their relations were examined for statistical significance.Results: Affected kidney group had significantly increased SWE values than the control group. (3.87+-1.22 vs 2.06+-0.72 m/sec) (p=0.01). Neither the stone size nor the kidney SWE values showed a correlation with the gender. There was a positive correlation between the grade of hydronephrosis and the stone size (p=0.047, r=0,36). Kidneys with grade 2 hydronephrosis had significantly higher SWE values than those with grade 1 hydronephrosis.Conclusion: SWE is a promising tool to observe the parenchymal elasticity changes in patients with hydronephrosis secondary to ureteral stones. Further studies are necessary to confirm the research results.
The relationship between the changes in inflammatory parameters and response to treatment in major depression patients starting antidepressant treatment
Authors: UYGUR Abdullah Burak , ÇANKAYA Şeyda
Published: April 2021

Aim: Changes in inflammatory parameters such as cytokines, stress hormones and C reactive protein that occur in depression, are important in understanding the pathophysiology of depression and developing new treatment approaches. The main purpose of this study was to determine the changes in inflammatory markers in patients with major depression, before and after antidepressant treatment, as well as to determine the effect of antidepressant treatment types on these changes.Methods: This study was a single center, retrospective study. According to the retrospective records of the last five years in the psychiatry outpatient clinic of Alanya Alaaddin Keykubat University Training and Research Hospital, the patients diagnosed with Major Depressive Disorder (MDD), started on single antidepressant treatment for the first time and who used antidepressant treatment for at least 6-8 weeks, were included in the study. Patients whose Hamilton Depression Rating Scale (HDRS), complete blood count, C reactive protein and cortisol values were reached from the system during MDD treatment, constituted the sample of the study.Results: In the present study, after the antidepressant treatment, while HDRS scores decreased significantly in patients with Major Depression compared to before treatment (p<0,001), no significant correlation was found between the changes in inflammatory parameters and the response to treatment (p>0,05). This condition was independent of the type of antidepressant used in the treatment (p>0,05 in the SSRI treatment group, p>0,05 in the SNRI treatment group). In addition, it was observed that the decrease in depression scores was not associated with the type of antidepressant (p=0,001, in the SSRI treatment group, p=0,005, in the SNRI treatment group).Conclusion: Results to support the inflammatory hypothesis in Major Depressive Disorder were not conclusive in this study. Considering that the pathophysiology of depression is quite complex, it could be argued that a single group of blood tests may not be sufficient to explain the link between inflammation and depression. Considering all the limitations of the study, a future a prospective study to prove the inflammatory hypothesis in MDD, including the detailed blood, BOS tests, along with more comprehensive neuroimaging parameters on the brain pathways, might provide more effective results.
Optimization of searching for moving targets of a multifunctional radar station
Authors: Піскунов С.М. , Роменський Д.С. , Бабич В.Ю.
Published: April 2021

A method for optimizing the process of searching for an unknown number of moving targets in conditions of stochastic uncertainty is proposed, which allows to significantly reduce the average time of their finding by a multifunctional radar device equipped with an antenna array. More effective is the optimal managed search, in which the order of viewing different directions is determined in the search process depending on the results of already performed views. One of the important areas of further improvement of radar technology is the transition to antenna arrays with digital beamforming based on adaptive signal processing directly in the elements of the digital antenna array (DAA).
ARTIKEL KONSEP EKONOMI PADA MASA MERKANTILISME
Authors: septiani Dian
Published: April 2021

Untuk mengetahui konsep ekonomi pada masa merkantilisme
Differential expression of NR3C2 in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding nuclear receptor subfamily 3 group C member 2, NR3C2, when comparing primary tumors of the breast to the tissue of origin, the normal breast. NR3C2 mRNA was present at significantly lower quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of NR3C2 in primary tumors of the breast was correlated with distant metastasis-free survival in patients with luminal A subtype cancers, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by molecular subtype. NR3C2 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Sistem Ekonomi Laissez Faire
Authors: Hendra Samsul
Published: April 2021

Laissez Faire berarti serahkan semua kegiatan ekonomi kepada pasar
INOVASI PENDIDIKAN (PROFESIONALISME GURU)
Authors: amelia weni
Published: April 2021

Seiring dengan perubahan pada abad 21 ini demikian mendorongnya sebuah inovasi. Setiap pemecahan masalah kerap kali jalan keluarnya memerlukan solusi, hasil pemikiran yang berulang dengan upaya penyelesaian masalah menuju pembaharuan atau perbaikan. Dengan ini gagasan maupun ide dapat menciptakan inovasi. Tetapi pada dasarnya inovasi, terutama dalam dunia pendidikan dengan komponen pendidikan dasarnya bertujuan untuk mengubah kehidupan manusia agar menjadi lebih baik dari sebelumnya. Berangkat dari masalah tersebut inovasi semakin dibutuhkan, menunjukan betapa pentingnya upaya pembaharuan. Inovasi dalam proses pembelajaran, guru menentukan bagaimana materi ajar tersampaikan, bagaimana peran guru, bagaimana peran siswa, apa sumber daya pembelajaran yang dapat digunakan, dan bagaimana memfungsikan semuanya dalam kegiatan pembelajaran di kelas dalam strategi pembelajaran berbasis teknologi informasi diera sekarang ini. Didalam suatu bangsa pendidikan sebagai acuan yang mengarah atau menandakan berkembangnya negara tersebut. Majunya suatu negara tergantung kualitas pendidkan, mutu pendidikan dilihat dari seberapa cakapnya sesorang dalam menghadapi globalisasi saat ini.
Teknologi Informasi Dalam Mengembangkan Inovasi Pendidikan
Authors: Abdurrahman Luthfi
Published: April 2021

Kata inovasi berasal dari bahasa Inggris yaitu innovation yang bermakna segala hal yang baru atau pembaharuan. Kata inovasi dalam Kamus Besar Bahasa Indonesia dimaknai sebagai pemasukan atau pengenalan hal-hal yang baru, penemuan baru yang berbeda dari yang sudah ada atau sudah dikenal sebelumnya (gagasan, metode atau alat). Biasanya pada inovasi, perubahan-perubahan terjadi hanya menyangkut aspek-aspek tertentu, dalam arti smepit dan terbatas. Sementara dalam pembaruan biasanya perubahan terjadi adalah menyangkut berbagai aspek, bahkan tidak menutup kemungkinan terjadi perubahan secara total atau keseluruhan. Jadi ruang lingkup pembaruan pada dasarnya lebih luas. Dalam inovasi Pendidikan, secara umum ada dua buah model inovasi yang baru yaitu, yang pertama top- dwon model, inovasi Pendidikan yang diciptakan oleh pihak tertentu berbagai pimpinan atau atasan yang diterapkan kepada bawahan. Yang kedua Bottom up model, yaitu model inovasi yang bersumber dan hasil ciptaan dari bawah dan dilaksanakan sebagai upaya untuk meningkatkan mutu proses penyelenggaraan dan hasil pendidikan. Guru mempunyai peranan yang amat strategis dan urgen dalam keseluruhan upaya Pendidikan. Media modern tidak lepas dari teknologi. Suatu pembelajaran dikatakan efektif apabila telah mencapai tujuan dimana siswa dapat mengasah keterampilan berpikir dan memperoleh sejumlah pengetahuan yang bermanfaat baginya (Susanto,dkk. 2021: 73).
Uts inovasi pendidikan
Authors: adam Donny
Published: April 2021

Inovasi pendidikan merupakan perubahan baru dan berbeda dalam kualitas Sengaja berusaha meningkatkan kemampuan Untuk mencapai tujuan pendidikan tertentu. Pemanfaatan teknologi berupa inovasi dalam pendidikan Apalagi di era Revolusi Industri 4.0. Metode penelitian adalah metodevKualitatif. Hasil penelitian yang dilakukan menunjukkan bahwa terdapat banyak model internal Menerapkan inovasi pendidikan termasuk konsep perubahan, memberikan saran untuk perubahan, Mengadopsi dan menerapkan.
Consensus-based guidance for conducting and reporting multi-analyst studies
Authors: Aczel Balazs , Szaszi Barnabas , Nilsonne Gustav , Van den Akker Olmo , Albers Casper J , van Assen Marcel A. L. M. , Bastiaansen Jojanneke A. , Benjamin Daniel Jacob , Boehm Udo , Botvinik-Nezer Rotem , Bringmann Laura Francina , Busch Niko , Caruyer Emmanuel , Cataldo Andrea Michael , Cowan Nelson , Delios Andrew , van Dongen Noah N'Djaye Nikolai , Donkin Chris , van Doorn Johnny , Dreber Anna , Dutilh Gilles , Egan Gary F. , Gernsbacher Morton Ann , Hoekstra Rink , Hoffmann Sabine , Holzmeister Felix , Johannesson Magnus , Jonas Kai , Kindel Alexander , Kirchler Michael , Kunkels Yoram Kevin , Lindsay D. Stephen , Mangin Jan-Francois , Matzke Dora , Munafo Marcus Robert , Newell Ben R , Nosek Brian A. , Poldrack Russell , van Ravenzwaaij Don , Rieskamp Jörg , Salganik Matthew , Sarafoglou Alexandra , Schonberg Tom , Schweinsberg Martin , Shanks David , Silberzahn Raphael , Simons Daniel J. , Spellman Bobbie , Starns Jeffrey Joseph , St-Jean Samuel , Uhlmann Eric Luis , Wicherts Jelte M. , Wagenmakers Eric-Jan
Published: April 2021

We present consensus-based guidance for conducting and documenting multi-analyst studies. We discuss why broader adoption of the multi-analyst approach will strengthen the robustness of results and conclusions in empirical sciences.
An online, single-session intervention for adolescent self-injurious thoughts and behaviors: Results from a randomized trial
Authors: Dobias Mallory , Schleider Jessica L. , Jans Laura , Fox Kathryn
Published: April 2021

Background: Across 50 years of research, existing interventions for self-injurious thoughts and behaviors (SITBs) in adolescents have remained largely ineffective and inaccessible. Single-session interventions, interventions designed to last one session, may be a low-cost and timely resource for adolescents engaging in SITBs who may not otherwise receive treatment. Method: 565 adolescents (Mage = 14.95 years) endorsing recent engagement in non-suicidal self-injury (NSSI) were randomized to receive a 30-minute, web-based, single-session intervention—“Project SAVE”—or an active, attention-matched control program. Proximal outcomes were measured at baseline and immediately post-intervention. Long-term outcomes were measured at baseline and 3-month follow-up. Results: Adolescents rated Project SAVE as acceptable; 80% of participants randomized to SAVE completed the intervention. Between-group effects were non-significant for pre-registered outcomes: post-intervention likelihood of future NSSI; 3-month frequencies of NSSI and suicidal ideation at follow-up. Relative to control-group participants, SAVE participants reported short-term improvements in two exploratory outcomes: self-hatred (d = -.35, p<.001) and desire to stop future NSSI (d = .25, p = .003). Conclusions: Project SAVE is an acceptable resource for adolescents engaging in SITBs—with short-term effects on clinically-relevant outcomes. Future research may evaluate SAVE as an easy-to-access, short-term coping resource for youth engaging in SITBs.
The feasibility of patient reported outcome measures for the care of penile cancer
Authors: Branney Peter , Walters Elizabeth , Bryant Eleanor Jane , Hollyhead Cyan , Njoku Kelechi , Vyas Iona , Modica Ciara , Kayes Olly , Eardley Ian , Henry Ann
Published: April 2021

When used in routine clinical practice, Patient Reported Outcomes Measures (PROMS) can give patients tacit approval to discuss embarrassing topics, which could be particularly useful for urological nursing. The aim of this study was to assess whether it would be feasible to use two such measures for penile cancer; one for body image (the Male Genital Self-Image Scale; MGSIS-5) and another for lymphedema (the Groin and Lower Limb Lymphedema questionnaire; G3L-20). Study packs were posted to penile cancer patients who had received i) sentinel node biopsy only, ii) inguinal node dissection only, and iii) inguinal node dissection with post-operative radiotherapy with or without chemotherapy. The two measures (MGSIS-5 and G3L-20) were complemented with those specific to sexual function (IIEF) and cancer (EORTC-QLQ-C30 version 3) and a modified Lymphoedema Genitourinary Cancer Questionnaire (mLGUCQ). Twenty patients returned questionnaires. Validity and reliability analyses are presented but low participant numbers mean that results need treating with caution. Results show sufficient feasibility for the MGSIS-5 and the G3L-20 to warrant another study to attract larger numbers of participants, either over a longer time frame or at multiple sites. In these further studies, we would recommend adding 1) more Likert responses, 2) the timeframe to the MGIS and 3) exploring either the use of sexual desire psychometric measures or the addition of sexual desire items to the MGSIS for this patient group.