bluuebunny/crossref_metadata_2025 huggingface dataset:
The study of the risk of developing affective disorders in students with COVID-19
Authors: Akimova Darya D. , Osipova Natalia N. , Bardenshtein Leonid M. , Dmitrieva Elena V. , Averina Alexandra P.
Published: November 2024

BACKGROUND:
The annual increase in the number of patients with symptoms of affective pathology caused by the new coronavirus infection COVID-19 makes it necessary to study this problem.
AIMS: to study the risk of COVID-19 consequences in the form of symptoms of affective pathology in students of medical schools.
MATERIALS AND METHODS:
The study involved 131 students of medical schools: female (n=89) and male (n=42) aged 18 to 31 years, who had suffered a new coronavirus infection COVID-19 (U04.9, U07.1, U07.2), who had not previously been diagnosed with a mental disorder (headings [F00-F99] ICD-10). Clinical-psychopathological, psychometric and descriptive statistical methods were used.
RESULTS:
It was revealed that in the study group of students, in most cases, SARS-CoV-2 infection was mild (75.6%, n=99). Female and male students had the effects of COVID-19 in the form of psychopathological symptoms: manifestations of asthenia (77.9% of the studied), deterioration of cognitive functions (54.2%); affective disorders were detected in 40.4% of the studied women, much less often symptoms of mood disorder were found in men. It was also revealed that hypochondriacal experiences in the post-COVID period are much more common in women. Among all respondents, the effects of COVID-19 in the form of psychopathological symptoms manifested not only in the first weeks after the viral disease, but also persisted for up to several months (in 36.6% of respondents), without reaching the degree of affective disorder. As a result of the conducted psychometric research methods (The Spielberger State-Trait Anxiety Inventory (STAI), HCL-32 (Hypomania Checklist), the Beck Depression Inventory (BDI)), an increased level of anxiety and cyclothyme-like mood swings were revealed among female and male students.
CONCLUSIONS:
Students who had suffered from COVID-19, who did not have a previously established diagnosis of affective disorders, the most common consequences of COVID-19 (in women and men equally) were symptoms of asthenia. Cyclothyme-like mood swings with a predominance in female students were revealed. During psychometric research methods, it was revealed that situational and personal anxiety in female and male students reaches a moderate level, the tendency to depression prevails in women.
Aktivitas antioksidan dan karakteristik masker gel peel off dari ekstrak daun mangrove (Avicennia marina)
Authors: Hasibuan Nirmala Efri , Azka Aulia , Basri Basri , Mujiyanti Apri
Published: November 2024

Masker peel off merupakan salah satu produk perawatan kulit wajah yang banyak digemari karena pengaplikasiannya mudah dan tidak menimbulkan ketergantungan terhadap produk. Ekstrak daun mangrove memiliki komponen bioaktif yang memiliki aktivitas antioksidan sehingga dapat digunakan sebagai bahan baku masker peel off. Penelitian ini bertujuan untuk menentukan formula terbaik masker gel peel off dari ekstrak daun Avicennia marina berdasarkan aktivitas antioksidan. Ekstrak daun A. marina diekstraksi menggunakan metode maserasi dengan perbandingan tepung dan pelarut etanol 70% (1:5). Formulasi masker gel peel off terdiri atas 4 perlakuan penambahan ekstrak A. marina, yaitu kontrol, 0,5, 1, dan 1,5%. Parameter yang dianalisis meliputi uji fitokimia ekstrak, pH, waktu mengering, stabilitas, viskositas, aktivitas antioksidan metode DPPH, dan penilaian sensori. Ekstrak daun mangrove A. marina memiliki komponen bioaktif, yaitu senyawa flavonoid, terpenoid, steroid, tanin, dan saponin. Nilai IC50 ekstrak daun A. marina sebesar 44,88±0,90 ppm. Formulasi masker gel peel off terbaik pada konsentrasi ekstrak etanol daun A. marina 1,5% dengan nilai IC50 paling baik, yaitu 336,86±4,89 ppm. Karakteristik fisik masker gel peel off A. marina perlakuan terbaik, yaitu pH 5,5, homogen, waktu pengeringan 20,10 menit, dan nilai viskositas 175,00 mPa. Penilaian sensori masker gel peel off ekstrak daun A. marina parameter ketampakan, aroma, warna, dan tekstur netral hingga agak disukai panelis. Ekstrak daun A. marina dapat diaplikasikan pada pembuatan masker gel peel off.
In silico analysis of ethyl acetate Bruguiera gymnorhiza leaf extracts as an anti-inflammatory agent
Authors: Diana Fifi Atma Nur , Riyadi Putut Har , Susanto Eko
Published: November 2024

Bruguiera gymnorhiza is a mangrove plant that contains many bioactive compounds, which exhibit anti-inflammatoryproperties. This study aims to evaluate the anti-inflammatory potential of bioactive compounds extracted from B. gymnorhiza leaves using ethyl acetate, through in silico analysis. A literature review was conducted using internationally recognized electronic databases to identify the chemical profiles of these compounds. In silico analyses were performed using PASS Server to predict biological activity, SwissADME for drug discovery potential, and ProTox III for toxicity assessment. Molecular docking was performed using the IKKβ receptor. A literature review identified 15 compounds present in the leaves of B. gymnorhiza. PASS Server analysis revealed that all identified compounds exhibited anti-inflammatory properties. Further evaluation using SwissADME and ProTox III indicated favorable drug-likeness and absorption, distribution, metabolism, and excretion potential, with varying levels of toxicity; four compounds were classified as Class 3, five as Class 4, four as Class 5, and two as Class 6. Molecular docking results demonstrated that elemicin and lauric acid formed hydrogen bonds with IKKβ, with binding energies of -4.4 kcal/mol and -6.6 kcal/mol, respectively, suggesting significant anti-inflammatory activity. These findings provide a foundation for the development of anti-inflammatory drugs based on B. gymnorhiza leaf extracts.
Sustainable cold supply chain management of tuna agroindustry: A literature review and future research
Authors: Wibowo Raden Bagus Tri Joko , Marimin Marimin , Machfud Machfud , Anggraeni Elisa , Taryono Taryono
Published: November 2024

The tuna agro-industrial cold supply chain faces complex challenges. The implementation of cold chains has economic, social, and environmental implications. Breaking the cold chain directly reduces tuna quality. To overcome these challenges, an effective and efficient cold chain management method that focuses on the aspects of risk, performance, value chain, and sustainability is required. This study aimed to analyze the methods used in cold chain management and develop an integrated framework to increase the effectiveness and efficiency of sustainable cold supply chain management in tuna agro-industries. This study uses a systematic literature review (SLR) approach. Scientific article search databases using Scopus, Google Scholar, and others in 2013-2023. The selection resulted in 86 articles for further studies. The results of this study show that there are still very few cold chain studies in the tuna agro-industry. Cold chain studies on risk, performance, and sustainability aspects are dominated by quantitative methods with the following percentages: 76%, 58%, and 92%, respectively. By contrast, studies on the value chain aspect are dominated by descriptive qualitative methods (89%). This study found that the tuna cold chain problem in Indonesia is a soft problem on the upstream side and a hard problem on the downstream side. These two properties are rarely considered in single cold chain studies. The properties of the soft and hard systems were studied using qualitative and quantitative methods, respectively. In future research, we will develop an integrated framework for tuna agro-industry cold chain management in terms of performance, risk, value chain, and sustainability by considering the soft and hard aspects of the cold chain from onboard the ship to the consumer.
Profil asam lemak abon ikan dengan penambahan buah nangka selama penyimpanan
Authors: Sukmiwati Mery , Diharmi Andarini , Sari Noor Ira
Published: November 2024

Abon ikan merupakan produk yang terbuat dari daging ikan yang diberi bumbu sebagai penambah citarasa. Penambahan buah nangka pada abon diharapkan dapat menambah citarasa dan aroma, meningkatkan nilai gizi dan menambah variasi produk abon ikan. Penelitian ini bertujuan untuk menentukan karakteristik mutu abon ikan patin dengan penambahan nangka selama penyimpanan. Rasio antara ikan patin dan nangka adalah 2:1 (b/b). Parameter uji yang dilakukan antara lain kadar lemak, asam lemak bebas, bilangan peroksida dan asam lemak total. Penelitian menggunakan rancangan acak lengkap (RAL) dengan perlakuan lama penyimpanan berbeda, yaitu 15, 30 dan 45 hari dengan 3 kali ulangan. Lama penyimpanan berbeda menunjukkan kadar lemak 23,39-23,45%, asam lemak bebas 0,34-0,38% dan bilangan peroksida pada abon ikan nangka meningkat pada penyimpanan 45 hari dengan nilai 5,74-8,26 meq/Kg. Asam lemak total pada abon nangka selama penyimpanan mengalami peningkatan berkisar 80,58-88,48%. Kandungan asam lemak tertinggi, yaitu pada asam oleat 33,36-36,57%, sedangkan yang paling rendah, yaitu asam pentadekanoat 0,03-0,04% dan asam arakidonat 0,03-0,04%.
Algunos aspectos del uso de los demostrativos en el español Sevillano
Authors: Pinheiro Graziela Bassi , Araujo Leandro Silveira de
Published: November 2024

Esta investigación tiene como objetivo principal describir el uso de los demostrativos en la modalidad oral de la variedad del español andaluz. El interés sucede de la posibilidad de reducción del sistema ternario de los demostrativos, por lo que se pueden identificar dos principales normas en español: (i) ‘ese’ se encaja en el campo funcional de ‘aquel’, estableciendo una variable em que ‘ese’ se opone a ‘este’, (ii) ‘ese’ se neutraliza y ‘este’ se opone a ‘aquel’. De ese modo, avanzamos la investigación analizando cómo ocurre esa variación en el español hablado en Sevilla. Nos amparamos en los supuestos teórico de la Sociolingüística y analizamos los datos disponibles en el Corpus del PRESEEA (Proyecto Para el Estudio Sociolingüístico del Español de España y de América). Los resultados muestran, entre otros, una variación en el uso de ‘este’ y ‘ese’ con función anafórica y usos, tales como operadores conversacionales y valores afectivos e irónicos.
signo peirceano y su potencial para el análisis lingüístico de las lenguas señadas
Authors: Val Santiago
Published: November 2024

El término clasificador es usado ampliamente en lingüística de lenguas de señas para hablar de ciertos signos que parecen vincularse de forma no arbitraria con los objetos y procesos a los que refieren. Sin embargo, hay muy poco textos en español que describan en detalle cómo ingresa este término a la subdisciplina y lo que implica. Este artículo apunta a compensar esta carencia, presentando, además, varios de los problemas que inherentes a su uso para la descripción de las unidades y mecanismos propios de las lenguas de señas. Finalmente, en base a ejemplos concretos tomados de narraciones videograbadas en lengua de señas uruguaya, se muestra cómo, tomando como base la semiótica peirceana, se podrían resolver varios de los problemas vinculados al concepto de clasificador y a su uso en el análisis lingüístico de las lenguas de señas.
Pesquisa em rede social sob a ótica bakhtiniana do dialogismo e da responsividade
Authors: Assunção Emerson Tadeu Cotrim , Cavalcante Filho Urbano
Published: November 2024

É inegável que as relações sociais na atualidade estão afetadas pelos enunciados circulantes na Web. Isso se comprova pelo crescente número de pesquisas de objetos advindos dos tecnodiscuros (Paveau, 2021) sobre as rotinas dos cidadãos, a exemplo do impacto das redes sociais na divulgação da ciência e sobre negacionismos científicos. Pensando na potencialidade da Web e em afetamentos discursivos, objetiva-se apresentar procedimentos de coleta de dados em ambiente virtual que tratam de comentários de negação da ciência dispostos no X/Twitter da Veja (@Veja) em matérias sobre ciências da saúde no período de agravamento da pandemia no Brasil (março de 2020) e como esses comentários são dialógicos e responsivos (Bakhtin, 2015; 2016; Volóchinov, 2018) com os discursos de autoridade (Volóchinov, 2018) de Jair Bolsonaro, ex-Presidente do Brasil. A pesquisa se enquadra na abordagem qualitativa (Flick, 2009; Minayo, 2012) de inspiração netnográfica (Kozinets, 2014) e segue os procedimentos: a) utilizando a ferramenta de busca do próprio X/Twitter, buscou-se notícias com base nas palavras-chave sobre ciências da saúde (Brasil, 2022); em seguida, b) categorizou-se os comentários com negacionismos em palavras concretas; após isso, c) criou-se a nuvem de palavras com os termos de maior recorrência; feito isso d) fez-se uma criteriosa busca no google.com com esses mesmos negacionismos em discursos governamentais no Brasil e, por fim, e) analisou-se como esses comentários recuperam sentidos dos discursos de Jair Bolsonaro sobre a pandemia. As análises evidenciam que os discursos de negação da ciência presentes nos comentários estão em relação dialógico-responsiva com os discursos do ex-presidente.
Avaliação social das realizações [z, ʒ] de fricativa pós-vocálica diante de soantes coronais na comunidade de fala potiguar (RN)
Authors: Bezerra Gabriel Sales Duarte , Silveira Eliete Figueira Batista da
Published: November 2024

Este trabalho objetiva descrever o valor social das realizações [z] e [ʒ] do arquifonema fricativo diante de soantes coronais /n, l/ na fala do Rio Grande do Norte (RN). Alinhados aos pressupostos teórico-metodológicos da Sociolinguística (Weinreich; Labov; Herzog, 2006 [1968]; Labov, 2008 [1972]), organizamos amostra de dados de percepção coletados por meio de um questionário de atitudes linguísticas, elaborado de acordo com a técnica de falsos pares (Lambert et al., 1960) e hospedado na plataforma Google Forms. A amostra analisada contém respostas de 76 indivíduos a 8 escalas de atributos, distribuídos nas categorias de competência, integridade pessoal, atratividade social e associação geográfica, além de uma escala de similaridade de fala e de tarefas de atribuição de escolaridade, faixa etária, atividade profissional e naturalidade. A análise é realizada pelos métodos de regressão logística ordinal e multinomial, com uso dos pacotes ordinal (Christensen, 2019) e mclogit (Elff, 2022), executados no software R (R Core Team, 2022). Os resultados indicam que as avaliações das realizações fonéticas de fricativa variam de acordo com o segmento subsequente. Diante de /n/, contexto em que parece haver predominância de formas palatais na fala do RN, as realizações [z, ʒ] são, no geral, equilibradamente avaliadas. Em contrapartida, diante de /l/, contexto em que a palatalização parece ser ainda pouco produtiva, é indicada preferência pela realização alveolar como marca da identidade regional, embora não seja registrada estigmatização da palatal.
Pragmatic Uses of Gestures in Brazilian Portuguese in Contexts of Negation
Authors: Graça Beatriz , Avelar Maíra
Published: November 2024

Drawing on discussions about the pragmatic functions of gestures, this study demonstrates how recurrent gestures in Brazilian Portuguese convey performative and metapragmatic functions in various communicative contexts of negation. To illustrate these pragmatic uses, we selected six examples of recurrent gestures performing distinct pragmatic functions from Brazilian TV shows, TED Talks, and legislative sessions. The dataset, comprising 565 samples (N = 565), was analyzed using the Methods of Gesture Analysis (MGA) and the Linguistic Annotation System for Gestures (LASG), focusing on gesture forms, functions, and their semantic relation with speech. Statistically significant results (p < 0.001) indicate that recurrent gestures used in contexts of negation in Brazilian Portuguese operate at a pragmatic level, contributing to the utterance’s illocutionary force, and often at a metapragmatic level, where they mark stancetaking and signal the speaker’s attitude toward the interlocutor.
Peningkatan Motivasi dan Pemahaman PPKN Siswa SMP melalui Implementasi Model PBL Berbasis TGT
Authors: Arini Arlinda Dewi , Sukriono Didik
Published: November 2024

Implementasi Model PBL Berbasis TGT untuk Meningkatkan Motivasi dan Pemahaman PPKn di SMPN 8 Malang merupakan bentuk pengabdian masyarakat yang bertujuan untuk meningkatkan kualitas pembelajaran PPKn di tingkat SMP. Penelitian ini menggunakan metode kualitatif deskriptif, dengan mengombinasikan studi literatur dari penelitian terdahulu, analisis kebutuhan program, serta implementasi kegiatan inti program. Hasil penelitian menunjukkan bahwa model PBL berbasis TGT efektif dalam meningkatkan motivasi belajar dan pemahaman siswa terhadap materi PPKn. Langkah-langkah konkret dalam implementasi model ini, seperti pembukaan pembelajaran yang mengedepankan nilai religius, nasionalisme, dan disiplin, serta kegiatan inti yang melibatkan kerja kelompok, permainan, dan evaluasi pengalaman belajar, berkontribusi positif dalam menciptakan lingkungan pembelajaran yang kondusif dan dinamis. Temuan ini menegaskan pentingnya pendekatan pembelajaran yang aktif, responsif, dan kolaboratif dalam meningkatkan kualitas pendidikan.
Penerapan Model Pembelajaran Teams Games Tournament untuk Meningkatkan Keaktifan Belajar Peserta Didik Kelas 1 Sekolah Dasar
Authors: Anjarwati Rika , Dewi Radeni Sukma Indra
Published: November 2024

Model pembelajaran kooperatif adalah salah satu strategi pengajaran yang sejalan dengan fitrah manusia sebagai makhluk sosial yang saling bergantung satu sama lain. Model ini menekankan tujuan dan tanggung jawab bersama, pembagian tugas, serta rasa senasib. Dalam konteks pembelajaran kooperatif, peserta didik dilatih untuk saling berbagi (sharing) pengetahuan, pengalaman, tugas, dan tanggung jawab. Proses saling membantu serta berlatih berinteraksi, berkomunikasi, dan bersosialisasi menciptakan lingkungan belajar yang mencerminkan miniatur kehidupan bermasyarakat. Hal ini memungkinkan peserta didik untuk belajar menyadari kekurangan dan kelebihan masing-masing. Penelitian ini menggunakan metode Penelitian Tindakan Kelas (PTK) dengan pendekatan deskriptif kualitatif, bertujuan untuk meningkatkan keaktifan belajar peserta didik melalui model pembelajaran kooperatif Teams Games Tournament (TGT). Penelitian ini disusun dalam format siklus yang mengacu pada model spiral yang dikembangkan oleh Kemmis dan McTaggart. Model pembelajaran TGT ini tidak hanya mendorong peserta didik untuk terlibat dalam kegiatan fisik, seperti mengamati, menulis, dan membaca, tetapi juga melibatkan kegiatan mental, seperti memecahkan masalah, menganalisis, dan mengambil keputusan. Dengan demikian, penerapan model pembelajaran ini terbukti efektif dalam meningkatkan aktivitas dan keaktifan peserta didik di Sekolah Dasar, yang ditunjukkan oleh peningkatan pada setiap indikator keaktifan peserta didik di siklus I dan II.
Efektivitas Model Project-Based Learning dalam Implementasi TaRL pada Pembelajaran Berdiferensiasi Siswa Kelas VII
Authors: Dewantari Arrin Suci , Nuris Dudung Ma’ruf
Published: November 2024

Pembelajaran Abad-21 berupaya membentuk peserta didik yang memiliki kemampuan berkomunikasi efektif, kreatif, dan mampu bersaing dalam era digital sehingga menjadi individu yang berketerampilan dan adaptif. Penelitian ini bertujuan untuk mengetahui dampak positif yang muncul dari peserta didik selama proses implementasi pembelajaran berdiferensiasi dengan pendekatan Teaching at the Right Level (TaRL), khususnya melalui model pembelajaran berbasis proyek. Metode penelitian yang digunakan adalah kualitatif dengan pendekatan deskriptif. Subjek penelitian terdiri dari peserta didik kelas VII-A SMP Negeri 2 Pakis tahun pelajaran 2023/2024. Hasil observasi menunjukkan bahwa kegiatan pembelajaran di kelas menjadi lebih aktif dan terjadi peningkatan kreativitas peserta didik. Selain itu, terdapat peningkatan motivasi belajar dan rasa tanggung jawab peserta didik dalam menyelesaikan tugas kelompok. Berdasarkan hasil penelitian yang telah dipaparkan, dapat disimpulkan bahwa implementasi pembelajaran berdiferensiasi dengan pendekatan Teaching at the Right Level (TaRL) melalui model Project-Based Learning (PjBL) memberikan banyak dampak positif dalam kegiatan pembelajaran, khususnya bagi peserta didik. Dengan munculnya dampak positif ini, diharapkan akan sejalan dengan peningkatan hasil belajar peserta didik.
Implementasi Pembelajaran IPS Berbasis Permainan Tradisional Boi-Boian
Authors: Yusman Salsabila Farodis , Rosyida Fatiya
Published: November 2024

Pembelajaran konvensional masih banyak dilakukan oleh guru yang membuat tidak adanya ruang bagi peserta didik mengaplikasikan pengetahuan yang dimilikinya. Tujuan penelitian ini adalah untuk mengetahui bagaimana implementasi pembelajaran IPS berbasis permainan tradisional Boi-Boian di SMPN 9 Malang. Penelitian yang digunakan kualitatif dengan metode PTK yang mengumpulkan datanya menggunakan observasi dan dokumentasi. Prosedur tindakan kegiatan direncanakan 2 siklus, dengan tiap siklus terdapat 4 tahap: perencanaan, pelaksanaan, pengamatan dan refleksi. Dalam penelitian peneliti menemukan 4 langkah dalam mengimplementasikan permainan Boi-Boian, yaitu proses perencanaan, persiapan, pelaksanaan, dan evaluasi. Analisis evaluasi implementasi permainan tradisional Boi-Boian pada mata pelajaran IPS di SMPN 9 Malang kelas VIII D menggunakan teknik analisis SWOT. Dari tabel skor pada sikulus I dan siklus II dapat dilihat terdapat peningkatan skor yang diperoleh oleh setiap kelompok. Selama proses pelaksanaan permainan tradisional Boi-Boian peserta didik secara aktif dalam kegiatan kelompok, dengan melakukan berbagai strategi seperti seperti melakukan pembagian tugas dalam kelompok. Peserta didik dalam kelompok saling bekerja sama agar dapat menjawab pertanyaan dengan benar dan setiap kelompok terlihat antusias dan kompetitif dalam memengkan permaianan.
Peningkatan Pemahaman Kognitif Siswa pada Materi Tari Tradisional melalui Model Learning Start with A Question di Kelas VIII SMP
Authors: Anggara Widi Dwijati , Rahayuningtyas Wida
Published: November 2024

Pada pembelajaran seni budaya sub bidang tari pada materi keunikan tari tradisional di kelas VIII E SMPN 1 Kasembon siswa mengalami kendala yang menyebabkan ketidaktuntasan nilai hasil belajar pada ranah kognitif. Kendala yang dihadapi adalah kurangnya antusias dan berkonsentrasi dalam proses pembelajaran. Model pembelajaran yang diterapkan sebelumnya juga kurang memacu keaktifan siswa untuk terlibat aktif dalam pembelajaran. Tujuan penelitian ini adalah mendeskripsikan penerapan model pembelajaran learning start a with question dalam upaya peningkatan hasil belajar siswa pada aspek kognitif materi keunikan tari tradisional. Metode yang digunakan pada penelitian ini adalah peneltitian tindakan kelas yang dilaksanakan dalam dua siklus yakni siklus 1 dan siklus 2. Setiap siklus mencakup empat tahap yakni perencanaan, tindakan, pengamatan dan refleksi. Pembelajaaran diawali dengan sebuah pertanyaan yang diberikan oleh guru sebagai awal pembelajaran. Siswa diminta untuk mengajukan jawaban berdasarkan pengetahuan dan pengalaman belajar sebelumnya. Siswa dituntut mengajukan pertanyaan mengenai materi yang belum dipahami pada pembelajaran sebelumnya. Hasil penelitian ini membuktikan bahwa penerapan model pembelajaran LSQ mampu meningkatkan hasil belajar dan keaktifan siswa dalam pembelajaaran. Sebelum diadakan penelitian ketuntasan hasil belajar mencapai 34 persen kemudian meningkat 53 persen pada siklus 1 dan meningkat 84 persen pada siklus 2. Sehingga penerapan model pembelajaran LSQ berhasil meningkatkan hasil belajar siswa pada aspek kognitif, yakni siswa berpikir kristis, terampil menyusun pertanyaan dan jawaban, serta aktif dalam proses pembelajaran.
Pengaruh Budaya Sekolah terhadap Pembentukan Karakter Siswa Sekolah Dasar
Authors: Indriani Dwi Fitria , Anggraini Nur Afni , Hasanah Wahyu Ezy Asmi , Bintartik Lilik , Lestari Ana Dwi
Published: November 2024

Pendidikan karakter penting untuk ditanamkan sejak dini, khususnya di sekolah dasar, sebagai fondasi bagi generasi penerus dalam menghadapi tantangan era globalisasi dan perkembangan teknologi yang pesat. Tantangan-tantangan ini berpotensi memengaruhi karakter anak bangsa, sehingga diperlukan upaya untuk menanamkan nilai-nilai luhur yang sejalan dengan karakteristik dan budaya bangsa Indonesia. Penelitian ini bertujuan untuk mengeksplorasi dan mendeskripsikan bentuk-bentuk karakter yang dimiliki oleh siswa di SDN Percobaan 1 Malang, yang terbentuk melalui penerapan budaya sekolah. Menggunakan pendekatan kualitatif naratif, penelitian ini mengandalkan teknik wawancara mendalam, observasi langsung, serta dokumentasi foto sebagai metode pengumpulan data. Subjek penelitian ini adalah siswa kelas 5A di SDN Percobaan 1 Malang. Hasil penelitian menunjukkan bahwa budaya sekolah yang diterapkan, seperti rutinitas membaca asmaul husna, berdoa bersama, menyanyikan lagu-lagu nasional, hormat bendera, dan memberi salam kepada guru, secara efektif membangun karakter positif siswa. Budaya ini selaras dengan profil Pelajar Pancasila, yang mencerminkan nilai-nilai moral dan nasionalisme dalam diri siswa.
Manfaat dan Tantangan Penggunaan Artificial Intelligence (AI) bagi Guru dan Peserta Didik di Era Society 5.0
Authors: Pratiwi Rachel Theresa Laras , Yunus Mahmuddin
Published: November 2024

Teknologi dan industri di abad ke-21 mengalami perkembangan pesat, khususnya dengan hadirnya era Society 5.0, yaitu era yang tidak hanya berfokus pada kecanggihan teknologi, tetapi juga pada kemanusiaan dan kesejahteraan sosial. Di era ini, teknologi seperti kecerdasan buatan (Artificial Intelligence atau AI), Internet of Things (IoT), dan big data berperan besar dalam mendukung upaya meningkatkan kualitas hidup manusia dan membantu menyelesaikan masalah-masalah sosial yang kompleks. Society 5.0 dengan demikian merupakan perpaduan antara kemajuan teknologi dan nilai-nilai kemanusiaan, dimana teknologi dimanfaatkan secara lebih bijaksana untuk kebermanfaatan yang lebih luas. Transformasi ini juga memengaruhi dunia pendidikan, terutama melalui integrasi AI dalam proses pembelajaran. Penggunaan AI di bidang pendidikan menawarkan banyak manfaat bagi guru dan peserta didik, seperti pembelajaran yang lebih personal dan efisien. Namun, di sisi lain, hal ini juga membawa tantangan. Guru diharapkan untuk terus mengembangkan keterampilan digital agar peran mereka sebagai pengajar dan pembimbing tidak tergantikan oleh teknologi. Bagi peserta didik, keberadaan AI memerlukan pendampingan yang kuat dari guru dan orang tua agar mereka tetap bertanggung jawab dan tidak bergantung sepenuhnya pada teknologi, sehingga kemampuan berpikir kritis dan belajar mandiri mereka tetap terjaga. Dengan panduan yang tepat, AI dapat menjadi alat yang efektif dalam memperkaya pengalaman belajar peserta didik dan meningkatkan kualitas pendidikan.
OPTIMIZATION OF COOPERATION BETWEEN NEUROLOGISTS AND GENERAL PRACTITIONERS: IMPROVING THE QUALITY OF CARE AND TREATMENT OUTCOMES FOR PATIENTS WITH CANCER
Authors: E.S. Putilova , L.M. Mavliutova , A.A. Tulba , Ch.R. Khi , N.A. Kolesova
Published: November 2024

Many cancer patients undergoing chemotherapy experience neurological side effects, including neuropathy and cognitive changes that significantly affect their daily lives. Functional medicine offers an integrative approach to solving these problems, focusing on the individual needs of each patient. It aims to identify and treat the underlying causes of neurological problems after chemotherapy through a comprehensive analysis of the patient’s lifestyle, environmental influences and genetic factors. This approach not only alleviates symptoms, but also contributes to improving the overall health and well-being of patients. An important place in the integrative approach is occupied by an integrated approach to treatment, which is carried out by neurologists together with doctors of other practices, including general practice. Such a campaign allows you to study the patient’s condition at a high level and more accurately determine the risks to his health, as well as select the necessary treatment methods. By exploring the role of functional medicine in providing neurological care after chemotherapy, we will see how it offers personalized care plans designed to improve the recovery process.
THE IMPACT OF CARDIAC REHABILITATION ON QUALITY OF LIFE AND 6 MINUTE WALK TEST IN POST GLENN PATIENTS
Authors: A.K.A. Araquib , A.O.A. Abdelhady , Missiri A.M.A.B. El , Y.M.M. Fahmy
Published: November 2024

Background: Patients with congenital heart disease (CHD), particularly those with single ventricular physiology undergoing Glenn shunt, often experience limited functional capacity and decreased quality of life (QoL). This study evaluates the impact of a 12-week cardiac rehabilitation (CR) program on functional capacity, measured by the 6-minute walk test (6MWT), and QoL in post-Glenn (PG) patients. Methods: This randomized controlled trial included 35 PG patients aged 6 years and above, randomized into two groups: the CR group (n=15) participated in a 12-week CR program, while the control group (n=20) received standard care. Pre- and post-rehabilitation assessments included echocardiography, the 6MWT, and QoL evaluation using the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Results: After 3 months, the CR group showed significant improvements in 6MWT distance, increasing from 378.67 ± 53.97 m to 411.00 ± 61.01 m (p < 0.001), compared to a non-significant change in the control group. Heart rate (HR) decreased in the CR group (pre: 92.27 ± 8.02 bpm, post: 84.93 ± 8.48 bpm, p < 0.05). QoL scores improved in the CR group, with a median MLHFQ score decrease from 19 (IQR 18-24) to 16 (IQR 12-21) (p < 0.05). No significant changes in echocardiographic parameters were observed in either group. Conclusion: A 12-week CR program significantly improves functional capacity and QoL in PG patients. These findings support the implementation of CR programs in this population to enhance physical activity and overall well-being.
TRANSCRIPTOME OF METASTATIC COLORECTAL CANCER
Authors: T.A. Dronova , N.N. Babyshkina , D.N. Kostromitsky , D.A. Eremin , N.V. Cherdyntseva
Published: November 2024

Colorectal cancer has been one of the leading malignant neoplasms in males and females over many years. The vast majority of patients (70%) with colon lesions develop distant metastases to the liver, which are the main cause of death.
Peculiarities of the course of non-small cell lung cancer and the percentage / of lymphocytes in blood of patients considering gender specific difference, upon COVID-19 before the beginning of antitumor treatment
Authors: G.V. Zhukova , E.M. Frantsiyants , D.A. Kharagezov , A.I. Shikhlyarova , I.V. Kaplieva , E.A. Mirzoyan , A.G. Milakin , M.S. Zinkovich
Published: November 2024

The issue of the peculiarities of the course of the malignant process and the informative value of hematological parameters in patients with non-small cell lung cancer (LC) considering gender specific difference, upon COVID-19 before the beginning of antitumor treatment, has been poorly studied.
METHODOLOGICAL APPROACHES TO STANDARDIZATION OF COMPLEX PHYTOADAPTOGENS FOR PREVENTIVE ONCOLOGY
Authors: O.A. Bocharova , I.V. Kazeev , V.G. Shevchenko , O.P. Sheychenko , R.V. Karpova , E.V. Bocharov , A.A. Aksenov , M.V. Utkina , V.G. Kucheryanu , N.V. Pyatigorskaya , V.S. Kosorukov , I.S. Stilidi
Published: November 2024

Preventive oncology can solve such problems as preventing the appearance of tumors, relapses after primary treatment, and complications after chemo-radiation therapy. The prospects for use of phytoadaptogens (Panax ginseng, Rhodiola Rosea, Eleutherococcus senticosus etc.), which pleiotropically influence the body along the homeostasis axis (neuro-endocrine-immune systems), are obvious.
Plasmonic photothermal photodynamic therapy in mice with colorectal cancer
Authors: A.B. Bucharskaya , N.A. Navolokin , G.N. Maslyakova , N.A. Shushunova , M.L. Chekhonatskaya , N.G. Khlebtsov , B.N. Khlebtsov , O.I. Guslyakova , V.D. Genin , E.A. Genina , V.V. Tuchin
Published: November 2024

The need for searching for new methods of antitumor therapy is due to the sharp increase in morbidity and mortality from cancer, as well as because of the fact that conventional chemo- and radiotherapy are often insufficiently effective owing to the development of tumor cells resistance. Plasmonic photothermal therapy (PPT) is a method based on tumor hyperthermia by laser heating of metal nanoparticles with plasmon resonance properties.
METABOLIC EFFECTS OF ACCOMPANYING ACTIVATION THERAPY IN ONCOPATHOLOGY
Authors: A.I. Shikhlyarova , E.M. Frantsiyants , G.V. Zhukova , I.V. Kapliyeva , I.V. Neskubina , V.A. Bandovkina
Published: November 2024

At present, there is a primacy of molecular and genetic concepts on the mechanism of the appearance and development of cancer. Much less attention is paid to an attention and an understanding of the metabolic features of malignant cells as a result of transformation at the genetic level.
Prospects for complex mitochondrial therapy in oncology
Authors: A.F. Prokopov
Published: November 2024

The aim of the study: Brief overview of the background, current status and possibilities of mitochondrial therapy of malignant tumors.
Domestic injectable calcium phosphate bone cements for onco-orthopedics: development and biological evaluation
Authors: I.K. Sviridova , M.A. Goldberg , V.A. Kirsanova , S.A. Akhmedova , P.A. Krokhicheva , D.R. Khairutdinova , N.S. Sergeeva , V.S. Komlev
Published: November 2024

The creation of injectable bone cements (BC) remains a pressing issue in modern biomaterial science due to the prospects for their use in minimally invasive surgical interventions in onco-orthopedics for replacing bone defects in patients that occur after removal of primary or metastatic spinal tumors.
Avaliação dos efeitos e impactos das inundações no Rio Grande do Sul
Authors: Suarez Ginés , Bello Omar , Campbell Jack
Published: November 2024

O Estado do Rio Grande do Sul, localizado no sul do Brasil, experimentou um evento extraordinário de chuvas e inundações entre o final de abril e maio de 2024. Essa região, caracterizada por sua vulnerabilidade a diversos perigos ambientais, foi afetada por um sistema de baixa pressão que trouxe chuvas intensas e persistentes. O evento se alinhou com a temporalidade histórica regional, que prevê os maiores volumes de precipitação durante o outono.
As precipitações excederam significativamente as médias históricas, com algumas áreas registrando até 300 mm de chuva em um único dia. Isso resultou na saturação do solo e no transbordamento de rios e córregos, causando inundações generalizadas tanto em áreas urbanas como rurais. Entre os principais rios afetados estão o Jacuí, Taquari, Caí e Guaíba, que atingiram níveis críticos e causaram inundações severas nas comunidades ribeirinhas.
O governo estadual, em coordenação com as autoridades municipais e federais, respondeu declarando estado de calamidade pública em 95 municípios e estado de emergência em outros 323.

O desastre teve um impacto devastador na vida de milhares de pessoas, comprometendo seriamente a segurança, saúde e bem-estar da população afetada. A perda de infraestrutura essencial dificultou ainda mais os esforços de socorro e recuperação. De acordo com os boletins emitidos periodicamente pela Defesa Civil do Rio Grande do Sul, a população potencialmente afetada chega a 2.398.255 pessoas. O Laboratório de Inovação do IBGE, a partir de um cruzamento entre a mancha de inundação e a geolocalização da população de acordo com o Censo Demográfico 2022, contabiliza 876.565 pessoas diretamente afetadas.

Quanto à população afetada primária, registraram-se 183 óbitos (115 homens, 60 mulheres e 7 não identificados, dos quais pelo menos 55 são pessoas idosas e 13 crianças ou adolescentes), 27 desaparecidos e 806 feridos. O número de resgates realizados pelas autoridades públicas foi de 77.712, sendo que 581.638 pessoas ficaram desalojadas. Estabeleceram-se 980 abrigos em 117 municípios, geridos por autoridades públicas, pela sociedade civil organizada ou voluntários. Neles, foram atendidas 81.170 pessoas impedidas de retornar a suas casas, temporária ou permanentemente, e que não tinham alternativa de moradia.

As inundações do Rio Grande do Sul foram um evento catastrófico, provavelmente um dos mais caros da história do estado. O impacto global estimado é de aproximadamente R$ 88,9 bilhões. Dada a magnitude do desastre, a resposta envolveu a coordenação dos governos federal, estadual e municipal. Esta colaboração deve ser ainda mais profunda e sinérgica durante a reconstrução e na preparação e redução de riscos para eventos futuros, o que permitirá que as comunidades gaúchas se tornem mais resilientes.
Seeds to Inclusion: What We Know and Don't Know About Disability Policy
Authors: Duryea Suzanne , Martínez Claudia , Pereira María Antonella
Published: November 2024

Approximately one in seven people in Latin America and the Caribbean live with a disability, yet barriers and needs are often overlooked, and policies intended to foster inclusion remain understudied. This report examines the effectiveness of disability inclusion policies across education, health, labor markets, and social protection. A closer look at the realities for people with disabilities in the region reveals a much more nuanced picture of the magnitude of gaps, quality of services, and distinct challenges compared to those without disabilities. By highlighting evidence-based interventions, this volume seeks to encourage policy approaches that foster inclusion and improve the quality of life of millions living with disabilities.
Comparative analysis of purse-string method versus conventional methods for stoma closure
Authors: Hüseynov Amil , Vural Veli
Published: November 2024

Objectives: Stoma surgery, essential for treating conditions like Crohn's disease, colorectal cancer, and diverticular disease, requires effective closure techniques to minimize postoperative complications and enhance patient outcomes. This study aims to compare the purse-string technique with traditional closure methods, emphasizing postoperative outcomes and complications.
Methods: This study retrospectively reviewed the medical records of 44 patients who underwent stoma closure at Antalya University Hospital between August 2015 and November 2019. Twenty-one patients underwent the purse-string (PS) method and twenty-three underwent conventional methods (CM). Patient demographics, such as age, sex, body mass index, and medical history, were recorded. Variables such as surgical duration, complication rates, and recovery periods were meticulously analyzed.
Results: The analysis indicated that patients treated with the PS method had notably reduced infection rates (9.5% in PS vs. 21.5% in CM) and quicker healing times compared to conventional methods. The circular suture pattern of the PS method demonstrated greater efficacy in minimizing postoperative complications. Complications were observed in 21.5% of patients with CM and 9.5% of patients with the PS method. Notably, systematic reviews have shown that the PS closure technique reduces surgical site infection (SSI) rates, although its impact on the length of hospital stay remains uncertain.
Conclusions: The PS method shows a significant advantage over traditional techniques in stoma closure. Its benefits in lowering infection rates and promoting quicker recovery emphasize its potential as a preferred method in surgical practice. The study advocates for the broader adoption of the PS method in clinical settings, given its positive impact on patient outcomes.
Cities and Their People: Dwelling in the Anthropic Time of N. K. Jemisin’s New York
Authors: Sugiera Małgorzata
Published: November 2024

The article starts with Martin Heidegger’s 1951 essay “Bauen Wohnen Denken,” recently rethought by Jeff Malpas in his book Rethinking Dwelling from today’s perspective of urban and metropolitan dwelling. However, while defining dwelling relationally, the Australian philosopher still thinks about the human as a being-in-place in a traditional, human-centred way. Thus he overlooks how tightly humans are entangled with more-than-humans: with biological, geological, and technological entities and agencies. For this reason, the article tackles a further rethinking of dwelling beyond human sociality, or even queering it beyond binary thinking to better depict what it proposes to call urban subjectivity. Reading N. K. Jemisin’s recent novel duology The Great Cities, the article argues that urban subjectivity is a distributed phenomenon, which both incorporates and elaborates on more-than-human elements. In so doing, urban subjects share a sociality not only with the animal and geological but also with technological forces and their territorial exorganic functions as an agency of anti-entropic locality (Bernard Stiegler’s “anthropic life”). Thus, creatively approached technology as a pharmakonian form of organogenesis and Derridian différance may help us keep the entropic and neganthropic forces in balance, as pertinently demonstrated in Jemisin’s duology.
Voices of the Dead: Robert Eggers’s The Lighthouse and the Horror Genre
Authors: Morawiec Maciej
Published: November 2024

This article examines the 2019 film The Lighthouse, directed by Robert Eggers, which follows the descent into madness of two 19th-century lighthouse keepers as they become stranded on a desolate New England island and confronted with threats both natural and supernatural. The focus of the article is primarily on the film’s employment of the cinematic language associated with the horror genre, discussed primarily in reference to the theoretical framework proposed by Noël Carroll, and thus it serves as the argument for The Lighthouse’s inclusion into the genre. I place particular emphasis on the considerations of human nature present in the film. The Lighthouse illustrates the disastrous impact of finding oneself outside of the boundaries of civilization; without the constraints imposed by society, but also without the sense of security it offers, the evil that can be found in every human being is revealed and the characters turn against each other.
Investigation of the Antimicrobial Activities of Schiff Bases Containing Triazoles
Authors: Memiş Hande , Direkel Şahin , Ünver Yasemin , Uzunoğlu Emel , Karaman Ülkü , Akdemir Cihangir
Published: November 2024

Objective: Pathogen parasites and bacteria are microorganisms that have existed throughout human history and cause different diseases. Various antimicrobial agents have become one of the treatment options in the fight against these diseases. With the increase in the number of resistant microorganisms, existing agents became ineffective and there was a need to synthesize or produce new antibiotics, antiparasitic, antiviral and antifungal drugs. There are many studies showing that Schiff base derivatives have antimicrobial properties and proving the existence of their biological activities. In this study, it was aimed to determine the antimicrobial activity of two originally synthesized compounds, a triazole-containing Schiff base, against 16 different bacterial isolates and one different Leishmania species.
Methods: In our study, the biological activities of two different newly synthesized triazole-containing Schiff base derivatives against selected one Leishmania and 16 bacteria species were evaluated by the microdilution broth (alamar blue added) method. In the study, the in vitro antibacterial activities of the compounds were determined by measuring their Minimum Inhibitory Concentration (MIC) values.
Results: Leishmanicidal activity of Leishmania infantum parasite was determined by measuring its Leishmanicidal Concentration. The compounds were found to have antimicrobial activity against bacteria and parasite at different concentrations.
Conclusion: It was concluded that the in vitro antimicrobial activity results obtained in our study will be of significant benefit to future research due to the resistance detected against drugs used in the treatment of infectious diseases and health problems arising due to the side effects of the drugs. If in vivo animal experiments and toxicity studies are as expected; We believe that the in vitro antimicrobial activity results obtained in our study will make a significant contribution to future research due to the resistance detected against drugs used in the treatment of infectious diseases and the health problems caused by their side effects.
PENERAPAN SERVICE LEARNING DENGAN METODE HYBRID UNTUK MENGEMBANGKAN MOTIVASI KEGIATAN PEMBELAJARAN
Authors: Bukidz Danny Philipe
Published: November 2024

Kegiatan Service Learning merupakan aktifitas pelayanan kepada komunitas untuk memberikan solusi atas persoalan komunitas yang ada. Aktifitas service learning selama ini dilakukan secara langsung atau luring (luar jaringan). Pada masa pandemik metode penerapan service learning sangat sulit dilakukan oleh karena pelaksanaan protokol Kesehatan. Kegiatan service learning yang dilakukan oleh UPH Kampus Medan yaitu dengan metode hybrid. Aktifitas Service learning yang dilakukan memberikan dampak lebih luas bagi pelayanan Pendidikan anak baik di Panti asuhan maupun komunitas. Tulisan ini menggunakan metode deskriptif analisis dengan metode naratif kualitatif. Hasil Penelitian dan pengabdian masyarakat ini adalah memberikan suatu kajian deskriptif  pelaksanaan service learning terhadap siswa baik di panti asuhan dan komunitas pada masa pandemik. Selain itu artikel ini memberikan evaluasi perihal efektifitas service learning dalam masa pasca pandemik.
Pelatihan kreasi minuman kopi bagi masyarakat desa Lengkong Kulon
Authors: Situmorang Ringkar , Alexandra Yoanita , Choirisa Septi Fahmi
Published: November 2024

Lengkong Kulon Village is one of the villages that have the potential to become a leading tourist village in the province of Banten. The town is located in the Pagedangan sub-district. Community Service is carried out to help village communities cultivate ten empty kiosks to sell products in the culinary business. This activity was proposed by BUMDES (Village Owned Enterprise) of Lengkong Kulon Village. The training focused on basic teaching methods regarding coffee, basic manual brewing techniques, and the famous creation of coffee menus. The training is to broaden the knowledge of the local community regarding the potential coffee business in the area. The 20 participants of this training come from the youth group of Lengkong Kulon. The training is carried out at the Multimedia Nusantara University (UMN) Campus. Activities implemented in several stages include preparation for service, implementation of service, data collection; the result of seminars; and writing the report. The results of this activity received lively enthusiasm from the local village communityabstract in bahasaDesa Lengkong Kulon adalah salah satu desa yang mempunyai potensi menjadi desa unggulan wisata di provinsi Banten. Desa yang berada di kecamatan Pagedangan. Pengabdian Kepada Masyarakat dilaksanakan untuk membantu masyarakat desa membudidayakan 10 gerobak kosong untuk keperluan penjualan produk di bidang kuliner, sesuai dengan permintaan dari BUMDES (Badan Usaha Milik Desa) Desa Lengkong Kulon. Pelatihan difokuskan pada cara pengajaran dasar mengenai kopi, teknik dasar manual brewing coffee, dan juga kreasi menu kopi, yang diharapkan akan memperluas wawasan masyarakat Desa Lengkong Kulon akan potensi bisnis kopi, serta cara pembuatannya.  20 peserta pelatihan ini datang dari kelompok pemuda karang taruna desa Lengkong Kulon. Pengabdian dilaksanakan secara off-line di Kampus Universitas Multimedia Nusantara (UMN). Kegiatan dilakukan pada beberapa tahap meliputi (1) persiapan pengabdian; (2) pelaksanaan pengabdian; (3) pengumpulan data; (4) seminar hasil pengabdian; dan (5) penulisan laporan pengabdian. Hasil dari aktivitas ini mendapatkan antusiasme yang meriah dari masyarakat desa setempat.