bluuebunny/crossref_metadata_2025 huggingface dataset:
An Alternative to Process Integration: Clarification and First Step of Monoclonal Antibodies Purification Using Flocculation, Adsorption and Filtration
Authors:   Federal University of Rio de Janeiro (UFRJ), Chemical Engineering Program, COPPE, Brazil, RJ Carvalho
Published: May 2021

Background: New strategies for up and downstream integration process are being required for end-to-end continuous process for recombinant protein. Single-use materials as well as low cost and easy processing are very welcome for this development. Monoclonal antibodies are largely produced in biopharmaceutical industry what makes it a good protein model to be used in this process. Objective: A new strategy for integrating up and downstream processes for monoclonal antibodies was developed as a three-step process: flocculation of the cell culture harvest (batch mode); followed by anion-exchange chromatography for impurities adsorption in a slurry, and single-pass tangential flow filtration (both semi-continuous mode). Methodology: To develop this integrated process, separated studies of flocculation and adsorptions conditions with anion-exchange beads were performed. After defining the optimal conditions, flocculation was performed, and the supernatant was pumped in a vessel along with beads suspension for adsorption. The adsorption was carried out in a residence time determined in the previous studies. Then, the suspension with supernatant was filtered where the antibodies were recovered in the permeate. Results: Under the adsorption conditions applied (pH 6.5 and 250 mM NaCl), the purer antibodies were recovered in the permeate, whereas the beads with adsorbed impurities remained in the retentate. Steady state profile was obtained during adsorption and filtration for all conditions studied, where no loss of product was obtained. Differently, when the overall process was considered, global yields varied between 61% and 90% due to the void volumes of the runs. Additionally, higher concentration of beads (sample/beads ratio of 41) enabled high amount of impurities removal: 98.9% of DNA and approximately 70% of host cell proteins. Regarding the retention devices studied, depth filter yielded lower void volumes when compared to lamella settler (higher than 5-fold), begetting a global antibodies recovery of 90.4% in 20% higher productivity. Conclusion: Combining both clarification and impurities removal protocols into a single one proved to be a simple, efficient and fast alternative, which improvement could be obtained by its fully automatization.
Exploring and Mapping Chemical Space with Molecular Assembly Trees
Authors: Liu Yu , Mathis Cole , Marshall stuart , Bajczyk Michał Dariusz , Wilbraham Liam , Cronin Leroy
Published: May 2021

The mathematical search of chemical space can generate an almost infinite number of molecules and it is hard to know which molecules are relevant experimentally. A way to explore the chemical space of known molecules as a function of their relative complexity might help us understand biological processes and find new relationships. Assembly theory provides an approach to explore and compare the intrinsic complexity of molecules by the minimum number of steps needed to build up the target graphs. Here we show assembly theory can be applied to networks of molecules to explore the assembly properties of common motifs and use these to define a tree of assembly spaces. This theory allows us to explore the accessible molecules connected to the tree, rather than the entire space of possible molecules. We apply this approach to prebiotic chemistry, to gene sequences, a family of plasticizers, as well as the well-known opiate class of natural products. This analysis allows us to quantify the amount of external information needed to assemble the tree and identify and predict new components in this family of molecules. Finally, by developing a new reassembly system that uses the disassembly motifs, we found that in the case of the opiates a new set of opiate-like drug candidates could be generated that would not be accessible via conventional fragment-based drug design, thereby demonstrating how this approach might find application in drug discovery.
Analytic Gradients for Restricted Active Space Second-order Perturbation Theory (RASPT2)
Authors: Nishimoto Yoshio
Published: May 2021

The computational cost of analytic derivatives in multireference perturbation theory is strongly affected by the size of the active space employed in the reference self-consistent field calculation. To overcome previous limits on active space size, the analytic gradients of single-state restricted active space second-order perturbation theory (RASPT2) and its complete active space variant (CASPT2) have been developed and implemented in a local version of OpenMolcas. Similar to previous implementations of CASPT2, the RASPT2 implementation employs the Lagrangian or Z-vector method.

The numerical results show that restricted active spaces with up to 20 electrons in 20 orbitals can now be employed for geometry optimizations.
How to Extract Adsorption Energies, Adsorbate-adsorbate Interaction Parameters, and Saturation Coverages from Temperature Programmed Desorption Experiments
Authors: Vijay Sudarshan , Kristoffersen Henrik Høgh , Katayama Yu , Shao-Horn Yang , Chorkendorff Ib , Seger Brian , Chan Karen
Published: May 2021

We present a simple scheme to extract the adsorption energy, adsorbate interaction parameter and the saturation coverage from temperature programmed desorption (TPD) experiments. We propose that the coverage dependent adsorption energy can be fit using a functional form including the configurational entropy and linear adsorbate-adsorbate interaction terms. As one example of this scheme, we analyze TPD spectra of desorption on Au(211) and Au(310) surfaces. We determine that under atmospheric pressure, the steps of both facets adsorb between 0.4-0.9 ML coverage of CO*. We show this result to be consistent with density functional theory calculations of adsorption energies with the BEEF-vdW functional.
Incorporation of [Cp*Rh] and [Cp*Ir] Species into Heterobimetallic Complexes via Protonolysis Reactivity and Dioximato Chelation
Authors: Kumar Amit , King Daniel , Day Victor W. , Blakemore James
Published: May 2021

Synthesis of multimetallic compounds can enable placement of two or more metals in close proximity, but efforts in this area are often hindered by reagent incompatibilities and lack of selectivity. Here, we show that organometallic half-sandwich [Cp*M] (M = Rh, Ir) fragments (where Cp* is η5-pentamethylcyclopentadienyl) can be cleanly installed into metallomacrocyclic structures based on the workhorse diimine-monooxime-monooximato ligand system. Six new heterobimetallic compounds have been prepared to explore this synthetic chemistry, which relies on in situ protonolysis reactivity with precursor Ni(II) or Co(III) monometallic complexes in the presence of suitable [Cp*M] species. Solid-state X-ray diffraction studies confirm installation of the [Cp*M] fragments into the metallomacrocyles via effective chelation of the Rh(III) and Ir(III) centers by the nascent dioximato site. Contrasting with square-planar Ni(II) centers, the Co(III) centers prefer octahedral geometry in the heterobimetallic compounds, promoting bridging ligation of acetate across the two metals. Spectroscopic and electrochemical studies reveal subtle influences of the metals on each other’s properties, consistent with the moderate M′•••M distances of ca. 3.6–3.7 Å in the modular compounds. The [Co,Rh] complex was found to catalyze hydrogenation of p-trifluoromethylbenzaldehyde to p-trifluoromethylbenzyl alcohol more cleanly than a 1:1 mixture of the individual monometallic precursor complexes, suggesting that this family of heterobimetallic complexes could be useful in future studies of multimetallic chemistry, especially in light of the starring role of other [Cp*M] complexes in diverse catalytic systems.
New Caledonian Crows and Hidden Causal Agents Revisited
Authors: O’Neill Laurie , Linder Garp , van Buuren Magdalena , von Bayern Auguste M. P.
Published: May 2021

A previous experiment suggested that New Caledonian crows (Corvus moneduloides; henceforth NCCs) can reason about hidden causal agents (Taylor et al., 2012). In that study, subjects showed greater vigilance towards an area from which they had previously witnessed a threatening “stick attack” if a hidden causal agent (a human) could still be present in that area compared to when a human person had visibly left. Interpretations of these results were challenged in two commentaries (Boogert et al., 2013; Dymond et al., 2013). We aimed to replicate this experiment with a different group of NCCs (N = 14) whilst also adding three additional control groups that addressed the issues raised in the two commentaries. These four experimental groups included a direct replication (n = 4), a counter balance of the events of that replication (n = 4), a control group to see if alternative associative cues would create the same effect (n = 3) and finally, a counterbalanced group of these alternative associative cues (n = 3). The direct replication group did not replicate the effect of Taylor et al. (2012). The fact that we did not replicate the effect meant that further interpretation of our other control groups proved difficult. The low sample size of our replication group meant we could not be sure if we did not replicate the effect due to low power or due to actual differences. Our findings neither support nor refute whether NCCs reason about hidden causal agents.
Genoprotective effect of D-Pinitol isolated from aerial parts of Soybean plants against Doxorubicin-induced genotoxicity evaluated by in vitro comet assay in Vero cell lines
Authors: Murugesan Sudha  , Thangarasu Vetrichelvan
Published: May 2021

Doxorubicin is a chemotherapeutic agent with a genotoxic effect on normal cells at its therapeutic dose itself. D-Pinitol is an abundantly available carbohydrate in Soybean plants and has been proven for antioxidant and anti-inflammatory activities. Our investigation was examined by in vitro comet assay to explore the genoprotective effect of D-Pinitol in normal cells against Doxorubicin-induced genotoxicity in Vero cell lines. In vitro comet assay treatment groups were: Vero Cell lines with culture medium (control group), Doxorubicin (0.15μg/ml), D-Pinitol (0.05×103 mM, 0.125×103 mM, and 0.25×103 mM) alone, and pretreatment with D-Pinitol (0.05×103 mM, 0.125×103 mM, and 0.25×103 mM) before Doxorubicin (0.15μg/ml) treatment. When compared to the control group, D-Pinitol alone treated groups showed no significant changes in the percentage of DNA damage. For the evaluation of the genoprotective effect of D-Pinitol, the % DNA damage in the D-Pinitol, and Doxorubicin simultaneously treated groups were compared to the Doxorubicin alone treated group. The results showed that Doxorubicin-induced genotoxic effect in Vero cell lines was significantly reduced by D-Pinitol in a dose-dependent manner by reducing DNA damage. Our findings confirmed that D-Pinitol had no genotoxic effect and it showed a genoprotective effect against Doxorubicin-induced genotoxicity.
Análisis de las variables que influyen en el desbordamiento del río Frío en el municipio de Campoalegre, Huila (Colombia)
Authors: Castañeda Espinosa Mónica Sofia , Camacho Hernández Cindy Johanna , Rativa Ortega Juan Felipe
Published: May 2021

En este estudio se realizó una abstracción teórica de los conceptos básicos sobre meteorología y la medición de cada una de sus variables, además, se analizó cada uno de los datos suministrados por el IDEAM,con el fin de determinar la variable con mayor incidencia en la creciente de la cuenca hídrica del río Frío, con ayuda del programa Weka. De los resultados de la simulación en el software experto en minería de datos,se puede concluir que el factor dominante es la precipitación, debido a que a mayor grado de precipitación es más alto el riesgo de que ocurra una inundación en el municipio de Campoalegre (Huila), y el restode las variables afectarían directamente la precipitación. En esta dirección, este proyecto propone estudiar las causas del desbordamiento del río Frío en la región del municipio de Campoalegre, ocurrido el 22 de febrerode 2017 y que ocasionó daños materiales a la comunidad.
Pengaruh Aplikasi â€œMommy Nifasâ€ terhadap Peningkatan Pengetahuan dan Keterampilan Ibu
Authors: Putri Nopi Anggista , Hilmanto Dany , Zulvayanti Zulvayanti
Published: May 2021

Complications of the puerperium are a contributing factor to the high maternal mortality rate (MMR).Â  One effort to reduce the MMR is to increase the knowledge and skills of mothers regarding postpartum care.Â  This study aims to analyze the effect of using an application that contains information about postpartum care to increase the knowledge and skills of mothers. This study uses a quasi-experimental design with a pre-posttest with a control group design. The subjects of the study were postpartum mothers in the work area of Gadingrejo Public Health Center from September to October 2019 with 60 respondents, consisting of 30 respondents from the treatment group and another 30 from the control group using consecutive sampling techniques.Â  The intervention group is mothers who get the mommy nifas application and the control group is mothers who don't get application data analysis using the chi-square test. The results showed an increase in knowledge after giving higher mommy nifas application which is 71,5 (pre-test) to 93 (post-test) with a value of p-value<0,05.Â  Skills improved from 50 (pre-test) to 70,5 (post-test) with a p-value<0,05.Â  The percentage increase in knowledge after using the application is by 17% and skills by 40% with a value of p-value<0,05. The conclusion of this study is that there is an effect of increasing skills and increasing the percentage of mothers' knowledge after using mommy nifas applications.
Identifikasi Taenia solium secara Mikroskopis pada Peternakan Babi
Authors: Bekti Heri Setiyo , Habibah Nur , Rinawati Luh Putu , Pradnya Yasa Ni Putu Candra Dewi , Rindi Oktavelendi Dhaneta Graha , Dewi Ni Km Ayu Kusuma , Savitri Ni Putu Ayu Dani , Rakhmawati Aprilia
Published: May 2021

Taenia soliumÂ is a zoonosis found all over the world, especially in developing countries.Â T soliumÂ can cause taeniasis and cysticercosis in humans. Pigs as intermediate hosts can be infected withÂ T soliumÂ which causes porcine cysticercosis.Â T soliumÂ can infect muscle, skin, eye, and brain tissue which can develop into neurocysticercosis. Neurocysticercosis is the cause of 30% of cases of epilepsy in the world. In Denpasar city, pigs are one type of livestock. A large number of pig farms and the Balineseâ€™s people's habit of consuming pork is one of the sources ofÂ T soliumÂ infection. This research was conducted to determineÂ T soliumÂ eggs in pig feces. The study was conducted microscopically on 31 samples with simple random sampling technique. The results showed that of the 31 samples examined, 54.8% (17 samples) were positive forÂ T soliumÂ eggs. This indicates that the pig farms in Denpasar city have been infected withÂ T solium. Pig farming in Denpasar city was done traditionally and kept indoors. However, the breeders pay less attention to pig health and environmental sanitation. Also, pigs are slaughtered privately by breeders because there are no slaughterhouses. Lack of supervision of pork circulating in the community is also the cause ofÂ T soliumÂ infection. Therefore, it is necessary to carry out supervision by the local government on pig farms as well as supervision of pork consumed by the public to prevent and eradicateÂ T soliumÂ infection.
Análise da Interação entre o Leitor e o Livro Didático: Um Estudo nos Livros de Ciências dos Anos Iniciais
Authors: Sobrinho Junior Joao Ferreira , Mesquita Nyuara Araújo da Silva
Published: May 2021

O objetivo deste estudo foi identificar as perspectivas de interação entre o leitor e o livro didático por meio das TDIC e, para isso, foram analisados os livros didáticos (LD) de Ciências dos anos iniciais do Ensino Fundamental aprovados no PNLD de 2019. A investigação foi desenvolvida a partir de uma análise documental e bibliográfica que, a partir das 14 coleções aprovadas, distribuídas em 70 livros didáticos, possibilitou a criação de seis categorias de análise que expressam as formas de inserção das TDIC nos materiais estudados considerando-se a frequência com que referências às tecnologias emergem nos textos. Nota-se a presença de seis categorias que evidenciam desde a disponibilidade de links para busca de informações e realização de atividades externas ao livro até a divulgação de imagens relacionadas às TDIC. No movimento de desvelamento destas categorias, propomos que existem dois tipos de perspectivas de interação entre o leitor e os livros didáticos de Ciências analisados. A primeira forma de interação se dá por meio de imagens e textos que direcionam para o próprio livro. A segunda forma de interação refere-se ao direcionamento para que o estudante busque informações externas ao livro didático, no sentido de complementar a formação de caráter científico.
Analysis Of Water Balance Aspect On The Results Of Geo-electric Interpretation With Schlumberger Configuration
Authors: Wulandari Esti , Septoraharjo Eko Rony , Nugroho Laksono Djoko , Hudyantoro Hudyantoro , Oetomo Wateno
Published: May 2021

The background of the problem is that the need for water for various purposes constantly increases in line with the population growth and changes in water use patterns caused by technological advances, industrial growth, and changes in land use. Moreover, from the existing problems, several problem formulations were obtained as the basis for identifying the presumption of groundwater presence, among others, 1). what is the magnitude of the infiltration rate in the study area in relation to the influence of land use conditions, 2). how the results of geo-electric interpretation using the Schlumberger configuration in estimating aquifer layers based on geo-hydrological aspects, and 3). how the effect of time and cost efficiency. Based on the results of the analysis and calculations, several things can be concluded, including: 1). the volume of the infiltration rate using the Horton method (q) by considering the land cover / land use conditions (C), it is known that the average infiltration capacity on the land in the study location per year is more than 200 cm / year, and has an effective enough infiltration capacity so that it is average. -the annual average can store water up to> 200 cm / year, 2). In that area, an aquifer layer was found at a depth of 30-50 meters at the GL 1 point, and the GL point at a depth of 22-55 meters, with the results of the analysis showing the ability of the land to carry out the infiltration process properly and validated from the results of geo-electric investigations, and 3). the results evaluation analysis is able to streamline the amount of operational costs for groundwater source investigations and the time of implementation
Library Considerations for the Colonial Impacts of Indigenous Cookbook Publishing
Authors: Stolz Devon
Published: May 2021

According to Natifs (North American Traditional Indigenous Food Systems), the first action in understanding the Foundations of an Indigenous Food System Model is the “Removal of Colonized Thought.” food sovereignty, physical and spiritual connection to land, and sustainable food practices are interlocked with decolonial action. Considering Traditional Knowledge (TK), as intellectual property, what does it mean for libraries to collect books containing TK, such as cookbooks written by Indigenous authors, published by Indigenous publishers or otherwise dealing with Indigenous Food Systems? Mindful of the colonial impacts on cookbook publishing in Canada, the author proposes a 4-part framework for libraries when acquiring or weeding Indigenous cookbooks to and from their collections. Used as a tool, the framework promotes the stewardship of collections (and metadata) that do not perpetuate colonial violence through language and Eurocentrism, but champion Indigenous authors, publishers, and content. Written from the position of queer-settler, the essay provides examples of published works that meet the criteria of the framework, celebrating Indigenous Food Systems that predate librarianship’s colonial classification. Through personal narrative, the author demonstrates how the offerings of such texts can become integrated into a personal stewardship of the teachings being shared that directly informs the case for equitable collections management.
Museums Without Walls
Authors: Catton Freyja , Smith Laura
Published: May 2021

The purpose of this paper is to explore the possibilities of virtual exhibitions (VEs) for GLAM institutions. While VEs continue to be secondary to physical exhibitions, an effective VE uses technology to engage viewers and present opportunities for interactivity to support further learning and discovery of collection materials. Cultural heritage organizations can use VEs to make the “digital version of a cultural artefact accessible even when the physical access is restricted” and leads GLAM institutions and LIS scholars to reflect on how “users receive and interact with information in a virtual world” (Caggianese et al., 2018, p.625). With the aid of easily accessible additional information, this modern form of presentation may support a deeper level of understanding than a user can experience by viewing a traditional physical exhibition, and may enhance their overall viewing experience. Despite the excitement and opportunities afforded by VR, exhibitions remain accessible for visitors without VR equipment via browsers or web-page based exhibitions. As the “virtual exhibition is a concept that has acquired new meanings along with the evolution of modern information and communication technologies,” we look forward to seeing how GLAM institutions continue to shape the user experience (Ciurea & Filip, 2016, p.28).  Cultural organizations will continue to develop and combine their partnerships, financial and staff resources, content, and visitor interests to build more VE structures that fit both their collections and their community.
Self-Representation and Decolonial Learning in Library Makerspaces
Authors: Zhang Helen
Published: May 2021

This paper explores how Indigenous digital storytelling can be used as a mode for self-representation and decolonial learning in library makerspaces. Digital storytelling involves expressing your lived experiences and stories through a dynamic combination of textual and digital literacies. Implementing Indigenous digital storytelling programs allows library makerspaces to show the value of technology, digital and visual literacy, Indigenous Storytelling, and Ways of Knowing by letting Indigenous Peoples represent themselves and their lived experiences. This paper lays the groundwork on how library makerspaces can incorporate Indigenous approaches to digital storytelling. I argue that creating and implementing Indigenous-centered digital storytelling programs helps decolonize makerspace programming. Using integrative literature review methods, I will qualitatively identify the values of Indigenous Storytelling and digital storytelling to see how they interconnect. I examine how Indigenous Peoples have used digital storytelling and what libraries have done to support digital storytelling and Indigenous Storytelling to explore how these practices can be better adopted by library makerspaces.
Menjaga Eksistensi Usaha Mikro, Kecil, dan Menengah Pada Masa Pandemi Covid-19
Authors: Damayanti Ni Nyoman Sri Rahayu
Published: May 2021

Usaha Mikro, Kecil, dan Menengah (UMKM) merupakan usaha yang mampu membangun perekonomian nasional berdasarkan demokrasi ekonomi yang berkeadilan. Operasional UMKM sangat dipengaruhi salah satunya oleh kondisi pasar. Kondisi pasar menjadi tidak menentu sejak terjadi pandemi Covid-19. UMKM menjadi salah satu usaha yang turut merasakan dampak tersebut. UMKM dinilai kurang memiliki ketahanan dan fleksibilitas dalam menghadapi pandemi ini dikarenakan beberapa hal seperti tingkat digitalisasi yang masih rendah, kesulitan dalam mengakses teknologi dan kurangnya pemahaman tentang strategi bertahan dalam bisnis. Berdasarkan atas permasalahan tersebut, penting untuk dilakukan berbagai tindakan berupa kebijakan-kebijakan untuk menyelamatkan keberlangsungan UMKM di tengah kondisi pandemi. Penelitian ini menggunakan metode kualitatif deskriptif. Berdasarkan atas kajian literatur yang dilakukan, maka terdapat beberapa kebijakan yang dirumuskan oleh pemerintah untuk menjaga eksistensi UMKM di masa pandemi Covid-19. Kebijakan tersebut berikaitan dengan pemberian bantuan langsung kepada UMKM, melakukan restruktrisasi kredit, memberikan insentif pajak, pemberian kredit modal kerja, melakukan pembelian produk UMKM, mengimplementasikan protokol kesehatan di dunia usaha, serta melakukan digitalisasi UMKM.
Pengaruh narsisme dan job stressor terhadap workplace deviance dan kinerja karyawan (studi pada karyawan bank panin cabang malang)
Authors: Ratnasari, SE. MM. Dr. Siwi Dyah , Rahmawati, SE. MM. Dr. Rina
Published: May 2021

The purpose of this study is to determine: 1). The significant effect of narcissism on employee performance, 2). The significant effect of on Workplace Deviance, 3). The significant effect of Job Stressor on Workplace Deviance, 4). Significant influence of Job Stressor on Employee Performance, 5. Significant influence of Workplace Deviance on Employee Performance.The research approach used in this research is quantitative. This type of research is explanatory with the method of collecting data through surveys using a questionnaire. The study population was 52 employees of Bank Panin Branch Malang. The research sample is the same as the total population (saturated sample) The data is analyzed using Path Analysis.The results showed that: 1) Narcissism has a significant effect on employee performance, 2). Narcissism has a significant negative effect on Workplace Deviance, 3). Stres Kerja has a significant negative effect on Workplace Deviance, 4). Stres Kerja has a significant positive effect on Employee Performance, 5). Workplace Deviance has a significant negative effect on Employee Performance.The implication of this research is that the employee's narcissism can improve individual performance. Meanwhile, an increase in Job Stressor within a certain limit has an impact on increasing Employee Performance and decreasing Workplace Deviance
Pengaruh Pemahaman Kewirausahaan Dan Penerapan Teori Planned Behavior Terhadap Minat Berwirausaha
Authors: Respati Agustini Dyah , Santoso Singgih
Published: May 2021

Saat ini kegiatan bisnis, termasuk yang dilakukan banyak wirausahawan, tidak dapat lepas dari pengaruh teknologi informasi, mulai dari proses bisnis (penawaran via internet), proses transaksi via online, komunikasi lewat facebook atau email, sampai pelayanan purna jual yang dapat dilakukan lewat beragam media sosial elektronik atau email (surat elektronik). Penelitian ini bertujuan untuk mengetahui hubungan antara variabel-variabel Entrepeneurial Knowledge, Sikap Berwirausaha, Norma Subyektif, Perceived Behavorial Control dan Minat Berwirausaha dalam sebuah model persamaan struktural. Dengan disain riset survei menggunakan kuesioner pada sejumlah mahasiswa, hail penelitian menunjukkan bahwa variabel Entrepeneurial Knowledge mempengaruhi secara positif dan signifikan pada variabel Sikap Berwirausaha, Norma Subyektif, dan variabel Perceived Behavorial Control; sedangkan sikap berwirausaha positif berpengaruh pada niat berwirausaha. Namun demikian, variabel Norma Subyektif dan Perceived Behavorial Control tidak berdampak signifikan pada niat responden untuk memulai kegiatan wirausaha.
Analyzing The Effect Of Bank Characteristic On Profitability In Banking Companies Listed In Indonesia Stock Exchange
Authors: Serly Serly
Published: May 2021

This research is conducted to analyze the effect of bank characteristics on go public banks’ profitability in Indonesia. Return on asset, return on equity, and net interest margin are dependent variables in this research and involves five types of banking risks (credit, liquidity, security, capital, and insolvency), bank size and diversification, and cost efficiency. Research objects of this research are banking companies listed on Indonesian Stock Exchange (IDX). The research data is financial data issued by IDX from 2014 to 2018. Observation data collected in this research is processed using the regression panel method. The result from this research is that credit risk and insolvency risk has effect on return on asset and return on equity significantly. Liquidity risk, capital risk and bank size don’t have significant effect. Security risk and bank diversification effecting net interst margin significantly. Cost efficiency has effect on profitability significantly.
Experimental investigation of Electro discharge machining process by AHP-MOORA technique
Authors:   Department of Mechanical Engineering, SRKR Engineering College, India, Debnath Shantanu , Ghosh Soumya ,   Department of Electrical Engineering, Mallabhum Institute of Technology, India
Published: May 2021

In the current study, Analytic Hierarchy Process (AHP) combined with Multi-objective optimization by ratio analysis (MOORA) was adopted to find the efficiency of optimizing multiple performance characteristics for EDM of Al-4.5%Cu- SiC composite using a cylindrical copper electrode. The influence of three machine process parameter pulse on (TON), peak current, duty cycle, and one material variable weight fraction on the response variables material removal rate (MRR), electrode wear ratio (EWR), and surface roughness (SR) have been investigated using multi-attribute decision- making model. The response surface methodology (RSM) central composite designs (CCD) have been used as the experiment's design. The weight factors for the output responses assigned by the AHP method and the most desirable significant factor levels determined by the MOORA method. The method implemented in this paper is advantageous in various real-life decision-making problems in the manufacturing environment.
RESUME HUKUM TATA NEGARA PIRDAUS
Authors: PIRDAUS
Published: May 2021

Istilah Hukum Tata NegaraBelanda ( staatrecht ) adalah istilah hukum tata negara dalam bahasa belanda Inggris ( consitutional law )adalah istilah hukum tata negara dalam bahasa inggrisJerman ( varfassungsrect ) adalah istilah hukum tatanegara dalam bahasa jermanPrancis ( droit consitutionel )adalah istilah hukum tata negara dalam bahasa prancisPengrtian Hukum Tata Negara Para AhliVan der votMenurut van der vot Hukum Tata adalah peraturan-peraturan yang menentukan badan-badan yang diperlukan beserta kewenangannya masing-masing serat hubungannya dengan individu warga negara dengan kegiatannya .“bahwa peraturan-pertaturan dan badan-badan di suatu negara harus saling berhubungan satu sama lain, baik individu warag negara mereka harus saling berkaitan dengan yang lain “Cristian van vollenhovenMenurut cristian van vollenhoven Hukum Tata Negara mengatursemua masyarakat hukum atasan dan masyarakat hukum bawahan menurut tingkatannya, dan dari masing-masing itumenentukan wilayah lingkungan masyarakat, badan-badan yang berkuasa,fungsi,susunan dan wewenangmasing-masing dalam lingkungan masyarakat hukum tersebut .“bahwa dalam mengatur peraturan hukum dalam suatu negara harus melihat tingkatan-tingkatannya dan di beri hak masing-masing wilayah untuk menentukan aturan di wilayah lingkungan nya”
Sistem Ekonomi Kapitalisme
Authors: Rafki Mirna
Published: May 2021

Artikel ini terkait dengan seperti apa sistem ekonomi kapitalisme
KEBUTUHAN SPIRITUAL YANG DIBUTUHKAN MANUSIA SEBAGAI MAKHLUK BIOLOGIS, PSIKOLOGIS, SOSIAL DAN SPIRITUAL
Authors: Aulia Tria
Published: May 2021

Kebutuhan spiritual merupakan kebutuhan dasar setiap individu untuk mendapatkan keyakinan, harapan, dan makna hidup. Selama dalam kondisi sehat di mana setiap komponen biologis, psikologis, sosial, kultural, dan spiritual dapat berfungsi dengan baik, sering manusia menjadi lupa, seolah hidup memang seharusnya seperti itu. Tetapi ketika salah satu fungsi komponen tubuh terganggu, maka terjadilah stresor, menuntut setiap orang mampu beradaptasi, pulih kembali dengan berbagai upaya, dan ketika upaya mencari pemulihan tidak membuahkan hasil, disitulah seseorang akan mencari kekuatan lain diluar dirinya, yaitu kekuatan spiritual (Yusuf, 2017). Menurut Puchalski (2009) dalam Nuraeni (2015), menyatakan bahwa tidak semua penyakit dapat disembuhkan namun selalu ada ruang untuk penyembuhan. Penyembuhan dapat dimaknai sebagai penerimaan terhadap penyakit, ketentraman dalam kehidupan, dan spiritual menjadi inti dari penyembuhan. Penyembuhan mengacu pada kemampuan seseorang mendapatkan kebahagiaan, kenyamanan, koneksi, makna, dan tujuan hidup dalam penderitaan maupun rasa sakit yang dialami.
Muh nasim-Resume htn
Authors: Imani Muhammad Nasim Adil Al
Published: May 2021

Hubungan hukum tata negara dengan ilmu lainnyaHubungan tata negara dengan ilmu politik Hukum Tata Negara mempelajari peraturan-peraturan hukum yang mengatur organisasi kekuasaan Negara, sedangkan Ilmu Politik mempelajari kekuasaan dilihat dari aspek perilaku kekuasaan tersebut.Hubungan hukum tata negara dengan ilmu administrasi negara Hukum tata negara memiliki hubungan yang sangat erat dengan hukum administrasi negara. Hukum administrasi negara merupakan tindak lanjut dari hukum tata negara, artinya tugas dan wewenang, fungsi, jabatan badan administrasi di jalankan diatur dalamm hukum administrasi negara.Hubungan Hukum Tata Negara dengan Ilmu Negara. Kedua bidang ilmu tersebut, Hukum Tata Negara dan Ilmu Negara mempunyai hubungan yang sangat dekat, dimana Ilmu Negara memberikan dasar-dasar teoritis kepada Hukum Tata Negara, sedangkan Hukum Tata Negara merupakan konkretisasi dari teori-teori Ilmu Negara.
Muratbekova Sarakul Abishovna (2021). ADVANTAGES OF DISTANCE LEARNING IN A HIGHER EDUCATIONAL INSTITUTION// FUNDAMENTAL AND APPLIED SCIENTIFIC RESEARCH (ICFARS) April 2021, Berlin - Germany: collection of scientific papers / OEAPS OU.; editorial board: Flora Bertrand (editor-in-chief) [and others]. - Tallinn, Estonia: OEAPS OU., 2021. S. 14-19.
Authors: Muratbekova Sarakul Abishovna
Published: May 2021

At present a new system of education is introduced. This system enables people to get knowledge and a good foundation in the sciences basic to his or her field of study. Distance learning has developed over years from satellite video courses to modern videoconferencing through personal computers.
Kuttab itu Pesantren?
Authors: Sofanudin Aji
Published: May 2021

Belakangan ini muncul lembaga pendidikan Islam yang mengusung nama kuttab. Di Jawa Tengah, sudah muncul di kota Semarang, kota Surakarta, Klaten, Kendal, Tegal, Purwokerto, dan kab/kota yang lain. Meskipun demikian, pemerintah (Kemendikbud dan/atau Kemenag) tidak memiliki data base jumlah kuttab di Indonesia. Selama ini, perijinan kuttab beragam, ada yang memiliki ijin operasional (1) sebagai Pusat Kegiatan Belajar Mayarakat (PKBM) di bawah Dinas Pendidikan; (2) sebagai pendidikan kesetaraan tingkat ula di bawah Kementerian Agama; (3) menginduk pada PKBM lain; dan (4) tidak/belum memiliki ijin operasional.
Sistem Ekonomi Kapitalis
Authors: septiani Dian
Published: May 2021

Untuk mengetahui bagaimana itu sistem ekonomi kapitalis
SISTEM EKONOMI KAPITALISME
Authors: m ummu kaltsum.
Published: May 2021

Artikel ini membahas tentang sistem ekonomi Kapitalisme
Sistem Ekonomi Kapitalisme
Authors: Inayah Fitrah Rahma
Published: May 2021

Permasalahan ekonomi yang sering muncul di masyarakat menyangkut tiga masalah pokok yaitu barang ataupun jasa apa yang akan diproduksi. Dalam mengatasi masalah tersebut diperlukannya cara tertentu untuk menjalankan perekonomian negara, cara tersebut dinamakan sistem ekonomi. Sistem ekonomi adalah suatu cara untuk mengatur dan mengorganisasi segala aktivitas perekonomian masyarakat baik yang dilakukan pemerintah atau swasta berdasarkan prinsip tertentu dalam rangka mencapai kemakmuran atau kesejahteraan.
RESUME HUKUM TATA NEGARA AUDHATUL FAIDZ
Authors: Faidz Audhatul
Published: May 2021

Hukum tata negara adalah hukum yang mengatur tata struktu kenegaraa, hubungan antara struktur kenegaraan, dan hubungan antara struktur kenegaraan dengan warga negara. Dalam lingkungan hukum tata negara dikenal beberapa istilah yaitu :
Andi Aditya Riansyah
Authors: Riansyah Andi Aditya
Published: May 2021

Menurut Van der Pot Hukum Tata Negara adalah peraturan-peraturan yang menentukan badan-badan yang diperlukan beserta kewenangannya masingmasing hubungannya satu sama lain, serta hubungannya dengan individu warga negara dalam kegiatannya. Menurut Paul Scholten Hukum Tata Negara adalah het recht dat regelt de staatsorgani satie, atau hukum yang mengatur mengenai tata organisasi negara.
Sistem ekonomi kapitalisti
Authors: Riskayanti.m
Published: May 2021

Sistem ekonomi kapitalis adalah sebuah sistem yg dimna unsur- unsur produksinya dimiliki oleh perseorangan, tokoh pemikir dari sistem ekonomi kapitalis ini adalah Adam Smith.
Ashabul qahfih-Htn
Authors: QAHFIH ASHABUL
Published: May 2021

1.IstilahIstilah hukum tata Negara yaitu serangkaian kaedah hukum yang mengatur susunan alat-alat kelengkapan Negara ,hubungan kekuasaan satu sama lain dan fungsi mendasar. Istilah atau penyebutan hukum tata Negara dari setiap Negara itu berbeda-beda.Antara lain sebagai berikut:-Belanda ;Staatsrecht-Inggris ;Constitusional Law-Jerman ;Verfassungsrecht-Perancis ;Droit Constituonnel2.Pengertian Hukum Tata NegaraPengertian Hukum Tata Negara menurut saya adalah Kumpulan Hukum yang mengatur hubungan,tata organisasi Negara, dan tugas fungsi wewenang dari organisasi Negara.
El razonamiento oracular y los límites de la creencia justificada en los argumentos tipo Gettier acerca del conocimiento
Authors: Matus Alejandro
Published: May 2021

A través de un análisis lógico, mostramos cómo los casos Gettier, presentados como contraejemplos a la concepción del conocimiento como creencia verdadera justificada, no son consistentes, al ser una variación del razonamiento de tipo oracular, falacia lógica en la cual son embrolladas las proposiciones interpretadas, que contienen una constante lógica, con proposiciones formadas por variables lógicas; son confundidas la unicidad con la mera existencia, las condiciones necesarias y suficientes con condiciones necesarias pero no suficientes; y hay sesgos cognitivos, por ejemplo, el de descuido de las frecuencias de base en la argumentación.
Fortbildung to go: Twitter als Ratgeber für Lehrkräfte
Authors: Schröder Sarah , Vochatzer Stefanie , Fischer Christian
Published: May 2021

Digitale Weiterbildungsangebote für Lehrkräfte haben in der Corona-Pandemie neuen Aufschwung erhalten. Auch auf sozialen Plattformen wie Twitter bilden sich immer mehr Lehrkräfte weiter – und das mitunter sogar erfolgreicher als in Präsenzveranstaltungen. Eine wichtige Rolle, die die Fortbildung auf sozialen Medien erst ermöglicht, spielt die fachliche Community.
Các yếu tố tác động đến thái độ người tiêu dùng đối với quảng cáo qua smartphone tại Thành phố Hồ Chí Minh
Authors: Giao Ha Nam Khanh , Dung Thi Thuy
Published: May 2021

Nghiên cứu đánh giá mức độ tác động của các yếu tố ảnh hưởng đến thái độ của người tiêu dùng đối với quảng cáo qua điện thoại thông minh (smartphone) tại Thành phố Hồ Chí Minh, bằng việc khảo sát 290 khách hàng. Phương pháp phân tích Cronbach’s Alpha, phân tích EFA cùng với phân tích hồi quy bội được sử dụng với phương tiện SPSS. Kết quả cho thấy mức độ ảnh hưởng của các yếu tố đến Thái độ của người tiêu dùng TPHCM đối với quảng cáo qua smartphone- theo tầm quan trọng giảm dần: Tính giải trí, Giá trị thông tin, Độ tin cậy, Sự không phiền nhiễu, Sự cho phép và kiểm soát. Nghiên cứu đề ra một số hàm ý quản trị cho các nhà quảng cáo qua smartphone nhằm phục vụ khách hàng tốt hơn, đạt thành công trong kinh doanh.
resume_Nia Ramadani 10200120226
Authors: Ramadani Nia
Published: May 2021

PENGERTIAN RUANG LINGKUP HTN Ruang lingkup htn adalah mengenai organisasi negara yang mencakup lembaga –lembaga negara.hubungan satu dengan yang lain, dan kekuasannya.selain itu, juga mencakup mengenai warga negara terasuk hak asasi manusia [HAM],dan wilayah negara. Dalam kajian dengan ruang lingkup kajian hukum tata negara ,logemann dalam bukunya”hetstaatsrecht van Indonesia”, sepeti di kutip Usep Ranwaidjaja,mengatakan bahwa hukum tata negara adalah hukum mengenai usaha tata negara, yang mencakup dua bidang pokok, yaitu: hukum mengenai kepribadian hukum dari jabatan lain dan hukum mengenai lingkungan kekuasaan negara yaitu lingkungan manusia tertentu, lingkungan wilayah tertentu, dan lingkunganwilayah tertentu.HUBUNGAN HTN DAN LAIN NYAHukum tata negara adalah hukum yang menganut semua masyarakat hukum atasan dan masyarakat hukum bawahan menurut tingkatan masing-masing masyarakat hukum itu menentukan wilayah lingkungan rakyat dan menentukan badan-badan serta fungsi nya masing-masing yang berkuasa dalam masyarakat hukum itu.1. Hubungan tata negara dengan ilmu negara. Kedua bidang ilmu tersebut, hukum tata negara dengan ilmu negara mempunyai hubung
UTILIZATION OF TECHNOLOGY IN LEARNING ENGLISH IN THE PANDEMIC COVID-19
Authors: Marzuki Abdul Gafur , Santiana Santiana
Published: May 2021

The use of technology in the learning process both inside and outside the classroom, both online and offline plays a crucial role. Technology plays a role as a medium in carrying out interactions between lecturers as teachers and students as students in the application of learning, especially online learning during the Covid-19 pandemic. Technology plays an important role in facilitating lecturers in preparing learning materials so that the process can take place even if not face to face. However, the process of implementing online learning does not escape from various obstacles, and the biggest obstacle that is a challenge for learning practitioners is related to the readiness of facilities and the ability of lecturers to use learning technology applications. The implementation of training related to the use of technology applications in learning can be a solution in facing some of the challenges of online learning during the Covid-19 pandemic
HUKUM TATA NEGARA AUDHATUL FAIDZ
Authors: Faidz Audhatul
Published: May 2021

Hukum tata negara adalah hukum yang mengatur tata struktu kenegaraa, hubungan antara struktur kenegaraan, dan hubungan antara struktur kenegaraan dengan warga negara. Dalam lingkungan hukum tata negara dikenal beberapa istilah yaitu :Belnada : “staatsrecht” –staatsrecht in ruimere zin Inggris : “constitutional law” dikarenakan unsur konstitusinya yang lebihPrancis : droit constitutonaelJerman : verfassungrsrecht
Hydroclimatic Analysis of Rising Water Levels in the Great Rift Valley Lakes of Kenya
Authors: Herrnegger Mathew , Stecher Gabriel , Schwatke Christian , Olang Luke
Published: May 2021

Study RegionThe Great Rift Valley lakes of Kenya have recently experienced significant increases in their water levels, negatively impacting the local communities. This has provoked renewed concerns about the causations, with various geological, anthropogenic and hydro-climatic influences hypothesized as potential causes of the water level rises. Study FocusThis study analyses and documents water level fluctuations in Lakes Baringo, Bogoria, Nakuru, Solai, Elementaita and Naivasha. Hydrometeorological analyses are undertaken to understand potential causes and lake volume data is used to derive the “Integrated Catchment Response” (ICR), a magnitude which allows to relate changes in water balance components to signals observed in the lake volume changes.New Hydrological Insights for the RegionCompared to 1984-2009, the recent increases in lake areas range from 21% for Lake Naivasha to an extraordinary 123% for Lake Solai. Mean annual rainfall for 2010-2020 increased by up to 30%. Actual evapotranspiration also increased, but to lesser extent compared to rainfall. The results illustrate that changes in catchment properties due to anthropogenic influences or changes in underground permeability are not necessary to explain the lake level rises. Based on the ICR only surprisingly minor changes in the water balance are necessary to explain the lake level rises, since an increase of only 0.4 - 2% of mean annual effective rainfall leads to the observed phenomena.
The gap between atmospheric nitrogen deposition experiments and reality
Authors: Bebber Daniel
Published: May 2021

Anthropogenic activities have dramatically altered the global nitrogen (N) cycle. Atmospheric N deposition, primarily from combustion of biomass and fossil fuels, has caused acidification of precipitation and freshwater and triggered intense research into ecosystem responses to this pollutant. Experimental simulations of N deposition have been the main scientific tool to understand ecosystem responses, revealing dramatic impacts on soil microbes, plants, and higher trophic levels. However, comparison of the experimental treatments applied in the vast majority of studies with observational and modelled N deposition reveals a wide gulf between research and reality. While the majority of experimental treatments exceed 100 kg N ha-1 y-1, global median land surface deposition rates are only around 1 kg N ha-1 y-1 and only exceed 10 kg N ha-1 y-1 in certain regions, primarily in China. Experimental N deposition treatments are in fact similar to mineral fertilizer application rates in agriculture. Some ecological guilds, such as saprotrophic fungi, are highly sensitive to N and respond differently to low and high N availability. In addition, very high levels of N application cause changes in soil chemistry, such as acidification, meaning that unrealistic experimental treatments are unlikely to reveal true ecosystem responses to N. Hence, despite decades of research, past experiments can tell us little about how the biosphere has responded to anthropogenic N deposition. A new, and more realistic, approach is required if experimental studies are to contribute to our understanding of this important phenomenon.
A Process × Domain Assessment of Narcissism: The Domain-Specific Narcissistic Admiration and Rivalry Questionnaire
Authors: Grosz Michael P. , Hartmann Isabel , Dufner Michael , Leckelt Marius , Gerlach Tanja M. , Rauthmann John F. , Denissen Jaap J. A. , Küfner Albrecht , Back Mitja D
Published: May 2021

Research on grandiose narcissism distinguishes between self-promotional processes (i.e., narcissistic admiration) and other-derogative processes (i.e., narcissistic rivalry; Back et al., 2013). Moreover, research has begun to assess and investigate narcissistic manifestations in different domains (e.g., communal narcissism). To integrate these two lines of research, we developed the Domain-Specific Narcissistic Admiration and Rivalry Questionnaire (D-NARQ), a 72-item narcissism questionnaire that contains a self-promotional (narcissistic admiration) process scale and an other-derogatory (narcissistic rivalry) process scale for four domains: intellectual ability, social dominance, communal care, and physical attractiveness. We investigated the psychometric properties of the D-NARQ in a large online study (N = 1,635). Model fit statistics were largely in line with the theorized factor structure. The measurement precision of the D-NARQ scales were good to very good, and their correlations with established narcissism scales, the Big Five personality traits, and comparative self-evaluations largely supported their convergent and discriminant validity.