bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Lesson Study Berbasis Musyawarah Guru Mata Pelajaran Guru IPA SMP Kabupaten Ogan Ilir
Authors: Riyanto Riyanto , Tibrani Mgs. M. , Anwar Yenny , Destiansari Elvira , Dewi Safira Permata , Anggraini Nike , Amizera Susy
Published: May 2023

Proses pembelajaran dan mengajar (PBM) pada umumnya luput dari perhatian wali murid dan pihak-pihak lain yang terkait. Wali murid terkadang menuntut pendidikan untuk anak-anaknya adalah pendidikan yang berkualitas. PBM yang dilakukan oleh guru tidak ada yang tahu atau hanya guru itu sendiri. Siswa terkadang tahu tetapi untuk menyatakan kekurangan dari setiap guru tidak dapat menyampaikan pesan. Tentu saja kami sebagai pihak yang mengajar di Pendidikan biologi FKIP Unsri terpanggil secara moral ikut ambil bagian merubah kondisi ini. Salah satunya melalui Lesson Study (LS) berbasis MGMP guru IPA di kabupaten Ogan Ilir.Tujuan dan manfaat dari kegiatan pengabdian masyarakat (PM) ini adalah untuk meningkatkan kemampuan guru IPA SMP menguasai materi IPA, mengajar, membuat perangkat pembelajaran dan  dapat percaya diri serta terampil membimbing praktek IPA di laboratorium sekolah. Pelaksanaan kegiatan PM diperlukan beberapa tahap sebagai berikut: Tahap persiapan, tahap pelaksanaan dan tahap evaluasi. Dari kegiatan PPM tentang pelatihan LS Berbasis MGMP IPA SMP Kabupaten Ogan Ilir dapat disimpulkan bahwa kegiatan LS sangat berpotensi meningkatkan profesionalisme guru IPA SMP Ogan Ilir, sebab dapat meningkatkan kemampuan guru IPA SMP menguasai materi IPA, meningkatkan keterampilan PBM guru IPA dan meningkatkan kemampuan membuat perangkat pembelajaran di sekolah. Melalui kegiatan pengabdian masyarakat diharapkan MGMP guru IPA dapat menemukan metode atau model meningkatkan profesionalisme guru IPA SMP kabupaten Ogan Ilir.
Pelatihan Wirausaha Generasi Z Terutama Siswa/I SMA St. Agnes Untuk Mengembangkan Potensi Entrepreneur Muda Melalui Zoom
Authors: Mettan Santho Vlennery , Setiawan Yan Christianto
Published: May 2023

Program yang diciptakan atau di buat oleh tingkatan Pendidikan di sekolah-sekolah SMA, khususnya SMA St. Agnes untuk menciptakan para entrepreneur muda yang paham akan kewirausahaan dan memiliki karakter dan mental seorang entrepreneur. Selanjutnya permasalahan yang muncul dari terciptanya program ini yaitu kurangnya staff pengajar yang terlatih atau yang paham dan mampu untuk melaksanakan Pendidikan kewirausahaan, khususnya di Sekolah SMA St. Agnes. Permasalahan inilah yang bisa memberikan peluang bagi perguruan tinggi untuk membantu memberikan aksi nyata untuk membantu mengembangkan para generasi muda dalam membangun dan menciptakan karakter dan mental seorang entrepreneur, serta membantu untuk memberikan pemahaman yang lebih detail dan nyata mengenai kewirausahaan melalui pengabdian kepada masyarakat. Sebagai bentuk kerjasama tersebut maka Dosen Fakultas Kewirausahaan Unika Widya Mandala Surabaya akan mengadakan pendampingan dan pemberian pelatihan bagi para siswa-siswi SMA St. Agnes Surabaya, juga sekaligus bagi tenaga pengajar yang akan mendampingi para siswa-siswi SMA St. Agnes Surabaya. Pelatihan dan pendampingan ini akan dilakukan sebanyak 14 kali pertemuan selama 7 bulan pembelajaran. Setiap bulannya akan diadakan 2 kali pelatihan yang diadakan pada setiap akhir minggu dari bulan tersebut. Hasil dari Pengabdian ini dimana para siswa-siswi ini akan memiliki tambahan wawasan baru dalam mencari ide untuk menciptakan sebuah bisnis yang dapat diliat dari berbagai macam aspek, seperti aspek local wisdom, aspek pemasaranan, dan aspek konsumen. Selain itu juga, siswa-siswi SMAK St. Agnes juga sudah dibekali dengan pengetahuan untuk melakukan kuesioner yang akan digunakan untuk analisis pasar dalam memahami konsumen dari ide bisnis yang akan dijalankan oleh siswa-siswi SMAK St. Agnes.
Sosialisasi Edukasi Sasaran Keselamatan Pasien (Patient Safety) Pada Perawat di Rumkit Tk. II Dr.Prof. J. A. Latumeten
Authors: Tunny Hasna , Tauran Ireine
Published: May 2023

Keselamatan pasien (patient safety) adalah masalah kesehatan yang menjadi perhatian global, tujuan utama keselamatan pasien adalah untuk mencegah hal-hal yang merugikan pasien serta mengatasi dampak yang tidak dapat dihindarkan efek samping. Sasaran keselamatan pasien (patient safety) meliputi identifikasi pasien, komunikasi efektif, keamanan obat-obatan yang diwaspadai, memastika lokasi pembedahan, (prosedur dan tepat pasien), mengurangi resiko infeksi dan mengurangi resiko cedera akibat pasien jatuh. Maka berdasarkan analisis Tim Pengabdi di Rumkit Tk. II Dr.Prof. J. A. Latumeten untuk memberikan sosialisasi sasaran keselamatan pasien dengan sasaran adalah perawat dengan metode ceramah dan tanya jawab. Adapun hasil terkait pengetahuan perawat tentang sasaran keselamatan pasien meningkat (post-test) 94%. Pengetahuan dominan baik, pemahaman masing – masing pribadi inilah kemudian diharapkan dapat diimplementasikan dalam asuhan keperawatan pasien dalam mengidentifikasi pasien dengan benar, mengurangi resiko infeksi dengan kepatuhan mencuci tangan 5 moment serta mengurangi resiko cedera lebih baik lagi guna meningkatkan mutu pelayana.
Peran Posyandu Dalam Meningkatkan Kesehatan Ibu dan Anak di Desa Cipetir, Kabupaten Sukabumi
Authors: Lestari Dewi , Akbar Fachry , Nurfadilah Lisna , Vacsal Muhammad Ryan , Meha Raihan Islami , Agustrianti Santi , Fauziah Sopiatunnisa
Published: May 2023

Penelitian ini mengkaji tentang Peran Posyandu dalam Meningkatkan Kesehatan Ibu Dan Anak Di Desa Cipetir, Kabupaten Sukabumi. Dengan tujuan untuk meningkatkan kesehatan masyarakat lewat posyandu dengan mengetahui Persepsi masyarakat terhadap Program Posyandu, Peran posyandu dalam meningkatkan kualitas kesehatan ibu dan anak, dan Kendala  serta solusi posyandu dalam meningkatkan kesehatan masyarakat, kajian ini mengunakan metode kualitatif dan teknik pengumpulan data melalui wawancara, observasi, Focus Group Discussion, Participatory Rural Appraisal (PRA), dan studi pustaka. Narasumber dalam penelitian ini adalah, para kader PKK Desa, para kader posyandu,dan para anggota posyandu. Hasil penelitian menujukkan bahwa persepsi sebagian kecil masyarakat terhadap Program Posyandu cukup postif, sedang sebagian besar beranggapan negatif terhadap Posyandu akibat kepercayaan masyarakat terhadap mitos-mitos yang ada. Menyikapi hal ini, Peneliti melakukan tiga program yaitu sosialisasi, home care, dan posyandu award sebagai motivasi kader, dan terobosan dalam meningkatkan kesadaran warga dimana posyandu memiliki peranan penting dalam meningkatan kualitas kesehatan ibu dan anak melalui proses pelayanan kesehatan.
Pelatihan Konselor Kreator untuk Meningkatkan Kualitas Layanan Bimbingan dan Konseling Berbasis Digital
Authors: Prihatiningsih Riskiyana , Simon Irene Maya , Janu Setyowati Arbin , Apriani Rizka
Published: May 2023

Layanan Bimbingan dan Konseling (BK) dengan media tentunya membutuhkan penggunaan dan pemanfaatan teknologi sehingga proses layanan dapat diterima dengan baik oleh siswa. Peningkatan kualitas layanan berbasis digital yang menarik dan dekat dengan tren yang diikuti oleh siswa. Menjadi konselor kreator, membutuhkan sebuah usaha dan pelatihan untuk mampu membuat layanan yang dekat dengan siswa dan menarik bagi siswa. Pelatihan konselor kreator untuk meningkatkan kualitas layanan BK berbasis digital merupakan upaya penyelesaian masalah yang ditawarkan dalam kegiatan pengabdian ini dengan memberikan kegiatan pelatihan kepada MGBK SMA Kota Malang. Pelatihan dilakukan secara berkala dengan kombinasi pertemuan daring dan luring dan intensive coaching melatih konselor menjadi konselor creator. Secara kesuluruhan berdasarkan hasil angket evaluasi yang diisikan oleh 8 orang dari 15 peserta pelatihan menyatakan bahwa pelatihan sangat menyenangkan dengan presentase 55,6% sangat menyenangkan dan 44,4% menyenangkan, dengan fasilitator yang cukup jelas dalam menyampaikan materi dengan metode yang tepat dengan presentase 55,6% sangat jelas dan 44,4% jelas. Sehingga konselor dapat mengembangan konten layanan BK berbasis digital berupa skenario konten layanan, video, dan microblog. Selanjutnya peserta pelatihan menyatakan bahwa pelatihan ini sangat memberikan manfaat dalam membantu konselor dalam mengembangkan media layanan BK.
Pelatihan dan Pendampingan Diversifikasi Produk Penanganan Sampah Rumah Tangga Bagi Santri
Authors: Slamet Mulyati Sri , Irmawartini Irmawartini , Pujiono Pujiono
Published: May 2023

Pondok pesantren merupakan salah satu fasilitas umum di bidang pendidikan. Setiap fasilitas umum termasuk pondok pesantren wajib melakukan pengawasan kesehatan lingkungannya. Penyehatan tanah dan pengelolaan sampah padat merupakan upaya meningkatkan kualitas lingkungan. Apabila mengacu pada idealisme regulasi, sampah tidak boleh dibuang melainkan dikelola. Upaya minimal pengelolaan sampah minimal 3 R yaitu Reuse, Reduce, dan Recycle. Komposting merupakan salah satu contoh pengolahan sampah sederhana yang bisa diterapkan di lingkungan pondok pesantren. Para santri pondok pesantren Al-Musyahadah yang terbagi ke dalam 4 Pokja ( Kelompok Kerja) mampu melakukan komposting dengan metode Takakura setelah sebelumnya diberikan contoh oleh tim pengabdian masyarakat. Secara umum pengetahuan pengelolaan sampah para santri sudah sangat baik dengan nilai rerata 84,66%. Partisipasi santri laki-laki dan perempuan juga sangat baik yang ditunjukkan dengan keikutsertaan saat pengisian kuesioner, penyuluhan, demo alat, dan praktik komposting sampai menghasilkan kompos jadi. Perlu dilengkapi pelatihan sederhana lainnya seperti manajemen pemasaran produk kompos jadi dan cara packagingnya yang menarik sehingga menjadi “value” bagi pondok pesantren.
Upaya Pemberdayaan Kelompok Wanita Pesisir Poklahsar Dikranusa Melalui Pemanfaatan Ikan Hasil Tangkapan Sampingan di Kelurahan Banten, Kecamatan Kasemen, Kota Serang, Provinsi Banten
Authors: Irnawati Ririn , Surilayani Dini
Published: May 2023

Ikan hasil tangkapan sampingan (HTS) merupakan ikan non target yang ikut tertangkap pada alat tangkap. Jumlah ikan HTS cukup besar berkisar 25-74% dari total ikan hasil tangkapan. Ikan HTS hingga kini masih menjadi problem dan tantangan dalam pengelolaan perikanan karena minim pemanfaatan. Hal ini diperparah dengan pandemic covid-19 yang berlarut-larut yang menyebabkan permintaan ikan menurun, sehingga jumlah ikan yang tidak termanfaatkan menjadi bertambah. Salah satu upaya yang dapat dilakukan adalah dengan diolah menjadi produk olahan, diantaranya pemindangan. Kegiatan pengabdian ini dilakukan dengan metode pelatihan dengan mitra Poklahsar Dikranusa. Mitra sasaran diberikan pelatihan dan pendampingan hingga mampu dan bisa memproduksi pindang secara mandiri. Tahap pembuatan pindang adalah penyiangan ikan; ikan dibungkus dengan daun pisang dengan diberi garam; ikan disusun dalam panci dan direbus selama 1,5-2 jam; pengangkatan ikan yang telah matang; dan pengemasan produk pindang. Pemindangan dapat menjadi alternatif kegiatan ekonomi tambahan bagi wanita pesisir diluar waktu melakukan pekerjaan domestik dan membantu suami memperbaiki jaring. Pemindangan ikan membutuhkan peralatan yang sederhana dan mudah dilakukan, sehingga dapat menjadi sumber penghasilan baru bagi wanita pesisir. Mitra telah mampu memproduksi, mengemas dan menjual produk pindang yang dihasilkan. Nilai ekonomi dari produk ikan pindang jauh lebih tinggi dibandingkan jika hanya menjual ikan segar.
Metode Benchmarking untuk Meningkatkan Produksi Jambu Madu Deli Hijau (Syzygium Aqueum) Sebagai Model Pemberdayaan
Authors: Budi Aldi Setya , Nurlaela Siti , Yulianto Gunawan
Published: May 2023

Jambu madu deli merupakan komoditas yang sangat potensial di pasar, namun petani belum mampu memenuhi kebutuhan pasar karena produktivitas yang rendah. Kajian ini bertujuan untuk mengetahui penerapan teknologi di kebun jambu air madu deli hijau milik Bapak Ruswanto. Kegiatan pemberdayaan dilaksanakan pada Januari – Juli 2022, menggunakan metode deskriptif kualitatif dengan sumber data primer (wawancara, observasi partisipatif, dan FGD) dan data sekunder (dokumentasi). Proses pemberdayaan diawali dengan melakukan perbandingan/benchmarking untuk mengetahui penerapan teknologi pada petani yang lebih maju.  Hasil pemberdayaan menunjukkan bahwa dalam proses perbanyakan tanaman, persiapan media tanam. pengairan, dan pemupukan Keboen Hijau lebih unggul daripada Kebun Pak Ruswanto. Pada aspek penanaman, dan pembungkusan Pak Ruswanto lebih unggul. Pada aspek penyiangan, pemangkasan, pengendalian hama, dan pemanenan sama. Rencana peningkatan produksi dilakukan pada aspek yang masih kurang. Pemberdayaan masyarakat yang ada di sekitar kebun Pak Ruswanto dilakukan dengan pelatihan stek dan memberikan bibit gratis dan sarana awal untuk memulai usaha. Rencana pemasaran dilakukan seacra bersama-sama berbasis kelompok tani.
Optimalisasi Peran Pemuda Sebagai Kader Kesehatan Dalam Upaya Edukasi Gizi dan Perilaku Hidup Bersih dan Sehat di Komunitas Wonosobo Sehat
Authors: Prasetyo Teguh Jati , Nur Khoiriani Izzati , Andini Surjati Katri , Hendra Wijaya Triyadi , Widanita Neva , Hasanah Laeli Nur
Published: May 2023

Indonesia masih menghadapi tingginya angka kematian ibu dan anak, yang diakibatkan oleh permasalahan gizi, penyakit infeksi, serta masalah kehamilan.  Data menunjukkan bahwa prevalensi status gizi balita gizi buruk sebesar 3,9%, gizi kurang 13,8% dan gemuk sebesar 8%. Prevalensi status gizi (indikator TB/U) anak dengan kategori stunting 30,8%.   Masa 1000 Hari pertama kehidupan merupakan periode yang sangat penting sejak janin sampai usia dua tahun. Jika pemenuhan gizi pada masa tersebut baik, maka proses pertumbuhan dan perkembangan dapat optimal. Status gizi balita dipengaruhi oleh banyak faktor diantaranya penyakit infeksi, asupan makan, pengetahuan ibu, usia penyapihan, berat badan lahir, pemberian makan terlalu dini, pola asuh, kesehatan lingkungan dan pelayanan kesehatan. Wonosobo sehat merupakan komunitas para relawan yang peduli terhadap masalah kesehatan. Fokus kegiatan yang dilakukan adalah edukasi dan promosi kesehatan pada empat bidang yaitu gizi, penyakit menular dan tidak menular, kesehatan mental serta kesehatan lingkungan.  Kegiatan ini bertujuan untuk mengoptimalisasi peran pemuda dalam melakukan edukasi kepada masyarakat mengenai kesehatan optimal. Ada tiga tahapan kegiatan yaitu: 1) Tahap penyusunan Media dan Materi pelatihan untuk pendampingan relawan; 2) Tahap Traning Of Trainer bagi relawan Wonosobo sehat tentang Core skill relawan; 3) Tahap workshop dan pemeriksaan kesehatan gratis oleh relawan Wonosobo sehat Bersama tim pengabdi.
Penguatan Masyarakat Melalui Pengorganisasian dan Peningkatan Organisasi PKK dalam Memanfaatkan Limbah Sawit
Authors: Tjilen Alexander Phuk , Tambaip Beatus , Waas Ruloff Fabian Yohanis , Moento Paul Adryani , Purnama Erwin Nugraha
Published: May 2023

Gerakan masyarakat ini bertujuan untuk memperluas informasi dan keterampilan organisasi PKK dalam mengawasi tandan dan menyiapkan limbah sawit dan hewan. Tindakan ini didorong oleh kondisi Kampung Muting, sebagai kawasan yang berkembang pesat di wilayah Merauke. Wilayah Ini merupakan salah satu sasaran yang paling utama untuk diaktualisasikan secara serius dan serius dalam kebijakan perbaikan kelapa sawit di Merauke. Kondisi ini memiliki sasaran untuk ibu ibu rumah tangga. Muncul alamat bagaimana limbah kelapa sawit bisa dimanfaatkan? Untuk menjawab pertanyaan tersebut, dilakukan latihan persiapan dan penyuluhan dengan menggunakan metode persiapan dan penyuluhan administrasi terbuka dan Teknologi Tepat Guna (TTG) dilakukan dalam tandan dengan materi pengetahuan administrasi, administrasi dan inovasi limbah kelapa sawit dan hewan. Hasil berupa Pertama-tama, informasi dan kemampuan untuk mengawasi tandan. Kepiawaian dalam menangani limbah sawit dan ternak menjadi piring, tikar, briket dan pupuk. Perlakuan pemanfaatan limbah ini diharapkan dapat menjadi alternatif upah rumah tangga masyarakat dan petani kelapa sawit mandiri, terutama di tengah masa restorasi kelapa sawit (replanting).
Pemanfaatan Teknologi Informasi dalam Mendukung Perkembangan UMKM (Nyong Group)
Authors: Pratama Irfan , Suria Ozzi , Chandra Albert Yakobus , Prasetyaningrum Putri Taqwa
Published: May 2023

Tantangan yang dihadapi pelaku UMKM terkait teknologi adalah pemahaman atau pengetahuan mereka tentang teknologi, hingga pemanfaatan teknologi yang dapat bermanfaat bagi perkembangan bisnis mereka. Dari sisi teknologi informasi, pertumbuhan data secara digital menjadi sangat masif. Dari aspek sederhana seperti pencatatan penjualan ataupun platform perdagangan pun saat ini sudah beralih ke model digital. Itu artinya, setiap apapun yang tercatat akan tersimpan dan dapat kemudian digunakan untuk kepentingan kemajuan usaha. Data tersebut dapat diolah menjadi informasi dan kemudian dapat menjadi pengetahuan bagi pelaku bisnis dalam menentukan perencanaan strategis mereka. Dari permasalahan yang telah dikemukakan sebelumnya, kegiatan pengabdian kepada masyarakat ini dimaksudkan untuk memberikan pengetahuan terhadap mitra terkait potensi dari data-data yang telah mereka miliki dan memberikan edukasi terkait bagaimana cara data tersebut dapat diolah untuk kepentingan kemajuan bisnis mereka. Dari kegiatan-kegiatan yang telah dilaksanakan dapat disimpulkan bahwa awalnya mitra belum memahami terkait pemanfaatan data yang dapat menjadi nilai tambah bagi bisnis mereka jika mereka mengolah data-data tersebut. Ditunjukan dari perubahan grafik yang diukur menggunakan kuisioner sederhana sebelum dan sesudah kegiatan diskusi. Kemampuan dasar penggunaan teknologi dari mitra sudah cukup baik. Namun belum pernah menggunakan piranti yang digunakan pada pelatihan yang diikuti. Sehingga terjadi peningkatan pemahaman secara teknis maupun teoritis dari mitra.
Penggunaan Deep Eutectic Solvent dalam Penurunan FFA Minyak Jelantah serta Pengaruh Kecepatan dan Waktu Pengadukan
Authors: Dzakiroh Ayu , Rahmadina Nisa , Syarif Aida , Fatria Fatria , Rusnadi Irawan , Erlinawati Erlinawati
Published: May 2023

Biodiesel merupakan salah satu sumber energi alternatif yang dapat di perbaharui dan mampu untuk mengurangi ketergantungan energi nasional terhadap energi fosil. Biodiesel diproduksi dari minyak tumbuhan atau lemak hewan. Minyak nabati yang dapat digunakan sebagai bahan baku adalah minyak jelantah. Minyak jelantah mengandung asam lemak bebas atau Free Fatty Acid (FFA) yang tinggi. Penurunan kadar FFA dilakukan melalui cara ekstraksi menggunakan DES yang terbuat dari campuran Choline Chloride dan Ethylene Glycol dengan rasio molar 1:2. Dalam penelitian ini dlakukan variasi rasio molar Minyak Jelantah:DES sebesar 1:1, 1:2, 1:3, dan 1:4, variasi kecepatan pengadukan 150 rpm dan 300 rpm, dan variasi waktu selama 60 menit dan 120 menit pada suhu 60oC. Hasil penelitian menunjukkan bahwa rasio molar terbaik adalah 1:4, kecepatan pengadukan 300 rpm, dan waktu selama 120 menit dengan penurunan FFA hingga 0,55%.
Intentional ricin intoxication: A case report and review of the literature
Authors:   Department of Internal Medicine, Northwest Clinics, Alkmaar, the Netherlands., P Hendriks Mathijs
Published: May 2023

Background: Ricin is considered one of the most potent toxins worldwide. Several case reports of intentional ricin intoxication have been described. Symptoms are mainly gastro-intestinal and may lead to hypovolemia and organ failure.
Severe Ankyloglossia and its Surgical Management: Case Report
Authors:   University of Hassan II of Casablanca, Casablanca, Morocco, Belfellah Samia
Published: May 2023

Ankyloglossia or tongue-tie is a singularly congenital case qualified by a specific no elastic and dense frenum within lingual muscle. Also it’s occurs when there is an union of the tongue’s body to the mouth’s floor, reducing her motion [1]. Its prevalence ranged of 0.02% to 12%. Lack of unified consensus may explain these rates changing on prevalence of ankyloglossia [2]. A higher incidence revealed in studies exploring neonates in comparison to those realized in other population was revealed by Reddy et al. 2014 [3]. The authors suggested the resolution of beginner variants of ankyloglossia during development justifying the age related difference of prevalence [4].
Peripheral Ameloblastoma of the Mandible: A Rare Case Report
Authors:   University of Siena, Viale M. Bracci 16, Siena 53100, Italy, Pignataro Laura Viola
Published: May 2023

Ameloblastoma represents 1% of all oral tumors and 11% of odontogenic tumors. They are located much more frequently on mandibular bone, rather than maxillary bone, more often in the posterior region instead of the anterior one, except for the African black race which is localized more frequently at the symphysis. It’s extremely rare to find these tumors in extra-mandibular locations, because of the association between their etiology and dental structures.
IHC-Based Gene Expression Analysis Predicts Response to Neoadjuvant Chemotherapy for Bladder Cancer
Authors:   Lanzhou University Second Hospital, No.82 Cuiyingmen Lanzhou, Gansu province, China, Yang Li
Published: May 2023

Objectives: To explore the related genes and clinical characteristics of neoadjuvant chemotherapy (NAC) in bladder cancer, and to establish the prediction model of NAC response.Methods: We downloaded the clinical information and gene expression detected by IHC of 149 patients from the attachment of published paper. Patients were divided into three groups according to different pathological reactions of NAC.
A Novel Application of Anterior Chamber Cells and Aqueous Humor Cytokines Analysis in Uveitis-Glaucoma-Hyphema (UGH) Syndrome: A Case Report
Authors:   Shandong Academy of Eye disease Prevention and Therapy, No. 48#, Yingxiongshan Road, Jinan, 250002, P. R. China, Bi Hongsheng
Published: May 2023

Background: Uveitis-glaucoma-hyphema (UGH) syndrome could be identified by clinical history and detailed ophthalmologic examination. In order to better understand the pathological processes of UGH syndrome, we introduced findings of enhanced red blood cells (RBCs) and inflammatory factors expression in a case of an UGH syndrome.
Three-Dimensional Interactive Quantitative Surgical Planning with Complete Thoracoscopic Lateral Basal Segmentectomy
Authors:   The First College of Clinical Medical Science, China Three Gorges University, No.183 Yiling Road, Yichang, Hubei, 443000, China, Zhang Songlin
Published: May 2023

Objectives: Thoracoscopic segmentectomy for the lateral basal segment (S9) is one of the most technically challenging anatomical segmentectomy. This study aimed to describe thoracoscopic segmentectomy of S9 or S9b using three-dimensional (3D) interactive quantitative surgical planning through inferior pulmonary ligament approach.
Glial Heterotopia Nasal Septum in an Adult: A Case Report
Authors:   The First Affiliated Hospital of Dali University, Dali, 671000, Yunnan, China, Yu Deshun
Published: May 2023

We report a case of Heterotopia of nasal neuroglia from the right nasal septum in a middle-aged man. This Heterotopia is a very rare Heterotopia in the nasal cavity. It presents as a mass of extracranial brain tissue that is not connected to the brain. It often occurs in neonates and children, and is extremely rare in adults.
Percutaneous Nerve Block Catheter; A Novel Minimal Invasive Treatment for Patients with Abdominal Cutaneous Nerve Entrapment Syndrome (ACNES)
Authors:   Laurentius Hospital Roermond, Mgr Driessenstraat 66043 CV Roermond, The Netherlands, Heemskerk Jeroen
Published: May 2023

Anterior cutaneous nerve entrapment syndrome (ACNES) is a commonly overlooked [1] and ill understood cause of abdominal pain resulting in unnecessary, costly and potentially harmful diagnostic procedures. The pain is often severe and can have a debilitating effect on the patient’s quality of life.
Effect of Surgery Combined with Gemcitabine and Oxaliplatin Chemotherapy on Primary Signet Ring Cell Carcinoma of Bladder: A Case Report
Authors:   The First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, Zhou Wensheng ,   China
Published: May 2023

Background: Primary signet ring cell carcinoma of the bladder is an extremely rare and highly invasive variant of primary bladder cancer. When tumors are found, they usually show high level and high-stage lesions and diffuse invasion of the bladder wall, and most tumors do not grow in the cavity. Most patients have no specific symptoms at the beginning, which leads to delayed diagnosis and treatment and poor prognosis.
Bone Marrow Derived Cells Mediated Regulation of Schwann Cells Proliferation and Migration In vitro
Authors:   The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China, Yan Jun , Wu Min ,   The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China
Published: May 2023

Schwann cells (SCs) are the unique glial cells in the peripheral nerve. After peripheral nerve injury, SCs change their morphology, function, and play a new role as repair cells, through this process, factors that enhance SCs proliferation and promote SCs migration will benefit nerve regeneration and functional recovery. Bone marrow-derived cells (BMDCs), which has been proved to offer several regenerative benefits for tissue and organ injuries. However, whether BMDCs support nerve regeneration by affect the proliferation and migration of SCs, remains unclear. Here, we taken BMDCs co-cultured with nerve segments, and then investigated the proliferation and migration of SCs In vitro. Results demonstrated that BMDCs can enhance the proliferation of SCs, and then promoted SCs migration, forming Bungner’s brand-liked structure In vitro. These finding provide a potential new method for repair of injured peripheral nerves in clinical.
Orbital Rhabdomyosarcoma; Case Report and Review of Literature
Authors:   National Neuroscience Institute, King Fahad Medical City, Riyadh, Saudi Arabia, K Alraddadiu Khulood
Published: May 2023

Background: The wide varieties of rare intraocular and orbital neoplasms differ in presentation in the pediatric population when compared to these same lesions in adults. While most pediatric ophthalmic tumors are benign, they may have a significant impact on vision and may result in significant morbidity and mortality.
Application of Modern Neurosurgical Technologies in Low and Middle-Income Countries
Authors:   Universidad Azteca, Mexico, Zhalmukhamedov Emil
Published: May 2023

In the last 10 years neurosurgical practice has seen exponential growth that has shattered all the imaginary borders of its predecessors. From tremendous advancements in neuroendovascular care to treat stroke patients that have sustained symptoms more than 24 hours ago, to minimally invasive robotic spine surgery that discharges patients’ homes on the same day. All these advancements have drastically improved patient outcomes in the developed world. Many neurosurgical procedures have become more simplified and more intuitive thanks to computer software and hardware that guided neurosurgeons’ decisions in treating patients operatively. However, while all these advancements have proven efficacy and efficiency in the operating room, these technologies are rarely applied or used in low-and-middle-income countries due to a lack of awareness or financial issues. There is the vast majority of newer technologies, that many low and middle-income country hospitals are simply not aware of due to limitations in general awareness or lack of educational materials backing up their efficacy.
A Retrospective Study on the Complications of Ilizarov Technique in the Treatment of Neurogenic Talipes Equinovarus
Authors:   Medical Management Center of Annulus Orthopaedic Hospital Group, Hunan 410000, China, Chen Shouping
Published: May 2023

In order to discuss the postoperative complications of Ilizarov technique in the treatment of neurogenic talipes equinovarus, we conducted a retrospective study on the postoperative complications of neurogenic talipes equinovarus patients treated with Ilizarov technique from January 2013 to December 2020.
The Impact of Preoperative Hemoglobin Concentration and Erythropoietin Administration on Renal Tumors Patients with Inferior Vena Cava Tumor Thrombus Underwent Robot-Assisted Laparoscopic Inferior Vena Cava Thrombectomy
Authors:   The First Medical Center of Chinese PLA General Hospital, 301 Hospital, 28# Fuxing Road, Beijng 100853, China, Wang Deqing
Published: May 2023

Introduction: The impact of preoperative hemoglobin (Hb) concentration and recombinant human erythropoietin (rh-EPO) treatment on renal tumors (RTs) patients with inferior vena cava (IVC) tumor thrombus who underwent robot-assisted laparoscopic inferior vena cava thrombectomy (RAL-IVCTE) were not well studied.
Modular Dual Mobility Cup: A Matched Short-Term Study
Authors:   Section of Orthopaedics and Traumatol- ogy, Ospedale Maggiore di Bologna, Italy, M Ganci
Published: May 2023

Purpose: Instability remains one of the main problems after primary complex and revision hip surgery. The introduction of modular Dual Modular Cup (modular DMC) has helped to overcome some of the limitations of standard DMC. The aim of this study was to review the clinical, radiological outcomes and rate of complications with the use of these kind of constructs.
Direct Anterior Approach Total Hip Arthroplasty for Managing Complicated DDH: Not Just Minimally Invasive in Nature
Authors:   Xinqiao Hospital, Army Medical University, 183 Xinqiao street, Shapingba District, Chongqing 400038, China, Zhang Yuan
Published: May 2023

The aim of this article is to evaluate the article by Zai-yang Liu et al. titled Direct Anterior Approach in Crowe Type III-IV Developmental Dysplasia of the Hip: Surgical Technique and 2 years Follow-up from Southwest China, published in the Orthopaedic Surgery in April 2020 and titled Surgical technique and case series of total hip arthroplasty with the Heuter anterior approach for Crowe type IV dysplasia, published in The Journal of Bone and Joint Surgery in November 2020, by Viamont-Guerra et al. [1,2].
Delayed Wound Healing in Aged Mice is Associated with Traumatic Stress, not with EGFR Block
Authors:   National Center for Laboratory Animal Breeding, Havana, Cuba, Fuentes Dasha
Published: May 2023

Background and Aims: Studies evidenced no wound healing risks related with EGFR blockade but it is unknown whether antiepidermal growth factor receptor therapy poses an additional risk for the wound healing process in aged patients. The objective was to evaluate the effect of EGF block in the wound healing of aged mice.
Clinical and Radiographic Results of a Dual-Component Intramedullary Implant for Hammer Toe Deformity in Patients with Rheumatoid Arthritis
Authors:   Osaka City General Hospital, 2-13-22 Miyakojima hondori, Miyakojima, Osaka 534-0021, Japan, Tada Masahiro
Published: May 2023

Objectives: Clinical and radiographic results of proximal interphalangeal (PIP) joint arthrodesis using a dual-component intramedullary implant for rheumatoid arthritis (RA) forefoot deformities have not been reported. Thus, the outcomes of this implant were investigated.
Exploring the Mechanism of “Fangyifang” in the Prevention of COVID-19 based on Network Pharmacology and Molecular Docking
Authors:   Shandong University of Traditional Chinese Medicine, Jinan, China, Jieqiong Wang , Mingqi Qiao ,   Shandong University of Traditional Chinese Medicine, Jinan, China
Published: May 2023

Objective: To investigate the mechanism of FangyiFang in preventing novel coronavirus pneumonia (COVID-19) using network pharmacology and molecular docking technology. Methods: In accordance with the pharmacopoeia of Traditional Chinese Medicine (TCM), the characteristics and main efficacy of herbal medicine in the FangyiFang were obtained. TCMSP database was searched to obtain the ingredients of herbal medicine.
Enhanced Cardiac Reverse Remodeling after Pulmonary Artery Denervation Combined with Mitral and Maze Surgery
Authors:   Chuvash State University, 15 Moskovskiy Prospekt, 428015 Cheboksary, Russia, NA Trofimov
Published: May 2023

Background: The study evaluates the effectiveness of cardiac reverse remodeling in patients after surgical treatment of high pulmonary hypertension (PH) in patients with mitral valve disease and Atrial Fibrillation (AF).
Research progress of miRNA-326 in malignant tumors
Authors:   Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, No .3 Xincun Street, 030013, Taiyuan, Shanxi, China., L Feng
Published: May 2023

MicroRNAs (miRNAs) are endogenous mediators of RNA interference and have key roles in the regulation of cell and tissue gene expression under a healthy, inflamed, stimulated, carcinogenic, or pathological states. The imbalance between miRNA and genes can cause a series of diseases, including malignancies. The role of miR-326 as a tumor suppressor miRNA in much human cancer confirmed.
Ulcerative colitis and autoimmune hemolytic anemia in adult male patient: A rare case report
Authors:   Palestine Polytechnic University, Hebron, Palestine., Awaysa Asala Mohammad
Published: May 2023

Autoimmune Haemolytic Anemia (AIHA) as a manifestation of Ulcerative Colitis (UC) is a rare occurrence. This case report describes a 21-year-old male patient diagnosed with UC who was treated with medication, but 11 months later developed Coombs-positive AIHA. Although AIHA in UC patients is more commonly observed in females with pancolitis, the exact mechanism behind this phenomenon remains unclear. This case report presents a theory that sheds light on the potential underlying mechanisms.
Initial results of screening program in Mongolia where burdening high gastric cancer
Authors:   Mongolian National University of Medical Sciences, Mongolia., Gantuya Boldbaatar
Published: May 2023

Background: Mongolia is the leading country by the incidence and mortality rate of gastric cancer. In 2022 national cancer screening program for upper gastrointestinal neoplasia was initiated therefore we conducted the multi-center study for determining the gastric cancer among Mongolian population.
Environmental Product Declaration Approaches on the Brazilian Experiences: A Review
Authors: De Brito Maria Alice Leite , Da Silva Elaine Aparecida
Published: May 2023

The Environmental Product Declaration (EPD) is a type of label that has been considered reliable and complete, and it is commonly used in purchasing decisions, product design definition, environmental communication, data sources, and other applications. This article examines the approaches for the development of EPD in the Brazilian context, taking into account the initiatives of interested parties as well as the circumstances for its adoption by national firms. This work adds value by assessing which works in Brazilian literature and experiences focus on EPD, contextualizing the issue, and offering this type of label as a strategic resource. Between 2015 and 2022, the bibliographical survey uncovered 20 works. The Prisma 2020 checklist was utilized to conduct the systematic review, and the analysis in this study was both quantitative and qualitative. Since NBR ISO 14025 (2015), the publications have been consistent. Only 35% of the review content was obtained from journals, with 6 of the 7 publications resulting from academic works from their authors' postgraduate training processes, indicating a concentration of studies by a few scholars, all linked to universities in Brazil's south and southeast. Studies have shown that EPD is a valuable tool for environmental management due to its consistency, reliability, and completeness of data. However, due to a lack of Brazilian experience, this resource is not commonly known, disseminated, or employed. EPD has potential to be used as a strategic resource for businesses due to Brazil's normative, legal, and structural conditions for adoption.
Analytical Investigations of the Mechanotransduction of Mesenchymal Stem Cell for Regulating Cell Fate Decisions
Authors:   Department of Biomedical Engineering, University of Lagos, Akoka, Lagos, Nigeria, Adeleye O. A. , Omotosho-Dare T. ,   Department of Systems Engineering, University of Lagos, Akoka, Lagos, Nigeria, Yinusa A. A. ,   Department of Mechanical Engineering, University of Lagos, Akoka, Lagos, Nigeria
Published: May 2023

Background: The evolution of new biomaterials in tissue engineering is under constant investigation. These biomaterials undergo mechanical stimuli induced cell-differentiation of the mesenchymal stem cell in their transition stage, and the developed dynamic model for this mechanotransduction (mechanical stimuli) process for regulating the fate of the mesenchymal stem cell is a set of coupled nonlinear differential equations whose exact solutions cannot be easily obtained with the common analytical methods. Objective: The analytical investigation of the dynamical model for the mechanotransduction of mesenchymal stem cell for regulating cell fate decisions is presented. Methods: A special analytic technique known as Differential transform method (DTM) was applied to obtain the solutions for the developed dynamic model and was validated with the fourth order Runge-Kutta numerical method (RK4). Results: The obtained analytical solutions have good agreement with the RK4 numerical solutions and past simulated studies. The effects of systems’ large (30k–300k) and low (0k–1.0k) stiffness levels, k 1 and degradation rate of the corresponding gene factor d1 on effective stiffness adhesion area were investigated. At low values of the system’s high stiffness (30k–300k), the effective stiffness adhesion area reduces, and at large stiffness level, the curve becomes asymptotic, but when it is further increased, it has a negligible impact on the effective stiffness adhesion area. It is also observed that at low values of the system’s low stiffness (0k–1.0k), the low stiffness k 1 and degradation rate of the corresponding gene factor d1 shows a negligible impact on the effective stiffness adhesion area at the initial state of response, while an increase in the low stiffness k 1 causes a corresponding increase in effective stiffness adhesion area, but an increase in degradation rate factor d1 causes a decrease in effective stiffness adhesion area. Conclusion: The obtained results from the dynamical analysis can be applied in developing new techniques in controlling the fate of mesenchymal stem cell’s transplantation and designs of new biomaterials.
Antihyperglycaemic and Safety Evaluation of the Combination Effect of Selected Plants in Diabetic Animal Models
Authors:   Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria, Imaga NOA , Babalola O. M. ,   Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria, Ashiru M. A. ,   Department of Chemical Sciences, Biochemistry Unit, College of Natural and Applied Sciences, Fountain University, Osogbo, Osun State, Nigeria, Taiwo O. ,   Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria, Abiru O. ,   Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria, Awodele O. ,   Department of Pharmacology, Toxicology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria
Published: May 2023

Background: Hyperglycemia is a common side effect of untreated diabetes, and it can result in long-term damage to specific body organs. Several herbs including Vernonia amygdalina, Ocimum gratissimum, and Allium sativum have been used to treat hyperglycemia in Nigeria. There has not been any systematic research on the toxicity and efficacy of synergistically combining three plant options. As a result, this study aims to investigate the toxicological profile and anti-hyperglycemic capabilities of the combination of three different medicinal plants in treating Type 2 diabetes. Materials and Methods: Ethanol extract was prepared from the combination of equal proportions of leaves of Vernonia amygdalina, Ocimum gratissimum, and bulbs Allium sativum. Acute and sub-chronic toxicity (90 days) were carried out using standard protocols. Freshly prepared streptozotocin (50 mg per kg body weight) was injected intraperitoneally into rats after an overnight fast. Graded doses of the extract (100, 200, 400, and 800 mg/kg) were administered orally to separate groups alongside 200 mg/kg pretreated and control groups for 21 days. The serum obtained after the sacrifice was evaluated for biochemical, insulin secretion, leptin and antioxidant enzyme assays and a histopathological examination was carried out. Results: Toxicity profile results showed that the combined extract is safe (> 5000 mg/kg) for use. This was corroborated by findings from the biochemical assays. The extract exhibited significant (p > 0.05) anti-hyperglycaemic potential at different doses, especially at 200 mg/kg bw in diabetic rat models. WBC decreased, platelet, MCV increased, liver function enzymes, total bilirubin, urea reduced, HDL increased, antioxidant enzymes, insulin increased and leptin reduced significantly (p > 0.05) respectively. No congestion or atrophy was observed in the histopathological examination. Conclusion: This combined extract formulation is thus suggested as a source of bioactive compounds for targeted use in the development of a new antidiabetic phytomedicine.
Assessment of the Quality of Diclofenac Tablets Marketed in Gombe Metropolis, Nigeria
Authors:   Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Gombe State University, Gombe Nigeria., Okpanachi G.O. , Yahya F. ,   Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Gombe State University, Gombe Nigeria., Bwala J.A. ,   Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Gombe State University, Gombe Nigeria., Maikifi S.A. ,   Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Gombe State University, Gombe Nigeria., Emenike I.V. ,   Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Gombe State University, Gombe Nigeria.
Published: May 2023

Background: Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzyme cyclo-oxygenase and decreases the synthesis of prostaglandins. Diclofenac tablet is one of the commonly used NSAID marketed in Gombe metropolis. Objectives: The study is aimed at assessing the quality of different brands of diclofenac tablets (50 mg) sold at Pharmacies and Patent medicine shops (PMS). Method: Ten diclofenac tablet brands were obtained from registered Pharmacy shops and labelled “A to J” while ten brands from PMS were labelled “K to T”. The quality of the tablets was evaluated using official and non-official parameters such as uniformity of weight; thickness; diameter; crushing strength (CS); friability (FR); disintegration time (DT), wetting time, dissolution testing and tablet content uniformity. Results: Brands A, E, J from Pharmacies and K, N, Q, R from PMS had mean CS within the range of 4-7 kgF. Others had CS > 7 kgF. The FR values of all the brands except F and T were <1.0 %. All the tablet brands except Q disintegrated in <15 min. All the brands obtained from pharmacies and PMS released >75 % of the drug within 30 min except brands G and T. Conclusion: Almost all the brands were of good quality because they passed the prescribed tests. But only a few tablet brands most especially G and T that showed slightly dissimilar results when compared with the BP specifications.
Cauliflower (Brassicae oleracea) extract restores hormonal imbalance, resumes follicular maturation, and down regulates oxidative stress in oestradiol valerate- induced polycystic ovary syndrome in Sprague-Dawley rats
Authors:   Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria, Gbotolorun S.C. , Ogunlade B. ,   Human Anatomy Department, Federal University of Technology, Akure, Nigeria, Oladele O.M. ,   Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria, Sogbesan O.Z. ,   Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria
Published: May 2023

Background: Polycystic ovary syndrome is a common cause of anovulatory infertility. Objectives: This study investigated the ameliorative effect of ethanolic extract of cauliflower in oestradiol valerate-induced polycystic ovary syndrome in Sprague-Dawley rats. Method: Twenty five female rats weighing between 120-160 g were used. They were grouped into five (Groups 1-5; N=5). Polycystic ovary syndrome was induced using oestradiol valerate (16 mg). Groups1and 2 served as negative and positive control respectively, groups 3-5 received cauliflower (200, 500 and 1025 mg/kg body weight) for four weeks. Animals were sacrificed; blood and ovarian tissues were collected for biochemical analysis and histology. Results: The relative weight of the ovary was increased significantly in all the groups compared to the control. This significantly reduced when high dose cauliflower group was compared to EV-group. MDA and SOD levels increased significantly in EV-only groups compared to control. Treatment with cauliflower successfully reduced MDA and SOD levels in comparison to EV-only groups. On the other hand, GSH and catalase did not show any significant differences when the treatment groups were compared to control. FSH and progesterone reduced significantly while LH, testosterone, and oestrogen levels increased significantly in EV-only groups compared to control. Treatment with cauliflower was able to ameliorate these effects. Histological sections showed cystic follicles in EV- only treated group compared to control. Treatment with cauliflower extract in increasing doses was able to rescue growing follicles from cystic formation. Conclusion: Cauliflower extract restores hormonal imbalance, recues follicles from cystic formation, and combats oxidative stress in oestradiol valerate-induced polycystic ovary syndrome in Sprague-Dawley rats.
Rutin and Quercetin Ameliorates Micronutrient Levels in Dextromethorphan- Induced Testicular and Epididymal Toxicity
Authors:   Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idiaraba, Lagos, Nigeria, Adebajo A.O. , Gbotolorun S.C. ,   Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idiaraba, Lagos, Nigeria, Oremosu A.A. ,   Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idiaraba, Lagos, Nigeria
Published: May 2023

Background: Dextromethorphan has been reported to be deleterious in males. Epididymal and testicular micronutrients levels play important roles in male fertility. Objective: To investigate the deleterious effects of dextromethorphan (DM) on epididymal and testicular micronutrients and possible amelioration by rutin and quercetin Materials and Methods: Eighty rats (150 ± 30 g) divided into four groups (N=20; A-D) were used. Group A, control received distilled water (DW); groups B, C and D received 20, 40 and 80 mg/kg of DM respectively. At the end of treatment period for 4 weeks, five animals were selected from each group and sacrificed. Epididymal and testicular micronutrients, and testicular antioxidant activities were analysed. The remaining 15 rats were divided into 3 sub-groups (N=5; E-G). The animals received rutin (25 mg/kg), quercetin (50 mg/kg) and DW respectively for 4 weeks to ascertain recovery rate. The rats were sacrificed and analysed as in previous groups. Results: Significant reduction in micronutrient levels were recorded when DM-groups were compared to control but when recovery-alone group was compared to DM-groups significant increases were observed only in selenium, calcium and vitamin C (testicular fluid) and Vitamin E (epididymal fluid). All micronutrients measured increased significantly when DM and recovery-alone groups were compared to rutin and quercetin groups respectively. An increase in lipid peroxidation and a significant decrease in catalase and superoxide dismutase were observed when DM-groups were compared to control. Conclusion: Deleterious effect of DM on testicular and epididymal micronutrients was ameliorated by supplementation with rutin and quercetin.