bluuebunny/crossref_metadata_2025 huggingface dataset:
Fermentasi kombucha bunga telang (Clitoria ternatea L) sebagai produk bioteknologi sederhana dalam memberikan reaksi farmakodinamik mencit (Mus musculus L) yang terpapar asap rokok dan morfometri ovarium
Authors: Margarisa Dwiyarina , Rezaldi Firman , Pruschia Isti Dwi , Andry Muhammad , Fadillah M. Fariz , Muhardiyanti Mutia , Jaya Hendra , Halimatusyadiah Leni , Nasution Muhammad Amin
Published: October 2023

Indikator kesuburan pada wanita salah satunya adalah kerja ovarium secara fungsional yang optimal. Menurunnya fungsi kerja ovarium secara kualitas dan kuantitas dipengaruhi oleh paparan asap rokok. Komponen utama yang terkandung pada asap rokok meliputi tar, nikotin, karbon monoksida, gas anorganik, logam berat, nitrosamine, karbonil, formaldehida, dan hidrokarbon aromatik polinuklir. Komponen-komponen utama yang terkandung pada asap rokok tersebut berkolerasi secara positif dalam mempengaruhi kadar hormon reproduksi wanita bahkan menurunkan fertilitas. Salah satu upaya dalam mencegah radikal bebas asap rokok dan berpotensi sebagai antioksidan secara natural adalah mengkonsumsi kombucha bunga telang. Kombucha bunga telang dari penelitian sebelumnya mengandung fitokimia yang mampu menghambat radikal bebas. Tujuan dari penelitian ini adalah untuk mempelajari mengenai pengaruh kombucha bunga telang terhadap morfometri ovarium mencit betina yang terpapar asap rokok. Desain penelitian ini adalah Rancangan Acak Lengkap (RAL). Hewan uji yang digunakan berupa mencit betina yang berumur 10 sampai 12 minggu yang berbobot 20 sampai 20 g sejumlah 24 ekor. Kombucha bunga telang yang diberikan adalah 10 mL/L , 20 mL/L , 30 mL/L , dan 40 mL/L. Pemaparan asap rokok terhadap mencit dilakukan pada hari 1-20 sebanyak 1 batang dan diobati dengan kombucha bunga telang pada hari ke 21-40 hari. Pengawinan mencit betina dilakukan pada hari ke 40. Pengamatan morfometri ovarium seperti panjang, lebar, bobot, dan jumlah korpus luteum dilakukan pada 18 hari usia kebuntingan. ANOVA dan DMRT dengan taraf kepercayaan 1% adalah analisis data yang dilakukan. Kesimpulan dalam penelitian ini adalah kombucha bunga telang mempunyai efek yang baik dalam memperbaiki taraf fertilitas yang dapat diamati dengan parameter uji seperti panjang, lebar, bobot, dan jumlah korpus luteum serta pemberian kombucha dengan konsentrasi 40 mL/L merupakan perlakuan yang terbaik.
Response of Pigment Epithelial Detachment to Three-Loading-Dose of Intravitreal Anti-Vascular Endothelial Growth Factor in Neovascular Age-Related Macular Degeneration
Authors: SARİYEVA ISMAYİLOV Ayna , ERSEVEN Cansu , KOYUNCU Kevser , ULUSOY Mahmut Oğuz
Published: October 2023

Objective: Response of pigment epithelial detachment (PED) to three loading dose of intravitreal bevacizumab (IVB) treatment in neovascular age-related macular degeneration (nAMD) cases.

Methods: OCT findings (PED height (µm), diameter(µm) and area (mm²), central macular thickness (CMT), central choroidal thickness (CCT), intraretinal fluid (IRF), subretinal fluid (SRF)), and morphological features of macular neovascularization (MNV) in OCTA before and after three loading doses of IVB were examined and compared.

Results: Forty-two eyes of 42 naive nAMD patients with PED were included. Fifteen patients had serous and 27 patients had fibrovascular PED. After three loading doses, best corrected visual acuity (BCVA) (in Snellen) increased from 0.22±0.19 to 0.29±0.22 (p
A Hybrid Approach for Data Hiding using Twofish Algorithm and Compression Steganography Techniques
Authors: Merlin K  , Pradiksha S  , Deepa Lakshimi B  , Ramya G
Published: October 2023

Data compression and encryption are essential components of information security, facilitating efficient data handling, reduced storage requirements, and secure data transmission. The system presents a novel hybrid data compression algorithm that combines lossy and lossless compression techniques, along with Twofish cryptography. The hybrid approach leverages the strengths of different compression techniques. First, the Huffman coding algorithm is employed to compress textual data efficiently. Subsequently, the cover image undergoes lossy compression using the Discrete Wavelet Transform (DWT) technique. To fortify data security, the Twofish algorithm offers robust and high-level encryption. The encrypted data is then embedded into the compacted cover image using the least significant bit (LSB) technique in a steganographic manner. In the evaluation phase, the system's performance is assessed using key metrics, bits per pixel, mean squared error (MSE), peak signal-to-noise ratio (PSNR), and structural similarity index (SSIM). Comparative analysis with existing methodologies demonstrates the superior performance and methodological efficiency of the system. The results indicate that the hybrid approach strikes a balance between compression efficiency and data security, enabling faster data transmission over limited bandwidth connections and effectively utilizing storage media.
Tetralogia de Fallot e suas Implicações em Odontologia
Authors: Santos Gislene Rodrigues dos , Silveira Millena Luiza Vaz da , Sommer Antônio Afonso
Published: October 2023

A Tetralogia de Fallot (TF) é a cardiopatia congênita cianótica mais frequente. Como sugere o nome, consiste em quatro alterações no coração, sendo elas a existência de um defeito ou comunicação no septo ventricular, a raiz da aorta sobreposta ao defeito septal ventricular ou em dextroposição, a estenose da artéria pulmonar e a hipertrofia do ventrículo direito. Existe, portanto, um grau de obstrução do fluxo sanguíneo comprometedor do transporte de oxigênio no organismo. O propósito deste trabalho foi realizar uma reisão de literatura narrativa, qualitativa, em que se buscou, nas bases de dados PubMed, SciELO e Google Acadêmico, trabalhos científicos versando sobre a TF e sua relação com a odontologia, publicados nos últimos dez anos. A prevalência de TF é de 3 a cada 10.000 nascimentos, representando 10% de todas as malformações congênitas cardíacas, sendo mais frequente no gênero masculino, e a etiologia é multifatorial, mas não bem esclarecida. Os principais sinais clinicos são hipóxia e cianose. No sistema estomatognático, o desenvolvimento dentário e o crescimento ósseo são afetados, além dos tecidos moles. As principais manifestações são agenesias, hipoplasias do esmalte e atraso na erupção dentária e mucosas cianóticas. Diagnóstico correto, minucioso e rápido é fundamental para um tratamento sem complicações e um bom prognostico. Os exames necessários para detectar a enfermidade são eletrocardiograma e ecocardiografia fetal no pré-parto e no pós-parto, sendo possível observar a comunicação interventricular e repercussões associadas. O tratamento consiste na intervenção cirúrgica, muito precocemente. Crianças com TF devem iniciar as visitas ao consultório odontológico já nos primeiros anos de vida, e adequações do cirurgião-dentista para o atendimento desses pacientes precisam ser adotadas sempre visando prevenção de procedimentos mais invasivos. O cirurgião-dentista tem importante papel na equipe multidisciplinar envolvida com TF, no intuito de realizar a promoção e prevenção da saúde bucal, controlando a ocorrência dos problemas bucais relacionados e seu agravo com comprometimento sistêmico.
Cirurgia de Vesícula Biliar: Colecistectomia Laparoscópica: Uma análise da colecistectomia laparoscópica como abordagem preferencial para a remoção da vesícula biliar em pacientes com cálculos biliares.
Authors: Tanuri Filipe Duarte , Medrado Matheus Remy Sardinha , Santos Luiz Guilherme Sastre dos , Rodrigues Carolina Sastre , Calil Juliana Vasconcelos , Rego Myrella Zágna Leite do
Published: October 2023

A cirurgia de vesícula biliar, particularmente a colecistectomia, é um procedimento essencial no tratamento de cálculos biliares. Este artigo de revisão analisou a colecistectomia laparoscópica como a abordagem preferencial para a remoção da vesícula biliar em pacientes com cálculos biliares, considerando sua eficácia, comparação com outras técnicas cirúrgicas e considerações na população geriátrica. A colecistectomia laparoscópica demonstrou consistentemente sua eficácia, resultando em menor tempo de recuperação, dor pós-operatória reduzida e menor incidência de complicações em comparação com a colecistectomia aberta. A preferência pela abordagem laparoscópica é respaldada por evidências sólidas, embora a escolha da técnica cirúrgica deva ser personalizada, considerando a complexidade dos cálculos e as condições clínicas do paciente. A comparação com outras abordagens cirúrgicas, como a colecistectomia aberta e a litotripsia extracorpórea por ondas de choque (LEOC), destacou as vantagens da colecistectomia laparoscópica, incluindo menor tempo de internação e recuperação mais rápida. No entanto, a seleção da técnica cirúrgica deve ser cuidadosamente avaliada de acordo com o caso. Na população geriátrica, avaliar a fragilidade e as comorbidades é crucial antes da cirurgia. Embora os idosos possam apresentar desafios adicionais, a colecistectomia laparoscópica permanece como uma opção segura e eficaz, desde que os riscos sejam gerenciados adequadamente. Em resumo, a colecistectomia laparoscópica é a abordagem preferencial para a remoção da vesícula biliar em pacientes com cálculos biliares devido à sua eficácia e recuperação mais rápida. No entanto, a decisão cirúrgica deve ser individualizada, levando em consideração as complexidades clínicas e as preferências do paciente.
MEDICALIZAÇÃO DA MORTE NO BRASIL: impactos e repercussões do consumo farmacológico sob a ótica do cuidado paliativo
Authors: Neves Felippe Gomes de Oliveira , Paula Enimar de , Monteiro Heitor Campos , Braga Christiane Lourenço , Santos Isabela Carvalho Dos , Almeida Yzabelle Ribeiro de , Silva Ary Carlos Spacoski da , Ribeiro Wanderson Alves , Fassarella Bruna Porath Azevedo , Neves Keila do Carmo
Published: October 2023

Introdução: Como a medicalização da morte entrou no cuidado paliativo e na vida do individuo como um todo, de seus familiares e de toda sua coletividade. Abrindo um novo olhar e um novo modo do cuidado.

Objetivo: entender como o cuidado paliativo inseriu a medicalização da morte em seu processo histórico, podendo assim modificar seus cenários e  toda abordagem do processo de transformação do cuidado, ocorrido a partir da secularização. Visto como a perda da sagacidade e leigo, a categoria da  expectativa de conhecer torna-se objeto de medicalização, adquirindo novos significados. Analise e discussão dos resultados:: Pode se dizer que a medicalização é um algo que tem se desde os séculos passados ate hoje, para todas as fases da vida. Colocando como um problema do processo de medicalização que não é recente, a medicalização já era inclusa na sociedade, sendo incluída no cuidado paliativo como relação à saúde e a construção de uma morte com dignidade, sendo que acalçaram o processo de desmedicalização da morte. Metodologia:tipo de revisão de artigo, haja vista que utilizou como base fontes secundarias para composição do artigo.Usamos como instrumento de coleta de dados por revisão bibliográficas. Com medicalização em ênfase no cuidado paliativo. Nesse passo utilizamos a abordagem qualitativa. Dessa froma pretende analisar pesquisas bibliográficas.

Conclusão: Sempre houve a medicalização ao longo dos séculos, mas se consolidou a partir do momento em que falamos de medicalização ao nos referir que algo se tornou médico, portanto alvo de um olhar clínico, que analisa, diagnostica e prescreve formas de tratar o problema, conhecido como hospitalocêntrico na atenção a saúde. O cuidado paliativo entrou como uma forma de ver a morte de modo diferente, não a ver como o fim e sim de encarar a morte com novos olhares em frente a um grande processo para a morte, assim observando um propósito melhor a qualidade de vida do individuo e suas possíveis possibilidades, sempre valorizando a sua vontade, como dito, no destaque recebido ao direito de autonomia individual, o que denota a preeminência de valores morais vigentes em cada contexto examinado. Pode até se dizer que o cuidado paliativo é o promotor da desmedicalização da morte.
CHEMICAL AND PHYSICAL METHODS OF CHOCOLATE PROCESSING: ADMINISTRATION PROCESS
Authors:   Pavlo Tychyna Uman State Pedagogical University, Zadorozhna Olena
Published: October 2023

From the harvesting of the cocoa beans to the formulation of the final chocolate product many complex changes occur. The properties and behavior of the fat and the dramatic change in flow characteristics are most notable. The purpose of the work is to clarify the relationship between the types, composition, methods of preparation and consumption of chocolate and its impact on human health. In order to achieve the goal, we set the following work tasks: to get acquainted with the history of the origin of chocolate; to investigate the indicators of chocolate quality; evaluate informational, quantitative characteristics of chocolate; to determine the effect of chocolate on the human body, to conduct qualitative reactions to individual chemical substances included in the composition of chocolate. These changes occur in part during the refining process which includes roasting, winnowing, grinding and conching. Most notable in influencing the product is conching which is the agitation of chocolate coupled with aeration and heat. This treatment is a time and energy consuming process but has a remarkable mellowing effect on the flavor and promotes a decrease in viscosity of the final product. The escape of undesirable volatiles derived from oxidative and carbonyl reactions catalyzed by heat and aeration have been implicated. Research methods: study of literary and electronic media, generalization of the material found, sociological survey, chemical experiment, analysis of the obtained results. The physical effects brought about during conching encompass more than a simple mixing. Included, in addition to the chemico-physical aspects of conching itself, are the aspects of the cocoa bean, fermentation and roasting which may influence the product The scientific novelty of the obtained results: qualitative reactions were carried out on individual chemical substances included in the composition of chocolate. The methodological basis of the research is fundamental principles of the system approach, relevant aspects of market and technical research and state regulation of chocolate products studied with application economic-statistical and physico-chemical methods. It is used in the work the following methods of the developed product: statistical, organoleptic, method determination of protein content in the finished product, method of determining the indicator glycemic The composition of chocolate was theoretically investigated. In the perspective of further research, we plan to expand the assortment of porous chocolate due to the creation of new flavors (Ex. porous chocolate with caramel flavor, fruit flavors based on white chocolate mass).
PSYCHOLOGICAL WELL-BEING AND STRATEGY TO COUNTER PROFESSIONAL BURNOUT AMONG LAW ENFORCEMENT OFFICERS
Authors:   Zhytomyr Polytechnic State University, Burlakova Iryna , Melnychuk Dmytro ,   Zhytomyr Polytechnic State University, Oksiutovych Maryna ,   Zhytomyr Polytechnic State University, Nikolaienko Serhii ,   Zhytomyr Polytechnic State University
Published: October 2023

The psychological health of law enforcement officers has always been of primary importance. During the performance of official duties, law enforcement officers often face long-term trauma, stress and emotional overload, which can impair their psychological well-being and lead to professional burnout. The purpose of the study is to analyze the psychological well-being and strategies for combating professional burnout of law enforcement officers in order to develop recommendations for improving their mental state and improving the quality of work. The research was conducted by surveying employees of law enforcement agencies during a week (July 2023) using a Google form. The 111 people took part in the survey, including 66.7% of men (74 people) and 33.3% of women (37 people). The article deals with psychological training developed specifically for employees of law enforcement agencies with the aim of ensuring their psychological health and providing self-help tools. This training is aimed at helping employees in solving their psychological needs in the conditions of long-term traumatization and stressful service environment. The effectiveness of training on the psychological well-being of employees of law enforcement agencies is being investigated. According to the results of the survey after the training, more than 80% of the participants noted an improvement in their psychological state and a decrease in the level of stress. Analysis of the results provides important recommendations for supporting law enforcement officers and improving their psychological well-being. Ensuring psychological well-being and combating professional burnout is becoming an urgent task that requires attention and action from both the employees and the management and state bodies to ensure the quality and efficiency of the work of law enforcement agencies. The survey found that workers face significant levels of stress and burnout due to the complexity of their jobs. The need for psychological support and stress management tools is essential. Building psychological well-being includes developing strategies that include self-esteem, psychological support, and other ways to manage stress. Summing up, the conducted survey and training indicate the need to overcome the problem of professional burnout and improve the psychological well-being of law enforcement officers through the development and implementation of special strategies and psychological support programs.
CONHECIMENTO DO USO DE CIGARROS ELETRÔNICOS POR ACADÊMICOS DO CURSO DE ODONTOLOGIA
Authors: Carvalho Emelly de Souza de , Pinto Ana Júlia Ferreira , Paulo Alana Cândido , Santana Euzamar de Araújo Silva , Ribeiro Michael Ranniery Garcia , Diniz Ana Carolina Soares Diniz Soares , Ribeiro Yuri Jivago Silva , Carvalho Marcio Santos de
Published: October 2023

Introdução: Há uma crescente discussão se os efeitos do uso dos cigarros eletrônicos são os mesmos do tabagismo, considerando-se causa de doenças crônicas não transmissíveis Objetivo: realizar uma revisão integrativa da literatura sobre a autopercepção do uso de Cigarros Eletrônicos (CEs) entre acadêmicos de odontologia de diferentes países no mundo. Métodos: O presente trabalho corresponde a uma revisão da literatura do tipo integrativa, que teve como intuito revisar a literatura atual disposta na bases de dados Scientifique Eletronic Library Online (SCIELO), Literatura Latino-Americano e do Caribe em Ciências da Saúde (LILACS), US National Library of Medicine (PUBMED), e WEB OF SCIENCE (Clarivate Analytics) que tratasse do tema de escolha, usando descritores preestabelecidos, inclusos apenas artigos dos últimos 6 anos, disponíveis na integra e excluídos aqueles que se distanciavam do tema proposto. Resultados: A amostra final desta revisão foi constituída por 8 artigos científicos, selecionados pelos critérios de inclusão previamente estabelecido Conclusão: Os estudantes de odontologia não apresentaram conhecimento assertivo acerca do cigarro eletrônico e suas consequências na saúde bucal.
Diferencias generacionales en el comportamiento del consumidor en línea en la ciudad de Aguascalientes
Authors: Pastrana Castillo Priscila Gabriela , Bojórquez Guerrero Lorena Patricia , Robles Casillas Fernando
Published: October 2023

El objetivo de este estudio cuantitativo fue describir el comportamiento del consumidor en línea, centrándose en la comparación de tres grupos generacionales: Baby Boomers, X y Millennials. La investigación se realizó en la ciudad de Aguascalientes, México. Es crucial que las MiPymes conozcan el comportamiento de compra entre generaciones con el fin de encausar sus campañas publicitarias, estrategias de venta y creación de canales de venta en línea a nichos de mercado generacionales. Para recopilar los datos, se utilizó un cuestionario estructurado dividido en dos secciones; el primero para identificar el perfil del respondiente y el segundo para determinar el comportamiento del consumidor en línea bajo las dimensiones de hábitos de compra,  motivador de compra, plataforma de compra, producto comprado, intención de compra y satisfacción del consumidor. La muestra consistió en 384 participantes, de los cuales 166 no realizaron compras en línea. Los 218 restantes fueron considerados sujetos válidos para medir el comportamiento del consumidor en línea debido a que realizaron al menos una compra bajo esta modalidad. Los resultados constatan que las tres generaciones buscan fechas especiales y sitios nacionales a la hora de comprar. Los Millennials utilizan más este canal debido a que entienden mejor el entorno digital, cada generación tuvo contacto con el mundo tecnológico en diversas etapas de su vida.
Influence of the immunomodulator kargdekhin on cellular and humoral immunity of the holstein-frisian and red-steppe breed of cattle in leptospirosis
Authors:   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Koshchaev Andrey G. , Gugushvili Vladimir M. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia
Published: October 2023

Regardless of the breed affiliation in cattle with leptospirosis, suppression of neutrophil activity to the ability to digest foreign agents, neutrophil mobilization coefficient and, conversely, an increase in phagocytic number were revealed. Phagocytosis indices in the Red Steppe breed were significantly higher than in the Holstein-Frisian breed. In patients with leptospirosis of the Holstein-Frisian breed, suppression of the activity of acid phosphatase, myeloperoxidase, and the level of lysosomal cationic proteins was revealed. The Red Steppe breed showed a decrease only in the activity of acid phosphatase, relative to clinically healthy animals. After the application of highly effective drugs to sick animals (antibiotic, hepatoprotector, vitamins, trace elements, immunomodulator kargdechin), an increase in phagocytosis processes was found, in addition, cytochemical parameters were restored faster in the Red Steppe breed, which indicated a higher immune status relative to the Holstein-Frisian and breed.
Analysis of laboratory diagnostics of chlamydia in animals and birds in the Russian Federation for 2019–2021
Authors:   Testing Central Scientific and Methodological Veterinary Laboratory Federal Center for Animal Health, Moscow, Russia, Zyuzgina Svetlana V. , Zinovieva Olga E. ,   Testing Central Scientific and Methodological Veterinary Laboratory Federal Center for Animal Health, Moscow, Russia, Lobova Tatyana P. ,   Testing Central Scientific and Methodological Veterinary Laboratory Federal Center for Animal Health, Moscow, Russia, Mikhailova Vera V. ,   Testing Central Scientific and Methodological Veterinary Laboratory Federal Center for Animal Health, Moscow, Russia, Shishkina Maria S. ,   Testing Central Scientific and Methodological Veterinary Laboratory Federal Center for Animal Health, Moscow, Russia, Skvortsova Anastasia N. ,   Testing Central Scientific and Methodological Veterinary Laboratory Federal Center for Animal Health, Moscow, Russia
Published: October 2023

Chlamydia infection causes significant economic damage to various branches of animal husbandry and poultry farming. In the system of veterinary and sanitary measures, it is important to detect the pathogen as early and reliably as possible in various forms of the disease. For this purpose, a number of laboratory methods of direct and indirect diagnosis of chlamydia have been developed over the past years. The article analyzes the results of laboratory tests for chlamydia in state veterinary laboratories for 2019–2021, as well as cases of positive results in the study of biological and pathological materials from animals, including birds. During the analyzed period, 2 750 726 samples of material from animals, including birds, were received by state veterinary laboratories for research on chlamydia, of which 2 645 605 (96,7 %) samples were examined by serological methods, specific antibodies were detected in 0,4 % of blood serum from animals (except birds). Positive results of serological tests require mandatory confirmation by methods of direct detection of chlamydia, their antigens, nucleic acids in biological material. The genetic material of chlamydia during polymerase chain reaction studies was detected in 1 % of samples of biological and pathological material from animals, including birds.
Unification of classification groups of vaccines
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Pimenov Nikolay V. , Kapustin Andrey V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Roenko Andrey D. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2023

Vaccines – immunobiodrugs, for active immunization of people and animals for preventive and therapeutic purposes, today have received a multi-vector and complex development of technology and structure. At the moment, in the world and in the Russian Federation, in particular, there is no single, generally recognized classification of vaccines that combines all modern achievements in vaccinology. The literature uses disparate approaches to classification, naming of vaccines, as well as incomplete reduction of classification groups. In the presented work, an analysis of existing classifications was carried out, their improvement based on new knowledge in the field of vaccine preparations, the creation of new drugs based on genetic engineering, the systematization of scientific information in the field of development of immunobiological preparations and open prototypes. This classification is proposed to be used to create a unified classification of vaccines on the territory of the Russian Federation and the member countries of the Eurasian Economic Union and use it to standardize finished products, educational and methodological publications, scientific reaserches and other theoretical materials. The paper presents four classification groups, each of which is composed in such a way that, if necessary, for example, in the event of the emergence of fundamentally new technologies for the production of vaccines, they can be implemented into it without compromising the overall systematics.
Effect of microalgae feeding to lactating cows on milk quality and milk production
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Bykov Dmitry V. , Vasiliev Alexei A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Syrovatsky Maxim V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2023

In the conditions of a dairy commercial enterprise, a scientific and economic experiment was carried out on two groups of cows – analogues. The duration of the experiment was 104 days. In a scientific and economic experiment, we studied the effect of feeding a suspension of chlorella in the first phase of lactation in the diets of freshly calved lactating cows and cows 2–3 lactations per amount of milk fat and protein in milk. The analysis of average values according to the dynamics of changes in the content of milk fat was carried out. Data were obtained on the positive effect of chlorella suspension on the quality indicators of fat and protein in the milk of cows of the experimental group.
Determination of the residual content of tetracycline in animal products and feed by enzyme immunoassay using a test system Ingvar InTETRA
Authors:   Biotechnological University, Moscow, Russia, Satyukova Ludmila P. , Dorozhkin Vasily I. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology (VNIIVSGE) – branch of the Federal Scientific Center “All-Russian Research Institute of Experimental Veterinary named after K. I. Scriabin and Ya. R. Kovalenko” of the Russian Academy of Sciences, Moscow, Russia
Published: October 2023

In this article, a comparative analysis of the methods used in the territory of the Russian Federation for the determination of tetracycline by enzyme immunoassay was carried out. The results of the experiment on testing the Ingvar test system (Russia) are also presented InTETRA for the determination of tetracycline in animal products and feed by enzyme immunoassay (ELISA). The results were confirmed by high-performance liquid chromatography with a mass spectrometric detector (HPLC MS/MS).
Etiotropic activity of the combined drug «EshriPhage» in vitro
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Pimenov Nikolay V. , Laishevtsev Alexey I. ,   Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences, Moscow, Russia
Published: October 2023

The intensification of the production of livestock and poultry products determines the strengthening of biological control and containment of the morbidity of animals, including birds, as well as the spread of infections that determine sanitary and epizootic distress. Coli-salmonella infection is widespread. By their antibiotic resistance, the microorganisms Escherichia coli and Salmonella spp. they belong to a high and critical priority group, most of the existing antibiotics for which are not active. To implement the tasks facing veterinary science and practice, formed by the global problem of combating epizootics of escherichiosis and salmonellosis, ensuring sanitary well-being, including products, a drug based on bacteriophages «EshriPhage» has been developed. Commission tests of the etiotropic activity of the combined agent «EshriPhage» in vitro in the spot test revealed a high level of epizootically significant isolates of coli-salmonella infection. Data are presented that allow us to recommend the widespread introduction of EshriPhage into practice and the further development of methods of epizootic control over bacterioses using bacteriophages.
Prevalence of acute intestinal infections in calves and pigs in the Krasnodar region
Authors:   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Koshchaev Andrey G. , Chernykh Oleg Yu. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Tishchenko Alexander S. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Manakova Alina Yu. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Yakovenko Pavel P. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Alferov Dmitry O. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia
Published: October 2023

The scientific article presents statistical data on the results of laboratory studies for the presence of pathogenic microorganisms – causative agents of acute intestinal infections among young cattle and pigs in the Krasnodar Territory in the period from 2008 to 2022. The materials used to write the article were provided by GBU «Kropotkin Regional Veterinary Laboratory». In our work, the most frequently reported intestinal diseases of calves and piglets were highlighted, including escherichiosis, enterococcosis, staphylococcosis, streptococcosis, anaerobic enterotoxemia, citrobacteriosis, pseudomoniasis and edematous disease of piglets. A brief description of the pathogens was also given, the most common types of pathogenic bacteria were mentioned. Based on the available data, the frequency of occurrence of acute intestinal diseases was calculated, the percentage of registration of the most common pathogens of infections was established. It has been established that one of the most common acute intestinal pathologies among young cattle and pigs in the Krasnodar Territory over the past 15 years is escherichiosis. Pathogenic E. coli in pathological material was isolated in 41 % of cases in calves, and in 47 % in piglets. Enterococcal infection accounted for 43,3 % of studies in calves and 28,3 % in piglets. Pseudomoniasis, anaerobic enterotoxemia in calves, as well as edematous disease, staphylococcosis and citrobacteriosis in piglets have not been massively registered recently, but are manifested by sporadic outbreaks. Taking into account the current epizootic situation in the Krasnodar Territory for acute intestinal diseases in calves and piglets, it is necessary to conduct regular monitoring of them among the livestock, maintain the veterinary and sanitary condition of livestock farms at the proper level and seek effective, safe and environmentally friendly methods of controlling pathogens.
Endolysins are a promising method of combating antibiotic–resistant microorganisms
Authors:   All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko” of the Russian Academy of Sciences, Moscow, Russia, Laishevtsev Alexey I. , Shastin Pavel N. ,   All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko” of the Russian Academy of Sciences, Moscow, Russia, Supova Anastasia V. ,   All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko” of the Russian Academy of Sciences, Moscow, Russia, Savinov Vasily A. ,   All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko” of the Russian Academy of Sciences, Moscow, Russia, Ezhova Ekaterina G. ,   All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko” of the Russian Academy of Sciences, Moscow, Russia
Published: October 2023

The article reveals one of the promising methods of combating antimicrobial resistance in agriculture, medicine, food industry and other fields – endolysins (enzymes of bacteriophages). The history of the origin, discovery, and production of endolysins is displayed. The mechanism of action of endolysins is shown – destruction of the peptidoglycan layer at the end of the lytic cycle of phage reproduction. The results of endolysin studies in recent years have been searched using the Internet resources Scopus, Web of science, Elibrary, Pub Med and others. Analysis of the literature showed that endolysins are divided into 5 groups depending on the cleavable installation in the peptidoglycan – acetylmuramidase, transglycosidase, glucosaminidase, amidase, endopeptidase. The introduction of endolysins is important - intravenous, intraperitoneal, transnasal, transnasal, vaginal. To date, endolysins effective against such pathogens as Staphylococcus aureus, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterococcus faecalis, Streptococcus suis, Streptococcus equi, Clostridium perfringens, Bacillus anthracis and a number of other pathogens have been studied. Thus, the analysis shows that endolysins can be effective tools in the fight against infectious diseases of animals and safe to use.
Investigating of the Reasons for the Collapse on the Entrance Arches of the Harran Grand Mosque (Ulu Cami) During the Kahramanmaraş Earthquakes (Mw 7.7 and Mw 7.6)
Authors: Nasery Mohammad Manzoor
Published: October 2023

Although historical masonry structures are highly aesthetic, they harbor numerous structural uncertainties. These structures encompass information such as the date of construction, construction methods, material properties, design details and more. They possess diverse identities in various aspects, making the structural assessment of historical buildings a challenging task. Consequently, all historical buildings should be treated with special consideration, and suitable solutions must be devised. In this study, the structural damage causes of the entrance gate of the Harran Grand Mosque (Ulu Cami), which had undergone recent restoration but suffered damage once again during the Kahramanmaraş earthquakes on 6 February 2023 have been investigated. A three-dimensional finite element model of the structure was developed using Abaqus software. In the numerical studies the static as well as non-linear dynamic earthquake analyses were conducted to evaluate the reasons of the collapse of the structure. The structure was subjected to earthquakes from different directions and its compatibility with actual damage scenarios was observed. The study results are presented with contour diagrams of displacement, stress and damage situations. Upon reviewing the numerical findings obtained from the study, it is evident that the actual damage condition of the structure can be reasonably simulated. As a result, it is thought that the earthquake hit the entrance arches from out of plane which caused the collapse. To sum up, by evaluating the damage conditions resulting from such numerical studies, restoration applications can be handled more effectively, ensuring that correct interventions are carried out.
Outcomes comparison between nsaid and placebo in the occurrence of heterotopic ossification after hip surgery: a systematic review
Authors: Aryanugraha Putu Teguh , Aryana I Gusti Ngurah Wien , Sutheno Andrew , Dimitri Dominicus , Lazio Frans
Published: October 2023

Introduction: Heterotropic Ossification (HO) is a devastating condition felt by patients and surgeons. It was caused by inflammatory response triggered by injury through various processes. NSAID is thought to have a capability to limit the process, hence preventing the condition.

Materials and Methods: Various database has been used to search for literatures included in this review. Screening and evaluation were conducted for researches.

Results: Seven studies are included in this review and a table has been formed to show the comparison of HO and Control.

Discussion : This study aimed to assess the occurrence of heterotopic ossification (HO) after hip arthroscopy and compare outcomes between those who received prophylactic nonsteroidal anti-inflammatory drugs (NSAIDs) and those who did not. The hypothesis was that NSAIDs could reduce postoperative HO. The significance of this trend varied in retrospective research due to differences in NSAID regimens. The usefulness of NSAID prophylaxis should be carefully weighed against potential side effects, and patient compliance should be assessed in future research, as it was inconsistently reported in the existing literature.

Conclusion: NSAID lower the rate of postoperative HO, however, more studies need to be conducted to analyze certain efficacy of certain type of HO
As contribuições da Etnomatemática na formação continuada de professores que ensinam matemática
Authors: Dall'Agnol Luzitânia , Santos Maria José Costa dos
Published: October 2023

No século XX, na década de 1970, surge a Etnomatemática visando uma contribuição para melhorias no ensino da matemática, a partir de práticas em diferentes contextos culturais. Ela emerge como um programa promissora que reconhece e valoriza o conhecimento matemático presente nas diversas culturas e práticas sociais de grupos étnicos. Objetiva-se discutir a importância da Etnomatemática na formação continuada de professores que ensinam matemática por meio de uma abordagem intercultural, promovendo uma educação mais inclusiva, significativa e contextualizada em diferentes culturas. Trata-se de um estudo teórico Este estudo apoia-se nas referências de teóricos da formação continuada, e da Etnomatemática. Destaca-se o resultado de duas pesquisas de mestrado que acompanharam o trabalho pedagógico de professores, uma de uma instituição pública Federal (2007) e outra privada (2015), respectivamente, nas cidades de Belo Horizonte (MG) e Lajeado (RS). Conclui-se após análises que os sujeitos das pesquisas, concordaram com a importância de ensinar matemática sob a perspectiva Etnomatemática e suas implicações no contexto social.
A survey of instructional experience of faculty in teacher preparation programs during the COVID-19 pandemic
Authors: Quinn Robert , Waddell, Jr. Glenn
Published: October 2023

“In the spring of 2020, educational professionals rushed to suddenly and unexpectedly shift to remote teaching in light of the COVID-19 pandemic” (Boltz, Yadav, Dillman & Robertson, 2021). During this time, “Schools and universities had to quickly adapt to a distance learning model….” (Stevens, Stevens, & Grady, 2021) as “…professors everywhere scrambled to implement some version of their class in an online format” (Baker & Dannatt, 2020). This study provides an analysis of self-reported survey data gathered from college instructors tasked with preparing preservice teachers or developing in-service teachers, who were forced to transition to online delivery of their courses.
Wireless Sensor Network Based Gas Monitoring System Utilizing ZigBee Technology
Authors: Coboi Alberto , Nguyen Minh T. , La Kien T. , Vu Thang C.
Published: October 2023

This paper presents a ZigBee-based wireless network gas monitoring system, utilizing ZigBee technology to enable reliable and low-cost communication. The system leverages small sensor nodes and ZigBee protocols to collect data on physical phenomena, particularly gas levels, in various environments. The network's low-power consumption and extended range capabilities allow for effective gas sensing within a radius of up to 300 meters. While interoperability with devices from different manufacturers remains a limitation, the system showcases the versatility of ZigBee technology in diverse fields. The study evaluates the system's performance through simulation and experimentation, addresses potential challenges, and proposes future developments to enhance ZigBee-based wireless network gas monitoring systems, offering improved remote monitoring and manipulation capabilities. Furthermore, our research contributes to the advancement of wireless sensor network technology by demonstrating the practicality of ZigBee in gas monitoring. The findings from our experiments and simulations provide valuable insights into the optimization of such systems, which can have far-reaching impacts on environmental monitoring, safety, and industrial processes. In addition, our proposed enhancements pave the way for more reliable and efficient remote monitoring and control, offering substantial benefits for various industries, including environmental management, industrial automation, and beyond.
BUDAYA ORGANISASI DALAM MENINGKATKAN PROFESIONALISME PEMBELAJARAN GURU DI SEKOLAH
Authors: Wahyuni Rina , Limin Dagai L. , Eshariyani  , Savitri Amellya Maretta , Mentarini Nur
Published: October 2023

The aim of this research is to describe organizational culture in improving the professionalism of teacher learning in schools. The approach used in this research is qualitative, with a case study research design. The selection of informants was carried out using purposive sampling and snowball sampling. Research data collection procedures were carried out by observation, interviews and documentation. After the data is collected, analysis is then carried out using an interactive pattern which includes: data condensation, data presentation and drawing conclusions. The research results obtained have shown that organizational culture in improving the professionalism of teacher learning in schools is good by implementing: (a) a culture of discipline for teachers and students; (b) a culture of technological literacy and strengthening teachers' abilities through supervision of learning and providing follow-up through in-house training as an effort to develop the competence and learning capacity of teachers in schools. Apart from that, challenges in increasing the professionalism of teacher learning in schools include: (a) limited ability of teachers to adapt to current curriculum updates; (b) lack of teacher enthusiasm and commitment, especially for teachers who are approaching retirement (after service); and (c) there are still teachers who maintain the habit of using learning methods using lecture techniques throughout the lesson.
SUPERVISI AKADEMIK OLEH KEPALA SEKOLAH UNTUK MENINGKATKAN KOMPETENSI GURU KELAS ANAK BERKEBUTUHAN KHUSUS
Authors: Sumarnie  , Ernawatie
Published: October 2023

This research aims to describe the academic (teaching) supervision carried out by school principals to improve the competence of class teachers for children with special needs at SLBN-1 Palangka Raya. The approach used is a qualitative approach with the research subjects being the school principal and class teachers. Data collection was carried out through interviews, observation and documentation. Data analysis includes data reduction, data presentation and drawing conclusions. The results of the research show that academic supervision by the school principal is: (1) the principal's learning program planning is carried out by directing and guiding class teachers in making learning plans, (2) techniques for implementing supervision are carried out in groups and individually, namely through meetings and individual supervision. classroom visits, as well as clinical supervision according to teacher needs, and (3) supervision of evaluation of student learning outcomes carried out periodically to ensure learning achievement.
Economic Recession and Hotel Performance in Abia State, Nigeria
Authors: Onyeonoro C. O. , Okpaleke V. C. , Ononuju V.I , Onyeonoro F. N
Published: October 2023

Because of the economic crisis almost all businesses are navigating difficult times with severe consequences for employment and the whole economy. The initial economic downturn, has affected almost all sectors of the economy. The economic crisis leaded the companies cut off investments, wages, and reduced personnel. Nevertheless, the high rate of unemployment reduced workers’ income resulting to a further reduction of consumption. The whole situation simply feeds a recession cycle that cannot break without radical economic reform for the whole country and its economic activities. The main purpose of this paper is to empirically explore the influence of economic recession on hotel performance in Abia state, Nigeria. To achieve the objective of the study, survey research design was adopted. The researcher adopted primary data in getting the required information through the use of structured questionnaire. 210 management staff from 15 selected hotels in Abia State, Nigeria constitute the sample size of the study. Data collected were analyzed using multiple regression analysis. The findings revealed that economic recession (income rate, cost of production, and unemployment rate) has significant influence on customer patronage of hotels in the study area. The study recommends that government of Nigeria should work towards reducing the rising rate of inflation and other economic crisis to encourage businesses including hotel business in Nigeria. Also, Hotel industry in the midst of recession should cut down their cost of operation such as reducing unnecessary expenses that are not very important to the business. That would help in improving their performance