bluuebunny/crossref_metadata_2025 huggingface dataset:
Navigating Deepwaters - De-Risking and Early Monetization Opportunities with Early Production System Floater
Authors: Jie Tong Wen , Najib M Aiman B M , Rashid Abd Rais Abd , Suhaimi M Zulfaheem B , Rahman Nik Roshidan B A , Idrus Idzamani B , Saifuzzaman Syamsulzaidi B , Veroba Grant , Jaafar Abd Khalid
Published: February 2025

This paper explores early monetization and technical de-risking for deepwater field development through Early Production Systems (EPS), focusing on the selection study of Floating Production Facilities (FPF). EPS can mitigate risks associated with deepwater reservoirs by providing a cost-effective solution that accelerates initial oil production and improves reservoir understanding within one to two years. Developing the criteria for EPS selection involves collecting data from previous deepwater developments among major oil operators. The approach examines EPS strategies, categorized into redeploying existing FPFs to address reservoir uncertainty, advancing to Full Field Development facilities, or relocating EPS to multiple fields. The selection criteria aim to extend technical boundaries for affordable, rapid EPS solutions. Criteria for FPF selection include hull configurations, design operational life, and metocean conditions at the field location, aligning with the Minimum Technical Requirements (MTR) of EPS. The study made references to the past proven projects, which were successfully implemented in Offshore Malaysia water based on technology maturity, execution and operability risks in shallow water depth. This paper's novelty lies in outlining critical FPF selection criteria to facilitate early monetization and risk mitigation in Deepwater Full Field Development using EPS. Consequently, the technical limitations of FPF as an EPS solution are evaluated for their readiness to provide a technically sound, proven, and economically viable option for early deepwater production.
Resurrecting the Dead; One Well at a Time – An Innovative Approach Saves Time and Boosts Production
Authors: Hashim Qassim , Hamid Saad , Fayiz Mohammad , Khnaifir Waleed
Published: February 2025

The energy industry has a renewed focus towards enhancing production from brownfields. Revisiting dead wells in such fields presents an opportunity to not only revive but also at times prolong the productive life of a field. In gas condensate reservoirs, the phenomenon of liquid loading occurs as the reservoir pressure slides below dew point and liquid start to drop out from the gas phase. In severe liquid loading scenarios, wells cease to produce when the hydrostatic pressure of the liquid column becomes greater than the reservoir pressure. This paper discusses the common challenge of liquid loading in mature retrograde gas reservoirs over time. The paper also describes the best practices to identify, characterize and eventually revive the liquid loaded wells in a practical and cost-effective manner resulting in a significant boost to gas production.

Traditionally, the dead gas wells are considered prime candidates for either nitrogen lifting with coiled tubing or adding perforations in other prolific zones before resorting to re-entry. A holistic study of the production system, enables understanding of production dynamics. As a result, the liquid loading challenges can sometimes be solved in an efficient and cost-effective manner. Such a technique can be as simple as reducing the back pressure on a single well or a cluster of wells. The simplest yet the most effective way of determining this is by means of periodic pressure gradient surveys. This set of data is at times a regulatory requirement in some jurisdictions and is also readily available with operators who have comprehensive well surveillance and integrity management system.

Coupling the pressure surveys with a systems analysis approach, the candidates are shortlisted and qualified as economically feasible for production revival. The next step is to review the surface constraints which may involve debottlenecking the existing flowline network. Once the approach is executed, the well is observed for extended stable flow before accounting for production gain.

A pool of high potential candidate wells was shortlisted after thorough data analysis. Fresh gradient surveys were conducted on prospective wells. The technique was then applied to revive these wells one by one. As a result, a significant gas gain was realized from previously dead wells. Not only did the cost of expensive well intervention was avoided but also sustainable mid to long term production was achieved.

The experience and knowledge shared in this paper will serve as best practices for professional facing similar challenges with liquid loading. The simple yet effective way of quickly deploying this technique can bring immediate value to any organization or individual reading this paper.
О ФАКТОРАХ КОНКУРЕНТОСПОСОБНОСТИ РОССИЙСКИХ НЕФТЕДОБЫВАЮЩИХ КОМПАНИЙ
Authors: Зарипов А.М.
Published: February 2025

Cтатья посвящена исследованию роли российских нефтедобывающих компаний на мировом рынке энергоносителей. Выполнен анализ рейтинговых оценок по основным показателям функционирования компаний. Выделены и обоснованы внешние и внутренние факторы, влияющие на конкурентоспособность современных российских нефтедобывающих компаний.

Introduction. The mineral-raw materials market is an important component of the economy for any country. Oil, natural gas, and coal deposits in the country contribute to more efficient economy development as the domestic natural resources may be used for the production of goods and services. Besides, export of mineral raw materials enabling to replenish the budget of the country with export incomes is possible. The goal of the study is to make a scientific analysis of the role and place of Russian oil companies in the global market of energy products and reveal the major factors of competitive ability. Materials and methods. The scientific analysis was carried out on the basis of the study of ratings of largest Russian and foreign rating agencies. The study of development trends of energy products modern market and factors determining the competitive ability of Russian oil companies was carried with the use of factual data of IEA, Minenergo of Russia, and the statistics of Federal State Statistics Service. Results. According to the analysis results, PАО “NK Rosneft`”, PАО“Lukoil”, PАО “Gazpromneft`”. PАО “Surgutneftegaz”, PАО“Tatneft`” are the top five Russian oil companies for today. Russian oil companies are in the second top ten companies in the world ranking. The 2019-2020 crisis had a negative impact on the Russian economy, including oil companies performance. In 2020, the slowdown in rate of growth revenues from sales almost in all Russian oil companies was observed. Competitive ability of Russian oil companies is defined with both external and internal factors. The external factors of competitive ability include the world market conjuncture, which depends on the demand and offer flow on energy products of exporters and importers of mineral raw materials as well as the price trends for oil, natural gas, coal, and other energy resources. Technical state of companies, their investment activity, structure factor, effectiveness of state policy in this sector of economy and some other factors are the internal factors of competitive ability of oil companies. Conclusion. To improve the competitive ability of Russian oil companies, it is important to impose a new windfall profits tax that shall encourage companies to invest into the deposits with the highest aggregate value added maximum avoiding from manual control through targeted benefits.
ТЕХНОЛОГИЧЕСКАЯ МОДЕРНИЗАЦИЯ РЕГИОНА И ФАКТОР ПРЕДПРИНИМАТЕЛЬСКОГО ПОВЕДЕНИЯ
Authors: Полторыхина С.В.
Published: February 2025

Рассматривается проблема взаимосвязи технологической модернизации региона и факторов предпринимательского поведения. Проведён критический анализ понятия технологического уклада и подходов к определению предпринимательского поведения. Разработана схема личностного и группового целеполагания как основы смены технологических укладов. Установлена актуальность разработки предпринимательских управленческих решений нового типа.

Introduction. Today`s 6th technological mode is inextricably linked to the sweeping technological changes, which, in turn, require a completely new technological base establishment. This creates a prime importance of innovations, which most certainly change the approach to the economic systems, their structures, and institutions. Competitive entrepreneurial behavior plays a crucial role in the technological modes evolution. The goal of the study is to identify the relationship between the technological modernization of a region and factors of entrepreneurial behavior, determining the need in making the innovative managerial decisions. The task of the study is to make an analysis and a theoretical grounding of technological modes evolution from the perspective of the competitive entrepreneurial behavior as well as the study of modernization processes and the process of the technological mode change. Methods of analysis and synthesis, system analysis, and historico- evolutionistic institutional methods were used in the study. Results. In the context of earlier considered models of functioning and modernization of economic systems and the drivers for the technological mode change, the entrepreneurs act as an active start that can transform both means and factors of production and , in part, the communication environment, that is the institutional aspects of economic activity. Today the 6th technological mode, which is the newest one in the evolution stage, plays an important role in the competitive entrepreneurial behavior. This mode predetermined the change in the entrepreneurial managerial decisions. Conclusion. In the context of the 6thtechnological mode, elaboration of innovative entrepreneurial managerial decisions becomes important. The essence of this mode includes the simultaneous cost saving due to the elimination of insignificant competitive factors of external environment and implementation of the new ones and mitigation of risks of decision-making based on the analytical tools for value innovation creation which should be based on the parallel development of the innovation itself and its value in the eye of a consumer.
ОТ ДЕМОНСТРАТИВНОГО СВЕРХПОТРЕБЛЕНИЯ К УСТОЙЧИВОМУ ПОТРЕБЛЕНИЮ: КОНЦЕПЦИЯ ПЕРЕХОДА
Authors: Стрижак А.Ю. , Манчева И.К.
Published: February 2025

В статье исследована проблема демонстративного потребления в странах с рыночной экономикой. Исследованы социальные издержки производства и потребления продукции люксовых брендов. Разработана концепция перехода от демонстративного сверхпотребления к устойчивому потреблению в странах с развивающимися рынками.

Introduction. Demonstrative consumption as a form of wasteful use of resources is firmly rooted in the capitalist world and has become a kind of quasi-philosophy of modern society with its central ideological principle of utilitarianism. On the one hand, the demonstrative consumption can be a manifestation of social mobility; on the other hand, it brings about an array of socio-economic and environmental problems, creating an obstacle to effective sustainable development. The demonstrative consumption (especially in highly income-differentiated countries) poses a latent threat of status anxiety and often leads to social conflicts. The issue of shifting from demonstrative overconsumption to sustainable consumption in emerging markets is therefore highly topical and requires close attention from scientists, the state and the civil society institutions. This article is aimed at developing the concept of shifting from demonstrative overconsumption to sustainable consumption in emerging markets. Results. The normative approach to sustainable consumption requires the consumer to use resources with the highest marginal utility. However, consumer habits are due not so much to the functional as to the symbolic value of the product, and the consumption process itself is a complex symbiosis of heterogeneous social rules and clichés. Despite the social costs of consuming luxury goods, the traditional values of luxury brands have a strong impact on consumer behavior. Many luxury brands embed sustainability into a competitive business strategy. The problem of the transition of the society to sustainable consumption implies active participation of the state in the formation of appropriate institutions that affect consumer behavior: motivation, information, training, control, and enforcement. The shift from demonstrative overconsumption to sustainable consumption should evolve in a culturally sensitive manner of emerging markets. The authors proposed a concept for the transition to sustainable consumption in emerging markets that includes economic, sociocultural, legal and environmental practices, as well as related implementation tools. The result of the implementation of the concept will be the formation of a new culture of sustainable consumption in modern Russian society. Conclusion. The well-being of the society will depend on collective efforts to reduce income inequality and create a culture of sustainable production and consumption to conserve strategic resources and create new public goods towards effective economic development.
МЕТОД ОЦЕНКИ КРЕАТИВНОГО ЭКОНОМИЧЕСКОГО РАЗВИТИЯ РЕГИОНО
Authors: Евсеев А.С. , Урусова И.Н.
Published: February 2025

Предложено авторское определение креативного экономического развития регионов, творческого проекта, творческого актора. Разработан метод оценки креативного экономического развития регионов, который позволяет более полно оценить креативный потенциал региона, размеры креативного класса и специфику его деятельности, на основе чего определить миссии, стратегии социально-экономического развития региона.

The purpose of the study is to develop a method for assessing the creative economic development of regions. The research uses an integrated approach, as well as an abstract-logical and computational-constructive methods. Results. The authors' definitions of the creative economic development of regions, a creative project, and a creative actor were introduced; a method for assessing the creative economic development of regions was proposed. The factors influencing the creative economic development were also identified and clarified: the share of the creative class representatives among the total population of the region; the time spent by a creative class representative on the work on a creative project; the amount of funds and resources spent to accomplish a creative project; the quality of the work performed as reflected in the form of a realized manufactured product that has reached the consumer. Conclusion. The proposed method for assessing the creative economic development of regions allows for a fuller assessment of the creative potential in the region. The theoretical value of the paper materials is due to the fact that they develop the theory of creative class and deepen the understanding of the patterns of creative economic development in the region. In practice, the use of this method will make it possible to more accurately assess the size of the creative class and the specifics of its activities, and, based on this, to determine the missions, strategies, and programs for the socio-economic development of the region.
ФУНКЦИОНИРОВАНИЕ ТРАНСПОРТНОЙ ОТРАСЛИ В РЕСПУБЛИКЕ МАРИЙ ЭЛ: АНАЛИЗ И КЛАСТЕРИЗАЦИЯ
Authors: Игнашева Т.А.
Published: February 2025

В современных условиях активной автомобилизации населения как страны в целом, так и отдельных регионов особую актуальность приобретает вопрос оптимального планирования развития транспортной отрасли отдельных территорий. В зависимости от обеспеченности граждан отдельных районных образований автомобилями объёмы пассажирооборота в разных районах региона будут варьировать. Анализ объёмов пассажирооборота и грузооборота в разных группах позволит определить районы, в которых транспортный сектор развивается наиболее динамично, в том числе востребован со стороны населения в целях оптимального планирования развития транспорта региона.
АКТУАЛЬНОСТЬ И ЗНАЧЕНИЕ ESG-КОНЦЕПЦИИ ДЛЯ РОССИЙСКИХ ПРЕДПРИЯТИЙ В УСЛОВИЯХ ЭКОНОМИКИ ЗАМКНУТОГО ЦИКЛА
Authors: Гарипова Г.Р. , Уткина Е.И.
Published: February 2025

В настоящей статье раскрывается сущность и значение ESG-повестки, обозначена актуальность применения рассматриваемой концепции ESG. Дана характеристика и определено значение ESG-концепции для российских предприятий; рассмотрен опыт российских предприятий, применяющих ESG-концепцию; выявлены сложности в реализации ESG-проектов у российских предприятий. В результате проведённого анализа были выявлены российские компании, которые занимают высокие позиции ESG-рейтингов; рассмотрен опыт компаний, применяющих ESG-принципы в своей деятельности; обозначены основные трудности в реализации проектов с применением ESG-принципов.

Introduction. The current trends in the development of enterprises of the energy sector are shaping new demands on their functioning within the framework of transition to clean and resource-efficient energy. The purpose of this article is to determine the ESG concept application and significance for Russian enterprises in the context of circular economy. The ESG concept is one of the green economy thrusts which offers the state and business modern approaches to improving resource efficiency of enterprises, reducing the negative environmental impacts of production processes and manufactured goods, and addressing social issues, in particular resources, thus contributing to the achievement of the sustainable development goals. The ESG concept aims to propose effective business models for building environmentally responsible manufacturing and a system of rational use, which implies improving the quality of life and reducing inequalities within the population. The top 10 companies of the RAEX-Europe ESG rating were cited as those exemplifying good practices of the ESG concept implementation by Russian enterprises. The experience of SIBUR and Rosatom State Corporation is considered. For example, one of SIBUR’s overarching goals with regard to sustainable development is to make its enterprises carbon neutral by 2025. ROSATOM ensures sustainability of its internal processes in terms of environmental impact, management quality and the social sphere. At the same time, the main barriers to the implementation of the principles of the ESG concept in business systems include underfunding of programs for modernization of technical and technological processes and control systems, lack of technologies meeting circular economy needs, poor development of the consulting services market in this area, absence of a unified register or database on raw materials processing facilities or participants of the secondary raw materials sale and purchase market, as well as a low level of trust in the supply chains for materials, products and secondary raw materials. The conclusion is that the application of ESG principles has become one of the most important factors in modern business management. A circular economy requires improvement in the field of management.
РАЗВИТИЕ СТРОИТЕЛЬНЫХ ОРГАНИЗАЦИЙ И МЕТОДЫ ИЗМЕРЕНИЯ ИХ ПОТЕНЦИАЛА
Authors: Федосеев И.В. , Юденко М.Н.
Published: February 2025

Обоснована актуальность исследования влияния производительных сил и производственных отношений на развитие организаций сферы строительства, предложены методы измерения производительных сил, реализуемые на практике посредством применения показателей, которые имеются в статистической базе и непосредственно в деятельности организаций. Обосновано, что развитие организаций подчиняется законам диалектическо-материалистической онтологии. Предложена классификация видов потенциала строительных организаций и методы его измерения.

Introduction. The relevanceof the research theme is determined by the current economic trend necessitating the effective use of the main types of the enterprise potential that enable the achievement of strategic aims at the regional, sectoral and corporate levels, as is the case with the construction sector. The prerequisites of the study stem from the pertinence of finding solutions to the problem of forming and implementing the types of potential of construction organizations, also using methods of measurement and monitoring. The methods constitute the methodological basis promoting economic growth and development of the construction industry. The goal of the research is to determine the factors of economic development of construction as a type of economic activity, as well as their interaction with the main types of potential through the use of measurement methods. Research methods. In the course of the study, conventional methods of scientific research were employed including the method of the general theory of the development of economic and social systems according to the laws of dialectical-materialist ontology, as well as methods of economic analysis. Results and novelty. The study proposes two methodological approaches to determining the interaction of the forces of production in construction as a type of economic activity on the territory of the region. The key signs of development intrinsic to the nature of the development of material objects and economic entities of the economy were identified. Methods for measuring and quantitatively assessing the main types of the economic development potential of construction organizations were proposed. The methods increase the efficiency of managing the implementation of priority strategic guidelines of the economic development of enterprises. Conclusion. The suggested main types of the development potential of construction organizations are necessary and important benchmarks for the economic development of enterprises of the construction sector. In our view, the benchmarks can not only provide the greatest contribution to achieving the strategic aims and objectives of the construction industry development, but also ensure the quality of the economic growth of construction organizations through the interaction of productive forces and relations of production.
Detection and Quantification of Changes in Oligomeric States of STING at Attomolar Concentrations of Analyte
Authors: Lawless William , Eschenfelder Mark , Sparks Robert , Lawless Sarah , Krzypkowski Stephanie , Daniel Kenyon , Guida Wayne
Published: February 2025

Few protocols exist today that demonstrate repeatable resolution of small molecule interactions with target proteins at extremely low analyte levels, particularly at sub-femtomolar levels. We have developed two approaches for rapid screening and biophysical analysis which leverage changes in protein oligomer states to study highly potent small molecules. The first protocol employs microscale thermophoresis (MST) to measure competitive disruption of oligomerization following exposure of the target protein to its endogenous ligand. The second protocol engages dynamic light scattering (DLS) to measure the changes in physical size of oligomers after exposure to the endogenous ligand and/or analyte. STING (stimulator of interferon genes) is a protein that relies on oligomerization after ligand binding for intracellular signal transduction. Here we demonstrate the utilization of these methods through measurements of wild type STING oligomerization following exposure to 2’,3’-cGAMP and the compound clonixeril along with several analogs. Using these techniques, one can now measure small molecule inhibitor concentrations in the attomolar range when the target protein undergoes oligomerization as part of its natural biological activity.
A Deep Learning-Augmented Density Functional Framework for Reaction Modeling with Chemical Accuracy
Authors: Xiao Jin , Zhang Yingfeng , Li Bowen , Zhang Shuwen , Gao Ya , Wang Han , Zhang John Z.H. , Zhu Tong
Published: February 2025

Accurate prediction of reaction energetics remains a fundamental challenge in computational chemistry, as conventional density functional theory (DFT) often fails to reconcile high accuracy with computational effi ciency. Here, we introduce Deep post-Hartree-Fock (DeePHF), a machine learning framework that synergistically integrates neural networks with quantum mechanical descriptors to achieve CCSD(T)-level precision while retaining the efficiency of DFT. By establishing a direct mapping between the eigenvalues of local density matrices and high-level correlation energies, DeePHF circumvents the traditional accuracy-scalability trade-off . Trained on a limited dataset of small-molecule reactions, our method demonstrates unprecedented performance across multiple benchmark datasets, exhibiting exceptional transferability. In fact, its accuracy even surpasses that of advanced double-hybrid functionals, all while maintaining O(N^3) scaling. DeePHF offers a promising pathway to bridge the gap between high-level quantum chemistry methods and the practical demands for scalable, accurate models in computational chemistry, and with further refi nement, it is poised to make signifi cant contributions to the advancement of chemical reaction modeling.
Automated Flow Synthesis of Combinatorial Protein Libraries
Authors: Johnson Corey , Vithanage Dimuthu A. , Lee Gha Young , Pentelute Bradley L. , Albin John S.
Published: February 2025

Flow synthesis with building block mixtures permits the generation of hyperdiverse polyamide libraries on a timescale of < 1 hour per library. The semi-automated flow platform on which we have previously developed this technique, howev-er, lacks the efficiency required to make protein-length polyamide chains. To facilitate the direct engraftment of diversity regions into longer polyamide chains, we adapted mixture-based library synthesis to automated flow peptide synthesis (AFPS) systems previously optimized for the production of 100-200-mer proteins. Using this approach, we demonstrate the ability to generate a 101-mer protein library with a diversity approaching quintillions of members. AFPS thus permits the incorporation of hyperdiverse polyamide libraries into synthetic protein scaffolds.
Graphically revealing weak interactions in dynamic environments using amIGM method
Authors: Lu Tian
Published: February 2025

Visualization of weak interactions is now a very popular kind of analysis methods, which allows chemists to recognize existence, strength, and type of interactions in different regions of a chemical system easily and intuitively. Among these analysis methods, the independent gradient model (IGM) and its variant with better graphical effect, namely IGM based on Hirshfeld partition of molecular density (IGMH), are particularly useful. They can clearly reveal various interactions between specific fragments, and become widely popular in recent years. This chapter first briefly reviews the definition and characteristics of the two methods, and then introduces a new variant of IGM, called modified IGM (mIGM), which, like IGM, only requires atomic coordinate information to perform the analysis and thus the computational cost is fairly low, while its graphical quality in exhibiting weak interactions is almost as good as the markedly more expensive IGMH. This chapter then introduces the averaged mIGM (amIGM) method, which extends mIGM to visual analysis of the weak interactions involved in molecular dynamics trajectories. A series of examples fully demonstrate that amIGM can well display all kinds of weak interactions in dynamic environments, and its image quality and flexibility are all superior to the previously proposed averaged noncovalent interaction (aNCI) method with similar uses.
Features of complex therapy of hemorrhagic fever with renal syndrome against the background of liver damage
Authors: Shuldyakov Andrey A. , Lyapina Elena Р. , Smagina Anna N. , Lisko Olga В.
Published: February 2025

Aim. To evaluate the effectiveness of hepatoprotective support in patients with hemorrhagic fever with renal syndrome (HFRS) with cytolytic syndrome by using the combined drug Remaxol®.
Materials and methods. 60 patients with HFRS were examined: 43 (71.7%) men, 17 (28.3%) women, the average age of patients was 41.4±2.3 years. The subjects were divided into 2 groups (30 people each). Study design: open, randomized, comparative.
Results. The analysis of the use of the drug Remaxol® was carried out as a means of hepatotropic support for patients with HFRS with liver damage. When evaluating the dynamics of clinical and laboratory parameters characterizing liver functionality in 2 groups of patients receiving intravenous infusions of Remaxol® (400.0 ml) or active placebo (400.0 ml 0.9% sodium chloride solution) for 10 days, it was shown that the use of Remaxol® as a hepatoprotector in the complex treatment of patients HFRS with cytolysis syndrome contributes to the dynamic stabilization of biochemical parameters of liver function and normalization of its size.
Conclusion. The use of Remaxol® as part of the complex pathogenetic therapy of patients with HFRS with liver damage makes it possible to accelerate the disappearance of cytolytic syndrome, as well as laboratory indicators of cholestasis. The good tolerability of Remaxol® and the absence of significant side effects make it possible to recommend its wide use in this cohort of patients.
How Can We Make Independent Public Policy Institutions a Less Fragile Species?
Authors: Rosenberg Bill
Published: February 2025

In late November 2023 the staff and commissioners of the New Zealand Productivity Commission Te Kōmihana Whai Hua o Aotearoa were shocked to learn that the newly elected coalition government would be abolishing the commission. It was disestablished just three months later, having functioned for 13 years. The commission’s primary task was to provide the government with independent policy advice, via inquiries requested by the government of the day. From an historical perspective, the commission’s closure was unfortunately par for the course. Few independent government institutions providing economic and social policy advice have survived even that long. This article explores the factors which contribute to these short lives, and the factors which contribute to the effectiveness of such institutions, and suggests ways in which they can be made less fragile.
Te Aorerekura : towards eliminating family violence – reflections from the Atawhai project
Authors: Eppel Elizabeth , Gear Claire , Hape Hazel , Koziol-McLain Jane , Rolleston Anna , Timutimu Ngareta , Ahomiro Hori , Healy Clare , Hegarty Kelsey , Isham Claire
Published: February 2025

Family violence is an under-recognised contributor to ill-health. Atawhai, a three-year research project focusing on sustainable responses to family violence in primary healthcare services, suggests that relationships and networks among locality-based service providers and local communities will help in making New Zealand’s strategy to eliminate family violence a reality. More is needed than joining up the government agencies delivering services to those experiencing family violence. Building relationships between communities and healthcare providers to harness the contextual and cultural knowledge of those most affected has to be integral to a sustainable response that begins to address the causes of this wicked problem, along with developing place-based solutions.
Opportunities and Challenges of Big Data Empowering Clinical Medicine Graduate Education from the Perspective of Ideological and Political Guidance
Authors: Liu Ying , Chang Yuqiao
Published: February 2025

This study explores the theme of “Big Data Empowering Clinical Medicine Graduate Education from the Perspective of Ideological and Political Guidance.” It examines how big data technology can enhance the quality of graduate education in clinical medicine. By analyzing the integration of ideological and political guidance theory with big data technology, this paper aims to uncover the potential opportunities and challenges of big data in improving clinical medicine graduate education. The research employs literature review and case study methods to delve into the potential applications of big data technology in curriculum design, teaching quality monitoring, student evaluation, and personalized learning support. The results indicate that big data technology provides new tools and methods for clinical medicine graduate education, contributing to the personalization, precision, and efficiency of education. However, the application of big data technology also faces challenges such as data privacy protection and transparency in technology application. This study offers theoretical support and practical guidance for the introduction of big data technology in the field of clinical medicine graduate education, holding significant implications for promoting the innovation and development of educational technology.
A Preliminary Study of Multimodal Discourse to Promote the Teaching of Chinese for Specific Purposes
Authors: Ma Haoran
Published: February 2025

With the increasing global demand for Chinese language, the teaching of Chinese for Specific Purposes (CSP) has occupied an increasingly important position in the teaching of Chinese as a foreign language. However, traditional teaching methods often neglect the role of non-verbal symbols in language comprehension and communication. The multimodal discourse theory provides a new perspective for CSP teaching, which can effectively enhance students’ understanding and mastery of specialized terminology and language application skills by integrating multisensory symbol systems such as language, vision, hearing, and touch. This paper starts from the current situation of teaching CSP and analyzes the adaptability between multimodal discourse and CSP teaching, aiming to provide theoretical support and practical suggestions for the innovation of the teaching mode of CSP.
Constructing a Multi-Dimensional Governance System for the Application of Generative AI in Schools: Policy Analysis and Implications of the “Australian Framework for Generative AI in Schools”
Authors: Liu Lanting
Published: February 2025

With the rapid development of generative artificial intelligence (AI) technology in the field of education, global educational systems are facing unprecedented opportunities and challenges, urgently requiring the establishment of comprehensive, flexible, and forward-looking governance solutions. The “Australian Framework for Generative AI in Schools” builds a multi-dimensional governance system covering aspects such as teaching and humanistic care, fairness and transparency, and accountability and security. Based on 22 specific principles and six core elements, it emphasizes a human-centered design concept, adopts a principle-based flexible structure, focuses on fairness and transparency, and stresses accountability and security. The framework provides valuable references for the use of generative AI in China’s education system and holds significant importance for promoting educational modernization and cultivating innovative talents adapted to the era of artificial intelligence.
Teaching Design for the Elementary Chinese Comprehensive Course “My Family” Based on Multimodal Theory
Authors: Ji Yini
Published: February 2025

With the rapid development of Teaching Chinese as a Foreign Language (TCFL), improving teaching quality requires integrating advanced pedagogical concepts. Multimodal teaching, which employs various symbolic modes to engage students’ multiple senses, is a highly effective approach. Introducing multimodal theory into TCFL education can enhance teaching efficiency and improve students’ communication skills. This paper applies multimodal theory to TCFL, using the elementary Chinese comprehensive course “My Family” as a case study to propose a detailed teaching design, followed by evaluation and reflection. The aim of this teaching design is to deepen the understanding of multimodal theory and provide additional reference for the TCFL.
Clinical Study on the Modified Formula of Huang Yuanyu’s Gui Fu Ling Wu Decoction for Treating Spleen-Kidney Yang Deficiency Type Diabetic Nephropathy
Authors: Liu Xiaoqin , Zhou Xiaoping , Wang Wen , Li Meiji , Zhang Qian , Zhai Xiaoxia , Yu Kexin
Published: February 2025

Objective: To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy (DN) of the spleen-kidney Yang deficiency type. Methods: A total of 100 DN patients admitted to Changyi Traditional Chinese Medicine Hospital between August 2023 and March 2024 were included in the study. Patients were randomly divided into a control group and a study group, each comprising 50 cases, using a computerized random number generator. The control group received kallikrein treatment, while the study group received a combination of kallikrein and the modified Gui Fu Ling Wu Decoction. Blood glucose control, renal function, and inflammatory markers were assessed before and after treatment in both groups. Results: Before treatment, there were no significant differences in blood glucose and renal function indicators between the two groups (P > 0.05). After treatment, postprandial blood glucose, fasting blood glucose, 24-hour urinary protein, urinary microalbumin, serum creatinine, serum C-reactive protein (CRP), and interleukin-6 levels significantly decreased in both groups, with the study group showing superior results compared to the control group (P < 0.05). Conclusion: The combination of Gui Fu Ling Wu Decoction and kallikrein for treating spleen-kidney Yang deficiency type DN significantly improves blood glucose control, enhances renal function, and reduces inflammatory responses.
Effect of Artificial Hip Replacement Surgery on the Treatment of Intertrochanteric Femur Fractures in Elderly Patients and Its Impact on Hip Joint Function and Quality of Life
Authors: Qin Yong , Xu Jianfei , Feng Dongqian , Zhang Bin
Published: February 2025

Objective: To evaluate the treatment effect of total hip arthroplasty (THA) for intertrochanteric femur fractures (IFF) in elderly patients. Methods: Thirty-two elderly patients with IFF admitted to the hospital from August 2021 to August 2024 were selected and randomly divided into two groups using a random number table. The experimental group (16 patients) underwent THA surgery, while the control group (16 patients) underwent proximal femoral nail antirotation (PFNA) surgery. Hip joint function and quality of life indicators were compared between the two groups. Results: Before surgery, there was no significant difference in hip joint function and quality of life scores between the two groups (P > 0.05). However, at six months postoperatively, the experimental group had higher hip joint function and quality of life scores compared to the control group (P < 0.05). The total effective rate was higher in the experimental group than in the control group (P < 0.05). The complication rate in the experimental group was similar to that in the control group (P > 0.05). Conclusion: THA can improve the clinical efficacy of elderly patients with IFF, minimize postoperative complications, effectively restore hip joint function, and optimize postoperative quality of life.
The Clinical Significance of the Emergency Green Channel in the Treatment of Patients with Acute Chest Pain
Authors: Li Congying , Zhang Yi
Published: February 2025

Objective: To analyze the clinical significance of the emergency green channel in the treatment of patients with acute chest pain. Methods: Sixty patients with acute chest pain treated between September 2022 and July 2024 were selected as the subjects of this study. They were divided into groups based on the order of treatment: the first 30 patients were included in the Green Channel group, where the emergency green channel was employed, while the remaining 30 patients were placed in the Regular Emergency group, receiving standard emergency treatment. The rescue time, hospitalization time, pain scores, incidence of adverse reactions, and quality of life between the Green Channel group and the Regular Emergency group were compared. Results: The rescue time and hospitalization time of the Green Channel group were shorter than those of the Regular Emergency group, with statistical significance (P < 0.05). The pain scores at 30, 60, 120, and 240 minutes after rescue in the Green Channel group were lower than those in the Regular Emergency group, with statistical significance (P < 0.05). The incidence of adverse reactions such as recurrent acute attacks, arrhythmia, heart failure, stroke, and shock in the Green Channel group was lower than that in the Regular Emergency group, with statistical significance (P < 0.05). The treatment satisfaction rate and success rate in the Green Channel group were 93.33% and 93.33%, respectively, while those in the Regular Emergency group were 73.33% and 73.33%. Both the satisfaction and success rates in the Green Channel group were higher than those in the Regular Emergency group, with statistical significance (P < 0.05). The quality of life in the Green Channel group was also higher than that in the Regular Emergency group, with statistical significance (P < 0.05). Conclusion: The emergency green channel plays a significant role in the treatment of patients with acute chest pain and is worthy of widespread clinical application.
Impact of Preoperative Psychological Interventions on Patients Undergoing Elective Surgery
Authors: Yang Jianqiang
Published: February 2025

Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department between August 2021 and August 2023 were selected and divided into groups using a random number table. The observation group received preoperative psychological interventions, while the reference group received standard preoperative care. Anxiety and depression scores, fear grading, vital signs, and self-efficacy levels were compared. Results: After the intervention, the anxiety and depression scores in the observation group were lower than those in the reference group, and the proportion of fear graded as Level I was higher. During the waiting period and 15 minutes before entering the operating room, vital sign levels in the observation group were lower than those in the reference group. Additionally, the self-efficacy scores of the observation group were significantly higher than those of the reference group (P < 0.05). Conclusion: Preoperative psychological interventions can alleviate negative emotions, stabilize preoperative vital signs, and significantly improve self-efficacy in patients undergoing elective surgery, demonstrating high feasibility for implementation.
Effect of Ultra-Early Hemoperfusion on Emergency Treatment Outcomes in Patients with Severe Organophosphate Pesticide Poisoning
Authors: Yang Jianyu
Published: February 2025

Objective: To analyze the emergency treatment effect of ultra-early hemoperfusion (HP) in patients with severe organophosphate pesticide poisoning (SOPP). Methods: Sixty SOPP patients treated in the emergency department between January 2022 and January 2024 were randomly divided into two groups using a random number table. The observation group (30 cases) received ultra-early HP treatment, while the reference group (30 cases) received conventional HP treatment initiated 6 hours post-poisoning. The groups were compared in terms of overall emergency efficacy, clinical indicators, serological markers, inflammatory factors, and complication rates. Results: The observation group had a higher total efficacy rate than the reference group, superior clinical indicators, and a lower complication rate (P < 0.05). After 24 hours of emergency treatment, serological markers and inflammatory factor levels in the observation group were lower than those in the reference group (P < 0.05). Conclusion: Ultra-early HP treatment provides better emergency outcomes for SOPP patients by shortening treatment time, improving serological markers and inflammatory factor levels, and offering higher safety. It demonstrates significant advantages in emergency care.
Mathematical symmetries of the binakul textiles
Authors: De Las Peñas Louise Antonette , Salvador-Amores Analyn , Tomenes Mark D. , Taganap Eduard C.
Published: February 2025

This paper presents a method to analyze the layer symmetry structure of a textile, representing it as a two-way twofold fabric and applying notions of color symmetry to its corresponding design. In particular, it presents an analysis of the symmetry structures of the binakul textiles or binakul of the Itneg, an ethnic group located in the northern part of the Philippines. The layer symmetry groups of the binakul are determined. Results reveal that the symmetries of the binakul consists of side preserving isometries.
Symmetry in musical spaces
Authors: Lee S. P. Kathryn , Ooi C. H. Raymond , Wang Ita
Published: February 2025

An analysis of symmetry was applied to the Bach Violin Chaconne (BWV 1004, c.1720) and modern Piano Chaconne by Sofia Gubaidulina (c.1962). Excerpts from musical contours may appear in symmetrical forms (1Apagyi, 1989,5 Donnini, 1986, 9Morgan, 1998 & 10Voloshinov, 1996) and more interestingly as recontextualized form (Hanninen,2003)6. This study explores the drawing of music in symmetry by an illustrative pitch height (y-axis) against time (x-axis) topology.
A Comparative Study of Traditional Statistical Methods and Machine Learning Techniques for Improved Predictive Models
Authors: Alanazi Bader S
Published: February 2025

The financial sector has undergone a major transformation through the incorporation of machine learning (ML) techniques, improving decision-making and predictive accuracy. This research explores the application of several ML algorithms to a dataset of historical stock prices to forecast future price movements. We conduct a comparative analysis of traditional models, including linear regression, and advanced ML techniques, including random forests, decision trees, and approaches like Long Short-Term Memory (LSTM) networks. Our analysis reveals that while traditional models establish a baseline, advanced techniques substantially outperform them regarding accuracy and reliability. This research also emphasizes the ethical challenges of using machine learning in finance, particularly in terms of model interpretability and data privacy.
K-Frames in Super Hilbert C∗-Modules
Authors: Lfounoune Abdellatif , El Jazzar Roumaissae
Published: February 2025

In this paper, we study the theory of K-frames in super Hilbert C∗-modules. We introduce the concept of super Hilbert modules as direct sums of Hilbert C∗-modules and explore how frames and K-frames can be defined and characterized within this framework. Our main results provide new characterizations of K-frames in super Hilbert C∗-modules, as well as necessary and sufficient conditions under which sequences in super Hilbert C∗-modules form K-frames. Additionally, we investigate the relationships between K-frames, minimal frames, and orthonormal bases, offering several propositions and illustrative examples. These findings extend the existing frame theory in Hilbert spaces to the richer structure of Hilbert C∗-modules, thereby contributing to a deeper understanding of operator theory and functional analysis in the context of C∗-algebras.