bluuebunny/crossref_metadata_2025 huggingface dataset:
Telecolaboração em uma rede de pesquisa internacional
Authors: RAMOS Karin Adriane Henschel Pobbe , CARVALHO Kelly Cristiane Henschel Pobbe de
Published: June 2022

Os processos de internacionalização institucional têm sido uma preocupação constante entre os pesquisadores universitários em todo o mundo, considerando a urgente demanda da comunidade acadêmica em contribuir para a solução dos problemas da sociedade contemporânea (BRENNAN; KING; LEBEAU, 2004), especialmente considerando os cenários pandêmico e pós-pandêmico. Este estudo tem como objetivo discutir uma experiência que vem sendo desenvolvida sobre a divulgação da cultura, da língua e da literatura em contextos de intercâmbio virtual (O’DOWD; LEWIS, 2016). As ações são desenvolvidas em parcerias entre universidades, entre as quais já existe um histórico de atividades relacionadas ao projeto “Teletandem Brasil” (TELLES; VASSALO, 2006). Esses estudos estão vinculados a uma rede internacional de pesquisa do Programa Capes-PrInt-UNESP, intitulado “Difusão de cultura, língua e literatura em contextos de telecolaboração”. As reflexões empreendidas, neste trabalho, baseiam-se nas seguintes preocupações: (a) como os estudos sobre telecolaboração têm contribuído para o processo de internacionalização da instituição envolvida; (b) quais são as contribuições dessas pesquisas para a democratização do acesso a bens culturais, linguísticos e literários. A importância dessas discussões reside na constituição de um espaço de estudos sobre os processos de internacionalização institucional e permite traçar ações de enfrentamento aos desafios futuros.
Telecollaboration and Linguistic Gains in Postsecondary Non-Native Portuguese Learning
Authors: MAIMONE Luciane , ZACH Ariel ZACH
Published: June 2022

This study sought to investigate linguistic gains and crosslinguistic influence (CLI) from English and Spanish on the oral production of postsecondary L3 Portuguese learners, comparing the effects of two pedagogical approaches: oral synchronous telecollaboration between Portuguese learners and native speakers (Teletandem), and group work among learners in the L2 classroom. Participants met weekly for eight weeks, after which gains in oral proficiency were measured using an Elicited Imitation Task (EIT) and a listening comprehension test (LCT). Linguistic development was also measured by various indices of oral complexity, accuracy, and fluency (CAF). Results showed significant improvement in proficiency and all CAF measures over time, but no differences between groups. Spanish CLI was significantly higher than English CLI for both groups and the only type of CLI to significantly decrease. Participants' perceptions and beliefs, and the lack of differential performance across groups is discussed, considering different pedagogical and theoretical approaches to telecollaboration.
Membrane Technology for Water Pollution Control: A Review of Recent Hybrid Mechanism
Authors: Martini Sri
Published: June 2022

Current development of membrane technology for purifying polluted water and wastewater is discussed in this review in accordance with its hybrid application with other types of water treatment methods such as adsorption, advanced oxidation processes (AOPs), and biological activated sludge.  This hybrid implementation aims are to lengthen membrane lifespan and elude severe fouling on the surface and pore of the membrane. Membrane material and fabrication technology were concisely included. Two prominent materials to fabricate membrane namely polymeric and ceramic are reviewed well along with the exploration of biopolymers based-materials such as starch and alginate. Several fabrication methods available to be implemented in research or industrial large scale including interfacial polymerization technique, non-solvent induced phase separation, temperature induced phase separation, electrospinning, and sintering are deliberately discussed. The next section includes fouling analysis involving reliable fouling mechanism namely Hermia’s models to help with the explanation of fouling occurrence during filtration. These models covers four different mechanisms namely complete blocking, standard blocking, intermediate blocking, and cake filtration models. Ultimately, recent research reporting the outcome of the hybridization of membrane and adsorption, biosorption, coagulation-flocculation, AOPs, and biological treatment using microorganism were properly reviewed.  Overall, this review considerably promotes the findings of those works which mostly revealed positive outcome of the hybrid membrane system contributing to stronger foundation for future research.
Vyrazhennost' kognitivnyh i nevrologicheskih narushenij u krys posle ishemicheskogo insul'ta na fone primeneniya ksenona 0,5 MAK
Authors: Крюков И. А. , Ершов А. В. , Черпаков Р. А. , Гребенчиков О. А.
Published: June 2022

U podavlyayushchego chisla pacientov, perenesshih ostroe narushenie mozgovogo krovoobrashcheniya, vyyavlyayutsya ostatochnye yavleniya, iz nih u 50% — kognitivnye narusheniya, ogranichivayushchie samoobsluzhivanie v bytu, trudovuyu deyatel'nost' i social'nuyu adaptaciyu v celom i privodyashchie k invalidnosti dazhe pri otsutstvii znachitel'nyh dvigatel'nyh narushenij. Cel'yu issledovaniya bylo podobrat' naibolee effektivnuyu prodolzhitel'nost' ingalyacii ksenona s 0,5 MAK (maksimal'noj al'veolyarnoj koncentraciej) dlya snizheniya vyrazhennosti nevrologicheskih i kognitivnyh narushenij pri eksperimental'nom insul'te. Na 70 krysah smodelirovana fokal'naya ishemiya-reperfuziya po metodu Longa s posleduyushchej ingalyaciej ksenona 0,5 MAK v techenie 30, 60 ili 120 min. Nevrologicheskij deficit ocenivali s pomoshch'yu serii iz semi testov «Postanovka konechnosti na oporu», kognitivnye funkcii — testom «Vodnyj labirint Morrisa». Ekspoziciya ksenona 0,5 MAK v techenie 30 min privodila k rostu chisla ballov v teste «Postanovka konechnosti na oporu» na 40% (r = 0,055) i umen'sheniyu latentnogo vremeni v teste «Vodnyj labirint Morrisa» na 17,6% (r = 0,08) po sravneniyu s kontrol'noj gruppoj, ekspoziciya v techenie 60 min — v 2 raza (r = 0,01) i na 44,4% (r = 0,04), v techenie 120 min — tozhe v 2 raza (r = 0,01) v oboih testah sootvetstvenno. Sdelan vyvod, chto ingalyaciya ksenona 0,5 MAK pri ekspozicii 30 min ne privodit k znachitel'nomu uluchsheniyu sostoyaniya zhivotnyh i ih sposobnosti k obucheniyu, o chem svidetel'stvuet otsutstvie statisticheski znachimyh razlichij. Ekspoziciya zhe ksenona v techenie 60 min znachitel'no umen'shaet nevrologicheskij i kognitivnyj deficit v gruppe issledovaniya, a uvelichenie vremeni ekspozicii ksenona do 120 min okazyvaet sopostavimyj effekt.
Educar a Eros. Juan Lazarte y la difusión de saberes sexuales
Authors: Ledesma Prietto Nadia
Published: June 2022

Este artículo explora el rol del médico anarquista Juan Lazarte como difusor de conocimientos sobre la sexualidad, a partir del análisis de su columna “Curso de Sexología” publicada en la revista Hombre de América Fuerte y Libre y de la dirección de la Colección Eros de la editorial Partenón. Se propone situar a Lazarte como uno de los representantes de una sexología anarquista que se preocupó por la educación sexual, para prevenir enfermedades y también para liberar el placer sexual de la reproducción, la institución matrimonial y la prostitución. A través del análisis crítico del discurso se aborda su práctica discursiva respecto de los saberes sobre la sexualidad que consideraba necesario difundir a un público amplio, ya sea por medio de sus propias intervenciones o de la selección de obras que formaron parte de Eros. Este análisis intenta aportar al campo de estudio de la sexología al examinar otras periodizaciones y conceptualizaciones, incorporando las ideas y prácticas anarquistas en la genealogía de un campo sexológico local.
Solitary cutaneous mastocytoma on the scalp of a child; a case report and review of literature
Authors: Bahadoram M. , Joonaki Y. , Yaghoobi Reza , Mahmoudian-Sani M.-R. , Hassanzadeh S. , Bahadoram S.
Published: June 2022

Mastocytomas are solitary mast cell tumors that are generally seen on the trunk and extremities. Childhood-onset mastocytomas of the scalp are extremely rare. We report a case of a one-and-a-half-year-old toddler boy that presented with a yellow-brown plaque on his scalp. Pathological evaluation s revealed mast cell accumulation in the upper dermis. These cells were uniform with a fried-egg appearance and had visible cytoplasmic granules with Wright-Giemsa staining. This study demonstrates the difficulty of diagnosing soli¬tary mastocytomas as it is a very rare disease and has non-specific clinical findings. In this study, a child with a rare solitary cutaneous mastocytoma on the scalp was evaluated and a review of previous literature was conducted.
The potential of impulse oscillometry in lung function assessment in children after allogeneic hematopoietic stem cell transplantation
Authors: Kudinova T. V. , Skvortsova Yu. V. , Bostanov D. E.
Published: June 2022

The article analyzes the potential of using impulse oscillometry in the diagnosis of respiratory disorders in children with oncological and hematological diseases after allogeneic hematopoietic stem cell transplantation (HSCT). The study was approved by the Independent Ethics Committee and the Scientific Council of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation. A comparative analysis of parameters of impulse oscillometry and spirometry before and on Days 30, 90, 180 and 360 after HSCT was carried out. It was revealed that pulmonary ventilation function impairments are quite common in this group of patients, worsening significantly by month 3 of follow-up. An increase in reactance at a frequency of 5 Hz is one of the earliest signs of impaired respiratory function, which can be used for timely diagnosis of pulmonary complications after allogeneic HSCT.
Towards assisted rationality switching in negotiations
Authors: Nieciecka Weronika , Szapiro Tomasz
Published: June 2022

The text attempts to provide a comprehensive outlook on negotiation processes and support procedures, by deriving a mathematical description based on psychological and managerial context. The authors merge psychological and formal descriptions of the principles underlying the perception of rationality in negotiation problems. The framework allows for explaining the violation of perceived rationality as a result of the deprivation of human needs. The argument, supported by pilot experiments, allows for recommending a procedural approach to negotiation, focused on monitoring perceptions of rationality of proposal submission. The paper is concluded with an attempt to foresight further developments of theoretical investigations and expansion of application fields.
Diagnostic Model of Aircraft Turbine Engine Governor Pump
Authors: Ohanian Ihor , Yepifanov Sergiy
Published: June 2022

This paper presents a mathematical model for a hydromechanical fuel governor pump, to be used in parametric diagnostics. The design and operation of the governor are described. The main requirements of the model are formulated, its structure is determined, corresponding to the specifics of the diagnostic task, and assumptions to make the model simpler are presented (single-dimensional flow and absence of heat exchange). The presented model consists of idealized elements with lumped parameters (such as pressure and mass consumption of the working fluid), accounting for the compressibility of the substance and the design arrangement of the governor (presence of mechanical rests, metering orifices of complex shapes, relay switchers, etc.). Equations of elements with lumped parameters, linked by hydraulic channels in one node, are presented. The model – a system of first-order differential-algebraic equations – is solved and the parameters of the governor pump are determined for different steady-state and transient operation modes. We compare our results to the requirements for the corresponding parameters outlined in the Engineering Specifications. The model is matched to the specifications by correcting setting parameters (tightening of elastic springs, areas of throttles, etc.), and a method of initial model linearization is developed. Based on the results, we conclude that our model can be used as a diagnostic algorithm for a governor pump, at the testing and development stages, during manufacturing, repair and maintenance.
Successful management of patent ductus arteriosus in severely malnourished boy
Authors: Koentartiwi Dyahris
Published: June 2022

Background: Patent ductus arteriosus is a vascular structure that connects the proximal descending aorta to the roof of the main pulmonary artery near the origin of the left branch pulmonary artery results in congestive heart failure, pulmonary hypertension, recurrent pneumonia and severe malnutrition. Transcatheter closure of PDA usually performed for the body weight above 6 kilograms, this is our first case in our hospital to close PDA in a child with the body weight less than 6 kilograms with satisfactory result.
Prevalensi dan faktor risiko prehipertensi dan hipertensi pada mahasiswa tingkat akhir Fakultas Kedokteran Universitas Riau
Authors: Hardiman Revinta Mozache , Siregar Fajri Marindra
Published: June 2022

Hipertensi merupakan masalah kesehatan nasional yang paling sering dijumpai di fasilitas layanan kesehatan primer. Prehipertensi bukan penyakit, melainkan berupa pengingat untuk menurunkan tekanan darah sebelum berada dalam kondisi hipertensi dan komplikasinya. Belakangan ini, kasus prehipertensi dan hipertensi meningkat pada dewasa muda (18-39 tahun) dan sering kali tidak terdiagnosis. Tujuan dari penelitian ini adalah mengetahui prevalensi dan faktor risiko prehipertensi dan hipertensi pada mahasiswa tingkat akhir Fakultas Kedokteran Universitas Riau. Penelitian ini merupakan penelitian deskriptif observasional yang dilaksanakan pada Oktober 2020 – April 2021. Data penelitian diperoleh dari 118 responden yang terdiri dari 33 orang (28%) laki-laki dan 85 orang (72%) perempuan. Hasil penelitian ini adalah ditemukan prevalensi prehipertensi sebesar 34,7% dan hipertensi sebesar 5,9%. Faktor risiko yang didapatkan meliputi jenis kelamin laki-laki 28%, riwayat hipertensi keluarga 81,4%, indeks massa tubuh overweight 13,6% dan obesitas 22,9%, aktifitas fisik rendah 54,2%, perokok 3,4% dan ex-perokok 4,2%, konsumsi alkohol 5,9%, pola makan buruk 63,9%, tingkat stres parah 12,7% dan sangat parah 11%, dan kualitas tidur buruk 87,3%.
PENENTUAN KRITERIA DERAJAT LUKA DALAM VISUM ET REPERTUM & ANALISIS MEDIKOLEGAL PADA KORBAN KECELAKAAN LALU LINTAS
Authors: Perwira Satria
Published: June 2022

Background: A traffic accident is an unexpected and unintentional event involving a vehicle with or without other road users which causes human victims to suffer minor injuries, moderate injuries, and serious injuries.Case Presentation: A letter has been received for a request for Visum et Repertum (VeR) Luka from the Surabaya Police with a statement that the person is suspected to have suffered traffic accident injuries on Jalan Raya Medokan Sawah on September 21, 2021 at 10.00 WIB. General examination, wounds and support were carried out. The results of the examination and the conclusion of the degree of injury are then written into a VeR.Conclusion: VeR serves as legal evidence, as evidence for the detention of suspects, and as material for judge's consideration. The application of the degree of injury in the writing of the conclusion of the VeR does not mention the degree of injury, but the impact is stated as formulated in the criminal provisions in the Criminal Code or other laws.
NEW DEVELOPMENT OPPORTUNITIES MARINE ELECTRIC PROPULSION SYSTEMS
Authors:   Krylov State Research Centre, St. Petersburg, Russia, Savchenko О.V. , Ljapidov K.S. ,   Krylov State Research Centre, St. Petersburg, Russia, Polovinkin V.N. ,   Krylov State Research Centre, St. Petersburg, Russia, Kalinin I.M. ,   Krylov State Research Centre, St. Petersburg, Russia, Nikolaev M.A. ,   Moscow Institute of Electronic Technology, Osipa S.I. ,   CJSC "Institute of Telecommunications"
Published: June 2022

В монографии сделан обстоятельный анализ энергетических установок (ЭУ) и систем электродвижения (СЭД) кораблей ВМФ и судов гражданского флота, рассмотрены планы строительства судов с электродвижением, а также проблемы создания систем электродвижения кораблей и судов Российской Федерации. Произведен обзор иностранного опыта и проанализированы тенденции развития российских и зарубежных корабельных и судовых ЭУ и СЭД. Рассмотрены особенности конструкции систем электродвижения кораблей и судов, показан отечественный опыт их создания. Разобраны характеристики СЭД с вентильно-индукторным гребным электродвигателем и практика их эксплуатации, а также новые разработки систем с данными типами электродвигателей большой мощности. Выполнено научно-техническое обоснование целесообразности создания СЭД с вентильно-индукторным гребным электроприводом. Монография предназначена для специалистов в области проектирования и эксплуатации корабельных (судовых) энергетических установок и электроэнергетических систем, в сфере стратегического планирования и инновационного развития. Работа также будет полезна студентам профильных вузов.
O PAPEL DOS POLIMORFISMOS GENÉTICOS NA ETIOLOGIA DA ENDOMETRIOSE
Authors: Colucci Yasmin Santos , Ruiz Cintra Mariangela Torreglosa , Trovó de Marqui Alessandra Bernadete
Published: June 2022

O objetivo desse estudo é apresentar uma atualização sobre o papel dos polimorfismos genéticos na etiologia da endometriose. Trata-se de uma pesquisa bibliográfica feita no PubMed utilizando os descritores “polymorphism and endometriosis”. Foram identificados 36 artigos e após aplicação dos critérios de inclusão foram selecionados 17 artigos para a amostra final. Os principais resultados foram: 1) cerca de 60% dos artigos foram publicados em 2019; 2) em 35,3% dos estudos o número de casos e controles investigados foi menor que 100; 3) a maioria dos trabalhos investigou de um a dois polimorfismos por gene; 4) a produção científica sobre endometriose é maior em países orientais; 5) houve heterogeneidade quanto aos periódicos onde os trabalhos foram publicados; 6) as principais técnicas para detecção de polimorfismos foi a PCR-RFLP e o PCR em tempo real, com frequências semelhantes. Em suma, os polimorfismos genéticos podem estar implicados na etiologia da endometriose.
NÍVEL DE ATIVIDADE FÍSICA DE FISIOTERAPEUTAS DE UM HOSPITAL PÚBLICO
Authors: Oliveira Maírla Rosa , De Abreu Luan Alves , Silveira Luciana Carvalho , Corrêa Krislainy de Sousa
Published: June 2022

Objetivo: avaliar o nível de atividade física dos fisioterapeutas e identificar o perfil socioeconômico destes profissionais de um hospital público de grande porte em Goiânia. Métodos:Trata-se de um estudo observacional, transversal e quantitativo realizado de abril a agosto de 2020. Foram incluídos fisioterapeutas de ambos os sexos, contratados há no mínimo seis meses, e que assinaram o termo de consentimento livre e esclarecido. Excluídos da pesquisa aqueles em férias ou licença médica no período da coleta de dados. Para avaliar o nível de atividade física utilizou-se a Questionário Internacional de Atividade Física (IPAQ), e um questionário para conhecer o perfil socioeconômico desses profissionais. As variáveis contínuas foram apresentadas como média e desvio padrão, enquanto as categóricas em frequência absoluta e relativa. Resultados: Grande parte dos indivíduos são do sexo feminino (73,5%) com maior prevalência de inativos (76%), sendo que (49,9%) cumprem carga horária maior que 30 horas semanais. Do total da amostra (61,8%) tem pelo menos especialização na sua formação profissional. Conclusão: Os fisioterapeutas do serviço público apresentam o nível de atividade física reduzido, com maior proporção classificados como inativos, segundo a OMS.
PRÁTICA CLÍNICA E BARREIRAS RELACIONADAS À MOBILIZAÇÃO PRECOCE EM UNIDADE DE TERAPIA INTENSIVA
Authors: Figueiredo Fernanda , Da Conceição Thais , Bündchen Daiana
Published: June 2022

Objetivo: caracterizar a prática clínica e identificar as barreiras relacionadas à mobilização precoce em uma Unidade de Terapia Intensiva. Método: estudo observacional analítico e prospectivo que incluiu pacientes em ventilação mecânica por mais de 24 horas. Foram coletados diariamente dados clínicos, critérios de segurança, barreiras e atividades realizadas nos atendimentos de fisioterapia. Posteriormente a amostra foi dividida de acordo com a realização de sedestação a beira do leito. Utilizou-se teste T para comparação entre grupos e para associação teste Qui-quadrado ou Exato de Fischer quando necessário. Resultados: participaram 54 indivíduos com média de idade 51,33±14,85 anos e SAPSIII médio de 63,47±13,37 pontos. A mobilização foi realizada em 1356 sessões, em sua maioria atividades passivas. Nenhuma atividade fora do leito foi realizada com pacientes em ventilação mecânica. As principais barreiras foram sedação, nível de consciência e procedimentos médicos. A não sedestação a beira do leito foi associada à ausência de critérios de segurança, que impediram a mobilização, e ocorrência de óbito. Conclusão: A mobilização foi realizada na maioria das sessões, porém poucas atividades foram realizadas fora do leito. Durante o período de ventilação mecânica nenhuma atividade foi realizada fora do leito. As barreiras mais citadas foram sedação, nível de consciência e procedimentos médicos.Palavras-chave: ventilação mecânica; deambulação precoce; fisioterapia.
N2O selectivity in industrial NH3 oxidation on Pt-gauze is determined by interaction of local flow and surface chemistry: A simulation study using mechanistic kinetics
Authors: Haas Michael , Nien Teng-Wang , Fadic Anton , Mmbaga Joe P. , Klingenberger Markus , Born Dirk , Etzold Bastian J. M. , Hayes Robert , Votsmeier Martin
Published: June 2022

Despite significant effort spent on the investigation of catalytic ammonia oxidation at the molecular scale, there is surprisingly little work that investigates the behavior of the established reaction mechanisms under industrial conditions in the presence of mass transfer limitations. This paper presents reactive flow simulations of ammonia oxidation on platinum gauzes under industrial operating conditions, combining a mechanistic description of the surface chemistry with the computation of the flow-, temperature and concentration fields around the platinum wires. Overall, the simulations yield temperature- and concentration fields, as well as integral N2O selectivity in line with industrial experience and (limited available) experimental data. In particular, the simulations predict the experimentally observed increase of the integral N2O selectivity with increasing flow velocity, decreasing wire diameter and wire-to-wire distance, and increased surface area due to surface reconstruction. The main result of the paper is that the local interaction of flow and surface chemistry leads to a variation in the local N2O selectivity across the gauze:The N2O and N2 selectivity is higher on the front side of a wire than on the rear side. A reduced N2O selectivity is observed where one wire is shadowed by another wire. Increased N2O selectivity is observed at stagnation points where upstream wires direct the flow so that it hits a downstream wire with higher velocity. These examples show that - through the flow directing effect of the upstream wires- the selectivity on an individual wire is influenced by the presence of other wires. This observation provides a mechanistic explanation for the industrial observation that optimized gauze geometries can lead to reduced N2O formation.
Second-order accurate implicit finite volume method for multidimensional modeling of PFAS transport in unsaturated porous media with variable surface tension
Authors: Li Xiaoxing , Sun Yuanyuan , Szymczak Piotr , Wu Rui
Published: June 2022

Per- and polyfluoroalkyl substances (PFASs) have become emerging contaminants of critical concern. Comprehensive understanding of the transport and fate of PFAS in the vadose-zone, a type of water-unsaturated porous media, is key to determination of the risks of the PFAS contamination in the subsurface and to the development of the effective remediation strategies. Accurate modeling of the PFAS transport in the unsaturated porous media is still a challenge due to the variable surface tension induced by the adsorption of PFAS to the air-water interfaces. In an effort to address this challenge, we propose a multidimensional modeling framework for the transient PFAS transport in the unsaturated porous media based on the second order accuracy finite volume method. In the modeling, the adsorption of PFAS to the solid surfaces and to the air-water interfaces is described by the two-domain sorption kinetics model, i.e., both the instantaneous and the rate limited PFAS adsorptions are taken into account. The diffusive and convective terms in the governing equations for the PFAS transport and the water flow are discretized by the central difference and the quadratic upstream interpolation for convective kinetics schemes, respectively. Both of these two schemes have the second order accuracy. We investigate the effects of the convergent criteria, coupling method, and variation of the surface tension on the average and the local PFAS concentration and water content in the computational domain. We find that the convergent criteria should be chosen carefully so as to get the accurate results. The differences between the different coupling methods are affected by the boundary conditions. The variation in the surface tension due to the variation of the PFAS concentration cannot be neglected. These studies not only guide the numerical schemes used in the modeling but also provide the insights into the transport of PFAS in unsaturated porous media. The multidimensional modeling framework presented in this work can be further extended to explore in detail the transport of PFAS in the vadose-zone.
Chemoenzymatic Multicomponent Synthesis of Nirmatrelvir
Authors: Preschel Hans Daniel , Otte Ruben T. , Zhuo Ying , Ruscoe Rebecca E. , Burke Ashleigh J. , Cowan Rachel , Horst Brendan , Hennig Sven , Janssen Elwin , Green Anthony , Turner Nicholas J. , Ruijter Eelco
Published: June 2022

We report a new synthesis of the Covid-19 drug nirmatrelvir featuring a highly enantioselective biocatalytic desymmetrization and a diastereoselective multicomponent reaction as the key steps. Our route avoids the use of transition metals and peptide coupling reagents, resulting in an overall highly atom-economic process.
Clinical Characteristics and Neurologic Outcomes of X-Linked Myotubular Myopathy
Authors: Woo Hyewon , Lee Seungbok , Han Ji Yeon , Kim Woo Joong , Kim Man Jin , Seong Moon-Woo , Kim Soo Yeon , Cho Anna , Lim Byung Chan , Kim Ki Joong , Chae Jong-Hee
Published: June 2022

Purpose: X-linked myotubular myopathy (XLMTM) is a rare condition of centronuclear myopathy caused by myotubularin 1 (MTM1) mutations. Patients with XLMTM show different neurodevelopmental outcomes after the neonatal period depending on age and acquired hypoxic damage. We aim to evaluate the clinical characteristics and neurodevelopmental outcomes of patients with XLMTM who were followed up at a single center. It is essential to understand the volume and conditions to prepare for being a candidate for new therapeutic strategies. Methods: Patients diagnosed with centronuclear myopathy by muscle pathology and MTM1 mutation analysis were included. We retrospectively investigated motor milestones, communication skills, and bulbar and respiratory function in the patients. The patients were categorized into two groups: with and without hypoxic insults (HI). Results: All 13 patients were severely affected by neonatal hypotonia and required respiratory support and a feeding tube during the neonatal period. The follow-up duration was 4.4 years (range, 0.3 to 8.9). In the non-HI group, developmental milestones were delayed but were slowly achieved. Some patients underwent training in oral feeding with thickened foods and weaning from ventilation. Patients with HI showed poor motor function catch-up and communication skills. Three deaths were associated with acute respiratory failure.Conclusion: Patients with XLMTM without HI can survive long-term with the slow achievement of motor milestones and bulbar and respiratory function. However, hypoxic brain damage following acute respiratory failure negatively influences their developmental potential or even lead to death. Therefore, parental education for proper respiratory management is necessary, especially for young children.
COVID 19 SALGINININ KONAKLAMA SEKTÖRÜNE FİNANSAL ETKİLERİ VE KUŞTUR KUŞADASI ANONİM ŞİRKETİ UYGULAMA ÖRNEĞİ
Authors: KOÇ Hümeyra
Published: June 2022

Çalışmada, COVID - 19 küresel salgınının Dünya’da ve Türkiye’de konaklama turizmi üzerinde finansal etkileri incelenmiştir. Bu etkilere değinilirken, alınan koruma kararlarından da kısaca bahsedilmektedir. Konaklama sektöründe bulunan şirket üzerinden de bu etkiler, salgın öncesindeki 1 yıl ve salgın sürecindeki yıllar baz alınarak mali yapı teknikleriyle incelenmiş ve yorumlanmıştır. Yapılan incelemeler sonucunda, salgının sektör üzerinde olumsuz etkilere neden olduğu, hatta salgın sürecinin başında sektörün durma noktasına geldiği, alınan tedbirlerin esnetilmesiyle beraber daha sonra sektörün toparlanmaya başladığı tespit edilmiştir. Salgın süresince de birçok işletme ve şirketin ekonomik küçülmeler yaşadığı, hatta birçoğunun faaliyetlerine devam etmekte zorlandığı bilgilerine ulaşılmıştır.
An Approach to Evaluate The Effects of Cities On Bioclimatic Conditions; The Sample of Erzurum City
Authors: ÇAĞLAK Savaş , TOY Süleyman , ESRİNGÜ Aslıhan
Published: June 2022

Kuruldukları günden buyana insanlığın gelişmesi için gerekli etkileşim ortamını kentler sağlamıştır. Kentlerin insan yaşamına olumsuz etkileri daha önce hiç ulaşmadıkları yüzey ve nüfus büyüklüğünü aştığı zaman olan Sanayi Devrimine
kadar hissedilmemiştir. Kesintisiz genişleyen ve kalabalıklaşan kent ortamında başta yoğun insan faaliyetleri nedeniyle atmosferik ortamın özellikleri bozulmuştur. Bu bozulmadan insanların etkilenme sebeplerinden biri de biyoklimatik
konfor açısından yaşanan olumsuzluklardır. Biyoklimatik konforu düşük alanlarda fiziksel ve ruhsal sağlık, enerji ve verimlilik bazlı ekonomik kayıplar ortaya çıkmaktadır. İklim değişikliğinin etkisiyle gelecekte bu kayıpların
artacağı kaçınılmazdır. Bu çalışmada, son yıllarda benimsenen ekonomi politikalarından kaynaklı toprak rantıyla hızlı yayılan Türk kentlerinden biri olan Erzurum kent merkezinde kentsel yayılmanın ve dolayısıyla yüzey artışının
insan biyoklimatik konfor şartlarına etkisinin belirlenmesine dair bir yaklaşım geliştirilmiş ve bir yıllık verilerle yaklaşım test edilmiştir. Buna göre kentsel yüzeylerin etkisiyle kır – kent arası sıcaklık stresi farkı yıl boyunca
%3,0 (kent sıcak), yaz döneminde ise %7,9’dir (kent sıcak). Kentsel planlama ve tasarım ilkelerinin uygulanması, yapılı çevre ve yeşil alan dengesinin iyi kurgulanması biyoklimatik konfor şartlarını iyileştirecektir. Bu sayede
gelecekte kentlerde daha yoğun hissedilmesi beklenen iklim değişikliğine karşı uyum daha fazla sağlanmış olacaktır.
Comparison of Conservation Methods by Moving the Cultural Heritage Remaining in the Dam Basin
Authors: Hanım HALAÇ Hicran , DOĞAN Bahar OĞUZ
Published: June 2022

Dünya genelinde sanayileşme, nüfus yoğunluğunun artması, enerji üretme, iklim krizi sonucu sulama ihtiyacı gibi sebepler suya yönelik yapılan politikaları arttırmıştır. Bu politikalar neticesinde baraj gibi büyük bayındırlık projeleri
dünyada olduğu kadar ülkemizde de doğal ve arkeolojik sit alanlarının, taşınır ve taşınmaz kültür varlıklarının yok olma riskiyle karşı karşıya kalmasına sebep olmaktadır. Türkiye’nin hızlı kalkınma süreci içerisinde olması ve
coğrafyasının baraj yapımına uygun olması sebebiyle baraj yatırımları hızlı bir şekilde artmaktadır. Bu barajların kültürel miras alanları ile çakışması önemli bir koruma sorununu beraberinde getirmektedir. Ülkemizde baraj havzasında
kalan birçok kültürel mirasa günümüze kadar koruma önlemi alınmamıştır. Ancak son yıllarda taşınır taşınmaz kültürel mirasa verilen önem ve baraj sularının oluşturabileceği hasarlar göz önüne alınarak koruma projeleri hazırlanmaya
başlanmıştır. Bu çalışmada dünyada ve ülkemizde baraj havzasında kalan kültür varlıklarının koruma yöntemlerinin neler olduğunu açıklamak ve taşıyarak koruma yöntemlerinin olumlu ve olumsuz yanları ortaya çıkarılarak farklı türdeki
koruma yöntemlerine bütüncül bir bakış açısı geliştirmek amaçlanmıştır. Bu kapsamda belirlenen anahtar kelimeler açık erişimli web sitelerinde taranmış ve 21 adet barajın verilerine ulaşılmıştır. Bu barajlardan 13 tanesinde kültürel
mirasa koruma uygulaması yapılmadan sular altında bırakılmış, 8 tanesinde ise su altında yerinde koruma ve taşıyarak koruma yöntemleri ile koruma uygulamaları yapılmıştır. Taşıyarak koruma uygulaması yapılan ve literatürde verisine
ulaşılan 5 baraj ve 13 yapı detaylı olarak incelenmiştir. Koruma yöntemlerinin yapının tekil olarak korunmasının yanı sıra kentsel hafızadaki yerinin sürdürülebilirliği açısından ele alınması gerekliliği de ortaya konulmuştur.
A Woman Composer Portrayal in the 19th Century: Fanny Mendelssohn Hensel
Authors: ARTAR Gökçe ALTAY
Published: June 2022

Bu çalışmanın içeriği 19. yüzyılda kadın bestecilerin yeri ve önemini takiben, bu yüzyılın öne çıkan Alman kadın bestecilerinden Fanny (Mendelssohn Bartholdy) Hensel’in (1805-1847) yaşamı ve yaratıcılığını ele alınmaktadır. Çağlar
boyu kendisine yüklenen toplumsal rol, inanç ve misyonlar nedeniyle arka planda kalmaya hatta kimi zaman yok olmaya mahkûm edilmiş kadın, bilim ve felsefe alanlarında olduğu gibi, sanatta da türlü mücadeleler vermiştir. Başlangıçta
eğitimden yoksun bırakılan kadın, zamanla kazandığı haklar doğrultusunda eğitim olanağını elde ettikten sonra, bestecilik sanatında da kayda değer ilerlemeler göstermiştir. 19. yüzyılda kadınların besteci olarak erkeklerle eşit
olmadıkları ve onların bu konuda doğuştan gelen eksiklikleri olduğu görüşü hakimdi. Bazı uzmanlar, kadın bestecilerin cinsiyetleri nedeniyle eksikliklerine yönelik teorileri iddia ederek tarih sahnesindeki bu sosyal mite sözde
bilim adına destek vermekteydiler. 1880’lerden itibaren, bestecilik programında kısıtlı da olsa kadınlara da yer verilmeye başlanması kadın bestecilerin sayısında bir artışla sonuçlanmıştır. Böylelikle tarihte ilk olarak bazı kadın
besteciler, erkeklerin egemen olduğu müzik sanatı alanına girmeye başladı. 19. yüzyılın en üretken kadın sanatçılarından biri olan Fanny Mendelssohn Hensel yaylı çalgılar dörtlüsü yazan ilk kadın bestecilerdendi. Sanatçı, Bach,
Beethoven ve kardeşi Felix Mendelssohn’un müziğinin bir ömür boyu savunucusu oldu. Fanny, Berlin'deki evinde düzenlediği konser dizilerinde özel dinleyicilerin gözünü kamaştıran, ender bir yetenek ve olağanüstü hafızaya sahip bir
piyanist olarak kendini gösterdi. Yüksek sınıf statüsüne ilişkin toplumsal beklentilere karşı, besteciliğin çelişkili dürtüleriyle hayatı boyunca mücadele etti ve sonunda müziğini 41 yaşında erken ölümünden sadece bir yıl önce
yayınlamaya karar verdi.
About of the “Divinity in the Time of the Prophet (Muhammad)” Named Book
Authors: AYDENİZ Hüsnü
Published: June 2022

“Hz. Peygamber Döneminde Ulûhiyyet” Adlı Eser Üzerine
Effect of Corporate Governance Structures, Political Connections, and Transfer Pricing on Tax Aggressiveness
Authors: Ardillah Kenny , Vanesa Yola
Published: June 2022

This study examines and analyzes the effect of corporate governance structures, political connections, and transfer pricing on tax aggressiveness (CETR and BTD). The theory used in this study is agency theory. The sample of this study is manufacturing companies listed on the Indonesia Stock Exchange for 2014-2019. The sampling method used in this study was purposive sampling and used multiple linear regression as the data analysis method. The results of the study using the cash effective tax rates (CETR) proxy shows that the independent board has a positive effect on tax aggressiveness, the audit committee has a negative effect on tax aggressiveness, political connections do not affect tax aggressiveness, and transfer pricing does not affect tax aggressiveness. The result of the study with a book-tax difference (BTD) proxy shows that independent commissioners do not influence tax aggressiveness, audit committees positively affect tax aggressiveness, political connections do not affect tax aggressiveness, and transfer pricing does not affect tax aggressiveness. The implication of this study reveals that the companies should follow tax regulations made by the government to do tax planning under applicable laws.
AN ANALYSIS OF ADJACENCY PAIRS IN SPEAKING CLASS AT CEC KAMPOENG PARE MATARAM 2022
Authors: Aropi Purnawan , Sahuddin  , Lestari Yuni Budi
Published: June 2022

This study aimed at finding and analyzing the types of Adjacency Pairs and their preference structures used by a teacher and students in speaking class. This study used a descriptive research method using changing observer. The sample included teacher and students of 2nd Level speaking class at Cake English Course (CEC) Kampoeng Pare Mataram. The data were collected using video recording then transcribed to be analyzed. The study shows that there are eleven types of adjacency pairs and seven of their preference structures discovered in teaching learning process. The first type is question – answer in which its preference structure is expected as preferred response and unexpected as unpreferred one. The second type is request – acceptance/rejection which acceptance is as preferred and rejection as unpreferred response of its preference structure. The next type is apology – acceptance/refusal in which both preferred and unpreferred occurred as preference structures in this type. Then, complaint – apology/denial was found in which its preference structure is preferred and unpreferred. Furthermore, invitation – acceptance in which its acceptance response is known as preferred response in preference structure. Lastly, suggestion – disagreement and offer – rejection, each of this pair has its preference structure in formed of unpreferred. However, announcement – acknowledgment, greeting – greeting, summon – answer and closing – closing adjacency pairs also occurred in this study, yet their preference structure does not exist.
The Art and Craftivism of Exhibiting Species and Habitat Loss in Natural History Museums
Authors: Wade Sarah
Published: June 2022

In recent years the presentation of anthropogenic extinction narratives in natural history museums has occurred through temporary exhibitions, curatorial and artistic interventions in permanent collections displays and public engagement events. Such work has enabled institutions to re-orientate historical collections and permanent galleries towards this pressing contemporary issue. This article examines a subset of this wider field of curatorial activity by considering how contemporary handicrafts including knitting and crochet have been displayed to engage visitors with species and habitat loss in natural history museums, situating this work within craftivist practices and the longer history of craft being mobilized for political and ethical ends. While the habitat diorama alerted audiences to disappearing species and threatened ecosystems in the twentieth century through a combination of art, science and craft, I reveal how recent exhibitions and events have reconfigured a similar interdisciplinary mix to raise awareness of species and habitat loss in the twenty-first century.
Efectividad residual de insecticidas en Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) en el cultivo de tomate
Authors: Peláez Arroyo Arturo , Vargas Hernández Mateo , Acosta Ramos Marcelo , Ayvar Serna Sergio , Díaz Nájera José Francisco , Tejeda Reyes Manuel Alejandro
Published: June 2022

Una de las principales plagas en el cultivo de tomate (Solanum lycopersicum L.) es Bemisia tabaci (Genn.), la cual transmite virus fitopatógenos responsables de daños fisiológicos severos y pérdidas de rentabilidad del cultivo. La protección de la planta contra vectores virales en las primeras semanas después del trasplante es fundamental para asegurar la producción. El experimento se realizó en invernadero y se repitió dos veces, se utilizaron plántulas de tomate cultivar Rio Grande para evaluar la efectividad residual de cinco insecticidas sintéticos, cuatro botánicos y un aceite mineral. Se evaluó la densidad de huevos de B. tabaci y el porcentaje de efectividad, a los 0, 5 y 10 días después de la aplicación (DDA) con insecticida. El tratamiento órgano-sintético con la mejor efectividad fue Sivanto®Prime (Flupyradifurone) en aplicaciones foliares y en el suelo; dentro de los productos naturales, el mejor tratamiento fue PHC® Neem® (Azadiractina) en aplicaciones foliares; ambos presentaron efectividad, de 99.96-88.47% y 65.87-43.5%, respectivamente, a los 0, 5 y 10 DDA en los dos ensayos. La información de la residualidad y la efectividad de los insecticidas evaluados contribuirá para complementar el óptimo manejo de B. tabaci.
Bridging the Knowledge Gap of Apple Growers: Transition from Conventional to Organic Production Pattern
Authors: Mohammadian Masoomeh , Niknami Mehrdad
Published: June 2022

Organic agriculture (OA) is an ecological, economic and social system that has been in the spotlight to replace and reduce the adverse consequences of conventional agriculture (CA) and achieve sustainable agriculture. The future of OA depends heavily on the knowledge of producers. Accordingly, the current research is based on the Borich model and a survey method using a questionnaire, to examine the existing knowledge and needed by Damavand gardeners to produce organic apples. Thus, using Cochran's formula, a sample of 158 gardeners were selected and interviewed by simple random sampling method. The results showed that in the planting stage, most of the respondents had very poor and weak level of knowledge, in the growing stage and the harvest the less than needed average level of knowledge to produce organic apples. However, this need decreases with increasing issues such as level of education, use of information resources, level of cultivation and work experience. Finally, based on the Borich model, priority educational issues were identified to bridge the knowledge gap in order to produce organic apples in the planting, growing and harvesting stages.
Unravelling interactive innovation through a stakeholder-associated risk analysis: evidence from two case studies in Spain
Authors: Lee SoYoung , Martin Fernandez Susana , Díaz Puente José-M.
Published: June 2022

Interactive innovation is the innovation process that is co-produced by the interaction of actors, such as farmers, land managers, researchers, policy makers and consumers. It connotes complex and socio?scientific problems that utilize participatory methodologies to bring in diverse perspectives of stakeholders, who have control over the development and decision-making process. Most failure or information absence come from insufficient communication transfer, which can result in conflicts between stakeholders, especially in projects with multi actor partnership and multidisciplinary stakeholders. Rural innovation is addressed by measuring stakeholder interactions that take place in the project. By identifying the risks in the network and the stakeholders associated to the risks, we find the underlying cause of the problem in two case studies in Spain. Results reveal that lack of communication among internal stakeholders was the main threat in both projects. Recommended action plans included establishing an effective communication strategy, establishing a well-defined terminology to avoid miscommunication among internal stakeholders and taking into account ethical and cultural differences among stakeholders to avoid mistrust. The risk analysis provides stakeholders with a holistic view over the project in knowing the location of the resources and where the problem lies. This way stakeholders can scrape out the wound.
L’actio di Odisseo e degli oratori del IV secolo nei commenti degli antichi
Authors: Manieri Alesssandra
Published: June 2022

The article reflects on the static position taken by Odysseus during the embassy to Troy described in Il. 3.312, and takes into account the points of view of ancient commentators. In particular, in the light of the debate on oratorical gestures that contrasted Aeschines and Demosthenes, we discuss the comment of Eustathius of Thessalonica who considered Odysseus as a precursor of performative attitudes that will be typical of the orators of the classical age.
Ermotimo e Marco Aurelio
Authors: Tomassi Gianluigi
Published: June 2022

Lucian loves to manipulate iconic literary types with biographical details of contemporary celebrities thereby creating an intriguing dialectical exchange between fantasy and reality. Following this pattern, the main character of theHermotimusboth descends from the immortal philosophers of comedy and reveals some traits of the ‘philosopher in purple’ Marcus Aurelius. If the highlighted similarities between the image of Hermotimus and Marcus Aurelius’ life and are convincing, it becomes possible to suggest dating the dialogue to around 176 AD.
Alessandro Boschi, Crizia tragico. Testimonianze e frammenti
Authors: Meccariello Chiara
Published: June 2022

Boschi, A. (a cura di) (2021). Crizia tragico. Testimonianze e frammenti. Tivoli: Tored. I frammenti dei tragici greci minori 2, 376 pp.
МЕХАНИЗМЫ ГЕНЕРАЦИИ И УСИЛЕНИЯ ВОЛН СЖАТИЯ ПРИ СВОБОДНОМ РАСПРОСТРАНЕНИИ ПЛАМЕНИ
Authors:   Объединенный институт высоких температур Российской академии наук, КИВЕРИН А.Д. , ЯКОВЕНКО И.С. ,   Объединенный институт высоких температур Российской академии наук
Published: June 2022

Представлены результаты расчетно-теоретического анализа механизмов генерации и усиления ударных волн в процессе свободного распространения пламени. Выявлены два базовых механизма генерации ударных волн, соответствующие линейной и нелинейной стадиям развития гидродинамической неустойчивости фронта пламени. На примере высокоактивной горючей смеси продемонстрирована роль термоакустической неустойчивости в усилении ударных волн и создании условий для перехода к детонации.
Retrospective and Prospective Analysis on Educational Leadership: Indicators of Productivity, Dispersion, and Content
Authors: GARCÍA-CARMONA Marina , MORENO GUERRERO Antonio José , RODRÍGUEZ GARCÍA Antonio Manuel
Published: June 2022

Purpose This article seeks to analyze the production, performance, impact, and content of scientific documents contained in an internationally recognized database, Web of Science, that consider Educational Leadership (EL) thesaurus (title, abstract and/or keywords). Research Methods To this end, a scientometric study was performed on a sample of 2,181 research documents that met the established inclusion criteria. A co-word analysis was also performed using Hirsch’s index (2005), as well as several bibliometric indicators, impact factors, and citation indices (h, g, hg, q2). Findings The main findings indicate that production on the topic of EL dates back to 1924, although it did not reach a significant level until 2004. There are several important points in relation to the production profile on EL that are highlighted: language, area of knowledge and institutions, and authors specializing in the subject. There are several lines of study open in the established periods, and the subjects that should be taken into account for the future are: “critical-race-theory”, “identity”, and “distributed-leadership”. Implications for Research and Practice We discuss the implications and limitations of the study and offer ways for education leaders to address new education policies, and their practical implications.