bluuebunny/crossref_metadata_2025 huggingface dataset:
Population Data Centre Profile - The Western Australian Data Linkage Branch
Authors: Hodges Steve , Eitelhuber Tom , Merchant Alexandra , Alan Janine
Published: March 2020

Established in 1995, the Western Australian Data Linkage Branch (DLB) is Australia’s longest running data linkage agency. The Western Australian Data Linkage System (WADLS) employs an enduring linkage model spanning over 60 data collections supported by internally developed and supported software and IT infrastructure. DLB has delivered, and continues to deliver, a range of significant data linkage innovations, many of which have been adopted elsewhere. A current restructure within the Western Australian Department of Health (which we will refer to as the Department of Health) will provide an improved funding model geared toward addressing issues with staff retention, capacity and customer service, as well as fostering improvements to data management, governance and availability. Research using linked data provided by DLB has been used in over 800 projects resulting in over 2350 publications and outcomes for policy development, service delivery and public health. Demand continues to grow for data linkage services and with the Department of Health’s bolstered commitment to resourcing, DLB looks forward to a future for data linkage in Western Australia that is sustainable, high quality, efficient, and safe.
IMPROVING STUDENTS’ LEARNING MOTIVATION IN READING COMPREHENSION USING RECIPROCAL TEACHING
Authors: Gunawan Helmi , Ratna Ratna
Published: March 2020

Teaching reading comprehension to the students is not easy. The teacher often finds a lot of students’ learning motivation problems from the students. The students’ problems are (1) students’ interest, (2) students’ effort, (3) self responsibility activity or persistence, (4) students’ optimal experiences; (5) reinforcement and teacher's method. One of the efforts to minimize the problems is by empowering the students in the learning process. One of the teaching techniques that can empower learners is Reciprocal Teaching Method. An action research was carried out and aimed at finding out whether Reciprocal teaching can improve the students’ learning motivation in reading comprehension in classroom when the teacher applies reciprocal teaching. Two cycles are applied. The data are taken by observing the learning process when an action is applied, by interviewing the learners involved, by giving questionnaires and by conducting interview. The finding of the research shows that Reciprocal Teaching Method can improve the students’ learning motivation in reading comprehension when it is applied.
DAMPAK TUTORIAL YOUTUBE PEER DALAM PEMBELAJARAN SISWA
Authors: Wismaningrum Yogianti Dwi Rahayu
Published: March 2020

Bagian penting dari pendidikan adalah pembelajaran siswa. Pendidikan berkualitas baik didasarkan terutama pada seberapa baik siswa memperoleh pengetahuan. Salah satu cara untuk mencapai itu adalah model pembelajaran yang menyenangkan, interaktif baik didalam kelas maupun di luar kelas dengan memanfaatkan smartphone peserta didik. Ini bisa menjadi tantangan terutama untuk pembelajaran biologi. Studi yang dilakukan dengan menerapkan “YOGI” Youtube Peer Tutoring dalam biologi untuk meningkatkan pembelajaran siswa. Kami telah mengevaluasi kinerja siswa dalam pembelajaran biologi untuk siswa dengan membandingkan dua kelompok siswa, yang pertama adalah kelompok uji di mana kami telah menyediakan siswa dengan seperangkat video dari YouTube untuk menggambarkan konsep yang berbeda seperti materi genetika dll. Untuk kelompok yang kedua di mana kami hanya menggunakan sumber daya tradisional, seperti buku teks, dalam kuliah kelas dan selebaran. Hasil penelitian telah menunjukkan bahwa Peserta didik menjadi mampu berkontribusi pada pembelajaran Biologi, Kondisi kelas menjadi interaktif, menyenangkan. Peserta didik lebih memahami penjelasan dari teman dan juga pembelajaran menjadi menyenangkan, bisa dilihat hasilnya Kompetensi peserta didik pada pembelajaran Biologi meningkat,salah satunya pada materi Genetika (pertemuan pertama 76,47% meningkat menjadi 100%). Pendidik telah menggunakan video YouTube di bidang lain seperti pembelajaran dan telah terbukti menjadi alat yang efektif untuk meningkatkan pembelajaran dan keterlibatan siswa
PENGUATAN PENDIDIKAN KARAKTER MELALUI ADAB MAKAN BERSAMA DI KELAS
Authors: Ratnawati Wahyu
Published: March 2020

Bonus demografi harus diimbangi dengan penguatan pendidikan karakter agar tercipta bangsa yang maju dan bermatabat. Pendidikan karakter membutuhkan suatu proses yaitu antara lain melalui pembiasaan. Tujuan penelitian ini yaitu mendeskripsikan menerapkan penguatan pendidikan karakter melalui adab makan bersama di kelas. Jenis penelitian kualitatif fenomenologi di SD Negeri Cemara Dua Surakarta. Teknik pengumpulan data dengan observasi, wawancara, dan dokumentasi. Teknik analisis data dengan metode interaktif. Hasil penelitian,   sekolah merupakan habitat yang tepat untuk penguatan karakter para generasi emas terutama bagi siswa. Kegiatan adab makan bersama di kelas dilaksanakan dengan tiga tahapan yaitu persiapan makan, ketika makan dan sesuadah makan. Nilai utama karakter yang dikuatkan yaitu  nilai religiousitas, nilai nasionalisme, nilai mandiri, nilai gotong-royong dan nilai intergritas. Karakter dapat tercipta karena adanya kebiasaan. Penguatan pendidikan karakter melalui adab makan bersama di kelas sangat direkomendasikan untuk di implementasikan di sekolah.
Solution of Dynamic Optimization Problems Constrained by the Fraction Penalty Method
Authors: Hartono Hartono
Published: March 2020

This article discusses the application of fractional penalty method to solve dynamic optimization problem with state constraints. The main theories supporting the use of the method are described in some theorem and corollary. The theorems give sufficient conditons for the application of the method. Therefore, if all conditions mentioned in the theorems are met then the resulted solution will converge to the analytic solution. In addition, there are some examples to support the theory. The numerical simulation shows that the accuracy of the method is quite good. Hence, this method can play a role as an alternative method for solving dynamic optimization problem with state constrints.
Малоэтажное жилье – новый инструмент развития рынка арендной недвижимости
Authors: Горбачевская Евгения
Published: March 2020

В статье рассматриваются вопросы развития такого сегмента рынка жилой недвижимости как - малоэтажное строительство. В процессе исследования проведен анализ существующих подходов и концепций реализации инвестиционно-строительных проектов в сегменте малоэтажное жилье. По результатам анализа сделан вывод, что на большинстве территорий РФ данный сегмент развивается по направлению «бизнес» и «элит». Сегменту «комфорт» отводится только 8% от общего объема реализуемых проектов. По мнению авторов, именно увеличение объемов малоэтажного строительства в сегменте «комфорт» и «эконом» класса может стать одним из основных инструментов решения жилищной проблемы в стране и достижения ориентиров, обозначенных в соответствующих стратегиях. Также в исследовании рассмотрены возможные варианты застройки пригородных территорий по плотности, и определено, что для «комфорт» и «эконом» класса актуальным может стать высокоплотное малоэтажное жилье, а основным методом строительства – крупнопанельное домостроение. В результате изучения собранной аналитической и технической информации разработаны методические рекомендации к организации массового малоэтажного строительства высокоплотного малоэтажного жилья сегментов «комфорт» и «эконом». Потенциальные преимущества рассматриваемого жилья позволяют преодолеть факторы, препятствующие развитию арендного жилья, из чего сделан вывод, что разработанные рекомендации применимы не только для проектов, предназначенных для продажи в собственность, но и сдачи в аренду семьям со средним уровнем дохода.
Formación sindical en la Argentina postdictadura: pluralismo ideológico, unidad e integración latinoamericana
Authors: Gordillo Mónica
Published: March 2020

La democracia actuó como oportunidad política para que saliera a la luz una serie de iniciativas –no suficientemente estudiadas– tendientes a fomentar la discusión y capacitación de los trabajadores en nuevos contenidos y formas de organización. El objetivo de este trabajo es recuperar algunos proyectos de formación sindical que contaron con el apoyo de redes transnacionales, buscando a su vez promover la democratización sindical. Metodológicamente el trabajo se inscribe en la reflexión sobre las formas de acción colectiva del activismo transnacional, concentrándome en una de las modalidades que adquirió durante la salida de la dictadura y los primeros años de recuperación democrática. También gira en torno a la preocupación sobre la reinserción de las tradiciones de izquierda frente a la recuperación de la democracia y, en particular, al replanteo efectuado por el peronismo revolucionario de su relación con el campo sindical. Las dimensiones trabajadas refieren a las acciones específicas desarrolladas por esas redes. La hipótesis sostiene que habrían confluido diversos emprendimientos de sectores de la izquierda peronista con otras iniciativas más novedosas como la de los Centros de Formación Sindical (CEFS) o de la propia Central Latinoamericana de Trabajadores, en torno a valores comunes. Concluyo que si bien esas experiencias fueron neutralizadas durante los años ‘80, lograron una concreción efectiva en la década siguiente.
Simulation modeling of the smart city system: The concept, methods, and cases
Authors: Makarov V.L. , Bakhtizin R.A. , Beklaryan G.L. , Akopov A.S.
Published: March 2020

Subject. The research investigates key processes of urban life and its maintenance, including food supply, infrastructure, fire security, quality and accessibility of medical services, etc. The article also discusses the creation of a system supporting the Smart City decision-making process.
Objectives. The research develops methods and tools to manage the Smart City system through system dynamics and agent-based modeling.
Methods. Using simulation modeling, namely system dynamics and agent-based modeling (supported via Powersim and AnyLogic), we evaluate how multiple guiding parameters influence crucial characteristics of the Smart City system.
Results. We devised an approach to designing the Smart City system through methods of system dynamics and agent-based modeling (supported via Powersim and AnyLogic) intended to streamline the decision making process for reasonable urban planning.
Conclusions and Relevance. We propose the consolidated architecture of the Smart City decision-making system integrating the simulation models, data storage and city monitoring subsystem. The article describes the cases of simulation models implemented via Powersim and AnyLogic to support rational urban planning. The simulation models will significantly improve the quality of urban environment, satisfy the demand for food products, provide access to healthcare services and ensure effective rescue actions in case of emergency.
The causes of poverty in Russia
Authors: Ivanchenko I.S.
Published: March 2020

Subject. This article analyzes the changes in poverty of the population of the Russian Federation. Objectives. The article aims to identify macroeconomic variables that will have the most effective impact on reducing poverty in Russia. Methods. For the study, I used the methods of logical, comparative, and statistical analyses. Results. The article presents a list of macroeconomic variables that, according to Western scholars, can influence the incomes of the poorest stratum of society and the number of unemployed in the country. The regression analysis based on the selected variables reveals those ones that have a statistically significant impact on the financial situation of the Russian poor. Relevance. The results obtained can be used by the financial market mega-regulator to make anti-poverty decisions. In addition, the models built can be useful to the executive authorities at various levels for short-term forecasting of the number of unemployed and their income in drawing up regional development plans for the areas.
Determining the discount rate when evaluating trade organizations: Some features
Authors: Grigor'eva E.A. , Buzhikeeva A.S.
Published: March 2020

Subject. This article deals with the issues of determining the market value of the trading business, taking into account a number of characteristics.
Objectives. The article aims to develop certain provisions of the methodology and practice of evaluating the business of trading organizations, namely, taking into account the additional risk of inventory feasibility when calculating the discount rate.
Methods. For the study, we used a systems approach, and the cognition, and economic and analytical research methods.
Results. The article presents a three-tiered classification of stocks and a definition of risk based on the criteria for dividing stocks by purpose, degree of implementation, and shelf life in accordance with the scale. Based on the classification, the article offers certain recommendations for determining the discount rate when evaluating trading organizations, aimed at taking into account additional risk.
Conclusions. Various evaluation procedures within the framework of traditional approaches and methods in relation to trading organizations do not take into account risk specific to this type of economic activity. The proposed methodology for calculating the discount rate for trade organizations takes into account the features of their functioning.
Dimensión afectiva en la educación: relatos escolares en una región intercultural
Authors: Espinosa Torres Iván de Jesús , Pons Bonals Leticia
Published: March 2020

Este artículo aborda relatos de la vida escolar que marcaron la existencia de un grupo diverso de actores sociales que se desenvuelven en la Región V Altos Tsotsil-Tseltal de Chiapas, México, caracterizada por la diversidad cultural y la desigualdad social. Asumiendo una perspectiva crítica y tomando como base los planteamientos de la teoría decolonial, se analiza la dimensión afectiva que se encuentra presente en las experiencias escolares. A partir de lo que denominamos phronésis metodológica y del reconocimiento de los sujetos como coinvestigadores se definieron las categorías (escuela afectiva, resiliencia y reconstrucción identitaria), las cuales surgen de los relatos escolares construidos en la región para explicar el interés de los coinvestigadores por atender las desigualdades que prevalecen en esta región intercultural. En las conclusiones se resalta la creciente importancia de la dimensión afectiva en la investigación educativa, así como su potencial para comprender los significados culturales que dan vida a una región intercultural.
Preparation of ZnO nanoflowers for surface enhance Raman scattering applications
Authors: Nguyen Viet Tuyen
Published: March 2020

Thanks to unique Raman spectra of chemical substances, a growing number of applications in environmental and biomedical fields based on Raman scattering has been developed. However, the low probability of Raman scattering hindered its potential development and thus, many different techniques were developed to enhance Raman signal. A key step of surface-enhanced Raman scattering technique is to prepare active SERS substrate from noble metals. The main enhancement mechanism is electromagnetic enhancement resulted from surface plasmon resonance. The disadvantages of nanoparticles based SERS substrates include high randomness due to self - assembly process of nanoparticles. Recently, a new kind of SERS substrates with order nanostructures of semiconductors combining with noble metals can serve as active SERS substrates, which are expected to possess high enhancement of Raman signals. In this study, ordered ZnO nanorods were first prepared by galvanic hydrothermal method and gold was sputtered on the as prepared ZnO nanomaterials to enhance Raman. Our SERS substrates exhibit promising high enhancement factors, and can detect chemical substances at concentration in nano molar range.
High efficient organic solar cell utilizing mixture of solution-processable phthalocyanine and fullerene derivative with processing additive solvent
Authors: Dao Quang-Duy
Published: March 2020

We demonstrate relatively high efficient bulk heterojunction (BHJ) organic solar cells (OSCs) utilizing a phthalocyanine derivative, 1,4,8,11,15,18,22,25-octahexylphthalocyanine (C6PcH2), and a fullerene derivative, 1-(3-methoxy-carbonyl)-propyl-1-1-phenyl-(6,6)C71 and the role of processing additive solvent on improvement of the fabricated BHJ OSCs. By adding processing additive solvent, filling factor and short-circuit current density are improved to 0.57 and 8.6 mA/cm2, respectively. As a result, the power conversion efficiency of 3.6% is achieved. Furthermore, the effects of processing additive solvent are demonstrated by taking the absorption and photoluminescence spectra of C6PcH2 and composite thin films into account.
Impact of Parallel Computing on Study of Time Evolution of a Quantum Impurity System in Response to a Quench
Authors: Hoa Nghiem Thi Minh , The Hung Dang , Minh Tuan Luong , Xuan Nui Duong , Trung Kien Nguyen Duc
Published: March 2020

In an arbitrary system subjected to a quench, or an external field that varies the system parameters, the degrees of freedom increases double in comparison to that of an isolated system. In this study, we consider the quantum impurity system subjected to a quench, and measure the corresponding time-evolution of the spectral function, which is originated from the time-resolved photoemission spectroscopy. Due to the large number of degrees of freedom, the expression of the time-dependent spectral function is twice much more complicated than that of the time-independent spectral function, and therefore the calculation is extremely time consuming. In this paper, we estimate the scale of time consumption of such calculation in comparison to that of time-independent calculation, and present our solution to the problem by using parallel computing as implementing both MPI and OpenMP to the calculation. We also discuss the possibility to exploit parallel computing with GPU in the near future, and the preliminary results of time-dependent spectral function.
Peningkatan Mutu Pendidikan Hindu Melalui Pengelolaan Pembelajaran
Authors: Widyanto I Putu
Published: March 2020

Hindu Education Institution is one of Education Institution which has responsibility in establishing and improving Hindu’s Human Resource quality to obtain competitiveness in facing globalization challenge. In the process of Hindu Education learning, still widely found the educator using Teacher-Centered Learning Approach which is makes students less actively involved in the learning process. This research aims to generate a synthesis concerning Hindu Education Learning management which can accomplish the qualification of graduate abilities which has been determined by the government. The study uses a qualitative research approach to the type of library research. The existence of Hindu education, in it’s role of engender the young Hindu generation who is ready to deal with global challenge, should be able to organize the process of debriefing with presenting education which integrate intellectuality, creativity, spirituality, and morality in its education system, and refer to the Hindu value with applying the Student-Centered Learning approach alongside learning management principal.
Flow Regime Analysis on Pressure Build-up Test Result of Z-01 Well Using Dual Porosity Reservoir Model
Authors: Hafidh Anggitya , Fathaddin Muhammad Taufiq
Published: March 2020

Flow regime analysis on the results of pressure build-up Z-01 well test was conducted to determine the type of flow that occurs in each time region section. In the early time stage there is a flow which is dominated by linear flow which is then followed by bilinear flow. At the middle time there is a radial flow where the pressure disturbance has spread towards the reservoir. In the late time flow stage is dominated by steadystate flow where the flow is affected because there is a support pressure caused by the constant pressure boundary. In the analysis of pressure build-up used to determine reservoir parameters can be used in the middle time region. This is used because the plot results between ΔP vs. log HTR (Horner Time Ratio) are straight lines which can be used to calculate reservoir parameter values such as permeability (k), formation damage factor (s). This test was analyzed using the Ecrin software and obtained a dual porosity model with a permeability value of 4.8 md, skin -3.57. From the analyzed model, it is obtained that the well fracture-finite conductivity model means that the Z-01 well has been stimulated to increase production.
Implication of the Multiphase Influx in Well Control and Circulating System
Authors: Irawan Sonny , Kinif Imros B. , Fathaddin Muhammad Taufiq , Zakaria Zulfadli B.
Published: March 2020

A multiphase flow system is commonly faced by oil and gas industries where it constituted of complex design and analysis [1].  Previous studies on the multiphase system have established a number of models including Hagerdon & Brown, Duns & Ros, Orkiszewki and Beggs & Brill [1]. Numerous studies have been carried out on the multiphase system related to production engineering [3]. However, the study on the multiphase system is found limited to be related to well control and drilling management. The multiphase system is interestingly important in well control especially during unwanted circumstances such as kick.  Flow behavior and pattern might be different from one phase system where normally only gas kick is considered during design stage of the drilling campaign. Since the multiphase kick might represent different outcome compared to one phase system, an accurate calculation of multiphase kick is desired. Therefore, the purpose of this study is to observe the impact on the multiphase kick with on the pressure drop reading and its connection with a circulating system. The study will cover on Pressure drop calculation using Beggs & Brill correlation by consolidating all the data given from various sources; Identification of flow regime of the multiphase system for the base case with several reference pressure; Sensitivity analysis including the effect of different liquid content and liquid flow rate towards the pressure drop. The expected outcomes from this study are beneficial for well control management where necessary actions to prevent blowout.
Heat dissipation of the Electrical Submersible Pump (ESP) installed in a subsea skid
Authors: Martins Jonathan Ribeiro , Ribeiro Daniel da Cunha , Pereira Fabio de Assis Ressel , Ribeiro Marcos Pellegrini , Romero Oldrich Joel
Published: March 2020

The recent development of Electrical Submersible Pump (ESP) in the skid, installed in the seabed downstream of the wellhead in an offshore oil production system, is an alternative to the conventional system with the set installed at the bottom of the producing well, facilitating interventions in case of failure. The pump is driven by an electric motor whose cooling must be efficient to ensure the continuity of its operation. The heat withdrawal is performed by the fluid produced. The purpose of this article is to understand the process of electric motor cooling to the single-phase and turbulent flow with convection heat transfer in an annular geometry, which represents the space formed between a capsule and the ESP in the Skid system motor. With this objective it is employed a Computational Fluid Dynamics (CFD) code to solve the governing equations of the turbulent heat transfer single-phase flow. The standard κ-ε model with improved wall function (Enhanced Wall Treatment) is used to closure turbulence problem. This study considered flow rates range of 2200–4200 m3/d (representing Reynolds numbers range of 27 000–133 000 approximately), Prandtl numbers 7–37, three configurations of different annular geometries, one concentric and two eccentric, together with the condition of the constant temperature on the motor surface (130 °C) and capsule (4 °C). The simulations are validated by comparing the Nusselt number in the developed region with the Gnielinski correlation. It is observed that if the constant heat flux condition were used, the motor temperature would have lower values at the beginning and larger at the end of the geometry. Therefore, the higher the Nusselt number, the greater the heat transfer, thus intensifying the cooling of the electric motor. In the eccentric geometry a momentum transfer from the lower to the upper annular region is observed, causing the Nusselt number present an angular variation. In eccentric geometries the flow develops in greater lengths, observing that the greater the eccentricity, the greater this length. Finally, for the ESP in the Skid system the use of an eccentric geometry is not adequate.
Analytical Systems in the Assessment of Library Web Sites
Authors: Udartseva Olga M.
Published: March 2020

The article considers web representations of libraries as important modern information channels through which the libraries operate in the virtual space. The author provides conceptual rationale for improving the operational efficiency of the current level of library web sites based on the data analysis of modern web analytics systems. The article studies the analytical potential of tools for optimizing web resources in the information environment, substantiates scientific and applied interest in the methods of assessment of library web site using the capabilities of analytical systems, analysed from three angles: evaluation of web resources by means of key indicators, assessment of goal achievement and evaluation by means of visual analytical maps. To solve the set tasks there were used analytical tools: Google Analytics, Yandex.Metrics. The author carried out the study to determine the goal achievement and relevance of the web site sections using the example of the State Public Scientific Technological Library of the Siberian Branch of the Russian Academy of Sciences (GPNTB SB RAS) web site. To assess the efficiency of library web resources, it is important not only to obtain statistical data from analytical tools, but also to interpret them correctly. The article presents an attempt of qualitative assessment of some key performance indicators. Collection and analysis of webometric indicators of analytical tools are of practical value, being an impetus to action — reorganization of library web resources. Based on the data analysis of Yandex.Metrics visual heat maps, the corresponding changes have been made to the web site menu. The author conducted comparative analysis of the web site traffic data before and after the changes made. The study concluded that the use of modern analytical tools in the web site management has positive dynamics for its development on the web environment. The results of the use of modern analytical tools for evaluation of library sites demonstrate the importance of their use in analysis of the efficiency of library in the virtual space, which, in turn, will have a positive impact on improving the image and competitiveness in the information and library sphere as a whole.
Dearomative Allylation of Aromatic Cyanohydrins by Palladium Catalysis: Catalyst-Enhanced Site-Selectivity
Authors: Yanagimoto Aika , Komatsuda Masaaki , Muto Kei , Yamaguchi Junichiro
Published: March 2020

A dearomative allylation of aromatic cyanohydrins with allyl borates and allyl stannanes under palladium catalysis was developed. At the initial stage of this study, the dearomative reaction (C4-substitution of the aromatics) was competing with benzyl substitution. To circumvent this issue, the use of palladium and meta-disubstituted triarylphosphine as the catalyst in a 1:1 ratio was found to enhance the site-selectivity, furnishing the desired dearomatized products. As the products possess an unsaturated nitrile moiety, further derivatizations of products such as conjugate additions and reductions were achieved.
N,N’-bis(2-(benzylthio)ethyl)malonamides: Synthesis, Electronic and Steric effects in Silver(I) Extraction and Silver(I) Binding Studies
Authors: Aderibigbe Abiodun , Clark Andrew J.
Published: March 2020

Unsubstituted and gem-diethyl substituted malonamide derivatives, bearing benzylthio arms were prepared in moderate to high yields at room temperature. It was observed that electronics effects at the 4-aryl position in the malonamide derivatives had a significant effect on the selectivity, but little effect on silver(I) extraction efficiency measured by liquid-liquid extraction experiments (with the 4-methoxy analogue proving the most selective). Increased steric hindrance near the sulfur donor had a small negative effect on silver(I) extraction efficiency, while hindrance at the methylene centre reduces selectivity. One of the malonamide derivatives prepared was found to bind to silver(I) in a 1:1 fashion suggesting a tetrahedral coordination type.
The impact of defects and crystal size on negative gas adsorption in DUT-49 analyzed by in situ 129Xe NMR spectroscopy.
Authors: Krause Simon , Reuter Florian , Ehrling Sebastian , Bon Volodymyr , Senkovska Irena , Kaskel Stefan , Brunner Eike
Published: March 2020

The origin of crystal size-dependent adsorption behavior of flexible metal-organic frameworks is increasingly studied. In this contribution, we probe the solid-fluid interactions of DUT-49 crystals of different size by in situ 129Xe NMR spectroscopy at 200 K. With decreasing size of the crystals, the average solid-fluid interactions are found to decrease reflected by a decrease in chemical shift of adsorbed xenon from 230 to 200 ppm explaining the lack of adsorption-induced transitions for smaller crystals. However, recent studies propose that these results can also originate from the presence of lattice defects. To investigate the influence of defects on the adsorption behavior of DUT-49 we synthesized a series of samples with tailored defect concentrations and characterized them by in situ 129Xe NMR. In comparison to the results obtained for crystals with different size we find pronounced changes of the adsorption behavior and influence of the chemical shift only for very high concentrations of defects, which further emphasizes the important role of particle size phenomena.
Új utak, új eszközök a munkaerőpiac jogi szabályozásában?
Authors: Rab Henriett
Published: March 2020

Könyvismertető Kun Attila: A munkajogi megfelelés ösztönzésének újszerű jogi eszközei címen, a Károli Gáspár Református Egyetem és a L’Harmattan kiadó közös gondozásában 2014-ben megjelent monográfiájáról.
Paradigmaváltás a környezeti problémák kezelésében: Az ökoszisztéma-szolgáltatás koncepció és jogi vetületei
Authors: Tóth Zsolt
Published: March 2020

A sokasodó és máig megoldatlan globális környezeti problémák kezelésére újabb és újabb megoldások, koncepciók láttak napvilágot. ezek azonban nem tettek lehetővé olyan szoros párbeszédet a különböző tudományterületek (természet- és társadalomtudományok), területhasználók, illetve döntéshozók között, hogy a döntően interdiszciplináris kihívásokra megfelelő válaszokat adjanak. A napjainkra mindinkább teret hódító ökoszisztéma-szolgáltatások koncepció éppen ezt próbálja orvosolni, azonban alkalmazásával kapcsolatban még sok a megválaszolatlan kérdés. A tudományos világ és a politikai döntéshozók közötti híd azonban felépülni látszik, ami elengedhetetlen feltétele a sikeres környezet-, illetve természetvédelemnek, és a sokat hangoztatott fenntartható fejlődés megvalósulásának is.
A sztrájkhoz való jog az Emberi Jogok Európai Bíróságának gyakorlatában
Authors: Bagdi Katalin
Published: March 2020

A sztrájkhoz való jog a munkaharc egyik formájaként a kollektív munkajog területének kiemelkedően fontos és sokat tárgyalt kérdésköre, különösen korlátozhatóságának terjedelme miatt. A munkajogviszony egyik meghatározó jellemzője, hogy a munkáltató és a munkavállaló között hierarchikus viszony alakul ki (függő munka), amelyben az utóbbi alárendelt helyzetben van. A munkavállaló személyi és gazdasági függése a munkáltatótól előbbi gazdasági és szociális kiszolgáltatottságát eredményezi, ami a felek között a polgári jogra jellemző egyensúlyi helyzetet megbontja, és így egyfajta erőbeli egyenlőtlenség alakul ki köztük. Ezen helyzetek kiegyensúlyozására szolgáló eszközök egyike a sztrájkhoz való jog, amely lényegében a munkavállaló ellenállási joga, „a kollektív önrendelkezés egyik kifejező formája”.
Values of blood copeptin level as a marker of unfavorable forecast in subarachnoid haemorrhage of the brain of atraumatic origin
Authors: Polkovnikova K.Yu.
Published: March 2020

Objective – to evaluate of diagnostic informativeness of сopeptin serum values in determining the risk of complications in patients with subarachnoid hemorrhage.Materials and methods. A prospective cohort study of 82 patients (40 men and 42 women) with spontaneous (non-traumatic) subarachnoid hemorrhage (SAH) from the age of 23 to 72 years (average age – (49,6 ±1,3) year) was conducted.Results. Complications were recorded in 31 (74.20 %) patients with a serum level of copeptin ≥ 0.605 ng/ml on the third day of the SAH, which was in 9.49 times higher (95 % CI 3.60–24.80, р ˂0.0001) than in patients with a serum level of copeptin < 0.605 ng/ml. When determining the cumulative risk of developing complications of SAH, the values ​​of positive and negative predictive values ​​of serum levels of copeptin on third day of SAH were 74.19 % and 92.20 % respectively, the accuracy of prediction (the sum of correctly classified observations) was 85.39 %.Conclusions. ROC-analysis suggests that the serum level of copeptin on third day of SAH ≥ 0.605 ng/ml is characterized by an optimal ratio of sensitivity and specificity in assessing the cumulative risk of developing such SAH complications as secondary ischemia combined with cerebral angiospasm.
Actuality of study the vascular endothelial growth factor in patients with arteriovenous malformation
Authors: Altman I.V.
Published: March 2020

Objective – to determine the role of endothelial vascular growth factor (VEGF) in the formation, progression of arteriovenous malformations (AVM), the occurrence of relapses of this disease and to justify the need to study the level of VEGF in blood plasma in patients with AVM.Materials and methods. The analysis of 15 sources of scientific and medical literature on the etio-logy and pathogenesis of AVM. Recent data of studies of the role of VEGF in the formation, progression of AVM, occurrence of relapses of this disease have been systematized. The own results of the study of the level of VEGF in blood plasma in 19 patients with AVM of different localization are presented.Results. The important role of increasing the level of VEGF in the formation, progression of AVM, both according to scientific and medical literature and according to own research, has been proved. The necessity to study the level of VEGF in blood plasma in patients with AVM in the perioperative period to improve the effectiveness of complex treatment of such patients is substantiated.Conclusions. Endothelial vascular growth factor plays an important role in the formation, progression of arteriovenous malformations. Increased level of VEGF in blood plasma in patients with AVM was noted. Increased levels of VEGF in blood plasma after surgical or endovascular treatment may cause relapses of the disease. Changes in the level of VEGF in blood plasma after surgical or endovascular treatment have not been studied at present. Studying the level of VEGF in blood plasma before and after surgical and endovascular treatment opens new possibilities for the use of drugs that block the action of VEGF as a neoadjuvant therapy for the prevention of recurrence or regression of stroke.
The experience of simultaneous endovascular occlusion of arteriovenous malformation and saccular aneurism in a parturient woman
Authors: Shchehlov D.V. , Konotopchyk S.V. , Bortnyk I.N. , Svyrydiuk O.E. , Mamonova M.Yu.
Published: March 2020

The clinical case of simultaneous endovascular bloodstream exclusion of arteriovenous malformation and saccular aneurysm in parturient woman is presented. Onyx liquid adhesive composition and monospiral aneurysm occlusion technique were used. Patient X., 31, was hospitalized to the clinic on the 10th day of the postpartum period. From the anamnesis: twice (at 20th and 27th weeks of pregnancy) patient suffered intraventricular hemorrhage due to the rupture of arteriovenous malformation in the posterior third of the corpus callosum, left lateral ventricle and left parietal lobe of the brain. After the first hemorrhage a conservative treatment tactic was determined, given the high risk of complications associated with the surgical intervention for the mother and fetus. After the second hemorrhage endovascular embolization of malformation was suggested, however, the patient and her husband refused surgery, preferring conservative therapy with subsequent surgical treatment after delivery. In addition to the malformation, according to the data of selective cerebral subtraction angiography multiple cerebral saccular aneurysms of the left Anterior Cerebral – Anterior Communicating Artery and 2 Anterior Cerebral Artery aneurysms (A2-A2, A3-A4-segments) on the right side were diagnosed. Endovascular subtotal embolization of arteriovenous malformation and occlusion of the right Anterior Cerebral Artery (A2-A3-segment) saccular aneurysm were performed during the operation. A control angiographic examination after 3 months showed a complete exclusion of these arteriovenous malformation and saccular aneurysm and disappearance of all aneurysms of the left Anterior Cerebral Artery – Anterior Communicating Artery and right Anterior Cerebral Artery (A3-A4-segment).
LİBYA İÇ SAVAŞI VE KRİZ YÖNETİMİ
Authors: GÜNEŞ Burak
Published: March 2020

Bu çalışmada,   genelde Arap
Baharı ve özelde Libya İç Savaşı konu edilmiştir. Arap Baharı sürecinin Orta
Doğu ülkeleri ve Kuzey Afrika ülkelerini derinden etkileyişi, kriz yönetimi
bağlamında değerlendirilmektedir. Bu yapılırken, modern devlet ve başarısız
devlet kavramları söz konusu tartışmaya temel oluşturmaktadır. Buna göre,
başarısız devlet olarak tanımlanan devletlerin, modern devletler sistemine
tehdit olmaktan ziyade, modern devletler sistemini yeniden üreten asli unsurlar
olduğu vurgulanmaktadır. Modern devlet iyiyi temsil ederken, başarısız devletin
kötüyü temsil etmesi tesadüf değil, bir zorunluluktur. Bu zorunluluk dış müdahalelerin
ardındaki motivasyonu da göstermektedir. Zira bir devletin başarılı olarak
kodlanabilmesi ancak ve ancak başarısız bir devletin varlığına bağlıdır.
Yukarıda belirtilen temel atıldıktan sonra, eldeki makale Libya İç Savaşını
incelemeye gayret etmektedir.

 

Çalışma Libya İç Savaşını esas itibarıyla iki
ana döneme ayırmaktadır. Buna göre ilk dönem, uluslararası müdahaleye kadar
olan ve Kaddafi’nin devrilmesi ile son bulmaktadır.  Devamla, Kaddafi sonrası iktidar ilişkilerini
içeren ve iç çatışmaların bir türlü son bulamadığı evre ise makalenin ikinci
bölümünü oluşturmaktadır. Sonuç olarak, merkezî devlet otoritesinin yıkıldığı
Libya örneğinde, iç savaşlar ya da iktidar mücadeleleri son bulmamış, krizlere
yönelik barışçıl girişimler kadük kalmıştır.  Muhtemeldir ki mevcut durum merkezî devlet
otoritesi tekrardan sağlanana kadar devam edecektir.
Clique Selection and its Effect on Paraclique Enrichment: An Experimental Study
Authors: Lu Yuping , Phillips Charles , Chesler Elissa , Langston Michael
Published: March 2020

The paraclique algorithm provides an effective means for biological data clustering. It satisfies the mathematical quest for density, while fulfilling the pragmatic need for noise abatement on real data. Given a finite, simple, edge-weighted and thresholded graph, the paraclique method first finds a maximum clique, then incorporates additional vertices in a controlled manner, and finally extracts the subgraph thereby defined. When more than one maximum clique is present, however, deciding which to employ is usually left unspecified. In practice, this frequently and quite naturally reduces to using the first maximum clique found. In this paper, maximum clique selection is studied in the context of well-annotated transcriptomic data, with ontological classification used as a proxy for cluster quality. Enrichment p-values are compared using maximum cliques chosen in a variety of ways. The most appealing and intuitive option is almost surely to start with the maximum clique having the highest average edge weight. Although there is of course no guarantee that such a strategy is any better than random choice, results derived from a large collection of experiments indicate that, in general, this approach produces a small but statistically significant improvement in overall cluster quality. Such an improvement, though modest, may be well worth pursuing in light of the time, expense and expertise often required to generate timely, high quality, high throughput biological data.
Graphical Processing Unit - Supported RNA Secondary Structure Comparison
Authors: Mete Mutlu , Arslan Abdullah
Published: March 2020

This study is part of our perpetual effort to develop improved RNA secondary structure analysis tools and databases. In this work we present a new Graphical Processing Unit (GPU)-based RNA structural analysis framework that supports fast multiple RNA secondary structure comparison for very large databases. A search-based secondary structure comparison algorithm deployed in RNASSAC website helps bioinformaticians find common RNA substructures from the underlying database. The algorithm performs two levels of binary searches on the database. Its time requirement is affected by the database size. Experiments on the RNASSAC website show that the algorithm takes seconds for a database of 4,666 RNAs. For example, it takes about 4.4 sec for comparing 25 RNAs from this database. In another case, when many non-overlapping common substructures are desired, a heuristic approach requires as long as 85 sec in comparing 40 RNAs from the same database. The comparisons by this sequential algorithm takes at least 50% more time when RNAs are compared from the database of several millions of RNAs. The most recently curated databases already have millions of RNA secondary structures. The improvement in run-time performance of comparison algorithms is necessary. This study present a GPU-based RNA substructure comparison algorithm with which running time for multiple RNA secondary structures remains feasible for large databases. Our new parallel algorithm is 12 times faster than the CPU version (sequential) comparison algorithm of the RNASSAC website. The response time significantly reduces towards development of a realtime RNA comparison web service for bioinformatics community.
Experimenting with Theory Instantiation in Vampire
Authors: Riener Martin
Published: March 2020

Theory instantiation tackles the problem of theory reasoning with quantifiers in Vam- pire using an SMT solver. In contrast to AVATAR modulo theories it works locally by instantiating a clause such that its pure theory part becomes inconsistent and can be deleted. We report on the challenges when adding instantiation for the theory of arrays.
From Unsupervised Multi-Instance Learning to Identification of Near-Native Protein Structures
Authors: Alam Fardina , Shehu Amarda
Published: March 2020

A major challenge in computational biology regards recognizing one or more biologically- active/native tertiary protein structures among thousands of physically-realistic structures generated via template-free protein structure prediction algorithms. Clustering structures based on structural similarity remains a popular approach. However, clustering orga- nizes structures into groups and does not directly provide a mechanism to select individual structures for prediction. In this paper, we provide a few algorithms for this selection prob- lem. We approach the problem under unsupervised multi-instance learning and address it in three stages, first organizing structures into bags, identifying relevant bags, and then drawing individual structures/instances from these bags. We present both non-parametric and parametric algorithms for drawing individual instances. In the latter, parameters are trained over training data and evaluated over testing data via rigorous metrics.
Exploring Deep Neural Network Architectures: A Case Study on Improving Antimicrobial Peptide Recognition
Authors: Dua Manpriya , Barbara Daniel , Shehu Amarda
Published: March 2020

With antibiotic resistance on the rise, health organizations are urging for the design of new drug templates. Naturally-occurring antimicrobial peptides (AMPs) promise to serve as such templates, as they show lower likelihood for bacteria to form resistance. This has motivated wet and dry laboratories to seek novel AMPs. The sequence diversity of these peptides, however, renders systematic wet-lab screening studies either infeasible or too narrow in scope. Dry laboratories have focused instead on machine learning approaches. In this paper, we explore various deep neural network architectures aimed at improving antimicrobial peptide recognition. Our enquiry results in several architectures with com- parable or better performance than existing, state-of-the-art discriminative models.
Visualizing Omics Data from Spaceflight Samples using the NASA GeneLab Platform
Authors: Berrios Daniel , Weitz Eric , Grigorev Kirill , Costes Sylvain , Gebre Samrawit , Beheshti Afshin
Published: March 2020

NASA’s GeneLab platform is the first omics database and platform limited to studies related to space flight. This platform provides the scientific community a valuable resource for exploring, evaluating, and discovering hypotheses of space biology. In the platform we offer users multiple tools to explore GeneLab data including: a comprehensive, well-annotated data repository for all space related omics data, omics data analysis tools, space environmental metadata, and differential gene expression visualization tools. Here we focus on the latter, and how these tools can be utilized to explore scientific questions related to space biology. Spaceflight is known to create many health risks in astronauts due to both microgravity and space radiation exposure. Current research is focused on the underlying biological mechanisms behind these health risks and potential countermeasures to mitigate these health risks. One specific health risk is related to increased liver damage during exposure to the space environment (Beheshti et al, Scientific Reports, 2019). Longer exposure to the space environment appears to cause increased lipid accumulation and transcriptomic analysis suggests pathways and genes related to liver disease (i.e. PPARα, Insulin or INS, and Glucagon or GCG) can be activated. We use this scenario to demonstrate how GeneLab’s platform and visualization capabilities can be utilized to quickly reveal this process in GeneLab platform data. Lastly, we discuss some issues and best practices for implementing similar, public- platform visualization tools.