bluuebunny/crossref_metadata_2025 huggingface dataset:
INVESTİGATİON OF THE ANTİMİCROBİAL EFFECT OF COMPOSİTİONS OF ESSENTİAL OİLS OBTAİNED FROM AROMATİC PLANTS WİTH WHİTE NAPHTHALENE OİL AND MALİC ACİD
Authors:   1Azerbaijan Medical University, Department of Medical Microbiology and Immunology, Gadirova H.A. , Suleymanova T.H. ,   1Azerbaijan Medical University, Department of Medical Microbiology and Immunology, Azizova A.N. ,   Department of Microbiology of SR Institute of Medical Prophylaxis
Published: February 2024

The article presents the results of studying the antimicrobial properties of some essential oils (essential oils of mountain mint, wild mint and Stachys officinalis) in free form, as well as in dilutions with purified resinless white naphthalan oil and their combinations with various substances. As a result of the research, it was found that although the essential oils of mountain mint, wild mint and Stachys officinalis, as well as purified white naftalan oil, individually had a moderate to strong antimicrobial effect, in joint combinations they lost their activity. Adding oil of saturia, limonene, menthol and malic acid to the essential oil of field mint and Stachys officinalis, on the contrary, led to a significant increase in their antimicrobial properties. These compositions have been found to have very strong antibacterial and antifungal properties.
LOW-DOSE THYMOQUINONE: A CHANCE FOR PREVENTIVE TREATMENT BE-FOREHEPATIC ENCEPHALOPATHY DEVELOPS: AN EXPERIMENTAL RAT STUDY
Authors:   Department of Pharmacology, Faculty of Medicine, University of Ataturk, Bekmez Huseyin , Bayraktar Mustafa ,   Department of Family Medicine, Faculty of Medicine, University of Ataturk, Aliyeva Kubra ,   Department of Pharmaceutical Technology and Management, Faculty of Pharmacy, Azerbaijan Medical University, Albayrak Abdulmecit ,   Department of Pharmacology, Faculty of Medicine, University of Ataturk
Published: February 2024

Objective: Thymoquinone (Nigella sativa), one of the popular phytotherapy bioactive sub-stances, is an antioxidant and anti-inflammatory substance with known hepatoprotective activity. In this study, we investigated whether thymoquinone has preventive effects on the development of hepatic encephalopathy in rats with hepatic encephalopathy model at two different doses. Methods: Healthy albino Spraque-dawley rats were randomized into 4 different groups: healthy negative control group, positive control group in which hepatic encephalopathy was in-duced by intraperitoneal thioacetamide 200 mg/kg, Thymoquinone 10 mg/kg and Thymoqui-none 20 mg/kg treatment groups. Thymoquinone was administered to the thymoquinone treated groups by gavage for 14 days, and then a hepatic encephalopathy model was induced with 200 mg/kg thioacetamide for three days. All rats were subjected to locomotor activity tests twice, once at the beginning and once at the end, and serum ammonium levels were measured and compared to determine whether the hepatic encephalopathy model occurred. Results: While the baseline locomotor activity tests of the groups included in the study were not statistically different, the final locomotor activity tests were found to be statistically signifi-cantly different (p<0.05). In the post-hoc analysis, it was found that Thymoquinone 10 mg/kg group was statistically significantly different (p<0.05) in most of the locomotor activity tests from the positive control group in which hepatic encephalopathy model was created, and on the contrary, it had similar results to the healthy negative control group (p>0.05). Serum ammonium levels were lower in both thymoquinone groups compared to the positive control group, but not statistically differed (p>0.05). Conclusion: Low dose Thymoquinone (10 mg/kg) group had similar results with the healthy group in both locomotor activity tests and serum ammonium levels. Thus, low dose Thymoqui-none offers a promising treatment opportunity within the scope of preventive medicine for indi-viduals at high risk of developing hepatic encephalopathy.
DEVELOPMENT OF TECHNOLOGY FOR COSMETIC GELS BASED ON SOME POL-YMER CARRIERS AND THEIR STANDARDIZATION
Authors:   Department of Pharmaceutical Technology and Management, Azerbaijan Medical University, Mamedova Zuleikha Ch. , Mamedova Afsana E. ,   Department of Pharmaceutical Technology and Management, Azerbaijan Medical University, Mamedov Fuad I. ,   Department of Pharmaceutical Chemistry, Azerbaijan Medical University
Published: February 2024

The purpose of the research work was to develop the technology of cosmetic gels from the phytocomposition extract, based on some polymer carriers and their standardization. Based on an extract obtained by maceration using 70% ethyl alcohol as a solvent, from a herbal collection consisting of rose hips, calendula flowers and rosemary herb (3.5:3.5:3), a technology has been developed for producing gels based on three different polymers (Na-alginate (composition I), PEQ 4000 (composition II) and Na-KMS (composition I). Some physical and physicochemical parameters of the obtained gels were determined (appearance, color, smell, homogeneity, asso-ciated impurities, pH, exfoliation, thermal and colloidal stability, mechanical contamination and aggregation stability). A spectrophotometric quantitative determination of the amount of flavo-noids by rutoside in the prepared gels was carried out.
Phytochemical, cytotoxic, antileishmania and antimicrobial potentials of Rhodes grass (Chloris gayana Kunth)
Authors: Oliveira Maria José Cândido de , Reis Cíntia Régis da Silva , Lima Junior Paulo Sousa , Sousa Jonas Nascimento de , Costa Sobrinho-Júnior Enoque Pereira , Alves Michel Muálem de Moraes , Carvalho Fernando Aécio de Amorim , Citó Antonia Maria das Graças Lopes , Santos Carlos Alberto Garcia , Barreto Humberto Medeiros , Costa Danielly Albuquerque da , Arcanjo Daniel Dias Rufino
Published: February 2024

The present study aimed to analyze the cytotoxic and antimicrobial activity of the plant Chloris gayana Kunth (Poaceae) proceeding from the ethanol extract, taking into consideration its major secondary metabolites, such as alkaloids, triterpenes, steroids, flavonoids, and tannins. The ethanol extract showed no antimicrobial activity against Staphylococcus aureus, Escherichia coli and Candida krusei. However, the ethanol extract was able to potentiate the activity of amikacin against a strain of S. aureus MRSA (methicillin resistant S. aureus), suggesting a possible application of the extract itself or its isolated phytochemicals, as adjuvants of amikacin in the treatment of infections caused by MRSA strains resistant to this antibiotic. Potential antileishmanial activity was observed, but further research on the isolated action of these metabolites is needed.
Etyka informacji
Authors: Stefanowicz Bogdan
Published: February 2024

The article discusses selected aspects of information ethics in the context of some information processes. Information functions as well as their quality characteristics, important from the view point of the ethics, are presented, too. A special attention is paid to information interpretation. Information exchange as well as a people behaviour by collection, using and communication of information are very important questions. The significance of the information process creation as well as their impact on conditions necessary to maintenance true and reliable information are stressed in the article.
Wspomaganie innowacji finansowanych przez przedsiębiorstwa w Unii Europejskiej
Authors: Baruk Jerzy
Published: February 2024

The author analyses the empirical research results of the surveys conducted in EU enterprises concerneiry innovation expenditures in 2006–2008. This analysis was conducted from a point of view of EU Member States as well as enterprise segments. Purchase of new or significantly improved machinery, equipment and software was the most common form of the innovative investment in case of the surveyed companies in 2006–2008. Purchase of domestic and foreign patents as well as inventions and know-how was significantly less common. The R+D activity, as important source of knowledge, were used on a relatively lower level.
Ceny usług związanych z użytkowaniem mieszkań przez właścicieli we wskaźniku cen towarów i usług konsumpcyjnych
Authors: Leszczyńska Agnieszka
Published: February 2024

The Consumer Price Index (CPI) is a main synthetic measure of changes in living expenses of an average household. In order to fulfill this role, the structure of the index should correspond with the actual consumption pattern of households. The housing service consumed by the homeowners (owner occupied housing – OOH), a very important component of consumption, is currently omitted in the Polish CPI. The article presents a summary of the ongoing discussion on including the housing service costs in the CPI. Some theoretical arguments are followed by the description of the most frequently used ways to calculate the cost of OOH. The paper concludes with an international review of national price indices with the OOH costs inclusion.
Wykorzystanie metody DEA do oceny efektywności w usługach sektora publicznego
Authors: Kozuń-Cieślak Grażyna
Published: February 2024

The article discusses The Data Envelopment Analysis (DEA) Method which is used to estimate expenditure efficiency of public sector units. The paper includes a review of a foreign literature, where are described trials of the method using in international as well as regional and local scales. The DEA Method is discussed in relation to public sector expenditures, such as an activity efficiency of the health service as well as education, mitigating poverty effects and infrastructure developing. The accuracy of the method to estimate the efficiency of public sector units results from its origin. It has been formed as a work result on estimation of activities, which cannot be estimated by traditional methods. The article describes studies which have formulated the basic DEA-CCR (Charnes, Cooper, Rhodes) method 30 years ago. The DEA methodological bases as well as its attributes are discussed in the article. The paper is ended with an estimation of the public expenditures efficiency for health care in the new EU Member States prepared by the described method.
Analisis Strategi Pemilihan Lokasi Usaha UMKM Surabaya Ditengah Perubahan Perilaku Konsumen Ke E-Commerce
Authors: Rachma Amalia Fadilla , Sulistyowati Eni , Siswanto Arif , Andriyanto Ronny , Suindyah Sayekti
Published: February 2024

Pandemi COVID-19 menyebabkan perubahan dalam segala aspek kehidupan terutama bisnis. Pelaku Usaha Mikro, Kecil dan Menengah (UMKM) merasakan dampak akibat adanya Pemberlakuan Pembatasan Kerumunan Masyarakat (PPKM) yang menyebabkan kegiatan operasional bisnis ikut terganggu. Adanya PPKM menyebabkan timbulnya perubahan perilaku konsumen dari yang sebelumnya jarang melakukan pembelanjaan online menjadi sering. UMKM memiliki banyak tantangan dalam menjalankan operasionalnya baik dari segi finansial maupun cakupan wilayah usaha apalagi setelah adanya perubahan perilaku konsumen yang beralih ke belanja di e-commerce. Tujuan penelitian ini untuk mengetahui strategi pemilihan lokasi usaha UMKM Surabaya ditengah perubahan perilaku konsumen E-Commerce. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif, teknik pengumpulan data yang digunakan dalam penelitian ini yaitu observasi, wawancara dan studi kepustakaan. Hasil penelitian ini menunjukkan bahwa pemilihan lokasi usaha yang tepat merupakan solusi bagi pebisnis UMKM yang masih belum ingin mendigitalisasi usahanya.
Polynominativity of geographical objects in the linguocultural context
Authors: Bobrova Maria V.
Published: February 2024

The article attempts to analyze the linguocultural factors contributing to the phenome­non of polynominativity—multiple names for a single object. This investi­gation employs top­onyms as a case study. The exploration delves into several key factors that give rise to poly­onyms: 1) linguosociocultural factors: these factors play a pivotal role in shaping subsystems of names, encompassing both official and unof­ficial, widely used and niche terms, as well as neutral and connotatively charged expressions. 2) linguogeocultural factors: they contribute to the differentiation of objects based on culturally significant oppositions such as ‘near-far’, ‘left-right’, and subsequently transmit binary characteristics like ‘own-alien’,’ ‘good-bad’, among others. 3) linguoethnocultural factors: these factors elucidate the intricacies of the in­teraction and mutual influence of onomastic systems from different ethnic groups coexisting within the same geographical space. 4) linguopragmatic factors: these factors drive the multi­plication of onomastic units and subsystems for utilitarian purposes, including cultural con­siderations. 5) linguocognitive factors: they lead to the emergence of ‘double’ names that mir­ror individual or collective features of a particular worldview model. It is evident that these factors interact dynamically within specific historical, social, and cultural contexts. The study of the intricate interplay between these elements holds promise, and advancements in onomas­tic ethnolinguistics, coupled with developments in computational linguistics, are par­ticularly noteworthy. Despite progress, researchers tackling this thematic area are confronted with numerous unresolved questions.
PROMISING METHODS FOR DETECTING SUBMARINE GROUNDWATER DISCHARGE IN THE BALTIC SEA AND EXPERIENCE OF THEIR APPLICATION
Authors:   Immanuel Kant Baltic Federal University, Mikhnevich Galina S. , Yakimova Ekaterina A. ,   Immanuel Kant Baltic Federal University
Published: February 2024

Submarine discharge of groundwater (SDGW) is a hydrological process that typically occurs in coastal areas and is defined as the underwater inflow of fresh and brackish ground­water from the continent to the sea. The discharge of waters with a composition sharply differ­ent from seawater leads to the formation of hydrochemical anomalies in the near-bottom hori­zon and alters the composition of bottom sediments. Under different regional conditions, dis­charge can occur as a focused flow through cracks in karst and fissured rocks, as a diffuse flow in loose deposits, or through the recirculation of seawater in bottom deposits. Therefore, it is essential to consider local geological and hydrogeological conditions, as they can significantly influence the character and distribution of groundwater and, consequently, the possibility of submarine discharge and the likelihood of its detection. Despite the ubiquity of the SDGW process in the continental shelf zone, practical detection is often a challenging task. The aim of this study is to identify approaches that best allow for documenting the phenomenon of sub­marine discharge of groundwater in the southeast part of the Baltic Sea. Detecting submarine groundwater discharge in the Baltic Sea is crucial for understanding the processes in the wa­ter body and evaluating the ecological situation. The study examines various methods for detecting SDGW: computational-analytical, geophysical, radioisotopic, chemical, and biologi­cal. The expe­rience of their application in the southeastern Baltic Sea is characterized, allow­ing for the identi­fication of areas where submarine discharge of groundwater from Jurassic and Cretaceous hori­zons occurs. The conclusion is drawn that for effective detection of sub­marine discharge foci, a comprehensive approach involving various research methods is neces­sary.
TRAINING OF SCIENTIFIC PERSONNEL IN THE HISTORY OF RUSSIAN LAW IN THE RUSSIA ABROAD (1920—1930s): HARBIN AND PRAGUE
Authors:   Bryansk State Academician I.G. Petrovski University, Mikhalchenko Sergey I. , Tkachenko Elena V. ,   Bryansk State Academician I.G. Petrovski University
Published: February 2024

The article examines the system of training academic personnel in the history of the Russian state and law at the law faculties of the Russian Abroad in Harbin and Prague in the 1920—1930s. The main sources include case-related documentation from the archives of Russian institutions (State Archive of the Russian Federation, Archive of the Russian Academy of Sciences, State Archive of the Rostov Region), memoirs, and publications by contemporary emigrant scholars. It is argued that the training system for this discipline did not have the opportunity to develop in the pre-revolutionary Russian Empire, as the academic degree category “History of Russian Law” was only introduced in 1915. Consequently, the preparation of students at the department for professorial candidacy had a largely innovative character in the higher education institutions of the Russian emigration. Considerable attention was paid to the training of specialists in the history of Russian law at both faculties. However, the shortage of well-established academic staff in Harbin necessitated sending students to European research centers. In Prague, an independent training system for this discipline emerged. Nevertheless, the outcome proved to be unproductive—with only one master’s and one doctoral dissertation in the field of the history of Russian law within the framework of the pre-revolutionary Russian tradition defended (by M. V. Shakhmatov).
Royal Society OA pricing model changed
Authors:   Europe PMC Team
Published: February 2024

The Royal Society have announced a change in the pricing structure for its author-pays, open access model, known as EXiS Open Choice. Responding to author feedback, EXiS fees will now be based on a per-article rate, rather than a per-page rate.
Szülői attitűdök, magatartásformák a tévéhasználatra vonatkozóan egy székelyföldi településen
Authors:   Debreceni Egyetem, Magyarország/Marosszentgyörgy, Románia, Molnár Orsolya
Published: February 2024

In my study, I analyse parental attitudes towards children's TV watching in a suburban settlement. I analyze two components of parental attitudes. In my research, I conducted semi-structured interviews with mothers from Sângeorgiu de Mureș who have children in grades 5-8 and attend an educational institution in the settlement. The interviews were structured around three main themes: how parents think about their children's time in front of the television, what kind of regulation they use when it comes to deciding about their children's time in front of the television and when it comes to deciding about content consumption. In my study, I use the resulting text data to analyse statements about children's television use and identify parental attitudes.
A tanítók tapasztalatai az iskolai bántalmazásról
Authors:   Debreceni Egyetem, Magyarország/ Csíkszereda, Románia, Vaszi Emőke
Published: February 2024

The present study examines the perceptions and experiences of teachers in schools in Bazinul Ciucului regarding bullying in schools. I chose semi-structured interviews as the research method. The statements extracted from the text corpus of the interviews were divided into two themes: (1) analysis of statements on the occurrence of bullying and (2) analysis of statements on the manifestations of bullying (social, verbal and physical).
Fiatalok, vidék, vidékkép
Authors:   Sapientia Erdélyi Magyar Tudományegyetem, Csíkszeredai kar, Okos Zsuzsanna
Published: February 2024

The study presents the results of a survey conducted among young people in secondary school in Miercurea-Ciuc, which investigated young people's attitudes towards rurality. The results of the data collection are presented in four thematic areas: opinions on the countryside, arguments in favour of rural lifestyle, barriers to choosing a rural lifestyle, and the target group's perception of what factors of the area under study would be valuable for a foreigner.
A szegénység csökkentésére irányuló szakpolitikák konceptuális megközelítései
Authors:   Debreceni Egyetem, Magyarország/Szováta, Románia, Néma Judit-Eszter
Published: February 2024

The Outlook paper presents Panica's 2023 study on the changing relationship between conceptual approaches to development and poverty reduction policies.
In contemporary social policy discourses, the legitimacy of the institution of the 'state' is increasingly subject to critique. Although the state, including welfare systems, played a significant role in the modern civilisation process in Western Europe, the cultural-civilisational 'development' of society in Central and Eastern Europe was different from that in the West. Daniela Panica's study, presented below, was conceived with the intention of understanding the ideologies that aspired to welfare statehood in Romania. She argues that to model these processes, it is necessary to have a comprehensive understanding of the eras of social policy, which can be best captured through chronological changes in the poverty reduction methods used.
Violência Infantil no Brasil de 2011 a 2014: Perfil do Suspeito
Authors: Haddad Kamila , Agudo Oliveira Benito Linconl
Published: February 2024

Trata-se de um estudo retrospectivo, comparativo e com abordagem quantitativa, que analisou a frequência de registros de denúncias notificadas pelo Programa Disque 100, de violência sexual contra crianças, analisando o perfil do acusado, no Brasil entre os anos de 2011 a 2014. Os dados foram solicitados junto à Secretaria Nacional de Direitos Humanos (SNDH) da Presidência da República (PR). Foram também utilizados subsídios adquiridos na BVS, LILACS e SCIELO. Por meio do presente estudo foi possível perceber um universo total de 41.842 registros, sendo que a maior frequência dos agressores identificados eram do sexo masculino com 58,90% (n=24.652), de raça/cor parda 46,05% (n=9.964) e faixa etária entre 31 a 40 anos com 19,90% (n=8.315). O estudo demonstrou ainda uma redução na frequência de registros de violência sexual contra crianças no Brasil no recorte histórico e geográfico analisados.
Policiamento Ostensivo e Policiamento Velado: Integração e Assuntos Correlatos
Authors: Fabrício de Andrade Raymundo Fabrício
Published: February 2024

Situada entre as atividades de prevenção e investigação criminal, a atividade repressiva é a mais evidente das atividades policiais no que tange principalmente à solução dos conflitos delituosos. Essa atividade reside no ato de chamamento pela população da ação policial, a ser executada pela Polícia Militar, quando o cidadão a convoca para a intervenção diante do delito em cometimento, é dizer, nas fases da execução e consumação delituosa - a repressão imediata. No intuito de efetuar esta atividade com um nível maior de eficiência, busca-se por meio de um serviço já existente nas Polícias Militares – o policiamento velado – implementar a integração entre a atuação policial ostensiva e o suporte descaracterizado. Objetiva ainda, a excelência no atendimento à população, frente à evolução constante dos métodos empregados pela criminalidade, multiplicando-se assim, as chances de, em não havendo a possibilidade de prevenção, que haja a prisão em flagrante após o cometimento do delito.
Socialization of Digital Marketing and Fintech Literacy for Micro & Small Businesses in Samarinda City
Authors: Adhimursandi Doddy , Azis Musdalifah , Heksarini Ariesta , Asnawati Asnawati
Published: February 2024

Micro, Small, and Medium Enterprises (MSMEs) are a vital component of the community economy, and their success is crucial for economic growth. Despite the increasing digitalization of the world, many MSMEs continue to rely on traditional business methods, such as using printed money. This presents a challenge for MSMEs to keep pace with changing times and compete in the digital era. To overcome this obstacle, it is imperative to provide education and direct assistance to MSME partners on how to apply digital marketing and financial technology. This can be accomplished through socialization programs that educate partners about digital marketing and fintech, as well as provide them with the necessary steps to register in the Gojek application as a marketplace tool. The mentoring stage is also critical for ensuring that partners can apply the provided technology and utilize online platforms to facilitate sales. By providing partners with the necessary skills and knowledge, MSMEs can increase their sales efficiency and contribute to economic growth. In summary, the support and assistance provided to MSMEs in adopting digital marketing and financial technology are necessary to ensure their survival and success in the digital era. MSMEs can increase their sales efficiency and contribute to economic growth through the right education and mentoring.
SALUTE E PREVENZIONE ORALE CORRELATA ALL’ ALIMENTAZIONE”
Authors:   Universita Federico II, Napoli, Italia, Bellia Loredana , Ruggiero Roberta ,   Universita Federico II, Napoli, Italia, Lo Spinuso Martina
Published: February 2024

Lo scopo di questo studio è stato quello di mettere in risalto la correlazione che esiste fra igiene orale e patologie del cavo orale.Il tutto va di pari passo in una sinergia fatta di attenzioni da parte del paziente nonché, competenze e tecniche che l’igienista dovrà adottare nelle varie circostanze e a seconda delle problematiche rilevate. La sinergia esistente tra salute orale, salute sistemica e alimentazione è un processo dinamico che dovrebbe essere alla base di ogni disciplina medica per l’attuazione di misure preventive per la salute pubblica. Le patologie del cavo orale, sono associate in molti casi a scarsa igiene, ad una alimentazione non corretta, nonché a stili di vita non propriamente salutari che finiscono con l’influenzare l’aspetto relazionale e di autostima dell’individuo. L’educazione alla salute orale richiede l’insegnamento di una adeguata igiene del cavo orale, ma soprattutto l’abitudine ad un corretto stile di vita, quindi, l’educazione ad una sana alimentazione che inizia fin da piccoli e viene coltivata per tutta la vita. Quelle che per un odontoiatra o igienista dentale possono essere informazioni scontate, perché acquisite durante gli anni di studio e di esperienza, possono risultare completamente estranee ai pazienti che non sono in grado di comprendere quanto i diversi tipi di alimentazione possano influire sul nostro benessere e come a volte, il cibo, può essere un alleato per tutelare la salute orale. Per assicurarsi una eccellente salute del nostro cavo orale, difatti, non basta una corretta e quotidiana igiene accompagnata da controlli professionali. L’igiene orale, infatti, è spesso molto trascurata a causa di una scorretta alimentazione, che non riguarda solo il tipo di alimenti che si assumono ma anche la frequenza della loro assunzione.
Comparison of ECL, ELISA and ELFA immunoassays
Authors:   University “Ismail Qemali”, Vlora, Albania, Laze Blerta , Mitre Anila
Published: February 2024

The aim of these study was the evaluation of electrochemiluminescence assay (ECL), enzyme-linked immunosorbent assay (ELISA) and enzyme-linked fluorescent assay (ELFA), for an early diagnosis of Cytomegalovirus infections in pregnant women. In medical diagnostics, it is necessary to determine the most sensitive techniques for the detection of this pathogen, due to it’s multiple fetal infections during pregnancy. The ECL technique resulted with the highest sensitivity and specificity values. However, for diagnostic purposes, the results should always be assessed in conjunction with the patient’s medical history and other clinical examinations.
RIGHT CORONARY ARTERY PERCUTANEOUS CORONARY INTERVENTION IN A PATIENT WITH ANOMALOUS ORIGIN OF LEFT MAIN FROM RIGHT CORONARY SINUS – CASE REPORT”
Authors:   Cardiology Department, University Hospital Center ", Gishto Taulant ,   Mother Teresa",   ,Tirana,Albania Tirana, Albania, Dragoshi Arlind ,   Cardiology Department, University Hospital Center "Mother Teresa", Tirana, Albania Tirana, Albania
Published: February 2024

A 63-year-old male is hospitalized during an episode of NSTEMI and therefore he underwent Coronary Angiography which revealed Two-Vessel coronary artery disease and anomalous origin of Left Main Artery. Left Main Artery and Right Coronary Artery did both originate from right coronary sinus, but with separate ostia. The patient underwent revascularization of Right Coronary Artery with balloon angioplasty and drug eluting stents. The case report is made at the University Hospital Center “Mother Tereza”, Tirana Albania.
THE IMPACT OF TRADE OPENNESS ON POVERTY REDUCTION: EVIDENCE FROM WESTERN BALKANS
Authors:   Economist, “BB group Construction”, Tirana, Babasi Halisa
Published: February 2024

Zhdukja e varfërisë në të gjitha format e saj është një nga sfidat më të mëdha me të cilat është përballur bota gjatë dekadave të fundit. Megjithëse shumica e ekonomistëve pajtohen se në terma afatgjatë, ekonomitë që janë të angazhuara në tregtinë ndërkombëtare performojnë më mirë në total sesa ato të mbyllura, ndikimi që ka hapja e tregtisë në reduktimin e varfërisë është i paqartë. Qëllimi i këtij studimi është të ekzaminojë ndikimin e hapjes tregtare në uljen e varfërisë, me evidencë në vendet e Ballkanit Perëndimor, duke përdorur të dhënat vjetore për periudhën 2000-2019. Metodologjia e përdorur përfshin statistikat përshkruese dhe analizën e regresionit të shumëfishtë duke përdorur metodën Panel Fully Modified Least Squares. Indeksi i zhvillimit njerëzor (HDI) merret si variabël i varur, i cili shërben si një tregues i varfërisë. Të dhënat e përdorura në këtë studim janë mbledhur nga Banka Botërore dhe Kombet e Bashkuara. Risia e këtij studimi qëndron tek fakti se është ndër të paktat iniciativa që tenton të ekzaminojë drejtpërdrejt ndikimin e hapjes tregtare në uljen e varfërisë në këtë grup vendesh, për periudhën e dy dekadave të fundit nëpërmjet një metode të modifikuar plotësisht. Rezultatet mund të shërbejnë dhe mund të merren parasysh gjatë zbatimit të analizave të ngjashme ekonometrike në kërkimet e ardhshme.
INDEKSIMI NE CROSS REFF, INTEGRITET, ZHVILLIM INSTITUCIONAL DHE PROFESSIONAL
Authors:   University College Reald, Vlore, Albania, Zenelaj Engjellushe , HAWA Suada ,   Ministry of Education and Sports, Albania, DURMISHI Ermelinda ,   Ministry of Education and Sports, Albania, Beqiri Kevin ,   University College Reald, Vlore, Albania
Published: February 2024

Cross-Ref është një platformë e njohur ndërkombëtare për indeksimin e botimeve shkencore. Ky artikull analizon rolin dhe rëndësinë e indeksimit në Cross-Ref për revistat shkencore dhe si ky proces ndikon në integritetin e kërkimeve shkencore, zhvillimin institucional dhe individual. Në këtë artikull, është bërë një analizë e thellë e efekteve të indeksimit në Cross-Ref në revistat shkencore, duke përfshirë rritjen e vizibilitetit të tyre, si dhe ndikimin në kualitetin e kërkimeve dhe citimet e autorëve. Po ashtu, është shqyrtuar se si indeksimi në Cross-Ref mund të ndikojë në financimin dhe zhvillimin institucional të institucioneve akademike dhe hulumtuese, duke rritur reputacionin e tyre dhe arritjet shkencore. Përmes një analize empirike të procesit të indeksimit të revistës shkencore Buletini Shkencor Reald, e cila është botim i Kolegjit Universitar Reald janë identifikuar avantazhet dhe sfidat e indeksimit në Cross-Ref për autorët e individëve, institucionet e tyre dhe revistat shkencore. Në fund të artikullit, paraqiten përfunime dhe rekomandime për autorët, redaktorët e revistave dhe institucionet për të përfituar maksimalisht nga ky proces dhe për të ruajtur integritetin e kërkimit shkencor në një mjedis të ndryshëm shkencor. Ky artikull ofron një perspektivë të thellë dhe reale mbi rolin e indeksimit në Cross-Ref dhe efektet e tij në botën e kërkimit shkencor dhe institucioneve akademike, duke nxitur një diskutim më të gjerë për temën në fushën e studimeve shkencore.
SFIDAT E UNIVERSITETEVE PËR KËRKIMIN SHKENCOR NË BALLKANIN PERËNDIMOR
Authors:   University College Reald, Vlore, Albania, Zenelaj Engjellushe , HAWA Suada ,   Ministry of Education and Sports, Albania, DURMISHI Ermelinda ,   Ministry of Education and Sports, Albania
Published: February 2024

Ky artikull ka për qëllim të shqyrtojë dhe të analizojë sfidat në kërkimin shkencor në universitetet e Ballkanit Perëndimor. Analiza përqendrohet në identifikimin e problematikave kryesore që ndikojnë në nivelin e kualitetit të kërkimit shkencor në këto universitete duke sjellë në fokus vështirësitë financiare, standardet e ulëta të prosecit mësimor, dhe mungesën e bashkëpunimit ndërmjet institucioneve,. Nëpërmjet një analize të përditësuar, identifikohen faktorët kryesorë që kontribuojnë në këto sfida. Një vëmendje e posaçme i kushtohet ndikimit të kushteve financiare në zhvillimin e kërkimit shkencor, si dhe mungesës së standardeve të larta akademike. Ky artikull gjatë trajtimit të kësaj teme përfshin edhe sugjerime konkrete për të përmirësuar situatën, duke përfshirë hapa të mundshëm për të rritur bashkëpunimin ndërmjet universiteteve dhe për të avancuar standardet e kërkimit shkencor në rajon. Kjo analizë synon të jetë një kontribut për të adresuar sfidat që ballafaqohen universitetet e Ballkanit Perëndimor në fushën e kërkimit shkencor dhe të ofrojë rekomandime konkrete për përmirësimin e situatës aktuale.
Pengaruh Potongan Harga Dan Layout Terhadap Kunjungan pelanggan Pada Sinar Jaya Swalayan Toboh Pariaman
Authors: Safardi Safardi , Rahayu Sari
Published: February 2024

Banyaknya supermarket yang bermunculan di Pariaman menimbulkan persaingan harga yang berdampak pada kunjungan ke supermarket tersebut. Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis pengaruh potongan harga dan layout terhadap kunjungan pelanggan di Sinar Jaya Swalayan Toboh Pariaman. Penelitian ini menggunakan model analisis deskriptif dan kuantitatif dengan metode analisis regresi berganda. Teknik yang digunakan untuk menentukan sampel dalam penelitian ini adalah teknik simple random sampling sehingga diperoleh total 33 sampel pelanggan Sinar Jaya Swalayan Toboh Pariaman. Hasil penelitian menunjukkan bahwa nilai signifikansi variabel potongan harga sebesar 0,000 < 0,05. Diskon (X1) berpengaruh signifikan terhadap kunjungan pelanggan di Sinar Jaya Swalayan Toboh Pariaman. Nilai signifikansi variabel tata letak (X2) adalah 0,000 < 0,05. layout berpengaruh signifikan terhadap kunjungan pelanggan di Sinar Jaya Swalayan Toboh Pariaman. Uji F diperoleh nilai F hitung = 167,630 dengan sig = 0,000 < 0,05.
PENGARUH MOTIVASI DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN PT. RAHMAN JAYA MAKMUR DI SAMARINDA
Authors: Sattar Sattar , Saiful Saiful , Romadloni Moh. , Aisyah Siti Nur
Published: February 2024

This study aims to determine: (1) the effect of motivation on employee performance; (2) the effect of work discipline on employee performance; (3) the influence of motivation and work discipline together on the performance of employees at PT. Rahman Jaya Makmur in Samarinda. This is a research with a quantitative approach. A sample of 20 employees was determined by saturation or census sampling. Data collection techniques using a questionnaire. Test the validity of the instrument items using the Product Moment correlation technique and test the reliability using Cronbach Alpha. Analysis prerequisite test consists of normality test, multicollinearity test, autocorrelation test. Data analysis in order to answer research questions with multiple regression analysis. The results showed that the variables of motivation and work discipline simultaneously had a significant effect on employee performance (0.009 0.05). Meanwhile, the work discipline variable partially has a significant effect on employee performance, this is indicated by a significant value of 0.006 (0.006
EVALUASI KERASIONALAN PENGGUNAAN OBAT ARV (ANTI RETROVIRAL) PADA PASIEN ODHA (ORANG DENGAN HIV AIDS) DI RUMAH SAKIT UMUM DAERAH KOTA TANGERANG PERIODE OKTOBER – DESEMBER 2022
Authors: Astuti Tri , Panduwiguna Ivans , Nugrahini Lestari
Published: February 2024

Abstrak

 Antiretroviral (ARV) merupakan obat yang digunakan pasien HIV/AIDS untuk mengurangi resiko penularan HIV, menghambat perburukan infeksi oportunistik, menurunkan jumlah virus dalam darah sampai tidak terdeteksi dan meningkatkan kualitas hidup pasien HIV/AIDS. Penelitian ini dilakukan dengan metode deskriptif dengan pengambilan data secara retrospektif dari catatan rekam medis pada bulan Oktober - Desember 2022 di RSUD Kota Tangerang. Obat ARV yang paling banyak digunakan yaitu Triple FDC sebanyak 61 % dimana usia pasien yang paling banyak terkena HIV/AIDS yaitu pasien dengan usia produktif yaitu umur 26 – 45 tahun sebesar 63% dan paling banyak pasien laki-laki dengan jumlah 81%

 

Kata Kunci :Anti Retroviral, Evaluasi Penggunaan Obat, HIV/AIDS
ANALISIS TEPAT OBAT DAN TEPAT DOSIS PENGGUNAAN OBAT ANTIINFLAMASI NON STEROID (AINS) DI APOTEK INA FARMA PERIODE 2022/2023
Authors: Wika I Gede Wika Gita Septiadi , Nugrahini Lestari , Puspaningrat Luh Putu Desy
Published: February 2024

Septiadi, Gita, Wika, Gede, I. 2023. Analisis Tepat Obat Dan Tepat Dosis Penggunaan Obat Antiinflamasi Non Steroid (AINS) Di Apotek Ina Farma Periode 2022/2023 . Skripsi Penelitian, Program Studi  Ilmu Farmasi, Sekolah Tinggi Ilmu Kesehatan Buleleng. Pembimbing (1) apt. Lestari Nugrahini, S.Farm., M.Farm. Pembimbing (2) Luh Desi Puspaningrat, S.Km.,M,Si

 

Nyeri merupakan sebuah gangguan kesehatan yang sering dialami oleh masyarakat. Nyeri pada setiap orang berbeda dalam hal skala maupun tingkatannya dan hanya orang itulah yang dapat menjelaskan atau mengevaluasi rasa nyeri yang dialaminya dan penggunaan obat Antiinflamasi Non  Steroid (AINS) masih menjadi pilihan utama sebagai terapi farmakologi Adanya efek samping yang bisa terjadi maka perlu ditunjang dengan penggunaan yang rasional khususnya pada fasilitas kesehatan penelitian ini bertujuan untuk menganalisis penggunaan obat antiinflamasi non steroid (AINS). Jenis penelitian ini merupakan penelitian non eksperimental dengan desain deskriptif kuantitatif.  Sampel diambil dengan cara total sampling dari populasi yang memenuhi kriteria, inklusi resep periode Januari sampai dengan  Maret 2023 dan memiliki data resep insscriptio, invovatio,signatura, subscriptio,  pro. Jumlah sampel yang diperoleh yaitu sebesar 44.

 

Kata kunci : Tepat Dosis dan Tepat Obat, Instalasi Farmasi Apotek
Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data
Authors:   Bioinformatics Program, University of Arkansas for Medical Sciences and University of Arkansas at Little Rock, Little Rock, AR, 72205, USA, Mainali Nirjal
Published: February 2024

Many age-progressive diseases are accompanied by (and likely caused by) the presence of protein aggregation in affected tissues. Protein aggregates are conjoined by complex protein-protein interactions, which remain poorly understood. Knowledge of the proteins that comprise aggregates, and their adherent interfaces, can be useful to identify therapeutic targets to treat or prevent pathology, and to discover small molecules for disease interventions. We present web-based software to evaluate and rank influential proteins and protein-protein interactions based on graph modelling of the cross linked aggregate interactome. We have used two network-graph-based techniques: Leave-One-Vertex-Out (LOVO) and Leave-One-Edge-Out (LOEO), each followed by dimension reduction and calculation of influential vertices and edges using Principal Components Analysis (PCA) implemented as an R program. This method enables researchers to quickly and accurately determine influential proteins and protein-protein interactions present in their aggregate interactome data.
Serum sclerostin levels as a diagnostic marker for osteoporosis
Authors:   Department of Biochemistry, Dhanalakshmi Srinivasan Medical College and Hospital, Affiliated to The Tamilnadu Dr MGR Medical University, Perambalur 621 113, Tamil Nadu, India, Paranthaman Modagan
Published: February 2024

Osteoporosis is asymptomatic, in which low bone-mass and micro-architectural deterioration of bone tissue leads to increasing bone fragility and fracture. Vertebral and hip fractures lead to increased mortality, resulting in enormous health care costs. BMD testing by DEXA is used in diagnosis of osteoporosis. However, low-and middle-income populations are unable to conduct periodic examinations of bone mineral status. Thus, current study is mainly aimed at finding a cost-effective diagnostic-marker for osteoporosis. 170 participants, of whom 51 had osteoporosis, 62 had osteopenia and 57 had normal bone-mass. Selection of individuals was based on DEXA scan BMD. Sclerostin was determined by ELISA. The variables were compared using ANOVA test and ROC analysis was performed. Sclerostin levels were significantly decreased in osteoporosis (4.62 ą 1.6 ng/mL) and osteopenia (4.92 ą 1.4 ng/mL) compared with controls (5.74 ą 1.3 ng/mL), (p < 0.0001). Sclerostin level 5.6 ng/mL is the cut-off value for diagnostic purpose, according to good sensitivity and specificity. In patients with osteopenia and osteoporosis, decreased sclerostin levels were associated with an increased disease risk. These relationships were independent of BMD and bone turnover, suggesting that Sclerostin levels may reflect disease-severity in osteoporosis. Sclerostin measurements could become a useful clinical index for diagnosis of osteoporosis.
Terapia cognitivo-comportamental no tratamento da depressão: relato de experiência
Authors: Souza Mascarenhas Vitor
Published: February 2024

A depressão é um dos transtornos psiquiátricos mais prevalentes no mundo. No Brasil, segundo a Organização Mundial da Saúde (OMS) a sua prevalência é de 13 a 16% da população, sendo umas causas mais incapacitantes para as pessoas. O objetivo deste estudo foi demonstrar a eficácia da terapia cognitivo-comportamental no tratamento do transtorno depressivo na prática clínica. Foram utilizados os instrumentos: inventários de sintomas de ansiedade de Beck (BAI); inventário de sintomas de depressão de Beck (BDI-II) e escala de desesperança de Beck (BHS). Foram realizados quinze atendimentos, com melhoras significativas dos sintomas relatados pelo cliente. O desenvolvimento dos atendimentos de forma criteriosa nesta abordagem se mostrou eficiente, comprovando os vários estudos e literatura sobre o tema.
Distribution of Hornbills and Important Hornbill Landscapes - Setting Site Conservation Priorities for Peninsular Malaysia
Authors:   Malaysian Nature Society, Perumal Balu , Chin Aik Yeap ,   Malaysian Nature Society,   Universiti Putra Malaysia
Published: February 2024

Malaysia is an important hornbill range country in Asia supporting a total of 10 hornbill species. Malaysia ranks second (collectively with Myanmar and the Philippines) after Thailand and Indonesia (both 13 species respectively) in terms of hornbill diversity per country. Within Malaysia, all 10 species has been recorded in Peninsular Malaysia whereas Sabah and Sarawak have 8 species each. The Great Hornbill Buceros bicornis and Plain-pouched Hornbill Rhyticeros subruficollis do not occur in Borneo. Despite being iconic tropical forest birds, our understanding of its local distribution status, ecology and biology remains limited. In this paper, we conducted a broad examination of the hornbills’ distribution in Peninsular Malaysia based on more recent information gleaned mostly from grey literature e.g. birding trip reports, scientific expedition reports, department annual reports, selected Facebook birding group postings, proceedings, bird databases (MNS Bird-I-Witness) etc. Information from primary literature e.g. local/regional journals were also taken into account where available. The purpose of this exercise is two-fold, (1) to update our knowledge post-Wells (1999) about hornbill distributions in Peninsular Malaysia in light of continuing deforestation and habitat degradation and (2) identify Important Hornbill Landscapes (IHL) in need of protection and conservation to preserve viable hornbill populations.
Wreathed Hornbill (Rhyticeros undulatus) in Mount Ungaran Central Java: Status and Factors that Threaten Its Existence
Authors:   Universitas Negeri Semarang, Rahayuningsih Margareta , Edi Nugroho , Utami Nur Rahayu , D. Jamaludin , Ahmad Tsabit Azinar
Published: February 2024

Mount Ungaran in Central Java is one of the Important Birds Areas (IBA) in Indonesia where one of the Hornbill species, Wreathed Hornbill (Rhyticeros undulatus) is found. Based on the IUCN 2016, Wreathed Hornbill has been listed as Least Concern (LC) and listed in Appendix II of the CITES. In order to conduct preservation and in-situ conservation planning of Wreathed Hornbill scientific data on ecology is needed. Therefore, the research on the Wreathed Hornbill in Mount Ungaran has been planned since 2010‒2016. The results include species identification, early population and distribution, daily behaviour, habitat profile, nest-site characteristics, feeding behaviour, food consumed, habitat suitability and threats. While study on the dynamics of the home range of Wreathed Hornbill in Mount Ungaran is still ongoing. The implementation of this research is jointly pursued with the Forest Department, Natural Resources Conservation Center (BKSDA), Perhutani Central Java, Indonesia Hornbill, and LIPI (Indonesian Institute of Sciences), and IBBS (Indonesian Bird Banding Scheme).
Sumatran Hornbills in Fragmented Forest Areas in Oil Pam Plantation in South Solok, West Sumatra
Authors:   Andalas University, Padang, Dharma Fernando , Novarino Wilson ,   Andalas University, Padang, Nurdin Jabang ,   Andalas University, Padang
Published: February 2024

A study on hornbill populations in fragmented forest areas within oil palm plantations in Tidar Kerinci Agung (TKA) Company, West Sumatra was carried out from July to August 2015 in 60 Hectare fragmented forest areas. The objective of this study was to document hornbill species richness using the transect method on three main lines along two km and using call recognition for population census of hornbill. During the study, we recorded 82 individuals of eight species after 60 km walk. We encountered using two methods (Sighting and Calls Methods); Anorrhinus galeritus twenty-one encounters, Berenicornis comatus single encounter, Rhabdotorrhinus corrugatus two encounters, Rhyticeros undulatus two encounters, Anthracoceros malayanus sixteen encounters, Anthracoceros albirostris seven encounters, Buceros rhinoceros thirty-one encounters and two encounters of Rhinoplax vigil.
Habitat and Conservation Status of Rufous-necked Hornbill in Jigme Singye Wangchuck National Park, Bhutan
Authors:   Department of Forest and Park Services, Dorji Sonam
Published: February 2024

The Rufous-necked Hornbill habitat characteristics and conservation was studied in Jigme Singye Wangchuck National Park (JSWNP). The focal-bird approaches was used to determine the habitat components such as, the structure on vegetation, species composition; food-trees and nesting were assessed in the hornbill habitat. A total of 78 respondents were interviewed from five villages using semi-structured questionnaires. Vegetation assessment showed that the evergreen broad-leaved tree has the highest percentage share of 62.5%. A total of 42 tree species and 9 food-tree species, dominated by Lauraceae family in Tingtibi, and 35 tree species and 8 food-tree species, dominated by Hemamelidaceae in Nabji were recorded. Diameter at breast height size of tree species ranges from 14 cm to 250 cm. Nests were found in the cavities of living tree trunks of different tree species having large girth and tall trees. Rural timber extraction, land use changes, cattle grazing, and the roads and utility corridors contribute significant threats to the hornbill habitat. About 93.6% of the respondents had strong liking towards hornbill. Using hornbill as flagship or umbrella species would contribute to long-term conservation of hornbill.