bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: FeCl3‐Promoted [3 + 3] Cycloaddition: Efficient Preparation of 1,2‐Dihydro‐2‐oxo‐3‐pyridinecarboxylate and 1,2‐Dihydro‐2‐oxo‐3‐pyridinecarboxamide Derivatives.
Authors: Li Shuheng , Wang Shaozhong
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fast and Convenient Base‐Mediated Synthesis of 3‐Substituted Quinolines.
Authors: Vander Mierde Hans , Van Der Voort Pascal , Verpoort Francis
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 5‐Hydroxymethyl‐8‐methyl‐3‐(3‐aryl‐[1,2,4]oxadiazol‐5‐yl)‐2H‐pyrano [2,3‐c]pyridin‐2‐ones and Their Esters.
Authors: Zhuravel Irina O. , Kovalenko Sergiy M. , Zaremba Oleg V. , Detistov Oleksandr S. , Kovalenko Svitlana S. , Chernykh Valentin P.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New Fused Isoquinolines via Reissert Compounds.
Authors: Fuchs Christian , Bender Christoph , Ziemer Burkhard , Liebscher Juergen
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2,4‐Disubstituted 6‐Phenyl‐7H‐pyrrolo[3,2‐d]pyrimidin‐7‐one 5‐Oxides.
Authors: Cikotiene Inga , Pudziuvelyte Erika , Brukstus Algirdas
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of Quinoxaline Derivatives Mediated by Stannous Chloride.
Authors: Shi Da‐Qing , Dou Guo‐Lan , Ni Sai‐Nan , Shi Jing‐Wen , Li Xiao‐Yue
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Cyclization‐[3 + 3] Cycloaddition Reactions of 2‐Alkynylbenzaldoxime: Synthesis of Fused 1,2‐Dihydroisoquinolines.
Authors: Ding Qiuping , Wang Zhiyong , Wu Jie
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Synthesis of New Regioisomeric 6,7‐Dihydroindeno[1,2‐e]pyrimido[4,5‐b][1,4]diazepin‐5(5aH)‐ones.
Authors: Insuasty Braulio , Orozco Fabian , Garcia Angelica , Quiroga Jairo , Abonia Rodrigo , Nogueras M. , Cobo Justo
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Application of the Acetate of Baylis—Hillman Adducts of Salicylaldehydes in the Synthesis of Methyl 2‐Oxo‐2,3‐dihydrobenzo[b]oxepine‐4‐carboxylates.
Authors: Ahn Sang‐Hyun , Lim Hee Nam , Lee Kee‐Jung
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Wittig Olefination and Thiol Mediated 7‐endo‐Trig Radical Cyclization: Novel Synthesis of Oxepin Derivatives.
Authors: Majumdar K. C. , Taher Abu
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Cyclization of N‐{2‐[(2‐Carboxyethyl)sulfanylphenyl]}‐β‐alanines.
Authors: Rutkauskas K. , Kantminiene K. , Beresnevicius Z. J.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of P,N‐Heterocycles from ω‐Amino‐H‐phosphinates: Conformationally Restricted α‐Amino Acid Analogues.
Authors: Queffelec Clemence , Ribiere Patrice , Montchamp Jean‐Luc
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 4‐, 5‐, 6‐, and 7‐Azidotryptamines.
Authors: Friedrich Anne , Braese Stefan , O'Connor Sarah E.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 7‐Epineoptilocaulin (Ia), Mirabilin B (IIa), and Isoptilocaulin (III). A Unified Biosynthetic Proposal for the Ptilocaulin and Batzelladine Alkaloids. Synthesis and Structure Revision of Netamines E and G.
Authors: Yu Min , Pochapsky Susan S. , Snider Barry B.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two New Ceramides from the Radix of Angelica sinensis.
Authors: Lue Jie‐Li , Duan Jin‐Ao , Tang Yu‐Ping , Ge Yue‐Lan
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Antitumoral and Antileishmanial Dioncoquinones and Ancistroquinones from Cell Cultures of Triphyophyllum peltatum (Dioncophyllaceae) and Ancistrocladus abbreviatus (Ancistrocladaceae).
Authors: Bringmann Gerhard , Ruedenauer Stefan , Irmer Andreas , Bruhn Torsten , Brun Reto , Heimberger Tanja , Stuehmer Thorsten , Bargou Ralf , Chatterjee Manik
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereoselective Synthesis of α‐Tocopherol: A New Concept for the Formation of Chromanols.
Authors: Chapelat Julien , Buss Axel , Chougnet Antoinette , Woggon Wolf‐D.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Acremoxanthones A and B, Novel Antibiotic Polyketides from the Fungus Acremonium sp. BCC 31806.
Authors: Isaka Masahiko , Palasarn Somporn , Auncharoen Patchanee , Komwijit Somjit , Jones E. B. Gareth
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (+)‐Superstolide A.
Authors: Tortosa Mariola , Yakelis Neal A. , Roush William R.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Citrafungin A.
Authors: Calo Frederick , Richardson Jeffery , Barrett Anthony G. M.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Toward an Improved Clustering of Large Data Sets Using Maximum Common Substructures and Tolological Fingerprints.
Authors: Boecker Alexander
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: FieldScreen: Virtual Screening Using Molecular Fields. Application to the DUD Data Set.
Authors: Cheeseright Timothy J. , Mackey Mark D. , Melville James L. , Vinter Jeremy G.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Markup, XML and the World‐Wide Web. Part 8. Polymer Markup Language.
Authors: Adams Nico , Winter Jerry , Murray‐Rust Peter , Rzepa Henry S.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Identification and Selection of “Privileged Fragments” Suitable for Primary Screening.
Authors: Gianti Eleonora , Sartori Luca
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Protein—Ligand Docking Against Non‐Native Protein Conformers.
Authors: Verdonk Marcel L. , Mortenson Paul N. , Hall Richard J. , Hartshorn Michael J. , Murray Christopher W.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: In silico Mutagenesis and Docking Studies of Pseudomonas aeruginosa PA‐IIL Lectin — Predicting Binding Modes and Energies.
Authors: Adam Jan , Kriz Zdenek , Prokop Martin , Wimmerova Michaela , Koca Jaroslav
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Reacting Transport Phenomena and Multiscale Models for SOFCs
Authors: Andersson M. , Yuan J. , Sunden B.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Neutron Studies of Stretched Dihydrogen Complexes: A Model for a “Reaction Pathway” of Oxidative Addition of a Metal Atom to an H—H Bond
Authors: Aznavour Kristen , Bau Robert
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydroxyalkylammonium Salts of Organylsulfanyl(sulfonyl)acetic Acids — New Stimulators of Biological Processes
Authors: Mirskova A. N. , Levkovskaya G. G. , Mirskov R. G. , Voronkov M. G.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Enantioselective Synthesis of Linear β‐Amino Alcohols
Authors: Metro Thomas‐Xavier , Gomez‐Pardo Domingo , Cossy Janine
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Mitsunobu Reaction in the Chemistry of Nitrogen‐Containing Heterocyclic Compounds. The Formation of Heterocyclic Systems
Authors: Golantsov N. E. , Karchava A. V. , Yurovskaya M. A.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Louis Fieser: An Organic Chemist in Peace and War
Authors: Lenoir Dieter , Tidwell Thomas T.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Glycosyl Oxygen Compounds (Except Di‐ and Oligosaccharides)
Authors: Kryczka B. , Lewkowski J. , Zawisza A.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Sesquiterpenes via Silicon‐Guided Rearrangement of Epoxydecalins
Authors: Blay Gonzalo , Collado Ana M. , Garcia Begona , Pedro Jose R.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Radical Addition of Dialkyl Phosphites: Application in Organic Synthesis
Authors: Rakhimov A. I.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Dioxanes, 1,3‐Dioxepanes, and Larger‐Ring O/O Acetals
Authors: Kouklovsky C.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Dioxetanes and 1,3‐Dioxolanes
Authors: Cordier C. , Leach S. , Nelson A.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Functionalization of Indole and Pyrrole Cores via Michael‐Type Additions
Authors: Saracoglu Nurullah
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxo and Imido Complexes of Rhenium and Molybdenum in Catalytic Reductions
Authors: Du Guodong , Abu‐Omar Mahdi M.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Development on Catalytic Reductive Amination and Applications
Authors: Tripathi Rama P. , Verma Shyam S. , Pandey Jyoti , Tiwari Vinod K.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Self‐Assembled Organic Microtubes from Amphiphilic Molecules
Authors: Lee Ho Yong , Nam Seong Ryong , Hong Jong‐In
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Do We Understand the Recyclability of Ionic Liquids?
Authors: Wu Bo , Liu WeiWei , Zhang YuMei , Wang HuaPing
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Clinical and pathologic prognostic features in acinic cell carcinoma of the parotid gland
Authors: Gomez Daniel R. , Katabi Nora , Zhung Joanne , Wolden Suzanne L. , Zelefsky Michael J. , Kraus Dennis H. , Shah Jatin P. , Wong Richard J. , Ghossein Ronald A. , Lee Nancy Y.
Published: March 2009

BACKGROUND:

To the authors' knowledge, the indications for adjuvant treatment in acinic cell carcinoma (AciCC) of the parotid gland have not been elucidated to date. The aim of the current study was to determine patterns of failure and adverse prognostic features.

METHODS:

Between March of 1989 and August of 2006, 35 patients underwent surgery at Memorial Sloan‐Kettering Cancer Center for AciCC of the parotid gland and had their clinical and pathologic features retrospectively analyzed at the primary site. All cases were reviewed by 2 head and neck pathologists. Five‐year estimates of survival outcomes were performed, followed by univariate analysis of potential prognostic features.

RESULTS:

The T classifications were as follows: T1 in 46% of patients, T2 in 23% of patients, T3 in 18% of patients, and T4 in 9% of patients. Three patients had cervical lymph node involvement. All patients underwent surgery as their primary treatment. Approximately 63% of patients (n = 22) received radiation treatment. The median follow‐up time for surviving patients was 59.9 months. Five‐year estimates of disease‐free survival (DFS), overall survival (OS), and local control were 85%, 90%, and 90%, respectively. Of the clinical variables tested, clinical extracapsular extension (ECE), facial nerve sacrifice, and lymph node involvement were found to be significantly associated with a detriment in DFS and OS (P < .05). Positive surgical margins, histologic ECE, >2 mitoses per 10 high‐power fields (HPF), atypical mitosis, vascular invasion, perineural invasion, pleomorphism, and necrosis were associated with adverse DFS (P < .05). All of these variables except for vascular invasion (P = .377) and perineural invasion (P = .07) were associated with OS. If high‐grade tumors were defined on the basis of high mitotic activity (>2 mitoses/10 HPF) and/or tumor necrosis, high‐grade carcinomas had a significantly lower DFS and OS (P = .001).

CONCLUSIONS:

AciCC had a low treatment failure rate, and a large number of patients could be considered candidates for surgery only. A histologic grading system was devised to help stratify patients for adjuvant treatment. Cancer 2009. © 2009 American Cancer Society.
Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer
Authors: Iwakiri Shotaro , Mino Nobuya , Takahashi Tsuyoshi , Sonobe Makoto , Nagai Shinjiro , Okubo Kenichi , Wada Hiromi , Date Hiroshi , Miyahara Ryo
Published: March 2009

BACKGROUND:

The authors elucidated particular chemokine receptors that are expressed on lung cancer cells, as well as the clinical significance of the expression of these chemokine receptors in completely resected nonsmall cell lung cancer (NSCLC).

METHODS:

The authors examined gene expression of chemokine receptors (CCR1‐11, CXCR1‐7, XCR1, and CX3CR1) in 11 cell lines of lung cancer, and gene expression of CXCR3, CXCR4, and CXCR7 (CXCR3/4/7) in surgical specimens of 127 patients who underwent complete resection for their NSCLC between May 2001 and December 2002, using quantitative real‐time reverse transcriptase–polymerase chain reaction (PCR). Mutation detection analysis of the EGFR genes using the PCR single‐strand conformational polymorphism method was evaluated in patients with pathological (p‐) stage I adenocarcinoma.

RESULTS:

Substantial expression of CXCR3/4/7 mRNA was observed in all NSCLC cell lines examined. In p‐stage I NSCLC, CXCR4 and CXCR7 expression values in patients with postoperative metastatic recurrence (Rec‐Distant) were significantly higher than in those without recurrences (P = .003 and P = .007, respectively). In addition, the 5‐year disease‐free survival (DFS) rate of high CXCR7‐expressing patients (63.2%) was significantly lower than that of low CXCR7‐expressing patients (84.8%) (P = .033). The EGFR mutation was significantly more frequent in patients with higher CXCR7 expression (14 of 21 patients) than in those with lower CXCR7 expression (12 of 32 patients) (P = .038). A multivariate analysis confirmed that high CXCR7 expression was an independent and significant factor predicting a poor DFS in p‐stage I NSCLC patients (P = .041).

CONCLUSIONS:

Higher expression of CXCR7 is associated with Rec‐Distant and poor DFS in patients with p‐stage I NSCLC. Cancer 2009. © 2009 American Cancer Society.
The effect of modafinil on cognitive function in breast cancer survivors
Authors: Kohli Sadhna , Fisher Susan G. , Tra Yolande , Adams M. Jacob , Mapstone Mark E. , Wesnes Keith A. , Roscoe Joseph A. , Morrow Gary R.
Published: March 2009

BACKGROUND:

The authors conducted a randomized clinical trial examining the effects of modafinil in reducing persistent fatigue in patients after treatment for cancer and performed secondary analyses to assess the effect of modafinil on cognitive function.

METHODS:

Breast cancer patients who reported a score of ≥2 on the Brief Fatigue Inventory were enrolled in the study. In phase 1 (P1), patients received 200 mg modafinil open‐label once daily for 4 weeks. In phase 2 (P2), patients with a positive response after P1 were randomized either to an additional 4 weeks of modafinil or to placebo. Tests of memory and attention selected from the Cognitive Drug Research (CDR) computerized cognitive assessment were performed at baseline (before modafinil) and after completing phases 1 and 2. The paired differences for each test score were subjected to a Wilcoxon signed rank test.

RESULTS:

Of the 82 women who were enrolled, 76 completed P1, and 68 completed all assessments in the study. Modafinil had a significant effect on the Speed of Memory (P = .0073) and Quality of Episodic Memory (P < .0001) during P1 of the study. After randomization at Week 8, those patients who continued modafinil demonstrated significantly greater improvement in Speed of Memory (P = .029), Quality of Episodic Memory (P = .0151), and mean Continuity of Attention (P = .0101) relative to the group that was switched to placebo.

CONCLUSIONS:

The authors found that modafinil improved cognitive performance in breast cancer survivors by enhancing some memory and attention skills. Although confirmation is needed, these findings suggest that modafinil may enhance quality of life in this patient population. Cancer 2009. © 2009 American Cancer Society.
Selective Enhancement of Carbon Nanotube Photoluminescence by Resonant Energy Transfer
Authors: Ahmad Ashraf , Kern Klaus , Balasubramanian Kannan
Published: March 2009

Highly selective: Enhancement of the photoluminescence (PL) emission efficiency of selected chiral forms of semiconducting single‐walled carbon nanotubes (SWCNTs) is presented (see figure). Excitation of Nile blue A in the presence of SWCNTs results in the quenching of its fluorescence. The energy is resonantly transferred to the (7,5) SWCNT whereas the (8,7) tube is not in resonance; hence, its PL remains unaffected.

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We report on a simple method for enhancing the efficiency of photoluminescence (PL) emission from selected chiral forms of semiconducting single‐wall carbon nanotubes (SWCNTs). The method is based on the use of a fluorescent dye (Nile blue A) that shows the capability of resonant energy transfer on to nanotubes. The excitation of Nile blue A in the presence of SWCNTs results in the quenching of its fluorescence and the energy is resonantly transferred to certain chiral forms. The PL emission from these chiral forms shows a marked increase in efficiency signifying the occurrence of Förster type resonant energy transfer (FRET). Due to its simplicity, this procedure has widespread implications for the detection of carbon nanotubes as well as for their use as fluorophores in FRET‐based in vivo and in vitro biological applications.
Localized Electrografting of Vinylic Monomers on a Conducting Substrate by Means of an Integrated Electrochemical AFM Probe
Authors: Ghorbal Achraf , Grisotto Federico , Charlier Julienne , Palacin Serge , Goyer Cédric , Demaille Christophe
Published: March 2009

An electrochemical lithographic toolfor locally electrografting a non‐conducting organic coating on a conducting substrate with a submicrometer resolution is provided by atomic force scanning electrochemical microscopy (AFM‐SECM). The picture shows the topographic AFM image of the line pattern drawn with an AFM‐SECM tip on a gold surface by direct reduction of an aryl diazonium salt/acrylic acid electrolyte solution.

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Combinations of scanning electrochemical microscopy (SECM) with other scanning probe microscopy techniques, such as atomic force microscopy (AFM), show great promise for directing localized modification, which is of great interest for chemical, biochemical and technical applications. Herein, an atomic force scanning electrochemical microscope is used as a new electrochemical lithographic tool (L‐AFM‐SECM) to locally electrograft, with submicrometer resolution, a non‐conducting organic coating on a conducting substrate.
Role of Excited States in Low‐Energy Electron (LEE) Induced Strand Breaks in DNA Model Systems: Influence of Aqueous Environment
Authors: Kumar Anil , Sevilla Michael D.
Published: March 2009

Low‐energy electrons (LEEs) interact with a DNA model system to create a variety of excited states. In the gas phase, dissociative (σ*) states are accessible by LEEs with energy <4 eV (see picture) and cause facile strand breaks through a dissociative electron attachment mechanism. However, under solvation these dissociative (σ*) states are blue‐shifted and are less accessible to LEEs.

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In Situ Plasmon‐Heating‐Induced Generation of Au/TiO2 “Hot Spots” on Colloidal Crystals
Authors: Alessandri Ivano , Ferroni Matteo , Depero Laura E.
Published: March 2009

SERS you right: The plasmon heating of gold nanoshells is exploited to yield the local conversion of amorphous TiO2 into anatase on the surface of polymeric colloidal crystals (see scheme). The resulting Au/TiO2 spots are active substrates for surface‐enhanced Raman spectroscopy and allow surface reactions and processes to be followed directly on‐site.

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Influence of Sodium Cations of N3 Dye on the Photovoltaic Performance and Stability of Dye‐Sensitized Solar Cells
Authors: Andrade Luísa , Zakeeruddin Shaik M. , Nazeeruddin Mohammad K. , Aguilar Ribeiro Helena , Mendes Adélio , Grätzel Michael
Published: March 2009

Little things count: The number of protons and the nature of cations of the dye influence the open‐circuit potential and the short circuit current of dye‐sensitized solar cells (DSCs, see picture). Thus, the effect of substituting the two tetrabutylammonium counter ions in the standard N719 dye by sodium ions allows the improvement on the performance and stability of DSCs.

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We report on the effect of substituting the two tetrabutyl ammonium counter ions of the standard N719 dye by sodium ions on the performance and stability of dye‐sensitized solar cells (DSCs). The disodium analogue of N719 in conjunction with a non‐volatile electrolyte gives a conversion efficiency of 7.6 % under standard global AM 1.5 sunlight. Devices maintain 99 % of their initial performance after 1000 h under full sunlight aging at 50 °C. Electrochemical impedance spectroscopy and photovoltage transient decay studies reveal the evolution of the solar cell parameters during aging. Remarkably, upon aging a decrease in the rate of electron back reaction with the triiodide ions across the TiO2/electrolyte interface appears as well as enhanced electronic conduction in the TiO2 film.
A Ru‐Hbpp‐Based Water‐Oxidation Catalyst Anchored on Rutile TiO2
Authors: Francàs Laia , Sala Xavier , Benet‐Buchholz Jordi , Escriche Lluís , Llobet Antoni
Published: March 2009

In support of a split: A water oxidation catalyst based on ruthenium bis‐(2‐pyridyl)pyrazole anchored on rutile TiO2 was prepared. The performance of this new material with regard to its capacity to catalytically oxidize water to molecular oxygen in a heterogeneous phase was evaluated.

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Two organic ligands based on bis‐(2‐pyridyl)pyrazole (Hbpp) functionalized with a para‐methylenebenzoic acid (Hbpp‐Ra) or its ester derivative (Hbpp‐Re) were prepared and characterized. The ester‐functionalized ligand was then used to prepare a series of related dinuclear ruthenium complexes of general formula [RuII2(L‐L)(bpp‐Rn)(trpy)2]m+ (L‐L=μ‐Cl, μ‐acetato, or (H2O)2; n=e or a; trpy=2,2′:6′,2′′‐terpyridine; m=2 or 3). The complexes were characterized in solution by 1D and 2D NMR spectroscopy, UV/Vis spectroscopy, and electrochemical techniques. The [RuII2(μ‐Cl)(bpp‐Re)(trpy)2](PF6)2 complex was further characterized in the solid state by X‐ray diffraction. The complexes containing the free carboxylic acid ligand were anchored onto rutile TiO2 and treated with 0.1 M triflic acid solution to generate the homologous water‐oxidation catalysts TiO2‐[RuII2(H2O)2(bpp‐Ra)(trpy)2]2+. This new hybrid material catalytically oxidizes water to molecular oxygen in a heterogeneous manner using CeIV as chemical oxidant. The generation of molecular oxygen is accompanied by the formation of carbon dioxide as well as some leaching of the Ru catalyst.
Olfactory association learning and brain‐derived neurotrophic factor in an animal model of early deprivation
Authors: Zimmerberg Betty , Foote Hannah E. , Van Kempen Tracey A.
Published: March 2009

Animal models can serve to explore neural mechanisms underlying the effects of stressful early experiences on behaviors supporting attachment. Neonatal rats primarily use olfaction for attachment, and Brain‐Derived Neurotrophic Factor (BDNF) may be a key transcription target in olfactory association learning. In this experiment, neonatal male and female rats were isolated individually for 3 hr daily in the first week of life while their dams were left with partial litters (Early Deprivation, ED) or remained undisturbed (Control). At 1 week of age, subjects were tested using a 2‐day classical conditioning paradigm. The conditioned group (O/M) was exposed to a novel odor paired with a milk infusion. Three additional groups included an unpaired odor and milk exposure group (O/M unP), an odor exposure alone group (O/NM), and neither an odor nor a milk group (NO/NM). Learning the odor association, as revealed in a position preference for the novel odor, was accompanied by an increase in hippocampal BDNF in O/M subjects from undisturbed Control litters. BDNF levels were also positively related to degree of preference for the odor in the O/M Control group. ED subjects did not make the classically conditioned odor association and did not show an increase in hippocampal BDNF. ED increased BDNF levels in the olfactory bulb compared to Controls regardless of training group; individual levels were not correlated with performance because samples were pooled. These results suggest that changes in the transcription of BDNF may underlie some of the long‐term consequences of the early stress of maternal separation. © 2009 Wiley Periodicals, Inc. Dev Psychobiol 51: 333–344, 2009.
Interpersonal interactions on online forums addressing eating concerns
Authors: Ransom Danielle C. , La Guardia Jennifer G. , Woody Erik Z. , Boyd Jennifer L.
Published: March 2009

Objective:

Although some research suggests that online eating disorder forums promote “pro‐eating‐disorder” lifestyles and discourage recovery, other research suggests that such forums are an important source of interpersonal support. The current study extends this research by exploring the positive and negative behaviors encouraged on these forums and by comparing forum members' perceptions of support received from online and offline relationships to support received in relationships of age‐matched controls.

Method:

In a survey of 60 forum members, we assessed information exchanged and support provided on eating disorder forums. Further, we assessed perceptions of social support for general and specific life concerns in this group of forum members as well as 64 age‐matched university controls.

Results:

Results show that both adaptive and maladaptive behaviors are encouraged on the forums, and that this encouragement has some influence on forum members trying out these behaviors. Overall, forum members reported receiving less support for their eating concerns as compared to their general life stressors, and they perceived less support for both their general concerns and eating concerns in their offline relationships as compared to their online forum relationships. Moreover, forum members reported receiving less support from their offline relationships as compared to support received in relationships by age‐matched controls.

Discussion:

Forum members perceive less support in their important relationships than other peers do, and they seek out and participate in forums as a means of attaining greater social support. However, our research suggests that these forums also encourage dysregulated eating behaviors. Implications of online forum support and its impact on recovery are discussed further. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord, 2010
Adaptation and evaluation of the Clinical Impairment Assessment to assess disordered eating related distress in an adolescent female ethnic Fijian population
Authors: Becker Anne E. , Thomas Jennifer J. , Bainivualiku Asenaca , Richards Lauren , Navara Kesaia , Roberts Andrea L. , Gilman Stephen E. , Striegel‐Moore Ruth H.
Published: March 2009

Objective:

Measurement of disease‐related impairment and distress is central to diagnostic, therapeutic, and health policy considerations for eating disorders across diverse populations. This study evaluates psychometric properties of a translated and adapted version of the Clinical Impairment Assessment (CIA) in an ethnic Fijian population.

Method:

The adapted CIA was administered to ethnic Fijian adolescent schoolgirls (N = 215). We calculated Cronbach's α to assess the internal consistency, examined the association between indicators of eating disorder symptom severity and the CIA to assess construct and criterion validity, and compared the strength of relation between the CIA and measures of disordered eating versus with measures of generalized distress.

Results:

The Fijian version of the CIA is feasible to administer as an investigator‐based interview. It has excellent internal consistency (α = 0.93). Both construct and criterion validity were supported by the data, and regression models indicated that the CIA predicts eating disorder severity, even when controlling for generalized distress and psychopathology.

Discussion:

The adapted CIA has excellent psychometric properties in this Fijian study population. Findings suggest that the CIA can be successfully adapted for use in a non‐Western study population and that at least some associated distress and impairment transcends cultural differences. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord, 2010
Perfectionism across stages of recovery from eating disorders
Authors: Bardone‐Cone Anna M. , Sturm Katrina , Lawson Melissa A. , Robinson D. Paul , Smith Roma
Published: March 2009

Objective:

This study examined perfectionism in relation to recovery from eating disorders by comparing different conceptualizations of perfectionism across healthy controls and fully recovered, partially recovered, and active eating disorder cases, where full recovery was defined using physical, behavioral, and psychological indices.

Method:

Participants were primarily young adult females; 53 active eating disorder cases, 15 partially recovered cases, 20 fully recovered cases, and 67 healthy controls. Participants completed questionnaires assessing trait perfectionism, perfectionistic self‐presentation style, and frequency of perfectionism cognitions, as well as a diagnostic interview to determine lifetime and current eating disorder diagnoses.

Results:

A robust pattern emerged whereby the fully recovered individuals and healthy controls had similar levels of perfectionism that were significantly lower than the perfectionism levels of the partially recovered and active individuals with eating disorder, who were comparable to each other.

Discussion:

These findings have implications for more clearly defining eating disorder recovery and for the role perfectionism may play in achieving full recovery. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord, 2010
Course and outcome of eating disorders in a primary care‐based cohort
Authors: van Son Gabriëlle E. , van Hoeken Daphne , van Furth Eric F. , Donker Gé A. , Hoek Hans W.
Published: March 2009

Objective:

To study the course and outcome of patients with eating disorder detected in primary care.

Method:

General practitioners (GP's) provided information on the course and outcome of eating disorders in patients (n = 147) diagnosed with anorexia nervosa (AN) or bulimia nervosa (BN) identified during a Dutch nationwide primary care‐based incidence study. The research team determined the outcome based on the data provided by the GP's. The mean duration of the follow‐up was 4.8 years.

Results:

About 57% of the patients initially diagnosed with AN and 61% of those diagnosed with BN were fully recovered. AN binge/purge subtype (ANBP) demonstrated the most extended median survival time of all diagnostic subgroups (the point at which half of the group has reached full recovery). Diagnostic crossover was low. A younger age at detection predicted recovery at outcome for AN and BN. One patient (AN) died.

Discussion:

The results of this study on differences in outcome and low crossover support the diagnostic distinction between AN and BN in the DSM‐IV. Early detection is of major importance for a favorable outcome. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord, 2010
Robust estimation of driver posture in the presence of lighting changes
Authors: Takahashi Daisuke , Okamoto Noriyoshi
Published: March 2009

In this study, we aim for posture estimation that considers the influence of lighting changes. We propose an algorithm that considers a bad condition by using 3D data and 2D animation. The decrease of the gaze forward rate caused by the psychological condition and ensuing tiredness is a problem of safety driving. There is a technique for detecting looking away and looking down for a long time by estimation of the driver's face posture from the image as this method of settlement. However, the conventional technique uses images in the posture estimation, which has the problem of a strong influence on the lighting condition and the size of the database. This technique pays too much attention to lighting changes 3D data and texture information. Making the database solved these problems; the accuracy average obtained was 89% and the estimation speed was 6 f/s. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(2): 10–20, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10012
A Web page that provides map‐based interfaces for VRML/X3D content
Authors: Miyake Yoshihiro , Suzaki Kenichi , Araya Shinji
Published: March 2009

The electronic map is very useful for navigation in the VRML/X3D virtual environments. So far various map‐based interfaces have been developed. But they are lacking for generality because they have been separately developed for individual VRML/X3D contents, and users must use different interfaces for different contents. Therefore, we have developed a Web page that provides a common map‐based interface for VRML/X3D contents on the Web. Users access VRML/X3D contents via the Web page. The Web page automatically generates a simplified map by analyzing the scene graph of downloaded contents, and embeds the mechanism to link the virtual world and the map. An avatar is automatically created and added to the map, and both a user and its avatar are bidirectionally linked together. In the simplified map, obstructive objects are removed and the other objects are replaced by base boxes. This paper proposes the architecture of the Web page and the method to generate simplified maps. Finally, an experimental system is developed in order to show the improvement of frame rates by simplifying the map. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(2): 28–37, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10017
Vibration suppression control of redundant manipulator with flexible structure by considering nullspace motion
Authors: Sasaki Koji , Murakami Toshiyuki
Published: March 2009

A redundant manipulator is useful for posture control while maintaining the desired end‐effector position by using its redundancy. This makes it possible to perform agile motions such as obstacle avoidance while achieving the target task. However, as the number of degrees of freedom of motion increases, the stiffness of the redundant manipulator decreases, which induces unacceptable vibration in manipulator motion. To address this issue, this paper describes a strategy of vibration suppression by using a workspace observer and resonance ratio control based on nullspace control. The validity of the proposed approach is confirmed by simulations and experiments. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(2): 1–9, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10050
High‐accuracy modeling method for transmission line on surface acoustic wave substrates
Authors: Yamada Toru , Uriu Kazuhide , Jibu Toru , Seo Koji , Hashimoto Ken‐Ya , Yamaguchi Masatsune
Published: March 2009

A high‐accuracy modeling methodology for electrical characteristics of transmission electrodes on SAW substrates is established. In order to design SAW filter accurately, it is necessary to extract precise SAW material parameters from the measurement value of the reference SAW resonator. When measuring the SAW resonator, transmission lines are needed for feeding to contact probes. De‐embedding procedure, which removes the influence of transmission lines, is very important for accurate characterization of the SAW resonator.

In this paper, we apply the improved de‐embedding procedure using Short, Open, and Thru calibration patterns. The de‐embedded transmission line is separated in four parts and extracted the RLGC equivalent circuit model for each part. Furthermore, we derive the frequency characteristic of resistance element of the transmission line. Finally, de‐embedding the transmission line accurately, we can get intrinsic characteristic of the SAW resonator. This method must be very useful to extract SAW material parameters and we can design SAW filters more effectively. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(2): 49–55, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10230