bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Text S1 from High Prevalence of a Hotspot of Noncoding Somatic Mutations in Intron 6 of GPR126 in Bladder Cancer
Authors: Garinet Simon , Pignot Géraldine , Vacher Sophie , Le Goux Constance , Schnitzler Anne , Chemlali Walid , Sirab Nanor , Barry Delongchamps Nicolas , Zerbib Marc , Sibony Mathilde , Allory Yves , Damotte Diane , Bieche Ivan
Published: April 2023

Real time RT-PCR
Figure S6 from Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner
Authors: Valenzuela-Iglesias Alejandra , Burks Hope E. , Arnette Christopher R. , Yalamanchili Amulya , Nekrasova Oxana , Godsel Lisa M. , Green Kathleen J.
Published: April 2023

Supplemental Figure 6: Invadopodia formation and matrix degradation are reduced in UMSCC1 in the presence of Dsg1 in an Erbin-dependent fashion.
Figure S5 from Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner
Authors: Valenzuela-Iglesias Alejandra , Burks Hope E. , Arnette Christopher R. , Yalamanchili Amulya , Nekrasova Oxana , Godsel Lisa M. , Green Kathleen J.
Published: April 2023

Supplemental Figure 5: Erbin is required for Dsg1-dependent inhibition of invadopodia following EGF stimulation.
Supplementary Figure S3 from Differential Regulation of LET-7 by LIN28B Isoform–Specific Functions
Authors: Mizuno Rei , Chatterji Priya , Andres Sarah , Hamilton Kathryn , Simon Lauren , Foley Shawn W. , Jeganathan Arjun , Gregory Brian D. , Madison Blair , Rustgi Anil K.
Published: April 2023

LIN28B-S in Huh7.5 cells
Supplementary methods and Supplementary FigS1-6 from c-MYC Drives Breast Cancer Metastasis to the Brain, but Promotes Synthetic Lethality with TRAIL
Authors: Lee Ho Yeon , Cha Junghwa , Kim Seon Kyu , Park Jun Hyung , Song Ki Hoon , Kim Pilnam , Kim Mi-Young
Published: April 2023

S1. Elevated c-MYC activity in MCF7-BrM promotes brain metastasis (related to Fig 1) S2. C-MYC regulates tumor sphere circularity and invasiveness in a HA-collagen matrix (related to Fig 2) S3. c-MYC-mediated recruitment of RAW cells (related to Fig 3) S4. qRT-PCR analysis of c-MYC-regulated genes (related to Fig 4) S5. Association of c-MYC and MYC-BrMFS with BrMFS in the MSK82 dataset (related to Fig 5) S6. BrM-BCCs exhibit elevated TRAIL sensitivity (related to Fig 6)
Supplemental Figure 3 from TGFβ-Induced Lung Cancer Cell Migration Is NR4A1-Dependent
Authors: Hedrick Erik , Mohankumar Kumaravel , Safe Stephen
Published: April 2023

PKA inhibition affects nuclear export of NR4A1 in A549 cells.
Figure S1 from Population-dependent Intron Retention and DNA Methylation in Breast Cancer
Authors: Kim Dongwook , Shivakumar Manu , Han Seonggyun , Sinclair Michael S. , Lee Young-Ji , Zheng Yonglan , Olopade Olufunmilayo I. , Kim Dokyoon , Lee Younghee
Published: April 2023

Supplementary Figure S1. Study design overview. Step 1 and 2 involved to align reads onto human genome using TopHat and identify retained intron events between European-American (EA) and African-American (AA) using rMATS, respectively. Step 3 and 4 was to identify statistically significant retained introns whose PSI "percent splice in", value are less than p-value 0.05 and false discovery rate (FDR) 0.3. If PSI differences between AA and EA patients were equal to or greater than 10%, differentially expressed IRs between AA and EA patients were identified; otherwise, events with less than 10% difference in PSI were identified as a commonly expressed. Step 5 integrated DNA methylation status (beta-value) in a retained intron, its upstream and downstream exons with PSI values of given retained intron and therefore, estimated the correlation between methylation and retained introns using regression analysis of covariance (ANCOVA) models in R between subtypes. Step 6, we then extracted the vital status and overall survival time of the patients for all subtypes, Luminal A and Basal-like subtype. We performed Kaplan Meier overall survival analysis between AA and EA groups.
Supplemental Table 4 from Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion
Authors: Tang Jessica , Pulliam Nicholas , Özeş Ali , Buechlein Aaron , Ding Ning , Keer Harold , Rusch Doug , O'Hagan Heather , Stack M. Sharon , Nephew Kenneth P.
Published: April 2023

RNA-seq genes_FC 1.2, P 0.05
Supplemental Table 3 from Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion
Authors: Tang Jessica , Pulliam Nicholas , Özeş Ali , Buechlein Aaron , Ding Ning , Keer Harold , Rusch Doug , O'Hagan Heather , Stack M. Sharon , Nephew Kenneth P.
Published: April 2023

Mecap-Seq, RNA-seq, and Integrated IPA pathways
Supplementary Figure 1 from Daxx Functions Are p53-Independent In Vivo
Authors: Wasylishen Amanda R. , Estrella Jeannelyn S. , Pant Vinod , Chau Gilda P. , Lozano Guillermina
Published: April 2023

Immunohistochemical staining of tumors
Supplementary Figure S2 from A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance
Authors: Olender Jacqueline , Wang Bi-Dar , Ching Travers , Garmire Lana X. , Garofano Kaitlin , Ji Youngmi , Knox Tessa , Latham Patricia , Nguyen Kenneth , Rhim Johng , Lee Norman H.
Published: April 2023

S2. Common FGFR3 alterations by cancer type.
Figure S1 from Elevated miR-182-5p Associates with Renal Cancer Cell Mitotic Arrest through Diminished MALAT-1 Expression
Authors: Kulkarni Priyanka , Dasgupta Pritha , Bhat Nadeem S. , Shahryari Varahram , Shiina Marisa , Hashimoto Yutaka , Majid Shahana , Deng Guoren , Saini Sharanjot , Tabatabai Z. Laura , Yamamura Soichiro , Tanaka Yuichiro , Dahiya Rajvir
Published: April 2023

Figure S1 depicts the location of CpG islands in promoter region of miR-182-5p
Table S4 from CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP
Authors: Moure Casey J. , Diplas Bill H. , Chen Lee H. , Yang Rui , Pirozzi Christopher J. , Wang Zhaohui , Spasojevic Ivan , Waitkus Matthew S. , He Yiping , Yan Hai
Published: April 2023

Oligonucleotides Used in Study
Table S3 from CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP
Authors: Moure Casey J. , Diplas Bill H. , Chen Lee H. , Yang Rui , Pirozzi Christopher J. , Wang Zhaohui , Spasojevic Ivan , Waitkus Matthew S. , He Yiping , Yan Hai
Published: April 2023

Conserved Demethylations
Supplementary Figure S1 from PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF
Authors: Sulkowski Parker L. , Scanlon Susan E. , Oeck Sebastian , Glazer Peter M.
Published: April 2023

Additional Data for Patient Derived Melanoma Cells and Luciferase Reporter Assays
Table S2 from CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP
Authors: Moure Casey J. , Diplas Bill H. , Chen Lee H. , Yang Rui , Pirozzi Christopher J. , Wang Zhaohui , Spasojevic Ivan , Waitkus Matthew S. , He Yiping , Yan Hai
Published: April 2023

Differentially Methylated Probes Parental vs. Edited Clones or Parental vs. Unedited Clones
Table S1 from CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP
Authors: Moure Casey J. , Diplas Bill H. , Chen Lee H. , Yang Rui , Pirozzi Christopher J. , Wang Zhaohui , Spasojevic Ivan , Waitkus Matthew S. , He Yiping , Yan Hai
Published: April 2023

Exome Seq for IMA and 08-0537
Supplementary Figure 4 from Ovarian Tumor Cell Expression of Claudin-4 Reduces Apoptotic Response to Paclitaxel
Authors: Breed Christopher , Hicks Douglas A. , Webb Patricia G. , Galimanis Carly E. , Bitler Benjamin G. , Behbakht Kian , Baumgartner Heidi K.
Published: April 2023

Apoptotic response of cells with claudin-4 expression knocked down.
Figure S3 from HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors
Authors: VandeKopple Matthew J. , Wu Jinghai , Auer Erich N. , Giaccia Amato J. , Denko Nicholas C. , Papandreou Ioanna
Published: April 2023

LD staining during LD turnover inhibition in HCT116
Figure S2 from HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors
Authors: VandeKopple Matthew J. , Wu Jinghai , Auer Erich N. , Giaccia Amato J. , Denko Nicholas C. , Papandreou Ioanna
Published: April 2023

HCT116 LC/MS lipidomics
Supplementary Table S6 from Nomogram Integrating Genomics with Clinicopathologic Features Improves Prognosis Prediction for Colorectal Cancer
Authors: Xiong Yongfu , You Wenxian , Hou Min , Peng Linglong , Zhou He , Fu Zhongxue
Published: April 2023

Univariate and multivariate analyses of prognostic factors for disease-free survival
Supplementary Table 3 from Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy
Authors: Octeau David , Kessous Roy , Klein Kathleen , Kogan Liron , Pelmus Manuella , Ferenczy Alex , Greenwood Celia M.T. , Van Kempen Leon C. , Salvador Shannon , Lau Susie , Tonin Patricia N. , Yasmeen Amber , Gotlieb Walter H.
Published: April 2023

Gene expression values
Supplemental Tables 1-4 from Identification of Targetable Recurrent MAP3K8 Rearrangements in Melanomas Lacking Known Driver Mutations
Authors: Lehmann Brian D. , Shaver Timothy M. , Johnson Douglas B. , Li Zhu , Gonzalez-Ericsson Paula I. , Sánchez Violeta , Shyr Yu , Sanders Melinda E. , Pietenpol Jennifer A.
Published: April 2023

Supplemental Table 1. MAP3K8 qPCR positional primers Supplemental Table 2. TCGA SKCM dataset clinical and expression data. Supplemental Table 3. Rockland Wistar Institution Melanoma Cell Lines Mutation Staus Supplemental Table 4. MAP3K8 break-apart FISH scoring of Vanderbilt TMA
Supplementary Figure S2 from ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1
Authors: Tyagi Nikhil , Deshmukh Sachin K. , Srivastava Sanjeev K. , Azim Shafquat , Ahmad Aamir , AL-Ghadhban Ahmed , Singh Ajay P. , Carter James E. , Wang Bin , Singh Seema
Published: April 2023

Overexpression of cyclin D1 in ETV4-silenced cells rescued the inhibitory effect of ETV4-silencing on clonogenic potential of PC cells.
Supplemental Figure 1. from lincRNA-RoR and miR-145 Regulate Invasion in Triple-Negative Breast Cancer via Targeting ARF6
Authors: Eades Gabriel , Wolfson Benjamin , Zhang Yongshu , Li Qinglin , Yao Yuan , Zhou Qun
Published: April 2023

Supplemental Figure 1. MiR-145 expression data from The Cancer Genome Atlas comparing breast tumors and normal breast tissue as analyzed using starBase V2.0.
Gil dSupplementary Figure 4 from Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma
Authors: Gil del Alcazar Carlos Rodrigo , Todorova Pavlina Krasimirova , Habib Amyn A. , Mukherjee Bipasha , Burma Sandeep
Published: April 2023

Supplemental Figure 4. A. Primary (483 and 484) and recurrent (419 and 481) cultures were pulsed with 50 nM CPT for 2 hours, and fixed 2 hours later. Cells were immunofluorescence- stained for γH2AX (green) and Rad51 foci (red) and imaged at 40X magnification. Nuclei are stained with DAPI (blue). Representative images are shown. The proportion of DSBs (marked by γH2AX foci) undergoing homologous recombination repair (marked by Rad51 foci) was determined by scoring γH2AX and Rad51 foci. The ratio of Rad51 and γH2AX foci (y-axis) is plotted against the respective cell line (x-axis). Error bars, S.E.M. B. Primary (483 and 484) and recurrent (419 and 481) cultures were labeled with BrdU for one cell cycle, pulsed with 50 nM CPT for 2 hours, and fixed 2 hours later. Cells were immunofluorescence-stained for BrdU foci (red), and imaged at 40X magnification to assess DNA end resection. Nuclei are stained with DAPI (blue). Representative images are shown. Average number of BrdU foci per nucleus (y-axis) is plotted against the respective cell line (x-axis). Error bars, S.E.M.
Data Supplement from The Lipid Kinase PI4KIIIβ Is Highly Expressed in Breast Tumors and Activates Akt in Cooperation with Rab11a
Authors: Morrow Anne A. , Alipour Mohsen Amir , Bridges Dave , Yao Zemin , Saltiel Alan R. , Lee Jonathan M.
Published: April 2023

Supplementary Figure 7
Table S5 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Authors: Mo Allen , Jackson Stephen , Varma Kamini , Carpino Alan , Giardina Charles , Devers Thomas J. , Rosenberg Daniel W.
Published: April 2023

Differentially expressed genes between normal and ACF stroma.
Figure S2 from PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling
Authors: Peng Xing-Si , Yang Jun-Ping , Qiang Yuan-Yuan , Sun Rui , Cao Yun , Zheng Li-Sheng , Peng Li-Xia , Lang Yan-Hong , Mei Yan , Li Chang-Zhi , Meng Dong-Fang , Liu Zhi-Jie , Wang Ming-Dian , Zhou Fang-Jian , Huang Bi-Jun , Qian Chao-Nan
Published: April 2023

Suppression of PTPN3 increased the cell colony numbers. Representative micrographs and quantification of crystal violet stained cells from 3 independent experiments. Columns, average of three independent experiments; bars, SD. *P < 0.05, **P < 0.01, Student t test.
Table S3 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Authors: Mo Allen , Jackson Stephen , Varma Kamini , Carpino Alan , Giardina Charles , Devers Thomas J. , Rosenberg Daniel W.
Published: April 2023

Differentially expressed genes between KRAS or BRAF mutant ACF and APC mutant ACF epithelium.
Supplementary Figure 5 from Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins
Authors: Maachani Uday Bhanu , Kramp Tamalee , Hanson Ryan , Zhao Shuping , Celiku Orieta , Shankavaram Uma , Colombo Riccardo , Caplen Natasha J. , Camphausen Kevin , Tandle Anita
Published: April 2023

Supplementary Figure 5. To assay nonhomologous end joining (NHEJ), U251 DR-GFP cells were transfected with pCBAScel vector and harvested at 48 hours after indicated treatments. Genomic DNA was harvested for PCR amplification using DR-GFP primers, followed by I-Scel+Bcgl enzyme digestion and PCR products were subjected to gel electrophoresis.
Supplementary Figure 4 from Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins
Authors: Maachani Uday Bhanu , Kramp Tamalee , Hanson Ryan , Zhao Shuping , Celiku Orieta , Shankavaram Uma , Colombo Riccardo , Caplen Natasha J. , Camphausen Kevin , Tandle Anita
Published: April 2023

Supplementary Figure 4. To assay homologous recombination (HR), U251 DR-GFP cells were transfected with pCBAScel vector and harvested at 48 hours after indicated treatments. GFP+ve cells representing HR repair events were determined by flow cytometry and PCR based assays.
Supplemental Materials and Methods, Supplementary Tables 1 and 2 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
Authors: Dambal Shweta , Alfaqih Mahmoud , Sanders Sergio , Maravilla Erick , Ramirez-Torres Adela , Galvan Gloria C. , Reis-Sobreiro Mariana , Rotinen Mirja , Driver Lucy M. , Behrove Matthew S. , Talisman Tijana Jovanovic , Yoon Junhee , You Sungyong , Turkson James , Chi Jen-Tsan , Freeman Michael R. , Macias Everardo , Freedland Stephen J.
Published: April 2023

Supplemental Table 1. Adjusted p-Values of SH-4-54 and 27HC (10 uM) single and combination treatment by 2Way ANOVA with Tukey's Multiple Comparisons Posthoc Statistical Analysis Supplemental Table 2. Adjusted p-Values of C188-9 and 27HC (10 uM) single and combination treatment by 2Way ANOVA with Tukey's Multiple Comparisons Posthoc Statistical Analysis
Figure S5 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
Authors: Dambal Shweta , Alfaqih Mahmoud , Sanders Sergio , Maravilla Erick , Ramirez-Torres Adela , Galvan Gloria C. , Reis-Sobreiro Mariana , Rotinen Mirja , Driver Lucy M. , Behrove Matthew S. , Talisman Tijana Jovanovic , Yoon Junhee , You Sungyong , Turkson James , Chi Jen-Tsan , Freeman Michael R. , Macias Everardo , Freedland Stephen J.
Published: April 2023

Correlation studies in AR high and AR low patient samples
Supplementary Data from Exposure of Patient-Derived Mesenchymal Stromal Cells to TGFB1 Supports Fibrosis Induction in a Pediatric Acute Megakaryoblastic Leukemia Model
Authors: Hack Theresa , Bertram Stefanie , Blair Helen , Börger Verena , Büsche Guntram , Denson Lora , Fruth Enrico , Giebel Bernd , Heidenreich Olaf , Klein–Hitpass Ludger , Kollipara Laxmikanth , Sendker Stephanie , Sickmann Albert , Walter Christiane , von Neuhoff Nils , Hanenberg Helmut , Reinhardt Dirk , Schneider Markus , Rasche Mareike
Published: April 2023

Figure S1. Cells isolated from bone marrow aspirates of ML-DS and AMKL patients as well HDs fulfilled the minimal ISCT criteria of MSCs. Figure S2. Unsupervised hierarchical clustering of MSCs without grouping according to their entities. Figure S3. Gene set enrichment analysis plots for overexpressed hallmark gene sets associated with proliferation in the disease-derived MSCs compared to HD-MSCs. Table S1: Clinical data of patients and HDs. Table S2: Results of immunphenotypic characterisation. Table S3: Overview of all generated ossicle-like structures. Table S4: TaqMan probes used in RT-PCR assays. Table S5: Anti-human primary antibodies used for immunohistochemical staining.
Figure S2 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
Authors: Dambal Shweta , Alfaqih Mahmoud , Sanders Sergio , Maravilla Erick , Ramirez-Torres Adela , Galvan Gloria C. , Reis-Sobreiro Mariana , Rotinen Mirja , Driver Lucy M. , Behrove Matthew S. , Talisman Tijana Jovanovic , Yoon Junhee , You Sungyong , Turkson James , Chi Jen-Tsan , Freeman Michael R. , Macias Everardo , Freedland Stephen J.
Published: April 2023

This figure depicts cholesterol clusters after 27HC treatment
Figure S1 from c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein
Authors: Bunda Severa , Heir Pardeep , Li Annie Si Cong , Mamatjan Yasin , Zadeh Gelareh , Aldape Kenneth
Published: April 2023

Figure S1 shows that Dasatinib a selective Src kinase inhibitor only affects the viability of GBM derived cells with elevated Src kinase activity.
Supplementary Figure 1 from Aquaporin-9, Mediated by IGF2, Suppresses Liver Cancer Stem Cell Properties via Augmenting ROS/β-Catenin/FOXO3a Signaling
Authors: Zheng Xi , Li Chuanfei , Yu Keqi , Shi Shasha , Chen Hongyu , Qian Yanzhi , Mei Zhechuan
Published: April 2023

Supplementary Figure 1 shows that spheroid formation assays were performed in MHCC97H and Huh7 cells.
Figure S3 from DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 Status
Authors: Kataoka Yuki , Iimori Makoto , Fujisawa Ryo , Morikawa-Ichinose Tomomi , Niimi Shinichiro , Wakasa Takeshi , Saeki Hiroshi , Oki Eiji , Miura Daisuke , Tsurimoto Toshiki , Maehara Yoshihiko , Kitao Hiroyuki
Published: April 2023

Data related to Fig. 3.
SUPPLEMENTARY DATA from Downregulation of the Deiminase PADI2 Is an Early Event in Colorectal Carcinogenesis and Indicates Poor Prognosis
Authors: Cantariño Neus , Musulén Eva , Valero Vanesa , Peinado Miquel Angel , Perucho Manuel , Moreno Victor , Forcales Sònia-Vanina , Douet Julien , Buschbeck Marcus
Published: April 2023

Contains supplemental methods and materials, 2 figures, a table and supplemental references. Figure 1. Preliminary evidence suggesting that PADI2 re-expression in colon cancer cells conveys sensitivity to calcium treatment. Figure S2. The association of PADI2 levels in adjacent mucosa is independent of inflammation and immune cell infiltration. Table S1. Inflammatory hallmark gene set (extracted from MSigDB).
Supplementary Data from A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells
Authors: Song Jing , Du Zhanwen , Ravasz Mate , Dong Bohan , Wang Zhenghe , Ewing Rob M.
Published: April 2023

Supplementary proteomics data
Supplementary Table 1 from Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial–Mesenchymal Transition–like Process and 22q Loss
Authors: Stacchiotti Silvia , Astolfi Annalisa , Gronchi Alessandro , Fontana Andrea , Pantaleo Maria A. , Negri Tiziana , Brenca Monica , Tazzari Marcella , Urbini Milena , Indio Valentina , Colombo Chiara , Radaelli Stefano , Brich Silvia , Dei Tos Angelo P. , Casali Paolo G. , Castelli Chiara , Dagrada Gian Paolo , Pilotti Silvana , Maestro Roberta
Published: April 2023

Clinical/pathologic characteristics of the patients from whom the tissue samples molecularly profiled were derived; bold/underlined type indicates the tumor tissue from which the sample for the molecular analysis was derived.
Supplementary Material and methods from Hepatitis B Virus X Protein Induces RHAMM-Dependent Motility in Hepatocellular Carcinoma Cells via PI3K–Akt–Oct-1 Signaling
Authors: Liu Yu-Chin , Lu Li-Feng , Li Chia-Jung , Sun Nian-Kang , Guo Jing-You , Huang Ya-Hui , Yeh Chau-Ting , Chao Chuck C.-K.
Published: April 2023

Additional materials and methods information
Supplementary Fig. S1 from Hepatitis B Virus X Protein Induces RHAMM-Dependent Motility in Hepatocellular Carcinoma Cells via PI3K–Akt–Oct-1 Signaling
Authors: Liu Yu-Chin , Lu Li-Feng , Li Chia-Jung , Sun Nian-Kang , Guo Jing-You , Huang Ya-Hui , Yeh Chau-Ting , Chao Chuck C.-K.
Published: April 2023

The regulatory effect of Oct-1 on RHAMM expression.
Supplementary Figure Legends from miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1
Authors: Sakaguchi Masazumi , Hisamori Shigeo , Oshima Nobu , Sato Fumiaki , Shimono Yohei , Sakai Yoshiharu
Published: April 2023

Supplementary Figure Legends
Figure S9 from CD44 Regulates Formation of Spheroids and Controls Organ-Specific Metastatic Colonization in Epithelial Ovarian Carcinoma
Authors: Sacks Suarez Joelle , Gurler Main Hilal , Muralidhar Goda G. , Elfituri Osama , Xu Hao-Liang , Kajdacsy-Balla Andre A. , Barbolina Maria V.
Published: April 2023

SUPPLEMENTARY FIGURE 9. The parental and CD44-/- ES2 cells colonize intra- and retroperitoneal sites with different efficiency.
Figure S10 from CD44 Regulates Formation of Spheroids and Controls Organ-Specific Metastatic Colonization in Epithelial Ovarian Carcinoma
Authors: Sacks Suarez Joelle , Gurler Main Hilal , Muralidhar Goda G. , Elfituri Osama , Xu Hao-Liang , Kajdacsy-Balla Andre A. , Barbolina Maria V.
Published: April 2023

SUPPLEMENTARY FIGURE 10. Silencing of CD44 does not affect cell morphology (A), expression of mesenchymal markers (B), cell migration (C,D), or Matrigel invasion.
Figure S1, S2, S3, and S4 from CD44 Regulates Formation of Spheroids and Controls Organ-Specific Metastatic Colonization in Epithelial Ovarian Carcinoma
Authors: Sacks Suarez Joelle , Gurler Main Hilal , Muralidhar Goda G. , Elfituri Osama , Xu Hao-Liang , Kajdacsy-Balla Andre A. , Barbolina Maria V.
Published: April 2023

SUPPLEMENTARY FIGURE 1. mRNA expression of CD44 isoforms (total, standard, V2, V3, V4, V5, V6, V7, V8, V9, V10) in epithelial ovarian carcinoma cell lines. SUPPLEMENTARY FIGURE 2. mRNA expression of CD44 isoforms (total, standard, V2, V6, V8) in specimens of serous ovarian carcinoma. SUPPLEMENTARY FIGURE 3. mRNA expression of CD44 isoforms (total, standard, V2, V6, V8) in specimens of endometrioid ovarian carcinoma. SUPPLEMENTARY FIGURE 4. mRNA expression of CD44 isoforms (total, standard, V2, V6, V8) in specimens of mucinous ovarian carcinoma.
Supplementary Figures 1-5 and Tables 1-3 from Signals from the Metastatic Niche Regulate Early and Advanced Ovarian Cancer Metastasis through miR-4454 Downregulation
Authors: Dasari Subramanyam , Pandhiri Taruni , Grassi Tommaso , Visscher Daniel W. , Multinu Francesco , Agarwal Komal , Mariani Andrea , Shridhar Viji , Mitra Anirban K.
Published: April 2023

S1. The top pathways regulated by the 26 common microRNAs and miR-4454 expression in a panel of cells. S2. Validation of miR-4454 overexpression and inhibition in OC cells. S3. Functional effects of stable overexpression of miR-4454 in OVCAR8. S4. Genes and pathways regulated by miR-4454. S5. miR-4454 target validation. Supplementary Table 1 : Clinical characteristics of the 42 epithelial ovarian cancer patients. Supplementary Table 2: List of microRNAs downregulated in both OC patient primary tumor vs. matched metastasis and in Kuramochi/OVCAR4/OVCAR8 cells on 3D omental culture vs. control. Supplementary Table 3: Subset of miR-4454 targets with cancer relevant functions based on a literature search.
Supplementary Figures 1-10 from Combination Lenalidomide/Bortezomib Treatment Synergistically Induces Calpain-Dependent Ikaros Cleavage and Apoptosis in Myeloma Cells
Authors: Ganesan Saravanan , Palani Hamenth Kumar , Balasundaram Nithya , David Sachin , Devasia Anup J. , George Biju , Mathews Vikram
Published: April 2023

S1. Combination of lenalidomide (1uM) and bortezomib (different concentrations) induces apoptosis in myeloma cell lines (MM.1S and U266) compared to bortezomib alone treated cells (n=3) at the end of 48 hours. S2. Representative Immunoblot showing induction of apoptosis in MM.1S cell line upon treatment with lenalidomide (1uM) and bortezomib (5nM), lysates were collected the end of 24 and 48 hours post treatment with drugs (n=3). The proteins analysed were mentioned in the image. S3. a) Immunoblot showing that the combination of lenalidomide and bortezomib degraded IKZF1 in U266 cell line (n=3). b) Immunofluorescence assays showing degradation of IKZF1 in U266 cell line upon treatment with Lenalidomide and bortezomib (n=3). S4. Immunoprecipitation of Ubiquitin after treatment with lenalidomide (1uM) and bortezomib (5nM) revealed an interaction with IKZF1 at 8 hours. S5. Inhibition of autophagy by hydroxycholoroquine (HCQ) and bafilomycin A1 (BAFA1) in MM1.S cell line was confirmed using cyto-ID stain, where accumulation of autophagosome was observed (n=3) which was further confirmed by western blot (n=3). S6. Inhibition of autophagy by hydroxycholoroquine (HCQ) and bafilomycin A1 (BAFA1) did not inhibit the degradation of IKZF1 in U266 cell line (n=3). S7. Inhibition of calpain and caspase by PD150606 and zVAD.fmk inhibited the degradation of IKZF1 in U266 cell line (n=3). S8. Inhibition of calpain and chelation of calcium resulted in inhibition of PARP cleavage and IKZF3 degradation in MM1.S cell line (n=3) at the end of 24 hours of drug treatments. S9. Immunoblot representing modulation of calcium flux with ionomycin in MM.1S cell line enhanced IKZF1 degradation only in Ionomycin alone or in combination with LEN treated cells for 12 hours (n=3). S10. Viability of MM1.S cell line at post LEN (1uM) and BTZ (5nM) treatment after 48 hours (n=3). Viability was assessed by Annexin V- and 7 AAD - viability assay.
Supplementary Table S5 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Correlation between Karpf 450K and Karpf Methyl-Seq.
Supplementary Table S4 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Karpf 450K FTE and OSE vs. Bowtell 450K FTE methylomes.
Supplementary Table S2 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

DNA methylome sequencing parameters and results.
Supplemental Figures 1-5 from LEF1 Targeting EMT in Prostate Cancer Invasion Is Regulated by miR-34a
Authors: Liang Jiaqian , Li Yirong , Daniels Garrett , Sfanos Karen , De Marzo Angelo , Wei Jianjun , Li Xin , Chen Wenqiang , Wang Jinhua , Zhong Xuelin , Melamed Jonathan , Zhao Jun , Lee Peng
Published: April 2023

Supplemental Figures 1-5. Supplemental Figure 1. Expression levels of miR-34a, miR-1260, miR-206, miR-93, miR-324-3P andmiR-324-5P in four (LNCaP, LNCaP-LEF1, LNCaP-AI, LNCaP-AILEF1shRNA) PCa cell lines by real time qRT-PCR. U6 was used for normalization. Supplemental Figure 2. Conservation of the predicated miR-34a binding sites in the LEF1 3'UTR among species Supplemental Figure 3. Schematic diagram of luciferase constructs used for testing miR34a repression of LEF1 Supplemental Figure 4. Reciprocol negative regulation of miR34a by LEF1. There is an decrease in miR34a expression in cell line with high levels of LEF1. Supplemetal Figure 5. Schematic diagram delinateing the miR34a-LEF1-EMT axis in regulating PCa invasion.
Figure S5 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Methylation of HOX genes in HGSC, FTE, and OSE.
Figure S3 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

PAX8 and MSLN methylation in HGSC, FTE, and OSE.
Supplemental Figure 6 from Identification of TRIML2, a Novel p53 Target, that Enhances p53 SUMOylation and Regulates the Transactivation of Proapoptotic Genes
Authors: Kung Che-Pei , Khaku Sakina , Jennis Matthew , Zhou Yan , Murphy Maureen E.
Published: April 2023

Figure S6. TRIML2 does not affect SUMO1- or Ubiquitin modification of p53; TRIML2 is the only TRIM protein differentially regulated by codon 72 polymorphism of p53.
Supplemental Figure 3 from Identification of TRIML2, a Novel p53 Target, that Enhances p53 SUMOylation and Regulates the Transactivation of Proapoptotic Genes
Authors: Kung Che-Pei , Khaku Sakina , Jennis Matthew , Zhou Yan , Murphy Maureen E.
Published: April 2023

Figure S3. TRIML2 contributes to the different apoptotic potential between P72 and R72.
Supplemental Figure 2 from Identification of TRIML2, a Novel p53 Target, that Enhances p53 SUMOylation and Regulates the Transactivation of Proapoptotic Genes
Authors: Kung Che-Pei , Khaku Sakina , Jennis Matthew , Zhou Yan , Murphy Maureen E.
Published: April 2023

Figure S2. p53-dependent TRIML2 induction is increased in R72 cells and positively regulates p53 activation and apoptosis.
Supplemental Figure 1 from Association of HO-1 and BRCA1 Is Critical for the Maintenance of Cellular Homeostasis in Prostate Cancer
Authors: Labanca Estefanía , De Luca Paola , Gueron Geraldine , Paez Alejandra , Moiola Cristian P. , Massillo Cintia , Porretti Juliana , Giudice Jimena , Zalazar Florencia , Navone Nora , Vazquez Elba , De Siervi Adriana
Published: April 2023

S1A. Cross-cancer alteration summary for BRCA1, HMOX1, NFE2L2 (9 studies / 3 genes). S1B. mRNA co-expression of gene pairs BRCA1/NRF2 and HO-1/NRF2 in 109 samples (Broad/Cornell, Nature Genetics 2012) and 56 samples (Broad/Cornell, Cell 2013), respectively. Perason's correlation and Spearman's correlation scores are shown. S1C. mRNA co-expression of gene pairs HO-1/NRF2 in 103 samples (MSKCC, Cancer Cell 2010). Perason's correlation and Spearman's correlation scores are shown. S1D. mRNA co-expression of gene pairs HO-1/NRF2 in 103 samples (MSKCC, Cancer Cell 2010), given by mRNA expression Z-scores vs Normals.Perason's correlation and Spearman's correlation scores are shown. S1E. mRNA co-expression of gene pairs HO-1/BRCA1 in 103 samples (MSKCC, Cancer Cell 2010), given by mRNA expression outliers. Perason's correlation and Spearman's correlation scores are shown.
Supplementary Figure 5 from Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
Authors: Jane Esther P. , Premkumar Daniel R. , Thambireddy Swetha , Golbourn Brian , Agnihotri Sameer , Bertrand Kelsey C. , Mack Stephen C. , Myers Max I. , Chattopadhyay Ansuman , Taylor D. Lansing , Schurdak Mark E. , Stern Andrew M. , Pollack Ian F.
Published: April 2023

Supplemental Figure 5. Drug naive or panobinostat and bortezomib resistant (Pano + Bort) U87 or SJG 2 cells were either non-target siRNA (NT siRNA) or QPRT siRNA-2 as described in the Materials and Methods.
Supplementary Table 1 from Bone Marrow Microenvironment Niche Regulates miR-221/222 in Acute Lymphoblastic Leukemia
Authors: Moses Blake S. , Evans Rebecca , Slone William L. , Piktel Debbie , Martinez Ivan , Craig Michael D. , Gibson Laura F.
Published: April 2023

Excel sheet showing mean signal intensities and p-values of SUP-B15 ALL cells cultured in media only or co-cultured with BMSC. Statistics were done as follows: Data were analyzed by first subtracting the background and then normalizing the signals using a LOWESS filter (Locally-weighted Regression) (2). For two color experiments, the ratio of the two sets of detected signals (log2 transformed, balanced) and p-values of the t-test were calculated; differentially detected signals were those with less than 0.01 p-values.
Supplementary Table 6 from Tumor Cell–Derived MMP3 Orchestrates Rac1b and Tissue Alterations That Promote Pancreatic Adenocarcinoma
Authors: Mehner Christine , Miller Erin , Khauv Davitte , Nassar Aziza , Oberg Ann L. , Bamlet William R. , Zhang Lizhi , Waldmann Jens , Radisky Evette S. , Crawford Howard C. , Radisky Derek C.
Published: April 2023

XLSX file - 609K, Supplemental Table 6. Overlap of genes between MMP-3-treated cells and invasive/metastatic pancreatic cancer cells.
Supplementary Table 1 from Tumor Cell–Derived MMP3 Orchestrates Rac1b and Tissue Alterations That Promote Pancreatic Adenocarcinoma
Authors: Mehner Christine , Miller Erin , Khauv Davitte , Nassar Aziza , Oberg Ann L. , Bamlet William R. , Zhang Lizhi , Waldmann Jens , Radisky Evette S. , Crawford Howard C. , Radisky Derek C.
Published: April 2023

PDF file - 110K, Supplemental Table 1. Analysis of Patient Stage vs MMP3 & Rac1b Staining Intensity.
Supplementary Tables S1-6 from Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome
Authors: Poulos Rebecca C. , Thoms Julie A.I. , Shah Anushi , Beck Dominik , Pimanda John E. , Wong Jason W.H.
Published: April 2023

Supplementary Tables S1-6. Table S1. Mutation coordinates and associated genes for potential putative promoter mutations identified in COLO-829. Table S2. Number of promoter and total mutations in each of 34 whole-genome sequenced cutaneous melanoma samples available from TCGA. Table S3. Details of polymerase chain reaction (PCR) amplification and genomic DNA used for reporter constructs. Table S4. Base calls at each mutation site for the four COLO-829 promoter mutations with changes observed in mutant promoter activity from wild-type by reporter assays. Table S5. Single nucleotide polymorphisms (SNPs) present within reporter constructs. Table S6. Primer sequences used for each candidate gene in polymerase chain reaction (PCR) and quantitative polymerase chain reaction (qPCR) experiments.
Supplementary Methods and Legends from Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome
Authors: Poulos Rebecca C. , Thoms Julie A.I. , Shah Anushi , Beck Dominik , Pimanda John E. , Wong Jason W.H.
Published: April 2023

Supplementary Methods and Legends
supplemental figure 6 from SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism
Authors: Hoang Bao , Shi Yijiang , Frost Patrick J. , Mysore Veena , Bardeleben Carolyne , Lichtenstein Alan
Published: April 2023

Suppl fig 6: Combination indices (CIs) and fraction affected in 8226 cells treated with either bortezomib +/- SGK inhibitor (in A) or Staurosporine +/- SGK inhibitor (in B). CIs determined from apoptosis data of 4 independent experiments using mean values.
Supplementary Figure 1 from Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome
Authors: Poulos Rebecca C. , Thoms Julie A.I. , Shah Anushi , Beck Dominik , Pimanda John E. , Wong Jason W.H.
Published: April 2023

Supplementary Figure 1. Validation of COLO-829 putative promoter region and mutation designation.
supplemental figure 2 from SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism
Authors: Hoang Bao , Shi Yijiang , Frost Patrick J. , Mysore Veena , Bardeleben Carolyne , Lichtenstein Alan
Published: April 2023

Suppl fig 2 ) MM1.S or OPM-2 MM cells stably transfected with empty vector (ev), wild type AKT (akt), phosphomimetic AKT, (akt473d), wild type SGK (sgk) or Phosphomimetic SGK (sgk422d), challenged with pp242 (left panels) or torin (right panels) followed by apoptosis assay. Data are percent apoptosis above control (no drug) mean+/-SE, n=5. Asterixes denote significantly decreased apoptosis (p<0.05)versus empty vector cells.
Supplementary Table 2 from Convergent and Divergent Cellular Responses by ErbB4 Isoforms in Mammary Epithelial Cells
Authors: Wali Vikram B. , Haskins Jonathan W. , Gilmore-Hebert Maureen , Platt James T. , Liu Zongzhi , Stern David F.
Published: April 2023

XLSX file - 42KB, Canonical pathways altered by FL and ICD ERBB4.
Supplementary Figure 3 from Convergent and Divergent Cellular Responses by ErbB4 Isoforms in Mammary Epithelial Cells
Authors: Wali Vikram B. , Haskins Jonathan W. , Gilmore-Hebert Maureen , Platt James T. , Liu Zongzhi , Stern David F.
Published: April 2023

PDF file - 2955KB, IPA analysis.
Supplementary Figure 1 from Convergent and Divergent Cellular Responses by ErbB4 Isoforms in Mammary Epithelial Cells
Authors: Wali Vikram B. , Haskins Jonathan W. , Gilmore-Hebert Maureen , Platt James T. , Liu Zongzhi , Stern David F.
Published: April 2023

PDF file - 135KB, Validation of transcriptional microarray results by qRT-PCR in MCF10A and T47D cells. A) Full-length (FL) and ICD (B) ERBB4 microarray gene validation in MCF10A cells. Total RNA was isolated from Vector-MCF10A, CYT-1 MCF10A and CYT-2 MCF10A cells after 2h exposure to 100ng/ml NRG1 (Vector+, CYT-1+ and CYT-2+) in serum-free OptiMEM media, or from ICD Vector, CYT-1 and CYT-2 MCF10A cells grown in serum containing medium. C) T47D ERBB4 3'-UTR KD, pInducer20 ERBB4 validation of genes from MCF10A microarray in a luminal cell background. T47D cells were starved for 24hrs and stimulated with NRG1 for 2hrs in the presence of DOX (24hrs). Graphs show relative expression of genes as measured by qRT-PCR normalized to GAPDH.
Data Supplement from Decreased Expression of Cystathionine β-Synthase Promotes Glioma Tumorigenesis
Authors: Takano Naoharu , Sarfraz Yasmeen , Gilkes Daniele M. , Chaturvedi Pallavi , Xiang Lisha , Suematsu Makoto , Zagzag David , Semenza Gregg L.
Published: April 2023

Supplementary Table S1. Primer sequences used for qPCR.
Data Supplement from Decreased Expression of Cystathionine β-Synthase Promotes Glioma Tumorigenesis
Authors: Takano Naoharu , Sarfraz Yasmeen , Gilkes Daniele M. , Chaturvedi Pallavi , Xiang Lisha , Suematsu Makoto , Zagzag David , Semenza Gregg L.
Published: April 2023

Supplementary Figure S1. Cell proliferation of U87-MG subclones in vitro. 5,000 cells were seeded and cultured under 20% or 1% O2. Viable cell number was counted by trypan blue staining on days 2, 3, and 4, and normalized to the starting cell number (mean + SEM, n = 3). Supplementary Figure S2. Analysis of orthotopic tumors after injection of 1 x 104 cells into the caudate-putamen. (A) Tumor volume was determined by histological analysis 5 weeks after stereotactic injection of U87-MG parental or subclone cells into the brains of SCID mice (bar = mean, n = 7); *p < 0.05 vs shNT. (B) Depth of invasion was determined by histological analysis (mean + SEM, n = 5-7). (C) Anti-CD105 immunohistochemistry was performed and blood vessel density in tumor sections was determined (mean + SEM, n = 10-14). (D) Anti-Ki-67 immunohistochemistry was performed and stained cells were counted (mean + SEM, n = 5-7). (E) Immunohistochemistry was performed to detect active caspase-3 and stained cells were counted (mean + SEM, n = 5-7). Supplementary Figure S3. HIF-2α mRNA levels were determined by RT-qPCR (mean + SEM, n = 3) in parental, shScr, shCBS#07, and shCBS#61 subclones cultured at 20% O2.
Supplementary Figure 9 from Cooperativity of E-cadherin and Smad4 Loss to Promote Diffuse-Type Gastric Adenocarcinoma and Metastasis
Authors: Park Jun Won , Jang Seok Hoon , Park Dong Min , Lim Na Jung , Deng Chuxia , Kim Dae Yong , Green Jeffrey E. , Kim Hark Kyun
Published: April 2023

PDF - 81K, Monolayer growth rate of primary cells after knockdown of beta-catenin.
Supplementary Figure 8 from Cooperativity of E-cadherin and Smad4 Loss to Promote Diffuse-Type Gastric Adenocarcinoma and Metastasis
Authors: Park Jun Won , Jang Seok Hoon , Park Dong Min , Lim Na Jung , Deng Chuxia , Kim Dae Yong , Green Jeffrey E. , Kim Hark Kyun
Published: April 2023

PDF - 97K, EMT features of gastric cancer cell line.
Supplementary Data from Proteasome Subunits Differentially Control Myeloma Cell Viability and Proteasome Inhibitor Sensitivity
Authors: Shi Chang-Xin , Zhu Yuan Xiao , Bruins Laura A. , Bonolo de Campos Cecilia , Stewart William , Braggio Esteban , Stewart A. Keith
Published: April 2023

Ten end stage patients.
Supplemental Figure 6 from EMT Transition Alters Interstitial Fluid Flow–Induced Signaling in ERBB2-Positive Breast Cancer Cells
Authors: Tchafa Alimatou M. , Ta Mi , Reginato Mauricio J. , Shieh Adrian C.
Published: April 2023

Supplemental Figure 6: The number of live and dead cells were counted across 5 separate images per sample; Western blot was performed on total protein harvested from cells grown in 2D.
Supplemental Figure 2 from Notch Signaling Activation Is Associated with Patient Mortality and Increased FGF1-Mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity
Authors: Weaver Alice N. , Burch M. Benjamin , Cooper Tiffiny S. , Della Manna Deborah L. , Wei Shi , Ojesina Akinyemi I. , Rosenthal Eben L. , Yang Eddy S.
Published: April 2023

Clustering and gene set enrichment analyses in TCGA OSCC samples.
Supplemental Figure 1 from Notch Signaling Activation Is Associated with Patient Mortality and Increased FGF1-Mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity
Authors: Weaver Alice N. , Burch M. Benjamin , Cooper Tiffiny S. , Della Manna Deborah L. , Wei Shi , Ojesina Akinyemi I. , Rosenthal Eben L. , Yang Eddy S.
Published: April 2023

Clustering and gene set enrichment analyses in UAB OSCC samples.
Supplementary Table S1 from Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse
Authors: Urrutia Guillermo , Salmonson Ann , Toro-Zapata Jorge , de Assuncao Thiago M. , Mathison Angela , Dusetti Nelson , Iovanna Juan , Urrutia Raul , Lomberk Gwen
Published: April 2023

Supplementary Table 1: List of Antibodies
Supplemental Figure 3 from The YAP-Interacting Phosphatase SHP2 Can Regulate Transcriptional Coactivity and Modulate Sensitivity to Chemotherapy in Cholangiocarcinoma
Authors: Buckarma EeeLN H. , Werneburg Nathan W. , Conboy Caitlin B. , Kabashima Ayano , O'Brien Daniel R. , Wang Chen , Rizvi Sumera , Smoot Rory L.
Published: April 2023

SHP2 mediated deletion following incubation with doxycycline.
FIGURE S4 from c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase–Activated Leukemias
Authors: Muvarak Nidal , Kelley Shannon , Robert Carine , Baer Maria R. , Perrotti Danilo , Gambacorti-Passerini Carlo , Civin Curt , Scheibner Kara , Rassool Feyruz V.
Published: April 2023

FIGURE S4. Western blots for PARP1, LIG3 and c-MYC proteins and MO7e-BCR-ABL1 cells; Flow cytometric data
FIGURE S3 from c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase–Activated Leukemias
Authors: Muvarak Nidal , Kelley Shannon , Robert Carine , Baer Maria R. , Perrotti Danilo , Gambacorti-Passerini Carlo , Civin Curt , Scheibner Kara , Rassool Feyruz V.
Published: April 2023

FIGURE S3. Graphs of correlations between endogenous mRNA expression levels
Supplemental Figure 6 from Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer
Authors: Vickman Renee E. , Crist Scott A. , Kerian Kevin , Eberlin Livia , Cooks R. Graham , Burcham Grant N. , Buhman Kimberly K. , Hu Chang-Deng , Mesecar Andrew D. , Cheng Liang , Ratliff Timothy L.
Published: April 2023

Transcriptional activity of LXRα vs. LXRβ in LNCaP cells.
Supplementary Figure 4 from COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation
Authors: Majumder Mousumi , Landman Erin , Liu Ling , Hess David , Lala Peeyush K.
Published: April 2023

Supplementary Figure 4. Reduced COX-2 Expression after miR-526b knockdown. T
Supplementary Figure S6 from AMPK-Independent LKB1 Activity Is Required for Efficient Epithelial Ovarian Cancer Metastasis
Authors: Buensuceso Adrian , Ramos-Valdes Yudith , DiMattia Gabriel E. , Shepherd Trevor G.
Published: April 2023

Overexpression of DUSP4 in FTE and EOC cells does not alter spheroid formation or viability.
S7 from Augmented TME O-GlcNAcylation Promotes Tumor Proliferation through the Inhibition of p38 MAPK
Authors: Moriwaki Kazumasa , Asahi Michio
Published: April 2023

Supplemental Figure Legends.
OVCAR8 spheroid from AMPK-Independent LKB1 Activity Is Required for Efficient Epithelial Ovarian Cancer Metastasis
Authors: Buensuceso Adrian , Ramos-Valdes Yudith , DiMattia Gabriel E. , Shepherd Trevor G.
Published: April 2023

Single OVCAR8 spheroid formation and growth over time as imaged by IncuCyte ZOOM
S1 from Augmented TME O-GlcNAcylation Promotes Tumor Proliferation through the Inhibition of p38 MAPK
Authors: Moriwaki Kazumasa , Asahi Michio
Published: April 2023

Supplemental Figure 1. O-GlcNAcylation is elevated in various tissues excised from Ogt-Tg/+ mice.
HeyA8-STK11KO spheroid from AMPK-Independent LKB1 Activity Is Required for Efficient Epithelial Ovarian Cancer Metastasis
Authors: Buensuceso Adrian , Ramos-Valdes Yudith , DiMattia Gabriel E. , Shepherd Trevor G.
Published: April 2023

Single HeyA8-STK11KO spheroid formation and growth over time as imaged by IncuCyte ZOOM
Table S1 from Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes
Authors: van der Watt Pauline J. , Roden Laura C. , Davis Kate T. , Parker M. Iqbal , Leaner Virna D.
Published: April 2023

Correlations between gene expression fold changes (R values are shown)
Figure S6 from Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes
Authors: van der Watt Pauline J. , Roden Laura C. , Davis Kate T. , Parker M. Iqbal , Leaner Virna D.
Published: April 2023

WI38 and SVWI38 cell sensitivities to REV-ERBα and RORα agonists, SR9011 and SR1078. A. MTT analysis reveals transformed SVWI38 cells to be more sensitive to REV-ERBα activation, compared to normal WI38 cells. B. WI38 and SVWI38 cells are both sensitive to RORα activation. *p<0.05.
Figure S3 from Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes
Authors: van der Watt Pauline J. , Roden Laura C. , Davis Kate T. , Parker M. Iqbal , Leaner Virna D.
Published: April 2023

Real-time RT-PCR analysis reveals expression of certain circadian clock genes to be unaltered in cancer/transformed cells compared to normal. A. Relative expression of REV-ERBβ and RORβ in transformed SVWI38 compared to normal WI38 fibroblast cells. B. Relative expression of CRY2 (a), PER3 (b), REV-ERBβ (c) and RORβ (d) in cancer cell lines compared to non-cancer ARPE19 cells.