bluuebunny/crossref_metadata_2025 huggingface dataset:
A Theoretical Study of Fe Adsorbed on Pure and Nonmetal (N, F, P, S, Cl)-Doped Ti3C2O2 for Electrocatalytic Nitrogen Reduction
Authors: Luo Heng , Wang Xiaoxu , Wan Chubin , Xie Lu , Song Minhui , Qian Ping
Published: March 2022

The possibility of using transition metal (TM)/MXene as a catalyst for the nitrogen reduction reaction (NRR) was studied by density functional theory, in which TM is an Fe atom, and MXene is pure Ti3C2O2 or Ti3C2O2−x doped with N/F/P/S/Cl. The adsorption energy and Gibbs free energy were calculated to describe the limiting potentials of N2 activation and reduction, respectively. N2 activation was spontaneous, and the reduction potential-limiting step may be the hydrogenation of N2 to *NNH and the desorption of *NH3 to NH3. The charge transfer of the adsorbed Fe atoms to N2 molecules weakened the interaction of N≡N, which indicates that Fe/MXene is a potential catalytic material for the NRR. In particular, doping with nonmetals F and S reduced the limiting potential of the two potential-limiting steps in the reduction reaction, compared with the undoped pure structure. Thus, Fe/MXenes doped with these nonmetals are the best candidates among these structures.
Recent Advancement in Biofluid-Based Glucose Sensors Using Invasive, Minimally Invasive, and Non-Invasive Technologies: A Review
Authors: Reddy Vundrala Sumedha , Agarwal Bhawana , Ye Zhen , Zhang Chuanqi , Roy Kallol , Chinnappan Amutha , Narayan Roger J. , Ramakrishna Seeram , Ghosh Rituparna
Published: March 2022

Biosensors have potentially revolutionized the biomedical field. Their portability, cost-effectiveness, and ease of operation have made the market for these biosensors to grow rapidly. Diabetes mellitus is the condition of having high glucose content in the body, and it has become one of the very common conditions that is leading to deaths worldwide. Although it still has no cure or prevention, if monitored and treated with appropriate medication, the complications can be hindered and mitigated. Glucose content in the body can be detected using various biological fluids, namely blood, sweat, urine, interstitial fluids, tears, breath, and saliva. In the past decade, there has been an influx of potential biosensor technologies for continuous glucose level estimation. This literature review provides a comprehensive update on the recent advances in the field of biofluid-based sensors for glucose level detection in terms of methods, methodology and materials used.
Quantitative Detection of Mastitis Factor IL-6 in Dairy Cow Using the SERS Improved Immunofiltration Assay
Authors: Chen Ruipeng , Wang Hui , Zhao Yiguang , Nan Xuemei , Wei Wensong , Du Chunmei , Zhang Fan , Luo Qingyao , Yang Liang , Xiong Benhai
Published: March 2022

Interleukin-6 (IL-6) is generally used as a biomarker for the evaluation of inflammatory infection in humans and animals. However, there is no approach for the on-site and rapid detection of IL-6 for the monitoring of mastitis in dairy farm scenarios. A rapid and highly sensitive surface enhanced Raman scattering (SERS) immunofiltration assay (IFA) for IL-6 detection was developed in the present study. In this assay, a high sensitivity gold core silver shell SERS nanotag with Raman molecule 4-mercaptobenzoic acid (4-MBA) embedded into the gap was fabricated for labelling. Through the immuno-specific combination of the antigen and antibody, antibody conjugated SERS nanotags were captured on the test zone, which facilitated the SERS measurement. The quantitation of IL-6 was performed by the readout Raman signal in the test region. The results showed that the detection limit (LOD) of IL-6 in milk was 0.35 pg mL−1, which was far below the threshold value of 254.32 pg mL−1. The recovery of the spiking experiment was 87.0–102.7%, with coefficients of variation below 9.0% demonstrating high assay accuracy and precision. We believe the immunosensor developed in the current study could be a promising tool for the rapid assessment of mastitis by detecting milk IL-6 in dairy cows. Moreover, this versatile immunosensor could also be applied for the detection of a wide range of analytes in dairy cow healthy monitoring.
Synchronous Defect and Interface Engineering of NiMoO4 Nanowire Arrays for High-Performance Supercapacitors
Authors: Wang Pengcheng , Ding Xinying , Zhe Rongjie , Zhu Ting , Qing Chen , Liu Yingkai , Wang Hong-En
Published: March 2022

Developing high-performance electrode materials is in high demand for the development of supercapacitors. Herein, defect and interface engineering has been simultaneously realized in NiMoO4 nanowire arrays (NWAs) using a simple sucrose coating followed by an annealing process. The resultant hierarchical oxygen-deficient NiMoO4@C NWAs (denoted as “NiMoO4−x@C”) are grown directly on conductive ferronickel foam substrates. This composite affords direct electrical contact with the substrates and directional electron transport, as well as short ionic diffusion pathways. Furthermore, the coating of the amorphous carbon shell and the introduction of oxygen vacancies effectively enhance the electrical conductivity of NiMoO4. In addition, the coated carbon layer improves the structural stability of the NiMoO4 in the whole charging and discharging process, significantly enhancing the cycling stability of the electrode. Consequently, the NiMoO4−x@C electrode delivers a high areal capacitance of 2.24 F cm−2 (1720 F g−1) at a current density of 1 mA cm−2 and superior cycling stability of 84.5% retention after 6000 cycles at 20 mA cm−2. Furthermore, an asymmetric super-capacitor device (ASC) has been constructed with NiMoO4−x@C as the positive electrode and activated carbon (AC) as the negative electrode. The as-assembled ASC device shows excellent electrochemical performance with a high energy density of 51.6 W h kg−1 at a power density of 203.95 W kg−1. Moreover, the NiMoO4//AC ASC device manifests remarkable cyclability with 84.5% of capacitance retention over 6000 cycles. The results demonstrate that the NiMoO4−x@C composite is a promising material for electrochemical energy storage. This work can give new insights on the design and development of novel functional electrode materials via defect and interface engineering through simple yet effective chemical routes.
The Effect of Ag-Decoration on rGO/Water Nanofluid Thermal Conductivity and Viscosity
Authors: Lozano-Steinmetz Felipe , Martínez Victor A. , Vasco Diego A. , Sepúlveda-Mualin Alonso , Singh Dinesh Patrap
Published: March 2022

Carbon-based nanomaterials have a high thermal conductivity, which can be exploited to prepare nanofluids. Graphene is a hydrophobic substance, and consequently, graphene-based nanofluid stability is improved by adding surfactants. An attractive alternative is the decoration of reduced graphene oxide (rGO) with metallic materials to improve the thermal conductivity without affecting the stability of nanofluids. This study focuses on the synthesis and characterization of rGO/Ag (0.1 wt.%) aqueous nanofluids. Moreover, the effects of the Ag concentration (0.01–1 M) on the thermal conductivity and viscosity during the synthesis of rGO/Ag composite are analyzed. The nanofluid thermal conductivity showed increases in relation to the base fluid, the most promising being 28.43 and 26.25% for 0.1 and 1 M of Ag, respectively. Furthermore, the nanofluids were Newtonian in the analyzed range of shear rates and presented a moderate increase (<11%) in viscosity. Aqueous nanofluids based on rGO/Ag nanocomposites are a potential alternative for applications as heat transfer fluids.
Asymmetric Electrokinetic Energy Conversion in Slip Conical Nanopores
Authors: Chang Chih-Chang
Published: March 2022

Ion current rectification (ICR) phenomena in asymmetric nanofluidic structures, such as conical-shaped nanopores and funnel-shaped nanochannels, have been widely investigated in recent decades. To date, the effect of asymmetric nanofluidic structures on electrokinetic power generation driven by the streaming current/potential has not been explored. Accordingly, this study employed a numerical model based on the Poisson equation, Nernst–Planck equation, and Navier–Stokes equation to investigate the electrokinetic energy conversion (EKEC) in a conical nanopore while considering hydrodynamic slippage. The results indicated that the asymmetric characteristics of streaming current (short-circuit current), streaming potential (open-circuit voltage), maximum power generation, maximum conversion efficiency, and flow rate were observed in conical nanopores under the forward pressure bias (tip-to-base direction) and reverse pressure bias (base-to-tip direction) once the nonequilibrium ion concentration polarization (ICP) became considerable. The rectification behaviors in the streaming current, maximum power, and maximum conversion efficiency were all shown to be opposite to those of the well-known ICR in conical nanopores. In other words, the reverse pressure bias revealed a higher EKEC performance than the forward pressure bias. It was concluded that the asymmetric behavior in EKEC is attributed to the asymmetric electrical resistance resulting from asymmetric ion depletion and ion enrichment. Particularly, it was found that the decrease in electrical resistance (i.e., the change in electrical resistance dominated by the ion enrichment) observed in the reverse pressure bias enhanced the maximum power and maximum conversion efficiency. The asymmetric EKEC characteristics became more significant with increasing slip length, surface charge density, cone angle, and pressure bias, especially at lower salt concentrations. The present findings provide useful information for the future development of EKEC in engineered membranes with asymmetric nanopores.
Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis
Authors: Sargazi Saman , Laraib Ushna , Er Simge , Rahdar Abbas , Hassanisaadi Mohadeseh , Zafar Muhammad Nadeem , Díez-Pascual Ana M. , Bilal Muhammad
Published: March 2022

Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance in imaging techniques. The wide availability of biological precursors used in plant-based synthesized AuNPs allows for the development of large-scale production in a greener manner. Conventional cancer therapies, such as surgery and chemotherapy, have significant limitations and frequently fail to produce satisfying results. AuNPs have a prolonged circulation time, allow easy modification with ligands detected via cancer cell surface receptors, and increase uptake through receptor-mediated endocytosis. To exploit these unique features, studies have been carried out on the use of AuNPs as contrast agents for X-ray-based imaging techniques (i.e., computed tomography). As nanocarriers, AuNPs synthesized by nontoxic and biocompatible plants to deliver therapeutic biomolecules could be a significant stride forward in the effective treatment of various cancers. Fluorescent-plant-based markers, including AuNPs, fabricated using Medicago sativa, Olax Scandens, H. ambavilla, and H. lanceolatum, have been used in detecting cancers. Moreover, green synthesized AuNPs using various extracts have been applied for the treatment of different types of solid tumors. However, the cytotoxicity of AuNPs primarily depends on their size, surface reactivity, and surface area. In this review, the benefits of plant-based materials in cancer therapy are firstly explained. Then, considering the valuable position of AuNPs in medicine, the application of AuNPs in cancer therapy and detection is highlighted with an emphasis on limitations faced by the application of such NPs in drug delivery platforms.
Date-Palm-Derived Cellulose Nanocrystals as Reinforcing Agents for Poly(vinyl alcohol)/Guar-Gum-Based Phase-Separated Composite Films
Authors: Shaikh Hamid M. , Anis Arfat , Poulose Anesh Manjaly , Madhar Niyaz Ahamad , Al-Zahrani Saeed M.
Published: March 2022

The current study delineates the use of date-palm-derived cellulose nanocrystals (dp-CNCs) as reinforcing agents. dp-CNCs were incorporated in varying amounts to poly(vinyl alcohol)/guar-gum-based phase-separated composite films. The films were prepared by using the solution casting method, which employed glutaraldehyde as the crosslinking agent. Subsequently, the films were characterized by bright field and polarizing microscopy, UV-Vis spectroscopy, FTIR spectroscopy, and mechanical study. The microscopic techniques suggested that phase-separated films were formed, whose microstructure could be tailored by incorporating dp-CNCs. At higher levels of dp-CNC content, microcracks could be observed in the films. The transparency of the phase-separated films was not significantly altered when the dp-CNC content was on the lower side. FTIR spectroscopy suggested the presence of hydrogen bonding within the phase-separated films. dp-CNCs showed reinforcing effects at the lowest amount, whereas the mechanical properties of the films were compromised at higher dp-CNC content. Moxifloxacin was included in the films to determine the capability of the films as a drug delivery vehicle. It was found that the release of the drug could be tailored by altering the dp-CNC content within the phase-separated films. In gist, the developed dp-CNC-loaded poly(vinyl alcohol)/guar-gum-based phase-separated composite films could be explored as a drug delivery vehicle.
RETRACTED: Associations Between Christian Orthodox Church Fasting and Adherence to the World Cancer Research Fund’s Cancer Prevention Recommendations
Authors: Kokkinopoulou Anna , McGowan Rachel , Brogan Yvonne , Armstrong Julie , Pagkalos Ioannis , Hassapidou Maria , Kafatos Anthony
Published: March 2022

Objective: Studies regarding the health effects of religious fasting have increased in the last decade. The aim of this research was to investigate the relationship between Christian Orthodox Church (COC) fasting recommendations and cancer risk, with a specific focus on fibre, fruit, vegetables, and red and processed meat consumption. Methods: In this cross-sectional study, participants included 361 individuals from Northern Greece. One hundred and seventy-six participants followed the COC fasting regime for more than 10 years, and 185 participants did not follow any restrictive dietary patterns. Diet was assessed using a 114-item food frequency questionnaire. Results: Fasters had a more favourable dietary intake compared to non-fasters, with fasters having a higher consumption of fruit and vegetables (p = 0.009) and a significantly lower consumption of total processed meat (p < 0.001) compared to non-fasters. No significant differences were observed in the consumption of fibre and red meat consumption between the two groups. Conclusions: Following the World Cancer Research Fund Cancer Recommendations, fasters are at a potentially lowering risk of developing colorectal cancer than non-fasters due to their more favourable dietary intake. Furthermore, higher consumption of fruit and vegetables with a lower consumption of total processed meat contributes to lower the risk of metabolic syndrome. Public health strategies based on following the structured COC fasting recommendations might hopefully contribute to the prevention of metabolic syndrome and colorectal cancer.
Health-Nutrients and Origin Awareness: Implications for Regional Wine Market-Segmentation Strategies Using a Latent Analysis
Authors: Petrontino Alessandro , Frem Michel , Fucilli Vincenzo , Tricarico Giovanni , Bozzo Francesco
Published: March 2022

A healthy-nutrient wine has been recently developed by Apulian wineries (southern Italy), using autochthonous wine grapes cultivars, selected strains and specific processes of production. As such, this research elicits Italian wine consumers’ preferences towards this innovative Apulian wine with regard to additional labelling information associated with health-nutrients and the origin of grapes on the bottle of wine. For this purpose, a social survey based on the choice experiment approach is considered. The results reveal a heterogeneity of preferences among respondents for which the origin of wine grapes cultivars is the most appreciated (an average Willingness-to-Pay of EUR 6.57), thereby inducing an increase in their function utility, while the health-nutrients attribute is relatively less appreciated (an average Willingness-to-Pay of EUR 3.95). Furthermore, four class consumers’ cluster profile have been identified in respect to their: (i) behavior and propensity to wine consumption and purchase, (ii) health-claims importance on the wine bottle label, (iii) socio-economic characteristics and (iv) health conditions. This paper has marketing and public implications and contributes to an understanding of how additional information on the label of a wine bottle may affect the market-segmentation, influence wine consumers’ utility, protect their health and increase their level of awareness to wine ingredients labelling.
Hurricane-Induced Oceanic Carbon Changes in the Upper Ocean
Authors: McGee Laura , He Ruoying
Published: March 2022

Changes in marine carbon cycling due to hurricanes with different intensity and translation speeds have not been systematically investigated. This study uses an idealized coupled physical-biogeochemical model and a suite of model sensitivity analyses to better quantify the relationship between hurricane characteristics and marine property changes, including variations in air-sea carbon flux and partial pressure of carbon dioxide in water (pCO2w). We find that strong (category 4–5), mid-speed (5–8 m/s) storms cause the most carbon flux from the atmosphere to the ocean, and that the relationship between air-sea carbon flux and hurricane properties is non-linear. Climate models that do not consider synoptic-scale, storm-induced physical-biogeochemical coupling may underestimate regional carbon sinks.
Dehydrocrenatidine Induces Liver Cancer Cell Apoptosis by Suppressing JNK-Mediated Signaling
Authors: Velmurugan Bharath Kumar , Hsieh Ming-Ju , Lin Chia-Chieh , Ho Hsin-Yu , Hsieh Ming-Chang
Published: March 2022

Liver cancer is a leading cause of death worldwide. Despite advancement in therapeutic interventions, liver cancer is associated with poor prognosis because of highly lethal characteristics and high recurrence rate. In the present study, the anticancer potential of a plant-based alkaloid namely dehydrocrenatidine has been evaluated in human liver cancer cells. The study findings revealed that dehydrocrenatidine reduced cancer cell viability by arresting cell cycle at G2/M phase and activating mitochondria-mediated and death receptor-mediated apoptotic pathways. Specifically, dehydrocrenatidine significantly increased the expression of extrinsic pathway components (FAS, DR5, FADD, and TRADD) as well as intrinsic pathway components (Bax and Bim L/S) in liver cancer cells. In addition, dehydrocrenatidine significantly increased the cleavage and activation of PARP and caspases 3, 8, and 9. The analysis of upstream signaling pathways revealed that dehydrocrenatidine induced caspase-mediated apoptosis by suppressing the phosphorylation of JNK1/2. Taken together, the study identifies dehydrocrenatidine as a potent anticancer agent that can be use clinically to inhibit the proliferation of human liver cancer cells.
Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from Rhodospirillum rubrum by Conjugation with Chitosan-Based Cationic Polyelectrolytes
Authors: Dobryakova Natalia V. , Zhdanov Dmitry D. , Sokolov Nikolay N. , Aleksandrova Svetlana S. , Pokrovskaya Marina V. , Kudryashova Elena V.
Published: March 2022

L-asparaginases (L-ASNases, EC 3.5.1.1) are a family of enzymes that are widely used for the treatment of lymphoblastic leukemias. L-ASNase from Rhodospirillum rubrum (RrA) has a low molecular weight, low glutaminase activity, and low immunogenicity, making it a promising enzyme for antitumor drug development. In our work, the complex formation and covalent conjugation of the enzyme with synthetic or natural polycationic polymers was studied. Among non-covalent polyelectrolyte complexes (PEC), polyethyleneimine (PEI) yielded the highest effect on RrA, increasing its activity by 30%. The RrA-PEI complex had increased stability to trypsinolysis, with an inactivation constant decrease up to 10-fold compared to that of the native enzyme. The covalent conjugation of RrA with chitosan-PEI, chitosan-polyethylene glycol (chitosan-PEG), and chitosan-glycol resulted in an increase in the specific activity of L-asparagine (up to 30%). RrA-chitosan-PEG demonstrated dramatically (by 60%) increased cytotoxic activity for human chronic myeloma leukemia K562 cells in comparison to the native enzyme. The antiproliferative activity of RrA and its conjugates was significantly higher (up to 50%) than for that of the commercially available EcA at the same concentration. The results of this study demonstrated that RrA conjugates with polycations can become a promising strategy for antitumor drug development.
Analytical Quality by Design (AQbD) Approach to the Development of In Vitro Release Test for Topical Hydrogel
Authors: Szoleczky Réka , Budai-Szűcs Mária , Csányi Erzsébet , Berkó Szilvia , Tonka-Nagy Péter , Csóka Ildikó , Kovács Anita
Published: March 2022

The aim of our study was to adapt the analytical quality by design (AQbD) approach to design an effective in vitro release test method using USP apparatus IV with a semi-solid adapter (SSA) for diclofenac sodium hydrogel. The analytical target profile (ATP) of the in vitro release test and ultra-high-performance liquid chromatography were defined; the critical method attributes (CMAs) (min. 70% of the drug should be released during the test, six time points should be obtained in the linear portion of the drug release profile, and the relative standard deviation of the released drug should not be over 10%) were selected. An initial risk assessment was carried out, in which the CMAs (ionic strength, the pH of the media, membrane type, the rate of flow, the volume of the SSA (sample amount), the individual flow rate of cells, drug concentration %, and the composition of the product) were identified. With the results, it was possible to determine the high-risk parameters of the in vitro drug release studies performed with the USP apparatus IV with SSA, which were the pH of the medium and the sample weight of the product. Focusing on these parameters, we developed a test protocol for our hydrogel system.
Nanoparticles Targeting the Molecular Pathways of Heart Remodeling and Regeneration
Authors: Gonciar Diana , Mocan Teodora , Agoston-Coldea Lucia
Published: March 2022

Cardiovascular diseases are the main cause of death worldwide, a trend that will continue to grow over the next decade. The heart consists of a complex cellular network based mainly on cardiomyocytes, but also on endothelial cells, smooth muscle cells, fibroblasts, and pericytes, which closely communicate through paracrine factors and direct contact. These interactions serve as valuable targets in understanding the phenomenon of heart remodeling and regeneration. The advances in nanomedicine in the controlled delivery of active pharmacological agents are remarkable and may provide substantial contribution to the treatment of heart diseases. This review aims to summarize the main mechanisms involved in cardiac remodeling and regeneration and how they have been applied in nanomedicine.
An Overview of siRNA Delivery Strategies for Urological Cancers
Authors: Halib Nadia , Pavan Nicola , Trombetta Carlo , Dapas Barbara , Farra Rossella , Scaggiante Bruna , Grassi Mario , Grassi Gabriele
Published: March 2022

The treatment of urological cancers has been significantly improved in recent years. However, for the advanced stages of these cancers and/or for those developing resistance, novel therapeutic options need to be developed. Among the innovative strategies, the use of small interfering RNA (siRNA) seems to be of great therapeutic interest. siRNAs are double-stranded RNA molecules which can specifically target virtually any mRNA of pathological genes. For this reason, siRNAs have a great therapeutic potential for human diseases including urological cancers. However, the fragile nature of siRNAs in the biological environment imposes the development of appropriate delivery systems to protect them. Thus, ensuring siRNA reaches its deep tissue target while maintaining structural and functional integrity represents one of the major challenges. To reach this goal, siRNA-based therapies require the development of fine, tailor-made delivery systems. Polymeric nanoparticles, lipid nanoparticles, nanobubbles and magnetic nanoparticles are among nano-delivery systems studied recently to meet this demand. In this review, after an introduction about the main features of urological tumors, we describe siRNA characteristics together with representative delivery systems developed for urology applications; the examples reported are subdivided on the basis of the different delivery materials and on the different urological cancers.
Power Output of Two Semiconductor Lasers: An Observational Study
Authors: Xue Vicky Wenqing , Yin Iris Xiaoxue , Niu John Yun , Luk Kenneth , Lo Edward Chin Man , Chu Chun Hung
Published: March 2022

The objective of this study was to evaluate the power output of two dental devices. The study examined two semiconductor lasers, namely, SIROLaser Blue (445 nm, 970 nm) and Picasso (810 nm). The power output performance was studied at the maximum output power of the devices. The study compared the preset power output measured by a power meter in a continuous-wave mode and in pulsed mode at 50% duty cycles. Ten 60 s measurements were performed for each setting. The largest difference between the stipulated and the actual output power at continuous-wave (D-cw) and pulsed (D-p) modes was calculated. Moreover, the percentage variations in the mean output power at continuous-wave (%D-cw) and pulsed (%D-p) modes were calculated. The D-cw values for 445 nm, 970 nm, and 810 nm lasers were 0.7 W, 0.5 W, and −0.3 W, respectively, and %D-cw values were 21%, 23%, and −8%, respectively. The D-p values for 445 nm, 970 nm, and 810 nm lasers were 1.1 W, 0.5 W, and −0.1 W, respectively, whereas the %D-p values were 37%, 26%, and −3%, respectively. This study found that the actual power is not necessarily lower but can be higher than the displayed power output. Clinicians are recommended to calibrate the laser output by using a power meter before use.
Natural Melanin: Current Trends, and Future Approaches, with Especial Reference to Microbial Source
Authors: El-Naggar Noura El-Ahmady , Saber WesamEldin I. A.
Published: March 2022

Melanin is a universal natural dark polymeric pigment, arising in microorganisms, animals, and plants. There is a couple of pieces of literature on melanin, each focusing on a different issue, the goal of the present review is to focus on microbial melanin. It has numerous benefits with very few drawbacks. The current situation and expected trends are discussed. Intriguing, numerous studies have provoked a serious necessity for a comprehensive assessment of microbial melanin pigments. So that, such review would help scholars from diverse backgrounds to realize the importance of melanin pigments isolated from microorganisms, with this aim in mind, information, and hypothesis from this review could be the paradigm for studies on melanin in the next era.
Design and Analysis of CFRP Drilling by Electrical Discharge Machining
Authors: Roldan-Jimenez Luis , Bañon Fermin , Valerga Ana P. , Fernandez-Vidal Severo R.
Published: March 2022

The novelty of EDM machining as a drilling operation for composite materials means that there is no consensus on the influence of the parameters that optimise the final quality. For these reasons, a characterisation of the EDM drilling process of a unidirectional composite material has been developed. The influence of several cutting parameters has been related to the quality of the final hole obtained. Thus, macrogeometric aspects in terms of conicity and final diameter and microgeometric aspects in terms of surface quality have been evaluated. In addition, the final state of the material and the wear of the electrode have been evaluated by visual inspection, allowing the range of cutting parameters that offer the best performance to be established. Finally, a series of contour diagrams based on predictive models have been obtained to establish a direct relationship between input and output variables.
Physicochemical, Mechanical, and Structural Properties of Bio-Active Films Based on Biological-Chemical Chitosan, a Novel Ramon (Brosimum alicastrum) Starch, and Quercetin
Authors: Pech-Cohuo Soledad Cecilia , Martín-López Héctor , Uribe-Calderón Jorge , González-Canché Nancy Guadalupe , Salgado-Tránsito Iván , May-Pat Alejandro , Cuevas-Bernardino Juan Carlos , Ayora-Talavera Teresa , Cervantes-Uc José Manuel , Pacheco Neith
Published: March 2022

The properties of biological-chemical chitosan (BCh) films from marine-industrial waste and a non-conventional Ramon starch (RS) (Brosimum alicastrum) were investigated. Blended films of BCh/RS were prepared to a volume ratio of 4:1 and 1:4, named (BChRS-80+q, biological-chemical chitosan 80% v/v and Ramon starch, BChRS-20+q, biological-chemical chitosan 20% v/v and Ramon starch, both with quercetin), Films from commercial chitosan (CCh) and corn starch (CS), alone or blended (CChCS-80+q, commercial chitosan 80% v/v and corn starch, CChCS-20+q commercial chitosan 20% v/v and corn starch, both with quercetin) were also prepared for comparison purposes. Films were investigated for their physicochemical characteristics such as thickness, moisture, swelling, water-vapor permeability, and water solubility. In addition, their mechanical and structural properties were studied using Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric analysis (TGA) and Scanning Electron Microscopy (SEM) techniques. Antioxidant activity was evaluated as radical scavenging, and antimicrobial effect was also determined. The BCh and RS films presented similar tensile strength values compared with commercial biopolymers. Only films with chitosan presented antioxidant and antimicrobial activity. The FTIR spectra confirmed the interactions between functional groups of the biopolymers. Although, BChRS-80+q and BChRS-20+q films exhibited poor mechanical performance compared to their commercial counterparts, they showed good thermal stability, and improved antioxidant and antimicrobial activity in the presence of quercetin. BChRS-80+q and BChRS-20+q films have promising applications due to their biological activity and mechanical properties, based on a novel material that has been underutilized (Ramon starch) that does not compete with materials for human feeding and may be used as a coating for food products.
Effectiveness and Efficiency of Externally Bonded CFRP Sheets for Shear Strengthening of RC Beam-Column Joints
Authors: Wang Bu , Wu Xianhui , Liu Qi , Wu Yueyue , Huang Fei , Xu Linfeng , Wu Xing , Deng Yuanxin
Published: March 2022

To develop feasible carbon fiber reinforced polymer (CFRP) retrofit schemes for the shear strengthening of real three-dimensional reinforced concrete (RC) beam-column joints, a series of parameters in relation to the contributions of the CFRP sheets externally bonded to joint panels was numerically investigated in this study. The parameters include CFRP reinforcement ratio, CFRP layout, transverse beam-to-joint panel width ratio, transverse beam-to-joint panel height ratio, location of transverse beam, and number of transverse beams. Strengthening efficiency, a new dimensionless index, was introduced to evaluate the residual effect of a CFRP-strengthening system weakened by the presence of transverse beams in comparison with the increase in joint shear capacity in relation to the one-way counterpart. The results obtained from 44 nonlinear finite element models, which were calibrated against experimental observations, confirmed the effectiveness of the CFRP strengthening technique with regard to the relatively wide ranges of the parameters. The significant differences among the roles of the parameters were revealed, and the reasons behind the differences were analyzed. Furthermore, the shear mechanism of the CFRP-retrofitted joint panels was discussed with the proposed strut-and-tie model.
Methodologies to Assess the Biodegradability of Bio-Based Polymers—Current Knowledge and Existing Gaps
Authors: Pires João Ricardo Afonso , Souza Victor Gomes Lauriano , Fuciños Pablo , Pastrana Lorenzo , Fernando Ana Luísa
Published: March 2022

Our society lives in a time of transition where traditional petroleum-based polymers/plastics are being replaced by more sustainable alternative materials. To consider these bioproducts as more viable options than the actual ones, it is demanded to ensure that they are fully biodegradable or compostable and that there is no release of hazardous compounds to the environment with their degradation. It is then essential to adapt the legislation to support novel specific guidelines to test the biodegradability of each biopolymer in varied environments, and consequently, establish consistent data to design a coherent labeling system. This review work aims to point out the current standards that can serve as a basis for the characterization of biopolymers’ biodegradation profile in different environments (soil, compost, and aquatic systems) and identify other laboratory methodologies that have been adopted for the same purpose. With the information gathered in this work, it was possible to identify remaining gaps in existing national and international standards to help establish new validation criteria to be introduced in future research and policies related to bioplastics to boost the sustainable progress of this rising industry.
Mitigation of Routing Congestion on Data Networks: A Quantum Game Theory Approach
Authors: Silva Agustin , Zabaleta Omar G. , Arizmendi Constancio M.
Published: March 2022

Because of the sustained growth of information and mobile users transmitting a great amount of data packets, modern network performances are being seriously affected by congestion problems. In fact, congestion management is a challenging task that can be roughly summarized as a trade off between transmission latency and cost. In order to contribute to solve the congestion problem on communication networks, a novel framework based on a quantum game model is proposed, where network packets compete selfishly for their fastest route. Simulations show that final network routing and traveling times achieved with the quantum version outperform those obtained with a classical game model with the same options for packet transmission for both. Pareto optimality and Nash equilibrium are studied as well as the influence of simulated and real noise in the quantum protocol. This leads to the opportunity of developing full-stack protocols that may be capable of taking advantage of the quantum properties for optimizing communication systems. Due to its generality, this game approach can be applied both in classical complex networks and in future quantum networks in order to maximize the performance of the quantum internet.
Brazilian Adaptation and Validation of the Religious and Spiritual Struggles (RSS) Scale—Extended and Short Version
Authors: Esperandio Mary Rute Gomes , Viacava Juan José Camou , Franco Renato Soleiman , Pargament Kenneth I. , Exline Julie J.
Published: March 2022

Studies highlight that although the spiritual/religious dimension is commonly used as a resource for coping with stress and suffering, sometimes this dimension can also be a locus of struggles. The Religious and Spiritual Struggles (RSS) Scale, composed of 26 items (extended version), is an instrument that assesses the presence of six types of spiritual struggles, categorized into three major categories: Intrapersonal, Interpersonal, and Supernatural. More recently, studies have presented a leaner version, with 14 items (short version), also suitable for evaluating religious/spiritual struggles. This study aimed to validate the RSS Scale, in its two versions, in the Brazilian cultural context and was able to attest to its quality and reliability, albeit with small variations. The Brazilian extended version presented six components (similar to the original version) explaining 68.48% of variance and 0.907 of KMO. Two items were withdrawn due to low loadings, but the psychometric qualities of both versions in two different samples (one wide sample and one with LGBTQIA+ individuals) were maintained. The reliability (Cronbach’s alpha) for each one of the six components ranged from 0.78 to 0.88 (24 items) and from 0.73 to 0.83 (14 items). The TLI and CFI were, respectively, 0.934 and 0.945 (24 items) and 0.982 and 0.988 for the short version (14 items). Furthermore, convergent validity tests indicated correlations with the Satisfaction with Life Scale. The RSS Scale (the Brazilian versions with 24 and 14 items), demonstrated reliability in the studied sample and can be applied in clinical and research contexts.
Advancements of Geodetic Activities in Nepal: A Review on Pre- and Post-2015 Gorkha Earthquake Eras with Future Directions
Authors: KC Shanker , Acharya Tri Dev
Published: March 2022

From celestial objects to every feature on Earth, geodesy provides a reference frame and is the foundation for surveying, mapping, and other geoscience activities. In Nepal, geodesy was officially introduced after 1924 to prepare the topographic map series. Although the previous geodetic project occurred with foreign assistance, Nepal is using national resources to conduct milestone projects such as the re-measurement of Mount Everest height in 2020 and the ongoing LiDAR survey of western Terai. Taking the 2015 Gorkha earthquake as a reference, this paper reviews the past and present geodetic activities in Nepal. It presents the history of conventional Nepal datum as a horizontal datum and Indian mean sea level-based vertical datum, and modern satellite geodesy works on the Himalayas. Considering recent earthquakes, continuous crustal motion, international and global compliance, and increasing demand for precise positional accuracy from the users and stakeholders, this paper discusses future directions to build, establish, maintain, and operate modern terrestrial, height, and gravity reference systems and frames. This paper consolidates many reports and experiences from Nepal and will serve as useful documentation for newcomers whose interests align in geodesy and Nepal.
Aloft Transport of Haze Aerosols to Xuzhou, Eastern China: Optical Properties, Sources, Type, and Components
Authors: Qin Kai , He Qin , Zhang Yishu , Cohen Jason Blake , Tiwari Pravash , Lolli Simone
Published: March 2022

Rapid industrialization and urbanization have caused frequent haze pollution episodes during winter in eastern China. Considering that the vertical profile of the aerosol properties changes significantly with altitude, investigating aerosol aloft information via satellite remote sensing is essential for studying regional transport, climate radiative effects, and air quality. Through a synergic approach between lidar, the AErosol RObotic NETwork sunphotometer observations, and WRF-Chem simulations, several transboundary aloft transport events of haze aerosols to Xuzhou, eastern China, are investigated in terms of source, type, and composition and the impact on optical properties. Upper-air aerosol layers are short-lived tiny particles that increase the total aerosol optical depth (AOD). The aloft aerosols not only play a critical role during the haze event, enhancing the scattering of aerosol particles significantly but also cause a rise in the AOD and the Ångström exponent (AE), which increases the proportion of fine particles, exacerbating the pollution level near the surface. Based on the model simulation results, our study highlights that the transported aloft aerosols lead to the rapid formation of secondary inorganic substances, such as secondary sulfates, nitrates, and ammonium salts, which strongly contribute to haze event formation. Moreover, the results provide evidence that the haze frequency events associated with polluted dust outbreaks were higher for 2014–2015 winter. A closer analysis shows that the advected dust layers over Xuzhou originated from Inner Mongolia and the Xinjiang Uygur Autonomous Region. The study of the occurrence frequency, height, thickness, and optical properties of aloft anthropogenic haze in China will further deepen our understanding and provide a strong basis to assess aerosol impact on transport and the Earth–atmosphere radiative balance.
Fast Radiative Transfer Approximating Ice Hydrometeor Orientation and Its Implication on IWP Retrievals
Authors: Kaur Inderpreet , Eriksson Patrick , Barlakas Vasileios , Pfreundschuh Simon , Fox Stuart
Published: March 2022

The accurate simulation of microwave observations of clouds and precipitation are computationally challenging. A common simplification is the assumption of totally random orientation (TRO); however, studies have revealed that TRO occurs relatively infrequently in reality. A more appropriate assumption is that of azimuthally random orientation (ARO), but so far it has been a computationally expensive task. Recently a fast approximate approach was introduced that incorporates hydrometeor orientation into the assimilation of data from microwave conically scanning instruments. The approach scales the extinction in vertical (V) and horizontal (H) polarised channels to approximate ARO. In this study, the application of the approach was extended to a more basic radiative transfer perspective using the Atmospheric Radiative Transfer Simulator and the high-frequency channels of the Global Precipitation Measurement Microwave Imager (GMI). The comparison of forward simulations and GMI observations showed that with a random selection of scaling factors from a uniform distribution between 1 and 1.4–1.5, it is possible to mimic the full distribution of observed polarisation differences at 166 GHz over land and water. The applicability of this model at 660 GHz was also successfully demonstrated by means of existing airborne data. As a complement, a statistical model for polarised snow emissivity between 160 and 190 GHz was also developed. Combining the two models made it possible to reproduce the polarisation signals that were observed over all surface types, including snow and sea ice. Further, we also investigated the impact of orientation on the ice water path (IWP) retrievals. It has been shown that ignoring hydrometeor orientation has a significant negative impact (∼20% in the tropics) on retrieval accuracy. The retrieval with GMI observations produced highly realistic IWP distributions. A significant highlight was the retrieval over snow covered regions, which have been neglected in previous retrieval studies. These results provide increased confidence in the performance of passive microwave observation simulations and mark an essential step towards developing the retrievals of ice hydrometeor properties based on data from GMI, the Ice Cloud Imager (ICI) and other conically scanning instruments.
Analysis of Land Use Change and Driving Mechanisms in Vietnam during the Period 2000–2020
Authors: Guo Xuan , Ye Junzhi , Hu Yunfeng
Published: March 2022

High-accuracy, long-time-series and large-scale land classification mapping are essential for assessing the evolutionary patterns of land systems and developing sustainability studies. In this paper, using Google Earth Engine (GEE) and Landsat satellite remote sensing images, based on the Random Forest (RF) algorithm, we carried out remote sensing classification to obtain a year-by-year land use/cover data set in Vietnam over the past 21 years (2000–2020). Further applying principal component analysis and multiple linear regression methods, we examined the spatio-temporal characteristics, dynamic changes and driving mechanisms of land use change. The results show the following: (1) The RF classification algorithm supported by the GEE can quickly and accurately obtain a land use/cover data set. The overall classification accuracy is 0.91 ± 0.01. (2) The land cover types in Vietnam are dominated by woodland and cropland, with an area share of 54.62% and 37.90%, respectively. In the past 20 years, the area of built-up land has increased the most (+93.49%), followed by the area of water bodies (+54.19%), while the area of woodland has remained almost unchanged. (3) The expansion of built-up land is driven by regional economic development; the area changes in cropland, water bodies and woodland are influenced by both national economic development and climate change. The results of the study provide a basis for assessing land use policies in Vietnam and a reference methodological framework for rapid land mapping and analysis in other countries in the China–Indochina Peninsula.
Inertial Motion Capture-Based Wearable Systems for Estimation of Joint Kinetics: A Systematic Review
Authors: Lee Chang June , Lee Jung Keun
Published: March 2022

In biomechanics, joint kinetics has an important role in evaluating the mechanical load of the joint and understanding its motor function. Although an optical motion capture (OMC) system has mainly been used to evaluate joint kinetics in combination with force plates, inertial motion capture (IMC) systems have recently been emerging in joint kinetic analysis due to their wearability and ubiquitous measurement capability. In this regard, numerous studies have been conducted to estimate joint kinetics using IMC-based wearable systems. However, these have not been comprehensively addressed yet. Thus, the aim of this review is to explore the methodology of the current studies on estimating joint kinetic variables by means of an IMC system. From a systematic search of the literature, 48 studies were selected. This paper summarizes the content of the selected literature in terms of the (i) study characteristics, (ii) methodologies, and (iii) study results. The estimation methods of the selected studies are categorized into two types: the inverse dynamics-based method and the machine learning-based method. While these two methods presented different characteristics in estimating the kinetic variables, it was demonstrated in the literature that both methods could be applied with good performance for the kinetic analysis of joints in different daily activities.
A High-Precision Method for Segmentation and Recognition of Shopping Mall Plans
Authors: Su Ming , Shi Wei , Zhao Dangjun , Cheng Dongyang , Zhang Junchao
Published: March 2022

Most studies on map segmentation and recognition are focused on architectural floor plans, while there are very few analyses of shopping mall plans. The objective of the work is to accurately segment and recognize the shopping mall plan, obtaining location and semantic information for each room via segmentation and recognition. This work can be used in other applications such as indoor robot navigation, building area and location analysis, and three-dimensional reconstruction. First, we identify and match the catalog of a mall floor plan to obtain matching text, and then we use the two-stage region growth method we proposed to segment the preprocessed floor plan. The room number is then obtained by sending each segmented room section to an OCR (optical character recognition) system for identification. Finally, the system retrieves the matching text to match the room number in order to obtain the room name, and outputs the needed room location and semantic information. It is considered a successful detection when a room region can be successfully segmented and identified. The proposed method is evaluated on a dataset including 1340 rooms. Experimental results show that the accuracy of room segmentation is 92.54%, and the accuracy of room recognition is 90.56%. The total detection accuracy is 83.81%.