bluuebunny/crossref_metadata_2025 huggingface dataset:
ОЦІНКА КЛІНІЧНОГО СТАНУ ТКАНИН ПАРОДОНТА В ОСІБ ІЗ ПСИХОФІЗІОЛОГІЧНИМИ РЕАКЦІЯМИ ДЕЗАДАПТАЦІЇ У НАЙБЛИЖЧІ ТЕРМІНИ ЛІКУВАННЯ
Authors: Pyasetska L. V. , Luchynskiy M. A.
Published: November 2018

У статті представлено результати оцінки клінічного стану тканин пародонта за даними папілярно-маргінально-альвеолярного індексу в осіб із різними клінічними варіантами реакцій психофізіологічної дезадаптації після застосування лікувально-профілактичних комплексів, які розробили та впровадили автори даної роботи, у найближчі терміни спостереження.

Мета дослідження – оцінити клінічний стан тканин пародонта в осіб молодого віку з різним психофізіологічним станом у найближчі терміни лікування (3–6 місяців) за даними папілярно-маргінально-альвеолярного індексу.

Матеріали і методи. У дослідженні взяли участь 48 пацієнтів із запальними захворюваннями тканин пародонта та 52 осіб із запально-дистрофічними захворюваннями тканин пародонта з різним психофізіологічним станом організму. Для оцінки ефективності запропонованих лікувально-профілактичних комплексів було сформовано дві основні лікувальні підгрупи.

Результати досліджень та їх обговорення. У середньому через 6 місяців після лікування значення папілярно-маргінально-альвеолярного індексу зменшувалось стосовно значень до лікування в першій основній лікувальній підгрупі у 2,0 рази та в другій основній лікувальній підгрупі – у 1,5 раза (р<0,01). В осіб із захворюваннями тканин пародонта з контрольних лікувальних підгруп через 6 місяців спостережень у результаті застосування традиційних лікувальних заходів значення папілярно-маргінально-альвеолярного індексу збільшувалось при усіх типах психофізіологічних реакцій дезадаптації і дорівнювало даним до лікування (р>0,05).

Висновки. Проведені клінічні дослідження переконливо доводять ефективність лікувально-профілактичних комплексів при лікуванні захворювань тканин пародонта у пацієнтів основних лікувальних підгруп, які ми запропонували, що підтверджено зниженням інтенсивності запальних процесів у тканинах пародонта за даними папілярно-маргінально-альвеолярного індексу в найближчі терміни спостережень.
THE INFLUENCE OF ATORVASTATIN ON OMENTIN-1 LEVEL AND INSULIN RESISTANCE IN PATIENTS WITH CORONARY ARTERY DISEASE AND OBESITY
Authors: Maksymets T. А.
Published: November 2018

Adipose tissue is a powerful endocrine organ, which synthesizes significant amount of biologically active substances – adipokines. Due to adipokine dysfunction, a spectrum of diseases associated with obesity appears, namely, coronary artery disease, diabetes mellitus, hypertension and oncology. Hyperinsulinemia and insulin resistance play a significant role in pathogenesis of cardiometabolic complications in patients with obesity. They trigger a pathological cascade of reactions leading to cardiovascular diseases. Omentin-1 possesses anti-atherogenic action and it can modify peripheral effects of insulin.

The aim of the study – to analyze changes in omentin-1 concentration and the condition of insulin resistance in patients with coronary artery disease and obesity during atorvastatin treatment.

Materials and Methods. 55 patients with obesity were examined. They had general clinical examination; blood lipids, uric acid level and liver enzymes; glycated hemoglobin, glucose, insulin with the calculation of HOMA index and omentin-1 concentration was determined. Patients were divided into two groups: the group 1 – 20 patients with obesity, who did not suffer from CAD and did not take atorvastatin, and the group 2 – patients with CAD and obesity, who took atorvastatin. Determination of these indices was performed for patients of the group 2 in dynamics in 12 months.

Results and Discussion. In the group of patients with CAD and obesity, who took atorvastatin, lipid levels were reliably lower, but levels of fasting glucose concentration, uric acid and liver enzymes were higher than in the patients who did not take the drug. Elevation of omentin-1 in blood serum was observed in 12 months in patients with CAD and obesity simultaneously with the increase in insulin level and the decrease in tissue sensitivity to it.

Conclusions. Intake of atorvastatin by patients with coronary artery disease and obesity is accompanied by elevation of insulin concentration, intensification of insulin resistance and increase in omentin-1 level.
БІОХІМІЧНІ ПОКАЗНИКИ ФУНКЦІЇ ПЕЧІНКИ У СПОРТСМЕНІВ ВИСОКОЇ ПРОФЕСІЙНОЇ МАЙСТЕРНОСТІ ПІСЛЯ ЗМАГАЛЬНОГО ПЕРІОДУ
Authors: Grushko V. С.
Published: November 2018

У процесі інтенсивної м’язової діяльності й адаптації до неї виникає перебудова в роботі усіх систем і органів, а також організму в цілому. Адаптація до фізичних навантажень визначається різноманітними функціями печінки, які забезпечують і дотримують високу працездатність спортсменів вищої професійної майстерності.

Мета дослідження – вивчити стан печінкового метаболізму в спортсменів високої професійної майстерності у період максимальних фізичних навантажень.

Матеріали і методи. З дотриманням принципів біоетики та деонтології на базі фізкультурного диспансеру було обстежено 32 практично здорових осіб і 34 спортсменів-біатлоністів високої професійної майстерності. При дослідженні використали наступні методи діагностики: імунотурбідиметричний, колориметричний ферментний, непрямий 2-ступеневий хемілюмінесцентний імуноаналіз (CLIA), проточну цитофлуориметрію і моноклональні антитіла.

Результати досліджень та їх обговорення. Визначені біохімічні показники функції печінки у спортсменів вищої професійної майстерності в період максимальних фізичних навантажень.

Висновки. Отримані дані свідчать про негативний вплив надмірних фізичних навантажень на функцію печінки.
Gomphonema bicepiformis sp. nov., a new diatom species (Bacillariophyta) from a stream in Zhejiang, China
Authors: ZHANG WEI , SHANG GUANGXIA , KOCIOLEK JHONE PATRICK , WANG LIQING , TAN HONGXIN
Published: November 2018

During a survey of freshwater diatoms from Shibadukeng stream in the Xianju County, Zhejiang Province, China, a new gomphonemoid species, Gomphonema bicepiformis sp. nov. has been recorded. The new species is diagnosed from all others in the genus based on morphology as observed with both light and scanning electron microscopy. Valves of Gomphonema bicepiformis are lanceolate with a gibbous central region. The headpole is broadly rounded, clearly capitate and the footpole is also broadly rounded, capitate. The axial area is wide, lanceolate-rhombic, broad at mid-valve, reaching 3/4 of the total breadth. There are circular to irregularly-shaped depressions in the axial area on the exterior of the valve surface often appearing as light spots in LM. The new species was compared with G. biceps, G. obstipum, G. manubrium, G. pyrenaicum, G. guayabense and G. nipponica, all of which resemble Gomphonema bicepiformis in outline, but differ from the new species in specific details of size, striae density, and extent of the axial area. This species occurs in relatively low conductivity and clean water in Zhejiang, China.
Revision of the Parasesarma plicatum (Latreille, 1803) species-group (Crustacea: Decapoda: Brachyura: Sesarmidae)
Authors: RAHAYU DWI LISTYO , NG PETER K.L.
Published: November 2018

The mangrove sesarmid crabs of the Parasesarma plicatum species-group are revised, and four distinct taxa are recognized: Parasesarma plicatum (Latreille, 1803), P. affine (De Haan, 1837), P. ungulatum (H. Milne Edwards, 1853), and P. dumacense (Rathbun, 1914). These four species are easily distinguished from congeners by the number of dactylar tubercles of the chelipeds, the shape of the male first gonopod and live coloration. Their distributions are also distinct, P. plicatum being found in the eastern Indian Ocean, P. affine in Japan, China, Taiwan, P. ungulatum throughout Southeast Asia, and P. dumacense in the Philippines.
A new Palaearctic subgenus of genus Phytoecia Dejean, 1835 (Coleoptera, Cerambycidae)
Authors: DANILEVSKY MIKHAIL
Published: November 2018

Phytoecia (Parobereina subgen. nov.) type species Phytoecia vittipennis Reiche, 1877 is described for a group of 13 Palaearctic species. Phytoecia (Obereina Ganglbauer, 1886) nom. rest. is restored as a valid name.
A Gondwanan concept of Simplimorpha Scoble (sensu lato): a step toward clarity in the generic diagnostics of global Nepticulidae (Lepidoptera)
Authors: STONIS JONAS R. , DIŠKUS ARŪNAS , REMEIKIS ANDRIUS , SOLIS M. ALMA
Published: November 2018

The genus Simplimorpha Scoble is recognized for the first time from South America. We describe a subgenus, Myrtinepticula Stonis & Diškus, subgen. nov., for three new species from the southern Andes (Chile and Argentina): Simplimorpha (Myrtinepticula) cercaria Diškus & Stonis, sp. nov., S. (M.) nielseni Remeikis & Stonis, sp. nov., S. (M.) sapphirella Remeikis & Stonis, sp. nov.; and one new species from the southwestern Amazon (Peru): S. (M.) kailai Stonis, sp. nov. We provide a pictorial differentiation scheme for Simplimorpha Scoble and Pectinivalva Scoble. We synonymize the recently erected, predominantly Australian Menurella Hoare, syn. nov. and Cosanovula Hoare, syn. nov. with Pectinivalva Scoble. We also revise the taxonomic status of the Australian Roscidotoga Hoare as a subgenus of Simplimorpha which now exhibits a Gondwanan distribution in the Southern Hemisphere, with the presence of a single species in the Mediterranean. All new taxa are illustrated with photographs of the adults and the genitalia; the leaf mines of Simplimorpha (Myrtinepticula) nielseni sp. nov. are also provided.
New species of Anaptomecus Simon, 1903 (Araneae: Sparassidae) from Colombia, with an identification key for all known species of the genus
Authors: GALVIS WILLIAM , RHEIMS CRISTINA ANNE
Published: November 2018

The huntsman spider genus Anaptomecus was proposed by Simon (1903) to include the type species, A. longiventris Simon, 1903, described from a juvenile male collected in Cayambé (San Pedro de Cayambé), Pichincha, Ecuador. Mello-Leitão (1940) described a second species, A. rufescens, from a female collected in Essequibo River, Guyana. The genus remained unstudied until the early 2000’s when Jäger et al. (2009) described the adult male and female of A. longiventris and transferred A. rufescens to Sparianthina Banks, 1929. In this same paper, the authors described A. temii Jäger, Rheims & Labarque, 2009, based on a male from Panama, and A. levyi Jäger, Rheims & Labarque, 2009, based on a female from Colombia. A few years later, Guala et al. (2012), increased the number of known species with the descriptions of A. paru Guala, Labarque & Rheims, 2012 and A. suni Guala, Labarque & Rheims, 2012, both based on males and females from Ecuador. Thus, Anaptomecus currently includes five species and is distributed in southern Central and northern South America, from Costa Rica to central Ecuador (Puerto Napo, Napo) (World Spider Catalog 2018).
Redescription of the Central American genus Moribaetis Waltz & McCafferty 1985 (Ephemeroptera, Baetidae)
Authors: KLUGE NIKITA J. , VEGA JUAN A. BERNAL
Published: November 2018

A new definition for the genus Moribaetis Waltz & McCafferty 1985 is given. Its type species, Moribaetis maculipennis (Flowers 1979) is redescribed based on male and female imagoes reared from larvae near the type locality in Panama. Larvae, formerly wrongly attributed to Moribaetis salvini (Eaton 1885), and a male imago, formerly wrongly attributed to Moribaetis macaferti Waltz 1985, belong to a new species Moribaetis latipennis sp. n., which is described here based on a male imago reared from larva in Panama. Both species, M. maculipennis and M. latipennis sp. n., are distinct from M. salvini, which is known as a single male imago (lectotype) from Costa Rica. All other species, formerly attributed to Moribaetis, are excluded from this genus; a new combination Caribaetis macaferti comb. n. is proposed for the species originally described as Moribaetis macaferti Waltz (in Waltz & McCafferty) 1985, and a new combination Baetis (Rhodobaetis) mimbresaurus comb. n. is proposed for the species originally described as Moribaetis mimbresaurus McCafferty 2007.
Revision of the genus Pseudolebinthus (Orthoptera, Gryllidae, Eneopterinae) with the description of a new species from Southeast Africa
Authors: JAISWARA RANJANA , DONG JIAJIA , ROBILLARD TONY
Published: November 2018

Pseudolebinthus is an intriguing genus of the tribe Xenogryllini with a distribtuion restricted to southeast Africa and characterized by unique morphological features such as asymmetrical male forewings and harp veins shaped as elongated balloons. It is sister group to the widely distributed genus Xenogryllus and has been known by two species, P. africanus Robillard, 2006 and P. whellani Robillard, 2006. The genus was initially diagnosed based exclusively on male morphological features. In this study, we add a new species to the genus, P. gorochovi Robillard sp. nov. and revise the diagnostic features using both male and female characters. We also update identification keys for the species of the genus.
Surface-Enhanced Raman Spectroscopy (SERS) of Mancozeb and Thiamethoxam Assisted by Gold and Silver Nanostructures Produced by Laser Techniques on Paper
Authors: Atanasov Petar A. , Nedyalkov Nikolay N. , Fukata Naoki , Jevasuwan Wipakorn , Subramani Thiyagu , Terakawa Mitsuhiro , Nakajima Yasutaka
Published: November 2018

Advanced gold (Au) and silver (Ag) nanostructures were produced by laser techniques on printer paper substrate. Surface-enhanced Raman spectroscopy (SERS) analyses of the fungicide mancozeb (Dithane DG) and insecticide thiamethoxam (Aktara 25 BG) in quantities smaller than usually applied in agricultural medicine were performed for the first time assisted by the structures fabricated. The investigations and results show an easy alternative and cheap way to detect small amounts or residue of harmful environmental pollutants, which has a direct bearing on food quality and thus on human health.
An Exploration of Turkish Prospective Teachers’ Teaching Competencies through the Analysis of Their Pedagogical Content Knowledge Documentations
Authors: Soysal Y. , Radmard S.
Published: November 2018

This study explores the initial teaching competencies of 211 prospective teachers (PT) through an examination of their pedagogical content knowledge (PCK) documentations that were obtained through a PCK Construction Task. The scored data were subjected to a factor analysis, and two factors of PCK were extracted. ANOVA results showed that even though all teaching groups were relatively competent in documenting their knowledge of taught content and knowledge of instructional strategies and representations, they were less knowledgeable with regard to their students’ understanding. Regarding these two factors, the PTs attending the Turkish Language Teaching (TLT) program were also found to be at lower levels compared with the other three teaching programs. Through the semi-structured interviews with the faculty members, it was concluded that performance of the academics providing the TLT program was one of the reasons for the lower levels of PCK documentations of the PTs.
Antisensitization in the Cases of Organ Transplants
Authors: Silló-Seidl Georg
Published: November 2018

Author describes the possibility of antisensitization concerning ovarian and tubal transplantation in women. Neither clinical nor laboratory signs were found until 9 months after the operation.
Risultati a lungo termine della chemioterapia adiuvante con Cisplatino e Methotrexate nel carcinoma infiltrante della vescica dopo cistectomia
Authors: Scattoni V. , Rovellini P. , Bottanelli A. , Pavia G. , Baroni G.P. , Sciaraffia G. , Rigoni L. , Toia G. , Marcelli G.
Published: November 2018

From January 1985, 28 patients affected by locally advanced bladder cancer (pT2-pT4a, pNx-N0-N1-2, MO) underwent 4 planned cycles of adjuvant chemotherapy with cisplatin (70 mg/m2 on day 1) and methotrexate (40 mg/m2 on days 8 and 15) after cystectomy. Gastrointestinal toxicity and agranulocytosis were so severe that only 50% of the patients completed the four planned cycles. After a median follow-up of 36 months (range 9-89 months), the overall 5-year disease-free survival rate of 26 evaluable patients was 32%. None of the patients with pathological evidence of lymph node metastases survived longer than 5 years, while the 5-year disease-free survival rate of the patients without nodal involvement was 55%. Seventy-five percent of progressions (12/16) were identified within 24 months. Only 28% of the patients submitted to salvage chemotherapy with an M-VAC regimen after progression showed a partial response of short duration to chemotherapy.
Valore Predittivo del Mapping Prostatico Nella Valutazione Preoperatoria Del Volume Della Neoplasia Prostatica: Studio Ecografico ed Anatomopatologico su 25 Pazienti Sottoposti a Prostatectomia Radicale Retropubica
Authors: Casolari E. , Cesolari R. Rossi , Nigrisoli E. , Cavazza A. , Zanonp P. , Leoni S.
Published: November 2018

Quantitative tumour volume is reported to be the single most important morphologic predictor for lymph node metastases and distant spread in the individual patient with prostatic cancer. 25 patients with histologically proved prostatic cancer underwent Prostatic Mapping before Radical Retropubic Prostatectomy. Surgical specimens were processed and prostatic cancer volume was calculated according to abbreviated standard procedure that avoids the serial blocking of prostatectomy specimens required by standard techniques. Our study demonstrated a strong correlation between Prostatic Mapping categories and prostatic cancer volumes. This ability of Prostatic Mapping to estimate preoperatively the tumour volume may be a useful clinical tool to help guide surgical therapy and assess prognosis.
Spondiloartrite Acuta: Rara Complicanza in Corso di Terapia Endovescicale con BCG
Authors: Maccatrozzo L. , Fandella A. , Merlo F. , Mangano M. , Legovini P. , De Menis E.
Published: November 2018

Endovesical administration of BCG is currently considered the most effective therapy and prophylaxis for bladder carcinoma in situ. Arthritis has been noted during this therapy, due to an immunitary type reaction rather than a localisation of the mycobacterium. We report the case of acute arthritis in a 52-year-old man undergoing endovesical treatment with BCG for multiple superficial carcinoma of the bladder, who presented a typical picture of spondyloarthritis. The positivity of the HLA-B27 histocompatibility of the antigen in the patient suggests that also with arthritis during BCG therapy, this antigen confers susceptibility at the onset of a spondyloarthritis, rather than other articular clinical pictures.
Oncocitoma Renale: Una Possibilità per una Terapia Conservativa
Authors: Benecchi L. , Bordinazzo R. , Catania G. , Privitera O.
Published: November 2018

Renal oncocytoma cells differ from those of other renal carcinomas. They arise from the intercalated cells of the collecting tubules. Originally it was considered a benign neoplasm, but it is now believed that it can have a limited but real malignant or metastatic potentiality. Between 1988 and 1992, 53 néphrectomies were performed in our department of urology for renal parenchymal carcinomas. 5 cases were diagnosed as oncocytomas (9.4%). 4 of these occurred in men (80%) and 1 in a woman (20%). The age of the patients is between 45 and 70 years old, with an average age of 60.6 years. At present the therapeutic approach of renal oncocytoma is no different from that of renal cell carcinoma. Standard therapy is radical nephrectomy. In the presence of small and peripheral well-encapsulated renal tumours the techniques of nephron sparing are preferred. In fact, as referred by Steinbach, with conservative surgery, good results were obtained even after 5 years (from 84% to 96%), not only in the imperative indication (tumours found in an anatomically or functionally solitary kidney or bilateral renal tumours) but even in the elective indication (patients with a small solitary mass lesion in the kidney and a normal contralateral kidney).
A Proposito di Tre Casi di Pielonefrite Multifocale Ascessualizzata: Diagnosi ed Evoluzione
Authors: Petitoni G. Ricci , Lazzari G.M. , Sermasi O. , Fini M. , Vagliani G.F. , Di Silverio A.
Published: November 2018

Renal bacterial infection spans a continuum of severity from uncomplicated acute pyelonephritis to frank abscess formation. It can be a multi-focal process, with different portions of the kidney exhibiting different degrees of inflammation. The radiologic diagnosis of acute renal infections is based upon IVU, US and CT. In this investigation, the contribution of IVU, US and CT is evaluated in 3 patients with acute multifocal pyelonephritis and renal abscesses. The lack of specificity of IVU and the high false negative rate of US make them unsatisfactory diagnostic tools for patients clinically suspected of having multifocal pyelonephritis or renal abscess. CT is more sensitive for the detection of acute renal inflammatory diseases and for defining the extent of disease, thereby helping programme early and accurate therapy.
Emangioma epitelioide perineurale del fascio nervo-vascolare dorsale del pene. Esempio di rara localizzazione
Authors: Pittaluga P. , Moretti M. , Cichero A. , Malcangi B. , Varaldo M.
Published: November 2018

We report the case of a 32-year-old man with penile pain during erection. Examination revealed nodular lesion at the base of the penis, which ultrasound indicated as hypoechoic. At surgical approach we found a grey nodule between the fibres of the dorsal nerve of the penis. Histological examination revealed epithelioid hemangioma.
Scuoiamento Penoscrotale Post-Traumatico: Valutazione Plastica e Uro-Andrologica Post Intervento Ricostruttivo
Authors: Beretta G. , Marzotto M. , Di Giuseppe P. , Zanollo A.
Published: November 2018

A case of surgical reconstruction after penoscrotal skin avulsion is described. Penile coverage was gained by two full thickness grafts helicoidally placed to avoid retractions. Scrotal reconstruction was carried out in two steps after testis subcutaneous implantation, with axial flaps expanded in the abdominal region. The procedure has the advantage of ensuring vitality of the flaps; it avoids patient discomfort produced by perineal expansion, while cosmetic appearance is satisfactory and normal sexual function is restored.
Liposarcoma Dell'epididimo: Descrizione di un Caso e Revisione Della Letteratura
Authors: Monica B. , Salsi P. , Minari R. , Barbieri A. , Poletti F.
Published: November 2018

We report a case of epididymis liposarcoma in a 76-year-old man, who about 6 months before had noted an oval, painless, well delimitable, non-light transmitting right hemiscrotal swelling apparently separated from the didymus. There was no inguinal lymphoadenopathy. A radical orchiectomy was performed. On the basis of clinical staging, that displayed neither local involvement, nor distant metastases, we believe, in accordance with literature, this surgical management can achieve definitive cure; other resolutions will be undertaken in case of relapse.
Gangrena acuta dei genitali di Fournier: Descrizione di un caso
Authors: Invernizzi S. , Locatelli G. , Cappoli S. , Butti A. , Santini R. , Carcaterra A.
Published: November 2018

The Authors describe a case of Fournier's disease and summarise the main etiopathogenic hypotheses and the therapeutical approaches to this urological and, at the same time, dermatological emergency, which has to be tackled quickly with competence but which is, however, lethal in many cases.
L'utilità del color doppler nella patologia prostatica: Nostra esperienza
Authors: Veneziano S. , Querzé R. , Mannini D. , Carcello A. , Sabattini A. , Luna P.
Published: November 2018

The authors report their experience with color Doppler (CD), associated with endorectal US in the study of prostatic diseases. They examined 35 patients with benign prostatic hyperplasia, 27 with prostatitis, 21 with prostatic carcinoma and 5 young healthy volunteers. In the 35 cases of benign prostatic hyperplasia, CD proved to be of limited usefulness, although ruling out concurrent, inflammatory or neoplastic disease. In the 27 cases of prostatitis, CD proved to be particulary useful in acute or chronic recurrent cases. In those cases the method showed marked color increase at the periurethral site or in the area close to the seminal vesicles, also allowing follow-up after therapy. In the 21 patients with prostatic carcinoma, CD allowed the demonstration of 2 tumours that were isoechoic at endorectal US with grey scale. In both cases it was possible to make a “color guided” biopsy.
PSA ed età
Authors: Brigato R. , Griffa D. , Caputo A. , Surleti D. , Laudi M.
Published: November 2018

166 patients between 50-86 years old have been examimed for PSA immunoenzymatical determination (prostatic specific antigen). This group of patients has been divided into classes according to age (50-60, 61-70, 71-80) and urological pathology (107 with benign prostatic hypertrophy; 12 with histologically defined prostatic carcinoma without therapy; 15 with prostatic carcinoma incidentally determined after prostatic adenomectomy for benign prostatic hypertrophy and 32 patients with no prostatic urological pathology). We wanted to investigate how the PSA is correlated with age. The results of this study could demonstrate the importance of age for PSA interpretation. The low sensibility of this marker for the diagnosis of prostatic incidental carcinoma and low-class prostatic carcinoma could be shown with this study.
Trattamento con laser infrarosso endouretrale delle prostatiti croniche abatteriche riacutizzate
Authors: Strada G. , Baccalin A. , Frea B. , Scardino E. , Musci R. , Rocco F.
Published: November 2018

The Authors present a new infrared laser device with endourethral atraumatic optic fiber capable of effectively treating patients with newly acute chronic prostatitis. Cost-benefit ratio is excellent and the method is minimally invasive.
Il penogramma radioisotopico dinamico con nitroglicerina sublinguale nella diagnostica non invasiva dell'impotenza
Authors: Casucci R. , Broggini P. , Malvestiti G.M. , Ghezzi A. , Scotti S. , Casagrande S. , Jallous H. , Marandola P. , Roggia A.
Published: November 2018

Nuclear medicine techniques may be used to test vasculogenic impotence. Dynamic radioisotope penogram with 0.3 mg sublingual nitroglycerin was performed in 50 impotent patients. The penogram index (Ip) and the time required to reach peak activity (Tp) was calculated. Ip was useful to differentiate vasculogenic and psychogenic impotence. The radioisotope penogram is a simple, less invasive and valuable screening test in the identification of vasculogenic impotence.
Holter delle vie urinarie: Indagine integrata per il monitoraggio continuo dell'alto e del basso apparato urinario. Tecnologia e metodologia d'indagine
Authors: Cisternino A. , Artibani W. , Caruso A. , Valotto C. , Calpista A. , Passerini G. , Pagano F.
Published: November 2018

We present a new holter system that allows continuous and simultaneous monitoring of both the upper and lower urinary tract for a true maximum recording of 24 hours. Such investigation appears promising for a detailed description of dilated, obstructed and refluxing systems.
Tasca retto-sigmoidea (Mainz Pouch II) modificata: Nostra esperienza
Authors: Sevin G. , Gezeroglu H. , Pacchiele R. , Carbone A.
Published: November 2018

Sigma-rectum pouch (Mainz Pouch II) operation, which is a detubularized modification of the well-known ureterosigmoidostomy is becoming a popular alternative of urinary diversion in selected patients. 12 male patients underwent this operation due to locally invasive bladder tumours or incurable urethral strictures and fistulas. The pouch was tailored using 12 cm of sigmoid colon and rectum and performing a side to side anastomosis of the detubularized bowel in an inverted U shape. The new formed pouch was fixed onto the posterior peritoneum so that traction affecting the pouch was minimized. Postoperative radiological analysis revealed no obstruction or ureteral reflux. Urodynamic studies revealed low pressure, high volume reservoirs. Only 1 patient had reservoir wall contractions of low amplitude during filling. Although early postoperative blood chemistry did not reveal any metabolic abnormality, at long-term follow-up some patients showed important electrolyte and acid-base disorders.
L'ecografia transrettale ha un ruolo predittivo nella neoplasia prostatica localizzata?: Is transrectal ultrasonography useful in predicting localised prostatic cancer?
Authors: Zambolin T. , Pezzotti G. , Botturi A. , De Luca V. , Giambroni L. , Cancarini G. , Tralce L. , Tardanico R. , Moretti R. , Cunico S. Cosciani
Published: November 2018

Transrectal ultrasonography and pathological data were compared in 72 patients submitted to radical prostatectomy for prostatic cancer. The tumour was hypoechoic in 41 patients (57%) and hyperechoic in 2 patients (3%). In 29 patients (40%) the neoplasia was isoechoic and could not be identified by means of ultrasound. A statistically significant correlation (p < 0.001) was observed between Gleason's score and the size and echogenicity of the neoplasia. A high percentage of tumours, even those of a large size and with a high grading, cannot be identified by transrectal ultrasonography. Transrectal echography alone is therefore unreliable in diagnosing prostatic cancer. In our experience 29% of tumours larger than 1 cm were not identified.
Significato e utilità clinica dell'Antigene Prostatico Specifico nella stadiazione del carcinoma prostatico. Valutazione su 70 prostatectomie radicali retropubiche: Utility and clinical value of Prostate Specific Antigen in the staging of prostatic carcinoma. A study on 70 radical prostatectomies
Authors: Valerio S. , Antoniazzi G. , Petterle V. , Scarpa V. , Fornasiero G.F. , Bassi E.
Published: November 2018

Prostate specific antigen is the most important tumour marker in the study of prostatic cancer. The role of PSA in the management of prostatic carcinoma has been clarified in the diagnostic and prognostic stage, but several controversies persist over prediction of final pathological stage. We present our experience and discuss our results in 70 radical prostatectomies.
La patologia traumatica del rene: Nostra esperienza in tema di stadiazione e di indicazione chirurgica: Renai trauma: Our experience in clinical staging and surgical treatment
Authors: Meazza A. , Nebulone V. , Franzoso F. , Sorboli G.
Published: November 2018

We studied in retrospect 144 patients suffering from blunt trauma of the kidney in order to better define the indications for radiological assessment and surgical treatment. If staging is fundamental, most of ail for high-risk patients, it is our opinion that urography must still be considered the decisive X-ray test to assess the renal parenchyma and the urinary tract of the kidney as well as the integrity of the adelph. In cases with micro hematuria and in absence of shock, ultrasound diagnosis is used in place of urography, whereas computerized tomography of the abdomen must be restricted to the cases of renal autoamputation, urohematic extravasation and suspected intraperitoneal injuries. We adopt conservative treatment for all those injuries to the renal parenchyma which respect the urinary tract, whereas we recommend emergency surgical treatment in those cases involving traumatism of the pedicle or kidney fragmentation. We instead postpone surgical treatment in all other cases, following spontaneous haemostasis of the renal space. We believe that both the rate of death and invalidating consequences from traumatic pathology of the kidney can be significantly reduced where there is qualified pre-hospital assistance and cooperation with a medical facility offering rapid detailed diagnosis and specific medicosurgical treatment.
Patologia genitale nei giovani in servizio di leva: Esperienze del Policlinico Militare di Padova: Genital pathology in youths doing their military service: Experiences from the Military Hospital of Padua
Authors: Mammana G. , Errante D. , Galozzi R.
Published: November 2018

The Medical Corps is a privileged observatory of the various pathologies found in youths. This is even more evident in the case of a Military Hospital like that in Padua, which serves the north-east regions of Italy, where there is still a strong military presence. The high number of patients observed at the hospital, suffering from genital pathologies and from varicocele in particular, has led to the comparison of the different types of preoperative staging and treatment, both surgical and anesthesiological, of these pathologies. Apart from presenting the epidemiological data of genital diseases, the following work also highlights the importance of careful pre-operative clinical-instrumental staging of varicocele and the satisfying results that can be obtained in treating the same with high ligature of the gonadic vessels under local anesthesia. There are also precise indications as to the use of alternative surgical techniques (microanastomosis, ligature by laparoscopic approach, etc.).
Criteri e basi teoriche per un corretto approccio allo screening presintomatico delle malattie neoplastiche: Criteria and theoretical bases for a correct approach to presymptomatic screening of neoplastic diseases
Authors: Di Silvio L.
Published: November 2018

The different criteria to be taken into consideration when carrying out presymptomatic screening of neoplastic diseases are given. Screening is an operation of secondary prevention and can be divided into: 1) mass screening 2) selective (or aimed) screening 3) multifascia screening (check up). The Author gives the fors and againsts of the above types of screening and concludes that they can lead to: 1) only a prolungation of the lead time 2) a more favourable life expectation 3) a normal life expectation with death due to the neoplasm 4) death for natural causes and not for the tumour 5) early death (iatrogenic). The general criteria laid down by the W.H.O. on the suitability of submitting a population to screening are: a) the pathology to be investigated must be an important problem both for health and socially b) a diagnostic protocol must be available for subjects who have a positive test result, as well as an effective treatment protocol for the diagnosed cases c) the investigated pathology must be characterised by a recognisable stage, latent or with early symptoms d) screening methods must be easy to carry out with no risks involved e) the screening must be acceptable for the invited population f) the natural history of the neoplasm must be sufficiently well-known g) the parameters of normality, allowing the positive patients to be distinguished from the negative ones, must be very clear h) assessment of the cost/benefit ratio i) the activity of early diagnosis must be a continuing and not an irregular service, on the basis of established protocols I) the availability of economic, staff and organisational resources must be guaranteed. In any case, the Author proposes that the screening programme be checked in terms of sensitivity (capacity to select the truly ill people), specificity (capacity to select the healthy ones) and predictive value (% value of test reliability).
Basic and advanced urodynamics in benign prostatic hypertrophy
Authors: Camuffo C. , Faccioli F. , De Marchi G. , Guatelli S. , D'incà G. , Bertoldin R. , Drei G.N. , Meneguolo M. , Guazzieri S.
Published: November 2018

BPH patients may be asymptomatic or symptomatic and the latter with or without obstruction. Symptoms may be independent of the obstruction. The endoscopic or surgical ablation of the enlarged gland has a percentage of failure in all reports. The urodynamics study including uroflowmetry, pressure flow study with application of nomogram for the obstruction provides a certain diagnosis of obstruction in the majority of cases.
Acute urinary retention in the female by autonomic neuropathy
Authors: Pezzotti G. , Simeone C. , Capra R. , Cunico S. Cosciani
Published: November 2018

We report a case of acute autonomic neuropathy without any signs of peripheral neuropathy, which presented in a young woman with acute urinary retention. Exclusion of other possible etiologies, clinical indications and a precise diagnostic routine enabled us to recognise this uncommon but important pathology.
Laparoscopy in urology after five years: Urinary incontinence
Authors: Breda G. , Tamai A. , Silvestre P. , Gherardi L. , Xausa D. , Giunta A.
Published: November 2018

The authors have reviewed the literature on stress urinary incontinence (SUI) treatment by laparoscopy or pelvioscopy. They report their experience with the pubo-vaginal percutaneous colposuspension assisted by pelvioscopy. Out of 22 patients they had a total correction of incontinence in 15 patients (68.12%) with an average follow-up of 18.6 months. They also report their first experience with the Retzius plasty of Manhes by laparoscopy (average follow-up 13 months, 3/4 patients treated are continent, 1/4 SUI with high stress). They conclude that laparoscopy and pelvioscopy treatments can be a valid alternative to tradizional surgery if performed on selected patients.
Laparoscopic “en-bloc” ligation of spermatic veins
Authors: Trombetta C. , Savoca G. , Liguori G. , Tamai A. , Siracusano S. , Belgrano E.
Published: November 2018

Laparoscopic varicocelectomy is suggested only for II-III grade bilateral varicocele. The optical magnification granted by videosurgical techniques, prevents damaging testicular arteries; this possibility, however, requires a considerable amount of time. We performed a laparoscopic “en-bloc” ligation without sparing the artery on 13 patients with bilateral varicocele in order to assess eventual changes in gonadal volume. 10 patients underwent bilateral “en-bloc” ligation of spermatic vessels with an average operating time of 21 minutes. In 3 other patients, “en-bloc” ligation was performed on the right side while on the left side the artery was identified and saved; in these cases the average operating time was 33 minutes. After an average follow-up period of 19 months no cases of testicle atrophy nor of hydrocele were reported. ColorDoppler sonography, performed 3 months later on the 10 patients treated by bilateral “en-bloc” ligation, showed no persistent reflux. No case of homolateral persistent reflux was encountered in the 3 patients who underwent only right-side “en-bloc” ligation, but on the left side, where selective ligation had been performed, persistence of reflux was registered in one patient. Our experience has confirmed that laparoscopic “en-bloc” ligation of the internal spermatic pedicle, sparing vasa deferentia, prevents the persistence of reflux in all cases and allows a reduction in operating time. The opportunity of treating a pathology like bilateral varicocele by means of laparoscopy, which requires general anaesthesia, needs further confirmation and a larger number of case histories.
L'anestesia combinata epidurale e generale versus l'anestesia generale nel paziente urologico anziano ad alto rischio. Uno studio clinico prospettico e randomizzato: Combined epidural and general anaesthesia versus general anaesthesia in high-risk urological elderly patients. A prospective randomised trial
Authors: Galimberti G. , Berlot G. , Iscra F. , Gullo A.
Published: November 2018

Twenty-eight elderly high-risk (ASA 3) patients undergoing elective major urological surgery were prospectively randomised to receive either combined epidural and general anaesthesia (CEGA) or general anaesthesia (GA). The use of intraoperative vasopressors was significantly higher in the CEGA group (p<0.001). There was no significant difference between groups with regard to blood loss, volume replacement, postoperative complications and mortality. The CEGA allowed saving of inhalatory anaesthetic agents (p<0.001) and a shorter total hospital stay than GA (p<0.0044). The authors conclude that the CEGA exerted a significant beneficial effect on the intraoperative outcome in a group of high-risk surgical patients.
Alternative Mini-Invasive Nelle Ostruzioni Cervico-Uretrali Dell'anziano: La Laserterapia: Mini-Invasive Alternatives in Cervico-Urethral Obstructions in the Elderly: Laser Therapy
Authors: Monica B. , Barbieri A. , Sebastio N. , Salsi P.
Published: November 2018

An ageing general population, increase in average life span and prevailing benign prostatic hypertrophy bring an increasing number of elderly men to surgery for cervico-urethral obstruction. Given the small but significant morbidity of TURP, recently new mini-invasive techniques have been introduced for BPH, laser therapy being the most popular. The authors report on the different methods for delivering laser energy to the prostate, discussing the benefits and defects. They also present their personal experience with 44 patients aged over 75 years subjected to Nd:YAG laser prostatectomy from 1992 until today. In these patients transurethral laser evaporation, as suggested by Narayan and al., produced significant symptomatic and clinical results with low morbidity and invasiveness. The authors therefore believe that this kind of therapy may improve management of the elderly patient with BPH.
Exchange Rate, Uncertainty and Foreign Direct Investment Inflow in West African Monetary Zone
Authors: Eregha Perekunah B.
Published: November 2018

Exchange-rate movements are mostly unpredictable, and this tends to affect both trade and foreign investment flows. This is because foreign investors are unclear on the returns to investment decisions in such cases. Hence, this study examines the effect of exchange rate, its volatility and uncertainty on foreign direct investment (FDI) inflow in West African monetary zone (WAMZ). The study covers the period1980–2014, and the within estimator for the fixed effect model is employed. The study accounts for both exchange rate volatility and uncertainty measures which are anticipated and unanticipated exchange rate innovations measures, respectively. The results show that exchange-rate movements in WAMZ countries are more of unanticipated than anticipated innovations in affecting FDI inflow. Therefore, policies aimed at targeting exchange-rate stability are essential in the WAMZ countries since investors are profit maximizers; hence, investment uncertainties must be kept as low as possible. Also since WAMZ export sectors are primary products based, policies should be geared towards the diversification of the export sectors to combat unanticipated global shocks from commodity prices movement in having an effect on the exchange rate through the foreign exchange reserve channel.
Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma
Authors: Hughes Abigail , Dhoot Gurtej K
Published: November 2018

A number of human and canine hepatocellular carcinoma tissues showed clear signs of hypoxia indicated by HIF1α-activation and the presence of large clusters of cells resembling erythrocytes at different stages of nuclear elimination without any defined endothelial cell lining or blood vessel walls. Differentiated erythrocytic identity of such cells in hepatocellular carcinoma tissues was apparent from their non-nucleated and evolving basophilic to eosinophilic staining characteristics. In addition to the fully differentiated non-nucleated mesenchymal cell clusters, the onset of erythroblastic transdifferentiation was apparent from the activation of Glycophorin A, a marker of erythrocytic progenitors, in some epithelial cancer cells. Activation of canonical Wnt signalling in such tumours was apparent from the expression of Wnt2 ligand and active β-catenin translocation into the nucleus indicating Wnt signalling to be one of the key signalling pathways participating in such cell transdifferentiation. Sonic hedgehog and bone morphogenetic protein signalling along with Sulf1/Sulf2 activation was also observed in such hepatocellular carcinoma tissue samples. The presence of stem cell markers and the cell signalling pathways associated with erythropoiesis, and the detection of messenger RNAs for both α and β haemoglobins, support the assumption that hepatocellular carcinoma cells have the potential to undergo cell fate change despite this process being dysregulated as indicated by the lack of simultaneous generation of endothelial cell lining. Lack of blood vessel walls or endothelial cell lining around erythrocytic clusters was confirmed by non-detection of multiple blood vessel markers such as vWF, CD146 and smooth muscle α-actin that were clearly apparent in normal and unaffected adjacent regions of hepatocellular carcinoma livers. In addition to the activation of Glycophorin A, transdifferentiation of some hepatocellular carcinoma hepatocytes into other cell fates was further confirmed by the activation of some stem cell markers, for example, NANOG and OCT4 transcription factors, not only by reverse transcription polymerase chain reaction but also by their restricted expression in such cells at protein level.
“The brilliance of perfection” or “pointless finish”? What virtuosity means to musicians
Authors: Ginsborg Jane
Published: November 2018

The concept of virtuosity has been explored by music historians and theorists from disciplines ranging from aesthetics and anthropology to semiotics. Its history goes back to ancient times, although it is often thought to culminate in the 19th century with Liszt and Paganini. Many historical sources quote well-known performers and composers but little is known as to how music students and professional musicians define virtuosity today, and what it means to them as performers and audiences. The present study was exploratory, employing a mixed methods approach. A total of 102 musicians provided open-ended responses to a short questionnaire. A keyword-in-context analysis of content was undertaken, followed by a more in-depth thematic analysis. Five main themes emerged: characteristics of virtuosity; relationship between virtuosity and (“magical”) music making; aspirations towards virtuosity; how virtuosity is achieved; and communication. Responses from students and professionals were compared and are discussed with reference to historical and current theoretical models.
Marx 200 years on
Authors: Dixon Robert
Published: November 2018

This year marks the 200th anniversary of the birth of Karl Marx, the last of the classical political economists. This article aims to mark the occasion by drawing attention to some of his key works in economics and to present some of his ideas in a way that will make sense to readers not familiar with or very much interested in the complexities of the labour theory of value. I begin with a brief biography and a summary of his main works in economics. I then explore in some detail ideas related to the economic surplus, unpaid labour and exploitation, and attempt to tease out the implications of his analysis for the determination of the wage share. While I argue that Marx has not succeeded in providing adequate theoretical support for his prediction that the wage share will fall as capital accumulates, he has nonetheless provided a very interesting and insightful collection of ideas by which we may, even today, approach a wide range of issues relating to production and distribution.