bluuebunny/crossref_metadata_2025 huggingface dataset:
MYCETOMA OF THE FOOT: A RARE CASE OF MADURAMYCOSIS IN A SUDANESE MALE LIVING IN SAUDI ARABIA
Authors: Al Matroudi Ghadi , Al Dhowyan Noura , Al Dakhil Lama , Al Suhaibani Shoug , Al Senaid Thana , Al Khezzi Amjaad , Al Sulaim Lamees
Published: December 2023

Mycetoma, a rare tropical disease, manifests as chronic subcutaneous granulomatous lesions predominantly found in the mycetoma belt, encompassing Sudan, Mexico, and India. This study offers a comprehensive discussion and literature review, delving into the historical evolution of mycetoma since its initial description as Madura foot in 1832. Clinical presentation typically involves painless subcutaneous masses, sinus tracts, and discharges, with the foot being the primary site of affliction. In the context of this broader discussion, we present the case of a 52-year-old Sudanese male residing in Saudi Arabia, who presented with a chronic, painful swelling in the right big toe. The subsequent diagnosis revealed Maduramycosis, providing a nuanced perspective within the clinical landscape. Diagnostic methodologies rely on clinical features, imaging, and cultures to identify causative microorganisms. Actinomycetoma, induced by gram-positive filamentous actinomycetes, demonstrates responsiveness to antibiotics like trimethoprim-sulfamethoxazole or high-dose penicillin G. Conversely, eumycetoma, associated with Mudrellamycetomatis, exhibits poor responses to antifungals, necessitating surgical interventions ranging from excision to amputation. This study underscores the dynamic epidemiology of mycetoma, with emerging cases noted outside traditional endemic regions. By unraveling the clinical enigma surrounding mycetoma, this research contributes to an enhanced understanding of this complex disease, paving the way for improved diagnostic and therapeutic modalities. Ongoing research remains pivotal to addressing the challenges posed by mycetoma and advancing global efforts to manage and prevent its impact on affected populations.
Assessment of effective doses for fluoroscopy-guided balloon dilatation of benign esophageal strictures in pediatric medicine
Authors: Kapyrina Yu. N. , Vodovatov A. V. , Puzyrev V. G. , Komissarov M. I. , Aleshin I. Yu. , Golikov V. Yu. , Orel V. I.
Published: December 2023

Interventional examinations are associated with high levels of patient exposure per examination, which makes it particularly important to monitor individual patient doses and to assess radiation risks. The aim of this study was the assessment of effective doses for fluoroscopy-guided balloon dilatation of benign esophageal strictures, whichwasperformedonpediatricpatientsaged 1 to 2 yearsatthe Departmentof Radiosurgical Methodsof Diagnosis and Treatment of St. Petersburg State Pediatric Medical University. Patient exposure patterns were basedonourowndatacollection.    Thecalculationofeffectiveandorgandosesofpatientsnormalizedbythevalue of the dose area product measured during the study was carried out using PCXMC 2.0 software. The conversion coefficients from the dose area product to the effective dose were calculated using tissue weighting coefficients from the ICRP Publications 60 and 103 their values were 10.7 and 11.7 µSv/cGy cm2, respectively. The results of verification of the method indicated that the use of inappropriate conversion coefficients leads to an almost double underestimation of children’s effective doses. Differences in the values of conversion coefficients are significant and are explained by differences in voltage, source to image distance, and irradiation field size. A simplified model of patient exposure was proposed, which is described by a single irradiation field. The assessment of effective doses using multi-field and single-field irradiation model shows comparable results, which allows using the differentiated approach to the assessment of radiation doses of patients.
Results of modern radiation-hygienic surveys of settlements of Bryansk Oblast of the Russian Federation bordering the Republic of Belarus. Part 2: Population’s food preferences (diet)
Authors: Romanovich I. K. , Bazyukin A. B. , Bratilova A. A. , Bruk G. Ya. , Varfolomeeva K. V. , Drozdova E. A. , Zhesko T. V. , Kaduka M. V. , Kormanovskaya T. A. , Kravtsova O. S. , Kudryashov A. V. , Ladik A. A. , Lalayan V. A.
Published: December 2023

This study presents results of radiation-hygienic surveys of the Bryansk Oblast settlements bordering the Republic of Belarus. The data were obtained in the course of implementation of measures of the “Program of joint activities of Russia and Belarus within the framework of the Union State for the protection of the population and rehabilitation of the territories affected by the Chernobyl NPP accident” in 2019–2022. The second part of the study presents structure of population’s food preferences (diet). A general description of the diets of residents is given and the main types of local food products at the present stage of the radiation accident are identified. The current levels of consumption of locally produced food (and products of local origin) by residents of different age categories have been assessed. The obtained results of assessing the levels of food consumption have been compared with our own results of earlier studies and with the results of studies on the population of Russia and Belarus. Similarly with previous years, among agricultural food products the most consumed products are milk and potatoes and among natural food products are mushrooms. The established levels of consumption of local dairy products and beef have decreased over the past ten years and the resident consumptions of mushrooms and potatoes are in the same levels as before.
Impact of mining and fuel and energy enterprises on the radiation background of territories
Authors: Perevoshchikov R. D. , Perevoshchikova A. A. , Menshikova E. A.
Published: December 2023

This review provides information on the radiation situation in mining and energy production facilities. Mining activities are considered as one of the significant sources of radioactivity. Many radionuclides and metals that are transported by surface and ground waters, air flows over significant distances, contaminating soils, subsoil and bottom sediments of the adjacent territory, forming geochemically specific naturaltechnogenic areas. In this work is given an overview of radiation conditions in the territories of potassium phosphate, hydrocarbon and coal deposits. Developed potassium ores are the source of 40K emission into the environment. According to the results obtained, the migration of investigated radionuclides is limited to the zone of 2 km. Only an insignificant part of the investigated samples (8%) exceeds the world average activity of 40K for soils. In bottom sediments, the average activity of 40K does not exceed the values for other territories with anthropogenic impact. More than 30 million tonnes of phosphate fertilizers are consumed worldwide each year, and their use increases crop production. However, a possible negative effect of these fertilisers is the contamination of cultivated land with some natural radionuclides. Uranium concentrations in phosphate vary from 37 to 4900 Bq/kg for 238U and from 100 to 10 000 Bq/kg for 226Ra. The amount of radioactivity in oil, gas and formation water is estimated through determination of 40K, 226Ra, 232Th. According to the published data, increased radiation background is observed near wellheads, in the places of oil sludge accumulation, near the flares at oil and gas enterprises, as a result of bringing a number of natural and man-made radionuclides (226Ra, 232Th, 40K, 137Cs, 90Sr, etc.) to the day surface. Coal mines are sources of radioactive contamination. This results from the extraction of large amounts of natural radionuclides from the subsoil together with the coal. This paper presents the average natural radionuclides content in coals from some of the world’s coal mines. With the development of mining and fuel-energy complexes, there is an active export to the surface together with minerals of natural radionuclides 40K, 232Th, 226Ra, 238U, which leads to an increase in the radiation load on the environment. In this connection, the problems of ensuring radiation safety at the facilities of mining and fuel and energy industry require the closest attention.
Lei de Anistia, ADPF 153 e julgamento do Caso Gomes Land e outros vs. Brasil
Authors: Barcellos Rafael Siegel , Quintanilha Neto Francisco Veras
Published: December 2023

O presente trabalho pretende investigar o alcance do conceito de justiça de transição no Brasil, a partir da análise do julgamento da ADPF nº 153 pelo Supremo Tribunal Federal e do caso Gomes Land e outros contra o Brasil na Corte Interamericana de Direito Humanos, e como os entendimentos consignados nessas ações repercutem na consolidação do regime democrático. Com efeito, a tradicional ideia de transição justa tem, como principal preocupação, evitar qualquer risco de retorno autoritário, deixando, pelo sucesso desse objetivo, pouco espaço para a reparação dos eventuais crimes perpetrados pelos agentes ditatoriais. É necessário, contudo, se perquirir se esse conceito de justiça de transição é suficiente para assegurar a estabilidade democrática ou se, ao contrário, a falta de punição às violações aos direitos humanos no decorrer de um governo autoritário faz surgir nos atores da repressão um sentimento de que a liberdade democrática e os direitos fundamentais são apenas concessões que poderão ser afastadas a qualquer momento. Para analisar a problematização proposta, será apreciado, primeiramente, o contexto histórico-político do período de redemocratização e do advento da Lei nº 6.683/1979. Na sequência, serão estudados o posicionamento do Supremo Tribunal Federal quanto à constitucionalidade da Lei de Anistia e o entendimento da Corte Interamericana de Direitos Humanos em relação a este mesmo ordenamento jurídico. Por fim, se abordará como a anistia aos agentes ditatoriais, que cometeram crimes contra os direitos humanos no decorrer do regime de exceção, pode ocasionar um enfraquecimento da democracia e a perpetuação da violação a direitos humanos. Neste panorama persegue-se a hipótese de que a ideia de justiça de transição como um acordo político que busca, precipuamente e quase que exclusivamente, evitar uma regressão autoritária, acaba por fomentar acordos precários que não se preocupam em reparar as eventuais violações a direitos perpetradas pelo regime de exceção e, por corolário, sustenta uma permanente ameaça tácita de retorno ditatorial, bem como, referenda a manutenção de práticas atentatórias aos direitos humanos.
Abençoado seja o Fruto: Um estudo sobre as violações aos direitos sexuais e reprodutivos das mulheres no livro “O Conto da Aia” e os reflexos no Brasil contemporâneo
Authors: Da Silva Henrique Mayla , Bruzaca Ruan Didier
Published: December 2023

O presente artigo tem o objetivo de analisar as violações aos direitos sexuais e reprodutivos das mulheres brasileiras, sob a perspectiva da obra distópica O Conto da Aia, com o propósito de observar semelhanças no método de violação a estes direitos. Para isso, foi feita uma análise da obra em questão, apresentando o contexto na qual se inserem tais violações e, em seguida, apresentado o histórico das políticas femininas e a forma pela qual os ideais patriarcais influenciaram em sua construção, demonstrando grande força nos direitos sexuais e reprodutivos. Diante disso, foi observado a semelhança nas violações a estes direitos, quando as políticas públicas são permeadas por um conservadorismo religioso. Como metodologia, foi escolhida a pesquisa bibliográfica, por meio da leitura da obra e de artigos, mídias digitais e legislações correspondentes, sendo possível observar as semelhanças existentes entre a obra ficcional e o Estado brasileiro.
Magnum Opus of Mohammed Arkoun; Cultural Resilience Amidst Pluralism
Authors: Utomo Sigit Tri , Marhumah Marhumah , Karwadi Karwadi , Suwandi Mohamad Ardin
Published: December 2023

The world faces a multidimensional crisis, with cultural, ethnic, racial, linguistic, and ethnic diversity giving rise to various issues. Wars in different parts of the world continue to result in bloody events and casualties. Preventive efforts are needed to address these problems, including promoting a culture of tolerance. Mohammed Arkoun was a figure and philosopher of pluralism who advocated and conveyed ideas about pluralism. The weaknesses of classical Islamic theological thinking become apparent when confronted with the empirical social reality of human life that continues to evolve with the advancement of science and technology. Mohammed Arkoun, an intellectual fNrom Algeria, attempted to comprehensively reinterpret the framework of Islamic thought, including aspects such as theology (kalam), Sufism, jurisprudence (fiqh), ethics, and exegesis (tafsir). Mohammed Arkoun expressed that Islam can succeed if Muslims adopt an open attitude toward pluralistic thinking, as during the early Islamic period and the Middle Ages. This pluralism can be realized if religious understanding is based on human values, allowing Muslims to interact with anyone. This research uses a qualitative method with a literature review study type, gathering data from various references, books, and articles related to Mohammed Arkoun's magnum opus: the study of cultural tolerance resilience amid pluralism. According to Arkoun, debates based on cultural diversity, thought, and theology in classical Islam lead to profound interpretations of the Quran and laws based on sacred texts.
Dynamics of MUI’s Fatwa on Zakat al-Fitr Paid in Qimah: Analysis of Guidelines for Issuing Fatwas
Authors: Mafaid Ahmad , Yuslem Nawir , Tanjung Dhiauddin
Published: December 2023

The MUI’s fatwa regarding zakat fitrah through qimah raises some dynamics and contradictions. The fatwa issued by the North Sumatra MUI in 2008, the Aceh MPU in 2014, and the DKI Jakarta MUI in 2018 have different decisions that give rise to contradictions at first glance. Through a literature study using the descriptive analytical method, this study aimed to unravel the dynamics of the fatwa of zakat al-fitr through bimah and analyze it based on the MUI fatwa stipulation guidelines. The results showed that the fatwa issued differed from the procedures for establishing a fatwa. In the MUI fatwa guidelines, it is stated that MUI and Regional MUI fatwa decisions, which are based on predetermined guidelines, have equal status and do not cancel each other, and if there are differences between MUI and Regional MUI fatwa decisions regarding the same issue, a meeting between the two leadership councils needs to be held to find the best solution. This study recommended that the Central MUI review the fatwa of zakat fitrah through bimah and guidelines for establishing fatwas.
Fabrication of porous carbon nanofiber webs from polyacrylonitrile and cellulose acetate for NaCl removal from water using capacitive deionization
Authors: Tarus Bethwel , Jande Yusufu , Njau Karoli
Published: December 2023

Capacitive deionization (CDI) has shown potential in addressing freshwater scarcity. CDI's electrode design is a key to better performance as it determines the extent of water purification. For carbon electrodes, the pore structure is an important factor influencing removal kinetics and ion storage. Herein, porous carbon nanofibers with diameters ranging from 277 to 348 nm were fabricated from blends of polyacrylonitrile (PAN) and cellulose acetate (CA) through electrospinning and carbonization. Surface area and pore properties were adjusted by varying the proportions of the precursors while ensuring no adverse alteration to the products' tangible properties. Enhanced pore structure and specific surface area were evident in the blend-based carbon nanofibers. The blend ratio of 2:8 (CA:PAN) had a high specific surface area of 925.47 m2/g and a pore volume of 0.7884 cm3/g. Correspondingly, a high specific capacitance of 177.5 F/g was attained. Desalination performance was determined in batch mode using 500 mg/L NaCl solution. A salt adsorption capacity of 6.57 mg/g and charge efficiency of 0.46 was obtained for the blend that had 20% CA. The carbon nanofibers demonstrated good desalination stability when used repetitively indicating their excellent potential for practical application.
Technical structure and influencing factors of nitrogen and phosphorus removal in constructed wetlands
Authors: Yang Lei , Jin Xiaohui , Hu Yawei , Zhang Mingqi , Wang Huihui , Jia Qian , Yang Yafei
Published: December 2023

Constructed wetlands purify water quality by synergistically removing nitrogen and phosphorus pollutants from water, among other pollutants such as organic matter through a physical, chemical, and biological composite remediation mechanism formed between plants, fillers, and microorganisms. Compared with large-scale centralized wastewater treatment systems with high cost and energy consumption, the construction and operation costs of artificial wetlands are relatively low, do not require large-scale equipment and high energy consumption treatment processes, and have the characteristics of green, environmental protection, and sustainability. Gradually, constructed wetlands are widely used to treat nitrogen and phosphorus substances in wastewater. Therefore, this article discusses in detail the role and interaction of the main technical structures (plants, microorganisms, and fillers) involved in nitrogen and phosphorus removal in constructed wetlands. At the same time, it analyses the impact of main environmental parameters (such as pH and temperature) and operating conditions (such as hydraulic load and hydraulic retention time, forced ventilation, influent carbon/nitrogen ratio, and feeding patterns) on nitrogen and phosphorus removal in wetland systems, and addresses the problems currently existing in relevant research, the future research directions are prospected in order to provide theoretical references for scholars’ research.
Investment Attractiveness and Grinium Effect of Green Securities of the Russian Banking Sector
Authors: Domaschenko D. V. , Anikin D. O.
Published: December 2023

One of the main ways for banks to implement activities within the ESG agenda is to issue green securities, the proceeds of which go to finance environmental projects. In turn, the nature of investments is reflected in the so-called discount on greenness or the greenium effect, which may scare away a potential investor. But the situation is different in the emerging green bond market in Russia. In this regard, an analysis of the main characteristics of green bonds of the Russian banking sector, as well as an assessment of their investment attractiveness in comparison with instruments of the classical type, offers an effective tool for the formation of long-term capital aimed at implementing the concept of sustainable development.
Consolidated Budgets of the Subjects of the Russian Federation in the First Half of 2023. Budget Risks are Increasing
Authors: Lykova L. N.
Published: December 2023

The performance of the consolidated budgets of the subjects of the Russian Federation in the first half of this year was characterized by real growth rates of income taxreceipts and only nominal growth personal income tax receipts.The increase in federal transfer receipts was partly determined by the financing of the budgets of the new regions of the Russian Federation. In addition to the growth of economic activity, the dynamics of own revenues of regional budgets in the first half of the year was influenced by factors such as the cancellation of income tax payments within consolidated groups of taxpayers and the accelerated procedure for personal income tax reimbursement.The growth of expenditures of regional budgets lagged behind the growth of revenues, but significantly outpaced last year’s figures, which resulted in a reduction in the surplus of subfederal budgets compared to the previous year. The trend towards an increase in the volume of state and municipal debt has continued against the background of an increase in debt to the Ministry of Finance of the Russian Federation. The growth of public debt is taking place both in relatively prosperous regions and in problematic ones. The reduction in the volume of debt obligations by individual subjects of the Russian Federation cannot yet change the overall picture. The approved law on the federal budget for 2024 and subsequent years assumes a reduction in federal support for regional budgets against the background of an increase in spending needs and contains significant risks for the execution of sub-federal budgets.
Epistemologia e educação
Authors: Battisti Fernando , Cerutti Elisabete
Published: December 2023

Este estudo tem por objetivo apresentar o conceito de Humanismo Digital, mediante a necessidade emergente de um sentido epistemológico para as práticas educativas no contexto das múltiplas relações humanas que possuem vivências com as tecnologias digitais. A proposta aprofunda o sentido de um Humanismo Digital, por meio da compreensão de um novo humanismo, da cibercultura e da complexidade das práticas educativas na relação entre o físico e o digital, no processo de ensino e de aprendizagem. O trabalho tem caráter qualitativo e hermenêutico, com uma compreensão dialética. Os caminhos da pesquisa dialogam, inicialmente, sobre o sentido da gnosiologia filosófica demonstrado pelas teorias do conhecimento ao longo do tempo, com ênfase da modernidade. Posteriormente, o entendimento da concepção de um novo humanismo contemporâneo nas relações sociais, em especial, no fazer pedagógico diante da cibercultura e da complexidade.
Aliansi Laki-laki Baru dan Upaya Meredefinisi Peran Gender melalui Kampanye #KitaMulaiSekarang
Authors: Abrianthy Elisabeth Garnistia , Syauki Wifka Rahma
Published: December 2023

Gender inequality has long been a central issue in global social discussions, and Indonesia is no exception. In many circumstances, working women are required to fulfill dual roles in society. On one hand, they are expected to contribute economically, but on the other, traditional expectations compel them to remain as household caretakers. This dual burden can be physically and mentally taxing. Fortunately, organizations like the New Men's Alliance are taking proactive steps to address this inequality. Through the #WeStartNow campaign, they aim to redefine gender roles in society, especially regarding domestic responsibilities. In this context, the research objective is to analyze how the New Men's Alliance, via their Instagram account @lakilakibaru, portrays and interprets gender equality. Specifically, the study focuses on how the visuals and narratives presented reflect the organization's views and aspirations concerning gender equality in Indonesia. The research method employed is Roland Barthes' semiotics, as it offers a deep analytical lens to comprehend the message conveyed by the #WeStartNow campaign. Based on the findings, the #WeStartNow campaign video depicts domestic work in a more positive light when performed by men. However, findings also suggest criticism that when men engage in domestic tasks, it seems more of a romantic gesture than a role-sharing with women, raising further questions about the campaign's effectiveness in genuinely raising awareness about gender equality
Fake Instagram: Manajemen Identitas Dan Privasi Melalui Fenomena Finstagram
Authors: Desideria Nathania , Syaki Wifka Rahma
Published: December 2023

With the surge in Instagram's popularity among Indonesian college students, a notable trend emerges where many manage a secondary account, commonly referred to as Finstagram (Fake Instagram). This distinct account serves as an outlet for them to candidly share stories from their daily lives, often with a more select audience. Recognizing the significance of this phenomenon, this research embarked on an exploration to fathom the depth of their privacy management on Finstagram. By harnessing the Communication Privacy Management theory, the study intended to dissect the underlying motivations and mechanisms that govern students' decisions on their digital privacy. Utilizing a qualitative methodology anchored in a phenomenological approach and a constructivist paradigm, the research delved into the lived experiences of these students. Data, rich in narratives, was gathered from meticulous in-depth interviews. Preliminary findings unveiled several pivotal privacy strategies. Students frequently adopted pseudonyms, consciously refrained from showcasing their faces in profile pictures, and judiciously harnessed the private account feature on Instagram. Interestingly, while they reserved highly personal information for a tight-knit circle labeled "close friends", instances of boundary turbulence were scarcely reported. Yet, the tug-of-war in privacy management, denoted as dialectics, was consistently evident.
Implementasi Kampanye Sosial Program Vaksinasi di Indonesia Sebagai Bentuk Pemulihan Pasca-Pandemi Covid-19
Authors: Hasna Sofia
Published: December 2023

The Pandemic Covid-19 in Indonesia continues with an increase in cases counting until January 28, 2021, there were 13,695 cases with a total of 1,037,993 cases of Covid-19 since it was first announced in early March 2020, therefore there is a need for post-pandemic-recovery-efforts-Covid-19-vaccination-program as a form of herd immunity carried out through campaigns on social media with the hashtag #VaksinCovid19. So that the communication element becomes very important in persuading the public to carry out a social campaign for the Covid-19 vaccination program as a form of post-pandemic recovery. This research aims to see how the implementation of post-pandemic Covid-19 recovery through a social campaign for the vaccination program. This research method uses descriptive qualitative with a literature study method that comes from secondary sources. The Result shows that the current government needs an appropriate communication strategy and target targets based on demographics to the psychology of the community, besides that, it also requires stakeholders to expand engagement in the social campaign for the Covid-19 vaccination program. Also, referring to secondary data with the Brand24 application to see the effectiveness of #VaksinCovid19 shows that the public perception of the Covid-19 vaccine program campaign is still classified as negative.
Evolutie van bacteriële kolonisatie en antibioticaresistentie in wonden bij gehospitaliseerde paarden: een retrospectieve studie
Authors: Volders A. , Haspeslagh M. , Van Hende D. , Martens A.
Published: December 2023

Wondinfecties zijn een belangrijke oorzaak van het vertraagd helen van wonden bij paarden. Deze studie had als doel na te gaan of er een verschil in prevalentie kan aangetoond worden in kiemen die een wondinfectie veroorzaken bij het paard en of er een evolutie kan aangetoond worden op het gebied van antibioticaresistentie. Hiervoor werden twee cohortes vergeleken: periode 1 (2009-2010) waarbij 35 stalen van geïnfecteerde wonden werden opgenomen en periode 2 (2019- 2020) waarbij 33 stalen werden opgenomen. Voor Pseudomonas spp. kon een significante daling in prevalentie aangetoond worden tussen periode 1 en periode 2 (P=0,035; OR=4,58). Voor de andere species kon er geen statistisch significant verschil aangetoond worden en kan er dus over het algemeen gesteld worden dat er weinig verandering is in welke kiemen een wondinfectie veroorzaken bij paarden. Wat antibioticumresistentie betreft werd een duidelijke evolutie tussen periode 1 en periode 2 waargenomen met een statistisch significante daling van de resistentie tegen aminoglycosiden (p < 0,001; OR = 7,68), gepotentialiseerde sulfonamiden (p < 0,01; OR = 4,92) en nitrofuranen (p < 0,03; OR = 2,62). Verder kon een significante daling in multiresistentie aangetoond worden (p < 0,01; OR = 3,15). De resultaten van dit onderzoek tonen aan dat verhoogde aandacht voor het voorzichtig omspringen met het antibioticumgebruik voor de wondbehandeling bij paarden loont.
Validasi Instrumen Supervisi Akademik Digital dalam Peningkatan Profesionalisme Guru Menggunakan Teknologi Digital
Authors: Nisa Kamilatun
Published: December 2023

Salah satu pendorong peningkatan keprofesionalan guru adalah supervisi akademik berbasis digital. Supervisi akademik untuk menggunakan teknologi digital dalam pendidikan secara efektif, bersamaan dengan kompetensi digital, menjadi sentral dan diakui sebagai elemen kunci untuk konstruksi pengetahuan pedagogis. Pengujian penelitian ini bertujuan untuk memvalidasi instrumen penelitian yang telah dibuat oleh peneliti untuk mengukur upaya supervisi akademik sekolah menggunakan teknologi digital. Butir instrumen berpondasi dan dikembangkan berdasarkan teori yang diusulkan oleh Sergiovani Starrat (1993) mengenai supervisi akademik. Pengumpulan data diambil dari 50 guru di sekolah Jawa Timur dan dianalisis menggunakan Exploratory Factor Analysis (EFA) dibantu software SPSS 26. Hasil analisis dihasilkan lima faktor yang terdiri dari model supervisi akademik digital yang berfokus pada integrasi teknologi. Faktor-faktor tersebut adalah: 1) Asesmen pra observasi; 2) Observasi; 3) Pemberian solusi; 4) Refleksi; dan 5) Tindak Lanjut. Hasil penelitian ini bertujuan untuk mendukung program supervisi sekolah untuk menggunakan teknologi dalam implementasinya. Instrumen ini juga dapat digunakan untuk mengukur perbedaan sebelum dan sesudah penemuan, seperti pembinaan profesional guru di sekolah
Fixed drug eruption caused by fluconazole
Authors: Myasnikova T. N. , Latysheva T. V. , Romanova T. S. , Smirnov V. V.
Published: December 2023

Objective: to characterize a group of patients with fixed drug erythema (FDE) caused by fluconazole to determine the sensitivity and specificity of the local provocative application test (LPAT) and to evaluate cross-allergenic reactivity with other antifungal drugs of the azole group.

Materials and methods: a prospective study was conducted in the period from 2012 to 2022. 347 patients with delayed drug hypersensitivity (DDH) were consulted, FDE could be suspected in 86 patients (24.8%), of which 23 patients were caused by fluconazole (26.8%). We included patients with suspected fluconazole FDE (n=23). LPAT with fluconazole was performed in 12 patients, drug provocation test (DPT) with ketoconazole – 17, DPT with itraconazole – 15, DPT with fluconazole – 1.

Results: the ratio of men and women was 1:6.3, the average age was 30.39±10.23 years. In 1 patient, the diagnosis of FDE caused by fluconazole was withdrawn. Number of reactions: 1 – in 2 patients (9.1%), more than one reaction – in 20 (90.9%). 4 patients (18.2%) had atopy. Sensitivity of LPAT for diagnosing DDH in FDE caused by fluconazole was 41.7%, specificity – 100%, false-negative rate – 58.3%, positive predictive value – 100%. DPT with ketoconazole, itraconazole was negative in 100% of cases.

Conclusions: the results obtained allow us to conclude that FDE caused by fluconazole in the vast majority of cases developed in women aged 19 to 30 years. Since patients with FDE caused by fluconazole tolerate ketoconazole and itraconazole well, it is highly likely that they can switch from fluconazole to one of these drugs. LPAT should be used for diagnosing FDE caused by fluconazole, since it was absolutely safe for the patient and allowed avoiding DPT in 42% of patients. Importantly that the timely and correct diagnosis in more than 90% of cases, it was possible to prevent the development of a repeated reaction to fluconazole.
B-2 lymphocytes and the balance of pro and anti-inflammatory cytokines in infectious and autoimmune phenotypes of common variable immune deficiency
Authors: Sizyakina L. P. , Andreeva I. I. , Kharitonova M. V.
Published: December 2023

Objective: comparative characteristics of the subpopulation composition of B- lymphocytes and the cytokine spectrum of peripheral blood in infectious and non-infectious manifestations of CVID.

Materials and methods: the results of observation of 10 people diagnosed with CVID have been presented. Six patients the clinical manifestation had an infectious phenotype of the disease of synopulmonary localization. Four patients were diagnosed with Crohn's disease, hemolytic anemia, and autoimmune hepatitis. The level of cytokines IL-4, IL-10, IL-17, TNF-α, IFN-γ in blood serum was determined by the ELISA, the phenotypic characteristic of B cells of peripheral blood cells was carried out by flow cytofluorimetry.

Results: the proportion of memory B cells in the healthy donors is 30% of all B-lymphocytes, on infectious manifestation of CVID – 12%, with autoimmune – 14%. The number of switched memory B-lymphocytes relative to the total pool of B-2 cells in infectious manifestation is greater (2.3%) than in autoimmune ones (1.4%). In patients with infectious manifestations the content of IFN-γ and TNF-α was increased inrelation to healthy donors of the comparison group, there were no differences in the serum amount of IL-17, with autoimmune manifestations, the content of all these cytokines was increased, IFN-γ and TNF-α being to a greater extent.

Conclusion: impaired formation of memory B-lymphocytes and cytokine dysregulation of immune processes are detected regardless of the variant of clinical manifestation of CVID. The nature and degree of changes differ depending on the clinical phenotype of the disease.
Clinical and immunological characteristics of patients with moderate COVID-19 with different lung lesion areas
Authors: Skripkina N. A. , Sizyakin D. V. , Antonova E. A.
Published: December 2023

Objective: to study the clinical and immunological parameters of patients with COVID-19 in moderate form with varying degrees of lung tissue damage.

Materials and methods: 80 patients hospitalized with a diagnosis of «COVID-19, moderate form; complication: bilateral polysegmental interstitial pneumonia» were examined. The difference in laboratory parameters (general clinical, biochemical and immunological) was evaluated depending on the degree of lung damage (up to 25 and up to 50%). Comparison group: 20 healthy volunteers.

Results: the differences between patients with different lung lesion areas consisted in higher levels of prognosis severity markers – CRP, LDH. In the immune status in the CT group 2, there was a decrease in CD3+ lymphocytes and their helper subpopulation, dysimmunoglobulinemia and a higher IL-6 content.

Conclusions: CT examination is of great importance for monitoring the progression of the disease. The smaller area of lung lesion reflects a lighter course of the disease, which does not exclude the need for dispensary observation and rehabilitation after discharge.
Features of cytokine production at the systemic and local level in patients of reproductive age with external genital endometriosis
Authors: Levkovich M. A. , Ermolova N. V. , Krukier I. I. , Avrutskaya V. V. , Petrov Yu. A. , Grigoryants A. A. , Zabayrachnaya A. V.
Published: December 2023

Objective: to establish the features of cytokine production in patients of reproductive age with external genital endometriosis at various stages of the disease.

Materials and methods: the study included 52 patients with external genital endometriosis (EGE). Group I consisted of 31 patients with stages I–II of EGE, group II — 21 patients with stages III–IV of the disease, control group — 20 women without endometriosis. Serum samples were obtained before anesthesia, and peritoneal fluid (PF) samples were obtained during endoscopic examination of patients. Determination of the content of cytokines in blood serum and peritoneal fluid was carried out by enzyme immunoassay using a multifunctional counter for enzyme immunoassays with Victor software (Finland). TNF-α, IL-10 — using reagents from BenderMed Systems (Austria). IL-13, IL-18 using reagents from Cloud-CloneCorp (USA) according to the manufacturer’s recommendations. Application software packages (Megastat and Statistica 10.0) were used to create a database and conduct statistical research. To determine statistical differences between groups, the Mann-Whitney test was used for independent groups and the Wilcoxon test for dependent groups. P values less than 0.05 were considered statistically significant. Data are presented as median and quartiles.

Results: at stages I–II of EGE, an increase in the level of TNF-α, IL-18 was detected in the blood serum and peritoneal fluid, which can stimulate proliferation, invasion of endometrial cells and neovascularization; stage III–IV of the disease was characterized by an increase in the level of TNF-α, IL-10, IL-13 in the peritoneal fluid, which promotes disease progression by evading ectopic endometrial cells from immune control.

Conclusion: the identified features of the production of pro- and anti-inflammatory cytokines at the systemic and local level at various stages of EGE confirm their importance in the development of the disease. Further research is needed to understand the mechanisms underlying the progression of NGE and to develop methods for early diagnosis.
Immunological and epidemiological effectiveness of tularemia vaccination in the Donbass region
Authors: Trunova O. A. , Skrypka L. V. , Bagriy A. E. , Prochorov E. V. , Reznichenko N. A.
Published: December 2023

Objective: to evaluate the epidemiological and immunological efficacy of tularemia vaccination in the Donbass region from 1991 to the present.

Materials and methods: data on the incidence of tularemia, immunization coverage of the population, results of intradermal tests with tularin, agglutination reaction and indirect hemagglutination reaction with tularemia antigen were analyzed.

Results: since 2012, immunization against tularemia has not been carried out on the territory of the republic. Since 2015, this approach has resulted in the emergence of foci with multiple cases of human tularemia. Cases were registered on the territory of natural foci of Novoazovsky and Yasinovatsky districts. Since 2017, immunization of the population in enzootic territories has been resumed, planning and selection of contingents to be vaccinated was carried out in a differentiated manner. According to epidemic indications, 400 people were vaccinated from among those at risk of contracting tularemia. In 2020– 2022 vaccination was not carried out. In the five months of 2023, 520 people were vaccinated against tularemia, 80 people were revaccinated.

Conclusions: the use of tularemia vaccine in the Donetsk region for 70 years led to the containment of tularemia, demonstrating the epidemiological and immunological effectiveness of specific immunoprophylaxis. The armed conflict and the cessation of vaccination led to an increase in the activity of the epidemic process in natural foci among animals and a significant increase in the incidence of tularemia in humans.
Results of ligation the internal iliac and ovarian arteries in the experiment
Authors: Kantsurova M. R. , Rymashevsky A. N. , Voloshin V. V. , Sapronova N. G. , Todorov S. S. , Rymashevsky M. A. , Kantsurov R. N.
Published: December 2023

Objective: to study in an experiment on animals pathomorphological changes in the tissues of the uterus, appendages and blood vessels after ligation of the internal iliac and ovarian arteries.

Materials and methods: An experiment was conducted with 6 mature pigs. Group I (n=3) consisted of intact pigs without surgery, group II (n=3) included animals with ligation of the internal iliac and ovarian arteries on both sides. 12 months after the operation, slaughter was performed and the organo-complex of the uterus with appendages and iliac vessels was taken for electron microscopic pathomorphological examination.

Results: comparative results of the study of the uterus, appendages found that the normal structure of the mature uterus was preserved, there were no changes in the structure of the fallopian tubes, tissues and vessels of the ovaries. All changes were found in the area of ligation of the ovarian and internal iliac arteries, although the arteries retained their lumen, but were deformed and surrounded by dense fibrous connective tissue. Conclusion: ligation of the ovarian and internal iliac arteries with absorbable suture material causes only local changes. The sufficiency of collateral blood flow is confirmed by the absence of atrophy of the uterus, fallopian tubes and ovaries, as well as organ deformities.
10 Myths about Psychosomatics
Authors: Soldatkin V. A. , Soldatkina S. V.
Published: December 2023

This article is devoted to the actual problems of psychosomatic medicine. Common myths are discussed, according to which only 7 psychosomatic diseases are known (restrictive interpretation), or alternatively, all human diseases are psychosomatic (expansive interpretation). The article presents a modern classification of psychosomatic disorders, information on predisposition to them, and highlights the main concepts of pathogenesis. Attention is devoted to the main forms of somatoform disorders, organic neuroses, nosogenic disorders, and the problem of hypochondria is illuminated. In this article attention is paid to the need for an integrated approach to the treatment of psychosomatic disorders, including the impact on both mental and somatic components. The requirements for the use of psychopharmacological drugs in psychosomatic medicine are given, emphasis is placed on the principle of «minimum sufficiency», which requires the use of minor doses of safe drugs that can cure the psychosomatic symptoms and are capable to treat the diagnosed mental disorders. The main non-drug methods aimed at correcting psychosomatic disorders are presented. The authors are convinced that in the field of psychosomatics the chances for successful diagnosis and therapy are given by the concept of «counter movement» – the interdisciplinary interaction of psychiatrists and internists, the essence of which is the urgent need for interdisciplinary cooperation of psychiatrists and internists, which increases the chances of successful assistance in such a complex and myth-rich field like psychosomatics.
Introduction: Russo-European Artistic Encounters in the Eighteenth Century
Authors: Samu Margaret
Published: December 2023

Introduction: Russo-European Artistic Encounters in the Eighteenth Century
Andrei Matveev: Painting Allegory from Antwerp to Russia
Authors: Samu Margaret
Published: December 2023

In 1725, artist Andrei Matveev sent his Allegory of Painting to Catherine I from Antwerp, where Peter the Great had sent him to study. Matveev’s Allegory remains the earliest known easel painting on an allegorical subject by a Russian painter. This article examines the circumstances surrounding the painting’s creation in Antwerp and explores its iconography and sources. It then considers the place of Matveev’s work amid the allegorical imagery produced in early eighteenth-century Russia. This study offers a possible new interpretation of the painting and sheds light on the role Antwerp and its artistic legacy played in fostering Russia’s emerging artistic culture.
Ivan Argunov’s Portrait of Anna Kalmykova
Authors: Helprin Alexandra
Published: December 2023

This article examines Ivan Petrovich Argunov’s 1767 painting of Anna Nikolaevna Kalmykova, one of many Kalmyk children removed from their families by the Russian military and forcibly adopted by elite Russians and Europeans. Both sitter and painter were, in different ways, unfree: Argunov was enserfed by the Sheremetev family and Kalmykova was their ward. Examining the portrait’s many visual antecedents and references, this paper argues that Argunov used the intimate, informal styles of Enlightenment portraiture in a way that enmeshed its subject and author in the harsh social hierarchies of the Sheremetev household and imperial society. The relatively loose facture of the painting and its attention to the sitter’s liveliness and youth demonstrate Argunov’s skill as a modern portraitist. But although Kalmykova dominates the composition of her own portrait (which makes it unlike most other portraits of Kalmyk people in Russia during this period), Argunov makes clear that she is subordinate to her patron and other members of her “adoptive” family. Mapping the power structures of the household that enserfed him, Argunov combined private and ceremonial idioms in a way that said much about Kalmykova’s status and his own – a manner of portraiture that could only be copied by other artists from outside the household.
Translation as Politics: Translating Nikolai Karamzin’s Letters of a Russian Traveler in Nineteenth-Century France
Authors: Baudin Rodolphe
Published: December 2023

This article examines the three translations of Nikolai Karamzin’s Letters of a Russian Traveler published in nineteenth-century France. Relying on Descriptive Translation Studies so as to challenge the traditional narrative about the political innocuousness of Karamzin’s travelogue, it reconstructs the historical contexts of the three publications in order to highlight the political agendas of their translators and/or translating patrons. Far from being the innocent product of the translators’ sheer curiosity, the three translations prove to be political objects, used at three key moments in the history of Franco-Russian relations in the nineteenth century, in order to call for political change, to try and restore Russia’s damaged reputation, or to attempt to forge new diplomatic alliances.
Increasing Older Adults’ Social Connectedness: Development and Implementation of a Web-Assisted Acceptance and Commitment Therapy–Based Intervention
Authors: Zarling Amie , Kim Joseph , Russell Daniel , Cutrona Carolyn
Published: December 2023

In this article, we will provide a rationale for a web-assisted acceptance and commitment therapy (ACT) approach to loneliness among older adults, drawing upon theories from the literature on adult development and aging, emotion regulation, and loneliness. The intervention program was developed using the principles of ACT, which is a cognitive behavioral approach and unified model of human behavior change and psychological growth. The ACT intervention focuses on developing nonjudgmental present-focused awareness of internal experiences (thoughts, emotions, and memories) through strategies such as acceptance and mindfulness rather than directly modifying or removing them per se. The ACT intervention appears well-suited to assist older adults in coping with the challenges of aging, as the focus is on an individual’s willingness to sit with internal experiences out of one’s control (ie, acceptance), stepping back from negative or critical thoughts and developing greater kindness toward oneself (ie, defusion), discerning what is most important to one’s true self (ie, values), and building larger patterns of effective action based on such values (ie, committed action). The ACT intervention was developed as a resource for older adults who are socially isolated or having difficulty with social connectedness. Eight modules comprise the web-assisted ACT intervention program, which includes reading materials, video clips, and activities. Each module is followed by a summary, a homework assignment, a short quiz to assess learning, and a moderated discussion with a coach. The intervention program begins with reconnecting participants with their values. The goal of the ACT intervention program is to foster flexibility in a participant’s behavior so they can behave consistently with their chosen values, rather than becoming locked into a pattern of behavior that is driven by avoiding distress or discomfort. The ACT intervention approach is both novel and innovative, as it is based on ACT and leverages a behavioral health web platform that is flexible and inclusive in its design. The ACT intervention aims to help older adults become more socially connected, less lonely, and more satisfied with their relationships with other people. The emphasis that ACT places on values and living life in accordance with one’s values renders it an approach ideally suited to older adults. Finally, recommendations for future research regarding this approach to addressing loneliness among older adults is addressed.