bluuebunny/crossref_metadata_2025 huggingface dataset:
Mathematical Analysis of the Electromotive Induced Force in a Magnetically Damped Suspension
Authors: Aberturas Susana , Aguilera Juan Diego , Olazagoitia José Luis , García Miguel Ángel , Hernando Antonio
Published: March 2024

This study explores the advanced mathematical modeling of electromagnetic energy harvesting in vehicle suspension systems, addressing the pressing need for sustainable transportation and improved energy efficiency. We focus on the complex challenge posed by the non-linear behavior of magnetic flux in relation to displacement, a critical aspect often overlooked in conventional approaches. Utilizing Taylor expansion and Fourier analysis, we dissect the intricate relationship between oscillation and electromagnetic damping, crucial for optimizing energy recovery. Our rigorous mathematical methodology enables the precise calculation of the average power per cycle and unit mass, providing a robust metric for evaluating the effectiveness of energy harvesting. Further, the study extends to the practical application in a combined system of passive and electromagnetic suspension, demonstrating the real-world viability of our theoretical findings. This research not only offers a comprehensive solution for enhancing vehicle efficiency through advanced suspension systems but also sets a precedent for the integration of complex mathematical techniques in solving real-world engineering challenges, contributing significantly to the future of energy-efficient automotive technologies. The cases reviewed in this article and listed as references are those commonly found in the literature.
The Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism
Authors: Bourne Yves , Sulzenbacher Gerlind , Chabaud Laurent , Aráoz Rómulo , Radić Zoran , Conrod Sandrine , Taylor Palmer , Guillou Catherine , Molgó Jordi , Marchot Pascale
Published: March 2024

Macrocyclic imine phycotoxins are an emerging class of chemical compounds associated with harmful algal blooms and shellfish toxicity. Earlier binding and electrophysiology experiments on nAChR subtypes and their soluble AChBP surrogates evidenced common trends for substantial antagonism, binding affinities, and receptor-subtype selectivity. Earlier, complementary crystal structures of AChBP complexes showed that common determinants within the binding nest at each subunit interface confer high-affinity toxin binding, while distinctive determinants from the flexible loop C, and either capping the nest or extending toward peripheral subsites, dictate broad versus narrow receptor subtype selectivity. From these data, small spiroimine enantiomers mimicking the functional core motif of phycotoxins were chemically synthesized and characterized. Voltage-clamp analyses involving three nAChR subtypes revealed preserved antagonism for both enantiomers, despite lower subtype specificity and binding affinities associated with faster reversibility compared with their macrocyclic relatives. Binding and structural analyses involving two AChBPs pointed to modest affinities and positional variability of the spiroimines, along with a range of AChBP loop-C conformations denoting a prevalence of antagonistic properties. These data highlight the major contribution of the spiroimine core to binding within the nAChR nest and confirm the need for an extended interaction network as established by the macrocyclic toxins to define high affinities and marked subtype specificity. This study identifies a minimal set of functional pharmacophores and binding determinants as templates for designing new antagonists targeting disease-associated nAChR subtypes.
Anatomic versus Low Tibial Tunnel in Double-Bundle Posterior Cruciate Ligament Reconstruction: Clinical and Radiologic Outcomes with a Minimum 2-Year Follow-Up
Authors: Chen Chung-Yu , Hsu Chen-Heng , Chen Poyu , Hsu Kuo-Yao , Yang Cheng-Pang , Sheu Huan , Chang Shih-Sheng , Chiu Chih-Hao
Published: March 2024

There is currently no consensus on the optimal placement of the tibial tunnel for double-bundle posterior cruciate ligament (PCL) reconstruction. The purpose of this study was to compare the clinical and radiologic outcomes of double-bundle PCL reconstruction utilizing anatomic versus low tibial tunnels. We conducted a retrospective cohort study involving patients who underwent double-bundle PCL reconstruction between Jan 2019 and Jan 2022, with a minimum follow-up of 2 years (n = 36). Based on the tibial tunnel position on postoperative computed tomography, patients were categorized into two groups: anatomic placement (group A; n = 18) and low tunnel placement (group L; n = 18). We compared the range of motion, stability test, complications, and side-to-side differences in tibial posterior translation using kneeling stress radiography between the two groups. There were no significant differences between the groups regarding clinical outcomes or complication rates. No significant differences in the posterior drawer test and side-to-side difference on kneeling stress radiography (2.5 ± 1.2 mm in group A vs. 3.7 ± 2.0 mm in group L; p = 0.346). In conclusion, the main findings of this study indicate that both anatomic tunnel and low tibial tunnel placements in double-bundle PCL reconstruction demonstrated comparable and satisfactory clinical and radiologic outcomes, with similar overall complication rates at the 2-year follow-up.
Carbon Dioxide Pressure and Catalyst Quantity Dependencies in Artificial Photosynthesis of Hydrocarbon Chains on Nanostructured Co/CoO Surfaces
Authors: Kan Zhe , Wang Zibo , Ren Haizhou , Shen Mengyan
Published: March 2024

In this study, we investigated the influence of pressure and the quantity of Co/CoO catalyst on an artificial photosynthesis process that converts CO2 and H2O into hydrocarbons (CnH2n+2, where n ≤ 18). The adsorption of CO2 and H2O on Co/CoO surfaces proved to be pivotal in this photo-catalytic reaction. Photoexcited carbon dioxide and water molecules ((CO2)* and (H2O)*) generated by illuminating the catalyst surface led to the formation of alkene hydrocarbon molecules with carbon numbers following an approximate Poisson distribution. The optimal pressure was found to be 0.40 MPa. Pressure less than 0.40 MPa resulted in low CO2 adsorption, impeding excitation for photosynthesis. At greater pressure, oil/wax accumulation on Co/CoO surfaces hindered CO2 adsorption, limiting further photosynthesis reactions. The average number of carbon atoms in the hydrocarbons and hydrocarbon yield were correlated. The amount of Co/CoO was also found to affect the hydrocarbon yield. Our study contributes to the understanding of Co/CoO-catalyzed photosynthesis and suggests that an open-flow system could potentially enhance the productivity of long-chain hydrocarbons.
Discovery of Acyl-Surugamide A2 from Marine Streptomyces albidoflavus RKJM-0023—A New Cyclic Nonribosomal Peptide Containing an N-ε-acetyl-L-lysine Residue
Authors: Maw Zacharie A. , Haltli Bradley , Guo Jason J. , Baldisseri Donna M. , Cartmell Christopher , Kerr Russell G.
Published: March 2024

We report the discovery of a novel cyclic nonribosomal peptide (NRP), acyl-surugamide A2, from a marine-derived Streptomyces albidoflavus RKJM-0023 (CP133227). The structure of acyl-surugamide A2 was elucidated using a combination of NMR spectroscopy, MS2 fragmentation analysis, and comparative analysis of the sur biosynthetic gene cluster. Acyl-surugamide A2 contains all eight core amino acids of surugamide A, with a modified N-ε-acetyl-L-lysine residue. Our study highlights the potential of marine Streptomyces strains to produce novel natural products with potential therapeutic applications. The structure of cyclic peptides can be solved using MS2 spectra and analysis of their biosynthetic gene clusters.
An Evaluation of the Edible Value of Salvia miltiorrhiza Seeds: Proximate Composition, Phytochemical Components and Antioxidant Activity
Authors: Deng Ruixue , Ren Xueli , Liu Dongjie , Lu Zongyuan , Liu Pu
Published: March 2024

Salvia miltiorrhiza seeds (SMS) are the main by-product of the production processing of Radix Salviae Miltiorrhizae. The main purposes of this work are to analyse the nutritional components in SMS, to explore the antioxidant activity of the chemical components in SMS and to evaluate the possibility of SMS as a raw material for functional foods. The contents of crude fibre, total protein, carbohydrates, total phenolics and flavonoids in SMS and the composition and relative content of fatty acids in SMS oil were determined. The results suggested that SMS has high contents of crude fibre (28.68 ± 4.66 g/100 g), total protein (26.65 ± 2.51 g/100 g), total phenolics (6.45 ± 0.55 mg of gallic acid equivalent/g) and total flavonoids (3.28 ± 0.34 mg of rutin equivalent/g), as well as a high level of α-linolenic acid (33.774 ± 4.68%) in their oil. Twenty-two secondary metabolites were identified in SMS residue, and nine compounds were isolated. The IC50 values of the total phenolic content in SMS on an ABTS radical, DPPH radical, superoxide radical and hydroxyl radical were 30.94 ± 3.68 μg/mL, 34.93 ± 4.12 μg/mL, 150.87 ± 17.64 μg/mL and 230.19 ± 24.47 μg/mL, respectively. The results indicate that SMS contain many nutrients and have high utilization value as a promising functional food.
The Neglected Role of Asphaltene in the Synthesis of Mesophase Pitch
Authors: Wang Mingzhi , Li Yulin , Wang Haoyu , Tao Junjie , Li Mingzhe , Shi Yuzhu , Zhou Xiaolong
Published: March 2024

This study investigates the synthesis of mesophase pitch using low-cost fluid catalytic cracking (FCC) slurry and waste fluid asphaltene (WFA) as raw materials through the co-carbonization method. The resulting mesophase pitch product and its formation mechanism were thoroughly analyzed. Various characterization techniques, including polarizing microscopy, softening point measurement, Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA), were employed to characterize and analyze the properties and structure of the mesophase pitch. The experimental results demonstrate that the optimal optical texture of the mesophase product is achieved under specific reaction conditions, including a temperature of 420 °C, pressure of 1 MPa, reaction time of 6 h, and the addition of 2% asphaltene. It was observed that a small amount of asphaltene contributes to the formation of mesophase pitch spheres, facilitating the development of the mesophase. However, excessive content of asphaltene may cover the surface of the mesophase spheres, impeding the contact between them and consequently compromising the optical texture of the mesophase pitch product. Furthermore, the inclusion of asphaltene promotes polymerization reactions in the system, leading to an increase in the average molecular weight of the mesophase pitch. Notably, when the amount of asphaltene added is 2%, the mesophase pitch demonstrates the lowest ID/IG value, indicating superior molecular orientation and larger graphite-like microcrystals. Additionally, researchers found that at this asphaltene concentration, the mesophase pitch exhibits the highest degree of order, as evidenced by the maximum diffraction angle (2θ) and stacking height (Lc) values, and the minimum d002 value. Moreover, the addition of asphaltene enhances the yield and aromaticity of the mesophase pitch and significantly improves the thermal stability of the resulting product.
The Nascent State
Authors: Ferreira Filipe
Published: March 2024

I suggest here ecologies of the nascent state, posing the following general questions: what is this state and what is it to live, to fabricate modes of life, in its immanence? I believe populating this state is, by right, ‘ecological’, even if what I offer here is only a sketch or glimpse, playful as it is, of the possibility of such modes of life, of dwelling. As I develop it here, the nascent is in flight of being. It is populated by lesser, minoritarian existences. If it is ‘ecological’, it is because these existences, or modes of becoming, are themselves, in their own right, ‘ecologies’, that is, modes of dwelling, of life, on the ‘other side of existence’, as Antonin Artaud put it once, in exile from Being. The power to return eternally to the nascent state is the power to live, to dwell, in the absolute forgetfulness of Being, in the interstice where philosophy supposedly ends, but where it nevertheless begins again, in oblivion itself, where being is never already the verticality of Being, its difference with beings, but always nascent, in the beginning, eternally so.
Amnion Rupture Sequence
Authors: Gică Nicolae , Nedelea Florina Mihaela , Apostol Livia Mihaela , Panaitescu Anca Maria , Huluță Iulia , Vayna Ana Maria , Botezatu Radu , Gana Nicoleta
Published: March 2024

The amnion rupture sequence is a rare condition occurring early in pregnancy, resulting in complex fetal anomalies by disrupting normal embryonic development. The prevalence of amnion rupture sequence is reported to be 1.16 in 10,000 live births. This article explores the uncommon case of early amnion rupture leading to fetal encephalocele, suspected in the first trimester. Despite the variable and intricate nature of anomalies associated with this condition, cranio-facial and abdominal defects are frequently observed. Genetic testing was conducted, with normal results supporting our theory of amnion rupture. The patient decided to terminate the pregnancy, and the anatomopathological results confirmed the findings. This article discusses the diagnostic challenges, emphasizing the importance of timely identification through advanced imaging techniques.
Correction: Gao et al. A Modeling Method for Thermal Error Prediction of CNC Machine Equipment Based on Sparrow Search Algorithm and Long Short-Term Memory Neural Network. Sensors 2023, 23, 3600
Authors: Gao Ying , Xia Xiaojun , Guo Yinrui
Published: March 2024

In the original publication [...]
Research on Fault Prediction Method of Elevator Door System Based on Transfer Learning
Authors: Pan Jun , Shao Changxu , Dai Yuefang , Wei Yimin , Chen Wenhua , Lin Zheng
Published: March 2024

The elevator door system plays a crucial role in ensuring elevator safety. Fault prediction is an invaluable tool for accident prevention. By analyzing the sound signals generated during operation, such as component wear and tear, the fault of the system can be accurately determined. This study proposes a GNN-LSTM-BDANN deep learning model to account for variations in elevator operating environments and sound signal acquisition methods. The proposed model utilizes the historical sound data from other elevators to predict the remaining useful life (RUL) of the target elevator door system. Firstly, the opening and closing sounds of other elevators is collected, followed by the extraction of relevant sound signal characteristics including A-weighted sound pressure level, loudness, sharpness, and roughness. These features are then transformed into graph data with geometric structure representation. Subsequently, the Graph Neural Networks (GNN) and long short-term memory networks (LSTM) are employed to extract deeper features from the data. Finally, transfer learning based on the improved Bhattacharyya Distance domain adversarial neural network (BDANN) is utilized to transfer knowledge learned from historical sound data of other elevators to predict RUL for the target elevator door system effectively. Experimental results demonstrate that the proposed method can successfully predict potential failure timeframes for different elevator door systems.
Predictive Neural Network Modeling for Almond Harvest Dust Control
Authors: Serajian Reza , Sun Jian-Qiao , Cobian-Iñiguez Jeanette , Ehsani Reza
Published: March 2024

This study introduces a neural network-based approach to predict dust emissions, specifically PM2.5 particles, during almond harvesting in California. Using a feedforward neural network (FNN), this research predicted PM2.5 emissions by analyzing key operational parameters of an advanced almond harvester. Preprocessing steps like outlier removal and normalization were employed to refine the dataset for training. The network’s architecture was designed with two hidden layers and optimized using tanh activation and MSE loss functions through the Adam algorithm, striking a balance between model complexity and predictive accuracy. The model was trained on extensive field data from an almond pickup system, including variables like brush speed, angular velocity, and harvester forward speed. The results demonstrate a notable predictive accuracy of the FNN model, with a mean squared error (MSE) of 0.02 and a mean absolute error (MAE) of 0.01, indicating high precision in forecasting PM2.5 levels. By integrating machine learning with agricultural practices, this research provides a significant tool for environmental management in almond production, offering a method to reduce harmful emissions while maintaining operational efficiency. This model presents a solution for the almond industry and sets a precedent for applying predictive analytics in sustainable agriculture.
Liquid-Driven Microinjection System for Precise Fundus Injection
Authors: Xu Shiyu , Hu Bo , Liu Rongxin , Zhao Xin , Sun Mingzhu
Published: March 2024

Microinjection is usually applied to the treatment of some retinal disorders, such as retinal vein cannulation and displaced submacular hemorrhage. Currently, the microinjection procedure is usually performed by using the viscous fluid control of a standard vitrectomy system, which applies a fixed air pressure through foot pedal activation. The injection process with the fixed pressure is uncontrollable and lacks feedback, the high flow rate of the injected drug may cause damage to the fundus tissue. In this paper, a liquid-driven microinjection system with a flow sensor is designed and developed specifically for fundus injection. In addition, a PID sliding mode control (SMC) method is proposed to achieve precise injection in the injection system. The experimental results of fundus simulation injection demonstrate that the microinjection system meets the requirements of fundus injection and reduces the impact of the injection process on the fundus tissue.
Energy-Efficient Neuromorphic Architectures for Nuclear Radiation Detection Applications
Authors: Canales-Verdial Jorge I. , Wagner Jamison R. , Schmucker Landon A. , Wetzel Mark , Proctor Philippe , Carson Merlin , Meng Jian , Withers Nathan J. , Harris Charles Thomas , Nogan John J. , Webb Denise B. , Hecht Adam A. , Teuscher Christof , Osiński Marek , Zarkesh-Ha Payman
Published: March 2024

A comprehensive analysis and simulation of two memristor-based neuromorphic architectures for nuclear radiation detection is presented. Both scalable architectures retrofit a locally competitive algorithm to solve overcomplete sparse approximation problems by harnessing memristor crossbar execution of vector–matrix multiplications. The proposed systems demonstrate excellent accuracy and throughput while consuming minimal energy for radionuclide detection. To ensure that the simulation results of our proposed hardware are realistic, the memristor parameters are chosen from our own fabricated memristor devices. Based on these results, we conclude that memristor-based computing is the preeminent technology for a radiation detection platform.
Synthesis and Sensing Response of Magnesium Antimoniate Oxide (MgSb2O6) in the Presence of Propane Atmospheres at Different Operating Voltages
Authors: Guillén-Bonilla Héctor , Guillén-Bonilla José Trinidad , Rodríguez-Betancourtt Verónica-María , Ramírez-Ortega Jorge Alberto , Morán Lázaro Juan Pablo , Guillén-Bonilla Alex
Published: March 2024

Nanoparticles of MgSb2O6 were synthesized using a microwave-assisted wet chemistry method, followed by calcination at 700 °C. Their ability to detect different concentrations of propane gas (C3H8) at various operating voltages was evaluated. The material’s crystalline phase was identified using X-ray powder diffraction (XRD). The morphology was analyzed by scanning electron microscopy (SEM), finding bar- and polyhedron-type geometries. Through transmission electron microscopy (TEM), we found particle sizes of 8.87–99.85 nm with an average of ~27.63 nm. Employing ultraviolet–visible (UV-Vis) spectroscopy, we found a band gap value of ~3.86 eV. Thick films made with MgSb2O6 powders were exposed to atmospheres containing 150, 300, 400, and 600 ppm of propane gas for dynamic testing. The time-dependent sensitivities were ~61.09, ~88.80, ~97.65, and ~112.81%. In addition, tests were carried out at different operating voltages (5–50 V), finding very short response and recovery times (~57.25 and ~18.45 s, respectively) at 50 V. The excellent dynamic response of the MgSb2O6 is attributed mainly to the synthesis method because it was possible to obtain nanometric-sized particles. Our results show that the trirutile-type oxide MgSb2O6 possesses the ability, efficiency, and thermal stability to be applied as a gas sensor for propane.
The Role of Trust, Respect, and Relationships in Maintaining Lived Experience and Indigenous Authority in Co-Designed Research with People Living with Disability
Authors: Kerr Sharon , Sackley Roslyn , Gilroy John , Parmenter Trevor , O’Brien Patricia
Published: March 2024

Co-design of research can evolve organically when the questions to be asked have their roots deep1 in the soil of partnerships based on trust, respect, and a common vision for equity and inclusion. White Questions—Black Answers, a PhD thesis research project focusing on the inclusion of Indigenous students with disability in the Australian Higher Education Sector, demonstrates this premise. Founded on Indigenous Standpoint Theory, the methodology of this research foregrounds the central role of Indigenous people with lived experience of disability—in the study design, its implementation, and in the validation of the results. This paper shares the conceptual framework and relationship hierarchy for the research, ensuring that the authority of those with lived experience was maintained and central to all research activities. It showcases a way forward for other fields of co-designed research, delivering both academic rigour and leadership by those with lived experience.
Chemical Organization Theory as a General Modeling Framework for Self-Sustaining Systems
Authors: Heylighen Francis , Beigi Shima , Veloz Tomas
Published: March 2024

This paper summarizes and reviews Chemical Organization Theory (COT), a formalism for the analysis of complex, self-organizing systems across multiple disciplines. Its elements are resources and reactions. A reaction maps a set of resources onto another set, thus representing an elementary process that transforms resources into new resources. Reaction networks self-organize into invariant subnetworks, called ‘organizations’, which are attractors of their dynamics. These are characterized by closure (no new resources are added) and self-maintenance (no existing resources are lost). Thus, they provide a simple model of autopoiesis: the organization persistently recreates its own components. The resilience of organizations in the face of perturbations depends on properties such as the size of their basin of attraction and the redundancy of their reaction pathways. Application domains of COT include the origin of life, systems biology, cognition, ecology, Gaia theory, sustainability, consciousness, and social systems.
School Teachers’ Perceptions of Adolescent Human Papillomavirus (HPV) Vaccination: A Systematic Review
Authors: Choi Jihye , Gabay Efrat K. , Cuccaro Paula M.
Published: March 2024

School nurses are uniquely positioned to educate students about immunizations, including human papillomavirus (HPV) vaccination, but schools are often without a nurse for different reasons. In lieu of nurses, teachers who closely interact with students and are traditionally well-trusted by parents may be able to communicate about HPV vaccination, alleviating parental vaccine hesitancy. This systematic review explores school teachers’ perspectives on adolescent HPV vaccination and factors influencing their willingness to make vaccine recommendations. We searched three databases with appropriate medical subject headings and keywords to identify relevant studies. We reviewed fifteen studies and provided an extensive summary and a comparison of the results across the studies. Teachers had low to moderate levels of HPV knowledge with low self-efficacy to counsel parents about the HPV vaccine and expressed concerns about the vaccine condoning adolescent sexual activity, vaccine side effects, and parental disapproval. Nonetheless, some teachers showed interest in learning about vaccine effectiveness in preventing HPV-associated cancers and wanted guidance on vaccine communication with parents, viewing schools as adequate venues to promote and deliver HPV vaccines. Schools should consider educating teachers on HPV and HPV vaccination, with a focus on effective vaccine communication practices to increase adolescent HPV vaccine uptake.
Immunogenicity of Hepatitis B Vaccination in Patients with Ulcerative Colitis on Infliximab Is Attenuated Compared to Those on 5-Aminosalicylic Acid Therapies: A Prospective Observational Study
Authors: Shehab Mohammad , Alrashed Fatema , Alyaseen Munerah , Safar Zainab , Adekunle Tunrayo , Alfadhli Ahmad , Bessissow Talat
Published: March 2024

Introduction: Hepatitis B virus (HBV) infection has been associated with chronic hepatitis and cirrhosis. Patients with inflammatory bowel disease (IBD) may be at a higher risk of HBV infection reactivation, especially those on biologic therapies. This study intends to compare the effectiveness of the HBV vaccine in patients with ulcerative colitis (UC) on infliximab (IFX) compared to those on 5-aminosalicylic acid (5-ASA). Methods: Patients with UC aged >18 years old were prospectively enrolled in the study. The patients were divided into two groups: patients treated with 5-ASA (control group) and patients treated with IFX (study group). HBV vaccination was administered (20 mcg) following the standard regimen, and Hepatitis B serum antibody (HbsAb) titers were assessed three months after the final dose. The response to HBV vaccines was categorized as an ‘adequate’ immune response (≥10 IU/L) and ‘effective’ immune response (≥100 IU/L). Results: In our final analysis of 118 patients with UC, 54.2% were male and 52.5% had extensive colitis. HBsAb titer levels were significantly higher in the 5-ASA group (126.7 ± 37.5) compared to the IFX group (55.5 ± 29.4). Stratifying HBsAb levels into two categories (≥10–99 IU/L and ≥100 IU/L) revealed a significantly greater proportion of subjects in the 5-ASA group with levels ≥100 IU/L compared to the IFX group (76.7% vs. 12.1%, p < 0.001). Logistic regression analysis demonstrated that patients with UC receiving 5-ASA were 23.94 times more likely to exhibit HBsAb levels ≥ 100 compared to those treated with IFX (OR = 23.94, 95% CI 8.89–64.49). Conclusion: The immune response to hepatitis B vaccination in patients with ulcerative colitis treated with IFX is attenuated compared to those treated with 5-ASA. Therefore, emphasizing the importance of HBV vaccination for patients with IBD before starting anti-TNF therapy, especially IFX, and advocating for screening is imperative in high-risk countries. Determining what levels of HBsAb provide protection and what happens to the levels over time after a booster dose are important clinical questions to be answered by follow-up studies.
Research Progress and Prospects of Transit Priority Signal Intersection Control Considering Carbon Emissions in a Connected Vehicle Environment
Authors: Chen Xinghui , Hu Xinghua , Wang Ran , Zhao Jiahao
Published: March 2024

Transit priority control is not only an important means for improving the operating speed and reliability of public transport systems, but it is also a key measure for promoting green and sustainable urban transportation development. A review of signal intersection transit priority control strategy in a connected vehicle environment is conducive to discovering important research results on transit priority control at home and abroad and will promote further developments in urban public transport. This study analyzed and reviewed signal intersection transit priority control at four levels: traffic control sub-area divisions, transit signal priority (TSP) strategy, speed guidance strategy, and the impacts of intersection signal control on carbon emissions. In summary, the findings were the following: (1) In traffic control sub-area divisions, the existing methods were mainly based on the similarity of traffic characteristics and used clustering or search methods to divide the intersections with high similarity into the same control sub-areas. (2) The existing studies on the TSP control strategy have mainly focused on transit priority control based on fixed phase sequences or phase combinations under the condition of exclusive bus lanes. (3) Studies on speed guidance strategy were mainly based on using constant bus speeds to predict bus arrival times at intersection stop lines, and it was common to guide only based on bus speed. (4) The carbon emissions model for vehicles within the intersection mainly considered two types of vehicles, namely, fuel vehicles and pure electric vehicles. Finally, by analyzing deficiencies in the existing studies, future development directions for transit priority control are proposed.
TEMPE KATSU DAPAT MENINGKATKAN KADAR HEMOGLOBIN PADA REMAJA PUTRI
Authors: Rahmania Rizqi , Gumilar Mulus , Pusparini Pusparini , Priawantiputri Witri , Rosmana Dadang
Published: March 2024

Remaja putri rentan mengalami anemia karena kebutuhan zat gizinya meningkat akibat adanya menstruasi tiap bulan dan sedang dalam masa pertumbuhan. Kondisi ini dapat diperparah dengan pola makan remaja putri yang cenderung mengonsumsi jajanan kurang sehat dan bergizi. Tempe merupakan makanan sumber protein dan zat besi serta mengandung vitamin B6, folat, dan B12 yang dapat membantu pembentukan hemoglobin. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian tempe katsu terhadap asupan protein, asupan zat besi, dan kadar hemoglobin pada remaja putri di SMPN 1 Ciater. Desain penelitian quasy-experimental pre-post test with control group dengan jumlah sampel 14 orang per kelompok. Kelompok perlakuan diberi tempe katsu sebanyak 150 gram tiap seminggu dua kali selama 30 hari dan edukasi gizi, sedangkan kelompok kontrol hanya diberi edukasi gizi. Asupan protein dan zat besi didapat menggunakan SFFQ dan kadar hemoglobin diukur menggunakan EasyTouch GCHb. Hasil uji dependent t-test pada kelompok perlakuan untuk asupan protein 0,000; asupan zat besi 0,000; dan kadar hemoglobin 0,000. Hasil uji independent t-test antara kedua kelompok untuk asupan protein 0,002; asupan zat besi 0,000; dan kadar hemoglobin 0,094. Kesimpulan ada pengaruh pemberian tempe katsu terhadap peningkatan asupan protein, asupan zat besi, dan kadar hemoglobin. Ada perbedaan peningkatan asupan protein dan asupan zat besi, tetapi tidak ada perbedaan peningkatan kadar hemoglobin antara kedua kelompok. Rekomendasi penelitian selanjutnya menambah frekuensi pemberian produk dan menambah bahan makanan sumber zat gizi lain pada produk yang dapat meningkatkan efektivitas pembentukan hemoglobin.
ASUPAN ORAL INADEKUAT, PERUBAHAN NILAI LABORATORIUM, PERILAKU SALAH TENTANG MAKANAN PADA PASIEN CHRONIC KIDNEY DISEASE
Authors: Mahesa Dwipayani Ni Kadek , Fadhilah Zulfa Rizki , Isdiany Nitta
Published: March 2024

Latar Belakang : Chronic Kidney Disease (CKD) atau Penyakit Ginjal Kronik (PGK) adalah penyakit yang menyerang ginjal  dan kondisinya berangsur memburuk, menjadi kronis atau persisten dan berlangsung lama. Prevalensi kasus penyakit ginjal kronis di Indonesia menurut riset kesehatan dasar (Riskesdas) pada tahun 2018 adalah sebesar 0,38%. Hipertensi adalah salah satu faktor risiko yang sering ditemukan pada gagal ginjal. Peningkatan tekanan darah yang berlangsung lama pada arteriol dan glomeruli akan menyebabkan terjadinya sklerosis pada pembuluh darah. Kasus :  Tn.U berusia 50 tahun mengalami masalah gizi asupan oral inadekuat, perubahan nilai ureum dan kreatinin dan perilaku salah tentang makanan selama rawat inap diagnosis medis pasien adalah CKD dan Hipertensi. Hasil dan Pembahasan : Pemberian diet awal rendah protein 0,6 lalu pada akhir perawatan menjadi TETP on HD 1,2 gr/kg BBI dalam bentuk lunak disesuaikan dengan kemampuan daya terima pasien dilakukan agar terjadi peningkatan asupan pasien. Syarat diet yang diberikan pada awal intervensi adalah energi 2047,5 kkal, protein 35,1 gr, lemak 68,25 gr, karbohidrat 323,5 gr. Hasil monitoring dan evaluasi menunjukkan selama pengamatan di hari ketiga asupan energy pasien mencapai 75%. Hasil ureum dan kreatinin juga mengalami penurunan, fisik/klinis menunjukkan sesak berkurang namun masih mengalami mual pasca hemodialisa. Kolaborasi dilakukan bersama dengan DPJP, ahli gizi ruangan, perawat, dan pramusaji. Selama intervensi juga diiberikan edukasi dan konseling terkait pengaturan makan pasien. Simpulan : intervensi yang diberikan dapat mengatasi sebagian masalah gizi pasien.
Identifikasi Potensi Produk Pariwisata Sebagai Dasar Perencanaan Paket Wisata di Desa Cacaban Kidul Kabupaten Purworejo, Provinsi Jawa Tengah
Authors: Kurniati Cucu , Josary P. Jessica Jocelyn , Sinaga Endang Komesty , Puksi Faisal , Andrianto Ronal
Published: March 2024

Desa Cacaban Kidul which is located in the vicinity of the Borobudur Temple development area has potential in the tourism sector in three forms, including the form of natural tourism potential, cultural tourism, craft/creative tourism, as well as non-tourism potential such as agricultural and livestock product potential. This research hopes to be able to provide specific benefits for the welfare of the community through an effort to develop communitybased tourism through community empowerment in Desa Cacaban Kidul. In conducting the research, the potential of the tourism products and the components of tourism products in terms of attractions, amenities and accessibility in Desa Cacaban Kidul are identified and analyzed. The result of the study can serve as an opportunity for a creation of tour package as it serves some recommendation for Desa Cacaban Kidul so that they can be managed properly and optimally as an effort to develop sustainable tourism through a series of tourism activities packaged in a tour package.

Keywords: Tourism product, Tour Package Planning, Tourism Village
Analisis Aspek Manajemen Waktu pada Event Festival Bingen 2022 (Studi pada Divisi Logistik CV. Soundtrack Indonesia, Palembang)
Authors: Destia Ramdini  , Djohan Muhammad Iqbal , Wibowo Budi
Published: March 2024

In organizing an event there will be various divisions involved including the logistics division, one of the success factors of an event is the supply of goods from the logistics division, the logistics division will provide goods and distribute them to other divisions, the application of time management is one aspect that needs to be Paying attention to managing time properly will produce maximum results, so that the supply of goods by the logistics division will be more effective. This research discusses how the implementation of time management by the logistics division at the event Bingen Festival 2022. The research method used is qualitative research. Sources of research data conducted are from interviews and documentation. From the results of the study it was concluded that the logistics division has implemented several aspects of time management but there are still indicators that become notes for the logistics division that can be applied in the future.
Adaptive Gait Training of a Lower Limb Rehabilitation Robot Based on Human–Robot Interaction Force Measurement
Authors: Yu Fuyang , Liu Yu , Wu Zhengxing , Tan Min , Yu Junzhi
Published: March 2024

The existing fixed gait lower limb rehabilitation robots perform a predetermined walking trajectory for patients, ignoring their residual muscle strength. To enhance patient participation and safety in training, this paper aims to develop a lower limb rehabilitation robot with adaptive gait training capability relying on human–robot interaction force measurement. Firstly, a novel lower limb rehabilitation robot system with several active and passive driven joints is developed, and 2 face-to-face mounted cantilever beam force sensors are employed to measure the human–robot interaction forces. Secondly, a dynamic model of the rehabilitation training robot is constructed to estimate the driven forces of the human lower leg in a completely passive state. Thereafter, based on the theoretical moment from the dynamics and the actual joint interaction force collected by the sensors, an adaptive gait adjustment method is proposed to achieve the goal of adapting to the wearer’s movement intention. Finally, interactive experiments are carried out to validate the effectiveness of the developed rehabilitation training robot system. The proposed rehabilitation training robot system with adaptive gaits offers great potential for future high-quality rehabilitation training, e.g., improving participation and safety.
Enhancing Brain–Computer Interface Performance by Incorporating Brain-to-Brain Coupling
Authors: Jia Tianyu , Sun Jingyao , McGeady Ciarán , Ji Linhong , Li Chong
Published: March 2024

Human cooperation relies on key features of social interaction in order to reach desirable outcomes. Similarly, human–robot interaction may benefit from integration with human–human interaction factors. In this paper, we aim to investigate brain-to-brain coupling during motor imagery (MI)-based brain–computer interface (BCI) training using eye-contact and hand-touch interaction. Twelve pairs of friends (experimental group) and 10 pairs of strangers (control group) were recruited for MI-based BCI tests concurrent with electroencephalography (EEG) hyperscanning. Event-related desynchronization (ERD) was estimated to measure cortical activation, and interbrain functional connectivity was assessed using multilevel statistical analysis. Furthermore, we compared BCI classification performance under different social interaction conditions. In the experimental group, greater ERD was found around the contralateral sensorimotor cortex under social interaction conditions compared with MI without any social interaction. Notably, EEG channels with decreased power were mainly distributed around the frontal, central, and occipital regions. A significant increase in interbrain coupling was also found under social interaction conditions. BCI decoding accuracies were significantly improved in the eye contact condition and eye and hand contact condition compared with the no-interaction condition. However, for the strangers’ group, no positive effects were observed in comparisons of cortical activations between interaction and no-interaction conditions. These findings indicate that social interaction can improve the neural synchronization between familiar partners with enhanced brain activations and brain-to-brain coupling. This study may provide a novel method for enhancing MI-based BCI performance in conjunction with neural synchronization between users.
Diagnosing Overlapping and Differing Information for SPEAR and CFSv2 Global Precipitation Forecasts
Authors: Zhao Huiling , Zhao Tongtiegang
Published: March 2024

Global climate models (GCMs) provide valuable forecasts of precipitation around the world. This paper has presented an in-depth investigation of the overlapping versus differing information for 2 sets of GCM forecasts based on the classic set operations. Specifically, by using the coefficient of determination to measure the amount of information of precipitation observations contained in GCM forecast, the common part of the 2 sets of forecasts is quantified by the intersection operation and the unique part of 1 set of forecasts is quantified by the difference operation. A case study is devised for the global precipitation forecasts in December-January-February generated by the Seamless System for Prediction and EArth System Research (SPEAR) and the Climate Forecast System version 2 (CFSv2). Their overlapping and differing information are diagnosed. It is found that significant information common to the 2 sets of forecasts exists over 54.61% of global land grid cells, significant information unique to SPEAR forecasts over 23.59% of global land grid cells, and significant information unique to CFSv2 forecasts over 18.15% of global land grid cells. While the information unique to the SPEAR forecasts suggests that the SPEAR forecasts provide new information compared to the CFSv2 forecasts and the information unique to the CFSv2 forecasts suggests that the CFSv2 forecasts also provide new information compared to the SPEAR forecasts, the common information of the 2 sets of forecasts indicates that they present substantial amount of similar information. Overall, the diagnosis of the overlapping and differing information for different sets of GCM forecasts yields insights into GCM predictive performances.
Innovative Multivariable Model Combining MRI Radiomics and Plasma Indexes Predicts Alzheimer’s Disease Conversion: Evidence from a 2-Cohort Longitudinal Study
Authors: Yu Xianfeng , Sun Xiaoming , Wei Min , Deng Shuqing , Zhang Qi , Guo Tengfei , Shao Kai , Zhang Mingkai , Jiang Jiehui , Han Ying ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: March 2024

To explore the complementary relationship between magnetic resonance imaging (MRI) radiomic and plasma biomarkers in the early diagnosis and conversion prediction of Alzheimer’s disease (AD), our study aims to develop an innovative multivariable prediction model that integrates those two for predicting conversion results in AD. This longitudinal multicentric cohort study included 2 independent cohorts: the Sino Longitudinal Study on Cognitive Decline (SILCODE) project and the Alzheimer Disease Neuroimaging Initiative (ADNI). We collected comprehensive assessments, MRI, plasma samples, and amyloid positron emission tomography data. A multivariable logistic regression analysis was applied to combine plasma and MRI radiomics biomarkers and generate a new composite indicator. The optimal model’s performance and generalizability were assessed across populations in 2 cross-racial cohorts. A total of 897 subjects were included, including 635 from the SILCODE cohort (mean [SD] age, 64.93 [6.78] years; 343 [63%] female) and 262 from the ADNI cohort (mean [SD] age, 73.96 [7.06] years; 140 [53%] female). The area under the receiver operating characteristic curve of the optimal model was 0.9414 and 0.8979 in the training and validation dataset, respectively. A calibration analysis displayed excellent consistency between the prognosis and actual observation. The findings of the present study provide a valuable diagnostic tool for identifying at-risk individuals for AD and highlight the pivotal role of the radiomic biomarker. Importantly, built upon data-driven analyses commonly seen in previous radiomics studies, our research delves into AD pathology to further elucidate the underlying reasons behind the robust predictive performance of the MRI radiomic predictor.
Orexin Neurons to Sublaterodorsal Tegmental Nucleus Pathway Prevents Sleep Onset REM Sleep-Like Behavior by Relieving the REM Sleep Pressure
Authors: Feng Hui , Qiao Qi-Cheng , Luo Qi-Fa , Zhou Jun-Ying , Lei Fei , Chen Yao , Wen Si-Yi , Chen Wen-Hao , Pang Yu-Jie , Hu Zhi-An , Jiang Yi-Bin , Zhang Xu-Yang , Zhou Teng-Yuan , Zhang Xin-Yan , Yang Nian , Zhang Jun , Hu Rong
Published: March 2024

Proper timing of vigilance states serves fundamental brain functions. Although disturbance of sleep onset rapid eye movement (SOREM) sleep is frequently reported after orexin deficiency, their causal relationship still remains elusive. Here, we further study a specific subgroup of orexin neurons with convergent projection to the REM sleep promoting sublaterodorsal tegmental nucleus (OX
SLD
neurons). Intriguingly, although OX
SLD
and other projection-labeled orexin neurons exhibit similar activity dynamics during REM sleep, only the activation level of OX
SLD
neurons exhibits a significant positive correlation with the post-inter-REM sleep interval duration, revealing an essential role for the orexin-sublaterodorsal tegmental nucleus (SLD) neural pathway in relieving REM sleep pressure. Monosynaptic tracing reveals that multiple inputs may help shape this REM sleep-related dynamics of OX
SLD
neurons. Genetic ablation further shows that the homeostatic architecture of sleep/wakefulness cycles, especially avoidance of SOREM sleep-like transition, is dependent on this activity. A positive correlation between the SOREM sleep occurrence probability and depression states of narcoleptic patients further demonstrates the possible significance of the orexin-SLD pathway on REM sleep homeostasis.
Comparison of CO2 absorption via terrestrial plants and microalgae: A review
Authors: Erfianti Tia , Nurafifah Istini , Sadewo Brilian Ryan , Daryono Budi Setiadi , Suyono Eko Agus , Budiman Arief
Published: March 2024

Currently, global warming and climate change continue to increase along with CO2 gas emissions. This has an impact on the survival of organisms, including humans. Therefore, efforts to reduce CO2 emissions have been conducted by various methods, such as chemical, physical and biological methods, one of the most efficient methods to absorb CO2 gas is to use microalgae. Microalgae are photosynthetic organisms capable of absorbing CO2. Microalgae can also be converted into valuable products such as biofuels, biofertilizers, food, feed, medicines, and cosmetics through an integrated biorefinery concept. In the future, CO2 mitigation using microalgae will be massively studied, considering the many benefits obtained from the utilization of microalgae to reduce CO2 emissions in the world. Through the concept of biorefinery, microalgae can be processed into various derivative products that are useful for humans in the food, feed, health, industrial, medicine, and cosmetic sectors. This review will compare the effectiveness of CO2 absorption through terrestrial plants, microalgae, and microalgae-bacterial consortia to the possibility of its application and challenges.
Nouveautés en immunologie pédiatrique : Succès du dépistage néonatal et nouveaux déficits immunitaires
Authors: Blanchard Rohner Géraldine , Trück Johannes
Published: March 2024

Chaque année, de nouveaux déficits immunitaires sont identifiés au niveau moléculaire. Il s’agit de déficits immunitaires avec une présentation clinique souvent moins classique. En effet les patients touchés peuvent présenter des infections récurrentes ou sévères à un seul type de microbes ou alors des manifestations d’auto-immunité, ou d’auto-inflammation, ou des allergies, ou une insuffisance de la moelle osseuse et /ou une prédisposition aux cancers. Selon le type, les déficits immunitaires primaires ont une incidence qui varie entre 1:200 et 1:2000.
Arthrite juvénile idiopathique systémique, une mise au point
Authors: Welzel Tatjana , Woerner Andreas , Kaiser Daniela
Published: March 2024

Les manifestations de l’arthrite juvénile idiopathique systémique (AJIs) sont typiquement systémiques (p.ex. fièvre, érythèmes, hépatosplénomégalie, adénopathies, signes biologiques d’inflammation) et articulaires. La composante articulaire étant initialement parfois absente, le diagnostic représente un défi, un large spectre de diagnostics différentiels devant être pris en compte. Un diagnostic précoce ainsi qu’un traitement efficace sont importants, afin d’éviter des complications comme le syndrome d’activation macrophagique (SAM) et obtenir une rémission.
La prise en charge multidisciplinaire de l’hypophosphatémie liée au chromosome X (XLH): une mise au point
Authors: Goischke Alexandra
Published: March 2024

L’hypophosphatémie de transmission dominante liée à l’X (XLH), connue aussi sous le nom de rachitisme hypophosphatémique, diabète phosphaté ou rachitisme résistant à la vitamine D, est une maladie rare du métabolisme osseux. Elle se caractérise par une perte importante de phosphate par les reins, entraînant une hypophosphatémie, d’où le nom. Avec une prévalence de moins de 1-9 / 100’000 elle fait partie des maladies rares.