bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Late Conversion from Twice-Daily to Once-Daily Slow Release Tacrolimus on the Insulin Resistance Indexes in Kidney Transplant Patients
Authors: Cademartori Valeria , Massarino Fabio , Parodi Emanuele L. , Paoletti Ernesto , Russo Rodolfo , Sofia Antonella , Fontana Iris , Viazzi Francesca , Esposito Pasquale , Garibotto Giacomo
Published: February 2021

The use of tacrolimus (Tac) may be involved in the development of new-onset diabetes after transplantation (NODAT) in a dose-related manner. This study aimed to evaluate the effects of a standard twice-daily formulation of Tac (TacBID) vs. the once-daily slow-release formulation (TacOD) on the basal insulin resistance indexes (Homa and McAuley), and related metabolic parameters, in a cohort of kidney transplant patients. We retrospectively evaluated 20 stable renal transplant recipients who were switched from TacBID to TacOD. Blood levels of Tac were analyzed at one-month intervals from 6 months before to 8 months after conversion. Moreover, Homa and McAuley indexes, C-peptide, insulin, HbA1c, uric acid, triglycerides, low-density lipoprotein (LDL) and high-density lipoprotein (HDL)-cholesterol serum levels and their associations with Tac levels were evaluated. We observed a significant decrease in Tac exposure (8.5 ± 2 ng/mL, CV 0.23 vs. 6.1 ± 1.9 ng/mL, CV 0.31, TacBID vs. TacOD periods, p < 0.001) and no significant changes in Homa (1.42 ± 0.4 vs. 1.8 ± 0.7, p > 0.05) and McAuley indexes (7.12 ± 1 vs. 7.58 ± 1.4, p > 0.05). Similarly, blood levels of glucose, insulin, HbA1c, lipids, and uric acid were unchanged between the two periods, while C-peptide resulted significantly lower after conversion to TacOD. These data suggest that in kidney transplant recipients, reduced Tac exposure has no significant effects on basal insulin sensitivity indexes and metabolic parameters.
EFECTO PREDESINFECTANTE DEL OXICLORURO DE COBRE SOBRE HONGOS CONTAMINANTES EN SEGMENTOS NODALES DE Guadua angustifolia KUNTH, PARA SU ESTABLECIMIENTO IN VITRO
Authors: López Rodolfo
Published: February 2021

En el establecimiento in vitro de tejidos vegetales, se reporta la condición de aplicar protocolos de desinfección, con poca información acerca de procesos de predesinfección; en las diferentes etapas de micropropagación de Guadua angustifolia, se cuenta con reportes de contaminación por hongos y bacterias, estando los hongos más ligados a la etapa de establecimiento, mientras que la presencia de bacterias se registra en todas las fases in vitro. Para el establecimiento in vitro de explantes de guadua, en el Laboratorio de Biotecnología Vegetal, de la Corporación Autónoma Regional del Quindío, Colombia, se procedió a evaluar el fungicida comercial Oxi-cloruro de Cobre aplicado como pretratamiento de desinfección de segmentos nodales de guadua, seguido de un protocolo de desinfección ya establecido, que consistió en alcohol del 90% por 3 min, seguido de inmersión en NaClO del 3% por 10 min; la predesinfección se realizó mediante lavado con detergente comercial, en agua destilada estéril por 20 min; seguidamente se sometieron los diferentes segmentos nodales (juvenil, maduro y diferenciado) a inmersión durante 30 y 60 min en soluciones de los productos comerciales: oxicloruro de cobre y Agrodyne, y su mezcla. Los menores índices de contaminación por hongos, se lograron con segmentos noda-les juvenil y maduro, sometidos a oxicloruro de cobre, mientras que el segmento nodal juvenil presentó mayor contaminación por bacterias.
Sağ Ventrikül Çıkış Yolu Darlıklarının Tamirinde Homogreft ve Contegra Greft Kullanılan Hastaların Sağ Kalımının Karşılaştırılması
Authors: AMANVERMEZ ŞENARSLAN Dilşad , ALAYUNT Emin Alp
Published: February 2021

Giriş ve Amaç: Homogreftler veya ksenogreftler sağ ventrikül çıkış yolu (RVOT) darlıklarının tedavisinde günümüzde en sık kullanılan materyallerdir. Çalışmanın amacı RVOT tamirlerinde homogreft ve Contegra® Greft (ksenogreft) kullanılan hastaların mortalite oranlarını belirlemek ve sağ kalımlarını karşılaştırmaktır. Çalışmanın ikincil amacı ise mortalite için risk faktörlerinin belirlenmesidir.

Gereç ve Yöntemler: Çalışmaya üçüncü basamak sağlık kuruluşumuzda son yedi yılda RVOT darlığı nedeniyle homogreft veya Contegra® Greft kullanılarak RVOT rekonstrüksüyonu uygulanan hastalar dahil edilmiştir. Toplam 71 hastanın; 18’ine homogreft (%25,4) ve 53’üne (%74,6) ise Contegra® Greft ile RVOT rekonstrüksüyonu uygulanmıştır. Çalışma için yerel etik kurul izni alınmıştır.

Bulgular: RVOT darlığının en sık etiyolojik sebebi Fallot Tetralojisiydi. Contegra® Greft grubunun yaş ortalaması ve kullanılan greft çapları (t test, p
Design of Temperature-Responsive Cell Culture Surfaces for Cell Sheet Engineering
Authors: Akiyama Y.
Published: February 2021

Temperature-responsive cell culture surfaces, which modulate cell attachment/detachment characteristics with temperature, have been used to fabricate cell sheets. Extensive study on fabrication of cell sheet with the temperature-responsive cell culture surface, manipulation, and transplantation of the cell sheet has established the interdisciplinary field of cell sheet engineering, in which engineering, biological, and medical fields closely collaborate. Such collaboration has pioneered cell sheet engineering, making it a promising and attractive technology in tissue engineering and regenerative medicine. This review introduces concepts of cell sheet engineering, followed by designs for the fabrication of various types of temperature-responsive cell culture surfaces and technologies for cell sheet manipulation. The development of various methods for the fabrication of temperature-responsive cell culture surfaces was also summarized. The availability of cell sheet engineering for the treatment and regeneration of damaged human tissue has also been described, providing examples of the clinical application of cell sheet transplantation in humans.
Peningkatan Kualitas Manajemen Publikasi Ilmiah Menggunakan Metode Agile
Authors: Anoesyirwan Anoesyirwan , Madiistriyatno Harries , Mutmainnah Siti
Published: February 2021

Sebagai bentuk kesiapan dalam menghadapi era disruptif yang berkembang pesat, pengelolaan sistem penerbitan jurnal online dituntut untuk dapat menciptakan inovasi dalam manajemen jurnal serta mengoptimalkan kualitas sehingga dapat memberikan pelayanan terbaik. Permasalahan yang dihadapi dalam pengelolaan publikasi Ilmiah adalah perubahan requirement yang sulit dikendalikan dan kepuasan konsumen adalah fokus utama yang perlu diatasi. Sejalan dengan kegunaan dari metode Agile yaitu model kerangka kerja yang mampu mengakomodasi perubahan di setiap langkah prosesnya. Maka metode Agile merupakan pemodelan pengembangan sistem yang cocok dengan pengelolaan manajemen jurnal APTISI Transactions on Management (ATM). Hasil implementasi manajemen publikasi ilmiah menggunakan metode Agile diharapkan dapat menyesuaikan kebutuhan penulis dan berkualitas unggul.
Ser de clase media: Formación de clase en los residentes del conjunto residencial "Alemania" (Bucaramanga, Colombia)
Authors:   , Bacca Contreras Rafael Eduardo
Published: February 2021

La presente tesis indaga sobre la formación de clase media en los habitantes del Conjunto Residencial Alemania -ubicado en la ciudad de Bucaramanga, Colombia- desde una perspectiva de estructuración social con vínculos heterogéneos y especificidades contextuales. Para tal propósito, en un primer momento se realiza un recorrido por las principales teorías analíticas sobre la categoría clase media. Poniendo especial atención a sus resonancias y usos para Latinoamérica, Colombia y la ciudad de Bucaramanga. En un segundo momento, a partir de una contextualización macrosocial, se presenta la(s) situación(es) histórica(s) de la clase media para el país y la ciudad en cuestión, relacionando a esta clase social con un vínculo particularmente significativo: las residencias de tipo cerradas. Este análisis de cambios urbanísticos y clase media en Bucaramanga esencialmente, permite dar paso al tercer capítulo. En este los sujetos, indagados con entrevistas en profundidad y teniendo como enfoque a la clase media como proceso y estructuración social, explicitan sus experiencias y apropiaciones de clase social. Desde ahí se hizo posible hallar los vínculos y manifestaciones de formación de clase media en los moradores de Alemania, visibilizando su configuración particular de clase y haciendo un aporte a este fenómeno social a nivel local y nacional.
Effect of Soil and Fertilizer Treatment Systems on Agrochemical Properties of Fertility and Spring Wheat Yields
Authors: Носкова Е.В.
Published: February 2021

Многолетний стационарный полевой опыт проводился на дерново-подзолистой среднесуглинистой почве в Ярославской области. В статье представлены результаты исследований по изучению действия разных по интенсивности систем обработки почвы и удобрений на изменение агрохимических показателей плодородия почвы и урожайности яровой пшеницы. Отмечена динамика накопления гумуса в пахотном слое почвы при системе поверхностно-отвальной обработки на 0,17%, совместном внесении соломы и полного минерального удобрения – на 0,15%. Выявлен рост рН при системе ежегодной отвальной обработки, системах без удобрений и одной соломы. Динамике повышения содержания фосфора на 57,00 мг/кг способствовало совместное применение соломы с полным минеральным удобрением. Увеличению содержания обменного калия содействовали: система энергосберегающей поверхностно-отвальной обработки (на 0,92 мг/кг) и система «солома + NРК» (на 44,09 мг/кг). Отмечено увеличение урожайности зерна яровой пшеницы (на 2,04 ц/га) при применении системы энергосберегающей поверхностно-отвальной обработки почвы. Совместное использование соломы с полным минеральным удобрением достоверно повысило урожайность на 8,18 ц/га. Для дерново-подзолистой среднесуглинистой почвы с временным избыточным увлажнением рекомендуется применение системы энергосберегающей поверхностно-отвальной обработки почвы и совместное внесение соломы с полным минеральным удобрением.

Long-term stationary field experiment was carried out on soddy podzolic middle loamy soil in the Yaroslavl region. The article presents the results of research on the effect of soil and fertilizer treatment systems different in intensity on changing agrochemical indicators of soil fertility and spring wheat yield. Dynamics of humus accumulation in arable layer of soil at system of surface and moldboard tillage by 0.17%, combined application of straw and complete minerals - by 0.15% was noted. An increase in pH was revealed with an annual moldboard tillage system, systems without fertilizers and straw. The dynamics of the increase in phosphorus content by 57.00 mg/kg were facilitated by the joint use of straw with complete minerals. The increase in the content of exchangeable potassium was facilitated by: an energy-saving surface and moldboard tillage (by 0.92 mg/kg) and a "straw + NPK" system (by 44.09 mg/kg). There was an increase in the yield of spring wheat grains (by 2.04 c/ha) when using an energy-saving surface and moldboard tillage system. The combined use of straw with complete minerals significantly increased yield by 8.18 c/ha. For soddy podzolic middle loamy soil with temporary excessive moistening it is recommended to use a system of energy-saving surface and moldboard tillage and joint application of straw with complete minerals.
Heat-Exchange Surface Calculation of Heat-Conducting Medium and Grain Trashed Heap
Authors: Николаев В.А. , Кряклина И.В.
Published: February 2021

Для энергосбережения при сушке зерна в контактно-конвективной сушилке предлагается использовать тепло охлаждающей жидкости двигателя внутреннего сгорания. Жидкость поступает в трубки контактно-конвективной сушилки. Трубки теплоносителя расположены наклонно под углом 40° параллельно друг другу по всей ширине сушилки. Над ними, в шахматном порядке – паросборники. Над паросборниками установлен плавающий разравнивающий транспортёр, который изменяет своё положение в зависимости от объёма зерна в контактно-конвективной сушилке. Рассмотрена отдельная зерновка, движущаяся по поверхности трубки теплоносителя. В результате нагрева зерновки происходит её отпотевание – появление влаги на поверхности зерновки. Произведён теплотехнический расчёт поверхности теплообмена теплоносителя и зернового вороха, определено количество тепла, передающегося зерновому вороху в результате контактного теплообмена. Установлено, что использование тепла охлаждающей жидкости двигателя внутреннего сгорания в контактно-конвективной сушилке приводит к энергосбережению при сушке зерна.

For energy saving at grain drying in contact-convection drier it is proposed to use heat of cooling liquid of internal combustion engine. The liquid enters the tubes of the contact-convection drier. Heat carrier tubes are set at an angle of 40 ° parallel to each other along the full width of the drier. There are steam headers staggering above them. An amphibious leveling carrier is installed above the steam headers which changes its position depending on the volume of grain in the contact-convection drier. Separate caryopsis moving along surface of heat-conducting medium tube is considered. As a result of the heating of the caryopsis its sweating occurs – the appearance of moisture on the surface of the caryopsis. Thermotechnical calculation of heat-exchange surface of heat-conducting medium and grain trashed heap is performed, amount of heat transferred to grain trashed heap as a result of contact heat exchange is determined. It has been found that using the cooling liquid heat of the internal combustion engine in the contact-convection drier leads to energy saving when drying grain.
Impact of Probing-Prompting Learning Model towards Students’ Writing Speech Script Ability
Authors: Pahamzah John , Syafrizal Syafrizal
Published: February 2021

The aim of the research was to explore whether the probing/prompting learning model influenced Indonesian English as a Foreign Language students’ ability to perform a speech. The method used in this research was an experimental method with random cluster sampling of students from an Indonesian English as a Foreign Language school ­– Medang Gili Senior High. There were two 10th grade classes of 22 and 25 students. The results of the lottery performed on the available classes established X-B class as the experimental group and X-A class as the control group. Results of the script-writing test indicated that the average score was 79 out of 100 (with the lowest score of 65 and the highest score of 90) and the median and mode were 80.2 and 81.5, respectively. The ability to write scripts using expository models for speeches was tested among the control class. Another test prompted the use of probing prompting. The results of the hypothesis testing (t test) showed a significant level of 0.05, indicating the significant influence of using probing-prompting learning model (5.00 is greater than t table 2.026), so H0 was rejected and H1 was accepted. Ultimately, the use of probing/prompting learning models had a demonstrably positive impact on tenth graders’ abilities to write speeches during the 2019-2020 academic year.
Antibacterial Activity Tests of Staphylococcus Aureus and Phytochemical Screening in Family Asteraceae, Clusiaceae, Phyllanthaceae
Authors: Djarot Prasetyorini , Utami Novi Fajar , Veonicha Noerma , Rahmadini Anggita , Iman Afrizal Nur
Published: February 2021

Infection is a type of disease that affects many residents of developing countries, including Indonesia. One pathogenic bacteria that is quite dangerous and causes skin infections both sporadically and endemically is S aureus. Several studies intensively report that some of the Asteraceae, Clusiaceae and Phyllanthaceae family plants contain alkaloids, flavonoids, saponins and tannins that have potential as antibacterial S aureus. Therefore, this study aims to identify effective plants to deal with infections caused by S aureus bacteria. To this end, the ingredients used are the leaves of G. procumbens, E. scaber, G. mangostana, G atroviridis, G. xanthochymus, leaves and bark of A. neurocarpum. Plant material extraction was done by maceration using 90% ethanol solvent. Next, an antibacterial test was conducted, which was begun by testing the Minimum Inhibitory Concentration followed by testing the Obstacle Area Width. The Minimum Inhibitory Concentration test was carried out using the agar dilution method, and the Obstacle Area Width test was carried out with paper diffusion discs. The results showed that all the plants have potential as antibacterials, and the mangosteen leaf extract has the largest Obstacle Area Width of 5.1 mm with a concentration of extract of 30% and a fairly strong inhibitory ability.
Influence research of an α–form alumina type on the properties of samples from vibrocasting mullite corundum granular masses
Authors: Martynenko V. V. , Kushchenko P. A. , Shulyk I. G. , Kushchenko K. I. , Krakhmal Yu. O. , Tkachenko L. P.
Published: February 2021

The technology of refractories vibrocasting was developed by JSC "URIR named after A. S. Berezhnoy" in particular highly refractory mullite corundum crucibles for melting of heat-resistant alloys in induction furnaces. At manufacturing of highly refractory vibrocasting mullite corundum refractories a-form alumina, as a dispersion binder, which milling to a particles size of less than 10 μm (the content of particles less than 4 μm in such alumina is more than 50 %) is used. For improvement the casting characteristics of vibrocasting masses dispersants are used. At research milling kinetics alumina of all brands was milling in a vibration mill for a specified time. For this research a certain amount of the investigated alumina of each brand was loaded into a vibration mill, and after a specified grinding time (30, 45, 60, 75 and 90 min), a sample of alumina after milling was taken in a specified amount. In this work, the kinetics of changes the dispersion of alumina (S, N and NR brands) during their milling was studied. The dispersion of alumina which were needed (the content of particles less than < 10 μm in such alumina is not less than 90 %, the content of particles less than < 4 μm — not less than 50 %) was achieved in almost the same milling time was found (~ 45 min). With a further increase of milling time to 60, 75 and 90 minutes, the dispersion of alumina N and NR brands increases in comparison with alumina S brand and after 90 minutes of milling, the content of particles < 4 μm in alumina, respectively, is ~ 60, ~ 75 and ~ 80 %. After fired at a temperature of 1580 °C the properties of vibrocasting mullite corundum samples, which contain alumina S, N and NR brands, are characterized by a high level of apparent density (above 3 g/cm3), open porosity (less than 16 %) and cold crushing strength (above 140 N/mm2). The high properties make it possible to use a-form alumina N and NR brands along a-form alumina S brand in the technology of vibrocasting mullite corundum refractories, including the highly refractory mullite corundum crucibles.
The Effects of Leaderships Styles, Work-Life Balance, and Employee Engagement on Employee Performance
Authors: Katili Putiri Bhuana , Wibowo W. , Akbar Maruf
Published: February 2021

Employee Engagement is an important strategy on increasing company performance. The aims of this research is to elaborate influences of  leadership styles and work- life balance to the employee engagement; also influence of employee engagement to the employee performance. To achieve this aim, the data was collected from 204 employees using questionnaire as instrument of research. The collected data was analyzed using SPSS and Structural Equation Modeling. This research conducted in  steel industry. From this research can be concluded that  work-life balance   have most significant influence to employee engagement, and employee engagement have strong influence to the employee performance. By increasing leadership  styles and work-life balance , the company could improve employee engagement. Therefore, the company management can utilize this research result for increasing employee performance and  company competition.
DPM Dua Mode Dilengkapi Thermohygrometer dan Pemilihan Tekanan (Positive Pressure)
Authors: Kusumadewi Ketut Dyah , Syaifudin Syaifudin , Indrato Tri Bowo
Published: February 2021

Kalibrasi merupakan suatu kegiatan teknis yang terdiri atas penetapan, penentuan suatu atau lebih sifat dan karakteristik  dari suatu produk, proses atau jasa sesuai dengan prosedur khusus yang telah ditetapkan. Digital Pressure Meter (DPM) merupakan alat yang digunakan untuk mengukur tekanan positif dan negatif pada alat Kesehatan. Tujuan dibuatnya alat Digital Pressure Meter (DPM) Dua Mode dilengkapi Thermohygrometer dan Pemilihan Tekanan (Positive Pressure) sebagai solusi untuk menciptakan perangkat pemantauan tekanan darah yang lebih informatif efektif serta akurat dalam pengukurannya. Kontribusi penelitian ini adalah sistem dapat dijalankan dengan menggunakan sensor tekanan tiup, hasil ukur bisa dikonversi kesatuan kPa dan ditampilkan di LCD TFT Nextion 2,4 inch. Agar sistem berjalan maka diperlukan tekanan tiup yang sesuai dengan alat tensimeter itu sendiri. Menggunakan sensor MPX 5050GP sebagai sensor tekanan positif. Membutuhkan tekanan maksimal 300 mmHg. Menggunakan sensor DHT 22 untuk suhu kelembaban. Alat ini juga di lengkapi degan timer uji kebocoran. Display yang digunakan pada modul ini adalah LCD TFT Nextion 2,4 inch Setelah melakukan proses pengukuran ke alat tensimeter air raksa  sebanyak 6 kali  didapatkanhasilterkecil 0 mmHg pada tekanan 0 mmHg dan yang terbesar 298.0 mmHg pada tekanan 300mmHg. Simpangan rata-rata terbesar ini dikarenakan adanya kebocoran tekanan antara selang penghubung output modul dan penghubung ke alat tensimeter. Berdasarkan pengambilan data suhu kelembaban yang dilakukan pada ruangan  diperoleh 31̊C pada suhu  dan 87% pada kelembaban. Dari penelitian ini Rangkaian keseluruhan  yang dibuat sudah sesuai dengan kebutuhan modul DPM Hasil penelitian menunjukkan bahwa modul bisa digunakan untuk proses kalibrasi pada alat tensimeter.
Oxidação de lipídeos e as implicações na nutrição e saúde de animais de produção
Authors: Baron Lana Flávia , Pazinatto Rafael , Baron Camila Paula
Published: February 2021

O processo de oxidação é uma das principais reações de deterioração de alimentos. A oxidação tem grande influência no valor nutricional e na qualidade de produtos que são utilizados na nutrição animal, principalmente quando se fala em óleos utilizados na ração. A utilização de lipídeos tem o objetivo de possibilitar melhor desempenho e saúde ao animal, fornecendo-lhe mais energia. Esta revisão tem por objetivo abordar, de maneira geral, a importância dos lipídeos, como ocorre sua oxidação, o uso de antioxidantes e as implicações dos lipídeos para a nutrição e saúde de animais de produção. Os lipídeos são substâncias que possuem alto valor nutritivo e energético. Porém, quando a questão é nutrição, o uso de lipídeos oxidados altera as propriedades organolépticas da ração, como presença de odor, sabor e alteração da viscosidade do óleo, sendo característico o ranço. Ademais, pode levar ao desenvolvimento de alterações fisiológicas indesejadas e prejuízos nutricionais, além de formar substâncias tóxicas que possuem grande influência na ocorrência de doenças.
Caminhos para a produção de leite em pequena escala
Authors: Leite José Luiz Bellini
Published: February 2021

A situação da cadeia produtiva de leite no Brasil é discutida quanto à estrutura de produção, à dinâmica em curso, aos desafios e às consequências previsíveis para a produção de leite em pequena escala. Ganhadores e perdedores são apontados no processo de inovação tecnológica que está em marcha acelerada nessa cadeia produtiva. A redução do número de produtores foi da ordem de 13%, no geral, e de 31% no estrato de menor escala de produção de 2006 para 2017, indicando os vetores-chave nesse processo. Assim, sugerem-se uma forma de organização e um conjunto de processos para auxiliar os produtores de diversas escalas de produção e incentivá-los a terem determinação para enfrentar o problema, abandonar a pobreza e permanecer no negócio.
Determinantes do consumo de leite de cabra e derivados na Zona da Mata mineira
Authors: Delgado Junior Idílio José , Siqueira Kennya Beatriz , Ramalho Breno Canto Ferreira , Chaves Davi Oliveira
Published: February 2021

O estado de Minas Gerais está entre os principais produtores de leite de cabra no Brasil, e a Zona da Mata mineira é uma importante região na fabricação de derivados caprinos. Apesar da boa performance como fornecedora, a região apresenta baixo consumo do leite de cabra e, até o momento, nós não conseguimos encontrar nenhum estudo referente ao comportamento de compra dos consumidores desse produto. Nesse sentido, o objetivo do presente trabalho foi avaliar os fatores que afetam o consumo do leite de cabra e seus derivados na região da Zona da Mata mineira, assim como delinear o perfil de consumidores e potenciais consumidores desses produtos. A pesquisa contou com a participação de 235 pessoas residentes em vários municípios da região e evidenciou que desconhecimento e falta de hábito de consumo da população são os principais fatores que impedem o crescimento do consumo na região. O fato de o leite de cabra ser considerado um produto saudável é a principal justificativa para sua compra, no entanto, os resultados indicam que idosos com renda mais elevada têm maior propensão a consumir leite de cabra e seus derivados na região. A definição desse público-alvo pode direcionar campanhas de marketing e contribuir para o desenvolvimento desse mercado.
Análise exploratória de dados espaciais da produção de café no estado do Paraná, 1980-2018
Authors: Pompermayer Sesso Patricia , Pereira Luiz Filipe Protásio , Sesso Filho Umberto Antonio , Zapparoli Irene Domenes
Published: February 2021

O objetivo deste estudo foi realizar a análise exploratória dos dados espaciais (Aede) da produção de café dos municípios do estado do Paraná, no período 1980-2018. A fonte dos dados foi o Instituto Paranaense de Desenvolvimento Econômico e Social (Ipardes). Nesse período, a produtividade da cultura do café no estado do Paraná aumentou de cerca de 900 para 1.500 kg ha-1, com tendência de crescimento de 16,48 kg ha-1 por ano. A introdução de novas tecnologias na década de 1990 propiciou menor risco aos produtores, e o aumento da produtividade implicou a redução do custo médio da saca de café e o aumento da competitividade. No período de análise, ocorreu o deslocamento da maior parte da área colhida e da produção para as Mesorregiões Norte Pioneiro e Norte Central, que passaram a concentrar a produção e os municípios mais produtivos. Verificou-se uma autocorrelação espacial da produtividade dos municípios, e identificaram-se agrupamentos espaciais Alto-Alto dos municípios localizados, principalmente, nas Mesorregiões Norte Pioneiro e Norte Central do estado do Paraná, no ano de 2018.
Home respiratory rehabilitation: a purposes literature review focusing on the clinical pathway management
Authors: Civitillo Claudio , Romano Angelo , Di Lorenzo Luigi
Published: February 2021

Clinical Care pathways, also known as critical pathways, integrated care pathways, case management plans, clinical care pathways or care maps, are used to systematically plan and follow up a patient focused care program. Clinical pathways are used all over the world and so for respiratory rehabilitation pathways (RR) and the importance of knowledge and learning Evidence Based Practice (EBP) is well known and mandatory. However, the EBP acquisitions of the home RR model and the knowledge of Clinical Care Pathways (PCA) are poorly defined.
PERAN LEMBAGA KEUANGAN MIKRO PERTANIAN BAGI KETAHANAN PANGAN PETANI INDONESIA
Authors: MT., M.P. Hasanawi , Hasanawi Asyrafinafilah , Kesumawati Neti
Published: February 2021

Kemiskinan dan kelaparan yang ekstrim didominasi di kawasan perdesaan, dengan proporsi keluarga petani yang sangat signifikan termasuk dalam masyarakat tidak mampu (miskin) dan mengalami kelaparan. Dengan demikian, pemberantasan kemiskinan dan kelaparan secara integral terkait dengan peningkatan produksi pangan, produktivitas pertanian dan pendapatan perdesaan. Selain itu, kondisi iklim yang tidak menentu secara langsung mempengaruhi keberlangsungan pertanian di Indonesia. Indonesia harus mampu menyediakan pangan yang cukup bagi seluruh rakyat dan akses pangan dengan harga terjangkau dengan perubahan yang berisiko tinggi. Berkaitan dengan hal tersebut, pengetahuan mengenai klimatologi penting dilakukan untuk mengantisipasi seperti perubahan iklim. Saat beradaptasi dengan perubahan iklim, kegiatan pertanian dibarengi dengan kegiatan perlindungan dan penguangan risiko hingga level yang paling rendah. Sehingga muncul asuransi usahatani yang bertujuan untuk melindungi pertanian, berbagi risiko, dan memihak petani. Asuransi usahatani, khususnya, berlaku untuk berbagi risiko gagal panen yang disebabkan oleh banjir, kekeringan, serta serangan hama dan penyakit. Penelitian ini menggunakan analisis pada data sekunder tentang ekonomi dan sistem keuangan Indonesia dan informasi yang dikumpulkan dalam wawancara dengan individu-individu kunci (keypersons) di Kementerian Pertanian, Jakarta. Untuk memperjelas data tersebut, dipilih satuKabupaten di provinsi Jawa Barat, Kabupaten Cirebon, dan dua Kabupaten di provinsi Jawa Tengah, Kabupaten Boyolali dan Kabupaten Semarang. Ketiga wilayah tersebut dipilih karena memiliki perkembangan sistem keuangan terutama pertanian daerah yang dinamis, dukungan pemerintah untuk memberikan subsidi pertanianyang aktif. Namun, dikarenakan tidak adanya bank pertanian di Indonesia, lembaga keuangan mikro eksisting diharuskan menyediakan dana yang cukup untuk menutupi biaya produksi. Untuk tindak lanjut jangka pendek, Program Pengembangan Agribisnis Pedesaan (PUAP) saat ini diharapkan dapat membantu petani melalui lembaga keuangan mikro dalam mendanai kegiatan pertanian. Peran keuangan mikro merupakan bagian dari strategi ketahanan pangan dan sangat penting untuk membantu petani dalam meminimalisir efek risiko gagal panen. Praktik pertanian berkelanjutan dan sistem pangan, termasuk produksi dan konsumsi, sebaiknya dilaksanakan dalam perspektif yang holistik dan terintegrasi. Kata kunci : asuransi pertanian, perlindungan pertanian, risiko gagal panen.
UPAYA MENINGKATKAN AKTIVITAS DAN HASIL BELAJAR SISWDALAM PEMBELAJARAN BIOLOGI DENGAN MENGGUNAKAN METODE GROUP INVESTIGATION (GI) DENGAN PENDEKATAN LINGKUNGAN PADA POKOK BAHASAN CIRI – CIRI MAHLUK HIDUP DI SMP N 2 CURUP
Authors: Sari Ria Puspita , Irwandi Irwandi
Published: February 2021

This study aims to improve the activities of teachers and students towards biology learning and to improve the learning outcomes of teachers and students in biology learning by using the cooperative group investigation method on the environmental approach on the subject matter of the characteristics of living things in class VII F at SMP N 2 Curup. This type of research in the form of class action carried out in two cycles, each cycle has stages, namely planning, implementation, observation and reflection. Data collection techniques include teacher and student observation sheets and student evaluation test sheets. The observation sheet is used to find out the activities of the teacher and students, while the evaluation test sheet is to find out the improvement of student results. Observation data and student test data were analyzed descriptively by calculating averages. Based on the results of the calculation of the average score of the activities of the first cycle teacher is 20 categorized as good and student activity scores 20.5 with a good category. And in cycle II the teacher's activity gets a score of 24 and the student's activity gets a score of 24 with a good category. And an increase in student learning outcomes in the first cycle with an average of 77.17, while in the second cycle with an average value of 83.30. For mastery learning in the first cycle 76.93% while completeness learning in the second cycle 93.30%. The increasing activity of teachers and students in the second cycle shows that the use of the group investigation method on the subject of the characteristics of living things can improve the learning outcomes of Grade VII F students in SMP N 2 Curup. Keywords: Group Investigation, Teacher and Student Activities, Learning Outcomes.
Penerapan konsep gamification pada aplikasi e-commerce untuk umkm makanan
Authors: Ningsih Norma
Published: February 2021

Penjualan adalah kegiatan antara penjual dan pembeli dimana penjual menjual barang dan jasa yang bertujuan untuk mendapatkan laba dari transaksi yang terjadi. seiring berkembangnya teknologi sistem penjualan tidak bisa lepas dari teknologi yang sudah menjadi kebutuhan agar bisnis bisa tetap berkembang dan bertahan. Terdapat berbagai macam pemanfaatan teknologi informasi dalam bidang bisnis, salah satunya adalah perdagangan elektronik atau dapat disebut e-commerce. untuk menguatkan motivasi dari pelanggan untuk terus melakukan pembelian dan meningkatkan loyalitas pelanggan maka dikembangkan aplikasi e-commerce yang menerapkan konsep gamification. unsur game yang dipakai pada aplikasi ini adalah rating dan badges pada transaksi penjualan. dari hasil ujicoba menggunakan blackbox testing aplikasi memiliki tingkat kesesuaian fungsi yaitu 100%.
Penerapan Pendidikan Jarak Jauh (PJJ) Dimasa Pandemi Covid-19 pada SIDH Belanda dan SIKL Malaysia
Authors: Mubarok Husni , Swastika Yasinta Indra , Ainun Ayu , Hamdanah Siti Umi , Lestari Putri Diana , Saifuddin Muhammad Alif
Published: February 2021

The covid-19 pandemic caused the elimination of all activities that are usually carried out by almost everyone in the world, especially learning activities at various levels.  Based on the Higher Education Law number 12 of 2012, article 31 concerning Distance Education (PJJ) is a learning process that is carried out remotely through the use of various communication and information media.  Therefore, since the covid outbreak, distance education is now widely applied in the learning process almost all over the world.  This study aims to determine the application of distance education in SIDH Netherlands and SIKL Malaysia during the pandemic, and to find out the obstacles in the application of distance education in SIDH Netherlands and SIKL Malaysia during the pandemic.  The method used in this research is descriptive qualitative method.  Data collection techniques in this study using interview techniques.  The results of the study state that SIDH in the Netherlands and SIKL Malaysia have implemented the PJJ (Distance Education) system since 2008, with Distance Learning being used to do this, automatically during this pandemic, students are not surprised by the online learning provided.  teachers (educators), but there are also some obstacles faced during the teaching and learning process during the pandemic.  Whereas in SIKL Malaysia, distance education was implemented when there was covid-19, so all students study at their respective homes.  In its application, there are several obstacles in the learning process, one of which is signal constraints. The teachers from the two scools have coshen the best method for their students so that learning can be carried out optimally. And it is hoped that in learning to apply health protocols so that students and teacherscan carry out learning activities comfortably.
COMPARISION OF VARIOUS DOSES OF INTRAVENOUSLY ADMINISTERED
DEXMEDETOMIDINE WITH FENTANYL ON HAEMODYNAMICS TO INTUBATION
IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANESTHESIA
Authors: kumar Vikas , Sinha Ritesh Kumar , Prasad J.
Published: February 2021

Background: During general anesthesia , direct laryngoscopy and intubation results in a profound
sympathoadrenal response which leads to tachycardia , hypertension and in predisposed individuals
may lead to myocardial ischemia and arrhythmias. Various drugs such as opioids, lignocaine, propofol, beta blockers, alpha
agonists have been used to minimize these adverse responses. Methods: 90 patients ASA1, ASA2 scheduled to undergo
elective and emergency surgery under general anaesthesia were enrolled in double blind prospective randomized controlled
trial. ey were randomly allocated to one of the following groups. Group A received 2 micro gram/kg fentanyl intravenously10
minutes before induction. Group B received 2 micro gram/kg fentanyl and 0.5 microgram/kg dexmedetomidine intravenously
10 mins prior to induction. Group C received 2 mico gram/kg fentanyl and 1 microgram/kg dexmedetomidine i.v. 10
minutes prior to induction. Results: Both study groups(B & C) were comparable with respect to there heart rate at base line, 1
minute,2.5 minutes, 5 and 10 minutes after administration of the study drug. Group C(Dexmedetomidine 1 g) demonstrated a
greater suppression of chronotropic response to intubation as compared together two groups. Both the groups (B & C) were
comparable to their SBP at base line 5 and 10minutes Group C demonstrated a better suppression of the pressor response to
intubation compared to other two groups
Old Russian Translation of Cosmographia, sive De Situ Orbis by Pomponius Mela: Reception of Renaissance Culture in Muscovy (15th-17th Centuries)
Authors: Matasova Tatiana
Published: February 2021

The article deals with the results of the analysis of the Old Russian translation of the First book of Cosmographia by Pompons Mela. Mela’s Cosmographia was admired and praised by humanists. The research of the way the text was comprehended and interpreted in Muscovy demonstrates the original features of the perception of the Renaissance traditions, ideas and values by Russian intellectuals. The study reveals that the comprehension of Mela’s information was characterized by traditional manner of pursuit of biblical analogy. Thus, even the close acquaintance with the Renaissance culture did not change the essence of the Russian Medieval Orthodox culture.
Artistic Expression of the Translatio imperii Concept in the Latin Epic Poetry of the Polish-Lithuanian Commonwealth in the 16th Century and the European Literary Context
Authors: Nekraševič-Karotkaja Žanna
Published: February 2021

In this article the author analyzes how the Renaissance epic poetry of the Polish-Lithuanian Commonwealth approaches the theme of translatio imperii, which is a concept and a political stereotype of transfer of metaphysical world domination from country to country. After the fall of Constantinople (1453), the concept of translatio imperii gradually lost its universal character and was interpreted within the confines of a nation. Among the analyzed poems are: Bellum Prutenum (1516) by Ioannes Visliciensis and Radivilias (1592) by Ioannes Radvanus. The artistic expression of both the “Jagiellonian” and Lithuanian (i.e., Grand Duchy of Lithuania) patriotism, which incorporated the concept of translatio imperii, had an enormous impact on the formation of the national identity of the Belarusian, Lithuanian, and Polish peoples.
Classical Tradition in Czech Renaissance and Baroque Literature
Authors: Kysučan Lubor
Published: February 2021

The study deals with the influence of the classical tradition on Czech literature of the Early Modern Period (Renaissance, Baroque). The article demonstrates this influence through examples of the use of selected motifs from ancient history in all of the main genres of the literature of that era: homily, legend, school drama, poetry and educational literature. The study also analyses the educational background of the authors and readers of the era and their attitude to ancient history; the ways of mediation and making use of ancient motifs in the literature; and the influence of ancient historiography on Renaissance and Baroque culture and interpretation of history.
Humanism and the Renaissance in Recent Histories of Ukrainian Literature
Authors: Siedina Giovanna
Published: February 2021

In this article, the author analyzes how the broad theme of the reception of Humanism and Renaissance is treated in two important histories of Ukrainian literature, respectively Muza Roksolans’ka. Ukrajins’ka literatura XVI-XVIII stolit’ by Valerij Ševčuk (Kyiv, “Lybid'”, 2004-2005), in two volumes, and Istorija ukrajins’koji literatury in twelve volumes (2014-) published by the publishing house of the Academy of Sciences of Ukraine Naukova Dumka. The disappearance of Soviet ideological constraints has brought about the emergence of various aspects of this theme: the multilingualism (especially as regards literature written in Latin), the multiple identity of writers of the so-called Pohranyččja, the literature written in Latin, are just a few. However, some aspects still need to be addressed: among then the supranational approach should be adequately considered when dealing with the spread of Humanism-Renaissance.
A Bad Year? Climate Variability and the Wine Industry in Chile
Authors: Haddad Eduardo , Aroca Patricio , Jano Pilar , Rocha Ademir , Pimenta Bruno
Published: February 2021

Short-term climate conditions may affect crop yields and vintage quality and, as a consequence, wine prices and vineyards’ earnings. In this paper, we use a Computable General Equilibrium (CGE) model for Chile, which incorporates very detailed information about the value chain of the wine sector in the country. Using information for the 2015-2016 harvest, we calibrate climate variability shocks associated with a “bad year” for the wine industry in Chile, when premature rains occurred in important wine regions, reducing the area harvested and leading to wines with less concentrated flavors, particularly for reds. We model the climate shocks as a productivity change in the grape-producing sector (quantity effect). Moreover, we model quality effects as a shift in the foreign demand curve for Chilean wine. Given the specific economic environment in the model and the proposed simulation, it is possible to note the reduction of Chilean real GDP by about 0.067%. By decomposing this result, we verify that the quality effect has a slightly greater weight compared to the quantity effect.
The Role of Context Definition in Choice Experiments: a Methodological Proposal Based on Customized Scenarios
Authors: Boncinelli Fabio , Contini Caterina , Gerini Francesca , Romano Caterina , Scozzafava Gabriele , Casini Leonardo
Published: February 2021

One of the most critical points for the validity of Discrete Choice Experiments lies in their capability to render the experiment as close to actual market conditions as possible. In particular, when dealing with products characterized by a large number of attributes, the construction of the experiment poses the issue of how to express the choice question providing sufficient information. Our study verifies the role of scenario definition in choice experiments and proposes a methodology to build customized scenarios by eliciting responses from interviewees on the main choice criteria, which makes it possible to render the conditions of the experiment more realistic. This methodology is applied to the case study of wine and is introduced by a systematic review of the Discrete Choice Experiments conducted on wine. The findings show that customized scenarios result in different preference estimates compared to the conventional approach. In particular, we found a significant decline in the importance of the price attribute, which could be attributed to a better definition of the product being evaluated. Moreover, the methodology is capable of gathering information on the decision-making process that would otherwise remain unobserved and that can be used for a better segmentation analysis.
Sparkling Wine International Market Structure and Competitiveness
Authors: Thome Karim Marini , Paiva Vitoria A. Leal
Published: February 2021

This paper aims to analyse the Sparkling Wine international market structure and competitiveness, focusing on the 2004–2018 period. It used the data regarding exports and imports of sparkling wine available in the International Trade Centre’s Trade Map database. The method used to examine sparkling wine’s international market structure and competitiveness consisted of calculation of: (i) Revealed Comparative Advantage (RCA); (ii) Relative Position in the Market (RPM); (iii) Hirschman-Herfindahl Index (HHI); and (iv) Net Export Index (NEI). The paper analyses the growth of the sparkling wine trade worldwide. It demonstrated that France had the greatest relative position in the market, followed by Italy and Spain. This same sequence was found in the revealed comparative advantage, highlighting the increased Italian export level. A high export market structure concentration was also shown. On the other hand, there was an unconcentrated import market structure, and, according to the NEI, it was possible to identify three groups composed of actors who were stable in terms of: i) exports based on domestic production (France, Italy and Spain); ii) trade, reflecting re-export (Singapore and the Netherlands); iii) imports, with strong domestic consumption (Germany, the United Kingdom, the United States of America, Australia, and Belgium).
The Role, Scope and Management of R&D and Innovation in the Wine Sector: an Interview with Antonio Graca
Authors: Hayes Peter
Published: February 2021

Antonio Graca is Director of Research and Development at SOGRAPE VINHOS and an eminent figure in the Wine Business. With this extensive interview, he shares his thoughts and views on many key aspects of the business, starting with the role of R&D and innovation and the connection between academic research and the operators of the wine sector. The experience and knowledge that emerges from this in-depth conversation can represent a precious source of inspiration for researchers, managers and all the stakeholders in the sector, as it sheds a light on many key issues in the way to success in the wine business.
CORPORATE SOCIAL RESPONSIBILITY PRACTICES AS MANAGEMENT INNOVATIONS: ADOPTION AND CONSEQUENCES
Authors:   2-year undergraduate student of the direction of Management, Department of General and Strategic Management, Samara National Research University named after academician S.P. Korolev, Samara, Russia, RADAEVA YU. O.
Published: February 2021

The article discusses approaches to defining the essence of the concept of "corporate social responsibility". The main effects of corporate social investment for companies, contact audiences and the state level are outlined. The central principles of corporate social responsibility are highlighted, reflecting the dual nature of social investments.
METHODOLOGY FOR ASSESSING INNOVATION ACTIVITY BASED ON LATENT RESERVES
Authors:   Senior Lecturer of the Department of State and Municipal Administration of the Federal State Autonomous Educational Institution of Higher Education of the Samara National Research University named after academician S.P. Korolev, Samara, Russia, YUKLASOVA A. V.
Published: February 2021

In the article, based on the results of the analysis of methods for assessing the latent reserves of innovative activity of enterprises, their shortcomings are revealed, namely: complexity, labor intensity, subjectivity in the formation of results; high cost of software products that make it possible to facilitate calculations. Therefore, the prospects for further research are the creation of a methodology for calculating latent reserves in the implementation of the concept of sustainable development of innovative activity of an enterprise, which will be publicly available for ease of calculation.
OPTIMIZATION OF TAX POLICY IN THE PERIOD 2019-2024: ECONOMIC AND SOCIAL ASPECTS
Authors:   doctor of economic Sciences, state Councilor of the Russian Federation, class 2, Professor, Department of Economics and Finance of the public sector, Institute of public administration and management of RANEPA under the RF President, Moscow, Russia, PRONINA L. I.
Published: February 2021

The article examines the prospects for budget planning for 2021-2023, analyzes the state and development of tax legislation in 2019-2020, and the modification of tax policy in the period 2021-2023, including on the basis of protection and promotion of capital investments. An assessment of the effectiveness of tax incentives and other incentive mechanisms is proposed.