bluuebunny/crossref_metadata_2025 huggingface dataset:
A sustentabilidade das práticas de espeleoturismo no município de Laranjeiras, Sergipe
Authors: Donato Christiane Ramos , Andrade Isabel Cristina Barreto , Becker Michele Amorim , Carvalho Emanuella Santos de , Macedo Heleno dos Santos
Published: May 2019

A relação existente entre o ser humano e as cavernas existe desde as civilizações antigas. As cavidades naturais, suas lendas, mitos e religiões associadas indicam o tipo de relação entre esses ambientes e a população do seu entorno. Dentre as formas de visitação a cavernas, temos o espeleoturismo, uma modalidade do turismo sustentável em que visitantes são guiados por profissionais qualificados para vivenciarem experiências dentro do ambiente cavernícola e no seu entorno. Para analisar os graus de sustentabilidade do espeleoturismo em cavernas do município de Laranjeiras/Sergipe, a metodologia foi organizada de acordo com os objetivos específicos, utilizando para isso, o método de avaliação potencial de espeleoturismo, em que suas deliberações foram adaptadas à realidade do município estudado e o uso de um questionário, para reconhecer a percepção socioambiental dos moradores de Laranjeiras sobre as cavernas e seu entorno. Os resultados apontam que nenhuma das cavernas pesquisadas obteve potencial absoluto, intenso ou alto para espeleoturismo. A Gruta da Matriana, a Gruta Raposinha e a Gruta da Pedra Furada possuem 50% de potencial, classificando-as como de média potencialidade. A Gruta Aventureiros, a Gruta da Pseudomatriana e a Gruta dos Orixás possuem 33,33% de potencial, classificando-as, junto com a Gruta da Raposa e a Gruta do Tramandaí com 22,22% de potencial, em potencialidade moderada. A Gruta da Janela foi a única considerada inapta ao turismo, pois apresenta risco de contaminação patológica por Loxoceles sp. (aranha-marrom) e Lutzomyia sp. (mosquito-palha).
Registro de mamíferos fósseis da Lapa do Bode, Ituaçu, Bahia
Authors: Leoni Ronaldo Araujo , Silva Laís Alves
Published: May 2019

O presente trabalho realizou a identificação taxonômica de mamíferos fósseis de cinco taxa pertencentes aos gêneros: Alouatta, Myocastor, Tamandua, Pecari e Tapirus, encontrados na gruta Lapa do Bode localizada no município de Ituaçu-BA. Os fósseis foram transportados e triados no Laboratório de Ecologia e Geociências localizado na Universidade Federal da Bahia, Campus Anísio Teixeira, Instituto Multidisciplinar em Saúde, Vitória da Conquista. Os táxons foram identificados em sua maioria por uso da fórmula dentária, características morfometrias e morfológicas descritas na literatura e/ou comparação com espécimes da coleção do Laboratório. Os materiais variaram em estado de preservação, logo o conjunto faunístico pode não representar uma única comunidade. Estudos futuros poderão corroborar a hipótese apresentada.
Notas sobre a atividade antileishmania e citotóxica de análogos da piplartina
Authors: De Araújo-Vilges Keline Medeiros , Oliveira Stefan Vilges , Leite José Roberto de Sousa Almeida , Kuchelhaus Selma Aparecida
Published: May 2019

As leishmanioses são doenças parasitárias negligenciadas que afetam uma proporção significativa da população humana global. Muitos dos medicamentos disponíveis são tóxicos, caros e frequentemente ineficazes. A piplartina é uma amida extraída da espécie Piper tuberculatum que apresenta diferentes atividades biológicas, tendo destaque para ação antitumoral, antifúngica e antiparasitária. A utilização de substâncias sintetizadas a partir do modelo da piplartina pode ser importante para o desenvolvimento de novas drogas. O presente estudo avaliou o efeito dos análogos (A, B e C) da piplartina, em cultivos de Leishmania amazonensis e em células peritoneais de camundongos swiss. Todas as concentrações utilizadas de A, B e C diminuíram o percentual de formas promastigotas de L. amazonensis e também a viabilidade das células peritoneais, sendo a amida B a que apresentou melhor atividade biológica. Novos ensaios serão necessários para avaliar o efeito desses análogos sobre os macrófagos infectados, levando em consideração a modulação da resposta imune.
Percepção de professores sobre a educação inclusiva em uma instituição de nível superior no semiárido paraibano
Authors: Almeida Elzenir Pereira de Oliveira , Oliveira José Lucas Santos , Alves Cynthia Arielly Alves , Santos Thayanna Maria Medeiros , Silva Edevaldo
Published: May 2019

O objetivo deste estudo foi conhecer a percepção de professores de uma instituição de nível superior no semiárido paraibano sobre a Educação Inclusiva. Para a coleta de dados, foram aplicados questionários a professores do ensino superior com 10 questões/afirmativas, distribuídas em discursivas (6) e objetivas na escala de Likert (4). Esse método permite descobrir graus de opinião que podem fazer a diferença para entender o feedback recebido e foi aplicado com cinco níveis de resposta. O número amostral foi de 27 professores entrevistados que lecionam disciplinas em cursos diversos. Os dados reportaram que os professores lecionam a alunos com Necessidades Educacionais Especiais com deficiências intelectuais, tais como autismo (11,7%) e déficit de aprendizagem (7,4%), e que buscam formas de inclusão desses alunos por meio de metodologias diferenciadas, durante o ensino das disciplinas, tendo como objetivo de superar as limitações dos alunos. 74,0% (n = 20) dos professores nunca visitou instituições que atendam apenas alunos com Necessidades Educacionais Especiais e o mesmo percentual nunca participou de nenhuma capacitação para trabalhar com alunos que possuam essas necessidades. 14,8% (n = 4) dos professores discordaram que podem ter em algum momento alguma deficiência. A percepção sobre a importância da inclusão de alunos com Necessidades Educacionais Especiais no nível superior deve estar presente desde a formação inicial do professor. A capacitação profissional do docente irá minimizar as dificuldades encontradas por esses alunos em questão após ingressar na universidade, evitando assim a evasão dos mesmos.
Stable Non-symmetric Coupling of the Finite Volume Method and the Boundary Element Method for Convection-Dominated Parabolic-Elliptic Interface Problems
Authors: Erath Christoph , Schorr Robert
Published: May 2019

Many problems in electrical engineering or fluid mechanics can be
modeled by parabolic-elliptic interface problems,
where the domain for the exterior elliptic problem might be unbounded.
A possibility to solve this class of problems numerically is
the non-symmetric coupling of finite elements (FEM) and boundary elements (BEM)
analyzed in [H. Egger, C. Erath and R. Schorr,
On the nonsymmetric coupling method for parabolic-elliptic interface problems,
SIAM J. Numer. Anal. 56 2018, 6, 3510–3533].
If, for example, the interior problem represents a fluid,
this method is not appropriate
since FEM in general lacks conservation of numerical fluxes and in case of
convection dominance also stability.
A possible remedy to guarantee both is the use
of the vertex-centered finite volume method (FVM) with an
upwind stabilization option.
Thus, we propose a (non-symmetric) coupling of FVM and BEM for a semi-discretization of the
underlying problem. For the subsequent time discretization we introduce two
options: a variant
of the backward Euler method which allows us to develop an analysis under minimal regularity assumptions
and the classical backward Euler method.
We analyze both, the semi-discrete and the fully-discrete system, in terms of convergence
and error estimates. Some numerical examples illustrate the theoretical findings and
give some ideas for practical applications.
Versorgungssicherheit mit Strom: Empirische Evidenz auf Basis der Inferred-Valuation-Methode
Authors: Frondel Manuel , Sommer Stephan , Tomberg Lukas
Published: May 2019

Based on a survey among more than 5,000 German household heads, this article investigates their willingness to pay (WTP) for avoiding power outages usingContingent-Valuation-Methods (CVM). Alternatively, we ask respondents to estimate the WTP of a hypothetical household. ThisInferred-Valuation-Method (IVM) is an approach introduced to reduce the hypothetical bias of stated WTP. Our empirical results indicate that, relative to the CVM, the IVM yields inflated WTP values, casting doubt on the validity of the IVM.
Ausländische Direktinvestitionen in Deutschland – die große Angst vor China
Authors: Görg Holger
Published: May 2019

The current discussion in German policy circles suggests a strong scepticism towards foreign takeovers of German firms. This essay takes issue with this. It is firstly argued that Germany in actual fact receives relatively little inward investment. The essay then discusses the potential benefits from inward FDI which could also benefit the German economy. It then briefly reflects on the German policy initiatives which seem to be based on a fear of investment from China – though it is not clear at all what this fear is based on.
Sperm and seminal plasma RNAs: what roles do they play beyond fertilization?
Authors: Jodar Meritxell
Published: May 2019

The paternal contribution to the new individual is not just limited to half the diploid genome. Recent findings have shown that sperm delivers to the oocyte several components, including a complex population of RNAs, which may influence early embryo development and the long-term phenotype of the offspring. Although the majority of sperm RNAs may only represent spermatogenic leftovers with no further function, the male gamete provides a specific set of RNAs to the oocyte that is able to modulate gene expression in the preimplantation embryo. Those sperm transcripts include coding and non-coding RNAs that might either be translated by the oocyte machinery or directly regulate embryo gene expression at the transcriptional or post-transcriptional level. Interestingly, some sperm RNAs seem to be acquired during post-testicular maturation through active communication between sperm and epididymal and seminal exosomes released by the epididymis and the male accessory sex glands, respectively. Exosomes contained in the seminal plasma seem to not only interact with the spermatozoa but also with cells from the female reproductive tract, modulating their gene expression and influencing female immune response triggered by the semen. This review also considers the findings that indicate the role of semen RNAs in preimplantation embryo development and offspring phenotypes. In this regard, different studies supporting the hypothesis of paternal epigenetic inheritance of altered metabolic phenotypes associated with environmental exposures are discussed. Lastly, potential mechanisms that could explain the impact of semen RNAs to both early embryogenesis and paternal epigenetic inheritance are suggested.
Autoexplotación posmoderna y esclavitudes modernas. Reflexiones en torno a la subjetividad neoliberal
Authors: Polo Blanco Jorge
Published: May 2019

En el presente trabajo queremos mostrar la debilidad o, por ser más exactos, la parcialidad de ciertos análisis de la subjetividad neoliberal. Y lo haremos por cuanto desde ellos se suele contemplar el régimen laboral específico y propio de una minúscula parte de la población mundial como si fuera un régimen hegemónico y absolutamente global, cuando lo cierto es que ni siquiera en los países del Norte global es ampliamente mayoritario. Con ese gesto teórico, que además asume matices occidentalocéntricos, se oscurecen las formas de vida y los regímenes laborales de amplísimas geografías humanas del Sur (pero también del Norte) que en absoluto transcurren según los parámetros de dicha subjetividad. En ese sentido, son análisis que aciertan en su descripción de la subjetividad neoliberal, pero yerran sin embargo en el momento de universalizarla.
Sobre la polaridad simpatía-antipatía en la interpretación hipocrática de la phýsis humana
Authors: Henriquez Garrido Ruy J.
Published: May 2019

El propósito de este artículo es estudiar, en el contexto de la epistemología médica hipocrática, la importancia del par antitético simpatía-antipatía, como instrumento interpretativo de la phýsis humana. Con ello se pretende aportar comprensión a los métodos de inferencia desarrollados por la medicina antigua, de forma alternativa al método demostrativo.
GARDELLA, Mariana y JULIÁ, Victoria: El enigma de Cleobulina, Traducción de testimonios, acompañada de estudio preliminar, notas y apéndice, Prólogo de Walter O. Kohan, Teseo, Buenos Aires, 2018, 149p.
Authors: Vanag Dámaris Abigail
Published: May 2019

Recensión de la obra El enigma de Cleobulina de las especialistas en Filosofía Antigua, Mariana Gardella y Victoria Juliá. Publicada en el año 2018 por la editorial Teseo.
Rural Canada and the Canadian Innovation Agenda
Authors: Creasy Katelyn
Published: May 2019

There are a unique set of economic development challenges faced by rural Canadian communities. The launch of the federal government’s Canadian Innovation Agenda in 2016 provides an exciting vision for national economic growth and prosperity, but what does this mean for rural Canada? This paper examines both challenges and opportunities for rural Canada based on areas of focus in the Innovation Agenda and discussed the importance of including rural Canada in national innovation efforts.Keywords: innovation, rural, technology, partnerships, Innovation Agenda, population
Realigning Economic Development to Support Company Startup and Scale Up: A Burlington, Ontario Case Study
Authors: Cassidy Anita
Published: May 2019

In 2015 the City of Burlington developed a new 2015-2040 Strategic Plan: Grow Bold, which tasked Burlington Economic Development Corporation (BEDC) with supporting the start up and scale up of companies and making Burlington a start up destination. This article will outline the process that BEDC went through to better understand the local innovation ecosystem and the role that BEDC could play in supporting it. This process resulted in BEDC going from no role in supporting companies to start and grow to launching, TechPlace, Burlington’s new innovation Centre in 2017, which supported over 4,000 visitors in their entrepreneurial journey in year one of operations. 

Keywords: Innovation, Entrepreneurship, Startups, Job Creation, Startup Support, Innovation Centre
Research on the Construction Path of High-level Universities under the Background of “Double World-Class” in China: Taking Jiangsu Province as an Example
Authors: Liu Xuedong , Zhou Longjun , Chen Guoqing
Published: May 2019

Under the background of China’s “Double World-Class” construction, the paper takes high-level universities in Jiangsu Province as the research sample, and adopts a case study method to study the connotation of high-level universities, the effectiveness and problems of high-level university construction in Jiangsu Province. Based on this, the path selection of high-level university construction in Jiangsu Province is proposed, which is to optimize the education structure, clarify the school goals, strengthen the discipline construction, improve the education evaluation mechanism, enhance the level of education internationalization, enhance the ability of serving economic and social development, and promote Jiangsu Province marching from the “Great Province of Higher Education” toward “Strong Province of Higher Education”.
Experimental Study on the Construction and Hierarchical Teaching of “Pizza Type” Study Group in English in Elementary School
Authors: Niu Xuefeng
Published: May 2019

We take the problem of the intensification of English learning polarization in the senior students in the elementary school, and carry out the “Pizza-type” study group construction for the inefficient teaching phenomenon of grouping and despise cooperation in group learning. It was found that with the revelation: in practice, summed up the “Pizza learning group” construction method, summed up the “hierarchical” learning and teaching strategies, formation evaluation mechanism “Individual Three-Level, Cooperation in Three Dimensions”, and effectively alleviated the phenomenon of increased polarization.
Soledad en el adulto mayor: implicaciones para el profesional de enfermería
Authors: Chaparro Díaz Lorena , Carreño Moreno Sonia , Arias-Rojas Mauricio
Published: May 2019

Introducción: La soledad es una vivencia desfavorable, relacionada con la sensación de tristeza, que afecta la cotidianidad de la persona, el adulto mayor es más propenso a tener sentimientos de soledad debido a la falta de interacción con amigos, la enfermedad, la viudez o el deterioro cognitivo. El objetivo de este estudio fue integrar los hallazgos sobre la soledad en el adulto mayor e identificar los aspectos que influyen en la misma.  Materiales y Métodos: Se realizó una revisión sistemática de alcance integrativo. La búsqueda de información se realizó en 9 bases de datos, durante el periodo 2007 al 2018, se incluyeron en la revisión 36 estudios. Resultados: De acuerdo con la información encontrada emergieron 4 temas: características de la soledad en el adulto mayor, causas de la soledad, consecuencias de la soledad y factores que disminuyen los sentimientos de soledad. Discusión: La literatura indica que la soledad se relaciona principalmente con el aislamiento social, debido a la falta de interacción con otras personas y el desapego familiar lo que genera baja calidad de vida y riesgo de padecer enfermedades crónicas, es por esta situación que los profesionales de la salud deben prestar atención a una valoración holística del adulto mayor. Conclusiones: Los estudios muestran que existen varios aspectos que influyen en el proceso de soledad del adulto mayor, así como las principales acciones que puede realizar el profesional de la salud para intervenir este fenómeno.Como citar este artículo: Chaparro LD, Carreño SM, Arias-Rojas M. Soledad en el adulto mayor: implicaciones para el profesional de enfermería. Rev Cuid. 2019; 10(2): e633. http://dx.doi.org/10.15649/cuidarte.v10i2.633
O mestre subterrâneo: as afinidades eletivas entre Marcus Garvey e Kwame Nkrumah
Authors: Paiva Felipe
Published: May 2019

A característica mais marcante do político e ideólogo ganês Kwame Nkrumah (1909 - 1972) é seu pan-africanismo radical. O significante África tinha para ele o sentido de pátria-mãe, nação a ser construída e reconquistada. Este ímpeto pan-africano foi fruto de um amadurecimento visível em sua trajetória. Nela, o pensador jamaicano Marcus Garvey (1887 - 1940) desempenhou papel fundamental. Por meio de uma crítica da principal obra de Nkrumah relativa ao pan-africanismo, Africa Must Unite! (1963), abordamos neste artigo a relação intelectual entre ambos, procurando demonstrar tanto seus pontos de contato quanto seus atritos.
Exostosin 1/Exostosin 2–Associated Membranous Nephropathy
Authors: Sethi Sanjeev , Madden Benjamin J. , Debiec Hanna , Charlesworth M. Cristine , Gross LouAnn , Ravindran Aishwarya , Hummel Amber M. , Specks Ulrich , Fervenza Fernando C. , Ronco Pierre
Published: May 2019

Significance Statement

In approximately 70%–80% of cases of primary membranous nephropathy (MN), phospholipase A2 receptor (PLA2R)/Thrombospondin Type-1 Domain–Containing 7A (THSD7A) and anti-PLA2R/THSD7A antibodies form immune complexes along the glomerular basement membrane (GBM) that characterize the condition. In other cases of primary MN and all secondary MN, the target antigen is unknown. Using proteomics and immunohistochemistry, the authors detected two proteins, exostosin 1 (EXT1) and exostosin 2 (EXT2), in the GBM of PLA2R-negative MN. EXT1 and EXT2 were absent in all cases of PLA2R-associated MN and controls. Clinical and biopsy findings showed features of autoimmune disease, including membranous lupus nephritis, in 81% of the 26 EXT1/EXT2-associated MN cases the authors identified. These findings suggest that EXT1/EXT2-associated MN represents a distinct subtype of MN, most commonly associated with autoimmune diseases (secondary MN).

Background

In membranous nephropathy (MN), which is characterized by deposition of immune complexes along the glomerular basement membrane (GBM), phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain–containing 7A are target antigens in approximately 70% and 1%–5% of cases of primary MN, respectively. In other cases of primary MN and in secondary MN, the target antigens are unknown.

Methods

We studied 224 cases of biopsy-proven PLA2R-negative MN and 102 controls (including 47 cases of PLA2R-associated MN) in pilot and discovery cohorts. We also evaluated 48 cases of PLA2R-negative presumed primary MN and lupus MN in a validation cohort. We used laser microdissection and mass spectrometry to identify new antigens, which were localized by immunohistochemistry.

Results

Mass spectrometry detected exostosin 1 (EXT1) and exostosin 2 (EXT2) in 21 cases of PLA2R-negative MN, but not in PLA2R-associated MN and control cases. Immunohistochemistry staining revealed bright granular GBM staining for EXT1 and EXT2. Clinical and biopsy findings showed features of autoimmune disease, including lupus, in 80.7% of the 26 EXT1/EXT2-associated MN cases we identified. In the validation cohort, we confirmed that EXT1/EXT2 staining was detected in pure class 5 lupus nephritis (eight of 18 patients) and in presumed primary MN associated with signs of autoimmunity (three of 16 patients); only one of the 14 cases of mixed class 5 and 3/4 lupus nephritis was positive for EXT1/EXT2. Tests in seven patients with EXT1/EXT2-associated MN found no circulating anti-exostosin antibodies.

Conclusions

A subset of MN is associated with accumulation of EXT1 and EXT2 in the GBM. Autoimmune disease is common in this group of patients.
Carbon and nitrogen stable isotope analysis in harbor seal pup fur at CICESE v1
Authors: Carlos Herguera-García Juan , Heckel Gisela
Published: May 2019

In the Stable Isotope Laboratory at CICESE (Ensenada Center for Scientific Research and Graduate Education, Mexico) animal tissues (pup fur from Pacific harbor seals, Phoca vitulina richardii) were ground for isotopic determinations. Samples were stored in a dissecator until they were loaded into a Costech® Carrousel. Samples were combusted at high temperature (1000˚C) in a pure oxygen atmosphere in an elemental analyzer coupled to a Finnigan MAT Delta V Advantage continuous flow stable isotope mass spectrometer. Stable carbon and nitrogen ratios are expressed as δ13C or δ15N according to the following equation: δ13C or δ15N (‰) = [Rsample/Rstandard)–1]* 1000 (1) where R is 13C/ 12C or 15N/ 14N. Isotopic values of carbon and nitrogen are reported relative to Pee Dee Belemnite and atmospheric nitrogen standards, respectively. The accuracy of isotopic measurements was verified using secondary standard reference materials (Glutamic acid, a pure carbonate Merck and the laboratory internal references Lanugo for N, and CH94 for C).
Transformation v4
Authors: Yamur Akbiyik Rengin , Uysalcan Sevval
Published: May 2019

Transformation is a direct modification of the genotype of a cell from a different one by extracellular applications using recombinant DNA techniques. Transformation refers generally to the integration of exogenous DNA into the cell and its integration into the genome. Before starting the transformation process, the gene of interest is ligated with the plasmid vector via the ligase enzyme. This process is called ligation. Generally, nucleic acids or plasmids cannot enter into bacterial cells by themselves. The stimulatory effect is required for that purpose. This means that the cell membranes to be transformed must be pre-arranged. Bacteria that can contain free DNA are called competent bacteria. Some bacteria are highly competitive in normal growth conditions; but some must be treated with chemical or physical methods to gain competitive properties. Competent cells which are cells are generally stimulated with calcium chloride about chemically and the cell membranes are arranged such that the plasmid vector containing the gene of interest can harbor the vector. Some bacterial cells are lasting competent, however; most of them need to be influenced for being competent. There are two ways about this transformation process that; • Chemical Transformation • Electrical Transformation (Electroporation) In general, chemical transformation is used. In chemical way, some special chemicals are used to open the pores which are found in cell membrane. This is because, opening the pores represents the availability of being permeable. Most of the time, divalent ions like Ca++ are used with assistance of heat-shock.
Protein Expression v1
Authors: Yamur Akbiyik Rengin , Uysalcan Sevval
Published: May 2019

The protein expression is a process about synthesizing and modification for proteins in living organisms with using several laboratory techniques and devices. This technique is generally used for obtaining protein from the competent cell that is used for carrying plasmids that possess the protein that we want to express. Protein expression involves two general steps that; • Gene expression; which is continuum that converting DNA to the mRNA that can be translate into protein. • Protein manufacturing; which is translation process.
Calibration Protocol - Conversion of OD600 to Colony Forming Units (CFUs) v1
Authors: Tennant Richard , Rutten Paul
Published: May 2019

This procedure can be used to calibrate OD600 to colony forming unit (CFU) counts, which are directly relatable to the cell concentration of the culture, i.e. viable cell counts per mL. This protocol assumes that 1 bacterial cell will give rise to 1 colony. For the CFU protocol, you will need to count colonies for your two Positive Control (BBa_I20270) cultures and your two Negative Control (BBa_R0040) cultures.
YABANCI DİL OLARAK İNGİLİZCE ÖĞRENİMİNDE BASİTLEŞTİRİLMİŞ KİTAPLARIN KULLANIMINA ELEŞTİREL BİR BAKIŞ
Authors: ÇAKMAK Fidel
Published: May 2019

Okuma etkinliği hem ana dilde hem de yabancı bir dil öğrenmede önemli bir
yer tutar. Bireyler okuma aracılığıyla başka görüş, düşünce ve kültürel unsurları
öğrenir, onlarla etkileşimde bulunurlar. Bireylerin yabancı dil öğreniminde,
yabancı dilde okuma becerilerini geliştirmek amacıyla bazı uygulamalar
önerilir. Bunlardan biri, basitleştirilmiş kitaplardır. Bu çalışma, yabancı dil
öğreniminde okuma becerisinin arttırılması için yapılan basitleştirilmiş okuma
kitaplarının kullanımıyla ilgili önemli unsurları belirtmeyi ve bu tür
kitapların kullanımına eleştirel bir bakış sunmayı hedeflemektedir. Bu çalışma,
öncelikle basitleştirilmiş kitapların kullanımını tarihsel açıdan ele almış, faydaları
hakkında destekleyici ve karşıt görüşleri derlemiş, son olarak da
basitleştirilmiş kitaplardan yapısal örnekler ile dil öğrenimi açısından
sorgulama yapmıştır. Basitleştirilmiş kitaplar aracılığıyla, öğrencinin okuma
becerisi ve yabancı dil öğrenmesinin gelişmesi düşünülse de, bu tür kitapların
yabancı dil öğreniminde kullanımına temkinli bir şekilde yaklaşmak, kitapları
seçerken içerik olarak dil edinimi ve kültürel duruş olup olmadığını gözden
geçirmek gereklidir. Buna ek olarak, yabancı dil öğreniminde yapısal ve
bağlamsal olarak bir kazanım olup olmadığı sorgulanmalıdır. Sonuç olarak, basitleştirilmiş
olan edebi eserler yerine orijinallerin ve her seviyeye uygun farklı edebi
metin türlerinin yabancı dilde okuma becerisini geliştirmede kullanılması
önerilmektedir.
A civil law aspect of the dual-use goods regime
Authors: Shcherbakov M. G.
Published: May 2019

The paper analyzes the civil law regime of dual-use goods in the aspect of dual-use goods turnover. The author reveals the role of civil law rules as elements of the legal regime in the legal regulation of vertical and horizontal legal relations, as well as analyzes the process of transformation of civil law rules in the course of law enforcement. The author dwells on the main legal characteristics allowing to differentiate dual-use goods, namely: technical features, scope of application, availability of export control. In the paper, the author offers his own definition of the legal regime of dual-use goods. In addition, we identify such a feature of the regime of dual-use goods as dependance of the degree of turnover of dual-use goods upon external factors.

The author concludes that the functional purpose of civil law rules in the legal regime has changed.

In conclusion, a number of recommendations are proposed to improve efficiency of the legal regulation of foreign economic activity in the sphere of turnover of dual-use goods.
Darbelere Giden Süreçte Kamusal Rıza Üretiminde Basının Rolü: 27 Mayıs 1960 ve 15 Temmuz 2016’nın Karşılaştırmalı Analizi
Authors: ŞİMŞEK Serpil Seda
Published: May 2019

Türk siyasi hayatındaki darbelerin hazırlanış safhasında, gerçekleştirilmesinde ve sonrasındameşrulaştırılmasında asker, yargı, akademinin yanı sıra en önemli aktörlerden birisini de medyaoluşturmaktadır.27 Mayıs 1960 Türkiye Cumhuriyeti siyasi tarihindeki ilk darbe, 15 Temmuz 2016 isegünümüze kadar gerçekleşmiş son Darbe Girişimi özelliği taşımaktadır. Bu çalışmada, 27 Mayıs Darbesive 15 Temmuz Darbe Girişimi öncesinde, basında, özellikle “diktatörlük”, “otoriterlik”, “yolsuzluk”, “fikirve ifade hürriyetine baskı” kavramları etrafında oluşan darbeye kamusal rıza üretimi süreci ele alınmıştır.İlk olarak Antonio Gramsci’nin “hegemonya” ve Louis Althusser’in “devletin ideolojik aygıtları”na ilişkinteorileri kapsamında, medyanın darbe süreçlerindeki tutumu ile Türkiye’deki hegemonya arasındaki ilişkiaçıklanmaya çalışılmıştır. Ardından da bu iki örnek olayda kamusal rızanın nasıl üretildiği, “KamusalSenaryo Modeli”, Herbert Schiller ve Noam Chomsky’nin medya manipülasyonu analizleri çerçevesindeincelenmiştir. Merkez medya ve uluslararası medyanın bilerek veya bilmeyerek 15 Temmuz’a giden süreçte,27 Mayıs darbesi öncesine benzer şekilde sivil ve demokratik yönetime karşı bir askeri darbeye rıza üretimisürecinin parçası olduğu tespit edilmiştir.
Protestant Space-Continuity
Authors: Baku Eszter , Urbán Erzsébet , Vukoszávlyev Zorán
Published: May 2019

Intensive efforts started in the last decades to get to know the Central and Eastern European and the Hungarian church architecture. In this historically depressed period (1920/1945/1989), church buildings were important identity forming potencies in the life of the Protestant communities newly emerged by the rearrangement of country's borders. The modern architectural principles, the structural and liturgical questions gave opportunity for continuous experimentations in the examined period, which resulted a centralizing tendency between the two world wars. Analysing the Protestant space organization, it is verifiable that these centralizing tendencies with identification character did not pull out from the de-emphasizing church architecture in spite of the historical–political events of World War II. The primary importance of the study is the holistic examination of the Protestant church architecture of the 20th century. The study shows the Protestant Church activity of the period through the two most significant denominations —the Calvinist and the Lutheran church architecture—, thereby providing a typological approach.
Hydrocarbon Reservoir Evaluation: a case study of Tymot field at southwestern offshore Niger Delta Oil Province, Nigeria
Authors: Nwaezeapu Victor Cypren , Tom Izediunor U. , David Ede T. A. , Vivian Oguadinma O.
Published: May 2019

Abstract: Aim: This study presents the log analysis results of a log suite comprising gamma ray (GR), resistivity (LLD), neutron (PHIN), density (RHOB) logs and a 3D seismic interpretation of Tymot field located in the southwestern offshore of Niger delta. This study focuses essentially on reserves estimation of hydrocarbon bearing sands. Well data were used in the identification of reservoirs and determination of petrophysical parameters and hydrocarbon presence. Three horizons that corresponded to selected well tops were mapped after well-to-seismic tie. Structural depth maps were created from the mapped horizons. The structural style is dominated by widely spaced simple rollover anticline bounded by growth faults, and this includes down-to-basin faults, antithetic faults and synthetic faults. The petrophysical values – the porosity, net-to-gross, water saturation, hydrocarbon saturation that were calculated yielding  an average porosity value  of 0.23, water saturation of 0.32 and an average net-to-gross value of 0.62. Three horizons H1, H2 and H3 were mapped. The three horizons marked the tops of reservoir sands and provide the structures for hydrocarbon accumulation. Hydrocarbon in-place was estimated. The total hydrocarbon proven reserves for the mapped horizons H1, H2, and H3 were estimated to be 39.04MMBO of oil and 166.13BCF for sand E.
Outdoor Air Pollution and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
Authors: H. ELSHAHIDI Mohamed
Published: May 2019

Background: During the past 20 years, the prevalence of gestational diabetes mellitus (GDM) has increased by ∼10%-100% in several race/ethnicity groups. There is an association between ambient air pollution (AAP) and GDM. This study aimed to summarize the evidence about the association between AAP and GDM.
Methods: PubMed, Embase, Scopus, Web of Science and Cochrane Library were searched from inception till Oct 2017. Studies about the association between ambient air pollutants levels and GDM were included. Pooled effect estimates and their 95% confidence interval (CI) were calculated using R.
Results: Eight studies met the inclusion criteria. The odds of developing GDM upon exposure to CO (per 1 ppm), NO (per 1 ppb), NO2 (per 10 µg/m3), NOx (per 1 ppb), O3 (per 10 ppb), SO2 (per 10 ppb), PM10 (per 10 µg/m3) and PM2.5 (per 10 µg/m3) were 1.47 (95% CI 0.88-2.06), 1.04 (95% CI 1.03-1.06), 1 (95% CI 0.93-1.08), 1.02 (95% CI 1-1.04), 1.05 (95% CI 0.94-1.16), 1.39 (95% CI 1.04-1.73), 0.97 (95% CI 0.94-0.99) and 1.12 (95% CI 0.93-1.31), respectively.
Conclusion: The current literature showed evidence for an association between AAP and GDM. However, further well-designed studies are needed.
Zika Virus Infection, Basic and Clinical Aspects: A Review Article
Authors: NOORBAKHSH Farshid , ABDOLMOHAMMADI Kamal , FATAHI Yousef , DALILI Hossein , RASOOLINEJAD Mehrnaz , REZAEI Farshid , SALEHI-VAZIRI Mostafa , Zahra SHAFIEI-JANDAGHI Nazanin , Shamsi GOOSHKI Ehsan , ZAIM Morteza , NICKNAM Mohammad Hossein
Published: May 2019

Background: Zika virus infection has recently attracted the attention of medical community. While clinical manifestations of the infection in adult cases are not severe and disease is not associated with high mortality rates, Zika virus infection can have an impact on fetal development and lead to severe neurodevelopmental abnormalities.
Methods: To gain insight into different aspects of Zika virus infection, a comprehensive literature review was performed. With regard to epidemiology and geographical distribution of Zika virus infection, relevant information was extracted from CDC and WHO websites.
Results: In this review, we discuss different basic and clinical aspects of Zika virus infection including virology, epidemiology and pathogenesis of disease. Laboratory methods required for the diagnosis of disease together with ethical issues associated with Zika virus infection will also be discussed in detail.
Conclusion: Herein, we have tried to provide a multi-faceted view of Zika virus infection, with greater emphasis on disease status in Eastern Mediterranean Region.
Assessing Health Threatening Problems among Nursing or Midwifery Students during the Clinical Education Course in Turkey
Authors: ÖREN Besey , ZENGIN Neriman
Published: May 2019

Background: This study determined the occupational exposure and health problems experienced by nursing and midwifery students during their clinical internships.
Methods: The study population consisted of 1719 nursing and midwifery students studying at the health sciences faculties of six Turkish universities in 2016. Data were collected using a questionnaire prepared by researchers, namely Occupational Exposure and Health Problems in Clinical Environment Questionnaire, and the State-Trait Anxiety Scale. The data were analyzed using Mann Whitney U test, Kruskal Wallis variance analysis, and Spearman correlation analysis. Significance was accepted in a 95% confidence interval and a level of P<0.05.
Results: The students had a mean age of 20.86 yr (1.72), and 48.6% had midwifery and 51.4% had nursing major. More than 17.8% of the students were experienced occupational exposure during their clinical internships. Total score for students was 2.15 ±0.71. The scores of the students examined for exposure to hazards and verbal violence was 2.13 ± 1.17, for needle stick injury it was 2.10 ± 1.13. In addition, when the scores of the students' health problems were examined, insomnia 3.57 ± 1.22, low back pain 2.84 ± 1.29, shoulder or arm pain 2.68 ± 1.29 were determined statistically. There was a positive significant relationship between the mean clinical occupational hazardous exposure and health problems and state-trait anxiety scores (P<0.01).
Conclusion: Approximately one-fifth of the students were exposed to occupational hazardous at the hospital while they were on their clinical internship programs. Students rarely experience occupational exposure, but often suffer from insomnia, sometimes musculoskeletal pains (back, shoulder arm, neck), rarely have skin problems.
Effects of a Health Education Program on Fall Risk Prevention among the Urban Elderly: A Quasi-Experimental Study
Authors: KUHIRUNYARATN Piyathida , PRASOMRAK Prasert , JINDAWONG Bangonsri
Published: May 2019

Background: Elderly falls increase dramatically with age and are a leading cause of injury, carrying a risk of loss of independence and death. We studied the effects of a health education program on fall-risk prevention among urban elderly persons in the municipality of Khon Kaen, Thailand.
Methods: A quasi-experimental study was conducted in 2 communities. The calculated sample size was 216 individuals: 108 for intervention and 108 for control, all of whom were 60 or older, and registered at the Samlium Primary Care Unit (SPCU). The educational intervention was a fall risk intervention program by an elderly buddy. A structured questionnaire that incorporated questions from the Thai Fall Risk Assessment Tool (Thai-FRAT) was used to collect general and specific information. Data were analyzed using the independent sample t-test and c2, with P<0.05 being statistically significant.
Results: The response rate was 94.4%. More than half of the respondents were at risk of a fall. The prevalence of risk of a fall among the intervention group was slightly less than that for those within the control group [Intervention group=52.9% (95%CI: 42.85, 62.81, P<0.001); Control group=60.8% (95%CI: 50.59, 70.15, P=0.016)]. After 6 months of intervention, the balance impairment, medicine usage, and overall proportion with risk of fall were decreased. The difference between the intervention and control groups was statistically significant (P<0.05).
Conclusion: The provision of a health education program designed for fall risk prevention among the elderly would be a useful public health initiative.
The Characteristics of Human Resources and Related Research Activities among Basic Stem Cell Research Groups in China
Authors: WANG Sheng-Jun , LIU Li-Juan , JI Guang-Yue , ZHOU Xiao-Hua (Andrew) , JIANG Tian-Jiao , LU Mei-Hua , YU De-Lin , GUO Qiang , SUN Jin-Hai
Published: May 2019

Background: This study aimed to evaluate the characteristics of faculty and research activities of basic stem cell research groups in China.
Methods: A questionnaire was administered to persons who knew the information among 46 basic stem cell research groups in China. Multiple linear regression models and repeated-measures analyses of variance were used. Repeated-measures analyses of variance were used.
Results: Of the 46 groups, 39.1% did not have any faculty recruited from abroad from 2009 to 2013, 37.0% did not have any faculty with junior-level title, 34.8% had ≤25.0% faculty with either M.D. or Ph.D. degree. Papers published in SCI journals per faculty and having faculty recruited from abroad were positively associated with research funding per faculty. The groups with faculty recruited from abroad had significantly higher research funding per faculty over time compared with the group without faculty recruited from abroad. Repeated-measures analyses of variance showed the group with faculty recruited from abroad had significantly higher research funding per faculty over time compared with the group without faculty recruited from abroad.
Conclusion: To increase the development of basic stem cell research, some characteristics of human resources should be improved, and the groups should recruit more faculty with overseas experience.
The Frequency and Content of Prenatal Care Determine Birth Place: A Community Based Case-Control Study
Authors: ONER Can , CATAK Binali
Published: May 2019

Background: High-quality prenatal care services could decrease maternal-neonatal mortality and morbidities. The aim of this study was to compare institutional and unplanned home deliveries with regard to the use and content of prenatal care services.
Methods: The study was conducted in 2011 with two hundred and twenty-nine mothers with unplanned deliveries at home as study group and 458 mothers having institutional deliveries as controls living in Istanbul. The content of prenatal care was evaluated in accordance with the national ministry of health prenatal care management guidelines and the data was collected by a questionnaire with face to face interview.
Results: Women with unplanned deliveries at home use prenatal care services less frequently. Percentage of mothers that had home deliveries and did not use prenatal care services was 16.2% while this was only 3.4% in women having institutional deliveries (P=0.001). Moreover, all parameters of prenatal care were poor in content compared to women with institutional deliveries.
Conclusion: Adequate prenatal care services in terms of quantity and quality can promote institutional deliveries
Medical Imaging Technologists in Radiomics Era: An Alice in Wonderland Problem
Authors: ABDOLLAHI Hamid , SHIRI Isaac , HEYDARI Mohammad
Published: May 2019

The abstract not available.
Voltammetric Analysis of Cephalexin and Cefazoline in Pharmaceutical Formulation and Biological Samples
Authors: PERÇİN ÖZKORUCUKLU Sabriye , UKA Besnik , YILDIRIM BAŞTEMUR Gizem
Published: May 2019

In this study, the electrochemical behaviors of cephalexin
and cefazoline on disposable pencil graphite electrode were investigated in phosphate
buffer at pH of 4.5 to 6.0 by differential pulse voltammetry. Sample analysis
was performed in phosphate buffer at the optimum medium determined for each
sample. Validation parameters were studied to show the correctness,
sensitivity, and consistency of the method developed for the cephalosporins. It
was concluded that disposable pencil graphite electrode could be used
effectively in the determination of cephalosporins. The limits of detection (S/N=3)
were found to be 0.115 mM and 0.303 mM, for cephalexin and cefazoline,
respectively. The analysis of these compounds in pharmaceutical formulations
and biological samples was carried out at defined optimum conditions. The
recovery values were around 100%.
The influence of islamic ethical return, investment and firm value
Authors: Febri R.S. Wahyu , Sagena Basir , Prajawati Maretha Ika
Published: May 2019

Interest of investors in investing in the stock market is to get a rate of returnas an element of revenue. Given this background, this study was to determine the influence of ethical islamic return on investment and the value of the company, as well as the effect of the investment on firm value. The research was conducted on companies listed in the Jakarta Islamic Index for the period 2012-2015. The results showed an increase in income of non-kosher will lower interest of investors to invest, increase the amount of revenue non-kosher will lower the value of the company, an increase in the deviation of investment according to Islamic principles have a negative significant effect to company value, and increasing the amount of income halal through investments based on the principle -prinsip sharia will enhance shareholder value.
The effect of knowlege management and talent management on employee performance and the impact on competitive advantage (Survey at private colleges in Kulonprogo district, Yogyakarta)
Authors: Laras Titi , Kresnanto Nindyo Cahyo , Raharti Rini , Nurwiyanta Nurwiyanta , Wibowo Apriyanto Giri
Published: May 2019

This study aims to examine the effect of talent management and knowledge management on employee performance and the impact on performance of Private Colleges Employees in Kulonprogo, Yogyakarta, either partially or simultaneously. The research method used a survey with a questionnaire measured by a Likert Scale. The population is 104 Lecturers and Education Personnel at three active Private Colleges in Kulonprogo District. The data were analyzed by Lisrel 8.80 software. This study produced seven findings. First, Knowledge Management (X1) significantly affects on Employee Performance. Second, Talent Management (X2) significantly affects on Employee Performance (Y). Third, Knowledge Management (X1) and Talent Management (X2) simultaneously have a significant effect on Employee Performance (Y1). Fourth, Knowledge Management (X1) insignificantly affects on Competitive Advantage (Y2). Fifth, Talent Management (X2) insignificantly affects on Competitive Advantage (Y2). Sixth, Knowledge Management (X1) and Talent Management (X2) simultaneously have a positive and significant effect on Competitive Advantage (Y2). Seventh, Employee Performance (Y1) significantly affects on Competitive Advantage (Y2);
Healthy Birth Practice #5: Avoid Giving Birth on Your Back and Follow Your Body's Urge to Push
Authors: Curl Marilyn
Published: May 2019

Tradition, not evidence, continues to drive the management of the second stage of labor in most hospitals. This is an overview of current evidence associated with best practices for healthy outcomes for mothers and babies.
Conceptualizing Controlling Behaviors in Adolescent and Youth Intimate Partner Relationships
Authors: Taylor Alice Y. , Murphy-Graham Erin , Lauro Giovanna
Published: May 2019

Considerable evidence shows that adolescent intimate relationships influence the course of adult relationships, that is, whether relationship experiences are characterized by abuse or violence, or healthy, equitable dynamics. Controlling behaviors (CBs)—a phenomenon related to intimate partner violence (IPV)—are pervasive in adolescent intimate relationships, yet there is a lack of consensus on how to conceptualize them and subsequently, limited research which explores the role of CBs, including their role as warning signs for other forms of harm and abuse. As such, there are gaps in integrating CBs in policy and program interventions that could prevent IPV from the earliest stages. This article presents findings from in-depth qualitative research on adolescent relationship violence conducted in under studied settings of Brazil and Honduras. Adolescents described using or experiencing CBs in at least one form in 147 interviews with girls/young women and boys/young men aged 14–24 in rural and urban sites. Drawing from these empirical findings and conceptual and theoretical aspects from the literature, this article analyzes CBs in adolescent relationships and how they relate to IPV. By doing so, it seeks to offer a conceptual framework on CBs that could better inform policies and programs by being reflective of adolescent experiences, and ultimately more nuanced in promoting healthy adolescent relationships.