bluuebunny/crossref_metadata_2025 huggingface dataset:
Triglyceride Levels in the Blood after Anesthesia with Target-Controlled Infusion of Propofol for Brachial Plexus Surgeries in Adults: A Comparison between Conventional Propofol (LCT Propofol) and Newer Formulation of Propofol (MCT-LCT Propofol)
Authors: Ahemad Tamanna , Jayaram Prajna , K Pooja Rao , Tantry Thrivikrama Padur
Published: February 2025

Background: This study compares the impact of Medium chain-long chain triglyceride (MCT-LCT) Propofol and Long Chain Triglyceride Propofol on blood triglyceride (TG) levels in patients undergoing brachial plexus repair surgery. The study also investigates the effects of these drugs on postoperative recovery and overall patient well-being.
Methods: The study included fifty patients aged 18-60 scheduled for brachial plexus repair between July 2016 and July 2018. Patients were randomly assigned to two sets: Set LP received 1% LCT Propofol, while Set MP was given MCT-LCT Propofol using TCI-pumps. Blood samples for TG level determination were collected before anesthesia induction, after concluding the infusion, 4 hours after stopping infusion and on day 1 post surgery.
Results: Both sets showed a significant increase in TG levels above baseline, with a higher increase observed in the LCT Propofol set (P value = 0.014). After 4th hr of infusion, TG levels significantly decreased only in the MCT-LCT Propofol set (P value= 0.001), with levels lower than those in the LCT Propofol set (P value= 0.021).
Conclusion: Prolonged infusion of LCT and MCT-LCT Propofol (1%) resulted in elevated TG levels. However, the increase in TG levels was lower with MCT-LCT Propofol. No significant ill effects were observed.
Evaluating the Prognostic Value of Central Venous-to-Arterial PCO2 Difference in COVID-19 Patients Admitted to the Intensive Care Unit
Authors: Sedaghat Aliraza , Kermani Mahdieh Sharifzadeh , Yazdi Arash Peivandi , Khazaneha Mahdieh , Khadem-Rezaiyan Majid
Published: February 2025

Background: This study aimed to evaluate the relationship between the central venous-to-arterial PCO2 gap, serum lactate level, ScvO2, and prognosis of COVID-19 patients admitted to the intensive care unit. The study was performed in the intensive care unit of Imam Reza Hospital of Mashhad University of Medical Sciences.
Methods: The baseline sample and ABG sample were checked in terms of the PCO2 gap for 3 consecutive days. Lactate serum was also evaluated on the second day. Vital signs, oxygenation status, need for vasopressor, type of respiratory support, and calorie intake were recorded simultaneously. The length of stay in the intensive care unit, the duration of mechanical ventilation, and the patient’s discharge or death were also recorded.
Results: In this study, 147 COVID-19 patients were evaluated, of whom 115 patients died and 32 patients were discharged. The patients’ outcomes were assessed as the normal PCO2 gap (less than 6) and high gap (above 6). There were no significant differences between the high gap and mortality on the first day (p=0.833), second day (p> 0.99), and third day (p=0.82). PCo2 gap was not associated with ICU length of stay, duration of mechanical ventilation, SOFA, and APACHE score. The high gap patients had a significantly lower ScvO2 on the three days. Lactate serum was higher in the dead patients than in those discharged. The P/F ratio was significantly higher on the three days in the discharged patients than in the dead patients.
Conclusion: There is no relationship between the central venous-to-arterial PCO2 gap with the 28-day mortality rate in covid-19 patients.
Anesthetic Challenges and Strategies in a Child with Kawasaki Syndrome undergoing Surgical Intervention: A Case Report
Authors: Babajani Alireza , Arman Pegah , Moradi Ahmad , Torkhashvand Parasto Rahmati , Ghodarzi Yasin
Published: February 2025

A 26-month-old male patient presented with swelling in the right hemi-scrotum, diagnosed as a hydrocele and a 44 x 14 mm hernia displacing the right testicle. He had been hospitalized 12 days earlier due to prolonged fever, leading to concerns about Kawasaki syndrome. Prior to surgery, a cardiovascular consultation was performed, revealing no complications. The patient received treatment with clindamycin, ASA, prednisolone, and intravenous immunoglobulin. Admitted to Beheshti Hospital for surgery, his vital signs were stable. Anesthesia considerations were complicated by Kawasaki syndrome, but after consultation, general anesthesia was administered using a Laryngeal Mask Airway. The surgical procedure lasted an hour and fifteen minutes, during which basic monitoring was conducted. Post-surgery, the patient was transferred to recovery and later admitted to the pediatric department for two days, ultimately being discharged without complications.
Privacidade na coleta de dados pessoais sensíveis de pacientes:
Authors: De Carvalho Vieira Elba Lúcia , Alpoim de Santana Gustavo , Coutinho Mello Ricardo , Duarte de Miranda Zeny
Published: February 2025

A rápida expansão do uso da inteligência artificial tem trazido avanços em diversos aspectos da vida moderna. No entanto, é essencial considerar implicações relacionadas à privacidade dos dados pessoais de saúde. Este artigo visa abordar estas preocupações e analisar o atual cenário de uso da inteligência artificial na saúde pública brasileira. São discutidos impactos e desafios decorrentes dessa abordagem com base nas regulamentações existentes, como a Lei Geral de Proteção de Dados Pessoais (LGPD) no Brasil. A coleta de dados pessoais sensíveis é uma prática comum na área da saúde, com o objetivo de melhorar a prestação de serviços e promover a saúde da população. Porém, o uso da inteligência artificial levanta preocupações, sendo necessário preservar a privacidade dos seus titulares em consonância com a LGPD. Anonimização de dados pessoais sensíveis, consentimento informado dos pacientes e proteção dos dados são alguns desafios. A utilização da inteligência artificial na saúde pública requer o armazenamento e o processamento de grandes quantidades de dados. É essencial, portanto, implementar medidas de segurança robustas para proteger esses dados contra acesso não autorizado, violações e ataques cibernéticos. Torna-se premente, portanto, a implementação de medidas que assegurem não somente proteção ao compartilhamento indevido, como também ao acesso não autorizado. A pesquisa foi conduzida por meio de revisão sistemática de literatura, abrangendo artigos científicos, relatórios governamentais e regulamentações relacionadas à privacidade e proteção de dados. A revisão inclui estudos publicados nos últimos cinco anos, com foco em abordagens de inteligência artificial e suas implicações para a privacidade dos pacientes. Os resultados indicam que a coleta de dados pessoais sensíveis de saúde é uma prática comum. No entanto, o uso da inteligência artificial requer acesso a dados dos pacientes, como histórico médico, resultados de exames, informações sobre doenças, entre outros, e isso levanta preocupações sobre a privacidade. As instituições governamentais têm o dever de criar políticas públicas e fornecer os investimentos necessários para que a inteligência artificial melhore o processo de tomada de decisões em benefício da população. As instituições de saúde pública têm o desafio de implementar políticas, procedimentos e medidas técnicas, visando a privacidade na coleta e armazenamento de dados pessoais sensíveis, especialmente, no que se refere à anonimização, consentimento e proteção dos dados.
Response of Soil Applied Urea and Foliar Applied Nano Urea on the Growth, Yield and Quality of Kharif Sesame (Sesamum indicum) under the Central Plain Agro-climatic Zone of Punjab
Authors: Singh Surya Dev , Patil Sushant Sukumar , Jadhav Dhanshree Bharat , Birunagi S.M. , Karmakar K. , Saini N. , Hari Avani
Published: February 2025

Background: In context of oilseeds like Sesamum nitrogen is an important major or primary nutrient which is essential specifically for plant height, dry matter accumulation plant-1, development of pod and seed. Deficiency of Nitrogen in sesame results in lower vegetative growth, yield and dry matter partitioning. Along with this it also increase the photosynthetic rate and total chlorophyll content and application of nitrogen fertilizers through nano urea increases nitrogen use efficiency. Nano Urea is low cost technology and required in small quantities. Nano urea produces less hazardous effect on environment. It will also help in decreasing the amount of greenhouse gasses production and their release into the atmosphere. Even though the several research works are already available on effect of foliar spray in Sesame, scope of spray nano urea with different nitrogen levels in Sesame enabled us to take up this experiment. Methods: The present field experiment was carried out during Kharif season of 2022 at Agronomy Research Fields, School of Agriculture, Lovely Professional University, Phagwara, Punjab. Nitrogen is applied to sesame through soil as mineral nitrogen and foliar spray. The data pertaining to growth characteristics, yield characteristics, gross monetary returns and net monetary returns of sesame (kharif) was collected at regular interval in 2022-23 which was analyzed statistically in SPD (Split Plot Design) with 12 treatment combinations replicated thrice. Result: Significantly higher plant height (cm), no. of functional leaves plant-1, stem girth (cm) and dry matter accumulation (g plant -1) were registered with application F3 -100% RDN through soil application of mineral nitrogen to sesame over rest of treatments at 40 DAS, 60 DAS, 80 DAS and at harvest. Among the foliar application of nano-urea to sesame, treatment F4- 25% N recorded significantly higher plant height (cm), no. of functional leaves plant-1, stem girth (cm) and dry matter accumulation (g plant -1) over lower levels of treatments and found at with treatment F3-20% N at 40 DAS, 60 DAS, 80 DAS and at harvest.However at harvest higher number of dry capsules plant-1, number of seeds capsules-1, seed yield (q ha-1), straw yield (q ha-1) and oil content (%) were obtained by F3 -100% RDN through soil application of mineral nitrogen to sesame over all other treatments to sesame. Foliar application of F4 - 25% N and F3- 20% N to Sesame both being at par with each other and registered significantly higher number of dry capsules plant-1, number of seeds capsules-1, seed yield (q ha-1), straw yield (q ha-1) and oil content (%) over remaining levels of foliar applications of nano urea.
Exploring the Complementary Influence of an Oleuropein-Enriched Phytochemical Extract on Neuro-biochemistry, Behavior, and Histopathology in Aging and Depressed Male Rats
Authors: Tarbiat Shirin , Ergün Kübra , Aydoğdu Polat Refika , Ndengom Djomaleu Estelle Larissa , Filikci Kürşat
Published: February 2025

Aging correlates with neurodegenerative diseases such as depression, marked by neuro-biochemical changes triggering neuronal loss. Nutraceuticals exhibit antioxidant and neuroprotective properties and offer potential intervention. Our study examines the preventive effects of an olive leaf extract consisting of 20% pure oleuropein in an animal model of aging and depression. Aging in Wistar rats was induced by intraperitoneal injections of 150 mg of D-galactose/kg body weight for 6 weeks. The depression was caused by forced swimming. We examined Monoamine oxidase and acetylcholinesterase activities, histopathology of the brain, and the serum plasminogen activator inhibitor-1, superoxide dismutase, and monoaldehyde levels of all animal groups. Depressed and aged rats showed increased Monoamine oxidase, acetylcholinesterase, and plasminogen activator inhibitor-1 levels, and a decrease in superoxide dismutase levels. The administration of 200 mg of extract before depression or aging inductions, significantly reduced the Monoamine oxidase and acetylcholinesterase activities. Degeneration/necrosis was observed in neurons of all experimental animal groups. We demonstrate that the olive leaf extract with 20% pure oleuropein markedly maintained the neurotransmitter levels in the brain and enhanced the antioxidant defense system in depressed and aged animal models but was unable to yield behavioral benefits.
Online Sağlık Bilgisi Arama Davranışının Demografik Özelliklere Göre İncelenmesine Yönelik Bir Araştırma
Authors: Özişli Ömer
Published: February 2025

Bu çalışma ile online sağlık bilgisi arama davranışı ile demografik özellikler arasındaki ilişkinin tespit edilmesi amaçlanmaktadır. Araştırmada nicel yöntem kullanılmış olup veriler Sakarya ilinde 18 yaşını doldurmuş 407 bireyden kolayda örnekleme yöntemi ile toplanmıştır. Elde edilen verilerin analiz sonuçlarına göre katılımcıların online sağlık bilgisi arama davranışı orta düzeydedir. Çalışmada çıkan sonuçlara göre ilgili paydaşlara öneriler de bulunulmuştur.
SPTBN1 Heterozygous Mutation and Autism Spectrum Disorder: Is Paternal Inheritance Possible? A Case Report from Türkiye
Authors: Aydin Ayva Dilan , Tural Hesapçıoğlu Selma , Ceylan Mehmet
Published: February 2025

Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by impairments in social communication and interaction, restricted and repetitive behaviors, and ritualized behavioral patterns. It was reported 70-90% hereditary transmission in ASD. Single gene variants on chromosomes 1, 2, 3, 5, 7, 15, 16 and 22 have been reported to be associated with ASD. SPTBN1 encodes a βII-spectrin, which plays a critical role in the organization of the neuronal cytoskeleton. Variants in the SPTBN1 gene can therefore lead to various neurological diseases. Until now, the SPTBN1 gene located at the 2p16.2 locus has been shown to be associated with both maternal inheritance and de novo mutations. However, to the best of our knowledge, paternal inheritance has not yet been reported. In this study, we present a female autism case with a paternally inherited heterozygous missense mutation in the SPTBN1 gene. Additionally, this case represents the first autism case carrying an SPTBN1 mutation reported from Turkey.
Deux productions passées de la forêt guyanaise. L'essence de bois de rose et la gomme de balata
Authors: Bruleaux Anne-Marie
Published: February 2025

L'essence de bois de rose et la gomme balata ont joué un rôle important dans l'économie guyanaise au début du siècle. La nécessité de les récolter, l'évolution sociale du département et l'aspect spéculatif de leur commerce expliquent leur déclin. L'article ci-dessous retrace l'histoire de ces deux productions et mentionne la manière dont elles étaient obtenues.
Utilization of Windu Shrimp Shell Waste from Malaka-NTT for Chitosan Synthesis: Characterization Study and Application Potential
Authors: Kedang Yohana Ivana , Oktavianawati Ika , Tea Marselina Theresia Djue
Published: February 2025

Chitosan is a non-toxic and biodegradable polymer compound. Chitosan is widely applied in various industrial fields. This research uses shrimp shell waste from the Malaka-NTT as a chitin and chitosan production source. Chitosan synthesis consists of three steps, namely deproteination, demineralization and deacetylation. Chitosan characterization includes determining the degree of deacetylation (DD), determining functional groups using Fourier Transform Infra-Red (FTIR), and measuring crystallinity using X-ray diffraction (XRD). The DD results obtained were 83.7%. The FTIR spectra results of the chitosan samples in this study showed a typical peak at absorption of 1648 cm-1 indicating the vibration of the C=O group in NHCOCH3 (amide) I and absorption of 1589 cm-1 indicating the vibration of the N-H bending group (amide II). The results of the XRD diffractograms on the chitosan sample show an orthorhombic crystal structure with two typical peaks, namely at angles 2θ = 10.12° and 2θ = 19.87°. The DD results obtained in this study indicate that the chitosan produced has a fairly high amine group content, so chitosan as a biomaterial has the potential to be applied in various pharmaceutical and biomedical fields because it has environmentally friendly, biocompatible, and biodegradable properties. Therefore, based on the results of the DD calculation and the characterization of the FTIR and XRD instruments in this study, it shows that the synthesis of chitosan from the utilization of tiger shrimp shell waste from Malaka Regency-NTT has been successfully carried out.
Applications of Green Inhibitors of Sugarcane Bagasse and Garcinia Kola Fruit Pod for Mild Steel Natural Gas Pipeline Corrosion Inhibition in Acidic Medium
Authors: Jemine Teddy E. , Igbafe Sylvia , Adeniyi Adekunle Timisiriyu , IGBAFE Anselm Iuebego
Published: February 2025

This study examined the effectiveness of sugarcane bagasse (SCB) and garcinia kola fruit pod (GKFP) extracts as green corrosion inhibitors on mild steel. Extracts of SCB and GKFP were obtained using ethanol in a solvent extraction and characterized physiochemically and phytochemically. Using central composite design (CCD) approach in design expert version 12, process variables of extract concentrations of 0.025 - 0.075 g per liter, exposure durations of 4 - 6 days and temperatures of 50 - 80 °C were varied for the evaluation of the gravimetric corrosion tests. Phytochemical analyses revealed the presence of alkaloids, flavonoids, glycosides, saponin, steroids, phenols, terpenoids, tannin and anthraquinones. FTIR analyses of the SCB and GKFP extracts indicated functional groups of phenols, hydroxyl, alcohols, carbonyl, esters, alkyl halides, aldehydes and alkenes. The best of the observed CCD findings on inhibition efficiencies were 92.11 and 90.20 % on SCB and GKFP extracts respectively with process conditions of inhibitor concentrations of 0.025 and 0.075 g/L of SCB and GKFP extracts respectively for temperature of 50 °C and exposure time 5 days. However, on overall analyses based on varying inhibitor concentrations, temperature range and duration of exposure, the optimal inhibition performance was 62.04 % with SCB and 64.35 % with GKFP. The most effective inhibitor is GKFP which yielded a higher inhibition efficiency under same operating conditions. bioactive compound acts as antioxidants in providing a reducing environment of the acidic reaction by which hydrogen ion in donated in the cause of the reaction. The investigation between the absence and presence of phytochemicals coupled with the components in both extracts from FTIR analyses revealed the significant participation of the bioactive agents of on the mild steel corrosion inhibition in acidic medium.Keywords: Sugarcane bagasse, Garcinia kola fruit pod, corrosion inhibitors, acidic medium mild steel
Design and Implementation of Solar Cells as an Alternative Power Source for Pinisi Ships
Authors: Suardi Suardi , Maulana Mohammad Khafid , Ikhwani Rodlian Jamal , Pawara Muhammad Uswah , Mahmuddin Faisal , Tasrief Muhdar
Published: February 2025

The Pinisi is a traditional Indonesian ship recognized as a maritime cultural masterpiece and remains widely utilized, particularly in liveaboard tourism. The increasing demand for sustainable and innovative energy solutions in the tourism and maritime industries highlights the relevance of adopting solar cells as an alternative energy source for lighting on these ships. Solar cells, primarily made from silicon, efficiently convert solar radiation into electrical energy. This study evaluates the feasibility of using solar cells to power lighting systems on Pinisi ships operating in the Selayar Islands. Solar radiation data from NASA Surface Meteorology was utilized to estimate the optimal power output of solar modules. The analysis indicates that 10 solar cell modules can generate an energy output of 19.480 kWh, sufficient to meet the ship's lighting requirements. Configurations were optimized for different decks, ensuring efficient energy distribution while maintaining sustainability. The findings demonstrate that implementing solar cells on Pinisi ships not only fulfills their energy needs but also supports the maritime tourism industry by providing an eco-friendly and innovative energy solution. This approach contributes to the preservation of maritime heritage while addressing contemporary environmental challenges.Keywords: Pinisi ship, solar cells, energy conversion, maritime tourism innovation
Design of Waste Management in Nuclear Medicine Isolation Room of Dr. Sardjito Central General Hospital
Authors: Efendi Ahmad Mudzakir , Mondjo Mondjo , Purwanti Eli
Published: February 2025

The purpose of isolation room is to prevent radioactive contamination from the patient's metabolic processes. Because of that the radiation dose around the room and working area need to be limited. So that the value of the dose limits are not exceeded, the work area could be divided according to Perka Bapeten number 17 of 2012 Article 35. The working area can be divided into two parts: control region and supervision region. According to Perka Bapeten number 4 of 2013 Dose Limit Value (DLV) received in the control region has the potential to exceed 3/10 radiation workers DLV and the dose received in the supervision region has the potential of less than 3/10 radiation workers DLV and exceed people DLV. The isolation room is belong in the control region. The liquid waste from the isolation room is accommodated in the multi tank to delay it before being released to wastewater treatment plant. The isolation room needs ventilation using filters to prevent contamination via air circulation. The position of the preparation and radiopharmaceutical room and the waste storage room which is in the control region must be adjacent to the isolation room.Keywords: Isolation Room, Radioactive, Control Region, Supervision Region, DLV.
THE INFLUENCE OF PROFITABILITY, LEVERAGE AND ACTIVITY ON THE SHARE PRICE WITH LIQUIDITY RATIO AS MODERATING VARIABLE
Authors: Kawijaya Jovita Zefanya Stephanie , Simorangkir Enda Noviyanti , Tarigan Aremi Evanta
Published: February 2025

ABSTRACTStock prices can be predicted using financial ratios. Researchers in this study only examined Profitability, Activity, Leverage, and Liquidity ratios. This research examines and analyzes stock prices on companies on the ISE or Indonesia Stock Exchange with Tbk status, 2019 – 2022. The variables tested are profitability, activity, and leverage, using liquidity as a moderating variable. The quantity intended selection was relating to using a purposive sampling method with historical data acquired from IDX website, www.idx.co.id. The data analysis process was related to using PLS Algorithm calculations on SmartPLS to exercise the hypothesis. The research results cause that profitability and activity have a significant bring on stock prices, while leverage is not significant result on share prices. Apart from that, the moderating variable of liquidity only has a significant bring on share prices as an independent variable because, with its position as a moderating variable, liquidity does not significantly result to the profitability, activity, and leverage variables. The effect of research provides sufficient insight that share prices generally have a greater influence on investor behavior.Keywords: Profitability; Activity; Leverage; Share Price; Liquidity
ABSTRAKHarga saham dapat diprediksi dengan menggunakan rasio keuangan. Peneliti dalam penelitian ini hanya meneliti rasio Profitabilitas, Aktivitas, Leverage, dan Likuiditas. Penelitian ini menguji dan menganalisis harga saham pada perusahaan di BEI atau Bursa Efek Indonesia yang berstatus Tbk, tahun 2019 – 2022. Variabel yang diuji adalah profitabilitas, aktivitas, dan leverage, dengan menggunakan likuiditas sebagai variabel moderasi. Pemilihan kuantitas yang dimaksud adalah dengan menggunakan metode purposive sampling dengan data historis diperoleh dari website IDX, www.idx.co.id. Proses analisis data terkait dengan penggunaan perhitungan Algoritma PLS pada SmartPLS untuk menguji hipotesis. Hasil penelitian menunjukkan bahwa profitabilitas dan aktivitas berpengaruh signifikan terhadap harga saham, sedangkan leverage tidak berpengaruh signifikan terhadap harga saham. Selain itu, variabel moderasi likuiditas hanya mempunyai pengaruh yang signifikan terhadap harga saham sebagai variabel independen karena dengan posisinya sebagai variabel moderasi, likuiditas tidak berpengaruh signifikan terhadap variabel profitabilitas, aktivitas, dan leverage. Pengaruh penelitian memberikan wawasan yang cukup bahwa harga saham secara umum mempunyai pengaruh yang lebih besar terhadap perilaku investor..Kata Kunci: Profitabilitas; Aktivitas; Leverage; Harga Saham; Likuiditas
Potensi Ekonomi Prospektif Kobalt (Co) Sebagai Mineral Ikutan dalam Penambangan Bijih Nikel di Kecamatan Langgikima Kabupaten Konawe Utara
Authors: Nafiu Wd Rizky Awaliah , Anshari Erwin , Passaly Thegar Aditya
Published: February 2025

Penelitian ini mengkaji potensi nilai ekonomi kobalt sebagai mineral ikutan pada pertambangan bijih nikel di Kecamatan Langgikima, Kabupaten Konawe Utara, Provinsi Sulawesi Tenggara. Kabupaten ini dikenal sebagai salah satu penghasil bijih nikel terbesar di Indonesia dengan kobalt (Co) yang ditemukan sebagai mineral ikuran yang sering ditemukan bersama bijih nikel. Kobalt memiliki nilai strategis dalam industri modern, khususnya baterai lithium-ion, yang penting dalam kendaraan listrik dan perangkat elektronik. Penelitian ini menggunakan pendekatan kuantitatif dengan mengumpulkan data sekunder dari perusahaan pertambangan dan literatur terkait. Analisis dilakukan untuk memperkirakan kandungan kobalt dalam sumber daya bijih nikel yang teridentifikasi dan menghitung potensi nilai ekonominya berdasarkan harga pasar kobalt saat ini. Analisis dilakukan untuk memperkirakan kandungan kobalt dalam sumber daya bijih nikel yang teridentifikasi dan menghitung potensi nilai ekonominya berdasarkan harga pasar kobalt saat ini. Hasil penelitian menunjukkan bahwa di lokasi penelitian mempunyai potensi kandungan kobalt  dengan perkiraan sumber daya sebesar 643.580,85 ton dan cadangan diperkirakan sebesar 382.360 ton. Analisis prospektif nilai ekonomi kobalt sebagai mineral ikutan dari sumber daya dan cadangan menunjukkan potensi ekonomi dengan nilai masing-masing sekitar 16,8 miliar USD dan 10,01 miliar USD. Penelitian ini juga memberikan landasan untuk mengembangkan strategi pengelolaan yang berkelanjutan dan optimal atas potensi kobalt sebagai aset mineral ikutan dalam industri pertambangan bijih nikel.
Degraded Forest Evaluation Using Vegetation Indices at Bandealit Resort, Meru Betiri National Park
Authors: Mulyadi Budi Putra , Sulistiyowati Hari , Wimbaningrum Retno
Published: February 2025

The forest degradation and deforestation was widely occurred in Indonesia and Meru Betiri National Park is one of the area with illegal loggings threats. Bandealit Resort as one of the resort in Meru Betiri National Park was reported as the area with high activity of illegal loggings specifically in 2020. Based on this information, this research study aims to evaluate the degraded level of the forests using Normalized Difference Vegetation Index and Enhanced Vegetation Index (NDVI and EVI) so it can be managed and evaluated in the future. This research use direct and indirect observation methods in three areas with different damage levels. Direct observation was done by counting the number of species and the stands trees, while the indirect observation was analyzing the Landsat 8 Imagery in 2020, 2021 and 2022. The results showed that the A area had the lowest density with only 45 remaining trees than two others with more than 150 trees. The greenness levels imply the quality level of tree stand density, as higher the tree stand density, the higher the greenness. NDVI and EVI showed that A area had the range from low greenness (sparse density) to high greenness (medium density) than two others area had the higher greenness and densities.
Kajian Kualitatif Berbasis NVivo Dalam Mata Kuliah Perubahan Iklim
Authors: Safitri Aida , Susanti Nova , Nurhatmi Jules
Published: February 2025

Penelitian ini bertujuan untuk menganalisis hubungan antara motivasi siswa dan prestasi belajar pada materi perubahan iklim dengan menggunakan pendekatan Technology-Based Learning Assessment (TBLA) berbasis perangkat lunak NVivo. Melalui pendekatan kualitatif, data dikumpulkan dari partisipasi siswa dalam kegiatan pembelajaran, baik berupa interaksi di kelas, diskusi kelompok, maupun tugas individu yang terkait dengan topik perubahan iklim. Data tersebut kemudian dianalisis menggunakan NVivo untuk mengidentifikasi pola-pola motivasi siswa dan hubungannya dengan hasil belajar mereka. Hasil penelitian menunjukkan bahwa motivasi yang tinggi, baik intrinsik maupun ekstrinsik, memiliki pengaruh positif terhadap prestasi belajar siswa dalam memahami materi perubahan iklim. Siswa yang termotivasi lebih aktif berpartisipasi dalam pembelajaran dan menunjukkan pemahaman yang lebih baik terhadap topik tersebut. Penelitian ini juga menawarkan kontribusi penting dalam pengembangan metode penilaian berbasis teknologi, yang dapat digunakan untuk mengukur secara lebih akurat faktor-faktor yang memengaruhi hasil belajar. Selain itu, penelitian ini memperkaya pendekatan kurikulum sains, yang semakin terintegrasi dengan teknologi digital, untuk mendukung pembelajaran yang lebih efektif dan relevan dengan tuntutan zaman. Dengan demikian, hasil penelitian ini dapat memberikan wawasan yang berguna bagi pengembangan kurikulum dan strategi pembelajaran di era digital.
Utilization of Tempe as a Base Material in the Study of Electromagnetic Wave Properties in the ELF (Extremely Low Frequency) Range
Authors: Pravitasari Arinda , Wati Eka Rinda , Amanda Via , Agustin Adelia , Puji Lestari Adelia Andini , Sudarti Sudarti , Kurnia Saidah Intan
Published: February 2025

Electromagnetic waves are transverse waves consisting of electric and magnetic fields that are perpendicular to each other and can propagate without a medium. The sub-spectrum of electromagnetic waves with a frequency range of 0 to 300 Hz is known as Extremely Low Frequency (ELF) electromagnetic waves. This experiment aims to demonstrate the effects of ELF magnetic field radiation on the ripening of food materials. The control and experimental groups in this study involved test materials, including 1 kg of cassava tape, 1 kg of glutinous rice tape, and 1 kg of tempeh. Each test material was divided into the control and experimental groups, then arranged into 10 samples, each weighing 100 grams, and wrapped in ziplock plastic bags. Each group was left for two days of fermentation, with the distinguishing factor being that the experimental group was exposed to ELF magnetic fields beforehand. Observations revealed differences in physical conditions such as texture, aroma, taste, and color between the control and experimental groups. Specifically, the physical conditions texture, aroma, and color differed between the two groups.
Bioactivity of Endophytic Fungal Extract Isolated from Purun (Eleocharis dulcis (Burm.f.) Trin. ex Hensch)
Authors: Oktiansyah Rian , Pratiwi Mardiyah , Kharisma Sully Pudja , Fauzan Ahmad Rizki , Utami Riza , Amelia Dea , Noviyanto Noviyanto , Nasution Sakinah Salman Ahmad
Published: February 2025

The study investigates the bioactivity of endophytic fungi isolated from Eleocharis dulcis (Burm.f.) Trin. ex Hensch., focusing on their potential as alternative sources of bioactive compounds. E. dulcis, a plant commonly found in wetland ecosystems, has traditionally been used for its medicinal properties. However, the massive extraction of the plant may lead to ecological imbalance, prompting the exploration of endophytic fungi as a sustainable alternative. The objective of this research is to isolate, identify, and evaluate the antimicrobial and antioxidant properties of endophytic fungi from Eleocharis dulcis. Endophytic fungi were isolated aseptically, followed by morphological identification. Antioxidant and antimicrobial assays were conducted to assess the bioactivity of the fungal extracts. Antioxidant activity was evaluated using the DPPH method, while antibacterial activity was assessed using the disc paper diffusion method. The results revealed that several isolates (from leaves: LP1 � LP6, from root: RP1 � RP3) exhibited significant antimicrobial activity against Escherichia coli and Staphylococcus aureus, with Penicillium spp. and Cladosporium spp. showing the highest levels of bioactivity. Additionally, all fungal isolates demonstrated very strong antioxidant activity, with most achieving an IC50 below 20 �g/mL. In conclusion, the findings suggest that endophytic fungi from E. dulcis represent a valuable source of bioactive compounds with potential applications in pharmaceuticals. Further research is required to isolate and characterize the active compounds, as well as to evaluate their efficacy through in vivo studies
Peluang Reformulasi Penegakan Hukum Terhadap Tindak Pidana Praktek Monopoli dan Persaingan Usaha Tidak Sehat
Authors: Samudra Lintang Akbar
Published: February 2025

Berdasarkan Undang-undang (UU) Nomor 5 Tahun 1999 tentang Larangan Praktek Monopoli dan Persaingan Usaha Tidak Sehat telah diatur bagaimana persaingan usaha yang sehat. Dalam perkembangannya antara tahun 2021 – 2022 terdapat persaingan usaha yang tidak sehat terhadap minyak goreng berupa membatasi peredaran dan atau penjualan barang dan atau jasa pada pasar bersangkutan sebagaimana sebagaimana Putusan Perkara Nomor: 15/KPPU-I/2022. Terdapat permasalahan yang mendasar pada undang-undang a quo khususnya terhadap batasan kewenangan Komisi Pengawas Persaingan Usaha (KPPU) untuk melakukan penyelidikan dugaan praktek monopoli dan/atau persaingan usaha tidak sehat serta ketidakjelasan ketentuan jenis-jenis tindak pidana yang dapat diberikan kepada pelaku usaha ketika hukum administrasi atau perdata kurang efektif. Berdasarkan latar belakang hal  tersebut,  pada  penelitian  ini  kemudian  menghasilkan  2  (dua)  rumusan masalah, yaitu bagaimana implikasi penegakan hukum pidana berdasarkan Undang-undang Nomor 5 tahun 1999 tentang Larangan Praktek Monopol dan Persaingan Usaha Tidak Sehat, dan bagaimana aturan hukum yang ideal demi mewujudkan keadilan dalam penegakan hukum pidana persaingan usaha. Penelitian ini berjenis penelitian yuridis-normatif dengan  mengkaji data-data  sekunder  melalui  studi  kepustakaan. Hasil penelitian menunjukkan bahwa, Undang-undang Nomor 5 tahun 1999 tentang Larangan Praktek Monopol dan Persaingan Usaha Tidak Sehat terbatas mengatur ketentuan pidana jika pelaku usaha tidak melaksanakan Putusan Komisi Pengawas Persaingan Usaha (KPPU) sebagaimana Pasal 44 ayat (4), lebih lanjut tidak terdapat ketentuan siapakah yang berhak melakukan penyelidikan atas pelanggaran tindak pidana pada Pasal 48 dan Pasal 49, serta terhadap Komisi Pengawas Persaingan Usaha (KPPU) tidak memiliki norma pengaturan untuk melakukan penyelidikan. Oleh karena itu dirasa perlu untuk dilakukan pembaharuan hukum Undang-undang Nomor 5 tahun 1999 tentang Larangan Praktek Monopol dan Persaingan Usaha Tidak Sehat yang mengakomodir keseluruhan permasalahan tersebut maupun mempertimbangkan aspek pertanggungjawaban pidana terhadap korporasi.
Mastery-Based Testing in Linear Algebra: An Entry Point to Alternative Grading
Authors: Swanson Rebecca , Bingham Aram , Sanders Megan , Moulton Carter
Published: February 2025

An increasing number of university faculty have become interested in alternative grading systems in recent years. While there is a growing body of research on such grading systems, implementation can be a challenge for instructors. Mastery-based testing is a grading system in which students learn from feedback and have multiple attempts to demonstrate proficiency in a written exam setting without penalty. Student exam scores are determined by the number of course learning outcomes successfully completed by the end of the course. Given that all other aspects of the course are left in place, this model can serve as a relatively simple entry point into alternative grading. We implemented mastery-based testing in three sections of a 16-week high-enrollment university linear algebra course and gathered data on student perceptions of and performance in this revised course. In this paper, we report on students’ descriptions of the benefits and drawbacks of this system, their beliefs about final grades in this course compared to other courses, and their self-reported study habits.
Life cycle assessment of active spring frost protection methods in viticulture in the Loire Valley and Champagne French regions
Authors: Baillet Vincent , Pauthier Basile , Payen Antoine , Naviaux Pierre , Symoneaux Ronan , Chassaing Thomas , Renaud-Gentié Christel
Published: February 2025

Spring frosts have been identified as a significant threat to the wine sector, particularly in regions with early vine budbreak. The severity of frost damage varies depending on local climatic conditions, topography and other contextual factors. To protect vines, growers employ a range of techniques designed to increase the temperature around the buds. As climate change increases frost risk, several Active Spring Frost Protection Methods (ASFPMs) have emerged, often associated with high resource consumption and considerable labour demands. To support decision-making, Life Cycle Assessments (LCA) have been conducted on a comprehensive range of ASFPMs applied in the Loire Valley and Champagne French regions. These two regions differ in terms of ASFPM use, field management and local climatic conditions. Environmental assessments were performed using a context-specific LCA framework, taking into account context-specific factors such as application and climate variables. In total, six technologies of ASFPMs were compared: antifrost candles, wind machines, heaters, heating cables, sprinklers and winter cover. The Impact world + characterisation methodology was employed to calculate the following environmental indicators: Climate change, Fossil and nuclear energy use, Mineral resources use, Water scarcity, Terrestrial acidification, Human toxicity and Land occupation. Overall, wind machines and sprinklers showed better environmental performances than other technologies in both regions. However, sprinklers had the largest impact on the water scarcity indicator. Antifrost candles and fuel-fired heaters had the largest environmental impacts in the Loire Valley and Champagne regions, respectively. A sensitivity analysis based on the number of frost hours occurring during spring showed that instant ASFPMs, such as heaters and antifrost candles, exhibited greater variability due to their high direct emissions during use. In contrast, ASFPMs requiring fixed infrastructure, such as wind machines, sprinklers, winter covers and heating cables, showed less variability due to their lower fuel consumption per hectare. The integration of context-specific factors proved essential in this comparison, as the environmental ranking of ASFPMs was influenced by the number of frost hours in each region. For future research endeavours, it would be relevant to include ASFPM in the overall environmental assessment of the viticulture stage to determine its contribution and increase the robustness of the environmental performance of the viticulture stage.
Exercise-induced anaphylaxis
Authors:   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation, Pampura A.N. ,   Morozov Children’s City Clinical Hospital, Moscow, Russian Federation, Esakova N.V. ,   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation, Filippova E.A. ,   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: February 2025

Exercise-induced anaphylaxis (EIA) is a systemic and potentially fatal hypersensitivity reaction triggered by physical activity of different intensity. Regarding the diagnosis and management of patients with an immediate and acute episode of EIA, it is necessary to consider the basic details of the patient’s medical history, which may play a key role in the diagnostic process. However, diagnosis verification presents some difficulties. Data on the mechanism of pathogenesis are very limited, as are laboratory tests; in addition, there are no generally accepted protocols for provocation tests, which are the only reliable way to confirm the diagnosis. These features determine the relevance of investigating this nosology in the management of patients with acute allergic systemic reactions. This article presents current information on the prevalence, pathogenesis, principles of diagnosis and treatment of EIA and describes a clinical case of this condition.
Key words: anaphylaxis, physical activity, hypersensitivity reaction, diagnosis, ISAC, children
Evaluation of nutritional value of gluten-free cereal bars based on expanded grains in the nutrition for children over three years of age
Authors:   Research Institute of Food Concentrate Industry and Special Food Technology, Branch of the Federal Research Centre of Nutrition, Biotechnology and Food Safety, Izmaylovo District, Moscow Region, Russian Federation, Urubkov S.A. ,   Russian Biotechnology University (ROSBIOTECH), Moscow, Russian Federation, Budova A.V. ,   Research Institute of Food Concentrate Industry and Special Food Technology, Branch of the Federal Research Centre of Nutrition, Biotechnology and Food Safety, Izmaylovo District, Moscow Region, Russian Federation, Smirnov S.O. ,   Research Institute of Food Concentrate Industry and Special Food Technology, Branch of the Federal Research Centre of Nutrition, Biotechnology and Food Safety, Izmaylovo District, Moscow Region, Russian Federation
Published: February 2025

Objective. To study the nutrient composition of samples of gluten-free cereal bars based on expanded grains and to evaluate their nutritional value on the example of their consumption by children over three years of age.
Materials and methods. The objects of the study were two samples of cereal bars based on expanded grains with fruit and berry components. Standard methods were used to estimate the content of protein, fats and carbohydrates, including monoand disaccharides, and dietary fiber.
Results. Quantitative characteristics of the essential nutrients in samples of gluten-free cereal bars was obtained. Carbohydrates on average accounted for 83.5% of the total essential nutrients, with an average of 55% represented by starch. The total amount of mono- and disaccharides did not exceed 19%, and the ratio of glucose to fructose was approximately 2:1. The average total content of dietary fiber in the studied samples of bars was 11%, and the proportion of soluble fiber was 9.4%.
Conclusion. High contents of dietary fiber and plant protein determine a high nutritional value of the developed product. The results of calculating the fulfillment of recommended dietary intake for children indicate the prospective use of the developed gluten-free cereal bar as a functional food product.
Key words: gluten-free foods, children over three years of age, cereal bars, nutritional value, carbohydrate profile, expanded grains
Problems of adaptation of young orphans in foster families
Authors:   Ivanovo State Medical University, Ivanovo, Russian Federation, Antysheva E.N. , Dubrovskaya M.I. ,   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation, Kocherova O.Yu. ,   V.N.Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federation, Chubarovskiy V.V. ,   F.F.Erisman Federal Scientific Center of Hygiene, Mytishchi, Moscow Region, Russian Federation, Filkina O.M. ,   V.N.Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federation, Smirnova S.V. ,   Ivanovo State Medical University, Ivanovo, Russian Federation
Published: February 2025

Objective. To identify biological and psychosocial factors affecting the adaptation of young orphans during the first year of living in foster families.
Patients and methods. The health status of 90 young orphans during the first year of living in foster families and 90 peers raised in biological families, as well as the psychological characteristics of their mothers, were assessed. The study included collection and analysis of medical records, evaluation of morbidity, physical and neuropsychological development, emotional status of children, and attachment type.
Results. After 1 year of living in foster families, the frequency of iron-deficiency anemia, rickets, hypotrophy, scabies and pediculosis decreased in orphans, but there was still a delay in neuropsychological development, mainly due to comprehensible and active speech, sensorics; negative emotions – fear, anger; low level of cognitive activity, social activity and positive emotions. The attachment of orphans to foster mothers was formed: secure (38.5%), affective (21.5%), indifferent (20%), symbiotic (13.9%), disorganized (6.1%). The motives for adopting an orphan into a foster family were found to be harmonious (23.1%), altruistic (30.8%), egocentric (21.5%), normative (21.5%), and material (3.1%). Three types of adaptation course were identified: favorable (32.3%), conditionally favorable (32.3%), and unfavorable (35.4%). Risk factors for unfavorable adaptation of children in foster families were the age of a child at the time of placement (older than 1 year in combination with a pronounced delay in neuropsychological development), previous negative experience of parental care, non-harmonious motives for creating a foster family, personal characteristics of mothers, and insufficient time devoted by foster mothers to orphans.
Conclusions. Adaptation of orphans in foster families should be supervised by medical and psychological support programs developed according to the assessment of the child’s somatic and neuropsychological health, motives for adopting him or her into a foster family, considering the personal characteristics of foster mothers and risk factors for adverse adaptation.
Key words: foster family, biological family, adaptation, orphans, foster mother, children, early childhood, upbringing, attachment
A SOFTWARE SOLUTION FOR REAL-TIME COLLECTION AND PROCESSING OF MEDICAL DATA FOR EPILEPSY PATIENTS
Authors: Kopp Andrii , Liutenko Iryna , Yamburenko Viktor , Pashniev Andrii
Published: February 2025

The rapid development of computer technologies has significantly impacted various sectors, including healthcare. The ability to collect, process, and visualize medical data in real time is becoming increasingly important, especially for managing chronic conditions such as epilepsy. This paper presents a web-based application designed for real-time monitoring of health indicators, enabling healthcare professionals to track patient data efficiently. The system automates the process of collecting data from fitness trackers, transmitting it via a mobile device to a server, and visualizing it in a web application. Its architecture employs a thin-client model with Node.js for backend logic and React.js for the user interface, ensuring scalability and responsiveness. Key features include real-time data visualization, historical trend analysis, and the ability to export health metrics for further examination. The system architecture follows a modular approach, with a clear separation of concerns between the client-side, server-side, and database components. MongoDB is used as the database provider, offering flexibility in handling large volumes of health data. The system underwent extensive testing in two stages. During the first stage, real-world data collection demonstrated an average data transmission time of less than 112 ms, ensuring compliance with real-time requirements. In the second stage, stress testing with up to 100 simultaneous users showed an average server response time of 145.8 ms and a 95th percentile response time of 167.1 ms. These results confirm the system’s robustness and suitability for deployment in medical facilities. Future work aims to enhance the system by incorporating advanced real-time alert mechanisms and additional health metrics, such as oxygen saturation and activity levels, to provide comprehensive monitoring. The presented solution showcases the potential of integrating modern web technologies into healthcare, contributing to improved patient outcomes and more efficient workflows for medical professionals.