bluuebunny/crossref_metadata_2025 huggingface dataset:
Cauda equina syndrome
Authors: Hoeritzauer Ingrid , Paterson Mhairi , Jamjoom Aimun A. B. , Srikandarajah Nisaharan , Soleiman Hamzah , Poon Michael T. C. , Copley Phillip C. , Graves Catriona , MacKay Sinead , Duong Charis , Leung Andraay H. C. , Eames Niall , Statham Patrick F. X. , Darwish Stacey , Sell Philip J. , Thorpe Paul , Shekhar Himanshu , Roy Holly , Woodfield Julie
Published: September 2023

Aims

Patients with cauda equina syndrome (CES) require emergency imaging and surgical decompression. The severity and type of symptoms may influence the timing of imaging and surgery, and help predict the patient’s prognosis. Categories of CES attempt to group patients for management and prognostication purposes. We aimed in this study to assess the inter-rater reliability of dividing patients with CES into categories to assess whether they can be reliably applied in clinical practice and in research.

Methods

A literature review was undertaken to identify published descriptions of categories of CES. A total of 100 real anonymized clinical vignettes of patients diagnosed with CES from the Understanding Cauda Equina Syndrome (UCES) study were reviewed by consultant spinal surgeons, neurosurgical registrars, and medical students. All were provided with published category definitions and asked to decide whether each patient had ‘suspected CES’; ‘early CES’; ‘incomplete CES’; or ‘CES with urinary retention’. Inter-rater agreement was assessed for all categories, for all raters, and for each group of raters using Fleiss’s kappa.

Results

Each of the 100 participants were rated by four medical students, five neurosurgical registrars, and four consultant spinal surgeons. No groups achieved reasonable inter-rater agreement for any of the categories. CES with retention versus all other categories had the highest inter-rater agreement (kappa 0.34 (95% confidence interval 0.27 to 0.31); minimal agreement). There was no improvement in inter-rater agreement with clinical experience. Across all categories, registrars agreed with each other most often (kappa 0.41), followed by medical students (kappa 0.39). Consultant spinal surgeons had the lowest inter-rater agreement (kappa 0.17).

Conclusion

Inter-rater agreement for categorizing CES is low among clinicians who regularly manage these patients. CES categories should be used with caution in clinical practice and research studies, as groups may be heterogenous and not comparable.

Cite this article: Bone Joint J 2023;105-B(9):1007–1012.
Acetabular fractures: Epidemiology and mortality based on 2,132 fractures from the Swedish Fracture Register
Authors: Albrektsson Madelene , Möller Michael , Wolf Olof , Wennergren David , Sundfeldt Mikael
Published: September 2023

Aims

To describe the epidemiology of acetabular fractures including patient characteristics, injury mechanisms, fracture patterns, treatment, and mortality.

Methods

We retrieved information from the Swedish Fracture Register (SFR) on all patients with acetabular fractures, of the native hip joint in the adult skeleton, sustained between 2014 and 2020. Study variables included patient age, sex, injury date, injury mechanism, fracture classification, treatment, and mortality.

Results

In total, 2,132 patients with acetabular fractures from the SFR were included in the study. The majority of the patients were male (62%) and aged over 70 years old (62%). For patients aged > 70 years, the 30-day mortality was 8% and one-year mortality 24%. For patients aged ≤ 70 years, the 30-day mortality was 0.2% and one-year mortality 2%. Low-energy injuries (63%) and anterior wall fractures (20%) were most common. Treatment was most often non-surgical (75%).

Conclusion

The majority of patients who sustain an acetabular fracture are elderly (> 70 years), of male sex, and the fracture most commonly occurs after a simple, low-energy fall. Non-surgical treatment is chosen in the majority of acetabular fracture patients. The one-year mortality for elderly patients with acetabular fracture is similar to the mortality after hip fracture, and a similar multidisciplinary approach to care for these patients should be considered.

Cite this article: Bone Jt Open 2023;4(9):652–658.
Wildfire Burn Severity Affects Postfire Shifts in Evapotranspiration in Subalpine Forests
Authors: Mankin Kyle R. , Patel Rhythm
Published: September 2023

Highlights

After wildfire, actual evapotranspiration (ETa) in four subalpine areas decreased proportionally to burn severity.

High-severity burn areas maintained the highest ETa before fire and the lowest ETa after fire.

After fire, ETa decreased more in areas that had higher prefire ETa.

ETa was a useful system-level measure of susceptibility to fire and impact after fire.

Abstract. The ecohydrologic response to fire is complex, with devastating consequences for source-water hydrology. Postfire canopy structure, leaf area, infiltration, and soil-water storage all may act to reduce evapotranspiration (ET), a key hydrologic variable and indicator of ecohydrologic function. This study explored the use of 30-m resolution Landsat-based SSEBop-model estimates of actual ET (ETa) to assess the effects of fire in the Upper Rio Grande Basin (2002 Million Fire, CO; 1996 Hondo Fire, NM; 2002 Montoya Fire, NM; 2000 Cerro Grande Fire, NM). SSEBop ETa data from 1985-2019 were analyzed to better understand postfire response and recovery in several sub-alpine burned areas. Results show step reductions in ETa after fire across all burn severities in all four fire areas. Prior to the fire, ETa was generally higher in high-severity burn areas, indicative of higher fuel loads, although high variability indicated the influence of additional factors. All areas had a greater response (decreased ETa) to fire in high-severity areas and a lesser response as burn severity decreased. The decrease in ETa after high-severity fire ranged from 42% to 63%, compared to the decrease after low-severity fire, which ranged from 24% to 44%. None of the four burn areas demonstrated postfire ETa recovery after 17 to 23 years. This study demonstrates the clear utility for remote-sensing ETa estimates as a system-level measure of susceptibility to fire, impact of fire, and, potentially, recovery after fire. However, additional research is needed to account for the covariate effects of other fuel, topographic, weather, and climate factors. Keywords: Ecohydrology, Postfire recovery, Remote sensing, Upper Rio Grande Basin.
Industrial Disease and Postcolonial Affect in Michael Ondaatje's In the Skin of a Lion
Authors: Hemsley Frances
Published: September 2023

Abstract: This article examines the significance of skin for thinking about postcolonial affect by exploring "epidemiological affect" in Michael Ondaatje's In the Skin of a Lion . Epidemiological affect, the novel suggests, arises from a worker's immersion in unclean (and diseasing) industrial environments and their simultaneous position within colonial regimes of racial and hygienic cleansing. Within the novel, the skin's affective placements in exposure, ideation, and solidarity reveal a highly ambivalent process: the assimilation of racialised white immigrant identity through labour, in which assimilation means both the cleansing of difference and the acquisition of social and economic capital. Ondaatje's rendering of the affective life of the skin thus follows Achille Mbembe's recommendation: that to account for postcolonial relations of power—their effectiveness and psychology—we need to go beyond the binary categories (like passivity versus resistance) so frequently deployed in the analysis of domination. Instead, exploitable but eventually assimilable white industrial workers in the novel oscillate between resignation and jouissance—states transacted by their compromising embrace of contamination and cleansing and mediated by the text's aesthetics of submersion and explosion.
Synthesis and optical properties of Ag/Au-TiO2 plasmonic composite thin films
Authors: Yergaliyeva S. , Nemkayeva R. , Guseinov N. , Prikhodko O. , Arbuz A. , Orynbay B. , Sagidolda Ye. , Aitzhanov M. , Ismailova G. , Mukhametkarimov Y.
Published: September 2023

In this work, composite thin films based on titanium dioxide and noble metal nanoparticles (Ag, Au and bimetallic Ag/Au alloys) (Me-TiO2) were synthesized using the RF magnetron sputtering technique. The obtained thin films were characterized by TEM, SEM, XRD analysis, and Raman spectroscopy. It was observed that annealing in an argon atmosphere led to the crystallization of the initially amorphous as-deposited TiO2 matrix. The analysis of transmission spectra revealed that the composite thin films exhibited two light absorption regions: the first is local minima in the visible range associated with localized surface plasmon resonance (LSPR) phenomena; the second is light absorption due to the energy band gap. The study demonstrates the possibility of tuning these parameters in the composite films by changing the composition of the metal NPs. The LSPR minima for Ag-TiO2 and Au-TiO2 films were located at about 485 nm and 606 nm, respectively. In the composite thin films with bimetallic ∼Ag0.54/Au0.46 alloy nanoparticles, the position of the absorption peak was found to be at 555 nm. The energy band gap of these films also varies almost linearly, decreasing with an increase in the Au content, so that the largest value among the annealed Me-TiO2 composites was observed for the Ag-TiO2.
Metabolic, renal, and hematological changes in chronic hepatitis C patients achieving rapid virologic response after 12 weeks of direct-acting antiviral treatment: A prospective cohort study
Authors: Thi Thu Phuong Nguyen , Hoang Van Dung , Ngo Thi Quynh Mai , Tran Thi Ngan , Pham Minh Khue , Pham Van Linh
Published: September 2023

The impact of direct-acting antivirals (DAA) therapy on lipid and glucose metabolism and kidney function in patients with hepatitis C virus (HCV) infection, along with its side effects on blood cells, remains controversial. Therefore, we conducted a study that enrolled 280 patients with HCV infection who achieved sustained virologic response after treatment with DAA therapy without ribavirin to evaluate the metabolic changes, renal function, and anemia risk based on real-world data. This study was an observational prospective study with a follow-up period of 12 weeks after the initiation of DAA therapy. Data on biochemical tests, renal function, blood counts, viral load, and host genomics were recorded before treatment and after 12 weeks of treatment with DAAs. DAA therapy reduced fibrosis-4 scores and improved liver function, with significant reductions in aspartate transaminase, alanine aminotransferase, and total bilirubin levels. However, DAA therapy slightly increased uric acid, cholesterol, and low-density lipoprotein cholesterol levels. It significantly reduced fasting blood glucose levels and hemoglobin A1C index (HbA1C) in the study group, while hemoglobin (Hb) and hematocrit (HCT) concentrations decreased significantly (4.78 ± 21.79 g/L and 0.09% ± 0.11%, respectively). The estimated glomerular filtration rate (eGFR) decreased by 12.89 ± 39.04 mL/min/1.73m2. Most variations were not related to the genotype, except for Hb, HCT, and HbA1C. Anemia incidence increased from 23.58% before treatment to 30.72% after treatment. Patients with HCV-1 genotype had a higher rate of anemia than did patients with genotype 6 (36.23% vs. 24.62%). Multivariate analysis showed that the risk of anemia was related to female sex, cirrhosis status, fibrosis-4 score, pretreatment eGFR, and pretreatment Hb level. The results of our study can provide helpful information to clinicians for the prognosis and treatment of HCV infection.
The eHealth usage during COVID-19 pandemic 2020 year–Case of Poland
Authors: Jankowiak Maciej , Rój Justyna
Published: September 2023

According to the DESI 2022 digital economy and society ranking, Poland still ranks in one of the last position. Although, in digitising healthcare Poland has made significant progress over the last five years, some inequities in the usage of eHealth have been recognised. This has become an especially important topic after the COVID-19 pandemic. Suddenly, eHealth innovations were much needed to maintain the accessibility of healthcare. Thus, the aim of this study was to explore determinants of eHealth usage by Poles and identify existing potential barriers. Data was collected from the databases of Statistic Poland and statistical methods were employed in this research. The results showed that five variables such as Internet access, Internet use, Internet skills and average monthly disposable income per capita in PLN, along with the number of practicing physicians per capita were important determinants explaining eHealth usage by the analysed Poles between the age of 16–74. The findings showed to increase the usage of eHealth, health policy makers should ensure that Poles acquire and improve Internet skills. Based on results of the research an extended model of eHealth development in Poland, consisting of a central governmental institution and local facilities coordinating remote electronic services, collecting statistical data and providing educational campaigns, was proposed as well.
Effectiveness of artificial urinary sphincter to treat stress incontinence after prostatectomy: A meta-analysis and systematic review
Authors: Li Yue , Li Xiao , Yang Qin
Published: September 2023

Background

Artificial Urinary Sphincter (AUS) has always been considered the gold standard for surgical treatment of male non-neurogenic Stress Urinary Incontinence (SUI). The purpose of this meta-analysis was to evaluate AUS’s effectiveness in treating male SUI, as described in the literature.

Methods

Two independent reviewers used PubMed, EMBASE, Web of Science, CNKI, WanFang Data, and VIP databases, to find the efficacy of artificial urethral sphincter in treating SUI after male prostate surgery. We excluded studies on female urinary incontinence. The main purpose of this study was to evaluate the clinical efficacy based on the degree of dry rate after AUS AMS 800™: postoperative complete dry was defined as no pad use per day. Postoperative social dry was defined as 0–1 pad per day. The secondary goal was to analyze the use of AUS AMS 800™ to improve SUI and to calculate the degree of influence by analyzing the number of pads and postoperative quality of life. And methodologic quality of the overall body of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) guidelines.

Results

The data in this paper are mostly based on prospective or retrospective cohort studies without control groups. Fortunately, most studies have the same criteria to assess effectiveness. The pooled data of 1271 patients from 19 studies (6 prospective cohort studies, 12 retrospective cohort studies, and 1 randomized controlled trial) showed that: the number of pads used (pads/ day) after AUS was significantly reduced by about 4 (P < 0.001) and the quality of life was improved (P < 0.001).In addition, data analysis showed a high degree of heterogeneity between studies. According to the severity of baseline SUI, subgroup analysis was performed on the postoperative dry rate and social dry rate. Although heterogeneity was reduced, I2 is still above 50%, considering that heterogeneity may not be related to the severity of SUI. The random effect model was used for data analysis: the dry rate was about 52% (P < 0.001), and the social dry rate was about 82% (P < 0.001). The evidence level of GRADE of dry rate is very low, the evidence level of social dry rate and Pads use (pads/day) is Moderate, and the evidence level of Quality of life is low.

Conclusion

Although the evidence in this paper is based on descriptive studies and limited follow-up, the results show that AUS is effective in treating urinary incontinence and can improve patients’ quality of life.
A robot intervention for adults with ADHD and insomnia–A mixed-method proof-of-concept study
Authors: Støre Siri Jakobsson , Tillfors Maria , Angelhoff Charlotte , Norell-Clarke Annika
Published: September 2023

Objective

To investigate individual effects of a three-week sleep robot intervention in adults with ADHD and insomnia, and to explore participants’ experiences with the intervention.

Methods

A proof-of-concept study with a mixed-methods design (n = 6, female = 4) where a repeated ABA single-case study was combined with interviews. Data were collected with the Consensus Sleep Diary, wrist actigraphy, questionnaires on symptoms of insomnia, arousal, emotional distress, and ADHD, and through individual interviews.

Results

Visual analysis of the sleep diary and actigraphy variables did not support any effects from the robot intervention. Half of participants reported clinically relevant reductions on the Insomnia Severity Index from pre- to post-intervention. No changes regarding ADHD or arousal. Thematic analysis of the interviews resulted in three themes: (1) A pleasant companion, (2) Too much/not enough, and (3) A new routine.

Conclusion

Adjustments of the intervention ought to be made to match the needs of patients with both ADHD and insomnia before the next trial is conducted.
Severe mental illness and the risk of breast cancer: A two-sample, two-step multivariable Mendelian randomization study
Authors: Cui Yongjia , Lu Wenping , Shao Tianrui , Zhuo Zhili , Wang Ya’nan , Zhang Weixuan
Published: September 2023

Background

Based on epidemiological reports, severe mental illness (SMI) and breast cancer (BC) risk are linked positively. However, it is susceptible to clinical confounding factors, such as smoking, alcohol consumption, etc. Here, we performed a two-sample, two-step multivariable Mendelian randomization (MR) research to explore how the SMI etiologically influences BC risk and to quantify mediating effects of known modifiable risk factors.

Methods

Data concerning the single nucleotide polymorphism (SNP)-associated with schizophrenia, bipolar disorder (BD), major depressive disorder (MDD), and BC were obtained from two large consortia: the Breast Cancer Association Consortium (BCAC) and the Psychiatric Genomics Consortium (PGC). Then, the correlations of the previous SMI with the BC prevalence and the potential impact of mediators were explored through the two-sample and two-step MR analyses.

Results

In two-sample MR, schizophrenia increased BC incidence (odds ratio (OR) 1.06, 95% confidence interval (CI) 1.02–1.10, P = 0.001). In subgroup analysis, schizophrenia increased ER+ BC (OR 1.06, 95% CI 1.03–1.10, P = 0.0009) and ER-BC (OR 1.06, 95% CI 1.01–1.11, P = 0.0123) incidences. Neither MDD nor BD elevated the BC risk. In two-step MR, smoking explained 11.29% of the schizophrenia-all BC risk association.

Conclusions

Our study indicates that schizophrenia increases susceptibility to breast cancer, with smoking playing a certain mediating role. Therefore, BC screening and smoking should be incorporated into the health management of individuals with schizophrenia.
Against authority: Performance art in 1980s China
Authors: Qi Jianan
Published: September 2023

This article investigates the origins of performance art in China. Early forms of performance art showed a rebellious attitude against authority in the context of social and cultural change in the 1980s. This article examines the social and art historical contexts of xingwei yishu in China and its development as an art form. Through analysing early performance practices, particularly the art group Concept 21, it discusses how performance art was used as a practical approach to reform artistic creation and reception and subvert dominant cultural norms. Given China’s hierarchical art system, this article also addresses the factors that created spaces for radical performances under the art bureaucracy, including administrative reform, ambiguous guidelines, art education reform and exhibition policy.
The wedding complex: Chinese queer performance art as social activism
Authors: Bao Hongwei
Published: September 2023

Through public, intentional and interventionist displays of the queer body, queer Chinese artists have used performance art for identity expression, community building and social activism. This article focuses on some of these queer performance artworks, those that engage with the theme of weddings; that is, performance artworks that draw on and critique the social conventions of wedding ceremonies. Focusing on five case studies – the lesbian artist duo Shi Tou and Ming Ming’s photography and installation about queer women’s intimacy; queer filmmakers Fan Popo and David Zheng’s 2009 film New Beijing, New Marriage, a documentary based on a same-sex wedding performance in central Beijing; queer feminist filmmaker He Xiaopei’s performance artwork and films; the Young Feminist Activist Group’s 2012 public performance Bloody Brides to protest domestic violence against women, and the queer artist duo Cheng Yumo and Huang Ziwei’s Grand Gay Wedding performance in Zurich in 2022 – this article demonstrates that the wedding format has been used by Chinese queer artists, performers and activists in creative, innovative and critical ways; it gives new meanings to traditional wedding practices and helps rethink how queerness can relate to established social institutions and conventions in a global context. This article extends existing scholarship on performance art in the 1980s and 1990s which was predominantly male-dominated, heteronormative and elitist avant-garde art practice; it also highlights the role of performance art in contemporary China’s feminist and LGBTQ+ social movements and in articulating gender and sexual politics.
(In)visible bodies: Air pollution, performance art and China’s environmental governance
Authors: Zhang Xinrui
Published: September 2023

This article examines the presentation of visible and invisible bodies in performance art, exemplified by Praying for Blue Skies and Winter Solstice, which were responses to Beijing’s air pollution in the 2010s when the city was frequently enshrouded in severe smog. The former was staged in Beijing’s Temple of Heaven in 2014 by a group of 23 anonymous artists and the latter was created by Liu Bolin in December 2015 when seven camouflaged models danced in a withered grove on the eastern outskirts of Beijing. These two works took place during the period when Chai Jing’s Under the Dome, a 2015 multimedia documentary that investigated the causes of China’s air pollution, was censored; the (in)visibility of the bodies in both performances enabled the artists to voice their critical opinions. This article argues that visible and invisible bodies became a means of engaging in protest against the ineffectiveness of authoritarian environmentalism and performative governance in tackling air pollution. I start by explaining the concepts of authoritarian environmentalism and performative governance in China. I then discuss visible bodies, as presented in Praying for Blue Skies, in relation to Stephen Duncombe’s notion of activist art’s affect and effect. In contrast, invisible bodies, as performed in Winter Solstice, are examined within the context of Judith Butler’s theory of performativity. Finally, I explore Anthony Orum and Zachary Neal’s investigations into public spaces as sites of resistance for exposing the gaps between the government’s air pollution prevention plan and the reality of the lack of law enforcement.
A well-oiled engine: Towards a critical petro-aesthetics of Singapore
Authors: Tay Kenneth
Published: September 2023

While Singapore is not an oil-producing nation, it occupies an important role as one of the largest refinery hubs and the world’s busiest bunkering port for tankers and container ships. However, existing scholarship on petroculture has largely bypassed Singapore in its focus on direct representations of oil centred on upstream producers such as the United States, Canada and countries in the Middle East. This article traces the emergence and eventual disappearance of oil in Singapore’s visual culture through two moving images made separately in the late 1950s and the early 2000s. Comparing L. Krishnan’s film Orang Minyak (), which headlined a series of local films that featured the urban legend of the orang minyak (‘oily man’), with Tan Pin Pin’s documentary video 80km/h () allows us to consider the sudden eruption and eventual disappearance of oil in Singapore’s visual culture, set against the historical developments of Singapore’s oil industry. Of interest here is an attention towards both direct and indirect representations of oil. The article ends with a formal analysis of Tan’s 80km/h, through which I argue for a critical petro-aesthetics particular to Singapore itself, in thinking through its role as an important middleman in the global supply chain of petroleum and petrochemicals.
Sharks, spiders, snakes, oh my: A review of creature feature films
Authors: Le Busque Brianna , Litchfield Carla
Published: September 2023

Media are conduits for people to obtain information about animal species and may therefore influence how people think about these species. This study advances our understanding of animals (and plants) in the media by analysing a final dataset of 638 films categorized in the genre ‘Creature Features’. Through analysing the biography, film poster and trailer on the IMDb database, it was found that sharks were the most depicted species in creature feature films, with insects and arachnids, dinosaurs and snakes also being frequently featured. There were changes in the types of animal species commonly portrayed in creature feature films across time, with dinosaurs and primates being more frequently depicted in the 1920s–30s and sharks being more frequently depicted in recent decades. This study is the first to investigate which animal/plant species are evident in creature feature films, which is a broader genre incorporating mythology, extant and general unrealistic portrayals of animals. This allows for new understandings regarding the influence the media can have on perceptions of animal and plant species.
Finding hope, resilience and imagining ways forward through climate fiction
Authors: Tegelberg Matthew
Published: September 2023

This article explores the potential for climate fiction to function as a powerful medium of climate change communication. After briefly introducing climate fiction (colloquially known as ‘cli-fi’), I draw reflexively on past teaching experiences to argue for this potential in two main ways. First, I demonstrate how fictional climate storytelling can deepen understanding and engagement with climate science by connecting this abstract knowledge to everyday lived realities. Second, I consider how climate fiction opens pedagogically rich ways of exploring complex emotional responses to living in the climate crisis. The creative works discussed in the article each serve to illuminate the power of speculative climate fiction to engage students and wider publics in processes of imagining more sustainable, resilient, climate-friendly and just ways forward.
Cold Water Oil: Offshore Petroleum Cultures, Fiona Polack and Danine Farquharson (eds) (2021)
Authors: Damluji Mona
Published: September 2023

Review of: Cold Water Oil: Offshore Petroleum Cultures, Fiona Polack and Danine Farquharson (eds) (2021)

London and New York: Routledge, 273 pp.,

ISBN 978-0-36790-392-3, p/bk, $48.95
The effect of relationship banking on SMEs’ credit access conditions: Empirical evidence from Brazil
Authors: Bannwart Elias Guilherme , Guasti Lima Fabiano , Confetti Gatsios Rafael , Medeiros Magnani Vinícius
Published: September 2023

Objectives: Small-sized financial institutions stand out in serving SMEs due to their comparative advantages in the use of relationship-based credit. This study explores the impact of the relationship between a small financial institution and SMEs on credit access conditions. Methodology: The research employs the ordinary least square multiple regression method (OLS) on a dataset comprising 194 loan agreements from a small financial institution, which were contracted by 43 SMEs. The dataset includes financial information and records regarding the relationship strength with the creditor from 2015 to 2019. Results: The parameters of the OLS models that measured the association between the cost of credit, credit line available and average maturity with the bank relationship profile showed statistically significant results. Conclusions: The findings suggest that the duration of the banking relationship and the number of services contracted do not significantly affect the cost of credit. However, a noteworthy association is observed between credit concentration within the small-sized bank and higher costs for clients. Additionally, the length of the banking relationship directly influences the credit line available to SMEs. Interestingly, the impact of guarantees offered on credit conditions does not justify long credit transactions. Furthermore, an inverse relationship emerges between the credit rating of SMEs and the credit term.
Aportes conceptuales al diagnóstico para el ordenamiento territorial periurbano desde un abordaje sistémico y transdisciplinar
Authors: Vásquez Santos Karen , Mosquera Téllez Jemay
Published: September 2023

El estudio se enmarca en una aproximación conceptual sobre la noción multidimensional del territorio, el direccionamiento hacia la integralidad del desarrollo y los procesos de ordenamiento territorial que se llevan a cabo en Europa y Latinoamérica; en la que resalta el desconocimiento sistemático del suelo periurbano, a pesar de su rol en el desarrollo territorial. Se muestran resultados de un proceso de revisión documental, de carácter holístico y transdisciplinar cuya estructura hermenéutica permitió hacer énfasis en la importancia de la fase diagnóstica para realizar estudios efectivos de planificación, y de reconocer la importancia del periurbano como espacio adaptativo, resiliente y estratégico de transición y control de la expansión urbana, lo cual puede servir de base para la formulación de una regulación normativa que permita superar las contradicciones existentes en la interfaz urbano-rural desde una visión sostenible de largo plazo.
Comparison of Centering Ability and Canal Transportation of TruNatomy Files with Different File Systems
Authors:   Department of Endodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey, Hazar Ecehan , Geduk Gediz ,   Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey, Coşkun Ezgi ,   Dental specialist, İstanbul, Turkey, Koçak Sibel ,   Department of Endodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey, Can Sağlam Baran ,   Department of Endodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey, Murat Koçak Mustafa ,   Department of Endodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey
Published: September 2023

Objective: This study aims to evaluate the centering ability and canal transportation of the ProTaper Next, One Curve, and TruNatomy instruments in curved root canals. Methods: Forty-five curved mesiobuccal canals of human mandibular molar teeth were selected, randomly divided into 3 groups, and prepared using the ProTaper Next, One Curve, and TruNatomy files. Cone Beam Computed Tomography images of the cross-sectional planes at 1 mm, 3 mm, 5 mm, and 7 mm from the apical foramen were determined before and after the preparation. For each specified millimeter canal transportation and centering ability were measured. Statistical analysis was performed and compared all groups. Results: No significant differences were observed between the groups or root canal levels in both canal transportation and centering ability (p > 0.05). Conclusion: The TruNatomy system demonstrated comparable results with both predecessor ProTaper Next and One Curve single-file systems.
The Effects of Boric Acid on The Water Solubility of Glass Ionomer Cements
Authors:   Department of Prosthodontics, Private Dental Clinic, Ankara, Turkey, Cukurluoz Bayındır Banu , Bağ İrem ,   Department of Pediatric Dentistry, Faculty of Dentistry, Eskişehir Osmangazi University, Eskişehir, Turkey
Published: September 2023

Changing the water solubility property of glass ionomer cement (GIC), which is frequently used in pediatric dentistry, is the starting point of this study. Objective: To evaluate the effects of boric acid on the water solubility (WS) of GIC. Methods: The samples were prepared as n=12 in each of four groups: GIC-Conventional glass ionomer cement; BGIC with 1:3 boric acid added to conventional GIC powder; RMGIC-resin-modified glass ionomer cement; BRMGIC with 1:3 boric acid added to RMGIC powder. Weight changes were compared 1, 3 and 24 h after keeping in distilled water. One sample in each group was measured by SEM-EDX analysis. The data were analyzed using a one-way analysis of variance, Dunnett’s T3 in multiple comparison tests, and generalized linear models. Results: In all groups, water solubility increased. There was a significant difference between the mean values of the WS-1h, WS-3h, and WS-24h variables in each group and between the GIC, BGIC, RMGIC, and BRMGIC groups in the mean values of the WS-1h, WS-3h, and WS-24h variables. The SEM-EDX analysis revealed 14.19–18.47%; 0.80–1.00%; 8.69–14.91%; 0.09–13.10% boron minerals in GIC, BGIC, RMGIC, and BRMGIC, respectively. Conclusion: The addition of boric acid led to an increase in water solubility. The effects of boric acid on the GIC samples emphasized its potential role in altering the cement’s physicochemical properties. Therefore, it is important to consider carefully when using boric acid as a supplement in GIC formulations for dental applications.
Morbus Hansen
Authors: Idris Fitria , Mellaratna Wizar Putri
Published: September 2023

Morbus Hansen (MH) which is called leprosy or leprosy is an infectious disease that causes health problems throughout the world. Leprosy is spread all over the world, especially in tropical and subtropical areas and attacks all ages with the highest frequency in the age group of 20 to 30 years. Case Presentation : Mr. AB, male, aged 33 years, came complaining of numbness and frequent tingling. Hands and feet began to swell and sore. Some toenails fall off unnoticed. Physical examination found composmentis awareness. The general status of the patient was madarosis in both eyelashes, the eyes looked anemic. Ears found infiltrates in both earlobes. Dermatological status in the facial region and superior extremities showed multiple hyperpigmented macules and patches, well defined, geographic shape, sizes vary. Bacteriological examination with Slit Skin Smear on the earlobes found 1-10 Acid-Fast Bacilli (AFB) / 100 fields of view (+1). Bacteriological Index obtained +1. Conclusion: The patient was diagnosed with MB type leprosy accompanied by Erythema Nodusum Leprosum
THE EFFECT OF TABURIA FORTIFICATION AND NUTRITION EDUCATION OF MOTHERS TO ON NUTRITIONAL STATUS OF 12-24 MONTHS OLD CHILDREN IN INDONESIA : RANDOMIZED CONTROLLED TRIAL STUDY
Authors: Wahyuni Yulia , Mexitalia Maria , Rahfiludin M. Zen
Published: September 2023

ABSTRACTBackground: Mother's nutritional knowledge and parents' feeding practices will influence children's eating behavior which have an impact on the child's growth.Objective: The purpose of this study was to determine the effects of Taburia fortification and nutrition education of mothers on the nutritional status of children in Waipare Public health center in East Nusa Tenggara.Materials and Methods: This study was a randomized controlled trial. A total of 180 mothers and their children aged 12-24 months who had malnourished (z-score -3 to -2). The group divided into teams were the intervention group (IG) (n=90) and the control group (CG) (n=90). The IG give intervention for three months. The mothers were given nutrition education, while their children were given taburia. The CG, mothers were given nutrition education. Data feeding rules obtained using a self-administered feeding practice-Questionnaire (FPQ). Dietary intake assessment of macronutrient and micronutrient three-day food records, nutritional status, and percentage of child's sick day was conducted before and after the intervention.Results: The result of the study showed that there was no significant difference in the mean increase (P> 0.01) between knowledge scores in IG and CG, post-intervention. Lower percentage of sickness among children in IG than CG. The average nutrient intake, WAZ (0.97±0.52), WLZ (1.02±0.42) of IG increased and was higher than CG after the intervention. The LAZ of IG increased (0.34±0.66 SD) while on the CG declined (0.27±0,31 SD).Conclusion: Thus, The Taburia fortification intervention was useful in improving WAZ, LAZ, WLZ in children who experienced malnutrition, but the intervention nutrition education of mothers can increase WAZ and WLZ.
HUBUNGAN PENGETAHUAN DAN SIKAP HYGIENE SANITASI DENGAN PERILAKU PERSONAL HYGIENE PADA PENJAMAH MAKANAN KAKI LIMA DI KECAMATAN TAPOS KOTA DEPOK
Authors: Putri Rara Maulidya , Fayasari Adhila
Published: September 2023

ABSTRAKLatar belakang: Personal hygiene merupakan suatu tindakan pencegahan penyakit terhadap seseorang dengan lingkungan tempat tinggal. Penjamah makanan kaki lima merupakan suatu upaya individual yang berjualan makanan ditempat keramaian seperti ditepi jalan, di rumah sakit, disekolah dan lain sebagainya. Masalah kesehatan yang erat bagi tubuh yaitu masalah kebersihan dan sanitasi pada makanan. Hal tersebut dikarenakan pengetahuan, sikap dan perilaku sangat berperan dalam sanitasi pada makanan sehingga dapat menghindari pencemaran yang terjadi pada makanan.Tujuan: Untuk menganalisis hubungan pengetahuan dan sikap hygiene sanitasi terhadap perilaku personal hygiene pada penjamah makanan kaki lima di Wilayah Kecamatan Tapos Kota Depok. Metode: Penelitian ini menggunakan desain cross sectional pada penjamah makanan kaki lima di wilayah Kecamatan Tapos pada bulan Mei-Juni 2022. Kriteria inklusi, Subjek berumur 20-60 tahun, bersedia menjadi subjek dalam kondisi sehat, subjek merupakan penjamah makanan kaki lima makanan tradisional. Penelitian ini menggunakan pertanyaan pengetahuan dan sikap hygiene sanitasi, serta pengamatan pada perilaku personal hygiene. Analisis data menggunakan analisa univariat dan bivariate dengan uji chi square dan p-value <0,05 dengan bantuan program aplikasi statistic dalam pengolahannya.Hasil: Hasil analisis statistik menyatakan ada hubungan antara pengetahuan hygiene sanitasi terhadap perilaku personal hygiene (p<0,001), ada hubungan antara sikap hygiene sanitasi terhadap perilaku personal hygiene (p=0,048).Simpulan: Ada hubungan antara pengetahuan higiene sanitasi terhadap perilaku personal hygiene dan ada hubungan antara sikap hygiene sanitasi terhadap perilaku personal hygiene.Kata kunci: Hygiene Sanitasi; Pengetahuan; Perilaku; Personal Hygiene; Sikap
HUBUNGAN KONSUMSI SUPLEMEN PROTEIN DENGAN MASSA OTOT PADA ANGGOTA LEMBAH FITNESS CENTRE TAJEM, YOGYAKARTA
Authors: Wihelmina Maria , Afriani Yuni , Yuliati Endri
Published: September 2023

ABSTRAKLatar belakang: Suplemen merupakan produk kesehatan yang mengandung satu atau lebih zat yang bersifat nutrisi atau obat. Pembentukan massa otot yang optimal membutuhkan zat gizi, salah satunya adalah protein.Mempunyai massa otot yang baik menjadi salah satu tujuan seseorang mengikuti latihan pada fitness centre.Tujuan: Penelitian ini bertujuan unntuk mengetahui hubungan konsumsi suplemen protein dengan massa otot pada anggota  fitness centre di Lembah Fitness Centre Tajem.Metode: Jenis penelitian yang digunakan adalah observasional, dengan desain cross sectional. Jumlah responden dalam penelitian ini adalah 40 orang anggota fitness centre yang aktif dan berusia 20 – 35 tahun. Data konsumsi suplemen diperoleh dengan wawancara langsung menggunakan kuesioner konsumsi suplemen sedangkan massa otot diperoleh dari pengukuran LOLA (lingkar otot lengan atas) dan LILA (lingkar lengan atas) dengan 3 kali pengulangan. Analisa data menggunakan uji chi-square.Hasil: Hasil penelitian menunjukkan sebagian besar responden tidak mengkonsumsi suplemen yaitu sebanyak 25 orang (62,5%) dan memiliki massa otot dalam kategori normal yaitu 33 orang (82,5%). Hasil analisis statistik menunjukkan tidak ada hubungan antara konsumsi suplemen dan massa otot (p > 0,05).Simpulan: Konsumsi suplemen protein tidak berhubungan dengan massa otot. Diperlukan penelitian lebih lanjut dengan mengendalikan variabel-variabel perancu seperti asupan protein dari makanan dan intensitas latihan.
Pengaruh Industri Mikro dan Kecil terhadap Kemiskinan di Wilayah Daerah Istimewa Yogyakarta
Authors: Dhiyaa'ulhaq Mishbahuddin , Sahara Sahara , Juanda Bambang
Published: September 2023

Kemiskinan masih menjadi masalah utama dalam pembangunan bagi setiap daerah, termasuk Daerah Istimewa Yogyakarta. Kemiskinan sendiri terjadi salah satunya karena disebabkan oleh tingginya tingkat pengangguran, ketimpangan pembangunan antara daerah perdesaan dan perkotaan ikut menjadi penyebab semakin tingginya tingkat kemiskinan di daerah perdesaan.  Industri mikro dan kecil merupakan sektor yang dapat tumbuh di seluruh wilayah dan menyerap tenaga kerja dalam jumlah banyak. Tujuan dari penelitian ini adalah menganalisis pola penyebaran kemiskinan dan pengaruh indsutri mikro dan kecil terhadap kemiskinan di wilayah D.I. Yogyakarta. Metode analisis yang digunakan adalah analisis Moran’s I, Moran’s Scatterplot, Local Indicator of Spatial Autocorrelation (LISA), dan analisis model regresi Geographically Weighted Regression (GWR). Hasil analisis memperlihatakan adanya pola hubungan spasial persentase penduduk miskin antar kecamatan, dengan tiga pola hubungan, yaitu High-High (HH), Low-Low (LL), dan  Low-High (LH). Tenaga kerja dan investasi industri mikro dan kecil secara siginifikan dapat mengurangi persentase kemiskinan di sebagian besar kecamataan di D.I. Yogyakarta, kecuali di kecamatan yang berada di wilayah Kota Yogyakarta dan sekitarnya.
Persistent hypoxia promotes myofibroblast differentiation via GPR‐81 and differential regulation of LDH isoenzymes in normal and idiopathic pulmonary fibrosis fibroblasts
Authors: Nho Richard S. , Rice Cami , Prasad Jayendra , Bone Hannah , Farkas Laszlo , Rojas Mauricio , Horowitz Jeffrey C.
Published: September 2023

Hypoxia, a state of insufficient oxygen availability, promotes cellular lactate production. Lactate levels are increased in lungs from patients with idiopathic pulmonary fibrosis (IPF), a disease characterized by excessive scar formation, and lactate is implicated in the pathobiology of lung fibrosis. However, the mechanisms underlying the effects of hypoxia and lactate on fibroblast phenotype are poorly understood. We exposed normal and IPF lung fibroblasts to persistent hypoxia and found that increased lactate generation by IPF fibroblasts was driven by the FoxM1‐dependent increase of lactate dehydrogenase A (LDHA) coupled with decreased LDHB that was not observed in normal lung fibroblasts. Importantly, hypoxia reduced α‐smooth muscle actin (α‐SMA) expression in normal fibroblasts but had no significant impact on this marker of differentiation in IPF fibroblasts. Treatment of control and IPF fibroblasts with TGF‐β under hypoxic conditions did not significantly change LDHA or LDHB expression. Surprisingly, lactate directly induced the differentiation of normal, but not IPF fibroblasts under hypoxic conditions. Moreover, while expression of GPR‐81, a G‐protein‐coupled receptor that binds extracellular lactate, was increased by hypoxia in both normal and IPF fibroblasts, its inhibition or silencing only suppressed lactate‐mediated differentiation in normal fibroblasts. These studies show that hypoxia differentially affects normal and fibrotic fibroblasts, promoting increased lactate generation by IPF fibroblasts through regulation of the LDHA/LDHB ratio and promoting normal lung fibroblast responsiveness to lactate through GPR‐81. This supports a novel paradigm in which lactate may serve as a paracrine intercellular signal in oxygen‐deficient microenvironments.
Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease
Authors: Oto Ozgur A. , Atwood Daniel J. , Chaudhary Anjana , He Zhibin , Li Amy S. , Wempe Michael F. , Edelstein Charles L.
Published: September 2023

Metformin (MET) has the potential to activate p‐AMPK and block mTORC1‐induced proliferation of tubular cells in PKD kidneys. The aim of this study was to determine the effects of MET on cyst growth, kidney function, AMPK and mTOR signaling, and lactate levels in male PCK rats, a Pkhd1 gene mutation model of human autosomal recessive polycystic kidney disease (ARPKD). MET 300 mg/kg/day IP from days 28 to 84 of age resulted in a mean serum metformin level that was 10 times the upper limit of therapeutic, no effect on cyst indices, nephrotoxicity, and increased serum lactate. MET 150 mg/kg resulted in a therapeutic serum metformin level but had no effect on kidney weight, cyst indices, kidney function, or mTOR and autophagy proteins. In summary, a standard dose of MET was ineffective in reducing PKD, did not activate p‐AMPK or suppress mTOR and the higher dose resulted in increased lactate levels and nephrotoxicity. In conclusion, the study dampens enthusiasm for human studies of MET in PKD. Doubling the metformin dose resulted in a 10‐fold increase in mean blood levels and toxicity suggesting that the dosage range between therapeutic and toxic is narrow.
The crystal structure of poly[bis(μ
2-1,4-bi(1-imidazolyl)benzene-κ
2
N:N′)bis(μ
2-4,4′-methylenebis(3-hydroxy-2-naphthoate)-κ
2
O:O′)cobalt(II)], C35H24CoN4O6
Authors: Qi Ji , Wang Shu-Ying , Chu Jin-Feng
Published: September 2023

C35H24CoN4O6, monoclinic, P21/n (no. 14), a = 11.444(2) Å, b = 11.648(2) Å, c = 21.478(4) Å, β = 97.05(3)°, V = 2841.5(10) Å3, Z = 4, R

gt
(F) = 0.0849, wR
ref(F
2) = 0.1393, T = 153(2) K.
Middle Bronze Age Settlement in Czeladź Wielka – The Next Step Toward Determining the Habitation Model, Chronology, and Pottery of the Silesian-Greater Poland Tumulus Culture
Authors: Romaniszyn Jan , Staniuk Robert , Silska Patrycja , Skrzyniecka Weronika , Talarczyk-Andrałojć Małgorzata
Published: September 2023

The article presents the results of research on the habitation model, chronology, and pottery production of the Silesian-Greater Poland Tumulus Culture at Czeladź Wielka settlement (Góra county). The site of the Czeladź Wielka is the first published settlement of the Tumulus culture from the area, providing the first evidence for developing a model of habitation change between the Early and Late Bronze Age. The typochronological analyses allowed positioning the finds in the Middle Bronze Age, while radiocarbon dating placed the site between the late sixteenth and fifteenth century BC. Quantification of technological traits were used to define the general characteristics of Tumulus culture pottery in the region showing the preference for coarse, undecorated, or textile-impressed ceramics. Spatial analyses indicate the presence of a clustered settlement pattern characterized by discard of ceramic material in cultural layer. The findings suggest continuity of certain cultural traits from the preceding Únětice and the influence of contemporary Trzciniec cultural circle.