bluuebunny/crossref_metadata_2025 huggingface dataset:
तन्यता दूरीकरणोपायः
Authors: - Sujan Biswas
Published: August 2024

यदि अस्माकं जीवने तन्यता भवति तर्हि वयं सम्यग्रुपेण शारीरिकरीत्या मानसिकरीत्या स्वस्थ्यं भुत्वा जीवितुं न शक्नुमः। तदर्थं तन्यता अवश्यमेव दूरीकरणीया। अतः अस्माकं तन्यता दूरीकरणोपायः ज्ञातव्यः। सुतरां तन्यता दुरीकरणोपायः अस्माकं कृते अतीव महत्वपूर्णं भवति। तदर्थं तन्यतायाः लक्षणानि ज्ञातव्यः।
यथा- मानसिकलक्षणम्, शारीरिकलक्षणम्, भावनात्मकलक्षणम्, व्यवहारात्मकलक्षणम् इत्यादयः।
तन्यतायाः कारणानि ज्ञातव्यः। यथा- 1. कस्यचित् प्रियजनस्य मृत्युः, विवाहविच्छेदः, आर्थिकसङ्कटः, बालानां शिक्षा, तेषां विवाहः, उत्तरदायी भूत्वा अपि उल्लङ्धणभावना इत्यादयः।
तन्यतायाः दुष्प्रभावाः ज्ञातव्यः। यथा- उच्चरक्तचापः, हृदयरोगः, मधुमेहः, मानसिकं असन्तुलनम् इत्यादयः।
तन्यतापनाय केचन सरलाः उपायाः ज्ञातव्यः। यथा- दिनचर्यायाः परिवर्तनम्, भोजनस्य तारतम्यः, शरीरचर्चा, जीवनस्य प्रति दृष्टिकोणः, पारिवारिकं उत्तरदायित्वस्य अनुपालनं, कार्यव्यवस्थायां समयनिर्धारणम् इत्यादयः।
A Comprehensive Analysis of Intercompany Transfer of Assets Using Blockchain
Authors: - Divya Koppolu , - Vepa Sudha
Published: August 2024

The intercompany transfer of assets involves the movement of assets between different entities within a corporate group, such as subsidiaries or divisions. This process is vital for optimizing resource allocation, financial reporting, and regulatory compliance. However, traditional methods of managing these transfers often face significant challenges, including issues with valuation accuracy, regulatory compliance, administrative inefficiencies, and security risks. This article provides a comprehensive analysis of how blockchain technology can address these challenges and transform the intercompany asset transfer process.
Blockchain technology, characterized by its decentralized ledger, immutability, and transparency, offers potential solutions to the inherent problems in traditional asset transfers. By implementing blockchain, companies can achieve more accurate asset valuations through real-time data and automated valuation models, ensure simplified compliance with transfer pricing rules and financial reporting standards through immutable and transparent records, and reduce administrative burdens by automating transactions with smart contracts. Additionally, blockchain enhances security and fraud prevention by providing a tamper-proof, decentralized record of all asset transfers.
The article includes an examination of current challenges in intercompany asset transfers, such as difficulties with accurate valuation and pricing, compliance with complex regulatory requirements, administrative inefficiencies, and vulnerabilities to fraud. It also explores how blockchain's key features—decentralization, immutability, transparency, and smart contracts—can directly address these challenges.
Practical applications are illustrated through case studies of global organizations that have implemented blockchain solutions for managing intercompany asset transfers. These case studies highlight improvements in operational efficiency, accuracy, and regulatory compliance. The article also discusses the challenges associated with integrating blockchain with existing systems, navigating regulatory and legal issues, and managing implementation costs.
Looking ahead, the article considers the future prospects of blockchain in this context, including potential technological advancements, increasing industry adoption, and evolving regulatory landscapes. It concludes that while blockchain technology offers substantial benefits for intercompany asset transfers, successful implementation requires careful planning, integration, and ongoing adaptation to regulatory changes.
This comprehensive analysis underscores the transformative potential of blockchain for improving the efficiency, accuracy, and security of intercompany asset transfers, providing valuable insights for practitioners and researchers interested in modernizing asset management processes within corporate groups.
A Case Report on Bupropion Induced Febrile Delirium & Reversible Liver Injury
Authors: - Jomol Mathew , - Jeeva Elizabeth Thomas , - S.K Mathew
Published: August 2024

Bupropion, an atypical antidepressant and smoking cessation aid, is generally well-tolerated but has been linked to rare instances of hepatotoxicity. We report a case of a 81-year-old non alcoholic male who developed jaundice, fatigue, and right upper quadrant discomfort three months after starting bupropion. Laboratory tests showed elevated liver enzymes and hyperbilirubinemia, while extensive workup excluded other causes of liver dysfunction. The temporal association with bupropion and exclusion of other etiologies led to a diagnosis of bupropion-induced liver injury. Discontinuation of bupropion and supportive care resulted in gradual improvement and normalization of liver enzymes and resolution of fever and delirium state within three months. This case underscores the importance of considering bupropion-induced febrile delirium and reversible liver injury in patients with unexplained liver dysfunction and highlights the necessity for early recognition and drug cessation for recovery. Bupropion is also known to cause unexplained delirium. Conditions which can result in such a state can range from very diverse perspectives, such as infectious conditions like pneumonia or urinary tract infections, metabolic disorders like electrolyte imbalance, and disorders of the central nervous system like encephalitis. Keen medical evaluation is very essential for determining the root cause, as treatment mostly depends on prompt action for causative diseases to avoid further complications.
Tribal’s Dance, Songs and Music of Soligas in Karnataka
Authors: - Chethan Kumar C
Published: August 2024

Tribal is one of the interesting community in India and they have variety of culture and norms in their community. Dance and music is one of the core parts of their culture. Dances and music they celebration are performed for every possible occasion: to celebrate the arrival of seasons, the birth of a child, a wedding and festivals, social activities such as hunting and food gathering. Karnataka has one of the states having more population of tribal people in India. Toda, Beda, Soliga, Hakki-Pikki, Konda Kaapu, Koraga, Bhils, Chenchu, gonds, etc. In Southern Karnataka Soligas are mainly distributed in the interior of the forests skirting the slopes of the Biligirirangan (BR Hill) hills and other hilly part of Chamrajanagar and Mysore districts. The Rotti Habba(Food Festval) was held in March-April every year, this is the famous festival for soliga people and during that time; they are arrange many religious program with dance they called “Kunitha”(Dance). Especially in this evening they arrange famous dance called “Goru Goruka Gorukana” dance with “Tamatte”(Drum) music was performed. Especial in this song males only dance with group song with tamatte in circle form. All females and other people observe carefully and enjoying dance, during this song and dance time, this community provide very big freedom for unmarried female, and this song and dance have a big meaning. This paper is analyzed and introduce the important culture of Soliga Tribes like dance, music and songs of Chamarjangar district of southern Karnataka, India.
Beyond the Breath: Unveiling the Mysteries of Death
Authors: - Arundhati Pandit
Published: August 2024

The investigation of death is an indispensable aspect of forensic science, with the primary objective of unravelling the circumstances surrounding deaths that are either unexplained or deemed suspicious. This intricate field encompasses a variety of disciplines, including but not limited to pathology, toxicology, and criminalistics, collectively working together to piece together the puzzle of each case. In the upcoming paper, a comprehensive exploration will be conducted into the various aims, methodologies, recent breakthroughs, and real-life examples that shed light on the process of investigating death within the realm of forensic science. The central focus of this paper will revolve around underlining the key goals, detailed investigative approaches, cutting-edge advancements, and impactful case studies that delineate the sheer importance and evolutionary trajectory of death investigations, thus underscoring its crucial role in the field of forensic science.
Teacher’s Readiness for Competence-based Curriculum on Students’ Academic Performance in Secondary Schools, Wakiso District Uganda
Authors: - Nankubuge Mariam , - Nabukeera Madina , - Matovu Musa , - Ssali Muhammadi Bisaso
Published: August 2024

Teacher’s readiness is critical in the event of enrolling particular curricular given the fact that teachers form an integral part necessary for its success. This study intended to examine the influence of teacher’s readiness for the Competence-Based Curriculum on Students Academic Performance in selected secondary schools in Wakiso district. An exploratory research design that was quantitative and quantitative in approach was adopted. Data was collected using a Questionnaire survey method involving use of structured questionnaires distributed in two secondary schools (private and government aided). The target population of the study was 146, with a sample size of 30 respondents whose sampling technique was both simple random and purposive to include O-level teachers, head teachers, deputy headteachers and Directors of Studies. Specifically, the study objectives were to; a) To explore the effect of teacher’s practices on implementation of competence-based curriculum on students’ academic performance. b) Assess the impact of teachers’ professional development in competence-based curriculum on academic performance of students c) Assess the effect of teachers’ adaptability to the competence-based curriculum on the academic performance of students and d) Analyzing the impact of the challenges teachers face in implementing the Competence-Based Curriculum on academic performance of students in Wakiso district. The findings indicated that teachers’ practices in implementing the CBC have a strong positive and significant effect on the academic performance of students in Wakiso district. It was also revealed that professional teacher development in the CBC has a moderate positively significant effect on the performance of students. Additionally, the study indicated that teacher adaptability to the competence-based curriculum has a strong positive and significant effect on the academic performance of students in secondary schools of Wakiso district. Further; it was also unveiled that the challenges of teachers in implementing the competence-based curriculum have a weak negative and significant impact on students’ academic performance in selected secondary schools in Wakiso district. Therefore, the study concludes that teacher’s readiness for the CBC in terms of its implementation, professional teacher development in the CBC, teachers’ adaptability to the CBC, and teachers’ challenges in implementing the CBC has a significant influence on the academic performance of students in the selected secondary schools in Wakiso District.
Intralesional Betamethasone in Management of a Large Recurrent Labial Mucocele - A Case Report and Review of Literature
Authors: - Siddharth Singh , - Chayan Kumar Kundu , - Sudip Chakraborty , - Richi Burman
Published: August 2024

Context : Oral mucocele is one of the most common lesion affecting the minor salivary glands and is commonly known to affect the lower labial mucosa with trauma from lip biting being one of the frequent causative factors. The diagnosis of a mucocele is in its clinical presentation of a clear fluid filled or a bluish translucent bump on the labial mucosa with history of regression and recurrence. Amongst various methods available for its management, surgery has been a mainstay of treatment but is known to be associated with lip disfigurement, damage to adjacent canaliculi and development of satellite lesions.

Aim : The aim of this study was to describe a case of recurring lower labial mucocele, treated by a non-surgical approach using intralesional betamethasone and to evaluate the outcome of this treatment so that a non-invasive management of such lesion may be used as an alternative to surgery.

Result : Complete regression of the mucocele was seen with application of intralesional Betamethasone.

Conclusion : Intralesional Betamethasone may be opted as an alternative to surgery in management of labial mucocele.
Remote sensing and GIS applications for Geomorphological characteristics in parts of Singrauli district, Madhya Pradesh, India
Authors: - Koppu Thirupathi , - Ram Raj Mathur
Published: August 2024

Geomorphology is a scientific discipline that focuses on the study of the form and structure of the earth's surface. Geomorphological characteristics play a crucial role in understanding topography, landforms, and hydrological parameters. Remote sensing and GIS are widely used and popular to analyse morphological parameters. The spatial distribution of topographic attributes can often be used as an indirect measure of the spatial variability of these processes and they can be mapped using relatively simple techniques like digital elevation models. The Cartons-1 satellite image and data from various sources were used for the creation of such models. The digital elevation model has been applied to the area lying between latitude 240 24' and 240 28' and longitude 820 15' and 820 21' in the Singrauli district of Madhya Pradesh to decipher the geomorphological characteristics. Using the models created from remote sensing and GIS from the maps of NRSC the spatial distribution of the geomorphological characteristics in the Singrauli district of Madhya Pradesh have been clearly demarcated.
Social Democracy As Conceived by Dr. B.R. Ambedkar under Indian Constitution
Authors: - Dr Nitin Govindrao Wathore
Published: August 2024

Abstract:
Dr. Ambedkar will be remembered for all time to come as the architect of the Indian Constitution, specially for the Fundamental Rights and Directive Principles Chapters which, aim at eradicating "all injustice and tyranny" and ushering in social democracy and social equality. He was however, disappointed that the dominating section of our society did not rise to the occasion and did not water the plants that he had planted. It is now for human rights groups and grassroots activists to make social democracy and equality a way of life in the absence of which political democracy will always stand on a shaky foundation. Caste system and discrimination are major stumbling block to national integration, economic development, and moral regeneration of Indian society. Hence for the successful functioning of democracy in India and for the people to appreciate the fruits of equality as provided through the various articles of the Constitution, the disruptive institutions should be kept away. It will be difficult to wipe out an age old tradition with one stroke of the pen and it would continue to prick the society for many more decades to come, but the attitude of the people should change and with all sincerity, the people and also those at the controls of affairs should try to implement the provisions of the Constitution.
Predicting Agriculture Sustainability in Subak Pulagan as World Cultural Landscape of Bali: Bayesian Networks Approach
Authors: Suasih Ni Nyoman Reni , Mustika Made Dwi Setyadhi , Pratiwi Anak Agung Manik , Mahaendrayasa Made Sinthya Aryasthini , Saraswati I Gusti Ayu Prili , Krisnayanti Ni Made Nami
Published: August 2024

Subak is a farmers' organization as an institution managing rice farming irrigation in Bali which has been around for thousands of years. Subak reflects the philosophical concept of Tri Hita Karana which unites the spirit world, the human world and nature. Subak Pulagan is one of five sites in Bali designated by United Nations Educational, Scientific and Cultural Organization (UNESCO) as a world cultural landscape. The aim of this research is to identify key factors for agricultural sustainability in Subak Pulagan in terms of various institutional (people), profit and environmental (planet) components. The analysis technique uses a Bayesian network, where data was previously collected through Focus Group Discussion (FGD). The results of the analysis show that the opportunity for agricultural sustainability in Subak Pulagan is quite high. If we look at the three pillars of sustainability, if ‘profit’ is in maximum condition, it can provide the greatest opportunity to realize sustainable agriculture. If viewed from institutions (the role of government and the role of Subak), the possibility of sustainable agriculture will increase if these two institutions are also optimized. So farmer welfare (profit component) must be pursued, including through agricultural institutions. Incentive assistance through the transmission of land and building taxes, fertilizer, access to capital, and agricultural insurance are forms of incentives that the government can pursue.
Participação social no monitoramento da biodiversidade em Carajás: perfil socioeconômico, análise de percepção e relatos de experiências
Authors: Rêgo Mendes Keila , da Costa Dias Romel , Lima Figueiredo Amanda , Silva Costa Wendelo , Façanha Guedes Raimundo , Caldeira Gomes Gabriel , Macêdo Vieira André
Published: August 2024

Os programas de monitoramento da biodiversidade são fundamentais para acompanhar o estado dos ecossistemas, espécies alvo ou processos naturais e fornecer informações provenientes das análises de resposta dos alvos Ã s mudanças ambientais e ações de manejo. Nesse contexto, insere-se o Programa Nacional de Monitoramento da Biodiversidade do ICMBio - Programa Monitora, sendo um programa governamental, contínuo e de longa duração, voltado para o monitoramento do estado de conservação da biodiversidade, realizado em unidades de conservação federais geridas pelo ICMBio. A participação de diferentes atores caracteriza a base do Programa Monitora como monitoramento participativo. Assim, o presente estudo visa apresentar o perfil socioeconômico dos monitores, a análise de suas percepções e os relatos de suas experiências no Programa Monitora nas áreas protegidas presentes no Núcleo de Gestão Integrada de Carajás - NGI Carajás. Para isso, foi utilizado um questionário eletrônico aplicado através da ferramenta Microsoft Forms. Os dados foram resumidos usando estatísticas descritivas convencionais. As variáveis categóricas foram descritas em números absolutos e percentagens. No total, 46 monitores responderam ao questionário eletrônico. Os monitores que responderam o formulário eletrônico são 67% do gênero feminino e 33% do gênero masculino, apresentando idade entre 20 e 39 anos, para o gênero feminino, e entre 22 e 42 para o gênero masculino. A média de filhos por monitor é inferior a um (0,3). Os monitores apresentam uma variedade de situações conjugais, sendo a maioria solteiros, representando 76% do total. Em relação Ã  escolaridade, 50% possuem nível superior completo e 17% têm pós-graduação. Assim, foi observado que o Programa Monitora nas áreas protegidas de Carajás atrai principalmente os estudantes com formação acadêmica, sendo necessário um esforço da gestão do NGI Carajás para envolver um grupo socialmente diversificado, contribuindo para o aprimoramento da participação social na gestão da sociobiodiversidade.
Social Defense Strategy in Handling Maritime Border Issues in Eastern Indonesia (Case Study on Natuna Island)
Authors: Pandoe Ridha Munawir Masly , Sumantri Siswo Hadi , Suwarno Panji , Widodo Pujo
Published: August 2024

Pulau Natuna yang terletak strategis di Selat Karimata dan Laut Cina Selatan, menghadapi tantangan signifikan dalam pengelolaan perbatasan laut dan pertahanan sosial. Ketegangan geopolitik di kawasan ini, yang melibatkan klaim teritorial yang tumpang tindih dan aktivitas ilegal di laut, menuntut strategi pertahanan yang komprehensif dan terintegrasi. Penelitian ini bertujuan untuk menganalisis strategi pertahanan sosial yang diterapkan di Pulau Natuna dengan menilai peran pemerintah pusat dan daerah, pengawasan dan penegakan hukum, serta pemberdayaan masyarakat lokal. Metode penelitian yang digunakan adalah studi kepustakaan yang melibatkan analisis mendalam terhadap berbagai sumber hukum, literatur akademik, dan laporan pemerintah. Hasil penelitian menunjukkan bahwa kolaborasi antara pemerintah pusat dan daerah, penggunaan teknologi canggih dalam pengawasan, serta pemberdayaan masyarakat lokal adalah kunci dalam menghadapi tantangan perbatasan laut. Penelitian ini menegaskan pentingnya integrasi dan koordinasi antara berbagai pihak untuk menjaga kedaulatan dan keamanan wilayah Pulau Natuna secara efektif.
How spammers and scammers leverage AI-generated images on Facebook for audience growth
Authors: DiResta Renée , Goldstein Josh A.
Published: August 2024

Much of the research and discourse on risks from artificial intelligence (AI) image generators, such as DALL-E and Midjourney, has centered around whether they could be used to inject false information into political discourse. We show that spammers and scammers—seemingly motivated by profit or clout, not ideology—are already using AI-generated images to gain significant traction on Facebook. At times, the Facebook Feed is recommending unlabeled AI-generated images to users who neither follow the Pages posting the images nor realize that the images are AI-generated, highlighting the need for improved transparency and provenance standards as AI models proliferate.
Penerapan Metode Profile Matching untuk Menentukan Program Pemberdayaan Masyarakat pada Desa S1 Jati Baru
Authors: Perwira Yuda , Apriani Wira , Nuraisana Nuraisana , Affandi Egi , Daulay Suandi
Published: August 2024

This research aims to test the effectiveness of applying the Profile Matching method in determining community empowerment programs in Desa S1 Jati Baru. Desa S1 Jati Baru, a village in the Pagar Merbau sub-district of Deli Serdang Regency, North Sumatra Province, faces several development challenges. In this context, this research considers the Profile Matching method as a potential approach to formulate more relevant and sustainable empowerment programs. The study employs a qualitative approach involving in-depth interviews and focus group discussions with various stakeholders in Desa S1 Jati Baru. The collected data is then analyzed using content analysis methods to identify the community's needs, aspirations, and potential. The research findings indicate that the Profile Matching method provides a deeper understanding of the needs and aspirations of the Desa S1 Jati Baru community. Based on the generated profile, various empowerment programs that better match the community's characteristics and needs were identified, with the development of agricultural MSMEs emerging as the best option with the highest total score of 2.36. This program received high scores on core factors, indicating that it is highly suitable for the community's educational background, with most residents being vocational high school graduates, and has great potential to increase the village's income.
Exploring EFL Students’ Perspectives: Integrating Mind Mapping as a Cognitive Tool in Academic Writing Class
Authors: Tupalessy Pricilia , Matatula Marles Yohannis , Lekatompessy Felicia Miranda
Published: August 2024

The purpose of the study is to find out the EFL students’ perspective on the use of mind mapping as a cognitive activity in an academic writing class in the English education study program at Pattimura University. This study took 3 students (1 male and 2 females) from an English education study program. The In-depth interview is the instrument of data collection with qualitative as the research method. The result shows that the EFL students’ perceptions toward mind mapping seemed to have positive responses toward their language learning with several benefits based on their experience during academic writing class, such as the writing of students was more well-structured, increased students writing grades in academic writing and the beneficial using mind mapping made them becomes motivated in writing something. However, in the process, there were several difficulties that some students had to face when using this strategy such as they were to determine the sub-points and doing the mind mapping took more time, energy, and thoughts, and they were confused about where to start making a mind map. The study suggests that using mind mapping in writing classes, with proper support and training, can help students improve their writing skills. Encouraging its use in other subjects and adapting teaching based on feedback can make mind mapping a valuable tool for better learning and academic success. Keywords: Mind Mapping, Cognitive Tool, Academic Writing
Aplicação do modelo híbrido de ensino: um relato sob a perspectiva de professores de matemática
Authors: Pinheiro Karoline Reis , Amorim Neto Alcides de Castro
Published: August 2024

Considerando a realidade da pandemia e os seus impactos na educação, analisamos os acontecimentos que afetaram o processo de ensino e aprendizagem nesse cenário. Desse modo, realizamos observações e aplicamos questionários aos professores de matemática, com o intuito de entender seus conhecimentos sobre metodologias ativas e ensino híbrido, e suas percepções sobre a aplicação do modelo. Por meio dessa pesquisa, foi possível observar e relatar os fatos que ocorreram em uma escola pública de Manaus, como isso afetou a forma de ensinar matemática, como se deu a aplicação do modelo híbrido e as considerações dos professores em relação ao modelo. Portanto, através das observações feitas, verificamos que o modelo híbrido tem grande potencial agregador para a educação, desde que haja conhecimento sobre ele, suficiente para sua aplicação e utilização das ferramentas disponíveis para que seja eficaz o trabalho desenvolvido por professores e alunos.
Chayote (Sechium edule) as a Galactagogue: A Quasi-Experimental Study in Postpartum Women
Authors: Sa’idah Silfia Nuzulus , Desy Qomarasari  , Daris Yolanda Sari  , Endah Paridayanti
Published: August 2024

The establishment of successful breastfeeding is crucial for both maternal and infant health. However, many women experience challenges with milk production, leading to supplementation or early cessation of breastfeeding. Chayote (Sechium edule), a widely available and nutrient-rich vegetable, has been traditionally used to support lactation. This study aimed to investigate the effect of chayote consumption on breast milk production in postpartum women. A quasi-experimental, one-group pretest-posttest design was employed. Thirty-five postpartum women who reported concerns about milk supply were recruited. Participants consumed 600 grams of steamed chayote daily for seven days. Breast milk production was measured before and after the intervention using a standardized breast pump. Additionally, maternal perception of milk supply and infant weight gain were assessed. The mean breast milk production increased significantly from 315 ml (SD = 45) at baseline to 480 ml (SD = 55) after the intervention (p < 0.001). The majority of participants (82.9%) reported a perceived increase in milk supply. Infant weight gain also showed a positive trend, although not statistically significant. The consumption of chayote appears to be effective in enhancing breast milk production in postpartum women. This readily available and affordable dietary intervention may offer a valuable strategy to support lactation and promote breastfeeding success.
Alumni Engagement and Ordinary-Level Students' Academic Performance in Government-Aided Secondary Schools in Sheema Municipality
Authors: Kyorimpa Adrine , Aheisibwe Irene , Asiimire Donah
Published: August 2024

The study aimed to assess Alumni Engagement in ordinary-level students' Academic Performance in Government-aided Secondary Schools in Sheema municipality. The study employed a descriptive research design. The target population was 6 headteachers from 6 secondary schools, 92 teachers, 6 Alumni, Municipal Education Officer (MEO) and Municipal Inspector of Schools (MIS). A sample of 106 respondents was considered for the study from 6 Secondary schools. The study employed interviews and questionnaires as data collection methods. The study considered both qualitative and quantitative methods of data analysis. The study findings revealed that alumni engagement influences the postings and employment of teachers in specialised disciplines, organising training workshops and award ceremonies, developing mentoring avenues, organising inspirational talks, managing student discipline and conducting seminars with students. The study recommendations were the establishment of alumni-sponsored programmes aimed at collaboration with alumni networks to create mentorship programmes, diversification of alumni engagement activities beyond traditional events by leveraging technology, encouraging alumni participation in school improvement projects, such as infrastructure upgrades, and extracurricular activity support, to foster a sense of ownership and investment in the school's development
Hematopoietic and leukemic stem cells homeostasis: the role of bone marrow niche
Authors: Khattab Shaimaa , El Sorady Manal , El-Ghandour Ashraf , Visani Giuseppe , Piccaluga Pier Paolo
Published: August 2024

The bone marrow microenvironment (BMM) has highly specialized anatomical characteristics that provide a sanctuary place for hematopoietic stem cells (HSCs) that allow appropriate proliferation, maintenance, and self-renewal capacity. Several cell types contribute to the constitution and function of the bone marrow niche. Interestingly, uncovering the secrets of BMM and its interaction with HSCs in health paved the road for research aiming at better understanding the concept of leukemic stem cells (LSCs) and their altered niche. In fact, they share many signals that are responsible for interactions between LSCs and the bone marrow niche, due to several biological similarities between LSCs and HSCs. On the other hand, LSCs differ from HSCs in their abnormal activation of important signaling pathways that regulate survival, proliferation, drug resistance, invasion, and spread. Targeting these altered niches can help in better treatment choices for hematological malignancies and bone marrow disorders in general and acute myeloid leukemia (AML) in particular. Moreover, targeting those niches may help in decreasing the emergence of drug resistance and lower the relapse rate. In this article, the authors reviewed the most recent literature on bone marrow niches and their relations with either normal HSCs and AML cells/LSC, by focusing on pathogenetic and therapeutic implications.
Linierisasi Kepemimpinan Berdasarkan Pancasila dan Komitmen Pucuk Pimpinan dalam ISO 9001:2015
Authors: Riwayadi Eko , Bachri Syaiful , Affandi Merica Cahya
Published: August 2024

Manajemen organisasi sangat penting untuk ditata dengan baik dan memenuhi stndar internasional agar supaya organisasi bisa bersaing dan hasilnya bisa diterima secara global. ISO9001:2015 sebagai salah satu sistem manajemen mutu sangat perlu untuk di terapkan di organisasi supaya perusahaan bisa bersaing dan memenangkan persainagn secara internasional. Untuk menerapkan ISO 9001:2015 di organisasi diperlukan komitmen pemimpin yang sangat tinggi supaya sistem manajemen mutu itu berjalan dengan baik. Komitmen pemimpin memegang peranan yang sangat penting. Pemimpin yang menerapkan nilai-nilai Pancasila dengan baik terbukti berhasil dalam menjalankan kepemimpinannya, hal ini berarti pemimpin yang menerapkan nilai-nilai Pancasila adalah pemimpin yang berkomitment terhadap suksesnya organisasi. Penelitian ini bertujuan untuk mengetahui hubungan antara pemimpin yang memahami dan melaksanakan Strategi Manajemen Pancasila terhadap suksesnya implementasi ISO 9001:2015 di organisasi. Metode yang digunakan dalam penelitian ini adalah metode studi literatur terhadap buku, internasional standar dan artikel ilmiah. Penelitian ini menemukan matriks hubungan antara komitmen pemimpin yang di jiwai nilai-nilai Pancasila dengan hasil implementasi ISO 9001:2015.
Organizational management is very important to be well organized and comply with international standards, to gain competitive results and accepted globally. As a quality management system, ISO9001:2015 is very important to be implemented to differentiate the organization from international competition, in which such implementation is required a very high leadership commitment to function well of the quality management system. Leadership commitment plays a very important role. Leaders who apply Pancasila values have been proven to be able to successfully execute their leadership, which means that leaders who apply Pancasila values are committed to the success of the organization. This study aims to determine the relationship between leaders who understand and implement Pancasila's strategic management to successfully implement ISO 9001:2015 in their organizations. The method used in this research is to study the literature in books, international standards and scientific articles. This study found a matrix of the relationship between the commitment of leaders inspired by Pancasila's values and the results of the implementation of ISO 9001:2015
Kinerja Keuangan dalam Mempengaruhi Return Saham Perusahaan LQ45 di Bursa Efek Indonesia
Authors: Habibah Umi , Heruwanto Joni
Published: August 2024

Penelitian untuk mengetahui pengaruh kinerja keuangan yang diproksi melalui current ratio (CR), return on aset (ROA), debt to equity ratio (DER), dan total aset turn over  (TATO) terhadap Return Saham perusahaan LQ45 di Bursa Efek Indonesia. Penelitian menggunakan sampling jenuh yaitu semua perusahaan LQ45 tahun 2019 yang terdaftar di Bursa Efek Indonesia. Analisis yang digunakan adalah regresi linear ganda. Current ratio berpengaruh terhadap return saham. Return on assets, debt to equity ratio dan total assets turn over tidak berpengaruh terhadap return saham.
Research to determine the effect of financial performance proxied through current ratio (CR), return on assets (ROA), debt to equity ratio (DER), and total asset turn over (TATO) on the Return of LQ45 company shares on the Indonesia Stock Exchange. The study used saturated sampling, namely all LQ45 companies in 2019 listed on the Indonesia Stock Exchange. The analysis used is multiple linear regression. The current ratio affects stock returns. Return on assets, debt to equity ratio and total assets turn over have no effect on stock returns.
Kepuasan Konsumen: Tinjauan Faktor Anteseden Diskon Pengerjaan, Kualitas Pelayanan dan Kualitas Produk
Authors: Arianto Wahyu , Irfal Irfal
Published: August 2024

Kenyaman rumah penting bagi setiap orang. Solusi interior sebagai penyedia jasa konstruksi interior sangat memperhatikan kepuasan konsumennya. Penelitian ini akan mendalami mengenai diskon pengerjaan, kualitas pelayanan dan kualitas produk terhadap kepuasan konsumen. Studi ini melibatkan sebanyak 100 responden yang pernah melakukan pembelian produk Solusi Interior. Data yang sudah terkumpul diolah dan dianalisis menggunakan model persamaan struktural structural. Penelitian menghasilkan temuan terdapatnya pengaruh diskon pengerjaan terhadap kepuasan konsumen dengan arah positif sebesar 0,689. Terdapat pengaruh kualitas pelayanan terhadap kepuasan konsumen dengan arah positif sebesar 0,799. Terdapat pengaruh kualitas produk terhadap kepuasan konsumen dengan arah positif sebesar 0,797.
The comfort of home is important for everyone. Interior solutions as an interior construction service provider are very concerned about customer satisfaction. This research will explore workmanship discounts, service quality and product quality on consumer satisfaction. This study involved as many as 100 respondents who had made a purchase of Interior Solutions products. The collected data is processed and analyzed using structural equation models. The result of this study is the effect of workmanship discounts on consumer satisfaction with a positive direction of 0.689. There is an influence of service quality on customer satisfaction with a positive direction of 0.799. There is an influence of product quality on consumer satisfaction with a positive direction of 0.797.
Komitmen dan Disiplin Diri serta Iklim Organisasi sebagai Faktor Pendorong Kinerja Pegawai
Authors: Masroh Masroh , Sapruwan Muhammad
Published: August 2024

Kenerja pegawai ditentukan oleh aspek perilaku kerja diantaranya  komitmen dan disiplin diri serta iklim organisasi. Penelitian ini merupakan penelitian inferensial yang berupaya menguji pengaruh  komitmen dan disiplin diri serta iklim organisasi terhadap kinerja pegawai. Penelitian dilakukan di kantor Bappedalitbang Kabupaten Bogor dengan menyebarkan kuesiner kepada 70 pegawai sebagai responden penelitian. Analisis deskriptif kuantitatif dan regresi liner berganda digunakan sebagai alat analisis. Penelitian menghasilkan model yang layak dimana komitmen diri tidak signifikan terhadap kinerja pegawai. Disiplin diri positif pengaruhnya terhadap kinerja pegawai. Iklim organisasi positif pengaruhnya terhadap kinerja pegawai.
Employee performance is determined by aspects of work behavior including self-commitment; self-discipline and organizational climate. This research is inferential research which seeks to examine the influence of commitment and self-discipline as well as organizational climate on employee performance. The research was conducted at the Bogor Regency Bappedalitbang office by distributing questionnaires to 70 employees as research respondents. Quantitative descriptive analysis and multiple linear regression are used as analytical tools. The research produces a feasible model where self-commitment is not significant to employee performance. Self-discipline has a positive effect on employee performance. Organizational climate has a positive influence on employee performance.
The Effect of Compensation and Rewards on Job Satisfaction through Punishment as an Intervening Variable
Authors: Rahadi Dedi Rianto , Prastiani Elsadai Dwi , Fajri Faizah Meyliana , Alfinandita Intan Maya Zena
Published: August 2024

This study aims to analyze the effect of compensation and rewards on job satisfaction throughpunishment as an intervening variable. This research applies the Structural Equation Modeling (SEM) - Partial Least Squares (PLS) analysis technique using the Smart PLS Version 3 tool in processing data obtained through distributing questionnaires to 314 employees of PT Suka Sukaku. The results showed that punishment has no significant effect on job satisfaction, giving fair awards has a positive impact on employee job satisfaction, compensation has a significant effect on job satisfaction, compensation has a significant effect on punishment, awards have a significant effect on job satisfaction, compensation has a significant effect on job satisfaction through punishment and awards have a significant effect on job satisfaction through punishment
The Dividend Payment Puzzle
Authors: Fauziah Fenty , Jamal Sri Wahyuni , Rashid Umi Kartini
Published: August 2024

This study's objective is to ascertain and identify influencing the decision to pay dividends.  Dividend data were subjected to fixed effects model. Panel regression analysis taken from annual reports issued by manufacturing companies listed on the BEI above 2016-2022 period. The affect dividends are ROA, DER, Size and TR.  The company must pay attention to the overall factor that used, so that policies can be taken appropriately. Dividend payments are concentrated in large companies. Managers can use the empirical findings to make dividend payment decisions. The government learn from the impact of changes to the Job Creation Law and Income Tax Law, so that Indonesia becomes an investment destination.  The dividend puzzle needs close attention to the different characteristics of firms in explanations for paying dividends.
Making (A)mends
Authors: Pelsmakers Sofie , Miettinen Mari-Sohvi , Castaño-Rosa Raúl , Kolkwitz Mario , Kalakoski Iida
Published: August 2024

In October 2022, the 14th ATUT symposium Making (A)mends was held at the Tampere School of Architecture. Making (A)mends plays on the word ‘mend’ and to ‘amend’; to mend in the sense of repairing or restoring something, but also in the sense of redeveloping and putting something back together. ‘Amending’ is about improving, changing, adapting, and putting ourselves on a new path.
At the time of the conference, we had just come out of a two-year COVID pandemic of lockdowns and little face to face contact. It made visible the positive impact we have on each other and that we need each other as fellow human beings, but it also became visible – when we slowed down and gave back the city to nature – how nature and non-humans were able to take up that space. For a short time, we could glimpse a different kind of planet.
Yet climate records continue to be broken around the world: hottest temperatures, longest heatwaves, worst droughts ever recorded; extreme and record flooding and rainfall. And we are guilty of contributing to this: architecture and built environment projects continue to exploit, disrupt and damage the planet.
We also witnessed war and conflict, and this showed how we are deeply interconnected as humans to each other but also to our environment. It shows that a better, more sustainable, inclusive and restorative world is not possible without peace.
Fixing the climate, biodiversity and security crises we face as a society are extraordinarily complex and challenging tasks. Research has shown that radical transformations of our physical, political, organisational, social and value structures are needed to respond to – and prepare for – these crises and to restore the past damage that our activities and (in)activities in the built environment have inflicted. Architecture and urban planning have a fundamental role to play in this, given the long ‘lock-in’ of the urban plans and spaces and places we are part of designing and their potential (negative and positive) impacts over time with the associated local and global (in)justices they create. 
This special issue provides several different perspectives on ‘Making (A)mends’ to address how we can and must be part of the solution and raises at times uncomfortable questions about our own role, responsibility and values as architects and urban planners, how we got here, and how we can make (a)mends, urgently.
Building Management Systems in residential buildings: their role in energy and indoor climate resilience
Authors: Castaño-Rosa Raúl , Pelsmakers Sofie , Wang Junqi , Cao Shi-jie
Published: August 2024

The building sector contributes to around 39% of the global carbon emissions, and the operation of buildings, and especially residential buildings, is a large contributor. Hence tackling the efficient operation and maintenance of residential buildings is an effective way to reduce energy consumption and carbon emissions and hence contribute to climate resilience. While the operation and maintenance phases of non-residential buildings generally rely on Building Management Systems (BMS), BMS are typically absent in standard housing; instead, residents manage their own homes individually. Through a scoping literature review, this paper investigates the potential of BMS in promoting energy efficiency, indoor climate comfort and long-term resilience (e.g., managing cold periods and heatwaves), and general suitability for the residential environment. Findings show that promoting resilience in residential buildings through the implementation of BMS is not explicitly investigated in the existing literature, instead the focus is on promoting energy efficiency, innovation and climate change mitigation. Furthermore, main BMS are designed based on solely technical parameters, neglecting social and human factors. This study therefore argues for the need to adopt a human-centred design approach to include key aspects of adaptability, flexibility, equity and inclusivity in the design and implementation of BMS in residential buildings. In the end, this paper contributes key aspects for BMS to promote resilience in residential buildings.
Rewilding the built environment: a resilient response to different crises
Authors: Castaño-Rosa Raúl , Pelsmakers Sofie , Järventausta Heini
Published: August 2024

Society continues to face many crises, from climate change, loss of biodiversity and air pollution to the pandemic, with associated impacts to human health and wellbeing. The built environment plays an important role in both mitigating and adapting to these impacts and in safe-guarding citizens. The presence and access to green spaces in the built environment plays a fundamental role in citizen’s ability to cope with adversity of different kinds and scale, while in itself supporting biodiversity. This paper aims to (1) synthesize knowledge about the diverse role that green spaces, and by extension the rewilding of our built environment, play as part of a resilient society and built environment and (2) the specific conditions and characteristics of green spaces and the built environments to maximize their benefits, while avoiding unintended consequences. This is done through a systematic literature review to present existing knowledge about the role of green spaces in a resilient built environment and society, followed by a qualitative content analysis that identifies the conditions and characteristics of green spaces as resilient solutions. Findings highlight the importance of the diversity of green space provision in type (e.g., ecological corridors), scale (e.g., community gardens, green roofs and walls), and location (e.g., parks, forests), and that they can support social inclusivity, community resilience and wellbeing. Furthermore, findings highlight that green spaces need to be designed in such a way that they (1) support biodiversity, (2) are interconnected with the context, (3) accessible and (4) appealing for citizens to protect and appreciate them.
Material flows from buildings
Authors: Kolkwitz Mario , Huuhka Satu
Published: August 2024

In the circular economy, building stocks are valuable urban mines of secondary resources and reserves of space whose utilization has the potential to substitute for virgin resources. The purpose of this study is to compare patterns in construction (inflows) and demolition (outflows) and how they shaped the building stock in two Finnish cities, Vantaa and Tampere between 2000 and 2018. By attributing flows to distinct urban development patterns (such as greenfield, replacement, infill, etc.) and investigating population and labour force structure, the goal is to recognize differences and similarities between the case studies. In doing so, the aim is to understand how a comparative approach may help to identify drivers and patterns in the building stock dynamics of the two cities which further aids the development of a circular building stock management. The methodological foundation for this research is Urban Metabolism in form of Material Flow Analysis with a focus on the product i.e., building level but also space as a service provided by buildings. Tampere and Vantaa are the third and fourth largest cities in Finland, with a population of circa 230,000 each. Despite their similar sizes, differences in their geographical properties, contexts, and roles in Finland make them interesting targets for comparative research.
The results show that growth in population and labour force led to a substantial increase in both cities’ building stocks. While Vantaa’s more rural character allowed a higher amount of sprawl by loose-built housing typologies, geographical restrictions and the already dense building stock in Tampere often led to more compact housing and an overall higher amount of demolition in relation to construction. The development of both non-residential building stocks shows a clear tendency towards typologies that support respective economic operations. Alas, material intensity coefficients, which would enable quantifying the material and CO2 impacts of these developments, do not yet exist for Finnish building typologies. Nevertheless, this study’s findings provide a preliminary understanding of how different mechanisms of urban development, such as construction and demolition, shape environmental strains and support the development of pinpoint circular strategies.