bluuebunny/crossref_metadata_2025 huggingface dataset:
Kesetaraan Gender dalam Agama-Agama: Analisis Filsafat Taoisme-Islam Sachiko Murata
Authors: Kumari Fatrawati
Published: March 2023

Kesetaraan gender yang menempatkan perempuan dan laki-laki secara sejajar belum sepenuhnya dapat dilaksanakan. Penyebabnya selain karena alasan sosial-budaya, juga terdapat alasan teologis, dimana agama dianggap turut berkontribusi melanggengkan ketidakadilan gender dengan melegitimasi perlakuan yang merugikan perempuan melalui bahasa agama. Namun ketika agama ditelusuri lebih dalam lagi, ternyata anggapan tersebut terbantahkan, karena semua agama mengajarkan prinsip kesetaraan gender. Agama menunjukkan jati dirinya sebagai penyambung suara Tuhan dalam mengangkat harkat dan derajat manusia di muka bumi, tak terkecuali perempuan. Untuk mengetahui bagaimana agama-agama memaknai kesetaraan gender, perlu kajian khusus dengan menggunakan pendekatan filsafat Taoisme-Islam Sachiko Murata. Tujuannya adalah agar memperoleh gambaran filosofis-spiritual mengenai kesetaraan gender sebagaimana inti ajaran agama-agama yang dalam hal meliputi agama: Kristen, Yahudi, Hindu, Budha dan Islam.Kata Kunci: Kesetaraan, Gender, Agama, Filsafat Taoisme-Islam
Analysis of genetic variability and character relationship in rice (Oryza sativa L.) seed and seedling traits
Authors:   Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Hoque N. , Islam Z. , Zarin F. , Mahmud N. , Rahman M. , Biswas B.
Published: March 2023

Eight rice genotypes with different genetic backgrounds were evaluated for grain length, grain width, grain length width ratio, grain thickness, 1000 grain weight, seed germination percent, shoot length, root length and root shoot ratio. The genetic variance (δ^2 g), phenotypic variance (δ^2 p), phenotypic covariance (PCV), genotypic coefficient of variation (GCV), heritability (h_b^2), genetic advance (GA), genetic advance in percent of mean (GA %) and correlation coefficient were all calculated. The experiment was conducted using a Randomized Block Design with three replications in a controlled environment in the laboratory of Department of Agriculture at Bangabandhu Sheikh Mujibur Rahman Science and Technology University Gopalganj in June 2021. For all of the studied characters, analysis of variance revealed a significant difference in genotypes. PCV values greater than GCV were found in all of the characteristics, indicating that they were influenced by non-additive gene action rather than environmental factors and that selection for improving these traits would be beneficial. The PCV (41.33) and GCV (41.70) estimates for the root shoot ratio were both high, indicating a wide range of variability for the two component characteristics, shoot length and root length. PCV and GCV values were moderate for grain length width ratio, seed germination percent, shoot length, and root length. The PCV and GCV of most grain characters were low. All of the characters had high heritability, ranging from 90.77 percent to 99.81 percent, except for 1000 grain weight (46.91 percent). Seed germination percent (36.03), shoot length (40.03), root length (35.16) and root shoot ratio (35.16) all had high heritability and high genetic advance in percent of mean (79.25). Grain thickness (8.68) and seed germination percent had the lowest GA% (8.71). Grain length with grain length width ratio, grain width with root shoot ratio, 1000 grain weight with grain width, grain thickness, root length and root shoot ratio were all found to have positive and significant correlations in a character association study. At the genotypic level, the highest positive significant correlation was found between 1000 grain weight and root shoot ratio (r_g= 0.908) and grain length and grain width ratio (r_p=0.900). According to genetic variability and correlation analysis, grain length, grain length width ratio, 1000 grain weight, root length and root shoot ratio could be used as selection indices for further improvement of seed and seedling characters of rice genotypes.
Analisis Model Epidemi SEIR Menggunakan Metode Runge-Kutta Orde 4 pada Penyebaran COVID-19 di Indonesia
Authors: Rahmadhani Anis Putri , Kusumastuti Ari , Juhari Juhari
Published: March 2023

This study discusses the analysis of the Susceptible-Exposed-Infected-Recovered (SEIR) epidemic model using the fourth-order Runge-Kutta method on the spread of COVID-19 in Indonesia by taking into account the factors limiting community interaction and the percentage of vaccination as model parameters. The purpose of this study was to determine the application of the Susceptible–Exposed–Infected–Recovered (SEIR) model using the fourth-order Runge-Kutta method in dealing with COVID-19 in Indonesia. The steps in analyzing the model are to determine the stability of the model that produces local asymptotic stability, then carry out the implementation as well as simulation using the fourth-order Runge-Kuta method in dealing with COVID-19 in Indonesia. The calculation results show the effect of limiting community interaction and vaccination in reducing cases of COVID-19 infection. Where, when limiting public interaction, the number of cases of COVID-19 infection is lower than before the restrictions on community interaction were carried out, and the higher percentage of vaccinations also resulted in more sloping infection cases. This study provides information that if restrictions on community interaction continue to be carried out by continuing to increase the percentage of vaccinations, it is estimated that the daily graph of positive cases of COVID-19 will be increasingly sloping and close to zero. Thus, the addition of new cases will decrease and it is hoped that the COVID-19 pandemic will end soon.
Analisis Dinamik Model Infeksi Mikrobakterium Tuberkulosis Dengan Dua Lokasi Pengobatan
Authors: KT Ummul Aulia , Widayani Heni , Kusumastuti Ari
Published: March 2023

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. The disease is considered dangerous because it infects the lungs and other organs of the body and can lead to death. This study discusses a mathematical model for the spread of tuberculosis with two treatment sites as an effort to reduce the transmission rate of TB cases. Treatment for TB patients can be done at home and in hospitals. The purpose of this study was to construct a mathematical model and analyze the qualitative behavior of the TB spread model. The construction of the model uses the SEIR epidemic model which is divided into five subpopulations, namely susceptible subpopulations, latent subpopulations, infected subpopulations receiving treatment at home, and infected subpopulations receiving treatment at the hospital, and cured subpopulations. The analysis of qualitative behavior in the model includes determining the local and global equilibrium and stability points. The results of the analysis shows that the model has two equilibrium points, namely a disease-free equilibrium point and the endemic equilibrium point. The existence of endemic equilibrium point and the local and global stability of the two equilibrium points depend on the basic reproduction number denoted by . If ,  there is only disease-free equilibrium point. If , there are two equilibrium points, namely the disease-free equilibrium point and the endemic equilibrium point. Stability analysis shows that the disease-free equilibrium point is locally and globally asymptotically stable if . While, if , the endemic equilibrium point will be asymptotically stable locally and globally.
Agroecological Transition in the Cotton Zone: Analysis of Technical-Economic and Environmental Performances in Northern Benin - A Literature Review
Authors: Abou Chabi Abdou Ganiou , Tovignan Silvère , Yabi Jacob Afouda
Published: March 2023

This article is a systematic review of the knowledge of technical-economic and environmental performance in agroecological transition. The data collected in the Scopus and dimension database concerned exclusively published articles and journals, using the relevant terms. Thus, 227 documents exported from Scopus and dimension were submitted to a bibliometric analysis with the Citespace software, then the inclusion and exclusion criteria were carried out according to the ROSES standards.  The results reveal that the annual production of studies related to the technical-economic and environmental performance in agro-ecological transition is increasing with an annual growth rate of about 1.3%.  There is a common understanding of agroecological transition. The agroecological transition addresses the problems of the food system from field to plate, covering all activities and actors involved in the cultivation based on natural resources. Among the agroecological practices analyzed, the application of compost seems the most promising to be scaled up to improve economic and environmental performance.
Risk of Complications in Patients Undergoing Complete Thyroidectomy. A Retrospective Study
Authors: Kokalari Igli , Shundi Lila , Abazaj Erjona , Ali Ela , Nikolla Ledina
Published: March 2023

Introduction: The main aim of this study was to determine the influence of surgery on postoperative complications in patients undergoing total thyroidectomy. Methods: Patients diagnosed with goiter and undergoing total thyroidectomy for more than ten years were retrospectively enrolled, and the main study outcomes were postoperative complications. Statistical analysis was done by chi-square and t-test with a p-value <0.05 as significant. Results: A total of 116 patients with goiter were identified (mean age, 45.3 ± 8.75 years, with minimum and maximum age of 23 to 69). The most affected age with goiter resulted in 41-50 years old with 41.4% (95% CI, 37.4 to 45.8%). The majority of patients with goiter were women (85.3%), with a mean age of 47 years. After the thyroid surgery, male patients had significantly higher rates of hospital readmission than females with a risk ratio [RR] of 1.05; 95% CI [0.67–1.52], p-value = 0.02. Either hemorrhage/hematoma occurred in 4.7% and cardiopulmonary and thromboembolic events in 3.1% of the patients undergoing total thyroidectomy. In addition, either hypoparathyroidism was observed in 3.1% and temporary recurrent laryngeal nerve palsy (RLN) in 1.56%. Conclusion: The current study demonstrates that total thyroidectomy is associated with an increased rate of hemorrhagic complications. RLN palsies and hypoparathyroidism are less observed. Male patients undergoing thyroidectomy have higher rates of readmission and ICU admission. Furthermore, male patients revealed higher rates of hemorrhage and wound infection, while hypoparathyroidism or temporary recurrent laryngeal nerve palsy was more frequent among female patients.
Temas de contratación con el Estado. Perspectiva jurídica
Authors: Soria Aguilar Alfredo F
Published: March 2023

En el Perú, la contratación pública se rige por un amplio número de reglas y procedimientos técnicos y sumamente complejos de entender. Para facilitar esta labor, presentamos el libro Temas de contratación con el Estado. Perspectiva jurídica, un texto de consulta especializado en las diversas fases de la contratación con el Estado peruano, reguladas por el Texto Único Ordenado (TUO) de la Ley 30225.
Traducir derechos, traducir culturas. Entre el castellano y las lenguas originarias del Perú
Authors: Andrade Ciudad Luis , de Pedro Ricoy Raquel , Howard Rosaleen
Published: March 2023

Este libro reúne nueve estudios que ofrecen una visión contemporánea de lo que significa traducir e interpretar entre el castellano y las lenguas originarias en el Perú. Los textos abordan la experiencia de los traductores-intérpretes indígenas, los retos y dificultades que ellos y ellas atraviesan al traducir a sus lenguas el discurso legal, así como al mediar entre el Estado y los pueblos originarios.
Pratiques émergentes pour la mobilisation des hommes et des garçons dans le secteur de l’EAH
Authors: Bongomin Godfrey , Huggett Chelsea , Jain Juhi , Lala Sunetra
Published: March 2023

Ce document accompagne le numéro d’Aux Frontières de l’assainissement : Mobiliser les hommes et les garçons pour un secteur EAH porteur de transformation en matière de genre, 2e partie, qui explore dans quelle mesure la mobilisation des hommes et des garçons dans les processus EAH peut être porteuse de transformation dans les rôles et les attitudes en matière de genre et d’un changement durable afin de réduire les inégalités de genre entre les ménages, les communautés, les organisations et les politiques. Les exemples pratiques présentés ici proviennent d’Ouganda, de Zambie, du Timor oriental, de Papouasie-Nouvelle-Guinée (PNG), des îles Salomon, du Bangladesh, d’Inde, d’Indonésie, de Vanuatu et du Népal. Chacun de ces exemples, qui sont tous issus de projets financés par le Water for Women Fund du gouvernement australien, décrit des interventions qui emploient différentes approches porteuses de transformation en matière de genre pour mobiliser et sensibiliser les hommes et les garçons. Chacun explique également les succès obtenus et les défis rencontrés dans le cadre des projets.
Prática emergente para envolver homens e rapazes em WASH
Authors: Bongomin Godfrey , Huggett Chelsea , Jain Juhi , Lala Sunetra
Published: March 2023

Este documento acompanha Fronteiras do Saneamento: Envolver homens e rapazes em WASH transformador de género, 2ª Parte, que analisa até que ponto o envolvimento de homens e rapazes nos processos de WASH está a produzir mudanças transformadoras nos papéis de género e nas atitudes, e mudanças sustentáveis na redução das desigualdades de género nas famílias, comunidades, organizações e políticas. São aqui apresentados exemplos práticos do Uganda, Zâmbia, Timor-Leste, Papua Nova Guiné, Ilhas Salomão, Bangladexe, Índia, Indonésia, Vanuatu e Nepal. Cada um destes exemplos, todos eles de projectos financiados pelo fundo Water for Women do governo australiano, descreve intervenções que utilizaram diferentes abordagens transformadoras de género para chegar a homens e rapazes e os levar a participar. Os exemplos descrevem também os êxitos e os desafios dos projectos.
Development of a Moderation-Based Islamic Education Learning Model in Efforts to Strengthen Student Tolerance at Public Universities in Lampung and Banten Provinces
Authors: Imam Syafei  , Wasehudin  , M. Asy'ari  , Rofiqi  , Cicik Aini
Published: March 2023

Perguruan tinggi sebagai pelaksana pendidikan memiliki tanggungjawab moral dalam rangka membentuk masyarakat yang moderat dalam upaya memperkuat sikap toleransi mahasiswa melalui model pembelajaran yang dilaksanakan. Penelitian ini berupaya untuk menungkap dan menganalisis pengembangan model pembelajaran PAI berbasis moderasi beragama dalam upaya memperkuat toleransi mahasiswa di Perguruan Tinggi Umum di Provinsi Lampung dan Banten. Metode penelitian yang digunakan dalam kajian ini adalah desain research and development, yaitu penelitian yang digunakan untuk menghasilkan produk tertentu dan menguji keefektifan produk tersebut berdasarkan prosedur yang dilaksanakan dari tahapan perencanaan, pengembangan, uji coba, revisi, dan pelaksanaan produk yang berupa model pembelajaran PAI. Model pembelajaran yang dikembangkan adalah model pembelajaran PAI dengan small group discussion di mana mahasiswa dituntut untuk mendiskusikan  tema tentang moderasi serta memecahkan persoalan tertentu berkaitan dengan moderasi. Hasil penelitian ini menunjukkan bahwa pembelajaran PAI berbasis moderasi memiliki peran yang besar terdahap pembentukan sikap toleransi mahasiswa di Perguruan Tinggi Umum di Provinsi Lampung dan Banten. Pembelajaran PAI berbasis pada moderasi beragama memiliki komitmen kuat di dalam menanamkan nilai multikultural kepada mahaisiswa sehingga mereka dapat menghormati peredaan yang terjadi dalam lingkungan masyarakat. Hasil dari Pengembangan Model Pembelajaran PAI Berbasis Moderasi Beragama mahasiswa manunjukkan bahwa  model pembelajaran PAI dapat meningkatkan sikap toleransi beragama mahasiswa secara signifikan. Oleh karena itu, pengembangan model pembelajaran tersebut sangat direkomendasikan untuk diaplikasikan dalam konteks perguruan tinggi umum khususnya di  Provinsi Lampung dan Banten sebab memiki kontribusi kuat dalam rangka mencetak mahasiswa yang memiliki sikap toleransi yang tinggi.
Perencanaan Penggunaan Lahan Untuk Pengembangan Budidaya Tembakau di Kabupaten Temanggung
Authors: Prasetyo Rahadian Adi , Mulyawan Ronny
Published: March 2023

Tobacco is one of the importan commodities in Temanggung Regency. Temanggung’s tobacco has a nicotine content from 3 – 8%, so it is used as one of the main flavoring ingredients in manufacture of cole cigarettes. The rapid development of tobacco cultivation land in Temanggung Regency was not followed by site selection according to land capability class and land suitability. The aim of this study were to, 1) calculate the aviability of land for the development of tobacco cultivation, 2) determine the land suitability class for tobacco cultivation. The matching method is use in land suitability class. Extensification of tobacco cultivation land in temanggung regency can be carrie out on land with suitability class S3 (according to marginal) covering an area of 17.490,90 ha, covering a dry area of 11.975 ha; rainfed rice fields 3.622,9 ha; and shurbs 1.893 ha . Actual land suitability class of land aviable, among others S3na (8.293,98 ha), S3nr,na (3.621,96 ha), S3rc,na (2.389,78 ha), S3tc,nr,na (1.014,93 ha), S3tc,na (787,04 ha), S3tc (402,73 ha), S3tc,nr (343,43 ha), and S3tc,rc (1,17 ha). Potential land suitability class of land aviable, among others S2na (8.293,98 ha), S2nr,na (3.621,96 ha), S3tc (2.548,13 ha), S3rc (2.389,78 ha), and S3tc,rc (1.17 ha).
Optimalisasi Kompetensi Guru SD Melalui E-Book Berbasis Pertanian Lokal di Jember
Authors: Fitriyah Chumi Zahroul , Puspitaningrum Dyah Ayu , Finali Zetti , Hutama Fajar Surya
Published: March 2023

Jenis penelitian ini adalah penelitian pengembangan yang bertujuan untuk mengembangkan sebuah produk dalam bentuk e-book. Model yang digunakan dalam penelitian ini adalah model Borg and Ball yang terdiri dari 7 tahap, yaitu (1) tahap analisis kebutuhan; (2) tahap perancangan dan desain produk; (3) tahap produksi atau pelaksanaan pengembangan produk awal; (4) tahap validasi awal; (5) tahap revisi produk; (6) tahap uji coba produk; dan (7) tahap revisi dan penyebaran. Penelitian ini dilakukan di SDN Jember Lor 05 kelas IVA dan IVB. Hasil validasi dari keduanya mendapat skor sebesar 90, 8 yang termasuk dalam kategori sangat layak. Selainjutnya dilakukan uji kelompok kecil dengan memperoleh skor di atas 80%, dan dinyatakan tidak ada revisi. Penghitungan tes hasil belajar peserta didik memperoleh persentase sebesar 82,93%. Hasil angket respon siswa diperoleh hasil sebesar sebesar 90,08, sehingga termasuk kategori sangat baik.
Évaluation socio-économique de la réduction d’usage des antibiotiques dans la filière porcine : le plan Ecoantibio 1
Authors: LHERMIE Guillaume , FERCHIOU Ahmed , NDIAYE Youba , JUSTINIA Giffona , LISBONA Damien , KORALEWSKI Mathilde , DARDELET Line , WARET-SKZUTA Agnès , RABOISSON Didier
Published: March 2023

La contribution relative de l’usage des antibiotiques en production animale sur la baisse de l’efficacité des antibiotiques utilisés en médecine humaine reste mal documentée, mais l’importance de ce problème de santé publique requiert de réduire leur usage. Le plan Ecoantibio 1, mis en œuvre entre 2012 et 2016, consiste en une approche volontaire coordonnée par le Ministère de l’Agriculture afin de limiter l’usage des antibiotiques dans les filières d’élevage. Ce plan, ainsi que l’ensemble des initiatives privées et publiques mises en place sur cette période ont permis une réduction massive de l’usage des antibiotiques. L’évaluation rétrospective présentée ici identifie les effets socio-économiques, aux niveaux individuels et structurels, de ce plan sur la filière porcine française, perçue comme forte utilisatrice d’antibiotiques. Pour ce faire, une enquête a été conduite auprès des parties prenantes.
Les impacts socio-économiques du plan Ecoantibio 1 apparaissent modérés, au niveau des changements de pratiques, des transformations structurelles, et des effets économiques. Ce plan s’est inséré dans une dynamique professionnelle, amorcée par d’autres politiques publiques et des initiatives privées.  D’un point de vue technique, la plupart des alternatives aux antibiotiques existaient avant la mise en œuvre du plan, comme la vaccination ou la biosécurité. Les relations entre parties prenantes de la filière porcine ont été soit peu impactées, soit renforcées. Enfin, ce plan n’a pas eu d’impact significatif sur la croissance des porcs ni sur les revenus des différents acteurs. In fine, le plan Ecoantibio 1 est venu confirmer la dynamique déjà à l’œuvre, tout en donnant une assise règlementaire à des pratiques déjà en place.
Contemporary Chinese Queer Performance
Authors: Cao Siyang
Published: March 2023

Review of the book Contemporary Chinese Queer Performance, by Hongwei Bao.
Light Deflection by Traversable Wormhole in a Curvature-Coupled Antisymmetric Background Field
Authors: Javed Wajiha , Zahra Touqeer , C. Pantig Reggie , Övgün Ali
Published: March 2023

This paper is devoted to study the gravitational lensing for Curvature-coupled antisymmetric wormhole solution to compute the bending angle of light by utilizing the Gibbons and Werner technique. To achieve this, we find the Gaussian optical curvature and then apply Gauss-Bonnet theorem in the weak field limits. We also study the effects of plasma as well as dark matter mediums on the bending angle. Moreover, we analyze the graphical behaviour of the deflection angle $\alpha$ with respect to the impact parameter $\sigma$ and minimal radius $r_{0}$ in non-plasma and plasma mediums. We examine that deflection angle shows direct relation with $r_{0}$ such that large values of $r_{0}$ gives large deflection angle and small values of $r_{0}$ gives small deflection angle. For impact parameter $\sigma$, deflection angle $\alpha$ shows inverse relation. Additionally, we derive the deflection angle of light by using Keeton and Petters method and compare with the previous results.
A Bridge to Nowhere: Enabling Autonomy in a Case of Failed ECMO Rescue of Bleomycin Induced Pulmonary Toxicity
Authors: Hall James , Khilkin Michael , Murphy Sara , Botros George
Published: March 2023

Extracorporeal membrane oxygenation (ECMO) can be a life-saving intervention in cases of potentially reversible refractory respiratory failure. One such indication can be bleomycin-induced lung injury. However, in some cases, the injury can be so severe that it becomes irreversible and creates complex medical decisions regarding life support and the continuation of care when no additional therapeutic options are feasible, particularly in cases of patients who were young and fully functional prior to an acute illness. In cases of full pulmonary replacement with mechanical support and the degree of functionality that can be attained utilizing modalities such as ECMO can obscure the true severity of illness and make end-of-life decisions significantly harder for families and caregivers.
Traveling Wave Solutions of Fractional Differential Equations Arising in Warm Plasma
Authors: Ghode Krishna , Takale Kalyanrao , Gaikwad Shrikisan
Published: March 2023

This paper aims to study the fractional differential systems arising in warm plasma, which exhibits traveling wave-type solutions. Time-fractional Korteweg-De Vries (KdV) and time-fractional Kawahara equations are used to analyze cold collision-free plasma, which exhibits magnet-acoustic waves and shock wave formation respectively. The decomposition method is used to solve the proposed equations. Also, the convergence and uniqueness of the obtained solution are discussed. To illuminate the effectiveness of the presented method, the solutions of these equations are obtained and compared with the exact solution. Furthermore, solutions are obtained for different values of time-fractional order and represented graphically.
Existence of Fixed Points for Expansive Mappings in Complete Strong Altering JS-metric space
Authors: VARUNNYA X. M. JEFFIN , GNANACHANDRA P. , ANANDAPRIYA B.
Published: March 2023

The paper aims at initiating and exploring the concept of extended metric known as the Strong Altering JS-metric, a stronger version of the Altering JS-metric. The interrelation of Strong Altering JS-metric with the b-metric and dislocated metric has been analyzed and some examples have been provided. Certain theorems on fixed points for expansive self-mappings in the setting of complete Strong Altering JS-metric space have also been discussed.
Numerical Simulation of the Fracture Propagation Mechanism during Supercritical Carbon Dioxide Fracturing in Shale Reservoirs
Authors: Li Fengxia , Zhou Tong , Wang Haibo , He Jianming , Shi Aiping
Published: March 2023

To investigate the fracture propagation mechanism during supercritical CO2 fracturing in shale reservoirs, a numerical model was proposed based on the displacement discontinuity method. The Peng–Robinson equation was introduced to determine the variations in CO2 properties during the fracturing process. Considering natural fracture distribution in shale reservoirs, the fracture propagation mechanisms during supercritical CO2 fracturing in shale reservoirs under different horizontal stress differences and matrix permeabilities were analyzed. The influence of the proportion of CO2 preenergizing on fracture morphology was discussed. The results obtained via numerical simulation show that supercritical CO2 is beneficial to create a more complex fracture network by activating natural fractures under the same horizontal stress difference. CO2 easily penetrates into the matrix near the fracture surfaces, increasing reservoir energy. However, when the permeability of shale reservoirs exceeds 0.04×10−3 μm2, substantial filtration of CO2 into the reservoir matrix occurs near the well bore, limiting the activation of natural fractures around the fracture tip. A higher proportion of CO2 preenergizing during fracturing is conducive to improve the fracture complexity while reducing the fracture aperture.
Performance Analysis of Machine Learning Algorithms for Cardiovascular Diseases Detection.
Authors: Okemiri Henry Anayo , Alo Rita U. , Nnamene Christopher C.
Published: March 2023

Machine learning and the internet of things are rapidly gaining popularity around the world, particularly in the healthcare area. Heart disease is one of the deadliest diseases, and early detection is critical for many medical professionals in order to save their patients' lives. The research's key contributions are a comparative comparison of various machine learning models for identifying heart disease with higher accuracy than existing methods. Three models have been introduced for this purpose: Naive Bayes (NB), Random Forest (RF), and Support Vector Machine (SVM). For a more exact evaluation, their performances were evaluated and compared using several criteria. The RF is the best ideal model for prediction, according to the comparison research, since it has a higher prediction potential than other models, with a 100% accuracy on various cardiac illnesses. The dataset came from the University of California, Irvine's heart disease repository (UCI).
Localization and Priority-Based Multi-objective QoS Congestion Control Routing for Underwater Wireless Sensor Network
Authors: S Sandhiyaa , Gomathy C
Published: March 2023

The nodes in the sensor network have a wide range of uses, particularly on under-sea links that are skilled for detecting, handling as well as management. The underwater wireless sensor networks supports collecting pollution data, mine survey, oceanographic information collection, aided navigation, strategic surveillance, and collection of ocean samples using detectors that are submerged in water. Localization, congestion routing, and prioritizing traffic is the major issue in an underwater sensor network. Our scheme differentiates the different types of traffic and gives every type of traffic its requirements which is considered regarding network resources. Minimization of localization error using the proposed angle-based forwarding scheme is explained in this paper. We choose the shortest path to the destination using the fitness function which is calculated based on fault ratio, dispatching of packets, power, and distance between the nodes. This work contemplates congestion conscious forwarding using hard stage and soft stage scheme which reduce the congestion by monitoring the status of the energy and buffer of the nodes and controlling the traffic. The study with the use of the ns3 simulator demonstrated that a given algorithm accomplishes superior performance for loss of packet delay of latency and power utilization than the existing algorithms.
Data Mining Method in Seismology by Applying Cellular Automaton Equivalence of Ground Vibration Fluctuations Recorded Near the Epicenter of the 2011 Mw 9 East Japan Earthquake
Authors: Kikuchi Hiroyuki
Published: March 2023

The data mining method is proposed to discover the target physical phenomena in the ground vibration velocity fluctuation (GVF) recorded near an epicenter of the Great East Japan Earthquake of magnitude 9 (GEJE). Although the GVF can be discussed in the framework of the master equation which represents the thermodynamics of a stochastically fluctuating non-equilibrium system, the relation between the thermodynamic parameters and seismology-related phenomena is hardly known. So, we introduce cellular automata (CA) to analogically interpret the physical phenomena of interest as thermodynamic parameters, and show the thermodynamic equivalence between GVF and CA. These CA-derived thermodynamic parameters are then expected to deliver physical phenomena similar to those of the target when evaluated on the GVF data. Since the physical phenomena obtained by the data mining are analogous phenomena, we verify the physical consistency between the target physical phenomena and analogous physical phenomena at the end of the data mining. In the demonstrated example of data mining, the stress relaxation signal immediately after GEJE is discovered from the recorded GVF data by deriving the thermodynamic parameters representing the stress relaxation of CA and evaluating these thermodynamic parameters for the recorded GVF data. Furthermore, the elastic rigidity and viscosity of the underground structures are estimated from the stress relaxation signal. The non-traditional features of this study are that the GVF of interest is a weak fluctuation signal with no specific waveform and that the key role of CA is to analogically interpret physical phenomena as thermodynamic parameters.
Accuracy of a noninvasive estimated continuous cardiac output measurement under different respiratory conditions: A prospective observational study
Authors: Takakura Masashi , Fujii Tasuku , Taniguchi Tomoya , Suzuki Shogo , Nishiwaki Kimitoshi
Published: March 2023

Purpose
Recently, the estimated continuous cardiac output (esCCO) system was developed as a noninvasive hemodynamic monitoring alternative to the thermodilution cardiac output (TDCO). However, the accuracy of continuous cardiac output measurements by the esCCO system compared with TDCO under different respiratory conditions remains unclear. This prospective study aimed to assess the clinical accuracy of the esCCO system by continuously measuring the esCCO and TDCO.
Methods
Forty patients who had undergone cardiac surgery with a pulmonary artery catheter were enrolled. We compared the esCCO with TDCO from mechanical ventilation to spontaneous respiration through extubation. Patients undergoing cardiac pacing during esCCO measurement, those receiving treatment with an intra-aortic balloon pump, and those with measurement errors or missing data were excluded. In total, 23 patients were included. Agreement between the esCCO and TDCO measurements was evaluated using Bland–Altman analysis with a 20-minute moving average of the esCCO.
Results
The paired esCCO and TDCO measurements (939 points before extubation and 1112 points after extubation) were compared. The respective bias and standard deviation (SD) values were 0.13 L/min and 0.60 L/min before extubation and −0.48 L/min and 0.78 L/min after extubation. There was a significant difference in bias before and after extubation (P<0.001); the SD before and after extubation was not significant (P=0.315). The percentage errors were 25.1% before extubation and 29.6% after extubation, which is the criterion for acceptance of a new technique.
Conclusion
The accuracy of esCCO system is clinically acceptable to that of TDCO under mechanical ventilation and spontaneous respiration.
Temozolomide Combined with Radiotherapy Can Benefit Patients with Glioma: A Systematic Review and Meta-Analysis
Authors: huang Qinhong , Yang Lihui , Ye Zhenwei , Ke Yiquan , Yang Jing
Published: March 2023

Background: Glioma originates from glial cells of the nervous system and is the most common malignant tumor in the brain. Temozolomide is considered as a promising medicine that can improve the overall survival (OS) and progress-free survival (PFS) rate of patients with glioma after operation. However, whether radiotherapy plus temozolomide has substantive role for glioma patients remains controversial.
Methods:We conducted a meta-analysis included 10 Randomized controlled trials (RCTs) encompassing 2703 patients to evaluate the efficacy and safety of radiotherapy plus temozolomide for glioma. EMbase, PubMed, Web of Science, and Cochrane library were searched. Our study strictly follows the PRISMA guideline.
Results:Overall, compared with receiving radiotherapy alone, patients through radiotherapy combined with temozolomide has substantial benefit on both OS (HR=0.78; 95% CI: 0.62-0.98; P =0.03) and PFS (HR=0.62; 95% CI: 0.49-0.78; P <0.0001). The best effect shows in patients receiving radiotherapy combined with both concurrent and adjuvant temozolomide on both OS (HR=0.66; 95% CI: 0.58-0.74; P <0.00001) and PFS (HR=0.55; 95% CI: 0.48-0.62; P <0.00001), when compared with radiotherapy alone. Whereas, temozolomide monotherapy do not show greater benefits than radiotherapy alone on OS (HR=0.93; 95% CI: 0.74-1.14; P =0.53). Moreover, radiotherapy plus temozolomide obviously increase the incidence of hematological complications than only radiotherapy (RR=10.31; 95% CI: 4.49-23.71; P<0.00001). Also, our meta-analysis suggested that MGMT methylation test can be helpful for evaluating prognosis, determining individualized treatment and forecasting the curative effect.
Conclusion:Radiotherapy combined with temozolomide, especially combined with both concurrent and adjuvant temozolomide has great benefit on both OS and PFS of glioma patients. Conditionally, patients with glioma receiving glioma MGMT methylation test have advantage over evaluating prognosis, determining individualized treatment and forecasting the curative effect. Last but not least, monitoring blood routine and remedying the possible abnormalities in time is especially necessary of patient receiving temozolomide therapy.
PAI-1 regulates AT2-mediated re-alveolarization and ion permeability
Authors: Ali Gibran , Zhang Mo , Chang Jianjun , Zhao Runzhen , Jin Yang , Ji Hong-Long
Published: March 2023

Background Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung epithelium has not been understood completely. This study aimed to investigate the role of Serpine1 in the regulation of alveolar type 2 epithelial cell (AT2) fate in a humanized mouse line carrying diseased mutants (Serpine1Tg).
Methods Wild type (wt) and Serpine1Tg AT2 cells were either cultured as monolayers or 3D alveolospheres. Colony forming assay and total surface area of organoids were analyzed. AT1 and AT2 cells in organoids were counted by immunohistochemistry and fluorescence-activated cell sorting (FACS). To test the potential effects of elevated PAI-1 on the permeability in the epithelial monolayers, we digitized the biophysical properties of polarized AT2 monolayers grown at the air-liquid interface.
Results A significant reduction in total AT2 cells harvested in Serpine1Tg mice was observed compared with wt controls. AT2 cells harvested from Serpine1Tg mice reduced significantly over the wt controls. Spheroids formed by Serpine1Tg AT2 cells were lesser than wt control. Similarly, the corresponding surface area, a readout of realveolarization of injured epithelium, was markedly reduced in Serpine1Tg organoids. FACS analysis revealed a significant suppression in the number of AT2 cells, in particular, the CD44+ subpopulation, in Serpine1Tg organoids. A lesser ratio of AT1:AT2 cells in Serpine1Tg organoids was observed compared with wt cultures. There was a significant increase in transepithelial resistance but not amiloride inhibition.
Conclusions Our study suggests elevated PAI-1 in injured lungs downregulates alveolar epithelial regeneration by reducing the AT2 self-renewal, particularly in the CD44+ cells.
Effects of Observational Uncertainty and Models Similarity on Climate Change Projections
Authors: Pathak Raju , Prasad Dasari Hari , Karumuri Ashok , Hoteit Ibrahim
Published: March 2023

Climate change projections (CCPs) are based on the multimodel means of individual climate model simulations that are assumed to be independent. However, model similarity leads to projections biased toward the largest set of similar models and the underestimation of uncertainties. We assessed the influence of similarities in CMIP6 through CMIP3 CCPs. We ascertained model similarity due to shared physics/dynamics and initial conditions by comparing simulated spatial temperature and precipitation with the corresponding observed patterns and accounting for inter-model spread relative to the spread across observational datasets. After accounting for similarity, the information from 57 CMIP6, 47 CMIP5, and 24 CMIP3 models could be explained by just 11 effective models, without significant differences in globally averaged climate change statistics. The effective models showed a smaller globally averaged temperature rise of 0.25ºC (~0.5ºC–1ºC in some regions) by the end of 21 century relative to the multimodel mean of all models for socioeconomic pathways 5–8.5.
Patterns of Treatment Response Profile in Sri Lankan Traditional Medicines on Chronic Kidney Disease of Unknown Etiology Patients in North Central region, Sri Lanka: A Follow-up Study
Authors: Suresh Sugandhika , Fernando Sanuri , Galgamuwa Lahiru Sandaruwan , Kumarasinghe Nishantha , Perera Kamal , Suriyakumara Vindika , Aslam Fahim , Hakmanage Navodi Mekala , Lankeshwari Aloka , Madushani Rangika , Karunarathne Chaminda , Udara Supun
Published: March 2023

Background: Since early nineties investigators in Sri Lanka have noticed an alarmingly high incidence of a new form of chronic kidney disease of uncertain etiology (CKDu) in North Central Region of the country. The purpose of the present study was to assess the treatment response profile of a selected traditional medicine used for Chronic Kidney Disease of unknown etiology in Sri Lanka.
Methods: A follow-up study was performed with Chronic Kidney Disease of unknown patients receiving a selected traditionalmedicine in Sri Lanka. Socio-demographic characteristics and anthropometric measurements were documented. Blood and urine samples were collected for biochemical analysis. Multistate Markov model was used to estimate rates of transition between stages of chronic diseases.
Results: Anthropometric and biochemical parameters of 96 CKDu patients and 20 normal individuals were recorded in a period of six months. Serum creatinine, urine micro albumin, Albumin creatinine ratio and Systolic Blood pressure values were significantly decreased in the six-month study period. eGFR value was significantly increased over the six-month study period. Positive correlations were identified between ACR-Micro albumin, ACR-BMI and ACR-eGFR while e-GFR-serum creatinine, e-GFR-micro albumin and ACR-serum creatinine showed negative correlations.
Conclusions: A significant improvement in both biochemical and anthropometric parameters were observed among patients who underwent Sri Lankan traditional medicine treatment. Continuous follow up programs are important to improve biochemical and physical parameters as well as their quality of life.
Vacuum Expansion and Collapse Inside an Infinite Shell
Authors: Laforet Christopher
Published: March 2023

The FRW model of cosmology assumes a Universe with uniform pressure and density everywhere in space at a given time. But at the largest scales, the Universe has a web-like structure surrounding large voids, violating these assumptions. Furthermore, a given region of spacetime is describable only by a single metric and therefore it cannot be that the Universe is modelled as an FRW perfect fluid since this would be the incorrect description of both the web and the voids. The cosmic web must be described by metrics with non-zero energy-momentum tensors with non-uniform pressure and density describing the matter within it. Therefore, the model of cosmology describing the expansion of the Universe must be a vacuum solution describing the empty spaces in the Universe surrounded by an infinite, massive shell (the surrounding Universe). Taking the expanding balloon analogy of the expansion of the Universe, the matter-dense portions of the Universe would be like knots in the balloon which stay knotted while the vacuum between them expands. The internal Schwarzschild metric is that model. The source of the Schwarzschild metric is shown to be at the event horizon, a location/time of infinite density, not at the singularity, as it is currently assumed. The spatial homogeneity of the metric is demonstrated by visualizing the geometry in the extrinsic "Kruskal-Szekeres" coordinates (visualized in 1+2 dimensions). Using the coordinate age of the Universe and transition redshift, this predicts the accelerated expansion, the Hubble diagram fits currently available cosmological data, and it gives a Hubble constant H0 of 71.6km/s/Mpc. The angular term of the metric describes the relativistic kinematic precession effect known as Thomas Precession which can be interpreted as spin about the time dimension.
How Australian environmental non-governmental organisations frame and enact climate justice
Authors: Gulliver Robyn , Vachette Astrid , Boddington Sarah
Published: March 2023

This paper seeks to examine how Australian environmental non-governmental organisations (ENGOs) communicate about and mobilise their supporters for climate justice. ENGOs play an important role in raising awareness and changing values, attitudes and behaviours related to climate justice. However, while a number of Australian ENGOs have begun incorporating language around climate justice in their communications, it remains unclear how they are conceptualised and enacted. Using data collected from 619 ENGO websites and 149 grant applications, we examine how ENGOs describe climate justice and the collective action frames they use to mobilise action. We found that while few ENGOs provided detailed explanations of climate justice on their websites, they primarily frame climate injustice as a procedural and distributive problem. The fossil fuel sector was most commonly identified as the cause of climate injustice, and First Nations communities most commonly affected. ENGOS consistently linked specific climate justice dimensions to relevant issues and solutions, suggesting a sophisticated understanding of how climate justice can be enacted. However, they primarily proposed incremental tactics involving education, solidarity and allyship behaviours, rather than radical actions through which to drive a transformative agenda of social, political or economic change. We conclude the paper with a discussion of applied implications for ENGOs and suggestions for future research.
Social media and mental health in students: a cross-sectional study during the covid-19 pandemic
Authors: Nazari Abouzar , Hossennia Maedeh , Garmaroudi Gholamreza , Torkian Samaneh
Published: March 2023

Background:
Social media causes increased use and problems due to their attractions. Hence, it can affect mental health, especially in students. The present study was conducted with the aim of determining the relationship between the use of social media and the mental health of students.
Materials and methods:
The current cross-sectional study was conducted in 2021 on 781 university students in Lorestan province, who were selected by the Convenience Sampling method. The data was collected using a questionnaire on demographic characteristics, social media, problematic use of social media, and mental health (DASS-21). Data were analyzed in SPSS-26 software.
Results:
Shows that marital status, major, and household income are significantly associated with lower DASS21 scores (a lower DASS21 score means better mental health status). Also, problematic use of social media (β = 3.54, 95% CI: (3.23, 3.85)) was significantly associated with higher mental health scores (a higher DASS21 score means worse mental health status). Income and social media use (β = 1.02, 95% CI: 0.78, 1.25) were significantly associated with higher DASS21 scores (a higher DASS21 score means worse mental health status). Major was significantly associated with lower DASS21 scores (a lower DASS21 score means better mental health status).
Conclusion:
This study provides further evidence of the association between problematic social media use and poor mental health among college students and supports future research to focus on the underlying mechanisms of problematic use of social media.
M6A Methylation Modification–Mediated Mucosal Immune Microenvironment in Crohn's Disease
Authors: Lan Shui-Qing , Huang GuiLiu , Huang ZanSong
Published: March 2023

Objective
To explore the pathogenesis of Crohn's disease by revealing the relationship between m6A methylation and Crohn's disease
Methods
The GEO (GENE EXPRESSION OMNIBUS) database was used to download the dataset GSE186582 on Crohn's disease, including standard tissue samples and Crohn's disease tissue samples, and the Expression of M6A-related genes in the calibrated dataset was obtained. Through the observation and comparison of the random forest tree method and machine learning method, it was determined that the random forest tree model could be used to screen the characteristic genes of diseases. Samples were divided into subtypes by the expression of m6A-related genes, and the relationship between different types and immune cells was analyzed and verified by principal component analysis. The expression of M6A-related genes and the relationship between the genotyped samples and immune cells were analyzed. We classified Crohn's disease according to the expression of differential genes, finally established the corresponding relationship between different types by Sankey diagram and analyzed the expression of Crohn's disease-related disease genes in two different types.
Results
By comparing the model construction methods, we found that the residual value of the random forest tree model method was low, and the area under the ROC curve was 1. Therefore, we chose the random forest tree method to construct the model and screen characteristic genes and found 11 methylation-related genes related to m6A in Crohn's disease, such as RBM15, YTHDF3 and RBM15B. According to the expression of 11 M6A-related genes, the samples were divided into two subtypes: activated B cells, immune B cells and MDSC (myeloid-derived inhibitory cells) expressed more than the B subtype (P value is less than 0). There was a significant positive correlation between the METTL3 gene, M6A recognition enzyme HNRNPA2B and activated CD4 + T cells. The expressions of activated B cells, MDSC and immune B cells in genotype B were significantly higher than those in genotype A (P < 0.05).
Conclusion
m6A modulators play an essential role in Crohn's disease, and the study of their patterns can guide future immunotherapy strategies for Crohn's disease