bluuebunny/crossref_metadata_2025 huggingface dataset:
Adventitious Bud Differentiation and Development in Leaf Cuttings of Dionaea muscipula Ellis Ex. L. (Venus Fly-trap) Cultured in Vitro1
Authors: Parliman Bruce J. , Evans Phillip T. , Mazur Anthony R.
Published: July 2022

Excised whole leaves of in vitro cultured Venus fly-trap plants produced up to 15 adventitious bud- (AB) and lateral bud-derived (LB) plantlets in 60 to 90 days, when cultured on a modified Murashige and Skoog salt medium supplemented with naphthaleneacetic acid (NAA) at 1.9 mg/liter and 6(-γ,γ-dimethylallylamino)-purine (2iP) at 0.2 mg/liter and grown under a 16 hr photoperiod at 22°C. Leaves dipped for 10 seconds to 24 hr in various concentrations of 6-benzylamino purine (BA), 2iP, NAA and indolibutyric acid (IBA) improved the production of plantlets over undipped leaves. A 24 hr 2iP dip at 2.1 mg/liter produced the largest average number of adventitious and lateral bud-dervied plantlets. Lateral bud-derived plantlets are proposed to have arisen from nodes within the rhizomes of previously derived plantlets. Morphologically, the resulting chain-like growth habit of lateral bud-derived plantlets is very unusual and provides an increased number of plantlets for subcultures.
Galactose Concentration and Metabolism in Pericarp Tissue from Normal and Non-ripening Tomato Fruit1
Authors: Gross Kenneth C. , Saltveit Mikal E.
Published: July 2022

Free galactose was detected in outer pericarp tissue from fruit of ‘Heinz 1350’ and nor tomato (Lycopersicon esculentum Mill.). The amount of free galactose increased almost 8-fold in ‘Heinz 1350’ fruit during ripening. In contrast, it did not change significantly in 32- to 52-day-old (post-pollination) nor fruit. A 25 μl drop of water ± 100 μg galactose was applied to the locular surface of 1.5 cm diameter pericarp disks. While disks from 40- and 60-day-old nor tomatoes, and from mature green and pink ‘Heinz 1350’ tomatoes, were able to reduce the level of free galactose to levels found in control tissue within 48 hr, disks of red ripe tissue were only able to metabolize 45% of the added galactose within this time. Pink ‘Heinz 1350’ tomatoe disks lost galactose more slowly than disks of mature green tomatoes. The results suggest that the increased amount of free galactose in pericarp tissue of ripening tomatoes may be the result of their progressive inability to metabolize galactose as they ripen.
Salinity Effects on Rice after the Boot Stage1
Authors: Kaddah M. T. , Lehman W. F. , Meek B. D. , Robinson F. E.
Published: July 2022

Effect of salinity on rice (Oryza sativa L.) after the boot stage has been controversial in the literature. Some authors maintain that rice is sensitive to salt at flowering, whereas others have found no evidence to support these views. The present greenhouse study evaluates the interaction after the boot stage of salinity, soil texture, and rate of drainage on rice development. Breeding line IV 213 was transplanted into 11‐liter pots filled with either silty clay or silt loam soil and irrigated with Colorado river water, S1 (EC = 1.4 mmho/cm), until after the boot stage. Then pots were irrigated until harvest with S1, S2 (EC = 4.0 mmho/cm), and S3 (EC = 8.0 mmho/cm) under the following three drainage rates from the bottom of the pots: 0, D0; 100, D1; and 200 ml/day, D2. The pots soils were always submerged and treatment water was added to replenish water lost by ET and internal draining.

Soil and plant analyses showed that:

Average salinities in the root zone were 2 to 4 times the salinities of the respective irrigation waters. In general, salinities increased with plant development and with decreasing rate of drainage. Salt components added to Colorado river water increased in both straw and grain without effect on yield.

Mature grain yield of S1 and S2 did not differ significantly; average grain yield of S3 was 84% of S1 More reduction in yield would be expected if rice was sensitive to salt after the boot stage.

Average grain yield on silty clay soil was 16% higher than on silt loam soil.

Neither straw yield nor ratio of aborted to mature grain differed significantly among the various treatments. Also rate of drainage had no appreciable effect on concentration of soluble Fe, Mn, or dissolved O2 in the soil solution. The unexpected effect of rate of drainage was probably due to frequent replenishment with fresh irrigation water.
Seed Priming Does Not Improve Corn Yield in a Humid Temperate Environment
Authors: Subedi K. D. , Ma B. L.
Published: July 2022

Early emergence and stand establishment of corn (Zea mays L.) is considered to be one of the most important yield‐contributing factors in eastern Ontario. A pot experiment and two field experiments were conducted in Ottawa, Canada, to evaluate the effects of seed priming with water, osmotic solution (2.5% KCl), and plant growth regulators (indole acetic acid, cytokinin, ethephon and gibberellic acid) on emergence, seedling vigor, N response, and grain yield of corn. Time to seedling emergence, seedling vigor, and growth were measured in a pot experiment under a greenhouse condition while field performances, N response, and grain yield were determined in field experiments. In the greenhouse study, none of the treatments were better than the unsoaked control. Under field conditions, both hybrids and N application had significant effects on grain yield, but there was no yield advantage due to any of the seed treatments. Seed soaking with 20 ppm gibberallic acid (GA3) solution for 30 min improved seedling vigor (i.e., seedling height and growth), but this was not translated into greater grain yield. Seed soaking with water for 16 h significantly reduced percentage emergence and final plant stand in 2002 while in 2003, seed soaking with 2.5% KCl and 20 ppm GA3 solution for 16 h significantly reduced plant stand and grain yield under the 150 kg N ha−1 treatment. Despite some positive effects of seed priming on seedling vigor and stand establishment, none of the seed‐priming treatments tested showed beneficial effects on grain yield and N efficiency under the temperate‐humid conditions such as in eastern Ontario.
Nitrogen Management for Mid‐Atlantic Hard Red Winter Wheat Production
Authors: Kratochvil Robert J. , Harrison Michael R. , Pearce Justin T. , Conover Kevin J. , Sultenfuss Mark
Published: July 2022

Although soft red winter wheat (SRWW) (Triticum aestivum L.) is the predominant class in the Mid‐Atlantic, there is a recently established program for producers to grow hard red winter wheat (HRWW). This program offers a base price plus premiums for HRWW meeting quality (test weight and protein content) standards. This study's objectives were to evaluate the effect of N management strategies on HRWW yield and protein content and to determine the economic return using those strategies. Two HRWW cultivars used by producers in this HRWW program were produced at two locations in Maryland in a split plot arrangement of N treatments within a randomized complete block experimental design. Main plots (2002) were a factorial arrangement of those cultivars and four fall and Feekes growth stage (GS) 2/3 N treatments. Split plots (2002) were eight N timing and rate combinations at GS 5/6, GS 8, and/or GS 10.1. Main plots (2003) were a factorial arrangement of the cultivars and fall N supplied by either ammonium sulfate (AS) or urea‐ammonium nitrate (UAN) and GS 2/3 N treatments. Split plots (2003) were GS 5/6, GS 8, and 10.1 N timing and rate combinations. Wheat yield was significantly improved with GS 8 and/or 10.1 N applications both years. Protein content responded to GS 8 and 10.1 N applications in 2002; however, the response in 2003 was dependent on location and N amount at GS 5/6. Within the price and premium structure, best return was observed for split applications of N; 50 or 68 kg ha−1 at GS 2/3 followed at GS 5/6 with 50 or 68 kg N ha−1. No fall N benefit was observed.
Comments on “AVAIL Phosphorus Fertilizer Enhancer: Meta‐Analysis of 503 Field Evaluations” by B.G. Hopkins et al. Agron. J. 110:389–398 (2018)
Authors: Chien S.H. , Rehm G.W. , Grove J.H. , Edmeades D. , McBride R. , Hopkins Bryan G. , Fernelius Kaitlynn J. , Hansen Neil C. , Eggett Dennis L.
Published: July 2022

Core Ideas

Fixation of fertilizer phosphorus in soils often decreases phosphorus efficiency.

Avail has been reported to enhance fertilizer phosphorus efficiency.

A review on the effect of Avail on soil phosphorus‐fixation is critically discussed.
Applying Community of Inquiry for Language Learning Among English Preservice Teachers
Authors: Yudhiantara Rully Agung
Published: July 2022

Community of Inquiry allows learning activities to run optimally. There are three components in CoI: teaching presence, social presence and cognitive presence. This study aims to investigate the implementation of CoI among English Language Education students in lectures, their opinions, the components of teaching presence, cognitive presence and social presence that arise. The method used in this research is qualitative. Data were collected through observation, Focus Group Discussion and Content Analysis. The results of the study show that CoI can be implemented for lecture activities among English Education students. They argue that CoI provides many benefits for their lecture activities. The components of teaching presence, social presence and cognitive presence appear in learning activities during the implementation of CoI.
TO EVALUATE THE OUTCOME OF ELASTIC NAILING ALONG WITH EXTERNAL FIXATOR IN OPEN TIBIA FRACTURES
Authors: Pandey K.K , Naik Sparsh , Vidyarthi Ashok
Published: July 2022

Background: Open tibial fractures account for over 40% of all open fractures and are frequently accompanied by significant damage to soft tissues, including skin, muscle, and neurovascular structures . This article presents a intramedullary(TENS)- and external fixator technique. The purpose of this study is TO EVALUATE THE OUTCOME OF ELASTIC NAILING ALONG WITH EXTERNAL FIXATOR IN OPEN TIBIA FRACTURES . Materials and Methods: Following ethical approval, thirty patients with tibial fractures were treated by the EF-TENs system between NOVEMBER 2019 and SEPTEMBER 2021. The follow-up studies included clinical and radiographic examinations. All relevant outcomes were recorded during follow-up. Results: All 30 patients were assessed by follow-ups. According to the Anderson-Gustilo classification, there were 19 Type Grade II, 6 Type Grade IIIA and 5 Type Grade IIIB. All thirty patients were achieved follow-ups. All follow-up fractures united at last, but delayed union was observed in 5/30 patients. The average union time is 23.83+_4.47 weeks (range, 18â€“32 weeks). The main complication mentioned in this study was pin track infection, which occupied 6/30 cases. According to Johnerâ€“Wruhscriteriaof tibial shaft fractures, 19 fractures had excellent, 5 had good, 5 had fair and 1 had poor results. Conclusion: This study indicated that the outcome of elastic nailing along with external fixator , as a definitive intra- and extramedullary fixation technique, which was effective in treatment of open tibial fractures.
DETERMINANTS OF COMPETITIVE ADVANTAGE OF CONVECTION SMES TOWARDS DIGITAL TRANSFORMATION (CASE STUDY IN WEST JAVA PROVINCE)
Authors:   University of Pancasila, Indonesia., Suryana AgusIim , Purwoko Bambang ,   University of Pancasila, Indonesia., a Zulkifly ,   University of Pancasila, Indonesia.
Published: July 2022

This study aims to develop competitive advantage in order toimprove competitivenessandmaintainitscompetitivepositionagainst competitors,bothwithimportedanddomesticproducts.Theresearch examinesandanalyzestheinfluenceoforganizationalculture,business environment,innovation,rawmaterialrequirements,ondigital transformationandcompetitiveadvantage.Digitaltransformationis notonlyadependentvariableonfourindependentvariables,butalso anindependent variablewhentestingandanalyzingitseffecton competitiveadvantage. ThesampleinthisstudyweretheownersofconvectionSMEsinWest Java.Todetermine the effectbetweenvariables,the analysisusedistheStructuralEquationModel(SEM)with the Partial LeastSquare (PLS)approach.Theresearchconcludesthatorganizationalcultureand innovationhavenosignificant effecton digital transformation.The businessenvironmentandtheneedforrawmaterialshaveasignificant effect ondigitaltransformation. Organizational culture,innovation, andtheneedforrawmaterialshaveasignificanteffectoncompetitive advantage.Inthebusinessenvironment,digitaltransformationhasno effect on competitiveadvantage.
UNUSUAL PRESENTATION- MY BRAIN IS WET WITHOUT ALCOHOL: A CASE REPORT OF NON ALCOHOLIC WERNICKES ENCEPHALOPATHY
Authors:   Emergency Medicine Department, Apollo Hospitals International Limited, Plot 1A, GIDC Estate, Bhat, Gandhinagar - 382428., Sharma Abhishek , N. Panchal Smiti ,   Emergency Medicine Department, Apollo Hospitals International Limited, Plot 1A, GIDC Estate, Bhat, Gandhinagar - 382428., Thakkar Vidhi ,   Emergency Medicine Department, Apollo Hospitals International Limited, Plot 1A, GIDC Estate, Bhat, Gandhinagar - 382428.
Published: July 2022

Case of 72 years male with Nonalcoholic Wernickes encephalopathy (NWE) who was initially investigated managed as Stroke, Metabolic encephalopathy or Suspected Meningoencephalitis. Patient managed clinically, until MRI report and with clinical correlation patient was diagnosed with NWE. Thiamine deficiency is associated with chronic alcoholics which was not among the common differentials in this case and its emphasis in ED among the differentials to be ruled out. A male who is Non-alcoholic was brought to ED having Slurred Speech, confusion, weak memory and evaluated, investigated with multiple tests which turned out to be normal Until MRI showed a well defined area of hyper intensity on DWI in peri-ductal region possibility of WE. We recommend using criteria to diagnose and treat NWE as early as possible to avoid misdiagnosis and treatment delays. We should focus on patients with altered mental symptoms even in coma, administering parenteral thiamine.
EWINGS SARCOMA - A CASE REPORT
Authors:   MBBS,MS,MCh,FIACS Assistant Professor Cardiothoracic Surgery, Pmch, Patna, Bihar., Verma Amitabh
Published: July 2022

Ewings sarcoma usually arises in the bones of children and adolescents. I herein report a 10-year-old boy with Ewings Sarcoma in the second rib of right chest. The diagnosis was confirmed by histo- pathological studies, and several imaging studies. He was suffering from this problem since 6 months. Thoracotomy was done under general anesthesia. Cricket ball size tumour was excised and sent for histopathology. The biopsy report confirmed Ewings Sarcoma. The patient was discharged after 3 weeks of treatment.
THE APPLICATION OF STEM-CP-BASED SOUND WAVE MODULE TO IMPROVE STUDENTS CRITICAL THINKING SKILLS AND INDEPENDENT LEARNING
Authors:   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., Aldilah Rosyadi Fani , a Sutarto ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., Prihatin Jekti ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., b Indrawati ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121.
Published: July 2022

Competition in science and technology inthe 21st-century created challenges in the field of education that triggered the development of scientific approaches. One of them was the STEM-CP approach which consisted of Science, Technology, Engineering, Mathematics and Contextual Problems. One of the advantages of the STEM-CP approach was that it could train students critical thinking skills. The STEM-CP approach could be applied in learning media, one of which was a module that was useful for training students learning independence. The purpose of this study was to describe the application of the STEM-CP-based sound wave module to the critical thinking skills and learning independence of high school students in physics. The research design used was one group pretest-posttest. As the results of the study, students experienced an increase in students critical thinking skills with an N-gain value between 0.67 to 0.74 in the medium and high categories. The fairly good category changed to 85 in the impressive category. So that the application of the STEM-CP-based sound wave module was proven to be successful in improving students critical thinking skills and independent learning.
The impact of mobile banking use on the Islamic financial institutional interest: A study in Indonesia
Authors: Alam Azhar , Hendratmi Achsania , Santika Wati Mega , Hakim Lukmanul
Published: July 2022

M-banking is one of the services that Islamic banking provides to its users. With M-banking, customers can more easily obtain information without queueing at the bank. This study investigates the impact of Islamic mobile banking on customers’ interests. To explore the phenomenological impact, this study used a qualitative approach by applying in-depth interviews with 15 Islamic M-banking users from various backgrounds. This study analyzed the data by data reduction, display, and conclusion. The conclusion of this study revealed some positive and negative effects on the users. The positive effect is that it saves time, especially for students and workers who are busy with their daily activities. The available features and facilities such are credit purchases and online Islamic social payments ease them in saving time. However, there are also negative consequences for users. Some customers are susceptible to data theft by irresponsible people and face difficulties in using sophisticated mobile phones that not all customers have. Inconvenience telephone and text messages on behalf of a bank insulted users of Islamic M-banking and reduced their comfort. This study recommends that Islamic banks improve the data security system to ensure customer convenience when using M-banking.
Paradigma de dupla tarefa no contexto de quedas de idosos: uma revisão integrativa
Authors: Nascimento Marcelo de Maio
Published: July 2022

Com o envelhecimento, o desempenho cognitivo, a marcha e o equilíbrio são afetados. Diante disso, idosos apresentam dificuldade para executar simultaneamente duas ou mais tarefas em situações cotidianas da vida. Objetivo: Sumarizar estudos que investigaram a relação entre marcha, equilíbrio e quedas de idosos utilizando o paradigma de dupla tarefa. Metodologia: Revisão integrativa da literatura que incluiu estudos publicados entre os anos os anos de 2008 e 2021, realizada nas bases eletrônicas de dados PubMed, CINAHL e Web of Science com os descritores MeSH: marcha OU caminhada OU equilíbrio OU postura OU idade (60 anos ou mais) OU quedas OU quedas acidentais OU dupla tarefa OU dupla tarefa OU paradigma de dupla tarefa OU tarefa cognitiva. Resultados: 1.280 estudos foram encontrados e 34 selecionados. Verificou-se que o paradigma de dupla tarefa é uma estratégia útilà identificação prévia de idosos caidores, além de que exercícios de dupla tarefa podem beneficiar o desempenho da marcha e do equilíbrio, reduzindo o risco de quedas. Conclusão: Paradigmas de dupla tarefa são medidas eficazes à identificação de distúrbios da marcha e do equilíbrio. No contexto de queda de idosos, o emprego dessa metodologia apresenta vantagens em relação aos exercícios fundamentados na tarefa única. Estudos futuros devem buscar homogeneidade entre as medidas de avaliação e buscar um melhor detalhamento dos exercícios empregados.
Fulfillment of the obligation to protect the Matherland, independence and territorial integrity of Ukraine as a circumstance that excludes criminal wrongfulness of the act
Authors: Sharmar Olha Mykhailivna
Published: July 2022

The article is devoted to the analysis of legislative changes related to the criminal law regulation of relations arising in connection with the imposition of martial law on the territory of Ukraine as a result of the armed aggression of the Russian Federation on February 24, 2022. Legislative provisions on ensuring the participation of civilians in the defense of Ukraine are analyzed. The content of the circumstance that excludes the criminal illegality of the act of fulfillment of the duty to protect the Matherland, independence and territorial integrity of Ukraine, provided for in Article 431 of the Criminal Code of Ukraine. The concept of combat immunity and its relationship with the circumstance that excludes the criminal illegality of the act - the act associated with risk. Combat immunity is the release from military responsibility of military command, servicemen, volunteers of the Territorial Defense Forces of the Armed Forces of Ukraine, law enforcement officers who, in accordance with their powers, participate in the defense of Ukraine, persons defined by the Law of Ukraine , including criminal, for the loss of personnel, military equipment or other military property, the consequences of the use of armed and other force in repelling armed aggression against Ukraine or the elimination (neutralization) of armed conflict, other defense tasks of Ukraine using any types of weapons (weapons), the occurrence of which with reasonable care could not be foreseen in the planning and implementation of such actions (tasks) or covered by justified risk, except in cases of violation of laws and customs of war or use of force under international treaties, viscosity of which is provided by the Verkhovna Rada of Ukraine". It is argued that the use of the phrase "impossible to predict" in the concept of combat immunity means the absence of negligent guilt and the composition of the criminal offense. Legislative inconsistencies between the provisions of the Criminal Code of Ukraine and the Law of Ukraine "On Defense", the Law of Ukraine "On the National Police" on non-prosecution for repelling the enemy in the face of armed aggression of the Russian Federation are analyzed.
GEOPOLITICAL ROLE OF UKRAINE
Authors: Polishchuk Ihor
Published: July 2022

The article considers the geopolitical positioning of Ukraine under the conditions of formation of a multipolar model of the world order. The main factors influencing the place and role of Ukraine on the modern geopolitical map of the world are revealed. The territory of Ukraine has always been at the center of geopolitical events. Ukraine at the beginning XXI century is on the latitudinal geopolitical axis, the poles of which are the European Union and the Russian Federation. It is concluded that the effective geopolitical positioning of Ukraine at the present stage is the eastern outpost of Western democratic civilization, which resists the authoritarian threat from the East to the entire collective West. Ukraine's European choice requires concretization and clear definition of the terms of accession to the EU as a full member. Otherwise, it is necessary to revise the geostrategic doctrine towards greater sovereignty within the framework of Euro-Atlantic civilization.
Field scale variability in soil properties and silage corn yield
Authors: BİROL Murat , GÜNAL Hikmet
Published: July 2022

Field scale spatial variability of soil properties, crop quality parameters and yield are needed to evaluate the efficiency of management practices in crop production. The purpose of this study was to determine the magnitude of field variability in soil properties, silage yield of corn (Zea mays L.) varieties, and to characterize their spatial structures, and map the stated attributes. The experiment was conducted in an alluvial flood plain of lower Kazova watershed in Tokat province of Turkey. Several physical and chemical soil properties and silage corn yield were determined. Coefficient of variation (CV%) varied from 1.0% (pH) to 38.1% (P2O5) in herbicide not applied plots and from 0.9% (pH) to exchangeable Na (55.1%) in herbicide applied plots. Calcium carbonate, organic matter and clay displayed well defined spatial structure. Sand, pH and electrical conductivity (EC) showed moderate spatial dependency. However, silt, moisture content, bulk density, plant available phosphorus and potassium had weak spatial structure. Silage corn yield distribution map successfully distinguished the three corn hybrids planted. The difference in vegetation period among three corn hybrids was effective in distinguishing the location of hybrids within the field. However, the variability in each of the hybrids blocks was assumed to occur due to the difference in short range soil properties. The longest range values were obtained for silage corn yield at both herbicide applied and herbicide unapplied plots.
Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders:
A Systemic Review
Authors: Fellendorf Frederike T. , Bonkat Nina , Dalkner Nina , Schönthaler Elena M.D. , Manchia Mirko , Fuchs Dietmar , Reininghaus Eva Z.
Published: July 2022

Background:

Indoleamine 2,3-dioxygenase (IDO) activity is induced by cellular immune activation and therefore associated to inflammatory diseases, among others psychiatric disorders. This review aims to elucidate IDO activity reflected by kynurenine (KYN) to tryptophan (TRP) ratio in severe mental disorders.

Methods:

A systematic literature search in MEDLINE and EMBASE was conducted targeting clinical trials in English language measuring KYN/TRP in individuals with a diagnosis of depression, bipolar disorder, or schizophrenia.

Results:

Five out of 15 studies found higher levels of KYN/TRP in depression compared to a control group while the same amount found no difference. Moreover, three studies showed lower levels. In bipolar disorder, four out of six and in psychotic disorders three out of four trials found higher levels in patients compared to controls. There are only two studies comparing KYN/TRP in major depression and bipolar disorder, showing conflicting results. Eight studies focused on associations between KYN/TRP and clinical parameters, whereas two studies found positive correlations between KYN/TRP and severity of depressive symptoms. In contrast, four studies did not show an association. IDO activity during specific psychiatric treatment was analyzed by eight studies.

Conclusion:

In summary, this review demonstrates an inconsistency of findings of studies investigating KYN/TRP in severe mental disorders. Although there are hints that inflammation associated TRP catabolism towards the KYN pathway via elevated IDO activity seems likely, no conclusive statements can be drawn. Presumably, the consideration of influencing factors as inflammatory processes, metabolic activities and psychological/neuropsychiatric symptoms are pivotal for a deeper understanding of the underlying mechanisms.
Molecular Docking Analysis of Adhatoda vasica with Thromboxane A2
Receptor (TXA2R) (6IIU) and Antiviral Molecules for Possible Dengue
Complications
Authors: Thangaraju Pugazhenthan , Narasimhan Gopinathan , Ramamurthy Vijayakumar Arumugam , Gurunthalingam Meenalochini Prakash , Yella Sree Sudha Tanguturi , Venkatesan Sajitha , thangaraju Eswaran
Published: July 2022

Objective:

The present study is an in silico model of platelet amplification potential of
Adhatoda vasica, which can be used to treat thrombocytopenia in dengue complications.

Methods:

Docking studies have proved to be an essential tool that facilitates the structural diversity of
natural products to be harnessed in an organized manner. In the present study, vasicine containing natural
anti-dengue potential was subjected to docking studies using Schrodinger glides software
(ver.11.1). The docking study was carried out to find out the potential molecular targets for selected
protein. The docking was carried out on different ligands, like vasicine, ramatroban, chloroquine,
celgosivir, and standard eltrombopag downloaded from PubChem and retrieved to glide software and
ligands prepared using lig prep wizard. Docking was performed using the ligand docking wizard of
Glide-maestro 2018.

Results:

The docking score of vasicine (-5.27) is nearly identical to the standard eltrombopag (-6.08),
and both ligands bind with one hydrogen bond. The validation score of ramatroban is -12.39, binding
with five hydrogen bonds, Celgosivir exhibited a docking score of -7.3 with three hydrogen bonds, and
chloroquine displayed no hydrogen bond but had a docking score of -4.6.

Conclusion:

Vasicine was found to be the most suitable target of platelet amplification potential from
Adhatoda vasica. However, the molecular docking results are preliminary, and it has been indicated
that vasicine could be one of the potential ligands to treat the thrombocytopenia of dengue; experimental
evaluation will be carried out in the near future.
Current Status and Medicinal Prominence of Arnebia euchroma
(Ratanjot): A Critically Endangered Plant of Trans-Himalayan
Region
Authors: Devi Sunita , Sharma Pooja , Sharma Rohini , Thakur Meena
Published: July 2022

Trans-Himalayan region has been a major component of the India’s opulent medicinal
plant heritage that encompasses numerous critically endangered plant species.
Arnebia euchroma (Royle ex Benth.) Johnston (common name: Ratanjot), a Trans-
Himalayan native, is amongst them, and it belongs to the family Boraginaceae. Ratanjot
has long been used as a colourant in food and cosmetics besides a major ingredient of traditional
remedies prescribed for curing mild constipation, dermatitis, frostbite, and eczema
like health disorders. Though principally harvested for its roots, almost all the parts of this
plant have been used in pharmaceutical products, food, dyes and beverages since prehistoric
times. Its roots are a rich source of naphthoquinone pigment(s) mainly shikonin, acetylshikonin
and deoxyshikonin, accountable for its medicinal value as antimicrobial, wound
healing, anti-inflammatory, anticancer, and antioxidant agent(s). Considering the medicinal
importance and critically endangered status of this taxon, the need of the hour is to conserve
and propagate it for supplying sufficient raw materials for its commercial exploitation.
Brace Prescription for Adult Scoliosis - Literature Review
Authors: Ng Shu Yan , Lung Tai Hong Andrew , Cheng Lok Yan Joanne , Ng Yin Ling Elaine
Published: July 2022

Purpose:

The 2021 SOSORT guidelines stipulated that braces be prescribed for adult scoliosis with chronic pain and progressive curve. Yet, there have been no objective protocols relating to the prescription of the brace. Therefore, this review investigates if there are any objective criteria or generally agreed on protocols for brace prescription in adult scoliosis patients.

Methods:

Relevant papers were searched in PUBMED. Only articles that are in English and cover the clinical aspect of adult scoliosis bracing are included.

Results:

A total of twelve papers were identified. They include different adult scoliosis braces, ranging from elastic belts to rigid braces. The treatment protocol varied tremendously. No objective criteria were found concerning the prescription of a brace, daily wearing time, duration of the intervention, and weaning protocol. The brace treatment was primarily employed to manage low back pain.

Conclusion:

Our search showed no objective criteria and clear indications for bracing and no consensus concerning the prescription of braces, daily wearing time, and duration of the intervention for patients with adult scoliosis.

The authors proposed prescription of a brace be based on more objective radiological criteria and severity of low back pain. Brace prescription should depend on the flexibility of the curve and can range from accommodative to rigid braces of corrective design. “Corrective” brace has to be worn at least 14 hours daily for six months or until the low back pain subsides to the extent that permits daily activities with minimal discomfort. “Accommodative” brace can be worn when required.
Analisis Kesediaan Membayar (Willingness to Pay) Pengunjung dalam Upaya Pengembangan Agrowisata “Sweetberry” di Kabupaten Cianjur
Authors: Pertiwi Tazya Aulia , Noechdijati Dyah , Dharmawan Budi
Published: July 2022

Sekarang ini banyak berkembang tempat wisata bertema yang sama dengan Agrowisata “Sweetberry” di kawasan Cianjur, dengan begitu semakin banyak pesaing. Fasilitas yang ada di Agrowisata “Sweetberry” masih terbilang sangat sederhana sehingga Agrowisata “Sweetberry” ingin melakukan pengembangan untuk dapat bersaing dengan Agrowisata yang ada dikawasan Cianjur dan sekitarnya. Penelitian ini bertujuan untuk: (1) Mengidentifikasi karakteristik pengunjung Agrowisata “Sweetberry”, (2) Mengidentifikasi persepsi pengunjung Agrowisata “Sweetberry”, (3) Menghitung besarnya nilai kesedian membayar (Willingnnes To Pay) dari pengunjung Agrowisata “Sweetberry”,  (4) Mengetahui faktor-faktor yang mempengaruhi nilai Willingness To Pay (WTP) dari pengunjung Agrowisata “Sweetberry”. Metode analisis yang digunakan adalah Analisis Karakteristik dan persepsi pengunjung, Analisis CVM (Contingent Valuation Method), serta Analisis Faktor-faktor yang Mempengaruhi Besarnya Nilai WTP Pengunjung Agrowisata “Sweetberry”. Hasil penelitian menunjukkan: (1) Penelitian berdasarkan segmentasi pengunjung didominasi oleh laki-laki dengan rata-rata usia antara 35 tahun, kemudian status di dominasi oleh konsumen yang sudah menikah, dengan tingkat pendidikan tertinggi adalah 16 tahun atau Strata 1, pekerjaan yang mendominasi adalah pegawai swasta, rata-rata respoden yang memiliki pendapatan sebesar Rp6.862.000, dan jumlah tanggungan yang dimiliki responden sebanyak 3 orang, (2) Persepsi pengunjung Agrowisata “Sweetberry” berdasarkan aspek kognitif, afektif dan konaitif dapat disimpulkan termasuk kedalam kategori setuju dan masing-masing memiliki rata-rata sebesar 3,97; 3,68 dan 3,67, (3) Nilai rata-rata maksimum WTP pengunjung sebesar Rp23.443,038 hal tersebut bertambah sebesar Rp8.443,038 dari tiket masuk awal yang sebesar Rp15.000, (4) Faktor yang mempengaruhi kesediaan membayar secara signifikan pada selang kepercayaan 95% adalah jenis kelamin, tingkat pendidikan, pendapatan, dan jumlah tanggungan.
Proteksi, Ekspansi, dan Subsidi: Upaya Indonesia Menghadapi Tekanan Pasar Gula Dunia
Authors: Soraya Baida , Hartoyo Sri , Siregar Hermanto , Harianto Harianto
Published: July 2022

Sejak 2016 Indonesia telah menjadi negara importir gula nomor satu dunia melampaui Tiongkok. Di tahun 2020, Indonesia terus mengimpor gula hingga sebanyak 4400 ribu MT gula mentah. Penurunan produksi yang disebabkan oleh penyempitan areal tanam membuat Indonesia akan terus mengimpor gula di 2021/22. Tujuan penelitian yaitu mengevaluasi dampak kebijakan proteksi, ekspansi, dan subsidi terhadap industri gula Indonesia. Menggunakan metode simulasi ekonometrika, hasil penelitian menunjukkan bahwa perkembangan luas perkebunan tebu di Pulau Jawa dipengaruhi oleh luas areal tebu tahun sebelumnya. Variabel yang sama ditambah dengan jumlah pabrik penggilingan tebu mempengaruhi luas tanam tebu perkebunan luar Pulau Jawa. Kebijakan proteksi dan subsidi oleh pemerintah mempengaruhi permintaan serta produksi gula Indonesia. Kebijakan ekspansi areal tanam tebu, terutama ke luar Pulau Jawa, merupakan kebijakan yang paling disarankan.
Analisis Faktor Sosial Ekonomi Rumah Tangga terhadap Tingkat Ketahanan Pangan (Kasus pada Gapoktan Tani Sejahtera Desa Ujunggebang Kabupaten Cirebon)
Authors: Apid Apid , Mukson Mukson , Sumekar Wulan
Published: July 2022

Penelitian ini bertujuan untuk menganalisis faktor sosial ekonomi rumah tangga terhadap tingkat ketahanan pangan pada Gapoktan Tani Sejahtera Desa Ujunggebang. Penelitian dilaksanakan pada bulan Maret di Gapoktan Tani Sejahtera yang berlokasi di Desa Ujunggebang Kecamatan Susukan, Kabupaten Cirebon, Jawa Barat. Pemilihan lokasi dilakukan secara purposive didasarkan pada banyaknya anggota yang masih tergolong ke dalam petani miskin. Metode penelitian yang digunakan adalah metode studi kasus. Metode penentuan sampel menggunakan teknik random sampling dengan jumlah sampel sebanyak 7 kelompok dari 14 kelompok. Penentuan sampel petani diambil sebanyak 10 responden tiap kelompok, sehingga secara keseluruhan ada 70 sampel. Metode pengumpulan data primer diperoleh dari wawancara berdasarkan kuesioner terstruktur. Data sekunder diperoleh BPS dan sumber lain yang relevan. Metode analisis data menggunakan analisis regresi linear berganda, dengan variabel dependen tingkat ketahanan pangan, sedangkan variabel independen faktor sosial ekonomi rumah tangga (pendapatan rumah tangga, umur, pendidikan, luas lahan, jumlah tanggungan keluarga, lama bertani dan akses modal). Hasil penelitian menunjukkan bahwa secara bersama-sama variabel independen berpengaruh sangat nyata (P<0,05) terhadap tingkat ketahanan pangan. Hasil ini menunjukkan bahwa perbaikan faktor sosial ekonomi dapat meningkatkan ketahanan pangan
Analisis Tataniaga Garam di Desa Les, Kecamatan Tejakula, Kabupaten Buleleng
Authors: Maharani A.P. Ida Ayu , Anggreni I Gusti Ayu Agung Lies , Listia Dewi Ida Ayu
Published: July 2022

Garam merupakan komoditi yang sangat potensial dan strategis untuk dikembangkan di Indonesia. Desa Les merupakan desa penghasil garam tradisional di Kabupaten Buleleng. Keadaan geografis Desa Les yang dekat dengan pantai menjadi salah satu faktor pendorong bagi masyarakat sekitar untuk melakukan usaha produksi garam. Aspek tataniaga merupakan hal penting dalam mendukung peningkatan pendapatan petani garam. Panjang pendeknya saluran tataniaga mempengaruhi banyaknya lembaga tataniaga yang terlibat dan besarnya biaya tataniaga yang dikeluarkan. Penelitian ini bertujuan untuk mengetahui saluran tataniaga garam, struktur pasar, perilaku pasar garam, dan efisiensi tataniaga garam. Data penelitian ini dianalisis secara kualitatif dan kuantitatif. Responden penelitian berjumlah 20 orang, terdiri dari 10 orang petani dan 10 orang lembaga tataniaga. Penentuan responden petani menggunakan metode Simple Random Sampling sedangkan penentuan jumlah responden lembaga tataniaga menggunakan teknik Snowball Sampling. Hasil dari penelitian ini adalah terdapat empat saluran tataniaga yang terlibat. Struktur pasar garam mengacu pada struktur pasar oligopoli. Saluran tataniaga tingkat 0 merupakan saluran terpendek dan paling efisien dengan margin tataniaga sebesar Rp. 0/kg dan farmer’s share sebesar 100% hal ini disebabkan karna tidak adanya lembaga tataniaga yang terlibat. Rasio keuntungan dan biaya terbesar ada pada saluran 2 yaitu sebesar 1,8.
Evaluasi Penerimaan dan Penggunaan Cyber Extension sebagai Media Informasi oleh Informasi Pertanian
Authors: Wowor Liana Yessi , Cahyono Edi Dwi , Safitri Reza
Published: July 2022

Penelitian ini mengadopsi teori TAM (Technological Acceptance Model), teori untuk mengkaji pemanfaatan Cyber Extension sebagai situs informasi oleh informan penyuluh pertanian. Tujuan untuk menganalisis aspek demografi, akses visibilitas, dan elemen penentu lainnya, serta menguji pengaruh persepsi kegunaan dan persepsi kesederhanaan penggunaan terhadap niat perilaku penyuluh pertanian untuk mengambil dan menggunakan teknologi. Teknik penelitian yang digunakan adalah penelitian deskriptif kuantitatif dengan metode survei, dilakukan dengan wawancara terhadap 76 informan penyuluh pertanian di Dinas Pertanian Kabupaten Minahasa Selatan, Provinsi Sulawesi Utara, antara bulan April sampai Mei 2021. Teknik analisis data menggunakan analisis dan SEM-PLS. Hasil penelitian menemukan bahwa aspek demografi, aspek manfaat yang dirasakan, dan aspek kemudahan penggunaan yang dirasakan semuanya berdampak pada niat perilaku penyuluh pertanian untuk mengambil dan menggunakan Cyber Extension di Kabupaten Minahasa Selatan.
Pengaruh E-WOM pada Media Sosial Instagram terhadap Keputusan Pembelian Produk Sayuran di Bos Sayur Malang yang Dimediasi oleh Kepercayaan Konsumen
Authors: Sibarani Sionly Octa Frisca , Ambayoen Mas Ayu , Prasetyo Hendro
Published: July 2022

Persaingan bisnis produk secara online mendukung pelaku usaha untuk melakukan strategi dalam memikat minat konsumen dengan menerapkan electronic word of mouth (e-WOM) dengan melihat dari persepsi dan interaksi dari pengguna instagram terhadap produk. Penelitian ini bertujuan untuk mengetahui pengaruh variabel intensitas penggunaan media sosial, pendapat konsumen, konten instagram terhadap keputusan pembelian produk sayuran melalui kepercayaan konsumen produk sayuran di Bos Sayur Malang. Total responden dalam penelitian ini berjumlah 98 responden dengan kriteria mengikuti (follow) akun instagram  bossayur.id dan pernah melakukan pembelian produk sayuran di akun instagram  bossayur.id minimal 1 kali pembelian. Metode pengumpulan data menggunakan kuisioner online berupa google form dan wawancara. Teknik analisis data yang digunakan menggunakan alat SEM PLS dan menggunakan software WarpPLS 7.0. Hasil penelitian menunjukkan variabel e-WOM yang terdiri dari intensitas penggunaan media sosial, pendapat konsumen, dan konten instagram berpengaruh secara signifikan terhadap keputusan pembelian melalui kepercayaan konsumen.
Daya Saing Komoditas Vanili Indonesia di Pasar Internasional
Authors: Abdat Humairo Shidiq , Santoso Siswanto Imam , Nurfadillah Suryani
Published: July 2022

Vanili merupakan tanaman perkebunan yang biasa dimanfaatkan sebagai pemberi aroma pada makanan, kosmetik, dan parfum sehingga memiliki nilai jual yang tinggi terutama di luar negeri. Tujuan dari penelitian ini adalah menganalisis daya saing komparatif, daya saing kompetitif, posisi pasar vanili Indonesia di pasar internasional serta potensi vanili Indonesia dalam merebut pasar ekspor. Penelitian ini dilaksanakan pada bulan Maret 2021 hingga April 2021. Penelitian ini menggunakan metode kuantitatif deskriptif. Jenis data yang digunakan dalam penelitian ini adalah data sekunder dengan bentuk data panel periode 2010-2019. Metode analisis data menggunakan Indeks Revealed Comparative Advantage (RCA) dan Acceleration Ratio (AR) digunakan untuk mengetahui keunggulan komparatif dan kemampuan vanili Indonesia dalam merebut pasar ekspor vanili dunia. Metode Export Product Dynamic (EPD) digunakan untuk mengetahui keunggulan kompetitif dan performa suatu komoditas. Hasil penelitian menunjukan bahwa daya saing ekspor vanili Indonesia untuk negara tujuan ekspor Amerika Serikat, Jerman, Prancis, India, dan Belanda memiliki daya saing yang kuat karena rata-rata nilai RCAnya lebih dari satu. Posisi daya saing kompetitif yang sering muncul selama periode 2010 – 2019 pada kelima negara tujuan ekspor tersebut adalah rising star, kemudian lost opportunity, falling star, dan yang paling sedikit muncul adalah retreat. Komoditas vanili Indonesia dapat merebut pasar internasional karena memiliki nilai hasil perhitungan AR lebih dari satu dan dapat mengalahkan negara-negara pesaingnya yang memiliki nilai AR dibawah Indonesia seperti Belgia, Mauritius, Kanada, dan Turki, namun masih belum mampu mengalahkan pesaing utamanya yaitu Madagaskar yang memiliki nilai AR jauh diatas Indonesia
Analisis Pengendalian dan Perhitungan Nilai Akhir Persediaan Bahan Baku pada Agroindustri Tahu House of Tofu Bandar Lampung
Authors: Ramadhanti Anindya , Kasymir Eka , Situmorang Suriyaty
Published: July 2022

Bahan baku adalah komponen terpenting pada suatu proses produksi.  Proses produksi dapat berjalan apabila bahan bakunyaa terpenuhi, maka diperlukan ketelitian dalam mengelola dan mengendalikan persediaan bahan baku sebagai bahan pertimbangan dalam menentukan kuantitas persediaan yang efisien.  Tujuan penelitian ini untuk mengetahui jumlah persediaan bahan baku optimal, persediaan pengaman, titik pemesanan kembali, serta persediaan maksimum pada Agroindustri Tahu House of Tofu. berdasarkan metode EOQ (Economic Order Quantity) dan menghitung nilai persediaan akhir bahan baku pada Agroindustri Tahu House of Tofu berdasarkan metode FIFO (First in First Out).  Metode penelitian yang digunakan adalah metode studi kasus.  Hasil penelitian menunjukkan bahwa pengendalian persediaan bahan baku pada Agroindustri Tahu House of Tofu sudah cukup baik dan optimal karena tidak pernah mengalami kekosongan bahan baku.  Total biaya persediaan bahan baku tahu dengan model EOQ menunjukkan bahwa biaya persediaan yang dikeluarkan lebih kecil dibandingkan kebijakan perusahaan dengan penghematan sebesar Rp12.233 per tahun.  Agroindustri tahu House of Tofu sebaiknya meningkatkan sistem pengendalian persediaan bahan bakunya dengan model EOQ agar anggaran persediannya dialokasikan untuk keperluan lainnya yang lebih menguntungkan.
Pengukuran Efisiensi Teknis dengan Pendekatan Fungsi Produksi Stochastic Frontier Translog pada Usahatani Bawang Merah
Authors: Laili Zainatul , Fauziyah Elys
Published: July 2022

Bawang merah termasuk komoditas hortikultura yang jumlah permintaannya sangat  tinggi, karena komoditas tersebut dibutuhkan sebagai salah satu komponen dalam setiap masakan.  Kabupaten Sumenep merupakan wilayah yang berpotensi menghasilkan bawang merah, tepatnya di Desa Basoka Kecamatan Rubaru. Namun, dalam dua tahun terakhir produktivitas bawang merah tersebut cenderung menurun. Riset ini dimaksudkan untuk menganalisis input yang berpengaruh terhadap tingkat produksi bawang merah dan mengukur tingkat efisiensi petaninya di Desa Basoka. Metode analisis didekati dengan Fungsi Produksi Stochastic Frontier Translog, terhadap  120 sampel. Hasil riset memberikan gambaran bahwa terdapat tiga jenis input yang dapat berpengaruh terhadap hasil panen budidaya bawang merah yaitu benih, pupuk ZA, dan pupuk kandang. Tingkat efisiensi teknis sangat bervariasi, dimulai dari petani yang sangat tidak efisien dengan tingkat efisiensi sebesar 0,11 sampai dengan petani yang sangat efisiensi, yang tingkat efisiensinya mencapai 0.99. Namun secara keseluruhan sebanyak 63 persen petani bawang merah di Desa Basoka telah mampu berproduksi secara efisien.
Research on technology contribution evaluation model for commercialization
Authors:   Division of Convergence Business, Korea University, Seoul, South Korea, Kim Heung Su
Published: July 2022

The purpose of this study is to calculate the quantitative and qualitative contribution of intellectual property rights owned by startups for successful commercialization. In the 4th industrial revolution economy, intellectual property rights, which play an important role in job creation and economic growth, play a very important role for startups. In particular, intellectual property rights are the most important asset for startups, and it is necessary to promote the sustainable growth of startups through efficient intellectual property management. This study evaluated the relative contribution of technology, human resources, and market assets, which are the sources of intangible assets for successful business start-ups through intellectual property transfer and technology trade. The contribution of the case companies to intangible assets was calculated by comprehensively judging four technologies related to each other. To this end, we find a strategy for the successful commercialization of intellectual property rights owned by startups by calculating the relative contribution of technical assets, human assets, and market assets, which are the sources of intangible assets. The contribution of the example company to intangible assets is calculated by comprehensively judging the four related intellectual property rights of the startup. In future research, we look forward to a follow-up study that can help companies make strategic decisions by comparing and analyzing various companies in consideration of industry and size.