bluuebunny/crossref_metadata_2025 huggingface dataset:
Voters Use Campaign Finance Transparency and Compliance Information
Authors: Wood Abby K.
Published: February 2022

Campaign finance compliance and transparency reveal important non-policy attributes that voters care about. Using vignette and conjoint survey experiments, I show that voters in primary elections incorporate transparency and compliance considerations into candidate selection. This effect persists even where the candidate shares the respondents’ preferred policy positions. The findings bring campaign finance transparency and compliance into the scholarly conversation about candidate valence. They also have implications for our campaign finance jurisprudence and suggest that courts should expand their understanding of the informational benefits of campaign finance disclosures and compliance information.
Competition and Fan Substitution Between Professional Sports Leagues
Authors: Wallrafen Tim , Nalbantis Georgios , Pawlowski Tim
Published: February 2022

A peculiarity in professional sports is the fact that leagues regularly hold monopoly powerwithin their sports.However, whether and to what extent these leagues may compete with other leaguesacross sportsis relatively unexplored. This paper contributes to the literature by analyzing competition and fan substitution in Germany, where top-tier league managers in handball, basketball, and ice hockey have recently claimed that their teams suffer from football’s dominant position. Our attendance demand models confirm the existence of significant substitution effects in this setting, which suggests that leagues indeed do compete economicallyacross sportsfor fan attendance.
Assessment of the Living Conditions in Polish and German Transborder Regions in the Context of Strengthening Territorial Cohesion in the European Union: Competitiveness or Complementation?
Authors: Gwiaździńska-Goraj Marta , Jezierska-Thöle Aleksandra , Dudzińska Małgorzata
Published: February 2022

The European Union's regional policy aims to strengthen economic, social, and territorial cohesion and equal space development opportunities. It is an action linking UE that emphasises the problem of cohesion in the interregional context. The essence of territorial cohesion is the necessity to eliminate inequalities between the living conditions of the population. The concept of quality of life is ambiguous, multidimensional and interdisciplinary. This problem is of particular importance concerning border areas, i.e. the periphery of countries, which often adversely affects the population's standard of living. The article aimed to assess the living conditions and the direction of changes in those terms on the Polish-German border, an internal border of the EU (former Eastern Bloc countries). The analysis covered the years 2004–2019. The impact of the EU's regional development and cohesion policies for border areas (INTERREG) in improving the analysed regions' living conditions was also determined. The method of aggregation, standardised sums, was used in the analysis. The research showed that the level of living conditions of these border regions' population was spatially diversified, being more favourable on the German side. The analysed border regions had less favourable material and non-material living conditions than the countries' average value. Significant changes in the living conditions of border regions in the years 2004–2019 were established towards equalising the quality of life, which was influenced by the spatial policy of territorial cohesion.
A framework for the analysis of self-confirming policies
Authors: Battigalli P. , Cerreia-Vioglio S. , Maccheroni F. , Marinacci M. , Sargent T.
Published: February 2022

This paper provides a general framework for analyzing self-confirming policies. We study self-confirming equilibria in recurrent decision problems with incomplete information about the true stochastic model. We characterize stationary monetary policies in a linear-quadratic setting.
Soil properties across a hydrological gradient in saladas from northeast Spain: what are the implications for soil carbon stocks, CO2 efflux and microbial communities in a warming world?
Authors: Thomas A. D. , Tooth S. , Lan S. , Holt T. , Saunders I. , Tarren H.
Published: February 2022

Numerous permanent and temporary wetlands occur throughout the world’s drylands. Although characterised by diverse water inundation frequencies, durations and depths, these wetlands in drylands are typically hotspots of biological activity and productivity. The healthy functioning and even existence of many wetlands in drylands, however, is threatened by desiccation resulting from a combination of climate change and human disturbance. Near Alcañiz in arid northeast Spain, three adjacent saladas (playas) with contrasting hydroperiods provide an opportunity to investigate how moisture availability affects their soil carbon (C) stocks, CO2efflux, and microbial communities. Predicting the impacts of changes in moisture availability on the C cycle in wetlands in drylands is challenging but important because many contain large C stocks and may be significant sources and sinks of greenhouse gases. Frequent inundation and/or near-permanent soil water saturation supports the generation of organic C from a range of different sources. Soil inorganic C was greatest on the driest salada (3.8%) compared to the wetter saladas (3.0% and 2.1%) owing to evaporative concentration and the reaction of CO2with available Ca2+, Mg2+and Na+ions. CO2efflux was greatest at intermediate moisture levels (142 mg CO2 m−2 h−1), but the spatial and temporal variability in CO2efflux on salada surfaces is large, demonstrating the need for intensive sampling regimes to provide realistic estimates of their contribution to atmospheric CO2exchanges. Different microbial community structures also characterise each salada. The saladas near Alcañiz, and many other similar features in northeast Spain, are renowned for their rare and threatened flora and fauna, yet their soil C cycle characteristics and soil microbial communities provide additional reasons to monitor the impacts of climate change and protect these vulnerable environments from further anthropogenic disturbances.
A Censored Mixture Model for Modeling Risk Taking
Authors: Dijkstra Nienke F. S. , Tiemeier Henning , Figner Bernd , Groenen Patrick J. F.
Published: February 2022

Risk behavior has substantial consequences for health, well-being, and general behavior. The association between real-world risk behavior and risk behavior on experimental tasks is well documented, but their modeling is challenging for several reasons. First, many experimental risk tasks may end prematurely leading to censored observations. Second, certain outcome values can be more attractive than others. Third, a priori unknown groups of participants can react differently to certain risk-levels. Here, we propose the censored mixture model which models risk taking while dealing with censoring, attractiveness to certain outcomes, and unobserved individual risk preferences, next to experimental conditions.
Virtual indoor-GPS for measurement uncertainty determination in reconfigurable environments
Authors: Nicksch Christoph , Sabzehi Mielad , Schmitt Robert H.
Published: February 2022

In Line-less Mobile Assembly Systems, the mobilization of assembly resources and products enables rapid physical system reconfigurations to increase flexibility and adaptability. The clean floor approach discards fixed anchor points, so that assembly resources such as mobile robots and automated guided vehicles transporting products can adapt to new products and form new processes. Associated challenges are accurate spatial referencing between mobile resources to meet assembly tolerance requirements. There is a need for more accurate positioning data to locate and navigate mobile assembly resources. An indoor-GPS, as a distributed large-scale metrology system, is able to cover a wide shop floor area and to obtain positioning data with uncertainties in the submillimeter range. The measurement uncertainty of such a system depends on the spatial distribution of the transmitters and the receiver positions. To be able to validate positioning tolerance requirements of an assembly process, measurement uncertainties must be determined. Virtual measurements simulate measurement processes and model dependencies between the environment and the metrology system. This work presents a novel approach for a virtual indoor-GPS to determine measurement uncertainties during a process and to evaluate the measurement process capability. Experiments show the validity of the virtual indoor-GPS which can be used as a planning tool for metrology system setups within Line-less Mobile Assembly Systems.
Discontinuation of Tyrosine Kinase Inhibitors in Patients with Chronic Myeloid Leukemia: a Review of the Biological Factors Associated with Treatment-Free Remission
Authors: Stuckey Ruth , López Rodríguez Juan Francisco , Gómez-Casares María Teresa
Published: February 2022

Purpose of Review

Clinical factors alone do not enable us to differentiate which patients will maintain treatment-free remission (TFR) from those who are likely to relapse. Thus, patient-specific factors must also play a role. This review will update the reader on the most recent studies presenting biological factors that can help predict tyrosine kinase inhibitor (TKI) discontinuation success.

Recent Findings

Cellular and molecular factors with a suggested role in TFR include immune factors and leukemic stem cell (LSC) persistence; the BCR::ABL1 transcript type, halving time, and BCR::ABL1 DNA and RNA positivity; as well as other molecular factors such as somatic mutations, RNA expression, and telomere length.

Our review presents several biomarkers with predictive value for TFR but also highlights areas of unmet need. Future discontinuation guidelines will likely include biological factors for the personalization of TFR prediction. However, it will be important that such advances do not prevent more patients from making a TKI discontinuation attempt.
An explanatory model of the relationships between sport motivation, anxiety and physical and social self-concept in educational sciences students
Authors: Melguizo-Ibáñez E. , Zurita-Ortega F. , Ubago-Jiménez J. L. , López-Gutiérrez C. J. , González-Valero G.
Published: February 2022

Motivation plays a key role in the physical-sports field, in the control of disruptive states and in the mental image that people have of themselves. In view of the above, the present study reflects the objectives of identifying and establishing the relationship between sport motivation, anxiety, physical self-concept and social self-concept, broken down into (a) developing an explanatory model of sport motivation and its relationship with anxiety and social and physical self-concept and (b) contrasting the structural model by means of a multi-group analysis according to sex. To this end, a quantitative, non-experimental (ex post facto), comparative and cross-sectional study was carried out on a sample of 556 students (23.06 ± 6.23). The instruments used were an ad hoc questionnaire, the Spanish version of the Perceived Motivational Climate in Sport Questionnaire (PMCSQ-2), the Beck Anxiety Inventory (BAI) and the Self-Concept Form-5. The results show that the male sex orients sport motivation towards climate, obtaining higher levels of anxiety, however, the female sex, anxiety has a negative impact on the development of social self-concept. In conclusion, it can be affirmed that gender is a fundamental factor in the orientation of sport practice, as well as the development of anxiety and physical and social self-concept.
Allograft Labral Reconstruction of the Hip: Expanding Evidence Supporting Greater Utilization in Hip Arthroscopy
Authors: White Brian J. , Constantinides Shannon M.
Published: February 2022

Purpose of Review

The current review investigates outcomes and failure rates associated with arthroscopic circumferential allograft labral reconstruction of the hip, both as a revision and primary procedure in treating femoroacetabular hip impingement and labral-related pathology.

Recent Findings

Numerous studies within the last decade have demonstrated excellent patient-reported outcomes, high rates of return-to-play in athletes, and low failure rates in patients having undergone arthroscopic circumferential allograft labral reconstruction of the hip. Removal of chronically diseased and injured labral tissue can eliminate a significant pain-generator from the hip joint. Additionally, circumferential reconstruction of the labrum restores the hoop fiber strength and fluid seal akin to what would be seen with native, healthy labral tissue. Recent research has shown that arthroscopic circumferential allograft labral reconstruction may be used not only in the revision setting, but as a primary procedure. Circumferential labral reconstruction should be considered when a surgeon feels that the labrum is irreparable or has failed previous repair.

Arthroscopic circumferential allograft labral reconstruction of the hip can be utilized as treatment option not only in revision settings, but also in primary treatment for femoroacetabular impingement and labral pathology
Contemporary family sponsorship and older parent reunification immigration under New Zealand’s neoliberal immigration regime
Authors: Liu Liangni Sally , Ran Guanyu Jason
Published: February 2022

A neoliberal immigration regime often takes an “economic” lens to frame and reframe immigration regulation based on a rational cost–benefit analysis of what immigration might bring to immigration-receiving countries. Under such a regime, skilled and business immigration is framed as an “economic” immigration category, which can channel in financial and human capital, while family and international humanitarian immigration is regarded as a “social” immigration category assumed to produce immigrants who are more dependent and not able to bring immediate and direct economic gain for immigrant-receiving countries. In New Zealand (NZ), such a neoliberal trend is very much alive within its contemporary immigration policy development. The paper aims to illustrate the neoliberal trend of NZ immigration policy that relates to the entry of immigrants’ family members, especially the older parents. In order to achieve this goal, a detailed review of the evolving NZ family immigration policy over the last three decades and a descriptive analysis of NZ family immigration intake will be presented. By combining the policy review and descriptive analysis together, the paper can inform a better understanding of how the neoliberal immigration regime has had an impact on the patterns of family immigration in NZ.
Organosolv pretreatment of oat husk using oxalic acid as an alternative organic acid and its potential applications in biorefinery
Authors: Sar Taner , Arifa Vina Hasna , Hilmy Muhammad Raihan , Ferreira Jorge A. , Wikandari Rachma , Millati Ria , Taherzadeh Mohammad J.
Published: February 2022

In this study, ethanol organosolv treatment of oat husk and the potential effects of phosphoric acid and oxalic acid as alternatives to sulfuric acid were investigated. These acids were determined as effective as sulfuric acid to obtain high quality lignin and glucan and they can be used instead of sulfuric acid in solvent acidification. To determine the purity and recovery of both lignin and glucan, the effects of initial substrate amount, solid-to-liquid ratio, and amount of washing solutions were also examined using a one-factor-at-a-time strategy. Reducing the amount of washing solutions (water, solvent, or both) negatively affected lignin recovery, but it did not affect glucan recovery. The optimum conditions for pretreatment of the oat husk at higher glucan recovery were obtained with 50% aqueous ethanol acidified with oxalic acid at 210 °C for 90 min and solid-to-liquid ratio of 1:2. In the mixture of evaporated glucan-rich and hemicellulose-rich fractions obtained through the optimized condition, 4.62 g/L biomass containing 10.27% protein was produced by the cultivation of Aspergillus oryzae. The fractions obtained from organosolv treatment can be used to obtain value-added products such as biomass production, and thus contributing to a sustainable economy by integrating lignocellulosic substrate residues into the biorefinery.
Development of a Method for Assessing Country-Based Flood Risk at the Global Scale
Authors: Imamura Yoshiyuki
Published: February 2022

International frameworks such as the Sustainable Development Goals and the Sendai Framework for Disaster Risk Reduction 2015−2030 require the quantification of country-based flood risk. However, few approaches at the global scale include the three necessary components (hazard, exposure, and vulnerability) for determining disaster risk and are country-based assessments, owing to major challenges such as limited data availability and vulnerability proxy selection. Therefore, in this study, a method was developed with the following features: Incorporating the hazard, exposure, and vulnerability components; Applicable to the vast majority of countries in the world; Visualizing priority countries and illustrating effective measures and strategies; Clear and easy to understand by leaders and decision makers of international organizations, governments, and other stakeholders; Identifying each country’s challenges and providing guidance on specific issues for more detailed investigation and policy creation; Including more extensive factors compared with past studies. In Asia and the Pacific, the Flood Risk Index computed by the developed method is compared with the fatality ratio, and the results show that improving flood resilience secures people and society regardless of the magnitude and frequency of floods. Analysis at the global scale visualizes regional tendencies and indicates that countries closer to the equator have higher flood risk. Analysis of country-based flood risk based on five indicators demonstrates that the developed method can assist international organizations, governments, and other stakeholders to further examine country-specific conditions and establish and implement policies and strategies toward building a resilient society and achieving international targets.
Preferred Attributes of Care Pathways for Obstructive Sleep Apnoea from the Perspective of Diagnosed Patients and High-Risk Individuals: A Discrete Choice Experiment
Authors: Natsky Andrea N. , Vakulin Andrew , Chai-Coetzer Ching Li , McEvoy R. Doug , Adams Robert J. , Kaambwa Billingsley
Published: February 2022

Background

The current healthcare system is challenged with a large and rising demand for obstructive sleep apnoea (OSA) services. A paradigm shift in OSA management is required to incorporate the preferences of diagnosed patients and individuals at high risk of OSA.

Objectives

This study aimed to provide empirical evidence of the values and preferences of individuals diagnosed with OSA and high-risk populations regarding distinct OSA care pathway features.

Methods

A discrete choice experiment was undertaken in two groups: those with a formal diagnosis of OSA (n = 421) and those undiagnosed but at high risk of having OSA (n = 1033). Participants were recruited from a large cross-sectional survey in Australia. The discrete choice experiment approach used mixed-logit regression models to determine preferences relating to eight salient features of the OSA management pathway, i.e. initial assessment provider, sleep study setting, diagnosis costs, waiting times, results interpretation, treatment options, provider of ongoing care and frequency of follow-up visits.

Results

The findings indicate that all eight attributes investigated were statistically significant factors for respondents. Generally, both groups preferred low diagnostic costs, fewer follow-up visits, minimum waiting time for sleep study results and sleep specialists to recommend treatment. Management of OSA in primary care was acceptable to both groups and was the most preferred option by the high-risk group for the initial assessment, sleep study testing and ongoing care provision.

Conclusions

The discrete choice experiment results offer a promising approach for systematic incorporation of patient and high-risk group preferences into the future design and delivery of care pathways for OSA management.
The Impacts of Car-Free Days and Events on the Environment and Human Health
Authors: Glazener Andrew , Wylie James , van Waas Willem , Khreis Haneen
Published: February 2022

Purpose of review

In this paper, we seek to elucidate the impact of car-free days and events on human health. Car-free days and events are often designed to alleviate the impact of transportation-related air pollution, noise, physical inactivity, traffic congestion, or other detrimental externalities of private motor vehicle travel. We reviewed existing peer-reviewed and gray literature to understand the variety of potential public health impacts that have been measured as a result of car-free days or events and associated changes in environmental exposures and lifestyles.

Recent findings

The impacts of car-free days and events are highly variable and seem to depend on the scope (frequency, duration, and geographic size) and goals of each car-free day and event. Most of the existing literature measures impacts in terms of air and noise pollution and some studies focus on physical activity metrics. In some cases, car-free days and events were successful in reducing the concentration of certain air pollutants but had little or adverse impacts on the concentration of others. Often, traffic is diverted from cordoned areas to surrounding streets, displacing traffic congestion and adverse environmental exposures to other areas of a city, with potential understudied implications to environmental justice.

Car-free days and events are often an attractive policy option; however, they require intensive planning to be successful. The organization and execution of car-free days and events, as well as public support and stakeholder engagement, greatly influence the level of success and the sustainability of such initiatives. Health benefits may be a palatable and convincing argument to the general public. However, very few studies focus on actual health impacts associated with car-free days and events. Future research could be most useful if it focused on measuring health outcomes associated with car-free days and events through longitudinal studies.
Putting the BRI in Perspective: History, Hegemony and Geoeconomics
Authors: Beeson Mark , Crawford Corey
Published: February 2022

If successfully realised, the Belt and Road Initiative will be the most ambitious and expansive developmental project the world has ever seen. It is not, however, unprecedented. In the aftermath of the Second World War the United States developed what was then an equally unprecedented and ambitious initiative designed to simultaneously facilitate the (re)development of some of the world’s key economies and reinforce its own position as the leader of the western world. Both the American Marshall Plan and China’s BRI are important expressions of geoeconomic influence and power. This paper compares the two projects from the perspectives of ‘hegemonic transitions’ and ‘comparative hegemony’ in order to highlight some striking similarities and noteworthy differences, and gauge the prospects for the BRI and its possible scenarios. Comparatively speaking, the BRI does not have the same sort of compelling geopolitical imperatives and narrative that the emerging Cold War provided for American hegemonic leadership. The Chinese project also lacks the comprehensive global institutional architecture developed in the aftermath of the Second World War that facilitated American influence. Consequently, it may prove more difficult for China to utilise the BRI to translate potential geoeconomic leverage into the sort of hegemonic influence that the US enjoyed during the Cold War, despite its unparalleled ambitions.
Measurement Comparability of Electronic and Paper Administration of Visual Analogue Scales: A Review of Published Studies
Authors: Byrom Bill , Elash Celeste A. , Eremenco Sonya , Bodart Serge , Muehlhausen Willie , Platko Jill V. , Watson Chris , Howry Cindy
Published: February 2022

Background

Visual analogue scales (VASs) are used in a variety of patient-, observer- and clinician-reported outcome measures. While typically included in measures originally developed for pen-and-paper completion, a greater number of clinical trials currently use electronic approaches to their collection. This leads researchers to question whether the measurement properties of the scale have been conserved during the migration to an electronic format, particularly because electronic formats often use a different scale length than the 100 mm paper standard.

Methods

We performed a review of published studies investigating the measurement comparability of paper and electronic formats of the VAS.

Results

Our literature search yielded 26 studies published between 1997 and 2018 that reported comparison of paper and electronic formats using the VAS. After excluding 2 publications, 23 of the remaining 24 studies included in this review reported electronic formats of the VAS (eVAS) and paper formats (pVAS) to be equivalent. A further study concluded that eVAS and pVAS were both acceptable but should not be interchanged. eVAS length varied from 21 to 200 mm, indicating that 100 mm length is not a requirement.

Conclusions

The literature supports the hypothesis that eVAS and pVAS provide comparable results regardless of the VAS length. When implementing a VAS on a screen-based electronic mode, we recommend following industry best practices for faithful migration to minimise the likelihood of non-comparability with pVAS.
Power and Regions in Ancient States
Authors: Feinman Gary M. , Moreno García Juan Carlos
Published: February 2022

The aim of the Element is to provide a comprehensive comparison of the basic organization of power in Mesoamerica and Egypt. How power emerged and was exercised, how it reproduced itself, how social units (from households to cities) became integrated into political formation and how these articulations of power expanded and collapsed over time. The resilience of particular areas (Oaxaca, Middle Egypt), to the point that they preserved a highly distinctive cultural personality when they were included or not within states, may provide a useful guideline about the basics of integration, negotiation and autonomy in the organization of political formations.
Purely Probabilistic Measures of Explanatory Power: A Critique
Authors: Roche William , Sober Elliott
Published: February 2022

All extant purely probabilistic measures of explanatory power satisfy the following technical condition: if Pr(E | H1) > Pr(E | H2) and Pr(E | ∼H1) < Pr(E | ∼H2), then H1’s explanatory power with respect to E is greater than H2’s explanatory power with respect to E. We argue that any measure satisfying this condition faces three serious problems—the Problem of Temporal Shallowness, the Problem of Negative Causal Interactions, and the Problem of Nonexplanations. We further argue that many such measures face a fourth problem—the Problem of Explanatory Irrelevance.
Limpet larvae (Patella aspera Röding, 1798), obtained by gonad dissection and fecundation in vitro, settled and metamorphosed on crustose coralline algae
Authors: Castejón Diego , Nogueira Natacha , Andrade Carlos A.P.
Published: February 2022

The limpet Patella aspera Röding, 1798, is a native species from the Macaronesian region whose fishing is regulated. The early life of limpets, including the settlement process, is poorly known thus far. The current study evaluated different substrates to induce settlement in P. aspera, including microalgae strains (Halamphora coffeaeformis, Navicula incerta and Pavlova sp.) and crustose coralline algae (CCA) obtained from limpet shells. The results showed that gametes obtained by dissection and matured artificially using alkalinized seawater baths can produce viable larvae able to metamorphose to juveniles. Feeding was not required during larval development, suggesting lecithotrophy. Early postlarvae were identified by the shedding of the velum, and juveniles were identified by teleoconch and active grazing behaviour. The presence of CCA shortened the timing for settlement and increased the ratio of juveniles. The type and abundance of CCA can influence settlement success. Moreover, the results suggested that settlement and metamorphosis in true limpets (Patellogastropoda) might be triggered by a two-step mechanism, i.e. a first cue influencing the shift between swimming and crawling activity and a second cue determining settlement and metamorphosis to early postlarvae and juveniles.
Psychologists should learn structural specification and experimental econometrics
Authors: Ross Don
Published: February 2022

The most plausible of Yarkoni's paths to recovery for psychology is the least radical one: psychologists need truly quantitative methods that exploit the informational power of variance and heterogeneity in multiple variables. If they drop ambitions to explain entire behaviors, they could find a box full of design and econometric tools in the parts of experimental economics that don't ape psychology.
The four different modes of psychological explanation, and their proper evaluative schemas
Authors: Gilead Michael
Published: February 2022

I apply Benjamin's (1941) taxonomy of common scientific “modes of explanation” to the psychological context. I argue that: (i) in a “naming” mode, generalizability is not necessary; (ii) in an “analysis,” generalizability is desired; (iii) in a “causal ontology,” generalizability is merely one of the means to an end (theory-challenge); (iv) in a “synthesis,” generalizability is (eventually) critical. A better appreciation of the diversity in psychologists' modes of explanation is crucial for cogent meta-psychological discussions.
The stimulus-response crisis
Authors: Wilford Robyn , Ardila-Cifuentes Juan , Baggs Edward , Anderson Michael L.
Published: February 2022

Yarkoni correctly recognizes that one reason for psychology's generalizability crisis is the failure to account for variance within experiments. We argue that this problem, and the generalizability crisis broadly, is a necessary consequence of the stimulus-response paradigm widely used in psychology research. We point to another methodology, perturbation experiments, as a remedy that is not vulnerable to the same problems.
Increasing generalizability via the principle of minimum description length
Authors: Bonifay Wes
Published: February 2022

Traditional statistical model evaluation typically relies on goodness-of-fit testing and quantifying model complexity by counting parameters. Both of these practices may result in overfitting and have thereby contributed to the generalizability crisis. The information-theoretic principle of minimum description length addresses both of these concerns by filtering noise from the observed data and consequently increasing generalizability to unseen data.
We need to be braver about the generalizability crisis
Authors: Braver Todd S. , Braver Sanford L.
Published: February 2022

We applaud the effort to draw attention to generalizability concerns in twenty-first-century psychological research. Yet we do not feel that a pessimistic perspective is warranted. We outline a continuum of available methodological tools and perspectives, including incremental steps and meta-analytic approaches that can be readily and easily deployed by researchers to advance generalizability claims in a forward-looking manner.
Measurement practices exacerbate the generalizability crisis: Novel digital measures can help
Authors: Davidson Brittany I. , Ellis David A. , Stachl Clemens , Taylor Paul J. , Joinson Adam N.
Published: February 2022

Psychology's tendency to focus on confirmatory analyses before ensuring constructs are clearly defined and accurately measured is exacerbating the generalizability crisis. Our growing use of digital behaviors as predictors has revealed the fragility of subjective measures and the latent constructs they scaffold. However, new technologies can provide opportunities to improve conceptualizations, theories, and measurement practices.
The influence of organisational safety resource-related activities and other exploratory variables on seafarers’ safety behaviours
Authors: Mišković Darijo , Ivče Renato , Hess Mirano , Đurđević-Tomaš Ivica
Published: February 2022

Inadequate human actions are still the main cause of all reported accidents and incidents on board ships. The aim of this study is to explore the influence of safety resource activities and other exploratory variables on seafarers’ safety behaviour. For this study, a series of open-ended interviews were conducted to gain insight into how shipping organisations struggle with this issue. Following the interviews, a questionnaire was prepared and distributed to professional seafarers. Two exploratory factor analyses were conducted to identify the underlying factor structure and five factors emerged. Furthermore, three hierarchical multiple regression analyses were conducted to examine the influence of the factors obtained, namely, Company safety orientation and Additional safety incentives on seafarers’ perceived Safety awareness, Job satisfaction, Risk acceptance and other exploratory variables. The study shows that the perceived resource-related activities of the organisation and the demographic characteristics of the respondents can influence the safety behaviour of seafarers.
Race, Post-Reconstruction Politics, and the Birth of Federal Support for Black Colleges
Authors: ROSE DEONDRA
Published: February 2022

In 1890, Congress passed the Second Morrill Land-Grant Act, which provided federal resources to support the creation of nineteen Black land-grant colleges. At a historical and political moment when Black Americans faced a violently repressive backlash against what progress they had achieved during Reconstruction, the successful passage and implementation of this legislation was unlikely. How did congressional lawmakers successfully pass the Morrill Land-Grant Act of 1890, and was the expansion of educational opportunity for African Americans a clearly expressed objective? Using historical analysis of primary sources, this analysis suggests that the 1890 legislation’s investment in Black colleges reflected a politically expedient compromise between northern Radical Republicans who supported greater educational access for Black citizens and Southern Democrats who wished to expand higher educational opportunity in their region while also maintaining the segregated racial order of southern educational institutions.
Incursion of H5N8 high pathogenicity avian influenza virus (HPAIV) into gamebirds in England
Authors: Brookes Sharon M. , Mansfield Karen L , Reid Scott M. , Coward Vivien , Warren Caroline , Seekings James , Brough Tanis , Gray Davina , Núñez Alejandro , Brown Ian H.
Published: February 2022

The 2016–17 European outbreak of H5N8 HPAIV (Clade 2.3.4.4b) affected a wider range of avian species than the previous H5N8 outbreak (2014–15), including an incursion of H5N8 HPAIV into gamebirds in England. Natural infection of captive-reared pheasants (Phasianus colchicus) led to variable disease presentation; clinical signs included ruffled feathers, reluctance to move, bright green faeces, and/or sudden mortality. Several birds exhibited neurological signs (nystagmus, torticollis, ataxia). Birds exhibiting even mild clinical signs maintained substantial levels of virus replication and shedding, with preferential shedding via the oropharyngeal route. Gross pathology was consistent with HPAIV, in gallinaceous species but diphtheroid plaques in oropharyngeal mucosa associated with necrotising stomatitis were novel but consistent findings. However, minimal or modest microscopic pathological lesions were detected despite the systemic dissemination of the virus. Serology results indicated differences in the timeframe of exposure for each case (n = 3). This supported epidemiological conclusions confirming that the movement of birds between sites and other standard husbandry practices with limited hygiene involved in pheasant rearing (including several fomite pathways) contributed to virus spread between premises.
Occurrence of Warm Freezing Rain: Observation and Modeling Study
Authors: Lu Zhengqi , Han Yongxiang , Liu Yangang
Published: February 2022

Freezing rain has been normally considered to be composed of supercooled raindrops when the 2 m air temperature (hereafter ) is below freezing. However, according to a statistical survey of freezing rain observations in China from 2000 to 2019, we find that there were 656 events that occurred at greater than 0°C (hereafter warm freezing rain and denoted by WFR), which account for 7% of the total freezing rain observations. Additionally, nearly 3% (266 observations) of freezing rain events occurred when the near‐surface wet‐bulb temperature was greater than 0°C. The modeling and sensitivity experiments on the nonequilibrium raindrop temperature (hereafter ) show that the temperature difference between raindrops and the atmosphere is the main cause of WFR. The magnitudes of the (difference between raindrop temperature and air temperature ) and (difference between and wet‐bulb temperature ) are determined by the raindrop diameter D, temperature lapse rate Г, and relative humidity RH. Increases of D and Г, and a decrease of RH enhance and and thus the occurrence of WFR. Further simulations of 4 idealized and 370 real sounding profiles reveal that either the or the cannot properly distinguish the WFR events. When considering the temperature difference between raindrops and the atmosphere, the WFR can form by the “melting of solid hydrometeors” or “supercooled warm rain process.” This study can also deepen our understanding of the conditions of WFR and freezing rain formation at different altitudes.
SU-8 cantilever with integrated pyrolyzed glass-like carbon piezoresistor
Authors: Jang Jongmoon , Panusa Giulia , Boero Giovanni , Brugger Juergen
Published: February 2022

Glass-like carbon (GC) is a nongraphitizing material composed entirely of carbon atoms produced from selected organic polymer resins by controlled pyrolysis in an inert atmosphere. The GC properties are a combination of the properties of glass, ceramic, and graphite, including hardness, low density, low thermal conductivity, high chemical inertness, biocompatibility, high electrical conductivity, and microfabrication process compatibility. Despite these unique properties, the application of GC in mechanical sensors has not been explored thus far. Here, we investigate the electrical, structural, and chemical properties of GC thin films derived from epoxy-based negative photoresist SU-8 pyrolyzed from 700 to 900 °C. In addition, we fabricated microGC piezoresistors pyrolyzed at 700 and 900 °C and integrated them into nonpyrolyzed SU-8 cantilevers to create microelectromechanical systems (MEMS) mechanical sensors. The sensitivities of the GC sensor to strain, force, surface stress, and acceleration are characterized to demonstrate their potential and limits for electromechanical microdevices.
Genotype-phenotype correlation of renal lesions in the tuberous sclerosis complex
Authors: Muto Yoshinari , Sasaki Hitomi , Sumitomo Makoto , Inagaki Hidehito , Kato Maki , Kato Takema , Miyai Shunsuke , Kurahashi Hiroki , Shiroki Ryoichi
Published: February 2022

Tuberous sclerosis complex (TSC) is an autosomal dominant disease caused by loss-of-function mutations in either of two tumor suppressor genes, TSC1 and TSC2. These mutations lead to the growth of benign tumors and hamartomas in many organs, including those of the central nervous system, the skin, and the kidneys. To investigate the genotype-phenotype correlation, we performed sequence analysis of the TSC1/2 genes using next-generation sequencing. We classified 30 patients with TSC whose pathogenic variants were identified into two groups: those with mutations producing premature termination codons (PTCs) and those with missense mutations. Then, we compared the phenotypes between the two groups. Patients with a PTC were significantly more likely to manifest the major symptoms of the diagnostic criteria than those without a PTC (P = 0.035). The frequencies of subependymal nodules (P = 0.026), cortical tubers (P = 0.026), and renal cysts (P = 0.026) were significantly higher in PTC-containing variants than in cases without a PTC. When the analyses were limited to renal angiomyolipoma (AML) cases with TSC2 mutations, there was no difference in tumor size between cases with and without a PTC. However, the cases with a PTC showed a trend toward disease onset at a younger age and multiple tumors, and bilateral disease was observed in their AML lesions. TSC patients with PTC-producing mutations might potentially manifest more severe TSC phenotypes than those with missense mutations. A larger-scale study with appropriate samples deserves further investigation.
El Niño/Southern Oscillation inhibited by submesoscale ocean eddies
Authors: Wang Shengpeng , Jing Zhao , Wu Lixin , Cai Wenju , Chang Ping , Wang Hong , Geng Tao , Danabasoglu Gohkan , Chen Zhaohui , Ma Xiaohui , Gan Bolan , Yang Haiyuan
Published: February 2022

The El Niño/Southern Oscillation is characterized by irregular warm (El Niño) and cold (La Niña) events in the tropical Pacific Ocean, which have substantial global environmental and socioeconomic impacts. These events are generally attributed to the instability of basin-scale air–sea interactions in the equatorial Pacific. However, the role of sub-basin-scale processes in the El Niño/Southern Oscillation life cycle remains unknown due to the scarcity of observations and coarse resolution of climate models. Here, using a long-term high-resolution global climate simulation, we find that equatorial ocean eddies with horizontal wavelengths less than several hundred kilometres substantially inhibit the growth of La Niña and El Niño events. These submesoscale eddies are regulated by the intensity of Pacific cold-tongue temperature fronts. The eddies generate an anomalous surface cooling tendency during El Niño by inducing a reduced upward heat flux from the subsurface to the surface in the central-eastern equatorial Pacific; the opposite occurs during La Niña. This dampening effect is missing in the majority of state-of-the-art climate models. Our findings identify a pathway to resolve the long-standing overestimation of El Niño and La Niña amplitudes in climate simulations.
Simultaneous visualization of DNA loci in single cells by combinatorial multi-color iFISH
Authors: Mota Ana , Schweitzer Maud , Wernersson Erik , Crosetto Nicola , Bienko Magda
Published: February 2022

Single-molecule DNA fluorescence in situ hybridization (FISH) techniques enable studying the three-dimensional (3D) organization of the genome at the single cell level. However, there is a major unmet need for open access, high quality, curated and reproducible DNA FISH datasets. Here, we describe a dataset obtained by applying our recently developed iFISH method to simultaneously visualize 16 small (size range: 62–73 kilobases, kb) DNA loci evenly spaced on chromosome 2 in human cells, in a single round of hybridization. We show how combinatorial color coding can be used to precisely localize multiple loci in 3D within single cells, and how inter-locus distances scale inversely with chromosome contact frequencies determined by high-throughput chromosome conformation capture (Hi-C). We provide raw images and 3D coordinates for nearly 10,000 FISH dots. Our dataset provides a free resource that can facilitate studies of 3D genome organization in single cells and can be used to develop automatic FISH analysis algorithms.
Structural differences and adsorption behaviour of alkaline metals doped zinc oxide nanoparticles
Authors: Manivannan Nithyapriya , Sycheva Anna , Kristály Ferenc , Muránszky Gabor , Baumli Peter
Published: February 2022

Nanotechnology plays a vital role in all the scientific fields including environmental research due to their surface: volume ratio compared to bulk materials. Recent studies prove their effectiveness as pollutant removal and remediation practices. Zinc oxide (ZnO) nanoparticles a multifunctional material with distinct properties and their doped counterparts were widely being studied in different fields of science. However, its application in environmental waste treatment is starting to gain attention due to its low cost and high productivity. Heavy metal pollution is one of the major pollutants affecting aquatic and terrestrial life forms. Pollution in water bodies has also raised alarming concerns in the past decades. Most of the heavy metals are essential elements in trace amounts and omnipresent in the environment, causing toxicity for living organisms, for instance, nickel. In our work, we analysed the prospect of selective removal of nickel ions by different alkaline metals (K+, Rb+, and Cs+) doped zinc oxide nanoparticles fabricated by different treatment methods (as-prepared and heat-treated). We found morphological variations from flower like to rod like owing to the alkaline cations of  the dopants. In addition, the crystal structure and its different fractions presented amorphous content of the fabricated samples increased from 2 to 10 wt% with respect to the atomic radius of dopant in as-prepared samples and not present in heat-treated samples. We report, how the structure and the sample composition directly affected their adsorption behaviour towards Nickel ions in aqueous solutions based on the micro and nano zincite ratio of the ZnO particles.
Paper-based electrochemical immunosensor for label-free detection of multiple avian influenza virus antigens using flexible screen-printed carbon nanotube-polydimethylsiloxane electrodes
Authors: Lee Daesoon , Bhardwaj Jyoti , Jang Jaesung
Published: February 2022

Many studies have been conducted on measuring avian influenza viruses and their hemagglutinin (HA) antigens via electrochemical principles; most of these studies have used gold electrodes on ceramic, glass, or silicon substrates, and/or labeling for signal enhancement. Herein, we present a paper-based immunosensor for label-free measurement of multiple avian influenza virus (H5N1, H7N9, and H9N2) antigens using flexible screen-printed carbon nanotube-polydimethylsiloxane electrodes. These flexible electrodes on a paper substrate can complement the physical weakness of the paper-based sensors when wetted, without affecting flexibility. The relative standard deviation of the peak currents was 1.88% when the electrodes were repeatedly bent and unfolded twenty times with deionized water provided each cycle, showing the stability of the electrodes. For the detection of HA antigens, approximately 10-μl samples (concentration: 100 pg/ml–100 ng/ml) were needed to form the antigen–antibody complexes during 20–30 min incubation, and the immune responses were measured via differential pulse voltammetry. The limits of detections were 55.7 pg/ml (0.95 pM) for H5N1 HA, 99.6 pg/ml (1.69 pM) for H7N9 HA, and 54.0 pg/ml (0.72 pM) for H9N2 HA antigens in phosphate buffered saline, and the sensors showed good selectivity and reproducibility. Such paper-based sensors are economical, flexible, robust, and easy-to-manufacture, with the ability to detect several avian influenza viruses.