bluuebunny/crossref_metadata_2025 huggingface dataset:
Transmaterialism Ending the Psi Wars with a New Meta-Metaphysics
Authors: Hilton Andy
Published: October 2024

The term 'psi wars' refers to a conflict between those who admit and those who reject the veridicality of psi. Some sort of 'peace' with regard to psi and related topics could be beneficial, particularly as part of a paradigm shift that is arguably already upon us. Here, the area of
interest is first conceptualized as a subject–object dichotomy ranging between the poles of the 'supernormal' and 'paranatural'. Parallel to this schema, the domain and its evidential base are sketched through three contemporary investigations exemplifying laboratory types, and some
issues are raised concerning liminality, reduction, and proof. Then, on the working assumption that the basic claim for the veridicality of the supernormal-paranatural is at least reasonable, implications for metaphysics are addressed. Taking materialism as the default position, a route through
postmaterialisms to a 'transmaterialism' is outlined. The former are to accommodate psi. The latter is introduced as a pluralist approach to metaphysics for a deeper resolution of the conflict.
Contribuciones y retos de las científicas sociales en El Salvador
Authors: Trejo-Magaña Glenda Yamileth
Published: October 2024

El estudio analiza la situación de las científicas sociales en El Salvador, abordando aspectos como: compensación, estabilidad laboral, equilibrio trabajo-vida, compromiso investigativo y percepción de género. Busca atender desigualdades salariales y estabilidad laboral, exponiendo la necesidad de revisar políticas y condiciones laborales en el ámbito científico. El objetivo es evaluar estas áreas, identificar motivaciones y destacar su impacto positivo en el país. La metodología cuantitativa involucró 19 participantes de diversas universidades, con un cuestionario estructurado. Se evidencian desigualdades salariales y desafíos laborales, con estrategias para equilibrar vida y trabajo. Las científicas tienen influencia en políticas de género. Destaca su contribución en la investigación y desarrollo en El Salvador, resaltando la necesidad de afrontar desafíos críticos como equidad salarial y género para una comunidad científica más inclusiva.
Los agentes del conocimiento
Authors: Bautista Sánchez Eduardo Antonio
Published: October 2024

Este ensayo aborda el concepto de agente epistémico social como manera de caracterizar a las entidades organizativas dedicadas a la producción del conocimiento (de manera más o menos formal) como estructuras compuestas dotadas de intención e intensión, para luego utilizarlo como elemento central de un marco que integre orgánicamente otros dos conceptos: el campo científico, retomado de Bourdieu, que enmarca la actividad científica dentro de un contexto simbólico más amplio, vinculándola con fines económicos, políticos y sociales, y el de la interseccionalidad, que revela los mecanismos hegemónicos como el resultado de la interacción de múltiples sistemas de intereses y jerarquías. Se argumenta que estos tres conceptos se entrelazan de manera sistemática, evidenciando que los agentes epistémicos sociales se desenvuelven dentro de un campo científico interseccionalmente compuesto que condiciona su actividad.
Afro-descendant Atlas: Ancestral Territories and Afro-descendant Peoples' Collective Lands in Latin America and the Caribbean
Authors:   Rights and Resources Initiative,   Proceso de Comunidades Negras,   Coordenação Nacional de Articulação das Comunidades Negras Rurais Quilombolas,   Observatorio de Territorios Étnicos y Campesinos
Published: October 2024

This Atlas of the ancestral territories, rural settlements, and collectively owned lands belonging to Afro-descendant Peoples in Latin America and the Caribbean is a product of organizations, leaders, activists, and academics involved in the Afro-descendant social movement in the Americas, the Rights and Resources Initiative (RRI), the Black Communities’ Process (PCN), and the Universidad Javeriana’s Observatory for Ethnic and Peasant Territories (OTEC). The Atlas maps the territorial presence of Afro-descendant Peoples in 15 countries in Latin America and the Caribbean, the state of recognition of their territorial rights, their overlap with areas that are important for regulating and mitigating climate change, and their contributions to conservation efforts. We conceptualize Afro-descendancy as a collective agency subject with rights that extend beyond people. Afro-descendant Peoples’ territories are currently violated and threatened, their natural resources are being plundered, and their traditional production practices and ancestral knowledge are being diminished. This Atlas attempts to give an account of the conditions in which these territories are found.
Filhos em desajuste: o comportamento de anomia em novas configurações parentais
Authors: Cartaxo Maria Cristina Barros , Cartaxo Maria Stephanie Barros , Antunes Ticiana de Oliveira
Published: October 2024

O presente artigo tem por objetivo abordar a evolução histórica da instituição familiar, destacando como as novas configurações parentais podem influenciar o comportamento de anomia dos filhos. A pesquisa tem como justificativa compreender a relação existente entre as mudanças na instituição familiar e o aparecimento do comportamento de anomia dos filhos. O trabalho começa com uma visão geral das mudanças na estrutura familiar ao longo da História do Ocidente. Em seguida, investiga-se as novas formas de organização parental, e, como essas configurações desafiam os modelos tradicionais de família, e, os padrões comportamentais dos filhos. A metodologia utilizada foi de uma revisão de literatura, com entrecruzamento de informações para encontrar interlocução entre anomia, configurações familiares e estudos da psicologia, para isso foi utilizada ferramentas de Inteligência artificial, como Litmaps e Persplexity. Outro recurso utilizado para refinamento da escrita foi o uso de IA como ChatGPT e Gemini. Como conclusão, impõe-se a necessidade de estabelecimento de regras claramente comunicadas e executadas pelos grupos familiares envolvidos nos cuidados da prole, mesmo diante de uma reconfiguração familiar. A contribuição teórica e metodológica da pesquisa está em relacionar o conceito de Anomia, advindo da Sociologia para compreender o impacto psicológico nos comportamentos de desajustes dos filhos advindos de famílias que vivenciam novas configurações familiares.
Análise produtiva e econômica da inclusão de caroço de algodão na dieta de cordeiros confinados na região sudeste de Mato Grosso, Brasil
Authors: Teodoro Miller de Jesus , Almeida Poliana Fernandes de , Libera Affonso Amaral Dalla , Perez Henrique Leal , Rebouças Geovanne Ferreira
Published: October 2024

O objetivo deste trabalho foi verificar o efeito da inclusão de 20% do caroço de algodão integral na dieta de cordeiros confinados, identificando o efeito sobre o desempenho animal e a performance econômica da atividade. O experimento foi realizado no setor de ovinocultura do Instituto Federal de Educação, Ciências e Tecnologia de Mato Grosso, Campus São Vicente, o qual possui baias individuais para cordeiros de 1,5 m² de piso cimentado. Foram utilizados 16 cordeiros contemporâneos não castrados, com aproximadamente 80 dias de idade, peso corporal médio de 19,37 kg e oriundos de um rebanho cruzado comercial das raças Santa Inês e Dorper. As dietas foram isoprotéicas e a proporção volumoso:concentrado foi de 15:85. Foi utilizado o delineamento inteiramente casualizado. Os parâmetros analisados consistiram em indicadores de desempenho produtivo dos animais, características quantitativas das carcaças e indicadores econômicos de produção. As análises de variância foram realizadas adotando o PROC GLM e verificada a significância do teste F (P<0,05). A inclusão de caroço de algodão em 20% da dieta de cordeiros confinados apresentou, valor presente líquido de 22,82% superior e elevação na taxa interna de retorno de 14% quando comparado a dieta convencional. Para a análise de desempenho animal não ocorreu diferença significativa.
Contribuições de Alex Paubel Junger para o ensino de ciências e matemática: um panorama curricular integrado
Authors: Junger Alex Paubel , Araujo Manoel Messias Pereira , Oliveira Victor Inacio de , Galoni Nisflei Carvalho
Published: October 2024

Este artigo tem como objetivo avaliar as contribuições do Prof. Dr. Alex Paubel Junger, um renomado docente do Ensino Superior, pesquisador e palestrante, em relação ao Ensino de Ciências e Matemática. A pesquisa se concentrou na análise do currículo do professor, registrado na plataforma Lattes, com o propósito de categorizar e avaliar suas produções acadêmicas voltadas para essas duas áreas. Para isso, foi realizada uma análise descritiva dos artigos científicos, livros e outros trabalhos publicados por Junger, com foco específico em suas abordagens e metodologias no ensino e na pesquisa científica. Os resultados revelam um extenso e significativo quantitativo de publicações, o que evidencia o elevado impacto e a relevância das suas contribuições para o desenvolvimento do ensino de Ciências e Matemática. A análise demonstrou que Junger publicou numerosos artigos científicos, se envolveu em diversos projetos de pesquisa e atividades de extensão, que visam aprimorar a prática docente e promover inovações pedagógicas nas áreas de Ciências e Matemática. Suas contribuições incluem a elaboração de materiais didáticos, a participação em conferências e seminários, e a orientação de alunos em Programas de Pós-Graduação e formação de novos pesquisadores. Esses esforços têm influenciado diretamente o avanço do conhecimento e a melhoria das práticas educacionais nestas disciplinas, consolidando Junger como uma figura proeminente no campo da educação científica e matemática.
Peran Ma’had Al-Zaytun dalam Pengembangan Pendidikan Berdasarkan Peraturan Daerah Kabupaten Indramayu Nomor 8 Tahun 2015 dan Siyasah Dusturiyah
Authors: Umrotati Siti , Rohmah Siti Ngainnur , Sajali Munawir
Published: October 2024

Penelitian ini bertujuan untuk mengetahui peran Ma’had Al-Zaytun dalam pengembangan pendidikan berdasarkan Peraturan Daerah Kabupaten Indramayu Nomor 8 Tahun 2015 dan Siyasah Dusturiyah. Metode yang digunakan dalam penelitian ini adalah metode penelitian hukum normatif atau juga biasa disebut penelitian perpustakaan (library research). Dengan sumber data primer dan sekunder. Hasil dari penelitian ini adalah: (1) peran Ma’had Al-Zaytun dalam pengembangan pendidikan berdasarkan Peraturan Daerah Kabupaten Indramayu Nomor 8 Tahun 2015 adalah dengan mengembangkan pendidikan secara bertahap dan berkala, bermula hanya dua tingkatan yaitu Madrasah Aliyah dan Tsanawiyah, berlanjut Madrasah Ibtidaiyah, lalu Institut Agama Islam Al-Zaytun Indonesia (IAI AL-AZIS), dan terakhir PAUD, hingga sampai pada titik one pipe education system. (2) peran Ma’had Al-Zaytun dalam pengembangan pendidikan berdasarkan Siyasah Dusturiyah adalah dengan menanamkan nilai-nilai kemandirian, kebersamaan dan cinta ilmu (hubbul ilmi) yang dilandasi oleh akhlaq al-karimah dan ketaqwaan kepada Tuhan yang maha esa, serta membangun pendidikan formal maupun informal, guna mengembangkan pendidikan berkelanjutan bagi masyarakat banyak dan sesuai dengan konstitusi atau Dusturiyah yang mengacu pada prinsip-prinsip dasar dari peraturan daerah Kabupaten Indramayu.
Pemberdayaan Masyarakat Melalui Kampung Wisata Rotan Galmantro di Kabupaten Cirebon
Authors: Renita Renita , Wijaya Atika
Published: October 2024

Artikel ini menderskripkan mengenai pemberdayaan masyarakat melalui program kampung wisata di Kampung Wisata Rotan Galmantro, yang merupakan program pembangunan dengan pengembangan potensi desa dari pemerintah Kabupaten Cirebon. Program ini bertujuan meningkatkan kesejahteraan masyarakat melalui pengembangan sektor pariwisata berbasis kerajinan rotan yang menjadi kearifan local masyarakat desa. Penelitian ini menggunakan pendekatan deskrtif-kualitatif. Focus penelitian mencakup tiga proses pemberdayaan masyarakat yang meliputi enabling, empowering, dan protecting. Hasil penelitian menunjukan bahwa setiap tahap dalam proses pemberdayaan masyarakat telah memberikan implikasi positif seperti, perubahan pola pikir yang semakin menghargai budaya, meningkatkan rasa percaya diri, serta meningkatnya kesejahteraan karena mereka mulai berani mengembangkan usaha. Meski demikian, terdapat hal-hal yang perlu diperbaiki yakni dalam pengelolaan, seperti pengurusan dan promosi wisata, partisipasi masyarakat yang rendah karena adanya konflik internal dan minimnya kontribusi para pemuda dalam mempertahankan keberlanjutan program pemberdayaan sehingga menjadi hambatan pengembangan kampung wisata ini.
Peran Ma’had Al-Zaytun dalam Upaya Pengentasan Kemiskinan Perspektif Undang-Undang Nomor 13 Tahun 2011 dan Fiqh Siyasah
Authors: Hodijah Siti , Rahim Abdur , Taufiqurachman Taufiqurachman
Published: October 2024

Penelitian ini bertujuan untuk mengetahui peran Ma’had Al-Zaytun dalam upaya pengentasan kemiskinan perspektif Undang-Undang nomor 13 tahun 2011 dan Fiqh Siyasah. Metode yang digunakan dalam penelitian ini adalah metode penelitian hukum normatif atau juga biasa disebut penelitian hukum doktriner atau penelitian perpustakaan (library research). Hasil dari penelitian ini adalah: (1) peran Ma’had Al-Zaytun dalam upaya pengentasan kemiskinan perspektif Undang-Undang nomor 13 tahun 2011 adalah meningkatkan perekonomian masyarakat sekitar Ma’had Al-Zaytun, dibuktikan adanya kegiatan pada bagian-bagian dan pusat perekonomian diantaranya pertanian, peteternakan, perikanan dan koperasi guna menciptakan perekonomian yang mandiri dengan menyediakan tanah dan modal kepada masyarakat yang memerlukannya. bergerak dalam bidang usaha pertanian. sistem bagi hasil dan memberikan kesempatan kerja kepada masyarakat sekitar khususnya di Ma'had Al-Zaytun yang mengelola pertanian dan perkebunan untuk pengentasan kemiskinan berdasarkan UU No 13 Tahun 2011. (2) peran Ma’had Al-Zaytun dalam upaya pengentasan kemiskinan perspektif Fiqh Siyasah adalah sesuai dengan pemahaman fiqh siyasah maliyah (sistem politik ekonomi Islam), yang dalam hal ini program pengentasan kemiskinan yang dilakukan Ma’had Al-Zaytun adalah dengan sistem muzara'ah atau sistem bagi hasil dari pertanian, serta adanya gerakan penyaluran zakat yang disebut dengan bakti/harokah zakat dan harokah qurban kepada masyarakat yang ada disekitar Ma’had Al-Zaytun.
Penerapan Nilai-Nilai Dasar Pancasila Sila Ke 3 di Ma’had Al-Zaytun Berdasarkan Pasal 27 Undang-Undang Dasar 1945 dan Siyasah Dusturiyah
Authors: Widodo Sri , Rahim Abdur , Sajali Munawir
Published: October 2024

Penelitian ini bertujuan untuk menggali dan menganalisis bagaimana nilai-nilai persatuan Indonesia Penerapan dalam setiap kegiatan Ma’had Al-Zaytun berdasarkan Pasal 27 Undang-undang Dasar 1945 dan Siyasah Dusturiyah. Penulis menggunakan penelitian pustaka dengan pendekatan yang penulis gunakan adalah pendekatan penelitian hukum yang dilakukan secara yuridis normatif. Sumber data yang digunakan adalah Sumber data primer yaitu Pasal 27 UUD 1945, dan Buku Ilmu Hukum dalam simpul Siyasah Dusturiyah Refleksi atas teori dan praktek Hukum Tata Negara di Indonesia Karya Ali Akbar Abaib Mas Rabbani Lubis, M..H. Hasil penelitian menunjukan bahwa Penerapan sila ke-3 Pancasila, "Persatuan Indonesia," di Ma’had Al-Zaytun diwujudkan sesuai dengan Pasal 27 UUD 1945 melalui prinsip kesetaraan yang diterapkan dalam berbagai aspek kehidupan sekolah. Setiap siswa diperlakukan sama tanpa memandang latar belakang mereka, sehingga menciptakan lingkungan yang inklusif dan harmonis. Ma’had Al-Zaytun, sebagai salah satu lembaga pendidikan Islam terkemuka di Indonesia, menonjolkan pendekatan Siyasah Dusturiyah dalam semua aspek kehidupan pendidikan dan keagamaannya. Pendidikan di Ma’had Al-Zaytun juga mengajarkan nilai-nilai universal seperti toleransi, kebersamaan, dan rasa saling menghormati yang menjadi landasan kuat untuk membangun persatuan bangsa. Kontribusi Ma’had Al-Zaytun terhadap masyarakat sekitar juga tercermin dalam partisipasi aktif mereka dalam dialog antarumat beragama dan kegiatan lintas budaya.
Clinical evidence of low-calorie and ketogenic nutrological therapy before, during and after bariatric surgery: a systematic review
Authors: Salvá Marília de Andrade , Nogueira Mateus Antunes , Lopes Hugo Menezes , Alves Márcia Cavalheiro , Carvalho Ricardo de Oliveira , Cano Ana Claudia Santana , Soares Vittor Cândido , Izidorio Frederico Teixeira , Pereira Juliana da Silva , Alves Thamyres Veras
Published: October 2024

Introduction: Obesity is a multifactorial disease that causes serious comorbidities. There are more than 2.2 billion overweight and obese people in the world. Obese patients tend to be predisposed to micronutrient deficiency even before bariatric surgery, therefore, it is imperative to supplement nutrients orally, enterally, or parenterally, according to the indications of each patient. Objective: It was highlighted the importance of low-calorie and ketogenic nutritional therapy before, during, and after bariatric surgery through the systematic analysis of clinical studies. Methods: The systematic review rules of the PRISMA Platform were followed. The search was conducted from June to July 2024 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: 119 articles were found. A total of 40 articles were fully evaluated and 34 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 23 studies with a high risk of bias and 27 that did not meet GRADE and AMSTAR-2. Most studies presented homogeneity in their results, with X2=76.5%>50%. It was concluded that nutrological therapy strategies could represent a possible alternative to other methodologies, especially when it is recommended to improve patient adherence to following the prescribed diet before bariatric surgery. Weight loss induced by the ketogenic diet before bariatric surgery has beneficial effects on reducing liver volume, metabolic profile, and intra- and postoperative complications. Knowledge of the type of bariatric surgery performed and an understanding of its anatomy and physiology are useful to provide optimal care to patients, especially in nutritional complications. Nutritional deficiencies and metabolic disorders result from “malabsorption” procedures such as RYGB. Immediate administration of thiamine is essential. Dextrose should be avoided in intravenous hydration until thiamine is adequately replaced. For all bariatric patients, a protein intake of 60-70 g/d and a multivitamin with iron and vitamin B12 supplementation is recommended. Daily calcium and vitamin D supplementation is also encouraged. In addition, serum micronutrient levels should be monitored regularly and additional supplementation should be prescribed as indicated.
EMPTY THUMB; CLOSED DEGLOVING INJURY, CASE REPORT AND REVIEW OF THE LITERATURE
Authors: Alta Okyar , Zencirli Kemal , Bal Fatih
Published: October 2024

Closed degloving injuries of the thumb, resulting in a complete empty thumb, are rare and challenging to manage, particularly in pediatric patients. This case report presents a six-year-old boy who suffered a closed degloving injury of the right thumb due to pinching by a printing machine. The patient presented with mild skin changes, decreased circulation, and radiographic findings of bony structure separation from the soft tissue, resulting in a ghost finger appearance. Immediate surgical intervention was required due to poor circulation. Closed reduction was unsuccessful, necessitating open reduction via a volar Bruner incision. Intraoperatively, the bones and tendon structures were found to be completely separated from the surrounding soft tissues as a single unit, with intact bones, tendons, pulleys, and stretched but intact ulnar and radial proper digital arteries and nerves. The finger was reattached to the distal bone using a pull-out method and stabilized. Postoperatively, no wound or circulatory issues were encountered, and full interphalangeal and metacarpophalangeal joint movements were observed. This case highlights the importance of prompt recognition and appropriate management of closed degloving injuries of the thumb to prevent potential complications and improve functional outcomes in pediatric patients.
Optimal Energy Distribution in a Smart Micro-Grid Containing a Combined Electricity with Heat System Based on Fuel Cell and Energy Storage
Authors: Holari Yaser , Sanjabi Mehran , Zishan Farhad , Kamarposhti Mehrdad
Published: October 2024

Abstract-
Aim of the study: Today, electrical and thermal loads have become one of integral components of smart micro-grids, along with the combined sources of electricity and heat production.
Methods: the optimal distribution of energy in these smart micro-grids is always one of the basic challenges of managers and operators of these micro-grids. Hence, the optimal management of power generation in a residential micro-grids based on heat and electricity generation is discussed. In this hybrid system, a fuel cell is used to generate electricity and heat, and the battery is also used as a source of energy storage.
Results: In the adopted method, at each time step, according to the amount of electrical and thermal consumption, the optimal production amount of this hybrid system is used in such a way that the cost of providing the power of the smart residential micro-grids (the cost of electricity and gas consumption) is minimized. In this regard, the variable costs of electricity prices in low-load, mid-load, and peak consumption hours along with the uncertainty of production and consumption are also considered, which have been ignored in previous researches.
Conclusion: In this research, an objective function was formed first, and this objective function is composed of different parts such as the costs of fuel cells, batteries, etc. After that, the objective function is optimized using the advanced gravity search optimization algorithm in such a way that the production costs of the fuel cell hybrid system battery, electricity, and gas consumption are minimized.
Alteration of clinical parameters before mortality and prognostic outcomes of pulmonary hypertension in dogs with myxomatous mitral valve disease
Authors: Channgam Phuttipan , Sakcamduang Walasinee , Chanmongkolpanit Kittara , Kaenchan Pemika , Buayam Wasana , Janhirun Yada , Phonarknguen Rassameepen , Tansakul Mookmanee , Riengvirodkij Nattapon
Published: October 2024

Background:
Myxomatous mitral valve degeneration (MMVD) is a prevalent canine heart condition often accompanied by pulmonary hypertension (PH). Echocardiography is a valuable diagnostic tool for MMVD, but its accessibility is limited in small veterinary clinics.
Aim:
This study aimed to identify clinical parameters and biochemistry and cardiac biomarkers as prognostic indicators for cardiac mortality in MMVD dogs with and without PH.
Animals: Ninety-nine MMVD dogs and nineteen normal dogs.
Methods:
In a five-year longitudinal study, data, including clinical and laboratory measurements as well as echocardiographic parameters were collected every 6 months. Dogs were monitored until death or loss to follow-up, and the cause of death was determined when possible. Statistical analysis was performed to identify factors that predicted death.
Results:
Alterations in body condition score, total protein, fractional shortening percentage, and mean corpuscular volume were predictive of impending cardiac mortality. High blood urea nitrogen-to-creatinine ratio and heart rate and low hemoglobin levels were associated with increased risk of death. N-terminal pro-B-type natriuretic peptide was also a significant predictor of cardiac-related mortality, with higher levels indicating increased risk. Moreover, MMVD dogs with PH had a significantly lower survival rate than those with MMVD without PH. However, no significant difference in survival was observed between MMVD stage C and D with PH and MMVD stage C and D without PH groups.
Conclusion:
These findings provide valuable insights into the monitoring of MMVD progression in dogs using clinical parameters and biomarkers, especially when echocardiography cannot be performed.
Therapeutic potential of Tithonia diversifolia extract: Modulating IL-35, TNF-α, and hematology profile in streptozotocin-induced rat model
Authors: Solfaine Rondius , Hamid Iwan , Desiandura Kurnia
Published: October 2024

Background:
Diabetes mellitus is a significant global health issue with increasing prevalence worldwide.
Aim:
This study aims to investigate the potential of Tithonia diversifolia extract (TE) in lowering interleukin-35 (IL-35), tumour necrosis factor-alpha (TNF-α), and haematological profile in streptozotocin-induced rats.
Methods:
A total of 24 rats were divided into four treatment groups: control (P0), diabetic induction (P1), diabetic induction + TE (P2), and diabetic induction + quercetin (P3). Diabetes mellitus was induced by a single-dose injection of streptozotocin (60 mg/kg). TE treatment was administered orally for 7 days. On the 8th day post-treatment, all animals were euthanized, and blood samples were collected to assess inflammatory parameters, including IL-35, TNF-α, GPx, and hematological profiles. Kidney organs were fixed in 10% buffered neutral formalin for histopathological analysis. Data were analyzed using ANOVA followed by Duncan's test (p < 0.05).
Results:
Evaluation of the hematological profile revealed significant improvements in the P2 and P3 groups, with decreased leukocytes, hemoglobin, lymphocytes, and neutrophils, as well as significantly lower IL-35 and TNF-α levels observed in diabetic rats following TE treatment.
Conclusion:
TE treatment exhibited promising effects in reducing inflammatory markers and restoring hematological parameters in diabetic rats, indicating its potential as a therapeutic agent in diabetic rats.
Mutation on Theileria species in cattle in Fallujah city, west region of Iraq
Authors: Salih Dunya , Jebur Lina , Taii Noor , Ibadi Wurood
Published: October 2024

Background:
Theileriosis infection is a tick-borne disease that leads to global animal morbidity, mortality and economic losses.
Aim:
This study aimed to examine Theileriosis infection by traditional and molecular methods
Methods:
A total of 100 blood samples of local breed cows were examined by Giemsa smearing under a microscope, amplified-PCR in region 18SrRNA PCR at 600bp, and DNA sequencing analysis the genetic relationships.
Results:
The clinical signs showed that an elevated fever [40.3-41.5°C], an asymmetrical extension of superficially prescapular lymph nodes, lacrimation, icteric mucus membranes eyes, ecchymotic haemorrhages on sclera, dullness, lethargy, salivation, and ticks presence. Giemsa-stained blood smear and conventional PCR were revealed 24% and 73% for infection respectively. Phylogenetic tree was constructed with DNA sequencing analysis of accession number: OQ779946.1, OQ779947.1, OQ779949.1, OQ779952.1, OQ779953.1 and OQ779953.1, belonging to T. annulata; acc. nos.: OQ779950.1, OQ779951.1 belong to T. parva; acc. nos.: OQ779948.1, OQ779960.1 belongs to Theileria species; acc. no.: OQ779955.1, OQ779957.1, OQ779958.1 belong to T. sergenti; and OQ779956.1, OQ779959.1 belong to T. orientalis. Nucleotide substitutions of transversion and transitions occurred in 11 types containing gaps and missing are A>T; A>C; A>G; C>A; C>G; C>T; G>A; G>C; G>T; T>A; T>C for 254 positions in final dataset.
Conclusion:
This study showed theileriosis infection is highly endemic and represent a first investigation into use of molecular phylogeny to classify Theileria in Al-Fallujah City, West Region of Iraq.
In vivo toxicity study in Sprague-Dawley rats receiving different doses of Moringa oleifera extract
Authors: Kambuno Norma , Louisa Melva , Wuyung Puspita , Silaen Otto , Supali Taniawati
Published: October 2024

Background:
Protein deficiency poses a significant challenge during the growth and development of children. Moringa oleifera Lam (MO) leaves, renowned for their high protein content, present a potential solution to address amino acid imbalances in protein-deficient conditions.
Aim:
This study aimed to evaluate the toxicity of MO leaves extract in Sprague-Dawley Rats.
Methods:
Protein extraction from Moringa oleifera (MO) leaves was performed using ultrasonic-assisted extraction (UAE) with ethanol. The ethanol leaf extract of MO (EEMO) was then characterized for protein content, amino acids, minerals, phytic acid, and phytochemicals. Antioxidant activity was assessed using the DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) test, while cytotoxicity was evaluated using the MTT (3-(4,5-dimethylthiazolyl-2)-2,5 diphenyltetrazolium bromide) assay on HepG2 and MDCK cells. EEMO was tested for acute toxicity in 60 healthy male and female Sprague-Dawley rats. The rats were divided into five groups of six rats each, receiving single oral doses of 5, 50, 300, 2,000, and 5,000 mg/kg body weight (BW) of EEMO. Observations was conducted daily till day 14 before necropsy of rats. Liver and kidney tissues were harvested and preserved in 10% formalin for histopathological analysis.
Results:
The extraction process revealed a protein content of 45.5%, with phenylalanine being the predominant essential amino acid at 22.25 mg/g, and glutamic acid as the dominant non-essential amino acid at 60.03 mg/g. Potassium (1174.23 mg/100g) and selenium (149 mg/100g) were identified as the primary macro and micro minerals, respectively. The IC50 and CC50 values for antioxidant and cytotoxic activities in HepG2 and MDCK were found to be 41.04 ppm,182.66 ppm and 121.04 ppm respectively. Toxicity testing on experimental animals resulted in an LD50 value of 5,000 mg/kg BW for EEMO, indicating its relative safety upon oral administration.
Conclusion:
MO extract produced by the UAE extraction method, containing high-quality food-grade protein, showed no cytotoxic effects on HepG2 and MDCK cells and exhibited no acute toxicity in rats.
EXPOSIÇÃO INTRAUTERINA A ANTIDEPRESSIVOS vs. HIPOGLICEMIA NEONATAL: UMA REVISÃO SISTEMÁTICA
Authors: Martins Jéssica Costa , Soares Ligia dos Santos Mendes Lemes
Published: October 2024

Considerada um problema metabólico grave, a hipoglicemia neonatal pode levar ao comprometimento do neurodesenvolvimento e ao atraso no desenvolvimento motor na infância. Fatores maternos e fetais podem contribuir para a hipoglicemia neonatal como, por exemplo: diabetes mellitus materno, prematuridade, problemas de crescimento intrauterino, cardiopatia congênita e medicamentos maternos. Entre os medicamentos maternos, incluem-se os antidepressivos. No entanto, o risco de hipoglicemia em recém-nascidos de mães que recebem medicamentos antidepressivos tem sido menos frequentemente investigado em comparação com outras condições perinatais, como desconforto respiratório, necessidade de cuidados neonatais e escore de Apgar. Portanto, o objetivo da revisão atual foi avaliar sistematicamente se existe alguma conexão entre a exposição intrauterina repetida a antidepressivos e hipoglicemia neonatal em recém-nascidos com base em dados de estudos publicados recentemente. Esta revisão sistemática foi realizada conforme a metodologia Preferred Repor Ting Items for Systematic Review and Meta-analyses-PRISMA e inclui artigos nacionais e internacionais publicados em bancos de dados eletrônicos, incluindo Nature, PubMed e Biblioteca Virtual em Saúde (BVS) de janeiro de 2014 a janeiro de 2024 que abordaram a hipoglicemia neonatal e sua associação com o uso de antidepressivos na gestação. Como estratégia de busca foi utilizada a combinação de termos pré-definidos de acordo com os Descritores Ciências da Saúde (DESC), utilizando a seguinte combinação de descritores em português: hipoglicemia neonatal, antidepressivos, gestação e seus correspondentes em inglês: neonatal hypoglycemia, antidepressants, gestation. Contudo, análises revisadas recentemente indicam que as mulheres grávidas tratadas com antidepressivos têm maior probabilidade de os seus filhos desenvolverem hipoglicemia neonatal do que as mulheres grávidas que não utilizam esses medicamentos.
ОРГАНИЗАЦИОННАЯ ЭВОЛЮЦИЯ СТРОИТЕЛЬНЫХ КОМПАНИЙ СОВРЕМЕННОГО РЫНКА
Authors: Марин К.Е.
Published: October 2024

В статье рассматривается подход к преодолению проблем, связанных со снижением динамики организационной эволюции строительных предприятий и повышением эффективности управления в условиях неопределенности и непредсказуемости рыночной среды. Автор акцентирует внимание на важности ситуационного подхода и сценарного планирования для успешной адаптации к изменениям внешней среды, в статье предлагается подход к принятию управленческих решений, направленных на повышение устойчивости и конкурентоспособности строительных компаний. По результатам исследования достигнуты научные выводы, подтверждающие необходимость использования ситуационного подхода и сценарного анализа в управлении организационной эволюцией строительных компаний. Выявлена значимость анализа экзогенных и эндогенных факторов для повышения гибкости и адаптивности организационных систем. Показано, что в процессе принятия управленческих решений необходимо включать в анализ оценку экзогенных и эндогенных факторов, разрабатывать альтернативные сценарии развития для учёта возможных рисков, обеспечивать снижение управленческой реактивности, а также повышение организационной устойчивости. Внедрение данных управленческих принципов позволит строительным компаниям своевременно реагировать на изменения внешних условиях, избегать возникновения кризисных явлений, а также обеспечивать улучшение организационной динамики, что особенно актуально в условиях неопределенности и нестабильности.

The article considers an approach to overcoming the problems associated with a decrease in the dynamics of the organizational evolution of construction enterprises and an increase in management efficiency in conditions of uncertainty and unpredictability of the market environment. The author focuses on the importance of a situational approach and scenario planning for successful adaptation to changes in the external environment, the article proposes an approach to making managerial decisions aimed at increasing the sustainability and competitiveness of construction companies. Based on the results of the study, scientific conclusions have been reached confirming the need to use a situational approach and scenario analysis in managing the organizational evolution of construction companies. The importance of analyzing exogenous and endogenous factors for increasing the flexibility and adaptability of organizational systems has been revealed. It is shown that in the process of making managerial decisions, it is necessary to include an assessment of exogenous and endogenous factors in the analysis, to develop alternative development scenarios to take into account possible risks, to ensure a decrease in managerial reactivity, as well as an increase in organizational stability. The implementation of these management principles will allow construction companies to respond in a timely manner to changes in external conditions, avoid the occurrence of crisis phenomena, and also ensure the improvement of organizational dynamics, which is especially important in conditions of uncertainty and instability.
МЕТОДЫ ОЦЕНКИ ЭФФЕКТИВНОСТИ ИСПОЛЬЗОВАНИЯ ТЕХНОЛОГИЙ ИНТЕРНЕТ-КОММУНИКАЦИЙ
Authors: Баженов В.С.
Published: October 2024

Целью настоящего исследования является предложение универсальной методики измерения результатов интернет-коммуникаций. Теоретическая значимость поставленной цели обусловлена тем, что развитие интернет-коммуникаций имеет социально-психологические, культурные и экономические последствия для всего общества, в том числе и для маркетинга. Результатом исследования является предложенная универсальная методика оценки маркетинговых интернет-коммуникаций, включающая несколько этапов, а именно: определение целей маркетинговой кампании, например, повышение узнаваемости бренда, привлечение клиентов, увеличение конверсии или удержание аудитории, выбор подходящих метрик, таких как охват, вовлеченность, конверсия и удержание с целью детализировать эффективность кампании. Важными элементами являются интеграция количественных и качественных методов анализа, что позволяет не только собирать данные о поведении пользователей, но и оценивать их удовлетворенность и восприятие бренда, а также факторный анализ, который выявляет вклад каждого элемента кампании и позволяет оптимизировать маркетинговые бюджеты. Регулярная корректировка стратегии и визуализация данных обеспечивают гибкость в управлении кампаниями и более точную оценку их эффективности. Практическая значимость полученных научных результатов заключается в создании условий для более активного внедрения маркетинговых инноваций, повышения эффективности интернет-коммуникаций и конкурентоспособности компаний в цифровом пространстве.

The purpose of this study is to propose a universal methodology for measuring the results of Internet communications. The theoretical significance of the objective is due to the fact that the development of Internet communications has socio-psychological, cultural and economic implications for the whole society, including marketing. The result of the study is the proposed universal methodology for evaluating Internet marketing communications, which includes several steps, namely: defining the objectives of a marketing campaign, such as increasing brand awareness, attracting customers, increasing conversion or audience retention, selecting appropriate metrics such as reach, engagement, conversion and retention in order to detail the effectiveness of the campaign. Important elements are the integration of quantitative and qualitative analysis methods, which allows not only collecting data on user behavior but also evaluating user satisfaction and brand perception, as well as factor analysis, which reveals the contribution of each element of the campaign and allows optimizing marketing budgets. Regular strategy adjustment and data visualization provide flexibility in campaign management and a more accurate assessment of their effectiveness. The practical significance of the obtained scientific results lies in creating conditions for more active implementation of marketing innovations, increasing the effectiveness of Internet communications and the competitiveness of companies in the digital space.
SPORTS CUPPING FOR SUPRASPINATUS TENDINOSIS: A CASE STUDY
Authors: Helmy Saleh Ahmed , Hassan Shahira , Bayomy Mohamed F.F , Shaikh Tabish Ishaq , Hussein Emad Ahmed
Published: October 2024

Supraspinatus tendinosis is a common source of shoulder pain. This tendinopathy is in most cases caused by an impingement of the supraspinatus tendon on the acromion as it passes between the acromion and the humeral head. Pain, and a decrease in range of motion, strength and functionality are the main complaints that accompany this injury. Being one of the well-established techniques, Sports wet cupping therapy (WCT) was used to treat a case of Supraspinatus tendinosis in this study. This paper aims to report the improved case of supraspinatus tendinosis using the treatment with sports cupping.  We used sports cupping therapy for treatment of this patient. This case is measured and assessed by visual analogue scale (VAS), shoulder range of motion (ROM) and shoulder physical examination. Results show the VAS decreased from 10 to 1 and the patient showed nearly full shoulder range of motion in forward flexion, abduction, extension, internal rotation and external rotation. In addition, the physical examination of shoulder and MRI was improved. Sports cupping treatment with wet cupping therapy is found to be helpful to relieve pain and recover function of shoulder joint.
THE POTENTIAL OF GINGEROL ACTIVE COMPOUNDS IN ZINGIBER OFFICINALE AS ANTI-CANCER AGENTS
Authors: Layal Kamalia , Anggun H Aisyah , Salsabillah Nadya , Adenina Syarinta
Published: October 2024

Cancer is a type of chronic disease which is the main cause of death in the world with 19.3 million new cases in 2020. Current cancer treatment includes surgery, chemotherapy, radiotherapy, hormone therapy, antiangiogenesis inhibitors, stem cell therapy, and others. Long-term cancer treatment can cause other health problems, so alternative anti-cancer therapy with the fewest side effects is needed. One natural ingredient that is known to prevent and act as anti-cancer therapy is Zingiber officinale. Zingiber officinale contains gingerol which functions as an anti-oxidant, anti-inflammatory, anti-bacterial, anti-cancer, anti-tumor and anti-mutagenic. The anticancer effects of gingerol are known to be effective in cancers of the liver, stomach, mouth, prostate, breast and ovaries. This literature aims to delve deeper into the role of gingerol as an anti-cancer compound. The strategy employed in the article search involved using electronic databases such as Google Scholar and PubMed. Keywords utilized included "cancer," "red ginger," "gingerol," "Zingiber officinale," and "anticancer." The articles selected were those published within the last 10 years. The study results indicate that gingerol is beneficial in oral, breast, lung, colorectal, cervical, and prostate cancers. The mechanism of action of gingerol involves pathways such as the PI3K/AKT, JAK/STAT, apoptosis, and ROS proliferation pathways. Gingerol is known to be effective as an anti-cancer agent and has the potential to become one of the alternative anti-cancer treatments.
LITERATURE REVIEW THE ROLE OF ACUPUNCTURE IN THE MANAGEMENT OF PERIPHERAL NEUROPATHY
Authors: Rosalyn Elisha , Septadina Indri Seta
Published: October 2024

Peripheral neuropathy (PN) is a condition characterized by damage to the peripheral nervous system, resulting in symptoms such as pain, numbness, and weakness in the hands and feet. The most common causes include diabetes, thyroid disorders, vitamin B12 deficiency, alcohol abuse, chemotherapy, and human immunodeficiency virus (HIV) infection. Despite the availability of various treatments, neurological disorders remain a significant therapeutic challenge. The therapeutic effects of acupuncture are attributed to several mechanisms, including stimulation of nerve fibers, restoration of blood flow, release of neurotransmitters and hormones, modulation of the autonomic nervous system, anti-inflammatory effects, and increased neuroplasticity. These mechanisms collectively contribute to the relief of symptoms associated with peripheral neuropathy. Evidence suggests that acupuncture is beneficial in treating peripheral neuropathy. Studies have shown that acupuncture can improve nerve conduction study parameters in sensory and motor nerves, reduce neuropathic pain, and improve overall nerve function. Certain acupuncture points such as ST-36, GB-34, SP-3, SP-8, and BI-56 have been identified as particularly effective in managing symptoms of peripheral neuropathy. Although more rigorous studies are needed to fully characterize the effects of acupuncture on peripheral neuropathy, the available evidence supports its use as a complementary therapy. Standardized acupuncture protocols that combine anatomical correlation with peripheral nerves and traditional approaches to neuropathic pain management appear to be effective. Further studies with larger sample sizes and randomized comparisons to sham acupuncture will help establish acupuncture as a guideline for treating peripheral neuropathy. This review outlines the potential of acupuncture as a complementary therapy in the management of peripheral neuropathy.
Poliomielitis: un viaje a través de la historia
Authors: Martínez Vásquez Jorge , Porras Umaña Tatiana
Published: October 2024

Resumen La poliomielitis es una enfermedad causada por un virus de la familia del enterovirus que provoca un alto porcentaje de parálisis flácida. Este virus ingresa al ser humano por medio de la nariz y produce infección en la mucosa orofaríngea y gastrointestinal. Entre los años 1955 y 1961, se desarrolló la vacuna para combatirla, la cual se empezó a distribuir mundialmente, sin embargo, no se logró evitar diversos brotes a lo largo del tiempo. El último reportado fue en el 2018 en el continente africano con treinta y tres casos.
Revisión de trastornos pigmentarios cutáneos
Authors: Arias Argüello Andrea
Published: October 2024

Resumen La variación en la piel y el color del cabello es el aspecto más notable de la variabilidad humana. La condición de la piel indudablemente atisbará la existencia de salud y belleza, por lo cual el conocimiento de su homeostasis así como de su ausencia permite desarrollar un enfoque apto no solo para el tratamiento de enfermedades cutáneas sino también para cuidar adecuadamente de esta. Este artículo inicia con la descripción de la melanogénesis así como de la influencia de los factores genéticos y ambientales que permitirá al lector comprender mejor el origen de los trastornos de la pigmentación cutánea más frecuentes, tanto por exceso (hiperpigmentación) como por defecto (hipopigmentación). Aunque en su mayoría, son trastornos benignos, algunos resultan en preocupaciones cosméticas o psicológicas para el paciente, que requieren evaluación y tratamiento. El diagnóstico adecuado le permite al médico facilitar el tratamiento apropiado, brindarle tranquilidad o iniciar una derivación oportuna.
Enfermedad por Coronavirus: ¿Qué sabemos hasta hoy?
Authors: Arias Argüello Andrea
Published: October 2024

Resumen Si bien en el pasado los coronavirus humanos fueron catalogados como causantes de patologías de características leves, por tercera ocasión, durante el siglo XXI, un coronavirus zoonótico ha cruzado especies para infectar a la población humana. Este último virus, denominado inicialmente coronavirus de Wuhan, 2019 Novel Coronavirus n2019 CoV y, actualmente, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) se identificó por primera vez a finales del mes de diciembre del 2019 en la República Popular de China, previo al inicio del Año Nuevo Lunar Chino, el evento anual de viajes en masa más grande del mundo. El alcance y el efecto final de este virus no está claro en la actualidad, ya que la situación está evolucionando rápidamente. Las otras dos cepas: el síndrome respiratorio agudo severo asociado a coronavirus (SARS-CoV) y el síndrome respiratorio del Medio Oriente por coronavirus (MERS-CoV), son también de origen zoonótico y se han relacionado con enfermedades en ocasiones asociadas a mortalidad. El SARS-CoV fue el agente causal de los brotes de síndrome respiratorio agudo severo en 2002 y 2003 en la provincia de Guangdong, China. MERS-CoV fue el patógeno responsable de brotes de enfermedades respiratorias graves en 2012 en el Medio Oriente. Este artículo pretende describir las especies de la familia Coronaviridae que afectan a los humanos, específicamente SARS y MERS; se enfatiza en el SARSCoV- 2, sus características y las lecciones importantes de la pandemia por coronavirus 2019 (COVID-19).
The Potential of Near-infrared Spectroscopy to Predict Soil Nutrient Contents Based on Soil Color
Authors: Khammao Piyamas , Rattanapichai Wutthida , Pitakdantham Roongroj , Kasemsap Poonpipope , Sajjaphan Kannika
Published: October 2024

Near-infrared spectroscopy (NIRs) analysis in laboratory-based settings has the potential to predict soil elements. The aim was to explore the effects of soil color on the prediction of total nitrogen (N), available phosphorus (P), and extractable potassium (K) contents using near-infrared spectroscopy in the range of 1000–2500 nm. Two hundred forty soil samples were collected from a paddy field in northeast Thailand. We divided the soil samples based on soil color using the Munsell color chart to construct a model to predict nutrient contents based on soil color. Regression models for soil nutrient contents were developed using partial least squares regression (PLSR) models. The best predictions were obtained for N (R² = 0.87, RMSE = 0.131), P (R² = 0.87, RMSE = 7.713) and K (R² = 0.77, RMSE = 14.944). This research demonstrates the viability of employing Near-Infrared spectroscopy (NIRs) as a reasonable method for predicting soil nutrient contents.