bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnosis dan Tatalaksana Infark Miokard Akut Ventrikel Kanan
Authors: Kurnia Andy
Published: July 2022

Infark miokard akut ventrikel kanan (IMA-VKa) merupakan salah satu sindrom koroner akut (SKA) memiliki angka kejadian cukup tinggi. Perlu diagnosis serta tatalaksana secara cepat, tepat, dan akurat guna mengurangi angka morbiditas dan mortalitas.

Right ventricle acute myocardial infarction is an acute coronary syndrome with high prevalance. Prompt and accurate diagnosis and management is needed to reduce morbodity and mortality.
Efikasi Suplementasi Vitamin D terhadap Indeks Glikemik pada Diabetes Melitus Gestasional
Authors: Safitri Yolanda , Novita Rachma , Louisa Melva
Published: July 2022

Beberapa studi efikasi suplementasi vitamin D pada diabetes melitus gestasional hasilnya masih bertentangan. Laporan kasus berbasis bukti ini bertujuan untuk konfirmasi efikasi suplementasi vitamin D terhadap kontrol glikemik pada wanita hamil dengan diabetes melitus gestasional dan hipovitaminosis D. Pencarian artikel komprehensif melalui PubMed dan Scopus. Studi yang dipilih adalah studi dengan desain randomized controlled trial atau systematic review pada wanita hamil dengan diabetes melitus gestasional dan hipovitaminosis D membandingkan terapi standar obat anti diabetes (OAD) dengan obat terapi standar dan suplementasi vitamin D. Telaah kritis sesuai perangkat dari Center for Evidence Based Medicine (CEBM). Diperoleh 3 studi systematic review yang memenuhi kriteria eligibilitas. Dua studi menunjukkan perbedaan kadar glukosa darah puasa dan HbA1C yang bermakna secara statistik dan klinis pada kelompok yang mendapat suplementasi vitamin D dibandingkan kelompok kontrol. Satu studi hasilnya tidak bermakna.

Results of recent studies on the use of vitamin D supplementation in gestational diabetes mellitus were conflicting. This evidence-based case report aimed to confirm the efficacy of vitamin D supplementation on glycemic control in pregnant women with gestational diabetes mellitus and hypovitaminosis D. A comprehensive search for articles in PubMed and Scopus included randomized controlled trial or systematic reviews in gestational diabetes mellitus and hypovitaminosis D comparing standard anti-diabetic drug therapy (OAD) with standard therapeutic drugs and vitamin D supplementation. Critical appraisals were done using the tools from Center for Evidence Based Medicine (CEBM). Three systematic reviews met the eligibility criteria. Two studies showed statistically and clinically significant differences in fasting blood glucose and HbA1C level in vitamin D supplementation group compared to the control group, while the result of the third study was not significant.

 
Sistem Skoring Alberta Stroke Program Early CT Score untuk Evaluasi Kasus Stroke Iskemik
Authors: Michael Lie
Published: July 2022

Sistem skoring Alberta Stroke Program Early CT Score (ASPECTS) merupakan alat skoring semi – kuantitatif sederhana untuk mengevaluasi gambaran iskemi akut pada CT scan non kontras atau MRI. Pada awal publikasinya, sistem skoring ini dianggap dapat memprediksi outcome fungsional dan kejadian transformasi perdarahan pada pasien yang menjalani trombolisis intravena dengan alteplase. Namun rekomendasi terbaru tidak lagi merekomendasikannya. Data efektivitas trombektomi mekanik pada populasi dengan nilai ASPECTS ≤ 5 belum cukup. Tulisan ini membahas cara menilai, kegunaan serta implikasi sistem skoring ASPECTS terhadap tatalaksana pasien dengan stroke iskemi akut

Alberta Stroke Program Early CT Score (ASPECTS) is a simple semi-quantitative scoring system to evaluate the noncontrast CT Scan or MRI imaging of acute ischemic lesion. Originally, the scoring system was considered able to predict the functional outcome and hemorrhagic transformation in patient undergoing intravenous thrombolysis with alteplase. However, the latest guideline does not recommend ASPECTS to determine the eligibility of patient undergoing alteplase therapy. Data regarding the efficacy of MT in patient with ASPECTS ≤ 5 is scarce and is still a subject of debate. This article will discuss the evaluation and the implication of ASPECTS scoring system in the management of acute ischemic stroke.
Nevus Melanositik Kongenital Raksasa dan Kelainan Kongenital Ekstremitas pada Bayi Baru Lahir
Authors: Antonius Cayadi Sidarta , Wijayadi Linda Julianti
Published: July 2022

Nevus Melanositik sejak lahir ditemukan pada satu persen anak di dunia dengan ukuran bervariasi. Salah satu varian nevus melanositik yang sangat jarang, berukuran sangat besar, yakni Nevus Melanositik Kongenital Raksasa (NMKR). Pada tulisan ini dilaporkan kasus NMKR disertai kelainan kongenital ekstremitas. Seorang bayi perempuan lahir di puskesmas dengan partus spontan dirujuk ke IGD, 3-4 jam setelah lahir. Terdapat bercak hitam di area perut, punggung, dan paha. Didapatkan juga perbedaan panjang tungkai, serta hanya ada 3 jari di kaki kanan. Tatalaksana diberi pelembap. Kasus ini jarang; diperlukan konsultasi dan observasi teratur untuk meningkatkan dan memperpanjang harapan hidup.

Melanocytic Nevus since birth is found in one percent of children in the world with variable severity. One of the rare variant is very large melanocytic nevus variant called Giant Congenital Melanocytic Nevus (GCMN). This paper reported a case of GCNM accompanied with congenital abnormalities of the extremities. A baby girl who was born spontaneously in a clinic, was referred to the emergency department about 3-4 hours after her birth. The abnormalities were black spots in the abdominal area, back, and thighs. The patient also had different length of legs differences with only 3 toes on right foot. The patient was given moisturizer. GCMN case accompanied with congenital limb abnormalities is rare; regular consultation and observation are required to improve and prolong survival.
Peran Probiotik sebagai Pencegahan Dermatitis Atopi
Authors: Sie Shun Ling Michael , Kurniawan Marsha , - Brigitta
Published: July 2022

Dermatitis atopi (DA) merupakan radang kulit yang bersifat kronik dan residif. DA umumnya muncul pertama kali pada tahun pertama kehidupan. Penyebab DA multifaktorial disertai riwayat atopi lain pada penderita maupun keluarga. Terapi DA simptomatik, sehingga sering gagal dan berdampak pada kualitas hidup pasien maupun keluarganya. Penelitian terbaru menunjukkan bahwa probiotik terutama strain bakteri campuran, sangat bermanfaat sebagai pengobatan dan pencegahan DA.

Atopic dermatitis (AD) is a chronic and recidive inflammatory skin disease. AD commonly appear in the first year of life. Cause of AD is multifactorial with past or familial history of other atopy. AD therapy is symptomatic, resulting in frequent failure and impact on the quality of life of patients and their families. Recent research shows that probiotics, especially mixed bacterial strains is very useful as a treatment and prevention of AD.
Modalitas CT-Scan Toraks sebagai Pemeriksaan Penunjang pada COVID-19
Authors: Suryamin Ricky
Published: July 2022

Coronavirus disease 2019 (COVID-19) adalah suatu penyakit infeksius yang disebabkan oleh spesies coronavirus, yaitu severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Kasus pertama diketahui di Wuhan, China pada Desember 2019, sebelum akhirnya menyebar ke seluruh dunia dan menjadi pandemi pada Maret 2020. Radiologi memiliki peranan penting dalam skrining dan diagnosis pneumonia pada umumnya, termasuk pneumonia COVID-19. Pemeriksaan radiologi CT-Scan toraks memiliki sensitivitas 71%; ada beberapa tanda khas dan bisa dibedakan dari penyakit paru lain. Pemeriksaan CT-Scan dapat berguna saat menunggu diagnosis laboratorium reverse transcription polymerase chain reaction (RT-PCR).

Coronavirus disease 2019 is an infectious disease caused by coronavirus species - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was reported in Wuhan, China in December 2019, and became pandemic in March 2020. Radiology has an important role in screening and diagnosis of general pneumonia, including COVID-19 pneumonia. Thorax CT-scan examination has 71% sensitivity because several disease mimic COVID-19; but some specific appearance can differentiate with other lung diseases. CT-Scan may be useful while waiting for reverse transcription polymerase chain reaction (RT-PCR) result for definite diagnosis of COVID-19 pneumonia.
Diagnosis dan Tatalaksana Kriptorkhismus
Authors: Irsyada Yusuf Amry
Published: July 2022

Kriptorkhismus merupakan kelainan genital paling sering pada bayi laki-laki. Faktor risikonya adalah prematuritas, riwayat keluarga, berat bayi baru lahir rendah, riwayat merokok selama kehamilan, penggunaan obat analgesik, dan pemberian hormon estrogen selama kehamilan. Diagnosis dengan pemeriksaan fisik yang baik penting untuk deteksi dini. Kriptorkhismus umumnya, dapat turun spontan ke skrotum dalam enam bulan pertama kehidupan. Tatalaksana pembedahan masih menjadi pilihan dengan angka kesuksesan lebih tinggi dibandingkan terapi hormonal yang saat ini tidak lagi direkomendasikan. Tatalaksana awal kriptorkhismus dapat menurunkan risiko penurunan fertilitas dan risiko keganasan testis.

Cryptorchidism is the most common genital malformation in boys. Risk factors are prematurity, family history, low birth weight, history of smoking during pregnancy, maternal use of analgesics, and exposure to high level estrogen during pregnancy. Proper physical examination contributes greatly to early detection. Most cryptorchidism can descend spontaneously into the scrotum without any medical interventions prior to six months. Surgical intervention remains the treatment of choice with a success rate significantly higher than hormonal therapy, which is no longer recommended. Early treatment can reduce risk of decreased fertility and testicular malignancy.
Pilihan Tatalaksana Penyakit Perlemakan Hati Non-Alkohol (Non-Alcoholic Fatty Liver Disease/ NAFLD)
Authors: Imanuel Setiawan Stefanus , Kurniawan Juferdy
Published: July 2022

Penyakit perlemakan hati non-alkohol (Non-alcoholic fatty liver disease/ NAFLD) merupakan kondisi adanya steatosis hepatik, inflamasi, dan kerusakan hepatosit (ballooning degeneration). NAFLD tidak hanya dianggap penyakit hati primer, tetapi juga merupakan bagian dari sindrom metabolik atau kondisi resistensi insulin dan penyakit terkait gaya hidup seperti diabetes, dislipidemia, dan hipertensi. Strategi tatalaksana NAFLD dimulai dari modifikasi gaya hidup, dapat dilanjutkan dengan terapi komponen sindrom metabolik, farmakoterapi, hingga penatalaksanaan sirosis.

Non-alcoholic fatty liver disease refers to a steatosis in liver, associated with inflammation and destruction of hepatocyte (ballooning degeneration). NAFLD is considered as primary liver disease, but also as a component of metabolic syndrome related to insulin resistance and other life-style-related diseases i.e diabetes mellitus, dyslipidemia, and hypertension. Strategies in NAFLD management start with life-style modification, continued with pharmacological approaches targeting metabolic syndrome and complications related to cirrhosis.
Capital Structure Analysis in Healthcare Issuers in the DES Category for 2017-2019
Authors: Riyandi Taufik , Riyanto Setyo
Published: July 2022

There is an increasing trend of sustainable healthy lifestyles and strong industrial potential amid a pandemic. To seize this opportunity, health companies need to increase their production capacity, and ultimately the company needs capital for its operations. Thus, it is necessary to analyze the optimal capital structure to reduce so that the company can maximize its value of the company. This study aims to analyze the company's cost of capital and analyze the optimal capital structure of the company in the pharmaceutical industry on the Sharia Stock List (DES), which is listed on the Indonesia Stock Exchange (IDX) for 2017-2019 period. The analysis was carried out by calculating the WACC, then comparing the average industrial WACC with the average value of the pharmaceutical industry companies so that they could analyze the capital structure optimally for each issuer. Calculation using Microsoft Excel 2016. The average industrial issuer was dominated by the capital structure originating from equity. In addition, the calculation of the industrial average WACC and the average value of industrial companies is 8.00% and Rp. 374,302,- (in Millions of Rupiah) where KLBF is a pharmaceutical issuer that has an optimal capital structure, namely WACC below the industry average and company value above the industry average. There is company management that is more careful and careful in determining the company's capital structure, even for working capital and or for investment, so that an optimal combination is achieved and can increase company value and reduce company risk.
Health Problems by Alcoholic Beverages in village Ukhalgaon, Taluka Shrigonda, District Ahmednagar, Maharashtra, India.
Authors: Sirsat Premchand Bhimrao , Chandan Supriya , Dhongde Pratiksha , Bhamare Amruta , Kadam Sonali Santosh , Anarse Sujit
Published: July 2022

Alcoholism is commonly found in many parts of the world. Excessive consumption of alcoholic beverages adversely affects human health, and social and commercial status and disturbs mental health. Such problems are needed to be explored and analyzed for protecting societal balance and integrity. In the present article, we surveyed health problems of villagers from Ukhalgaon, Taluka Shrigonda, District Ahmednagar, Maharashtra state of India owing to alcoholic beverages and reported that its excessive consumption resulted in heavy losses to life and social welfare.
Aprendizaje autodirigido en procesos de trabajo colaborativo en educación superior
Authors: Hernández-Sellés Núria
Published: July 2022

El aprendizaje autodirigido implica la adopción de un rol activo por parte de los estudiantes, que autorregulan su adquisición de conocimientos en procesos que abarcan la cognición, la metacognición y la motivación. El presente estudio analiza estas tres dimensiones del aprendizaje autodirigido en un proceso de trabajo colaborativo mediado por las tecnologías en el ámbito de la educación superior. En este trabajo se incluyen los resultados de una investigación cualitativa en base a un estudio de caso único en el que participan 32 alumnos. Se analiza información de distintas fuentes: los procesos de interacción grupal en foros, entrevistas y un grupo de discusión. Los resultados reflejan que los universitarios valoran las oportunidades que presenta el aprendizaje colaborativo, que la autonomía del grupo puede promover un intercambio cognitivo de alto nivel y que este está sustentado por la motivación. También se evidencia que los roles docentes se multiplican en los procesos de aprendizaje autodirigido.
Desarrollo profesional de docentes universitarios en línea: un análisis desde las ecologías de aprendizaje
Authors: Cabrera Lanzo Nati , Guàrdia Ortiz Lourdes , Sangrà Albert
Published: July 2022

La formación y el desarrollo profesional docente son los pilares sobre los que descansa la calidad pedagógica en la educación superior. La pandemia ha acelerado el impulso de la educación en línea y ha puesto de manifiesto la importancia de la formación y la actualización del profesorado que ejerce su docencia en dicha modalidad. Este artículo presenta un estudio cualitativo para determinar cuáles son los mecanismos habituales de actualización del profesorado universitario que ejerce su labor en modelos educativos virtuales. La metodología de investigación se ha basado en 12 entrevistas en profundidad a 6 enseñantes universitarios en línea, estructuradas a partir del marco de análisis de las ecologías de aprendizaje. Los resultados indican que el profesorado que trabaja a través de Internet tiende a optar por fórmulas de autoaprendizaje dirigido, priorizando mecanismos de formación no formal, de intercambio y participación en comunidades de prácticas entre iguales y de consumo de recursos digitales de referencia disponibles en la red. El concepto de ecologías de aprendizaje aplicado al desarrollo profesional y a la actualización del profesorado universitario en línea se ha demostrado como un mecanismo útil para su análisis.
Pattern of Blood Donation and Transfusion Transmissible Infections in a Hospital-Based Blood Transfusion Service in Lagos, Nigeria
Authors: Ogbenna A , Adewoyin S A , Famuyiwa C O , Oyewole K M , Oyedeji O A , Akanmu A S
Published: July 2022

Background: Blood transfusion therapy remains a mainstay in the care of many tropical diseases. Blood supply in sub-Saharan Africa (SSA) including Nigeria is still a challenge in terms of perennial blood shortages and transfusion transmissible infections (TTI). This study aimed to describe blood donation patterns and compare the rates of TTIs among types of blood donors seen at LUTH.

Study method: A 6-year retrospective review of data on donor types and pattern of TTIs at LUTH transfusion service. TTI rates and odd ratios (OR) of TTI positivity amongst VNRD versus FRD were computed at 95% confidence intervals. Proportion of TTI sero-positivity was also compared between the VNRD and FRD groups.

Results: A total of 53,319 blood donors were observed over the study period, with average of 8886.5 donors per year. VNRDs accounted for 12.3% (6533/53,319), while FRDs accounted for 87.7% (46,789/53,319) of all donors. The proportion of VNRDs ranged from 5.1% to 20.8%. The overall prevalence of TTIs over the 6-year period for all donors was 1.34% for HIV, 5.79% for HBV, 2.23% for HCV and 0.88% for syphilis. Sero-positivity rates for HIV, HBV, HCV, and syphilis was statistically significantly lower among VNRD compared to FRDs.

Conclusion: There exists a lot of room for improvement in our blood donation practices to improve blood stock and transfusion safety. A more aggressive strategic effort needs to be directed towards achieving a target of 100% voluntary blood donor base through partnerships, advocacy, more financing and resource allocation, and other proven initiatives.

Keywords: Nigeria; Transfusion; Transfusion transmitted infections; blood donors.
Epidemiologic Characteristics, Clinical Features and Outcomes of COVID 19: Patients Admitted at the Asokoro District Hospital Isolation and Treatment Center, Abuja, North Central Nigeria
Authors: Onyegbutulem H C , Dogo D , Nnabuchi C V , Aghahowa M E , Alu F E , Afiomah E U , Atanda O D , Nwankwo C G , Ani-Osheku I , Olatise O O , Abolade B O , Akerele I O , Henry-Onyegbutulem P I
Published: July 2022

Background: The COVID -19 pandemic spread rapidly across the globe, making a land-fall on the Nigerian geo-space in early 2020. Key presenting features were; fever, dry cough, fatigue, myalgia, headache, sore-throat, abdominal pain, diarrhea, dyspnoea amongst others, with a clinical spectrum ranging from mild through severe forms. Aside infection control and supportive care, there was no specific therapy until trials with Remdesivir. Studies have described limited epidemiological findings, presentations and outcomes of COVID patients in Nigeria and elsewhere, but not for the Federal Capital Territory, (FCT) specifically Abuja, the Nation's capital city and the second epicenter of the pandemic in Nigeria. The objective of this study therefore, was to describe the Clinical and demographic characteristics of the patients admitted at the Asokoro District Hospital (ADH), Abuja.

Methods: Retrospective study that used records of patients admitted, between April and September 2020. Data include; Socio-demographics, medical history, exposure, residential area, co-morbidities, symptoms, signs, treatment measures, duration of hospital stay and outcomes.

Results: 270 patients were enrolled for this study. 170(63%) males and 100(37%) females. Mean age was 40.03+13.5years. Forty-one(15.2%) had travel history while 99(36.7%) had contact with confirmed cases. Majority of the patients were married(63.33%), and had tertiary education(74.82%). Commonest symptoms were cough(43.33%), fever(36.67%), headaches(32.22%) and fatigue(31.48%). The duration of stay at the ADH ranged from 2 hours to 28 days.

Conclusion: Our patients were young, mainly of the upper class, educated people with mild to severe disease. There was one death, a case with multiple comorbid factors.

Keywords: Abuja-Nigeria; COVID patients; Socio-demographics; clinical features; outcomes.
The Rise of Tramadol Abuse as Omicron Variant Plateaus
Authors: Erhabor
Published: July 2022

The Rise of Tramadol Abuse as Omicron Variant Plateaus
Prevalence of Needle Stick and Sharps Injury and Hepatitis B Vaccination among Healthcare Workers in a South-East Nigerian Tertiary Hospital
Authors: Onubogu
Published: July 2022

Background: Daily, HCWs are exposed to needle stick and sharps injury (NSSI) and associated risk of life-threatening infections.

Aim: A cross-sectional study was conducted to determine the prevalence of NSSI and HBV vaccination among 341 HCWs at NAUTH, Nnewi.

Methods: Data was collected using a self-administered. questionnaire and interview of key staff.

Results: The mean age of participants was 33.4±11.9 years while male: female ratio was 1:1.7. Prevalence of NSSI in the preceding 12 months was 25.5% with doctors (43.0% [34/79]), laboratory scientists (27.5%[14/51]) and nurses (21.8%[17/78]) leading (p=0.014). Noncompliance with standard precaution (SP) and non-display of relevant SP SOPs in prominent places were significantly associated with NSSI (p=0.001). Among those exposed to NSSI, only 33.7% (28/83) consulted a doctor, while 16.9%(14/83) took post-exposure prophylaxis. Two-third (68.8% [190/276]) of respondents correctly cited HBV/HCV as vaccine-preventable blood-borne healthcare-associated infection (HAI) while half (50.9% [161/316]) had received HBV vaccination. Profession (p=0.018), display of SOPs in prominent places (p=0.015), ability to cite HBV/HCV as vaccine-preventable blood-borne HAI (p=0.001), and compliance with SP (p<0.001) were significantly associated with HBV vaccination. Unit heads' responses implied lack of written policy on HBV vaccination, adequate training on NSSI prevention, and HBV vaccination support.

Conclusion: Among HCWs, NSSI is high but under-reported while HBV vaccination rate is unimpressive. Profession, display of relevant SOPs, and compliance with SP positively affected both NSSI occurrence and HBV vaccination while knowledge about vaccine-preventable blood-borne HAI also influence HBV vaccination status. Written policies on HBV vaccination and NSSI prevention/ management, their communication and enforcement among HCWs, adequate training/retraining, display of SOPs in prominent places, and free HBV vaccination are recommended

Authors

C U Onubogu 1, E I Nwaneli 1, C G Chigbo 2, M C Egbuniwe 3, R O Egeonu 4, S N Chukwurah 5, N P Maduekwe 6, I Onyeyili 6, C P Umobi 3, O F Emelumadu 7
Correlative Ultrasound Evaluation of Anterior Abdominal Wall Subcutaneous Tissue Thickness in Type 2 Diabetic and Non-Diabetic Adults
Authors: Adeyekun
Published: July 2022

Background: Subcutaneous fat accumulation complicating diabetes mellitus (DM) has long been recognised, even as its clinical significance remains controversial. Ultrasound is safe and accurate in assessing soft tissue dimensions. Reports on ultrasound evaluation of anterior abdominal wall subcutaneous fat in diabetic and apparently healthy normoglycaemic subjects are scanty in the Nigerian environment.

Aims and objectives: To sonographically assess and compare the mean anterior abdominal wall subcutaneous tissue thickness (AAST) in adult diabetic subjects and apparently healthy, normoglycaemic subjects and correlate the values with age, gender, body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) and glycated hemoglobin (Hb1c).

Materials and methods: The AAST in 150 adult diabetic subjects and equal numbers of age, and sex matched apparently healthy individuals was assessed with a SONOACE X4 ultrasound scanner. (Medison Inc, SOUTH KOREA), using a l inear array transducer of frequency 7. 5MHz10MHz.Measurements were taken in the midline at two points; 2cm above and below the umbilicus. Anthropometric parameters such as BMI, WC, WHR, were recorded.

Results: Adult diabetic subjects had significantly higher AAST values, compared to age and BMI matched male and female apparently healthy controls respectively. (2.7±0.9cm vs 2.2 ± 0.9cm (below the umbilicus; p=0.001), and 2.1 ± 0.8cm vs 1.6 ± 0.8cm (above the umbilicus; p = 0.001). Below the umbilicus, AAST correlated positively with WHR, BM1 and disease duration among diabetic patients.

Conclusion: AAST is significantly increased in diabetic subjects compared to controls, and can be a useful guide in the management of obesity in these patients. There is correlation of AAST below the umbilicus with BMI and waist circumference.

Author

A A Adeyekun 1, J P Okojie 1, M M Abubakar 1, E E Efe-Aluta 1
Acute Leukaemias in Bauchi State, Northeastern Nigeria: Pattern of Presentations and Clinical Entities
Authors: Dachi
Published: July 2022

Background: Acute leukaemias are very aggressive diseases that run a rapidly fatal course if not promptly diagnosed and appropriately treated. The clinical presentations range from bone marrow failure such as anaemia, neutropenia or thrombocytopenia to features of organ infiltrations such as lymphadenopathy, splenomegaly, etc, but presentations may be non-specific. Misdiagnosis is very common with delay in diagnosis and prompt treatment being the causes of high morbidity and mortality in acute leukaemias. This study aims to determine the pattern of presentation and various clinical entities of acute leukaemias in Bauchi State, North-Eastern Nigeria.

Subjects, materials and methods: This was a three year retrospective study in which records of cases of acute leukaemias diagnosed in the Haematology Department of Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH) Bauchi from the bone marrow aspiration cytology register from 1st January, 2018 to 31st December, 2020 were collected. Data on socio-demographic characteristics of the patients that include age, gender, diagnosis as well as subtypes of some of the malignancies diagnosed were also collated. The collated data were analyzed using SPSS Version 20.0. A p-value of < 0.05 was considered significant.

Results: Twenty-nine cases of acute leukaemias were diagnosed during the period under review. Majority of cases had acute lymphoblastic leukaemia (ALL) 19/29 (65.5%) while acute myeloid leukaemia (AML) was seen in 10/29 (34.5%). The mean ± SD age of the patients was 22.2±9.2 years with a range 6 months to 60 years. Males constituted 75.9% (22/29) of the cases of acute leukaemias diagnosed. The male to female ratios for AML and ALL were 2:1 and 2.6:1 respectively. The mean±SD ages for AML and ALL were 27±9.2years and 17.3±11.3 years respectively. The most common form of presentation of acute leukaemia in this study is recurrent anaemia necessitating blood transfusion while proptosis and epistaxis were the least forms of presentation.

Conclusion: Acute lymphoblastic leukaemia is the commonest form of acute leukaemias while recurrent anaemia is the commonest form of clinical presentations in our setting. Early referral of patients with clinical features suggestive of acute leukaemias is recommended.

Author

R A Dachi 1, F G Mustapha 1, M Mahdi 1, H Abbas 2
Correlates of Depression among Elderly Patients Attending the General Out-Patient Department of a Tertiary Hospital in Northwestern Nigeria
Authors: Damagum
Published: July 2022

Background: Depression is a common mental health problem in the geriatric population associated with significant morbidity (including decreased physical, cognitive and social functioning) and mortality. Although patients differ in their presentations, certain social and demographic characteristics are common to the elderly population with depression. It is hoped that identifying these patients based on their sociodemographic characteristics will help reduce the difficulties in diagnosis.

Objective: The objective of this study is to determine the risk factors for depressive illness among elderly patients attending the GOPD of AKTH.

Methods: This cross-sectional questionnaire-based study involved 392 elderly patients systematically selected from Family Medicine Clinic attendees in Kano, Nigeria. Data collected included sociodemographic and clinical characteristics. Geriatric Depression Scale was used to screen for depression. Chi-square test and logistic regression analysis were used to determine the association between categorical variables and predictors of depression among participants, respectively.

Results: The prevalence of depression prevalence was 22.4%. Most participants were females aged 60-69 years (62.5%), Hausas (77.6%) and living with their spouses and children (77.3%). Gender, marital status, marital setting, socio-economic class, osteoarthritis and body-mass index were associated with depression. The predictors of depression were female gender (p=0.014, OR=1.401, CI=1.757- 2.591), widows/widowers (p=0.030, OR=4.533, CI= 1.186-17.317) and obesity (p=0.001, OR=5.644, CI=2.759-11.544).

Conclusion: The high prevalence of depression among this population highlights the need for screening. Females, widows/ widowers and obese geriatric patients are more likely to be depressed and should be targeted for screening in our busy outpatient setting.

Author

F Damagum 1, B A Grema 1, G C Michael 1
Beber Problema
Authors: Acuña Luis , Jara César , Gómez Mario
Published: July 2022

Insertos en una sociedad de consumo, el beber problema parece pasar desapercibido al ser validado como ejercicio del derecho a consumir y que la reflexión y la experiencia muestran que se trata de un fenómeno mas en el espectro mórbido de las dependencias, susceptible de detección y tratamiento. Este trabajo muestra algunas consideraciones teóricas y destaca elementos que pueden aplicarse en la psicoterapia de estos pacientes.
Derechos humanos y salud mental en América del Sur Situación de daño psicosocial y procesos de recuperación (crónica inicial)
Authors: Riquelme U. Horacio
Published: July 2022

Este ensayo aborda la impronta de los gobiernos cívico-militares en las sociedades de Argentina, Chile y Uruguay. Se plantea un estudio sistemático de la acción recíproca entre derechos humanos y salud mental.

Preguntas centrales: 1.- ¿Es posible expresar en forma clara y concisa las características de lesión psi-cosocial? 2.- ¿Es accesible a la comprensión la dimensión vivencial de los afectados y su entorno social? y 3.- ¿Existen vías de interacción social y cultural promisorias para superar los efectos de daño integral?Elementos estudiados de lesión psicosocial: a) Secuestro y “Desaparición forzada” de opositores al régi-men; b) Tortura física y psicológica sistemática c) Control y manipulación de los medios de comunicación y d) Exilio y desplazamiento forzado de personas.Basado en investigaciones de campo y documentales, este ensayo da curso a un análisis de las circunstan-cias de daño en individuos y comunidades en esa época y de su trato en cada sociedad.
Defining the Cultural and Creative Industry: an Exploration of the Nigerian Cultural and Creative Ecosystem
Authors: Alakwe Kizito-Ogedi
Published: July 2022

The recency of the cultural and creative industries and the cultural diversity existing among the nations of the world have caused many societies, organisations and governments to define the industry based on the peculiarities of their specific culture and environment. Government agencies like the UK Department for Culture, Media and Sports and multilateral institutions like UNCTAD (United Nations Conference on Trade and Development) have all defined the industry by leveraging on specific criteria that they developed for that purpose. As an industry sector in Nigeria, the cultural and creative industry recently received the attention it deserves when Nollywood (the Nigerian Film Industry) was listed as a significant contributor to the economy of Nigeria, which is Africa’s largest economy. This development has made it imperative to understand the components of the cultural and creative industry in Nigeria and leverage such information to define the industry in the Nigerian context. In conclusion, this paper posits that any definition of the cultural and creative industry must incorporate four essential elements: the producers, the regulators, creative cities and clusters and those industries that offer allied support services.
Economics of Joint Production and Implications for the Media and Cultural Industries: the Necessity of Application and Research
Authors:   Tsinghua University, Hang Min , Picard Robert ,   Oxford University
Published: July 2022

This article addresses an issue of joint production arising from the media and cultural industries. Joint production is a production process that yields two or more products simultaneously. In the media and cultural industries, the application of digital technology has made it possible for producers to generate products both online and offline, therefore, a common production process can yield an outcome for multiple platforms. This changing feature has brought with it many implications – from the managerial perspective, it has altered economic rationales guiding managers’ decision making on whether or not to cease production on the traditional platforms. The current study explores why different types of analysis are required in the joint production. This study introduces the concepts of shut-down, split-off and tipping points that need to be considered. The authors also propose an approach of timeline analysis that may move the investigation of joint production forward for the next steps.
Cultural Entrepreneurship and Spatial Distribution: a Case Study Analysis of Cuba
Authors:   Latin American Social Sciences Faculty, Cuba Program, Rojas-Martínez Janet , Carballo-Concepción Jorge-Alfredo ,   Latin American Social Sciences Faculty, Cuba Program
Published: July 2022

Entrepreneurship is a complex, dynamic and multidimensional phenomenon that transforms spaces and territories. The effects of this process on economic and social dynamics are increasingly evident in the Cuban context. However, there has not been a thorough examination of cultural undertakings, in their relationship with institutions, and in their profoundly transforming role. Therefore, the objective of this article is to theoretically explore the topic of the cultural entrepreneurship, as a factor of territorial reconfiguration, as well as to lay the foundations on future research and conceptualizations on the subject. This article highlights the benefits of the articulated management between institutions and entrepreneurs in the field of arts and culture, the importance of the spatial approach in studies on the subject, and the relevance to highlight the creativity and heterogeneity of the cultural entrepreneurs. The article contributes in a reflexive way to a theoretical and methodological approach to cultural entrepreneurship and the territorial synergies that take place in the process of artistic and cultural creation from the Cuban perspective.
COVID-19 as an Accelerator of Innovation, Management, Marketing and Communication in the Creative and Cultural Industry
Authors:   Porto University, Faustino Paulo
Published: July 2022

This essay intends to put forward some preliminary thoughts for academic research built on empirical data. The key question guiding this research is: How will COVID-19 drive innovation in the creative industry’s business model, and its marketing and communication strategies? Today, because of the crisis caused by the Coronavirus disease (COVID-19), humanity is being “forced” to make significant behavioural changes. In the creative and media industry, COVID-19 is already acting as an accelerator of innovation in several domains, from production to delivery and monetization. And the creative and media industry has no choice but to face the reality of COVID-19’s innovation accelerator effect on online and offline platforms. Technology must be seen as a complement to the business objectives of the creative and cultural activities, products and experiences. Also, analogue media and other creative and cultural products are not doomed; they have to be repositioned. It implies the adoption of technology and understanding that the basis of innovation lies in the way (i) a company organizes itself, (ii) its products are monetized and (iii) are delivered and promoted.
نامه‌ی ۱۲۳ نفر از درویشان و منسوبان شیخ علی خالص طالبانی در شهر سنندج به دولت عثمانی
Authors: AHMAD Hemin Omar
Published: July 2022

At the end of the nineteenth century and the final days of Ottoman authority, the border areas between the state of Iran and Ottoman empire experienced severe tensions. Part of the population under the power of Iran sought to be ruled by Ottoman authority due to the pressure of Iranian Shia government. The city of Sina (Sanandaj) was one of the cities from which some families of scholars had immigrated to Baghdad and Istanbul. This document of Ottoman archive which dates back to 1911 shows the effect of Qadri order led by the family of Sheikh Abdulrahman Talabani from Kirkuk whose followers in Sina required Ottoman Empire to accept them as the followers of the state. Among them, there were the Mufti of the city and 122 other figures of Sheikh and dervishes of the order.
Design and Realization of Solar-powered IoT-based Flood Early Warning System with Telegram Messaging, Auto-restart Watchdog, and Power Management
Authors: Uranus Henri P. , Adhinugroho Natanael R. , Yulian Dwi Heri , Mangunsong Rianto
Published: July 2022

A Flood is inevitable in some regions in Indonesia during rainy season. Flood can cause problems ranging from simple problem such as lightly flooded street to a complex one such as water that enters the house. For community living at river side, the flood often comes from excessive water due to rain in the upstream that outflows the river as drainage which can happen unnoticeably. An early warning system is needed to detect flood so that people who lived in a flood-prone area can be warned and be prepared to mitigate the flood. With the help of internet of things (IoT) technology, such a system can be made. In this work, an early warning system was developed using off-grid solar system as power source, ultrasonic sensor to detect water level, NodeMCU as microcontroller, and 4G modem to connect to the internet. The system uses Blynk as its IoT platform and sends alarm messages to locals using Telegram so they are vigilant. The system can detect how much the water level and categorizes it into preset alarm levels. Lab. experiments on the proposed system was performed using power from PV-module installed on the lab.’s rooftop. The system functionality works well for 3 weeks of experiments with battery voltage monitored to vary from 12 V at dawn to 13.7 V at daytime. The experiments show that the system exhibits water level measurement average relative error of 2.22% and accuracy of 97.78%. The system is also furnished with power management and auto restart self-healing functionality which were also observed to work well during the test. Measurements show that the system only consumes energy of 11.52 Wh/day which is equivalent to 8% of battery depth of discharge, hence the system can operate for 3.75 days without charging during successive rainy and cloudy days and has sufficient solar energy harvesting margin to cope with site imperfections like shading and soiling of the PV-module.
Utilization of Seaweed (Kappaphycus alvarezii) Flour as Filler in Making Tempeh Nugget
Authors: Cornelia Melanie , Kartika Nadya
Published: July 2022

Tempeh is high protein food product and has a distinctive soybean aroma which is less favorable. Tempeh can be processed into preferred food such as tempeh nugget. Tempeh has a soft texture, so it is necessary to add filler to improve the texture. The fillers are commonly used are cassava flour, wheat flour, and corn starch. Seaweed flour has high in dietary fiber are used as filler for nugget. The purpose of this research was to substitute cassava flour with10%, 20%, 30%, 40%, 50% seaweed flour and 0% as control nugget.  Physical testing was carried out on each tempeh nugget. Storage testing was carried out on 3 (three) types of tempeh nugget (0% control nuggets without preservatives, 0% control nuggets with preservatives, and the best formulation nugget without preservatives). Tempeh nugget with substitution 50% of seaweed flour was chosen as the best formulation which has the most similar texture, color, and frying shrinkage, compare to commercial chicken nugget and also resulted in higher value 9.88% of fiber, while 0% control tempeh nugget 4.24%. Storage test in the freezer (-20°C) showed that nuggets with 50% seaweed flour substitution could not maintain the physical quality of tempeh nuggets in one week compared to control nugget.
BANKALARIN KREDİ SİSTEMİ ÜZERİNE BİR OYUN TEORİSİ SİMÜLASYONU
Authors: TURGUT Ecem , UÇAN Okyay
Published: July 2022

Oyun teorisi, bir rekabet ortamında bir birey ya da grubun elde ettiği kazancın, bu rekabet ortamına katılan diğer birey ve grupların kararlarına bağlı olduğunu savunan matematiksel yaklaşım olarak tanımlanmaktadır. Bu açıdan değerlendirilince de oyun teorisi rekabetin matematiği olarak da ifade edilen bir stratejik karar alma aracı olarak karşımıza çıkmaktadır. Günümüz şartlarında rekabetin daha da artmasıyla birlikte oyun kuramı olarak da bilinen oyun teorisi öne çıkmaya başlamıştır. Özellikle de son zamanlarda asimetrik bilginin piyasalarda kendini göstermesiyle birlikte oyun teorisinin önemi daha da anlaşılmıştır. Bu açıdan değerlendirilince de oyun teorisi özellikle de asimetrik bilginin yaygınlık kazandığı bankacılık sektöründe, kredi alıp vermede bankaların kredi alan müşterinin yatırımı ve bu yatırımın geleceğiyle ilgili tam bilgiye sahip olmadıklarından dolayı, büyük bir önem arz etmeye başlamıştır. Bu doğrultuda bu çalışmada bankalar tarafında verilen kredilere yönelik genel stratejik yaklaşımlar geliştirilerek oyun teorisi çerçevesinde incelemelerde bulunulmuştur. Sonuçta en doğru stratejinin her iki tarafa da kredi uygulaması ve bunların da aldıkları kredileri geri ödemesi durumunda ortaya çıktığı anlaşılmıştır.
TÜRKİYE’DE 1991-2019 YILLARI ARASI BEBEK ÖLÜMLERİNİN SOSYOEKONOMİK BELİRLEYİCİLERİ
Authors: AKCAN Melike Buse , TELLİ ÜÇLER Yasemin
Published: July 2022

Bebeklerin ölüm oranı, ülkelerin başta ekonomik ve sağlık durumları ile ilgili olarak birçok ekonomik ve sosyal değişkenler ile yakından ilgilidir. Ekonomi ile birlikte sağlık sisteminin gelişmesi ve sosyoekonomik imkânların artmasının bebek ölümleri ile ilgili olduğu düşünülmektedir. Bu amaçla bebek ölümleri ile sosyal ve ekonomik değişkenler arasındaki ilişki ekonometrik yöntemlerle araştırılmıştır. Çalışmada bebek ölümünün ekonomik değişkenlerle ilişkisinin ölçülmesi için ekonomik büyüme ve enflasyon değişkenleri kullanılmıştır. Bebek ölümlerinin sosyal değişkenlerle ilişkisini ölçmek için ise okuma-yazma bilen çocuk sayısı ve yaşam beklentisi değişkenleri kullanılmıştır. Bu değişkenler 1991-2019 yılları arası zaman dönemi için toplanmıştır. Çalışmada bu ilişkilerin analizi için ise Granger Nedensellik Testine başvurulmuştur. Granger Nedensellik Testi sonuçlarına göre bebek ölümleri ile beraber ekonomik ve sosyal değişkenlerin tamamı ile tek yönlü nedensellik ilişkisi tespit edilmiştir.
İYİ DEVLET YÖNETİMİ YÜKSEK MAKROEKONOMİK PERFORMANSA NEDEN OLUR MU OECD ÜLKELERİNDEN BULGULAR
Authors: ÖZAYTÜRK Gürçem
Published: July 2022

Küresel kriz sonrasında mikro ve makro ölçekte gözler önüne serilen yönetim başarısızlıkları kurumsal iktisat tartışmalarının hararetlenmesine neden olmuştur. Bu nedenle son yıllarda kurumların ekonomik etkilerine olan ilgi canlanmıştır. Böylece hem ulusal hem firma düzeyinde iyi yönetişim kavramı temel politika önermelerinden biri haline gelmiştir.

Genel kabul daha iyi yönetişimin, daha yüksek düzeyde ekonomik ve finansal gelişmeye neden olacağı yönündedir. Literatürde kaliteli yönetişimin, bir ekonominin maruz kaldığı şokların etkisini sınırlayacağı, aynı zamanda karar alıcıların negatif şoklar ortaya çıktığında bunlarla başa çıkmalarını kolaylaştıracağı varsayılmaktadır. Bu çalışma iyi bir ekonomik performans ile yönetişim kalitesi arasında bir ilişki olup olmadığını araştırmaya odaklanmıştır. Bu amaçla 2002-2019 arası döneminde 33 OECD ülkesi için makroekonomik performans ve yönetişim kalitesi arasındaki ilişki, panel veri analizi kapsamında değerlendirilmiştir. Analiz sonuçlarına göre yönetişim kalitesi ile makroekonomik performans arasında iki yönlü nedensellik bulunmuştur. Katsayı tahminleri ise değişkenler arasındaki negatif ilişkiye işaret etmektedir.
The Impact of Clubfoot
Authors: Domett Kate , Colbert Alana , Chang Nigel
Published: July 2022

A detailed study of a young adult male burial from Bronze Age Thailand has revealed a series of significant pathological lesions, which, when contextualized in time and place, allow for insights not only into the life of this young man but also his community. Burial 671, represented by a near complete, well-preserved skeleton and a range of grave goods, was dated to 900–700 B.C. from the northeastern Thailand site of Ban Non Wat. Using the Bioarchaeology of Care Model, a detailed analysis of the lower limb pathological lesions, including a comprehensive review of relevant paleopathological and clinical literature, was undertaken. It is suggested this young man had congenital, bilateral clubfoot, as well as a recent, partially healed femoral midshaft fracture. These pathologies would have impacted his mobility and daily activities, but his skeleton indicates that he developed methods to adjust. Combining this assessment with an evaluation of his socio-environmental context, it is evident that this man, though he died young, was an integrated member of his community.

 

การศึกษาหลักฐานโครงกระดูกชายหนุ่ม สมัยสำริดในประเทศไทย พบหลักฐานรอยโรคพยาธิสภาพโบราณที่สำคัญ เมื่อพิจารณาถึงบริบทด้านเวลาและสถานที่ทำให้เกิดความเข้าใจเพิ่มขึ้นเกี่ยวกับวิถีชีวิตในอดีตทั้งของบุคคลและชุมชน กรณีศึกษาหลุมฝังพหมายเลข 671 ที่พบโครงกระดูกสภาพเกือบสมบูรณ์ร่วมกับวัตถุอุทิศหลากหลายประเภทจากแหล่งโบราณคดีบ้านโนนวัด ภาคตะวันออกเฉียงเหนือของไทย สมัยสำริด อายุประมาณ 2,900-2,700 ปีมาแล้ว ผลการวิเคราะห์รอยโรคที่พบบริเวณขา เปรียบเทียบกับรายงานผลการศึกษาพยาธิสภาพโบราณและการศึกษาทางคลีนิค ตามกรอบคิดเรื่องการดูแลในงานชีวโบราณคดี พบว่าชายหนุ่มเป็นโรคเท้าปุก หรือมีลักษณะเท้าผิดรูปทั้งสองข้างมาโดยกำเนิด มีรอยโรคที่แสดงถึงการแตกหักของกระดูกต้นขาที่พึ่งหายเป็นปกติ รอยโรคเหล่านี้น่าจะส่งผลกระทบต่อการเคลื่อนไหวและการทำกิจกรรมต่าง ๆ ในชีวิตประจำวัน แต่หลักฐานอื่นที่ปรากฏบนโครงกระดูกก็แสดงถึงพัฒนาการปรับตัวกับโรคดังกล่าวได้ในระดับหนึ่ง ชายหนุ่มคนนี้แม้ปรากฏหลักฐานว่าเสียชีวิตในวัยหนุ่ม แต่ก็ถือเป็นสมาชิกคนหนึ่งของชุมชนเมื่อประเมินร่วมในบริบททางสังคมและสิ่งแวดล้อม
Characterization of Casting Properties of Rare-Earth Modified A356
Authors: Can Dizdar Kerem , Sahin Hayati , Tezer Furkan , Dispinar Derya
Published: July 2022

Al-Si alloys are an attractive choice of light alloys due to their low density and high mechanical properties. The application areas include automotive and aerospace parts. With the increased requirements and demands on such applications, the researchers have focused on the enhancement of properties with the addition of novel alloying elements. In the last decade, modification of microstructure by rare-earth element additions has become popular. In this work, systematical tests were carried out by using fluidity test mold that has 8 arms with different thicknesses and tensile test mold that contains 10 bars to statistically analyze the mechanical properties. Different ratios ranging from 0.05 to 1 wt% of Er, Sc, Y, and V were added to Al-7Si alloys. The addition of 0.1 wt% Sc shows the highest fluidity whereas V additions have the lowest. Statistically, Sc addition revealed the highest reproducible results in terms of tensile properties where Y had the highest scatter. Er additions have the highest UTS and elongation at fracture.