bluuebunny/crossref_metadata_2025 huggingface dataset:
Caminhos da União Europeia
Authors: Mendes Lucas Bruno Amaral
Published: December 2023

A integração europeia iniciada em 1951, pelo Tratado de Paris, evoluiu de uma Comunidade Econômica do Carvão e do Aço (CECA) para uma Comunidade Econômica Europeia (CEE), em 1957 até uma União Europeia (UE), em 1993. O Projeto de Paz e Poder europeu se confronta com três visões principais sobre o futuro e sua integração, nomeadamente: Europa dos Estados, Europa dos Cidadãos e Europa das Repartições. Essas perspectivas possuem, em alguma medida, destaque na formação e elaboração do cenário europeu. Deles emergem as três esferas europeias, a externa sendo a pautada na política de poder, onde seus líderes nacionais, em nome de sua população, perseguem cada um seu poder e seus interesses, com os Estados possuindo maior destaque no Concerto Europeu; a esfera interna reflete os anseios funcionalistas de seus burocratas que, sob o regime dos tratados europeus, são sustentados e inspirados pelo espírito comunitário; por último, a esfera intermediária, congrega a busca dos interesses de cada Estado-membro a partir da Comunidade que, conjuntamente, ditam o formato e caminho da Europa. Neste trabalho, inferimos que a integração europeia, seja qual for, e se for o caso, possivelmente deve compreender sua realidade política, ou seja, ter consciência das disputas por seus valores, suas tradições, sua cultura e se de fato são ou serão uma nova Europa. Deste modo, buscamos evidenciar que a luta pela efetivação dos direitos fundamentais e a realização do ideal de Estado de Direito devem ser o sustentáculo da construção europeia.
Uji Aktivitas Antioksidan Ekstrak Bunga Rosella (Hibiscus Sabdariffa) Menggunakan Metode 1,1-difenil-2-pikrilhidrazyl (DPPH)
Authors: Fardani Roushandy , Rodiatullah Rodiatullah , Halid Idham , Atfal Bustanul
Published: December 2023

Antioksidan merupakan suatu senyawa yang dibutuhkan oleh tubuh untuk menangkal radikal bebas antioksidan ini dapat menghambat terjadinya reaksi oksidasi, dengan mengikat radikal bebas dan molekul yang sangat reaktif. Salah satu senyawa yang dapat menangkap radikal bebas yaitu turunan Flavonoid. Tanaman bunga rosella mengandung senyawa flavonoid yaitu golongan antosianin. Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antioksidan alami ekstrak bunga rosella dengan metode DPPH (1,1-Diphenyl-2-Picrylhidrazyl). Pengukuran absorbansi dari kandungan flavonoid yang terdapat pada bunga rosella menggunakan psektrofotometri Uv-Vis. Uji aktivitas antioksidan dengan metode DPPH dan parameter nilai IC50, untuk menghitung aktivitas antioksdian menggunakan persamaan regresi linear. Hasil aktivitas antioksidan dari bunga rosella yaitu 1.01 μg/mL dan aktivitas antioksidan dari vitamin C sebagai pembanding yaitu 43.29 μg/mL. Aktivitas antioksidan pada bunga rosella masuk kedalam kategori sangat kuat dan untuk vitamin C termasuk kedalam kategori sangat kuat.
State Interference With the Scope of Parental Responsibilities – Comparative Legal Analysis
Authors: Prucnal-Wójcik Marta
Published: December 2023

RESEARCH OBJECTIVE: The article presents a comparative analysis of legal regulations in selected (according to the author’s research interests) European countries regulating issues related to state interference with the scope of parental authority/responsibility, the grounds for this interference and the forms of modification of parental rights and responsibilities.

THE RESEARCH PROBLEM AND METHODS: The author is looking for answers to questions: In what circumstances the interference of state authorities in the sphere of parental rights is possible/necessary? What form can such interference take in the laws of selected countries? Who has the right/obligation to request such interference? The author used the method of analysis of ad- equate legal provisions of selected countries.

THE PROCESS OF ARGUMENTATION: Analysing the provisions in force in the internal legislation of Poland, Hungary, Norway and Sweden, the author presented adopted legal solutions regulating issues related to the scope of interference with the parental responsibility/authority of the child’s parents in the event of its improper implementation.

RESEARCH RESULTS: The analysis of legal provisions regulating the issue of parental responsibilities indicates that each of the four legal systems examined provides for situations in which it is necessary for state authorities to interfere in the sphere of parental rights and responsibilities.

CONCLUSIONS RECOMMENDATIONS AND APPLICABLE VALUE OF RESEARCH: Presented considerations constitute a general overview of the regulations in force in individual countries and, as such, are only an introduction to in-depth reflection on the optimization of the subject scope of social policy.
Kryzys rodziców dziecka z niepełnosprawnością słuchu jako efekt społecznych uwarunkowań
Authors: Doroszuk Joanna
Published: December 2023

CEL NAUKOWY: Celem naukowym artykułu jest ukazanie zjawiska kryzysu rodziców dzieci z niepełnosprawnością w perspektywie interpretacji zjawiska głuchoty.

PROBLEM I METODY BADAWCZE: Główny problem badawczy: Jakie działania sprzyjają budowaniu sieci wsparcia wśród rodziców dzieci z niepełnosprawnością słuchu, które uczęszczają do szkół masowych? Zastosowaną metodą badawczą jest badanie w działaniu. W artykule zaprezentowano analizę jednej z zastosowanych technik badawczych – gry biograficznej.

PROCES WYWODU: Analizie poddano zjawisko kryzysu rodziców dzieci z niepełnosprawnością słuchu w perspektywie modeli interpretacyjnych głuchoty: medycznego oraz społeczno-kulturowego.

WYNIKI ANALIZY NAUKOWEJ: Analiza materiału badawczego dotyczyła znaczeń nadawanych swojemu rodzicielstwu przez rodziców dzieci z niepełnosprawnością słuchu oraz trudności, jakie napotykają w jego obszarze. Wyłonione zostały kategorie: dążenie do mowy, upór, poświecenie oraz społeczne niezrozumienie, które mają znaczenie dla doświadczania przez rodzica kryzysu osobistych wartości oraz kryzysu rzeczywistego.

WNIOSKI, REKOMENDACJE   I APLIKACYJNE   ZNACZENIE   WPŁYWU   BADAŃ: Niepełnosprawność słuchu dzieci badanych ma znaczenie dla funkcjonowania ich systemów rodzinnych, nie determinuje jednak bezpośrednio doświadczanych kryzysów. Bardziej znaczące w tym obszarze wydają się postawy otoczenia społecznego. Świadomość rodziców wpisuje się w model społeczno-kulturowy głuchoty, zaś ich doświadczenia społeczne związane są z modelem medycznym.
Research on User Experience during Interactions with Mobile Applications for Diabetics
Authors: Bajda Przemysław , Baliński Rafał , Dzieńkowski Mariusz
Published: December 2023

The purpose of this study was to assess the influence of the appearance and structure of the application interface on task completion speed and user experience. Two data collection methods were used in the study: eye tracking and the System Usability Scale (SUS) questionnaire. Eye tracking provided information on eye movement and fixation while using the application, while the SUS questionnaire helped evaluate the overall usability level and user satisfaction. Three applications were examined (mySugr, Diabetes diary control from Google Play, and one proprietary application implemented for the purposes of the study. It was found that the proprietary SugarCare application characterized by a simple, modern, and readable interface achieved the highest results in terms of task completion times and SUS questionnaire scores. The mySugr application, which also has a clear and simple interface, took the second place. The Diabetes diary control application performed the worst, as it had a complex and less user-friendly interface. On the basis of the obtained results, mobile applications for diabetics with a clear interface proved to accelerate the task completion process and have a positive impact on user experience. These conclusions stem from the analyses of the metrics used indicating the benefits resulting from accessibility of simple and intuitive application interfaces in terms of efficacy and user satisfaction.
A comparative analysis of the Flutter and React Native frameworks
Authors: Markowski Mateusz , Smołka Jakub
Published: December 2023

The article describes a comparative analysis of the resource usage performance of mobile applications developed using Flutter and React Native frameworks. The purpose of this study was to see which technology is more efficient. The study consisted in creating two mobile apps with the same functionalities and then comparing usage of the following resources: Virtual Memory (VIRT), Shared Memory (SHR), Central Processing Unit (CPU), Resident Set Size (RES) and Memory (MEM). The functionality of  the application consisted of actions on the GUI. The test was conducted on a Huawei P20 Lite smartphone, using the Android Debug Bridge (ADB) tool and custom scripts in the Bash shell language. The results do not clearly indicate which technology is more efficient.
Performance analysis of REST API technologies using Spring and Express.js examples
Authors: Wicha Maciej , Pańczyk Beata
Published: December 2023

The purpose of this article is a comparative analysis of two technologies for building applications in REST architecture. A Java-based development framework - Spring, and a framework designed for JavaScript language and Node environment - Express.js were analyzed. The test application was designed and implemented in both studied technologies. Using the Apache JMeter tool, HTTP request processing times were measured by operating on simple text data. The experiment was based on 5 scenarios repeated for a different number of users in the range of 10 to 100, with a constant number of executed requests to the server. The analysis conducted showed that the application implemented in Express.js handles HTTP requests up to 249% more efficiently than its counterpart in Spring.
Comparison of Machine Learning Algorithms on Classification of Covid-19 Cough Sounds Using MFCC Extraction
Authors: Faisal Mohammad Reza , Hidayat Muhammad Thoriq , Kartini Dwi , Indriani Fatma , Budiman Irwan , Saragih Triando Hamonangan
Published: December 2023

Early detection for COVID-19 has now been widely developed. One of the methods used is cough audio detection. This research aims to classify cough audio. Audio feature extraction is performed using MFCC to obtain numerical features. Feature classification is done using SVM, Random Forest, and Naive Bayes methods. Evaluation is done to find the best classification method. The evaluation results in this study show that SVM Kernel RBF produces the best evaluation value with an AUC value of 0.657715.
REFORMASI MANAJEMEN KELEMBAGAAN DAN KURIKULUM PENDIDIKAN MUHAMMAD ABDUH DI MESIR
Authors: Samsul Bahri  , Erni Qomariyah
Published: December 2023

The research aimed to understand the reforms implemented by Muhammad Abduh in Egypt and to analyze the restructuring of institutional management and curriculum he conducted. The research methodology was a literature review with content analysis to reveal Muhammad Abduh's thoughts related to his mission. The findings indicate that Abduh's thoughts significantly influenced the modernization of Islamic education, particularly at al-Azhar University. He stressed the need to integrate modern sciences and technology with Islamic teachings. These reforms were intended to strengthen Islam's position amidst the advancement of science and modernization challenges.
La construcción del tiempo. Metáforas temporales en la lengua, la literatura y la filosofía
Authors: Huelva Unternbäumen Huelva Unternbäumen
Published: December 2023

¿Qué es el tiempo? Pocas preguntas han suscitado tanto interés en la filosofía, en la física y, más recientemente, en las ciencias sociales, la psicología y las ciencias cognitivas como esta acerca de la esencia del tiempo. En esta obra de carácter ensayístico, el autor se contrapone a las posiciones tradicionales según las cuales lo que llamamos tiempo es una propiedad innata de la mente humana o una cualidad inmutable del mundo externo. El tiempo debe ser entendido y analizado, más bien, como el resultado de un proceso multifacético de construcción, que posee, por lo menos, una dimensión social, una dimensión semiótica y una dimensión cognitiva. Este libro se centra en las dos últimas dimensiones y demuestra que la metáfora conceptual es el principal mecanismo mental de que dispone el ser humano para construir el concepto de tiempo. Todo lo que pensamos, todo lo que sabemos y sabemos decir e, incluso, todo lo que sentimos acerca del tiempo es el resultado de esta construcción metafórica. Y, por añadidura, también todo lo que sabemos sobre el uso social del tiempo, es decir, sobre la ordenación de nuestras acciones y actividades en sociedad. En palabras del autor, «el tiempo es una de nuestras grandes metáforas, quizás la más trascendental de todas».
The effect of Aerosil A-300 on the growth of bacteria Lactobacillus plantarum, Bifidobacterium adolescentis and Streptococcus lactis
Authors: Guzhvynska S. О. , Kornieikov О. M. , Oleshko А. Yu. , Busol V. O.
Published: December 2023

The article presents data on the effect of Aerosil A-300 on the growth of bacteria Lactobacillus plantarum No. 7-317, Bifidobacterium adolescentis No. 17-316, Streptococcus lactis No. 5. The results of studies have shown that the most optimal for the growth of bacteria content of Aerosil A-300 in the environment is 2.0%. It has been found that when Aerosil was added to nutrient media, bacteria grew and actively accumulated a significant number of viable cells: 3.8–4.5×107 CFU/cm3 (control 1.1–2.5×107 CFU/cm3) according to the average technological parameters pH 7.0 and the temperature of 37 ℃. Studies have shown that the relative increase in the number of cells, by which we assessed the effect of Aerosil on growth, was in Lactobacillus plantarum No. 7-317 (87.5 ± 12.0), which is 23% higher than control, in Bifidobacterium adolescentis No. 17-316 — (79.2 ± 11.9), which exceeded the control data by 14%
Pelatihan Ketrampilan Kreasi Nugget Lele Bergizi Kepada Ibu Balita Dan Penyuluhan Gizi Untuk Pencegah Kejadian Stunting Di Wilayah Gunungpati
Authors: Widayani Sus , Triatma Bambang , Agung Pratama Muh Nur , Setyorini Endah
Published: December 2023

The danger of stunting threatens Indonesian children. The danger of stunting threatens Indonesian children. Stunting is when toddlers are shorter than their age, caused due to chronic malnutrition at 1000PHK from fetus to 2 years of age. The physical and brain development of stunted children is hampered and susceptible to disease, resulting in difficulty achieving. When adults are easily overweight so they are at risk of developing degenerative diseases. At the productive age, stunting children earn 20% less than children with optimal growth. Stunted children reduce the country's gross domestic product by 3%. For Indonesia, the loss due to child editing reaches Rp. 300 trillion per year. It is very necessary to prevent stunting, one of which is by doing the dedication to help mothers of toddlers provide nutritious food supplies to their toddlers so that they are healthy and have a good nutritional status so as to prevent stunting in their area. Fish is processed food that attracts and likes children (Widayani and Triatma, 2018). Reinforcement with a lack of attention to children's consumption, and often children eat only for pleasure. This is also supported by the low level of fish consumption in the city of Semarang (11.3 kg / year / capita which should have been 31.4 kg / year / capita). If this condition is allowed to drag on, toddlers will grow up to become children who do not like to eat fish so that the fulfillment of animal protein needs in the body is lacking. The aim is to provide nutrition education and training on healthy and nutritious catfish nuggets processing to prevent stunting. Methods of counseling and training for mothers of toddlers so that they are skilled at creating catfish nuggets. The nugget-making practice adds to the enthusiasm of toddler mothers. There was a change in the mindset of the mothers after the nutrition counseling activities and training in processing nutritious healthy nuggets. The mothers hope to be given back counseling and practice of fish processing and nutritious food on a regular basis. The hope in the future is that children will love to eat fish so that a nutritionally aware society will be realized
Pemberdayaan Keluarga Dalam Pengembangan Ternak Puyuh di Desa Pekik Nyaring Kecamatan Pondok Kelapa Kabupaten Bengkulu Tengah
Authors: Rita Wismalinda  , Catur Herizon  , Neli Definiati
Published: December 2023

Quails breeding is easy to cultivate, can produce in a relatively short time and does not require a prominent location. Besides, male quail and rejected livestock are very well sold in the market. The obstacle to the development of quail so far is the high cost of concentrate feed with prices that tend to fluctuate so that the nutritional needs of quail have not been fulfilled, which in turn has an impact on production. Knowledge and skills of quail breeders are required in the management of quail rearing. Selection of seeds, feeding with good nutrition by utilizing feed ingredients from local sources is the right solution. This activity aims to increase knowledge of the PKK (group of women in the village) to develop quail farms. Activities are carried out in the form of program socialization and counseling. As a result, the activity has run smoothly; women of the PKK Pekik Nyaring can understand the management of quail breeding, especially the selection of seeds and the provision of quality feed with good nutrition
EFFECT OF NITROGEN, PHOSPHOROUS AND POTASSIUM LEVELS ON THE PRODUCTIVITY OF INDUSTRIAL POTATOES
Authors: K. G. Saaseea  , N. J. K. Al-a'amry
Published: December 2023

The experiment was conducted using Potato( Solanum tuberosum L.) at the eastern Radwaniyah at private field during fall season 2020/2021 and spring 2021 to study the effect of nitrogen levels to 350, 275, 200 kg N h-1 ( N1, N2, N3) and phosphorous to 100, 180, 360 kg P2O5 h-1 ( P1, P2, P3) and potassium to 100, 200, 300 kg K2O h-1 ( K1, K2, K3) to vegetative growth and yield of industrial potato, The seeds of the hybrid potato Sinora, Class A, were planted in the fall season on 15/9/2020 and Elite in the spring season on 31/1/2021. The experimental fertilizers were added in four batches and in proportions according to the stages of plant age, Factorial experiment with RCBD using three replications. The results showed that changing the levels of the elements used to N3, P3, K3 led to a significant increases in most traits of vegetative growth for both seasons, while the change of phosphorous and potassium levels to P2 and K3 had a significant effect on the quantitative and qualitative yield for both seasons. The N1P2K3 interaction gave the highest marketable tuber weight, marketable yield plant-1, total yield for the fall and spring seasons, and the highest percentage of dry matter in tubers in the fall season.
AUTOMEDICAÇÃO: IMPACTOS NO TRATAMENTO MÉDICO E DIAGNÓSTICO DA DOENÇA
Authors: Souza Lisboa Filho Laécio de , Sherman Pereira Lima Alisson , Do Amaral Noronha de Figueiredo Gomes Bruna , Amaral Rodrigues de Oliveira Marcelle , Lins e Silva Barbosa Sarah , Barbosa Rodrigues de Souza Manuela
Published: December 2023

Este artigo tem por objetivo analisar o perfil de uma amostra da população na região metropolitana do Recife que praticam a automedicação e identificar os riscos imediatos e futuros trazidos pela automedicação. A presente pesquisa de opinião pública foi realizada com participantes não identificáveis por meio da aplicação do questionário online gerado mediante a utilização da ferramenta Formulários Google. Conclui-se que automedicação é extremamente comum na região metropolitana do Recife aliado a grande presença da internet neste hábito, em que a maioria dos participantes ativamente procuram instruções sobre o uso dos medicamentos e, apesar de terem acesso virtual aos riscos e prejuízos da automedicação, ainda insistem nessa prática.
Etika Pendidik dan Peserta Didik Dalam Perspektif Hadist
Authors: Agustiana Sylvia Putri , Muslimin Amirudin , Rahmawati Ana
Published: December 2023

Berbicara mengenai etika pendidik dan peserta didik dalam perspektif hadist, tidak lepas dari perkataan dan perbuatan yang menjadi dasar beretika. Tujuan penelitian ini adalah bagaimana cara beretika seorang pendidik kepada peserta didik maupun cara beretika seorang peserta didik kepada pendidik yang diatur dalam perspektif hadist menurut hadis Imam Tirmidzi, Ibnu Majah, Dan Imam Bukhori. Jenis riset yang digunakan adalah penelitian kepustakaan sebagai dasardengan literasi (dokumen) berupa buku hadist tarbawiy. Metode analisis data dengan analisis isi dan induktif. Hasil penelitian menunjukan bahwa etika pendidik dan peserta didik menurut hadist yang diriwayatkan oleh imam tirmidzi hadits ini mengajarkan kepada pendidik dan peserta didik untuk membaca doa sebelum memulai dan mengakhiri pembelajaran, Didalam kelas, peserta didik hendaknya tidak mengganggu temannya, menurut  ibnu majah pendidik pendidik dan peserta didik memiliki ikatan yang baik dalam kegiatan mengajar, menurut imam bukhori pendidk dan peserta didik dapat mencontoh perilaku Nabi Muhammad.
Peran Pendidikan Agama Islam Terhadap Pembentukan Karakter Siswa SMP Paramarta Unggulan Ciputat Tangerang Selatan
Authors: Abnisa Almaydza Pratama , Ihsan Muhammad
Published: December 2023

Pendidikan agama islam merupakan suatu usaha yang direncanakan melalui penanaman nilai-nilai islam dalam jiwa, rasa, dan pikiran. Sehingga pendidakan agama islam menjadi suatu system yang bisa membentuk sikap dan kepribadian seseorang yang beriman dan bertaqwa kepada Allah swt. Pendidikan karakter menjadi sebuah jawaban yang tepat dalam menghadapi permasalahan-permasalahan yang terjadi seperti yang telah disebutkan diatas dan sekolah sebagai lembaga pendidikan diharapkan bisa mewujudkan misi dari pendidikan karakter tersebut. Karakter tanggung jawab dapat berbentuk mengerjakan soal, mengikuti kegiatan pembelajaran sampai selesai. Namun fenomena pada saat ini kebanyakan peserta didik yang tidak mengerjakan soal dengan baik dikarenakan banyak peserta didik yang lebih suka bermain di kelas dan tidak mendengarkan guru pada saat proses pembelajaran dikarenakan peserta didik lalai dalam tanggung jawabnya bahwa tanggung jawab peserta didik adalah belajar dan kebanyakan jaman sekarang peserta didik lebih suka bermain daripada belajar dirumah.
Status keberlanjutan penyediaan air di Sub DAS Cikeruh, bagian hulu DAS Citarum, Jawa Barat
Authors: Dewi Riezcy Cecilia , Hidayat Yayat , Suheri Asep
Published: December 2023

Neraca air atau ketersediaan air yang tidak sepadan dengan kebutuhan air yang terus meningkat menjadi suatu persoalan yang sering ditemukan. Sub DAS Cikeruh adalah salah satu sisi hulu DAS Citarum yang mengalami defisit air. Permasalahan tersebut memerlukan alternatif kebijakan dalam mewujudkan penggunaan sumber daya air secara lestari. Penelitian bertujuan menganalisis indeks dan status keberlanjutan penyediaan air pada Sub DAS Cikeruh,  identifikasi atribut sensitif pada setiap dimensi keberlanjutan, yaitu dimensi ekologi, ekonomi, sosial dan kelembagaan. Metode analisis data menggunakan teknik MDS (Multi-Dimensional Scaling) menerapkan software Rapfish. Data yang dipakai mencakup data primer dan sekunder. Pengambilan data primer melalui interviu dengan kuesioner dan pertanyaan terstruktur terhadap stakeholder. Hasil analisis memperlihatkan  tingkat keberlanjutan penyediaan air di Sub DAS Cikeruh secara umum diklasifikasikan cukup berkelanjutan (indeks 57,68%). Analisis leverage menggambarkan sepuluh atribut yang begitu mempengaruhi tingkat keberlanjutan, yakni pemeliharaan catchment area, ketersediaan air, ketersediaan dana, sumber daya ekonomi lainnya, pendapatan petani, motif perpindahan kepemilikan lahan, pemahaman masyarakat, partisipasi masyarakat, koordinasi antar lembaga, dan kerja sama lembaga. Dengan mengoptimalkan atribut yang paling sensitif, maka tingkat keberlanjutan penyediaan air dapat ditingkatkan.
Analisis kondisi sanitasi pemukiman di daerah pesisir (studi kasus: Muaro Lasak, Kota Padang)
Authors: Rinaldi Rinaldi , Febriani Vita , Razak Abdul , Handayuni Linda , Yuniarti Elsa
Published: December 2023

Requirements for good environmental health in a residential area are characterized by the availability of access to sanitation facilities. Muaro Lasak, Rimbo Kaluang Village, Padang City is a coastal area, as well as a tourist location in Padang City. The aim of the research was to determine the condition of sanitation facilities, healthy behavior, and the water quality in Muaro Lasak. Qualitative and quantitative data were collected to obtain complete data. The assessment indicators consist of waste disposal facilities, latrines and public facilities that support tourism, as well as water quality (pH, dissolved solids/TDS, and dissolved oxygen levels/DO) of the river that flows into Muaro Lasak.. The results of the research show that there are good latrines available in every resident's house and public latrines so that defecation is no longer in the sea. There are rubbish disposal facilities available but they are not functioning optimally. Regarding the quality of sea water, such as: the pH still meets the quality standard (6.38), the oxygen content (DO) is 3.35 ppm (moderately polluted), while the dissolved solids (TDS) still meets the quality standard at 892.75 ppm.
Pemilihan alternatif pengolahan air lindi untuk TPA Nusa Lembongan, Bali dengan proses hierarki analitik (AHP)
Authors: Siregar Farhan Hadi , Jatmoko Muhammad , Adinda Aulia Risky , Dalimunthe Rika Chairani , Sari Mega Mutiara , Suryawan I Wayan Koko
Published: December 2023

Sampah yang dihasilkan di Nusa Lembongan diolah dengan cara open dumping. Open dumping cenderung menimbulkan dampak negatif terhadap lingkungan, salah satunya lindi. Lindi akan berdampak pada ekosistem sekitarnya jika tidak aman. Pengolahan dapat diterapkan dengan berbagai cara, salah satunya kolam stabilisasi limbah. Namun teknologi ini tidak akan cukup untuk menambah pengolahan lebih lanjut. Tujuan dari penelitian ini adalah menentukan teknologi pengolahan yang tepat untuk pengolahan lindi selanjutnya di TPA Nusa Lembongan. Penelitian ini menggunakan studi literatur dan proses hirarki analitik untuk pengambilan keputusan. Ada tiga alternatif yang diberikan, yaitu biofilter, lahan basah, dan reaktor baffle anaerobik (ABR). Kriteria yang digunakan adalah estimasi biaya, luas lahan, dan tunjangan BOD. Alternatif penggunaan ABR memiliki nilai bobot paling tinggi dibandingkan kedua teknologi lainnya. Hal ini karena ABR membutuhkan luas lahan yang lebih rendah dibandingkan dua alternatif lainnya. Hal ini sesuai dengan keterbatasan lahan yang tersedia di Nusa Lembongan.
ASSESSING THE IMPACT OF CREATIVE INDUSTRIES DEVELOPMENT ON CULTURAL HERITAGE AND TOURISM
Authors:   Northwestern Institute of Management of RANEPA, St. Petersburg, Russia, Shamakhov Vladimir A. , Burlov Dmitry I. ,   Northwestern Institute of Management of RANEPA, St. Petersburg, Russia; St. Petersburg University of Management Technologies and Economics, St. Petersburg, Russia
Published: December 2023

This article is devoted to the analysis of the impact of the development of creative industries on the spheres of cultural heritage and tourism. The key concepts of creative industries, their role in the preservation and popularization of objects of cultural and historical significance, as well as their contribution to increasing the tourist attractiveness of regions are examined. It is noted that creative industries play an important role in the processes of revitalization, reconstruction and creation of new uses for cultural monuments. In addition, the development of creative industries contributes to the formation of unique cultural experiences that increase tourist interest in specific destinations. It is concluded that there are close relationships between the creative economy, heritage and tourism. Effective strategic partnership in this area opens up new opportunities for the integrated development of territories.
Prognostic evaluation of relapse based on squamous cell carcinoma antigen, CXCR2, and CD44V6 blood levels in patients with Stage I–II squamous cell lung cancer
Authors: Tahanovich Anatoli D. , Kauhanka Mikalai M. , Rutkovskaya Zhanna A. , Khotko Ekaterina A. , Gotko Oxana V. , Prokhorova Violetta I.
Published: December 2023

Lung cancer, the leading cause of cancer-related mortality, predominantly exists as non-small cell lung cancer, accounting for approximately 85% of cases and comprising adenocarcinoma, squamous cell carcinoma (SCC), and large cell carcinoma as the three most prevalent histological subtypes. This study focused on investigating pre- and post-operative concentrations of SCC antigen in blood serum, as well as the percentage of CXCR2-containing lymphocytes and CD44v6-containing monocytes in blood cell populations among patients with Stages I–II squamous cell lung cancer (SCLC) within 1 year after tumor resection. The primary objective was to assess their potential for predicting relapse. The study cohort comprised 57 patients (32 men and 25 women) with newly diagnosed squamous cell lung cancer (21 at stage I and 36 at stage II). Following tumor resection, categorized as R0 in terms of surgical intervention, all parameters were examined before surgery and at 3 weeks, 3 months, and 6 months postoperatively. Analysis revealed that the probability of relapse could be accurately predicted, ranging from 68.4% to 89.5%, based on differences in SCC antigen concentration, the percentage of lymphocytes with CXCR2, and monocytes with the CD44v6 receptor during various post-operative intervals. Subsequent regression analysis and the formulation of a combined model incorporating the above-mentioned parameters led to an enhanced predictive value for tumor recurrence, reaching 96.5% accuracy (with specificity at 95.6% and sensitivity at 100%). These results indicate the potential utility of the combined model as an additional marker for predicting postoperative relapse in patients with Stage I–II SCLC.
ASSESSING THE ROLE OF FORMAL EDUCATION IN PROMOTING ENTREPRENEURSHIP
Authors: Osman Siddiq Abekah , Emole Emmanuel Onuoha , Onu Emmanuel Valentine
Published: December 2023

Entrepreneurship has been an economic tool for many governments, especially those facing unemployment challenges. Ghana is facing high unemployment among its youth. Various administrations have implemented policies, including the National Youth Employment Program and the YouStart Program, to solve the unemployment challenge. These initiatives, however, have yet to solve unemployment. This study examines the role of formal education in fostering entrepreneurship. Data were collected using a quantitative approach through a structured questionnaire survey administered to 140 entrepreneurs in Ghana’s Sunyani Municipality. The data were analyzed using SPSS version 25. Correlational analysis was performed to examine the relationship between formal education and entrepreneurial performance. The study findings show that entrepreneurial-based education, not only formal education, helps graduates successfully establish and operate their own businesses. This contributes immensely to reducing unemployment. The results also reveal a weak positive correlation between formal education and entrepreneurial performance; however, the observed correlation was not statistically significant. Thus, formal education may influence entrepreneurial performance, but other variables may have a greater influence. The implications of these results highlight the importance of equipping students with entrepreneurial knowledge and skills to help them succeed as entrepreneurs. This can boost economic growth and lower unemployment. The study's implications go beyond Ghana, as many nations struggle with unemployment. Findings form this research would drive policy-making and educational restructuring efforts to promote entrepreneurship and reduce global unemployment. The authors recommended modifying the existing educational curriculum to include more emphasis on entrepreneurship education, spanning from primary to higher education levels.
THE PERFORMANCE OF SMALL AND MEDIUM ENTERPRISES IN YEMEN: A CROSS-SECTIONAL STUDY
Authors: Saleh Mugaahed Abdu Kaid , Manjunath K. R.
Published: December 2023

Due to the importance of the contribution of Small and Medium Enterprises (SMEs) towards development worldwide, researchers in different contexts have investigated the development of SMEs and how economic development can be driven forward by supporting the SME sector. However, when it comes to lower-income economies, literature is scant in investigating the performance and the development of the contribution of SMEs towards economic development in lower-income economies. Hence, the aim of this article is to explore the extent and status of small and medium enterprises in Yemen as a lower-income economy and how their performance varies according to their characteristics. The article adopts cross-sectional quantitative methodologies, it relies on primary data collected conveniently from 400 owners and managers of manufacturing SMEs in Yemen. Descriptive analysis is used to explore the extent of SMEs' performance, and further, variance analysis using Independent Sample t-test and One Way ANOVA in order to explore the variance in the performance according to the variance of enterprise characteristics. The findings indicated a low extent of business performance among manufacturing SMEs, where the mean score of the overall extent ranges from 4.94 to 5.06 out of 7. Further, The result of running One Way ANOVA revealed that the scope of operation, age, and position of managers, in addition to owning a share of enterprises, significantly contribute to the variance in the business performance among manufacturing SMEs (P < 0.05). These results can benefit the managers and owners of SMEs in Yemen and other similar economies by focusing on the extent of performance that their management can target. The implication of this research is summarized by discussing the performance of SMEs in lower-income economies to draw the attention of authors and scholars toward investigating the role and contribution of SMEs in economic development and welfare in lower-income economies.
Development of patient-specific 3D printed implants for total knee arthroplasty
Authors: Ramavath Dasharath , Yeole Shivraj Narayan , Kode Jaya Prakash , Pothula Narendra , Devana Sudheer Reddy
Published: December 2023

Aim: Arthritis is a degenerative condition characterized by the progressive deterioration of the knee joint, leading to aches, rigidity, and decreased mobility. Total knee arthroplasty (TKA) surgery is performed to alleviate pain for restoring activity in these patients. TKA is carried out due to natural wear of the cartilage and meniscus or by sudden impact at the knee joint area. The surgical procedure involves careful planning, precise bone cuts, and insertion of artificial components made of metal alloys and high-density polyethylene. However, conventional manufacturing of customized knee implants involves time and cost. This work aims to present the application of three-dimensional (3D) printing for developing individualized knee implants for TKA and the challenges faced during it. Methods: Morphometry of the knee joint varies among different populations, including Indian and Western, which pose challenges during the surgery as accurate alignment and implant sizing are crucial for optimal outcomes. A female patient’s pre-surgery computed tomography (CT) scan is considered to identify the disease and to find region of interest (ROI) such as knee joint. Process involves converting scanned data to a file format for 3D printing via computer-aided design (CAD). Results: The patient’s CT scan data is processed to obtain the CAD models of knee joint and standard triangulation language (STL) file. Additional geometries and noise present near the region are removed to get ROI. Open loops and overlapping triangles are rectified in the STL file. Based on the morphometry of the bone, resection is done to obtain the CAD models of knee implants. 3D printing of the knee joint and implant prototypes is then obtained using fused deposition modelling (FDM). Line layers on the printed implant prototype are seen. Conclusions: Patient-specific 3D printed knee joint implant prototypes are successfully obtained using FDM. Challenges faced during the work are successfully worked out.
Current roles of artificial intelligence in ophthalmology
Authors: Keskinbora Kadircan H.
Published: December 2023

Artificial intelligence (AI) studies are increasingly reporting successful results in the diagnosis and prognosis prediction of ophthalmological diseases as well as systemic disorders. The goal of this review is to detail how AI can be utilized in making diagnostic predictions to enhance the clinical setting. It is crucial to keep improving methods that emphasize clarity in AI models. This makes it possible to evaluate the information obtained from ocular imaging and easily incorporate it into therapeutic decision-making procedures. This will contribute to the wider acceptance and adoption of AI-based ocular imaging in healthcare settings combining advanced machine learning and deep learning techniques with new developments. Multiple studies were reviewed and evaluated, including AI-based algorithms, retinal images, fundus and optic nerve head (ONH) photographs, and extensive expert reviews. In these studies, carried out in various countries and laboratories of the world, it is seen those complex diagnoses, which can be detected systemic diseases from ophthalmological images, can be made much faster and with higher predictability, accuracy, sensitivity, and specificity, in addition to ophthalmological diseases, by comparing large numbers of images and teaching them to the computer. It is now clear that it can be taken advantage of AI to achieve diagnostic certainty. Collaboration between the fields of medicine and engineering foresees promising advances in improving the predictive accuracy and precision of future medical diagnoses achieved by training machines with this information. However, it is important to keep in mind that each new development requires new additions or updates to various social, psychological, ethical, and legal regulations.
Cola rostrata K. Schum. constituents induce cytotoxicity through reactive oxygen species generation and mitochondrial membrane depolarisation
Authors: Ajayi Babatunde E. , Oboh Bola , Minari Joseph B. , Sexton Darren W. , Sarker Satyajit D. , Fatokun Amos A.
Published: December 2023

Aim: While the traditional use of Cola rostrata in treating illnesses and diseases has not been reported, the presence of cytotoxic principles has been reported in phylogenetically and biogeographically related species within the Cola genus. This study, therefore, evaluated the cytotoxic potential of extracts of the plant, and the associated cellular and molecular mechanisms. Methods: Activity-based fractionation of the extracts was carried out and cytotoxicity was assessed in the human cervical cancer cell line, HeLa, and the transformed human lung cell line, MRC5-SV2, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay complemented with brightfield imaging. The 2ʼ,7ʼ-dichlorofluorescein diacetate (DCFDA) assay was used to assess induction of cellular reactive oxygen species (ROS), while flow cytometry of 5,5ʼ,6,6ʼ-tetrachloro-1,1ʼ,3,3ʼ-tetraethyl-imidacarbocyanine iodide (JC-1)-stained cells assessed the loss of mitochondrial membrane potential (∆ΨM). Gas chromatography-mass spectrometry (GC-MS) analysis was carried out on an active fraction. Results: Extracts of the fruit epicarp and leaf were cytotoxic against the cell lines. Half-maximal inhibitory concentration (IC50) values for the 48 h cytotoxicity of the ethanol extract of the epicarp against HeLa and MRC5-SV2 cells were 48.0 μg/mL ± 12.1 μg/mL and 40.4 μg/mL ± 7.2 μg/mL, respectively, while fractions from second-level partitioning of the hexane fraction of the leaf extract elicited cytotoxicity with IC50 values ranging from 12.8 μg/mL ± 1.0 μg/mL to 39.6 μg/mL ± 7.2 μg/mL in both cell lines, following 48 h treatment. GC-MS revealed the presence of seventeen compounds in a hexane fraction of the leaf extract, including even- and odd-chain fatty acids, the most abundant of which were n-hexadecanoic acid, decanoic acid 10-(2-hexylcyclopropyl); and octadecanoic acid. The mechanisms of cytotoxicity of most active fractions involved generation of ROS and mitochondrial membrane depolarisation. Conclusions: The findings show that C. rostrata is rich in cytotoxic phytochemicals which could be isolated for developing new anti-cancer agents.
Sistem informasi dan metode pengelolaan manufaktur order berbasis website dengan metode waterfall (Studi kasus PT. Aji)
Authors: Agustian Agustian , Sifa Fauziah  , Wahyu Hadikristanto
Published: December 2023

PT Aji adalah perusahaan yang bergerak dibidang manufaktur lampu untuk kendaraan roda empat, kendaraan roda dua, kendaraan agrikultural, dan alat berat. Dibalik berjalannya operasional perusahaan khususnya dalam pengelolaan Manufacturing order masih di lakukan secara manual lalu dikelola di Ms. Excel sehingga, perhitungan stok barang di Deprtement menyebabkan Lost Time serta tidak ada monitoring barang secara realtime. Sistem yang diusulkan ialah sistem informasi aplikasi berbasis web informasi pengelolaan Manufacturing order yang didalam nya terdapat fasilitas untuk mengisi Planning, pengeluaran barang, laporan dan mampu melakukan edit data, guna perbaikan kesalahan dalam proses peng-inputan. Penelitian bertujuan untuk mengembangkan sistem informasi pengelolaan manufacturing yang terintegrasi dengan Database. Metode Waterfall mengharuskan setiap tahapan dilakukan secara berurutan dan tidak boleh dilakukan secara bersamaan. Pada Penelitian ini juga menunjukkan bahwa model ini terkait dengan pengembangan perangkat lunak yang sistematis, karena prosesnya berlangsung secara berurutan dan mengurangi risiko kesalahan dalam pembuatan sistem informasi tersebut. Pemrograman yang digunakan dalam hal ini adalah pemrograman website dengan menggunakan database MySQL dan bahasa pemrograman PHP (Hypertext Preprocessor). Dengan adanya sistem tersebut dari hasil penelitian Pengujian User Acceptance Test (UAT) dapat mempermudah dalam mengelola planning Manufacturing Order, barang keluar dan laporan. Sehingga dapat menyajikan informasi pengelolaan Manufacturing order secara cepat dan akurat
Deteksi kanker payudara menggunakan artificial neurol network pada deep learning
Authors: Giga Razki Ardiansyah  , Musayyanah Musayyanah , Wega Aqvirandy  , M. Difa Farady  , Mia Nilam Cahya  , Tri Hadiono
Published: December 2023

Penyakit kanker payudara merupakan penyakit urutan pertama yang mematikan di Indonesia. Penyakit ini telah menyita perhatian Kementerian Kesehatan Republik Indonesia, sehingga dibutuhkan teknologi untuk mendeteksi kanker payudara lebih dini. Penanganan penyakit kanker payudara yang lebih cepat dapat menghindari kematian. Dengan adanya teknologi Artificial Intelligence (AI), yang meniru kinerja otak manusia, dapat dimanfaatkan sebagai solusi medis. Salah satu penerapannya adalah deteksi kanker payudara. Pendekatan AI pada artikel ini, adalah dengan Deep Learning (DL). DL dianggap memiliki tingkat akurasi dan prediksi yang tinggi, salah satu model DL adalah Artificial Neural Network (ANN) yang mampu melakukan pengolahan data numerik yang tidak terstruktur dan tidak membutuhkan data training yang besar, sehingga fenomena overfitting dapat dihindari. ANN diterapkan untuk mendeteksi penyakit kanker payudara dengan 301 data setelah proses pre-processing, yang terdiri dari jumlah pasien, umur, positive axilliray nodes, dan survival status. Akurasi dari prediksi ANN pada penyakit ini mempunyai nilai akurasi sebesar 100%.
Klasifikasi karir mahasiswa bidang web developer menggunakan algoritma naïve bayes
Authors: Sonia Wanda Mafriza  , Armansyah
Published: December 2023

Mengenyam pendidikan sebagai mahasiswa IT (Information and Technology), tidak selalu menjamin seorang individu untuk memahami potensi dirinya di bidang tersebut. Banyak dari mahasiswa IT yang bahkan ketika mencapai semester akhir perkuliahan tidak mengetahui arah karir yang harus ia tuju sebagai seorang yang berada di bidang IT karena tidak mengetahui potensi dirinya. Penelitian ini bertujuan untuk mengklasifikasikan mahasiswa IT, khususnya Program Studi Ilmu Komputer dan Sistem Informasi, Universitas Islam Negeri Sumatera Utara, yang berpotensi menjadi seorang Web Developer, pada bagian karir “Front-end Developer” atau “Back-end Developer” dengan menggunakan algoritma naïve bayes. Sebanyak 64 data terkait performa dan pemahaman mahasiswa di bidang Web Development digunakan sebagai model pembelajaran. Hasil pemodelan dengan Algoritma Naïve Bayes menunjukkan bahwa minat karir mahasiswa IT di UINSU lebih besar pada karir Back-end Developer dibanding pada bagian Front-end Developer dengan akurasi model sebesar 85%. Diharapkan dengan adanya penelitian ini, dapat menjadi pemicu mahasiswa IT di UINSU untuk memperdalam potensi yang dimiliki dan menentukan tujuan karir mereka pada karir Web Developer.
Possibilities of Molecular Genetic Testing of Tumor Tissue for Personalized Breast Cancer Treatment
Authors: Макарова Мария Владимировна , Немцова Марина Вячеславовна , Чекини Дженнет Ашировна , Черневский Денис Константинович , Косова Екатерина Валерьевна , Баранова Елена Евгеньевна , Сагайдак Олеся Владимировна , Криницына Анастасия Александровна , Беленикин Максим Сергеевич
Published: December 2023

Сегодня результаты развития геномных технологий меняют подход к диагностике и лечению онкологических заболеваний. Так, клинические подходы к профилактике, диагностике и лечению рака молочной железы сместились в сторону использования молекулярно-генетической и иммуногистохимической информации.
Целью настоящего обзора является описание возможностей применения различных молекулярно-генетических исследований опухолевой ткани с целью повышения эффективности лечения рака молочной железы. В обзоре обсуждаются результаты применения современных молекулярных (The Cancer Genome Atlas) и иммуногистохимических (суррогатных) маркеров, обеспечивающих разделение РМЖ по молекулярным подтипам, приведены преимущества и недостатки такого разделения. Представлены основные характеристики современных экспрессионных прогностических тестов, обсуждается целесообразность и сложности применения высокопроизводительного секвенирования, в том числе расширенных мультигенных NGS-панелей  в клинической практике. Обзор предназначен для ординаторов и аспирантов, врачей-генетиков и врачей-онкологов, использующих в своей работе результаты современных молекулярно-генетических тестов.
Superselective Chemoembolization in a Personalized Approach to the Combined Treatment of Nasopharyngeal Cancer (Clinical Case)
Authors: Шайхов Мадани Магомедович , Раджабов Саидахмед Джабраилович , Воронов Виктор Григорьевич , Иванов Аркадий Александрович , Мансуров Ахмед Саипович , Митрофанов Александр Сергеевич , Раджабова Мадина Абдурахмановна , Пономарева Ольга Игоревна , Гиршович Михаил Марквович , Раджабова Замира Ахмед-Гаджиевна
Published: December 2023

Суперселективная химиоэмболизация (СХ) является на сегодняшний день перспективным методом лечения злокачественных новообразований органов головы и шеи. Описан клинический пример успешного комбинированного (СХ + системная химиотерапия) лечения злокачественного новообразования носоглотки у пациента 40 лет с двухсторонним распространением T4N2-3M0, приводящего к снижению слуха с двух сторон, существенному затруднению носового дыхания и осложненного носовыми кровотечениями. Достигнуто значительное улучшение качества жизни пациента.