bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Service Quality and Passenger Satisfaction Towards Electric Train Services (ETS): A PLS-SEM Approach
Authors: Mat Azmi , Bahry Norliza Saiful , Kori Nur Liana , Munir Zarina Abdul , Daud Norzaidi Mohd
Published: May 2019

This research is about service quality (responsiveness, reliability, tangible, safety and security) dimensions becoming major determinants of passenger satisfaction towards Electric Train Services (ETS). The significance of this study is intended to assist Keretapi Tanah Melayu Berhad (KTMB) to establish the service offered and to identify the important aspects of service quality that affect passenger satisfaction. A total of 280 questionnaires were distributed to ETS passengers, who were using the service from Kuala Lumpur Sentral Station to Padang Besar Station. The main objective of this study was to investigate the relationship between service quality dimensions and passenger satisfaction towards ETS. Data gathered were analyzed using partial least square (PLS) method. The study concluded that service quality dimensions are the factors affecting the passenger satisfaction towards ETS. In addition, service quality can also define the significant relationship between passenger satisfaction towards ETS. Other than that, several useful recommendations were made regarding the findings of this study.
Prevalence and intensity of Cornudiscoides agarwali (Monogenoidea) on the gills of Day’s mystus (Mystus bleekeri) in relation to some ecological and biological factors from Arunachal Pradesh, India
Authors: Tripathi A. , Wangchu L. , Trivedi A. K.
Published: May 2019

This work investigated the relationship of host size, seasons, and water quality parameters with the prevalence and intensity of Cornudiscoides agarwali on Mystus bleekeri collected from the Dikrong River in Arunachal Pradesh, India from February 2016 to January 2017. A total of 2760 specimens of C. agarwali were recovered from 114 individuals of M. bleekeri. The levels of mean intensity, but not the prevalence, of infection of C. agarwali were positively correlated with fish host size, peaking in the largest size class (45.20 ± 5.69 parasites/fish). The prevalence values had a statistically significant seasonal trend, reaching highest (100 %) during the pre-monsoon season, followed by 91.8% during the post-monsoon period and 87.5 % during the monsoon season. The levels of mean intensity of infection were also dependent on the seasons, reaching significantly higher levels during the pre-monsoon season (42.75 ± 4.18 parasites/fish). All water quality parameters measured were within the safety value recommended for freshwater aquaculture. Cornudiscoides agarwali maintained its prevalence above 87.5 % throughout the annual cycle, which means it was able to reproduce year-round in a non-polluted river. This could be an indication of monogenoidean community and population dynamics thriving best under optimum water quality parameters. Also, this article draws the attention of parasitologists and ichthyologists to a taxonomic problem of the misidentification of Mystus spp., and therefore, possibly of their parasitic monogenoids.
Evaluation of Potential Reservoir Deficiency Due to Climate Change, Kesem Kebena Dam, Ethiopia
Authors: Shumie Melese Chanie
Published: May 2019

Flood is an excess inundation of water on a surface and difficult to manage. The flood occurred in previous decades of Afar region of Ethiopia, consequently, leads to the death of human beings, destruction of infrastructures, an annihilation of massive hydraulic structures, and downstream properties. The main responsible factors for the flood incidences of the region are climate change, global warming, deforestation, and desertification. Climate change, however, is the foremost reason of increasing flood hazard. To coincide with this, hydraulic structures are designed based on the previously recorded flow data of a river. In Ethiopia, numerous earthen dams are constructed. The water storage capacity of dams is determined by the appraised flood of the upstream catchment: however, when the catchment flood increases due to climate extremes, the constructed structures cannot carry and going to demolish. The extra water that rises due to climate change from the catchment has to be removed before joins to the reservoir. This study has evaluated the potential reservoir deficiency of Kesem Kebena dam due to climate change. The study has comprehended different methods based on scientific criteria and selects the appropriate measure. As per the research output, the excess water that will arise from the catchment and add to the reservoir can be controlled by diversion floodways (Emergency spillways). The study has determined the amount of excess flood join to the reservoir for the excess rainfall incident month (August) for 100 years return period. Its magnitude is 85.76m3/s. The emergency spillway is the best means to divert such unwanted water before joining to the reservoir. Its hydraulic design is discussed in the study.
Significance of cyclooxygenase-2 in oncogenesis
Authors: Szweda Marta , Rychlik Andrzej , Babińska Izabella , Pomianowski Andrzej
Published: May 2019

The cyclooxygenase-2 (COX-2) enzyme catalyses the first stage of biosynthesis of prostanoids, proteins that are implicated in various physiological and pathological processes in humans and animals. The expression of COX-2 increases significantly during pathological processes accompanied by inflammation, pain and fever. Overexpression of COX-2 was determined in tumour tissues, which suggests that this enzyme participates in oncogenesis. In this paper the topics discussed are mechanisms regulating COX-2 expression, COX isoforms, their role in the body and the oncogenic mechanisms triggered by the overexpression of COX-2, including inhibition of apoptosis, intensification of neoangiogenesis, increased metastatic capacity, and weakening of the immune system. The significance of and the mechanisms by which COX-2 participates in oncogenesis have been studied intensively in recent years. The results are highly promising, and they expand our understanding of the complex processes and changes at the molecular, cellular and tissue level that promote oncogenesis and cancer progression. Notwithstanding the knowledge already gleaned, many processes and mechanisms have not yet been elucidated in human medicine and, in particular, in veterinary medicine. Further research is required to develop effective tumour diagnostic methods and treatment procedures for humans and animals.
Comparison of systemic effects of midazolam, ketamine, and isoflurane anaesthesia in rabbits
Authors: Atalan Güneri , Atalan Gültekin , Erol Hanifi , Erol Muharrem , Atasever Ayhan , Doğan Zafer , Güneş Vehbi , Yönez M. Kaan , Keleş Ihsan
Published: May 2019

Introduction: Clinical doses of anaesthetic agents were administered to rabbits and effects on the brain, heart, and liver were investigated biochemically and histopathologically. Material and Methods: The rabbits were randomly divided into three main groups (16 rabbits each) and each group into study (n = 8) and control (n = 8) groups. All study group rabbits received 3 mg/kg of midazolam (M) intramuscularly. Group 1.1 (M) received nothing further, group 2.1 (MK) also received 25 mg/kg of ketamine, and group 3.1 (MKI) besides ketamine was also given 2% isoflurane to induce anaesthesia for 30 min. NaCl solution in the same volume as midazolam and ketamine was injected into the controls. Results: In clinical evaluation significant differences were detected in respiratory and heart rates. In blood gas analysis the PO2 and PCO2 values showed statistical differences in anaesthesia intervals. Significant biochemical value changes were recorded in creatine kinase-Mb, glucose, and total protein. Histopathological liver examinations revealed higher total apoptotic and normal cell numbers in the MK than in the M and MKI groups. Apoptotic cell numbers were statistically significant in M and MK groups. Conclusion: Anaesthetic agents may increase programmed apoptosis. The MKI anaesthetics combination was found to cause less cell destruction in general than the other study groups. It was indicated that MKI was the safer anaesthetic combination in rabbits.
Productive perils: on metaphor as a theory-building device
Authors: Rodríguez H Claudio J
Published: May 2019

Metaphors constitute a relevant method for both building and making sense of theories. Semiotics is not exempt from their influence, and an important range of semiotic theories depends on metaphors to be meaningful. In this paper, we wish to examine the place of theory-constitutive metaphors considering the interaction view and the extent to which some areas of semiotics, particularly, the semiotics of culture and biosemiotics, are enriched by having metaphors dominate the way we think about them. The intention of the paper is not to document the different metaphors that have built semiotic theory, but rather to observe through a number of examples that semiotic research contains theory-building metaphors and that these are productive means of developing semiotic thinking further, with the caveat that theory change can be unexpected based on how we build metaphors for our theories.
The Combined Relative Uncertainty of Measurement Results by Prototype Semi-Automated Calorimetric Chamber
Authors: Kušnerová Milena , Valíček Jan , Harničárová Marta , Kmec Jan , Řepka Michal , Danel Roman , Panda Anton , Palková Zuzana
Published: May 2019

The paper presents an evaluation of the combined relative uncertainty of the result of direct step temperature measurements aimed at evaluation of the indirect measurements of the specific thermal capacity of the heat insulating concrete by means of a pair of resistive cable thermometers fitted with Pt100 temperature sensors and integrated into a computer-controlled calorimetric chamber. In particular, it is a proposal of evaluation of the overall relative uncertainty of the measurement of partial temperatures measured in equidistant time steps, in a relatively wider time interval. In practice, the uncertainty of the result of step temperature measurements is most often declared only by the instrument uncertainty specified by the manufacturer. The exact evaluation of the result of the measurements of thermal and temperature material parameters measured by the calorimetric comparison method is required by the fact that the investigated samples are made of newly designed non-tabulated building materials and that the measurements are made by a prototype device.
Design and simulation of high purity biodiesel reactive distillation process
Authors: Ali Syed Sadiq , Asif Mohammad , Basu Avijit
Published: May 2019

Biodiesel is a promising energy substitute of fossil fuels since it is produced from renewable and biodegradable sources. In the present work, reactive distillation (RD) process is designed and simulated using Aspen Plus process simulator to produce biodiesel of high purity through esterification reaction. The simultaneous reaction and separation in same unit enhances the biodiesel yield and composition in RD process. Two flowsheets are proposed in present work. In the first flowsheet, the unreacted methanol is recycled back to reactive distillation column. Biodiesel with 99.5 mol% purity is obtained in product stream while the byproduct stream comprises 95.2 mol% water, which has to be treated further. In the second flowsheet, a part of methanol recycle is split and purged. In this case, the biodiesel composition in product stream is 99.7 mol% whereas water composition is 99.9 mol% in byproduct stream, which can be reused for other process without treatment.
Together or Alone: The Price of Privacy in Collaborative Learning
Authors: Pejó Balázs , Tang Qiang , Biczók Gergely
Published: May 2019

Machine learning algorithms have reached mainstream status and are widely deployed in many applications. The accuracy of such algorithms depends significantly on the size of the underlying training dataset; in reality a small or medium sized organization often does not have the necessary data to train a reasonably accurate model. For such organizations, a realistic solution is to train their machine learning models based on their joint dataset (which is a union of the individual ones). Unfortunately, privacy concerns prevent them from straightforwardly doing so. While a number of privacy-preserving solutions exist for collaborating organizations to securely aggregate the parameters in the process of training the models, we are not aware of any work that provides a rational framework for the participants to precisely balance the privacy loss and accuracy gain in their collaboration.

In this paper, by focusing on a two-player setting, we model the collaborative training process as a two-player game where each player aims to achieve higher accuracy while preserving the privacy of its own dataset. We introduce the notion of Price of Privacy, a novel approach for measuring the impact of privacy protection on the accuracy in the proposed framework. Furthermore, we develop a game-theoretical model for different player types, and then either find or prove the existence of a Nash Equilibrium with regard to the strength of privacy protection for each player. Using recommendation systems as our main use case, we demonstrate how two players can make practical use of the proposed theoretical framework, including setting up the parameters and approximating the non-trivial Nash Equilibrium.
MorphIT: Morphing Packet Reports for Internet Transparency
Authors: Fragkouli Georgia , Argyraki Katerina , Ford Bryan
Published: May 2019

Can we improve Internet transparency without worsening user anonymity? For a long time, researchers have been proposing transparency systems, where traffic reports produced at strategic network points help assess network behavior and verify service-level agreements or neutrality compliance. However, such reports necessarily reveal when certain traffic appeared at a certain network point, and this information could, in principle, be used to compromise low-latency anonymity networks like Tor. In this paper, we examine whether more Internet transparency necessarily means less anonymity. We start from the information that a basic transparency solution would publish about a network and study how that would impact the anonymity of the network’s users. Then we study how to change, in real time, the time granularity of traffic reports in order to preserve both user anonymity and report utility. We evaluate with real and synthetic data and show that our algorithm can offer a good anonymity/utility balance, even in adversarial scenarios where aggregates consist of very few flows.
On Privacy Notions in Anonymous Communication
Authors: Kuhn Christiane , Beck Martin , Schiffner Stefan , Jorswieck Eduard , Strufe Thorsten
Published: May 2019

Many anonymous communication networks (ACNs) with different privacy goals have been developed. Still, there are no accepted formal definitions of privacy goals, and ACNs often define their goals ad hoc. However, the formal definition of privacy goals benefits the understanding and comparison of different flavors of privacy and, as a result, the improvement of ACNs. In this paper, we work towards defining and comparing privacy goals by formalizing them as privacy notions and identifying their building blocks. For any pair of notions we prove whether one is strictly stronger, and, if so, which. Hence, we are able to present a complete hierarchy. Using this rigorous comparison between notions, we revise inconsistencies between the existing works and improve the understanding of privacy goals.
DPSelect: A Differential Privacy Based Guard Relay Selection Algorithm for Tor
Authors: Hanley Hans , Sun Yixin , Wagh Sameer , Mittal Prateek
Published: May 2019

Recent work has shown that Tor is vulnerable to attacks that manipulate inter-domain routing to compromise user privacy. Proposed solutions such as Counter-RAPTOR [29] attempt to ameliorate this issue by favoring Tor entry relays that have high resilience to these attacks. However, because these defenses bias Tor path selection on the identity of the client, they invariably leak probabilistic information about client identities. In this work, we make the following contributions. First, we identify a novel means to quantify privacy leakage in guard selection algorithms using the metric of Max-Divergence. Max-Divergence ensures that probabilistic privacy loss is within strict bounds while also providing composability over time. Second, we utilize Max-Divergence and multiple notions of entropy to understand privacy loss in the worst-case for Counter-RAPTOR. Our worst-case analysis provides a fresh perspective to the field, as prior work such as Counter-RAPTOR only analyzed average case-privacy loss. Third, we propose modifications to Counter-RAPTOR that incorporate worst-case Max-Divergence in its design. Specifically, we utilize the exponential mechanism (a mechanism for differential privacy) to guarantee a worst-case bound on Max-Divergence/privacy loss. For the quality function used in the exponential mechanism, we show that a Monte-Carlo sampling-based method for stochastic optimization can be used to improve multi-dimensional trade-offs between security, privacy, and performance. Finally, we demonstrate that compared to Counter-RAPTOR, our approach achieves an 83% decrease in Max-Divergence after one guard selection and a 245% increase in worst-case Shannon entropy after 5 guard selections. Notably, experimental evaluations using the Shadow emulator shows that our approach provides these privacy benefits with minimal impact on system performance.
SoK: Modular and Efficient Private Decision Tree Evaluation
Authors: Kiss Ágnes , Naderpour Masoud , Liu Jian , Asokan N. , Schneider Thomas
Published: May 2019

Decision trees and random forests are widely used classifiers in machine learning. Service providers often host classification models in a cloud service and provide an interface for clients to use the model remotely. While the model is sensitive information of the server, the input query and prediction results are sensitive information of the client. This motivates the need for private decision tree evaluation, where the service provider does not learn the client’s input and the client does not learn the model except for its size and the result.

In this work, we identify the three phases of private decision tree evaluation protocols: feature selection, comparison, and path evaluation. We systematize constant-round protocols for each of these phases to identify the best available instantiations using the two main paradigms for secure computation: garbling techniques and homomorphic encryption. There is a natural tradeoff between runtime and communication considering these two paradigms: garbling techniques use fast symmetric-key operations but require a large amount of communication, while homomorphic encryption is computationally heavy but requires little communication. Our contributions are as follows: Firstly, we systematically review and analyse state-of-the-art protocols for the three phases of private decision tree evaluation. Our methodology allows us to identify novel combinations of these protocols that provide better tradeoffs than existing protocols. Thereafter, we empirically evaluate all combinations of these protocols by providing communication and runtime measures, and provide recommendations based on the identified concrete tradeoffs.
Prevalence of Hypoglycemia, Treatment Satisfaction, Adherence and Their Associations with Glycemic Goals in Patients with Type 2 Diabetes Mellitus Treated with Sulfonylureas: Findings from the Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) in Romania
Authors: Popoviciu Simona , Alionescu Anca , Sisic Irma
Published: May 2019

Background and aims: The aim of this study was to assess the prevalence and evaluate the impact on several treatment and quality of life parameters of hypoglycemia in type 2 diabetes mellitus patients treated with sulfonylureas (SU) in Romania. Secondary objective was to determine the proportion of patients attaining haemoglobin A1c (HbA1c) target of <7%.

Material and method: This was a multi-center, observational study using retrospective clinical chart and laboratory parameters review, and a cross-sectional survey in Romania. The sample in this study consisted of 385 patients. Socio-demographic and clinical variables were compared between patients with inadequate and adequate control.

Results: The mean age of all enrolled subjects was 65.37 (33-87) years. The average BMI was 30.44 kg/m2. Mean diabetes duration was 7.76 (6 months -32) years with the mean age of diabetes at diagnosis of 57.75 (31-85) years. HbA1c was recorded for 238 subjects with mean value of 7.12 (4.8-10.97) %.

Conclusions: The prevalence of hypoglycaemia in SU treated patients was 42.2%. Highest prevalence was in the 50-60 age category, at 49.2% and lowest among the eldest subjects (>70 years), at 38.6%. Prevalence of patients at the goal of HbA1c<7% was 50.8 %. Patients with adequate glycaemic control had more acceptable BMI than those with inadequate glycaemic control. In patients not achieving a goal of HbA1c < 7%, higher level of plasma glucose and total cholesterol was determined compared to those with adequate glycaemic control. There were no significant differences in the HDL-C, triglycerides or albumin:creatinine ratios in patients with both adequate and inadequate glycaemic control.
Whiplash Syndrome
Authors: Sarafoleanu Dorin , Enache Raluca
Published: May 2019

Whiplash syndrome is a quite common pathology and can be defined as a neck injury produced by a sudden acceleration-deceleration, the consequence of which is a sudden forward and backward movement of the head and neck. The main production mechanism is a sudden acceleration-deceleration process that has as a consequence the sudden extension/flexion of the neck. Starting from the many structures involved, the whiplash syndrome is an interdisciplinary challenge (ENT specialist, neurologist, orthopedist, ophthalmologist, psychologist) and can be described by multiple signs and symptoms.

Whiplash syndrome is a complex pathology both through the mechanism of production and symptoms, and through the forensic implications that it has. The interdisciplinary medical collaboration, the implementation of stricter rules on wearing the seat belt and the development by car manufacturers of chairs and head restraints that protect the head and neck of passengers, would be the preventive step in the occurrence and especially the chronicization of these lesions.
Prevalence of a Iodothyronine Deiodinase 2 gene single nucleotide polymorphism in children with congenital hypothyroidism from Western Romania and impact on TSH levels
Authors: Mang Niculina , Tămas Liviu Athos , Mărginean Otilia , Marian Cătălin , Ursoniu Sorin , Anghel Andrei
Published: May 2019

The aim of this study was to evaluate the prevalence of the Iodothyronine Deiodinase 2 gene Thr92Ala polymorphism in children from West of Romania with congenital hypothyroidism (CH) and association with TSH levels in response to levothyroxine monotherapy.

Genotyping in 50 children with CH and 52 healthy controls was done using real time PCR.

The results showed that there was no statistical difference between the frequencies of genotypes in patients vs. controls. Patients were treated with L-thyroxine and most had normal values for fT3 and fT4. However, high TSH values were found in 21 patients (42%) after treatment. Among patients with high TSH values, AA genotypes were significantly more prevalent (p = 0.044) than TT and AT genotypes. Our results suggest that for the D2 gene Ala92Thr polymorphism, the AA genotype may be detrimental for achieving euthyroidism in patients with CH and levothyroxine monotherapy, therefore polytherapy could be considered as a better approach in these patients.
Is there any association between Serum anti-HSP27 antibody level and the presence of metabolic syndrome; population based case-control study
Authors: Sadabadi Fatemeh , Heidari-Bakavoli Alireza , Esmaily Habibollah , Darroudi Susan , Tayefi Maryam , Asadi Zahra , Parizadeh Seyed Mohammad Reza , Tavalaie Shima , malekzadeh Najmeh , Moghaddam Kiana Hosseinpour , Moghadam Azam Rastgar , Sahebkar Amir Hosein , Fereydouni Narges , Barati Elham , Azarpazhooh Mahmoudreza , Hosseini Seyyed Javad , Tayyebi Mohammad , Ebrahimi Mahmoud , Ferns Gordon A. , Ghayour-Mobarhan Majid , Mouhebati Mohsen
Published: May 2019

Background: Heat shock protein 27 (HSP27) is an intracellular chaperone constitutively expressed in many cell types including cardio myocytes and endothelial cells. Circulating levels of HSP27 and anti-HSP27 antibody are higher in patients with CVD. Anti-HSP27 antibody concentrations were also reported to be increased in atherogenesis. We aimed to evaluate serum anti-HSP27 antibody titers in individuals with, or without, MetS in the MASHAD study cohort with large sample size in 6,568 subjects.

Methods: Participants with MetS were identified from MASHAD cohort (n=3358) using the IDF criteria, and the control group were those individuals who did not meet these criteria (n=3210). In-house enzyme-linked immune sorbent assay (ELISA) method was used for measuring Anti-HSP27 antibody levels. The two groups were matched for age, sex and smoking habit.

Results: As expected, there were significant differences in height (p= 0.004), waist and hip circumference, weight, BMI, systolic and diastolic blood pressure, TGs, TC, HDL-C, Hs-CRP, glucose, with the presence of diabetes mellitus, hypertension, hyperlipidemia (p<0.001) between the two groups. Serum HSP27 antibody titers did not show significant difference between the groups with and without metabolic syndrome (p= 0.740).

Conclusion: In conclusion, our results revealed serum anti-HSP27 antibody titers were not statistically different between individuals with and without MetS. However, it is possible that drug treatment may affect antibody titers and confound our findings in this population sample..
Reference interval and upper decission limit for serum uric acid – an evidence-based approach on Romanian population using an a posteriori method
Authors: Codreanu Catalin , Popoviciu Horatiu , Rezus Elena , Mogosan Corina Delia , Gardikiotis Ioannis , Popescu Claudiu Costinel
Published: May 2019

Introduction. There is accumulating evidence that high normal serum uric acid (SUA) levels of 6-7 mg/dL are associated with cardiovascular morbidity and metabolic syndrome (MetS), hence the need to redefine its upper limit of normal (ULN). We aimed to derive ULN based on statistics and evidence in a representative sample of the population and to observe its relation to MetS components.

Methods. All SUA measurements form a university rheumatology hospital were extracted between January 5th 2010 and March 21st 2018. SUA levels were measured by a single biochemist a unique type of commercially available kit. Follow-up measurements, patients with diagnoses influencing SUA levels and outlying measurements were excluded. ULNs were studied using least square analysis.

Results. Of the 22503 SUA measurements in the database, only 3318 came from normal individuals: 33.3% men (n=1105), 66.7% women (n = 2213). Least square analysis revealed the following SUA reference intervals (RI): 3.43-6.19 mg/dL for the combined sample; 4.44-7.01 mg/dL for men, 3.28-5.56 mg/dL for women. The values corresponding to the 66th percentile of each group presented lower ULNs: 5.36 mg/dL for all, 6.10 mg/dL for men, 4.90 mg/dL for women. The prevalence of hyperuricemia increased from 13.8% (manufacturer’s gender-specific ULN) to 19.9% (derived ULN). Mean SUA levels significantly increased with the number of MetS components.

Conclusion. We recommend that hyperuricemia should be defined using a statistical approach of ULN selection corresponding to the genderand population-specific 66th percentile of data range.
Emergence of rotavirus G9 in 2012, as the dominant genotype in Turkish children with diarrhea, in a university hospital in Ankara
Authors: Koçak Aylin Altay , Aydın Merve , Matsumoto Takashi , Yahiro Takaaki , Dalgıç Buket , Bozdayi Gulendam , Ahmed Kamruddin
Published: May 2019

Introduction: Rotavirus infection is a major cause of morbidity and mortality in infants and young children with diarrhea throughout the world.

Material and Methods: In this study, we aimed to determine the detection rate of rotavirus infection in 181 children less than 5 years of age presenting with acute gastroenteritis and admitted to a tertiary care hospital in Ankara, Turkey, from April to November 2012. We documented the epidemiological data by elucidating the prevalent genotypes. Stool specimens were collected, and rotavirus antigen in the samples was detected using ELISA. G and P genotypes were determined by RT-PCR via type specific primers. The nucleotide sequence of the concerned genes was determined by Sanger sequencing and phylogenetic analysis was performed by neighbor-joining method.

Results: Of the 181 samples, 28 (15.5%) were positive for the rotavirus antigen. Twenty-seven samples were positive for G genotypes and 21 were positive for P genotypes. Genotypes G1 (7.1%), G2 (7.1%), G3 (7.1%), G4 (3.6%), G9 (71.5%) and P4 (3.6%), P8 (71.4%) were identified. Genotype G9P[8] (50%) was predominant in the combination of G and P genotypes. Most of the G9 strains of this study formed an independent cluster in Lineage III, except two strains which clustered with an Ethiopian G9 strain of 2012.

Conclusions: It seems that during 2012 season, genotype G9P[8] increased significantly in Ankara due to a new circulating strain of G9.
Studi Potensi Kawasan Subak Sebagai Ekowisata di Desa Belimbing Kecamatan Pupuan Kabupaten Tabanan
Authors: INDRAYUNI DEWA AYU BULAN , KOHDRATA NANIEK , SUKEWIJAYA I MADE
Published: May 2019

ABSTRACT

Potential Study of Subak Area for Ecotourism in Belimbing Village, Pupuan District, Tabanan Regency

Tabanan regency is the highest rice producing regency in Bali. The suvvess in agricultural production is inseparable from Subak organization existency. This past few years, Tabanan experiencing an increase land conversion. It becomes a threat to the existence of Subak. Developing ecotourism in Subak area is an effort to reduce numbers of land conversion and Subak degradation. Belimbing village has a potential to be developed as ecotourism. The potential identification in Subak area of the village shows there are some Subak values as well as environment potentials that can be developed as area for ecotourism. The beautiful landscape of rice field terrace, Tri Hita Karana (THK) based agricultural and local community social cultured activities are potential for tourist attraction. However, there is a need to educate the local people in order to support the implementation of ecotourism in Subak area of Belimbing village. By developing Subak area as ecotourism, it is expected to improve the welfare of the local people, especially former and Subak organization also preserve the environment as well.

Keywords: ecotourism, identification of potential, subak areas
Perencanaan Bumi Perkemahan Alun-Alun Suryakencana Taman Nasional Gunung Gede Pangrango, Jawa Barat
Authors: Muttaqin Imam , Semarajaya Cokorda Gede Alit , Yusiana Lury Sevita
Published: May 2019

Camping ground planning of Alun-alun Suryakencana in Mt. Gede Pangrango National Park, West Java. A good campsite requires a plan. Planning is done zoning area that can be used as a camping area without disturbing the existing ecosystem and equipped facilities so that users can feel comfortable while in the area of the campground. Alun-alun Suryakencana at an altitude of 2750 m asl is part of the Mount Gede Pangrango National Park of West Java. This research was conducted in October 2016-August 2017, this research method refers to Rachman's (1984) complete thinking process in Norma (2013) which applies secondary data analysis at field study stage which consists of inventory, analysis, synthesis, concept, and planning. The final result of this planning is a Campsite Plan that is implemented in Alun-alun Suryakencana.
Konsep bentuk kujang sebagai salah satu identitas eksistensi budaya Sunda dalam perencanaan taman di Kota Bogor
Authors: Radnawati Daisy , Febriani Yusi , Nurhayati Eli
Published: May 2019

Kujang form concept as an identity of Sundanese culture existence in Bogor urban park planning. City Park is a public space where people gather and do various activities in it. There are several functions of urban parks such as community associations, sports venues, environmental education, health promotion and aesthetic value. Some of the city parks in Bogor are Malabar Park, and Empang Park which is surrounded by residential areas and is mainly used as a sports vessel. Contrary to its function, the activity has not been supported by facilities that can provide user comfort and security. The problems seen in the existing condition of the park in Bogor are generally very bad and unkempt, some of the park has no recreational facilities or other supporting facilities that can be used by the public, has no strong character or identity, and has not connected between parks (connecting park). Researchers collect data through direct observation at the research site. Researchers looked at the entire site including physical aspects (accessibility, entrance, circulation path, road dimension, climatology), biophysical (vegetation and wildlife) aspects, and socio-cultural aspects (park visitor behavior). Observations are used by researchers as additional information in the study. Field survey in this research can be obtained by observation, interview and documentation. The concept of connecting park is applied to provide connectivity between parks that have an identity and can present the elements and appropriate park facilities so as to provide satisfaction, pleasure, comfort, and security to the user. Kujang as traditional weapon of Sundanese applied as the form and design concept of the parks.
Pengaruh komposisi media tanam terhadap pertumbuhan rumput gajah mini variegata (Axonopus compressus)
Authors: Sinaga Putra Diangga , Ruliyansyah Agus , Pramulya Muhammad
Published: May 2019

Effect of the composition of planting media on the growth of pearl grass variagated (Axonopus Compresuss). Pearl grass variagated (Axonopus compresuss), is a kind of ornamental grass used as landscape grass or carpet grass. Planting pearl grass variegated at this time, just plowing land, only ultisol. These conditions cause the growth of slow grass, easy soil erosion, then it takes quite a long time to cover the land. Because Ultisol is poor for nutrients and has a solid soil structure, it requires a mixture of organic composition to add nutrients and improve soil structure to loose. Therefore Organic materials used such as sawdust and cow dung manure. The objective of the research is knowing the composition of planting media consists of, Ultisol (PMK), sawdust (SG) and cow‘s manure (KS) on planting of pearl grass variegated. Planting is done on the map with size 0.5 m x 0.5 m. This research used Completely Randomized Design () with 6 treatments, 5 replicates, each replication consist 25 plant and sampling 20%. Treatment for compositions such as m0 (PMK 100%), m1 (PMK 75%: SG 25%), m2 (PMK 75%: PS 25%), m3 (PMK 50%: SG50%), m4 (PMK 50%: PS 50%), m5 (PMK 50%, PS 25%, SG 25%). The research was done for approximately 3 months from mid August to November 2017 in experimental garden Faculty of Agriculture UNTAN. The Research shows that the composition of planting media have significant effect on observation variables, such as number of tillers, stolon length, cover area, root length and dry weight. The result of this research shows, the treatmen of m4(PMK 50% : PS 50%) has higher value among of other treatment.
Tata letak tanaman pada rumah berkonsep arsitektur tradisional Bali di Kota Bangli, Kabupaten Bangli Provinsi Bali
Authors: Pranditha I Dewa Gede Agung Surya , Sugiantara Anak Agung Gede , Pradnyawathi Ni Luh Made
Published: May 2019

The plants layout on Balinese traditional architecture concept houses in Bangli City, Bangli Regency, Bali Province. Bangli Regency is one of the regency that located in the central part of Bali island and only one of regency do not have sea. Balinese Traditional Architecture can be interpreted as the spatial from the life place of Balinese community that has developed through generations with all the rules are inherited from ancient times, until the development of a form with the physical characteristics are revealed on the Lontar Asta Kosala-Kosali. The traditional Balinese park is not only involved the architectural, functional, aesthetic, but also used Balinese cultural philosophy in every placement of it landscape components. The purpose of this research were to understand the effect of land to the application Balinese Traditional Architecture, to understand the concept are using on development house in the city of Bangli regency and then to know how the sense of Balinese traditional architecture on the houses in Bangli city, Bangli regency. The result of the study was that the land area is very influential on the implementation of Traditional Balinese Architecture because there are rules that should be applied that is Asta Kosala-Kosali, the concept applied is Tri Hita Karana, Tri Mandala dan Tri Angga. Plants layout on Balinese people’s knowing is very less, so in plant layouting people only accentuate the aesthetic without a Balinese cultural philosophy.
Studi desain Taman Tebet sebagai youth park
Authors: Putra Aprianto Dwi , Kohdrata Naniek , Gunadi I Gusti Alit
Published: May 2019

Design study of Taman Tebet as youth park. Jakarta’s green open spaces should have functional value to fulfill the need of heterogeneous people of Jakarta for open public spaces. The absence of character in most of Jakarta’s city parks is underpinning this research. This research’s objective is to illustrate the character of Jakarta’s city park by creating a design concept that fit with current Jakarta’s people needs. The research methods are inventory, analysis, synthesis, concept to design stage. The result of this research is a concept of design that can depict Jakarta city park character today, by applying contemporary landscape elements. The existing design concept will be complemented with design development to strengthen the characteristic of the park. The end products of this research are the design concept, concept of space, concept of circulation, the green layout concept, site plan, and transformation of certain object shape which will be specially displayed. As a conclusion, Youth Park design concept is able to bring a new characters in the park of Jakarta in general and can meet the needs of public space Jakarta now.
Persepsi dan preferensi masyarakat terhadap taman rekreasi bantaran Sungai Loloan Sanur
Authors: Pradipta I Gede Angga , Sarwadana Sang Made , Pradnyawathi Ni Luh Made
Published: May 2019

Public Perception and Preference of Loloan Riverbank Recreational Park Sanur. Denpasar is a developing city. Like other developing cities in Indonesia, Denpasar City continues to carry out development in various aspects, one of which is the construction of a recreational park. Servers as a recreational facility and social interaction for the people of Denpasar City. One of the recreational parks being promoted is Recreational Park of Loloan Riverbanks located in Sanur Village. To maximize functionality and improve quality of The Recreational Park Loloan Riverbanks, therefore should be done research on this Recreational Park Loloan Riverbanks to know how perception and preference the community as a user of recreational park. This research used survey method with data collection techniques is observation, interview and questionnaire wich amounted to 30 copies for 30 respondent. Result of people’s perceptions showed Recreational Park of Loloan Riverbanks serves as a cheap recreational place and a cheap sport venue for the people’s of Denpasar City. Result of people’s preference showed addition of recreational park support facilities will lead to increased levels of enjoyment and visitor satisfaction from the Recreational Park of Loloan Riverbank. Public perception and preference of The Recreational Park Loloan Riverbanks used as information and references to the manager or related parties that play a role in managing The Recreational Park Loloan Riverbanks Denpasar City, so that later The Recreational Park Loloan Riverbanks will be liked by the community of Denpasar City.
SENSIBILIZAÇÃO DA BLOMIA TROPICALIS EM PACIENTES ASMÁSTICOS EM SÃO LUÍS E REGIÕES METROPOLITANA
Authors: Brito Poliana Oliveira Lemos de , Duarte Thalita Diniz , Lima João Lucas do Carmo , Pereira Caroline Zilma Kalil de Paula Costa , Azevedo Camila Rodrigues , Pereira Maryangela Godinho , Falcai Angela
Published: May 2019

As doenças alérgicas podem causar comprometimento da qualidade de vida das crianças, no qual está exposto a uma série de alérgenos, que podem gerar uma resposta do sistema imunológico como reações de hipersensibilidade. O objetivo da pesquisa foi avaliar o perfil sócio-econômico e ambiental de crianças e adolescentes sensibilizados a Blomia tropicalis (Blo t) em São Luís e região metropolitana. Aprovada pelo comitê de ética e pesquisa, com o parecer de numero: 58737916.30000.5084. Foi realizado um estudo epidemiológico por meio de análise de prontuários em pacientes do Hospital da Criança de São Luís-MA, onde foram submetidos ao teste cutâneo para o alérgeno Blo t e aplicado o questionário ISSAC e complementar. Teste estatístico utilizado foi o Qi-quadrado- Fisher. A população estudada foi constituída por 87 crianças e adolescentes, entre idade de 1 a 17 anos. Na caracterização clínica destes pacientes foi observado uma associação entre a sensibilização o Blo t e a sensibilização ao Dermatophagoides pteronissynus, Dermatophagoides farinae, Periplaneta americana, Blatella germânica e ao cachorro. Observou-se também uma associação com baixa renda familiar, asma e eczema atópico. Quanto a caracterização ambiental observou-se uma correlação entre manchas na parede (mofo) e forro no quarto. Concluímos que a sensibilização o Blo t é um fator de risco para desenvolvimento de asma e eczema e esta relacionado com vários alérgenos, a baixa renda familiar e que o controle ambiental para blo t é essencial para diminuir a prevalência da asma e do eczema e para melhorar a qualidade vida.PALAVRAS-CHAVE: asma; alérgeno; hipersensibilidade
COMPARAÇÃO DA QUALIDADE DE VIDA DE INDIVÍDUOS COM E SEM HANSENÍASE
Authors: Torres Denise Carvalho , Pinho Kelyanne Dos Santos , Borges Claudio Karone da Silva , Lopes Anderson Batista , Costa Gabriel Pereira da , Gonçalves Maria Claudia , Carvalho Sarah Tarcísia Rebelo Ferreira de
Published: May 2019

A Hanseníase é uma doença infectocontagiosa crônica que provoca disfunções no sistema somatossensorial, deficiência física, distúrbios psicológicos e exclusão social, podendo comprometer a qualidade de vida. O presente estudo tem como objetivo comparar a qualidade de vida de indivíduos com o diagnóstico de hanseníase e sem histórico de hanseníase. Trata-se de um estudo analítico do tipo transversal, com 100 indivíduos maiores de 18 anos, de ambos os gêneros. Os indivíduos foram divididos em dois grupos: GH-com 50 pacientes com diagnóstico de hanseníase que estão em tratamento assistido e GC–com 50 indivíduos sem histórico de hanseníase. Foram coletadas informações sociodemógraficas e de qualidade de vida, através do questionário SF-36 (Medical Outcome Study-Mos Short From Health Survey). O estudo foi aprovado pelo Comitê de Ética em Pesquisa (Parecer Número: 1.674.308). Constatou-se que o GH e o GC eram homogêneos estatisticamente em relação à idade, sexo e IMC (p > 0,05), sendo a maioria adulta jovens, do sexo masculino e peso considerado normal. Quanto à qualidade de vida, constatou-se, que o GH apresentou todos os oitos domínios significativamente pior em relação ao GC (p<0,005). No GH, os domínios com escores mais baixos foram: aspectos físicos (escore=20,00); dor (escore=38,66); aspectos emocionais (escore =41,23) e; estado geral da saúde (escore=43,64). Considera-se que estes dados podem direcionar os profissionais de saúde envolvidos no tratamento de pacientes com hanseníase, no sentido de conscientizá-los de que esta doença envolve fatores físicos, psicológicos, mentais e sociais, devendo-se tratar não apenas os seus sintomas, mas os indivíduos integralmente.PALAVRAS-CHAVE: Hanseníase; Qualidade de vida; Saúde.
POTENCIAL ANTIOXIDANTE E ANTIBACTERIANO CONTRA CORYNEBACTERIUM ULCERANS DO ÓLEO ESSENCIAL DE CANELA
Authors: Viana Pamela Ruth Santos , Leite Denes Sousa , Guaraldi Ana Luíza de Mattos , Firmo Wellyson Da Cunha Araújo , Sabbadini Priscila Soares
Published: May 2019

Corynebacterium ulcerans é um patógeno emergente em vários países, inclusive no Brasil, e está envolvido em diversos quadros clínicos, incluindo a difteria. O estudo da atividade antibacteriana de óleos essenciais (OEs), extraídos de plantas de interesse farmacológico, na busca de um antimicrobiano ideal tem sido bastante difundido. O objetivo desta pesquisa foi avaliar o potencial antioxidante e a atividade antibacteriana do OE obtido da canela. A partir das folhas da planta, coletadas no município de São Luís-MA, extraiu-se o óleo por hidrodestilação por arraste a vapor. Para avaliação da ação antioxidante do OE em diferentes concentrações, utilizou-se o método de quelação do íon ferroso. A fim de determinar a atividade antibacteriana, testes de difusão (disco e poço) em ágar e de determinação das concentrações inibitória mínima (CIM) por microdiluição e bactericida mínima (CBM) foram realizados com seis isolados clínicos e uma amostra padrão de C. ulcerans. A capacidade do OE para quelar 50% do íon ferroso (CE50) foi de 464,3±0,1726 µg/mL. Nos testes de difusão em ágar, não foi observada a formação de halos de inibição bacteriana com as concentrações do OE utilizadas. Porém, foi possível determinar a CIM do OE para todas as amostras, sendo a menor de 3,90 µg/ml.  Não se encontrou a CBM com as concentrações avaliadas. O OE de canela demonstrou ação antioxidante e antibacteriana contra C. ulcerans, sugerindo seu potencial para uso terapêutico.PALAVRAS-CHAVE: corinebactérias; planta medicinal; antimicrobiano
Hemodynamic aspects of pulmonary and systemic bloodflow in patients with total anomalous pulmonary venous connection
Authors: Morozov A. A. , Movsesyan R. R.
Published: May 2019

This review is focused on the problem of the hemodynamics in patients with total anomalous pulmonary venous connection. The article describes a structural features of the pulmonary venous return depending on the anatomical type, pulmonary and systemic hemodynamics, origin and effect of the pulmonary venous return obstruction on the hemodynamics. We presented basic diagnostic problems and principles, including prenatal level, and discussed trends, results and unsolved questions of the surgical treatment of the patients with total anomalous pulmonary venous connection.