bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of central administration of the human Tau proteinon the Bdnf, Trkb, p75, Mapt, Bax and Bcl-2 genes expression in the mouse brain
Authors: Oreshko A. S. , Rodnyy A. Ya. , Bazovkina D. V. , Naumenko V. S.
Published: July 2023

Alzheimer’s disease is the most common form of dementia, affecting millions of people worldwide. Despite intensive work by many researchers, the mechanisms underlying Alzheimer’s disease development have not yet been elucidated. Recently, more studies have been directed to the investigation of the processes leading to the formation of neurofibrillary tangles consisting of hyperphosphorylated microtubule-associated Tau proteins. Pathological aggregation of this protein leads to the development of neurodegeneration associated with impaired neurogenesis and apoptosis. In the present study, the effects of central administration of aggregating human Tau protein on the expression of theBdnf, Ntrk2, Ngfr, Mapt, BaxandBcl-2genes in the brain of C57Bl/6J mice were explored. It was found that five days after administration of the protein into the fourth lateral ventricle, significant changes occurred in the expression of the genes involved in apoptosis and neurogenesis regulation, e. g., a notable decrease in the mRNA level of the gene encoding the most important neurotrophic factor BDNF (brain-derived neurotrophic factor) was observed in the frontal cortex which could play an important role in neurodegeneration caused by pathological Tau protein aggregation. Central administration of the Tau protein did not affect the expression of theNtrk2, Ngfr, Mapt, BaxandBcl-2genes in the frontal cortex and hippocampus. Concurrently, a significant decrease in the expression of theMaptgene encoding endogenous mouse Tau protein was found in the cerebellum. However, no changes in the level or phosphorylation of the endogenous Tau protein were observed. Thus, central administration of aggregating human Tau protein decreases the expression of theBdnfgene in the frontal cortex and theMaptgene encoding endogenous mouse Tau protein in the cerebellum of C57Bl/6J mice.
Comparison of the evolutionary patterns of DNA repeats in ancient and young invertebrate species flocks of Lake Baikal
Authors: Yuxiang Wang , Peretolchina T. E. , Romanova E. V. , Sherbakov D. Y.
Published: July 2023

DNA repeat composition of low coverage (0.1–0.5) genomic libraries of four amphipods species endemic to Lake Baikal (East Siberia) and four endemic gastropod species of the fam. Baicaliidae have been compared to each other. In order to do so, a neighbor joining tree was inferred for each quartet of species (amphipods and mollusks) based on the ratio of repeat classes shared in each pair of species. The topology of this tree was compared to the phylogenies inferred for the same species from the concatenated protein-coding mitochondrial nucleotide sequences. In all species analyzed, the fraction of DNA repeats involved circa half of the genome. In relatively more ancient amphipods (most recent common ancestor, MRCA, existed approximately sixty millions years ago), the most abundant were species-specific repeats, while in much younger Baicaliidae (MRCA equal to ca. three millions years) most of the DNA repeats were shared among all four species. If the presence/absence of a repeat is regarded as a separate independent trait, and the ratio of shared to total numbers of repeats in a species pair is used as the measure of distance, the topology of the NJ tree is the same as the quartet phylogeny inferred for the mitogenomes protein coding nucleotide sequences. Meanwhile, in each group of species, a substantial number of repeats were detected pointing to the possibility of non-neutral evolution or a horizontal transfer between species occupying the same biotope. These repeats were shared by non-sister groups while being absent in the sister genomes. On the other hand, in such cases some traits of ecological significance were also shared.
The role of Beringia in human adaptation to Arctic conditions based on results of genomic studies of modern and ancient populations
Authors: Malyarchuk B. A.
Published: July 2023

The results of studies in Quaternary geology, archeology, paleoanthropology and human genetics demonstrate that the ancestors of Native Americans arrived in mid-latitude North America mainly along the Pacific Northwest Coast, but had previously inhabited the Arctic and during the last glacial maximum were in a refugium in Beringia, a land bridge connecting Eurasia and North America. The gene pool of Native Americans is represented by unique haplogroups of mitochondrial DNA and the Y chromosome, the evolutionary age of which ranges from 13 to 22 thousand years. The results of a paleogenomic analysis also show that during the last glacial maximum Beringia was populated by human groups that had arisen as a result of interaction between the most ancient Upper Paleolithic populations of Northern Eurasia and newcomer groups from East Asia. Approximately 20 thousand years ago the Beringian populations began to form, and the duration of their existence in relative isolation is estimated at about 5 thousand years. Thus, the adaptation of the Beringians to the Arctic conditions could have taken several millennia. The adaptation of Amerindian ancestors to high latitudes and cold climates is supported by genomic data showing that adaptive genetic variants in Native Americans are associated with various metabolic pathways: melanin production processes in the skin, hair and eyes, the functioning of the cardiovascular system, energy metabolism and immune response characteristics. Meanwhile, the analysis of the existing hypotheses about the selection of some genetic variants in the Beringian ancestors of the Amerindians in connection with adaptation to the Arctic conditions (for example, in the FADS, ACTN3, EDAR genes) shows the ambiguity of the testing results, which may be due to the loss of some traces of the “Beringian” adaptation in the gene pools of modern Native Americans. The most optimal strategy for further research seems to be the search for adaptive variants using the analysis of paleogenomic data from the territory of Beringia, but such genetic data are still very scarce.
Clinical, genetic aspects and molecular pathogenesis of osteopetrosis
Authors: Nadyrshina D. D. , Khusainova R. I.
Published: July 2023

Osteopetrosis (“marble bone”, ICD-10-78.2) includes a group of hereditary bone disorders distinguished by clinical variability and genetic heterogeneity. The name “osteopetrosis” comes from the Greek language: ‘osteo’ means ‘bone’ and ‘petrosis’ means ‘stone’, which characterizes the main feature of the disease: increased bone density caused by imbalances in bone formation and remodeling, leading to structural changes in bone tissue, predisposition to fractures, skeletal deformities. These defects, in turn, affect other important organs and tissues, especially bone marrow and the nervous system. The disease can be autosomal recessive, autosomal dominant, X-linked or sporadic. Autosomal dominant osteopetrosis has an incidence of 1 in 20,000 newborns and autosomal recessive one has 1 in 250,000. To date, 23 genes have been described, structural changes in which lead to the development of osteopetrosis. Clinical symptoms in osteopetrosis vary greatly in their presentation and severity. The mildest skeletal abnormalities are observed in adulthood and occur in the autosomal dominant form of osteopetrosis. Severe forms, being autosomal recessive and manifesting in early childhood, are characterized by fractures, mental retardation, skin lesions, immune system disorders, renal tubular acidosis. Clinical examination and review of radiographs, bone biopsy and genetic testing provide the bases for clinical diagnosis. The early and accurate detection and treatment of the disease are important to prevent hematologic abnormalities and disease progression to irreversible neurologic consequences. Most patients die within the first decade due to secondary infections, bone marrow suppression and/or bleeding. This article summarizes the current state of the art in this field, including clinical and genetic aspects, and the molecular pathogenesis of the osteopetrosis.
Taxonomic and ecophysiological characteristics of actinobacteria in soils of the dry steppe zone of the Selenga Highlands (Western Transbaikalia)
Authors: Nikitina E. P. , Buyantueva L. B. , Abidueva E. Yu. , Sun C. H.
Published: July 2023

Arid habitats have recently attracted increasing attention in terms of biodiversity research and the disco very of new bacterial species. These habitats are among the target ecosystems suitable for isolating new strains of actinobacteria that are likely to produce new metabolites. This paper presents the results on the isolation of actinobacteria from soils of the dry steppe zone of the Selenga Highlands, the characterization of their taxonomic diversity, as well as ecological and trophic properties. The bacterial counts on ISP 4 medium ranged from 6.6 × 105 to 7.1 × 106 CFU/g. The highest bacterial counts were observed in the subsurface and middle horizons of the studied soils. 28 strains of Gram-positive bacteria represented by thin-branched mycelium, coccoid and bacilliform forms were isolated. According to the results of 16S rRNA gene analysis, the isolated strains were representatives of Streptomyces, Arthrobacter, Glycomyces, Kocuria, Microbacterium, Micromonospora, Nocardioides, Pseudarthrobacter, and Rhodococcus (Actinomycetota). One isolate that showed low 16S rRNA gene sequence similarity with previously isolated and validly described species was a new species of the genus Glycomyces. It was shown that all tested strains are mesophilic, prefer neutral or slightly alkaline conditions, have growth limits in the temperature range of 5–45 °C and pH 6–9. The optimal NaCl concentration for growth of most strains was 0–1 %. The strains under study were capable of utilizing a wide range of mono- and disaccharides and polyatomic alcohols as a carbon source. The isolated strains were capable of using both organic (proteins and amino acids) and inorganic (ammonium salts and nitrates) compounds as nitrogen sources. The examinations of extracellular enzymes showed that all isolates were capable of producing catalase and amylase; 78.6 % of the total number of isolates produced protease and lipase; 53.6 %, cellulase; and 28.6 %, urease. The data obtained expand current knowledge about the diversity of microbial communities in soils of the Selenga Highlands and also confirm the potential of searching for new actinobacteria species in these soils.
Habilidades sociais educativas de pais de crianças com TEA: caracterização e relação com as habilidades sociais dos filhos
Authors: Girotto Agostini Júlia Maria , Cordeiro Freitas Lucas
Published: July 2023

Este estudo teve como objetivo geral caracterizar o repertório de habilidades sociais educativas de pais de crianças com Transtorno do Espectro Autista e relacionar com as habilidades sociais dos seus filhos. Participaram 62 pais/cuidadores, de crianças entre 3 e 12 anos atendidas em Serviços Especializados de Reabilitação de uma microrregião da Zona da Mata/Minas Gerais, Brasil. Foram utilizados o Inventário de Habilidades Sociais Educativas (IHSE-Del Prette) e o Inventário de Habilidades Sociais, Problemas de Comportamento e Competência Acadêmica de Crianças (SSRS). Obteve-se correlação positiva entre escores gerais dos dois instrumentos e a maioria dos fatores. As habilidades de conversar/dialogar dos pais mostraram-se fortes preditoras das habilidades sociais das crianças. Discutem-se as implicações dos resultados para intervenções junto a pais de crianças com autismo.
Ensino de Matemática: fundamentação epistemológica, significado e aprendizagem
Authors: Becker Fernando
Published: July 2023

Apresenta-se parte da pesquisa Epistemologia Subjacente ao Trabalho Docente, com dados coletados no Peru, Chile e Uruguai, mediante entrevistas a 17 docentes, do primeiro ao terceiro grau de ensino. Ela visa a identificar concepções epistemológicas que fundamentam o ensino de Matemática e verificar se tais concepções assemelham-se às encontradas no Brasil. O objetivo desta análise é apreender as concepções epistemológicas subjacentes às respostas às questões 20-23 da pesquisa. Os docentes supervalorizam a matemática que ensinam e pensam que os estudantes a subestimam. O resultado é a quase total ausência da compreensão de que os conhecimentos matemáticos resultam de processos construtivos. Atribuem as aprendizagens ao ensino (empirismo), sem tematizar a origem de tais capacidades ou estruturas (apriorismo); acreditam amplamente em sua realização pela memorização de algoritmos, pondo em segundo plano processos criativos e inventivos como a resolução de problemas. A referência teórica básica é a Epistemologia Genética piagetiana.
Escala de Actitudes hacia el Trabajo en Equipo: diseño y validez de contenido
Authors: Idme Apaza Leyda Flor , Ordoñez Xavier
Published: July 2023

Se diseñó y analizó la validez de contenido de la escala Actitudes hacia el Trabajo en Equipo (AHTE). Los ítems se redactaron desde una aproximación de competencia universitaria y se distribuyen en 4 dimensiones: Identidad, Comunicación, Regulación y Ejecución. Se evaluó pertinencia teórica, pertinencia instrumental, representatividad, dominio, valencia, singularidad y claridad a 104 ítems mediante juicio de expertos (n=23). Se emplearon los Índices de validez de contenido: CVR, CVI, CVC y V de Aiken. Los resultados muestran valores cercanos a 0.80 en CVI y valores mayores de 0.9 en Media de CVC y Media de V de Aiken, siendo la claridad la propiedad a mejorar en 28 ítems. En conclusión, la escala AHTE tiene evidencia de validez de contenido.
Optimization of Genetic Transformation on Phytochrome A by Directly Differentiated Buds in Alfalfa
Authors: Shi Pengfei , Gao Yanping , Lei Ying , Fan Wenna , Yang Yixin , Shi Yaqi
Published: July 2023

Background: The study showed that phytochrome A (phyA) is involved in alfalfa fall dormancy regulation. To provide the scientific basis for using fall dormancy to predict new varieties’ dormancy class from the molecular level, cultivate alfalfa varieties with cold solid resistance and weak fall dormancy and improve the fall dormancy level of existing excellent types, we could study its function through gene silencing. But the genetic transformation rate is not high, which affects the research progress. Methods: To optimize the genetic transformation system in alfalfa (Medicago sativa L.), a binary plasmid vector pART27-phyA was transferred into alfalfa in Agrobacterium tumefaciens-mediated way. To improve transformation efficiency, we optimized the mediums by screening different Kan (Kanamycin) concentrations, NAA (a-Naphthylacetic acid) concentrations and adding YE (yeast extracts). Result: The results showed that using cotyledon nodes as explants, the proper concentration of Kan antibiotics resistance screening was 100 mg/L, the appropriate concentration of NAA for inducing cotyledon node differentiation was 0.1 mg/L and 0.2 g/L YE was suitable to add on the root induction medium; The expression of phyA in terminal buds and leaves of transformed plants of T1 and T2 generations of phyA in Reindeer was significantly reduced (P less than 0.05), but the expression trend in roots and stems had decreasing trend with no significant changes.
Caracterización y análisis de los micronegocios en Colombia
Authors: Cerinza Martin Diana , Montoya Arevalo Nelson Leonardo
Published: July 2023

Se presentan los resultados de una investigación cuyo objetivo general fue caracterizar y analizar los aspectos principales de los micronegocios en Colombia. Se aborda la cobertura en el territorio nacional y se profundiza en las diferencias entre zonas rurales y urbanas, el nivel de empleabilidad, la preferencia para emprender este tipo de proyectos según el género, los rangos de edad y las costumbres de estos emprendedores. También se analizan los diferentes sectores de la economía del país a los que pertenecen estos micronegocios, con lo cual se identifica su distribución por zonas o regiones y la cantidad de micronegocios que fueron beneficiarios de políticas gubernamentales. A partir de esto, se logra brindar un panorama amplio de la realidad actual de los micronegocios en Colombia.
Dampak Penggunaan Media Digital dalam Sikap Apatis Remaja di Kecamatan Sei Rampah
Authors: Nasution Muhammad Azruddin , Harahap Nursapia
Published: July 2023

Penelitian ini bertujuan untuk mengetahui dampak dari media digital terhadap seorang remaja dan seberapa besar tingkat apatis remaja yang dipengaruhi oleh media digital. Metode penelitian yang digunakan adalah kualitatif deskriptif dengan pendekatan fenomenologi. Pengumpulan data dilakukan dengan melakukan wawancara terhadap 5 narasumber. Hasil penelitian menemukan bahwa dampak penggunaan media digital dalam sikap apatis remaja di kecamatan Sei Rampah, yaitu semua dampak penggunaan media digital tersebut tergantung dari pribadi yang menggunakannya, setiap orang khususnya remaja merasakan dampak yang berbeda-beda terhadap tingkat apatis individu dikarenakan penggunaan media digital terkhusus media sosial. Sebagian remaja ada yang merasakan menjadi apatis karena penggunaan media digital yang terlalu sering namun, Sebagian remaja lainnya tidak beranggapan seperti itu.
El decomiso de ganancias como instrumento para la lucha contra la criminalidad organizada, terrorismo, criminalidad económica y ciberdelincuencia
Authors: Nunes Duarte Rodrigues
Published: July 2023

En este artículo se analiza la necesidad y admisibilidad del decomiso de ganancias como instrumento de lucha contra la criminalidad organizada, terrorismo, criminalidad económica y ciberdelincuencia. El punto de partida es el Derecho portugués, sin prejuicio de referencias al Derecho internacional, de la Unión Europea y extranjero siempre que esté justificado. Una vez delimitado el concepto de ganancia y enumeradas las razones de la necesidad de combatir eficazmente el lucro ilícito, se analizan las diversas modalidades de decomiso de ganancias, entre las cuales se encuentran el decomiso “clásico” de bienes de terceros y sin condena, el decomiso ampliado y el decomiso civil in rem, así como en qué medida estas modalidades de decomiso permiten superar las insuficiencias del decomiso “clásico” dependiente de una condena y del establecimiento de un vínculo entre el delito por el cual el acusado es condenado y la obtención de las ganancias para responder eficazmente a las referidas modalidades delictivas. Por fin, son también analizados el objeto y la naturaleza jurídica del decomiso de ganancias y la admisibilidad del decomiso ser acordado bajo el estándar de prueba del proceso civil y de la presunción legal del origen delictivo del valor correspondiente al valor total de la propiedad del imputado cuyo origen lícito no resulta probado en el decomiso ampliado, concluyendo que son admisibles.
Processo penal e o sensacionalismo midiático
Authors: Bandeira Paloma Gurgel de Oliveira Cerqueira
Published: July 2023

Este trabalho tem como objetivo analisar os impactos e a inconstitucionalidade da cobertura midiática sensacionalista sobre os inquéritos policiais e processos penais no sistema judiciário brasileiro, através do método indutivo. A mídia é um meio de veiculação das notícias em nossa sociedade, exercendo importante papel da disseminação de informação e controle social sobre os Órgãos e Poderes públicos. No entanto, principalmente nas últimas décadas, é perceptível o caráter sensacionalista das matérias veiculadas em âmbito penal. Muitas vezes a apresentação midiática de casos penais é feita sem a necessária impessoalidade, atacando sobremaneira a figura de réus e acusados. É perceptível nas matérias jornalísticas com pautas policiais a formação da conclusão de culpa nelas mesmas, sem garantia ao acusado de qualquer tipo de defesa. Há uma espécie de execração pública das pessoas que têm contra si um inquérito policial ou processo penal, tendo em vista meramente os fins lucrativos dos canais de veiculação de notícia. Muito embora seja possível ver a influência midiática primordialmente no público comum, nos últimos anos podemos ver a interferência do sensacionalismo midiático também no âmbito de processos penais, tendo este – em algumas ocasiões – interferido diretamente nos rumos de processos. Foi o que ocorreu, por exemplo, com a famigerada Operação Lava-Jato. Neste estudo, firmou-se a hipótese de que o sensacionalismo midiático fere uma série de prerrogativas e direitos constitucionalmente assegurados aos acusados/réus, o que foi confirmado na conclusão do estudo.
The judicilization of the air sector in Brazil: a diffcult turbulence to overcome
Authors: Lunardelli José Marcos , Fresca Fabio
Published: July 2023

Applied to the theme of repetitive demands, when dealing with efficiency and maximization of wealth, the Economic Analysis of Law indicates the probable existence of an imbalance, which always occurs in a relationship when the benefits obtained at the end of the process are greater than the marginal costs of opting for non-judicialization. Using the Economic Analysis of Law, as theory and method, this article asks: Do facilitated access to justice, low litigation costs and the amount of compensation arbitrated in lawsuits influence consumer behavior in the context of repetitive litigation under the approach of the Economic Analysis of Law? The hypothesis is that facilitated access to justice, low costs of litigation and arbitrated damages in lawsuits influence consumer behavior in the context of repetitive litigation in the airline industry. The study analyzed the conceptual and methodological aspects of the theory of Economic Analysis of Law in the context of the increasing judicialization of the air sector from the air blackout occurred in October 2006. The research was bibliographic, based on secondary data, obtained in books, scientific articles, theses and dissertations, electronic networks, through which were explored the possible correlation between norms and judicial decisions and the phenomenon of increasing litigation in the Brazilian air sector under the theoretical approach of the Economic Analysis of Law. The result of the survey indicates the need to change the existing incentives that contribute to the increasing volume of repetitive demands in the air sector.
Improving Undergraduate Students’ Argumentation Skills Through Problem-Based E-Module with Socio-Scientific Issues Topics
Authors: Wati Anastasya Febrina Enggar , Sari Murni Sapta , Suhadi Suhadi
Published: July 2023

E-module is considered as an effective learning media to create an interactive learning environment. In spite of that it is rare to find the research that examines the development of e-module based on Problem-Based Learning model that integrates Socio-Scientific Issues on argumentation skills to students. This research aims to develop students’ argumentation skills through problem-based e-module with socio-scientific issues topics. The researcher used pre-experimental method with one-group-pretest-posttest design. The e-module was implemented to 36 students of Biology Education, State University of Malang, for the 2nd-year from November to December 2022. The research sample was selected by non-random sampling. The research samples were selected by non-random sampling. The research data were collected by opened-ended questions to assess the students’ argumentation skills and categorized based on the argumentation skills rubric. The data were analyzed based on the increase of pre-test and post-test scores by using Normalized Gain (N-Gain).  The result of the N-Gain calculation showed a score of 0.46 which means the students’ argumentation skills developed in the moderate category after the implementation of using problem-based e-module with socio-scientific issues topics. The problem-based e-module with socio-scientific issues topics can train students to identify the problems, analyze data and evidence to give problem-solving solutions packaged of complex argumentation.
Developing of Electronic Module on Problem-based Learning (PBL) to Improve Creative Thinking Skills
Authors: Raviqah Dianatur , Rohman Fatchur , Lestari Sri Rahayu
Published: July 2023

Creative thinking skills can be empowered to students during the learning process using appropriate learning materials. The study aimed to develop electronic module on problem-based learning that is valid, practical and effective to improve students' creative thinking skills. This development follows the model of Lee & Owens (Assessment/ analysis; Design; Development; Implementation; and Evaluation). The validity was determined based on expert assessment (media, material, educational practitioners) and practicality was evaluated based on field practitioners and students' responses which were analyzed descriptive quantitative percentages. Meanwhile, the effectiveness data were collected through open questions to assess the improve in creative thinking skills based on the rubric of creative thinking skills and analyzed using the N-gain score. The results showed that the developed electronic module on problem-based learning was declared as very valid (98.6%), very practical based on practitioners' responses (93.55%) students' responses (95.92%), and effective for improving creative thinking skills (0,35). Hence, it can be concluded that electronic module on problem-based learning can be used to improve students' creative thinking skills.
Tatrzańskie pisma Bronisława Rajchmana na tle koncepcji „wycieczki bez programu” Tytusa Chałubińskiego
Authors: Grzęda Ewa
Published: July 2023

The article focuses on Bronisław Rajchman’s little known accounts of trips across the Tatra Mountains, which originated in the second half of the 19th century and which are part of strictly defined Tatra tourism literature. Rajchman’s accounts are an important record of the phenomenon of “itinerary-less trips” organised by Tytus Chałubiński. Rajchman was their active witness and participant. In the second half of the 19th century Rajchman’s literary oeuvre, in the form of travelogues, made a significant contribution to the popularisation of Tatra tourism and, at the same time, enriched the Polish writings relating to the Tatra Mountains. In the article the author analyses Rajchman’s two most interesting pieces: “Wycieczka do Morskiego Oka przez przełęcz Mięguszowiecką” [A trip to Morskie Oko through the Mięguszowiecka Pass] (Ateneum, 1877) and “Wycieczka na Łomnicę odbyta pod wodzą dra T. Chałubińskiego” [A trip to Łomnica under the guidance of Dr T. Chałubiński] (1879) in the context of Chałubiński’s activity in Zakopane. The author pays particular attention to the exploratory and guiding aspects of Rajchman’s Tatra prose.
AESTHETIC VALUE: ATTACHMENT TO DIGITAL EXPERIENCE AND REAL-LIFE EXPERIENCE
Authors:   Ph.D. in Design Candidate, Faculty of Decorative Arts, Silpakorn University, Bangkok, Thailand, Sirikhvunchai Natcha
Published: July 2023

The purpose of this academic article was to proof the phrase “Phygital Experiences” by present the merging of digital experiences and real-life experiences in the view of value and aesthetics through 5 roles of digital approach, namely, the role of digital age towards education, the role of digital age towards work, the role of digital age towards economy, the role of digital age towards art and culture, and the role of digital age towards tourism. The study results revealed that technological evolution brings about new forms of interaction that people across the world consume and treat each other. Though digital experience enables people to have comfort, access information and communicate with each other more easily, people do not have profundity and meticulousness to understand experience. On the contrary, real-life experiences offer more experiences of participation in terms of sensory perception or emotional perception. However, they are unable to offer borderless connection and data accessibility as comfortable as digital experiences. Therefore, it can be said that digital experiences and real-life experiences cannot be separated since both of them can fulfill human’s good experiences in a different way, making humans feel fulfilled and enjoyable while they can admire things surrounding themselves. Humans receive benefits from technologies while connecting to the world they can touch.
GLOBAL E-LEARNING AND EXPERIENTIAL OPPORTUNITIES FOR PROGRAMS AND STUDENTS
Authors:   Associate Professor, Troy University, Phenix City, Alabama, United States of America, Paquette Paige , Milligan Meg ,   Professor, Troy University, Phenix City, Alabama, United States of America
Published: July 2023

Electronic learning (e-learning), pedagogy using online technology without physical proximity among the people involved, accelerated due to the recent pandemic and continues its metamorphosis in our endemic world. This new world creates new opportunities to apply e-learning in global contexts, by itself or blended with traditional methods as conditions warrant. Four iterations of a model are described and discussed in terms of adaptability, student satisfaction variables, development of intercultural competence, and global identity. The newest iteration combines previous iterations' e-learning and experiential learning opportunities with participants' occupational and program-specific experiences. The authors include testable outcomes and future possibilities.
LINGUISTIC LANDSCAPE AND CULTURAL GLOBALIZATION: A COMPARATIVE STUDY OF SIGNAGES IN A MULTI CULTURAL ENVIRONMENT
Authors:   Lecturer, Linguistics, Literature and Language Education for Sustainability (LLLES), School of Liberal Arts, Mae Fah Luang University, Chiang Rai, Thailand, Champakaew Wilawan , Suejam Nattapat ,   Fourth Year Student, School of Liberal Arts, Mae Fah Luang University, Chiang Rai, Thailand, Chuaychoowong Maneerat ,   Lecturer, Linguistics, Literature and Language Education for Sustainability (LLLES), School of Liberal Arts, Mae Fah Luang University, Chiang Rai, Thailand
Published: July 2023

This research paper has two main objectives which are 1) to study signages displayed in multicultural environments and 2) to compare and contrast the similarities and differences between two multicultural areas. These two objectives have led to two research questions; (1) What are the languages displayed on signages in the two multicultural areas? And, (2) what are the functions of the signages found in the two multicultural areas? To answer these two questions, the researchers employed two main frameworks: types of signages by Siwina and Prasithrathsint (2020) and functions of signages by Yanhong and RungRuang (2013). The results show that most languages displayed on signages in the Chinese temple are bilingual, monolingual, and multilingual. On the other hand, most of the languages displayed on signages in the Hinduism temple are monolingual, bilingual, and multilingual languages. Moreover, the functions of signages found in the Chinese temple are namely, mythological (18 signages), informational (12 signages), symbolic (6 signages), requesting (2 signages), invitational (2 signages), and instructional (2 signages). Furthermore, from the Hinduism temple, a total of seven functions were found, namely, requesting (11 signages), invitational (12 signages), mythological (4 signages), ordering (3 signages), informational (2 signages), commercial (2 signages), and instructional (1 signage). This study suggested that linguistic landscape plays an important role in creating understanding among multiculturalism in religious settings.
DIAGNOSTIC TEST-BASED ASSESSMENT TOOL USING MOODLE TO MEASURE STUDENTS' METACOGNITIVE ABILITIES
Authors:   Department of Integrated Science, Faculty of Math and Science, Universitas Negeri Semarang, Semarang, Indonesia, Dewi Novi Ratna , Savitri Erna Noor ,   Department of Integrated Science, Faculty of Math and Science, Universitas Negeri Semarang, Semarang, Indonesia, Listiaji Prasety ,   Department of Integrated Science, Faculty of Math and Science, Universitas Negeri Semarang, Semarang, Indonesia, Saputri Luthfi Hanum ,   Department of Integrated Science, Faculty of Math and Science, Universitas Negeri Semarang, Semarang, Indonesia, Dwijayanti Ida ,   Department of Mathematics Educations, Universitas PGRI Semarang, Indonesia
Published: July 2023

As part of mindset, metacognition is one of the key indicators of 21st century skills. In this 21st century learning era, the need for metacognitive assessment tools is very important. This study aims to measure students' metacognitive abilities on science concepts using a Moodle based self-diagnostic assessment and know the correlation between students' metacognitive abilities and their learning outcomes. The research used quantitative methods with a sample consisting of 2 classes of students taking Basic Science Courses Data analysis of students' metacognition level based on evaluation results and correlation analysis of students' metacognition skills and learning outcomes. The result indicated that diagnostic test-based assessment tool using Moodle can be used to measure students' science metacognition abilities. The results also showed a significant correlation between metacognitive abilities and student learning outcomes. Diagnostics test using Moodle can be an alternative metacognitive assessment of the learning process and an opportunity to create a 21st-century skills assessment.
Propositional study of a model for quality evaluation in technical memory deposits in a Digital Library implemented in DSpace
Authors:   Universidade Federal do Rio Grande do Norte, Maia Maria , Coneglian Caio ,   Universidade Estadual Paulista, Shintaku Milton ,   Universidade de Brasília
Published: July 2023

Introduction:One of the forms of dissemination of technical memory occurs through Digital Libraries and Digital Repositories. These information environments can be developed and customized from various software. In Brazil, DSpace is one of the main systems used in the creation of Digital Libraries and Institutional Repositories, thus providing opportunities for the representation, dissemination, access and use of the information made available from these tools. Given such relevance, the information available in these information environments needs to be of quality, in order to ensure numerous contributions to organizations, as well as to their users.Objective:Considering the need to ensure the quality of the information available in Digital Libraries, this study aims to propose a model to foster the improvement of the quality of technical memory deposits in Digital Libraries implemented from the DSpace. Methodology:This is a qualitative and descriptive study, which makes use of the bibliographic survey technique in national and international databases.Results:Based on the bibliographic survey it was possible to propose the model of evaluation of the quality of deposits in Digital Libraries developed from the DSpace, thus presenting contributions to improve the qualityof the information available in these environments so relevant to the dissemination of knowledge. Conclusion:The proposed model will allow interested parties to evaluate the quality of deposits made in Digital Libraries, especially those created through the DSpace software.
Pore filled solid electrolytes with high ionic conduction and electrochemical stability for lithium sulfur battery
Authors: Le Mong Anh , Ahn Yeonho , Puttaswamy Rangaswamy , Kim Dukjoon
Published: July 2023

High lithium (Li)-ion conductive solid electrolytes with mechanical stability are quite important in the development of long-term safe and high-performance solid-state Li-sulfur batteries (LSBs). Accordingly, we prepared a pore-filling solid electrolyte (PFSE) by introducing poly(ethylene glycol) double-grafted (poly(arylene ether sulfone) (PAES-g-2PEG), ionic liquid (IL), and ethylene carbonate (EC) into a porous polypropylene/polyethylene/polypropylene (PP/PE/PP) substrate. While the PP/PE/PP substrate provides the membrane with the mechanical strength, the PAES-g-2PEG filler provides high Li-ion conductivity due to the facile ion conduction pathway formation via percolation in the presence of IL and EC. This synergistic effect allowed the prepared PFSE membranes to exhibit both high mechanical strength of 200 MPa, thermal stability above 150 °C, and high ion conductivity of 0.604 mS cm-1 with a Li-transfer number of 0.41. Moreover, PFSE membranes also achieved a large electrochemical potential window of 4.60 V and high cyclic stability after 500 h of Li-stripping/plating. The LSB cell based on a PFSE membrane showed excellent electrochemical performance with preserving 95% of initial capacity after 200 cycles at a 0.2 C-rate.
Flange connections of chemical technology equipment and pipelines
Authors: Mikulionok Іgor , Karvatskii Anton , Ivanenko Olena , Leleka Serhii
Published: July 2023

The subject of the research is the most common type of detachable joints in chemical, petrochemical, oil refining, food and energy machine and apparatus construction, namely flanged joints of technological and auxiliary equipment, as well as pipelines.

The study of the state of the issue and trends in the development of structural and technological design of flanged joints is based on a critical analysis of scientific and technical sources of information and, above all, patent information of the leading countries of the world, since it is in the patent documentation that information is given about innovative developments in the relevant field of engineering and technology.

With the help of methods of analysis and synthesis, flange connections that affect the efficiency of operation of equipment and pipelines in the chemical and related fields of technology have been systematized. A thorough classification has been developed for each type of device, based on which the most interesting designs proposed by scientists, designers and inventors of the world's leading countries have been examined in detail. A critical assessment of most of the above constructions is provided, their advantages and disadvantages are discussed. Preference is given to sources of information from the end of the second and beginning of the third millennium.

The constructions of flanged joints were analyzed depending on the degree of assembly, the degree of mobility of their structural elements, the possibility of removing the flanges without dismantling the entire joint, the mechanism of compression of the sealing gasket, the presence of additional functions, as well as the material of the flanges.

It is shown that, despite the considerable variety of developed designs of flanged connections, the most demanded by the industry are flat welded and butt-welded flanges, as well as free flanges on a welded ring. However, thanks to the advances in materials science and computer modelling, the search for new flange connection designs continues.

The developed detailed classification of flange connections can be useful to the developers of new equipment for the creation of highly efficient technological equipment of various industries.
EDUCATION IN SECURITY STUDIES: EXPERIENCES WITH THE STUDY PROGRAM OF SECURITY AT THE FACULTY OF SECURITY - SKOPJE
Authors:   Faculty of Security - Skopje, Pelivanova Natasha , Rajkovchevski Rade ,   Faculty of Security - Skopje
Published: July 2023

Education in security studies proves to be crucial for the development of human resources in the institutions of the security system in the Republic of North Macedonia. In response to the requirements for education of staff needed in the security sector, several higher education institutions in the country have accredited study programs in this area. Thus, ten years ago, the first generation of students were enrolled in the study program of security in the first cycle of studies at one of the oldest faculties in the field of security in Southeast Europe - the Faculty of Security - Skopje, at the St. Kliment Ohridski University - Bitola, in order to expand the offer of study programs. The main idea of the paper is to present the historical development of higher education in the area of security in the country through a comparative analysis of the current conditions in certain countries, and to present the results of the limited research conducted on students enrolled in the study program of security at the Faculty of Security - Skopje. The main goal of the paper is to emphasize the importance and significance of education of personnel in the field of security as a necessity in the organization and functioning of the security system, but also to present the experiences and perspectives of authors and students enrolled in the study program. The historical method, the comparative method and the method of analysis will be used in achieving the goals of the paper. Keywords: higher education, security, students, study program.
EDUCATION FOR SECURITY: A GENDER PERSPECTIVE IN THE CURRICULA OF POLICE SCHOOLS IN SERBIA
Authors:   University of Criminal Investigation and Police Studies, Belgrade, Serbia, Spasić Danijela , Radovanović Ivana ,   University of Criminal Investigation and Police Studies, Belgrade, Serbia
Published: July 2023

International documents ratified by Serbia, as well as the progress made at the local level in the last ten years, have led to the issue of gender equality becoming one of the most important for the future development of the country, and such a trend is present in the security sector. Implementing gender equality policy through education is one of the methods necessary in this sector. This is indicated, among other things, by the two action plans adopted so far (in the period from 2010 to 2020) for the implementation of UN Security Council Resolution 1325 "Women, Peace and Security" in Serbia. This paper analyses the degree of implementation of gender equality issues, i.e., gender perspective in educational programs on the example of the curriculum of the University of Criminal Investigation and Police Studies and the professional development program of trainees in the Center for Basic Police Training. Based on the analysis of the content of textbooks and language used in the curricula for education and training of police officers, we came to the conclusion that, despite the fact that certain steps have been taken to introduce a gender perspective in security education programs, this issue remains peripheral and the language used often contains words that emphasize gender stereotypes. In conclusion, it was recommended that the gender perspective is not only an integral part of these programs, but also reflects on the content of educational programs and the language in which they are written, which would promote gender equality in the security sector. Keywords: gender equality, gender perspective, security sector, educational programs
FROM ETHNOPOPULISM TO SECURITY RISKS
Authors:   Faculty of Law Iustinianus Primus, UKIM -Skopje, Chupeska Ana
Published: July 2023

Erin Jenne (2018), in her highly instructive article dedicated to ethnopopulism: Is Nationalism or Ethnopopulism on the Rise Today?, defines ethnopopulism as a “discourse that equates ‘the people’ with ‘the nation’ and holds that sovereignty should be an expression of the will of the ‘nation-people”1 . She refers to Mudde’s notion of the populist radical right2 , denoting the moment when he draws attention to the fact that in recent decades nationalist parties are experiencing their rise and most of these parties are taking on an ethnopopulist form.3 Populism4 , as such, it is worth mentioning, according to Mudde, is an antagonistic ideology, i.e. an ideology that considers that society is divided into two homogeneous and antagonistic groups, "pure people" versus "corrupt elite" and politics should be an expression of the volante general of the people’ / or general will of the people (Mudde, 2004)5 . Later, in line with Stavrakakis and De Cleen, Jenne puts an eye on the notion that populism and nationalism both serve to inscribe the boundaries of the idealized sovereign community more restrictively - excluding elites and “national others”, and also that nationalism is an antagonistic in-out discourse that excludes non-nationals, while populism is an antagonistic up-down discourse that excludes elites or the political establishment (De Cleen 2017; De Cleen and Stavrakakis 2017; De Cleen et al. 2020; Jenne 2022)6 . She elaborates: ….” What happens when nationalism is co-articulated with populism in a single political system?
SECURITY POLICIES IN THE POLITICAL PHILOSOPHY OF PROFESSOR UKSHIN HOTI
Authors:   Ph.D. Candidate Faculty of Security in Skopje, Shala Ibrahim
Published: July 2023

The research for the topic "Security policies in the political philosophy of Professor Ukshin Hoti" is focused on all his published reflections and observations on security issues. His publications are very original, interdisciplinary, and mainly focused on finding the right solution to the Albanian question. The purpose of this paper is to identify and highlight Professor Hoti’s views in the field of security and security policies as expressed though his written works. The main thesis presented here is that Professor Hoti has made significant contributions to the field of security and security policies though his writings in this specific area have not yet been compiled and published in any comprehensive manner. This short study and analysis of the works of Professor Hoti strives to highlight important aspects of his philosophy and thereby make a modest contribution to the field of security literature. Keywords: Ukshin Hoti, security policies, cold war, security, international relations.
AGGRESSIVE BEHAVIOUR AMONG CONVICTS IN THE PRISONS IN MACEDONIA
Authors:   Faculty of Security – Skopje, Batic Dragana
Published: July 2023

This paper is a part of the research conducted in the prisons of the Republic of North Macedonia, under the title "The Position of Convicted Persons in Penitentiary Institutions in Macedonia". The topic refers to the psychological response of convicted persons to their stay in prison, and above all to aggressiveness and its connection with deprivations in prison. The purpose of the research was to determine the degree of aggressiveness and components of aggressiveness, as well as the connection of aggressiveness with deprivations in the prison population. The results showed that recidivists are not more aggressive than first-time convicts, but the aggressiveness of both is higher in relation to norms. Regarding the association of aggression with deprivations from prison, it has been shown that there is an association with deprivations of material goods, heterosexual relationships and freedom as a result of being in prison. In explaining these findings, we used the frustration theory of aggressiveness, according to which all forms of aggressiveness have their source in the frustration of behavior aimed at satisfying some relevant biological need. Based on this research, some recommendations are given for reducing aggressiveness. Key words: aggression, deprivations, prison, convicted persons, frustration