bluuebunny/crossref_metadata_2025 huggingface dataset:
User Engagement Detection-Based Financial Technology Advertising Video Effectiveness Evaluation
Authors: Gao Qun
Published: March 2024

With the rapid advancement of financial technology, an increasing number of related advertisements have received widespread attention. User engagement detection during the advertisement viewing process directly reflects the effectiveness of the advertising video. Therefore, detecting user engagement during the advertisement viewing process has become a crucial issue. However, traditional engagement detection methods often require significant computational resources, significantly reducing their practicality. To address this issue, the authors propose a method to effectively detect user engagement by fully integrating multiple relatively practical models. Specifically, the authors extract key frame images from user face video and perform super-resolution reconstruction of them. Then image pyramid matching is used to achieve user engagement detection. Finally, the authors establish a reasonable database and conduct sufficient experiments based on it. Experimental results demonstrate that this proposed method has realistic engagement detection accuracy, and the design of multiple steps is also valid.
Making Drug Therapy Safer and More Effective Is a Primary Concern for Pharmacists Everywhere
Authors: Alderman Chris
Published: March 2024

Evidence is a critical consideration in any clinical process, where there is usually potential for interventions to cause harm or to have unintended consequences arising from a change to the course of patient management. Pharmacists working in the care of older people are well-versed in this concept, given that medication use can create clinical benefit and drug-related harm through mechanisms such as toxicities and drug interactions. Published in this edition of the journal, there is discussion of the utility of pharmacogenomics to guide drug therapy. This is meritorious science, but if everyone is honest, it is hardly something new, or for that matter, widely used. But what underlies the imperative to continue to disseminate this information in a peer-reviewed, indexed journal? The answer lies not so much in validating the science but in promoting the approach.
Existence and ergodicity for the two-dimensional stochastic Allen–Cahn–Navier–Stokes equations
Authors: Ndongmo Ngana Aristide , Tachim Medjo Theodore
Published: March 2024

We study in this article a stochastic version of a coupled Allen–Cahn–Navier–Stokes model in a two-dimensional bounded domain. The model consists of the Navier–Stokes equations for the velocity, coupled with an Allen–Cahn model for the order (phase) parameter, both endowed with suitable boundary conditions. We prove the existence of solutions via a semigroup approach. We also obtain the existence and uniqueness of an invariant measure via coupling methods.
Dual and triple modulator therapy for chronic rhinosinusitis in cystic fibrosis patients
Authors: Uyttebroek S , Claeyssens C , Jorissen M , Dupont L , Van Gerven L
Published: March 2024

Background: The introduction of CFTR modulators has changed the landscape in the treatment of cystic fibrosis (CF) and early case series have shown improvements in sinonasal outcomes in this patient population. Methodology: A real-word data study was performed to evaluate the impact of dual therapy with tezacaftor/ivacaftor (TEZ/IVA) and triple therapy with elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on CF-related chronic rhinosinusitis (CRS), by comparing subjective and objective outcome measures at baseline, 12 months after treatment with TEZ/IVA and six months after treatment with ELX/TEZ/IVA. Results: In total, 43 CF patients, with a mean age of 32 years, were included. After triple therapy, significant improvements in overall visual analogue scale, SNOT-22, Lund Kennedy, nasal polyps, and Lund-Mackay scores were observed, whereas no beneficial effect could be seen in patients treated with dual therapy. Bacterial upper airway colonization did not differ pre- and postmodulator therapy in the present study. The number of responders to dual and triple therapy is 23.8% and 63.2% of the patients, respectively. Conclusions: Triple therapy with ELX/TEZ/IVA is superior to dual therapy with TEZ/IVA in the treatment of CF-CRS, as significantly reduced sinonasal complaints, nasal endoscopy and CT scores were observed after triple therapy, whereas this was not the case for dual therapy.
Efficacy and Feasibility of Short-Stretch Compression Therapy for Filarial Lymphedema in Sri Lanka
Authors: Hall Jaimee M. , De Silva Nirmitha Lalindi , Ruben Janaka , Thilakarathne Sandani S. , Yahathugoda Thishan Channa , Budge Philip J.
Published: March 2024

The WHO-recommended essential package of care (EPC) for filarial limb lymphedema consists of daily limb washing, entry lesion management, limb protection, exercises, and elevation. Decongestive therapy (DT) with compression bandaging by trained lymphedema therapists adds additional benefit but is unavailable for most in low- and middle-income countries (LMICs). To determine whether DT using self-adjustable, short-stretch compression garments (SSCG), prefitted using portable, three-dimensional infrared imaging (3DII), would be effective and feasible in LMIC settings, we conducted a pilot 6-week, interventional, single-group, open-label pilot study in Galle, Sri Lanka. Ten participants with Dreyer stage 3 lymphedema used SSCG for 2 weeks after a 4-week lead-in EPC period. Effect of EPC and compression on quality of life was assessed using the 12-item WHO Disability Assessment Schedule 2.0 (WHODAS 2.0). Median participant age was 73 years (range: 32–85 years). Median percent limb volume reduction due to compression was 11.3% (range: 1.1–27.2%). WHODAS 2.0 scores did not change significantly between enrollment and study end. Garment acceptability was high throughout the study. These results provide proof of concept for 3DII-enabled SSCG in LMICs where trained therapists for filarial lymphedema may not be available.
SARS-CoV-2 Seroprevalence and Vaccine Uptake among Pregnant Women at First Antenatal Care Visits in Malawi
Authors: Tenthani Lyson , Seffren Victoria , Kabaghe Alinune Nathanael , Ogollah Francis , Soko Monica , Yadav Ruchi , Kayigamba Felix , Payne Danielle , Wadonda-Kabondo Nellie , Kampira Elizabeth , Volkmann Tyson , Sugandhi Nandita S. , Seydel Karl , Rogier Eric , Thwing Julie I. , Gutman Julie R.
Published: March 2024

Many SARS-CoV-2 infections are asymptomatic, thus reported cases underestimate actual cases. To improve estimates, we conducted surveillance for SARS-CoV-2 seroprevalence among pregnant women attending their first antenatal care visit (ANC1) from June 2021 through May 2022. We administered a questionnaire to collect demographic, risk factors, and COVID-19 vaccine status information and tested dried blood spots for SARS-CoV-2 antibodies. Although <1% of ANC1 participants reported having had COVID-19, monthly SARS-CoV-2 seroprevalence increased from 15.4% (95% CI: 10.5–21.5) in June 2021 to 65.5% (95% CI: 55.5–73.7) in May 2022. Although COVID-19 vaccination was available in March 2021, uptake remained low, reaching a maximum of 9.5% (95% CI: 5.7–14.8) in May 2022. Results of ANC1 serosurveillance provided prevalence estimates helpful in understanding this population case burden that was available through self-report and national case reports. To improve vaccine uptake, efforts to address fears and misconceptions regarding COVID-19 vaccines are needed.
Case Report: Itraconazole Oral Solution Continuous Therapy for Infantile Tinea Capitis
Authors: Zhou Ya Bin , Chao Jin Jing , Ma Lin , Xiao Yuan Yuan
Published: March 2024

Tinea capitis is a common fungal infection caused by dermatophytes in children, but it is rare in infants. Although oral itraconazole has been widely used to treat tinea capitis, its use in infants is limited due to its low prevalence in this age group. A previous study reported the effectiveness of itraconazole continuous therapy in treating infantile tinea capitis caused by Microsporum canis. However, this approach has not been extended to tinea capitis caused by other fungi. In this study, we present four cases of infantile tinea capitis treated with continuous itraconazole oral solution therapy (5 mg/kg/day). Two patients were infected with M. canis, one patient with Nannizzia gypsea, and another with Trichophyton tonsurans. This study assesses the efficacy and safety of itraconazole oral solution continuous therapy, expanding our understanding by demonstrating its effectiveness for infantile tinea capitis caused by T. tonsurans and N. gypsea.
Chronic pancreatitis: Pain and computed tomography/magnetic resonance imaging findings
Authors: Feng Yue , Song Ling-Ji , Xiao Bo
Published: March 2024

Chronic pancreatitis (CP) is a fibroinflammatory disease characterized by irreversible destruction of pancreatic tissue. With the development of the disease, it may lead to exocrine and/or endocrine insufficiency. CP is one of the common diseases that cause abdominal pain, which will not get permanent spontaneous relief as the disease evolves. The American College of Gastroenterology clinical guidelines recommend computed tomography or magnetic resonance imaging as the first-line examination for the diagnosis of CP. CP common imaging findings include pancreatic atrophy, irregular dilatation of the pancreatic duct, calcification of pancreatic parenchyma, pancreatic duct stones, etc. In clinical practice, whether any correlations between CP-induced abdominal pain patterns (no pain/constant/intermittent pain) and corresponding imaging findings present are not well known. Therefore, this review aims to comprehensively sort out and analyze the relevant information by collecting lots of literature on this field, so as to construct a cross-bridge between the clinical manifestations and imaging manifestations of CP patients. Also, it provides an imaging basis and foundation for the classification and diagnosis of abdominal pain types in clinical CP patients.
The Reasons Behind Changing Foreign-Sounding Surnames in Sweden and Their Development Between 1925 and 2015
Authors: Hedberg Johan
Published: March 2024

In this paper I investigate surname change in Sweden, focusing on the act of changing a foreign-sounding surname and the reasons for surname changes given in applications between the years 1925 and 2015. The various reasons are gathered into different types, and their development over time is investigated further. The results show that the most common type of reason is that the applicant’s current surname causes problems with pronunciation and/or spelling. There is a clear decline in this type of reason between the 1980s and 2010s, which suggests that it has become less problematic to bear a foreign-sounding surname in Sweden in recent decades. This suggestion is further explored with an investigation of how common it has been to change from a foreign-sounding surname to one based on the Swedish language. This investigation shows that it has become less common to change to a surname based on the Swedish language in recent decades.
Языковая идентичность личного имени в контексте языковой ситуации в Украине
Authors: Михальчук Оксана
Published: March 2024

В статье рассматриваются социоономастические аспекты языковой идентичности личного имени. Объектом исследования являются фиксации личного имени в официальных документах. Исходя из категориальной характеристики антропонима как этноязыкового маркера проанализировано влияние лингвополитических, орфографических и правовых факторов на функционирование системы личных имен в Украине. В частности автор ищет ответы на вопросы: а) каким образом записи имен в официальных личных документах отображают языковую ситуацию и состояния языкового сознания?; б) какие факты изменений в структуре национальной системы имен являются последствием языковых политик и какие отображают результаты языковых контактов?; в) как это влияет на эколингвистический баланс и стабильность национального фонда личных имен? Важное место принадлежит описанию влияния языковой самоидентификации индивидов на выбор личного имени при регистрации новорожденных. Особое внимание уделено проблемам документальной фиксации имен представителей национальных меньшинств и групп, а также особенностям адаптации в украинской системе личных имен новых заимствований. Отмечено, что право на имя и языковая идентичность имени в условиях глобализации обретают новые черты, связанные с функционированием и коммуникативным комфортом в разных языковых кодах. Изучение идентичности личных имен позволяет сформулировать основные социолингвистические критерии правовых и языковых норм для измерения качества современного национального корпуса личных имен. Изучение языковой идентичности имени связано также с перспективой разработки расширенных инструкций по правописанию имен.
The COVID-19 Pandemic Through the Environmental Discourse: the State, Civil Society, the Problems of Development
Authors: Burkova E. I.
Published: March 2024

This paper examines the response of political communities to the COVID-19 pandemic. Using methodological approaches such as political globalism, world-system and structural-functional analysis, the author examines the political conditions of nation-states for coping with the pandemic and its consequences. Within this framework, the problem of the systemic crisis of the modern state, the effectiveness of public administration and decision-making systems was also addressed. The focus was on issues of political development, considered in the context of the evolution of democracy, civic political participation, the role of non-governmental organisations and elites, and the relationship between values and goals in the global and national political agenda. The article also touches upon the problem of “infodemics.” The paper concludes with recommendations for adding an environmental component to the concept of national security.
Environmental Agenda in the Modern Chinese Sea Policy
Authors: Navdaeva M. E.
Published: March 2024

The article is devoted to the study of the role of marine ecology protection in the modern political course of China. Today, the ocean has great importance in Chinese development from an economic, energy, and resource point of view. However, its benefits are threatened by the environmental problems caused by anthropogenic pressure due to the development of human society, population growth, and industry. Currently, China faces plastic, waste, and oil pollution, illegal activities leading to the depletion of food resources, increasing ocean acidification due to air pollution, and degradation of the coastal environment. Awareness of the importance of the ocean for domestic and foreign policy forces China to take measures to protect it. At the same time, since the environmental agenda in modern international relations acts both as an instrument of pressure and as a means of political rise, it is effectively used by China in the struggle for global leadership both in the environmental protection sphere and in the world in general. Using the environmental agenda as a peaceful means of rising, China seeks to transform the current global order while showing itself as a responsible world leader.
Energy Diplomacy in the Era of Energy Transition
Authors: Aliev R. A.
Published: March 2024

The development of international relations after the 1973 oil crisis was accompanied by the emergence of such phenomena and concepts as global and regional energy security, energy security of states, foreign energy policy and energy diplomacy. Institutionalization and development of mechanisms ensuring energy security – including global energy security – occurred and continues to occur under the conditions of dominance of hydrocarbon fossil fuels in the world energy balance, as well as in the context of energy consumption worldwide. The priorities of its provision at the global, regional and state levels were and are the security of demand, supply and transit of hydrocarbon raw materials, and the diversification of energy sources. After signing the Paris Climate Agreement in 2015, efforts are being made to accelerate the low-carbon transformation of the world economy and the pace of the global energy transition. This involves mechanisms for responsible investment, carbon regulation, greenhouse gas emissions management (climate management); uses a variety of socially significant interpretations of ongoing climate change. These processes are increasingly determining the foreign energy policy of states, international energy diplomacy and influencing the previously formed mechanisms for ensuring energy security. The article is aimed at generalization and systematization of the ongoing changes in the activities of both traditional international centers and institutes of global energy policy, and relatively new international platforms in the subject area under consideration, primarily the Conferences of the Parties to the United Nations Framework Convention on Climate Change and their impact on energy policy and energy diplomacy.
NRF2'nin İkili Doğası: Kanser Gelişiminde Koruyucu ve Teşvik Edici Rolü
Authors: Kaleler İslim , Yaylım İlhan
Published: March 2024

Nükleer Faktör Eritroid 2 ile İlişkili Faktör 2 (NRF2), hücrede başlıca oksidatif hasara karşı koruyucu olmakla birlikte metabolizmanın düzenlenmesinde de rolü olan transkripsiyon faktörüdür ve hücresel redoks dengesinin sağlanmasında merkezi rol oynar. Kanserin tedavisi için anahtar mekanizmalardan birisi NRF2 yolağıdır. NRF2-KEAP1 yolağının koruyucu rolleri göz önüne alındığında, aktivasyonunun bir dizi antioksidan mekanizmayı destekleyerek kanser oluşumunu etkili bir şekilde önleyebileceğini düşündürmektedir. Bu nedenle NRF2’nin kanser gelişimindeki ve ilerlemesindeki rolleri yoğun bir şekilde araştırılmaktadır. Başlangıçta kansere karşı koruyucu olduğu ortaya konmasına rağmen, günümüzde kanseri desteklediği de bulunmuştur. Kanserde umut verici terapötik bir hedef olarak görülmekte ve oynadığı “iki yönlü” rolden dolayı NRF2’nin hem aktivatörleri hem de inhibitörleri giderek artan ilgi çekici bir araştırma alanı olmaktadır.
Determining the Fear of COVID-19 in Parents and Affecting Factors
Authors: Kadiroğlu Türkan , Kurudirek Fatma , Akay Gamze
Published: March 2024

Aim: This research was conducted to determine the fear of COVID-19 in parents during the pandemic and the factors affecting it.
Material and Method: This research is both a descriptive and cross-sectional study. The research was conducted with parents (both health personnel and not) inhabiting Erzurum. The sample group was determined by the smallest sampling method calculation formula and 511 parents were reached. "Introductory Information Form" and "COVID-19 Fear Scale," were used as data collection tools in the study.
Results: COVID-19 fear level of parents who had low income and sent their children to kindergartens/daycares was substantially high. The levels of COVID-19 fear in parents are on average.
Conclusion: According to the findings of the research, it was determined that the parents' COVID-19 fear levels are average. The COVID-19 fear level of parents who had low income and sent their children to kindergartens/daycares was substantially high. Besides, COVID-19-related fear affected the habit of going out and the life qualities of parents. The increased COVID-19 fear level has its negative share considering children, parents, and social background; therefore, every activity that can help social and mental health should be supported.
Festa, parentesco e sinestesia xucuru-kariri
Authors: Bort Jr. João Roberto
Published: March 2024

Aromas, sabores, imagens, cores, sons e movimentos compõem as relações que os Xucuru-Kariri estabelecem com entes encantados em suas periódicas festas na mata do Alto Rio Pardo (município de Caldas, Minas Gerais). A ideia de descrever essa cosmopolítica sinestésica é conhecer seres e forças da natureza às quais a pessoa guerreira dos indígenas existe ontologicamente relacionada. Para tanto, o artigo se dedica a alguns dos termos e práticas xucuru-kariri no cuidado com o corpo e ao papel de seus parentes – em especial dos avós rituais – no preparo de coisas e comidas em mais de um lugar da área de habitação cotidiana da aldeia.
Notas sobre luta, Encantados e o povo Pataxó Hãhãhãi
Authors: De Andrade Souza Jurema Machado
Published: March 2024

Este artigo apresenta situações e relatos das relações entre o Povo Pataxó Hãhãhãi na Terra Indígena Caramuru-Paraguassu, localizada entre os municípios de Pau Brasil, Itaju do Colônia e Camacã, no sul da Bahia, e seus múltiplos seres outros-que-humanos, fundamentais para o convívio cotidiano e a luta. Assim, a partir de pesquisa etnográfica realizada em distintos momentos históricos, durante duas décadas, são descritos eventos que envolvem a relação desse povo com a jurema, o cachimbo e o tabaco, com a terra, as pessoas e os Encantados. Finalmente, destaca-se, sobretudo, o papel do ritual e da ação dos Encantados nas ações de retomadas de terras efetuadas durante trinta anos de ocupação integral do território tradicional.
Clóvis Moura e a Sociologia do Negro: uma teoria/práxis marxista e radical
Authors: De Oliveira Fábio Nogueira
Published: March 2024

MOURA, Clóvis. A Sociologia do Negro Brasileiro. São Paulo, Ed. Perspectiva, 2020.
New Paradigms of Sustainability in the Contemporary Era
Authors: Pareek Ritu
Published: March 2024

As our world grapples with the profound challenges of the 21st century, the concept of sustainability has emerged as a guiding light, illuminating the path towards a more equitable, resilient, and harmonious future. This edited volume, “New Paradigms of Sustainability in the Contemporary Era,” presents a collection of diverse voices and groundbreaking perspectives that collectively redefine how we perceive and approach sustainability in our rapidly evolving world. In this volume, we explore the multifaceted dimensions of sustainability, encompassing not only environmental stewardship but also social inclusivity, economic resilience, and cultural preservation. We delve into innovative paradigms that acknowledge the intricate interplay of these elements, offering fresh perspectives and trans-formative solutions. One of the central themes in this volume is the redefinition of sustainability as a holistic concept. Contributors to this volume challenge conventional silos, encouraging us to view sustainability through a more comprehensive and integrative lens. As we navigate the challenges and opportunities of the contemporary era, let this edited volume serve as a source of inspiration and a catalyst for action. Together, we can embrace new paradigms of sustainability, redefining our relationship with the planet, each other, and the future generations who will inherit the world we shape today.
Fostering Sustainable Development in Water Supply Management: Crucial Role of Credible HR Capacity Building
Authors: Kumawat Dharmendra , Sharma Roopali
Published: March 2024

Drinking water is the essence of life, so the concerns about its management touch millions of lives every day. Jal Jeevan Mission ambitiously targets for providing safe drinking water to each rural household in India on a mission mode. This project envisages pooling of resources (including human resources) Just in Time with lean overheads. Capacity building is not an option; it is, practically, ‘essential’ given the enormity of challenges during implementation and post-implementation phases of this project. Outsourcing cuts down government investments on grooming and fostering of staff. However, diminishing trade unionism, unorganized neo-trained workforce and feeble government control may affect the quality of employment fetched through the outsourcing agencies. This paper specifically examines the human resource capacities under Jal Jeevan Mission-Rajasthan, aiming to impart more sustainability in drinking water supply services. It documents issues related to transition in the institutional role, existing shortfalls in the capacities and suggests potential areas for strengthening. The study will empower young minds to work in a new framework, help policymakers to frame lasting policies and guide the outsourcing agencies to stretch beyond switching job-cards.
Enhancing Data Security in Cloud Computing Using Blockchain
Authors: Dagar Ritu , Mahajan Dr. Shilpa , Vashisht Dr. Rohit
Published: March 2024

As cloud computing continues to proliferate, ensuring data security within cloud environments becomes increasingly critical. This paper explores the integration of blockchain technology as a means to enhance data security in cloud computing. Blockchain, with its decentralized and immutable ledger system, offers unique capabilities that address key security challenges such as data privacy, integrity, identity management, and compliance. Through a comprehensive analysis of blockchain's potential applications and integration strategies, this paper provides insights into how blockchain can bolster data security in cloud computing environments. Case studies and real-world implementations highlight successful integration efforts by major cloud service providers such as IBM, Microsoft, and Amazon. Additionally, this paper discusses the challenges and limitations associated with blockchain integration and explores future directions and emerging trends in the intersection of blockchain and cloud security. By leveraging blockchain technology, organizations can enhance their security posture in the cloud, ensuring the confidentiality, integrity, and availability of their sensitive data.
Tradisi Peletakan Poster Ayat Al-Quran Pada Rumah Makan Di Sampit Provinsi Kalimantan Tengah
Authors: Lukman Hakim  , Ahmad Fauziannur
Published: March 2024

Tulisan ini berawal dari sebuah fenomena menarik yang penulis temukan yakni hampir seluruh rumah makan yang berada sampit khusunya di rest area sekitaran jalan trans Kalimantan yang menghubungkan kabupaten Kotawaringin Timur dan Kota Palangaka Raya memiliki tradisi unik yakni meletakan ayat al-Qur’an di dinding rumah makan tersebut yang dalam hal ini merupakan bagian dari study living Qur’an. Dari hasil temuan penelitian diketahui bahwa living Qur’an yang dilakukan dengan meletaknan ayat al-Qur’an oleh para pemilik rumah makan tersebut merupakan sebuah bentuk komunikasi trasendental kepada Allah SWT. Di mana dengan meletakan ayat al- Qur’an tersebut pemilik rumah makan berharap Allah SWT dapat mencurahkan rahmatnya dan lindungan-Nya pada keluarga dan tempat usaha yang dimiliki. Living Qur’an yang dilakukan juga sebagai penegasan identitas diri dari para pemilik rumah makan tersebut sebagai seorang muslim, dengan tujuan agar para pengunjung mengetahuinya dan dapat membantu para pengunjung untuk mendapatkan makanan yang halal dan baik dimakan.
Genetic Diversity of Cucumber Mosaic Virus in Cucumber Plants Grown in Diyarbakır Province
Authors: Güller Abdullah , Demirel Serap , Usta Mustafa , Korkmaz Gülüstan
Published: March 2024

The cucumber plant (Cucumis sativus L) is an important cultivated plant produced worldwide. Cucumber mosaic virus (Cucumber mosaic virus, CMV), one of the common viral diseases, causes economic losses by reducing the yield and quality of the cucumber plant. In the observations performed in Diyarbakır in September 2021, cucumber plants showing virus-like symptoms such as mosaic, irregular yellowish spots, and deformity on the leaves were observed. Symptomatic and non-symptomatic samples were collected and subjected to a polymerase chain reaction (PCR) using CMV-specific primers, and the produced DNA bands were visualized on an agarose gel. CMV infection was detected in seven of the 15 samples. Bacterial cloning and sequencing of a randomly selected specimen determined that the CMV partial coat protein gene was 593 bp long and was registered in the NCBI database with the accession number MW962979.1. According to the phylogenetic tree performed with different isolates of CMV, Diyarbakir CMV isolate clustered with CMV isolates from Australia, Israel, Spain, Hungary, Japan, and Korea forming Subgroup IA. The presence of CMV and group/subgroup diagnosis in cucumber plants grown in the Diyarbakır region were confirmed molecularly for the first time by this study.
Celtis australis Exhibits Cytotoxic Effects by Inducing DNA Damage in Human Ovarian Cancer Cells
Authors: Fidan Gülsüm Nur , Günay Sevilay , Erden Yavuz
Published: March 2024

Native to the Mediterranean and southwest Asia, Celtis australis is used in folk medicine to treatment of many diseases such as peptic ulcer, diarrhea, dysentery, pain, and colic. However, there are very few studies on the effects of this species on cancer. We report for the first time the cytotoxic and genotoxic properties of C. australis on the human ovarian cancer cell line A2780.

In the study, C. australis extract prepared in ethanol/phosphate buffer was applied to A2780 cells. The change in viability level in A2780 cells after treatment was determined by MTT assay and DNA damage was determined by single-cell gel electrophoresis (Comet) analysis.

Our results showed that plant extract application at doses above 200 µg/ml significantly decreased A2780 cell viability (p
Experimental Study to Determine the Backscattering, Asymmetry, and Tailing Factors for Some Elements in the Atomic Number Range of 4≤Z≤48 at 59.54 keV Using the Gamma Backscattering Method
Authors: Uzunoğlu Zeynep
Published: March 2024

This experimental study has been carried out by using gamma backscattering method which is a non-destructive method. Some elements which are in the atomic number range of 4≤Z≤48 have been used as backscatterer samples to investigate the variation of backscattering factor, asymmetry factor, and tailing factor with atomic number. These samples were irradiated by γ-rays of 59.54 keV energy emitted from a 10 μCi 241Am point radioactive source. To count the backscattered photons from samples, a high purity germanium detector (HPGe) with a resolution of 182 eV at 5.9 keV and active area of 200 mm2 was used. It was concluded that the count rate and backscattering factor increased with increasing atomic number, but the coherent to backscattering ratio, asymmetry factor, and tailing factor decreased.
An Investigation on the Use of Clustering Algorithms for Data Preprocessing in Breast Cancer Diagnosis
Authors: Şenol Ali , Kaya Mahmut
Published: March 2024

Classification algorithms are commonly used as a decision support system for diagnosing many diseases, such as breast cancer. The accuracy of classification algorithms can be affected negatively if the data contains outliers and/or noisy data. For this reason, outlier detection methods are frequently used in this field. In this study, we propose and compare various models that use clustering algorithms to detect outliers in the data preprocessing stage of classification to investigate their effects on classification accuracy. Clustering algorithms such as DBSCAN, HDBSCAN, OPTICS, FuzzyCMeans, and MCMSTClustering (MCMST) were used separately in the data preprocessing stage of the k Nearest Neighbor (kNN) classification algorithm for outlier elimination, and then the results were compared. According to the obtained results, MCMST algorithm was more successful in outlier elimination. The classification accuracy of the kNN + MCMST model was 0.9834, which was the best one, while the accuracy of kNN algorithm without using any data preprocessing was 0.9719.
Convmixer ve SDD Kullanılarak DEHB Hastalığının EEG Sinyalleri ile Otomatik Olarak Tespit Edilmesi
Authors: Karakaş Buğra , Özçelik Salih Taha Alperen , Uyanık Hakan , Üzen Hüseyin , Şengür Abdülkadir
Published: March 2024

DEHB, çocuklarda dikkat eksikliği, davranış problemleri, eğitimle ilgili sorunlar ve düşük özgüven gibi problemler oluşturabilir. Bu çalışma, Dikkat Eksikliği Hiperaktivite Bozukluğu (DEHB) teşhisini elektroensefalografi (EEG) sinyalleriyle değerlendirmeyi hedefleyen bir araştırmayı özetlemektedir. Araştırma, 30 DEHB tanısı almış çocuk ve 30 sağlıklı kontrol grubunun EEG verilerini kullanmıştır. EEG verileri öncelikle gürültü azaltma amacıyla işlenmiş ve ardından ConvMixer, ResNet50 ve ResNet18 gibi derin öğrenme modelleri kullanılarak sınıflandırılmıştır. Bulgular, ConvMixer'in düşük hesaplama kaynaklarına ihtiyaç duyarak yüksek sınıflandırma başarısı elde ettiğini göstermektedir. Ayrıca, EEG sinyallerinin DEHB teşhisinde kullanılabilirliği konusunda farklı kanalların etkileri incelenmiş ve T8 kanalının özellikle etkili olduğu tespit edilmiştir. Bu çalışma, EEG tabanlı DEHB teşhisi için daha hafif modellerin kullanılabilirliğini ve EEG kanallarının önemini vurgulamaktadır.
Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer
Authors: Şahin Yılmaz
Published: March 2024

Prostate cancer is one of the most common types of cancer in men. It usually grows slowly and may not show obvious symptoms at first. Prostate cancer can be diagnosed by symptoms or by a doctor performing certain tests during routine health checkups. These tests include physical examination, PSA (Prostate Specific Antigen) Test, biopsy, imaging techniques, and Gleason score. In addition, Fourier transform infrared spectroscopy (FT-IR) is an analysis method used for prostate cancer diagnosis. This study aims to demonstrate FT-IR spectroscopy as an alternative method to other diagnostic methods in the diagnosis of prostate cancer. The FT-IR spectroscopy method is used to examine the molecular structure of samples. For prostate cancer diagnosis, FT-IR spectroscopy can be used to identify molecular changes in prostate tissue and identify characteristics by which cancerous cells differ from healthy cells. FT-IR spectroscopy is based on spectral data obtained by exposing samples to infrared radiation. These spectral data are based on properties associated with the movements of the molecules contained in the samples, such as vibration, rotation and bending. Molecular changes caused by diseases such as prostate cancer may be evident in these spectral data. These changes can provide information about the presence or stage of cancerous cells. Data obtained using FT-IR spectroscopy is processed with statistical analysis methods. These analyses are used to identify molecular differences between cancerous and healthy prostate tissues. In this way, FTIR spectroscopy can help obtain sensitive and accurate results in the diagnosis of prostate cancer.
Isolation Identification and Molecular Characterization of Lactic Acid Bacteria From Raw Milk Samples Collected from Erzurum Region
Authors: Doğan Selcan , Çanakçı Adıgüzel Gülşah
Published: March 2024

Due to its high-water content, milk is an important source of different microbial contents, especially lactic acid bacteria. The aim of this study is to isolate and identify lactic acid bacteria from raw milk samples collected from Erzurum and its surroundings, and to introduce possible new species, or genera, to the taxonomy. For this purpose, DNAs of pure bacterial cultures obtained from 50 raw milk samples collected from producers in Erzurum and its districts were isolated, isolates that differed from each other were selected by rep-PCR, and 11 different species and subspecies [Corynebacterium casei, Enterococcus italicus, E. durans, Lactococcus lactis, Lactococcos lactis subsp. lactis, Lactococcos lactis subsp. hordniae, Lactobacillus paracasei, Leuconostoc lactis, Staphylococcus succinis, Streptococcus parauberis ve S. uberis] in raw milk samples by 16S rRNA sequence analysis. It was concluded that the (GTG)5-PCR method was more successful than BOX-PCR in the identification of lactic acid bacteria isolated from raw milk samples at a species and subspecies level, and the isolate coded TS10, which was 98% similar Streptococcus uberis, may be a new species and should be re-examined with advanced diagnostic techniques.
Archives Repositioning: Unveiled the Fact, Archives is Information
Authors: Wulandari Sari Agustin
Published: March 2024

This work starts with a very simple question, where do archives position in DIKW pyramid? To know the answer, researcher using an SLR method, with kitchenhamm approach. Other thing, researcher reffer to Data, Information, Knowledge, Wisdom hierarchy or known as piramid of knowledge, the purpose of doing so is to avoid terminology bias.

From that method, researcher found 16 literatures as reference for extraction and sintetycally analized. Boolean string use also being done for simplifying literature filtering from 5 availiable digital database, which is science direct, ACM, Digutal Library, Jstor, Springer and Portal Garuda. The result of this research is only 1 from 16 literatures which consider archives as data, while 15 other literatues consider archives as information in formation knowledge pyramid and decisions making process.
Archives are information: definition, principles, and relation
Authors: Pratama Raistiwar
Published: March 2024

The differences often take place between archives or records and information. As we easily assume, information is more attractive than archives. It is hard to imagine without archives what turns out to be information. That is why we need to have complete paradigm regarding archives since its creation until they are being publicly accessed. In short, archives are information but not all information is considered archives. The two main archival principles (provenance and original order) are crucial for information retrieval. In essence, archives are shaped by their content and medium. In the long run, archival systems or records system is about providing continuing access towards its information and maintaining the medium readability through time.
Testing Ink Resistance on Ballpoint and Stamp Based on Regulation of The National Archives of The Republic of Indonesia No. 7 Year 2018
Authors: Sofiati Dita Ayu , Payanti Tyas Dwi , Rahayu Hesti
Published: March 2024

The use of ballpoint ink and stamp ink is particularly important in the future condition of archives. The ink on the paper is degradable due to natural aging during conservation. It cannot be stopped but must be maintained. This paper aims to examine the durability of ink on ballpoint pens and stamps based on the Republic of Indonesia's National Archives Regulations. Ink samples were soaked in deionized water and soap solution (1% v/v) for 1 hour to identify faded ink on the surface of the paper. Chemical composition of ballpoint ink and stamp ink were analysed using Gas Chromatography Mass Spectrometry (GC-MS) and physical characterization using Video Spectral Comparator (VSC). The results of this study are the ballpoint pens commonly used in ANRI for handwriting and signatures that fade easily. Ballpoint pen inks that do not fade are Standard Lexion LX-105 and Pilot Super GP while ink that does not fade is the Archives Section stamp. The results of the GCMS analysis found 15 chemical compounds with the main compounds being long fatty acid esters. The result of VSC analysis is that each ink has distinct colour characteristics when exposed to Infrared at 645nm.
KEWENANGAN PENYIDIKAN PADA TINDAK PIDANA KORUPSI DALAM SISTEM PERADILAN PIDANA
Authors: Muhammad Romadhan  , Muhammad Nugraha  , Aldy Sopandy  , Zain Agiel Abdullah  , Andreas Jona Situmorang  , Kesuma Derry Angling
Published: March 2024

AbstrakPada hakekatnya hukum diciptakan di dalam pergaulan hidup bermasyarakat, baik dalam lingkungan kecil maupun dalam lingkungan yang lebih besar, agar di dalamnya terdapat keserasian, ketertiban, kepastian hukum dan lain sebagainya. Agar semua orang dapat bertingkah laku yang benar, harus ada ketentuan yang dapat dijadikan tolok ukur. Apabila terjadi perbuatan yang melanggar hukum atau menyimpang dari keserasian, ketertiban dan kedamaian dalam pergaulan hidup maka akan ada hukuman atau pidana berupa sanksi hukum bagi pelakunya. Sanksi hukum ini akan menimbulkan penderitaan baik secara fisik maupun secara mental bagi semua orang yang melakukan kejahatan, sehingga ia jera atau kapok untuk mengulangi kembali perbuatannya. Budaya yang terbentuk di suatu lembaga yang berjalan terus menerus terhadap korupsi dan penyuapan dapat menyebabkan korupsi sebagai hal biasa. Pelaksanaan sistem perdilan pidana, hingga saat ini belum menunjukkan kinerja secara optimal dikarenakan secara struktural tidak bersifat terpadu dalam hal konsep fungsi dan pengawasan dalam manejemen sistem peradilan/penegakan hukum tidak dalam arti luas, lemah dalam penegakan hukum sebab berkedudukan di bawah kekuasaan eksekutif (pemerintah) sehingga dalam hal-hal tertentu pelaksanaan penegakan hukum pidana mendapat pengaruh kekuasaan eksekutif dan tidak menutup kemungkinan pengaruh kekuasaan lainnya, jadi masih belum ada ketegasan mengenai perbedaan antara fungsi eksekutif, yudikatif, dan legislatif.

Kata kunci : Penyidik, Korupsi, Tindak Pidana

AbstractCriminal acts of fraud are currently growing following the times and advances in technology. Legal regulations are made to anticipate this, but the existing regulations do not seem to reduce these crimes but have increased. This study aims to: first, determine law enforcement against criminal acts of fraud based on e-commerce; and second, knowing the inhibiting factors in enforcing criminal law against criminal acts of e-commerce based fraud. The results of the study illustrate that the crime of fraud based on e-commerce is in principle the same as fraud in the conventional way, but the difference lies in the evidence or means of action, namely using electronic systems (computers, internet, telecommunication devices). Therefore law enforcement regarding this crime of fraud should still be accommodated by the Criminal Code through article 378, and to strengthen the legal basis it can also be accommodated through Article 28 paragraph (1) of Law Number 19 of 2016 concerning Information and Electronic Transactions. As a special law (Lex Specialist Derogat Lex Generale), the ITE Law can at least become a guideline and legal basis for members of the public in their activities in cyberspace.

Keywords: Law Enforcement, Transactions, Buying and Selling, Online
BENTUK PERLINDUNGAN HUKUM KEPADA ANAK SEBAGAI KORBAN TINDAK PIDANA KESUSILAAN DALAM HUKUM PIDANA POSITIF SAAT INI
Authors: Farah Andriani  , Msy. Arifah Sumayyah  , Muhammad Ria Revanza  , Fajri Ramadhan  , M. Ivandi Aulia  , Haryadi Tobi
Published: March 2024

AbstrakMasalah tindak pidana asusila terhadap anak muncul karena pelaksanaan hukum pidana tidak berorientasi pada nilai keadilan, terutama pada perlindungan korban, melainkan pada penerapan pemidanaan terhadap pelaku tindak pidana. Akibatnya, tidak menakut-nakuti orang tentang kejahatan kesusilaan, apalagi tentang pemerkosa dan pelecehan seksual anak. Masalah penelitian ini adalah bagaimana ketentuan perlindungan hukum bagi anak yang menjadi korban tindak pidana asusila menurut hokum pidana positif saat ini. Perlindungan hukum terhadap anak korban tindak pidana kesusilaan dalam hukum pidana positif saat ini terdapat pada Pasal 287, 290, 292, 293, 294 dan 295 KUHP dan Pasal 81 dan82, Undang-Undang. Nomor. 23/ 2002 jo. Undang-Undang. Nomor. 35 Tahun 2014jo Perpu No.1/ 2016 tentang Perubahan kedua atas Undang-Undang Nomor. 23/2002 tentang Perlindungan Anak, dan apabila korban termasuk dalam lingkup rumah tangga, maka berlaku juga ketentuan Pasal 46 dan 47 Undang-Undang Nomor 23 / 2004 tentang Penghapusan KDRT, serta Undang-Unang Nomor 31/2014 tentang Perlindungan Saksi dan Korban. kelemahan yang muncul pada Undang-Undang Nomor 31/2014 adalah belum adanya suatu ketentuan yang mengatur sanksi apabila pelaku tidak memberi restitusi bagi korban.

Kata Kunci : Perlindungan Hukum, Anak, Kejahatan Moral.
SOSIALISASI KEBIJAKAN PELAKU USAHA YANG MEMUAT PERLINDUNGAN HAK KETANAKERJAAN PEREMPUAN TERKAIT DENGAN PELAKSANAAN PENGHORMATAN HAK-HAK PEREMPUAN DI PERUSAHAAN
Authors: Nur Aziza  , Fitri Yani  , Diah Syawitri  , Muhammad Fajar Fadillah  , Riko Anggara Putra  , Riviyusnita Rianda
Published: March 2024

AbstrakSesuai amanat Undang-Undang, pekerja perempuan tentunya mendapatkan hak yang sama dengan pekerja laki-laki. Berbagai hal harus diketahui tentang upaya pemerintah dalam memberikan perlindungan bagi pekerja perempuan didalam dunia kerja seiring dengan kebutuhan ekonomi dalam suatu masyarakat. sampai saat ini, pemberi kerja dalam pelaksanaan kewajiban perlindungan bagi tenaga kerja perempuan, masih cukup banyak yang belum melaksanakan secara utuh atas perlindungan tersebut yang mencakup ; istirahat haid, istirahat melahirkan, stirahat gugur kandungan, kesempatan menyusui, juga ilarangan imemperkerjakan itenaga ikerja iperempuan hamil pada kondisi berbahaya dan adanya kewajiban yang menentukan bagi tenaga kerja perempuan yang bekerja dimalam hari. kementrian ketenagakerjaan (kemnaker) menghimbau semua pihak agar semakin mengutamakan perlindungan bagi tenaga kerja perempuan. Sehingga mampu memberikan nilai tambah terhadap reputasi prestise, dan nama baik perusahaan, sebagai entitas yang berkomitmen dalam mewujudkan dunia kerja inklusif, dalam penghormatan asas kesetaraan.

Kata Kunci: Ketenagakerjaan, Hak-Hak Perempuan, Pelaku Usaha.
IMPLEMENTASI BATAL DEMI HUKUM DALAM PERJANJIAN KERJA MENURUT UNDANG-UNDANG NOMOR 13 TAHUN 2003 TENTANG KETENAGAKERJAAN
Authors: Julianto  , Muhammad Abdurrahman  , M. Soheh Salahudin W  , Alvin Reynaldo  , Reggy Permana  , Husnaini Husnaini
Published: March 2024

Abstrak

Hubungan kerja pada dasarnya adalah hubungan antara pekerja/buruh dan pengusaha setelah adanya perjanjian kerja. Perjanjian kerja merupakan awal dimulai suatu hubungan kerja yang dibuat atas pernya taan kesanggupan antara pekerja/buruh dengan pengusaha. Perjanjian kerja dapat dilakukan secara lisan maupun tulisan. bagaimana implementasi makna  batal demi hukum  dalam perjanjian kerja yang bertentangan dengan Undang-Undang Nomor 13 Tahun 2003 Tentang Ketenagakerjaan. Penelitian yang digunakan adalah penelitian hukum normatif yaitu sebuah metode penelitian hukum yang dilakukan dengan meneliti bahan pustaka atau data sekunder. Sumber data sekunder yaitu berupa dokumen-dokumen tertulis, peraturan perundang-undangan dan litelatur-litelatur yang berkaitan dengan objek penelitian ini. Makna batal demi hukum berarti perjanjian kerja tersebuat seolah-olah tidak pernah ada atau sejak semula secara yuridis tidak pernah ada  perjanjian. Namun dalam kenyataan yang sering terjadi walaupun pekerjaaan tersebut  batal demi hukum ada tetapi pekerja atau buruh masih tetap diperkerjakan hingga saatnya terjadilah pemutusan hubungan kerja.

Kata Kunci: Batal Demi Hukum, Perjanjian, Kerja