bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH ALOKASI DANA APBN DAN APBD SEKTOR PERTANIAN TERHADAP PDRB DAN PENYERAPAN TENAGA KERJA PROVINSI KALIMANTAN TIMUR
Authors: Setiawati Erni , Rohmah Siti , Jufenli  , Qolbiy Nurul , Dwi Irsalina Nurulia
Published: February 2021

Pengaruh Alokasi Dana APBN dan APBD Sektor Pertanian Terhadap PDRB Dan Penyerapan Tenaga Kerja Provinsi Kalimantan Timur. Penelitian ini berdasarkan pada Teori Ekonomi Makro tentang Produk Domestik Bruto (PDRB).

Tujuan khusus yang ingin dicapai dalam penelitian ini adalah untuk mengetahui dan menganalisa pengaruh alokasi dana APBN dan APBD Sektor Pertanian terhadap PDRB dan dampaknya terhadap penyerapan tenaga kerja sektor pertanian di Provinsi Kalimantan Timur. Metode analisis data yang digunakan pada penelitian ini adalah analisis data secara kuantitatif dengan menggunakan Model Analisis Jalur (Analyis Path). Model persamaan Regresinya menggunakan model persamaan dua jalur.

Substruktur 1 :  Y1  =  ρY1X1  +  ρY1X2  + e1

Substruktur 2 :  Y2  =  ρY2X1  +  ρY2X2  + ρY2Y1 + e2

Di mana variabel PDRB (Y1) dan jumlah tenaga kerja yang terserap pada sektor pertanian (Y2) sebagai dependent variable, sedangkan alokasi dana APBN (X1) dan alokasi dana APBD (X2) sebagai independent variable atau disebut juga predictor (variabel penjelas).

Hasil penelitian setelah diuji baik secara uji signifikasi maupun uji simultan dan parsial bahwa antara alokasi dana APBN (X1), alokasi dana APBD (X2) dan nilai PDRB (Y1) tidak berpengaruh secara signifikan terhadap penyerapan tenaga kerja di sektor pertanian (Y2)

 

Kata kunci: Analisis Path, APBN, APBD, PDRB
THE REVIEW FOR IMPLEMENTATION OF SIMPLE 3D PRINTERS TO EDUCATIONAL PROCESS
Authors: Peter Marcinko , Martin Kočan
Published: February 2021

Urgency of the research. Interest in this topic is aroused, because students are using 3D modelling programs and they can then print and assemble their models during the lessons and verifying some parameters during printing or compare models after.
Target setting. The main goal is to implement 3D printing with a learning process and to acquaint students with 3D printing technology and materials used in this sector. These printers should be used by students on lessons to create 3D objects. Then students create functional assemblies of these objects. Actual scientific researches and issues analysis. In the past few years there has been rapid use of 3D printing. Many 3D printers have gone through various modifications. This is a modification of the construction site. Various types of printers started to be used, such as Cartesian 3D printers, but also printers that use parallel kinematic structure. Many changes have also been made to the electronic site. Whether they are 8 or 32 bit controllers. Uninvestigated parts of general matters defining. This article focuses on analysis of 3D printers, technology and materials in 3D printing, features and use in the educational process. The research objective. The aim of the research is to design and assembly workplace with 3D printers for educational process. Students at this workplace can experimentally use these printers. In the future, these printers could be upgraded and using the Arduino
or Raspberry Pi system, could measure some of the printer's features directly in the printing process. These electronic components should be used, for example, to measure moisture, which significantly affects the quality of the print and the filament.
The statement of basic materials. The analysis consists of basic information about 3D printer technologies. The definition of this problem is described below. Based on this knowledge and next information about some 3D printers, was chosen one of these.
Conclusions. Our vision is to implement knowledge about 3D printing into the learning process so that students can not only create objects using 3D modelling programs, but also realize this knowledge. This way they will prove 3D technology, which is fast moving nowadays. By further research in this area we would like to set up a 3D centre for these technologies, where other systems would verify the properties of the printing itself.
PROPOSAL OF HANDLING PROCESS ON ROBOTIZED WORKPLACE WITH DUAL ARM ROBOT
Authors: Semjon Ján , Demko Rastislav
Published: February 2021

Urgency of the research. Deployment of two-arm robots in different plants increases production or assembly efficiency. By designing a robotized workstation for assembly we will improve students' competences in the field of robot programming.
By preparing students at robotic workplaces using two-arm robots, we increase their employment in the labor market. Target setting. The aim of the solution is to design an educational workplace for assembly, equipped with a two-arm robot. The object gripper uses Schunk electric grippers to adjust the range of movement and clamping force. This will allow students to create an optimal program according to individual requirements.
Actual scientific researches and issues analysis. The question of the use of collaborative robotics in industry is highly relevant. If two-arm industrial robots are equipped with safety sensors, we can increase the safety of working in collaborative workplaces without using a collaborative robot. Uninvestigated parts of general matters defining. Increasing the skills of students in the programming of industrial robots, improves their possibilities of employment in practice. At the same time, it creates conditions for maintaining the growth of the national economy in the near future. The research objective. The aim of the research was to design a robotic workplace so that students could use a creative approach to solve a given problem. At the same time, the use of the Faculty logo as a model for the proposed assembly preparation will increase the social awareness of the whole university. The statement of basic materials. The deployment of two-arm robots and the preparation of workers for their programming, maintenance and operation will ensure the development of robotics and facilitate manual work. This also leads to an increase in the share of production and deployment of products with higher added value. Conclusions. The article describes the design, production, programming and commissioning of a robotized workplace for educational purposes. The workplace is equipped with a two-arm Yaskawa robot and a pair of Schunk electric grippers. The aim of the work was to design an assembly and dismantling process that would demonstrate the possibilities of working on a two-arm robot. The robotized workstation, when completed, allows the rotary cylinder to be inserted and then removed in a closed loop. Manipulated parts are found in the proposed fixtures, whose shape is based on the university's initial fonts, which make up its logo. Students participating in the learning process will be able to modify the program based on the teacher's assignment and thus improve their robot programming skills.
PROFIL GAYA MANAJEMEN KONFLIK PADA ISTRI YANG BEKERJA DI PERKANTORAN JABODETABEK
Authors: Sari Listia Wulan , Rossalia Nanda , Dewi Zahrasari Lukita
Published: February 2021

Wife who works has more than one role, namely the role of wife for the husband, mother forchildren, as a housekeeper, and as a worker. The many roles and responsibilities make workingwives vulnerable to various kinds of conflicts. If the conflict experienced is not handled properly,it will have the potential to damage the existing relationship. So it becomes important for a workingwife to be able to manage her conflict well. There are five conflict management styles developedby Thomas & Kilmann (2008) based on the dimensions of assertiveness and cooperativeness,namely; Competing, Collaborating, Compromising, Avoiding, and Accomodating. This study useda quantitative method, with 128 participants with the characteristics of a wife, full-time officeworker, age range within 20-40 years old (M= 30.8; SD= 4.88), have children and live in Jakartacity, Bogor city, Depok city, Tangerang city, and Bekasi city (Jabodetabek). Conflict managementstyle is measured using the Thomas-Killman Conflict Mode Instrument (TKI) which is adapted inIndonesian. The results showed that the dominant conflict management style used by the workingwive in Jabodetabek is compromising. As well as the conflict management style that theparticipants have in each demographic category, namely participant age, length of marriage,living with nuclear family vs extended family, monthly range of income and length of work, iscompromising style.
PROSES RESILIENSI PADA REMAJA AKHIR PEREMPUAN YANG PERNAH MENGALAMI BULLYING VERBAL KARENA OBESITAS
Authors: Yunisca Cicilia Ajeng , Wibawa Dhevy Setya
Published: February 2021

Bullying may occur in the form verbal bullying. It often happens in late adolescent girls whosedifferent physical appearance compared to others, such as obesity. Bullying can negatively affectindividuals who experience it, both in long and short period of time. However, with the ability tobounce back from negative situations, an individual can recover from the adverse experiencecaused by verbal bullying. The aim of the study was resilience process using qualitative methodswith homogenous sampling to select the participants. Researcher used semi structured interviewstowards two late adolescent girls aged 18 to 21 years old who experienced verbal bullying becauseof obesity during the middle school (Sekolah Menengah Pertama) and high school (SekolahMenengah Atas). The results showed that two participants experienced negative effects because ofverbal bullying especially in their self-confidence and the ability to develop their skills. Allparticipants could adapt positively by involving protective factors from the environment andinternal resilience factors. Environment factors that helped the participants were from theirparents and friends. Internal factors that helped participants including spirituality, cognitive,physical, social and emotional factors. Both participants showed resilient integration as theirpositive adaptation. This can be seen from the ability to increase environmental resources bydeveloping new social support, increasing internal resources within themselves and developcoping and problem solving skills.
Aspectos metodológicos do levantamento epidemiológico das condições de saúde bucal e qualidade da assistência odontológica entre escolares
Authors: Martins Andréa Maria Eleutério de Barros Lima , Magalhães Amanda Neves , Santos Ana Maria Rodrigues , Alves Fernanda Gonçalves , Antunes Giovana Rafaelly Silva , Coutinho Gisely Cardoso Dourado , Fernandes Henrique Carvalho de Brito , Dos Santos Juliana Pereira , Soares Maria Alice Aguiar , Antunes Tamires Aparecida Ramos
Published: February 2021

Objetivo: Apresentar aspectos metodológicos utilizados para realizar o “Levantamento epidemiológico sobre condições de saúde bucal entre escolares de uma cidade polo de médio porte populacional situada no Norte de Minas Gerais, Brasil” que propõe avaliar as condições da saúde bucal e a qualidade do atendimento odontológico. Métodos: Estudo metodológico referente a criação e validação de instrumentos relacionados à saúde bucal e investigação epidemiológica. Resultados: Foi estimada uma amostra probabilística complexa por conglomerados aleatória simples estratificada (5, 12 e 15 anos). O planejamento incluiu a condução de entrevistas e exames bucais por profissionais calibrados e acadêmicos treinados. Foram avaliadas condições normativas de saúde bucal, condições subjetivas de saúde bucal, assim como o uso e acesso dos serviços, o nível de letramento e a qualidade da assistência odontológica. Conclusão: Com a metodologia descrita será possível obter resultados que favorecem dimensionar a necessidade de ações abrangentes viabilizando melhorias nas estratégias de inclusão dos grupos populacionais mais afetados nas prioridades municipais dos serviços de saúde.
Al Khayal Wal Takhyil fil 'Ashril "abbasy
Authors: Ewida Sherif Abdullhalim Mohamed , Abdullah Ramadan khalaf Morsy  , Elsayed Mohamed Salem
Published: February 2021

الخيال أمر ضروري للإنسان، ولروحه وقلبه وعقله وشعوره، ولا غنى عنه ما دامت الحياة، ولقد حظي التخييل باهتمام عظيم خاصة عند الإبداعيين؛ فعرف مصطلح التخييل قديمًا في المعاجم العربية، وعرف أي ًضا عند الفلاسفة المسلمين واليونان، كما عرفه البلاغيون العرب القدامى كالجرجاني، وأبي هلال العسكري، وحازم القرطاجني. وقد نتج عن امتزاج الثقافات في العصر العباسي أن صارت صور الخيال معقدة؛ فسلك الأدباء والكتاب في ذلك العصر مسالك جديدة أسفرت عن التجديد في التخييل. وقد اكتظت كتب الأدب العباسي بالحكايا والخيالات التي اتسمت بطابع 

النضج الفني. من هنا جاءت هذه الدراسة لإلقاء الضوء على ما وصلت إليه الفنون الأدبية في العصر العباسي من سمو وبهاء،

وتناول مفهوم الخيال لغة واصطلاحا، والوقوف عند بعض الحكايا والخيالات في العصر العباسي وتناولها بشيء من￼￼ التفصيل. وتكمن أهمية هذه الدراسة في أنها تلقي الضوء على الرصيد المعرفي والثقافي للعصر العباسي، مع أخذ عينات من أوائل الكتب التراثية الأدبية التي أبرزت الخيال والتخييل، اعتمادا في ذلك كله على استخدام المنهج الوصفيالتحليلي.
Book Review by Jennifer Clara Tang, University of Western Ontario
Authors: Tang Jennifer Clara
Published: February 2021

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Personalized Medicine: Challenging Pharmaceutical and Diagnostic Company Business Models
Authors: Ferrara Joseph
Published: February 2021

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Emergence of Primary Teeth in Children of Sunsari District of Eastern Nepal
Authors: Gupta Anita , Hiremath SS , Singh SK , Poudyal S , Niraula SR , Baral DD , Singh RK
Published: February 2021

ABSTRACT: This study assessed the timing and eruption sequence of primary teeth in children of Sunsari district of Eastern Nepal and compared the eruption pattern of males & females between various, ethnic groups.

Method: This cross-sectional study, included 501 subjects, aged 3 months to 60 months selected by simple random sampling method. The determinant variables such as age, gender, ethnicity, and eruption of teeth were recorded.

Results: This study provides a model data on emergence of primary teeth and number of deciduous teeth in these children. This is a first study of its kind in Nepal. The findings of this study will help as a reference data for optimal use in clinical, academic, and research activities, especially for children of Eastern Nepal.
Personalized Medicine and the Practice of Medicine in the 21st Century
Authors: Issa Amalia M.
Published: February 2021

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Protein expression of MEF2C during the critical period for visual development in vervet monkeys
Authors: M Bernad Daniel , E Lachance Pascal , Chaudhuri Avijit
Published: February 2021

During the early development of the visual cortex, there is a critical period when neuronal connections are highly sensitive to changes in visual input. Deprivation of visual stimuli during the critical period elicits robust anatomical and physiological rearrangements in the monkey visual cortex and serves as an excellent model for activity-dependent neuroplasticity. DNA microarray experiments were previously performed in our lab to analyze gene expression patterns in area V1 of vervet monkeys subjected to monocular deprivation (MD). An interesting candidate identified in its screen was myocyte enhancer-binding factor 2C (MEF2C), a transcription factor linked to neuronal survival. Consistent with the microarray data, we show that there is a qualitative increase in MEF2C protein expression in area V1 of infant as compared to adult vervet monkeys. Our results suggest that the regulation of neuronal survival is one of the molecular mechanisms underlying the critical period for visual cortical neuroplasticity.
Anterior cruciate ligament reconstruction: a look at prosthetics - past, present and possible future
Authors: Mascarenhas Randy , MacDonald Peter B.
Published: February 2021

ABSTRACT: Biological tissue autograft reconstruction using the patellar tendon or quadrupled semitendinosus/gracilis tendons has become the most popular procedure in surgical treatment of a ruptured ACL. This article provides a review of the history of the use of prosthetics with respect to ACL reconstruction grafts including Carbon Fibre, Gore-Tex and Dacron prosthetics as well as the Leeds-Keio Artificial Ligament and the Kennedy Ligament Augmentation Device (LAD). Emphasis is placed on the Ligament Advanced Reinforcement System (LARS) as preliminary investigations of its use have been encouraging. Significant progress has been made recently with respect to the understanding of ACL anatomy, composition, biomechanics, and healing processes, leading to innovative techniques using approaches based in tissue engineering principles and computer – assisted surgery. While research into improved ACL treatment options continues, the synthesis of recent advancements provides a new optimism towards the regeneration of an ACL mirroring its original stability, function, and longevity.
A forme fruste of Shone’s anomaly in a 65 year-old patient
Authors: Moustafa Sherif E , Lesperance Jacques , Rouleau Jean-Lucien , Gosselin Gilbert
Published: February 2021

Shone’s anomaly, a congenital cardiac malformation complex, consists of multiple levels

of left heart obstruction. A rare case of an incomplete form of this anomaly discovered incidentally

during cardiac catheterization for an unrelated event is described.
Ethics and Current Medical Controversies
Authors: Stefanescu Ada , Zhang Alice Yang , Ge Yin
Published: February 2021

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A clinician’s view of mixed health care in Quebec
Authors: Lapalme-Remis Samuel
Published: February 2021

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The Role of the Placebo in Clinical Practice
Authors: Lichtenberg Pesach
Published: February 2021

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Loud Music Listening
Authors: Petrescu Nicolae
Published: February 2021

Over the past four decades, there has been increasing interest in the effects of music listening on hearing. The purpose of this paper is to review published studies that detail the noise levels, the potential effects (e.g. noise-induced hearing loss), and the perceptions of those affected by music exposure in occupational and non-occupational settings. The review employed Medline, PubMed, PsychINFO, and the World Wide Web to find relevant studies in the scientific literature. Considered in this review are 43 studies concerning the currently most significant occupational sources of highintensity music: rock and pop music playing and employment at music venues, as well as the most significant sources of non-occupational high-intensity music: concerts, dicotheques (clubs), and personal music players. Although all of the activities listed above have the potential for hearing damage, the most serious threat to hearing comes from prolonged exposures to amplified live music (concerts). The review concludes that more research is needed to clarify the hearing loss risks of music exposure from personal music players and that current scientific literature clearly recognizes an unmet hearing health need for more education regarding the risks of loud music exposure and the benefits of wearing hearing protection, for more hearing protection use by those at risk, and for more regulations limiting music intensity levels at music entertainment venues.
A Case Of Atypical Presentation of Thoracic Osteomyelitis & Paraspinal Abscess
Authors: Acharya Utkarsh
Published: February 2021

Here presented is a case involving a 44-year-old man with a chief complaint of sharp lateral right-sided rib pain with notable radiation to the anterior portion of the thorax and minor radiation around the lateral back. The etiology of the pain and radiculopathy, which was initially attributed to a right-sided rib fracture, was later accurately credited to a paraspinal abscess discovered on a lateral X-ray of the thoracic spine. Subsequently, studies including Magnetic Resonance Imaging (MRI), Computed Tomography (CT), and bone scan all confirmed the diagnosis of a paraspinal abscess between the right lobe and its neighboring T9 and T10 vertebrae. The mass was biopsied and methicillin sensitive Staphylococcus aureus was isolated. Appropriate surgical and medical intervention was possible due to the early diagnosis of the abscess.
AN INVITATION TO THE MEDICAL STUDENTS OF THE WORLD TO JOIN THE GLOBAL COALITION TO IMPROVE CARE FOR CHILDREN AND ADULTS WITH CONGENITAL HEART DISEASE ACROSS THE WORLD
Authors: Bernier Pierre-Luc , Ota Noritaka , Tchervenkov Christo I. , Jacobs Jeffrey P. , Stellin Giovanni , Kurosawa Hiromi , Mavroudis Constantine , Cicek Sertac , Al-Halees Zohair , Elliott Martin , Jatene Marcelo , Jonas Richard A. , Kinsley Rob , Kreutzer Christian , Leon-Wyss Juan , Liu Jinfen , Maruszewski Bohdan , Nunn Graham , Ramirez-Marroquin Samuel , Sandaval Nestor , Sano Shunji , Sarris George , Sharma Rajesh , Spray Thomas , Ungerleider Ross , Yangni-Angate Hervé , Ziemer Gerhard
Published: February 2021

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From the Editor’s Desk: Medline and Beyond
Authors: Stefanescu Ada , Yang Zhang Alice , Ge Yin
Published: February 2021

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Adverse Reproductive Outcomes Associated With Teenage Pregnancy
Authors: Yadav Siddhartha , Choudhary Dilip , KC Narayan , Kumar Mandal Rajesh , Sharma Achyut , Singh Chauhan Siddharth , Agrawal Pawan
Published: February 2021

Introduction– It is debated whether teenage pregnancy is associated with an adverse reproductive outcome. This study assessed the reproductive outcomes in teenage pregnancy in Nepal, a developing setting. Methods – Ahospital based retrospective cohort study of 4,101 deliveries to compare the outcomes between teenage and non-teenage pregnancies. Results – Pregnancy in teenagers was associated with significantly increased risk (P<0.05) of delivery of very and moderately preterm births and Low Birth Weight babies. There was no significant difference in risk of having small for gestational age babies, low APGAR score at birth at 1 min and 5min, stillbirth, neonatal death, and post partum hemorrhage. However, the risk of having delivery by episiotomy, vacuum or forceps and Caesarean section was significantly lower (P<0.05) among teenage mothers. Conclusion – Teenage women were more likely to have preterm births and low birth weight babies. However, they were less likely to have delivery by episiotomy, forceps or vacuum and Caesarean sections. In other respects, there were no significant differences between teenage and non-teenage mothers.
Morgagni hernia: Ten years of idiopathic vomiting
Authors: Mustafa Khalil Ahmed A , McMillan Aim M
Published: February 2021

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Jejunal Intussusception as an Unusual Cause of Abdominal Pain in an Adult
Authors: Mehta Rohtesh S.
Published: February 2021

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Read any good books lately?
Authors: Murray T. Jock
Published: February 2021

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Climate Change and Health in Canada
Authors: Ford Lea Berrang
Published: February 2021

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Intermittent Weakness and Mediastinal Weakening
Authors: Malik Umer Feroze , Martin Mersadies R , Pham Hien D , Mahmoud Ahmed , Kapre Sheela
Published: February 2021

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A Perspective on Health Inequities and the Need for Universal Healthcare
Authors: Skolnik Caroline
Published: February 2021

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Anthropology’s Contribution to Public Health Policy development
Authors: Campbell Dave
Published: February 2021

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The Canadian Space Agency Space Learning Grants
Authors: Clement Jason
Published: February 2021

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A Man with a Neck Mass, Pleural Effusion and Hypoechoic Masses in the Right Atrium and Ventricle
Authors: Jalil Rabiya , Rehman Habib ur
Published: February 2021

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Me and my “benign” brain tumor: Musings of a patient
Authors: Rieger Brigitte
Published: February 2021

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An Unusual Case of Resistant Hepatic Hydrothorax Treated with Octreotide Infusion
Authors: Ghahremani-Ghajar, Mehrdad , Tabassomi Mostafa , Harada Scott , Vempilly Jose Joseph
Published: February 2021

Hepatic hydrothorax is an uncommon clinical problem observed inpatients with end stage liver disease and portal hypertension. The pathogenesis of pleural effusion in this condition is thought to involve the movement of ascitic fuid across diaphragmatic defects into pleural cavity facilitated by a negative pleural pressure. Therefore, tube thoracostomy is not considered to be a defnitive treatment option in the management of hepatic hydrothorax. We present a case of massive pleural effusion secondary to hepatic hydrothorax not responding to conventional treatment successfully treated with intravenous infusion of octreotide.
The Difference Between Disease and Illness
Authors: Lach Katherine
Published: February 2021

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Omalizumab Treatment for Severe Atopic Asthma in a Real World Montréal Cohort
Authors: Haile-Meskale David , Olivenstein Ron , Mcgovern Toby , Fugere Cathy , Martin James G.
Published: February 2021

Background: Individuals with severe atopic asthma are poorly controlled with standard treatments, including corticosteroids. A humanized monoclonal antibody binding immunoglobulin E (IgE), omalizumab, is approved to treat patients that are managed poorly despite optimal therapy and that have elevated serum levels of IgE.  Objective: The purpose of this study was to determine omalizumab’s effectiveness in a real-world setting. The primary outcome was the number of exacerbations of asthma requiring oral corticosteroid treatment in the 2 year pre-treatment period compared to 2 years post-treatment. The secondary outcome was cumulative dose of prednisone used before and after treatment. Other outcomes that were measured included: reduction in maintenance therapy, change in spirometry (FEV1) data, the stratification of patient population based on smoking status, and average exacerbation number and prednisone use as a function of IgE level and blood eosinophilia count.   Methods: Patient data were retrieved (n=41) through the hospital records of patients treated at the Montreal Chest Institute of the McGill University Health Center. Data were gathered and analyzed for the 2 years before the treatment start date and compared to data 2 years after.  Results:There was a significant reduction in average exacerbation number from 6.4  pre-treatment to 3.2  post-treatment (p=0.003). There was also a reduction in cumulative prednisone use from 2504mg to 1423mg (p=0.04) following the institution of omalizumab treatment. There was no correlation between either the initial IgE levels and blood eosinophilia and the reduction in exacerbations  Conclusion: Omalizumab was effective in reducing exacerbation number and prednisone use for patients with severe refractory asthma.
Deep Learning: A New Horizon for Personalized Treatment of Depression?
Authors: Benrimoh David , Fratila Robert , Israel Sonia , Perlman Kelly
Published: February 2021

Globally, depression affects 300 million people and is projected be the leading cause of disability by 2030. While different patients are known to benefit from different therapies, there is no principled way for clinicians to predict individual patient responses or side effect profiles. A form of machine learning based on artificial neural networks, deep learning, might be useful for generating a predictive model that could aid in clinical decision making. Such a model’s primary outcomes would be to help clinicians select the most effective treatment plans and mitigate adverse side effects, allowing doctors to provide greater personalized care to a larger number of patients. In this commentary, we discuss the need for personalization of depression treatment and how a deep learning model might be used to construct a clinical decision aid.
Karate Chops and Kitchen Tools: My experience learning new skills alongside youth with special needs at Montreal’s Friendship Circle
Authors: Cipolla Josie
Published: February 2021

As part of our second year in medical school, we are required to seek out a volunteer placement in order to get exposed to the social aspect of medicine, exploring the social determinants of health up-close and personally. This is accomplished through a course called the Community Health Alliance Project (CHAP). My experience at the Friendship Circle of Montreal has opened my eyes to the place that friendship has in caring for an individual. Being a "buddy" to someone with special needs works to undo the isolation and stigmatization that further complicate their unequal access to healthcare and services. Acknowledging that community and companionship are some of the tangible and addressible needs of youth with special needs brings us one step closer to bridging the gap when it comes to accessible health for all.
Delisting Full Coverage for In Vitro Fertilization in Quebec
Authors: De Simone Alexia
Published: February 2021

On 28 November 2015, the Quebec government withdrew full coverage for its assisted procreation program that had been previously covered since 2010. The previously approved legislation under Bill 26 aimed to decrease neonatal intensive-care unit costs associated from multiple birth pregnancies and to increase the number of live-births in the province by funding up to six natural in vitro fertilization (IVF) cycles and implementing a single-embryo-transfer (SET) policy. One factor that contributed to delisting IVF services in Quebec was Quebec’s Commission of Health and Well-Being’s report that concluded that IVF services costed $63 million/per year and resulted in 1300 births/per year. Taken within the larger context of Quebec’s goal to optimize financial ressources within the healthcare system and to reduce the province’s growing debt in 2015, the government withdrew fully-funded IVF services, embryo storage and drug costs and imposed stricter criteria on who could access IVF based on a woman’s age. The government provided tax credits based on a person/couples income, again based on specific criteria. Since implementation of Bill 20, IVF rates have dropped dramatically within the province and multiple-birth pregnancies are on the rise once more. Ultimately, while delisting IVF services in Quebec provided cost-savings in the province’s budget, the law poses serious setbackts to individuals that cannot afford out-of-pocket payments and raises ethical concerns regarding infertility as a medical condition. The newly elected government in 2018 is currently studying the possibility of reinstating full coverage of oneIVF cycle by 2020.
Healing starts with understanding: Addressing language barriers in patient care through medical student interpreters
Authors: Ji Xinyu , Abdelhamid Kenzy , Naumova Darya , Chow Ellen , Chirgwin Juan-Carlos
Published: February 2021

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Perceived reproductive health needs among Muslim women in the southern US
Authors: Eksheir Sondous , Bowling Jessamyn
Published: February 2021

Despite growing rates of Muslims in the United States, we know little about the health of Muslim women in this country. Due to the stigma surrounding sex, sexuality, and the cultural beliefs of this population, there may be unique and unknown challenges regarding access to reproductive health care for Muslims in the US. Purpose: This study aims to examine variables that promote and impede access to reproductive health care for Muslim women in the southern US. Methods: This multi-method study included in-person semi-structured interviews (n=15) and an anonymous online survey (n=76). Findings: Participants generally had low rates of gynecological care and cervical cancer screening. The cultural (e.g. waiting for marriage to receive gynecological care) and contextual aspects (e.g. gender) that increased or restricted access to care in terms of screening, providers and education are discussed. We also identified some misconceptions related to screening and contraception. Conclusions: Influences on reproductive health care experienced by participants in this study have similarities yet are distinct from Muslim populations in other countries as well as other groups of women in the US. This study points to a need for more population-focused education of providers, as well as awareness about reproductive health and health care recommendations and access for Muslim women.
Role of Medical Students in Responding To COVID-19: Identifying and Addressing Vital Deficiencies
Authors: Maizlin Nick N. , Farrokhi Kaveh , Ding Mike
Published: February 2021

To address the shortage of personal protective equipment (PPE) that occurred as a result of Coronavirus disease 2019 (COVID-19), three first-year medical students at Western University developed an initiative to deliver handmade gowns to primary care providers in London, Ontario, Canada. They partnered with the local branch of the Canada Sews organization to sew the gowns, and created a gown order form which was distributed in the community. Following gown delivery by the authors, an optional feedback form was sent to the gown recipients for quality assurance purposes. As of June 10, 2020, 411 gowns were delivered to medical and dental locations, long-term care homes, emergency shelters, and pharmacies. Feedback from the recipients indicated that the gowns were comfortable to wear and consistently useful to primary care practices. The successful execution of the initiative within a month of its inception, the delivery of more than 400 gowns within the subsequent month, and the positive feedback from the gown recipients, indicates that medical students can play an important role during the COVID-19 pandemic, and other periods of crisis, even outside of clinical settings. Specifically, they are able to demonstrate the qualities of leadership, collaboration, and advocacy to spearhead initiatives to fulfill unmet community needs. They are also uniquely situated to help their communities due to factors such as the skills and knowledge they have attained in their academic training. Thus, the ability of medical students to assist primary care providers should be taken into consideration for future pandemics.
Penetrating Cardiac Trauma
Authors: L. Mayo George
Published: February 2021

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Effect of Physical Training on the Activity of the Low Km Phosphodiesterase in Heart Ventricular and Skeletal Muscle Tissues of Normal and Diabetic Rats
Authors: Plourde Gilles , Nadeau André
Published: February 2021

This study assessed the effect of physical training on the low Michaelis constant cyclic AMP phosphodiesterase (low Km PDE) activity in heart ventricular tissue and three different skeletal muscle tissues of normal and diabetic rats. Rats were rendered diabetic with streptozotocin (45 mg/kg i.v.) and either kept sedentary (SD, n=16) or submitted to a progressive 10-week treadmill running program (TD, n=17). Two groups of nondiabetic rats served as trained (TC, n=17) and sedentary controls (SC, n=15). The activity of NAD-linked isocitrate dehydrogenase was significantly increased (p < 0.001) in the gastrocnemius muscle of trained animals, confirming that they were adequately trained. Plasma glucose levels were elevated in SD rats (18.8 ± 1.7 mmol/l) compared to those in SC rats (7.7 ± 0.2 mmol/l ; mean ± standard error of the mean [SEM], p < 0.001). These levels were partially normalized following training (12.7 ± 1.7 pmol/l; p < 0.01 vs. SD rats). Plasma insulin levels were significantly reduced in TC rats (223 ± 16 pmol/l) compared with those in SC rats (306 ± 13 pmol/l; p < 0.01). Similarly, the levels in SC rats were significantly different when compared with SD rats (155 ± 15 pmol/l; p < 0.01). In TD rats, plasma insulin levels (156 ± 14 pmol/l) were similar to those of SD rats. This suggests that mild diabetes mellitus in the rat can be improved by endurance training and that improved glycemic control may be mediated by an increase in insulin sensitivity. The low Km PDE activity in the membranes prepared from the four different muscle tissues was not modified by diabetes. Similarly, physical training in normal and diabetic rats did not induce any significant changes in the low Km PDE activity in any of the tissues tested. This suggests that improvements in myocardial contractile function and in glucose homeostasis, as seen in diabetic rats submitted to endurance training, are not associated with changes in PDE.
An Affirmation Of Our Commitment To Student Medical Research
Authors: Lim Jonathan E.
Published: February 2021

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Intraoperative Myocardial Protection: Where Are We Going in the Future?
Authors: Khan Shawn J. , Panos Anthony L. , Salerno Tomas A.
Published: February 2021

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PAVING NEW PATHS TOWARD MEDICAL DISCOVERY: THE SECOND GENERATION OF THE MJM
Authors: Goldenberg Neil A.
Published: February 2021

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Scientific Inquiry, the MJM, and Tomorrow's Physician-scientist
Authors: Goldenberg Neil A.
Published: February 2021

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The Carcinoembryonic Antigen (CEA): Past, Present, and Future
Authors: Gold Phil , Goldberg Neil
Published: February 2021

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Case Report: Carcinoembryonic Antigen (CEA) in Postoperative Follow-up and Treatment Monitoring of Colorectal Adenocarcinoma
Authors: Price Kursteen , Thompson David
Published: February 2021

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Vitamin B12 Inhibits Progression of Hypercholesterolemia and Atherosclerosis in Rabbits Fed a High Cholesterol Diet
Authors: Abou-Khalil Salim , Poulsen Ron , Stemerman Michael B. , Moore Sean , Alavi Misbahuddin Zafar
Published: February 2021

The present study was undertaken to examine the effect of vitamin B12 on serum cholesterol levels and development of aortic atherosclerosis in New Zealand White male rabbits fed a high cholesterol diet. Twenty rabbits were divided into 4 groups matched for their baseline serum cholesterol values. Groups 1 and 2 received a normal diet, whereas groups 3 and 4 had cholesterol mixed with their chow. After 5 weeks, the serum cholesterol of groups 3 and 4 increased by approximately 12 fold compared to groups 1 and 2. At that point, vitamin B12 was administered in the drinking water (1000 micrograms/l) to rabbits in groups 2 and 4. At week 8, the Vitamin B12 dose was increased to 2400 micrograms/l for group 4. At 12 weeks into the study, rabbits in group 4 (high cholesterol diet plus vitamin B12) had a serum cholesterol level of 919 +/- 270 mg/dl while those of group 3 (high cholesterol diet) had a serum cholesterol level of 1417 +/- 250 mg/dl. At the end of the study, rabbit aortas were excised, fixed, and stained with fat-red-B, a dye for lipid. Comparison of the aortas of rabbits that received the lipid rich diet revealed that animals given additional vitamin B12 had significantly decreased surface area of fat deposition. These data suggest the potential role for vitamin B12 as a safe and inexpensive pharmacological intervention for the modification of the progression of human atherosclerosis.
CA 125: History, Current Status, and Future Prospects
Authors: Bast Robert C., Jr , Knapp Robert C.
Published: February 2021

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Cochlear and Auditory Brainstem Implants in the Management of Acoustic Neuroma and Bilateral Acoustic Neurofibromatosis
Authors: Davis Neil L , Rappaport Jamie M , MacDougall James C
Published: February 2021

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Letter from the Dean of Medicine of McGill University
Authors: Fuks Abraham
Published: February 2021

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Relationship of Mental Health to Religiosity
Authors: Glenn Christina L.
Published: February 2021

The purpose of the present study was to examine the question of whether or not commitment to religious beliefs is associated with better mental health in typical community members. A household interview survey was conducted in a stratified, clustered sample of 3% of the adults that resided in a largely religious and rural mountain community. The Duke Health Profile was used to assess mental and physical health, and the nature and depth of religious devotion or commitment was based on the response to an interview item. Of the respondents in the sample, the mean age was 48.7 years, 55% were women, and the average annual family income was $14 300 (US). In a simple unadjusted analysis, religiosity was significantly correlated with physical health (the ill were more religious) and gender (women were more religious), but not with mental health, age, income, education level, or geographic mobility. Mental health was correlated with gender (women scored lower), physical health (the ill scored lower), and income (the wealthy scored higher); but the correlations with these variables were largely in the opposite direction than religiosity. When the correlation between religiosity and mental health were adjusted for the economic, health, and demographic characteristics with the multiple partial correlation method, a definite correlation was found (r = 0.11 to 0.14, p = 0.005 to 0.032). The conclusion is drawn that there is an association between religious commitment and good mental health, but that it can be masked by the inverse dependencies of religion and mental health on economic, health and demographic factors. These results suggest that further investigation should be undertaken in order to elucidate the clinical utility of incorporating religious beliefs and practice into patient therapy.
Congratulations to the MJM from the Pharmaceutical Manufacturers Association of Canada
Authors: Erola J.A.
Published: February 2021

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Being a Medical Scientist: It Takes Love and Dedication to Research, Not a Title
Authors: Franco Eduardo
Published: February 2021

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Congratulations from the Editor of the McGill Medical Journal (1942)
Authors: Stevenson Ian
Published: February 2021

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HIV in the Developing World - Meeting the Challenge of the Growing Dichotomy
Authors: Rao Bhargavi
Published: February 2021

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Congratulations to the MJM from the Dean of Medicine, McGill University
Authors: Fuks Abraham
Published: February 2021

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Progressive Limb Weakness and Sensory Loss in a Young Woman
Authors: Glass Hannah , Srour Myriam , Pari Giovanna , Karpati George , Snipes G. Jackson
Published: February 2021

Patients with neuromuscular disease often present with a combination of symptoms that suggest a wide differential diagnosis. Traditionally, electrophysiologic studies and microscopy have aided the clinician in making a diagnosis. More recently, genetic testing for specific diseases has helped to ensure correct diagnosis. The following is a case that emphasizes the importance of combining clinical, electrophysiologic, microscopic and finally, genetic findings.
Tropical Disease, the Hydra Technology Will Not Slay
Authors: Grant Jennifer M
Published: February 2021

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A Historical Overview of Space Medicine
Authors: Williams David R.
Published: February 2021

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An Old Question Revisited: Current Understanding of Aging Theories
Authors: Wong Tak Pan
Published: February 2021

“Why we age” is no longer a solely philosophical question. In parallel with the risingawareness of the social ramifications of an aging population, basic research has expanded our understanding of the intricate nature of biological aging. The present paper aims at discussing our current understanding of the molecular and cellular alterations that accompany aging. To this end, the main theories on the mechanisms of aging, error theories and program theories, will be discussed. Special focus on neuronal aging is also presented to provide illustrative examples of these aging mechanisms.
Hailey-Hailey Disease (Benign Familial Pemphigus): Carbon Dioxide Laser Therapy
Authors: Freiman Anatoli , Jakim Miriam D. , Billick Robin C.
Published: February 2021

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Isoniazid, The Frontline of Resistance in Mycobacterium tuberculosis
Authors: Whitney James B. , Wainberg Mark A.
Published: February 2021

Tuberculosis is an ancient disease that has held close association with humans for millennia. Through persistence, this remarkably successful organism has managed to infect an estimated third of the world's population. Declining rates of tuberculosis in developed nations have masked an emerging epidemic of drug resistant cases that have been reported in almost every country under scrutiny. The recent completion of the genome sequence of Mycobacterium tuberculosis has mandated more efficient control and management of this disease. The momentum for this public health imperative will come from information gleaned from advances in genomics and related technologies towards deciphering molecular mechanisms of mycobacterial drug resistance.
Book Review: The Human Immunodeficiency Virus: Biology, Immunology, and Therapy
Authors: Whitney James
Published: February 2021

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Fourteenth European Students Conference
Authors: Züfle N. , Ledenig N. , Blaum W. , Schuster A. , Gómez-Carrillo A. , Kötter A. , Ufer F. , Herrmann S.
Published: February 2021

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The MJM: An opportunity for international student collaboration
Authors: Athiviraham Aravind , Labos Christopher
Published: February 2021

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A MEETING OF THE MINDS
Authors: Levitt Randy
Published: February 2021

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A MIDSUMMER DREAM
Authors: Lin Charles C.H.
Published: February 2021

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A MORE OBJECTIVE APPROACH FOR SELECTING THE JOURNAL TO WHICH ONE SUBMITS A MANUSCRIPT
Authors: Mariotto Aldo , Frank Erica
Published: February 2021

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Sub-clinical levels of attention deficit-hyperactivity disorder are associated with tobacco consumption in male but not in female smokers
Authors: Douglas Rebecca L. , Barrett Sean P. , Hanley Neil T. , Pihl Robert O.
Published: February 2021

An abudance of evidence has demonstrated an association between symptoms of attention deficit hyperactivity disorder (ADHD) and tobacco consumption. However, previous research has focused solely on populations meeting full diagnostic criteria for ADHD, despite evidence suggesting that symptoms below diagnostic threshold can be associated with impairment. Furthermore, the role of gender in the relationship between ADHD symptoms and tobacco consumption has not been determined. To examine the relationship between ADHD symptoms, tobacco use, and gender in a non-clinical population, symptoms of inattention, hyperactivity and impulsivity were assessed in 230 undergraduate students (22 male and 45 female smokers, and 66 male and 97 female nonsmokers). Overall, relative to nonsmokers, the smoking subjects reported significantly higher levels of inattention and hyperactivity. In male smokers, both inattentive and hyperactive/impulsive symptoms were positively associated with the number of cigarettes smoked daily. This relationship did not hold for female smokers, for whom no association was found between symptoms and nicotine consumption. Findings imply that even sub-clinical levels of inattention and hyperactivity/impulsivity are related to indices of tobacco use in males, and support previous research suggesting that significant gender differences may exist in tobacco smoking motives. Results also have potential implications for tobacco cessation programs, which may require more individual tailoring.l glutamic pyruvic transaminase is identified in an elderly subject.
Risk Factors for Tuberculosis Conversion in a State Prison
Authors: Hung Robert , Shelton Steven , Rischitelli Gary
Published: February 2021

A case-control study determined the risk factors for latent tuberculosis (TB) conversion among Oregon Department of Correction (ODOC) inmates from July 2000 - July 2001. The first objective was to identity the converters. These were inmates who tested negative for the Purified Protein Derivative (PPD) skin test on entry and subsequently tested positive on annual testing. The second objective was determining the risk factors for conversion by comparing the converters with randomly selected controls. The Correctional Information System (CIS) and Mental Health databases were accessed to obtain health and demographic information. With ninety-nine percent of PPD positive inmates on anti-tuberculosis medications, nearly all male inmates who tested positive from July 00-01 (n = 307) were identified through the ODOC pharmacy records. A medical chart review (276 of 307 or 90%) separated the converters (n = 72) from the reactors who tested positive on entry (n = 123) and the prior positives on medications (n = 81). The conversion rate was 5.0 per 1,000 person-years. Differences between the cases (converters) and controls were analyzed using multivariate logistic regression. The converters were 6 times more likely to be Latino (p < .005) vs. Caucasian, over 19 times less likely to live in medium vs. minimum (p < .001) or maximum vs. minimum (p < .001) security prisons, and over 5 times less likely to live in a medium vs. low (.012 < p < .031) or high vs. low (.002 < p < .007) density prison. They had 1.4-1.5 times fewer PPD skin tests (.002 < p < .009) and lived in 1.5-1.7 times fewer prisons (.005 < p < .017). Age, education, county of incarceration, number of incarcerations, and number of visitors were not found to be significant variables. The results revealed a low conversion rate compared to other U.S. prisons. Prison health officials should consider performing two-step skin testing in order to distinguish the booster phenomenon from intramural conversion.