bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental evaluation of the effect of supplementary nutrition and glutargine on regenerative properties
Authors: Kushta A.A. , Shuvalov S.M.
Published: April 2023

The problem of alimentary dystrophy, which develops due to various reasons, is an urgent problem, especially in patients with tumors of the head and neck. After removal of tumors, patients have large postoperative defects that interfere with proper nutrition. Therefore, to provide the body with the necessary nutrients, enteral nutrition is especially important. In addition, successful wound healing requires adequate blood supply and sufficient levels of nutrients, which depends on the general condition of the body and the patient's diet. However, the degree of reparative processes correlates not only with the number of substrates of anabolism, but also with the proper functioning of the liver. The aim of our study was to investigate the effect of the drug for enteral nutrition and glutargin on the reparative properties of rats’ wounds on the background of partial food deprivation. The study was performed on 60 adult male rats weighing 280±20 grams of the Wistar line, with a mean age of 15 weeks. Prior to the experimental study the regenerative properties of the animals were on partial food deprivation. On the 10th day, a wound with a diameter of 2.0 cm was inflicted. Then the rats were divided into 4 groups: 1 group (control) received food according to physiological needs; Group 2 (food derivation (FD)); Group 3 (FD+enteral nutrition); Group 4 (FD+enteral nutrition +glutargin). Against the background of alimentary dystrophy (20% weight loss) on the first day there was a significant difference in the edges of the wound due to loss of its elasticity. Wound contraction processes up to 14-15 days in all observation groups were quite active, regardless of the factors of malnutrition with cereals or additional therapeutic diet "Peptamen" or in combination with glutargin. Thus, every three days the area of wounds decreased by 30-40 mm2 on an average. Only on the 15th-17th day the difference in the rate of wound contraction becomes visible and statistically significant. Thus, on the 15th day the largest wounds were in the second group on the background of partial food deprivation (p<0.05), at the same time in the first (control) and in the fourth groups the average area was almost equal (p>0.05). The smallest (p<0.05) area of wounds was observed in the first group (control) on the 15th day. On the 17th day wound healing was observed in the fourth group (FD+enteral nutrition+glutargin), despite the expansion of wounds on the first day. A pronounced therapeutic effect correcting alimentary dystrophy was obtained with enteral nutrition (Peptamen) and glutargin at a dose of 50 mg/kg, where the wounds healed simultaneously with those in the first (control) group, ie in animals with a normal diet, indicating a high effectiveness of the proposed method of correction of alimentary dystrophy. Enteral nutrition alone (Peptamen) was also effective, as evidenced by the small size of virtually epithelialized wounds on the 17th day.
Morphological changes of liver and spleen under the impact of dextran-polyacrylamide polymers and their effects as carriers of silver and gold nanoparticles
Authors: Kaleinikova О.М. , Kurovska V.О. , Byelinska І.V. , Kutsevol N.V. , Blashkiv Т.V.
Published: April 2023

The possibility of usage of polymer nanocomposites is being intensively studied today with a purpose of their application in medicine, espessialy in oncology. At the experimental stage it is important to determine the mechanisms of the influence of such compounds on the body and their own possible undesirable effects. Aim – to study the effect of the treatment with maximal doses of the dextran-polyacrylamide polymers and their effect as carriers of silver and gold nanoparticles on the spleen and liver. Histological examination of micropreparations of the spleen and liver by the standard method with hematoxylin-eosin staining was made. As a result of the treatment with nonionic (D-g-PAA) and anionic (D-g-PAA (PE)) polymer matrices, changes which occurred in the spleen indicate an increase in the production of all blood cells. These phenomena were absent when silver and gold nanoparticles were included in the matrix. In the liver, treatment with D-g-PAA and D-g-PAA (PE) caused a disorder of hepatic circulation, focal infiltration by inflammatory cells and death of hepatocytes by necrosis. The addition of nanoparticles triggered other mechanisms of alteration, which manifested themselves in excessive accumulation of glycogen, fatty infiltration of hepatocytes, and cell death, mainly through apoptosis. However, along with this, signs of an incomplete regenerative response of the liver were revealed. Morphological changes caused by the treatment with maximal doses of the tested substances indicate their toxic effect, especially on the liver. Further researches are needed to establish the optimal doses and the frequency of their administration, which can be used for therapeutic purposes, including the interaction of studied polymers with blood cells.
The benefits of coordinated rehabilitation in the treatment of stroke patients: A literature review
Authors: Shuranova L. , Vacková J. , Míková M.
Published: April 2023

The article reveals the features of coordinated rehabilitation – a process that leads to rehabilitating of people with neurological damage that limits their functionality. The purpose of the article is a literature review within the framework of GAJU 066/2022/S, funded by the grant agency of the South Bohemian University of Czech Budejovice, Czech Republic, examining the effectiveness of coordinated rehabilitation in patients recovering from strokes and the use of the standardized Functional Independence Measure (FIM) test to assess the patient’s condition. Data come from current Czech and foreign publications. The EDS multi-finder was used to search for literary sources. Document searches were from 2016-2022 in Czech and English. Search terms include post-stroke rehabilitation, FIM, rehabilitation after stroke, neurorehabilitation, and community based rehabilitation. The start of coordinated rehabilitation of stroke patients should be timely, long-term, comprehensive, and effective, involving a multidisciplinary approach and teamwork. It is essential to develop an individual approach and create a suitable individual plan that allows the use of the FIM test. This is the only way to establish long-term and mutually beneficial cooperation. As the cost of rehabilitation increases, the financial burden on the healthcare system also increases. Caring for a stroke patient also puts various burdens on the family. Successful rehabilitation can reduce the use of costly medicines and materials and decrease the need for nursing care and the term of hospital stay. The social costs of strokes are associated with long-term dependence and a low degree of resocialization. Considering the frequency of strokes and the associated disability, there is an increasing need for coordinated services within coordinated rehabilitation. Gaps in data on coordinated stroke rehabilitation should be filled by providing necessary information about long-term participation in community-based programs.
Pharmacogenetic substantiation of personalized prescription of oral anticoagulants in clinical practice
Authors: Bentsionova K.I. , Rossokha Z.I. , Ievseienkova O.G. , Gorovenko N.G.
Published: April 2023

Thromboembolic diseases are of great clinical concern because of their high prevalence and consequences, which are often fatal. Despite significant progress in the prevention and treatment of thrombotic events, patients remain at risk of life-threatening bleeding episodes and other side effects arising from anticoagulant therapy, so the issue of personalizing prescriptions taking into account the genetic characteristics of patients has become urgent. The purpose of the study is to substantiate the need for patient genotype analysis in order to increase the effectiveness and safety of individual pharmacotherapy. The article has a conceptual nature, therefore the following research methods were chosen: systematization and generalization; analysis and specification; abstract and logical. For the search, we used PubMed, PubMedCentral, Google Scholar, dbSNP, Elsevier, Springer from September 2000 to November 2022. The review included studies written in English and Ukrainian. There were analyzed literature data on two main subclasses of oral antithrombotic agents, including oral anticoagulants and antiplatelet agents, namely warfarin, apixaban, rivaroxaban, and clopidogrel. Prognostically significant for evaluating the effectiveness and safety of anticoagulant use, as well as the most studied in this aspect, are CYP2C9 (rs1799853, rs1057910), CYP2C19 (rs4244285, rs4986893, rs12248560), VKORC1 (rs9923231, rs7294, rs9934438), MDR1 (rs4148738, rs2032582, rs1045642), FGB (rs1800787), PAI-1 (rs1799889) genes. The results of CYP2B6, CYP3A4/5 (rs776746), CYP4F2 (rs2108622) genes analysis indicate a certain influence on the anticoagulants metabolism and require further detailed study. Factors such as age, race, sex, smoking, diet, and other medications are known to influence the effectiveness of antithrombotic therapy, but the most influential factor is genetics, which accounts a significant percentage of interindividual variability. Future research should focus on the study of known and novel genetic variants that influence drug metabolism, as well as the molecular mechanisms that contribute to changes in plasma anticoagulant levels. The article provides a brief overview of action mechanisms, pharmacogenetics, and interactions between drugs and the genes responsible for their metabolism. The results indicate the need for studies of gene variants considered in this review before starting anticoagulant therapy, and attention should also be paid to the possibility of inhibitors and inductors influence on components of the metabolic pathway of anticoagulants and gene expression products that participate in their metabolism. The totality of these measures will ensure an increase in the efficiency and safety of individual pharmacotherapy and allow optimizing the choice and dosage of anticoagulants.
Vascular cell adhesion molecule‑1 levels in patients with coronary artery disease with type 2 diabetes mellitus
Authors: Serik S.A. , Mavrycheva N.R.
Published: April 2023

Chronic systemic inflammation is a key component of the pathogenesis of both type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD). Soluble vascular cell adhesion molecule‑1 (sVCAM‑1) is considered as the indicator of vascular inflammation and endothelial activation. The aim of our study was to investigate sVCAM‑1 levels in patients with CAD with T2DM and to determine their dependence on a previous history of myocardial infarction (MI). The study included 52 patients with stable CAD with T2DM, 20 CAD patients without diabetes and 14 control group persons. sVCAM-1 levels were measured in serum by the enzyme-linked immunosorbent assay. sVCAM‑1 levels in patients with CAD with T2DM and patients with CAD without diabetes were higher than in the control group (p<0,001 and p<0,001, respectively). The difference in sVCAM‑1 levels between CAD patients with T2DM and without diabetes was not significant (p=0,355). There were no significant correlations of sVCAM‑1 levels with glucometabolic indices in any group. Only in patients with CAD with T2DM sVCAM‑1 level negatively correlated with high-density lipoprotein cholesterol. CAD patients with and without T2DM with a history of myocardial infarction (MI) had higher sVCAM‑1 levels than patients without previous MI (p=0,038, р=0,043, respectively). Only in diabetic CAD patients sVCAM‑1 levels were increased in those without a history of MI (р=0,036, in comparison with the controls). There were no correlations between sVCAM‑1 levels and left ventricular remodeling indices in patients either with or without MI. Conclusions. In patients with CAD with T2DM and patients with CAD without T2DM, sVCAM‑1 levels increased in comparison with the controls. However, in patients without diabetes sVCAM‑1 level was increased only in those with previous MI. In patients with T2DM, sVCAM‑1 level increased in the absence of previous MI and there was the further significant increase of its level in postinfarction cardiosclerosis.
Modern approach to infusion therapy of pregnant women with gestational hypertension
Authors: Vaskiv O.V. , Grigorenko A.P. , Gorbatyuk O.G. , Shatkovska A.S. , Binkovska A.M. , Priymak I.A.
Published: April 2023

To date, there are no effective treatment for placental dysfunction in pregnant women with gestational hypertension. Therefore, the purpose of our study was to investigate the clinical efficacy of proposed method of infusion therapy for pregnant women with gestational hypertension, which included a complex of drugs: pentoxifylline, arginine hydrochloride with levocarnitine and rheosorbilact. We observed 73 pregnant women with single fetation, starting from 28 weeks of gestation, who were observed before and during childbirth, and in the postpartum period by the time of discharge from the hospital. All examined women were divided into 3 groups. The first group included 30 pregnant women with gestational hypertension, who received (along with the basic therapy of methyldopa drugs) a complex of infusion solutions: pentoxifylline 0.05% – 100 ml; solution containing arginine hydrochloride 4.2% and levocarnitine 2.0% – 100 ml; reosorbilact preparation – 100 ml. The infusion was carried out once a day in the specified sequence for 10 days. The second group included 20 patients with gestational hypertension on basic therapy with methuldopa only. The control group included 23 women with physiological pregnancy. The data of our study show that in patients receiving the proposed infusion therapy there was a significant decrease in the development of placental dysfunction by 38.3%, the threat of premature birth – by 18.3% and fetal distress – by 30.0%, premature rupture of the membranes – by 35.0%, weakness of labor – by 28.3%, a decrease in the risk of perinatal central nervous system damage – by 33.3% and the frequency of cephalohematomas – by 30.0% compared with women who received only antihypertensive therapy.
The significance of assessment the relationship between the level of 25-(OH) vitamin D and excessive body weight in women on preconceptional period and during pregnancy
Authors: Maksymenko L.R. , Perkhulyn O.M. , Drohomyretska N.V. , Henyk N.I.
Published: April 2023

The goal of this study was to determine the association between the level of 25-(OH) vitamin D and excessive body weight in women on preconceptional period and during gestation. There were studied 117 women. The first group included 68 overweight women (body mass index (BMI) 25.0-29.9 kg/m2), the second – 49 with normal body weight (BMI 18.5-24.9 kg/m2) before prepregnancy. Anthropometry was performed, BMI (kg/m2) by Quetelet formula. The 25-(OH) vitamin D blood serum level was studied by immunoenzymatic method. Fasting blood serum levels of glucose, insulin were determined by the immunoenzymatic method, insulin resistance index was calculated, serum concentrations of triglycerides, total cholesterol, high, low and very low density lipoproteins were determined. The results were statistically analyzed using Statistica 10 (Serial Number: STA999K347150-W) and MEDCALC®. It was found an inverse correlation between the level of vitamin D and BMI (r= – 0.71, p<0.001). Excessive body weight on precon­ceptional period reduces the chances of an adequate level of vitamin D (0.02; 0.00-0.10; p<0.001) and increases the chances of its deficiency (13.11; 4.89-35.30; p<0.001) during early gestational period. It was diagnosed that during pregnancy, the chances of vitamin D deficiency increase in women with normal body weight (3.16; 1.11-9.02; p=0.04), but remain significantly higher in the overweight (6.30; 2.80-14.18; p<0.001). It was shown that insufficiency/deficiency of vitamin D during pregnancy was accompanied by insulin resistance, hyper/dyslipidemia, which are the metabolic basis of gestational complications. The assessment of an inverse relationship between the level of 25-(OH) vitamin D and excessive body weight in women on preconceptional period and the increase of deficiency during pregnancy should be taken into account for the purpose of laboratory determination of the vitamin at the stage of pregnancy planning for the appointment of therapeutic correction.
Correlation between resilience and cognitive functioning in veterans with traumatic brain injury
Authors: Assonov D.O.
Published: April 2023

Resilience in veterans with brain trauma in remote period has received considerable attention over the past years. Cognitive functioning is described among factors that may influence resilience and included in the modern theoretical models of this positive psychology phenomenon. However, the characteristics of relationship between resilience and cognitive functioning in veterans with traumatic brain injury (TBI) in remote period was not studied empirically. Therefore, the purpose of this study was to gain better understanding of the possible association between resilience and cognitive functioning in Ukrainian war veterans with traumatic brain injury in remote period. This study included 146 veterans who were admitted to two clinical hospitals for war veterans. The Connor-Davidson Resilience Scale and Montreal Cognitive Assessment Scale were used. The present study shows that lower cognitive functioning in total and in several domains is associated with less effective resilience regardless of TBI clinical type (whether it is concussion or mild cerebral contusion). Moreover, such correlation was still present after excluding the effect of age, education and TBI characteristics like number of traumas and time since last TBI.  Overall, we found empirical evidence that good cognitive functioning (especially executive functions, memory, attention, abstract thinking, and orientation) is essential for effective resilience in veterans with mild TBI even years after trauma and has more effect on ability to adapt than age, education, and trauma characteristics. Educating veterans to use their cognitive potential and to compensate the restrictions after mild TBI possibly may lead to better overcoming adversities and counteracting the risks of des­adaptation and traumatic events. Therefore, psychological interventions for improving the ability to readapt and recover possibly should consider this relationship and include the component of educating veterans to use their cognitive reserve and compensate limitations to better adapt and thrive. Studies related to such interventions appear to be promising.
Assessment of correlation relationships between the level of mortality of the population of Zhytomyr region of Ukraine from non-infectious diseases and sanitary-chemical indicators of safety and quality of drinking water
Authors: Zablotska О.S. , Кyrytchuk І.M. , Shcherba N.S. , Nikolaieva І.М.
Published: April 2023

The purpose of the publication was to assess the strength and direction of correlation relationships between mortality rates from non-communicable diseases of the population of Zhytomyr region of Ukraine and sanitary-chemical indicators of safety and quality of drinking water. The need for this study was determined by the necessity to adjust existing and develop new strategic approaches to the prevention of non-communicable diseases that depend on the level of chemical contamination of drinking water. The study was conducted in 2016-2020. Standardized indicators of mortality from non-communicable diseases (per 100,000 population) were analyzed. 25375 water samples were studied, among them 8339 belonged to centralized and 17036 – to decentralized water supply. The strength and direction of correlation relationships between population mortality rates from non-communicable diseases and the average values of sanitary-chemical indicators of drinking water were determined by Pearson's linear correlation coefficients and the Chaddock scale. The statistical significance of the correlation coefficients was determined by Student's t-test. In the process of research work such methods as: bibliographic, medical and sociological, retrospective, epidemiological, statistical, system analysis and generalization were used. Statistically significant (p˂0.05) strong direct correlations were found between mortality rates of the urban population of Zhytomyr region from diseases of the circulatory system (I00-I99) (including myocardial infarction) (I21-I22), coronary heart disease (I20-I25), of digestive organs (K00-K93) and average total iron and total hardness values; between nervous system diseases (G00-G99) and average values of manganese in drinking water of centralized water supply, as well as between mortality rates of rural population from diseases of the circulatory system (I00-I99) and average values of total hardness, total iron and nitrates in drinking water of decentralized water supply. The urgent need to develop new strategic approaches to improve the quality of drinking water in the region as one of the factors in the prevention of non-communicable diseases has been proved.
Assessment of potential hazard for humans when eating apples and grapes treated with insecticide based on spiromesifen
Authors: Tkachenko I.V. , Antonenko A.M. , Bardov V.G. , Omelchuk S.T.
Published: April 2023

Chemical plant protection pro­ducts account for at least 3 % of all biosphere pollutants and are the most studied pollutants on our planet. A very significant potential risk to public health is the consumption of foodstuffs contaminated with residual quantities of pesticide compounds. The aim of the work was to assess the potential hazard to humans when eating apples and grapes treated with an insecticide based on spiromesifen. A stepwise study was used: the content of spiromesifen in apples and grapes was calculated; the risk to humans was assessed (comparing the values of the permissible daily intake of the compound with food products with the maximum possible daily intake); the integral hazard index of pesticide-contaminated products consumption was calculated and assessed. The results obtained for the determination of residual amounts of spiromesifen in apples and grapes made it possible to substantiate the value of its maximum allowable value – 0.02 mg/kg; apple and grape juices – 0.01 mg/kg. It was found that the actual intake of spiromesifen with apples and grapes can be 0.0065 mg, and this does not exceed 0.5% of the permissible daily intake, or 0.7% of the estimated permissible amount of spiromesifen that can be consumed with food. According to the value of the integral index of hazard in contaminated food consumption (6 points) spiromesifen belongs to class 3 – moderately dangerous to humans. It has been established that substantiated standards for spiromesifen make it possible to ensure the safety of consumption of grapes and apples grown with the Oberon Rapid 240 SC application, as well as the use of other pesticide formulations based on this substance on other crops.
Medico-social substantiation of the issue of quality of life in patients with breast cancer and finding ways to improve it
Authors: Zub V.О.
Published: April 2023

The quality of life of patients is one of the indicators of the medical care effectiveness for cancer patients. In order to study the main aspects of the quality of life of patients with breast cancer, a survey of 400 patients at the stage of their inpatient treatment in oncological institutions in nine regions of Ukraine (Chernihiv, Zaporizhia, Dnipropetrovsk, Kyiv, Poltava, Khmelnytsky, Ivano-Frankivsk, Zakarpattia and Lviv) using the EORTC QLQ-C30 and EORTC QLQ-BR45 questionnaires was carried out. In Ukraine, as of the pre-war period (November 2021 – February 2022), the quality of life of breast cancer patients equaled 53.22 on a 100-point scale. The most pronounced impact of breast cancer on the quality of life of the patient was observed in the psycho-emotional sphere (71.26), role functioning (70.48), views on future prospects (30.95). Patients complained of financial difficulties (44.19), fatigue (35.16), sleep disturbances (33.00), hair loss (43.41), as well as decreased sexual function (16.06) and pleasure (18.16 points). Given the low quality of life of breast cancer patients, they need psychological support, which should be aimed at adapting to the manifestations of the disease and future prospects, and the quality of life of patients should be one of the indicators in the course of treatment and providing psychological support. Since patients who have received social and psychological support from their doctors and friends/family have higher quality of life, we consider it necessary to focus on developing a comprehensive program to support breast cancer patients in collaboration with society, family and workplace.
Clinical case severe course of coronavirus infection (COVID-19) in a child
Authors: Mateiko H.B. , Matvisiv M.V. , Pylyuk I.I. , Nesterova T.V. , Glushko U.A.
Published: April 2023

A clinical case of a severe course of coronavirus infection (COVID-19) in an adolescent is described. A 15-year-old patient was admitted to the surgical department with suspicion of acute appendicitis. According to the results of the ultrasound examination of the abdomen it was decided to perform diagnostic laparoscopy, which excluded the presence of acute surgical pathology. The increase of intoxication symptoms and the data of epidemiological anamnesis, concerning the contact with patients with the catarrhal symptoms 3-4 weeks before the disease onset, were the reason for the examination for SARS-CoV-2. On the basis of a positive  polymerase chain reaction for SARS-CoV-2 and existing pneumonia according to X-ray examination of the chest, the patient was transferred to an infectious disease hospital. Further examination revealed polyserositis (ascites, pleurisy); acute kidney damage (high levels of urea, creatinine, oliguria); cytolytic syndrome (increased level of aspartate aminotransferase in 1,7 times); high level of C-reactive protein and increased level of procalcitonin, which corresponded to the local infection. After the administration of the first dose of intravenous immunoglobulin the patient's condition has improved significantly. The set of symptoms of multiple organ damage in this clinical case provides grounds for differential diagnosis between coronavirus disease and multisystem inflammatory syndrome in children on the background of the coronavirus infection COVID-19. Based on the diagnostic criteria for multisystem inflammatory syndrome in children presented by the World Health Organization, the Centers for Disease Control and Prevention, the British Medical Journal, the American Academy of Pediatrics, this clinical case can be considered as multisystem inflammatory syndrome.
Clinical case of a pelvic fracture with massive retroperitoneal hematoma
Authors: Krishtafor D.A. , Krishtafor A.A. , Tsarev A.V. , Balyk D.V. , Halushchak A.Y. , Pelekh V.A.
Published: April 2023

Pelvic fracture is a serious injury that carries a significant risk of mortality. The cause of death in these victims is the formation of a retroperitoneal hematoma and massive bleeding. The article presents a clinical case of a pelvic fracture with a massive retroperitoneal hematoma in a 30-year-old man who was brought to the regional hospital in hemorrhagic shock 5 hours after falling from the 5th floor. Upon admission, computed tomography (CT) showed a rupture of the pubic joint, a multifragmentary fracture of the sacrum, and the presence of a hematoma in the right parts of the pelvic cavity. Despite immobilization of the fracture and massive transfusion, it was not possible to stabilize the patient's hemodynamics and improve the parameters of the patient's general blood analysis. Due to the clinic of active bleeding, the patient repeatedly underwent control ultrasound examinations of the abdominal cavity and pleural sinuses, but the presence of free fluid in the abdominal cavity could be confirmed only after 12 hours of treatment. At the emergency laparotomy, a hematoma was found, which spread through the retroperitoneal space to the level of the diaphragmatic crura and the root of the small-bowel mesentery in a relatively thin layer, which explained the impossibility of its visualization by ultrasound or CT. Despite the intensive care measures, over the next few days the patient's condition gradually worsened, multiple organ failure developed. On the 3rd day after the operation, the patient died due to progressive multiple organ failure. The described case demonstrates the severity of the condition of victims with a traumatic retroperitoneal hematoma and the difficulty of diagnosis and effective treatment using conservative methods.
Якість інтегрованої звітності та її характеристики
Authors: Орлов Ігор Віталійович
Published: April 2023

У статті проведено дослідження якості інтегрованої звітності. Інтегрована звітність є формою корпоративної звітності, яка представляє інформацію щодо створення цінності для всіх стейкхолдерів, враховуючи фінансову, нефінансову, екологічну, соціальну та управлінську інформацію. Ця форма звіту дозволяє зрозуміти взаємозв’язки між фінансовими та нефінансовими факторами ефективності підприємства, які створюють додаткову цінність. Дослідження показують, що інтегрована звітність покращує інформаційне середовище компаній, підвищує їх ринкову оцінку та пом’якшує інформаційну асиметрію між внутрішніми та зовнішніми користувачами звітності. У 2013 році Міжнародна рада інтегрованої звітності була створена для визначення фундаментальних концепцій і принципів формування інтегрованого звіту, а також для оцінки його якості. Наразі близько 500 компаній по всьому світі публікують інтегрований звіт згідно з рекомендаціями Міжнародної ради інтегрованої звітності. Структура корпоративного управління та практики корпоративної організації допомагають утворювати цілісний погляд на розробку стратегії, що призводить до інтеграції різних аспектів створення вартості підприємства, а також до збільшення доданої вартості і представлення якісної інформації через інтегровану звітність. У статті наведено критерії оцінки якості інтегрованої звітності. Вказані критерії розглядаються Міжнародною радою інтегрованої звітності як обов’язкові вимоги. Розкриття якісної інформації через інтегровану звітність надає можливість об’єктивно оцінити результати та перспективи розвитку підприємства, вплив його діяльності на навколишнє середовище та суспільство.
Напрями цифровізації ресторанного бізнесу
Authors: Олійник Оксана Вікторівна , Шестакова Анна Валеріївна , Ярмолюк Діна Іванівна
Published: April 2023

У статті розкриваються ключові напрями цифровізації ресторанного бізнесу, якому також доводиться переводити свої бізнес-процеси в цифровий вимір для забезпечення стабільної діяльності в умовах карантинних обмежень та воєнного стану. Сьогодні цифрова трансформація господарської діяльності ресторанів є нормальним явищем, до якого схвально ставляться і клієнти закладів громадського харчування, оскільки разом з ним відчувають суттєве покращення сервісу. Автори аргументують, що світова пандемія COVID-19 насправді пришвидшила стрімкий розвиток електронної комерції для всіх видів економічної діяльності та сфер економіки, зокрема, спричинила зміну підходу до організації роботи ресторанної індустрії та змусила адміністрацію шукати нові напрями взаємодії з клієнтами та утримувати їх. Зараз можна сказати напевно, що цифрові рішення допомогли ресторанам суттєво розширити асортимент своїх послуг, а для клієнтів – отримати можливість безконтактної оплати по рахунку, мережу кіосків для безконтактного замовлення, замовлення онлайн через вебсайт і мобільний додаток, програму лояльності та ін. Відтак організація бізнесу з впровадженням клієнтоорієнтованих сервісів дала змогу суб’єктам ресторанного бізнесу утриматися на ринку послуг закладів харчування. За результатами проведеного дослідження обґрунтовується думка, що власникам ресторанного бізнесу варто зосередити свою увагу передусім на розвитку сервісу онлайн-доставки їжі. Цифровізація ресторанного бізнесу дозволяє клієнтам замовляти їжу онлайн і отримувати її до порога будинку чи навіть квартири. Натомість власники ресторанів можуть ефективно обробляти замовлення онлайн за допомогою онлайн-платформ доставки їжі. Зазначається, що серед ключових переваг цифровізації для розвитку ресторанного бізнесу ключове місце займає можливість використовувати інструменти медіамаркетингу. Цифровий маркетинг дозволяє ресторанам зв’язуватися з клієнтами за допомогою способів, які є неможливими за умов використання традиційних (консервативних) каналів комунікації: візуальних платформ Instagram, Pinterest і TikTok, взаємодії з лідерами думок (інфлюенсерами) та фуд-блогерами, активного ведення вебсайту ресторану та ін. У зв’язку з цим стверджується, що інтернет створив таке цифрове середовище, де суб’єкти ресторанного бізнесу можуть з легкістю створювати корисний контент і ділитися ним зі світом. І для маленьких кав’ярень, і для великих ресторанів це створює можливість знаходити своїх ідеальних клієнтів. За допомогою інструменту медіамаркетингу навіть підприємці з мінімальною цифровою грамотністю можуть максимально ефективно просувати свій бізнес в мережі «Інтернет», ефективно комунікувати з цільовою аудиторією, залишатися вірними своєму бренду.
Кадрова політика збереження інтелектуального капіталу: в очікуванні Індустрії 5.0
Authors: Зачосова Наталія Володимирівна , Кімлик Василь Миколайович , Замогильна Аліна Віталіївна
Published: April 2023

Метою дослідження стало обґрунтування та розробка теоретико-методичних положень кадрової політики підприємств, що буде адаптованою під реалії воєнного часу та придатною до використання в умовах поширення тенденції Індустрії 5.0. Визначено актуальні питання формування та реалізації інструментів кадрової політики суб’єктів господарювання у сучасних економічних умовах. Обґрунтовано, що Індустрія 5.0 диктує параметри людиноцентризму у бізнесі, тобто, основою кадрової політики має стати мотиваційний механізм, інструментарій розвитку потенціалу працівника, набуття ним нових професійних характеристик під впливом постійного і безперервного процесу навчання, схильність до якого стимулюється менеджментом компанії. Проаналізовано значення кадрової політики для збереження інтелектуального потенціалу підприємства та формування його кадрового капіталу. Досліджено сутність та основні цілі кадрової політики в умовах війни та в очікуванні Індустрії 5.0. Встановлено, що ефективність управління персоналом можна підвищити за рахунок удосконалення механізму формування кадрової політики підприємства та спрямування її на збереження і примноження інтелектуального потенціалу суб’єкта господарювання. Окреслено елементи механізму реалізації кадрової політики на вітчизняному підприємстві. Конкретизовано фактори впливу на кадрову політику вітчизняних підприємств в умовах війни і у мирний час.
Тенденції зростання у навколишньому середовищі мікропластику та його вплив на споживачів послуг індустрії гостинності
Authors: Чагайда Андрій Олегович , Тарасюк Галина Миколаївна
Published: April 2023

У статті проведено аналіз впливу мікропластику на навколишнє середовище. Особлива увага належить дослідженням, які пов’язані з використанням пластикових уапаковок у харчовій індрустрії та сфері гостинності. Щоб повністю оцінити вплив нашої глобальної залежності від пластику на здоров’я, слід не лише враховувати кожен етап його життєвого циклу, але й усі можливі шляхи впливу різноманітних речовин, що використовуються та виділяються впродовж цього життєвого циклу. Проведено дослідження ставлення молоді до проблеми забруднення навколишнього середовища, а саме проведено анкетування 174 респондентів віком від 18 до 23 років (43,2 % – чоловіки, 56,8 % – жінки). Більшість респондентів не усвідомлює реальну величину проблеми, адже мікропластикове сміття ще залишається поза увагою соціальної реклами, яка популяризує вирішення глобальної проблеми забруднення, не акцентуючи увагу на негативних впливах для здоров’я людини. Всупереч факту споживання людьми великої кількості мікропластику, наразі важко сказати, як він впливає на наш організм. Багато досліджень проведено на недостатньо якісному рівні, тому не надають достовірної інформації. Інші ж дані є несистематизованими та не дають побачити повну картину проблеми. Обґрунтовано, що одним із правильних шляхів зменшення негативного впливу на навколишнє середовище, на відміну від захоронення на спеціально відведених полігонах, є перероблення та повторне використання пластику. Така переробка полегшується при окремому збиранні відходів, що відбувається в Україні на данний час без відповідного законодавчого забезпечення та стимулюючих заходів.
Fintech as a concept of functional economic science
Authors: Petruk O.M. , Burtsev Ya.I. , Zaschipas S.M. , Popov O.H.
Published: April 2023

The article is devoted to the disclosure of the theoretical foundations of fintech as a concept of functional economic sciences (finance, accounting, economics). Nowadays, there are various approaches to the disclosure of this concept, which does not contribute to the development of an adequate economic policy of the state and legislative regulation in this area. Historical approach, content analysis, system and functional approaches were used to reveal the content of the definition. The analysis of existing approaches allowed us to conclude that there are four basic approaches to the interpretation of fintech: fintech as a technology, fintech as an innovation and a business model; fintech as an industry, fintech as a service. All of them have both weak and strong arguments in their favor, but none of them can exist without the latest technologies that form the basis of fintech. As a result of the study, it was proved that fintech is an innovative financial industry based on digital technologies, which lead to the intensification and growth of the efficiency of financial services. The statement about the emergence of a new fintech industry is grounded in the institutional part as a set of business entities that develop and implement modern innovative technologies in the financial sphere. Regarding traditional financial market intermediaries, it is worth talking about the transformation of their business models under the influence of modern innovative technologies. The latter happens without changing their functional role in the financial market.
Microbial diversity of bivalve shellfish and the use of innovative technologies for
preservation, monitoring and shelf-life extension
Authors: Odeyemi O.A. , Dabade D.S. , Amin M. , Dewi F.R. , Kasan N.A. , Onyeaka H. , Dada A.C. , D. Stratev , Anyogu A.
Published: April 2023

Bivalve molluscs, comprising oysters and mussels, are important seafood products as they
represent over 56% of marine and coastal production and account for 12% of the seafood
trade with a value of over USD 34 billion dollars. Bivalve molluscs are increasingly
popular among consumers because of their high nutritional value and are considered
sustainable seafood products as they do not require feed inputs and can make a significant
contribution to food security. As filter feeders, bivalve molluscs can accumulate
microorganisms, and improper post-harvesting handling and storage procedures could
support the growth of spoilage and pathogenic microorganisms, causing spoilage and
potential safety issues. At the same time, there is an increasing demand by consumers for
fresh and minimally processed foods. Therefore, understanding the microbial diversity of
bivalve molluscs and methods to control microbial growth is of increasing research
interest. This review highlighted the recent developments in the understanding of the
microbial community of bivalve molluscs and the use of innovative technologies for the
preservation and shelf-life extension of seafood.
One’s Loss is Another’s Gain? The Role of Message Framing, Information Type, and Political Ideology in Political Advertising
Authors:   , Grimwade Lachlan
Published: April 2023

Many political advertisements emphasise the benefits on offer if you vote, or the possible consequences if you don’t. The abstractness (i.e., presentation in a vague way) and concreteness (i.e., presentation in a specific way) also varies across political advertisements. To date, minimal research has examined the effectiveness of gain versus loss framed messages and abstract versus concrete appeals in political advertising. Moreover, little is known about how these effects differ between liberal (i.e., left-wing) and conservative (i.e., right-wing) political ideologies.

Building upon message framing and construal level theory, this paper examines the interplay of message framing (gain versus loss) and information type (abstract versus concrete) on attitude towards the ad, message persuasiveness, and ad-brand congruence. It also investigates the moderating role of political ideology (liberal versus conservative) on these main effects. A 2 (message framing: gain versus loss) × 2 (information type: abstract versus concrete) between-subjects experiment (n = 809) was conducted, in which individual differences in political ideology were measured.

Findings from this research offer valuable contributions through the extension of message framing and construal level theory to the nascent but influential field of political advertising. Contrary to expectations, the results revealed that gain (versus loss) framed advertisements are more effective in political advertising. Concrete (versus abstract) appeals also resulted in more positive attitudes towards the ad and greater message persuasiveness, but no difference in ad-brand congruence. This indicated that concrete appeals were more effective, but not perceived to be better suited to participants’ preferred political party. Additionally, political ideology moderated the effects of message framing. That is, despite gain frames being more effective overall, loss frames were more effective among conservatives than liberals.

These findings contribute to message framing research and construal level theory. Findings also provide practical implications; gain (versus loss) frames and concrete (versus abstract) appeals are independently more effective in political advertising. However, if an advertiser were to use a loss frame, it would be better received among conservatives rather than among liberals.
МЕТОДОЛОГИЧЕСКИЕ ПОДХОДЫ К ИЗУЧЕНИЮ ПРОЦЕССОВ ТРАНСФОРМАЦИИ ГЕНДЕРНОГО ПОВЕДЕНИЯ В АСПЕКТЕ ИЗМЕНЕНИЯ ИНСТИТУЦИОНАЛЬНЫХ УСЛОВИЙ И ГЕНЕЗИСА ОБЩЕСТВЕННОГО РАЗВИТИЯ
Authors: Абдулаева Заира Запировна
Published: April 2023

В данной статье на основе анализа и систематизации методологических подходов и теоретических положений, раскрывающих сущность гендерного поведения, определены особенности его формирования и трансформации в современных реалиях изменения институциональных условий и генезиса общественного развития. Уточнено понятие «гендерное поведение» в ракурсе, позволяющем исследовать его как в социально-психологической, так и в социокультурной проекциях. Обосновано, что, несмотря на ряд отечественных исследований, проведенных в последние годы, вопросы формирования гендерного поведения на основе изучения культурных, этнических, религиозных, региональных особенностей населения пока не нашли должного внимания среди российских исследователей. В ходе исследования активно использовались общенаучные методы сравнения, аналогии, сравнительного анализа, систематизации, применялся гендерный подход к анализу экономических, социальных и политических явлений.
МОДЕРНИЗАЦИЯ РОССИИ В УСЛОВИЯХ инновационных преобразований
Authors: Иванова Наталия Александровна
Published: April 2023

Актуальность предложенной статьи обусловлена развитием инновационной экономики региона за счет инновационной модернизации на основе рационального использования экономического, интеллектуального и социального потенциалов. Акцент делается на возрастание роли науки и инноваций, повышение качества человеческого капитала, усиление значимости социальных факторов в региональной политике. Комплексное изучение экономических, социальных и институциональных вопросов, связанных с разработкой новой модели инновационной модернизации региональной экономики в соответствии с инновационными преобразованиями отражает актуальность данного исследования.
ИСПОЛЬЗОВАНИЕ ИНФОРМАЦИОННЫХ ТЕХНОЛОГИЙ ДЛЯ ПОВЫШЕНИЯ ЭФФЕКТИВНОСТИ ФУНКЦИОНИРОВАНИЯ ПРОДУКТОВЫХ ПОДКОМПЛЕКСОВ АПК СКФО В УСЛОВИЯХ СОВРЕМЕННЫХ ВЫЗОВОВ
Authors: Балиянц Карина Михаиловна
Published: April 2023

В данной статье рассматриваются основные факторы, влияющие на устойчивое функционирование экономики продуктовых подкомплексов региона на основе использования информационно-коммуникационных технологий и цифровизации отраслей АПК в условиях влияния различных внешних воздействий. В ходе подготовки были использованы такие научные методы исследования, как эмпирический, статистический анализ, метод, научные и аналитические исследования отечественных ученых и специалистов по изучаемым вопросам. В результате проведенного исследования были сделаны выводы/получены результаты, свидетельствующие об определенной взаимосвязи развития экономики продовольственных подкомплексов АПК региона с расширением внедрения и использования инновационных цифровых и информационно-коммуникационных технологий. Полученные в ходе анализа данные позволяют сделать вывод, что современные вызовы в экономике продуктовых подкомплексов АПК можно рассматривать как задачи, формирующиеся под воздействием внутренних и внешних условий и требующих решения с помощью цифровой трансформации с учетом социальных и экологических аспектов, а также выдвинуть ряд предложений для формирования социально-экономических предпосылок широкого внедрения цифровых технологий в регионе, заключающихся в государственном координировании управленческих действий по созданию и совершенствованию инфраструктуры сельских территорий, обучении кадров высшего и среднего звена в сельской местности, создании выгодной экономической среды эффективной производственной деятельности хозяйств, разработке стандартов последовательной автоматизации для достижения предприятиями АПК уровня точного цифрового производства.
РАЗВИТИЕ РОСАГРОЛИЗИНГА КАК ИНСТИТУТА ТЕХНИЧЕСКОЙ И ТЕХНОЛОГИЧЕСКОЙ МОДЕРНИЗАЦИИ ОТЕЧЕСТВЕННОГО АПК
Authors: Клейменова Юлия Александровна , Баяндурян Галина Левоновна
Published: April 2023

В статье рассматриваются этапы развития лизинга сельскохозяйственной техники. Авторы провели сравнительную характеристику условий лизинга ОАО «Росагроснаб» и ОАО «Росагролизинг», что позволило выявить положительные и отрицательные направления в развитии агролизинга Особое внимание уделяется характеристике развития АО «Росагролизинга» как института технической и технологической модернизации отечественного АПК. В процессе исследования было выявлено, что компания большее внимание уделяет работе с сельхозтоваропроизводителями. Компания постоянно совершенствует условия лизинга, подстраивая их под меняющиеся условия потребительского спроса. С производителями сельскохозяйственной техники Росагролизинг взаимодействует в меньшей степени, либо их интересы не учитываются вообще, либо учитываются частично в отношении крупнейших производителей. Теоретическую базу по вопросам развития лизинга в аграрном секторе экономики сформировали труды отечественных и зарубежных исследователей. В результате проведенного исследования был сделан вывод о необходимости дальнейшей трансформации деятельности АО «Росагролизинг», разработке и применении эффективных инструментов государственной регулятивной политики, направленных на развитие как сельскохозяйственных товаропроизводителей, так и производителей сельскохозяйственной техники.