bluuebunny/crossref_metadata_2025 huggingface dataset:
Physical Examination Attitudes and Practices Scale: Psychometric Evaluation on Turkish Nurses
Authors: Koc Serife , Eren Handan , Celik Demet
Published: March 2024

Background and Purpose:Physical examination (PE) is an important element used in the diagnostic process. This cross-sectional and methodological study was conducted methodologically to test cross-cultural and linguistic adaptation of the Turkish version of the Physical Examination Attitudes and Practices Scale and to test the reliability and validity of Turkish nurses.Methods:The study was carried out with a methodological cross-sectional design, with 372 nurses working in different departments at a state hospital.Results:The content validity index was found to be 0.87. Item-total score correlation coefficients were above .30; Cronbach’s coefficient α (alpha) was found to be .89.Conclusions:The instrument is an acceptable, valid, and reliable tool in Turkish for evaluating the attitudes and practices toward PE. Attitudes toward PE can be examined by health professionals working in different fields and cultures.
Beyond Men’s Experiences: Scale Development and Psychometric Testing of the Fitness in Nursing Scale—Men (FiNS-M©)
Authors: Smith Christopher M. , Horne Carolyn E. , Bowler Mark C.
Published: March 2024

Background and Purpose:Men believe they are perceived as unfit for nursing. No scales exist to measure perceptions of men’s fitness for nursing. Additionally, women have been largely excluded from this area of inquiry. This study’s purpose was to develop and test the psychometric properties of the Fitness in Nursing Scale for Men.Methods:Six hundred thirty-five nurses participated. Scale development entailed concept clarification, item development, and scale testing.Results:Confirmatory factor analysis suggested a two-factor structure (F1: nursing fitness and F2: strengths of men in nursing) which demonstrated good model fit, root mean square error of approximation = 0.059, 90% CI (0.056, 0.063), standardized root mean square residual = 0.055, comparative fit index = 0.932, Tucker–Lewis index = 0.927, and ωt= 0.98. Invariance held. Latent means were not significantly different for women (M= 5.90) compared with men (M= 5.92).Conclusions:Findings suggest men are perceived as fit for nursing, but results are inconsistent with men’s qualitative experiences. Future research should attempt to reconcile the disagreement. Findings can inform cultural awareness strategies in the workplace and classroom.
Farsi Version of the Body Image Concern Inventory in Iranian Hemodialysis Patients: Validity and Reliability
Authors: Sharif-Nia Hamid , Froelicher Erika Sivarajan , Bagheri-Nesami Masoumeh , Mosazadeh Hasan , Jafari-Koulaee Azar , Goudarzian Amir Hossein
Published: March 2024

Background and Purpose:Patients on hemodialysis often struggle with their body image. This study was conducted with the aim of investigating the validity and reliability of the Persian version of the body image concern questionnaire for the first time in hemodialysis patients in Iran.Methods:In this cross-sectional study, 400 hemodialysis patients from Iran were assessed using the Body Image Concern Inventory (BICI). By using exploratory factor analysis (EFA; with Maximum Likelihood factor analysis and Promax rotation) and confirmatory factor analysis, the construct validity of BICI was assessed. To check for internal consistency, the average interitem correlation, Cronbach’s coefficient α (alpha), and McDonald’s omega coefficients were used. Stability was assessed with intraclass correlation coefficient (ICC).Results:The participants’ average age was 53.2 (SD= 13.2) years, and more than half of them were women (54.60%). Four factors extracted from EFA show that the total cumulative variance explained by these factors was 44.46% of the total variance. Item factor loadings varied between .415 and 0.970. Internal consistency coefficients were considered acceptable (>0.7). Also, stability was evaluated as good (ICC = 0.839).Conclusions:The Farsi version of the BICI scale as a self‐report measure of concerns about dysmorphic appearance has 19 items and shows acceptable reliability and validity. Consequently, the scale can be used by nurses to evaluate body image among Farsi-speaking hemodialysis patients, which can help them take necessary actions to decrease the level of concerns in these patients.
Migration-Related Stress Among Haitians: Cross-Cultural Translation of the Demands of Immigration Scale
Authors: Fanfan Dany
Published: March 2024

Background and Purpose:Although the Haitian population in the United States continues to grow, there is a lack of instruments in Haitian Creole to assess risk factors associated with poor mental health such as migration-related stress. This study described the translation of the Demands of Immigration Scale (DIS) and evaluated psychometric properties, meaning equivalence, and understandability of the Haitian Creole/English DIS.Methods:I applied the Functional Assessment of Chronic Illness Therapy translation procedures and recruited 76 first-generation Haitian immigrants to pilot test the DIS.Results:Reliability was strong (α > .93). Meaning equivalence was maintained (r= .979), 75% understood both DIS versions equally, and 80% rated the translation as excellent/good. The DIS significantly correlated with gender, income, age, age at migration, English fluency, and depression.Conclusions:The DIS can reliably identify immigration-related social determinants of mental health and is ready for use in Haitian Creole.
Validity and Reliability of the Persian Version of Positive Body Image Among Adolescents Scale
Authors: Sharif Nia Hamid , Sivarajan Froelicher Erika , Mosazadeh Hasan , Rezazadeh Fazeli Azadeh , Goudarzian Amir Hossein , Toloei Maryam , Ebrahimi Faezeh
Published: March 2024

Background and Purpose:This study evaluated the validity and reliability of the Persian version of Positive Body Image among Adolescents Scale (PBIAS-P) in Tehran, Iran, in order to better understand adolescents’ positive perceptions of their physical selves and the accompanying thoughts and emotions.Methods:This cross-sectional study was carried out involving adolescents from Tehran Province, Iran, in 2022. Both exploratory factor analysis and confirmatory factor analysis were performed in order to evaluate the construct validity of the PBIAS-P. Cronbach’s alpha, McDonald’s omega, and intraclass correlation coefficients were also used to confirm the internal consistency of the scale.Results:The findings indicate that three factors extracted from the PBIAS-P account for 50.1% of the total variance. The model fit is considered good based on cut points for various fit indices. All factors had values of Cronbach’s alpha, McDonald’s omega, and average interitem correlation above .73, .74 and .4, respectively. Also, test–retest reliability for three factors was acceptable.Conclusions:The PBIAS-P has acceptable validity and reliability in Iranian adolescents, making it useful for researchers, psychologists, and health care professionals.
Chronic Disease Multimorbidity Among Transgender People Living With HIV in North America
Authors: Rich Ashleigh J. , Poteat Tonia , Koehoorn Mieke , Althoff Keri N. , Lesko Catherine , Silverberg Michael J. , Moore Richard , Horberg Michael , Thorne Jennifer , Gebo Kelly , Coburn Sally , Loutfy Mona , Rebeiro Peter F. , Napravnik Sonia , McGinnis Kathleen , Nijhawan Ank E. , Lang Raynell , Ding Erin , Hogg Robert S. ,   for the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the International epidemiology Databases to Evaluate AIDS (IeDEA)
Published: March 2024

Despite the growing importance of HIV clinical care and research, scarce research has investigated multimorbidity among transgender populations. This study investigated multimorbidity burden for transgender people living with HIV (PLWH) using data from a large longitudinal cohort collaboration representative of HIV care-engaged adults in North America with cisgender (cis) comparators. Multivariable Poisson regression estimated chronic disease multimorbidity (HIV and ≥1 of chronic kidney disease, liver fibrosis, type two diabetes mellitus, hypertension, hyperlipidemia, and anxiety/depression) prevalence and incidence rate ratios by gender identity from January 2000 through December 2016 among adults (≥18 years old) engaged in HIV care in the United States and Canada among the North American TRAnsgender Cohort Collaboration, nested within the North American AIDS Cohort Collaboration on Research and Design. The total study sample included 301 transgender women (TW), 26 transgender men (TM), 11,504 cis women (CW), and 51,029 cis men (CM). At study entry, TW and TM were younger and more TW and TM were Black compared with CM. The prevalence and incidence of chronic disease multimorbidity were elevated for transgender PLWH, though without consistent statistically significant effects. Suggestive evidence of elevated multimorbidity and potential disparity among TW and TM compared with CW and CM in the current study highlights the importance of future studies with improved gender ascertainment and the ability to recruit larger transgender samples. Attention to intervenable chronic disease risk factors including smoking, and potentially unique vulnerabilities for TW vs TM, is also warranted.
The Effect Dose and Soaking Time of Camellia sinensis Solution to the Egg Adhesion and Hatching of Pangasionodon hypophthalmus
Authors: Baihaki Aldi , Nur Asiah  , Nuraini Nuraini
Published: March 2024

Cultivation of Pangasianodon hypophthalmus is growing rapidly, but there was a problem with the egg’s adhesiveness. Overcome this problem given a tea solution that serves as a remove of Pangasianodon hypophthalmus egg adhesion. This study conducted on June 2022 at Fish Hatchery and Breeding Laboratory, Faculty of Fisheries and Marine, University of Riau. The purpose of this study was determining the effect of immersion eggs with different doses and immersion duration of the black tea (Camellia sinensis) solution on adhesion of Pangasianodon hypophthalmus eggs. This study used a Completely Randomized Design Factorial with 2 factors. The first factor was the dose (g/L) of the black tea with 4 levels; 0 (D0), 8 (D8), 10 (D10), and 12 (D12). The second factor was the immersion duration (minutes) with three levels of 3 (W3), 4 (W4), and 5 (W5). Pangasianodon hypophthalmus larvae reared for 7 days. Parameters measured were egg adhesion, fertilization rate, hatching rate, survival rate, and water quality. The result showed that the doses of C. sinensis solution had a significant effect (P<0.05) on the degree of fertilization and hatching of Pangasianodon hypophthalmus eggs.  The  optimum  treatment  with  a  dose  of  10  g/L  and  4  minutes  (D10W4)  give  increased  eggs adhesion 5.99%, fertilization rate 94.13%, hatching rate 92.88%, and survival rate 96.99%. The water quality during the study were temperature 26.7-27.9OC, pH of larvae maintenance water 6.5-7.1 and DO 4.0-5.2 mg/L.  There is an interaction between dose and immersion duration of C. sinensis solution to the egg adhesion and hatching eggs of Pangasianodon hypophthalmus.
PRINCIPLES OF ANTONYMOUS LEXEMIC COMBINATION IN INDONESIAN
Authors: Putu Wijana I Dewa
Published: March 2024

This article deals with Indonesian lexemic combination whose elements consisting of lexemes having antonymous meaning. By using data collected introspectively whose grammaticality and acceptability are tested with other Indonesian native speakers, it is found that the combinations are governed by three main principles, i.e. formal, semantic, and stylistic principles. The formal principle can further be classified into rhyming, phonological, and length principle. While, the semantic principle can be differentiated into marked, diametric and chronological, equity, idiomatic, and gender principle. Those principles seems to be hierarchical whose dominance has not been revealed in this research. Therefore, the more serious research concerning this matter is urgently needed.
UNSUR DRAMATIK PADA FILM ALI & RATU RATU QUEENS DALAM MEMBANGUN PESAN KEKELUARGAAN
Authors: Adriyani Asti Widya , Suharijadi Didik , Astuti Soekma Yeni , Zamroni Muhammad , Hartanto Denny Antyo
Published: March 2024

The film "Ali & the Queens" is an example of a family-themed movie. This film has an intriguing storyline as it utilizes dramatic elements to emphasize the message of family bonds. The relationship between Ali and the Queens is predominantly focused on conveying the message of kinship. Ali and the Queens are a family without any blood ties. Their relationship initially starts from a mutually beneficial arrangement. Moreover, their familiarity grows as they are fellow immigrants from the same country. The sense of family between Ali and the Queens develops while living in the same apartment, fostering closeness and care for each other. The purpose of this study is to explore how the dramatic elements in the film "Ali & the Queens" contribute to conveying the message of family. This research employs a qualitative descriptive method. Data collection techniques involve observation, documentation, and literature review. The results of the study indicate that there are ten scenes supported by dramatic elements in conveying the message of family. Three scenes are supported by conflict, three scenes by suspense, two scenes by curiosity, and two scenes by surprise.
MAKNA KONTEKSTUAL “SAMARINDA BEBAS TAMBANG” PADA BERITA DARING: KAJIAN EKOLINGUISTIK
Authors: Wenerlee Valend Young , Kristina Milla , Wahyuni Ian
Published: March 2024

The purpose of this research is to describe the contextual meaning of some online news on kaltimpost.id and Pojoksatu.id regarding "Samarinda Free of Mining". This research method uses qualitative method and descriptive approach. This type of research is literature, which is research whose data is taken mainly from literature (books, documents, articles, reports, newspapers, and so on). The data in this research are words, phrases, and sentences in online news that discuss "Samarinda Free of Mining". The source of data in this research is online news kaltimpost.id uploaded on April 5, 2023, Pojoksatu.id uploaded on April 3, 2023, and online news mediakaltim.com uploaded on March 20, 2023. The results of research on online news kaltimpost.id, Pojoksatu.id, and mediakaltim.com show that contextual meaning refers to natural damage and disruption of animal ecosystems in the sea and on land due to mining activities.
KONSTRUKSI FRASA ADJEKTIVAL DALAM MAJALAH TEMPO 2022: “DARI UTARA MEMBELA KAUM HAWA”
Authors: Azizah Yulfiha Nur , Haryadi Haryadi
Published: March 2024

The purpose of this research is to (1) describe the types of adjective phrases, (2) describe the categories of attribute filling words in adjectival phrases, and (3) describe the syntactic function of adjektival phrases in the Special Report of Tempo Magazine, Sunday, December 25, 2022, entitled “Dari Utara Membela Kaum Hawa”. The research approach used is a qualitative descriptive and syntactic approach. The method of collecting data is through the listening method with advanced techniques, free engagement-free viewing, and note-taking techniques. Meanwhile, the data analysis method used is the Direct Element Division method with advanced techniques in the form of dissipation techniques, expansion techniques, and reverse techniques. The results of data analysis are presented through an informal presentation method. The results showed that 35 data of adjective phrases were divided into 17 endocentric adjective phrases and 18 exocentric adjective phrases. The types of adjective phrases found based on the number of cores consist of (1) attributive endocentric adjective phrases and (2) coordinative endocentric adjective phrases. The categories of filler words in adjective phrases are divided into (1) verbs, (2) adverbs, (3) nouns, and (4) pronouns. The adjective phrases found occupy several syntactic functions, namely (1) subject, (2) predicate, (3) object, (4) complement, and (5) adverb.
KAJIAN SEMIOTIKA CERPEN “MALAM MASIH PANJANG, DAN KALIAN AKAN MERASA LAPAR” KARYA MASDHAR ZAINAL
Authors: Pungky Ameylia Vanissa , Suryaman Maman
Published: March 2024

Artikel ini bertujuan mendiskusikan makna di balik tanda yang ada dalam karya sastra. Metode penelitian yang digunakan adalah metode kualitatif dengan analisis deskriptif. Objek material berupa cerpen “Malam Masih Panjang, dan Kalian akan Merasa Lapar” karya Masdhar Zainal, sedangkan objek formal berupa teori semiotika Charles Sanders Peirce, khususnya tentang ikon, indeks, dan simbol. Hasil penelitian menunjukkan adanya ikon malam, makanan, dan induk burung, indeks berupa potongan kisah yang dialami tokoh cerita (ayah, ibu, dan empat orang anak), dan simbol warung serta simbol peternak bebek. Rangkaian tanda-tanda berupa ikon, indeks, dan simbol tersebut dapat ditafsirkan sebagai ungkapan keprihatinan pengarang terhadap fenomena kemiskinan dalam masyarakat. Keutuhan cerita berdasarkan tanda semiotis berupa teks dan konteks, dapat dimaknai sebagai pesan yang ingin disampaikan oleh pengarang, yakni masih adanya kemiskinan yang perlu diatasi oleh berbagai pihak terkait, terutama oleh negara.
REPRESENTASI GIRL POWER PADA LAGU “TALLY” OLEH BLACKPINK
Authors: Fatonah Astri Amaliah , Handayani Wiwik Retno
Published: March 2024

A patriarchal culture dominated the representation of social reality, resulting in women's victimization. However, now the media is highlighting women in terms of educational achievements, so the existence of independent women is increasing. This research aims to discuss the representation of Girl Power shown in the video clip and lyrics of the song "Tally" by Blackpink. The research is based on qualitative methods with John Fiske's theoretical concepts of semiotics and Sara Mills' critical discourse analysis. The study results show that the video clip and lyrics of the song "Tally" by Blackpink represent Girl Power. The women depicted by Blackpink are strong. The ideology displayed stands out and is by the spirit of postfeminism that women's bodies cannot be used as objects and cannot be owned by men. Women's bodies and feelings can only be controlled by women without men's interference.
AN ANALYSIS DEIXIS OF PRESIDENT BARACK OBAMA’S FAREWELL ADDRESS IN NBC NEWS
Authors: Nouval Moh. Javier Arifian , Utama Insan Aji , Abdillah Muhammad Ilham , Mahendra Dzulfiqar Faisa , Salsabila Salma , Laila Malikstul
Published: March 2024

This research discusses the deixis that appeared in President Barack Obama's farewell speech on NBC News on January 10, 2017 in Chicago. The Farewell Address focused on key themes such as democracy, unity, and the importance of civic engagement. The speech reflects his enduring belief in the fundamental values that define the United States and his hope for a better future for all Americans. To achieve the purpose of Obama's speech, the researcher used a deixis approach. The method used in this study is a qualitative descriptive method by recording all the data that appears in President Barack Obama’s Farewell Address in NBC News. Deixis can be used to influence audiences or readers in a variety of ways, including in order to establish identity, build emotional connections, or influence views and attitudes. The results of the study show that Obama often uses the word "we" because Obama wants his audience to receive information and influence Americans with his words. The most dominant spatial data that appears is America.
NOVEL SUSU DAN TELUR KARYA MIEKO KAWAKAMI TERJEMAHAN ASRI PRATIWI WULANDARI: KAJIAN FEMINISME RADIKAL
Authors: Arlilianda Wahyu Gaesesita , Maslikatin Titik , Umniyyah Zahratul , Angelina Dewi , Muhamad Abu Bakar Ramadhan
Published: March 2024

The topic of feminism in Japan is something that society has not yet fully accepted. This is the reason why researchers chose the novel Susu and Eggs to be used as the object of study. The discrimination that occurs against female characters in the novel leads to extreme actions and thoughts regarding women's freedom regarding their rights. Therefore, the novel Susu and Eggs is studied using radical feminism theory. The aim of this research is to describe the structural analysis and aspects of radical feminism in the object of study. Data discovery was carried out using the library study method, namely reading the novel in its entirety. The description of the data is carried out through qualitative descriptive methods. The research results show that there is a relationship between the title, theme and characterization in the novel. The title relates to the major theme which is supported by the minor theme. The theme is depicted through events that support the characters' characters. On the other hand, the aspects of radical feminism found are divided into five parts, namely: (1) women and their bodies which are related to Midoriko and Natsuko. Midoriko as a teenager who hates the nature of women, then Natsuko as a single woman who cannot find pleasure in sex, but wants to have children through a sperm donor; (2) the inequality of roles in the household which is depicted through the character Yusa Rika who hates her ex-husband; (3) women's beauty standards which include women's body shape and nipple color; (4) stereotypes about women's bodies that discuss women's instincts to get pregnant and societal stigma that prioritizes the penis over the vagina; (5) and sexual violence which includes the act of rape against the character Zen Yuriko.
Refleksi Pengalaman Transendental dalam Seni Kontemporer
Authors: Nisa Nurul Komala Khoirun , Tridjata Caecilia , Murwanti Aprina
Published: March 2024

Transendental merupakan hal hal yang sukar dipahami, bersifat gaib dan abstrak. Pengalaman transendental tidak semua dapat merasakan dan mengalami kejadian dengan makhluk astral. Ketakutan atas pengalaman transendental merupakan hal yang dialami oleh pengalaman pribadi. Pengalaman yang dialami merupakan melihat, diganggu oleh makhluk astral. Karya tugas akhir yang berjudul Selamat Jalan, ini menerapkan metode pendekatan narasi simbolik dalam menyajikan perspektif baru terkait pengalaman transendental dengan membuat proses kreatif melalui membuat jurnal cerita mengenai pengalaman pengalaman yang telah dialami. Dengan pendekatan seni kontemporer diimplementasikan pada karya instalasi yang menghadirkan objek estetik dengan karya lukis arang. Karya ini sebuah refleksi bagi perupa dengan mensublimasikan melalui karya seni rupa atas ketakutan terhadap pengalaman transendental. Karya yang dibuat ini juga merupakan bentuk keberanian dalam ketakutan terhadap komentar orang lain yang tidak percaya akan hal gaib atau mahkluk astral . Sublimasi karya ini dituangkan ke dalam karya seni instalasi.
Konsep Visual Sign System Outdoor Bertema Ornamen Betawi Di Kampus A Universitas Negeri Jakarta
Authors: Nalendra Yudanio Yaka , Kherid Zaitun Y.A , Moerdisuroso Indro
Published: March 2024

Kebutuhan sign system luar-ruang di Universitas Negeri Jakarta sangat diperlukan terlebih untuk tamu yang baru pertama kali datang. Dikarenakan desain signage kurang menarik, penempatan kurang optimal, seperti terlalu tinggi dan tidak eye level. Maka dari itu, perupa mengambil Skripsi Penciptaan Karya Seni Rupa dengan judul “Desain Sign system Luar-Ruang Bertema Ornamen Tradisional Betawi Di Universitas Negeri Jakarta”. Bertujuan untuk memperbaharui sign system yang sudah ada di Universitas Negeri Jakarta dengan mengangkat ornamen tradisional Betawi sebagai identitas, berdasarkan lokasi. Penelitian ini menggunakan metode penelitian kualitatif. Teknik pengumpulan data yaitu dengan survey lapangan, kuesioner dan eksplorasi yang dianalisis menggunakan teknik analisis etnografis. Hasil dari penelitian berdasarkan analisis karya, desain sign system dirancang mampu mempermudah pengunjung dan sivitas akademika Universitas Negeri Jakarta untuk mengetahui lokasi-lokasi yang ada di dalam lingkungan kampus. Dengan desain sign system yang mengangkat tema kebudayaan lokal di tempat Universitas Negeri Jakarta berada, yaitu Kembang Kelapa. Terinspirasi dari ombak yang berada di Pantai Sunda Kelapa. Merupakan salah satu ikon budaya Betawi berdasarkan Peraturan Gubernur Provinsi DKI Jakarta Nomor 11 Tahun 2017, ayat 2. Ikon Kembang Kelapa dideformasi bentuk aslinya tanpa menghilangkan makna yang terkandung di dalamnya menjadi ornamen.
Kreasi Serat Jute Pada Bingkai Cermin Hias Berkonsepkan Eco Friendly Craft
Authors: Farida Siti , Mudjiati
Published: March 2024

Serat alam merupakan komoditas yang sangat prospektif dikembangkan. Salah satunya serat jute (Corchorus capsularis), serat alam yang berasal dari tanaman jute yang berasal dari bagian batang tanaman. Pohon jute merupakan tanaman tahunan yang tumbuh baik di tanah alluvial, yaitu tanah kering sedikit berpasir pada iklim tropis yang lembab, salah satunya Indonesia. Kebanyakan pemanfaatan serat jute di Indonesia hanya sebatas sebagai bahan  dasar pembuatan  karung  dan  pelapis  permadani. Penelitian ini dilakukan dengan tujuan insight penciptaan kreatif yang berpotensi dikembangkan serta memanfaatkan serat jute sebagai material utama dalam penciptaan karya seni rupa berupa produk cermin hias dengan mengambil struktur motif dan adaptasih teknik makramé. Metode penelitian dengan konsep pratice-based research sebagai penelitian yang dimulai dari  riset terkait studi pendahuluan objek dan  melakukan  praktik, mencatat dan mengumpulkan data-data yang dianggap penting dalam proses penciptaan. Melalui eksplorasi, riset dan praktik, serat jute dapat menghasilkan produk berupa cermin hias dengan pengaplikasian teknik makrame dan memanfaatkan zat pewarna alam.
Распространение вариантов вируса SARS-COV-2, вызывающих интерес (VOI) и находящихся под наблюдением (VUM), на основе количества их геномов, депонированных в базу данных GISAID за неделю с 16 по 22 марта 2024 г.
Authors: Дмитриева Людмила , Чумачкова Елена , Гусева Наталья , Осина Наталья , Зимирова Анастасия , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Щербакова Светлана , Кутырев Владимир
Published: March 2024

В обзоре представлена информация по циркулирующим в настоящее время вариантам вируса SARS-COV-2 Omicron вызывающих интерес (VOI) и находящихся под наблюдением (VUM), геномные последовательности которых размещены в международной базе данных GISAID за неделю с 16 по 22 марта 2024 г.
Graft Resorption After Posterior Distal Tibial Allograft Augmentation for Posterior Shoulder Instability
Authors: Luzzi Andrew , Boddapati Venkat , Rogalski Brandon L. , Knudsen Michael L. , Levine William N. , Jobin Charles M.
Published: March 2024

Case:

A 19-year-old man underwent arthroscopic posterior glenoid reconstruction with a distal tibia allograft (DTA) after failing 2 posterior, soft-tissue instability surgeries. Although he experienced near-complete resolution of symptoms and return to sport, graft resorption was noted 7 months postoperatively. The patient underwent revision surgery for screw removal.

Conclusion:

Graft resorption has not previously been reported in the setting of arthroscopic DTA use for posterior instability. It is believed that stress shielding contributed to resorption. In such situations, screw removal may be warranted. Consideration of alternative fixation techniques and additional investigation into the causes, clinical significance, and optimal management of posterior DTA resorption are warranted.
The effect of virtual reality in dentistry: A protocol for a systematic review and meta-analysis
Authors: Motahari-Nezhad Hossein , Sadeghdaghighi Aslan , Ashourioun Amir-Hossein
Published: March 2024

This systematic review and meta-analysis protocol outlines an investigation into the effects of Virtual Reality (VR) in dentistry. As a growing technological tool, VR offers immersive environments for patient education, anxiety and pain management, and professional skill enhancement in dental practice. Despite its growing use, empirical evidence on VR's efficacy remains fragmented and inconclusive. This review aims to consolidate current research, providing a comprehensive assessment of VR's impact across all health outcomes in dental care.
Adhering to the PRISMA-P guidelines, the study will include English-language, two-arm randomized controlled trials, comparing VR interventions with non-VR controls. The review will consider all dental patients, regardless of demographics, and will encompass various dental treatment settings. A search strategy employing two databases including PubMed and the Cochrane Library will identify relevant studies, followed by a systematic screening and data extraction process conducted by independent reviewers. The review will conduct a risk of bias assessment and employ a random effects meta-analysis for evidence synthesis. A subgroup analysis and meta-regression will explore factors affecting VR's effectiveness. Publication bias will be assessed using Trim and Fill, Begg and Egger methods, and the GRADE tool will evaluate the quality of evidence.
The review anticipates offering insights into the role of VR in enhancing patient-centered care. By synthesizing scattered evidence, it aims to identify specific health outcomes significantly impacted by VR applications. The findings are expected to guide future research and clinical practices, enhancing patient care in dentistry.
Fusion of Probabilistic Projections of Sea-Level Rise
Authors: Grandey Benjamin S. , Dauwels Justin , Koh Zhi Yang , Horton Benjamin P. , Chew Lock Yue
Published: March 2024

Alternative projections of sea-level rise from ice sheet mass loss differ markedly. The differences drive ambiguity in probabilistic projections of sea level. Can the alternative projections be combined to produce a single probabilistic projection that quantifies a best estimate of the scientific uncertainty? To produce this best estimate, we propose a fusion of alternative projections. The fusion combines the complementary strengths of the ‘medium confidence’ and the ‘low confidence’ projections. Two assumptions undergird the fusion. First, we assume that the ‘medium confidence’ projections reliably sample the most-likely central possibilities. Second, we assume that the p-box outer bound – which includes the ‘low confidence’ projections – provides a more reliable estimate of unlikely tail possibilities driven by poorly-understood processes. Accordingly, the fusion is weighted towards the ‘medium confidence’ projections near the median and towards the p-box outer bound near the tails. We demonstrate our proposed fusion by combining alternative projections of sea-level change at the end of the 21st century. The fusion provides probabilistic answers: according to the fusion, the probability of global mean sea-level change exceeding 1.0 m by 2100 is 6% under a low-emissions scenario and 31% under a high-emissions scenario. The fusion also informs summary statements based on credible intervals: under a high-emissions scenario, for example, we are 90% certain that global mean sea level will rise by 0.5–2.2 m during the 21st century. By quantifying a best estimate of scientific uncertainty, the fusion caters to diverse users.
Effect of cardiovascular diseases on brain functional changes and cognition: a systematic review of fMRI studies
Authors: Humayra Syeda , Yahya Noorazrul , Ning Chai Jia , Mir Imtiyaz Ali , Mohamed Abdul Latiff , Manan Hanani Abdul
Published: March 2024

Background Functional magnetic resonance imaging (fMRI) is a useful tool to evaluate brain inefficiencies secondary to cardiovascular diseases (CVDs); nevertheless, limited fMRI studies have been conducted to investigate the effect of CVD on brain functional changes and cognition. This systematic review aims to explore, synthesise, and report the fMRI outcomes and cognitive changes in patients with CVDs. Methods Two reviewers independently searched published literature until August 2023 on ScienceDirect, PubMed, Web of Science, and ClinicalTrials.gov. A total of 22 eligible studies were considered for full-text screening, of which 9 were included in this review. The methodological quality was assessed by mixed methods appraisal tool and reported as empirically fair. Results Among the 312 CVD subjects, aged between 49.90 ± 6.10 to 72.20 ± 5.70 years, majority had coronary heart diseases (n = 153, 40.04%) and hypertension (n = 188, 60.26%), and approximately half of them were females (n = 157, 50.32%). Based on the qualitative synthesis, CVD subjects have increased cognitive decline and poorer task performance (reduced Mini-Mental State Examination/Montreal Cognitive Assessment, lower mean 2-back task scores, and slower reaction time). Results also indicate impaired brain activity at supplementary motor area associated with poor ejection fraction, and reduced default mode network suppression linked to high low-density lipoprotein cholesterol; lower regional homogeneity and amplitude of low-frequency fluctuation values; and reduced functional connectivity. Conclusion It can be extrapolated that CVDs tend to alter brain network connectivity and result in cognitive impairment. However, for future imaging studies, more stringent and homogenous demographic data are highly recommended.
Skeletal Muscle Stem Cells Modulate Niche Function in Duchenne Muscular Dystrophy through YY1-CCL5 Axis
Authors: Wang Huating , Li Yang , Li Chuhan , Sun Qiang , Chen Fengyuan , Cheung Yeelo , Zhao Yu , Xie Ting , Chazaud Bénédicte , Sun Hao
Published: March 2024

Stem cell activity is known to be tightly regulated by both intrinsic and extrinsic pathways but less is known about whether and how stem cells modulate their niche microenvironment. Adult skeletal muscle stem cells (MuSCs) are indispensable for muscle regeneration and also tightly regulated by macrophages (MPs) and fibro-adipogenic progenitors (FAPs) in the niche. Deregulated MuSC/MP/FAP interactions and the ensuing inflammation and fibrosis are hallmarks of dystrophic muscle. Here in this study we demonstrate that intrinsic deletion of transcription factor YY1 in MuSCs exacerbates dystrophic pathologies by altering the cellular composition and heterogeneity of MPs and FAPs. Further analysis reveals that the YY1 loss induces the expression of immune genes in MuSCs, including Ccl5. Augmented secretion of CCL5 from MuSCs promotes the recruitment of MPs via CCL5/CCR5 mediated crosstalk, which subsequently hinders the apoptosis and clearance of FAPs through elevated TGFβ1 accumulation. Maraviroc mediated pharmacological blockade of the CCL5/CCR5 axis effectively mitigates muscle dystrophy and improves muscle performance. Lastly, we further demonstrate that YY1 represses Ccl5 transcription in MuSCs by directly binding to its enhancer thus facilitating promoter-enhancer looping. Altogether, our study has demonstrated the previously unappreciated role of MuSCs in actively shaping their niche microenvironment through secreting immunomodulatory cytokines and has also provided novel insight into the therapeutic intervention of muscle dystrophy.
Allelopathic effects of Stem Aqueous Extract of Lepidium didymum L. against Lens culinaris and Melilotus alba
Authors: Shadab MO , Parveen Uzma , Ain Quratul , Akhtar Nazish , Khan Mumayyaza , Siddiqui M.B.
Published: March 2024

Allelopathy involves plants releasing allelochemicals, inhibiting nearby plants' growth and influencing their physiological and morphological characteristics. Donor plants with allelopathic capabilities dominate, impacting the survival of other plant species. The effect of Lepidium didymum stem aqueous extracts (SAE) on Lens culinaris and Melilotus alba was investigated in this study. The experiment involved extracting compounds from the stems of Lepidium didymum and applying varying concentrations (0.5, 1, 2, and 4%) of these stem extracts to test plant seeds and seedlings. Multiple parameters, including germination percentage, growth parameters, and biochemical activities, were measured and compared against the control group. Germination percentage, seedling growth, seedling length, fresh and dry biomass, chlorophyll, and carotenoid content decreased notably, especially at higher concentrations (4%), while proline content increased in a concentration-dependent manner. In 2021–2022, the experiment was carried out in the allelopathy laboratory department of Botany Aligarh Muslim University, Aligarh. Scanning electron microscopy revealed ultrastructural abnormalities in the roots of the treated plants as compared to the control. Using GCMS analysis, 32 volatile chemicals were found in the methanolic extract of the stem. The compounds found in the major amounts are benzyl nitrile (291.19%), lauric acid (7.86%), benzene acetic acid (6.44%), 11-bromoundecanoic acid (7.36%), palmitic acid (4.85%), dodecanoic acid (4.80%), menthol, trans-1,3, cis-1,4 (3.28%), 11-bromoundecanoic acid (7.36%), and linolenic acid (8.64%). These compounds may be responsible for imparting an allelopathic effect on the test species, Lens culinaris and Melilotus alba. Our study revealed that the stem of L. didymum possesses a high concentration of water-soluble allelochemicals, which are thought to have reduced test plants’ growth and can be used as potential weedicides.
Synthesis and Characterization of Heterocyclic Compounds from Indole Butanoic Acid: Comprehensive Evaluation of Antibacterial and Anticancer Activate
Authors: Abdelzaher M. A. , Ali Azhar H. , Saleh Mohanad Yakdhan , Owaid Khalid Ahmed , Saied Shakir Mahmood , Abdelzaher Heba. G.
Published: March 2024

Focus of this study is on the use of the hydrazone compound (3) (N-(4-bromobenzylidene)-4-(1H-indol-3-yl) butane hydrazide), which was previously prepared from the reaction of the compound p-bromobenzaldehyde with the corresponding hydrazide (2) , as an intermediate compound for the synthesis of azetidine, thiazolidine, tetrazole, oxadiazole and phthalazine heterocyclic compounds through its reaction with some cyclic reagents and catalysts such as chloro acetyl chloride, thioglycolic acid, sodium-azid, lead dioxide and Hydrogen chloride gas. The prepared compounds were characterized using physical properties and also spectroscopic methods such as infrared spectroscopy, nuclear magnetic resonance spectra of the proton and the isotope of carbon13 as well as mass spectrometry, which accurately identified the proposed structures of the prepared compounds. The identity of the prepared compounds was determined using physical and spectroscopic properties, where infrared and 1HNMR spectroscopy of the proton as well as carbon13 were used in addition to using mass spectrometry to verify the validity of the prepared structures. Conclusions: Also, the biological antibacterial evaluation of the compounds (4-8) was conducted and it gave a good result compared to the drug (8) used as a reference for the control, The MTT test was performed on the healthy and cancerous cells of the compounds (4,5,8) and gave an excellent result for the compound (8).
Implications of Zoning Ordinances for Rural Utility-Scale Solar Deployment and Power System Decarbonization in the Great Lakes Region
Authors: Owusu-Obeng Papa Yaw , Mills Sarah , Craig Michael
Published: March 2024

Local zoning ordinances across the United States have the impact of restricting development of energy infrastructure, including utility-scale solar photovoltaics. While these ordinances may be developed for legitimate purposes to protect public health and safety, they could impede or increase costs of power sector decarbonization. We quantify the role of utility-scale solar zoning ordinances on power sector decarbonization across the Great Lakes region (Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin) by integrating 6,300 rural community zoning ordinances into a power system planning model. Relative to no ordinances, solar zoning ordinances reduce total potential deployment of solar PV by 52% (or 1.6 TW) across our region. Currently, however, the biggest zoning barrier to deployment is zoning ordinances which are silent on utility-scale solar. Deployment restrictions translate to up to 4 GW greater investment needs and 5.6% greater PV investment costs to achieve a 10% PV generation target. Starker shifts occur at the state level, e.g. Wisconsin sees a 40% reduction in PV investments due to zoning restrictions. Our results underscore the need for planning that aligns local zoning laws with state and regional goals.
Investigation of Thermodynamic Properties and Stability of Metal Oxide (CuO and Al 2 O 3 )/Deionized Water Nanofluids for Enhanced Heat Transfer Applications
Authors: Safir Nadhum Hussen , Razlan Zuradzman Mohamad , Ramasamy Girrimuniswar , Bakar Shahriman Abu , Abdullah Mohd Zulkifly
Published: March 2024

This research investigates nanofluids' thermodynamic properties and stability, specifically their potential to improve heat transfer in various applications. The study examines the methods used to characterise and measure the stability of two nanofluids: Al2O3/deionized water and CuO/deionized water nanofluids. These nanofluids are created using a two-step process involving magnetic stirring and ultrasonication. The stability of the nanofluids is evaluated quantitatively using standard deviation analysis, which reveals that CuO (80 nm)/deionized water nanofluids have better stability compared to Al2O3 (80 nm)/deionized water nanofluids. Additionally, the research explores how variables such as temperature, volume concentration, and nanoparticle type affect the properties of nanofluids under both static and dynamic conditions. In the static phase, the thermophysical properties of the fluids, including thermal conductivity, viscosity, and specific heat, are measured. In the dynamic phase, a setup resembling a heat exchanger is designed to determine the heat transfer rate. The study's findings show that CuO (80 nm)/deionised water nanofluids have the highest thermal conductivity compared to Al2O3 (80 nm)/deionised water nanofluids under the same conditions. Furthermore, viscosity tests demonstrate that increasing the volume concentration of nanoparticles increases viscosity while increasing temperature decreases viscosity. Lastly, the study reveals that CuO (80 nm)/deionized water nanofluids experience the greatest reduction in specific heat and heat transfer rate compared to Al2O3/deionized water nanofluids.
Golgi apparatus proteome deciphering in living cells enabled by aggregation-induced emission luminogen-mediated photocatalytic proximity labeling (AIE-PhoPL)
Authors: Jiang Bo , Wang He , Guo Yanli , Chen Yuncong , Liang Zhen , Liu Wenwen , Guo Zijian , Zhang Yu-Kui , Zhang Lihua
Published: March 2024

As a central platform of proteins sorting and signal docking, in situ Golgi apparatus (GA) proteome mapping is critical for elucidating relevant biological events. However, chemical proteomic dissection of GA is poorly studied owing to the lack of efficient labeling methods. Herein, we described an aggregation-induced emission luminogen-mediated photocatalytic proximity labeling strategy (AIE-PhoPL) that allowed dynamic profiling of GA proteome with high spatiotemporal precision in a native context. With the GA-targeting photocatalyst based on aggregation-induced emission luminogen (AIEgen), the proteins were activated and labeled locally in Golgi with high efficiency under control of visible light, enabling spatiotemporally resolved modifying of histidine and tyrosine residues. Upon validation in living HeLa cells which determined a significant portion of Golgi-associated proteins with 78% specificity, we applied AIE-PhoPL to dynamic proteome mapping of brain metastatic lung cancer cells and revealed the underlying roles GA played in signal transduction and extracellular matrix organization during cancer metastasis. This work provides a powerful tool to break out the dilemma for chemical labeling of GA proteome in living cells and fuels the research on diversification of controllable chemical probes for subcellular proteome labeling.
Low-cost and precise traditional Chinese medicinal tree pest and disease monitoring using UAV RGB image only
Authors: Guo Haoran , Cheng Yuhua , Liu Jun , Wang Zhihu
Published: March 2024

Accurate and timely pest and disease monitoring during the cultivation process of traditional Chinese medicinal materials is crucial for ensuring optimal growth, increased yield, and enhanced content of effective components. This paper focuses on the essential requirements for pest and disease monitoring in a planting base of Cinnamomum Camphora var. Borneol (CCB) and presents a solution using unmanned aerial vehicle (UAV) images to address the limitations of real-time and on-site inspections. In contrast to existing solutions that rely on advanced sensors like multispectral or hyperspectral sensors mounted on UAVs, this paper utilizes visible light sensors directly. It introduces an ensemble learning approach for pest and disease monitoring of CCB trees based on RGB-derived vegetation indices and a combination of various machine learning algorithms. By leveraging the feature extraction capabilities of multiple algorithms such as RF, SVM, KNN, GBDT, XGBoost, GNB, and ELM, and incorporating morphological filtering post-processing and genetic algorithms to assign weights to each classifier for optimal weight combination, a novel ensemble learning strategy is proposed to significantly enhance the accuracy of pest and disease monitoring of CCB trees. Experimental results validate that the proposed method can achieve precise pest and disease monitoring with reduced training samples, exhibiting high generalization ability. It enables large-scale pest and disease monitoring at a low cost and high precision, thereby contributing to improved precision in the cultivation management of traditional Chinese medicinal materials.
Deep Learning captures the effect of epistasis in multifactorial diseases
Authors: Perelygin Vladislav , Kamelin Alexey , Syzrantsev Nikita , Shaheen Layal , Kim Anna , Plotnikov Nikolay , Ilinskaya Anna , Ilinsky Valery , Rakitko Alexander , Poptsova Maria
Published: March 2024

Background
Polygenic risk score (PRS) prediction is widely used to assess the risk of diagnosis and progression of many diseases. Routinely, the weights of individual SNPs are estimated by the linear regression model that assumes independent and linear contribution of each SNP to the phenotype. However, for complex multifactorial diseases such as Alzheimer's disease, diabetes, cardiovascular disease, cancer, and others, association between individual SNPs and disease could be non-linear due to epistatic interactions. The aim of the presented study is to explore the power of non-linear machine learning algorithms and deep learning models to predict the risk of multifactorial diseases with epistasis.
Results
First, we tested ensemble tree methods and deep learning neural networks against LASSO linear regression model on simulated data with different types and strength of epistasis. The results showed that with the increase of strength of epistasis effect, non-linear models significantly outperform linear. Then the higher performance of non-linear models over linear was confirmed on real genetic data for multifactorial phenotypes such as obesity, type 1 diabetes, and psoriasis. From non-linear models, gradient boosting appeared to be the best model in obesity and psoriasis while deep learning methods significantly outperform linear approaches in type 1 diabetes.
Conclusions
Overall, our study underscores the efficacy of non-linear models and deep learning approaches in more accurately accounting for the effects of epistasis in simulations with specific configurations and in the context of certain diseases.