bluuebunny/crossref_metadata_2025 huggingface dataset:
Data from Alteration of Cell–Cell and Cell–Matrix Adhesion in Urothelial Cells: An Oncogenic Mechanism for Mutant FGFR3
Authors: di Martino Erica , Kelly Gavin , Roulson Jo-An , Knowles Margaret A.
Published: January 2024

Abstract
Activating mutations of FGFR3 are a common and early event in bladder cancer. Ectopic expression of mutant FGFR3 in normal urothelial cells has both pro-proliferative and antiapoptotic effects at confluence, suggesting that mutant cells are insensitive to cell–cell contact inhibition. Herein, detailed analysis revealed that these cells have reduced cell–cell adhesion, with large intercellular spaces observable at confluence, and diminished cell–substrate adhesion to collagen IV, collagen I, and fibronectin. These phenotypic alterations are accompanied by changes in the expression of genes involved in cell adhesion and extracellular matrix remodeling. Silencing of endogenous mutant FGFR3 in bladder cancer cells induced converse changes in transcript levels of CDH16, PLAU, MMP10, EPCAM, TNC, and HAS3, confirming them as downstream gene targets of mutant FGFR3. Overexpression of EPCAM, HAS3, and MMP10 transcripts was found in a large fraction of primary bladder tumors analyzed, supporting their key role in bladder tumorigenesis in vivo. However, no correlation was found between their protein and/or mRNA expression and FGFR3 mutation status in tumor specimens, indicating that these genes may be targeted by several converging oncogenic pathways. Overall, these results indicate that mutant FGFR3 favors the development and progression of premalignant bladder lesions by altering key genes regulating the cell–cell and cell–matrix adhesive properties of urothelial cells.

Implications: The ability of mutant FGFR3 to drive transcriptional expression profiles involved in tumor cell adhesion suggests a mechanism for expansion of premalignant urothelial lesions. Mol Cancer Res; 13(1); 138–48. ©2014 AACR.
Data from Prostate Cancer Genetic-susceptibility Locus on Chromosome 20q13 is Amplified and Coupled to Androgen Receptor-regulation in Metastatic Tumors
Authors: Labbé David P. , Nowak Dawid G. , Deblois Geneviève , Lessard Laurent , Giguère Vincent , Trotman Lloyd C. , Tremblay Michel L.
Published: January 2024

Abstract
The 20q13 chromosomal region has been previously identified as the hereditary prostate cancer genetic-susceptibility locus on chromosome 20 (HPC20). In this study, the 20q13 region was shown to be frequently co-amplified with the androgen receptor (AR) in metastatic prostate cancer. Furthermore, the AR signaling axis, which plays an essential role in the pathogenesis of prostate cancer, was demonstrated to be central to the regulation of the 20q13 common amplified region (CAR). High-resolution mapping analyses revealed hot spots of AR recruitment to response elements in the vicinity of most genes located on the 20q13 CAR. Moreover, amplification of AR significantly co-occurred with CAR amplification on 20q13 and it was confirmed that the majority of AR-bound genes on the 20q13 CAR were indeed regulated by androgens. These data reveal that amplification of the AR is tightly linked to amplification of the AR-regulated CAR region on 20q13. These results suggest that the cross-talk between gene amplification and gene transcription is an important step in the development of castration-resistant metastatic disease.

Implications: These novel results are a noteworthy example of the cross-talk between gene amplification and gene transcription in the development of advanced prostate cancer.

Visual Overview: http://mcr.aacrjournals.org/content/early/2014/02/07/1541-7786.MCR-13-0477/F1.large.jpg. Mol Cancer Res; 12(2); 184–9. ©2013 AACR.
TABLE 1 from Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer–Treated with Neoadjuvant Systemic Therapy
Authors: De Schepper Maxim , Nguyen Ha-Linh , Richard François , Rosias Louise , Lerebours Florence , Vion Roman , Clatot Florian , Berghian Anca , Maetens Marion , Leduc Sophia , Isnaldi Edoardo , Molinelli Chiara , Lambertini Matteo , Grillo Federica , Zoppoli Gabriele , Dirix Luc , Punie Kevin , Wildiers Hans , Smeets Ann , Nevelsteen Ines , Neven Patrick , Vincent-Salomon Anne , Larsimont Denis , Duhem Caroline , Viens Patrice , Bertucci François , Biganzoli Elia , Vermeulen Peter , Floris Giuseppe , Desmedt Christine
Published: January 2024

Baseline clinical and pathologic characteristics of patients in the entire cohort and in each of the breast cancer subgroups
Supplementary Table 2 from Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer–Treated with Neoadjuvant Systemic Therapy
Authors: De Schepper Maxim , Nguyen Ha-Linh , Richard François , Rosias Louise , Lerebours Florence , Vion Roman , Clatot Florian , Berghian Anca , Maetens Marion , Leduc Sophia , Isnaldi Edoardo , Molinelli Chiara , Lambertini Matteo , Grillo Federica , Zoppoli Gabriele , Dirix Luc , Punie Kevin , Wildiers Hans , Smeets Ann , Nevelsteen Ines , Neven Patrick , Vincent-Salomon Anne , Larsimont Denis , Duhem Caroline , Viens Patrice , Bertucci François , Biganzoli Elia , Vermeulen Peter , Floris Giuseppe , Desmedt Christine
Published: January 2024

Supplementary Table 2 shows clinicopathological characteristics of the entire cohort and the Leuven sub-cohort.
Supplementary Figure 9 from Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer–Treated with Neoadjuvant Systemic Therapy
Authors: De Schepper Maxim , Nguyen Ha-Linh , Richard François , Rosias Louise , Lerebours Florence , Vion Roman , Clatot Florian , Berghian Anca , Maetens Marion , Leduc Sophia , Isnaldi Edoardo , Molinelli Chiara , Lambertini Matteo , Grillo Federica , Zoppoli Gabriele , Dirix Luc , Punie Kevin , Wildiers Hans , Smeets Ann , Nevelsteen Ines , Neven Patrick , Vincent-Salomon Anne , Larsimont Denis , Duhem Caroline , Viens Patrice , Bertucci François , Biganzoli Elia , Vermeulen Peter , Floris Giuseppe , Desmedt Christine
Published: January 2024

Supplementary Figure 9 shows potential non-linear association of RCB score with sTIL.
Supplementary Figure 8 from Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer–Treated with Neoadjuvant Systemic Therapy
Authors: De Schepper Maxim , Nguyen Ha-Linh , Richard François , Rosias Louise , Lerebours Florence , Vion Roman , Clatot Florian , Berghian Anca , Maetens Marion , Leduc Sophia , Isnaldi Edoardo , Molinelli Chiara , Lambertini Matteo , Grillo Federica , Zoppoli Gabriele , Dirix Luc , Punie Kevin , Wildiers Hans , Smeets Ann , Nevelsteen Ines , Neven Patrick , Vincent-Salomon Anne , Larsimont Denis , Duhem Caroline , Viens Patrice , Bertucci François , Biganzoli Elia , Vermeulen Peter , Floris Giuseppe , Desmedt Christine
Published: January 2024

Supplementary Figure 8 shows descriptive data of pCR rates according to several pathological features.
Supplementary Figure 4 from Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer–Treated with Neoadjuvant Systemic Therapy
Authors: De Schepper Maxim , Nguyen Ha-Linh , Richard François , Rosias Louise , Lerebours Florence , Vion Roman , Clatot Florian , Berghian Anca , Maetens Marion , Leduc Sophia , Isnaldi Edoardo , Molinelli Chiara , Lambertini Matteo , Grillo Federica , Zoppoli Gabriele , Dirix Luc , Punie Kevin , Wildiers Hans , Smeets Ann , Nevelsteen Ines , Neven Patrick , Vincent-Salomon Anne , Larsimont Denis , Duhem Caroline , Viens Patrice , Bertucci François , Biganzoli Elia , Vermeulen Peter , Floris Giuseppe , Desmedt Christine
Published: January 2024

Supplementary Figure 4 shows an overview of tumor emboli assessment.
Supplementary Figure 14 from Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer–Treated with Neoadjuvant Systemic Therapy
Authors: De Schepper Maxim , Nguyen Ha-Linh , Richard François , Rosias Louise , Lerebours Florence , Vion Roman , Clatot Florian , Berghian Anca , Maetens Marion , Leduc Sophia , Isnaldi Edoardo , Molinelli Chiara , Lambertini Matteo , Grillo Federica , Zoppoli Gabriele , Dirix Luc , Punie Kevin , Wildiers Hans , Smeets Ann , Nevelsteen Ines , Neven Patrick , Vincent-Salomon Anne , Larsimont Denis , Duhem Caroline , Viens Patrice , Bertucci François , Biganzoli Elia , Vermeulen Peter , Floris Giuseppe , Desmedt Christine
Published: January 2024

Supplementary Figure 14 shows analyses of the association of sTIL with DRFS.
Plus noise unlock
Authors: Fradkin Meesh
Published: January 2024

What happens when speech synthesis applications are incompatible with certain software? This essay considers how inaccessibility within the software and programming language Max is sonically, aesthetically, culturally, and ideologically amplified through a case study of “plus noise unlock,” which is the sound made by the author’s computer when she attempts to use a screen reader within a patcher window.
Gegen wen ist Kuria Doxa 33 gerichtet?
Authors: Robitzsch Jan Maximilian
Published: January 2024

Scholars usually understand Κύρια Δόξα (ΚΔ) 33 as an antiplatonic polemic. This paper denies the communis opinio. First, it argues for an ontological reading of the maxim according to which justice (understood as virtue) is not a body but a property. Second, it shows that the Stoics hold the very thesis disputed in ΚΔ 33, namely that virtue is a body. This makes the Stoa the natural target of the maxim. Finally, the paper deals with De rerum natura I.464-482: here Lucretius criticizes nameless opponents with regard to the thesis that events are to be understood as bodies. If these opponents can be identified with the Stoics, as is usually assumed, there is further evidence besides ΚΔ 33 that the Epicureans engaged with the Stoic thesis of corporealism.
Incidence and risk factors of early onset VOD/SOS differ in younger vs older adults after stem cell transplantation
Authors: Marcoux Curtis , Saliba Rima M. , Wallis Whitney , Khazal Sajad , Ragoonanan Dristhi , Rondon Gabriela , Tewari Priti , Popat Uday , Oran Betul , Olson Amanda , Bashir Qaiser , Qazilbash Muzaffar , Alousi Amin , Hosing Chitra , Nieto Yago , Alatrash Gheath , Marin David , Rezvani Katayoun , Khouri Issa , Srour Samer , Champlin Richard , Shpall Elizabeth , Kebriaei Partow
Published: January 2024

Veno-occlusive disease (VOD) is a rare but potentially life-threatening complication after allogeneic hematopoietic stem cell transplantation (allo-SCT). Although increasing awareness and modern transplant techniques have mitigated risk, the interaction of historic risk factors in the current era with posttransplant cyclophosphamide (PTCy) is unknown. We performed a retrospective single-center analysis of adult patients aged ≥18 years undergoing allo-SCT (N = 1561) using predominately PTCy as graft-versus-host disease (GVHD) prophylaxis (72%). We found a higher rate of VOD at 16.8% (20 of 119) in those aged ≤25 years compared with 3.8% (55 of 1442) in those aged >25 years, with unique predictors of VOD within each cohort. Multivariate classification and regression tree (CART) analysis confirmed age as the primary independent determinant of the rate of VOD. Among patients aged 18 to 25 years, disease risk index (DRI; 31% with high/very high DRI vs 12% low/intermediate DRI; P = .03) and prior lines of chemotherapy (24% with >1 vs 6% with ≤1; P = .03) were the strongest predictors of VOD. Incidence of VOD in patients aged >25 years of age consistently ranged between 3% and 5% across most risk factors evaluated, with only hepatic factors (baseline elevation of bilirubin, aspartate transferase, alanine aminotransferase) or gemtuzumab exposure associated with increased rates of VOD. There was no significant difference in rates of VOD in those receiving PTCy compared with those receiving alternate GVHD prophylaxis. Our data highlight the differences in incidence and predictors of VOD between younger (≤25) and older (>25) adults undergoing allo-SCT.
The role of point-of-care ultrasound (POCUS) imaging in clinical outcomes during cardiac arrest: a systematic review
Authors: Zaki Hany A. , Iftikhar Haris , Shaban Eman E. , Najam Mavia , Alkahlout Baha Hamdi , Shallik Nabil , Elnabawy Wael , Basharat Kaleem , Azad Aftab Mohammad
Published: January 2024

Background

Cardiac arrest in hospital and out-of-hospital settings is associated with high mortality rates. Therefore, a bedside test that can predict resuscitation outcomes of cardiac arrest patients is of great value. Point-of-care ultrasound (POCUS) has the potential to be used as an effective diagnostic and prognostic tool during cardiac arrest, particularly in observing the presence or absence of cardiac activity. However, it is highly susceptible to “self-fulfilling prophecy” and is associated with prolonged cardiopulmonary resuscitation (CPR), which negatively impacts the survival rates of cardiac arrest patients. As a result, the current systematic review was created to assess the role of POCUS in predicting the clinical outcomes associated with out-of-hospital and in-hospital cardiac arrests.

Methods

The search for scientific articles related to our study was done either through an electronic database search (i.e., PubMed, Medline, ScienceDirect, Embase, and Google Scholar) or manually going through the reference list of the relevant articles. A quality appraisal was also carried out with the Quality Assessment of Diagnostic Accuracy Studies tool (QUADAS-2), and the prognostic test performance (sensitivity and sensitivity) was tabulated.

Results

The search criteria yielded 3984 articles related to our topic, of which only 22 were eligible for inclusion. After reviewing the literature, we noticed a wide variation in the definition of cardiac activity, and the statistical heterogeneity was high; therefore, we could not carry out meta-analyses. The tabulated clinical outcomes based on initial cardiac rhythm and definitions of cardiac activity showed highly inconsistent results.

Conclusion

POCUS has the potential to provide valuable information on the management of cardiac arrest patients; however, it should not be used as the sole predictor for the termination of resuscitation efforts.
Severe hemothorax due to traumatic fracture of thoracic vertebra
Authors: Ozono Keigo , Son Kiwa , Momii Kenta , Morifuji Yoshihiro , Ikenaga Naoki , Nakamura Masafumi
Published: January 2024

Background

Hemothorax occurs in approx. 0.4% of all chest injury patients, but hemothorax due to a thoracic vertebral fracture is rare.

Case presentation

A 76-year-old Japanese man was transported to our hospital for right hemothorax due to a car accident. We performed emergency hemostasis surgery and tried to stop the bleeding by several methods, but it was difficult to control the bleeding because the bleeding point was an artery branch that runs in front of the vertebral body.

Conclusion

It is important to be aware that a fractured vertebra can damage the aorta's arterial branch and follow a severe course.
Plant effects on microbiome composition are constrained by environmental conditions in a successional grassland
Authors: Mészárošová Lenka , Kuťáková Eliška , Kohout Petr , Münzbergová Zuzana , Baldrian Petr
Published: January 2024

Background

Below-ground microbes mediate key ecosystem processes and play a vital role in plant nutrition and health. Understanding the composition of the belowground microbiome is therefore important for maintaining ecosystem stability. The structure of the belowground microbiome is largely determined by individual plants, but it is not clear how far their influence extends and, conversely, what the influence of other plants growing nearby is.

Results

To determine the extent to which a focal host plant influences its soil and root microbiome when growing in a diverse community, we sampled the belowground bacterial and fungal communities of three plant species across a primary successional grassland sequence. The magnitude of the host effect on its belowground microbiome varied among microbial groups, soil and root habitats, and successional stages characterized by different levels of diversity of plant neighbours. Soil microbial communities were most strongly structured by sampling site and showed significant spatial patterns that were partially driven by soil chemistry. The influence of focal plant on soil microbiome was low but tended to increase with succession and increasing plant diversity. In contrast, root communities, particularly bacterial, were strongly structured by the focal plant species. Importantly, we also detected a significant effect of neighbouring plant community composition on bacteria and fungi associating with roots of the focal plants. The host influence on root microbiome varied across the successional grassland sequence and was highest in the most diverse site.

Conclusions

Our results show that in a species rich natural grassland, focal plant influence on the belowground microbiome depends on environmental context and is modulated by surrounding plant community. The influence of plant neighbours is particularly pronounced in root communities which may have multiple consequences for plant community productivity and stability, stressing the importance of plant diversity for ecosystem functioning.
Physical comorbidities in people with severe mental disorders: promises and future challenges
Authors: Sartorius N.
Published: January 2024

The comorbidity of mental and physical disorders is gradually becoming recognized as a major problem for health care. Its public health importance is vast and growing for a variety of reasons including the extension of life expectancy, the imperfection of currently available treatments of mental and many physical disorders and the tendency of fragmentation of medicine into ever more limited specialties. The problems related to comorbidity are also rapidly increasing in low- and middle-income countries where in addition to the issues mentioned above there is also a scarcity of means to deal with them.

The presentation will remind the audience of the complexity of the problems and draw attention to action that could be taken by public health authorities and the medical profession in the areas of teaching, organization of service and research.

Disclosure of Interest

None Declared
Πίνοντας και χορεύοντας τη Νικαριά μ' ένα βιολί
Authors: Φατούρου Αικατερίνη
Published: January 2024

Η διατριβή αποτελεί προϊόν εθνομουσικολογικής έρευνας, η οποία εστιάζει στις τρεις θεμελιώδεις διαστάσεις του παραδοσιακού σχήματος "μουσική, χορός, συλλογικό πίνειν", και στους τρόπους με τους οποίους οι εν λόγω διαστάσεις συνομιλούν μεταξύ τους, συνδιαμορφώνοντας και μετασχηματίζοντας την επιτέλεση του γλεντιού, όπως αποτυπώνεται σε διαφορετικούς τόπους και χρόνους της ικαριακής πραγματικότητας. Μέσα από την επιτόπια έρευνα, συλλογή και ανάλυση των εθνομουσικολογικών και εθνοχορολογικών δεδομένων όπως εμφανίζονται σε τοπικά, υπερτοπικά και διασπορικά παραδείγματα ικαριώτικων γλεντιών, η διατριβή διερευνά το ρόλο τους στην πολιτισμική κατασκευή της κοινότητας, αλλά και την επίδραση τους ως στοιχεία που οδηγούν επιτελεστικά στην ανάδυση μιας διευρυμένης 'γλεντικής' κοινότητας με εφήμερα και ετερόκλητα πολιτισμικά χαρακτηριστικά, αναδεικνύοντας θέματα ταυτότητας, φύλου, διαλογικής επικοινωνίας και συμμετοχής. Ταυτόχρονα, μέσα από τον λόγο των ντόπιων μουσικών, χορευτών και ακροατών, φωτίζεται ποικιλοτρόπως η πορεία της ικαριώτικης μουσικοχορευτικής κουλτούρας στο χρόνο, και οι μετασχηματισμοί που έχει υποστεί σε μουσικολογικό και συμβολικό επίπεδο, έχοντας ως κύριο εθνογραφικό παράδειγμα τον δημοφιλή ικαριώτικο μουσικοχορευτικό σκοπό, και το σύγχρονο ρόλο του ως αυτόνομο εμπορευματοποιημένο πολιτισμικό προϊόν, το οποίο αναδεικνύεται στους τόπους του γλεντιού, αλλά και εξωεδαφικά, σε μεσοποιημένα α-χρονικά και α-τοπικά περιβάλλοντα, όπως τα ΜΜΕ, το διαδίκτυο και τα μέσα κοινωνικής δικτύωσης. Στο πλαίσιο αυτό, φωτίζεται ποικιλοτρόπως ο διάλογος περί ‘παραδοσιακών’ και ‘νεωτερικών’ μουσικοχορευτικών επιτελέσεων, παρέχοντας μία διευρυμένη οπτική στο θέμα της ικαριώτικης μουσικοχορευτικής παράδοσης και του Εαυτού που δρα και συνδιαλέγεται μέσα και γύρω από αυτήν, στη σύγχρονη παγκοσμιοποιημένη εποχή.
Μελέτη, σχεδίαση & υλοποίηση ηλεκτρονικών διατάξεων για εφαρμογές μετρήσεων, απόρριψης παρεμβολών και αποδοτικής συγκομιδής ενέργειας από ηλεκτρομαγνητικά πεδία
Authors: Ταμπουρατζής Μανόλης
Published: January 2024

Η έρευνα της παρούσας διδακτορικής διατριβής εντάσσεται στο ευρύτερο πεδίο των ηλεκτρομαγνητικών εφαρμογών και αποτελείται από τρία επιμέρους τμήματα, διακριτά μεταξύ τους. Στο πρώτο συγκαταλέγονται τα Κεφάλαια 1,2,3 και 4, όπου παρουσιάζουν τις ηλεκτρονικές διατάξεις που αναπτύχθηκαν για σκοπούς συγκομιδής ενέργειας από χαρακτηριστικές περιοχές του ηλεκτρομαγνητικού φάσματος. Σε αυτή την ενότητα, επιχειρήθηκε η προσπάθεια συγκομιδής ενέργειας: α) από εξαιρετικά χαμηλές συχνότητες (ELF) προερχόμενες από τη λειτουργία του δημόσιου δικτύου διανομής ηλεκτρικής ενέργειας (των 50Hz), β) από τη ραδιοφωνική ζώνη των μεσαίων κυμάτων (MW), καθώς και γ) από την περιοχή λειτουργίας των σύγχρονων ασύρματων συστημάτων κινητών επικοινωνιών (με έμφαση στα συστήματα DCS 1800, UMTS 2100 και LTE). Το ηλεκτρονικό σύστημα διαχείρισης ισχύος που αναπτύχθηκε εφαρμόζει ευέλικτες μεθόδους αποδοτικής αποθήκευσης και διαχείρισης ενέργειας προερχόμενη από τη συγκομιδή, για αξιοποίηση από συσκευές υπέρ-χαμηλής κατανάλωσης (ultra-low power), όπως ο κόμβος ενός ασύρματου αισθητήρα. Η προτεινόμενη διάταξη ενσωματώνει μια τεχνική βελτίωσης συγκομιδής ενέργειας ως απόρροια των εργαστηριακών δοκιμών στα πλαίσια της παρούσας έρευνας. Η μεγιστοποίηση συγκομιδής έγκειται στην εναλλαγή των στοιχείων αποθήκευσης (Tank Capacitors) του συστήματος, αξιοποιώντας με τον καλύτερο δυνατό τρόπο την αυξημένη απόδοση του στη μεταβατική κατάσταση λειτουργίας (Transient State) σε αντίθεση με τον σχεδόν μηδενικό ρυθμό απορρόφησης ενέργειας στην κατάσταση πλήρους φόρτισης (Steady State). Ακολούθως, το δεύτερο τμήμα της διατριβής αποτελείται από το 5o Κεφάλαιο που είναι αφιερωμένο στην ανάπτυξη ευρυζωνικών (Broadband) επίπεδων κεραιών μικρών διαστάσεων με χαρακτηριστικά απόρριψης ζώνης συχνοτήτων με σκοπό την αποφυγή παρεμβολών από ασύρματα συστήματα στενής ζώνης (Narrowband). Οι προτεινόμενες κεραίες δύναται να απορρίπτουν σήματα προερχόμενα από ασύρματα δίκτυα Wi-Fi (2.4GHz), δίκτυα Wi-Max και συστήματα κινητών επικοινωνιών 5G New Radio n78 (3.5GHz) καθώς επίσης και από στρατιωτικές υπηρεσίες που λειτουργούν στη συχνότητα των 3GHz, με ταυτόχρονη διατήρηση των ευρυζωνικών τους χαρακτηριστικών και των πανκατευθυντικών διαγραμμάτων ακτινοβολίας τους στην ζώνη λειτουργείας 1.5 έως 4 GHz. Tέλος, το τελευταίο τμήμα αποτελεί το 6o Κεφάλαιο, όπου παρατίθεται η μεθοδολογία υλοποίησης ηλεκτρονικών διατάξεων για τη μέτρηση της έντασης μαγνητικού πεδίου με έμφαση την περιοχή των εξαιρετικά χαμηλών συχνοτήτων (ELF). Τα προτεινόμενα ηλεκτρονικά συστήματα ενσωματώνουν νέες τεχνικές ασύρματης διασύνδεσης για την αποστολή μετρήσεων, αποτελώντας μια σύγχρονη ΙοΤ-EMF υλοποίηση, παρέχοντας στο χρήστη την εξ ‘αποστάσεως επιτήρηση των επιπέδων του εκάστοτε μετρούμενου μαγνητικού πεδίου.
HOW TO MEASURE THE LEVEL OF STAFF INVOLVEMENT
Authors: Kashtanova YEkatyerina , Lobacheva A. , Ashurbekov R.
Published: January 2024

The level of staff involvement is a very important tool for personnel management and business in general. Modern organizations often face the problem of insufficient efficiency of employees, lack of motivation to work. In most cases, the root of the difficulties lies in the lack of involvement of staff. Employers expect high results from their employees, but, unfortunately, pay little attention to the development of their interest in the work itself. In this regard, in their article, the authors emphasize the importance and significance of periodic monitoring of involvement and identification of the level of involvement and loyalty of staff. The authors of the article consider the indicators by which employers and HR specialists conduct such an assessment and offer ideas to strengthen employee engagement.
CLASSIFICATION AND APPROACHES TO CREATION OF STARTUP STUDIO IN UNIVERSITIES
Authors: Lunin A. , Il'chenko E.
Published: January 2024

The article is devoted to issues related to the development of project activities in educational institutions. In modern conditions, the activities of educational institutions are increasingly connected with entrepreneurship and business communities. Issues regarding the creation and development of Start-up studios in educational institutions are becoming especially relevant. When creating startup studios, it is important to understand the specifics of different types of startup studios and the parameters of their activities in order to correlate them with the goals of the educational institution and the project being implemented. An educational institution can choose for itself the most optimal Startup Studio model, taking into account the size of the educational institution, its territorial location, its financial and personnel capabilities. This article presents the results of a study on the classification of Startup Studios and concludes that for educational institutions the most optimal are University Startup Studios, which in recent years have been quite actively created, operating and bringing real innovative projects to educational institutions.
PROFESSIONAL SECTOR OF HUMAN RESOURCE MANAGEMENT IN RUSSIA: CURRENT STATE AND DEVELOPMENT PROSPECTS
Authors: Dolzhenko Svetlana , Dolzhenko Ruslan , Chudinovskih M. , Konovalova Valeriya , Fedotova M.
Published: January 2024

The modern labor market, on the one hand, shows significant stability in terms of the unemployment rate and other basic indicators, on the other, it demonstrates variability and adaptability in relation to current technologies and approaches. One of the important professional sectors of the labor market is the field of personnel management, because it is associated with direct work with employees, considering the needs and goals of the business. The purpose of the study is to study the labor market in the personnel management segment in reflection of several data and to highlight key trends and drivers of development of the professional field. The main research method is the analysis of materials and data from Rosstat, Headhunter, analytical reviews, and expert interviews. The work presents the results of an analysis of the labor market in the personnel management segment (as of the end of 2021), which showed that this professional field is an important component of the labor market, involving up to 1 million people who are engaged in various areas of work with personnel (from selection, personnel document flow, motivation, assessment, training, etc. to general personnel management and HR-business partnership). Understanding the directions of development of this segment makes it possible to assess the demand for professions in the field of personnel work and determine promising development goals, including opportunities for the professional development of young specialists.
CULTURE CORNER SECTION IN THE TEXTBOOK: INTEGRATIVE STUDYING THE ENGLISH LAGUAGE THROUGH STUDYING CULTURES OF ASIA PACIFIC REGION COUNTRIES
Authors: Dyundik Yuliya , Hlyzova Natal'ya
Published: January 2024

The article describes and analyzes a section of the textbook English Dimensions: Language, Region, Cultures (developed and published in 2023 at APR Regional Studies Department, Irkutsk State University, the authors are Yu.B. Dyundik, O.A. Kaverina, E.E. Kalish, M.V. Novosyolova, N.Yu. Khlyzova, A.V. Chaykisova). The section is based on information about cultural peculiarities of Asian-Pacific countries. The key countries are the USA, Russia, China, South Korea and Japan, the reason for that is what languages the students of this field of education study. In the article the authors share their experience of integrative way of teaching a foreign language (English) and foreign culture(s) to linguistic university students. It gives a variety of exercises which are basic for studying a foreign culture, such exercises develop relevant competencies, required to be effective and highly professional in their major, English. The authors believe that a foreign language (English in this case) can be considered an ideal platform to learn APR countries’ culture, as integration of a foreign language and cultures lets broaden knowledge and experience in almost any sphere, creates a highly-educated broadminded specialist and provides with the skills of analytical mind, creativity, and high level of critical thinking. A foreign language as a subject has a powerful integrative potential, moreover the core is knowledge about the world (about APR countries in this case) and communication are both a purpose and a means of studying.
Wielokulturowość a prawa kobiet. Rewizja koncepcji Susan Moller Okin
Authors: Banaś Monika
Published: January 2024

The chapter critically analyzes the postulates raised by Susan Okin in her three major works, written at different stages of her academic activity. The objective is not so much to show the evolution of a view ultimately questioning the apotheosis of the politics of multiculturalism, but to point out the misleading – because apparent (de facto non-existent) – correlation of multiculturalism and equality. The focus on the rights of minority groups (religious, cultural, ethno-national groups) has completely ignored the aspect of relations occurring at a fundamental level, between individuals, and especially where women are the subject/participant of these relations. The politics of multiculturalism promoted by, among others, J. Rawls or W. Kymlicka, according to Okin is a selective politics, omitting women’s rights. An idea on how to address this problem, still present in the third decade of the 21st century, is presented discussing Okin’s argumentation.
Research Roundup
Authors: Winter George
Published: January 2024

George Winter provides an overview of recently published articles that may be of interest to practice nurses. Should you wish to look at any of the papers in more detail, a full reference is provided.
Influence of initial check, information exchange, final accuracy check, reaction information nursing on the psychology of elderly with lung cancer
Authors: Jiang Cui , Ma Jing , He Wen , Zhang Hai-Ying
Published: January 2024

BACKGROUND

As one of the fatal diseases with high incidence, lung cancer has seriously endangered public health and safety. Elderly patients usually have poor self-care and are more likely to show a series of psychological problems.

AIM

To investigate the effectiveness of the initial check, information exchange, final accuracy check, reaction (IIFAR) information care model on the mental health status of elderly patients with lung cancer.

METHODS

This study is a single-centre study. We randomly recruited 60 elderly patients with lung cancer who attended our hospital from January 2021 to January 2022. These elderly patients with lung cancer were randomly divided into two groups, with the control group taking the conventional propaganda and education and the observation group taking the IIFAR information care model based on the conventional care protocol. The differences in psychological distress, anxiety and depression, life quality, fatigue, and the locus of control in psychology were compared between these two groups, and the causes of psychological distress were analyzed.

RESULTS

After the intervention, Distress Thermometer, Hospital Anxiety and Depression Scale (HADS) for anxiety and the HADS for depression, Revised Piper’s Fatigue Scale, and Chance Health Locus of Control scores were lower in the observation group compared to the pre-intervention period in the same group and were significantly lower in the observation group compared to those of the control group (P < 0.05). After the intervention, Quality of Life Questionnaire Core 30 (QLQ-C30), Internal Health Locus of Control, and Powerful Others Health Locus of Control scores were significantly higher in the observation and the control groups compared to the pre-intervention period in their same group, and QLQ-C30 scores were significantly higher in the observation group compared to those of the control group (P < 0.05).

CONCLUSION

The IIFAR information care model can help elderly patients with lung cancer by reducing their anxiety and depression, psychological distress, and fatigue, improving their tendencies on the locus of control in psychology, and enhancing their life qualities.
Accidental placement of venous return catheter in the superior vena cava during venovenous extracorporeal membrane oxygenation for severe pneumonia: A case report
Authors: Song Xiao-Qin , Jiang Yun-Long , Zou Xian-Bao , Chen Shi-Chao , Qu Ai-Jun , Guo Ling-Ling
Published: January 2024

BACKGROUND

Venovenous extracorporeal membrane oxygenation (V-V ECMO) has become an important treatment for severe pneumonia, but there are various complications during the treatment. This article describes a case with severe pneumonia successfully treated by V-V ECMO, but during treatment, the retrovenous catheter, which was supposed to be in the right internal vein, entered the superior vena cava directly in the mediastinum. The ECMO was safely withdrawn after multidisciplinary consultation. Our experience with this case is expected to provide a reference for colleagues who will encounter similar situations.

CASE SUMMARY

A 64-year-old man had severe pulmonary infection and respiratory failure. He was admitted to our hospital and was given ventilation support (fraction of inspired oxygen 100%). The respiratory failure was not improved and he was treated by V-V ECMO, during which the venous return catheter, which was supposed to be in the right internal vein, entered the superior vena cava directly in the mediastinum. There was a risk of massive mediastinal bleeding if the catheter was removed directly when the ECMO was withdrawn. Finally, the patient underwent vena cava angiography + balloon attachment + ECMO withdrawal in the operating room (prepared for conversion to thoracotomy for vascular exploration and repair at any time during surgery) after multidisciplinary consultation. ECMO was safely withdrawn, and the patient recovered and was discharged.

CONCLUSION

Patients may have different vascular conditions. Multidisciplinary cooperation can ensure patient safety. Our experience will provide a reference for similar cases.
Gestational diabetes mellitus combined with fulminant type 1 diabetes mellitus, four cases of double diabetes: A case report
Authors: Li Hui , Chai Yun , Guo Wei-Hong , Huang Yu-Meng , Zhang Xiao-Na , Feng Wen-Li , He Qing , Cui Jin , Liu Ming
Published: January 2024

BACKGROUND

Fulminant type 1 diabetes mellitus (FT1DM) that occurs during pregnancy or the perinatal period is known as pregnancy-related FT1DM (PF), always without history of abnormal glucose metabolism. Here, we present four patients who developed FT1DM during treatment but were first diagnosed with gestational diabetes mellitus (GDM).

CASE SUMMARY

The clinical data of four patients with GDM combined with FT1DM admitted to our hospital between July 2018 and April 2021 were collected, and the patients and their infants were followed up. All patients were diagnosed with GDM during the second trimester and were treated. The blood glucose level elevated suddenly during the third trimester and then were diagnosed with FT1DM. Two patients had an insulin allergy, and two had symptoms of upper respiratory tract infection before onset. One patient developed ketoacidosis, and three developed ketosis. Two patients had cesarean section deliveries, and two had vaginal deliveries. The growth and development of the infants were normal. C-peptide levels were lower than those at onset, suggesting progressive impairment of islet function. The frequencies of the DRB1 09:01, DQB1 03: 03, DQA1 03:02, DPA1 01:03, DPA1 02:02, DPB1 05:01, DRB4 01:03, G 01:01, and G 01:04 human leukocyte antigen (HLA)-G alleles were high in the present study.

CONCLUSION

In comparison with pregnancy-associated FT1DM (PF), patients with GDM combined with FT1DM had an older age of onset, higher body mass index, slower onset, fewer prodromal symptoms, and less acidosis. The pathogenesis may be due to various factors affecting the already fragile β-cells of GDM patients with genetically susceptible class II HLA genotypes. We speculate that GDM combined with FT1DM during pregnancy, referred to as “double diabetes,” is a subtype of PF with its own unique characteristics that should be investigated further.
Adenocarcinoma of sigmoid colon with metastasis to an ovarian mature teratoma: A case report
Authors: Wang Wei , Lin Chun-Chi , Liang Wen-Yi , Chang Shih-Ching , Jiang Jeng-Kai
Published: January 2024

BACKGROUND

Colorectal cancer ranks third in global cancer-related mortality, often due to metastases to liver and lungs. Ovarian metastases are less common, accounting for 3.6% to 7.4% of cases. In contrast, mature ovarian teratomas are frequently benign. Tumor-to-tumor metastasis is a rare phenomenon, with a limited number of documented cases. Three cases of mature ovarian teratomas metastasizing from different cancers have been reported. This report focuses on a case of tumor-to-tumor metastasis from sigmoid colon adenocarcinoma to a mature ovarian teratoma.

CASE SUMMARY

A 41-year-old Taiwanese woman with no known systemic diseases presented with lower back pain, which led to imaging revealing malignant lesions in the spine, pelvis, liver, and multiple lung metastases. She was diagnosed with sigmoid colon adenocarcinoma with metastases to the liver, lung, bone, and a left ovarian teratoma. Treatment involved radiotherapy and chemotherapy, resulting in regression of the primary tumor and stable lung and liver lesions. Due to abdominal symptoms, she underwent exploratory surgery, unveiling a mature teratoma in the left ovary with signs of metastatic adenocarcinoma.

CONCLUSION

Consider resecting mature ovarian teratomas with concurrent colorectal adenocarcinoma to prevent tumor-to-tumor metastasis.
Reseña de: Jairo Baquero, Frank Muller, Markus Rauchecker y Ramiro Segura (editores). El posacuerdo en Colombia. Procesos situacionales. Temporalidad. Territorio y Materialidad. Bogotá, Universidad del Rosario, 2022
Authors: Charry Carlos A.
Published: January 2024

Reseña de libro
Feminismo: Debates actuales, ambigüedades, conflictos y olvidos
Authors: Fernández Lamelas Eva
Published: January 2024

El propósito de este artículo es cartografiar algunos de los debates actuales en el movimiento feminista del Estado español. En concreto, veremos que en las actuales orientaciones feministas existe un feminismo liberal que además de la posición de clase, refleja el etnocentrismo de mujeres blancas que aspiran a compartir los privilegios de los hombres blancos, adultos, pero también existen las propuestas del feminismo decolonial, del feminismo del 99%, del feminismo interseccional o del feminismo queer. En el análisis se abordará también la cuestión sobre cómo la presencia masiva en la calle, durante las citas clave que se vienen produciendo desde 2018, no se traduce necesariamente en una mayor fortaleza organizativa
EL NOTICIARIO DEL NO-DO: UN BREVE ESTUDIO RADIOGRÁFICO
Authors: ROSICH ARGELICH RICARD
Published: January 2024

NO-DO
MUJERES ARTISTAS EN EL NO-DO POSTFRANQUISTA (1975-1981). UN ENFOQUE TRANSVERSAL DE GÉNERO SOBRE LA MIRADA DEL ESPECTADOR Y EL NARRADOR EXTRADIEGÉTICO
Authors: SÁNCHEZ GARCÍA SANDRA
Published: January 2024

El NO-DO (Noticiarios y Documentales) fue uno de los medios de control utilizados por el régimen franquista para la difusión de contenidos, noticias y reportajes afines a su doctrina. La mujer jugó un papel fundamental en cuanto a su difusión nos referimos, pues era a su vez el público mayoritario que visualizaba este tipo de contenidos. Por lo tanto, el enfoque del NO-DO estaba destinado a ofrecer una imagen sumisa y relegada al ámbito del hogar de esta, con un fin doctrinal amparado por el régimen. Tan fue así que, durante los años que este noticiario estuvo vigente, concretamente entre finales de 1942 y mediados de 1981, se difundieron numerosos reportajes sobre la Sección Femenina de Falange y sobre la mujer y sus oficios. En lo referente al arte y sus funciones, así como grandes nombres del panorama artístico y plástico, fueron divulgados a lo largo de los años con cierta asiduidad y recurrencia en el NO-DO. Sin embargo, estos reportajes, en su gran mayoría, contienen sólo nombres masculinos. Existe una pequeña porción de artistas mujeres que han sido objeto de entrevistas en el NO-DO. Bajo una perspectiva de género y analizando la mirada del espectador y al narrador extradiegético -a través de una metodología histórico-artística-, analizaremos las artistas femeninas que han sido incluidas en el NO-DO en la época postfranquista, así como las connotaciones y cómo son representadas en estas secciones del Noticiario-Documental.
COMPENDIO BIBLIOGRÁFICO ACERCA DEL NO-DO (1987-2023)
Authors: ROSICH ARGELICH RICARD , CRUSELLS VALETA MAGÍ
Published: January 2024

Bibliografía NO-DO
EL NO-DO ENTERO AL ALCANCE DE TODOS LOS ESPAÑOLES
Authors: CRUSELLS VALETA MAGÍ
Published: January 2024

Editorial vol. 33, núm 2 (2023)
Sentido de comunidad en latinoamericanos residentes en Málaga (España): Una propuesta de intervención basada en el fortalecimiento comunitario.
Authors: Millán-Franco Mario , Domínguez de la Rosa Laura , Hombrados-Mendieta Isabel , Gómez-Jacinto Luis
Published: January 2024

El objetivo principal de este estudio es indagar en la asociación de los bloques temáticos y repertorios interpretativos obtenidos a través de los análisis de dos investigaciones previas cuyo fin fue caracterizar el sentido de comunidad en latinoamericanos residentes en Málaga. El segundo objetivo de este artículo es establecer propuestas de intervención comunitaria eficaces para desarrollar el fortalecimiento comunitario del vecindario en donde residen las personas de origen latinoamericano. Esta investigación se constituye como un metaanálisis cualitativo. Concretamente, en los dos estudios previos se empleó un método cualitativo, específicamente el análisis temático y el análisis discursivo. La muestra inicial estaba compuesta por 30 participantes. La recogida de información se realizó a través de entrevistas en profundidad y semiestructuradas. Se ha comprobado la influencia recíproca entre el sentido de comunidad y la participación y, por tanto, con el fortalecimiento comunitario. De este modo, se propone el desarrollo de Presupuestos Participativos en las zonas donde residen las personas de origen latinoamericano entrevistadas. Y, en última instancia, la puesta en marcha de una radio y una revista comunitaria posibilitaría incidir en dos niveles complejos de abordar, el procesal y el simbólico, acometiendo principalmente las distintas dimensiones del sentido de comunidad, la participación y el fortalecimiento comunitario.
Entonación del español de Tonalá, Chiapas
Authors: Gómez Cortés Alejandra , Velásquez Upegui Eva Patricia
Published: January 2024

La descripción de la entonación en la costa mexicana es hasta ahora un área de estudio poco explorada; por tanto, su descripción representa una oportunidad para reconocer la diversidad en la variación geoprosódica de México. En este artículo se presentan los resultados del estudio de la entonación en los enunciados declarativos e interrogativos (absolutos y pronominales) en el español de Tonalá, ciudad perteneciente a la región istmo-costa del estado de Chiapas (México) y tiene como objetivo el registro de las diferencias y semejanzas entre la entonación de dicho municipio y la documentada en otras ciudades del país para reconocer la posible existencia de un español costeño mexicano. En este estudio se consideró como base teórica el modelo autosegmental (Pierrehumbert, 1980; Ladd, 1996; Hualde, 2003) y la notación Sp_ToBI (Hualde y Prieto, 2015).
Los resultados sugieren que no existen mayores diferencias entre el español hablado en las costas de Tonalá en comparación con otras variedades mexicanas hasta ahora descritas. Sin embargo, se reconocen particularidades entonativas en los enunciados interrogativos, lo que valida la propuesta de que los rasgos prosódicos característicos de cada variante dialectal del español se reflejan, principalmente, en este tipo de enunciados.
Dynamics of labor and capital in AI vs. non-AI industries: A two-industry model analysis
Authors: Huang Xu
Published: January 2024

There is an imbalance in the development of artificial intelligence between industries. Compared to non-AI enterprise, AI- enterprise will save labor, enhance innovation capabilities, and improve production efficiency. By constructing a two-industry model of AI and non-AI enterprise, this paper finds that with the development of artificial intelligence in the same industry, the AI enterprise will occupy a dominant position, attracting labor and capital from the non-AI enterprise into the AI enterprise. In different industries, the development of artificial intelligence improves the production efficiency of the enterprise. However, due to the price effect, non-AI enterprise benefits more. Labor and capital flow from AI enterprise to non-AI enterprise. In order to promote the improvement of production efficiency in the whole society, the government can tax non-AI enterprise and subsidize them to AI enterprise. Taxation promotes the degree of automation and the improvement of production efficiency, but it has only a short-term effect on the development of AI. At the same time, taxation inhibits the development of non-AI enterprise, and there is a high risk of unemployment. When both industries use artificial intelligence for production, the labor share and the capital share of the two industries will tend to the same value. The convergence of technology measures is conducive to increasing labor income share and reducing income inequality, but it is not conducive to innovation.
Reinterpreting the pretty picture: A speculative aesthetics of microscopy
Authors: Ketelsen Lucie
Published: January 2024

This article looks at the positioning of the aesthetic in microscopy to understand how it can be both side-lined and deployed. It considers the boundary between the pictorial and the notational in current microscopy practice and speculates on a space of mutual relation. Microscopy’s dual threads of capture for data analysis and capture for publication reveal complicated relationships and conflicted stances, reflective of a broader iconoclastic tendency in microscopy where the image as enacted perception is erased while the notation generated and carried by these images is preserved. This article seeks to suggest a space in which phenomena are situated, materially embedded and emergent through imaging practices. I ground my position on experimental imaging of bacterial iridescence to consider the entanglement of microscopy’s living image with its processes of making-seen. Microscopy is instrumental in supporting descriptive-explanatory claims on biological life yet is also implicated in the generation of novel, hybrid phenomena and sensibilities. Exploring both tendencies exposes a microscopy of permeable membranes and suggests alternative orientations through microscopy practice and its images.