bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of the IDH1/2 gene mutations in tumor samples with low abundance of the mutant allele
Authors: Varachev V. O. , Guskov D. A. , Susova O. Y. , Shekhtman A. P. , Rogozhin D. V. , Surzhikov S. A. , Chudinov A. V. , Zasedatelev A. S. , Nasedkina T. V.
Published: December 2024

Identification of driver mutations in tumors is an extremely important task in oncology for the choice of treatment strategy and assessment of therapy efficacy. In many cases, especially in disease monitoring, there is a need to detect a small number of copies of the mutant allele against the background of excessive content of wild-type DNA. In this work we investigated the possibilities of highly sensitive detection of mutations in IDH1 and IDH2 genes at suppression of wild-type DNA amplification using oligomers of “locked” nucleic acid (LNA) with subsequent hybridization of fluorescently labeled polymerase chain reaction (PCR) product on a biological microchip (biochip). The limit of detection of mutant DNA is 0.1% in the wild-type DNA background. The effectiveness of this approach is demonstrated by analyzing 26 samples of chondroid tumors and glial brain tumors with low representation of the mutant allele, previously undetected mutations R132C, R132L and R132H were identified in three cases.
Multigroup model of calculating the low-energy electron transport in weakly ionized gases
Authors: Bochkov E. I.
Published: December 2024

Proceeding from the Boltzmann kinetic equation for electrons, the system of multigroup equations for the zero and first moments of the distribution function of low-energy electrons is derived within the Lorentz approximation. The system includes the balance equations for concentration and flux density of electrons and is intended for numerical simulation of the transport and kinetics of electrons in the energy range from zero to several tens of electron volt where the angular distribution of electrons is weakly anisotropic.Results of the numerical calculations of electron transport in helium in homogeneous and inhomogeneous electric fields according to the developed multigroup model are compared with results obtained by the Monte Carlo method.
Physicochemical activation of distilled water by a jet of microwave plasma argon in an atmosphere of water vapor
Authors: Sergeichev K. F. , Lukina N. A.
Published: December 2024

A method for activating water by plasma of an electrodeless torch discharge in a microwave electromagnetic field in argon in an environment of water vapor, at atmospheric pressure, to obtain a pure solution of hydrogen peroxide H2O2 without impurities in distilled water is proposed. It is shown that the main mechanism for the formation of atomic hydrogen H• and hydroxyl HO• radicals in the water decomposition is photolysis under the influence of excimer vacuum ultraviolet radiation of argon plasma. Hydrated electrons can be an additional source of radicals in liquid water when the plasma torch comes into contact with the water surface. Today plasma technologies are widely used to produce activated water containing hydrogen peroxide, to solve environmental problems, to increase productivity in agriculture, and for medical use.
Aspect, tense, modal force, and the effects of event variables in Romanian “a accepta + că / să”
Authors: Hegedus Csongor
Published: December 2024

In this paper, I analyse the predicate a accepta “to accept” followed and sometimes preceded (in previous events) by either the realis type conjunction că “that” or by the irrealis să “SJV marker”. I try to answer questions like: (1) what are the boundaries between the two main modal forces, thus what happens when they appear simultaneously (or individually), (2) how these conjunctions might change the aspectual verification, donating, sharing or keeping (in terms of Roberts 2019), in CCs (Complex Clauses) with event variables (Davidson 1967), (3) how the Vendlerian (1967) classification might affect the general perception of the mentioned predicate when it is combined with other dependent / non-dependent events. The aim of the paper is to check the temporal, aspectual, and modal boundaries in the mentioned construction, so it is based on syntactical and cognitive notions. The analysis includes the relative compatibility of că “that” with [I’ and w’] – which is usually associated with non-finite forms, and the accomplishment compatibility of să “SJV marker” – which is more prominent with CCs involving că “that” (with perfective events). The polarity-based negation is also part of the paper (in the examined structure), leading to negation as operator vs. stancetaking. The temporal and aspectual gaps are also key-points of the paper.
Game-based learning and gamification in Cuban English teacher trainees
Authors: Luis Carr Roberto
Published: December 2024

This study investigates the potential of game-based learning and gamification to enhance English Language Teaching in resource-limited contexts, focusing specifically on Cuban teacher trainees’ engagement, motivation, and vocabulary learning. Based on interviews with Cuban trainees. These activities incorporate educational games, simulations, and interactive tasks aimed at vocabulary learning, using mechanics such as awarding points for contextual vocabulary use. Using a mixed-methods approach with surveys and interviews, findings reveal that Cuban teachers also had favorable perceptions of gamification, recognizing its ability to create more interactive classrooms despite resource challenges. The study suggests gamification could transform ELT in Cuba.
Neurodidactics and vocabulary acquisition in Cuban teacher trainees: Emerging trends
Authors: Romero Enriquez Damarys
Published: December 2024

This study deals with the emerging field of neurodidactics and its implications for vocabulary acquisition. More precisely, the article presents a bibliometric analysis of a dataset comprising 32 papers from 24 sources, spanning the period from 2011 to 2023. The data were acquired from Web of Science and analyzed using the R-Bibliometrix package. The study identifies research trends, emerging and interdisciplinary areas, as well as citation factors, providing also a brief overview of the current state of vocabulary acquisition in Cuban language teaching in general, and in teacher training in particular. It aims to offer a global perspective on neurodidactics and an overview of its impact on vocabulary learning in the Cuban higher education system. Additionally, it identifies research gaps and suggests avenues for future studies and educational innovations.
Neurodidactic approaches in teaching Romanian language to pupils from underprivileged backgrounds. A case study based on the pupils from Garcini
Authors: Mada S. , Botiz A.-C.
Published: December 2024

This study follows up two projects regarding teaching Romanian language at academic level and at gymnasium level. The authors propose a neurodidactic approach to remedial teaching and learning of Romanian language to gymnasium pupils from disadvantaged areas. Such an approach responds to the needs and motivation of the pupils and to (at least) the minimum requirements of the national curriculum. The authors argue that introducing brain-friendly lessons and evaluation techniques throughout the gymnasium years could enhance pupils’ results in the Romanian language and literature national examination at the end of the learning cycle.
When Romance languages meet English – A (socio)linguistic study of the linguistic interferences
Authors: Bodoc Alice
Published: December 2024

The continuous process of globalization, the advancement of technology, and the sociolinguistic context are just three of the most important factors that influence the language practices of the Italian, Spanish, French, and Romanian speakers. Therefore, the aim of the present paper is to explore the nature and expanse of English influence on these linguistic varieties. From a methodological point of view, the study combines qualitative and quantitative research methods, including linguistic and comparative analyses, in order to investigate the impact of English, as well as the implications of the interferences on language use and communication. In particular, the analysis will focus on the “communication accommodation theory” that “explores why and how people modify their communication to fit situational, social, cultural, and relational contexts” (Giles, Taylor, and Bourhis 1973, 177). Ultimately, the entire article reinforces the concept of language as a living entity, having a dynamic nature and a great power in a globalized world.
PENGELOLAAN KEUANGAN DANA DESA DI KECAMATAN TAROGONG KALER
Authors: Dewi Nunik Lestari , Handayani Rini , Jovita Gabriella Alodia
Published: December 2024

Kinerja desa saat ini didukung oleh kebijakan pemerintah terkait dengan pengalihan dana desa yang bertujuan untuk memperkuat kualitas desentralisasi fiskal. Berbagai output infrastruktur yang dihasilkan dari dana desa sangat bermanfaat bagi kelangsungan hidup masyarakat desa. Artikel ini akan membahas tentang pengelolaan keuangan dana desa melalui kegiatan perencanaan, pelaksanaan, penatausahaan, pelaporan, dan pertanggungjawaban. Studi kasus di Kecamatan Tarogong Kaler Kabupaten Garut. Penelitian deskriptif dilakukan dengan alat bantu kuesioner. Hasil penelitian menunjukkan bahwa desa-desa di Kecamatan Tarogong Kaler Kabupaten Garut telah melaksanakan pengelolaan keuangan dana desa sesuai dengan Permendagri Nomor 20 Tahun 2018 dan telah memenuhi prinsip partisipasi, akuntabilitas, dan transparansi.
Penerapan Model Pembelajaran Inquiri Terbimbing dalam Meningkatkan Kemampuan Graphing Skills Siswa SMA pada Materi Pencemaran Lingkungan
Authors: SAPUTRA INDRA
Published: December 2024

Penelitian ini bertujuan untuk menganalisis peningkatan kemampuan graphing skills siswa SMAmelalui penerapan model pembelajaran inquiri terbimbing pada materi pencemaran lingkungan. Metodepenelitian yang digunakan adalah Quasi Experiment dengan desain The Matching-Only Pretest-PosttestControl Group Design yang dilaksanakan di salah satu SMA negeri di kota Bandung, Jawa Barat, kelas Xtahun pelajaran 2018/2019. Instrumen penelitian yang digunakan adalah pretes dan postes kemampuangraphing skills dalam bentuk soal uraian, lembar observasi keterlaksanaan pembelajaran, serta angkettanggapan guru dan siswa. Hasil analisis penelitian menunjukkan bahwa pembelajaran dengan modelinquiri terbimbing berjalan sesuai dengan tahapan Rencana Pelaksanaan Pembelajaran, terdapatpeningkatan kemampuan graphing skills siswa dengan model pembelajaran inquiri terbimbing ditunjukkanoleh rata-rata N-Gain yang diperoleh yaitu 0,60. Indikator-indikator pada setiap kemampuan graphingskills yang meliputi kemampuan interpretasi, representasi, dan analisis data, peserta didik mengalamipeningkatan dalam kategori sedang, dengan rata-rata nilai N-Gain 0,52. Hasil penelitian juga menunjukkanbahwa respon siswa terhadap pembelajaran dengan model inquiri terbimbing pada umumnya baik danpositif
Efektivitas Strategi Pembelajaran Everyone Is a Teacher Here Terhadap Hasil Belajar Siswa (Pada Konsep Ekosistem
Authors: Ai Wina Nuraina  , De Budi Irwan Taofik
Published: December 2024

Penelitian ini bertujuan untuk mengetahui efektivitas strategi Everyone Is a Teacher Here terhadap konsep ekosistem. Desain penelitian ini One Group Pretest Posttest Design. Metode penelitian pre-experimental, populasinya siswa kelas VII SMP Negeri 1 Bayongbong sebanyak 9 kelas, sampelnya yaitu kelas VII-B, tekhnik pengambilan sampel secara purposive sampling. Tekhnik pengolahan data menggunakan kriteria Nurgana, KKM sekolah penelitian, Gain Ternormalisasi dan Rata-rata tingkat Penguasaan/ RTP . Berdasarkan hasil post-test yang didapat 28 siswa memperoleh nilai 75 dengan persentase 77,78% melampaui 75% maka penerapan strategi Everyone Is a Teacher Here pada konsep ekosistem adalah efektif. Gain Ternormalisasi menunjukkan hasil yang baik, dengan persentase 52,78% pada kategori baik, 41,67% pada kategori sedang dan 5,55% pada kategori rendah, rata-rata Gain=0,637 berada pada kategori sedang. RTP menunjukkan hasil yang sangat baik dengan tercapainya 84,72% berada pada kriteria tinggi.
Analisis Miskonsepsi Siswa Pada Sub Konsep Sistem Sirkulasi Dengan Menggunakan Instrumen Four-Tier Diagnostic Test
Authors: NURFADILLAH ALDA
Published: December 2024

Tujuan penelitian untuk mendeskripsikan profil miskonsepsi siswa pada sub konsep sistem sirkulasi denganmenggunakan instrumen four-tier diagnostic test. Penelitian ini termasuk penelitian deskriptif kuantitatif.Sampel yang digunakan dalam penelitian ini yaitu siswa yang dipilih secara purposive sampling dari siswakelas XI MIPA SMA Negeri 26 Garut tahun ajaran 2019/2020. Metode pengambilan data berupa tes dannon tes, tes dalam penelitian ini yaitu tes tulis four-tier diagnostic test yang dikembangkan oleh QisthiFariyani, dk., sedangkan teknik non tes berupa dokumentasi, wawancara, dan angket. Four-tier diagnostictest adalah tes yang terdiri atas 4 tingkatan, yaitu soal dengan pilihan jawaban, pilihan tingkat keyakinanjawaban, pilihan alasan dan pilihan tingkat keyakinan alasan. Hasil interpretasi four-tier diagnostic testmenunjukkan terdapat 25 profil miskonsepsi siswa ditemukan pada materi Sistem Sirkulasi, persentasesiswa yang mengalami miskonsepsi pada konsep sistem sirkulasi sebesar 68,06% dengan kategori tinggi.Sub materi apa yang persentase miskonsepsinya terbesar pada materi sistem sirkulasi dengan menggunakaninstrumen four-tier diagnostic test ditemukan pada sub konsep sistem limfa sebesar 75%. Faktor-faktoryang menyebabkan miskonsepsi yaitu pemikiran asosiatif, instuisi siswa yang salah, buku teks, pemahamansiswa dari guru, dan internet.
Pengaruh Ekstrak Jahe Merah (Zingiber officinale var. rubrum) terhadap Daya Hambat Pertumbuhan Bakteri Staphylococcus aureus
Authors: Bonita Yunpayani  , Leni Sri Mulyani
Published: December 2024

Jahe merah memiliki kandungan minyak atsiri dan oleoresin yang dapat menghambat pertumbuhanbakteri Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui daya hambat ekstrak jahe merah(Zingiber officinale var. rubrum) terhadap pertumbuhan bakteri Staphylococcus aureus dan manakahkonsentrasi ekstrak jahe merah (Zingiber officinale var. rubrum) yang paling efektif terhadap daya hambatpertumbuhan bakteri Staphylococcus aureus. Penelitian ini menggunakan metode Rancangan AcakLengkap (RAL) dengan menggunakan 6 perlakuan. Penelitian ini menggunakan 24 sampel dengan ujihipotesis yang digunakan yaitu Uji Kruskal-wallis dan Uji Schefee. Parameter yang diukur dalam penelitianini adalah diameter zona hambat. Hasil penelitian ini menunjukan jika ekstrak jahe merah (Zingiberofficinale var. rubrum) dapat menghambat pertumbuhan bakteri Staphylococcus aureus. Konsentrasiekstrak jahe merah (Zingiber officinale var. rubrum) yang paling efektif terhadapt daya hambat bakteristaphylococcus aureus adalah 100% dengan daya hambat rata-rata 24mm.
Pengembangan Buku Saku IPA Berbasis Learning Cycle Pada Materi Sistem Ekskresi Manusia
Authors: Syarifah Sheila Azmi  , Ahmad Shafwan S.Pulungan
Published: December 2024

Penelitian ini bertujuan untuk menghasilkan produk Buku Saku IPA berbasis learning cycle pada materi sistem ekskresi manusia yang layak diterapkan dalam proses pembelajaran IPA di sekolah. Jenis penelitian ini merupakan penelitian pengembangan atau Research and Development (R&D) menggunakan model ADDIE. Subjek dalam penelitian ini adalah siswa kelas VIII A dan VIII B di SMP Negeri 40 Medan. Instrumen yang digunakan dalam penelitian ini terdiri dari angket validasi ahli materi, ahli media dan ahli pembelajaran, angket penilaian respon guru, angket respon peserta didik dan instrumen tes untuk mengetahui hasil belajar peserta didik terhadap buku saku IPA berbasis learning cycle. Teknik analisis data yang digunakan dalam penelitian ini adalah persentase. Dari hasil analisis data diperoleh validasi ahli materi sebesar 91% dengan kategori “Sangat Layak”, ahli media 80,20% dengan kategori “Layak”, dan ahli pembelajaran 96,64% dengan kategori “Sangat Layak”. Penilaian Respon guru IPA sebesar 100% dengan kategori “Sangat Layak”. Respon peserta didik setelah menggunakan buku saku sebesar 97% termasuk kategori “Baik”. Sedangkan pada hasil tes peserta didik melakukan pretes dan postest sehingga didapatkan nilai N-Gain sebesar 0,71 termasuk kategori tinggi dan efektif.
Pengaruh Limbah Cair Tahu dengan Konsentrasi yang Berbeda terhadap Pertumbuhan Tanaman Mentimun (Cucumis Sativus L.)
Authors: Eki Sutarman  , Lida Amalia  , Diah Ika Putri
Published: December 2024

Penelitian ini bertujuan untuk mengetahui pengaruh berbagai konsentrasi limbah cair produksi tahu terhadap pertumbuhan tanaman mentimun (Cucumis sativus L.)Metode yang digunakan adalah metode eksperimen dengan rancangan acak kelompok (RAK). Jumlah perlakuan terdiri atas lima macam dengan lima pengulangan. Perlakuan A = 0%, perlakuan B = 5%, perlakuan C = 10%, perlakuan D = 15%, perlakuan E = 20%. Jumlah sampel sebanyak 75 bibit tanaman mentimun (Cucumis sativus L.). parameter yang diukur yaitu tinggi tanaman, jumlah daun, dan jumlah sulur tanaman mentimun (Cucumis sativus L.). Hasil penelitian menunjukkan bahwa limbah cair produksi tahu memberikan pengaruh terhadap tanaman mentimun (Cucumis sativus L.) yang mencakup tinggi tanaman, jumlah daun, dan jumlah sulur. Konsentrasi yang paling efektif untuk pertumbuhan tinggi tanaman mentimun yaitu konsentrasi D (15%) dengan rata-rata 75,04 cm. Sedangkan jumlah daun dan jumlah sulur yang paling efektif yaitu dengan konsentrasi B (5%) dengan rata-rata 21,6 helai dan 14,8.
Pengaruh Media Pembelajaran Flashcard terhadap Hasil Belajar Siswa pada Materi Bioteknologi di Kelas X SMAN 16 Garut
Authors: Indra Dodo Saputra  , Siti Nurul Khodijah  , Asep Rohayat  , Sri Mulyaningsih  , Lida Amalia
Published: December 2024

Permasalahan utama dalam penelitian ini adalah kepasifan siswa selama proses pembelajaran jugadisebabkan oleh pemilihan media pembelajaran yang tidak tepat sehingga menyebabkan rendahnya hasilbelajar siswa. Berdasarkan permasalahan tersebut, tujuan penelitian dirumuskan untuk mengetahuibagaimana pengaruh media pembelajaran flashcard terhadap hasil belajar siswa terhadap materibioteknologi di kelas X SMAN 16 GARUT. Metode yang digunakan dalam penelitian ini adalah QuasiExperiment dengan desain eksperimen yang digunakan yaitu non-equivalent pretest-posttest controlgroup design. Populasi dalam penelitian ini adalah seluruh siswa kelas X SMAN 16 GARUT, sedangkansampel adalah kelas X J kelas aplikasi media flashcard pada materi bioteknologi dan kelas X L yangmenerapkan media gambar hitam putih pada materi bioteknologi sebagai media pembanding. Instrumen yangdiuji adalah tes objektif (pilihan ganda) dengan total 30 pertanyaan. Berdasarkan tes akhir (posttest)menggunakan tes t ( (Tes Sampel Mandiri) hasil belajar siswa diketahui Sig.(2-tailed) adalah 0,002 < 0,05, makaHa diterima dan Ho ditolak. Sehingga terdapat pengaruh yang signifikan terhadap penggunaan mediaflashcard terhadap hasil belajar materi bioteknologi di kelas X SMAN 16 Garut. Penggunaan flashcard nmediadapat lebih meningkatkan hasil belajar siswa dilihat dari rata-rata skor posttest pada kelas eksperimenmenggunakan media Flashcard yaitu 77,72 dibandingkan rata-rata skor posttest pada kelas kontrolmenggunakan media gambar hitam putih yaitu 55,94.
Therapeutic potential of resveratrol, a polyphenol in the prevention of liver injury induced by diethylnitrosamine (DEN) through the regulation of inflammation and oxidative stress
Authors: RAHMANI ARSHAD HUSAIN , Alharbi Hajed Obaid A , Khan Amjad Ali , Babiker Ali Yousif , Rizvi M. Moshahid Alam
Published: December 2024

Background: Resveratrol (RES) is an essential polyphenolic compound found in various foods, including vegetables, fruits, and chocolate. Its antioxidants and anti-inflammatory potential have attracted significant interest in the management of pathogenesis, including the treatment of hepatocellular carcinoma.
Objectives: This study was designed to measure RES hepatoprotective potential against Diethylnitrosamine (DEN)-induced liver injury.
Methods: The hepatoprotective potential of RES (20 mg/kg b.w) was evaluated by measuring the liver function enzymes, oxidative stress, and inflammation against DEN (200 mg/kg i.p)-induced liver injury. The liver tissue architecture and fibrosis were determined using hematoxylin and eosin, Masson trichrome, and Sirius Red staining. Moreover, the expression pattern of Cyclooxygense-2 (Cox-2) protein was evaluated by immunohistochemistry staining.
Results: Seven weeks of RES treatment after exposure to toxic DEN led to a significant reduction in liver function enzymes (AST, ALT, and ALP) and lipid peroxidation compared to rats treated by DEN only. Further, results showed that RES treatment reduced the pro-inflammatory cytokines (TNF-α, CRP, IL-1β, and IL-6) and increased the antioxidant enzymeFunctional Foods in Health and Disease 2024; 14(12): 898-920 FFHD Page 899 of 920 (Catalase, SOD, GST, and GPx) levels compared to rats treated by DEN only. The DEN-induced group of rats showed various liver tissue alterations, increased fibrosis, and high Cox-2 protein expression. However, the group treated with RES showed hepatoprotective potential with reduced liver tissue alterations and fibrosis. Moreover, RES treatment decreased the Cox-2 protein expression compared to rats treated by DEN only, suggesting its anti-inflammatory potential.
Conclusion: This study revealed that RES treatment reduced DEN-induced hepatic injury and liver cancer by protecting liver cells by reducing oxidative stress, inflammation, and liver function enzymes. Therefore, the results indicate that RES could be a possible therapeutic approach for liver diseases, including drug and alcohol-related problems.
Keywords: Resveratrol, Hepatoprotective, Oxidative stress, Inflammation and cancer, Alcohol-related problems, Fibrosis
Impact evaluation of a mass media public education campaign on clinic service provision for minors diagnosed with ADHD/ADD: Audit survey of 100 index families
Authors: Baldwin Steve
Published: December 2024

One hundred UK families of children/teenagers diagnosed with ADHD were included in an audit survey of service provision. The impact was examined of a mass media public education campaign about ADHD and the use of methylphenidate. Short, medium and long‐term effects of MPH prescription to young children and teenagers was also investigated. It was observed that parents agreed to MPH prescription, when there were few other non‐drug treatments available. The clinical and health risks of MPH ingestion by minors were examined, as well as problems of drug regulation in schools.
Dirac’s Large Number Hypothesis: An Ongoing Quest for Correlations Between the Infinitesimal and the Infinite
Authors: Jiang Jonathan , Liu Ethan , Chen Yanbei
Published: December 2024

Dirac's Large Number Hypothesis (LNH), proposed in 1937, has captivated the scientific community with its exploration of profound correlations between cosmic and atomic scales. This hypothesis delves into the intricate interplay between the infinitesimally small and the vastly large, offering potential insights into the fundamental nature of the universe. As we continue to uncover the mysteries of the cosmos, the LNH oscillates on the precipice of scientific acceptance—neither fully validated nor entirely dismissed. In this review paper, we embark on a comprehensive journey through Dirac's LNH, shedding light on its theoretical underpinnings, its implications for universe models, and its resonance with the Anthropic Principle. We delve into the possibilities of variable gravitational constants and continuous mass creation, inviting further exploration into the intricacies of our cosmic symphony. By embracing the ongoing quest for understanding, we endeavor to unravel the profound harmonies that connect the infinitesimal with the infinite, contributing to the symphony of knowledge in theoretical physics and cosmology.
Social and Spatial Drivers of the Multitiered Structure of Zebra Finch Social Networks
Authors: Zhang Yixuan , Jiang Xinyi , Aplin Lucy M. , Wang Daiping , Farine Damien R.
Published: December 2024

Social network structure plays a key role in shaping processes in animal populations. These networks often show distinct patterns in humans and other large mammals, with relationship strengths organized into different tiers. Here, we used continuous, fine-scale tracking of four large captive colonies of zebra finches (_Taeniopygia guttata_), revealing that zebra finches consistently have 1-2 closest contacts, 6-7 close contacts, and 22-24 strong contacts. The identities of these contacts remain stable across days, with strong contacts maintained by spatial affinity while closest and close contacts are maintained by social choice. These results suggest that zebra finches egocentric networks and social structure are made up of consistent, differentiated relationships forming a multitiered social structure.

The similarities in patterns to other species suggest that fundamental principles, such as limitations in time and the ability to move through social space, could drive common structural properties in animal social networks.
Pioneering Digital Ventures: Investigating Proactive Personality, Education, and Opportunity in Malaysian Higher Education
Authors:   Universiti Sains Malaysia, Kee Daisy Mui Hung , Khor Yen Jou ,   Universiti Sains Malaysia, Khor Jie Ning ,   Universiti Sains Malaysia, Han Jia Yue ,   Universiti Sains Malaysia, Jiang Xin Lan ,   Universiti Sains Malaysia, Singh Ayushi ,   IMS Engineering College
Published: December 2024

Digital entrepreneurship has become increasingly important in the context of Industry 4.0. This study explores the connections between digital entrepreneurial intention, proactive personality, entrepreneurial education, and entrepreneurial opportunity among Malaysian public university students. Additionally, it examines the mediating roles of attitudes, subjective norms, and PBC, guided by the TPB. A quantitative research design was employed, collecting data from 250 students, which was then analyzed using SPSS to test the proposed model. The findings reveal that entrepreneurial education and PBC are significant predictors of students’ digital entrepreneurial intention. Moreover, proactive personality, entrepreneurship education, and entrepreneurial opportunity indirectly influence digital entrepreneurial intention via PBC. These results contribute to a more nuanced understanding of the factors driving digital entrepreneurial intention and highlight the importance of fostering educational environments that support entrepreneurship. The study provides valuable insights for educators and policymakers to develop strategies that enhance digital entrepreneurial capacities among students, promoting innovation and self-employment opportunities
The Role of Professional Training in Developing Leadership Skills Among Information Technology Sector Employees
Authors:   Universiti Sains Malaysia, Anwar Aizza , Chaudhary Rashmi ,   IMS Engineering College, Aziz Nur Anis Najihah Binti ,   Universiti Sains Malaysia, Azhar Nur Anis Athirah Binti ,   Universiti Sains Malaysia, Elias Nur Anisah Sakinah Binti Mohamed ,   Universiti Sains Malaysia, Azhar Nur Arisya Binti ,   Universiti Sains Malaysia, Mittal Pallavi ,   IMS Engineering College, Kee Daisy Mui Hung ,   Universiti Sains Malaysia
Published: December 2024

As technology advances, the professional world is becoming increasingly competitive. Achieving career success and meeting professional goals now requires both new and seasoned employees to continuously develop their skills and expand their knowledge. This necessity highlights the importance for businesses in the IT sector to expose their employees to professional training programs that enhance leadership skills, ultimately benefiting the organization. The main aim of this study is to examine the impact of professional training on leadership skills development among IT sector employees, focusing on the challenges and benefits identified through a qualitative approach. Data was collected via a survey questionnaire, with responses from 200 participants in Malaysia and India. The findings reveal the impact of professional training for IT employees, particularly regarding the role of training activities in fostering leadership development. This study offers insights and guidance for employees on the advantages and obstacles of pursuing professional training, leading to enhanced leadership capabilities
The Determinants of Earnings Management in Manufacturing Companies Listed on the Indonesia Stock Exchange
Authors:   Mahasaraswati University, Bhegawati Desak Ayu Sriary , Rustiarini Ni Wayan ,   Mahasaraswati University, Widyantari Ida Ayu Putu Surya ,   Mahasaraswati University, Ariandini Ida Ayu Made ,   Mahasaraswati University, Dewi Ni Kadek Listya ,   Mahasaraswati University
Published: December 2024

Profit control is an important issue in corporate governance arising from the conflict of interest between owners and managers. Weak supervision can facilitate earnings management practices by managers. This study aims to empirically examine the effect of firm size, institutional ownership, independent commissioners, the board of directors, and the audit committee on earnings management. Using the purposive sampling method, 42 manufacturing companies listed on the Indonesia Stock Exchange for the period 2021-2023 were selected as samples. Data analysis includes classical assumption test, model goodness test, and multiple linear regression analysis. The results showed that independent commissioners, board of directors, and institutional ownership had no significant effect on earnings management. In contrast, firm size and audit committee characteristics have a negative effect on earnings management. The findings conclude that corporate governance mechanisms have diverse roles in controlling earnings management practices. This study suggests strengthening the role of the audit committee and increasing transparency in large companies to mitigate earnings management. The implications of this study emphasize the importance of evaluating and improving corporate governance mechanisms to improve the quality of financial reporting
The Influence of Social Class, Lifestyle, and Personality on Buying Decisions at the Car Showroom in Denpasar
Authors:   University of Mahasaraswati Denpasar, Antara I Kadek Dwi Widi , Savitri Ni Made Hary Diah ,   University of Mahasaraswati Denpasar, Putra I Wayan Anggi Pramana ,   University of Mahasaraswati Denpasar, Cahyana Gusti Ayu Kadek ,   University of Mahasaraswati Denpasar, Sasmita Ni Kadek Windi ,   University of Mahasaraswati Denpasar, Mitariani Ni Wayan Eka ,   University of Mahasaraswati Denpasar, Hendrawan I Gede Yudhi ,   University of Mahasaraswati Denpasar
Published: December 2024

Along with the increasing number of car users which shows the development of lifestyles among people in Indonesia, many consumers who have owned a car before wish to sell their old car or exchange it for a new car, thus generating used cars that are still worth selling and providing opportunities for used car showroom business actors. The purpose of this study was to analyze the influence of social class, lifestyle, and personality on purchasing decisions for used Toyota cars at the Dharma Mahendra Mobilindo showroom in Denpasar. The data analysis technique uses multiple linear regression using the SPSS for Windows version 25 program. The results of the analysis in this study show (1) Social class has a positive and significant effect on purchasing decisions for used Toyota cars at DMM showrooms, (2) Lifestyle has a positive and significant effect on purchasing decisions for used Toyota cars at DMM showrooms, (3) Personality has a positive and significant effect on purchasing decisions for used Toyota cars at DMM showrooms. These findings suggest that businesses should focus on segmenting their marketing efforts based on social class, lifestyle preferences, and personality traits to better appeal to their target audience and optimize sales strategies.
Periodontitis Borne Risk Factors & Oral Health: A Pilot Study
Authors: Rawat Preeti , Bhardwaj Amit , Dave Aparna , Chandra Nimai Chand
Published: December 2024

This study targets to earmark the risk factors that gets emerged in saliva and serum in the pathogenicity of periodontitis. ELISA based kits were used to estimate the risk components (TNF-a, IL-10 and IgA) in saliva and serum following company directed protocols. Colorimetry or spectrophotometry was used for the other estimations. Patients critically suffered from periodontitis, having pocket depth beyond 4mm, were found mildly affected with systemic hyperglycemia and dyslipidemia besides salivary hyperglycemia. The pro-inflammatory cytokine TNF-a  was found exorbitantly high in the saliva of the periodontitis affected subjects. No significant change of the anti-inflammatory cytokine (IL-10) was observed in the saliva except, a marginal increase in serum as compared to the control group. A remarkably low IgA level was found in both serum and saliva of the patients suffered from periodontitis. Blood groups of the subjects in this study didn’t show any correlation to the periodontitis infection. Females were found more vulnerable to periodontitis infection than the male counterparts. Lacking appropriate dental care could be the primary reason of making rooms for the settlement of microbes around teeth periphery causing periodontal pathogenicity.
Keywords: Periodontitis, TNF-α, IL-10, IgA, Oral infection
«Römische Elegie»: Collaboration between Joseph Brodsky and Antoni Tàpies
Authors:   Institute of World History of the Russian Academy of Sciencei, Kuzina Nataliya
Published: December 2024

This article explores the collaboration between Joseph Brod-sky and Antoni Tàpies in creating the artist’s book (livre d’artiste) Roman Elegies (1993), published by Erker Galerie in St. Gallen, Switzerland. Despite the cultural significance of both figures, their joint work remains largely underexplored. The study focuses on an interdisciplinary approach that com-bines literary analysis of Brodsky’s poetry with an examina-tion of visual elements in Tàpies’ lithographs. Common themes are highlighted in the works of both artists. The au-thor investigates how Brodsky’s handwritten texts interlace with Tàpies’ graphic symbols and materials, including cross-es and handprints. Additionally, the technical aspects of the book’s creation, such as lithographic processes and materials, are analyzed to reveal philosophical and cultural allusions. The article also addresses the political context and personal experiences of the artists. Supplementary research and interviews with participants contribute to filling gaps in knowledge about this collaboration between two outstanding cultural figures.
Mexican progressivism. Balance and perspectives of the 4T
Authors:   Center for Research in Social Sciences and Regional Studies of the Autonomous University of the State of Morelos, Zendejas Maximo Julio Diego
Published: December 2024

The government of Andrés Manuel López Obrador (AMLO) configured the Mexican version of progressivism. The great support for his administration and the resounding electoral victory of Claudia Sheinbaum to continue the self-proclaimed Fourth Transformation (4T) raise questions about the scope, limitations and perspectives of this process. For this reason, this work analyzes the socioeconomic and political proposal that it tried to implement and its results. First, the historical origin of the project and the objectives of its government pro-gram are synthesized. Next, some data and quantitative indi-cators are presented to assess the achievements obtained and thirdly, we refer to the contradictions and limits of his strate-gy to seek to overcome neoliberalism and its consequences in the reorganization of state power since it gave continuity to militarization. Finally, and based on this balance, we reflect on the direction that the second administration of the 4T can follow.
The debate between communists and trotskyists on the 1930 Revolution in Brazil
Authors:   Federal Institute of Paraná, Pansardi Marcos Vinícius
Published: December 2024

This article sets out to analyze the debate that took place in the 1920s and 1930s between communists and Trotskyists about the meaning of the 1930 Revolution in Brazil. It would be possible to analyze the various political shades of opinion that interpreted the 1930 Revolution by the way in which they sought to include the people in the political game. Seen with horror, as in the conservative view, or seen with admiration, as in the progressive view, the people became, from that mo-ment on, the real watershed with whom those who ventured into the political arena would have to come to terms. The Trotskyists saw popular participation as stimulated by the elites in their struggle for power. On the other hand, the PCB view tended to see popular participation as fundamental, ei-ther because it produced a reactionary backlash, or because it realized that the masses were really on the boil and were fol-lowing their own paths, which forced sectors of the ruling class to alter their previously stipulated course. The conclu-sion of the debate among Brazilian Marxists shows that both communists and Trotskyists considered the 1930 Revolution to be a watershed, seen as the movement that put an end to an era and opened the doors to "modernity" in Brazil, with its main cause and effect being the irruption of the popular masses as a fundamental political agent.
An Analysis of Popular Culture Novels Can Function as a Site of Memory: A Case Study of The Great Gatsby
Authors: Gao Hua
Published: December 2024

Memory scholar and historian Nora clarifies that “memory is a perpetually actual phenomena, a bond tying us to the eternal present; history is a representation of the past”. Historical memory and literary creations have a tight relationship. Literary works, as places of memory, can reflect and shape historical memory, while historical and cultural memory serve as a basis for literary work creation. “Memory, then, is not straightforward: it is not just a recalling of the past. It is much more complicated than this; and it involves us in political existence, while also giving us a sense of identity and giving us a sense of difference”. Hirsch pointed out that this type of memory that transmits events they did not experience in the collective memory to the “generation after” through stories, images, and behaviours is called post memory. This essay will analyse how Fitzgerald's literary work “The Great Gatsby “shaped the memories of the time.
Research on Cloud Computing Network Security Framework Based on Machine Learning
Authors: Li Yan , Ma Genjuan
Published: December 2024

This paper studies and proposes a machine learning-based network security framework for cloud computing, which aims to deal with diverse security threats in cloud environments. By designing data collection, feature extraction, model training and dynamic protection mechanisms, the framework can detect and respond to intrusions, malware and abnormal behaviors in the cloud platform in real time. The results show that machine learning has significant advantages in improving detection accuracy and response speed, and the framework has adaptive learning ability and can dynamically adjust protection strategies.
FINDINGS FROM AN EXPEDITION INVESTIGATING EPIGRAPHIC AND ARCHITECTURAL MONUMENTS IN THE VILLAGE OF SHAKHUVA (LAKSKY REGION, REPUBLIC OF DAGESTAN)
Authors: Kurbanov Akhmed J. , Kayaev Ilyas A.
Published: December 2024

The article focuses on the examination of epigraphic and architectural monuments in the village of Shakhuva, located in the Laksky region of the Republic of Dagestan. It presents, for the first time, epigraphic materials dating back to the 18th–19th centuries, shedding light on specific aspects of the social and political history of the region’s development. These materials include tombstones bearing the emblem of the Shamkhal, indicative of the presence of authoritative figures within the society, as well as the graves of village residents who perished during the 1877 uprising in Dagestan. Notably, among these graves is that of Shagmilav, a prominent leader of the Tsudahar battle and a key imam serving under Shamil during the Caucasian War. The analysis extends to architectural features, notably the partially preserved Kyulla-mizit mosque, which served additional functions and was once situated outside the settlement. This mosque facilitated complete ritual ablution (ghusl) for men. Also examined is a structure positioned atop a steep rocky ridge above the village, resembling a tower externally and offering panoramic views of the Kazikumukhskoye Koisu River valley. The article presents arguments regarding the origins of the toponym “Shahuva,” suggesting its early form as “Shaku” or “Shahu.”
GENEALOGY AND SILSILA OF SUFI SHEIKHS OF THE KHALWATIYYA ORDER IN THE LEZGIN VILLAGE OF KHLYUT
Authors: Zakariyaev Zamir Sh
Published: December 2024

The paper reveals the results of studying the genealogy and the chain of spiritual succession of Sufi sheikhs who lived in the 18th–19th centuries in the mountainous Lezgi village of Khlyut, South Dagestan. A Sufi monastery, known as “Tekke”, was located there. The founder of the monastery was Sheikh Muhammad-‘Ali, who is believed to be of Yemen origin. We present the text and annotated translation of an early list of a valuable historical source in Arabic for the first time. The list has been found to be compiled approximately in the middle of the 18th century, which makes it the earliest surviving document of this kind in Dagestan. It includes both the spiritual genealogy (silsila) and the lineage (nasab) of the Khlyut sheikhs. The author managed to almost completely restore the content of the main text of the document, which became possible due to the presence of two handwritten lists. We conclude that the main text of the late list, with the exception of a small interpolated insert, was carried over from the early list. Both lists end with small late additions with information about two branches of the sheikhs’ descendants. An analysis of the genealogy of Khlyut spiritual figures shows that they were descendants of Sufi sheikhs who lived in northern Shirvan. Silsila contains the names of the most famous medieval Sufis of the Muslim world and goes back to the Yemeni Tabi‘in Uwais al-Qarani, and through him to ‘Ali b. Abi Talib. The mention in the silsila of famous Shirvan sheikhs of the 15th century of the Khalwatiyya order, as well as their successors, who lived in the mountains of southern Dagestan, leaves no doubt that the Khlyut sheikhs also belonged to this Sufi brotherhood. It has been established that the vigorous activity of Khalwatiyya in South Dagestan was not limited only to the Late Middle Ages, but continued later. The Arabic-language inscriptions of the Tekke complex, on the territory of which the burial places of Sufis, the remains of residential buildings and premises for Sufi practices are located, have also been studied.
ANCIENT FORTRESSES OF THE SEA COAST OF THE WESTERN CAUCASUS AND DAGESTAN – TO THE QUESTION OF LOCALIZATION, CORRELATION AND PRESERVATION
Authors: Kizilov Andrey S.
Published: December 2024

The article notes that over the past decade, as a result of active research in historical, military and local history archives, as well as archaeological exploration, the list of existing ancient structures on the coast of the foothills of the Black and Caspian Seas has expanded significantly. On the example of densely urbanized areas of coastal settlements, the general trends in the formation of archaeological gaps are traced, which gave information gaps in the system of historical reconstruction of the eras of antiquity and the Middle Ages. It is noted that in the studied areas, the ancient coastal centers of urbanization suffered significant losses due to climatic changes in sea levels relative to zero. Also, the described sites were actively affected by numerous uncontrolled developments of newly formed settlements at the end of the 19th and throughout the 20th centuries. Due to the imperfection in the system of legislation in the field of preservation of the archaeological historical and cultural heritage, not only the archeological monuments themselves were lost, but also the documents reflecting the fact of their existence. Sub-legislative acts are imperfect in this matter to this day. When comparing the events that took place simultaneously on the coasts of the Black and Caspian Seas in different epochs, one can see the localization and fate of the studied ancient centers of intersection of cultures and ethnic groups common to the regions. It is emphasized that if there is an appropriate combination of monitoring of archaeological sites and legislative support for its effectiveness, a number of monuments of historical and cultural heritage can be identified and introduced into scientific circulation.
Pengaruh Pengungkapan Corporate Social Responsibility dan Kualitas Audit terhadap Biaya Utang
Authors: Yanni Yanni , Serly Serly , Tang Sukiantono
Published: December 2024

This research aims to analyze the impact of Corporate Social Responsibility disclosure and audit quality on debt costs. We also use company size, return on assets, and leverage as control variables in this study. The research method employs financial data from companies published on the Indonesia Stock Exchange as the sample to be tested using panel regression. The software used includes SPSS and Eviews10. The results of this study indicate that Corporate Social Responsibility disclosure does not have a significant impact on debt costs. Meanwhile, audit quality significantly and negatively affects debt costs. The control variable results show that return on assets significantly and negatively affects debt costs, while company size and leverage do not have a significant impact on debt costs.
Peran Green Accounting dalam Mewujudkan Prinsip Pembangunan Berkelanjutan
Authors: Mubarokah Annisa Kharirotul , Setyaningsih Nina Dwi
Published: December 2024

Environmental accounting is an important part of improving a company's environmental performance. Green accounting is a concept developed in Europe in 1970. This concept is used to identify, prioritize, and incorporate environmental costs in business decision making. By using green accounting, companies can reduce environmental problems and increase the effectiveness of environmental management. Despite this, the use of green accounting is still limited in developing countries. This research uses a qualitative descriptive data collection method which includes observation, interviews, documentation and triangulation. The findings show that Bakpia Maharani MSMEs face challenges related to waste management and financial reporting, because they do not allocate costs for prevention and detection, but instead focus on waste processing. This research aims to determine the implementation of green accounting in Bakpia Maharani MSMEs and identify related challenges.
Pengaruh Pengetahuan Pajak, Tarif Pajak, Dan Sanksi Pajak Terhadap Kepatuhan Wajib Pajak Orang Pribadi Bagi Pelaku Usaha Online
Authors: Basiroh Alfi , Sari Ika
Published: December 2024

This study aims to gather empirical evidence on the influence of tax knowledge, tax rates,  and  tax sanctions on the tax compliance of individual online entrepreneurs in Jabodetabek. This quantitative research employed simple random sampling as the sampling technique, resulting in 97 respondents. Primary data was collected through direct distribution of questionnaires. Data analysis was conducted using Structural Equation Modeling (SEM) based on Partial Least Square (PLS) using SmartPLS 4.0. The findings revealed that tax knowledge and tax sanctions variables do not significantly influence taxpayer compliance, while the tax rate variable significantly impacts taxpayer compliance.