bluuebunny/crossref_metadata_2025 huggingface dataset:
Intersectoral collaboration for people-centred mental health care in Timor-Leste: a mixed-methods study using qualitative and social network analysis
Authors: Hall Teresa , Kakuma Ritsuko , Palmer Lisa , Minas Harry , Martins João , Armstrong Greg
Published: November 2019

Background

Intersectoral collaboration is fundamental to the provision of people-centred mental health care, yet there is a dearth of research about how this strategy operates within mental health systems in low- and middle-income countries. This is problematic given the known attitudinal, structural and resource barriers to intersectoral collaboration in high-income country mental health systems. This study was conducted to investigate intersectoral collaboration for people-centred mental health care in Timor-Leste, a South-East Asian country in the process of strengthening its mental health system.

Methods

This study employed a mixed-methods convergent design. Qualitative data elicited from in-depth interviews with 85 key stakeholders and document review were complemented with quantitative social network analysis to assess understandings of, the strength and structure of intersectoral collaboration in the Timorese mental health system.

Results

There was consensus among stakeholder groups that intersectoral collaboration for mental health is important in Timor-Leste. Despite resource restrictions discussed by participants, interview data and social network analysis revealed evidence of information and resource sharing among organisations working within the health and social (disability and violence support) sectors in Timor-Leste (network density = 0.55 and 0.30 for information and resource sharing, respectively). Contrary to the assumption that mental health services and system strengthening are led by the Ministry of Health, the mixed-methods data sources identified a split in stewardship for mental health between subnetworks in the health and social sectors (network degree centralisation = 0.28 and 0.47 for information and resource sharing, respectively).

Conclusions

Overall, the findings suggest that there may be opportunities for intersectoral collaborations in mental health systems in LMICs which do not exist in settings with more formalised mental health systems such as HICs. Holistic understandings of health and wellbeing, and a commitment to working together in the face of resource restrictions suggest that intersectoral collaboration can be employed to achieve people-centred mental health care in Timor-Leste.
The use of lytic polysaccharide monooxygenases in anaerobic digestion of lignocellulosic materials
Authors: Costa Thales H. F. , Eijsink Vincent G. H. , Horn Svein Jarle
Published: November 2019

Background

The recent discovery that LPMOs can work under anaerobic conditions when supplied with low amounts H2O2opens the possibility of using LPMOs as enzyme aids in biogas reactors to increase methane yields from lignocellulosic materials. We have explored this possibility by studying anaerobic digestion of various lignocellulosic materials: Avicel, milled spruce and birch wood, and a lignin-rich hydrolysis residue from steam-exploded birch. The digestions were added LPMOs and various cellulolytic enzyme cocktails and were carried out with or without addition of H2O2.

Results

In several cases, enzyme addition had a beneficial effect on methane production, which was partly due to components present in the enzyme preparations. It was possible to detect LPMO activity during the initial phases of the anaerobic digestions of Avicel, and in some cases LPMO activity could be correlated with improved methane production from lignocellulosic materials. However, a positive effect on methane production was only seen when LPMOs were added together with cellulases, and never upon addition of LPMOs only. Generally, the experimental outcomes showed substrate-dependent variations in process efficiency and the importance of LPMOs and added H2O2. These differences could relate to variations in the type and content of lignin, which again will affect the activity of the LPMO, the fate of the added H2O2and the generation of potentially damaging reactive-oxygen species. The observed effects showed that the interplay between cellulases and LPMOs is important for the overall efficiency of the process.

Conclusion

This study shows that it may be possible to harness the power of LPMOs in anaerobic digestion processes and improve biogas production, but also highlight the complexity of the reaction systems at hand. One complicating factor was that the enzymes themselves and other organic components in the enzyme preparations acted as substrates for biogas production, meaning that good control reactions were essential to detect effects caused by enzyme activity. As also observed during regular aerobic enzymatic digestion of lignocellulosic biomass, the type and contents of lignin in the substrates likely plays a major role in determining the impact of LPMOs and of cellulolytic enzymes in general. More work is needed to unravel the interplay between LPMOs, O2, H2O2, and the multitude of redox-active components found in anaerobic bioreactors degrading lignocellulosic substrates.
Idiopathic granulomatous hypophysitis presenting with galactorrhea, headache, and nausea in a woman: a case report and review of the literature
Authors: Sharifi Guive , Mohajeri-Tehrani Mohammad Reza , Navabakhsh Behrouz , Larijani Bagher , Valeh Touraj
Published: November 2019

Background

Inflammation of the pituitary gland can occur in a variety of primary or secondary disorders. Idiopathic granulomatous hypophysitis is a rare inflammatory disease of the pituitary gland that can closely mimic a pituitary adenoma clinicoradiologically. Most authorities agree on minimally invasive transsphenoidal surgery as the mainstay in diagnosis and treatment of this disorder. There is still some controversy regarding pure medical management of idiopathic granulomatous hypophysitis in the literature.

Case presentation

A 47-year-old Iranian woman of Azeri ethnicity with a history of benign breast cysts with a chief complaint of galactorrhea presented to our endocrinology clinic. Her past medical history was negative for any menstrual irregularities, hirsutism, visual complaints, diplopia, polyuria and polydipsia or seizures. She was taking 100 mcg of levothyroxine daily. Her familial history and physical examination were unremarkable. Her initial laboratory work-up revealed hyperprolactinemia (82.4 ng/mL) with otherwise normal pituitary axes. Brain magnetic resonance imaging showed a pituitary macroadenoma for which she was treated with 0.5 mg of cabergoline weekly. Although her serum prolactin level dropped to 1.7 ng/mL and her galactorrhea was resolved, she continued to complain of headaches and nausea. Repeated imaging showed no decrease in size of the macroadenoma. Therefore, she underwent transsphenoidal surgery of the macroadenoma which was reported as chronic granulomatous hypophysitis by expert pathologists. Tuberculosis, sarcoidosis, Wegener’s granulomatosis, Langerhans cell histiocytosis, and syphilis were ruled out by appropriate tests and she was diagnosed as having idiopathic granulomatous hypophysitis. Fortunately, her condition was not complicated by hypopituitarism and she was symptom free 9 months after transsphenoidal surgery.

Conclusions

Idiopathic granulomatous hypophysitis, a rare inflammatory disease of the pituitary gland, is a diagnosis of exclusion for which both medical and surgical management are reported in the literature. We present a case of idiopathic granulomatous hypophysitis who was symptom free with no complications of hypopituitarism following its transsphenoidal resection after 9 months of follow-up.
Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease
Authors: Henderson Michael X. , Sengupta Medha , Trojanowski John Q. , Lee Virginia M. Y.
Published: November 2019

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iPD) patients, the neuropathology of LRRK2 PD is less clearly defined. Lewy bodies (LBs) composed of α-synuclein are a major feature of iPD, but are not present in all LRRK2 PD cases. There is some evidence that tau may act as a neuropathological substrate in LB-negative LRRK2 PD, but this has not been examined systematically. In the current study, we examined α-synuclein, tau, and amyloid β (Aβ) pathologies in 12 LRRK2 mutation carriers. We find that α-synuclein pathology is present in 63.6% of LRRK2 mutation carriers, but tau pathology can be found in 100% of carriers and is abundant in 91% of carriers. We further use an antibody which selectively binds Alzheimer’s disease (AD)-type tau and use quantitative analysis of tau pathology to demonstrate that AD tau is the prominent type of tau present in LRRK2 mutation carriers. Abundant Aβ pathology can also be found in LRRK2 mutation carriers and is consistent with comorbid AD pathology. Finally, we assessed the association of neuropathology with clinical features in LRRK2 mutation carriers and idiopathic individuals and find that LRRK2 PD shares clinical and pathological features of idiopathic PD. The prevalence of AD-type tau pathology in LRRK2 PD is an important consideration for understanding PD pathogenesis and refining clinical trial inclusion and progression criterion.
Detailed descriptions of the lower-middle Triassic and Permian formations using cores and gamma-rays from the EPS-1 exploration geothermal borehole (Soultz-sous-Forêts, Upper Rhine Graben, France)
Authors: Aichholzer C. , Duringer Ph. , Genter A.
Published: November 2019

In the 1950s, a petroleum well in Soultz-sous-Forêts (no 4589; Upper Rhine Graben, France) reached the Lettenkohle (Triassic) at 830 m depth. During the exploration phase at Soultz-sous-Forêts, the first enhanced geothermal system pilot project in the world, the well was core-deepened up to 2227 m into the granitic basement (then renamed EPS-1). The objectives of this deeper well were (i) to explore the granitic fractured reservoir and (ii) provide a precise geological characterization of the Soultz-sous-Forêts horst. This paper presents the first complete core analysis of the sedimentary formations observed in the EPS-1 cores (from the middle Muschelkalk to the Permian) in conjunction with the gamma-ray log description and field works. The detailed descriptions of the geological formations encountered in the well are presented with photo boards displaying the most characteristic facies of each formation, since the wells are rarely cored, especially in the Muschelkalk. This study also aims to describe the gamma-ray log to provide a strong baseline for future geothermal well exploration in this area (or old well reinterpretations). At this time, it is the only available reference for the complete section: Muschelkalk to Permian sedimentary formations.
Characterizing popularity dynamics of hot topics using micro-blogs spatio-temporal data
Authors: Wu Lianren , Li Jinjie , Qi Jiayin
Published: November 2019

In this paper, a quantitative temporal and spatial analysis of the dynamics of hot topics popularity in Micro-blogging system was provided. Firstly, the popularity time series of 1167 hot topics were counted and calculated by Excel. Secondly, based on MATLAB software,the popularity time series were clustered into six clusters by K-spectral centroid (K-SC) clustering algorithm. Thirdly, we analyzed temporal patterns and spatial patterns of popularity dynamics of topics by statistical methods. The results show that temporal popularity of micro-blogging topics is rapidly dying, and the distribution of popularity is subject to the power law form. In addition, most of the Micro-blogging topics are global topic. Our results can provide a literature reference for studying the influence of online hot topics and the evolution of public opinion.
Risk factor analysis of the decrease in gait speed among Japanese older outpatients with polypharmacy
Authors: Deguchi Masataka , Nishida Keigo , Enokiya Tomoyuki , Ooi Kazuya
Published: November 2019

Background

Both polypharmacy and frailty are critical issues faced by the elderly. The decrease in gait speed is an index of frailty, and it is generally associated with falls and fractures, which are risk factors requiring the need for support or long-term patient care. In this study, we assess the risk factors responsible for the decrease in gait speed in older outpatients with polypharmacy.

Methods

Thirty-one persons (13 men, 18 women) aged 65 years or above and regularly taking 5 or more internal medications participated in this study.

Results

Propensity score-adjusted multivariate logistic analysis showed that only number of medications was associated with the risk of decreasing gait speed (odds ratio: 16.00, 95% confidence interval:1.72–149.00, p value = 0.0149). A negative correlation was found between the number of medications and gait speed. In addition, the gait speed of the calcium channel blocker medication group was significantly slower than that of the non-medication group.

Conclusion

These results suggest that not only the number of medications but also the prescription contents is a risk factor for decrease in gait speed and may serve as indexes to identify patients at high risk of requiring support or long-term care.
A Literature Review of Painful Hashimoto Thyroiditis: 70 Published Cases in the Past 70 Years
Authors: Peng Carol Chiung-Hui , Huai-En Chang Rachel , Pennant Majorie , Huang Huei-Kai , Munir Kashif M
Published: November 2019

Painful Hashimoto thyroiditis (pHT) is a rare diagnosis, and optimal treatment remains unclear. To better characterize pHT, PubMed, Embase, Scopus, and Web of Science indexes were searched for case reports or case series reporting pHT, published between 1951 and February 2019. Seventy cases reported in 24 publications were identified. Female predominance (91.4%) and a median age of 39.00 years (interquartile range, 32.50-49.75 years) were observed. Among reported cases, 50.8% had known thyroid disease (including Hashimoto thyroiditis, Graves disease, and seronegative goiters), 83.3% had positive antithyroid peroxidase antibodies, and 71.2% had antithyroglobulin antibodies. Most cases did not have preceding upper respiratory tract symptoms or leukocytosis. Ultrasound features were consistent with Hashimoto thyroiditis. Thyroid function at initial presentation was hypothyroid (35.9%), euthyroid (28.1%), or thyrotoxic (35.9%). Cases evolved into hypothyroidism (55.3%) and euthyroidism (44.7%), whereas none became hyperthyroid after medical treatment. Thyroid size usually decreased after medical treatment. Most cases were empirically treated as subacute thyroiditis with corticosteroids, levothyroxine, or nonsteroidal anti-inflammatory drugs. However, no therapy provided sustained pain resolution. In subgroup analysis, low-dose oral prednisone (<25 mg/d) and intrathyroidal corticosteroid injection showed more favorable outcomes. Total thyroidectomy yielded 100% sustained pain resolution. Diagnosis of pHT is based on clinical evidence of Hashimoto thyroiditis and recurrent thyroid pain after medical treatment. The reference standard of diagnosis is pathology. Total thyroidectomy or intrathyroidal glucocorticoid injection should be considered if low-dose oral prednisone fails to achieve pain control.
Teaching Laboratory Renovation
Authors: Al-Zuhairi Ali Jassim , Al-Dahhan Wedad H. , Hussein Falah H. , Rodda Kabrena E. , Yousif Emad
Published: November 2019

The improvement of students’ awareness of concepts in science and its uses, practical scientific abilities and considerate of how science and scientists effort in laboratory experiences have been considered key aspects of education in science for over 100 years. Facility requirements for the necessary level of safety and security combined with specific requirements relevant to the course to be conducted dictate the fundamental strategy of a specific lab, and the strategy procedure need to address both. This manuscript is the second in a series of five case studies describing laboratory incidents, accidents, and laboratory improvements. We summarize the process used to guide a major renovation of the chemistry instructional laboratory services at Al-Nahrain University and discuss lessons learned from the project
Use of Nitrogenous Fertilizers and its Impact on Water Quality with Special Reference to Agricultural Development
Authors: Parashar V.K
Published: November 2019

Water is an essential commodity of life on the earth. It plays a very important role in agricultural development. Agricultural activity impacts the water quality through the movement of chemical fertilizers and other poisonous materials from the agricultural fields to deep aquifers through surface runoff and deep percolation. The important source and cause of agricultural pollution are irrigational return flows and use of nitrogenous fertilizers in which nitrate is the basic component. High concentrations of Nitrate in natural water may cause methemoglobinemia, and have been cited as a risk factor in developing gastric and intestinal cancer. One of the most important negative effect of intensive use of nitrogenous fertilizer use is water eutrophication. Nitrates in the irrigational water serves as a nutrient to plants and crops. The agricultural water quality guide lines proposed by Ayers and Westcot (1994) mentions that the nitrate concentration ranges from 22.5 to 135 mg/l causes slight to moderate restriction and above 135 mg/l nitrate concentration causes severe restriction on crops for irrigational use. Due to the impact of fertilizers on human and environment, it is quite necessary to reduce the nitrate concentrations in natural waters to protected levels.
Caracterização dos cuidadores informais de idosos dependentes quanto aos aspectos demográficos e de saúde
Authors: Alves Beatriz Santos , Oliveira Alessandra Souza de Oliveira , Santana Elaine dos Santos , Chaves Renato Novaes , Marinho Maykon dos Santos , Reis Luciana Araújo dos
Published: November 2019

Introdução: A saúde do cuidador tem sido variável importante nos estudos com cuidadores de idosos dependentes, sendo evidenciados baixos índices de bem-estar e saúde. O cuidador informal realiza sua função na maioria das vezes de forma solitária, sem auxílio de outros familiares ou orientação de profissionais da saúde. Objetivo: Caracterizar os cuidadores informais de idosos dependentes quanto aos aspectos socio- demográficos e de saúde. Métodos: Pesquisa do tipo analítico transversal com abordagem quantitativa de tratamento e análise de dados. Realizada com 42 cuidadores informais de idosos dependentes funcionais no domicílio cadastrados em Unidades de Saúde da Família (USF) de três bairros de um município do interior da Bahia. Para coleta dos dados, foi utilizado questionário com dados sociodemográficos e de saúde. Os dados coletados foram organizados em uma planilha Excel® 2015 e em seguida transportados e analisados no programa Statistical Pack age for the Social Science SPSS® versão 21.0, sendo então realizada análise estatística descritiva. Resultados: Observou-se maior frequência de cuidadores de idosos dependentes do sexo feminino (90,5%), com a idade entre 41 a 50 anos (28,6%) e 51 a 60 anos (21,4%). Casados (as) (35,7%) e solteiros (as) 33,3%. Com escolaridade prevalente o ensino fundamental incompleto (47,6%) e ensino médio completo 23,8%. Quanto aos dados de avaliação das condições de saúde, verificou-se que a maioria dos cuidadores de idosos dependentes referiu problemas de saúde (59,5%), sendo mais citadas HAS (16,7%), doenças osteomusculares (14,3%) e HAS associado a doenças osteomusculares (9,5%). Conclusão: Os cuidadores informais no domicílio possuem perfil de vulnerabilidade social e de saúde, carecendo de medidas protetivas nos aspectos biopsicossociais.
Ser idoso no Norte do Brasil: uma análise a partir de usuários da Atenção Básica na periferia de Belém, Pará (Guamá)
Authors: Lima Bonfim Neto Luiz , Ferreira Silva Marcello José , Ramos Protásio Matheus , Viégas Brandão Fernando Mateus , Barros dos Santos Igor , Souza Dacier Lobato Carla Mércia
Published: November 2019

O objetivo desse estudo é identificar e caracterizar o perfil da população idosa atendida na atenção primária no bairro do Guamá no município de Belém, Pará: O trabalho foi realizado em indivíduos com mais de 60 anos de idade atendidos na Unidade Municipal do Guamá. Como ferramentas, foram aplicados questionários com dados sócios demográficos e de saúde; além da análise do estado cognitivo, emocional e risco de queda. Participaram da pesquisa 116 idosos, dos quais houve um predomínio de mulheres. Encontraram-se prevalências de 29,31% de depressão geriátrica e 80,17% de déficit cognitivo na população estudada, além de averiguar que 74,14% da amostra pesquisada apresentava alto rico de queda. A maior participação de mulheres no estudo é reflexo do processo de feminização do envelhecimento. Os valores encontrados acerca de depressão geriátrica e risco de queda foram compatíveis com outros diversos outros estudos, no entanto, houve uma discrepância com a maioria dos estudos quanto a prevalência de déficit cognitiva nessa população, algo que pode interferir diretamente na qualidade de vida do idoso.
Thyroid diseases detection rate in screenings of the population of the Kherson region
Authors: Yaroshenko V. I. , Golunov A. I.
Published: November 2019

In many regions of the world, regardless of the presence of iodine endemic, a steady increase in thyroid pathology has been recorded over the past three decades. Given the unfavorable environmental situation that is typical for most countries today, one can think that this trend will continue and problems of the state of the thyroid gland will take place among the most relevant and significant in modern clinical medicine.

A natural consequence of this is the growing interest of scientists and practitioners of endocrinologists in the issues of early diagnosis and monitoring, the etiology and epidemiology of thyroid diseases.

In this study, we assessed the state of the thyroid gland with the aim of epidemiological analysis of the frequency of various forms of goiter in 5423 people living in 18 districts of Kherson region.
Effects of plasmapheresis and immunocorrecting therapy on T-immunity of pa¬tients with autoimmune thyroiditis
Authors: Kalinin A. P. , Rafibekov D. S. , Potemkina Ye. Ye. , Pesheva N. V. , Shabalin V. N.
Published: November 2019

T-cellular immunity was studied in 104 patients with autoimmune thyroiditis to assess the function of the thyroid and treatment method. A reliable reduction of the activity of T-lymphocyte receptor system, lymphopoiesis activation, and their relationship with the thyroid status were revealed. Plasmapheresis as monotherapy was used in 22 patients. It brought about a short-term positive effect, this necessitating search for other methods of' immunorehabilitation. In 82 patients it was supplemented with immunocorrecting therapy (thymalin) and in 49 with hypothyrosis with substitution therapy (L-thyroxine, thyroidin). Combined therapy helped attain a stable clinical and immunological effect. Subpopulation composition of T-lymphocytes recovered, their functional activity normalized (follow-up period 1 year).
Secretion of bioactive and immunoreactive luteinizing hormone in patients with the polycystic ovaries syndrome
Authors: Goncharov N. P. , Dobracheva A. D. , Yarovaya I. S.
Published: November 2019

Basal secretion of immunoreactive and bioactive LH was measured in 24 patients with polycystic ovaries, secretion during LH-RF test in 18 patients. Basal LH level was assessed from in vitro testosterone secretion by murine Leydigs cells. The content of basal LH and basal LH to FSH ratio in patients with the polycystic ovaries syndrome was markedly increased vs. the norm. Three types of gonadotroph responses were observed in the patients in response to LH-RF, these responses differing by increment rate, time course of secretion, and ratio of secreted basal and immunoreactive LH. Gonadotroph response was found related to ovarian morphology and clinical manifestations of the disease. Administration of LH-RF to patients with polycystic ovaries and tecomatosis changed the ratio of secreted basal and immunoreactive LH by reducing basal LH level. In young girls and women aged under 20 the increment of basal and immunoreactive LH noticeably surpassed its values in older patients with longer disease duration.
Lessicografia e critica del testo:
Authors: Viel Riccardo
Published: November 2019

Attraverso una serie di tre esempî lessicali tratti dal corpus lirico del trovatore Giraut de Borneil, attestato nella seconda metà del XII secolo, si mostrerà come il modulo lessicale del database TrobVers sia in grado di aiutare il filologo nelle operazioni di sintesi e di valo- rizzazione della varia lectio dei manoscritti. Tali casi esemplari aiuteranno a riflettere circa il rapporto tra l’applicazione dei nuovi strumenti informatici a tradizioni testuali ecdotica- mente complesse e il metodo filologico, cercando di dimostrare che l’interfaccia digitale può aiutare nel difficile compito di coniugare la restitutio textus in termini neo-lachmanniani con la valorizzazione dei rapporti orizzontali e le redazioni lessicalmente significative delle differenti famiglie di manoscritti.

Some lexical examples from Giraut de Borneil’s lyric corpus (2nd half of the twelfth century) will show how textual scholarship may benefit from the database TrobVers, especially in locating and assessing the manuscript variants. Some cases in point will help shed new light on the relationship between the application of humanities computing to complex instances of textual transmission and broad methodological issues in textual scholarship. The essay argues that the digital interface may help bridge the gap between the neo-Lachmannian recensio and the necessary consideration of contamination and other forms of lexical inno- vation in the various groups of MSS.
Digital Editing and Linguistic Analysis:
Authors: Ventura Simone
Published: November 2019

Attraverso una serie di tre esempî lessicali tratti dal corpus lirico del trovatore Giraut de Borneil, attestato nella seconda metà del XII secolo, si mostrerà come il modulo lessicale del database TrobVers sia in grado di aiutare il filologo nelle operazioni di sintesi e di valo- rizzazione della varia lectio dei manoscritti. Tali casi esemplari aiuteranno a riflettere circa il rapporto tra l’applicazione dei nuovi strumenti informatici a tradizioni testuali ecdotica- mente complesse e il metodo filologico, cercando di dimostrare che l’interfaccia digitale può aiutare nel difficile compito di coniugare la restitutio textus in termini neo-lachmanniani con la valorizzazione dei rapporti orizzontali e le redazioni lessicalmente significative delle differenti famiglie di manoscritti.

Some lexical examples from Giraut de Borneil’s lyric corpus (2nd half of the twelfth century) will show how textual scholarship may benefit from the database TrobVers, especially in locating and assessing the manuscript variants. Some cases in point will help shed new light on the relationship between the application of humanities computing to complex instances of textual transmission and broad methodological issues in textual scholarship. The essay argues that the digital interface may help bridge the gap between the neo-Lachmannian recensio and the necessary consideration of contamination and other forms of lexical inno- vation in the various groups of MSS.
A Digital Edition between Stylometry and OCR:
Authors: Rebora Simone
Published: November 2019

This article presents the digital edition of Robert Musil’s work (Klagenfurter Ausgabe) and its role in a digital humanities project aimed at reconstructing Musil’s activity in the WWI journal Tiroler Soldaten-Zeitung. First, the article reviews the ways in which the compu- tational methods of stylometry are applied to attribute the anonymous texts published in the Klagenfurter Ausgabe. Second, it explores how optical character recognition (OCR) soft- ware is employed to expand the corpus. At the core of this methodology two machine learn- ing algorithms are trained and revised using the transcriptions of the Klagenfurter Ausgabe, to reach an accuracy of about 99.9% in the digitization of the Tiroler Soldaten-Zeitung texts. The work of this project offers not only the possibility of expanding stylometric analysis to the whole journal, but also of improving the transcriptions of the Klagenfurter Ausgabe.
Torquato Tasso’s Rime d’amore:
Authors: Perotti Diego
Published: November 2019

This essay examines the editorial tradition of Torquato Tasso’s Rime d’amore (love lyrics). Beginning with a general overview of the manuscript and printed traditions, the various stages in which the textual history of the edition has been divided by the Edizione Nazionale delle opere di Torquato Tasso (National Edition of Torquato Tasso’s Literary Works) will be analyzed, with special attention devoted to issues of authorial revision and structural re- arrangement. After clarifying some crucial points concerning Tasso’s final intention, espe- cially by means of his own letters from the periods in question, an alternative solution to the critical edition of Tasso’s Rime will be proposed.
Assessing the Micro-Deval Test for Compacted Dense-Graded Asphalt
Authors: Bazuhair Rabeea W. , Easterling Jonathan , Cox Ben C. , Howard Isaac L.
Published: November 2019

In recent years, the asphalt industry has been increasingly evaluating mixture testing for a variety of purposes. This article assesses the Micro-Deval (MD) test for its ability to evaluate compacted dense-graded asphalt mixtures. Historically, the MD test has been used to evaluate durability characteristics of loose aggregates, so this investigation deviates from the equipment’s intended purpose. MD testing was performed in traditional manners (i.e., submerged in water), as well as absent water. The investigation benchmarked MD testing against Cantabro mass loss and the Illinois Flexibility Index Test with an emphasis on use of the protocols during mixture production. Four evaluation criteria were used for assessment (level of rationality of test results, equipment cost, noise during testing, and time to achieve test results). Results of this investigation were that the MD testing protocol was not optimally suited for assessing compacted dense-graded asphalt. Wet MD tests (traditional test manner) were highly variable and provided no appealing test outputs. Operationally, the MD test was one of the noisier tests evaluated; it required an intermediate amount of time to conduct a test but had the lowest equipment cost. With all factors considered, the other tests considered are believed to be more promising than the MD for assessing dense-graded asphalt.
Stress Concentration Factors for ASTM E8/E8M-16a Standard Round Specimens for Tension Testing
Authors: Kardak A. A. , Sinclair G. B.
Published: November 2019

Occasionally, round specimens for tension testing that comply with ASTM standards fail in one of the transition regions between gage and grip sections. This occurs because of the stress concentration present in transition regions. When this happens, it is possible to seek stress relief by increasing fillet radii in these regions. The objective of this note is to quantify the relief afforded by increasing radii. The approach adopted to this end is finite element analysis that is carefully verified. Stress concentration factors are thus accurately determined to three figures for all of the various types of standard round specimens in ASTM E8/E8M-16a, Standard Test Methods for Tension Testing of Metallic Materials.
Dynamic Recrystallization in Titanium Alloys: A Comprehensive Review
Authors: Chatterjee Ritam , Narayana Murty S. V. S. , Alankar Alankar
Published: November 2019

This article is an attempt at highlighting recent advances made for understanding and modeling the phenomenon of dynamic recrystallization (DRX) prevalent in titanium alloys. Research work in recent years has focused on providing a rigorous description of key factors that influence the DRX process such as the effect of grain size, stacking fault energy, and other microstructural descriptors, thermomechanical processing, etc. The key addition of this work to existing literature is a critical commentary of important experimental as well as modeling efforts in recent years related to observing DRX in hexagonal close-packed (hcp) metals. We have attempted to directly compare, with reference to experiments, the effects of process variables such as strain rate, temperature, and composition on the occurrence of DRX in titanium alloys. A comprehensive review has been made of the experiments that have been carried out specifically to observe DRX in titanium alloys. This can aid modeling and validation efforts to accurately capture different facets of DRX for titanium alloys and other hcp metals. A similar comparison of the drawbacks and insights obtained from applying various modeling strategies, viz., FEM-based, phenomenological, or grid-based numerical methods for various alloys can provide valuable insights to choose appropriate modeling schemes or develop novel techniques to predict aspects of DRX such as preferred nucleation sites and evolution of microstructure, including grain boundaries and primary and secondary phases.
Unraveling the Hexaploid Sweetpotato Inheritance Using Ultra-Dense Multilocus Mapping
Authors: Mollinari Marcelo , Olukolu Bode A , Pereira Guilherme da S , Khan Awais , Gemenet Dorcus , Yencho G Craig , Zeng Zhao-Bang
Published: November 2019

The hexaploid sweetpotato (Ipomoea batatas (L.) Lam., 2n = 6x = 90) is an important staple food crop worldwide and plays a vital role in alleviating famine in developing countries. Due to its high ploidy level, genetic studies in sweetpotato lag behind major diploid crops significantly. We built an ultra-dense multilocus integrated genetic map and characterized the inheritance system in a sweetpotato full-sib family using our newly developed software, MAPpoly. The resulting genetic map revealed 96.5% collinearity between I. batatas and its diploid relative I. trifida. We computed the genotypic probabilities across the whole genome for all individuals in the mapping population and inferred their complete hexaploid haplotypes. We provide evidence that most of the meiotic configurations (73.3%) were resolved in bivalents, although a small portion of multivalent signatures (15.7%), among other inconclusive configurations (11.0%), were also observed. Except for low levels of preferential pairing in linkage group 2, we observed a hexasomic inheritance mechanism in all linkage groups. We propose that the hexasomic-bivalent inheritance promotes stability to the allelic transmission in sweetpotato.
A NovelcisElement Achieves the Same Solution as an AncestralcisElement During Thiamine Starvation inCandida glabrata
Authors: Iosue Christine L , Gulotta Anthony P , Selhorst Kathleen B , Mody Alison C , Barbour Kristin M , Marcotte Meredith J , Bui Lilian N , Leone Sarah G , Lang Emma C , Hughes Genevieve H , Wykoff Dennis D
Published: November 2019

Regulatory networks often converge on very similar cis sequences to drive transcriptional programs due to constraints on what transcription factors are present. To determine the role of constraint loss on cis element evolution, we examined the recent appearance of a thiamine starvation regulated promoter in Candida glabrata. This species lacks the ancestral transcription factor Thi2, but still has the transcription factor Pdc2, which regulates thiamine starvation genes, allowing us to determine the effect of constraint change on a new promoter. We identified two different cis elements in C. glabrata - one present in the evolutionarily recent gene called CgPMU3, and the other element present in the other thiamine (THI) regulated genes. Reciprocal swaps of the cis elements and incorporation of the S. cerevisiae  Thi2 transcription factor-binding site into these promoters demonstrate that the two elements are functionally different from one another. Thus, this loss of an imposed constraint on promoter function has generated a novel cis sequence, suggesting that loss of trans constraints can generate a non-convergent pathway with the same output.
Таксономічний склад деревних і кущових насаджень Уманського національного університету садівництва
Authors: Shlapak V. P. , Tysyachnyy O. P. , Vitenko V. A. , Koval S. A. , Maslovata S. V.
Published: November 2019

На підставі опрацювання літературних джерел досліджено історію створення зелених насаджень Уманського національного університету садівництва (УНУС). Проведено аналіз таксономічного складу автохтонних та інтродукованих деревних і кущових рослин, що нині зростають на цій території. Встановлено, що серед голонасінних рослин переважають представники роду Thuja та його формового різноманіття, дещо менше представництво має рід Picea, а третім за чисельністю є рід Pinus. Серед кущових порід порядку голонасінних переважають роди Juniperus і Taxus. Порядок покритонасінних рослин найбільше представлений родами Aesculus, Acer, Betula, Corylus, Juglans, Mahonia, Quercus, Ulmus, Tilia, Fraxinus, Salix та Sorbus. Найбільше представництво кущових рослин цього порядку становлять роди Berberis, Caragana, Cornus, Philadelphus, Laburnum, Viburnum, Spiraea, Symphoricarpos, Syringa, Tamarix та Forsythia. Для покращення естетичного стану цих насаджень необхідно проводити формувальну обрізку. Відзначено наявність великої кількості плодових рослин, яку представляють роди Armeniaca, Cerasus, Malus, Morus, Pyrus. Внаслідок проведеного візуального обстеження загального стану насаджень деревних та кущових рослин, що зростають на території УНУС, подано пропозиції щодо їх реконструкції та збільшення видового і формового різноманіття.
Використання різних способів розмноження береки лікарської за відновлення у свіжих дібровах Південно-Подільського лісостепу України
Authors: Shpak N. P.
Published: November 2019

Відтворення лісових насаджень за участю цінних видів деревних порід на сучасному етапі розвитку суспільства є актуальним завданням лісового господарства. Берека лікарська (Sorbus torminalis (L.) Crantz) – аборигенний вид, занесений до Червоної книги України (2009). Природний супутник лісових ценозів Південно-Подільського Лісостепу України, поновлення якого досліджували протягом п'яти років у деревостанах усіх вікових категорій та на зрубах, де залишені репродуктивні особини виду. Для дослідження кількісних та якісних показників поновлення Sorbus torminalis закладено 60 тимчасових та 11 постійних пробних площ. Природне насіннєве розмноження Sorbus torminalis виявлено у свіжих дібровах Південного Поділля. Насіння зберігає життєздатність 1-2 роки. У природних дубово-грабових насадженнях плодоношення настає в 20-річному віці, масове плодоношення спостережено раз у 5 років. Насіннєве розмноження використано для отримання сіянців і саджанців з метою введення Sorbus torminalis у культури дуба звичайного. Кращі результати отримано завдяки осіннім висівам свіжовимитого насіння за умов дотримання відповідних технологій. Осінні висіви здійснено у другій декаді вересня. Такі висіви дають весною дружні сходи і рівень їх ґрунтової схожості знаходиться в межах 78 %, що є досить успішним результатом для виду. Вегетативне порослеве розмноження сприяє її відновленню у разі механічних пошкоджень. Вирішення проблеми розмноження та оздоровлення породи можливе за умови використання сучасних досягнень біотехнології, одним з яких є метод мікроклонального розмноження. Цей метод дає можливість у стислі терміни одержати масовий, генетично однорідний садивний матеріал з високими спадковими властивостями продуктивності та стійкості до збудників хвороб. Для введення в культуру in vitro були верхівкові бруньки, нарізані з однорічних пагонів маточних рослин. Підібрано стерилізатори, а також визначено відповідні концентрації поживного середовища та експозиції. Впровадження різних способів розмноження береки лікарської сприятиме відновленню насаджень з її участю, а також розширення ареалу виду, що зникає.
Вартість відновлення екосистем малих міст Київщини як показник екозбалансованості
Authors: Zibtseva O. V. , Yukhnovskyi V. Yu.
Published: November 2019

Проаналізовано динаміку структури територій малих міст Київщини та визначено екозбалансованість територій шляхом порівняльного аналізу міст за вартістю відновлення їх екосистем. Вартість екостабілізувальних біотопів на 1 га міської площі розраховано для попереднього стану кожного міста і на 20-річну перспективу. Виявлено, що зростання площі відбувалося у 72 % малих міст із розширюванням їх забудови. Найвищим рівнем забудови характеризуються міста Вишневе, Переяслав-Хмельницький, Васильків, Фастів, а найменшим – Кагарлик і Яготин. Значна частка в загальній площі міських біотопів належить присадибним садам, питома вага яких змінюється в межах від 4 до 30 %. Орні землі представлені вкрай нерівномірно і в деяких містах відсутні, хоча їхня частка в окремих містах сягала 80 %, а в перспективних планах – 50 %. Ліси відсутні на території третини дослідних міст. Площа водних поверхонь найістотніше позначається на вартості біотопів, характеризується нерівномірним розподілом і її частка сягає 30 %. Здебільшого присадибні сади займають найбільшу питому вагу в загальній вартості міських біотопів. В окремих випадках їм належить до 85 % вартості. Найбільший відсоток лісів у загальній вартості відзначено для міст Ржищів, Вишгород, Ірпінь, а водойм – для міст Яготина, Тетієва, Миронівки, Богуслава, Кагарлика. Ці показники важливо враховувати у перспективних планах розвитку міст, де для обґрунтування нормативної площі зелених просторів потрібно брати не тільки рекреаційні норми зелених насаджень загального користування, а сукупність екосистемних послуг багатофункціональних зелених територій, які гарантуватимуть екозбалансований розвиток територій.
Культивари виду Thuja plicata Donn ex D. Don у Правобережному Лісостепу України та можливості їх використання в садово-парковому будівництві
Authors: Ivashchenko I. Ye.
Published: November 2019

Досліджено внутрішньовидове різноманіття виду Thuja plicata Donn ex D. Don у Правобережному Лісостепу України. Встановлено, що із 54 відомих культиварів виду в дендрологічних парках регіону вже багато років успішно зростають два: Th. p. 'Zebrina' і Th. p. 'Aureovariegata'. За останні 10 років також були введені Th. p. 'Dura' та Th. p. 'Whipcord'. У декоративному садівництві поширені такі культивари Th. plicаta: Th. p. 'Atrovirens', Th. p. 'Aureovariegata', Th. p. 'Can-Can', Th. p. 'Daniellow', Th. p. 'Dura', Th. p. 'Excelsa', Th. p. 'Gelderland', Th. p. 'Goldy', Th. p. 'Kornik', Th. p. 'Whipcord', Th. p. 'Zebrina' та Th. p. 'Zebrina Extra Gold'. Для характеристики різноманіття культиварів Th. plicаta, що ростуть у Правобережному Лісостепу України, використано систему класифікації формового складу поліваріантних видів Р. В. Кармазіна. Згідно з цією класифікацією, досліджувані рослини Th. plicаta належать до надгрупи В (рослини з лускоподібною хвоєю). Із 12 культиварів до групи І віднесено шість; до групи ІІ – три; до групи ІІІ – три. Визначено біометричні показники досліджуваних культиварів. Виділено культивари Th. plicаta, які поширені в районі досліджень за найбільш істотними декоративними ознаками, а саме: за забарвленням хвої, формою крони та висотою (низькорослі форми). Враховуючи їхні декоративні якості, надано рекомендації щодо застосування у різних типах насаджень: солітерах, групах, алеях, живоплотах, під час створення альпінаріїв та контрастних композицій.
Особливості росту і розвитку рослин роду Corylus L. залежно від впливу оптичного випромінювання в умовах Правобережного Лісостепу України
Authors: Kosenko I. S. , Balabak O. A. , Balabak A. V.
Published: November 2019

Наведено результати досліджень особливостей росту і розвитку рослин фундука в умовах насаджень. Продуктивність рослин фундука насамперед пов'язана з фотосинтетичною активністю листків. Тому формування конструкцій насаджень істотно впливає на рівень плодоношення фундука. Створення різних конструкцій в поєднанні з урахуванням сортових особливостей фундука сприяє оптимальному розміщенню рослин у насадженнях і забезпечує їхню високу врожайність. Освітлення погіршується з ростом і розвитком рослин фундука і починає впливати на рівень плодоношення на 5-6 рік після закладення насаджень. У всіх досліджуваних сортів фундука незалежно від сили росту за форми крони "Кущ", нижня частина перебуває в умовах недостатнього освітлення – 19-30 %, яке не перевищує мінімального порогу – 30 % від відкритої поверхні. У середній частині крони рівень освітлення також був досить низький – 55-65 %. Найбільш освітленою виявилася верхня частина крони, світловий режим якої становив – 80-94 % від повної освітленості на відкритій поверхні. Погіршення рівня освітленості в контрольному варіанті "Кущ" відбулося через постійний ріст пагонів та їх загущення. Окрім цього, відбулося змикання рослин фундука в лінії ряду, що значно утруднювало проникнення сонячного світла в середину крони. У насадженнях із конструкціями насаджень "Вогнище", "Дерево" та "Татура" складався більш сприятливий, порівняно з контролем, світловий режим, що є наслідком оптимального розміщення стовбурових пагонів та гілок у кроні рослини фундука. У варіантах досліду "Вогнище", "Дерево" та "Татура" перевищення мінімального порогу освітлення у низькорослих сортів спостережено на висоті 0,5 м від поверхні ґрунту, що позитивно впливало на плодоношення рослин фундука під час застосування цих конструкцій насаджень. Тобто ступінь освітлення більше залежить від формування конструкцій насаджень, ніж від сортових особливостей рослин фундука, і отримані показники свідчать про значну перевагу освітленості конструкцій "Вогнище", "Дерево" та "Татура", порівняно з контролем. Найбільш розріджену схему садіння рекомендовано застосовувати для високорослих сортів фундука під час використання конструкцій насаджень "Кущ" і "Вогнище" – 6×6 м. Найщільнішу схему садіння доцільно використовувати для низькорослих сортів фундука за формування конструкції насадження "Дерево" і "Татура" – 3×5 м.
Особливості вирощування Sophora Japonica L. у садово-паркових господарствах
Authors: Kurka S. S.
Published: November 2019

Наведено узагальнені результати літературного огляду інтродукції і використання в Україні Sophora japonica L. Оцінено перспективність та успішність інтродукції Правобережному Лісостепу та Степу України. Досліджено успішність інтродукції Sophora japonica L. в умовах Правобережного Лісостепу і Степу України методом інтегральної числової оцінки життєздатності та перспективності інтродукції дерев на підставі візуальних спостережень, який враховує найважливіші для інтродукції показники: ступінь визрівання пагонів, зимостійкість, збереження габітусу, пагоноутворювальна здатність, регулярність приросту пагонів, здатність до генеративного розвитку. Визначено ступінь акліматизації інтродукованого виду Sophora japonica L. методом встановлення акліматизаційного числа. Досліджено декоративність рослин Sophora japonica L. в умовах Правобережного Лісостепу і Степу України. Оцінено декоративність та запропоновано практичні рекомендації щодо перспектив використання Sophora japonica L. у зеленому будівництві. Відзначено високі адаптаційні можливості виду. Встановлено, що Sophora japonica L. є перспективною рослиною для інтродукції на цій території. Sophora japonica L. не має широкого впровадження в озелененні, оскільки недостатньо повно висвітлено науково обґрунтовані дані з вивчення її інтродукції в умовах Правобережного Лісостепу України. Тому виникає необхідність виконання роботи, що полягає в узагальненні досвіду інтродукції Sophora japonica L. в цьому регіоні.