bluuebunny/crossref_metadata_2025 huggingface dataset:
Correction of hepatorenal syndrome with the use method of indirect electrochemical detoxification in oncological patients on the background of enteral insufficiency after multi-organic surgeries
Authors: Pavliuchenko Oleksii , Krutko Yevhen , Matvieienko Mariia , Pilipenko Sergey , Podrez Eduard , Shulga Mykola , Shulga Yevheniia
Published: April 2023

Introduction. Enteral insufficiency syndrome accompanies the development of many acute diseases of the abdominal cavity. According to statistics, as a result of advanced and multi-organ surgery in oncosurgery for 2019–2020, enteral insufficiency was a complication in 39 % of all cases, regardless of anatomical and physiological area, and complications such as hepatorenal syndrome – in 50–80 % cases. The aim of the work is to study the effectiveness of correction of hepatorenal syndrome on the background of enteral insufficiency in cancer patients after multiorgan surgery. To do this, we used the method of indirect electrochemical detoxification with a solution of sodium hypochlorite. Materials and methods. 71 patients with oncopathology who underwent multiorgan surgery in different anatomical and physiological areas were examined. Patients were divided into two groups: the main group (n = 36), in which indirect electrochemical detoxification was performed with sodium hypochlorite solution at a concentration of 0.03 ; the comparison group (n = 35) – treatment was carried out according to standard schemes. The groups were compared by age and anatomical and physiological areas that were operated on (surgery was performed on the chest and mediastinum and abdominal organs). Results and discussion. For the treatment of patients with enteral insufficiency used the method of electrochemical detoxification with sodium hypochlorite, which reduces the indicators that reflect blood toxicity and the degree of intoxication. This was evidenced by a decrease in the concentration of bilirubin by 23.1 %, urea by 20.6 %, creatinine by 23.4 %, ALT by 57.2 % alkaline phosphatase by 69.5 %. When using this method for the third day managed to get a detoxifying effect. Conclusions. The expediency of including sodium hypochlorite in the complex postoperative therapy is shown. This is proved by the results of a comprehensive study of cancer patients after multiorgan surgery with the development of hepatorenal syndrome on the background of enteral insufficiency. It was found that the use of infusions of 0.03 % NaClO solution has a detoxifying effect: significantly reduces elevated concentrations of bilirubin by 23.1 %, creatinine by 20.6 %, urea by 23.4 %, improves the rheological properties of the blood. Therefore, given the relatively low effectiveness of conservative and insufficient availability of surgical treatment along with high mortality, prevention of hepatorenal syndrome in patients with enteral insufficiency by indirect electrochemical detoxification can significantly reduce its incidence.
Effects of public health emergencies of international concern on disease control: a systematic review
Authors: de Araújo Giovanna Rotondo , de Castro Pedro A.S.V. , Ávila Isabela R. , Bezerra Juliana Maria T. , Barbosa David S.
Published: April 2023

Objectives.

To assess the accumulated knowledge of the effects of public health emergencies of international concern on disease control and local health systems, and contribute to a better understanding of their effects on health programs and systems.

Methods.

This was a systematic review of published and gray literature (in English, Portuguese, or Spanish). Electronic databases (BVS/LILACS, PubMed, and SciELO) and Google Scholar were searched. Search terms were: COVID-19 OR H1N1 OR Ebola OR Zika OR poliomyelitis AND (outbreaks OR epidemics) AND (public health systems OR public health surveillance).

Results.

A total of 3 508 studies were retrieved, of which 31 met the inclusion criteria. The studies addressed the effects of the emergencies on: communicable diseases notification systems; malaria, HIV/AIDS, tuberculosis, poliomyelitis, and malaria surveillance, control, and treatment; microcephaly; dengue; and vaccinations. The populations affected by the emergencies experienced reduced health services, which included fewer health visits, failures in the diagnostic chain, decrease in vaccination, and increased incidence or underreporting of notifiable diseases.

Conclusions.

Socioeconomic inequity is a determinant of the effects of public health emergencies of international concern within affected populations. The diversion of resources and attention from health authorities disproportionately affects vulnerable populations and can lead, over time, to a weakening of health systems. The analysis of the effects of public health emergencies is important for the development of new protocols that can better respond to future crises.
The Puzzle of Wine Price in Restaurants
Authors: Livat Florine , Remaud Hervé , McHale Anne
Published: April 2023

There is large variation amongst food service operators in pricing wine, and many questions remain about how wine is priced and what objectives are used to determine wine price in restaurants. In this essay-style article, we examine the practices that the industry have adopted when pricing wine in restaurants. Beyond the basic rule of thumb – applying proportionally smaller mark-up to higher-priced wines –, pricing can be driven by the market, customer or competition. The restaurant’s characteristics as well as institutional and environmental factors can influence the price of wine at restaurants.
Luces y sombras de la Tecnología
Authors: Hugo Diana Victoria , Olavegogeasoechea Mara , Olea Patricia , Ávila Silvia , Farias Nanci
Published: April 2023

Esta ponencia muestra una unidad didáctica diseñada dentro del Proyecto Iberoamericano sobre la Naturaleza de la Ciencia y la Tecnología (EANCYT) EDU2010-16553 financiado por Plan Nacional de I+D del Ministerio de Ciencia e Innovación (España), que busca promover en futuros profesores de ciencias y de enseñanza primaria mejor comprensión de la naturaleza de la ciencia y la tecnología. Pretende que evolucionen algunas actitudes/creencias reduccionistas detectadas en el anterior Proyecto Iberoamericano de Evaluación de Actitudes Relacionadas con la Ciencia, la Tecnología y la Sociedad (PIEARCTS) respecto a las decisiones tecnológicas de un país. Plantea inicialmente la catástrofe de Fukushima, los cuestionamientos que surgen a las políticas energéticas globales relacionados con el uso de la energía nuclear versus energías mas limpias, para focalizarse finalmente en la complejidad y diversidad de condicionantes que se ponen en juego en tales decisiones. Propone actividades que desarrollan competencias cognitivo- linguísticas, metacognitivas, procedimientos y actitudes asociados a la sustentabilidad. Se evaluará el impacto de la unidad didáctica en distintos contextos/ géneros a través de un pre y post test a aplicar a dos muestras de alumnos de 18 y 22 años divididos en grupo experimental y grupo control, usando como instrumento el cuestionario estandarizado de opiniones sobre ciencia, tecnología y sociedad (COCTS).
Kierunek Wschód. Kulisy realizacji filmu "Mamo, czy kury potrafią mówić?"
Authors: Szul Szymon
Published: April 2023

The author analyses the first, unsuccessful Polish-Belarusian co-production of the Semafor Film Studio – "Mamo, czy kury potrafią mówić?". The project, which was initially planned as another, simple in terms of complexity of the studio’s film production, became one of the studio’s largest and most demanding projects. The researcher tries to shed some light on what the reasons behind this decision were. Using archive data and information obtained in the process of conducting in-depth interviews with former employees of Semafor, he places the studio in the broader landscape of film production, and indicates what factors determined the final failure of the project as a co-production with the Belarusians.
Technology for Assessing the Level of Competence Formation of a Graduate of Technical University
Authors:   Kazan State Power Engineering University, Kazan, Russia, Zakieva Rafina ,   Institute of Education Development Strategy of the Russian Academy of Education, Moscow, Russia, Leontiev Alexander ,   Kazan State Power Engineering University, Kazan, Russia, Serikov Vladislav ,   Institute of Education Development Strategy of the Russian Academy of Education,  Moscow, Russia
Published: April 2023

The main idea behind this research is to create and use a system for managing the quality of university education based on criterion scoring and monitoring of professional student development, the comparison of information received with the graduate requirements specified in the Federal State Educational Standard for Higher Education (FSES HE) in engineering and the adjustment of didactic conditions for professional and personal student development based on these indicators. The availability of such information provides the possibility to compare the actual student development with FSES HE requirements for a particular field of education. It also gives the opportunity to modify the educational process and identify “gaps” in contents, technologies and other characteristics of educational process and make the appropriate changes. The technology that is used to evaluate the maturity level of a future engineer’s competence does not represent the evaluation of education quality as such. However, it creates a continuously updating database for implementing such evaluation. It is used to determine the effectiveness of contents, methods, means and forms of educational activities, etc. The suggested technology can be applied as a specific tool for “deciphering the gaps” identified in students or, in other words, for discovering failures in educational process management. By assessing the gaps in students’ knowledge, skills and thoughts it is possible to discover the “failures” in educational process and the aspects that have gaps and “defects”.
Being and becoming
Authors: Markou Smaro
Published: April 2023

This paper is a personal testimony, a short account of my experience of suffering from the side effects of covid-19 on underlying heart disease. Writing from within moments of pain and agony, I unfold my inner journey to the void and back. Reflecting on that journey I offer my thoughts, born upon my contact with therapists, doctors, and nurses in the hospitals where I was treated, and my inner dialogue with the voices of many people who have nourished my thinking and practice all these years. Traveling through the unknown conditions of my illness and recovery, who I am and who I am becoming personally and professionally, have been in constant movement and intra-action. From this place I offer some reflections on identity, power and on being a therapist.
Getting On With Pain
Authors: McCarthy Judy
Published: April 2023

This paper provided the welcome opportunity to write about how I have come to understand and relate to chronic pain. My systemic psychotherapy training and interest in Narrative Practice has strongly influenced my conceptualisation of pain. I have found this useful in my experience of living with chronic pain. I hope the reader is invited to reflect on the many dimensions of pain and illness and the multitude of possibilities for understanding and relating to it.  I experience pain as a very significant aspect of my life and my relationships including therapeutic relationships. For this reason, I believe it is important to talk about the therapist’s illness and health conditions in the same way that other aspects of human experiences are talked about.
Uniseco do Brasil: Repercussão de pré-fabricação do pós-segunda guerra
Authors: Camargo Monica Junqueira de
Published: April 2023

A experiência pioneira de pré-fabricação realizada nos anos 1950 pela Uni-seco do Brasil foi apoiada em patente
desenvolvida durante o programa oficial de reconstrução inglesa no pós-segunda guerra, quando se consolida na
Europa campo prático para aplicação da arquitetura moderna, incorporando a racionalização e a pré-fabricação. A
patente é trazida ao Brasil, em contexto de grande euforia econômica, de modernização da construção, e otimismo
com os recursos e as possibilidades da recente industrialização nacional. Caracterizada por sistema modular de
componentes em ciclo fechado de produção, a Uni-seco atendeu a programas de residências particulares, usos
coletivos, como a sede de um clube e uma lanchonete no Parque Ibirapuera em São Paulo, e residências econômicas
promovidas pelo Instituto de Pensões do Estado de São Paulo (IPESP). Com caráter experimental e propositivo de
novos paradigmas, por uma nova arquitetura e por novos moldes de construção, contou com a participação do
arquiteto Eduardo Kneese de Mello - desencadeando alternativas em sua produção posterior, em sintonia com
desenvolvimentos da arquitetura moderna brasileira, para maior industrialização na construção civil, em momento de
maior respaldo e conhecimentos sobre a questão.
Palavras-chave: Uni-seco; sistemas construtivos; arquitetura moderna; habitação; pré-fabricação.
The Relevance of structured onboarding in the assimilation of organizational culture
Authors: Gomes Rickardo  , Sousa Daniele
Published: April 2023

This article presents as its theme the relevance of structured onboarding in the assimilation of organizational culture. In this context, the conceptualizations related to organizational culture were developed based on the research of several authors who deal with the onboarding theme. The general objective of this scientific article, taking into consideration the theoretical definitions used in the development of this work, was to analyze the relationship and impacts that the onboarding process has on organizational culture. The specific objectives established seek to reflect and describe the onboarding process, the relationship with the Human Resources sector and organizational culture, and finally, to analyze how a structured process aligned with organizational culture occurs. In this context of objectives, this article used bibliographic research methodology, through theoretical sources that provide data to be explored. Following this perspective, it was found that the impact of the employee's onboarding strength contributes to the appropriation of organizational culture. It is concluded, therefore, that the importance of the notions of organizational culture are better assimilated in the work environment from the perspective of a structured onboarding process.
Selective grinding and neuro-occlusal rehabilitation
Authors: Amel BELKHIRI  , Fatma Si Ahmed
Published: April 2023

The characteristics of the modern human diet do not favour normal tooth wear. This lack of evolution of the occlusal morphology will be responsible for limitations in mandibular lateral movements and masticatory work. When masticatory impotence is detected, artificial wear of the cuspid reliefs should be performed as soon as possible. These grindings, called selective by Pedro Planas, make it possible to free the mandibular lateral movements and to rehabilitate the masticatory function. Physiological, unilateral and alternating chewing function allows for «happy growth» of the jaws and maintenance of a healthy masticatory system.
Mature ovarian teratoma in a newborn: A case report
Authors: Imane ZIZI  , Ilham ELOUARDIGHI  , Najat AMALIK  , Lamiae ELIAZIJI  , Houria KENOUNI  , Amina BARKAT
Published: April 2023

Mature cystic ovarian teratomas, also called dermoid cysts, are one of the most frequent ovarian tumors and are suggested when a fat-containing cystic tumor is identified on imaging. Knowledge of the imaging features of these tumors allows for a confident diagnosis to be made in most cases. Treatment is usually based on surgical resection, which is preferably carried out by laparoscopic way.
Von Willebrand disease in a neonate: A case report
Authors: Imane ZIZI  , Ilham ELOUARDIGHI  , Najat AMALIK  , Lamiae ELIAZIJI  , Houria KENOUNI  , Amina BARKAT
Published: April 2023

Von Willebrand disease (VWD) is a constitutional bleeding disorder of autosomal inheritance characterized by a quantitative or functional abnormality of the factor Willebrand. We report the observation of a neonate with a confirmed diagnosis of von Willebrand disease in the neonatal period. This disease is a very heterogeneous clinically, phenotypically and genetically, and poses a diagnostic difficulty. The biological diagnosis is based on first-line tests (prothrombin level and activated partial thromboplastin time) completed by the measurement of the coagulant activity of factors VIII, IX and XI, as well as the activity and antigen of Von Willebrand factor (VWF). The treatment strategy for VWD should be considered in collaboration with a hematologist aiming to correcting VWF and factor VIII levels. Therefore, a recombinant VWF concentrate has recently been introduced and has proven to be effective.
Nomenclatural standards of pear varieties bred by Sverdlovsk Horticultural Breeding Station
Authors: Bagmet L. V. , Tarasova G. N.
Published: April 2023

As part of the research there have been developed and published nomenclatural standards of 12 pear varieties bred by Sverdlovsk Horticultural Breeding Station: Berezhenaya (WIR-101392), Gvidon (WIR-101393), Dobryanka (WIR-101394), Zarechnaya (WIR-101395), Permyachka (WIR-101397), Raduzhnaya (WIR-101398), Rozovyy Bochonok (WIR-101399), Sverdlovchanka (WIR-101400), Sultan (WIR-101402), Talitsa (WIR-101404), Fleyta (WIR-101405), Chusovaya (WIR-103944). Plant material for nomenclatural standards was selected in the collection of the originator organization with the participation of the creators of these varieties. The herbarium sample of the nomenclature standard of each cultivar is represented mainly by two herbarium sheets containing parts of one plant collected during two periods: fruit and annual shoots ‒ in the fall 2019, flowers ‒ in the spring 2020. The herbarium label indicates: the herbarium number of the sample in the VIR Herbarium, the scientific name of the species, the name of the variety, the origin (the name of the organization in which the variety was created), the place of reproduction (where the plant was grown), the harvest dates, the names of collectors. Herbarium sheets are supplemented with photos of fruits and flowers. Nomenclatural standards are made in accordance with the recommendations of the International Code of Nomenclature for Cultivated Plants (ICNCP), registered in the database "VIR Herbarium" and included in the type collection of Herbarium of cultivated plants of the world, their wild relatives and weeds (WIR). According to the same rules, herbarium samples of 3 elite pear forms (Limonadnaya, Sretenskaya, Tais) were made, registered and included into the Main Fund of the VIR Herbarium. After registration of copyright documents for cultivars, these samples can be assigned as nomenclatural standards. In total, 27 samples in the amount of 27 herbarium sheets were transferred to the herbarium collection. A digital image of herbarium specimen is available in the database «VIR Herbarium» (http://db.vir.nw.ru/herbar/gerb).
The assessment of blue lupine varieties according to productivity and adaptability in the conditions of Kirov region
Authors: Kislitsyna A. P. , Popov F. A. , Svetlakova E. V. , Sofronova A. Yu.
Published: April 2023

The article provides the results of the comparative study of grain productivity of 7 blue lupine (Lupinus angustifolius L.) varieties bred by the All-Russian Scientific Research Institute of Lupine in the conditions of Kirov region on sod-podzolic light loamy soil. It has been established that the yield of the seeds of blue lupine varied 1.5-2 times over the years of cultivation (2000-2022) depending on the weather conditions. Over 3 years on the average the varieties Bryansky kormovoy and Siderat were the most productive, 46-287 and 281 g/m2, respectively. Even in extremely unfavorable for blue lupine 2022 (by environment condition index of 62) these varieties significantly exceeded the control (Vitayz – 135.8 g/m2) in yield, by 72.9 and 61.1 %. The coefficient of adaptability of the varieties Siderat 46, Smena, Uzkolistny 53, Bryansky kormovoy was over 100 %. The productivity structure elements of blue lupine, namely: the number of beans per plant, the number of grains per bean and mass of 1000 seeds depended on hydrothermal conditions of the growing period. Under favorable conditions the number of beans per plant and the size of seeds increased. The number of grains per bean was the most stable indicator. The average duration of the growing period of lupine varieties was 84-91 days. In hot and dry weather of 2022 the ripening began 5-7 days earlier than long-time average annual periods. The varieties with highly developed side branching had a longer growing period – Bryansky kormovoy, Uzkolistny 53 and. Vitayz. During the year favorable by hydrothermal conditions the raw protein content in lupine seeds was 30.8-36.5 %. In unfavorable years it decreased by 20-45 % depending on the variety.
Development of technology for standardization of parameters of winter route registration of game animals
Authors: Glushkov V. M. , Solovyev V. A. , Shevnina M. S.
Published: April 2023

The need to develop a new technology for planning survey routes is caused not only by the difficulty of implementing the recommendations of the current methodology for winter route accounting (ZMU) for the “equidistant placement” of survey routes with “observance of a proportional survey of land categories forest, field, swamp”, but also by the inability of the method of grouping the sample into categories of land to reduce the heterogeneity of the examined material. To standardize the placement of accounting routes, the technology of stratification of the territory is put, in which the virtual boundaries of the stratum serve to determine the extrapolation area and the location of the survey route. For the total area of the hunting farm, a tabular, or calculated (for farms with a different area), value of the route length standard, km/thousand ha, is established. The free navigation program SAS Planet determines the length and width of the territory within the boundaries of the hunting area and the principle layout of the registration routes in the strata. According to the algorithms, the following parameters are calculated: the total length of the routes, the average values of the length and width of the territory, the number of strata, the distance between the registration routes, the length of the route in the stratum, the area of the strata, which are necessary for designing the stratification of the territory. On the example of a specific farm with unknown values of parameters, except for the area of the territory, the suitability of algorithms for calculating parameters is shown; a map of the boundaries of the strata and the location of the accounting traces was created; the area of the strata and the design length of the registration route in each stratum were determined; digitized files of traces necessary for work on their reference to the terrain have been created; the technology of binding is given. The results of the study confirmed the manufacturability and simplicity of the method for localizing routes and extrapolation sites, as well as the compatibility of their ordered placement in compliance with a standardized sample size for territories with any area and boundary configuration.
Die neue Familie
Authors: Walter Alfred
Published: April 2023

Der Artikel reflektiert unter Beachtung neuerer familiensoziologischer Untersuchungen die von gesellschaftlicher und ökonomischer Seite zunehmenden mehrdimensionalen Belastungen, die moderne Familien zu schultern haben. Auch die mit dem modernen Selbstverständnis der Familie verbundenen Werthaltungen gemeinsamer Elternschaft und des damit verbunden zunehmenden Engagements der Väter birgt aufgrund der ihnen inhärenten Infragestellung traditioneller Rollenmuster latente Konfliktpotenziale in sich, die im familiären Alltag immer wieder durchbrechen. Ausgehend von einer paarund familientherapeutischen Erfahrungsperspektive werden daraus resultierende Belastungsdynamiken angesprochen, in denen sich diese Faktoren innerfamiliär niederschlagen. Hierbei versuchen Familien, strukturell bedingte Belastungen auf individueller Ebene in den Griff zu bekommen, was letztlich nur durch eine andere Wirtschaftsund Familienpolitik zu lösen ist. Entsprechend spricht sich der Autor für ein zivilgesellschaftliches Engagement in Richtung einer mehr entwicklungsfördernden familienorientierten Vernetzung im gesellschaftlichen Nahbereich aus, statt Familienpolitik reflexhaft dem Primat ökonomischer Interessen zu opfern.
Forschung zur Mentalisierungsfördernden Verhaltenstherapie
Authors: Theßen Lars , Sulz Serge K. D. , Wedlich Kurt , Keim Pia , Hofherr Lukas , Leiner Rebecca , Schick Paulina , Wöhrle Katharina , Bohn Anna , Rose Janina , Cozzi Isabelle
Published: April 2023

Wir berichten über eine Untersuchungsreihe zur Validierung der theoretischen Konstrukte der Mentalisierungsfördernden Verhaltenstherapie (MVT). Unabhängige Variable sind die Entwicklungsstufe, die Bindungssicherheit im engeren Sinne und übermäßig frustrierendes Elternverhalten in der Kindheit. Abhängige Variable sind Persönlichkeitsdefizite (VDS30), Persönlichkeitsstärken (VDS19+), mentale Ressourcen (VDS38 RDR) und Mentalisierungsfähigkeit (VDS48). Wir finden zahlreiche hochsignifikante Korrelationen, die für die Gültigkeit der affektiv-kognitiven Entwicklungstheorie von Sulz (1994, 2017a, b) sprechen. Erste Ergebnisse von Outcome-Studien werden berichtet.
Was ist Mentalisierungsfördernde Verhaltenstherapie (MVT)?
Authors: Theßen Lars , Sulz Serge K. D.
Published: April 2023

Mentalisierungsfördernde Verhaltenstherapie (MVT) ist eine Weiterentwicklung der Strategisch-Behavioralen Therapie (SBT). Zu deren Therapiemodulen werden zwei neue Module hinzugefügt: Emotion Tracking – eine Adaption von Albert Pessos Microtracking zur Anwendung in der Kognitiven Verhaltenstherapie (KVT) – und Mentalisierungsförderung – eine Adaption der MBT-Fragetechnik. Während die Mentalisierungsbasierte Therapie (MBT) eine psychoanalytisch begründete Therapiemethode innerhalb der Psychodynamischen Therapie ist, ist das Mentalisierungsmodul der MVT ein kognitiv-behaviorales Instrument zum Aufbau einer realitätsgerechten Theory of Mind (TOM). Diese beiden Module sind zum Kern der MVT geworden und sind damit eine allgemeine psychotherapeutische Basiskompetenz, die u. E. in keiner Therapie fehlen darf. Die Behandlung schreitet vom ersten Modul (sichere Bindung in der therapeutischen Beziehung herstellen) zum zweiten Modul (die dysfunktionale Überlebensregel aus den Verletzungen der Kindheit extrahieren und in eine Erlaubnis gebende Lebensregel verwandeln) weiter zum dritten Modul (durch Achtsamkeit Gefühle wahrnehmen und akzeptieren). Daran schließen die beiden genannten neuen Module Emotion Tracking und Mentalisierungsförderung an, gefolgt von den beiden Entwicklungsmodulen (Entwicklung von der Affektauf die Denken-Stufe und Entwicklung von der Denkenauf die Empathiestufe), deren Ziel funktionale Affektregulierung und Beziehungsfähigkeit im Sinne von Empathie und Mitgefühl ist.
MONITORING DATA AGGREGATION OF DYNAMIC SYSTEMS USING INFORMATION TECHNOLOGIES
Authors: Shevchenko Dmytro , Ugryumov Mykhaylo , Artiukh Sergii
Published: April 2023

The subject matter of the article is models, methods and information technologies of monitoring data aggregation. The goal of the article is to determine the best deep learning model for reducing the dimensionality of dynamic systems monitoring data. The following tasks were solved: analysis of existing dimensionality reduction approaches, description of the general architecture of vanilla and variational autoencoders, development of their architecture, development of software for training and testing of autoencoders, conducting research on the performance quality of autoencoders for the problem of dimensionality reduction. The following models and methods were used: data processing and preparation, data dimensionality reduction. The software was developed using the Python language. Scikit-learn, Pandas, PyTorch, NumPy, argparse and others were used as auxiliary libraries. Obtained results: the work presents a classification of models and methods for dimensionality reduction, general reviews of vanilla and variational autoencoders, which include a description of the models, their properties, loss functions and their application to the problem of dimensionality reduction. Custom autoencoder architectures were also created, including visual representations of the autoencoder architecture and descriptions of each component. The software for training and testing autoencoders was developed, the dynamic system monitoring data set, and the steps for pre-training the data set were described. The metric for evaluating the quality of models is also described; the configuration of autoencoders and their training are considered. Conclusions: The vanilla autoencoder recovers the data much better than the variational one. Looking at the fact that the architectures of the autoencoders are the same, except for the peculiarities of the autoencoders, it can be noted that a vanilla autoencoder compresses data better by keeping more useful variables for later recovery from the bottleneck. Additionally, by training on different bottleneck sizes, you can determine the size at which the data is recovered best, which means that the most important variables are preserved. Looking at the results in general, the autoencoders work effectively for the dimensionality reduction task and the data recovery quality metric shows that they recover the data well with an error of 3–4 digits after 0. In conclusion, the vanilla autoencoder is the best deep learning model for aggregating monitoring data of dynamic systems.
THERMAL PROCESSES OF FIRE DETECTORS’ HEAT-RESISTANT SENSITIVE ELEMENTS
Authors: VASILYEVA О. , KOZAK Ya.
Published: April 2023

The purpose of the article. The article deals with thermal processes in the heat-resistant sensitive element of fire detectors when an electric current flows through it. Such processes are described by an inhomogeneous equation of mathematical physics with boundary conditions of the third kind. Methodology. The Hankel integral transformation is used to solve the differential equation that describes the thermal processes in the heat-resistant sensitive element of fire detectors. As a result of the transformations, a general expression was obtained for the temperature of the heat-resistant sensitive element of fire detectors under the condition that an electric current flows through it without restrictions on its parameters. This expression is represented as a series of Bessel functions. Results. The results of scientific research confirmed that due to the small size of the fire detectors’ sensitive element, the expression for its temperature is presented in the form of an average value over the sensitive element volume. Scientific novelty. For the first time, a general expression for the temperature of the heat-resistant sensitive element of fire detectors is obtained, which allows obtaining its main technical characteristics, and also serves as a basis for moving to other mathematical descriptions. Practical value. Also, using the integral Laplace transformation, an expression for the transfer function of the fire detectors’ heat-resistant sensitive element was obtained and it was confirmed that with an error of no more than 4,6 %, it is described by the transfer function of the inertial link.
NEW UNDERSTANDING OF THE ARCHITECTURAL AND URBAN PLANNING ENVIRONMENT FORMATION DURING OBJECTS’ CREATION ON EARTH AND OTHER PLANETS
Authors: VOROBIOV V. , SHYLO О.
Published: April 2023

Problem statement. The ХХth century was the time of developing unique architectural and urban planning projects for the Earth the exploration of other planets. This work continues even now, due to the development of knowledge in the engineering and technology, materials science, construction and related technologies, and many other areas. Including space vectors of economic, political, scientific, military, medical, evolutionary and other interests of people. The development of new objects is traditionally dominated by outdated scientific ideas about the essence and properties of space, the essence and properties of man and people's reflexions on themselves and their environment. On the other hand, in scientific communities, during the same ХХth − early ХХIst centuries, three theoretical directions of knowledge were formed that radically change the idea of the space and time existence, in which the architect is thought to create his objects; the existence of matter (the substance from which cities and buildings in them are built); what is the discrete and probabilistic structure of Being, and how we should now relate to it. Three directions of knowledge that have revolutionised the understanding the foundations of the Universe from the microscale to Universal processes are the general theory of relativity, quantum mechanics and the theory of loop gravity. A critical analysis of contemporary architecture and urban planning has led to the conclusion that, based on new knowledge, approaches to the formation of the anthropogenic environment, created both for conditions on Earth and for other planets have to be reconsidered also. The purpose of the article − to reveal a new understanding for foundations of the architectural and urban environment formation during objects’ creation on Earth and other planets.
SPATIAL CHARACTERISTICS OF EU-FUNDED TOURISM INVESTMENTS IN THE NORTHERN GREAT PLAIN REGION (HUNGARY) IN THE 2014-2020 BUDGET PERIOD
Authors:   University of Debrecen, Faculty Department of Social Geography and Regional Development Planning, Debrecen, Hungary, BADAR Zoltán , KOZMA Gábor ,   University of Debrecen, Faculty Department of Social Geography and Regional Development Planning, Debrecen, Hungary, MONYÓK Bence ,   University of Debrecen, Faculty Department of Social Geography and Regional Development Planning, Debrecen, Hungary
Published: April 2023

The aim of this paper is to present the territorial characteristics of explanation of European Union funding for tourism-related developments in the Northern Great Plain region (Hungary) in the 2014-2020 programming period of the European Union. We relied fundamentally on the website “palyazat.gov.hu” as our source, which provides information on the number of grant applications submitted and those that were successful. There are very significant differences between counties and settlements in terms of the application activity and the focus of the applications. Firstly, the specificities of the counties that make up the Northern Great Plain region had a significant impact on the region’s performance in case of national-level projects. Secondly, hand the influencing factors include the commitment of the leaders of the individual counties and settlements to tourism, the impact of the conditions set out in the calls for applications, as well as the role of political lobbying.
MANGROVE POTENTIAL ASSESSMENT FOR DETERMINING ECOTOURISM ATTRACTION AND STRENGTHENING DESTINATION BRANDING AND MARKETING: ”GUNUNG PITHING MANGROVE CONSERVATION”, INDONESIA
Authors:   Universitas Brawijaya, Fisheries Agribusiness Study Program, Fisheries Socioeconomic Department, Faculty of Fisheries and Marine Sciences, Malang, Indonesia, ABIDIN Zainal , NURYANI Fadhilah Estu ,   Universitas Brawijaya, Marine Sciences Study Program, Faculty of Fisheries and Marine Sciences, Universitas Brawijaya, Malang, Indonesia, SAPUTRA Dhira Khurniawan ,   Universitas Brawijaya, Marine Sciences Study Program, Faculty of Fisheries and Marine Sciences, Universitas Brawijaya, Malang, Indonesia, FATTAH Mochammad ,   Universitas Brawijaya, Fisheries Agribusiness Study Program, Fisheries Socioeconomic Department, Faculty of Fisheries and Marine Sciences, Universitas Brawijaya, Malang, Indonesia, HARAHAB Nuddin ,   Universitas Brawijaya, Fisheries Agribusiness Study Program, Fisheries Socioeconomic Department, Faculty of Fisheries and Marine Sciences, Malang, Universitas Brawijaya, Indonesia, KUSUMAWATI Andriani ,   Universitas Brawijaya, Business Administration Study Program, Universitas Brawijaya, Malang, Indonesia
Published: April 2023

Explanation of the purpose and objectives of the study (2-3 lines). Mangrove ecosystems perform biological and socioeconomic functions. Mangrove environments can be ecotourism destinations. This study analyzes mangrove potential to determine typical mangrove ecotourism attractions and strengthen the branding and marketing of mangrove ecotourism destination on the Tamban coast of Malang Regency, Indonesia. Explanation of the working methodology and the materials used (2-3 lines). Local management and communities validate mangrove potential field observations. GIS with Sentinel-2 and NDVI approach was used to analyze tides and satellite imaging data on mangrove thickness, density, and area. Analysis of mangrove potential in ArcMap utilizing five parameters: thickness, density, kind, biota, and tides. Four density classes were created using satellite imagery: non-mangroves, rare mangroves, moderate mangroves, and tight mangroves. Presentation and analysis of the obtained results (2-4 lines). The results showed that the Tamban coast mangrove area has a moderate ecotourism potential (potential value = 2.250), so it could be developed into mangrove ecotourism through conservation and limited utilization activities through marine ecotourism to provide economic, ecological, and social incentives. Mangrove ecotourism features that attract tourists and strengthen branding and marketing of this location include mangrove tourism education, canoeing, camping, spot photography, beach attractiveness, bird and violin crab biodiversity. The conclusions obtained following the application of the study (2-3 lines). Mangrove ecosystem on the Tamban coast has a high potential for conservation and marine ecotourism in order to provide economic incentives, also ecological and social benefits. The richness and distinctiveness of Tamban's mangrove ecotourism potential and attractions promotes the GPMC branding as a typical mangrove ecotourism.
Carotenoids and carotenes in the fruits of Cucurbita maxima, C. moschata and i>C. pepo under the conditions of Northwestern Russia
Authors: Piskunova T. M. , Shelenga T. V. , Ozersky P. V. , Solovyeva A. E.
Published: April 2023

Cucurbits are among the most valuable vegetable crops widely used for food all over the world, being an important source of carotenoids and carotenes, biologically active substances with antioxidant and other types of activity. Their content largely depends on the Cucurbita species and varietal features. The Cucurbita collection of the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) contains more than 3,000 accessions of five cultivated Cucurbita spp. and serves as the most important source of source material for developing new cultivars in order to expand the range of functional food products. The present research was aimed at studying the content of carotenoids and carotenes in the fruits of Cucurbita maxima Duch., C. pepo L. And C. moschata Duch. ex Poir. grown in Northwestern Russia, which is characterized by a short growing season and a low sum of active temperatures. The performed study revealed significant differences between the Cucurbita species and cultivars in terms of the content of carotenoids, total carotenes and β-carotene. In contrast to C. pepo, the accessions of C. maxima and C. Moschata were characterized by a wide range of variation of these characters. A statistically significant effect of the flesh and fruit skin color on the content of carotenoids, carotenes and β-carotene in them was observed (p < 0.001). The minimum amount of carotenoids, carotenes and β-carotene was found in the fruits with light yellow flesh, and the maximum in those with dark orange flesh. Cucurbit fruits with red skin accumulated more target compounds in contrast to the fruits with white skin. The identified Cucurbita accessions with high content of carotenes and carotenoids can be used as valuable source material for breeding cultivars with improved biochemical composition, which can broaden the range of functional food products when grown in the regions with unfavorable conditions for the production of this crop.
Influence of allelic polymorphism in the 3’ untranslated region of the StTCP23 gene on the tolerance of potato cultivars to the potato spindle tuber viroid
Authors: Mironenko N. V. , Kochetov A. V. , Afanasenko O. S.
Published: April 2023

Background. It is known that the pathological phenotype of potato plants can be mediated by complementary interactions between the genomic RNA of PSTVd and mRNA of some regulatory genes, which consequently lead to RNA interference, the synthesis of small interfering RNAs (vd-sRNA PSTVd), and impaired morphogenesis. At the same time, symptoms caused by the viroid may vary in different potato cultivars. Here we predict the interactions between the 3’ UTRs of various alleles of the StTCP23 transcription factor gene and the complementary regions in PSTVd genomic RNA.Materials and methods. We selected eight commercial potato cultivars with different symptoms of viroid infection and disease. For each cultivar, six clones of each cDNA amplicon of StTCP23 with a 3’ UTR were identified, and the allelic compositions of the target regions within their 3’ UTRs were characterized.Results. In total, 11 types of alleles of the 3’ UTR StTCP23 segment complementary to the vd-sRNA PSTVd were identified. Cultivars with the A allele (‘Gala’, ‘Colomba’, ‘Favorit’, and ‘Fioletovy’) identical to the reference genome or a high dose of the C allele with a deletion of four nucleotides (cv. ‘Impala’) were characterized by high susceptibility already at the primary (firstyear) infection with the PSTVd. Cvs. ‘Krepysh’, ‘Labadia’ and ‘Riviera’, classified as tolerant during primary inoculation, on the contrary, were characterized by the absence of the A allele and the presence of cultivar-specific mutant alleles.Conclusion. A high degree of polymorphism in the target site (3’ UTR region) of StTCP23 indicates a possible selection pressure on this locus. It can be assumed that cultivars with shorter alleles, which have fewer bases complementary to vd-sRNA in hypothetical duplexes and therefore less likely to induce target gene silencing, are more tolerant to the PSTVd upon primary viroid infection.
Molecular genetic diversity of flax cultivars (Linum usitatissimum l.) represented in the State Register for Selection Achievements of the Russian Federation
Authors: Bazanov T. A. , Uschapovsky I. V. , Loginova N. N. , Smirnova E. V. , Mikhailova P. D.
Published: April 2023

Background. When researching crop genetic diversity, including flax species, molecular markers are used to identify cultivars, establish phylogenetic relationships among them and select valuable genotypes and sources of useful traits. One of the effective ways to solve these tasks is the use of SSR markers, as a molecular method. The aim of this work was to study the molecular genetic polymorphism of modern flax cultivars listed in the State Register for Selection Achievements of the Russian Federation, find out their phylogenetic relationships and develop a version of their genetic certification.Materials and methods. The materials for the research were 82 flax cultivars (60 cultivars of fiber flax and 22 of oilseed flax) and 3 ancient landraces. Genetic analysis was carried out using the PCR method with a set of 11 SSR markers labeled with fluorescent dyes, followed by the detection of products on the genetic analyzer.Results. The study of the cultivars revealed 50 alleles at 11 loci, with the number of alleles per locus ranging from 2 to 10, averaged to 4.55 alleles per locus. Each flax sample contained a unique set of alleles.Conclusion. The resulting SSR database made it possible to develop genetic certificates for each cultivar in the form of an alphanumeric code. A cluster analysis was also carried out and a dendrogram of genetic similarity was constructed. The identified sib relationships among the cultivars confirmed the information about their origin.
Analysis of resistance to stem rust and identification of Sr genes in introgressive lines of spring bread wheat
Authors: Baranova O. A. , Sibikeev S. N. , Konkova E. A.
Published: April 2023

Background. Due to the increase in the harmfulness of wheat stem rust (Puccinia graminis f. sp. tritici Erikss. & E. Henn.) in the Volga region, and the likelihood of the spread of the aggressive Ug99 race, an assessment of the genetic diversity of wheat breeding lines and identification of effective Sr genes are of fundamental importance.Materials and methods. Ninety spring bread wheat introgressive lines with stem rust resistance, developed at the Federal Center of Agriculture Research of the South-East Region, were analyzed. Molecular markers were used to identify resistance genes: Sr24/Lr24, Sr25/Lr19, Sr26, Sr28, Sr31/Lr26, Sr32, Sr36, Sr38/Lr37, Sr39 and Sr57/Lr34. The analysis of plants for resistance was carried out according to standard methods; the Stakman scale was applied to determine the type of reaction.Results. The genes Sr31/Lr26, Sr25/Lr19, Sr57/Lr34, Sr38/Lr37 and Sr39/Lr35 were identified in the analyzed breeding lines. Sr25 was found in 51 lines (56,7% of samples), Sr31 in 41 lines (45.6%), Sr57/Lr34 in 5 lines, Sr38 in 10 lines and Sr39 in one line. Combinations of resistance genes were identified: Sr31+Sr25 in 28 lines (31.1%), Sr25+Sr38 in 5 lines, and Sr25+Sr39 in one line. The Sr24/Lr24, Sr26, Sr28, Sr32 and Sr36 genes were not identified.Conclusion. As a result, promising highly resistant introgressive wheat lines with promising combinations of Sr31+Sr25, Sr25+Sr38 and Sr25+Sr39 genes were identified. They can be used in Russian breeding programs for immunity.
The collection of oat genetic resources held by VIr as a source of information on the history of cultivation and taxonomy of the genus, and breeding trends (a review)
Authors: Loskutov I. G. , Blinova E. V. , Gnutikov A. A.
Published: April 2023

Oat is one of the leading cereals cultivated in the world and in Russia; it has an important fodder and nutritional value. To preserve the entire crop agrobiodiversity worldwide, there is a network of genebanks that hold more than 200,000 oat accessions. International and national genebanks are located in all the world’s countries, but one of the largest oat collections is located in Russia.The global collection of the genus Avena L. (Oats) at the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) is one of the largest worldwide and consists of over 13,000 accessions. The collection preserves and maintains live accessions of all cultivated oat species: A. sativa L., A. byzantina K. Koch, A. strigosa Schreb. and A. abyssinica Hochst., landraces, breeding lines, spring and winter forms, covered and naked genotypes, and all geographic diversity of 22 wild Avena spp. from 50 countries. This review provides historical background of the collection of cultivated and wild oat species, and who were the main donors of these holdings. The taxonomic system of the genus is briefly presented, which is used as a tool for efficient work and guaranteed safe preservation of accessions. Most of the cultivars developed in Russia have in their pedigree accessions obtained from the global collection of VIR. The passport database contains detailed information about all accessions of the collection, which makes it possible to improve the work with the oat collection, including safe preservation of accessions and their effective evaluation and use as source material for breeding in the leading breeding centers of Russia.Thus, the global oat collection at VIR has factual and potential value for the sustainable development of environmentally friendly agriculture, efficient processing of agricultural products, and production of safe and high-quality food products, including functional foods.