bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Latent Profile of Parents’ Emotion Dysregulation and the Predictive Factors: Differences in Children’s Executive Function
Authors:   Korean Academy Welfare Counselling, Jo Hyun Ji , Heo Moo Nyung
Published: March 2024

The purpose of this study is to classify the latent profiles of parents’ emotion dysregulation, to verify the effects of their self-esteem and subjective happiness as the predictors and to identify the differences in children’s executive function by these latent profiles. The subjects of this study were 595 parents and children who participated in the 13th Panel Study of Korea Children. The data were analyzed by latent profile analysis(LPA), analysis of variance, and multinomial logistic regression analysis using Mpuls 8.9 and SPSS 23.0. Major findings are as following. First, there were three different latent profiles, named Low-risk group(25.9%), Mid-risk group(53.4%) and High-risk group(20.7%) were found. Second, there were significant differences in children’s executive function by the latent profiles. Low-risk group had the lowest score for the executive function, and there was no significant difference between Mid-risk and High-risk group. Third, self-esteem and subjective happiness of parents had a significant effect on the classification of the latent profiles. These results showed that parent’s emotion dysregulation can cause children’s executive function by classifying the latent profiles of parents’ emotion dysregulation and examining the differences in children’s executive function between the profiles. Finally, based on these findings, we discuss the existing research and conclude with the implication that different interventions may be effective depending on the level of emotional dysregulation in order to address parental emotional distress.
Intraoperative imaging techniques for robotic-assisted partial nephrectomy: where do we stand?
Authors: Fasanella Daniela
Published: March 2024

Robot-assisted partial nephrectomy is currently the gold standard treatment for localized selected cT1 and cT2 renal tumors. This narrative review aims to analyze the technologies employed in this procedure to increase the precision and accuracy of the surgeon, in order to obtain adequate oncological radicality, negative surgical margins, and good preservation of renal function. In this scenario, new technologies are developing, from three-dimensional reconstructions to artificial intelligence up to the new concept of metaverse.
Fortifying Life Skills and Family Guardianship at the “KAMPUS BUNDA” Literacy Hub
Authors: Saputri Yulian Zhafirah Aji , Zain Kurnia Salsabila , Mubarokah Kismi , Suryawijaya Tito Wira Eka , Rahmadani Aulia Fajrin , Nurlaely Kharisma
Published: March 2024

Inisiatif "KAMPUS BUNDA" di Desa Sekayu bertujuan untuk menyediakan pendidikan kesehatan reproduksi dan seksual yang komprehensif bagi perempuan dan ibu, mengatasi masalah-masalah kompleks, dan menekankan pengawasan orang tua serta perlindungan dari ancaman digital. Dengan rencana implementasi selama tiga tahun dan dipandu oleh proyeksi kegiatan, program ini menunjukkan adaptabilitas terhadap kebutuhan masyarakat. Menggunakan pendekatan kualitatif dengan metode Double Diamond Design Thinking, implementasi mencakup identifikasi kebutuhan masyarakat, observasi lapangan, dan keterlibatan pemangku kepentingan. Kurikulum mencakup berbagai aspek kehidupan dengan menggunakan berbagai metode pembelajaran. Hasil program meliputi buku pengembangan keterampilan lunak bersertifikat, ringkasan eksekutif, dan dokumentasi yang disebarluaskan melalui media sosial. Hasil tambahan mencakup kurikulum bersertifikat IPR, artikel ilmiah, publikasi media massa, modul/panduan pembelajaran, dan video pendidikan, menunjukkan komitmen untuk mendukung inisiatif berkelanjutan dan berdampak di Desa Sekayu.Kata Kunci: Pengawasan Orang Tua, Remaja, Implementasi, Double Diamond The "KAMPUS BUNDA" initiative in Sekayu Village aims to provide comprehensive reproductive and sexual health education for women and mothers, addressing complex problems and emphasizing parental supervision and protection against digital threats. Structured with a three-year implementation plan and guided by activity projections, the program exhibits adaptability to community needs. Employing a qualitative approach with the Double Diamond Design Thinking method, the implementation includes identifying community needs, field observations, and stakeholder engagement. The curriculum covers diverse life aspects, using varied learning methods. Program outputs include a certified soft skills development book, an executive summary, and disseminated documentation through social media. Additional outcomes feature an IPR-certified curriculum, scientific articles, mass media publications, learning modules/manuals, and educational videos, illustrating a commitment to fostering a sustainable and impactful initiative in Sekayu Village.
MEMPENGARUHI ONLINE PURCHASE INTENTION DENGAN TRUST SEBAGAI VARIABEL INTERVENING PADA PELANGGAN MARKETPLACE DI BATAM
Authors: Zoy Beils  , Wisnu Yuwono
Published: March 2024

Secara global, terjadi kecenderungan meningkat dalam kegiatan belanja secara online, yang dianggap sebagai preferensi kritis karena jangkauan internet yang luas. Penggunaan internet secara global juga terus meningkat selama dua decade terakhir. Pada tahun 2019, dari 7,676 miliar penduduk, 4,388 miliar orang menggunakan internet, di mana 3,484 miliar di antaranya adalah pengguna media sosial aktif dan 3,256 miliar menggunakan internet melalui telepon seluler (Kemp, 2019). Meskipun pertumbuhan di seluruh dunia dalam penggunaan internet dan belanja online, di beberapa negara, masih ada pelanggan yang enggan berbelanja online karena kurangnya kepercayaan dan risiko yang dirasakan. Di sisi lain, faktor motivasi untuk belanja online termasuk penghematan waktu, diskon harga, kenyamanan dan harga yang kompetitif. Risiko yang dirasakan adalah masalah yang signifikan dalam belanja online karena pengaruh langsungnya terhadap sikap dan perilaku niat untuk membeli. Penelitian yang digunakan dalam penelitian ini adalah konsumen yang berbelanja barang-barang secara online di marketplace Shopee dan Tokopedia sebagai platform yang paling banyak dikunjungi konsumen di Indonesia. Sebagai populasinya adalah semua konsumen pembeli online pada marketplace di kota Batam. Penelitian dilakukan dengan menyebarkan kuesioner pada 350 responden. Hasil pengujian menunjukkan bahwa terdapat pengaruh signifikan brand image pada trust. Citra merek berpengaruh pada kepercayaan pelanggan pada marketplace. Namun tidak terdapat pengaruh signifikan E-WoM pada trust. Terdapat pengaruh signifikan service quality, website quality, price perception pada trust.  Terdapat pengaruh signifikan dari trust pada online purchase intention serta terdapat pengaruh signifikan brand image pada online purchase intention dengan trust sebagai variabel mediasi.
 Kata Kunci: Brand Image, E-WoM, Service Quality, Website Quality , Price Perception, Trust, Online Purchase Intention dan Marketplace
ANALISA KOMPETENSI KARYAWAN SEBAGAI VARIABEL MODERASI ANTARA KNOWLEDGE SHARING DAN EFEKTIVITAS PELATIHAN TERHADAP KINERJA KARYAWAN
Authors: Lestari Irena Sri , Rahmawati Rini
Published: March 2024

The aim of this study is to discover and evaluate the impacts of knowledge transfer and training efficacy on employee performance, with employee competency serving as a moderator. 40 employees from the Bank Kalsel Amuntai Branch took part in this survey as responders. The analytical application used is called SmartPLS. The study's conclusions show that training effectiveness and information sharing both have positive and substantial influence on worker performance. The impacts of information exchange and training efficacy on performance are also moderated by employee competency
Critical minerals from primary and secondary geological sources, and their recovery - extraction with Indian examples
Authors: Raju R. Dhana
Published: March 2024

Critical minerals have a global demand due to their important/strategic applications in many high-tech industries, such as the green-renewable energy, electricals and electronics, telecommunications, superalloys, nuclear, space, artificial intelligence, defense, etc. The list of CMs is dynamic and depends upon the availability and perspective of each country, based upon the issues like geological scarcity, geopolitical considerations, trade policy, problems in supply chain, and other factors. CMs can be broadly grouped into: (i) Rare Earth Element (REEs); (ii) battery metals (Li, Co, Ni, Mn, Graphite); (iii) alloy metals (Ti, V, Cr, Ni, Nb-Ta, Sn); (iv) nuclear metals (U, Th, Zr-Hf, Be); (v) precious metals (Au, Ag, platinum group metals); (vi) toxic metals (Pb, As), and (vii) fertilizer commodities (phosphate, potash). Geologically, they are recoverable from diverse materials of rocks, ore minerals, mineral concentrate, sands, etc., with their sources being either primary or secondary. The primary sources for CMs were deposited during period(s) of mineralization in a wide variety of rock types. When such primary sources of rocks and ore deposits (constitute a provenance) were subjected to alteration, due to weathering or other surficial processes resulting from descending surface waters, it gave rise to the secondary sources of CMs like the supergene deposits of laterite, overburden, conglomerate, and placers of different types. Indian examples of the primary and secondary geological sources for CMs and their recovery and extraction are presented.
Management strategy for virus-induced inflammation in COVID-19. Results of a multicenter, adaptive, randomized, double-blind, placebo-controlled study in outpatients
Authors:   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Kalyuzhin O.V. , Baranova A. ,   George Mason University, Fairfax, Virginia, USA, Bagaeva M.I. ,   JSC Valenta Pharm Pharmaceutical Company, Moscow, Russian Federation
Published: March 2024

SARS-CoV-2 infection is associated with increased production of pro-inflammatory cytokines and chemokines, followed by the development of immunothrombosis and hypercoagulation, which are important determinants of illness severity, survival prediction and long-term post-infection sequelae. More than that, thrombotic events may even develop in non-severe COVID-19 cases, including following specific thromboprophylaxis administered concurrently with the infection treatment. Therefore, preventing excess inflammation as a cause of subsequent micro- and macro-vascular thrombotic disease is becoming an increasingly important issue today. The objective of the multi-center, adaptive, randomized, double-blind, placebo-controlled trial was to evaluate the efficacy and safety of Aterixen® (ХС221GI) in patients with mild COVID-19. Patients and methods. A total of 274 subjects (age range, 18 to 75 years) with mild COVID-19 were enrolled. The study included 3 stages: screening, drug administration, and follow-up activities. The maximum overall duration of subject participation was 32 days. The subjects were randomized into 2 similar groups receiving Aterixen® (100 mg tablets administered at a dose of 1 tablet twice daily for a total of 14 days) or placebo matching the study drug in addition to the standard treatment in line with the Temporary Guidelines of the Russian Ministry of Health for the prevention, diagnosis and treatment of COVID-19. Results. The ITT and PP efficacy analyses based on the composite primary endpoint showed that Aterixen® was superior to the placebo and had a favorable safety profile. Furthermore, the number of pneumonia cases was nearly 80% lower in Ateriхen® treated subjects who required admission to hospital. Key words: COVID-19, new coronavirus infection, cytokine hyperproduction, immunothrombosis, preventive anti-inflammatory therapy, Aterixen®, ХС221GI
Virus-related liver cirrhosis: clinical profile of a patient, thanatogenesis, and pathomorphology
Authors:   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russian Federation, Esaulenko E.V. ,   Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, Saint Petersburg, Russian Federation, Novak K.E. ,   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russian Federation, Dzemova A.A. ,   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russian Federation,   Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, Saint Petersburg, Russian Federation, Lyalina L.V. ,   Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, Saint Petersburg, Russian Federation, Tsinzerling V.A. ,   S.P.Botkin Clinical Hospital of Infectious Diseases, Saint Petersburg, Russian Federation, Fedunyak I.P. ,   S.P.Botkin Clinical Hospital of Infectious Diseases, Saint Petersburg, Russian Federation
Published: March 2024

Objective. To analyze the profile of a patient with virus-related liver cirrhosis examined at different levels of healthcare, to identify the main causes of death, and describe morphological changes in liver tissue. Patients and methods. This study included 921 patients with chronic viral hepatitis (CVH) treated in day hospitals, 844 patients treated in inpatient facilities, and 455 CVH patients who died. We analyzed autopsy results of 97 patients with clinical signs of liver cirrhosis and described morphological characteristics of liver tissue depending on the Child–Turcotte–Pugh score. Results. Chronic hepatitis C is the most prevalent form of hepatitis in both inpatient and outpatient units. The highest incidence of latent hepatitis B was observed among inpatients. The majority of outpatients with virus-related liver cirrhosis were employable (or employed), socially adapted, not addicted to alcohol, and had compensated disease (class A in 97%) with minimal clinical manifestations, and were motivated for treatment and examination. The mean age of inpatients was 50 years; 100% of them had some comorbidities; 90% of them had subcompensated or decompensated cirrhosis; 60% of them systematically abused alcohol. Conclusion. The majority of deceased patients were employable, abused alcohol, and were not systematically followed-up by a specialist. Almost one-third of them (30%) had subcompensated disease and incomplete cirrhotic transformation of hepatic tissue; they died due to other reasons. This affects the course of chronic virus-related hepatitis and comorbidities and necessitates the creation of integrated comprehensive models of healthcare. Key words: virus-related liver cirrhosis, comorbidity, morphological examination, latent hepatitis, chronic viral hepatitis
The experience of real practice antiviral therapy of chronic hepatitis D in the Republic of Crimea
Authors:   S.I.Georgievsky Medical Academy of the V.I.Vernadsky Crimean Federal University, Simferopol, Russian Federation, Rymarenko N.V. , Achkasova T.A. ,   S.I.Georgievsky Medical Academy of the V.I.Vernadsky Crimean Federal University, Simferopol, Russian Federation
Published: March 2024

Objective. The analysis of the results of antiviral therapy of chronic hepatitis D (HDV) in real practice using bulevirtide, an inhibitor of the entry of hepatitis B and D viruses (HDV) into the hepatocyte. Patients and methods. Intermediate treatment results were studied in 6 patients with HDV, including 3 patients with compensated cirrhosis who received bulevirtide in combination with pegylated interferon-α for 48 weeks, as well as in 3 patients who continued treatment (in combination therapy or monotherapy) for up to 60–64 weeks. Results. After 48 weeks of combination therapy, the HDV RNA level decreased from 6.5 log10 to 1.0 log10 ( p = 0.015), the median decrease was 3.4 log10, the frequency of virological response was 83%, and aviremia was 50%. Virological efficacy increased with treatment. In 3 patients, an increase in the initially normal level of alanine aminotransferase (ALT) associated with the use of interferon was noted, followed by a decrease or normalization; in 2 patients with initially moderate and high liver activity, ALT levels decreased by 35 and 354 U/l, respectively. Virological and biochemical response was maintained in all 3 patients who continued treatment up to 60–64 weeks, including aviremia in 1 patient. No serious adverse events, cases of withdrawal of treatment or deterioration of liver function in cirrhosis have been reported. Conclusion. The analysis of the intermediate results of CHD treatment in real practice has demonstrated the effectiveness, safety and good tolerability of bulevirtide, including at the stage of compensated liver cirrhosis. Further study of optimal treatment regimens is needed to achieve treatment goals and improve the prognosis of the disease. Key words: bulevirtide, chronic hepatitis D
The role of bacteria of the genus Desulfovibrio sp. in human pathology
Authors:   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Ploskireva A.A. , Kulikova N.G. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Bityumina L.A. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Gorelov A.V. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation,   A.I.Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation
Published: March 2024

Bacteria of the genus Desulfovibrio sp. They are widespread in the environment – they are found in soil, wastewater, bottom sediments. The effect of these microorganisms on the development of pathological conditions in humans has not been fully established. Bacteria of the genus Desulfovibrio sp., gram-negative, curved microorganisms,non-spore – forming, slow-growing, anaerobic. Objective. Identification of pathogenetic features of the effect of sulfate-reducing bacteria of the genus Desulfovibrio sp. on the human. Patients and methods.167 patients who signed a voluntary informed consent was conducted among patients who applied to the Federal State Budgetary Institution "Central Research Institute of Epidemiology" for an examination of intestinal microbiocenosis. Microbiological examination of the biomaterial was carried out using traditional microbiological methods. The following blood parameters were used to assess iron metabolism in the body: hemoglobin, serum iron, ferritin, transferrin, unsaturated iron binding capacity of serum and the percentage of transferrin saturation with iron. Statistical data analysis was performed using standard descriptive statistics methods using Excel (Microsoft Corporation, 2019, USA). The statistical significance of the differences in the compared indicators was assessed using the Student's t-test the significance level of p < 0.05 (t > 2). Results. Bacteria of the genus Desulfovibrio sp. were found in 66 patients (39.5%). In the group of patients whose examination revealed bacteria of the genus Desulfovibrio sp., the number of people with anemia was 16, without anemia was 50. Among patients with the absence of bacteria of the genus Desulfovibrio sp. in the microbiocenosis. laboratory-confirmed iron metabolism disorder with the development of anemia was detected in 11 people, the absence of anemia in 90. The calculation of the odds ratio showed that the risk of anemia increases 2.6 times [95% CI 1.13–6.08] in the presence of bacteria of the genus Desulfovibrio sp in the intestine. Conclusion. It can be assumed that bacteria of the genus Desulfovibrio sp. is one of the etiological factor of the development of iron deficiency anemia in humans. Key words: microbiocenosis, iron deficiency anemia, Desulfovibrio desulfuricans
Islamic Boarding School And The Hardiness Of Santri: Collaboration Of Islamic Religious Teachers And Guidance And Counseling At Pesantren
Authors: Karimah Ummah , Ayuhan Ayuhan , Yunus Ahmad , Zulfikri Alif
Published: March 2024

Islamic Boarding School And The Hardiness Of Santri: Collaboration Of Islamic Religious Teachers And Guidance And Counseling At Pesantren. This study aims to analyze and describe the form of implementation of the collaboration between PAI teachers and BK teachers in developing the hardiness of students at Darul Arqam Sawangan Islamic Boarding School. Hardiness is a personality that must be owned by students in carrying out life in Islamic boarding schools when facing the problems they face. The importance of doing this research because there are still minimal guidance and counseling services that are carried out and can be done in collaboration with PAI teachers in islamic boarding school. This research method used a qualitative method with a descriptive approach. The data collection techniques through three methods, including: interviews, documentation, observation, and field notes (documentation). The data analysis technique used the stages of data reduction, data presentation, and conclusions. The results of this study indicated that the form of implementation of the collaboration between PAI teachers and BK teachers in developing the hardiness of students by sharing their respective tasks, such as PAI teachers who provided material to become hardiness students during teaching and learning activities and provide information related to the progress of students. Whereas, BK teachers run the BK program through personal field services for students with classical guidance techniques and group counseling. This study has limitations due to the background of students is various, this does not rule out the possibility that the level of toughness of students is different and in providing material about hardiness and it cannot be expected that all students will experience an increase.
Keywords: PAI Teachers; BK Teachers; Hardiness; Islamic Boarding Schools; Santri
Analysis of International Relations Theory Toward the Prospective Foreign Policy in the Vision and Mission of Indonesian Presidential Candidates 2024
Authors: Sally Novian Uticha , Orwela Citra
Published: March 2024

As the national election in Indonesia is drawing close, the political competition done by each of presidential and vice-presidential candidates is getting massive. The year 2023 becomes pivotal for the candidates to show case their potential and attention to the significant issues. In the same year, a lot has happened in the international sphere that influences Indonesian local politics. This article will seek to analyze the political communication used by Indonesian presidential and vice-presidential candidates in their campaign in responding global issues. The research approach used in this research is qualitative approach using comparative analysis techniques. The type of research is library research, in which datum will be collected from vision and mission of presidential candidates. The result shown that all Indonesian presidential candidates have made some agendas pertaining eco-global, cooperation and competition in the international realm.
Three-Dimensional Osseointegration Patterns of Cementless Femoral Stems
Authors: Schwarz Gilbert M. , Synek Alexander , Senck Sascha , Kandathil Sam A. , Holzleitner Martin , Trieb Klemens , Huber Stephanie , Pahr Dieter , Hofstaetter Jochen G. , Hirtler Lena
Published: March 2024

Background:

Osseointegration is essential for the long-term survival of cementless femoral stems and is dependent on periprosthetic bone quality and correct implantation technique. The aim of this study was to evaluate the 3-dimensional long-term fixation patterns of, and bone microarchitecture around, cementless hip stems.

Methods:

Four specimens with varying degrees of bone quality and fixation characteristics from body donors who had received Alloclassic Zweymüller hip stems during their lifetime (mean time in situ at the time of death: 12.73 years) were evaluated with use of radiographs, high-resolution computed tomography (CT) scans, and hard-tissue histology. The CT voxel size was 85 µm, and the following parameters were calculated: total bone volume, total bone volume fraction, trabecular bone volume, trabecular bone volume fraction, cortical bone volume, cortical bone volume fraction, and cortical thickness. Bone-implant contact and canal fill index values for each Gruen zone of the specimens were calculated with use of histological samples.

Results:

Femoral stems with apparently good cortical contact on clinical radiographs showed higher values for cortical bone volume, trabecular bone volume, and cortical thickness in the high-resolution CT analysis than femoral stems with apparently weak cortical contact on clinical radiographs. Based on the histological evaluation, the mean bone-implant contact ranged from 22.94% to 57.24% and the mean canal fill index ranged from 52.33% to 69.67% among the specimens.

Conclusions:

This study demonstrated different osseointegration patterns of cementless femoral stems on the basis of radiographs, high-resolution CT scans, and histological evaluation. Femora with high cortical bone volume and cortical thickness were associated with higher canal fill indices, whereas femora with low cortical bone volume and cortical thickness had lower canal fill indices and showed a characteristic corner-anchorage pattern.

Clinical Relevance:

Osseointegration patterns and thus the long-term survival of cementless femoral stems are dependent on cortical bone volume and cortical thickness.
The Hawkins Sign of the Talus
Authors: Griffin Jarod T. , Landy David C. , Mechas Charles A. , Nazal Mark R. , Foster Jeffrey A. , Moghadamian Eric S. , Srinath Arjun , Aneja Arun
Published: March 2024

Background:

Osteonecrosis is a complication of talar neck fractures associated with chronic pain and poor functional outcomes. The Hawkins sign, the radiographic presence of subchondral lucency seen in the talar dome 6 to 8 weeks after trauma, is a strong predictor of preserved talar vascularity. This study sought to assess the accuracy of the Hawkins sign in a contemporary cohort and assess factors associated with inaccuracy.

Methods:

A retrospective review of talar neck fractures at a level-I trauma center from 2008 to 2016 was conducted. Both the Hawkins sign and osteonecrosis were evaluated on radiographs. The Hawkins sign was determined on the basis of radiographs taken approximately 6 to 8 weeks after injury, whereas osteonecrosis was determined based on radiographs taken throughout follow-up. The Hawkins sign accuracy was assessed using proportions with 95% confidence intervals (CIs), and associations were examined with Fisher exact testing.

Results:

In total, 105 talar neck fractures were identified. The Hawkins sign was observed in 21 tali, 3 (14% [95% CI, 3% to 36%]) of which later developed osteonecrosis. In the remaining 84 tali without a Hawkins sign, 32 (38% [95% CI, 28% to 49%]) developed osteonecrosis. Of the 3 tali that developed osteonecrosis following observation of the Hawkins sign, all were in patients who smoked.

Conclusions:

A positive Hawkins sign may not be a reliable predictor of preserved talar vascularity in all patients. We identified 3 patients with a positive Hawkins sign who developed osteonecrosis, all of whom were smokers. Factors impairing the restoration of microvascular blood supply to the talus may lead to osteonecrosis despite the presence of preserved macrovascular blood flow and an observed Hawkins sign. Further research is needed to understand the factors limiting Hawkins sign accuracy.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Evaluasi Aplikasi E-Visum di Rumah Sakit Muhammadiyah Lamongan Menggunakan Metode HOT-Fit
Authors: Novitasari Diah Ayu , Yuliani Resta Dwi
Published: March 2024

Visum et Repertum (Visum) merupakan alat bukti laporan tertulis yang digunakan dalam persidangan oleh pihak yang memiliki wewenang seperti penyidik. Rumah Sakit Muhammadiyah Lamongan memiliki aplikasi elektronik visum (e-visum). Tujuan penelitian ini adalah evaluasi e-visum dengan menggunakan metode HOT-Fit. Jenis penelitian kualitatif dengan sampel 9 dokter IGD dan 1 dokter penangung jawab forensik. Hasil penelitian berdasarkan aspek human petugas melakukan double entry pada aplikasi karena belum terintegrasi dengan telegram, berdasarkan aspek organization perlu dilakukan evaluasi dan pengawasan, berdasarkan aspek technology sudah sesuai dengan indikator sistem, berdasarkan net benefit e-visum bermanfaat bagi user di Rumah Sakit Muhammadiyah Lamongan karena dapat meningkatkan pelayanan dan mengurangi tingkat kesalahan.

Kata kunci : e-visum, HOT-Fit, evaluasi
Analisis sistem surveilans bencana banjir di Puskesmas Kanor Kabupaten Bojonegoro
Authors: Finazis Rekha
Published: March 2024

Indonesia merupakan negara kepulauan rawan terhadap bencana.Data dari BNPBmenyebutkan bahwa di tahun 2016 pada bulan januari hingga juni terdapat sebanyak 1.287kejadian bencana. Pada juli tahun 2016, bencana hidrometeorologi khususnya banjir masihmendominasi di Indonesia. Kabupaten Bojonegoro menjadi salah satu daerah yang rawanterhadap bencana banjir, dan Puskesmas Kanor merupakan salah satu puskesmas yang berpotensiterkena dampak luapan sungai Bengawan Solo. Oleh karena itu, perlu dilakukan surveilans pra,saat dan pasca bencana untuk mengantisipasi dan menanggulangi bencana banjir di wilayahtersebut.Tujuan yang ingin dicapai dalam penelitian ini adalah mengembangkan basis datasurveilans bencana banjir di Puskesmas Kanor di Kabupaten Bojonegoro. Metode penelitian yang dilakukan adalah penelitian pengembangan basis data dantermasuk penelitian action research. Unit analisis penelitian ini adlah unit desa di wilayah kerjaPuskesmas Kanor. Teknik pengumpulan data dengan wawancara mendalam kepada petugas kesehatan. Adapun kerangka operasional dalam penelitian ini dimulai dari analisis sistem surveilans yang sedang berjalan, analisis kebutuhan data dan infromasi, pengembangan basisdata dan uji coba.Hasil penelitian menunjukkan bahwa pada sistem surveilans yang sedang berjalanditemukan masalah pada komponen input, proses dan output.Sehingga perlu adanya pengembangan Sistem Surveilans bencana banjir di Puskesmas Kanor Kabupaten Bojonegoro
Rethinking aid system narratives: The case for collaborative leadership
Authors: Timmins Nigel , Hallwright Joshua
Published: March 2024

Disasters—whether so called ‘natural’ disasters or conflict related crises—are a growing challenge. Their impacts have a profound impact on development outcomes since disasters at best mitigate against development gains, and more commonly lead to development losses, particularly for people living in poverty. Yet while disasters are often treated as exceptional events, they in fact highlight failures in our development pathways—and expose the humanitarian and development system as unfit to respond adequately to these challenges. This paper reflects on the ways of thinking and incentives that shape the behaviour that leads to the perpetuation of this siloed and reactionary system and argues that there is a need to re-frame disasters as contextual factors rather than exceptional events within the development framework. Additionally, there is a need to support leaders who collaborate, instead of working to achieve individual success for their department or institution, and to strengthen accountability to make the development and humanitarian system more effective in supporting disaster affected and at-risk communities.
Sedimentary record of historical seismicity in a small, southern Oregon lake
Authors: Morey Ann E. , Shapley Mark D. , Gavin Daniel G. , Nelson Alan R. , Goldfinger Chris
Published: March 2024

We compare event deposits from the historical portion of the sedimentary record from Lower Acorn Woman Lake, Oregon, to historical records of regional events to determine if the lake records Cascadia earthquakes. We use the sedimentological characteristics and x-Ray Fluorescence (XRF) provenance of disturbance deposits (labelled A-J) from the historical portion (post 1650 CE) of the record to discriminate between deposit types. We show that earthquake-triggered deposits can be differentiated from flood deposits, and Cascadia earthquakes deposits can be differentiated from other types of earthquake deposits. Event deposit J dates close to 1700 CE (1680-1780 CE) through multiple approaches, suggesting it was the result of shaking from the magnitude (M) 8.8-9.2 1700 CE Cascadia megathrust earthquake. Event deposits H and I are a complex sequence deposited in response to the ~M7.0 1873 CE Brookings earthquake. This earthquake has been previously interpreted to be an intraplate earthquake, is reinterpreted here as the result of an earthquake on a nearby crustal fault. Furthermore, the methods used have uncovered a previously unrecognized crustal earthquake deposit in the tail of deposit J, suggesting a stress relationship between Cascadia earthquakes and crustal earthquakes. These results not only demonstrate the usefulness of these methods to identify cryptic earthquake deposits and discriminate between subduction earthquake and other type of earthquake deposits in sediments from small, Cascadia lakes, but also suggest previously unknown relationships between subduction and crustal earthquakes in Cascadia.
Exploring traditional medicines used for bleeding control and termination of pregnancy among Suri People, South West Ethiopia, 2022:Mixed qualitative study design
Authors: Wale Alemnew , Kassie Aychew , Solomon Nahom , Girma Desalegn
Published: March 2024

Background: Traditional practices and remedies have been used to maintain health, prevent sickness, and/or treat it throughout human history. The treatment of severe bleeding, stopping pregnancies, and other gynecologic conditions have all been addressed by women using these techniques. Even though research has been done to understand more about these concerns, particularly in developing countries and in particular in our own country, they are still not adequately addressed. The purpose of this study was to learn more about the traditional treatments and remedies used by women in pastoralist communities in Residents of south Western Ethiopia.
Objective: To Assess and explore traditional medicines used for bleeding control and termination of pregnancy among Suri People, South West Ethiopia, 2022
Methods: An exploratory study was conducted at selected kebeles of Suri District, South West, Ethiopia from February 1 to August 30 /2022. Systematic random sampling and purposive sampling techinique was emplemneted for quantitative and qualitative study respectively.
Result: A total of 60 People participated in qualitative study and 350 women participated in the quantitative study, with making 100% response rate. The proportion of , abortion, and bleeding control were 38%, and 36% respectively. Blood tree(28%),Shawly tree(38%) and Sitch lady(34%) were used as bleeding control. The root of banana (15%), the root of maize (19%), Teteracycle with alcohol (14%), Quartum (17%), boiled alcohol (15%), and soot grass (20%), leave olive and salty soil were the most common traditional medicine used for termination of pregnancy.
Conclusion: Suri women primarily use the calendar method of family planning to prevent pregnancy. They also use various plants, alcohol, and drugs to interrupt pregnancy as well as blood and shawily tree to manage bleeding during ( heavy menstrual, abortion, and postpartum periods). To help people to use safe methods and avoid those that have a negative impact on mothers, it is imperative to learn more about the value of these traditional methods.
Efficient texture prediction for additive manufacturing
Authors: Liang Xiaohui , Zhu Jianing , Popovich Vera , Hermans M , Richardson Ian , Bos Cornelis
Published: March 2024

Microstructure features including grain morphology and texture are key factors in determining the properties of additively manufactured metallic components. In a digital twin of additive manufacturing, as it is still challenging to directly obtain microstructure features with sensors, microstructure control relies on the predictions from mechanistic models. However, available mechanistic models for texture prediction are too computationally expensive for digital twin applications. Here, we propose a cellular automata model, which is up to two orders-of-magnitude faster than traditional models. By adopting an exact temporal integration and a multi-level capture algorithm, a large time step can be employed without compromising the simulation accuracy. The proposed model is validated with a 316L steel case and three NiTi cases, where a good agreement is achieved between the simulations and the experiments. Our findings reveal the preferential orientations are selected by the vertical and the inclined temperature gradients from multi-pass temperature profiles, leading to different grain morphologies and textures. With a significant reduction in computational cost while maintaining accuracy, this approach marks a crucial step towards a practical implementation of digital twin for additive manufacturing.
The Effect of Bacteria on Uranium Sequestration Stability by Different Forms of Phosphorus
Authors: Tan Wen-fa , Deng Zhi-Wen , Lv Jun-wen , Tang Dong-shan , Li Jia-xiang , Pang Chao
Published: March 2024

Immobilization of uranium (VI) via uranium-phosphate (U-P) precipitation exhibits a great potential in remediation of uranium in contaminated environments. However, phosphorus as a vital element of bacteria, the decomposition, absorption and transformation of phosphorus may affect the stability of uranium with aging time. The main purpose of this work is to study the effect of bacteria on uranium sequestration mechanism and stability by different forms of phosphorus in a water sedimentary system. The results showed that addition of phosphate effectively enhanced uranium removal rate, with the highest removal rate of 99.84%. According to the X-Ray Diffraction (XRD), Scanning Electron Microscopy and Energy Dispersive Spectrometer (SEM-EDS) analyses, the fugitive positions of phosphorus and uranium elements remained essentially the same on the sediment surface, meanwhile the appearance of more pronounced phosphorus and uranium signal peaks confirmed the existence of U-P precipitates. X-ray Photoelectron Spectroscopy (XPS) analyses imply that hexavalent uranium and tetravalent uranium co-exist in the precipitate. Combined with BCR results, bacteria and phosphorushave a synergistic effect on uranium immobilization, although there will be a small part of uranium release due to the action of bacteria with the extension of time. Collectively, the results demonstrated that bacteria and phosphorus could effectively mediate U-P precipitates, realizing the transformation and immobilization of uranium from a transferable phase to a stable phase. The experimental findings could provide theoretical evidence for uranium immobilization in uranium-contaminated groundwater sediment.
Correlation between toxic organic acid fluctuations and neurodevelopment in patients with methylmalonic acidemia
Authors: LING I CHIH , Niu Dau-Ming , Yang Chia-Feng , Lee Cheng-Yu , Liang Sheng-Bin , Chen Yann-Jang
Published: March 2024

Background
Methylmalonic acidemia (MMA) is a rare autosomal recessive disorder, that causes multisystem damage by accumulating toxic metabolites. These metabolites, particularly affecting nerve cells, contribute to suboptimal neurodevelopment in MMA patients. While fluctuations in these toxic metabolites are common in MMA patients, their precise impact on neurodevelopment remains unclear.
Results
This study enrolled 20 MMA patients, comprising 14 methylmalonyl-CoA mutase (MMUT) type and 6 cobalamin (cbl) type. Diverse parameters were assessed, including methylmalonic acid (MA), methylcitric acid (MCA), propionylcarnitine (C3), acylcarnitine (C2), ammonia, glycine, and lactate. Cognitive function was evaluated using the Bayley-III and Wechsler intelligence scale, and brain imaging was conducted through magnetic resonance spectroscopy (MRS). The frequency and extent of fluctuations in toxic organic acids were computed based on blood test results. MMUT-type patients exhibited elevated levels of MA, MCA, C3, C3/C2 ratio and lactate, with more frequent and significant MA and C3 fluctuations than cbl-type patients. Brain imaging revealed central nervous system (CNS) demyelination in MMUT-type patients, while cbl-type patients displayed normal MRS results. Cbl-type patients exhibited significantly better neurocognitive outcomes, with higher scores in cognitive, motor, language, and social-emotional domains. A negative correlation was identified between the frequency of MA fluctuations and the developmental status of MMA patients.
Conclusion
Variances between MMUT-type and cbl-type MMA patients extend to neurocognitive outcomes, along with differences in frequency and magnitude of toxic organic acid fluctuations. MMA, particularly in MMUT-type patients, is associated with developmental delays and cognitive deficits, contrasting with more favorable outcomes in cbl-type patients due to treatment efficacy. Furthermore, a negative correlation was identified between the frequency of widely fluctuating MA and developmental conditions in MMA patients.
Observation of canalized phonon polaritons in a single-layer α-MoO3 flake
Authors: Wang Kai , Wang Kun , Long Hua , Xiong Langlang , Deng Nan , Wang Bing , Hu Guangwei , Lu Peixiang
Published: March 2024

The canalization effect of phonon polaritons (PhPs) shows highly directional, and diffraction-less propagation characteristics in van der Waals (vdW) materials, offering new opportunities to mold the light flow at nanoscale for near-field energy, information and thermal managements. Previously, canalized PhPs have only been experimentally realized in the hexagonal boron nitride metasurface, heterostructures of twisted α-phase molybdenum trioxide (α-MoO3) crystal flakes or the hybridized system. However, these systems typically have complex structures, and require strict operational conditions, such as fine structural parameters, a specific photonic magic angle or a doping level of graphene, for realizing polariton canalization with a modest performance. Here, we demonstrate the high-quality PhPs canalization in a single-layer natural α-MoO3 crystal flake. The canalized PhPs exhibit the highly directional, and diffraction-free propagation features, associated with lateral confinement ratio up to λ0/80 (where λ0 is the free-space wavelength of the incident laser). We believe this work is important to effectively manipulate PhPs in natural vdW materials, with potential applications in nanoimaging, directional energy transfer and enhanced nonlinearity at the deep subwavelength scale.
Association between Systolic Blood Pressure Variability and Incident Aortic Stenosis
Authors: Kim Hyun Jung , Kim Ji Eon , Jung Jae Seung , Kim Hee Jung , Son Ho Sung
Published: March 2024

This study investigated the potential link between blood pressure variability (BPV) and the incidence of aortic stenosis (AS) using Korean National Health Insurance Service data from 2002 to 2019. We collected annual systolic blood pressure variability (SBPV) measurements, consisting of three consecutive blood pressure readings each year over three years. The obtained SBPV data was divided into five quantiles, with the highest quintile representing high fluctuation of blood pressure. Analyzing 9,341,629 individuals with a mean age of 40.7 years, the study found 3,981 new AS diagnoses during an average 8.66-year follow-up. Independent predictors for AS included higher blood pressure levels and elevated systolic blood pressure variability (SBPV). The hazard ratios (HR) for different SBPV quintiles, compared to the reference (1st quintile), were as follows: 2nd quintile HR 1.09 (p = 0.18), 3rd quintile HR 1.13 (p = 0.04), 4th quintile HR 1.13 (p = 0.04), and 5th quintile HR 1.39 (p < 0.001). Our findings suggest that both hypertension and high fluctuations in SBP during consecutive visits are associated with an increased risk of incident AS. These results emphasize the importance of blood pressure management and stability in the prevention of AS.
CSE - A Automated Theorem Prover Based on Standard Contradiction Separation Dynamic Deduction
Authors: Cao Feng , Wang Jiafan , Xu Yang , Liu Jun , Yi Jianbing
Published: March 2024

Contradiction Separation Extension (CSE in short), an automated theorem prover for first-order logic without equality, which is based on a novel standard contradiction separation (S-CS) inference rule. Different from binary resolution or its refinements, the biggest difference and characteristic of S-CS rule is that each resolution step can handle multiple (two or more) clauses for synergized deduction. This paper mainly describes problem format conversion, clause set preprocessing, deduction framework, distinctive heuristic strategies, S-CS dynamic inference mechanism in CSE. CSE is evaluated through benchmarks and the deduction characteristics of this multi-clause dynamic deduction are demonstrated, e.g., FOF division problems of CASC-26, CASC-J9. In addition, the CASC-J9 is also tested by combined systems, which combine CSE and other prover (Prover9, Eprover, Vampire), and the combined systems is applied to test on the hard problems with rating of 1. Experimental results show the CSE shows a competitive performance and can play a role in first-order logic automated theorem proving.
TRIP13 regulates progression of gastric cancer through mediating ubiquitination modification of DDX21
Authors: Zhang Guanghui , Yang Rui , Wang Baiyan , Yan Qiujin , Zhao Peiyuan , Zhang Jiaming , Su Weiyu , Yang Lianhe , Cui Hongjuan
Published: March 2024

GC (Gastric cancer) is one of the most common malignant tumors, with over 95% of gastric cancer patients being adenocarcinoma and most gastric cancer patients having no obvious symptoms in the early stages. Therefore, finding biomarkers for early screening of gastric cancer and exploring new targets for gastric cancer treatment are urgent problems to be solved in the treatment of gastric cancer, it has important clinical significance in improving the survival rate of gastric cancer patients. The AAA + family ATPase thyroid hormone receptor interacting protein 13 (TRIP13) has been reported to play an important role in the development of various tumors, however, the biological function and mechanism of TRIP13 in gastric cancer are remain unclear. Here, our study confirms that TRIP13 is highly expressed in gastric cancer tissue samples, and that TRIP13 participates in the proliferation, migration, and invasion of gastric cancer cells. Mechanistically, our study confirms that TRIP13 directly interacts with DDX21 and stabilizes its expression by restraining its ubiquitination degradation, thereby promoting the progression of gastric cancer. Additionally, we found that histone deacetylase 1 (HDAC1) is an upstream factor of TRIP13, which could target the TRIP13 promoter region to promote the proliferation, migration, and invasion of gastric cancer cells. These results indicate that TRIP13 serve as a promising biomarker for the treatment of gastric cancer patients, and the HDAC1-TRIP13/DDX21 axis might provide solid theoretical basis for clinical treatment of gastric cancer patients.