bluuebunny/crossref_metadata_2025 huggingface dataset:
The Intertwining of Posttraumatic Stress Symptoms, Alcohol, Tobacco or Nicotine Use, and the COVID-19 Pandemic: A Systematic Review
Authors: Mengin Amaury C. , Rolling Julie , Porche Christelle , Durpoix Amaury , Lalanne Laurence
Published: November 2022

Background: Posttraumatic stress symptoms (PTSSs) and alcohol, tobacco, or nicotine use are frequently associated conditions. The COVID-19 pandemic has been a stressful situation globally and has worsened mental health conditions and addictions in the population. Our systematic review explores the links between PTSSs and (1) alcohol use and (2) tobacco or nicotine use during the COVID-19 pandemic. Methods: We searched the PubMed, PsycINFO, and Web of Science databases for studies published between January 2020 and 16 December 2021. We included studies published in English concerning adults or adolescents. Included articles dealt simultaneously with the COVID-19 pandemic, PTSSs, and alcohol, tobacco, or nicotine use. The reports included were cross-sectional, longitudinal, or cohort studies. We categorized the reports according to the population explored. Our main outcomes are the impacts of PTSSs on (1) alcohol use and (2) tobacco and nicotine use and their relation to COVID-19-related stressors (worries, exposure, lockdown, and infection, either of self or relatives). Results: Of the 503 reports identified, 44 were assessed for eligibility, and 16 were included in our review, encompassing 34,408 participants. The populations explored were the general population, healthcare workers, war veterans, patients with substance use disorders, and other vulnerable populations. Most studies were online surveys (14) with cross-sectional designs (11). Every study explored alcohol use, while only two assessed tobacco use. In most populations explored, a high level of PTSSs was associated with alcohol use increase. COVID-19-related stress was frequently correlated with either high PTSSs or alcohol use. In healthcare workers, PTSSs and alcohol use were not associated, while COVID-19 worries were related to both PTSSs and alcohol use. Discussion: 1. PTSSs and increased alcohol use are frequently associated, while COVID-19 worries might trigger both conditions and worsen their association. Alcohol use increase may represent either an inadequate way of coping with PTSSs or a vulnerability amid the COVID-19 pandemic, leading to PTSSs. As most studies were cross-sectional online surveys, longitudinal prospective studies are needed to ascertain the direction of the associations between these conditions. These studies need to be sufficiently powered and control for potential bias and confounders. 2. Our review highlighted that research about PTSSs and tobacco or nicotine use is scarce.
Investigating the Relationship between Parental Education, Asthma and Rhinitis in Children Using Path Analysis
Authors: Rocco Ilaria , Cilluffo Giovanna , Ferrante Giuliana , Cibella Fabio , Marcon Alessandro , Marchetti Pierpaolo , Ricci Paolo , Minicuci Nadia , La Grutta Stefania , Corso Barbara
Published: November 2022

Parental socioeconomic position (SEP) is a known determinant of a child’s health. We aimed to investigate whether a low parental education, as proxy of SEP, has a direct effect on physician-diagnosed asthma, current asthma and current allergic rhinitis in children, or whether associations are mediated by exposure to other personal or environmental risk factors. This study was a secondary data analysis of two cross-sectional studies conducted in Italy in 2006. Data from 2687 adolescents (10–14 years) were analyzed by a path analysis model using generalized structural equation modelling. Significant direct effects were found between parental education and family characteristics (number of children (coefficient = 0.6229, p < 0.001) and crowding index (1.1263, p < 0.001)) as well as with exposure to passive smoke: during pregnancy (maternal: 0.4697, p < 0.001; paternal: 0.4854, p < 0.001), during the first two years of children’s life (0.5897, p < 0.001) and currently (0.6998, p < 0.001). An indirect effect of parental education was found on physician-diagnosed asthma in children mediated by maternal smoking during pregnancy (0.2350, p < 0.05) and on current allergic rhinitis mediated by early environmental tobacco smoke (0.2002; p < 0.05). These results suggest the importance of promotion of ad-hoc health policies for promoting smoking cessation, especially during pregnancy.
Bias of Attentional Oscillations in Individuals with Subthreshold Depression: Evidence from a Pre-Cueing Facial Expression Judgment Task
Authors: Wu Wenfeng , Huang Xiaojiaqi , Qi Xin , Lu Yongbiao
Published: November 2022

Background: Study results regarding attentional bias in depressed individuals are inconsistent. Recent studies have found that attention is a discrete process, alternating between periods of either enhanced or diminished attention sensitivity. Whether a visual target can be detected depends on when it occurs relative to these oscillation rhythms. We infer that the inconsistency of attentional bias may be related to the abnormality of attentional oscillations in depressed individuals. Methods: A pre-cueing attentional task was used. We set 48 levels of stimulus onset asynchrony (SOA) between cues and targets and measured the response time (RT) of participants, as well as their EEG signals. Results: The RTs showed patterns of behavioral oscillations. Repeated-measure ANOVA indicated that subthreshold depressed participants had significantly higher RTs for negative expressions than for neutral but significantly lower RTs for positive than for neutral. The frequency analysis indicated that the RT oscillational frequency of subthreshold depressed participants to negative/positive expressions was different from that to neutral. The EEG time–frequency analysis showed that when faced with negative expressions, the intensity of the neural alpha oscillatory power of subthreshold depressed participants was significantly lower than that of normal controls. When faced with positive expressions, the intensity of neural alpha oscillatory power was significantly higher than that of normal controls. Conclusion: Compared to normal persons, subthreshold depressed individuals may have biases in both the amplitude and frequency of attentional oscillations. These attentional biases correspond to the intensity of their neural alpha wave rhythms.
Variation in Road Dust Heavy Metal Concentration, Pollution, and Health Risk with Distance from the Factories in a City–Industry Integration Area, China
Authors: Chen Yinan , Hu Zhiqiang , Bai He , Shen Wei
Published: November 2022

Road dust samples around three typical factories, F1, F2, and F3, in the National Zhengzhou Economic and Technology Development Zone (ZETZ), China, were collected to study the variation in heavy metal concentration (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn), pollution, and health risk with distance from the factories. The results indicated that the concentrations of all the elements near F1 were higher than near both F2 and F3. Apart from Co, Mn, and Cu in some dust samples, all the element concentrations were higher than the corresponding background values (BCs), to varying degrees. The spatial distributions of the heavy metals surrounding the factories followed the normal distribution. The peak values of element concentrations occurred at 300~400 m away from the factories, except for Hg, which continued increasing more than 500 m away from the factories. The fluctuation curves of the pollution load index value calculated according to the BCs for F1, F2, and F3 all had two peaks, a “small peak” and a “large peak”, appearing at about 30 m and 300 m, respectively. For the hazard index and the total carcinogenic risk, the peak values all appeared at 400 m, with the curves following the normal distribution. Exposure to road dust containing non-carcinogenic and carcinogenic elements around F1 was greater than around F2 or F3. In conclusion, our results provide a reference for pursuing effective prevention of dust heavy metal pollution around modern manufacturing factories.
Shift Work and Early Arterial Stiffness: A Systematic Review
Authors: Gusmão Waléria D. P. , Pureza Isabele R. O. M. , Moreno Claudia R. C.
Published: November 2022

Shift work is a way of organizing rotating schedules throughout the day. This can include 1–3 shifts for the same person on a rotational basis with other workers. Schedules that include night work have been associated with cardiovascular risk, mainly due to circadian misalignment. This systematic review sought to determine whether shift work is a risk factor for increased arterial stiffness. A systematic review of different databases was performed, using the following keywords: work shift, night work, arteriosclerosis, vascular stiffness, arterial stiffness, pulse wave velocity, and their Medical Subject Headings. We selected and analyzed 11 articles regarding pulse wave velocity as an indicator of arterial stiffness. Two studies identified higher levels of arterial stiffness in shift workers compared to day workers, while two studies found the opposite. In addition, four studies found no differences in arterial stiffness between shifts, two studies associated shorter sleep duration with arterial stiffness, and one study observed that physical activity could prevent adverse cardiovascular outcomes in shift workers. The findings are heterogeneous and preclude any robust conclusions. However, the present review points to the need for further studies to investigate arterial stiffness in shift workers, with greater control for confounding factors and longitudinal design.
Combined Effects of CO2 Adsorption-Induced Swelling and Dehydration-Induced Shrinkage on Caprock Sealing Efficiency
Authors: Shang Xiaoji , Wang Jianguo , Wang Huimin , Wang Xiaolin
Published: November 2022

Carbon dioxide (CO2) may infiltrate into the caprock and displace brine water in the caprock layer. This causes two effects: one is the caprock swelling induced by the CO2 adsorption and the other is the caprock dehydration and shrinkage due to CO2–brine water two-phase flow. The competition of these two effects challenges the caprock sealing efficiency. To study the evolution mechanism of the caprock properties, a numerical model is first proposed to investigate the combined effects of CO2 adsorption-induced expansion and dehydration-induced shrinkage on the caprock sealing efficiency. In this model, the caprock matrix is fully saturated by brine water in its initial state and the fracture network has only a brine water–CO2 two-phase flow. With the diffusion of CO2 from the fractures into the caprock matrix, the CO2 sorption and matrix dehydration can alter the permeability of the caprock and affect the entry capillary pressure. Second, this numerical model is validated with a breakthrough test. The effects of the two-phase flow on the water saturation, CO2 adsorption on the swelling strain, and dehydration on the shrinkage strain are studied, respectively. Third, the permeability evolution mechanism in the CO2–brine water mixed zone is investigated. The effect of dehydration on the penetration depth is also analyzed. It is found that both the shale matrix dehydration and CO2 sorption-induced swelling can significantly alter the sealing efficiency of the fractured caprock.
Capacity of Autonomous Sensory Meridian Response on the Reduction of Mental Stress
Authors: Inagaki Keiichiro , Ohta Yoshiyuki
Published: November 2022

In a social environment, various types of stress can be overwhelming. Humans frequently encounter these stressful situations in social life. Stress is divided into physical stress and mental stress; the latter is induced by heavy mental workloads and has become a huge social problem, leading to mental disorders and possibly suicide in the worst scenario. Investigations into monitoring mental stress and reducing stressful conditions are, therefore, important for its prevention. In the present study, we focused on autonomous sensory meridian response (ASMR) sound, which is known to improve the human mental condition through its comforting and relaxing effects. We investigated the effect of ASMR on the mental workload induced by mental tasks by the evaluation of EEG activation patterns in normal subjects. Our results showed a significant decrease in alpha-band activity and a significant increase in gamma (high beta)-band activity under the induction of mental workload by mental tasks compared to the resting condition. When applying ASMR sound, alpha- and gamma-band activity under the induction of mental workload by mental tasks was restored to the level of the resting condition. In conclusion, these results indicate that ASMR sound reduces the mental stress induced by mental workload.
Defining the Primary Work Stress Factors of Chinese Coal Miners—A Mixed-Methods Study
Authors: Di Hongxi , Ali Shujahat , Lu Yiming
Published: November 2022

Background: Studies have indicated that coal miners in China have higher levels of perceived job stress. However, few studies have investigated the work stress structure of coal miners. Objective: Our study focused on the work stress of coal miners in China, with a primary aim to determine the work stress structure of coal miners in China using a mixed-methods approach. Methods: Semi-structured interviews were performed with thirty-three people (team leaders and frontline coal miners) conducted with participants from various state-owned large- and medium-sized coal mines in China. Grounded theory was used to construct an initial model for the concept of coal miners’ work stress. Using the results of this initial survey and findings in the existing literature, we then constructed a preliminary questionnaire regarding coal miners’ work stress and administered the questionnaire to 900 coal miners in the Shaanxi, Henan, Inner Mongolia, and Gansu provinces. Results: The results show that the work stress structure for coal miners differs from that for other occupational types in China, due to differences in the Chinese culture and foreign cultural influences. We revised our questionnaire based on these considerations and administered a new survey to the frontline production workers in coal mines. The preliminary questionnaires were revised and analyzed through exploratory and confirmatory factor analysis, resulting in a final formal model for work stress, which was supported by content and structural validity. Conclusion: In this research, we used the framework of grounded theory to conduct an empirical analysis of the structure model of coal miners’ work stress. The findings support that the primary work stress factors of Chinese coal miners included the stress of the work environment, job responsibility, interpersonal relationships, career development, the family environment, and organizational systems. Coal enterprises should therefore always take these factors into consideration when developing and implementing safety management policies aimed at to improve the occupational health status of coal miners.
Rubber Antioxidants and Their Transformation Products: Environmental Occurrence and Potential Impact
Authors: Xu Jing , Hao Yanfen , Yang Zhiruo , Li Wenjuan , Xie Wenjing , Huang Yani , Wang Deliang , He Yuqing , Liang Yong , Matsiko Julius , Wang Pu
Published: November 2022

Antioxidants are prevalently used during rubber production to improve rubber performance, delay aging, and extend service life. However, recent studies have revealed that their transformation products (TPs) could adversely affect environmental organisms and even lead to environmental events, which led to great public concern about environmental occurrence and potential impacts of rubber antioxidants and their TPs. In this review, we first summarize the category and application of rubber antioxidants in the world, and then demonstrate the formation mechanism of their TPs in the environment, emphasizing their influence on the ozone oxidative degradation. The potential toxic effects of antioxidants and their TPs are further reviewed to improve understanding of their biological health impact and environmental risks. Finally, the environmental occurrences of antioxidants and their TPs are summarized and their environmental impacts are demonstrated based on the recent studies. Due to the currently limited understanding on the toxic and biological effects of these compounds, further studies are required in order to better assess various TPs of these antioxidants and their environmental impact. To our knowledge, this is the first review on antioxidants and their TPs in the environment, which may elevate the environmental risk awareness of rubber products and their TPs in the near future.
Loneliness and Social Support among the Middle-Aged and Elderly People with Visual Impairment
Authors: Chu Hui-Ying , Chan Hui-Shan
Published: November 2022

Loneliness is associated with depression, sleep disturbance, and an increased risk of cardiovascular disease, and it is a global public health problem. Since physical and mental health have a great impact on loneliness, middle-aged and elderly people who are blind or visually impaired may be more affected by loneliness. Previous research has confirmed that effective social support can enhance physical and mental health and alleviate the negative effects of life stress. Therefore, in this study, we applied a cross-sectional design where data were collected using questionnaires completed in person, by phone, or online for a total of 456 middle-aged and elderly people with visual impairment. We found that the enrolled participants who were unemployed, lacked a stable source of income, lived alone, or were unable to move independently were prone to experiencing high levels of loneliness and low social support, which highlights the necessity of interventions such as counseling to alleviate the sense of loneliness in such groups. During the COVID-19 pandemic, social support measures to reduce the sense of loneliness should be highly encouraged to ensure that middle-aged and elderly people with visual impairment can continue to live independently, and social support seems to be an important factor.
Health Care Use and Barriers to Care for Chronic Inflammatory Diseases (CID) among First and Second Generation South Asian Immigrant Children and Parents in Ontario Canada
Authors: Rishworth Andrea , Cao Tiffany , Niraula Ashika , Wilson Kathi
Published: November 2022

Although immigrants are disproportionately impacted by growing chronic inflammatory disease (CIDs) rates, yet suffer barriers to access health care, little attention has been given to their primary healthcare or specialist healthcare access as it relates to complex, chronic diseases in Canada, a country with universal health care. This study aims to investigate CID health care use and barriers to care among first- and second-generation immigrant South Asian children and parents in the Greater Toronto Area, Ontario. Drawing on analysis of 24 in depth interviews with children and parents (14 children, 10 parents), the results reveal that although CIDs disproportionately affects South Asian immigrants, they encounter health system, geographic, interpersonal, and knowledge barriers to access requisite care. These barriers exist despite participants having a GP, and are compounded further by limited familial systems, culturally insensitive care, and structural inequities that in some instances make parents choose between health access or other basic needs. Although all participants recognized the importance of specialized care, only 11 participants regularly accessed specialized care, creating new schisms in CID management. The findings suggest that a multisectoral approach that address individual and structural level socio-structural drivers of health inequities are needed to create more equitable healthcare access.
Access and Use of Health Services by People with Diabetes from the Item Response Theory
Authors: Siqueira Isabela Silva Levindo de , Guimarães Rafael Alves , Pagotto Valéria , Rosso Claci Fátima Weirich , Batista Sandro Rogério Rodrigues , Barbosa Maria Alves
Published: November 2022

The objective of this study was to analyze the indicators of access and use of health services in people with diabetes mellitus. This study used data from the National Health Survey, conducted in Brazil in 2013. The National Health Survey was carried out with adults aged 18 years or older residing in permanent private households in Brazil. Indicators from 492 individuals with self-reported diabetes mellitus living in the Central–West region of the country were analyzed. Item response theory was used to estimate the score for access to and use of health services. Multiple linear regression was used to analyze factors associated with scores of access and use of health services by people with diabetes mellitus. The mean score of access estimated by the item response theory and use estimated was 51.4, with the lowest score of zero (lowest access and use) and the highest 100 (highest access and use). Among the indicators analyzed, 74.6% reported having received medical care in the last 12 months and 46.4% reported that the last visit occurred in primary care. Only 18.9% had their feet examined and 29.3% underwent eye examinations. Individuals of mixed-race/skin color and those residing outside capital and metropolitan regions had lower access and use scores when compared to white individuals and residents of state capitals, respectively. The study shows several gaps in the indicators of access and use of health services by people with diabetes. People of mixed race/skin color and residents outside the capitals and metropolitan regions had lower scores for access and use, suggesting the need to increase health care in these groups.
Phase Angle as a Predictor for Physical Function in Institutionalized Independent Older Adults
Authors: Morais Ana , Ferreira Soraia , Martins Alexandre Duarte , Tomas-Carus Pablo , Marmeleira José , Parraca Jose A.
Published: November 2022

The aim of this study was to investigate the relationship between phase angle (PhA) and physical function in institutionalized, independent older adults. Physical function was evaluated using the Senior Fitness Test Battery. PhA was measured by electrical bioimpedance at 50 khz, and body composition parameters were also registered. Results showed that PhA significantly correlated with all physical fitness tests, except for arm curls. Regarding the results of the multivariate analysis, three models were created: Model 1, formed by a dependent variable “PhA” and two predictor variables “8 ft up-and-go” and “6 min walk”; Model 2, formed by a dependent variable “PhA” and three predictor variables “8 ft up-and-go”, “6 min walk” and “30-s chair stand”; and Model 3, formed by a dependent variable “PhA” and four predictor variables “8 ft up-and-go”, “6 min walk”, “30-s chair stand” and “arm curl”. Results showed that predictor variables had a significant influence on the PhA for all three models (Model 1: p = 0.001, 12.5%; Model 2: p = 0.002, 12.9%; and Model 3: p = 0.005, 13.1%). For women, Model 1 showed a significant influence of predictor variables on the PhA (p = 0.030, 9.3%). The results for men in Models 1, 2 and 3 showed significant influences on the PhA (p = 0.002, 31.2%; p = 0.006, 31.6%; and p = 0.016, 31.6%; respectively). This study confirmed previous studies regarding to the relationship between PhA and physical function. It also indicates that PhA could be an excellent predictor of physical function.
Exposure to Misinformation, Risk Perception, and Confidence towards the Government as Factors Influencing Negative Attitudes towards COVID-19 Vaccination in Malaysia
Authors: Mohamad Emma , Tham Jen Sern , Mohd Ajis Siti Zaiton , Hamzah Mohammad Rezal , Ayub Suffian Hadi , Tri Sakti Andi Muhammad , Azlan Arina Anis
Published: November 2022

Introduction: This study explored exposure to misinformation, COVID-19 risk perception, and confidence towards the government as predictors of negative attitudes toward the COVID-19 vaccine. Methods: A cross-sectional survey was carried out from 30 June to 30 August 2021 involving 775 respondents. The survey instrument for the questionnaire was an adaptation from various different studies consisting of five main variables: (1) misinformation about vaccination; (2) risk perception toward COVID-19; (3) attitudes toward the vaccination programme; (4) intention to get vaccinated; and (5) public confidence in the government in executing the vaccination programme. Results: The results of this study indicate that higher exposure to misinformation led to higher levels of negative attitudes toward the COVID-19 vaccine. When the perceived risk of COVID-19 infection was high, mistrust of vaccine benefits was low but there were also higher worries about the future effects of the vaccine. Confidence in the government was associated with lower negative attitudes toward the COVID-19 vaccine. Conclusion: The results of this study may help develop an understanding of negative attitudes toward vaccinations in Malaysia and its contributing factors.
Comparison of Root Ecological Stoichiometry between Non-Growing Season and Growing Season of Grassland on the Chang Tang Plateau
Authors: Ma Xingxing , Yan Yan , Hong Jiangtao , Wang Xiaodan
Published: November 2022

Root C: N: P stoichiometry affect the geochemical cycles of ecosystems, while a few studies were conducted on it and its relationship with soil nutrients, especially in the non-growing season. In this study, we investigated the root C:N:P stoichiometry of alpine steppe(AS), alpine meadow steppe(AMS), and alpine meadow(AM) in April (non-growing season) and August(growing season) in 2013. The results showed that: (1) There were no differences in root C, N, P, C: N, C:P, and N:P with a depth of AS in April. However, root C and C: N increased with depth, while N and N:P decreased with a depth of AS in August. In both months, the variation of root C, N, P, C: N with depth in AM was consistent with that of AS in August, and root C at deep layer decreased in August, which indicated roots of AM began to grow in April No significant difference of root C, N, C: N and N:P with depth was found, while P and C:P varied between the two months of AMS. Root P content at 20–30 cm was higher than that of other soil layers in April, which was significantly higher than that of AS, while no significant difference was found in August. (2) Grassland types had significant effects on soil nutrients (except TP) at 0–10 cm and 20–30 cm soil layers. (3) No significant correlation between soil nutrients and root C, N, P, C: N, C: P, and N: P was found in April. Soil TN and AN content had a significant positive correlation with root N: P, indicating that soil nitrogen was the primary N source of the root. Soil TP and AP were significantly negatively correlated with root C and C: N in August. This study can provide basic data and provide theoretical support for further understanding the role of grassland roots in nutrient cycling.
Effect of Hand Hygiene Intervention in Community Kindergartens: A Quasi-Experimental Study
Authors: Wu Shiyang , Wang Richard Szewei , Huang Yu-Ni , Wan Thomas T. H. , Tung Tao-Hsin , Wang Bing-Long
Published: November 2022

This study aimed to evaluate the effect of hand hygiene interventions on the overall hand hygiene (HH) status of teaching instruction of hand hygiene in kindergartens, given the vulnerability of kindergarten children and their high risk due to infectious diseases and the current COVID-19 epidemic. We investigated the HH status of teachers from two kindergartens in the same community. The participants were recruited from 28 classes in both kindergartens. After completing the baseline survey, the intervention program consisted of three components: lectures on infectious diseases, lectures on HH, and seven-step hand washing techniques conducted in two kindergartens. The intervention program effectively increased teachers’ perceived disease susceptibility (p < 0.05), reduced the total bacterial colonization of children’s hands (p < 0.001), and improved the HH environment (p < 0.01). We recommend that health authorities or kindergartens adopt this HH intervention program to effectively improve the HH status in kindergartens and allow for preventive responses to the COVID-19 epidemic or other emerging infectious diseases.
Effects of Fatigue Induced by Repeated Sprints on Sprint Biomechanics in Football Players: Should We Look at the Group or the Individual?
Authors: Romero Valentin , Lahti Johan , Castaño Zambudio Adrián , Mendiguchia Jurdan , Jiménez Reyes Pedro , Morin Jean-Benoît
Published: November 2022

The aim of this study was to analyse the influence of fatigue on sprint biomechanics. Fifty-one football players performed twelve maximal 30 m sprints with 20 s recovery between each sprint. Sprint kinetics were computed from running speed data and a high-frequency camera (240 Hz) was used to study kinematic data. A cluster analysis (K-mean clustering) was conducted to classify individual kinematic adaptations. A large decrease in maximal power output and less efficiency in horizontally orienting the ground reaction force were observed in fatigued participants. In addition, individual changes in kinematic components were observed, and, according to the cluster analysis, five clusters were identified. Changes in trunk, knee, and hip angles led to an overall theoretical increase in hamstring strain for some players (Cluster 5, 20/51) but to an overall decrease for some others (Cluster 1, 11/51). This study showed that the repeated sprint ability (RSA) protocol had an impact on both kinetics and kinematics. Moreover, fatigue affected the kinematics in a different way for each player, and these individual changes were associated with either higher or lower hamstring length and thus strain.
Considerations for Evaluating the Introduction of New Cancer Screening Technology: Use of Interval Cancers to Assess Potential Benefits and Harms
Authors: Farber Rachel , Houssami Nehmat , Barnes Isabelle , McGeechan Kevin , Barratt Alexandra , Bell Katy J. L.
Published: November 2022

This framework focuses on the importance of the consideration of the downstream intermediate and long-term health outcomes when a change to a screening program is introduced. The authors present a methodology for utilising the relationship between screen-detected and interval cancer rates to infer the benefits and harms associated with a change to the program. A review of the previous use of these measures in the literature is presented. The framework presents other aspects to consider when utilizing this methodology, and builds upon an existing framework that helps researchers, clinicians, and policy makers to consider the impacts of changes to screening programs on health outcomes. It is hoped that this research will inform future evaluative studies to assess the benefits and harms of changes to screening programs.
Physical Activity and Physical Fitness in Adolescents after the COVID-19 Lockdown and One Year Afterward
Authors: Carriedo Alejandro , Cecchini Jose Antonio , Fernández-Álvarez Luis Enrique , González Carmen
Published: November 2022

The purpose of this study was to analyze the changes in physical activity and physical fitness between the beginning of the first academic year after a confinement (November 2020) and the beginning of the second academic year after a confinement (“new normality”: November 2021) in a cohort of adolescents. Moreover, the evolution of physical fitness after controlling for physical activity was examined. A total of 687 students (M = 15.35, SD = 1.677) from a high school located in a rural town in northern Spain gave information on their physical activity (PA) levels in two different periods. Linear mixed models were used to examine these changes. The results indicated that vigorous physical activity (VPA) and the metabolic equivalent of task (MET) significantly increased between the two periods. A growth tendency of several components of fitness (upper body power, strength endurance, cardiovascular fitness, flexibility, and eye–hand coordination) was also observed. Finally, the results indicated that belonging to a sports club and getting involved in more VPA better explained the development in cardiovascular and muscle fitness between the two time points. Thus, the results of this study highlighted the relevance of membership in a sports club and vigorous PA in order to mitigate the potential negative effect of social distancing measures on physical fitness.
Panic Detection Using Machine Learning and Real-Time Biometric and Spatiotemporal Data
Authors: Lazarou Ilias , Kesidis Anastasios L. , Hloupis George , Tsatsaris Andreas
Published: November 2022

It is common sense that immediate response and action are among the most important terms when it comes to public safety, and emergency response systems (ERS) are technology components strictly tied to this purpose. While the use of ERSs is increasingly adopted across many aspects of everyday life, the combination of them with real-time biometric and location data appears to provide a different perspective. Panic is one of the most important emergency indicators. Until now, panic events of any cause tend to be treated in a local manner. Various attempts to detect such events have been proposed based on traditional methods such as visual surveillance technologies and community engagement systems. The aim of this paper is twofold. First, it presents an innovative multimodal dataset containing biometric and spatiotemporal data associated with the detection of panic state in subjects that perform various activities during a certain period. For this purpose, time-enabled location data are combined with biometrics coming from wearables and smartphones that are analyzed in real-time and produce data indicating possible panic events that are geospatially described. Second, the proposed dataset is used to train various machine learning models, and their applicability to correctly distinguish panic states from normal behavior is thoroughly examined. As a result, the Gaussian SVM classifier ranked first among seven classifiers, achieving an accuracy score of 94.5%. The dataset was also tested in a deep learning framework, achieving an accuracy level of 93.4%. A long short-term memory approach was also used, which reached a top accuracy of 94%. Moreover, the contribution of the various biometric and geospatial features is analyzed in-depth to determine their partial importance in the overall panic detection process. This is moving towards the creation of a smart geo-referenced ERS that could be used to inform the authorities regarding a potentially unpleasant event by detecting possible crowd panic patterns and helping to act accordingly, getting the information right from the source of the event, the human body. The proposed dataset is freely distributed to the scientific community under the third version of GNU General Public License (GPL v3) through the GitHub platform.
A Spark-Based Artificial Bee Colony Algorithm for Unbalanced Large Data Classification
Authors: Al-Sawwa Jamil , Almseidin Mohammad
Published: November 2022

With the rapid development of internet technology, the amount of collected or generated data has increased exponentially. The sheer volume, complexity, and unbalanced nature of this data pose a challenge to the scientific community to extract meaningful information from this data within a reasonable time. In this paper, we implemented a scalable design of an artificial bee colony for big data classification using Apache Spark. In addition, a new fitness function is proposed to handle unbalanced data. Two experiments were performed using the real unbalanced datasets to assess the performance and scalability of our proposed algorithm. The performance results reveal that our proposed fitness function can efficiently deal with unbalanced datasets and statistically outperforms the existing fitness function in terms of G-mean and F1-Score. In additon, the scalability results demonstrate that our proposed Spark-based design obtained outstanding speedup and scaleup results that are very close to optimal. In addition, our Spark-based design scales efficiently with increasing data size.
Research on Data Transaction Security Based on Blockchain
Authors: Jiang Yongbo , Sun Gongxue , Feng Tao
Published: November 2022

With the increasing value of various kinds of data in the era of big data, the demand of different subjects for data transactions has become more and more urgent. In this paper, a blockchain-based data transaction protection scheme is proposed to realize the secure transaction sharing among data. This paper carries out the following work: by analyzing the existing data transaction models, we find the data security and transaction protection problems, establish a third-party-free data transaction platform using blockchain, protect users’ data security by combining AES and improved homomorphic encryption technology, and upload the encrypted data to the Interplanetary File System (IPFS) for distributed storage. Finally, we use the powerful functions of the IPFS, combined with inadvertent transmission protocol, two-way authentication, zero-knowledge proof, and other security verification for data transactions. The security analysis proves that this scheme has higher security despite the time overhead, and we will continue to optimize the scheme to improve efficiency in the future.
Cold Sintering Process of Zinc Oxide Ceramics: Powder Preparation and Sintering Conditions Effects on Final Microstructure
Authors: Smirnov Andrey V. , Kornyushin Maxim V. , Kholodkova Anastasia A. , Melnikov Sergey A. , Stepanov Artem D. , Fesik Elena V. , Ivakin Yurii D.
Published: November 2022

Although the activating effect of an acetate medium in the cold sintering process of zinc oxide ceramics is well known, some problems need to be solved on the effect of process conditions and the initial powder’s preparation methods on the ceramic’s density and microstructure. This article describes an effect of the zinc acetate introduction method, its concentration in zinc oxide powder as well as that of the die sealing configuration on the density and microstructure of zinc oxide ceramics obtained by the cold sintering process at 244 °C. The activating additive of zinc acetate was applied in two ways: (1) impregnation in aqueous solution and (2) impregnation with subsequent treatment in water vapor. Zinc oxide powders and ceramics were analyzed using SEM, TGA/DSC/MS and XRD to reveal the effect of powder pre-treatment and sintering conditions on the material microstructure. Cold sintered ZnO ceramics samples with a relative density up to 0.99 and with average grain sizes from 0.28 to 1.71 μm were obtained. The die sealing by two Teflon sealing rings appeared to be the most effective.
New Ferrocene-Based Metalloligand with Two Triazole Carboxamide Pendant Arms and Its Iron(II) Complex: Synthesis, Crystal Structure, 57Fe Mössbauer Spectroscopy, Magnetic Properties and Theoretical Calculations
Authors: Antal Peter , Nemec Ivan , Pechoušek Jiří , Herchel Radovan
Published: November 2022

The new ferrocene-based metalloligand bis (N-4-[3,5-di-(2-pyridyl)-1,2,4-triazoyl])ferrocene carboxamide (L) was prepared through derivatization of 1,1′-ferrocenedicarboxylic acid with 4-amino-3,5-di(pyridyl)-4H-1,2,4-triazole. The composition and purity of L in the solid state was determined with elemental analysis, FT-IR spectroscopy, and its crystal structure with single-crystal X-ray analysis, which revealed that the substituted cyclopentadienyl rings adopt the antiperiplanar conformation and the crystal structure of L is stabilized by O–H···N and N–H···O hydrogen bonds. The molecular properties of L in solution were investigated with NMR and UV-VIS spectroscopies, and cyclic voltammetry disclosed irreversible redox behavior providing one oxidation peak at E1/2 = 1.133 V vs. SHE. Furthermore, the polymeric FeII complex {Fe(L)(C(CN)3)2}n (1) was prepared and characterized with elemental analysis, FT-IR spectroscopy, 57Fe Mössbauer spectroscopy, and magnetic measurements. The last two methods confirmed that a mixture of low- and high-spin species is present in 1; however, the spin crossover properties were absent. The presented study was also supported by theoretical calculations at the DFT/TD-DFT level of theory using TPSS and TPSSh functionals.
Flubendiamide Resistance and Its Mode of Inheritance in Tomato Pinworm Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)
Authors: Zang Lian-Sheng , Akhtar Zunnu Raen , Ali Asad , Tariq Kaleem , Campos Mateus R.
Published: November 2022

Tomato pinworm, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is the major pest of tomato crops in Pakistan. Insecticides are commonly used for the management of this insect-pest. To develop a better insecticide resistance management strategy and evaluate the risk of resistance evolution, a field collected population of the tomato pinworm was selected with flubendiamide in the laboratory. We investigated the genetics of flubendiamide resistance and concentration-mortality response to other insecticides by selecting a field strain of tomato pinworm with commercial flubendiamide formulation. Tuta absoluta was reciprocally crossed with resistant strain (Fluben-R) and was selected up to 13 generations, while F1 progeny was back-crossed with resistant parent (Fluben-R). The results of LC50 and Resistance Ratio (RR) demonstrated a higher resistance developed in field and laboratory-selected strains (G2 and G13, respectively). Field-collected and laboratory-selected (Fluben-R) strains demonstrated higher intensity of concentration-mortality response against chlorantraniliprole, thiamethoxam, permethrin, abamectin and tebufenozide compared to susceptible ones. Based on the overlapping of 95% FL, it demonstrated significant differences, revealing that it was not sex linked (autosomal) with no maternal effects. The backcross analysis of the F1× resistant parent resulting in significant differences at all concentrations suggests that resistance is controlled by more than one factor; the null hypothesis was rejected and inheritance was under polygenic control. Resistance progression from 38 to 550 folds demonstrated that T. absoluta can develop a higher level of resistance to flubendiamide. Concentration-mortality response experiments demonstrated that the LC50 of some tested insecticides was higher for field-collected and laboratory-selected strains, suggesting that resistance mechanisms should be studied at a molecular level for better understanding. These results could be helpful to design resistance management strategies against the tomato pinworm.
Identification and Expression Analysis of Odorant-Binding and Chemosensory Protein Genes in Virus Vector Nephotettix cincticeps
Authors: Chang Xuefei , Bi Yaluan , Chi Haipeng , Fang Qi , Lu Zhaozhi , Wang Fang , Ye Gongyin
Published: November 2022

The insect odorant binding proteins (OBPs) and chemosensory proteins (CSPs) are involved in the perception and discrimination of insects to host odor cues. Nephotettix cincticeps, one of the destructive pests of rice plants, not only directly damages hosts by sucking, but also indirectly transmits plant viruses in the field. Previous study found that two rice volatiles ((E)-β-caryophyllene and 2-heptanol) induced by rice dwarf virus (RDV) mediated the olfactory behavior of N. cincticeps, which may promote virus dispersal. However, the OBPs and CSPs in N. cincticeps are still unknown. In this study, to identify the OBP and CSP genes in N. cincticeps, transcriptomic analyses were performed. In total, 46,623 unigenes were obtained. Twenty putative OBP and 13 CSP genes were discovered and identified. Phylogenetic analyses revealed that five putative OBPs belonged to the plus-C OBP family, and the other classic OBPs and CSPs were distributed among other orthologous groups. A total of 12 OBP and 10 CSP genes were detected, and nine OBP and three CSP genes were highly expressed in N. cincticeps antennae compared with other tissues. This study, for the first time, provides a valuable resource to well understand the molecular mechanism of N. cincticeps in the perception and discrimination of the two volatiles induced by RDV infection.
Collembola from Two Samplings in the MSS of the Sierra de Guadarrama National Park in Two Different Seasons, with Description of a New Species
Authors: Baquero Enrique , Jordana Rafael
Published: November 2022

An intensive sampling in a colluvial mesovoid shallow substratum (MSS) of the Sierra de Guadarrama National Park, using 33 subterranean sampling devices (SSDs) is the origin of the Collembola studied in this paper. The data were obtained from the second extraction of the traps, in operation between October of 2015 and May of 2016. This paper presents the faunistic and diversity data along with the entire park (mostly at sampling points above 200 m a.s.l.) for this period, compares the data between the first extraction of the traps and the second one, and describes one species of the genus Pseudosinella that appears as new in the second campaign.
Differentiation of Developmental Pathways Results in Different Life-History Patterns between the High and Low Latitudinal Populations in the Asian Corn Borer
Authors: Fu Shu , Huang Lili , He Haimin , Tang Jianjun , Wu Shaohui , Xue Fangsen
Published: November 2022

Individual insects often exhibit two alternative pathways of non-diapausing and diapausing developments. Yet, most studies have focused on the latitudinal variation in life-history traits for non-diapausing individuals. No study has examined the differences in life history traits between non-diapausing and diapausing individuals along a latitudinal gradient. We used six different geographical populations of Ostrinia furnacalis to examine the latitudinal variation in life-history traits between non-diapausing and diapausing individuals in terms of their sex ratio, larval and pupal developmental times, pupal weight, growth rate, adult weight and weight loss, and sexual size dimorphism. The results showed that latitudinal variation in life-history traits for both non-diapausing and diapausing individuals exhibited a sawtooth pattern, but the life-history pattern of the two alternative developmental pathways was significantly different between the high and low latitudes. For the non-diapausing pathway, the high-latitudinal populations showed a significantly shorter larval developmental time, higher growth rate and greater body weight than the low-latitudinal populations, suggesting countergradient variation. Conversely, in the diapausing pathway, the high-latitudinal populations had longer larval developmental times, lower growth rates and relatively smaller body weights than the low-latitudinal populations, suggesting cogradient variation. We also found that in the high-latitudinal populations, larvae in the non-diapausing pathway had shorter developmental time and higher body weight, whereas larval developmental time of the low-latitudinal populations was longer and the body weight was smaller. The relationship between larval developmental time and pupal weight was also different between the two developmental pathways. These results provide new insights into the evolution of life-history traits in this moth.