bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Egg-cartons as simulated models for teaching tooth brushing to Preschool Children - A randomized control trial
Authors: Arora Ankita , Yen Hui Lee , Chew Sze Lee , Yee Sing Teoh , Kyaw Soe Htoo Htoo
Published: August 2022

Background: Oral Health Programme, Ministry of health, Malaysia highlights the need to enhance oral health promotion and prevention of oral disease for preschool children. Developing and exploring engaging methods of education that enable young children in dental hygiene practices is a way forward in oral health promotion. Objectives: To develop novel activity based tooth brushing teaching method for preschool children using egg cartons as simulated teeth models and evaluate effectiveness of the same Methods: Two methods of teaching tooth brushing technique to preschool children in the age 4 to 6 years were compared through a Randomized Control Trial.: (i) Conventional method (N=32): Instructions on study model (ii) Egg carton simulation method (N=34): Hands on activity on egg cartons as simulated models. Outcome assessed was plaque index (Silness and Loe, 1964) Results: Plaque scores compared using Dependent t-test shows significant improvement in both groups after the teaching sessions (P<.01 for both the methods). However, comparing both methods with each other by independent t-test shows an insignificant difference (P>.01). Conclusion: Egg carton simulation method is as good as the conventional approach as there is significant plaque score reduction in children after the teaching session.
FIELD STUDIES OF THE SECOND FLOOR OF THE FORMER GRAND HOTEL BUILDING, 5 F. SKORINA AVENUE, POLOTSK
Authors: SOLOVIOV A.
Published: August 2022

The article provides the results of a full-scale study of the second floor of the former Grand Hotel Building. The probing of the walls revealed a number of reconstructions of the building at different times and made it possible to clarify its original layout. The most extensive reconstructions of the building took place in 1874, 1912 and 1971, which led to the complete loss of all elements of its original interiors.

During the study of the masonry of the existing building, a fragment of the wall of an XVIIIth century building was found as part of the studied floor, about which there is no information. The outlines of the brick building in the western part of the object we are studying are known only from the plans of Polotsk at the end of the XVIIIth century, but its purpose and type of architecture are not indicated. During the work, a number of architectural elements of the eastern facade of this building were cleared – the remnants of windows and cornices. It was found that in the middle of the XIXth century during the construction process in the eastern part of the "Grand Hotel" at the level of the second floor, it was connected with the building of the XVIIIth century that we have identified. By that time, it had already been rebuilt through two arched openings. This indicated that both buildings had the same owner for some time, but soon they were divided and completely isolated from each other.

The buildings were connected again only after 1912 by arranging a new passage and using vaults on rails as ceilings for the entrance and toilets.
ASSESSMENT OF THE ACCURACY OF PHOTOPLAN
Authors: MIKHEEVA A. , YALTYKHOV V. , PARADNYA P.
Published: August 2022

When using analog aerial cameras, photomaps were assembled from transformed images. If the elevation of the points of the terrain made it possible to obtain acceptable distortions for the relief, then they were transformed into one zone. Otherwise, the transformation was performed by zones, allowing displacements in each zone of no more than 0.4 mm. In neighboring zones, the displacements at the zone boundary had opposite directions, and the discrepancy between the contours could reach 0.8 mm. Its average value was taken as the final position of the contour, which compensated for position errors in neighboring zones.

When creating digital photomaps and orthophotomaps, digital elevation models (DEM) are used to account for terrain distortions. Digital transform technology does not use transform zones and therefore will not compensate for errors as it would with zone transforms. The quality of the orthomosaic will depend on the accuracy of the DEM. A digital model of a relief or surface has a high density and makes it possible to take into account distortions for the relief much more accurately than when transforming by zones.

The paper analyzes the requirements of the current regulatory documents when creating digital photomaps and orthophotomaps, provides relevant conclusions and recommendations.
SPATIAL ORGANIZATION OF AN INDUSTRIAL ENTERPRIZE – THE HISTORY OF TYPE DEVELOPMENT
Authors: MOROZOVA Y.
Published: August 2022

In historical retrospect there is examined the spatial organization of an industrial enterprise as a typological unit in architecture. The techniques of the placement of buildings, structural-functional and compositional organization of the site, the time of their distribution, general approaches to the space formation are given.
Rezension von: Böhmer, Hans Jürgen, Beim nächsten Wald wird alles anders
Authors: Wolf Reinhard , Böhmer Hans Jürgen
Published: August 2022

Hans Jürgen Böhmer: Beim nächsten Wald wird alles anders – das Ökosystem verstehen Hirzel Verlag, Stuttgart 2022. 206 Seiten. Fester Einband 22 €. ISBN 978-3-7776-2922-3
Persepsi Orang Tua Dalam Pembelajaran Daring Di Dukuh Beji Selama Pandemi Covid-19
Authors: Arsena Alvian , Erik Aditia Ismaya  , Muhammad Noor Ahsin
Published: August 2022

Terjadinya pandemi virus Covid-19yang berdampak pada seluruh masyarakat salam satunya adalah pendidikan. karena situasi yang menghawatirkan pemerintah mengeluarkan kebijakan untuk belajar di rumah atau daring hal tersebut menimbulkan berbagai persepsi pada orang tua. Berdasarkan observasi yang di lakukan di dukuh Beji orang tua memilik kesulitan dalam mendampingi anak saat belajar daring dikarenakan kesibukan oarng tua dalm bekerja, kurang paham dengan cara kerja pembelajaran daring, dan permaslahan dengan jaringan yang susah.tujuan penenelian ini adalah untuk mengetahui persepsi orang tua pada pembelajaran daring, dampak apa saja yang di rasakan orang tua, dan upaya dallam mendampingi anak belajar daring.. Hasil dari penelitian tentang dilaksanakannya pembelajaran daring orang tua memiliki persepsi yang berbeda ada yang setuju dan tidak dengan adanya daring, setuju karena berkat adanya daring orang tua mersa lebih aman anaknya belajar di rumah, Anak masih bisa belajar walaupun tidak tatap muka langsung di sekolah dan daring membuat pembelajaran menjadi lebih cepat dan mudah. Dan yang membuat tidak sejutu Pertama orang tua kesulitan membagi waktunya antara pekerjaan dan mendampingi anak belajar, Anak kesusahan memahami materi tua kesusahan dalam mengikuti pembelajaran daring.

Kata Kunci: Persepsi orang tua; Pembelajaran Daring; COVID-19
Development Of Multimedia Ict-Based Online Learning (Cai, Cbi, Mobile Learning And E-Learning) In The Age Of Industrial Revolution 4.0 And Society 5.0
Authors: Anam Nurul
Published: August 2022

The purpose of this study is to describe the development of online learning based on Multimedia ICT in the Industrial Revolution Age 4.0 and Society 5.0. This research method uses a qualitative method with the type of library research. The results of the study indicate that as part of the effort to reform learning is to take advantage of ICT in learning activities. One of the ICT products that can be used in learning is a computer or laptop/netbook, an Android cellphone and the Internet. By applying ICT-based learning, students can learn "from" and "with" ICT products. Learning "from" ICT products is carried out using ICT-based learning such as from products in the form of CAI, CBI, Mobile Learning and E-Learning. Learning "with" technology is the use of technology as cognitive tools and the use of technology in a constructivist learning environment. Thus, the role of ICT-based multimedia in learning is becoming increasingly significant today, because these media are designed to complement each other so that the desired learning objectives will be achieved properly.
Studi Korelasi Antara Literasi Digital Dan Minat Belajar Siswa Pada Era Pandemi Covid-19
Authors: Melati Dita Puti , Abdul Rahman  , Nurhadi
Published: August 2022

Abstract :

Learning interest deserves attention by teachers, schools and societies. Digital literacy should be the solution. The pandemic Covid-19 has caused downgrading student learning interest. The research objective was to analyse the correlation between digital literacy and student learning interest. This research found that the more variety of digital literacy activities the higher students’ learning interest. Digital literacy platforms allow students to access and apply technology in obtaining, using, and sharing data dan information for learning. Quantitative data were collected from 298 students in Surakarta. Findings showed that rxy.678 meaning that the correlation between digital literacy(X) and learning interest(Y) is positively significant. Moreover we found that the rxy.632 for the classroom digital literacy (X1), rxy.609 for the school digital literacy (X2), and rxy.532 for social digital literacy (X3), all findings show positive contribution to learning interest. Thus, teachers, parents, and society can improve learning interest. We recommend that digital literacy should work in class, schools and community.

Keywords: Digital literacy, student learning interest, pandemic Covid-19.  

Abstrak :

Minat belajar patut mendapat perhatian guru, sekolah dan masyarakat. Literasi digital harus menjadi solusi. Pandemi Covid-19 menyebabkan menurunnya minat belajar siswa. Penelitian ini bertujuan untuk menganalisis hubungan literasi digital dengan minat belajar siswa. Penelitian ini menemukan bahwa semakin beragam kegiatan literasi digital semakin tinggi minat belajar siswa. Platform literasi digital memungkinkan siswa untuk mengakses dan menerapkan teknologi dalam memperoleh, menggunakan, dan berbagi data dan informasi untuk pembelajaran. Data kuantitatif dikumpulkan dari 298 siswa di Surakarta. Hasil penelitian menunjukkan bahwa rxy.678 yang berarti korelasi antara literasi digital (X) dan minat belajar (Y) signifikan secara positif. Selain itu kami menemukan bahwa rxy.632 untuk literasi digital kelas (X1), rxy.609 untuk literasi digital sekolah (X2), dan rxy.532 untuk literasi digital sosial (X3), semua temuan menunjukkan kontribusi positif terhadap minat belajar. Dengan demikian, guru, orang tua, dan masyarakat dapat meningkatkan minat belajar. Kami merekomendasikan bahwa literasi digital harus bekerja di kelas, sekolah dan masyarakat.

Kata Kunci:  Literasi digital, minat belajar, pandemic Covid-19
Downstream Effects of Industrial Effluents Discharge on Some Physicochemical Parameters and Water Quality Index of River Rido, Kaduna State, Nigeria
Authors: Butu Ali Williams , Emeribe Chukwudi Nnaemeka , Muoka Ijeoma Obianuju , Emeribe Oluchi Favour , Ogbomida Emmanuel Temiotan
Published: August 2022

The effects of industrial effluent discharge on the water quality of River Rido in Kaduna South, Kaduna State, were examined. These include the Northern Noodles discharge point, the Kaduna Refinery discharge point, and points downstream of the River Rido. An interval of 100m between sampling points was established to achieve an even representation of sampling points. The physico-chemical parameters investigated include pH, free dissolved carbon dioxide, alkalinity, hardness, sodium, electrical conductivity, Turbidity, total suspended solids, total phosphate, nitrate, sulfate, and dissolved oxygen. Mean levels of turbidity Total suspended solids and total phosphate at effluent discharge points, as well as in most areas downstream of the study area, were generally above permissible limits for drinking water. Statistical differences were observed in the concentration levels of investigated parameters between the control point and effluent discharge points, as well as between the control point and areas downstream of the study area. However, concentration levels were observed to be similar between discharge points and areas downstream of the study area, an indication of contamination downstream by effluent discharge upstream. Notwithstanding, the water quality index of physico-chemical parameters at both effluent discharge points and areas downstream of River Rido shows that the quality of the river ranged from good to excellent at effluent discharge points and areas downstream of River Rido, respectively. This might be attributed to the effect of dilution from rainfall. It is therefore recommended that wastewater effluent from the refinery and northern noodles be properly treated before discharged into the study area.
Short term outcome of Gustilo Anderson open type 3A mid shaft tibia fractures using intramedullary interlocking nail and external fixator
Authors: Ayoub Idrees , Malik Anzar Tariq , Singh Tejpal , Basit Abdul , Arfee Sakib
Published: August 2022

Aim: The purpose of the present study is to assess the outcome of treating Gustilo Anderson open Type 3A mid shaft tibia fracture with intramedullary interlocking nail as well as external fixator. Methodology: In this prospective cohort study, adult patients (≥18 years-old) with Gustilo 3A open tibia shaft fractures treated by either intramedullary nail or external fixation (EF) were involved. This study was directed for a period of twelve months from March 2021 to February 2022. After registration, patients were followed-up at 2, 6, 10, 14, and 18 weeks postoperatively. At these appointments, degree of callus formation at fracture site and surgical problems (e.g. infection, limb length discrepancy, malalignment) were assessed. Results: Out of 50 patients registered in the study, 26 were treated by IM nail and 24 by external fixation. Twenty-four patients (92.3%) in the IM nail group and 6 (25%) in the external fixation group had callus formation by the 10th week. The mean times to callus formation in the IM nail group and external fixation group were 8.2±2.6 weeks and 14.7±3.3 weeks, individually (p=0.000). Two (7.7%) patients in the IM nail group and 3 (12.5%) in the external fixation group developed infection (p=0.661).
Study of homocysteine and its correlation with biochemical parameters in patients with chronic renal failure
Authors: Shaker Riyam
Published: August 2022

Homocysteine is an amino acid produced when proteins are broken down. A high homocysteine level, also called hyperhomocysteinemia, can contribute to arterial damage and blood clots in your blood vessels. Hyperhomocysteinemia (Hhcy) occurs in chronic kidney disease (CKD) patients because of impaired renal metabolism and reduced renal excretion Chronic renal failure is a condition involving a decrease in the kidneys' ability to filter waste and fluid from the blood. It is chronic, meaning that the condition develops over a long period of time and is not reversible. The condition is also commonly known as chronic kidney disease (CKD). The aim of the study is to measure homocysteine levels for patients with chronic renal failure before dialysis and to find the relationship between homocysteine and biochemical parameters such as B12, folic acid, ferritin and albumin. Study Design: Blood samples were obtained from (130) men and women. It was divided into (68) hemodialysis patients, aged from (20-80) years and (62) control, aged from (20-80) years, and they were campared.
Niosomes: A promising nonionic surfactant vesicular system for enhancement of anticancer effect of phytochemicals
Authors: Jawale Jyoti K. , Kashikar Vushali S.
Published: August 2022

In recent years, infectious illness therapy and vaccination have experienced a dramatic transformation. With the progress of biotechnology, not only have a great number of disease-specific biologicals been generated, but there has also been an emphasis on delivering these biologicals efficiently. Niosomes are non-ionic surfactant-based vesicles that are biodegradable, largely non-toxic, more stable, and less costly than liposomes. Non-ionic surfactant-based vesicles, also known as niosomes, have garnered a great deal of interest in the pharmaceutical industry due to its ability to encapsulate both hydrophilic and hydrophobic substances. In recent years, it has been shown that these vesicles can enhance the bioavailability of medications and may serve as a novel technique for delivering a variety of therapeutic agents, including chemical pharmaceuticals, protein therapeutics, and gene materials, with minimal toxicity and the desired targeting effectiveness. This page also provides an overview of niosome preparation processes, niosome kinds, characterisation, and applications. Chemoprevention is the use of phytochemicals to prevent or reduce cancers. It has been shown that several compounds produced from plants possess anticancer properties.
Determination And Identification the Awareness of Primary Eye Care in Community
Authors: Jan Nawar , Anjum Misra , Ahmad Muhammad , Anwar Faridi Tallat , Iqbal Samia , Mujahid Muhammad , Hussain Abid
Published: August 2022

Vision is the essential part of our life. A good eye health is necessary to perform a lot of works such as cooking, sewing, studding, driving. it affects our social, economic life. Vision also affects the quality of life and a person’s physical and mental state. Objective: The study's main goal was to find out how much people in the community knew about primary eye care. Methods: A cross-sectional survey with questionnaires was done. The research site, target population, sample size (194 people), sampling method, research methodology, and work plan were all chosen. Results: The level of knowledge and awareness in the community was about average. Most people don't know much about primary eye care because there aren't many places to get information, and they can't access services. The study had 194 people sign up, of which 48.9% were men and 52.2% were women. 58.9% of the participants of study, were well aware and knew about basic eye care. Associated factors with awareness of Health care worker of community about Primary Eye Care showed significant association. Conclusion: Most people in the community know about primary eye care, and the results of this study seem to back up what they know. However, teaching people about primary eye care and eye care services is time. I would suggest through this study, to take extra measures to improve general awareness about eye care in community through social media and print media or papers so that people can avoid common eye diseases.
Analysis of Factors Affecting Community Participation Expectations on Sustainability Urban Farming in Jakarta City
Authors: Salim M. Noor , Wibowo Edi Wahyu , Susilastuti Darwati , Diana Tungga Buana
Published: August 2022

To meet the nutritional needs of the people of Jakarta, urban agriculture is one of the food supply solutions. This study analyzes community expectations for participation in sustainable urban agriculture in Jakarta. The latest developments of this study provide results on the impact of economic, health and environmental variables on people's expectations for the sustainability of urban agriculture in Jakarta. The novelty of this study is that it considers the theme of the study, namely the inhabitants of the city of Jakarta, engaged in urban agriculture, a total of 112 respondents. The results of this study indicate that economic, health and environmental variables, simultaneously or in part, positively influence the expectations of community involvement in the sustainability of urban agricultural activities in the city of Jakarta. Based on these findings, it can be said that the expectation of community engagement in sustainable urban agriculture in Jakarta translates into greater productivity, knowledge, skills, awareness and understanding of the existence of clear regulations. The corrected R-square value is 0.704 based on the results of the coefficients that determine the impact of economic, health and environmental factors on community participation expectations in the sustainability of urban agriculture in Jakarta. In other words, 70.4% of community participation expectations in urban agriculture depend on economic factors, while health and other environmental factors depend on other factors. Expectations for community involvement in sustainable urban agriculture are already high and Jakarta's food security can be ensured later.
Hubungan Pengetahuan Wanita Usia Subur terhadap Sikap Deteksi Dini Kanker Serviks di Kelurahan Margomulyo Kabupaten Ngawi
Authors: Salsabilla Afriza Alya , Daris Hamidatus , Kurniasih Erwin
Published: August 2022

Kanker serviks merupakan tumor ganas yang berkembang di dalam leher rahim atau serviks (bagian terendah dari rahim yang melekat pada puncak vagina). Tujuan dari penelitian ini untuk mengetahui hubungan pengetahuan wanita usia subur terhadap sikap deteksi dini kanker serviks. Penelitian ini dilakukan di Kelurahan Margomulyo Kabupaten Ngawi dengan pendekatan Cross sectional. Sampel dipilih dengan purposive sampling, total sampel berjumlah 276 responden. Uji statistik yang digunakan untuk menganalisa data penelitian adalah Uji Spearmen dengan SPSS 21. Hasil penelitian menunjukkan tidak ada hubungan antara variabel pegetahuan wus dengan variabel sikap deteksi dini kanker serviks. Penelitian ini dapat dijadikan sebagai acuan untuk menentukan intervensi keperawatan yang tepat dalam meningkatkan pengetahuan yang diharapkan merubah sikap para wanita usia subur terhadap deteksi dini kanker serviks
Pemanfaatan Koagulan Biji Asam Jawa Guna Memperbaiki Parameter BOD, COD, dan TSS Limbah Cair Industri Tahu
Authors: Yusuf Andi Mohamad , Ruhiyat Ratnaningsih , Hadisoebroto Rositayanti
Published: August 2022

Industri tahu menghasilkan limbah yang perlu diproses terlebih dahulu sebelum dibuang ke lingkungan. Terdapat beberapa koagulan organik yang dapat digunakan sebagai penurun parameter pencemar yang terdapat pada limbah tahu, salah satunya yaitu biji asam jawa. Biji asam jawa (Tamarindus indica) dapat dimanfaatkan untuk pengolahan limbah karena bijinya mengandung pati yang bersifat sebagai flokulan alami. Penelitian ini bertujuan menguji keefektivitasan biji asam jawa sebagai koagulan organik dalam mengolah air limbah tahu. Penelitian dilakukan dari bulan Agustus 2021 sampai Maret 2022 dengan pengambilan sampel air limbah tahu di Kalideres, Jakarta Selatan. Parameter yang akan dikurangi yaitu kekeruhan, TSS, COD, dan BOD. Hasil penelitian menunjukan bahwa biji asam jawa mampu mengurangi kekeruhan, TSS, COD, dan BOD di dosis 4 g/L dan pH 8 dengan parameter pencemar yang berhasil diturunkan yaitu kadar BOD diturunkan sebesar sebesar 82%, kadar COD diturunkan sebesar 82%, kadar TSS diturunkan sebesar 78%, dan kekeruhan diturunkan sebesar 84%.
The fossil vertebrata in the Department of Geology at Southampton University
Authors: Delair J. B.
Published: August 2022

The largest single collection of fossils in Hampshire is housed in the Department of Geology, Southampton University. Originally formed at the old Hartley Institute, the collection consists of a wide range of British and foreign specimens among which those from the typical Hampshire Basin formations understandably predominate. The present note relates to the vertebrate remains which form a significant proportion of the collection as a whole.
How to succeed in museums without really trying?
Authors: Shepherd T.
Published: August 2022

Hugh Torrens contributed this item by T. Shepherd which was originally published in 1916 in a publication entitled Yorkshire's Contribution to Science.
Board Characteristics and Research and Development of Listed Manufacturing Firms in Nigeria
Authors: Wisdom Okere , Grace Offiaeli Amarachuwku , Stephanie Ilo
Published: August 2022

The study evaluated the impact of board characteristics on the research and development of quoted manufacturing firms in Nigeria. Its objective was to assess the association between board characteristics and R&D in quoted manufacturing firms in Nigeria. The scope of the study was from 2011 to 2020, secondary data was adopted in this study, which was extracted from the corporate reports of the listed food-manufacturing firms in Nigeria. The study made use of a sample size of 10 manufacturing firms. The agency theory was adopted in the work. A panel ordinary least square regression was used to test for the relationship and impact of the variable and the results. The findings of the study show a positive correlation between board characteristics and R&D in listed food manufacturing firms in Nigeria. This study recommends that the manufacturing firms should not overlook the effect research and development have on the value creation of the firms as over time this would promote business sustainability.
A Színpadművészeti Stúdió története
Authors: Gara Márk
Published: August 2022

The Studio of Stage Arts was founded in 1928. The members of this group of artists belonged to the same generation and most of them were practical theater professionals joined by two excellent aesthetes. The purpose of my paper is to introduce the Studio, the aim of which was to develop the craft of stage directing in Hungarian theatre.
PENDEKATAN SIMULASI SISTEM DISKRIT DALAM MENGURANGI WAKTU TUNGGU ANTRIAN DENGAN PERBAIKAN SISTEM APPOINTMENT SCHEDULING
Authors: Dwi Putra Muhammad Irvan , Berlianty Intan , Soejanto Irwan , DwiAstanti Yuli
Published: August 2022

Rumah sakit merupakan dalam industri jasa dengan orientasi utama melayani pasien. PKU Muhammadiyah sebagai rumah sakit swasta di Yogyakarta melayani rawat jalan pada klinik gigi dengan rata-rata jumlah pasien 27 orang dengan rata-rat waktu tunggu 65 menit per hari. PKU Muhammadiyah Yogyakarta mampu implemtasi sistem appointment scheduling. sistem ini belum menampilkan estimasi kedatangan pasien yang berakibat waktu menjadi lama. Dalam penelitian menggunakan simulasi sistem diskrit sesuai sistem nyatanya dan dengan software simulasi Flexim 6 untuk mengetahui berbagai skenario. Output yang diperoleh dibandingkan pada sistem nyata. Pada setiap modelnya dibangun 6 skenario berbeda atas waktu antar kedatangan pasien. Skenario tertinggi diperolah pada model pertama yaitu waktu antar kedatangan antar pasien 16 per menit dan mengurangi waktu tunggu menjadi 31,2 menit. Dengan pedekatan ini optimasi diperoleh sebesar 52%.
Design and Implementation of Enhanced Security Model for Wireless Sensor Network on ARM Processor
Authors: K Sonwalkar Prakash , Kalmani Vijay
Published: August 2022

Due to the radio range of the network, suspicious transmission, unattended nature, and easier access, Wireless Sensor Networks are vulnerable to malicious users and physical attacks. Hence security is a must in these cases. A workable solution to these problems might be to create a WSN for a secure temperature sensing system. Sensors gather temperature measurements, which are then communicated to an advanced RISC microprocessor (ARM) using Wireless Fidelity (Wi-Fi) technology, which has been proven to transfer data accurately and reliably. The data is then stored in memory, controlled by the microprocessor. An ARM 9-based Samsung S3C2440 Controller running on the Linux operating system is used to achieve the functionality. The security system is incorporated using the host MCUs, and the temperature values are converted to digital form using the ARM processor’s ADC (S3C2440). The processor is connected to the console terminal through UART, which regularly sends data to the system. Security data is monitored and transferred to other Wi-Fi-equipped devices through a USB-based Wi-Fi module. The temperature readings are continuously monitored via this wireless sensor network. We perform the validation of our study through MATLAB simulations. We measure the sensor nodes’ total energy dissipated, throughput, and lifetime through MATLAB simulations. Over all in this research, we develop improved security in WSN system with application in ARM controller-based secured temperature monitoring system. This paper paves a direction toward further research in physical security in Wireless Sensor Networks.
O DNA como um novo dispositivo de armazenamento de dados
Authors: Contiliani Danyel Fernandes , Pereira Tiago Campos
Published: August 2022

A elevada produção global de informação digital torna urgente o aprimoramento das tecnologias atuais de armazenamento de dados, como dispositivos magnéticos, ópticos e eletrônicos, empurrandoas cada vez mais próximas ao abismo da obsolescência. Diante das inúmeras características que inviabilizam a capacidade de armazenamento de dados a longo prazo por estes dispositivos tradicionais, o DNA surge como um material durável, replicável, resistente, recuperável e com alta capacidade de armazenamento. Dados computacionais podem ser traduzidos em um sistema análogo ao código genético e armazenados, no formato de oligonucleotídeos, em células por meio do uso da maquinaria do sistema imune procariótico, CRISPR. A partir do sequenciamento genômico, tais informações podem ser decodificadas novamente à linguagem computacional e, portanto, reproduzidas. Assim, o DNA recording é uma solução promissora para problemas atuais da tecnologia da informação e uma aposta para a próxima geração de dispositivos de armazenamento de dados.
Modelo didático para compreender variações genéticas humanas
Authors: Lima Iasmin Souza , Santana Gabriella Almeida Santos de , Barbieri Felipe dos Santos , Fernandes Larissa , Coimbra Diego , Marques Cintia Rodrigues
Published: August 2022

O modelo didático exposto neste trabalho possibilita que graduandos de ciências biológicas e ciências da saúde possam entender melhor conceitos teóricos referentes aos mecanismos de transcrição e tradução. O modelo apresentado foi desenvolvido a partir de uma simulação envolvendo o gene da b globina e as mutações e polimorfismos relacionados à anemia falciforme. A atividade proposta tem a finalidade de demonstrar como a informação gênica contida na molécula de DNA é transcrita e traduzida, e de que forma uma mutação ou polimorfismo pode interferir na formação do produto final, a proteína.
INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON
Authors: TÜRKER ASLAN Hatice , ATEŞ Ömer
Published: August 2022

Age-related macular degeneration (AMD) is a non-recyclable visual disorder among elderly people worldwide and AMD is one of the leading causes of blindness. Former studies, interleukins were found to be effective in patients with AMD. This study’s object, the relationship of serum interleukin 17 with age-related macular degeneration was evaluated.

Interleukin 17 levels were measured by ELISA method using the blood sera of 100 patients diagnosed with age-related macular degeneration and 100 healthy individuals in the control group.

Acording to the results of the study, the differences between the patient and control groups of interleukin 17 levels was found statistically significant (p:0,001; p > 0,05). It was found that gender difference in patients did not affect interleukin 17 levels (p=0,649; p > 0,05).

In the study, there was a significant relationship between age-related macular degeneration and serum interleukin 17.
AN EXPLORATORY STUDY OF DETERMINANTS OF THE QUALITY OF MUNICIPAL SERVICE DELIVERY IN EKURHULENI
Authors: Moraba Ignitious
Published: August 2022

The City of Ekurhuleni is a major metropolitan municipality that provides essential municipal services 3, 178, 470 residents and ratepayers. The purpose of research was to determine the level of satisfaction of people who live and work in the City of Ekurhuleni with the quality of municipal services they are provided with routinely. The survey was conducted by gathering household-level information from 544 residents of Ekurhuleni. The level of satisfaction of respondents with the quality of municipal services was measured by using a matrix of indicators developed by Das, Das and Barman (2021:885-913) for conducting a similar assessment. A composite index developed by D’Inverno and De Witte (2020:1129-1141) was used as a benchmark for measuring the level of services rendered to people who live in the City. The main result of the survey was that 63.05% of people who took part in the survey expressed satisfaction with the quality of services that were rendered to people living in the City. The results showed that 36.95% of people in the survey were not happy with the quality of services rendered to people who live in the City. The survey revealed that satisfaction with services was influenced by the ability of employees of the City to resolve service-related queries promptly, a lengthy duration of residence in Ekurhuleni (11 years or longer), and being provided with accurate financial statements.
Problems of Development of Innovative Economy in Germany and Spain and Possible Ways of Their Solution
Authors: Morozova Ya. D.
Published: August 2022

The following article is focused on the issues of development of innovative economy based on statistics and sythesis of previously conducted scientific researches. These challenges are analysed through the case study of Germany and Spain as they represent different groups of countries in terms of innovation and feature various approaches to overcome the problems.Such problems as: inability to adapt to the objective trend to slow down the widespread introduction of innovations, underfunding of high-tech industries, lack of radical innovations, narrow scope of higher education specializations, lack of mechanisms to protect investors in innovative projects and inconsistency of legislation regulating innovative activity are considered typical for Germany. The issues of underestimation of the innovative potential of the state, lack of infrastructure and coordination between its facilities, high level of bureaucracy, insufficient training and inefficient use of resources are the ones that Spainish economy faces. Detection of the above listed challenges allows to develop recommendations to resolve the issues of German and Spanish innovative economics. Their expirience would to be useful in identifying the challenges of the current situation and in formulating development strategies for states with similar problems, including Russia.
Boiling Heat Transfer of Low GWP Refrigerants: A Review
Authors: Ray Sudish
Published: August 2022

The boiling heat transfer of low GWP (global warming potential) refrigerants, which are more environmentally benign, is studied in this work. Low GWP applications allow for greater freedom in the choice of suitable working fluids based on application and necessity. Human comfort demands increase as a result of the rapid pace of climate change in order to adapt to its negative effects. HVAC&R (Heating, Ventilation, Air Conditioning, and Refrigeration) is crucial for preserving the level of climate comfort in a closed space and its surrounds by using eco-friendly refrigerants. The purpose of this review is to provide a summary of significant studies on the application of low GWP refrigerants in boiling heat transfer, as well as a background on refrigerants and their many subtypes. Along with explaining the impacts of vpour quality, heat flux, and mass flux on pressure drop, this also discusses the implications of heat flux, mass flow, saturation temperature, and the heat transfer mechanism on the heat transfer coefficient.
Affordable cold storage for preservation of perishable agricultural products in the context of North Bengal
Authors: U. Das  , A. Mahapatra
Published: August 2022

A cold storehouse is the most effective system of conserving perishable vegetable quality like tomatoes, potatoes cabbage, eggplant carrot, etc., but its high cost deters relinquishment by the planter, smallholder, producer, and entrepreneurs. Several low-cost cooling devices have been developed, but they cannot maintain the recommended storehouse temperature. Various types of fruit and vegetables taste best when they're gathered completely ripe and also consumed or reused. Leafy vegetables and sauces also don't keep long after the crop. With fruit and vegetables from the home garden, speedy consumption and further processing are no problem, but consumers also want a certain shelf life in addition to good quality and full aroma for bought products. This pretense is a challenge to farmers for fruit and vegetable because the metabolism of the products continues indeed after the crop when gathered in the optimal condition, the quality of the gathered material decreases continuously - it loses taste and constituents and changes its appearance and thickness until it's at some point is no longer comestible. Perishable products deteriorate fleetly during the post-harvest chain. Thus, it is required to give an affordable cold storehouse system to enhance the quality and shelf life of the perishable agricultural products for rural as well as urban use. In the following acquaintance, the reader will learn how solar cold storehouses may be used for the preservation of perishable products and will be affordable to growers and smallholders, producers as well as entrepreneurs.
Optimization of Cutting parameters of AISI 1018 Low Carbon Mild steel in turning using green cutting fluid by Taguchi Method
Authors: S. Ghosh  , Mandal M.C. , K. Das  , N. Mondal  , A. Ray
Published: August 2022

The objective of this work is to optimize the response Cutting parameters (Tool wear and Material Removal Rate) of AISI 1018 Low carbon mild steel by Taguchi Method in straight turningprocess. We have taken speed, feed, depth of cut and types of cutting fluids as machining parameters with their three level values. In our study a commercial semi-synthetic cutting fluid (SSCF) and two vegetable based cutting fluids are used and values of response variables are analyzed to see if the performance of response machining parameters is increased by using Vegetable based cutting fluids for sustainable machining.For individual optimization,Taguchi‟s L9(34 ) orthogonal array and Analysis of Variance(ANOVA) are used. The optimum results are verified with the help of confirmation test
Pop-Up Book untuk Mendorong Minat Belajar Peserta Didik Kelas V
Authors: Iriani Astuti  , Endra Putra Raharja  , Asrul
Published: August 2022

Penelitian ini dilakukan dengan tujuan untuk mendeskripsikan pengaruh media pembelajaran pop-up book terhadap minat belajar peserta didik kelas V di SD Muhammadiyah Majaran. Pada penelitian ini, penelitian yang digunakan adalah penelitian Kuantitatif dengan jenis penelitian Eksperimen, dengan desain Pre-Exsperimental Design yaitu penelitian yang hanya menggunakan satu kelompok eksperimen dan tidak memiliki kelompok kontrol. Populasi pada penelitian ini adalah seluruh peserta didik SD Muhammadiyah Majaran Kabupaten Sorong yang berjumlah 56 peserta didik dengan sampel kelas V yang berjumlah 12 peserta didik. Penelitian ini menggunakan teknik non tes dengan istrumen yang digunakan yaitu angket pernyataan minat belajar, lembar observasi guru, lembar observasi peserta didik, RPP, media pembelajaran Pop-Up Book dan dokumentasi. Dari analisis data diperoleh uji normalitas Shapiro Wilk yaitu 0,145 untuk pre-test dan 0,162 untuk post-test. Hasil uji N-Gain menunjukkan bahwa bahwa persentase nilai mean statistik adalah 60,4323 dan nilai tersebut berada dalam kategori cukup efektif (rentang nilai 56-75). Hasil data uji One Sampel t-Test menunjukkan bahwa nilai T yaitu 5,217 dengan df yaitu 11 yang berarti terdapat pengaruh positif media pembelajaran Pop-Up Book terhadap minat belajar peserta didik pada materi perubahan wujud benda.
Studi Banding Implementasi Metode Hidden Markov Model dalam Pengenalan Tulisan Tangan
Authors: Miftahul Amri Muhammad
Published: August 2022

Hidden Markov Model (HMM) adalah model distribusi yang menghasilkan observasi yang bergantung pada keadaan pokok dan tidak dapat diamati (tersembunyi) pada Proses Markov. Metode pemodelan ini dapat diterapkan pada berbagai aplikasi secara fleksibel untuk data time series univariat dan multivariat, terutama untuk series dengan nilai diskrit, termasuk series pengelompokan dan series perhitungan. [1] HMM dapat digunakan untuk memprediksi kemungkinan demonstrasi massa, mengenali ekspresi wajah seseorang, seismokardiograf, dsb. Penggunaan metode HMM untuk pengenalan tulisan tangan telah sering dilakukan. Namun dari berbagai penelitian yang telah dilakukan, terdapat perbedaan metode ekstraksi fitur maupun metode pelatihan. Paper ini bertujuan untuk mengetahui metode dan parameter dari HMM yang menghasilkan performa terbaik dalam pengenalan tulisan tangan. Berdasarkan hasil perbandingan penelitian yang telah dilakukan sebelumnya [7, 8, 9, 10, 11, 12], didapatkan kombinasi metode yang paling optimal adalah ekstraksi 24 fitur meliputi kerapatan piksel hitam, posisi vertikal & horizontal piksel hitam, serta arah (kecekungan) piksel dengan batas ambang adaptif. Kemudian nilai tersebut diolah dengan menggunakan kombinasi planar HMM (hybrid) dan advanced HMM yang bersifat adaptif. Semakin banyak jumlah state dan sampel data, maka akurasi pengenalan akan semakin baik. Namun, waktu komputasi juga akan semakin lama. Maka, jumlah state dan sampel yang paling optimal perlu ditentukan melalui simulasi dan eksperimen.
Inhibition of itch by neurokinin 1 receptor (Tacr1) -expressing ON cells in the rostral ventromedial medulla in mice
Authors: Follansbee Taylor , Domocos Dan , Nguyen Eileen , Nguyen Amanda , Bountouvas Aristea , Velasquez Lauren , Iodi Carstens Mirela , Takanami Keiko , Ross Sarah E , Carstens Earl
Published: August 2022

The rostral ventromedial medulla (RVM) is important in descending modulation of spinal nociceptive transmission, but it is unclear if the RVM also modulates spinal pruriceptive transmission. RVM ON cells are activated by noxious algesic and pruritic stimuli and are pronociceptive. Many RVM-spinal projection neurons express the neurokinin-1 receptor (Tacr1), and ON-cells are excited by local administration of substance P (SP). We hypothesized that Tacr1-expressing RVM ON cells exert an inhibitory effect on itch opposite to their pronociceptive action. Intramedullary microinjection of SP significantly potentiated RVM ON cells and reduced pruritogen-evoked scratching while producing mild mechanical sensitization. Chemogenetic activation of RVM Tacr1-expressing RVM neurons also reduced acute pruritogen-evoked scratching. Optotagging experiments confirmed RVM Tacr1-expressing neurons to be ON cells. We conclude that Tacr1-expressing ON cells in RVM play a significant role in the modulation of pruriceptive transmission.
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy
Authors: Boddupalli Chandra Sekhar , Nair Shiny , Belinsky Glenn , Gans Joseph , Teeple Erin , Nguyen Tri-Hung , Mehta Sameet , Guo Lilu , Kramer Martin L , Ruan Jiapeng , Wang Honggge , Davison Matthew , Kumar Dinesh , Vidyadhara DJ , Zhang Bailin , Klinger Katherine , Mistry Pramod K
Published: August 2022

Background:

Neuronopathic Gaucher disease (nGD) is a rare neurodegenerative disorder caused by biallelic mutations in GBA and buildup of glycosphingolipids in lysosomes. Neuronal injury and cell death are prominent pathological features; however, the role of GBA in individual cell types and involvement of microglia, blood-derived macrophages, and immune infiltrates in nGD pathophysiology remains enigmatic.

Methods:

Here, using single-cell resolution of mouse nGD brains, lipidomics, and newly generated biomarkers, we found induction of neuroinflammation pathways involving microglia, NK cells, astrocytes, and neurons.

Results:

Targeted rescue of Gba in microglia and neurons, respectively, in Gba-deficient, nGD mice reversed the buildup of glucosylceramide (GlcCer) and glucosylsphingosine (GlcSph), concomitant with amelioration of neuroinflammation, reduced serum neurofilament light chain (Nf-L), and improved survival. Serum GlcSph concentration was correlated with serum Nf-L and ApoE in nGD mouse models as well as in GD patients. Gba rescue in microglia/macrophage compartment prolonged survival, which was further enhanced upon treatment with brain-permeant inhibitor of glucosylceramide synthase, effects mediated via improved glycosphingolipid homeostasis, and reversal of neuroinflammation involving activation of microglia, brain macrophages, and NK cells.

Conclusions:

Together, our study delineates individual cellular effects of Gba deficiency in nGD brains, highlighting the central role of neuroinflammation driven by microglia activation. Brain-permeant small-molecule inhibitor of glucosylceramide synthase reduced the accumulation of bioactive glycosphingolipids, concomitant with amelioration of neuroinflammation involving microglia, NK cells, astrocytes, and neurons. Our findings advance nGD disease biology whilst identifying compelling biomarkers of nGD to improve patient management, enrich clinical trials, and illuminate therapeutic targets.

Funding:

Research grant from Sanofi; other support includes R01NS110354.
A novel steganography method for binary and color halftone images
Authors: Çiftci Efe , Sümer Emre
Published: August 2022

Digital steganography is the science of establishing hidden communication on electronics; the aim is to transmit a secret message to a particular recipient using unsuspicious carriers such as digital images, documents, and audio files with the help of specific hiding methods. This article proposes a novel steganography method that can hide plaintext payloads on digital halftone images. The proposed method distributes the secret message over multiple output copies and scatters parts of the message randomly within each output copy for increased security. A payload extraction algorithm, where plain carrier is not required, is implemented and presented as well. Results gained from conducted objective and subjective tests prove that the proposed steganography method is secure and can hide large payloads.
Social calls in humpback whale mother-calf groups off Sainte Marie breeding ground (Madagascar, Indian Ocean)
Authors: Saloma Anjara , Ratsimbazafindranahaka Maevatiana N. , Martin Mathilde , Andrianarimisa Aristide , Huetz Chloé , Adam Olivier , Charrier Isabelle
Published: August 2022

Humpback whales (Megaptera novaeangliae) use vocalizations during diverse social interactions or activities such as foraging or mating. Unlike songs produced only by males, social calls are produced by all types of individuals (adult males and females, juveniles and calves). Several studies have described social calls in the humpback whale’s breeding and the feeding grounds and from different geographic areas. We aimed to investigate for the first time the vocal repertoire of humpback whale mother-calf groups during the breeding season off Sainte Marie island, Madagascar, South Western Indian Ocean using data collected in 2013, 2014, 2016, and 2017. We recorded social calls using Acousonde tags deployed on the mother or the calf in mother-calf groups. A total of 21 deployments were analyzed. We visually and aurally identified 30 social call types and classified them into five categories: low, medium, high-frequency sounds, amplitude-modulated sounds, and pulsed sounds. The aural-visual classifications have been validated using random forest (RF) analyses. Low-frequency sounds constituted 46% of all social calls, mid-frequency 35%, and high frequency 10%. Amplitude-modulated sounds constituted 8% of all vocalizations, and pulsed sounds constituted 1%. While some social call types seemed specific to our study area, others presented similarities with social calls described in other geographic areas, on breeding and foraging grounds, and during migrating routes. Among the call types described in this study, nine call types were also found in humpback whale songs recorded in the same region. The 30 call types highlight the diversity of the social calls recorded in mother-calf groups and thus the importance of acoustic interactions in the relationships between the mother and her calf and between the mother-calf pair and escorts.