bluuebunny/crossref_metadata_2025 huggingface dataset:
Overview of moment-tensor inversion of microseismic events
Authors: Eyre Thomas S. , van der Baan Mirko
Published: July 2015

Understanding the source mechanisms of microseismic events is important for understanding the fracturing behavior and evolving stress field within a reservoir, knowledge of which can help to improve production and minimize seismic risk. The most common method for calculating the source mechanisms is moment-tensor inversion, which can provide the magnitudes, modes, and orientations of fractures. An overview of three common methods includes their advantages and limitations: the first-arrival polarity method, amplitude methods, and the full-waveform method. The first-arrival method is the quickest to implement but also the crudest, likely producing the least reliable results. Amplitude methods are also relatively simple but can better constrain the inversion because of the increased number of observations, especially those using S/P amplitude ratios. Full-waveform methods can provide results of very good quality, including source-time functions, but involve much more complex and expensive calculations and rely on accurate seismic-velocity models.
Reservoir stress from microseismic source mechanisms
Authors: Staněk František , Jechumtálová Zuzana , Eisner Leo
Published: July 2015

Microseismic monitoring allows an inversion of advanced parameters that characterize a reservoir such as a stress-field orientation in addition to usual locations and source mechanisms. By inverting source mechanisms of microseismic events induced by hydraulic fracturing in a shale reservoir and using those mechanisms, one can obtain the stress field. Stress-field inversions using source mechanisms inverted from manually and automatically picked P-wave arrival amplitudes were compared. Stress fields determined from manual and automated P-wave arrival amplitudes are consistent. This implies that one can use the automated inversion of source mechanisms to reliably determine the stress field. The resulting stress fields are stable and consistent with the regional stress field measured in the region on the World Stress Map. Obtained maximum regional stress in the vertical direction, which is typical for most sedimentary basins, and a maximum horizontal stress oriented approximately 75° from the direction of the drilled lateral sections of wells. Finally, an inverted-shape ratio is used to plot Mohr diagrams that illustrate the most likely fault planes activated through hydraulic fracturing.
Microseismic monitoring of a hydraulic-fracturing operation in a CBM reservoir: Case study in the Cerrejón Formation, Cesar-Ranchería Basin, Colombia
Authors: Rodríguez-Pradilla Germán
Published: July 2015

Passive-seismic monitoring techniques were implemented for source characterization of microseismic events generated during a hydraulic-fracturing operation in a coalbed-methane (CBM) reservoir in Colombia. Hydraulic fracturing is a common stimulation technique performed to increase the permeability and productivity of conventional and unconventional reservoirs. Its use has increased in the last decade in several countries, including Colombia, and it is expected to keep rising in the following years. The success of a hydraulic-fracturing operation can be assessed in different ways, of which microseismic monitoring is the most common technique. This method can be implemented using surface or downhole seismometers and allows the characterization of microseismic events associated with the fractures generated. A workflow for passive-seismic data analysis was developed to characterize microseismic events (i.e., hypocenter location and source-mechanism analysis) from data acquired with surface stations and to obtain important parameters for a hydraulic-fracturing design such as the stimulated reservoir volume (SRV), orientation, and anisotropy of horizontal stresses and a discrete fracture network (DFN). This workflow was implemented in a case study in Colombia in which a coalbed-methane reservoir in Cesar-Ranchería Basin was stimulated by hydraulic fracturing. Surface seismometers were deployed around the wellhead to monitor the microseismicity generated and to estimate all the design parameters of the stimulation.
Microseismic geomechanics of hydraulic-fracture networks: Insights into mechanisms of microseismic sources
Authors: Maxwell S. C. , Chorney D. , Goodfellow S. D.
Published: July 2015

Microseismic interpretation of hydraulic fracturing requires an understanding of the mechanism of the microseismic sources. Quantitative geomechanical models can predict microseismicity for quantitative comparison with field data and can be used to reconcile 3D seismic earth models, fracture engineering, and fracture monitoring. Because microseismicity represents only one component of the geomechanical response to hydraulic fracturing, a microseismic geomechanics framework can provide insights into the connection with the fracture network. During hydraulic fracturing, microseismicity can be induced by both fluid pressure and stress mechanisms, resulting in wet events directly associated with the fracture network and remote dry events. Accurate interpretation of the hydraulic-fracture characteristics requires distinguishing identification of dry microseismicity not in hydraulic connection with the stimulated fracture network. Predictive microseismic geomechanical models also can be used to infer the primary, conductive hydraulic-fracture networks and to run scenario testing to improve engineering design.
Estimation and interpretation of high-confidence microseismic source mechanisms
Authors: Diller David E. , Shuck Ted , Fish Barry
Published: July 2015

Some of the advantages of surface microseismic monitoring can be examined to suggest ways in which those advantages can improve the use and interpretation of microseismic results. In particular, surface microseismic monitoring provides an opportunity to determine the source mechanism for most events, and methods are available that can increase the confidence in those results. One method for determining microseismic source mechanism is image-domain pattern recognition (IDPR), which is more suitable to the relatively noisy environment of surface microseismic monitoring than the classic time-domain methods are. One drawback that must be addressed is that accurate image-domain pattern recognition requires the use of 3D velocity corrections. Finally, microseismic events with high-confidence locations and source mechanisms can be used to directly construct discrete fracture networks (DFN).
Microseismic shearing driven by hydraulic-fracture opening: An interpretation of source-mechanism trends
Authors: Rutledge James , Yu Xin , Leaney Scott
Published: July 2015

Hydraulic-fracture microseismicity is interpreted for cases in which persistent dip-slip or strike-slip mechanisms exhibit shear planes prevalently aligned close to the principal stress direction. Explaining the preferential alignment in terms of stress changes driven by elevated pore pressure on a Mohr diagram is difficult. Instead, it is proposed that the microseismic shearing is driven primarily by the strain of hydraulic-fracture opening. The interpretation is based on the analog of structures and deformation commonly associated with natural joint growth in layered rock. Specifically, by considering the alternate, horizontal nodal plane as the slip plane for the aligned dip-slip events, one can associate the shearing with a vertical hydraulic fracture stepping over or jogging along bedding planes and generating bedding-plane slip. For the aligned strike-slip events, it is proposed that the critical shearing is generated by breakup of the hydraulic fracture into en echelon fringe fractures near bedding surfaces. In both cases, the shearing represents a tearing mode (mode III) in which the microseismicity highlights the deformation at and near bedding boundaries as the hydraulic fracture rips through or along layer interfaces.
Mapping and validating lineaments
Authors: Niccoli Matteo
Published: July 2015

Data enhancement can help to emphasize edges that correspond to contrasts in acoustic impedance, magnetic susceptibility, or bulk density. Such contrasts often indicate the presence of important geologic boundaries. Emphasizing the edges can help with mapping and interpretation of those boundaries.
Reviews
Authors: Liu Lanbo , Taylor Patrick , Moon Wooil M.
Published: July 2015

The Magnetotelluric Method: Theory and Practice, edited by Alan D. Chave and Alan G. Jones, ISBN 978-0-521-81927-5, 2012, Cambridge University Press, 570 p., US $159.99. Application Manual of Geophysical Methods to Engineering and Environmental Problems, edited by the Society of Exploration Geophysicists of Japan, ISBN 907-3834880, ISBN 978-9-07383-488-0, 2014, EAGE, 664 p., US $399.78. Advanced Data Assimilation for Geosciences: Lecture Notes of the Les Houches School of Physics: Special Issue, June 2012 (Lecture Notes of the Les Houches Summer School), edited by Éric Blayo, Marc Bocquet, Emmanuel Cosme, and Leticia F. Cugliandolo, ISBN 978-0-198-72384-4, 2015, Oxford University Press, 2015, 584 p., US $69.95.
SEAM Update
Authors: Oristaglio Michael
Published: July 2015

Rocks in the earth's crust and mantle exhibit macroscopic seismic anisotropy — a phenomenon in which the local speed of a seismic wave depends on the direction in which it travels. Modeling the seismic anisotropy of fractured shale reservoirs in sedimentary basins was a primary goal of the Barrett Unconventional Model, the first model to be completed in SEAM Phase II. Classic seismic data sets for the Barrett Model were distributed to consortium members in the fall of 2014 and will be available to the public within two years after the Phase II consortium ends in March 2016. This article describes how seismic anisotropy is built into the Barrett Model. True to the model's name, the representation is somewhat unconventional.
Recommendations Using Information from Multiple Association Rules: A Probabilistic Approach
Authors: Ghoshal Abhijeet , Menon Syam , Sarkar Sumit
Published: July 2015

Business analytics has evolved from being a novelty used by a select few to an accepted facet of conducting business. Recommender systems form a critical component of the business analytics toolkit and, by enabling firms to effectively target customers with products and services, are helping alter the e-commerce landscape. A variety of methods exist for providing recommendations, with collaborative filtering, matrix factorization, and association-rule-based methods being the most common. In this paper, we propose a method to improve the quality of recommendations made using association rules. This is accomplished by combining rules when possible and stands apart from existing rule-combination methods in that it is strongly grounded in probability theory. Combining rules requires the identification of the best combination of rules from the many combinations that might exist, and we use a maximum-likelihood framework to compare alternative combinations. Because it is impractical to apply the maximum likelihood framework directly in real time, we show that this problem can equivalently be represented as a set partitioning problem by translating it into an information theoretic context—the best solution corresponds to the set of rules that leads to the highest sum of mutual information associated with the rules. Through a variety of experiments that evaluate the quality of recommendations made using the proposed approach, we show that (i) a greedy heuristic used to solve the maximum likelihood estimation problem is very effective, providing results comparable to those from using the optimal set partitioning solution; (ii) the recommendations made by our approach are more accurate than those made by a variety of state-of-the-art benchmarks, including collaborative filtering and matrix factorization; and (iii) the recommendations can be made in a fraction of a second on a desktop computer, making it practical to use in real-world applications.
The Integration of Psychological and Network Perspectives in Organizational Scholarship
Authors: Casciaro Tiziana , Barsade Sigal G. , Edmondson Amy C. , Gibson Cristina B. , Krackhardt David , Labianca Giuseppe (Joe)
Published: July 2015

Although multiple disciplines have been applied to the study of organizations, organizational research is rarely interdisciplinary in the sense of two or more disciplines being linked in the joint analysis of organizational phenomena. The articles in this special issue illustrate the kinds of insights that can be gained by moving from a purely disciplinary perspective on organizational behavior to an interdisciplinary perspective that considers network phenomena and psychological phenomena as intertwined in organizational life. The advances of this special forum notwithstanding, large swaths of network–psychological integration are still largely unexplored in organizational research. We highlight a subset of particularly promising avenues for further interdisciplinary exploration. We also observe that the two research programs have developed into distinct paradigms, making interdisciplinary discourse challenging, and offer suggestions toward a greater integration and collaboration across the two research communities.
Petrology and Geochemistry of Chaleh Kaftar Granites, Northeast of Torud
Authors: Nazemi Ebrahim , Tahriri Fatemeh , Mostafa baratyan Mostafa
Published: July 2015

According to petrographic and geochemical studies on the Chaleh Kaftar granitoids in Torud, these granitoids have an alkaline composition range including feldspar granite, quartz monzonite, and syenite. The dominant texture of the region is granular. Rock samples are of calc-alkaline nature and are situated along the calc-alkaline series. The rocks in the region are enriched with large ion lithophile elements (LILE) such as Rb, K and Th. Elements with a high ionic strength or high field strength elements (HFSE) such as Ti, P, Nb show depletion, which is the characteristic of volcanic arc granites. Such granites are formed as a result of the processes associated with subduction zones. By moving from the left to the right of spider diagrams a negative slope is observed. The zigzag pattern of these diagrams also reflects the crustal contamination of these granites. Light rare earth elements are found to be richer than heavy rare earth elements in the region. These granitoids belong to active continental margin arc environments.
The Structural Dynamic Analysis of Embankment Dams Using Finite Difference and Finite Element Methods
Authors: Shekarbeigi Mehdi , Sharafi Hasan
Published: July 2015

This study is aimed to provide a structural dynamic analysis of embankment dams using numerical methods. The dynamic analyses are performed based on the time histories by applying accelerogram of several real earthquakes. For a dynamic analysis, it is initially performed a comprehensive study of the characteristics and coordinates of the earthquake accelerograms. The numerical analysis method is established on the comparison of the results of the numerical finite difference (FDM) and finite element (FEM) methods. This paper constitutes two-dimensional numerical plane-strain dynamic analyses in time domain. The focus of this research is to examine the amplified impacts ​​of accelerations and the lateral (horizontal) and vertical (settlement) displacements due to earthquake loading. All the models are undergone the static analysis, followed by dynamic analysis, and after the initial static equilibrium, they are placed under dynamic loading. It is presented a case study on Jamishan Embankment Dam in Kermanshah Province, Iran. The analytical results indicate that there is a good agreement between both numerical methods; however, there are some rare cases with contradictory results, majorly due to the slight differences of fundamental calculations or the definitions of damping ratio and boundary conditions in both numerical methods. Nevertheless, the results illustrate that the free board height of the Jamishan Dam determined by the consultant engineer is responsive to the most critical conditions and prevents the water overflow from the dam in case of strong vibrations.
The sense of sight words
Authors: Bishopis Jennifer
Published: July 2015

This article follows on from June's Focus article by exploring ways of teaching high frequency words while accelerating children's reading and writing progress, using the word ‘was’ as a relevant example.
Finding father figures
Authors: Gouldsboro Julia
Published: July 2015

It is a question and problem that just refuses to go away, just how do you increase the number of men working in childcare? Is it the sector or society at large that needs to change its deeply held attitudes.
Developing essential early years skills outdoors
Authors: Sargent Marianne
Published: July 2015

Our task in the early years is to provide learning experiences that encourage young children to explore concepts and to practise skills through self-directed activity and play involving hands-on investigation.
Making a real mess of it
Authors: Gascoyne Sue
Published: July 2015

Sue Gascoyne explores the use of messy play in Play Therapy, and suggests that by understanding its value and hidden meaning, the same benefits can be reaped in early years sand and water trays.
Advanced approaches to handling dogs in practice
Authors: Hedges Stephanie
Published: July 2015

There have been ground breaking advances in the field of dog training and behaviour modification in the last 20 years. Traditional theories advocating the use of ‘dominance’ to control dog behaviour have given way to ‘force free’ techniques that rely on understanding and changing the dog's motivation. An entirely hands off approach is not realistic in all cases in veterinary practice. However routine application of contemporary behavioural principles to the approach and handling of dogs in practice can improve welfare and reduce defensive aggression for the benefit of both patient and staff alike.
Impact of Gujjar Rehabilitation Programme on the group size of Asian elephants (Elephas maximus) in Rajaji National Park, North-West India
Authors: JOSHI RITESH
Published: July 2015

Joshi R. 2015.Impact of Gujjar Rehabilitation Programme on the group size of Asian elephants (Elephas maximus) in Rajaji National Park, North-West India. Biodiversitas 16: 188-195. A comparative study has been done to assess the impact of the GujjarRehabilitation Programme on the groupâ€™s size of Asian elephants (Elephas maximus) in Rajaji National Park, north-west India. Fieldsurveys were carried outbefore the Gujjarâ€™s rehabilitation during 1999-2001 and after the Gujjarâ€™s rehabilitation during 2006-2008 inChilla and Haridwar forest ranges of the park. A total of 833 groups of elephants were sighted, varying from 2-5 (meanvalueÂ±SD=28.5Â±24.7) to 21-25 animals (mean valueÂ±SD=8.2Â±4.6). The number of groups sighted in Haridwar forest after the Gujjarsâ€™rehabilitation were significantly low in summer and winter as compared before the Gujjarsâ€™ rehabilitation. However, the number ofgroups sighted in Chilla forest before and after the Gujjarsâ€™ rehabilitation in both the seasons was found to be same. Results indicatedthat elephantâ€™s groupâ€™s size and movement was shrinking/reducing in Haridwar forest, however, in Chilla forest it was found to beslightly expanding/increasing. The impact of Gujjar Rehabilitation Programme has not brought any drastic change in restoring the largerpopulation of elephants and in increasing their groupâ€™s size, however, this has increased the frequent movement and activities ofelephants within their home range. Restoration of large fragmented forest stretches/corridors for elephantâ€™s migration and habitatmanagement are of paramount importance in providing elephants a wider way to move across entire landscape in large herds. Asincrease in human population in the nearby areas and developmental activities, with increase in vehicle traffic pressure on nationalhighways and railway track existing across the park were found to be creating negative impacts on the overall movement of large groupsof the elephants.
Delayed Administration and Contraindicated Drugs Place Hospitalized Parkinson's Disease Patients at Risk; Doxorubicin Liposomal Mix-up; Avoid Mix-ups between Hydroxyprogesterone and Medroxyprogesterone
Authors: Cohen Michael R. , Smetzer Judy L.
Published: July 2015

These medication errors have occurred in health care facilities at least once. They will happen again—perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided. You should consider publishing accounts of errors in your newsletters and/or presenting them at your inservice training programs.

Your assistance is required to continue this feature. The reports described here were received through the Institute for Safe Medication Practices (ISMP) Medication Errors Reporting Program. Any reports published by ISMP will be anonymous. Comments are also invited; the writers' names will be published if desired. ISMP may be contacted at the address shown below.

Errors, close calls, or hazardous conditions may be reported directly to ISMP through the ISMP Web site ( www.ismp.org ), by calling 800-FAIL-SAFE, or via e-mail at ismpinfo@ismp.org . ISMP guarantees the confidentiality and security of the information received and respects reporters' wishes as to the level of detail included in publications.
Garcinia Cambogia–Induced Acute Hepatitis; Varenicline-Induced Parkinsonism; Resistant Hypocalcemia after Zoledronic Acid Administration; Zonisamide-Induced Acute Kidney Injury; Psychosis Associated with Guanfacine
Authors: Mancano Michael A.
Published: July 2015

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers.
Lenvatinib and Palbociclib
Authors: Solimando Dominic A. , Waddell J. Aubrey
Published: July 2015

The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases.
Montelukast: Chronic Urticaria
Authors: Generali Joyce A. , Cada Dennis J.
Published: July 2015

This Hospital Pharmacy feature is extracted from Off-Label Drug Facts, a publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration. This new guide to the literature enables the health care professional or clinician to quickly identify published studies on off-label uses and determine if a specific use is rational in a patient care scenario. References direct the reader to the full literature for more comprehensive information before patient care decisions are made. Direct questions or comments regarding Off-Label Drug Uses to jgeneral@ku.edu .
Descriptive Analysis of Patient Readmissions within 60 Days Due to Medication-Related Events
Authors: Thomas Julin , Coralic Aida , Ruegger Melanie , Thompson-Moore Nathaniel
Published: July 2015

Background

Hospital readmissions have become a marker for quality health care. Readmissions secondary to failures of the medication use process are poorly documented and underrecognized. Objective: To identify the incidence of readmissions related to the medication use process and identify associated patient- and therapy-related risk factors.

Methods

A prospective observational cohort study including patients discharged from an acute care medicine unit and readmitted within 60 days. The primary outcome was percentage of readmissions related to drug-related problems (DRPs) as defined by Pharmaceutical Care Network Europe (PCNE). Secondary outcomes included classification of problems using PCNE criteria, type and extent of pharmacist involvement in patient care, and identification of variables associated with a readmission related to a DRP.

Results

One hundred patients provided informed consent and were included for analysis. A DRP associated with readmission was identified in 64 patients. Sixty-one percent were classified as a potential problem with effect or lack of effect of pharmacotherapy. Patients who had a pharmacy consult were less likely to have a DRP (27% vs 47%; P = .04), and patients who missed follow-up appointments were more than 3 times as likely to have a DRP (20% vs 4%; P = .03). Presence of a pharmacy consult (odds ratio [OR], 0.38; 95% CI, 0.15–0.99; P = .05) and missed follow-up appointments (OR, 5.63; 95% CI, 1.52–20.86; P = .01) remained significant in a multivariate regression model.

Conclusion

DRPs were frequent in patients who were readmitted within 60 days. Clinical pharmacist involvement in care and support for appropriate patient follow-up may reduce unnecessary admissions.
Edoxaban
Authors: Cada Dennis J. , Baker Danial E. , Ingram Kyle
Published: July 2015

Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are sent in print and are also available on-line. Monographs can be customized to meet the needs of a facility. A drug class review is now published monthly with The Formulary Monograph Service. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. For more information about The Formulary Monograph Service, call The Formulary at 800-322-4349. The July 2015 monograph topics are ivabradine, dinutuximab, glycopyrronium bromide/indacaterol, patriromer, and idarucizumab. The Safety MUE is on ivabradine.
Approvals, Submission, and Important Labeling Changes for US Marketed Pharmaceuticals
Authors: Baker Danial E.
Published: July 2015

This monthly feature will help readers keep current on new drugs, new indications, dosage forms, and safety-related changes in labeling or use. Efforts have been made to ensure the accuracy of this information; however, if there are any questions, please let me know at danial.baker@wsu.edu .
Additional benefit of higher dose green tea in lowering postprandial blood glucose
Authors: Lahirin Rita , Permadhi Inge , Mudjihatini Ninik , Ridwan Rahmawaty , Sugianto Ray
Published: July 2015

Background: Green tea contains catechins that have inhibitory effects on amylase, sucrase, and sodium-dependent glucose transporter (SGLT) which result in lowering of postprandial blood glucose (PBG). This beneficial effect has been widely demonstrated using the usual dose (UD) of green tea preparation. Our study was aimed to explore futher lowering of PBG using high dose (HD) of green tea in healthy adolescents.
Methods: 24 subjects received 100 mL infusion of either 0.67 or 3.33 grams of green tea with test meal. Fasting, PBG at 30, 60, 120 minutes were measured. Subjects were cross-overed after wash out. PBG and its incremental area under the curve (IAUC) difference between groups were analyzed with paired T-test. Cathecin contents of tea were measured using high-performance liquid chromatography (HPLC).
Results: The PBG of HD group was lower compared to UD (at 60 minutes =113.70 ± 13.20 vs 124.16 ± 8.17 mg/dL, p = 0.005; at 120 minutes = 88.95 ± 6.13 vs 105.25 ± 13.85 mg/dL, p < 0.001). The IAUC of HD was also found to be lower compared to UD (2055.0 vs 3411.9 min.mg/dL, p < 0.001).
Conclusion: Additional benefit of lowering PBG can be achieved by using higher dose of green tea. This study recommends preparing higher dose of green tea drinks for better control of PBG.
Plants and herbs for therapy of diabetes
Authors: Pramono Laurentius A.
Published: July 2015

[No abstract available]
Paternal involvement in childcare: how can it be classified and what are the key influences?
Authors: Norman Helen
Published: July 2015

Establishing a clear definition of ‘paternal involvement’ is important in light of debates about what the concept means and how it might be measured. The debates about how to conceptualise ‘paternal involvement’ in childcare are reviewed in the first section of this article. I demonstrate how Lamb et al’s (1987) three dimensions of paternal involvement – accessibility, engagement and responsibility – continue to provide a comprehensive way of summarising a plethora of parental activities that are not bound by time, locality or age of child. The second section of this article discusses some of the key policy, workplace and individual factors that interact to shape and influence the three dimensions of involvement. Using Sen’s (1992) capabilities framework, I argue that while fathers may have the motivation and desire to be an involved parent, structural and individual factors often hinder their capabilities to be involved.
Legitimidad en el Gobierno Universitario: Una Nueva Tipología
Authors: Bernasconi Andres , Clasing Paula
Published: July 2015

Presentamos una tipología de formas de legitimidad de la autoridad universitaria, basada en la conocida clasificación de Max Weber de los tipos de autoridad política de acuerdo a la clase de legitimidad típicamente invocada por el que posee autoridad. Ella se adapta y expande al ámbito del gobierno universitario tomando como referencia la literatura especializada sobre modelos de gobierno universitario, con el apoyo además de los datos obtenidos de entrevistas a ex directivos universitarios a quienes interrogamos acerca de sus experiencias en sus cargos de autoridad. Nuestra tipología reconoce seis formas de legitimidad de la autoridad universitaria: la tradicional, que se divide en dos formas, académica y administrativa, la racional burocrática, que también tiene dos modalidades, la gerencial y la legalista, y luego las formas política y carismática. Para reforzar las distinciones entre los tipos de legitimidad propuestos, y ensayar una posible traducción de ellos en diseños susceptibles de investigación empírica, presentamos también un ejercicio de operacionalización de la tipología en variables e hipótesis.
Modellbasierte Analyse und Bewegungsplanung für das BionicKangaroo
Authors: Graichen Knut , Hentzelt Sebastian , Hildebrandt Alexander , Kärcher Nadine , Gaißert Nina , Knubben Elias
Published: July 2015

Der Beitrag beschreibt die Modellbildung, Analyse und Bewegungsplanung für das BionicKangaroo, das im Rahmen des Festo Bionic Learning
Networks entwickelt wurde. Zunächst wird auf die Modellierung eingegangen und die prinzipielle Machbarkeit und Stabilisierbarkeit des
Hüpfzyklus anhand eines modellprädiktiven Regelungsansatzes numerisch untersucht. Der eigentliche Reglerentwurf gliedert sich in die
modellbasierte Regelung der Flug- und Bodenphase. Eine zusätzliche Schaltbedingung verbindet die Flug- und Bodenphase miteinander und
initiiert den nächsten Hüpfzyklus durch das Abdrücken vom Boden.
Representation stability for homotopy groups of configuration spaces
Authors: Kupers Alexander , Miller Jeremy
Published: July 2015

We prove that the dual rational homotopy groups of the configuration spaces of a 1-connected manifold of dimension at least 3 are uniformly representation stable in the sense of [6], and that their derived dual integral homotopy groups are finitely generated as

𝖥𝖨

{{\mathsf{FI}}}

-modules in the sense of [4]. This is a consequence of a more general theorem relating properties of the cohomology groups of a 1-connected co-

𝖥𝖨

{{\mathsf{FI}}}

-space to properties of its dual homotopy groups. We also discuss several other applications, including free Lie and Gerstenhaber algebras.
No universal group in a cardinal
Authors: Shelah Saharon
Published: July 2015

For many classes of models, there are universal members in any cardinal λ which “essentially satisfies GCH, i.e., λ = 2<λ,” in particular for the class of models of a complete first-order T (well, if at least λ > |T|). But if the class is “complicated enough”, e.g., the class of linear orders, we know that if λ is “regular and not so close to satisfying GCH”, then there is no universal member. Here, we find new sufficient conditions (which we call the olive property), not covered by earlier cases (i.e., fail the so-called SOP4). The advantage of those conditions is witnessed by proving that the class of groups satisfies one of those conditions.
Weighted a priori estimates with powers of the distance function for elliptic equations
Authors: Toschi Marisa
Published: July 2015

Let u be a weak solution of the equation (-Δ)
m

u = f with Dirichlet boundary conditions in a smooth bounded domain Ω ⊂ ℝ
n
. In this paper, we obtain some estimates for the Green's function associated to this problem. Moreover, under appropriate conditions on p, we prove some weighted Sobolev a priori estimates for the solution u, where the weight is a power of the distance function. This result extends previous work by R. G. Durán and M. Sanmartino ([Indiana Univ. Math. J. 57 (2008), no. 7, 3463–3478] and [Anal. Theory Appl. 26 (2010), no. 4, 339–349]).
Existence of renormalized solutions for some strongly nonlinear elliptic equations in Orlicz spaces
Authors: Fqayeh Azeddine Aissaoui , Benkirane Abdelmoujib , El Moumni Mostafa , Youssfi Ahmed
Published: July 2015

We prove the existence of a renormalized solution for the Dirichlet problem associated to the nonlinear elliptic equations
div a(x,u,∇u) - div Φ(u) + g(x,u,∇u) = f in Ω,
in the general setting of Orlicz spaces, where
Φ ∈ 𝒞0(ℝ,ℝ
N
), the function g has a natural growth with respect to its third argument and satisfies the sign condition while the datum f belongs to
W
 -1
E

M¯(Ω). No Δ2-condition is needed for the considered N-functions.
Scale-up of an RF heated micro trickle bed reactor to a kg/day production scale
Authors: Fernández Javier , Chatterjee Sourav , Degirmenci Volkan , Rebrov Evgeny V.
Published: July 2015

The scale-up of a radiofrequency (RF) heated micro trickle bed reactor for hydrogenation of 2-methyl-3-butyne-2-ol (MBY) over a Pd/TiO
The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways
Authors: Kosyna Friederike K. , Nagel Marie , Kluxen Larissa , Kraushaar Kim , Depping Reinhard
Published: July 2015

Hypoxia-inducible transcription factors (HIFs) regulate hundreds of genes involved in cellular adaptation to reduced oxygen availability. HIFs consist of an O2-labile α-subunit (primarily HIF-1α and HIF-2α) and a constitutive HIF-1β subunit. In normoxia the HIF-α subunit is hydroxylated by members of a family of prolyl-4-hydroxylase domain (PHD) proteins, PHD1-3, resulting in recognition by von Hippel-Lindau protein, ubiquitination and proteasomal degradation. In contrast, reduced oxygen availability inhibits PHD activity resulting in HIF-1α stabilisation and nuclear accumulation. Nuclear import of HIF-1α mainly depends on classical nuclear localisation signals (NLS) and involves importin α/β heterodimers. Recently, a specific inhibitor of nuclear import has been identified that inhibits importin α/β-dependent import with no effects on a range of other nuclear transport pathways involving members of the importin protein family. In this study we evaluated the physiological activity of this importin α/β-inhibitor (Ivermectin) in the hypoxia response pathway. Treatment with Ivermectin decreases binding activity of HIF-1α to the importin α/β-heterodimer. Moreover, HIF-1α nuclear localisation, nuclear HIF-1α protein levels, HIF-target gene expression, as well as HIF-transcriptional activity are reduced upon Ivermectin treatment. For the first time, we demonstrate the effect of specific importin α/β-inhibition on the hypoxic response on the molecular level.
What can lipidomics tell us about the pathogenesis of Alzheimer disease?
Authors: Xiang Yanhui , Lam Sin Man , Shui Guanghou
Published: July 2015

Lipids serve many distinct functions in cellular homeostasis such as membrane organization, as a platform for membrane function and protein/protein or protein/lipid interaction, energy storage, as well as secondary messengers in signal transduction. Perturbations in lipid homeostasis may result in abnormal cellular function. Alzheimer’s disease (AD) is a neurodegenerative disorder in which the brain represents the primary site of pathology. While there is a plethora of previous work pertaining to AD pathogenesis, the precise mechanism of the disease is still not well-understood. Recent waves of technological advances in the realm of lipidomics have enabled scientists to look at AD pathogenesis from a previously unexplored perspective, and studies have revealed extensive lipid aberrations are implicated in the disease pathology. Herein, we review the critical lipids alternations, which affect amyloid plaque and neurofibrillary tangles formation and accumulation, as well as lipid aberrations related to neuronal and synaptic dysfunction in cells and animal models. We also summarize lipid abnormalities observed in the human cerebrospinal fluid (CSF), as well as other circulating fluids including plasma and serum in association with AD, which could serve as candidate biomarkers to diagnose and monitor the disease.
Quantifying and protecting location privacy
Authors: Shokri Reza
Published: July 2015

This thesis addresses the timely concern of protecting privacy in the
age of big data. We identify the two following problems as the
fundamental problems in computational privacy: (i) consistently
quantifying privacy in different systems and (ii) optimally protecting
privacy using obfuscation mechanisms. We cast the problem of
quantifying privacy as computing the estimation error in a statistical
(Bayesian) inference problem, where an adversary combines his
observation, background knowledge and side channel information to
estimate the user's sensitive information. This enables us to evaluate
privacy of users in different systems, and consistently compare the
effectiveness of different privacy protection mechanisms. We also
formulate the problem of optimizing user privacy while respecting data
utility as an interactive optimization problem (Bayesian Stackelberg
game), where both user and adversary want to maximize their own
objectives which are in conflict with each other. We apply our
methodologies to quantifying and protecting location privacy in
location-based services. We also provide an open-source tool, named
Location-Privacy and Mobility Meter (LPM), that enables researchers to
learn and analyze human mobility models as well as evaluating and
comparing different location-privacy preserving mechanisms.
Multidirectional, Multicomponent Electric Field Driven Assembly of Complex Colloidal Chains
Authors: Bharti Bhuvnesh , Velev Orlin D.
Published: July 2015

External fields (magnetic and electric) present a simple, robust and
efficient route to manipulate and assemble colloidal particles. We
report how biparticle dispersions can be assembled into well-defined
arrays of tunable morphology using external AC electric field. Binary
dispersions of strongly and weakly charged colloidal particles were
arranged into linear composite chains via dipole-dipole
attraction. The frequency of the applied electric field was the first
control parameter for reversibly tuning the biparticle attraction from
longitudinal assembly (in the direction of field) to the traverse one
(perpendicular to the field). We show that in addition to frequency,
spatial limitations play a key role in the assembly process and may
assist in the formation of short bidirectional chain-like clusters or
characteristic highly structured strings of colloidal triplets. Thus,
we control the long-range organization through a combination of
particle size ratio, concentration ratio and field frequency. The new
strategy to reconfigure the microstructures can find application in
better control of the field driven colloidal assembly processes and
may be extended to the formation of more complex and precisely
arranged particle networks.
Bipolarity and Sense in the Tractatus
Authors: Hanks Peter
Published: July 2015

Although the terms ‘poles’, ‘bipolar’, and ‘bipolarity’ do not appear in the Tractatus, it is widely held that Wittgenstein maintained his commitment to bipolarity in the Tractatus. As it is usually understood, the principle of bipolarity is that every proposition must be capable of being true and capable of being false, which rules out propositions that are necessarily true or necessarily false. Here I argue that Wittgenstein was committed to bipolarity in the Tractatus, but getting a clear view of this commitment requires a different understanding of bipolarity. Properly understood, bipolarity is the view that every proposition represents two possible states of affairs, one positive and the other negative. Of course, in the case of elementary propositions, the sense of a proposition is only the positive state of affairs. There is thus an asymmetry between what a proposition represents, its true-false poles, and what it says, its sense. In this paper I show how Wittgenstein accounted for this asymmetry in Notes on Logic and I consider two ways he might have accounted for it in the Tractatus.
The Battered Child Syndrome
Authors: Brown RH
Published: July 2015

Strange as it may seem, in this era of escalating intellectual enlightement, laws must be passed to protect innocent, harmless children from their parents and others who beat them into senselessness and even death. On 1 July 1965 such a law went into effect in Illinois, and Illinois became the 11th state to enact a child abuse statute [1]. Our law requires mandatory reporting of all definite or suspicious instances of child abuse to the Illinois Department of Children and Family Services. This legislation was drafted and its passage urged by a special committee appointed by the Illinois Commission on Children, of which I was a member. It was also endorsed by the Coroner of Cook County, whose office had examined many of the victims, and by many other interested persons who in their professional activities encountered battered children. All felt that the actual reporting and the concomitant publicity and education would serve as deterrents to this deplorable condition. Today, ten years later, the battered child has not been legislated out of existence, although all states now have similar reporting laws [2]. Both the incidence and the severity of these heinous acts continue to be alarming in our country as well as in many foreign countries [3–9]. Daily a large segment of our citizenry, the battered child, is being deprived of its right to life, liberty, and the pursuit of happiness. Physicians, attorneys, and other professionals must be in the forefront to diagnose the condition, treat the victims, take remedial action against the offenders, and attempt to formulate preventive measures.
Cadaveric Kidneys for Transplantation: Is There a Need for More?
Authors: Pliskin JS
Published: July 2015

Kidney transplantation is rapidly becoming the treatment of choice for end-stage renal disease [1,2]. Unfortunately, the paucity of donor kidneys has inhibited the more widespread application of this modality. A more than ample number of organs go to waste for various reasons.
Determination of Methaqualone in Urine by Metabolite Detection Via Gas Chromatography
Authors: Permisohn RC , Hilpert LR , Kazyak L
Published: July 2015

Pharmaceutical preparations of the sedative and hypnotic agent methaqualone have been widely prescribed and dispensed under a variety of trade names, including Quaalude®, Sopor®, and Parest®. Cases of methaqualone abuse and overdose have been well documented [1–3]. The ready availability and frequent abuse of methaqualone have led to the development of methods of analysis for methaqualone and its metabolites in biologic fluids. Nowak et al used thin-layer chromatography (TLC) to study the metabolism of methaqualone in laboratory animals [4]. Only a small fraction of the dose was detected as the unchanged drug in the urine of the rat, while the major portion of the dose was hydroxylated and excreted as glucuronide conjugates. Preuss et al isolated twelve metabolites from urine of human subjects who had ingested methaqualone [5]. By comparison of these twelve metabolites with a series of synthesized monohydroxy derivatives of methaqualone they were able to identify five monohydroxy metabolites of the drug.
Combined Effect of Methaqualone and Two Cannabinoids
Authors: Stone CJ , McCoy DJ , Forney RB
Published: July 2015

The purpose of this study was to determine the effect of pretreatment with cannabidiol (CBD) or Δ-9-tetrahydrocannabinol (THC) on methaqualone (MQ)-induced sleeping times. The duration of sleep was determined as the interval between the loss of righting reflex and its return. Male albino mice were injected intraperitoneally (i.p.) with either CBD or THC (10, 20, or 30 mg/kg) or vehicle. Thirty minutes later, an hypnotic dose of MQ (75 mg/kg) was administered. Animals receiving CBD or THC alone would not sleep. The sleeping time for MQ alone was approximately 30 minutes. In the presence of CBD or THC, MQ sleeping times increased significantly. The effect of THC was significantly greater than that of CBD.
The Spatial Distribution of Copper in Individual Human Hairs
Authors: Maes D , Pate BD
Published: July 2015

Studies of the trace element content of human hair are of interest from several points of view. Since trace elements enter hair from the environment; either directly or via the diet, their concentration in hair may represent an indicator of environmental quality [1–3]. Further, since hair samples are fairly durable, those secured in an historical or archeological context may provide environmental information from times past [4]. Erratum to this paper appears in 21(2).
Correlation of Lead and Cadmium in Human Urine
Authors: Lewis SC , Forney RB
Published: July 2015

Beginning in May 1973 the analysis of urine for the presence of cadmium has been performed in this laboratory on a routine basis. During the following months, the subjective impression emerged that when elevated urinary concentrations of lead were found, urinary cadmium concentrations were often elevated also. The present study was undertaken to evaluate the possible statistical relationship between the elevated concentrations of these two elements.
Some Aspects of Normal Behavior: Their Use in Understanding Problems Encountered by Document Examiners
Authors: McCarthy JF
Published: July 2015

It is unfortunate that in this country the need to separate the opinions of document examiners from those of graphologists has directed almost all handwriting research away from the areas of the behavioral sciences and toward the physical sciences. Because of this trend in research, little direct mention is normally made of the relationship of the behavioral sciences to document examination, although it is covertly mentioned in many papers. This attempt to pursue studies only in the pure sciences has placed a self-imposed limit of knowledge on document examination.
A Review of “Forensic Medicine”
Authors: Froede RC
Published: July 2015

The text of this concise volume attempts to cover all major aspects of forensic pathology and forensic medicine. The book is interesting, fairly timely, and easy to read. It is apparently designed to begin the education of the medical student, attorney, and novice criminal investigator in the rudiments of forensic medicine. In this, the book is quite successful, utilizing, in part, a format of question and answer. This can be particularly useful to a person who is developing a technique or method of investigation for the casual medicolegal case. This is the second edition of this little book that has found its way into my library, and I use it to give to a student to read over several days as a start in the field.