bluuebunny/crossref_metadata_2025 huggingface dataset:
The Interplay Between COVID-19 and Cardiovascular Disease
Authors: Shokoples Brandon , Ferreira Nathanne S. , Comeau Kevin
Published: August 2022

Introduction: The emergence of the global COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus, SARS-CoV-2, has created a substantial burden on healthcare systems worldwide. The systemic impacts of COVID-19 infection are severe and broad in their implications, and the cardiovascular system is no exception. Discussion: Patients with a history of cardiovascular disease are at an increased risk for hospitalization and mortality, and COVID-19 infection has now been demonstrated to initiate acute, but serious, episodes of cardiovascular events such as stroke. Considering the rapid spread of COVID-19 across the globe and the inability of healthcare systems to address and adequately respond to the pandemic, therein lies an increased need for understanding the interplay between COVID-19 infection and cardiovascular disease. SARS-CoV-2 relies on binding the angiotensin-converting enzyme-2 (ACE2) receptor to infect host cells, with ACE2 representing a critical regulator of blood pressure homeostasis and proper cardiovascular functioning. Conclusion: Identifying the exact role of ACE2 in COVID-19 infection will have major implications for understanding the disease; therefore, here we have reviewed ACE2’s involvement in the pathogenesis of COVID-19 infection and the resulting end-organ damage. In addition, we have summarized how COVID-19 affects cardiovascular physiology, and how COVID-19 infection can manifest in acute cardiovascular events. Finally, we examine why patients with cardiovascular disease are at an increased risk of succumbing to COVID-19 and what the long-term cardiovascular implications of COVID-19 infection could mean. Relevance: This paper discusses the cardiovascular consequences of the global COVID-19 pandemic.
Exercise-Induced Pulmonary Hypertension: How to Define, Diagnose, and Treat At-Risk Patients
Authors: Shokoples Brandon , Comeau Kevin
Published: August 2022

Introduction Pulmonary hypertension is a devastating disease with a rapid progression of symptoms leading to high patient mortality. It is characterized by high blood pressure in the pulmonary vasculature and poor pulmonary perfusion, resulting in patient fatigue, dyspnea, and syncope, especially upon physical exertion. A sub-clinical form of pulmonary hypertension also exists which is referred to as exercise induced pulmonary hypertension, where patients display normal resting hemodynamic properties but abnormal pulmonary responses to exercise.
Discussion Recent evidence suggests early intervention and treatment of pulmonary hypertension can improve patient outcomes. However, there is a lack of clinical evidence supporting effective treatments for exercise induced pulmonary hypertension (EIPH), arguably the earliest stage of pulmonary hypertension. This is due in part to the removal of EIPH from official guidelines such as the European Respiratory Society in 2008. EIPH was removed from clinical guidelines due to a lack of consensus on the definition and standardized testing procedures for diagnosing EIPH. Emerging evidence suggests that exercise testing following a standardized protocol of stress echocardiography or right heart catheterization of patients may allow for the classification of EIPH as a mean pulmonary artery pressure/cardiac output slope > 3 mmHg/L/min, and/or mean pulmonary artery pressure > 30 mmHg with a pulmonary vascular resistance > 3 Wood Units.
Conclusion Providing evidence for a consensus definition of EIPH, along with a validated, standardized testing procedure, will hopefully foster the progression of research on EIPH and further the development of treatments and improve patient outcomes for people with pulmonary hypertension.
Hochschild Cohomology of the Cohomology Algebra of Closed Orientable Three- Manifolds
Authors: Wang Qiu Shi
Published: August 2022

Let F be a field of characteristic other than 2. We show that the zeroth Hochschild cohomology vector space HH0(A) of a degree 3 graded commutative Frobenius F-algebra A = iAi, where we will always assume A0 = F, is isomorphic to the direct sum of the degree 0, 2 and 3 graded components and the kernel of a certain natural evaluation map ιμ : A1 Λ2(A1). In particular, this holds forA = H∗(M; F) the cohomology algebra of a closed orientable 3-manifoldM. In Theorem A of [1], Charette proves the vanishing of a certain discriminantΔassociated to a closed orientable 3-manifold L with vanishing cup product 3-form. It turns out that if we could show that HH2,−2(A) = 0for A = H∗(L;C), we would have found a more elementary proof of this part of Charette’s theorem. We show that for any β 3, the degree 3 graded commutative Frobenius algebra A with μA = 0and dim(A1) = β satisfiesHH2,−2(A) = 0. Thus Charette’s theorem is not simplified.
PRÁCTICAS SEGURAS PARA LA GESTIÓN DEL CUIDADO DEL PACIENTE COVID-19 EN EL HOSPITAL ANEXO VILLA ESSALUD FERREÑAFE – PERÚ, MARZO 2021
Authors: Bernal Corrales Fátima del Carmen , Gil Mendoza, Yosi  Muriel , Katerin  Isolina Katerin  Isolina , Julca Cruz Derlyn  Elina , La Madrid Satornicio Blanca Elena , Arbañil Nanfuñay Karen Cecilia
Published: August 2022

Objetivo: Evaluar el nivel de cumplimiento de las prácticas seguras para la gestión del cuidado enfermero del paciente COVID-19 en el Hospital Anexo Villa Essalud Ferreñafe – Perú, durante el mes de marzo 2021. Metodología: Estudio cuantitativo de diseño no experimental descriptivo de corte transversal, la muestra fueron 21 enfermeras del servicio de hospitalización medicina, empleándose la observación participante pasiva y el análisis documental de los registros de enfermería aplicando la lista de verificación: “cumplimiento de prácticas seguras para prevenir eventos adversos” de Essalud con una validez de KR-20 de 0,8. Resultados: El nivel de cumplimiento general de las prácticas en el Hospital Anexo Villa Essalud Ferreñafe se encuentra en un nivel aceptable en un 79%. En las dimensiones prevención de riesgo de caída, y prevención y reducción de las úlceras por presión el nivel de cumplimiento fue aceptable en el 52.4% y 61.0% respectivamente, evidenciándose un nivel óptimo en las dimensiones identificación segura de paciente (91.4%) y administración segura de medicamentos (85.7%). Conclusiones: Los profesionales de enfermería demostraron un nivel aceptable en el cumplimiento de las prácticas seguras, no obstante, deben mejorarse a fin de prevenir eventos adversos, debiendo fortalecer la cultura de seguridad del paciente.
Cyborgology and bioprinting: The biotechnological future of maxillofacial rehabilitation
Authors: Naveau Adrien , Smirani Rawen , Remy Murielle , Pomar Philippe , Destruhaut Florent
Published: August 2022

Maxillofacial prostheses now benefit from the growing advances in converging technologies, such as nanotechnologies, biotechnologies, informatics and cognitivism (NBIC). Instead of being laid and passive, prostheses can now ensure true neurophysiological interactions with their wearers through complex phenomena of hybridization and vicariance. These new devices get closer to â€œmaxillofacial amplification prosthesesâ€, by improving the world perception through restored sensory properties and new extra-sensory properties. These technological devices also benefit from the bioengineering revolution that will soon allow the bioprinting of graft prostheses with an intimate integration to the organic maxillofacial support. In this article, the authors would like to present some major advances in cyborgology and bio-printing in maxillofacial hybridization contexts. (Int J Maxillofac Prosthetics 2019;1:20-26)
A technique of speech aid adjustment with the assistance of nasalance values for non-nasal and nasal sounds
Authors: Liu Yinan , Hattori Mariko , Sumita Yuka I
Published: August 2022

Evaluation of speech function is essential to maxillofacial prosthetic treatment. Measurement of nasalance with a nasometer is practical and typically done to detect hypernasality in maxillofacial defect patients. This case report describes a nasalance test used in the evaluation and rehabilitation of a patient who needed a speech aid. A 70-year-old man sought help at our clinic because his old speech aid had broken. Although a new speech aid was fabricated, he continued to have difficulty speaking and breathing. A nasalance test using nasal and non-nasal test words revealed hyponasality. The patient was satisfied with the speech aid after its adjustment in accordance with the nasalance test results. Nasalance testing that considers not only hypernasality but hyponasality helped the maxillofacial prosthodontist in the successful rehabilitation of this maxillofacial defect patient. (Int J Maxillofac Prosthetics 2020;3:23-27)
Nutrition assessment of an elderly patient with recurrent advanced carcinoma of the maxilla: A case report
Authors: Murase Mai , Tani Hiroko , Ino Shuichi , Sumita Yuka I
Published: August 2022

Maxillectomy patients require a maxillofacial prosthesis for improving quality of life from the preoperative period to the stage of palliative care. This case report describes maxillofacial prosthetic treatment from the aspect of nutrition by following the condition of a 69-year-old woman who received surgery for a right-side carcinoma of the maxilla. After the initial treatment, metastatic disease was found, and her nutritional status worsened steadily. Although the prognosis may be poor, maxillofacial prosthodontic treatment should be given in order to maintain nutritional status and quality of life and to achieve optimal function for the patient as palliative care. (Int J Maxillofac Prosthetics 2020;3:28-31)
Peningkatan Bersihan Jalan Nafas Pada Anak Balita Penderita ISPA Dengan Terapi Uap Air Dan Minyak Kayu Putih Di Poliklinik AKPOL Semarang.
Authors: Susiami Susiami , Mubin Mohammad Fatkhul
Published: August 2022

Cakupan penderita ISPA melampaui target 13,4%, hasil yang diperoleh 18.749 penderita. Survei mortalitas yang dilakukan Subdit ISPA tahun 2015 menempatkan ISPA sebagai penyebab terbesar kematian bayi di Indonesia dengan persentase 22,30% dari seluruh kematian balita. Pasien ISPA ditandai dengan peningkatan sputum, salah satu upaya untuk mengeluarkan sputum adalah terapi uap. Studi ini bertujuan menerapkan  terapi uap air dan minyak kayu putih untuk meningkatkan bersihan jalan nafas pada pasien ISPA. Metode studi ini adalah study kasus dengan deskripsi dengan mengaplikasikan Terapi Uap Air dan Minyak Kayuputih dalam Meningkatkan Bersihan Jalan Nafas pada Pasien Anak Balita penderita ISPA di Poliklinik AKPOL Semarang dengan sampel 2 pasien balita. pengumpulan data dengan wawancara dengan keluarga, observasi dan pengukuran parameter kepatenan jalan nafas, tanda-tanda vital, intensitas batuk serta suara nafas Terdapat perbedaan sebelum dan sesudah dilakukan intervensi pemberian terapi menghirup uap air hangat di tambah minyak kayu putih terjadi peningkatan bersihan jalan nafas dengan ditandai penurunan rata-rata RR 5 x/menit, peningkatan rata-rata  saturasi 2%,  penurunan intensitas batuk dan menurunnya suara nafas tambahan. Intervensi mengirup uap air hangat dengan ditambahkan minyak kayu putih dapat meningkatkan bersihan jalan nafas pada pasien ISPA. Terapi menghirup uap air hangat dapat dijadikan terapi koplementar pada pasien ISPA dalam meningkatkan kepatenan jalan nafas.
Classification of Transmission Modes through a Narrow Slot in a Thick Conducting Screen
Authors: Kim Ki-Chai , Park Gyeong-Sik , Min Gyeong-Jun , Cho Young-Ki
Published: August 2022

This paper examines electromagnetic energy transmission through a narrow slot in a thick conducting plate when a plane wave is incident to the slot. The slot in the thick plate creates a waveguide structure. From the perspective of cutoff frequency, the transmission characteristics are classified into three modes. The transmission cavity resonance (TCR) mode in the range above the cutoff depends on the plate thickness, and peak transmission cross-sections (TCSs) appear periodically along the plate thickness, known as Fabry-Perot resonance. The near-cutoff resonance transmission (NCRT) mode depends on the slot length and plate thickness, and the maximum TCS appears only once as a slot length resonance (or transverse resonance). The peak TCS for the NCRT mode occurs with a thin plate thickness, which produces slot length resonance. The non-transmission cavity (NTC) mode is a non-transmission and non-resonance mode and is not propagated. All the maximum TCSs for the TCR and NCRT modes occur in parallel resonance. The analysis results show that the classification of the three transmission modes through the thick plate slot is effectively explained by the TCS and aperture impedance.
On Intuitionistic Fuzzy β Generalized α Normal Spaces
Authors: Al-Qubati Abdulgawad A. Q. , Al-Qahtani Hadba F.
Published: August 2022

In this paper a new concept of generalized intuitionistic fuzzy topological space called intuitionistic fuzzy β generalized α normal space is introduced. Several characterizations of intuitionistic fuzzy β generalized α normal space, intuitionistic fuzzy strongly β generalized α normal and intuitionistic fuzzy strongly β generalized α regular spaces are studied. Moreover, the related intuitionistic fuzzy functions with intuitionistic fuzzy β generalized α normal spaces are investigated.
Length-Weight Relation of the Angular Rough Shark, Oxynotus centrina (Linnaeus, 1758) in the Mediterranean Sea
Authors: KABASAKAL Hakan , ÖZBEK Elif Özgür
Published: August 2022

Oxynotus centrina is considered a rare or uncommon shark species throughout its distribution range. Because of this reason, it is one of the 46 uncommon elasmobranchs in the Mediterranean Sea, which requires filling the knowledge gaps, such as length-weight relations. Based on the analysis of 34 angular rough sharks, the length-weight relations (LWR) of males, females and combined sexes of O. centrina were described as W = 0.216L2.686, W = 0.134L3.041 and W=0.102L3.173, respectively. Total lengths (TL) of females and combined sexes were strongly correlated with total weights (TW); while TL of males was moderately correlated with TW. The b values of LWRs of females and combined sexes (3.041 and 3.173, respectively) were not significantly different from 3.0 (t-test, p>0.10) and indicated positive allometric growth for the examined TL and TW range of O. centrina in the Mediterranean Sea.
Extraction of Floor Session Area of Building Plots by Length Vector Additional Technique in Different Types of Zoning Building Organizations
Authors: TAŞKAYA Selim
Published: August 2022

Zoning plans are the design work required for the correct use of space in terms of urbanization. While creating zoning plans, zoning islands are created together with various planning methods. Reconstruction islands are also named as having legends such as residence, subject + commercial, commercial, social areas, religious facility areas called places of worship, green areas. The important part is how the construction permit is given to the parcels that will coincide within these islands. This process is the zoning diameter. Zoning diameters are the drawings made on the ground according to different methods. In our study on how to give the zoning diameter to different types of zoning islands, it was aimed to add the lengths of the parcels, which we call length vector addition, with each other to provide appropriate distances into them in a perpendicular or parallel manner. It was examined how the zoning island would be given a diameter in terms of length according to the precedent and the amount of height processed in the plan.
Detection of EEG Patterns for Induced Fear Emotion State via EMOTIV EEG Testbench
Authors: GÜMÜŞ Ahmet Ergun , UYULAN Çağlar , GULEKEN Zozan
Published: August 2022

In this study, International Affective Picture System (IAPS) were used to evoke fear and neutral stimuli using EMOTIV EPOC EEG recognition system (n=15). During the experiments, EEG data were recorded using the Test bench program. To synchronize the EEG records, IAPS pictures were reflected on the screen. A Python script was written in the Open Sesame program to provide a synchronized data flow in the Input/Output channels of the installed virtual serial port. The Event-Related Oscillations (ERO) responses and Event-Related Potentials (ERPs) were calculated. Statistically significant differences (p
Monitoring DNA Damage in Suez Pufferfish (Lagocephalus suezensis) from the Northeastern Mediterranean
Authors: TURAN Funda , ERGENLER Ayşegül , BARDAKÇI Fevzi
Published: August 2022

Industrial effluents, agricultural runoff, and municipal wastewaters contain unknown substances and complex mixtures that are released into the environment and can lead to contamination of surface and subsurface waters. Such activities have endangered the existence of ecosystems and their inhabitants. Changes in the genome caused by genotoxic agents led to mutations and pose a burden to the populations of fish species. In the present study, we have used the alkaline Comet assay to detect the genotoxicity in Suez pufferfish (Lagocephalus suezensis) sampled from two different gulfs (Iskenderun and Mersin Bay), Northeastern Mediterranean. At the end of the study, the damage frequency (%), arbitrary unit and genetic damage index (%) were evaluated in gill and liver cells of L. suezensis by comet assay. The DNA damage in the gill and liver cells of L. suezensis in the present study were observed with a higher level of DNA damage in gill cells compared to liver cells in both the Iskenderun and Mersin Bays. The highest level of DNA damage (55.01±1.02%), arbitrary unit (143.01±7.21) and genetic damage index (1.43±0.07 %) were found in gill cells of L. suezensis from Mersin Bay. Statistically significant differences were found between DNA damage, Arbitrary unit and genetic damage index values of the two locations (p < 0.001). In conclusion, this study indicates that comet assay gives sensitive results in monitoring the pollution, especially the pollution of the gulf, and thus it might be used as a standard method in regularly monitoring the pollution of the coastal ecosystem.
La salvación del no-pulido-no-pulcro: Hacia una est/ética salvífica
Authors: Troncoso-Gutiérrez Luciano Alfredo
Published: August 2022

En el presente estudio se busca recuperar la noción de Siervo de YHWH en clave de una estética salvífica, iluminada por la filosofía de Byung-Chul Han, Ignacio Ellacuría y otros autores. El fondo de ese escrito es mostrar el carácter estético de quienes han asumido, de manera comunitaria, la misma condición del Siervo de YHWH mencionado en el Deuteroisaías, que ha sido interpretado desde la fe cristiana en la figura de Jesús de Nazaret, además de poseer una connotación colectiva, rescatada por el pensamiento de Ellacuría. Desde esa interpretación se pretende abrir un camino en el pensar y el obrar cristiano, como una reflexión que pretende ubicar y valorar la dignidad de quienes han sido despojados de su humanidad y se han convertido en seres rechazables y discriminados, los cuales, no obstante, han abierto una grieta salvífica para las y los rechazados de la historia, sobre todo en América Latina.
¿Biopolítica o Zooantropolítica? Derrida lector de Foucault en La bestia y el soberano
Authors: Ramond Charles , Lugo Ariel
Published: August 2022

En el Seminario La Bestia y el Soberano, Derrida declara que “la zooantropopolítica, más que la bio-política”, es su “horizonte problemático”. Mostramos que la “biopolítica” concentra todas las paradojas de Foucault sobre la “novedad” en la historia y en el pensamiento. Foucault (como Agamben) está muy apegado a las “primeras veces”, que vienen a hacer ruptura y constituir nuevas “epistemes”. Pero, por otro lado, el esfuerzo constante de Foucault es “dar razón” de estas rupturas y restablecer una lógica completa en la sucesión de estas “epistemes”. Derrida no concede ni la novedad ni la necesidad histórica de la biopolítica. Se opone a esta concepción tradicional y logocéntrica de la filosofía, y del filósofo como vidente y dominador.
Pistas para una pedagogía teológica desde la Teología de la Liberación
Authors: Espinosa-Arce Juan Pablo
Published: August 2022

Los últimos acontecimientos sociopolíticos de nuestro país (estallido social, asamblea constituyente, pandemia) nos invitan a pensar cómo comunicar nuestra disciplina teológica en medio del entramado sociopolítico que nos contiene. Asumiendo que la Teología de la Liberación se articula desde lo dialogal, lo pastoral y el tono persuasivo de sus propuestas, el ensayo busca pensar qué características podrían sustentar una pedagogía teológica que, hundiendo sus raíces en la Teología de la Liberación, nos ayude a mirar, juzgar y actuar teológicamente en nuestra realidad social, política, eclesial o cultural. El sentido de lo “pedagógico” que buscamos trabajar no radica sólo en la presentación de métodos o procesos educativos determinados, sino que busca pensar contenidos y modos que, desde lo teológico, nos permitan proponer algunos criterios que tiendan a la formación de ciudadanos liberadores, de seres humanos comprometidos con el progreso y la transformación del desafiante mundo en que convivimos.
inscrição pelo discurso de uma criança norueguesa em processo de aquisição de português
Authors: Ramos Gesilda Marques da Silva
Published: August 2022

O presente trabalho tem como objetivo analisar um estudo de caso referente à inscrição de uma criança norueguesa pelo discurso no processo de aquisição de português como segunda língua. Reservamos a essa pesquisa a consideração da posição simultânea de pessoa subjetiva e pessoa não subjetiva sob a perspectiva de imprimir um olhar enunciativo do material pertencente ao sujeito enunciador, baseada na perspectiva enunciativa de Benveniste, já que favorece a interface enunciação e aquisição de linguagem. Essa abordagem considera o discurso como portador de uma mensagem e instrumento de ação, no qual o sujeito é capaz de, através do ato individual, conferir ao “tu”, a forma que marca o discurso e ao mesmo tempo, constituir-se como eu-tu, por intermédio de um diálogo com a sua própria voz, pelo fato de enunciar e desenvolver o processo de aquisição de linguagem ao mesmo tempo. Os resultados apontam, portanto, que o tu torna-se o eco do eu, favorecido pela mediação eu e tu como condição de apropriação da língua.
ensino-aprendizagem de outras línguas na escola pós BNCC
Authors: Silva Otávio de Oliveira
Published: August 2022

Este estudo traz à baila uma discussão que cinge à educação linguística em línguas adicionais alóctones, com enfoque no ensino de pomerano, problematizando a questão da democratização do ensino plurilíngue nas escolas públicas brasileiras. Objetivamos identificar possíveis óbices a partir da Lei nº 13.415 de 2017, que reformulou o ensino médio, e como consequência expurga das comunidades imigrantes (alóctones) o direito de escolha de outras línguas na escola, antes assegurado pela Lei de Diretrizes e Bases da Educação (LDB) 9394/1996. O estudo, constitui-se num trabalho de cunho descritivo e de abordagem qualitativa. Como base teórica apoiamo-nos nos estudos de Políticas Linguísticas de Calvet (2002,2004, 2007) e outros. Como resultados, apontamos os modelos de políticas linguísticas educacionais que resistem às diretrizes monolíngues e promovem o plurilinguismo escolar, tomando como exemplo as medidas de promoção do pomerano, gerenciadas pelas próprias comunidades (gestão in vivo) e pelos governos locais (in vitro).
(Auto) reflexão sobre uma aula remota de língua inglesa de orientação decolonial por meio da análise dialógica de memes
Authors: Lima Samuel de Carvalho
Published: August 2022

À luz da perspectiva dialógica da linguagem, este artigo apresenta uma (auto) reflexão sobre uma aula remota de língua inglesa por meio da análise de memes. Discute-se a experiência de promover o diálogo sobre a pandemia e a democratização do acesso à internet com jovens e adultos do ensino médio de uma escola pública federal. A análise de memes demonstra que a sua linguagem verbal responde criativamente a imagens de cenas de uma novela brasileira e de um filme hollywoodiano, denunciando a falta de democratização do acesso à internet por meio do humor e da ironia. Conclui-se que a leitura de memes, na aula de língua inglesa para jovens e adultos, pode promover a reflexão sobre os recursos expressivos que constituem esses textos e demandar dos estudantes respostas aos discursos sobre o acesso à internet no Brasil.
Avaliação de um curso on-line de estratégias de leitura em língua inglesa ministrado no início da pandemia
Authors: Santos Luana Viana dos , Pinto Paula Tavares
Published: August 2022

Dado o novo cenário social, gerado pela pandemia de Covid-19, no qual as práticas docentes realizam-se sob a condição de constante adaptação, o presente artigo busca analisar as atividades desenvolvidas no curso de Estratégias de Leitura em Língua Inglesa do nível básico ofertado como disciplina optativa a alunos de uma universidade multicampi, apresentar as médias finais dos estudantes para discutir seu nível de compreensão leitora e desempenho no curso, além de propor uma reflexão acerca do ensino on-line para graduandos durante o período pandêmico, em que se adotou o Ensino Remoto Emergencial (ERE) como medida alternativa de contenção de danos na educação. Com base em uma revisão bibliográfica e em uma pesquisa por meio de questionário, realizada com duzentos alunos, constata-se a necessidade de interação entre discentes e docentes durante o período de isolamento, bem como a importância do modelo de aulas síncronas para o bom aproveitamento da disciplina.
Author's idiostyle, linguistic and translation aspects
Authors: Aloshyna Maryna
Published: August 2022

The problem of individual author's Stylistics, its place in the system of already functioning verbal means and its role in realizing the unique pragmatic potential of a literary work and the author as a whole have become the basis for numerous studies in the field of linguostylistics, which indicates the relevance of this work. The purpose of the article is to study the linguistic and translation aspects of the author's idiostyle. Methods. The paper used scientific methods: generalization, systematization and classification of methodological sources and scientific approaches to the study of the concept of “idiostyle” in the system of linguistic analysis of literary texts in scientific works of Ukrainian and foreign researchers. Results. The semantic difference between the studied comparisons and metaphors revealed some semantic value of these tropes and their functions in establishing genre features of Stephen King's idiostyle. Conclusion. Structural differentiation of comparisons and metaphors allowed us to analyze the frequency of their use in the author's works. The most common type is a group of binomial nominative comparisons, while other groups have approximately the same number of examples. Among metaphors, the most widely used type is a simple metaphor with a single image. The analysis of the translation aspect of S. King's works shows that each author uses his own approaches in translating lexical and stylistic means aimed at implementing a strategy to create a certain atmosphere. But it should be noted that the most effective is the use of lexical and stylistic means close to the original, while omission, transliteration and often contextual substitution in translation reduce the effectiveness of creating certain emotions in the reader. The basis for further research is to determine approaches to the study of the author's idiostyle in the dramatic genre.
Teaching elements of kipchak language in north Azerbaijani groups (with emphasis on educational materials in the mother tongue)
Authors: Samedova Konul
Published: August 2022

The article discusses the morphological categories of the Azerbaijani language educational. The article also compares the use of case categories, and Northern dialects. In addition, the types of spelling and the number of cases of nouns in Oghuz and Kipchak languages and their integration with each other, as well as comparisons with other Turkic languages were made. The article discusses a single system of phonetic differences in the resolution of nouns. All names, all words, including infinitives are used in Turkish languages. According to their meanings and syntactic function, they are divided into two groups: grammatical and spatial. As an example, in most Turkish languages, six cases are accepted - noun, possessive, directional, influential, local and speech. However, Kazakh, Karachay-Balkar, Chuvash and others. In languages, there are two additional forms of conjugation and consonant. Therefore, the aim of this study was to teach elements of kipchak language in North Azerbaijani groups with emphasis on educational materials in the mother tongue.
Toward information equity among academic libraries
Authors: Currier Chad
Published: August 2022

For two decades, publishers and vendors have used e-book licenses to back academic libraries into a corner. These rightsholders and intermediaries lease rather than sell content, and they dictate what constitutes permitted downstream usages. Libraries have historically used interlibrary loans to fill gaps in collections, but publishers and vendors unilaterally claim that interlibrary loans of entire e-books infringe on their exclusive rights. As a result, libraries at small and mid-sized colleges and universities are constrained to providing patrons access only to e-books that fall within the limits of modest collections budgets. Grounded on the premise that e-book interlibrary loans are needed to advance and protect information equity in higher education, this presentation invites interdisciplinary discussions and collaboration with respect to the future of resource sharing in academic libraries.
Fact Checking After Truth
Authors: Haigh Maria , Haigh Thomas
Published: August 2022

The rise of “fake news” (misinformation presented in the format of news reports) and a claimed breakdown in a social consensus behind the reliability of experts and mainstream reporting as information sources (leading to a “post-truth” society) have raised hard choices for journalistic fact-checkers. Should they focus on nuanced evaluations of specific claims by politicians, or shift to debunking misinformation more generally? An analysis of fact-checking reports at the Washington Post around the 2016 and 2020 elections suggests little change in practice, in contrast to the 2014 Ukrainian initiative Stop Fake which attempted to debunk fake reporting.
Evaluasi Kerusakan Lapis Perkerasan Jalan dengan Metode Pavement Condition Index (PCI)
Authors: Rifqi Fauzi Dhiaulhaq  , Fauzan Muhammad
Published: August 2022

Jalan sangat dibutuhkan karena segala bentuk pergerakan terutama pergerakan transportasi darat memakai sistem jaringan transportasi yang ada. Pertumbuhan baik dari sisi ekonomi, perdagangan, serta sektor lain akan berkembang lebih dengan adanya keberadaan jalan. Penyebab kondisi jalan di Indonesia masih buruk yaitu karena pembangunan jalan yang tidak diimbangi dengan pemeliharaan yang baik. Berdasarkan data Badan Pusat Statistik Provinsi Jawa Barat tahun 2018 diketahui bahwa daerah Bogor memiliki jalan dengan kondisi rusak hingga rusak berat. Jalan Alternatif IPB merupakan jalur alternatif untuk menuju Kampus Institut Pertanian Bogor (IPB). Intensitas kendaraan yang cukup padat menyebabkan banyaknya kerusakan. Kerusakan ringan hingga berat terjadi di beberapa ruas jalan. Penelitian bertujuan untuk mengidentifikasi jenis kerusakan jalan, melakukan penilaian berdasarkan metode PCI, serta memberikan solusi perbaikan untuk setiap perkerasan jalan yang rusak pada Jalan Alternatif IPB. Penelitian dilakukan pada Jalan Alternatif IPB sepanjang 500 m dengan lebar perkerasan 4 m yang dibagi menjadi 10 section. Terdapat 6 jenis kerusakan, seperti kerusakan lubang, ambles, retak memanjang, tambalan, bahu turun, dan retak tepi. Nilai akhir PCI pada lokasi penelitian sebesar 69,4 sehingga masuk dalam kategori sedang. Solusi perbaikan untuk setiap kerusakan tidaklah sama. Penambalan permukaan dan penambalan seluruh kedalaman dapat digunakan untuk perbaikan semua jenis kerusakan, kecuali bahu turun. Bahu turun harus diperbaiki dengan perataan kembali serta bahu diurug. Micro surfacing digunakan untuk perbaikan ambles. Penutup retak digunakan untuk retak memanjang dan retak tepi.
Research question approach in the study of neonatal sepsis
Authors: Magda Olivia Pérez-Vásquez , José Locia-Espinoza , Luz Irene Pascual-Mathey
Published: August 2022

Neonatal sepsis is a systemic infection that causes high morbidity and mortality rates in newborns during the first month of life. Although there is abundant literature on the subject, it remains a fundamental public health problem due to its high prevalence in underdeveloped countries. This article aims to highlight the importance of the approach in investigating neonatal sepsis using causality research questions, which generate knowledge to promote better care and reduce the complications associated with neonatal sepsis in newborns.
Melanoleuca tristis (Basidiomycota, Agaricales), a new record from western Mediterranean region of Türkiye
Authors: KAYGUSUZ Oğuzhan , ŞENGÜL Meryem Şenay
Published: August 2022

A rare species, Melanoleuca tristis is reported for the first time from Türkiye on sandy soil under Pinus nigra subsp. pallasiana forest, a characteristic habitat of the Mediterranean region. Phylogenetic analysis based on a dataset of the nuclear ribosomal DNA (rDNA) internal transcribed spacer (ITS) sequences is performed to support the identification and to compare with similar taxa. The description, a color photograph of the basidiomata and microscopic drawings are given.
Analisis Penerapan Penurunan Nilai Aset Tetap Berdasarkan PSAK 48 pada Rumah Sakit Muhammadiyah Babat-Lamongan
Authors: Nuraini Fitri , Niswah Alda Ainun , Rono Soedjono
Published: August 2022

ABSTRACTThe purpose of this study was to determine the uses of accounting of value fixed assets impairment in the surgery room of the Muhammadiyah Hospital of Babat, lamongan based on PSAK No.48. Medical equipment that used in the surgery room of the Muhammadiyah hospital of Babat, Lamongan is the object of this study , and the method of the used in this study is descriptive qualitative with a case study approach. The technique that used is documentation. The result of this study shows that Muhammadiyah hospital of Babat, Lamongan has not decreased of the value assets surgery room medical equipment based on PSAK No.48. The suggestion for Muhammadiyah hospital of Babat, Lamongan are expected to decrease the values of assets in order to make Muhammadiyah hospital of Babat, Lamongan knows that some of medical equipments in surgery room have decreased in value.ABSTRAK            Tujuan penelitian ini adalah untuk mengetahui penerapan akuntansi penurunan nilai aset tetap Ruang Operasi Rumah Sakit Muhammadiyah Babat berdasarkan PSAK NO. 48. Alat medis ruang operasi RS Muhammadiyah menjadi objek pada penelitian ini dan metode yang digunakan dalam penelitian ini adalah penelitian deskriptif kualitatif dengan pendekatan studi kasus. Teknik yang digunakan adalah dokumentasi. Hasil penelitian menunjukkan bahwa, RS Muhammadiyah Babat belum melakukan penurunan nilai aset alat medis ruang operasi berdasarkan PSAK No. 48. Saran untuk RS Muhammadiyah Babat diharapkan untuk melakukan penurunan nilai aset yang bertujuan agar RS Muhammadiyah Babat mengetahui bahwa beberapa alat medis ruang operasi mengalami penurunan nilai.
Research on the main methods and schemes of encryption with search capability
Authors: Yesin V.I. , Vilihura V.V.
Published: August 2022

The growing popularity of data outsourcing to third-party cloud servers causes their owners to have serious concerns about their security due to possible data leakage. A well-known measure to solve this problem and ensure the confidentiality of data is to encrypt it. However, the use of traditional encryption techniques is faced with the problem of how to allow untrusted cloud servers to perform search operations, while the actual data transmitted must remain confidential. Searchable encryption is a powerful tool, a class of cryptographic techniques that attempts to solve this problem. Searchable encryption acts as a data management technique that allows data owners to store and manage their data on a third-party, untrusted cloud server, and allows the data user to delegate search functions to the cloud server to retrieve that data. Currently, there are a number of approaches to solving this problem, although there is still no dominant solution. Therefore, the paper presents an overview of current secure search solutions. The main searchable encryption techniques are considered, which allow you to perform search operations on encrypted data without disclosing any information about what is being searched. The strengths and weaknesses of the analyzed methods are highlighted. Models and architectures of existing secure search engines are analyzed, taking into account the peculiarities of their operation scenarios. The problem of confidentiality in searchable encryption schemes is discussed. A comparative analysis of the performance of several searchable symmetric encryption schemes is given. Various gaps in the area under consideration are identified, with indication of open research problems.
Разработка методики получения ассоциатов бромелина с микро- и наночастицами хитозана
Authors: Редько Юлия Александровна , Ольшанникова Светлана Сергеевна , Холявка Марина Геннадьевна , Лавлинская Мария Сергеевна , Сорокин Андрей Викторович , Артюхов Валерий Григорьевич
Published: August 2022

Синтезированы микро- и наночастицы среднемолекулярного и высокомолекулярного хитозанов без и с добавлением аскорбиновой кислоты. Получены ассоциаты бромелина с микро- и наночастицами хитозана. Ассоциаты бромелина с микро- и наночастицами хитозана обладают более высокой стабильностью по сравнению с растворимым ферментом. Снижение протеолитической активности препарата наблюдалось в течение 7 суток эксперимента. Каталитическая способность ассоциатов бромелина с частицами, синтезированными в присутствии аскорбиновой кислоты, была выше, чем с частицами обоих типов хитозанов, синтезированными при ее отсутствии: для микро- и наночастиц среднемолекулярного хитозана эта разница составила 17 и 21 %, соответственно, для микро- и наночастиц высокомолекулярного хитозана — 23 и 26 %, соответственно.
Исследование зависимости «структура — анальгетическая активность» с использованием экспериментальной модели у мышей и молекулярного докинга по циклооксигеназам 1 и 2 в ряду амидов и гидразидов N-замещенных 3,5-дибром(H)антраниловых кислот
Authors: Андрюков Константин Вячеславович , Коркодинова Любовь Михайловна
Published: August 2022

Описан молекулярный докинг 24 амидов и гидразидов N-замещенных 3,5-дибром(H)антраниловых кислот (I – XXIV) с ферментами циклооксигеназа-1 и циклооксигеназа-2 (ЦОГ1 и ЦОГ2). Исследована зависимость экспериментальных значений анальгетической активности (AAэксп.) от скоринговых функций (BeЦОГ1, ImeЦОГ1, KiЦОГ1, BeЦОГ2, ImeЦОГ2, KiЦОГ2) и констант липофильности (logPрасч.) и ионизации (pKa расч., pKb расч.). Выбрано оптимальное уравнение регрессии № 2 для поиска биологически активных соединений с AA: AAрасч. = –9,058 + 5,315pKa расч. + 7,157ImeЦОГ1 – 7,382BeЦОГ1 – 0,003KiЦОГ1 – 0,186BeЦОГ2 (R = 0,80; F = 6,49; S = 4,91; Q2LOO = 0,65). Выполнена проверка уравнения регрессии № 2 прогнозированием AA (AAрасч.) на экспериментальных данных (AAэксп.), полученных на мышах по методике «Горячая пластинка», независимой выборки из 6 соединений (XXV – XXX), в результате получено высокое значение коэффициента корреляции (R) AAрасч. с AAэксп. (R = 0,713).
Фармакологические вещества, проявляющие противовирусную активность в отношении коронавируса SARS-CoV-2
Authors: Еникеева Д. А. , Бондарчук Наталия Геннадьевна
Published: August 2022

Представлены данные о процессе репродукции SARS-CoV-2 и рассмотрены возможные мишени для фармакологических веществ. Изложены сведения об ингибиторах РНК-полимеразы, главной протеазы и ингибиторах прикрепления и пенетрации коронавируса. Приведены данные о механизме действия противовирусных препаратов, их безопасности и эффективности при COVID-19.
Оценка влияния индивидуальных характеристик добровольцев и режимов введения на фармакокинетику янтарной кислоты в составе разных лекарственных препаратов
Authors: Василюк Василий Богданович , Верведа Алексей Борисович , Коваленко А. Л. , Фарапонова Мария Валерьевна , Сыраева Гульнара Ислямовна
Published: August 2022

Проведен сравнительный анализ фармакокинетических параметров янтарной кислоты после внутривенного введения препаратов «Унифузол, раствор для инфузий 1,4 %», «Реамберин, раствор для инфузий 1,5 %», «Ремаксол раствор для инфузий», «Цитофлавин, раствор для внутривенного введения» (ООО «НТФФ «ПОЛИСАН», г. Санкт-Петербург) по результатам серии клинических исследований, осуществленных в 2017 – 2022 гг. Установлено, что двухкамерная модель является оптимальной для определения параметров фармакокинетики янтарной кислоты, получены значимые различия между исследуемыми препаратами по фармакокинетическим параметрам (Cmax, Tmax, AUC0-∞, MRT), что связано с особенностями содержания активных компонентов, дозой и режимом введения. При этом антропометрические и гендерно-возрастные особенности добровольцев не оказывали значимого влияния на большинство фармакокинетических параметров янтарной кислоты.
Влияние афобазола и флуоксетина на депрессивноподобное поведение мышей BALB/C при моделировании расстройства аутистического спектра
Authors: Капица Инга Геннадиевна , Алымов Александр Александрович , Савинкова Елена Владимировна , Воронина Татьяна Александровна , Середенин Сергей Борисович
Published: August 2022

Изучено влияние афобазола в сравнении с флуоксетином на депрессивноподобное поведение самцов и самок мышей линии BALB/c на экспериментальной модели расстройств аутистического спектра, вызванного однократным постнатальным введением вальпроата натрия в дозе 400 мг/кг. Установлено, что афобазол (10 мг/кг перорально с 15 по 52 дни постнатального развития) значимо снижал продолжительность иммобильности у самок мышей BALB/c в тесте «Подвешивание за хвост», не изменяя показатели нарушенного поведения у самцов с расстройствами аутистического спектра. Сходные эффекты установлены для флуоксетина в дозе 10 мг/кг (перорально с 15 по 52 дни постнатального развития).
Влияние нового производного оксима 4-бензоилпиридина — ГИЖ-298 и вальпроевой кислоты на тревожное и депрессивноподобное состояния, когнитивные функции в эксперименте
Authors: Гайдуков Игорь Олегович , Литвинова Светлана Александровна , Воронина Татьяна Александровна , Гладышева Наталья Анатольевна , Волкова Анна Валерьевна
Published: August 2022

В настоящем исследовании в экспериментах на самцах белых беспородных мышей установлено, что новое производное оксима 4-бензоилпиридина — соединение ГИЖ-298, наряду с выявленными ранее выраженными противосудоржными эффектами, оказывает позитивное влияние на эмоциональное поведение, в частности, на тревогу, которая является одним из основных коморбидных расстройств у больных эпилепсией. Показано, что соединение ГИЖ-298 (40 мг/кг), вальпроевая кислота (150 мг/кг) и мексидол (150 мг/кг) при однократном и курсовом (7 дней) введении (внутрибрюшинно) обладают выраженным анксиолитическим действием в тесте «Приподнятый крестообразный лабиринт», достоверно увеличивая время нахождения животных в открытых рукавах лабиринта и число заходов в них. При этом анксиолитический эффект вальпроевой кислоты, но не ГИЖ-298 и мексидола, сопровождается седативным действием. Показано, что ГИЖ-298 не нарушает когнитивные функции в тесте «Оценка пространственной рабочей памяти в Y-образном лабиринте» и не оказывает антидепрессивного эффекта в тестах «Вынужденное плавание по Порсолту» и «Подвешивание за хвост». Уникальное сочетание у соединения ГИЖ-298 противосудорожных и анксиолитических свойств определяется его влиянием на сенсомоторную кору и гипоталамус, которые участвуют как в проявлении судорожной активности, так и в регуляции эмоционального поведения, в том числе, тревожности.
Avrupa İnsan Hakları Sözleşmesi’nde Siyasi Parti Özgürlüğü: AB Uygulaması ve Türkiye Örneği
Authors: KARA Adem
Published: August 2022

Bu çalışmada, Avrupa İnsan Hakları Sözleşmesi’nde (AİHS) siyasi parti özgürlüğünün AB ülke uygulamaları ve Türkiye örneği bakımından araştırılması amaçlanmıştır. Çalışma kapsamında AİHS hükümleri, Avrupa İnsan Hakları Mahkemesi (AİHM) içtihadı, Venedik Kriterleri, Avrupa Konseyi Parlamenterler Meclisi tarafından getirilen standartlar, bazı AB ülkelerindeki uygulamalar ve Türkiye pratiği incelenmiştir. Bu kapsamda iç hukukta siyasi parti özgürlüğüne ilişkin mevzuat ve içtihadın AİHS hükümlerine ve AİHM içtihadına uygunluk yönünden birtakım sorunlar barındırdığı tespiti yapılmıştır. Çalışmada anayasada ve mevzuatta yer alan hükümlerin AİHS hükümleri ve AİHM içtihadı paralelinde yeniden gözden geçirilerek değiştirilmesi gerektiği belirtilmiştir. Ayrıca siyasi parti kapatma davalarında Anayasa Mahkemesinin mer’i mevzuatı AİHM içtihadı ile uyumlu bir yaklaşımla yorumlayarak karar vermesi gerektiği değerlendirmesi yapılmıştır.
PENINGKATAN KAPASITAS PERANGKAT DESA BERBASIS SMART HUMAN RESOURCE DI DUSUN GUNTUNG KABUPATEN BATUBARA
Authors: Ramdhan William , Rahayu Elly , Santoso Santoso
Published: August 2022

Implementasi teknologi di era society 5.0 menghadirkan konsekuensi besar bagi setiap organisasi termasuk organisasi di sektor pemerintahan. dimana aparatur birokrasi pemerintahan memerlukan pengelolaan sumber daya manusia (SDM) yang optimal guna mendongkrak kredibilitas organisasi dengan meningkatkan efisiensi di bidang informasi, komunikasi, dan teknologi (TIK), guna mewujudkan good government dengan tujuan mempermudah pelaksanaan tugas-tugas di masa depan. Perubahan administrasi yang masih dilakukan secara manual menjadi terkomputerisasi yang mana merupakan implementasi dari sebuah konsep smart human resource information system (Smart-HRM). Sistem yang ternintegrasi pada Smart-HRM memberikan kemudahan bagi manajemen atau pengambil keputsan dalam mengelola informasi secara cepat dan efisien. Kantor Dusun Guntung masih melakukan seluruh proses administrasi secara konvensional sehingga  permasalahan yang terjadi penyimpanan dokumen membutuhkan banyak ruang dikantor dan dalam hal pencarian akan semakin sulit apabila dokumen tidak disimpan dengan teratur.  Jika hal ini dibiarkan terus menerus dengan budaya organisasi yang masih tetap menggunakan sistem manual, dikhawatirkan akan memperlambat dan mempengaruhi kinerja administrasi yang mengakibatkan tidak tercapainya tujuan organisasi. Sistem E-Office merupakan solusi untuk mengatur pola pekerjaan yang sudah atau akan dilakukan oleh pegawai, menyimpan, dan mengontrol konten-konten yang ada didalam suatu organisasi secara elektronik. Hasilnya penerapan E-Office di Kantor Dusun Guntung berbasis Web memudahkan pegawai untuk melakukan pengelolaan dokumen yang diperlukan.
PELATIHAN PELVIC FLOOR MUSCULE EXERCISE (PFME) PADA LANSIA DALAM MENINGKATKAN FUNGSI DEFEKASI
Authors: Windahandayani Veroneka Yosefpa , Pranata Lilik , Ajul Keristina , Fari Aniska Indah
Published: August 2022

Elderly is part of the life process that cannot be avoided and will be experienced by every individual. The aging process can cause various problems both physically, biologically, socio-economically and mentally. One of the biological disorders that occur in the elderly is defecation disorders. Defecation is the process of removing waste products from the body. Defecation removes the remains of digestion or also substances that do not undergo the digestive process, these substances are in the form of feces that are excreted through the anus. One of the methods used to improve the function of defecation and micturition is Pelvic Floor Muscule Exercises (PFME). The purpose of community service is to train the elderly to do PFME in order to improve defecation function. Training activities for 6 consecutive days, with 15 elderly living in elderly social institutions. The results of the activity show that the activity can increase defecation even though it is not significant. These results state that Pelvic Floor Muscule Exercises (PFME) activities need to be carried out routinely at social institutions for the elderly to help reduce disorders in elderly defecation.