bluuebunny/crossref_metadata_2025 huggingface dataset:
Study results of siberian moth (Dendrolimus sibiricus Tschetw.) outbreak foci in Vasyugan forestry of Tomsk region
Authors:   FBU «Russian Forest Protection Center», Denisova N.B. , Sobolev A.A. ,   BMSTU (Mytishchi branch), Shipinskaya U.S. ,   FBU «Russian Forest Protection Center»; BMSTU (Mytishchi branch)
Published: November 2020

This article presents the results of the inventory of outbreak foci of D. sibiricus in the Vasyugan forestry, Tomsk region. The purpose of the article was reflecting the state of the pest population and assessing a threat of defoliation of forests. Pests were measured by caterpillars using the method of knocking on model trees. According to the results, 29 isolated foci were identified, including 9 foci requiring actions to target pests. The threat of defoliation of forest areas in these foci was 76,3 %. The article gave us the examples of calculation of population characteristics determination in one foci using the conversion factors based (Ilyinsky, 1965). Defoliation, weather conditions in 2018 and development of entomophage have had a negative impact on the population. Also there is a risk of the pest spreading beyond its natural habitats. Möykkynen and Pukkala in the article «Modelling of the spread of a potential invasive pest, the Siberian moth in Europe» makes a forecast of D. sibiricus resettlement in Europe, Belarus and the Baltic States will be most at risk of settlement. Also, of particular concern are the prerequisites for the occurrence of pest outbreaks in the European part of Russia, therefore, in order to prevent insect resettlement beyond the boundaries of their range, it is necessary to conduct forest-pathological monitoring of populations on the territory of existing outbreaks and in places of primary reservation.
Connection between Saving, Investment and Economic Growth of India
Authors: Saxena Swami Prasad , Fouzdar Akanksha Singh
Published: November 2020

This paper scrutinizes the relationship between gross domestic saving, gross capital formation and economic growth in India during a period from 1992 to 2018. The results of cointegration analysis reveal that there is a long-run relationship between selected variables; however, the observations from the results of the Granger causality test indicate a positive relationship between saving, investment and economic growth in India. The findings explicate that saving and investment directed growth is coming from the private sector.
Ensino de Química e Letramento Científico
Authors: Vaz Wesley Fernandes , Bispo Nayara Regina
Published: November 2020

O livro didático é um importante recurso para embasamento e aporte teórico do professor. Nesse sentido, este artigo, recorte de uma pesquisa de mestrado, discute a abordagem de letramento científico nos conteúdos de termoquímica nos livros didáticos de Química do Programa Nacional do Livro Didático (PNLD), de 2008 a 2018. Esta pesquisa teve como premissa uma abordagem qualitativa. Para a coleta de dados, foram utilizada a análise bibliográfica; o tratamento dos dados através da análise textual discursiva. Foi possível inferir que no letramento foi examinada a predominância de textos escritos pelos agentes de produção do livro didático e poucos textos de fontes e gêneros textuais variados. Dessa forma, apesar dos avanços alguns livros de Química ao longo do PNLD, ainda não contempla a formação para a cidadania.
BIOACCUMULATION RISK ASSESSMENT OF AFLATOXIN B1, OCHRA-TOXIN AND FUMONISIN B1 IN TENEBRIO MOLITOR LARVAE
Authors: MANCINI ARIANNA , DREASSI ELENA , BOTTA MAURIZIO , TARCHI FRANCA , FRANCARDI VALERIA
Published: November 2020

The industrial farming of edible insects for food and feed generally employs cultivated plants and derivatives as rearing diets. These feed substrates may contain toxins produced by different species of fungi which cause ad-verse health effects to consumers. Frequently found in cereals and cereal products, mycotoxins aflatoxins, ochra-toxins and fumonisins are harmful to human and animal health. In this study the uptake of aflatoxin B1 (AFB1), ochratoxin A (OTA) and fumonisin B1 (FB1) and their elimination rates were investigated in T. molitor larvae fed on cereal-based diets contaminated with two concentration levels for each mycotoxin. New analytical methods for extraction and quantification of AFB1, OTA and FB1 residues in larvae were developed andvalidated.It has been demonstrated that T. molitor larvae did not accumulate in detectable or dangerous concentrations the three tested mycotoxins at the two tested concentration levels and that a fasting period of 24 hours ensured a suffi-cient elimination rate of AFB1, OTA and FB1 residues. These results represent a preliminary investigation to define an appropriate quality control procedure to assess the safe use of T. molitor for food and feed purposes.
Robotización/automatización y despido objetivo por causas técnicas (Art. 52 c ET)
Authors: Jurado Segovia Ángel
Published: November 2020

Una notable repercusión mediática ha tenido la sentencia de un Juzgado de loSocial de las Palmas que, asumiendo como premisa que la robotización comportaráuna fuerte destrucción del empleo, declaró improcedente un despido -ex art.52 c) ET- que había sido acometido por la empresa invocando la implantaciónde un nuevo software que permite automatizar las funciones de la trabajadoradespedida. La sentencia se decanta por una interpretación claramente restrictiva,que circunscribe la procedencia de estos despidos a las empresas que atraviesendificultades. En el presente trabajo, se reseña, en primer lugar, críticamente dichasentencia, subrayando que la lectura realizada no se ajusta a la letra y espíritu dela norma vigente; y, en segundo lugar, se abordan diversas cuestiones en tornoa lo que, a juicio del autor, constituye el esquema hermenéutico apropiado enpunto al control judicial de estos despidos por “causas técnicas”.
Los cambios en la gestión del régimen de clases pasivas: ¿un ataque a las singularidades de los regímenes especiales de funcionarios?
Authors: Esteve-Segarra Amparo
Published: November 2020

El objetivo de este trabajo es analizar los cambios en la gestión del régimen de clases pasivas aprobados durante el 2020 dentro de la legislación de urgencia suscrita durante el estado de alarma. El traspaso de la gestión al Instituto Nacional de Seguridad Social plantea tres cuestiones: primero, si el traspaso es técnicamente adecuado; segundo, por qué se ha efectuado en un real decreto ley de medidas para paliar los efectos económicos del COVID-19 una medida que afecta a la gestión de las pensiones de funcionarios, y, tercero, qué puede suponer este cambio de gestión para las especialidades contenidas en este régimen especial.
Panorama de la protección de los derechos de las trabajadoras en España y México
Authors: Carrillo Salgado Augusto Fernando
Published: November 2020

La finalidad de este documento consiste en describir los aspectos básicos a través de los cuales son protegidos los derechos de las trabajadoras en los sis­temas normativos español y mexicano. En otras palabras, introducir al lector a la forma en que son tuteladas las prerrogativas de las trabajadoras en ambos países. El estudio de los elementos protectores de los derechos de las trabajado­ras en los sistemas normativos referidos se efectúa desde tres ángulos: externo (derecho internacional), interno (derecho nacional) y judicial (actividad de sus tribunales constitucionales). Los métodos empleados en la elaboración de este documento son el deductivo, derecho comparado, histórico y analítico.
El ingreso mínimo vital: la renta garantizada de un Estado del bienestar incompleto
Authors: Ochando Claramunt Carlos , Albert Moreno Juan Francisco
Published: November 2020

1
Situación de necesidad económica y Seguridad Social: el Ingreso Mínimo Vital como eje de la tutela
Authors: Barcelón Cobedo Susana
Published: November 2020

2
THE EFFECT OF HEADS’ LEADERSHIP AND NURSES’ JOB MOTIVATION ON NURSING PERFORMANCE IN THE HOSPITAL INPATIENT ROOM
Authors: Hartono Budi , Hidayati Alfi , Kurniati Tri , Basir Nur'Aina
Published: November 2020

Background: The fluctuated patient satisfaction level shows the need to improvenursing performance. Several factors that can improve nursing performance includeleadership, job motivation, management and environment. Leadership and job motivationbecome fundamental aspectsin improving employee performance. Aim: This study analyzedtherole of manager’s leadership and nurses’job motivation on nursing performance in the inpatient room ofthe Indonesian Red Cross Hospital Bogor.Methods: This study sampled a total of 150 nurses in the inpatient roomof the Indonesian Red Cross Hospital Bogorusing the incidental random sampling technique. This study employed a path analysis with three variables, such as manager’s leadership and job motivation as exogenous variables and nursing performance as an endogenous variable.Results: Leadership of the head of the inpatient room couldincrease job motivation and nursing performance.Conclusion: Manager’s leadership and job motivation could affect the level of nurses’ performancepartially and simultaneously. The Indonesian Red Cross Hospital Bogor could provide regular training to every head of the room to enhance their leadership and nurses’ job motivation. Keywords: leadership, job motivation, nurses’ work performance.
Risk Factor Mild Mental Retardation in Extraordinary School at Surabaya
Authors: Imaduddin Muhammad Helmi , Febriyana Nining , Setiawati Yunias , Irwanto Irwanto
Published: November 2020

Background:  Children with mild mental retardation tend to have late language skills so that it affects aspects of speech and independence and can persist into adulthood. Knowing the risk factor of mental retardation is important because disability in children can be prevented by knowing the cause. Objective: This study aims to analyze risk factors for students with mild mental retardation in special schools in Surabaya in the academic year 2019-2020. Methods: This study was an observational analytic study with a case-control approach that took primary data in the form of a questionnaire on parents. Then the data is analyzed through univariate to display the characteristics of respondents and descriptive research variables and bivariate analysis with a chi-square test to determine the effect of risk factors on mental retardation. Results: In this study, there was a total of 100 samples after being excluded from 192 samples. Factors obtained by the length of neonatal stay in the hospital (p=0.010, OR=0.318, 95%CI=0.131-0.775), baby cries immediately at birth (p=0,000, OR=0.052, 95%CI=0,007-0,417), antenatal care (p=0.014, OR=0.107, 95%,CI=0.013-0.889), LBW (p=0.002, OR=0.820, 95%CI=0,72000,934), prematurity (p=0,007, OR=0,148, 95%CI=0,031-0,706), family income (p=0,000, OR=0.077, 95%CI=0.028-0.207), father's education (p=0.001, OR=5.310, 95%CI =1,913 14,745) affect mild mental retardation. Conclusion: Factors that influence mild mental retardation consist of perinatal factors (baby crying at birth) and environmental factors (family income and father's education).
Frotteuristic Disorders
Authors: Putri Ayu Nuzulia , Soetjipto Soetjipto
Published: November 2020

Frotteuristic disorders is a rare paraphilia among other paraphilia. Frotteuristic are usually acquired with other paraphilia such as exhibitionism. Frotteuristic disorders is rubbing the genital area on other people to cause orgasm. This action often occurs in public area such as subways, elevators or shopping centers where victims are unaware. Some studies have difficulty getting data on frotteuristic disorders because this sexual harassment rarely reported to the police because there are no witnesses or evidence. This literature reviews aims to determine the comprehensive treatment for frotteuristic disorders.
Design, Synthesis and In Vitro Biological Evaluation Of
N-(2-Aminophenyl)-3-Quinolin-4-yl -Prop-2-enamide
Derivatives As Novel Colon Anticancer Agents
Authors: Gagare Sunita S. , Choudhari Vishnu P. , Jain Ashish
Published: November 2020

Acetylation and deacetylation of histone proteins is regulated through two
enzymes; acetylation is mediated through histone acetyl transferase (HAT) whereas
deacetylation is mediated through histone deacetylase (HDAC). Histone deacetylase removes
acetyl group of lysine residue on histone proteinthis makes negatively charged histone able to
bind with DNA containing positive centers. In this way DNA remain in compact form with
histone proteins. Therefore the transcription or replication enzymes and cofactors not able to
bind such compact DNA structure. Histone deacetylase inhibition results into inhibition of
various transcription activities which may get accelerated during cancer development. The aim
of proposed study is to develop effective isoform selective Histone deacetylase inhibitor.
Synthesis of N-(2-Aminophenyl)-3-Quinolin-4-yl-Prop-2-Enamide derivatives from isatin and
its derivatives was achieved. Synthesis was carried out in two steps with good yield. 21
Compounds were synthesized and found to be effective with IC50s in between 3.694 -
38.4µmol in human HCT-116, COLO 205 and COLO 320 DM colon cancer cells in vitro. For
the cytotoxicity activity study MTT assay method was adopted. Docking studies were
performed initially with HDAC8 enzyme using V-life MDS software for synthesized
compounds and had selected best fit molecules for synthesis. The synthesized molecules are
effective as colon anticancer agents.
Pharmacology Properties of Cicer arietinum L.
Authors: Keyimu Xiren Guli , Bozlar Magfiret Abduveli , Wulamujiang Aini
Published: November 2020

Food legumes are crops of the family Leguminosae, also called Fabacae.
They are mainly grown for their edible seeds and thus are also named grain legumes.
Based on world production estimates, Cicer arietinum L. (Chickpea) is the third most
important coldseason food legume after the common bean (Phaseolus vulgaris L.) and
pea (Pisum sativum L.). Chickpea is generally consumed as a seed food, being a good
source of protein and other essential human nutrients. Chickpea (Cicer arietinum L.)
has recently been shown to have antioxidant, antibacterial, anticancer and antidiabetic
activities. This article presents information on the chemical components of Chickpea
(Cicer arietinum L.), antioxidant, antibacterial and anticancer compounds are reviewed
in relation to potential medicinal uses.
Energy Efficient Multi-Path Routing Algorithm Using Gray System Theory for Improvement of Routing and Network Stability in Internet of Things
Authors: Khaleghnasab Rogayye , Bagherifard Karamolah , Nejatian Samad , Ravaei Bahman
Published: November 2020

Internet of things (IoT) is a network of smart things. This indicates the ability of these physical things to transfer information with other physical things. The characteristics of these networks, such as topology dynamicity and energy constraint, challenges the routing problem in these networks. Previous routing methods could not achieve the required performance in this type of network. Therefore, developers of this network designed and developed specific methods in order to satisfy the requirements of these networks. One of the routing methods is utilization of multi-path protocols which send data to its destination using routes with separate links. One of such protocols is AOMDV routing protocol. In this paper, this method is improved using gray system theory which chooses the best paths used for separate routes to send packets. To do this, AOMDV packet format is altered and some fields are added to it so that energy criteria, link expiration time, and signal to noise ratio can also be considered while selecting the best route. The proposed method named RMPGST-IoT is introduced which chooses the routes with highest rank for concurrent transmission of data, using a specific routine based on the gray system theory. In order to evaluate and report the results, the proposed RMPGST-IoT method is compared to the ERGID and ADRM-IoT approaches with regard to throughput, packet receiving rate, packet loss rate, average remaining energy, and network lifetime. The results demonstrate the superior performance of the proposed RMPGST-IoT compared to the ERGID and ADRM-IoT approaches.
Molecular Epidemiology Characteristics of Brucella abortus Strains in China and Their Relationships with World Lineages
Authors: Wang Xu-ming , Zhao Zhong-zhi , wang miao , cui buyun , Liu Zhi-guo , Li zhen-jun
Published: November 2020

Brucella abortus is a facultative intracellular Gram-negative bacterium that causes chronic persistent infections in humans and livestock. In this study, conventional bio-typing, multiple-locus variable-number tandem repeat analysis (MLVA), and whole-genome sequencing-single-nucleotide polymorphism (WGS-SNP) were used to investigate the molecular epidemiology characteristics of Brucella abortus strains in China and their relationships to world lineages. A total of 100 strains were collected from 1953 to 2013, suggesting that B. abortus circulated in China in the past five decades. Moreover, most strains were mainly distributed in the northwest area. During this period, seven biovars were found, indicating that B. abortus displayed a high diversity of biovars and that the main epidemic areas are in the northern provinces. Strains have high genetic diversity, and bruce07 is the most helpful locus for genotyping of this population. Moreover, 17 MLVA-11 genotypes were found; 13 of them are of known genotypes and four are unassigned genotypes, indicating that B. abortus in this study had several geographic origins. Still, strains from unassigned genotypes may originate from China. Many shared MLVA-16 genotypes were observed in strains from the same provinces in Northern China, which confirmed a brucellosis outbreak within northern regions. WGS-SNP analysis showed that eight Chinese strains formed a ladder-like phylogram (C. Ⅶ) with strains from nine countries, including Uganda, Iraq, Russia, Georgia, Spain, Italy, Egypt, Mongolia, and China; strains were introduced to these countries from a single source. Notably, Chinese strains were closely related to strains from Russia and Mongolia; frequent animal (cattle) trade and exchanges may promote this process. We will provide new and insightful information for strength surveillance and control of B. abortus brucellosis in China.
The impact of IPP on GTI from the perspective of independent R&D
Authors: Yang Zijie , Huang Dong , Wang Yanzhen , Zhao Yuqing
Published: November 2020

Due to the continuous trade friction between China and the United States, for domestic enterprises in China, the cost of importing foreign technologies is increasing. Thus, the independent research and development (R&D) becomes particularly important for the realization of green technology innovation (GTI). This paper establishes a non-linear mediating effect model based on the data of various regions in China from 2012 to 2018. The main results are shown in the following. Firstly, there is an inverted U-shaped relationship between the intensity of intellectual property protection (IPP) and the level of GTI. Furthermore, the independent R&D investment has a masking effect between them. Secondly, by taking the independent R&D investment as a threshold variable, we prove our findings. Considering that the intensity of IPP is at a high level in most regions of China, the above statements mean that the enterprises need to continuously increase their investment in R&D, in order to further improve the regional ability in GTI. Meanwhile, local governments should also stimulate enterprises' willingness to expand their scale in R&D by issuing incentive policies, such as R&D tax incentives and government subsidies.
Africa’s Response Mechanisms to the Ramification of COVID-19
Authors: Ezeh Chinenye , Monkam Patrice , Amatus Gyilbag , Magoua Joseph Jonathan , Namusamba Mwichie , Babuna Pius
Published: November 2020

The ongoing crisis of COVID-19 pandemic that swept across the world, poses serious challenges on health delivery systems particularly in developing countries. In Africa however, the crisis rather inspires and sparks creativity and innovation at the national, institutional, organizational, and individual levels. This paper unravels Africa’s response mechanisms to the virus that might have relatively contributed to the low infection rate of the pandemic within the continent. Some criteria are adopted to assess and assemble the most influential government policies and home-grown innovations from various African countries and territories within the continent. It is found that, some of the innovations do not only help in combating the virus, but also have socio-economic benefits as they substantially complement government efforts in easing the burden of the citizenry as they cope with preventive protocols imposed on them. This study will be helpful in identifying the most significant home-based innovations that can be improved and used to reduce health delivery crises within the continent even after COVID-19.
Roles Of HIF and 2-Oxoglutarate Dependent Enzymes in Controlling Gene Expression In Hypoxia
Authors: Frost Julianty , Frost Mark , Batie Michael , Jiang Hao , Rocha Sonia
Published: November 2020

Hypoxia — reduction in oxygen availability—plays key roles in both physiological and pathological processes. Given the importance of oxygen for cell and organism viability, mechanisms to sense and respond to hypoxia are in place. A variety of enzymes utilise molecular oxygen, but of particular importance to oxygen sensing are the 2-oxoglutarate (2-OG) dependent dioxygenases (2-OGDs). Of these, Prolyl-hydroxylases have long been recognised to control the levels and function of Hypoxia Inducible Factor (HIF), a master transcriptional regulator in hypoxia, via their hydroxylase activity. However, recent studies are revealing that dioxygenases are involved in almost all aspects of gene regulation, including chromatin organisation, transcription and translation. We highlight the relevance of HIF and 2-OG dioxyenases in the control of gene expression in response to hypoxia and their relevance to human cancers.
LOGISTIC PERFORMANCE INDEX OF OECD MEMBERS
Authors: ATALAN Abdulkadir
Published: November 2020

Logistics Performance Index (LPI) values of the countries are considered in order to show the development levels of the countries' logistics infrastructure. In this study, the LPI values of the next period were calculated by considering the current LPI values of OECD members. Estimation series method was developed by using nonlinear equations for this study. The estimation data differed according to the degree of reliability of the equations. Estimated LPI data ranged from 2.869 to 4.206 with an average value of 3.611 based on equations. According to developed method of the study, the maximum value of LPI was estimated for Sweden, while the lowest value of LPI was determined for Slovenia among the members of OECD. In brief, a significant decrease in the estimated LPI values was observed in the majority of OECD members.
Smoking-Free Policies and Smoking Behaviors among Historically Black Colleges and Universities Students in the United States
Authors: Martin Elijah K. , Jacobson Lea , Singh Gopal K. , Sheikhatari Payam , Girmay Mehrete
Published: November 2020

Background:

There is limited research on the impact of smoke-free policies on students' attitudes and smoking behaviors at Historically Black Colleges and Universities (HBCUs) in the United States. This study examined African American students' attitudes toward differential smoke-free campus policies and their smoking behavior at two HBCUs in the Mid-Atlantic region.

Methods:

In this original study, 202 African American undergraduate and graduate students enrolled at two urban HBCUs participated and completed the online and in-person surveys conducted between October and December 2019. Descriptive statistics (Chi-square x2 and t-statistics) and multivariable logistic regression were used to examine differences in smoking attitudes and behaviors prompted by smoking-free policies.

Results:

One of the two surveyed HBCUs supported a comprehensive smoke-free policy (CSFP), which prohibits any tobacco use, including smoking, anywhere on campus at any time. The other HBCU followed a regular smoke-free policy (RSFP), which limits smoking to certain designated areas. The majority of students at the two schools reported that the smoke-free policy had not affected their smoking behavior. The multivariable analysis did not indicate a statistically significant association between students' attitudes toward smoke-free policies and their smoking behavior. Furthermore, the difference in smoking prevalence between the two schools was not statistically significant by policy type.

Conclusions and Implications for Translation:

Smoke-free polices have the potential to educate students about the risk of smoking and improve their attitudes about it. Implementing and enforcing a comprehensive or regular smoke-free policy is an essential step toward providing a healthy learning environment for students. Understanding the context-specific factors that contribute to smoking behaviors among African American students would provide additional important insights to policymakers in developing more effective programs for students at HBCUs.
Zero Point Content
Authors: Potrč Matjaž
Published: November 2020

Strategija je najprije predstaviti uobičajene pristupe sadržajne atomističke potpunosti, u njihovim okurentnim i dispozicijskim oblicima.
Zatim, sažima se semantički tretman fokalne točke. Razlika se može objasniti radom kromatičke iluminacije iz izvanjske lokalne informacije,
pozivajući strma okruženja u pozadini kognitivnog pejzaža, u dva smjera. Prvo, uzima se u obzir izvanjska informacija, čime se dolazi do potpunog kognitivnog stanja nedimenzionalne točke u srednjoj razini opisa kognitivnog sustava. Na gornjoj razini opisa, sadržaj totalnog kognitivnog stanja zaprima svoje iskustveno bogatstvo iz više karakteristika prisutnih u spomenutom lokalnom okruženju, te su u njemu prihvaćene, bez čega bi bile eksplicitno reprezentirane u svijesti epistemičkog agenta. Neuspjeh drugog koraka vodi do obveze na eksplicitnu predodžbu sadržaja. Usporedno, neuspjeh primjene kromatičke iluminacije na izvanjsku informaciju vodi do strategija eksternalističke
semantičke fokalne točke.
Rival Concepts of Courage
Authors: Calvert Anita
Published: November 2020

Aristotelove misli o hrabrosti u Nikomahovoj etici i dalje su najučestalije štivo rasprava o vrlini. Međutim, ako primijenimo razmatranje o vrlinama Alasdaira MacIntyrea, postavlja se pitanje o tome
raspolažemo li u suvremenim liberalnim društvima tek fragmentima drevnog pojma hrabrosti. Slika hrabrosti izmijenila se. Možemo govoriti o
aristotelovskim uvidima i pričati o srednjovječnim vitezovima, ali sadašnja su tradicija i karakter njena morala ti što oblikuju naše razumijevanje i korištenje vrlina. MacIntyreovski trostruki pristup vrlinama, uzimajući u obzir a) praksu, b) pripovjedno jedinstvo života i
c) tradiciju, otkriva dva suparnička pojma hrabrosti: vrlina hrabrosti izvrsnosti i vrlinu hrabrosti učinkovitosti. Koja će prevladati ovisi o tome kakvu ćemo hrabrost usvojiti kao našu drugu prirodu navike.
Against Epistemological Virus of Scepticism
Authors: Šljivo Kenan
Published: November 2020

Ovaj rad daje kratak pregled pristupa epistemološkim pitanjima koja u svom učenju zastupa američki filozof Donald Davidson. U pitanju je pokušaj da se putem analize temeljnih Davidsonovih postavki pokuša načiniti okvir za razumijevanje jedne vrlo autentične epistemološke pozicije i načina na koji se ona pojavljuje kao antipod skeptičkim epistemološkim strategijama. Drugim riječima, želi se u formi skupa postulata identificirati koordinatni sistem iz kojeg Davidson projektira
svoje epistemološke stavove. U tu je svrhu u radu prikazan razvojni proces Davidsonove epistemološke misli, koji ide kroz triangulaciju pojmova subjektivno, intersubjektivno i objektivno. Ono što je u radu posebno osvijetljeno jest Davidsonov okret prema komunikativnim praksama
i intersubjektivnosti kao jedinim toposima u kojima se pitanje o objektivnosti znanja može uopće postaviti.
An exploratory study on factors associated with consumers’ post-purchase dissonance of electric vehicles
Authors: Khraim Hamza
Published: November 2020

Consumers’ post-purchase dissonance usually instigates after the purchase decisions are considered extremely important for marketers, resulting in severe consequences on consumer satisfaction and switching behavior. The current study aims to investigate the potential effect of consumer knowledge of electric vehicles (EVs), perceived risk, functional characteristics of EVs, attitude towards EVs on consumer post-purchase dissonance. The paper uses a quantitative approach by designing and distributing an online questionnaire to respondents. A total of 268 respondents participated and filled the online questionnaire. The data analysis revealed that functional characteristics emerge to be the leading factor per the consumer’s response, followed by perceived risk. The hypotheses testing results showed that functional characteristics, knowledge, and attitude have a statistically significant effect on post-purchase dissonance while concerning the perceived risk of EV. The results show that it has no statistically significant influence on post-purchase dissonance. Based on the results, it is critical to enhance consumer knowledge about the functional characteristics of electric vehicles to create a positive attitude that contributes to reducing post-purchase dissonance.
Türkiye’de Yaşayan Iraklı Göçmenlerin Deizm ve Ateizme Yönelik Tutumları
Authors: Ghraırı Mohammed , Peker Hüseyin
Published: November 2020

Irak, Antik çağlardan günümüze kadar onlarca medeniyete ve devlete ev sahipliği yapmıştır. Osmanlı İmparatorluğu’ndan ayrıldıktan sonra günümüze kadar birçok savaşlar ve darbeler atlatan Irak’ta özellikle Körfez Savaşları’ndan sonra komşu ülkelere kitlesel göçler başlamıştır. Bu araştırma makalesi kapsamında, Türkiye’ye göç eden Iraklı göçmenlerin dini yönelim ölçeği ekseninde, deizm ve ateizme yönelik tutumları sayısal veriler ile analiz edilmiştir. Göçmenlik, mültecilik gibi olguların din psikolojisi üzerine etkileri araştırılmıştır. 19. yüzyılın belirli dönemlerinde birçok disiplinin araştırma konusu olan din olgusundan hareketle, tarihsel olaylar ve değişen yaşam koşulları çerçevesinde din olgusunun ve dindarlığın tartışılıp ölçülebilmesi de din psikolojisinin farklı boyutlarına etki etmektedir. Türkiye’de yaşayan Iraklı göçmenlerin deizm ve ateizme yönelik tutumlarının ölçülmesi de bu araştırma kapsamı çerçevesinde hazırlanmıştır ve veri toplama yöntemleri kullanılarak kapsamlı bulgular elde edilmiştir. Elde edilen veriler analiz edilerek Türkiye’deki Iraklı göçmenlerin, deizme ve ateizme yönelik yaklaşım ve tutumları incelenmiş, din psikolojisi kapsamındaki yönelimleri araştırılarak bulgular halinde sunulmuştur.
An Overview of Targeting Legumain for Inhibiting Cancers
Authors: Reddy Bandi D. , Beeraka Narasimha M. , Chitturi CH. M. Kumari , Madhunapantula SubbaRao V.
Published: November 2020

Legumain (LGMN; EC: 3.4.22.34), an asparaginyl endopeptidase (AEP) or asparaginyl carboxypeptidase
(ACP), is a member of the C13 family of cysteine proteases. Elevated expression of LGMN is reported
not only in the tumor cells of breast, prostate, and liver but also in the macrophages of the tumor microenvironment.
Hence, LGMN is considered as a key protein involved in the regulation of tumor angiogenesis,
invasion, and metastasis. Targeting LGMN using siRNA or pharmacological agents and peptides was reported
to reduce cancer cell proliferation in vitro and shrink tumor size in vivo. Moreover, expression of LGMN is significantly
low in normal cells compared to tumor cells or tumor-associated macrophages (TAMs); hence, legumain
can be used as a marker for tumor recognition and targeting. Therefore, approaches inhibiting LGMN expression
or activity are more viable, less toxic, and help in developing the targeted therapeutics. However, to
date, LGMN targeting strategies have not been well reported. In this review, an attempt was made to summarize
articles pertaining to LGMN (a) structure and activity; (b) oncogenic nature; (c) pharmacological inhibitors; and
(d) targeting approaches that inhibit tumor growth. Furthermore, a list of existing gaps in LGMN research is
highlighted, which needs additional studies.
Anti-allergic Assessment of Ethanol Extractives of Quisqualis Indica Linn
Authors: Chaudhary Deepa , Srivastava Rajnish , Nagar Hemant
Published: November 2020

Aim:

The present work was aimed at finding out the anti-allergic activity of ethanol extracts of Quisqualis indica Linn. (EEQI) by in-vitro and in-vivo murine models.

Background:

Worldwide, the rise in the prevalence of allergic diseases has continued in the industrialized world for more than 50 years. About 0.05-2% of the population is estimated to experience anaphylaxis at some point in life. Quisqualis indica Linn in an ornamental plant that has been rarely used as a herbal medicine, however, the presence of polyphenols and flavonoids have been reported to possess anti-inflammatory, antipyretic and immunomodulatory activity, which have some pathological relevance with anaphylaxis.

Objective:

The objective of the present research was to investigate, scientifically explore and understand the probable anti-anaphylactic mechanism of ethanol extracts of Quisqualis indica Linn. via different preclinical models.

Material and Method:

In-vitro study was done on de-granulated mesenteric mast cells induced by compound 48/80 and in-vivo study was done by Passive Cutaneous Anaphylaxis (PCA) model. In the in-vitro study degranulated mesenteric cells were grouped into negative control (compound 48/80 treated), positive control (Disodium cromoglycate + 48/80 treated) and 3 test groups (EEQI 10 μg/ml + 48/80 treated, EEQI 50 μg/ml + 48/80 treated and EEQI 100 μg/ml + 48/80 treated). The number of degranulated mast cells was counted and compared within the different treatment groups. In the in-vivo study, the rats were first grouped into negative control (vehicle only), positive control (Disodium cromoglycate) and 2 test groups (EEQI: 100 and 200 mg/kilogram). The animals were pretreated for 12 days. On the 12th day, all the rats were immunized with serum anti-ovalbumin (obtained from an already sensitized rat) by the intradermal route. After 24 h of serum injection, Evans blue dye containing oval albumin was administered intravenously in all groups. Three days later, the rats were taken down for the severity of the anaphylactic reactions.

Result:

EEQI significantly attenuates mast cell degranulation and maintains cell intactness as compared to control (P < 0.001). It was set up to support the degree of anaphylaxis as compared to the control group (P < 0.001).

Conclusion:

The outcomes of the work revealed the preventive effect of Quisqualis indica Linn. against allergic manifestations.
Childhood Infectious Encephalitis: An Overview of Clinical Features, Investigations, Treatment, and Recent Patents
Authors: Au Cheuk C. , Hon Kam L. , Leung Alexander K.C. , Torres Alcy R.
Published: November 2020

Background::

Infectious encephalitis is a serious and challenging condition to manage.
This overview summarizes the current literature regarding the etiology, clinical manifestations, diagnosis,
management, and recent patents of acute childhood infectious encephalitis.

Methods::

We used PubMed Clinical Queries as a search engine and used keywords of “encephalitis”
AND “childhood” Patents were searched using the key term “encephalitis” in google.patents.-
com and patentsonline.com.

Results::

Viral encephalitis is the most common cause of acute infectious encephalitis in children.
In young children, the clinical manifestations can be non-specific. Provision of empiric antimicrobial
therapy until a specific infectious organism has been identified, which in most cases includes
acyclovir, is the cornerstone of therapy. Advanced investigation tools, including nucleic acid-based
test panel and metagenomic next-generation sequencing, improve the diagnostic yield of identifying
an infectious organism. Supportive therapy includes adequate airway and oxygenation, fluid
and electrolyte balance, cerebral perfusion pressure support, and seizure control. Recent patents are
related to the diagnosis, treatment, and prevention of acute infectious encephalitis.

Conclusions::

Viral encephalitis is the most common cause of acute infectious encephalitis in children
and is associated with significant morbidity. Recent advances in understanding the genetic basis
and immunological correlation of infectious encephalitis may improve treatment. Third-tier diagnostic
tests may be incorporated into clinical practice. Treatment is targeted at the infectious process
but remains mostly supportive. However, specific antimicrobial agents and vaccines development
is ongoing.
Risk Factors for Gender-Based Violence among Female Students of Gonder Teacher’ Training College, Gonder, Northwest Ethiopia: A Cross-Sectional Study
Authors: Birkie Mengesha , Zenebe Yosef , Biset Gebeyaw , Gebresellassie Moges , Mihret Setegn
Published: November 2020

Background:

Violence against women is the world's most prevalent, pervasive and enduring problem. Sexual violence appears to be particularly great among adolescent girls of Sub-Saharan African countries, including Ethiopia.

Methods:

A cross-sectional survey was conducted from January to February 2018, and 322 participants were selected via a stratified sampling technique. Data were entered using Epi-data version 3.1 and exported to SPSS version 21 for analysis, then bivariate and multivariate logistic regression was employed to see statistically significant factors.

Results:

Lifetime prevalence of Gender-based violence was found to be 35.1% (95% CI: 29.9 - 40.3). Risk factors significantly associated with sexual violence were living alone (AOR = 4.3 95% CI: 1.03, 18.09), having two or more number of sexual partner in life (AOR = 11.5 95% CI: 2.80, 47.16), lack of open discussion between parents and daughters about reproductive health issues (AOR= 5.05 95% CI: 1.37, 18.55), being third year student 9.06(1.96, 41.94), strict parenting style over the girls behavior (AOR = 3.4 (1.04,10.72), alcohol consumption (AOR = 8.3 95% CI: 2.57, 27.00), use of khat (AOR = 11.05 95% CI: 3.53, 34.60), and monthly financial support to the girls from family (AOR= 0.1, 95% CI: (0.03, 0.73).

Conclusion:

The prevalence of Gender-based violence among female college students in Gonder town was high. Attention should be paid to the reduction of the prevalence and those risk factors of Gender-based violence.
Analysis of HIV/AIDS Integration into the Academic Curriculum at a Selected University in South Africa
Authors: Murwira Success Tinotenda , Base Khoza Lunic , Mabunda Jabu Tsakani , Maputle Sonto Maria , M. Peta Mamotema
Published: November 2020

Background:

Although there is evidence that education is a social weapon in the fight against HIV/AIDS, there is also evidence that, to date, HIV/AIDS is not fully integrated into all the disciplines in Higher Education Institutions (HEIs). Therefore, most of the university students in South Africa are not well prepared to be HIV/AIDS-competent graduates who can live and work in a society ravaged by AIDS.

Objective:

This study sought to analyse the extent of HIV/AIDS integration into the curricula in various departments at a selected university in the Limpopo Province, South Africa.

Materials and Methods:

The study used quantitative and qualitative approaches to analyse the extent of HIV/AIDS integration into the curricula. The curriculum calendars were retrieved from the university website. An audit tool guided retrieval of HIV/AIDS content and was analysed using SPSS V 25. The qualitative content analysis was used to describe the nature of HIV/AIDS content.

Results:

Out of eight schools, about 68 modules had HIV/AIDS content. The majority of the modules (53; 78%) were offered at the undergraduate level. Furthermore, the majority of the HIV/AIDS content (62; 91%) was integrated into undergraduate compulsory modules. Most (34; 51%) of the HIV/AIDS content were located in health sciences disciplines. HIV/AIDS content was mostly integrated into existing carrier modules. Time allocation for the teaching of HIV/AIDS was not indicated. Most of the modules did have information about teaching and assessment strategies.

Conclusion:

It is recommended that discipline-specific HIV/AIDS content be integrated into all disciplines.
Polysarcosine: The Best Alternative of Poly (Ethylene Glycol)
Authors: Singhai Manu , Bhattacharya Sankha
Published: November 2020

Polysarcosine (psar) is a non-ionic hydrophilic polypeptoid with numerous biologically
relevant properties. Polysarcosine is poly (n-methylated glycine) and has been reported first by
Weslay and co-workers in the 1920s. Polysarcosine was first synthesized via ring-opening polymerization
(rop) of sarcosine n-carboxyanhydride, using high-vacuum techniques. Overall, findings
highlight the potential of poly(sarcosine) as an alternative corona-forming polymer to poly (ethylene
glycol)-based analogues of (polymerization-induced self-assembly) pisa assemblies for use in
various pharmaceutical and biomedical applications. Numerous studies suggested that such polypeptoids
hold enormous potential for many biomedical applications, including protein delivery,
colloidal stabilization, and nanomedicine.
NILAI-NILAI EKOLOGI DALAM “PEGASUS JATUH” DAN PENGGUNAANNYA DALAM PEMBELAJARAN SASTRA
Authors:   IAIN Tulungagung, Hakim Titik Dwi Ramthi , Fahmi Nifa Kurnia , Ilmia Wakhidatul
Published: November 2020

The purpose of this study, first, is to analyze the echocritical element reflected by the author through the short story Pegasus Jatuh. Second, integrate ecological values in literature teaching. This study used descriptive qualitative method. The approach used is Garrard's eco-criticism. Sources of data obtained from the behavior of characters in the short story. Data analysis begins by marking words, phrases, clauses, and sentences that have a focus on environmental exploitation. The results show in the short story “Pegasus Jatuh”, the author reflects environmental phenomena that include illegal logging, buying and selling protected animals, and exploitation of gold. The analysis applied in literature learning which has an important role in character education. Literature in education has a role to develop the language, cognitive, affective, psychomotoric, personality, and social aspects of students.
MITOLOGI SENI REYOG PONOROGO VS KAMPANYE PERLINDUNGAN SATWA ANIMAL WALFARE MELALUI PRAKTIK REKAYASA SOSIAL
Authors:   Program Studi Ilmu Pemerintahan, Fakultas Ilmu Sosial dan Ilmu Politik, Universitas Muhammadiyah Ponorogo, Harsono Jusuf , Santoso Slamet ,   Program Studi Ekonomi Pembangunan, Fakultas Ekonomi, Universitas Muhammadiyah Ponorogo, Hilman Yusuf Adam ,   Program Studi Ilmu Pemerintahan, Fakultas Ilmu Sosial dan Ilmu Politik, Universitas Muhammadiyah Ponorogo
Published: November 2020

Community beliefs in using tiger’s skin considered as an important thing for Ponorogo’s Reyog artist. However, this intensely opposed to Animal Welfare Conception. Therefore, it needs against the reality of deconstruction. This study seeks to change the Ponorogo’s Reyog artist mindset. It can be change slowly by Social Engineering. This study using a qualitative methodology with the approach of phenomenology. Informants in this review are craftsman of Reyog and the artist. The study obtained the procedure of making craft, Dhadhak Merak (Barongan). By using substitute material, the cost are difference. It is cheaper. The dissemination of information through media-related making craft Dhadhak Merak (Barongan) Subtitusi made. Through the medium of as a newspaper, that readily in were missing by the community is a form of campaign As Social-Engineering practices of measurable.
A Web-Based Game for Young Adolescents to Improve Parental Communication and Prevent Unintended Pregnancy and Sexually Transmitted Infections (The Secret of Seven Stones): Development and Feasibility Study
Authors: Shegog Ross , Armistead Laura , Markham Christine , Dube Sara , Song Hsing-Yi , Chaudhary Pooja , Spencer Angela , Peskin Melissa , Santa Maria Diane , Wilkerson J Michael , Addy Robert , Tortolero Emery Susan , McLaughlin Jeffery
Published: November 2020

Background

Early adolescent unintended pregnancy and sexually transmitted infection prevention are significant public health challenges in the United States. Parental influence can help adolescents make responsible and informed sexual health decisions toward delayed sexual debut; yet parents often feel ill equipped to communicate about sex-related topics. Intergenerational games offer a potential strategy to provide life skills training to young adolescents (aged 11-14 years) while engaging them and their parents in communication about sexual health.

Objective

This study aims to describe the development of a web-based online sexual health intergenerational adventure game, the Secret of Seven Stones (SSS), using an intervention mapping (IM) approach for developing theory- and evidence-based interventions.

Methods

We followed the IM development steps to describe a theoretical and empirical model for young adolescent sexual health behavior, define target behaviors and change objectives, identify theory-based methods and practical applications to inform design and function, develop and test a prototype of 2 game levels to assess feasibility before developing the complete 18-level game, draft an implementation plan that includes a commercial dissemination strategy, and draft an evaluation plan including a study design for a randomized controlled trial efficacy trial of SSS.

Results

SSS comprised an adventure game for young adolescent skills training delivered via a desktop computer, a text-based notification system to provide progress updates for parents and cues to initiate dialogue with their 11- to 14-year-old child, and a website for parent skills training and progress monitoring. Formative prototype testing demonstrated feasibility for in-home use and positive usability ratings.

Conclusions

The SSS intergenerational game provides a unique addition to the limited cadre of home-based programs that facilitate parent involvement in influencing young adolescent behaviors and reducing adolescent sexual risk taking. The IM framework provided a logical and thorough approach to development and testing, attentive to the need for theoretical and empirical foundations in serious games for health.