bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolutionary and Biogeographical History of Penguins (Sphenisciformes): Review of the Dispersal Patterns and Adaptations in a Geologic and Paleoecological Context
Authors: Pelegrín Jonathan S. , Acosta Hospitaleche Carolina
Published: March 2022

Despite its current low diversity, the penguin clade (Sphenisciformes) is one of the groups of birds with the most complete fossil record. Likewise, from the evolutionary point of view, it is an interesting group given the adaptations developed for marine life and the extreme climatic occupation capacity that some species have shown. In the present contribution, we reviewed and integrated all of the geographical and phylogenetic information available, together with an exhaustive and updated review of the fossil record, to establish and propose a biogeographic scenario that allows the spatial-temporal reconstruction of the evolutionary history of the Sphenisciformes, discussing our results and those obtained by other authors. This allowed us to understand how some abiotic processes are responsible for the patterns of diversity evidenced both in modern and past lineages. Thus, using the BioGeoBEARS methodology for biogeographic estimation, we were able to reconstruct the biogeographical patterns for the entire group based on the most complete Bayesian phylogeny of the total evidence. As a result, a New Zealand origin for the Sphenisciformes during the late Cretaceous and early Paleocene is indicated, with subsequent dispersal and expansion across Antarctica and southern South America. During the Eocene, there was a remarkable diversification of species and ecological niches in Antarctica, probably associated with the more temperate climatic conditions in the Southern Hemisphere. A wide morphological variability might have developed at the beginning of the Paleogene diversification. During the Oligocene, with the trends towards the freezing of Antarctica and the generalized cooling of the Neogene, there was a turnover that led to the survival (in New Zealand) of the ancestors of the crown Sphenisciform lineages. Later these expanded and diversified across the Southern Hemisphere, strongly linked to the climatic and oceanographic processes of the Miocene. Finally, it should be noted that the Antarctic recolonization and its hostile climatic conditions occurred in some modern lineages during the Pleistocene, possibly due to exaptations that made possible the repeated dispersion through cold waters during the Cenozoic, also allowing the necessary adaptations to live in the tundra during the glaciations.
Importance of Mangroves for Bat Research and Conservation: A Case Study from Vietnam with Notes on Echolocation of Myotis hasselti
Authors: Thong Vu Dinh , Denzinger Annette , Long Vu , Sang Nguyen Van , Huyen Nguyen Thi Thu , Thien Nguyen Hoang , Luong Nguyen Khanh , Tuan Le Quang , Ha Nguyen Manh , Luong Nguyen Thanh , Schnitzler Hans-Ulrich
Published: March 2022

Mangrove ecosystems play important ecological roles, including the mitigation of global climate change and biodiversity conservation. However, they have received little attention from scientists for the research and conservation of bats and general biodiversity. In Vietnam, bat species inhabiting mangroves have been relatively unstudied, while this ecosystem is located along the country’s coastal zones and has declined dramatically due to the development of agriculture, wind energy and other threats. To initially fill this gap, five bat surveys were conducted between September 2019 and November 2021 within Ha Long Bay and Ben Tre province, which contain representative mangrove areas of northern and southern regions of Vietnam, respectively. Bats were captured using mist nets, mobile nets and hand nets. Their echolocation calls were recorded and analyzed using the PCTape system and Selena software, respectively. Five species were captured and recorded: Cynopterus brachyotis, Macroglossus minimus, Myotis hasselti, Myotis pilosus and Taphozous melanopogon. They are all new to both Ha Long Bay and Ben Tre province. Four species (C. brachyotis, M. minimus, M. hasselti and M. pilosus) have been rarely documented from other ecosystems in Vietnam but have commonly been recorded and captured in mangrove areas. Of these species, M. pilosus is a globally “Vulnerable” species. While searching for prey, Myotis hasselti emitted high energy echolocation calls sweeping from about 96 to about 24 kHz with a signal duration of about 5 ms. This species sometimes uses social calls of a horseshoe-shaped structure, which last about 15 ms and are emitted about 26 ms in front of a search call. Results from our surveys indicated the importance and potential of mangroves for bat research and conservation.
Efficient Garbage Collection Algorithm for Low Latency SSD
Authors: Ae Jin , Hong Youpyo
Published: March 2022

Solid-state drives (SSDs) are rapidly replacing hard disk drives (HDDs) in many applications owing to their numerous advantages such as higher speed, low power consumption, and small size. NAND flash memories, the memory devices used for SSDs, require garbage collection (GC) operations to reclaim wasted storage space due to obsolete data. The GC is the major source of performance degradation because it greatly increases the latency for SSDs. The latency for read or write operations is sometimes significantly long if the operations are requested by users while GC operations are in progress. Reducing the frequency of GC invocation while maintaining the storage space requirement may be an ideal solution to remedy this problem, but there is a minimal number of GC operations to reserve storage space. The other approach is to reduce the performance overhead due to GC rather than reducing GC frequency. In this paper, following the latter approach, we propose a new GC scheme that reduces GC overhead by intelligently controlling the priorities among read/write and GC operations. The experimental results show the proposed scheme consistently improve the overall latency for various workloads.
Organic Petrological Characteristics of Graptolite and Its Contribution to Buried Organic Carbon of Longmaxi Formation Shales, Middle Yangtze Region
Authors: Li Wenhao , Wang Xiuzhe , Wang Min , Yang Erqiang
Published: March 2022

The shale gas exploration of the Longmaxi Formation in the Yangtze Region of China has made a significant breakthrough. As an important hydrocarbon generation organism, graptolite is widely distributed in the Longmaxi Formation shales, but its hydrocarbon potential is still unclear. Taking the Longmaxi Formation shales in the Middle Yangtze Region as an example, this paper discusses the organic petrological characteristics of graptolite and its contribution to buried organic carbon. The Longmaxi shales in the study area can be divided into organic-rich shales (TOC > 2.0%) and organic-bearing shales (TOC < 2.0%). The organic-rich shales have high quartz content and low clay mineral content, which is opposite in the organic-bearing shales. Organic maceral results show that graptolite is widely distributed in nearly all the samples, while solid bitumen is relatively developed in organic-rich shale. The equivalent vitrinite reflectance obtained from the conversion of graptolite reflectance ranges from 2.46% to 2.76%, indicating that the organic matter maturity of the Longmaxi Formation shale is overmature. Combining an optical microscope and a field emission scanning electron microscope, the proportion of graptolite area to organic matter area can be obtained, the average of which is 32.71%. Solid bitumen mainly contributes to buried organic carbon of the organic-rich shales in the Longmaxi Formation, while graptolites contribute little to organic carbon burial. However, solid bitumen in the organic-bearing shales is relatively undeveloped, and graptolite is an important hydrocarbon generation organism, which is the main contributor to buried organic carbon.
Molecular Simulation Study and Analytical Model for Oil–Water Two-Phase Fluid Transport in Shale Inorganic Nanopores
Authors: Zhang Wei , Feng Qihong , Wang Sen , Zhang Xianmin , Zhang Jiyuan , Cao Xiaopeng
Published: March 2022

Shale reservoirs contain omnipresent nanopores. The fluid transport phenomena on the nanoscale are significantly different from that on the macroscale. The understandings of fluid transport behavior, especially multiphase flow, are still ambiguous on the nanoscale and the traditional hydrodynamic models are insufficient to describe the fluid flow in shale. In this work, we firstly use a molecular dynamics simulation to study the oil–water two-phase flow in shale inorganic quartz nanopores and investigated the unique interfacial phenomena and their influences on fluid transport in a confined nanospace. The results of the molecular simulation revealed that the water-oil-water layered structure was formed in quartz nanopores. There is no-slip boundary condition between water and quartz surface. The density dip and the extremely low apparent viscosity of the oil–water interface region were observed. The liquid–liquid slip effect happened at the oil–water interface. Based on the nano-effects obtained by the molecular simulation, two mathematical models were proposed to describe the nanoscale oil–water two-phase flow, considering both the solid–liquid and liquid–liquid interfacial phenomena, and the performances of two mathematical models were validated. This study shed light on the flow behaviors of oil and water on the nanoscale, and provides the theoretical basis for scale-upgrading, from the nanoscale to the macroscale.
Economic Evaluation of Implementation of Power-to-Gas: Application to the Case of Spain
Authors: Abánades Alberto , Frías Jesús
Published: March 2022

An economic analysis of the implementation of the power-to-gas (PtG) system between 2030 and 2055 is presented at a large scale. The capacity of the PtG system is adapted to two scenarios in Spain (Bailera and Lisbona 2018), corresponding to growing scenarios of 1.73 and 1.36%/y of its electricity market. The total power capacity of the PtG system has been fixed to 12.7 and 3.84 GW, respectively, at the end of 2055. The levelized cost of storage (LCOS) of the implementation of PtG has been evaluated. Assuming uncertainties in the current cost projections for CAPEX and OPEX, LCOS estimations are between 136 and 686 EUR/MWh with a payback time of 16 years in the best scenario for a reference electricity purchase of 100 EUR/MWh and a CO2 penalty of 100 EUR/ton. A sensitivity analysis and the viability dependence versus energy purchase and CO2 penalty certificates is shown. This work sheds some light for the comparison of PtG implementation costs in comparison with other storage options, such as batteries, pumped-storage hydroelectricity or compressed air storage for future energy scenarios.
Experiments on Single-Phase Nanofluid Heat Transfer Mechanisms in Microchannel Heat Sinks: A Review
Authors: Eneren Pinar , Aksoy Yunus Tansu , Vetrano Maria Rosaria
Published: March 2022

For more than 20 years, the use of nanofluids to enhance heat transfer in microchannel heat sinks (MCHSs) has been the subject of a large number of scientific articles. Despite the great potentialities reported in several works, the presence of controversial results and the lack of understanding of heat transfer enhancement mechanisms prevent further advancement in the use of nanofluids as coolants. This article reviews the scientific literature focused on several aspects of nanofluids that have a role in the heat transfer enhancement within the MCHSs: nanofluid stability, thermal conductivity, and particle clustering, as well as the particle–surface interactions, i.e., abrasion, erosion, and corrosion. We also include the most relevant works on the convective heat transfer and MCHSs operated with nanofluids in our review.
Reliability-Centered Maintenance Scheduling of Photovoltaic Components According to Failure Effects
Authors: Shin Joong-Woo , Yoon Kwang-Hoon , Chai Hui-Seok , Kim Jae-Chul
Published: March 2022

In the power distribution system of South Korea, the sectionalizer minimizes and recovers the system from failures, and prohibits independent operation of distributed energy resources. Therefore, it is difficult to expect reliability improvements owing to a photovoltaic system in the power distribution system. Herein, we propose a reliability-centered maintenance-scheduling method based on an economic analysis of photovoltaic integration facilities to ensure the economic feasibility of the photovoltaic system operator and the reliability of the power distribution system. Photovoltaic integration facilities are divided into two categories based on their spread of the failure, and the maintenance scheduling is evaluated according to the maximum and minimum losses according to the time of failure. Facilities that cause power outages to photovoltaics and to loads have relatively little effect on the time of failure. This is because the effects of the power outages in the loads predominate. In contrast, facilities that only cause photovoltaic outages are affected by the generation time. In particular, insulated gate bipolar transistors that operate only during photovoltaic generation have been found to be more economical for corrective replacement than preventive replacement.
Seismic Analysis of 10 MW Offshore Wind Turbine with Large-Diameter Monopile in Consideration of Seabed Liquefaction
Authors: Zhang Jian , Yuan Guo-Kai , Zhu Songye , Gu Quan , Ke Shitang , Lin Jinghua
Published: March 2022

With the increasing construction of large-scale wind turbines in seismically active coastal areas, the survivability of these high-rated-power offshore wind turbines (OWTs) in marine and geological conditions becomes extremely important. Although research on the dynamic behaviors of OWTs under earthquakes has been conducted with consideration of the soil-structure interaction, the attention paid to the impact of earthquake-induced seabed liquefaction on OWTs supported by large-diameter monopiles remains limited. In view of this research gap, this study carries out dynamic analyses of a 10 MW OWT under combined wind, wave, and earthquake loadings. This study uses a pressure-dependent multisurface elastoplastic constitutive model to simulate the soil liquefaction phenomenon. The results indicate that the motion of the large-diameter monopile leads to more extensive soil liquefaction surrounding the monopile, specifically in the zone near the pile toe. Moreover, compared with earthquake loading alone, liquefaction becomes more severe under the coupled wind and earthquake loadings. Accordingly, the dynamic responses of the OWT are apparently amplified, which demonstrates the importance of considering the coupling loadings. Compared with wind loading, the effect of wave loading on the dynamic response and liquefaction potential is relatively insignificant.
Hotspot-Aware Workload Scheduling and Server Placement for Heterogeneous Cloud Data Centers
Authors: Jamal M. Hasan , Chaudhry M. Tayyab , Tahir Usama , Rustam Furqan , Hur Soojung , Ashraf Imran
Published: March 2022

Data center servers located in thermal hotspot regions receive inlet air at a higher than the set temperature and thus generate comparatively high outlet temperature. Consequently, there is a rise in energy that is consumed to cool down the servers that otherwise would undergo reliability hazards. The workload deployment across the servers should be resilient to thermal hotspots to ensure smooth performance. In a heterogeneous data center environment, an equally important fact is the placement of the servers in a thermal hotspot-aware manner to lower the peak outlet temperatures. These approaches can be applied proactively with the help of outlet temperature prediction. This paper presents the hotspot adaptive workload deployment algorithm (HAWDA) and hotspot aware server relocation algorithm (HASRA) based on thermal profiling regarding outlet temperature prediction. HAWDA deploys workload on servers in a thermal-efficient manner and HASRA optimizes the server location in thermal hotspot regions to lower the peak outlet temperatures. Performance comparison is carried out to analyze the efficacy of HAWDA against the TASA and GRANITE algorithms. Results suggest that HAWDA provides average peak utilization of the servers similar to GRANITE and TASA without additional burden on the cooling mechanism, with and without server relocation, as HAWDA minimizes the peak outlet temperature.
Genome-Wide Identification and Expression Analysis of MYC Transcription Factor Family Genes in Rubber Tree (Hevea brasiliensis Muell. Arg.)
Authors: Zhang Shi-Xin , Wu Shao-Hua , Chao Jin-Quan , Yang Shu-Guang , Bao Jie , Tian Wei-Min
Published: March 2022

Myelocytomatosis (MYC) transcription factors play a core regulator in the jasmonic acid signaling pathway, which regulates the secondary laticifer differentiation and rubber biosynthesis in rubber tree (Hevea brasiliensis). However, there are currently no reports on the MYC gene family in rubber trees, an important industrial raw material crop worldwide. In the present study, 32 HblMYCs were isolated and identified. The diversity in gene structure and presence of various cis-regulatory elements in promotors suggest that HblMYCs participate in various biological processes. Based on the expression patterns in the cambium region and laticifer in, respectively, response to coronatine (COR) and tapping, and the phylogenetic relationship with the MYCs that have been functionally identified in other plants, the HblMYC24 and HblMYC30 may be related to laticifer differentiation while the HblMYC6, HblMYC11 and HblMYC15, as well as HblMYC16 and HblMYC21, may positively regulate rubber biosynthesis. The results provide a foundation for understanding the molecular mechanism of jasmonate signaling in regulating laticifer differentiation and rubber biosynthesis in rubber tree.
European Spruce Bark Beetle, Ips typographus (L.) Males Are Attracted to Bark Cores of Drought-Stressed Norway Spruce Trees with Impaired Defenses in Petri Dish Choice Experiments
Authors: Netherer Sigrid , Schebeck Martin , Morgante Giuseppe , Rentsch Verena , Kirisits Thomas
Published: March 2022

The European spruce bark beetle, Ips typographus (L.), is a major pest of Norway spruce. During outbreaks, the beetles can colonize moderately stressed trees via mass attacks mediated by aggregation pheromones, while at endemic population levels, beetles infest trees with impaired defenses. I. typographus introduces ophiostomatoid fungi into the phloem, which can support host colonization. Low-density fungal infections are locally contained by hypersensitive wound reactions; larger necrotic lesions indicate lower tree resistance. Here, we made links between drought stress, susceptibility to fungal infections, and the attractiveness of spruce for host-searching I. typographus males. We sampled bark cores from roofed, non-roofed and untreated control trees of a rainfall exclusion field site. Drought stress was assessed using pre-dawn twig water potentials, and tree defenses were assessed using inoculations with Grosmannia penicillata. Subsequently, we performed Petri dish arena choice tests in the lab, where male beetles could choose between the bark samples of differentially stressed trees. We found that the attractiveness of bark cores increased with drought stress and the extent of hypersensitive wound reactions to fungal infection. Furthermore, beetles stayed longer in those Petri dish sections with the sample of their final choice. The bioassays provide evidence for the primary attraction of male I. typographus to tissues of Norway spruce and preference of beetles for stressed trees.
Productivity and Seasonality Drive Total Soil Respiration in Semi-Arid Juniper Woodlands (Juniperus thurifera L., Southern Spain)
Authors: Morote Francisco Antonio García , Abellán Manuela Andrés , Rubio Eva , García Eduardo Martínez , Saucedo Francisco García , Córdoba Marta Isabel Picazo , Serrano Francisco Ramón López
Published: March 2022

We analyzed the relationship between forest productivity (joint effect of forest maturity and soil quality) and total soil respiration (µmol CO2 m−2 s−1) in semi-arid juniper woodlands (young woodlands growing in abandoned farmlands with deeper soils, and mature woodlands in lithic soils), and investigated the seasonal variation in soil CO2 efflux as a function of soil temperature and the soil water content. We measured the soil CO2 efflux from twelve cylinders in the soil over a three-year period using LI-6400 equipment. The results show that, in the more productive site (young woodland), soil CO2 efflux was higher due to greater respiration, mainly in the driest periods. Soil respiration followed a seasonal trend, being higher in spring and decreasing in cold periods. In both juniper woodlands and especially in the older forest, the CO2 efflux rates were low (<2.5 for Q10), typical of slow-growing species. Soil respiration was controlled by soil temperature without drought and in the temperate-warm season, whereas respiration showed sensitivity to soil water content in periods when edaphic humidity was low (but only in the more productive, young forest, which seemed to show better adaptation to drought), and under high soil moisture (soil water > 25%) for both woodlands, coinciding with warm temperatures in the spring. This period also corresponded to the highest CO2 efflux recorded in both woodlands. The accumulation of organic C seems to also be important to maintain elevated soil respiration in summer, especially in young woodlands. Thus, apart from microclimatic conditions, factors related to productivity regulate respiratory activity.
Cost Analysis of Seed Conservation of Commercial Pine Species Vulnerable to Climate Change in Mexico
Authors: Rodríguez-Zúñiga Joel , Flores-Ortiz Cesar M. , González-Guillén Manuel de Jesús , Lira-Saade Rafael , Rodríguez-Arévalo Norma I. , Dávila-Aranda Patricia D. , Ulian Tiziana
Published: March 2022

Mexico is home to 40% of the pine species in the world. By the year 2050, 20% of the Mexican forests could be lost because of climate change and other human-related activities. In this paper, we determine the potential areas for seed collecting of four species of the genus Pinus and its ex situ economic value under different future Climate Change Scenarios (CCS). The species analyzed were Pinus oocarpa Schiede ex Schltdl, P. rudis Endl., P. culminícola Andresen et Beaman and P. leiophylla Schiede ex Schltdl. and Cham which together accounts for 19% of the timber production in Mexico. Potential areas of distribution of populations in habitats with Annual Mean Maximum Temperatures (AMMT) for seed collection were modelled through a Geographic Information System and climate database. The seed storage economic value was determined by using the Collection Cost Method. The AMMT of P. oocarpa, P. rudis, P. culminícola and P. leiophylla were 28 °C, 20 °C, 18.3 °C and 27.4 °C, respectively. The economic losses from shortages of these species due to CCS in 2050, were estimated of 88.5 million (USD) and 67.16 million (USD) with severe and conservative future CCS, respectively. The nominal investment rate would be 8.84% or more, for storing seeds of the four species and withstanding climate change. An ex situ seed bank is a medium and long-term investment; among its benefits are establishing a market price for the use and conservation of species in the face of possible adverse scenarios.
A Monte Carlo Approach to Bitcoin Price Prediction with Fractional Ornstein–Uhlenbeck Lévy Process
Authors: Mba Jules Clément , Mwambi Sutene Mwambetania , Pindza Edson
Published: March 2022

Since its inception in 2009, Bitcoin has increasingly gained main stream attention from the general population to institutional investors. Several models, from GARCH type to jump-diffusion type, have been developed to dynamically capture the price movement of this highly volatile asset. While fitting the Gaussian and the Generalized Hyperbolic and the Normal Inverse Gaussian (NIG) distributions to log-returns of Bitcoin, NIG distribution appears to provide the best fit. The time-varying Hurst parameter for Bitcoin price reveals periods of randomness and mean-reverting type of behaviour, motivating the study in this paper through fractional Ornstein–Uhlenbeck driven by a Normal Inverse Gaussian Lévy process. Features such as long-range memory are jump diffusion processes that are well captured with this model. The results present a 95% prediction for the price of Bitcoin for some specific dates. This study contributes to the literature of Bitcoin price forecasts that are useful for Bitcoin options traders.
A Non-Signalized Junction Model for Agent-Based Simulations of Car–Pedestrian Mode Mass Evacuations
Authors: Lalith Maddegedara , Petprakob Wasuwat , Hori Muneo , Ichimura Tsuyoshi , Fujita Kohei
Published: March 2022

During major disasters, such as a subduction earthquake and the associated tsunami, combinations of uncommon conditions such as non-functioning traffic signals, a large number of pedestrians on traffic lanes, and debris scattered on roads can be widespread. It is vital to take these uncommon conditions into account since they can significantly influence the evacuation progress. Agent-Based Models (ABMs) with capabilities to reproduce evacuees’ behaviors as emergent phenomena is promising method to simulate combinations of such rare conditions. This paper presents a new model to cover the current research gap in accurately modeling car–car and car–pedestrian interactions at non-signalized junctions. Specifically, the details of accurately approximating car trajectories at junctions and automated construction, approximating free-flow speed of cars along curved trajectories, and accurately calculating the points of collision and time to collision are presented. As a demonstrative application, we simulated a hypothetical evacuation scenario with non-functioning traffic signals in which different numbers of slow evacuees are allowed to use cars. While the ABM is yet to be thoroughly validated, the presented demonstrative scenarios indicates that a considerable number of the needy can be allowed to use cars for evacuation if their routes and evacuation start time window are well planned.
Traumatic Tonsillar Hemorrhage during Hemophilia A Treatment with Emicizumab
Authors: Inoue Fumiya , Terada Kazuki , Furudate Kazuki , Noguchi Yasushi , Igarashi Shunji
Published: March 2022

Reports on the treatment of bleeding associated with emicizumab administration are scarce. Herein, we report the case of an eight-year-old boy with moderate hemophilia A with an inhibitor who experienced tonsillar hemorrhage while undergoing emicizumab treatment. He visited our hospital for postprandial bloody vomiting. The activated partial thromboplastin time was 20.8 s; only a small amount of hemorrhage was observed in the retropharyngeal space, and tranexamic acid was administered. He experienced hematemesis on Day 2 of hospitalization, and fiberoptic laryngoscopy confirmed hemorrhage from the posterior tonsil. Varicose vessels were observed at the soft palate, and considering thrombosis, an emergency cauterization was performed instead of bypass therapy. In small children, observing the tonsils is difficult, and the coagulation ability of the patient with hemophilia A is inferior to that of healthy people, even under emicizumab administration. Thus, active hemorrhage assessment and appropriate hemostatic control are necessary.
Train Strategies for Haptic and 3D Simulators to Improve the Learning Process in Dentistry Students
Authors: Coro-Montanet Gleyvis , Pardo Monedero María Jesús , Sánchez Ituarte Julia , de la Hoz Calvo Ana
Published: March 2022

Dental training faces the growing shortage of extracted teeth and the ethical precepts of Bionot learning on patients and reducing the environmental damage that preclinical trainings generate. Haptic and 3D simulators reproduce pathologies and provide a greater magnification of the processes, reducing water expenditure and pollution, but their curricular integration is complex. Two resources of complementary use (informative written manual and video tutorial) were designed to facilitate the theoretical and technical domain (know how the simulator works and make it work), as well as the advanced management of the simulator (operate the simulator autonomously, without setbacks). After 5 years of using these resources, an evaluative study was conducted with 175 students and 32 teachers. The aim was to assess the student’s perception of knowledge/learning, its statistical relationship with the didactic resources used and compare these results with the teachers’ perception of their students’ knowledge/learning. Spearman’s Rho coefficient and Kolmogorov-Smirnov test were performed. Both students and teachers considered that the technical domain (make the simulator work) was the domain that prevailed the most. There was a tendency for students not to value much the necessity of a specific preparation prior to using the simulator. This tendency resulted in a low level of study of both the written manual and the video tutorial. In conclusion, both students and teachers considered that the best strategy of knowledge/learning was the direct exchange with the simulator.
Social Norms and Family Child Labor: A Systematic Literature Review
Authors: Abdullah Alhassan , Huynh Inès , Emery Clifton R. , Jordan Lucy P.
Published: March 2022

Background. Research has established the family as the predominant context for child labor practices. Decisions to involve children in child labor within the family or by a family member (herein family child labor) is strongly motivated by cultural beliefs that normalize child labor. This systematic review sought to synthesize evidence on the social norms that support child labor practices, and the normative interpretation of international child labor legislation/standards. Methods. We followed the PRISMA procedure for systematic review by reviewing empirical articles published between 2000 to 2021 and contained within the four key databases: Scopus, ISI Web of Sciences, PubMed and Embase. Findings from 13 articles that met the inclusion criteria were analyzed thematically. Results. The review included studies from three continents: Africa, Asia and Europe. Gender norms, informal apprenticeship norm, norms on succession and sustenance as well as obedience, were key social norms that influenced child labor practices in the family. Parents’ decision to involve children in child labor was strongly influenced by the collective acceptance of some occupations (e.g., cocoa farming and fishing) as family occupations, which need to be preserved, undertaken and passed on to children. Child rights and the UNCRC principle of children’s participation were considered foreign to most non-western countries and interpreted as contravention to the cherished social norm of obedience. The findings underlie the link between social norms and the common social values of resilience, hard work, and respect. Conclusion. The results provide foundations and target to develop normative change intervention programs to re-orient the negative interpretations of common social values and provide alternative pathways that prevent child labor within the social context.
Relationship between Cigarette Smoking and Cancer Characteristics and Survival among Breast Cancer Patients
Authors: Darmon Sarah , Park Amie , Lovejoy Leann A. , Shriver Craig D. , Zhu Kangmin , Ellsworth Rachel E.
Published: March 2022

Carcinogenic effects of tobacco smoke may affect breast tumorigenesis. To assess whether cigarette smoking is associated with breast cancer characteristics, we investigated the relationships between smoking, pathological characteristics, and outcomes in 2153 women diagnosed with breast cancer 2001–2016. Patients were classified as never, former, or current smokers at the time of diagnosis. Logistic regression and multivariable Cox proportional hazards analysis were performed to determine whether smoking was associated with tumor characteristics. Multivariable Cox proportional hazards analysis was conducted to compare former or current smokers to never smokers in survival with adjustment for the potential confounders. The majority of women (61.8%) never smoked, followed by former smokers (26.2%) and current smokers (12.0%). After adjustment for demographic variables, body mass index, and comorbidities, tumor characteristics were not significantly associated with smoking status or pack-years smoked. Ten-year overall survival was significantly lower for former and current smokers compared to never smokers (p = 0.0105). However, breast cancer specific survival did not differ significantly between groups (p = 0.1606). Although cigarette smoking did not alter the underlying biology of breast tumors or breast cancer-specific survival, overall survival was significantly worse in smokers, highlighting the importance of smoking cessation in the recently diagnosed breast cancer patient.
Ecotoxicological Estimation of 4-Cumylphenol, 4-t-Octylphenol, Nonylphenol, and Volatile Leachate Phenol Degradation by the Microscopic Fungus Umbelopsis isabellina Using a Battery of Biotests
Authors: Janicki Tomasz , Długoński Andrzej , Felczak Aleksandra , Długoński Jerzy , Krupiński Mariusz
Published: March 2022

The phenolic xenobiotics nonylphenol (NP), 4-tert-octylphenol (4-t-OP), and 4-cumylphenol (4-CP) have the potential to seriously disrupt the endocrine system. Volatile phenols (VPs), especially those present in landfill leachate, also adversely affect the health of numerous organisms. Microbial degradation of xenobiotics can result in the formation of intermediates with higher toxicity than the precursor substrates. Therefore, the main aim of this study was to assess the changes in environmental ecotoxicity during the biotransformation of nonylphenol, 4-tert-octylphenol, 4-cumylphenol and volatile phenols by Umbelopsis isabellina using a battery of biotests. The application of bioindicators belonging to different taxonomic groups and diverse trophic levels (producers, consumers, and reducers) indicated a significant reduction in toxicity during the cultivation of fungus cultures both for nonylphenol, 4-tert-octylphenol, 4-cumylphenol and volatile phenols. The rate of toxicity decline was correlated with the degree of xenobiotic biotransformation. Removal of 4-cumylphenol and 4-tert-octylphenol also led to a decrease in the anti-androgenic potential. Moreover, this is the first report demonstrating the anti-androgenic properties of 4-cumylphenol. The results showed that U. isabellina is an attractive tool for the bioremediation and detoxification of contaminated environments.
Standardising Training of Nurses in an Evidence-Based Psychosocial Intervention for Perinatal Depression: Randomized Trial of Electronic vs. Face-to-Face Training in China
Authors: Nisar Anum , Yin Juan , Nan Yiping , Luo Huanyuan , Han Dongfang , Yang Lei , Li Jiaying , Wang Duolao , Rahman Atif , Li Xiaomei
Published: March 2022

Background: Rates of perinatal depression in China are high. The Thinking Healthy Programme is a WHO-endorsed, evidence-based psychosocial intervention for perinatal depression, requiring five days of face-to-face training by a specialist trainer. Given the paucity of specialist trainers and logistical challenges, standardized training of large numbers of nurses is a major challenge for scaling up. We developed an electronic training programme (e-training) which eliminates the need for specialist-led, face-to-face training. The aim of this study was to evaluate the effectiveness of the e-training compared to conventional face-to-face training in nursing students. Methods: A single blind, non-inferiority, randomized controlled trial was conducted. One hundred nursing students from two nursing schools were randomly assigned to either e-training or conventional face-to-face training. Results: E-training was not inferior to specialist-led face-to-face training immediately post-training [mean ENhancing Assessment of Common Therapeutic factors (ENACT) score (M) 45.73, standard deviation (SD) 4.03 vs. M 47.08, SD 4.53; mean difference (MD) −1.35, 95% CI; (−3.17, 0.46), p = 0.14]. There was no difference in ENACT scores at three months [M = 42.16, SD 4.85 vs. M = 42.65, SD 4.65; MD = −0.481, 95% CI; (−2.35, 1.39), p = 0.61]. Conclusions: E-training is a promising tool with comparative effectiveness to specialist-led face-to-face training. E-training can be used for training of non-specialists for evidence-based psychosocial interventions at scale and utilized where there is a shortage of specialist trainers, but practice under supervision is necessary to maintain competence. However, continued practice under supervision may be necessary to maintain competence.
Identification and Evaluation of Tools Utilised for Measuring Food Provision in Childcare Centres and Primary Schools: A Systematic Review
Authors: Elford Audrey , Gwee Cherice , Veal Maliney , Jani Rati , Sambell Ros , Kashef Shabnam , Love Penelope
Published: March 2022

Background: Children aged 2–11 years spend significant hours per week in early childhood education and care (ECEC) and primary schools. Whilst considered important environments to influence children’s food intake, there is heterogeneity in the tools utilised to assess food provision in these settings. This systematic review aimed to identify and evaluate tools used to measure food provision in ECEC and primary schools. Methods: The Preferred Reporting Items for Systematic Reviews (PRISMA) was followed. Publications (2003–2020) that implemented, validated, or developed measurement tools to assess food provision within ECEC or primary schools were included. Two reviewers extracted and evaluated studies, cross checked by a third reviewer and verified by all authors. The Academy of Nutrition and Dietetics Quality Criteria Checklist (QCC) was used to critically appraise each study. Results: Eighty-two studies were included in the review. Seven measurement tools were identified, namely, Menu review; Observation; Weighed food protocol; Questionnaire/survey; Digital photography; Quick menu audit; and Web-based menu assessment. An evidence-based evaluation was conducted for each tool. Conclusions: The weighed food protocol was found to be the most popular and accurate measurement tool to assess individual-level intake. Future research is recommended to develop and validate a tool to assess service-level food provision.
Proposal for Handling of Medicine Shortages Based on a Comparison of Retrospective Risk Analysis
Authors: Turbucz Bela , Major Martin , Zelko Romana , Hanko Balazs
Published: March 2022

Introduction: We reviewed and compared current drug shortages and shortage management practices in six selected countries (Hungary, Belgium, Spain, Switzerland, Australia, United States) based on the most comprehensive national shortage databases for each country, for four Anatomical Therapeutic Chemical (ATC) groups, to analyze the criticality of drug shortages across countries and identify best practices in shortage management strategies. Materials and Methods: Countries were selected to cover a wide geographical range of high-income nations where a lack of economic power as a potential source of drug shortages is not observable. ATC groups were selected based on a pre-examination of the databases to analyze groups most often in shortage, and groups where the absence of which could have a severe negative impact on treatment outcomes. The bias originating from the different reporting systems had to be reduced to gain comprehensive and comparable information. The first bias-reducing mechanism was transforming the raw number of shortages into proportion per million people. Secondly, critical cases were classified, and thirdly, critical cases were compared with the Word Health Organization (WHO) Essential Medicine Lists. Results: The results indicate that every European country studied reports significantly higher total and critical shortages per population compared to the US and Australia. Within Europe, Hungary reports the highest number of cases both for total and critical shortages, while Spain has the lowest results in both aspects. While in the US and Australia critical shortages were observable in similar proportions across all ATC groups, in European countries ATC groups of anti-infectives for systemic use (J) and the nervous system (N) were found to account for a notably higher proportion of critical shortages. Current shortage management practices were examined in each country and classified into five groups to identify common best practices. Conclusions: Due to the different characterization of reporting systems, several bias-reducing mechanisms should be applied to compare and evaluate shortages. In addition, European harmonization should be initiated to create mutually acknowledged definitions and reporting systems, which could be the basis of good drug shortage handling practices in Europe.
Openness to Experience Moderates the Association of Warmth Profiles and Subjective Well-Being in Left-Behind and Non-Left-Behind Youth
Authors: Ma Yongfeng , Ma Chunhua , Lan Xiaoyu
Published: March 2022

Crouched in the socioecological framework, the present research compared the subjective well-being of left-behind youth with their non-left-behind peers. Furthermore, this research investigated the association of parental warmth and teacher warmth using a person-centered approach with adolescents’ subjective well-being on the whole sample, and examined its conditional processes by ascertaining the moderating role of openness to experience and left-behind status in this association. A total of 246 left-behind youth (53.6% girls; Mage = 15.77; SD = 1.50) and 492 socio-demographically matched, non-left-behind peers (55.1% girls; Mage = 15.91; SD = 1.43) was involved in this study. During school hours, these adolescents were uniformly instructed to complete a set of self-report questionnaires. The results from ANCOVA exhibited no significant differences in subjective well-being between these two groups of youth. Moreover, four warmth profiles were revealed: congruent low, congruent highest, congruent lowest, and incongruent moderate, and youth within the congruent highest profile were more likely than the other three profiles to report higher subjective well-being. Additionally, moderation analyses demonstrated that high openness was one protective factor for subjective well-being, when left-behind youth perceived the lowest levels of parental warmth and teacher warmth congruently. These findings indicate that left-behind youth may not be psychologically disadvantaged in terms of positive psychosocial outcomes, such as subjective well-being, and school activities or social initiatives emphasizing openness to experience would be essential for them to facilitate positive adaptive patterns after parental migration.
Universal Health Coverage and the Pacific Islands: An Overview of Senior Leaders’ Discussions, Challenges, Priorities and Solutions, 2015–2020
Authors: Craig Adam T. , Beek Kristen , Gilbert Katherine , Soakai Taniela Sunia , Liaw Siaw-Teng , Hall John J.
Published: March 2022

In 1995, Pacific Health Ministers articulated their vision of a healthy Pacific as ‘a place where children are nurtured in body and mind; environments invite learning and leisure; people work and age with dignity; where ecological balance is a source of pride; and where the ocean is protected.’ Central to this vision is the achievement of universal health coverage (UHC). To provide an indication of the UHC-related priorities of Pacific health authorities and promote alignment of domestic and international investments in health sector development, we thematically analyzed the discussion, resolutions, and recommendations from 5 years (2015–2020) of senior-level Pacific health meetings. Five main themes emerged: (i) the Healthy Islands vision has (and continues to have) a unifying influence on action for UHC; (ii) adoption of appropriate service delivery models that support integrated primary health care at the community level are needed; (iii) human resources for health are critical if efforts to achieve UHC are to be successful; (iv) access to reliable health information is core to health sector improvement; and (v) while not a panacea for all challenges, digital health offers many opportunities. Small and isolated populations, chronic workforce limitations, weak governance arrangements, ageing and inadequate health facilities, and supply chain and logistics difficulties (among other issues) interact to challenge primary health care delivery across the Pacific Islands. We found evidence that the Healthy Islands vision is a tool that garners support for UHC; however, to realize the vision, a realistic understanding of needed political, human resource, and economic investments is required. The significant disruptive effect of COVID-19 and the uncertainty it brings for implementation of the medium- to long-term health development agenda raises concern that progress may stagnate or retreat.
The Management of Safety Situations and Assumable Risk during Transitions and Recesses in Different Types of Schools
Authors: Flores Òscar , Ramos-Pla Anabel , del Arco Isabel
Published: March 2022

The present study aims to analyze the situations of safety and risk perceived during the school transitions and recesses at different types of schools and to determine the level of empowerment of the students to manage situations of risk. The novelty of the study lies in analyzing the best strategy for dealing with risk situations during school transitions and recess. For this purpose, different situations in different types of schools are analyzed. An observational methodology was utilized. The sample was composed of a total of 23 schools, with 69 different observations conducted at different times of the day (morning recess and noon recess, on sunny days and rainy days). The results show that the morning recesses were the safest, and that the schools that serve a great number of at-risk students offered the greatest safety during recess and its transitions. With respect to the level of empowerment of the students, it was observed that they managed the possible risks when the safety guidelines were clear. The study provides evidence showing that when students are clearly aware of recess rules and guidelines, the management of risk situations improves.
ABA Mediates Plant Development and Abiotic Stress via Alternative Splicing
Authors: Yang Xue , Jia Zichang , Pu Qiong , Tian Yuan , Zhu Fuyuan , Liu Yinggao
Published: March 2022

Alternative splicing (AS) exists in eukaryotes to increase the complexity and adaptability of systems under biophysiological conditions by increasing transcriptional and protein diversity. As a classic hormone, abscisic acid (ABA) can effectively control plant growth, improve stress resistance, and promote dormancy. At the transcriptional level, ABA helps plants respond to the outside world by regulating transcription factors through signal transduction pathways to regulate gene expression. However, at the post-transcriptional level, the mechanism by which ABA can regulate plant biological processes by mediating alternative splicing is not well understood. Therefore, this paper briefly introduces the mechanism of ABA-induced alternative splicing and the role of ABA mediating AS in plant response to the environment and its own growth.