bluuebunny/crossref_metadata_2025 huggingface dataset:
Mieszkaniec, czyli kto? Próba oszacowania liczby ludności w województwie pomorskim w 2019 roku na podstawie danych BIG DATA użytkowników telefonii komórkowej
Authors: Przeworska Justyna , Turzyński Marcin
Published: January 2024

W artykule została omówiona metoda, która dzięki uzyskaniu danych big data z telefonii komórkowej umożliwiła podjęcie próby oszacowania różnicy pomiędzy bieżącą ewidencją ludności a rzeczywistą liczbą mieszkańców gmin województwa pomorskiego, ze szczególnym uwzględnieniem Trójmiasta wraz z jego bezpośrednim otoczeniem. Celem badania było określenie faktycznej liczby osób przebywających na obszarach gmin pomorskich. Uzyskane informacje w konfrontacji z danymi konwencjonalnymi ujawniły niedoszacowanie lub przeszacowanie liczby mieszkańców w gminach, pozwoliły uściślić liczbę turystów, użytkowników i odwiedzających, a także prześledzić przepływy ludności. Wyniki badania pokazały, że pojęcie mieszkańca jest coraz mniej jednoznaczne. Liczba osób uważanych za mieszkańców danej gminy, według przyjętej metody, nie jest stała w ciągu roku kalendarzowego i może być uwarunkowana sezonowo.
Συνηθισμένοι Άνθρωποι
Authors: Μούσουρα Διονυσία
Published: January 2024

Το βιβλίο Συνηθισμένοι Άνθρωποι, αποτελείται από 24 ιστορίες ανθρώπων της διπλανής πόρτας, βασισμένες σε πραγματικά γεγονότα και πρόσωπα από την ελληνική διασπορά. Όπου νέοι άνθρωποι, σχεδόν παιδιά, σπρωγμένοι από τη φτώχεια, την ανέχεια και την κατάσταση σε μια Ελλάδα ρημαγμένη από τον Β΄ΠΠ και τον Εμφύλιο τις δεκαετίες του -50 και του -60, αναγκάστηκαν να πάρουν τον, άγνωστο, δρόμο του ξενιτεμού. Σε όλες τις ιστορίες, λίγο-πολύ, κυριαρχεί ο πόνος του χωρισμού από τη γενέθλια γη και όλους τους αγαπημένους, ο φόβος για το άγνωστο, μα και η απελπισία, ότι δε θα δουν ξανά τη μάνα, τον πατέρα, τα αδέλφια. Η ανασφάλεια, για το τι θα βρουν στον ξένο τόπο, η τρομερή απόσταση και η σκέψη, πως δεν υπάρχει γυρισμός. Το σαράκι της νοσταλγίας που «ροκανίζει» τα σωθικά τους. Οι συνθήκες διαβίωσης αλλά και ο ρατσισμός, ιδίως τα πρώτα χρόνια. Κάποιες φορές, αμφιβολία και μεταμέλεια, αν η απόφαση ήταν σωστή και γιατί να την πάρουν. Μεγαλύτερος εχθρός του ξενιτεμένου η μοναξιά. Αλλά και η άγνοια της γλώσσας. Νέες κοπέλες και παιδιά, παντρεύτηκαν μόνα τους, οι κοπέλες γέννησαν τα παιδιά τους, χωρίς τη μάνα δίπλα τους. Η μεγάλη απώλεια για τα παιδιά τους, που δε γνώρισαν, γιαγιά, παππού, ξαδέλφια. Το Στερνό Αντίο, που δεν αξιώθηκαν να πουν. Οι περισσότεροι, έμαθαν το θάνατο του πατέρα ή της μάνας, όταν έφτανε το γράμμα 4 και 6 βδομάδες αργότερα. Πολλές φορές, διαπιστώνοντας, με απόγνωση, πως όταν τους κήδευαν, εκείνοι, λόγω άγνοιας, βρίσκονταν σε γλέντι! Δεν υπάρχει αρχή και τέλος να εκφραστούν τα συναισθήματα των ανθρώπων της μετανάστευσης. Χειρότερο από όλα, η οδύνη, στην έστω και προσωρινή τους επιστροφή στην πατρίδα, πως δεν ανήκουν πια εκεί. Ξένοι στην ξένη γη, ξένοι και στον τόπο τους, που κρατούσαν φυλαχτό ιερό στην καρδιά, όλα αυτά τα χρόνια.
Snapshot of International Radıotherapy Center: Single Center Experience
Authors: Uysal Bora
Published: January 2024

Cancer can become anywhere in the human body almost including trillions of cells. Cancerous tumors spread or invade into the tissues to form new tumors that named as the process of metastasis. Radiation therapy (RT) was first used to treat cancer over a hundred years ago. The progress has been made to improve the effectiveness of this awesome modality and minimize side effects. RT also has been used with surgery, chemotherapy or immunotherapy in combined modality approaches for numerous malignancies to maximize tumor control while minimizing toxicity and preserving the organs and tissues. We intend to present our patient population whom delivering radiotherapy in our radiotherapy center. The data includes the patients who still delivering radiotherapy, initial or last day of radiotherapy. This article is about a snapshot of a treated patient population in one day at our center. Mean KPS (Karnofsky Performance Score) was 90 (70-100). 2 patients were in stage 1 (2%), 25 (28%) were in stage 2, 35 (39%) wee in stage 3 and remaining 23 (26%) were in stage 4. 4 (5%) of all were benign.
The Richness of the Medicinal Plants 0f Turkey
Authors: Koroglu Aysegul
Published: January 2024

In this review, the reasons for plant richness in Turkey are given compiled. In addition, the phytogeographic and geopolitical structure of Turkey and its impact on medical plants have been examined. In the light of this information; the current situation has been evaluated.
Skipping Breakfast Everyday Keeps Well-Being Away
Authors: Mohiuddin AK
Published: January 2024

Breakfast, the first meal of the day, is considered the most important meal throughout the day. As nutritionist Adelle Davis famously put it back in the 1960s: “Eat breakfast like a king, lunch like a prince and dinner like a pauper”. Breakfast is most commonly skipped meal more than lunch and dinner specifically in the young adult in the university study period and those who wake up late. Lack of time is the main reason behind skipping meals, in general, lack of appetite, inability to cook, fasting/religion, and not being hungry. Many people are used to be in a hurry for job, business, children’s’ school in the morning where a filled stomach may prevent them to walk a long way. It is obvious that the irregular omission of breakfast may be effective in energy intake reduction over the next 24 hours and in this day, exercise performance may be compromised. There is no evidence that breakfast skipping reduces overeating or prevent weight gain. Some people argue that breakfast and good health is a marketing strategy by breakfast companies.
Physician – First Do No Harm
Authors: Lader Malcolm
Published: January 2024

I draw attention to the repeated and apparently unending dependence and abuse problems associated with a series of psychotropic medications including the barbiturates, benzodiazepines and opioids.
Molecular Pharmacology: Search for New Target-Drug in Neoplasia’s
Authors: Soeiro Pantoja Wendell Mauro
Published: January 2024

Neoplastic diseases are the second cause of death and according to annual statistics. Malignant brain tumors and head and neck cancer, including mouth cancer are the most common, and although they have a low incidence, have a high mortality rate. Currently, 90% of chemotherapy failures occur during invasion and metastasis of tumors related to drug resistance. Administration of a given drug, even in therapeutic amounts, leads to many tumor cells from patients becoming resistant to the drug. Thus, drug resistance appears as a serious problem in the field of cancer, since there are several mechanisms of avoidance.
sotopic Abundance Ratio Evaluation of the Consciousness Energy Treated Pyridoxine Using LC-MS and GC-MS Spectrometry
Authors: Jana Snehasis
Published: January 2024

Vitamin B6 (pyridoxine) has an important role in physiologic development. In this study, the influence of the Trivedi Effect®- Consciousness Energy Treatment on the structural properties and the isotopic abundance ratio of pyridoxine were evaluated using LC-MS and GC-MS analytical techniques. The test sample pyridoxine was divided into Control / untreated and the Biofield Energy Treated sample. The treated pyridoxine sample received Biofield Energy Treatment (the Trivedi Effect®) remotely for ~3 minutes by Mr. Mahendra Kumar Trivedi, who was in the USA, while the test samples were in the research laboratory in India. The LC-MS spectra of both the samples at retention time ~2.33 minutes exhibited the mass of the protonated molecular ion peak [M+H] + at m/z 170 in the MS spectrum. The isotopic abundance ratio of PM+1/PM in the treated pyridoxine was significantly increased by 14.44% compared with the control sample. Thus, 13C, 2H, 15N, and 17O contributions from (C8H12NO3) + to m/z 171 in the treated sample were significantly increased compared with the control sample. Similarly, in the GC-MS chromatograms, the peak area of the treated sample was significantly increased by 100.63% compared to the control sample. Similarly, the mass peak intensity of the treated pyridoxine at m/z 153 was increased by 1.1% compared to the control sample. The isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O) and peak area in the treated pyridoxine was significantly increased compared to the control sample. The decreased isotopic abundance ratio of the treated pyridoxine may increase the intra-atomic bond strength, increase its physical stability. The increased peak area of the treated pyridoxine might be responsible for the increase in solubility and bioavailability compared to the control sample. The new form of pyridoxine would be better for designing more efficacious nutraceutical formulations for the prevention and treatment of pyridoxine deficiency, anemia, seizures, cardiovascular disease, tuberculosis, Alzheimer’s disease, cancer, anxiety, hypertension, asthma, depression, dysmenorrhea, breast pain, etc.
Effect of Biofield Treatment on Blood, Hepatic, and Cardiac Biomarkers in Vitamin D3 Deficiency Diet (VDD) Induced Sprague Dawley Rats
Authors: Jana Snehasis
Published: January 2024

A novel proprietary formulation was designed that consist of minerals (magnesium, zinc, copper, calcium, selenium, and iron), vitamins (ascorbic acid, pyridoxine HCl, alpha tocopherol, cyanocobalamin, and cholecalciferol), Panax ginseng extract, β-carotene, and cannabidiol isolate. The study objective was to evaluate the impact of Consciousness Energy Healing Treatment (the Trivedi Effect®) on a novel test formulation in male Sprague Dawley (SD) rats, fed with vitamin D3 deficiency diet (VDD) for immunomodulatory activity. The test formulation was divided into two parts. One part was denoted as the untreated test formulation without any Biofield Energy Treatment, while the other part was defined as the Biofield Energy Treated sample, which received the Biofield Energy Healing Treatment by renowned Biofield Energy Healer, Mr. Mahendra Kumar Trivedi. The level of total leukocytes count (TLC) were significantly increased by 23.1% and 17.44% in the Biofield Energy Treated test formulation (G5) and Biofield Energy Treated test formulation from day -15 (G7) groups, respectively compared with the disease control group (G2) induced by VDD. Moreover, the level of neutrophils was significantly increased by 71.68%, 92.92% (p≤0.01), 42.48%, and 49.56% in the G5, G7, Biofield Energy Treatment per se plus Biofield Energy Treated test formulation from day -15 (G8), and Biofield Energy Treatment per se animals plus untreated test formulation (G9) groups, respectively compared with the G2 group. Monocyte level was also increased by 23.53%, 17.65%, and 29.41% in the G5, Biofield Energy Treatment per se to animals from day -15 (G6), and G9 groups, respectively compared to the G2 group. Hepatic biomarker like alkaline phosphatase (ALP) was significantly reduced by 14.98% and 23.07% (p≤0.05) in the G7 and G9 groups, respectively as compared to the G2 group. Besides, cardiac biomarker like creatine kinase myocardium band (CK-MB) was also significantly (p≤0.05) reduced by 20.99% in the G6 group compared with the G2. Altogether, results suggested that the Biofield Treated test formulation and Biofield Energy Treatment per se significantly increased immune-related parameters, which might be beneficial for the management of immune-compromised patients as well as to boost-up the immunity in healthy peoples. The results showed a significant slowdown of disease progression and all other disease-related complications/symptoms in the preventive Biofield Energy Treatment group per se and the Biofield Energy Treated Test formulation groups (viz. G6, G7, G8, and G9) as compared to the disease control group.
Retrospective Review of 45 Implanted Human Acellular Dermal Lyophilized Implants to Stabilize Talotarsal Instability, Single Center, Single Surgeon Case Series
Authors: Werber Bruce
Published: January 2024

A retrospective review of 45 surgeries for repair of Talotarsal instability, with a review of the clinical, radiographic, and biomechanical aspects associated with Talotarsal dislocation and instability. The surgeons utilized an acellular lyophilized human dermal tissue engineered into a cylindrical configuration (stent) to be implanted from lateral to medial via the sinus tarsi. The goal of surgery is to reduce the dislocation, to enhance positioning of the rearfoot and allow regeneration of the Talotarsal ligamentous structures into a more stable configuration. Outcomes found in this review are very promising, none of the implant stents required removal, elimination of the sense of hard stop as seen with other materials in this procedure. Conclusion: excellent outcomes with minimal adverse events, rapid restoration of function in all patients.
Carpo-Metacarpal Joint Dislocation of the Thumb-Conservative Treatment
Authors: Jouni Haidar
Published: January 2024

Introduction: Isolated thumb carpometacarpal joint dislocation is a rare lesion that accounts for less than 1% of all hand injures. We present traumatic isolated thumb carpometacarpal joint dislocation case. Patient treated conservative by closed treatment under local anesthesia, he had a good functional outcome and showed no signs of thumb carpometacarpal instability or arthritis. Isolated thumb carpometacarpal dislocation is a rare lesion that can cause joint instability or arthritis, which interferes with the normal function of the hand and can lead to articular degenerative changes. The best management of this lesion is still controversial, since there is lack of evidence in the literature showing superiority of one treatment over the other.
Analysis of Regeneration Tissue Formed in the Treatment of Cartilage Defects
Authors: Satana Tolgay
Published: January 2024

Joint function losses that occur as a result of injury, healing and scarring of the cartilage tissue are varied. In this study, the contralateral joints of rabbits with complete cartilage loss were defined as the control group. Self-healing of similar cartilage losses and popular surgical methods were compared, and the results were examined histopathologically. As a result, it was determined that while autogenous full-thickness osteochondral cartilage transfer resulted in the best cartilage healing, the healed cartilage tissue without any intervention was superior to methods such as drilling and carbon fiber. We concluded that cartilage tissue must be “no men land” if lower than full thickness cartilage lesions. Cartilage must be protected any surgical impact instead of main mechanical articular problems must be focused.
A Few Words about Ankle–Foot Amputations
Authors: Franjić Siniša
Published: January 2024

Amputation is cutting off a bone in healthy tissue or cutting off a part of the body at a joint. Such an amputation is necessary when the diseased part of the body is not expected to heal, and thus the patient’s life is in danger. Causes may include circulatory disorders, infections, accidents, cancer, or congenital malformations of the extremities. In these cases, the need for amputation is usually known in advance.
Vitamin D - The Essence of Survival
Authors: TH Elidrissy Abdelwahab
Published: January 2024

Although there is no evidence of the role of Vitamin D in fertilization, we suggest this area and role of Vitamin D needs to be studied. During the forty weeks, the needs of the fetus to the means of survival through the placenta is maintained. As for calcium, trans-placental pump which is not Vitamin D dependent and is maintaining enough to build the bones and maintain the heart pumping, from the maternal circulating calcium. It is only in situations of severe symptomatic osteomalacia of the mother that cases of congenital rickets were reported. It is true that maternal osteomalacia causes fetal rickets which was reported at the beginning of the twentieth century from China. At birth, maternal Vitamin D deficiency can lead to failure of progress in labor that might increase the rate of Caesarian Section.
Clinical Study on Dashanga Guggulu and Surya Namaskar in the Management of Sthaulya (Obesity) In Children
Authors: Kumar Singhal Harish
Published: January 2024

Introduction: One of the oldest medicinal sciences in the world is Ayurveda. It describes the conceptual analysis of various diseases using its own principles and methodologies. Distinct Acharya has given different descriptions of “Sthoulya” in Ayurveda. In Ayurveda terms, Sthoulya is used as overweight and obesity. Obesity is defined as an overabundance of adipose tissue-fat depot in the body. This study has undertaken the management of Sthoulya by assessing the comparative efficacy of Dashanga Guggulu and Surya Namaskar in the management of Sthoulya (childhood obesity). The available data is based on clinical findings.
An Examination of Management Patterns and Perceived Health Status of Patients with Osteoporosis within Bayelsa State
Authors: Owonaro Peter A
Published: January 2024

Osteoporosis, characterized by diminished bone mass and microarchitectural bone tissue degradation leading to heightened bone fragility and susceptibility to fractures, is a condition that often goes underdiagnosed and undertreated. This cross-sectional survey aimed to assess medication management and the perceived health status among a diverse group of osteoporosis patients, spanning a wide age range (20-80 years), within the general population of Yenagoa, Bayelsa State. The data collection period for this study extended from March 2022 to May 2022, and information was gathered using a questionnaire specifically developed by the researchers. The study population predominantly consisted of females (55%), primarily aged above 40 years, with a substantial proportion possessing technical education (33%). Most participants were married (82%), employed, and exhibited modal body weights within the range of 60-70 kg (25%). A noteworthy portion had a history of vitamin D supplementation (60%), although daily steroid use was less prevalent (56%). While a majority reported adherence to their prescribed medication regimen (64%), they displayed limited awareness of the potential risks associated with non-adherence (64%). Many participants sought treatment for osteoporosis from multiple healthcare facilities. The daily management of the condition was mainly overseen by bone specialists (40%) and local practitioners (34%).
The Use of Autologous Tibia Strut Grafts to Enhance Bone Healing of an Infected Long-Bone Nonunion
Authors: Cristina Reynders-Frederix
Published: January 2024

We treated five patients with an infected non-union of the femur and tibia with autologous tibia strut grafts. All patients had bone defects ranging from three to nine centimeters. Three patients suffered for more than seven years from chronic osteitis. Our objective was to describe this grafting technique and its results. We focused on healing time, postoperative complications and functional recovery. We retrospectively studied five patients with an infected non-union of the lower limb who had undergone previous surgeries to overcome the bone healing problem. In this group of patients, we had four femur non-union and one tibia non-union. All of them had a previous infection episode, in which medical and surgical therapy was needed. Of the participants, three were men, and two were females with a mean age of 43.3 years (28-55).
Kajian Pustaka: Gambaran Klinik dan Penanganan Pankreatitis Akut pada Anjing
Authors: Juliantari Putu Teza , Heparandita Ananda Agung Dextra , Sosiawan I Gede Arya Mas , Sitohang Martina Tiodora , Batan I Wayan
Published: January 2024

Pankreatitis akut adalah kondisi inflamasi yang menimbulkan nyeri abdomen dan enzim pankreas diaktivasi secara prematur dan mengakibatkan autodigestif pankreas. Pankreatitis dapat bersifat akut atau kronis, dengan gejala ringan sampai berat. Dilakukan kajian pustaka dari artikel pankreatitis akut yang dilaporkan di seluruh dunia secara online melalui Google Scholar dan PubMed menggunakan kata kunci pencarian “Pancreatitis”, “Acute Pancreatitis”, “Radiograph”, “USG”, dan “CT-Scan”. Dari sembilan kasus yang dibandingkan, ditemukan kesamaan anamnesis, yaitu nyeri perut dan muntah. Hal ini disebabkan karena pankreatitis akut menimbulkan nyeri karena enzim pankreas diaktivasi secara prematur dan mengakibatkan pankreas mengalami autodigestif. Peneguhan diagnosis dilakukan dengan pemeriksaan hematologi, pemeriksaan radiografi, ultrasonografi (USG), ataupun dengan computerized tomography scan (CT-scan). Temuan yang muncul adalah area lobulasi jaringan hipoekoik yang abnormal pada lobus pankreas dengan pemeriksaan ultrasonografi serta peningkatan kadar lipase dan protein C-reaktif yang merupakan indikator yang bisa digunakan untuk mengetahui terjadinya pankreatitis akut. Penanganan dan pengobatan dilakukan dengan pemberian terapi cairan, obat anti muntah maropitant, antibiotik ampisilin, antibiotik metronidazol, obat asam lambung omeprazole, dan diet rendah lemak. Laparotomi dilakukan pada dua dari sembilan kasus guna meredakan nyeri pada abdomen. Gastrotomi dilakukan pada kasus enam, yaitu pada anjing betina ras Bull terrier berumur dua tahun akibat adanya benda asing (dua buah karet) pada bagian kardiak lambung. Jika anjing mengalami tanda-tanda klinis mengarah ke pankreatitis harap segera dibawa ke klinik hewan untuk diperiksa dan dilakukan pemeriksaan berupa pemeriksaan darah lengkap, biokimia serum, dan ulrasonografi agar diketahui apabila memang terjadi kasus pankreatitis akut dan bisa diberikan treatment lanjutan sehingga peluang anjing pulih dan selamat lebih besar.
Laporan Kasus: Penanganan Ehrlichiosis pada Anjing Akita dengan Pemberian Doksisiklin dan Transfusi Darah
Authors: Florensia Dheadora , Batan I Wayan , Soma I Gede
Published: January 2024

Ehrlichiosis merupakan penyakit pada anjing yang dapat menyerang semua umur dan ras. Ehrlichiosis disebabkan oleh Ehrlichia sp. yang merupakan bakteri obligat intraseluler Gram negatif dari genus Ehrlichia. Seekor anjing jantan ras Akita bernama Yama, warna rambut putih dan cokelat, berumur tujuh tahun, dan bobot badan 28 kg dibawa ke Anom Vet Clinic dengan keluhan lemas, nafsu makan menurun, dan mengalami epistaksis sebelum dibawa ke klinik. Hasil pemeriksaan klinis anjing kasus ditemukan kepucatan pada mukosa mulut dan konjungtiva, infestasi caplak Rhipicephalus sanguineus pada kulit dan anjing mengalami epistaksis bilateral. Hasil pemeriksaan hematologi rutin menunjukkan bahwa anjing kasus mengalami anemia mikrositik normokromik, trombositopenia, dan leukopenia. Hasil pemeriksaan test kit menunjukkan hasil positif mengandung antibodi E. canis. Berdasarkan anamnesis, tanda klinis, hasil pemeriksaan hematologi, dan pemeriksaan menggunakan test kit, maka anjing kasus didiagnosis menderita ehrlichiosis dengan prognosis dubius. Penanganan yang diberikan pada anjing kasus yaitu, dengan pemberian cairan Ringer Laktat 910 mL/hari, doksisiklin 5 mg/kg BB, BID, PO selama tujuh hari, transfusi darah sebanyak 337 mL, dan pemberian vitamin B kompleks satu tablet per hari selama 10 hari. Penanganan pada hewan kasus menunjukkan hasil yang baik secara klinis dengan epistaksis sudah tidak terlihat dan nafsu makan mulai membaik pada hari ketiga. Pada hari ke-10 kondisi anjing kasus membaik secara klinis dan diperbolehkan pulang.
Dispen-ku Android-Based Application: Assisting Religious Court Judges in Deciding for Marriage Dispensation
Authors: Zuhriah Erfaniah , Mayasari Lutfiana Dwi , Rahmawati Erik Sabti , Razak Abdul Qayuum Bin Abdul , Sukadi Imam
Published: January 2024

The high rate of child marriage in Indonesia following the marriage dispensation procedure demands an application to help judges decide the proposals accurately and effectively. This 4D development model research aims to create a standard reference in making decisions regarding the dispensation of marriage proposals using an application. The first stage is defining variables used at the application as measurement, the second stage is designing, namely the process of preparing a conceptual framework in the form of technological innovation, the third stage is developing technological innovation and the fourth stage is disseminating, namely the use of an application. At the defining stage, the variables to measure the level of urgency in granting the marriage dispensation include Social, Partnership Role,  Financial, Spiritual, and Reproductive or Sexual Readiness. At the designing stage, the Dispen-Ku application is created using Kodular, a website that provides tools for creating Android applications using block programming. In the disseminating stage, the Dispen-ku application which has been uploaded to the Playstore page is distributed to research subjects, namely two judges in Religious Courts.
Analysis of the influence of substitute fuels on properties operating conditions of military hybrid drive systems
Authors: Chojnowski Janusz
Published: January 2024

The energy density of chemical batteries makes it difficult to rely solely on cheap and eco-friendly electricity for power in many applications, such as airplanes, long-distance trains, ocean vessels, and heavy equipment. Limited charging infrastructure and power generation capacity are also problematic. However, hybrid powertrains provide a solution by combining electric and internal combustion engines to achieve better fuel economy and similar operational characteristics to traditional engines. Hybrid systems can also use alternative hydrocarbon fuels , with all advantages of conventional engines. This study aimed to determine the impact of alternative fuels on the performance of a hybrid drive system for a military wheeled platform developed for operation in urban areas. The experiment found that substitute fuels, such as, F-34, and Jet A-1, were compatible but could result in increased fuel consumption, decreased energy efficiency, and negative environmental impacts due to higher exhaust emissions.
Study of the effect of ignition crank angle and mixture composition on the performance of a spark-ignition engine fueled with ethanol
Authors: Jakliński Piotr , Czarnigowski Jacek , Ścisłowski Karol Jan
Published: January 2024

The publication presents the results of the measurements of the operating parameters of a spark-ignition engine fueled with 95-octane unleaded gasoline (ES95) and ethyl alcohol, approx. 92%. The measurements were carried out at a constant load: an engine speed of 1,500 rpm and a constant pressure in the intake system - MAP=0.45 bar. For each type of fuel, the measurements were carried out in two series for two variables. The ignition crank anglewas varied in the range of 0˚÷40˚ and the mixture composition λ in the range of 0.85÷1.25. The recorded engine performance parameters included torque, intake manifold pressure, intake air temperature, exhaust gas temperature and temporal fuel consumption; and exhaust gas composition was examined in terms of carbon monoxide, hydrocarbons and nitrogen oxides. The study showed that an ethanol-fueled engine has lower average efficiency compared to a gasoline one. The highest efficiency for ethanol was obtained for rich mixtures in the range λ=0.85÷1.0 and at high ignition advance angles. The use of alcohol fuel showed a very favorable effect on the composition of exhaust gas and a significantly lower content of harmful exhaust components was demonstrated. For the same operating points, carbon monoxide content was reduced by an average of 15%, and hydrocarbons and nitrogen oxides by an average of 80%.
Crosstalk between cancer cell plasticity and immune microenvironment in cholangiocarcinoma
Authors: Minini Mirko , Pavy Allan , Lekbaby Bouchra , Fouassier Laura
Published: January 2024

Cholangiocarcinoma (CCA) is a highly aggressive tumor of the biliary tree characterized by an intense desmoplastic tumor microenvironment (TME). To date, treatment of CCA remains challenging; tumor resection is the only curative treatment with a high recurrence probability. Besides resection, therapeutic options have moved forward with the advent of immunotherapies, but these remain limited and low effective. Our knowledge about the cellular interplays in CCA is still fragmentary. An area is currently emerging regarding the potential role of cancer cell plasticity in the genesis of an immunosuppressive microenvironment. The cancer cells’ ability to acquire stemness properties and to disseminate through an epithelial-mesenchymal transition (EMT) shape a tumor immune microenvironment that supports cancer progression by attracting immunosuppressive cells including myeloid-derived suppressor cells (MDSCs), regulatory T cells (Tregs), M2 macrophages, and by increasing the expression of inhibitory immune checkpoints such as PD-1/PD-L-1. EMT-inducing transcription factors (EMT-TF) have recently emerged as regulators of tumor immunity by creating an immunosuppressive microenvironment. This review delves into the molecular mechanisms underlying the existing links between EMT/stemness and tumor immune microenvironment, as well as the last discoveries in CCA.
Scandals in the Global Village
Authors: Burkhardt Steffen
Published: January 2024

The specific characteristics of political scandals in a global context follow the historical evolution of international communication technologies and media systems. This article examines the development of political scandals through selected cases in a global context. The global scandal evolution took place in three phases: (1) the written duplication of morals created the conditions for international reports on political scandals; (2) the establishment of an international media system transformed political scandals into an integral part of global public spheres; (3) the digitization of scandals on the Internet put moral pressure on global politics – resulting in permanent and omnipresent international scandal discourses. The digitization of political scandals comes, on the one hand, along with the loss of journalistic gatekeepers, post-truth manipulation of public spheres, influence from abroad and the risk of social unrest. On the other hand, it provides the chance to better understand the chances and limits of globalization.
Outrage, Solidarity,Counterattack
Authors: Dvorak Jan
Published: January 2024

The prevalence of politicians’ scandals on social media has become an integral part of contemporary political life, presenting a challenge to existing scandal research. The formerly passive audience is given new opportunities for participation that have not yet been comprehensively described either theoretically or empirically. This study contributes to filling this gap by developing a taxonomy to describe offensive and defensive forms of audience participation during scandals. I analyze a sample of 500 influential tweets, taken from a corpus of more than 55.000 tweets related to two scandalizations of German politicians. The proposed taxonomy is shown to be suitable for describing both offensive and defensive forms of audience participation in scandalizations on social media.
‘Accidental Celebrities’
Authors: Prémont Karine , Millette Alexandre
Published: January 2024

Using quantitative analysis, we analyzed the coverage of women indirectly involved in four major U.S. presidential scandals (Watergate, Iran-Contra, Clinton-Lewinsky affair, Ukraine quid pro quo) through 258 articles published in six magazines (The Atlantic, The New York Times Magazine, Time, The New Yorker, Newsweek, Rolling Stone) to assess how they are described by journalists. Three assumptions guided our analysis. First, women are covered in a negative way even if they are not responsible for the scandal. Second, they are covered by the magazines in a stereotypical way to describe their behavior, their character, or their role in the scandal. Finally, the coverage of women involved in more recent scandals is less stereotypical and less negative. While the literature shows that women receive more negative coverage than men when they are responsible for political scandals, our results show that this is also the case for these “accidental celebrities”.
Criminality of Prostitution Abuse
Authors: Kogovšek Šalamon Neža , Frelih Mojca , Učkar Tjaša
Published: January 2024

The article is based on an empirical socio-legal analysis of criminal court case ‎files concerning prostitution abuse in Slovenia. Based on the theoretical framework developed by Petra Östergren, the authors analyse whether the Slovenian ‎regulatory system on sex work is repressive, restrictive or integrative. The paper explores how the courts define “abuse” and “exploitation” of prostitution, ‎how the participation of third parties in sex work activities is dealt with by ‎the courts, how the vulnerability of sex workers is treated, and how the existence of consent is considered before the courts. The paper examines the files ‎for moral arguments, stereotyping, and stigmatisation, as well as references to ‎occupational risks in the field of sex work and sex workers’ rights. In the conclusions the authors argue that in Slovenia the characteristics of the restrictive ‎model, with elements of both repressive and integrative, prevail.
On improbable carrots
Authors: Todosijević Bojan , Pavlović Zoran
Published: January 2024

Membership in the EU is sometimes presented as a reward for Serbia’s eventual acknowledgement of Kosovo’s independence. Although membership in the EU has been a strategic goal of Serbian foreign policy, the EU is often perceived as working against Serbian national interests regarding Kosovo’s status. Relying on the cognitive dissonance theory, we hypothesize that in addition to a direct negative association between the support for Serbia’s territorial integrity and the EU membership, there is also an interactive effect: the association should be moderated by one’s opinion on when and whether Serbia will become a member of the EU. These hypotheses are examined using public opinion data based on a large national sample of adult Serbian citizens. The results support the interaction hypothesis: the attitude that Kosovo should remain part of Serbia is a stronger predictor of the (negative) evaluation of the EU among those respondents who do not believe that Serbia will become an EU member in the future.
Odnos identiteta i uloga u međunarodnim odnosima i spoljnoj politici
Authors: Kovačević Marko
Published: January 2024

Cilj ovog rada je da omogući temeljan uvid u ključne teorijske rasprave u vezi sa odnosom identiteta i uloga u disciplini međunarodnih odnosa i analizi spoljne politike, s posebnim fokusom na teorijske pristupe socijalnog konstruktivizma i teorije spoljnopolitičkih uloga. Imajući u vidu odsustvo interesovanja za ovaj pristup istraživanju u regionalnoj akademskoj literaturi, sistematizujem tri dimenzije proučavanja uloga u spoljnoj i bezbednosnoj politici: ontološku, epistemološku i metodološku. U ovom nastojanju da se prokrči put daljim istraživanjima, poseban naglasak se stavlja na uloge malih država u svetskoj politici između strukturnih imperativa i mogućnosti delatništva. Teorija uloga se sagledava u svom odnosu prema konsturktivističkoj analizi spoljne politike, pri čemu se ukazuje na osnovne pojmove teorije uloga, interpretativnu metodologiju i neke primere istraživanja diskurzivnog konstruisanja identiteta i uloga država. U zaključku se osvrćem na neka dalja pitanja i jednu istraživačku agendu identiteta i uloga u međunarodnim odnosima
Transformacija javnih politika u suvremenom kontekstu
Authors: Petek Ana
Published: January 2024

Cilj je ovoga rada pripremiti osnove za utemeljenu procjenu transformacije suvremenog stvaranja javnih politika pod utjecajem aktualnih kriza na način da se detektiraju dimenzije u kojima se promijenio kontekst stvaranja javnih politika krajem 20. i početkom 21. stoljeća. Rad je zasnovan na pregledu literature iz politološke discipline javnih politika, ali i srodnih disciplina javne uprave i socijalnih djelatnosti koje svojim specifičnim konceptima također pokušavaju razaznati transformaciju suvremenih javnih politika. Prvo se pokušavaju grubo sistematizirati osnovni elementi promjena konteksta u sklopu društva, tržišta i države, a zatim se fokusira na istraživanje tipova države s obzirom na fukcije koje ona ispoljava kroz raznorodne javne politike; na vrste javnog upravljanja i višestruke oblike kroz koje ono danas djeluje; te na transformaciju socijalne države u smjeru kombiniranih socijalnih politika. Glavni je nalaz rada da nove funkcije, nove strukture, novi ciljevi, novi instrumenti i novi akteri koje se može pronaći u stvaranju javnih politika na prijelazu stoljeća ne istiskuju stare, već se na njih nadograđuju i talože kao dodatni slojevi. Takozvano slojevanje čini se ključnom značajkom suvremenog stvaranja javnih politika, iako se još ne može odrediti hoće li ono olakšati ili onemogućavati rješavanje aktualnih kriza, te stoga treba biti središnji fokus interdisciplinarnih istraživanja društvenih znanosti u nadolazećem razdoblju.
Review of the Historic Trajectory of Deforestation, its Drivers and Implications in Ethiopia
Authors: Kassaye Mulugeta Lemenih
Published: January 2024

This paper aims to provide a comprehensive review of the historical trajectory of deforestation in Ethiopia, spanning an extensive timeframe and exploring its major driving factors. Over the span of three millennia, Ethiopia has experienced persistent deforestation, resulting in a significant reduction of its once-large forest and woodland resources. Currently, small, degraded forests and woodlands exist in isolated patches, located in remote areas such as the southwest and southeast. Major deforestation in Ethiopia unfolded progressively, first along a north-south axis and more recently shifting from the highlands to the lowlands. The northern and central highlands lost most of their natural forests before the turn of the 20th century, while significant loss in the southern highlands occurred over the past 150 years, and in the lowlands over the past 50 years. This deforestation is primarily attributed to the expansion of ox-plow agriculture and population pressure resulting from natural birth and internal migration. Despite efforts to counter deforestation and promote restoration, mostly since the 1970s, successes remain limited. A noteworthy exception in this regard is the introduction of Eucalyptus during the turn of the 20th century and the subsequent expansion of it, mainly in the form of small-scale farmer-led farm forestry. Today, Eucalyptus become the most preferred, well-adapted, widely planted, and the major supplier of wood materials in Ethiopia. The limited success in restoration is attributed to the reliance on campaign-based strategy, lack of private sector involvement, the intertwining of restoration with political agenda, and poorly defined property rights on land, forests, and trees. The consequences of deforestation and resultant environmental degradation have profoundly influenced the socio-economic dynamics of Ethiopia, giving rise to issues such as food insecurity, poverty, migration, and political instability.
Plasma mir-203a-3p as a Novel Diagnostic Biomarker in Patients with Parkinson’s Disease Dementia
Authors: Hsu Ya-Fang , Lin Shau-Ping , Chu Yung-Tsai , Tsai Yi-Tzang , Phoa Frederick Kin Hing , Wu Ruey-Meei
Published: January 2024

The early detection of cognitive decline and timely non-pharmacological management or drug therapy are extremely important in providing care for Parkinson’s disease with dementia (PDD). In this study, we first conducted a discovery study to identify six plasma microRNAs that may allow for the differentiation of PD with or without mild cognitive impairment via NGS. A total of 120 participants were further recruited in a validation cohort and divided into four subgroups, namely, normal controls (HC), PD with no dementia (PDND), PD with mild cognitive impairment (PD-MCI) and PDD. Among the six candidates, miR-203a-3p was successfully detected in the plasma of the validation cohort using droplet digital PCR (ddPCR). Our results show that the ratio of miR-203a-3p/miR-16-5p observed in PDD was significantly increased compared to in PD-MCI (p < 0.001) and PDND (p = 0.041). Moreover, the ratio of miR-203a-3p/miR-16-5p showed a significant correlation with MoCA scores (r = -0.237, p = 0.024) in patients with PD (PwP). The ROC curve of the logistic regression model, consisting of the variables of age, the ratio of miR-203a-3p/miR-16-5p and the UPDRS III score, also demonstrated an average AUC of 0.883 via 5-fold cross-validation. In conclusion, the ratio of miR-203a-3p/miR-16-5p may serve as a potential biomarker for distinguishing cognitive dysfunction from PwP.
Decoding Online Teeth Whitening Videos: Navigating Social Media Complexities
Authors: Tziovara Panagiota , Tzortzakaki Angeliki Styliani , Chatzidaki Zinovia , Antoniadou Maria
Published: January 2024

In the era of digital information consumption, YouTube has emerged as a prominent platform for disseminating knowledge across various domains. One such area that has gathered significant attention is teeth whitening, with a plethora of videos offering insights into professional proce-dures, home remedies, and personal experiences. This study delves into the vast landscape of teeth whitening content on YouTube, meticulously categorizing videos into professional and amateur domains. The aim is to critically analyze the information presented, considering its accuracy, re-liability, and potential impact on public perceptions and oral health choices. A total of 100 videos in Greek (n1= 73) and in English (n2= 27) were studied. The analysis was based on views, likes, publication year, duration, presence of background music, and the presence of a description. The completion date of the search was October 7, 2023. Professional videos predominantly present whitening as a painless, conservative, and economical procedure, emphasizing safety measures. Bleaching mechanisms involving hydrogen peroxide and carbamide are explored, with various application techniques discussed, including whitening strips, splints, and in-office procedures. Contradictory findings on the efficacy of home versus in-office treatments are highlighted. In-ternal and external discoloration factors are delineated, with contraindications specified. Amateur videos, garnering greater public appeal, present personal experiences, product promotions, and homemade remedies, reflecting a concerning trend of misinformation. The analysis incorporates viewer engagement metrics, emphasizing the impact of non-professional content. As social media platforms play an increasingly influential role in shaping healthcare narratives, understanding the nuances of dental discourse on YouTube becomes crucial for both practitioners and the public. This exploration encompasses a spectrum of topics, ranging from the chemical intricacies of bleaching agents to the societal dynamics influencing viewer preferences. By unraveling the complexities of online dental information, this study seeks to contribute valuable insights to the evolving land-scape of oral health education in the digital age. Future research should adopt a multi-platform approach and explore the dynamic interaction between content creators and viewers for a more holistic comprehension of online dental information.
Design and Implementation of a Smart Photovoltaic Hydroponic Greenhouse for Sustainable Agriculture in Tunisia
Authors: Marouani Rym , Khachroumi Sofiane , Chabakata Mahamat , Bouadila Salwa , Cherif Adnane
Published: January 2024

Sustainable agriculture has become increasingly important in Tunisia due to the drought that has been affecting the country's climate in recent years. This has become a major threat to the economy, making it necessary to explore alternative methods of agriculture that are more sustainable. Moreover, smart hydroponic cultivation based on renewable energies has become increasingly widespread, promoting the quality and efficiency of agricultural production despite weather parameters variations and global warming. This work aims to create a sustainable agriculture system in Tunisia through the design and implementation of a smart photovoltaic (PV) hydroponic greenhouse. The greenhouse will utilize advanced technology to optimize plant growth and reduce water usage, while also incorporating solar panels to generate renewable energy. The end goal is to create a self-sufficient and eco-friendly agricultural system that can provide fresh produce to local communities year-round. In this work, we are interested to the automation of the hydroponic greenhouse (HG)’s thermal conditioning system based on an asynchronous motor pump and powered by a PV generator. In the first stage, we analyzed the mathematical modeling of a stand-alone PV-HG system that consists of a PV generator, a three-phase inverter, an asynchronous motor pump, and a hydroponic system. After that, we developed a Field Oriented Control based on proportional integral (PI) regulators to adjust the rotation speed of the asynchronous motor pump, which aimed to provide the cooling and heating needs of the plant. The simulation results demonstrated the effectiveness of the proposed system . Additionally, we designed and implemented a smart system based on the internet of things (IoT) to enable remote control of internal and external parameters of the HG. This intelligent solution utilizes sensors, microcontrollers, and other devices and ensures the monitoring and the maintaining of the ideal growing conditions for our plants, guaranteeing that they receive the proper amount of temperature, humidity, and lighting. This type of system can be an invaluable tool for maximizing yields and achieving optimal results. With the right approach and attention to detail, we can create a sustainable and efficient growing environment that will help our plants flourish year-round.
Actuarial Analysis of Survival after Breast Cancer Diagnosis among Lithuanian Females
Authors: Levickytė Justina , Skucaitė Aldona , Šiaulys Jonas , Vincerževskienė Ieva
Published: January 2024

Breast cancer is the most common cause of mortality due to cancer for woman both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis and other factors. One way to estimate survival is to construct a Kaplan-Meier estimate for each factor value separately. However, in cases when it is impossible to observe a large number of patients (for example, in case of countries with lower numbers of inhabitants) dividing data into subsets, say, by stage at diagnosis may lead to results where some subsets contain too little data so that results of Kaplan Meier (or any other) method will become statistically incredible. The problem may become even more acute if the researcher would like to use more risk factors, such as stage at diagnosis, sex, place of living, treatment method, etc. Alternatively, Cox models are used to analyse survival data with covariates, and they don’t require dividing the data into subsets according to chosen risks factors (hazards).
Structural Analysis of Melanocytic Nevi
Authors: CHESCA ANTONELLA
Published: January 2024

The aim of the study is to identify structural characteristics of melanocytic nevi. In this context using microscope, could be possible a good describtion related melanocytic nevi, reffering to youth pacients.Jnowing the risk factors, one of the research direction is to have in attention the management options for melanocytic nevi. In this direction, implication of an interprofessional team strategies is one of the proper condition. Future directions refers to preventive and prophylactic methods.