bluuebunny/crossref_metadata_2025 huggingface dataset:
Serum Ferritin: A Backstage Weapon in Diagnosis of Dengue Fever
Authors: Roy Chaudhuri Soumyabrata , Bhattacharya Subhayan , Chakraborty Mainak , Bhattacharjee Kingshuk
Published: October 2017

Aims. This retrospective study evaluates ferritin as a surrogate marker for dengue infection (NS1 and IgM negative stage) as opposed to other febrile illnesses of infective or inflammatory etiology (OFI). Methodology. Data of all patients admitted to medical ward and medical ITU during the dengue outbreak were collected. Patients admitted between 5 and 10 days of febrile illness without a diagnosis were included. Patients with NS1 positivity (Days 2–8) and/or positive IgM for dengue (Days 6–10) were considered to be dengue cases and those with other confirmed diagnoses were considered in the OFI group. Ferritin, CRP, TC of WBC, platelet count, SGOT, SGPT, and albumin levels were analysed for both groups. Results. We examined 30 cases of clinically and serologically confirmed dengue fever and 22 cases of OFI. Ferritin level in dengue cohort was significantly higher than the OFI group (p<0.0001). The best cut-off for ferritin level to differentiate dengue from OFI was found to be 1291. The sensitivity at this cut-off is 82.6% and the specificity at this cut-off is 100%. Conclusion. Ferritin may serve as a significant marker for differentiating between dengue fever and OFI, in absence of a positive NS1 antigen or a positive IgM antibody for dengue.
Bulk Local Operators, Conformal Descendants, and Radial Quantization
Authors: Wang Zhao-Long , Yan Yi
Published: October 2017

We establish a construction of the bulk local operators in AdS by considering CFT at finite energy scale. Without assuming any prior knowledge about the bulk, the solution to the bulk free field equation automatically appears in the field theory arguments. In the radial quantization formalism, we find a properly regularized version of our initial construction. Possible generalizations beyond pure AdS are also discussed.
Learning to Detect Traffic Incidents from Data Based on Tree Augmented Naive Bayesian Classifiers
Authors: Li Dawei , Hu Xiaojian , Jin Cheng-jie , Zhou Jun
Published: October 2017

This study develops a tree augmented naive Bayesian (TAN) classifier based incident detection algorithm. Compared with the Bayesian networks based detection algorithms developed in the previous studies, this algorithm has less dependency on experts’ knowledge. The structure of TAN classifier for incident detection is learned from data. The discretization of continuous attributes is processed using an entropy-based method automatically. A simulation dataset on the section of the Ayer Rajah Expressway (AYE) in Singapore is used to demonstrate the development of proposed algorithm, including wavelet denoising, normalization, entropy-based discretization, and structure learning. The performance of TAN based algorithm is evaluated compared with the previous developed Bayesian network (BN) based and multilayer feed forward (MLF) neural networks based algorithms with the same AYE data. The experiment results show that the TAN based algorithms perform better than the BN classifiers and have a similar performance to the MLF based algorithm. However, TAN based algorithm would have wider vista of applications because the theory of TAN classifiers is much less complicated than MLF. It should be found from the experiment that the TAN classifier based algorithm has a significant superiority over the speed of model training and calibration compared with MLF.
A Comparison of Fishes and Invertebrates Living in the Vicinity of Energized and Unenergized Submarine Power Cables and Natural Sea Floor off Southern California, USA
Authors: Love Milton S. , Nishimoto Mary M. , Snook Linda , Schroeder Donna M. , Scarborough Bull Ann
Published: October 2017

Increasing reliance on deep-water renewable energy has increased concerns about the effects of the electromagnetic fields (EMFs) generated by submarine power cables on aquatic organisms. Off southern California, we conducted surveys of marine organisms living around energized and unenergized submarine power cables and nearby sea floor during 2012–2014 at depths between 76 and 213 m. In general, EMFs declined to background levels about one meter from the cable. We found no statistical difference in species composition between the fish assemblages along the energized and unenergized cables. The natural habitat community statistically differed from both energized and unenergized cable communities. Within species (or species groups), we found no differences in densities between energized and unenergized cables. Total fish densities were significantly higher around the cables than over the natural habitat. We found that invertebrate communities were structured by habitat type and depth and, similar to the fishes, there was no statistical difference between the energized and unenergized cables. Individually, the densities of four invertebrate species or species groups (Metridium farcimen, Luidia spp., unidentified black Crinoidea, and Urticina spp.) differed between energized and unenergized cables, but this difference was not significant across all depth strata. The invertebrate community inhabiting the natural habitat strongly differed from the energized and unenergized cable community exhibiting the fewest species and individuals.
Severe Undifferentiated Vasoplegic Shock Refractory to Vasoactive Agents Treated with Methylene Blue
Authors: Manji Farheen , Wierstra Benjamin , Posadas Juan
Published: October 2017

Methylene blue is a phenothiazine-related heterocyclic aromatic molecule presently used in the treatment of methemoglobinemia. Recently, it has been implicated in the treatment of severe refractory vasoplegic shock caused by anaphylaxis, sepsis, or postcardiopulmonary bypass. We present a case of a 27-year-old male with profound vasoplegic shock of unknown etiology which was refractory to vasopressors who responded within hours to a single dose of methylene blue. Additionally, we review the evidence of methylene blue’s role in the treatment of shock. This case illustrates a diagnostic approach and treatment options in the setting of undifferentiated vasodilatory shock and outlines a new and emerging role for methylene blue in this clinical setting.
Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane
Authors: Kromer Robert , Spitzer Martin Stephan
Published: October 2017

A precise evaluation of the retinal nerve fiber layer thickness (RNFLT) is key for diagnosing and monitoring glaucoma. The Bruch’s membrane opening minimum rim width (BMO-MRW) has been proposed as a reproducible assessment of the optic nerve. The BMO-MRW measures the minimum distance from the BMO to the internal limiting membrane. We propose an approach to correct the BMO-MRW using the BMO size for increased accuracy in interindividual comparisons in future studies. Eighty-one healthy patients received SPECTRALIS spectral domain optical coherence tomography measurements for the peripapillary RNFLT and BMO-MRW. We calculated a BMO size-corrected BMO-MRW using the mean BMO size of our cohort. BMO size was defined using the manufacturer-provided BMO area and manually measured BMO perimeter. We observed that the BMO-MRW correlated highly with the perimeter (r=−0.553, p<0.0001) and the area of the BMO (r=−0.546, p<0.0001). Using these parameters, we provided a corrected BMO size-adjusted BMO-MRW which was better correlated with the RNFLT compared to the noncorrected one (z=−3.3495, p=0.0004). We demonstrated the dependency of the BMO-MRW on ONH size. Furthermore, we showed the superiority of the corrected BMO-MRW using either the manually measured optic nerve head perimeter or the automatically provided ONH for future studies.
Changes in Somatostatin-Like Immunoreactivity in the Sympathetic Neurons Projecting to the Prepyloric Area of the Porcine Stomach Induced by Selected Pathological Conditions
Authors: Palus Katarzyna , Bulc Michał , Całka Jarosław
Published: October 2017

The aim of the present study was to define changes in the expression of somatostatin (SOM) in the sympathetic perikarya innervating the porcine stomach prepyloric area during acetylsalicylic-acid-induced gastritis (ASA) and experimentally induced hyperacidity (HCL) and following partial stomach resection (RES). On day 1, the stomachs were injected with neuronal retrograde tracer Fast Blue (FB). Animals in the ASA group were given acetylsalicylic acid orally for 21 days. On the 22nd day after FB injection, partial stomach resection was performed in RES animals. On day 23, HCL animals were intragastrically given 5 ml/kg of body weight of a 0.25 M aqueous solution of hydrochloric acid. On day 28, all pigs were euthanized. Then, 14-μm thick cryostat sections of the coeliac-superior mesenteric ganglion (CSMG) complexes were processed for routine double-labelling immunofluorescence. All pathological conditions studied resulted in upregulation of SOM-like (SOM-LI) immunoreactivity (from14.97±1.57% in control group to33.72±4.39% in the ASA group, to39.02±3.65% in the RES group, and to29.63±0.85% in the HCL group). The present studies showed that altered expression of SOM occurs in sympathetic neurons supplying the prepyloric area of the porcine stomach during adaptation to various pathological insults.
PI3Kγ Activates Integrin α4 and Promotes Immune Suppressive Myeloid Cell Polarization during Tumor Progression
Authors: Foubert Philippe , Kaneda Megan M. , Varner Judith A.
Published: September 2017

Immunosuppressive myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) accumulate in tumors where they inhibit T cell–mediated antitumor immune responses and promote tumor progression. Myeloid cell PI3Kγ plays a role in regulating tumor immune suppression by promoting integrin α4–dependent MDSC recruitment to tumors and by stimulating the immunosuppressive polarization of MDSCs and TAMs. Here, we show that integrin α4 promotes immunosuppressive polarization of MDSCs and TAMs downstream of PI3Kγ, thereby inhibiting antitumor immunity. Genetic or pharmacological suppression of either PI3Kγ or integrin α4 blocked MDSC recruitment to tumors and also inhibited immune suppressive myeloid cell polarization, thereby reducing expression of IL10 and increasing expression of IL12 and IFNγ within tumors. Inhibition of PI3Kγ or integrin α4 within tumors stimulated dendritic cell and CD8+ T-cell recruitment and maturation, as well as tumor cell cytotoxicity in vivo, thereby inhibiting tumor growth. As blockade of PI3Kγ or integrin α4 prevents accumulation of MDSC and reduces myeloid cell expression of immunosuppressive factors that stimulate tumor immune escape, these results highlight PI3Kγ and integrin α4 as targets for the design of cancer therapeutics. Cancer Immunol Res; 5(11); 957–68. ©2017 AACR.
The Rumor Mill or “How Rumors Evade the Grasp of Research”
Authors: Schmid Jimmy , Klingemann Harald , Bandyopadhyay Boris , Scheuermann Arne
Published: October 2017

Shifts between concepts of “graphic design” and “visual communication” offer numerous topical links and demonstrate their relevance for our research question: “How can communication designers design and steer rumor-based communication?” An interdisciplinary research team at the Bern University of the Arts (HKB) launched the project “Gerüchtekuchee” (“Rumour mill”) and conducted an experiment by planting a real-life rumor in organizational context. Results together with evidence from a literature review informed a practice application—“The Rumor Fighter”—as part of a museum exhibition, Gerücht: Museum für Kommunikation [Rumor: Museum of Communication], in Bern, Berlin, Frankfurt.
Migration and Cultural Contact in the Emergence of Rus’-land, Sixth to Nineteenth Centuries
Authors: Hoerder Dirk
Published: October 2017

Migrations in the intercontinental macro-region have been studied as proto-Slavic early settlement; as transit zone for Varangian-Arab trade and Byzantine-Kiev interactions; as space of Mongolian intrusion and as a territorially integrated Muscovite state with rural populations immobilised as serfs. This article integrates migrations from and to the neighbouring Scandinavian, East Roman, and Steppe macro-regions up to the fifteenth century and, more briefly, from the sixteenth to nineteenth centuries. In these poly-ethnic worlds, resident and in-migrant cultural groups adapted in frames of intercultural contact, migration, hierarchies, processes of power imposition and of exchange. An important facet is the ‘small numbers-large impact’ character of many migrations before the advance of Mongol/Tatar armies. From the fifteenth century, elites of the new Muscovite state such as traders and colonisers moved east into Siberia’s societies and attracted technical and administrative personnel from German-language societies. The traditional historiographical narrative, centred on an east-west perspective, is expanded to include the north-south axes of migration and cultural contact.
Clicking Into Harm’s Way: The Decision to Purchase Regulated Goods Online
Authors: Kennedy Jay P. , Wilson Jeremy M.
Published: September 2017

The growth of the Internet has expanded e-commerce, opening a vast array of purchasing options for consumers while also increasing illicit sales. Such sales place consumers at risk. This study examines consumers’ decisions to purchase cigarettes and prescription pharmaceuticals, two highly regulated goods, from online vendors. Drawing on a statewide survey of nearly 1,000 residents in Michigan, we assess the prevalence of Internet purchases of these goods, the differences between those who make these purchases online and those who do not, and the factors associated with Internet purchase decisions. In general, it was discovered that the prevalence of Internet purchases of these goods is relatively low, but the frequency with which the sales are illicit is relatively high. Additionally, the factors that explain the decision by consumers to purchase these items online and their reasons for doing so vary by product type. The study offers a discussion of these findings and their implications for crime prevention and further research.
Effect of a musical instrument performance program on emotional intelligence, anxiety, and aggression in Korean elementary school children
Authors: Kim Hyun-Sil , Kim Hun-Soo
Published: September 2017

The purpose of this study was to determine the effects of a musical instrument performance program on emotional intelligence, anxiety, and aggression in Korean elementary school children. A quasi-experimental study design was employed, in which the experimental group ( n = 30) received a weekly group musical instrument performance class with a regular music class, and the control group ( n = 30) received only a regular music class that is part of the elementary school curriculum. We measured emotional intelligence, anxiety, and aggression at the beginning and end of the 24-week intervention using the Emotional Intelligence Scale, the Trait Anxiety Inventory, and the Aggression Scale. The musical instrument performance program improved the ability to perceive emotions, and reduced physical and verbal aggression, but had no statistically significant effect on the level of total emotional intelligence, anxiety, or aggression.
Gaining Acceptance by Informing the People? Public Knowledge, Attitudes, and Acceptance of Transportation Policies
Authors: Li Menghan , Zhao Jinhua
Published: September 2017

We examine the connection between public knowledge and attitudes in the context of urban transportation policies. We categorize policy knowledge into received, subjective, and reasoned knowledge, and measure them empirically using a survey of Shanghai’s residents (n=1,000) on the vehicle license auction policy. We quantify the relationship between the three types of knowledge and public acceptance and its predecessors (perceived effectiveness, affordability, and equity). We find variegated impacts of knowledge on acceptance: reasoned knowledge increases acceptance but subjective knowledge decreases it, while received knowledge has no direct impact. Public information needs to emphasize societal benefits and the underlying policy rationale.
Intervening in a “Sketchy Situation”: Exploring the Moral Motivations of College Bystanders of Sexual Assault
Authors: Gable Samuel C. , Lamb Sharon , Brodt Madeline , Atwell Leah
Published: September 2017

This mixed-methods research explored the moral motivations of undergraduates who identified as bystanders in a situation of potential sexual assault. In the quantitative analysis, we examined the difference between interveners and noninterveners with regard to their scores on the Moral Foundations Questionnaire–30 Item (MFQ-30), which considers five moral foundations from Moral Foundations Theory (MFT) of care/harm, fairness/cheating, loyalty/betrayal, authority/subversion, and sanctity/degradation, as well as measures of bystander attitudes (BAS-R) and rape-myth acceptance (IRMA, modified). Participants who failed to intervene had significantly higher scores on the loyalty/betrayal subscale of the MFQ-30, and showed a trend toward “conservative” values comprising the latter three MFT foundations. Intervening bystanders were also more likely to endorse bystander attitudes, and less likely to endorse rape-myth supporting beliefs. The qualitative analysis examined brief narratives in which participants described their bystander experience and reasoning in the moment. Analysis found a remarkable flexibility with which each moral foundation could be used to support either intervention or abstention. We argue that emphasizing conservative values (based on loyalty, purity, and/or authority) in addition to the typical liberal (justice-based and anti-harm) reasoning may bolster bystander interventions meant to reach all students.
Photovoice Ethics: Critical Reflections From Men’s Mental Health Research
Authors: Creighton Genevieve , Oliffe John L. , Ferlatte Olivier , Bottorff Joan , Broom Alex , Jenkins Emily K.
Published: September 2017

As photovoice continues to grow as a method for researching health and illness, there is a need for rigorous discussions about ethical considerations. In this article, we discuss three key ethical issues arising from a recent photovoice study investigating men’s depression and suicide. The first issue, indelible images, details the complexity of consent and copyright when participant-produced photographs are shown at exhibitions and online where they can be copied and disseminated beyond the original scope of the research. The second issue, representation, explores the ethical implications that can arise when participants and others have discordant views about the deceased. The third, vicarious trauma, offers insights into the potenial for triggering mental health issues among researchers and viewers of the participant-produced photographs. Through a discussion of these ethical issues, we offer suggestions to guide the work of health researchers who use, or are considering the use of, photovoice.
Altruism and Collectivism: An Exploratory Study in Four Cultures
Authors: Munroe Robert L.
Published: September 2017

This exploratory study tries to interpret the results of a test of altruism among almost 200 children from four small-scale societies in Belize, Kenya, Nepal, and American Samoa. Samoan children and, to a lesser extent, Nepalese Newar children were altruistic in a dictator game test. We considered evidence that the four settlements varied according to a collectivistic dimension and that such collectivism may have strongly influenced responses to the test. Not only did test results correspond fully to degree of community collectivism across the four cultures (rank-order correlation coefficient = 1.00, p < .05, N = 4), but Samoan children also scored at the highest level across each age group from 3 to 9 years of age, and the Nepalese Newar participants scored at the second highest level at all ages. We posit that social and material conditions in Samoa and Nepal were likely sources of collectivism and, concomitantly, the strong altruistic tendencies but acknowledge that in exploratory research there will always be issues concerning interpretation.
Using Art for Health Promotion: Evaluating an In-School Program Through Student Perspectives
Authors: McKay Fiona H. , McKenzie Hayley
Published: September 2017

The value of incorporating arts-based approaches into health promotion programs has long been recognized as useful in affecting change. Such approaches have been used in many schools across Australia and have been found to promote general well-being and mental health. Despite these positive findings, few programs have used or evaluated an integrated arts-based approach to achieve health and well-being goals. This article presents the findings of an evaluation of an integrated arts-based program focused on creativity and improving well-being in students. The findings of this evaluation suggest that students who took part in the program were more interested in art and music at the end of the program and had gained an overall increase in awareness and mindfulness and a positivity toward leisure activities. This evaluation provides some evidence to suggest that this type of program is a promising way to promote well-being in schools.
Serosal Laceration During Firing of Powered Linear Stapler Is a Predictor of Staple Malformation
Authors: Matsuzawa Fumihiko , Homma Shigenori , Yoshida Tadashi , Konishi Yuji , Shibasaki Susumu , Ishikawa Takahisa , Kawamura Hideki , Takahashi Norihiko , Iijima Hiroaki , Taketomi Akinobu
Published: September 2017

Background. Although several types of staplers have been developed, staple-line leaks have been a great problem in gastrointestinal surgery. Powered linear staplers were recently developed to further reduce the risk of tissue trauma during laparoscopic surgery. The aim of this study was to identify the factors that predict staple malformation and determine the effect of precompression and slow firing on the staple formation of this novel powered stapling method. Methods. Porcine stomachs were divided using an endoscopic powered linear stapler with gold reloads. We divided the specimens into 9 groups according to the precompression time (0/60/180 seconds) and firing time (0/60/180 seconds). The occurrence and length of laceration and the shape of the staples were evaluated. We examined the factors influencing successful stapling and investigated the key factors for staple malformation. Results. Precompression significantly decreased the occurrence and length of serosal laceration. Precompression and slow firing significantly improved the optimal stapling formation rate. Univariate analysis showed that the precompression time (0 seconds), firing time (0 seconds), and presence of serosal laceration were significantly associated with a low optimal formation rate. Multivariate analysis showed that these three factors were associated independently with low optimal formation rate and that the presence of serosal laceration was the only factor that could be detected during the stapling procedure. Conclusions. We have shown that serosal laceration is a predictor of staple malformation and demonstrated the importance of precompression and slow stapling when using the powered stapling method.
First-in-human response of BCL-2 inhibitor venetoclax in T-cell prolymphocytic leukemia
Authors: Boidol Bernd , Kornauth Christoph , van der Kouwe Emiel , Prutsch Nicole , Kazianka Lukas , Gültekin Sinan , Hoermann Gregor , Mayerhoefer Marius E. , Hopfinger Georg , Hauswirth Alexander , Panny Michael , Aretin Marie-Bernadette , Hilgarth Bernadette , Sperr Wolfgang R. , Valent Peter , Simonitsch-Klupp Ingrid , Moriggl Richard , Merkel Olaf , Kenner Lukas , Jäger Ulrich , Kubicek Stefan , Staber Philipp B.
Published: October 2017

Key Points

Strong responses to venetoclax separate T-PLL from other hematologic malignancies in high- throughput drug screening of clinical samples. Two relapsed and refractory T-PLL patients demonstrated clinical response on venetoclax treatment.
Invited commentary on … When unbearable suffering incites psychiatric patients to request euthanasia: A qualitative study
Authors: Pearce Steve
Published: October 2017

Although the paper in this issue by Verhofstadtet alsheds some light on the features of unbearable suffering stemming from psychiatric disorder leading to a request for euthanasia, this is limited. The bulk of the paper illustrates the particular ethical challenges posed by the policy of making euthanasia available in these circumstances.
Personality disorder services in England: findings from a national survey
Authors: Dale Oliver , Sethi Faisil , Stanton Clive , Evans Sacha , Barnicot Kirsten , Sedgwick Rosemary , Goldsack Steve , Doran Monica , Shoolbred Lucinda , Samele Chiara , Urquia Norman , Haigh Rex , Moran Paul
Published: October 2017

Aims and method

We aimed to evaluate the availability and nature of services for people affected by personality disorder in England by conducting a survey of English National Health Service (NHS) mental health trusts and independent organisations.

Results

In England, 84% of organisations reported having at least one dedicated personality disorder service. This represents a fivefold increase compared with a 2002 survey. However, only 55% of organisations reported that patients had equal access across localities to these dedicated services. Dedicated services commonly had good levels of service use and carer involvement, and engagement in education, research and training. However, a wider multidisciplinary team and a greater number of biopsychosocial interventions were available through generic services.

Clinical implications

There has been a substantial increase in service provision for people affected by personality disorder, but continued variability in the availability of services is apparent and it remains unclear whether quality of care has improved.
A GAP that Divides
Authors: Basant Angika , Glotzer Michael
Published: October 2017

Cytokinesis in metazoan cells is mediated by an actomyosin-based contractile ring that assembles in response to activation of the small GTPase RhoA. The guanine nucleotide exchange factor that activates RhoA during cytokinesis, ECT-2, is highly regulated. In most metazoan cells, with the notable exception of the earlyCaenorhabditis elegansembryo, RhoA activation and furrow ingression require the centralspindlin complex. This exception is due to the existence of a parallel pathway for RhoA activation inC. elegans. Centralspindlin contains CYK-4 which contains a predicted Rho family GTPase-activating protein (GAP) domain. The function of this domain has been the subject of considerable debate. Some publications suggest that the GAP domain promotes RhoA activation (for example, Zhang and Glotzer, 2015; Loria, Longhini and Glotzer, 2012), whereas others suggest that it functions to inactivate the GTPase Rac1 (for example, Zhuravlevet al., 2017). Here, we review the mechanisms underlying RhoA activation during cytokinesis, primarily focusing on data inC. elegans.We highlight the importance of considering the parallel pathway for RhoA activation and detailed analyses of cyk-4mutant phenotypes when evaluating the role of the GAP domain of CYK-4.
Engineering design. Metal structures and constructions from wood and plastics
Authors: Дукарский Юлиан , Dukarskiy Yulian , Расс Федор , Rass Fedor , Мареева Ольга , Mareeva Ol'ga
Published: October 2017

In the textbook "Engineering design. Metal structures and constructions from wood and plastics" outlines General information about engineering structures of buildings and constructions of steel, wood and plastics, examined physical and mechanical properties of these structural materials. The main principles of analysis of steel structures, wood and plastics in accordance with applicable building codes. The fundamentals of designing and calculation of designs of buildings and constructions of water supply and environmental purposes, considers special requirements of hydraulic engineering constructions, exposed to prolonged exposure to the aquatic environment. Provides references, examples of calculations and test questions.
The textbook "Engineering design. Metal structures and constructions from wood and plastics" is the first part of the fourth revised and augmented edition for higher education institutions, and written in accordance with modern design standards the designs of the basic building materials. The textbook "Engineering design. Metal structures and constructions from wood and plastics" is intended for students of higher educational institutions studying in areas of training 08.03.01 "Construction" 20.03.02 "Environmental engineering and water management". The material presented in the textbook used for the formation of knowledge, skills and professional competences necessary for professional activities in the field of the theory and practice of analysis and design of engineering structures of buildings and structures for various purposes, used in construction.
Methodological feature of the present edition is a concise form of presentation, which greatly facilitates its absorption with the requirements of the engineering disciplines, study programs for bachelors. The textbook "Engineering design. Metal structures and constructions from wood and plastics" meets the requirements of Federal state educational standard of higher education of the last generation.
The textbook "Engineering design. Metal structures and constructions from wood and plastics" consists of the first (introductory) Chapter provides General information about engineering structures and two sections. The first section is devoted to metal structures, the second section is about the structures of wood and plastic.
On the fourth edition of the textbook work: Chapter 1 — Professor Yu. M. Dukarsky; section I and applications — Professor Yu. M. Dukarsky and associate Professor O. V. Mareeva; section II — Professor F. V. Russ.
Newspaper trust and credibility in the age of robot reporters
Authors: Schultz Brad , Sheffer Mary Lou
Published: October 2017

Audience perception of trust and credibility related to computer-generated journalism was investigated through a national survey of news consumers. Results indicated significantly negative attitudes towards news stories produced by computer algorithms rather than human journalists, and that both credibility and trust were key predictive factors in such attitudes. Implications for the newspaper industry were discussed, including a greater need for newspaper transparency and audience education.
Caring for cancer survivors with the popular expressive arts
Authors: Quinlan Elizabeth , Robertson Susan , Fitchner Pam
Published: October 2017

Research has demonstrated considerable health benefits derived from incorporating the arts in health care. Yet, the process of translating research knowledge into clinical practice requires a sensitive understanding of the practice context. In this article, we consider the challenges to clinicians’ integration of the popular, expressive art forms into their practice. We assess these art forms for their potential value for the health and well-being of breast cancer survivors in light of the implementation challenges, as perceived by surveyed health care practitioners. Over 90 per cent of the responding practitioners deemed the popular expressive arts to have healing potential for people with cancer. While surveyed clinicians believe in the health benefits of arts, they report considerable challenges to incorporating the creative arts into their practices. We conclude by advocating for clinicians’ education, expanded scopes of practice, further research and a reorganization of clinical work so that clinicians can integrate the arts into their practices.
Part 4
Authors: Stengers Isabelle , Davis Christine , Lyall Scott , Serres Michel , Massumi Brian , Didi-Huberman Georges
Published: October 2017

Entries: Sea Noise, Sensa, Proteus, Black Glass, Techniques of Existence, Prehension, Puffs of Existence, The Close-Up, Pan de Mur Jaune, Concrescence, The Infra-Thin. Includes text by Isabelle Stengers, Christine Davis, Scott Lyall, Michel Serres, Brian Massumi, Georges Didi-Huberman. Artworks by Scott Lyall, Glenn Ligon, Annie Besant and Charles Leadbeater, Annika von Hausswolff, Scott Treleaven, Diane Morin.
Akram Zaatari, All is Well
Authors: Georgis Dina
Published: October 2017

Review of Akram Zaatari, All is Well, curated by Vicki Moufawad Paul, Agnes Etherington Art Centre, Kingston, UK, 23 November 2013 – 30 March 2014.
The Violence of the Image: Photography and International Conflict
Authors: Vanderwees Chris
Published: October 2017

Review of The Violence of the Image: Photography and International Conflict (2014), Liam Kennedy and Caitlin Patrick (eds), New York: I.B. Taurus, 274 pp., p/bk, ISBN: 9781780767895.
From Havana Portraits from an Intimate Outsider
Authors: Dubinsky Karen
Published: October 2017

Canadian scholar Karen Dubinsky on Cuba-Canada pasts and present from her forthcoming book about Havana.
Some thoughts on the right way (for us) to love the Cuban Revolution
Authors: Weiss Rachel
Published: October 2017

Article on the projections of the US Left on the Havana of the 1960s.
Mapping stakeholder positions in the Kenyan land reform process
Authors: K’Akumu O. A.
Published: October 2017

The debate on land reform in sub-Saharan Africa has moved from the purpose and direction of reforms to the reasons why proposed reforms are not being implemented. The literature shows that one of the reasons for failure to implement reforms is conflicting stakeholder interests. This article proposes stakeholder analysis as a management tool that may be used to solve this problem. It goes ahead to apply the tool as a demonstration of how stakeholder analysis can resolve some of the conflicts involving stakeholder actions. These include a multi-level mapping of stakeholder characteristics for the land reform process in Kenya, a tri-attribute mapping of stakeholder characteristics, and a stakeholder mapping according to the six generic management strategies. This would help the implementing agency in carrying out the reform process successfully in Kenya.
O Uso de Fitoterápicos como auxílio no Tratamento de Enfermidades do Trato Digestório
Authors: Ribeiro Eva Ivaldina Schaus , Hass Caroline , Gaspareto Janaina Cristina Iensen , Zwierzykowski Thailyza , Santos Thaliny , Mazur Caryna Eurich
Published: October 2017

O presente artigo visa discutir a importância da utilização de fitoterápicos para tratamento de doenças relacionadas ao trato digestório. Para tanto, utilizou-se de pesquisa bibliográfica para identificar quais plantas poderiam ser utilizadas com benefícios a esta região corpórea e averiguar em que medida poderiam apresentar toxicidade ao corpo humano. Neste momento, chegou-se ao número de sete plantas fitoterápicas, com seus benefícios elencados.
Marketing Digital e a Rede Social Facebook nos Serviços Turísticos: uma investigação sobre a interação entre os consumidores finais e a companhia aérea LATAM
Authors: Oliveira Ada Lílian E Silva de , Durão André Falcão , Silveira Carla Borba da Mota
Published: October 2017

Nos últimos anos, em termos de possibilidades tecnológicas de comunicação, as redes sociais são quase onipresentes na vida das pessoas e ações estratégicas das empresas. Esta onipresença é fácil de observar na prestação de serviços turísticos. Neste cenário, o principal objetivo desta pesquisa foi analisar como a interação entre LATAM companhia aérea e os seus clientes através de sua página oficial na rede social Facebook. Os construtos marketing digital, redes sociais e uso redes sociais nos serviços de turismo deram suporte argumentativo teórico ao trabalho. Como procedimento metodológico, foram utilizados tendo em conta a abordagem qualitativa e interpretativa de pesquisa, a netnografia e observação não participante como uma maneira de explorar o comportamento dos consumidores on-line e conteúdo publicado por um período de seis meses. A partir da classificação de cargos da empresa e sua interação com os consumidores, os resultados indicam que o uso do Facebook como ferramenta de comunicação, promoção e relacionamento LATAM precisa ser melhorado. Há ainda benefícios potenciais significativos desta interação inexplorados. No entanto, existem aspectos positivos como respostas rápidas às demandas negativas dos usuários, como também o projeto de modernização de design da rede social e a promoção de vendas por impulso.
Perfil dos Pacientes com Diagnóstico de Câncer de Cabeça e Pescoço atendidos em Hospital Especializado de Recife – PE, no ano de 2014
Authors: Neves Carlos Neves Pereira de Brito , Raposo André Pereira Gomes , Bezerra Phelipe Cunha
Published: October 2017

Os cânceres de cabeça e pescoço tem crescido no mundo inteiro. São cerca de 200 mil pessoas por ano. Em termos de localização, os cânceres de cavidade oral, possuem uma incidência média de 13.470 novos casos novos por cada 100 mil habitantes, somente no Brasil.  O objetivo do presente estudo foi analisar o perfil dos pacientes que tiveram câncer de cabeça e pescoço e que foram atendidos no hospital de câncer de Pernambuco no ano de 2014. Este estudo analisou 560 pacientes no ano de 2014, em um hospital especializado de Recife, Pernambuco, Brasil. As variáveis analisadas incluíram sexo, idade, histórico de consumo de álcool e cigarro, diagnóstico, localização do tumor, o tipo do tumor,  primeiro tratamento recebido e desfecho deste tratamento. Os resultados demonstraram que a amostra foi predominantemente de homens (76,1%), de cor da pele parda (68,6%), tabagistas (59,5%), etilistas (51,4%) com idades entre 50 e 59 anos (32,5%), sendo que 61,2% possui nível de instrução fundamental.  O local do tumor mais prevalente foi C02.9 (17,3%), o tipo histológico 807013 (80,5%) e o local da metástase mais prevalente foi C77 em 85,5% dos casos. Conclusões: Este estudo reafirma achados da literatura sobre a temática, bem como contribui para um maior conhecimento sobre as características dos pacientes atendidos num hospital especializado em Recife. Certamente uma grande contribuição para que se possa traçar políticas públicas mais adequadas para este tipo de doença.
PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS: NEW STRATEGY, NEW TARGETS
Authors: Nasonov E. L.
Published: September 2017

Rheumatoid arthritis (RA) is a chronic immunoinflammatory (autoimmune) disease manifested by progressive joint destruction, systemic inflammation of the internal organs, and a wide range of comorbidities associated with chronic inflammation and frequently with adverse drug reactions. However, despite the major advances in the early diagnosis and treatment of RA, which have led to the radical improvement of prognosis in many patients, the problem of pharmacotherapy for RA is far from being solved. This is determined by a lack of sensitive and specific diagnostic and prognostic biomarkers in the early stage of the disease and, most importantly, by the heterogeneity of immunopathogenesis mechanisms in both at the onset of RA and during its progression, which make the personalization of therapy difficult in the patients. Selective block of inflammatory mediators with innovative medicines is frequently associated with primary inefficiency, secondary drug resistance, the development of generalized immunosuppression, the paradoxical activation of an autoimmune process, and the aggravation of comorbidities. At the same time, it is difficult to search for new RA pharmacotherapy targets since the nature of immunopathological disorders in patients can be substantially different from the inflammatory process that takes place when simulating arthritis in laboratory animals. The paper discusses the novel drugs that are used in rheumatology to treat RA or tested in different phases of preclinical or clinical trials, such as tumor necrosis factor-α inhibitors, interleukin-6 (IL-6), IL-17, anti-B cell therapy, bispecific antibodies, blockers of JAK (and other signaling molecules), bioelectronic vagus nerve activation, dendritic cell-based immunotherapy, and other therapies, as well as approaches to secondary prevention of RA in patients with undifferentiated arthritis and clinically suspect arthralgia, who are at high risk for RA. Decoding the mechanisms underlying the pathogenesis of RA and a chronic inflammatory process as a whole has created preconditions for the design of novel medications for the prevention and treatment of this disease, the introduction of which into clinical practice should lead to a radical improvement of prognosis in this disease.
DIET IN GOUT AND HYPERURICEMIA
Authors: Zhelyabina O. V. , Eliseev M. S.
Published: September 2017

The paper reviews the most important works devoted to the study of the impact of individual foods and food components on the risk of gout, its clinical manifestations and the level of uricemia. It considers some mechanisms probably underlying the impact of dietary patterns on the level of uricemia. It is shown that the available data on possible alterations in the diet with their proper application can considerably affect both the incidence of gout and the course of the current disease.
Lung cancer: analysis of biomarkers and methods of diagnostic and prognostic value
Authors: Yadav S. , Agrawal S. , Divya Ravali S. S. , Pandey A.
Published: October 2017

This paper summarizes the overwhelming evidence that targeted therapy is better than chemotherapy for the treatment of lung cancer. The focus is on lung cancer because of the sheer magnitude of this disease especially in males. In India, lung cancer constitutes 6.9 per cent of all new cancer cases and 9.3 per cent of all cancer related deaths in both sexes (1). Currently the world we reside has a norm of developing cure to an abnormal state of living body (so called disease) based on evidences, recognized during the diagnosis of the disease. It is done to ensure optimized therapy of treatment and maximize the outcome. Personalized medicine is also an uprising norm. In this kind, all the variables such as host, environment, patient, etc. are considered for an individual case and the course of treatment is followed based on the standard options available. Its main objective is the best interest of the patient. Through a survey conducted in the northern belt of the country we tried to determine the biomarkers currently being used and the scope of targeted therapy. Thus, in its most basic form medicine is not only a science but is also an art.
Migration and Welfare Systems – State of the Art and Research Challenges
Authors: Jakubiak Igor
Published: September 2017

Immigration is one of the heavily discussed subjects in modern academic and political debate. In recent decades, fiscal effects of international migration remained the centre of interest. The goal of this paper is to review and synthesise the available literature, devoted to the relationship between immigration and welfare systems, in order to present the state of the art in this area and draw conclusions for further research. Despite extensive literature, it is difficult to find an unambiguous answer to the question, whether immigrants are a burden or an asset to the state with redistributive policies. Moreover, some of the assumptions and approaches widely used in presented articles appear too simplistic or even unfounded.
Assyriology and Stalinism: Soviet Historiography and the Invention of Slavery in the Ancient Near East
Authors: Krikh Sergey
Published: September 2017

This article analyzes the main reasons why Soviet historiography developed a theory that the ancient Near East was characterized by an economy based on slavery. It explores the interplay of external and internal factors leading to the special role of Assyriology in that process, particularly through the work of the Russian and Soviet orientalist Vasiliy Struve.
Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway
Authors: Freis Alexander , Keller Andreas , Ludwig Nicole , Meese Eckart , Jauckus Julia , Rehnitz Julia , Capp Edison , Strowitzki Thomas , Germeyer Ariane
Published: October 2017

Main goal of this study is to detect the possible alterations in microRNA (miRNA) expression and the pathway targeted in plasma at the time of embryo transfer and pregnancy testing dependent on the assisted reproductive treatment (ART) outcome after ovarian hyperstimulation for in vitro fertilization. Changes in miRNA expression in plasma of women, who became pregnant (n = 6) vs women who failed implantation (n = 6) following day 5 embryo transfer (ET), were investigated at the day of ET and pregnancy testing (PT). Protein expression to validate the finding was performed with a sample size of n = 20 (10 per group) using enzyme-linked immunosorbent assay. Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed using DIANA-miRPath, v3.0 software based on predicted targets by DIANA-microT-CDS. 4 miRNAs could be identified as possible biomarkers for implantation success. The 11 miRNAs showing the highest significant alterations were all associated with the regulation of WNT3 and WNT7a. While WNT7a presented with a significant decrease between ET and PT in case of ongoing pregnancy, women with implantation failure showed unaltered concentrations. WNT3 presented with a significant decrease in both groups. However, the loss of WNT3 between ET and PT was significantly higher in patients who became pregnant. Main limitation of this prospective study is its small sample size, defining it as a pilot analysis. To conclude, we could demonstrate a significant change in miRNA profile dependent on the ART outcome affecting Wnt pathway. Our findings indicate a possible prospective use of miRNA as biomarkers for implantation success.
The Exclusivism of Religion Teachers: Intolerance and Radicalism in Indonesian Public Schools
Authors: Maulana Dirga
Published: October 2017

In the context of Indonesianism and Islamism, religion teachers serve as avant garde of tolerance, which is then manifested into their social contexts. The attitude of religious tolerance and inclusivity are must have for religion teachers; since these teachers have the closest connection to their students who are mostly young people. We have observed that the increasing radicalism in educational institutions has been associated with particular models of interpretation, understanding, teaching, schools of thoughts, denomination, and even sects within a particular religion. For instance, an international agency has reported the discovery of an "intolerance curriculum" in Saudi Arabian schools (Freedom House, 2006).In Indonesia, the growth of radicalism was due to scriptural, rigid, exclusive, and close-minded interpretation towards religious scripts. In 2008, PPIM (Center for the Study of Islam and Society) UIN Syarif Hidayatullah Jakarta released an important finding that "the majority of religion teachers in Indonesian public schools have exclusive and conservative view towards religion."DOI: 10.15408/sdi.v24i2.5707