bluuebunny/crossref_metadata_2025 huggingface dataset:
Fluid Resuscitation and Sepsis Management in Patients with Chronic Kidney Disease or End-Stage Renal Disease: Scoping Review
Authors: Haley Matt , Foroutan Nasim Khosravi , Gronquist Juliann M. , Reddy Raju , Wusirika Raghav , Khan Akram
Published: January 2024

Managing sepsis and fluid resuscitation in patients with chronic kidney disease or end-stage renal disease is challenging for health care providers. Nurses are essential for early identification and treatment of these patients. Nurse education on assessing perfusion and implementing 3-hour bundled care can improve mortality rates in patients with sepsis. In this scoping review, initial screening identified 1176 articles published from 2015 through 2023 in the National Library of Medicine database; 29 articles were included in the literature summary and evidence synthesis. A systematic review meta-analysis was not possible because of data heterogeneity.

The review revealed that most patients with chronic kidney disease or end-stage renal disease received more conservative resuscitation than did the general population, most likely because of concerns about volume overload. However, patients with chronic kidney disease or end-stage renal disease could tolerate the standard initial fluid resuscitation bolus of 30 mL/kg for sepsis. Outcomes in patients with chronic kidney disease or end-stage renal disease were similar to outcomes in patients without those conditions, whether they received standard or conservative fluid resuscitation. Patients who received the standard (higher) fluid resuscitation volume did not have increased rates of complications such as longer duration of mechanical ventilation, increased mortality, or prolonged length of stay. Using fluid responsiveness to guide resuscitation was associated with improved outcomes.

The standard initial fluid resuscitation bolus of 30 mL/kg may be safe for patients with chronic kidney disease or end-stage renal disease and sepsis. Fluid responsiveness could be a valuable resuscitation criterion, promoting better decision-making by multidisciplinary teams. Further research is required.
Use of the 3 Wishes Project to Help Individualize End-of-Life Care in a Medical Intensive Care Unit
Authors: Harrison Brittany H. , Hundt Elizabeth , Wiencek Clareen
Published: January 2024

Background

Multiple organizations recommend that individualized end-of-life (EOL) care should be standard practice. However, a standardized approach does not exist because EOL care should be individually tailored. The 3 Wishes Project is an EOL intervention that provides direction for individualized care with 3 goals: dignify death, celebrate the patient’s life, and support family members and the intensive care unit clinicians caring for the patient. Patients and families are given the opportunity to choose 3 wishes during the dying process.

Objective

To ascertain if the implementation of the 3 Wishes Project allowed the medical team to provide individualized EOL care.

Methods

The Iowa Model was used for this evidence-based project. The project was implemented in the medical intensive care unit at an academic medical center. Outcomes were evaluated by the collection and analysis of qualitative and quantitative data.

Results

From the 57 patients who died during the 2-month implementation period, 32 wish forms were collected; 31 patients participated and 1 declined. Overall participation among patients was 56%. The top 5 wishes were cloth hearts, blankets, heartbeat printouts, fingerprints and handprints, and music. The total cost was $992, and the average cost per wish was $6.98. Eighty-five percent (33 of 39) of the respondents to the medical team survey indicated that they either agreed or strongly agreed that the project allowed the medical team to consistently provide individualized EOL care.

Conclusions

The survey data support the 3 Wishes Project as a method that allowed the medical team to individualize EOL care and as a valuable tool for incorporation at the bedside.
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines
Authors: Aung Aereas , Irvine Darrell J
Published: January 2024

Primary immune responses following vaccination are initiated in draining lymph nodes, where naive T and B cells encounter Ag and undergo coordinated steps of activation. For humoral immunity, the amount of Ag present over time, its localization to follicles and follicular dendritic cells, and the Ag’s structural state all play important roles in determining the subsequent immune response. Recent studies have shown that multiple elements of vaccine design can impact Ag availability in lymphoid tissues, including the choice of adjuvant, physical form of the immunogen, and dosing kinetics. These vaccine design elements affect the transport of Ag to lymph nodes, Ag’s localization in the tissue, the duration of Ag availability, and the structural integrity of the Ag. In this review, we discuss these findings and their implications for engineering more effective vaccines, particularly for difficult to neutralize pathogens.
THALIDOMIDE AMELIORATES ERYTHROPOIESIS AND IRON HOMEOSTASIS IN TRANSFUSION-DEPENDENT β-THALASSEMIA
Authors: Yang Kun , Xiao Jian
Published: January 2024

Thalidomide is a therapeutic option for patients with β-­thalassemia by increasing fetal hemoglobin and thereby reducing the requirement for blood transfusions. However, information on changes in erythropoiesis and iron homeostasis during thalidomide treatment is lacking. This study investigated the effects of thalidomide treatment on hematologic, erythropoietic, and iron-status parameters in 22 patients with transfusion-dependent β-thalassemia (TDT). Thalidomide significantly improved anemia endpoints, including increases in hemoglobin (p<0.001), red blood cells (p<0.001), and hematocrit (p<0.001), as well as reducing erythropoietin levels (p=0.033) and ameliorating erythropoiesis. Thalidomide treatment significantly reduced serum iron levels (p=0.018) and transferrin saturation (p=0.039) and increased serum transferrin levels (p=0.030). Thalidomide had no observed effect on serum ferritin or hepcidin, but changes in hepcidin(r=0.439, p=0.041) and serum iron (r=−0.536, p=0.010) were significantly correlated with hemoglobin increment. This comprehensive study indicates that thalidomide treatment can ameliorate erythropoiesis and iron homeostasis in patients with TDT, thus supporting the effectiveness of this drug.
CAN WE PREDICT INCIPIENT DIABETES MELLITUS IN PATIENTS WITH TRANSFUSION DEPENDENT β-THALASSEMIA (β-TDT) REFERRED WITH A HISTORY OF PREDIABETES?
Authors: De Sanctis Vincenzo , Soliman Ashraf , Daar Shahina , Tzoulis Ploutarchos , Kattamis Christos
Published: January 2024

Background: Prediabetes and diabetes mellitus (DM) are complications in adult patients with transfusion dependent β-thalassemia (β-TDT), with their incidence increasing with age. Objective: This retrospective observational study describes the glycemic trajectories and evaluates predictive indices of β-cell function and insulin sensitivity/resistance in β-TDT patients with prediabetes, both in a steady state and during 3-h oral glucose tolerance test (OGTT), in order to identify patients at high risk for incipient diabetes. Setting: The study was mainly conducted at the Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara (Italy) in collaboration with thalassemia referring centers across Italy. Patients: The study included 11 β-TDT (aged 15.11- 31.10 years) with history of prediabetes. Methods: The ADA criteria for the diagnosis of glucose dysregulation were adopted. Investigations included evaluation of plasma glucose levels and insulin secretion, analysis of glycemic trajectories and indices of β-cell function and insulin sensitivity/resistance assessed in steady state and during OGTT. Results: The duration of progression from prediabetes to DM, expressed in years, showed a positive direct correlation with corrected insulin response (CIR-30 = r: 0.7606, P: 0.0065), insulinogenic index (IGI 0-120 = r: 0.6121, P:0.045), oral disposition index (oDI = r: 0.7119, P:0.013), insulin growth factor-1 (IGF-1= r: 0.6246, P: 0.039) and an inverse linear correlation with serum ferritin (SF = r: -0.7197, P: 0.012). Conclusions: Progressive β-cell failure, peripheral resistance to the action of insulin and reduction of oDI were the principal factors responsible for the progression from prediabetes to incipient DM.
Seroprevalence of transfusion-transmissible infections among family replacement donors and voluntary non-remunerated blood donors during the COVID-19 pandemic in sub Saharan Africa
Authors: GADJI Macoura , Gueye Youssou Bamar , Motto David , Diop Saliou
Published: January 2024

Introduction : According to WHO,  regular, voluntary, unpaid blood donors are the safest group of donors, as they have the lowest prevalence of blood transmitted infections. However, family/replacement blood donors is widely used in sub Saharan Africa and this practice was exacerbated during the COVID 19 pandemic. This study aimed to compare the seroprevalence of infectious markers in family replacement blood donors and voluntary non-remunerated  blood donors during the COVID 19 pandemic in a country of sub Saharan Africa. 

 Materials and Methods

Blood donors received at the National Centre of Blood Transfusion (NBTC) of Dakar from August 1st to October 31th 2021, were included in this study. All donors completed a pre-donation questionnaire. Donors identity, epidemiological parameters, reasons for donation and laboratory results were collected in the Inlog® software of the NBTC. The serological tests for HBV, HIV and HCV were performed with chemiluminescence technology. The Rapid Plasma Reagent test was used to find out treponemal antibodies. The determination of ABO and Rh blood groups was performed using monoclonal antisera following classical hemagglutination test on a plate.

Results

A total of 5002 donors were collected during this COVID-19 pandemic period. Blood family/replacement donors represented 54.0% and new voluntary donors represented 52.6%. Comparison of HIV, HCV and syphilis markers seroprevalence showed no statistically significant difference between new voluntary donors and new family replacement donors (p>0.05). However, for HBV the seroprevalence was significantly higher in new family replacement donors (p=0,002).

Conclusion

The proper supply of blood was impacted by the COVID-19 pandemic meanwhile replacement donations had contributed to limiting the damage observed with blood shortages. However, the significant differences noted on the seroprevalences of transfusion-transmissible infections between voluntary non-paid donors and family/replacement donors strengthens WHO recommendations for the selection of volunteer non-paid donors to lower transfusion-transmissible HBV in sub Saharan Africa.
CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Authors: Testa Ugo , Sica Simona , Pelosi Elvira , Castelli Germana , Leone Giuseppe
Published: January 2024

Treatment of refractory and relapsed (R/R) B acute lymphoblastic leukemia (B-ALL) is an unmet medical need in both children and adults. Studies carried out in the last two decades have shown that autologous T cells engineered to express a chimeric antigen receptor (CAR-T) represent an effective technique for treating these patients. Antigens expressed on B-cells, such as CD19, CD20, and CD22, represent targets suitable for treating patients with R/R B-ALL. CD19 CAR-T cells induce a high rate (80-90%) of complete remissions in both pediatric and adult R/R B-ALL patients. However, despite this impressive rate of responses, about half of responding patients relapse within 1-2 years after CAR-T cell therapy. Allo-HSCT after CAR-T cell therapy might consolidate the therapeutic efficacy of CAR-T and increase long-term outcomes; however, not all the studies that have adopted allo-HSCT as a consolidative treatment strategy have shown a benefit deriving from transplantation.

For B-ALL patients who relapse early after allo-HSCT or those with insufficient T-cell numbers for an autologous approach, using T cells from the original stem cell donor offers the opportunity for the successful generation of CAR-T cells and for an effective therapeutic approach.

Finally, recent studies have introduced allogeneic CAR-T cells generated from healthy donors or unmatched, which are opportunely manipulated with gene editing to reduce the risk of immunological incompatibility, with promising therapeutic effects.

Keywords: CAR T; Acute Lymphoid Leukemia; Allogeneic CAR-T; Autologous CAR-T.
CAR-T CELL THERAPY FOR FOLLICULAR LYMPHOMAS
Authors: Testa Ugo , D'Alò Francesco , Pelosi Elvira , Castelli Germana , Leone Giuseppe
Published: January 2024

Follicular lymphoma is the second most diagnosed lymphoma in Western Europe. Significant advancements have considerably improved the survival of FL patients. However, 10-20% of these patients are refractory to standard treatments, and most of them will relapse. The treatment of follicular lymphoma patients with multiply relapsed or refractory disease represents an area of high-unmet needing new treatments with stronger efficacy. Chimeric antigen receptor (CAR)-T cell therapy targeting B-cell antigens, such as CD19 or CD20, is emerging as an efficacious treatment for R/R follicular lymphoma patients, particularly for those with early relapse and refractory to alkylating agents and to anti-CD20 monoclonal antibodies, resulting in a high rate of durable responses in a high proportion of patients.
Prof, Bruno Bizzi Obituary
Authors: De Stefano Valerio
Published: January 2024

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Aedes aegypti oviposition in urban communities in the Northern Chihuahuan Desert
Authors: Vera Adam J , Soliz Albert G , de la Mora-Covarrubias Antonio , Watts Douglas M
Published: January 2024

Background & objectives:

Aedes aegypti (Linnaeus) is the vector of multiple arboviruses, the most important being dengue viruses (DENV) that causes more than 90 million cases per year. The expanded range of Ae.
aegypti into temperate climates has contributed to the increasing risk of DENV to new human populations. As an effort to better understand the ecology of Ae. aegypti in a temperate climate, larval surveillance was conducted to identify oviposition locations of this species from 2016-2018 in two nonincorporated communities located in El Paso, Texas and Ciudad Juarez, Chihuahua, Mexico.

Methods:

This survey was conducted inside and outside private residences examining any possible water holding containers to collect with a dipper, turkey baster, or Pasteur pipette. Larvae and pupae were transported to the laboratory and reared to adults for morphological identification. A total of 601 Ae. aegypti larvae were collected and reared to adults from 24 containers in the Sparks community. In contrast, a total of 68 Ae. aegypti were collected and reared to adults from seven containers in the Anapra community.

Results:

In both locations, the predominant container type that yielded immature mosquitoes were plastic buckets. Although the results were based on a small sample size, the finding provided a preliminary understanding of the oviposition sites of Ae. aegypti in two urban communities in a temperate climate region.

Interpretation & conclusion:

The identification of oviposition sites can be used to develop and implement vector control strategies.
The Effectiveness of Training Mothers with regard to Pediculosis Preventive Behavior among School Students; A Protection Motivation Theory Study
Authors: Mohammadpoura Roghayeh , Mohammadbeigib Abolfazl , Gholamrezaee-Sarvelatc Zeynab , Mohebid Siamak , Oskoueie Alireza Omidi
Published: January 2024

Background & objectives:

Today, lice infestation is considered as a reemerging problem as well as a health challenge. Based on Protection Motivation Theory, the present study was conducted to investigate the effectiveness of training mothers in regard to pediculosis preventive behavior among students.

Methods:

In a critical trial, 180 mothers of primary school daughters were assessed in two study groups in the Iranian city of Qom in 2021. They received training intervention in the course of four ninety-minute sessions during four weeks. After six months, the post-test questionnaire and the checklist were completed by them. The data were gathered using a valid and reliable questionnaire. Finally, the data analysis was performed using SPSS 20.

Results:

After the training intervention, a significant difference was observed within the intervention group in scores of the prevention motivation constructs (P<0/001). Besides, there was a significant difference between the mean scores of the preventive behavior of the mothers and daughters in the intervention group before the training intervention and six months after it (P<0/001). However, no significant difference was seen before and after the intervention in the control group (P>0/05). Additionally, no significant differences were observed between the intervention and control groups (P<0/001) in terms of comparing the mean score differences of all the constructs of protection motivation theory, the mothers’ behavior and the daughters’ behavior checklist.

Interpretation & conclusion:

The results indicate the effectiveness of training mothers based on Protection Motivation Theory in regard to pediculosis. Therefore, it seems that in developing training programs, utilizing this theory could prove useful to bring about changes in the individuals’ behavior regarding the prevention of pediculosis.
Spatiotemporal, demographic, and climatic drivers of malaria transmission in the endemic setting of Jazan, Saudi Arabia: A retrospective study
Authors: Alqassim Ahmad Y
Published: January 2024

Background & objectives:

Despite progress, malaria remains endemic in Jazan, Saudi Arabia necessitating epidemiological research to guide elimination strategies. This study analyzed recent surveillance data to elucidate drivers of sustained transmission. A retrospective epidemiological study was conducted using malaria surveillance data from the Jazan region of Saudi Arabia over a 3-year period from January 2018 to December 2020.

Methods:

Deidentified records of all confirmed malaria cases reported across Jazan during the study period were obtained from Jazan Department of Health infectious disease surveillance system. Additional meteorological data was acquired to assess climatic correlates. The final analysis included 5255 confirmed cases that met the completeness criteria for key variables. Descriptive statistics characterized cases across demographic factors and spatial and temporal distributions. Correlations and linear regression modeling identified associations between monthly cases and weather parameters mapping visualized geographic patterns.

Results:

Of the 5255 confirmed cases, most were concentrated in Baish sector (50.8-72.0% annually), affected adult male foreigners (93.8-97.0%), peaked inconsistently across seasons, and were imported (85.4-94.9%). Non-Saudi nationalities had 6-fold higher incidence versus Saudi citizens in 2020 (677.6 vs 23.1 per 100,000). Monthly cases associated negatively with temperature (p=0.015) and positively with windspeed (p=0.005).

Interpretation & conclusion:

Malaria persistence in Jazan involves geographic and demographic hotspots driven by imported infections and climate effects on vectors. Tailored programming aligned with evolving local dynamics will be essential to sustain elimination gains. Surveillance, optimized interventions, and flexible adaptation to high-risk locations and/or populations and meteorological influences are key priorities.
Perspective of Undergraduate Health-care Students on Adverse Drug Reaction and Pharmacovigilance
Authors: Atia Ahmed , Abdulwahed Eman
Published: January 2024

Background:

Pharmacovigilance (PV) is a crucial field of study everywhere. However, there is a serious knowledge gap regarding PV and adverse drug reactions (ADRs) reporting among health-care students. The aim of this study was to evaluate Libyan health-care students’ understanding of PV and reporting of ADRs.

Methods:

This was a cross-sectional questionnaire-based study conducted among 204 undergraduate health-care students from different universities in Tripoli. The participants’ knowledge and perceptions regarding PV and ADRs reporting were evaluated using a validated structured questionnaire that had undergone pilot testing. Descriptive statistics were used to describe the study findings.

Results:

There was poor knowledge of PV and ADRs reporting among surveyed students. Students’ perception outweighed their knowledge, with pharmacy students scoring the highest among all health-care students. The overall awareness and knowledge’s score ranged from 13.2% to 89.2%.

Conclusion:

Integration of PV concepts in the education curriculum, and training of pharmacists in ADRs reporting is very crucial in achieving better drug safety.
Complete Chloroplast Genome of Endangered Bruguiera hainesii C.G.Rogers 1919 and Phylogenetic Analysis with Associated Species
Authors: Tran Viet Ha , Hoang Thi Thu Trang , Pham Mai Phuong , Vu Dinh Giap , Nguyen Quoc Khanh , Vu Dinh Duy
Published: January 2024

Background:

Bruguiera hainesiiC.G. Rogers 1919, a true mangrove tree is a critically endangered species (CR) in Vietnam. This species is restricted to the Con Dao National Park, Ba Ria-Vung Tau province, where it occurs in very tiny populations. However, the exploration of the chloroplast genome ofB. hainesiiin Vietnam has a serious lack of information. It is extremely challenging to promote the conservation ofB. hainesii. Therefore, urgently required to discover and comprehend the chloroplast genome ofB. hainesii.

Methods:

To detect evolutionary analysis between mangroves, we sequenced the complete chloroplast genome ofB. hainesiiusing next-generation sequencing technology (Illumina Hiseq X Ten).

Results:

We sequenced and assembled the complete chloroplast genome ofB. hainesii, which was deposited in GenBank as accession number OR086085. The DNA was circular with 164,305 bp length, comprising 37% GC. The genome contained a large single-copy region of 91,724 bp, inverted repeat regions of 26,360 bp, and a short single-copy region of 19,861 bp. Furthermore, it contained 130 genes, consisting of 83 protein-coding genes, 37tRNAs, and 8rRNAs. We detected 131 single-sequence repeats, including 119 mononucleotides, 11 dinucleotides, and one trinucleotide. Phylogenetic analysis showed strong support thatB. hainesiiwas sister toB. cylindrica.

Conclusions:

The findings in this study provide a foundation for species identification, evolutionary genetics, and the conservation of endangeredB. hainesiiin Vietnam.
Bird's-eye view of prevalence, mechanism of injury, and prevention of sports-related orofacial injuries in basketball game
Authors: Joshi Riddhi , Kshirsagar Krutarth
Published: January 2024

Sports-associated orofacial trauma causes negative sequelae in an athlete. To prevent this, we must closely assess the mechanism as well as the available literature regarding the prevalence. It is easier to apply knowledge of sports dentistry if the injury mechanism, types of injury, and management are known. Every single game is accompanied by its own set of injuries. Basketball is a dynamic game. Athletes involved in this game are at high risk of orofacial injuries. The preventive aspect is often a blind spot, especially in Indian Sports. This review gives a bird's-eye view of the type of orofacial trauma and prevention in athletes playing basketball game.
Awake tracheal extubation, can be anticipated? case reports
Authors: Aljonaieh Khalid
Published: January 2024

Perioperative airway management is a crucial task for anesthesiologists. Several perioperatively techniques make it difficult to predict the appropriate time for tracheal extubation. The aim of this article is to report the successful anticipation of an appropriate time for awake tracheal extubation. Three cases were observed related to smooth recovery without airway complication following intentionally removing airway devices after specific time. These reports demonstrate the relationship between awake status and return of spontaneous breathing which may demonstrate a good recovery of different sites of central nervous system from anesthesia effects. Theoretically, the appropriate time for awake tracheal extubation can be anticipated.
Drone a technological leap in health care delivery in distant and remote inaccessible areas: A narrative review
Authors: Sharma Sanjana , Sharma Hunny
Published: January 2024

In developing countries, last-mile delivery of medical products is a challenge, especially in hilly and rural areas where there is no road connectivity. As helicopters or other air services are not affordable all the time, drones can be used for the supply of medical products. They are cost-effective as compared to other air or road transport. However, the carrying capacity of drone is less, it is not able to carry heavier payloads. Also, operating drones requires trained operators, and it is a new venture in a developing country so possibilities of confusion and lack of clarity on operating procedures are there. Drones are becoming increasingly reliable for the health care delivery. This narrative review explores the use of drones in healthcare delivery globally.
STROBE, CONSORT, PRISMA, MOOSE, STARD, SPIRIT, and other guidelines – Overview and application
Authors: Grech Victor , Eldawlatly Abdelazeem A.
Published: January 2024

The purpose of research is to seek answers and new knowledge. When conducted properly and systematically, research adds to humanity's corpus of knowledge and hence to our general advancement. However, this is only possible if reported research is accurate and transparent. Guidelines for all the major types of studies (STROBE, CONSORT, PRISMA, MOOSE, STARD, and SPIRIT) have been developed and refined over the years, and their inception, development, and application are briefly discussed in this paper. Indeed, there are currently over 250 of these guidelines for various types of medical research, and these are published by the EQUATOR network. This paper will also briefly review progress in acceptance and adoption of these guidelines.
A complex case of posterior reversible encephalopathy syndrome after combined spinal epidural of preeclampsia parturient: A case report
Authors: Heo Min Hee , Choi Hwan Yong , Lee Kwanghyuk , Kim Ji Yeon
Published: January 2024

Posterior reversible encephalopathy syndrome (PRES) is a disorder characterized by vasogenic edema affecting the posterior brain region. We report a case of PRES in a 36-year-old woman with preeclampsia who underwent an emergency cesarean section with spinal anesthesia. After surgery, she developed right leg weakness, headache, and seizures. Imaging showed white matter edema consistent with PRES. The exact cause of PRES is unclear, but elevated blood pressure and endothelial dysfunction are implicated. Tight blood pressure control in PRES is crucial for management, and prompt recognition and treatment are essential for favorable outcomes.
Postmortem Redistribution of Lidocaine after Illegal Use
Authors: Attafi Ibraheem M. , Oraiby Magbool E. , Albeishy Mohammed Y. , Fageeh Mohsen M.
Published: January 2024

Lidocaine is the most common local anesthetics used for para cervical block to reduce pain associated with surgical abortion. Topical form of lidocaine and its contents have been used for illicit purposes and suicidal intentions. We present two case reports of lidocaine-related death. All samples were extracted using solid phase extraction and lidocaine was identified and quantified by gas chromatography with mass spectrometry. Lidocaine concentrations were detected all analyzed samples with lethal levels. Toxicological findings and factors affecting lidocaine postmortem redistribution and results interpretation are discussed.
A Rare Case of Fatal Lightning Strike in Dammam with Unusual Cutaneous Findings
Authors: Kharoshah Magdy , Alsaif Dalia Mohammed , Albouijan Abdullah , Almoghannam Salah
Published: January 2024

Determining the cause of death in lightning strikes could be easily reached if the circumstances were witnessed or if typical kerauno-pathologic features were found on the body. However, in rare cases, certain unusual skin features are found, which makes attribution to the cause of death more difficult, especially if unwitnessed. In this case, a witnessed lightning strokes a 42-year-old male while he was walking outdoors in a rainy day, leaving him with a rare finding of punctuate burns over the back of the body (crocodile skin) and nonspecific internal organ findings. The clothes were burnt and shredded, and the hair of the affected area was singed. Rare findings of lightning strikes need to be reported as they can be the key in leading investigations in unwitnessed strikes.
TÜRKİYE’DE ÖZEL SEKTÖR HUZUREVLERİ İÇİN BÖLGELERARASI EŞİTSİZLİK ANALİZİ
Authors: ÇİFTÇİ Murat
Published: January 2024

Dünya genelinde yaşlı bakımında huzurevleri, her geçen gün önemini arttırmaktadır. Özellikle son yıllarda Türkiye’de de değişen aile yapısı, ekonomik koşullar ve devlet destekleriyle huzurevlerinde hızlı bir gelişim yaşanmaktadır. Artan yatak arzı, toplumdan da karşılık bularak daha çok yaşlının huzurevlerinin ikamet alanına dönüşümünü beraberinde getirmiştir. Bu çalışmada özel huzurevlerindeki yatak arzının 60+ yaştaki nüfusa göre bölgelerarası dağılımları analiz edilmiştir. İstatistik analizler Atkinson eşitsizlik katsayılarının hesaplanmasıyla gerçekleştirilmiştir. Eşitsizlik şiddetinin tespiti için özel sektör huzurevlerinin yanı sıra kamu kesimi huzurevlerindeki yatak arzının da 60+ yaştaki nüfusa göre bölgelerarası dağılımında Atkinson eşitsizlik katsayıları hesaplanmıştır. Ayrıca Atkinon eşitsizlik katsayısına dayanarak sosyal fayda oranı, sosyal fayda kaybı oranı, yaşlılarca hissedilen yatak sayısı, yaşlılarca hissedilmeyen yatak sayısı da hesaplanmıştır. Veriler en güncel detaylı huzurevi yatak sayılarının sunulduğu 2019 yılına aittir. Uygulama NUTS 2’ye göre yapılmış, ancak 26 alt bölgeden 14’ünde özel huzurevi olduğundan, 14 alt bölge kapsanmıştır. Ancak 14 alt bölge de yaşlı nüfusun yaş dilimleri içerisinde %70-75’i arasında geniş bir kesimi kapsamıştır. Elde edilen bulgular hem faal olarak kullanılan yatak sayısının, hem de yatak kapasitesinin dokuz farklı yaşlı yaş dilimine göre ve kadın, erkek, toplam olarak bölgelerarası dağılımında, özel huzurevlerinde kamu kesimi huzurevlerindekine göre çok şiddetli dengesiz dağılımın yaşandığını göstermektedir.
Análisis de la calidad y el desarrollo de instituciones de educación superior en México.
Authors: Ángeles Guzmán Casandra , De Escobar Fernández Arturo Martínez , Surdez Pérez Edith Georgina
Published: January 2024

La investigación tiene como objetivo analizar el desarrollo institucional y la calidad educativa de las instituciones de educación superior (IES) públicas en México que aplican planificación estratégica. La metodología empleada consiste en una revisión bibliográfica de tipo documental en materiales electrónicos durante los últimos cinco años (2019-2023). Con base en la teoría, se considera que el desarrollo institucional y la calidad educativa se ven reflejadas en el crecimiento de la matrícula escolar a través del tiempo, ya que una planificación estratégica exitosa radica en el logro de los objetivos y metas organizacionales en dónde se destaca la consolidación y el prestigio de las instituciones de educación superior (IES) públicas.
Investigación estética a través del dibujo como herramienta para el desarrollo del pensamiento complejo en los estudiantes universitarios de arte.
Authors: Quispe Fernández Gregorio
Published: January 2024

La investigación estética a través del dibujo es una propuesta educativa que busca promover el desarrollo del pensamiento complejo en los estudiantes universitarios de arte. El dibujo es una herramienta que permite a los estudiantes explorar formas de representar el mundo, lo que les ayuda a desarrollar habilidades cognitivas, emocionales y sociales. El pensamiento complejo es una forma de pensamiento que integra diferentes perspectivas, es crítico y creativo, y resuelve problemas de forma innovadora. Estas habilidades son fundamentales para el desarrollo integral de los estudiantes y para su participación en sociedad. Se concluye que el dibujo es una herramienta que favorece el pensamiento complejo en los estudiantes, brindándoles un espacio de libertad, experimentación y diálogo.
Perspectiva de coordinadores de carrera ante la pandemia COVID-19 en la educación universitaria.
Authors: Molina Gutiérrez Teresa de Jesús , Infante Miranda María Elena , Chugá Quemac Rosa Evelyn
Published: January 2024

La gestión directiva en el ámbito universitario desempeña un papel crítico en la consecución de los objetivos institucionales, especialmente en situaciones excepcionales como la pandemia de COVID-19. Este estudio se enfocó en la percepción de los coordinadores de carrera de tres universidades privadas respecto a las decisiones, supervisión y evaluación de su impacto en las actividades académicas durante la pandemia. Utilizando el enfoque socio-crítico y una metodología de investigación participante, se entrevistó a 12 docentes-coordinadores de carrera. Los resultados revelaron que estos coordinadores, a pesar de su función de supervisión, se consideran empleados de nivel medio y tienden a atribuir la responsabilidad de los resultados del proceso educativo a otros funcionarios. Sin embargo, se reconoce su esfuerzo por adaptarse y diseñar estrategias para abordar las circunstancias de emergencia.
Conceptualización y análisis reflexivo sobre la enseñanza por competencias en nivel superior.
Authors: Camacho-Javier Minerva , López Del Castillo José César , Camacho Javier Deyanira
Published: January 2024

En la investigación educativa, es fundamental reflexionar constantemente sobre las competencias del profesorado universitario con el fin de mejorar el proceso de enseñanza-aprendizaje. En este estudio, se analizaron los constructos de competencia y competencias transversales, y la complejidad que implican en la actuación del profesorado universitario; para ello, se realizó una revisión sistemática de artículos, complementada con una base de datos de una investigación previa. Se reconoce que las competencias transversales son complejas en el contexto de la enseñanza-aprendizaje y desempeñan un papel importante en la atención que el profesorado presta durante el proceso educativo; además, se ha evidenciado, que en muchas ocasiones, la capacidad interpretativa y crítica se ve afectada por patrones actitudinales no conscientes.
Apoyo docente y paterno en el impulso femenino por carreras STEM. Validación psicométrica de una escala.
Authors: Magaña Medina Deneb Elí , Aguilar Morales Norma , Hernández Mena Verónica
Published: January 2024

El papel de los padres y profesores es relevante en el impulso de las mujeres para la selección de carreras STEM. El objetivo del estudio fue la determinación de las propiedades psicométricas de una escala de medición para la estimación de las perspectivas de las estudiantes sobre el apoyo de padres y profesores en el fomento por carreras en ciencia, tecnología, ingeniería o matemáticas en instituciones de educación media superior en zonas rurales. Se desarrolló un análisis factorial exploratorio y confirmatorio, y se estimaron los principales indicadores de fiabilidad y validez. Se concluye que el modelo propuesto cumple con los atributos psicométricos necesarios para ser empleado en el estudio de este fenómeno en el contexto para el cual fue desarrollado.
Efectos de la utilización de las tecnologías de información y comunicación en el mundo moderno.
Authors: Torres Merlo Oswaldo Xavier , Yancha Villacis Mario Marcelo , Ramírez Rodríguez Beatriz Elizabeth
Published: January 2024

Esta investigación tuvo como objetivo analizar las implicaciones del uso de las TIC en la población de Ibarra, Ecuador, a través de una metodología mixta y descriptiva. Los resultados revelaron que una parte significativa de los encuestados dedica gran parte de su tiempo diario al uso de dispositivos electrónicos, principalmente para actividades laborales y educativas. Además, se destacó un mayor conocimiento y competencia en el uso de redes sociales en comparación con paquetes de software de oficina. En resumen, las TIC han transformado la forma en que las personas se comunican, trabajan y aprenden, ofreciendo beneficios sustanciales, pero también planteando desafíos cuando se utilizan inadecuadamente.
Impacto de las Tecnologías de la Información y Comunicación (TIC) en los centros culturales: análisis comparativo.
Authors: Castillo Méndez Rocío del Carmen , Aguirre Andrade Antonio , De Dios Domínguez Wilber
Published: January 2024

Este artículo científico analiza el impacto de las Tecnologías de la Información y Comunicación (TIC) en centros culturales mediante un análisis comparativo. Se enfoca en centros culturales en Cárdenas y Villahermosa, Tabasco, evaluando el uso de las TIC en la promoción de actividades culturales. El estudio descriptivo y exploratorio emplea fuentes web y opiniones de coordinadores y usuarios de talleres culturales. Aunque se observa un uso limitado de las TIC, se destaca el beneficio derivado del empleo frecuente de Facebook como red social en ambos centros. Este análisis busca comprender cómo las TIC influyen en la difusión de actividades culturales y su potencial para aumentar la afluencia de visitantes a estos recintos.
Transformación digital y gestión financiera en la administración hospitalaria en una institución pública de salud, 2023.
Authors: Cuba Diaz Alexander Edward , Cardenas Condori Carmen Rosa
Published: January 2024

El artículo analiza cómo la integración de tecnologías digitales y la optimización de los procesos financieros impactan en la gestión de los hospitales públicos. La transformación digital en la administración hospitalaria implica la implementación de sistemas electrónicos de registro médico, soluciones de telemedicina y análisis de datos, lo que mejora la calidad de la atención al paciente y respalda la toma de decisiones informadas. La gestión financiera efectiva se logra mediante la automatización de procesos financieros, como contabilidad, facturación, gestión de inventarios y administración de presupuestos. La transformación digital y la gestión financiera en la administración hospitalaria también promueven la transparencia y la rendición de cuentas, al registrar y documentar todas las transacciones financieras, facilitando auditorías internas y externas.
Comprensión de las regulaciones contractuales públicas entre emprendedores de la Terminal Terrestre en Babahoyo: un análisis profundo.
Authors: Troya Terranova Katherine Tatiana , Mariscal Rosado Zoila Mirella , Cherrez Cherrez David Daniel
Published: January 2024

Este estudio se centra en evaluar el nivel de conocimiento de normativas públicas con las que cuentan los emprendedores ubicados en la terminal terrestre de la ciudad de Babahoyo. El objetivo es analizar cómo estas normativas afectan la formalidad legal de los negocios y las relaciones comerciales. El trabajo adopta un enfoque de investigación-acción y utiliza métodos narrativos y encuestas para recopilar y analizar datos. La población de estudio se encuentra en el terminal terrestre de Babahoyo, y se emplea un muestreo aleatorio estratificado, utilizando medios digitales para encuestas y entrevistas con egresados y docentes de la institución. Los resultados se orientan a comprender la percepción y conocimiento de las normativas contractuales entre los emprendedores locales.
La administración pública bajo la perspectiva de la gobernanza y sus principios.
Authors: Piray Rodríguez Paúl Orlando , Rosero Parra David Sebastián , Silva Andrade Guido Javier , Narváez Inca Gisella Carolina
Published: January 2024

En Ecuador, la ausencia de institucionalización en los órganos estatales y empresas públicas obstaculiza la efectividad de las políticas públicas, reguladas por la Ley Orgánica del Servicio Público, y su aplicación en una gobernanza efectiva demanda el análisis y cumplimiento de estos principios. La investigación aborda críticamente la vigencia y aplicación de la legalidad, eficiencia, buena administración y proporcionalidad en la gobernanza administrativa ecuatoriana. A través de un enfoque documental, basado en normativas constitucionales y jurisprudencia, se pretende comprender los desafíos y limitaciones en su aplicación, con el objetivo de contribuir al debate y proponer mejoras para una administración pública más eficaz.
Análisis de la hipersexualización de menores derivada del tipo de contenidos presentes en los medios de comunicación a gran escala.
Authors: Espinoza Lastra Oscar Roberto , Suárez Espinosa Evelyn Elizabeth , Alarcón López Fanny Monserrath
Published: January 2024

La inquietud contemporánea sobre la hipersexualización de niños y niñas se intensifica dado el creciente acceso de los menores a información estereotipada a través de los medios de comunicación masiva. Este estudio, arraigado en marcos teóricos pertinentes, orientó un análisis de campo para evaluar la percepción y aceptación de padres frente a manifestaciones de hipersexualización en menores. Se desarrollaron instrumentos de recolección de datos y se aplicaron encuestas a padres con hijos entre 7 y 12 años en la ciudad del Puyo. Los resultados sugieren un aumento gradual de la hipersexualización en niños y niñas, impulsado por la constante influencia de los medios de comunicación masiva.
Evaluación psiquiátrica de menores infractores involucrados en el delito de sicariato.
Authors: Rey Suquilanda Cristoval Fernando , Gallegos Gallegos Simón Bolívar , Robalino Villafuerte José Luis , Espín Canga Lenin Hermógenes
Published: January 2024

La investigación se centra en los adolescentes infractores y su relación con posibles alteraciones del sistema nervioso central. El objetivo del estudio es analizar la importancia de la pericia psiquiátrica en adolescentes involucrados en el delito de sicariato, considerando el principio del interés superior del niño en Ecuador. Se emplea un enfoque de investigación mixto con métodos cualitativos y cuantitativos, destacando que los factores exógenos tienen un fuerte impacto en el desarrollo de trastornos mentales en adolescentes infractores. Como resultado, se sugiere la necesidad de realizar pericias psiquiátricas para evaluar su estado mental y tomar medidas adecuadas tanto desde una perspectiva médica como en términos de reintegración social.
Análisis de las bases para las decisiones sancionatorias de la policía nacional: un enfoque en el cantón Santo Domingo.
Authors: Santillán Andrade Julián Rodolfo , Álava Vega Josselyn Roxana , Maldonado Cando José Luis , Nevárez Moncayo Juan Carlos
Published: January 2024

El principio de motivación es crucial en el debido proceso legal, particularmente en procedimientos disciplinarios de la Policía Nacional. La investigación busca evaluar el cumplimiento del principio de motivación en las resoluciones sancionatorias de la Policía Nacional, empleando un enfoque mixto que combina análisis documentales con datos de campo. El resultado principal se basa en el análisis de casos judiciales relacionados con acciones legales de protección, que han revelado incumplimientos del debido proceso, especialmente en la motivación de las decisiones disciplinarias. En resumen, se enfatiza la necesidad de capacitación continua en áreas legales para las autoridades encargadas de los procesos disciplinarios en la Policía Nacional, garantizando así la aplicación justa y fundamentada de la ley.
Análisis jurídico comparativo del derecho a la desconexión digital laboral en Ecuador.
Authors: Valverde Torres Yanhet Lucía , Andrade Salazar Oswaldo Liber , Quevedo Arnaiz Ned Vito , García Arias Nemis
Published: January 2024

La investigación se enfoca en el derecho a la desconexión digital en el ámbito laboral, permitiendo a los trabajadores decidir si responder a las solicitudes de sus empleadores fuera del horario laboral sin sanciones. Se analiza la normativa laboral nacional e internacional, utilizando métodos de investigación como análisis-síntesis y el enfoque exegético, destacándose la divergencia entre países europeos y latinoamericanos, siendo Francia y España ejemplos de regulaciones previas a la pandemia de COVID-19 que benefician a todos los trabajadores, incluso los directivos. En contraste, Ecuador y otros países latinoamericanos limitan este derecho a los trabajadores de teletrabajo. Se enfatiza en aprender de la experiencia europea para armonizar regulaciones laborales en América Latina.
Un estudio jurídico de las criptomonedas en el marco de la protección de los derechos legales.
Authors: Puetate Paucar Jairo Mauricio , Coka Flores Diego Fernando , Portilla Paguay Rene Estalin
Published: January 2024

Este estudio analiza la regulación de las criptomonedas en Ecuador, especialmente en la Ley de Mercado de Valores, con el objetivo de asegurar el respeto al derecho de seguridad jurídica establecido en la Constitución ecuatoriana. El estudio resalta elementos esenciales de las criptomonedas, su naturaleza, riesgos, beneficios, importancia en el contexto legal ecuatoriano y su falta de regulación específica en Ecuador a través de métodos de investigación cualitativa. Se plantea la necesidad de promulgar una normativa legal que las incluya en la Ley de Mercado de Valores y otras leyes pertinentes. Se concluye con hallazgos clave y perspectivas para la toma de decisiones y políticas relacionadas con la regulación de las criptomonedas en Ecuador.
Protección de los derechos humanos de los beneficiarios del consultorio jurídico UNIANDES Quevedo en tiempos de la pandemia por COVID-19.
Authors: Gaspar Santos Manaces Esaud , Triviño Vera Karen Clemencia , Zambrano Olvera Marcela Anarcaly
Published: January 2024

Esta investigación se enfoca en proteger y defender los derechos humanos de quienes tienen necesidades prioritarias. Esta necesidad de investigación surge del estado de excepción decretado por el Gobierno durante la pandemia, que restringió la movilidad de las personas. El estudio utiliza un diseño de investigación mixto y longitudinal, que combina métodos cualitativos y cuantitativos. Se recopilaron datos a través de entrevistas semiestructuradas en campo, lo que permitió identificar denuncias de usuarios insatisfechos con la violación de sus derechos; además, se proporcionó orientación a los usuarios en las consultas virtuales sobre las medidas para prevenir violaciones a sus derechos fundamentales.
El procedimiento abreviado: ¿Una salvaguarda para el delincuente o un riesgo para la seguridad ciudadana?
Authors: Andrade Santamaría Danilo Rafael , Cisneros Zúñiga Cinthya Paulina , Jiménez Martínez Roberto Carlos , Miranda Chávez Luis Rodrigo
Published: January 2024

La institución del Procedimiento Abreviado, establecida en Ecuador desde 2014 mediante el Código Orgánico Integral Penal, constituye un tema de análisis crucial. Esta investigación se centrará en aspectos teóricos del Procedimiento Abreviado, evaluando su naturaleza como garantía legal y constitucional para los delincuentes o como un riesgo inconstitucional para la seguridad ciudadana. Se examinará la posibilidad de restringir este recurso en todos los delitos en respuesta a la actual inseguridad en Ecuador. Adoptando un enfoque cualitativo y descriptivo, se explorarán los requisitos y su aplicabilidad en diversos delitos. El objetivo final es comprender la relevancia del Procedimiento Abreviado y determinar si realmente beneficia a la sociedad ecuatoriana.