bluuebunny/crossref_metadata_2025 huggingface dataset:
Fosinopril inhibits Ang II-induced VSMC proliferation, phenotype transformation, migration, and oxidative stress through the TGF-β1/Smad signaling pathway
Authors: Chen Siqi , Ye Lingxiang
Published: November 2024

Fosinopril (FOS) is an angiotensin-converting enzyme inhibitor that can decrease angiotensin II (Ang II) formation, thereby reducing systemic vasoconstriction. This study investigated the impact of FOS on vascular smooth muscle cell (VSMC) phenotypic transformation in hypertension. Experiments using western blotting revealed that FOS inhibits the Ang II-induced downregulation of α-SMA and SM22α and the upregulation of OPN in VSMCs. In addition, CCK8 assays, EdU staining, and Transwell assays demonstrated that FOS reduces Ang II-induced increases in VSMC cell viability, proliferation, migration, and MMP2 and MMP9 expression. Moreover, immunofluorescence and ELISA experiments showed that FOS suppresses Ang II-induced increases in ROS levels, NAD(P)H activity, and NOX2 and NOX4 expression in VSMCs. Western blotting also indicated that FOS inhibits Ang II-induced increases in TGF-β1 and p-Smad2/3 expression in VSMCs. Finally, FOS mitigates Ang II-induced VSMC proliferation, phenotypic transformation, migration, and oxidative stress by inhibiting the TGF-β1/Smad signaling pathway. In conclusion, these results suggest that FOS could be effective in managing vascular diseases, including hypertension.
Review: Dicranostigma leptopodum: A peculiar plant of Papaveraceae
Authors: Tian Ye , Geng Yang , Zhang Yaolei , Zhao Zeyue , Ruan Lihong , Zhang Chuanbao
Published: November 2024

Dicranostigma leptopodum (Maxim.) Fedde, an intriguing plant of the Papaveraceae family, exhibits numerous physiological activities, including antitumor, cytotoxic, immune-boosting, antibacterial, antioxidant, insecticidal, smooth muscle modulation, antiarrhythmic, fluorescent probe capabilities, as well as hypolipidemic and hypoglycemic effects. The plant’s diverse pharmacological actions are believed to be attributed to its rich reservoir of alkaloids distributed throughout the entire plant. This review encompasses an exploration of the chemical constituents, pharmacological activities, species distribution, extraction and separation methodologies, and content determination of D. leptopodum, aiming to contribute to its further advancement in medicinal development.
Renal microangiopathy and immune complex glomerulonephritis induced by anti-tumour agents: A case report
Authors: Guo Li , Hao Zhen-Zhen , Zhang Qian , Liu Qiu-Ju , Gao Yan , Ran Lei
Published: November 2024

A 60-year-old woman with bilateral lower extremity oedema for several days was admitted to the hospital on 21 November 2023. Previously, after receiving rectal cancer resection in February 2023, she had been receiving drug chemotherapy, during which she had normal urinalysis and renal function. However, 10 days before admission, after the drug regimen was adjusted to tislelizumab + fruquintinib, she developed bilateral lower extremity oedema with foamy urine; this was later extended to facial oedema. After a histologic examination of renal biopsy, it was judged as drug-induced glomerular microangiopathy (GMA) with focal segmental glomerulosclerosis-like lesions accompanied by immune complex-mediated glomerulonephritis. The condition was controlled by stopping the anti-tumour drug, lowering glucose with linagliptin, and providing renal protection with Nephritis Rehabilitation Tablets, and the patient recovered well at the follow-up visit after 6 months. This case may be GMA induced by tislelizumab or fruquintinib and was examined in this study.
The fourth moment of the Hurwitz zeta function
Authors: Heap Winston , Sahay Anurag
Published: November 2024

We prove a sharp upper bound for the fourth moment of the Hurwitz zeta function

ζ
⁢

(
s
,
α
)

\zeta(s,\alpha)

on the critical line when the shift parameter 𝛼 is irrational and of irrationality exponent strictly less than 3.
As a consequence, we determine the order of magnitude of the

2
⁢
k

2k

th moment for all

0
⩽
k
⩽
2

0\leqslant k\leqslant 2

in this case.
In contrast to the Riemann zeta function and other 𝐿-functions from arithmetic, these grow like

T
⁢

(

log
⁡
T

)

k

T(\log T)^{k}

.
This suggests, and we conjecture, that the value distribution of

ζ
⁢

(
s
,
α
)

\zeta(s,\alpha)

on the critical line is Gaussian.
Existence of three solutions for two quasilinear Laplacian systems on graphs
Authors: Pang Yan , Zhang Xingyong
Published: November 2024

We deal with the existence of three distinct solutions for a poly-Laplacian system with a parameter on finite graphs and a

(

p
,
q

)

\left(p,q)

-Laplacian system with a parameter on locally finite graphs. The main tool is an abstract critical point theorem in [G. Bonanno and S. A. Marano, On the structure of the critical set of non-differentiable functions with a weak compactness condition, Appl. Anal. 89 (2010), no. 1, 1–10]. A key point in this study is that we overcome the difficulty to prove that the Gâteaux derivative of the variational functional for poly-Laplacian operator admits a continuous inverse, which is caused by the special definition of the poly-Laplacian operator on graph and mutual coupling of two variables in system.
A data augmentation approach to enhance breast cancer detection using generative adversarial and artificial neural networks
Authors: Alawee Wissam H. , Al-Haddad Luttfi A. , Basem Ali , Al-Haddad Abdullah A.
Published: November 2024

Breast cancer is globally known to be a major health concern that necessitates advancements in detection and classification methods. This study introduces a machine learning-based approach for breast cancer diagnosis using benign and malignant mammograms of breast cancer. A two-hidden-layer artificial neural network (ANN) model was designed to categorize breast cancer from mammographic images. Prior to analysis, the images were subjected to a sophisticated data augmentation process that leveraged data denoising, contrast enhancement, and the application of a generative adversarial network (GAN). This multi-enhancement preprocessing enriched the quality of the images and transformed them into a format more amenable to analysis by vectorizing the pixel data. The methodology involved rigorous training of the ANN on input images, resulting in a significant improvement in the model’s ability to classify breast cancer accurately. Experimental results demonstrate a notable enhancement in classification performance, with an increase in accuracy ranging from 22.5 to 42.5% compared to traditional scans. The final model achieved an impressive accuracy rate of unity, which considered all stages of image processing, including normal, contrast-enhanced, denoised, and GAN-enhanced scans. The outcomes of this research underlined the effectiveness of data augmentation and ANN in medical imaging. Future innovations in breast cancer diagnostics are elaborated by the potential to improve early detection and patient outcomes. The robust offered methodology for breast cancer detection is considered to be a significant contribution to biotechnological fields of interest.
Rhus microphylla-mediated biosynthesis of copper oxide nanoparticles for enhanced antibacterial and antibiofilm efficacy
Authors: Al Musayeib Nawal M. , Amina Musarat , Al-Yousef Hanan M. , Haq Mohsin ul , Al-Daihan Sooad , Bhat Ramesa Shafi
Published: November 2024

The global emergence and tenacity of multidrug-resistant microbes have raised new challenges for the management of diseases associated with infections. Metal-based nanoparticles (NPs) have recently received special attention as a prospective alternate for existing chemical antibiotics because of their extensive antibacterial potency and low toxicity. Herein, copper nanoparticles (CuONPs) were prepared by using an aqueous extract of aerial parts Rhus microphylla (RM) aerial parts. The obtained RM-CuONPs were characterized and evaluated for antimicrobial and antibiofilm potential against various human pathogens. The formed RM-CuONPs were well dispersed with a uniform spherical shape and an average size of 32.45 nm. Numerous functional moieties found in the FTIR spectra confirmed that the phytocomponents of the RM-extract were in charge of the synthesis synthesis, capping, and stabilization of RM-CuONPs. The biogenic RM-CuONPs demonstrated superior antibacterial effectiveness towards Staphylococcus epidermidis and Enterobacter cloacae with a minimum inhibitory concentration (MIC) value of 48.5 µg·mL−1. Remarkable antifungal activity of RM-CuONPs was noted against C. tropicalis (MIC = 97 µg·mL−1). Also, the biosynthesized RM-CuONPs demonstrated notable potential in reducing biofilm formation in a dose-dependent manner. These inferences offer an insight into the plausible for utilizing plant extracts for the biosynthesis of CuONPs with enhanced biological activity and could offer promising effective substitutes to traditional antimicrobials for the treatment of biofilms and drug-resistant bacteria.
Harnessing trichalcogenide–molybdenum(vi) sulfide and molybdenum(vi) oxide within poly(1-amino-2-mercaptobenzene) frameworks as a photocathode for sustainable green hydrogen production from seawater without sacrificial agents
Authors: Aldosari Eman , Rabia Mohamed , Moussa Mahmoud , Abdelazeez Ahmed Adel A. , Elsayed Asmaa M.
Published: November 2024

This research focuses on converting Red Sea seawater into environmentally friendly hydrogen (H2) gas by developing an innovative photocathode termed MoS3–MoO3/PA2MB. Fabricated through a single-step process, this photocathode demonstrates impressive performance, achieving an H2 production rate of 6.0 µmol/10 cm²·h with a current density (J
ph) of −0.7 mA·cm⁻². The effectiveness of this photocathode is highlighted by its favorable morphological properties, characterized by semi-spherical shapes measuring 130 nm in width and 170 nm in length. Moreover, the MoS3–MoO3/PA2MB photocathode exhibits excellent light absorbance across a wide spectrum, benefiting from a small bandgap of 1.6 eV, which significantly enhances its efficiency in converting light energy into hydrogen gas. The photocathode’s performance is rigorously tested under various optical conditions, with photon energies ranging from 3.6 to 1.7 eV. As the photon energies decrease from 3.6 to 1.7 eV, the J
ph values decrease from −0.53 to −0.43 mA·cm⁻², demonstrating the photocathode’s adaptability to different optical environments. Overall, the successful synthesis of the MoS3–MoO3/PA2MB photocathode marks a significant advancement in H2 gas production directly from seawater. This technology shows potential for commercial applications, particularly in remote and economically disadvantaged areas where access to conventional energy sources is limited, offering a promising solution for sustainable energy generation.
2D dendritic thermal growth pulsations: diffusion field associated with the transport of heat for application in organic-based systems
Authors: Boyer Séverine A. E. , Burr Alain
Published: November 2024

The crystallization of organic-based materials occurs under conditions far from equilibrium, leading to patterns that grow as propagating waves into the surrounding unstable fluid medium. This problem was reformulated considering the concept of thermal forces of preexisting 2D patterns. A new finite difference numerical scheme was tested. Dendritic islands were distributed in the liquid-viscous fluid. It induced a heterogeneous thermal distribution nearby the dendritic islands. The evolution of the isoline of the temperature versus time reveals fractal patterns within the inter-dendritic liquid. The physical origin of the fluctuations is guided by the proximity of the dendrites, i.e. lack of space. Moreover, the gradient of temperature is depicted by isocline pictures. Fractal patterns may be considered advantageous and be taken as a key point to the next step, i.e. the crystal growth in an environment subjected to rapid variations of temperature.
Singular-plural verb stem alternation: uncovering global and local drivers of typological variation
Authors: Inman David , Vuillermet Marine
Published: November 2024

In this paper, we present a comparative concept for singular-plural verb stem alternation (Sg-Pl alternation) and a systematic global survey of its presence as well as its syntactic and semantic attributes, with a denser sample in the Americas. We show that Sg-Pl alternation is fairly common, occurring in about one in three languages, although its geographic distribution is highly uneven. Fine-grained data collected on the verbs targeted by the phenomenon reveal distinct global and local drivers. General semantic and syntactic properties are fairly consistent at the global level and reveal the relevance of the spatial configuration of the Figure (Motion Event), while at the local level highly specific semantics are shared across neighboring languages. This work will be of interest to both fieldworkers and typologists interested in distinguishing between the various causal factors for the development of typological properties.
Utilizing reactive oxygen species-scavenging nanoparticles for targeting oxidative stress in the treatment of ischemic stroke: A review
Authors: Shao Lingmin , Wang Can , Xu Gang , Tu Zewei , Yu Xinyuan , Weng Chao , Liu Jia , Jian Zhihong
Published: November 2024

Ischemic stroke, which accounts for the majority of stroke cases, triggers a complex series of pathophysiological events, prominently characterized by acute oxidative stress due to excessive production of reactive oxygen species (ROS). Oxidative stress plays a crucial role in driving cell death and inflammation in ischemic stroke, making it a significant target for therapeutic intervention. Nanomedicine presents an innovative approach to directly mitigate oxidative damage. This review consolidates existing knowledge on the role of oxidative stress in ischemic stroke and assesses the potential of various ROS-scavenging nanoparticles (NPs) as therapeutic agents. We explore the properties and mechanisms of metal, metal-oxide, and carbon-based NPs, emphasizing their catalytic activity and biocompatibility in scavenging free radicals and facilitating the delivery of therapeutic agents across the blood–brain barrier. Additionally, we address the challenges such as cytotoxicity, immunogenicity, and biodistribution that need to be overcome to translate these nanotechnologies from bench to bedside. The future of NP-based therapies for ischemic stroke holds promise, with the potential to enhance outcomes through targeted modulation of oxidative stress.
Mortality trends from all causes and diabetes mellitus according to sex between 1998 and 2021
Authors: Negrato Carlos Antonio , Medeiros Gabriel Araújo , Duarte de Souza Giordano Bruno , Lopes Lucas Casagrande Passoni
Published: November 2024

Introduction

The variation of mortality rates according to sex, regarding mortality from all causes and from specific conditions related to diabtes mellitus (DM) is widely discussed.

Aim

The aim of this study was to analyze the mortality trends from all causes and DM according to sex in Bauru, São Paulo, Brazil, between 1998 and 2021.

Methodology

This was a retrospective, observational, epidemiological, population-based study. Data were collected from the Unified Health System, the Brazilian Institute of Geography and Statistics, and the Automatic Recovery System. A time series analysis was conducted using age-adjusted rates for segmented analysis with annual percentage change and average annual percentage change (AAPC) computed.

Results

All-cause mortality rose from 2.080 to 3.806 deaths, an 82.31% increase, with a stable trend (AAPC: −0.70%). DM-related deaths increased from 84 to 168, with a stable trend (AAPC: −0.90%). Sex-specific mortality figures show a higher average mortality rate in males for all causes (26.50% higher) and females for DM (25% higher). All-cause mortality had a stationary trend for both sexes. DM mortality showed a slight decline in females (AAPC: −1.30%) but remained stable in males.

Conclusions

Men maintained a higher mortality rate from all causes when compared to women. Women kept a higher DM-related mortality rate than men, although their DM-related mortality rate showed a decreasing trend throughout the period evaluated.
Boethius of Dacia and Terence Parsons: Verbs and Verb Tense Then and Now
Authors: Sirridge Mary
Published: November 2024

Latin and English are good examples of languages in which temporal information is expressed to a significant extent by the tense system of verbs. Medieval speculative grammar dealt extensively with the grammar of tensed sentences and temporal adverbs. And starting in the 1960s, there was an explosion of theorizing about linguistic temporal indicators, principally tense systems and temporal adverbs, in anglophone linguistics and philosophical logic focused on semantics for natural language. I argue that despite important differences with respect to methodology and underlying assumptions, there is significant agreement about the underlying structure of constructions involving tense and the ontological commitments that follow from a semantic analysis of these constructions. I use as examples Modi Significandi by Boethius of Denmark and Events in the Semantics of English by Terrence Parsons.
Conjugated heat transfer characteristics of ribbed-swirl cooling in turbine blade under rotation condition
Authors: Xiao Kun , Zhao Xiandi , He Juan , Ma Zhaokai , Feng Zhenping
Published: November 2024

Ribbed-swirl cooling performs excellently in enhancing heat transfer, but previous studies were almost conducted in simple circular tubes under static conditions. The influence of actual mainstream flow, heat conduction of blade as well as the rotation effect was ignored. To explore its application potential in a real environment, the thermal performance of swirling cooling after adding annular ribs to its target surface in a real turbine blade was analyzed, and the impacts of centrifugal force along with Coriolis force were also included. From the results, the ribs affected the distribution of nozzle mass flow rate. For nozzles near the blade root, the mass flow rates in ribbed-swirl cooling were smaller than those in smooth-swirl chamber, while near blade tip, those were higher. Besides, the influence of Coriolis force from SS (suction side) to PS (pressure side) on the development of cross-flow and swirl in smooth and ribbed chamber exerted a significant difference. For ribbed-swirl cooling, cross-flow passing through ribs induced flow separation, which was conducted to cross-flow suppression. The combined action of the above two aspects led to an obvious heat transfer advantage of ribbed-swirl cooling. In comparison to smooth-swirl chamber, its blade surface temperature was further reduced to more than 25 K.
Práticas de escrita de crianças no contexto familiar: interlocuções com a BNCC na alfabetização
Authors: Piccoli Luciana
Published: November 2024

O objetivo deste trabalho é visibilizar e analisar práticas de escrita vinculadas ao contexto familiar de crianças de uma turma de 2º ano do Ensino Fundamental de uma escola municipal em Porto Alegre/RS, com enfoque nos gêneros e suportes textuais em circulação. Como desdobramento desse objetivo maior, ao final do texto, busca-se relacionar tais práticas e gêneros aos campos de atuação apresentados na Base Nacional Comum Curricular (BNCC) e levantar possibilidades pedagógicas para o trabalho com gêneros textuais na escola tendo em vista as práticas de escrita referidas pelas crianças. A pesquisa desenvolvida caracteriza-se por ser qualitativa e a abordagem metodológica empreendida para a geração de dados se deu através de grupo focal com doze crianças. Como considerações finais, argumenta-se que os gêneros do campo da vida cotidiana permitem que as crianças, sobretudo as das classes populares, possam estabelecer relações de aproximação com as práticas escolares.
DISCURSOS QUE INTERROGAM: EFEITOS DE APROXIMAÇÃO ENTRE LINGUÍSTICA E POÉTICA
Authors: Neumann Daiane , Milano Luiza
Published: November 2024

Apresentação ao Dossiê
A Conversation with Sandi DuBowski
Authors: Herzog Amy
Published: November 2024

An interview between Sandi DuBowski and Amy Herzog takes up the film Sabbath Queen, about Rabbi Amichai Lau-Lavie. Lau-Lavie’s family legacy spans at least thirty-seven consecutive generations of rabbis. Through Rebbetzin Hadassah Gross, Lau-Lavie’s drag alter ego, allows Lau-Lavie to experiment with multiple facets of his identity, “to be very queer, very spiritual, to navigate and fuse both.” DuBowski and Herzog explore themes, production processes, and formal decisions used in the film to portray Lau-Lavie’s relationships with his family and his communities.
No Bad Parts
Authors: Fawaz Ramzi
Published: November 2024

This essay argues that Inside Out 2’s critical success lies in its canny translation of three contemporary mental health discourses including Tibetan Buddhist mindfulness, holistic medicine, and the internal family systems model of the psyche. By presenting human emotions as a series of autonomous but interconnected parts struggling against being repressed and compartmentalized, the film models for viewers what a healthy relationship to one’s affective life might look like in an increasingly mentally distressed world. In so doing, it materially enacts the discourses of mental health, namely the injunction to reject emotional denial and compassionately embrace all one’s part, as an everyday way of life capable of offering viewers equipment for living.
LA BATALLA DE CLAVIJO DEL MUSEO COLEGIAL DE DAROCA (ZARAGOZA): UNA PINTURA SOBRE ÓNICE DEL CÍRCULO DE ANTONIO TEMPESTA
Authors: Carretero Rebeca
Published: November 2024

Este artículo da a conocer una pintura sobre ónice con la representación del apóstol Santiago en la batalla de Clavijo conservada en el Museo Colegial de Daroca (Zaragoza). Asimismo, se analizan con detalle las características artísticas de la pieza y su iconografía y, tras la comparación con su obra gráfica y pétrea, se adjudica al círculo del pintor italiano Antonio Tempesta (h. 1555-1630). Por último, se propone al obispo Martín Terrer de Valenzuela (1549-1631) como su posible propietario.
ДВА УВЕЩАНИЯ ЕВФИМИЯ ЧУДОВСКОГО В ЗАЩИТУ ПЕРЕВОДА КНИГИ «ПРАВОСЛАВНОЕ ИСПОВЕДАНИЕ ВЕРЫ»
Authors: Т.В. ПАНИЧ
Published: November 2024

В статье рассматриваются два сочинения на тему перевода и правки книг, принадлежащие перу одного из видных представителей русской духовной культуры второй половины XVII в. - знаменитого книжника, писателя, переводчика и редактора, грекофила Евфимия Чудовского. Оба сочинения написаны в форме полемического увещания и читаются в рукописи ГИМ, Синодальное собрание, № 473, где они предваряют текст книги «Православное исповедание веры» Петра Могилы в переводе Евфимия Чудовского. Анализируются структура и содержание увещаний, их идейная направленность и проблематика. На основе сопоставления текстов сочинений выявлены особенности каждого из них, показаны сходство и различия между ними, сделан вывод о том, что второе Увещание представляет собой новый текст, написанный на ту же тему, что и первое Увещание, с использованием отдельных фрагментов его текста.

The manuscript from the Synodal Collection of the GIM, No. 473, which is a list of Peter Mogila’s “Orthodox Confession of Faith” translated by Euthymius Chudovsky, contains, among additional articles, two works written in the form of instruction or Exhortation. The works were written on behalf of Patriarch Adrian, but, judging by the stylistic features of the text and the problems of the works, their author was Euthymius Chudovsky, who wrote Exhortations in defense of his translation of the book “The Orthodox Confession of Faith” from Greek. Both Exhortations are of interest as sources that allow a deeper understanding of the nature of the writing and translation activities of Euthymius Chudovsky, the specifics of his work with the word. The writings are polemical in nature and are directed at critics of book revisions and new translations. The author of the Exhortations substantiates the reliability of his translation, while revealing the principles and features of his work on translation and editing texts, as well as his attitude to the Greek language and the authoritative translations of the past. As for sources, he draws on the translation of the New Testament associated with the name of Metropolitan Alexiy, Conversations on the Gospel translated by Maxim the Greek, and the translation of the writings of the Fathers of the Church carried out by Epiphanius Slavinetsky. Despite the fact that both Exhortations are devoted to the same topic, a comparative analysis of their texts shows that they have significant differences. The text of the second Exhortation is much shorter (in volume, it is less than half of the first Exhortation). The differences relate to the structure, the nature of the text design, and stylistics. The first text looks like a rough draught, and the second one has an almost complete form. Based on the results of a comparative study of the texts of both works, it can be concluded that the second Exhortation should not be considered as an abridged version of the first Exhortation, but as a new text written on the same topic as the first Exhortation, using individual textual borrowings from it.
«ОКРУЖНОЕ ПОСЛАНИЕ ВИКАРИЯ МОНСЕНЬОРА ВЕЙО»: ПАМФЛЕТ Л.И. САЙН-ВИТГЕНШТЕЙН В ЗАЩИТУ Ф. ДЮПАНЛУ
Authors: Д.В. ДОЛГУШИН
Published: November 2024

В статье впервые публикуется памфлет, написанный Леониллой Ивановной Сайн-Витгенштейн на французском языке в поддержку епископа Орлеанского Феликса Дюпанлу в его полемике с консервативным католическим журналистом Луи Вейо. Текст приводится по рукописной копии из архива Славянской библиотеки (г. Ванв, Франция), сопровождается переводом на русский язык, текстологическим и реальным комментарием. Кроме того, в статье восстанавливается исторический контекст этого документа - ожесточенная полемика между французскими либеральными католиками и их противниками-ультрамонтанами. Памфлет представляет собой не только любопытный памятник полемики, проходившей в 1850-х гг. во Франции, но и документ, важный для изучения религиозных исканий и жизненного пути Л.И. Сайн-Витгенштейн, а также русско-французских культурных связей.

The purpose of the article is to study and publish a fragment of the French-language memoirs of Leonilla Sayn-Wittgenstein (née Baryatinskaya, 1816 - 1918), omitted during their publication in 1908. For the most part, this fragment contains the pamphlet written by L. Sayn-Wittgenstein around 1852 in support of Bishop of Orleans Félix Dupanloup in his polemic with the conservative Catholic journalist Louis Veuillot. The article expresses a judgment of exactly what place the pamphlet should have occupied in the general text of the memoirs, argues its dating, and restores the biographical context of the pamphlet’s writing. The general historical context, which is the polemic between French liberal Catholics and their ultramontane opponents, is reconstructed. It is concluded that the text of the pamphlet reflected many points of the controversy between Dupanloup and Veuillot, and the image of the “veuillotin”, a follower of Veuillot, was subjected to satirical hyperbolization. A “veuillotin” in the image of L.I. Sayn-Wittgenstein is aggressive, stubborn, stupid, arrogant, suspicious, unkempt, devoid of secular manners, fanatically devoted to Veuillot, holds bishops and the canonical system of the church in contempt, has extremely ultramontane views, and accuses his opponents of Gallicanism. The appendix to the article contains the text of the pamphlet based on a handwritten copy from the archive of the Slavic Library (kept as part of the archives of the Jesuit Order in Vanves near Paris). It is accompanied by a translation into Russian, textual and real commentary. The pamphlet is not only an interesting monument to the controversy that took place in the 1850s in France, but a document important for the study of the religious quest and life journey of L.I. Sayn-Wittgenstein, as well as for Russian-French cultural relations.
П.Н. БУЦИНСКИЙ VS И.П. БАРСУКОВ. ПОЛИТИЧЕСКИЙ КОНТЕКСТ СПОРА ИСТОРИКОВ О Н.Н. МУРАВЬЕВЕ-АМУРСКОМ
Authors: Н.П. МАТХАНОВА
Published: November 2024

В статье рассматриваются противоположные оценки выдающегося государственного деятеля, генерал-губернатора Восточной Сибири Н.Н. Муравьева-Амурского, данные известными историками XIX в. П.Н. Буцинским и И.П. Барсуковым. Освещена суть претензий Буцинского к Барсукову, высказанных в рецензии на фундаментальный труд Барсукова о Муравьеве-Амурском. Основная из них заключается в утверждении, что биограф необъективно отнесся к своему герою, который, по мнению рецензента, ненавидел М.М. Сперанского. Причиной неприязни Буцинский считал как зависть, так и противоположные подходы к управлению. В статье опровергается обвинение и уточняются позиции Муравьева-Амурского. Высказано предположение, что политическая подоплека обвинений Буцинским как Барсукова, так и Муравьева-Амурского заключалась в идейно-политических взглядах Буцинского - члена черносотенной организации.

The article considers a book review written by a famous historian, professor P.N. Butsinsky analyzing I.P. Barsukov’s fundamental work “Count Nikolay Nikolaevich Muravov-Amurskiy based on his letters, official documents, contemporary accounts and published sources (materials for biography)”. Barsukov’s book was nominated for the Metropolitan Macarius Prize of the Academy of Sciences, for which reason Butsinskiy was commissioned to write a review. Having accused the book’s author of the lack of objectivity the reviewer based his accusations primarily on the statements of the opponents of East Siberian Governor General. He demonstrated bias against both Barsukov’s work and its title character - Muravyov-Amursky, making insulting remarks regarding the latter. It is important to note one of Butsinskiy’s remarks that went beyond the review - he accused Muravyov-Amursky of hatred of the outstanding reformer M.M. Speransky. The historian believed that this hatred was rooted in the contrasting approaches to the problems of governance. Muravyov criticized Speranskiy’s “Siberian Statute” stressing its practical inconvenience. In Muravyov’s view, crucial miscalculations made by Speransky included introduction of collegiate administration and disregard for the Far Eastern territories. The nature of review was influenced by the general political environment and views of Butsinskiy. In particular, it was the negative attitude of the rightist who soon became an active member of the Black Hundred organizations towards the General Governor of Eastern Siberia who was rumored to be “red”, and the rightists’ negative perception of the active Far Eastern policy symbolized by Count Muravyov-Amursky. However, both the historians and the statesman who was the subject of their debate remained in the historical memory. Many streets and squares, museums and libraries in the cities of Siberia and Far East were named after Muravyov-Amursky. Monuments to him were installed in Khabarovsk, Chita, Blagoveshchensk and Vladivostok. Works by P.N. Butsinskiy and I.P. Barsukov have been reissued and are widely used and cited by contemporary historians.
ОСОБЛИВОСТІ ПРОГНОЗУВАННЯ ЗМІН КОТИРУВАННЯ АКЦІЙ З ВИКОРИСТАННЯМ КОВЗНИХ СЕРЕДНІХ І ОСЦИЛЯТОРІВ НА ПРИКЛАДІ КОМПАНІЇ НАФТОДОБУВНОЇ ГАЛУЗІ
Authors: САВЧЕНКО Вадим , БОБРОВ Євгеній
Published: November 2024

Сьогодні на курс акцій компанії впливає широкий спектр чинників: від фундаментальних внутрішніх факторів до політичних рішень влади, галузевих, макроекономічних і світових тенденцій. Відповідно, перед інвестором постає проблема як вибору підходу до визначення галузі й цільового активу, так і інтерпретації результатів аналізу, а також точки входу на ринок.
У цьому контексті розкрито ряд актуальних проблем прогнозування змін курсу акцій компанії нафтодобувної галузі Exxon Mobile Corp. на фондовій біржі, пов’язаних із специфікою використання таких інструментів технічного аналізу, як ковзні середні й осцилятори. Проаналізовано вплив налаштувань середніх ковзних різного типу, а також їх комбінацій на коректність прогнозування напрямку зміни котирування акцій компанії. Виходячи з цього сформовано завдання, які вирішуються використанням індикаторів такого плану. Запропоновано підхід до відбору індикаторів технічного аналізу та їх налаштувань при розробці системи прогнозування. Розглянуто різні варіанти формування та інтерпретації згенерованих індикаторами і їх комбінаціями сигналів щодо подальшої зміни курсу активу, а також кілька критеріїв співставлення результативності підходів на етапі тестування. Розраховано і порівняно результати використання кількох варіантів системи прогнозування, визначено оптимальні згідно з критеріями відбору. Для обчислень узято тижневі котирування з 2000 по 2024 р., на основі яких встановлено оптимальну комбінацію індикаторів для використання в системі прогнозування. Виокремлено зони можливої оптимізації та інструментарій, який може бути використаний для даних цілей. За результатами дослідження сформульовано висновок щодо можливості використання запропонованого підходу до побудови системи прогнозування для виконання реальних біржових операцій з акціями компанії.
Desarrollo de una bebida verde con espirulina (Arthrospira sp.) mediante el diseño experimental de mezclas
Authors: Bolaños-Quirós Fiorella , Fallas-Rodríguez Pilar , Murillo-González Laura , Pérez Ana M. , Quirós Ana M.
Published: November 2024

Introducción. Existe una tendencia al consumo de espirulina (Arthrospira sp.) por su valor nutricional y como fuente de proteína sostenible. La espirulina cuenta con sabor y olor intenso que puede generar desagrado a los consumidores, por lo que es conveniente el uso del diseño experimental de mezclas para la optimización de la formulación. Objetivo. Desarrollar un prototipo de bebida verde con alto valor nutricional con espirulina como ingrediente, mediante la aplicación de un diseño experimental de mezclas. Materiales y métodos. La investigación se llevó a cabo en la Universidad de Costa Rica sede Liberia, Guanacaste, entre julio y diciembre del 2022. Se elaboraron once prototipos de bebida con espirulina y se aplicó el diseño de mezclas (llenado del espacio) con tres factores (espirulina, azúcar, frutas/vegetales) y el agrado general como variable de respuesta. El agrado fue evaluado en un panel con 95 consumidores y los promedios se ajustaron al modelo de polinomial de Scheffe. Se obtuvo la ecuación del modelo del software JMP16 y se verificó en un panel con veintisiete consumidores y cinco muestras. Se realizaron análisis fisicoquímicos para obtener el valor nutricional de un prototipo seleccionado de la bebida. Resultados. Se encontró un efecto de los factores sobre el agrado del producto (p<0,05). Los valores de R2=0,97 y R2-adj=0,96 demostraron que el modelo se ajusta a los datos experimentales. La validación confirmó que el modelo logra predecir el agrado general. Se caracterizó la formulación con un 2 % de espirulina y una porción de 300 mL, se declaró como bajo en sodio, fuente de proteína y magnesio, rica en hierro y vitamina C. Conclusiones. Se logró obtener un modelo matemático significativo y ajustado que logra predecir el agrado de una bebida con espirulina. El prototipo desarrollado contiene más espirulina y proteína que bebidas similares del mercado.
Cristina Rocha, Cool Christianity: Hillsong and the Fashioning of Cosmopolitan Identities
Authors: Riches Tanya
Published: November 2024

Cristina Rocha, Cool Christianity: Hillsong and the Fashioning of Cosmopolitan Identities. Oxford: Oxford University Press, 2023, pp. 248, $35.44, ISBN: 9780197673201 (pbk).
PURPOSE TRENDS REPORT. A selection of what has been published about Purpose in May 2024
Authors: García T. , Flórez-Jiménez M.P. , Lleo A.
Published: November 2024

In this report, we want to synthesize the most relevant about corporate purpose published in May 2024. For this aim, we did a content search (using selected keywords) in Scopus and Google Scholar for academic publications; and diffusion magazines and other trusted sites for articles and reports. We selected relevant publications about organizational purpose and personal purpose. From January’s 2024 report onwards, the "purpose alignment" category will be discontinued and incorporated into the "organizational purpose" category, as the differentiation is minimal. Also, we include successful cases that show how corporate purpose has been implemented. Bellow, we present statistics about the selected literature.
Reflexões sobre as orientações da Unesco para a oferta da educação em prisões
Authors: Boutin Aldimara Catarina Brito Delabona , Flach Simone de Fátima
Published: November 2024

RESUMO A partir de pesquisa bibliográfica e documental, tendo como suporte teórico-metodológico o materialismo histórico e dialético, este texto teve por objetivo desvelar os limites e as possibilidades das orientações da Organização das Nações Unidas para a Educação, a Ciência e a Cultura (UNESCO) para a educação prisional no Brasil. Para tanto, inicialmente, o perfil social da população prisional brasileira é apresentado, tendo em vista sua relação com o acesso à educação; em seguida, são analisados os documentos legais que amparam o direito à educação para as pessoas privadas de liberdade e as orientações da UNESCO para a oferta educacional em prisões. A análise dos dados e dos documentos indica, por um lado, sua ancoragem em uma perspectiva neoliberal por meio de parcerias público-privadas e formação técnica para o mundo produtivo; e, por outro, a defesa da educação como direito das pessoas privadas de liberdade e como essencial para o processo de ressocialização.
Traçados acessíveis: características das produções escritas de estudantes universitários com Transtorno do Espectro Autista (TEA)
Authors: Dias Vivian Ferreira , Moreira Laura Ceretta
Published: November 2024

RESUMO Há ainda uma escassez de estudos que abordem a escrita do estudante com Transtorno do Espectro Autista (TEA) na fase adulta. Embora se admita que o ingresso de pessoas com TEA no ensino superior é ainda um fenômeno recente, este tem se tornado cada vez mais comum e o referido nível de estudo requer práticas de escrita bastante complexas. Obviamente, o ato de escrever não nasce nesse momento, já que a linguagem escrita é construída ao longo do desenvolvimento do sujeito, mas pode ser potencializada, e/ou dificultada, a depender das barreiras vivenciadas ou mediações oferecidas. No presente trabalho, esse caminho foi revisitado por meio da análise das produções escritas de 14 estudantes com TEA, de cinco Universidades Federais do sul do Brasil, com o intuito de apontar algumas particularidades das produções textuais do grupo em estudo. Os resultados, analisados pelo viés da linguística textual e pelo aporte discursivo, apontam que a produção textual, de modo geral, precisa de indicações detalhadas e as práticas “disfuncionais” devem ser reinterpretadas como formas alternativas de construção de sentidos. Mas, sobretudo os achados, indicam que as possíveis particularidades comportamentais do TEA (grande capacidade mnemônica, seguimento de regras, foco nos detalhes) surgem também nos escritos e as dispersões encontradas são reflexos da tentativa de controle dos sentidos e da contenção da complexidade da linguagem.
Educação OnLIFE e Cidadania Digital: o desenvolvimento do pensamentocomputacional na cidade em tempos de algoritmização do mundo
Authors: Menezes Janaína , Schlemmer Eliane , Felice Massimo Di
Published: November 2024

RESUMO A cidadania digital é a cidadania do mundo algoritmizado, datificado, conectado, sensorizado, dos metaversos, multiversos, big data. É a expressão de um novo tipo de arquitetura do social, constituído na reticularidade pela contínua conectividade entre humanos e não humanos. Uma conexão AtoBit, simbiótica, que potencializa a emergência de uma nova ecologia feita de pessoas, dados, algoritmos, sensores, florestas, clima, vírus, cidades. Essa conexão nos desafia a uma nova política cognitiva no campo da Educação. O artigo apresenta o conceito de Cidadania Digital e problematiza formas de conhecer e produzir conhecimento relacionado ao desenvolvimento do pensamento computacional na Educação Básica. Tem por objetivo compreender como o pensamento computacional é potencializado e produzido na cidade. As experiências se desenvolvem a partir de práticas pedagógicas inventivas, simpoiéticas, intervencionistas e gamificadas. Como método de pesquisa, se apropria do método cartográfico de pesquisa-intervenção para produção e análise de dados. Os resultados baseiam-se em elementos presentes nas epistemologias reticulares e conectivas, na cognição inventiva e nos conceitos de ato conectivo transorgânico e habitar atópico. Tais resultados indicam o pensamento computacional sendo potencializado no coengendramento entre entidades humanas e não humanas, numa perspectiva de Educação OnLIFE cidadã, contribuindo para a sua compreensão interdisciplinar e transversal, bem como para a valorização da comunidade. Esses resultados apontam para a emergência de uma política cognitiva ecológica em educação, o que implica repensar o currículo e a formação docente.
A formação docente para o ensino superior: impasses e perspectivas para a contínua aprendizagem
Authors: Salvador Maria Aparecida Tenório , Sordi Mara Regina Lemes De
Published: November 2024

RESUMO Este artigo foi elaborado a partir dos resultados da pesquisa desenvolvida no pós-doutoramento, que trata sobre a formação do docente do ensino superior, destacadamente, das Instituições Federais de Ensino Superior (IFES). Para subsidiar a compreensão sobre os resultados obtidos com as entrevistas semiestruturadas realizadas com os participantes do processo investigativo, discute-se a formação (inicial e continuada) de docentes iniciantes/ingressantes e veteranos das IFES participantes da pesquisa, e suas concepções acerca da formação e da prática pedagógica docente. Os dados obtidos revelaram que a formação permanente dos professores do ensino superior precisa ser compreendida como parte indissociável do exercício profissional docente e assumida pelas Instituições, com o protagonismo dos professores, que se ocupam da formação dos mais diversos profissionais.
AVALIAÇÃO EDUCACIONAL EM LARGA ESCALA E AS COMPETÊNCIAS SOCIOEMOCIONAIS: UMA REVISÃO INTEGRATIVA
Authors: Alves Moreira Dutra Kézia , Freitas Gama Jean Carlos , Stieg Ronildo , Dos Santos Wagner
Published: November 2024

Este artigo objetiva mapear e analisar a produção acadêmica que discute a avaliação educacional realizada em larga escala na correlação com as competências socioemocionais, de artigos publicados em periódicos, no intento de compreender as caraterísticas bibliométricas, bem como os conteúdos do que tem sido estudado, identificando tendências e lacunas ainda não exploradas. Metodologicamente, trata-se de uma pesquisa de natureza quanti-qualitativa de mapeamento da produção acadêmica, do tipo revisão integrativa. Como fontes, utiliza 46 artigos publicados em 36 periódicos, obtidos de um levantamento feito nas bases de dados Web of Science, Scopus, Scielo e Iresie. Inicialmente, notamos uma pulverização nas publicações, com autores de 28 países e em todos os continentes que discutem sobre a temática, o que indica que essa parece ser uma agenda global. Nesse universo de países, localizamos apenas três da América Latina, o que diz muito quanto à concentração dessas pesquisas e o não lugar latino diante de um contexto acadêmico internacional. Além disso, as análises dos artigos evidenciam três eixos a partir dos conteúdos destes: 1) avaliação educacional realizada em larga escala, educação e competências socioemocionais (relação direta com o tema); 2) avaliação de programas implementados em alguns países e/ou estados e instrumentos de aprendizagem socioemocional na psicologia educacional; 3) área da saúde com ênfase na psicologia do comportamento humano e processos mentais (transversalidade ao tema). Ressaltamos que as avaliações educacionais realizadas em larga escala são geradoras importantes de discussões sobre os aspectos referentes às peculiaridades dos sistemas educacionais.
LOS ESTILOS DE APRENDIZAJE EN LOS ESTUDIANTES DE EDUCACIÓN GENERAL BÁSICA
Authors:   Unidad Educativa República De Canadá, Páez Rivas George Michael , López Nieves María Jacqueline ,   Escuela de Educación Básica 29 de Junio, Indacochea Serrano Andrés Gabriel ,   Unidad Educativa Fiscomisional Don Bosco del Guayas
Published: November 2024

Cada ser humano es una individualidad, especialmente a la hora de aprender, debido a la imposibilidad de atender tan amplia especificidad los científicos educativos han creado grupos de estilos, desde el punto de vista psicológico, por edades, y hasta por sexos.

Los estilos de aprendizaje son las preferencias y enfoques que los niños utilizan para procesar y retener información. Son una combinación de factores cognitivos, fisiológicos y afectivos que determinan cómo se sienten más cómodos los niños a la hora de procesar, organizar y retener la información durante el proceso de aprendizaje.
Manejo del paciente crítico
Authors:   Universidad Estatal Península de Santa Elena UPSE, Ortiz Pilacuán Carmen Cecilia
Published: November 2024

Un paciente crítico es aquel que tiene uno o más sistemas de su cuerpo afectados, lo que lo pone en riesgo vital o en riesgo de quedar con graves secuelas. El manejo de este tipo de pacientes se realiza en unidades de cuidados intensivos por personal especializado en medicina de cuidados críticos. Algunos ejemplos de enfermedades que pueden llevar a un paciente a un estado más grave son: Insuficiencia respiratoria aguda; fracasos orgánicos cardiacos, hepáticos o renales; traumatismos severos; estado de shock. Los cuidados que requiere un paciente en esta condición puede incluir: Evaluar y registrar el estado y la evolución del paciente; garantizar la higiene del paciente; llevar a cabo el tratamiento médico prescrito; colaborar con el médico intensivista en el diagnóstico y las terapias; movilizar al paciente de manera segura cuando sea indicado; verificar la nutrición del paciente; participar en el relevo de enfermería; mantener una asepsia impecable, entre otros.
For the 80th anniversary of B. L. Krasniy
Authors: Editorial Article
Published: November 2024

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Rheological сharacteristics of highly concentrated silica glass suspensions for 3D printing of refractories
Authors: Sharafeev Sh. M. , Kaz’mina O. V. , Gubanov A. V. , Mezhenin A. V. , Polushin G. V. , Kutugin V. A.
Published: November 2024

The present study investigates the impact of quartz, mullite, spinel, and corundum fillers on the rheological properties and extrudability of silica glass suspension-based compositions. The results indicate that materials containing mullite, spinel, and corundum exhibit dilatant flow, which impedes their use as inks in 3D printing. Conversely, suspensions containing quartz filler display a nonlinear viscoplastic flow. The addition of polyvinyl alcohol to compositions with quartz filler enhances their shape retention factor during extrusion by increasing their yield stress and viscosity. Ill. 5. Ref. 19. Tab. 1.