bluuebunny/crossref_metadata_2025 huggingface dataset:
Globalisation processes and tourism industry development in North-East Asia (Korea, China, Japan)
Authors: Kan Den Sik , Vasylchuk Volodymyr M. , Chuprii Leonid V. , Datskiv Igor B. , Kravets Kateryna P.
Published: November 2021

The paper covers relevant issues, such as the current state of the tourism services sector in China, Japan, and South Korea. The significance is confirmed by the growing role of the North-East Asian countries in the world trade in services and the growing contribution of tourism to the global gross domestic product. The purpose of this study is to identify the features, problems, and prospects for the development of the tourism services sector in China, Japan, and South Korea. The paper uses methods of systematisation and typification, which made it possible to determine the specifics of the development of cultural tourism in the Far Eastern region among the current range of opinions and areas of cultural tourism research. The study uses the principles of historicism and objectivity, which allowed analysing the development and current state of tourist exchange. A cultural approach was also used to reconstruct the cultural and humanitarian population of North-East Asia through the mutual enrichment of nations and people. The systematic approach made it possible to understand the importance of humanitarian exchange between people and identified the universality of tourism.
Men's Bones Matter Too, a Cross Sectional Study Examining Bone Health among Men with Intellectual Disability in Ireland.
Authors:   Trinity Centre for Ageing and Intellectual Disability, School of Nursing and Midwifery, Trinity College Dublin, Ireland, Burke Éilish A , Carroll Rachael ,   Trinity Centre for Ageing and Intellectual Disability, School of Nursing and Midwifery, Trinity College Dublin, Ireland, Ding Angela W. ,   School of Nursing, University of Pennsylvania, 418 Curie Blvd, Philadelphia PA 19104, US, Yaman Melisa ,   School of Nursing, University of Pennsylvania, 418 Curie Blvd, Philadelphia PA 19104, US, Walsh J. Bernard ,   Medical Gerontology, School of Medicine, Trinity College Dublin, McCallion Philip ,   College of Public Health, Temple University, Bell Building, 1101 W. Montgomery Ave, Philadelphia, PA 19122, McCarron Mary ,   Trinity Centre for Ageing and Intellectual Disability, School of Nursing and Midwifery, Trinity College Dublin
Published: November 2021

Globally between 30-40% of all osteoporotic fractures occur among men, with a quarter of all hip fractures, the most serious complication of osteoporosis, occurring in men. Among men of 50 years of age or older, osteoporotic fracture risk reaches an alarming 20%. What is of great concern is that associated mortality is greater among men when compared with women. For hip fractures specifically, mortality for men is two to three times that in women which may be attributed to the fact that osteoporosis is often considered a “women’s disease”. Of great concern is that there is a paucity of bone health investigation among men with intellectual disability. In the Intellectual Disability Supplement to The Irish Longitudinal Study on Ageing, objective bone status of 244 men was measured using a quantitative ultrasound. Participant’s also self-reported doctor’s diagnosis of health conditions including osteoporosis, medication and fracture history with the assistance of key workers/family. Ethical approval for the study was obtained from the Faculty of Health Sciences Trinity College and all participating service providers. Overall, 70.9% of men presented with poor bone health, with 57.8% taking at least one medication that contributed to osteoporosis/osteopenia. Men had a high prevalence of fracture (21.7%) despite this less than 18% had attended bone health screening. In light of these findings, it is time for the spotlight to focus on men’s bone health and for healthcare professionals to realise how ‘at risk’ of osteoporosis are men with intellectual disability. Projections place men on a trajectory of continuous increased risk of fracture in comparison to women.
Molasses as a new nutrition medium for Scenedsmus quadricauda growth and production of some bio compounds
Authors: AL –Shahery Yousef J.I. , AL-Asady Israa N.
Published: November 2021

Algae comprise a large group of Thallophyta, which may be used as direct nutrition of human beings. Molasses is the by-product of the sugar manufacturing facility. In this study, a locally isolated Scendsmus quadricauda from the environment of Mosul in the Shalalat region was obtained. Biomass of Scenedsmus was measurement by carried out and filtration then drying in an oven for 24 h and weighed, Estimation of chlorophyll and protein and carbohydrate content of Scenedsmus. The research has proved that the best growing period for Scendsmue quadricauda is 15 days when using sugar factory waste as a carbon source, the growth reached (1.42 nm) as optical density, biomass (1525 mg /L), chlorophyll (green), pigment (18 mg /l) protein content (396 mg /l ) and carbohydrates ( 501 mg / l ). The research showed that the use of sugar factory waste as a nutritional medium for algal growth in the dark (11.5%) achieved good growth of Scendesmues quadricauda ( 0.632 nm), biomass (820 mg / L), green pigment (Chlorophyll) (18 mg /L) protein content (235 mg / L ) and carbohydrates (401 mg/L). while using phosphor (0.018%) of K2HPO4 in dark medium achieved highest growth rate (0.91 nm) , biomass (1110 mg / L) chlorophyll ( 22 mg/L) protein (301mg/L) and carbohydrate (461 mg/L) . It is noted too , that using IAA (0.5 g/L) in dark medium support best growth (0.888 nm) , biomass (1010 mg/L) chlorophyll (25 mg/L) , protein (230mg/L) and carbohydrate (440 mg//L) . The study showed that thiamine (1 g/L) in dark medium achieved highest growth (0.750 nm) biomass (218 mg/L), chlorophyll (29mg/L), protein (220 mg/L), carbohydrate (340mg/L). Therefore, using Molasses can enhance the growth, biomass, chlorophyll, protein, and carbohydrate content in the S. quadricauda.
Abstracts of the IV Scientific symposium with international participation “Musculoskeletal diseases and age” dedicated to the memory of V.V. Povoroznyuk (October 21–22, 2021, Kyiv, on-line)
Authors: Authors No
Published: November 2021

No abstract
РАЗРАБОТКА MIMO-РАДАРА НА БАЗЕ ФКМ-СИГНАЛОВ
Authors: Переверзев А.Л. , Лялин К.С. , Мелёшин Ю.М. , Карпов В.Н. , Колесников Р.Н.
Published: November 2021

Представлены результаты разработки MIMO-радара на базе ФКМ-сигналов Ku-диапазона частот, предназначенного для обнаружения БПЛА и других летающих объектов и обладающего высокой разрешающей способностью по скорости и по пространственным координатам. Приведен расчет требуемых характеристик радара и описан процесс разработки его конструкции.
Regeneration of Dead Bougainvillea Tree with Organic Manure
Authors: Bajaj Dr. Ram
Published: November 2021

Abstract: Bougainvillea is hard, woody climber tree, grow in high salt tolerant soil. The present study was carried out in regenerating Bougainvillea plant with organic manure. The research work was conducted at kitchen garden campus in January 2020. The collected soil samples of five trees species namely Pimple, Neem, Khejari and Rohira are mixed with 10kg fresh cow dung, 5kg cow urine, 2kg molasses & 2kg flour Kitchen wastes 10kg, Charcoal 10kg, Molasses 2kg, Rice 1kg, Humus 10kg, Wheat 10kg, Crashed sugar cane 10kg, Chicken manures 2kg, Wooden saw dust, Wooden chips & Rice lusts and mixed with water for preparing organic product. The organic product keeps for 3 days in open conditions. The prepared organic product was poured into the shoot and root. Later, the regrowth of the shoot and the root were reported in 4-5 months. The organic product enhanced the metabolism for regenerating permanent tissue and Meristematic tissue of Shoot horizon and root horizon. Later, The lateral branches and flower were emerged from the dead plant. The formulated organic product is competent to regrow dead plant. Keywords: Bougainvillea, Dead plant, organic manure, regeneration, soil, climate
Directivas anticipadas en Uruguay: Incorporación a la práctica médica en el presente
Authors: De los Santos Héctor
Published: November 2021

Introducción: La ley número 18473 de voluntades anticipadas fue promulgada en Uruguay en el año 2009, reglamentándose cuatro años después. Esto evidencia una propensión hacia la autonomía y la planificación del futuro de los enfermos. Objetivo: Determinar el conocimiento por parte de los profesionales de la salud en cuanto a la ley, su empleo en la clínica y acceso al formulario de voluntades anticipadas. Método: Investigación descriptiva, mediante una encuesta anónima a médicos uruguayos generales y especialistas en actividad, enviada por redes sociales. Resultados: Se obtuvieron 363 respuestas, con un 97 % de profesionales que atendían enfermos, un 79,5 % no habían extendido el documento y más del 50 % no tenía conocimiento de la ley. Conclusión: El conocimiento sobre las voluntades anticipadas en el cuerpo médico uruguayo es escaso y es aún más su aplicación a los pacientes.
Assessment of the Potential Natural Status of Riparian Zones in the Czech Republic
Authors: Jakubínský Jiří , Prokopová M. , Cudlín O. , Purkyt J. , Štěrbová L. , Pechanec Vilém , Cudlín Pavel
Published: November 2021

Riparian zones represent an important ecosystem providing a range of
functions and services important to humans—e.g., biodiversity support,
a reduction in erosion risk, or the transport of pollutants from the
surrounding landscape to watercourses. At the same time, it is,
unfortunately, an environment that has been often subjected to
significant pressure during the agricultural cultivation of the
landscape or the development of industrial and residential activities of
human society. Thus, a large number of riparian ecosystems have
disappeared or degraded. The assessment of the overall ecological status
of riparian habitats constitutes an important source of information for
the needs of watercourse management and landscape planning in the
riparian landscape, the aim of which should be to maintain good status
or to improve the current unsatisfactory state of these habitats.
However, in order to reliably evaluate the current ecological status of
the landscape, it is necessary to have information on the reference
status, i.e., a potentially natural status that would prevail without
human influence. For this purpose, a methodology that can determine the
potential natural status of riparian zones in Central European
conditions was developed. In this study, it was found that approximately
a quarter (26 %) of all river basins in the Czech Republic reach very
low environmental values of the potential natural status of riparian
zones and, conversely, approximately 29 % of river basins are expected
to develop significantly above average riparian zone quality if we
neglect human impact.
Sudden Sensorineural Hearing Loss in a Hyperbaric Oxygen Chamber Employee Following Parotidectomy
Authors: Ideker Henry , Walker Ronald , Sappington Joshua
Published: November 2021

Sudden sensorineural hearing loss (SSNHL) is uncommon and oftentimes
idiopathic. We describe the unique presentation of SSNHL in an HBO
chamber employee following a parotidectomy, whose chief complaint was
otalgia and aural fullness during dives. She ultimately recovered
completely due to timely diagnosis and a high-dose steroid taper.
Diversity Beyond Demographics: Environmental Worldviews of Forestry and Natural Resource Undergraduate Students
Authors: Cruz Sativa , Batavia Chelsea , Spalding Ana , Arismendi Ivan , Nelson Michael
Published: November 2021

In U.S. academic institutions, efforts often concentrate on enhancing
the recruitment of students from underrepresented groups, focusing on
gender and/or race. Yet, non-demographic forms of diversity have
received little attention, such as environmental worldviews, i.e.,
differences in the metaphysical, epistemological, and ethical beliefs
that define how humans view, value, and interact with the natural world.
Here, we develop an exploratory measure of environmental worldview
diversity among undergraduate students enrolled in natural resource
related programs. We tested our procedure at Oregon State University, a
large public land-grant university in the US. Many students reported
metaphysical, epistemological, and/or ethical beliefs that deviate from
what has been philosophically characterized as the dominant western
worldview of natural resources (anthropocentric, dualistic,
hierarchical, utilitarian, mechanistic). Our results suggest that,
although forestry students’ environmental worldviews are in some ways
more closely aligned with the dominant western worldview than other
students in natural resources, generally their worldviews reflect
long-term generational shifts away from a strict resource-commodity
value orientation, as documented in past research. Our findings
highlight the importance of considering environmental worldviews as a
dimension of diversity within the new generation natural resource
students. Future efforts toward understanding these levels of difference
can be important assets in designing programs which appeal to wide
variety of students; ultimately helping efforts to recruit and retain a
diverse of aspiring natural resource professionals.
On geometric space and its applications in topological Hv-groups
Authors: Ardakani Hamid , Pourhaghani Asieh
Published: November 2021

We generalize the concept of topological hypergroup to topological Hv-group
and define some topologies on Hv-groups by using the concept of geometric
space, which was defined by Freni. By applying these topologies, we have
always a topological Hv-group without need any more conditions. Moreover, we
state some conditions on a topological Hv-group that make it complete. Our
aim is to generalize the concept of topological hypergroup to
topological Hv-group via considering the characteristics of the induced
geometric space.
Endoscopic Sinus Surgery
Authors: Safi Chetan , Gudis David A. , Oswald Aaron
Published: November 2021

Endoscopic sinus surgery has revolutionized the field of otolaryngology and is now the surgical standard of care in treating most paranasal sinus disorders. A graduating otolaryngology resident must be proficient in performing endoscopic sinus surgery (ESS) to care for common sinonasal pathology. Thus, our goal with this chapter is to provide a systematic guide of ESS for surgeons at all stages of training. We discuss the indications for ESS, the thorough review of preoperative computed tomography, the intraoperative technique for ESS, as well as complications. We believe that careful review of this chapter will provide physicians with a comprehensive base to understand the concept of endoscopic sinus surgery and will allow them to develop their technique and skills as they continue to train.

This review contains 5 figures, 5 tables, 34 references
Keywords: Endoscopic Sinus Surgery, Surgical Education, Surgical Technique, Surgical Complications, Open Sinus Surgery Approaches
Summary and comments: Anabolic-Androgenic Steroid Use in Sports, Health, and Society
Authors:   Rio Ave F C. Vila Nova de Gaia, Ribeiro Basil , Dores Hélder ,   Hospital da Luz; S L Benfica. Lisboa, Rêgo Carla ,   Hospital CUF, Faculdade de Medicina do Porto, Milheiro Jaime ,   CMEP, Porto, Escaleira Rui ,   Hospital Viana do Castelo, Federação Portuguesa de Natação, Correia Osvaldo ,   Clínica Epidermis, Porto
Published: November 2021

O Colégio Americano de Medicina Desportiva (ACSM) publicou em agosto (2021) uma atualização da declaração de consenso sobre o consumo de estrogénios estrogénicos anabolizantes (EAA). A edição anterior datava de 1987 e devido ao acumular de enorme quantidade de informação desde essa data tornou-se necessário fazer esta atualização. O documento refere que o paradigma de utilização dos EAA mudou, pois, se no passado os maiores consumidores encontravam-se no desporto de competição, atualmente o maior consumo ocorre nos atletas de recreação com o objetivo de, ilicitamente, melhorarem o rendimento e o aspeto físico. O ACSM declara que o uso de EAA pelos atletas é proibido pelas várias organizações desportivas, pelo que discorda da sua utilização. Os Prof. Drs. Carla Rêgo, Osvaldo Correia, Hélder Dores e os Drs. Rui Escaleira e Jaime Milheiro comentam este tema.
Laparo-endoscopic Approach for Large Ovarian Cyst in the Morbidly Obese: Case Report
Authors: Goh Wei-An , Tan Eunice MX , Nadarajah (MRCOG) Ravichandran
Published: November 2021

We report a successful case of laparo-endoscopic single site total hysterectomy and bilateral salpingo-oophorectomy (LESS THBSO) using conventional laparoscopic instruments for a large ovarian cyst in a morbidly obese woman. A 58-year-old female with a BMI of 46kg/m2 complaint of abdominal distension. A pelvic ultrasound revealed a left ovarian cyst measuring 21.3 x 15.2 x 20.8 cm. The IOTA score is 3.5% and the RMI score was 51, suggesting a benign pathology. LESS THBSO was performed and the final histology was a benign ovarian mucinous cystadenoma. The patient recovered well with no postoperative complications. This case demonstrates that LESS is feasible for large ovarian cysts even in morbidly obese patients when appropriate cases are selected and when the patient is managed in a multi-disciplinary team.
RESPONS PADI GOGO VARIETAS DODOKAN TERHADAP PEMBERIAN PUPUK KOMPOS DAN NITROGEN PADA TANAH ULTISOL DI KECAMATAN NATAR KABUPATEN LAMPUNG SELATAN
Authors: Putri Randona Yeka , Yafizham Yafizham , Hermanus Hermanus , Sunyoto Sunyoto
Published: November 2021

Penelitian ini bertujuan untuk mengetahui pengaruh dosis pupuk kompos dan nitrogen terhadap pertumbuhan dan produksi padi gogo. Perlakuan ini menggunakan Rancangan Kelompok Teracak Sempurna (RKTS) yang disusun secara faktorial (4x3) dengan tiga ulangan. Faktor pertama yaitu pupuk kompos (0 , 5, 10 dan15 t ha-1). Faktor kedua adalah pupuk nitrogen (0, 45 dan 90 kg ha-1). Homogenitas data diuji dengan uji Barlet dan aditivitas data diuji dengan uji Tukey dan dilanjutkan dengan uji BNT pada taraf nyata 5 %. Hasil penelitian menunjukkan bahwa pemberian pupuk kompos berpengaruh pada jumlah anakan ,panjang malai dan hasil panen padi. Sedangkan pemberian pupuk nitrogen berpengaruh pada tinggi tanaman (35, 42, 49 HST), jumlah anakan produktif dan hasil panen padi. Interaksi antara pemberian pupuk kompos dan nitrogen terjadi pada tinggi tanaman (49 HST) dan pada jumlah anakan produktif. Dari penelitian ini pemberian kompos pada dosis 5, 15 t ha-1 dan nitrogen 90 kg ha-1 memberikan pengaruh yang lebih baik terhadap pertumbuhan padi gogo. Hasil analisis tanaman padi menunjukkan bahwa serapan N yang terserap sebanyak 1,47%.
Problem-Based Workshop For Improving Product Diversification Of The Kolang-Kaling Process
Authors: Desnita Desnita , Iryani Iryani , Darvina Yenni
Published: November 2021

Tanah Datar Regency is known as one of the abundant fruit-producing areas of Kolang-Kaling. According to an interview by the PKM team with one of the heads of the women farmer groups, it was revealed that every week as many as 3 tons of Kolang-kaling fruit can be harvested. However, they only process 10% traditionally (boiled, peeled, and sold). The community does not have sufficient competence to apply technology in processing these plantation products into ready-to-eat food. As a result of the agreement with the two Cempaka Mekar and Teratai Women's Farmer Groups, also with the approval of the village head , a community partnership activity was agreed upon for these two farmer groups. With the aim of increasing the competence of women who are the target of activities in the application of technology for processing kolang-kaling fruit . Increasing competence is expected to have an impact on the welfare of the target community. In order to achieve the objectives, a problem-based workshop model was chosen, where the workshop activities were conducted based on partner problems, with an andragogical approach
Hubungan Status Gizi Terhadap Tingkat Aktivitas Fisik PMI Selama Masa Karantina Covid-19
Authors: Hita I Putu Agus Dharma , Ariestika Elsa , Billy Yacs Betrix Teofa Perkasa Wibafiet , Pranata Doni
Published: November 2021

Abstrak

Seluruh aspek kehidupan mengalami penyesuaian sejak pandemi covid-19. Hal ini menjadi sangat penting untuk menjaga kebugaran tubuh dengan melakukan aktivitas fisik melalui olahraga, agar imunitas tubuh terjaga serta terhindar dari virus dan penyakit lainnya. Penelitian ini bertujuan untuk mengetahui hubungan status gizi terhadap tingkat aktivitas fisik Pekerja Migran Indonesia (PMI) selama masa karantina covid-19 di Kabupaten Jembrana, Provinsi Bali yang dilakukan selama 14 hari. Penelitian ini merupakan jenis penelitian korelasional. Instrumen yang digunakan yaitu lembar recall physical activity 24 jam selama 14 hari untuk mengumpukan data status gizi dan tingkat aktivitas fisik. Setelah data terkumpul akan dilakukan uji normalitas menggunakan teknik kolmogorov smirnov dan uji homogenitas menggunakan teknik levene statistic dengan taraf signifikan 5% (p > 0.05). Selanjutnya, uji hipotesis menggunakan teknik korelasi dengan taraf signifikan 5% (p < 0.05). Hasil penelitian menunjukan bahwa data berdistribusi normal dengan nilai sig 0.167 (status gizi) dan sig 0.073 (tingkat aktivitas fisik) p > 0.05 dan data bersifat homogen dengan nilai sig 0.133 (p > 0.05). Hasil uji hipotesis dengan teknik korelasi mendapatkan hasil nilai sig sebesar 0.005 (p < 0.05), sehingga dapat disimpulkan bahwa terdapat hubungan yang signifikan status gizi terhadap tingkat aktivitas fisik PMI selama masa karantina covid-19 di Kabupaten Jembrana.

Kata Kunci: status gizi, tingkat aktivitas fisik, covid-19
Pengaruh Bentuk Latihan Squat Jump Terhadap Kekuatan Shooting Sepakbola Atlet Pro:Direct Academy
Authors: Arwandi John , Ridwan M , Irawan Roma , Soniawan Vega
Published: November 2021

Masalah dalam penelitian ini adalah kekuatan shooting atlet masih jauh dari yang diharapkan, karena terbukti dari banyaknya shooting yang dilakukan oleh atlet baik dalam pertandingan maupun latihan sangat sedikit yang bisa menghasilkan gol. Penelitian ini bertujuan untuk mengetahui pengaruh bentuk latihan squat jump terhadap kemampuan shooting di dalam permainan sepakbola atlet Pro:Direct Academy. Metode yang digunakan dalam penelitian ini adalah penelitian eksperimen dengan pengambilan data kuantitatif. Populasi dalam penelitian ini adalah seluruh atlet Pro:Direct Academy sebanyak 85 orang. Teknik sampling yang digunakan pada penelitian ini yaitu purposive sampling, dengan kriteria atlet yang sudah berlatih selama setahun. Maka sampel dalam penelitian ini adalah atlet U17-U18 sebanyak 20 or. Instrumen penelitian yang digunakan adalah alat tes kecepetan dan kekuatan shooting yang diberikan sebelum dan sesudah perlakuan bentuk latihan squat jump kepada atlet. Analisa data menggunakan uji-t. Hasil penelitian yang diperoleh menunjukan bahwa t-hitung untuk hasil tes kekuatan sebesar 3,548, di mana nilai tersebut lebih besar dari nilai tabel dengan derajat bebas 19 dan taraf signifikansi sebesar 1% yaitu 2,539. Sehingga dapat disimpulkan bahwa perlakuan berupa latihan squat jump memberikan pengaruh yang signifikan terhadap kekuatan shooting di dalam permainan sepakbola.
Influence of inorganic nutrients on growth, flowering and quality of Dendrobium cv. Singapore white
Authors: Nair Sujatha A , Sankar V , Muralidhara B M , Awcharae C M , Singh D R
Published: November 2021

Dendrobium orchid cv. Singapore White is cultivated commercially for cut flower purpose. The performance of this orchid in response to the different nutrient concentrations was evaluated under the agro-climatic conditions of Kodagu during 2017-2020. Twelve nutrient doses were applied as foliar sprays at weekly intervals to study their effect on vegetative growth, flower production and quality parameters of the cut flowers. Plant height, number of leaves plant-1, leaf area, number of pseudobulbs plant-1, number of spikes plant-1 year-1, number of flowers spike-1 and spike length varied significantly with the nutrient doses. Foliar spray of 30:20:20 NPK 0.1% at weekly intervals recorded the maximum plant height of 53.21cm, number of spikes plant-1year-1 (10.01) with spike length of 44.43 cm and 16.20 flower spike-1.
Cardiovascular complications during the treatment of castration-resistant prostate cancer with the use of modern antiandrogens: abiraterone acetate and enzalutamide
Authors: Grabysa Radosław , Chmielewska Agnieszka
Published: November 2021

Modern antiandrogens: abiraterone acetate (inhibitor of CYP17 cytochrome) and enzalutamide (irreversible inhibitor of androgen receptor) are the drugs that are increasingly often administered in treatment of castration-resistant prostate cancer. Despite their clinical efficacy, especially in terms of prolonged survival and improved quality of life of patients, they pose of problem for a practicing oncologist such as possible cardiovascular complications (particularly arterial hypertension), which may lead to the cessation of this form of therapy. This article provides a brief overview of the mechanisms responsible for the above complications, including practical recommendations in the event such complications arise. A simple scheme of action for control of cardiovascular risk factors has been presented, which can improve the prognosis in this population of patients.
Upaya Menurunkan Tekanan Darah pada Lansia Melalui Terapi Shalat Dhuha
Authors: ISTIANA DIAN , PURQOTI DEWI NUR SUKMA , ROMADHONIKA FITRI , Pusparini Mita
Published: November 2021

Hipertensi sudah menjadi masalah kesehatan yang cukup tinggi di dunia tidak hanya ditemukan pada Negara maju tapi dijumpai juga pada negara- negara berkembang. Ketika tensi berada pada angka diatas 140 mmHg untuk tekanan darah sistolik dan di atas angka 90 mmHg untuk tekanan darah diastolik maka kondisi inilah disebut hipetensi. Hipertensi banyak dijumpai pada lansia, beberapa faktor yang melatarbelakangi lansia mengidap hipertensi antara lain faktor kepekaan terhadap kadar garam, reaktivitas pembuluh darah terhadap vasokonstriktor, pola makan, kebiasaan merokok, stress emosi, kegemukan dan lain-lain. Adapun tata laksana pengendalian tekanan darah tinggi ada dua jenis yaitu pengebotan medis dengan obat-obatan dan pengendalian tanpa obat atau teknik relaksasi yang bertujuan untuk merelaks kan otot-otot dan organ sehingga mampu menurunkan tekanan darah. Tujuan dari kegiatan pengabdian ini adalah pengenalan cara pengendalian tekanan darah berupa pelaksanaan terapi shalat dhuha. Panti Sosial Tresna Werdha Provinsi Nusa Tenggara Barat merupakan mitra pada pelaksanaan pengabdian ini. Metode yang dikukan dalam kegiatan pengabdian ini dengan pelaksanaan terapi shalat dhuha selama 7 hari berturut-turut sebanyak 4 rokaat setiap harinya. Hasil dari kegiatan pengabdian ini didapatkan penurunan tekanan darah setelah dilakukannya terapi shalat dhuha. Setelah  pelaksanaan kegiatan pengabdian ini diharapkan terapi shalat dhuha tetap dilaksanakan secara rutin untuk mengendalikan tekanan darah agar tetap stabil.---Hypertension has become a fairly high health problem in the world not only found in developed countries but also in developing countries. When tension is above 140 mmHg for systolic blood pressure and above 90 mmHg for diastolic blood pressure then this condition is called hipetension. Hypertension is found in the elderly, several factors behind the elderly have hypertension, among others, factors of sensitivity to salt levels, vascular reactivity to vasoconstrictor, diet, smoking habits, emotional stress, obesity and others. As for the procedure of controlling high blood pressure there are two types of medical sabotage with drugs and control without drugs or relaxation techniques aimed at relaxing the muscles and organs so as to lower blood pressure. The purpose of this devotional activity is the introduction of a way of controlling blood pressure in the form of the implementation of dhuha prayer therapy. Tresna Werdha Social Home in West Nusa Tenggara Province is a partner in the implementation of this service. The method carried out in this devotional activity with the implementation of dhuha prayer therapy for 7 consecutive days as many as 4 rokaat every day. The result of this devotional activity was obtained a decrease in blood pressure after the dhuha prayer therapy. After the implementation of this devotional activity, it is expected that dhuha prayer therapy will still be carried out regularly to control blood pressure in order to remain stable.
Brief analysis: development of nuclear submarines and elaboration of industry standards for power plant systems
Authors:   ", Kirikova Valeria ,   Malachite",   Design Bureau, St. Petersburg, Russia
Published: November 2021

Object and purpose of research. A wide application of nuclear technologies and new types of weapons, electronic sensors, automation systems and tools have increased combat capabilities of the Navy and its major component represented by submarine forces. Materials and methods. Nuclear submarines are core weapons of the Naval Forces, which can efficiently perform strategic and tactical roles, including multiple tasks. Main results. This paper briefly analyzes the steam-generation and steam-turbine plants development of submarines and elaboration of industry standards used for design of the systems supporting of nuclear submarines. Conclusions. This paper assesses the relevancy of standards used in development of steam-generation and steam-turbine plants for advanced nuclear submarines and identifies the scope for their further improvement to take into account modern nuclear submarine requirements in the design.
Promising fields of system research in man-made marine noise
Authors:   Krylov State Research Centre, St. Petersburg, Russia, Tarovik Vladimir , Valdman Nikolay ,   Krylov State Research Centre, St. Petersburg, Russia, Labuzov Andrey ,   Krylov State Research Centre, St. Petersburg, Russia, Malyarenko Nina ,   Krylov State Research Centre, St. Petersburg, Russia
Published: November 2021

Object and purpose of research. This paper discusses current international regulations governing man-made noise in marine environment. Systematization of normative documents issued by a number of international classification societies, as well as of the documents released by the international organization dealing with life safety of marine ecosystems highlighted the necessity for the Russian Federation to develop a similar regulatory basis of its own. This paper is a review of international standards and rules for man-made underwater noise, as well as of current international programs dealing with research, regulation and control of man-made underwater noise. Materials and methods. This paper is based on KSRC-developed methodical materials, international standards for underwater noise, as well as available publications in this sphere, both Russian and foreign. The study followed the methods of system analysis. Main results. Systematization of the data on current regulations for underwater noise of various ships, like cargo carriers, research vessels, seismic survey ships and fishing craft. The study concludes that Russia needs a similar regulatory basis that would cover offshore drilling rigs (both wildcat and production), underwater mining systems and subsea pipelines, large ships with high ice class, icebreakers and icebreaker-led caravans, as well as port infrastructure along Northern Sea Route lanes. Conclusion. To develop its own regulatory basis intended to set out the rules for man-made underwater noise, Russia needs a wide-scale systematic research campaign that would tackle the sources of man-made underwater noise at each lifecycle stage of any marine technology. This systematic research would pave way to a scientifically justified regulations for underwater noise of marine industrial facilities, shipping and port infrastructure.
Pääkirjoitus: Lain tuulia avoimen tieteen purjeissa
Authors: Juuso Ala-Kyyny
Published: November 2021

Vuonna 2015 haastattelin yliopistokirjastojen asiantuntijoita avoimesta julkaisemisesta opinnäytetyötäni varten. He olivat yksimielisiä siitä, että muutos kohti avointa tiedettä tapahtuu sitovien linjausten ja akateemista maailmaa ohjailevien tahojen, kuten tutkimusrahoittajien ja ministeriön, tuella.
Baldwin IV of Jerusalem as the image of the ideal ruler of the Middle Ages
Authors: Ilyichev Anton Vladimirovich
Published: November 2021

This article is dedicated one of the most remarkable kings of Jerusalem Baldwin IV, also calked the “Leper King”. The goal lies in analyzing the role of Baldwin IV in military-political history of the Kingdom of Jerusalem. The central task is to determine historical veracity of the positive image of Baldwin IV described in literature and cinematography. The historiographical framework is comprised on the works of national and foreign authors devoted to the history of the Latin Kingdom of Jerusalem; works of the Latin chronographers, as well as fragments from Arabic sources that were translated into English by M. C. Lyons and D. E. P. Jackson in their monograph “Saladin: the Politics of the Holy War”. The article raises the question of whether it is possible to advance a thesis that Baldwin IV is the prominent ruler of his time based on the analysis of personal traits and actions. Special attention is given to consideration of the domestic policy of the Kingdom of Jerusalem in the late XII century, as well as relationship of the young king with different political alliances. The conclusion is made that by virtue of his personal traits and actions, Baldwin IV significantly contributed to ensuring security of the Kingdom of Jerusalem. However, serious illness alongside critical internal challenges, led to the siege of Crusader state in the Battle of Hattin. Baldwin IV was unable to prevent it. The personality of Baldwin IV has not previously become the object of separate comprehensive study, which defines the scientific novelty of this paper. The article also views the events that took place in the Kingdom of Jerusalem over the period from 1160 to 1180 from the perspective of personality approach.
ФОРМИ ЕФЕКТИВНОГО УПРАВЛІННЯ ОБ’ЄКТАМИ ЖИТЛОВОЇ НЕРУХОМОСТІ СПІЛЬНОЇ ВЛАСНОСТІ
Authors: Shcherbyna Andrii
Published: November 2021

В умовах зношеності житлового фонду в Україні ефективне управління його збереженням вимагає удосконалення законодавства, а на рівні власників житла – пошуку нових організаційно-правових форм управління багатоквартирними будинками. У статті розглянуто комбінації моделей спільної власності на об’єкти житлової нерухомості з організацією управління без створення та зі створенням юридичної особи. Порівняно з недоліками організації вітчизняних ОСББ проаналізовані дуалістична модель кондомініуму, в якій поєднано спільну власність на будинок і ділянку, індивідуальну власність на квартиру та організаційну форму асоціації власників; унітарна модель асоціації зі спільною власністю на увесь об’єкт нерухомості та правами користування квартирою; фінська унітарна модель житлового підприємства зі створенням товариства з обмеженою відповідальністю. У розглянутих моделях порівняні механізми мобілізації коштів власників та можливості залучення зовнішнього фінансування для здійснення капітальних ремонтів. Зроблені висновки про численні переваги фінської моделі, зокрема для нових склад-них житлових об’єктів та комплексів.
УПРАВЛІННЯ РОЗВИТКОМ РИТЕЙЛ-БРЕНДИНГУ В УМОВАХ ЦИФРОВІЗАЦІЇ ЕКОНОМІКИ
Authors: Hazuda Mykhailo , Stetsiv Myroslava
Published: November 2021

У статті окреслено необхідність створення дієвих управлінських підходів до забезпечення розвитку брендингового середовища, зокрема формування ритейл-брендингу як необхідної маркетингової складової з метою ефективно-го функціонування багатогранних сфер і видів економічної діяльності в умовах посилення процесу цифровізації і трансформаційних змін у межах територіальної економічної системи. Акцентовано увагу на взаємозумовленості та взаємозв’язку між результативністю функціонування галузей економіки і впровадженням цифрових комп’ютерних технологій та формування інтернет-економіки загалом. Зумовлюється пошук механізму впровадження цифрових комунікаційних технологій у напрямі підвищення результативності управлінського процесу у пріоритетних сферах національної економіки і, зокрема, сфери аграрного бізнесу як вагомої складової продовольчої без-пеки країни та її регіонів. Зазначено, що доступ до публічної інформації, глобалізація, оцифрування даних, що поступово проникають в українську економіку, мають позитивний соціальний характер. Обґрунтовано потребу окреслення управлінських підходів до створення ефективної системи організації конкурентоспроможного бізнес-середовища з метою ефективного функціонування економіки країни та її регіонів. Доповнюючим елементом формування результативного управлінського процесу повинно бути спрямування зусиль і поєднання інтересів державних органів влади, органів самоврядування, суб’єктів господарювання і бізнес структур у посиленні цифровізації та впровадженні цифрових комунікаційних технологій у багатогранних сферах і видах економічної діяльності в межах територіальної економічної системи. Доцільним є акцентувати увагу на формування ритейл-брендингу, який в умовах цифрової трансформації є необхідною складовою маркетингової діяльності в жорстких умовах конкурентної боротьби між виробниками продукції за увагу споживача.
INTERNET MEMES IN THE TECHNOLOGY OF TEACHING SPECIAL SUBJECTS AT STATE FIRE ACADEMY OF EMERCOM OF RUSSIA
Authors:   Tutorial internet-portal for professors and teachers Eduneo.ru, Ermolaeva Z. , Gerasimova I. ,   State Fire Academy of EMERCOM of Russia
Published: November 2021

The article presents one of the ways to increase motivation for learning. It implies organization of the learning process taking into account students needs and age peculiarities. This method is part of the modern information environment, namely, Internet memes. This visual element of communication can be widely used in teaching to increase motivation and interest in the discipline being taught.
THE ROLE OF BUDAPEST DISASTER CENTRAL MUSEUM IN TRAINING AND EDUCATING POPULATION
Authors:   Institute of Emergency Situations of Law Enforcement Sciences Department of National University of Public Service Budapest, Hungary, Horvat G. , Berki I. ,   Budapest Disaster Central Museum
Published: November 2021

The authors of the article introduce the experience of cultural, educational work of Budapest Disaster Central Museum. The article presents forms and methods of educating population, primarily the younger generation, and the professional orientation of youth. The authors’ goal is to show the role of the museum in the patriotic education of the younger generation based on the conducted analysis.
Antibacterial therapy of infectious eye diseases
Authors:   Ufa Eye Research Institute, Republic of Bashkortostan, Ufa, Babushkin A. E. , Saitova G. R. ,   Ufa Eye Research Institute, Republic of Bashkortostan, Ufa, Matyukhina E. N. ,   Ufa Eye Research Institute, Republic of Bashkortostan, Ufa
Published: November 2021

The aim of the work was to study the clinical effectiveness of the combined treatment of keratitis and keratoconjunctivitis of bacterial etiology with the combined use of ocomistin eye drops and oftocipro ointment. These drugs were used in complex therapy in 12 patients in the treatment of this ophthalmopathology, which was caused corneal microtrauma after ingestion of foreign bodies or wearing contact lenses. At the same time, in most cases, microflora in the form of staphylococci was detected. Observations of the effectiveness of such a combined treatment for infectious and bacterial lesions of the eye anterior segment showed good tolerability and high (in 11 patients, in 91.7% of cases) clinical effectiveness of this therapy. Key words: bacterial keratitis and keratoconjunctivitis, treatment, antiseptic-okomistin, antibiotic-ciprofloxacin ointment.
Glaucoma is an autoimmune disease
Authors:   I.M. Sechenov First Moscow State Medical University, Moscow, Popova А.А. , Yaremenko T.V. ,   I.M. Sechenov First Moscow State Medical University, Moscow
Published: November 2021

Glaucoma is one of the most serious diseases that affects millions of people around the world, but the pathogenesis of this disease is not completely clear. Once the only mechanism for the development of this disease was considered to be an increase in IOP. Current research indicates that the pathogenesis of glaucoma depends on several interacting mechanisms, which include: mechanical damage due to increased IOP, hypoxia, excitotoxicity, oxidative stress, and the involvement of autoimmune processes. Antibody changes in glaucoma patients have been described, but it is still unclear whether the autoantibodies observed in glaucoma are epiphenomenal or cause of the disease. Key words: glaucoma, glaucoma pathogenesis, autoimmunity, autoimmune glaucoma.
Dry eye syndrome in patients with gout
Authors:   Russian State University of Peoples' Friendship Medical Institute of FSAEIO HE, Mosсow, Odinaeva K.N. , Al Khateeb N.S. ,   Russian State University of Peoples' Friendship Medical Institute of FSAEIO HE, Mosсow, Frolov M.A. ,   Russian State University of Peoples' Friendship Medical Institute of FSAEIO HE, Mosсow
Published: November 2021

Purpose. To determine and study the features of the development of dry eye syndrome (DES) in gout, depending on urate-lowering therapy, the duration of the gout disease and the concentration of uric acid in the tear. Material and methods. The study involved 149 male patients (261 eyes) aged 35 to 75 years (mean age 60.63 ± 11.00 years). Among them, 110 people (202 eyes) with an established diagnosis: "Cataract with concomitant gout disease" and 39 people (59 eyes) with cataracts without clinical and laboratory signs of gout. All patients underwent both standard ophthalmological examinations and special ones. The concentration of uric acid in tears was determined by high performance liquid chromatography (HPLC). The diagnosis of gout was confirmed according to the criteria recommended by ACR / EULAR (2016). Results. In patients with gout who do not take a urate-lowering drug, DES occurs more often (82.1%) than in patients without gout (23.1%). With an increase in the concentration of uric acid in the tear, there is a high tendency to a shortening of the tear film rupture time (strong correlation coefficient r=-0.51, p<0.001) and to a decrease in tear production (Schirmer I test) (strong correlation coefficient r=-0.59, p<0.001). Conclusion. The data obtained indicate clear changes in the functional parameters of total tear production (Schirmer I's test) and the stability of the pre-corneal tear film (Norn's test) in patients with gout. This can be considered as a fact of the predisposition of this category of patients to the development of DES. A strong dependence of changes in tear production and HRVP on the concentration of uric acid in the tear was established. There is an obvious need for additional examination of this category of patients and an adequate choice of therapy, as well as the timely appointment of "artificial tear" drugs. Key words: dry eye syndrome, uric acid, gout.
Antigen cross-presentation by macrophages
Authors: Малышев И.Ю. , Кузнецова Л.В. , Чернышова О.О. , Буданова О.П. , Бахтина Л.Ю.
Published: November 2021

В обзоре рассматриваются механизмы кросс-презентации антигена и особенности этого процесса в макрофагах. Представлено сравнение особенностей кросс-презентации в дендритных клетках и разных фенотипах макрофагов. Описаны пути кросс-презентации -протеасомный и вакуолярный. Протеасомный путь состоит из следующих стадий: 1) захват антигена в фагосому; 2) сохранение антигена в фагосоме; 3) перенос антигена в цитозоль и его расщепление в протеасоме до олигопептидов; 4) перенос олигопептидов в компартменты, содержащие главный комплекс гистосовместимости I типа (major histocompatibility complex I, MHC I); 5) загрузка олигопептида на MHC-I и перенос на поверхность клетки. Вакуолярный путь начинается сходно с протеасомным, но отличается в том, что захваченный антиген не покидает фагосому, а там же расщепляется и нагружается на MHC-I. Макрофаги могут использовать любой из этих путей. Макрофаги, происходящие из моноцитов крови, используют вакуолярный путь, макрофаги красной пульпы селезенки - протеасомный, а перитонеальные - и тот, и другой. Эффективность кросс-презентации макрофагов зависит от его тканевого типа. При разработке методов иммунотерапии, основанной на макрофагах, важно понимать стадии обоих путей кросс-презентации, поскольку каждая из них может рассматриваться как мишень для повышения эффективности кросс-презентации антигена и соответственно, эффективности иммунотерапии рака.

This review focuses on mechanisms of antigen cross-presentation and features of this process in macrophages. Features of the cross-presentation in dendritic cells and in various macrophage phenotypes are compared. The cross-presentation can be the result of either the proteasomal or vacuolar pathway. The proteasomal pathway includes the following stages: 1) antigen capture into the phagosome; 2) antigen preservation in the phagosome; 3) antigen transfer to the cytosol and its cleavage in the proteasome to oligopeptides; 4) oligopeptide transfer into major histocompatibility complex (MHC) I-containing compartments; 5) oligopeptide loading onto the MHC I and transferring it to the cell surface. The vacuolar pathway begins in a similar way as the proteasomal pathway but differs in that the captured antigen does not leave the phagosome, but is cleaved there and loaded onto MHC I. Macrophages can use any of these pathways. Macrophages originating from blood monocytes use the vacuolar pathway; macrophages of the red pulp of the spleen use the proteasomal pathway, and peritoneal macrophages use both. The effectiveness of cross-presentation of macrophages depends on the macrophage tissue type. When developing macrophage-based methods of immunotherapy, it is important to understand the stages of both cross-presentation pathways since each of them can be considered as a target for increasing the efficiency of antigen cross-presentation and, accordingly, the effectiveness of cancer immunotherapy.