bluuebunny/crossref_metadata_2025 huggingface dataset:
La « voie révolutionnaire » de Salvador Allende (1970-1973) et les limites de l’engagement soviétique en Amérique latine
Authors: Pedemonte Rafael
Published: September 2018

Loin d’entraîner un tournant radical dans les relations Chili-URSS, les Soviétiques restent prudents vis-à-vis de la « voie vers le socialisme » indiquée par Salvador Allende. Dans un cadre international marqué par des efforts de rapprochement Est-Ouest et des difficultés économiques grandissantes, Moscou ne souhaite pas faire du gouvernement de l’Unité populaire un « second Cuba ». Outre ces considérations géostratégiques, ses réticences s’expliquent par ses doutes sur la viabilité d’une « révolution pacifique » menée dans le cadre de la « démocratie bourgeoise ». Les tensions engendrées par le « défi » des Cubains, qui contestent entre 1962 et 1968 le principe de la « coexistence pacifique », découragent les décideurs du Kremlin, peu enclins à assumer de nouveaux paris dans un territoire dominé par la présence incontournable des États-Unis.
 Cuidado centrado na família em Unidade de Terapia Intensiva Neonatal e Pediátrica: visão do enfermeiro/ Family-centered care in Neonatal and Pediatric Intensive Care Unit: nurse's vision
Authors: Felipin Larissa Carolina Segantini , Merino Maria De Fátima Garcia Lopes , Baena Juliane Ayres , Oliveira Rafaela B. S. R. , Borghesan Nataly Barbosa Alves , Higarashi Ieda Harumi
Published: September 2018

O Cuidado Centrado na Família é uma filosofia que reconhece a família como parte fundamental do cuidado, com o objetivo de participação no planejamento das ações em saúde. Este estudo teve como objetivo conhecer a visão de enfermeiros de uma unidade de terapia intensiva neonatal e pediátrica a respeito do Cuidado Centrado na Família. Estudo descritivo qualitativo, com referencial teórico do Cuidado Centrado na família, realizado no ano de 2015 em uma Unidade de Terapia Intensiva Neonatal-Pediátrica de um hospital privado. Participaram do estudo dezenove enfermeiras. Os relatos foram submetidos à análise temática e dessa análise emergiram duas categorias temáticas: “O Cuidado Centrado na Família na percepção do enfermeiro que presta cuidados intensivos à criança” e “Os desafios da incorporação do Cuidado Centrado na Família na prática diária: lacuna entre teoria e prática”. O estudo revelou a persistência de lacunas entre a teoria e a prática do Cuidado Centrado na Família, sendo este encarado como um ideal almejado pelos profissionais, mas ainda distante de ser plenamente compreendido e alcançado, em razão de obstáculos organizacionais e formativos. O regaste conceitual é necessário para promover reflexões acerca da viabilidade deste modelo, evidenciando seu potencial na qualificação da assistência, tornando-a mais holística e humanizada.
Revision of the taxonomy and distribution of the NeotropicalCopris incertusspecies complex (Coleoptera: Scarabaeidae: Scarabaeinae)
Authors: Darling James D.G. , Génier François
Published: September 2018

Copris incertusSay, 1835 (Coleoptera: Scarabaeidae: Scarabaeinae: Coprini) has been described as a New World coprophagous scarab distributed from Mexico to Ecuador with large discontinuities in its range between the Yucatán province and Costa Rica. TheC. incertusspecies complex of theCopris minutus(Drury, 1773) species group consists ofC. incertus,Copris laevicepsHarold, 1869, andCopris lugubrisBoheman, 1858. Based on external morphology and male genitalia, we discovered that multiple species have been classified asC. incertus.Of these species, five are new:Copris amazonicusnew species,Copris brevicornisnew species,Copris davidinew species,Copris moroninew species, andCopris susanaenew species. Herein, we revise the organisation of theC.incertusspecies complex and propose a new species complex, theC. laevicepsspecies complex, which includes:C. davidi,Copris igualensisWarner, 1990, andC. laeviceps, formerly included in theC. incertusspecies complex. We provide an identification key along with species distribution maps, images of habitus, and diagnostic characters.
Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis
Authors: Hawkes Jason E. , Yan Bernice Y. , Chan Tom C. , Krueger James G.
Published: September 2018

Psoriasis vulgaris is a common, heterogeneous, chronic inflammatory skin disease characterized by thickened, red, scaly plaques and systemic inflammation. Psoriasis is also associated with multiple comorbid conditions, such as joint destruction, cardiovascular disease, stroke, hypertension, metabolic syndrome, and chronic kidney disease. The discovery of IL-17–producing T cells in a mouse model of autoimmunity transformed our understanding of inflammation driven by T lymphocytes and associations with human inflammatory diseases, such as psoriasis. Under the regulation of IL-23, T cells that produce high levels of IL-17 create a self-amplifying, feed-forward inflammatory response in keratinocytes that drives the development of thickened skin lesions infiltrated with a mixture of inflammatory cell populations. Recently, the Food and Drug Administration approved multiple highly effective psoriasis therapies that disrupt IL-17 (secukinumab, ixekizumab, and brodalumab) and IL-23 (guselkumab and tildrakizumab) signaling in the skin, thus leading to a major paradigm shift in the way that psoriatic disease is managed.
The Intestinal Virome and Immunity
Authors: Neil Jessica A. , Cadwell Ken
Published: September 2018

The composition of the human microbiome is considered a major source of interindividual variation in immunity and, by extension, susceptibility to diseases. Intestinal bacteria have been the major focus of research. However, diverse communities of viruses that infect microbes and the animal host cohabitate the gastrointestinal tract and collectively constitute the gut virome. Although viruses are typically investigated as pathogens, recent studies highlight a relationship between the host and animal viruses in the gut that is more akin to host–microbiome interactions and includes both beneficial and detrimental outcomes for the host. These viruses are likely sources of immune variation, both locally and extraintestinally. In this review, we describe the components of the gut virome, in particular mammalian viruses, and their ability to modulate host responses during homeostasis and disease.
Paleoceanography and ice sheet variability offshore Wilkes Land, Antarctica – Part 3: Insights from Oligocene–Miocene TEX86-based sea surface temperature reconstructions
Authors: Hartman Julian D. , Sangiorgi Francesca , Salabarnada Ariadna , Peterse Francien , Houben Alexander J. P. , Schouten Stefan , Brinkhuis Henk , Escutia Carlota , Bijl Peter K.
Published: September 2018

Abstract. The volume of the Antarctic continental ice sheet(s) varied
substantially during the Oligocene and Miocene (∼34–5 Ma) from smaller
to substantially larger than today, both on million-year and on orbital
timescales. However, reproduction through physical modeling of a dynamic
response of the ice sheets to climate forcing remains problematic, suggesting
the existence of complex feedback mechanisms between the cryosphere, ocean, and
atmosphere systems. There is therefore an urgent need to improve the models
for better predictions of these systems, including resulting potential future
sea level change. To assess the interactions between the cryosphere, ocean, and
atmosphere, knowledge of ancient sea surface conditions close to the
Antarctic margin is essential. Here, we present a new TEX86-based sea
surface water paleotemperature record measured on Oligocene sediments from
Integrated Ocean Drilling Program (IODP) Site U1356, offshore Wilkes Land,
East Antarctica. The new data are presented along with previously published
Miocene temperatures from the same site. Together the data cover the
interval between ∼34 and ∼11 Ma and encompasses two hiatuses. This
record allows us to accurately reconstruct the magnitude of sea surface
temperature (SST) variability and trends on both million-year and
glacial–interglacial timescales. On average, TEX86 values indicate SSTs
ranging between 10 and 21 ∘C during the Oligocene and Miocene, which
is on the upper end of the few existing reconstructions from other
high-latitude Southern Ocean sites. SST maxima occur around 30.5, 25, and
17 Ma. Our record suggests generally warm to temperate ocean offshore Wilkes
Land. Based on lithological alternations detected in the sedimentary record,
which are assigned to glacial–interglacial deposits, a SST variability of
1.5–3.1 ∘C at glacial–interglacial timescales can be established.
This variability is slightly larger than that of deep-sea temperatures
recorded in Mg ∕ Ca data. Our reconstructed Oligocene temperature
variability has implications for Oligocene ice volume estimates based on
benthic δ18O records. If the long-term and orbital-scale SST
variability at Site U1356 mirrors that of the nearby region of deep-water
formation, we argue that a substantial portion of the variability and trends
contained in long-term δ18O records can be explained by variability
in Southern high-latitude temperature and that the Antarctic ice volume may
have been less dynamic than previously thought. Importantly, our temperature
record suggests that Oligocene–Miocene Antarctic ice sheets were generally of
smaller size compared to today.
Light absorption by marine cyanobacteria affects tropical climate
mean state and variability
Authors: Paulsen Hanna , Ilyina Tatiana , Jungclaus Johann H. , Six Katharina D. , Stemmler Irene
Published: September 2018

Abstract. Observations indicate that positively buoyant marine cyanobacteria, which are abundant throughout the tropical and subtropical ocean, have a strong local heating effect due to light absorption at the ocean surface. How these local changes in radiative heating affect the climate system on the large scale is unclear as of yet. We use the Max Planck Institute Earth System Model (MPI-ESM) and find that – in contrast to the heating effect which was reported in previous studies – cyanobacteria have a considerable cooling effect on tropical climatological sea surface temperature (SST) in the order of 0.5 K. This cooling is caused by local shading of subtropical subsurface water that is upwelled at the equator and in eastern boundary upwelling systems. Implications for the climate system include an expansion of the Hadley cells and a westward shift of the Walker circulation. The amplitude of the seasonal cycle of SST is increased in large parts of the tropical ocean by up to 25 %, and the tropical Pacific interannual variability is enhanced by ∼ 20 %. This study emphasizes the sensitivity of the tropical climate system to light absorption by the specific phytoplankton group of cyanobacteria due to its regulative effect on tropical SST. Generally, including the phytoplankton-dependent light attenuation instead of a globally uniform attenuation depth improves some of the major model temperature biases, indicating the relevance of taking into account this bio-physical feedback in climate models.
Clast imbrication in coarse-grained mountain streams and stratigraphic archives as indicator of deposition in upper flow regime conditions
Authors: Schlunegger Fritz , Garefalakis Philippos
Published: September 2018

Abstract. Clast imbrication is one of the most conspicuous sedimentary structures in coarse-grained clastic deposits of modern rivers but also in the stratigraphic record. In this paper, we test whether the formation of this fabric can be related to the occurrence of upper flow regime conditions in streams. To this end, we calculated the Froude number at the incipient motion of coarse-grained bedload for various values of relative bed roughness and stream gradient as these are the first-order variables that can practically be extracted from preserved deposits. We found that a steeper energy gradient, or slope, and a larger bed roughness tend to favor the occurrence of supercritical flows. We also found that, at the onset of grain motion, the ratio ϕ between the critical shear stress for the entrainment of a sediment particle and its inertial force critically controls whether flows tend to be super- or subcritical during entrainment. We then mapped the occurrence of clast imbrication in Swiss streams and compared these data with the hydrologic calculations. Results indicate that imbrication may record supercritical flows provided that (i) ϕ values are larger than ca. 0.05, which is appropriate for streams in the Swiss Alps; (ii) average stream gradients exceed ca. 0.5 ± 0.1°; and (iii) relative bed roughness values, i.e., the ratio between water depth d and bed sediment D84, are larger than  ∼ 0.06 ± 0.01. We cannot rule out that imbrication may be formed during subcritical flows with ϕ values as low as 0.03, as demonstrated in a large number of flume experiments. However, our results from Alpine streams suggest that clast imbrication likely reflects upper flow regime conditions where clasts form well-sorted and densely packed clusters. We consider that these differences may be rooted in a misfit between the observational and experimental scales.
Spatially dependent Intensity-Duration-Frequency curves
to support the design of civil infrastructure systems
Authors: Le Phuong Dong , Leonard Michael , Westra Seth
Published: September 2018

Abstract. Conventional flood risk methods typically focus on estimation at a single location, which is inadequate for civil infrastructure systems such as road or railway infrastructure. This is because rainfall extremes are spatially dependent, so that to understand overall system risk it is necessary to assess the interconnected elements of the system jointly. For example, when designing evacuation routes it is necessary to understand the risk of one part of the system failing given that another region is flooded or exceeds the level at which evacuation becomes necessary. Similarly, failure of any single part of a road section (e.g., a flooded river crossing) may lead to the wider system’s failure (i.e. the entire road becomes inoperable). This study demonstrates a spatially dependent Intensity-Duration-Frequency curve framework that can be used to estimate flood risk across multiple catchments, accounting for dependence both in space and across different critical storm durations. The framework is demonstrated via a case study of a highway upgrade, comprising five bridge crossings where the upstream contributing catchments each have different times of concentration. The results show that conditional and unconditional design flows can differ by a factor of two, highlighting the importance of taking an integrated approach. There is also a reduction in the failure probability of the overall system compared with the case of no spatial dependence between storms. The results demonstrate the potential uses of spatially dependent Intensity-Duration-Frequency curves and suggest the need for more conservative design estimates to take into account conditional risks.
The importance of city trees for reducing net rainfall: comparing
measurements and simulations
Authors: Smets Vincent , Wirion Charlotte , Bauwens Willy , Hermy Martin , Somers Ben , Verbeiren Boud
Published: September 2018

Abstract. An in-situ tree interception experiment was conducted to determine the hydrological impact of a solitary standing Norway maple and small-leaved lime in an urban environment. During the two-year experiment, rainfall data was collected and divided into interception, throughfall and stemflow. With approximately 38 % of the gross precipitation intercepted by both trees, the interception storage was higher than for similar studies done in Mediterranean regions. A regression analyses for the Norway maple found rainfall duration, rainfall amount and the tree's leaf area index to be the most important variables influencing interception storage. The regression analysis and the tree interception models by Gash and Rutter, as well as an adapted version of the Water and Energy Transfer between Soil, Plants and Atmosphere model (WetSpa), were tested for their accuracy in modelling the measured interception storage. The models in general overestimated interception storage for small interception events ( interception storage). The regression analysis wasn't stable throughout seasons, event sizes and trees making it unsuitable for generic use. The method of Gash slightly overperformed WetSpa and Rutter for all events throughout seasons and trees. However, WetSpa showed a better performance for rainfall events > 10 mm. A scenario analysis, featuring the construction of student houses on a university campus, demonstrated the potential of urban trees to retain rainfall water. Even though trees alone could not restore the natural hydrological balance, they could partly mitigate the increased runoff volume and peak discharge caused by sealing of the natural surface through decreasing the net rainfall that reaches the ground. This study highlights the role of solitary trees in an urban environment where natural hydrological processes are severely altered.
Local and remote moisture sources for extreme precipitation: a
study of the two famous 1982 Western Mediterranean episodes
Authors: Insua-Costa Damián , Miguez-Macho Gonzalo , Llasat María Carmen
Published: September 2018

Abstract. Floods and flash floods are frequent in the South of Europe resulting from heavy rainfall events that often produce more than 200 mm in less than 24 h. Even though the meteorological conditions favorable for these situations have been widely studied, there is a lingering question that still arises: which are the sources of humidity that could explain so much precipitation? To answer this question, the regional atmospheric Weather Research and Forecasting (WRF) Model with a recently implemented moisture tagging capability has been used to analyze the main moisture sources in two famous flood events occurred during the autumn of 1982 (October and November) in the Western Mediterranean area, which is regularly affected by this type of adverse weather episodes. The procedure consists in selecting a priori potential moisture source regions for the considered extreme event, and then performing simulations with the tagging technique to quantify the relative contribution of each selected source to total precipitation. For these events we study the influence of four possible potential sources: 1) evaporation in the Western Mediterranean; 2) evaporation in the Central Mediterranean; 3) evaporation in the North Atlantic; 4) advection from the tropical and subtropical Atlantic and Africa. Results show that these four moisture sources explain most of the accumulated precipitation, with the tropical and subtropical input being the most relevant in both cases. In the October event, evaporation in the Western and Central Mediterranean and in the North Atlantic also had an important contribution. In the November episode, however, tropical and subtropical moisture accounted for more than half of the total accumulated rainfall, while evaporation in the Western Mediterranean and North Atlantic played a secondary role and the contribution of the Central Mediterranean was almost negligible. Remote sources were therefore crucial: in the October event they played a similar role to local sources while in the November case they were clearly dominant. In both episodes, long distance moisture transport from the tropics and subtropics occurred mostly in mid tropospheric layers, through well-defined moisture plumes with maximum mixing ratios at medium levels.
Climatic responses to systematic time variations of parameters: a dynamical approach
Authors: Nicolis Catherine
Published: September 2018

Abstract. The climatic response to time-dependent parameters is revisited from a
nonlinear dynamics perspective. Some general trends are identified, based on
a generalized stability criterion extending classical stability analysis to
account for the presence of time-varying coefficients in the evolution
equations of the system's variables. Theoretical predictions are validated by
the results of numerical integration of the evolution equations of
prototypical systems of relevance in atmospheric and climatic dynamics.
Opaque Selves: A Ricœurian Response to Galen Strawson’s Anti- Narrative Arguments
Authors: Arca Kristofer Camilo
Published: September 2018

As narrative conceptions of selfhood have gained more acceptance within various disciplines including philosophy, psychology, and the cognitive sciences, so too have these conceptions been critically appraised. Chief among those who are suspicious of the overall viability of ‘narrative identity’ is the philosopher, Galen Strawson. In this paper, I develop five arguments underlying Strawson’s critique of narrative identity, and respond to each argument from the perspective of the hermeneutic phenomenology of Paul Ricœur. Though intuitive, I demonstrate that none of Strawson’s arguments are cogent. The confrontation between these two figures highlights a deep conceptual disagreement about our epistemic access to the self, which has thus far gone unrecognized in the Anglo-American discussion, so that it raises a new problem for the metaphysics of personal identity.
Introduction
Authors: Thiriez-Arjangi Azadeh , Arel Stephanie
Published: September 2018

Repenser L'idéologie et l'utopie, 30 ans après
Sentiment Protocol: A Decentralized Protocol Leveraging Crowdsourced Wisdom
Authors: Muehlemann Anton
Published: September 2018

The wisdom of the crowd is a valuable asset in today’s society. It is not only important in predicting elections but also plays an essential role in marketing and the financial industry. Having a trustworthy source of opinion can make forecasts more accurate and markets predictable. Until now, a fundamental problem of surveys is the lack of incentives for participants to provide accurate information. Classical solutions like small monetary rewards or the chance of winning a prize are often not very attractive for participants. More attractive solutions, such as prediction markets, face the issue of illegality and are often unavailable. In this work, we present a solution that unites the advantages from classical polling and prediction markets via a customizable incentivization framework. Apart from predicting events, this framework can also be used to govern decentralized autonomous organizations.
Sistema de ventas para librería Sánchez, Siuna, 2016
Authors: Garzón Díaz Walter , Reyes Macís Griselda , Salazar Solano Frank Robing
Published: September 2018

Este estudio se realizó en librería Sánchez, ubicada en el barrio “Pedro Joaquín Chamorro” sector 3 de la ciudad de Siuna-RACCN, Nicaragua. El objetivo fue desarrollar un sistema de control de ventas e inventario; para esto se realizó una base de datos, para el registro de entradas y salidas de los productos del negocio, además se diseñó una interfaz que permite al usuario interactuar con la información almacenada en la base de datos y posteriormente la implementación del sistema. El estudio fue aplicativo desde el paradigma cuantitativo. Se desarrolló el sistema y se implementó en la librería Sánchez. El sistema permite a los usuarios, ingresar datos de todos los productos y sus categorías, clientes, proveedores existentes, además facilita las gestiones de ventas y compras.
Complejidad y sostenibilidad de dos agroecosistemas con cacao, Siuna 2017
Authors: Altamirano Hernández Iris Jamileth , Amador López Mario Feliciano , Montalván Castellón Oscar
Published: September 2018

Esta investigación se realizó en la comunidad El Carao-Hormiguero, Siuna, 2017, en las fincas Los Laureles del Sr. German Valerio Pérez y El Encanto del Sr. Carlos López Lagos, con el fin de evaluar la complejidad y sostenibilidad de dos agro ecosistemas con cacao a través de manejo de biodiversidad en los agroecosistemas y determinar el nivel de sostenibilidad en el aspecto sociocultural, económico y agro-ambiental. Se aplicaron dos metodologías, Vázquez (2013) la cual evalúa seis indicativos y 64 indicadores, se miden con un rango de (0-4) siendo este un valor estándar para medir el nivel de complejidad de los sistemas de producción y HESOFI (2015) que evalúa 71 indicadores, 12 componentes y 3 criterios, sociocultural, económicos y agro-ambiental y para cada criterio se asigna un valor de 100. El coeficiente y manejo de la biodiversidad en la finca Los Laureles es medianamente complejo con un nivel del 2.61 (56.71%) con un índice satisfactorio y El Encanto 1.60 (33.44%), determinándose como un sistema de producción poco complejo con índice medianamente satisfactorio. El nivel de sostenibilidad que miden las dimensiones socio-cultural, económica y agro-ambiental para la finca El Encanto fue de 132 de 300, su fuerza radica en lo sociocultural con (66%), agro-ambiental con (41%) y económico con un (25%). Los Laureles presentó un valor de 202 de 300, su mayor fuerte fue lo sociocultural (75%), lo agro- ambiental (69%) y lo económico (58%). Tales resultados indican que Los Laureles cuenta con un grado de sostenibilidad del (67.40%), y El Encanto con (44.19%).
Revisitando os pressupostos da juristocracia à brasileira: mobilização judicial na Assembleia Constituinte e o fortalecimento do Supremo Tribunal Federal
Authors: Lima Flávia Danielle Santiago
Published: September 2018

O trabalho volta-se aos pressupostos da judicialização da política no Brasil, ao questionar os fatores, na Assembleia Nacional Constituinte (1987-1988), que permitiram a expansão do papel institucional do Supremo Tribunal Federal (STF) na futura ordem constitucional. A partir do método dedutivo, parte-se da contribuição de Ran Hirschl (2004), que explica o fortalecimento das cortes, num movimento mundial de relevância dos tribunais, diante das dinâmicas entre os grupos de poder, em sua confiança de que a “juristocracia” lhes seria mais favorável no futuro (autopreservação hegemônica). O autor destaca o papel dos membros das elites jurídicas e judiciais, como parte relevante nesses processos, em sua pretensão de incrementar seu poder e/ou obter reputação internacional. O estudo de caso brasileiro é amparado na revisão de literatura sobre a transição democrática e o processo constituinte, além de pesquisa documental, para identificar a participação, influências e dissensos entre juristas e ministros do STF durante a assembleia, especialmente na Subcomissão do Poder Judiciário e do Ministério Público.
Analyzing the Potential Economic Value of Energy Storage
Authors: Giulietti Monica , Grossi Luigi , Baute Elisa Trujillo , Waterson Michael
Published: September 2018

This paper examines the commercial opportunities for electrical energy storage, taking market prices as given and determining the extent to which a strategy of arbitrage across the day, buying at the lowest price times at night and selling at the highest price times during the early evening, and relying on price forecasts one day-ahead generates profits in the British context. The paper sets out the potential problems as the market moves to absorb increasing amounts of wind, then characterises the nature of prices, which reveals the importance of a strategy in which power is absorbed into store for a relatively few hours of the day and discharged over a relatively few hours. It argues that additional incentives may need to be put into place in order to render storage over relatively longer periods more attractive and to deliver broader social benefits which are unlikely to be generated and captured as a result of purely commercial considerations.
Ontslag van statutair bestuurders – een recap
Authors: Attaïbi A.
Published: September 2018

Ontslag van statutair bestuurders – een recap

In deze bijdrage bespreekt de auteur het ontslag van bestuurders vanuit vennootschapsrechtelijk en arbeidsrechtelijk perspectief, waarbij recente wetgeving, rechtspraak en literatuur de revue passeren. Meer in het bijzonder gaat de auteur in op de (ver)nietig(baar)heid van ontslagbesluiten, het arbeidsrechtelijk vereiste van een ‘redelijke grond’ voor ontslag en hoe dit zich verhoudt tot de vennootschapsrechtelijke ‘te allen tijde’-ontslagbevoegdheid van de aandeelhoudersvergadering, alsook (de begroting van) de billijke vergoeding aan bestuurders.
Arqueología de la interactividad: el libro móvil y pop-up como antecedente de los videojuegos
Authors: Cuadrado Alvarado Alfonso
Published: September 2018

Este trabajo se centra en un terreno escasamente explorado: los antecedentes culturales del videojuego. Más allá de las referencias a los juegos tradicionales, deportivos o de mesa, las tecnologías digitales e incluso mecánicas que se muestran como antecesores directos (computadoras o pinballs) del videojuego responden a una larga tradición que hunde sus raíces en los espectáculos populares de los siglos xviii y xix. Su nacimiento como medio con gran capacidad de hibridación cultural tiene un paralelismo con el del libro móvil y desplegable. El libro tradicional evoluciona como soporte para sintetizar, en una única experiencia, las nuevas formas de entretenimiento como el panorama, las fantasmagorías, los espectáculos de marionetas y autómatas, el peep show, los dioramas y las ilusiones ópticas de zootropos o linternas mágicas. Mediante una técnica nueva como es la ingeniería de papel, que emula la mecánica del autómata, rompe la inmovilidad de la imagen permitiendo las primeras animaciones de personajes asociadas a un relato y la construcción de un espacio tridimensional explorable. El lector interviene por primera vez en el proceso de la narración, interactuando con las partes móviles y componiendo un mundo de ficción sobre la base de su actividad y de las nuevas relaciones entre texto e imagen, distintas a las que mantenían en el libro ilustrado. Se crea por primera vez un artefacto lúdico distinto al juguete tradicional, en un proceso muy similar al que dará lugar al juego electrónico cien años después. La evolución de ambos soportes conlleva soluciones de desarrollo similares en cuanto a técnicas de animación, creación del punto de vista o a la relación entre la narración y la interacción. El artículo revela, como conclusión, el permanente vínculo de los videojuegos con la herencia lúdica del siglo xix y cómo este influjo vuelve al espectáculo de la mano de la realidad virtual.
PONAŠANJE ''MILENIJACA'' KAO POTROŠAČA
Authors: Bobrek Macanović Kristina
Published: September 2018

Brz rast digitalnih tehnologija i interneta je donio trendove u marketingu koji podrazumijevaju promjene na gotovo dnevnoj bazi, i prilagođavanje kompanija i njihovih marketinških komunikacija na svim nivoima, kako u načinima interne, tako i eksterne komunikacije. Poseban uticaj na ove promjene imaju nove generacije, tzv. „milenijalci” (rođeni od osamdesetih do dvehiljaditih godina) koji pokazuju neke potpuno specifične osobine u odnosu na prethodnu, „generaciju iks” (ljudi rođeni šezdesetih i sedamdesetih). Kompanije koje uspiju da ih razumiju i prilagode se njihovim osobinama, uspješnije će ostvarivati svoje ciljeve, bilo da se radi o profitnim ili neprofitnim organizacijama. Upravo zbog toga, cilj ovog rada je da istakne osobine milnenijalaca kao potrošača koje imaju uticaja na kreiranje i realizaciju marketinških aktivnosti u kompanijama. U radu su korišteni rezultati istraživanja koji su dobijeni metodama analize sekundarnih izvora, te primarnih izvora kroz tehnike anketiranja i semnatičkog diferencijala.
EKONOMSKA NEJEDNAKOST ZEMALJA EVROPSKE UNIJE
Authors: Pantović Stanislav
Published: September 2018

Globalna ekonomska kriza je otkrila strukturne slabosti privreda i nedostatke ekonomskih politika razvijenih zemalja i zemalja u razvoju, uključujući zemlje centralne, istocne i jugoistocne Evrope koje su registrovale dubok realni pad BDP u 2009. nakon prethodnog višegodišnjegprivrednog rasta u proseku između 5% i 6%. Kod mnogih zemalja u razvoju je smanjena kupovna moć plata i penzija i investicioni kapacitet. U takvoj ekonomskoj situaciji zemlje ovog regiona su zatražile stranu finansijsku pomoć, budući da budžetski resursi i raspoloživipriliv stranog kapitala nisu mogli da ublaže krizu. Pri tome, mnoge zemlje su antikrizniprogram primenile sa zakašnjenjem, a neke zemlje su pružile pomoćprivredi i stanovništvu brzo i koordinirano. MMF i EU su program krizne pomoćipružale svojim clanicama u skladu sa utvrđenim kriterijumima. Ekonomska nejednakost i kriza imaju međusobno povratno dejstvo. Sa jedne strane visoka stopa nejednakosti može biti posledica delovanja negativnih ekonomskih faktora, dok sa druge produbljuje i produžava krizu u kojoj se država nalazi. Razlog za to je što nejednaka društva ne mogu istovremeno biti i efikasna, a njihove ekonomije stabilne i održive na duži vremenski period. Isto se odnosi i na društva u kojima se one stvaraju. Negativne ekonomske posledice nejednakosti se mogu prve uociti.
Testing the FAIR metrics on data catalogs
Authors: van Erp Jarno A A , Langen Carolyn D , Boon Anca , van Bochove Kees
Published: September 2018

The introduction of the FAIR –Findable, Accessible, Interoperable, Reusable– principles has caused quite an uproar within the scientific community. Principles which, if everyone adheres to them, could result in new, revolutionary ways of performing research and fulfill the promise of open science. Furthermore, it allows for concepts such as personalized medicine and personal health monitoring to -finally- become implemented in daily practice.

However, to bring about these changes, data users need to rethink the way they treat scientific data. Just passing a dataset along, without extensive metadata will not suffice anymore. Such new ways of executing research require a significantly different approach from the entire scientific community or, for that matter, anyone who wants to reap the benefits from going FAIR.

Yet, how do you initiate behavioral change? One important solution is by changing the software scientists use and requiring data owners, or data stewards, to FAIRify their dataset. Data catalogs are a great starting point for FAIRifying data as the software already intends to make data Findable and Accessible, while the metadata is Interoperable and relying on users to provide sufficient metadata to ensure Reusability. In this paper we analyse how well the FAIR principles are implemented in several data catalogs.

To determine how FAIR a catalog is, the FAIR metrics were created by the GO-FAIR initiative. These metrics help determine to what extend data can be considered FAIR. However, the metrics were only recently developed, being first released at the end of 2017. At the moment software does not come standard with a FAIR metrics review. Still, this insight is highly desired by the scientific community. How else can they be sure that (public) money is spend in a FAIR way?

The Hyve has tested/evaluated three popular open source data catalogs based on the FAIR metrics: CKAN, Dataverse, and Invenio. Most data stewards will be familiar with at least one of these.

Within this white paper we provide answers to the following questions:

Which of the three data catalogs performs best in making data FAIR?

Which data catalog utilizes FAIR datasets the most?

Which one creates the most FAIR metadata?

Which catalog has the highest potential to increase its FAIRness, and how?

Which data catalog facilitates the FAIRifying process the best?
Forest floor temperature and greenness link significantly to canopy attributes in South Africa’s fragmented coastal forests
Authors: Pfeifer Marion , Boyle Michael JW , Dunning Stuart , Olivier Pieter
Published: September 2018

Tropical landscapes are changing rapidly due to changes in land use and land management. Being able to predict and monitor land use change impacts on species for conservation or food security concerns requires the use of habitat quality metrics, that are consistent, can be mapped using above - ground sensor data and are relevant for species performance. Here, we focus on ground surface temperature (Thermalground) and ground vegetation greenness (NDVIdown) as potentially suitable metrics of habitat quality. We measure both across habitats differing in tree cover (natural grassland to forest edges to forests and tree plantations) in the human-modified coastal forested landscapes of Kwa-Zulua Natal, South Africa. We show that both habitat quality metrics decline linearly as a function of increasing canopy closure (FCover, %) and canopy leaf area index (LAI). Opening canopies by about 20% or reducing canopy leaf area by 1% would result in an increase of temperatures on the ground by more than 1°C, and an increase in ground vegetation greenness by 0.2 and 0.14 respectively. Upscaling LAI and FCover to develop maps from Landsat imagery using random forest models allowed us to map Thermalground and NDVIdown using the linear relationships. However, map accuracy was constrained by the predictive capacity of the random forest models predicting canopy attributes and the linear models linking canopy attributes to the habitat quality metrics. Accounting for micro-scale variation in temperature is seen as essential to improve biodiversity impact predictions. Our upscaling approach suggests that mapping ground surface temperature based on radiation and vegetation properties might be possible, and that canopy cover maps could provide a useful tool for mapping habitat quality metrics that matter to species. However, we need to increase sampling of surface temperature spatially and temporally to improve and validate upscaled models. We also need to link surface temperature maps to demographic traits of species of different threat status or functions in landscapes with different disturbance and management histories testing for generalities in relationships. The derived understanding could then be exploited for targeted landscape restoration that benefits biodiversity conservation and food security sustainably at the landscape scale.
Multifunctional roles of Tropomodulin-3 in regulating actin dynamics
Authors: Parreno Justin , Fowler Velia M
Published: September 2018

Tropomodulins (Tmods) are proteins that cap the slow growing (pointed) ends of actin filaments (F-actin). The basis for our current understanding of Tmod function comes from studies in cells with relatively stable and highly organized F-actin networks, leading to the view that Tmod capping functions principally to preserve F-actin stability. However, not only is Tmod capping dynamic, but it also can play major roles in regulating diverse cellular processes involving F-actin remodeling. Here, we highlight the multifunctional roles of Tmod with a focus on Tmod3. Like other Tmods, Tmod3 binds tropomyosin (Tpm) and actin, capping pure F-actin at submicromolar and Tpm-coated F-actin at nanomolar concentrations. Unlike other Tmods, Tmod3 can also bind actin monomers and its ability to bind actin is inhibited by phosphorylation of Tmod3 by Akt2. Tmod3 is ubiquitously expressed and present in a diverse array of cytoskeletal structures, including contractile structures such as sarcomere-like units of actomyosin stress fibers and in the F-actin network encompassing adherens junctions. Tmod3 participates in F-actin network remodeling in lamellipodia during cell migration, and in the assembly of specialized F-actin networks during exocytosis. Furthermore, Tmod3 is required for development, regulating F-actin mesh formation during meiosis I of mouse oocytes, erythroblast enucleation in definitive erythropoiesis, and megakaryocyte morphogenesis in the mouse fetal liver. Thus, Tmod3 plays vital roles in dynamic and stable F-actin networks in cell physiology and development, with further research required to delineate the mechanistic details of Tmod3 regulation in the aforementioned processes, or in other yet to be discovered processes.
Poor coherence in older people's speech is explained by impaired semantic and executive processes
Authors: Hoffman Paul , Loginova Ekaterina , Russell Asatta
Published: September 2018

The ability to speak coherently is essential for effective communication but declines with age: older people more frequently produce tangential, off-topic speech. The cognitive factors underpinning this decline are poorly understood. We predicted that maintaining coherence relies on effective regulation of activated semantic knowledge about the world, and particularly on the selection of currently relevant semantic representations to drive speech production. To test this, we collected 840 speech samples along with measures of executive and semantic ability from 60 young and older adults, using a novel computational method to quantify coherence. Semantic selection ability predicted coherence, as did level of semantic knowledge and a measure of domain-general executive ability. These factors fully accounted for the age-related coherence deficit. Our results indicate that maintaining coherence in speech becomes more challenging as people age because they accumulate more knowledge but are less able to effectively regulate how it is activated and used.
Promoting Academic Writing Students’ Skills through “Process Writing” Strategy
Authors: Listyani -
Published: September 2018

Writing in a second language is complex, and complicated, mainly because of by the addition of new resources and norms (new structural elements of the new language, new rhetorical conventions, and some other things). Teachers therefore, whether they like it or not, have to select the most appropriate teaching methods and strategies in their writing classes, one strategy that teachers can apply in their Academic Writing class is Process Writing strategy. This study shows information on a teaching strategy named Process Writing which was applied to one group of Academic Writing class in Semester II, 2016-2017. Research took place from January to April 2016. This group was taught using Process writing teaching strategy, with the hope of helping students improve in both their reading and writing skills. There were 20 students altogether in this group. One central question to be answered in this study is: How effective is Process writing strategy when it is used to teach Academic Writing students? Instruments used were pre-tests, post-tests, direct observation, video-recording; and weekly journals that students had to write every time they passed a stage of the Process Writing. From the statistical analysis as well as from students’ perceptions, one main conclusion can be drawn, that is, Process writing is effective to teach Academic Writing. Another conclusion which is not less significant is that Process Writing can be used to teach any level of education, not to mention in tertiary education, provided that lecturers adjust the materials as well as level of difficulty. One last conclusion is that every strategy that teachers will apply in their classroom is very context-dependent. That is, it depends on the class situation, which varies from one class to another. The context, atmosphere, as well as situation of the class became the factors that contribute to the effectiveness and success of a strategy. This piece of research is hoped to benefit both lecturers as well as students of second language writing. Pedagogically, this research can enrich another source of literature in terms of teacher strategy in teaching second language writing.
Miniaturized Wideband Microstrip Antenna for Recent Wireless Applications
Authors: Shandal S. A. , Mezaal Y. S. , Mosleh M. F. , Kadim M. A.
Published: September 2018

In this paper, a pentagon slot inside fractal circular patch microstrip resonator to design compact antenna over partial ground plane is introduced using 3rd iteration of adopted fractal geometry. This antenna is modeled on FR4 substrate with a size of (20 x 18) mm2, thickness of 1.5mm, permittivity of 4.3 and loss tangent of 0.02. The used type of feeding is microstrip line feed. It is designed to operate at wide frequency range of (4.5-9.3) GHz at resonant frequencies of 5.7GHz and 7.9GHz with impedance bandwidth of 4.8 GHz. Both lengths of ground plane Lg and width of feed line Wf are optimized in order to acquire optimum bandwidth. The simulated return loss values are -33 and -41 dB at two resonant frequencies of 5.7 and 7.9 GHz with gain of 3.2 dB. The simulated results offered noteworthy compatibility with measured results. Also, the proposed wideband microstrip antenna has substantial compactness that can be integrated within numerous wireless devices and systems.
Translational effects of robot-mediated therapy in subacute stroke patients: an experimental evaluation of upper limb motor recovery
Authors: Palermo Eduardo , Hayes Darren Richard , Russo Emanuele Francesco , Calabrò Rocco Salvatore , Pacilli Alessandra , Filoni Serena
Published: September 2018

Robot-mediated therapies enhance the recovery of post-stroke patients with motor deficits. Repetitive and repeatable exercises are essential for rehabilitation following brain damage or other disorders that impact the central nervous system, as plasticity permits to reorganize its neural structure, fostering motor relearning. Despite the fact that so many studies claim the validity of robot-mediated therapy in post-stroke patient rehabilitation, it is still difficult to assess to what extent its adoption improves the efficacy of traditional therapy in daily life, and also because most of the studies involved planar robots. In this paper, we report the effects of a 20-session-rehabilitation project involving the Armeo Power robot, an assistive exoskeleton to perform 3D upper limb movements, in addition to conventional rehabilitation therapy, on 10 subacute stroke survivors. Patients were evaluated through clinical scales and a kinematic assessment of the upper limbs, both pre- and post-treatment. A set of indices based on the patients’ 3D kinematic data, gathered from an optoelectronic system, was calculated. Statistical analysis showed a remarkable difference in most parameters between pre- and post-treatment. Significant correlations between the kinematic parameters and clinical scales were found. Our findings suggest that 3D robot-mediated rehabilitation, in addition to conventional therapy, could represent an effective means for the recovery of upper limb disability. Kinematic assessment may represent a valid tool for objectively evaluating the efficacy of the rehabilitation treatment.
Extent of use of long-acting injectable antipsychotics in children and adolescents within Indiana Medicaid
Authors: Modesitt Taylor , Kubascik Erica , Ott Carol
Published: September 2018

Introduction:

Oral formulations of the antipsychotics aripiprazole, asenapine, lurasidone, olanzapine, paliperidone, quetiapine, and risperidone are indicated for use in pediatrics for several diagnoses. Long-acting injectable (LAI) antipsychotics are of interest in this special population because they may be used due to convenience and desire to improve adherence, despite limited support in the literature. The primary intent of this study is to provide descriptive information on the use of paliperidone palmitate, risperidone microspheres, aripiprazole extended-release injection, and olanzapine pamoate in pediatric patients within Indiana Medicaid.

Methods:

This study was a retrospective database analysis, which retrieved information from Indiana Medicaid over a 2-year timeframe spanning from July 1, 2012, through June 30, 2014. The study included the prescription medications filled for all children and adolescents within Indiana Medicaid who received the LAI antipsychotics paliperidone palmitate, risperidone microspheres, aripiprazole extended-release injection, and olanzapine pamoate.

Results:

From July 1, 2012, through June 30, 2014, 150 Indiana Medicaid patients younger than 18 years old were prescribed a LAI atypical antipsychotic. A total of 1013 LAI atypical antipsychotic doses were billed to Indiana Medicaid during the study period for pediatric patients. Paliperidone palmitate was billed most frequently.

Discussion:

Long-acting injectable atypical antipsychotics are being prescribed for children and adolescents within Indiana Medicaid, despite minimal clinical evidence supporting use. There is a need for further research in this area to increase generalizability of results and aid in implementation of policies to prevent inappropriate use of LAI antipsychotics in children and adolescents.