bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunophenotyping and cytogenetic profile of children with acute lymphoblastic leukemia: A study from a tertiary care center from Kashmir.
Authors: Guru Faisal R , Syed Nisar Ahmad , Bashir Shumail , Vp Sanudev Sadanandan , Ismail Hashim Kunju , Bhat Gull Muhammad
Published: July 2020

Background

The complete cytogenetic and immunophenotyping data in children suffering from acute lymphoblastic leukemia (ALL) in Jammu and Kashmir is scarce. To bridge this knowledge gap the present study proposes to evaluate the immunophenotype and cytogenetic profile of pediatric ALL patients treated in our hospital.

Material and methods

This hospital-based observational study was conducted on 180 pediatric patients aged between 1  to 18 years who had visited the Paediatric unit of the  Department of Medical Oncology at Sher-I -Kashmir Institute of Medical Science, Srinagar ,Jammu and Kashmir between the January 2015 to December 2019.

Result

Among the study participants, 57.8% were male and 42.2% were female with a mean age of 9.24 years and median of 8 Years. Among the participants, 57.2% were below 10 years of age and 42.8% were above 10years of age. CNS disease was reported in 7.8%  of the study participants.  63.3% patients  had a TLC count of less than 20000. Immunophenotyping data revealed pre-B ALL in 77.8% of children. Cytogenetic study was conducted on 153 patients among them 74.4% had a normal karyotype, 7.2% s had hyperdiploidy and 3.3% had hypodiploidy. The FISH analysis showed that 23.3% of study participants were positive for the TEL-AML study, 11.1% were positive for BCR-ABL analysis and 4.4% of participants were positive for MLL gene analysis. The overall survival in the study population was 78.9% among the study participants. Only the MLL gene rearrangement analysis showed a statistically significant correlation with the survival analysis (P<0.5).

Conclusion

In summary, the present study reported the complete cytogenetic and immunophenotyping profile of the children suffering from acute lymphoblastic leukemia in Jammu and Kashmir.
Steroid induced avascular necrosis of femoral head in ALL patients-two case reports
Authors: Guru Faisal , Nisar Syed , Banday Saquib Zaffar , Bhat Gul Mohammad , Shah Saqib Ahmad , Meena Rajendra
Published: July 2020

Avascular necrosis of bone or Osteonecrosis incidence has been increasing in a larger number of surviving ALL patients, especially in adolescents and young adults [1]. Osteonecrosis and decreased bone mineral density(BMD) are well-known side effects of corticosteroids and avascular necrosis has been reported as one of the leading causes of treatment related morbidity in ALL survivors [2]. Symptomatic avascular necrosis has been reported to occur in up to 20% of children and adolescents with ALL [3]. We are reporting two cases of ALL patients who have been treated with steroid and chemotherapy and developed avascular necrosis of bilateral femoral heads.
Testicular Germ Cell Tumour
Authors: Lone Mohammad Iqbal , Lateef Manal Abdul
Published: July 2020

A 23-year-old male presented with chief complaints of painless left testicular swelling for the past 10 days On palpation the patient had a large left scrotal swelling which was firm and non-tender. The results of laboratory evaluation revealed AFP levels of 1212ng/ml which was significantly raised.LDH was 175U/L and bHcg levels were insignificant(1.10U/l)
COVID-19 Disease: a gastroenterologist’s perspective
Authors: Shah Altaf , Dar Hilal Ahmad
Published: July 2020

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has rapidly resulted into pandemic, as first case of coronavirus disease 2019(covid-19) was detected in Wuhan, China in December; 2019.1As of 8 june, 2020, over 7 million infections and more than 402,000 deaths had been reported globally. Although the virus primarily affects the respiratory system and is transmitted via respiratory droplets, various gastrointestinal and hepatic manifestations are not uncommon. Angiotensin-converting enzyme 2 (ACE2), the major receptor of SARS-CoV-2, is expressed in the gastrointestinal tract and liver cells. The detection of SARS-CoV-2 viral RNA in patients’ stool and the potential for faecal–oral transmission has raised great concern and could pose a challenge for the control and prevention of COVID-19 disease.
ENDOSCOPIC MUCOSAL RESECTION
Authors: Shah Altaf , Ahmad Nadeem
Published: July 2020

EMR was developed for minimally invasive, organ-sparing endoscopic removal of benign and early malignant lesions in the GI tract. Endoscopic mucosal resection was pioneered in Japan [Soetikno et al. 2003] for the management of early gastric cancer. This has gained wider acceptance as a therapeutic option for various gastrointestinal lesions around the globe 1.
The vacation season is coming: remember the procedure for calculating them in budget organizations
Authors: Suprotkina Valentina
Published: July 2020

With the onset of the holiday season, accountants will increase their work, because it is they who will have to calculate the vacation pay to employees of their institutions. Article 136 of the Labor Code of the Russian Federation establishes that the payment of vacation pay to a person going on vacation must be made three days before it begins. For violation of the specified time limits to the institution, administrative responsibility measures provided for in art. 5.27 Administrative Code of the Russian Federation. How to timely calculate vacation pay, determine the estimated values when creating a reserve for vacation pay, reect in the accounting of budgetary organizations and prevent mistakes and violations of labor law — we will consider this article.
PENGARUH AKTIVA TETAP DAN AKTIVA LANCAR TERHADAP PENDAPATAN PADA SIMPAN PINJAM PEREMPUAN UPK GERBANG SARI KECAMATAN RENGAT BARAT
Authors: Hapsila Angga
Published: July 2020

This research is about savings and loans for women UPK Gerbang Sari, Rengat Barat District. The research lasted for 5 (five) months. This research try to determine the effect of whether there was a significant influence between fixed assets and current assets on income on women's savings and loans UPK Gerbang Sari, Rengat Barat District. The formulation of the problem to be investigated is whether there is a simultaneous and partial effect between fixed assets and current assets on women's savings and loan income UPK Gerbang Sari, Rengat Barat District. This research used quantitative methods, that illustrates whether there is a significant influence between fixed assets and current assets on income on savings and loans for women UPK Gerbang Sari, Rengat Barat District. To analyzed the data, this research used multiple regression, correlation coefficients, and Hypothesis testing which will be assisted using SPSS version 21. From the results of the study with the regression equation Y = 1,379,231-1,075 X1 + 0,214X2. This means: a = if the fixed assets and current assets are equal to Zero (0), then the value of income is equal to 1,379,231. The coefficient of multiple correlation R is 0.686. and furthermore tested with multiple determination Keofisie (R2 is 0.471. This indicates that (X1) fixed assets and (X2) current assets have together an influence of 47.10% and the remaining 52.90% is influenced by variables other than ( X1) and (X2). Hypothesis testing in which F arithmetic (0.891) <Ftable (3.00), then there is no significant effect simultaneously between fixed assets and current assets to income on savings and loans for women in UPK Gerbang Sari, Rengat Barat District.
STUDI KELAYAKAN INVESTASI PEMBELIAN KAPAL TONGKANG CV. SURYA SAMUDRA SENTOSA
Authors: Fitrio Tomy
Published: July 2020

Tujuan penelitian ini untuk mengetahui kelayakan Finansial Investasi Tongkang baru pada CV. Surya Samudra Sentosa. Adapun alat analisis yang digunakan dalam penelitian ini adalah dengan menggunakan Studi Kelayakan Aspek Keuangan yaitu dengan metode Net Present Value (NPV), Benefit Cost Ratio (B/C), dan Internal Rate of Return (IRR). Kesimpulan hasil dari penelitian ini menunjukan bahwa dari hasil analisis didapatkan NPV sebesar Rp. 2.434.504.000,- yang berarti pembuatan Tongkang baru di CV. Surya Samudra Sentosa layak dijalankan karena NPV menunjukkan angka Positif. Analisis menggunakan Benefit Cost Ratio (B/C), diperoleh nilai Benefit Cost Ratio (B/C) sebesar 1,39 > 1, artinya pembuatan Tongkang baru di CV. Surya Samudra Sentosa layak dijalankan. Dengan menggunakan metode Internal Rate of Return (IRR) didapatkan hasil sebesar 25,86% yang berarti lebih besar dari tingkat suku bunga saat ini yaitu 17 % pertahun, maka pembuatan Tongkang di CV. Surya Samudra Sentosa layak dilaksanakan.
PENGARUH SIMPANAN, PEMBIAYAAN DAN MODAL TERHADAP LABA PADA BTM WAHANA MENTARI KABUPATEN INDRAGIRI HULU
Authors: Hapsila Angga
Published: July 2020

The research was conducted by the writer on BTM Mentari in sub districts rengat - indragiri upstream. District. The research phase lasting three months. This research study is to find savings, influence financing and capital to profit in the district btm mentari Indragiri upstream.

This research used secondary data , writer process data by using multiple linear regression the it using spss ( statistic package for social scince ) 24 version to get output to summarizing the research.

The research that is simultaneously a conclusion can be drawn is the significant savings, between financing and capital to profit. This can be seen that the f count greater than the f table ( 29,873 > 2,36 ) When viewed from the table a model summary so r which means a correlation coefficient obtained value of 0,984 which means the amount of savings mobilized , the financing of the and capital had strong ties against spider does not permit the .Was in the middle of the value of the coefficients detrminasi as much as 0,968 paper work showing that the amount of savings mobilized , the financing of the and capital affect of the spider that has been accepted by the BTM the spacecraft mentari as much as 96,80 % the remaining of 3,20 % influenced by the fact that of other variables that do not writer you wherever you may be.
PENGARUH PERSAINGAN DAN PROMOSI TERHADAP PENDAPATAN PADA FOTOCOPY ANUGRAH RENGAT
Authors: Warnadi Warnadi
Published: July 2020

Penelitian ini dilakukan terhadap Fotocopy Anugrah Rengat dengan tujuan untuk mengetahui pengaruh variabel Persaingan dan promosi terhadap Pendapatan pada Fotocopy Anugrah Rengat.

Pengambilan sampel dilakukan dengan metode accidental random sampling dengan 91 orang sampel sebagai responden. Metode analisis yang digunakan adalah metode deskriptif kuantitatif, analisis data dilakukan secara parsial dan simultan (analisis regresi linear berganda dengan bantuan program IBM SPSS Stastic versi 21.0).

Dari hasil penelitian, diperoleh persamaan regresi yaitu Y = 11,496 - 0,354X1 + 0,961X2, terlihat bahwa Persaingan dan Promosi memiliki pengaruh yang positif terhadap Pendapatan pada Fotocopy Anugrah Rengat. Selain itu, pengujian secara simultan (Uji F), telah diperoleh F hitung > F tabel yaitu sebesar 50,596 > 3,10. Sehingga kedua variabel bebas yaitu Persaingan dan promosi secara bersama-sama berpengaruh positif dan signifikan terhadap variabel terikat yaitu Pendapatan pada Fotocopy Anugrah Rengat. Sedangkan Uji Regresi Parsial (Uji t) menunjukkan bahwa variabel promosi lebih dominan berpengaruh signifikan terhadap Pendapatan pada Fotocopy Anugrah Rengat yaitu t hitung > t tabel sebesar 9,840 > 1,98698. Demikian variabel Persaingan berpengaruh signifikan terhadap Pendapatan pada Fotocopy Anugrah Rengat yaitu t hitung > t tabel sebesar -3,110 < -1,98698. Selain itu, Hasil dari koefisien korelasi berganda adalah sebesar 0,731 yang menunjukkan tingkat hubungan antara seluruh variabel independent terhadap variabel dependent dalam penelitian ini berada dalam kriteria keeratan hubungan kuat. Besarnya pengaruh yang ditimbulkan oleh kedua variabel ini secara bersama-sama mempengaruhi variabel Pendapatan dengan persentase 53,5%, Sedangkan 46,5% dipengaruhi oleh faktor lain yang tidak ikut dalam penelitian ini.
SWOT ANALYSIS ON IKM KUE BAWANG BINA KARYA OF INDRAGIRI HULU REGENCY
Authors: Putri Meilya Karya , Corrina Fatti
Published: July 2020

his research aimed to analyze the external and internal environment in IKM Kue Bawang Bina Karya of Indragiri Hulu Regency by using SWOT Analysis. This research was conducted in December 2019.

This research used mixed method, a combination between descriptive-qualitative and quantitative methods. The data used were primary and secondary data which were collected through interviews, observation, documentation and questionnaires. The subject and data sources of this research were the Consumers of IKM Kue Bawang Bina Karya of Indragiri Hulu Regency, the Owner of IKM Kue Bawang Bina Karya of Indragiri Hulu Regency, and The Industry and Trade Agency of Indragiri Hulu Regency.

The results of this research showed that, currently, IKM Kue Bawang Bina Karya supported aggressive strategies that are applicable, namely Market Development Strategy, Market Penetration Strategy, Product Development Strategy, Forward Integration Strategy, Backward Integration Strategy, Horizontal Integration Strategy, and Diversification Strategy.
THE INFLUENCE OF MANAGEMENT INFORMATION SYSTEM (SIM) TOWARD APARATUR PERFORMANCE AND INSTITUTIONAL INSTITUTIONS OF KUALA VILLAGE, KILAN SUB-DISTRICT, BATANG CENAKU DISTRICT, INDRAGIRI HULU DISTRICTS
Authors: Hairudin Abdul , Sholihat Walmi
Published: July 2020

This research was conducted in the village of Kuala Kilan, Batang Cenaku District - Indragiri Hulu Regency. The type of data used in this study is primary data obtained from the recapitulation of questionnaires from the Village Apparatus and Community Institutions of Kuala Kilan Village. The analysis that I use is Simple Regression Analysis using SPSS (statistical package for social sciences) version 21 to get the output to conclude the results of this study. The results of the study concluded that the Management Information System (SIM) affected the Performance of Apparatus and Social Institutions in Kuala Kilan Village, Batang Cenaku Subdistrict, Indragiri Hulu Regency, it can be seen that the calculated t value was greater than t table (4,875> 2,03951). Based on data testing criteria, it can be seen that H0 is rejected and Ha is accepted, meaning that the Management Information System (SIM) partially influences the Performance of Apparatus and Community Institutions.
IMPLEMENTATION OF VILLAGE HEAD SELECTION USING ELECTRONIC VOTING (E-VOTING) METHODS IN INDRAGIRI HULU DISTRICT
Authors: Yusnedi Yusnedi , Utami Sabrina , Heriasman Heriasman
Published: July 2020

This research was conducted in Indragiri Hulu district, where this research used three villages that held head selection by using electronic voting, there are: Sidomulyo, Sungai Baung and Batu Gajah. This research used qualitative descriptive approach with the consideration that the researcher intends to obtain a picture of the Community Readiness for the Implementation of Village Head Election using the Electronic Voting (E-Voting) method in Indragiri Hulu District. This research used observation, interviews and documentation to collected all the data.

The results of this study indicate that the application of the use of electronic voting in the three villages is already good, where this is indicated by the majority of the community that can already use the e-voting tool. only a small portion of the community still does not understand how to use it.
THE EFFECT OF CHARACTER, CAPACITY, CAPITAL, COLLATERAL AND CONDITION OF ECONOMY ON GIVING CREDIT
Authors: Hapsila Angga , Astarina Ivalaina
Published: July 2020

This research was conducted by the authors at PT Bank Rakyat Indonesia (Persero) Tbk Kerumutan Unit and Tri Mulia Jaya Unit. The research took place for 4 ( four ) months. Conducting this research is to determine the effect of Character, Capacity, Capital, Collateral, and Condition of Economy simultaneously on the Provision of Credit at PT. Bank Rakyat Indonesia (Persero) Tbk Kerumutan Unit and Tri Mulia Jaya Unit.

This study uses primary data, the authors conducted data processing using multiple linear regression which processed it using SPSS (statistical package for social science) version 21 to get the output to conclude the results of this study.

From the results of the study, it can be concluded that simultaneously there is a significant influence between Character, Capacity, Capital, Collateral, and Condition of Economy on the Provision of Credit. When viewed from the summary model table, then r, which means the correlation coefficient, shows that Character, Capacity, Capital, Collateral, and Condition of Economy have a moderate relationship to the Provision of Credit.
ДОСЛІДЖЕННЯ РЕЖИМІВ РОБОТИ ПІЛОТНОЇ ЕЛЕКТРОТЕРМІЧНОЇ ПЕЧІ КИПЛЯЧОГО ШАРУ ПРОДУКТИВНІСТЮ 10 КГ/ГОД
Authors: Fedorov Serhii , Sybir Artem , Hubynskyi Mykhailo , Hubynskyi Semen , Foris Svitlana , Gogotsi Alexey , Koval Serhii
Published: July 2020

Мета. Метою дослідження режимів лабораторної електротермічної печі киплячого шару продуктивністю 10 кг/год було отримання нових науково-практичних даних про вольт-амперні характеристики подібних агрегатів для подальшого вибору відповідних електричних джерел живлення.Методика. Дослідження роботи печі виконувалось шляхом математичного моделювання її теплового балансу та електричного опору у відповідних режимах. Для побудови вольт-амперних характеристик були використані залежності для електричної потужності та питомого електричного опору шару, а також рівняння загальної, корисної потужності і потужності холостого ходу за різних значень робочої температури і продуктивності.Результати. Побудовані і досліджені воль-амперні характеристики печі киплячого шару продуктивністю 10 кг/год, які включають: характеристики електротермічного киплячого шару для певних значень температури в діапазоні від 0 до 2700 °С; характеристики електротермічного киплячого шару для продуктивності печі G = 0 – 10 кг/год; криві щільності струму на поверхні центрального електроду, на поверхні футеровки і середньої за радіусом печі i(I); криві постійної потужності N = const в діапазоні 5 – 40 кВт. На основі аналізу результатів визначена область сталої роботи електротермічної печі, яка виключає ймовірність короткого замикання. Розроблені режими розігріву, зміни температури і продуктивності, а також алгоритми забезпечення заданих продуктивності й температури.Наукова новизна. Вперше науково обґрунтовано вибір режимів управління електричною потужністю електротермічної печі киплячого шару на основі її вольт-амперних характеристик та визначено область сталої роботи.Практична значущість. За результатами досліджень визначені вимоги та відповідно розроблене технічне завдання на виготовлення електричного джерела живлення лабораторної електротермічної печі киплячого шару продуктивністю 10 кг/год для умов ТОВ "Центр Матеріалознавства" (Київ, Україна).
ПРОТИКОРОЗІЙНІ ВЛАСТИВОСТІ НАНОРОЗМІРНИХ ПЛІВОК, УТВОРЮВАНИХ ЛЕТКИМИ ОРГАНІЧНИМИ СПОЛУКАМИ РОСЛИННОГО ПОХОДЖЕННЯ
Authors: Vorobyova Victoria , Chyhyrynets Olena
Published: July 2020

Мета. Розробка екологічно безпечного леткого інгібітора для захисту від атмосферної корозії вуглецевої сталі на основі рослинних відходів, а саме вичавок промислової переробки абрикоса. Методика. Протикорозійну ефективність летких фракцій інгібітора оцінено методами прискорених корозійних випробувань. Морфологію та товщину утворених плівок вивчено за допомогою скануючої атомно-силової мікроскопії. Результати. Встановлено, що високо захисна плівка летких органічних сполук вичавок абрикоса товщиною до 250 нм формується не менше, ніж 48 годин, забезпечуючи гальмування анодної і катодної реакцій корозії в умовах періодичної конденсації вологи. В оптимальній концентрації летких сполук забезпечується повний захист металу від корозії. Наукова новизна. Показано, що вичавки промислової переробки абрикоса є сировиною для  створення ефективного екологічно безпечного інгібітору для тимчасового захисту металопрокату від атмосферної корозії. Визначено особливості процесу формування захисної плівки та її товщину. Практична значимість. Результати свідчать про ефективність використання пакувальних матеріалів з вітчизняними леткими інгібіторами на основі рослинних відходів (вичавок абрикосу) для використання виробниками металопрокату з метою підвищення конкурентоспроможності металопродукції.
How to Deal with the Increasing Risk of Sino-US Cold War
Authors: Lixing Zou
Published: July 2020

With the increasingly complicated, sensitive and perilous Sino-US relations amid the COVID-19 pandemic, it requires a historical, comprehensive and systematic thinking to deal with the increasing risk of Sino-US cold war. This paper conducted some preliminary and systematic analysis into the crux and the approaches to resolve the tensions. At such a critical juncture of the Sino-US relations, the crux of problems is manifested in the following aspects: coronavirus-related stigma; all-round trade disputes; politicization of trade; complication of politics; directly targeted strategy; deteriorating corporate and social base; ideological radicalization. The principal contradictions are those incurred by different national strategic interests. The US is worried about being replaced by China and the impact of China’s “nationwide system” on the current international system. On the other hand, China is worried about the US’ interference into its internal affairs, system building and national reunification, as well as the US’ efforts to contain China’s development.
Results of Salt Cognition Test using SALSAVE since 67 Female University Students
Authors: Katayama Naomi , Ito Akemi , Hirabayashi Mayumi
Published: July 2020

In Japan, salt reduction is encouraged to prevent high blood pressure. However, it is difficult to reduce salt, and good salt intake per day did not fail to the target value. In this study, we report a saltiness cognitive threshold test using female university students. The participant is 67 female university students. Participants were subjected to a salty cognitive threshold test using SALSAVE (manufactured by Advantech). The saltiness test started from a light taste and tried a strong taste in order. The salt concentration is 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, 1.6%. We also conducted a questionnaire survey on eating habits. As a result, 62 out of 67 female university students who felt salty at a concentration of 0.6% were 92% of all participants. However, two female university students did not feel taste even with a salt concentration of 1.6%.They are 3% of all participants. As a result of the questionnaire survey, female university students answered that they had a good taste and secreted saliva well, and they usually had a rather light diet. In the future, we would like to increase the number of participants and compare more detailed dietary habits with SALSAVE results.
Result of the Threshold Test for Saltiness Perception of 35 People who Participated in the Saltiness Test using Test-Disk at the University Festival
Authors: Katayama Naomi , Hirabayashi Mayumi , Ito Akemi
Published: July 2020

Hypertension is one of the causes of many lifestyle-related diseases. In Japan, too, we are raising awareness about dietary salt reduction for hypertensive patients. Therefore, the purpose of this study was to understand the results of the salty cognitive threshold test in a wide range of age. This result can be useful data for future salt reduction instruction. Thirty-five people participated in the saltiness cognition threshold test at the university festival. The participants this time had a wide range of ages from the teens to the eighties. Participants answered that they eat out 2-3 times a week. Also, they said that the seasoning they like to eat is a little salty. Most participants (88.6%) perceived saltiness below 1.25%. Four participants (one male and three females) recognized saltiness in 5.0%. There was no participant didn’t recognize the saltiness of all. In the future, it will be better to conduct a questionnaire survey on dietary habits and compare it with the saltiness cognitive threshold test results.
Causes and Preventions of Coronavirus (COVID-19)
Authors: Kim Tai-Jin
Published: July 2020

Parameter is causing the coronavirus (COVID-19) pandemic was CO2 emissions, correlated with total cases (R2=0.8064) and deaths (R2=0.7627). CO2 emissions produced by coal and gas-powered plants, oil refineries, vehicle, metropolitan food waste gas, human exhalation, leather-tannery industry, and organic dye industry. Cetaceans, including whales, dolphins, and porpoises, transmitted the globe with the coronavirus. The sudden spread of the coronavirus could cause by the 14 habitats of humpback whales, linked to millions of dolphins as well as the global leather tanning industry. It is necessary to monitor the sunspot number to prepare for the effects of cyclic minimum sunspot number in 2031. Because the top 2 countries of CO2 emissions are China and the USA, a new pandemic in 2031 may initiate either from China or from the USA, as H1N1 (the USA, 2009) or as COVID-19 (China, 2020). The preventive phenomena of the third pandemic in 2031 can be monitored at humpback whale districts, as happened in 130 dead dolphins in Cape Verde, at least three months earlier before COVID-19 in China. UV-B radiation is the most efficient method to kill the virus itself.
Disruptive Gravity: A Quantizable Alternative to General Relativity
Authors: Safo Ramsès Bounkeu
Published: July 2020

Gravity is the most problematic interaction of modern science. Questioning the very foundations of gravity might be the key to understanding it better since its description changed over time. Newton described it as a force, Einstein described it as a spacetime curvature and this paper shows how gravity can be described as a force able to bend spacetime instead. Applied to cosmology, gravity as a spacetime bending force doesn't require Dark Energy. Described as a spacetime bending force, gravity becomes quantizable as a force in curved spacetime which is compatible with the Standard Model of particle physics. Therefore, one could associate the Standard Model to this theory and achieve Quantum Gravity.
DETERMINAN KEJADIAN KANKER PAYUDARA DI RSUD 45 KUNINGAN PERIODE TAHUN 2018-2019
Authors: Soviyati Evi , Gani Utari Toto Sutarto , Nabila Putri
Published: July 2020

Kanker payudara merupakan ancaman bagi kaum wanita, dan merupakan peringkat kedua penyebab kematian perempuan. Laporan Rumah Sakit Dharmais, 70% wanita yang datang sudah dengan stadium lanjut, sisanya 30% terdiagnosis pada stadium I atau II (pasien dalam usia 25-80 tahun). Tujuan penelitian adalah mengetahui determinan kejadian kanker payudara di Instalasi Rawat Inap Rumah Sakit Umum Daerah 45 Kuningan Periode Tahun 2018-2019. Jenis penelitian yang survey analitik dengan pendekatan survey case control, menggunakan data sekunder dengan jumlah total sampel 30 orang. Analisis data menggunakan Chi-Squrae. Hasil penelitian menunjukan bahwa dari ketiga faktor yang diteliti, terdapat dua faktor yang berhubungan dengan kasus kanker payudara, yaitu faktor umur dengan p value 0,001 dan pendidikan dengan p value 0,034. Sedangkan faktor riwayat keluarga dinilai tidak berhubungan karena memiliki p value 0,767. Diharapkan lebih meningkatkan akses sumber informasi bagi para pendidik dan atau bidan. Hal ni bertujuan agar adanya perhatian yang lebih terhadap masalah kanker payudara sebagai salah satu penyebab faktor risiko kematian kanker tertinggi kedua pada wanita. Sehingga bisa direncanakan strategi-strategi untuk menurunkan angka kejadian kanker payudara dan komplikasi dari keadaan tersebut.
PENGALAMAN ORANG TUA DALAM MERAWAT ANAK PENDERITA KANKER DI RUMAH HARAPAN YAYASAN VALENCIA JAKARTA
Authors: Pusmaika Rangga , Indrayani Indrayani , Agustin Dewi , Demang Fransisca Yuniati
Published: July 2020

Kanker merupakan penyakit kronis penyebab penting kematian pada anak. Penyakit kronis yang diderita anak dalam hal ini kanker, dapat memberikan respon yang berbeda-beda pada keluarga. Penelitian ini bertujuan untuk diperolehnya informasi yang mendalam tentang pengalaman orang tua dalam merawat anak penderita kanker di Rumah Harapan Yayasan Valencia Jakarta. Metode yang  digunakan adalah kualitatif,  dengan  Rapid Assessment Procedures (RAP).  Pnelitian dilakukan pada Mei 2016. Populasi  penelitian  seluruh  orang  tua  yang  memiliki  anak  penderita kanker di Rumah Harapan. Pengambilan sampel  dalam  penelitian  ini adalah menggunakan  metode purposive sampling. Hasil penelitian menunjukan selama merawat anak yang menderita kanker, orang tua mengalami stress, diperlukannya perawatan khusus bagi pasien kanker, Diperlukan adanya dukungan dalam bentuk psikososial, material dan sosial terhadap orang tua, kondisi kesehatan anak menurun merupakan hambatan terbesar bagi orang tua, diperlukan kebutuhan material dalam mendukung keperawatan, spiritual dan psikososial bagi orang tua dalam merawat anak yang menderita kanker, serta adanya harapan orang tua agar anaknya segera sembuh.
PERBANDINGAN KADAR HEMOGLOBIN PADA REMAJA PREMENARCHE DAN POSTMENARCHE DI DESA RAGAWACANA KECAMATAN KRAMATMULYA KABUPATEN KUNINGAN TAHUN 2018
Authors: Herwandar Fera Riswidautami , Soviyati Evi
Published: July 2020

Anemia merupakan salah satu masalah kesehatan di seluruh dunia terutama negara berkembang. Anemia pada remaja putri sampai saat ini masih cukup tinggi. Di Indonesia terdapat 21,7% penduduk dengan kadar hemoglobin kurang dari batas normal. Remaja putri memiliki risiko sepuluh kali lebih besar untuk menderita anemia dibandingkan dengan remaja putra. Hal ini dikarenakan remaja putri mengalami mentruasi setiap bulannya. Tujuan penelitian ini adalah untuk mengetahui perbandingan kadar hemoglobin pada remaja premenarche dan postmenarche.Metode yang digunakan dalam penelitian ini adalah analitik dengan rancangan case control. Teknik pengambilan sampel yaitu dengan purposive sampling. Teknik pengumpulan data menggunakan lembar observasi dan pemeriksaan hemoglobin dengan menggunakan hemoglobin meter. Uji hipotesis menggunakan uji t test independent.Hasil penelitian dari 42 responden yang telah diobservasi didapat rata-rata kadar hemoglobin pada remaja premenarche adalah 12,9 gr/dl. Sedangakan pada remaja postmenarche adalah 12,0 gr/dl. Hasil analitik didapatkan tidak terdapat perbedaan pada kadar hemoglobin premenarche dan postmenarche dengan nilai p value 0,087.Berdasarkan hasil penelitian, penulis dapat menyimpulkan bahwa menstruasi dapat memengaruhi terhadap penurunan kadar hemoglobin secara signifikan.Bagi Desa Ragawacana Kecamatan Kramatmulya Kabupaten Kuningan diharapkan dapat bekerja sama dengan Puskesmas atau tenaga kesehatan lainnya, untuk memberikan pendidikan kesehatan tentang gizi seimbang remaja, kesehatan reproduksi, serta dapat mendukung program pemerintah yang sudah ada yaitu pemberian asam folat dan tablet tambah darah.
PENGARUH KADAR KORTISOL TERHADAP KECEMASAN IBU BERSALIN DALAM PENGATURAN LINGKUNGAN PERSALINAN
Authors: Lestari Lusi , Heryani Heni
Published: July 2020

Kecemasan ibu bersalin yang terjadi terus menerus dapat memengaruhi sistem saraf simpatik dan pelepasan hormon penyebab stres. Hormon yang produksinya meningkat karena persalinan diantaranya adalah hormon kortisol. Kortisol mempunyai banyak peran dalam sistem metabolisme dalam tubuh. Pengalaman persalinan dipengaruhi oleh lingkungan dan tempat berlangsungnya persalinan. Lingkungan dapat memberikan efek yang besar terhadap terjadinya kecemasan ibu bersalin. Memperhatikan aspek lingkungan ruang persalinan termasuk pendekatan non farmakologis untuk mengatasi kecemasan. Penelitian ini bertujuan untuk mengetahui pengaruh hormon kortisol terhadap kecemasan ibu bersalin dalam pengaturan lingkungan persalinan. Penelitian ini menggunakan metode eksperimen semu pre post test with control group design dengan 60 ibu bersalin di Bidan Praktik Mandiri (BPM). Uji analisis statistiknya menggunakan Uji Mann-Whitney, Uji T Tidak Berpasangan dan Uji Regresi Ganda. Hasil penelitian menunjukan terdapat perbedaan rerata skor kortisol post (p = 0,000) dan peningkatan kortisol (%) (p = 0,007) pada kelompok perlakuan dan kelompok kontrol. Terdapat perbedaan rerata skor kecemasan saat pengukuran kedua pada kelompok perlakuan dan kelompok kontrol (p = 0,007). Peningkatan kadar kortisol (%) tidak memiliki kolerasi yang bermakna dengan kecemasan ibu bersalin karena nilai p ≥ 0,05. Simpulan penelitian ini adalah tidak ada pengaruh kortisol terhadap kecemasan ibu bersalin dalam pengaturan lingkungan persalinan.
Konsepsi Pendidikan Anti Korupsi Dalam Persepektif Al-Qur’an
Authors: Sulaiman Sulaiman
Published: July 2020

Masyarakat dan ketertiban merupakan dua hal yang berhubungan sangat erat, bahkan bisa juga dikatakan sebagai dua sisi dari satu mata uang.Susah untuk mengatakan, adanya masyarakat tanpa ada suatu ketertiban.Ketertiban dalam masyarakat diciptakan bersama-sama oleh berbagai lembaga, seperti hukum dan tradisi. Oleh karena itu, dimasyarakat akan dijumpai berbagai macam pedoman, patokan atau ukuran yang masing-masing memberikan kontribusinya dalam menciptakan ketertiban. Pedoman, patokan, atau ukuran  untuk berperilaku atau bersikap dalam kehidupan bersama disebut norma atau kaidah sosial. Diantaranya adalah normahukum.

Hukum menetapkan apa yang harus dilakukan dan atau apa yang boleh dilakukan serta yang dilarang. Sasaran Hukum yang hendak dituju bukan saja orang-orang yang nyata-nyata berbuat melawan hukum, melainkan juga perbuatan hukum yang mungkin akan terjadi, dan kepada alatperlengkapan negara untuk bertindak menurut hukum.
SYNERGY OF LEAN TECHNOLOGIES AND DIGITALIZATION IN THE CONTEXT OF INCREASING THE EFFECTIVENESS OF PROCESSES IN AN EDUCATIONAL INSTITUTION
Authors: Vermennikova L.V. , Lupishko A.N. , Veselova D.V.
Published: July 2020

Digitalization of universities is an actual trend of our time, due to the direction of development of the Russian economy, focused on improving its efficiency. The tools for achieving this goal are largely lean and digital technologies.The existing regulatory framework of the Russian Federation in the field of effective development is analyzed. The object of analysis is federal and national projects and programs, the purpose of which is to increase labor productivity, ensure the quality and accessibility of services in various fields. The existence of links between federal projects aimed at improving the efficiency of various sectors of the economy through the introduction of lean manufacturing and projects aimed at creating a digital space is demonstrated. The necessity of conforming the development path of educational structures to the vectors of modern social development is substantiated in terms of transferring their internal processes to a qualitatively new level using lean technologies and digitalization of processes. The experience of implementing projects for improvements using lean technologies and digitalization at the Kuban State Medical University is described. The analysis of the effectiveness of projects implemented in the framework of the concept of "Lean university", with the use of digitalization and without its use. Conclusions are drawn about the limitations of the use of digitalization to improve the efficiency of processes, the risks of its use in educational institutions, as well as the need for the synthesis of lean technologies and digitalization in the context of the effective development of organizations.
REASONS AND FEATURES OF IMPLEMENTING BLOCKCHAIN TECHNOLOGY IN THE PENSION SYSTEM OF THE RUSSIAN FEDERATION
Authors: Volkova T.G.
Published: July 2020

Due to the introduction of the digital economy on the territory of the Russian Federation and the urgency of the problem of implementing the distributed registry system (Blockchain) in various financial spheres, including the system of accounting for pension rights and obligations in the state and non-state pension systems, an attempt was made to assess the principles of implementing the Blockchain mechanism in the system of accounting for pension rights, insurance premiums and pension payments. The current system of centralized registries is based on the full confidence of its participants-clients. In particular, persons insured in the pension system. The non-transparency of the non-state pension component and the periodic changes in the state pension system seriously undermine this trust of citizens. Thus, the system of distributed registries that will solve this problem operates on the principles of transparency, availability for verification, reliability (security of transactions), economy, and trust on the part of customers. The article also considers the problem of formation and distribution of the accumulative pension component. The analysis of its losses and features of transfer to different pension organizations - participants of the state pension insurance system is carried out. It is proposed to solve the problems associated with these processes by implementing a system of distributed registries and smart contracts. In conclusion, the advantages and disadvantages of the distributed registry system are presented, as well as the difficulties of its implementation in the near future in the pension system of the Russian Federation are analyzed.
TODAY's SMART CITY TRENDS IN THE WORLD
Authors: Katochkov V.M. , Savin G.V. , Toporkova E.V.
Published: July 2020

Digitalization today is a modern trend focused on streamlining processes and improving efficiency. The introduction of information and communication technologies has affected not only enterprises, but complex socio-economic systems as cities, and this predetermined the development of smart cities. Today, IBM, McKinsey or Price Waterhouse are considered the brain centers for the development of this concept, while Siemens, BMW, Mercedes Benz, IBM, Phillips, General Electric, etc., discovered the “smart” city as a future-oriented concept, and chose only that a niche in which they can offer their products and services. The development of smart cities is also influenced by intergovernmental organizations and their specialized departments, as well as research centers, institutes and laboratories. There are more than 100 cities in the world that claim the title of “smart city”. At the same time, their current ratings reflect the implementation of modern information and communication technologies in the life of a person with the aim of improving the quality of his life in the development of the urban environment. The IESE Cities in Motion Index, Global Power City Index, The Global Cities Index, The Global Cities Outlook, Juniper Research, EasyPark Smart City Index ratings provide sufficient and comprehensive indicators to give this title. The developed standards ISO 37120 and ISO 37122 determine the main indicators for smart cities, while the criteria that determine the achievement of city smartness are conditionally formed today, which allows to clarify the semantic loads implemented in this definition, namely, to prioritize technologies for people and society, improving quality of life, and highlight differences with other similar definitions.
ACTUAL PROBLEMS IN ASSESSMENT OF THE REGIONS' INVESTMENT POTENTIAL
Authors: Rezepin A.S. , Mikhailov M.A.
Published: July 2020

The analysis of existing methods for assessing the investment potential of Russian regions has shown that there are a number of problems with an objective assessment of the investment development of regions. The using of the regions’ investment potential assessing methods without taking into account the factors of municipalities’ investment development raises doubts about the results’ objectivity. In this work the authors set a goal to assess the influence of individual factors on the Russian regions’ investment potential by calculating the index of municipal districts’ investment opportunities, which allows to identify problems with investment development of the region. The research is based on economic-mathematical modeling by the Russian subjects’ official statistics information with the Cherepovets municipal district of the Vologda region as example. The research allowed us to determine the impact of investment processes in municipal areas on the Russian region’s investment potential. In particular, to determine that the process of investment development in municipal areas depends on several fundamental factors: in most areas there is intraregional labor migration, which affects the objectivity of the municipal areas labor potential’s assessment. Thus, the proposed method of evaluating the investment opportunities index of municipal districts is an effective tool for analyzing the development of Russian regions’ investment potential, it can be used as a management tool, and also allows us to identify problem areas in the investment processes of region. The results of the research can be used in analyzing and monitoring the Russian Federation subject’s investment potential, determining the needs for further investment development of individual municipal districts of the region.
INVESTMENT IN HUMAN CAPITAL IN THE CONDITIONS OF INNOVATIVE ECONOMIC DEVELOPMENT
Authors: Tikhonova E.N. , Korepanova I.V.
Published: July 2020

Paradoxically, economic slowdown has been one of the major current trends alongside with intensive technology development. Changes in nature of production require employees to acquire qualitatively different skills that were not were not previously needed. In particular, one of them is being able to provide diffusion of innovations. Consequently, investment in human capital is gaining a new meaning, the quality of which contributes to long-term economic growth in modern socioeconomic reality. Investing is being implemented on different levels, starting from an individual and all the way to a company or a government. Every entity plays their own special role in the process of achieving the common goal of improving the quality of human capital. Investing in entities from different levels requires different tools, mechanisms and involves different kinds of risks for investors. Benefits gained from human capital don’t only belong to investors but also take the form of positive externalities.
THE TERRITORIAL SCHEME OF WASTE MANAGEMENT AS A REGULATORY INSTRUMENT FOR THE FORMATION OF A SEPARATE WASTE COLLECTION SYSTEM
Authors: Druzhakina O.P.
Published: July 2020

The issues of application of the Territorial scheme of waste management in the Udmurt Republic and legal regulation in the field of municipal waste management from the position of forming a system of separate waste collection are considered. The main focus is on the regulatory and management mechanism for the application of the Territorial scheme from the point of view of the formation of waste processing infrastructure, their use as secondary raw materials and the introduction of waste separation collection. The article analyzes the experience of various countries in minimizing the anthropogenic impact of waste and introducing separate collection with the extraction of secondary raw materials using legal methods. There are "gaps" in the practice of developing and implementing a Territorial scheme as a resource for creating an administrative and legal field for separate waste collection and from the point of view of attracting the processor, as well as from the point of view of forming the ecological culture of the population. Conclusions are drawn and recommendations are made on the need to include in the points and sections of the scheme, on the example of the Udmurt Republic, mechanisms for implementing separate waste collection, forming an environmental culture of the population and attracting processors as active participants in the MSW management system.
SOME QUESTIONS OF CRIMINAL LEGAL RESPONSIBILITY IN THE FIELD OF APPLICATION OF ARTIFICIAL INTELLIGENCE SYSTEMS AND ROBOTICS
Authors: Kamalova G.G.
Published: July 2020

The article discusses the problems of improving criminal law in the context of the development of one of the types of breakthrough digital technologies - artificial intelligence. The author notes that the explosive development in this area has led to the growth of high-tech crime, a special place among which is occupied by crimes using tools of artificial intelligence technology. Since the subjects of criminal activity traditionally use advanced technologies, at present such crimes are already represented by fraud, computer information crimes, terrorism, violations in the field of road safety, violation of the right to privacy and a number of others. Although there are no special offenses related to artificial intelligence in the criminal law today, this does not mean that existing norms cannot be applied to traditional subjects. Given the current level of development of artificial intelligence technology, it is now necessary to strengthen criminal liability for the compositions provided for by the current Criminal Code of the Russian Federation by introducing an appropriate qualifying attribute. With the recognition of the legal personality of artificial intelligence systems and robots, one of the key issues of applying criminal law rules to them will be the question of the subjective side of the committed act. The lack of “strong” artificial intelligence and the current level of development of solutions and devices based on artificial technology allow us to limit ourselves to classifying the facts of their use as components of the objective side of the crime.
ABOUT SOME PROBLEM ASPECTS OF LEGAL CATEGORY OF PARTIAL INSANITY
Authors: Kolmakov P.A.
Published: July 2020

The article studies some problem issues rising with formation of criminal category of partial insanity in home legislation. Legislative attaching of this legal category at article 22 of Russian criminal code had passed along path of discussions and heated arguments that still in place. The study makes a primary accent at legal assessment of mental anomaly criminal personality and his responsibility realization mechanism in law enforcement activities. It is noted that when the identical crime is committed the extent of guilt and responsibility of such subjects could be different depending on intention matter, mental integrity and various external conditions. Personality of such criminal could be more dangerous than personality of healthy one because he has to control his behavior mechanisms more thoroughly. The article gives empirical data from different sources and reputable scientists’ opinions to prove author position. The article makes a conclusion that final mental anomaly criminal personality assessment differs from legislative position of Western European countries. Non-coordinations and gaps of such kind of criminal cases sentence realization that need further serious examination and adjustments remains in domestic legislation.
GAPS IN THE LAW AND WAYS TO FILL THEM
Authors: Lushnikov P.V.
Published: July 2020

The article deals with the issues of gaps in law, it is stated that at present the problem of gaps is caused by the development of public relations. The negative consequences of gaps and their causes are determined. Several classifications of gaps that are made in science are considered. It is concluded that the deliberate creation of gaps by the subjects of law-making can be a corruption-induced factor. The classification of gaps depending on the truth (real and imaginary) is analyzed in detail. It is concluded that under the imaginary spaces can occur, both the addressees and the addressees of legal messages. In the first case, the addressees due to lack of necessary knowledge may have a false idea about the lack of legal regulation. When considering the second option, there is agreement with the scientific position that the addressees may, for subjective reasons, try to resolve gaps in the law, which do not really exist, thereby giving rise to excessive legitimization or real gaps. The article considers the options of filling the gaps in the law proposed in science. Further, it is proposed to apply to this problem the provisions of hermeneutics. The possibility of applying hermeneutic methodology to eliminate gaps is substantiated. It is concluded that preliminary modeling of communicative processes in the course of law-making can be used as a measure to counteract the gap in laws. The author suggests the need to limit the "arbitrariness of the reader" in the process of applying the analogy of law and law, as well as in the process of forming a legal precedent.