bluuebunny/crossref_metadata_2025 huggingface dataset:
STRUCTURE OF MICROORGANISMS ISOLATED FROM BRONHOALVEOLAR LAVAGE FROM PATIENTS IN THE DEPARTMENT OF REANIMATION AND INTENSIVE THERAPY
Authors: Medvedeva E. D. , Kezko Yu. L. , Ismatullin Danir Damirovich , Lyamin A. V. , Kondratenko O. V. , Zhestkov A. V.
Published: July 2020

The aim of the work was to determine and compare the structure of microorganisms isolated from bronchoalveolar lavage from patients in the ICU of Clinics in 2016 and 2019. This work presents the results of a bacteriological examination of 229 samples from 139 patients for 2016 and 387 samples from 218 patients for 2019. The predominant microorganism in 2016 was Acinetobacter baumanii - 75 (26.2%). Less common were Klebsiella pneumoniae - 55 (19.2%), Pseudomonas aeruginosa - 35 (12.2%), Escherichia coli - 19 (6.6%). In 2019, the prevailing microorganism was K.pneumoniae - 158 (19.1%). As in 2016, A.baumanii - 115 (13.9%) and P. aeruginosa - 57 (6.9%) were most often found, but unlike 2016, in 2019 there was a high incidence of such pathogens as Enterococcus faecalis - 52 (6.3%), Candida albicans - 43 (5.2%), Staphylococcus aureus and Stenotrophomonas maltophilia - 40 (4.8%). One of the features is the presence of polymicrobial associations. In 2016, microorganisms isolated in monoculture predominated (53.4%), while in 2019 the frequency of occurrence of monocultures decreased and amounted to 24.7%. At the same time, a two-component association prevailed (31.5%). Thus, in ICU it is necessary to regularly monitor nosocomial pathogens not only to make the right decision when choosing antimicrobial therapy, but also to identify new potential nosocomial pathogens.
THE EVALUATION OF HOMOARGININE AND FOLIC ACID IN PATIENTS WITH ARTERIAL HYPERTENSION
Authors: Zhloba A. A. , Subbotina T. F.
Published: July 2020

According to current data, a low level of folic acid (FA) contributes to the progression of arterial hypertension (AH), affecting the metabolism of cells that are involved in the vascular tone regulation, such as hypothalamic astrocytes of nervous tissue. It is also known that the level of FA in the nervous tissue and cerebrospinal fluid is 2-3 times higher than in plasma. There is another metabolic marker of cardiovascular diseases, the level of plasma homoarginine (hArg). The decrease in the level of plasma hArg is also known as a diagnostic sign. In our study, we established that in patients with AH (n = 60), the level of hArg was almost 2 times lower than in healthy individuals, and in 75% of cases the rate was below 1.80 μM. The insufficiency of FA taking into account its low level in plasma FA, as well as the level of total homocysteine (tHcy) higher than 10.9 μM, was observed in 78% of patients. HArg levels at values less than 1.80 μM corresponded to a statistically significant decrease in FA when its content was less than 13.5 nM. This relationship (r = 0.63, p = 0.020) appears in patients with AH, regardless of the number and severity of target organ damage (TOD). FA and hArg as metabolic markers exhibit various diagnostic capabilities when comparing subgroups of patients without TOD and with multiple TOD. Significant differences fared at an acceptable level (p = 0.007) only for the hArg levels, while for the FA concentrations there was only a trend to decrease. It is possible that metabolic disturbances in the central nervous system that are associated with the necessary to maintain high FA concentration contribute to the development of hypertensive status. The causal relationship of a parallel decrease in hArg and FA levels in patients with AH requires further research.
IMPROVEMENT OF BACTERIAL RHINOSINUSITIS DIAGNOSTIC PROCEDURES
Authors: Shmylenko V. A. , Bondarenko A. P. , Trotsenko O. E.
Published: July 2020

The research included evaluation of express-diagnosis capability of immunochromatographic assay (ICA) Binax NOW (Alere, Inc., USA) for diagnosis of the rhinosinusitis caused by to detect the Streptococcus pneumoniae antigen directly in clinical samples. The unique feature of the method included obtaining samples with an electric suction machine in order to evaluate aspirate from deep parts of the nasal cavity. Diagnostic capability of the Binax NOW was determined in a comparative study using classical bacteriological method in 100 clinical samples. Pneumococcus was isolated in 16 patients (16±3,7%) via bacteriological method. ICA utilization allowed to reveal pneumococcal antigen in 20 cases (20±4,0%). ICA test sensitivity equaled 87,5%, specificity - 92,9%. Obtained results allow us to recommend ICA for identification of pneumococcal infection in patients with sinusitis for practicing physicians. The advantages of the evaluated method were fast results (for up to 15 min) and possibility of non-invasive sampling technique of clinical specimens.
X-RAY ENDOVASCULAR OCCLUSION IN ACUTE ARTERIAL BLEEDINGS FROM UPPER PARTS OF THE GASTROINTESTINAL TRACT IN CHILDREN
Authors: Komissarov I. A. , Borisova N. A. , Komissarov M. I. , Aleshin I. Yu.
Published: July 2020

Acute arterial bleeding from the upper gastrointestinal tract (GIT) is a rare and life-threatening condition in children. The main method of instrumental examination in gastrointestinal hemorrhage (GIH) is fibro-esophagogastroduodenoscopy. If endoscopic diagnostics and hemostasis are ineffective, there are used other diagnostic and surgical methods of the treatment, which are associated with a high incidence of complications and high lethality. Methods of X-ray endovascular surgery, such as embolization of the arteries of the gastrointestinal tract, are life-saving and allow avoid severe traumatic surgical intervention. However, reports about the implementation of these methods in children are rare. We examined and treated 12 children with massive upper arterial GIHs. In 6 children it was managed to stop bleeding with the help of conservative and endoscopic methods of hemostasis. In 6 patients, these methods were ineffective, and they were underwent X-ray endovascular occlusion (XREO) of the blood vessels of the digestive tract. In 5 cases, embolization helped stop the bleeding after the first procedure, one child needed a repeat procedure for another source of the localization. In 6 cases, spirals were used as an embolization material, an autohemulation and microemboli were used in a one child patient. There were no complications associated with X-ray endovascular intervention. XREO is a minimally invasive and highly effective method of stopping the massive upper arterial GIH and can be performed even in children in extremely serious condition.
APPROACHES TO THE OPERATIONAL TREATMENT OF CONGENITAL INGUINAL HERNIA AT THE PRESENT STAGE OF THE DEVELOPMENT OF CHILDREN’S SURGERY
Authors: Ten Y. V. , Boyko A. V. , Osetskiy I. G. , Ten K. Yu. , Elkova D. A.
Published: July 2020

Starting this work, the authors set out to highlight the most subtle moments of the classical surgical treatment of congenital inguinal hernias in children, often overlooked in the daily activities of a pediatric surgeon. The article describes the accumulated experience of treating this pathology for the last 7 years, the necessity of an individual choice of the tactics of the management of a child with inguinal hernia has been substantiated. Also, points on which the authors rely on when choosing an open or endoscopic method of treatment are given. There has been raised the problem of training a new generation of pediatric surgeons in connection with the abolition of classical methods of surgery and the ever growing and widespread introduction of endoscopy. The evolution of not only the endoscopic method of treatment, but also the traditional open herniatomy was shown. By means of a method of the retrospective analysis 1410 case histories of patients of the pediatric surgery clinic of the Altai Territory with the diagnosis of inguinal hernia for the period 2010-2017 there were revealed advantages and disadvantages of the methods of treatment, the correlation of relapses with the technique of correction of the disease was established. The ways of the further development of operative methods of the treatment of the non-obliterated vulvar process of the peritoneum are indicated. The paper emphasizes and proves the success of an operation in any method to be depended more on skills of the operating surgeon than on the chosen method. Endoscopic technique, according to the opinion of authors, is preferable in children under 3 years old, in bilateral inguinal hernia, a combination of inguinal and umbilical hernias.
CASE OF MULTIPLE ACUTE SMALL BOWEL PERFORATIONS IN A CHILD AGED 9 MONTHS OLD
Authors: Ignatev E. M. , Efremenkov A. M. , Trunova R. B. , Petrikova N. I. , Snitkin N. A. , Shvedova O. V. , Sokolov Yu. Yu.
Published: July 2020

The article presents the clinical observation of a child 9 months old with multiple perforations of the small intestine, which appeared against the background of acute enteritis of unknown etiology. Long-term surgical treatment was performed. At the first stage, a sanation laparotomy was performed with excision of jejuno- and ileostomy with the intubation of the small intestine. After the reversal phenomena of peritonitis, the closure of the jejunostomy with intubation of the small intestine was performed. The final stage was the closure of ileostomy. The total duration of the treatment is 2 months. A brief review of the literature devoted to multiple perforations of the small intestine in children with a description of the etiology, pathogenesis and treatment of this disease is given.
LAPAROSCOPIC METHOD IN THE FORMATION OF INTERURETERAL PROXIMAL ANASTOMOSIS IN A CHILD WITH VAGINAL ECTOPIA AND URETEROHYDRONEPHROSIS OF THE UPPER SEGMENT OF A DUPLICATED LEFT KIDNEY
Authors: Vrublevskiy S. G. , Poddubnyy I. V. , Shmyrov O. S. , Vrublevskaya E. N. , Lazishvili M. N. , Kulaev A. V. , Korochkin M. V. , Vrublevskiy A. S.
Published: July 2020

The duplication of the urinary tract is a developmental anomaly of the urinary system, which is represented in 0.8% of the population. In most cases, the duplication is incomplete and clinically insignificant. However, in the case of complete duplication, there is possible both an association with such pathologies as ureterocele, vesicoureteral reflux (VUR), urinary incontinence, ureterohydronephrosis and relation to recurrent urinary tract infections. Depending on the identified pathology it is possible to perform surgical interventions. These are organ-displacing operations (heminephroureterectomy) and reconstructive surgery - ureterocystoplasty of the one ureter or both ureters “as a single unit”, as well as the formation of interureteral anastomoses. Currently, there is the possibility to perform both open and endoscopic surgeries. We present a case report of endoscopic minimal invasive reconstructive intervention, performed to patient with ureterohydronephrosis ectopied in the vagina of the urethra of the duplicated left kidney and complaints of urinary incontinence.
ILEAL INTESTINAL DUPLICATION, COMPLICATED BY RECURRENT INTESTINAL BLEEDING AND INTESTINAL OBSTRUCTION. CLINICAL OBSERVATION
Authors: Karaseva O. V. , Kharitonova A. Yu. , Gorelik A. L. , Kislyakov A. N. , Kovalenko M. I.
Published: July 2020

The aim is a demonstration of a rare clinical observation of cystic ileal duplication with a complex diagnostic search of the common source of recurrent bleedings. The boy of 7 years was on the treatment at the Research Institute of Emergency Pediatric Surgery and Traumatology due to frequent recurrent gastrointestinal bleeding. There was performed a comprehensive examination, including laboratory and instrumental methods: common blood and urine test, biochemical blood tests, x-rays of the abdomen, scintigraphy, ultrasound of the abdominal organs, esophagogastroduodenoscopy, colonoscopy, video capsule endoscopic study. Results. The complex diagnostic search was performed. On the basis of the video capsule endoscopic examination and radiography of the abdominal cavity there was suspected the cystic duplication of the ileum with ulcerative defects as the source of bleeding. Upon completion of the examination and relief of post-hemorrhagic anemia there was executed the surgical treatment with resection of the changed area of the intestine and anastomosis “end to end”. The postoperative period was uneventful. Conclusion. Recurrent intestinal bleedings and bowel obstruction can be a complication of such rare malformation of the intestinal tube as the intestinal duplication. The use of modern diagnostic and surgical technology provides timely and minimally invasive treatment that leads to the rapid patient recovery, decline in overall costs and the cost of treatment.
TO THE QUESTION OF EARLY DIAGNOSIS OF ACUTE HEMATOGENOUS OSTEOMYELITIS OF BONES OF THE HIP JOINT IN CHILDREN
Authors: Shamsiev Zh. A. , Shamsiev A. M. , Makhmudov Z. M.
Published: July 2020

Our goal was to develop objective criteria for early diagnosis of acute hematogenous osteomyelitis (AHO) of bones of the hip joint (BHJ)) in children. For the differential diagnosis between AHO and the reactive coxitis (RC) we examined a total of 93 children (61 AHO BHJ and 32 RC cases). AHO BHJ patients are characterized by a higher degree of endogenous intoxication when compared with RC patients. CT allows diagnose AHO BHJ before the appearance of radiological signs (starting from 3 days from the onset of the disease) in the bone tissue and can be used to differentiate AHO BHJ from RC. These features allow using these parameters as objective criteria for the differential diagnosis in children with acutely developed pain in hip joint area
VARICOCELE IN CHILDREN
Authors: Okulov A. B. , Volodko E. A. , Godlevsky D. N. , Mirakov K. K. , Okulov E. A. , Golov I. Yu.
Published: July 2020

The article is devoted to the topical issue - the treatment of one of comon surgical diseases of adolescence - varicocele. We discuss historical aspects of the attitude to the problem and studies carried out in children's surgery in our country, current views on the pathogenesis of the infertility, modern trends in the tactics of observation and treatment of 429 varicocele patients aged 10-18 years. The need for a differentiated approach to the appointment of the examination and treatment, depending on the type of varicocele and concomitant diseases, is considered.
THE USE OF BIODEGRADABLE IMPLANTS IN THE TREATMENT OF JUXTA- AND INTRAARTICULAR FRACTURES IN CHILDREN
Authors: Roshal L. M. , Lushnikov Aleksandr M. , Basargin D. Yu. , Vorobev D. A. , Nikishov S. O.
Published: July 2020

Introduction. In the structure of the general morbidity rate, trauma and diseases of the musculoskeletal system take the third place after diseases of the respiratory system and pathology of the gastrointestinal tract. In recent years, an intensive indices characterizing the trauma prevalence rate has increased by 1.9 times. Aim. to improve the results of the management of juxta- and intraarticular fractures in children by means of the use of biodegradable implants. Material and methods. Over the period from 2014 to 2016 in the Department of Traumatology of the Research Institute of Emergency Pediatric Surgery and Traumatology there were examined and treated 108 children with juxta- and intra-articular fractures of the upper and lower extremities aged from 5 to 17 years, with an average age of 13.3 ± 1.8, including 38 (34.96 %) girls and 70 (65.04%) boys. All patients underwent complex examination including laboratory and instrumental methods: complete blood count (CBC), Common Urine Examination (CUE), X-Ray, spiral computed tomography, MRI. Results. To describe injuries and determine the tactics of the treatment of juxta- and intra-articular fractures in children, there was used the fracture classification system delivered by Robert B. Salter and W. Robert Harris. All children with metaphyseal fractures of the second, third, and fourth types underwent surgical treatment with the use of biodegradable implants. The postoperative period proceeded without complications. Conclusion. The use of biodegradable screws in juxta- and intra-articular fractures in children is a safe and effective method of treatment, reducing its timing by eliminating repeated surgical intervention.
SURGICAL TREATMENT OF THE CYSTIC ADENOMATOUS PULMONARY MALFORMATION IN CHILDREN
Authors: Chepurnoy G. I. , Katsupeev V. B. , Chepurnoy Mikhail G. , Karagezyan R. L. , Leyga A. V. , Matveev O. L. , Pechkurov S. A.
Published: July 2020

There is presented the analysis of 13 patients with polycystic lung disease. In the diagnosis of the disease, spiral computed tomography has a decisive importance. The technique of performing surgical interventions aimed at maximum preservation of healthy lung tissue is described in detail. The excision of cystic membranes and reliable suturing of bronchial fistulas determines the radicality of surgical interventions that provided favorable outcomes in the long term after operations in all patients.
THE CLINICAL CASE OF THE SURGICAL TREATMENT OF CYSTIC LYMPHANGIOMA OF THE COMPLEX ANATOMICAL LOCALIZATION IN CHILD AGED OF 1 YEAR 7 MONTHS
Authors: Poddubnyy I. V. , Ryabov A. B. , Trunov V. O. , Kozlov M. Yu. , Topilin O. G. , Manukyan S. R. , Mordvin P. A. , Tverdov I. V.
Published: July 2020

Lymphangiomas are non-specific formations developing from the lymphatic vessels, occupying an intermediate position between the tumor and the developmental malformation. The most frequent localization of the pathology is the face and neck area (75%) and the axillary region (20%), less than 1% of cases are located in the mediastinum. According to the literature data, the only radical treatment is surgical, but there is a high prevalence rate of relapses (25%). This article is devoted to the analysis of the clinical case of the treatment of lymphangioma of the complex anatomical localization, reflecting the complexity of the diagnosis and radical relapse-free treatment of this pathology.
ANESTHESIA MANAGEMENT FOR COCHLEAR IMPLANTATIONS IN PEDIATRIC PATIENTS
Authors: Kalugina M. S. , Aleksandrov A. E. , Alekseeva E. A. , Rusetskiy Yu. Yu.
Published: July 2020

For the time present, the cochlear implantation is a widely used method of the treatment of deafness and severe hearing impairment. The operation is time-consuming and requires a long stay of the child in the hospital. The placement of the cochlear implant (CI) is executed under general anesthesia through transosseous access. The executive work of the surgical and anesthetic teams is an integral part of the successful implementation of intraoperative CI testing, on the base of results of which, in the postoperative period, there will be carried out the initial adjustment of the speech processor. An anesthesiologist should create conditions that facilitate the use of nerve stimulators in the intraoperative period and in a timely manner prevent such common postoperative complications as nausea, vomiting, and dizziness. This article provides a review of the literature of domestic and foreign authors on the issues arising in anesthesiologists during the implementation of cochlear implantations and the ways of their solutions. It is considered what difficulties can arise during the installation and initial adjustment of CI, as well as what anesthesia complications are most frequent in operations of this type. After studying the results of the work of different authors, the initial adjustment of the CI in the anesthetic management under the control of BIS and TOF monitoring was concluded to be performed at a higher level, and the timely and targeted administration of various drugs, at certain stages of anesthesia, contributed to the decline of the complications rate in the postoperative period.
LAPAROSCOPIC INTERVENTIONS IN CHILDREN WITH CONGENITAL DUODENAL DIVERTICULA
Authors: Sokolov Yu. Yu. , Efremenkov A. M. , Akopyan M. K. , Ignatev E. M. , Zykin A. P. , Chernikov A. N. , Utkina T. V.
Published: July 2020

Duodenal Diverticula (DD) are referred to rare clinical observations in pediatric practice. The article presents two clinical cases of extra-luminal true DD in children. There is described an experience of using laparoscopy in the treatment of a combined anomaly of the bile ducts and cysts of choledochus and DD in a child of 10 years and an extraluminal DD in a child of 12 years.
PECULIARITIES OF SURGICAL TREATMENT OF THYROID GLAND IN CHILDREN
Authors: Ten Yu. V. , Krasilnikov A. A. , Ten Y. V. , Yelkova D. A.
Published: July 2020

The pediatric surgeon in his work has to face a wide variety of diseases related to narrow areas of medicine. Particular difficulties are caused by the diagnosis and treatment of thyroid gland formations (TGF). The number of such patients is steadily growing both in the Russian Federation and in the Altai Territory, due to iodine deficiency, radiological and environmental pollution and other possible causes. In the Children’s Surgery Clinic of the Altai State Medical University, 101 children aged from 5 to 17 years were treated in the period from 2000 to 2017 due to thyroid lesions. The study included operated patients with both benign formations and with follicular and papillary carcinoma:. Depending on the case, a different volume of surgical intervention was used: mainly, hemithyroidectomy with isthmectomy and total thyroidectomy. In the work the analysis of own results of the treatment is carried out, comparison with widely known approaches of the management of patients with TGF is given. We are of the opinion that the desire for radicalism does not always yield the best results. Thus, we consider it quite justified to perform organ-preserving operations in both follicular and papillary thyroid carcinoma. Difficulties in deciding the extent of the intervention are also caused by the inability to differentiate the form of thyroid mass before the operation. In addition, the hormonal status of the child in the postoperative period requires special attention, and the use of hormonal therapy in the absence of hormonal disorders pushes to doubt its necessity. A number of features in the operational process allows achieving good results. Thus, the choice of tactics for treating children with thyroid disorders should be advisedly and carefully considered taking into account the characteristics of the child’s organism and the specific situation.
MULTISPIRAL COMPUTER TOMOGRAPHY IN DIAGNOSTICS OF ACUTE SKELETAL INJURIES IN CHILDREN
Authors: Korneev I. A. , Akhadov T. A. , Semenova N. A. , Melnikov I. A. , Nikishov S. O. , Serova N. Yu. , Menshchikov P. E. , Manzhurtsev A. V. , Dmitrenko D. M. , Roshal L. M. , Ublinsky M. V.
Published: July 2020

Multi-sliced computed tomography (MSCT) is widely used to study patients with polytrauma, especially when assessing skeletal and spinal injuries as it has provided possible volume visualization. MSCT has long been used to diagnose injuries of pelvic bones and the spine. For the examination of limb injuries, it is used rarely until now. Although traditionally used radiography often underestimates degree and severity of damages, especially in the complex body parts such as shoulder, elbow, wrist, knee and ankle joints. The role of MSCT is extremely important to identify complex and small fractures, their nature and evaluation, planning of treatment. Multiplanar reconstruction clearly visualizes structural features, and three-dimensional images help to understand spatial relationships, which is important for pre-operative planning and classification of fractures. In addition, modern technologies for suppressing metal artifacts in MSCT allow monitoring postoperative results even in the presence of metal implants.
CLINICO-ANATOMICAL FEATURES OF INTEGUMENTARY TISSUES IN THE ACHILLES TENDON FROM THE POINT OF VIEW OF PLASTIC SURGERY. THE ANALYSIS OF WAYS OF ELIMINATION OF CICATRICIAL DEFORMATIONS IN THE ACHILLES TENDON AREA: THEIR ADVANTAGES, DISADVANTAGES
Authors: Filippova O. V. , Govorov A. V. , Afonichev K. A. , Galkina N. S. , Proshchenko Ya. N. , Nikitin M. S.
Published: July 2020

The article deals with the features of integumentary tissues in the Achilles tendon region, which must be taken into account in the planning of reconstructive surgeries, the clinical features of this scar localization, as well as the advantages and disadvantages of existing methods of normal skin repair in the Achilles tendon area.
CLINICAL OBSERVATION OF A FAVORABLE OUTCOME AFTER SEVERE INJURY DUE TO THE FALL FROM THE SIXTEENTH STOREY
Authors: Bagaev V. G. , Timofeeva A. V. , Amcheslavsky V. G. , Ivanova T. F. , Bykov M. V. , Shevchuk A. M. , Kolykhalkina I. A. , Melnikov I. A. , Bagayeva Yu. V. , Roshal L. M.
Published: July 2020

Introduction. Catatrauma is one of the main causes of childhood injuries and deaths in Russia. The severity of the condition of catatrauma is caused by combined injuries, high disability and lethality depend on them. Most often, children fall from the balconies of houses, windows, trees, and playgrounds. The purpose of the study was to show, on a clinical example, the case of a fall of a child from the height of the 16th storey of a dwelling house and the survival with a favorable outcome. Material and methods. The clinical example demonstrates the provision of medical care to a 5 years old child with catatrauma in a metropolis. After falling from a critical height (48 m) at the prehospital stage, he was assisted by ambulance brigades, and transportation was carried out by a helicopter. At the hospital stage, the victim was treated at the Research Institute of Emergency Surgery and Traumatology, where all departments of the clinic were involved. Results. This clinical case is unique in that the child, having fallen from the 16th sorey, from a height of more than 48 m, having received multiple combined injuries with an ISS score of 34 points, survived. An outcome was favorable due to the fact that the child was dressed in winter clothes with a jacket hooded over his head and fell into the snow, as well as coordinated actions of the services and units providing medical care at the prehospital and hospital stages in the metropolis. Conclusion. A favorable outcome after the child had fallen from a critical height, was affected by facts that both the child was dressed in winter clothes with a hood and a hat, put on the head, falling into the snow, and the coordinated activity of the structures and units participating in the prehospital and hospital stages of medical care.
Antimicrobial activitiy of oak honey (Quercus spp.) on the biofilm microorganisms
Authors: ÖZKIRIM Aslı , SCHİESSER Aygün , KÜÇÜKÖZMEN Billur , İPEK Ahmet , SORKUN Kadriye
Published: July 2020

Objective: The aim of this study is to determine antimicrobial properties of oak honey on biofilm microorganisms and its potential usage. Material and Methods: The oak honey was collected in 2 years from the same region (OHPH/OHSH). Susceptibility patterns of clinical strains of three bacteria (Escherichia coli-ATCC 35218), (Staphyllococcus aureus-ATCC 29213) , (Pseudomonas aeruginosa -ATCC 27853) and one yeast (Candida albicans -ATCC 10231) strains that can form biofilm communities to oak honey were assessed by the disc diffusion method. Results: The results revealed that oak honey has high level of antimicrobial activity to the pathogens. The antifungal activity against C. albicans was not measured clearly though, bacteriostatic effect showed itself as a secondary zone. Conclusion: Oak honey might have a big potential for its antimicrobial properties in near future.
THE EFFECT OF MACROECONOMIC VARIABLES ON FISCAL SUSTAINABILITY IN INDONESIA, PERIOD 2004Q1-2018Q4
Authors: Abdullah Muhammad Latif , Sunaryati FNU
Published: July 2020

Abstract Fiscal sustainability illustrates the condition of a healthy government budget which can finance government spending without increasing debt supply. The purpose of this study is to analyze the impact of macroeconomic variables on fiscal sustainability which in this study fiscal sustainability is proxied as a government budget deficit. The data used in this study is the 2004Q1-2018Q4 time series data using the Vector Error Correction Model (VECM). The results showed that fiscal conditions in Indonesia are sustainable and macroeconomic variables such as domestic debt andinflation has a positive effect on increasing the government budget deficit. Whereas the variable state revenues and foreign debt negatively affect the government budget deficit.Keywords : Fiscal Sustainability, Government Budget Deficit, Domestic Debt, Foreign Debt.
Results of the all-Russian scientific and practical conference “Information context of culture: resources, technologies, services”, September 24–25, 2019
Authors: Sukhotina M. L.
Published: July 2020

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K. I. Abramov’s contribution to the development of the methodology of library history: historical reconstruction
Authors: Pleshkevich E. A.
Published: July 2020

The article is devoted to the contribution of the famous Russian specialist in library science K. I. Abramov to the methodology of library history, the author of almost 340 publications, of which two-thirds are devoted to history. The importance of his contribution to the development of source studies, historiography, archeography, and library history is emphasized. Based on the principle of historicism and methods of structural analysis, the historical reconstruction of the formation and development of his methodological views was carried out. The external conditions of his formation as a historian are analyzed. It is noted that the formation took place in difficult socio-political conditions. The main conclusions are as follows. The methodological views of K. I. Abramov were based on the relying on archival material, striving to improve the scientific character of historical research, overcoming the desire to reduce research to a superficial presentation and commentary on certain Leninist positions. With his participation, Lenin and Krupskaya’s works on library science were collected and published. At the same time, his worldview was characterized by a dogmatic attitude to Marxism and its methodology, an unconditional adherence to the leading quote, and a non-critical attitude to the statements of the classics of Marxism-Leninism. The Marxist-Leninist doctrine of culture and the library heritage of Lenin and Krupskaya served as a theory in Abramov’s works; the dominance of historical and pedagogical research, which is characterized by following the official interpretation of certain events, simplified presentation of historical processes and events, unambiguity of author’s judgments and assessments, avoiding halftones, exalting achievements while concealing mistakes and failures.

The analysis also showed that in the 1990s, under the influence of socio-political changes and rejection of Marxism-Leninism, Abramov revised his attitude to the history of Soviet library construction. He began to focus on the theory of democracy, in the context of which libraries were seen as a vehicle for democracy, and the leading role in library construction was given to the public library movement. He puts forward the concept of democratic library science, which was formed in the period between the February and October revolutions and was rejected by the Bolsheviks.

The significance of this study is associated with the generalization of Abramov’s methodological heritage aimed at developing the positive aspects of his methodology, as well as overcoming methodologically incorrect judgments about the history of Soviet library construction.
Bibliometric analysis of the research activity efficiency of the Fiber Optics Research Center of the RAS
Authors: Kochergina T. A. , Iskhakova L. D. , Mashinsky V. M. , Semjonov S. L.
Published: July 2020

Russian scientific organizations rating system introduction at the state level makes the use of scientometric indicators necessary. This article is devoted to the problems of analysis and improving the scientific activities effectiveness of the organization. The aim of this work is to present the bibliometric analysis results of the research activities of the Fiber Optics Research Center of the Russian Academy of Sciences (FORC RAS). The assessment of the contribution of the FORC RAS to the development of fiber optics as a scientific field is given. The main scientometric indicators were studied: publication activity, the total number of scientific papers citations and normalized citation, the number of the most highly cited articles, Hirsch indices. The comparison of bibliometric indicators of the FORC RAS with other Russian scientific organizations working in the fiber optics field was carried out. The performed analysis is relevant both to characterize the FORC RAS activities and to choose the library activity direction. The methodological approach is based on the application of mathematical, bibliographic and bibliometric research methods. The analysis was carried out using the Russian Science Citation Index (RSCI), scientometric databases Web of Science and Scopus, as well as the InCites analytical tool. The relationship between meeting the needs for scientific information of scientists and increasing the efficiency and success of research activities of a scientific organization is shown. The main source of information at the present stage is the access of research organizations to the scientific electronic resources of leading world publishers. In this work, the authors conclude that new forms of library work, consisting in creating your own information resource “Fiber Optics Information System”, which contains both an electronic library of publications in this subject area, and complete information about the work of employees, are very promising.
Discovery layer decisions, configurations and strategies
Authors: Schwartz R.
Published: July 2020

The problem that patrons frequently encounter with searching via a discovery layer linked to a knowledgebase is the overwhelming number of hits. Few if any research or discussion compares how libraries resolve this difficulty. To begin a discussion, the author disseminated an open invitation for academic libraries to participate on three panels from October 2018 to June 2019 to discuss their implementation processes and decisions. Five academic libraries accepted the invitation. This paper reviews the approaches of the five American academic library systems with the intent to encourage further examination of the issues of design, implementation, and maintenance of discovery layers. The conclusions reached point to the evolving nature of discovery layer interfaces and the struggle for libraries to adapt their needs to this still changing product type. Within this group, the larger institutions with more financial and staff resources have designed a ‘’bento box’’ interface with open source software, while the other institutions with lesser means have chosen to create different instances of their subscribed proprietary discovery layers to meet their specific institutional demands and the specific needs of their patrons. A statistically relevant examination with rigorous comparison of usability testing would have to be done to see how these and other factors play out in the wider field.
PELATIHAN PENGOLAHAN SAMPAH DALAM MENINGKATKATKAN LIFE SKILL PADA KOMUNITAS PEDAGANG RUJAK BUAH DI KLENDER JAKARTA TIMUR
Authors: Sasmita Karta
Published: July 2020

ABSTRAK: Penelitian ini bertujuan untukmemberikan pengetahuan dan pemahaman melalui Pelatihan pengolahan sampah dalam meningkatkan life skill pada komunitas pedagang rujak buah di RT.013/RW.003 Kelurahan Klender. Pada penelitian ini diperoleh masalah bahwa komunitas pedagang rujak buah di RT 013 RW 03 Klender belum memiliki life skill bagaimana cara mengolah sampah. Sehingga diperlukan upaya berupa pelatihan pengolahan sampah untuk dapat meningkatkan life skill pada komunitas pedagang rujak buah tersebut. Dari penelitian ditarik kesimpulan bahwa pedagang rujak buah mempunyai life skill pengolahan sampah untuk menangani masalah sampah, sehingga tidak banyak sampah lagi yang diproduksi di lingkungan RT 013 RW 003, dengan demikian, maka tidak akan timbul permasalahan yang berkaitan dengan sampah. Adapun hasil pelatihan berupa produk kompos cair dan komposter yang dipakai oleh peserta untuk penghijauan.
LIVING QUR’AN: KHATAMAN SEBAGAI UPAYA SANTRI DALAM MELESTARIKAN AL-QUR’AN
Authors: Maghfiroh Elly
Published: July 2020

Islam adalah agama rahmatal lil 'alamin, di mana semua ajarannya disediakan untuk semua makhluk bumi. Sedangkan Al-Qur'an adalah kitab suci umat Islam yang membimbing dan menjadi orientasi dalam setiap kehidupan. Oleh karena itu, ada begitu banyak ekspresi kaum muslimin dalam Al-Qur'an dalam praktek sehari-hari. Kadang-kadang Al-Qur'an menjadi pedoman dalam bertindak, menyelamatkan dalam melindungi diri sendiri, menyangkal gangguan setan atau membaca dalam kehidupan sehari-hari kaum muslimin. Oleh karena itu dapat dikatakan bahwa Al-Qur'an bukan hanya teks pasif tetapi juga teks hidup di tengah komunitas muslim. Salah satu fenomena ini adalah tradisi khataman di Pondok Pesantren Al-Munawwir Krapyak Yogyakarta, di mana terlihat bahwa membaca Al-Qur'an menjadi nafas dalam kegiatan tersebut. Atas dasar itu, tulisan ini akan menggambarkan fenomena masyarakat dalam melestarikan Al-Qur'an yang ada di Khatmil Qur’an di Pondok Pesantren Al-Munawwir Krapyak Yogyakarta. Pada saat yang sama, untuk mengetahui arti aries dari acara Khatmil Qur’an. Studi ini penting, qur'an yang hidup sebagai studi baru dalam studi qur'an mencoba untuk menginterpretasikan penerimaan komunitas Al-Qur'an dengan interkoneksi dengan ilmu sosial, salah satunya adalah sosiologi pengetahuan.
KRITIK NALAR ISLAM (STUDI PEMIKIRAN HERMENEUTIK MOHAMMED ARKOUN)
Authors: Ulya Inayatul
Published: July 2020

Mohammed Arkoun dengan kritik nalar Islamnya memiliki corak baru dalam dinamika Hermeneutika. Bagi Arkoun, perkembangan zaman telah menyisakan persoalan-persoalan keagamaan yang tidak cukup diselesaikan dengan pemahaman agama secara dogmatis dan a historis, akan tetapi diperlukan pemikiran Islam kontemporer dan berbagai pendekatan untuk memahami ajaran Islam agar terlepas dari belenggu ideologis dari pemikiran ulama’ sebelumnya. Maka, untuk merealisasikan hal ini diperlukan sebuah pendekatan pemikiran yang kemudian dikenal Kritik Nalar Islam. Arkoun, dalam hal ini berusaha memperkenalkan pendekatan pemikiran hermeneutika sebagai metodologi kritis yang akan memberikan pemahaman dan pemaknaan baru dalam memahami teks. Pendekatan historis-kontekstual diperlukan untuk mentransformasikan pemaknaan ajaran agama agar selalu relevan dengan perkembangan zaman.
PERSPEKTIF AL-SYAWKANI TENTANG PENTARJIHAN PERBEDAAN PENAFSIRAN
Authors: Atabik Ahmad
Published: July 2020

Tarjîh  dalam penafsiran dihasilkan dari adanya berbagai perbedaan pendapat para mufassir dalam menafsirkan ayat-ayat al-Qur’an. Tujuannya adalah mengetahui pendapat yang paling sahih dan paling layak diterima dalam penafsiran al-Qur’an untuk dapat diamalkan sesuai bidangnya. Tujuan lain, peniadakan kitab-kitab tafsir dari pendapat-pendapat yang janggal dan lemah atau pendapat yang rancu yang disusupkan oleh keyakian mazhab tertentu. Di antara mufassir yang memberi perhatian pada aspek tarjîh  dalam penafsirannya adalah Imam al-Shawkânî. Dalam menafsirkan ayat-ayat al-Qur’an, ia tidak cukup hanya menyuguhkan pendapat-pendapat mufassir sebelumnya, melainkan juga melakukan tarjîh terhadap penafsiran-penafsiran itu. Dalam hal ini ia menetapkan seperangkat kriteria dan metode tertentu dalam proses pentarjîh}an terhadap berbagai pendapat yang dikemukakan para ulama. Hasil penelitian ini menemukan bahwa al-Shawkânî dalam mentarjîh perbedaan penafsiran menggunakan metode yang meliputi 1) sîghat (redaksi yang tertentu yang digunakan dalam mentarjîh), 2) teknik tarjîh yang dilakukan al-Shawkânî sendiri dan tarjîh yang diambil dari pendapat ulama’ lain), dan 3) bentuk (tarjîh) dengan naz}âiral-Qur’ân, dengan sunnah, dengan qirâ’ât dan lainnya). Di akhir, makalah ini juga mengeksplorasikan aplikasi dan contoh tarjîh dari metode al-Shawkânî tersebut, dengan tujuan dapat memudahkan bagi pembaca agar lebih jelas memahami metode tarjîhnya.
MUDARASAH AL-QUR’AN SEBAGAI DIALOG SANTRI TAHFIDZ DENGAN AL-QUR’AN DALAM MENJAGA HAFALAN (STUDI LIVING AL-QUR’AN)
Authors: Zaenuri Zaenuri , T. Abdullah
Published: July 2020

Kehadiran al-Qur’an di tengah-tengahn masyarakat menimbulkan kewajiban mempelajarinya dan bermacam variasi respon terhadapnya. Al-Qur’an yang sakral merupakan mukjizat Nabi Muhammad SAW melalui perantara Malaikat Jibril dan barang siapa yang membacanya bernilaisuatu ibadah. Al-Qur’an adalah kitab suci yang diturunkan oleh Allah SWT kepada hambanya yang dijaga kemurniannya dari pengurangan, penambahan dan penggantian huruf. Mengenai cara menjaga al-Qur’an, sebagaimana yang telah dicontohkan oleh Rasulullah yaitu dengan cara menghafal. Dengan melihat pentingnya menghafal al-Qur’an, maka dewasa ini banyak orang yang berlomba-lomba dalam menghafal al-Qur’an, bahkan dalam menempuh hafalannya membutuhkan waktu yang tidak relatif lama. Adapun temuan penulis adalah mudarasah al-Qur’an sebagai wujud terima kasih kepada Allah yang telah memberikan karunia sehingga mampu menghafalkan al-Qur’an, selain itu juga sebagai kewajiban bagi para penghafal al-Qur’an untuk menjaganya yang apabila melupakannya mendapat dosa. Kemudian keutamaan al-Qur’an sebagai bentuk kemuliaan yang diberikan oleh Allah kepada hamba yang mau menghafalnya, dimaksudkan supaya meluruskan niat dengan keutamaan yang dijanjikan Allah, sebab menghafal al-Qur’an tentu banyak hambatan-hambatan yang akan dilalui oleh para penghafal al-Qur’an dalam mencapai puncak kemuliaan. Jika niat sudah lurus dan benar, maka ketika proses menghafal al-Qur’an tidak akan mudah goyah dengan berbagai rintangannya.
РОЛЬ ДЕЗИНТОКСИКАЦИОННОЙ И АНТИОКСИДАНТНОЙ ТЕРАПИИ В ЛЕЧЕНИИ COVID-19: ТЕОРИЯ И ПРАКТИКА
Authors: Хавкина Дарья , Руженцова Татьяна , Чухляев Павел , Гарбузов Александр , Шушакова Екатерина
Published: July 2020

Проанализировано более 30 литературных источников, содержащих данные о течении, диагностике и терапии Covid-19. Ни в одном источнике не упоминается о дезинтоксикационной и/или антиоксидантной терапии. Проанализированы три клинических случая COVID-19. На основе собственной клинической практики сформирована модель патогенеза COVID-19, которая обосновывает необходимость применения препаратов – дезинтоксикантов, сорбентов и антиоксидантов, как улучшающих течение, прогноз и исход заболевания. Клинические примеры, указанные в статье демонстрируют эффективность предложенной терапии. Сформированная модель патогенеза COVID-19 обоснована клинически и патофизиологически.
Anaphylactic Reaction to Tranexamic Acid During Posterior Spinal Fusion
Authors: Plaster Scott , Holy Filip , Antony Antony Kallur
Published: July 2020

Case:

We present a 20-year-old man who suffered anaphylactic shock during posterior spinal fusion for neuromuscular scoliosis with the offending agent later identified via intradermal testing to be tranexamic acid (TXA).

Conclusion:

TXA, although an increasingly common drug, can be the cause of sudden anaphylactic shock intraoperatively. This now represents the fifth reported case in the literature of patients ranging from 15 years to 80 years old with no previous exposure to the drug.
Is limited aortic resection more justified in elderly patients with type A acute aortic dissection?
Authors: Qin Wei , Su Cunhua , Li Liangpeng , Carmichael Michael , Huang Fuahua , Chen Xin
Published: July 2020

Background: This study compared limited aortic repair (ascending, and /or hemi-arch replacement) versus extended-arch repair (ascending, arch and proximal descending aortic replacement) used for patients aged 65 or older, who had type A acute aortic dissection (AAD), analyzing the influence of the extent of aortic repair on outcomes.Methods: From January, 2001 to December, 2015, 103 patients aged 65 or older underwent operation due to type A AAD in Nanjing First Hospital. The cohort was divided into two subgroups according to the surgical approaches, including limited aortic replacement (LAR, n=41) and total arch replacement + stent elephant trunk implantation (TAR+SET, n=62). Results: There was no significant difference in gender, age, hypertension, diabetes, smoking, PCI history, atrial fibrillation, pericardial effusion, aortic valve insufficiency (≥ moderate), shock situation before operation, and Euro-score II between the two groups except limb malperfusion and tear location. The cross-clamp time, CPB time, intubation time, ICU stay time and hospital time were all significantly less in the LAR group than in the TAR+SET group. A total of 89 patients were discharged home successfully after operation, with a difference of hospital mortality (P=0.04). The overall survival rates at 5-year follow-up were 82.5±6.0% in LAR group and 75.2±5.6% in TAR+SET group, but with no difference (p=0.151). The freedom from adverse aortic events at 5-year was 84.3±6.5% in LAR group versus 97.9±2.1% in TAR+SET group, with a statistical difference (p=0.03). Conclusion: These findings support limited aortic resection is acceptable for elderly patients with type A AAD if surgical principles allow.
Cerebrospinal fluid α-synuclein predicts neurodegeneration and clinical progression in non-demented elders
Authors: Li Jie-Qiong , Bi Yan-Lin , Shen Xue-Ning , Wang Hui-Fu , Xu Wei , Tan Chen-Chen , Dong Qiang , Wang Yan-Jiang , Tan Lan , Yu Jin-Tai
Published: July 2020

Background: Accumulating reports suggest that α-synuclein is involved in Alzheimer disease (AD) pathogenesis. Cerebrospinal fluid (CSF) α-synuclein could be a potential biomarker of AD. We sought to test whether CSF α-synuclein is associated with other AD biomarkers and could predict neurodegeneration and clinical progression in non-demented elders. Methods: Associations were investigated between CSF α-synuclein and other AD biomarkers at baseline in non-demented Chinese elders. The predictive values of CSF α-synuclein in longitudinal neuroimaging change and conversion risk of non-demented elders were assessed using linear mixed effects models and multivariate Cox proportional hazard models, respectively, in Alzheimer's disease Neuroimaging Initiative (ADNI) database.Results: We detected that CSF α-synuclein levels correlated with AD-specific biomarkers CSF total tau and phosphorylated tau levels in 651 Chinese Han participants (training set). These positive correlations were replicated in ADNI database (validation set). Using a longitudinal cohort from ADNI, CSF α-synuclein concentrations increased with disease severity. CSF α-synuclein had high diagnostic accuracy for AD based on the “ATN” system (A+T+) vs controls (A-T-) (area under the receiver operating characteristic curve, 0.84). Moreover, CSF α-synuclein predicted longitudinal hippocampus atrophy and conversion from MCI to AD dementia.Conclusions: CSF α-synuclein is associated with CSF tau levels and could predict neurodegeneration and clinical progression in non-demented elders. This finding indicates CSF α-synuclein is a potentially useful, early biomarker for AD.