bluuebunny/crossref_metadata_2025 huggingface dataset:
Does the government procurement market favor corporate social responsibility in a weak institution? Evidence from China
Authors: Rong Ran , Qiqi Wang , Zhiyang Liu , Shaobo Long
Published: December 2022

This study investigates, in the context of a weak institution, the single and interactive effects of firms’ nonmarket strategies in China’s government procurement market. Based on transaction cost and signal theory, using data pertaining to Chinese government procurement contracts from 2016 to 2018, this study also provides evidence that superior corporate social responsibility (CSR) performance enables firms to obtain more government procurement contracts. However, the effect is only significant in non-state-owned enterprises. Considering the interaction effect of corporate political activity (CPA) and CSR in business to government (B2G) markets, this study finds that CPA, characterized by the political attributes of executives, enhances the signal effect of CSR in B2G markets. Further heterogeneity analysis indicates that CSR’s signal effect diminishes over time and is enhanced with high industry competition. Our findings provide new insights on nonmarket mechanisms (such as CSR), through which firms competing in China’s B2G market can compensate for the weak institution.
Gut colonization by Bacteroides requires translation by an EF‐G paralog lacking GTPase activity
Authors: Han Weiwei , Peng Bee‐Zen , Wang Chunyan , Townsend Guy E , Barry Natasha A , Peske Frank , Goodman Andrew L , Liu Jun , Rodnina Marina V , Groisman Eduardo A
Published: December 2022

Protein synthesis is crucial for cell growth and survival yet one of the most energy‐consuming cellular processes. How, then, do cells sustain protein synthesis under starvation conditions when energy is limited? To accelerate the translocation of mRNA–tRNAs through the ribosome, bacterial elongation factor G (EF‐G) hydrolyzes energy‐rich guanosine triphosphate (GTP) for every amino acid incorporated into a protein. Here, we identify an EF‐G paralog—EF‐G2—that supports translocation without hydrolyzing GTP in the gut commensal bacterium Bacteroides thetaiotaomicron. EF‐G2's singular ability to sustain protein synthesis, albeit at slow rates, is crucial for bacterial gut colonization. EF‐G2 is ~10‐fold more abundant than canonical EF‐G1 in bacteria harvested from murine ceca and, unlike EF‐G1, specifically accumulates during carbon starvation. Moreover, we uncover a 26‐residue region unique to EF‐G2 that is essential for protein synthesis, EF‐G2 dissociation from the ribosome, and responsible for the absence of GTPase activity. Our findings reveal how cells curb energy consumption while maintaining protein synthesis to advance fitness in nutrient‐fluctuating environments.
Nuevos registros y datos morfométricos y merísticos del conejo de hondura, Sphoeroides pachygaster (Tetraodontiformes: Tetraodontidae), en el suroeste del golfo de México
Authors: Del Moral-Flores Luis Fernando , Castro-Martínez Alondra Jazmín
Published: December 2022

The objective of this contribution is to present new records of the occurrence of Sphoeroides pachygaster, based on 8 specimens deposited in a scientific collection of 175-313 mm in standard length weighing 178.7-1 010 g, which were captured south of Veracruz, southwestern Gulf of Mexico. In addition, meristic and morphometric data of the captured specimens are given and discussed as support for identification.
Nuevos registros de Epidendrum (Orchidaceae) para Colombia: Epidendrum porphyreonocturnum Hágsater & R. Jiménez y Epidendrum whittenii Hágsater & Dodson
Authors: Perdomo Oscar , Coca Luís Fernando , Trujillo Trujillo Edwin
Published: December 2022

Reportamos por primera vez para Colombia Epidendrum porphyreonocturnum Hágsater & R. Jiménez y Epidendrum whittenii Hágsater & Dodson, dos especies de orquídeas encontradas en el Piedemonte Andino-Amazónico del departamento de Caquetá. Estas especies eran previamente conocidas solo de Ecuador y Perú. Las dos especies fueron categorizadas como Vulnerables de acuerdo con los criterios de la IUCN debido a las amenazas sobre su hábitat y el bajo número de poblaciones conocidas. Estos reportes enriquecen el conocimiento de la orquideoflora colombiana y resaltan la necesidad de realizar mayores esfuerzos en pro del conocimiento y la conservación del piedemonte.
METHODS OF RADIO FREQUENCY INTERFERENCE MITIGATION ON THE STAGE OF PRELIMINARY PROCESSING OF RECEIVED SIGNALS
Authors:   Institute of Radio Astronomy of the National Academy of Sciences of Ukraine, Stanislavsky L.
Published: December 2022

Subject and Purpose.Methods for computer processing of radio astronomical signals observed with space objects at low frequencies are given. The aim of this paper is to improve the current methods and use their combinations for cleaning records from radio interference of natural and artificial origin in the frequency-time domain, as well as to discuss advantages and disadvantage of the methods. Methods and Methodology.In the study of records obtained with radio astronomical observations there is a common feature of received signals from space sources, which consists in a significant contribution of radio interference. Having sufficient experience on possible types of interference and distortion of signals on the way of their propagation, the efficiency of suggested procedures, clearing radio signal interference in the frequency-time domain by a combination of different approaches in dependence from typical features of signals withinvestigated space objects, is shown. Results. The developed methods of extracting space signals against the background of interference allow one to get unique data on the sources of radio emission in astrophysical phenomena. On the one hand, software tools make it possible to detect very weak events against the background of radio frequency interference. On the other hand, they allow one to measureemission parameters based on the most statistically complete set of events. Conclusions.The results obtained in this work manifest that there is no universal way to overcome any obstacle in the records of radio astronomical observations because of radio interference. In addition, even if the most appropriate method is applied, it often requires pre-adjustment of the corresponding parameters on which the analysis of physical parameters of radio emission in the area of generation depends. But if such a space signal at the radio records is not very spoiled by interference, the use of considered methods can be successful and useful.
Determinan Tingkat Efisiensi Perbankan di Indonesia
Authors: Tika Sari Veronika Cindy Mey , Nurhayati Puji , Dzuralda Tiya
Published: December 2022

Indonesia is a country with the existence of a Sharia banking sector that operates side by side with conventional banks under the supervision of Bank Indonesia which is quite a lot. The existence of Islamic banking needs to be measured efficiency in measuring the resilience of its market share. This study aims to determine the factors that affect the level of efficiency of Islamic banking in Indonesia for the period 2010-2021, which is projected with Non Performing Loan (NPL), size, Capital Adequency Ratio (CAR), Return On Assets (ROA), Financing to Deposit Ratio (FDR). The data used is secondary data in the form of islamic banking annual reports. This research sample is Sharia Commercial Bank as many as 7 Banks. Sampling techniques are carried out using purposive sampling. Data analysis techniques use multiple linear regression analysis with SPSS v.18. The results showed that Non Performing Loans (NPL), size, and Return On Assets (ROA) affected the bank’s efficiency rate. Meanwhile, Capital Adequency Ratio (CAR) and Financing to Deposit Ratio (FDR) have no effect on the bank’s efficiency level.
Kepemilikan Institusional Memoderasi Pengaruh Transaksi Hubungan Istimewa Terhadap Penghindaran Pajak
Authors: Murwaningsari Etty , Rachmawati Sistya
Published: December 2022

Aspects of sales, purchases, and related credit as well as taxation, especially tax avoidance and institutional ownership, are important information for the company’s stakeholders, so the relevant regulations are important. This research method was carried out by taking secondary data, namely manufacturing companies listed on the Indonesian stock exchange, the number of research samples was 50 manufacturing companies, according to purposive sampling criteria during the 2016-2020 period (5 years) so that the number of samples was 250 observations. Using regression moderating, the results show that relationship loan transactions, relationship purchasing transactions, and relationship sales transactions have no effect on tax evasion. Meanwhile, institutional ownership weakens the effect of relationship loan transactions and relationship sales on tax avoidance, while the effect of relationship purchasing transactions on tax avoidance is not moderated by institutional ownership.
Stabilitas Beta Indeks JII70 di Bursa Saham Indonesia Pada Pandemi Covid-19
Authors: Togatorop Andrew Reinhard Marulak , Bahari Annisa Indira Larashati
Published: December 2022

COVID-19 pandemic attack all of Indonesia’s economic sectors, including stock market. One of the impacted were stocks that listed in JII70, which were index in Indonesia’s Stock Exchange that under the basis of sharia. To evaluate JII70 in handling pandemic, risk evaluation can be done, evaluation method that can be used is Rolling Beta. Beta show sensitivity of return that portfolio had against whole stock market performance. Rolling Beta itself is beta value that calculated in loop using Regression, in designated interval time, to make time series trend. Data were taken from JII70 and IHSG closing value, from May 2018–September 2022. Preliminary data analysis, using Augmented Dickey Fuller test show that JII70 and IHSG stationary before and during pandemic. Furthermore, beta analysis shows that JII70 has beta value at range 1,1–1,3 in 2018 before pandemic. However, after pandemic hit, JII70 beta value dropped, but can be maintained in 0,8–1,1. This showcase COVID-19 huge impact to Indonesia’s stock, including sharia stock, however, JII70 can rebound and maintain stable performance after pandemic going on.
Tax Evasion: Faktor-Faktor Yang Mempengaruhinya Menurut Persepsi Wajib Pajak
Authors: Kholis Nur , Kurniawati Lintang
Published: December 2022

that are used for national development and also the community’s economy. People’s non-compliance in carrying out their tax obligations has long been in the spotlight in Indonesia.The purpose of this study is to provide empirical evidence about the factors that influence the perception of MSME taxpayers in committing tax evasion using the variabels of Justice, Tax Sanctions, Taxation System, Disobedience Attitudes, and Discrimination Attitudes. Using 60 sample of taxpayers of Small and Medium Enterprises in Sukoharjo by sampling using random sampling of taxpayers registered at KPP Pratama Sukoharjo and using the SPSS 25 analysis tool. The results showed that the variabel of justice, tax sanctions, taxation system, taxpayer disobedience had a positive and significant effect on Tax evasion and Discrimination Attitudes had a negatif and significant effect on Tax evasion for Small and Medium Enterprises taxpayers.
Pengaruh Pengendalian Intern Terhadap Efektivitas Biaya Perjalanan Dinas
Authors: Suryani Irma , Syahrudin Muhammad , Yohanes Frans
Published: December 2022

Business travel is a cost that quite affects cash disbursements, so it is necessary to carry out effective controls to prevent fraud. The company has implemented internal control but there are still some irregularities in the management of official travel expenses. This study aims to analyze the influence of internal control on the cost effectiveness of official travel at Shafira Corporation. The research method uses quantitative research methods. Sources of data obtained from primary data with data collection through filling out a questionnaire given to 31 respondents who are employees of the company and the author’s direct observations. Data analysis used a simple regression method. The results of the study indicate that the internal control system affects the effectiveness of official travel expense where the elements of internal control have been implemented so as to minimize the risk of fraud and violations of official travel expense. The results of this study will have an impact on the cost of official travel which is carried out in accordance with budget standards and work programs that have been determined through the implementation of internal control functions.
Analisis Niat Mahasiswa Diploma III Akuntansi Menggunakan Google Classroom
Authors: Darmawan Yanto , Wiratno Dwi Haryono , Sururi Sururi , Subagyo Hasan
Published: December 2022

Google Classroom has become a popular e-learning management system in higher education during the covid-19 pandemic. However, successful implementation of Google Classroom requires acceptance by students. This study aims to explain the factors that influence accounting students’ intention to accept Google Classroom This study uses an Extended the Technology Acceptance Model to assess the acceptance and intention to use Google Classroom. Data was obtained from 326 students of Politeknik YKPN Yogyakarta through online questionnaire using Google Form. The Structural Equation Modelling – Partial Least Square approach is used to assess the measurement model and structural model. This study concludes that 1) perceived ease has no effect on students’ intention to use Google Classroom, 2) perceived of ease Google Classroom has a positive effect on perceived usefulness of Google Classroom, 3) perceived usefulness has a positive effect on students’ intention to use Google Classroom, 4) perceived behavioral control does not affect students’ intentions to use Google Classroom, and 5) subjective norms affect students’ intentions to use Google Classroom.
Identification of faults with seismic hazard potential based on morphotectonic analysis, Kerman city (Southeastern Iran)
Authors: Ameri Shahrzad , Solgi Ali , Sorbi Ali , Farrokhnia Alireza
Published: December 2022

The morphotectonic analysis is a useful time-saving and cost-effective method to assess tectonic activity, especially in large regions. In this paper, the morphotectonic study was carried out in Kerman city which is in the southeast of Iran and is a part of the Central Iran structural zone. Despite the occurrence of numerous historical and instrumental earthquakes around Kerman city, there is a gap in earthquake records of this city that has obscured its seismicity status. The aim of this study is to identify active faults and the associated seismic hazard to Kerman city. For this purpose, seven geomorphic indices namely stream length-gradient index (SL), drainage basin asymmetry (Af), hypsometric integral (Hi), ratio of valley-floor width to valley height (Vf), index of drainage basin shape (Bs), index of mountain front sinuosity (Smf) and Transverse Topographic Symmetry Factor (T) were examined for 51 basins of the study area, using digital elevation model (DEM) and geological maps in a GIS environment. Then, two kinds of relative tectonic activity index were calculated for each basin, i.e., Iat and Iat_T, from the combination of these indices. The Iat_T was chosen because its results show better agreement with the structural geology and seismic records of this region. Finally, the study area was divided into three regions according to the Iat_T values. The morphotectonic analyses indicate that the Kuhbanan fault system, especially its southern splays, has the potential to produce serious seismic hazards to Kerman city in the future; the Mahan-Jupar fault-related folds, the southern tip of the Jorjafk fault, the probable fault of Zangi-Abad, the Rafsanjan-Zarand fault system, and Gowk fault are considered as other threats to Kerman city. Furthermore, this study reveals that morphotectonic analysis is a reliable tool to evaluate fault capability and to determine the fault types, and therefore to estimate seismotectonic hazard.
Petrogenesis of the Neoproterozoic rocks of Megele area, Asosa, Western Ethiopia
Authors: Oljira Temesgen , Okunlola Olugbenga Akindeji , Olatunji Akinade Shadrach , Ayalew Dereje , Bedada Bekele Ayele
Published: December 2022

The Western Ethiopian Shield is underlain by volcano-sedimentary terranes, gneissic terranes, and ophiolitic rocks intruded by different granitoid bodies. The Megele area is part of Western Ethiopian Shield and consist of a low-grade volcano-sedimentary zone that has been intruded by mafic (dolerite dyke) and granitoid intrusions (granodiorite, diorite, granite gneiss). To establish the origin of the distinctive lithologies of the locality and evaluate its mineral potential, petrological, petrographical, and geochemical characterization of these rocks were carried out. Hence, the lithological, geochemical, and petrogenetic features of the Neoproterozoic granitoid intrusives and associated metavolcanic, were illustrated through a combination of field mapping, petrological, and geochemical analysis. The petrological result obtained from the thin section analysis of the granitoids and metabasalt from Megele area indicates that, these rocks has been metamorphosed from lower green-schist facies to lower amphibolite facies as denoted by mineral assemblages such as albite + muscovite + prehnite+ quartz and actinolite + hornblende + epidote + garnet. The major and trace element geochemical analysis of granodiorite, diorite, and granite gneiss revealed that the rocks in the studied area were mainly calc-alkaline and peraluminous in nature in the SiO2 versus Na2O+K2O and A/NK versus A/CNK, the details of the results on the major and rare elements are stated in the result section  respectively. The granitoids are S-type granites revealed silica saturated rock formed at the volcanic arc subduction (VAG) to syn-collisional (syn-COLD) tectonic setting by fractionation of LREE-enriched, HREE-depleted basaltic magma with considerable crustal input. This basaltic magma seems to be generated from the LREE-enriched, HREE-depleted mantle. In conclusion, the metabasalt is sub-alkaline (tholeiitic), metaluminous bodies generated at mid-oceanic ridge tectonic setting by partially melting of HREE-depleted and LREE-enriched basaltic magma. The magma sources are associated with the reworked sediment-laden crustal slabs from the subduction zone and resulted in S-type granitoid.
Establecimiento de biofloc a tres relaciones carbono/nitrógeno, tendiente a la producción de zooplancton
Authors: COLLAZOS LASSO LUIS , Ueno–Fukura M. , Jiménez–Moreno (Q.E.P.D.) Y. , Suárez–Contento L. , Aya–Baquero E.
Published: December 2022

El objetivo de esta investigación fue establecer el biofloc a tres relaciones carbono/ nitrógeno (C/N): 10/1, 15/1 y 20/1, determinando la secuencia de remoción de N, el perfil de sólidos y la caracterización del zooplancton, para tal fin se dispuso de tres tanques con volumen de 7000 L, incorporando oxígeno al agua a través de un aireador tipo soplador. Se utilizó como fuente de N balanceado, fuente de carbono melaza y bicarbonato de sodio como fuente alcalinizante. Al inicio se incrementó el nitrógeno amoniacal total NAT a 2 mg/L, la alcalinidad total (AT) a 120 mg/L y se adicionó como inóculo 10 litros/tanque de agua proveniente de un estanque de cultivo, al sexto y décimo días se adicionó balanceado incrementando teóricamente el NAT en 4 mg/L y a partir del día 12 en 1 mg/L. En las tres relaciones C/N se evidenciaron procesos de nitrificación durante la estabilización del biofloc, hasta llegar en el tiempo a concen­traciones no letales de amonio y nitrito para peces, menores a 1 mg/L. En cuanto a los sólidos volátiles, se encontró una mayor concentración en la relación 20/1, lo cual puede atribuirse a la mayor adición de melaza, con la consecuente producción de SSV a partir de la dominancia de comunidades heterotróficas, en los tres macrocosmos se presentaron comunidades del zooplancton, no obstante, el T2 presentaron la mayor abundancia y riqueza de organismos. Las tres relaciones C/N en biofloc establecieron condiciones de calidad de agua y alimento vivo.
new species of Andinia (Pleurothallidinae) from Peru and an updated phylogenetic analysis of the genus with emphasis on subgenus Aenigma
Authors: Ocupa-Horna Luis , Vieira-Uribe Sebastián , Ward Raven , Brose Caroline , Wilson Mark
Published: December 2022

A new species, Andinia peruviana, from Amazonas department, Peru, is described and illustrated. Updated phylogenetic analyses of nuclear internal transcribed spacer (nrITS) sequences in this study re-affirm the monophyletic nature of Andinia sensu lato and further support the previously proposed circumscription which incorporated genera Lueranthos, Masdevalliantha, Neooreophilus, and Xenosia. Andinia subgenus Aenigma was strongly supported in all analyses. The new species was determined phylogenetically to belong to subgenus Aenigma, along with A. barbata, A. dalstroemii, A. hirtzii, A. pogonion, A. schizopogon and A. uchucayensis. The phylogenetically-confirmed representatives of subgenus Aenigma are illustrated with drawings and photographs, and their geographic distribution is discussed. The updated phylogenetic analyses also show the corrected phylogenetic positions of A. vestigipetala, as the sole representative of the clade corresponding to subgenus Minuscula, and A. trimytera, as a member of the clade corresponding to subgenus Andinia.
Mediating Role of Organizational Trust in the Effect of Organizational Support Perceived By Employee on Organizational Identification: A Research in the Manufacturing Sector
Authors: KARAKULLE İsmail , AYDIN Eray , POLAT Hakkı
Published: December 2022

Organizations are institutions that have an impact on many areas of life, from the economic development of countries to the change and transformation of societies. They also have strong and continuous interaction with their environment. The rapid and different production structure brought by technology and the diversification of consumers' need for goods and services force organizations to produce more and compete with rivals. Achieving a competitive advantage and being a premier in the market are among the main goals and objectives of organizations, especially in recent years. Factors such as technology, production structure, product diversity, organizational structure, and product and service components of organizations provide significant advantages in gaining a competitive advantage. In addition to these, the most important resource that is difficult to imitate for organizations to gain a competitive advantage and that will make a difference against their competitors in terms of competence and competence is human resources. The importance given to human resources by organizations that are aware of its power is increasing day by day. In this context, the study aims to define the effect of the POS of the employees on OI and to determine the mediating role of the employees' trust in the organization in the relationship between the POS and OI. The sample of the study consists of 453 employees determined by the convenience sampling method in the production enterprises located within the organized industrial zone in Niğde and Konya provinces. The hypotheses were analyzed by the structural equation method. According to the analysis, it is seen that there is a positive and significant correlation between POS and OI (p:0,000 r:0,907), a positive and significant relationship between OI and OT (p:0,000 r:0,821), and a positive and significant correlation between POS and OT (p:0,000 r:0,779). Besides, it was defined that OT has a mediating role in the effect of POS on OI.
Disclosure Index of asset accounting procedures in the public sector
Authors: Mata Rodrigo Santos da
Published: December 2022

The objective of this study was to determine the level of disclosure of asset accounting procedures in the public sector of municipalities in the State of Espirito Santo from the perspective of analysis of the variables internal control, municipal development, population and budget revenues. Quantitative analysis methods are used in this research, such as descriptive statistics and multiple linear regression. It was found that the mean of the Disclosure of Assets Accounting Procedures Index achieved by the analyzed municipalities was 55.19%. This index suggests that the efforts made by the municipalities to meet the requirements of the regulatory agencies is still limited. The results showed that: i) the variables internal control and population were not statistically significant for the model; ii) the variables education and budget revenues showed a positive relationship with the disclosure index, indicating that municipalities with better educational levels and higher revenues tend to have higher disclosure levels. Finally, the evidence of this research contributes to the analysis of the disclosure index and its determinants, as well as to the understanding of the process of harmonization of public sector accounting to international standards in municipalities of the State of Espirito Santo.
Divriği Kompleksi’nin Taş Kenar Tonozları
Authors: ATAK Sevda
Published: December 2022

Anadolu’da Selçuklularla yaygınlaşan taş tonoz inşaatı, XIII. yüzyılın ilk çeyreğinde inşa edilen Divriği Kompleksi’nde, bütün tonoz sisteminin birbirinden farklı olduğu tek yapı olarak karşımıza çıkar. Türkiye Selçuklu mimarisi, kenar sayılarının yüzeyde oluşturdukları çıkıntılı kenarlar ve girintili açılara göre sınıflandırılabilir, olağanüstü ve çok sayıda tonoz çeşitliliğine sahiptir. Divriği Kompleksi ise bu bağlamda, Anadolu’da bilinen en erken tarihli örnekleri temsil etmektedir. Burada, araştırmanın hedefi olarak, Divriği Kompleksi kenar tonozlarını bir dizi şeklinde sunarak, geometrik yapıları üzerinde durulmuştur. Dahası kendinden önce ve sonraki Anadolu Selçuklu eserleri içerisinde de sahip olduğu kenar tonozlar bakımından da bir değerlendirme yapılmıştır. Bunun sonucunda daha erken tarihli yalnız tuğla tonoz örneklerine rastlanır iken, kendinden sonraki yıllarda ise benzer taş tonoz örnekleri mevcut olduğu görülmüştür. Böylelikle de kendi dönemi içerisindeki kesme taş tonoz inşaatına ışık tutmuş ve yayılmasına öncülük etmiş olmalıdır. Bulunduğu coğrafyanın XIII. yüzyıl mimarisi içinde eser, sahip olduğu kenar tonozların inşasında benimsenen çözüm çeşitliliğine dikkat çekerek yeniden değerlendirilmiştir.
Ordu Şehrinin Kuruluşuna Öncülük Eden Vakıf Eserlerinden Eskipazar (Hacı Emir İbrahim Bey) Camisi
Authors: İLTAR Gazanfer , FATSA Mehmet
Published: December 2022

Eskipazar Camisi, Ordu şehir merkezinin 4 km güneyinde, Ulubey Yolu üzerindeki eski şehir kalıntıları arasındaki ayakta kalabilen en büyük yapıdır. Hacıemiroğulları Beyliği döneminde Emir İbrahim Bey tarafından 1380’li yıllarda yaptırılmıştır. Beylik döneminde ordugâh camisi, Osmanlı idaresine geçtikten sonra ise Canik-i Bayramlu Vilayeti’nin merkez camisi olarak kullanılmıştır. Bu özelliği ile Ordu şehrinin de kuruluşuna öncülük etmiş, ismine ilham kaynağı olmuştur. 17. ve 18. Yüzyıllarda yaşanan isyanlarda zarar gördüğü için kapsamlı onarımlardan geçirilmiştir. 1939 Erzincan Depremi’nde yıkıldıktan sonra, 1946 yılında başlayan restorasyonla bugünkü şeklini almıştır. Etrafında yaşanan olayların ve geçirdiği aşamaların izlerini taşıması bakımından anı değeri yüksek bir kültür varlığı olarak kabul edilir. Bu çalışma, söz konusu cami ile müştemilatının tarihi aşamalarını ve mimari özelliklerini incelemektedir.
NATIONAL DEVELOPMENT GOALS OF RUSSIA AT THE REGIONAL LEVEL: POLITICAL AND GEOGRAPHICAL ANALYSIS
Authors:   V. B. Sochava Institute of Geography of the Siberian Branch of the Russian Academy of Sciences, Blanutsa V. I.
Published: December 2022

The study groups the regions of Russia by the multidimensional distance to the national development goals determining the preference ratio of the identified groups according to possible political consequences for the heads of regions. The initial data for 85 regions and 15 indicators for 2021–2030 are taken from the appendix to the «Unified Plan for Achieving the National Development Goals of the Russian Federation for the Period up to 2024 and for the Planning Period up to 2030». The research uses methods of grouping regions, comparative analysis, and assessment of spatial autocorrelation and regions' economic-geographical location. Four groups of regions have been identified by the multidimensional distance to hypothetical regions, each of which corresponds to a certain quartile of a ranked series of relative increases in the values of target indicators. The resulting grouping of regions is interpreted according to the length of the path to national development goals and the likelihood of a change of regional government due to the non-fulfillment of the goals. Additional potential threats to senior officials of the Russian Federation’s subjects are determined by the spatial autocorrelation of the regions and their position in relation to the regions of the first and fourth groups.
FOREIGN POLICY EXPERTISE: THE RESEARCH POTENTIAL OF CRITICAL GEOPOLITICS
Authors:   Donetsk National University, Onopko O. V.
Published: December 2022

The author determines the possibilities of using the theoretical and methodological apparatus of critical geopolitics to study foreign policy expertise. Accordingly, the key views of scientists specializing in the field of critical geopolitics on the problems of foreign policy expertise were summarized and systematized; the concept of critical geopolitics by G. O'Tuathail was expanded and supplemented; the significance of foreign policy expertise at various levels of geopolitical discourse was analyzed; the author's definition was proposed and the features of expert geopolitical discourse were established, its types determined. Consequently, it was substantiated that foreign policy expertise may be a network-organized set of actors in geopolitical discourse. By virtue of their expert status, they have the ability to decisively influence the geopolitical ideas of the population and political actors, alongside the process of the political decision-making process in the field of foreign policy, defense and security. The study determined that the subjects of foreign policy expertise act at all major levels of geopolitical discourse, forming its separate direction – expert geopolitical discourse. Within its framework, they form both ideological and theoretical, conceptual, as well as applied and popular geopolitical ideas that make up the geopolitical pictures of the world of ordinary citizens and the political elite.
Reforming European Union Conflict Policy in the Context of the Crisis in Ukraine
Authors:   Primakov National Research Institute of World Economy and International Relations, Russian Academy  of Science, Ofitserov-Belskiy Dmitriy V.
Published: December 2022

Introduction: in 2020 the European Union (EU) reviewed its key documents designed as guidelines for peacekeeping practices; this was aimed at broadening the geography of participation, ensuring more efficient interaction between government and non-governmental structures, as well as providing more flexibility in dealing with parties of conflict zones. For the past three decades, the EU’s peacekeeping activities have changed drastically, turning mainly into a factor of European “soft power” and influence expansion. Objectives: to consider transformations in peacekeeping processes at the US regulatory and institutional levels. Methods: analysis of the EU regulatory and contractual framework, conceptual documents. Results: the article covers the motives for EU participation in peace mediation and the leading theories explaining them. The author concluded that before the escalation of the conflict in Ukraine in 2022, the restrictions that prevented the EU involvement in the conflict played a greater role than the motives for participation. However, due to the confrontation between Russia and the West, the aspect of peacekeeping policy that was associated with unwillingness to collide with Russian interests and always weakened it, has generally lost its relevance. Conclusions: recent transformations in peacekeeping processes at US regulatory and institutional levels expand the EU’s reaction capability; but upscaling these activities and increasing its efficiency do not seem possible without a fundamental review of the Common Foreign and Security Policy instruments.
La confianza en el siglo XXI: conceptos, estrategias y prácticas
Authors:   Universidad EAFIT, Cano Carolina , Díaz Pérez Simón ,   Universidad EAFIT, Fortou Jose Antonio ,   Universidad EAFIT, Giraldo Ramírez Jorge , Ramírez Manuela ,   Universidad EAFIT, Restrepo Julia ,   Universidad EAFIT, Reyes Sarmiento Martha ,   Universidad EAFIT, Rivas Montoya Luz María ,   Universidad EAFIT, Rodríguez-García Giovanna ,   Universidad Nacional Autónoma de México (UNAM), Silva Santiago ,   Universidad EAFIT, Suárez José Luis ,   Western Ontario University
Published: December 2022

Podría decirse que un signo de nuestros tiempos es el deterioro de la confianza. No es de extrañar que las preguntas sobre ella partan de la necesidad de acotar bien el concepto y también que aparezca la dificultad para encontrar formas satisfactorias de resolver el problema práctico de cómo construirla o recuperarla. Este libro es el punto de encuentro de varias trayectorias investigativas, unas en la Universidad EAFIT, en materia de valores, capital social y estrategia, y otras en Western Ontario University, en análisis digital. Estas búsquedas convergieron en proyectos materializados entre 2018 y 2021, a la luz de conversaciones y trabajos conjuntos con empresas colombianas y canadienses. La amplia revisión de literatura que se efectuó nos permite afirmar que en el contexto hispanoamericano el tema de la confianza no parece haber llamado con fuerza la atención de la academia; al menos no con la atención y la dedicación que tiene en el ámbito anglosajón.
Estratégias para prevenir condições geradoras de riscos relacionados à administração medicamentosa: uma revisão de escopo
Authors: Camerini Flavia Giron , Silva Thays Geovana Pacheco da , Henrique Danielle de Mendonça , Gonçalves Camilla Garcia de França , Costa Beatriz Diniz dos Santos , Fassarella Cintia Silva
Published: December 2022

OBJETIVO: Mapear na literatura estratégias de segurança para prevenir condições geradoras de riscos relacionados à administração de medicamentos intravenosos em pacientes críticos. MÉTODOS E MATERIAIS: Trata-se de uma revisão de escopo, seguindo a metodologia do Joanna Briggs Institute (JBI), de estudos publicados entre 2012 e 2021, sem limitação de idioma ou desenho de estudo, com busca nas bases de dados online SciELO, Medline/PubMed, LILACS, BVS e BDENF. RESULTADOS: Foram encontrados 261 registros, dos quais 11 foram incluídos nesta revisão, identificando 8 estratégias para prevenção de condições geradoras de riscos durante a administração intravenosa de medicamentos. CONCLUSÃO: Foram elencadas estratégias possiveis de serem implementadas na prática, possibilitando a mitigação de erros na administração intravenosa de medicamentos e aumentando a segurança na terapia infusional em unidades intensivas.
Use of a FlowCam for descriptive measurements of Aureococcus anophagefferens live culture cells v1
Authors: E. Chase Emily
Published: December 2022

A protocol for acquiring an array of descriptive statistics (e.g., cell count, cell diameter, cell volume) for a monoculture of Aureococcus anophagefferens. This procedure permits an in-depth profile of your cultures via a substantial number of viewable photos and measurements. We recommend this familiarity with your study cells, especially when applying stress treatments such as virus infection, light cycle changes, etc.
In Silico analysis links the NSL complex to Parkinson’s disease and the mitochondria – Protein-protein interaction data to functional enrichment analysis v1
Authors: Kelly Katie
Published: December 2022

Whilst the majority (~90-95%) of PD cases are sporadic, much of our understanding of the pathophysiological basis of disease can be traced back to the study of rare, monogenic forms of disease. However, in the past decade, the availability of Genome-Wide Association Studies (GWAS) has facilitated a shift in focus, toward identifying common risk variants conferring an increased risk of developing PD across the population. A recently developed mitophagy screening assay of GWAS candidates, has functionally implicated the non-specific lethal (NSL) complex, a chromatin remodeler, in the regulation of PINK1-mitophagy. Here, a bioinformatics approach has been taken to investigate the interactome of the NSL complex, to unpick its relevance to PD progression. The mitochondrial interactome of the NSL complex has been built, mining 3 separate repositories: PINOT, HIPPIE and MIST, for curated, literature-derived protein-protein interaction (PPI) data. A multi-layered approach has been taken to; i) build the ‘mitochondrial’ NSL interactome, applying PD gene-set enrichment analysis to explore the relevance of the NSL mitochondrial interactome to PD and, ii) build the PD-oriented NSL interactome, using functional enrichment, to uncover biological pathways underpinning the NSL /PD association.
CTAB-based DNA extraction for citrus v1
Authors: Goto Shingo
Published: December 2022

CTAB-based protocols are used for genomic DNA extraction from many kinds of plant species. However, the protocols can’t necessarily completely remove contamination of polysaccharide and RNA in extracted genomic DNA solution. Especially, citrus leaves generally contain high polysaccharide. This protocol is a simple and efficient method for extracting genomic DNA for citrus without contamination of polysaccharide and RNA.
Quantify photophysiology of endosymbiotic dinoflagellates (Symbiodiniaceae) using the Guava Flow Cytometer v1
Authors: J Anthony Colin
Published: December 2022

This protocol quantifies light-harvesting complex (LHC) and antioxidant pigments, while simultaneously determining cell density of endosymbiotic dinoflagellates using the Guava Flow Cytometer. Red fluorescence excited by a blue laser represents peridinin, while the red fluorescence excited by the red laser represents both chlorophyll a and chlorophyll c2 , providing insight into Symbiodiniaceae LHC prioritization. Additionally, green fluorescence off of the blue excitation laser target antioxidant-associated pigments (diadinoxanthin, diatoxanthin, beta-carotene, and flavin-based fluorescent proteins). As flow cytometry continues to gain traction as a robust cell counting methodology, the integration and expansion of this protocol into coral or micro-algal workflows will serve as a valuable tool to quantify the physiology of single photosymbiotic cells in-hospite.
Business Model Canvas für die Promotion
Authors: Hoffmann Martin W. , Drath Rainer , Hildebrandt Gary
Published: December 2022

Eine Promotion stellt Doktoranden vor große organisatorische und kommunikative Herausforderungen und ihre Betreuer möchten sie zielführend begleiten. Gerade im Ingenieursumfeld stellt eine Promotion junge Menschen vor große Anforderungen an die Fähigkeit, komplexe Sachverhalte verständlich und überzeugend zu kommunizieren. In diesem Beitrag wird das Business-Model-Canvas untersucht, um die verschiedenen Phasen einer Promotion genau in diesem wunden Punkt effizient zu unterstützen. Dazu wird das Business-Model-Canvas, eine in der industriellen Praxis bewährte Methodik, auf die Problemwelt der Promotion übertragen. Zielstellung ist, die interne und externe Kommunikation und den  Wissenstransfer deutlich zu verbessern. Daraus leiten die Autoren hilfreiche Empfehlungen für Doktoranden und ihre Betreuer ab und erläutern, wie diese die Promotionszeit erleichtern.
Az okosváros-tervezés fejlődéstörténete kritikai megközelítésben
Authors: Gere László , Kocsis János Balázs
Published: December 2022

A városfejlesztés egyik legújabb paradigmája, az úgynevezett okosváros-tervezés is immár közel két évtizedes múltra tekint vissza, ezért lehetőség nyílt a folyamat egyfajta fejlődéstörténetének, „evolúciójának” megrajzolására. Bár igen rövid időszakról van szó, mégis figyelemre méltó párhuzamokat azonosíthatunk a várostervezés egészének folyamatával a 20. század második felétől kezdve. Cikkünk ebből a megközelítésből kiindulva mutatja be az okosváros-tervezés három szakaszát a nemzetközi szakirodalomban kibontakozó diskurzus elemzésével. Először számba veszi a fogalommeghatározása körül kialakult különbségeket, kérdéseket és dilemmákat. Ezt követően részletesen vizsgálja az említett három szakaszt (a megjelenés évei; kritikák megfogalmazása, mint második szakasz; majd megújulás és ismételt felívelés) a domináns szakmai párbeszéd elemzése révén. Az eredmények azt mutatják, hogy bár éles határvonalakat nem lehet húzni, és számos téma a kezdetektől „átível” a folyamaton, egyfajta hangsúlyeltolódás mégis azonosítható. Ezt a szakaszolást pedig rá lehet vetíteni a 20. század második felétől jellemző városfejlesztési folyamatokra általában és egyfajta párhuzamként egyaránt.
A tanulmány további része az elméleti elemzést egy, a témához kapcsolódó hazai kutatás eredményeinek bemutatásával is igyekszik megvilágítani, melynek témája az okosváros-eszközök, a helyi fejlesztés és a helyi közösség viszonyrendszerének vizsgálata volt. Ennek legfőbb tanulsága szerint a legkisebb településekre általában túlzott terhet ró mind az anyagi, mind az emberi erőforrások oldalán az infokommunikációs eszközök működtetése, és hasznát is kevéssé látják, míg a nagyobbaknál erre nagyobb szükség és igény is van. Főképpen a kisebb lélekszámú településeken hiányzik az ehhez szükséges technológiai, szervezeti és menedzsment háttér és -kapacitás, és jelentős idegenkedés is tapasztalható e települési körben.
Kohéziós források felhasználásának területi vizsgálata Baranya megyében a 2007-2013-as és 2014-2020-as programozási időszakban
Authors: Pámer Zoltán
Published: December 2022

A 2007-2013 közötti programozási időszak a területalapú fejlesztéspolitika kialakítására tett kísérletként értelmezhető, melynek során – az ágazati programok mellett – minden magyarországi régió (így a Baranyát magában foglaló Dél-Dunántúl is) saját operatív programmal rendelkezett. 2014-2020 között ugyanakkor egyetlen országos, viszont különálló megyei keretekkel rendelkező Terület- és Településfejlesztési Operatív Program működött, melyet szintén kiegészítettek az ágazati programok. A tanulmány célja, hogy feltárja: kimutathatók-e tendenciák Baranyában a támogatási programok területi preferenciáiban, továbbá mely járások és települések tekinthetők centrumnak vagy perifériának az EU-források felhasználása terén a két programozási időszakban. A tanulmány első részében – a szakirodalmi bevezetést követően – áttekintem a két programozási időszak stratégiai kereteit, a Baranya megyében vizsgált programokat, illetve a megyére vonatkozó területi célokat. Ezt követően ismertetem az empirikus adatelemzés módszerét és a megfogalmazott kérdéseket, majd bemutatom a két időszak programjait külön-külön, továbbá összehasonlítom a két területfejlesztési célú programot. Kiemelem a két programozási időszakra jellemző területi tendenciákat, továbbá értékelem a forrásfelhasználást a 2014-ben kialakított megyei területi célok mentén. Az összefoglalásban a korábbi elemzések konklúziójaként meghatározom a megye járásainak kohéziós forrásfelhasználási profilját.
A tanulmány fontos megállapítása, hogy a megyeszékhely, Pécs részesedése a forrásokból 50% alá süllyedt 2014-2020 között, mely a vidéki térségek előtérbe kerülésére utal. Azonban míg 2007-2013 időszakában mind az egyes járások között, mind a járásokon belül viszonylag egyenletes forrásmegoszlás tapasztalható, addig 2014-2020 között több járás (Bóly, Komló, Mohács) esetében is erőteljes koncentrációt látunk (ezek elsősorban helyi adottságokra épülő gazdaságfejlesztést megvalósító térségek), miközben a leszakadó térségeknek kevesebb támogatás jutott. A preferált járásokon belül is a központok koncentrálták a forrásokat. Mindez összességében növelte a megye elmaradott és fejlődő térségei közötti finanszírozási szakadékot. Az uniós fejlesztéspolitika központi térségekre és városokra történő koncentrálásával csökken annak láthatósága a vidéki térségekben, mely – utóbbi területeken – a hazai finanszírozású eszközök jelentőségének növekedésével jár.
Multi-Resolution Grids in Earthquake Forecasting: The Quadtree Approach
Authors: Asim Khawaja M. , Schorlemmer Danijel , Hainzl Sebastian , Iturrieta Pablo , Savran William H. , Bayona José A. , Werner Maximilian J.
Published: December 2022

The Collaboratory for the Study of Earthquake Predictability (CSEP) is an international effort to evaluate probabilistic earthquake forecasting models. CSEP provides the cyberinfrastructure and testing methods needed to evaluate earthquake forecasts. The most common way to represent a probabilistic earthquake forecast involves specifying the average rate of earthquakes within discrete spatial cells, subdivided into magnitude bins. Typically, the spatial component uses a single-resolution Cartesian grid with spatial cell dimensions of 0.1° × 0.1° in latitude and longitude, leading to 6.48 million spatial cells for the global testing region. However, the quantity of data (e.g., number of earthquakes) available to generate and test a forecast model is usually several orders of magnitude less than the millions of spatial cells, leading to a huge disparity in the number of earthquakes and the number of cells in the grid. In this study, we propose the Quadtree to create multi-resolution grid, locally adjusted mirroring the available data for forecast generation and testing, thus providing a data-driven resolution of forecasts. The Quadtree is a hierarchical tree-based data structure used in combination with the Mercator projection to generate spatial grids. It is easy to implement and has numerous scientific and technological applications. To facilitate its application to end users, we integrated codes handling Quadtrees into pyCSEP, an open-source Python package containing tools for evaluating earthquake forecasts. Using a sample model, we demonstrate how forecast model generation can be improved significantly in terms of information gain if constrained on a multi-resolution grid instead of a high-resolution uniform grid. In addition, we demonstrate that multi-resolution Quadtree grids lead to reduced computational costs. Thus, we anitcipate that Quadtree grids will be useful for developing and evaluating earthquake forecasts.
Ublituximab: A Novel Anti-CD20 Therapy for Multiple Sclerosis
Authors: Wolf Andrew B ,   Department of Neurology and Rocky Mountain Multiple Sclerosis Center, University of Colorado School of Medicine, Aurora, CO, USA, Alvarez Enrique ,   Department of Neurology and Rocky Mountain Multiple Sclerosis Center, University of Colorado School of Medicine, Aurora, CO, USA
Published: December 2022

Ublituximab is a novel anti-CD20 therapy developed for the treatment of patients with multiple sclerosis. It is a glycoengineered chimeric antibody with a novel epitope on CD20, with high antibody-dependent cell-mediated cytotoxicity. Maintenance doses are administered every 6 months over an hour, providing a convenient dosing regimen. The identical phase III randomized, double-blind, active comparator to teriflunomide trials ULTIMATE I and II were completed in early 2022. ULTIMATE I and II, respectively, demonstrated that ublituximab had a strong clinical effect, with annualized relapse rates of 0.08 and 0.09 or reductions of 59% and 49% over teriflunomide. In addition, in ULTIMATE I and II, radiographic efficacy similarly reduced contrast-enhancing lesions by 97% and 96% and new/enlarging T2 lesions by 92% and 90%, respectively. Although ublituximab did not decrease confirmed disability progression in a pooled analysis of both studies, there was an increase in the confirmed disability improvement. Ublituximab was well tolerated, including infusion reactions that were predominantly mild and only seen with the first infusion. Further long-term safety data, as well as relative efficacy compared with current anti-CD20 therapies, will need to be evaluated in the real-world setting if ublituximab is to be approved as expected in December 2022.