bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Influence of Market Dynamics on Supply Chain Sustainability in the Renewable Energy Sector
Authors: Reynolds Samantha
Published: May 2024

This qualitative research investigates the intricate relationship between market dynamics and supply chain sustainability in the renewable energy sector. Amidst the global energy transition, renewable energy has emerged as a crucial player in mitigating climate change and fostering sustainable development. However, ensuring the sustainability of renewable energy supply chains presents complex challenges shaped by various market forces. Through semi-structured interviews and thematic analysis, this study explores how policy frameworks, technological innovation, market competition, consumer preferences, and investor demands influence sustainability practices across the renewable energy supply chain. The findings highlight the critical role of supportive policy environments, technological advancements, and stakeholder collaboration in driving sustainability performance and mitigating risks within renewable energy supply chains. Furthermore, the study identifies challenges such as supply chain complexity, regulatory compliance, and stakeholder engagement, underscoring the need for collaborative efforts and multi-stakeholder partnerships. By addressing these challenges and leveraging opportunities, stakeholders can advance sustainability goals, mitigate climate change impacts, and foster a more resilient and equitable renewable energy sector. The research contributes to a deeper understanding of market dynamics and supply chain sustainability in the renewable energy sector, offering insights for policymakers, industry stakeholders, and sustainability practitioners to inform evidence-based decision-making and drive positive change.
Constituição da identidade docente de bacharéis em Engenharia: narrativas do habitar à docência na universidade
Authors: Silva Fabrício Oliveira da , Gagliato Jéferson Felipe
Published: May 2024

Este estudo aborda a Constituição da identidade docente de bacharéis em Engenharia: narrativas do habitar à docência na Universidade. O principal objetivo do estudo foi compreender o processo de constituição da identidade de professores bacharéis em Engenharia na Universidade Estadual de Feira de Santana-UEFS, Bahia. A metodologia desta pesquisa é de natureza qualitativa, e ancora-se na abordagem (auto)biográfica. Como método de coleta de informações, utilizou-se entrevistas narrativas, que foram gravadas, transcritas e analisadas à luz do paradigma compreensivo e interpretativo de Ricouer (2012) e Souza (2014). A pesquisa contou com a colaboração de quatro docentes universitários dos cursos de engenharias (Civil, Alimentos e Computação) da UEFS. No campo teórico, a pesquisa embasa-se a partir das contribuições teóricas, que tematizam conceitos como identidade docente, experiência, profissão docente, formação permanente, entre outros. Os resultados permitem concluir que as identidades profissionais são constituídas pela trajetória de atuação profissional. As narrativas evidenciaram processos de subjetivações que cada professor produz ao narrar acerca da sua própria atuação na docência universitária, transversalizada pelas experiências familiares. O estudo permitiu, ainda, concluir que as identidades são flexíveis, e constituem-se a partir das experiências que cada docente constrói na travessia profissional.
Relationship Between Multimorbidity, Nutritional Status and Duration of ARV Treatment to Major Signs of HIV at RSUD Dr. Soetomo Surabaya
Authors: Alifia Kartika , Wardani Hartati Eko , Tama Tika Dwi , Hapsari Anindya , Gayatri Rara Warih
Published: May 2024

People living with HIV/AIDS (PLWHA) can have better health outcomes with early identification of the AIDS phase. In the first three years, PLWHA may progress to the AIDS stage. This cross-sectional study aimed to determine the relationship between multimorbidity, nutritional status and duration of Antiretroviral (ARV) treatment on major signs of PLWHA. This study was conducted in the Intermediate and Infectious Disease Treatment Unit (UPIPI) at regional public hospital (RSUD) Dr. Soetomo Surabaya from January to February 2023. As many as 52 PLWHA who started HIV treatment at RSUD Dr. Soetomo in 2020 to 2021 were sampled in this study, which was obtained from medical records. The dependent variable in this study was the major sign of HIV. Independent variables in this study were multimorbidity, nutritional status, and the duration of ARV treatment. This study found that 76.9% of PLWHA experienced major signs. Multimorbidity and duration of ARV treatment did not have an association with major signs of HIV (p-value > 0.05). Nutritional status has a significant association with major clinical symptoms of HIV (p-value < 0.05). PLWHA with underweight had higher odds of having a major sign (p-value = 0.017; PR = 1.507; 95% CI 1.131-2.008) than PLWHA with normal nutritional status. Thereby, it is hoped that the hospital will be assisted in determining health promotion needs such as screening and evaluation of nutritional status to monitor the nutritional status of patients, which will improve their health outcomes.
Assessment of Land Quality for Siamese Orange (Citrus nobilis var. microcarpa) Development in Pacitan Regency, Indonesia
Authors: Rahayu Rahayu , Supriyadi Supriyadi , Sumani Sumani , Herawati Aktavia , Dewi Kurnia Mukti , Mo Yang Geun , Bae Eun Ji
Published: May 2024

Siamese oranges are one of the most widely developed horticultural crops in Indonesia. Arjosari and Ngadirojo are some of the sub-districts that produce Siamese orange in Pacitan Regency. One of the factors that can affect the development of citrus is land quality. This study aims to obtain land quality index data and improvement efforts for developing Siamese orange. Soil samples were taken from 25 land mapping units (LMUs) with 87 sample points. The soil sampling points were determined based on area or sampling density. Data analysis used for soil quality assessment includes correlation, principal component analysis (PCA), minimum data set (MDS), and calculation of climate quality index. The parameters used in this study are bulk density, porosity, moisture content, texture, pH, electrical conductivity (EC), cation exchange capacity (CEC), base saturation, total N, available P, available K, soil organic carbon (SOC), microbial biomass carbon (MBC), evapotranspiration, temperature, and solar radiation. Based on the results of soil quality analysis in the study area, it has a value range of 0.28 to 0.37, including low class, while the climate quality index is 1.39 with moderate class. The land quality index has a very low to low class with a value of 0.39 to 0.51. Intrinsic, extrinsic, and anthropogenic factors can influence soil quality. The study area’s limiting factors for developing Siamese oranges are EC, total N, and available P, which can be improved by making furrow ponds, adding organic fertilizer, using urea fertilizer, and SP36 according to the dosage.
Modification of Media Formulation and Agar Concentration to Improve Pitcher Plant (Nepenthes mirabilis (Lour.) Druce) Micropropagation for Conservation and Microfloriculture Development
Authors: Putri Andes Khofifah , Prasetyo Rendie , Proklamasiningsih Elly , Davison Paul A. , Sugiyono Sugiyono
Published: May 2024

The pitcher plant (Nepenthes mirabilis (Lour.) Druce) is a unique plant listed in the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) Appendix II and is protected in Indonesia. Conventional propagation of N. mirabilis is difficult and takes a longer time. Therefore, in vitro culture method is proposed. This study aimed to determine the best and most economical media formulation and agar concentration for N. mirabilis micropropagation. This research has been carried out experimentally using a completely randomized two-factor factorial design. The first factor was the media formulation (full-strength Murashige and Skoog (MS), half-strength MS, half-strength MS + AB mix, and AB mix) and the second factor was agar concentrations (6, 8, and 10 g l-1). Twelve treatment combinations were obtained and repeated 5 times to produce 60 experimental units. The explants were apical microshoots (1.5 cm long with 5 leaflets). The cultures were incubated at 24 ℃ under continuous light for 16 weeks. The parameters measured included shoot emergence time, number of shoots, number of leaves, and shoot length. The data were analyzed using variance analysis followed by Duncan’s multiple range test at a 95% confidence level. The results showed that half-strength MS medium resulted in the highest number of shoots and leaves and the longest shoot length, whereas adding 8 g l-1 agar resulted in the fastest shoot emergence time. Half-strength MS medium solidified with 8 g l-1 agar could produce many N. mirabilis (Lour.) Druce microshoots to support both conservation and microfloriculture development.
The Impact of Social Media Marketing, E-Service Quality, and Review Content on Online Purchase Intention Analyzing the Role of Trust in Grab
Authors: Kaneshia Achmadi  , Novitasar Syadela , Usman Osly
Published: May 2024

In the We Are Social 2020-Digital 2020 Indonesia report as of January 2020, it was revealed that more than 21.7 million people in Indonesia had adopted ride-hailing or ride-sharing services, including the use of the Grab application. In this context, this research aims to examine the factors that influence the trust of Grab application users, by analyzing the influence of Social Media Marketing, E-Service Quality, and Content Reviews on Online Purchase Intentions. The purpose of this research is to explain the relationship between Social Media Marketing (X1), E-service Quality (X2), and Review Content (X3) with Purchase Intention(Y1) in the context of using the Grab application, as well as how Purchase Intention acts as a mediator in this relationship. Additionally, this research will explore how Trust Level (Z1) is influenced by Purchase Intention and other factors in the Grab ecosystem. This research uses quantitative research and a descriptive approach to determine each variable. Empirical results highlight that social media marketing and e-service quality have an influence on purchase intention. However, content reviews do not have a significant influence on purchase intentions, and social media marketing variables, electronic service quality, and content reviews through trust variables do not have an influence on purchase intentions.
The Influence Of Information Technology And Tax Awareness On Interest In Participating Tax Amnesty
Authors: Sari Yessi Avita , Noviarita Heni , Anggraeni Erike
Published: May 2024

The country's biggest source of income is taxes. Taxes have a dominant role in developing the country both in terms of infrastructure and alleviating poverty and community needs in terms of health, education and social security for those in need. Efforts to increase tax revenues can be implemented optimally and require supporting methods, including extensification and intensification. Apart from that, technology and information are needed to create awareness of non-compliant taxation so that it can increase compliance interest in participating in the tax amnesty. The aim of this research is to examine the tax stimulus in the technological sphere regarding awareness of interest in following the tax amnesty policy. The research method used is qualitative research with a Literature Review approach model examining previous research for the 2017-2022 period, totaling 40 journals. The aim of the research is to determine the effect of internet technology in increasing awareness of participating in the tax amnesty program. The results prove that technology and information have a positive effect in increasing taxpayer awareness of the tax amnesty program because in the midst of the digitalization era, it is necessary for all humans to switch to manual access to changes in technology and information.
Reinvigorating Unicorn Startup Employee Productivity Following Mass Layoffs
Authors: Rachma Dania Rizki Firdausi , Gulabdin Shaierah
Published: May 2024

The transition period from the pandemic back to normal and the global recession triggered many employee layoffs, especially in unicorn startup companies. This mass layoff also had an impact on the remaining employees. This research wants to analyze how to maintain the performance of remaining employees when viewed from the influence of work stress, communication and job satisfaction. The sample is company employees in Jakarta, and the sample size is 200 people. The Jakarta location was chosen because most unicorn startup companies are in this city. The research sample was selected using a purposive sampling technique. The quantitative data processing method is carried out using the survey method. The data is processed using the Lisrel application.
Unicorn startup employee, Employee Perfomance, Job satisfaction, Work stress, Communication
Analysis of Factors That Influence Brand Awareness and Purchasing Decisions on Online Marketplace
Authors: Khairunisa Nadya Addinary , Kalila Sekar Ayu , Usman Osly
Published: May 2024

The expansion of digital technology and internet users in Indonesia parallels the expansion of marketplaces where consumers may purchase online. In recent years, Shopee, a marketplace app that offers a variety of products and services, has grown tremendously. However, in an increasingly competitive industry, Understanding the elements that drive brand awareness and consumer purchase decisions is critical. The study collected and analyzed data using quantitative research techniques. Data from the survey were analyzed using statistical software SEM PLS using the help of smart pls 4.0. Brand ambassador, brand personality, and price is substantial and has a positive impact on brand awareness and purchasing decisions. As Shopee at the top-of-mind level of consumers, it makes them continue to keep consumers in their minds and will continue to use Shopee to make product purchases.
Fun and E-learning (A Hybrid Teaching Factory Model)
Authors: Nurmalasari Dewi , Yulia Astri , Rusni Izyani Mat
Published: May 2024

Educators must possess the capacity to create engaging instructional sessions that are tailored to specific time periods and generational attributes. This study explores the concept of an engaging educational setting within the context of the generation Z period. Furthermore, technological advancements have offered individuals supplementary prospects to cultivate and nurture social connections in what is commonly referred to as e-learning. Classroom management encompasses the coordination of classroom activities to enhance learning, along with the teacher's proficiency in creating an optimal learning environment through the use of technology, in line with the demands of the digital era, to address any challenges that arise during the learning process. The primary objectives of utilizing (digital) technology in classroom management are to enhance the learning quality and maximize the overall learning experience (e-learning). Attaining educational objectives is essential for guaranteeing the excellence of the learning process. Classroom management abilities encompass educators' capacity to effectively establish and sustain an ideal educational setting by adeptly employing technology in accordance with contemporary trends and the distinctive learning attributes of Generation Z students. Efficiently managing the teaching and learning process requires a systematic approach that encompasses tasks such as planning, organizing, controlling, and supervision. These actions are conducted concurrently, thoroughly, and in an integrated manner. A learning approach using technology carried out in a hybrid according to the teaching factory concept is a good solution for achieving learning objectives.
Humeral Component Version Has No Effect on Outcomes Following Reverse Total Shoulder Arthroplasty
Authors: Wiater J. Michael , Lee James Y.J. , Shields Edward J.W. , Childers Karen , Dery Lauren , Koueiter Denise
Published: May 2024

Background:

Controversy exists regarding the ideal humeral component version to optimize humeral rotation and patient outcomes in reverse total shoulder arthroplasty (rTSA).

Methods:

Patients undergoing primary rTSA for rotator cuff tear arthropathy, a massive rotator cuff tear, or primary osteoarthritis with a rotator cuff tear were randomized to placement of the humeral component in neutral version or 30° of retroversion. Shoulder active range of motion and strength and visual analog scale (VAS) pain, American Shoulder and Elbow Surgeons (ASES), and Patient-Reported Outcomes Measurement Information System Global 10 (PROMIS-10) scores were collected up to 2 years postoperatively. The goal of the study was to determine whether humeral external rotation and internal rotation are affected by humeral component version following rTSA at 2 years postoperatively.

Results:

Sixty-six patients were included in the analysis. The median follow-up was 26 months for the neutral and 27 months for the 30° retroversion group. No differences between the groups were observed with respect to the primary diagnosis, sex, age, body mass index, or American Society of Anesthesiologists (ASA) class. The 2 groups did not differ significantly in terms of improvement at 2 years in active shoulder abduction (p = 0.969), forward elevation (p = 1.000), internal rotation measured as the highest spinal level reached (p = 1.000), internal rotation with the arm abducted 90° (p = 0.451), external rotation (p = 0.362), or muscle strength in forward elevation (p = 1.000), abduction (p = 1.000), external rotation (p = 0.617), or internal rotation (p = 1.000). The 2 groups did not differ significantly in terms of improvement in postoperative ASES (p = 1.000), PROMIS-10 physical (p = 1.000), or VAS pain scores (p = 0.718) at the time of final follow-up. In the neutral version group, 1 patient underwent revision for instability and 1 for stiffness. One acromial stress fracture occurred in the 30° humeral retroversion group. Scapular notching was observed in 7 (21.2%) of the patients in neutral version group and 5 (15.2%) of the patients in the 30° retroversion group (p = 0.750).

Conclusions:

Securing the humeral component at neutral version or 30° of retroversion in rTSA resulted in similar active shoulder external rotation, internal rotation, forward elevation, abduction, and strength measurements, complication rates, and VAS pain, PROMIS-10 physical, and ASES scores at 2 years postoperatively.

Level of Evidence:

Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Transiliac-Shortening Osteotomy to Treat Ischial Pressure Injury due to Fixed Pelvic Obliquity
Authors: Schwend Richard M. , Nguyen Brandon T. , Noe McKenna C. , Anderson John T. , Jiang Shao
Published: May 2024

Case:

A 17-year-old adolescent boy with Gross Motor Function Classification System 5 cerebral palsy and neuromuscular scoliosis underwent posterior spinal fusion and segmental spinal instrumentation from T3 to the pelvis. He developed a right ischial pressure injury a few months postoperatively, which persisted despite nonoperative measures. He subsequently underwent an ipsilateral transiliac-shortening osteotomy 16 months after spinal surgery to treat his residual pelvic obliquity and the ischial pressure injury, which healed completely. At the 1-year follow-up visit, there were no further signs of pressure injury.

Conclusion:

This case report describes transiliac-shortening osteotomy as a viable treatment option for non-healing ischial pressure injuries secondary to fixed pelvic obliquity.
SLP Method Boosts Production Efficiency by 16% in Indonesia
Authors: Kusuma Dewi Fortuna , Cahyana Atikha Sidhi
Published: May 2024

The study on improving the facility layout at CV. Surya Mega Yokasa demonstrated that the Systematic Layout Planning (SLP) method significantly enhances the efficiency of the production process, with a total reduction in material displacement distance by 13.45 meters and an efficiency increase of 16%. These findings imply that careful consideration of workflow and qualitative factors in layout planning can markedly optimize production flow and reduce congestion. However, the study did not factor in the Material Handling Costs (MHC), suggesting that future research should integrate MHC analysis to provide a more comprehensive evaluation of layout effectiveness and further optimize production efficiency.
Highlight:

Efficiency Boost: SLP reduced displacement by 13.45m, increasing efficiency by 16%.
Improved Workflow: SLP method improved production flow, reducing congestion.
Future Focus: Include Material Handling Costs for better layout evaluation.

Keywoard: Systematic Layout Planning, Blocplan, Production Efficiency, Material Flow, Facility Layout
Self-Brain Networks in Toddlers with Autism Spectrum Disorder
Authors: Zuo Xi-Nian , Zhang Gongwei , Zhou Liwei , Nie Jingxin , Wang Xin , Han Junrong , Wu Hang , Zhang Xinyu , Yang Longyu , Liu Yunhe , Liao Qianyi , Li Peng , Zhao Cailei , Zhou Zhenhui , Zhou Jiaxiu , Qin Pengmin , Weng Xuchu
Published: May 2024

As early as 18-24 months, self-processing has been reported abnormal in autism spectrum disorder (ASD), echoing a key period for the emergence of self-awareness. However, the neural mechanisms underlying this phenomenon remains unclear. The self-processing was supposed integrating three nested levels: the interoceptive-self which represents bodily internal state, the exteroceptive-self which links the internal and external environment and marks a key step in self-awareness development, the mental-self which represents the mental world built on the abstract relationship between the internal and external environment. Therefore, we assumed that ASD may show abnormal exteroceptive-self from 18-24 months and then develop the disorders of mental-self with their growing. To test this hypothesis, resting-state functional magnetic resonance imaging data from both ASD and typically developing controls (TDC) were collected and divided into two age groups: 18-24 months and 25-48 months. In ASD, functional connectivity revealed hyperconnectivity within exteroceptive-self network; graph theory analysis revealed atypical nodal topological properties in both exteroceptive- and mental-self network. Based on these findings, a support vector machine (SVM) model was trained to distinguish ASD from TDC for each age groups, and then validated with independent datasets. The SVM models achieved accuracy rates of 88.2% (training) and 75% (testing) for the 18-24 months group, and 86.7% (training) and 84.6% (testing) for the 25-48 months group while SVM models based on the non-self-related brain regions cannot achieve similar accuracy. These findings disclose the abnormal information processing within self-network in brains of toddlers with ASD, and provide potential neuroimaging markers for its early detection and future translation.
A 2D Zn-MOF with Oxygen Functional Sites as An Efficient Luminescent Sensor for Detecting Cr2O72− in Water Media and HEPES Biological Buffer Solution
Authors: Niu Xue-Li , Yang Hua , Kong Lingqian , Dou Jian-Min , Wu Qian
Published: May 2024

Efficient detection of toxic heavy metal anions Cr2O72− residue in water media is of great significance due to its severe damage to ecosystem and human health. Herein, a new 2D (two-dimensional) luminescent metal–organic frameworks (MOFs) {[Zn2(bmida)(phen)]·H2O}n (abbr. Zn-MOF) (1,10-phen = 1,10-phenanthroline, H4bmida = N-(phosphonomethyl)iminodiacetic acid) with rich oxygen functional sites was constructed and structurally characterized. Notably, this Zn-MOF as an efficient luminescent sensor can detect Cr2O72− both in water media and HEPES biological buffer solution with high selectivity and sensitivity, and good cyclic stability. The corresponding detection limit (LOD) of Zn-MOF towards Cr2O72− is as low as 1.21 and 5.46 μM with large quenching constant (Ksv), respectively. The LOD in H2O solution is lower than the benchmark of drinking water recommended by United States Environmental Protection Agency (USEPA, 1.92 μM). Moreover, a possible weak interaction mechanism induced by competitive energy absorption is suggested by multiple experiments.
Endoscopic Treatment of Pilonidal Sinus Disease in Paediatric Patients – A Study in Western Australia
Authors: O’Sullivan Jessica Lesley , Gera Parshotam
Published: May 2024

Background
Pilonidal disease is considered a spectrum of disease ranging from acute abscesses to a chronic
state most often associated with draining sinuses in the gluteal fold. An increasing prevalence is
seen in children with 3 out of every 250,000 children developing pilonidal sinus disease
(PSD). Although this is a common disease within general and paediatric surgery departments
worldwide, there is yet to be an agreement on a ‘Gold Standard ‘of treatment. Minimally invasive treatment techniques such as EPSiT are a more recent development for pilonidal disease that are showing promising results.
Method
This study is a retrospective study of children and adolescents who underwent excision of pilonidal disease using EPSiT by a single paediatric surgeon in Western Australia. The primary outcome measure is recurrence, secondary outcomes include complications, length of hospital stay, time to return to school/work, post-operative pain, and time to complete wound healing.
Results
No patients suffered recurrence or wound complications at mean follow up of thirteen months. No patients were readmitted to hospital for procedure related complications. All patients reported complete wound healing at an average of twenty-eight days and definitive total wound closure at six weeks post operatively. All patients reported the ability to resume daily activities at 2-4 days post operatively.
Conclusion
PEPSiT is a promising method of treating paediatric PSD and may represent a
new 'Gold Standard’ of treatment in these patients. Our results were comparable to
other studies in the literature. However, more studies and large-scale randomized control trials
are necessary in the paediatric patient cohort.
Level of Evidence: IV
ISOLATED GALLBLADDER PERFORATION FOLLOWING BLUNT ABDOMINAL TRAUMA
Authors:   Department of Visceral Surgery, University Hospital of Agadir, Ibn Zohr University, Agadir, Morocco., El Amine Ratbi , Mohamed Ouazni ,   Department of Visceral Surgery, University Hospital of Agadir, Ibn Zohr University, Agadir, Morocco., Mehdi Soufi ,   Department of Visceral Surgery, University Hospital of Agadir, Ibn Zohr University, Agadir, Morocco.
Published: May 2024

Isolated gallbladder rupture due to abdominal blunt trauma is a rare condition due to its anatomical location and includes 0.5- 0.6% of all intra-abdominal injuries. Most often the diagnosis is delayed and mostly revealed during the surgeries. We report a case of isolated gallbladder due to abdominal blunt trauma in a 28-year-old man,whose the diagnosis was delayed last 5 days and made intraoperatively. Cholecystectomy is the surgical treatment.
MOLECULAR CLASSIFICATION OF BREAST CANCER WITH IMMUNOHISTOCHEMICAL MARKERS
Authors:   Postgraduate Resident, Department of Pathology, Dr. Balasaheb Vikhe Patil Rural Medical College, Pravara Institute of Medical Sciences, Deemed to be University, Loni., Gadekar Yogita , Dongre S.D ,   Professor and Head of Department, Department of Pathology, Dr. Balasaheb Vikhe Patil Rural Medical College, Pravara Institute of Medical Sciences, Deemed to be University, Loni., Baviskar Bharti ,   Professor, Department of Pathology, Dr. Balasaheb Vikhe Patil Rural Medical College, Pravara Institute of Medical Sciences, Deemed to be University, Loni.
Published: May 2024

Introduction: Breast cancer is one of major cause of female mortality worldwide. The molecular classification has considered to mainly aid clinicians to better approach the prognosis and also to formulate treatments for different prognosis. According to St.Gallen symposia, five intrinsic subtypes are established: luminal A-like, luminal B-like, HER2 positive & triple negative. The aim of study is to classify carcinoma of breast into molecular classes using IHC markers in carcinoma breast. Material & Methods: This is descriptive, cross sectional study. Histologically diagnosed cases of carcinoma of breast by H&E stain were stained by IHC markers ER, PR, HER 2/neu, ki67 & CK5/6 & interpreted. Result and Discussion-Out of 134 cases diagnosed as carcinoma breast,120 cases belongs to IDC, NST subtype. Maximum cases were from age group of 41-60 years. Grade II was most commonly seen among the total cases in present study followed by grade 3 and grade 1 respectively. HER 2 enriched provides better therapeutic options like treatment with Herceptin for HER2/neu positive cases. Conclusion: The molecular classification using IHC surrogate markers showed more number of cases in subtype HER2(+) Enriched, luminal B, Her2(+) and triple negative.
THERAPEUTIC EFFECTS OF VITAMIN D IN PATIENTS WITH ACTIVE INFLAMMATORY BOWEL DISORDER: EXAMINING THE RELATION BETWEEN VITAMIN D INTAKE AND DISEASE ACTIVITY
Authors:   MBBS Kamineni Academy of Medical Sciences and Research Centre., Nimmagadda Rithish , Priyatha Vemparala ,   MBBS All India Institute of Medical Sciences (AIIMS), Bhubaneswar, India., Firdous Shaik Bushra ,   M.D Internal Medicine Piedmont Macon., Ernest-Okonofua Excel ,   IgbinedionUniversity, Okada, Edo State., Ahmed Mohammed Sami Mahroq Omar ,   Gulf Medical University, Ajman, United Arab Emirates., Oyindolapo Ganiyu Shakirat ,   University of Texas Rio Grande Valley Knapp Medical Center, Weslaco, Texas., Farouk Pousette ,   California Institute of Behavioral Neurosciences and Psychology.
Published: May 2024

Background: Inflammatory bowel diseases include Crohns and ulcerative colitis . They have become more common diseases and lifelong problems for individuals, despite the availability of many medication and surgical alternatives. To achieve the optimum benefits, vitamin D is used to lower disease activity. Objective: This study helps us show the impact and therapeutic effect of vitamin D in active Inflammatory bowel disorder . Methodology: PubMed, the Cochrane Library, and ScienceDirect are the databases searched for randomized controlled trials (RCTs) and reviews. After quality appraisal and cross checking the literature, this systematic review is carried out grounded on Preferred Reporting Items for Systematic Review and Meta-Analysis 2020 (PRISMA 2020) guidelines. A total of 11 studies which include nearly 1500 subjects showed that theres an positive association between VIT D and disease severity . Results: The results suggests that vitamin D administration can significantly lower the inflammation in the gut. An inexpensive VIT D reduced inflammation and drastically bettered the patient lives. Conclusion: To completely understand the complex Relationship between Vitamin D and Inflammatory Bowel Disorder, Large population-sizes trials are highly demanded for further identification and understanding the efficacy of vitamin D with conventional therapy.
POLITICAL CULTURE AND INTRA-PARTY SECURITY IN MONGOLIA
Authors:   Ph.D, Leading Academic Researcher Mongolian Academy of Sciences., Oidov Khatanbold , Batmunkh Purevsuren ,   MA Student, National University of Mongolia.
Published: May 2024

In any democratic country, political parties play an important role in the development of society and are a participating institution with a special role in representative democracy. In this context, parties play a major role in supporting fair competition in politics and also have an important influence on ideological and state regulation of politics. Therefore, political parties are obliged to fulfill their obligations to the society strictly within the legal and legal framework, to report on their financial support in accordance with the established procedure and to be able to be accountable to the society. In this context, how will Mongolias political parties influence the formation of the following functional approaches - the will of the people and the formation of public opinion improving citizens political education how to ensure citizens active participation in political life preparing citizens capable of performing public service and taking responsibility participating in elections as a candidate how to harmonize their political goals and agenda with the governments policies and decisions In this article, we have sought to clarify the following functional approaches. The results of the main and additional studies selected and conducted by the authors themselves are used, analyzed and presented.
EVALUATION OF STAINLESS-STEEL CROWN CEMENTED WITH GLASS IONOMER CEMENT, RESIN MODIFIED GLASS IONOMER CEMENT AND NEW SELF-ADHESIVE RESIN CEMENT: AN INVITRO STUDY
Authors: Cheday Gurung Karma , Dua Parminder , Mangla Ritu , a Neha , Sharma Divya , b Ridhima
Published: May 2024

Aim: To assess and compare the retentive strength of stainless-steel crown cemented with glass ionomer cement (GC Fuji I), resin modiifed glass ionomer cement (Relyx Luting 2) and new self-adhesive resin cement (RelyX U200). Materials and Method: Forty-five extracted primary teeth were mounted on acrylic blocks. Stainless steel crowns were selected for each tooth. Three cements compared in this in vitro study were glass ionomer cement (GC Fuji I), resin modified glass ionomer cement (RelyX Luting2) and self-adhesive resin cement (RelyX U200). Teeth were randomly divided into three groups of 15 samples each. Retentive strength was tested using Instron Universal testing machine. The retentive strength values were recorded and calculated by the formula: Load/Area. Results: RelyX U200 (Self-adhesive resin cement) showed significantly higher retentive strength than rest of the two cements. No significant difference was found between RelyX Luting 2 (Resin modified glass ionomer cement) and GC Fuji I (Glass ionomer cement). Conclusion: The finding of our study suggests that self-adhesive resin cement was better than resin modified glass ionomer cement and glass ionomer cement. RelyX U200 (Self-adhesive resin cement) can be used for the cementation of stainless-steel crowns.
Strategic working capital management in Polish SMES: Navigating risk and reward for enhanced financial performance
Authors: Morshed Amer
Published: May 2024

This study examines the impact of operating capital management (WCM) strategies on the monetary execution of small and medium-sized enterprises (SMEs) in Poland, with a particular focus on finding the correct equalization between liquidity and benefit. The review utilizes relapse investigation to survey the effect of forceful and conservative (WCM) techniques on the benefit and fluidity of 4,891 Polish SMEs from 2012 to 2021, as measured by an informational index of budgetary and operational information. The results demonstrate a noteworthy connection between WCM improvements and budgetary results. However, aggressive actions do not just mean higher earnings; they also involve heavier financial risks. On the other hand, cautious methods are linked with stronger financial stability but may lead to lower profit. According to the survey, when cash conversion cycle (CCC) days fall by 1%, return on total assets (ROA) can increase by approximately 1:0 percentage points. This demonstrates again that WCM is very important in improving company profits. These findings have implications for academics, practitioners, and government officials.
Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation
Authors: Bogachev V. Yu. , Boldin B. V. , Golosnitskiy P. Yu. , Turkin P. Yu. , Dizengof I. M. , Kobzarev D. A. , Tsukan V. Yu.
Published: May 2024

The problem of studying the pathology of mesenteric fat of the small intestine in surgical practice has not yet received enough attention. A number of questions remain unresolved regarding the etiology and pathogenesis of mesenteric diseases, their possible connection with benign and malignant diseases, methods of their laboratory and instrumental diagnosis, possible options for conservative and surgical treatment, as well as systematization and structuring of the classification. One of the poorly studied representatives of diseases of the mesentery of the small intestine continues to be Sclerosing mesenteritis, characterized by various histological variants of damage to mesenteric fat and a varied nonspecific clinical picture. Taken together, this leads to certain difficulties in diagnosis, patients seeking access to doctors of various profiles, which ultimately negatively affects the results of treatment and can lead to social maladjustment and possible disability. Reports on the occurrence of this pathology in the medical literature are few and, as a rule, describe extremely rare clinical cases. However, in recent years, the frequency of detection of this pathology continues to grow steadily, which is associated with the progressive aging of the population, a high degree of surgical activity in relation to urgent diseases of the abdominal organs, and the improvement of instrumental diagnostic methods. Issues of etiology, pathogenesis, differential diagnosis of this disease and its possible connection with the paraneoplastic process currently continue to cause debate. Further accumulation of clinical experience, a better understanding of the pathogenesis of the disease, and improvement of imaging techniques will allow us to develop clearer diagnostic and clinical criteria, narrow the diagnostic search and, ultimately, improve and standardize treatment. The article provides a review of the literature on this rare surgical pathology, presents our own clinical observation, and discusses diagnostic issues and treatment options for this disease.
Supportive local treatment of diseases of the distal colon of various inflammatory genesis in the outpatient department
Authors: Belik B. M. , Kovalev A. N. , Mirkin Ya. B. , Ponomarenko M. E. , Kryachko A. A. , Skorlyakov V. V. , Babiev V. F. , Kivva A. N.
Published: May 2024

Introduction. Currently, along with the improvement of the scheme of combined drug therapy with first-line anti-inflammatory drugs, important importance is attached to adjuvant topical methods of treating diseases of the distal colon of various inflammatory genesis.

Aim. Evaluate the clinical efficacy of the drug on sodium hyaluronate as an adjuvant topical agent in the complex treatment of patients with diseases of the distal colon.

Materials and methods. A comparative analysis of the results of drug treatment of 97 patients with diseases of the distal colon of various inflammatory genesis, which were divided into two groups, was carried out. In 46 (47.4%) patients of the I (control) group, standard drug therapy with basic anti-inflammatory drugs was performed; 51 (52.6%) patients – II (main) group, the standard program of drug treatment was supplemented with instillations into the rectum of the drug on sodium hyaluronate (0.8 mg of hyaluronic acid in 1 ml). The comparative assessment of the results of treatment took into account the severity of clinical, laboratory and endoscopic manifestations of the disease.

Results. In patients of the main group, there was a significant reduction in the healing time of erosions and ulceration of the mucous membrane of the distal colon compared with patients in the control group (29.4 ± 5.7 days, respectively, versus 52.8 ± 6.2 days). Also, in patients of the main group, it was possible to achieve stable clinical and laboratory remission of the disease at an earlier time, restoration of patients’ ability to work, and improvement of their quality of life.

Conclusion. The results obtained by us allow us to recommend the drug on sodium hyaluronate as an additional topical drug for the medical treatment of chronic diseases of the distal colon of various inflammatory genesis in outpatient settings.
Comparative morphological and morphometric analysis of the structure of the wall of the calf venous collectors
Authors: Sannikov A. B. , Morozova O. N. , Shaydakov E. V.
Published: May 2024

Introduction. Development of venous pathology of the lower extremities is based on morphological changes in the vascular wall. Further structural restructuring of the vein wall in chronic venous insufficiency will depend on the initially present differences in the structure of their walls.

Aim. To conduct a comparative analysis of morphological and morphometric features of the structure of the walls of the main venous collectors of the lower leg: the great saphenous vein, intramuscular veins, posterior tibia veins and poplitea vein.

Materials and methods. Histological studies were carried out on autopsy material of the veins of 32 people who died from various causes aged 35 to 50 years and 10 amputated limbs. Morphological studies of the venous wall were carried out by light microscopy with digital photo processing.

Results. A quantitative comparative analysis of morphological changes with the determination of the volume fraction of smooth muscle and connective tissue elements of various membranes of the venous wall, as well as measurement of the total thickness of the vascular wall and its ratio to the lumen of the veins showed statistically significant differences at a significance level of p < 0.05.

Discussion. Despite the similarity of the general morphological picture of the structure of various venous collectors of the lower leg, structural differences were established, which concerned the volume fraction of the presence of both smooth muscle and connective tissue elements.

Conclusion. The comparative qualitative and quantitative statistical analysis of morphological and morphometric features of the structure of the walls of the main venous collectors of the lower leg allows us to make an assumption about the unequal role of individual main venous collectors in the work of the muscular-venous pump of the lower leg as a whole.
Assessing the effects of dam regulation on multiscale variations in river hydrological regime and ecological responses
Authors: Wang Hongxiang , Bai Xiangyu , Yang Huan , Jiao Xuyang , Huang Lintong , Guo Wenxian
Published: May 2024

Using a combination of the long short-term memory model and hydrological change indicators, this study proposes an assessment framework at inter-annual and intra-annual scales to quantify the hydrological regime changes and ecological event responses caused by the regulation of the Three Gorges Dam (TGD) in the upper reaches of the Yangtze River. The results indicate that during the post-TGD period (2004–2019), 2 indicators of the natural flow regime undergo a high degree of alteration at the inter-annual scale, which increase to 12 when regulated flows are considered. Furthermore, we find that while climate and incoming water change significantly reduces the annual flow and monthly flow during the flood season, it increases the complexity (79%) and ecodeficit at the seasonal scale (94%). Among the 32 indicators of hydrologic alteration, TGD is the dominant factor influencing changes in 20 indicators, increasing the magnitude of low-flow events, decreasing the frequency of high-flow pulses, and advancing the timing of 1-day minimum flow (43 Julian date). From the hydrological perspective, the altered rising water conditions due to TGD regulation may cause an average decrease of 19.5% in the fry abundance for the Four Famous Major Carps.
Development of an electrocoagulation method using alternating pulse current to treat wastewater generated by tanneries
Authors: Al Hariri Hassoun , Atallah Fouad , Hathal Mustafa M.
Published: May 2024

Electrocoagulation has several disadvantages, such as electrode passivation, generation of heat due to energy consumption, and significant sludge formation. The constraints restrict its application in the treatment of tannery effluent. Therefore, the introduction of alternating pulse current electrocoagulation (APC-EC) aimed to resolve these concerns. We conducted an empirical examination of the research, specifically focusing on the frequency and stirring speed. This study investigated the impact of different parameters on the effectiveness of removing chemical oxygen demand (COD), the turbidity of trivalent chromium, and the energy consumption of perforated aluminium (Al) electrodes. The implementation of the central composite design (CCD) within the surface response design technique has enhanced multiple operational parameters in the APC-EC process for the treatment of tannery effluent. By employing our advanced mathematical and statistical techniques, we successfully eliminated the highest levels of COD, chromium (III) ion, and turbidity, all while significantly reducing energy usage. As a result, we achieved the optimal conditions for our process. The components that were eliminated most rapidly at 11000 Hz, 576 rpm, and 30 minutes were COD (70.3%), turbidity (96%), and 89.56%. The surface response results provide a description of the frequency dynamics of APC-EC.
CARACTERIZAÇÃO DA PRODUÇÃO PATENTÁRIA DE UM INSTITUTO FEDERAL DE EDUCAÇÃO DO NORDESTE
Authors: Leal Raimundo Nonato , Oliveira Francisca Mesquita de , Rocha Lízia Barbosa , Feitosa Samylla de Moura
Published: May 2024

A criação de algo novo, que vá facilitar e melhorar em algum aspecto a vida humana, é sempre um desafio ante a quantidade de variantes implicadas. Diante disso surge a necessidade de regulamentação para a segurança do invento e do inventor, sendo o registo de uma patente a forma seguro de se resguardar. Este trabalho evidencia a importância da inovação nas Instituições Federais de Ciência e Tecnologia, através da realização do mapeamento no banco de dados do INPI, referente ao depósito de patentes inscritas pelo Instituto Federal do Piauí, no período de 2014 a 2021. Realizou-se um comparativo quantitativo no depósito de patentes a nível de Instituto Federais da região Nordeste a fim de nortear o IFPI perante os demais IFs da região.  O artigo demostra a importância das instituições como impulsionadores locais de inovações e foi identificado o quantitativo e as características de alguns aspectos importantes quanto ao mapeamento da quantidade de depósito de patentes, suas fases, a quantidade de depósitos publicados, suas parcerias, e suas áreas de conhecimento. A pesquisa demostra que o IFPI se tornou um promotor de inovação e um depositário de patentes, seus registros permitiram mapear a caracterização dos depósitos patentários em vários aspectos e não há ainda a concessão de nenhuma patente depositada, visto que é um processo lento. Feita a análise, indica-se que o registro de patentes no IFPI é um campo relativamente "novo" e passível de exploração pela pesquisa e tecnologia e com algumas melhorias pode se destacar para a região.