bluuebunny/crossref_metadata_2025 huggingface dataset:
Motivasi Latihan Pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur
Authors: Arista Wimpi , Martiani Martiani , Anggara Deffri
Published: March 2024

Penelitian ini bertujuan untuk mendeskripsikan Motivasi Latihan Pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur Penelitian ini merupakan penelitian deskriptif kuantitatif. Metode yang digunakan adalah survei. Populasi penelitian ini adalah remaja putri Motivasi Latihan Pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur yang berjumlah 18 orang Teknik pengumpulan data dengan menggunakan kuesioner. Hasil penelitian ini bahwa motivasi Instrinsik dari hasil angket dan telah di persentasekan dengan latihan pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur bahwa terdapat 8 orang remaja putri dengan presentase 44,44% yang memiliki motivasi instrinsik dalam Latihan Pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur yang memiliki katagori baik sekali. Sedangkan yang memiliki motivasi instrinsik baik ada 6 orang dengan presentase 33,33% dengan kategori baik. Apabila dilihat dari frekuensi dari tiap kategori, terlihat bahwa motivasi instrinsik remaja putri motivasi instrinsik dalam Latihan Pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur adalah “Baik Sekali”. Motivasi Ekstrinsik Latihan Pada Pemain Bola Voli Putri Di Desa Aur Ringit Kabupaten Kaur yang memiliki persentase 0 % dengan kategori baik sekali, sedangkan untuk persentase 11,12% dengan kategori baik, untuk kategori sedang yaitu 44,44%, sedangkan persentase 44,44% dengan kategori kurang untuk kategori kurang sekali itu 0, kategori yang tertinggi yaitu kategori “Sedang dan Kurang”.
Pengaruh Latihan Karet Ban Terhadap Kecepatan Tendangan Dollyo Chagi Pada Atlet Taekwondo Di Dojang Star Club Kota Bengkulu
Authors: Suwarningsih Bunga Tri , Asnawati Asnawati , Martiani Martiani
Published: March 2024

The purpose of this study was to influence the effect of rubber tire training on Dollyo chagi kick speed. Taekwondo athletes at Dojang star club Bengkulu City. The method used in this research is descriptive quantitative research this research design is in the form of experiments with the form of one group pretest and postest. The sample in this study were 35 taekwondo athletes Dojang star Club Bengkulu. The results of this study found that there was an increase in the results of dollyo chagii kicks after being given training using rubber tires. This is evidenced by the increase in the average kick results of the research sample. The average pretest kick was 51.25 while the average postest result was 60.11 from this value it can be seen that there was an increase in test results of 8.86. Based on the results of multiple linear regression tests, the effect of using rubber tires on dollyo chagi kick speed has an R Square value of .898, indicating a very strong influence. Meanwhile, based on the results of the hypothesis test, it is known that the significant value of 0.004 indicates that 0.04 ≤ 0.05 so that the results of this hypothesis test show a significant effect between the pretest and posttest results, meaning that there is a significant effect of using rubber tires on the speed of dollyo chagi kicks at dojang star club athletes in Bengkulu city. So it can be concluded that the use of rubber tire media in increasing the speed of dollyo chagi tendengan is proven by the increase in test results after treatment.
ANALISIS PELAKSANAAN PROGRAM LATIHAN PADA CABANG OLAHRAGA SEPAK BOLA BENTENG HB KOTA BENGKULU
Authors: Pratama Pratama , Juwita Juwita , Sumantri Ajis
Published: March 2024

This study aims to determine how the implementation of the football training program of Benteng HB Club Bengkulu City. This research uses Qualitative research methods. This research uses instruments in the form of questionnaires and interviews. The population in this study were 20 Benteng HB soccer players. The results of this study The training program is made by referring to the National Training Program Standards. In making training programs, the coach involves players in making football training programs. In the training program there are physical, technical and mental exercises. In implementing the training program, the coach refers to the previously made training program. In its implementation, all training programs are carried out by the Benteng HB football team.
Kontribusi Daya Ledak Otot Tungkai Terhadap Keterampilan Smash Pada Permainan Bola Voli Di SMPN 1 Ujan Mas Kabupaten Kepahiang
Authors: Utama Nyoman Indra , Syaputra Roni , Masterjon Masterjon
Published: March 2024

This study aims to determine the contribution of leg muscle explosive power to the ability to smash volleyball at SMPN 1 Ujan Mas, Kepahiang Regency. This type of research is correlational research. The research sample is 20 people. The instrument used in this study was the Explosive Power Test of Leg Muscles Against Smash Ability. Where the results of the explosive power of the leg muscles carried out by 20 people at SMPN 1 Ujan Mas, Kepahiang Regency, had the explosive power of the leg muscles as many as 1 person (5%) had the Very Good category. As many as 6 people (30%) have a Good category. As many as 7 people (35%) have the Enough category. As many as 3 people (15%) have the Less category and as many as 3 people (15%) have the Very Less category. Then it was continued with the Smash Skills test which was attended by 20 people at SMPN 1 Ujan Mas, Kepahiang Regency. 6 people (30%) had smash skills in the Good category. As many as 7 people (35%) have the Enough category. As many as 6 people (30%) have the Less category. As many as 1 person (5%) have the Less Once category. Thus the hypothesis which reads "There is a strong contribution between leg muscle explosive power and smash skills at SMPN 1 Ujan Mas, Kepahiang Regency" is accepted. This means that there is a Contribution of Leg Muscle Explosive Power with Smash Skills at SMPN 1 Ujan Mas, Kepahiang Regency
Sosialisasi dan Pembuatan Elisator Biosaka Guna Mendukung Pertanian Berkelanjutan Pada Kelompok Wanita Tani Wirajaya Sarilamak
Authors: Sari Deliana Andam , Illahi Ayu Kurnia , Karmaita Yummama , Kurniasih Dedeh , Anidarfi Anidarfi
Published: March 2024

Masalah utama petani Indonesia dalam budidaya tanaman adalah cara budidaya yang besifat konvensional, dimana menggunakan pupuk an-organik untuk meningkatkan produktivitas tanaman. Kegiatan sosialisasi pembuatan elisator biosaka dilaksanakan tanggal 28 Juli 2023 dan 15 Agustus 2023. Metode pelaksanaan pertemuan pertama: sosialisasi pembuatan elisator biosaka di saung pertemuan KWT Wirajaya, kegiatan berupa diskusi, pengarahan mengenai proses pembuatan elisator biosaka. Sosialisasi dilakukan kepada anggota KWT dengan materi manfaat menggunakan elisator biosaka, peran elisator biosaka terhadap tanaman. Pertemuan selanjutnya demonstrasi pembuatan Elisator Biosaka. Kegiatan selanjutnya pengaplikasian elisator biosaka pada tanaman jagung manis.  Tujuan pengabdian masyarakat: melalui pelatihan pembuatan Elisitor biosaka dapat mengedukasi petani tentang pemanfaatan bahan rerumputan yang tersedia di lingkungan guna mendukung pertanian berkelanjutan. Sosialisasi mengenai manfaat elisator biosaka, peran elisator biosaka terhadap tanaman dan pembuatan elisator biosaka pada KWT telah mengedukasi petani mengenai manfaat bahan rerumputan disekitar lingkungan. Anggota kelompok wanita tani Wira Jaya bisa membuat elisator biosaka guna diaplikasikan pada tanaman.
Analysis of the Current State and Development Trends of Social Infrastructure in the Kyrgyz Republic
Authors: Khamzaeva M. , Arzybaeva M. , Tashibekov T. , Dehkonov U.
Published: March 2024

Research relevance: the article examines the current state of the social infrastructure of the Kyrgyz Republic and the trends of its development over the past 5 years. Research objectives: to identify problems and propose priority directions for the development of social infrastructure. The analysis of statistical data of the main indicators of healthcare of the Kyrgyz Republic from 2018 to 2022, including the number of secondary medical personnel, the number of hospitals, centers of family medicine, groups of family doctors, the number of paramedics and midwives, and first aid stations. Research results: electricity is the main type of improvement covering the entire territory of the republic. In 2022, access to the water supply network will be 71.3%, and to the sewage system — 62.2% of the housing stock, both indicators tend to grow steadily. Conclusions: an important priority in the regions should be the creation of the infrastructure of settlements, which ensures the improvement of the living conditions of the population.
Small Entrepreneurship and Innovations in Azerbaijan
Authors: Musayev A.
Published: March 2024

Small businesses play a critical role in the global economy by driving innovation, creating jobs and contributing to local communities. Small businesses, defined by their size, typically with fewer employees and lower revenues than large corporations, are diverse and dynamic businesses operating in a variety of industries. Small businesses in Azerbaijan are growing steadily, thanks to a combination of government initiatives, a growing startup ecosystem and a young, tech-savvy population. The country, located at the crossroads of Eastern Europe and Western Asia, views innovation as a key factor in economic development. Government support for small businesses has played an important role in the development of entrepreneurship. Initiatives such as tax incentives, financing programs and simplified regulatory processes are aimed at creating an enabling environment for startups. Azerbaijan’s strategic location and rich natural resources have also opened up opportunities in various sectors, from agriculture to technology. In recent years, the field of technology startups in Azerbaijan has been gaining momentum. Baku, the capital, has become a hub of innovation, hosting events, incubators and accelerators that nurture local talent. Young entrepreneurs are using technology to create solutions that solve both local and global problems. Fintech, agritech and medtech are just some of the sectors that are seeing notable innovation. Despite progress, challenges remain such as access to finance, market competition and the need for further infrastructure development. However, the entrepreneurial spirit in Azerbaijan remains strong, with a growing emphasis on collaboration, knowledge sharing and mentoring. As small businesses continue to drive economic diversification and technological progress, Azerbaijan is positioning itself as a promising landscape for innovative entrepreneurship.
Electronic Parliament and Information Relations
Authors: Semenov N. , Ismanov T.
Published: March 2024

The article discusses the theoretical and legal aspects of the origin and development of the concept of “electronic parliament” and information relations, where “electronic parliament” is a new vision in the development of the “electronic state” with the ability to monitor processes in parliament, obtain information data and conduct information interaction with deputies directly, which indicates the practicality, flexibility and effectiveness of this concept. Currently, there are certain problems that should also be considered by studying the experience of introducing the concept of “electronic parliament” in various states. Practical developments in the field of online voting in the USA, Japan and Estonia are outlined. The legal features of the formation of the concept of “electronic parliament” have been identified, and the implementation of the concept of “electronic parliament” will contribute to the involvement of citizens in the system of governance of society and the state.
Some Issues of the Participation of Children in Conflict With the Law in the Consideration of Criminal Cases by Courts
Authors: Otonbaeva R.
Published: March 2024

This article discusses problematic issues related to the participation of a child in conflict with the law in criminal cases considered by the court. The author focuses his attention on such issues as the mandatory participation of the child in the trial, the unacceptability of a trial in absentia; factors are shown that have a significant impact on the activity or passivity of the participation of children in conflict with the law when considering cases by the courts. The author reveals the issues of children's awareness of their rights and responsibilities specifically in court proceedings, which otherwise may lead to a violation of the principles of criminal proceedings, such as: spontaneity, comprehensiveness, completeness and objectivity of the study of the circumstances of the case. In order to ensure confidentiality, it is proposed that all such trials be conducted in closed form and that further work is necessary to ensure the rights and legitimate interests of children who are in conflict with the law in criminal cases considered by the courts.
Features of Teaching Written Speech in Russian Language Lessons in a Kyrgyz School (Based on the Example of 7th Class)
Authors: Aknazarova G.
Published: March 2024

The article discusses the features of teaching writing in Russian as a second language lessons. Definitions of the concepts “writing” and “written speech” in scientific and methodological literature are given. Particular attention in the article is paid to the methods and means of developing written speech in Russian language lessons in a Kyrgyz school. For this purpose, requirements for teaching written speech are given in the Subject Standard for the Russian language for schools with Kyrgyz as the language of instruction. Considerable attention is paid to the analysis of the textbook “Russian Language” for the 7th grade of schools with the Kyrgyz language of instruction in order to identify a system of gradual formation of skills to write texts of a productive nature. The given examples of tasks aimed at developing written speech in accordance with the requirements of the Subject Standard for the Russian language for the Kyrgyz school indicate that the textbook provides for step-by-step work on the formation of students’ written speech. A variety of exercises are aimed at creating texts of a productive nature (short reasoning, descriptive text based on the text read, texts based on a given beginning or end). The skill of creating a written statement of a productive nature is important in the process of developing a student’s communicative competence. Mastery of written speech is a prerequisite for full communication in the target language (Russian), therefore it is necessary to develop the skills and abilities of written speech consistently and constantly. Teaching productive written speech in the process of learning Russian as a second language allows you to develop cognitive and linguistic skills and form the written communicative competence of students.
The Practical Value of Intensive Training Used in the Development of Communication Skills of Mathematics Students in Professional English
Authors: Bekmatova Z. , Mukambetova A.
Published: March 2024

The article discusses the features of the methods that mathematics students use to successfully implement communication skills in English. The objectives of the study are to reveal their influence on the development of professional communication skills of mathematics students through the views of scientists studying it, and propose aspects to be tested in practice. The article explains the objective aspects of the need to use such methods to achieve the intended result of teaching English in higher mathematical vocational education in Kyrgyzstan, and also interprets its content related to social and social conditions. Due to the fact that in many educational institutions of the country it is not clear what the internal content should be, the methods used in English classes currently retain their traditional forms. Practical value of intensive training is combined with the goal of creating professional communication in English at the necessary level for mathematics students to withstand international competition, and examples illustrate the content that needs to be accomplished in practice.
Classes of the Kazakh National Sports Togyzkumalak Game - a Factor in the Study of Educational and Cognitive Purposes of Students
Authors: Azimbaev Zh.
Published: March 2024

Issues related to the study of educational and cognitive motives among primary school students at secondary schools during the classes of the Kazakh national sports Togyzkumalak game are considered. The result of the work is an increase in cognitive activity and academic performance of students.
The Phenomenon of Loneliness in the Context of Philosophical-Religious Ideology
Authors: Salmorbekova R. , Alymbaev A. , Nusubalieva G.
Published: March 2024

This article explores the phenomenon of loneliness in the context of a philosophical and religious worldview. The authors analyze the relationship between loneliness and religious experience, and also explore how religious and philosophical ideas and practices can influence the experience and overcoming of loneliness. The article outlines the main provisions of various philosophical and religious trends related to the phenomenon of loneliness. Considers the contribution of authors such as Martin Buber, Friedrich Nietzsche, Jean-Paul Sartre and others in understanding loneliness and its connection with religious practice. Various religious traditions and beliefs are analyzed as resources and approaches for overcoming loneliness. In conclusion, the article summarizes and draws preliminary conclusions about how philosophical and religious worldview can influence the perception and overcoming of loneliness. She calls for further research on this topic and takes into account its importance for human development in society.
The Concept of “Dreams (While Sleeping)” in the Proverbial Context of the Russian and Kyrgyz Languages
Authors: Berdibaeva N. , Chekirova A.
Published: March 2024

This article conducts a linguistic and cultural analysis of proverbial expressions, we tried to identify the specifics of linguistic verbalization of the linguistic and cultural concept of “dreams (while sleeping) / сон (Russian) / түш (Kyrgyz)” in the Russian and Kyrgyz linguistic proverbial space. The combination of sustainable forms produces a proverbial space of language, which reflects the entire history of life, way of life and experience, folk observations, conclusions, traditions and customs of each nation. By conducting linguistic studies of each language, linguists identify the ethnocultural characteristics of each language, depending on such extralinguistic factors as: geographical location, mental processes in the consciousness of a certain ethnic group and worldview. The relevance of this survey is the importance of the linguistic and cultural concepts, semantic descriptions of the features of Russian and Kyrgyz paroemia, which are an integral part of the national linguistic picture of the world. The concepts of “dreams (while sleeping) / сон (Russian) / туш (Kyrgyz)” considered by are an important state of human existence, the basic concept of any linguistic culture.
On Toponymy in the Epic of Manas
Authors: Dzhumaeva Zh.
Published: March 2024

The article provides a linguistic study of some ideas about the origin of toponyms in general, their etymology and history. The names of land and waters pass through a long period of time, and some names change from one name to another (for example, from one language to another) depending on time and events. Similar phenomena can be seen in detail in toponyms found in the Epic of Manas. Academician Tugelbay Sydykbekov, a writer and prose writer, also spoke about differences in the pronunciation and spelling of toponyms in the epic. In particular, he noticed that the toponyms in the Epic of Manas speak of the ancient traces of our people. An etymological and historical analysis of the names of some places has been carried out by comparing the views of the author with the linguistic analysis of linguists. Of interest is the etymology of the names of some places mentioned in the article. Not being a professional linguist, the ideas of T. Sydykbekov, which led to a certain linguistic analysis, require deep linguistic research.
The Relationship Between Capsaicin in Chili Pepper and Cancer: A Comprehensive Insight
Authors: Şanlıer Nevin , Irmak Esra , Ejder Zeynep Bengisu
Published: March 2024

Capsicum plant consists of savage and tame types, and there is a substance named the capsaicin that causes burning sensation of the bitter peppers. Capsaicin has many effects in the body. In addition to its antioxidant and anti-inflammatory properties, it has benefits such as cancer prevention, reducing blood pressure, having analgesic effects in the body. There are different capsaicinoids such as dihydrocapsaicin, nordroydrocapsaicin, homocapsaicin in nature. These capsaicinoids provide anti cancer activities by interacting with key signal molecules. Capsaicin can suppress the growth of cancer cells by changing the expression of the relevant genes of cancer cells. In summary, the capsaicin

ensures anticancer activity by suppressing the proliferation, growth in cancer cells and to induce apoptosis which inhibit the metastasis. This situation can provide promising new treatment approaches in common and fatal cancer species today. This article revises the relationship between capsaicin and different types of cancer, anti cancer effect of capsaicin. Therewithal, studies examining the treatment of different cancer cells with various doses of capsaicin are included. Capsaicin can suppress the growth of cancer cells by changing the expression of the relevant genes of cancer cells.
Is Cranial Imaging Necessary in Children with First-Time Focal Seizures?
Authors: Tekeli Aysun , Öztürk Betül , Bodur İlknur , Akca Çağlar Ayla , Göktuğ Aytaç , Atasoy Ergin , Eksioglu Ayse Secil , Karacan Can Demir , Tuygun Nilden
Published: March 2024

Objective: Seizures in children represent a common cause of admission to the emergency department. This study aimed to determine clinically significant intracranial abnormalities in children presenting to the pediatric emergency department with first-time focal seizures.

Methods: Patients aged 1 month-18 years, who presented to the pediatric emergency department with first-time focal seizures between 2009 and 2019, were retrospectively screened. Patients with a history of trauma, cases in which focal neurological signs could not be assessed, and patients with pre-existing structural brain or neurological abnormalities, and metabolic disorders were excluded from the study. Cranial computed tomography findings were re-evaluated by a pediatric radiologist. The fourth and fifth-level according to the classification of the International League Against Epilepsy were interpreted as urgent intracranial pathologies requiring medical or surgical intervention. The univariate analysis was performed using the chi-square test for categorical data and the Mann-Whitney U test for continuous data.

Results: The mean age of the 121 patients was 46.8±44.4 months, and 52.9% were male. Clinically significant emergency intracranial pathologies were detected in the neuroimaging of eight patients. Intracranial masses, bleeding, and hematomas were the most common pathologies. The presence of focal neurologic findings and an age below six months were clinically determined as predictors of an urgent intracranial pathology.

Conclusion: We found the rate of urgent cranial pathologies to be 6.6% in patients presenting to the emergency department following the first focal seizure. Children younger than six months with focal neurological signs should be evaluated for emergency neuroimaging.
Evaluation of Stress Distributions in All Ceramic Conometric Single Crown Restorations: 3-Dimensional Finite Element Analysis
Authors: Vural Sinem , Evren Buket , Yıldız Coşkun
Published: March 2024

Objective: The aim of the study is to compare the effect of monolithic translucent zirconia ceramic (TZI) and monolithic lithium disilicate glass ceramic (LDS) restorative materials on stress distributions in implant components and surrounding bone tissues in implant-supported conometric single crown restorations with a conical connection system by using 3D finite element analysis.

Methods: Restorations produced with two different all-ceramic materials using a conometric abutment and a conometric cap on the implant with a conical connection system were placed in the maxillary right second premolar region. 3D finite element analysis was used to examine the amount and distribution of stresses in implant components, in cortical and cancellous bone tissues surrounding the implant and in crowns under vertical and oblique loading. For the statistical analysis one-way ANOVA and independent samples t-test were used (p
Electricity theft detection in smart grid using machine learning
Authors: Iftikhar Hasnain , Khan Nitasha , Raza Muhammad Amir , Abbas Ghulam , Khan Murad , Aoudia Mouloud , Touti Ezzeddine , Emara Ahmed
Published: March 2024

Nowadays, electricity theft is a major issue in many countries and poses a significant financial loss for global power utilities. Conventional Electricity Theft Detection (ETD) models face challenges such as the curse of dimensionality and highly imbalanced electricity consumption data distribution. To overcome these problems, a hybrid system Multi-Layer Perceptron (MLP) approach with Gated Recurrent Units (GRU) is proposed in this work. The proposed hybrid system is applied to analyze and solve electricity theft using data from the Chinese National Grid Corporation (CNGC). In the proposed hybrid system, first, preprocess the data; second, balance the data using the k-means Synthetic Minority Oversampling Technique (SMOTE) technique; third, apply the GTU model to the extracted purified data; fourth, apply the MLP model to the extracted purified data; and finally, evaluate the performance of the proposed system using different performance measures such as graphical analysis and a statistical test. To verify the consistency of our proposed hybrid system, we use three different ratios for training and testing the dataset. The outcomes show that the proposed hybrid system for ETD is highly accurate and efficient compared to the other models like Alexnet, GRU, Bidirectional Gated Recurrent Unit (BGRU) and Recurrent Neural Network (RNN).
Akkermansia muciniphila: a potential candidate for ameliorating metabolic diseases
Authors: Niu Huifang , Zhou Minfeng , Zogona Daniel , Xing Zheng , Wu Ting , Chen Rui , Cui Dandan , Liang Fengxia , Xu Xiaoyun
Published: March 2024

Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of Akkermansia muciniphila and the occurrence of metabolic diseases. A. muciniphila, a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of A. muciniphila in metabolic diseases. It also details the high efficacy and specific molecules mechanism of A. muciniphila and its derivatives in treating obesity, type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease.
Trichoderma harzianum prevents red kidney bean root rot by increasing plant antioxidant enzyme activity and regulating the rhizosphere microbial community
Authors: Guo Zhifen , Zhang Jiaxing , Liu Zhibin , Li Yu , Li Meng , Meng Qiuxia , Yang Zhiping , Luo Yuan , Zhang Qiang , Yan Min
Published: March 2024

Root rot is one of the main reasons for yield losses of red kidney bean (Phaseolus vulgaris) production. Pre-inoculation with Trichoderma harzianum can effectively lower the incidence of red kidney bean root rot. In this study, four treatments including CK (control), Fu13 (Fusarium oxysporum), T891 (T. harzianum) and T891 + Fu13 (T. harzianum + F. oxysporum) were arranged in a pot experiment to investigate how T891 affected the incidence and severity of root rot, plant growth, and changes of defense enzyme activity in red kidney bean plants. Community composition and diversity of the rhizosphere microbiota was evaluated through high-throughput sequencing, and co-occurrence network was analyzed. The results showed that when compared to the Fu13 treatment, pre-inoculation with T891 reduced the incidence and severity of red kidney bean root rot by 40.62 and 68.03% (p < 0.05), increased the root length, shoot length, total dry biomass by 48.63, 97.72, 122.17%. Upregulated activity of super-oxide dismutase (SOD), peroxidase (POD), catalase (CAT) by 7.32, 38.48, 98.31% (p < 0.05), and reduced malondialdehyde (MDA) by 23.70% (p < 0.05), respectively. Microbiological analyses also showed that F. oxysporum reduced alpha diversity resulting in alteration the composition of the rhizosphere microbial community in red kidney bean. T891 significantly reduced abundance of F. oxysporum, allowing the enrichment of potentially beneficial bacteria Porphyrobacter (ASV 46), Lysobacter (ASV 85), Microbacteriaceae (ASV 105), and Gemmatimonas (ASV 107), resulting in a more stable structure of the microbial network. The results of random forest analysis further revealed that ASV 46 (Porphyrobacter) was the primary influencing factor for the incidence of root rot after inoculation with T891, while ASV 85 (Lysobacter) was the primary influencing factor for the biomass of red kidney bean. In conclusion, T. harzianum promotes the growth of red kidney bean and inhibits root rot by improving plant antioxidant enzyme activity and regulating the rhizosphere microbial community.
Brain organoid protocols and limitations
Authors: Zhao Helen H. , Haddad Gabriel
Published: March 2024

Stem cell-derived organoid technology is a powerful tool that revolutionizes the field of biomedical research and extends the scope of our understanding of human biology and diseases. Brain organoids especially open an opportunity for human brain research and modeling many human neurological diseases, which have lagged due to the inaccessibility of human brain samples and lack of similarity with other animal models. Brain organoids can be generated through various protocols and mimic whole brain or region-specific. To provide an overview of brain organoid technology, we summarize currently available protocols and list several factors to consider before choosing protocols. We also outline the limitations of current protocols and challenges that need to be solved in future investigation of brain development and pathobiology.
To Remind or Not to Remind During Recruitment? An Analysis of an Online Panel in Germany
Authors: Klee Bianca , Costa Daniela , Frese Thomas , Knoechelmann Anja , Meyer Gabriele , Meyer Thorsten , Purschke Oliver , Schildmann Jan , Steckelberg Anke , Mikolajczyk Rafael
Published: March 2024

Objective: To explore the role of reminders in recruiting and maintaining participation in an online panel.

Methods: 50,045 individuals from five German federal states were invited by regular mail to participate in the online study “Health-Related Beliefs and Healthcare Experiences in Germany.” Those who did not respond to the first attempt received a postal reminder. Comparisons of sociodemographic characteristics and responses were made between first-attempt respondents and those who enrolled after the second letter.

Results: After the initial letter, 2,216 (4.4%, 95%CI: 4.3%–4.6%) registered for the study; after a reminder 1,130 (2.5%, 2.3%–2.6% of those reminded) enrolled. Minor sociodemographic differences were observed between the groups and the content of the responses did not differ. Second-attempt respondents were less likely to participate in subsequent questionnaires: 67.3% of first-attempt vs. 43.3% of second-attempt respondents participated in their fourth survey. Recruitment costs were 79% higher for second-attempt respondents.

Conclusion: While reminders increased the number of participants, lower cost-effectiveness and higher attrition of second-attempt respondents support the use of single invitation only for studies with a similar design to ours when the overall participation is low.
The Extracts Derived from Artemisia japonica Thunb. Leaves Mitigate Oxidative Stress and Inflammatory Response Induced by LPS in RAW264.7 Cells through Modulation of the Nrf2/HO-1 Signaling Pathway
Authors: Ye Yueyu , Li Xiaomei , Chen Man , Wang Xia , Li Meiya , Jiang Fusheng , Zhang Xiaobo , Zhang Chunchun , Li Shiqing
Published: March 2024

Artemisia japonica Thunb. has been used as a traditional Chinese medicine and a vegetable for thousands of years in China. However, there are few reports on the chemical composition and biological activity of its leaves. Thus, this study aimed to evaluate the chemical composition, antioxidant and anti-inflammatory effects of water extracts of A. japonica leaves and their underlying mechanisms. A total of 48 compounds were identified in the water extract using UPLC-QTOF-MS2 analysis, with phenolic acids, particularly chlorogenic acid compounds, being the predominant components. The ethyl acetate fraction (EAF) contained most of the total phenolic content (385.4217 mg GAE/g) and displayed superior antioxidant capacity with the IC50DPPH•, IC50ABTS•+, and OD0.5reducing power at 10.987 μg/mL, 43.630 μg/mL and 26.883 μg/mL, respectively. Furthermore, EAF demonstrated potent antioxidant and anti-inflammatory effects in LPS-induced RAW264.7 cells by upregulating the Nrf2/HO-1 signal pathway. These findings highlight that A. japonica leaves possess remarkable abilities to mitigate inflammation and oxidative stress, suggesting their potential utilization as medicinal agents and food additives for promoting human health.
„Diena be nuotykių“: kasdienybės laiko tvarkymas vidutiniame Lietuvos miestelyje
Authors: Dambrauskaitė Ernesta
Published: March 2024

The article discusses the peculiarities of daily time management of people living in medium-sized Lithuanian towns. The prevailing concepts of everyday life are examined, focusing on the meanings of everyday life and time that emerge from the emic perspective of the respondents. Aspects of respondents’ daily routine rhythm, coordination of social time and planning of agendas are revealed. It shows how a resident of an average Lithuanian town organises their time in everyday life. The article analyses the data of the field survey conducted in the towns of Josvainiai and Ramygala from January 2020 to October 2020.
Новые местонахождения сосудистых растений из Красной книги Чукотского АО
Authors:   Institute of Biological Problems of the North, FEB RAS, Magadan, Mochalova O. A. , Chemeris E. V. ,   Papanin Institute for Biology of Inland Waters RAS, Borok, Yaroslavl Oblast, Bobrov A. A. ,   Papanin Institute for Biology of Inland Waters RAS, Borok, Yaroslavl Oblast
Published: March 2024

The authors present new data of the Chukotka south-east locations of 6 vascular plant species recorded in the regional Red Data Book. The greatest interest is the discovery of Lysiella oligantha, which is very rare in the region. Locations of 3 species from the list of the taxa whose condition required special attention have been exposed.
Identificação de patologias em pontes de concreto armado
Authors: Magalhães Bárbara Caiani de Lima , Costa Deckson Lacerda de Sousa , Barbosa Eduardo Campos , Carvalho Fabíola Helem da Silva , Silva Jorge Luiz Oliveira , Sucupira José Vitor Reis , Reinaldo Milena Moura , Conceição Samuel de Sousa , Brunoro Adrya , Santos Gabriel Cirqueira dos
Published: March 2024

Pontes de concreto armado desempenham um papel vital na infraestrutura das cidades, garantindo o fluxo seguro de pessoas e veículos. No entanto, ao longo do tempo, essas estruturas estão sujeitas a várias formas de degradação devido a fatores ambientais, uso intenso e falta de manutenção adequada. Este estudo tem como objetivo apresentar uma revisão sobre as principais patologias que afetam pontes de concreto armado. Dentre as patologias comuns estão a corrosão das armaduras, fissuras, desplacamento do concreto, entre outras. Cada uma dessas condições pode comprometer a integridade estrutural da ponte, levando a riscos de colapso e aumentando os custos de manutenção. Posto isso, como metodologia adotou-se a pesquisa bibliográfica qualitativa, de modo que, com as análises críticas e a construção de argumentos teóricos o estudo resultou em argumentos essenciais para planejar, prevê e solucionar possíveis patologias nas pontes e estruturas de concreto em geral.
Esclerose tuberosa: um relato de caso
Authors: Siqueira Junior Carlos Werneck Gomes , Oliveira Mariana de Souza , Valverde Thaisa Leite
Published: March 2024

A Esclerose Tuberosa (ET) é uma doença autossômica dominante, rara, que pode ser hereditária ou esporádica. Associa-se a mutações genéticas nos cromossomos 9 e 16 com alteração da função do complexo hamartina-tuberina e consequente descontrole do crescimento e proliferação celular. Trata-se de doença sistêmica e o diagnóstico baseia-se em critérios clínicos maiores e menores com eventual necessidade de teste genético. O seguimento é realizado através de exames de imagem direcionados, sendo o tratamento direcionado ao controle dos sintomas e prevenção de progressão da doença. O artigo objetiva relatar um caso de ET e informar sobre essa condição de saúde que é rara e necessita de diagnóstico precoce para controle da morbimortalidade associada.
Resultados imediatos e tardios na laparotomia em trauma abdominal
Authors: França Giovanna Gomes , Lopes Sálua Elisandra , Barbosa Carlos Cesar , De Souza Ana Clara Rodrigues , Alves Victor Gabriel Martinelli , Dantas Danilo Costa , Andrade Douglas Louzakan Pereira , Asseis Augusto César Romão , Loubet Murillo Barbosa , André Alancaster Silvério de Assis , Costa Frederico Lisita , De Almeida Filho Claiton Luiz
Published: March 2024

INTRODUÇÃO: O trauma abdominal representa uma causa importante de morbidade e mortalidade mundial. A realização de laparotomia para abordagens dos pacientes traumatizados é importante no aumento da sobrevida, no entanto, em virtude dos próprios riscos que apresentam-se inerentes ao trauma em si, situações como readmissões hospitalares por complicações cirúrgicas são, também, recorrentes. OBJETIVOS: avaliar os resultados imediatos e tardios em pacientes submetidos a laparotomia após trauma abdominal. METODOLOGIA: Trata-se de uma revisão integrativa na base de dados PUBMED utilizando os descritores ‘’Trauma AND Laparotomy’’ para artigos publicados entre 2018 e 2024. RESULTADOS: Identificou-se 1806 artigos, sendo selecionados 10 artigos que contemplavam o tema. A lesão abdominal ocorre aproximadamente em 33% dos pacientes traumatizados. A laparotomia é indicada em até 44% dos casos por instabilidade hemodinâmica. Essa modalidade de cirurgia pode estar relacionada a episódios de inflamação abdominal, líquido abdominal livre e lesão intestinal. CONCLUSÃO: A indicação da laparotomia deve seguir critérios bem definidos pela equipe cirúrgica, haja vista se tratar de um procedimento invasivo, sendo ideal avaliar a possibilidade de abordagens menos invasivas.
Aspectos epidemiológicos da Leishmaniose Visceral Humana nos municípios de Juazeiro/BA e Petrolina/PE no período de 2001 a 2020
Authors: Barreira Matheus Pereira , Marteis Letícia Silva , Da Silva César Augusto
Published: March 2024

Brasil destaca-se entre o conjunto de seis países que engloba cerca de 90% dos casos mundiais de  Leishmaniose visceral (LV), doença presente em aproximadamente 90 países. Este é um estudo observacional, retrospectivo e descritivo dos casos confirmados e notificados de LV humana, no período de 2001 a 2020, nas cidades de Juazeiro/BA e Petrolina/PE. Os dados compõem o sistema TABNET/DATASUS, segundo estado e município de residência. Foram notificados 306 casos de LV humana em Juazeiro/BA e 266 em Petrolina/PE com incidência média no período, respectivamente, de 7,77 e 4,53 casos/100.000 habitantes; em ambas as cidades, houve maior prevalência da LV no sexo masculino (Juazeiro/BA - 62,75% e Petrolina/PE – 64,66%); na faixa etária de 1 a 9 anos, respectivamente, 42,49% (Juazeiro/BA) e 48,12% (Petrolina/PE); seguida pela faixa dos 20 aos 59 anos, respectivamente, 39,87% (Juazeiro/BA) e 34,97% (Petrolina/PE). A letalidade média foi 12,25% em Juazeiro/BA e 4,54% em Petrolina/PE; quanto à coinfecção HIV/LV, foram identificados 3,92% de casos positivos em Juazeiro/BA e 14,29% em Petrolina/PE; contudo, respectivamente, 49,67% e 31,32% dos pacientes com LV não realizou teste para HIV. Os resultados apontam a manutenção do quantitativo de casos e altas taxas de incidência ao longo dos anos em ambas cidades, superiores às médias nacionais e regionais. Contudo, devido o preenchimento insatisfatório das informações, ficam comprometidas a análise da real proporção da repercussão da doença, bem como profilaxia e ações no controle dos agravos de notificação compulsória.
Luxação da articulação temporomandibular: uma revisão narrativa da etiologia ao tratamento conservador ou cirúrgico
Authors: Barbosa Lucas Bernardes da Silveira , Guimarães Júlia de Castro , Barbosa Renato
Published: March 2024

A articulação temporomandibular (ATM) é complexa e suscetível a várias condições, como disfunções, traumas e alterações degenerativas. A disfunção temporomandibular (DTM) afeta cerca de 10-15% da população. Luxações condilares podem ocorrer durante atividades normais, levando a complicações que impactam a qualidade de vida, como distúrbios do sono, baixa autoestima e depressão. Dessa forma, buscou-se apresentar as principais características da luxação da articulação temporomandibular, destacando os principais fatores etiológicos, achados clínicos e de imagem, diagnóstico, complicações e os tipos de tratamento. Realizada revisão narrativa, elaborada por meio da análise de fonte de evidências encontradas, sendo incluídos 30 artigos que tiveram seus dados criteriosamente interpretados e referenciados. Evidenciou-se a partir da referência selecionada que a luxação da ATM resulta de uma interação complexa de fatores, como trauma físico, anomalias anatômicas, hábitos parafuncionais e condições médicas associadas, manifestando-se com sintomas como dor, travamento mandibular e limitações funcionais. O diagnóstico combina anamnese, exame físico e exames de imagem para identificar alterações estruturais. As complicações incluem instabilidade articular, degeneração do disco e impactos psicossociais, requerendo uma abordagem terapêutica multidisciplinar que varia desde medidas conservadoras até intervenções cirúrgicas, enfatizando a importância de uma abordagem holística e personalizada para o tratamento eficaz da luxação da ATM. Sendo assim, a luxação da ATM é uma condição complexa que requer avaliação individualizada e tratamento interdisciplinar, visando aliviar os sintomas, restaurar a função mandibular e melhorar a qualidade de vida dos pacientes.
Impactos de longo prazo da cardite reumática em populações indígenas
Authors: Mendes Otávio de Almeida , Silva Rafael Fonseca Fernandes da , Souza Thiago Duarte da Costa Madureira , Ferreira João Pedro Gonçalves , Pedra Júlia Rodrigues Passos , Costa Mateus Magalhães Soares da , Guimarães Guilherme Soares Botelho
Published: March 2024

Introdução: A cardite reumática (CR) é uma complicação da febre reumática (FR), que ocorre por reação cruzada ao Streptococcos pyogenes. Dada à alta taxa de infecções em populações vulneráveis, o número absoluto de CR é aumentado em relação à média. Populações indígenas possuem maior dificuldade de acesso à saúde e estão mais propensas a desfechos negativos. Objetivos: Identificar as disparidades e impactos de longo prazo da CR em populações indígenas. Métodos: Trata-se de uma revisão integrativa de literatura, com inclusão de artigos entre 2018 e 2023, nas línguas portuguesa e inglesa. Foram encontrados 166 artigos e, após análise, foram selecionados 11 que atendiam aos critérios de inclusão. Resultados: A FR possui alta incidência dentre populações indígenas e baixo grau de diagnóstico precoce, com consequente evolução para CR com lesão valvar. Dificuldade no letramento em saúde e isolamento dificultam o rastreio, prevenção e tratamento da FR. A incidência de CR grave com indicação de substituição valvar é mais alta entre jovens indígenas. Possuir CR diminui a expectativa de vida e aumenta as chances de infecções oportunistas. Na Bacia Amazônica há alto índice de CR e grande prevalência de doença periodontal, o que aumenta as chances de endocardite bacteriana. Conclusão: Os estudos realizados em populações nativas na Oceania demonstram inequidade no acometimento em populações indígenas. No Brasil é possível perceber altos índices de CR, FR e endocardite, sobretudo em regiões com menor renda, realçando a necessidade de maior investigação a fim de reduzir os agravos da CR.
Macrossomia fetal e seu manejo na atenção primária, em gestantes sem critérios diagnósticos para diabetes mellitus gestacional pelo ministério da saúde: um relato de caso
Authors: Moscardini Pedro Marcos Coelho , Costa Geraldo Marques da , Souza Júnior David Barbosa de , Dias Maíra Figueiredo , Silva Danila Araújo e
Published: March 2024

Introdução: O objetivo deste trabalho é descrever um caso de macrossomia fetal descoberto no meio do terceiro trimestre, sem o diagnóstico de diabetes gestacional e associado a ganho de massa, através dos protocolos do Ministério da Saúde Brasileiro (MS). Tal relato visa demonstrar o desfecho e a linha de raciocínio utilizada. Justificativa: Devido à singularidade e falta de protocolos para manejo em atenção primária, fora decidido relatar tal caso. Como manejo: fora decido o controle glicêmico utilizando o protocolo de manejo da Diabetes Mellitus Gestacional (DMG), mudanças em hábito de vida, alteração alimentar, exercícios físicos regulares, além de encaminhamento para atenção terciária e nutricionista. Como resultado: fora obtido controle glicêmico, estabilização do ganho de massa e uma cesárea em 38 semanas. A conclusão é a necessidade dos médicos da atenção primária estarem atentos a tal quadro, oferecerem uma base para raciocínio clínico, diagnóstico junto a solicitação de alguns exames complementares, observando ganho de massa nesse grupo de paciente.
Suplementação de vitamina D na gestação
Authors: Cordeiro Amanda Castro , Barros Rosy Ane de Jesus Pereira Araújo
Published: March 2024

O presente trabalho aborda a crescente preocupação com a deficiência de vitamina D em gestantes e seu impacto na saúde materna e fetal. A vitamina D desempenha um papel crucial na regulação do cálcio e do fósforo, sendo essencial para o desenvolvimento fetal adequado. O problema da deficiência torna-se relevante, considerando as implicações para a saúde das gestantes e o potencial impacto nas gerações futuras. A revisão da literatura destaca a prevalência e os fatores de risco associados à deficiência de vitamina D em gestantes, bem como as consequências para a saúde materna e fetal. Além disso, são discutidas as diretrizes atuais de suplementação de vitamina D durante a gestação, junto com as evidências científicas sobre sua eficácia e segurança. A metodologia empregada envolve uma revisão e análise de estudos. Os resultados apresentam uma avaliação da eficácia da suplementação de vitamina D, destacando seu impacto nos níveis sanguíneos maternos e fetais, assim como os possíveis benefícios e riscos associados a essa prática. Este trabalho proporciona uma visão abrangente da problemática da deficiência de vitamina D em gestantes, oferecendo insights valiosos para profissionais de saúde e contribuindo para a compreensão dos impactos dessa condição na saúde materna e fetal.