bluuebunny/crossref_metadata_2025 huggingface dataset:
Cadet Magazines of the Beginning of the ХХ Century: Pedagogical Component
Authors:   Academy of Labor and Social Relation (Moscow), Bondarenko M. A.
Published: May 2022

The article presents material of the history of publishing periodicals in the Military Schools of the Russian Empire in the beginning of the ХХ century. Journals are considered as the capital and provincial cadet and junker schools, analyzes the participation of teaching staff of educational institutions in the preparation of publications. Attention is paid to the content of the periodic Cadet press and its role in the development of intelligent, creative and linguistic abilities of cadets, in establishing contact with graduates, in the development mutual respect of teachers and cadets, in formation of general cadet unity. The article concludes that the experience of military educational institutions on the organization of student printing can be used in modern pedagogical process.
Knowledge construction in the community of fishing women in the region of Guaraqueçaba – PR
Authors: Arns Elaine Mandelli , Strauhs Faimara do Rocio
Published: May 2022

In the knowledge dynamics, women's craft communities form a great ba: knowledge-sharing space. The objective of this article is to establish the dynamics of the process of knowledge construction and professional belonging in the Community of Practice of professional artisanal fisherwomen, in the region of Guaraqueçaba – PR – Brazil – in the light of the Actor-Network Theory, with an approximative approach to the SECI MODEL, a classic in the field of Knowledge Management. Applied, exploratory-descriptive and explanatory research was used as a methodology, with observant participation and mixed methods in the treatment of data, favoring the life stories, communal interactions and day-to-day activities of the involved fisherwomen. Findings: The network of human and non-human elements, the process of knowledge creation, was mapped establishing a comparison between the model proposed in this community and the SECI Model. It was confirmed that the SECI Model also applies outside formal organizations. In the analysis of communities of practice, the concept of communities of practice was expanded, in this context, to a community of women's craft. Research limitations: The shyness of the fisherwomen, the rainy weather not allowing for research or fieldwork, the slow pace of time on the way life passes in those communities; all these, require an adaptation from outsiders
Information reification: fake news about Covid-19 on the website of the Brazilian Departament of Health
Authors: Sousa Rodrigo Silva Caxias de , Valerim Patricia
Published: May 2022

This study analyzes fake news published on the website of the Brazilian Department of Health about COVID-19 in 2020. It argues that different forms of disinformation were constituted into reified communicative processes. The study emphasizes the emergence of a disinformation production circuit whose logic is the trivialization of informational practices manifested through fake news. The methodology applied here is of an exploratory-descriptive work with a qualitative approach and content analysis. The analyses prompted the emergence of six categories obtained a posteriori: main theme, language, elements that make up the news, rhetorical devices, devices for attributing credibility to the news, and fact-checking procedures. It can be affirmed that the news articles found are based on instrumental compositions that articulate themes related to the pandemic in a simplistic way, with language that disregards grammar norms, and resorting to the combined use of several elements, specially through text and image, and of different rhetorical devices – with the recurrent use of authorities to attribute credibility to the news, and the presence of inconsistencies in fact-checking procedures by Department of Health. Finally, it can be affirmed that the fact-checking carried out by the Brazilian Department of Health had as reference the politicization of the disease in face of the tension between science, politics and the market, which compromises the fight against this health crisis and corroborates the instrumental logic of the information circulating on the web
Genealogia de um imaginário: Literatura, Ciência e o Antropoceno
Authors: Crippa Giulia , De Almeida Marco Antonio
Published: May 2022

O artigo traça uma genealogia do imaginário antropocênico dos últimos dois séculos, através de obras literárias, em busca de tropos e formas culturais que moldaram a percepção pública sobre o assunto. Parte da hipótese de que estes imaginários compartilhados dizem respeito tanto às lentes usadas para interpretar os fenômenos e ações atuais, considerando as interpretações do passado, como para a definição de horizontes de possibilidade. Seleciona e discute autores pioneiros da ficção científica (Verne, Wells), autores da década de 60 até chegar à produção literária contemporânea. Conclui que a capacidade da narrativa e da imaginação artística destas obras permite estimular experiências emocionais, estéticas e de vida que possibilitam uma melhor compreensão do Antropoceno e suas implicações
Quando a Fake News acelera o Antropoceno: O caso da Floresta Amazônica (2018-2021)
Authors: Pinheiro Daniel Calbino
Published: May 2022

Os últimos quatros anos, no Brasil, foram marcados por profundos retrocessos nas políticas ambientais. Um elemento agravante foi a propagação de informações falsas que visava desinformar sobre os impactos diretos da ação humana na natureza. Nesse contexto, o objetivo geral do trabalho consistiu em compreender de que forma as Fake News, ao negarem as interferências humanas no meio ambiente, tem contribuído para o aceleramento desse processo. Para tal, foi utilizado a metodologia de pesquisa documental e bibliográfica, com o uso de análise de conteúdo sobre as narrativas proferidas pelo presidente da república, entre os anos de 2018 e 2021. Os resultados apontaram que as mensagens anticiência e negacionistas do presidente fomentaram a sustentação política para o esvaziamento do monitoramento e fiscalização no contexto ambiental, bem como para os sucessivos aumentos das queimadas e desmatamentos na Floresta Amazônica. Enquanto conclusões, o trabalho coloca para a área a importância de se considerar os impactos das notícias falsas nas tentativas de se reduzir o Antropoceno, ressaltando, contudo, que a sua dinâmica tem se mostrado mais complexa do que a simples ênfase na carência de alfabetização científica e ambiental
O papel das ecoinovações na transição para uma Economia Circular
Authors: Motta Wladmir Henriques
Published: May 2022

Nos últimos anos, as abordagens sobre a relação entre meio ambiente, sistema econômico e sociedade vêm ganhando força nos debates nacionais e internacionais devido à constante deterioração das condições de vida no planeta, principalmente por meio da aceleração do esgotamento dos recursos naturais e a geração exacerbada de resíduos. O atual modelo econômico baseado na superprodução e superconsumo levou o mundo à crise ecológica e esse “velho” modelo deve ser modificado ou adaptado a uma realidade de crise. Assim, rever as práticas organizacionais é hoje um elemento crucial para divulgar as áreas onde os esforços inovadores devem se concentrar. A economia circular surge como alternativa à abordagem linear tradicional. O desafio desta proposta é desenvolver uma abordagem inovadora para superar o atual trade-off entre o modelo de crescimento econômico incessante e o Antropoceno. Essas inovações devem enfrentar os problemas ambientais vivenciados, constituindo-se, portanto, em ecoinovações, um tipo de inovação que pode promover a redução do consumo de recursos naturais, emissão de gases de efeito estufa e geração de resíduos, entre outros desafios ambientais. Nesse contexto, indaga-se, como as ecoinovações podem contribuir para construir a necessária abordagem circular? O presente estudo visa lançar luz a essa discussão por meio de uma revisão de literatura analisando o importante papel da economia circular e suas relações com as ecoinovações
Crescimento demoeconômico no Antropoceno e negacionismo demográfico
Authors: Alves José Eustáquio Diniz
Published: May 2022

O mundo experimentou, nos últimos 250 anos, um crescimento econômico e demográfico, de tal ordem, que degradou a maioria dos ecossistemas do Planeta, provocou a perda de biodiversidade e desestabilizou o clima que havia apresentado uma impressionante estabilidade no Holoceno. Assim, gestou-se uma nova Era geológica, o Antropoceno, época em que as atividades antrópicas se constituem em uma força tão poderosa que tem sido capaz de sobrepassar a capacidade de carga da Terra. O objetivo deste artigo é mostrar como o impacto do crescimento econômico e demográfico influiu na sobrecarga ambiental e na elevação das emissões de carbono, que são vetores inequívocos do agravamento da crise climática e ambiental. Para tanto será utilizado, por um lado, a metodologia que relaciona a Pegada Ecológica e a Biocapacidade da Terra para mensurar, tanto o déficit ecológico global, quanto o déficit por categorias de renda. Por outro lado, serão avaliadas as correlações entre as emissões de CO2, a temperatura global e o crescimento da economia e da população. Ao contrário do que opinam os céticos e negacionistas, o artigo reforça o entendimento de que o aumento das atividades humanas sobre o meio ambiente, principalmente nos últimos 70 anos, tem rompido os limites das fronteiras planetárias. E, embora o aumento do volume global da produção de bens e serviços deva ser considerado o principal fator desestabilizador do Sistema Terra, não se pode desconsiderar a contribuição do crescimento demográfico para a ampliação do déficit ecológico global
Narava v izbrani Aškerčevi poeziji do leta 1900
Authors: Rizmal Lovro
Published: May 2022

Članek preuči motive iz narave v pesmih Antona Aškerca (1856–1912) do leta 1900. Pesniku je bila njegova rojstna pokrajina Štajerska vir motivov tako iz žive kot nežive narave, v veliki meri je v svojih pesmih upodobil tudi tuja okolja in eksotično naravo, tipično za njih. Pomembno funkcijo ima narava v ustvarjanju tesnobnega in grozljivega razpoloženja v literarni zvrsti baladi, kjer Aškerc upesni tudi fantastične pojave, a na način, da jih lahko pojasnimo tudi kot psihološke. Naravo Aškerc opazi v povezavi s socialno in nacionalno problematiko, uvidi jo tudi kot panteistično enost vsega stvarstva in v obliki ženske boginje. Tolikšna raznolikost obravnavanih prvin Aškerčevih pesmi pove, da je pesnik z njimi prešel takratno obrobnost svoje rojstne pokrajine in postal del središča slovenske kulture ter pesnik nacionalnega kanona.
Tri tipa ekranizacije književnih djela na primjeru ukrajinske književnosti
Authors: Pavlešen Dariya , Kliček Domagoj
Published: May 2022

Cilj je ovog članka prikazati na koji su način određena ideja, aspekt ili koncept preneseni na filmsko platno uz pomoć različitih modela adaptacije književnog teksta. Idealizacija, estetizacija i transformacija, po mišljenju autora, tri su pristupa s pomoću kojih su jedan klasičan tekst ukrajinske književnosti (Kajdaševa simˮja, Nečuj-Levyc'kyj, 1879.), dramsko djelo (Dykyj Angel, Kolomijec’, 1978.) te jedan suvremeni roman (Felix Avstrija, S. Andruhovyč, 2014.) adaptirani u film.
Передача единиц шотландского диалекта в переводах Роберта Бернса на русский и словенский языки
Authors: Kaloh Vid Natalia , Koletnik Mihaela
Published: May 2022

Перевод диалектных выражений и диалектально маркированных слов является одной из самых сложных задач стоящих перед художественным переводчиком. Замена таких выражений литературными означает вмешательство в стилистические особенности оригинала, при этом об использовании диалекта языка перевода часто не может быть и речи из-за пестроты и разнообразия диалектов, особенно в Словении. Материалом исследования послужили переводы известного шотландского поэта Роберта Бернса на русский и словенский языки. Автором русского перевода является Самуэль Маршак, а словенский перевод подготовил Янез Менарт. Целью исследования является анализ способов передачи разговорного шотландского языка, который очень часто встречается в стихах Бернса, в русском и словенском переводах. Результаты исследования показали, что характерные для Бернса диалектные выражения Маршак заменил литературными и таким образом диалект в русском переводе был полностью утрачено. Менарт подошел к данной переводческой задачи по-другому и в его переводах прослеживается много диалектных и разговорных выражений.
​​Comparative Evaluation of Hatching Traits in Four Phenotypes of Naked Neck Chicken
Authors: Shafiq M. , Khan M.T. , Rauf M. , Raziq F. , Bughio E. , Gondal M.A. , Jalees M.M. , Liaqat S.
Published: May 2022

Background: In Pakistan, the naked neck chickens are characterized on the base of plumage colors such as black, white black, light brown and dark brown. There is scanty of information on hatching traits in different phenotypes of naked neck chicken. The current study aimed to investigate and compare the hatching traits in four phenotypes of naked neck chicken (black, white black, light brown and dark brown). Methods: In total, 300 females (20 weeks old) comprising four plumage colors (black, white black, light brown and dark brown), 75 from each, were randomly assigned to 20 replicates (15/replicate) under a completely randomized design (CRD). Number of settable eggs, fertility, hatch of fertile, hatchability, embryonic mortality and chick quality parameters were evaluated. Result: The results showed higher settable eggs, fertility and hatchability in black, dark brown and light brown phenotypes than that of the white black whereas better hatch of fertile and reduced embryonic mortality were recorded in black and dark brown phenotypes as compared to white black. Better chick quality was observed in dark brown phenotype followed by light brown, black and then white black. Phenotypes other than white black had better hatching performance, hence could be used to revive backyard poultry farming.
The Analysis of Genetic Variation in the Mitochondrial ND6 Gene and its Application for the Identification of Indonesian Catfish Species
Authors: Widayanti Rini , Ibrahim Alek , Maulana Muhammad Hesham , Sakti Korniawan Eko , Arifah Danastri Hanida Nur , Pakpahan Suhendra
Published: May 2022

Background: Catfish is a freshwater and saltwater fish type with a wide distribution throughout the Indonesian archipelago. This study was conducted to analyze Indonesian catfish’s genetic diversity and evolutionary relationships based on the mitochondrial ND6 gene. Methods: Twenty-eight catfish samples were collected from nine rivers and one ocean in seven provinces of Indonesia. The MT-ND6 gene was amplified by using a set of primers (BaungND6F and BaungND6R). The MEGA X software was used to examine the MT-ND6 sequences for genetic variation and phylogenetic relation between Indonesian catfish populations. Result: There were 167 nucleotide site variations and thirty-two amino acid variations in the MT-ND6 gene. The genetic difference among populations ranges from 0.9 to 25% and the average evolutionary divergence in the overall populations was 14%, with catfish BB and PM having the closest genetic distance, while the farthest is BF to MP and BF to MS. In conclusion, the phylogenetic tree indicated that there were four distinct catfish clades in this study: MP, MS, KR, PM, BB and KS had been grouped with Hemibagrus nemurus (Bagridae family), EM had been grouped with Mystus vittatus (Bagridae family), BSBJ had been grouped with Pangasius pangasius (Pangasiidae family) and PD and BF had been grouped with Netuma thalassina (Ariidae family).
Evaluation of head cabbage varieties and botanicals for diamondback moth management in east Shewa
Authors: Begna Feyisa
Published: May 2022

Cabbage is the second most important vegetable crop in Ethiopia. Many insect pest species belonging to 16 families have been recorded on cabbages. The objective of this study was to determine the influence of head cabbage varieties and botanicals against DBM on head cabbage. The experiment was conducted using irrigation at Adami Tulu Agricultural Research Center (ATARC) during the 2020 cropping season. The head cabbage Glorai, Victoria, K500, Bandug F1and ThomaF1 varieties were used for this experiment. Treatments were arranged in a randomized complete block design (RCBD) with three replications. For DBM management two locally available botanicals and fastac chemicals were sprayed continuously for four weeks and an untreated plot was included for comparison. Throughout the growing season fastac significantly reduced the DBM larvae and pupae population, followed by neem seed and garlic cloves. Highly significant differences among the treatments were observed after the application of botanicals and chemicals on DBM larvae and pupae mortality rate in all of the treatments, but non-significant differences were observed among the head cabbage varieties. 
Keywords: Botanical; garlic; fastac; head cabbage; neem; Plutella xylostella.
Unleash the untaught mathematics competencies through online, shareable and offline video lectures
Authors: Batilantes Sherwin
Published: May 2022

The study aimed to determine the benefits of project online, shareable and offline (OSO) video lectures to seventh-grade students during flipped classroom to resolve untaught mathematics competencies before the school year ended. The study employed the experimental research design, and three groups were randomly selected from the seventh-grade population as respondents. These three groups underwent pre-test and post-test during and after the intervention using the verified and quality-assured test questionnaires by an expert panel of evaluators. The study’s findings revealed that learners’ test scores differed significantly among the three groups based on one-way analysis of variance. However, the Tukey post-hoc test showed that the flipped online group differed substantially from the flipped shareable and offline groups. Consequently, project OSO was considered a valuable resource in the flipped classroom and is highly recommended for instructing learners when the teacher is out due to school-related functions among the three video lectures’ platforms.
Keywords: Ancillary service, flipped classroom, mathematics education, project OSO, unattained competencies;
Precisión diagnóstica de los Scores Brighton y Coast para la admisión al hospital de emergencias pediátricas en el periodo 2018
Authors:   , Pantigozo-Rimachi Andrea , Murillo Díaz Giuliana Katherine
Published: May 2022

Objetivo: Identificar las características de nuestra población y la precisión diagnóstica de los scores Brighton y COAST para predecir la admisión hospitalaria en el servicio de Emergencia de un hospital pediátrico Materiales y métodos: Estudio de cohorte tipo retrospectivo en población pediátrica de 1 mes a 17 años, que acudieron al servicio de emergencia del Hospital de Emergencias Pediátricas en los meses de febrero y agosto del 2018 en Lima, Perú. Se recabó datos para los scores Brighton y COAST a través de revisión de historias clínicas, las cuales se verificaron hasta el momento de admisión hospitalaria o alta del servicio de emergencia del paciente. Se calculó sensibilidad, especificidad, valores predictivos positivos y negativos, cociente de verosimilitud y el área bajo la curva (AUC). Resultados: Con una población de 822 pacientes. Se admitieron al servicio de hospitalización 86 pacientes y 736 fueron no hospitalizados. Con dichos datos se obtuvo para los scores Brighton y COAST con un punto de corte ≥3 una sensibilidad de 69,8% y 63,3%, respectivamente y una especificidad de 87,8 %y 87,6% para ambos scores. Así, como una AUC de 0,82 para Brighton y 0,80 para COAST. Conclusiones: Los puntajes ≥3 para los scores Brighton y COAST es específico y poco sensible para predecir admisión hospitalaria. No obstante, el valor predictivo negativo de estos scores es alto (mayor a 90%), por lo cual el número de pacientes con puntaje menor a 3 que requieran hospitalización será mínimo.
THE RELATIONSHIP BETWEEN THE CHARACTERISTICS OF THE CHOICE OF TRANSPORTATION MODES IN THE CITY OF WEST JAKARTA DURING THE COVID-19 PANDEMIC
Authors: Reizsky Reynaldy  , Martina Kasikoen Ken , Listya Cahya Darmawan , Novetrishka Putri Mega
Published: May 2022

The Covid-19 pandemic that has hit the world in recent years has changed the habit of life of many people, with no exception to the West Jakarta City Administration citizen.. Various citizen activities started to adjust to the current living circumstances. This study was conducted to determine the relationship between the characteristics of mode selection and the usage of types of transportation modes in the Administrative City of West Jakarta during the Covid-19 Pandemic. This research data was obtained through an online-based survey regarding the characteristics of the mode selection of citizens of the West Jakarta Administrative City during the Covid-19 Pandemic. The resulting data is processed using statistical correlation analysis based on the chi-square test. The results of the analysis show that the highest proportion of the use of this type of transportation mode is in the Administrative City of West Jakarta during the Covid-19 pandemic, namely 68.5% are private vehicle users and 31.5% are public transport users. which are gender factors, vehicle ownership, SIM ownership, frequency of daily activities, distance travelled, the distance of public transportation facilities from home, distance of public transportation facilities from the activities place, travel time during a pandemic, waiting time for transportation modes, and travel costs have a relationship with the usage of this type of transportation in West Jakarta Administrative City During the Covid-19 Pandemic
Spatial and temporal variability of the Alligatorweed pathogen, Alternaria alternantherae, in Louisiana
Authors: Harms Nathan , Shearer Judy
Published: May 2022

Alligatorweed leaf spot is a disease of invasive Alternanthera philoxeroides (Alligatorweed) in the southern US, caused by Alternaria alternantherae. However, little is known about when or where this pathogen naturally occurs. To better understand this species’ life history, we examined temporal (every 2–3 weeks) and spatial (latitudinal) patterns of A. alternantherae occurrence at sites in Louisiana for 2 y. Pathogen presence reflected clear within-year temporal and spatial patterns. Overall, the percentage of leaves infected with A. alternantherae was low during spring each year (0–20% infected) but increased throughout summer (maximum of 50% infected), and plants in northern sites had lower frequency of infection relative to southern sites until later in the year (late summer/early fall) but only in 1 of the 2 years of our study. The mean proportion of leaves infected with A. alternantherae declined with latitude both years (P = 0.01) and variability increased with latitude (P = 0.04), a pattern suggestive of range limitation in northern areas. We estimate a northern distributional limit of 34°N for A. alternantherae in Louisiana, but Alligatorweed occurs farther north. Although we did not directly examine disease impacts to Alligatorweed during the study, they may be greatest in southern areas, where the pathogen is more common early and throughout the growing season, and thus may be less likely to provide control in northern infestations of the invasive Alligatorweed.
Body Image and Health-related Behaviors Among Fitspirit Participants
Authors: Bordeleau Manon , Gilbert Jo-Anne , Alméras Natalie , Monthuy-Blanc Johana , Gagnon Joël , Mathieu Marie-Ève , Drapeau Vicky
Published: May 2022

Background: Body image variables such as body size perception (BSP) and body size dissatisfaction (BSD) can influence health-related behaviors. However, few studies have investigated these body image variables in adolescent girls participating in a physical activity intervention. Therefore, the study objectives were to examine the 1) associations between health-related behaviors (physical activity, screen time, eating habits and sleep duration) and BSP and BSD among girls participating in FitSpirit, a physical activity intervention for girls; and 2) influence of weight control practices on the association between health-related behaviors and BSP and BSD.Methods: This cross-sectional study used a sample of 545 adolescent girls (mean age: 15.0±1.5 years) from 240 schools. Body mass index, health-related behaviors, perceived actual body size and desired body size variables were self-reported and collected via an online questionnaire at the end of the FitSpirit intervention. A negative BSP score [perceived actual body size – calculated BMI z-score] indicates an underestimation of body size. A positive BSD score [perceived actual body size – desired body size] indicates a desire to reduce body size. A multiple linear regression analysis examined the effects of age, zBMI and health behaviors on BSP and BSD. A second multiple linear regression analysis examined the independent associations between BSP and BSD by weight control practice. The linear relationships between BSP and BSD were evaluated with Pearson’s correlations. Results: Underestimation and dissatisfaction of body size are more prevalent in participants living with overweight/obesity. Screen-time and sleep duration were independently associated with BSP score (Beta=0.02; P<0.05 and Beta=-0.07; P<0.05, respectively), whereas only screen time was associated with BSD score (Beta=0.07; P<0.001). Physical activity was independently associated with BSP score only in participants trying to control their weight (Beta=-0.18; P<0.05).Conclusions: Body size overestimation and dissatisfaction are associated with health-related behaviors, specifically with more screen-time and less optimal sleeping habits. Physical activity level does not appear to be associated with body image in girls engaged in a physical activity intervention and who want to lose or gain weight. Health promotion interventions could include screen-time and sleep components as they may influence body image.
Understanding the role of complexity in bottom-up healthcare innovations: a multiple case study using the NASSS-CAT tool
Authors: Tang Ulla Hellstrand , Smith Frida , Karilampi Ulla , Gremyr Andreas
Published: May 2022

Background: New digital technology presents new challenges to healthcare on multiple levels. There are calls for further research embracing the complex factors related to digital innovations in complex healthcare settings in order to bridge the gap in moving from linear, logistic research to embracing and testing the concept of complexity. The aim was to explore the role of complexity in bottom-up innovations within public healthcare in a Swedish region.Methods: Four bottom-up innovators identified complexities in their innovations using the NASSS framework with its seven domains (condition, technology, value proposition, adopters, organisations, wider system and embedding, and adaption over time); the related Complexity Assessment Tool (CAT); and Constant Comparative Analysis (CCA), in collaboration with the Innovation Platform in the Region Västra Götaland in Sweden.Results: An initiated understanding of the complexity relating to the illness addressed in the innovation is of great importance as a starting point. Value proposition needs to be clearly described early in the process, to enable understanding costs and outcome. If regional support only allows regional use, not national spread, there will be no dissemination and the innovations risk failing after the initial project phase.Conclusions: Using a validated tool early in the process of innovation is helpful but requires profound knowledge about complexity and the intended system for implementation. Finding and defining complexity does not solve the issues, but will increase possibilities of success if the right competence is available for support. Trial registration: n/a
Early intubation and patient-centered outcomes in septic shock: a secondary analysis of a prospective multicenter study
Authors: Artigas Ricard Mellado , Ferrando Carlos , Martino Fréderic , Delbove Agathe , Ferreyro Bruno L , Darreau Cedric , Jacquier Sophie , Brochard Laurent , Lerolle Nicolas
Published: May 2022

Purpose: Despite the benefits of mechanical ventilation, its use in critically ill patients is associated with complications and had led to the growth of non-invasive techniques. We assessed the effect of early intubation (first 8 hours after vasopressor start) in septic shock patients, as compared to non-early-intubated subjects (unexposed), regarding in-hospital mortality, intensive care and hospital length of stay. Methods: Secondary analysis of a multicenter prospective study. To adjust for baseline differences in potential confounders, propensity score matching was carried out. In-hospital mortality was analyzed in a time-to-event fashion while length of stay was assessed as a median difference using bootstrapping. Results: 735 patients (137 intubated in the first 8 hours) were evaluated. Propensity score matching identified 78 pairs with similar severity and characteristics on admission. Intubation was used in all patients in the early intubation group and in 27 (35%) subjects beyond 8 hours in the unexposed group. Mortality occurred in 35 (45%) and in 26 (33%) subjects in the early intubation and unexposed groups (hazard ratio 1.44 95% CI 0.86-2.39, p=0.16). ICU and hospital length of stay were not different among groups [9 vs 5 (95% CI 1 to 7) and 14 vs 16 (95% CI -7 to 8) days]. All sensitivity analyses confirmed the robustness of our findings.Conclusions: An early approach to invasive mechanical ventilation did not improve outcomes in this matched cohort of patients. The limited number of patients included in these analyses out the total number included in the study may limit generalizability of these findings. Trial registration: NCT02780466. Registered on May 19th, 2016.
Robust Laser Beam Attenuation Characteristics Using Novel Polymeric Nanocomposite
Authors: Saeed Chro , Qader Abdulqader Abdullah , Aziz shujahadeen Bakr
Published: May 2022

Novel polymer nanocomposites polyethylene oxide (PEO) with lead oxide (Pb3O4) semiconductor nanoparticles were prepared using solution casting technique and investigated experimentally. A robust laser power attenuation for semiconductor laser and green laser were obtained for different concentrations (0, 3, 6, and 9) wt% of Pb3O4 in the polymer matrix (PEO), and different angle of laser beam incidence. Polymer nanocomposites have applications in electromagnetic absorption shields, cut-off laser filters, and photo-electronics.
Development of new Copper-64 labeled Rhodamine: A potential PET myocardial perfusion imaging agent
Authors: aljammaz I. , Al-Hokbany N. , Al-Otaibi B. , Al-Malki Y. , AlJammaz B. , Okarvi S. M.
Published: May 2022

Background
Myocardial perfusion imaging (MPI) is one of the most commonly performed investigations in nuclear medicine procedures. Due to the longer half-life of the emerging positron emitter copper-64 and its availability from low energy cyclotron, together with its well-known coordination chemistry, we have synthesized 64Cu-labeled NOTA- and 64Cu-NOTAM-rhodamine conjugates as potential cardiac imaging agents using PET.
Results
64Cu-NOTA- and 64Cu-NOTAM-rhodamine conjugates were synthesized using a straightforward and one-step simple reaction. Radiochemical yields were greater than 97% (decay corrected), with a total synthesis time of less than 25 min. Radiochemical purities were always greater than 98% as assessed by TLC and HPLC. These synthetic approaches hold considerable promise as a simple method for 64Cu-rhodamine conjugates synthesis, with high radiochemical yield and purity. Biodistribution studies in normal Fischer rats at 60 min post-injection, demonstrated significant heart uptake and a good biodistribution profile for both the radioconjugates. However, the 64Cu-NOTAM-rhodamine conjugate has shown more heart uptake (~ 10% ID/g) over the 64Cu-NOTA-rhodamine conjugate (5.6% ID/g).
Conclusions
These results demonstrate that these radioconjugates may be useful probes for the PET evaluation of MPI.
Deep reinforcement learning identifies personalized intermittent androgen deprivation therapy for prostate cancer
Authors: Lu Yitao , Chu Qian , Li Zhen , Wang Mengdi , Zhang Qingpeng
Published: May 2022

The evolution of drug resistance leads to treatment failure and tumor progression. Intermittent androgen deprivation therapy (IADT) helps responsive cancer cells compete with resistant cancer cells in intratumoral competition. However, conventional IADT is population-based and ignores the heterogeneous phenotypes of individual patients. To address this challenge, we developed a time-varied, mixed-effect, and generative Lotka-Volterra (tM-GLV) model to account for the heterogeneity of the evolution mechanism and the pharmacokinetics of individual patients. Then, we proposed a reinforcement learningenabled individualized IADT framework, namely, I2ADT, to learn the patient-specific tumor dynamics and derive the optimal drug administration policy. Experiments with clinical trial data demonstrated that the proposed I2ADT can significantly prolong the time to progression of prostate cancer patients with reduced cumulative drug dosage. This research elucidates the application of reinforcement learning techniques to identify personalized adaptive cancer therapy.
Temporal and Spatial Distribution Characteristics and Source Analysis of Dissolved Organic Nitrogen in the Surface Sediment of the Caohai Lake, Southwest China
Authors: Yan Xinting , Liao Jiahao , Cao Xingxing , Han Zhiwei
Published: May 2022

The Caohai is a typical natural lake-type karst plateau wetland, which is sensitive to environmental changes, and the release of dissolved organic nitrogen (DON) in the sediment is a potential factor of nitrogen pollution in the lake. Therefore, this study aimed to reveal the temporal and spatial distribution characteristics and source analysis of DON in karst lake sediments. Surface sediment samples were collected from the Caohai Lake in southwest China, and the sample locations were distributed across almost the entire wetland area during both the wet and dry seasons. The DON content and fluorescence spectroscopy were determined and analysed using a three-dimensional fluorescence-parallel factor analysis (3DEEM-PARAFAC) model. The mean DON content in the sediment during the dry season (67.79 mg/kg) was higher than in the wet season (28.57 mg/kg). There were four fluorescent components of DON in the sediment: C1 (tyrosine-like protein), C2 (terrestrial humus), C3 (tryptophan-like protein), and C4 (terrestrial humus). The maximum fluorescence intensity of each component in both seasons showed the trend of C2 > C1 > C3 > C4. The DON in the surface sediment of the Caohai Lake was influenced by terrestrial sources and biological activities. These findings help reveal the circulation mechanism of endogenous nitrogen in the lake and provide theoretical support for the prevention and control of nitrogen pollution in the Caohai Lake.
Calcium poisoning mechanism on the selective catalytic reduction of NOx by ammonia over the γ-Fe2O3 (001) surface
Authors: Geng Xuan , Xie Chaoyue , Zhu Baozhong , Chen Jiuyu , Sun Yunlan , Xu Minggao
Published: May 2022

γ-Fe2O3 has an excellent low-temperature SCR deNOx performance, but its resistance to alkaline earth metal calcium (Ca) is poor. In particular, the detail mechanism of Ca poisoning on the γ-Fe2O3 catalyst at the atomic level is not clear. Hence, the density functional theory (DFT) method was used in this research to investigate the influence mechanism of Ca poisoning on the NH3-SCR over the γ-Fe2O3 catalyst surface. The findings reveal that NH3, NO, and O2 molecules can bind to the γ-Fe2O3 (001) surface to generate coordinated ammonia, monodentate nitroso, and adsorption oxygen species, respectively. The main active site is Fe1-top. For the γ-Fe2O3 with Ca poisoning, the Ca atom has a higher adsorption energy on the surface of γ-Fe2O3 (001), which covers the catalyst surface and reduces the active sites. The presence of Ca atom decreases the adsorption performance of NH3, while slightly improves the NO and O2 adsorption. In particular, The Ca atom restrains the NH3 activation and NH2 formation, which is detrimental to the NH3-SCR process.
Does Environmental, Social and Governance Performance Score Mitigate Earnings Management Practices ? Evidence from the US Commercial Banks.
Authors: Kolsi Mohamed Chakib , Al-Hiyari Ahmad , Hussainey Khaled
Published: May 2022

Environmental, social and governance (ESG) performance has attracted debates of regulatory bodies and the academic community. Previous studies highlighted the relationship between corporate social responsibility (CSR) disclosure index and earnings management (EM) for non-financial firms. In this paper, we examine the relationship between the ESG performance and EM practices for a sample of US commercial banks over the period 2010–2019. We use two proxies for earnings management: abnormal loan loss provisions (ALLP) and EM to avoid losses (SPOS). Consistent with the transparent financial reporting hypothesis, we find that banks reporting higher ESG performance are less likely engaged in income-increasing practice through (ALLP). However, no evidence supports that ESG score mitigates EM through loss avoidance. Furthermore, we disaggregate the ESG score into its main three components: environmental, social, and governance. Our findings show that the governance pillar effectively mitigates earnings management (EM) practice under its two proxies. Furthermore, the social pillar also seems to be an efficient constraint of banks’ EM through income increasing abnormal loan loss provisions and loss avoidance activity. However, no supporting evidence of a mitigating role for the environmental pillar is provided. Taken together, our results show that, except the environmental pillar, ESG performance score acts as an efficient mitigating tool for EM practices. Our findings provide a better understanding of banks earnings management practices. Our findings are helpful for managers, regulators, and banks’ stakeholders.
The clinical outcomes and complications of combined fixation with cannulated screws and the modified Pyrford technique for the treatment of transverse patellar fractures: a case series study
Authors: Li Yihan , Tian Qingxian , Leng Kunpeng , Guo Meng
Published: May 2022

Background: Transverse patellar fractures can be fixed using various techniques. The purpose of the current study was to assess the clinical outcomes and complications rate of a combined fixation technique using cannulated screws and the modified Pyrford technique with non-absorbable polyester sutures.Methods and Patients: Between January 2015 and February 2021, 26 transverse patellar fractures were fixed with this combined technique. Pre-operative data were collected from patients with transverse patellar fractures and the patients were followed up for at least 12 months. At each follow-up visit, plain radiographs were taken. At the 12-month post-operative follow-up, range of motion of the affected knee joint and clinical outcomes, as evaluated by the Bostman scoring system, were recorded.Results: The average Bostman score at the 12-month post-operative follow-up was 28.3±1.5. Further, the average extension and flexion of the knee joint were 1.2±2.1 and 125.6±6.7 degrees, respectively. One patient experienced delayed bone union and one experienced superficial wound infection. There were no other post-operative complications. One patient required removal of the device for social-psychological reasons. Conclusions: The combined fixation technique with cannulated screws and the modified Pyrford technique with suture materials produced excellent clinical outcomes and a low rate of complications in the treatment of transverse patellar fractures.
Evaluation of landslide susceptibility based on VW-AHP-IV model: a case of Pengyang County, Ningxia, China
Authors: Li Minghong , MA Chuanming , Qiu Yang , Xiong Hanxiang , Zhang Zechen
Published: May 2022

Landslide is one of the most common and severe geological disasters, which significantly endangers people's lives and properties. Therefore, the evaluation of landslide susceptibility in a specific area is important for disaster control and mitigation. This paper selected Pengyang County as the study area. It divided the indicator state levels, and further assigned a score for each indicator according to the related information values (IV) based on the analysis of graded area ratio and landslide occurrence frequency distribution. Because the solo analytical hierarchy process (AHP) method always causes large errors during the weight determination, a variable-weight based weighted information value (VW-AHP-IV) model was applied in this paper for landslide susceptibility evaluation. The study area was classified into four grades by the natural breakpoint method: high susceptibility area (11.80%), medium susceptibility area (29.23%), low susceptibility area (42.45%) and very low susceptibility area (16.52%). In addition, this paper also discussed the influences of precipitation and human activities. According to the evaluation results and discussion, the study area was classified into three prevention and control areas: focus prevention and control area, sub-focus prevention and control area, and general prevention and control area. For each area, the corresponding prevention and control suggestions were proposed in order to reduce the occurrence of landslide disasters.
Short-term effects of air pollutants and meteorological factors on daily outpatient visits for urticaria in Shijiazhuang, Hebei Province, China
Authors: Nie Yaxiong , Liu Lijuan , Xue Shilin , Yan Lina , Ma Ning , Liu Xuehui , Liu Ran , Wang Xue , Wang Yameng , Zhang Xinzhu , Zhang Xiaolin
Published: May 2022

Objective: The associations of air pollutants and meteorological factors with the outpatient visits of urticaria remain poorly studied. This study aimed to assess the short-term effects of air pollutants and meteorological factors on daily outpatient visits for urticaria in Shijiazhuang, China, during 2014-2019.Methods: Daily recordings of air pollutants concentrations, meteorological data, and the outpatient visits data for urticaria were collected during the 6 years. Descriptive research methods were used to describe the distribution characteristics and demographic features of urticaria. A combination of the generalized linear regression model (GLM) and distribution lag nonlinear model (DLNM) was used to evaluate the lag effect of environmental factors on daily outpatient visits for urticaria. Results: The dose-response relationship between daily urticaria visits and CO, NO2, O3, temperature, and relative humidity was nonlinear. High concentrations of CO, NO2, O3, and high temperatures increased the risk of urticaria outpatient visits. The maximum cumulative effect of high concentrations of CO, NO2, and O3 was lag 0-14 days (CO: RR = 1.10, 95%CI: 1.06, 1.31; NO2: RR = 1.09, 95%CI: 1.01, 1.08; O3: RR = 1.16, 95%CI: 1.08, 1.25), and high temperatures was lag 0-7 days (RR = 1.27, 95%CI: 1.14, 1.41). Low concentrations of NO2, O3, and high humidity, on the other hand, act as protective factors for the urticaria outpatient. The maximum cumulative effect of low concentrations of NO2 was the 0-day lag (RR = 0.97, 95%CI: 0.95, 0.99), O3 was lag 0-5 days (RR = 0.94, 95%CI: 0.88, 0.99), and high humidity was lag 0-10 days (RR = 0.93, 95%CI: 0.89, 0.98).Conclusions: In conclusion, we found that the development of urticaria in Shijiazhuang has a distinct seasonal and cyclical nature. Air pollutants and meteorological factors had varying degrees of influence on the risk of urticaria outpatient visits.
Genetic diversity, reassortment, and recombination of mammalian orthoreoviruses from Japanese porcine fecal samples
Authors: Fukase Yuka , Minami-Fukuda Fujiko , Masuda Tsuneyuki , Oi Toru , Takemae Hitoshi , Ishida Hiroho , Murakami Hironobu , Aihara Naoyuki , Shiga Takanori , Kamiie Junichi , Furuya Tetsuya , Mizutani Tetsuya , Oba Mami , Nagai Makoto
Published: May 2022

Mammalian orthoreovirus (MRV) is a non-enveloped double-stranded RNA virus with a broad host range. MRVs are prevalent worldwide and have been isolated from various hosts, including humans, dogs, cats, wild boars, sewage, and pigs, in Japan. However, Japanese porcine MRV has not been genetically characterized yet. While investigating porcine enteric viruses including MRV, five MRVs were isolated from the feces of Japanese pigs using the MA104 cell culture. Genetic analysis of the S1 gene revealed that the Japanese porcine MRV strain isolates could be classified as MRV-2 and MRV-3. Whole genome analysis showed that Japanese porcine MRVs exhibited genetic diversity, although they shared homology with porcine MRV sequences deposited in the DDBJ/EMBL/GenBank database. Several potential intra-genetic reassortment events among MRV strains from pigs, sewage, and humans have been detected in Japan, suggesting zoonotic transmission. Furthermore, homologous recombination events were identified in the M1 and S1 genes of Japanese porcine MRV. These findings imply that different strains of Japanese porcine MRVs share a porcine MRV genomic backbone and have evolved through intra-genetic reassortment and homologous recombination events.
Percutaneous Endoscopic Interlaminar Discectomy for Severe Lumbar Disc Herniation in a 12-year Pediatric Diver: A Case Report, technical note and literature review
Authors: Wu Hui , Zheng Sikuan , He Dingwen , Cheng Xigao
Published: May 2022

Background Lumbar disc herniation(LDH) is rare in pediatric diver. Because of the particularity of age and occupation, which makes the treatment concept of pediatric diver lumbar disc herniation quite different from that of the general population. In this case report, we report a rare case of using percutaneous endoscopic interlaminar discectomy (PEID) successfully treats a 12-year-old professional diver.
Transcriptomic plasticity of the hypothalamic osmoregulatory control centre of the Arabian dromedary camel
Authors: Lin Panjiao , Gillard Benjamin , Pauza Audrys , Alvira-Iraizoz Fernando , Ali Mahmoud , Mecawi Andre , Alim Fatma , Romanova Elena , Burger Pamela , Greenwood Michael , ADEM ABDU , Murphy David
Published: May 2022

Water conservation is vital for life in the desert. The dromedary camel (Camelus dromedarius) produces low volumes of highly concentrated urine, more so when water is scarce, to conserve body water. Two hormones, arginine vasopressin (AVP) and oxytocin (OXT), both produced in the supraoptic nucleus (SON), the core hypothalamic osmoregulatory control centre, are vital for this adaptive process, but the mechanisms that enable the camel SON to cope with osmotic stress are not known. To investigate the central control of water homeostasis in the camel, we first built three dimensional models of the camel SON based on the expression of the AVP and OXT mRNAs in order to facilitate sampling. We then compared the transcriptomes of the SON under control and WD conditions and identified genes that change in expression due to hyperosmotic stress. By comparing camel and rat datasets, we have identified common elements of the WD transcriptomic response network, as well as elements, such as extracellular matrix remodelling and upregulation of angiotensinogen expression, that appear to be unique to the dromedary camel and that may be essential adaptations necessary for life in the desert.