bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving the Prognosis of Pancreatic Cancer Through Early Detection: Protocol for a Prospective Observational Study
Authors: Yamada Reiko , Isaji Shuji , Fujii Takehiro , Mizuno Shugo , Kishiwada Masashi , Murata Yasuhiro , Hayasaki Aoi , Inoue Hiroyuki , Umeda Yuhei , Tanaka Kyosuke , Hamada Yasuhiko , Tsuboi Junya , Kato Toshio , Kondo Yoshihiro , Matsuda Shinsuke , Watanabe Noriko , Ogura Toru , Tamaru Satoshi
Published: July 2021

Background

Pancreatic cancer is associated with high mortality and its rates of detection are very low; as such, the disease is typically diagnosed at an advanced stage. A number of risk factors for pancreatic cancer have been reported and may be used to identify individuals at high risk for the development of this disease.

Objective

The aim of this prospective, observational trial is to evaluate a scoring metric for systematic early detection of pancreatic cancer in Mie Prefecture, Japan.

Methods

Eligible patients aged 20 years and older will be referred from participating clinics in the Tsu City area to the Faculty of Medicine, Gastroenterology, and Hepatology at Mie University Graduate School, until September 30, 2022. Participants will undergo a detailed examination for pancreatic cancer. Data collection will include diagnostic and follow-up imaging data and disease staging information.

Results

The study was initiated in September 2020 and aims to recruit at least 150 patients in a 2-year period. Recruitment of patients is currently still underway. Final data analysis is expected to be complete by March 2025.

Conclusions

This study will provide insights into the feasibility of using a scoring system for the early detection of pancreatic cancer, thus potentially improving the survival outcomes of diagnosed patients.

Trial Registration

UMIN-CTR Clinical Trials Registry UMIN000041624; https://tinyurl.com/94tbbn3s

International Registered Report Identifier (IRRID)

DERR1-10.2196/26898
Implementation of Telemental Health Services Before COVID-19: Rapid Umbrella Review of Systematic Reviews (Preprint)
Authors: Barnett Phoebe , Goulding Lucy , Casetta Cecilia , Jordan Harriet , Sheridan-Rains Luke , Steare Thomas , Williams Julie , Wood Lisa , Gaughran Fiona , Johnson Sonia
Published: July 2021

BACKGROUND

Telemental health care has been rapidly adopted for maintaining services during the COVID-19 pandemic, and a substantial interest is now being devoted in its future role. Service planning and policy making for recovery from the pandemic and beyond should draw on both COVID-19 experiences and the substantial research evidence accumulated before this pandemic.

OBJECTIVE

We aim to conduct an umbrella review of systematic reviews available on the literature and evidence-based guidance on telemental health, including both qualitative and quantitative literature.

METHODS

Three databases were searched between January 2010 and August 2020 for systematic reviews meeting the predefined criteria. The retrieved reviews were independently screened, and those meeting the inclusion criteria were synthesized and assessed for risk of bias. Narrative synthesis was used to report these findings.

RESULTS

In total, 19 systematic reviews met the inclusion criteria. A total of 15 reviews examined clinical effectiveness, 8 reported on the aspects of telemental health implementation, 10 reported on acceptability to service users and clinicians, 2 reported on cost-effectiveness, and 1 reported on guidance. Most reviews were assessed to be of low quality. The findings suggested that video-based communication could be as effective and acceptable as face-to-face formats, at least in the short term. Evidence on the extent of digital exclusion and how it can be overcome and that on some significant contexts, such as children and young people’s services and inpatient settings, was found to be lacking.

CONCLUSIONS

This umbrella review suggests that telemental health has the potential to be an effective and acceptable form of service delivery. However, we found limited evidence on the impact of its large-scale implementation across catchment areas. Combining previous evidence and COVID-19 experiences may allow realistic planning for the future implementation of telemental health.

CLINICALTRIAL
Influence of Mass Media on Italian Web Users During the COVID-19 Pandemic: Infodemiological Analysis (Preprint)
Authors: Rovetta Alessandro , Castaldo Lucia
Published: July 2021

BACKGROUND

Concurrently with the COVID-19 pandemic, the world has been facing a growing infodemic, which has caused severe damage to economic and health systems and has often compromised the effectiveness of infection containment regulations. Although this infodemic has spread mainly through social media, there are numerous occasions on which mass media outlets have shared dangerous information, giving resonance to statements without a scientific basis. For these reasons, infoveillance and infodemiology methods are increasingly exploited to monitor information traffic on the web and make epidemiological predictions.

OBJECTIVE

The purpose of this paper is to estimate the impact of Italian mass media on users’ web searches to understand the role of press and television channels in both the infodemic and the interest of Italian netizens in COVID-19.

METHODS

We collected the headlines published from January 2020 to March 2021 containing specific COVID-19–related keywords published on PubMed, Google, the Italian Ministry of Health website, and the most-read newspapers in Italy. We evaluated the percentages of infodemic terms on these platforms. Through Google Trends, we searched for cross-correlations between newspaper headlines and COVID-19–related web searches. Finally, we analyzed the web interest in infodemic content posted on YouTube.

RESULTS

During the first wave of COVID-19, the Italian press preferred to draw on infodemic terms (rate of adoption: 1.6%-6.3%) and moderately infodemic terms (rate of adoption: 88%-94%), while scientific sources favored the correct names (rate of adoption: 65%-88%). The correlational analysis showed that the press heavily influenced users in adopting terms to identify the novel coronavirus (cross-correlations of ≥0.74 to ≤0.89, P value <.001; maximum lag=1 day). The use of scientific denominations by the press reached acceptable values only during the third wave (approximately 80%, except for the television services Rai and Mediaset). Web queries about COVID-19 symptoms also appeared to be influenced by the press (best average correlation=0.92, P<.007). Furthermore, web users showed pronounced interest in YouTube videos of an infodemic nature. Finally, the press gave resonance to serious “fake news” on COVID-19, which caused pronounced spikes of interest from web users.

CONCLUSIONS

Our results suggest that the Italian mass media have played a decisive role in spreading the COVID-19 infodemic and addressing netizens’ web interest, thus favoring the adoption of terms that are unsuitable for identifying COVID-19. Therefore, the directors of news channels and newspapers should be more cautious, and government dissemination agencies should exert more control over such news stories.
INTRACTABLE HICCUPS (SINGULTUS) IN CASE OF ANXIETY NEUROSIS
Authors: Sheth Nishi
Published: July 2021

Intractable hiccups (singultus) are continuous involuntary spasmodic contraction of diaphragm resulting in inspiration followed by closure of glottis. However, it is naturally occurring common phenomenon but intractable hiccups are a continuous form of hiccups which persist for more than 2 months. This can be tough task for physician to found out the organic cause of hiccups. We report a case of 40-year-old female who had hiccups since more than 2 months and she is known case of anxiety neurosis, for which ongoing treatment with anti-depressants and anti-anxiety is going on. Evaluating a psychogenic origin hiccup is the main consequence here.
IMPACT OF PHYSIOTHERAPY REHABILITATION ON HAND FUNCTION IN POST COLLE’S FRACTURE
Authors: Daf Abhishek
Published: July 2021

Distal radius fractures are the most common types of fractures commonly occurring in pediatric and elderly populations but still have a significant impact on the health and well-being of young adults. Colle’s fracture of the wrist is among the most common bony injuries encountered in emergency practice commonly caused by a fall, landing on an outstretched hand with the wrist in dorsiflexion. The majority of Colle’s fractures are manageable with casting and conservative management. After healing and cast removal, the joint undergoes stiffness that needs prompt physiotherapy management to improve range of motion with muscle and ligament strengthening specifically for the injured hand and wrist affected. The patient’s main concerns were Pain, swelling, and stiffness over the forearm, wrist, and hand. The main clinical findings were pain, reduced ROM, reduced strength, stiffness and inability to perform wrist, and hand movements. Wrist and hand stiffness post Colle’s fracture. Physical therapy rehabilitation has already been proven effective in post-fracture rehabilitation, it includes protocol-based and evidence-based approach involving ROM exercises, stretching and strengthening exercises, mobilization, application of different modalities for symptomatic control, massage therapy, etc. outcomes are gross improvement in ROM, strength on MRC, improvement in the overall function of hand and activities of daily living as per Michigan hand outcome questionnaire, improvement in dexterity as per Jebsen hand dexterity test. Efficacy of physiotherapy rehabilitation has already been established. Early, programmed, evidence, and protocol-based rehabilitation has been found effective in reducing symptoms, improving functional independence, and ability to perform activities of daily living. The study also signifies how avoidance and ignorance can lead to complications that are otherwise preventable.
Structural analysis of high-rise building using ETABS and RSA software
Authors: Pechorskaya Sophia A. , Galishnikova Vera V. , Gebreslassie Shishai B. , Damir Habte Y.
Published: July 2021

There are numerous software applications available to analyze and design massive projects in short time. Most of the software have 2-dimensional and 3-dimen- sional tools, while various structural engineers employ the use of the 3D analysis and design tools in their day-to-day tasks because of its ease to operate and graphical user interface. These tools help in modeling, analyzing, and design of structures much more efficient. Despite the availability of numerous software products, there are confusions on the software to be used in the analysis and design of specific building structures. There is a need of studying the strength and weakness of some of these software tools to help structural engineers in the selection of the best application in their daily tasks. The aim of this study is to investigate the structural analysis of high-rise building with ETABS and RSA software and compare the influences of the structural analysis results from the two software in design. The comparison between the axial forces and moment from the results of ETABS and RSA software are presented. Case studies are considered to analyze the structure with the gravitational loads and lateral loads due to wind load by the two software applications. The case studies include a thirty-stories reinforced concrete building frame. The results of the analysis of the frame are compared and their difference is presented. From the analysis, the results show that, the moments and forces presented from RSA are bigger than that of ETABS.
«… это какой-то новый Гоголь»: Георгий Адамович о Владимире Маяковском
Authors:   Институт мировой лите- ратуры РАН, Терехина Вера
Published: July 2021

В статье рассматривается эволюция взглядов ведущего критика русской эмиграции Г. Адамовича на личность и творчество В. Маяковского. На протяжении полувека в рецензиях, статьях, воспоминаниях Адамович высказывал суждения об отличительных чертах его поэтики, о футуризме и революции, о характере связей с классической литературой, наследием Гоголя, Державина, Некрасова. Делается вывод о значительности и современном звучании ряда критических работ Адамовича.
Пражский след московского «Мусагета»: Семен Рубанович в письме Эллиса (1933)
Authors:   University of Vienna, Поляков Федор
Published: July 2021

В статье рассматриваются взаимоотношения поэта-символиста, переводчика и публициста Эллиса (Льва Кобылинского) и литератора Семена Рубановича, представителя молодого поколения, связанного с московскими символистскими кругами. На основании упоминания имени Рубановича в письме Эллиса к художнику Н. В. Зарецкому (1933) выясняется факт переписки Эллиса с Феодосией (Фанни) Гессе, урожденной Рубанович, сестрой его прежнего соратника и ученика. Эта информация позволяет прокомментировать некоторые упоминания о Семене Рубановиче в воспоминаниях Андрея Белого, а также дополнить наши сведения о пребывании семьи Гессе в Праге.
«Мое участье в зреющей судьбе»
Authors:   Институт русской литературы (Пушкинский Дом) РАН, Царькова Татьяна
Published: July 2021

Статья посвящена до последнего времени малоизвестному в России поэту, но признанному в Европе и США лучшим лириком второй волны русской эмиграции – Д. И. Кленовскому. После кратких биографической справки и обзора критических оценок творчества, в котором акцент поставлен на отзывах Г. Адамовича, названы новые поступления в личный фонд литератора, хранящийся в Рукописном отделе Института русской литературы Российской Академии Наук (Пушкинский Дом).
Paragraph and Its Development Pattern On The Essay Writing Of Elementary School Students
Authors: Budiyono Herman
Published: July 2021

This study aimed to describe the quality of the paragraph and its development pattern in the essay writing of elementary school (Sekolah Dasar – SD) students in Jambi City (Kota Jambi – KJ) (SD-KJ). This study utilized a "quantitative descriptive" design. The population was all essays written by the fifth-grade students of SD-KJ. The sample of this research was 35 paragraphs from the essay writing of the fifth-grade students of SD-KJ. The data analysis steps were searching for frequency distribution of paragraph quality and development pattern; grouping the paragraph frequency distribution according to their quality; counting the percentage of each paragraph quality and type of development pattern; and presenting the results. Regarding to paragraph quality, the results are: (1) paragraph completeness, good (5.71%), poor (68.57%), and bad (25.70%); (2) paragraph unity, good (34.58%); poor (51.42%); and bad (14.28%); (3) paragraph order, good (28.57%); poor (51.42%); and bad (20%); and (4) paragraph coherence, good (54.28%); poor (34.28%); and bad (11.42%). Reffering to the implementation of the paragraph development pattern, the results are paragraph development pattern of comparison and contradiction: 20%, analogy: 5.71%, giving examples: 8.57%, cause and effect: 48.57%; general-specific or specific-general: 11.42%, and classification: 5.71%.
Review of “Developing Writers in Higher Education”
Authors: Ulfiati Lilik
Published: July 2021

Instructors and researchers of writing in higher education often experience discouraged when they find their teaching falling short their expectation even though a number of endeavors they invest in the teaching practices and research works. As a writing teacher for higher education, I feel disappointed when I am not able to present more beneficial support than the motivation to write using appropriate vocabularies, making grammatical sentences consisted of compound or complex ones, organizing ideas of writing or paragraphs, constructing coherence essays and so on. After ineffective attempts at aiding higher education students significantly enhance their writing, I began to review the nature of writing and facets other than the language competences comprising what activities the teachers are necessary to carry out, how the students’ writing practices are applied during their writing process, who are involved in the process of writing and how long the writing activities take place. I have figured out solutions to some questions in the book entitled “Developing Writers in Higher Education”. In this five-section book, Anne Ruggles Gere describes comprehensive longitudinal study about topic concerning on how students in higher education keep practicing their writing process and their writing follow various developmental paths.
A Funky-Formal Fashion Collection: Struggling for a Creative Concept in HUGO BOSS
Authors: Tang Vangkilde Kasper
Published: July 2021

In this case study, we follow a group of five young talented fashion designers in HUGO BOSS charged with creating a new concept for the brand BOSS Orange. The concept is to be neither formal nor funky but, precisely, funky-formal. Based on ethnographic fieldwork among these designers, the case describes in detail how the initial idea of a funky-formal fashion collection gradually grows into a more concrete creative concept for such a collection. In particular, it shows how the designers struggle to get to know the HUGO BOSS brands, to become truly inspired, to generate a compelling concept and,  finally, to make a decision between competing concepts. These processes involve not just the talented designers but also, and not least, the Creative Director of BOSS Orange, making it evident how creativity in fashion is by no means an individual idiosyncrasy but rather a social phenomenon.
The Towards Silence Project: Multiple String Quartets Organize to Perform a New Musical Form in Spatially Variable and Distributed Conditions
Authors: O'Donnell Shannon
Published: July 2021

This case describes an example of a collective making process in the field of performing arts. In 2009, multiple string quartets (many considered world class) organized to perform a new musical composition by Sir John Tavener.  The composition challenged four quartets at a time to perform as an integrated ensemble while sitting apart, in various configurations, and at spatial distances up to 70 feet. The process unfolded in three phases: pre-rehearsals of the first group of quartets in the United Kingdom (UK), a series of rehearsals leading to one premiere performance by the second group of quartets in New York, and a series of rehearsals integrated with additional performances in four distinct venues in the UK. Mid-way through the process, the musicians chose to integrate a simple coordinating technology into their process, to address the difficulties produced by distance. This telling of the case story describes what the musicians did to achieve these unprecedented  performances, given the unusual circumstances, emphasizing how they made decisions and evaluated their work along the way. The case is based on comprehensive fieldwork, including observation, interviews, spatial measurement and diagramming, questionnaires, and analysis of videotape of the rehearsal process.
What is Business Anthropology? An Ethnographic Study of an Explorative Workshop
Authors: Albu Oana Brindusa , Larsen Frederik , Sigurdarson Hallur Tor , Andersen Kirsti Reitan , Lyngfeldt Gorm Hansen Louise
Published: July 2021

The anthropology of organizations is always political; it might take place over shorter, as well as longer, time spans and in singular, pluralistic, or even virtual, settings. This paper addresses such issues by describing and analyzing fieldwork experiences of an academic workshop, which took place at the Copenhagen Business School in 2012 under the title of ‘The Business of Ethnography’. The purpose of the workshop was to create a forum in which to discuss business anthropology as an emerging field or sub-discipline of anthropology. The paper considers three conditions (reflexivity, familiarity, and temporality) which give the mise en abyme configuration of the field – the site where action happens – and pose significant challenges to contemporary business ethnographers. We argue that by acknowledging these three factors one can advance easier towards the ambitious goal of rendering organizational interactions intelligible and meaningful.
Ready for Business: An Anthropology Graduate as Change Management Consultant
Authors: Lee Siew-Peng
Published: July 2021

This paper is a historical, confessional and ethnographic account of a former change management consultant in a global consulting firm who later went on to complete a PhD in social anthropology. Locating herself as both the researcher and informant, the writer gives her ‘native’ account of one model of management consulting that was based on a proprietary ‘method’. She notes how her undergraduate training in anthropology made her a more effective consultant as she tried to make sense of the culture of various client organizations for the specific purpose of designing and developing training materials. By mapping the ways in which anthropological theory and methodology could be aligned to meet the business goals of her clients, the paper aims to persuade both prospective employers and students alike to see how anthropology can be applied effectively in the business world.
Panorama do Zoneamento Ecológico-Econômico no Brasil
Authors: Vagula Paulo  Roberto , Uliana Maira Rodrigues , Arana Alba Regina Azevedo
Published: July 2021

O objetivo do artigo é apresentar o contexto histórico no qual o Zoneamento Ecológico-Econômico (ZEE) foi instituído no Brasil, os marcos legais que o regulamentam e suas diretrizes metodológicas básicas. Trata-se de uma pesquisa básica e documental cujas diretrizes metodológicas básicas partiu da elaboração dos projetos de Zoneamento Ecológico-Econômico estabelecidas pelo Decreto Federal nº 4.297/2002. O trabalho apontou que o Programa de ZEE em quase quarenta anos avançou pouco e nem todas as unidades da federação executaram seus projetos. Os poucos avanços verificados, contudo, confirmam que o ZEE é um excelente instrumento de gestão territorial, atual e relevante, podendo alavancar outros instrumentos para uma gestão territorial mais sustentável.
A influência da rodovia BR 364 no cotidiano e comércio da cidade de Juscimeira – MT: um ensaio de ritmanálise
Authors: Ferreira Emanoel Anésio Andrade , Tarifa José Roberto
Published: July 2021

O presente trabalho busca analisar o fluxo de veículos na rodovia BR 163/364 e sua influência no cotidiano e comércio da cidade de Juscimeira-MT. Por muito tempo a cidade de Juscimeira-MT fazia parte da rota de escoamento do agronegócio, por conta de sua localização, que se caracteriza por estar entre as três maiores cidades de Mato Grosso. Portanto, constata-se que a dinâmica rodoviária influencia no ritmo cotidiano e comercial dessa pequena cidade, algo que foi verificado nessa pesquisa. Foram realizados trabalhos de campo para o levantamento de dados. A partir desta pesquisa foi possível verificar que o uso do território influencia diretamente no ritmo socioeconômico da cidade de Juscimeira-MT e do país.
Mini-invasive treatment of a congenital dacryocystocele by means of microdebrider marsupialization in a newborn
Authors: Furia Domenico di , Pignataro Lorenzo , Gaffuri Michele , Osnaghi Silvia , Battilocchi Ludovica , Cantarella Giovanna
Published: July 2021

Congenital dacryocystocele is a rare clinical condition, more commonly
unilateral, secondary to the defective canalization of the nasolacrimal
duct. In case of failure of conservative treatment, surgical
marsupialization is recommended. We describe the case of a 40-days’old
male newborn treated by means of microdebrider marsupialization.
POPULATION STRUCTURE AND GENE FLOW IN THE SHEEPNOSE MUSSEL (PLETHOBASUS CYPHYUS) AND THEIR IMPLICATIONS FOR CONSERVATION
Authors: Roe Kevin , Schwarz Sara
Published: July 2021

North American freshwater mussel species have experienced substantial
range fragmentation and population reductions. These impacts have the
potential to reduce genetic connectivity among populations and increase
the risk of losing genetic diversity. Thirteen microsatellite loci and
an 883 bp fragment of the mitochondrial ND1 gene were used to assess
genetic diversity, population structure, contemporary and historical
migration rates, and population size changes across the range of the
Sheepnose mussel (Plethobasus cyphyus). Population structure analyses
reveal five populations, three in the Upper Mississippi River Basin and
two in the Ohio River Basin. Sampling locations exhibit a high degree of
genetic diversity and contemporary migration estimates indicate that
migration between populations within river basins is occurring, although
at low rates. but no migration is occurring between the Ohio and
Mississippi river basins. No evidence of bottlenecks was detected, and
almost all locations exhibited the signature of population expansion.
Our results indicate that although anthropogenic activity has altered
the landscape across the range of the Sheepnose, these activities have
yet to be reflected in losses of genetic diversity. Efforts to conserve
sheepnose populations should focus on maintaining existing habitats and
fostering genetic connectivity between extant demes to conserve
remaining genetic diversity for future viable Sheepnose populations.
Long-term responses of benthic invertebrates to rotenone treatment
Authors: Kjærstad Gaute , Arnekleiv Jo , Velle Gaute , Finstad Anders Gravbrøt
Published: July 2021

Biological invasions are regarded as one of the largest threats to
native biodiversity. The eradication of non-native parasites by culling
of hosts are a controversial conservation strategy, particularly when
using indiscriminate methods involving whole ecosystem collateral
damage. While short-term effects are abundantly documented, long-term
surveys are needed to detect potential wider ecosystem effects. Here, we
report a six-year study on effects of the piscicide rotenone on
invertebrate communities from a Norwegian water course using a
Before-After-Control-Impact design. Kick-net samples of benthic
invertebrates were collected from three lentic sampling stations and two
lotic stations two to four times per year in both a control and a
treated watershed. In general, only relatively minor short-term effects
immediately after the treatment on species turnover, measured as
temporal beta-diversity, of benthic invertebrates were observed both in
lentic and lotic locations. However, the lotic fauna was temporarily
severely negatively affected following a period of rotenone exposure
from an upstream lake. Species turnover co-varied markedly between
control and treatment locations, indicating that natural environmental
variation override effects of rotenone treatment. Likewise, the
abundance of invertebrate taxa varied considerably both over time and
between control and treatment locations. Our study indicates minor
short-term (i.e. < one month) or long-term (i.e. four years)
effects of rotenone treatment on benthic invertebrates, but severe
effects on the lotic fauna eight months after treatment. However,
long-term effects are likely to be taxa-specific and vary depending on
habitat connectivity and thus potential for re-colonization and will
differ among locations and among taxa.
‘You’re on mute!’ Does paediatric CF home spirometry require physiologist supervision?
Authors: Fettes Emma , Riley Mollie , Brotherston Stephanie , Doughty Claire , Griffiths Benjamin , Laverty Aidan , Aurora Paul
Published: July 2021

Introduction: The COVID-19 pandemic has accelerated the move towards
home spirometry monitoring, including in children. Our aim was to
determine whether the remote supervision of spirometry by a physiologist
improves the technical quality and failure rate of the manoeuvres.
Method: Children with cystic fibrosis who had been provided with NuvoAir
home spirometers were randomly allocated to either supervised or
unsupervised home spirometry following a detailed training session. Home
spirometry was performed every 2 weeks for 12 weeks. Tests were assigned
a quality factor (QF) using our laboratory grading system as per ATS/ERS
standards, with tests marked from A to D, or Fail. In our laboratory we
aim for QF A in all spirometry tests, but report results of QF B or C
with a cautionary note. QF A was therefore the primary outcome, and QF
A-C the secondary outcome. Results: 61 patients were enrolled; 166
measurements were obtained in the supervised group, and 153 in the
unsupervised group. Significantly more measurements achieved QF A in the
supervised compared to unsupervised group (89% vs 74%; p=
<0.001) whilst proportions reaching grade A-C were similar
(99% vs 95%; p=0.1). All significant declines in spirometry results
had a clinical rather than technical reason. Family/patient feedback for
both arms was very positive. Conclusion: These results suggest that home
spirometry in children should ideally be remotely supervised by a
physiologist, but acceptable results can be obtained if resources do not
allow this, provided that training is delivered and results monitored
according to our protocol.
How to prevent fracture of NiTi files
Authors: Zivkovic Slavoljub , Popovic-Bajic Marijana , Jovanovic-Medojevic Milica , Neskovic Jelena
Published: July 2021

More certain therapeutic and significantly facilitated solution of everyday
endodontic problems are provided by the introduction of NiTi rotary files in
endodontic practice and their proper application. However, their widespread
use has caused more and more frequent fractures and has become a significant
frustrating factor that diminishes their numerous benefits. Torsional stress
and cyclic fatigue are the main reasons for the occurrence of a fracture,
and the frequency of NiTi file fractures is exactly proportional to the
degree of bending of the canal, knowledge of the features of the file, ie.
the skill and expertise of the therapist. The most dominant factor for the
occurrence of fractures is the dentist who, in addition to manual dexterity,
must have a good knowledge of the anatomy of various canal systems and file
design in order to make the best choice for each individual case. Properly
formed access cavity and knowledge of the working part of NiTi files enable
maximum realization of endodontic skills, increased efficiency of
intervention and reduced possibility of error during canal instrumentation.
The special treatment of NiTi alloy and new solutions related to the design
of the working part have significantly increased file flexibility and
resistance to cyclic fatigue. Specific design (reduced number of threads,
change of conicity, interruption of blade continuity), reduced engagement of
file, ie. change of dynamics of movement in the canal (full rotation,
reciprocal, eccentric, transaxial), as well as reduced number of processing
files, have also significantly influenced the reduction of fracture risks.
The aim of this paper was to analyze the most common reasons for the
fracture of NiTi files and emphasize measures and factors that can increase
their safe use and reduce complications during canal instrumentation.
Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons
Authors: Quipildor Gabriela Farias , Mao Kai , Beltran Pedro J. , Barzilai Nir , Huffman Derek M.
Published: July 2021

Similar to insulin,
central administration of insulin-like Growth Factor-1 (IGF-1) can suppress hepatic
glucose production (HGP), but it is unclear if this effect is mediated via
insulin receptors (InsRs) or IGF-1 receptors (IGF-1Rs) in the brain. To this
end, we utilized pharmacologic and genetic approaches in combination with hyperinsulinemic-euglycemic
clamps to decipher the role of these receptors in mediating central effects of IGF-1
and insulin on HGP. In rats, we observed that intracerebroventricular (ICV)
administration of IGF-1 or insulin markedly increased the glucose infusion rate
(GIR) by >50% and suppressed HGP (P<0.001). However, these effects
were completely prevented by preemptive ICV infusion with an IGF-1R and
InsR/IGF-1R Hybrid (HybridRs) blocking antibody.
Likewise, ICV infusion of the InsR antagonist, S961, which also can bind HybridRs,
interfered with the ability of central insulin, but not IGF-1 to increase the
GIR. Furthermore, hyperinsulinemic clamps in mice lacking IGF-1Rs in AgRP
neurons revealed ~30% reduction in the GIR in KO animals, which was explained
by an impaired ability of peripheral insulin to completely suppress HGP (P<0.05).
Signaling studies further revealed an impaired ability of peripheral insulin to
trigger ribosomal S6 phosphorylation or PIP3 production in AgRP neurons lacking
IGF-1Rs. In summary, these data suggest that attenuation of IGF-1Rs signaling in
the MBH, and specifically in AgRP neurons, can phenocopy impaired regulation of
HGP as previously demonstrated in mice lacking InsRs in these cells, suggesting
a previously unappreciated role for IGF-1Rs and/or HybridRs in the regulation
of central insulin/IGF-1 signaling on glucose metabolism.
Inpabasis intermedia, a new species of damselfly from Peru (Odonata: Coenagrionidae); with an illustrated key to all known Inpabasis-species
Authors: Faasen Tim
Published: July 2021

Inpabasis intermedia sp. n. (holotype ♂: Peru, Loreto Región) is described and illustrated. An illustrated key to both sexes is given for all members of the genus. Males of I. intermedia can be distinguished from its congeners by the angled division laterally between dark and light areas of the pterothorax, by the short unbranched paraprocts and rounded cerci which bear only a small apical tooth and by the genital ligula with two long apical processes ending in a flattened hook. Females can be distinguished by the dorsoposteriorly directed posterior prothoracic lobe with straight hind margin. http://www.zoobank.org/urn:lsid:zoobank.org:pub:18F2C9D3-28BC-4329-A001-657860A858AB
Evaluation of Harvested Rainwater Quality As a Drinking Water Source in Urban Land Uses in Western Province Sri Lanka
Authors:   Institute of Engineer, Sri Lanka, Premathilaka A.M.A.M. , Pushpakumara T.D.C. ,   Department of Civil Engineering, University of Moratuwa, Sri Lanka
Published: July 2021

Increasing of population around the world has imposed considerable strains on the water resources. Hence, regulatory authorities have faced significant challenges to expand their water supply schemes not only due to financial constraints but also due to limited water resources. Consequently, there has been a growing interest, especially in developing countries, in harvested roof run off as an alternative source of drinking water. However, in determining the end use and the potential success of such an option, the possible problems associated with water quality need to be analyzed and the feasibility of using rainwater as a source of water for household use should be determined. Therefore, this research study was focus on evaluating roof runoff as a drinking water source in different urban land uses where different urban activities are present. For this purpose, a roof runoff samples were collected from three selected land uses namely industrial, commercial and residential. The samples have collected from each land use with three selected roofing materials which are common to the area. This is to evaluate the roof runoff quality based on the variability of land use pattern as well as the variability on roofing materials. All the collected samples have tested for a range of water quality parameters namely, pH, alkalinity, Hardness, Turbidity, TS, COD, Nitrogen (Ammonia), chloride and biological contaminations. Both uni-variate and stacked area analysis techniques were used in the analysis of test results. Based on the outcomes, recommendations are provided to use harvested roof runoff as a drinking water source in urban land uses in Sri Lanka. Keywords urban land uses; drinking water quality parameters; rainwater harvesting
Ecological Risk Assessment of Benzophenone-4 in Wastewater
Authors:   Innovation Centre of the Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, Lukić Jelena , Đurkić Tatjana , Bakić Tamara , Radulović Jelena , Onjia Antonije
Published: July 2021

Sunscreen products contain ultraviolet (UV) filters. The daily use of benzophenone-type UV filters has led to indirect inputs of benzophenone-4 (BP-4) into the environment. Wastewater treatment plants (WWTP) have proven ineffective in removing benzophenone derivatives, therefore WWTP are classified as major source of BP-4 in surface water. The level of environmental risk due to presence of BP-4 in wastewater was estimated to be moderate to high, whereby dilution factor should be taken into account when considering the ecological risk due to the discharge of wastewater into the recipient.
Flow-Thermal Calculation of E10 Reboiler in the Process of Desorption of Light Hydrocarbons in the Plant “LPG Refinery” Elemir
Authors:   High Vocational School, Zrenjanin, Serbia, Lazić Matilda , Halas Dragan , Salemović Duško , Dedić Aleksandar
Published: July 2021

In this paper, the flow-thermal calculation of reboiler E10 in the process of desorption of light hydrocarbons, which is located in the bottom of the column for stabilization (desorption) of rich absorption oil in the plant "Refinery TNG", Elemir. In reboiler E10, heat is exchanged between warm oil (warmer fluid) and rich absorption oil (colder fluid). The observed reboiler E10 represents a heat exchanger with the so-called two passages. Warmer fluid flows inside the exchanger tube, in two passes; while the absorption oil flows through the annular space in one pass. It is assumed that in the E 10 reboiler, based on the data from the technical-technological documentation, the calculation of the relevant current and thermal quantities required for the process of heating the rich absorption oil can be performed. The results of the control flow-thermal calculation confirmed that the assumed value of the pipe length (and the values that result from and are relevant for the calculation) coincides with the value of the pipe length calculated in the realized calculation for reboiler E10. In this way, the correctness of the used equations for the subject calculation was confirmed. A complete overview of flow and thermal quantities in practice completely describes the operation of the E10 reboiler for heating rich absorption oil.
Natural Adsorbents Based on Metal Oxide Structures for Removal of Lead And Arsene Ions from Aqueous Solution
Authors:   Innovation Centre of the Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, Stanišić Tijana , Karić Nataša , Karanac Milica , Đolić Maja , Ristić Mirjana , Perić-Grujić Aleksandra
Published: July 2021

The aim of this research is to examine the efficiency of raw mineral materials that possess good adsorption and techno-economic properties applicable in real systems for the removal of heavy metal ions, primarily lead and arsenic. The adsorption studies were conducted in batch system. To determine the optimal conditions, the adsorption efficiency of the selected ions was tested by variation of the adsorbents mass (5, 7.5, 10 and 20 mg). The materials used in the experimental work are of mineral origin, whose composition consists mainly of SiO2, Al2O3 and Fe2O3. The characterization of analyzed materials was performed using X-Ray Diffraction (XRD), Fourier-Transform Infrared Spectroscopy (FTIR) and scanning electron microscopy (SEM). The maximum removal efficiency of lead ions is 94.8 %, on the material predominantly composed of loam, while for arsenic it is 47.5 % on material based on sandy loam.
Systematization of functional features of intellectual and innovative determinants of the intensification of the regional economic development
Authors: Khanin Semen , Tulchynska Svitlana , Popelo Olha , Derhaliuk Marta , Ishchejkin Tymur
Published: July 2021

Within the article, economic essence, scientific approaches and modern interpretations of intellectual and innovative development of economic systems are considered. The conditions and measures of the activation of intellectual-innovative determinants of the intensification of the development of regional economic systems are determined. Distribution of resources in the region between individual territories is implemented according to investment strategies of intellectual and innovative development. Considering functional features and factors of influence of intellectual and innovative determinants, the author identifies the guidelines for their implementation in the intensification of development processes in the regions. This allowed to formulate directions for ensuring the effectiveness of intellectual and innovative determinants, which include intensifying cooperation and strengthening export positions, creating competitive advantages of an innovative nature, increasing and adapting competencies and digital skills in the population, balanced territorial development through the cognitive resource allocation.
Připravenost podniků na vzdělávání zaměstnanců s využitím ICT – porovnání zemí Visegrádské čtyřky
Authors: Volfová Monika
Published: July 2021

The rapid growth and use of information and communication technology tools affect both private and business activities. In order to maintain their position, companies invest in their employees, especially in their lifelong training in the field of ICT skills development. This paper examines how companies from the Visegrad Four countries are prepared for employee training using ICT. The aim of the paper is to examine the extent to which companies in these countries provide training to develop or improve ICT skills, what is the level of digital skills in each country and what proportion of companies employ ICT specialists. At the end of the paper, a linear regression is performed to confirm or reject the positive relationship between the three variables – Human Capital, Use of Internet Services and data about enterprises that provide training in order to develop or upgrade the ICT skills of their employees. Data from Community survey on ICT usage in enterprises were collected from Eurostat. Data on the Digital Economy and Society Index (DESI) were collected for comparative analysis. The results suggest that there is no positive relationship between ICT employee training and indicator Human Capital from the DESI index but there is positive relationship between ICT employee training and indicator Use of Internet Services.
paisaje como mediador de nuevas pedagogías y tecnologías
Authors: Goñi Fitipaldo Ana Laura , Piazza Norma , Payssé Marcelo , Inda Hugo
Published: July 2021

La investigación presentada en este artículo se desarrolló en un lapso de doce meses y tuvo como marco procesos de enseñanza-aprendizaje en etapa escolar que consideran al paisaje como espacio estimulador del aprendizaje y vehículo para la aplicación de nuevas herramientas pedagógicas. Participaron educandos y educadores de la escuela rural 88 “Faro José Ignacio” (Uruguay), quienes indagaron y profundizaron en la percepción del paisaje local. El acercamiento al área se propuso a través de herramientas tecnológicas de visualización remota para establecer distintos parámetros, tales como vínculos entre escala y detalle, recorridos cotidianos y apreciación de ecosistemas locales. La incidencia de incorporar estos recursos fue evaluada mediante el análisis de dibujos y relatos realizados por los niños y la comparación de cartografías de paisaje previas y posteriores a su uso. Los resultados se volcaron en formato comunicacional y de contenidos adecuado a la población escolar. El producto final, elaborado de forma participativa, fue la plataforma digital Paisajes Pedagógicos (http://www.plapp.edu.uy), la cual presenta siete puntos de observación con capacidad de visión 360 grados y puntos sensibles que despliegan información adicional (fichas de aves, fichas de vegetales, cambios temporales en la morfología costera). Las visuales pueden ocupar toda la pantalla, ofrecen ayudas para la navegación y posibilidades de orbitar, cambiar de ubicación, agrandar y capturar la imagen, a través de menús auxiliares. Por su diseño metodológico, este proceso-producto es replicable y, como tal, se pretende extender la experiencia a futuro con nuevos proyectos en otras escuelas del país.
cualidades arquitectónicas de las aulas y su relación con la ideación creativa
Authors: Elizondo Andrea Mariel , De la Fuente Luis Alfonso , Mireles Adrián
Published: July 2021

Si bien las personas pueden ser creativas en mayor o menor medida, el potencial creativo está condicionado por el entorno. Por lo tanto, es esencial proveer ambientes adecuados para propiciar el pensamiento creativo. La investigación empírica de la cual se deriva este artículo buscó detectar las características funcionales y ambientales requeridas para facilitar el proceso de ideación en alumnos de Arquitectura. En desarrollo del estudio, estudiantes de la Facultad de Arquitectura de la Universidad Autónoma de Nuevo León (México) evaluaron diferentes aulas en términos de sus cualidades arquitectónicas y el grado de facilidad con que se verifican en su interior tareas relacionadas con el estudio de la disciplina y la generación de ideas creativas. Los resultados obtenidos muestran correlaciones entre la capacidad para propiciar la creatividad y condiciones como la altura, el color, el sonido, la iluminación y la temperatura.
Pasos de libertad. Propuesta transmedia para el fortalecimiento de la apropiación del valor patrimonial
Authors: Fonseca Andrea Carolina , Rodríguez Carlos Mario , Cuervo Diana Camila , Pachón Fernanda Lisseth , Arango Marcela Natalia
Published: July 2021

El presente artículo de reflexión da cuenta de una propuesta para la implementación de Contenidos Educativos Digitales a través de narrativas transmediales que acerquen a las nuevas generaciones a temas como la Ruta Libertadora en Boyacá. El problema de investigación se plantea a partir de la reflexión respecto a la manera de fortalecer y divulgar el valor patrimonial y cultural de dicha Ruta en entornos no convencionales que cumplan una función educativa. Se presentan los desarrollos realizados tras el análisis y diagnóstico de la comunidad escolar en el colegio Silvino Rodríguez de la ciudad de Tunja, a quienes se destina inicialmente un prototipo correspondiente a un lugar de relevancia como es el Puente de Boyacá. Este prototipo incluye elaboración de guion, redacción de contenidos, doblaje de voces, grabación de video, animación, creación de personajes, diagramación, producción de una aplicación móvil y un libro electrónico (e-book). De tal modo, se busca reducir la brecha digital y dinamizar este tipo de contenidos, hacerlos más accesibles y responder a las necesidades detectadas en el trabajo realizado con los estudiantes.
memoria en el proceso de desarrollo y significación de espacios con carácter patrimonial o de ámbito conmemorativo
Authors: Puentes Saily
Published: July 2021

Este artículo de investigación presenta las premisas en torno al tema de memoria, la cual se compone de una visión acerca de su materialización, del vínculo con la construcción colectiva y de la identidad en el espacio público y los edificios, estos dos últimos como componentes de la arquitectura y el urbanismo que constituyen de forma tangible el soporte para el desarrollo y significación de los espacios, como una forma de narración del conflicto de tierra en el contexto colombiano.

En este sentido, se hace uso de un método de investigación mixto a través de elementos cualitativos y cuantitativos, como puntos claves de estudio para determinar el concepto de la memoria por parte de los usuarios y la población, así como de elementos para la evaluación de la misma en la calidad de vida y su relación con la red digital, empleando tres características para sintetizar las acciones y conclusiones de los hallazgos obtenidos.