bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Enrichment as a Method of Data Preprocessing to Enhance Short-Term Wind Power Forecasting
Authors: Zhou Yingya , Ma Linwei , Ni Weidou , Yu Colin
Published: February 2023

Wind power forecasting involves data preprocessing and modeling. In pursuit of better forecasting performance, most previous studies focused on creating various wind power forecasting models, but few studies have been published with an emphasis on new types of data preprocessing methods. Effective data preprocessing techniques and the fusion with the physical nature of the wind have been called upon as potential future research directions in recent reviews in this area. Data enrichment as a method of data preprocessing has been widely applied to forecasting problems in the consumer data universe but has not seen application in the wind power forecasting area. This study proposes data enrichment as a new addition to the existing library of data preprocessing methods to improve wind power forecasting performance. A methodological framework of data enrichment is developed with four executable steps: add error features of weather prediction sources, add features of weather prediction at neighboring nodes, add time series features of weather prediction sources, and add complementary weather prediction sources. The proposed data enrichment method takes full advantage of multiple commercially available weather prediction sources and the physical continuity nature of wind. It can cooperate with any existing forecasting models that have weather prediction data as inputs. The controlled experiments on three actual individual wind farms have verified the effectiveness of the proposed data enrichment method: The normalized root mean square error (NRMSE) of the day-ahead wind power forecast of XGBoost and LSTM with data enrichment is 11% to 27% lower than that of XGBoost and LSTM without data enrichment. In the future, variations on the data enrichment methods can be further explored as a promising direction of enhancing short-term wind power forecasting performance.
Pore Structure Evolution in Sandstone of Underground Gas Storage during Cyclic Injection and Production Based on Nuclear Magnetic Resonance Technology
Authors: Qiu Xiaosong , Liu Hejuan , Liu Mancang , Mao Haijun , Wang Duocai , Ying Qiqi , Ban Shengnan
Published: February 2023

The underground gas storage (UGS) in depleted sandstone reservoirs forms the largest proportion of the UGS market in China. Multiple cycles of natural gas injection and production in the sandstone cause the rapid increase and drawdown of pore pressure, which may induce damage to the rock skeleton structure, and cause complex fluid flow paths in the sandstone reservoir. In this paper, transverse relaxation time (T2), nuclear magnetism resonance imaging, and high-pressure mercury intrusion analysis are combined to evaluate the variation in pore structure of medium-grained sandstone. The results show that cyclic injection and production of fluid leads to a slight increase in total pore volume, indicating that weak damage to rocks occurs. The T2 spectrum at the low pore pressure (10 MPa) and high pore pressure (25 MPa) both show that the shrinkage of the medium-size pores occurs after multiple cycles of injection and production. The pore volume of large-size pores was not highly correlated with the number of cycles. With the increase in pore pressure, the pore volume ratio under high pore pressure increased with the number of cycles, while it fluctuated strongly under low pore pressure.
Recent Development of Fuel Cell Core Components and Key Materials: A Review
Authors: Zhang Yuemeng , Wang Jia , Yao Zhanhui
Published: February 2023

Fuel cells, as key carriers for hydrogen energy development and utilization, provide a vital opportunity to achieve zero-emission energy use and have thus attracted considerable attention from fundamental research to industrial application levels. Considering the current status of fuel cell technology and the industry, this paper presents a systematic elaboration of progress and development trends in fuel cell core components and key materials, such as stacks, bipolar plates, membrane electrodes, proton exchange membranes, catalysts, gas diffusion layers, air compressors, and hydrogen circulation systems. In addition, some proposals for the development of fuel cell vehicles in China are presented, based on the analysis of current supporting policies, standards, and regulations, along with manufacturing costs in China. The fuel cell industry of China is still in the budding stage of development and thus suffers some challenges, such as lagging fundamental systems, imperfect standards and regulations, high product costs, and uncertain technical safety and stability levels. Therefore, to accelerate the development of the hydrogen energy and fuel cell vehicle industry, it is an urgent need to establish a complete supporting policy system, accelerate technical breakthroughs, transformations, and applications of key materials and core components, and reduce the cost of hydrogen use.
The Impact of Sewage Sludge-Sweet Sorghum Blends on the Biogas Production for Energy Purposes
Authors: Prask Hubert , Fugol Małgorzata , Dyjakon Arkadiusz , Głąb Liliana , Sowiński Józef , Whitaker Alena
Published: February 2023

The paper presents research on the impact of adding various forms of sorghum to sewage sludge on the anaerobic digestion process. The use of liquid sewage sludge alone in biogas plants at wastewater treatment plants is inefficient due to the low total solid (dry matter) content of this substrate. The tests revealed that the production of methane in biogas is low and amounted to 17.9% (105.4 Nm3∙Mg−1, VS—volatile solid). Therefore, other substrates should be blended with sewage sludge to increase the total solid of the batch. Sorghum silage, sorghum pomace, and sorghum juice were added to the sewage sludge in various proportions during the research. As a result, the improvement of the biogas process, the stabilization of the biogas production curve, as well as the increase in methane yield were observed. The most biogas and methane were obtained from a mixture of sorghum juice (5%) and sewage sludge (664.8 Nm3∙Mg−1 VS and 53.9%, respectively). Biogas production from other substrates based on sorghum and sewage sludge ranged from 457.4 to 588.8 Nm3∙Mg−1 VS. For a mixture of juice (7%) and sewage sludge, the batch was acidified, and biogas production was only 281.5 Nm3∙Mg−1 VS. Studies have shown that intelligent blending of an alternative raw material (compared to traditional maize silage) with sewage sludge allows for similar biogas yields while maintaining a stable anaerobic digestion process.
Understanding Energy Citizenship: How Cultural Capital Shapes the Energy Transition
Authors: Jansma Sikke R. , Long Le Anh Nguyen , Lee Dasom
Published: February 2023

Community involvement and citizenship have been crucial drivers in energy transitions worldwide. To deepen our understanding of the energy transition and to further promote energy citizenship, we leverage Bourdieu’s concept of cultural capital to shed light on the inequities in community-centered energy transition processes. More specifically, this study demonstrates that cultural capital is an important indicator of an individual’s willingness to participate in renewable energy-related behavior and social movements. Using survey data in the Netherlands as a case study, it finds that depending on the type of energy citizenship, i.e., material participation (investments) or communicative participation (protest), different types of cultural capital are in play. The results of this study imply that a nuanced approach towards both concepts, namely energy citizenship and cultural capital, is needed. The scholarly and practical implications of this study are discussed, and the study concludes with pathways for more comprehensive community engagement.
AI and Energy Justice
Authors: Noorman Merel , Espinosa Apráez Brenda , Lavrijssen Saskia
Published: February 2023

Artificial intelligence (AI) techniques are increasingly used to address problems in electricity systems that result from the growing supply of energy from dynamic renewable sources. Researchers have started experimenting with data-driven AI technologies to, amongst other uses, forecast energy usage, optimize cost-efficiency, monitor system health, and manage network congestion. These technologies are said to, on the one hand, empower consumers, increase transparency in pricing, and help maintain the affordability of electricity in the energy transition, while, on the other hand, they may decrease transparency, infringe on privacy, or lead to discrimination, to name a few concerns. One key concern is how AI will affect energy justice. Energy justice is a concept that has emerged predominantly in social science research to highlight that energy related decisions—in particular, as part of the energy transition—should produce just outcomes. The concept has been around for more than a decade, but research that investigates energy (in)justice in the context of digitalized and data-driven electricity systems is still rather scarce. In particular, there is a lack of scholarship focusing on the challenges and questions that arise from the use of AI technologies in the management of electricity systems. The central question of this paper is, therefore: what may be the implications of the use of AI in smart electricity systems from the perspective of energy justice, and what does this mean for the design and regulation of these technologies?
Performance Evaluation of a Linear CPV/T System in Different Working Conditions
Authors: Renno Carlo , Perone Alessandro , D’Agostino Diana , Minichiello Francesco
Published: February 2023

The performance of Concentrating Photovoltaic and Thermal (CPV/T) systems is also linked to climatic conditions. In this paper, the main purpose is to determine the energy and economic performance of a line-focus CPV/T system used for a residential user, considering three cities with different weather conditions: Amsterdam (The Netherlands), Marrakech (Morocco), and Salerno (Italy). A modular configuration of a CPV/T system, with a concentration factor equal to 90 and module of 60 Triple-Junction (TJ) cells, is considered. The electrical power is linked to the values of TJ cell temperature and concentrated radiation by an experimental model. Electric production is highly influenced by the TJ cell temperature values. Hence, Marrakech presents lower power generation in summer than Amsterdam, 126 W, and 134 W respectively; in winter season the trend is reversed. However, the electric production in Marrakech will be higher because presents a higher number of daylight hours than other cities considered. The CPV/T system electrical and thermal producibility is evaluated for each city and for typical winter and summer sunny days, together with the modules number able to obtain the investment profitability.
Optimization-Based Operation of District Heating Networks: A Case Study for Two Real Sites
Authors: Schindler Markus , Gnam Lukas , Puchegger Markus , Medwenitsch Karina , Jasek Patricia
Published: February 2023

To achieve the ambitious targets of net-zero greenhouse gas emissions by 2050, there is a need for change in all parts of society, industry, and mobility, as well as in all energy sectors. For this purpose, sector coupling plays a crucial role, e.g., in the form of coupling the electricity with the heat sector using power-to-heat systems. In this article, the effects of the integration of intermittent wind energy via a direct cable, as well as the integration of a boiler into district heating systems powered by a biomass plant and/or a gas boiler, are investigated. Sector coupling in the district heating networks is achieved via the integration of a boiler connected to a local grid station and the use of two air-to-water and two water-to-water heat pumps, which are solely powered by electricity produced by local wind turbines. Furthermore, this work evaluates the economic impacts of the exploding energy prices on the sustainability of district heating systems. Our analysis shows that despite high electricity prices, a reduction in fossil-fuel-based energy generators in the winter season can be determined, and thus a sustainable heat supply can be ensured.
Data-Driven Model for Real-Time Estimation of NOx in a Heavy-Duty Diesel Engine
Authors: Falai Alessandro , Misul Daniela Anna
Published: February 2023

The automotive sector is greatly contributing to pollutant emissions and recent regulations introduced the need for a major control of, and reduction of, internal combustion engine emissions. Artificial intelligence (AI) algorithms have proven to hold the potential to be the thrust in the state-of-the-art for engine-out emission prediction, thus enabling tailored calibration modes and control solutions. More specifically, the scientific literature has recently witnessed strong efforts in AI applications for the development of nitrogen oxides (NOx) virtual sensors. These latter replace physical sensors and exploit AI algorithms to estimate NOx concentrations in real-time. Still, the calibration of the algorithms, together with the appropriate choice of the specific metric, strongly affects the prediction capability. In the present paper, a machine learning-based virtual sensor for NOx monitoring in diesel engines was developed, based on the Extreme Gradient Boosting (XGBoost) machine learning algorithm. The latter is commonly used in the literature to deploy virtual sensors due to its high performance, flexibility and robustness. An experimental campaign was carried out to collect data from the engine test bench, as well as from the engine electronic control unit (ECU), for the development and calibration of the virtual sensor at steady-state conditions. The virtual sensor has, since then, been tested throughout on an on-road driving mission to assess its prediction performance in dynamic conditions. In stationary conditions, its prediction accuracy was around 98%, whereas it was 85% in transient conditions. The present study shows that AI-based virtual sensors have the potential to significantly improve the accuracy and reliability of NOx monitoring in diesel engines, and can, therefore, play a key role in reducing NOx emissions and improving air quality.
Multi-Century Reconstruction of Pandora Moth Outbreaks at the Warmest/Driest Edge of a Wide-Ranging Pinus Species
Authors: O’Neill Leo , Fulé Peter Z. , Hofstetter Richard W.
Published: February 2023

Pandora moths (Coloradia pandora subsp. davisi Barnes and Benjamin) have been observed to reach epidemic populations on the Kaibab Plateau, resulting in relatively small, localized defoliation events of ponderosa (Pinus ponderosa Lawson). We reconstructed the historical pandora moth outbreak regime using tree rings and forest health records to explore how exogenous factors, climate, and fire, are related to outbreak dynamics close to the driest range of ponderosa pine. We collected eight tree-ring chronologies dating back 400 years, geographically dispersed around the plateau, and inferred past outbreaks by comparison with non-host tree-ring chronologies, weather records, and historical observations. Eleven outbreaks were detected between 1744 and the present, many of them occurring at all the sites. Outbreaks were found to be synchronous, typically lasting 10 years at 25-year intervals. Interruption of the frequent fire regime that prevailed prior to 1880 was associated with a shift to shorter, less frequent outbreaks. Dry to wet oscillations in climate were correlated with outbreak initiations. Pandora moth outbreaks appear to have been an intrinsic part of the Kaibab Plateau’s forest ecosystems, though more research is needed to understand outbreak effects on the ecosystem and future directions of the moth–host relationship under climate warming.
Spatio-Temporal Pattern, Evolution and Influencing Factors of Forest Carbon Sinks in Zhejiang Province, China
Authors: Wu Weiguang , Zhu Ying , Wang Yifei
Published: February 2023

Zhejiang Province, charged with the task of opening “an important window”, should take the lead in the implementation of the national “carbon peak, carbon neutral” strategy. The intention of this study is to start from the intersection of economics and geography, and on the basis of GIS analysis, use the spatial Dubin model to study the spatio-temporal evolution trend, key influencing factors, and spatial spillover effects of forest carbon sequestration in 72 districts and counties of Zhejiang Province from 2000 to 2020, to provide a theoretical and practical reference for how to formulate regional synergistic forest sink enhancement measures and help Zhejiang achieve the goal of carbon neutrality. The conclusions are as follows: (1) From 2000 to 2020, the overall growth of forest carbon sequestration in all regions and counties of Zhejiang Province was relatively high, but the regional differences were large. The concentration center and range moved to the southwest. (2) If the spatial effect is considered, the increase of per capita GDP, road density, and deforestation will reduce the forest carbon sequestration, and the conservation of ecological public welfare forests will have a significant positive relationship with the forest carbon sequestration.
The Interactive Effects of Nitrogen Addition and Ozone Pollution on Cathay Poplar-Associated Phyllosphere Bacterial Communities
Authors: Li Pin , Ran Kun , Gao Feng
Published: February 2023

Ground-level ozone (O3) can adversely impact tree productivity and the service functions of forest ecosystems. The deposition of atmospheric nitrogen (N) can enhance nutrient availability and mitigate the O3-mediated impairment of plant–soil–microbe systems. Interactions between plants and associated microbial communities are integral to the ability of these plants to resist environmental stressors, yet studies examining the impact of increased O3 and N levels, alone or in combination, on these phyllosphere bacterial communities have been lacking to date. Accordingly, this study was conducted to examine the impact of O3 (charcoal-filtered air vs. non-filtered ambient air + 40 ppb of O3), N addition (0, 50, and 100 kg N ha−1 year−1), and a combination of these treatments on the phyllosphere bacterial communities associated with Cathay poplars. Higher O3 levels were found to significantly reduce the relative abundance of Gammaproteobacteria phyla while increasing the relative abundance of the dominant Alphaproteobacteria and Betaproteobacteria, with these effects being independent of N levels. Consistently, while marked differences in the composition of phyllosphere bacterial communities were observed as a function of O3 treatment conditions, they were largely similar across N treatments. Higher O3 levels contributed to significant reductions in α diversity, including both observed OTUs and phylogenetic diversity, when no N or low levels of N were added. α diversity was not affected by the N addition irrespective of O3 levels. A significant correlation was observed between photosynthesis rates and both α diversity and phyllosphere bacterial community composition, indicating a close relationship between photosynthetic activity and this microbial community. Together, these data offer new ecological insights regarding O3-induced changes in the makeup of bacterial communities present on plant surfaces, providing a foundation for efforts to formulate novel management strategies aimed at adapting environmental stressors under conditions of O3 pollution and in N-enriched environments.
Optimal Enzymatic Hydrolysis of Sweet Lupine Protein towards Food Ingredients
Authors: Pasarin Diana , Lavric Vasile , Enascuta Cristina Emanuela , Ghizdareanu Andra-Ionela , Matei Catalin Bogdan
Published: February 2023

Although its high protein content, bioactive compounds, and dietary fibers have many health benefits, lupine (Lupinus sp.) was undervalued as a resourceful plant. In the last years, however, the number of studies on the use of lupine as a potential food ingredient has increased. In this study, obtaining a sweet lupine protein concentrate (SLPC) hydrolysate with a high degree of hydrolysis (DH) and a simultaneous low intensity of bitterness was pursued. The experimental design was carried out, according to Taguchi methodology, using three experimental parameters: enzyme concentration (0.5–1.5%), temperature (50–60 °C), and time (1–4 h), with three levels each. The optimal conditions for the enzymatic hydrolysis process of SLPC with Alcalase 2.4 L were enzyme concentration 1.5%, temperature 50 °C, and time 4 h, for which the best DH, 41.96%, was achieved. The SLPC hydrolysate as a food ingredient was characterized in terms of DH, bitter taste intensity, amino acid profile, and techno-functional properties. The results showed an increase of water binding capacity to 1.45 g/g, emulsification activity of 50.91%, and 92% stability of the emulsion, while the evaluated intensity of bitterness was 4.6 on a 7- point scale. Based on its technological, functional, sensory, and chemical characteristics, this study recommends the use of SLPC hydrolysate as a food ingredient in various food matrices.
Impact of Cavitation Jet on the Structural, Emulsifying Features and Interfacial Features of Soluble Soybean Protein Oxidized Aggregates
Authors: Guo Yanan , Liu Caihua , Wang Yichang , Ren Shuanghe , Zheng Xueting , Zhang Jiayu , Cheng Tianfu , Guo Zengwang , Wang Zhongjiang
Published: February 2023

A cavitation jet can enhance food proteins’ functionalities by regulating solvable oxidized soybean protein accumulates (SOSPI). We investigated the impacts of cavitation jet treatment on the emulsifying, structural and interfacial features of soluble soybean protein oxidation accumulate. Findings have shown that radicals in an oxidative environment not only induce proteins to form insoluble oxidative aggregates with a large particle size and high molecular weight, but also attack the protein side chains to form soluble small molecular weight protein aggregates. Emulsion prepared by SOSPI shows worse interface properties than OSPI. A cavitation jet at a short treating time (<6 min) has been shown to break the core aggregation skeleton of soybean protein insoluble aggregates, and insoluble aggregates into soluble aggregates resulting in an increase of emulsion activity (EAI) and constancy (ESI), and a decrease of interfacial tension from 25.15 to 20.19 mN/m. However, a cavitation jet at a long treating time (>6 min) would cause soluble oxidized aggregates to reaggregate through an anti-parallel intermolecular β-sheet, which resulted in lower EAI and ESI, and a higher interfacial tension (22.44 mN/m). The results showed that suitable cavitation jet treatment could adjust the structural and functional features of SOSPI by targeted regulated transformation between the soluble and insoluble components.
Organic Acid Accumulation and Associated Dynamic Changes in Enzyme Activity and Gene Expression during Fruit Development and Ripening of Common Loquat and Its Interspecific Hybrid
Authors: Deng Honghong , Li Xuelian , Wang Yang , Ma Qiaoli , Zeng Yuge , Xiang Yinchun , Chen Mingmin , Zhang Huifen , Xia Hui , Liang Dong , Lv Xiulan , Wang Jin , Deng Qunxian
Published: February 2023

Loquats have gained increasing attention from consumers and growers for their essential nutrients and unusual phenology, which could help plug a gap period at market in early spring. Fruit acid is a critical contributor to fruit quality. The dynamic changes in organic acid (OA) during fruit development and ripening of common loquat (Dawuxing, DWX) and its interspecific hybrid (Chunhua, CH) were compared, as well as the corresponding enzyme activity and gene expression. At harvest, titratable acid was significantly lower (p ≤ 0.01) in CH (0.11%) than in DWX loquats (0.35%). As the predominant OA compound, malic acid accounted for 77.55% and 48.59% of the total acid of DWX and CH loquats at harvest, followed by succinic acid and tartaric acid, respectively. PEPC and NAD-MDH are key enzymes that participate in malic acid metabolism in loquat. The OA differences in DWX loquat and its interspecific hybrid could be attributed to the coordinated regulation of multiple genes and enzymes associated with OA biosynthesis, degradation, and transport. The data obtained in this work will serve as a fundamental and important basis for future loquat breeding programs and even for improvements in loquat cultural practices.
Salicylic Acid and Jasmonic Acid Increase the Polysaccharide Production of Nostoc flagelliforme via the Regulation of the Intracellular NO Level
Authors: Han Cheng-Feng , Liu Shu-Ting , Yan Rong-Rong , Li Jian , Chen Ni , Zhang Le-Le , Jia Shi-Ru , Han Pei-Pei
Published: February 2023

To significantly improve the polysaccharide production of Nostoc flagelliforme, a total of 12 chemicals were evaluated for their effects on polysaccharide accumulation. The results showed that salicylic acid and jasmonic acid increased the accumulation of the polysaccharides in N. flagelliforme significantly, by more than 20%. Three polysaccharides, namely control-capsule polysaccharide, salicylic acid-capsule polysaccharide, and jasmonic acid-capsule polysaccharide, were extracted and purified from N. flagelliforme under normal, salicylic acid, and jasmonic acid culture conditions, respectively. Their chemical compositions slightly differed regarding the total sugar and uronic acid contents, with average molecular weights of 2.06 × 103, 2.16 × 103 and 2.04 × 103 kDa, respectively. They presented similar Fourier transform infrared spectra and no significant difference in antioxidant activity. It was revealed that the salicylic acid and jasmonic acid significantly increased the level of nitric oxide. By investigating the effects of the exogenous nitric oxide scavenger and nitric oxide donor on the nitric oxide levels and polysaccharide yield of N. flagelliforme, the results showed that the increase in intracellular nitric oxide levels might be an important factor promoting the accumulation of polysaccharides. These findings provide a theoretical foundation for enhancing the yield of secondary metabolites by regulating the intracellular nitric oxide levels.
Bioactive Compounds as Inhibitors of Inflammation, Oxidative Stress and Metabolic Dysfunctions via Regulation of Cellular Redox Balance and Histone Acetylation State
Authors: Kang Hyunju , Kim Bohkyung
Published: February 2023

Bioactive compounds (BCs) are known to exhibit antioxidant, anti-inflammatory, and anti-cancer properties by regulating the cellular redox balance and histone acetylation state. BCs can control chronic oxidative states caused by dietary stress, i.e., alcohol, high-fat, or high-glycemic diet, and adjust the redox balance to recover physiological conditions. Unique functions of BCs to scavenge reactive oxygen species (ROS) can resolve the redox imbalance due to the excessive generation of ROS. The ability of BCs to regulate the histone acetylation state contributes to the activation of transcription factors involved in immunity and metabolism against dietary stress. The protective properties of BCs are mainly ascribed to the roles of sirtuin 1 (SIRT1) and nuclear factor erythroid 2–related factor 2 (NRF2). As a histone deacetylase (HDAC), SIRT1 modulates the cellular redox balance and histone acetylation state by mediating ROS generation, regulating nicotinamide adenine dinucleotide (NAD+)/NADH ratio, and activating NRF2 in metabolic progression. In this study, the unique functions of BCs against diet-induced inflammation, oxidative stress, and metabolic dysfunction have been considered by focusing on the cellular redox balance and histone acetylation state. This work may provide evidence for the development of effective therapeutic agents from BCs.
Antimelanogenic Effects of Curcumin and Its Dimethoxy Derivatives: Mechanistic Investigation Using B16F10 Melanoma Cells and Zebrafish (Danio rerio) Embryos
Authors: Jeon Hwang-Ju , Kim Kyeongnam , Kim Chaeeun , Lee Sung-Eun
Published: February 2023

Regulation of melanin production via the MC1R signaling pathway is a protective mechanism of the skin of living organisms against exposure to ultraviolet rays. The discovery of human skin-whitening agents has been one of the most intense pursuits of the cosmetic industry. The MC1R signaling pathway is activated by its agonist, alpha-melanocyte stimulating hormone (α-MSH), and mainly regulates melanogenesis. Here, we evaluated the antimelanogenic activities of curcumin (CUR) and its two derivatives, dimethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC), in B16F10 mouse melanoma cells and zebrafish embryos. CUR and BDMC reduced the α-MSH-induced melanin production in B16F10 cells and also downregulated the expression of the melanin-production-related genes Tyr, Mitf, Trp-1, and Trp-2. Moreover, the biological activity of these two compounds against melanogenesis was confirmed in in vivo experiments using zebrafish embryos. However, the highest concentration of CUR (5 µM) resulted in slight malformations in zebrafish embryos, as indicated by acute toxicity tests. In contrast, DMC did not show any biological activity in vitro or in vivo. Conclusively, BDMC is a strong candidate as a skin-whitening agent.
Antioxidant and In Vivo Hypoglycemic Activities of Ethanol Extract from the Leaves of Engelhardia roxburghiana Wall, a Comparative Study of the Extract and Astilbin
Authors: Guo Xiaoqiang , Zhou Ting , Xing Hongxia , Zhang Yucheng , Fang Jingmei , Kang Tairan , Yao Caimei , Yan Jun , Huang Yaxuan , Yao Qian
Published: February 2023

The leaves of Engelhardia roxburghiana Wall (LERW) has been used as sweet tea in China throughout history. In this study, the ethanol extract of LERW (E-LERW) was prepared and the compositions were identified by HPLC-MS/MS. It indicates that astilbin was the predominant component in E-LERW. In addition, E-LERW was abundant in polyphenols. Compared to astilbin, E-LERW presented much more powerful antioxidant activity. The E-LERW also had stronger affinity with α-glucosidase and exerted more vigorous inhibitory effect on the enzyme. Alloxan-induced diabetic mice had significantly elevated glucose and lipid levels. Treatment with E-LERW at the medium dose (M) of 300 mg/kg could reduce the levels of glucose, TG, TC, and LDL by 16.64%, 12.87%, 32.70%, and 22.99%, respectively. In addition, E-LERW (M) decreased food intake, water intake, and excretion by 27.29%, 36.15%, and 30.93%, respectively. Moreover, E-LERW (M) therapy increased the mouse weight and insulin secretion by 25.30% and 494.52%. With respect to the astilbin control, E-LERW was more efficient in reducing the food and drink consumption and protecting pancreatic islet and body organs from alloxan-induced damage. The study demonstrates that E-LERW may be a promising functional ingredient for the adjuvant therapy of diabetes.
Bos indicus Carcasses Suspended by the Pelvic Bone Require a Shorter Aging Time to Meet Consumer Expectations Regarding Meat Quality
Authors: Baldassini Welder , Coutinho Marcelo , Rovadoscki Gregori , Menezes Bruna , Tagiariolli Murilo , Torrecilhas Juliana , Leonel Júlia , Pereira Guilherme , Curi Rogério , Machado Neto Otávio , Chardulo Luis Artur
Published: February 2023

This study evaluated the effects of hanging the carcass by the Achilles tendon (AS) versus pelvic suspension (PS) on meat quality traits. Bos indicus carcasses of two distinct biological types/sex categories comprised 10 young Brangus heifers and 10 Nellore bulls which were finished in a feedlot. Half-carcasses of each biological type/sex category were randomly hung using Achilles suspension (n = 20, AS) or pelvic suspension (n = 20, PS) for 48 h. At boning, longissimus samples were collected for evaluation by untrained consumers for tenderness, liking of flavor, juiciness and overall acceptability, after aging for 5 or 15 days. Objective samples were also tested for shear force (SF), Minolta meat colour, ultimate pH, cooking loss (CL) and purge loss (PL). There was a positive effect (p < 0.01) of PS on the sensory tenderness of Nellore bulls and Brangus heifers aged for 5 days compared to the AS method. At 15 days of aging, difference in sensory tenderness was observed (p < 0.05) in either group. Additionally, an interaction occurred between the suspension method and the aging of Nellore beef (p < 0.05) on liking of flavor, juiciness and overall acceptance, while the same effects were not observed for Brangus beef (p > 0.05). Nellore carcasses submitted to PS tended (p = 0.06) to produce more tender meat than those submitted to AS (SF = 44.62 ± 6.96 vs. 50.41 ± 8.04 N), and lower CL (p < 0.05) were found (27.7 vs. 30.9%). Carcass-suspension methods did not influence meat color, pH or PL in either group (p > 0.05). The PS contributes to improve the quality of Bos indicus bulls loins; in addition, this method allows a reduction in the aging time from 15 to 5 days, and it can be used to supply meat consumer markets which accept a certain level of eating quality.
Visual Function in Children with GNAO1-Related Encephalopathy
Authors: Gambardella Maria Luigia , Pede Elisa , Orazi Lorenzo , Leone Simona , Quintiliani Michela , Amorelli Giulia Maria , Petrianni Maria , Galanti Marta , Amore Filippo , Musto Elisa , Perulli Marco , Contaldo Ilaria , Veredice Chiara , Mercuri Eugenio Maria , Battaglia Domenica Immacolata , Ricci Daniela
Published: February 2023

Background: GNAO1-related encephalopathies include a broad spectrum of developmental disorders caused by de novo heterozygous mutations in the GNAO1 gene, encoding the G (o) subunit α of G-proteins. These conditions are characterized by epilepsy, movement disorders and developmental impairment, in combination or as isolated features. Objective: This study aimed at describing the profile of neurovisual competences in children with GNAO1 deficiency to better characterize the phenotype of the disease spectrum. Methods: Four male and three female patients with confirmed genetic diagnosis underwent neurological examination, visual function assessment, and neurovisual and ophthalmological evaluation. Present clinical history of epilepsy and movement disorders, and neuroimaging findings were also evaluated. Results: The assessment revealed two trends in visual development. Some aspects of visual function, such as discrimination and perception of distance, depth and volume, appeared to be impaired at all ages, with no sign of improvement. Other aspects, reliant on temporal lobe competences (ventral stream) and more related to object–face exploration, recognition and environmental control, appeared to be preserved and improved with age. Significance: Visual function is often impaired, with patterns of visual impairment affecting the ventral stream less.
Re-Evaluation of Genotyping Methodologies in Cattle: The Proficiency of Imputation
Authors: Gershoni Moran , Shirak Andrey , Ben-Meir Yehoshav , Shabtay Ariel , Cohen-Zinder Miri , Seroussi Eyal
Published: February 2023

In dairy cattle, identifying polymorphisms that contribute to complex economical traits such as residual feed intake (RFI) is challenging and demands accurate genotyping. In this study, we compared imputed genotypes (n = 192 cows) to those obtained using the TaqMan and high-resolution melting (HRM) methods (n = 114 cows), for mutations in the FABP4 gene that had been suggested to have a large effect on RFI. Combining the whole genome sequence (n = 19 bulls) and the cows’ BovineHD BeadChip allowed imputing genotypes for these mutations that were verified by Sanger sequencing, whereas, an error rate of 11.6% and 10.7% were encountered for HRM and TaqMan, respectively. We show that this error rate seriously affected the linkage-disequilibrium analysis that supported this gene candidacy over other BTA14 gene candidates. Thus, imputation produced superior genotypes and should also be regarded as a method of choice to validate the reliability of the genotypes obtained by other methodologies that are prone to genotyping errors due to technical conditions. These results support the view that RFI is a complex trait and that searching for the causative sequence variation underlying cattle RFI should await the development of statistical methods suitable to handle additive and epistatic interactions.
Sexual Behaviour and Attitudes towards Safe Sex of Youth Receiving Antiretroviral Care at Public Health Facilities in Palapye District, Botswana
Authors: Diura-Vere Onai , Mokgatle Mathildah M. , Oguntibeju Oluwafemi O.
Published: February 2023

Background: Sexual behaviour of HIV-infected youths is very important in determining the direction of the HIV epidemic, as these youths are reservoirs of HIV and can propagate its transmission if they engage in risky sexual behaviours. However, support structures for secondary prevention are weak even in healthcare settings. There is a need to understand the sexual behaviour of these youths and, in turn, tailor appropriate secondary prevention strategies, hence the current study was designed to assess sexual behaviour and attitudes towards safe sex of youth receiving antiretroviral care at public health facilities in Palapye district, Botswana. Method: This quantitative, descriptive cross-sectional survey was used to describe the sexual behaviour and attitudes towards safe sex and identify factors associated with risky sexual behaviours among HIV-infected youths aged between 15 and 19 years receiving antiretroviral therapy (ART) care from public healthcare facilities in Palapye District, Botswana. Results: A total of 188 youths participated in this study, 56% being females while 44% were males. We reported that 15.4% had ever had sex. At their last sexual encounter, more than half of the youths (51.7%) had not used condoms. More than a third of the participants were under the influence of alcohol during their last sexual experience. Generally, the youths had good attitudes towards safe sex, as most youths said they would prioritise protecting their sexual partners and themselves from HIV and STIs. Alcohol use, substance use and not considering religion as important were strongly associated with having ever had sex. Conclusions: A significant proportion of HIV-infected youths are sexually active, whereas their preventive practices such as condom use are poor despite good attitudes towards safe sex. Alcohol use, substance use and not perceiving religion as important were associated with risky sexual behaviours.
The Role of Family Resilience and Pandemic Burnout on Mental Health: A Two-Wave Study in China
Authors: Tang Catherine So-kum , Siu Tiffany Sok U , Chow Tak Sang , Kwok Helen Sin-Hang
Published: February 2023

Family resilience refers to the processes through which a family adapts to and bounces back from adversities. Pandemic burnout refers to feeling emotionally exhausted, cynical, and lack of accomplishment during the pandemic and/or toward various preventive polices and measures. This two-wave, region-wide, longitudinal study included 796 adult participants residing in mainland China. Participants completed online surveys at two time points during the COVID-19 pandemic. Time 1 (T1) survey was conducted when the number of new infected cases in China stabilized, while Time 2 (T2) was conducted 5 months later when there was a sudden surge of new infected cases. Results of a hierarchical regression analysis revealed that the interaction and main effects of pandemic burnout and family resilience at T2 showed significant incremental prediction of depression and anxiety at T2, after controlling for demographic as well as individual and family resilience at T1. These results supported the hypotheses that current family resilience functions as a protective factor, whereas pandemic burnout functions as a risk factor of mental health during successive waves of pandemic outbreaks. In particular, family resilience at T2 mitigated the negative impact of high pandemic burnout on anxiety and depression at T2.
The Role of the COVID-19 Crisis in Shaping Urban Planning for Improved Public Health: A Triangulated Study
Authors: Ferhati Koudoua , Chouguiat Belmallem Saliha , Burlea-Schiopoiu Adriana
Published: February 2023

This paper aims to assess the impact of the COVID-19 pandemic on the link between urban planning practices and public health. A triangulated study was conducted to gain a comprehensive understanding of the topic. The first phase consisted of semi-structured interviews with health and urban planning experts, which were analyzed with the aid of Artificial Intelligence tools. The second phase involved an on-site investigation in the city of Algiers, including a survey, site visits, and a thorough analysis of the master plan for land use and urban planning. The findings emphasize the critical importance of a comprehensive health-centric approach to city design, improved governance and management practices, community involvement, and political commitment to prioritize health in urban planning. Furthermore, the results proved a strong correlation between prioritizing public health in urban planning practices and residents’ satisfaction with the city’s response to the COVID-19 pandemic. In conclusion, it is necessary to consider public health as a priority in urban planning practices and as a need for all stakeholders to work towards a healthier and more equitable urban environment.
Assessing the Land Reclamation Suitability of Beam Fabrication and Storage Yard in Railway Construction: An AHP-MEA Method
Authors: Cheng Baoquan , Li Jianchang , Tao Jingfang , Huang Jianling , Chen Huihua
Published: February 2023

Railway construction contributes to socio-economic development but causes the occupation and destruction of land resources. How to effectively restore the temporary land and achieve efficient and rational reuse therefore becomes particularly important. The beam fabrication and storage yard (BFSY), as a large temporary facility during railway construction, occupies a large area of land. However, BFSYs damage the land in the way of pressing and may harden the ground to a high degree due to the use of high-density pile foundations, adversely affecting the soil properties. Therefore, this research aims to develop a model for evaluating the land reclamation suitability (LRS) of BFSY. The LRS evaluation indicator system of BFSY was firstly constructed based on the literature review and expert interviews. Then, an indicator-based model for assessing the LRS of BFSY was developed by integrating the analytic hierarchy process (AHP) model and the matter-element analysis (MEA) model. A case project in China was chosen to demonstrate and validate the developed model, and results show that the proposed model can rationally evaluate the LRS of BFSY in railway construction. The findings of this research enrich the knowledge system of sustainable railway construction and guide construction managers to conduct practical suitability assessments of land reclamation.
Research and Public Interest in Mindfulness in the COVID-19 and Post-COVID-19 Era: A Bibliometric and Google Trends Analysis
Authors: Kwon Chan-Young
Published: February 2023

Public and research interest in mindfulness has been growing, and the Coronavirus disease 2019 (COVID-19) pandemic seems to have accelerated this growth. This study was conducted to investigate the public and research interest in mindfulness in the context of COVID-19. The term ‘Mindfulness’ was searched in Google Trends, and data were collected from December 2004 to November 2022. The relationship between the relative search volume (RSV) of ‘Mindfulness’ and that of related topics was analyzed, and ‘Top related topics and queries’ for the search term ‘Mindfulness’ were investigated. For bibliometric analysis, a search was conducted in the Web of Science database. Keyword co-occurrence analysis was conducted, and a two-dimensional keyword map was constructed using VOSviewer software. Overall, the RSV of ‘Mindfulness’ increased slightly. The RSVs of ‘Mindfulness’ and ‘Antidepressants’ showed an overall significant positive correlation (r = 0.485) but a statistically significant negative correlation during the COVID-19 era (−0.470). Articles on mindfulness in the context of COVID-19 were closely related to depression, anxiety, stress, and mental health. Four clusters of articles were identified, including ‘mindfulness’, ‘COVID-19’, ‘anxiety and depression’, and ‘mental health’. These findings may provide insights into potential areas of interest and identify ongoing trends in this field.
Urban Surface Ozone Concentration in Mainland China during 2015–2020: Spatial Clustering and Temporal Dynamics
Authors: Yao Youru , Ma Kang , He Cheng , Zhang Yong , Lin Yuesheng , Fang Fengman , Li Shiyin , He Huan
Published: February 2023

Urban ozone (O3) pollution in the atmosphere has become increasingly prominent on a national scale in mainland China, although the atmospheric particulate matter pollution has been significantly reduced in recent years. The clustering and dynamic variation characteristics of the O3 concentrations in cities across the country, however, have not been accurately explored at relevant spatiotemporal scales. In this study, a standard deviational ellipse analysis and multiscale geographically weighted regression models were applied to explore the migration process and influencing factors of O3 pollution based on measured data from urban monitoring sites in mainland China. The results suggested that the urban O3 concentration in mainland China reached its peak in 2018, and the annual O3 concentration reached 157 ± 27 μg/m3 from 2015 to 2020. On the scale of the whole Chinese mainland, the distribution of O3 exhibited spatial dependence and aggregation. On the regional scale, the areas of high O3 concentrations were mainly concentrated in Beijing-Tianjin-Hebei, Shandong, Jiangsu, Henan, and other regions. In addition, the standard deviation ellipse of the urban O3 concentration covered the entire eastern part of mainland China. Overall, the geographic center of ozone pollution has a tendency to move to the south with the time variation. The interaction between sunshine hours and other factors (precipitation, NO2, DEM, SO2, PM2.5) significantly affected the variation of urban O3 concentration. In Southwest China, Northwest China, and Central China, the suppression effect of vegetation on local O3 was more obvious than that in other regions. Therefore, this study clarified for the first time the migration path of the gravity center of the urban O3 pollution and identified the key areas for the prevention and control of O3 pollution in mainland China.
Parenting in Cerebral Palsy: Understanding the Perceived Challenges and Needs Faced by Parents of Elementary School Children
Authors: Guimarães Ana , Pereira Armanda , Oliveira André , Lopes Sílvia , Nunes Ana Rita , Zanatta Cleia , Rosário Pedro
Published: February 2023

Cerebral palsy (CP) can be considered the most frequent childhood physical disorder. The severity and type of dysfunction depend on the brain injury. Movement and posture are the most affected areas. CP is a lifelong condition, and parenting a child with this disorder brings additional challenges (e.g., dealing with grief) and needs (e.g., information). Identifying and characterizing their challenges and needs are pivotal to enrich the knowledge in this field and help draw more suitable support for parents. Interviews with 11 parents of children with CP attending elementary school were conducted. The discourse was transcribed, and a thematic analysis was performed. Three themes emerged from the data: (i) challenges of parenting a child with CP (e.g., internal challenges), (ii) crucial needs for parents to cope with a child with CP (e.g., information), and (iii) the intersection between challenges and needs of parents of children with CP (e.g., unawareness). Regarding the challenges and needs characterization, lifespan was the most frequent period of child development, and the microsystem was the context of life most reported. The findings may inform the design of educational and remediation interventions to support families of children with CP attending elementary school.