bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of Bedside Ultrasound for Ophthalmic Evaluation in a Case of Traumatic Brain Injury: A Case Report
Authors: Karki Bipin , Shrestha Ninadini , Neupane Ashru , KC Hony , Shrestha Pramesh Sunder , Acharya Santosh
Published: December 2023

Background: Ophthalmological examination is an important aspect of the neurological assessment in a patient with traumatic brain injury.  However, significant periorbital swelling can make direct visualization of the pupils difficult. Ultrasonic examination can be a valuable bedside tool when direct visualization fails.
Case: A case of a seven-year female child who had presented with a history traumatic brain injury is reported here.
Observations: The periorbital swelling prevented the direct visualization of the eyes. Bedside evaluation with a multipurpose ultrasound (USG) was used to monitor the pupillary diameter (PD) and the consensual pupillary light reflex (PLR) at regular intervals. The PD was measured in the B-mode while the PLR was monitored in M-mode of the USG. The optic nerve sheath diameter (ONSD) was also monitored as a correlate of intracranial pressure (ICP).
Conclusion: Ophthalmic evaluation of PD and PLR can be easily and objectively done on the bedside using USG especially in cases where the direct visualization of the pupils is difficult due to injuries and swelling of the periorbital tissues. Furthermore, ONSD measurements can also be done to monitor the changes in the ICP.
Outcome of Optical Keratoplasty for Corneal Scar due to Infective Keratitis
Authors: Bajracharya Leena
Published: December 2023

Introduction: Corneal opacity is an important cause of blindness in developing countries.
Objectives: This study analyzes optical keratoplasty performed for corneal opacity due to infective keratitis.
Materials and methods: This is a retrospective study of all consecutive cases of optical keratoplasty performed between 2011 and 2014 (four-year period) for healed infective keratitis. Cases with less than two months’ followup were excluded during outcome evaluation. Comparison was made between keratoplasty for Microbial and Viral (herpetic) Scar.
Results: Ninety-three eyes of 93 patients were enrolled. Fifty-nine (63.4%) were male. Average age of patients was 38.9±19.5 years. Average donor endothelial cell count was 2713±434.5 cells/mm2. Fifty-four (58%) corneal scars were due to microbial keratitis and others were herpetic. Eighty-five (91.4%) had undergone penetrating keratoplasty. Eighty-eight (94.6%) cases were included for outcome analysis. Average follow-up duration was 37±27.5 months. Fifty-two (59%) had clear graft at their last visit. Twenty-three (26.1%) grafts had endothelial failure and 13 (14.7%) grafts failed due to late onset keratitis. Twenty-five (28.4%) had vision of ≥6/18. Rejection occurred in 24(27.2%) and glaucoma in 11(12.5%). Post-operatively viral keratitis in the graft occurred significantly more inViral Scar Group (38.6%, n=15) than in Microbial Scar Group (5.5%, n=3). But there was no significant difference in graft clarity, rejection, vision and secondary glaucoma between the two Groups.
Conclusion: Outcome of keratoplasty for post-infectious scars was found fairly satisfactory. Although occurrence of viral keratitis was higher in case of keratoplasty done for Viral Scars, the final result was similar to that of microbial scar.
Clinical Characteristics of Patients with Glaucoma Presenting to Bharatpur Eye Hospital: An observational study - Are we doing enough?
Authors: KC Binita
Published: December 2023

Not available.
Isolation, and characterization of Cladosporium alboflavescens for Acetaminophen biodegradation
Authors: Meghmala Waghmode  , Neha Patil
Published: December 2023

One of the pharmaceutical micropollutants with a detrimental effect on the environment is paracetamol. Mycoremediation of the pollutants is a widely accepted concept based on cost and eco-friendly nature. Fungi isolated from pharmaceutical industry effluent have been used to target the biodegradation of paracetamol. The fungus’s internal transcribed spacer (ITS 1) sequencing matched that of Cladosporium alboflavescens (GenBank accession number OQ977005) by 99.81%. The strain demonstrated 89% biodegradation of paracetamol (1000 ppm) after 96 hours of incubation with 4-aminophenol as the predominant biodegradative metabolite, according to the spectrophotometric and high-performance liquid chromatographic analysis. The half-life of 1.44 days and simple first order kinetics were proposed by the Computer Assisted Kinetic Evaluation (CAKE) tool used to examinethe biodegradation kinetics.

Key words: Acetaminophen, 4-aminophenol, Cladosporium, Mycoremediation
Real-Time Subtitle Generator for Sinhala Speech
Authors: R.V.P.S. Akesh  , R.G.N. Meegama
Published: December 2023

In today’s digital era, the significance of speech recognition technology cannot be overstated as it plays a pivotal role in enabling human-computer interaction and supporting various applications. This paper focuses on the development of a real-time subtitle generator for Sinhala speech using speech recognition techniques. The CMUSphinx toolkit, an open-source toolkit based on the Hidden Markov Model (HMM), is employed for the implementation of the application. Mel-frequency cepstral coefficients (MFCC) are utilized for feature extraction from the given ’wav’ format recordings. The paper places significant emphasis on the importance of a real-time subtitle generator for Sinhala speech and explores the existing literature in the field. It outlines the objectives of the research and discusses the achieved outcomes. By fine-tuning hyperparameters to enhance the recognition accuracy of the system, impressive results of 88.28% training accuracy and 11.72% Word Error Rate (WER) are attained. Thesignificance of this research is underscored by its methodological advancements, robust performance metrics, and the potential impact on facilitating seamless interactions and applications in the Sinhala speech domain.

Keywords: Speech recognition, Real-time, Subtitle, CMUSphinx, Open source, Hidden Markov Model, Mel-frequency cepstral coefficients, ’wav’, Accuracy, Word Error Rate
High-frequency Noise Removal of Audio Files using Daubechies Wavelet Transform
Authors: N. K. Kularathne  , M. M. P. M. Fernando  , J. M. U. T. D. Jayasinghe
Published: December 2023

In general, audio signals are contaminated with various types of noise. This paper presents a novel signal processing method developed for high-frequency noise elimination using wavelet transforms. As a continuation of a previous study that used Fourier transform for noise removal in audio files, in this study Daubechies wavelets were used to reduce computational complexity and achieve better noise reduction performances. Compared to the Fourier transform, the Daubechies wavelet transform method removes the noise in each signal while preserving its vital characteristics. The suitable level of the Daubechies wavelet for noise removal in each channel was obtained using a trial-and-error approach. It was identified that the ideal range for the level of the Daubechies wavelets for noise removal is between 17 and 20. Moreover, unlike the Fourier transform, the Daubechies wavelet transform demonstrates a proficient capacity in eliminating noise from data point that lies completely outside the rest in the audio data set. Wolfram Mathematica 12.3 software package was used to complete this research. This method can be applied toconserve vintage audio recordings originally recorded in cassettes and spools.

Keywords: Digital Signal Processing, Wavelet Transforms, Daubechies Wavelet Transform, Fourier Transforms, Noise Removal
Synthesis and Characterization of Novel Diethylenetriamine Based Sulfonamide Ligands and Their Bidentate Platinum(II) Complexes Toward Anticancer Drug Leads
Authors: Theshini Perera  , Dinithi Kaluthanthiri  , Umapriyatharshini Rajagopalan  , Sameera Samarakoon  , Laksiri Weerasinghe  , Inoka C. Perera
Published: December 2023

Diethylenetriamine (dienH) is one of the most biologically compatible chelate frameworks. Its hydrophilic amine moiety was functionalized via N-sulfonylation with sulfonyl chloride to produce two novel ligands; N(SO2)(bzd)dienH (L1) and N(SO2)(4-Mebip)dienH (L2) and two reported ligands; N(SO2)(1-nap)dienH (L3) and N(SO2)(2-nap)dienH (L4). Treatment of cis-Pt(DMSO)2Cl2with L1, L2, L3 and L4 afforded four novel neutral complexes [Pt(N(SO2)(bzd)dienH)Cl2] (C1), [Pt(N(SO2)(4-Mebip)dienH)Cl2] (C2), [Pt(N(SO2)(1-nap)dienH)Cl2] (C3) and [Pt(N(SO2)(2-nap)dienH)Cl2] (C4) respectively. All synthesized compounds were characterized by 1H NMR, UV-Vis, FTIR and fluorescence spectroscopy. Aliphatic diethylenetriamine protons of the ligands appeared in the 3.00 -2.30 ppm region in 1H NMR spectra recorded in DMSO-d6. Upon complexation, the appearance of two broad NH peaks between 5.00 -7.00 ppm region and another broad peak between 7.00-8.00 ppm confirmed the bidentatedenticity of the ligands vs tridentate. The formation of metal complexes was further supported by FTIR spectra in which the S-N stretching band for the metal complexes appears at lower wavenumbers compared to that of the corresponding free ligands. Emission spectra were recorded in methanol and intense fluorescence properties were observed in the 331-364 nm range for the ligands, whereas the corresponding Pt complexes showed quenched fluorescence. In vitro cytotoxic effects were investigatedusing sulforhodamine B assay, where L2 (< 10 μg/mL) demonstrated increased levels of cytotoxicity followed by C2 (< 25 μg/mL) and C4 (< 50 μg/mL) to non-small cell lung cancer cells in dose and time-dependent manner, with less or no cytotoxic effects to normal lung cells tested. Among the compounds tested, C1 and C3 displayed comparatively lower but more potent cytotoxic effects on lung cancer cells. Notably, these compounds did not exhibit any toxicity towards normal cells. Thus, they hold promise as lead compounds for the development of chemotherapeutic agents targeting lung cancer.

Keywords: Platinum, Sulfonamide, Biphenyl, Benzodioxan, aphthalene
AVALIAÇÃO “IN VITRO” DO AMINOFOSFITO DE COBRE® EM FUNGOS FITOPATOGÊNICOS
Authors: Maciel Terra Leonardo
Published: December 2023

Os fosfitos são compostos à base de fósforo que atuam como indutores do sistema de defesa das plantas, ou são diretamente tóxicos aos patógenos, constituindo uma das alternativas no manejo integrado de doenças. Este trabalho avalia o efeito in vitro do Aminofosfito de Cobre® (Ubyfol) sobre os  fungos fitopatogênicos: Sclerotinia sclerotiorum, Exserohilum turcicum, Fusarium oxysporum, Stenocarpella maydis. O delineamento foi inteiramente casualizado, realizado em duplicata, com 5 tratamentos e 5 repetições, constituídos das doses de 0; 0,25; 0,5; 0,75 e 1,0 L.ha-1 de Aminofosfito de Cobre®, acrescidas em meio de cultura BDA. O experimento foi realizado no Laboratório de Microbiologia das Faculdades Associadas de Uberaba (FAZU), mensurando-se o Índice de Velocidade de Crescimento Micelial (IVCM) e o Percentual de Inibição de Crescimento (PIC) micelial dos fungos. A dose de 0,25 L.ha-1 reduziu significativamente o IVCM dos fungos S. sclerotiorum e S. maydis, e apresentou valores consideráveis de PIC micelial. Os fungos E. turcicum e F. oxysporum apresentaram redução significativa do IVCM apenas a partir da dose 1,0 L.ha-1. Esse foi o primeiro estudo com a avaliação do Aminofosfito de Cobre® no controle dos fungos citados. Os resultados indicam que o uso desse produto apresenta efeito direto sobre determinados microrganismos causadores de doenças em plantas.
POTENTIAL IMPACTS OF CLIMATE CHANGE ON AGRICULTURAL PRODUCTION IN THE LONG XUYEN QUADRANGLE, VIETNAMESE MEKONG DELTA
Authors: Dinh Tran The , Nhan Nguyen Thi Thanh , Nguyen Ho
Published: December 2023

Climate change and its impacts have become a serious and concerning global issue. The Vietnamese Mekong Delta, is identified as one of the deltas most adversely affected by climate change. This study aims to assess the potential impacts of climate change on seven major agricultural production systems in the Long Xuyen Quadrangle region within the Vietnamese Mekong Delta. Utilizing the Analytic Hierarchy Process (AHP) in conjunction with calculating climate change impact indices, the research classifies the degree of climate change impact on agriculture, aquaculture and forestry. The study results indicate that different agricultural production systems will experience varying impacts from climate change. For rice cultivation, flooding and drought are identified as the factors with the highest impact. Factors such as temperature increase, changes in rainfall and salinity intrusion have the most significant effects on aquaculture. In contrast, cultivated and natural forests in the research area are less affected by climate change. This assessment outcome could be highly valuable for policymakers in developing local agricultural development plans.
Keywords: climate change effects; land use; rice cultivation; saline intrusion.
 
Impacto potencial das alterações climáticas na produção agrícola no Quadrilátero Long Xuyen, Delta vietnamita do Mekong
 
RESUMO: As alterações climáticas e os seus impactos tornaram-se uma questão global séria e preocupante. O Delta vietnamita do Mekong é identificado como um dos deltas asiáticos mais afetados pelas alterações climáticas. Este estudo visa avaliar os impactos das alterações climáticas em sete grandes sistemas de produção agrícola na região do Quadrilátero Long Xuyen, no Delta do Mekong, Vietnã. Utilizando o Processo de Hierarquia Analítica (AHP), em conjunto com o cálculo dos índices de impacto das alterações climáticas, a investigação classifica o grau de impacto das alterações climáticas na agricultura, aquicultura e silvicultura. Os resultados do estudo indicam que diferentes sistemas de produção agrícola sofrerão impactos variados das alterações climáticas. Para o cultivo do arroz, as inundações e a seca são identificadas como os fatores de maior impacto. Fatores como o aumento da temperatura, as mudanças nas chuvas e a intrusão de salinidade têm os efeitos mais significativos na aquicultura. Em contraste, as florestas cultivadas e naturais na área de investigação são menos afetadas pelas alterações climáticas. O resultado desta avaliação poderá ser altamente valioso para as decisões políticas no desenvolvimento de planos de desenvolvimento agrícola local.
Palavras-chave: efeitos das alterações climáticas; uso da terra; cultivo de arroz; intrusão salina.
Attitudes of Palestinian Arabs towards Jewish Zionism during and after the reign of Sultan Abdulhamid II
Authors: GÖKMEN Murat
Published: December 2023

With the end of the Ottoman Empire in Bayt al-Maqdis a new page in history was being turned, ending centuries of peace in the Holy Land. This study concentrates on Palestinian Arabs and their attitudes towards Jewish Zionist settlement and their land purchase activities in Palestine, particularly under the British occupation. There are two divergent ideas concerning Palestinian and Jewish Zionists relations. While some scholars claim that Arab Muslims were passive and submissive towards Jewish Zionists and they did not put forward reactionary attitude towards Jewish Zionists and they even further state that those Arabs sold their lands to them willingly and earned huge sums of profit and hence they were contented with Zionist settlement. However, contrary to this claim evidence shows Arab Palestinians helped and supported the Ottomans against Jewish Zionism in restricting Zionist settlement and land purchase activities in Palestine. In this respect, this study argues that Palestinian Arab Muslims from the outset foresaw expansionist Zionists and put forward their resistance in different means. They clearly did their best to stop the Zionist influx and thus altered the attitude of the British Mandate. Therefore, throughout the study it can be clearly seen that even after the end of the Ottoman rule in the region, Palestinian Arabs tried their best to preserve their presence and status in Palestine against the British and Jewish Zionists.
Kitap Tanıtım/ Eyyûbiler: Kültür ve Medeniyet
Authors: GÜNEŞ Halil Rahman
Published: December 2023

Eyyûbî tarihi, İslâm coğrafyasında ve Batı dünyasında geniş bir çalışma alanı oluşturan dönemlerden birisidir. Türkiye'de de bu dönemle ilgili birçok çalışma bulunmaktadır. Ancak bu çalışmaların çoğu genellikle Selahaddin Eyyûbî dönemine odaklanmış ve klasik kronolojik bir bakış açısıyla hazırlanmıştır. Eyyûbî kültür ve medeniyeti hakkında ise çok sınırlı araştırma yapılmış, bu durum konunun gölgede kalmasına sebep olmuştur. Bu eksikliği gidermek amacıyla alanda uzman akademisyenlerin bir araya gelerek çıkardığı "Eyyûbîler: Kültür ve Medeniyet" isimli esermevcut alanda önemli bir boşluğu doldurmaya namzettir.
Validation of calcium (Ca) analysis in dolomite fertilizer using atomic absorption spectrophotometer (AAS)
Authors: Agustiyar Fandika , Umar Wakhid Khoirul , Guritno Agung
Published: December 2023

The method of determining calcium (Ca) in dolomite fertilizer has been validated using atomic absorption spectrophotometer (AAS). Determining calcium (Ca) in dolomite fertilizer refers to the Indonesian National Standard (SNI) 02-2804-200. Based on the results of the calcium (Ca) test on dolomite fertilizer, the correlation coefficient (r) was 0.9949, and the % relative standard deviation (RSD) was 0.6472%, less than 2/3 CV Horwitz of 1.5963. The accuracy value is 100.30%, the precision value is 0.6471%, the detection limit for the LOD method is 0.2817, the LOQ is 0.9390, and the instrument detection limit is LOD 0.1159 and LOQ 0.3864. This study shows that the determination of calcium (Ca) in dolomite fertilizer using the SNI method using the Atomic Absorption Spectrophotometer (AAS) can be used with valid results.
Analysis of lowland rice peat land in Mampai Village, Kapuas Murung District, Kapuas-Kalimantan Central District
Authors: Sunaryati Revi , Wahib Muhaimin Abdul
Published: December 2023

Central Kalimantan is a province where the agricultural sector is still the basis for economic cohesion. Mampai Village, Kapuas Murung District, Kapuas District, Central Kalimantan is a peatland rice field. Peat soil is wet soil and stores a lot of acid, so it is not easy to use or to grow crops. The purpose of this study was to determine the general description of lowland rice farming held in Mampai Village and to determine the amount of lowland rice income and its contribution to the total income of lowland rice RTP in Mampai Village, Kapuas Murung District, Kapuas District, Central Kalimantan Province. The results of descriptive analysis of the general description of farming in rice fields in Mampai Village, Kapuas Murung District, Kapuas Regency have implemented farming intensification technology well where farmers have implemented a cropping pattern 2 times a year, namely MT I and MT II with an average cultivated area of 2.40 ha. pe MT. The results of the analysis of lowland rice income obtained forone year by farmers amounted to Rp. 36,355,109 and contributes 74.93%, this shows that the role of lowland rice farming for farmers in Mampai Village is very important, thus it can be said that rice field rice farmer households in Mampai Village, Kapuas Murung District, Kapuas District, Central Kalimantan, are categorized as not poor.
Water availability analysis of Walanae River
Authors: Lias Syamsul Arifin , Assegaf A , Sakka Sakka , Paharuddin Paharuddin , Syamsuddin E
Published: December 2023

The Walanae Watershed plays an essential role as a water provider for irrigation and industry in the central part of South Sulawesi Province, Indonesia. The Walanae River flows through Enrekang, Soppeng, and Bone Regencies. This paper describes the availability of water in the Walanae watershed. Water discharge of the Walanae river recorded at Tampangeng station from 2000 to 2014 is analyzed using descriptive statistics to obtain a flow duration curve. The calculation results show that the available discharge is quite extensive throughout the year with a range of 16.5 m3.s–1–316 m3.s–1, and an average of 138 m3.s–1. The minimum discharge generally occurs from September to November, while the peak discharge generally occurs in January and July. The results show that water availability for 9, 10, 11 months, and all years are:  92.2 m3.s–1, 83.4 m3.s–1, 66.3 m3.s–1, and 15.8 m3.s–1, respectively.
Effect of temperature and drying time on physicochemical of beetroot (Beta vulgaris L. var. Rubra L.) flour
Authors: Prabowo Ulya Sarofa , Aprilia Rina
Published: December 2023

Beetroot is a food source that is rich in nutrient value, including carbohydrates, minerals, vitamin C and betalains as a source of antioxidants. The high-water content causes the beetroot to be easily damaged, therefore a suitable method, is needed to preserve it. Like being processed into intermediate goods such as flour. The aim of this research was to determine the effect of temperature and drying time on the chemical characteristics and color of beetroot flour. This research used a completely randomized design (CRD) in factorial with two factors, namely the drying temperature range (50 °C, 60 °C, and 70 °C) and the drying time range (6, 7, and 8 hours). ANOVA and DMRT advanced test were used to test the resulting data.  The results showed that the best treatment was obtained from sample treated a drying temperature of 50oC and a drying time of 6 hours, the yield value was 13.53%, with water content of 12.61%, ash 2.65%, fat 0.73%, protein 11, 16%, carbohydrate 72.85%, antioxidant activity 69.80%, anthocyanin 69.81 mg.100 g–1, Vitamin C 31.92 mg.100 g–1, color intensity L* 15,825, a* 7.82, b* 2.78.
Value added and business feasibility analysis of chili sauce products in Banggae District, Majene Regency
Authors: Putri Dwi Ahrisa , Kaimuddin Kaimuddin , Mas’udin Gita Afmiranti
Published: December 2023

SMEs are expected to grow and compete in products development that have value added to encourage economic sustainability. The value added provided a value to maintaining and enhancing the quality of agricultural products can also add to its economic value by processing it into a product such as chili sauce products. This study aims to find out how much value added is given and the value of business feasibility. The research sample was determined deliberately with the consideration of choosing the entire chili sauce business unit as many as 7 SMEs in Banggae District, Majene Regency which processes chili sauce and has fresh chili mixture ingredients. The data analysis used is a value-added analysis of the estimated value added of the product, labor rewards, rewards for capital and management while the R /C ratio is to see the profit of a business to the costs used and to find out whether the business is feasible. The results showed that there is a value added provided from chili processing in one production is Rp. 356,776.7 / kg so that it can increase the difference between the input price and the selling price of the output which indicates that processing chili into a product can be of high value. The chili sauce business has been efficient because the R /C ratio value of more than one, which is 1.63, means that it can be concluded that this business feasible to be developed.
Discovering the socio-economic migrant performance on illegal logging activities for deforestation problem solving in Banyuasin Regency, South Sumatera (case study of Sungai Buring traditional village)
Authors: Adriani Dessy , Purbiyanti Erni , Huanza M. , Damayanthy Dini
Published: December 2023

It is often excluded from the handling of illegal logging and deforestation is the release of the socio-economic aspects in problem solving deforestation and forestry development. The purpose of this study was to: 1. Identify the socio-economic characteristics of the migrant who become illegal loggers, 2. Analyze the amount of illegal loggers' income and its allocation to the consumption, and 3. Develop a strategy to overcome illegal logging and forest deforestation based on the socio-economic characteristics of the logger. The analysis showed that socio-economic conditions of the migrant who become illegal loggers illustrates that they are still a low level of education and have productive age. Income earned Rp 4,301,211.00/year/family, lower than the income of Rp 33,070,945.00/year/family after migrating. Income get from illegal logging are Rp 13.087.945/year/family. Average migrant allocates 60.81 % of its total income for consumption, and the remaining 39.19 % is allocated to farming and non-farming activities. This study suggests that there should be an increase in revenue breakthrough in the area of origin to be able to suppress the migration process becomes illegal loggers to other areas. Low income is the core problem of farmers to migrate. Required two basic designs: (1) social engineering with community and (2) technical engineering in the direction of the multiproduct and multifunctional forest benefits to overcome the problems of forestry in the long run.
PSYCHOSOMATIC MANIFESTATIONS OF MILITARY PSYCHOTRAUMA
Authors: Kolіadenko Nina V. , Bachurina Nadiia O. , Zhyvaho Khrystyna S. , Shopsha Mykola M. , Shopsha Olena L.
Published: December 2023

Introduction. War is a super-powerful extreme event that causes adaptive capacity to decline. The need for a clearer understanding of the specifics of war psychotrauma and its clinical consequences for all components of human health determines the relevance of the topic of this study.
The aim of the work is to study the peculiarities of psychosomatic relationships in persons with the consequences of war psychotrauma.
Materials and methods. The experimental study group consisted of 32 patients from the number of temporarily displaced persons, the control group – 34 patients who did not change their place of residence during the entire period of the full-scale war. The diagnosis was aimed at identifying neurotic, stress-related and somatoform disorders, according to the rubric (F40-F48) of the ICD-10. Assessment of the somatic condition was carried out on the basis of analysis of anamnestic data, clinical examination of the patient and indicators of laboratory tests. Psychodiagnostic methods were used to assess the mental states of patients (Clinical Questionnaire for the Detection and Assessment of Neurotic States; Methodology for the express diagnosis of neurosis by K. Heck and H. Hess; Questionnaire SAN (Mood, Activity, Mood); Methodology for the diagnosis of Taylor's anxiety level; Self-assessment of mental states according to Eysenck; Ch. Spibleger's Reactive and Personal Anxiety Assessment Scale in the modification of Y. Hanin. Statistical processing of the research results was carried out in the Microsoft Excel program and with the help of the Social Science Statistics online calculator.
Results. As a result of the analysis of anamnestic data, clinical examination and analysis of laboratory tests, psychosomatic disorders were found in patients of both research groups: in 29 (90.63%) patients of the experimental group and in 26 (74.47%) patients of the control group.
Conclusions. It has been confirmed that a prolonged stressful extreme situation of a full-scale war causes the formation of negative mental states accompanied by psychosomatic manifestations, the formation of a closed vicious circle of a pathological psychosomatic process. A high close direct correlation was found between the level of reactive anxiety, autonomic disorders, well-being, activity, mood of patients and psychosomatic symptoms. The absence of a statistically significant difference in the risk of developing psychosomatic disorders as a result of war psychotrauma in temporarily displaced persons and those who did not change their place of residence was revealed.
HISTORICAL AND PSYCHOTHERAPEUTIC ASPECTS OF PENILE IMPLANTATION
Authors: Kornyenko Oleksii M. , Shcherbak Mariia O. , Nurimanov Kamil R.
Published: December 2023

Introduction. To date, despite significant progress in the field of erectile dysfunction (ED) pharmacotherapy, for a certain group of patients, the implantation of a penile prosthesis is the only possible way to return them to an active sexual life. To increase the satisfaction with the sexual life of men and their partners, the improvement of models of penile prostheses, which has its own history, is being carried out. In addition, in andrology, methods of psychotherapeutic correction of ED are introduced for both men and their partners.
The aim. To determine the influence of the type of penile implant and psychotherapeutic correction on the frequency of satisfaction of sexual partners.
Materials and methods. Out of 354 patients operated on by us, 80 men with severe organic ED and their sexual partners consented to participate in the study. Men underwent penile implantation. Participants were divided into two groups:
1st group – 40 couples in which men had a plastic implant installed;
The 2nd group – 40 couples in which men had a hydraulic implant installed.
Each group was divided into two subgroups. In subgroups 1a (20 couples) and 2a (20 couples), psychological counseling was given to both partners before and after the operation, in subgroups 1b and 2b no psychological counseling was given.
Results: Between subgroups 1b and 2b, patients whose psychological counseling was not performed, differences in the general satisfaction with sexual life in women were not observed, and it was observed in both subgroups in 65% of the patients' partners. Men of these subgroups were satisfied with their sex life after implantation in 80% and 85%, respectively.
In 95% of women after psychotherapeutic support (subgroups 1a and 2a), satisfaction with sexual life was noted, which was statistically significantly higher (Fisher's exact test, p < 0.05) than in women of subgroups 1b and 2b.
In men of subgroups 1a and 2a, this indicator corresponded to 90% and 95%, respectively. Dissatisfaction among partners in subgroups 1b, 2b, respectively, was 35%, among women after psychotherapeutic correction (subgroups 1a, 2a), 10% and 5%, respectively.
Conclusions. The obtained data show that satisfaction with sexual life in men does not depend on the implant model and psychological counseling. Unlike men, the frequency of satisfaction with sexual life in female partners after psychotherapeutic correction reaches 95%, which is statistically significant more than without it (р˂0.05).
IMPACT OF THYRONAMINE ANALOGUE ON LIPID PEROXIDATION IN THE BRAIN OF RATS
Authors: Fedorova Hanna , Velychko Nataliya , Bogatyrova Olena
Published: December 2023

Introduction. Thyronamines belong to agonists of TAAR1 - trace amine receptors in the brain. The mechanism of activation of the processes of autophagy and neuroplasticity under the action of a synthetic analogue of thyronamines – 4-(4-(2-aminoethoxy)benzyl)aniline is described. Since cerebrovascular disorders remain the most common among neurological diseases, the development and implementation of drugs with neuroprotective properties is considered a promising strategy for the treatment and rehabilitation of patients with ischemic stroke.
The aim of the study was to elucidate the effect of 4-(4-(2-aminoethoxy)benzyl)aniline on the activity of GPO, SOD and the dynamics of changes in the level of TBARS in the brain of rats after modeling focal ischemia by transient occlusion of the left middle cerebral artery.
Materials and methods. The 4-(4-(2-aminoethoxy)benzyl)aniline was synthesized. Changes in the activity of antioxidant enzymes and the accumulation of secondary LPO products that react with thiobarbituric acid (TBARS) in rat brain homogenates were observed after injection of the studied compound in different dosages, as well as 24 hours after modeling focal ischemia. A neurological deficit in experimental rats was detected by the Garcia scale and the vibrissae-evoked forelimb placing test.
Results. Compilation of data made it possible to find a strong relationship between the amount of the injected analogue and the growth of GPO activity in the neurons of healthy animals. In 80% of rats, occlusion of the middle cerebral artery induced evident sensorimotor disorders. 24 hours after the administration of a synthetic analogue of thyronamine in the homogenates of the affected left hemisphere, the activity of glutathione peroxidase significantly increased, and the content of TBARS decreased, and a tendency to activation of SOD was also observed.
Conclusions. The obtained data indicate a positive effect of 4-(4-(2-aminoethoxy) benzyl) aniline on antioxidant enzymes in the intact rat brain and after modeling of focal ischemia, which is the basis to continue research for the purpose of finding long-term neuroprotective effects.
SELECTED ASPECTS OF THE CURRENT STATE OF HEALTH OF THE MALE POPULATION OF UKRAINE
Authors: Lytvynova Liubov A. , Hrechyshkina Nataliia V. , Donik Olena M. , Artemchuk Liudmyla I. , Bibyk Inessa G. , Orlychenko Kateryna V.
Published: December 2023

The aim of the study. To investigate certain aspects of the state of health of the male population of Ukraine in the period 2014-2021; justify the value of a separate analysis of men's health; to determine the need for personalized accounting of the health status of persons who took part in military operations, in particular men.
Materials and methods. The research materials were official statistical data from the reports of the State Statistics Service, the Center for Medical Statistics of the Central Health Service of the Ministry of Health of Ukraine for 2014–2021, the National Cancer Registry of Ukraine, the Institute of Health Metrics and Evaluation (IHME, USA) on the global burden of diseases, data individual sociological studies. The female population of Ukraine served as a comparison group.
Results. The dynamics of the state of health of the male population by individual indicators (mortality, average life expectancy, morbidity, disease burden) in recent years compared to the female population were analyzed. It was established that the health of the male population has negative trends and is inferior to the vast majority of the relevant indicators of the health of the female population. In addition, the severe consequences of military operations, men's lack of attention to their own health, particularly reproductive health, and an unhealthy lifestyle significantly worsen the health of the male population. An in-depth study of the health of the male population is needed to understand its specific needs in health care services, to develop prevention, treatment and rehabilitation programs.
Conclusions. Against the background of the deterioration of the health of the male population, especially during the war, it is necessary to provide him with all kinds of support, to improve the quality and availability of various types of medical care, to introduce personalized records of the health of combatants (military and civilians), as well as children of war.
MOLECULAR MECHANISMS OF NOCICEPTION IN CHRONIC PROSTATITIS
Authors: Gorpynchenko Igor I. , Nurimanov Kamil R. , Nedogonova Olena A.
Published: December 2023

Introduction. The need to understand the pathophysiology of prostatitis is determined by its prevalence, usually chronic progressive course, significant impact on quality of life, fertility and sexuality. The modern arsenal of medicines allows us to achieve a clinically significant effect. Along with this, non-pharmacological methods are widely used to increase the effectiveness of treatment. However, despite significant successes in the treatment of prostatitis, the problems of insufficient efficiency remain unsolved by modern urology, and it is extremely difficult to help these patients. Understanding the pathophysiology of the disease has always been the key to successful diagnosis and treatment. That is why it is important to determine the mechanisms of development of painful manifestations of prostatitis.
The aim. To describe the main molecular mechanisms of tissue damage reception, in particular of the prostate gland, which are perceived as pain sensations.
Materials and methods. An evaluation of modern literature devoted to the mechanisms of creation of nerve impulses due to damage and inflammation of the prostate gland was carried out. The search was conducted in the MEDLINE and databases of the National Library of Ukraine named after V.I. Vernadsky.
Results. The main molecular mechanisms of nociception in chronic prostatitis have been determined. A review of modern literature devoted to the study of pain mechanisms as a biologically significant signal of damage at the molecular level of reception is presented. Attention is focused on the features of nociception in prostatitis, its connection with the production of inflammatory mediators, possible mechanisms of hyperalgesia and allodynia.
As a result of stress and tissue damage, the production and release of inflammatory mediators such as interleukins, interferon, prostaglandins, bradykinin, adenosine triphosphate, protons and nerve growth factor increase. These mediators activate pain receptors located on nerve endings and are ion channels of various types: transient receptor potential, acid, purinergic, and potassium ion leak channels.
Conclusions. The presented literature data describe the mechanisms of nociception, hyperalgesia and allodynia in chronic prostatitis, the understanding of which can be the basis for the development of new methods of diagnosis and treatment.
Pendampingan Membaca Al-Qur’an Secara Tartil (Ilmu Tajwid) Berbasis Macro Media Flash untuk Anak-Anak Desa Sungai Petai Kabupaten Kampar
Authors: Harahap Musaddad , Firdaus Firdaus , Putra Ary Antony , Alfitri Alfitri , Rambe Romaito
Published: December 2023

Permasalahan kegiatan PkM ini adalah ditemukannya fakta rendahnya kemampuan dan motivasi belajar ilmu tajwid anak-anak muslim. Idealnya sebagai seorang muslim harus mengerti bahwa ilmu tajwid merupakan ilmu yang wajib dipelajari, karena dengannya seseorang lebih potensial dalam menghayati, memahami, dan menginternalisasikan nilai-nilai agama. Untuk meningkatkan kemampuan ilmu tajwid bisa dengan menggunakan media. Media yang akan digunakan adalah macro flash. Tujuan PkM ini adalah untuk meningkatkan kemampuan membaca Al-Qur’an secara tartil (ilmu tajwid) bagi anak-anak muslim. Metode PkM ini adalah berbentuk pendampingan membaca Al-Qur’an secara tartil (ilmu tajwid) berbasis macro media flash untuk anak-anak di desa Sungai Petai. Dalam pelaksanannya, materi ilmu tajwid sudah didesain dalam macro media flash (by utilization) dan dipresentasikan. Pengumpulan data menggunakan pre test dan post test. Analisis data menggunakan persentase. Sasaran PkM adalah anak-anak mengaji. Hasil dari PkM ini adalah meningkatnya kemampuan membaca Al-Qur’an secara tartil (ilmu tajwid) anak-anak. Peningkatan itu terlihat dari perbandingan persentase hasil uji post test dengan pre test pada lima soal yang diberikan. Soal pertama, saat pre test jawaban anak-anak yang benar 60%. Pada saat post test mencai 100%. Soal kedua, jawab yang benar 70%, sedangkan pada saat post test 100%. Soal ketiga, 43,33%-96 dan saat post test 66%, Soal keempat, yang benar 56,66%, saat post test 100%. Soal kelima, yang benar 50%, sedangkan pada saat post tes sudah mencapai 100%. Hasil PkM ini sangat penting untuk dijadikan sebagai referensi, terutama jika ingin melakukan kegiatan pendampingan yang sama.
Pendampingan Belajar Sebagai Upaya Penanganan Learning Loss Pasca Pandemi Covid-19 Bagi Siswa SD Negeri 2 Lepar Pongok
Authors: Fahlevi Mahfudz Reza , Hilhamsyah Hilhamsyah
Published: December 2023

Pandemi Covid-19 memberikan dampak yang luar biasa bagi Indonesia di berbagai sektor, salah satunya di sektor pendidikan. Situasi pembelajaran di sekolah pun terpaksa dibatasi dan belajar daring, begitu pula yang terjadi di Desa Tanjung Sangkar Kecamatan Lepar Pongok sehingga siswa mengalami Learning Loss. Oleh sebab itu, mahasiswa KKN-MB IAIN SAS Bangka Belitung mengadakan program bimbingan belajar dengan berbagai metode menarik yang ditujukan bagi siswa SD Negeri 2 Lepar Pongok. Tujuannya, agar dapat meningkatkan prestasi belajar siswa dengan adanya bimbingan belajar. Pola yang digunakan dalam pengabdian kepada masyarakat ini mengacu pada model Asset Based for Community Development (ABCD) dengan teknik pengumpulan data berupa observasi, dokumentasi, dan respons angket para guru yang telah membersamai mahasiswa KKN. Analisis data menggunakan teknik deskriptif kualitatif dari penjabaran hasil observasi dan deskriptif kuantitatif dari respons angket. Hasil dari pengabdian ini berjalan dengan baik, tingkat literasi, numerasi dan prestasi siswa makin membaik. Dapat disimpulkan bahwa tingginya antusias siswa ketika belajar dengan metode yang menyenangkan dan juga didukung dengan berbagai respons positif dengan angka persentase yang tinggi dari para guru melalui angket.
Edukasi Guru SMPN 4 Kamal terkait Gaya Belajar Siswa Berbasis Kearifan Lokal
Authors: Risnasari Medika , Adhani Dwi Nurhayati , Mayangsari Dewi , Dellia Prita , Rozan Afrian , Dharmasaputra Adam , Firdausiyah Jannatul , Nariyono Nina
Published: December 2023

Guru adalah sosok yang penting di dalam proses pembelajaran. Guru sebagai fasilitator serta pendidik yang memberikan pembelajaran di kelas. Banyak faktor yang diperlukan dalam keberhasilan pembelajaran di kelas, salah satunya pemahaman tentang gaya belajar siswa. Pembelajaran di kelas lebih lancar jika guru dapat memahami gaya belajar siswa. Tujuan dari pengabdian masyarakat ini adalah memberikan seminar kepada guru di SMPN 4 Kamal tentang gaya belajar siswa berbasis kearifan lokal. Kearifan lokal dijadikan sebagai kerangka dalam pembelajaran siswa SMPN 4 Kamal. Metode pelaksanaan kegiatan pengabdian ini meliputi beberapa tahapan, yaitu observasi, pelaksanaan dan evaluasi. Kegiatan pengabdian diikuti oleh 20 orang peserta dari guru SMPN 4 Kamal. Tolak ukur dari keberhasilan seminar dilakukan dalam bentuk soal pretest dan posttest dari pemahaman materi yang disampaikan narasumber. Hasil yang didapat dalam pengabdian ini yaitu peningkatan pemahaman guru terhadap gaya belajar dengan rata-rata semula 66.5 menjadi 91.5 serta peningkatan pemahaman tentang kearifan lokal dengan rata-rata semula 70 menjadi 89.
Pascal: «une trace / la trace» in the concept of man in postmodern French philosophy
Authors: Kutsepal Svitlana
Published: December 2023

The article reconstructs the image of man in French postmodern philosophy of the second half of the twentieth century. The formation of this image is considered in relation to Michel Foucault's concept of sciences, as well as to the concept of schizoanalysis formulated by Gilles Deleuze and Felix Guattari. The author emphasizes that the key features of this image of a man are: (1) objectivity (modern culture makes a man not only a subject but also an object of science; therefore, the subject is presented not as a pure cognitive instance but also as a finite man limited in each specific historical epoch to specific forms of body, needs, and language); (2) emancipation as the content of freedom (a truly free person is seen as having left the sphere of existence as a machine – a set of functions). The author also notes that in the image of man associated with French postmodern philosophy, we can see a "trace" of Pascal's ideas about the duality of man and the impossibility of reducing him to any single aspect of his nature and existence, including rational or animal ones.
The phenomenon of B. Pascal in the European context: a view from the shore of historico-philosophical Ukrainian studies
Authors: Horskyi Vilen
Published: December 2023

The article is devoted to the problem of belonging of Ukrainian philosophy to the European tradition. The author states that Pascal's doctrine is non-ratio-centered and, therefore, does not correspond to the leading trends of European modern philosophy. At the same time, this doctrine is considered to be one of the most important for the development of the Modern tradition (including contemporary discussions between postmodernist and communicative philosophy thinkers). Thereafter the author concludes that modern philosophy is at least not monistic. The same non-monistic nature is also evident in the European history of ideas before the 17th century: the cleavage between Athens and Jerusalem, Latin and Greek theology, etc. This non-monism is manifested in the existence of at least two defining trends in European philosophy: the rational-centered one and the one that prefers a cordial attitude to the world and an approach of an intellectual contemplation. At the same time, the author notes that with the transition to lower levels of generalization, this dualism will increasingly appear to be a true pluralism of the European intellectual tradition. Based on the recognition of the content originality of national philosophies, the author attributes Ukrainian philosophy primarily to the second of the outlined trends. On the basis of the dominance of cordocentric orientations in Ukrainian philosophy, he rejects the arguments that interpret Ukrainian philosophy as fundamentally non-European.
The philosophy of B. Pascal and modern Christian theology. Towards an assessment of Christianity's adaptive capabilities in the postmodern socio-cultural context
Authors: Pronyakin Volodymyr
Published: December 2023

Author claims that Western theology must turn to Pascal's religious-philosophical legacy in order to find identification normatives that can ensure the cultural-adaptive stability of Christian identity. Such an approach is justified by a number of specific features of Pascal's philosophy: (1) existential character of thought; (2) anthropological nature; (3) symbolism; (4) semiotically obvious authenticity of artefacts of religious experience. In the author's opinion, the most promising in this context would be to address (2), Pascal's symbolic metaphysics, which is determined by the predominant influence of the ethical on its ontological and epistemological aspects. However, in the author's opinion, in the polycentric and pluralistic cultural and sociogenic environment of postmodernity, the identificational adaptation of Christianity is not only a "final transition" to religious symbolism. It is also important that Christians effectively strive to preserve and constantly cultivate the ability to value-based worldview.
Metamorphoses of individualism in Modern political philosophy
Authors: Spasenko Natalia
Published: December 2023

The author, following Niklas Luhmann, interprets the opposition "individual-society" as one of the pillars to which the ideological content of modern society is anchored. The same can be said about political philosophy: no matter how we understand the term "society" (in terms of collectivism, communalism, or holism), individualism is always understood as something ontologically rooted, as a constitutive factor of political space. Despite the resistance of influential opponents, methodological individualism has not become either a historical relic or a synonym for professional incompetence. Attempts to overcome this resistance led to the realization of a speculative tendency – self-description, which, according to Luhmann, inevitably constitutes itself as an ideology. However, individualism in the Modernity did not manifest itself as a strategy of a particular "-ology", but as a practical, non-contemplative strategy of political philosophy. The author agrees with Peter Koslowski that the question of the nature of the opposition "individual-society" can be answered only hypothetically. After all, this duality appears as: (1) a product of the historical process of individuation; (2) the result of the development of social production, the transition to private property; (3) an initial property of conditio humana. In contrast to other epochs, Modernity was the only one to propose to exclude the will to the common from individual motivations, to monistically present the individual concept of the good as a desire for personal gain.