bluuebunny/crossref_metadata_2025 huggingface dataset:
Reasonable Fertilization Improves the Conservation Tillage Benefit for the Yield of Winter Maize in Rice-based Cropping System of Central Inner Terai of Nepal
Authors: Marahatta Santosh , Karki Tika Bahadur
Published: September 2022

To investigate the effects of fertilization, tillage, and their interaction on maize yield, an experiment on rice-maize was conducted on 2018/19 and 2019/20 at Agriculture and Forestry University (AFU), Rampur, Chitwan, Nepal. The experiment was in a split-plot with two establishment methods viz. (i) zero tillage followed after (fa) conventionally tilled dry direct seeded rice (ZT fa CT-DDSR) (ii) conventional tillage fa puddled transplanted rice (CT fa Pu-TPR) and four nutrient management practices, i.e. (i) recommended dose (100% RDF; 180-90-60 N-P2O5-K2O kg ha-1), (ii) Residue retention of rice crop @ 5 t ha-1 + 75% RDF (RR +75% RDF), (iii) Nutrient expert (NE) dose (150-50-90 N-P2O5-K2O kg ha-1), (iv) Rice residue @ 3.5 t ha-1 +75% RDF followed after brown/green manuring of Sesbania in rice (R+75% RDF fa BM/GM) and the treatments were replicated thrice. The data on yield and yield attributes were recorded and analyzed by R studio. Both crop establishment methods and nutrient management practices did not influence (p>0.05) the plant population, number of cobs per plant, number of grains per cob, thousand-grain weight, and sterility. The barrenness percentage was not significantly affected by the crop establishment methods but significantly (p>0.05) lower under residue retained treatments. Application of NE dose, sterility was significantly (p<0.05) reduced under ZT fa CT-DDSR. The average grain yield, straw yield, and harvest index (HI) were 6153 kg ha-1, 4547 kg ha-1, and 53.81% respectively. The two years average grain yield was statistically at par (p>0.05) for both crop establishment methods whereas application of NE dose, RR+75% RDF, and R+75% RDF fa BM/GM resulted in significantly (p<0.05) higher grain yield than obtained in the 100% RDF applied plots.  Maize planting on zero tillage followed after CT-DDSR was equally productive and the use of a nutrient expert for nutrient recommendation or retention of residues with a 25% reduction of the RDF had a yield advantage over the present  RDF.
Scientific Model Development for Machinery Safety using Machine Reliability, Integrity and Availability
Authors: Nesan Kartikeyan Patma , Buang Azizul , Kaniapan Sivabalan , Zaini Dzulkarnain
Published: September 2022

Introduction: Machines are equipment that increases productivity and efficiency in a workplace. Machine Reliability, Integrity, and Availability are the most critical factors to ensure machinery safety in a workplace.
Methods: Throughout this study, a series of reviews of previous literature are described in relation to the elements of reliability, integrity and availability. This study examines the methods used to investigate levels of each element as well as the results of performing the analysis. Each review is chosen from the aspect of the safety feature that can be interpreted from the research study. A scientific model that utilizes an improved Bottom-up Approach is proposed to further improve the worker's safety and enhance the productivity of an industry.
Results: Research shows that the chosen reviews have positive and negative change towards the level of machinery safety and a more substantial approach is needed to further strengthen the issue. The proposed model combines the effort of employee and various management organization as a team. The model is validated using Bias- Variance Trade off method that analyses the proposed model in a 27MW power plant with a selection of employee and management.
Conclusion:  Model validation proves that the proposed model is an effective method to increase the machinery reliability, integrity and availability in a workplace. The scientific methodology provided will help management as a team to avert mechanical accidents from occurring at an initial stage.
Impacts of Mercury Exposure on Human Health, Safety and Environment: Literature Review and Bibliometric Analysis (1995 to 2021)
Authors: Palathoti Suvarna Raju , Otitolaiye Victor O. , Mahfud Riyad , Al Rawahi Manar
Published: September 2022

Introduction: Mercury is a highly toxic and persistent contaminant found in food and parts of the environment. Over the years, global research on mercury poison has soared owing to concerns about its effects on human health, occupational safety, and environmental sustainability. Although numerous studies have identified and examined the various types, sources, toxicity, exposure, and impacts of mercury, comprehensive studies on the research landscape and scientific developments on the subject areas are currently lacking. Therefore, this paper shows a bibliometric analysis (BA) and literature review (LR) of the top publications, funders, organisations, and countries working on Mercury research worldwide.
Methods: The research landscape on the subject area was examined by BA from 1995 to 2021, whereas the scientific developments were highlighted through LR.
Results: Results showed that mercury research has gained global prominence since the discovery of the Minamata disease in 1956. The most prolific mercury researchers, institutions, and funders are from the United States, Japan, Brazil, Canada, and China, whereas the publications on Mercury research doubled over the period. The top source titles for publications on Mercury are Neurotoxicology, Science of the Total Environment, and Environmental Health Perspectives. However, Micheal Aschner (US) and Takashi Yorifuji (Japan) are the most prolific researchers. Co-occurrence analysis revealed that mercury, methyl mercury, fish, toxicity, and Minamata disease are the most cited keywords, which shows the correlation nexus between fish consumption and mercury poisoning.
Conclusion: The LR showed that mercury research is widely investigated due to global concerns about its impact on human health, safety, and the environment.
Stress and Depression in the Workplace of Educators in the Philippines
Authors: Orlanda-Ventayen Caren , Ventayen Randy Joy
Published: September 2022

Introduction: Workplace stress and depression should be properly treated to maintain productivity in teaching. Unmanaged stress and depression could lead to severe outcomes that affect the environment in the classroom. Thus, managing stress and preventing depression in the workplace are significant aspects of successful teaching.
Methods: This study aims to determine the level of workplace stress and depression of the educators in the Philippines by gathering their demographic profiles, levels of workplace stress, and the level of depression. A correlation was used if there is a significant difference in the profile between workplace stress and a state of depression. This research study used the descriptive survey method with educators as respondents in the questionnaire during the school year 2019-2020 with a total of 407 respondents.
Results: Based on the study results, teachers disagree that they experience stress in the workplace, and teachers seldom experience depression. The difference shows that the level of stress and depression are lower at vocational and college levels.
Conclusion: Based on the findings, teachers should understand how to practice stress management and prevent depression. School administrators and policymakers should look at possible interventions to minimize the level of stress and depression of educators.
Better Disease Control by Multidrug Regimen in Scabies: A Randomized Controlled Trial
Authors: Pandey Prajwal , Agrawal Sudha
Published: September 2022

Introduction: Scabies is a highly resilient condition with varying morbidity worldwide. The treatment options widely used for the disease include topical permethrin 5% and oral Ivermectin with similar efficacy. Treatment failure due to non-compliance is a major problem with the current treatment modalities.
Objectives: This study was designed to compare the efficacy of combination to the gold standard treatment regimen of scabies.
Materials and Methods: A randomized controlled trial was done with 212 patients, divided randomly into two groups Group 1 and Group 2. Group 1 were treated with two-time application of 5% permethrin one week apart while Group 2 were treated with a combination of 5% permethrin and oral ivermectin (200μg/kg) on a single day. Patients were followed up every week for 4 weeks to assess the efficacy and adverse events.
Results: The treatment efficacy in group 2 was more compared to group 1 after 2 weeks of follow up (72.6% vs 65.1% after 1 week; 89.6% vs 80.2% after 2 week) however it was not statistically significant. After 4 weeks of follow up, the treatment efficacy in both the groups was similar. The reduction in intensity of itching was almost similar in both the groups at every follow up.
Conclusion: The combination of 5% topical permethrin and oral ivermectin showed earlier resolution of clinical symptoms compared to 5% topical permethrin alone repeated in 1 week. The reduction in intensity of itch was similar in both the groups.
Quality of life in Patients with Melasma: A Hospital-Based Study
Authors: Mainali Priyanka , Jha Anil Kumar , Shrestha Shristi , Thapa Deeptara Pathak , Joshi Smita , Amatya Bibush
Published: September 2022

Introduction: Melasma is the most common cause of facial melanosis and one of the most common diseases presenting to the Dermatology department. It can lead to psychological and emotional distress for the patients and can hamper their quality of life. So, this study was done to assess the quality of life among patients with melasma so that the need for couseling of these patients could be assessed along with medical treatment.
Materials and Methods: This was a hospital based cross sectional study with 205 clinically diagnosed cases of melasma during the study period of one year. Melasma area severity index (MASI) score was recorded for each patient. Melasma quality of life was evaluated using the Melasma related Quality of Life (MELASQOL) score. MASI score and MELASQOL score were correlated using the Chi square test and socio-demographic details were also recorded.
Results: The mean MASI score in our study was 14.39 and the mean MELASQOL score was 34.98. The correlation of the MASI score with the MELASQOL score was found to be statistically significant (p value = 0.000).
Conclusion: MELASQOL score can be used to assess the quality of life in patients with melasma and the impairment in quality of life depends upon the MASI score.
Pattern of Dermatological Diseases During the Lockdown and Pre-COVID Period at a Tertiary Care Center in Nepal
Authors: Gyawalee Madhu , Kafle Monique , Amatya Amit , Kayastha Bhaskar Mohan
Published: September 2022

Introduction: Coronavirus disease 19 (COVID-19), which started in China, affected many countries in a short time and spread globally. The Nepal government implemented a strict lockdown to stop the spread of this viral infection.

Objectives: Analyzing the impact of COVID-19-induced lockdowns in the pattern of dermatological diseases in comparison to the non-COVID period of 2019.

Materials and methods: A retrospective cross-sectional study was done by reviewing the data from dermatology out-patients records for four months of each lockdown and four months of the non-COVID period.

Results: There was a 49% and 7% reduction in visits of dermatology outpatients during the first and second lockdown, respectively compared to the pre-COVID period. The number of non-infectious diseases was more compared to infectious diseases. Bacterial infection decreased by 1%. Herpes zoster and scabies increased by 0.5-1% during lockdowns. Cases of eczema and urticaria increased by 2% and 3-5.5% during the first and second lockdowns, respectively. Papular urticaria and sexually transmitted infections decreased by 1% during the second lockdown. Consultations for melasma increased by 1.5%.

Conclusion: There was a reduction in patient visits during both lockdowns. However, a marked reduction was seen during the first lockdown compared to the pre-COVID period.

Pruritic conditions like eczemas, urticarias, and scabies increased, whereas papular urticaria decreased. Pigmentary disorders decreased, but visits for melasma increased. All bacterial infections decreased, whereas herpes zoster increased among viral infections. Chronic diseases like psoriasis and acne vulgaris decreased slightly. The number of sexually transmitted infections (STIs) also decreased. There was no difference in the proportion of infectious and non-infectious diseases compared to the pre-COVID and the lockdown periods.
Aesthetic Dermatology Training During Residency: Do we Need to Revise the Postgraduate Curriculum?
Authors: Marahatta Suchana , Thapa Deeptara Pathak
Published: September 2022

Aesthetic Dermatology (AD) is a growing sub-unit of dermatology. Appearance plays a vital role in enhancing and boosting self-confidence. Reports are showing a growing demand for AD throughout the world. To converge this increasing demand, we must pivot on engendering certified competent dermatologists and hence include this sub-specialty in the dermatology residency program.
Panic buying research: A bibliometric review
Authors: Arafat SM Yasir , Kar Sujita Kumar , Singh Rakesh , Menon Vikas , Sathian Brijesh , Kabir Russell
Published: September 2022

Background: Panic buying has been reported during a period of crisis when people buy an extra amount of essential commodities and hoard them anticipating their future utility. As a newer entity, a bibliometric analysis would reveal the research gaps for further studies. We aimed to do a bibliometric analysis of researches published on panic buying over the past two decades.
Methods: A literature search was conducted in the SCOPUS database using the keyword “panic buying”. All published research in the English language between 1st January 2001 to 1st August 2021 was included in the analysis of this study.
Results: We identified a total of 142 articles on panic buying published over the past two decades. There is an exponential increase in the publication on this topic during the COVID-19 pandemic (n=127). Majority of the articles were published from the United States (n=23), followed by the United Kingdom (n=20), and China (n=20). The Frontiers in Public Health and Journal of Retailing and Consumer Services published the highest number of articles (eight each). Arafat SMY published the highest number of publications as a single author (n=10) and Enam Medical College and Hospital, Bangladesh has the highest number of papers as an institution (n=10). Among all the publishers, Elsevier has published the maximum number of papers (n=38).
Conclusion: There is an exponential growth of panic buying research during 2020-21. The global crisis of the COVID-19 pandemic has been attributed to the recent rise in panic buying research.
Crowdfunding Adoption and Practices in NGOs in India
Authors: Suryavanshi Urvashi
Published: September 2022

NGOs are crucial to the expansion of social cause requirements. There are numerous small NGOs in India working for a range of social concerns that support the uplift of the poor. Funding is the main requirement for an NGO to operate efficiently. In the past, whenever a non-profit organisation (NGO) needed money, they would need to plan fundraising events or approach businesses or wealthy individuals. This approach is effective, but it can eventually become tedious. Some new sources of funding for NGO projects are emerging as investment mechanisms change. In this essay, we talk about how popular it is for NGOs to use crowdfunding as a source of fundraising. With the advancement of the internet and information technology, crowdfunding has seen tremendous growth in recent years. The main goal of this essay is to define crowdfunding and describe its various forms for NGOs in India. Evaluation of the benefits, precautions to be taken, and risk associated with crowd fundraising. Crowd fundraising may be encouraged by India's expanding economy. how well the NGOs are at luring Indian investors.
CONCEPTUAL PRINCIPLES OF THE MANAGEMENT SYSTEM IN HEALTHCARE INSTITUTIONS
Authors: Hurzhiy Polina
Published: September 2022

The article reveals the conceptual principles of management in health care institutions. The purpose of the article is to determine the conceptual foundations of the management system in health care institutions in the context of the state's implementation of the sustainable development strategy. The legal framework that regulates the management process in health care institutions has been defined. Features of medical facilities are outlined. The definition of management in the field of health care has been clarified, taking into account the peculiarities of medical institutions. The subject and object of management in health care institutions are defined. The characteristics of the principles and functions of management are given. The principles on which the management system in health care institutions should be based are the principles of purposefulness; consideration of needs and interests; science; systematicity; interdependence; optimal combination of centralization and decentralization of management; unity; correct selection of personnel; economy The list of functions includes the functions of planning, organization, regulation, coordination, motivation, and control. The content of management methods of medical institutions is covered. Management methods are divided into economic, organizational-administrative and social-psychological. The types of management decisions made in a medical institution for its effective functioning are characterized. Management decisions should be classified according to their focus on the object of management into social, medical, organizational, resource, administrative and economic, management decisions on control. The stages of the management process are described. Four stages of the management process in health care institutions are distinguished: the first is obtaining information about the initial state of the health care institution, its processing and analysis, which allows to assess the current state of the system and make a forecast of the further development of the health care institution; the second is the development and adoption of management decisions; the third is the implementation of a management decision; the fourth is control over the implementation of the management decision. It was determined that management in a medical institution should be based on a systemic approach that will ensure the formation of an optimal management mechanism for the development and effective operation of a health care institution.
Left / abandoned / post-German. Late Gothic Silesian Retables and Their New Settings in the Monastery Church in Mogiła (Cracow), and the Cathedrals in Warsaw and Poznań in the 1940s and 1950s
Authors: Patała Agnieszka
Published: September 2022

Based on three case studies, the text presents the analysis of the process of the reappropriation of three selected “left”/”abandoned”/”post-German” medieval artworks in the three important conservation projects from the first decade of the post-war reconstruction of Poland (1945–1955). The circumstances, course and consequences of mounting late gothic Silesian altarpieces in the presbyteries of the monastery church in Mogiła and in the rebuilt and restored cathedrals in Warsaw and Poznań will be traced. This will enhance the analysis of the process of post-war creation of three monuments of Polish medieval art, different in their architectural and artistic costume and history. They will be examined in the context of foreign artworks, which despite being “left”/”abandoned” remained the carriers of a complicated, multithreaded history, unknown to or ignored by decision-makers.
Relief with Crucifixion Scene in St Martin’s Church in Jawor – the Oldest Silesian Pictorial Epitaph and its Ideological and Artistic Contexts
Authors: Kaczmarek Romuald
Published: September 2022

This paper provides an analysis of the relief block with the Crucifixion scene preserved in the St. Martin’s parish church in Jawor, an important town in the Duchy Jawor-Świdnica in the 14th century. According to the 17th century’s written sources the relief was originally located on the wall of the church’s cemetery mortuary, however the primary written source pertaining to the artwork in question is the inscription running along its three sides. The slab commemorates Johann Sapiens and his family. It is the earliest preserved pictorial epitaph in Silesia and in this part of Europe. Its votive purpose is stated. Moreover, a passage referring to biblical texts as well as formulations, which entered into the consecration rites of churches and altars, provide a premise to interpret this family memorial and epitaph, at the same time, also as an ossuary foundation memorial. These circumstances allow searching for possible models and references in places where the pictorial epitaph found favourable conditions for development already at the dawn of its existence as a type of sepulchral monument. At first sight, Thuringia with Erfurt seem the place geographically closest to Silesia, where stylistically and typologically related artworks have been preserved. However, the crucifix depicted in the relief from Jawor turned out to be rather typical for the contemporary Silesian sculpture too, in contrast to the assisting figures of Virgin Mary and St. John. In consequence, the references and sources of inspiration applied in the process of creation of the assisting figures in relief from Jawor should be searched in western territories of Silesia or having regard to the possibility of drawing inspiration from much older portable microplastic objects as, for example, Byzantine or Romanesque ivory.
РОЛЬ ЕКСТРАКОРПОРАЛЬНИХ МЕТОДІВ ТЕРАПІЇ У ПАЦІЄНТІВ З SARSCOV-2 В КРИТИЧНИХ СТАНАХ
Authors: Гейзе А.В. , Клеузовіч А.О. , Плотніков Г.П. , Рубцов М. С.
Published: September 2022

Мета. Проаналізувати досвід застосування екстракорпоральних методів лікування пацієнтів з SARS-CoV-2. Методи. Проведено 48 екстракорпоральних процедур 27 пацієнтам з лабораторно підтвердженим SARS-CoV-2, двобічною пневмонією та різними супутніми хронічними захворюваннями. Всі пацієнти мали середній бал за шкалою SOFA 8,1 ± 3,1 [мінімум 3, максимум 16] під час надходження до відділення інтенсивної терапії. 19 пацієнтів (70,4%) мали тяжке ушкодження легенів більше 75% за даними комп’ютерної томографії грудної клітини. Показання до початка екстракорпоральної терапії включали цитокіновий шторм, пов’язаний з гострим респіраторним дистрес-синдромом (ГРДС) і септичним шоком. Отримані результати. В цілому кожен пацієнт пройшов як мінімум одну процедуру екстракорпоральної терапії. 11 пацієнтів пройшли від 2 до 6 сеансів. Ізольоване відділення плазми і гемоперфузія дозволили знизити вазопресорну/кардіотонічну підтримку, дещо поліпшити параметри вентиляції, зі значною виразністю, але не тривалим зниженням рівня маркерів запалення. Найбільш раціональним виявилося поєднання методів, що забезпечують швидке видалення агентів, тривалу корекцію гомеостазу і детоксикацію, контрольовану температурну реакцію і гідратацію. Екстракорпоральна терапія не вплинула на обсяг і виразність ушкодження паренхіми легені. 19 (70,4%) пацієнтів, які отримували екстракорпоральну терапію, були переведені з ШВЛ на самостійне дихання, тоді як 8 (29,6%) пацієнтів мали важкі ураження легень понад 75% за даними повторної комп’ютерної томографії грудної клітини. Середня тривалість перебування у відділенні інтенсивної терапії серед тих, що вижили, склала 9 ± 3,5 [хв. 4 макс. 22]. 28-денна летальність і госпітальна летальність склали 25,9% (7). Висновок. Тривала екстракорпоральна терапія у пацієнтів з SARS-Cov-2 продемонструвала ефективність в корекції дисфункцій органів і шокових станів, але не призвела до значного поліпшення виразності тяжкості пошкодженої паренхіми легені.
БЛОКАТОРИ 5-HT3 РЕЦЕПТОРІВ СЕРОТОНІНУ В КОМПЛЕКСІ ІНТЕНСИВНОЇ ТЕРАПІЇ ТРАВМАТИЧНОЇ ХВОРОБИ У ПАЦІЄНТІВ З ПОЛІТРАВМОЮ
Authors: Волкова Ю.В. , Долженко М.О.
Published: September 2022

У рамках дослідження проведено комплексне клініко-лабораторне обстеження пацієнтів з множинною травмою. Ми описали роль рецепторів серотоніну 3-го типу (5-HT3) в патогенезі травматичної хвороби. Виявлено позитивний ефект від застосування блокаторів 5-HT3 в комплексній інтенсивній терапії у пацієнтів з краніо-абдомінальною травмою.
ЗАСТОСУВАННЯ ТІОТРИАЗОЛІНУ В ПОЄДНАННІ З ЕКСТРАКОРПОРАЛЬНОЮ ГЕМОКОРЕКЦІЄЮ У ХВОРИХ З ГОСТРОЮ ІНФЕКЦІЙНОЮ ДЕСТРУКЦІЄЮ ЛЕГЕНЬ У ПІЗНІЙ ПЕРІОД ТРАВМАТИЧНОЇ ХВОРОБИ
Authors: Крутько Є.М.
Published: September 2022

Проведено порівняльний аналіз результатів комплексного обстеження та лікування 28 хворих з важкими формами гострої інфекційної деструкції легень в пізньому періоді (ТХ). 62,5% пацієнтів склали від 20 до 50 років. В основному це були чоловіки – 80,5%. Крім дренування, санації гнійних порожнин і традиційної консервативної терапії, у цих пацієнтів були використані методи екстракорпоральної гемокорекціі для купірування прогресуючого ендотоксикозу. У пацієнтів, які отримували тіотриазолін (в складі передперфузійної підготовки і в складі інтенсивної терапії в постперфузійному періоді), відзначався більш сприятливий перебіг захворювання (швидка позитивна динаміка показників системної запальної відповіді, показників токсемії і кисневого гомеостазу, в порівнянні з пацієнтами, які отримують традиційну терапію), що сприяло скороченню термінів і підвищенню якості лікування пацієнтів. Виявлені зміни вказують на доцільність застосування тіотріазоліну в складі передперфузійної підготовки та базової програми комплексного лікування хворих з гострою інфекційної деструкцією легень в пізньому періоді ТХ.
ВПЛИВ ГОСТРОЇ КРОВОВТРАТИ НА ІОННИЙ БАЛАНС ГОЛОВНОГО МОЗКУ В ПЕРІОПЕРАЦІЙНОМУ ПЕРІОДІ
Authors: Ткачук А.Ю.
Published: September 2022

В клінічних умовах (63 пацієнта з СЖК) вивчали вплив гострої крововтрати на іонний гомеостаз мозку. Встановлено можливі причини церебральної недостатності та порушення свідомості у пацієнтів даної категорії.
Modern trends in the development of the fruit and berry sector of the agro-industrial complex of the Orel region
Authors:   VNIISPK, Orel, Russia, Karpova Olga I. , Knyazev Sergey D. ,   VNIISPK, Orel, Russia
Published: September 2022

The article analyzes the dynamics of the level of self-sufficiency in fruits and berries in Russia, as well as Russian imports of fruit and berry products. The place of Orel region between regions of Central Federal District, including dynamic of fruit and berry plantations, gross collection of horticultural production, productivity of fruit and berry crops for last five years, is determined. A comparative assessment of local self-sufficiency of population of the region with fruits and berries with fruit consumption standards in Russia is given. Key problems of development of the fruit and berry sector of agricultural economy in the Orel region were identified. As a solution to the problem, related with the system of promotion and marketing, which does not function effectively enough, the authors proposed formation and development of a cooperative mechanism with the participation of the Center for Agricultural Advice of the Orel Region and the Orel Regional Export Support Center with financial support under existing regional program for the development of agriculture and regulation of agricultural raw materials and food markets until 2025.
A influência do ácido salicílico no desenvolvimento inicial do trigo
Authors: Camargo Anderson , Patricia Freitas Carla , Maders Letícia Rocha , Soster Maria Tereza Bolson
Published: September 2022

O ácido salicílico (AS) possui a capacidade de regular o crescimento e o desenvolvimento das plantas. Desse modo, o objetivo desse estudo foi avaliar a influência do AS no processo germinativo de sementes e no desenvolvimento inicial de plântulas (aérea e radicular) em diferentes cultivares de trigo. O delineamento experimental foi inteiramente casualizado em esquema fatorial 5x2, ou seja, 5 cultivares de trigo, sendo elas: TBIO Energia, TBIO Pioneiro, TBIO Sinuelo, TBIO Noble, TBIO Audaz e uma dose de ácido salicílico 400 mg/L como tratamento e o controle, utilizando somente agua, com quatro repetições, totalizando 40 parcelas. As parcelas foram compostas por 50 sementes de cada cultivar, totalizando 250 sementes por tratamento. Foram mensurados o poder germinativo das sementes, comprimento médio da parte aérea e da raiz. Os resultados mostraram que a embebição das sementes com AS na concentração de 400 mg/L não influenciou, significativamente, no poder germinativo das cultivares de trigo, mas aumentou o comprimento da parte aérea em 1,15 cm. Apesar disso, influenciou, negativamente, no comprimento radicular, com diferença de 5,06 quando comparado ao tratamento com água. Portanto, a concentração de 400 mg/L do AS não é recomendado no desenvolvimento da plântula de trigo. Com isso, há a necessidade de mais estudos utilizando diferentes concentrações de AS para obter uma melhor dose-resposta
Avaliação do desempenho e rendimento de carcaça de diferentes grupos genéticos de bovinos de corte suplementados com ração no cocho
Authors: Barp Murilo José , Patricia Freitas Carla , Camargo Anderson Camargo , Teixeira Amito José
Published: September 2022

A suplementação, no cocho, para bovinos de corte, é utilizada na cadeia produtiva, pois essa prática acelera a terminação e antecipa a idade ao abate. O objetivo desse estudo foi avaliar o ganho médio diário (kg/animal), peso final, peso de carcaça quente e rendimento de carcaça (kg) de diferentes grupos genéticos de bovinos de corte com suplementação no cocho. Os dados foram submetidos à análise de variância e às médias comparadas por meio do teste de Tukey, com nível de significância de 5%. Os resultados mostraram que a raça Angus teve maior média de ganho diário (0,880 Kg) entre os diferentes grupos de raças, seguido da raça Braford (0,782 Kg) e mestiços (0,578 Kg). A variável peso final, não diferiu, significativamente, entre mestiços (368 Kg) e Angus (378 Kg), assim como foi menor para Braford (352 Kg). Em relação ao peso de carcaça quente a raça Angus (191 Kg) foi, significativamente, superior aos mestiços (181Kg) e Braford (174Kg), os quais não diferiram entre si. Para rendimento de carcaça não houve diferença significativa entre as diferentes raças. Esse estudo pode contribuir mostrando que o uso da suplementação no cocho permite melhorar o desempenho de diferentes grupos genéticos de bovinos de corte
Argilas modificadas para adsorção do corante Rodamina B
Authors: Parodia Anderson , Schwanke Anderson Joel , Rigoti Eduardo , Prasniski Janaina Arlete , Pergher Sibele
Published: September 2022

Uma argila bentonita natural (Bofe) proveniente de um depósito localizado em Boa Vista (PB-Brasil) foi submetida a dois processos de intercalação diferentes, tais como organofuncionalização, usando cátions de hexadeciltrimetilamônio em diferentes concentrações e pilarização, usando o íon de keggin de alumínio. As amostras foram caracterizadas por difração de raios X e aplicadas a testes de adsorção do corante orgânico Rodamina B. Os testes foram realizados empregando 0,5 g da argila modificada em 100 mL de uma solução de 50 ppm de Rodanima B. Alíquotas de 1 mL foram retiradas nos tempos de 0 a 8 h, 24 h e 72h e analisadas por espectroscopia de UV-Vis. A amostra que apresentou o melhor resultado foi a Org 5/2, que alcançou, aproximadamente, 97% de remoção
Caracterização físico-química de folhas e atividade antioxidante de extratos de Pereskia aculeata Mill. obtidos por ultrassom
Authors: Fernandes Ilizandra , Zanoello Paloma , Nascimento Lucas Henrique , Fonseca Duarte Patrícia , Saorin Puton Bruna Maria , Schenatto Palavicini Sandra  Maria , Colet Rosicler , Paroul Natalia , Cansian Rogério Luis
Published: September 2022

Pereskia aculeata Mill., popularmente conhecida como ora-pro-nobis e “carne-de-pobre”, devido ao teor de proteína das folhas, é considerada planta alimentícia não-convencional (PANC). O trabalho teve como objetivo a caracterização físico-química das folhas de P. aculeata e a avaliação da atividade antioxidante e conteúdo de compostos fenólicos em seu extrato. As folhas foram liofilizadas e realizada a caracterização físico-química determinando umidade, proteínas, cinzas, lipídeos e minerais. Para avaliação do potencial antioxidante e dos compostos fenólicos totais foi realizada a extração assistida por ultrassom durante 1 hora a 40, 60 e 80ºC, em água. Nas folhas de P. aculeata foram encontradas quantidades significativas de proteínas (18,56%) e minerais (15,17%), principalmente cálcio (8.012,83 mg/100g) e potássio (10.693,80 mg/100g) e baixas concentrações de lipídeos (4,28%) e umidade (1,32%).  A extração de 1 hora em ultrassom (40 kHz, 132 W) a 60ºC, foi suficiente para obter extratos com potencial antioxidante (0,291 mg/mL) e alta concentração de compostos fenólicos totais (4,209 mgEAG/100g). Os resultados referentes ao teor de proteína e compostos com propriedades antioxidantes indicam a utilização das folhas de P. aculeata, tanto para a alimentação in natura, como para uso de seus extratos em formulações de alimentos industrializados para aumento de seu valor nutricional
Extração de sementes de Eugenia involucrata DC com diferentes métodos e solventes
Authors: Saorin Puton Bruna Maria , Lisboa Bernardi Julia , Thomazoni Laís , Mazetto Guilherme Henrique , Smaniotto Jaqueline , Fernandes Ilizandra Aparecida , Dallago Rogério Marcos , Paroul Natalia , Cansian Rogério Luis
Published: September 2022

O objetivo do trabalho foi avaliar a atividade antioxidante, o teor de compostos fenólicos e flavonoides e a atividade antibacteriana de diferentes extratos de semente de Eugenia involucrata obtidos por extrações sucessivas em Soxhlet e por maceração, utilizando os solventes hexano e álcool etílico. A atividade antioxidante foi fundamentada na medida da absorção do radical 2,2-difenil-1-picril hidrazil (DPPH•) em 515 nm. O teor de compostos fenólicos totais foi avaliado pelo método de Folin Ciocalteu e, os flavonoides, pelo método com nitrato de alumínio e acetato de potássio. A concentração inibitória mínima (CIM) foi determinada pelo método de microdiluição seriada em meio de cultura. A atividade antioxidante foi maior para os extratos obtidos com álcool etílico, sendo de 0,1390 mg/mL para o extrato macerado e 0,1704 mg/mL para o obtido por soxhlet. Em relação aos compostos fenólicos e flavonoides, o extrato etanólico, obtido por soxhlet, apresentou maior valor, 41,18 mg.EAG/g e 2,76 mg.EQ/g, respectivamente. Quanto à faixa de inibição da CIM, os valores situaram-se entre 25 a 200 mg/mL. A extração das sementes de E. involucrata com a utilização de solventes polares pode gerar extratos com potencial antioxidantes, que podem ser utilizados pela indústria de alimentos e de cosméticos
CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF NEUROLOGICAL VARIANTS OF POST-COVID SYNDROME ON THE EXAMPLE OF THE NEUROLOGICAL CLINIC OF THE STATE NOVOSIBIRSK REGIONAL CLINICAL HOSPITAL
Authors:   Novosibirsk State Medical University, Polyanskaya V.V. , Arkhipov I.E. ,   Novosibirsk State Medical University; State Novosibirsk Regional Clinical Hospital, Taneeva E.V. ,   State Novosibirsk Regional Clinical Hospital, Veretelnikov I.A. ,   State Novosibirsk Regional Clinical Hospital, Shchepankevich L.A. ,   Novosibirsk State Medical University; State Novosibirsk Regional Clinical Hospital
Published: September 2022

Introduction. On March 11, 2020, WHO declared a pandemic of a new coronavirus infection. In addition to the pandemic's high mortality worldwide, its deferred effects are receiving increasing attention. With the accumulation of research data, it became obvious that a new coronavirus infection is capable of inducing both direct and indirect effects on the nervous system. Aim. The study of the clinical and epidemiological characteristics of neurological variants of post-covid syndrome using the example of the neurological clinic of the State Budgetary Healthcare Institution Novosibirsk Regional Clinical Hospital for the period from July 2020 to February 2022. Materials and methods. A retrospective analysis of 1 500 case histories of patients with a past history of COVID-19 admitted with a manifestation of various neurological diseases for the period from July 2020 to January 2022. In addition to the manifestation of neurological diseases , we took into consideration gender, age, concomitant diseases, and duration of a new coronavirus infection. Results. Of the analyzed case histories with laboratory-confirmed COVID-19 and overt neurological conditions, 30 people were identified. Concomitant neurological disorders with a predominant lesion of the peripheral nervous system accounted for 23% (according to the type of Guillain-Barré syndrome — 16%, the remaining 7% had symptoms of chronic demyelinating polyneuropathy), the central nervous system — 74% (isolated cases of meningoencephalitis, autoimmune encephalomyelitis, ischemic stroke; up to 60% of encephalopathies of various origins), 3% accounted for musculoskeletal pathology, represented by idiopathic myodystrophy. Conclusion. Thus, no significant differences were found between the results obtained and the data of foreign and domestic colleagues. The precise data on frequency of neurological variants of post-COVID syndrome are currently unknown, however, there is a tendency that patients who have had a severe form of COVID-19 are more prone to the development of neurological complications after infection in the period up to 6 months.
SCREENING PATHOANATOMICAL EXAMINATION OF THE PLACENTA AS A RESERVE FOR REDUCING PERINATAL MORTALITY
Authors:   Novosibirsk State Medical University, Nadeev A.P. ,   City Clinical Hospital No. 1, Karpov M.A. ,   Novosibirsk State Medical University; City Clinical Hospital No. 1, Nizovtsev K.A. ,   Novosibirsk State Medical University
Published: September 2022

Introduction. The continuity of the morphofunctional system "mother-placenta-fetus" allows for the histological examination of the placenta to reveal risk groups for the newborn, pregnant women, puerperas, and to take out preventive measures. Aim of the research. To study the structure and localization of pathological changes in the placenta and the significance of mass pathomorphological studies as a reserve for reducing infant and perinatal mortality. Materials and methods. The afterbirths were examined according to the algorithm proposed by A.P. Milovanov (1999). Histological examination assessed the maturity of the placenta, the severity of compensatory-adaptive reactions and involutive-dystrophic changes, noted the presence and severity of inflammatory changes both in the placenta (placentitis, intervillusitis, villusitis) and extraplacental membranes (choriodeciduiitis, chorioamnionitis). Results. In a large-scale pathoanatomical examination of placentas, the proportion of normal mature placentas without pathological findings was up to 20%. The main pathological process in the placenta is an acute and chronic inflammation, often combined with chronic placental insufficiency (up to 77%). Among the forms of chronic placental insufficiency, the variant of pathological immaturity predominates – immature intermediate villi. For severe inflammation, the most common localization was noted in the fetal membranes, which reflects the ascending route of intrauterine infection. For chronic inflammation, the most common localization was basal deciduitis and parietal choriodeciduitis, which is associated with a high incidence of latent infectious foci in women. Conclusion. A large-scale pathoanatomical examination of placentas , with the identification of risk groups for newborns, along with other factors, can serve as a reserve for reducing perinatal and early neonatal mortality.
Predictive Value of Swede Colposcopy Score for Predicting Cervical Intra Epithelial Neoplasia in Cervical Cancer Screening with Visual Inspection with Acetic Acid
Authors: Bidhuri Shubham , Shamsunder Saritha , K Harshitha , Malik Sunita , Gautam Akriti , Pangtey Priyanka , Arora Rashmi , Ahluwalia Charanjeet
Published: September 2022

Objectives: To assess the predictive value of Swede score with VIA as the screening method and identify a cut-off score that predicts high grade CIN. Methods: Records of 324 women who were VIA positive and had acetowhite lesion on colposcopy graded according to Swede score followed by biopsy/excisional procedure were included in the analysis. Sensitivity, Specificity, PPV & NPV for each Swede score were calculated and area under the ROC curve (AUROC) for score predicting high grade histopathology (≥ CIN 2) was estimated. A p value less than 0.05 was considered statistically significant. Results: As the swede score increased from 0 to 10, the sensitivity decreased and specificity increased i.e. sensitivity of score < 6 was high whereas specificity of score > 6 was high. At a cut-off of Swede Score ≥6, it predicted high grade histology with a sensitivity of 51%, and a speci-ficity of 79%. The highest diagnostic accuracy was at swede score cut off >6 i.e. 64.6%. Conclusion: We recommend biopsy at a Swede score of 5 or less and treatment by excision at a Swede score of 6 or more.
Characteristics of Chronic Lymphocytic Leukemia in Sudanese Patients
Authors: Basabaeen Ameen Abdulaziz , Abdelgader Enaam Abdelrhman , Babekir Ebtihal Ahmed , Abdelateif Nour Mahmoud , Osman Abdelrahim Sadia , Altayeb Osama Ali , Fadul Eman Abbass , Osman Hussam Ali , Bamusa Salem Ahmed , Khider Ibrahim Ibrahim
Published: September 2022

Objective: Our study aimed to characterize clinical, hematological and Immunophenotyping patterns in Sudanese patients with Chronic Lymphocytic Leukemia. Methods: A cross-sectional study was conducted in Khartoum state, Sudan, during the period from April 2017 to April 2018, involved 110 CLL patients. Physical examination, Complete Blood Count and Immunophenotyping were performed for all patients to confirm the diagnosis. Clinical staging such as Rai and Binet stages were applied. The statistical analysis was performed by using SPSS version 23.0. Results: In this study, 71.8% were males and 28.2% were females. Lymphadenopathy, splenomegaly, hepatomegaly, leukocytosis, thrombocytopenia, and anemia were seen in 71%, 49%, 13%, 60.9%, 39% and 34.5% of patients respectively. However, about 90% of patients displayed an advanced Rai risk stage and 70% were at Binet stage B or C. All CLL samples expressed CD45, CD19 and CD20. All the CLL cases were negative for the T-cell marker CD3.CD5 was expressed in 80% patients; CD23 was expressed in 92.7% patients. CD22, CD79b and FMC7 were negative in 91.8%, 77.3%, and 96.4% of patients respectively. Conclusions: CLL in Sudan is a disease of the elderly and more frequently in males than females. The incidence at young patients was higher than those reported by Western studies. Most of our patients presented advanced Rai and Binet stages. CD22 may be a highly specific marker for diagnosing CLL in Sudanese patients and should be included in all diagnostic panels used to differentiate CLL from other B cell lymphoproliferative disorders in Sudan.
Accuracy of ultrasound guided fine needle aspiration cytology in head and neck lesions
Authors: Mohson Khaleel , Ali Jafaar Mohammed
Published: September 2022

Background:  Palpable superficial mass (es) is a major complain making patients attending any surgical and otolarygeal clinic. Most of these lesions are related to thyroid, cervical lymph nodes or salivary glands Triple assessment technique using clinical examination, ultrasound and cytology are usually sufficient in reaching the final diagnosis especially in specialized surgical centers. Aims: The objective of this study was to assess how accurate ultrasound in guessing the diagnosis of the lesion and how accurate as a guide for fine needle aspiration cytology (FNAC). Methods: A prospective study included 50 patients who were presented with self-detected head or neck lump and attending the specialized surgical clinic in the Medical City Complex, Baghdad during the period from November 2019 to October 2020. Their age ranged from 10-63 years. Patients were underwent ultrasound examination after clinical examination and then subjected to ultrasound guided FNAC. Results: Twenty patients presented with palpable lump were included in this study. Their ages ranged between 10 to 63 years (mean age 37.8 years). Regarding the distribution of the anatomical locations the majority of the lesions were lymph nodes (7/20) six of them are cervical and one of them was inguinal, the 2nd common location was the parotid gland seen in four out of twenty, The provisional diagnosis provided by ultrasound for lococregional pathology was benign in majority of Lymph node group (5/7) and malignant in two, three out of four parotid lesions are benign and all thyroid cases are also benign, The FNAC results in correlation with ultrasound findings are in concordance regarding the lymph nodes and parotid aspirates in 100% while thyroid aspirate was in concordance in 100% after two passes due to bloody aspirate, the aspirate from the breast is 50% in line and no concordance seen in 50 %, the aspirate is compatible regarding the hip mediastinum and sternomastoid while is not conclusive in lung aspirate. The accuracy of ultrasound in guiding the needle for targeting the lesion is 100%, and overall accuracy of ultrasound in reaching the final diagnosis is 85% with 100 % sensitivity. Conclusion: Ultrasound guided FNAC represents a reliable interventional radiology modality for targeting the needle to any superficial or ultrasound reachable deep seated head and neck lesion and considered a recommended method for assessment of underlying cause responsible for palpable head and neck mass this is due to reliable focusing the mass lesion, avoiding nearby vital organ or vessel and direct real time visualization of the needle within the lesion and by that sampling cells by flickering the needle within the lesion.
Indications, Surgical Techniques and Results of Breast Oncoplasty in West Africa, Case of Burkina Faso
Authors: Zongo Nayi , Yameogo Parateyandé Bonaventure , Nare Amélie , Djigemdé Adeline R , Halim Bagué Abdoul , Ouedraogo Nomwendé Lamoussa Marie , Windsouri Mamadou , Dem Ahmadou
Published: September 2022

Objective: To describe the indications, surgical techniques and results of breast oncoplasty. Patients and methods: Retrospective and descriptive study of oncoplastic breast surgery performed between January 2013 and March 2021. We were interested in the indications, techniques, and aesthetic and oncological results. Overall survival was assessed by the Kaplan Meier technique and survival comparisons by logRank. Aesthetic results and quality of life were assessed by the modified BREAST-Q questionnaire. Results: We report 64 cases of oncoplastic breast surgery in Ouagadougou, that is 6.9% of the 917 surgeries performed for breast cancers. We performed 14 Round Block for upper quadrant carcinomas. Eight external oncoplasties were performed for infiltrating ductal carcinomas of the external quadrants. The upper pedicle technique was performed in 19 cases and the Thorek amputation graft technique in 13 cases for lower quadrant carcinomas with macromastia and major ptosis. The supero-postero-internal pedicle technique help to avoid necrosis and amputation of the nipple in 8 cases. The 5-year overall survival was 90.5%. The patients were satisfied with the volume of the remaining breasts and their aesthetic appearance. Conclusion: Oncoplasty is increasingly performed in Burkina Faso. It should take its place with the recent advent of radiotherapy in our country. A larger cohort will better describe its results.