bluuebunny/crossref_metadata_2025 huggingface dataset:
Les usages de Twitter au Festival de Cannes. Pratiques numériques et construction des opinions esthétiques
Authors: Dougados Myriam , Fabiani Jean-Louis , Gaillard Julien
Published: July 2018

Este artículo es una contribución al análisis de los efectos de las redes sociales sobre la formación de los gustos y de las opiniones en materia cultural. Tomando el ejemplo de los usos de Twitter en el festival de Cannes de treinta y dos profesionales (socios de Vodkaster) que tocan juntos en la escena local, y apoyados fundamentalmente en un análisis lexical, podemos dar a luz tres nociones estructurantes : la de outsider numérico (la desviación constitutiva del acontecimiento), la de liderazgo fundada sobre la fidelidad de los lectores y la del cuarto círculo de espectadores que construye su experiencia del festival en su nombre. Las redes sociales constituyen a la vez un recurso fácilmente explotable para el análisis de los públicos y una forma específica de la sociabilidad del festival.
La directive européenne sur la sécurité des opérations pétrolières et gazières en mer
Authors: Juste Ruiz José
Published: July 2018

Suite à l’accident de la plateforme de forage Deepwater Horizon dans le Golfe du Mexique en 2010, l’Union Européenne adopta la directive 2013/ 30/ UE du 12 juin 2013 relative à la sécurité des opérations pétrolières et gazières en mer et modifiant la directive 2004/ 35/ CE. L’objet essentiel de la directive est de prévenir les accidents majeurs et limiter leurs conséquences en établissant des exigences minimales de sécurité pouvant contribuer indirectement à améliorer les conditions environnementales et de santé des travailleurs lors des opérations pétrolières et gazières en mer. La directive modifie aussi la directive 2004/ 35/ CE du 21 avril 2004 sur la responsabilité environnementale pour la rendre applicable en mer. Dans l’ensemble, la directive 2013/ 30/ UE constitue un pas en avant en matière de sécurité des opérations pétrolières et gazières en mer. Mais les règles établies ne sont ni claires ni complètes ; elles ne contiennent que des obligations déclinées en termes de droit mou (soft law) qui ne s’appliquent pas aux accidents majeurs pouvant se produire en haute mer dans les diverses régions marines de l’Union ou dans les eaux hors de l’Union.
Bouleversement climatique : penser ce qui vient avec Bruno Latour
Authors: Gutwirth Serge
Published: July 2018

The disruption of the climate : thinking what is coming with Bruno Latour. In his contribution Serge Gutwirth presents Bruno Latour’s article by describing the issue of climate disruption and the geopolitical and philosophical debates it raises.
L’ascension et la chute de l’utilisation de l’énergie nucléaire en Allemagne : les processus, les explications et le rôle du droit
Authors: Winter Gerd
Published: July 2018

The rise and fall of nuclear energy in Germany. Processes, Explanations and the Role of Law. After the disaster of Fukushima in March 2011, some countries, especially Germany, dramatically changed their energy policy in order to end the use of nuclear fission in the energy production. The article retraces the historical and legal background of Germany nuclear policies. Firstly, it lists the different phases in the use of nuclear energy. Then, it tries to find an explanation for why the nuclear exit occurred. Thirdly, it analyses the role of regulatory and constitutional law in the introduction and phasing out of nuclear energy use. Finally, general conclusions are drawn on the advantages and drawbacks of nuclear energy, and also on lessons to be learned for socio-legal theory.
An Imaging Algorithm for a Lunar Orbit Interferometer Array
Authors: Huang Qizhi , Sun Shijie , Zuo Shifan , Wu Fengquan , Xu Yidong , Yue Bin , Ansari Reza , Chen Xuelei
Published: July 2018

Radio astronomical observations below 30 MHz are hampered by the refraction and absorption of the ionosphere as well as the radio frequency interference (RFI), and thus, high angular resolution sky intensity map is not yet available. An interferometer array on lunar orbit provides a perfect observatory in this frequency band: it is out of the ionosphere, and the Moon helps to block the RFIs from the Earth. The satellites can make observations on the far side of the Moon and then send back the data on the near-side part of the orbit. However, for such arrays, the traditional imaging algorithm is not applicable: the field of view is very wide (almost whole-sky), and for baselines distributed on a plane, there is a mirror symmetry between the two sides of the plane. A further complication is that for each baseline, the Moon blocks part of the sky, but as the satellites orbit the Moon, both the direction of the baseline and the blocked sky change, so even imaging algorithms that can deal with a noncoplanar baseline may not work in this case. Here, we present an imaging algorithm based on solving the linear mapping equations relating the sky intensity to the visibilities. We show that the mirror symmetry can be broken by the three-dimensional baseline distribution generated naturally by the precession of the orbital plane of the satellites. The algorithm is applicable and good maps can be reconstructed, even though the sky blocking by the Moon is different for each baseline. We also investigate how the map-making is affected by inhomogeneous baseline distributions.
Testing the Weak Equivalence Principle Using Optical and Near-infrared Crab Pulses
Authors: Leung Calvin , Hu Beili , Harris Sophia , Brown Amy , Gallicchio Jason , Nguyen Hien
Published: July 2018

The Weak Equivalence Principle states that the geodesics of a test particle in a gravitational field are independent of the particle’s constitution. To constrain violations of the Weak Equivalence Principle, we use the one-meter telescope at Table Mountain Observatory near Los Angeles to monitor the relative arrival times of pulses from the Crab Pulsar in the optical (λ ≈ 585 nm) and near-infrared (λ ≈ 814 nm) using an instrument that detects single photons with nanosecond-timing resolution in those two bands. The infrared pulse arrives slightly before the visible pulse. Our three analysis methods give delays with statistical errors of Δt
obs = 7.41 ± 0.58, 0.4 ± 3.6, and 7.35 ± 4.48 microseconds (at most 1/4000 of the pulsar period). We attribute this discrepancy to systematic error from the fact that the visible and infrared pulses have slightly different shapes. Whether this delay emerges from the pulsar, is caused by passing through wavelength-dependent media, or is caused by a violation of the equivalence principle, unless there is a fine-tuned cancellation among these, we set the first upper limit on the differential post-Newtonian parameter at these wavelengths of Δγ < 1.07 × 10−10 (3σ). This result falls in an unexplored region of parameter space and complements existing limits on equivalence-principle violation from fast radio bursts, gamma-ray bursts, as well as previous limits from the Crab.
Anti-Human Herpesvirus 8 antibodies affect both insulin and glucose uptake by virus-infected human endothelial cells
Authors: Angius Fabrizio , Piras Enrica , Spolitu Stefano , Marras Luisa , Armas Sara Federica , Ingianni Angela , Contini Pierpaolo , Pompei Raffaello
Published: July 2018

Introduction: Human Herpesvirus 8 (HHV8) is known to be the cause of the malignant tumour named Kaposi’s sarcoma. It is believed to induce an intense modification of cell metabolism in endothelial cells. In this work we analysed the role of anti-HHV8 antibodies in both the insulin and glucose uptake of HHV8-infected primary human endothelial cells (HUVEC).

Methodology: Western blotting, immunofluorescence and radiolabelled glucose were employed to assess the pPI3K expression, insulin binding and glucose-uptake by HUVEC cells, respectively.

Results: We confirmed that HHV8-infection is able to enhance both insulin binding and glucose-uptake in HHV8-infected primary endothelial cells; in addition, we found that anti-HHV8 specific antibodies are able to further increase both insulin and glucose uptake during the late latent phase of HHV8-infection in vitro.

Conclusions: These findings suggest that a specific immune response to HHV8-infection may cooperate in boosting the cell metabolism, further enhancing the already increased insulin binding and glucose-uptake in HHV8-infected cells, which is a peculiar property of several oncogenic viruses.
Comparison of serum level of 25(OH) vitamin D3 in brucellosis patients with healthy persons in Hamadan, west of Iran
Authors: Keramat Fariba , Alikhani Mohammad Yousef , Poorolajal Jalal , Akbari Surur
Published: July 2018

Introduction: The human immune system including phagocytosis, has anessential role in pathogenesis, relapse and improvement of infectious diseases. The immune cells have vitamin D receptor, and vitamin D deficiency causes impaired immune system, specifically macrophages. The aim of study was to compare serum levelof 25-hydroxyvitamin D3 (25-OH- VitD3) among the patients with acute brucellosis and relapsed brucellosis with healthy individuals.

Methodology: In this case-control study, 92 patients with acute brucellosis, 92 cases with relapsed brucellosis and 107 healthy persons who referred to Sina hospital and Imam Khomeini clinic were enrolled, and all groups were matched based on age, gender and habitat. The study was done from March 2016 to June 2017. The serum levels of 25-OH- VitD3 were measured based on the Enzyme Linked Fluorescent Assay (ELFA) technology, Vidassystem (France, Biomerieux Kit). The data were analyzed by using SPSS version 16 software.

Results: The mean serum levels of 25-OH- VitD3 in acute brucellosis, relapsed brucellosis and healthy persons were 22.55 ± 15.72, 26.82 ± 20.78, 24.44 ± 17.29, respectively .In addition, the mean serum levels of 25-OH- VitD3 by male gender in acute brucellosis, relapsed brucellosis and healthy control groups were 20.35 ± 13.10, 24.88 ± 20.89 and 22.52 ± 13.79, respectively. However, there was no statistically significant difference among three groups (P = 0.275).

Conclusions: According to the results, the prevalence of vitamin D deficiency was high in patients with acute or relapsed brucellosis and also healthy persons; however, there was no meaningful difference among three groups and between the patients and healthy persons.
Large-scale hepatitis C combating campaigns in Egypt and Georgia; past, current and future challenges
Authors: Amer Fatma Abdelaziz
Published: July 2018

Hepatitis C virus (HCV) infection is a major worldwide problem which should be adequately combated. This review summarizes two successful model programs to eradicate Hepatitis C in two countries; Egypt and Georgia. Egypt tops the list of nations affected by HCV, and Georgia is ranked among other countries with huge HCV burden. Currently, both countries are on their ambitious way to making history and completely eliminate Hepatitis C virus infections.

The first comprehensive approach to reduce the burden of hepatitis C and associated diseases in Egypt was achievable with the formulation of the National Committee for Control of Viral Hepatitis (NCCVH) in 2006. Assisted by international and national stalk holders, Georgia started its nation- wide HCV fighting program in 2015. Elements of programs mostly addressed in both countries included simplifying and improving access to the package of diagnosis and care- providing effective, affordable or free of charge treatment- issuing, applying and regularly updating practice guidelines- improving surveillance, monitoring, and research focusing specifically on the risky groups- emphasizing infection control (IC) - encouraging patient and community engagement and increasing public and political commitment. Interventions are still going on to eradicate HCV infection in Egypt by 2030 and in Georgia by 2020. Lessons gained from this program can educate comparable activities in different nations and help control the worldwide epidemic of viral hepatitis.
BBI: an R package for the computation of Benthic Biotic Indices from composition data
Authors: Cordier Tristan , Pawlowski Jan
Published: July 2018

The monitoring of impacts of anthropic activities in marine environments, such as aquaculture, oil-drilling platforms or deep-sea mining, relies on Benthic Biotic Indices (BBI). Several indices have been formalised to reduce the multivariate composition data into a single continuous value that is ascribed to a discrete ecological quality status. Such composition data is traditionally obtained from macrofaunal inventories, which is time-consuming and expertise-demanding. Important efforts are ongoing towards using High-Throughput Sequencing of environmental DNA (eDNA metabarcoding) to replace or complement morpho-taxonomic surveys for routine biomonitoring. The computation of BBI from such composition data is usually being undertaken by practitioners with excel spreadsheets or through custom script. Hence, the updating of reference morpho-taxonomic tables and cross studies comparison could be hampered. Here we introduce the R package BBI for the computation of BBI from composition data, either obtained from traditional morpho-taxonomic inventories or from metabarcoding data. Its aim is to provide an open-source, transparent and centralised method to compute BBI for routine biomonitoring.
Giant Occipitocervical Encephalocele
Authors: Chaturvedi Jitender , Goyal Nishant , Arora Rajnish Kumar , Govil Nishith
Published: July 2018

Encephaloceles are cranial defects in which sac contains herniating brain, which is often gliotic. Congenitally, this defect may extend into posterior elements of cervical vertebrae and leads to occipitocervical encephalocele. When the size of this sac is larger than head size, they are termed as giant. Very young age and associated congenital anomalies in these patients pose significant challenges in diagnostic, anesthetic, and surgical techniques. We share a case of giant occipitocervical encephalocele managed at our institute and discuss about its management issues with review of literature.
Guillain–Barre Syndrome: A Rare Presentation of Borderline Tuberculoid Leprosy with Type 1 Lepra Reaction
Authors: Dash Deepa , Saluja Alvee , Singh Rajesh Kumar , Bhatia Rohit , Tripathi Manjari
Published: July 2018

Guillain–Barre syndrome (GBS) is an autoimmune polyradiculoneuropathy usually preceded by respiratory tract or gastrointestinal infection. The pathogenesis in GBS is based on molecular mimicry mechanism. Hansen's disease is common in India and is the most common infectious cause of neuropathy. We describe a 42-year-old man who was being treated for borderline tuberculoid leprosy and developed Type 1 lepra reaction followed by GBS and responded to plasmapheresis. Lepra reaction may lead to exposure of neural antigens, resulting in autoimmune mechanism and demyelination of peripheral nerves.
The Role of Brain Magnetic Resonance Imaging (MRI) as an Early Detector of Cognitive Impairment
Authors: Yueniwati Yuyun , Wangsadjaja Charles , Yulidani Islana Gadis , Rianawati Sri Budhi , Al Rasyid Harun
Published: July 2018

Background: Along with the increase of the health and prosperity level will affect the life expectancy in Indonesia, there has also been an increase in degenerative disease cases. One of the problems arises is cognitive impairment. The mild version of this impairment is often associated with the increase risk that will eventually lead to dementia. Therefore, early detection of this impairment is necessary. Objective: This study is aimed at proving the correlation between Fazekas scale on brain MRI and MoCA-Ina score in defining the degree of cognitive impairment. Methods: This study employed observational analytic design and cross sectional study for its data collection method. The Fazekas scale on brain MRI of 32 patients was read by 3 radiologist, while the MoCA-Ina scoring was done by a competent neurologist. Both tests were done double blindly. Later on, the correlation between Fazekas scale and MoCA-Ina score would be assessed using Spearman Correlation. Results: Statistical calculation conducted using Spearman Correlation reveals that the coefficient is -0.519 with significant score (P) 0.002, which is smaller than α: 0.05. Therefore, it can be concluded that there is a strong negative correlation between Fazekas scale and MoCA-Ina score. Conclusion: Fazekas scale evaluation on brain MRI is necessary to be performed as it helps predicting the decline of one's cognitive function, so that an early therapy can be acted upon to prevent dementia in the future.
Water quality of springs in areas under different land uses in the southern highlands of Santa Catarina
Authors: Ramos Saulo Tadeu Branco , Mafra Maria Sueli Heberle , Rech Tássio Dresch , Siegloch Ana Emília , Rech Ângela Fonseca
Published: July 2018

This study sought to characterize the conditions of springs used for domestic consumption and to analyze their water quality. The springs are situated in catchment areas (drainage areas) with different soil uses in rural properties of the southern plateau of Santa Catarina, Brazil. To this end, 56 springs used to supply rural properties were selected in the counties of Lages, Otacílio Costa, São José do Cerrito, Painel, and Bocaina do Sul. The water catchment area of the springs were described in detail with regard to topography, management, forest, protection, fences, channels to contain runoff, and macroscopic aspects of water. In addition, the water was analyzed for total and fecal coliforms, pH, dissolved oxygen, electrical conductivity, temperature, clarity, and nitrate and total phenol contents. The samplings for water analysis were performed in compliance with Standard Methods for Examination of Water and Wastewater (APHA). The above parameters were evaluated under the following soil uses in the drainage areas: native forest, native grassland, planted pine forest, and cropland. Data were analyzed by comparison of means by the Student's t test (p <0.05). More than 80% of the springs were found to be contaminated with fecal coliforms. The main risk factors for microbiological contamination in the region are extensive cattle ranching and the lack of adequate protection of the springs in most properties, with emphasis on the catchment areas of native grassland and native forest. Springs in pine forest areas have the lowest mean pH and the highest phenol content.
JOGOS EM REALIDADE AUMENTADA
Authors: De Freitas Vasconcelos Yuri , Rocha Lyra Maurício
Published: July 2018

É possível desenvolver um software em Realidade Aumentada capaz de projetar um vídeo em smartphones a partir do reconhecimento de marcadores? O software a ser desenvolvido é importante para o planejamento e execução de estratégias de marketing? A pesquisa é relevante para confirmar ou refutar estudos na área da Tecnologia da Informação? O objetivo desta pesquisa é de fato identificar se é possível desenvolver tal software de forma a afetar positivamente estratégias de marketing e, ao mesmo tempo, ser um estudo relevante para a área da Tecnologia da Informação. Para tal, foi realizada uma pesquisa de diversos softwares de produção em realidade aumentada e escolhido o Vuforia, que foi utilizado juntamente do software Unity, utilizada para o desenvolvimento de jogos. Foi desenvolvido, então, um aplicativo para Android que se utiliza da câmera do smartphone para visualizar o logotipo do UniCeub e exibir um vídeo promocional da instituição
SISTEMA PORTÁTIL PARA DIAGNÓSTICO E PROCESSAMENTO DA VARIABILIDADE DA FREQUÊNCIA CARDÍACA BASEADA NAS TRANSFORMADAS DE WAVELET E COM ENVIO DOS RESULTADOS VIA INTERNET
Authors: Molina Monteiro Hugo , Salomão Damião Nathalia , Henrique Duque Luciano
Published: July 2018

Este projeto propõe o desenvolvimento de um sistema portátil capaz de realizar medições dos sinais cardíacos e enviar os resultados, via internet, ao médico cardiologista. Em localidades remotas onde não existem equipamentos de eletrocardiografia ou cardiologistas, o sistema portátil proposto permitirá ao médico ou enfermeiro, não especialistas, realizarem o exame cardíaco de forma simples para posterior análise de um especialista. A simplicidade na realização do exame agiliza o processo de diagnóstico de um médico localizado distante do ponto de atendimento do paciente. O exame poderá ser realizado colocando os eletrodos do dispositivo portátil no peito do paciente. Os dados cardíacos são armazenados e enviados para localidades que possuam médicos especialistas. A captação do sinal cardíaco e sua análise de variabilidade serão realizadas de forma não-invasiva utilizando eletrodos de superfície. O dispositivo portátil terá também um visor em display de cristal líquido informando as ondas geradas. O sinal cardíaco captado apresenta valores de tensão baixos, inferior a 0,01Vpp (0,01 volts pico a pico) e, por isso, o processamento digital deverá ser realizado para eliminar os ruídos externos. Esse sinal será filtrado e amplificado com a utilização de amplificadores operacionais de alta sensibilidade e ganho. Após esse processo, as informações são enviadas para o microcontrolador que faz uso de um software para realizar as transformadas de Wavelet no tratamento dos sinais. A transformada de Wavelet decompõe os sinais cardíacos em uma função definida no domínio do tempo e em outra função, definida no domínio da frequência. Esse processamento será comandado por um microcontrolador que fará o tratamento do sinal, o armazenamento e o envio dos dados via internet
ANÁLISE DA CRIATIVIDADE NO CENÁRIO ESCOLAR E SUA EXPRESSÃO EM PRÁTICAS INOVADORAS
Authors: De Jesus Reis Telma , De Oliveira Campolina Luciana
Published: July 2018

Esta pesquisa faz parte do campo de estudo da psicologia e teve por objetivo investigaras características consideradas criativas dos professores que desenvolvem práticasinovadoras em uma instituição de ensino de nível superior. Esta investigação assumiucomo perspectiva teórica a Teoria da Subjetividade proposta por González Rey, na quala pessoa é compreendida como um ser histórico com desenvolvimento social e comosujeito ativo capaz de promover mudanças no contexto em que atua. A pesquisa foidesenvolvida a partir da Epistemologia Qualitativa, que por seus princípiosmetodológicos permitem a investigação das características do professor no contextoeducacional, construindo indicadores e hipóteses acerca da subjetividade destesprofissionais. Os instrumentos utilizados foram a observação das práticas inovadoras e adinâmica conversacional. O modelo teórico se embasou em uma construção hipotética,na qual consideramos que a atuação pedagógica dos professores se constitui a partir dedois principais indicadores comuns aos dois participantes da pesquisa, sendo aversatilidade dos recursos pedagógicos e a postura intencional e deliberada em relação asua produção pedagógica em favor do aprendizado dos alunos. Concluímos destacandoa importância dos recursos pedagógicos inovadores, quando são pensados dentro e parao contexto escolar, a partir de um processo dialógico entre o professor-aluno, momentosem que ocorrem trocas e negociações que produzem nos envolvidos uma posturacriativa, ativa e reflexiva. Ressaltamos, também, a relevância da emocionalidade nocontexto educacional, a qual não está relacionada com a materialização dos recursospedagógicos em si, mas sim com a produção subjetiva do professor
DIAGRAMA: SÍNTESE CONCEITUAL E ESTRATÉGIA PROJETUALENSAIOS ANALÍTICOS SOBRE A ARQUITETURA CONTEMPORÂNEA
Authors: Letícia Siqueira Seibel Amanda , José Arcadio Sobreira Fabiano
Published: July 2018

Esta pesquisa teve como objetivo a análise do uso do diagrama na arquitetura contemporânea, sob a ótica de concursos de projeto nacionais e internacionais. Como meotodologia foi realizada a catalogação dos diagramas por projeto, através das pranchas disponibilizadas pelos concorrentes, com análises preliminares a respeito do caráter analítico ou propositivo desses elementos gráficos, sobre a recorrência de seu uso e a consecutiva relação com o conjunto programático do concurso. Foram realizados fichamentos, visando propor classificações em relação à natureza dos diagramas de cada concurso, englobando classificações independentes da posição em relaçao ao resultado final do concurso. Foram realizados estudos analíticos em relação aos diagramas utilizados em cinco concursos, de projetos premiados e menções, objetivando traçar um olhar mais detalhado a respeito das classificações e variações de tais recursos gráficos, especificamente em relação às abordagens analíticas resultantes: temática, processo e natureza, apresentando assim relações importantes no estabelecimento de diálogos entre diagramas e suas escolhas projetuais. Observou-se que o diagrama, além de um instrumento descritivo e explicativo, apresenta possibilidades compositivas como parte do processo projetual e não apenas do produto. A leitura e a análise de projetos contemporâneos sob a perspectiva da expressão diagramática nos oferecem uma série de reflexões e inquietações, entre as quais destacamos a discussão sobre os limites entre a produção de diagramas arquitetônicos e a promoção de uma arquitetura diagramática. Em alguns casos a retórica apenas confirma ou evidencia estratégias de composição (espacial e volumétrica) desenvolvidas ao longo do processo de concepção e desenvolvimento: percebe-se, nesses casos, um equilíbrio entre o que foi projetado e o que está sendo comunicado. Em outros casos, a retórica é fabricada a posteriori, como um recurso de comunicação, não necessariamente vinculado ao exercício de projeto. Neste grupo incluímos as tentativas retóricas de agregar conteúdo e apelo visual a projetos que não nasceram de reflexões diagramáticas
OS PROCESSOS SUBJETIVOS PRODUZIDOS POR UMA PESSOA DIAGNOSTICADA COM SÍNDROME DO PÂNICO: A SINGULARIDADE DA EXPERIÊNCIA
Authors: Carolina Arruda Penna Ana , Deusdará Mori Valéria
Published: July 2018

Essa pesquisa é um fruto de uma análise qualitativa dos processos subjetivos dentro de um enfoque singular. Esse foi um estudo embasado na Teoria da Subjetividade e na Epistemologia Qualitativa desenvolvida por González Rey, na qual a produção de conhecimento possui três características: a primeira é a importância do singular no processo, ou seja, há uma valorização da experiência subjetiva para se compreender o contexto da pesquisa; a segunda é o caráter construtivo interpretativo do conhecimento, onde ele é uma produção teórica do pesquisador além do momento empírico; como terceira característica e onde essa pesquisa se fundamenta é assimilar a pesquisa como um processo de comunicação, um processo dialógico no qual por meio da expressão o participante emerge os diferentes sentidos subjetivos que ele produz. O objetivo principal dessa pesquisa foi compreender os processos subjetivos que se caracterizam na experiência da síndrome do pânico, tendo como foco a singularidade desse processo e o conceito de pessoa como produtora de sentidos de sua própria vivência. Diante dessa perspectiva foi abordado as particularidades do processo de saúde e doença dentro de uma perspectiva singular a patologização da pessoa diante do discurso médico vigente, reduzindo a pessoa à entidade patológica, ignorando os processos singulares de cada um. O método utilizado foi o método construtivo-interpretativo elaborado por González Rey. A pesquisa foi desenvolvida com um estudo de caso com uma mulher de 31 anos que foi diagnosticada com síndrome do pânico. Os instrumentos de pesquisa utilizados foram a dinâmica conversacional e o complemento de frases. Na discussão os instrumentos foram o que possibilitaram a interpretação da expressão da participante e assim possibilitaram compreender os sentidos subjetivos que norteiam esse processo singular da doença. Como resultados foi possível observar que a subjetividade social dominante, que prega por um conceito patológico fixo e constante, se fez constantemente presente na expressão da participante, o que acaba por reduzi-la à doença e minimizando sua posição diante do processo. A pesquisa possibilitou um olhar aprofundado para os discursos sociais atuais e que se pautam na clínica médica, onde um problema que, aparentemente, se organiza pontualmente pode ser tratado pontualmente. O tratamento de sintomas não auxilia a pessoa a pensar sobre sua condição e sua possibilidade de se posicionar diante dela, o que muitas vezes traz contradições na experiência
ANÁLISE EPIDEMIOLÓGICA DOS ÁRBITROS BRASILEIROS E EFETIVIDADE DO PROGRAMA DE PREVENÇÃO DE LESÕES FIFA 11+/ VERSÃO PARA ÁRBITROS APLICADO NOS MEMBROS DA FEDERAÇÃO BRASILIENSE DE FUTEBOL
Authors: Henrique Crema Duarte Pedro , De Paula Oliveira Marcio
Published: July 2018

O futebol, devido ao alto nível de exigência por parte dos atletas e árbitros, está associado a diferentes lesões. Para os atletas, a literatura é vasta no que diz respeito aos tipos e repercussões destas intercorrências. No entanto, faltam informações acerca das características dos árbitros, bem como dos resultados da aplicação de programas específicos prevenção de lesões nessa população. Nesse sentido, o presente estudo descreve as características epidemiológicas dos árbitros brasileiros e os resultados da avaliação da efetividade da aplicação do Programa de Prevenção de Lesões FIFA 11+/ versão para árbitros nos membros da Federação Brasiliense de Futebol (FBF). Foram estudados 66 árbitros de ambos os gêneros, com média de idade 32,95 anos, provenientes de federações das diferentes regiões brasileiras. Eram de diferentes níveis de atuação e apresentavam o tempo médio de 8,82 anos de experiência. 22 destes membros da FBF, foram submetidos ao programa de prevenção de lesões duas vezes por semana, durante o período de 11 meses e avaliados quanto à funcionalidade e ocorrência de lesões antes e após a intervenção. Os resultados encontrados demonstraram um elevado número de lesões nos participantes, assim como a melhora significativa da funcionalidade e redução do número de lesões durante o período de acompanhamento. Concluiu-se que a participação no Programa de Prevenção de Lesões FIFA 11+/ versão para árbitros promoveu uma melhora considerável no grupo estudado
AVALIAÇÃO DO CONHECIMENTO DE PROFISSIONAIS DA SAÚDE QUANTO À CAMPANHA DO ALERTA AMARELO E CONDUTA NA COLESTASE NEONATAL
Authors: Luísa Neiva Melo Ana , Costa Moreira Nayra , De Carvalho Elisa
Published: July 2018

A elevação da bilirrubina direta em recém-nascidos e lactentes (colestase neonatal) traduz a diminuição da secreção biliar por doença hepatocelular ou biliar, precisando de exploração clínica urgente. Dentre as causas da icterícia patológica em crianças, a atresia biliar (AB) é a principal delas, e necessita de correção cirúrgica antes dos 60 dias de vida. (BEZERRA, 2010). O prognóstico e a sobrevida dos pacientes têm influência direta do diagnóstico precoce, tendo em vista, que o diagnóstico tardio se relaciona à necessidade de transplante hepático ou morte nos primeiros 3 anos de vida (CARVALHO, 2010). As razões para os atrasos na detecção da AB estão possivelmente relacionadas com aspectos, como conhecimento sobre a doença na comunidade, reconhecimento da doença por profissionais de saúde de atenção básica e acesso a atendimento especializado (CARVALHO, 2010). Nesse contexto, o presente trabalho tem como objetivo avaliar o conhecimento de profissionais de saúde do Distrito Federal quanto ao diagnóstico, seguimento adequado da colestase neonatal e quanto à campanha do Alerta Amarelo. O método utilizado consistiu-se de busca ativa de profissionais da área de pediatria para resposta de questionário nas Unidades de Saúde da SES-DF. Foram entrevistados 93 pediatras, 69 residentes e 43 enfermeiros, totalizando 203 profissionais. Do total, 49,47% julgaram não conhecer a campanha do alerta amarelo, e 37,07% não tem conhecimento sobre a cartela de coloração das fezes na caderneta de saúde da criança. É possível perceber que ainda existe grande desinformação sobre a campanha do alerta amarelo, influenciando o encaminhamento e o diagnostico tardios de pacientes com Atresia Biliar
ESTUDO DO POLIMORFISMO E DIAGNÓSTICO MOLECULAR DO GENE CAUSADOR DA NEOPLASIA ENDÓCRINA MÚLTIPLA TIPO 2B
Authors: De Brito Monteiro Lauar , Freitas da Costa Daniel , Roberto Queiroz Paulo
Published: July 2018

A neoplasia endócrina múltipla tipo 2B é uma desordem de caráter autossômicodominante e é também a variante mais agressiva de todas as neoplasias endócrinasmúltiplas. Ela é causada por mutações de linhagem germinativa que induzem ganhode função do proto-oncogeneRET, responsável por codificar uma proteína do tipotirosina quinase que proporciona o controle da proliferação, diferenciação, migração eapoptose celular de células derivadas da crista neural. Aproximadamente metade doscasos são causados por mutações de novo no gene, portanto não possuem históricofamiliar. Entretanto, o rastreio genético para esta doença em grupos de risco consistena busca por mutações no proto-oncogeneRET durante os primeiros anos de vida. Oobjetivo desta pesquisa foi determinar o polimorfismo e a frequência do gene causadorda neoplasia endócrina múltipla tipo 2B em um grupo de indivíduos fumantes pormétodo molecular e definir padrões de influência genética e ambiental noaparecimento de mutações no gene RET.Primeiramente houve a produção de umartigo de revisão listando os mecanismos moleculares do gene de interesse e osprincipais métodos de rastreio e diagnóstico bioquímico e genético. A segunda partedo estudo realizado contou com a participação de vinte voluntários fumantes queestavam de acordo com o Termo de Consentimento Livre e Esclarecido proposto peloComitê de Ética. Foi encontrado um perfil de normalidade nas análises bioquímicas ehematológicas dos indivíduos e o questionário de controle de qualidade de vidarevelou que os voluntários se expõem com frequência à radiação solar e não mantêmum estilo de vida saudável, fatores que predispõem o aparecimento de mutações nogenoma. A análise por PCR-RFLP seguida de eletroforese em gel de agarose domaterial genético dos participantes não revelou a presençada mutação causadora daneoplasia endócrina múltipla tipo 2B
Hallmark of success: top 50 classics in oral and maxillofacial cone-beam computed tomography
Authors: Wu Yuhao , Tiwana Haaris , Durrani Mariyam , Tiwana Sabeen , Gong Bo , Hafeez Kashif , Khosa Faisal
Published: July 2018

Purpose

The aim of this study was to identify the top 50 cited articles on the use of cone-beam computed tomography (CBCT) for oral and maxillofacial applications and to summarise the characteristics of the most impactful research articles in this domain.

Material and methods

A database was generated by combining the search results from Thomson Reuters Web of Science and Elsevier’s Scopus to ensure that all top-cited publications were captured. We used three search fields to generate the database: 1) CBCT, 2) oral and maxillofacial pathologies, and 3) oral and maxillofacial anatomical structures. Publications were then ranked by citation counts and reviewed by two independent reviewers.

Results

A total of 50 top publications were included in the study. Their citation count ranged from 43 to 170 with a median of 55.5. Five publications were cited more than 100 times. All except for one paper were published after 2000. The most well published journal was the American Journal of Orthodontics and Dentofacial Orthopedics (n = 12), and the United States of America (n = 15) was the most productive country in the field. The majority of the studies (n = 27) discussed the imaging of primary tooth pathologies, but there are also a significant number of articles that discuss imaging of bone grafts or dental implants (n = 7), upper airways (n = 5), the skull (n = 4), and other maxillofacial structures (n = 7).

Conclusions

Our study identifies 50 research articles with the highest number of citations in oral and maxillofacial CBCT, discusses the characteristics and commonalities between these articles, and predicts future trends in the field.
Inter-observer agreement of the Coronary Artery Disease Reporting and Data System (CAD-RADSTM) in patients with stable chest pain
Authors: Razek Ahmed Abdel Khalek Abdel , Elrakhawy Mohamed Magdy , Yossof Mahmoud Mohamed , Nageb Hadeer Mohamed
Published: July 2018

Purpose

To assess inter-observer variability of the Coronary Artery Disease – Reporting and Data System (CAD-RADS) for classifying the degree of coronary artery stenosis in patients with stable chest pain.

Material and methods

A prospective study was conducted upon 96 patients with coronary artery disease, who underwent coronary computed tomography angiography (CTA). The images were classified using the CAD-RAD system according to the degree of stenosis, the presence of a modifier: graft (G), stent (S), vulnerable plaque (V), or non-diagnostic (n) and the associated coronary anomalies, and non-coronary cardiac and extra-cardiac findings. Image analysis was performed by two reviewers. Inter-observer agreement was assessed.

Results

There was excellent inter-observer agreement for CAD-RADS (k = 0.862), at 88.5%. There was excellent agreement for CAD-RADS 0 (k = 1.0), CAD-RADS 1 (k = 0.92), CAD-RADS 3 (k = 0.808), CAD-RADS 4
(k = 0.826), and CAD-RADS 5 (k = 0.833) and good agreement for CAD-RADS 2 (k = 0.76). There was excellent agreement for modifier G (k = 1.0) and modifier S (k = 1.0), good agreement for modifier N (k = 0.79), and moderate agreement for modifier V (k = 0.59). There was excellent agreement for associated coronary artery anomalies (k = 0.845), non-coronary cardiac findings (k = 0.857), and extra-cardiac findings (k = 0.81).

Conclusions

There is inter-observer agreement of CAD-RADS in categorising the degree of coronary arteries stenosis, and the modifier of the system and associated cardiac and extra-cardiac findings.
Reviewer Acknowledgements for Journal of Educational Issues, Vol. 4, No. 1
Authors: Ann Priscilla
Published: July 2018

Reviewer acknowledgements for Journal of Educational Issues, Vol. 4, No. 1, 2018.
Nursing students’ knowledge about Alzheimer’s disease
Authors: Wiese Lisa Kirk , Williams Christine Lynn
Published: July 2018

Objective: Every 66 seconds a U.S. resident develops Alzheimer’s disease (AD). Future nurses will be caring for the rapidly escalating number of adults turning 65, yet information regarding nursing students’ knowledge about the age-related disease of Alzheimer’s is limited. The purpose of this study was to examine 102 Florida baccalaureate nursing students’ basic and advanced AD knowledge.Methods: A descriptive design using two AD knowledge measures and analysis using paired samples t-test were employed.Results: Although the setting was a region of the U.S. with the highest percentage of older adults, knowledge deficits regarding age-related Alzheimer’s disease were striking. Students’ basic knowledge was significantly higher than their advanced AD knowledge (t(101) = 2.28, p = .027). Only 31% of students identified that high cholesterol may increase risk. Just 20% of students correctly answered that exercise does not prevent AD. About 25% correctly responded that the average life expectancy after the onset of AD is 6-12 years. Only 2% of nursing students correctly identified that persons with AD experience stress from disease-related symptoms. Overall, less than 50% of students correctly answered any item on the measure designed for use among health care providers.Conclusions: To better prepare nursing students to care for the increasing numbers of older adults facing risk of AD, updated curricula targeting dementia-related illnesses are essential. Information is offered regarding current state of the science resources of benefit to faculty, students, and practicing nurses, such as experiential learning and Hartford Institute of Geriatric Nursing collaborative programs.
Being there at a distance: Connecting the academic library to students who study abroad
Authors: Emmelhainz Celia , Pukkila Marilyn R.
Published: July 2018

Like many liberal arts colleges, Colby College prides itself on its global focus, opportunities for undergraduate research, and the high number of students who study abroad during their junior year of college. Because of this, we as reference and research librarians wanted to better connect with our students abroad—students who often go off the radar in the intimate campus-focused environment of a small academic library. In this article, we’d like to talk about our outreach to students before and during study abroad, our assessment of its effects, and what we learned.
C&RL Spotlight
Authors: Kaspar Wendi
Published: July 2018

One of the primary roles of an editor is to support research and writing. This can be an explicit activity in the form of coordinating the journal, managing the review process, and editing the articles and issues. It can also be a more informal effort that focuses on development and intentionally engaging readers and authors about the writing or research processes. The editorials are a useful venue for such an endeavor. C&RL readers will find that many of the past editorials, those written by me or by guests, seek to engage in topics that will make the research, writing, and editorial processes more transparent as well as providing useful perspectives for authors and researchers. The guest editorial for July follows this trend. “Collaborative Authorship as Peer Mentorship” by Courtney Jacobs, Marcia McIntosh, and Kevin M. O’Sullivan describes the lessons learned in their collaboration and addresses effective practice in projects that may be operational or organizational in nature and in research efforts that may ultimately result in shared publication.
Fast Facts
Authors: Pattillo Gary
Published: July 2018

Trends in college pricingWhat3Words—online mappingProjections of education statisticsWikipedia editorsAutomated fact checking
Students' Conceptions of Sine and Cosine Functions When Representing Periodic Motion in a Visual Programming Environment
Authors: DeJarnette Anna F.
Published: July 2018

In support of efforts to foreground functions as central objects of study in algebra, this study provides evidence of how secondary students use trigonometric functions in contextual tasks. The author examined secondary students' work on a problem involving modeling the periodic motion of a Ferris wheel through the use of a visual programming environment. This study illustrates the range of prior knowledge and resources that students may draw on in their use of trigonometric functions as well as how the goals of students' work inform their reasoning about trigonometric functions.
Pain Mechanisms and Ultrasonic Inflammatory Activity as Prognostic Factors in Patients With Psoriatic Arthritis: A Prospective Cohort Study
Authors: Højgaard Pil , Ellegaard Karen , Nielsen Sabrina Mai , Christensen Robin , Guldberg‐Møller Jørgen , Ballegaard Christine , Dreyer Lene , Mease Philip , de Wit Maarten , Skov Lone , Glintborg Bente , Bliddal Henning , Bartels Else Marie , Amris Kirstine , Kristensen Lars Erik
Published: July 2018

Objective

To study the prognostic value of widespread pain and of musculoskeletal ultrasound (US) examination for subsequent treatment outcomes in patients with psoriatic arthritis (PsA).

Methods

An exploratory prospective cohort study enrolled patients with PsA initiating biologic or conventional synthetic disease‐modifying antirheumatic drugs in routine care. Clinical, US, and patient‐reported measures were collected at baseline and after 4 months. Widespread nonarthritic pain (WP) was defined as a Widespread Pain Index score of ≥4 with pain in ≥4 of 5 regions. PsA activity by US was defined as color Doppler (yes/no) in selected entheses, joints, or tendons. The main response criteria included the American College of Rheumatology 20% improvement, the Disease Activity in Psoriatic Arthritis 50% improvement, and minimal disease activity. The primary analyses were age‐ and sex‐adjusted logistic regression.

Results

WP was present in 24 of 69 included patients (35%) and was associated with worse patient‐reported and composite baseline measures, while US and other objective findings were similar to those in patients without WP. The odds of reaching minimal disease activity after 4 months were significantly greater for patients enrolled without WP (odds ratio 18.43 [95% confidence interval 1.51, 224.41]; P = 0.022), while WP did not impair other response measures. Patients with baseline color Doppler activity (n = 42 [61%]) had a worse objective PsA burden, but their chance of treatment response was comparable to those without color Doppler.

Conclusion

More than one‐third of patients with PsA presented with WP, which was associated with worse patient‐reported scores and failure to achieve minimal disease activity following conventional synthetic or biologic disease‐modifying antirheumatic drug therapy. PsA activity by color Doppler US had no influence on subsequent treatment response in this PsA cohort.
Body Fat Percentage, Waist Circumference, and Obesity As Risk Factors for Rheumatoid Arthritis: A Danish Cohort Study
Authors: Linauskas Asta , Overvad Kim , Symmons Deborah , Johansen Martin B. , Stengaard‐Pedersen Kristian , de Thurah Annette
Published: July 2018

Objective

To investigate the relationship between bioimpedance‐derived total body fat percentage, waist circumference, and body mass index (BMI) and the subsequent development of rheumatoid arthritis (RA).

Methods

A population‐based prospective cohort study was conducted using 55,037 patients enrolled in the Danish Diet, Cancer, and Health cohort. Baseline data included anthropometric measures and lifestyle factors. Individuals who developed RA were identified through linkage with the Danish National Patient Registry. The relationships between bioimpedance‐derived body fat percentage, waist circumference, and BMI and incident RA were assessed using Cox proportional hazards regression models, stratifying by sex. All analyses were performed for overall RA and the serologic subtypes seropositive and other RA.

Results

A total of 210 men (37.6% with seropositive RA) and 456 women (41.0% with seropositive RA) developed RA during a median follow‐up of 20.1 years. In women, the overall RA risk was 10% higher for each 5% increment of total body fat (hazard ratio [HR] 1.10 [95% confidence interval (95% CI) 1.02–1.18]), 5% higher for each 5‐cm increment of waist circumference (HR 1.05 [95% CI 1.01–1.10]), and nearly 50% higher in those whose BMI was in the obese range compared to normal range BMI (HR 1.46 [95% CI 1.12–1.90]). These positive associations were also found for patients with other RA. In men, there were no clear associations between body fat percentage, waist circumference, or BMI and RA. No significant associations were found for seropositive RA in women or men, possibly related to low sample size.

Conclusion

In women, higher body fat percentage, higher waist circumference, and obesity were associated with a higher risk of RA.
Novel Electronics for Flexible and Neuromorphic Computing
Authors: Lee Han Eol , Park Jung Hwan , Kim Tae Jin , Im Doyoung , Shin Jung Ho , Kim Do Hyun , Mohammad Baker , Kang Il‐Suk , Lee Keon Jae
Published: July 2018

Emerging classes of flexible electronic systems that can be attached to a wide range of surfaces from wearable clothes to internal organs have driven significant advances in communication protocols (e.g., Internet of Things, augmented reality) and clinical research, shifting today's personal computing paradigm. The field of “system on plastic” is on the verge of an innovative breakthrough toward a hypercognitive society by being fused with current neuromorphic applications in the spotlight, which can offer intelligent services such as personalized feedback therapy and autonomous driving. The novel concept of electronics for flexible and neuromorphic computing requires an important research leap in micro‐/nanoelectronics on plastics, system‐level integration techniques (interconnection and packaging), and synaptic devices. Here, representative advances and developments in the area of flexible and neuromorphic technologies are reviewed with regard to device configurations, materials, fabrication processes, and their potential research fields.