bluuebunny/crossref_metadata_2025 huggingface dataset:
The journey is just as important as the destination—Digital neuropsychological assessment provides performance stability measures in patients with acquired brain injury
Authors: Spreij Lauriane A. , Gosselt Isabel K. , Visser-Meily Johanna M. A. , Hoogerbrugge Alex J. , Kootstra Timo M. , Nijboer Tanja C. W.
Published: July 2021

Background

Cognitive performances on neuropsychological paper-and-pencil tests are generally evaluated quantitatively by examining a final score (e.g., total duration). Digital tests allow for a quantitative evaluation of “how” a patient attained a final score, which opens the possibility to assess more subtle cognitive impairment even when final scores are evaluated as normal. We assessed performance stability (i.e., the number of fluctuations in test performance) to investigate (1) differences in performance stability between patients with acquired brain injury (ABI) and healthy controls; (2) the added value of performance stability measures in patients with ABI; and (3) the relation between performance stability and cognitive complaints in daily life in patients with ABI.

Methods

We administered three digital neuropsychological tests (Rey Auditory Verbal Learning Test, Trail Making Test, Stroop Colour and Word Test) and the Cognitive Complaints—Participation (CoCo-P) inventory in patients with ABI (n= 161) and healthy controls (n= 91).

Results

Patients with ABI fluctuated more in their performance on all tests, when compared to healthy controls. Furthermore, 4–15% of patients who performed inside normal range on the conventional final scores were outside normal range on the performance stability measures. The performance stability measures, nor the conventional final scores, were associated with cognitive complaints in daily life.

Conclusions

Stability in test performance of patients was clearly dissociable from healthy controls, and may assess additional cognitive weaknesses which might not be observed or objectified with paper-and-pencil tests. More research is needed for developing measures better associated with cognitive complaints.
Taking a critical stance towards mixed methods research: A cross-disciplinary qualitative secondary analysis of researchers’ views
Authors: Fàbregues Sergi , Escalante-Barrios Elsa Lucia , Molina-Azorin José Francisco , Hong Quan Nha , Verd Joan Miquel
Published: July 2021

Recent growth and institutionalization in the field of mixed methods research has provided fertile ground for a wide range of thoughtful criticism of how this research approach has been developed and conceptualized by some members of the mixed methods community. This criticism reflects the increasing maturity of the field as well as the different theoretical perspectives and methodological practices of researchers in different disciplines. While debates addressing these criticisms are likely to lead to valuable insights, no empirical studies have been carried out to date that have investigated researchers’ critical views on the development and conceptualization of mixed methods research. This study examines the criticisms of the mixed methods field raised by a cross-national sample of researchers in education, nursing, psychology, and sociology. We carried out a secondary analysis of semi-structured interviews with 42 researchers and identified 11 different criticisms, which we classified in four domains: essence of mixed methods, philosophy, procedures, and politics. The criticisms related to the procedures domain were equally distributed among the four disciplines, while those related to the essence, philosophy and politics domains were more common among sociologists. Based on our findings, we argue that the divergence of views on foundational issues in this field reflects researchers’ affiliation to different communities of practice, each having its own principles, values, and interests. We suggest that a greater awareness of this divergence of perspectives could help researchers establish effective collaboration and anticipate potential challenges when working with researchers having different methodological approaches.
Shotgun proteomics of Brassica rapa seed proteins identifies vicilin as a major seed storage protein in the mature seed
Authors: Rahman Mahmudur , Guo Qi , Baten Abdul , Mauleon Ramil , Khatun Amina , Liu Lei , Barkla Bronwyn J.
Published: July 2021

Proteins make up a large percentage of the Brassica seed and are second only to the oil in economic importance with uses for both animal and human nutrition. The most abundant proteins reported in the seeds of Brassica are the seed storage proteins cruciferin and napin, belonging to the 12S globulin and 2S albumin families of proteins, respectively. To gain insight into the Brassica rapa seed proteome and to confirm the presence and relative quantity of proteins encoded by candidate seed storage genes in the mature seed, shotgun proteomics was carried out on protein extracts from seeds of B. rapa inbred line R-o-18. Following liquid chromatography tandem mass spectrometry, a total of 34016 spectra were mapped to 323 proteins, where 233 proteins were identified in 3 out of 4 biological replicates by at least 2 unique peptides. 2S albumin like napin seed storage proteins (SSPs), 11/12S globulin like cruciferin SSPs and 7S globulin like vicilin SSPs were identified in the samples, along with other notable proteins including oil body proteins, namely ten oleosins and two oil body-associated proteins. The identification of vicilin like proteins in the mature B. rapa seed represents the first account of these proteins in the Brassicaceae and analysis indicates high conservation of sequence motifs to other 7S vicilin-like allergenic proteins as well as conservation of major allergenic epitopes in the proteins. This study enriches our existing knowledge on rapeseed seed proteins and provides a robust foundation and rational basis for plant bioengineering of seed storage proteins.
Age- and sex-associated differences in hematology and biochemistry parameters of Dunkin Hartley guinea pigs (Cavia porcellus)
Authors: Spittler Alexa P. , Afzali Maryam F. , Bork Sydney B. , Burton Lindsey H. , Radakovich Lauren B. , Seebart Cassie A. , Moore A. Russell , Santangelo Kelly S.
Published: July 2021

The Dunkin Hartley is the most common guinea pig strain used in biomedical research, particularly for studies of asthma, allergy, infectious disease, reproduction, and osteoarthritis. Minimally invasive blood tests, such as complete blood counts and serum biochemistry profiles, are often collected for diagnostics and laboratory analyses. However, reference intervals for these assays have not yet been well-documented in this strain. The purpose of this study was to establish reference intervals for hematologic and biochemical parameters of Dunkin Hartley guinea pigs and determine age- and sex-related differences. Hematologic and biochemical parameters were retrospectively obtained from 145 male and 68 female guinea pigs between 2 and 15 months of age. All blood parameters were analyzed by a veterinary clinical pathology laboratory. Reference intervals were established according to the American Society for Veterinary Clinical Pathology guidelines. Age- and sex-related differences were determined using unpaired t-tests or nonparametric Mann-Whitney tests. Hematocrit, red blood cell distribution width, mean platelet volume, white blood cell count, heterophils, monocytes, eosinophils, glucose, blood urea nitrogen, creatinine, calcium, magnesium, total protein, albumin, globulin, cholesterol, aspartate aminotransferase, gamma glutamyl transferase, and bicarbonate increased with age. Mean corpuscular hemoglobin concentration, cellular hemoglobin concentration mean, platelets, lymphocytes, phosphorus, albumin/globulin ratio, alkaline phosphatase, anion gap, and calculated osmolality decreased with age. Males had higher hemoglobin, hematocrit, red blood cell count, mean corpuscular hemoglobin concentration, white blood cell count, heterophils, Foa-Kurloff cells, alanine aminotransferase, and bicarbonate and lower mean corpuscular volume, red blood cell distribution width, platelets, mean platelet volume, eosinophils, total protein, albumin, globulin, cholesterol, potassium, anion gap, calculated osmolality, and iron compared to females. Establishing age and sex differences in hematologic and biochemical parameters of Dunkin Hartley guinea pigs provides valuable insight into their physiology to better evaluate diagnostics and experimental results.
Control strategies against COVID-19 in China: Significance of effective testing in the long run
Authors: Lin Yatang , Peng Fangyuan
Published: July 2021

The COVID-19 pandemic has become a long-term crisis that calls for long-term solutions. We combined an augmented SEIR simulation model with real-time human mobility data to decompose the effects of lockdown, travel bans and effective testing measures in the curtailment of COVID-19 spread in China over different time horizons. Our analysis reveals that the significant growth in the detection rate of infectious cases, thanks to the expansion in testing efficiency, were as effective as city lockdowns in explaining the reduction in new infections up to mid-March. However, as we extended the analysis to July, increasing the detection rate to at least 50% is the only reliable way to bring the spread under control.
Composition Wheels: Visualizing dissolved organic matter using common composition metrics across a variety of Canadian ecozones
Authors: Aukes Pieter J. K. , Schiff Sherry L.
Published: July 2021

Dissolved organic matter (DOM) is a ubiquitous component of aquatic systems, impacting aquatic health and drinking water quality. These impacts depend on the mixture of organic molecules that comprise DOM. Changing climates are altering both the amount and character of DOM being transported from the terrestrial system into adjacent surface waters, yet DOM composition is not monitored as often as overall concentration. Many DOM characterization methods exist, confounding comparison of DOM composition across different studies. The objective of this research is to determine which parameters in a suite of relatively simple and common DOM characterization techniques explain the most variability in DOM composition from surface and groundwater sites. Further, we create a simple visualization tool to easily compare compositional differences in DOM. A large number of water samples (n = 250) was analyzed from six Canadian ecozones for DOM concentration, ultraviolet-visible light absorbance, molecular size, and elemental ratios. Principal component analyses was used to identify quasi-independent DOM compositional parameters that explained the highest variability in the dataset: spectral slope, specific-UV absorbance at 255nm, humic substances fraction, and dissolved organic carbon to dissolved organic nitrogen ratio. A ‘Composition Wheel’ was created by plotting these four parameters as a polygon. Our results find similarities in DOM composition irrespective of site differences in vegetation and climate. Further, two main end-member Composition Wheel shapes were revealed that correspond to DOM in organic-rich groundwaters and DOM influenced by photodegradation. The Composition Wheel approach uses easily visualized differences in polygon shape to quantify how DOM evolves by natural processes along the aquatic continuum and to track sources and degradation of DOM.
Operation mode selection of NIMBY facility Public Private Partnership projects
Authors: Zhao Hui , Zhang Jingqi , Ge Yuanyuan
Published: July 2021

Construction of not in my back yard (NIMBY) facility Public Private Partnership (PPP) projects are feasible measures to realize sustainable urbanization. In order to ensure the smooth development of the NIMBY facility PPP projects, the problem of choosing the most suitable operation mode among many PPP modes is still scarce and unscientific. In order to select the operation mode of the PPP projects that best fits the characteristics of the project, this paper constructs the operation mode selection of the NIMBY facility PPP project. Firstly, the index system of operation mode selection of the NIMBY facility PPP project is determined. G1 subjective weighting method and information entropy objective weighting method are introduced to solve the optimal weight of each index. Grey correlation theory is used to improve TOPSIS method, and the calculation form of relative proximity degree is optimized to determine the most suitable operation mode for the project. In this paper, combined weighting and TOPSIS method are applied to the research of NIMBY facility PPP project, and the operation mode selection of NIMBY facility PPP project is established, which makes up the blank of this part. Finally, a PPP project in Qingdao, Shandong Province, China, is taken as an example to verify the applicability of the model. The effectiveness of this model was tested by comparing the results of TOPSIS method, Grey target model, Extended matter-element mode and GRA-TOPSIS. It is hoped to provide useful reference for the operation mode selection of NIMBY facility PPP project.
Telemedicine interventions for hypertension management in low- and middle-income countries: A scoping review
Authors: Hoffer-Hawlik Michael , Moran Andrew , Zerihun Lillian , Usseglio John , Cohn Jennifer , Gupta Reena
Published: July 2021

Hypertension remains the leading cause of cardiovascular disease worldwide and disproportionately impacts patients living in low- and middle-income countries (LMICs). Telemedicine offers a potential solution for improving access to health care for vulnerable patients in LMICs.

Objectives

The purpose of this scoping review was to summarize the evidence for telemedicine interventions for blood pressure management in LMICs and assess the relationships between the telemedicine intervention characteristics and clinical outcomes.

Design

Published studies were identified from the following databases (from their inception to May 2020): PubMed, Scopus, and Embase. Search terms related to “Low and Middle Income Countries,” “Telemedicine,” and “Hypertension” were used, and clinical outcomes were extracted from the screened articles.

Results

Our search resulted in 530 unique articles, and 14 studies were included in this review. Five studies assessed telemedicine interventions for patient-provider behavioral counseling, four assessed patient-provider medical management, and five assessed provider-provider consultation technologies. Out of fourteen individual studies, eleven demonstrated a significant improvement in systolic or diastolic blood pressure in the intervention group. Of the eight studies that reported difference-in-differences changes in systolic blood pressure, between-arm differences ranged from 13.2 mmHg to 0.4 mmHg.

Conclusions

The majority of the studies in this review demonstrated a significant reduction in blood pressure with use of the telemedicine intervention, though the magnitude of benefit was not consistently large. Limitations of the studies included small sample sizes, short duration, and intervention heterogeneity. Current evidence suggests that telemedicine may provide a promising approach to increase access to care and improve outcomes for hypertension in LMICs, especially during events that limit access to in-person care, such as the COVID-19 pandemic. However, high-quality clinical trials of sufficient size and duration are needed to establish the impact and role of telemedicine in hypertension care. The protocol for this review was not registered.
Carbon stocks of above- and belowground tree biomass in Kibate Forest around Wonchi Crater Lake, Central Highland of Ethiopia
Authors: Meragiaw Misganaw , Woldu Zerihun , Martinsen Vegard , Singh Bal Ram
Published: July 2021

Forests play an important role in the global carbon (C) balance, but their biomass has decreased globally mainly because of deforestation and a reduction in forest cover. However, little is known about the C stock of tree biomass related to environmental factors in the remnant forest patches. Thus, the present study aimed at assessing the status of C stocks of tree biomass using an allometric equation in Kibate Forest (Ethiopia). Sixty–six plots (30×30 m) were laid out at 100 m interval distance along the altitudinal gradients in five transects. The results revealed that the highest C stocks (67.4%) per species were contributed by Juniperus procera, Ilex mitis var. mitis, Nuxia congesta, and Olea europaea subsp. cuspidata. The mean total tree biomass was 91.9 ± 10.01 Mg ha−1. The mean total C stock was 45.9 ± 5.17 Mg ha−1, out of which 38.3 ± 4.31 and 7.7 ± 0.91 Mg ha−1 were stored in above- and belowground C pools, respectively. Anthropogenic factors were negatively associated with the C-stock distribution in the study area. Thus, the status of the C stock of tree biomass related to anthropogenic factors indicates that sustainable forest management practice is needed in the study area to conserve biodiversity and mitigate climate change.
Sperm-binding regions on bovine egg zona pellucida glycoprotein ZP4 studied in a solid supported form on plastic plate
Authors: Dilimulati Kamila , Orita Misaki , Undram Ganbat , Yonezawa Naoto
Published: July 2021

The zona pellucida (ZP) is a transparent envelope that surrounds the mammalian oocyte and mediates species-selective sperm–oocyte interactions. The bovine ZP consists of the glycoproteins ZP2, ZP3, and ZP4. Sperm-binding mechanisms of the bovine ZP are not yet fully elucidated. In a previous report, we established the expression system of bovine ZP glycoproteins using Sf9 insect cells and found that the ZP3/ZP4 heterocomplex inhibits the binding of sperm to the ZP in a competitive inhibition assay, while ZP2, ZP3, ZP4, the ZP2/ZP3 complex, and the ZP2/ZP4 complex do not exhibit this activity. Here, we show that bovine sperm binds to plastic plates coated with ZP4 in the absence of ZP3. We made a series of ZP4 deletion mutants to study the sperm-binding sites. The N-terminal region, Lys-25 to Asp-136, and the middle region, Ser-290 to Lys-340, of ZP4 exhibit sperm-binding activity. These results suggest that among the three components of bovine ZP glycoproteins, ZP4 contains the major potential sperm-binding sites, and the formation of a multivalent complex is necessary for the sperm-binding activity of ZP4.
Multimodal prediction of trait emotional intelligence–Through affective changes measured using non-contact based physiological measures
Authors: Prajapati Vrinda , Guha Rajlakshmi , Routray Aurobinda
Published: July 2021

Inability to efficiently deal with emotionally laden situations, often leads to poor interpersonal interactions. This adversely affects the individual’s psychological functioning. A higher trait emotional intelligence (EI) is not only associated with psychological wellbeing, educational attainment, and job-related success, but also with willingness to seek professional and non-professional help for personal-emotional problems, depression and suicidal ideation. Thus, it is important to identify low (EI) individuals who are more prone to mental health problems than their high EI counterparts, and give them the appropriate EI training, which will aid in preventing the onset of various mood related disorders. Since people may be unaware of their level of EI/emotional skills or may tend to fake responses in self-report questionnaires in high stake situations, a system that assesses EI using physiological measures can prove affective. We present a multimodal method for detecting the level of trait Emotional intelligence using non-contact based autonomic sensors. To our knowledge, this is the first work to predict emotional intelligence level from physiological/autonomic (cardiac and respiratory) response patterns to emotions. Trait EI of 50 users was measured using Schutte Self Report Emotional Intelligence Test (SSEIT) along with their cardiovascular and respiratory data, which was recorded using FMCW radar sensor both at baseline and while viewing affective movie clips. We first examine relationships between users’ Trait EI scores and autonomic response and reactivity to the clips. Our analysis suggests a significant relationship between EI and autonomic response and reactivity. We finally attempt binary EI level detection using linear SVM. We also attempt to classify each sub factor of EI, namely–perception of emotion, managing own emotions, managing other’s emotions, and utilization of emotions. The proposed method achieves an EI classification accuracy of 84%, while accuracies ranging from 58 to 76% is achieved for recognition of the sub factors. This is the first step towards identifying EI of an individual purely through physiological responses. Limitation and future directions are discussed.
Morphological and genetic diversity of traditional varieties of agave in Hidalgo State, Mexico
Authors: Figueredo-Urbina Carmen Julia , Álvarez-Ríos Gonzalo D. , García-Montes Mario Adolfo , Octavio-Aguilar Pablo
Published: July 2021

The agaves are plants of cultural importance which have been used by humans for about 10,000 years and about 40 specific uses. The most culturally and economically important of those uses are for the production of fermented (pulque) and distilled beverages (mescal). Pulque continues to be produced in nearly all of Mexico, and the agaves used for this purpose have shown domestication syndrome. We carry out an ethnobotanical, morphological, and genetic analysis of the traditional varieties of pulque agave used in the production ofaguamiel(agave sap) and pulque in the state of Hidalgo. We did semi-structured interviews, free listings, and tours with 11 agave managers. We analyzed morphology and studied genetic diversity and structure using nuclear microsatellites. We found wild-collected, tolerated, transplanted, and cultivated varieties of agave. This comprised 19 traditional varieties of pulque agave, 12 of them in production during the study, which corresponded to the speciesAgave americana,A.salmianayA.mapisagaand five intraspecific entities. The varieties were grouped morphologically according to a management gradient; the wild-collected varieties were the smallest, with more lateral teeth and a larger terminal spine. The cultivated varieties clearly exhibited domestication syndrome, with larger plants and smaller dentition. The expected heterozygosity (He) of the varieties ranged from 0.204 to 0.721. Bayesian clustering suggested the existence of three genetic groups, both at the level of traditional varieties of pulque agaves and for management categories, a result that matches multivariate clustering. Pulque producers in the studied localities maintain high agrobiodiversity. The cultivated varieties exhibit domestication syndrome, as has been reported for other species of the genus with the same selection purposes. Our results support the hypothesis of a decrease in genetic diversity in crops compared to wild-growing agaves, which seems to be due to vegetative propagation, among other factors.
General Practitioners as partners for a shared management of chronic HIV infection: An insight into the perspectives of Italian People Living with HIV
Authors: Bruno Serena Rita , Poliseno Mariacristina , Vichi Francesca , Esperti Sara , Di Biagio Antonio , Berruti Marco , Ferrara Sergio , Pisani Luigi , Saracino Annalisa , Santantonio Teresa Antonia , Lo Caputo Sergio
Published: July 2021

Is it possible to achieve a collaboration between Infectious Diseases (ID) Specialists and General Practitioners (GPs) in the management of chronic HIV infection? A cross sectional survey was conducted among People Living with HIV (PLWHIV) attending the outpatient services of four Italian Infectious Diseases Centers to understand to which extent patients trust their GPs and involve them in the management of their chronic condition. Information about level of communication with GPs, subjective perception of the disease, and presence of co-medications were collected and matched with socio-demographic data using χ2statistics. A p<0.05 was considered statistically significant. From December 2019 to February 2020, 672 patients completed the survey, 59% males and 56% >50 years. Overall, 508 patients (76%) had informed GPs about HIV-positivity. Communication of diagnosis was significantly associated with age >50years, lower education level, history of disease >10 years and residency in Northern Italy. The “Undetectable = Untrasmittable” (U = U) concept was investigated as an indirect measure of perceived stigma. 23% of subjects was unaware of its meaning. Despite undetectable status, 50% of PLWHIV found difficult to communicate their condition to GPs, especially married (52% vs 48% of unmarried, p = 0.003), well-educated patients (51% vs 48, p = 0.007), living in Southern vs Northern Italy (52% vs 46%, p< 0.001). More than 75% of the participants consulted the ID specialist for co-medications and DDIs management, often complaining a lack of communication of the former with GPs. Overall, a good level of communication between PLWHIV and GPs was outlined, even if a wider involvement of the latter in HIV care is desirable.
QTL mapping of seedling tolerance to exposure to low temperature in the maize IBM RIL population
Authors: Goering Raeann , Larsen Siri , Tan Jia , Whelan James , Makarevitch Irina
Published: July 2021

Maize is a cold sensitive crop that exhibits severe retardation of growth and development when exposed to cold spells during and right after germination, including the slowdown in development of new leaves and in formation of the photosynthetic apparatus. Improving cold tolerance in maize would allow early sowing to improve crop yield by prolonging a growing season and by decreasing the negative effects of summer drought, diseases, and pests. Two maize inbreds widely incorporated into American maize germplasm, B73 and Mo17, exhibit different levels of tolerance to low temperature exposure at seedling stage. In addition, thirty seven diverse inbred maize lines showed large variation for seedling response to low temperature exposure with lines with extremely low tolerance to seedling exposure to low temperatures falling into stiff stalk, non-stiff stalk, and tropical clades. We employed the maize intermated B73×Mo17 (IBM) recombinant inbred line population (IBM Syn4 RIL) to investigate the genetic architecture of cold stress tolerance at a young seedling stage and to identify quantitative trait loci (QTLs) controlling this variation. A panel of 97 recombinant inbred lines of IBM Syn4 were used to measure, and score based on several traits related to chlorophyll concentration, leaf color, and tissue damage. Our analysis resulted in detection of two QTLs with high additive impact, one on chromosome 1 (bin 1.02) and second on chromosome 5 (bin 5.05). Further investigation of the QTL regions using gene expression data provided a list of the candidate genes likely contributing to the variation in cold stress response. Among the genes located within QTL regions identified in this study and differentially expressed in response to low temperature exposure are the genes with putative functions related to auxin and gibberellin response, as well as general abiotic stress response, and genes coding for proteins with broad regulatory functions.
Using Assessment Design Decision Framework in understanding the impact of rapid transition to remote education on student assessment in health-related colleges: A qualitative study
Authors: Jaam Myriam , Nazar Zachariah , Rainkie Daniel C. , Hassan Diana Alsayed , Hussain Farhat Naz , Kassab Salah Eldin , Agouni Abdelali
Published: July 2021

Maintaining integrity and validity with online assessment is a significant issue that is well documented. Overt policies encouraging educators to adopt e-Learning and implement digital services coupled with the dramatic change in the education system in response to the challenges posed by COVID-19, has furthered the demand for evidence-based approaches for the planning and delivery of assessments. This study employed the Assessment Design Decision Framework (ADDF), a theoretical model that considers key aspects of assessment design, to retrospectively investigate from a multi-stakeholder perspective the assessments implemented following the rapid transition to remote learning during the COVID-19 pandemic. One-to-one semi-structured interviews were conducted with faculty and students from the Colleges of Pharmacy, Medicine and Health Sciences. After inductive and deductive thematic analysis three major themes were identified. These reflected on the impact of sudden transition on assessment design and assessment plan; changing assessment environment; and faculty-student assessment related interactions which included feedback. The use of a comprehensive validated framework such as ADDF, to plan assessments can improve validity and credibility of assessments. The strengths of this study lie in the innovative adoption of the ADDF to evaluate assessment design decisions from both an educator and student perspective. Further, the data yielded from this study offers novel validation of the use of ADDF in circumstances necessitating rapid transition, and additionally identifies a need for greater emphasis to be attributed to the significance of timeliness of the various activities that are advocated within the framework.
Resting heart rate is associated with colorectal advanced adenoma
Authors: Park Jihye , Han Jong Soo , Jo Hyun Jin , Kim Hyun Young , Yoon Hyuk , Shin Cheol Min , Park Young Soo , Kim Nayoung , Lee Dong Ho
Published: July 2021

Background and aims

Resting heart rate is an independent predictor of colorectal cancer (CRC) development and CRC-related mortality. However, little is known about the relationship between resting heart rate and colorectal adenoma development. We aimed to investigate this association in a population who underwent screening colonoscopy.

Methods

Among 39,021 patients who underwent both electrocardiogram and screening colonoscopy during routine health examinations at the Seoul National University Bundang Hospital, Health Promotion Center, Korea from January 2014 to July 2019, 1,344 patients had advanced adenoma. We performed 1:1 propensity score (PS) matching to establish a control group that mitigated the confounding effects of age and sex. We performed multivariate logistic regression analyses to identify the independent risk factors of advanced adenoma development.

Results

Resting heart rate was significantly higher in the advanced adenoma group than in the control group. The prevalence of advanced polyp increased across the quartiles of resting heart rate. Patients with higher resting heart rates were more likely to be older, smokers, and have increased blood pressure and DM and less likely to engage in active exercises than those with lower resting heart rates. Patients with higher resting heart rates had higher serum glucose, triglyceride, hemoglobin A1C, and insulin levels and lower high-density lipoprotein cholesterol levels. Patients with resting heart rate in the highest quartile (≥71 bpm) still showed significantly increased odds ratio (OR) of advanced adenoma development (OR: 1.379, 95% confidence interval: 1.099–1.731, p = 0.006).

Conclusions

High resting heart rate was a meaningful independent risk factor of advanced adenoma development.
Lengua y cultura persas para principiantes
Authors: Barani Nazia
Published: July 2021

La obra Lengua y cultura persas para principiantes parte del conocimiento del alfabeto persa y de su sistema de escritura por parte del alumno para conducirle hasta el aprendizaje de la lengua persa. La adquisición de vocabulario, así como la enseñanza de la gramática esencial son otras de las bases sobre las que se asienta el libro. Junto con los contenidos teóricos esta obra alterna, además, una serie de ejercicios para que los alumnos vayan constantemente poniendo en práctica lo que se les va enseñando. Por último, los aspectos socioculturales, religiosos, históricos, gastronómicos, literarios y turísticos de Irán se entremezclan también con el aprendizaje de la lengua con el fin de que los alumnos logren adquirir unos conocimientos básicos y generales de la cultura persa.
Los modelos de conocimiento como agentes de aprendizaje significativo y de creación de conocimiento
Authors: González García Fermín María , Veloz Ortiz Jorge Fernando , Rodríguez Moreno Iovanna Alejandra , Velos Ortiz Luis Efrén , Guardián Soto Beatriz , Ballester Valori Antoni
Published: July 2021

El cambio educativo que propugna el contexto actual exige un desplazamiento del modelo conductista - positivista desgraciadamente predominante,   que favorece el aprendizaje memorístico - mecánico, caldo de cultivo ideal para la existencia y mantenimiento de los errores conceptuales; a otro cognitivo - constructivista que estimule el aprendizaje significativo para permitir al alumno construir y dominar el conocimiento, por tanto ser más creativo y crítico. Aquí se presenta un modelo de conocimiento donde el alumno construye nuevo conocimiento como consecuencia de aprender significativamente. Los alumnos desempeñan un papel activo aprendiendo no solo acerca del producto sino del proceso mismo (metaconocimiento). También mostramos como promover la actividad del profesor fundamentalmente para crear las condiciones que faciliten la transformación a cargo del alumno de información en conocimiento útil, sustantivo, que se integre en su estructura  de conocimiento en la memoria a largo plazo. Por último se proporcionan elementos para medir lo que el alumno sabe y valorar cómo ha cambiado su estructura cognitiva en relación con antiguos conocimientos, esto es evaluar el necesario cambio conceptual.
La planificación estratégica, un indicador sobre el liderazgo pedagógico
Authors: Martín Manzano Joaquín , Mominó De La Iglesia Josep Maria , Carrere Balcells Juli
Published: July 2021

Destacando la función del liderazgo pedagógico como factor decisivo para la eficacia en el funcionamiento de los centros educativos, este  artículo analiza la planificación estratégica como indicio de la presencia de dicho factor crítico en la dinámica de las escuelas e institutos españoles. En el análisis de las variables asociadas al nivel de desarrollo de este tipo de actividad directiva, se pone de manifiesto su vinculación con el liderazgo para el aprendizaje  al que se concede una mayor potencialidad por su contribución al éxito educativo. El estudio de los indicios disponibles sobre el nivel de desarrollo alcanzado por esta forma de acción estratégica pone de manifiesto su vinculación a las creencias de los directores más que a las condiciones que establece el contexto en que se circunscribe la actividad de las escuelas. Los resultados se han obtenido de una muestra de 694 directores, representativos de los centros educativos españoles en sus etapas obligatorias.
Wiris Quizzes: un sistema de evaluación continua con feedback automático para el aprendizaje de matemáticas en línea
Authors: Calm Remei , Masià Ramon , Olivé Carme , Parés Núria , Pozo Francesc , Ripoll Jordi , Sancho-Vinuesa Teresa
Published: July 2021

En estudios en línea de ingeniería, el seguimiento del proceso de aprendizaje de los estudiantes de matemáticas así como el sistema de evaluación son aspectos clave de la estrategia docente. En este artículo se presenta un sistema de evaluación continua con feedback automático, basado en la realización de cuestionarios Wiris Quizzes durante un curso de análisis matemático en la Universitat Oberta de Catalunya. Dichos cuestionarios, con enunciados parametrizados, funcionan en el entorno de Moodle con el soporte del programa de cálculo simbólico Wiris (www.wiris.com). Los resultados de la experiencia docente con esta metodología en una aula con 65 estudiantes y la comparación con los de semestres anteriores son claramente positivos: (a) el número de estudiantes que siguen la evaluación continua se mantiene estable; (b) la media de las notas de la evaluación continua aumenta de forma considerable; (c) el número de estudiantes que suspenden la asignatura se ha reducido significativamente y (d) la valoración que los estudiantes hacen de la asignatura, de sus contenidos y de los recursos que se ponen a su disposición ha mejorado notablemente.
Editorial: Aspectos pedagógicos en la Informática Educativa
Authors: García Peñalvo Francisco José , Vicent Safont Lluís
Published: July 2021

La tecnología aplicada a los procesos de enseñanza/aprendizaje es una realidad en una sociedad que se encamina a una Sociedad del Conocimiento. El diseño de los constructos tecnológicos con aplicación en dichos procesos es el objeto de la Informática Educativa como disciplina. Sin embargo, cuando este diseño se realiza sin los adecuados objetivos pedagógicos, o cuando, de forma más crítica porque puede haber productos tecnológicos de perfil generalista que se usan posteriormente con fines educativos, el uso de una tecnología en un contexto educativo se hace de espaldas a criterios pedagógicos o el diseño instruccional de la acción formativa no integra bien esa tecnología, el fin último, EL APRENDIZAJE, puede quedar seriamente comprometido. Esto tiene una clara implicación en que los avances en Informática Educativa requieren, en la mayor parte de los proyectos, de equipos interdisciplinares donde, a parte de otros roles, los perfiles tecnológicos y pedagógicos estén bien cubiertos. Ejemplo de esta relación sinérgica y simbiótica se da en el Simposio Internacional de Informática Educativa, SIIE, que tras 14 ediciones se ha convertido en uno de los foros que mejor muestra este principio. En este número especial de la revista TESI se han seleccionado seis trabajos presentados en la pasada edición del SIIE, celebrada en Andorra a finales de octubre de 2012, en los que sobresale esta vinculación entre Tecnología y Educación.
Indagando en la relevancia de Internet en el acceso, uso y deseos de las TIC por parte de las mujeres en las TIC
Authors: Vergés Bosch Núria , Hache Alex , Cruells Lopez Eva
Published: July 2021

A partir de los años 90 las teorías feministas de la tecnología experimentan un optimismo renovado con la aparición de las TIC y el desarrollo de la tercera ola feminista. Sin embargo, la investigación en género y tecnología se ha centrado en estudiar la exclusión de las mujeres de las TIC e, inversamente, las experiencias de las mujeres y sus estrategias para incluirse en las TIC han recibido menos atención. Motivadas por nuestras experiencias tecnoactivistas y la observación de una remarcable presencia de mujeres en ellas, con Donestech, iniciamos un proyecto de investigación sobre los accesos, usos y deseos de las mujeres en las TIC. A través de una investigación ciberfeminista recogimos, analizamos y visibilizamos las experiencias y opiniones de las mujeres en las TIC. Nuestros resultados sugieren que las trayectorias de inclusión y acceso de las mujeres en las TIC son diversas, así como heterogéneos son los usos que hacen de ellas, destacando el rol jugado por Internet en todo ello. Además mostramos que las mujeres en las TIC son curiosas y entusiastas, que quieren empoderarse y compartir el conocimiento. Finalmente, les disgusta y desconfían de las relaciones de poder existentes en los mundos tecnológicos, manteniendo una actitud crítica y creativa hacia las TIC.
Estrategias de aprendizaje en estudiantes universitarios. diferencias por género, curso y tipo de titulación
Authors: López Aguado Mercedes
Published: July 2021

La investigación sobre el efecto del género, el curso o la titulación sobre las estrategias de aprendizaje no es concluyente. Resulta necesario profundizar en la forma en que estas variables están relacionadas, especialmente con análisis de corte multivariado. Se realiza una investigación de corte no experimental en la que participan 805 estudiantes universitarios. Se recoge la información con el Cuestionario de Estrategias de Trabajo Autónomo (CETA). Los resultados indican que las tres variables analizadas tienen efecto individual sobre las estrategias de aprendizaje, aunque el curso resulta el peor predictor. Del análisis de resultados se desprende la necesidad de considerar los efectos combinados que matizan, y en ocasiones contradicen, los efectos simples de las variables. El conocimiento de las estrategias por estos grupos de interés permitirá a los docentes ajustar la formación de manera específica a las diferentes formas de aprender de sus alumnos.
Una perspectiva histórica de la educación bilingüe en Estados Unidos
Authors: García Garrido Mª Isabel , Fernández Álvarez Miguel
Published: July 2021

El presente artículo presenta una revisión de la evolución de la educación bilingüe en los Estados Unidos. Así pues, presentamos una sinopsis de los principales movimientos que han estado en contra y a favor del bilingüismo.  El respeto por la diversidad cultural y lingüística empezó a verse comprometido a partir de 1750 cuando Benjamín Franklin llevó a cabo el primer intento de imponer el inglés como el lenguaje oficial de los Estados Unidos. La oposición más fuerte al bilingüismo vio la luz en 1983 a través de un movimiento conocido como U.S. English. En 1986 aparecería otro movimiento con las mismas intenciones que U.S. English, el llamado English First. No obstante, el bilingüismo también ha tenido sus defensores, tales como el movimiento llamado English Plus. A su vez, el futuro del bilingüismo también se ha visto protegido de forma legal a través de tres actas gubernamentales: (1) Elementary and Secondary Education Act (ESEA), (2) Bilingual Education Act of 1968, y (3) No Child Left Behind Act.
Los neologismos en la sociedad de la información: análisis de su presencia y ausencia en las fuentes lexicográficas escolares
Authors: Prat Sabater Marta , Sierra Infante Sonia
Published: July 2021

En la actual Sociedad de la Información, el flujo de palabras entre distintos países así como la creación de neologismos es constante y los más jóvenes se muestran, en general, más permeables a su adquisición. Factores como la emigración y la popularización de Internet y de las redes sociales han traído al español nuevos vocablos que se incorporan, sobre todo, en la lengua oral. Por ello, hemos querido comprobar qué grado de aceptación tienen en las obras lexicográficas diferentes términos de uso frecuente entre los escolares. En este trabajo se ha seleccionado un corpus de cuarenta palabras, agrupadas según sean dialectalismos, coloquialismos o extranjerismos, y se ha analizado su presencia o ausencia en diferentes diccionarios escolares de primaria y secundaria y en fuentes académicas. También se han estudiado las marcas que señalan el registro al que pertenecen y las pautas de ortografía y pronunciación de los extranjerismos. Para escoger los diferentes términos, hemos basado nuestra búsqueda en varios perfiles de Facebook de estudiantes de secundaria y en revistas en línea como Superpop.
Motivaciones y satisfaciones generizadas en el digital_learning: un estudio de caso
Authors: Quattrocchi Stefania , Biglia Barbara , Naldini Masssimiliano , Colicino Silvia
Published: July 2021

En este articulo presentamos un análisis diferencial de género, en relación a una muestra de docentes de matemática de la escuela publica italiana que han participado, en el año académico 2009/10 a una formación blended (mixta) erogada por el Agencia Nacional Por el Desarrollo de la Autonomía Escolar, focalizada en las motivaciones en participar y en la satisfacción que provocan. En las sociedades (post)industrializadas la brecha digital de género ya no es básicamente un problema cuantitativo sino se relaciona directamente con las modalidades de uso de las TIC y la satisfacción que este uso conlleva, aspectos desafortunadamente aun poco explorado en las investigaciones académicas, al que queremos contribuir con nuestro análisis. Los resultados de nuestro estudio, coherentemente con las evidencias de otros trabajos, muestran generizaciones en el acercamiento a los cursos blenden que demuestran la necesidad de diseñar espacios y actividades formativas desde una perspectiva menos androcéntrica, más atractiva e inclusiva. Los resultados obtenidos hacen además patente la urgencia de continuar a investigar en este ámbito estratégico para superar de la brecha digital cualitativa de género.
Aprendizaje cooperativo y heurístico en la red internacional e-Culturas
Authors: Pantoja Vallejo Antonio , Blanco López Eladio
Published: July 2021

Los entornos virtuales de aprendizaje, convertidos en plataformas digitales, favorecen la colaboración y la interacción entre usuarios, al mismo tiempo que permiten que la capacidad creativa se vea incrementada considerablemente. Sobre estas premisas se fundamenta el Programa Intercultural e-Culturas que se pone en marcha a través de la Red Internacional e-Culturas (http://www.e-culturas.org). Se trata de un proyecto colaborativo en red que tiene como fin hermanar a niños de diferentes nacionalidades para trabajar una serie de materiales interculturales. En la presente comunicación se exponen las líneas metodológicas básicas que sustentan el mismo.
Experiencias docentes de trabajo colaborativo en distintas áreas de ciencias
Authors: Prieto Calvo Cristina , Rodríguez Puebla Concepción , Hernández Encina Ascensión , Queiruga Dios Araceli
Published: July 2021

Se comparan los resultados de las experiencias docentes colaborativas desarrolladas en asignaturas de diferentes ramas de ciencia. El planteamiento inicial es común: involucrar de forma activa al estudiante en su proceso de aprendizaje. La metodología del trabajo en colaboración fue particularizada según los objetivos de cada asignatura y el nivel de los estudiantes. Como resultado del trabajo se destaca la respuesta favorable y la mayor participación de los estudiantes mediante la incorporación de actividades de estudio colaborativo.
Ensanchando los límites: Una aproximación desde la didáctica a la traducción literaria / Enlarging the limits: A didactic approach to literary translation
Authors: Fortea  Gil Carlos , Santana  López Belén
Published: July 2021

La problemática fundamental de la traducción literaria ronda siempre en torno a su propia posibilidad, los límites y metas de la reflexión sobre ella y la capacidad de trasladar esa reflexión a la práctica. En este contexto, ha sido metodológicamente frecuente partir del texto meta, tratando de extraer premisas, métodos y procedimientos. Nuestro planteamiento inicial pretende ser el inverso: partir de la traducción misma, en su vertiente aplicada a la didáctica, para extraer del proceso traductor tutelado posibles conclusiones sobre la esencia del proceso y su generalización para la práctica. La finalidad sería extraer principios teóricos a partir de principios prácticos, reflexiones al hilo de dificultades recurrentes, apuntes sobre posibles marcas textuales que apuntan a formatos de resolución de problemas (calidad de los textos originales, concepto de fidelidad, tono, etc., entendidos siempre desde el punto de vista de lo verificable o señalable en concreto en los textos). El modesto objetivo de este artículo es llamar la atención con ejemplos sobre la peculiaridad de la didáctica de la traducción literaria como posible método de indagación en la traducción literaria misma.  The basic problem of literary translation lies in its very possibilities, in the limits and aims of all reflection on it, and in the capacity to shift this reflection to practice. In this context, the methodological starting point is normally the target text, from which premises, methods and procedures are extracted. In this paper, however, our aim is to take translation itself, as applied to didactics, as our starting point in order to extract from the supervised translating process possible conclusions regarding the essence of the process and its generalization for practice. The final aim is to extract theoretical principles based on practical principles, reflections on recurring difficulties, information about possible textual markers pointing to problem-solving formats (source text quality, loyalty concept, tone, etc., which are always understood from the point of view of what can be verified or pointed out specifically in texts). This paper aims, through examples, to draw attention to the peculiarity of literary translation didactics as a possible research method into literary translation.