bluuebunny/crossref_metadata_2025 huggingface dataset:
O direito de colher, o direito de filmar em “Agahü
Authors: Alvernaz Sabrina
Published: July 2023

Este artigo se debruça sobre o curta-metragem Agahü: o sal do Xingu (2020) do cineasta indígena Takumã Kuikuro e seu contexto de produção na Terra Indígena do Xingu, Mato Grosso, Brasil. O documentário dialoga com a Declaração Universal dos Direitos Humanos, mais especificamente com o direito à liberdade de pensamento, consciência e religião, de maneira a enfatizar que o “sal tradicional” conjuga ciência, arte, fé. Especial destaque é dado à dinâmica de produção imagética, considerando desdobramentos audiovisuais e político-sociais a partir da elaboração do roteiro, de escolhas de tradução e montagem. O foco também recai sobre a relação que a sociedade kuikuro tem com o sal tradicional. A resistência, a partir da insistência por um modo de vida Kuikuro, é entendida pelo viés da sustentabilidade ambiental diante da defesa do direito de colher seu alimento.
"Se eu pensava, eu existia"
Authors: Zanfelice Gabriela Beduschi , Gallo Fernanda Bianca Gonçalves
Published: July 2023

O enredo de Memórias de porco-espinho consiste em confissões feitas por um porco-espinho a um baobá sobre sua vida e os crimes que cometeu em nome de seu mestre humano Kibandí. Anunciando abertamente sua animalidade, o porco-espinho ironiza os padrões classificatórios e generalistas dos humanos, mobilizando uma série de elementos que colocam em xeque certos binarismos como natureza e cultura, seres animados e seres inanimados, e questionam a inadequação dessas classificações frente à diversidade e à complexidade animal. Neste artigo, busca-se analisar os modos através dos quais essa autobiografia animal convoca a repensarmos conceitos como humano e não-humano, a categorização em gêneros literários específicos e bem delimitados, os paradigmas dominantes da ciência e as relações entre ficção e realidade, com implicações significativas para examinarmos as relações entre humanos e animais.
Algumas figurações da catástrofe ancestral na América Latina
Authors: Ruggieri Mariana
Published: July 2023

Partindo da ideia da “catástrofe ancestral” – colonial e racial – em oposição à “catástrofe por vir”, o texto se debruça, ao modo de fragmentos, sobre A queda do céu, de Davi Kopenawa e Bruce Albert (2015), Primera nueva corónica y buen gobierno, de Waman Puma de Ayala (1615), “Chiapas: el sureste en dos vientos, una tormenta y una profecia”, do Ejército Zapatista de Liberación Nacional (EZLN, 1994), uma filmagem do enterro de Emiliano Zapata (1919) e Torto arado, de Itamar Vieira Junior (2019). Por meio desses e outros textos, o intuito é qualificar o anthropos do antropoceno.
Literatura e meio ambiente
Authors: Augusto Cá Ianes
Published: July 2023

O uso inconsciente dos recursos naturais está levando o mundo à beira do abismo, com a crescente destruição das florestas naturais; a diminuição drástica das reservas de combustível fóssil; a contaminação do meio ambiente; as alterações climáticas e os desastres ambientais que já estão acontecendo e atormentam o mundo, ameaçando sobrevivência das espécies e – consequentemente, causando a destruição do ecossistema e da possibilidade de modos sustentáveis de relação do homem com a natureza. Partindo dessa constatação, a ecocrítica se constitui como movimento mundial emergente contra atitude antropocêntrica em relação à natureza, potencializada pela ascensão capitalista. Nesse contexto, este estudo tem como propósito rastrear os debates em torno da literatura e do meio ambiente nas literaturas africanas, e como a consciência ecológica aparece nos textos literários dos seus escritores. De modo específico, busca-se compreender como a ecopoética (Terra-poesia) constitui um elemento estruturante do eu-poético nos dois poemas intitulados “Voltar ao poilão”, I e II, da obra Desesperança no chão de medo e dor, de Tony Tcheka (2015) – nos quais se manifestam a experiência e o entrelaçamento entre os humanos e os não-humanos, considerando que floresta, fauna e flora – o “mundo natural” – se constituem como uma ampla rede de inter-relações intrínsecas à própria existência humana. A reflexão parte de uma perspectiva interdisciplinar, por meio da abordagem dos estudos da ecocrítica e dos estudos pós-coloniais como posicionamento político e ético, pautados nas relações econômicas, culturais e ecológicas que problematizam as práticas hegemônicas e as novas formas de domínio de subalternização e de exploração.
Dificuldade da poesia
Authors: Lopes João Gabriel Mostazo
Published: July 2023

Este artigo procura desenhar os primeiros parâmetros do que, no decorrer desta pesquisa em curso, estamos chamando de “dificuldade da poesia”. Para isso, toma-se como ponto de partida a reflexão crítica sobre o conceito de “resistência” formulado por Alfredo Bosi nos anos 1970. Busca-se demonstrar que o funcionamento do conceito bosiano de resistência depende de uma dupla projeção: de um lado, tendo perdido a sua capacidade de “nomear a vida”, o poema resistente, ou lido sob a chave da “poesia enquanto resistência”, projeta-se sobre a imagem do que o autor chama de “unidade mítica perdida” da poesia; de outro, instalando-se em um “presente aberto”, o poema resistente profetiza um “futuro promissor”. A partir de uma análise da conjuntura política e ideológica do Brasil de hoje e, de modo mais amplo, do capitalismo contemporâneo, este artigo recorre às obras de três poetas brasileiros contemporâneos para defender a hipótese de que este mecanismo de dupla projeção já não encontra lugar hoje, razão que nos leva a procurar definir os impasses da poesia contemporânea a partir não da ideia de “resistência”, mas da proposição do conceito de “dificuldade”, cujas delimitações teóricas esta pesquisa tem por objetivo estabelecer.
Para além do humano
Authors: Banasiak Marta
Published: July 2023

Partindo dos estudos de museologia e da teoria da ecocrítica da matéria vinda diretamente da perspetiva do novo materialismo, propõe-se uma leitura do mais recente romance de João Paulo Borges Coelho Museu da Revolução (2021). O estudo observa o processo de  transformação da narrativa em uma exposição interativa, ou exposição em movimento, explorando as capacidades narrativas dos elementos  não-humanos e, ao mesmo tempo o processo de  limitação da agência do elemento humano (personagens) e sua transformação em objetos malháveis. Assume-se que essa construção de discurso participa no projeto de recuperação da(s) histórias(s) da revolução moçambicana, as suas origens políticas e históricas e as suas consequências na contemporaneidade igualmente como a colocação do país dentro do contexto da geopolítica mundial.
O Lienzo, a Conquista e as mulheres
Authors: Theodoro Gabriela
Published: July 2023

Este artigo analisa a presença (e ausência) das representações femininas no códice Lienzo de Tlaxcala em sua narrativa visual da Conquista de México-Tenochtitlán. Para isso, selecionou-se algumas lâminas do documento, a fim de analisar a maneira como as mulheres foram retratadas e como esse silêncio a respeito do feminino aponta para o enfoque dado pela historiografia, e não para um vazio documental, tampouco para uma ausência no processo histórico. Assim, este artigo buscará contribuir na escrita de uma narrativa mais plural e que leve em conta a diversidade étnica, política, social e de gênero presente durante esse processo
Smart cities - spatial planning and disaster risk reduction of Pune city, India
Authors: Kodag Sujata , Kodag Abhishek
Published: July 2023

Cities are becoming the preferred choice of populations to reside in due to the opportunities they offer. While the concentration of populations is increasing in the cities, there is an immediate need to equip the cities for efficient functioning and providing safety and security. The unplanned urbanization of cities is adding vulnerability, especially to the spatially relevant hazards such as earthquakes and floods. Initiatives such as the Smart City Mission support cities with investments to improve the quality of life for people and enhance the efficiency of the civic systems by integrating infrastructure and technology. However, the top down approach to decision making, especially in spatial planning, leaves out the perspective of citizens. This study, hence, attempts to gather the perception of citizens on smart city initiatives and disaster risk reduction (DRR) through a questionnaire survey in the smart city of Pune, India. The objective of this study is to understand how smart city initiatives influence the key spatial planning components for DRR. The study reveals smart city initiatives proposed for the city impacts each spatial planning component. Smart city initiatives may further stress these components, increasing the exposure to disaster risks. Therefore, there is a need for holistic integration in spatial planning for DRR. This study can help in modulating the smart city initiatives for enhancing the safety of the citizens.
Fatigue detection using decision tree method based on PPG signal
Authors: Zaeni Ilham Ari Elbaith , Wardhana Arya Kusuma , Fanani Erianto
Published: July 2023

Fatigue is a complex psychophysiological condition marked by sleepiness or fatigue, poor performance, and a range of physiological changes. A decision tree may be used to categorize weariness based on the subject's heart rate data. To begin the experiment, a dataset of the heart rate signal was obtained. The signal has already undergone preprocessing. The feature obtained through preprocessing is then used to construct the decision model. Four traits were discovered. The HF power, LF power, normalized HF power, and normalized LF power are the characteristics. This research has a 75.94% accuracy rating. The precision, recall, and F-measure scores for this study were 0.736, 0.736, and 0.736, respectively.
Genetic Origin Affects the Reduction of Fruit Load in Young Grapevines Sprayed with an Organosilicone Surfactant and Ethephon
Authors: Klein Joshua D. , Cohen Shlomo
Published: July 2023

Combinations of Dilwet, an organosilicone surfactant, and ethephon, a hormonal compound often applied to fruit trees to thin the crop, were applied at full bloom to prevent fruit development in two young vineyards differing in elevation by 600 m. Each vineyard was planted with the same 19 red and 10 white grape cultivars from a range of countries of origin. Vineyard elevation did not affect response to treatment. A combined spray of 0.5% Dilwet with 0.04% ethephon reduced cluster number by an average of 85%, while weight of the remaining clusters was reduced by 63%, compared to unsprayed controls. Increasing the concentration of Dilwet to 1% reduced cluster number by 93% and cluster weight by 76%. There were significant differences in the response of cultivars to the treatments, depending on country of origin, with grapes originating in France responding better to higher concentrations of Dilwet. White grapes were more responsive than red grapes. These results highlight the need to test different cultivars and genetic origins of crops when examining the effects of new agricultural chemicals.
Depression and Its Associated Factors Among Undergraduate Engineering Students: A Cross-Sectional Survey in Thailand
Authors: Huang Yuanyue , Wongpakaran Tinakon , Wongpakaran Nahathai , Bhatarasakoon Patraporn , Pichayapan Preda , Worland Shirley
Published: July 2023

Background: Depression is a common mental health problem that can affect everyone at different stages of development. Though the prevalence rate of depression among university students is rising, exploration among engineering students is limited. The aim of the study was to examine the prevalence of depression and its associated factors of among engineering students in Thailand. Methods: 346students participated in this study. All completed the outcome inventory-depression subscale (OI-D) to evaluate the level and prevalence of depression. Other variables assessed included social skill, learning styles, relationship satisfaction, interpersonal difficulty, alcohol use, internet addiction, and neuroticism. Correlation and regression analysis were applied to test the association between sociodemographic and psychosocial factors and depression. Results. Of 346 students with the mean age was 20.25 (SD, 1.33), 52.31% was male. Based on the OI-D, 35.3% of participants exhibited symptoms indicative of major depression. Multiple regression showed that only neuroticism, interpersonal difficulties, social skills, and self-esteem appeared to be the significant predictors of depression. Conclusion: the prevalence of depression among engineering students is unexpectedly high. Intra and interpersonal factors were found to be associated with depression. Further study on identifying these risk factors should be encouraged.
Performance Model and Research Practice of Youth Entrepreneurship Platform in the Context of Common Wealth Returning to Hometown
Authors: Liu Ailing , Ma Xiaojun , Zhou Meimei , Zeng Lichen , Lu Jijian Lu
Published: July 2023

In order to investigate the relationship between government policy, the service and design of rural crowdsourcing spaces, the self-efficacy of returning youth, and the innovation performance of businesses, this study focuses on gathering data by distributing questionnaires to returning youth in rural crowdsourcing spaces and developing a structural model. The results demonstrate how important government policies are in encouraging youth entrepreneurship in their local communities. It has the potential to enhance both the development of rural crowdsourcing spaces and the self-efficacy of young entrepreneurs, thereby enhancing the innovative capabilities of local entrepreneurial businesses. Therefore, in order to encourage economic development in rural areas, the government should improve pertinent support measures.
A Convolution-Based AI Neural Network Achieves 90% Accuracy in Predicting Cancer Type Based on Copy Number Alterations
Authors: Mickael Michel
Published: July 2023

The accurate identification of the primary tumor origin in metastatic cancer cases is crucial for guiding treatment decisions and improving patient outcomes. Copy Number Alterations (CNA) have emerged as valuable genomic markers for predicting the origin of metastases. This research article presents a comprehensive analysis of CNA-based prediction models in metastatic cancer. The study utilizes a dataset comprising CNA profiles from twenty different cancer types and employs advanced AI-based techniques for prediction. The research workflow consists of two models. The first is convolution network-based, while the other is a multi-stage model. In the first stage, a RELU model is developed to differentiate between 16 cancer types, considering their CNA, chromosome location, strand, and overall location. The second stage involves building specialized models to detect differences between cancer types within the same location or organs, such as brain lower-grade glioma and glioblastoma multiforme. Both generalized models achieve an overall accuracy of over 90%, while the specialized models achieve an accuracy of approximately 95% with minimal loss values. The results demonstrate the potential of AI-based approaches utilizing CNA data for improved diagnosis and personalized treatment strategies in metastatic cancer. This research establishes a solid foundation for future advancements in the field, paving the way for more effective and targeted approaches in metastatic cancer management.
Development of Commercial Eucalyptus Clone in Soil with Indaziflam Herbicide Residues
Authors: Maciel Josiane Costa , Duque Tayna Sousa , Carvalho Aline Cristina , Alencar Brenda Thais Barbalho , Ferreira Evander Alves , Zanuncio José Cola , Castro Bárbara Monteiro de Castro e , Da Silva Francisca Daniele , Silva Daniel Valadão , Santos José Barbosa dos
Published: July 2023

The pre-emergent herbicide indaziflam is efficient in the management of weeds in eucalyptus crops, but this plant may develop less in soil contaminated with it. The objective was to evaluate the levels of chlorophylls a and b, the apparent electron transport rate (ETR), growth and dry matter of leaves, stems and roots of Clone I144, in clayey soil, contaminated with the herbicide indaziflam and the leaching potential of this herbicide. The design was completely randomized in a 3 x 5 factorial scheme, with four replications. Chlorophyll a and b contents, apparent electron transport rate (ETR), height growth and dry matter of leaves, stems and roots of Clone I144 were evaluated. The leaching of indaziflam in the clayey soil profile (69% clay) was evaluated in a bioassay with Sorghum bicolor, a plant with high sensitivity to this herbicide. The visual intoxication and height of this plant were evaluated at 28 days after sowing (DAS). Chlorophyll a and b contents and ETR, height and stem dry matter of Clone I144 were lower in soil contaminated with indaziflam residues. The dose of indaziflam, necessary to cause 50% (C50) of intoxication and the lowest height of sorghum plants, was 4.65 and 1.71 g ha-1 and 0.40 and 0.27 g ha-1 in clayey soil and sand, respectively. The sorption ratio (SR) of this herbicide was 10.65 in clayey soil. The herbicide indaziflam leached up to 30 cm depth at doses of 37.5 and 75 g ha-1 and its residue in the soil reduced the levels of chlorophylls a and b, the apparent electron transport rate (ETR) and the growth of Clone I144.
Gravisensitivity Of Stromal Collagen Fibers In The Gastrointestinal Hollow Organs Of Mice After A 30-Day Space Flight
Authors: Shishkina Viktoriya , Kostin Andrey , Alexeeva Nataliya T , Klochkova Svetlana V , Nikityuk Dmitry B , Volodkin Artem , Buchwalow Igor , Tiemann Markus , Atiakshin Dmitri
Published: July 2023

The digestive organs are highly sensitive to the influence of orbital flight factors and can limit the professional activities of crew members aboard the International Space Station. Connective tissue as a system-forming matrix of the integrative-buffer metabolic environment is of particular relevance in space biomedicine, ensuring the functioning of internal organs under an altered gravitational stimulus. However, the adaptive mechanisms of the fibrous extracellular matrix of the gastric and intestinal connective tissue have not been fully investigated under prolonged microgravity weightlessness. Using histochemical techniques, the authors experimentally studied the state of collagen fibers in the specific tissue microenvironment of the gastric and intestinal membranes in C57BL/6N mice after a 30-day space flight, subsequent 7-day ground readaptation, and in animals of the relevant control groups. The 30-day stay of laboratory animals aboard the Bion-M 1 biosatellite resulted in a reduction in the fibrous extracellular matrix of connective tissue in the studied digestive organs, excepting the gastric lamina propria. An increased fibrillogenesis was revealed in the gastrointestinal mucous membranes of animals in 7 days after the biosatellite landing, if compared with the parameters of animals of the space flight group. During the experiment with ground simulated orbital flight conditions, changes in collagen fibers were not significant compared to the vivarium control group. Thus, the results obtained evidence gravisensitivity of the fibrous extracellular matrix of the intraorgan connective tissue. This fact also highlights the necessity to further improve gastrointestinal tract-related preventive measures for astronauts during orbital flight.
Structural Studies of Monounsaturated and ω-3 Polyunsaturated Free Fatty Acids in Solution with the Combined Use οf NMR and DFT calculations -Comparison with the Liquid State
Authors: Gerothanassis Ioannis P. , Siskos Michael G. , Papamokos Georgios , Venianakis Themistoklis
Published: July 2023

Molecular structures, in chloroform and DMSO solution, of the monounsaturated free fatty acids (FFAs) caproleic acid (dec-9-enoic acid) and oleic acid (octadec-9-enoic acid) and the ω-3 FFAs α-linolenic acid (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid ALA), eicosapentanoic acid (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid) and docosahexaenoic acid (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid), are reported with the combined use of NMR and DFT calculations. Variable temperature and concentration chemical shifts of the COOH protons and transient 1D NOE experiments, in CDCl3, demonstrate the major contribution of low molecular weight aggregates of dimerized fatty acids, through intermolecular hydrogen bond interactions of the carboxylic groups, with parallel and antiparallel interdigitated structures, even at the low concentration of 20 mM. For the dimeric DHA, a structural model of an intermolecular hydrogen bond through carboxylic groups and an intermolecular hydrogen bond between the carboxylic group of one molecule and the ω-3 double bond of a second molecule, is shown to play a role. In DMSO-d6 solution the centro-symmetric hydrogen bond interactions are broken and the carboxylic groups form strong intermolecular hydrogen bond interactions with a discrete solvation molecule of DMSO. These solvation species form parallel and antiparallel interdigitated structures of low molecular weight. DFT structural models in CHCl3 and DMSO, in agreement with the NMR data, are compared with the structures in the liquid state
The Kinetic and Energetic Pull of Chemical Entropy
Authors: Baker Josh
Published: July 2023

Proteins in biological systems function at the interface of single molecule and bulk chemistry and thus provide novel insights into the basic physical chemistry of scaling and emergent phenomena. For example, a binary mechanical model based on the chemistry of muscle contraction unifies molecular mechanics and thermodynamics and provides an explicit solution to the Gibbs paradox. Using the same model system, here I show that chemical activities of molecular states have no effect on chemical kinetics or energetics. Specifically, while the concentration or number of molecules in a molecular state is widely thought to contribute to reaction free energies, here I show that it is not the physical presence of molecules that pushes a reaction forward but the number of microstates, , accessible in a chemical state that pulls a reaction toward equilibrium with an entropic force down an entropic funnel. With the derivation of an entropic contribution to chemical kinetics, I develop a novel chemical kinetic formulation that fully describes the chemical thermodynamics of both equilibrium and non-equilibrium reactions in terms of an a priori system reaction energy landscape.
Skin Lesion Synthesis and Classification Using an Improved DCGAN Classifier
Authors: Behara Kavita , Bhero Ernest , Agee John Terhile
Published: July 2023

Keywords: Convolutional Neural Network, Deep Learning, Skin cancer, Generative Adversarial Network
Exploration into Natural Variation for Genes Associated with Determinate and Capitulum-like Inflorescence in Brassica napus
Authors: Wan Wei , Zhao Haifei , Yu Kunjiang , Xiang Yang , Dai Wendong , Du Caifu , Tian Entang
Published: July 2023

Brassica napus is an important vegetable and oil crop worldwide. The research is meaningful for yield and plant architecture in B. napus. In this study, one natural mutant (MT) line with determinate and capitulum-like inflorescence was chosen for further study. The paraffin sectioning detected that the inflorescence apex began to split and developed into one terminal flower, starting from five-leaf stage. Genetic analysis indicated that the segregation patterns of inflorescences in the F2 populations supported a digenic inheritance model, which was further approved by BSA-Seq technique. The BSA-Seq method detected two QTL region on C02 (14.27-18.41 Mb) and C06 (32.98-33.68 Mb) for the genetic control of determinate inflorescences in MT plants. In addition, the expression profile in MT compared with WT was analysized, and a total of 133 candidate genes for regulating the flower development (75 genes, 56.4%), shoot meristem development (29 genes, 21.8%) and inflorescence meristem development (13 genes, 9.8%) were identified. Then one joint analysis combing BSA-Seq and RNA-Seq identified two candidate gene of BncTFL1 and BncAP1 for regulating the MT phenotype. Besides, the potential utilization of the MT plants was also discussed.
Erosion Behaviour of Co-28Cr and WC-12Co Coatings on SA213-T22 Boiler Steel
Authors: Kiatisereekul Aumpava , Siripongsakul Thamrongsin , Fakpan Kittichai
Published: July 2023

At Mae-Moh power plant, Thailand, superheater tubes, which are exposed in fly ash environ-ment, often degrade due to solid particle erosion. To extend the service lifetime of the superheater tubes, the high velocity oxy-fuel (HVOF) thermal spray technique is used to deposit a protective coating on the material, SA213-T22 steel. In this work, the solid particle erosion of the Co-28Cr and WC-12Co coatings was investigated using erodent particle impingement at the angles of 30o and 90o with an average particle size of 60 μm. The erosion behavior of SA213-T22 with and without Co-28Cr and WC-12Co coatings was explained using ductile and brittle erosion modes. The erosion test resulted in the brittle mode for both Co-28Cr and WC-12Co coatings, while SA213-T22 without coating indicated the ductile mode. On the investigation of surface morphology, the Co-28Cr coating showed mostly microcracks in contrast with the WC-12Co coating, fracture, de-bonding and deep cavities were also observed. Erosion resistance of the Co-28Cr coating was significantly higher than the WC-12Co coating, due to high hardness, low porosity and high density of the coating.
The Largest Historical Stranding of Physalia physalis Recorded
Authors: Torres Conde Eduardo Gabriel , Rodríguez Martínez Rosa Elisa
Published: July 2023

Historically, Physalis physalis massive stranding events have been infrequent and poorly documented. However, their occurrence can have significant impacts on human health and the stability of coastal ecosystems. In this study we analyze the largest P. physalis stranding event historically recorded affected Cuba’s northwestern coast in December 2022. We counted all colonies during the massive event along ~ 3 km coast, within a 5 m stripe. Density, dimorphic form (left/right-handed), and colony size were quantified using 0.25 m2 quadrat placed every 50 m, 10 m from shoreline. Eighty-five people were stung, with 38 having strong allergic reactions, resulting in a health risk. Over ten thousand colonies were recorded, with the highest mean colony density (29.3 per m2) ever reported. The massive stranding coincided with the lowest Arctic Oscillation index (-2.59) in the past 11 years during December, likely linked to climate change. This led to the emergence of northeasterly winds reaching speeds of up to 24 km/h. Wind direction and speed, coupled with the dominance of left-handed colonies (71.4%), suggest the Sargasso Sea as the possible source of the bloom. The high prevalence of juvenile P. physalis colonies (68 %) likely aligns with the autumn breeding season in the northern hemisphere. The potential causes of P. physalis blooms are still poorly understood. Systematic monitoring of the distribution and abundance of this species should be a research priority considering the potential risk to human health and that the blooms could become more frequent and affect other areas in the Atlantic, given climate change and increasing eutrophication of the oceans.
Redox Metabolism and Vascular Calcification in Chronic-Kidney Disease
Authors: Alonso-Montes Cristina , Carrillo-López Natalia , Panizo Sara , Martín-Carro Beatriz , Mayo Barrallo Juan Carlos , Román-García Pablo , García-Castro Raúl , Fernández-Gómez Jesús M. , Hevia-Suárez Miguel A. , Martín-Vírgala Julia , Fernández-Villabrille Sara , Martínez-Arias Laura , Vázquez Sara Barrio , Calleros Basilio Laura , Cannata-Andía Jorge Benito , Naves-Díaz Manuel , Fernández-Martín José Luis , Quirós-González Isabel
Published: July 2023

Vascular calcification (VC), is a common complication in patients with chronic kidney disease and increases mortality. Although oxidative stress is involved in the onset and progression of this disorder, the specific role of some main redox regulators such as catalase, the main scavenger of H2O2, remains unclear. In the present study, epigastric arteries of kidney transplant recipients, an in vivo model of VC and an in vitro model of VC exhibiting catalase overexpression (Cts) were analyzed. Peri-calcification areas of human epigastric arteries have increased levels of catalase and cytoplasmic rather than nuclear RUNX2. In the in vivo model, advanced aortic VC concurs with lower levels of the H2O2 scavenger, glutathione peroxidase 3 compared to controls. In an early model of calcification using vascular smooth muscle cells (VSMCs), Cts VSMCs showed the expected increase in RUNX2 total levels. However, Cts VMSC also exhibited lower percentage of the nucleus stained for RUNX2 in response to calcifying media. At this early model of VC we did not observe dysregulation of mitochondrial redox state, an increase in general redox state was observed in the cytoplasm. These in vivo and in vitro results highlight the complex role of antioxidant enzymes as catalase in the process of VC by regulation of RUNX2 location.
Breeding Novel Rice Hybrids for Aerobic Ecology: A Way-Out from Global Warming and Water Crisis
Authors: Srijan Ambati , P Senguttuvel , Dangi Kuldeep Singh , S Sudheer Kumar , Sundaram Raman Meenakshi , D Srinivasa Chary
Published: July 2023

An experiment was conducted in 2016 & 2017 for development of novel rice hybrids for aerobic ecology with lesser yield penalties in comparison to irrigated ecosystem, further with added advantage of reduced methane emissions and water budget as witnessed in irrigated system. Based on the restorer / maintainer reaction and spikelet fertility (%), 10 restorer lines were selected to cross with 3 CMS lines in the line by tester fashion in Yasangi (summer) season 2016-17. Resulting 30 experimental hybrids besides 13 parental lines (10 Restorer lines and 3 B - lines of akin CMS lines) and checks (GK 5022, CR Dhan 201) assessed during Vankalam (rainy) season 2017 at three different places/locations viz., Rajendranagar, Warangal and Kampasagar. The outcome of experiment were two experimental hybrids viz., APMS-6A × HRSV – 7 and IR-79156A × ATR – 372, were categorized as stable hybrids with desirable sca effects, heterosis (ranging from 7% to 13%) over best check GK 5022 along with an in-essence performance for yield and other yield attributing characters.
Sustainable and Energy Saving Model Research for Existing Housing Stocks; Field Study
Authors: Polat Hasan , Yıldırım Muhammed
Published: July 2023

Although buildings constitute 35% of global energy use and 38% of carbon emissions from energy, the amount of energy and energy-related carbon emissions are increasing rapidly. On the other hand, non-renewable usable energy resources are decreasing on the contrary. New buildings are being built due to the increasing population and the existing building stock not meeting the needs or losing its lifespan. Some of the existing building stock is demolished and renewed for structural reasons and some for reasons such as usage performance. It is possible to reduce both energy consumption and greenhouse gas emissions with strategic energy uses in existing building stocks. There are various techniques to measure the maximum performance of sustainable and energy-efficient use of existing building stocks with which changes. Building Information Modeling (BIM) technology is one of these techniques that provides wide opportunities to users in recent years, and it is almost a virtual laboratory of structures. Building stocks can be modeled with BIM, and alternative shell and system suggestions can be used to measure how building performance has changed and to achieve the best results. In this research study, improvement scenarios that optimize energy use in existing building stocks are investigated on a sample residential building by using the virtual laboratory facilities of BIM. After measuring the current energy performance of the existing building with BIM tools, 192 alternative results were obtained with 6 variables (external walls, roof, insulation layers, transparent surface materials, lighting, and photovoltaic panels). The obtained alternatives were compared with the current state of the existing building. The material expenditures and amortization periods required for these alternative scenarios are also calculated. The results obtained were evaluated according to annual / lifetime energy consumption, fuel, electricity, initial investment costs, energy use intensity, and carbon emission amounts. With the optimization of the current situation of the sample building, annual fuel consumption decreased by 61% and electricity consumption by 64%. The amortization period of the optimum improvement was determined as 12 years.
The Preventive Effects of Statin on Lung Cancer Development in Patients with Idiopathic Pulmonary Fibrosis Using the National Health Insurance Service Database in Korea
Authors: Lee Yoo Jung , Kang Nayoon , Nam Junghyun , Lee Eung Gu , Ryoo Jiwon , Kwon Soon Seog , Kim Yong Hyun , Kang Hye Seon
Published: July 2023

Little is known about the effect of statin use in lung cancer development in idiopathic pulmonary fibrosis (IPF). We analyzed the database of the National Health Insurance Service to further investigate the clinical impacts of statin on lung cancer development and overall survival (OS) in IPF patients. The analysis included 9,182 individuals diagnosed with IPF, of which 3,372 (36.7%) were statin users. Compared to statin non-users, the time from diagnosis of IPF to lung cancer development and OS were longer in statin users in IPF patients. In Cox proportional hazard regression models, higher statin compliance, statin use, and being female had an inverse association with lung cancer risk, while older age at diagnosis of IPF and smoking history were associated with higher risk of lung cancer in IPF patients. For OS, statin use, female sex, higher exercise frequency, and diabetes were associated with longer survival. In contrast, older age at diagnosis of IPF and smoking history were associated with shorter OS in IPF patients. These data from a large population indicate that statin had an independent protective association with lung cancer development and mortality in IPF patients.
Gastric Alimetry® Test Interpretation in Gastroduodenal Disorders : Review and Recommendations
Authors: Foong Daphne , Calder Stefan , Varghese Chris , Schamberg Gabriel , Xu William , Daker Charlotte , Ho Vincent , Andrews Christopher N. , Gharibans Armen A. , O’Grady Greg
Published: July 2023

Chronic gastroduodenal symptoms are prevalent worldwide, and there is a need for new diagnostic and treatment approaches. Several overlapping processes may contribute to these symptoms, including gastric dysmotility, hypersensitivity, gut-brain axis disorders, gastric outflow resistance, and duodenal inflammation. Gastric Alimetry® (Alimetry, New Zealand) is a non-invasive test for evaluating gastric function that combines body surface gastric mapping (high-resolution electrophysiology) with validated symptom profiling. Together, these complementary data streams enable important new clinical insights into gastric disorders and their symptom correlations, with emerging therapeutic implications. A comprehensive database has been established, currently comprising >2,000 Gastric Alimetry tests, including both controls and patients with various gastroduodenal disorders. From studies employing this database, this pa-per presents a systematic methodology for Gastric Alimetry test interpretation, together with an extensive supporting literature review. Reporting is grouped into four sections: Test Quality, Spectral Analysis, Symptoms, and Conclusions. This review compiles, assesses, and evaluates each of these aspects of test assessment, with discussion of relevant evidence, example cases, limitations, and areas for future work. The resultant interpretation methodology is recommended for use in clinical practice and research to assist clinicians in their use of Gastric Alimetry as a diagnostic aid, and is expected to continue to evolve with further development.
Prognostic Relevance of Tumor-Infiltrating Immune Cells in Cervix Squamous Cell Carcinoma
Authors: Wild Carl Mathis , Garrido Fabian , Dannecker Christian , Köpke Melitta B , Chateau Marie-Christine , Boissière-Michot Florence , Heidegger Helene H , Vattai Aurelia , Kessler Mirjana , Jeschke Udo , Cavaillès Vincent
Published: July 2023

There exists a variety of studies about tumor-infiltrating lymphocytes (TILs) in cervical cancer, but their prognostic value in correlation to the histopathological subtype was never investigated. Therefore, the aim of this study was to quantify TILs in a panel of 250 sporadic cervical cancers and investigate the correlation with cervical cancer subtype and patient survival. TIL levels were significantly increased in the subgroup of squamous cell carcinomas in comparison to adenocarcinomas. In squamous cell carcinomas, TIL infiltration shows a negative correlation to age, FIGO stage and to the histone protein modification H3K4me3. Moreover, in adenocarcinomas, it was positively correlated to p16 and to the glucocorticoid receptor and inversely correlated to the MDM2 protein and to H3K4me3. Interestingly, immune infiltration was an independent positive prognosticator for disease free survival (DFS) in patients with squamous cell carcinomas, those bearing tumors with the strongest TIL infiltration showing the better DFS. Altogether, the present study provides a differentiated overview of the relations between TIL levels and prognosis in patients with cervix squamous cell carcinomas vs patients with cervix adenocarcinomas.
Truth-O-Meter: Collaborating with LLM in Fighting its Hallucinations
Authors: Galitsky Boris A.
Published: July 2023

A text obtained by a Large Language Model (LLM) such as GPT4 usually has issues in terms of incorrectness and hallucinations. We build a fact-checking system 'Truth-O-Meter' which identifies wrong facts, comparing the generation results with the web and other sources of information, and suggests corrections. Text mining and web mining techniques are leveraged to identify correct corresponding sentences; also, the syntactic and semantic generalization procedure adopted to the content improvement task. To handle inconsistent sources while fact-checking, we rely on an argumentation analysis in the form of defeasible logic programming. We compare our fact checking engine with competitive approach based on reinforcement learning on top of LLM or token-based hallucination detection. It is observed that LLM content can be substantially improved for factual correctness and meaningfulness.
Herbivory and Invasive Plant Species dynamics in Protected Rangelands: A Case for Conservation of Hell’s Gate National Park, Kenya
Authors: Gichure Moses K. , Nyaga Justine M. , Ngendo Rossa N. , Nyabuga Franklin N.
Published: July 2023

The status of vegetation and the impacts of mammalian herbivores on rangelands are complex, and such studies in Kenya are scanty. We investigated the dynamics of ground cover vegetation in Hell’s Gate National Park in relation to mammalian herbivory. Removal of palatable vegetation is postulated to enhance the development of invasive plant species. We investigated the influence of mammalian herbivores on vegetation diversity and dynamics in this rangeland. Three sampling blocks approximately 3 Km apart measuring 100 m x 50 m were established, each divided into three belt-transects (100 m x 10 m), and separated by a 10 m buffer zone. 2 m by 2 m quadrats at 20 m intervals were established in each transect. We measured composition the richness of plant and mammal species, and herbivory levels four times for six months (September 2018 to February 2019). Plant cover (P< 0.001) and species diversity (P< 0.001) differed significantly among sampling blocks and between seasons (P< 0.001). Non-metric multidimensional scaling of plant species and herbivores showed co-occurrence of Zebras with Sida tenuicarpa and giraffes with Solanum incunum. We conclude that the removal of preferred plants through herbivory may be giving an edge to invasive species in the park.
Gênero no (do) Referencial Curricular Amapaense para o Ensino Infantil e o Ensino Fundamental
Authors: Sardinha Antônio Carlos , Souza Silva David Junior de , Reis Marcos Vinicius de Freitas
Published: July 2023

O artigo problematiza as perspectivascentrais para compreensão das estratégiase lógicas de legitimação e inserçãodas questões de gênero no currículo deensino básico do Amapá. A pesquisa serealiza a partir da análise do documentodo Referencial Curricular Amapaensepara o Ensino Infantil e o Ensino Fundamental(RCA). Nesse documento, a categoriade gênero é trabalhada quase exclusivamenteno componente deHistória. No RCA, o gênero é tratado deforma rudimentar no documento em seuconjunto e a ausência de uma propostade educação em Direitos Humanos acentuaa exclusão do tratamento das relaçõessociais de gênero em um contextointegrado e interdisciplinar capaz de perpassaro currículo em sua totalidade.
Histórias locais, memórias e identificações: trabalhadores no ensino escolar de História
Authors: Moreno Jean Carlos , Lima Adilson Carlos , Bueno Mariane Melo
Published: July 2023

O presente artigo, na perspectiva dos estudossobre ensino de História Local,aborda elementos dos processos que estruturaramuma narrativa mistificada eseletiva acerca dos trabalhadores pobresdos pequenos municípios de Figueira--PR e Tejupá-SP. Propõe-se, assim, umduplo foco na História do Trabalho e naHistória Local como forma de enfrentamentodas prescrições curriculares rígidasna construção de espaços de ressignificaçãoda aprendizagem escolar deHistória. Centrando-se nos conceitos dememórias e identificações, o ensino deHistória é entendido como um espaçode superação das tradições seletivas, quedistorcem a realidade. Dessa maneira,defende-se um ensino escolar de Históriaque possibilite aos alunos da EducaçãoBásica a condição de perceber ossentidos das narrativas que circundamsua vivência e, a partir disso, proporcionea formação de indivíduos capazes deagir de maneira crítica e autônoma.
A História do Brasil entre “mundos” e a excepcionalidade europeia: a Base Nacional Curricular Comum (2014-2018)
Authors: Macedo André Luan Nunes
Published: July 2023

O presente artigo estabelece uma comparaçãoentre a primeira versão da BaseNacional Comum Curricular (BNCC)de História (2014) e sua última, publicadano governo de Michel Temer (2018).É parte de nossa tese de doutoramento,cuja proposta foi analisar a história doeurocentrismo nos livros didáticos e políticascurriculares. A leitura das diferentesversões da BNCC foi feita emconjunto com a leitura dos pareceres,encomendados pelo Ministério da Educação,de historiadores conhecidos pelasua contribuição acadêmica. Afinal,quais são as diferenças entre a primeiraversão da BNCC – anterior ao governode Michel Temer – e a versão explicitamenteeurocêntrica? Essa é a principalquestão a que buscamos responder nessetrabalho.
Sintomas de crise na História? Investigando regimes de historicidade em discursos sobre a história do Brasil
Authors: Klüppel Giuvane de Souza
Published: July 2023

Partindo de problematizações recentes sobrea disciplina História, realizamos nesteartigo a análise de 277 discursos sobre ahistória do Brasil escritos por jovens deidade entre 12-24 anos da cidade de PontaGrossa, no Paraná. Para operacionalizaçãodas fontes, utilizamos de alguns softwarespara dispor os discursos em umgrafo, que foi organizado a partir da relaçãoestabelecida entre as diversas palavrasque formam o conjunto discursivo. Cotejamoso produto da análise com problematizaçõesacerca dos conceitos de “presentismo”e “atualismo”, na perspectivade compreender o regime de historicidade.Os resultados expressam que mençõesao futuro e efeitos do conhecimento históricopara fins práticos de orientação temporalnão são mobilizados diretamente nodiscurso histórico dos jovens. Além disso,é nítido que as parcas alusões a uma ideiade futuro, assim como as referências aopassado, são projeções do seu próprio presente,não apresentando novidade temporalna relação entre os tempos.
Formando historiadores em meio à crise pandêmica
Authors: Soares Jandson Bernardo , Souza Juliana Teixeira
Published: July 2023

Tendo aderido ao ensino remoto paradar continuidade às aulas dos cursos degraduação em História durante a pandemiada Covid-19, neste artigo relatamosnossas primeiras experiências comesse formato, colocando em execuçãoum plano de curso que propunha criarsituações de aprendizagem que estivessemfocadas nos/as estudantes e noexercício do método histórico, considerandoos diversos espaços de atuação doprofissional de História. O desafio eraenfatizar a dimensão prática da metodologiada História e estabelecer, no espaçovirtual, um ambiente de ensinoque fosse estimulante e provocativo paraestudantes que enfrentavam a crisesanitária e suas repercussões econômico-sociais. Confrontando os objetivospropostos e os resultados alcançados,privilegiando a perspectiva dos estudantes,concluímos com algumas propostassobre o que ensinar e como ensinar Histórianos cursos de formação inicial.
Entrevista com Joana Neves: O ensino de História e as utopias: memórias dos Colégio Vocacionais e de uma professora da primeira geração do “campo” do ensino de História
Authors: Hoissa Benfica Tiago Alinor
Published: July 2023

Joana Neves nasceu em 15 de outubro de 1942. É professora aposentada da Universidade Federal da Paraíba, desde 1995. Foi aluna da USP na graduação e no mestrado, e após a aposentadoria, defendeu sua tese de doutorado na mesma instituição. Joana é professora formada desde 1966, iniciando a docência profissional no Ginásio Vocacional EmbaixadorMacedo Soares, em Barretos-SP, e, de 1968 a 1970, na condição de professora de História, integrou a equipe da Área de Estudos Sociais nos Cursos Técnicos do Segundo Ciclo do Colégio Estadual Osvaldo Aranha, em São Paulo/SP.  Em 1970, com o fim das escolas experimentais e o fechamento do Serviço de Ensino Vocacional no estado de São Paulo, ela recebeu o convite de lecionar em Aquidauana, então município do estado de Mato Grosso, na recém fundada Universidade Estadual de Mato Grosso/UEMT que, a partir de 1978, com a divisão do estado, tornou-se a Universidade Federal do Mato Grosso do Sul. Ainda antes de defender o mestrado, ocorrido em 1981, no ano de 1978 Joana começa a lecionar na Universidade Federal da Paraíba, onde permaneceu vinculada até a aposentadoria. A bibliografia, ou melhor, muitos textos de Joana, ainda não foram devidamente reunidos e publicados. Na sua trajetória, destacam-se a parceria que tivera com Elza Nadai em muitos escritos de livros didáticos, textos acadêmicos, e a participação na elaboração, na década de 1970, do Guia Curricular do estado de São Paulo, conhecido como “Verdão”. A biografia profissional de Joana transpassa a maior parte da segunda metade do século XX. Mesmo não tendo o perfil do atual homo academicus, a posição institucional e o capital social da mesma era privilegiado no espaço universitário brasileiro. De fato, Joana contribuiu com muitos escritos sobre ensino de História e história regional, na formação de muitos professores e teve uma destacada atuação na ANPUH.
A vida como mestra da história, a vida como mestra da escola
Authors: Gonçalves Marcia de Almeida
Published: July 2023

A complexidade do conceito de crise é,neste artigo, ponto de partida de reflexõessobre a mobilização de narrativasvivenciais no ensino/aprendizagem daHistória. Busca-se compreender comosituações de crise afetam as vidas porelas atravessadas, priorizando vozes esujeitos, em especial os/as que vieram aser silenciados/as e apagados/as de determinadasformas de registrar e narrarsituações de crise, nas suas respectivashistoricidades. O caminho escolhido paraabordar vidas em situações históricasde crise se bifurca em dois sentidos: naapropriação do conceito de vidas precárias,no diálogo com Judith Butler, e, emcomplementaridade, na ponderação sobreo ato de narrar histórias de vida emcondições de precariedade como escolhapedagógica e ético-política, na defesa dodireito ao luto de sujeitos e grupos afetadospela banalização da violência.