bluuebunny/crossref_metadata_2025 huggingface dataset:
A Prospective Observational Study to Evaluate the Prevalence of Adverse Drug Reactions and its Impact on Quality of life in Psychiatric Patients at a Tertiary Care Teaching Hospital
Authors: Patel Megha , Patel Harsh , Hadia Rajesh , Kataria Lakhan , Gohel Kushalkumar , Bhil Dipika , Rajput Hemraj S. , Maheshwari Rajesh
Published: November 2023

Background:

In recent times, emphasis on pharmacovigilance (PV) is elevated due to increased cases of adverse drug reactions (ADRs) coming into notice. Psychotropic medications that are the mainstay of treating psychiatric patients are linked to various adverse drug reactions. The given study lays accentuation on determining the pattern of ADRs due to the use of antipsychotics and antidepressants.

Objectives:

In this study, we aim to determine the incidence of ADRs and their effect on the quality of life (QOL) of the patients after the ADR (s).

Methodology:

This is a prospective observational study of a total of 300 subjects receiving antipsychotics and/or antidepressants. They were screened for possible ADRs. Possible risk factors for the development of ADRs were also assessed. The difference in the pattern of ADRs in patients prescribed with Antidepressants (ADs) and/or Antipsychotics (APs) was observed. The average number of APs and/or ADs per prescription was calculated. The causality and severity assessment of the observed ADRs was done by the World Health Organization-Uppsala Monitoring Center (WHO-UMC) scale, Naranjo’s algorithm, and Hartwig–Siegel scale, respectively. Lastly, the impact of ADRs on the QOL of the patients receiving APs and/or ADs was evaluated.

Results:

The prevalence of ADRs in patients receiving APs and/or ADs is 24.33%. Olanzapine is the most commonly prescribed AP while sertraline is the most commonly prescribed AD. Olanzapine and sertraline are responsible for the highest number of ADRs as AP and AD, respectively. Females are found to be at higher risk for developing ADRs. Multiple comorbidities and polypharmacy are also considered to be possible risk factors. The average number of APs and/or antidepressants per prescription is 1.94 drugs. APs are found to be responsible for a higher number of ADRs in comparison with ADs. The maximum number of ADRs falls into the possible criteria of causality assessment by the WHO-UMC scale and Naranjo’s algorithm. All the observed ADRs fall into the mild and moderate category of severity by the Hartwig–Siegel scale. The ADRs have a significant impact on the physical health and psychological domain of QOL assessment.

Conclusion:

The need for PV is highlighted by the results obtained in this study. Intense monitoring and increased awareness can help improve the rate of ADR (s) occurrence in patients receiving psychotropic medications. As a result, the impact of ADRs on the QOL of the patients can also be reduced.
Теорема Гамильтона-Кэли и представление резольвенты
Authors: Kostrub Irina Dmitrievna
Published: November 2023

Для сопровождающей алгебраическое (дифференциальное) уравнение в комплексной банаховой алгебре матрицы Фробениуса доказана теорема Гамильтона-Кэли, которая используется для получения представления резольвенты.
Свободная топологическая алгебра с раздельно непрерывной операцией Мальцева
Authors: Sipacheva Ol'ga Viktorovna , Solonkov Alexander Alexeevich
Published: November 2023

Статья посвящена топологическим пространствам с раздельно непрерывной операцией Мальцева, которые мы называем квазимальцевскими пространствами. Доказано существование свободного квазимальцевского пространства, порожденного произвольным тихоновским пространством, и показано, что всякое квазимальцевское пространство является факторпространством свободного квазимальцевского пространства. Кроме того, показано, что топология свободного квазимальцевского пространства имеет простое и естественное описание в терминах порождающего пространства. Наконец, доказано, что всякое тихоновское квазимальцевское пространство является ретрактом квазитопологической группы.
Antigout Activity of The Spatholobus littoralis Hassk. Extract Fractions Against Xanthine Oxidase: Its Metabolite Profile and Inhibition Kinetics
Authors: Sianipar Rut Novalia Rahmawati , Sutriah Komar , Iswantini Dyah , Trivadila  , Achmadi Suminar Setiati
Published: November 2023

The Spatholobus littoralis Hassk. (S. littoralis Hassk.) is a native plant in Indonesia and has been widely used in traditional Dayaknese medicine for non-communicable degenerative diseases. One of these illnesses, known as gout, is caused by excessive uric acid in the blood, which is the catalytic byproduct of a xanthine oxidase (XO) enzyme. In this work, we investigated the inhibition kinetics of XO and identified bioactive compounds from the stem extract fractions of S. littoralis Hassk. using liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). Fractionation was carried out to obtain n-hexane, dichloromethane, and 1-butanol fractions from the water and 70% ethanol extracts. Fraction of 1-butanol from 70% ethanol and water extract displayed potent inhibitors of XO with IC50 value 116.91±3.51 and 137.15±5.00 mg/L, respectively. Lineweaver-Burk plot analysis showed that the 1-butanol fraction from the two extracts inhibited XO competitively. The 1-butanol fraction from the two extracts has been further identified as a bioactive fraction. The majority of the compounds in the two active fractions were phenolics. These findings revealed that the 1-butanol fraction from the two extracts is promising as an antigout treatment in the future.
Effects of magnetization and heat transfer on electrically conducting magnetohydrodynamics flow with mixed convection flow over porous duct
Authors: Dagareh Mam Ishaku , Ighodalo Ehapa Harper , Hafeez Hafeez Yusuf , Mohammed Jibrin , Muhammad Ahmad , Ndikilar Chifu E.
Published: November 2023

The effects of magnetic field and heat transfer problem on incompressible magnetohydrodynamics (MHD) mixed unsteady convective flow of an electrically conducting viscous fluid in a duct filled with a porous medium are investigated. The fluid flow is subjected to an applied uniform magnetic field vertical to the duct and uniform free stream of constant velocity and temperature. The system of nonlinear differential equations governing flow and heat transfer phenomena are derived and reduced into a set of ordinary differential equations using the auxiliary variable method. The reduced equations are solved numerically using Runge-Kutta method associated with slip boundary conditions. The graphical results for velocity, temperature and heat transfer rate are obtained using MATLAB software. It is observed that the velocity profiles increase with an increase of similarity parameter (fI) while temperature gradient decreases rapidly with an increase of similarity parameter (θI) for different values of Grosh number, Magnetization and Prandtl number respectively.
Determination of annual effective dose equivalent and the excess lifetime cancers risk in water samples from a mining site in Jayfi, Pago Tungan Goro of Minna, Niger State, Nigeria
Authors: Abdulkarim M. S. , Nurudeen A. A. , Abdullateef O. O.
Published: November 2023

Mining industry in Nigeria provides economic benefit of wealth creations and employment opportunities, however, the industry is associated with negative health impact to miners and the surrounding communities resulting from mining processes. Gross alpha and beta radionuclide activity of water sources from Jayfi, Pago of Tungan Goro, Minna, Niger state was carried out. Eleven water samples were collected from the farming, residential/commercial, and industrial zones in the community and were analyzed using the protean instrument corporation (PIC) MPC 2000DP, single channel proportional counters. Two radiological parameters, which are the Annual Effective Dose Equivalent (AEDE) and Excess Lifetime Cancer Risk (ELCR) were determined. We are assuming 70years as the average duration of life for humans, the results gotten are; AEDE (α and β) 0.013237/0.645534mSv/y and ELCR (α and β)0.280742/1.77 X 103 respectively. This shows that the concentrated values of beta are much higher than their corresponding values of alpha and ICRP accepted values of 0.5Bq/L for alpha and 1Bq/L for beta show elevated values.
Determination of radiation hazard indices (Annual Gonadal Dose Equivalent) in water samples in the vicinity of mining site in Minna, Niger State, Nigeria
Authors: Abdulkarim M. S. , Nurudeen A. A. , Abdullateef O.O.
Published: November 2023

The gross alpha and beta radionuclide activity of source of water from mining site in Minna, Niger state has been carried out. Eleven water samples were collected from the farming, residential/commercial, and industrial zones in the community and were analyzed using the protean instrument corporation (PIC) MPC 2000DP, single channel proportional counters. Annual Gonadal Dose Equivalent (AGDE) was determined. AGDE α and β 20.254399/3.088977mSv/y. This shows that the calculated values of alpha in BHL3 are above the accepted value for ICRP. Moreover, the calculated values of beta in BHL1 are above the accepted value for ICRP. It can be observed that all the remaining values for alpha and beta are below the ICRP values of 0.5Bq/L for alpha and 1Bq/L for beta.
Serum biochemical parameters profile of Wistar rats following daily administration of some food spices
Authors: Itopa Ahmad, Abdulrazaq , Suleiman Abdulrahman Itopa , Dauda Shaibu Enehezeyi
Published: November 2023

Garlic, ginger, and turmeric are widely used together or individually as spices in food or for their different medicinal purposes all around Nigeria. This study was conducted to assess the effects of consuming either of the three samples on the livers of wistar rats. Standard methods of analyses were employed for the study. A set of fifteen male Wistar Rats divided equally into three groups of which group I served as control and groups II and III as test groups were used for each of the samples; a total of 45 wistar rats were used for this study. The rats in the test groups for each of the samples were placed on different concentrations (group II: 100 mg/kg Body Weight and group III: 200 mg/kg BW) of the sample extract for 21 days. Results obtained reveal that ethanol extracts (100 mg/kg BW and 200 mg/kg BW) of garlic significantly (p<0.05) reduced the liver enzymes Alanine Aminotransferase (ALT) and Alkaline Phosphatase (ALP), and the bilirubin levels but significantly (p < 0.05) reduced Aspartate Aminotransferase (AST) against the control. However, ginger extracts and turmeric extracts significantly (p<0.05) increased ALT and AST in the test groups against the control, and while ginger extracts significantly (p<0.05) increased the levels of bilirubins, turmeric extracts significantly (p<0.05) reduced the levels of bilirubins in the attest groups against the control. The significant decrease in the levels of ALT, ALP, total and conjugated bilirubin levels by garlic extracts shows garlic hepatoprotective potential while the significant increase in the levels of ALT and AST by ginger extracts and turmeric extracts shows their hepatotoxic potential to the body of the experimental animals employed.
Amino acid composition and angiotensin-i converting enzyme inhibitory activity of Cowpea (Vigna unguiculata) pepsin-pancreatin protein hydrolysate fractions
Authors: Abubakar Salisu Maiwada , Adekale Idris Adediran , Hashidu Abdulaziz Shehu
Published: November 2023

Legumes are high in protein and have been linked to the management and prevention of chronic diseases due to their bioactive components. This study investigated the amino acid composition of cowpea protein hydrolysate and its inhibitory impact on angiotensin-I converting enzyme (ACE-I). Cowpea (Vigna unguiculata) protein hydrolysate (CPH) was produced through sequential digestion with pepsin and pancreatin. CPH was then separated using G-50 gel filtration chromatography and reverse phase high performance liquid chromatography (RP-HPLC). The fractions' ACE-I inhibitory activity was then assessed. The IC50 value for the RP-HPLC fraction with the highest ACE-I inhibitory activity (P<0.05) was 6.23 μg/mL. The amino acid profile revealed that a large proportion of hydrophobic amino acids were present in the RP-HPLC fraction containing the peptide with the highest ACE-I inhibitory activity. These findings suggest that CPH has the potential to be employed in the development of functional foods that can aid in the prevention and treatment of hypertension.
Corpus Analysis with spaCy
Authors: Kane Megan S.
Published: November 2023

This lesson demonstrates how to use the Python library spaCy for analysis of large collections of texts. This lesson details the process of using spaCy to enrich a corpus via lemmatization, part-of-speech tagging, dependency parsing, and named entity recognition. Readers will learn how the linguistic annotations produced by spaCy can be analyzed to help researchers explore meaningful trends in language patterns across a set of texts.
Cseresznyés- és Meggyeskertek Silviu Purcărete, Dragoș Buhagiar és Helmut Stürmer színházi világában
Authors:   Babeș-Bolyai University, Cluj-Napoca, Demeter Kata
Published: November 2023

In my doctoral research, I focus on the visual world of performances and the work of scenographers, but since the director’s concept and the scenographer’s work seem to be inseparable, I needed to approach the topic from the perspective of the act of directing. That’s why I analyze in my research the collaborative productions of Silviu Purcărete as a director with scenographers Helmut Stürmer and Dragoș Buhagiar – like “The Cherry Orchard” produced by the Budapest National Theatre in 2019. It has also proven beneficial to examine the visual world of the scenographers in productions with other directors too, because it provides a broader understanding of their work, independent of the directorial concept and extends the research beyond a single creative process. In this case the analysis of their joint production of “The Cherry Orchard” was accompanied by the iconic 1998 performance by Vlad Mugur, whose memorable space was designed by Stürmer, and the analysis of the latest performance by Yuri Kordonsky in 2021, whose stage design praises Buhagiar’s work. These three performances and the analysis of their visual world form the basis of this study.
Simulation and Measurement Analysis of an Integrated Flow Battery Energy-Storage System with Hybrid Wind/Wave Power Generation
Authors: Li Wang  , Shih-Chia Lin  , Sheng-Jie Zhang  , Ching-Chung Tseng  , Hung-Hsien Ku  , Chin-Lung Hsieh
Published: November 2023

This study aims to evaluate the power-system stability and the mitigation of fluctuations in a hybrid wind/wave power-generation system (HWWPGS) under different operating and disturbance conditions. This evaluation is performed by employing a vanadium redox flow battery-based energy storage system (VRFB-ESS) as proposed. The measurement results obtained from a laboratory-scale HWWPGS platform integrated with the VRFB-ESS, operating under specific conditions, are used to develop the laboratory-scale simulation model. The capacity rating of this laboratory-scale simulation model is then enlarged to develop an MW-scale power-system model of the HWWPGS. Both operating characteristics and power-system stability of the MW-scale HWWPGS power system model are evaluated through frequency-domain analysis (based on eigenvalue) and time-domain analysis (based on nonlinear-model simulations) under various operating conditions and disturbance conditions. The simulation results demonstrate that the fluctuations and stability of the studied HWWPGS under different operating and disturbance conditions can be effectively smoothed and stabilized by the proposed VRFB-ESS.
Da teoria à prática
Authors: Santos Emilson Oliveira dos
Published: November 2023

A BNCC coloca como dever da Geografia enquanto componente curricular o de desenvolver competências e habilidades que promovam o raciocínio geográfico partindo da análise de uma situação geográfica, proporcionando aos alunos compreenderem a espacialidade do fenômeno, ao passo que se tornem capazes de solucionar os problemas oriundos da relação entre sociedade e natureza. Mas para que isso aconteça, as aulas de Geografia devem partir de metodologias que promovam o protagonismo do aluno e a aplicação da teoria, vista em sala de aula, na resolução dos desafios presentes no cotidiano desse aluno. Nessa direção, o presente trabalho utiliza o Estudo do Meio como metodologia no Ensino de Geografia, objetivando efetivar o que pede a BNCC, partindo da análise do fenômeno Dengue, realizada com alunos de uma escola pública da capital piauiense. Desse modo, este trabalho parte da pesquisa teórica baseada em autores que se ocupam em discutir o Ensino de Geografia, o Estudo do Meio, da pesquisa documental com a análise da própria BNCC Geografia; e da pesquisa de campo que mostra a metodologia escolhida por este trabalho em ação. Conclui-se que o Estudo do Meio promove o que pede a BNCC Geografia no tocante ao desenvolvimento de habilidades e competências, proporcionando ao aluno ver sentido e significado nos conteúdos geográficos a partir da aplicação destes na resolução de problemas.
Palavras-chave
BNCC Geografia, Ensino de Geografia, Estudo do Meio.
 
From theory to practice: the BNCC Geography applied to the study of the environment
Abstract
The BNCC places as a duty of Geography as a curricular component to develop skills and abilities that promote geographic reasoning from the analysis of a geographical situation, providing students to understand the spatiality of the phenomenon, while becoming able to solve problems arising from the relationship between society and nature. But for this to happen, Geography classes must start from methodologies that promote the student's protagonist and the application of the theory seen in the classroom in the resolution of challenges present in the student's daily life. In this direction, this paper uses the Study of the Environment as a methodology in Geography Teaching, aiming to implement what the BNCC requires, based on the analysis of the Dengue phenomenon, conducted with students from a public school in the capital of Piaui. Thus, this work is based on theoretical research based on authors who discuss the Teaching of Geography, the Study of the Environment, documentary research with the analysis of the BNCC Geography; and the field research that shows the methodology chosen by this work in action. It is concluded that the Study of the Environment promotes what the BNCC Geography asks for with regard to the development of skills and competencies, providing the student to see sense and meaning in geographic content from the application of these in problem solving. 
Keywords
BNCC Geography, Geography Teaching, Environmental Study.
Khả năng sinh trưởng, phát triển và năng suất của một số giống bí đỏ trong vụ xuân hè năm 2022 tại tỉnh Thừa Thiên Huế
Authors: Trần Thị Ánh Tuyết , Nguyễn Thị Hoài , Trần Thị Thu Giang , Cao Giang Nam
Published: November 2023

Cây bí đỏ (Cucurbita pepo L.) là loại rau có giá trị dinh dưỡng và kinh tế cao, được trồng phổ biến ở nhiều địa phương. Nghiên cứu được tiến hành trong vụ Xuân Hè năm 2022 tại thành phố Huế, tỉnh Thừa Thiên Huế nhằm đánh giá khả năng sinh trưởng, phát triển và năng suất của 5 giống bí đỏ trong nước, từ đó tuyển chọn được 1 - 2 giống phù hợp với điều kiện sinh thái của địa phương. Thí nghiệm một yếu tố được bố trí theo kiểu khối hoàn toàn ngẫu nhiên với 3 lần nhắc lại, 5 nghiệm thức tương ứng với 5 giống gồm GNO3; Gold Star 998; Super Gold Star 999; Super Star 350 và Super Dream NP – 17. Kết quả cho thấy thời gian sinh trưởng của các giống từ 100 đến 110 ngày. Các giống có khả năng sinh trưởng nhanh, tốt là GNO3 và Super Dream NP - 17. Giống Gold Star 998 và Super Gold Star 999 ít bị nhiễm bệnh hơn các giống khác. Năng suất thực thu từ 21,58 - 101,73 tấn/ha, cao nhất là giống Super Star 350 đạt 101,73 tấn/ha, thấp nhất là giống Gold Star 998. Giống Super Star 350 có năng suất cao và khả năng nhiễm bệnh ít hơn các giống cùng tham gia thí nghiệm. Giống Super Star 350 và Super Gold Star 999 có thể được đưa vào sản xuất ở tỉnh Thừa Thiên Huế.
The Legacy and Prospect of Black Writers’ Commitment for Pan-Africanism
Authors:   Department of English, Senior Lecturer University Alassane Ouattara Bouaké, Côte d’Ivoire, M’BRA Kouakou
Published: November 2023

This article deals with the issue of black writers’ commitment for the implementation of Pan-Africanism. In fact, black writers in America, the Caribbean and Africa have developed an episteme that aims at reconnecting black people not only with their genuine cultural and historical matrix, but also at urging them to struggle for unity. Their literary oeuvre and actions posit Pan-Africanism as the required weapon for black empowerment and progress. This study unveils the transformation of Pan-Africanism throughout history. The Afrocentric perspective that underpins it, deconstructs the Western political, economic and cultural hegemony and advocates black agency through unity. This analysis, therefore, argues that black writers’ vision and action still operate as a fertile ground for the implementation of the ever-changing Pan-Africanism.
Posterior Reversible Encephalopathy Syndrome in Ischaemic Stroke with Malignant Hypertension, Chronic Kidney Disease, And Septic : A Case Report
Authors:   Department of Neurology, Mitra Keluarga Pondok Tjandra General Hospital, Sidoarjo, Indonesia, Agung Locoporta
Published: November 2023

Posterior Reversible Encephalopathy Syndrome (PRES) is a diagnosis based on neuroimaging with the finding of vasogenic edema, especially in the occipital and parietal lobes. Some of the risk factors include malignant hypertension, chronic kidney failure, organ transplantation, autoimmune, immunosuppressant drugs, chemotherapy, and sepsis. The PRES mechanism is due to disrupted autoregulation, especially in the posterior circulation which is associated with hypertension and hypoperfusion. This will cause damage to the blood-brain barrier and vasogenic edema. We report a woman, 70 years old, with the chief complaint of loss of consciousness accompanied by headache, vomiting, and restlessness. The patient has chronic hypertension and routine hemodialysis due to chronic kidney failure. On physical examination, the patient was somnolent, malignant hypertension, and hemiparesis sinistra. Imaging examination showed vasogenic edema of the right parietooccipital lobe. The patient was treated in the intensive care unit, given intravenous dexamethasone, antihypertension, antibiotic, and routine hemodialysis. Consciousness gradually improved.
Communication Harmonization Strategy between Al-Fikh Orchard Management with Construction Branch in Kuala Lumpur, Malaysia
Authors:   Universitas Muhammadiyah Sumatera Utara. Jl. Kapten Mukhtar Basri No. 3 Medan – Indonesia, Mavianti Mavianti , Zahriani JF Nurul ,   Universitas Muhammadiyah Sumatera Utara. Jl. Kapten Mukhtar Basri No. 3 Medan – Indonesia, Harfiani Rizka ,   Universitas Muhammadiyah Sumatera Utara. Jl. Kapten Mukhtar Basri No. 3 Medan – Indonesia, Chapakiya Abdurrohman ,   Fatoni University. 135/8 Tambon Khao Tum, Amphoe Yarang, Chang Wat Pattani 94160, Thailand – South Thailand
Published: November 2023

Success in establishing and maintaining harmonious communication in an educational institution will have an impact on the school's success in realizing its vision and mission. The differences in distance, mindset, and perception of each coach will of course give rise to new problems. However, it doesn't have to be a problem because these differences actually strengthen the determination to continue to advance Tadika al-Fikh Orchard. Researchers want to dig deeper into the communication harmonization strategy established by Al-Fikh Orchard Management with its Cawangan in Kuala Lumpur, Malaysia. So that the development of Tadika Al-Fikh Orchard is progressing rapidly as it is now. The founder certainly knows more about the vision and mission of the Al-Fikh Orchard. He is a person who really understands the goals to be achieved, the strategies for achieving them, the management of the process, the colleagues needed to support and help realize the educational mission promoted by Al-fikh Orchard. This research uses a qualitative approach, with a case study type of research conducted at Tadika Al-Fikh Orchard Kuala Lumpur, Malaysia. Data collection techniques were carried out by means of observation, interviews and documentation. The data analysis technique used is Spradley domain analysis. The data validity test technique uses the triangulation method. To test the effectiveness analysis, use the in-depth interview method to explore the information needed in this research. The results of the analysis are presented in qualitative descriptive terms. The results of the research found that the founder certainly cannot move alone in advancing Tadika, at least she really needs support from his husband as a good support system to realize his mission. The management must also prepare a program that can be implemented by the target branch. Apart from that, strong leadership and focus on the goals to be achieved are also strengths in dealing with the various characters of the team being built.
Authors: Prasetya Anton Surya , Dewi Apri Rahma , Aprilia Putri
Published: November 2023

Stress or anxiety is often experienced by final year students, especially in preparing their final assignment. Anxiety in students occurs because students are unable to overcome the difficulties encountered, including the repeated revision process, difficulty getting references, the length of time for feedback from supervisors, and limited research time. Overcoming the impact that occurs due to anxiety problems in final year students which causes the academic process to be not optimal and can be done with non-pharmacological therapies, one of therapy is storytelling can express feelings and music therapy can provide a sense of comfort. The aim of this study is the effectiveness storytelling and music therapy on the anxiety of final year students. This research quantitative research methods quasi experimental design with pre-dan post without control. The questionnaire used HARS (Hamilton Anxiety Rating Scale). The sample in the study consisted of 30 students with anxiety. The results of the study showed changes from pre and post after the intervention, based on the t test results obtained p value < 0.005, it is 0.000 so it can be concluded that there is an influence storytelling and music therapy on the anxiety of final year students. The conclusion from the study is that therapy storytelling and music therapy can reduce the anxiety level of final year students.
What do we Know about Corporate Debt Maturity Structure in Saudi Arabia?
Authors: Alnori Faisal Seraj
Published: November 2023

Abstract

This study examines the firm-specific and macroeconomic factors that influence corporate debt maturity structure in Saudi Arabia and explores whether existing theories can predict corporate debt maturity structure. The sample includes 121 listed non-financial firms operating in Saudi Arabia over the years 2010-2021 and employs a static ordinary least square (OLS) model before and after incorporating industry fixed effects. Approximately 52% of Saudi firms’ total debt consists of long-term debt, which is higher than other firms' long-term debt usage, operating in emerging markets. Furthermore, the study finds that both firm-specific and macroeconomic factors are important determinants of Saudi firms’ debt maturity structure decisions. The firm-specific determinants including leverage, profitability, size, liquidity, and asset maturity are positively related to corporate debt maturity choice. However, firms’ risk is negatively associated with debt maturity structure. Economic growth (GDP) has a positive linkage with corporate debt maturity, while the interest rate negatively impacts long-term debt maturity. The results support the matching theory, while it does not support the agency and the signaling theories. At best, this is one of the earliest studies that investigate the influence of firm-specific and macroeconomic factors on Saudi firms’ debt maturity structure decisions.

JEL classification numbers: G3, G32.
Keywords: Debt maturity, Firm-related factors, Macroeconomic factors, Saudi Arabia.
A Quest for Knowledge Democratization: Implications for Averting Africa’s Knowledge Dependency
Authors: Aga Firdissa Jebessa
Published: November 2023

The purpose of this study was to implicate Africa’s knowledge (in)dependency by assessing African universities’ knowledge production and dissemination gaps vis-à-vis indigenous knowledge, and constraints to- and opportunities for- knowledge democratization. A qualitative approach was employed to generate information by reviewing extant literatures and conducting interviews. The results have shown that there were constraints emanating from historical antecedents; ideology; Eurocentric and global North/West epistemic dominance; re-westernization designs, African resource, technology, and science limitations; and language barriers to participate in knowledge co- creation. As a result, African universities and intellectuals were not sensitive to the interests and needs of their research communities and subjects. Whereas there were opportunities to democratize knowledge, failure to expedite them catapulted the constraints/hurdles to reinforce power imbalance, to exacerbate the gaps/conflicts, and to sustain African Knowledge dependency. This, therefore, calls for revitalizing and reinvigorating concerted energies and talents to connect knowledge production to practical concerns of everyday life of the knowledge users and/or participants; and to engage in production and utilization of relevant, responsive, and competent knowledge responsive to methodological, epistemological, ontological, and socio-political realities.
Transfer Learning for Lung Nodules Classification with CNN and Random Forest
Authors: Yahya Saleh Abdulrazak , Ka Chin Chee , Ameera Rosdi Ros
Published: November 2023

Machine learning and deep neural networks are improving various industries, including healthcare, which improves daily life. Deep neural networks, including Convolutional Neural Networks (CNNs), provide valuable insights and support in improving daily activities. In particular, CNNs enable the recognition and classification of images from CT and MRI scans and other tasks. However, training a CNN requires many datasets to attain optimal accuracy and performance, which is challenging in the medical field due to ethical worries, the lack of descriptive notes from experts and labeled data, and the overall scarcity of disease images. To overcome these challenges, this work proposes a hybrid CNN with transfer learning and a random forest algorithm for classifying lung cancer and non-cancer from CT scan images. This research aims include preprocessing lung nodular data, developing the proposed algorithm, and comparing its effectiveness with other methods. The findings indicate that the proposed hybrid CNN with transfer learning and random forest performs better than standard CNNs without transfer learning. This research demonstrates the potential of using machine learning algorithms in the healthcare industry, especially in disease detection and classification.
Rol de la mujer en Afganistán tras la retoma del poder Talibán 2021-2022
Authors: Cañon Cardona Alejandra
Published: November 2023

Este artículo de investigación busca analizar el rol de la mujer en Afganistán después de la retoma del poder talibán en 2021, a partir de la perspectiva del feminismo islámico desde el enfoque de la hermenéutica feminista del Corán. Esto se hizo a partir de la metodología cualitativa de investigación, con un diseño de teoría fundamentada. De esta forma, se pudo identificar que el rol de la mujer afgana en la sociedad contradice los postulados del feminismo islámico debido a las violaciones de los derechos de las mujeres, justificadas bajo las interpretaciones patriarcales de los textos del Islam. Es así como las políticas del régimen talibán, implementadas bajo una interpretación radical del Islam, condicionaron el rol de la mujer afgana.
ZOROASTRIANISM: A SCHISM, TURAN'S SEPARATION FROM TENGRISM
Authors:   Turan» University, Alshanov Rakhman
Published: November 2023

The article is devoted to certain issues of the spread of Tengrism in Central Asia, the problem of religious schism, the separation of Zoroastrianism from the depths of Tengrism. The article focuses on the answers of Zarathushtra to the worldview questions of Bairi Akhun, it is shown that Zarathushtra in search of adherents of the new belief acts as the reformer, later this act was characterized by the prophetic co-religionists, his ten-year activity to promote his radically new ideas is perceived as heretical and schismatic. This led to the first religious war in ancient Turan. The composition of the participants in the battle for the belief, which took place on the southern outskirts of the Mary valley, was determined. On the basis of genetic data, the ethnic composition of the combatants was traced. It is concluded on the basis of the latest results of DNA studies of the inhabitants of the region that the Chionites, who, according to the conclusion of a number of leading historians, were Xiongnu, are actually proto-Xiongnu (Q). And this meant that since the Huns were Tengrians, the Chionites were early supporters of this belief. The religious war for belief was between the Tengrians and the Zoroastrians. It is concluded that Zarathushtra, who separated the new knowledge, came out of the depths of Tengrianism, observed some attributes of shamanism, was a Scythian by origin of an Asian branch of the R1a1a2b haplgroup.
FORMATION OF PATRIOTISM IN THE STUDENT ENVIRONMENT THROUGH THE INTERNET RESOURCES. (BASED ON THE SOCIOLOGICAL SURVEY OF STUDENTS OF NARXOZ UNIVERSITY)
Authors:   Narxoz University, Turyszhanova Roza , Zhaksybaeva Botagoz ,   Narxoz University
Published: November 2023

The novelty of the presented scientific article lies in the fact that the problem of the formation of patriotism in the Kazakh student environment has never been considered in the context of the possibilities of the Internet-environment as an agent of patriotic education. Patriotic impact of social networks and Internet resources is considered through a sociological survey of 2-3 year students of Narxoz University. The problem raised in the article is to reveal the possibilities of expanding the forms and methods of educating a patriotic personality through the use of Internet resources. Through a sociological survey, proposals are identified and recommendations are given for the formation of patriotic competence.
A new species of Tapinella Enderlein, 1908 (Insecta: Psocoptera) from French Guiana, North Amazon rainforest
Authors: Georgiev Dilian
Published: November 2023

A new species of Tapinella Enderlein, 1908 was described from French Guiana - T. montjoliensis n. sp. It was collected near Montjoly Town and Wayki Village. The species was found in a plantation and a village from dry banana (Musa sp.) leaves, and among river bank scrubs from dry leaves of various bushes.
Survey on Document Storage and Verification System using Blockchain Technology
Authors: Prathamesh Sinkar  , Gaurav Shende  , Sudhir Patil  , Mohit Pawar  , Prof. Supriya Jagtap
Published: November 2023

Blockchain technology promises to be hugely trending and empowering in financial domain computing applications. The digital economy is becoming an integral part of modern life. So as the use of the digital world increases there are more chances of decrease is the security level. So more the use of digitization more the frauds and less the security. In some cases of personal data, leakage has brought back into the focus the security issues with the different identity sharing mechanisms. A customer is expected to provide his identity for authentication by different agencies. So the KYC process deals with the identification of the user. And in turn, provides the required security. The KYC procedures which are used by the banks are completely dependent on the encryption which is slow and it can lead to the loss of customer details to other theirs party financial institutions. This system can be efficient by using Blockchain technology, which has the potential to automate a lot of manual processes and it is also resistant to hacks of any sort. The immutable blockchain block and its distributed ledger is the perfect complement to the process of KYC. With the addition of smart contacts, fraud detection can be automated. For KYC identity details storage we can make use of any types of KYC. So, the banks can develop a shared private blockchain within the bank premise and the same can be used for verifying the documents. This allows the user to get control of their sensitive documents and also makes it easier for banks to obtain the documents they need for compliance
تحليل البنيوية في الشعر "سلام عليكم" لأنيس شوشان (دراسة تحليلية نقدية)
Authors: Yudistira Wildan Yudistira
Published: November 2023

Semiotics is a branch of linguistics that is important to be studied by students of knowledge in the world. and in one of its theories is structuralism. However, in this study the researcher tried to use the semiotic structuralism theory using a literary criticism approach. the object of research is Arabic literary works, namely poetry by "Anies Syusyan", the purpose of this research to determine of intrinsic elements in the poem "salamun alaikum" by Anies Syusyan, as well as apply literary criticism about the advantages and disadvantages, as well as the quality of the poem "salamun alaikum" by Anies Syusyan. This research is a type of qualitative research, and researcher apply the documentation method in collecting data in this research. Researcher used a descriptive approach and literary criticism to analyze the data in this research. the results of this research are that the intrinsic elements contained in the poem "salamun alaikum" by Anies Syusyan is 6 of the totals. Researcher find the main idea or ideas, feelings or emotions, imagination, style of language, rhyme, and the interrelationships between intrinsic elements. Then, find two strengths and two weaknesses related to intrinsic elements, and determine the reasons to answer the quality of this poem related to intrinsic elements.
PERKEMBANGAN PONDOK PESANTREN BAITURRAHMAN PURBARATU DI BAWAH PIMPINAN KH KOMARUDIN ARSYAD PADA TAHUN 2001-2019
Authors: Prayoga Dian , Abdullah Asep
Published: November 2023

This research is motivated by developments during the leadership of K.H. Komarudin Arsyad, where there have been many changes in every field in a very short time, so that this Islamic boarding school is increasingly existing and has attracted many people to send their children to this Islamic boarding school, even though in Tasikmalaya City there are already several Islamic boarding schools whose systems and programs are the same as Islamic boarding schools. It can also be seen from the increasingly complete facilities. Departing from this idea, the author wants to know the secret behind the development of the Biturrahman cottage, which can occur very quickly and quickly. So the authors take several formulations of the problem including, how is the curriculum developed, how is the development of students and teachers, how is the impact on curriculum development and how is the development of facilities and infrastructure. With the following research objectives, to determine the development of the curriculum, to determine the development of students and teachers, to determine the impact of curriculum development and to determine the development of facilities and infrastructure. The methods used are heuristics, criticism, interpretation, and historiography. Data from this study were collected by interview techniques and some from literacy sources. The results of this study provide information related to the development process of the Baiturrahman Islamic boarding school, provide information regarding leadership, policies, and changes that make the Baiturrahman Islamic boarding school experience development.
KẾT QUẢ ĐIỀU TRỊ UNG THƯ BIỂU MÔ BUỒNG TRỨNG TÁI PHÁT NHẠY PLATINUM BẰNG PHÁC ĐỒ PACLITAXEL-CARBOPLATIN TẠI BỆNH VIỆN UNG BƯỚU NGHỆ AN
Authors: Vũ Thị Mỹ Linh , Phùng Thị Huyền , Nguyễn Văn Hiếu , Đỗ Anh Tú
Published: November 2023

Mục tiêu: Đánh giá kết quả điều trị phác đồ paclitaxel-carboplatin trên bệnh nhân ung thư buồng trứng tái phát nhạy platinum tại bệnh viện Ung bướu Nghệ An. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả, hồi cứu kết hợp tiến cứu trên. 44 bệnh nhân ung thư biểu mô buồng trứng (UTBMBT) tái phát nhạy platinum được điều trị phác đồ carboplatin kết hợp paclitaxel tại bệnh viện Ung Bướu Nghệ An từ 1/2017 đến tháng 9/2022. Kết quả: Một số đặc điểm chung của nhóm bệnh nhân: Tuổi trung bình mắc bệnh là 59,5 tuổi. Nhóm tuổi từ 50-69 là nhóm hay gặp nhất chiếm tỉ lệ 79,5%. Ung thư biểu mô thanh dịch độ cao là thể mô học phổ biến nhất với 84,1%. Có 29,5% số bệnh nhân tái phát trong vòng 6-12 tháng sau điều trị triệt căn và 70,5% tái phát trên 1 năm. Nồng độ CA12.5 tăng ở 86,4% số bệnh nhân. 43,2% số bệnh nhân được phẫu thuật công phá u tối đa khi tái phát. Kết quả điều trị: Tỷ lệ đáp ứng là 69,7% (23/33), 11 bệnh nhân đạt đáp ứng hoàn toàn chiếm 33,3%, 12 bệnh nhân đáp ứng một phần chiếm 36,4%. Trung vị thời gian sống thêm không tiến triển (PFS) là 11,1 tháng (CI 95%: 9,4 – 12,7); trung vị thời gian sống thêm toàn bộ (OS) là 30,1 tháng (CI 95%: 18,2 – 40,0). Tại thời điểm kết thúc nghiên cứu có 20 bệnh nhân còn sống chiếm 45,5%. Độc tính thường gặp là rụng tóc, độc tính thần kinh, hạ bạch cầu và tiểu cầu chủ yếu là độ 1-2, không có bệnh nhân nào tử vong do điều trị. Có 4 bệnh nhân ngừng điều trị phác đồ kết hợp paclitaxel-carboplatin do độc tính hóa trị, trong đó có 1 bệnh nhân shock phản vệ được điều trị thay thế carboplatin bằng cisplatin, 1 bệnh nhân dừng hóa chất do độc tính thần kinh độ 3 và được điều trị thay thế bằng gemcitabin,  2 bệnh nhân hạ tiểu cầu độ 3 và độ 4 chậm phục hồi được điều trị tiếp paclitaxel đơn chất. Kết luận: Phác đồ có Paclitaxel-Carboplatin là phác đồ có hiệu quả và độc tính chấp nhận được ở bệnh nhân ung thư biểu mô buồng trứng tái phát di căn nhạy platinum.
ĐẶC ĐIỂM LÂM SÀNG BỆNH NHÂN TRƯỢT ĐỐT SỐNG THẮT LƯNG CÙNG 1 TẦNG ĐƯỢC PHẪU THUẬT CỐ ĐỊNH CỘT SỐNG VÍT QUA DA VÀ HÀN XƯƠNG LIÊN THÂN ĐỐT QUA LỖ LIÊN HỢP SỬ DỤNG ỐNG NONG
Authors: Nguyễn Đức Hoàng , Hoàng Gia Du
Published: November 2023

Mục tiêu: Tiến hành nghiên cứu này với mục tiêu mô tả đặc điểm lâm sàng của người bệnh trượt đốt sống (TĐS) thắt lưng – cùng 1 tầng trước phẫu thuật MIS TLIF. Phương pháp: Nghiên cứu cắt ngang được thực hiện trên 35 người bệnh được chẩn đoán TĐS thắt lưng cùng 1 tầng, điều trị phẫu thuật trong thời gian (1/2021-12/2021) tại Khoa Chấn thương chỉnh hình và Cột sống - Bệnh viện Bạch Mai. Kết quả: Tuổi trung bình là 53.29 ± 12.21 (31 – 76). Triệu chứng lâm sàng cơ năng, điểm VAS lưng trung bình 5,2 ± 1,48, điểm VAS chân trung bình: 4,5 ± 1,24 điểm, điểm ODI trung bình 49,28±12,16 điểm. Triệu chứng lâm sàng thực thể, 20 người bệnh (57,1%) có dấu hiệu kích thích rễ thần kinh (Lasègue dương tính), 26 người bệnh (74,3%) có dấu hiệu co cứng cơ cạnh sống, 30 người bệnh (85,7%) có biểu hiện rối loạn cảm giác. Kết luận: Nghiên cứu cung cấp các thông tin về triệu chứng lâm sàng của người bệnh bị TĐS thắt lưng - cùng 1 tầng trước khi được phẫu thuật bằng cố định cột sống vít qua da và hàn xương  liên thân đốt qua lỗ liên hợp sử dụng ống nong.
TỈ LỆ HẠ ĐƯỜNG HUYẾT KHÔNG TRIỆU CHỨNG TRÊN NGƯỜI CAO TUỔI ĐÁI THÁO ĐƯỜNG TÍP 2 NẰM VIỆN TẠI BỆNH VIỆN QUẬN 2
Authors: Nguyễn Hồng Hà , Từ Kim Thanh , Lê Thái Thanh Thảo , Lê Thái Thanh Thảo , Nguyễn Thị Lệ
Published: November 2023

Đặt vấn đề: Nghiên cứu các yếu tố liên quan hạ đường huyết nặng trên người cao tuổi đái tháo đường típ 2 bằng hệ thống theo dõi đường huyết liên tục (CGMS) nhằm kiểm soát đường huyết tốt hơn và hạn chế những cơn hạ đường huyết không triệu chứng. Mục tiêu: Khảo sát yếu tố liên quan hạ đường huyết nặng trên người cao tuổi đái tháo đường típ 2 nằm viện tại Bệnh viện Quận 2 năm 2016-2018. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả, cắt ngang và tiến cứu trên 82 bệnh nhân người cao tuổi đái tháo đường típ 2 điều trị nội trú tại Bệnh viện Quận 2. Kết quả: Trong nghiên cứu của chúng tôi ghi nhận trong 45 bệnh nhân bị hạ đường huyết có 28 bệnh nhân bị hạ đường huyết nhẹ (62,2%), 17 bệnh nhân có cơn hạ đường huyết nặng (33,3%).Các yếu tố có liên quan đến hạ đường huyết nặng ở người cao tuổi đái tháo đường típ 2 bao gồm tiêm thêm Insulin nhanh (58,8%), bỏ ăn trưa (15,6%), bỏ ăn chiều (15,6%), tăng liều thuốc (82,4%). Kết luận: Các yếu tố liên quan đến bệnh nhân hạ đường huyết bao gồm tiêm thêm Insulin nhanh (58,8%), bỏ ăn trưa (15,6%), bỏ ăn chiều (15,6%), tăng liều thuốc (82,4%) (P<0,001). Yếu tố không liên quan đến hạ đường huyết nặng bao gồm tuổi, giới tính, thời gian mắc bệnh ĐTĐ, HbA1c, nhiễm trùng, tổng liều Insulin ngày, suy thận, suy gan.
MỘT SỐ ĐẶC ĐẶC HÌNH ẢNH CẮT LỚP VI TÍNH SỌ NÃO Ở BỆNH NHÂN CHẢY MÁU ĐỒI THỊ GIAI ĐOẠN CẤP TẠI BỆNH VIỆN BẠCH MAI
Authors: Trần Bảo Ngọc , Võ Hồng Khôi , Phan Văn Toàn
Published: November 2023

Mục tiêu: Mô tả đặc điểm lâm sàng và hình ảnh cắt lớp vi tính sọ não ở bệnh nhân chảy máu đồi thị giai đoạn cấp tại bệnh viện Bạch Mai năm 2022-2023. Đối tượng nghiên cứu: 140 bệnh nhân được Chẩn đoán chảy máu não trên lâm sàng bằng tiêu chuẩn chẩn đoán đột quỵ não của Tổ chức Y tế Thế giới (1989) trong thời gian từ tháng 6 - 2022 đến tháng 6 - 2023 tại Trung tâm thần kinh Bệnh viện Bạch Mai Bệnh viện Bạch Mai. Phương pháp nghiên cứu: Nghiên cứu mô tả loạt bệnh. Kết quả: Vị trí chảy máu của đồi thị ở vùng sau bên chiếm tỷ lệ cao nhất (42,86%), tiếp đến là 20% bệnh nhân chảy máu lan tỏa. Vị trí trước, trong và lưng đồi thị chiếm tỷ lệ tương đương nhau, lần lượt là 12,14%, 10,71% và 14,20%. Mức độ chảy máu nhu mô ở nhóm đối tượng nghiên cứu, đa số <30ml (81,43%), chỉ 5% bệnh nhân có mức độ chảy máu nhu mô từ 60ml trở lên. 77,86% bệnh nhân có mức độ đè đẩy đường giữa độ I, mức độ đè đẩy đường giữa độ III chỉ chiếm 3,57%. có 52,14% bệnh nhân không có chảy máu não thất; chảy máu một, hai, ba và bốn não thất lần lượt là 10,71%, 13,57%,11,43% và 12,14%. Có 71,43% bệnh nhân có mức độ chảy máu não thất theo thang điểm Graeb từ 0-4 điểm, chỉ có 12/140 bệnh nhân có điểm Graeb từ 9-12. 52,14% bệnh nhân có mức độ ứ giãn não thất 0 điểm Diringer, 12,14% bệnh nhân điểm từ 7-18, chỉ có 5,71% bệnh nhân từ 19-24 điểm. Kết luận: Phần lớn bệnh nhân chảy máu ở vùng sau bên đồi thị và đa số chảy máu < 30ml. Hầu hết các trường hợp chảy máu chỉ gây đè đẩy đường giữa mức độ I, với mức độ chảy máu não thất phần lớn là nhẹ. Trên 50% bệnh nhân không có ứ giãn não thất theo thang điểm Diringer.