Arterial Collaterals and Endovascular Treatment Effect in Acute Ischemic Stroke with Large Infarct: A Secondary Analysis of the TENSION Trial
Authors: Winkelmeier Laurens , Kniep Helge , Thomalla Götz , Bendszus Martin , Subtil Fabien , Bonekamp Susanne , Aamodt Anne Hege , Fuentes Blanca , Gizewski Elke R. , Hill Michael D. , Krajina Antonin , Pierot Laurent , Simonsen Claus Z. , Zeleňák Kamil , Blauenfeldt Rolf A. , Cheng Bastian , Denis Angélique , Deutschmann Hannes , Dorn Franziska , Gellissen Susanne , Gerber Johannes C. , Goyal Mayank , Haring Jozef , Herweh Christian , Hopf-Jensen Silke , Hua Vi Tuan , Jensen Märit , Kastrup Andreas , Keil Christiane Fee , Klepanec Andrej , Kurča Egon , Mikkelsen Ronni , Möhlenbruch Markus , Müller-Hülsbeck Stefan , Münnich Nico , Pagano Paolo , Papanagiotou Panagiotis , Petzold Gabor C. , Pham Mirko , Puetz Volker , Raupach Jan , Reimann Gernot , Ringleb Peter Arthur , Schell Maximilian , Schlemm Eckhard , Schönenberger Silvia , Tennøe Bjørn , Ulfert Christian , Vališ Kateřina , Vítková Eva , Vollherbst Dominik F. , Wick Wolfgang , Fiehler Jens , Flottmann Fabian ,   on behalf of the TENSION Investigators, Gizewski Elke R. , Grams Astrid E. , Dazinger Florian , Janjic Tanja , Gindlhuber Karin , Knoflach Michael , Willeit Johannes , Boehme Christian , Kiechl Stefan , Glodny Bernhard , Volderauer Karoline , Mayer-Süß Lukas , Galijasevic Malik , Trenkler Johannes , Meckel Stephan , Gruber Joachim , Sonnberger Michael , Bach Elke , Lenzenweger Eva , Schwarzenhofer Daniel , Deutschmann Hannes , Augustin Michael , Wießpeiner Ulrike , Portugaller Rupert Horst , Kalmar Peter , Magyar Marton , Hassler Eva Maria , Seifert-Held Thomas , Niederkorn Kurt , Gattringer Thomas , Pichler Alexander , Fandler-Höfler Simon , Rohler Siegfried , Thaler Daniela , Schmid Florian , Horner Susanne , Killer-Oberpfalzer Monika , Müller-Thies-Broussalis Erasmia , Mutzenbach Sebastian , Pikija Slaven , Hecker Constantin , Al-Schameri Rahman , Lunzer Manuel , Kral Michael , Weymayr Friedrich , Bubel Nele , Ganser Bernhard , Leitner Ursula , Hacker-Ivan Floriana , Moser Tobias , Kreidenhuber Rudolf , Delalic Asima , Leitinger Markus , Johannes Pfaff , Volna Kamila , Otto Ferdinand , Mauritz Matthias , Jedlitschka Angela , Hill Michael D. , Goyal Mayank , Ryckborst Karla J , Krajina Antonín , Chovanec Vendelín , Raupach Jan , Vítková Eva , Medek Oldřich , Renc Ondřej , Matyáš David , Vališ Kateřina , Křivka Tomáš , Suškevič Igor , Vaníček Jiří , Vojtíšek Bohuslav , Mikulík Robert , Jakubíček Stanislava , Eliášová Ilona , Weiss Viktor , Goldemund David , Strýček Ondřej , Búřil Jiří , Haršány Michal , Doležalová Irena , Roubec Martin , Hurtíková Eva , Bar Michal , Volný Ondřej , Jonszta Tomáš , Čábal Martin , Novobilský Richard , Brodová Petra , Čurdová Nina , Kovář Martin , Panský Michal , Mencl Pavel , Šnajdrová Alena , Roztočilová Milada , Simonsen Claus Ziegler , Andersen Grethe , Schmitz Marie Louise , Damgaard Dorte , Hjort Niels , Poulsen Marika , Diedrichsen Tove , DupontHougaard Kristina , VonWeitzel-Mudersbach Poul , AnkerlundBlaufeldt Rolf , Karabegovic Sanja , ZachoSpeiser Lasse , HougaardSoerensen Leif , BayThomsen Rikke , Jensen Schiela , Modrau Boris , Figlewski Krystian , Falkesgaard Maiken , HjortJensen Nina , PlougmannPovlsen Jan , Delekta Agnieszka , Simonsen Maria Theresa , Oder Joanna , Rudnicka Svetlana , Al-Kuzae Fadha Elawi , Pierot Laurent , Pagano Paolo , Hua Vi Tuan , Clarençon Fréderic , Sourour Nader , Shotar Eimad , Lenck Stéphanie , Premat Kévin , Allard Julien , Rosso Charlotte , Crozier Sophie , Leder Sara , Leger Anne , Vassilev Christine , Delorme Stephen , Baronnet Flore , Wittwer Aymeric , Ferré Jean-Christophe , Alias Quentin , Chabert Emmanuel , Ferrier Anna , Bendszus Martin , Möhlenbruch Markus A. , Seker Fatih , Ulfert Christian , Mohr Alexander , Breckwoldt Michael , Neuberger Ulf , Vollherbst Dominik , Herweh Christian , Jesser Jessica , Jestaedt Leonie , Kronlage Moritz , Schwarz Daniel , Ringleb Peter Arthur , Purrucker Jan , Schönenberger Silvia , Brekenfeld Casper , Thomalla Götz , Fiehler Jens , Hoppe Julia , Cheng Bastian , Deb-Chatterji Milani , Gellißen Susanne , Schlemm Eckhard , Weber Werner , Fischer Sebastian , Weber Anushe , Oldag Andreas , Rohde Stefan , Adamczewski Olaf , Breyer Tobias , Hellstern Victoria , Henkes Hans , Maegerlein Christian , Wunderlich Silke , Liebig Thomas , Dorn Franziska , Brem Christian , Forbig Robert , Trumm Christoph , Kellert Lars , Wollenweber Frank , du Mesnil de Rochemont Richard , Wagner Marlies , You Se-Jong , Berkefeld Joachim , Keil Fee , Rai Frau Heike , Bohmann Ferdinand , Pfeilschifter Waltraud , Schäfer Jan-Hendrik , Maurer Gabriele , Förch Christian , Schmidt Christoph , Rauch Maximilian , Breuer Stella , Polkowski Christoph , Seiler Alexander , Polomac Nenad , Spitzer Daniel , Schaller-Paule Martin , Kestner Roxane-Isabelle , Boss Erendira Gabriela , Brandhofe Annemarie , Wenger-Alakmeh Katharina , Trendafilov Petar , Steidl Eike , Kurka Natalia , Gelhard Sarah , Lauer Monika , Scholtz Jan-Erik , Hoelter Maya , Reitz Sarah , Keeba Natalia , Gruber Katharina , Kohlhase Konstantin , Charisse Daniel , Patrick Samp , Dorn Franziska , Lehnen Nils , Solymosi Lazlo , Paech Daniel , Petzold Gabor C. , Bode Felix J. , Meissner Julius N. , Ebrahimi Taraneh , Stösser Sebastian , Weller Johannes M. , Theisen Sara , Becker Sandra , Müller-Hülsbeck Stefan , Hopf-Jensen Silke , Petersen Inga , Merkle Andrea , Keese Petra , Mesche Birte , Preiß Michael , Leißner Maximilian , Marques Leonardo , Holtmannspoetter Markus , Kohler Sabine , Lange Rüdiger , Voit-Höhne Heinz-Leonhard , Eff Florian , Städt Michael , Galczak Romana , Lamprecht Susanne , Krause Lars Udo , Beer Sylvia , Petersen Martina , Lowens Stephan , Kellinghaus Christoph , Strickmann Sarah , Behme Daniel , Görtler Michael , Paukisch Harald , Diamandis Elie , Ergawy Mostafa , Zubel Seraphine , Maximilian Thormann , Neumann Jens , Barleben Maria , Assmann Anne , Katja Hopp , Karen Kollo , Borggrefe Jan , Mönninghoff Christoph , Kuschnerow Michael , Kröger Jan Robert , Röttcher Thomas , Reimann Georg , Schneider Claus , Schellinger Peter , Mücke Ramona , Retzlaff Jasmin , Michalski Dominik , Hoffmann Karl-Titus , Pelz Johann , Gawlitza Matthias , Lachmund Rita , Boxhammer Elfi , Aamodt Anne Hege , Kefalaykos Christina , Tennøe Bjørn , Skjelland Mona , Enriquez Brian , Ryan Stephen , Tunold Jon-Anders , Hallerstig Erika , Søyland Jogrim , Sandvik Simen , Prestsæter Sjur , Sømark Jesper , Argren Maria , Skagen Karolina , Tveit Lars , Fromm Annette , Wathle Gaute Kjellevold , Kaalaas Størda Anne Margrethe , Zelenak Kamil , VORČÁK Martin , SÝKORA Jan , KRKOŠKA Adam , SIVÁK Jozef , SORŠÁK Jakub , KURČA Egon , ZELEŇÁKOVÁ Jana , NOSÁL’ Vladimír , Klepanec Andrej , Haring Jozef , Krastev Georgi , Cisár Juraj , Daniš Martin , Haršány Ján , Bavúzová Xénia , Ondrejkovič Marián , Gimeno Blanca Fuentes , Álvarez Alberto , Barrios Andrés , Fernández Andrés , de Celis Elena , Ruiz Gerardo , Rodríguez Jorge , Casado Laura , de Leciñana M Alonso , Navia Pedro , Rigual Ricardo , Hernández Victoria , Prieto-Pérez Rocio , Rivera-Bengoa Carlota , Psychogios Marios , Tsogkas Ioannis , Brehm Alex , Nguyễn Anh , Nussbaum Lukas , Giannakakis Michail Panagiotis , Ntoulias Nikos , Sporns Peter , Fischer Urs , Damaskinos Michele 
Published: February 2025

In patients with large ischemic stroke, thrombectomy within 12 hours after onset was superior to best medical treatment in reducing 90-day functional disability irrespective of the collateral status on single-phase CT angiography images.