bluuebunny/crossref_metadata_2025 huggingface dataset:
Lightweight multi-agent framework for a cluster-based wireless sensor network
Authors: Bano Shahzadi , Afghan Syeda A. , Jokhio Sana H. , Talpur Shahnawaz , Jokhio Imran A.
Published: May 2018

Sensor applications and wireless sensor networks (WSNs) are becoming a part of our everyday life. A number of network arrangements are used in WSN. In this paper, we focus on the cluster based network to help identify the issues associated with communication within such networks. We present a lightweight multi-agent routing framework for a cluster based WSN to resolve some issues associated with such networks. By using state- of-art protocol in a unique combination and categorizing cluster layers, we take full advantage of the properties of the selected protocols. The simulation results illustrate that the proposed method is light-weight in terms of energy consumption by the sensor nodes communicating information within a cluster based network. Nevertheless, high network throughput and robust data communication are also achieved.
O caso biográfico de "Guardiola: confidencial" (2015): a impossibilidade de dizer tudo
Authors: Gama Gabriel Canuto Nogueira da
Published: May 2018

Resenha da biografia Guardiola: confidencial (2015), de Martí Perarnau.
Prasugrel versus ticagrelor in patients with Acute Coronary syndrome treated with percutaneous coronary intervention
Authors: Jamwal Naveen , Tripathi Shiv Shanker
Published: May 2018

Background: No association studies for the efficacy and safety of ticagrelor vs. prasugrel have been published in India. Aim of the study was to compare the safety and efficacy of Prasugrel versus Ticagrelor in Patients with Acute Coronary Syndrome Treated with Percutaneous Coronary Intervention.Methods: This retrospective study was designed to compare the efficacy and safety of prasugrel and ticagrelor in acute coronary syndromes (ACS) with percutaneous coronary intervention (PCI). A total of 480 patients were studied who had been prescribed either prasugrel or ticagrelor during PCI. Primary end-point was defined as death, re-infarction, urgent target vessel revascularization, serious bleeding requiring transfusion.Results: Primary endpoint was different between the groups receiving prasugrel and ticagrelor (1.2% and 4.0%, respectively; OR (95% CI) 0.38 (0.098; 1.43); P=0.065). Difference was found in the need for urgenttarget vessel revascularization which was significantly lower in the prasugrel group.Rest of the parameters were almost similar with no significant difference.Conclusions: This study comparing prasugrel and ticagrelor shows that Prasugrel is more effective than Ticagrelor in lowering ischemic events in the acute coronary syndromes treated with PCI strategy, especially incidence of stent thrombosis. These observations need further analysis and follow-up.
Is serum glutathione level in combination with serum PSA useful for early detection of prostatic carcinoma? A local study of Iraq
Authors: Mohammad Ehab Jasim
Published: May 2018

Background: Prostate cancer is the most common cancer and the second leading cause of cancer-related death among men of western countries. The aim of this study is to develop non-invasive diagnostic tools for the early detection of prostate cancer (PCa) through detection of low level of Serum reduced Glutathione (GSH).Methods: Serum samples from men being evaluated for PCa were analyzed for reduced Glutathione (GSH) level. The results were compared with the prostate needle biopsy findings and (PSA) level combined with Digital Rectal Examination (DRE). Samples were obtained from 59 cases including 18 controls.Results: The maximum sensitivity of the test was observed in the first category of confirmed cases with 93.33% turs positive detected with low GSH. Among those highly suspected Ca prostate there was 87.5% true positive test and 12.5% false negative results. Among those in grey zone where PSA between is 4 and 10, and DRE is suggestive, the proportion of true positive was 50%.Conclusions: These results demonstrate that serum reduced Glutathione (GSH) level is helpful in patient with definite carcinoma. This test could be useful in augmenting current PCa diagnostic procedures. For example, the examination test for reduced Glutathione (GSH) level with an elevated prostate- specific antigen level might be used in predicting which patients will have negative biopsies and may be used as treatment modality for PCa.
La Bienal de Música Contemporánea de 1964
Authors: San Llorente Pardo Inés
Published: May 2018

La celebración en Madrid de la Bienal de Música Contemporánea en 1964 supuso para sus organizadores romper con el aislamiento al que había estado sometida la música de vanguardia española: por un lado, ésta tomó contacto con las últimas obras y procedimientos compositivos europeos; por otro, se dio a conocer en los ambientes internacionales, que tantos años le habían estado vedados. Los cambios artísticos y culturales en la España franquista hicieron posible la celebración de un festival de estas características, patrocinado por el Estado y con la música contemporánea como protagonista. Pero esta iniciativa, que debía prolongarse en el tiempo con sucesivas ediciones, se frustró desde el momento en que la música se mezcló con la política. Apoyándose en fuentes hemerográficas y archivísticas, este artículo analiza el desarrollo de la Bienal y profundiza en las consecuencias artísticas, musicales y políticas que se derivaron de dicho evento.
El villancico en la Catedral de Jaca durante el reinado de Felipe V (1700-1746): recepción y evolución del nuevo estilo
Authors: Escuer Salcedo Sara
Published: May 2018

Resumen de tesis doctoral
LANGUAGE AND DISCOURSE IN ENVIRONMENTAL EDUCATION RESEARCH IN BRAZIL: A STUDY OF THE EARTE PLATFORM
Authors: Silva Rosana Louro Ferreira , Fernandes José Artur Barroso
Published: May 2018

Following on from discussions on the ‘languages and discourses’ subtheme at the 13 th Invitational Seminar on Environmental Education Research, this exploratory study in document analysis discusses various aspects of academic production on language and discourse in the area of Environmental Education (EE). The study centers on the analysis of thesis and dissertation abstracts contained in the EArte Project database, an open access digital repository of state of the art EE research in Brazil. Results suggest that the term ‘language’ appears only infrequently and then usually in relation to different forms of expression, whereas the term ‘discourse’ is far more pervasive, present in the titles of studies on a highly diverse range of research themes.
Luki dochodowe w systemie pomocy mieszkaniowej dla niezamożnych gospodarstw domowych w Polsce. Wnioski z badań krajowych
Authors: Rataj Zuzanna
Published: May 2018

System socjalnej pomocy mieszkaniowej w Polsce skierowany jest do ubogich i bardzo ubogich gospodarstw domowych. Pomija on grupę gospodarstw niezamożnych, uzyskujących dochody niekwalifikujące ich do uzyskania lokali z gminy, a także niewystarczające, aby uzyskać mieszkanie na rynku w oparciu o finansowanie kredytem bankowym. Odpowiedzią na zgłaszane potrzeby mieszkaniowe tej grupy miały być zasoby towarzystw budownictwa społecznego. Badania prowadzone w latach 2015–2016 ukazały luki w systemie pomocy mieszkaniowej w Polsce. Kryteria dochodowe uprawniające do najmu poszczególnych typów mieszkań – z zasobów gminy i TBS‑ów – ustalone są w taki sposób, że między jednymi a drugimi powstaje luka dochodowa. W konsekwencji gospodarstwa uzyskujące dochody mieszczące się w tym przedziale nie mają możliwości otrzymania pomocy w formie lokalu mieszkalnego. Pozostaje im najem z puli rynkowej – o wyższych czynszach, z nie zawsze uregulowaną formą najmu. Ponadto kryteria dochodowe uprawniające do najmu lokalu komunalnego i z TBS‑ów są wysokie, sięgają nawet poziomu zdolności kredytowej gospodarstw domowych. Czy zatem rozwiązania w zakresie pomocy mieszkaniowej są dostosowane do zgłaszanych potrzeb i spełniają swoje funkcje? W artykule autorka próbuje odpowiedzieć na to pytanie i inne, powiązane z nim, a także przybliża zaobserwowane problemy. Badania prowadzone były w ramach projektu pt. „Społeczne budownictwo mieszkaniowe i jego rola w zaspokajaniu potrzeb mieszkaniowych niezamożnych gospodarstw domowych w Polsce” finansowanego ze środków Narodowego Centrum Nauki (2014/13/N/HS4/02100).
Wpływ cykli koniunkturalnych na działalność innowacyjną przedsiębiorstw w krajach Unii Europejskiej
Authors: Kijek Arkadiusz
Published: May 2018

Różnokierunkowe powiązania między działaniami innowacyjnymi przedsiębiorstw a fazami cykli koniunkturalnych wywołują problemy z jednoznacznym określeniem charakteru tej zależności. Głównym celem artykułu jest ocena wpływu faz cyklu koniunkturalnego na nakłady oraz na efekty działań innowacyjnych podmiotów gospodarczych. Dlatego przeprowadzono badanie aktywności innowacyjnej firm w krajach UE i w Norwegii w latach 2002–2014, zarówno w okresach recesji, jak i w czasach ożywienia gospodarczego. Empiryczna weryfikacja teoretycznych założeń potwierdziła złożony charakter relacji między działalnością innowacyjną przedsiębiorstw a cyklami koniunkturalnymi.
Etyka gospodarcza jako refleksja nad jakościowym potencjałem działalności ekonomicznej
Authors: Wiśniewski Jakub Bożydar
Published: May 2018

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Teorie dóbr publicznych i zrównoważonego rozwoju w myśli filozoficznej Johna Locke’a
Authors: Rutkowska Anna
Published: May 2018

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Ameliorative efficacy of citrus oil in aflatoxin induced changes in lymphoid organs in broilers-A pathomorphological evaluation
Authors: Senthilkumar D , Rao Suguna , Satyanarayana M L , Kumar P G Pradeep , Anitha N
Published: May 2018

A total of 160 day-old broiler chicks were divided randomly into four groups with two replicates of 20 birds each. The birds were fed with basal diet, basal diet with CFO, basal diet with aflatoxin, basal diet with CFO and AF. Serum globulin level was significantly reduced in birds fed with AF only on 14th day of treatment. Microscopically, mild degree of congestion, histiocytosis and cellular sparcity of the periarteriolar lymphoid component were observed in the spleen whereas lymphoid cell depletion in thymus and bursal follicles were prominent. Additionally, thymus revealed moderate degree of congestion and haemorrhages in widened medulla, histiocytosis and degeneration of Hassall’s corpuscles. In CFO and AF fed birds, the extent and degree of lesions were lesser with compact arrangement of lymphoid cell with widening of cortex was observed mainly during later days of experiment. There was widening of lymphoid component of caecal tonsils up to mucosal layer in CFO fed birds.
Association of polymorphism at intron 2 of FABP3 Gene with milk production traits in Sahiwal and Karan Fries cattle
Authors: Yadav Alok Kumar , Mukherjee Anupama , Kumar Suchit
Published: May 2018

PCR-RFLP analysis of PCR products were carried out using Aci I / SSi I for 100 Sahiwal and 115 Karan Fries cattle. In Sahiwal cattle and Karan Fries cattle, 438bp has three genotypes AA (438), AB (438+299+139 bp) and BB (299+139 bp). In Sahiwal cattle these genotypes are highly significant for FL305DPY but in Karan Fries cattle these genotypes are highly significant for FL305DMY, FLTMY, FL305DFY and FL305DPY. In Sahiwal cattle, mean ± SE of AA genotype for FL305DMY, FLTMY, FL305DFY, FL305DSNFY, FL305DPY were 1809.90 ± 15.7 kg, 2029.4 ± 15.6 kg, 99.90 ± 0.66 kg, 154.87 ± 0.17 kg and 44.81 ± 0.06 kg, respectively and for AB genotype were 1800.76 ± 9.48 kg, 1993.99 ± 9.42 kg, 100.54 ± 0.39 kg, 154.79 ± 0.10 kg, 43.99 ± 0.04 kg, respectively and for BB genotype were 1830.0 ± 14.10 kg, 2032.80 ± 14.0 kg, 100.24 ± 0.59 kg, 155.11 ± 0.15 kg, 42.98 ± 0.05 kg, respectively. Heterozygous AB genotype was found to be superior for, FL305DFY trait. AA genotype was significantly superior for FL305DPY traits whereas BB genotype was found to be superior for FL305DMY, FLTMY, FL305DSNFY. In Karan Fries cattle, the mean ± SE of AA genotype for FL305DMY, FLTMY, FL305DFY, FL305DSNFY, FL305DPY were 3442.17 ± 8.39 kg, 4461.93 ± 8.39 kg, 124.96 ± 7.20 kg, 277.35 ± 0.08 kg and 112.51 ± 0.08 kg, respectively and for AB genotype were 3572.69 ± 5.93 kg, 4592.45 ± 5.93 kg, 140.17 ± 5.09 kg, 278.60 ± 0.06 kg, 113.91 ± 0.05 kg, respectively and for BB genotypes were 3502.41 ± 9.19 kg, 4522.17 ± 9.19 kg, 136.91 ± 7.89 kg, 277.93 ± 0.09 kg, 113.19 ± 0.08 kg, respectively.
Punicalagin is beneficial for spermatogenesis in male New Zealand White rabbits
Authors: Gulay Ozlem Yildiz , Gulay Mehmet Sukru
Published: May 2018

Taking into account that punicalagin (PUN) is a very powerful antioxidant; the current study evaluated the potential positive effects of oral PUN on spermatologic parameters of male New Zealand White rabbits. A total of 24 male bucks was housed individually and trained for semen collection. After the training for 2 wk, rabbits were assigned into 4 groups and received daily gavages of 0, 1, 2, and 10 mg/kg PUN in tap water for 9 wk. Semen was collected weekly from each rabbit and samples at d 1 and 63 of the experiment were analyzed separately. Initial values (ejaculate volume, ejaculate weight, ejaculate pH, sperm concentration, percent progressive motility, and seminal plasma protein levels) tested at d 1 were similar among the groups. There were also no differences in ejaculate volume, ejaculate weight, ejaculate pH and seminal plasma protein concentrations at the end of the experiment. Libido and reproductive organ weights were not affected by the treatments.However, sperm concentrations (P Less then 0.01) and percent progressive motility (P Less then 0.04) were significantly improved for bucks in 2 and 10 mg/kg PUN groups. Thus, the current study suggested that as low as 2 mg/kg/day PUN can be beneficial for spermatogenesis and motility in male rabbits.
EVIDENCIAÇÃO DAS CARACTERÍSTICAS BÁSICAS RECOMENDADAS PELO COSO (2004) PARA A GESTÃO DE RISCOS EM AMBIENTES DE CONTROLE NO RELATÓRIO DA ADMINISTRAÇÃO DE EMPRESAS BRASILEIRAS COM ADRs
Authors: Zonatto Vinícius Costa da Silva , Beuren Ilse Maria
Published: May 2018

O estudo objetiva verificar se as características básicas recomendadas pelo COSO (2004) para o estabelecimento de um ambiente de controle estão sendo amplamente divulgadas conforme estabelece a Lei Sarbanes-Oxley no relatório da administração de empresas brasileiras com emissão de ADRs. Para tanto, realizou-se pesquisa descritiva por meio de análise documental. A amostra da pesquisa compreendeu 28 empresas brasileiras com emissão de American Depositary Receipt. No relatório da administração de 2007 buscou-se identificar as características básicas do modelo COSO (2004) evidenciadas pelas empresas pesquisadas. Os resultados da pesquisa mostram que todos os componentes ou ambientes do modelo COSO (2004) foram identificados no relatório da administração de 2007 das empresas pesquisadas, mas nem todas as características básicas contidas nos respectivos componentes ou ambientes foram evidenciadas. Conclui-se que nem todas as características básicas recomendadas pelo COSO (2004) para o estabelecimento de um ambiente de controle estão sendo amplamente divulgadas conforme estabelece a Lei Sarbanes-Oxley no relatório da administração das empresas pesquisadas.
TRANSMISSÃO INTERGERACIONAL: UMA CONTRIBUIÇÃO AO ESTUDO DO COMPORTAMENTO DO CONSUMIDOR DE ALIMENTOS
Authors: Spanhol Caroline Pauletto , Lima Filho Dario de Oliveira , Lima Maria de Fátima Evangelista Mendonça
Published: May 2018

A escolha dos alimentos tem sido estudada por várias áreas do conhecimento, entre elas destacando-se o Marketing, aEconomia, a Psicologia, a Nutrição, a Medicina, a Sociologia e a Antropologia. A área do Marketing e da Economia trata da escolha de produtos, utilizando modelos na maioriaquantitativo-econométricos, ao contrário deste estudo, queutiliza a metodologia qualitativa, baseando-se na teoria da intergeracionalidade, por considerar a escolha, sobretudo ade alimentos, um fenômeno complexo. Para tanto, foram realizadas entrevistas semiestruturadas com dez mães residentesna cidade de Campo Grande/MS. A técnica utilizadapara o estudo dos dados é a análise de conteúdo. Os resultados apontam que, além das restrições estruturais, existe apresença do fenômeno da intergeracionalidade como fator importante na escolha de alimentos. Sendo assim, pode-se dizer que no processo de escolha de alimentos está presentea herança simbólica recebida, principalmente da mãe, influenciando as atuais escolhas dos indivíduos por alimentos.
O DESEMPENHO DOS POSTOS DE ATENDIMENTO AO TRABALHADOR NA PERSPECTIVA DOS EMPREGADORES DA REGIÃO BRAGANTINA (SP)
Authors: Antunes de Souza Dércia , Gil Antonio Carlos
Published: May 2018

Esta pesquisa tem como objetivo analisar a percepção dosempregadores acerca do desempenho do Posto de Atendimentoao Trabalhador (PAT) das cidades de Bragança Paulista,Atibaia e Itatiba. Consiste num levantamento de camporealizado com uma amostra de 100 clientes empresas.Conclui-se que os PATs são identificados com a intermediaçãode mão de obra pouco qualificada, já que a maioriados candidatos que os procuram são pessoas de baixa rendae baixo nível de escolaridade. Esse fato pode estar indicandodeficiência dos PATs, que não são reconhecidos pelasempresas como entidades adequadas para o suprimento desuas necessidades de pessoal nos mais diversos níveis. Maspode também estar indicando a relevância social dos serviçosdos PATs, já que para grandes contingentes de trabalhadores,eles constituem o principal, senão o único elo com omercado de trabalho.
La metáfora como pauta narrativa en "Arenas movedizas": procedimientos de producción de sentido
Authors: Rodríguez Adriana Azucena
Published: May 2018

En este artículo propongo que algunos textos de "Arenas movedizas" de Octavio Paz poseen una estructura narrativa reconocida por el mismo autor; están compuestos a partir de una metáfora que posee una función narrativa, es decir, de la Interpretación de ésta depende el sentido que se le dará a los acontecimientos relatados, pues la metáfora opera bajo un sistema de relaciones que enriquecen el significado del texto y de ella misma. La metáfora aparece como una figura nodal, al Igual que los conceptos de narrativa y surrealismo, para la interpretación de algunosrelatos de esta obra.
Amapolas deshojadas o el horror de la maternidad. "El último verano" de Amparo Dávila
Authors: Gutiérrez Piña Claudia L.
Published: May 2018

"El último verano", texto perteneciente al tercer volumen de cuentos de Amparo Dávila, Árboles petrificados (1977), es un cuidadoso relato con una de las estructuras más acendradas de la simbólica femenina: la maternidad. La fuerza del texto radica en el tratamiento que otorga a la simbólica femenina, en un ejercicio crítico que retoma la figura de la madre para llevarla a su quiebro, por medio del desmontaje de los símbolos que le sostienen, para articular, gradualmente, a la maternidad como el agente del horror en el relato. Esto artículo analiza el sustrato simbólico del cuento, que convoca el carácter ambivalente del arquetipo de la madre, donde se unen los opuestos creación-destrucción, vida-muerte.
Una patria sin pasaporte. Octavio Paz y Francia
Authors: Bradu Fabienne
Published: May 2018

El texto reconstruye la relación de Octavio Paz con Francia desde su infancia hasta su muerte. Se muestra cómo Francia era un imán para los intelectuales de la generación del poeta mexicano y cómo su pertenencia a ese país se solidificó a raíz de su estancia de diez años en París, en calidad de diplomático. Octavio Paz no fue considerado como un objeto de estudio, como muchos otros creadores latinoamericanos, sino como un sujeto con el que los intelectuales franceses dialogaban directamente. El repaso termina con la labor de traductor de la poesía francesa moderna que Octavio Paz cumplió a lo largo de su vida.
Historia de las primeras traducciones de novelas mexicanas (1928-1947)
Authors: Rosenzweig Gabriel
Published: May 2018

Al igual que las novelas latinoamericanas en su conjunto, las novelas mexicanas so comenzaron a traducir a finales de los años veinte del siglo pasado. No obstante la relevancia que revisten las traducciones para conocer los inicios de la difusión de la literatura mexicana en ámbitos lingüísticos distintos al del español, su historia aún no se ha escrito. Este artículo ofrece un panorama de cómo se desarrolló el proceso. Da cuenta de que las primeras traducciones no fueron promovidas por los autores o editores originales, sino por terceros; se hicieron con base en contratos que suscribieron los editores con los autores, ya fuera de manera directa o a través do intermediarios; en general, no generaron beneficios económicos y, en contraste con lo que se ha sostenido, sólo en algunos casos las traducciones al francés estuvieron en el origen de las traducciones a otras lenguas europeas.
Pengaruh Mindset, Kepemimpinan, dan Nilai Keluarga terhadap Budaya Organisasi Perusahaan Keluarga [Influence of Mindset, Leadership, and Family Values on the Organizational Culture of Family Firms]
Authors: Bella Maria , Maichal Maichal
Published: May 2018

This research aims to find out how significant the mindset, leadership, and family values influence the organizational culture of family firms. This research is a quantitative research which uses questionnaires as the data collection method. The population of this research is the students of University of Ciputra who attend the Family Business class in the odd semester of 2016 Entrepreneurship subject. There are 59 respondents’ data which fit as samples of this research and the data is processed by using the Partial Least Square (PLS) analysis method. The result of this research shows that (1) mindset significantly affects leadership, (2) leadership does not significantly affect the organizational culture of family firms, (3) mindset significantly affects family values, (4) family values significantly affect the organizational culture of family firms, (5) family values do not significantly affect leadership, (6) mindset does not significantly affect the organizational culture of family firms, and (7) the organizational culture of family firms can be formed by the leader’s mindset which are reflected through the family values believed and applied within the companies.

Bahasa Indonesia Abstrak: Penelitian ini bertujuan untuk mengetahui seberapa signifikan mindset, kepemimpinan, dan nilai keluarga berpengaruh terhadap budaya organisasi perusahaan keluarga. Penelitian ini merupakan penelitian kuantitatif yang menggunakan kuesioner sebagai metode pengumpulan data. Populasi pada penelitian ini adalah mahasiswa Universitas Ciputra yang tergabung dalam kelas Family Business pada mata kuliah Entrepreneurship semester ganjil 2016. Terdapat 59 data responden yang dinyatakan layak untuk digunakan sebagai sampel penelitian dan data diolah dengan menggunakan metode analisis Partial Least Square (PLS). Hasil dari penelitian ini menunjukkan bahwa (1) mindset berpengaruh secara signifikan terhadap kepemimpinan, (2) kepemimpinan tidak berpengaruh secara signifikan terhadap budaya organisasi perusahaan keluarga, (3) mindset berpengaruh secara signifikan terhadap nilai keluarga, (4) nilai keluarga berpengaruh secara signifikan terhadap budaya organisasi perusahaan keluarga, (5) nilai keluarga tidak berpengaruh secara signifikan terhadap kepemimpinan, (6) mindset tidak berpengaruh secara signifikan terhadap budaya organisasi perusahaan keluarga, (6) kepemimpinan tidak berpengaruh secara signifikan terhadap budaya organisasi perusahaan keluarga, dan (7) budaya organisasi perusahaan keluarga dapat dibentuk oleh mindset pemimpin yang tercerminkan melalui nilai keluarga yang diyakini dan ditanamkan di dalam perusahaan.
High Performance Work System and Organizational Citizenship Behavior in Multinational Companies in Vietnam: the Mediation Effect of Career Success
Authors: Vu Giang Thi Huong
Published: May 2018

In this study, the relationship between high performance work system (HPWS) and organizational citizenship behavior (OCB) in multinational corporations (MNCs) in Vietnam, a fast-developing country with highly economic growth in Asia, was investigated. Besides, the underlying mechanism of this relationship was also explored. From the social exchange approach, an underlying mediated mechanism of career success in the relationship between HPWS and OCB was hypothesized. Data collected from individual employees working in multinational companies in Vietnam was used to test the hypotheses. The research findings supported the partial mediating role of career success in the positive relationship between HPWS and OCB. In addition, research implications as well as suggestions for future research were also presented.

 

Bahasa Indonesia Abstrak: Dalam studi ini, hubungan antara high performance work system (HPWS) dan organizational citizenship behavior (OCB) di multinational corporations (MNC) di Vietnam, negara cepat berkembang dengan pertumbuhan ekonomi yang sangat tinggi di Asia, ditelliti. Selain itu, mekanisme yang mendasari hubungan ini juga dieksplorasi. Dari pendekatan pertukaran sosial, mekanisme mediasi yang dimediasi dari kesuksesan karir dalam hubungan antara HPWS dan OCB dihipotesiskan. Data yang dikumpulkan dari masing-masing karyawan yang bekerja di perusahaan multinasional di Vietnam digunakan untuk menguji hipotesis. Temuan penelitian mendukung peran mediasi parsial dari kesuksesan karir dalam hubungan positif antara HPWS dan OCB. Selain itu, implikasi penelitian serta saran untuk penelitian masa depan juga disajikan.
Novos movimentos sociais e o direito ao transporte coletivo no Brasil
Authors: Duarte Rebeca Barreto , Silva Renata Maldonado da
Published: May 2018

Este estudo tem o objetivo de situar o Movimento Passe Livre (MPL) no estudo dos chamados novos movimentos sociais. Para isso discutimos, inicialmente, o modelo de política de transporte adotada no Brasil e a luta pelo direito ao transporte coletivo, dando destaque ao MPL. Este se autodenomina um movimento social autônomo, horizontal, independente, apartidário (porém não antipartidário), que luta por um transporte público gratuito para toda a população. Posteriormente, trazemos a discussão dos novos movimentos sociais, tomando como referência principalmente Bihr (2010) e Touraine (1988). Por fim, realizamos uma relação entre o Movimento Passe Livre e o proposto pelos autores supracitados acerca dos novos movimentos sociais.
As leis do período militar e seus reflexos sobre o trabalho e o trabalhador
Authors: Castilho Maria Augusta , Oliveira Monizzi Mábile Garcia , Borges Pedro Pereira
Published: May 2018

O estudo resulta da análise dos processos trabalhistas do Tribunal Regional do Trabalho - MS dos anos de 1964 a 1969, vinculado ao projeto, “Análise dos processos trabalhistas do Tribunal Regional do Trabalho- MS (1962-1984)”, estabelecido via convênio com o TRT da 24ª Região MS, junto com a Universidade Católica Dom Bosco. A pesquisa objetiva contribuir para a conservação da memória do trabalho e do trabalhador no Brasil, em especial no estado de MT/MS, no período de 1964 a 1969. A metodologia foi pautada no método dedutivo via análise documental e embasamento teórico, voltado para consultas/leituras bibliográficas em livros, jornais, artigos sobre a memória do trabalho e das leis trabalhistas brasileiras. Foram feitos levantamentos das leis trabalhistas criadas ou adaptadas durante o período analisado, época em que o país vivia um processo de ditadura militar e análises de diversos processos sobre as situações dos trabalhadores no período analisado.
Qualidade de vida, sedentarismo e o impacto econômico do diabético, no sistema municipal de saúde
Authors: Grzelczak Marcos Tadeu , Souza William Cordeiro de , Lima Valderi Abreu de , Mascarenhas Luis Paulo Gomes
Published: May 2018

O presente estudo teve por objetivo investigar a possível relação entre prática de atividade física (AF), qualidade de vida (QV) e custo medicamentoso na população diabética cadastrada pelo HIPERDIA, no Sistema Público de Saúde de Porto União, SC. Os resultados demonstraram não haver diferença estatística nas variáveis antropométricas, IMC, custo medicamento e QV entre o grupo ativo (G1) e o grupo inativo (G2) diabéticos, cabe mencionar que o Delta (∆) de variação foi maior em todos os valores para o grupo inativo (G2), em que o percentual ficou na casa de 50%. Sendo assim, foi verificado que os diabéticos que apresentaram maiores índices de AF, necessitam de menos medicação em relação aos sedentários.
A Arquidiocese de Cuiabá ontem e hoje: perspectivas pastorais
Authors: Barbosa Neto João Dos Santos
Published: May 2018

Esta pesquisa visa proceder na apresentação histórica, social e pastoral da Arquidiocese de Cuiabá, a partir da época em que era uma capelania da Arquidiocese de Rio de Janeiro até o seu estado atual. É relevante o desenvolvimento progressivo das práticas religiosas do povo cuiabano e a consolidação da presença da Igreja Católica, que determina, por meio de seu calendário religioso, o ritmo da vida do povo. Toda a história, devidamente documentada, é narrada através dos olhares dos bispos e arcebispos que conseguiram obter respostas significativas ao próprio tempo e colaboraram na formação e identificação dos cidadãos de Cuiabá em um povo com tradições e valores cristãos. Nessa linha, seguem as atuais ações pastorais da Arquidiocese; com uma linguagem moderna, esforçam-se para continuar sendo essa luz divina capaz de iluminar o coração de seu povo em um tempo de crise e de dificuldades.
La formación de jóvenes científicos
Authors: Arévalo Zelada Jorge
Published: May 2018

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Growth Hormone (GH) Administration Increases the Metabolic Activity of the left Hippocampus in an Elder Patient with Cognitive Disorders
Authors: Devesa Jesús , Núñez Iria , Agra Carlos , Bejarano Alejandro , Devesa Pablo
Published: May 2018

1) Background: We analyzed, by PET-SCAN, how growth hormone (GH) might act on the brain of a not GH-deficient elder woman who suspected that she was developing Alzheimer's disease; 2) Methods: After performing a first psychometric study (TAVEC verbal learning test), the metabolic activity of brain structures related to cognition, memory and behavior was analyzed by 18-F Fluorodeoxyglucose PET-SCAN. The patient was then treated with GH (0.4 mg/day) during three weeks and the last day under this treatment a new PET-SCAN was carried out. One month after commencing the treatment with GH a new TAVEC test was performed; 3) Results: GH administration normalized the cognitive deficits observed in the first cognitive test and significantly (p < 0.025) increased (Voxel-Based Morphometry) the metabolic activity in the left hippocampus, left amygdala and left parahippocampus, but also in practically all brain cortical areas; 4) Conclusions: This is the first study in which the effects of GH on the brain have been visualized in images. Our data confirm the positive effects of this hormone on cognition and memories; although they do not allow us to conclude whether GH administration may be useful in the early stages of Alzheimer's disease, they seem to be promising.
Use of decision Tables to Simulate Management in Ecohydrological Models
Authors: Arnold Jeffrey G. , Bieger Katrin , White Michael J. , Srinivasan Raghavan , Dunbar John A. , Allen Peter M.
Published: May 2018

Decision tables have been used for many years in data processing and business applications to simulate complex rule sets. Several computer languages have been developed based on rule systems and they are easily programmed in several current languages. Land management and river-reservoir models simulate complex land management operations and reservoir management in highly regulated river systems. Decision tables are a precise yet compact way to model the rule sets and corresponding actions found in these models. In this study, we discuss the suitability of decision tables to simulate management in the river basin scale Soil and Water Assessment Tool (SWAT+) model. Decision tables are developed to simulate automated irrigation and reservoir releases. A simple auto irrigation application of decision tables was developed using plant water stress as a condition for irrigating corn in Texas. Sensitivity of the water stress trigger and irrigation application amounts were shown on soil moisture and corn yields. In addition, the Grapevine Reservoir near Dallas, Texas was used to illustrate the use of decision tables to simulate reservoir releases. The releases were conditioned on reservoir volumes and flood season. The release rules as implemented by the decision table realistically simulated flood releases as evidenced by a daily NSE (Nash-Sutcliffe Efficiency) of 0.52 and a percent bias of -1.1%. Using decision tables to simulate management in land, river and reservoir models was shown to have several advantages over current approaches including: 1) mature technology with considerable literature and applications, 2) ability to accurately represent complex, real world decision making, 3) code that is efficient, modular and easy to maintain, and 4) tables that are easy to maintain, support, and modify.
A Case Study of Smart Grid Station in Guri Branch Office of KEPCO
Authors: Whang Jaehong , Hwang Woohyun , Yoo Yeuntae , Jang Gilsoo
Published: May 2018

Climate change and global warming are becoming important problems around the globe. To prevent these environmental problems, many countries try to reduce the emissions of greenhouse gases (GHG) and manage the consumption of energy. In Korea, Korea Electric Power Corporation (KEPCO) has introduced Smart Grid (SG) technologies to its branch office in 2014. This was the first demonstration of smart grid on a building called Smart Grid Station. This paper treats the achievements of the Smart Grid Station (SGS) by its early target in three aspects. The things are peak reduction, power consumption reduction and electricity fee saving. The authors analyzed the achievements by comparing the data of 2015 with the data of 2014. Through the evaluation, the authors studied the case, proved the advantages of SGS, and suggested the requirements to improve and the direction to go of the system.
Polyphenols from Tamarix nilotica: LC–ESI-MSn Profiling and In-Vivo Antifibrotic Activity
Authors: Sekkien Ahmed , Swilam Noha , Ebada Sherif , Esmat Ahmed , Elkhatib Ahmed H. , Linscheid Michael W. , Singab Abdel Nasser
Published: May 2018

Tamarix nilotica (Ehrenb.) Bunge (Tamaricaceae), an indigenous plant to the Middle East region, is well-known as a medicinal plant for treating many human ailments. The current study aimed at exploring the polyphenols profile of T.nilotica alcohol soluble fraction of aqueous extract, assessing its in-vivo antifibrotic activity and the possible underlying mechanism, to unravel the impact of quantitative difference of sulphated polyphenols content on the antifibrotic activity of T.nilotca grown in two different habitats. Polyphenols profiling of T. nilotica extracts was performed using HPLC-HRESI-QTOF-MS-MS. The major polyphenol components included sulphated flavonoids, phenolic acids and free aglycones. The antifibrotic activity was evaluated through carbon tetrachloride-induced liver fibrosis in rats. Biochemical evaluations revealed that both fractions ameliorated the increased levels of hepatic aminotransferases, lipid peroxidation, hydroxyproline, α-smooth muscle actin (α-SMA), tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2) and nuclear factor kappa B (NF-κB). Moreover, both fractions reduced catalase activity (CAT) and enhanced hepatic glutathione (GSH) content. Histopathological imaging undoubtedly confirmed such results. In conclusion, T. nilotica polyphenols rich fraction exhibited potential antifibrotic activity in rats. Significant alterations in GSH levels were recorded based on sulphated polyphenol metabolites content.
Direct Observation of Hydrangea Blue-Complex Composed of 3-O-glucosyldelphinidin, Al3+ and 5-O-acylquinic Acid by ESI-Mass Spectrometry
Authors: Ito Takaaki , Oyama Kin-ichi , Yoshida Kumi
Published: May 2018

The blue sepal color of hydrangea is due to a metal complex anthocyanin composed of 3-O-glucosyldelphinidin (1) and an aluminum ion with the co-pigments 5-O-caffeoylquinic acid (2) and/or 5-O-p-coumaroylquinic acid (3). The three components, namely, anthocyanin, Al3+ and 5-O-acylquinic acids, are essential for blue color development, but the complex is unstable and only exists in aqueous solution. Furthermore, the complex did not give analyzable NMR spectra or crystals. Therefore, many trials to determine the detailed chemical structure of the hydrangea-blue complex have failed to date. Instead, via experiments mixing 1, Al3+ and 2 or 3 in a buffered solution at pH 4.0, we obtained the same blue solution derived from the sepals. However, the ratio was not stoichiometric but fluctuated. To determine the composition of the complex, we tried direct observation of the molecular ion of the complex using electrospray-ionization mass spectrometry. In a very low-concentration buffer solution (2.0 mM) at pH 4.0, we reproduced the hydrangea-blue color by mixing 1, 2 and Al3+ in ratios of 1:1:1, 1:2:1 and 1:3:1. All solution gave the same molecular ion peak at m/z = 843, indicating that the blue solution has a ratio of 1:1:1 for the complex. By using 3, the observed mass number was m/z = 827 and the ratio of 1, 3 and Al3+ was also 1:1:1. A mixture of 1, 3-O-caffeoylquinic acid (4) and Al3+ did not give any blue color but instead was purple, and the intensity of the molecular ion peak at m/z = 843 was very low. These results strongly indicate that the hydrangea blue-complex is composed of a ratio of 1:1:1 for 1, Al3+ and 2 or 3.
Effect of low concentrations of dissolved oxygen on the activity of denitrifying methanotrophic bacteria
Authors: Kampman Christel , Piai Laura , Temmink Hardy , Hendrickx Tim L. G. , Zeeman Grietje , Buisman Cees J. N.
Published: May 2018

Chemical energy can be recovered from municipal wastewater as biogas through anaerobic treatment. Effluent from direct anaerobic wastewater treatment at low temperatures, however, still contains ammonium and considerable amounts of dissolved methane. After nitritation, methane can be used as electron donor for denitrification by the anaerobic bacterium ‘Candidatus Methylomirabilis oxyfera’. It was shown that in the presence of 0.7% O2, denitrifying methanotrophic activity slightly increased and returned to its original level after oxygen had been removed. At 1.1% O2, methane consumption rate increased 118%, nitrite consumption rate increased 58%. After removal of oxygen, methane consumption rate fully recovered, and nitrite consumption rate returned to 88%. Therefore, traces of oxygen that bacteria are likely to be exposed to in wastewater treatment are not expected to negatively affect the denitrifying methanotrophic process. 2.0% O2 inhibited denitrifying activity. Nitrite consumption rate decreased 60% and did not recover after removal of oxygen. No clear effect on methane consumption was observed. Further studies should evaluate if intermittent addition of oxygen results in increased growth rates of the slow-growing ‘Candidatus Methylomirabilis oxyfera’.
Perspectives and New Aspects of Metalloproteinases’ Inhibitors in the Therapy of CNS Disorders: From Chemistry to Medicine
Authors: Boguszewska-Czubara Anna , Budzynska Barbara , Skalicka-Wozniak Krystyna , Kurzepa Jacek
Published: May 2018

:

Matrix metalloproteinases (MMPs) play a key role in remodeling of the extracellular
matrix (ECM) and, at the same time, influence cell differentiation, migration, proliferation,
and survival. Their importance in a variety of human diseases including cancer, rheumatoid
arthritis, pulmonary emphysema and fibrotic disorders has been known for many years but
special attention should be paid on the role of MMPs in the central nervous system (CNS)
disorders.

:

Till now, there are not many well documented physiological MMP target proteins in the brain
but only some pathological ones. Numerous neurodegenerative diseases are a consequence of
or result in disturbed remodeling of brain ECM, therefore proper action of MMPs as well as
control of their activity may play crucial roles in the development of these diseases.

:

In the present review, we discuss the role of metalloproteinase inhibitors, from the wellknown
natural endogenous tissue inhibitors of metalloproteinases (TIMPs) to the exogenous
synthetic ones like (4-phenoxyphenylsulfonyl)methylthiirane (SB-3CT), tetracyclines, batimastat
(BB-94) and FN-439. As the MMP-TIMP system has been well described in physiological
development as well as in pathological conditions mainly in neoplastic diseases, the
knowledge about the enzymatic system in mammalian brain tissue still remains poorly understood
in this context. Therefore, we focus on MMPs inhibition in the context of the
physiological function of the adult brain as well as pathological conditions including neurodegenerative
diseases, brain injuries, and others.
Cyclooxygenase-2 Inhibitors as a Therapeutic Target in Inflammatory Diseases
Authors: Ferrer Miguel D. , Busquets-Cortés Carla , Capó Xavier , Tejada Silvia , Tur Josep A. , Pons Antoni , Sureda Antoni
Published: May 2018

Inflammation plays a crucial role in the development of many complex diseases and disorders including autoimmune diseases, metabolic syndrome, neurodegenerative diseases, and cardiovascular pathologies. Prostaglandins play a regulatory role in inflammation. Cyclooxygenases are the main mediators of inflammation by catalyzing the initial step of arachidonic acid metabolism and prostaglandin synthesis. The differential expression of the constitutive isoform COX-1 and the inducible isoform COX-2, and the finding that COX-1 is the major form expressed in the gastrointestinal tract, lead to the search for COX-2-selective inhibitors as anti-inflammatory agents that might diminish the gastrointestinal side effects of traditional non-steroidal anti-inflammatory drugs (NSAIDs). COX-2 isoform is expressed predominantly in inflammatory cells and decidedly upregulated in chronic and acute inflammations, becoming a critical target for many pharmacological inhibitors. COX-2 selective inhibitors happen to show equivalent efficacy with that of conventional NSAIDs, but they have reduced gastrointestinal side effects. This review would elucidate the most recent findings on selective COX-2 inhibition and their relevance to human pathology, concretely in inflammatory pathologies characterized by a prolonged pro-inflammatory status, including autoimmune diseases, metabolic syndrome, obesity, atherosclerosis, neurodegenerative diseases, chronic obstructive pulmonary disease, arthritis, chronic inflammatory bowel disease and cardiovascular pathologies.
Clinical and Pharmacologic Features of Monoclonal Antibodies and Checkpoint Blockade Therapy in Multiple Myeloma
Authors: D’Agostino Mattia , Gazzera Giulia , Cetani Giusy , Bringhen Sara , Boccadoro Mario , Gay Francesca
Published: May 2018

Background:

Survival of multiple myeloma patients has considerably improved in the last decades thanks to the introduction of many new drugs, including immunomodulatory agents, proteasome inhibitors and, more recently, monoclonal antibodies.

Methods:

We analyzed the most recent literature focusing on the clinical and pharmacologic aspects of monoclonal antibody-based therapies in multiple myeloma, including monoclonal antibodies directed against plasma cell antigens, as well as checkpoint blockade therapy directed against immune inhibitory molecules, used as single agents or in combination therapy.

Results:

Anti-CD38 monoclonal antibodies including daratumumab, isatuximab and MOR202 have shown outstanding results in relapsed and/or refractory multiple myeloma patients. The addition of daratumumab to bortezomib-dexamethasone or lenalidomidedexamethasone substantially improved patients’ outcome in this patient population. The anti- SLAMF7 molecule elotuzumab in combination with lenalidomide-dexamethasone showed to be superior to lenalidomide-dexamethasone alone, without adding meaningful toxicity. Checkpoint blockade therapy in combination with immunomodulatory agents produced objective responses in more than 50% of treated patients. However, this combination was also associated with an increase in toxicity and a thorough safety evaluation is currently ongoing.

Conclusion:

Monoclonal antibodies are reshaping the standard of care for multiple myeloma and ongoing trials will help physicians to optimize their use in order to further improve patients’ outcome.
Subtypes of Antiphospholipid Antibodies in Neurologic Disorders: An Observational Study
Authors: Sahebari Maryam , Rastin Maryam , Boostani Reza , Forughipour Mohsen , Hashemzadeh Kamila , Sadeghi Samira H.
Published: May 2018

Background and Objectives: Concomitant neurologic manifestations and positive antiphospholipid
antibodies (APAs) have been investigated in different manners. The present study
aimed to investigate the association between neurologic manifestations and APAs.

Materials and Methods: This cross-sectional descriptive study was conducted on 100 consecutive
patients with selected neurological manifestations and at least one positive APAs within the age
range of 20-50 years, referred to the Rheumatic Diseases Research Center from the Northeast Central
Neurology Department of Iran during August 2012 to March 2014.

Results:

According to the results, 89% of the participants were persistently positive for APAs,
including lupus anticoagulant, IgG anticardiolipin (aCL), IgM aCL, IgG β-2 glycoprotein 1 (β2-
GP1), and IgM β2-GP1, observed in 16%, 41%, 42%, 17%, and 15% of the patients, respectively.
Furthermore, 10% of the patients had concomitant lupus manifestations, and 37% of them showed
anti-DNA. The IgG and IgM aCL were the most prevalent antibodies. Cerebral vascular accident
(33%), retinal artery/vein occlusion (21%), and seizure (20%) were the most frequent presentations
among the patients. In addition, the patients with multiple sclerosis (composing 3% of the subjects)
were 100% positive for IgG and IgM aCL, as well as lupus anticoagulant. In addition, IgM anti-β2-
GP1 was 100% positive in optic neuritis patients (composing 5% of the subjects) and was significantly
associated with this neurologic disorder. IgM anti-β2-GP1 was also prevalent in the cases
with Guillain-Barré syndrome. The most prevalent persistently positive antibody in the patients
with cerebrovascular accident was IgM aCL.

Conclusion:

The findings of this study revealed some associations between the subtypes of APAs
and incidence of neurologic disorders. However, the exact correlation between those symptoms and
APAs needs further investigations.
Web-Delivered Multimedia Training Materials for the Self-Collection of Dried Blood Spots: A Formative Project (Preprint)
Authors: Allen Alicia M , Lundeen Kim , Murphy Sharon E , Spector Logan , Harlow Bernard L
Published: May 2018

BACKGROUND

The use of dried blood spots (DBS) in biomedical research has been increasing as an objective measure for variables that are typically plagued by self-report, such as smoking status and medication adherence. The development of training materials for the self-collection of DBS that can be delivered through the Web would allow for broader use of this methodology.

OBJECTIVE

The objective of this study was to evaluate the acceptability and feasibility of the self-collection of DBS using newly developed multimedia training materials that were delivered through the Web. We also aimed to assess the usability of the collected DBS samples.

METHODS

We recruited participants through Facebook advertising for two distinct studies. The first study evaluated the acceptability of our newly developed DBS training materials, while the second assessed the implementation of this protocol into a larger Web-based study.

RESULTS

In the first study, participants (N=115) were aged, on average, 26.1 (SD 6.4) years. Training materials were acceptable (113/115, 98.2%, of participants were willing to collect DBS again) and produced usable samples (110/115, 95.7%, collected DBS were usable). In the second study, response rate was 25.0% (41/164), with responders being significantly younger than nonresponders (20.3 [SD 0.2] vs 22.0 [SD 0.4]; P<.001), and 92% (31/41) of collected DBS samples were usable by the laboratory.

CONCLUSIONS

Overall, while the protocol is acceptable, feasible, and produced usable samples, additional work is needed to improve response rates.