bluuebunny/crossref_metadata_2025 huggingface dataset:
Pattern of dysglycemia among Nigerian adult patients with vitiligo: a 10-year retrospective study
Authors: Amadi Collins , Odum Ehimen P.
Published: March 2018

Background: The prevalence of dysglycemia among adult patients with vitiligo is higher than the general population. However, data is scarce in our region regarding this hypothesis. This study was to define the pattern of dysglycemia in adult Nigerian patients with vitiligo.Methods: The study was conducted retrospectively among vitiligo patients who visited the University of Port Harcourt Teaching Hospital between 1st January 2007 and 31st December 2016. The laboratory characteristics of this patients were evaluated. Data collected irrespective of vitiligo variant were age, sex, and fasting plasma glucose concentrations.  Shapiro-Wilk test, descriptive statistics, chi-square test, Fisher’s exact test, and two-sample t-test were used for analysis. The level of p < 0.05 was considered statistically significant.Results: There were a total of 160 vitiligo patients consisting of 55 (34.4%) males and 105 (65.6%) females. The overall patients mean age was  35±1.9 years (range 19 -61 years). The mean fasting plasma glucose concentration was 5.3±1.1mmol/l.  Impaired fasting plasma glucose was detected in 41(26.6%) subjects with female dominance (female 61.0% versus male 39.0%).  Diabetes mellitus was documented in 6 (3.8%) subjects with no sex difference (female 50% versus male 50%).Conclusions: Dysglycemia is frequent in vitiligo patients. Screening for dysglycemia should be incorporated into the management protocol of patients with vitiligo.
Renin angiotensin system and pulmonary hemodynamics in chronic obstructive pulmonary disease
Authors: Chauhan Preeti , Chetiwal Rajesh
Published: March 2018

Background: Pulmonary hypertension in chronic obstructive pulmonary disease (COPD) due to chronic alveolar hypoxia is probably the main contributor to the pathogenesis of pulmonary hypertension in COPD.  Angiotensin II is a potent vasoconstrictor in renin angiotensin aldosterone system (RAAS), it has been shown to promote growth response in vascular smooth muscle cell contributing towards pulmonary hypertension. So, the Echocardiographicaliy measured MPAP and its correlation with RAAS in patients of COPD was evaluated.Methods: A prospective observational study was done in 32 patients with COPD and 10 age matched healthy, non-smoker subject included as controls. Stable patients requiring no change in their medication in the previous four weeks and not having had an acute exacerbation in that period were included. MPAP was calculated. Measurement of Ang II and aldosterone was done.Results: Thirty-two cases of COPD, meeting inclusion criteria were enrolled comprising of 32 males and the mean age of patients ±2sd was (55.6 ±16.8), while mean age of controls ± 2sd was 49.60 ±5.56. Arterial blood gas analysis, PaO2 was ranged from (mean±2sd 75.44±12.1), PaCo2 ranged from (mean ±2sd 41.36±3.79) and SpO2 ranged from (mean±2sd 94.03 2±.74). Mean ±2sd of plasma Ang II in COPD cases was (4.9±3.8) ng/dl, significantly higher in comparison with controls (p < 0.001). Mean ±2sd of plasma ACE activity was (51.12±26.9) in COPD. Mean ±2sd of plasma aldosterone was (182.35±364.2) in COPD cases with significant (p<0.01). The MPAP in COPD cases was (mean±2sd 34.53±7.70).Conclusions: Use of Doppler has the advantage of being noninvasive and has been shown to be extremely reproducible in evaluation of MPAP and CO. The increased level of Ang II with increase MPAP in the present study would suggest that this may be a suitable model for investigating effects of novel vasodilator drugs for the treatment of pulmonary hypertension developed due to COPD.
Rise of human devastation syndrome in Syria
Authors: Ahmed Syed Roshaan , Mahmood Syed Uzair , Waheed Haema
Published: March 2018

The Syria Civil War, which started in 2011, has killed 400,000 people. It has forced more than 11 million people to suffer and has caused not only the people to migrate but also to be displaced within their own country. The war has brought only misery in the lives of Syrians as the damage has only focused on residents of the region in combat. The children have faced the worst, losing their parents, siblings or even friends to violence, suffering physical and psychological trauma. Out of the 11 million and more people who have suffered, 4.9 million Syrians are refugees and 6.1 million have displaced within Syria, out of which half of those affected are children.The end result of the continued Syria Civil War is that those who have managed to survive have been severely damaged both physically and psychologically, disturbing their interpersonal, psychosocial, physical and mental health. The incidence of post traumatic stress disorder (PTSD) increases in such a situation, which tends to affect the lives of the Syrian people permanently.
Online medical consultation: a review
Authors: Singh Ajeet Pal , Joshi Hari Shanker , Singh Arun , Agarwal Medhavi , Kaur Palveen
Published: March 2018

The Internet has been a steady source of medical data previously; it has just as of late been utilized for online private patient-doctor consultations. As of late, the market has seen a surge in applications providing healthcare services on the go. An online consultation has secured a foothold in the market and individuals are opening up to the likelihood of substituting a visit to a physical facility with an online option. This study reports a review of the literature on online medical consultation from various databases as well as various surveys and reports published. As per published work/reports/surveys, the various factors which led to a sudden surge in the online medical consultation are the convenience, shift in disease patterns, cost-effective, privacy and second opinion.
Awareness and practices related to dengue fever among rural high school students: a cross sectional study
Authors: Ramaiah Radha , Jayarama Srividya
Published: March 2018

Background: Dengue is an acute viral infection with potential fatal complications and one of the leading cause of childhood Deaths in our country. Being a major international public health concern, the main method to control or prevent its transmission is to combat vector mosquitoes for which awareness about available preventive methods can play a major role. The objective of the study was to study the awareness and practices of the school students with respect to dengue.Methods: A cross-sectional study was conducted among 369 high school students using pretested structured questionnaire and analysis was done with open Epi and Microsoft excel.Results: The fact that dengue is caused by mosquito bite was known to 96% students respectively. 43% students knew that female mosquito bites and spread diseases. Only 21% knew that they are caused by Aedes mosquito. 47% knew that it breeds in clean stagnant water and 49% knew that it bites during day. Only 50-60% students took personal protective measures against mosquito bites and check for breeding of mosquitoes. 95% students felt that prevention of these diseases should be taught in schools.Conclusions: awareness among students is an important factor for preventing dengue in the community. Findings of the study will be helpful to make strategies for students to enhance knowledge on these diseases. Government should utilize methods of mass communication for educating about mosquito borne diseases.
Incidence of vitamin D deficiency in pediatric neurology outpatient department of a tertiary care hospital
Authors: Karnavat Purva Keni , Hegde Anaita Udwadia , Nabi Fazal
Published: March 2018

Background: Pediatric neurology outpatient populations are a vulnerable subgroup for vitamin D deficiency. The aim was to study the incidence of vitamin D deficiency in pediatric neurology patients by studying relevant biochemical profile and to assess the contributory factors for the same.Methods: A hospital based cross sectional study was conducted at a tertiary care setup in Mumbai between 2011 and 2012. A total of 284 children aged 0.5-18 years, attending pediatric neurology OPD were enrolled. Statistical analysis was carried out with SPSS version 17.0 and included descriptive statistics; Chi squared and unpaired t-tests to investigate significance of proposed predictors for vitamin D status.Results: 89.1% of the children were deficient in vitamin D levels (≤30 ng/ml); out of these 11% were severely deficient. Factors significantly associated with vitamin D deficiency were increasing age (p=0.034), absence of intake of calcium supplements (p=0.00) and upper socio-economic class (p=0.001). Low serum calcium levels (p=0.01) and high PTH levels (p=0.00) were associated significantly. Prevalence was similar in children with higher BMI as compared to lower BMI. Duration of AEDs rather than number of drugs was more associated with deficiency.Conclusions: A high prevalence of vitamin D inadequacy in noted in pediatric neurology patients.
Prevalence and factors affecting tobacco use among urban adolescents in Bhilai city, central India
Authors: Nayak Snehamayee , Mishra Abhisek
Published: March 2018

Background: Most tobacco users initiate their smoking habit quite young, upto 10 yrs of age. The physiological and psychological changes in this phase of life with an inquisitiveness to become autonomous enhance their vulnerability for addiction, tobacco use and dependency. its use during adolescence are likely to continue the use into adulthood and contribute to the 90 per cent of premature deaths among tobacco users. In this context the prevalence, patterns and correlates of tobacco use are studied among adolescent of urban slums of Bhilai city, Chhattisgarh India.Methods: Total 172 adolescents within the age group of 10-19 yrs, across 30 slums of Bhilai city are taken by cluster random sampling. They have been administered a self-administered questionnaire incorporating standardized instruments.Results: Of the 172 study respondents, the overall lifetime prevalence of tobacco use is 25 per cent (18% boys and 7% girls). Among users category the prevalence of tobacco use increased from 2.3 per cent at 10-14 yrs to 58.2 per cent at 18-19 yr. The mean age of onset of tobacco use was 14.8±3.1 yr. The prevalence is higher among subjects belong to lower socio-economic status and those with part-time jobs. Tobacco users had significantly higher rates of use of alcohol (90%) than tobacco non users (7.8%). They are having any form of stress in family (55% vs. 31.5%), more severe psychological distress (65 vs. 25.6%) and a sense of hopelessness (40 vs. 19%).Conclusions: The prevalence of tobacco use in adolescents reported in this study is relatively higher than those reported from other Indian States. However, it correlates with multiple socio-demographic and familial predicting factors suggesting a need to promote health and holistic interventions to prevent adolescent tobacco use.
Study on compliance of anti-hypertensive drugs among hypertensive patients in urban health centre of a tertiary care hospital
Authors: Gurupatham Dhanasekar , Shanmugam Jeevithan , Felix John William , L. M. Sandhya
Published: March 2018

Background: Hypertension is a chronic condition of concern due to its role in the cardiovascular complications. Poor compliance is assumed to be an important explanation for inadequate blood pressure control, convincing evidence for the same is lacking. This study was undertaken to provide such evidence, so that corrective measures can be recommended to attain better BP control. The aims and objectives of the study were to study compliance pattern and side effects of anti-hypertensive drugs among the known hypertensive patients; to study role of different factors that influence the compliance rate such as age, number of medications, frequency and follow-up visits of antihypertensive medication.Methods: A total of 207 hypertensive patients were identified from the family folders maintained in the Urban Health Centre, RMMCH and included in the investigation. During first visits, socio-demographic, drug intake history was taken. Follow up was done every two months and thus totally six visits were completed.Results: Socio demographic factors like age, marital status, literacy, occupation and income have no role on the compliance status. Sex has significant association with the compliance level (86.1%), where males have 93.4% and females 82.7% compliance (p<0.05). BMI, exercise, smoking and alcohol, Type of the drug, doses frequency, combination therapy and regularity in refilling the prescription, have no association with compliance status. Frequency of clinical visits has significant association with compliance (visit fortnightly, monthly and occasionally is 94.1%, 85.1% and 75% respectively) p<0.05. Significant improvement (73.1%) improvement in compliance in the VI visit is seen among non-compliers from I visit (p<0.001).Conclusions: Simple once a day regimen and visits of the health provider improves the compliance and good blood pressure control.
A study of vaccination delay among under-five attendees at an immunisation clinic in a rural area of Goa
Authors: Noronha Elvira , Shah Hemangini K.
Published: March 2018

Background: Vaccination has effectively shown to reduce mortality and morbidity due to vaccine-preventable diseases. However, these diseases are still responsible for majority of childhood deaths worldwide especially in the developing countries. It should be realized that with hesitance or delaying vaccinations, the period that the child at risk increases. Hence, the following study was conducted.Methods: A cross sectional study was carried out among 251 under-five immunization clinic attendees at an immunization clinic conducted at the Rural Health and Training Centre in Goa for a period of two months. Parents of the under-five children were interviewed and vaccination dates were obtained from health cards and vaccination delay was assessed.Results: Out of the total 251 study participants, 43.4% were males and 56.6% were females; 36.7% belonged to <2 years of age whereas 63.3% belonged to >2 years of age group. The education of the mothers and fathers of under five children, upto secondary education was 50.6% and 55.4% respectively and 31.5% of the study participants belonged to high socio-economic status. It was observed that 31% of the study participants (n=78) had a vaccination delay whereas 69% (n=173) of them were vaccinated on time. The reasons for delay in vaccination included unawareness, forgetfulness, sickness and migration. A statistically significant association was found between age, working status, socio-economic status and vaccination delay (p<0.05).Conclusions: Strategies must be evolved to educate the parents in the study area to have greater awareness regarding the immunization programmes.
Utilization of quality assessments in improving adolescent reproductive and sexual health services in rural block of Maharashtra, India
Authors: Chauhan Sanjay L. , Joshi Beena N. , Raina Neena , Kulkarni Ragini N.
Published: March 2018

Background: The present study was conducted with an objective to evaluate the quality of ARSH services; assess if these services met the National Standards of care and to utilize periodic program improvement recommendations through the WHO - quality assessment (QA) tools. Quality of ARSH services at twenty public health facilities in a rural block of a state in India were assessed using WHO-QA tools with a pre-test post-test interrupted time series design.Methods: Seven standards of care addressing provision of quality ARSH services (Standard I-IV); demand generation for these services (V-VI); and management information system (Standard VII) were assessed using WHO-QA tools for five years (2009-2014). Data analysis was done using Excel scoring template developed jointly with WHO. Scores were given for each standard and to each facility.Results: Periodic interventions resulted in improving the average facility score from 27% to 83% and overall standards score from 28% to 81% at baseline and endline survey respectively. The average scores for Standards I-IV improved from 43% 86%; for standards V–VI from 3% to 66% while for standard VII from 16% to 92% at baseline and endline survey respectively.Conclusions: Appropriate QA and periodic evidence-informed program inputs improved the quality and utilization of ARSH services. However, community outreach activities continued to be challenging. The assessment demonstrated feasibility and usefulness of using the WHO-QA tools to monitor and improve the quality of ARSH services.
Regeneração Óssea Guiada Em Região Estética - Revisão De Literatura
Authors: Tomm Alvin , Mezzomo Ricardo Josué
Published: March 2018

Introdução: a Regeneração Óssea Guiada tem por objetivo a reconstrução do rebordo alveolar utilizando membranas. Este procedimento é indicado quando não existe tecido ósseo suficiente para a colocação de implantes ou nos casos em que a estética é necessária. Objetivo: verificar, por meio de revisão de literatura, a previsibilidade da Regeneração Óssea Guiada em região estética. Métodos: a presente revisão de literatura contou com a pesquisa em artigos cientificos, indexados na base de dados Pubmed, buscando as seguintes palavras-chave: Esthetics, Guided bone regeneration (GBR), Dental Implant, Long-term, Follow-up. Conclusão: a literatura mostra que a técnica de regeneração é viável e apresenta longevidade ao longo do tempo.
Conhecimento de mães sobre saúde bucal na infância
Authors: Gislon Luciane Campos , Bottan Elisabete Rabaldo , Staimbach Camila Oselame , Rafaeli Carolyne
Published: March 2018

Objetivo: Avaliar o conhecimento sobre saúde bucal de um grupo de mães de diferentes condições socioeconômicas. Métodos: O estudo descritivo transversal teve como população-alvo as mães de crianças matriculadas na rede municipal de ensino básico, em um município do oeste de Santa Catarina. O instrumento de coleta de dados foi um questionário. Para a classificação socioeconômica foi adotado o indicador da Associação Brasileira de Empresas de Pesquisa - 2014. Para a análise da associação entre nível de conhecimento e situação socioeconômica utilizou-se o teste do qui-quadrado, a um nível de significância de 5%. Resultados: Participaram do estudo 187 mães. O bom nível de conhecimento foi o mais frequente em todas as classes socioeconômicas, no entanto, esta frequência reduz em função da condição socioeconômica (p≤0,05). Conclusão: No grupo investigado foi evidenciado que a situação socioeconômica interferiu no nível de conhecimento.
ELE, EAD Y TIC, EXPLORANDO POTENCIALIDADES EN LA UFPB VIRTUAL
Authors: Peres Martorelli Ana Berenice , Núñez Merino María José
Published: March 2018

La utilización de las Tecnologías de la Información y Comunicación (TIC) en la enseñanza y el aprendizajede lenguas extranjeras, aunque sea tema recurrente de estudios y seminarios profesionales actuales, resulta un proceso complejo que implica diversas variables, como las herramientas utilizadas (o disponibles) o el profesorado y el alumnado (con sus actitudes y competencias), además del contenido a ser presentado. En este artículo se presentan los resultados de una investigación llevada a cabo en la Universidade Federal da Paraíba-UFPB/Brasil con profesores que trabajan en la licenciatura de Letras Español, en las modalidades presencial y a distancia/en línea. Así, fueron aplicados cuestionarios para saber lo que los docentes entendían por TIC y su intervención en la enseñanza delEspañol como Lengua Extranjera (ELE), cuáles eran las herramientas 3.0 más usuales, así como las principales dificultades enfrentadas en el contexto tecnológico. Los resultados muestran que, a pesar de que las TIC forman parte de su contexto de trabajo, especialmente en los docentes de la modalidad virtual, la formación de los profesores es deficitaria en ese aspecto, sin vislumbrar totalmente el potencial (y la necesidad) de la competencia digital en los nuevos conceptos de enseñanza y aprendizaje, máxime en cursos de ELE. De esta manera, el “milagro de las innovaciones tecnológicas” todavía no se ha concretado en muchas de las clases estudiadas y se considera necesario repensar la capacitación y concienciación sobre las nuevas posibilidades que están al alcance de los profesoresformadores de futuros docentes.
Apropiación cultural de lo narco en Chile: la narcoserie Prófugos
Authors: Vásquez Mejías Ainhoa
Published: March 2018

Aunque Chile es, hasta ahora, uno de los países de Latinoamérica con menor tasa
de criminalidad derivada del narcotráfico, no ha quedado exento de la influencia de
la narcocultura, originada en Colombia y México. Chile ha realizado una apropiación
cultural (Subercaseaux, 1988) de las características de lo narco, produciendo
sus propias ficciones. En el siguiente documento se analiza la narcoserie chilena
Prófugos (2012), como un ejemplo de esta apropiación cultural, ya que –a pesar
de incluir elementos propios de la narcocultura: estilística gore, atemporalidad circular,
deslegitimidad del Estado (Santos, Vásquez y Urgelles, 2016)– incorpora
signos nacionales representativos que dan cuenta de la historia nacional reciente:
la dictadura chilena, la lucha estudiantil y el conflicto con el pueblo mapuche. Se
concluye que Chile se ha valido de un formato extranjero –la narcocultura– para
contar y analizar el contexto socio-histórico del Chile contemporáneo.
Diseño e implementación del sistema de diagnóstico de fallos usando redes de petri interpretadas y coloreadas
Authors: Murillo-Soto Luis Diego
Published: March 2018

Este trabajo muestra el diseño e implementación de un sistema de diagnóstico de fallos para un sistema hidráulico que presenta simetría en su diseño. El sistema de diagnóstico utiliza los comandos del controlador y las señales de los sensores para diagnosticar once fallos individuales o algunas combinaciones. El trabajo expone la metodología para diseñar el diagnosticador, la cual consiste de ocho etapas que buscan la extracción de información del modelo base del sistema hidráulico. Como modelo base se utiliza una red de Petri interpretada para discretizar por eventos el sistema. Por otra parte, el modelo del diagnosticador se deriva en un nuevo tipo de red de Petri coloreada que permite que esta sea independiente del controlador del sistema hidráulico lo que implica que pueda ser implementado en un computador externo y realizar diagnósticos en tiempo real; en este caso la implementación del diagnosticador fue realizada con el lenguaje LabView de NI. Una característica del diagnosticador es que su modelo permite ser escalado sin mayor esfuerzo a sistemas de gran tamaño que presentan simetría en su estructura, ya que cada nuevo subsistema que se incorpora al sistema original no altera el diseño del diagnosticador. Tampoco altera las matrices ni vectores utilizados,  pues el nuevo subsistema se incorpora como “colores” o copias del subsistema base seleccionado.
Crecimiento dimórfico y caracterización molecular de Candida guillermondi aislado de Pannicum maximun
Authors: Rosales-López Catalina , Valerín-Berrocal Karla , Jiménez-Bonilla Vilma
Published: March 2018

Candida guilliermondii es una levadura ascomicete ampliamente distribuida en el medio ambiente natural, a esta levadura se le atribuyen varias propiedades que le hacen ser de interés biotecnológico, como por ejemplo, para control biológico. En este proyecto C. guillermondii se logró aislar del zacate Panicum maximun, recolectado en plazas de futbol, orillas de calle y en potreros de la zonas de Cartago y Heredia. Se purificaron colonias pequeñas, ovoides y brotantes, de 3 a 5 µm y de color crema, a las 48 h de cultivo a 25 °C en PDA. Se cultivaron en medio líquido, para estimular el crecimiento de biomasa y poder realizar el análisis molecular, se extrajo el ADN y se realizaron las pruebas de PCR con diferentes imprimadores. Las secuencias generadas fueron comparadas mediante un alineamiento utilizando la herramienta Blast del National Center for Biotechnology Information (NCBI) y compararon con la base de datos del Gen Bank, identificando a Candida guillermondii. Se procedió a la inducción de pseudohifas, para ello se probaron diferentes condiciones de cultivo: luz, temperatura y pH, y varios medios de cultivo (fuentes de carbono, nitrógeno, medios pobres en minerales y medio con solo agaragua). Se logró la formación de pseudomicelio bien desarrollado desde las 96 h de incubación. El pH y la luz, medios como el agar agua, suplementado con sacarosa, el que no contenía fuente de nitrógeno y Vogels, fueron determinantes para la aparición de hifas en las levaduras. Concluyendo que el provocar estrés al microorganismo permite un cambio morfológico en el mismo.
Molecular Evolution in a Peptide-vesicle System
Authors: Mayer Christian , Schreiber Ulrich , Dávila Maria J. , Schmitz Oliver J. , Bronja Amela , Meyer Martin , Klein Julia , Meckelmann Sven W.
Published: March 2018

Based on a new model of a possible origin of life, we establish an efficient and stable system undergoing structural reproduction, self-optimization and molecular evolution. This system is being formed under realistic conditions by the interaction of two cyclic processes, one of which offering vesicles as the structural environment, the other supplying peptides from a variety of amino acids as versatile building blocks. We demonstrate that structures growing in a combination of both cycles have the potential to support their own existence, to undergo chemical and structural evolution and to develop unpredicted functional properties. The key mechanism is the mutual stabilization of the peptides by the vesicles and of the vesicles by the peptides together with a constant production and selection of both. The development of the proposed system over time not only would represent one of the principles of life, but could also be a model for the formation of self-evolving structures ultimately leading to the first living cell. The experiment yields clear evidence on a vesicle-induced accumulation of membrane-interacting peptide which could be identified by liquid chromatography combined with high-resolution mass spectroscopy. We found that the selected peptide has an immediate effect on the vesicles, leading to i) reduced vesicle size, ii) increased vesicle membrane permeability, and iii) improved thermal vesicle stability.
Innovative Effluent Capture and Evacuation Device Patented that Improves Behavior of Horizontal Subsurface Flow Wetlands
Authors: Cisterna-Osorio Pedro , Silva-Vasquez Gisela , Llanos-Baeza Mauricio , Lazcano-Castro Veronica , Fuentes-Ortega Ignacio
Published: March 2018

Currently, several researchers are working to improve the artificial wetlands performance and make them a competitive alternative to conventional treatment mechanisms. In the same vein, this paper analyzes the performance of subsurface flow wetlands removal by COD concentration, suggesting two different hydrodynamic solutions. Firstly, we worked on wetlands at pilot scale and in a real-scale wetland. This subsurface flow wetlands behaviour (HFSS) and its elimination results of organic matter were evaluated in function on the configuration and structure of the capture and evacuation effluent device. The traditional and innovative capture and evacuation effluent device were compared. In this experience, this innovative device designed for the collection and effluent evacuation was applied for the first time, what is in a process of patenting and constitutes an unprecedented improvement in wastewater treatment through HFSS. This innovative tool for capture and evacuation of the effluent, was designed and built to cover the entire width and height of the wetland, its incidence is in the entire cross-sectional area of the flow. The results show that the incorporation of the innovative device improves the wetland hydrodynamic condition, increasing the biodegradation yields of the carbonaceous organic matter. The HFSS behaviour was evaluated using both effluent capture and exit devices, comparing the respective removal efficiencies of organic matter and nitrogen. We analyzed the HFSS behaviour using both configurations (devices), evaluated and determined the incidence in the elimination efficiency of COD and nitrogen in both devices. Using the innovative effluent outlet device, the COD removal performance exceeds that of the conventional device by 10%. The improvement of the yield will allow the reduction of wetland surfaces for the same treatment horizon or the same pollutant load.
Effects of Commercial Activities by Type on Social Bonding and Place Attachment in Neighborhoods
Authors: Kim Byungsuk , Park Jina
Published: March 2018

Place attachment is an emotion that people experience in connection to a specific place and it is needed to maintain sustainable neighborhood community. The emotion is affected by various factors, such as experience, function, environment, and satisfaction. This study focuses on commercial structures, which are one feature that characterize the physical environments of neighborhoods. The aim of this study is to determine the effects of commercial activities in different commercial environments on social bonding and place attachment in residents. Two sites were selected for analysis due to their different commercial environments, and path analysis was used to examine the relationships among factors. The results indicate that the type of commercial environment had effects on commercial activities, including shopping frequency, and that commercial activities affected social bonding and place attachment in residents. Also, commercial activities had indirect effects on place attachment through social bonding between residents. These results suggest that the commercial environment is an important element affecting the community and place attachment of residents in neighborhoods.
Metformin Induces Apoptosis and Alters Cellular Responses to Oxidative Stress in HT29 Colon Cancer Cells
Authors: Sena Paola , Mancini Stefano , Benincasa Marta , Mariani Francesco , Palumbo Carla , Roncucci Luca
Published: March 2018

Accumulating evidence suggests that metformin, used as an antidiabetic drug, possesses anticancer properties. Metformin reduced the incidence and growth of experimental tumors in vivo. In a randomized clinical trial among nondiabetic patients, metformin treatment significantly decreased the number of aberrant crypt foci compared to the untreated group with a follow-up of 1 month. In our study, HT29 cells were treated with graded concentrations of metformin, 10 mM/25 mM/50 mM, for 24/48 hours. We performed immunofluorescence experiments by means of confocal microscopy and Western blot analysis to evaluate a panel of factors involved in apoptotic/autophagic processes and oxidative stress response. Moreover, HT29 cells treated with metformin were analyzed by flow cytometry assay to detect the cell apoptosis rate. The results demonstrate that metformin exerts growth inhibitory effects on cultured HT29 cells by increasing both apoptosis and autophagy; moreover, it affects the survival of cultured cells inhibiting the transcriptional activation of nuclear factor E2–related factor 2 (NRF-2) and nuclear factor–kappa B (NF-κB). The effects of metformin on HT29 cells were dose- and time-dependent. These results are very intriguing, since metformin is emerging as a multifaceted drug: it has a good safety profile and is associated with low cost, and it might be a promising candidate for the prevention or treatment of colorectal cancer.
Characterization and Possible Uses of Recycled Aggregates from Construcction and Demolition Waste from Mexico City
Authors: Moreno-Pérez Emiliano , Hernández-Ávila Juan , Rangel- Martínez Yamile , Cerecedo-Sáenz Eduardo , Arenas-Flores Alberto , Reyes-Valderrama Ma. Isabel , Salinas-Rodríguez Eleazar
Published: March 2018

In this study, four samples of recycled aggregates from construction and demolition waste of Mexico City were characterized, in order to find innovative uses for this type of materials. Gravel and sand from a recycling plant were analyzed, as well as recycled aggregates in the laboratory from demolished concrete collected in landfills. The characterization was carried out by means of XRD, chemical microanalysis (EDS), pH measurement and sieve analysis. The results reveal that the minerals present in the analyzed materials are triclinic feldspars, cristobalite and pyroxene which correspond to the natural aggregates, as well as variable amounts of calcite, product of the carbonation of the cement paste adhered to these aggregates and in a smaller proportion calcium hemicarboaluminate, rosenhanite and tobermorite. It was determined that the quality (amount of cement) of the original concrete that was recycled, has great influence on the granulometry and the chemical-mineralogical composition of the aggregates, since there will be different quantities and qualities of cement paste adhered to the aggregates of according to size. Finally the pH values measured in all samples fluctuate between 10.15 and 12.08, therefore it is suggested that these materials can be used in soil stabilization.
IMPLEMENTASI INOVASI PADA MODEL-MODEL PENDIDIKAN ANAK USIA DINI DI TAMAN PENGASUHAN ANAK (TPA) SERAMA KEMENTERIAN KESEHATAN RI
Authors: AZIZ ABDUL
Published: March 2018

Abstract: The purpose of this paper is to describe the implementation of early childhood education model and its innovation in Daycare SERAMA Ministry of Health RI. This research applied the descriptive qualitative design. The subject of this research was 10 students and their teacher. From this research, it showed that model full-day   program is in accordance with daycare SERAMA of the Ministry of Health and implementation of BCCT learning process can take place optimally The Expectation is that it can be used as a reference in making daycare in government institutions in providing the right and best education according to their interests, talents, and abilities. Thus, the more variety and innovation of early childhood education will be able to support the development of children optimally, so it is creating more moral and qualified Indonesian children.
Keywords: innovation, early childhood education model, and daycare
Abstrak:  Tujuan dari penulisan ini adalah untuk mendapatkan gambaran implementasi model pendidikan anak usia dini beserta inovasinya di TPA SERAMA KementerianKesehatan RI. Penelitian ini menggunakan desain deskriptif kualitatif. Subjek penelitianini adalah 10 orang siswa dan dua guru mereka. Hasil penelitian menunjukkan bahwa model program fullday sangat sesuai dengan TPA SERAMA Kementerian Kesehatan RI dan pelaksanaan proses pembelajaran BCCT pun dapat berlangsung secara optimal. Harapannya adalah agar dapat dijadikan sebagai rujukan dalam membuat TPA diinstitusi pemerintah dalam memberikan pendidikan yang tepat dan terbaik sesuai dengan minat, bakat, dan kemampuan masing-masing. Dengan demikian, semakin banyak ragam dan inovasi pendidikan anak usia dini akan mendukung perkembangan anak secara optimal, sehingga mampu mewujudkan anak Indonesia yang lebih bermoral dan berkualitas.
Kata Kunci: inovasi, model pendidikan anak usia dini, dan TPA
ANALISIS PENGEMBANGAN KECERDASAN LOGIS MATEMATIS ANAK USIA 5-6 TAHUN MENGGUNAKAN PERMAINAN TRADISIONAL
Authors: LESTARININGRUM ANIK , HANDINI MYRNAWATI CRIE
Published: March 2018

Abstract: The research aims to describe the traditional game in development of logical-mathematical intelligence to children aged 5-6 years, then what kind of traditional games that can be applied in the development of logical-mathematical intelligence to children aged 5-6 years. The research method was descriptive qualitative and quantitative to describe the complete exposure of research results through observation techniques conducted in the field in detail and description related to the development of logical-mathematical intelligence to children aged 5-6 years using traditional games. The data were obtained and conducted in kindergarten institutions in Grogol district, Kediri Regency, East Java in 2016. The results were obtained: (1) traditional games in development of logical-mathematical intelligence proved effective applied in learning children aged 5-6 Year, (2) traditional game of Congklak and Engklek developed logical-mathematical intelligence of children aged 5-6 years. The results of this research as an insight, further research development studies to develop the intelligence of other children and continue to explore various types of traditional games that can be used in early childhood learning. Keywords: logical-mathematical intelligence, children aged 5-6 years, traditional games
Abstrak:Penelitian bertujuan mendeskripsikan  permainan  tradisional dapat mengembangkkecerdasan kecerdasan logis matematis anak usia 5-6 tahun, kemudian jenis permainan tradisional apa yang dapat diterapkan dalam pengembangan kecerdasan logis matematis anak usia 5-6 tahun. Metode penelitian yang akan digunakan deskriptif kualitatif dan kuantitatif, dimana akan menguraikan secara lengkap paparan hasil penelitian melalui teknik observasi yang dilakukan di lapangan secara rinci dan jelas supaya mendapatkan gambaran terkait pengembangan kecerdasan logis matematis anak usia 5-6 tahun menggunakan permainan tradisional. Berdasarkan data yang diperoleh Penelitian ini dilakukan di lembaga TK di wilayah Kecamatan Grogol, kabupaten Kediri, Provinsi jawa Timur tahun 2016. Hasil penelitian yang diperoleh adalah: (1)permainan tradisional untuk mengembangkan kecerdasan logis matematis terbukti efektif diterapkan dalam pembelajaran anak usia 5-6 tahun, (2) permainan tradisional congklak dan engklek dapat mengembangkan kecerdasan logis matematis anak usia 5-6 tahun. Hasil penelitian ini sebagai wawasan, kajian pengembangan penelitian selanjutnya untuk mengembangkan kecerdasan anak yang lain dan terus menggali berbagai jenis permainan tradisional yang dapat digunakan dalam pembelajaran anak usia dini.
Kata Kunci: kecerdasan logis matematis, anak usia 5-6 tahun, permainan tradisional
PENINGKATAN KEMAMPUAN MUSIKALITAS MELALUI BERMAIN ALAT MUSIK DOL
Authors: YETTI ELINDRA , KHAIRIAH ICHA
Published: March 2018

Abstract: This study aims to know whether the use instrument dol can the ability of children in early childhood musical Paud Al-khair Air Napal Sub District, Bengkulu Utara Regency, Bengkulu province, 2016. The method used is action research model Kemmis & Mc Taggart. The subjects of this research were 17 children of group B in Paud Al-khair. The study was conducted in two cycles consisting of nine meetings in each the cycle. Techniques of data collection was done through observation, interviews and document study. Techniques of data analysis in this research is the analysis of qualitative data and quantitative data analysis. The results showed that the musical abilities of children in group B in PAUD Al-khair increased after they performed activities play a musical instrument dol. Scores of children's musical ability was recorded at 36.5 at the pre-cycle.Musical ability scores increased to 52.4 at the end of the first cycle and continuously increased to 59.2 at the end of the second cycle. The results of this study imply that playing a musical instrument dol can be used as one way to improve musical ability in children early age.
Keywords: Ability Music, Playing musical instruments Dol Abstrak: Penelitian ini bertujuan untuk mengetahui proses dan hasil bermain alat musik dol untuk meningkatkan kemampuan musikal anak di PAUD Al-khair Kecamatan Air Napal Kabupaten Bengkulu Utara-Bengkulu, Tahun 2016. Metode penelitian yang digunakan adalah penelitian tindakan dengan model Kemmis & Mc Taggart. Subjek penelitian adalah anak kelompok B sebanyak 17 orang. Penelitian dilakukan dalam dua siklus yang terdiri dari sembilan kali pertemuan pada setiap siklus. Tekhnik pengumpulan data dilakukan melalui observasi, wawancara dan studi dokumen. Tekhnik analisis data dalam penelitian ini adalah analisis data kualitatif dan analisis data kuantitatif. Hasil penelitian menunjukkan bahwa kemampuan musikal anak kelompok B di PAUD Al-khair mengalami peningkatan setelah mereka melakukan kegiatan bermain alat musik dol. Skor kemampuan musikal anak tercatat sebesar 36,5 pada tahap pra-siklus. Skor kemampuan musikal meningkat menjadi 52,4 pada akhir siklus I, dan terus mengalami peningkatan menjadi 59,2 pada akhir siklus II. Hasil penelitian ini memberi implikasi bahwa bermain alat musik dol dapat dijadikan sebagai salah satu carauntuk meningkatkan kemampuan musikalitas pada anak-anak usia diri.
Kata Kunci: Kemampuan Musik, Bermain alat musik Dol.
KONTRIBUSI PERMAINAN KONSTRUKTIVIS (MEDIA BALOK) DENGAN PENINGKATAN KEMAMPUAN KOGNITIF
Authors: RACHMAT FAISAL
Published: March 2018

Abstract: This classroom action research aims to determine the improvement of cognitive skills through playing blocks.The research subjects were children in group A & B Age 3-6 Years old of RA. Nurul Amiin, in a total of 23 children consisting of 9 Girls and14boys. Researchers use classroom action research methods with observation and documentation to collect data. Analysis of the data used in this research is the analysis of descriptive and qualitative.The results showed an increased ability of the students cognitive at 90% based on the evaluation of the results on the first cycle and second cycle. It can be concluded that the implementation of learning by utilizing blocks media to improve children's cognitive abilities can be implemented in the learning process. Keywords: Blocks media, Cognitive ability
Abstrak: Penelitian tindakan kelas ini bertujuan untuk mengetahui adanya peningkatan kemampuan kognitif anak melalui bermain balok. Subjek penelitian adalah anak kelompok B usia 3-6 tahun di RA. Nurul Amiin, Citayam, Depok yang berjumlah 23 anak terdiri dari 9anak perempuan dan 14 anak lakilaki. Peneliti menggunakan metode penelitian tindakan kelas dengan observasi dan dokumentasi untuk mengumpulkan data. Analisa data yang digunakan dalam penelitian ini adalah analisis deskriptif kualitatif. Hasil penelitian menujukkan adanya peningkatankemampuan kognitifanaksebesar 90% berdasarkan evaluasi hasil dari siklus I dan siklus II. Sehingga dapat disimpulkan bahwa pelaksanaan pembelajaran dengan memanfaatkan media balok untuk meningkatkan kemampuan kognitif anak dapat diimplementasikan dalam proses belajar.
Kata kunci: Media balok, Kemampuan kognitif.
PENGARUH INTENSI, MOTIVASI, DAN PEMAHAMAN GURU TERHADAP IMPEMENTASI PENDIDIKAN INKLUSIF
Authors: MULYONO RACHMAT , SUHYANTO OTONG , SIRON YUBAEDI , ROCHIMAH NUR
Published: March 2018

Abstract: The objective of the research was to find out the empirical information of the effect of intention, motivation, and teacher understanding on the implementation of inclusive education. The research used path analysis techniques. It conducted the elementary-school-teacher in East Jakarta, Indonesia. The simple random sampling technique is applied, which 50 teachers involved as the research sample. Empirical findings of the research revealed that: 1) There is no direct a positive effect of intention to the implementation of inclusive education; 2) There is no direct a positive effect of motivation to the implementation of inclusive education; 3) There is no direct a positive effect of teacher understanding to the implementation of inclusive education; 4) There is no direct positive effect of intention to the teacher understanding; 5) There is direct positive effectof motivation to the teacher understanding; 6) There is direct positive effect of intention to the motivation.
Keywords: implementation of inclusive education, intention, motivation, teacher understanding, children with special needs.
Abstrak: Tujuan penelitian ini untuk mencari informasi empiris tentang pengaruh intensi, motivasi, dan pemahaman guru terhadap implementasi pendidikan inklusif. Penelitian ini menggunakan analisis jalur. Penelitian ini mengukur perilaku guru SD di Jakarta Timur, Indonesia. Penelitian ini menggunakan teknik simple random sampling dengan melibatkan 50 guru. Temuan empiris mengungkapkan bahwa: 1) Tidak ada pengaruh langsung positif langsung intensi terhadap pendidikan inklusif; 2) Tidak ada pengaruh langsung positif motivasi terhadap pendidikan inklusif; 3) Tidak ada pengaruh langsung positif pemahaman guru terhadap pendidikan inklusif; 4) Tidak ada pengaruh positif langsung intensi terhadap pemahaman guru; 5) Ada pengaruh langsung motivasi terhadap pemahaman guru; 6) Ada pengaruh langsung intensi terhadap motivasi.
Kata Kunci: implementasi-pendidikan-inklusif, intensi, motivasi, pemahaman guru, anak berkebutuhan-khusus
MODEL PEMBELAJARAN BERORIENTASI FUNDAMENTAL DENGAN PERMAINAN AIR UNTUK ANAK 5 - 6 TAHUN
Authors: PUSPITORINI WAHYUNINGTIAS , KURNIATI RIZKI , TANGKUDUNG JAMES
Published: March 2018

Abstract: The purpose of this research are; (1) develop fundamental movement-based learning using water games for children 5-6 years and (2) obtain empirical data on the effectiveness of the results of model development fundamental movement-based learning using water games for children aged 5-6 years. Subjects in this study were children aged 5-6 years in kindergarten. Place of research conducted in the city of Palembang. This study is the development of the Research and Development of Borg and Gall. Product results of the research is a fundamental movement guidebook using water games. Research shows that: (1) the development of fundamental movement-based learning using water games for children aged 5-6 years have been declared invalid by a motor learning, physical activity experts, and practitioners of early childhood education, (2) fundamental movement-based learning using water games proved 85% can improve fundamental skills and helps to build a sense of confidence and courage.
Keywords: fundamental movement, water games, children aged 5-6 years.
Abstrak: Tujuan dari penelitian ini adalah; (1) mengembangkan pembelajaran berbasis gerakan fundamental dengan menggunakan permainan air untuk anak-anak 5-6 tahun dan (2) memperoleh data empiris tentang keefektifan hasil pengembangan model pembelajaran berbasis gerakan dasar dengan menggunakan permainan air untuk anak usia 5-6 tahun. Subjek dalam penelitian ini adalah anak usia 5-6 tahun di taman kanak-kanak. Tempat penelitian dilakukan di Kota Palembang. Penelitian ini merupakan pengembangan dari Penelitian dan Pengembangan menggunakan rancangan Borg dan Gall. Hasil produk penelitian ini adalah buku panduan pergerakan fundamental dengan menggunakan game air. Penelitian menunjukkan bahwa: (1) pengembangan pembelajaran berbasis gerakan fundamental dengan permainan air untuk anak usia 5-6 tahun telah dinyatakan tidak berlaku oleh pembelajaran motorik, ahli aktivitas fisik dan praktisi pendidikan anak usia dini, (2) pembelajaran berbasis gerakan dasar Menggunakan permainan air terbukti 85% dapat meningkatkan keterampilan dasar dan membantu membangun rasa percaya diri dan keberanian.
Kata Kunci: gerakan Fundamental, Permainan air, Anak usia 5-6 Tahun