bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison between Topical Platelet-rich Plasma and Normal Saline Dressing in Conjunction with Total Contact Casting in Treatment of Diabetic Foot Ulcer – A Randomised Control Trial
Authors: Das Subha , Kumar Anjani , Kumar Sanyal , Pandey Sanjay Kumar , Kumar Niraj , Kumar Ranjeet
Published: November 2024

Introduction:

Effective wound care is crucial in managing diabetic foot ulcers (DFU), with practices such as wound cleaning and maintaining moisture being essential. The total-contact cast (TCC) is a recognized and effective method for off-loading plantar ulcers. This study compares the effectiveness of platelet-rich plasma (PRP) and normal saline (NS) dressings, both combined with TCC, in the treatment of DFUs.

Methods:

A total of 108 patients with diabetic foot ulcers were randomly divided into three groups: PRP, NS, and TCC, with 36 patients in each group. The PRP group received autologous PRP followed by TCC application, the NS group received wet NS dressings followed by TCC application, and the TCC group had TCC alone. Patients were followed every 15 days for 90 days, with wound measurements taken and TCC reapplied at each visit. Wound healing was assessed based on the time to heal and the PUSH score.

Results:

Baseline wound sizes were similar across groups, but by day 90, the PRP group showed a greater reduction in wound size (0.61±1.20) compared to the NS (1.58±1.55) and TCC groups (1.22±1.34). The PRP group also had the most significant improvement in PUSH scores, indicating superior wound healing.

Conclusion:

PRP, NS, and TCC are all effective in DFU treatment, but PRP combined with TCC is statistically superior in enhancing wound healing and reducing the frequency of hospital visit.
The Biomechanical Interpretation of Claw Hand Deformity with Principle and Application of Anti-claw Orthosis/Splint in Hand Rehabilitation: A Descriptive Management Strategy in Daily Clinical Practice
Authors: Prakash Achintya , Kumar Raj
Published: November 2024

Orthosis/splints for the claw hand deformity have been in use for several decades for rehabilitation of the hand after isolated ulnar palsy or combined ulnar and median nerve palsy. In the current study, we have reviewed the anatomy and pathomechanics of claw hand deformity, the mechanical principles of various types of hand splints/orthosis and their clinical application in hand rehabilitation.
Hepatitis B Vaccination Status, Knowledge, and Attitudes among Healthcare Workers in Military Hospital, Khartoum State: A Cross-sectional Study
Authors: Yahia Saffaa , Babiker Somia , Mohamed Moatasem Gasmallah , Ahmed Abazar Hussin , Babiker Ameen Awad Al-Amin , Altayeb Ehab Ahmed , Hassan Hassan Gamal , Maisra Mubark , Saeed Ali Awadallah
Published: November 2024

Background:

Hepatitis B virus (HBV) is a significant public health issue that causes a substantial number of cases of hepatitis-related illness and death. It is particularly important to vaccinate healthcare workers (HCWs), as they face a higher risk of HBV infection due to their exposure to infected blood and other bodily fluids in their line of work. The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention currently recommends HBV vaccination for adult populations at risk of infection. Therefore, this study aimed to assess the vaccination status, knowledge, and attitudes of HCWs toward HBV vaccination in a military hospital.

Materials and Methods:

An institution-based descriptive cross-sectional study performed between May 2022 and September 2022 for HCWs working in Omdurman Military Hospital who were available at the time of data collection; data were collected using a self-administered and online questionnaire; the obtained results were analyzed.

Results and Conclusion:

Only 50% of HCWs in military hospitals possessed adequate knowledge, while the majority exhibited a positive attitude toward HBV infection. In terms of vaccination status, approximately two-thirds of HCWs were immunized, but only half of them completed the recommended number of vaccine doses. The educational activities of the infection control training programs should be strengthened to enhance the awareness of HCWs regarding HBV infection and vaccination. It is necessary to implement comprehensive vaccination programs against hepatitis B in various medical fields. In addition, a mandatory and cost-free policy for hepatitis B vaccination should be established for HCWs and medical students.
Effectiveness of Chlorambucil as Front-line Therapy in Sudanese Patients with Chronic Lymphocytic Leukemia Attending Khartoum Oncology Hospital
Authors: Mohammed Suad Z. , Ali Nadeen T. , Ahmed Kannan O. , Yousef Bashir Alsiddig
Published: November 2024

Background:

Chlorambucil was the standard of care therapy in chronic lymphocytic leukemia (CLL), it becomes restricted for a specific type of CLL population, due to the launching of more effective anticancer agents. However, in Sudan, chlorambucil remains the first-line therapy in CLL. Thus, the study aimed to determine the effectiveness of chlorambucil in Sudanese CLL patients who attended the Khartoum Oncology Hospital from January 2014 to October 2017.

Methods:

This was a descriptive retrospective hospital-based study in which files of patients who met the inclusion criteria were critically reviewed using a data collection sheet. The main response indicative parameters were lymphocytes count, lymph node enlargement, and organomegaly status. Effectiveness was assessed by measuring the overall response rate (ORR) as the primary endpoint and the progression-free survival (PFS) as the secondary endpoint.

Results:

A total of 64 patients were included, 62.5% of them were male. The majority of them (59.4%) were aged ≥65 years old. Clinically, 43.8% of these patients were at stage IV. Around 63.1% of the patients received high dosages of chlorambucil. The median PFS for chlorambucil was 18 months. The complete clinical and partial remission rates were 24.4% and 20%, respectively. The ORR was significantly higher with the higher dose of chlorambucil (P = 0.019). While in terms of PFS, there was an insignificant difference between high dose (15 months) and small dose (22 months) of chlorambucil.

Conclusion:

In CLL Sudanese patients, chlorambucil was shown to have low response rates. High doses of chlorambucil lead to induction of better ORR, but there was no additional benefit in PFS compared to those who received low doses of chlorambucil.
Band in Hand - A Case Report of Rubber Band Syndrome
Authors: Sundaram Subbulakshmi , Swaminathan G. Ashok , Narayanan Anish Sunder
Published: November 2024

Rubber band syndrome (RBS) is a rare condition that occurs in children who wear rubber bands around their wrists for decorative or religious purposes. Over a period of time, the rubber bands have the potential to pierce through the skin and soft tissues, causing constriction and damage to the underlying structures. We present the case of a 4-year-old boy with painless swelling of the right wrist, which was later diagnosed as RBS. This case highlights the importance of raising awareness about the potential dangers of wearing rubber bands on the wrist and the need for prompt diagnosis and management to prevent further complications.
Identification of a Social Problem: Fast-food Intake among Youth – An Interactive Narrative Review
Authors: Krubaa P.
Published: November 2024

Fast food is a type of food that is prepared and served quickly, often available for take-out or drive-thru, and typically offered by restaurants, chains, or franchises. This is an interactive narrative review that brings to the surface the real challenge of youth fast-food consumption as an emerging issue linked with serious health complications such as obesity, diabetes, and cardiovascular diseases. According to many research studies, it has been indicated that young people “over-consume” fast foods hugely, whereby in the United States, 34% of children and adolescents consume fast food daily, and similar trends are being observed across the globe. For instance, some of the contributing factors such as convenience, affordability, aggressive marketing, and high accessibility, together with parental influence, have acted as the potential reasons behind this behavior. These facts highlight the importance of establishing efficient food-related lifestyle modification measures. Among the existing solutions are nutrition education, new policies for school meals, parental involvement, rules for food marketing, and community-based applications. Once more, however, the implementation of such measures is hindered by budget constraints, resistance to market regulations, and a plethora of cultural preferences. These challenges can be mitigated by innovative approaches such as gamifying healthy eating, through augmented and virtual reality experiences, using healthy food trucks, and partnering with social media influencers. Other innovations are the redesign of healthy school cafeterias and classes using these interactivities to spark young minds to embrace the food laboratory experiences. New ideas are also shared in terms of community-shared agriculture programs, digital educational resources for parents, youth-led advocacy groups, and virtual cooking competitions. The final remark underscores the necessity of developing multidimensional, innovative approaches incorporating gamification, technology, and community that help foster a healthy eating environment for children. By empowering our young people as agents of change and arming families, schools, communities, and policymakers with the right skills and tools, we can reduce the risks for health problems related to fast-food consumption and offer brighter prospects for long-term health gains among the younger generation.
A Cross-Sectional Study of the Use of Antigen Rapid Diagnostic Tests for Community Identification of Severe Acute Respiratory Syndrome Coronavirus-2 in Kenya
Authors: Masaba Rose , Siamba Stephen , Hoffman Heather J. , Osire Edyth , Kimani Njoki , Kwasa Magoma , Songane Mario , Denoeud-Ndam Lise
Published: November 2024

Mass testing with antigen-detecting rapid diagnostic tests (Ag-RDT), including testing of asymptomatic individuals, is expected to improve the identification of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections. Mass testing was offered at large gatherings to determine the SARS-CoV-2 case detection rate and the acceptance and cost of implementing this community testing strategy. In 49 high-attendance venues in Kiambu County, Kenya, from June to September 2022, individuals 2 years and older were offered coronavirus disease 2019 (COVID-19) testing, vaccination, and participation in a survey. Polymerase chain reaction (PCR) testing and genome sequencing were conducted for those testing positive by Ag-RDT and those testing negative but with COVID-19 symptoms. Costs were collected from financial records, budgets, and invoices and estimated from a health systems perspective using a micro-costing method. A total of 4,062 individuals were offered testing. The testing acceptance was 3,174/4,062 (78.1%). The case detection rate was 34/3,174 (1.07%; 95% CI: 0.7–1.4%), and 11/34 (32%) of the positives were asymptomatic. The PCR results were available for 27 Ag-RDT‒positive participants and 14 Ag-RDT‒negative participants with SARS-CoV-2 symptoms and were positive in 24/27 (88.9%) and 4/14 (28.6%), respectively. Circulating variants were identified in 11 participants. Community mobilization was the major cost driver (26%) followed by purchase of SARS-CoV-2 Ag-RDTs (20.5%). The cost per individual tested was USD $15.89, and the cost per individual tested positive for SARS-CoV-2 was USD $1,484. The study demonstrates that SARS-CoV-2 Ag-RDTs could be used for identification of SARS-CoV-2 infections in both symptomatic and asymptomatic individuals at mass gatherings.
Optimizing the Use of Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Diagnostic Tests for the Timely Detection of and Response to COVID-19 in Schools and Markets in Uganda
Authors: Mulondo Jerry , Nayiga Susan , Nuwagaba Winnie , Nayebare Patience , Namuganga Jane Frances , Ssewanyana Isaac , Kamya Moses R. , Nankabirwa Joaniter I.
Published: November 2024

The early detection and management of infections is crucial to control epidemics. We evaluated the feasibility and utility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen rapid diagnostic tests (Ag-RDTs) for the timely detection of and response to coronavirus disease 2019 in high-risk border communities in Uganda. Between May and September 2022, monthly cross-sectional surveys were conducted in 11 schools and two markets in two border districts. Only baseline and end-line testing were also performed in matched control communities. Antigen rapid diagnostic test results and demographic and clinical data were collected, and contacts of patients were traced and tested. All patients were advised to self-isolate, and compliance was assessed on day 5. We enrolled 10,406 participants out of 10,472 screened individuals. The participants had a 1.3% test positivity rate, with schools recording higher, but non-significant, positivity rates than markets (1.4% versus 0.9%; P = 0.149). We tracked 556 contacts, and 536 (96.4%) agreed to test. The test positivity rate was significantly higher among contacts than the index participants (8.8% versus 1.3%; P <0.001). Only 55 (29.7%) of the index participants self-isolated effectively. Settings that received monthly testing had lower end-line positivity rates than controls (0.3% versus 1.4%; P = 0.001). Repeated SARS-CoV-2 Ag-RDT testing is feasible and could reduce SARS-CoV-2 infections. However, the participation in testing may have been enhanced by the compensation provided. Also, isolation was limited, which may reduce the impact of the intervention when rolled out on a large scale. Innovative strategies to increase the isolation of patients could improve the utility of early testing for transmission reduction during epidemics.
A Case of Cryptococcosis Due to a New Cryptococcus Neoformans Sequence Type in a Patient with Human Immunodeficiency Virus Infection
Authors: Dai Fangfang , Yu Yanhua , Lou Jinli , Lu Xinxin
Published: November 2024

In this article, we report a male patient infected with HIV presenting with cryptococcal meningitis, pneumonia, and bloodstream infection, along with intestinal obstruction and gastrointestinal bleeding. Cerebrospinal fluid and bloodstream analyses revealed the presence of Cryptococcus neoformans complex. The isolated strain was sequenced and was found to belong to Cryptococcus neoformans var. grubii with a new sequence type (ST). The strain led to fatal multisystemic cryptococcosis in a short time, and the patient died due to hemorrhagic shock because of gastrointestinal bleeding despite emergency rescue efforts. There are few reports about cryptococcosis in HIV-infected patients caused by new ST isolates. We report a new Cryptococcus neoformans ST (ST702) isolate causing infection in an HIV-infected patient, which merits further study and clinical attention.
Diversity and Prevalence of Helminths and Protozoa Among Pregnant Women in Tropical Ecuador: Implications for Chemotherapy
Authors: Calvopina Manuel , Contreras Jesse , Cevallos William , Lee Gwenyth , Levy Karen , Eisenberg Joseph N. S.
Published: November 2024

Deworming for pregnant women using a single dose of albendazole or mebendazole is recommended by the WHO in areas where the baseline prevalence of hookworm and/or trichuriasis is >20%. However, other helminths and protozoa infecting pregnant women are not affected by these drugs and dosages. To assess the prevalence and diversity of intestinal helminth and protozoan infections, we analyzed stool samples from pregnant women recently enrolled into a birth cohort, along a rural-urban gradient in northern coastal Ecuador from 2019 to 2022. Participants provided a stool sample in their third trimester (n = 444). Samples were concentrated by the Ritchie method and observed microscopically for the detection of cysts, eggs, and larvae. The overall prevalence of infection with one or more parasites was 69% (95% CI: 67–74%), ranging from 52% in urban participants to 76% in rural participants (percentile rank = 1.39, 95% CI: 1.07–1.87). This differential between urban and rural communities persisted when data were disaggregated into helminth and protozoan infections (prevalence = 19% and 46%, respectively, in urban participants compared with 42% and 58% among rural participants). The most prevalent helminth was Ascaris lumbricoides (27%), followed by Trichuris trichiura (13%) and hookworm (7.4%). Hymenolepis nana, Strongyloides stercoralis, and Enterobius vermicularis were also observed. Six protozoan pathogens were detected, including Entamoeba histolytica/dispar (23%), Giardia intestinalis (5%), and Balantidium coli, along with nine protozoa that are nonpathogenic or of debated pathogenicity. The high infection burden and diversity of intestinal parasites found in this study highlight a need to revise strategies for preventing and treating intestinal parasitic infections in pregnant women.
Current High Prevalence of Intestinal Parasitic Contamination in Fresh Vegetables in Northeast Thailand
Authors: Poochada Worawan , Uengchuen Kodchakorn , Junggoth Rittirong , Donprajum Tongpak , Seesophon Sakda , Sanpool Oranuch , Laoraksawong Pokkamol
Published: November 2024

Although fresh vegetables are a vital source of essential nutrients and dietary fiber, they can pose a significant health risk due to contamination by intestinal parasites (IPs). The consumption of contaminated vegetables can lead to intestinal parasitic infection, which is a major public health issue, particularly in tropical and subtropical regions, where sanitation, clean water, and agricultural practices are often inadequate. Northeast Thailand, with its warm, humid climate and predominant agricultural sector, exhibits a high prevalence of IPs in humans. This study aimed to determine the prevalence of intestinal parasitic contamination in vegetables in Khon Kaen, Thailand, because of its reported high prevalence of IPs. A total of 300 samples, including cilantro, celery, Thai basil, lettuce, cucumber, Chinese kale, white cabbage, Chinese cabbage, peppermint, and yard-long beans, were collected from 10 markets across five districts in the province. Each sample was washed with 1% normal saline, shaken for 15 minutes, and allowed to sediment. The sediment was then centrifuged and examined by parasitologists under a microscope. The overall prevalence of IPs was found to be 36.0%, with Blastocystis hominis (24.7%), Strongyloides stercoralis (13.0%), and Ascaris lumbricoides (8.7%) being the most common. Peppermint showed the highest prevalence rate at 70.0%, followed by celery and Thai basil at 53.3% each. These results suggest a necessity for key health policy interventions, including appropriate health education. Sanitary measures, such as washing vegetables before consumption and washing hands after harvesting vegetables, should be encouraged among farmers, sellers, and consumers.
Challenges and Strategies for Mainstreaming Neglected Tropical Diseases Campaign Interventions in Ethiopia
Authors: Hailu Awraris , Gebre Teshome , Seife Fikre , Enbiale Wendemagegn , Tamiru Adugna , Yohanes Tsegaye , Yohannes Amsayaw , Kitu Melese , Merdekios Behailu , Kebede Biruck , Kebede Fikreab , Deribe Kebede , Burton Matthew J. , Habtamu Esmael
Published: November 2024

Mainstreaming neglected tropical diseases (NTDs) interventions in national health systems is one of the key strategies emphasized in the WHO Roadmap for NTDs. However, there is limited evidence on implementing the proposed mainstreaming approaches effectively. We used a participatory ranking methodology in Ethiopia, using consultative workshops with purposively selected stakeholders, including NTDs program leaders from the government and partners, primary health care (PHC) workers, and community leaders and volunteers. Our aim was to identify, rank, and contextualize mainstreaming challenges and strategies, which were then synthesized using the Primary Health Care Performance Initiative framework. Thirty-three stakeholders at the national, regional, district, PHC, and community levels participated in two consultative workshops conducted in the Adama and Shashemene towns in Ethiopia. The stakeholders identified 73 mainstreaming challenges related to service delivery (32 [43.8%]), inputs (22 [30.1%]), systems (18 [24.7%]), and outputs (1 [1.4%]). The top three most frequently cited and ranked challenges were poor data recording and reporting, poor drug management and logistics, and weak supportive supervision and monitoring. Among the 185 strategies identified to address these challenges, the three most frequently cited were establishing a strong, supportive supervision and monitoring system, continuous on-the-job training to build workforce competence, and performance-based motivation. Multifaceted NTDs campaign intervention mainstreaming challenges that are deep-rooted in the health system were identified. The suggested strategies to address them should be given due consideration not only to guide future mainstreaming efforts but also to facilitate health system strengthening.
Human-Centered Design to Respond to Public Health Crises: Maintaining Canine Rabies Vaccination during the COVID-19 Pandemic in Peru
Authors: Castillo-Neyra Ricardo , Díaz Elvis W. , Ortiz-Cam Lizzie , Porras Guillermo , De La Puente-León Micaela , Condori Gian Franco , Chuquista-Alcarraz Olimpia , Recuenco Sergio E. , Tamayo Laura D. , Buttenheim Alison M. , Paz-Soldan Valerie A.
Published: November 2024

In the early coronavirus disease 2019 pandemic, limited understanding of severe acute respiratory syndrome coronavirus 2 transmission and fears of infection hindered mass dog vaccination efforts in dog rabies-affected areas. Interruption of dog rabies vaccination campaigns could lead to a rapid increase in the risk of human rabies. To address these challenges, we applied human-centered design (HCD) principles to develop a vaccination strategy that prioritizes safety while ensuring dog rabies vaccination continuity in Arequipa, Peru, a rabies-affected area. We describe the process of rapid prototyping and testing undertaken by our research team to adapt the vaccination process in response to a health crisis. A multidisciplinary team met twice a week to prototype a fixed-point vaccination campaign that ensured distancing and reduction of fomite transmission while allowing for the continuation of dog vaccination. Field notes and videos informed successive meetings. The final prototype was used in rabies hotspots. In 4 weeks, six prototypes of safe booths and supporting safety protocols were designed, and two copies of each prototype were field tested. During testing, additional innovations were identified and implemented, including virtual vaccine certificates and online data collection forms. The final prototype was implemented across 251 sites, and 17,876 dogs were vaccinated. Using HCD principles, we swiftly developed a mass vaccination strategy that provided safety and enabled the maintenance of rabies vaccination programs. This work highlights the importance of innovative and adaptive approaches to address public health challenges in times of crisis.
Exploring Geophagy as a Risk Factor for Neurocysticercosis: A Case Series from the Democratic Republic of the Congo
Authors: Mukuku Olivier , Sánchez Sofía S. , Bugeme Marcellin , Garcia Hector H.
Published: November 2024

Neurocysticercosis (NCC) is a common parasitic neuroinfectious disease caused by humans becoming intermediate hosts in the life cycle of the pig tapeworm, Taenia solium, after ingesting its eggs. This case series examines seven female patients with NCC who engaged in geophagy (soil consumption) and were evaluated at Centre Médical Baraka in Lubumbashi, Democratic Republic of the Congo, from January 2019 to December 2020. From a cohort of 176 patients with epilepsy evaluated during that period, 105 underwent brain computed tomography scans, and 36 were confirmed to have NCC. Among those with NCC, seven (19.4%) had a history of geophagy and were included in this case series. The majority of these patients had more than five brain lesions. Neuroimaging revealed colloidal lesions, third-stage lesions, and calcifications in six patients. All patients showed improvement after treatment with antiseizure medication alone or in combination with antiparasitic drugs. Geophagy, although not common, serves as a mode of contamination in which individuals ingest soil containing Taenia eggs, potentially leading to the development of NCC.
Splenic Modulation of Plasmodium vivax Relapses and Hypnozoite Activation during the Second World War?
Authors: Shanks G. Dennis
Published: November 2024

Despite their colonial experience with tropical medicine, Allied (United States, United Kingdom, Australia, and India) Armies in the Indo-Pacific region were surprised by the large number of Plasmodium vivax infections in their soldiers during the Second World War. Even after the institution of effective chemoprophylaxis with quinacrine, multiple cycles of clinical relapses often occurred when months of medication was discontinued. Nearly monthly symptomatic relapses (>10) were not unusual and resulted in important manpower losses after each campaign. Retrospective consideration suggests that small splenic size was associated with the risk of recurrent clinical episodes of vivax malaria. Potential non–mutually exclusive explanations for frequent relapses of vivax malaria in soldiers are reviewed. These include decreased retention of parasitized red blood cells by small spleens through greater filtration stringency preventing relapses from becoming clinically patent; small spleen size being a marker of lower innate and/or acquired immunity, modulating the risk of clinically patent recurrences; or small spleen size increasing the number of relapses through decreased removal of triggers of hypnozoite activation. Apparent splenic modulation of vivax malaria relapses suggests a complex interaction between the parasite and host that might be amenable to manipulation to facilitate malaria elimination.
Teologia pamięci według św. Tomasza z Akwinu. Głos w dyskusji
Authors: Gałuszka Tomasz
Published: November 2024

Kiedy dogmatyk zastanawia się, gdzie szukać inspiracji dla teologii archiwum, powinien zacząć nie od rzeczy, nawet nie od człowieka, ale od samej Trójcy Świętej i Osoby Boga Ojca, czyli od Tego, który jest początkiem, jest pamięcią, ale również posiada takie cechy, które dla nas, archiwistów, czy też zajmujących się refleksją teologiczno-filozoficzną nad archiwum, są kluczowe oraz intuicyjnie ich dotykamy. Teologia Boga Ojca staje się więc punktem wyjścia dla dyskusji nad tym, gdzie w ogóle szukać zakorzenienia dla teologicznej refleksji nad pamięcią i samym archiwum.

Theology of memory according to St Thomas Aquinas. A voice in the discussion:

When dogmatists consider where to look for inspiration regarding the theology of the archive, they should start not from things, not even from man, but from the Holy Trinity and God the Father, i.e., from the One who is the beginning, is memory, but also has such features which for us, archivists or those involved in theological and philosophical reflection on the archive, are crucial and which we touch intuitively. The theology of God the Father therefore becomes a starting point for a discussion on where to look for roots regarding theological reflection on memory and the archive itself.
Implementasi Job Hazard Analysis (JHA) pada Pekerjaan Distribusi Air Minum di PT. XYZ
Authors: Mutiarani Mutiarani , Fajar Aditya Dwi Putra , Hakim Rahman , Purba Adi Syahputra
Published: November 2024

Drinking water distribution work at PT. XYZ as a supporting part of the construction industry, involves a series of processes that have the potential to be dangerous and have high risks for workers. To ensure worker safety and health, identifying potential hazards and risks is important. The Job Hazard Analysis (JHA) method is an effective solution for carrying out this identification. This study aims to carry out the process of identifying potential hazards and risks and their control in the work of delivering drinking water supplies at PT. XYZ, using the JHA method. This approach allows systematic analysis of each step of the work, so that potential hazards can be clearly identified and the level of risk can be evaluated in depth. The results of the JHA analysis can be used as a basis for formulating effective control strategies to prevent accidents and injuries in the work environment. Based on the study results, the level of risk obtained at each stage of work before implementing controls varies but ranges between H12 or M9. After implementing risk control the residual risk value obtained is reduced to range between L2 to M6. The lowest residual risk value, namely L2, was obtained for the danger of negligence when checking vehicle oil from the previous value of M9 and the highest residual risk value of M6 was obtained for the danger of slippery floors when washing the vehicle from the previous risk value of M9.
Relationship Between Clinical and Laboratory Parameters at Admission and Pregnancy Outcomes in Cases of Preterm Premature Rupture of Membranes
Authors: Aslan Ferhat , Köstü Bülent , Özer Alev , Erkayıran Ugurkan , Arslan Güven
Published: November 2024

Abstract
Background: Preterm premature rupture of membranes (PPROM) is a significant complication in pregnancy, often associated with adverse maternal and fetal outcomes. Understanding the relationship between clinical and laboratory parameters at admission and pregnancy outcomes in PPROM cases is essential for effective management and intervention.
Methods
The study was conducted retrospectively to examine the relationship between clinical and laboratory parameters at the time of admission and the latent period in pregnant women with PPROM. Records of pregnant women diagnosed with PPROM between 2015-2017 in the obstetrics department of a university hospital were reviewed. The patients were grouped according to gestational weeks, clinical parameters at admission were recorded, and their relationships with the latent period were analyzed.
Results
When the data obtained in the study were analyzed, it was shown that cervical length (p = 0.008) and the gestational week at the time of admission had an effect on the latent period (p
A PRE-EXPERIMENTAL STUDY TO ASSESS THE KNOWLEDGE REGARDING MENTAL HEALTH PROMOTION AND EARLY IDENTIFICATION OF MENTAL ILLNESS IN ADOLESCENCE AMONG TEACHERS IN SELECTED SCHOOLS OF GUJARAT.
Authors: varghese Mr. Jibin , Kaur Dr Amandeep
Published: November 2024

Adolescence is a unique and formative time. The necessity of emotional health in teenagers, are pre- essential
for their psychological, social, physical, intellectual and instructive improvement, which are much perceived.
Multiple factors such as poverty, abuse or violence hampers children psychological status make them
vulnerable to mental health problems. Emotional wellbeing seeks to foster individual competencies, assets, and
intellectual qualities, and to fortify network advantages to prevent mental disorder and enhance prosperity and
personal satisfaction for individuals and networks. Positive psychology offers new methodologies for bolstering
mental versatility and for advancing mental health, in this way may improve endeavours of wellbeing
advancement by and large and of emotional well-being advancement explicitly. SETINGS AND DESIGN:
Quantitative evaluative research approach was discovered to be suitable for present study to check impact of
structured teaching program on knowledge regarding mental health promotion and early identification of
mental illness in adolescence among teachers in selected schools of Gujarat. One group pre-test and post-test
Pre-Experimental Research Design was used. The population for the present study was 500 School teachers at
selected district of Gujarat. Probability sampling technique was used for this study. RESULTS Prior to the
administration of teaching Programme, it was that out of 500 school teachers, major part of the sample 361
(72.2%) were under moderate category, but after the administration it was noted that major part of the
teachers were found in the excellent category 223 (44.6%).
EXAM ANXIETY AND DEEP BREATHING EXERCISES
Authors: mangala v ms mangala , rao Dr. Dipika
Published: November 2024

Anxiety plays a negative role in the academic performance of the students and also endanger to other physical
illnesses. Students with high anxiety are prone to perform academically poor and have impaired verbal working
memory skills due to distraction during their anxious state. Due to high competition, parent’s pressure and high
expectations, fear of failure, dilemma about the future are the notable factors incline to aggravate anxiety among
students. Anxiety could be aggravated and experienced by students in conditions such as class atmosphere;
interaction with peer group members, examination fears, teacher student interaction and relationships, academic
work load, negative attitude towards a particular course or curriculum can be said as state anxiety. There are
many ways to breathe deeply, so play around to find one that feels natural to you. Being mindful can enhance
your deep breathing practice.is about recognizing your emotions and what’s going on in your body without
judging any of it as bad or good.
Анализ факторов в системе экономической безопасности предприятия
Authors: Ф.И. Пилова , А.А. Хамоков , А.А. Аргашокова
Published: November 2024

В статье рассматриваются факторы, непосредственно воздействующие на экономическую безопасность предприятия. Проводится анализ внешней и внутренней среды экономической безопасности предприятия. Определены угрозы экономической безопасности предпринимательской деятельности и пути их преодоления.

The article examines the factors that directly affect the economic security of the enterprise. The analysis of the external and internal environment of the economic security of the enterprise is carried out. Threats to the economic security of entrepreneurial activity and ways to overcome them are identified.
Структура налоговой системы Российской Федерации: особенности и составные элементы
Authors: З.М. Лайпанова , А.Б. Хубиева
Published: November 2024

В статье рассматриваются структура налоговой системы Российской Федерации, ее особенности и составные элементы. Проанализированы основные характеристики налоговой системы, включая принципы налогообложения, состав налоговых органов и виды налоговых обязательств. Особенное внимание уделяется многоуровневой системе налогообложения, которая включает федеральные, региональные и муниципальные налоги, а также их специфические особенности и ставки. Рассматриваются актуальные вопросы налогового администрирования и проблемы, с которыми сталкиваются налогоплательщики и налоговые органы. Даются рекомендации по оптимизации налоговой системы.

The article examines the structure of the tax system of the Russian Federation, its features and constituent elements. The main characteristics of the tax system are analyzed, including the principles of taxation, the composition of tax authorities and types of tax liabilities. Special attention is paid to the multilevel taxation system, which includes federal, regional and municipal taxes, as well as their specific features and rates. The current issues of tax administration and the problems faced by taxpayers and tax authorities are considered. Recommendations on optimizing the tax system are given.
Интернет-маркетинг в коммуникациях эффективного продвижения
Authors: С.М. Тхамокова , А.С. Варитлова
Published: November 2024

Интернет-маркетинг является неотъемлемой частью современного бизнеса, который стремительно развивается в цифровую эпоху. Этот новый подход к продвижению и коммуникациям предоставляет организациям возможность эффективно взаимодействовать со своей целевой аудиторией и установить прочные связи с потенциальными клиентами.

Internet marketing is an integral part of modern business, which is rapidly developing in the digital age. This new approach to promotion and communication provides organizations with the opportunity to effectively interact with their target audience and establish strong connections with potential customers.
ABCD/VEN-анализ для оценки приоритетов импортозамещения в сфере медицинской промышленности
Authors: Ю.А. Зуенкова
Published: November 2024

В статье представлен авторский подход к использованию традиционного ABC/VEN-анализа, адаптированного к отраслевой специфике и примененного к определению приоритетов в сфере медицинской промышленности. На примере медицинского оборудования для клинической лабораторной диагностики (анализаторов) показаны область применения анализа, а также альтернативные особенности оценки потенциала рынка для стационарного оборудования. Риски санкционного давления в сегменте лабораторного оборудования являются одними из самых высоких в связи с высокой долей зависимости от иностранного производства. На основании информации о зарегистрированных медицинских изделиях и с целью определения приоритетов импортозамещения были рассчитаны индексы – оценочный индекс импортозамещения (ОИИ) и индекс выживания (ИВ). Сформированная ABCD/VEN-матрица позволила определить приоритеты импортозамещения для российских инвесторов.

The article presents the author’s approach to the use of traditional ABC/VEN analysis, adapted to industry specifics and applied to determining priorities in the medical industry. Using the example of medical equipment for clinical laboratory diagnostics (analyzers), the scope of the analysis is shown, as well as alternative features of assessing the market potential for stationary equipment. The risks of sanctions pressure in the laboratory equipment segment are among the highest due to the high proportion of dependence on foreign production. Based on information about registered medical devices and in order to determine import substitution priorities, indices were calculated – the estimated import substitution index (OII) and the survival index (IV). The ABCD/VEN matrix formed made it possible to determine import substitution priorities for Russian investors.
Зарубежный опыт социально-экономического развития сельских территорий
Authors: Е.Н. Чеботарева
Published: November 2024

Статья посвящена изучению зарубежного опыта социально-экономического развития сельских территорий, систематизация которого позволила выявить современные общемировые тенденции. Опыт социально-экономического развития сельских территорий стран ЕС, США, Австралии, Новой Зеландии, Беларуси, Казахстана, Китая показал частичную однотипность в разрезе устойчивого сельского хозяйства и охраны окружающей среды, диверсификации сельской экономики, поддержки малых и средних фермеров, цифровизации и инноваций в сельском хозяйстве, в инфраструктурном развитии и улучшении доступа к базовым услугам. Особого внимания заслуживает их опыт по борьбе с бедностью и улучшению качества жизни, адаптации к изменениям климата, вовлечению местных сообществ и коренных народов. Результаты исследования позволяют учесть наиболее эффективные меры зарубежного опыта по социально-экономическому развитию сельских территорий, адаптированных под современные реалии новых субъектов Российской Федерации.

The article is devoted to the study of foreign experience in the socio-economic development of rural areas, the systematization of which made it possible to identify modern global trends. The experience of socio-economic development of rural areas in the EU, USA, Australia, New Zealand, Belarus, Kazakhstan, and China has shown partial uniformity in the context of sustainable agriculture and environmental protection, diversification of the rural economy, support for small and medium-sized farmers, digitalization and innovation in agriculture, infrastructural development and improved access to basic services. However, their experience in combating poverty and improving the quality of life, adapting to climate change, and involving local communities and indigenous peoples deserves special attention. The results of the study allow us to take into account the most effective measures of foreign experience in the socio-economic development of rural areas adapted to the modern realities of the new subjects of the Russian Federation.
Конкурентная среда и маркетинговые стратегии на рынке товаров легкой промышленности России
Authors: Т.А. Камалова
Published: November 2024

Изменение рыночной ситуации требует трансформации в маркетинговых подходах. Компании должны анализировать покупательское поведение и внедрять более гибкие новые бизнес-модели для удовлетворения меняющихся потребностей клиентов. Российские предприятия сталкиваются с жесткой конкуренцией на рынке с поставщиками из других государств. Из-за санкций с российского рынка ушли западные бренды, что мотивирует внимание потребителей на российские товарные марки. В условиях конкурентной экономики компании вынуждены искать способы сделать маркетинговую деятельность более эффективной. Предложены конкурентные маркетинговые стратегии развития предприятий легкой промышленности России, в том числе Республики Дагестан, позволяющие им успешно работать на конкурентном рынке.

The changing market situation requires changes in marketing approaches. Companies must analyze consumer behavior and implement more flexible new business models to meet changing customer needs. Russian enterprises face tough competition in the market with suppliers from other countries. Due to sanctions, Western brands have left the Russian market, which motivates consumers to pay attention to Russian brands. In a competitive economy, companies are forced to look for ways to make marketing activities more effective. Competitive marketing strategies for the development of light industry enterprises in Russia, including the Republic of Dagestan, are proposed, allowing them to successfully operate in a competitive market.
Применение эконометрических моделей для оценки финансовых результатов деятельности организации
Authors: Р.Е. Шокумова
Published: November 2024

В статье рассматриваются показатели оценки финансовых результатов деятельности организации и возможность применения корреляционно-регрессионного анализа для оценки влияния факторов на финансовые результаты, что дает дополнительные возможности для анализа.

The article considers indicators for assessing the financial performance of an organization and the possibility of using correlation and regression analysis to assess the impact of factors on financial results, which provides additional opportunities for analysis.
Análise da erosividade das chuvas no município de Major Isidoro, Brasil
Authors: Barreto Alice Vitória Rodrigues de , Santos Cicero Gomes , Silva Ismayla Samara dos Santos , Silva Naiane Ferreira , Oliveira José Ferreira
Published: November 2024

Existe uma ligação entre a chuva e a Erosividade, a chuva é a variável erosiva que conduz energia no sistema, por meio do impacto das gotas de chuva, que são dizimadas pela cobertura do solo. Essa energia oriunda das gotas de chuva, é determinada de Erosividade, dessa forma, o estudo objetivou estabelecer o fator erosividade (R) mediante dados pluviométricos do município de Major Isidoro – AL, situado na região semiárida de Alagoas, no período de observação de uma série histórica de dados de 1914 a 1985, A partir dos arquivos da Sudene, foram analisados dados pluviométricos. Os dados foram organizados para calcular a quantidade de chuva, o coeficiente de chuva e sua relação com a erosão, utilizando seis equações distintas. Ao longo dos 71 anos de análise, a média anual de precipitação foi de 617,59 mm. Notou-se que, nesse período, 38 anos registraram valores acima da média e 33 anos apresentaram valores abaixo. Os meses mais chuvosos foram de abril a julho, com valores acima da média. Todos os modelos estudados podem ser empregados para determinar a erosividade média mensal e anual das chuvas em Major Isidoro - AL. Os seis modelos matemáticos utilizados nesta investigação confirmaram um ajuste ao modelo linear, indicando baixa variação nos dados coletados.A erosividade média anual calculada utilizando os seis modelos matemáticos apresentaram valores que variaram de 216,08 a 5.711,46 MJ mm ha-1h-1ano-1, onde essa alta variação foi devido aos modelos matemáticos.
Big Five Personality Traits and Implementation of Green Practices of the Homegrown Restaurants in Camarines Norte: A Canonical Correlation Analysis
Authors: Abasolo Gail A. Dans- , Howard Maria Nina
Published: November 2024

The environment plays a critical role in supporting life on Earth but the rising waste management, energy, and water conservation issues pose a large threat to our environment. Since food establishments are among the largest producers of waste and users of energy and water, the study investigated whether the personality traits of the restaurant owners in Camarines Norte is a variable that affects the implementation of green practices in the operation of their restaurants using Canonical Correlation Analysis. The data were collected from thirty-four (34) restaurant owners from the province through survey questionnaires and interviews. Data from the questionnaires were tabulated and analyzed using descriptive statistics (Frequency Count, Percentage, Ranking, and Mean) and inferential statistics (Canonical Correlation Analysis).

The study revealed that conscientiousness and agreeableness were the restaurant owners’ most prominent personality traits. Restaurant owners, in general, often implement waste management, energy efficiency, and water conservation practices. The Canonical Correlation Analysis produced three canonical roots with the first two as the ones with the significant results. Results of the first canonical root imply that restaurant owners who are highly extroverted, very open-minded, conscientious, emotionally stable, and moderately agreeable highly implement water conservation practices. In the second canonical root, it inferred that restaurant owners who are highly agreeable and conscientious with moderately open minds highly implement waste management practices and only moderately implement energy and water conservation practices.
Impact of IFRS Adoption on Value Relevance of Accounting Earnings of Quoted Manufacturing Firms in Nigeria
Authors: Nornubari Nwinkonzor , Odoemelam Ndubuisi
Published: November 2024

This study investigates the impact of International Financial Reporting Standards (IFRS) adoption on the value relevance of accounting earnings for quoted manufacturing firms in Nigeria. With the increasing adoption of IFRS globally, it is crucial to understand its effect on the relevance of financial information to investors, particularly in emerging markets. A sample of nine companies listed on the Nigerian Exchange Limited (NGX) from 2006 to 2022 was analyzed to evaluate how earnings per share (EPS) and book value per share (BVPS) responded to IFRS adoption. Ordinary Least Squares (OLS) regression models were deployed in data analyses. The results show that EPS has a significant (p-value 0.05) positive relationship with share price, highlighting the importance of earnings as a critical determinant of stock prices. However, BVPS has a non-significant (p-value 0.05) and negative relationship with share price, indicating that investors in Nigerian manufacturing firms may prioritize earnings over net asset values. Interestingly, adopting IFRS does not directly impact share prices, but switching off pre-IFRS adoption (IFRS*EPS) revealed a negative and significant relationship between EPS and SP, suggesting that IFRS adoption complicates investors’ interpretation of earnings. The IFRS*BVPS indicated an insignificant relationship with the share price. Similarly, the moderating effect of firm size (FS) on the relationship between IFRS adoption and the value reverence of accounting earnings was found to be insignificant (P-value > 0.05). The study concludes that while IFRS adoption enhances transparency, it may reduce the value relevance of earnings in the short term. The findings have implications for investors, firms, and regulators, and contribute to the limited empirical evidence on IFRS adoption in emerging markets. Recommendations include improved investor communication and further research into the long-term effects of IFRS on financial performance in Nigeria.