bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ISSUE OF IMPLEMENTATION OF INTERNATIONAL STANDARDS FOR THE PROTECTION OF CHILDREN'S RIGHTS IN THE US
Authors: Ryhina Olena
Published: August 2022

The article researches the issue of implementation of international standards for the protection of children's rights under the laws of the United States. The author analyzes the provisions of the certain international treaties on the protection of children's rights, that were not ratified by the United States and did not become the part of its national law. It is established that the articles of such international acts provide the uniform minimum requirements for the protection of children's rights and ensuring "the best interests of the child", that consist of the requirements concerning normal physiological, psychological, cultural and educational development of the child. The reasons for the refusal to ratify certain international treaties on the protection of children's rights by the United States are substantiated. Among these grounds are, firstly, the peculiarities of American legal doctrine, explaining the meticulous attitude to the ratification of such international legal acts, that do not fully comply with the legal norms of national law. It is proven, that however the national mechanism for the protection of children's rights developed in the United States autonomously, but such development does accord with the requirements of international documents, despite the fact that they had not been ratified. Certain decisions of the Supreme Court of the United States evidence the facts of development of national laws on the protection of children's rights. They include the decisions of the Supreme Court of the United States adopted in 1988, 2005, 2010, 2012 and some other decisions. The first of them are the decisions on the unconstitutionality of the capital punishment and life imprisonment without the possibility of release for juveniles and persons, guilty in committing serious crimes. Consequently, the peculiarity of the US legal doctrine is its independent evolution without the ratification and implementation of international treaties, however, in reality, the United States cannot ignore global trends in the protection of children's rights
THE LEGAL SUPPORT FOR THE FINANCIAL CAPACITY OF TERRITORIAL COMMUNITIES’ ASSOCIATIONS IN FRANCE
Authors: Kaminska Mariia
Published: August 2022

Тhe article deals with the peculiarities of the French legal framework for ensuring the financial capacity of territorial communities. It is found out that in order to increase the vitality of communes and the efficiency of their activities, French law offers two options: the merger of several communes into one and the association on the basis of cooperation between them. It is observed that preference is given to the associations of intercommunal cooperation, and among such associations, those with their own taxation regime predominate. It is stated that the financial capacity of the communes is achieved primarily through their own resources and revenues to the joint budget, a significant share of which are taxes and fees, as well as financial support from the state. According to the results of the study, it is concluded that the financial capacity of territorial communities is an indicator of appropriate allocation and use of available resources in accordance with local needs as well as an effective factor in social and economic development of individual territories and the state as a whole.
THE LEGALITY OF CONTROLLING VACCINATION IN UKRAINE
Authors: Lemyk Roksolana
Published: August 2022

Generally, there is no one approach to establishing a policy for recommended or mandatory vaccination. The World Health Organization even while supporting the idea of vaccination, does not insist on an obligatory introduction to a mandatory vaccine. The introduction of immunoprophylactic measures in Ukraine becomes a debatable issue when the question arises whether the vaccination is voluntary or mandatory. Is it possible to view vaccination as an individual’s duty? Actually, it is both a matter of public protection of an individual’s health and the sanctity of an individual’s freedom. An analysis of the law currently in place gives a reason to believe that the state, declaring a systematic mandatory immunization of the population, considers it a nationwide matter. Hence accepting that the most effective way of dealing with infectious diseases and securing the health of the population and the well-being of the state, is through immunization, this should lie in the major interest of the department of public health. However, the legal system cannot foresee the problems that the implementation of immunization of the population will occur because of a lack of compliance resulting in conflict with the understanding that in Ukraine vaccination falls on the right of the patient. With every law, there is a responsibility to secure the specific subject with the realization of this law. Therefore, if in the Constitution of Ukraine, article 49, guarantees the right of protection of health, medical aid and assurance, the responsibility for prophylactic immunization lies within the state, which creates the conditions for the availability of medical aid for all citizens, as well as a certainty of an epidemic well-being. Implementing immunization concerns not only the individual person that has the right for protection, but it also relates to the general interests of society, particularly to the development of herd immunity which could be sanctioned by the state. For example, the law prohibits children who have not received timely vaccination to visit childhood institutions. Furthermore, refusal to be vaccinated by workers or members of a profession or an organization, whose activities can cause others to be infected or further spread the infection, can lead to relinquishing those activities. Presently, several European countries have adopted a stricter policy due to a decrease in voluntary vaccination and as a result a decline in general herd immunity. As a rule, courts uphold state enforcement of policies related to herd immunity. The courts take into account the correlation of the proportion of the high risk illness in the context of general health.
DISCRETIONARY POWERS IN THE DISPUTES ON THE COLLECTION OF INDEXATION OF MILITARY SERVANTS’ MONETARY SECURITY
Authors: Hirnyk Oksana
Published: August 2022

The article is devoted to the analysis of the issue of resolving in court disputes on the obligation of military units to accrue and pay the indexation of monetary security with an indication of the base month, which is taken into account for the relevant accruals. It is found that the servicemen were deprived of the right to effective judicial protection in connection with the attribution of the calculation of the indexation of monetary support to the competence of the military unit as the body in which the plaintiff served and paid him/her monetary support. The provisions of the national legislation on the indexation of monetary incomes of the population and the procedure for its accrual, which provides for mandatory rules for the selection of the base month for the accrual of indexation of monetary security, are studied. Scientific approaches to understanding the concept of «discretionary powers» as powers granted to public authorities and local governments in the process of performing managerial functions, which provide for the possibility of choosing the appropriate subjects of several possible behaviors. The decision of the courts to refuse to satisfy the claim for recovery of the indexation of monetary security with an indication of the base month, on the grounds of assigning such a prerogative to the discretionary powers of the military unit, is critically analyzed. Based on the findings of a scientific doctrine, as well as the legal positions of the European Court of Human Rights, the Supreme Court in the interpretation of the meaning of «discretionary powers» concluded that the military unit is not obliged to calculate and pay indexation of monetary security. The main arguments in favor of this position are the following: the existence of a norm of law that contains an indication of the base month, which must be taken into account when calculating the indexation of cash collateral; acquisition by the military unit of the legal status of an «employer», and not a «state body», which performs managerial functions in the relations that arise in connection with the collection of indexation of monetary security. In general, the judiciary should develop a unified approach to resolving disputes on the recovery of monetary security indexation, which provides for the obligation of the defendant to accrue and pay the indexation of monetary security taking into account the specific base month specified by law. This approach, according to the author, will ensure on the one hand the efficiency and timeliness of restoring the right of servicemen to decent pay, and on the other – will reduce the burden on the judiciary, as a person will not need to go to court again.
INTERNATIONAL STANDARDS OF THE PROCEDURE FOR APPLICATION OF DISCIPLINARY INFLUENCE MEASURES TO JUVENILE PRISONERS
Authors: Burdina Tetiana
Published: August 2022

The article examines the international legal standards of the procedure, particularly the rules and conditions, for the application of disciplinary influence measures to the juveniles sentenced to imprisonment. The author analyzes the relevant provisions of a number of such standards, namely: United Nations Standard Minimum Rules for the Treatment of Prisoners (the Nelson Mandela Rules) of 17.12.2015; European Prison Rules of 11.01.2006; Guidelines for Action on Children in the Criminal Justice System (The Vienna Guidelines) of 21.07.1997; Body of Principles for the Protection of All Persons under Any Form of Detention or Imprisonment of 09.12.1988; United Nations Standard Minimum Rules for the Administration of Juvenile Justice (The Beijing Rules) of 29.11.1985; United Nations Rules for the Protection of Juveniles Deprived of their Liberty (The Havana Rules) of 14.12.1990; The European Rules for juvenile offenders subject to sanctions or measures of 05.11.2008; Guidelines for child-friendly justice of 17.11.2010; Human rights in the administration of justice, including juvenile justice: Resolution 36/16 of 29.09.2017; Human Rights in the administration of justice: Resolution 75/185 of 16.12.2020; General comment No. 24 (2019) on children`s rights in the child justice system of 18.09.2019; Model Law on Juvenile Justice and Related Commentary: issued under the auspices of United Nations in 2013. The author finds out that the international standards for execution of punishment in the form of imprisonment of the juveniles pay special attention primarily to re-education, correction, social rehabilitation, readaptation as well as social reintegration of juvenile prisoners. The study reveals that the considered international legal acts focus, consequently, primarily on the educational impact of disciplinary measures, provide for an individual approach to juvenile prisoners, require the preservation of dignity and the welfare of juvenile prisoners, as well as enshrine the principle of proportionality of the applied measures in relation to the characteristics of the personality of a juvenile sentenced to imprisonment, and concerning to the circumstances and gravity of the offense committed by him/her. However, the author finds that the international standards, while defining a number of requirements for the application of sanctions, instead do not pay due attention to the incentives, which are mentioned only in the Nelson Mandela Rules and the European Rules for juvenile offenders
THE INTERNET IN THE SEARCH ACTIVITIES OF THE INVESTIGATOR
Authors: Kohutych Ivan , Maksymyshyn Nataliia
Published: August 2022

The article considers the possibility of using the Internet in the investigation of criminal offenses, identifies certain aspects of its use in evidence, as well as analyzes the essence of the investigator's search activities in the information field mentioned. In particular, it is noted that in modern conditions, both scholars and practitioners are increasingly paying attention to the possibility of using the possibilities of the Internet in the criminal proceedings. Nowadays, the Internet, which has become essentially a global telecommunications network, creates significant potential opportunities for law enforcement agencies to detect and investigate a large number of types of criminal offenses. However, due to the uncertainty of the legal status of the Internet, it is rapidly being criminalized. Using the achievements of scientific and technological progress, intensifying activities and increasing the level of their organization, offenders expand the information space around them, naturally forming a set of connections available for analysis by using modern scientific and technical methods and tools. In turn, domestic law enforcement agencies can and should also adequately take into account such processes and use them in terms of developing ways to use appropriate Internet sources of information on subjects of all levels of crime, especially organized, as well as with a foreign element. In general, the main objectives of using the Internet in the investigation of criminal offenses is to find the necessary forensic information from its network, its analysis, accumulation and further processing and application in the detection and investigation of illegal acts, including their proof. It is justified to single out the following areas of use of information from the Internet during the pre-trial investigation: first, as a source of operational information; second, as an information channel both for operative communication with the public, and as a means of influencing it in the interests of detection, investigation and prevention of criminal offenses; third, as a means of influencing those who have committed such offenses in order to encourage them to expose themselves either in the form of appearing before a law enforcement agency or in the form of committing erroneous actions that will facilitate their detention. One way or another, the use of the World Wide Web can contribute to changes in the pre-trial investigation, significantly increasing its effectiveness. To ensure the reliability of the information received from this network, it is necessary to improve the procedural forms of its formation, verification and evaluation, taking into account the possibility of its accidental or deliberate distortion.
DOMAIN NAMES, CORPORATE STYLE AND OTHER COMMERCIAL DESIGNATIONS: FEATURES OF LEGAL PROTECTION
Authors: Tarasenko Leonid
Published: August 2022

The article considers the features of legal protection of domain names, trade dress and other commercial designations. The legal regime of the specified objects of legal protection is analyzed. It is proved that the current national legislation does not clearly define the legal regime of the domain name, corporate style (trade dress) and other commercial designations. The issue of whether a domain name, corporate style and other commercial designations can be considered as separate objects of intellectual property rights is resolved. It is substantiated that domain names, corporate style (trade dress), and other commercial designations are the newest objects of legal protection. It is proven that a domain name is not an independent object of intellectual property, but it can only be a form of use of a trademark or other means of individualization, or can be an independent commercial or non-commercial designation. It is substantiated that the rights to a domain name depend on what objects of civil rights are reflected in the verbal expression of domain names (trademark, trade name, geographical indication, copyright object, name of an individual, etc.). It is proved that the scope and content of the relevant rights to the domain, including the protection of this right, is determined by the species belonging to the object reflected in the domain name, and mainly it is an object of intellectual property. It is established that the ways to protect the rights to the domain can be transferring of the domain name to the plaintiff or termination of the domain name. It is proved that other commercial designations are a separate object of law, which is provided for by Art. 4 of the Law of Ukraine «On protection against unfair competition». It is substantiated that «other commercial designation» is a designation (brand) used by an economic entity without the registration of rights to it, for example, as a trademark. It is proved that «other designation» is inappropriate to be considered as a separate object of intellectual property, instead such designation can be protected as a copyright object (for example, a logo) or as an independent object in a competitive relationship. It is established that the corporate style (trade dress) is inappropriate to be identified exclusively with the brand. It is proved that corporate style (trade dress) strengthens the brand, «dresses» it, creating an individual style. It is justified that it is inexpedient to single out corporate identity as a separate intellectual property object, as corporate identity is a collective, complex object, the rights to which should be protected using other intellectual property objects that are «present» in this trade dress, or are dominant in it.
ESTIMATED FINANCING OF PUBLIC AUTHORITIES AS THE MAIN TYPE OF FINANCIAL SUPPORT OF ACTIVITIES BY THE BODIES OF THE PROSECUTOR'S OFFICE OF UKRAINE
Authors: Kuleba Yuliia , Shandra Roman
Published: August 2022

The article is devoted to the analysis of the financial support issue of the activity of the Prosecutor's Office of Ukraine bodies as the implementation of the estimated financing of public authorities. The importance of the research topic is due to the need to reduce the impact of a combination of factors on the activities of the prosecutor's office, such as the national economy, social problems, the danger of politicization of this law enforcement agency. The article analyses the concepts and features of estimated financing, the concept and objectives of financial support and why it is used to finance the prosecutor's office, national financial legislation, the importance of prosecutorial remuneration for efficiency as well as fairness of criminal justice. By referring to the international standards, conclusions were drawn from the analysis of budget programs implemented by the Prosecutor General's Office of Ukraine in their areas, as well as the responsible actors and budget reporting on the activities of the prosecutor's office. The advantages and disadvantages of the budget regime of financing the prosecutor's office are studied. It is noted that despite the sufficient advantages, estimated financing also has significant disadvantages, manifested in the fact that this form does not provide sufficient incentives for rational and efficient functioning of the budget institution and does not provide a close relationship between financial resources and its results activities. Based on allocated budget allocations, budget institutions ensure the performance of their functions, which is not always realized with the ability to provide quality and affordable public services. The authors also analyse and propose new areas of research. In particular, the issue of evaluating the effectiveness of the use of budget funds by the prosecutor's office, which will be the subject of a separate scientific study, is insufficiently investigated. The research concluded that the need to improve budget funding is a basic form of financial support of the prosecutor's office, as it aims to ensure the statutory activities of budgetary institutions and provide them with socially necessary services to comply with basic principles of estimated financing. Estimated financing should be effective and ensure maximum return on the use of financial resources of the budgetary institution.
LEGAL STATUS OF THE STATE OF UKRAINE IN CIVIL LEGAL RELATIONS
Authors: Hnativ Oksana
Published: August 2022

The need for conceptual updating of civil legislation of Ukraine is one of the necessary conditions for attracting investment, ensuring proper and effective legal regulation of micro- and macroeconomic processes, which, in turn, removes obstacles to the development of new economic relations. Undoubtedly, in order to ensure the rule-making process, it is necessary to take into account the experience of foreign states, in particular the provisions of a private law nature developed within the framework of international organizations, as well as the experience of EU member states. However, when using the positive rule-making experience of foreign states and international organizations, the peculiarities of economic and political development of our state must be taken into account. One of the proposals by the developers of the Concept of updating the Civil Code of Ukraine is to consolidate the legal status of a legal entity under public law. This legislative approach aims to bring Ukraine's civil law closer to the EU and to address law enforcement issues. The state realizes its legal personality, including in the sphere of private relations, through the bodies created by it. Therefore, it seems reasonable to believe that in such conditions it is sufficient to grant the legal status of a legal entity under public law to public authorities. Each of the subjects has its own peculiarities of participation in civil relations due to the nature of origin, but this does not violate the principle of equality and does not create obstacles to entry and participation in them. The state, regardless of the peculiarities of entry and participation in civil relations, is their participant (subject) on a par with individuals and legal entities, whose participation also has its own characteristics. Moreover, enshrining in the Central Committee of Ukraine the provision that the state of Ukraine is a legal entity under public law may create additional grounds for manipulation at the political level in the context of the Russian Federation's attack on Ukraine. It is obvious that the aggressor country will use any grounds to deny the statehood of Ukraine, despite the fact that some states have a practice of consolidating the status of a legal entity under public law. The state of Ukraine is an independent participant in civil relations, which has no advantages in joining and participating in them. Peculiarities of state participation in civil relations are determined by acts of civil law in the same way as other participants in civil relations. The presence of sovereignty, as well as other features of the state, does not create advantages or obstacles to such participation. This gives grounds to conclude about the complex structure and integrity of the legal personality of the state.
CORRUPTION RISKS AS A CHALLENGE FOR THE CLIMATE CHANGE INTERNATIONAL LEGAL REGIME
Authors: Nepyivoda Ivanna , Nepyivoda Vasyl
Published: August 2022

The United Nations Climate Change Conference (Glasgow, 2021), the largest conference of the parties to date, shaped the respective international legal regime according to state-of-the-art vision. Its outcome documents reflect the principal need for immediate actions during this critical decade to keep as reachable an aim to limit global temperature rise to 1.5°C above pre-industrial levels. The reasons for the current limited success in realization of the global climate goals are rooted not in issues of macrolevel, such as North–South divide, exclusively. Though never mentioned in the principal documents of the climate change regime, the corrupt practices significantly reduce the ability to address this global challenge. The article provides an overview of the key areas of actions that all parties of the regime are expected to take in order to accelerate their efforts pursuant to the Glasgow Climate Pact. Within this framework, mitigation, adaptation, finance and collaboration are examined taking into consideration corruption risks associated with them. The article argues that implementation of the commitment to mobilize not less than USD100 billion annually for adaptation measures, as well as growing mitigation finance, a priori possess a high corruption potential. Corruption challenges impeding sectors of the global climate action such as international carbon markets, phasing-down coal power, sustainable forestry and construction projects for adaptation, are considered. The article points to 'conventional' and new, associated with uncertainty and lack of the relevant experience forms of corruption. It is noted that Glasgow efforts to fully operationalize the Paris Agreement provisions by coming to an understanding on a new mechanism and standards for international carbon markets, common reporting requirements on emissions and support, as well as common timeframes for emissions reductions targets will inhibit corruption, but will not be able to totally eradicate it. Both, climate change and corruption, have become priority issues of international concern. The article claims that responding to existing challenges the climate change international legal regime will interact with the international legal framework against corruption. Though particular forms and directions for such interaction are not clear to the moment, knowledge, norms and techniques shaped within the anti-corruption framework will be potentially useful for global climate change actions.
THE ROLE OF ENVIRONMENTAL CONTROL BODIES IN THE FIXATION OF WAR CRIMES AGAINST THE ENVIRONMENT ON THE TERRITORY OF UKRAINE
Authors: Rosokhata Daria
Published: August 2022

The article is devoted to the study of the role of environmental control bodies in recording war crimes against the environment in Ukraine and calculating damage, which will help Ukraine properly submit a case to the International Court of Justice to obtain reparations from the Russian Federation to restore the environment. The article analyzes the powers of the State Environmental Inspectorate of Ukraine in martial law as well as features of the Operational Headquarters at the State Environmental Inspectorate of Ukraine, created to ensure the formation of a list of all violations in the field of environmental protection and to help bring the Russian Federation to justice for environmental damage in Ukraine. The current issues in the recording of war crimes against the environment, which require both legislative and organizational solutions, are identified, including the following: improvement of the existing methodology for calculating environmental damage caused to the environment as a result of hostilities; inclusion in the calculation of environmental damage caused to the environment as a result of hostilities, loss of the ability of the environment to provide ecosystem services; features of international cooperation in the protection of territories in the framework of active hostilities under the protection of international conventions. It is proved that the amount of damage due to the loss of the ability of the environment to provide goods and services (ecosystem services) should be taken into account when calculating environmental damage. The need for international cooperation of Ukraine, in particular with the Secretariat of the Ramsar Convention on the territories of wetlands under occupation, is substantiated by the fact that such a cooperation can help to obtain data from satellites concerning the current situation of wetlands to capture environmental changes that could be caused by activities of Russian Federation on the occupied territories. In view of the case law of the International Court of Justice, it is proposed to amend the bylaws on the calculation of environmental damage, taking into account the damage caused by the loss of the ability of the environment to provide ecosystem services. Ukraine is currently developing a legal framework that will contribute to the formation of a list of all violations in the field of environmental protection in connection with the armed aggression of the Russian Federation and a full calculation of environmental damage in Ukraine.
THE EXPEDIENCY OF THE FORENSIC EXPERT CRIMINAL LIABILITY FOR PROVIDING A DELIBERATELY FALSE OPINION AND FEATURES OF SUCH A CRIMINAL OFFENSE
Authors: Shunevych Kateryna , Fedorovych Nataliia
Published: August 2022

The expediency of establishing the forensic expert criminal liability for providing a deliberately false opinion and the features of such a criminal offense under Part 1 of Art. 384 of the Criminal Code of Ukraine are analyzed in the article. The necessity for norms providing for the liability of the forensic expert is stated, and the requirement for their actual application is pointed out. A criminally illegal act provided by Art. 384 of the Criminal Code of Ukraine is analyzed: Deliberately expert false opinion, which was made for submission or submitted to the body conducting pre-trial investigation, enforcement proceedings, court, High Council of Justice, temporary investigative or special temporary investigative commission of the Verkhovna Rada of Ukraine. Within the research, authors identify the main shortcomings of Art. 384 of the Criminal Code of Ukraine formulation. The researchers propose to amend the disposition of Art. 384 of the Criminal Code of Ukraine so that criminal liability of the forensic expert to draw a deliberately false opinion will exist regardless of the circumstances of such a criminal offense. The application of Art. 384 of the Criminal Code of Ukraine in terms of criminal liability of the expert liability for providing a deliberately false opinion is analyzed. The researchers find that there are no convictions that have entered into force in Ukraine to bring experts to justice under the relevant part of Art. 384 of the Criminal Code of Ukraine. Consequently, the researchers note that, despite the existence of certain shortcomings of this article of the Special Part of the Criminal Code of Ukraine, the main problem is the lack of its real application in practice. This means that public authorities do not prosecute experts for drawing deliberately false opinions. At the same time, the proper and effective application of criminal law will help experts to comply with their responsibilities. In addition, the suggestions on improving the sanction of Art. 384 of the Criminal Code of Ukraine are stated.
IN SILICO, TO DETERMINE THE ACTIVE COMPOUNDS OF BLACK TEA AND TURMERIC IN INCREASING THE ACTIVITY OF THE ENZYME SOD
Authors: Hasan Akhmad Endang Zainal , Safithri Mega , Huda Aziz Syamsul , Kurniasih Rini
Published: August 2022

Damage to cells caused by stress can be reduced by the presence of antioxidants, one of which is Superoxide dismutase (SOD). The role of the active ingredients of black tea and turmeric will be studied using the in-silico method to identify the active compounds as components in SOD activation. The bioavailability and toxicity of the active compounds of black tea and turmeric were studied and followed by molecular docking and virtual games. The parameters studied are Gibbs's free energy (∆G) and binding site similarity (BSS). The results were analyzed using Gibbs's free energy (∆G) and binding site similarity (BSS) parameters. It was found that those that could increase the activity of Cu/Zn SOD enzymes were Epicatechin gallate (black tea) and curcumin (turmeric), with values ​​of -9.5 and -7.4 Kcal/mol and the same BSS value of 81.8%. The control ligand used was beta amyrin. According to Lipinski's rules, Epicatechin gallate and curcumin compounds can be absorbed well and are safe for consumption. This study concludes that Epicatechin gallate, an active compound of black tea, and curcumin, an active compound of turmeric rhizome, have the best potential to increase the activity of Cu/Zn SOD enzymes based on the results of virtual screening and molecular docking. Epicatechin gallate and curcumin are predicted to be well absorbed by the body because they qualify Lipinski's rules and are not toxic and safe for consumption.
KOLABORASI FINTECH PERBANKAN DAN IMPLIKASI PADA UMKM HALAL DI INDONESIA
Authors: Sari Novi Primita
Published: August 2022

Keberadaan layanan fintech membuka peluang dan akses yang lebih besar pada layanan keuangan formal, sehingga hal ini akan mendorong pertumbuhan ekonomi serta pembangunan yang inklusif dan berkelanjutan. Penelitian ini bertujuan untuk mengurai bentuk kolaborasi yang dapat dilakukan dengan keberadaan Fintech pada UMKM dengan menggunakan analisis SWOT dan bantuan aplikasi N-Vivo khususnya UMKM Halal agar dapat diambil strategi lebih lanjut guna optimalisasi. Hasil penelitian menunjukkan bahwa masih banyak sekali peluang yang bisa dimanfaatkan guna memberikan keberlanjutan dan pengembangan sektor UMKM, diantaranya adalah kemudahan akses layanan keuangan dari segi pembiayaan dan pencarian serta penentuan supplier produk halal bagi mereka sehingga memberikan dampak yang besar bagi keberlanjutan UMKM. Sedangkan hal yang masih harus diperhatikan dalam penggunaan fintech adalah kemungkinan pencurian data dan kebijakan-kebijakan pemerintah untuk melindungi keamanan para pelaku UMKM yang menggunakan aplikasi teknologi keuangan digital (fintech).
IMPORTÂNCIA DA INSERÇÃO DA ODONTOLOGIA NA RESIDÊNCIA MULTIPROFISSIONAL DO HEMORIO
Authors: Duarte da Costa Mendes Vera Lúcia
Published: August 2022

O Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti – HEMORIO, é o Hemocentro coordenador do Estado do RJ responsável pelo abastecimento de sangue de cerca de 180 unidades de saúde pública conveniadas ao SUS, e pelo tratamento hematológico em nível primário à terciário de baixa a alta complexidade. A Instituição oferece uma formação diferenciada que qualifica profissionais para um olhar especializado sobre a produção de novos conhecimentos quanto ao processo saúde-doença, com atenção integral à saúde, nas respectivas áreas de atuação
Differential expression of LILRB3 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of LILRB3, encoding leukocyte immunoglobulin-like receptor B3, in primary fibroblasts of patients with sporadic ALS (SALS). LILRB3 transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Differential expression of POU5F1P4 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of POU5F1P4, encoding POU class 5 homeobox 1 pseudogene 4, in primary fibroblasts of patients with sporadic ALS (SALS). POU5F1P4 transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Photosensitive Accessibility for Interactive Data Visualizations
Authors: South Laura , Borkin Michelle
Published: August 2022

Accessibility guidelines place restrictions on the use of animations and interactivity on webpages to lessen the likelihood of webpages inadvertently producing sequences with flashes, patterns, or color changes that may trigger seizures for individuals with photosensitive epilepsy. Online data visualizations often incorporate elements of animation and interactivity to create a narrative, engage users, or encourage exploration. These design guidelines have been empirically validated by perceptual studies in visualization literature, but the impact of animation and interaction in visualizations on users with photosensitivity, who may experience seizures in response to certain visual stimuli, has not been considered. We systematically gathered and tested 1,132 interactive and animated visualizations for seizure-inducing risk using established methods and found that currently available methods for determining photosensitive risk are not reliable when evaluating interactive visualizations, as risk scores varied significantly based on the individual interacting with the visualization. To address this issue, we introduce a theoretical model defining the degree of control visualization designers have over three determinants of photosensitive risk in potentially seizure-inducing sequences: the size, frequency, and color of flashing content. Using an analysis of 375 visualizations hosted on bl.ocks.org, we created a theoretical model of photosensitive risk in visualizations by arranging the photosensitive risk determinants according to the degree of control visualization authors have over whether content exceeds photosensitive accessibility thresholds. We then use this model to propose a new method of testing for photosensitive risk that focuses on elements of visualizations that are subject to greater authorial control -- and are therefore more robust to variations in the individual user -- producing more reliable risk assessments than existing methods when applied to interactive visualizations. A full copy of this paper and all study materials are available at https://osf.io/8kzmg/.
Differential expression of COX20 in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding cytochrome c oxidase assembly factor COX20, COX20, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. COX20 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of COX20 in primary tumors of the breast was correlated with overall survival in patients with luminal B subtype and normal-like subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. COX20 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of CYB561 in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding cytochrome b561, CYB561, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. CYB561 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of patients survival data revealed that expression of CYB561 in primary tumors of the breast was correlated with overall survival in human breast cancer. CYB561 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Like friends, brain regions depend on each other to make good memories
Authors: Mindsponge AISDL
Published: August 2022

In order to execute a cognitive task, the mind needs to temporarily hold a certain amount of information necessary for dealing with said task, which is called working memory. But the neural mechanism of how the brain creates and keeps working memory remains unclear. Is the information stored through engrams located in one or multiple regions of the brain?A recent study published in Nature on mice revealed that their visual working memory is maintained by the interconnection between different brain regions. ***** For more information, please visit: https://mindsponge.info/posts/38 *****
Zeolite 13X as Analysis of Pressure Laboratory Scale Swing Adsorption (PSA) Varian Design using Adsorben Medium
Authors: karisman tobikul
Published: August 2022

Dengan menggunakan metode Quality Function Deployment (QFD), varian terbaik pada konsep desain Pressure Swing Adsorption (PSA) skala laboratorium (spesifikasi: kapasitas 2 – 2,5 kg, konsentrasi oksigen 82%, tekanan 20 Psi, laju alir 20 L/menit ) dengan media adsorben zeolit 13X adalah varian 10 karena memenuhi daftar spesifikasi karena varian yang digunakan pada alat PSA adalah tipe bed atau kolom. yang digunakan adalah single bed dengan kapasitas zeolit 13X 2 – 2,5 kg, mekanisme katup menggunakan manual sehingga tidak perlu menggunakan sistem kendali otomatis, sumber energi listrik adalah listrik PLN dan tidak memerlukan akumulator, dan tabung produk O2 menggunakan 1 tabung O2 sehingga lebih sederhana.
Manuscript (PREPRINT)
Authors: Buil Marieke , Kösters Mia P. , Koot Hans M.
Published: August 2022

Manuscript filesMeasurement and construct-level invariance of the Dutch Revised Child Anxiety and Depression Scale’s test scores (original version; RCADS) across gender and ethnic (minority) background of the four largest ethnic groups of children living in the Netherlands (i.e., native Dutch, 52% girls, SES = 0.41; Moroccan, 53% girls, SES = -1.66; Turkish, 49% girls, SES = -1.71; or Surinamese/Antillean 54% girls, SES = -1.65) was evaluated. Symptoms of generalized anxiety disorder, social phobia, separation anxiety disorder, panic disorder, obsessive-compulsive disorder and major depressive disorder were rated by 2,679 mainstream elementary schoolchildren (M age = 10.61). Results from discrete multiple-group confirmatory factor analyses showed that factor means were generally insensitive to potential gender bias. However, moderate violations of measurement invariance between native Dutch and the three ethnic minority groups were found for social phobia, panic disorder and separation anxiety disorder symptoms. Latent mean difference tests indicated that girls had higher mean levels on all RCADS subscales compared to boys. Furthermore, with a few exceptions, children from ethnic minority groups reported higher levels of symptoms of panic disorder, generalized anxiety disorder and obsessive-compulsive disorder compared to native Dutch children. No level differences between the four ethnic groups were found for symptoms of social phobia, major depressive disorder and separation anxiety disorder. Scores derived from the RCADS are largely comparable between elementary school boys and girls, but for three out of six subscales caution is warranted when comparing mean level differences of native Dutch children with children of Turkish, Moroccan and Surinamese/Antillean ethnic backgrounds.
Differential expression of SYNE4 in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding spectrin repeat-containing nuclear envelope family member 4, SYNE4, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. SYNE4 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of SYNE4 in primary tumors of the breast was correlated with distant metastasis-free survival in patients with luminal A subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. SYNE4 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of EZR in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of women with breast cancer. We found significant differential expression of the gene encoding ezrin, EZR, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 70 and higher, and in women aged 45 and younger. EZR mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of patient survival data revealed that expression of EZR in primary tumors of the breast was correlated with overall survival in human breast cancer. EZR may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of MYEF2 in cancers of the breast.
Authors: Mamoor Shahan
Published: August 2022

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with early-onset breast cancer. We found significant differential expression of the gene encoding myelin expression factor 2, MYEF2, when comparing primary tumors of the breast to the tissue of origin, the normal breast: in women aged 45 and younger, and women aged 70 and higher. MYEF2 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of MYEF2 in primary tumors of the breast was correlated with distant metastasis-free survival in patients with luminal B subtype breast cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by PAM50 molecular subtype. MYEF2 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Differential expression of KLF9 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: August 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of KLF9, encoding Kruppel-like factor 9, in primary fibroblasts of patients with sporadic ALS (SALS). KLF9 transcript was present at significantly lower levels in SALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of sporadic ALS.
Vision impairment puts the mind at risk
Authors: Mindsponge AISDL
Published: August 2022

Losing the ability to see seems to deeply affect the human mind. Studies have shown that older adults with vision impairment have a higher risk of cognitive impairment and dementia.