bluuebunny/crossref_metadata_2025 huggingface dataset:
PENDIDIKAN AKHLAK DALAM KELUARGA PADA REMAJA DI PASAR LATONG KABUPATEN PADANG LAWAS
Authors: Hasibuan Mahadir Muhammad
Published: January 2022

Abstrak Tujuan penelitian ini untuk mengetahui materi pendidikan akhlak, metode dan media pendidikan akhlak. dalam keluarga pada remaja di desa Pasar Latong Kecamatan Lubuk Barumun Kabupaten Padang Lawas. Adapun jenis penelitian ini adalah penelitian kualitatif dengan menggunakan analisis deskriptif dengan sumber data primer dan skunder melalui observasi, wawancara. Hasil penelitian ini menunjukkan materi pendidikan akhlak yang diberikan oleh orang tua pada remaja adalah materi tentang pendidikan akhlak kepada Allah, rasul, dan akhlak kepada manusia baik secara pribadi maupun hubungannya dengan masyarakat dan lingkungan. Metode pendidikan akhlak yang diterapkan adalah keteladanan, kisah alquran dan nabawiyah, targhib dan tarhib, metode mauizah. Sedangkan media pendidikan akhlak yang digunakan yakni media audio, dan media cetak seperti Alquran hadis dan buku-buku agama. Kata kunci: pendidikan; akhlak; remaja; pasar latong. Abstract The purpose of this study was to determine the material of moral education, methods, and media of moral education. in the family of adolescents in Pasar Latong Village, Lubuk Barumun District, Padang Lawas Regency. The type of this research is qualitative research using descriptive analysis with primary and secondary data sources through observation, interviews. The results of this study indicate that the moral education material given by parents to adolescents is material about moral education to God, apostles, and morals to humans both personally and in relation to society and the environment. The method of moral education applied is exemplary, the story of the Koran and Nabawiyah, targhib and tarhib, the mauizah method. While the moral education media used are audio media, and print media such as the Qur'an, hadith, and religious books. Keywords: education; moral; youth; pasar latong.
PENINGKATAN KREATIVITAS BELAJAR IPA DENGAN PENERAPAN PROJECR BASED LEARNIG
Authors: Hilda Lelya , Arafah Ghifari Raihan
Published: January 2022

AbstractStudents' thinking ability is still low, there is a lack of strategies, approaches or models used to improve high old thinking skills (HOTS), one of which can be used is the project base learning approach. This study aims to determine the use of the base learning project approach. This research was conducted with a quantitative approach with a quasi-experimental model, with an experimental class and a control class. The results showed the average control class was 65 and the experimental class was 80, and from the T test = -24,504 with a significance of 0.001 0.005. These results indicate that the hypothesis is accepted.Keywords: creative thinking; problem base learning; HOTS. AbstrakKemampuan berfikir kreatif siswa masih rendah kuragnya strategi, pendekatanb atau model yang digunkan untuk meningkatan kemampuan berfikir hight older thinking skill (HOTS), salah satu yang daapt digunakan adalah pendekatan project base learning Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan pendekatan projek base learning.  Penelitian ini dilakukan dengan pendekatan kuantitatif dengan model quasi eksperimen, dengan kelas eksperimen dan kelas kontrol.  Hasil penelitian menunjukkan rata-rata kelas kontrol 65 dan kelas eksperimen 80, dan dari uji T test =  -24.504 dengan signifikan 0.001 0.005.  Hasil ini menunjukkan bahwa hiptesis diterima.Kata kunci: berfikir kreatif;  problem base learning; HOTS.
MODEL PEMBERIAN HUKUMAN TERHADAP PESERTA DIDIK DI MADRASAH ALIYAH AL-AHLIYAH AL-ISLAMIYAH
Authors: Daulay Muhammad Roihan , Pulungan Husniah Ramadhani
Published: January 2022

Abtrak  This article aims to find out how the model of giving punishment to students at Madrasah Aliyah Al-Ahliyah Al-Islamiyah Aek Badak uses qualitative research methods using descriptive analysis. This research was conducted using interviews and observations of the principal, teachers, and pickets. This research is carried out first looking for data from informant sources to be managed, classified, analyzed and given improvements and conclusions to the results of data that have been collected and analyzed based on relevant previous research concepts. The results of the study show that every violation committed by students must be given educational punishments such as reading the Koran, memorizing the Koran outside class hours. This model of punishment can improve students' understanding of the Koran and ultimately students are able to continue to integrate with the Koran. Suggestions are given to all madrasah managers to apply an educational model of punishment. Keywords: punishment model; students; madrasah.  Abstract Artikel ini bertujuan untuk mengetahui bagaimana model pemberian hukuman terhadap peserta didik di Madrasah Aliyah Al-Ahliyah Al-Islamiyah Aek Badak dengan menggunakan metode penelitian kualitatif dengan menggunakan analisis yang bersifat deskrptif. Penelitian ini dilakukan dengan menggunakan wawancara dan observasi terhadap kepala madrasah, guru, dan piket. Penelotian ini dilakukan terlebih dahulu mencari data dari sumber informan untuk dikelola diklasifikasi, dianalisis serta diberikan penyempurnaan dan kesimpulan terhadap hasil-hasil data yang telah dikumpulkan dan dianalisis berdasarkan konsep penelitian terdahulu yang relepan. Hasil penelitian menjukkan bahwa setiap pelanggaran yang dilakukan oleh siswa harus diberikan hukuman yang mendidik seperti membaca Alquran, menghafal Alquran di luar jam pelajaran. Model hukuman seperti ini dapat meningkatkan pemahaman siswa terhadap Alquran dan akhirnya siswa mampu terus berintegrasi dengan Alquran. Saran-saran yang diberikan kepada semua pengelola madarasah untuk menerapkan model hukuman yang sifatnya mendidik. Kata kunci: model hukuman; peserta didik; madrasah
تصورات مجتمع بادنسدمبوان شمالية تجاه برنامج دراسة اللغة العربية، كلية التدريس وتدريب المعلمين في جامعة الإسلمية الحكومية بادنسدمبوان
Authors: Siregar Rahma Hayati , Nasution Ja’far
Published: January 2022

Program Studi Pendidikan Bahasa Arab  IAIN Padangsidimpuan sampai saat ini telah meluluskan mahasiswa, jadi sudah ada alumninya yang melanjutkan studi ke luar Sumatera.Adapun penelitian ini mengambil lokasi di Kecamatan Padangsidimpuan Utrara, Kota Padangsidimpuan. Adapun jenis dari penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif, yang mana penelitian kualitatif merupakan penelitian yang bermaksud untuk memahami fenomena tentang apa yang dialami oleh subjek penelitian dengan cara mendeskripsikan atau menggambarkan dalam bentuk kata-kata dan bahasa pada suatu konteks khusus yang alamiah dan dengan memanfaatkan berbagai metode alamiahKesan Masyarakat Padangsidimpuan Utara terhadap Program Studi Bahasa Arab Fakultas Tarbiyah dan Ilmu Keguruan  IAIN Padangsidimpuan sangat baik dimana Program Studi Bahasa Arab adalah Program Studi Menyelenggarakan pendidikan yang unggul yang dirancang untuk menghasilkan lulusan yang siap menjadi pendidik Bahasa Arab  di sekolah dan madrasah. Mendidik dan membina mahasiswa sehingga mampu mengembangkan potensi keilmuan di bidang Bahasa Arab  serta mengaplikasikannya secara kritis, objektif dan berakhlak mulia, sehingga tercipta sarjana Bahasa Arab  yang professional, bermoral akademis, dan berakhlak mulia. Pendapat Masyarakat Padangsidimpuan Utara terhadap Program Studi Bahasa Arab Fakultas Tarbiyah dan Ilmu Keguruan  IAIN Padangsidimpuan adalah  Program Studi Pendidikan Bahasa Arab  (PBA) harapannya menjadi pusat pengkajian dan pengembangan keilmuan serta pengajaran Bahasa Arab yang terdepan di lingkungan Perguruan Tinggi dalam menyiapkan tenaga pendidikan Bahasa Arab yang sesuai dengan tuntutan dan kebutuhan masyarakat Padangsidimpuan Utara.
استخدام الوسائل الصورة في تحسين مهارة كتابة اللغة العربية في مدرسة الثانوية الإسلامية الأهلية دار الاستقامة بادانج سيدمبوان
Authors: Baharuddin Ismail , Ningsih Surya
Published: January 2022

Keterampilan menulis merupakan keterampilan terakhir dari keterampilan berbahasa. Masalah utama dalam penelitian ini adalah bagaimana menumbuhkan minat siswa dalam pemjaran keterampilan menulis menggunakan sarana gambar. Tujuan dari penelitian ini adalah untuk meningkatkan minat siswa dalam pembelajaran keterampilan menulis dengan menggunakan media gambar. Metode yang digunakan dalam penelitian ini adalah penelitian tindakan kelas yang menggambarkan terjadinya hubungan sebab akibat dari suatu perlakuan dengan penjelasan tentang apa yang terjadi ketika perlakuan tersebut diberikan، dan menjelaskan seluruh proses dari awal pemberian perilaku hingga efek tindakan. Hasil dari penelitian ini adalah penggunaan sarana gambar untuk meningkatkan minat dan kemampuan siswa dalam pembelajaran keterampilan menulis. Hasil ini didasarkan pada siklus penelitian berikut; Hasil pra sesi 36%، siklus I 56%، dan siklus III 80%. Kesimpulan dari penelitian ini adalah minat siswa dalam mengajar keterampilan menulis dengan menggunakan sarana image promotion.
Dorsal Raphe Nucleus 5-HT Neurons: A New Target for Rewarding Regulation and Drug Addiction
Authors:   Tianjin Institute Of Environmental And Occupational Medicine, Fu Bo
Published: January 2022

In current paper, we reviewed the functional mechanisms of Dorsal Raphe Nucleus (DRN) 5-HT neurons in rewarding regulation and drug addiction in the level of molecular, neuron and neural circuits. Furtherly, we prospected that the DRN 5-HT neurons might be a new drug target for addiction treatment in future.
Evaluating Partnerships for Practice Change in the Prevention, Identification, and Treatment of Fetal Alcohol Spectrum Disorders
Authors:   1600 Research Boulevard, Sapru Saloni
Published: January 2022

In 2014, the Centers for Disease Control and Prevention funded a four-year partnership effort between university and health care professional associations (HCPAs) to reach health care providers (HCPs)
Innovación social y política de los colectivos mexicanos de estatus mixto en zonas metropolitanas de los Estados Unidos: buenas prácticas y nuevos retos durante la Covid-19
Authors: Cruz Lera Estefanía
Published: January 2022

En las grandes urbes de Estados Unidos, los migrantes mexicanos han diversificado sus perfiles dando lugar a comunidades de origen migrante que se caracterizan por su estatus mixto. Mediante la documentación de su trabajo organizacional y su activismo frente a causas locales, en este artículo se identifica dos grandes estrategias que éstos utilizan para enfrentar los retos de sus comunidades: campañas de innovación social y tácticas de incidencia política; la primera, relacionada con actividades de emprendimiento social para mejorar la vida cotidiana de sus miembros y empoderarlos socioeconómicamente; la segunda, asociada al consenso de demandas, la negociación comunitaria de estrategias colectivas, la vinculación con los programas públicos de la ciudad y la construcción de alianzas con actores políticos locales. Con base en el trabajo de campo realizado en zonas metropolitanas de EE.UU., que consistió en observación participante, entrevistas y etnografía digital durante la pandemia, se documentan las buenas prácticas de innovación social e incidencia política de los migrantes y se explican los cambios que enfrentaron a causa de la Covid-19.
Palabras clave: Estatus migratorio mixto, Innovación social, Incidencia política, Zonas metropolitanas
Designing Android learning media to improve problem-solving skills of ratio
Authors:   Department of Mathematics Education, Universitas Sarjanawiyata Tamansiswa, Yogyakarta, Indonesia, Verawati Anisa , Agustito Denik , Pusporini Widowati , Utami Wikan Budi , Widodo Sri Adi ,   Department of Mathematics Education, Universitas Sarjanawiyata Tamansiswa, Yogyakarta, Indonesia
Published: January 2022

This study aims to determine the process of developing android-based learning media on comparative material to improve mathematical problem-solving skills and find validation through android-based learning media to improve mathematical problem-solving abilities. This research was conducted through research and development, where this research refers to 4D development, which consists of four steps: define, design, develop, and disseminate. This research was carried out to develop measures due to restrictions on the activities of emergency communities affected by the COVID-19 pandemic; this is one of the limitations of this research. Researchers use documents such as curriculum to collect data at the define and design stages, while a validation sheet is used for the development stage. The data analysis technique used descriptive qualitative at the define and design stage, and the development stage uses quantitative descriptive analysis. The main finding in this research is the prototype of android learning media on ratio. The results showed that V Aiken obtained more than 0.750, so this media prototype can be used for the following research stage.
Effects of Natural Resource exploitation on CEMAC Countries Development: The Human Capital Channel
Authors:   Dschang School of Economics and Management, University of Dschang-Cameroon, Leroy Ghamsi Deffo Salomon , Donal Ajoumessi Houmpe , Véronique Demgne Pouokam , Ledoux Njoupouognigni Moussa
Published: January 2022

Purpose: The aim of this study is to determine the effect of the exploitation of natural resources on the development of CEMAC countries and to examine human capital as a transmission channel. Design/methodology/approach: In order to achieve our goal, we formulate a panel of 6 CEMAC countries over the period 2002-2018. This period of study is justified by the surge in the prices of natural resources in the market and also a fall of the prices of basic resources following two large exogenous shocks (subprime crisis and 2015 oil crisis). The estimation method use is the fixe effect, two stage least square and the Maximum likelihood with limited information. Findings: Of the estimation by the fixed-effect method show that natural resources abundance measured by: total rent, oil rent and forest rent has a negative effect on economic development. Likewise, human capital contributes to the transmission of these effects. The minimum education rate beyond which natural resources no longer have a negative effect on economic development, measured by the logarithm of GDP, is approximately 0.52, 0.51 and 0.48 respectively when we consider the total rent, the oil rent and the forest rent. This result is confirmed with the adoption of Maximum likelihood with limited information and the Two Stage Least Squared. Research limitations/implications: This study is limited in time and space. Moreover, the failure to take into account certain human capital or development variables. Originality/value: In the literature on the natural resources curse, the analysis of transmission channels in developing countries remains largely unexplored. The human capital component studied in this article is one of the first in the case of CEMAC countries. Also, we studied the effect of many resources, both renewable and non-renewable.
An Optimal Forecasting Method of Passenger Traffic in Greek Coastal Shipping
Authors:   Department of Business Administration & Tourism, Hellenic Mediterranean University, Heraklion, Greece, Sitzimis Ioannis
Published: January 2022

Purpose: The main goal of this study is to exact an optimal forecasting method by answering the research question: which is the best model for capturing short-term seasonal components of passenger traffic in Greek coastal shipping? Design/methodology/approach: There are not a lot of scientific efforts in forecasting passenger traffic in Greece. In order to fill this gap, we tried to find an optimal forecasting method, by comparing Box-Jenkins ARIMA, smoothing and decomposition methods. As Greek coastal shipping consists of several concentrated submarkets (lines) we remained in fourteen popular itineraries (including total passenger traffic). Taking into consideration the high seasonality and no stationarity that characterizes those routes we limited our analysis to Winter’s triple exponential smoothing, to time series decomposition method, to simple seasonal model and to seasonal ARIMA models. Findings: The analysis results show that in fourteen popular coastal routes Winters’ multiplicative method, simple seasonal model and decomposition multiplicative trend and seasonal model have the best integration to the time series data. No coastal line led to better results by seasonal Box-Jenkins ARIMA models. Research limitations/implications: The results should be treated with caution since COVID-19 pandemic does not allow safe conclusions for the forecasting period 2020-2022 in GCS. However, the forecasting results of the first quarter of 2020, when pandemic had not fully prevailed, gave encouraging results with little deviations between predicted and actual values. Originality/value: Greek coastal shipping is one of the biggest in Europe serving a large number of passengers and having a large part of the total shipping fleet. It plays an important role for Greek economy and society, as it connects the majority of inhabited islands to mainland. The finding of an optimal forecasting method of passenger traffic is very significant for both business and government policy. Decisions on the number of routes served by shipping companies, on ships by coastal line (number and size), on companies' pricing policy, on public service obligations, on state port infrastructure policy and on the amount of state funding for barren lines are typical examples.
The Economic Cost of ill Health due to Air Pollution: Evidence from Greece
Authors:   Department of Balkan, Slavic and Oriental Studies, University of Macedonia, Thessaloniki, Greece, Panteli Maria , Delipalla Sofia
Published: January 2022

Purpose: Air pollution and its adverse health effects result in an economic cost to society. Given that the burden of disease from air pollution is to a large extent preventable, estimation of the magnitude of its economic cost is important. We estimate the economic cost of the health impact from exposure to ground-level ozone, and ambient and household PM2.5 air pollution, as well as their joint effects, in Greece. Design/methodology/approach: We analyze the economic cost of the health impact from air pollution using the Cost-of-Illness (COI) as well as the Willingness to Pay (WTP) approach. Finding: Based on the COI approach, air pollution attributable diseases resulted in a total economic cost of €1.27 billion in 2019, or 0.68 percent of GDP. Under the WTP approach, mortality cost is significantly higher. Research limitations/implications: In spite of some standard methodological limitations, giving a monetary value to the burden of disease from air pollution highlights the significance of curbing air pollution, providing at the same time guidance in prioritizing among various competing policy objectives. Air pollution abatement interventions can yield significant benefits for global health and the economy. Originality/value: To the best of our knowledge, this is the first study estimating direct and indirect costs of air pollution-attributable health consequences in Greece, using the most recent data for all specific-cause mortality and morbidity outcomes. Employing two alternative methodologies, COI and WTP, we provide a lower and an upper bound of the economic cost of air pollution, respectively. The COI estimates provide a financial measure of the potential gains (by age and gender) if air pollution were to be extensively mitigated. The WTP estimates are a starting point in a cost-benefit analysis evaluating certain environmental regulation policies. Our results and their policy implications could be a guide to other economies with similar characteristics and comparable air pollution levels with those in Greece.
Ciberadicción y rendimiento académico en adolescentes del distrito de Mariscal Benavides, Amazonas, Perú. 2021
Authors: Huamán Guiop Emily , López Sánchez Victor Edwin , Tafur Fernández Jhasill
Published: January 2022

El objetivo de la investigación fue establecer el nivel de relación entre ciberadicción y rendimiento académico en adolescentes del distrito de Mariscal Benavides, provincia de Rodríguez de Mendoza, Amazonas, Perú, 2021, el enfoque fue cuantitativo, relacional. Se utilizó el muestreo no probabilístico por conveniencia, la muestra estuvo conformada por 21 adolescentes. Para la recolección de datos se utilizó como instrumento para la ciberadicción la “Escala de ciberadicción de Lima”, el cual presentó 11 ítems que evaluaron, características sintomatológicas y características funcionales. Para el rendimiento académico se utilizó la libreta de notas que contiene el promedio obtenido de los estudiantes por curso del año 2020 y para establecer la relación entre las variables se utilizó el coeficiente de correlación de Pearson. Los resultados mostraron que el 14.3% (3) de los adolescentes presenta un nivel bajo de ciberadicción y el 85.7% (18) un nivel moderado, mientras que en rendimiento académico el 52.4% (11) presenta un nivel regular y el 47.6% (10) presenta nivel excelente. Concluyendo que existe una correlación negativa moderada r= -0.366 entre ciberadicción y rendimiento académico.
Motivación para viajar y satisfacción turística en función de los estilos de personalidad
Authors:   Universidad de Oviedo (España), Moral Jiménez María de la Villa , García García María ,   Universidad de Oviedo (España)
Published: January 2022

Free time is growing and tourism is a way to spend it as leisure, which has various implications, some of which are purely psychosocial. Therefore, the tourism activity is a psychosocial phenomenon that is worth to study. The goal of the present work is to subject is to study the relationship between tourists personality, motivation and tourist satisfaction, as well as differences according to sex, age, and educational level in the aforementioned variables. The sample is made of 239 participants aged betweed 12 and 82 years (X = 33, DT = 15.6) who have completed the NEO -FFI Personality Inventory, together with the Visibility Motivation Scales and Tourist satisfaction. They have also indicated their priorities according to Pearce‘s tourism motivation model. Based on the results, it have been found relationships between some personality profiles, different motivations and tourist satisfaction. However, it were not found statiscally significant differences according to the level of studies class in tourism motivations, as well as no inter -gender differences in motivation or tourist satisfaction. It woud be interesting as a future prospect promote research in this field that links personality and tourist hebavior, according to its importance at the psychosocial level.
Efeitos da pandemia do Coronavírus (COVID-19) no setor turístico da região nordeste do Brasil
Authors:   Universidade Federal do Rio Grande do Norte (Brasil), Guardia Mabel Simone , Taveira Marcelo da Silva ,   Universidade Federal do Rio Grande do Norte (Brasil), França Rosana Silva de ,   Universidade Federal do Rio Grande do Norte (Brasil)
Published: January 2022

The aim of this study is to discuss the effects of the coronavirus pandemic (Covid -19) on the tourism sector in the Northeast of Brazil. It was collated from reliable national/international news reports and data taken from the online portals of the Brazilian Institute of Geography and Statistics, the Ministry of Tourism and the Ministry of Health, the World Health Organization and the Pan American Health Organization, together with references to the impact of the pandemic on the tourism economy, both from a quantitative and qualitative perspective. The research typology is descriptive and exploratory, endorsed by the information gathered and the use of specialized literature supporting the theoretical discussion and analysis of results. Among the main effects of the pandemic in the tourism sector, the study highlights: cancellation of major events; the shutdown and/ or closing of hotels, high number of layoffs in the region’s tourism sector, among others. It also shows some actions, measures and policies to readjust the activities in an attempt to contain the economic crisis within the tourism sector.
Turismo, desenvolvimento local e as festas religiosas de Natividade, Tocantins – Brasil
Authors:   Instituto Federal do Amapá (Brasil), Sousa Poliana Macedo de , Lopes Jose Rogério ,   Universidade Federal do Tocantins (Brasil)
Published: January 2022

This article presents the Festival of Divino Espírito Santo and the Pilgrimage of Senhor do Bonfim, the main religious festivals in Natividade, a city located in the state of Tocantins, Brazil as motivators of religious tourism in the region. The research also reports the current scenario of tourism policies implemented in the state of Tocantins for the region of Natividade, where presently there is no focus on religious tourism but only on ecotourism. It is understood that religious festivals move the local economy, tourism and a whole chain of services that end up bringing together many people in the region and that there is still time to outline a model of local development as an alternative for tourism in the region.
O panorama da Pós-graduação Stricto Sensu em Turismo no Brasil a partir do perfil docente
Authors:   Universidade de São Paulo (Brasil), Kalaoum Fausi , Lopes Mariana ,   Universidade de São Paulo (Brasil), Tomazin Mariana ,   Universidade de São Paulo (Brasil)
Published: January 2022

The aim of this article is to investigate the universe of stricto sensu postgraduate studies in Tourism in Brazil based on the courses currently offered and on the profile of professors in the scope of the programs to which they belong. The universe included 10 postgraduate programs in Tourism and related areas of the Brazilian territory, totaling the characterization of 131 professors. The research used a mixed approach, contemplating qualitative and quantitative aspects, in a complementary way. A bibliographic review on the theme was carried out in order to support the understanding of the historical path of postgraduate programs and the production of knowledge in the area, in Brazil. The data collection adopted a scanning attitude based on the information available on the Lattes Platform. For statistical analysis, SPSS statistics and Microsoft Excel software were used. For the qualitative analysis, the word cloud visual resource was used. This paper contributes to the debate of the relation between postgraduation and tourism scientific production in Brazil.
The Genesis of Contracts of Sale and Supply in the Russian Political and Legal System of the 9th - 18th Centuries
Authors: Danilov Y. B.
Published: January 2022

The article examines the genesis of the legal institutions of purchase and sale, sale and delivery in the Russian state in the context of historical conditions that influenced the formation and development of the triumvirate of the relevant contracts. The author of the article analyzes the objective prerequisites, significant changes in the social and economic life of the state, the complication of social relations, as a result of which all the considered agreements arose. The article identifies and investigates the political and legal processes associated with the further evolution of these institutions, as well as the factors that determined their content.
On the Question of the Role of Anti-Corruption Expertise in the Legislative Activity of the State
Authors: Razdieiakonova E. V.
Published: January 2022

The study on anti-corruption expertise as a measure of corruption prevention touches on only certain aspects of this topic. In the section of the article devoted to the essence of the effectiveness of anti-corruption expertise, it is noted that the purpose of using anti-corruption expertise is to exclude from the legal space legal norms that create opportunities for corruption, but there is no audit of the effectiveness of the application of this particular norm of corruption prevention. In the second part of the article, trends are analyzed that contribute to an increase in the effectiveness of anti-corruption expertise, and here the author relies on the advantages of public anti-corruption control. The scientific novelty of the study lies in the fact that it substantiates the need for an audit of the effectiveness of anti-corruption expertise - calculating the predicted result of reducing manifestations of corruption, which will indicate the real action of the institution of anti-corruption expertise. It also points to the need to increase the level of legal awareness of citizens by involving a wide range of people in conducting anti-corruption expertise. The scientific result of the study was the proposal for the need to change the requirements for persons wishing to obtain state accreditation as an independent expert for conducting anti-corruption expertise.
The Legal Status of Juveniles in the Sphere of Banking Activities (Problems of Theory and Practice)
Authors: Rabets A. M. , Khvatova M. A.
Published: January 2022

The article is devoted to the problems of minors' rights to enter into credit agreements and Bank Deposit agreements, as well as their solution in banking and judicial practice. The purpose of the study is to identify the maximum opportunities and limits for minors to exercise their subjective civil rights in the field of banking within the framework of their constitutional and civil legal capacity. A number of proposals are being made to improve civil and family legislation, as well as legislation on guardianship and guardianship. In particular, it is proposed amend parts 2 and 4 article 26 of the civil code, minors to provide entrepreneurs the right to independently make transactions related to business activities because of its state registration was made with the consent of their legal representatives. In part 4 of this article, it is proposed to indicate that the restriction of legal capacity also applies to the disposal of deposits in credit institutions made by minors in their own name. It is proposed to make additions to article 60 of the RF IC and art. 19 of the Federal law “on guardianship and guardianship”, specify the legal regime of the part of alimony that the payer has the right to transfer to an account opened in the name of a minor recipient of alimony, provide for circumstances in which the contribution can be issued in full or in part with the permission of the guardianship and guardianship authorities until the recipient of alimony reaches the age of majority.
VIEW FROM THE INSIDE. STRUCTURAL AND CONCEPTUAL DIMENSIONS OF IRANIAN MINIATURE PAINTING
Authors: Шукуров Ш.М.
Published: January 2022

В статье рассказывается о взаимоотношении текста и иллюстрации с новых позиций структурных связей между текстом и метатекстом (в данном случае рукописной миниатюры на территории Большого Ирана). Что же касается диаграмматологии, то она осуществляет переход от структурных сдвигов к концептуальным превращениям, от поверхностных перемещений к интериоризациям. Автор приходит к выводу о том, что художник стремится создать впечатление взгляда изнутри, чему способствует принципиальная разомкнутость изобразительных композиций, возможность выхода за пределы рамки миниатюры. Взгляд изнутри не принадлежит одному произвольно взятому персонажу, художник создает впечатление средоточенности и открытости вовне всей композиции.
The art and the city environment in the flow of life
Authors: Дуцев М.В.
Published: January 2022

Статья посвящена вопросам жизни искусства в актуальном городском контексте, где встречаются история, природа, культурные коды, традиции и обновленные эстетические мотивы современного общества потребления. Особое значение отводится проблемам памяти и воображения, театральности восприятия окружения и художественным формам средовой коммуникации. Рассматриваются примеры архитектурно-художественных экспериментов, использующих потенциал личного духовного опыта автора и адресата, естественные мотивы, сценические ходы и смелые интервенции в городское пространство.

The article is devoted to the art life issues in the actual urban context, where history, nature, cultural codes, traditions and updated aesthetic motives of modern consumer society meet. Particular importance is given to problems of memory and imagination, theatricality of perception of the environment and artistic forms of environmental communication. Examples of architectural and artistic experiments using the potential of the personal spiritual experience of the author and the addressee, natural motives, scenic moves and bold interventions in the urban space are considered.
Myocardial Ischaemia Secondary to Anomalous Aortic Origin of the Left Main Coronary Artery
Authors:   Department of Cardiology, Flinders Medical Centre, Bedford Park, Australia, J Eng-Frost , WK Choo ,   Department of Cardiology, Royal Darwin Hospital, Tiwi, Northern Territory, Australia
Published: January 2022

Coronary Artery Anomalies (CAAs) are a heterogenous group of congenital disorders with an increasing incidence. Affected patients may present with a spectrum of symptoms reflective of myocardial ischaemia, depending on blood flow through the anomalous coronary artery and therefore myocardial supply. We present a case of a positive echocardiographic stress test in a patient with significant cardiovascular disease risk factors, who was subsequently found to have anomalous origin of the left main coronary artery arising from the right coronary cusp and running a malignant course between the aorta and the main pulmonary trunk. She later underwent re-diversion of the left main coronary artery to the left coronary sinus, and autologous pericardial patch to remnant stump of LMCA with symptom resolution.
Flavonoids from Uvaria alba attenuate LPS-induced inflammatory responses by suppressing NF-κB activation in RAW 264.7 macrophages: In silico and in vitro perspectives
Authors: Notarte Kin Israel , Quimque Mark Tristan , Macaranas Imee , Khan Abbas , Pastrana Adriel , Villaflores Oliver , Arturo Hans Christian , Pilapil Delfin Yñigo , Tan Sophia Morgan , Wei Dong-Qing , Wenzel-Storjohann Arlette , Tasdemir Deniz , Choi Yung Hyun , Macabeo Allan Patrick
Published: January 2022

Hyperreactive inflammatory response occurs when there is excessive activation of NF-κB leading to a pathologic cascade of inflammatory reactions. Thus, we investigated the inflammatory modulating potentials of the Philippine medicinal endemic plant Uvaria alba. ELISA was initially performed to measure levels of proinflammatory mediators (NO and PGE 2 ) and cytokines (TNF-α, IL-1β and IL-6), followed by RT-PCR and western blotting to determine mRNA and protein expression, respectively. Using immunofluorescence staining combined with western blot analysis, the activation of NF-κB was further investigated. Putative flavonoids from the bioactive butanol subextract (UaB) were identified using high resolution LC-MS and subjected to in silico screening against COX-1/2, iNOS, TNF-α, TACE, and IKK via molecular docking and molecular dynamics simulations at 140 ns. UaB abrogated protein and mRNA expressions of iNOS, COX-2, TNF-α, IL-1β and IL-6 by suppressing the production of proinflammatory mediators and cytokines. Furthermore, UaB attenuated NF-κB activation by inhibiting the nuclear translocation of the transcription factor p65. LC-MS analysis with UaB revealed the presence of flavonol aglycones — quercetin (4) and kaempferol (6) — and their glycosylated derivatives — quercitrin (3), rutin (5), and kaempferol 3-O-rutinoside (7). Molecular docking analysis suggests that the major flavonol aglycones exhibited high affinity towards COX-2 NSAID-binding site, TNF-α and TACE, while the glycosylated flavonoids showed high affinity towards iNOS and IKK. The top protein-ligand complexes were found to be dynamically stable as shown by molecular dynamics simulations. This is the first report highlighting the mechanistic in silico and in vitro anti-inflammatory potential of U. alba.
N-glycosylation induced changes in tau protein dynamics reveal its role in tau misfolding and aggregation: A microsecond long molecular dynamics study
Authors: Mathew Alen T , Baidya Anurag TK , Das Bhanuranjan , Kumar Rajnish
Published: January 2022

Various post translational modifications like hyper phosphorylation, O-GlycNAcylation, and acetylation have been attributed to induce the abnormal folding in tau protein. Recent in vitro studies revealed the possible involvement of N–glycosylation of tau protein in the abnormal folding and tau aggregation. Hence in this study, we performed microsecond long all atom molecular dynamics simulation to gain insights into the effects of N-glycosylation on Asn-359residue which forms part of the microtubule binding region. Trajectory analysis of the stimulations coupled with essential dynamics and free energy landscape analysis suggested that tau, in its N-glycosylated form tend to exist in a largely folded conformation having high beta sheet propensity as compared to unmodified tau which exists in a large extended form with very less beta sheet propensity. Residue interaction network analysis of the lowest energy conformations further revealed that Phe378 and Lys353 are the functionally important residues in the peptide which helped in initiating the folding process and Phe378, Lys347&Lys370 helped maintaining the stability of the protein in the folded state.
Histological remission of ulcerative colitis with combined anti-cytokine and cell therapy
Authors: Knyazev Oleg V. , Khomeriki Sergey G. , Kagramanova Аnna V. , Lishchinskaya Albina A. , Smirnova Olga A. , Noskova Karina K. , Parfenov Asfold I.
Published: January 2022

Aim. To conduct comparative analysis of histological remission in patients with moderate and severe ulcerative colitis (UC), receiving biological therapy vedolizumab, mesenchymal stem cell (MSC) treatment and combined stem cells and vedolizumab therapy.
Materials and methods. We studied biopsies of 75 patients with total or left-sided moderate and severe ulcerative colitis, divided into groups depending on treatment. The first group of UC patients (n=29) received stem cell therapy 2 mln per kg; the second group of UC patients (n=27) received vedolizumab and the third group (n=19) MSC and vedolizumab. The efficacу of treatment was assessed by C reactive protein (CRP), Mayo score (MS), fecal calprotectin (FC) and Geboes score (GS).
Results. We determined medium correlation between basic FC and MS before treatment (r=0.6605, p0.05). After 12 weeks of treatment in the first group of UC patients (n=29) CRP was 7.82.1 mg/l, FC 409.344.85 g/g, medium GS 1.20.1 points. After 12 weeks of treatment in the second group of UC patients (n=27) CRP was 8.41.4 mg/l, FC 435.547.3 g/g, medium GS 1.350.15 points. After 12 weeks of treatment in the third group of UC patients (n=19) CRP was 6.41.1 mg/l, FC 290.617.5 g/g, medium GS 0.90.1 points. We proved strong direct relationship between FC and GS after 12 weeks of treatment in UC patients, receiving MSC (r=0.8392, p0.05). The statistically significant majority of patients, achieved histological remission, have less than 5-year duration of disease.
Conclusion. Our study showed that clinical and endoscopic remission in UC patients does not always correlate with histological remission. Combined anti-cytokine and stem cells therapy contributes to achieve deep remission and decrease mucosa inflammation rather than single MSC or vedolizumab treatment. Deep remission could be achieved by earlier start of biological therapy. FC could be a predictor and marker of mucosa healing and histological remission
Empagliflozin and heart failure: position paper of the experts on the results of the online meeting and discussion of the EMPEROR-Preserved Trial
Authors: Arutyunov Gregory P. , Lopatin Yuri M. , Ametov Aleksandr S. , Ageev Fail T. , Antsiferov Mikhail B. , Villevalde Svetlana V. , Vinogradova Nadezhda G. , Galstyan Gagik R. , Galyavich Albert S. , Gilyarevskiy Sergey R. , Glezer Maria G. , Zhirov Igor V. , Ilyin Mikhail V. , Lebedeva Anastasiya Iu. , Nedogoda Sergey M. , Salukhov Vladimir V. , Tarlovskaya Ekaterina I. , Tereshchenko Sergey N. , Fomin Igor V. , Khalimov Iurii Sh. , Khasanov Niaz R. , Cherkashin Dmitriy V. , Yakushin Sergey S.
Published: January 2022

At an international online expert meeting held on September 16, 2021, the results of the empagliflozin research program EMPA-REG Outcome, EMPEROR-Reduced and EMPEROR-Preserved were reviewed. We analyzed cardiovascular and renal outcomes during the treatment with empagliflozin in patients with chronic heart failure, regardless of the presence of type 2 diabetes mellitus. The positive results of the EMPEROR-Preserved study are updated and their significance for clinical practice is discussed. Several proposals have been adopted that will accelerate the introduction of empagliflozin therapy into practice in patients with heart failure and overcome clinical inertia.
Standard of living and quality of life
Authors: Shumilina Vera , SHEAA MUTHANA , Gerasimik Andrey
Published: January 2022

There are many terms that characterize and demonstrate the level and quality of life of the population by means of individual indicators. This article analyses and separates concepts such as 'standard of living', 'quality of life', and 'welfare of the population'. Their differences and similarities are demonstrated and dissected, as well as how they can affect society and their socio-economic development
UNEMPLOYMENT IN RUSSIA
Authors: Shumilina Vera , Tupakova Ksenia
Published: January 2022

In this article I will consider one of the critical problems in Russia - unemployment, which acts as a complex and controversial macroeconomic phenomenon of economic life. It exerts significant socio-economic pressure on society and affects political life in the country. That is why this problem is urgent and requires consideration
ANALYSIS OF UNEMPLOYMENT IN THE RUSSIAN LABOR MARKET: CAUSES AND CONSEQUENCES
Authors: Izvarina Nataliya , Kosyanok Anastasiya , Pashchenko Eduard
Published: January 2022

The article discusses the problems associated with unemployment in the Russian labor market. The analysis of unemployment indicators in Russia is carried out. The main reasons for the low level of employment of the population are systematized. The economic and non-economic consequences of this socio-economic phenomenon on both an individual and the economy of the country as a whole are presented
IMPACT OF THE INTERNET AND SOCIAL MEDIA ON YOUTH AS A THREAT TO PUBLIC SAFETY
Authors: Shumilina Vera , Srapyan Vlada
Published: January 2022

This article examines the impact of the internet and social media in terms of a platform for communication, information transfer, learning and its impact on young people. The topic of socialising people in social parts is analysed as one of the most important things in human life through immersion in virtual space
RELIGIOUS EXTREMISM AS A THREAT TO THE SECURITY OF MODERN RUSSIA
Authors: Shumilina Vera , Popov Daniil
Published: January 2022

The article deals with the problem of religious extremism in the ideological aspect of the threat to the security and stability of modern Russian society posed by the radical religious current "Wahhabism". On the basis of analysis of one of the most controversial religions - Islam - conclusions are made as to what methods should be undertaken to combat religious extremism
Socio-economic and legal problems of modern society
Authors: Shumilina Vera , Krokhicheva Galina , Sidorina Tat'yana , Izvarina Nataliya , Tsykora Anna , SHEAA MUTHANA , Brykalov Vitaliy , Lugantsev Anton , Ponomarenko Valeriya , Sim Igor , Talanina Veronika , Srapyan Vlada , Kosyanok Anastasiya , Tyapkina Violetta , Gerasimik Andrey , Tupakova Ksenia , Pashchenko Eduard , Volkov Egor , Kuzin Daniil , Popov Daniil , Kim Alexander , Chibizov Roman
Published: January 2022

The problems of the socio-economic development of Russia, as well as the problems associated with law enforcement that exist today, are associated with many factors that have their roots since the collapse of the Soviet Union, as well as a result of subsequent reforms, crises, total economic changes and other factors ... Currently, the pandemic is having a big impact.
In addition, the development of modern society is influenced by the processes of globalization and digitalization, which resulted in a reassessment of values, changes in education, culture, and legal aspects of society.
This monograph is a collective work of teachers and students of the Department of Economic Security, Accounting and Law of the Don State Technical University and the Department of Analysis of Economic Activity and Forecasting of the Rostov State Economic University (RINH).
It is devoted to the study of individual socio-economic and legal problems and processes.
Transformation of Audit Methodology with the Use of Blockchain and DLT Technologies
Authors: Bulyga R. P. , Safonova I. V.
Published: January 2022

The development of blockchain and distributed ledger technology (DLT) technologies stimulates diametrically opposite points of view about the prospects of traditional institutions in the digital economy: from their complete disappearance to a cardinal transformation. This matter also applies to the field of accounting and auditing. The purpose of the study is not only to identify trends in the transformation of the audit methodology but also in an accountant/auditor profession itself by using blockchain and DLT. The conduct of this research is based on the use of the following methods: analysis and synthesis, comparison, systemic and logical approach, analogies and grouping. The paper contains an overview of the implementation practice of blockchain technology by the Big Four audit companies, as well as the composition of the main developers and the software products they offer based on the blockchain technology and DLT used in audit activities. There have been identified the key trends in the development of an accountant/auditor professions in connection with the use of blockchain technology and DLT. The conclusion is made about the need for a significant transformation of the audit methodology, as well as the profession of an accountant/auditor in connection with the use of blockchain and DLT, but it is not about replacing the audit institution with these technologies. The authors have formulated proposals and defined the most significant innovations of the classical methodology for conducting an audit of the business processes effectiveness based on the use of blockchain technology and DLT.