bluuebunny/crossref_metadata_2025 huggingface dataset:
Prohibition of Price Discrimination Practice Under Law No. 5 Of 1999 On Prohibition of Monopoly Practices and Unhealthy Business Competition
Authors: Prajatama Hangga
Published: February 2021

In the business world, business competition or competence among business people in seizing the market is very reasonable. However, this becomes unnatural when the competition is carried out in an unfair manner, with the aim of preventing other business actors from competing (barrier to entry) or shutting down competitors' businesses. One form of anti unfair competition carried out by business actors in creating market power has been anticipated in Law Number 5 of 1999, namely the existence of price discrimination. The research method used is normative juridical, namely legal research that emphasizes the review of legal documents and library materials related to the subject matter. Based on the research that has been done, there is an Article that Regulates Regarding Price Discrimination in Law Number 5 of 1999 concerning Prohibition of Monopolistic Practices and Unfair Business Competition, which is located in Article 6 which states that business actors are prohibited from making agreements that cause one buyer to pay a price that is different from the price that must be paid by other buyers for the same goods and / or services. and the Guidelines for the Business Competition Supervisory Commission on Implementation Provisions in Article 6 of Act Number 5 of 1999 concerning Prohibition of Monopolistic Practices and Unfair Business Competition.Keywords: Prohibition, Price Discrimination, Law No. 5 of 1999.
Juridical Review of The Provision of Catering Services In Theory And Practice And Problematic at PT. Well Harvest Winning Alumina Refenery Site Kendawangan, Ketapang Regency, West Kalimantan
Authors: Putri Limas Mentari
Published: February 2021

Traditional Covenant Law theory has characteristics emphasizing the importance of legal certainty and predictability.  The main function of one of the contracts is to provide certainty about the binding of an agreement between the parties so that the principles of good faith in the civil law system and promissory estoppel in the common law legal system. which in this article the author will discuss PT ADEN's contractual agreement with PT Well Harvest Winning Refinery Alumina in the catering contract for employees of PT Well Harvest Winning Alumina Refinery which discusses whether the agreement made between the customer and the catering party has qualified the validity of the agreement and the issues contained in the valid agreement.Keywords: Treaty Law Theory, Civil Law, Agreement.
Free Notariatan Legal Services For The Community Are Not Able To Under The Law of Notary Office and Code Of Conduct and Its Application In Cilacap Regency
Authors: Mayasari Putri
Published: February 2021

Notarial Legal Services for free to people cannot afford is one of the notary obligations which regulated in the Statute and Notary Code of Ethics, even tough most people assume that people who use Notary services are usually those who are financially capable, so it is very rare to find anyone not able to ask for free notary services, but the rule still exists and until now there has been no further explanation about the limits and procedures for its application, so giving rise to different comprehension in each of the Notaries, likewise happen in Cilacap Regency. Need to know wheter the regulation has comply the purposive of the law and the application of the regulation in Cilacap Regency. Study with the legal research with the statute approach and conceptual approach then analyzed qualitatively. The government should be able to immediately make implementing regulations from these provisions, the organization should also be more aggressive in socializing. This rule is expected to be applied to the deed of establishment of business entities in accordance with government programs.Keywords: Free Notariatan Legal Services, Notaries
Application and Implications of Setting Up A Power of Attorney Form To Impose Dependent Rights (SKMHT) Made In Front of Notaries In Banyumas Regency
Authors: Wulandari Lita
Published: February 2021

The Form of Power of Attorney to Impose Dependent Rights (SKMHT) made by notary deed is stipulated in Article 96 paragraph (1) of the Head Regulation of the National Land Agency No. 8 of 2012 and Article 38 of the Law of the Notary Department No. 2 of 2014. This research aims to analyze the arrangements on the form of SKMHT made before notaries and to analyze the application and implications of SKMHT form arrangements made before notaries in the Banyumas Regency. This research uses normative juridical research methods with a statute approach and conceptual approach. The result of the research obtained is that the form of SKMHT with the proper notarial deed is as stipulated in Article 38 UUJN number 2 of 2014.  Violation of the provision causes the notary deed to be degraded as a deed under hand (Article 41 UUJN No. 2 of 2014) and implicates its dependent rights to be invalid so that the creditor does not have a position of priority or precedence to the holder (Droit de preference).Keywords: Notary Deed, Power of Attorney Imposing Mortgage Rights (SKMHT), Mortgage Rights
The Relevance of The Notarial Deed To The Deed of The Treatise of The Auction Made by The Notary As Class Ii Auction Officials
Authors: Permata Nezsa Agyu
Published: February 2021

The minutes of auction are the minutes of the auction made by the Bidding Officer which is an authentic. Deed and has perferct legal force (Explanation of Article 1 number 35 of the Minister of Finance Regulation Number 27/PMK.06/2016 concerning Bidding Immplementation Guidelines). Based on Article 15 paragraph (2) letter g of Law number 2 of 2014 concerning Position of Notary. It is explained that making the minutes of auction treaty is one of the Notary’s authorities. This means it cant be interpreted that the Auction Officer to make minutes of aution treaty. But in the implementation of the drafting of the minutes of auction there are 2 (two) ruless governing, namely the Notary, while the Auction Officer uses the Vendu Reglement reference, Stbl 1908:289, and in fact not all the Notary can make the auction treatise deed in accordance with the contents of the article, so that question artise regarding the auction treatise deed and the authentic deed make by the Notary the main issue raised in this study is how is the implementation of the authority of the Notary Public as a Class II Auction Officer in conducting the auction? And how is the relevance of the minute of the auction treaty with the Notary Public as Class II Auction Officer? Based on the result of research and conclusions that the Notary who made the auction treatise deed is the Notary in his capacity as a Class II Auction Officer who has followed the appointment process as a Class II Auction Officer, so that for the minutes of the auction tretise produced by a Notary Public in this case as a Class II Auction Officer, likened to authentic deeds as authetic deeds make by a Notaries. In the case  of the making of the minutes of the auction treaty, a Notary who serves as a Class II Auction Officer needs to strongly apply the precautionary principle in making the minutes of the aution treaty, because the existing rules do not accommodate the possition of a Notary who serves as a Class II Auction Officer. Keywords: Deed of Minutes of Auction, Notary Public, Class II Auction Officer.
Functionalization of E-Court System in Eradicating Judicial Corruption at The Level of Administrative Management
Authors: Iqbal Muhamad Iqbal , Susanto Susanto , Sutoro Moh
Published: February 2021

This study aims to determine the effectiveness of the implementation of E-Court to eradicate the activities of judicial corruption. Corruption in the administration sector is closely related to the relationship between justice seekers and court administration staff. The problems raised in this study are how functionalization of E-Court in eradicating judicial corruption in administrative management of cases in the courts in JABODETABEK and how to reform the management of administrative court in the future. This study uses an empirical method approach with descriptive analytical research specifications. This is because this research seeks to illustrate the facts of the effectiveness of the e-court system in eradicating corruption in the court administrative management sector. This concept of public service must be well understood by the judiciary. The functionalization of e-court is considered not optimal since many justice seekers do not know the existence and usefulness of the system. It is expected that the e-court system will support the establishment of the principle of quick, simple and low cost justice in the administrative management of cases. Keywords: E-Court, Court Administrative System, Corruption
The Implementation of Inheritance Based on The Tribe of Kaili Ledo and Islamic Inheritance Laws
Authors: Luawo Fipy Rizky Amalia , Amalia Haswida
Published: February 2021

Law is an inherent part of Indonesian society, which does not only national law but also customary law. One of the customary laws in Indonesia is the Kaili customary law. Kaili customary law is only applicable to specific communities. Whereas Islamic law applies broadly to all Muslims. One of them is in the field of inheritance law. From many disputes that occur in inheritance law, the distribution of heritage in inheritance law has always been a major problem that occurs in society, both in Kaili's customary inheritance and Islamic inheritance laws. It is interesting to find out more that each of the rules has different dispute resolution where Kaili‘s customary inheritance law trusts Totua nu ada as a person who has the capability to distribute the heritage. This study was conducted by the Conceptual and Comparative Approach. In conclusion, Kaili indigenous community, are familiar with customary institutions, and, in Islamic law, they have the Religious Courts to resolve their inheritance disputes. Keywords: Customary Inheritance law, Islamic Law, Division of inheritance
The Implementation of Regional Regulation of Kupang City Number 7 of 2000 Concerning Green Open Space in The Environmental Development of Kupang City
Authors: Se Bartholomeus Mbe , Pello Jimmy , Johanes Saryono
Published: February 2021

One of the important aspects in environmental development is the use of green open space that serves its objectives and functions. Therefore, the Kupang City Regulation Number 7 of 2000 as a legal guarantee in the use of green open space was issued. The legal issue being studied is whether the implementation the Kupang City regional regulation Number 7 of 2000 is in line with the purpose and function. The research is an empirical research. The results of the study found that implementation of Kupang City Regulation Number 7 of 2000  has not served its purpose and function. It was caused by various factors, as law enforcement officials factor and inadequate supporting facilities and infrastructure. Therefore, it was recommended that there should be seriousness in preparing both supporting facilities and infrastructure for the implementation of these local regulations. Keywords: The Implementation Of There Is A Regional Regulation; The Construction Of The Environment; Green Open Space
The Impact of Indonesian Law No. 6/2014 on Women’s Political Participation in the Politics of Kelurahan: A Study on Kelurahan’s Community Empowerment Institution (LPMK) in Salatiga, Indonesia
Authors: Purwanti Ani , Wijaningsih Dyah , Setiawan Fajar Ahmad
Published: February 2021

In Indonesia, decentralization and democratization have prompted the issue of women’s representation to be brought upon local and small-scale communities. One of the examples is the Indonesian Law No.6/2014 (the Village Act) in which the affirmative action for women’s participation is mandated in village’s representative body. Later, the same action is implemented in the urban counterpart to village’s rural that is Kelurahan, with the same Act –mutatis mutandis-. This article explores the implementation of Law No. 6/2014’s affirmative action to the kelurahan’s representative body, the Community Empowerment Institution or Lembaga Pemberdayaan Masyarakat Kelurahan (LPMK) in Salatiga. Acknowledging that there are fundamental differences between village and kelurahan, we found that such a maneuver has caused policy and practical inconsistencies where gender equality clause is omitted and the organization’s structure remains unreformed. Thus, it seems that the implementation of affirmative action for women participation in kelurahan’s politics has been withered before blooming.
The Legal Impacts of The Convention for The Conservation of Southern Bluefin Tuna on The Optimum Utilization and Sustainability of Highly Migratory Fish
Authors: Wartini Sri
Published: February 2021

The sustainability of southern Bluefin tuna (SBT) is very important, since the SBT as one of the highly migratory fish which is very valuable. Because of that, the SBT are exploited tremendously  and it caused serious  decline of the population. Due to the reasons, the aim of the paper is to examine comprehensively the legal impacts of the Convention for The Conservation of Southern Bluefin Tuna (CCSBT) on the optimum utilization and sustainability of the SBT as one of  highly migratory fish, There are two problems questions that  are proposed, namely,  first, how is the role of the Commission of CCSBT in the optimum utilization and sustainable conservation of the SBT. Second, how is the legal impacts of the CCSBT to the conduct of the Member States to obey the obligations of the CCSBT in order to utilize and  to maintain the sustainability of  the SBT in sustainable manner. The result of the paper finds that there is positive legal impacts of the CCSBT to the Member States’ conduct in order to materialize the  optimum utilization and sustainability of the SBT, though, there are still some challenges.   Keywords: conservation, highly migratory fish, optimum utilization, southern tuna Bluefin, sustainable manner.Southern Bluefin Tuna (SBT), as one of the highly migratory fish, is very valuable due to the high demand inthe international market. Hence, the SBT is exploited tremendously and it caused a severe decline in thepopulation. To maintain the sustainability utilization of SBT, the role of the Commission on the CCSBT isimperative. The objective of the research is to examine conceptually the legal impacts of the Convention forthe Conservation of Southern Bluefin Tuna (CCSBT) on the optimum utilization and sustainability of the SBT.It is a normative juridical research by applying conceptual and statutory approaches. The results of theresearch indicates that: first, the role of the Commission of CCSBT in the optimum utilization and thesustainability of the SBT is very significant: second, there are positive legal impacts of the CCSBT to theconduct of the Member States to comply with provisions of the CCSBT; third, the legal impacts of CCSBT areable to oblige the Member States to perform their obligations, however, there are still some challenges tomaterialize the objective of the CCSBT.Keywords: conservation; highly migratory fish; optimum utilization; southern tuna bluefin; sustainability.
A Remunicipalization Idea on Water Management in DKI Jakarta Province
Authors: Setiadi Wicipto , Pratiwiningrum Aprilia Zul
Published: February 2021

Since 1997, water privatization has existed but there is no significant progress on water management in Jakarta. Many households don’t have access to clean water due to the leakage and outdated pipes as well as the non-legal contract between PT. Aetra Air Jakarta and PT. Palyja. The contract was not in accordance with Article 33 (3) of the 1945 Constitution of the Republic of Indonesia and not in a fair tender. The research problems focus on: what actions are taken by theJakarta Government to take over the water management in Jakarta and Can theremunicipalization policy be used as a model in Jakarta? This research uses thenormative legal method. In order to address the issue, the Jakarta Governmentapplies the remunicipalization on water management. The government hasassigned the task force to find the ideal solution. The task force comes up with 3alternatives: status quo, contract termination, processed to the civil court.Keywords: Remunicipalization; DKI Jakarta Province; Water Privatization.
Reconstruction of Over-the-Counter Transaction Settings Based on Legal Certainty
Authors: Hamijaya J I Wayan Surya
Published: February 2021

OTC (Over-the-Counter) Transaction has become one of the alternative choices that greatly benefits to the parties. Problems then arise when the law has been formed by the competent authority, but it creates legal uncertainty due to the regulations that regulate the same things but different contents. The OTC Transactions are regulated in Financial Services Authority Regulation Number 22 / POJK.04 / 2019 on Securities Transactions. It is stated that the OTC are included in securities transactions, of which transactions can be done both in the primary and secondary markets. However, the Regulation Number 8 of 1995 does not regulate the OTC transactions. This can lead to the legal uncertainty towards the OTC transaction agents since there are more than one regulation governing the same problem. In addition, a reconstruction is needed for legal protection and dispute resolution related to the OTC transactions.Keywords: OTC transactions, regulatory reconstruction, legal certainty.
ANALISIS FAKTOR-FAKTOR YANG BERPENGARUH TERHADAP KINERJA PEGAWAI PT. KERETA API INDONESIA (PERSERO) DAOP 5 PURWOKERTO DENGAN PARTIAL LEAST SQUARE
Authors: Jajang Jajang , Supriyanto Supriyanto , Putra Dimas Eka
Published: February 2021

In this research, PLS method is applied to analyze which factor are affect employee performance in PT. Kereta Api Indonesia (Persero) DAOP 5 Purwokerto based on variables that are research factors that is employee performance, work motivation, leadership, training, work enviroment and corporate culture through the indicator which are then analyzed. From analysis using a PLS method with 6 variables of research, it was found that R-square value work of motivation variables of 77,00% with good assessments defined by  construct variable of leadership, training, work enviroment and corporate culture while another 23% is described by other variables outside this research. The value of R-square on employee performance variables of 66,00% with good enough assessment criteria described by the work of motivation, where as another 34% is described by other variables outside this research model.
Triterpenes and Phenolic Compounds From the Fungus Fuscoporia torulosa: Isolation, Structure Determination and Biological Activity
Authors: Béni Zoltán , Dékány Miklós , Sárközy András , Kincses Annamáris , Spengler Gabriella , Papp Viktor , Hohmann Judit , Ványolós Attila
Published: February 2021

Investigation of the methanol extract of the poroid fungus Fuscoporia torulosa resulted in the isolation of a novel triterpene, fuscoporic acid (1) together with inoscavin A and its previously undescribed Z isomer (2 and 3), 3,4-dihydroxy-benzaldehide (4), osmundacetone (5), senexdiolic acid (6), natalic acid (7), and ergosta-7,22-diene-3-one (8). The structures of fungal compounds were determined on the basis of NMR and MS spectroscopic analysis, as well as molecular modelling studies. Compounds 1, 6-8 were examined for their antibacterial properties on resistant clinical isolates, and cytotoxic activity on human colon adenocarcinoma cell lines. Compound 8 was effective against Colo 205 (IC50 11.65±1.67 µM), Colo 320 (IC50 8.43±1.1 µM) and MRC-5 (IC50 7.92±1.42 µM) cell lines. Potentially synergistic relationship was investigated between 8 and doxorubicin, which revealed a synergism between the examined compounds with a combination index (CI) at the 50% growth inhibition dose (ED50) of 0.521±0.15. Several compounds (1, and 6-8) were tested for P‐glycoprotein modulatory effect in Colo 320 resistant cancer cells, but none of the compounds proved to be effective in this assay. Fungal metabolites 2-5 were evaluated for their antioxidant activity using the oxygen radical absorbance capacity (ORAC) and DPPH assays. Compounds 4 and 5 proved to possess considerable antioxidant effect with EC50 0.25±0.01 (DPPH) and 12.20±0.92 mmol TE/g (ORAC). The current article provides valuable information on both chemical and pharmacological profiles of Fuscoporia torulosa, paving the way for future studies with this species.
A Study of Strengthening the DNA Business as well as Priorities of Policies in the Case of South Korea
Authors: Kim Yonghee , Kwak Jeongho
Published: February 2021

Recently, with the rapid advancement of the 4th Industrial Revolution, there has been a continuous outlook that Data (D), Network (N), and Artificial Intelligence (A) should be heavily utilized as resources in light of new value. South Korea is preparing policy training plans the likes of 5G network enhancement, AI manpower training, and data openings, etc., recognizing DNA technology as the key driving force behind the 4th Industrial Revolution and 5G network enhancement, AI manpower training, and data opening, etc. However, there is a criticism that the DNA industry remains in an early stage. Despite policy support within South Korea, the DNA industry has not been revitalized due to various causes, and in particular, not being concentrated on limited resources selectively is also pointed to as an important cause. this study would quantitatively draw the priority of policy measures as well as propose policy implications for the revitalization of the DNA industry by means of the ISM-ANP model. It is judged that South Korea’s experience in this way will be an important lesson for other countries which would politically promote the DNA industry as a new growth engine within the 4th Industrial Revolution environment.
Universally Available Innate and Adaptive Immune Cell Counts in Acute Ischemic Stroke (AIS) in the Context of Shared Pathobiology with COVID-19; Scoping Review
Authors: Wijeratne Tissa , Sales Carmela , Menon Rohit , Karimi Leila , Jakovljevic Mihajlo
Published: February 2021

Stroke is one of the leading cause of adult disability and the second leading cause of death worldwide. The immune system actively participates in the pathobiological process of AIS, during the index event and during the repair process despite the limited attention drawn to this aspect in the existing stroke guidelines globally. The similar clinical course and similar circulating innate and adaptive immune cell counts in AIS and COVID-19 has created a renewed interest in these easily available biomarkers innate and adaptive immunological changes in AIS with potential diagnostic, prognostic, and therapeutic implications. The current scoping review aimed to assess the significance of circulating neutrophil and lymphocyte counts and their ratio (NLR) in AIS and explore their association with post-stroke recovery trajectory. The Arksey and O'Malley methodological framework was employed to review the published papers on the neutrophil-lymphocyte ratio (NLR) and AIS in late November 2020. Only studies published in English from 2000-2020 were included in this scoping review. Fifty-three published papers were reviewed. This review's key finding is that a canonical inflammatory response occurs in AIS just as in the case of COVID-19 and neurological involvements well described in the recent literature. An excessive circulating innate immune cells (neutrophils) and reduced circulating adaptive immune cells (lymphocytes ) are associated with poorer outcomes during the acute interventions ( reperfusion therapies) as well as the recovery trajectory. Main representatives of innate and adaptive immunity follow a canonical course in AIS and COVID-19. Exaggerated circulating innate ( elevated neutrophils and elevated NLR) and reduced adaptive immune response (lymphopenia) correlate with the worse outcome in AIS and COVID-19. This scoping review's findings make the strongest case for a systems biology-based approach to the standard operating procedures in stroke care urgently.
Understanding the Role of Tacit Knowledge in Call-Center Organizations
Authors: Okegbe Samantha
Published: February 2021

This article aims to understand the role of tacit knowledge in call center organizations with the objective of understanding how call center representatives use tacit knowledge in their job roles and functions. Extant literature has focused on explicit knowledge but the research on tacit knowledge is still underdeveloped. The complexities and difficulties of the call center job role and the usage and transfer of knowledge is reviewed. Also, it takes into considerations past literature on tacit knowledge, how these respondents employ tacit knowledge in efficiently handling customers, responding to their queries, and engaging this form of knowledge in problem solving. The article concludes with discussion and implications for call center organizations and responders.
Characterisation of Immune Cell Subsets of Tumour Infiltrating Lymphocytes in Brain Metastases
Authors: Croft Priyakshi Kalita-de , Chittoory Haarika , Nguyen Tam , Saunus Jodi , Gyeong Kim Woo , McCart Reed Amy , Lim Malcolm , De Luca Xavier , Ferguson Kaltin , Niland Colleen , Mazzieri Roberta , Dolcetti Riccardo , Simpson Peter , Lakhani Sunil R
Published: February 2021

The heterogeneity of tumor infiltrating lymphocytes is not well characterized in brain metastasis. To address this, we performed a targeted analysis of immune cell subsets in brain metastasis tissues to test which immunosuppressive routes are involved in brain metastasis. We performed multiplex immunofluorescence (mIF), using commercially available validated antibodies on twenty formalin-fixed paraffin embedded whole sections. We quantitated the subsets of immune cells utilizing a targeted panel of proteins including PanCK, CD8, CD4, VISTA and Iba1, and analyzed an average of 15000 cells per sample. We classified tumours as either high (>30%) or low (<30%) tumour infiltrating lymphocytes (TILs) and found that increased TILs density correlated with survival. We next sought out to phenotype these TILs using mIF. The tumours with low TILs (n=9) had significantly higher expression of the immune-checkpoint molecule VISTA in tumor cells (p<0.01) as well as in their microenvironment (p<0.001). Contrastingly, the brain metastatic tumours with high TILs (n=8) displayed higher levels of activated microglia, as measured by Iba1 expression. Low TILs-tumours displayed CD8+ T-cells that co-express VISTA (p<0.01) significantly more compared to high TILs group, where CD8+ T-cells significantly co-express Iba1 (p<0.05). Interestingly, no definite phenotypes of CD4+ subsets were observed. These results were supported by RNA analysis of a publicly available, independent cohort. In conclusion, our work contributes to a growing understanding of the immune surveillance escape routes active in brain metastasis.
Category-Theoretic Formulation of Model-Based Systems Architecting: The Concept-Model-Graph-View-Concept Transformation Cycle
Authors: Mordecai Yaniv , Fairbanks James , Crawley Edward
Published: February 2021

We introduce the Concept-Model-Graph-View-Concept (CMGVC) transformation cycle. The CMGVC cycle facilitates coherent architecture analysis, reasoning, insight, and decision-making based on conceptual models that are transformed into a common, robust graph data structure (GDS). The GDS is then transformed into multiple views on the model, which inform stakeholders in various ways. This GDS-based approach decouples the view from the model and constitutes a powerful enhancement of model-based systems engineering (MBSE). CMGVC applies the rigorous foundations of Category Theory, a mathematical framework of representations and transformations. The CMGVC architecture is superior to direct transformations and language-coupled common representations. We demonstrate the CMGVC cycle to transform a conceptual system architecture model built with the Object Process Modeling Language (OPM) into dual graphs and a decision support matrix (DSM) that stimulates system architecture insight.
Education institution activity for student’s language rights and ethno-cultural needs
Authors: Terentyeva Irina , Fedorova Svetlana , Fahrutdinova Guzaliya , Iksanova Lidiya , Fakhrutdinova Anastasia
Published: February 2021

The study considers the problem of management process of an educational institution activity to meet the language rights and ethno-cultural needs of students. The relevance of the research is due to the lack of problem development and the lack of an effective model for managing the educational process to ensure the language rights and ethno-cultural needs of students. The respondents of the study were the students of National presidential boarding school, where a management model of an educational organization activity was created and tested. Firstly, the initial level of formation of teachers’ readiness for educational activity to meet the language rights and ethno-cultural needs of students in a boarding school for gifted children was revealed. Various diagnostic methods were used to specify the components of teachers’ readiness to teach children to meet the language rights and ethno-cultural needs. The original results are presented in the study and show dynamics after the implementation of the developed management model of an educational organization activity to meet the language rights and ethno-cultural needs of students. The model can be implemented in different educational organizations.
Professionally-oriented tasks in the formation of competencies in the field of students’ research activities
Authors: Kireeva Yulia Alexandrovna
Published: February 2021

Due to the introduction and implementation of the requirements of the third-generation Federal State Educational Standards, the importance of students' involvement in research activities during their studies has increased. Currently, special importance in the higher education system is given to the issues related to the organization of such work with students. Having mastered the principal educational program, graduates should be ready to carry out professional activities in the field of applied research, as well as to solve various research tasks. To do this, the graduates must have a certain set of competencies, formed in various ways and methods in the course of professional training. One of the best ways to form competencies both in the field of future profession and research activities is professionally-oriented tasks. As a rule, such tasks are offered to students starting from the first year. Gradually, the level of complexity of the tasks increases, and to solve such tasks, senior-year students need knowledge across multiple disciplines. The article presents a list of academic disciplines, whose study using various forms can train and develop various competencies, including research ones. Universities regularly involve students in research work. However, at present, an appropriate pedagogically sound system of continuous involvement of students in this work is required.
Human capital development: development of professional competencies through soft skills
Authors: Semenova Valeriia Valerevna , Zelenyuk Alexander Nikolaevich , Savinov Yuri Anatolyevich
Published: February 2021

The goal of the article is to analyze the development of the professional competency of leadership through the development of soft skills in the students of Russian engineering universities on the example of the Moscow Polytechnic University. The most demanded and dynamic part of the labor market is currently represented by engineering specialists. However, successful professional and career growth, as well as the effective development of human capital as the main resource of the innovative development of modern society, requires a combination of engineering (hard skills) and humanitarian (soft skills) abilities in a specialist. The development of many socially significant processes in modern society demonstrates aggravated contradictions and the development of new realization trends many of which are associated with changes in the parameters of these processes which, in turn, is determined by the mass implementation of innovative digital technologies and globalization processes. Globalization as a process ensuring the accessibility and openness of information has a significant impact on the transformation of national values within a country in favor of the emergence of global social, moral, and legal values and social behavior norms in the field of political and state power, as well as the economy. Leadership as a social phenomenon bearing the main load of managing all socially significant processes is also changing. Leadership as a social phenomenon is subject to constant scientific study and analysis. For this purpose, the GLOBE (Global Leadership and Organization Behavior Effectiveness) International Research Program was created. The GLOBE program coordinates the study of leadership in more than 60 countries which also supports the relevance of researching the phenomenon of leadership. In the professional activity, leadership manifests through the “leadership qualities” competency.
Modern communication technologies in education: book trailer
Authors: Nikonova Nadezhda Ilinichna , Zalutskaya Svetlana Yrievna
Published: February 2021

The article deals with the problem of encouraging the reading activity of pupils through modern communication technologies. As a tool to attract the attention of teenagers to reading, the authors turn to a multimedia advertising product, namely, a book trailer. The relevance of its application in teaching is determined by the context of the time, digitalization and virtualization of education, social trends, and features of the perception of information by today’s reader and viewer. The article substantiates the fruitfulness of using the book trailer in the educational environment by the results of content analysis of scientific works of Russian and foreign researchers, practitioners, and practical testing in the educational process. As an experimental research method, the authors used a survey of pupils of the sixth and seventh grades of the Second Malzhagar Middle School named after M.E. Vasilyeva of the “Khangalassky Ulus” municipal district, as well as rural teachers of the literature of the Republic of Sakha (Yakutia) of the Far Eastern Region of the Russian Federation. The survey involved 47 pupils and 31 respondents from among regional teachers of the Russian language and literature. The problem of reading was considered in terms of uncovering the creative potential of pupils of the sixth and seventh grades who were studying under the elective program "Book Trailer: Create, Watch, and Read". The research results aimed at determining the book trailer as an effective means of developing pupils’ interest in reading, implementing their creative abilities in the course of developing a product for the information and educational environment of the region. The authors conclude that the creation of book trailers is one of the most relevant motivators for pupils in their cognitive activity as it combines work with a book and mastering modern communication technologies, increases interest in learning and the level of motivation to read.
Evaluation of cultural sphere development in the European Union countries as a factor of forming social capital and creative industries: experience for Ukraine
Authors:   Ivan Franko National University of Lviv, Kichurchak Marianna
Published: February 2021

Taking into account the European integration course of Ukraine, it is necessary to evaluate the socio-economic conditions of cultural sphere development in the countries of the European Union, because it is an integral part of creative industries and improvement of social capital. The purpose of this research is to identify the factors of cultural sphere development in the EU countries due to its importance for the system of creative industries and the process of social capital accumulation, outlining the possibilities of European experience adaptation in this sphere for Ukraine. The scientific and methodology approaches were developed to the definition of cultural sphere development factors in the EU countries from the point of view of its influence on the formation of social capital and creative industries. A comparative analysis of socio-economic development of cultural sphere in 2011-2019 was realized, including evaluation of spatial differences in its functioning on the base of variation indicators calculating and tracking their dynamics. The specification of multiple regression models was done, in which the explained variables became employment in cultural sphere (Y1) and the value of its gross value added (Y2). It is found out that the place and significance of the cultural sphere for the national economy of each EU country differ, whereas the environment of its functioning is relatively stable, which contributes to the formation of proper conditions for the accumulation of social capital and the development of creative industries. It is substantiated that spatial differences in cultural sphere development have been intensified in the EU countries due to the different intensity of social capital and creative industries network formation. The multiple regression analysis revealed that a number of explanatory variables (demographic situation, tourism activity, unemployment rate, and education index) influence employment and gross value added of the cultural sphere. It is determined that for the cultural sphere of Ukraine, taking into account the European integration and experience of the EU countries, it is important to ensure the stability of cultural sphere, minimize the effects of the demographic crisis, promote tourism development, and regulate the employment policy, which, due to synergy, will influence the social capital and the positions of creative industries in the national economy.
Audit and accounting considerations on cryptoassets and related transactions
Authors:   Kyiv National Economic University named after Vadym Hetman, Ozeran Alla , Gura Nadiia ,   Taras Shevchenko National University of Kyiv
Published: February 2021

Introduction. The rapid rise and volatility of cryptoassets have led to increased global interest by governments, investors, regulators. In 2020, the market capitalization of cryptocurrencies increased to USD 758.06 billion by expert estimations. Each of the cryptoassets has its own unique features and characteristics which makes their accounting and auditing challenging. The lack of official accounting and auditing guidance for cryptoassets and related transactions impose additional audit risks that should be measured properly before the client-acceptance stage and planning audit procedures. We developed a model which links financial statement assertions, identified cryptoassets’ risks that should be considered during the audit, and related controls in response to such risks. The purpose of this paper is to identify cryptoassets framework for audit planning and gathering audit evidence to support management assertions regarding their financial statements. Methods. This paper adopts an empirical research approach with application of auditing and analytical procedures. In a comprehensive analytical overview of trends in cryptoassets market capitalization, the authors have used statistical methods and structural analysis, the selected sample includes daily data of cryptoassets market capitalization during January 2016 - February 2020. Results. According to the conducted research, the auditors have to consider whether to accept or continue an audit engagement when an entity has engaged in material cryptocurrency transactions; the auditors have to identify and assess risks of material misstatement in financial statements related to cryptoassets transactions and balances. We suggested a possible substantive audit procedures for cryptoassets and related transactions, such as: inspection of the wallets and verification the balances on them; confirmation by a third party (traders); inspection of documents supporting ownership of the asset (white papers, agreements with crypto-traders); testing client internal controls system and controls that are implemented to ensure the security of the private key of crypto-wallet. Conclusions. It is becoming common for financial statements to show cryptoassets balances and reflect the results of cryptoassets transactions, however, many auditors may have little or no experience with cryptoassets and therefore may not fully appreciate the challenges that auditing these items may present. The auditors need to identify and assess risks of material misstatement throughout the process of obtaining an understanding of the entity and its control environment, and evaluate the potential effect of that risks on financial statements.
Systematic expression and bioinformatics analysis of fibrinogen-like protein 1 in human cancer and its co-expression network
Authors: Wang Qian , Chen Shu-zhen , Zhang Hua-wei
Published: February 2021

Background

Fibrinogen-like protein 1 was initially found in a study on hepatocellular carcinoma and it is overexpressed in human cell lines and rats. Recently, investigations have focused on fibrinogen-like protein 1 dysfunction in carcinogenesis. Our study aims to determine the role of fibrinogen-like protein 1 and its possible role in human carcinoma.
Methods

Fibrinogen-like protein 1 expression in different neoplasms was assessed by Oncomine. Fibrinogen-like protein 1 coexpression networks in various cancers were established using Coexpedia. Finally, we investigated the potential functions of fibrinogen-like protein 1 with gene ontology and pathway enrichment analyses with the FunRich V3.
Results

Fibrinogen-like protein 1 was overexpressed in several kinds of neoplasms at the transcriptional level. Coexpression networks showed that fibrinogen-like protein 1 regulates immune response and lipid related pathways.
Conclusions

The present results offer the possibility that fibrinogen-like protein 1 acts as a therapeutic target for some types of cancers and may take part in carcinogenesis.
Finite Element Simulations for Entropy Generation Measurement in Single Phase Flow of Water Based Nanofluid Filled in Square Cavity under Appliance of Inclined Magnetic field
Authors: Bilal S.
Published: February 2021

Current communication candidly explicates entropy generation process generated due to natural convective heating in square enclosure saturated with nanofluid. Water is used as base fluid and Cu particles are induced to depict enhancement in thermo physical characteristics. Natural convection in enclosure is produced by providing temperature difference on boundaries. Upper wall is provided uniform temperature while rest of walls are kept cold. Impermeability and non-slip conditions are imposed on all walls. Mathematical structuring of considered problem is manifested via continuity, momentum and energy equations under appliance of inclined magnetic field. Thermo physical properties of nanoparticles along with base liquids are used during mathematical structuring. Finite element procedure is adopted to elucidate flow features. Discretization of domain is done by applying hybrid meshing. Velocity and isothermal plots are drawn against concerning parameters. Comprehensive description of energy generation by measuring variation in magnetic, viscous, total and thermal irreversibility’s are also presented. Cut lines representing velocity field in horizontal and vertical direction are also drawn to predict flow behavior at different locations.
Characteristics of Brain Structure in HIV Male Patients with Syphilis Co-Infection: A Cross-Sectional Study.
Authors: Qi Yu , Wang Yuan-Yuan , Wang Wei , Liu Xu-Ze , Liu Jing , Guo Yi-Fan , Ma Pei-Hong , Li Xing , Zhang Xiao-Dong , Yu Wen , Liu Jiao-Jiao , Liu Ming-Ming , Li Rui-Li , Li Hong-Jun
Published: February 2021

Background To investigate the effect of syphilis infection on the microstructure of white matter (WM) in HIV-infected male patients through comparing the differences of WM between HIV-infected male patients with and without syphilitic infection using diffusion tensor imaging (DTI).Methods 27 HIV-infected male patients with current syphilis or a history of syphilis (HIV+/syphilis+) and 29 HIV-infected male patients without syphilis co-infection history (HIV+/syphilis-) were enrolled. All patients received DTI and comprehensive neuropsychological assessment. Clinical data were compared between the two groups with T-test, Mann-Whitney U Test and Chi-square Test. Tract-based spatial statistics (TBSS) was adopted to analyze the DTI metrics. Multiple linear regression analysis was conducted to investigate the relationships between DTI metrics and clinical variables and cognitive performance. Results In the HIV+/syphilis+ group, decreased AD was found in the right superior corona radiata (SCR-R) and body of corpus callosum (BCC); increased RD was found in the bilateral posterior corona radiata (PCR), the right posterior thalamic radiation (PTR-R), the left SCR (SCR-L), splenium of corpus callosum (SCC) and BCC; decreased FA was found in multiple regions. AD in BCC was negatively correlated with CD4/CD8 ratios. AD in SCR-R was positively correlated with CD4/CD8 ratios. Patients in HIV+/syphilis+ group had a lower score in complex motor skills (CMS). RD in SCC and SCR-L was negatively correlated with CMS; RD in PTR-R was positively correlated with CMS. AD in SCR-R was positively correlated with CMS. Conclusions Compared with patients simply infected with HIV, the integrity of WM is more seriously impaired in HIV-infected patients with syphilis co-infection, and it may accelerate the impairment of cognitive function.
Symptomatic Lumbar Intradural Spinal Lipoma– Case Report
Authors: Davarski Atanas , Apostolov Georgi
Published: February 2021

Background

Intradural lipomas (IL) not associated with spina bifida in the lumbar region are rare and isolated cases have been reported in the literature. The current paper presents a case of a patient who suffers from intradural lipoma without spinal dysraphism in the lumbar region. We also made a brief literature review.
Case presentation:

A 31-year-old patient suffered from back pain resistant to medication for more than a year. Few weeks prior to hospitalization, the pain irradiated to the feet associated with numbness, weakness and urinary dysfunction. Upon hospitalization, partial cauda equina syndrome was diagnosed that included radiculopathy along L4-S1 nerve roots, predominantly on the left side, decreased tendon reflexes, left-sided fibular and tibial paresis. Partial urinary retention was also present. Magnetic resonance tomography demonstrated a lesion located in the dorsal intradural space at the level of L3–L4 vertebra that had fat-equivalent ovoid form compressing and dislocating the components of the dural sac ventrally. Laminectomy of L3 and L4 vertebrae was performed. We encountered an intradural tumor formation with a yellowish colour and that was adherent to the nerve roots of cauda equina. After microsurgical dissection of the nerve roots, the tumor was partially resected. The histological examination confirmed the diagnosis of lipoma. Postoperatively, the neurological status improved significantly. The pain syndrome, motor symptoms and pelvic reservoir dysfunction were reduced.
Conclusions

In cases with intradural lipomas, the earliest possible surgical decompression with maximal safe resection of the lesion is a therapeutic method of choice that results in significant improvement or complete recovery of the neurological deficit.