bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamics of solition of circular Pearcey Gaussian vortex beams in strongly nonlocal nonlinear media
Authors: Chen Chidao , Wu Jianwen , Deng Dongmei , Zhang Liping
Published: September 2023

The evolution of circular Pearcey Gaussian vortex beams (CPGVBs) in strongly nonlocal nonlinear media is investigated numerically. The breathers-like balance states of CPGVBs are obtained directly by adjusting the light field structure parameters of CPGVBs and the nonlinear factor. In particular, as the nonlinear factor increases, the number of CPGVBs foci increases and the distance between the foci decreases. Additionally, varying the parameters of the light field structure can modify the shape of the focal point and the distribution of the beam during propagation. Interestingly, by adjusting the nonlinear factor and the beam width of CPGVBs, the spatial optical soliton states in strongly nonlocal nonlinear media are obtained. In addition, the light field structure parameters of the CPGVBs have a significant impact on the shape of the spatial optical solitons during transmission.
Associations between Dietary behaviours and Mental and Physical Health among Swedish Adolescents: The Role of Socioeconomic and Demographic Status
Authors: Jonsson Kenisha Russell , Bailey Cameron K , Corell Maria , Löfstedt Petra , Adjei Nicholas Kofi
Published: September 2023

Aims
Our objective was to assess the association between dietary behaviours and the physical and mental health of Swedish adolescents, taking into account their socioeconomic and demographic characteristics.
Methods
We used data from the 2017/2018 Health Behaviour in School-aged Children (HBSC) survey, a comprehensive study comprising 3,692 adolescents aged 11-, 13- and 15- years old. The prevalence and association of dietary behaviours with socioeconomic and demographic factors was estimated. We further assessed the correlation between dietary habits, overweight/obesity and mental health using multivariate logistic regression, with and without model adjustment.
Results
Boys predominantly consumed breakfast and family meals but had lower fruit and vegetable intake, compared to girls. Adolescents from families with lower Family Affluence Scale (FAS) scores and perceived family wealth had poorer dietary habits. Regular breakfast, family meals, consistent fruit and vegetable consumption were positively associated with mental health. Daily family meals in particular were correlated with heightened life satisfaction (OR:1.55, CI: 1.27–1.88), fewer psychosomatic complaints (OR: 0.78, CI: 0.69–0.89), and diminished school stress (OR:0.67, CI: 0.58–0.77). Breakfast was found to be a beneficial dietary habit, while frequent sugar-sweetened beverage consumption negatively impacted life satisfaction. Daily breakfast was associated with lower odds of overweight or obesity, but other dietary behaviours showed no significant relationship with weight status.
Conclusions
Dietary habits are intricately linked to the mental and physical health of adolescents. Socioeconomic and demographic factors play a pivotal role in influencing these behaviours. Recognizing the health disparities based on these factors is vital for developing effective, tailored interventions, especially for the low-income and vulnerable groups.
Hydrogen sulfide priming enhanced salinity tolerance in sunflower by modulating ion hemostasis, cellular redox balance, and gene expression
Authors: Younis Abeer Abdelrazk , Mansour Mohamed Magdy F.
Published: September 2023

Background
The salinity threat represents one of the environmental challenges that drastically affect plant growth and yield. Besides salinity stress, the escalating world population will greatly influence the world’s food security in the future. Therefore, searching for effective strategies to improve crop salinity resilience and sustain agricultural productivity under high salinity is a must. Seed priming is a reliable, simple, low-risk, and low-cost technique. Therefore, this work aimed to evaluate the impact of seed priming with 0.5 mM NaHS, as a donor of H2S, in mitigating salinity effects on sunflower seedlings. Primed and nonprime seeds were established in nonsaline soil irrigated with tape water for 14 d, and then exposed to 150 mM NaCl for 7 d.
Results
Salinity stress significantly reduced the seedling growth, biomass accumulation, K+, Ca2+, and salinity tolerance index while elevating Na+ uptake and translocation. Salinity-induced adverse effects were significantly alleviated by H2S priming. Upregulation in gene expression (HaSOS2, HaGST) under NaCl stress was further enhanced by H2S priming. Also, H2S reduced lipid peroxidation, electrolyte leakage, and H2O2 content, but elevated the antioxidant defense system. NaCl-induced levels of ascorbate, glutathione, and α tocopherol, as well as the activities of AsA-GSH cycle enzymes: ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase, glutathione reductase, and glutathione S-transferase, were further enhanced by H2S priming. Increased level of H2S and total thiol by NaCl was also further stimulated by H2S priming.
Conclusion
H2S priming has proved to be an efficient strategy to improve sunflower seedlings’ salinity tolerance by retaining ion homeostasis, detoxifying oxidative damage, modulating gene expression involved in ion homeostasis and ROS scavenging, and boosting endogenous H2S. These findings suggested that H2S acts as a regulatory molecule activating the functional processes responsible for sunflower adaptive mechanisms and could be adopted as a crucial crop management strategy to combat saline conditions.
Two-way predation between larvae of Spodoptera frugiperda and Spodoptera litura
Authors: Wang Yuxue , Mbiza Natasha Isabel Tanatsiwa , Zhang Haoran , Hu Zongwei , Liu Ting , Wang Yi , Zhang Yi , Luo Xincheng , Chu Longyan , Yang Yazhen , Wang Xiangping , Li Chuanren , Zhang Jianmin , Yu Yonghao
Published: September 2023

Spodoptera frugiperda has co-occurred with the Spodoptera litura in corn fields since it invaded China on December, 2018. In our process of rearing S. frugiperda and S. litura larvae in the lab, we discovered that when the larvae of S. litura and S. frugiperda were on the same host plant, the two-way predation between them occurred. However, a detailed study on this phenomenon has not been reported currently. Therefore, the study on the two-way predation between larvae of S. frugiperda and S. litura was performed under mimicing natural conditions including the presence or absence of maize leaves. The results showed that 4th instar larvae of S. frugiperda could prey actively on the 3rd instar larvae of S. litura under natural conditions in the greenhouse, and there was two-way predation between S. frugiperda and S. litura larvae in either the presence or absence of maize leaves in the lab. In addition, the difference in the daily predation number of S. frugiperda larvae (4th-6th instar) on young larvae of S. litura(1st-3rd instar) was significant between presence and absence of maize leaves. Similarly, the difference in the daily predation number of S. litura larvae (4th-6th instar) on S. frugiperda younglarvae (1st-3rd instar) was very significant between presence and absence of maize leaves. These results confirm that two-way predation exists between larvae of S. frugiperda and S. litura and provide a new strategy for the green control for S. frugiperda.
TGF β1 negatively impacts liver regeneration under chemotherapy
Authors: Račkauskas Rokas , Lukšaitė-Lukštė Raminta , Stulpinas Rokas , Paškonis Marius , Sokolovas Vitalijus , Laurinavičius Arvydas , Strupas Kęstutis
Published: September 2023

Background: In the modern surgical and chemotherapy era metastatic liver disease is in the renaissance, enabling to extend patient's life with metastatic liver disease. However, the primary limiting factor to more radical surgical treatment is liver volume, particularly in patients with chemotherapy-induced liver damage. Since results regarding whether chemotherapy has an impact on liver volume regeneration are ambiguous, we have aimed to analyze liver regeneration and the factors influencing it.
Methods: A prospective cohort study was performed. Patient inclusion criteria were as follows: patients between 18 and 90 years; liver resection of at least 2 segments either for benign or colorectal cancer metastasis; patients who underwent liver resection due to metastatic disease had to have previous chemotherapy treatment. All patients were divided into 2 groups – control and chemotherapy groups. Analysis of demographics, perioperative data, liver enzymes, liver stiffness, and liver volume was carried out, as well as the impact on regeneration marker expression in serum and liver tissue.
Results: 34 patients in all were involved in this trial, and they were split into two groups: chemotherapy and control. The two groups were similar. Except for comorbidities, there were no variations between the perioperative and demographic data. In the chemotherapy group, regenerated liver volume was lower compared to control, 1240.5±69.6 vs 1525.3±106.6 ml p-0.039. Further analysis revealed that the chemotherapy group had increased anti-regenerative TGF β1 expression compared to control in serum and liver tissue, p-0.02 and p-0.034.
Conclusions: The present study showed that chemotherapy is associated with lower regenerated volume in patients who received resection. Anti-regenerative TGFβ1 marker expression in liver tissue and serum might have an impact on regenerated liver volume, however, the exact mechanisms involved in decreased regeneration are further to be studied.
Seasonal Variation of Body Condition in Feral Horses at Tornquist Park, Southern Pampas, Argentina
Authors: Franco Bostal , Luis Scorolli Alberto , Martín Zalba Sergio
Published: September 2023

Body condition of feral horses is important for animal welfare considerations and to anticipate population densities that may cause negative effects on the ecosystem. Body condition scores (BCS) of adult males and females were monthly estimated in 2001 and 2002 for a dense population of feral horses in a grassland nature reserve in Argentina. Monthly mean BCS showed a seasonal pattern for both sexes. Female BCS was higher throughout 2001 with respect to 2002, while males only showed this pattern between wet seasons. BCS was higher for males than for females throughout the study, and also higher during the wet season for both sexes. Mean monthly BCS of males was correlated to precipitation of the previous month. The seasonal variation found tracks the known trend in grass productivity in the area. Lower BCS values for females can be explained by the additional energy expenditure associated with pregnancy and lactation. The appropriate time to monitor body condition in the area would be during the autumn rainfall peak or the winter minimum, and the estimates corresponding to females more precise considering their dependence to density and rainfall. The implementation of management measures guided by BCS could minimize the risk of reaching population levels close to carrying capacity, reducing the negative impacts on the environment and on the welfare of the horses themselves.
IoT-AgriSens: A LoRa-Based Smart Agriculture Monitoring and Decision-Making System with Amalgamation of IoT and Cloud- Enabled Services
Authors: K Lova Raju , V Vijayaraghavan
Published: September 2023

Acquiring real-time agricultural data for field monitoring and crop yield predictions is difficult. Real-time sensors enable field monitoring and agricultural yield modeling. Existing systems for real-time data modeling and field monitoring are inadequate. The majority of smart agricultural systems only measure air temperature and humidity and these systems are unable to send sensor data long distances. In addition to a data transmission range of 100 meters, these devices have limitations for agricultural field coverage. Therefore, crop yields are under expectations. The problems are addressed through an architectural framework. An agri-field architecture that monitors air temperature and humidity, soil temperature, soil moisture, and soil pH in real time is presented. The design uses open-source platforms and features a transmitter and receiver. The WSAMU (Wireless Smart Agriculture Monitoring Unit) analyzes and sends environmental and field data to a LoRa gateway. A LoRa gateway allows a WSAMU to send data to a WARMU (Wireless Agriculture Receiver Monitoring Unit). The following key experiments validated the proposed architecture: (a) Five sensors with WSAMU attached to LoRa, HC-12, and Wi-Fi networks. In agriculture, sensors are deployed. (b) An experimental setup was arranged to measure the current supply in operational and non-operational approaches of 0.8840 A*s and 1.0424 A*s respectively. The contributions of a WSAMU to calculate its typical current use. (c) The life expectancy of a WSAMU was estimated as approximately 4 days under hypothetical conditions. To support smart agriculture monitoring and decision-making, the Measurement Index (MI) has been developed based on all sensor data.
Malignant glaucoma presenting with deep central anterior chamber after laser-assisted cataract surgery: A case report
Authors: Hu Jun , Zhang Wanping , Zhou zheng , Lei Qiong
Published: September 2023

Background
Malignant glaucoma is characterized by a shallow of the central and peripheral anterior chambers of the eye, often elevated intraocular pressure, and in a small number of patients, early intraocular pressure may be normal. we describe a patient who developed malignant glaucoma presenting with deep central anterior chamber after laser-assisted cataract surgery. After anterior vitrectomy, the patient's symptoms were controlled.
Case presentation:
A 59-year-old female patient who was diagnosed as binocular age-related cataract, binocular primary angle-closure glaucoma (advanced in left eye, early in right eye), binocular medullated nerve fiber underwent femtosecond laser-assisted cataract phacoemulsification plus intraocular lens implantation plus goniosynechialysis in our hospital. The operation was successfully completed without special conditions. After surgery, both eyes showed increased intraocular pressure, normal central anterior chamber depth, and varying degrees of myopic drift. Based on the patient's condition and related examinations, the final diagnosis was binocular malignant glaucoma, and the anterior vitrectomy of both eyes was performed successively. After surgery, the intraocular pressure of both eyes returned to normal.
Conclusions
From this case, what we could learn is that the typical symptoms of malignant glaucoma are missing sometimes, which make diagnosis more difficult and often delayed treatment of patients. Therefore, we should remain highly suspicious of any disease and do not miss a diagnosis in clinical practice.
Nanotheranostic Trojan Horse for Visualization and Photo-Immunotherapy of Multidrug-Resistant Bacterial Infection
Authors: Pang Xin , Xu Haohang , Geng Qishun , Liu Heng , Zhang Xiao , Miao Mingsan
Published: September 2023

Effective diagnosis and therapy for bacterial infections, especially those caused by multidrug-resistant (MDR) species, greatly challenge current antimicrobial stewardship. Monocytes, which can chemotactically migrate from the blood to infection site and elicit a robust infection infiltration, provides a golden opportunity for bacterial theranostics. Here, an endogenous cell hitchhiking nano-Trojan Horse was facilely engineered using mannose-functionalized manganese-eumelanin coordination nanoparticles (denoted as MP-MENP) for precise two-step localization and potent photothermal-immunotherapy of complicated MDR bacterial infection. Taking advantage of the selective recognition between mannose and inflammation-associated monocytes, the MP-MENP could be passively piggybacked to infection site by circulating monocytes, and also actively target infiltrated monocytes that are already accumulated in infection microenvironment. Such dual-pronged targeting enabled an efficient photoacoustic and magnetic resonance imaging of bacterial infection. Upon laser irradiation, the MP-MENP robustly produced local hyperemia to ablate pathogenic bacteria, both extracellularly and intracellularly. Further combined with the synergistic effect of immunogenic cell death induced by photothermal therapy and macrophage reprogramming by MP-MENP, the immunosuppressive infection microenvironment was significantly relieved, allowing an enhanced antibacterial immunity. Collectively, the proposed nanotheranostic Trojan Horse, which integrate dual-pronged targeting, precise imaging diagnosis, and high-performance photothermal immunotherapy, promise a new way for complete eradication of MDR bacterial infection.
Improving the Application Performance of Loki via Algorithm Optimization
Authors: Zhu Wenming , Su Wenjing , Yang Kai , Chen Hao
Published: September 2023

Loki is a state-of-the-art adaptive bitrate algorithm for the transmission of real-time-communication (RTC) video. It fuses traditional heuristic methods with a learning-based model to maximize the quality of experience (QoE) under diverse network conditions. However, a recurring rebound pattern is observed in Loki’s decision-making process where the decision frequently oscillates between the two boundaries of the action space, making Loki fail to adapt to the fluctuating network bandwidth. To address this issue, we propose Loki+, which improves both the fusion mechanism and the design of the learning-based actor. Specifically, we replace the element-wise multiplication with a simple but effective trend fusion and further optimize the design of reward and loss functions for training Loki+. Extensive simulation results show that Loki+ significantly improves the QoE in the aspects of reducing the stall rate by 20%∼60% and the frame delay by 3.5%∼30.5% while maintaining a similar sending bitrate or video quality, compared with Loki.
The impact of blood MCP-1 levels on Alzheimer’s disease with genetic variation of UNC5C and NAV3 loci
Authors: Huang Jinghan , Wang Yixuan , Stein Thor D. , Ang Ting Fang Alvin , Zhu Yibo , Tao Qiushan , Lunetta Kathryn L. , Mez Jesse , Au Rhoda , Farrer Lindsay A. , Qiu Wei Qiao , Zhang Xiaoling
Published: September 2023

Background
Previous study shows that monocyte chemoattractant protein-1 (MCP-1), which is implicated in the peripheral proinflammatory cascade and blood-brain barrier (BBB) disruption, modulates the genetic risks of AD in established AD loci.
Methods
In this study, we hypothesized that blood MCP-1 impacts the AD risk of genetic variants beyond known AD loci. We thus performed a genome-wide association study (GWAS) using the logistic regression via generalized estimating equations (GEE) and the Cox proportional-hazards models to examine the interactive effects between single nucleotide polymorphisms (SNPs) and blood MCP-1 level on AD in three cohorts: the Framingham Heart Study (FHS), Alzheimer’s Disease Neuroimaging Initiative (ADNI) and Religious Orders Study/Memory and Aging Project (ROSMAP).
Results
We identified SNPs in two genes, neuron navigator 3 (NAV3, also named Unc-53 Homolog 3, rs696468) (p < 7.55×10− 9) and Unc-5 Netrin Receptor C (UNC5C rs72659964) (p < 1.07×10− 8) that showed an association between increasing levels of blood MCP-1 and AD. Elevating blood MCP-1 concentrations increased AD risk and AD pathology in genotypes of NAV3 (rs696468-CC) and UNC5C (rs72659964-AT + TT), but did not influence the other counterpart genotypes of these variants.
Conclusions
NAV3 and UNC5C are homologs and may increase AD risk through dysregulating the functions of neurite outgrowth and guidance. Overall, the association of risk alleles of NAV3 and UNC5C with AD is enhanced by peripheral MCP-1 level, suggesting that lowering the level of blood MCP-1 may reduce the risk of developing AD for people with these genotypes.
SEREIA - Document Store Exploration through Keywords
Authors: Afonso Ariel Antony Afonso , Martins Paulo Rodrigo Oliveira Martins , Soares Altigran Soares da Silva
Published: September 2023

The adoption of document stores, such as MongoDB or CouchDB, has drastically increasedin the past years. Part of this popularity can certainly be explained by their flexibility interms of loading, storing, and retrieving semi-structured data on massive scales. However,adopting such systems presents challenges when exploring the data they store since thestructure of the document may not follow a single pattern, and thus present complexhierarchical and nested structures that vary. Additionally, an analyst who wants to retrievedata may experience difficulties since she must learn the specificities of the document store’snative query language. In this work, we propose SEREIA, a system that facilitates dataexploration in document stores through keyword search. The user inputs a non-structuredkeyword-based query and the system generates a structured query for the document storethat fulfills her information needs. We evaluated SEREIA using five datasets previously usedin the literature and the results we achieved indicate that SEREIA is suitable for helping usersin data exploration tasks by removing the burden of understanding the data organization ofthe stored documents and by automatically generating queries to explore data of interest.
Multiple Thrombi mimicking metastases in the right atrium of patients with non-Hodgkin's lymphoma diagnosed by multimodal cardiac imaging：one case report
Authors: Hu Zhiqiang , Yuan Shuai , Mou Yun
Published: September 2023

Background：
Right-side heart mass can be found incidentally on routine transthoracic echocardiography (TTE). Accurate diagnosis of cardiac mass often requires more than one imaging method. We present a mid-age woman with non-Hodgkin lymphoma who was found to have multiple right atrial masses mimicking metastases on routine TTE, which were diagnosed as thrombi by multimodal cardiac imaging eventually. The masses were removed by cardiopulmonary bypass thoracotomy because of a high risk of pulmonary embolism.
Case presentation:
A 52-year-old woman was diagnosed with primary mediastinal diffuse large B cell lymphoma (DLBCL) almost six months prior. The TTE revealed multiple masses in the right atrium with normal cardiac function when she was being evaluated for the next chemotherapy. On arrival, she was hemodynamically stable and asymptomatic. Physical examination was no remarkable. Laboratory findings showed leukocytosis of 17,900 cells/mm3, hemoglobin of 7.5 mg/dL, and a normal D-dimer level. The suspicious diagnosis of right atrial metastasis was made by TEE. However, the diagnosis of right atrial thrombi was made by contrast CMR. Finally, the 18F-FDG PET-CT demonstrated no metabolic activity in the right atrium, which further established the diagnosis of thrombi. Eventually, the masses were removed by cardiopulmonary bypass thoracotomy because of a high risk of pulmonary embolism, and confirmed thrombi by histopathology.
Conclusions:
This case highlights the importance of multimodality cardiac imaging in the appropriate diagnosis of a RA masses in patient of lymphoma. Diagnosis of RA masses can be made using multimodal cardiac imaging like TTE, TEE and CMR, even PET. Echocardiography is the most commonly used on multimodal imaging in cardiac thrombus. CMR has high specificity in differentiating a tumor from thrombus, and 18F-FDG PET has more sensitivity to determine the nature of the masses.
The Dynamic Impact and Spatial Spillover of Digital Economy on the High-quality Development of China's Manufacturing Industry from a Sustainable Perspective
Authors: Ren Fang-rong , Liu Xiao-yan , Ji Mi , Ren Yang-jun
Published: September 2023

Based on panel data from 30 provinces in mainland China from 2011 to 2017, this research investigates the spatial spillover effect and nonlinear impact of digital economy (DE) on green and high-quality manufacturing industry (GHMI) using the spatial econometric and panel threshold model. It is found that both the DE and GHMI have a significant positive spatial correlation. The spatial econometric model under different weights all illustrate that regional DE has not significantly promoted GHMI in local region, but produced a significant positive influence on GHMI in neighboring regions. The east region has a higher degree of DE, while the level of DE in the central and west regions are both lower and close to each other. The level of GHMI shows a decreasing pattern in the east, central and west regions in that order. In addition, the impact of DE on GHMI presents a significant single threshold effect. With the improvement of DE, GHMI has a U-shaped change trend. Attention should be paid to the threshold effect of DE on GHMI, control the development speed of DE within a reasonable range, scientifically allocate DE resources according to different regional economic development levels in order to promote GHMI.
Wish You Were Here? the Economic Impact of the Tourism Shutdown from Australia’s 2019-20 ‘Black Summer’ Bushfires
Authors: Reiner Vivienne , Pathirana Navoda Liyana , Sun Ya-Yen , Lenzen Manfred , Malik Arunima
Published: September 2023

Tourism, including education-related travel, is one of Australia’s top exports and generates substantial economic stimulus from Australians travelling in their own country, attracting visitors to diverse areas including World Heritage rainforests, picturesque beachside villages, winery townships and endemic wildlife. The globally unprecedented 2019-20 bushfires burned worst in some of these pristine tourist areas. The fires resulted in tourism shutting down in many parts of the country over the peak tourist season leading up to Christmas and into the New Year, and tourism dropped in many areas not physically affected by the fires. Our research quantified the cost of the short-term shock from tourism losses across the entire supply chain using input-output (IO) analysis, which is the most common method for disaster analysis; to this end, we also developed a framework for disaggregating the direct fire damages in different tourism sectors from which to quantify the impacts, because after the fires, the economy was affected by COVID-19. We calculated losses of AU$2.8 billion in total output, $1.56 billion in final demand, $810 million in income and 7300 jobs. Our estimates suggest aviation shouldered the most losses in both consumption and wages/salaries, but that accommodation suffered the most employment losses. The comprehensive analysis highlighted impacts throughout the nation, which could be used for budgeting and rebuilding in community-and-industry hotspots that may be far from the burn scar.

CLASSIFICATION CODES
MSC:
15B99 (Linear and multilinear algebra; matrix theory)
JEL
C67 (Input-Output Models)
Z3 (Tourism Economics)
A Novel Innovative Approach for Text Document Identification through Word Clouds technique
Authors: Khandagale Sachin , Kurundkar Gajanan , Tathe Rajkumar , Kawade Dipak
Published: September 2023

Text is a versatile and valuable approach to conveying information and knowledge. Unstructured data, however, poses challenges when it comes to reading and extracting valuable information. Users cannot find their subject domains within a matter of seconds without reading them at all. To accurately determine the category of a document or text data, the user must identify the presence of certain key sections in the document. So, text analysis is required to get hidden features from data. Word cloud is one of the important tools in machine learning useful for summarizing and visualizing important words and themes. It can extract relevant features necessary for categorizing text documents into appropriate themes. In this study, we use a document identification approach based on word clouds. The present study uses various news for identification purposes which were downloaded from different newspaper websites. People can find their topics in seconds without even reading them. This study provides numerous interactive graphics and robust, customizable features to help understand the subject of a document.
The Second Time to Measure the Gravitational Constant G Between Massive Objects
Authors: HU qinggui , Xinlong ZHANG
Published: September 2023

Cavendish torsion experiment is the most important experiment to measure the gravitation constant G all over the world. However, it can only measure the gravitational constant between small objects. In 2008, the new experiment was put forward. It can measure G between huge objects. At the same time, the new theory was put forward also: The universal gravitation would be the resultant of the attraction and repulsion forces of the countless molecules and atoms between the two objects, it is possible for the gravitation constant G to have a variable value. The paper was published on the Journal of Hebei University of Science and Technology, Volume 29, Issue 2. In 2021, the experiment was carried out and new G between 2 kg iron ball and 20 t steel plate was obtained, which was 9.09× 10-9 N · m 2 /kg 2. While the internationally recognized value is 6.672 59 ×10-11 N · m 2 /kg 2 , there is a significant difference between the two values, which is difficult to explain with traditional theories. Therefore, in early June 2023, we established another experimental platform to do the experiment again. The new G between 5 kg iron ball and 30 t steel plate was obtained, at this time, it was 1.407991 × 10-9 N · m 2 /kg 2. The accuracy of this experiment is 97.4%. The new experimental results provide another perspective for studying the theory of gravity. We hope more colleagues to do the new experiment once more.
Plasma Cell-Free Adenomatous Polyposis Coli Gene Promoter Methylation as a Prognostic Biomarker for Hepatocellular Carcinoma
Authors: Hsiao Chih-Yang , Lu Chang-Yi , Su Hung-Ju , Huang Kai-Wen
Published: September 2023

Introduction: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide. Lack of biomarkers for early diagnosis and follow up after treatment is one of the clinical obstacles for effective treatment of HCC. DNA methylation has been proposed to be a potential biomarker in HCC. However, there is still lacking of evidence of its clinical use. The aim of this study is to evaluate the value of using plasma Adenomatous Polyposis Coli promoter methylation (APC-MET) as a potential biomarker in HCC treatment.
Method: A total of 96 patients with HCC at BCLC stage B underwent local tumor ablation treatment were prospectively included in this study. APC-MET was examined from the plasma of each patients before and 1 months after treatment. The prediction value of APC-MET for survival outcome and disease status after treatment were analyzed, and adjusted with alpha-fetoprotein and protein induced by vitamin K absence-II using cox regression analysis.
Results: Univariate cox regression analysis showed preoperative APC-MET >0 (HR, 2.9, 95% CI 1.05－8.05, p=0.041) and postoperative APC-MET >0 (HR, 3.47, 95% CI 1.16－10.4, p=0.026) were both predictors of death, and preoperative APC-MET >0 was a predictor of disease progression after treatment (HR, 2.04, 95% CI 1.21－3.44, p=0.007). In multivariate models, pre-op APC-MET >0 was a significant predictor of disease progression after adjusting with other two traditional biomarkers (HR, 1.82, 95% CI 1.05－3.17, p=0.034).
Conclusions: Hypermethylation of APC promoter appears to be a potential new biomarker that could predict patient survival and disease progression outcome in patients with intermediate stage HCC after local ablation treatment.
Determination of the Chemical and Proximate Properties of Fresh Milk Samples From Small Holder Dairy Cows and Large Mechanized Dairy Cows in Parts of Kaduna State, Nigeria.
Authors: Abubakar Umar
Published: September 2023

The Chemical and Proximate composition of different raw fresh milk samples from small holder dairy cows and large mechanized dairy cows in Zaria and Kaduna in Kaduna State, Nigeria were determined using standard methods and EDRXF spectrophotometer. The mean values of the pH based on farm locations ranged between 6.71 ± 0.03–6.81 ± 0.02 and the titratable acidity ranged from 0.15 ± 0.04–0.17 ± 0.03. From the various farms, while the mean values of the proximate composition of milk from the various farms ranged from 86.30 ± 0.01–87.94 ± 0.04 for moisture up to 12.51 ± 0.01–13.82 ± 0.01 for Total solids. Based on the different farm management locations, the proximate values for moisture ranged from 86.38 ± 0.01–87.25 ± 0.18 while that of Total solids ranged from 12.96 ± 0.12–13.49 ± 0.02. The statistical analysis of the obtained result at 0.05 probability value showed significant differences between pH values, between acidity values as well as in the values of the proximate characteristics from the different farm locations which were attributable to the differences in the farm management practices.
Sensitivity of Staphylococcus Species From Fresh Raw Milk Samples to Common Antibacterial Agents in Parts of Kaduna State, Nigeria
Authors: Abubakar Umar
Published: September 2023

The global problem of antimicrobial resistance is particularly pressing in developing countries of which Nigeria is not left out. The aim of the study is to test the susceptibility or resistance of Staphylococcus species from milk samples to commonly used antibiotics. A total of 592 quarter milk samples, 30 bulk milk samples and 27 swab samples of the hands of milk men were examined from 12 dairy farms in Kaduna and Zaria. One hundred and three (103) Staphylococcal isolates that were Gram positive and catalase positive were identified biochemically, out of which the identities of 51 different Staphylococcal species were confirmed using the Microbact Microgen kit. From these, 30 selected isolates were tested against 9 commonly used antibiotics. The antibacterial sensitivity pattern of the 30 isolates to common antibiotics showed a complete (100%) resistance to Amoxicillin and a complete (100%) susceptibility to Ciprofloxacin, but the isolates showed varying degrees of resistance & susceptibility to the other antibacterial agents. All the isolates exhibited multiple antibiotic resistance to 3–6 antibiotics. Methicillin resistance was manifested in the resistance of the organisms to Cefoxintin (a surrogate of Methicillin).
The Effect of the Internal Customer (Employee) on the External Customer in Citizenship Behavior: A Mediated Model Through Customer Support Perception
Authors: Kerse Yagmur , Kerse Gokhan
Published: September 2023

Organizational citizenship behaviour, which refers to employees exhibiting extra-role behaviours without expecting any tangible reward, can also be observed in customers. Similar to employees, customers can also engage in voluntary behaviours that are beneficial to the business (customer citizenship behaviour). These behaviours exhibited by both employees and customers areimportant for businesses to achieve their goals and survive. Therefore, the main purpose of this study is to determine the direct and indirect effects of employees’ citizenship behaviours on customers’ citizenship behaviours. The study formulated hypotheses based on social exchange theory, examining organizational citizenship behaviour’s direct effect on customer citizenship behaviour as well as its indirect effect on customer support perception. To test these hypotheses, data were collected from 302 customers of clothing stores in Turkey. The data were analysed using SPSS, AMOS, and Process MACRO (for SPSS and SAS) programs. The data were subjected to various procedures. Specifically, frequency analysis, normality test analysis, confirmatory factor analysis, and reliability analysis were conducted. In addition, detection analyses for method-related problems (multicollinearity and common method bias), correlation analysis, and regression analysis were performed. The results indicated that the data met the assumption of a normal distribution, the scales used were reliable and valid, and there was no evidence of multicollinearity or common method bias. Controlling for demographic variables, the correlation analysis revealed positive relationships between perception of organizational citizenship behaviour, customer citizenship behaviour and customer support perception. The regression analysis conducted to test the hypotheses revealed that organizational citizenship behaviour has a positive effect on customer citizenship behaviour. Moreover, the results indicated that customer support perception plays a mediating role in this effect. In other words, organizational citizenship behaviour affected customer citizenship behaviour both directly and indirectly (through customer support perception). These findings indicate that employees who are “good soldiers” influence customers to be “good soldiers” as well. Therefore, the study proved the importance of the internal customer (employees) for businesses in influencing the behaviour of external customers. Implications were made based on the findings in the study.
Social Media, Networks, and Students in the Context of the Educational Process
Authors: Chovanova Supekova Sona , Keklak Richard , Masarova Tatiana , Jakesova Patricia
Published: September 2023

Social media and networks have opened new opportunities for individuals to learn and grow, regardless of their educational or professional background. The implications and challenges of technology in educational settings are not well understood, despite its widespread use and impact on students. The study aims to investigate students’ social networking behaviour in the form of the use of social networking sites during class in relation to their gender, age group, education, and place of residence and focuses on three age groups of students who are representatives of Generation Y and Generation Z because both generations are growing up and coming of age in the 21st century and have been exposed to digitization and digital transformation since early childhood. The research sample consisted of 278 students from public and private universities and high school graduates who expressed interest in studying at the university. The results show that all examined variables, except place of residence, have a significant but small effect on what students do on social networking sites during classes and the reasons why they use them. However, according to the results, the fact that students connect to social networks during class does not imply that they have a reduced interest in the subject matter being taught or the knowledge being acquired, which means that there is a significant opportunity to adapt the learning approach on these platforms.
Proton penetration efficiency over a high altitude observatory in Mexico
Authors: Miyake S. , Koi T. , Muraki Yasushi , Matsubara Y. , Masuda S. , Miranda P. , Naito T. , Ortiz E. , Oshima A. , Sakai T. , Sako T. , Shibata S. , Takamaru H. , Tokumaru M. , Valdés-Galicia J. F.
Published: September 2023

In association with a large solar flare on November 7, 2004, the solar neutron detectors located at Mt. Chacaltaya (5,250 m) in Bolivia and Mt. Sierra Negra (4,600 m) in Mexico recorded very interesting events. In order to explain these events, we have performed a calculation solving the equation of motion of anti-protons inside the magnetosphere. Based on these results, the Mt. Chacaltaya event may be explained by the detection of solar neutrons, while the Mt. Sierra Negra event may be explained by the first detection of very high energy solar neutron decay protons (SNDPs) around 6 GeV.
Muon puzzle in inclined muon bundles detected by NEVOD-DECOR
Authors: Bogdanov Aleksei , Barbashina N. S. , Khokhlov S. S. , Kindin V. V. , Kokoulin R. P. , Kompaniets K. G. , Konovalova A. Y. , Mannocchi G. , Petrukhin A. A. , Shutenko V. V. , Trinchero G. , Vorobev V. S. , Yashin I. I. , Yurina E. A. , Zadeba E. A.
Published: September 2023

The data of cosmic ray NEVOD-DECOR experiment on the investigation of inclined muon bundles for a long time period (May 2012 - March 2021) are presented. The analysis showed that the observed intensity of muon bundles at primary cosmic ray energies of about 1 EeV and higher can be compatible with the expectation in frame of widely used hadron interaction models only under the assumption of an extremely heavy mass composition. This conclusion is consistent with data of several experiments on investigations of muon content in air showers, but contradicts the available fluorescence data on X_{max}Xmax which favor a light mass composition at these energies. In order to clarify the nature of the "muon puzzle", investigations of the muon bundle energy deposit in the detector material were carried out. For the first time, experimental estimates of the average energy of muons in the bundles of inclined air showers initiated by primary particles with energies from 10 to 1000 PeV have been obtained.
Overview of quarkonium production with ALICE at the LHC
Authors: Hushnud Hushnud
Published: September 2023

ALICE is a general purpose experiment designed to investigate nucleus-nucleus collisions at the Large Hadron Collider (LHC), located at CERN. The ALICE detector is optimized for the reconstruction of quarkonia through the dimuon decay channel at foward rapidity as well as the dielectron decay channel at midrapidity. In this contribution, quarkonium measurements performed by the ALICE collaboration at both midrapidity and forward rapidity for various energies and colliding systems (pp, p-Pb and Pb-Pb), will be discussed and compared to theory.
The ALPACA experiment: The project of the first sub-PeV gamma-ray observation in the southern sky
Authors: Kawashima Teruyoshi
Published: September 2023

The ALPACA experiment is a project aiming to observe sub-PeV gamma rays for the first time in the southern hemisphere. The main goal of ALPACA is to identify PeVatrons, the accelerators of Galactic PeV cosmic rays, by observing sub-PeV pion-decay gamma rays generated in interactions between PeV cosmic rays and the interstellar medium. This new air shower experiment is located at an altitude of 4,740 m above sea level in the middle of Mt. Chacaltaya in Bolivia. The air shower array consists of 401 scintillation counters covering an 83,000 m^22 surface area. In addition, a water-Cherenkov-type muon detector array with an area of 3,700 m^22 is installed to discriminate gamma rays from background cosmic rays. The prototype array ALPAQUITA will start data taking in 2022 and will extend to ALPACA in 2024. We report on a general introduction to ALPACA, the progress of the project, and the sensitivity to sub-PeV gamma rays.
Point sources of ultra-high-energy neutrinos: Minimalist predictions for near-future discovery
Authors: Fiorillo Damiano F. G. , Bustamante Mauricio , Valera Victor B.
Published: September 2023

The discovery of ultra-high-energy neutrinos, with energies above 100 PeV, may soon be within reach of upcoming neutrino telescopes. We present a robust framework to compute the statistical significance of point-source discovery via the detection of neutrino multiplets. We apply it to the radio array component of IceCube-Gen2. To identify a source with 3\sigma3σ significance, IceCube-Gen2 will need to detect a triplet, at best, and an octuplet, at worst, depending on whether the source is steady-state or transient, and on its position in the sky. The discovery, or absence, of sources significantly constrains the properties of the source population.
On irregularities in the cosmic ray spectrum of \(10^{16}-10^{18}\) eV range
Authors: Knurenko Stanislav P. , Petrov Igor S.
Published: September 2023

Existing small, medium and large arrays for the study of cosmic rays of ultra-high energies are aimed for obtaining information about our galaxy and extragalactic space, namely to search and study astronomical objects that produce the flux of relativistic particles. The drift and interaction of such particles with magnetic fields and shock waves taking place in interstellar space causes the same interest. The shape of the energy spectrum of cosmic rays in the energy range 10^{15}-10^{18}1015−1018 eV, where the "knee" and the "second knee’’ are observed, can be formed as a superposition of the partial spectra of various chemical elements. Verification of galactic models, using recent experimental spectral data, makes it possible to study the nature of the galactic and extragalactic components of cosmic rays. The paper presents the result of the energy spectrum of cosmic rays in the range 10^{16}-10^{18}1016−1018 eV of measurements obtained with the Small Cherenkov array - a part of the Yakutsk array.
The impact of green marketing on consumers’ attitudes: A moderating role of green product awareness
Authors: Sahioun Antoun , Q. Bataineh Abdallah , A. Abu-AlSondos Ibrahim , Haddad Hossam
Published: September 2023

This study aims to determine the impact of green marketing (green perceived value), green products (green buildings), and environmental concerns on Jordanian consumers’ attitudes toward buying green buildings in Jordan. The research population includes all consumers in Amman, the capital of Jordan, who might be interested in buying such buildings. A convenience sample is used to collect data from the respondents by distributing the questionnaire among 400 consumers using Google Forms. 357 questionnaires were found valid for statistical analysis. The results of the multiple regression test showed that R equals 0.815, which indicated that green marketing and consumers’ attitudes toward buying green buildings in Jordan are positively and highly correlated, with a percentage of 81.5%. R square equals 0.664, indicating that the variation in green marketing explains 66.4% of the variance in consumers’ attitudes toward green buildings in Jordan. Moreover, the hierarchical multiple regression test showed that there is an increase in R and R2 values in the existence of product awareness as a moderating variable between green marketing and consumers’ attitudes toward buying green buildings in Jordan.
Development of an Electroanalytical Method for Ronidazole Determination in Environmental and Food Matrices Using Boron-Doped Diamond Electrode
Authors: Bettio Guilherme , Okumura Leonardo , Silva Renê , Silva Tiago
Published: September 2023

A novel electroanalytical approach is presented for the determination of ronidazole in environmental and food matrices by applying a cathodically pretreated boron-doped diamond electrode and the square-wave adsorptive cathodic stripping voltammetry technique. From the studies of cyclic voltammetry to investigate the electroactivity of the ronidazole molecule, the occurrence of an irreversible cathodic process was verified, which was more efficiently detected using the cathodically pretreated boron-doped diamond electrode compared to the anodically pretreated electrode. Still on the electrochemical response of ronidazole, the effects of pH and scan rate were studied and, its apparent diffusion coefficient was determined by chronoamperometry (8.20 × 10−6 cm2 s−1). Under optimal experimental conditions, the analytical curve obtained for ronidazole was linear in two concentration ranges (12.70 to 63.40 µmol L−1 and 76.04 to 126.2 µmol L−1), with a limit of detection of 2.55 µmol L−1. For intra- and inter-day repeatabilities, relative standard deviations of only 2.7 and 3.5% were verified, which demonstrated the stable analytical response of the electrode. Recovery percentages ranging from 96 to 100% were achieved in the analysis of natural water and whole milk samples. Therefore, the proposed electroanalytical method shows satisfactory analytical performance towards ronidazole determination in varied matrice samples.