bluuebunny/crossref_metadata_2025 huggingface dataset:
تحليل محتوى كتاب "دروس اللغة العربية لغير الناطقين بـها" لعبد الرحيم (دراسة تحليلية مبنية على نظرية ماجكي (Mackey’s Theory)
Authors: Yany Liesty Fridari , M. Miftahul Ulum
Published: August 2022

Bahan ajar yang sangat diperlukan baik bagi guru maupun siswa adalah buku teks. Teori Mackey menyatakan bahwa buku teks harus memenuhi empat syarat yaitu seleksi, gradasi, presentasi, dan repetisi materi. Salah satu buku teks yang paling terkenal adalah Duruus al Lughah al Arabiyyah li Ghairi an Nathiqiina Bihaa karya Abd al-Rahim. Buku ini digunakan untuk mengajar bahasa Arab dalam program I’dad Lughawy di Universitas Islam Madinah. Penelitian ini bertujuan untuk mengetahui sejauh mana kesesuaian antara isi buku tersebut dengan teori Mackey. Pendekatan dalam penelitian ini menggunakan pendekatan kepustakaan. Jenis penelitian yang peneliti gunakan dalam penelitian ini adalah analisis buku teks.. Dan penggunaan teknik analisis data berupa analisis isi. Hasil dari penelitian ini adalah: 1) Materi buku sesuai dengan kriteria seleksi materi teori mackey ditinjau dari tujuan program, tingkat kemampuan siswa, dan jenis bahasa yang digunakan. 2) Gradasi dalam pengelompokan materi buku ini sudah memadai dengan menggunakan pengelompokan struktural dan pengelompokan semantik pada aspek pengelompokan materi berdasarkan fungsi, tetapi tidak menggunakan pengelompokan berdasarkan situasi. Dari segi pengurutan, materi buku ini sesuai dengan prinsip psikologi pendidikan, yaitu penyusunan materi dari umum ke khusus. 3) Presentasi materi yang digunakan adalah prosedur ostensif, prosedur pictoral, prosedur kontekstual. Buku ini tidak menggunakan prosedur diferensiasi karena materi dalam buku ini seluruhnya berbahasa Arab dan tidak ada bahasa ibu peserta didik.  4) Pada segi repetisi, setelah hiwar, qira’ah dan kitabah ada latihan yang berhubungan dengan materi, dan dari sisi istima’, peneliti tidak menemukan materi yang berhubungan dengan menyimak, sehingga buku ini tidak mengandung repetisi materi istima’.
دافعية تعلم اللغة العربية لدى طالبات المعهد
Authors: Ellizha Ellizha Andharisma , Moh. Munir
Published: August 2022

Penelitian ini bertujuan untuk menjelaskan motivasi Intrinsik dan Ekstrinsik yang dimiliki oleh santriwati pada program Takhosus Tahfidzul Qur’an dan implikasinya terhadap pembelajaran bahasa Arab. Penelitian ini merupakan penelitian kualitatif dengan menggunakan model studi analisis lapangan.  Metode pengumpulan data yang digunakan oleh peneliti adalah metode observasi, wawancara, dan dokumentasi. Sedangkan teknik analisis data yang digunakan adalah teknik analisis data milik Miles dan Huberman yang terdiri dari reduksi data, display data, dan kesimpulan. Sesuai dengan teori motivasi belajar milik Hamzah B. Uno, maka hasil penelitian menunjukkan bahwa Motivasi Intrinsik yang yang dimiliki santriwati Takhosus dalam belajar bahasa Arab yaitu adanya hasrat dan keinginan untuk berhasil sehingga mereka menyukai mata pelajaran bahasa Arab, adanya dorongan dan kebutuhan untuk belajar yang ditandai dengan keinginan mereka untuk menguasai bahasa Arab dan kebutuhan sebagai seorang muslim untuk memahami agamanya dan melaksanakan ibadah serta memudahkan mereka dalam menghafal Al-Qur’an, adanya harapan dan cita-cita di masa depan yaitu keinginan mereka untuk menjadi seorang penerjemah. Motivasi Ekstrinsik yang dimiliki santriwati Takhosus dalam belajar bahasa Arab yaitu Adanya penghargaan dalam belajar yang diberikan oleh guru saat pembelajaran berlangsung, adanya kegiatan yang menarik dalam belajar, adanya lingkungan bahasa yang diciptakan untuk mengfokuskan santriwati dalam belajar bahasa. Motivasi memiliki keterkaitan dan hubungan secara langsung dengan pembelajaran. Sehingga adanya motivasi dalam belajar bahasa Arab merupakan salah satu syarat yang harus dipenuhi agar peserta didik berhasil melewati proses pembelajaran.
IMPLEMENTASI PENDIDIKAN KARAKTER DI SEKOLAH ALAM PADA MASA PANDEMI COVID-19 (STUDI KASUS DI MI PELANGI ALAM PONOROGO)
Authors: Khoiri robihatul musayadah  , Evi Muafiah
Published: August 2022

Pendidikan memiliki dua tujuan penting yaitu untuk membentuk dan meningkatkan pengetahuan dan membuat seseorang menjadi lebih baik. Pendidikan sebagai salah satu sarana dalam mentransfer nilai-nilai serta pembentukan karakter bagi masyarakat. Sekolah alam merupakan sekolah inklusi dengan pembelajaran yang dilakukan dengan mengintegrasikan karakter-karakter tertentu yang ingin dibentuk sesuai dengan tujuan instansi pendidikan. Masa pandemi menjadi salah satu tantangan tersendiri bagi sekolah alam dalam membentuk karakter siswanya. Penelitian ini bertujuan untuk mendeskripsikan bagaimana pelaksanaan pembelajaran berbasis karakter di MI Pelangi Alam Ponorogo pada masa pandemi Covid-19. Penelitian ini mengunakan pendekatan penelitian kualitatif dengan jenis penelitian studi kasus. Temuan yang dihasilkan dari penelitian ini antara lain: pelaksanaan pembelajaran karakter di MI Pelangi Alam pada masa pandemi Covid-19 dilaksanakan dengan berbasis modul, memaksimalkan peran orang tua, pemilihan media belajar dan tema disesuaikan dengan kondisi pada masa pandemi, serta evaluasi dilaksanakan secara langsung dan online.
IMPLEMENTASI KEBIJAKAN PENDIDIKAN DINIYAH FORMAL DI MADRASAH COKROKERTOPATI TAKERAN MAGETAN
Authors: Ulil Abshor  , Aksin
Published: August 2022

Kementrian Agama Indonesia telah mengumumkan Kebijakan Pendidikan Diniyah Formal pada tahun 2015. Melalui kebijakan ini, pesantren dapat memformalkan pendidikan keagamaannya dan dapat menyediakan pelayanan pendidikan spesialisasi keagaamaan Islam. Dalam 5 tahun, kebijakan ini memiliki permasalahan implementasi yang strategis untuk dikaji demi efektifitas Pendidikan Diniyah Formal ke depan. Tujuan Penelitian ini untuk menganalisis kritis implementasi kebijakan Pendidikan Diniyah Formal ditinjau dari komunikasi, sumber daya, disposisi dan struktur birokrasi. Dan mendeskripsikan implementasi input dan proses pendidikan di madrasah. dan implikasinya terhadap lembaga. Dalam penelitian kualitatif ini, kondisi lapangan diuraikan dengan metode induktif melalui  pendekatan kebijakan pendidikan dan manajemen pendidikan. Wawancara, pengamatan dan analisis dokumen digunakan untuk pengumpulan data. Fokus penelitian ini adalah  Cokrokertopati yang  merupakan salah satu madrasah penerima  program pilot project dari pemerintah untuk menyelenggarakan Pendidikan Diniyah Formal pada tahun 2015. Hasilnya, Pertama dari segi implementasi kebijakan,  penyelenggaraan Pendidikan Diniyah Formal harus dibarengi dengan pengawalan, pembinaan dan kordinasi, terdapat komunikasi yang belum terstruktur dan berjenjang antara pemangku kebijakan dengan pelaksana kebijakan atau antara pelaksana kebijakan dengan pelaksana kebijakan yang lain, sumber daya yang kurang memadai, disposisi antara pemangku kebijakan dengan pelaksana kebijakan, rentang kendali struktur birokrasi yang belum terstruktur. Kedua dari segi input dan proses di madrasah, pengelolaan madrasah masih membutuhkan pengendalian mutu, dari segi input  beberapa tenaga pendidik belum memenuhi standar kualifikasi akademik, standar kurikulum terlalu tinggi, anggaran dana kurang memadai. sementara dari segi proses, madrasah belum  terkelola  dengan baik,  manajemen  proses pembelajaran belum memenuhi standar profesional, metode pembelajaran tidak variatif, penilaian hasil pembelajaran belum memenuhi standar profesional. Ketiga implikasi penyelenggaraan Pendidikan Diniyah Formal terhadap lembaga adalah paradigma formalisasi Pendidikan Diniyah, sentralisasi pesantren dan segmentasi pelayanan pendidikan spesialisasi keagamaaan Islam di madrasah.
MEMBENTUK PERILAKU KEAGAMAAN MELALUI MANAJEMEN MUATAN LOKAL ASWAJA DI MADRASAH ALIYAH PUTRI MA’ARIF PONOROGO
Authors: Ilham Alfa Rizqi  , Evi Muafiah
Published: August 2022

Saat ini, di Indonesia, banyak perilaku keagamaan umat beragama yang dapat mengganggu negara dan ketentraman negara. Dalam menghadapi problematika yang sedang dihadapi oleh masyarakat Indonesia, penanaman aspek spiritual siswa dianggap sebagai salah satu solusi dalam mencegah perpecahan dalam sebuah negara. Lembaga pendidikan ma’arif merupakan salah satu lembaga dengan ciri khas penyelenggaraan pendidikan dengan fokus pada penanaman pengetahuan dan akhlakul karimah (spiritual) yang disesuaikan dengan ahlus sunnah wal jama’ah melalui pembelajaran muatan lokal. Penelitian ini bertujuan untuk mendeskripsikan bagaimana perencanaan,pelaksanaan,dan evaluasi kurikulum muatan lokal dalam membentuk perilaku keagamaan di Madrasah Aliyah Putri Ma’arif Ponorogo. Penelitian ini mengunakan pendekatan penelitian kualitatif dengan jenis penelitian studi kasus. Temuan yang dihasilkan dari penelitian ini antara lain:  1) perencanaan muatan lokal yang dikembangkan di MA Putri Ma’arif Ponorogo dengan menentukan mata pelajaran, menetapkan guru, serta menetapkan sumber dana dan sumber belajar ; 2) Pelaksanaan kurikulum muatan lokal di MA Putri Ma’arif Ponorogo termanifestasi dalam bentuk kegiatan yang dilakukan oleh guru seperti mengkaji silabus, menyusun RPP, dan menyusun penilaian. Untuk memperdalam materi yang ada, terdapat kegiatan pembiasaan-pembiasaan yang dilaksanakan dalam jangka harian, mingguan, bulanan, dan tahunan seperti pembacaan surat-surat Jami’as-Syarif dan sholawat, sholat Dhuha dan sholat Dhuhur berjama’ah, khataman al-Qur’an, ziarah makam, istighosah, dll; 3) Evaluasi kurikulum muatan lokal di MA Putri Ma’arif Ponorogo dilakukan melalui evaluasi program muatan lokal dan evaluasi hasil belajar muatan lokal. Evaluasi program muatan lokal terdiri atas evaluasi reflektif, formatif, dan sumatif. Sedangkan evaluasi hasilbelajar muatan lokal terdiri atas tes tertulis dan tes lisan.
STRATEGI PENGEMBANGAN PROGRAM TAHFIDZ DALAM MENINGKATKAN DAYA SAING DI MADRASAH DINIYAH (Studi Kasus di Madrasah Diniyah Al-BAzariyyah Tempursari Wungu Madiun)
Authors: Dina  , Umi Rohmah
Published: August 2022

Tujuan Penelitian untuk: (1) Menjelaskan komponen apa saja yang dikembangkan dalam program Tahfidz di Madrasah Diniyah Al-Bazariyyah Tempursari Wungu Madiun dalam meningkatkan daya saing, (2) menjelaskan strategi pengembangan program tahfidz di Madrasah Diniyah Al-Bazariyyah Tempursari Wungu Madiun dalam meningkatkan daya saing, ( 3) menjelaskan dampak pengembangan program bagi santri di Madrasah Diniyah Al-Bazariyyah Tempursari Wungu Madiun. Penelitian ini menggunakan pendekatan kualitatif dengan deskripsi analisis, yaitu, deskripsi naratif dari proses perilaku subjek sesuai dengan masalah yang diteliti. Desain penelitian menggunakan studi kasus observasi yang terkait dengan strategi pengembangan kurikulum di Madrasah Diniyah Al-Bazariyyah Tempursari Wungu Madiun. Teknik pengumpulan data adalah: (1) wawancara mendalam, (2) observasi, (3) studi dokumentasi. Teknik analisis data menggunakan teknik deskriptif dengan tiga langkah (1) Data Reduction atau reduksi data, (2) Data Display atau penyajian data dan (3) menarik kesimpulan. Untuk memverifikasi validitas data untuk mendapatkan temuan penelitian yang valid dan dapat dipertanggungjawabkan kebenarannya menggunakan tehnik: (1) memperpanjang periode pengamatan, (2) pengamatan berkelanjutan dan (3) triangulasi. Temuan penelitian di Madrasah Diniyah Al-Bazariyyah Tempursari Wungu Madiun adalah (1) komponen pengembangan program Tahfidz Al-qur’an meliputi a). Perencanaan pembelajaran tahfidz Al-qur’an b). Pelaksanaan pembelajaran tahfidz Al-qur’an c). Evaluasi pembelajaran tahfidz Al-qur’an. (2) Strategi Pengembangan program Tahfidz Al-qur’an meliputi  a). Pengembangan pada tingkat lembaga, yang meliputi perumusan tujuan lembaga, menetapkan isi dan struktur program b). Pengembangan program setiap pelajaran, c). pengembangan program pembelajaran di kelas. (3) Dampak pengembangan program berpengaruh penting untuk membentuk karakter santri dalam kehidupannya seperti disiplin, berprestasi, mandiri, berakhlaqul karimah dan jujur.
Supervisi Kepala Sekolah dalam Rangka Pengembangan Kompetensi Profesional Guru di SMAIT Al Huda Wonogiri
Authors: Kuncoro Sigit , Kolis Nur
Published: August 2022

Pengembangan kompetensi profesional guru merupakan suatu keharusan, mengingat guru merupakan garda terdepan dalam pembelajaran. Jenis penelitian ini adalah penelitian kualitatif dengan jenis studi kasus Karena penelitian ini mempunyai latar subjek suatu kejadian di SMAIT AL Huda Wonogiri. Data bersumber dari data primer dan sekunder. Teknik pengumpulan data menggunakan observasi, wawancara dan studi dokumentasi. Hasil penelitian ini adalah teknik supervisi  yang digunakan oleh kepala SMAIT Al Huda yaitu teknik supervisi   perseorangan meliputi kunjungan kelas virtual, observasi kelas dan kroscek kepada siswa. Serta teknik supervisi kelompok meliputi rapat dan mengadakan diskusi kelompok. Usaha pengembangan kompetensi profesional guru yaitu peningkatan kompetensi profesional guru dalam merencanakan pembelajaran, peningkatan kompetensi profesional guru dalam pelaksanaan pembelajaran, peningkatan kompetensi profesional guru dalam evaluasi pembelajaran. Sedangkan usaha pengembangan kompetensi profesional guru yaitu kajian pekanan, pembinaan hari senin, upgrading, penilaian kinerja guru (PKG), dan Musyawarah Guru Mata Pelajaran (MGMP). Kendala yang dihadapi dalam supervisi kepala SMAIT AL Huda Wonogiri yaitu tidak mengetahui langsung kondisi siswa, jaringan internet, tidak mengetahui respon siswa secara maksimal. Hasil supervisi  dilakukan kepada 2 guru yaitu ustadzah Putri Ratna Juwita, M.Pd. mendapat skor 49 dari skor maksimal 52 artinya sangat baik, sedangkan ustadzah Asritami Sinta Hapsari S.E. mendapat Skor 44 dari skor maksimal 52 artinya  baik.
الأخطاء في كتابة العدد والدعدود في الرسائل الجامعية
Authors: Sholihah Rina Hasna , Fata Zahrul
Published: August 2022

Institut Agama Islam Negeri Ponorogo adalah salah satu lembaga yang mengkhususkan dalam pembelajaran bahasa Arab. Dan syarat untuk mendapatkan gelar sarjana bagi mahasiswa Program Studi Bahasa Arab Institut Agama Islam Negeri Ponorogo adalah kemampuan mereka dalam menulis penelitian ilmiah (skripsi) dalam bahasa arab yang baik dan benar sesuai dengan aturan tata bahasa (sintaksis) dan morfologi. Adapun tujuan penelitian ini adalah penelitian kesalahan studi dalam penulisan ‘adad dan ma’dud pada skripsi mahasiswa strata 1 yang terpilih program pendidikan bahasa arab IAIN Ponorogo tahun ajaran 2017/ 2018. Penelitian ini merupakan penelitian kualitatif, karena jenis data yang dikumpulkan berupa kata-kata yang didapatkan melalui analisis dokumen. Peneliti menggunakan analisis data model Miles dan Huberman. Adapun hasil penelitian adalah sebagai berikut: 1) Kesalahan dalam penulisan ‘adad wal ma’dud pada skripsi mahasiswa pertama yaitu 21 kesalahan dari 70 kalimat yang menggunakan ‘adad wal ma’dud dengan prosentase 30%. 2) Kesalahandalam penulisan ‘adad wal ma’dud pada skripsi mahasiswa kedua yaitu 4 kesalahan dari 15 kalimat yang menggunakan ‘adad wal ma’dud dengan prosentase 26,7%. 3) Kesalahan dalam penulisan ‘adad wal ma’dud pada skripsi mahasiswa ketiga yaitu 14 kesalahan dari 91 kalimat yang menggunakan ‘adad wal ma’dud dengan prosentase 15,4%. 4) Kesalahan dalam penulisan ‘adad wal ma’dud pada skripsi mahasiswa keempat yaitu 21 kesalahan dari 62 kalimat yang menggunakan ‘adad wal ma’dud dengan prosentase 33,9%. 5) Kesalahan dalam penulisan ‘adad wal ma’dud pada skripsi mahasiswa kelima yaitu 28 kesalahan dari 62 kalimat yang menggunakan ‘adad wal ma’dud dengan prosentase 45,2%. Dan adapun analisis kesalahan, yang paling banyak analisis kesalahannya adalah kesalahan dalam penulisan ta’nisi al ‘adad wa tadzkirihi dan jumlahnya ada 58 kalimat.
Random Forest Ensemble Model for Reservoir Fluid Property Prediction
Authors: Adeeyo Yisa
Published: August 2022

Reservoir fluid PVT properties are measured in the laboratory for various use in reservoir engineering evaluation and estimation. Despite the indispensability of these PVT parameters, PVT lab data are seldomly available and if available may be unreliable. Instead, various empirical models have been developed and used in the industry. These empirical models are inherently inaccurate when used to predict PVT properties of fluid from different geological region with different depositional environment and fingerprint. Artificial Intelligence (AI) has evolved over the years and provided some algorithms with potentials to develop accurate predictive model for the prediction of bubblepoint pressure.

This work tested some AI algorithms, compared performances and choose random forest regression algorithm in developing a robust predictive model for the estimation of bubblepoint pressure.

Two thousand five hundred and twenty-two datasets obtained from oil reservoirs in different geographical locations were used for the feature scaling of input data, training and testing of the models. The independent variables, gas-oil ratio, temperature, oil density and gas density were confirmed to have key influence on the dependent variable Bubblepoint pressure

The random forest model developed uses ensemble learning approach, combines predictions from multiple machine learning algorithms by averaging all predictions to make a more accurate prediction. The ‘forest’ generated by the random forest algorithm was trained through bootstrap aggregating. This is an ensemble meta-algorithm that improves the accuracy of machine learning algorithms. Percentage data split was 70% training and 30% testing.

The reliability, accuracy and completeness of the predictive model capability were computed through performance indices such as the root mean square error (RMSE) and mean absolute error (MAE). The best network architecture was determined along with the corresponding test set RMSE, and Correlation coefficient.

Statistical and graphical error analysis of the results showed that the random forest model performed better than existing models with 0.98 correlation coefficients for bubblepoint pressure. Better accuracy of reservoir properties prediction could be achieved using this random forest reservoir fluid properties prediction model.
Multi-locus genome-wide association study for phosphorus use efficiency in a tropical maize germplasm
Authors: Zeffa Douglas Mariani , Júnior Luiz Perini , Delfini Jéssica , Marcos Antoni Wallace , Koltun Alessandra , Baba Viviane Yumi , Constantino Leonel Vinícius , Nogueira Alison Fernando , Moda-Cirino Vania , Scapim Carlos Alberto , Gonçalves Leandro Simões Azeredo
Published: August 2022

Background and aim
Phosphorus (P) is an essential macronutrient for maize (Zea mays L.) growth and development. Therefore, generating cultivars with upgraded P use efficiency (PUE) represents one of the main strategies to reduce the global agriculture dependence on phosphate fertilizers. In this work, genome-wide association studies (GWAS) were performed to detect quantitative trait nucleotide (QTN) and potential PUE-related candidate genes and associated traits in greenhouse and field trials under contrasting P conditions.
Methods
The PUE and other agronomy traits of 132 inbred maize lines were assessed in low and normal P supply through the greenhouse and field experiments and Multi-locus GWAS was used to map the associated QTNs.
Results
Wide genetic variability was observed among the inbred maize lines under low and normal P supply. In addition, we confirm the complex and quantitative nature of PUE. A total of 306 QTNs were associated with the 24 traits evaluated using different multi-locus GWAS methods. A total of 186 potential candidate genes were identified, mainly involved with transcription regulator, transporter, and transference activity.
Conclusions
Further studies are still needed to elucidate the functions and relevance of these genes regarding PUE. Nevertheless, pyramiding the favorable alleles pinpointed in the present study can be considered an efficient strategy for molecular improvement to increase maize PUE.
Natural Cellulosic Alfa fiber improved with environment-friendly treatment cementitious composites with a stable flexural strength
Authors: Helaili Sofiene , guizani achref , chafra moez
Published: August 2022

Using natural fibers in structural applications is the subject of much research in the scientific world. Natural fibers are bio-sourced, biodegradable, have a low carbon footprint, and have interesting mechanical properties. The lightness, tensile strength, and elongation before break make natural fibers suitable candidates to replace synthetic fibers. Sometimes, natural fibers must undergo heavy chemical treatment for the extraction of microfiber. This is not the case in this paper, which presents a first attempt to use esparto fiber in its raw state without heavy treatment without soda and bleach. In this paper, the raw esparto stem cut into short fibers is treated, then prepared and used as reinforcement in mortar. The mechanical properties of the esparto stems were identified, analyzed, and improved. The mechanical tests showed a weak adhesion between the mortar and Alfa. Also, excessive absorption of water by the stem induced a delay in the mortar's setting. Even with unsaturated stems, this phenomenon is observable. An improvement was applied to the natural Alfa stem to improve its adhesion and reduce the absorption of spillage water. For the first time, as a major innovation in natural fibers used for cementitious composites, a method is presented in this paper allowing the use of Alfa (esparto) fiber in a mortar while keeping the mechanical strength properties of the mortar. Test specimens 4x4x16 cm were made and reinforced with short fibers of 2 and 3 cm with different volume concentrations: 1%, 2%, and 5%. The flexural strength and compressive strength were determined experimentally. The results show that for the 1% concentration of short fibers of 3cm, the compressive strength is 26 MPa, which is almost identical to the strength of the control specimen equal to 26.03 MPa. Flexural strength of the improved fibers concentrated at 1%, 2%, and 5% reach nearly 4.75 MPa very close to the flexural strength of the control specimen, which is 5.57 MPa. The flexural strength doesn't decrease with treated Alfa fiber concentration increase: this is a unique case in which flexural strength doesn't decrease compared to other natural fibers results in the literature. In a conclusion, Alfa-treated short fibers can be used in secondary structural applications subject to compressive and light bending forces, for example, paving applications.
Role of darkness in the germination process and conversion of direct somatic embryos into plantlets: Micropropagation protocol enhancement study of date palm.
Authors: Abohatem Mansour , Ba-Asher Abdullah , Al-Duais Mohammed
Published: August 2022

All studies in date palm somatic embryogenesis focused on the germination of light and neglected the darkness effect on germination. Study of the effect of light and darkness incubation on germination of date palm somatic embryos led to the developing of an efficient new and simple procedure for inducing the direct date palm somatic embryos germination and conversion into plantlets. In vitro germination in darkness played a critical role in direct converting date palm somatic embryos into plantlets. Direct somatic embryos germinated in the darkness exhibit continuous growth leading to forming etiolation longitudinal stems and thin leaves, while somatic embryos germinated in the light show inhibition of longitudinal growth with the formation of short stems and green wide leaves. Darkness germination process had decreased significantly the conversion period of direct somatic embryos into plantlets to less than 12 weeks. Darkness incubation led to germination and elongation in one stage, while the incubation in the light required two stages the embryo germination stage then the elongation stage. Somatic embryos grown in darkness had more protein and less phenolic compounds than embryos grown in the light. These results had led to significantly decrease in the protocol period and modified the protocol stages of date palm somatic embryos germination and conversion into plantlets, ending with better germination and reduction of time and costs.
On dispersion curve coloring for mechanical metafilters
Authors: Nutarelli Federico , Gnecco Giorgio , Bacigalupo Andrea , De Bellis Maria Laura
Published: August 2022

This paper formalizes smooth curve coloring (i.e., curve identification) in the presence of curve intersections as an optimization problem, and investigates theoretically properties of its optimal solution. Morever, it presents a novel automatic technique for solving such a problem. Formally, the proposed algorithm aims at minimizing the summation of the total variations over a given interval of the first derivatives of all the labeled curves, written as functions of a scalar parameter. The algorithm is based on a first-order finite difference approximation of the curves and a sequence of prediction/correction steps. At each step, the predicted points are attributed to the subsequently observed points of the curves by solving an Euclidean bipartite matching subproblem. A comparison with a more computationally expensive dynamic programming technique is presented. The proposed algorithm is applied with success to elastic periodic metamaterials for the realization of high-performance mechanical metafilters. Its output is shown to be in excellent agreement with desirable smoothness and periodicity properties of the metafilter dispersion curves. Possible developments, including those based on machine-learning techniques, are pointed out.
Broadband Flat Amplification Based on Fully Double-Pass
Configuration in Serial Hybrid Fiber Amplifier
Authors: Ali Ali , Al-Mashhadani Mohammed Kamil Salh , Al-Mashhadani Thamer Fahad , Awsaj Mohammed , Bouteraa Yassine
Published: August 2022

A broadband amplification that utilizes a serial hybrid fiber amplifier is experimentally demonstrated in this paper. Two fully double-pass configurations, namely, setups A and B, are implemented. The difference between these two configurations is that the position of the two amplifiers (erbium and Raman) is swapped. These two configurations are tested under the same input parameter conditions. Two laser pump power wavelengths with a total pump power of 375 mW (1495 nm with 350 mW for Raman and 1480 nm with 25 mW for the erbium amplifier) were used. Under the optimum condition and under a small signal power of -30 dBm, a wide flatness gain bandwidth of 80 nm (1530–1610 nm) with an average gain level of 28.5 and 24 dB is achieved for setups A and B, respectively. A wide bandwidth is achieved by avoiding the amplification overlap between these two amplifiers through choosing the proper pump wavelength.
Discrimination of Normal and Cancerous Human Skin Tissues Based on Laser-Induced Spectral Shift Fluorescence Microscopy
Authors: Niazi Azadeh , Parvin Parviz , Jafargholi Amir , Basam Mohammad , Khodabakhshi Zahra , Bavali Ali , Hesari Kambiz Kamyab , Sohrabizadeh Zahra , Hassanzadeh Tara , Dizaj Leyla Shirafkan , Amiri Reza , Heidari Omid , Aghaei Mohammadreza , Atyabi Fatemeh , Ehtesham Alireza , Moafi Ali
Published: August 2022

A homemade spectral shift fluorescence microscope (SSFM) is coupled with a spectrometer to record the spectral images of specimens based on the emission wavelength. Here a reliable diagnosis of neoplasia is achieved according to the spectral fluorescence properties of ex-vivo skin tissues after Rd6G staining. It is shown that certain spectral shifts occur for nonmelanoma/melanoma lesions against normal/benign nevus, leading to spectral micrographs. In fact, there is a strong correlation between the emission wavelength and the sort of skin lesions, mainly due to the Rd6G interaction with the mitochondria of cancerous cells. The normal tissues generally enjoy a significant red shift regarding laser line. Conversely, plenty of fluorophores are conjugated to unhealthy cells giving rise to a relative blue shift against normal tissues or a smaller redshift with respect to the excitation wavelength. Consequently, three data sets are available in the form of micrographs, addressing pixel by pixel signal intensity, emission wavelength, and fluorophore concentration of specimens for prompt diagnosis.
An empirical study on entrepreneurial willingness and entrepreneurial rationality: based on an entrepreneurship questionnaire survey of Chinese college students
Authors: Xiao wensheng
Published: August 2022

Through researching the status of willingness and rationality of College Students' Entrepreneurship (CSE) in China, which have called on "Mass Entrepreneurship" since 2014, this study is to explore the influence of entrepreneurial willingness and entrepreneurial rationality on entrepreneurial success and the methods and measures to improve college students' entrepreneurial willingness and rationality, which contribute to improve the success rate of entrepreneurship, so as to improve the utilization efficiency of social resources and save social resources. Through 601 questionnaires on entrepreneurial understanding, combined with the basic situation of college students, such as college, major, grade, and gender, this research uses the methods of factor analysis and regression analysis to study the internal factors affecting CSE. The findings concluded that College Students' Founders (CSF) mainly focus on earnings, risks and capitals for entrepreneurship, and the main factors affecting college students' choice and success of entrepreneurship are relevant knowledge of entrepreneurship. Therefore, from the perspective of education, innovation-entrepreneurship education (IEE) should be focus on entrepreneurial willingness and entrepreneurial rationality, and should improve the pertinence and adaptability of entrepreneurship education, should strengthen entrepreneurship practice education, which start as soon as possible, according to the characteristics of the colleges and specific majors. These results extend the extant findings in the literature on entrepreneurial intention, practice. Also, this study can provide reference for the study of entrepreneurship education in world universities.
Low attainment to PK/PD-targets for β-lactams during the first 72 hours of treatment: a multicenter study of early Antibiotic Concentrations in Critically ill ICU patients in Sweden (ACCIS)
Authors: Smekal Anna-Karin , Furebring Mia , Eliasson Erik , Lipcsey Miklos
Published: August 2022

Background: Severe infections are life-threatening conditions commonly seen in the intensive care units (ICUs). Antibiotic treatment with adequate concentrations is of great importance during the first days when the bacterial load is the highest. Therapeutic drug monitoring (TDM) of β-lactam antibiotics has been suggested to monitor target attainment and to improve the outcome. Method: This prospective multi-centre study in seven ICUs in Sweden study investigated pharmacokinetic/pharmacodynamic-target (PK/PD-target) attainment for cefotaxime, piperacillin-tazobactam and meropenem, commonly used β-lactams in Sweden. A mid-dose and trough antibiotic concentration blood sample were taken from patients with severe infection daily during the first 72 hours of treatment. Antibiotic plasma concentrations were analysed by liquid chromatography-mass spectrometry (LC-MS). Antibiotic concentrations 100% time above MIC (minimal inhibitory concentration), (100% T>MIC) and four times above MIC 50% of the time (50%T>4xMIC) were used as PK/PD-targets. Results: We included 138 patients with the median age of 67 years and the median Simplified Acute Physiology Score 3 (SAPS3) of 59. Forty-five percent of the study-population failed to reach 100% T>MIC during the first day of treatment. The results were similar the following two days. There was a three-fold risk of not meeting the PK/PD target if the patient was treated with cefotaxime. For the cefotaxime treated patients 8 out of 55 had at least one end-dose concentrations below the level of detection during the study. Low age, low illness severity, low plasma creatinine, lower respiratory tract infection, cefotaxime treatment and renal replacement therapy were risk factors for not reaching 100%T>MIC.Conclusion: In Swedish ICU-patients treated with β-lactam antibiotics, a high proportion of patients did not reach the PK/PD target. TDM could identify patients that need individual higher dosing regimens already on the first day of treatment. Further studies on optimal empirical start dosing of β-lactams, especially for cefotaxime, in the ICU are needed.Trial registration: The protocol was retrospectively registered 100216 (ACTRN12616000167460).
Clinical Findings and Genetic Analysis of Patients with Copy Number Variants Involving 17p13.3 By Using a Single Nucleotide Polymorphism Array: A Single-Center Experience
Authors: Liang Bin , Yu Donghong , Zhao Wantong , Lin Na , Huang Hailong , Xu Liangpu
Published: August 2022

Background
17p13.3 microdeletions or microduplications (collectively known as copy number variants or CNVs) have been described in association with individuals with neurodevelopmental disorders. While, studies on 17p13.3 CNVs in prenatal diagnosis are limited. This study aims to investigate the clinical significance of 17p13.3 CNVs with varied size and gene contents in prenatal and postnatal samples.
Methods
Eight cases with 17p13.3 CNVs out of 8806 samples that had been subjected to single nucleotide polymorphism array analysis were retrospectively analyzed, along with karyotype, clinical features, and follow-up.
Results
Eight cases with 17p13.3 CNVs consisted of five fetuses, one abortion embryo and two probands manifested severe congenital defects. The prenatal findings varied significantly for the five fetuses, including ultrasound abnormalities (n = 3), segmental deletions indicated with non-invasive prenatal testing (n = 1), and pregnant women with intellectual disability (n = 1). Of them, two and six harbored copy number gains and losses involving 17p13.3, respectively. The size of the detected 17p13.3 CNVs ranged from 576 kb to 5.7 Mb. Case 1 was diagnosed with 17p13.3 duplication syndrome, and cases 4, 6, and 7 with Miller–Dieker syndrome (MDS). Microdeletions of the 17p13.3 region in two cases (cases 5 and 8) involving YWHAE and CRK, sparing PAFAH1B1, were classified as pathogenic. Case 2 harbored a 576 Kb microduplication, encompassing YWHAE and CRK but not PAFAH1B1, which was of maternal origin and considered a variant of uncertain significance. Case 3 had one large duplication spanning the partial short arm, centromere, and partial long arm, and two deletions at 17p13.3p13.2 and 17q25.3, which karyotype was 46,XY,r(17)(p13q25). For five fetuses, only case 2 continued gestation and showed a good outcome; the others were subjected to termination of pregnancy.
Conclusion
The clinical findings of 17p13.3 microdeletions or microduplications varied among subjects, and 17p13.3 CNVs often differ in size and gene contents. Microdeletions or microduplications containing the typical MDS region, as well as the microdeletions involving YWHAE and CRK, could be classified as pathogenic. The clinical significance of small duplications including YWHAE and CRK but not PAFAH1B1 remains uncertain, for which parental testing and clinical heterogeneity should be considered in genetic counseling.
Smart System Modeling and Simulation design of Hemodialysis Machine by SysML with SystemC-AMS
Authors: Abdulhameed Abbas , AlKindy Bassam , Al-Mahdawi Basil
Published: August 2022

The corrections of the large and complex systems have become an issue of great importance recently due to the system development process. The device technology is quite complex and encompasses various disciplines of engineering, medicine, biology, and critical patient-machine interfaces. In this paper, we proposed a simulation approach to the verification and validation of the system of the hemodialysis machine (HD machine) specified by the SysML language. The simulation is carried out through intelligent translation based on the specifications of SysML into SystemC-AMS models. To evaluate and validate the system design, they are translated into a set of formulas and requirements verified when run on the available tools, COSE DA technologies, the WSN simulator developed by SystemC-AMS
How to create value with unobtrusive monitoring technology in home-based dementia care: A multimethod study among key stakeholders
Authors: Wrede Christian , Braakman-Jansen Annemarie , Gemert-Pijnen Lisette van
Published: August 2022

Background: There is a growing interest to support extended independent living of people with dementia (PwD) via unobtrusive monitoring (UM) technologies which allow caregivers to remotely monitor lifestyle, health, and safety of PwD. However, these solutions will only be viable if developers obtain a clear picture of how to create value for all relevant stakeholders involved and achieve successful implementation. The aim of this study was therefore to explore the value proposition of UM technology in home-based dementia care and preconditions for successful implementation from a multi-stakeholder perspective.Methods: We conducted an expert-informed survey among potential stakeholders (n=25) to identify key stakeholders for UM technology in home-based dementia care. Subsequently, focus groups and semi-structured interviews were conducted among 5 key stakeholder groups (n=24) including informal caregivers (n=5), home care professionals (n=5), PwD (n=4), directors and managers within home care (n=4), and policy advisors within the elderly care and health insurance sector (n=6). The sessions addressed the value proposition- and business model canvas and were analyzed using thematic analysis. Results: Stakeholders agreed that UM technology should provide gains such as objective surveillance, timely interventions, and prevention of unnecessary control visits, whereas pains mainly included information overload, unplannable care due to real-time monitoring, and less human interaction. The overall design-oriented need referred to clear situation classifications including urgent care (fall- and wandering detection), non-urgent care (deviations in eating, drinking, sleeping), and future care (risk predictions). Most important preconditions for successful implementation of UM technology included inter-organizational collaboration, a shared vision on re-shaping existing care processes, integrated care ICT infrastructures, clear eligibility criteria for end-users, and flexible care reimbursement systems.Conclusions: Our findings can guide the value-driven development and implementation of UM technology for home-based dementia care. Stakeholder values were mostly aligned, although stakeholders all had their own perspective on what UM technology should accomplish. Besides, our study highlights the complexity of implementing novel UM technology in home-based dementia care. To achieve successful implementation, organizational and financial preconditions, as well as digital data exchange between home care organizations, will be important.
Reshaping the Path of Mild Cognitive Impairment by Refining Exercise Prescription: A Study Protocol of a Randomized Controlled Trial to Understand the “What”, “For Whom”, and “How” of Exercise to Promote Cognitive Function
Authors: Barha Cindy K. , Falck Ryan S. , Best John R. , Nagamatsu Lindsay S. , Hsiung Ging-Yuek Robin , Sheel A. William , Hsu Chun Liang , Kramer Arthur F. , Voss Michelle W. , Erickson Kirk I. , Davis Jennifer C. , Shoemaker J. Kevin , Boyd Lara , Crockett Rachel A. , Brinke Lisanne ten , Bherer Louis , Singer Joel , Galea Liisa A. M. , Jacova Claudia , Bullock Alexis , Grant Sofia , Liu-Ambrose Teresa
Published: August 2022

Background: Targeted exercise training is a promising strategy for promoting cognitive function and preventing dementia in older age. Despite the utility of exercise as an intervention, variation still exists in exercise-induced cognitive gains and questions remain regarding the type of training (i.e., what), as well as moderators (i.e., for whom) and mechanisms (i.e., how) of benefit. Both aerobic training (AT) and resistance training (RT) enhance cognitive function in older adults without cognitive impairment; however, the vast majority of trials have focused exclusively on AT. Thus, more research is needed on RT, as well as on the combination of AT and RT, in older adults with mild cognitive impairment (MCI), a prodromal stage for dementia. Therefore, we aim to conduct a 6-month, 2x2 factorial randomized controlled trial in older adults with MCI to assess the individual effects of AT and RT, as well as the combined effect of AT and RT on cognitive function and to determine the possible underlying biological mechanisms. Methods:Two hundred and sixteen community-dwelling adults, aged 65 to 85 years, with MCI from metropolitan Vancouver will be recruited to participate in this study. Randomization will be stratified by biological sex and participants will be randomly allocated to one of the four experimental groups: 1) 4x/week balance and tone (BAT; i.e., active control); 2) combined 2x/week AT + 2x/week RT; 3) 2x/week AT + 2x/week BAT; or 4) 2x/week RT + 2x/week BAT. The primary outcome is cognitive function as measured by the Alzheimer’s Disease Assessment Scale-Cognitive-Plus. Secondary outcomes include cognitive function, health related quality of life, physical function, actigraphy measures, questionnaires, and falls. Outcomes will be measured at baseline, 6 months (i.e., trial completion), and 18 months (i.e., 12-month follow-up). Discussion:Establishing the efficacy of different types and combinations of exercise training to minimize cognitive decline will advance our ability to prescribe exercise as “medicine” to treat MCI and delay the onset and progression of dementia. This trial is extremely timely as cognitive impairment and dementia pose a growing threat to global public health. Trial Registration: ClinicalTrials.gov, NCT02737878. Registered on April 14, 2016. https://clinicaltrials.gov/ct2/show/NCT02737878
Association of blood cadmium and metabolic syndrome: A cross-sectional analysis of National Health and Nutrition Examination Survey 2017-2020
Authors: Xing Weilong , Wang Lei , Gu Wen , Liang Mengyuan , Wang Zhen , Fan Deling , Zhang Bing
Published: August 2022

Previous findings have reported the role of different types of heavy metals in cardiometabolic diseases. In the present research, we aim to evaluate the association between blood cadmium levels and MetS base on the large-sample NHANES data. Public availably data from NHANES 2017–2020 cycle was obtained. Participants were divided into MetS and non-MetS groups according to waist circumference (WC), triglyceride (TG), high-density lipoprotein (HDL), blood pressure (BP) and fasting plasma glucose (FPG) levels based on the National Cholesterol Education Program (NCEP) criteria. Student’s t test, Mann-Whitney U test, and Chi-square test were performed for univariate analysis. Multivariate logistic analysis was performed to explore the relationship between blood cadmium and MetS and research findings were presented in forest plot. We also investigated the association of blood cadmium and MetS in subgroups stratified by age, gender and race. Population with MetS had significantly higher levels of blood cadmium compared with those without MetS [0.30 (0.18–0.54) vs. 0.24 (0.15–0.46) ug/L, p < 0.001]. Higher blood cadmium concentrations were also observed in participants with elevated WC, TG, BP and FPG compared with those with normal metabolic parameters. Multivariate logistic regression showed that one unit increasement of blood cadmium was associated with 1.25 times higher prevalence ratios for MetS after adjusting potential confounders (95% CI: 1.06–1.48, p = 0.0083). Stratified multiple logistic regression analysis indicated that the positive association between blood cadmium and MetS remained significant in subjects less than 60 years old and female subgroup. In conclusion, the cross-sectional survey suggested the positive association between blood cadmium levels and risk for MetS, prospective research need to be conducted for further evaluation of the causal relationship between blood cadmium and MetS.
Agile Maneuvers in Legged Robots: a Predictive Control Approach
Authors: Mastalli Carlos , Merkt Wolfgang , Xin Guiyang , Shim Jaehyun , Mistry Michael , Havoutis Ioannis , Vijayakumar Sethu
Published: August 2022

Planning and execution of agile locomotion maneu-vers have been a longstanding challenge in legged robotics. Itrequires to derive motion plans and local feedback policies inreal-time to handle the nonholonomy of the kinetic momenta.To achieve so, we propose a hybrid predictive controller thatconsiders the robot’s actuation limits and full-body dynamics. Itcombines the feedback policies with tactile information to locally predict future actions. It converges within a few millisecondsthanks to a feasibility-driven approach. Our predictive controllerenables ANYmal robots to generate agile maneuvers in realisticscenarios. A crucial element is to track the local feedback policiesas, in contrast to whole-body control, they achieve the desiredangular momentum. To the best of our knowledge, our predictivecontroller is the first to handle actuation limits, generate agilelocomotion maneuvers, and execute optimal feedback policies forlow level torque control without the use of a separate whole-bodycontroller.
Complex relationships inside the microbial communities of natural whey starters used for Parmigiano Reggiano cheese production revealed by culture-dependent and 16S rRNA metabarcoding portrait
Authors: Sola Laura , Quadu Emanuele , Bortolazzo Elena , Bertoldi Loris , Randazzo Cinzia L , Pizzamiglio Valentina , Solieri Lisa
Published: August 2022

Natural whey starters (NWS) are undefined microbial communities produced daily from whey of the previous cheese-making round, by application of high temperature. As a result, in any dairy plant, NWS are continuously evolving, undefined mixtures of several strains and/or species of lactic acid bacteria, whose composition and performance strongly depend on the selective pressure acting during incubation. While NWS is critical to assure consistency to cheese-making process, little is known about the composition, functional features, and plant-to-plant fluctuations. Here, we integrated culture-dependent methods and 16S rRNA metabarcoding to profile microbial communities of 10 NWS sampled in the production area of Parmigiano Reggiano cheese. 16S rRNA metabarcoding analysis revealed two main NWS community types, namely NWS type-H and NWS type-D, with Lactobacillus helveticus being more abundant in NWS type-H and Lactobacillus delbrueckii/St. thermophilus in NWS type-D, respectively. Based on prediction of metagenome functions, NWS type-H samples have enriched functional pathways related to galactose catabolism and purine metabolism, while NWS type-D were enriched in pathways related to aromatic and branched chain amino acid biosynthesis, which are flavor compound precursors. Culture-dependent approaches reveled low cultivability of individual colonies as axenic cultures and high genetic diversity in the pool of cultivable survivors. Co-culturing experiments showed that fermentative performance decreases by reducing the microbial complexity of inoculum, suggesting that complex biotic interactions and cross-feeding relationships take place in NWS communities, assuring phenotypic robustness. Even though our data cannot directly predict these ecological interactions, this study provides the basis for experiments targeted at understanding how selective regime affects NWS composition, microbial interaction, and technological features.