bluuebunny/crossref_metadata_2025 huggingface dataset:
Learning from a Feasibility Trial of a Simple Intervention: Is Research a Barrier to Service Delivery, or is Service Delivery a Barrier to Research?
Authors: Frost Julia , Britten Nicky
Published: March 2020

(1) Background: Applied health services research (AHSR) relies upon coordination across multiple organizational boundaries. Our aim was to understand how competing organizational and professional goals enhance or impede the conduct of high quality AHSR. (2) Methods: A qualitative study was conducted in two local health care systems in the UK, linked to a feasibility trial of a clinic-based intervention in secondary care. Data collection involved 24 semi-structured interviews with research managers, clinical research staff, health professionals, and patients. (3) Results: This study required a dynamic network of interactions between heterogeneous health and social care stakeholders, each characterized by differing ways of organizing activities which constitute their core functions; cultures of collaboration and interaction and understanding of what research involves and how it contributes to patient care. These interrelated factors compounded the occupational and organizational boundaries that hindered communication and coordination. (4) Conclusions: Despite the strategic development of multiple organizations to foster inter-professional collaboration, the competing goals of research and clinical practice can impede the conduct of high quality AHSR. To remedy this requires the alignment and streamlining of organizational goals, so that all agencies involved in AHSR develop a shared understanding and mutual respect for the progress of evidence-based medicine and the complex and often nuanced environments in which it is created and practiced.
Modelling Consciousness within Mental Monism: An Automata-Theoretic Approach
Authors: Lloyd Peter
Published: March 2020

Models of consciousness are usually developed within physical monist or dualistic frameworks, in which the structure and dynamics of the mind derive from the workings of the physical world (in particular, the brain). Little attention has been given to modeling within a mental monist framework, deriving the structure and dynamics of the mental world from primitive mental constituents only. Mental monism is gaining attention as a candidate solution to Chalmers’ Hard Problem, and it is therefore timely to examine possible formal models of consciousness within it. Here, we propose a minimal set of hypotheses that any credible model of consciousness (within mental monism) should respect. From those hypotheses, it is feasible to construct many formal models that permit universal computation in the mental world, through cellular automata. We need further hypotheses to define transition rules for particular models, and we propose a transition rule with the unusual property of deep copying in the time dimension. In conclusion, we hope to dispel the notion that mental monism requires a deus ex machina, by showing that a parsimonious set of assumptions can yield a naturalistic and computationally potent mental world.
Recent Progressive Use of Advanced Atomic Force Microscopy in Polymer Science: A Review
Authors: Nguyen-Tri Phuong , Ghassemin Payman , Carriere Pascal , Assadi Aymen Amine , Nguyen Dinh Duc
Published: March 2020

Atomic force microscopy (AFM) has been extensively used for the nanoscale characterization of polymeric materials. The coupling of AFM with infrared spectroscope (AFM-IR) provides another advantage to the chemical analyses and thus helps to shed light upon the study of polymers. In this perspective paper, we review recent progress in the use of AFM-IR in polymer science. We describe first the principle of AFM-IR and the recent improvements to enhance its resolution. We discuss then the last progress in the use of AFM-IR as a super-resolution correlated scanned-probe IR spectroscopy for chemical characterization of polymer materials dealing with polymer composites, polymer blends, multilayers and biopolymers. To highlight the advantages of AFM-IR, we report here several results in studying crystallization of both miscible and immiscible blends as well as polymer aging. Then, we demonstrate how this novel technique can be used to determine phase separation, spherulitic structure and crystallization mechanisms at the nanoscale, which have never been achieved before. The review also discusses future trends in the use of AFM-IR in polymer materials, especially in polymer thin film investigation.
Intra- and Inter-Rater Reliability of a Ballet-based Dance Technique Screening Instrument
Authors: Bronner Shaw , Lassey Ivetta , Lesar Jessie R , Shaver Zachary G , Turner Catherine
Published: March 2020

OBJECTIVES: To investigate intra- and inter-rater reliability of a ballet-based Dance Technique Screening Instrument used by physical therapists (PTs) and student PTs (SPTs) with prior dance medicine or dance experience. METHODS: Ten pre-professional dancers were video-recorded in the
sagittal and frontal planes while performing four dance sequences: 1) second position grand plié; 2) développé à la seconde; 3) single-limb passé relevé balance; and 4) jumps in first position. Dance videos and electronic versions of the demographics
and scoring forms were provided through a secure online survey to 28 PTs and SPTs who served as raters. Raters reviewed a training video prior to scoring the 10 dancers. Raters were asked to repeat their assessments 1–2 wks later. Intraclass correlations (ICC) were assessed for all-raters,
PTs, and SPTs for total and sequence scores. RESULTS: Twenty-eight raters assessed the videos one time. Inter-rater reliability was ICC=0.98 (CI95=0.96–0.99) (all-raters), with PTs and SPTs displaying similar values (ICC=0.96 and 0.96, respectively). Eighteen raters (11 PTs, 7 SPTs)
repeated the video analysis. Intra-rater reliability was ICC=0.78 (CI95=0.72–0.83) with PTs ICC=0.81 and SPTs ICC=0.70. CONCLUSIONS: Correlations were high for all-raters. SPTs were as reliable as PTs in inter-rater comparisons. PTs exhibited higher intra-rater reliability compared to
SPTs. These results substantiate the reliability of a standardized testing instrument to conduct dance technique assessment. Validity of this instrument was demonstrated in a previous study which found dancers with better technique were less likely to sustain injury. The ability to identify
technique deficits can guide preventative programs that may reduce injury risk. LEVEL OF EVIDENCE: Level III.
Corporate Social Responsibility (Csr) Dan Good Corporate Governance (Gcg) Sebagai Indikator Dalam Menilai Nilai Perusahaan
Authors: Hadyarti Vidi , Mahsin Tubagus M
Published: March 2020

Berbagai macam pendekatan dalam pengukuran nilai perusahaan sudah banyak digunakan dalam berbagai penelit ianpenelitian ilmiah. Hal ini menunjukkan berbagai pemikiran tentang nilai perusahaan, suatu nilai perusahaan yang menggambarkan kondisi suatu perusahaan selama beroperasi. Nilai perusahaan pent ing diketahui karena semakin t inggi nilai perusahaan menunjukkan kemakmuran para pemegang saham.  Tulisan ini memcoba untuk menulis kembali pemaparan tentang Corporate Social Responsibilit y (CSR) dan Good CorporateGovernance (GCG) sebagai salah satu indikator pengukuran nilai perusahaan. Suatu pendekatan yang bisa mempresentasikan makna yang lebih besar dari gambaran kondisi suatu perusahaan, sehingga sampai saat ini CSR dan GCG masih menjadi indikator bagi penelit i dalam pengukuran nilai perusahaan.
Pengaruh Ekuitas Merek Terhadap Keputusan Memilih Dengan Minat Sebagai Variabel Intervening
Authors: Rido Fathur , AS Fathor , Purnamawati Purnamawati
Published: March 2020

Tujuan dari penelit ian ini adalah (1) untuk mengetahui pengaruhsignifikan ekuitas merek terhadap minat mahasiswa memilihUniversitas Trunojoyo Madura, (2) untuk mengetahui pengaruhsignifikan ekuitas merek terhadap keputusan mahasiswamemilih Universitas Trunojoyo Madura, (3) untuk mengetahuipengaruh signifikan minat memilih terhadap keputusanmahasiswa memilih Universitas Trunojoyo Madura, (4) untukmengetahui pengaruh secara signifikan ekuitas merek terhadapkeputusan memilih Universitas Trunojoyo Madura melaluiminat memilih sebagai variabel intervening. Metode penelit ianini adalah metode kuantitatif dengan jumlah sampel sebesar 98responden dengan tehnik sampel yang digunakan adalahProportinate stratified random sampling,data respondendiperoleh dengan menggunakan kuisioner, Analisis yangdigunakan adalah analisis jalur (path analysis). Hasil analisismenunjukkan bahwa (1) ekuitas merek berpengaruh signifikansecara langsung terhadap minat memilih, (2) ekuitas merekberpengaruh signifikan secara langsung terhadap keputusanmemilih, (3) minat memilih berpengaruh signifikan secaralangsung terhadap keputusan memilih, (4) ekuitas merekberpengaruh signifikan secara tidak langsung terhadapkeputusan memilih melalui minat memilih. Hasil penelit ianmenyimpulkan bahwa ekuitas merek telah mampu meciptakankeputusan dan minat memilih Universitas Trunojoyo Madurabaik secara langsung maupun tidak langsung.
DAMPAK DAN TANTANGAN DALAM IMPLEMENTASI SOCIAL MEDIA MARKETING UNTUK UMKM
Authors: Chrismardani Yustina , Setiyarini Triana
Published: March 2020

Social media marketing merupakan variasi alat pemasaran yang dapat digunakan secara mudah dan tidak berbiaya, bila dibandingkan dengan alat pemasaran lainnya. Dengan biaya yang lebih rendah daripada alat pemasaran yang lain, UMKM cenderung cocok menggunakan metode social media marketing untuk memperkenalkan produknya, membangun hubungan dengan pelanggan dan memperkuat merk nya. Pada kenyatannya, hanya 30% usaha di Indonesia yang menggunakan instrument digital, sehingga dibutuhkan lebih banyak riset untuk mengeksplorasi perspektif dari perusahaan, terutama dalam memahami penghalang atau penghambat dalam penggunaan social media marketing. Tujuan dari riset ini adalah mendeskripsikan konsep social media marketing, penggunaan social media sebagai sarana promosi untuk UMKM, dampak dan tantangan dihadapi oleh UMKM dalam penggunaan social media. Merencanakan untuk menggunakan social media sebagai alat pemasaran yang kompetitif, memerlukan isi pesan yang dapat menarik perhatian pelanggan. Selain itu, juga dibutuhkan ketulusan, perhatian dan respon dengan cepat dalam berkomunikasi dengan pelanggan target. Tantangan dalam penggunaan social media marketing oleh UMKM yang meliputi factor internal dan eksternal, merupakan hal yang harus dihadapi dan diantisipasi agar mencapai keberhasilan dalam social media marketing.
Forecasting and Analysis of Time Variation of Parameters of COVID-19 Infection in China Using An Improved SEIR Model
Authors: Zhang Guoping , Pang Huaji , Xue Yifei , Zhou Yu , Wang Ruliang
Published: March 2020

Background: Due to the emergency pandemic threat, the COVID-19 has attracted widespread attention around the world. Common symptoms of infection were fever, cough, and myalgia fatigue. On January 31, 2020, the World Health Organization (WHO) declares this outbreak a Public Health Emergency of International Concern (PHEIC).Methods: In order to study the spread of the novel coronavirus pneumonia, this paper proposed an improved SEIR model to simulate the spread of the virus, which includes the effect factor of government intervention. The model parameters are determined based on the daily reported statistical data (up to February 8) of confirmed, suspected, cured, and death. According to utilize the spread rate, the probability of infection of the suspected, the probability of the suspected becoming a confirmed one, the cure rate, the mortality rate, and the quarantine ratio, we performed simulations and parameter calibrations at three region levels, i.e., China, Hubei and non-Hubei respectively. In addition, considering that the government initiated effective prevention and control measures after the outbreak, this paper dynamically estimates all the parameters of the proposed model.Results: The simulation reveals that the parameters of non-Hubei region are not significantly different from Hubei’s. Hubei Province has a high transmission rate, low cure rate, high probability of infection, low effective quarantine rate. since January 31, with the continuous strengthening of epidemic prevention and control measures, all parameters of the model have changed significantly. The parameters of Hubei and non-Hubei regions have the same trend. The trend of all parameters is now moving in a direction that is conducive to reducing the number of confirmed, suspected and fatal cases.Conclusions: The number of infections of the virus initially showed a rapid increase in the trend, and the number of infectious case showed a clear downward shape. With the government to take a variety of prevention and control measures and the efforts of the general medical staff, the number of infection curve on February 22 appeared in the top of the arc pattern, indicating that the inflection point began to appear, but the decline in the number of infections slowly.
Red and white meat intake in relation to mental disorders in adults
Authors: Kazemi Shiva , Keshteli Ammar Hassanzadeh , Saneei Parvane , Afshar Hamid , Esmaillzadeh Ahmad , Adibi Peyman
Published: March 2020

Background The association between meat intake and mental disorders are less investigated and the findings are contradicting. We aimed to examine the association between meat intake and depression, anxiety and psychological distress in Iranian adults. Methods This cross-sectional study included 3362 subjects with 18-55 years old. A dish-based 106-item semi-quantitative food frequency questionnaire (FFQ), Hospital Anxiety and Depression Scale (HADS), General Health Questionnaire (GHQ), all validated in Iranian population, were applied to collect data on meat intake, anxiety, depression and psychological distress, respectively. Results The prevalence of depression, anxiety and psychological distress in the study population was 28.6, 13.6 and 22.6%, respectively. After considering potential confounders, individuals in top quartile of red meat intake had 43% increased risk of depression (OR=1.43; 95%CI: 1.09-1.89), compared to the first quartile. No significant relationship was observed between red meat intake and anxiety or psychological distress. White meat intake was not associated with mental disorders. Stratified analysis by gender showed that male participants in the highest quartile of red meat intake had 92% higher risk of depression (95%CI: 1.17-3.15). Red and white meat intake was not associated with mental disorders in women. In overweight or obese individuals, no association was found between red meat intake and mental disorders, while higher intake of white meat was significantly associated with lower odds of psychological distress (OR=0.64; 95%CI: 0.42-0.99) and marginally associated with lower risk of depression (OR= 0.68; 95%CI: 0.45-1.00). In normal weight participants, highest quartile of red meat intake associated with increased odds of depression (OR= 1.66; 95%CI: 1.14-2.42). Conclusions We found that higher intake of red meat was associated with increased risk of depression, especially in males and normal weight participants. In overweight or obese subjects, white meat intake was inversely associated with psychological distress.
X-linked muscular dystrophy in a Labrador Retriever strain: phenotypic and molecular characterization.
Authors: Inès Barthélémy , Barthelemy Inès , Calmels Nadège , Weiss Robert B. , Tiret Laurent , Vulin Adeline , Wein Nicolas , Peccate Cécile , Drougard Carole , Beroud Christophe , Deburgrave Nathalie , Thibaud Jean-Laurent , Escriou Catherine , Punzon Isabel , Garcia Luis , Kaplan Jean-Claude , Flanigan Kevin M. , Leturcq France , Blot Stéphane
Published: March 2020

Background Canine models of Duchenne muscular dystrophy (DMD) are valuable to evaluate therapies because they faithfully reproduce the human disease. Several cases of dystrophinopathies have been described in canines, but the GRMD (Golden Retriever Muscular Dystrophy) model remains the one used in most preclinical studies. Methods We report a new spontaneous dystrophinopathy in a Labrador retriever strain, named LRMD (Labrador Retriever Muscular Dystrophy), for which a colony was established. Fourteen LRMD dogs were followed-up and compared to the GRMD standard. Results The clinical features of the GRMD disease were found in LRMD dogs, and the functional tests provided data roughly overlapping those measured in GRMD dogs, with similar inter-individual heterogeneity. Molecular techniques including RNA-sequencing allowed to map and identify the LRMD causal mutation, consisting in a 2.2-Mb inversion disrupting the DMD gene within its intron 20, and involving TMEM47 gene. In skeletal muscles, the Dp71 isoform was ectopically expressed as a probable consequence of the mutation. We found no evidence of polymorphism in the two LTBP4 and Jagged1 modifier genes that would explain the observed inter-individual variability. Conclusions This study provides a full comparative description of a new spontaneous canine dystrophinopathy, that we demonstrate is phenotypically equivalent to the GRMD model. We report a novel large DNA mutation within the DMD gene and provide evidence that LRMD is a relevant model to pinpoint additional DMD modifier genes.
Quantitative Proteomics Reveals the Regulatory Networks of Circular RNA BTBD7_hsa_circ_000563 in human coronary artery
Authors: Chen Jia-Xin , Hua Lei , Zhao Chen-Hui , Jia Qiao-Wei , Zhang Jing , Yuan Jin-Xia , Zhang Yong-Jie , Jin Jian-Liang , Gu Mu-Feng , Mao Zhi-Yuan , Sun Hai-Jian , Wang Lian-Sheng , Ma Wen-Zhu , Jia Enzhi
Published: March 2020

Background: To investigate the association of BTBD7_hsa_circ_000563 expression in coronary artery segments with atherosclerotic stenosis, and to explore the proteome-wide identification of the BTBD7_hsa_circ_000563-regulated proteins in coronary artery Methods: The coronary artery samples were obtained from two autopsy cases. The epicardial coronary artery of every autopsy was divided into 10 segments, and coronary atherosclerosis grade and extent of the coronary artery segments were analysed by Haematoxylin and Eosin (H&E) staining. The BTBD7_hsa_circ_000563 expression of 8 segments from case 2 was quantified using RT-qPCR analysis. Results: The present study demonstrated that coronary artery segments with severe atherosclerotic stenosis showed extremely low expression of the BTBD7_hsa_circ_000563, compared with normal coronary artery segments. Furthermore, it was predicted that hsa-miR-155-5p, and hsa-miR-130a-3p are targets of the BTBD7_hsa_circ_000563. The results from the present study may laid an epigenetic foundation for studying the underlying mechanisms of the development and progression of coronary artery atherosclerosis. Conclusions: BTBD7_hsa_circ_000563 were involved in atherosclerotic changes in coronary artery segments of human being, and the verification study, mechanism study, and function study are necessary in order for CAD patients to benefit from the personalized medicine in the future.
Situationsanalyse in der medienpädagogischen Mediatisierungsforschung
Authors: Wolf Karsten D. , Wegmann Konstanze
Published: March 2020

Der Beitrag fragt nach den Konsequenzen der kommunikationswissenschaftlichen Mediatisierungstheorie für die medienpädagogische Theorieentwicklung und Forschung. Zentral dabei ist die Forderung, nicht mehr den Einfluss von Einzelmedien zu untersuchen, sondern vielmehr auf einer Meta-Ebene zu analysieren, wie sich unser kommunikatives Handeln und die sich daraus konstruierenden Handlungssituationen innerhalb einer zunehmend komplexeren Medienumgebung verändern. Als theoretische Basis und empirischer Analyseansatz wird dazu zunächst das Konzept der Kommunikativen Figurationen vorgestellt; im Anschluss wird die Situationsanalyse als geeignete Methode zur Rekonstruktion kommunikativer Figurationen vorgeschlagen und ihre Potenziale für die medienpädagogische Forschung anhand einer Beispielstudie zu den kommunikativen Figurationen des informellen Lernens verdeutlicht. Der Artikel soll so einen Beitrag zur medienpädagogischen Theorieentwicklung sowie zum medienpädagogischen Methoden-Diskurs leisten.
Möglichkeitsräume für bildende Begegnungen im Internet gestalten
Authors: Hölterhof Tobias
Published: March 2020

Soziale Netzwerke sind für die Medienpädagogik äusserst interessante Plattformen und Dienste im Internet, die Kontakte und Relationen von Nutzenden ermöglichen und abbilden. Neben der Analyse solcher Plattformen rückt ihre Gestaltung in den Fokus medienpädagogischer Forschung, wenn Online-Umgebungen zur Unterstützung pädagogischen Handelns eingesetzt werden. Doch wie können solche Plattformen als Bildungsumgebungen fruchtbar gestaltet werden? Was sind allgemeine Perspektiven für den Einsatz solcher Systeme? Der Beitrag entwickelt aus der von Otto F. Bollnow vorgelegten bildungs- und existenzphilosophischen Erörterung von Begegnungen eine Bildungsperspektive für Soziale Netzwerke. Diese Perspektive versteht Soziale Netzwerke als Möglichkeitsräume für Begegnungen: Sie strukturieren soziale Relationen und bieten Kommunikationswerkzeuge sowie Wahlmöglichkeiten. Doch hierfür müssen Soziale Netzwerke entsprechend gestaltet sein. Im Schnittfeld von Medienpädagogik und Webtechnologie stellt der Beitrag Ansätze für die prototypische Gestaltung solcher Plattformen aus einem modularen Content Management System vor. Er diskutiert Eigenheiten und Spezifika eines solchen Gestaltungsprozesses, welcher im Sinne dieser Bildungsperspektive das Aufspannen eines sozialen Möglichkeitsraumes fokussiert um Soziale Netzwerke zu Orten der Begegnung werden zu lassen.
Control of the tomato leaf miner, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) larvae in laboratory using entomopathogenic nematodes from subtropical environment
Authors: Dlamini Bonginkhosi E. , Dlamini Nelisiwe , Masarirambi Michael T. , A. Nxumalo Kwanele
Published: March 2020

Tomato (Solanum esculentum) is one of the vegetable crops grown by both smallholder and commercial farmers in the Kingdom of Eswatini. Tomato leaf miner, Tuta absoluta M. is a major insect pest of tomatoes resulting in reduced tomato yields throughout the country. The study investigated the virulence of two sub-tropical EPN species on T. absoluta larvae. Steinernema yirgalemense and S. jeffreyense at different concentrations (0, 20, 40, 60 IJs/insect) were screened for efficacy (i.e. mortality rate) against larvae of T. absoluta in laboratory bioassays. Results obtained showed that S. yirgalemense and S. jeffreyense were able to kill T. absoluta larvae without significant differences between the two EPN species in 24-well bioassay trays. Significantly higher (p < 0.05) mortality was observed when 60 IJs/insect was used. The combination of S. yirgalemense at 60 IJs/insect (100%) and S. jeffreyense at 60 IJs/insect (98.3%) resulted in significantly higher (p < 0.05) mortality, compared with the other four combinations of EPN and concentration tested. In the leaf bioassays, S. yirgalemense (58.8%) resulted in significantly higher (p < 0.05) mean mortality compared to S. jeffreyense (46.4%). Steinernema yirgalemense at 60 IJs/insect resulted in significantly higher mean mortality compared to the other EPN and concentration combinations in the leaf bioassay. The results indicated that both EPNs tested were effective against T. absoluta larvae. Steinernema yirgalemense at 60 IJs/insect can effectively find T. absoluta larvae inside leaf mines, but large-scale field trials are recommended to demonstrate the potential use of the biocontrol agent within integrated pest management programs.
Thrombotic complications in patients with congenital heart defects after cardiac surgery
Authors: Gandaeva L. A. , Basargina E. N. , Zubkova K. Z. , Gordeeva O. B. , Derevnina Yu. V. , Zharova O. P. , Zhurkova N. V. , Sdvigova N. A. , Tepaev R. F. , Lastovka V. A.
Published: March 2020

The thrombotic complications develop in 3,6–13% of children with congenital heart defects in the postoperative period, which makes the diagnosis and prevention of thrombosis relevant. Permanent risk factors include the carriage of mutations/polymorphic variants of genes, leading to an imbalance in the procoagulant and anticoagulant hemostatic systems. In some cases, children after cardiac surgery are prescribed anticoagulants, warfarin is the most commonly used vitamin K antagonist, which can cause warfarin-associated skin necrosis as a result of vascular microthrombosis of the microvasculature. We provide our own observation – a case of thrombosis and warfarin-associated skin necrosis in a child after a multi-stage correction of congenital heart defect on the background of indirect anticoagulant therapy.
«Acute skin failure», unreasonably lost term
Authors: Azovskiy D. K. , Lekmanov A. U. , Pilyutik S. F.
Published: March 2020

Objective: to present data and analyze current data on diagnostics of acute skin failure in children. The term “acute skin failure” is rarely used in the literature. Among the works published in Russian, we found only one study of our colleagues from the Republic of Belarus, where we met the definition and description of this term. When searching the Pubmed database, we found 58 scientific works, only 7 of them were devoted to children. When determining the presence or absence of multiple organ failure syndrome, none of the scales used for adults and children included skin disorders. The majority of scales described changes in the respiratory system, kidneys, liver, cardiovascular system, neurological status and blood system. However, acute skin failure is a serious problem similar to insufficiency of internal organs. The clinical case demonstrates the possibility of effective intensive care in a child with acute skin failure. We believe that the diagnosis of acute skin failure as a primary or secondary component of multiple organ failure syndrome in children in the intensive care unit is an important step towards the correct and adequate treatment of such patients.
Information-analytical assessment systems for perinatal outcomes and children’s health status born by assisted reproductive technologies
Authors: Kovtun O. P. , Plaxina A. N. , Makutina V. A. , Ankudinov N. O. , Zilber N. A. , Limanovskay O. V. , Sinotova S. L.
Published: March 2020

Purpose: To integrate clinical databases based on the information and analytical systems of medical organizations (MO) and to evaluate outcomes and health of children born by assisted reproductive technologies (ART).

Research methods: To form database by integrating information and analytical systems of the medical organizations. To search and unify the data by means of freeware relational database management system (DBMS) – MySQL.

Results. A prototype application for the management and support of a unified clinical database to analyze and evaluate the outcomes of ART. To compare information from individual databases of MO one need to match fields in the form of unique personal records, field validation, processing of missing data. Significant (p <0.001) differences in gestational age and anthropometric data in the databases of medical organizations (76% of full-term children from the Automated System “Regional obstetric monitoring” (AS ROM) database compared with 18% according to the IS “Register of Children requiring Early Care”) were determined by the introduction of the conception of ART, along with the presence of perinatal risk factors in children. The created software can be used to create registers of medical organizations, as well as to support clinical decision-making in forecasting, modeling outcomes and children’s health after ART, developing personalized treatment and rehabilitation programs.

Conclusion. It is necessary to develop and implement information systems, to create ART registers on the basis of regional and national registers, to analyze the outcomes of the use of reproduction methods.
The state of the digestive system in children with systemic connective tissue diseases
Authors: Chyzhevskaya I. D. , Belyaeva L. M.
Published: March 2020

Purpose. To study the prevalence of the digestive system pathology in children with systemic connective tissue diseases.

Characteristics of children and research methods. We carried out a clinical and instrumental examination of 108 children with systemic connective tissue diseases hospitalized in the rheumatology department of the 4th City Children’s Clinical Hospital in Minsk from 2008 to 2015. 60 patients suffered from juvenile idiopathic arthritis (mean age 12.3 [9.4; 15.6] years), 23 children suffered from juvenile scleroderma (mean age 11.8 [9.7; 14.9] years) and 25 children suffered from systemic lupus erythematosus (mean age 13.1 [12.2; 16.3] years). All patients received long-term immunosuppressive and anti-inflammatory therapy.

Results. 75.9% patients had gastroenterological complaints, such as abdominal pains, nausea, heartburn. 69.4% of patients had endoscopic changes in the esophagus, stomach, and/or duodenum. According to the results of the morphological study, 43.5% of patients with systemic connective tissue diseases had mild inflammatory process, 29.6% of patients had average inflammatory process, and 3.7% of patients had severe inflammatory process. Among the children examined, 33 (55%) patients with juvenile idiopathic arthritis, 12 (48%) children with systemic lupus erythematosus and 11 (47.8%) patients with juvenile scleroderma were infected with Helicobacter pylori. Pathological changes of the hepatobiliary system and pancreas were diagnosed in 83.3% of children with systemic connective tissue diseases.

Conclusion. The revealed changes indicate a probable connection between the pathology of the digestive organs in children with systemic connective tissue diseases and substantiate the gastroenterological examination of this category of patients.
Clinical and epidemiological characteristics of measles in the Astrakhan region in 2013–2019
Authors: Kharchenko G. A. , Kimirilova O. G,
Published: March 2020

In the first quarter of 2019, we registered 872 cases of measles in Russia, indicating a tense epidemic situation of this disease.

Purpose.To determine clinical and epidemiological features of measles in the Astrakhan region (AR) from January 2013 to April 2019.

Material and methods.We analyzed 663 cases of measles confirmed by enzyme immunoassay (293 children + 370 adults) in the AR from January 2013 to April 2019.

Results.We found that in the age structure of measles incidence in AO prevail patients aged from 18 to 29 years old, unvaccinated or lacking vaccination information, unvaccinated children of 1-2 years old and children under 1 year old, not subject to measles vaccination. The main reasons for the lack of vaccination in children with measles under 17 years are medical withdrawal; and among adults – insufficient vaccination of people under 35 years and the absence of vaccination in people over 35 years. The main reasons for the incidence of measles among vaccinated children and adults is the violations of vaccination, inaccuracy of official measles vaccination data, which is confirmed by serological monitoring, indicating a decrease in the seropositive individuals among vaccinated persons. The presence of measles foci and the spread of infection can be explained by nosocomial outbreaks, spread of measles in the organized groups as a result of untimely identification and isolation of patients. Measles in children and adults of different age groups, both vaccinated and unvaccinated, occurred typically with a predominance of moderate form. The Filatov – Koplik symptom, despite its detection in only 54% of patients, remains the main sign for the diagnosis of measles in the catarrhal period of the disease, and pigmentation is a sign of the past illness.
Optimization of microalgae harvesting by sedimentation induced by high pH
Authors: Leite Luan de Souza , Daniel Luiz Antonio
Published: March 2020

Microalgae harvesting is a major hurdle for the production of high-value microalgal bioproducts on a large scale. Among harvesting techniques, pH-induced sedimentation stands out as an inexpensive and technically viable method. Nevertheless, there is little information available on the application of this method for microalgae cultivated in wastewater. In this context, the present study investigated the optimization of sedimentation parameters for Chlorella sorokiniana harvesting from wastewater. Parameter optimization was statistically determined by the response surface methodology. The optimal values included a velocity gradient of 250 s−1, mixing time of 10 seconds, and pH of 12, which enabled microalgae harvesting efficiencies of more than 97.8%. These optimal parameters also showed resilience through the physico-chemical variation of the photobioreactor effluent. Furthermore, wastewater quality improved significantly after microalgae harvesting. High removal was found for turbidity (97.9–98.3%), apparent color (92.2–97.2%), total Kjeldhal nitrogen (91.0–94.4%), and total phosphorus (92.8–98.6%). Centrifugation, as the dewatering method, and its operational parameters were also evaluated. Sedimentation followed by centrifugation increased the initial microalgae concentration by about 123 times. This study shows the importance of operational optimization and the results can be used as practical guidelines for microalgae harvesting on a large scale.
EVALUATION OF THE EFFECTIVENESS OF THE MENTORING PROGRAM USING THE MODEL OF D. KIRKPATRICK
Authors: Uvarov Mikhail Sergeevich
Published: March 2020

This article considers the evaluation of the effectiveness of the mentoring program using the model of D. Kirkpatrick from the point of view of sociology, discusses the feasibility of using the model of D. Kirkpatrick, explained the author's position on this issue.
The Role of Ubiquitin E3 Ligase in Atherosclerosis
Authors: Zhou Zhi-Xiang , Ren Zhong , Yan Bin-Jie , Qu Shun-Lin , Tang Zhi-Han , Wei Dang-Heng , Liu Lu-Shan , Fu Min-Gui , Jiang Zhi-Sheng
Published: March 2020

Atherosclerosis is a chronic inflammatory vascular disease. Atherosclerotic cardiovascular
disease is the main cause of death in both developed and developing countries. Many
pathophysiological factors, including abnormal cholesterol metabolism, vascular inflammatory
response, endothelial dysfunction and vascular smooth muscle cell proliferation and
apoptosis, contribute to the development of atherosclerosis and the molecular mechanisms
underlying the development of atherosclerosis are not fully understood. Ubiquitination is a
multistep post-translational protein modification that participates in many important cellular
processes. Emerging evidence suggests that ubiquitination plays important roles in the pathogenesis
of atherosclerosis in many ways, including regulation of vascular inflammation, endothelial
cell and vascular smooth muscle cell function, lipid metabolism and atherosclerotic
plaque stability. This review summarizes important contributions of various E3 ligases to the
development of atherosclerosis. Targeting ubiquitin E3 ligases may provide a novel strategy
for the prevention of the progression of atherosclerosis.
QUANDO O ASSUNTO É SOBRE RELIGIÕES DE MATRIZ AFRICANA: LEI 10.639∕2003
Authors: Santos Conceição Joanice
Published: March 2020

O presente artigo objetiva refletir sobre a aplicação da Lei 10.639∕2003, em especial, sobre os aspectos das religiões de matriz africana, tendo em vista que a lei sancionada tornou obrigatório o ensino da história e da cultura africana e afro-brasileira em todas as unidades escolares do País. Entendemos que falar sobre racismo não é tarefa fácil, principalmente no ambiente escolar, que, embora possibilite a construção de conhecimento, cultiva a manutenção de preconceitos e estereótipos em relação a determinados grupos, em especial, negros e indígenas. Esse preconceito é acentuado quando se coloca em relevo as religiões de matriz africana, frente ao crescimento de denominações pentecostais e neopentecostais que têm praticado diversos desrespeitos religiosos por todo o Brasil. Idealmente, a escola brasileira deve fornecer informações históricas relativas às matrizes que deram origem ao País; entretanto, há uma maior valorização do pensamento e culturas eurocêntricas, descuidando-se abundantemente das diversidades culturais, econômicas e tecnológicas do continente africano. O método utilizado é o qualitativo, baseando-se na pesquisa documental e no contato com os professores, revelando assim que a não aplicação da Lei 10.639∕2003 resulta de um conjunto de ações e comportamentos, com destaque para o racismo. A partir disso apresento o texto.
RE/DES/CONSTRUINDO IN/DIFERENÇAS: A EXPULSÃO COMPULSÓRIA DE ESTUDANTES TRANS DO SISTEMA ESCOLAR
Authors: Batista de Oliveira Junior Isaias , Rose Maio Eliane
Published: March 2020

Estudantes Trans(E.T.) – Travestis, Transexuais e Transgêneros – são vítimas do processo de heteronormatização ao arquitetarem seus corpos em conformidade com sua identidade de gênero. A escola, agente dessa colonização, acaba por afastar do seu interior E.T. por meio da expulsão compulsória, invisibilizada sob o manto do fracasso escolar. Buscando subsidiar estes apontamentos, assumimos como objetivo central descrever a construção da identidade de E.T. e como a cultura da diferença é re/produzida no contexto escolar apresentando recortes de uma pesquisa realizada com educadores(as) para a obtenção do título de mestre, sustentada na teoria dos Estudos Culturais. Os dados obtidos apontaram que as fobias das quais alunos(as) homossexuais são vítimas assumem fórum de agravamento quando destinadas a E.T. Essa transfobia consiste na estigmatização e retirada de direitos básicos, como o reconhecimento do nome social, livre acesso a espaços no interior da escola e uso de sanitários ao gênero que se identifica. Concluímos que a adoção de estratégias que discutam a identidade de gênero, violência de gênero, transfobia, manifestações das sexualidades, dentre outros, devem fazer parte do cotidiano escolar de forma a envolver todos os seus agentes no combate à violência imputada a E.T., promovendo a cultura do respeito para com as diferenças.
Using the Technology Acceptance Model to Explore Adolescents’ Perspectives on Combining Technologies for Physical Activity Promotion Within an Intervention: Usability Study
Authors: Drehlich Mark , Naraine Michael , Rowe Katie , Lai Samuel K , Salmon Jo , Brown Helen , Koorts Harriet , Macfarlane Susie , Ridgers Nicola D
Published: March 2020

Background

Wearable activity trackers and social media have been identified as having the potential to increase physical activity among adolescents, yet little is known about the perceived ease of use and perceived usefulness of the technology by adolescents.

Objective

The aim of this study was to use the technology acceptance model to explore adolescents’ acceptance of wearable activity trackers used in combination with social media within a physical activity intervention.

Methods

The Raising Awareness of Physical Activity study was a 12-week physical activity intervention that combined a wearable activity tracker (Fitbit Flex) with supporting digital materials that were delivered using social media (Facebook). A total of 124 adolescents aged 13 to 14 years randomized to the intervention group (9 schools) participated in focus groups immediately post intervention. Focus groups explored adolescents’ perspectives of the intervention and were analyzed using pen profiles using a coding framework based on the technology acceptance model.

Results

Adolescents reported that Fitbit Flex was useful as it motivated them to be active and provided feedback about their physical activity levels. However, adolescents typically reported that Fitbit Flex required effort to use, which negatively impacted on their perceived ease of use. Similarly, Facebook was considered to be a useful platform for delivering intervention content. However, adolescents generally noted preferences for using alternative social media websites, which may have impacted on negative perceptions concerning Facebook’s ease of use. Perceptions of technological risks included damage to or loss of the device, integrity of data, and challenges with both Fitbit and Facebook being compatible with daily life.

Conclusions

Wearable activity trackers and social media have the potential to impact adolescents’ physical activity levels. The findings from this study suggest that although the adolescents recognized the potential usefulness of the wearable activity trackers and the social media platform, the effort required to use these technologies, as well as the issues concerning risks and compatibility, may have influenced overall engagement and technology acceptance. As wearable activity trackers and social media platforms can change rapidly, future research is needed to examine the factors that may influence the acceptance of specific forms of technology by using the technology acceptance model.

Trial Registration

Australian and New Zealand Clinical Trials Registry ACTRN12616000899448; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=370716
KAJIAN PROSEDUR PEMINDAHAN ARSIP: STUDI KASUS DI BANK INDONESIA
Authors: Susiani Fitri
Published: March 2020

This paper describes the procedure for transferring records carried out by Bank Indonesia. Transfer of records is one part of the shrinking program archive. Transfer of records is important to do to protect records that have a use value and to avoid stacking records. The data used in the study are primary data and secondary data. Primary data were obtained from observations or participatory observations, in-depth interviews with records managers, as well as studies of archival policies issued by Bank Indonesia. The secondary data in the form of an assessment of library materials. The conclusion obtained from this paper is the transfer of records at Bank Indonesia using two methods, namely conventional methods and application-based methods. Guidelines for moving records have also been referring to international standards, namely ISO 15489-2016. The facilities and infrastructure used in the transfer of records are also in accordance with archival standards with adequate capacity. In carrying out the activities of the shrinking of the archive was not found significant obstacles.
KAJIAN PENGELOLAAN PERSONNEL FILES BERBASIS ELEKTRONIK: STUDI KASUS KANTOR REGIONAL II BADAN KEPEGAWAIAN NASIONAL (BKN) SURABAYA
Authors: Napsi Failina Zuhrotun
Published: March 2020

This paper examines the procedures for managing electronic files based personnel. The research locus is in Regional Office II of the National Personnel Agency (BKN) Surabaya. Human resource management organizations create personnel files or personnel files that are managed in a certain way in accordance with the vision and mission. Basically, personnel files created by the State Personnel Agency are a vital type of archive. The data used consists of primary data and secondary data. Data collection methods used in this study are observation, interviews, and literature study. Observations or observations made at the Regional Office II of the National Personnel Agency (BKN) Surabaya. The interview aims to add information through the staffing administration. Literature study is used to collect data in order to strengthen the exposure that has been described by the author. Management of personnel files at Regional Office II of the Surabaya National Personnel Agency (BKN) based on the storage media is done physically and electronically. Electronically, the management of personnel files is carried out starting from scanning or scanning, storing and maintaining.
Francisco Villa en la prensa carrancista (1914-1915). La construcción del adversario
Authors: Méndez Lara Francisco Iván
Published: March 2020

La imagen de Francisco Villa, uno de los revolucionarios mexicanos más conocidos en el mundo, ha vivido diversas transformaciones en el transcurso del tiempo. Ello se debe a la gran variedad de versiones que existen acerca de su vida, particularmente sobre su pasado de “bandido”, las cuales propiciaron el surgimiento de diversas leyendas que él mismo celebró y difundió en muchas ocasiones. Las fotografías, el cine, la historia oral, pero particularmente la prensa, construyeron la imagen de Pancho Villa. Este artículo explica cómo y por qué se construyó la representación del divisionario duranguense en la prensa carrancista publicada en México –opositora a su proyecto revolucionario– durante la lucha de facciones, de finales de 1914 a mediados de 1915; dicho de otra forma, desde la ruptura revolucionaria hasta el triunfo carrancista en las batallas del Bajío.
La Editorial del Centro de Cultura Digital: de la experimentación en práctica a la creación de nuevos públicos
Authors: Ortega Élika
Published: March 2020

Este artículo explora la historia y la producción del proyecto Editorial del Centro de Cultura Digital de México. Fundado en 2014, Editorial se ha convertido en un nodo de creación y discusión sobre la producción cultural digital en México y el mundo hispano. Las características de Editorial –que oscilan entre sus funciones como organismo gubernamental bajo los auspicios de la Secretaría de Cultura y su perfil de editorial independiente– han permitido a su directora Mónica Nepote, en conjunto con un gran número de colaboradores, construir un público no experto para las temáticas de la cultura digital, llevar a cabo una labor educativa y alfabetizadora, al tiempo que, de forma paralela, ha logrado convertirse en un centro tanto de experimentación e innovación de las prácticas editoriales como sobre la interrogación del rol del libro y otros objetos bibliográficos en el siglo XXI.
La crisis del campo editorial mexicano y el imaginario de sus trabajadores
Authors: Kloss Fernández del Castillo Gerardo
Published: March 2020

Reflexiones sobre los trabajadores del campo editorial mexicano y algunos de sus problemas, como las múltiples funciones del editor, los nuevos actores en el proceso, la precariedad laboral, la crisis actual y sus posibles proyecciones a futuro. La diversidad de las formas de producción y el consumo de los textos están en pleno reacomodo, debido a los novedosos soportes digitales, la fluidez y fragmentación de los contenidos y los nuevos modos de construir la percepción de la realidad en las redes sociales. Pero el imaginario de los trabajadores editoriales cultiva con cariño tantas idealizaciones que no les permite ver sus propias contradicciones y les resulta difícil abordar conscientemente las nuevas oportunidades, por lo cual prefieren verlas como amenazas a las que es preciso resistir.
Towards Statement Identity
Authors: Ginsberg Mitchell
Published: March 2020

Abstract
A Correct Account of Essentialism?
Authors: Tomberlin James E.
Published: March 2020

Abstract
Teoría de la verdad en Tarski
Authors: Nuño Juan A.
Published: March 2020

Resumen
Lógica y razón
Authors: Ferrater Mora José
Published: March 2020

Resumen
Mr. Walker on the Self
Authors: Rohatyn Dennis
Published: March 2020

Abstract
Eduardo García Máynez, Filosofía del derecho
Authors: Esquivel Javier
Published: March 2020

Resumen
El argumento del lenguaje privado (I)
Authors: Villanueva Enrique
Published: March 2020

Resumen
La paradoja de la adición: respuesta al maestro Margáin
Authors: Bunge Mario
Published: March 2020

Resumen
Eike von Savigny, Analytische Philosophie
Authors: Esquivel Javier
Published: March 2020

Resumen
Reasons
Authors: Harman Gilbert
Published: March 2020

Abstract
El Tractatus desenmascarado (Réplica a Margáin)
Authors: Villoro Luis
Published: March 2020

Resumen
J.N. Crossley et al., What Is Mathematical Logic?
Authors: Robles José Antonio
Published: March 2020

Resumen
The Simplicity Argument in Wittgenstein and Russell
Authors: Mijuskovic Ben
Published: March 2020

Abstract
Comments on "Individuation and Non-Identity": A Reply to Héctor-Neri Castañeda
Authors: Loux Michael
Published: March 2020

Abstract
Filósofos "modernos" de la ciencia
Authors: Gómez Ricardo
Published: March 2020

Resumen
Epistemología, psicología y cambio científico
Authors: Nudler Oscar
Published: March 2020

Resumen
Plato, Phaedo
Authors: Schmidt Osmanczik Ute
Published: March 2020

Resumen
El problema de los universales en Gottlob Frege
Authors: Beuchot Mauricio
Published: March 2020

Resumen
Cualidades (simples) y semejanza
Authors: Robles J.A.
Published: March 2020

Resumen
Joseph Horovitz, Law and Logic
Authors: Esquivel Javier
Published: March 2020

Resumen
The Justification of Equality
Authors: Nagel Thomas
Published: March 2020

Abstract