bluuebunny/crossref_metadata_2025 huggingface dataset:
Nanotechnological Advances in the Treatment of Epilepsy
Authors: Ansari Mohammed Tahir , Ali Ola Asem Mahmoud Abdou , Shaikh Mohd. Farooq , Hasnain M Saquib , Sami Farheen , Khan Abdullah
Published: December 2021

:

Epilepsy is known as one of the major challenges for medical science. The sudden appearance
of a seizure has been a significant health emergency as it may lead to further complications.
Although key advancements have been achieved in terms of pharmacological approaches for
epilepsy, many issues remain uncertain. Lipid carriers have been at the forefront, especially in neurodegenerative
diseases, such as epilepsy, Alzheimer’s, dementia, etc. The blood-brain barrier still
appears to be a major impediment in the successful treatment of epileptic seizures. This is mainly
due to the limited bioavailability of most anti-convulsant drugs. The present review encompasses
the issues underlying the current approach for epilepsy drug treatment and highlights the newer,
novel, and more precise drug delivery system to manage seizures. The advantage of using a lipidbased
delivery system is its superior absorption in the brain cells. Ample evidence shows that reducing
the particle size also infuses the drug easily through the blood-brain barrier. The application of
liposomes, polymeric nanoparticles, metallic nanoparticles, and solid lipid nanoparticles for the
treatment and management of epilepsy has been highlighted in the present review. This review provides
an overview of the current status of the treatment and recent advances in the treatment of
epilepsy.
Serum Alkaline Phosphatase and Calcium in Relation to Periodontal Status among Perimenopausal and Postmenopausal Women
Authors: Hutomo Dimas I. , Masulili Sri Lelyati C. , Tadjoedin Fatimah M. , Kusdhany Lindawati S.
Published: December 2021

Background:

Menopause is a physiological phenomenon that occurs in aging women. Periodontal disease is associated with menopausal status. Alkaline phosphatase (ALP) plays a role in general and periodontal bone turnover. Calcium is essential for the maintenance of bone and teeth, and serum ALP and calcium are specific bone markers related to the acceleration of bone mass loss in elderly women and periodontitis.

Objectives:

The aim of this study was to correlate the levels of serum ALP and calcium with periodontal status in perimenopausal and postmenopausal women with periodontitis.

Methods:

A total of 22 perimenopausal and 49 postmenopausal women underwent a full periodontal examination assessing the pocket depth, number of teeth lost, clinical attachment loss, plaque index, calculus index, and papillary bleeding index. Using these measurements, the subjects were divided according to periodontal severity. Serum ALP and calcium were measured using the Enzyme-Linked Immunosorbent Assay (ELISA) method. A correlation between serum ALP and calcium to periodontal status was investigated.

Results:

Serum ALP was significantly correlated with the severity of periodontitis, clinical attachment loss, and the number of teeth lost among perimenopausal and postmenopausal women (p < 0.05). Serum calcium levels were not correlated with periodontal status.

Conclusion:

Postmenopausal women tended to have more periodontal breakdown, and the level of serum ALP was increased in severe periodontitis.
Vitamin D Regulates the Expression of Immune and Stress Response Genes in Dengue Virus-infected Macrophages by Inducing Specific MicroRNAs
Authors: Fernandez Geysson Javier , Castillo Jorge Andrés , Giraldo Diana Marcela , Urcuqui-Inchima Silvio
Published: December 2021

Background:

The pathogenesis associated with Dengue virus (DENV) infection is marked by the impairment of host immune response. Consequently, the modulation of immune response has emerged as an important therapeutic target for the control of DENV infection. Vitamin D has been shown to regulate the immune response in DENV infection, although the molecular mechanism remains poorly understood. Post-transcriptional regulation of mRNA by miRNAs offers an opportunity to gain insight into the immunomodulation mediated by vitamin D

Objective:

Previously, it has been observed that a high dose of vitamin D (4000 IU) decreased DENV-2 infection and inflammatory response in monocyte-derived macrophages (MDMs). Here, we examine whether high or low doses of vitamin D supplements exert differential effect on miRNA expression in DENV-infected macrophages

Methods:

We analyzed miRNA expression profiles in MDMs isolated from healthy individuals who were given either 1000 or 4000 IU/day of vitamin D for 10 days. MDMs before or after vitamin D supplementation were challenged with DENV-2, and miRNAs profiles were analyzed by qPCR arrays.

Results:

DENV-2 infected MDMs supplemented with 4000 IU, showed up-regulation of miR-374a-5p, miR-363-3p, miR-101-3p, miR-9-5p, miR-34a-5p, miR-200a-3p, and the family of miRNAs miR-21-5p, and miR-590-p. The miRNA profile and predicted target mRNAs suggested regulatory pathways in MDMs obtained from healthy donors who received higher doses of vitamin D. These DENV-2 infected MDMs expressed a unique set of miRNAs that target immune and cellular stress response genes.

Conclusion:

The results suggest vitamin D dose-dependent differential expression of miRNAs target key signaling pathways of the pathogenesis of dengue disease.
The Impact of Microplastic on Human Health
Authors: Almeida Amanda Souza Reis , de Souza Cleide Barbieri
Published: December 2021

Background:

Microplastics are considered an emerging contaminant due to their wide
distribution and production in the environment, representing constant exposure to humans. However,
little is known about the effects it can trigger in the body.

Objective:

The objective of this study is to establish a concrete relationship between microplastics
and the human body, their means of production, exposure, systemic responses, and diseases caused
by their presence.

Methods:

In this context, a review article of foreign and national literature was developed through
the PubMed and Scielo Indexers, where studies were found that address the production of plastic,
the paths that lead to the production of microplastics, and the exposure and damage that it represents
to human health, being possible to exclude the literary sums with a publication date before
2017.

Results:

They showed that translocation of the residues occurs to the circulatory and lymphatic system
via the respiratory and gastrointestinal tracts. Once in the body, microplastic can stimulate a
chronic inflammatory response that functions as a precursor to neoplasia and fibrosis, or carry toxic
compounds such as heavy metals, endogenous disruptors, biofilms, and persistent organic pollutants.
In addition, lung biopsies have shown plastic fibers in patients with respiratory diseases, highlighting
a potentially dangerous accumulation.

Conclusion:

The present moment demonstrates that experimental research to prove the effect of microplastics
is extremely necessary since the controversy among authors and the repetition of information
already affirmed that the research done so far is not sufficient.
Solution Tetrahydrobiopterin Radical vs. the Enzyme-Bound Radical: A
Paramagnetic Reconciliation
Authors: NejatyJahromy Yaser
Published: December 2021

Background:

Nitric oxide synthase (NOS) catalyzes the formation of nitric oxide (NO) and citrulline from L-arginine, dioxygen (O2), and nicotinamide adenine dinucleotide phosphate (NADPH) in a two-step reaction, with the enzyme-bound intermediate Nω-hydroxy-L-arginine (NHA). Previous electron paramagnetic resonance (EPR) studies of NOS reaction have shown that (6R, 1'R, 2'S)-6-(l',2'-dihydroxypropyl)-5,6,7,8-tetrahydropterin (H4B) acts as a single electron donor in both steps of the reaction, resulting in the transient generation of a tetrahydropterin cation radical (H4B•+).

Results:

H4B•+can also be chemically generated in strongly acidic solutions. EPR studies of chemically generated H4B•+and similar pterin radicals date back to the 1960s. However, the reported paramagnetic parameters of H4B•+in NOS do not seem to match the corresponding reported parameters for either H4B•+or other pterin centered radicals chemically generated in solution. In particular, the rather isotropic hyperfine coupling of ca. 45 MHz for 1H6 of H4B•+in NOS is at least 15 MHz larger than that of H4B•+ or any other previously studies pterin solution radical. In the work reported here, a combination of 9.5 - 9.8 GHz contentious wave (cw-) EPR, 34GHz 1H electron nuclear double resonance (ENDOR), spectral simulation and Density Functional Theory (DFT) calculations were used to investigate this seeming discrepancy.

Conclusion:

We demonstrated that the differences in the paramagnetic parameters of the chemically generated H4B radicals in solutions and those of the H4B radicals in NOS are consistent with the presence of two different conformers of the same cation radical in the two media.
Ekspor Sampah Uni Eropa ke Indonesia sebagai Bentuk Eco-Imperialism
Authors: Khairunnisa Meyfitha Dea
Published: December 2021

Environmental policy has become an important aspect in reviewing environmental issues in international relations. The European Union is a regional institution that has been very active in international environmental cooperation. However, at the same time the European Union is one of the largest waste exporters to countries in Asia, including Indonesia. Waste export is a free trade mechanism that allows developed countries to send waste to developing countries to be processed as industry materials. This then becomes contradictory to the commitment of the European Union in promoting environmentally friendly policies and policies for the export of waste are considered as a form of eco-imperialism. This article discusses how the waste export policy by the European Union has become a form of ecological colonization for Indonesia as a waste recipient. Keywords: waste export; eco-imperialism; environmental policy
Availability and Suitability of Digital Health Tools in Africa for Pandemic Control: Scoping Review and Cluster Analysis
Authors: Silenou Bernard C , Nyirenda John L Z , Zaghloul Ahmed , Lange Berit , Doerrbecker Juliane , Schenkel Karl , Krause Gérard
Published: December 2021

Background

Gaining oversight into the rapidly growing number of mobile health tools for surveillance or outbreak management in Africa has become a challenge.

Objective

The aim of this study is to map the functional portfolio of mobile health tools used for surveillance or outbreak management of communicable diseases in Africa.

Methods

We conducted a scoping review by combining data from a systematic review of the literature and a telephone survey of experts. We applied the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines by searching for articles published between January 2010 and December 2020. In addition, we used the respondent-driven sampling method and conducted a telephone survey from October 2019 to February 2020 among representatives from national public health institutes from all African countries. We combined the findings and used a hierarchical clustering method to group the tools based on their functionalities (attributes).

Results

We identified 30 tools from 1914 publications and 45 responses from 52% (28/54) of African countries. Approximately 13% of the tools (4/30; Surveillance Outbreak Response Management and Analysis System, Go.Data, CommCare, and District Health Information Software 2) covered 93% (14/15) of the identified attributes. Of the 30 tools, 17 (59%) tools managed health event data, 20 (67%) managed case-based data, and 28 (97%) offered a dashboard. Clustering identified 2 exceptional attributes for outbreak management, namely contact follow-up (offered by 8/30, 27%, of the tools) and transmission network visualization (offered by Surveillance Outbreak Response Management and Analysis System and Go.Data).

Conclusions

There is a large range of tools in use; however, most of them do not offer a comprehensive set of attributes, resulting in the need for public health workers having to use multiple tools in parallel. Only 13% (4/30) of the tools cover most of the attributes, including those most relevant for response to the COVID-19 pandemic, such as laboratory interface, contact follow-up, and transmission network visualization.
Measuring and Improving Evidence-Based Patient Care Using a Web-Based Gamified Approach in Primary Care (QualityIQ): Randomized Controlled Trial (Preprint)
Authors: Burgon Trever , Casebeer Linda , Aasen Holly , Valdenor Czarlota , Tamondong-Lachica Diana , de Belen Enrico , Paculdo David , Peabody John
Published: December 2021

BACKGROUND

Unwarranted variability in clinical practice is a challenging problem in practice today, leading to poor outcomes for patients and low-value care for providers, payers, and patients.

OBJECTIVE

In this study, we introduced a novel tool, QualityIQ, and determined the extent to which it helps primary care physicians to align care decisions with the latest best practices included in the Merit-Based Incentive Payment System (MIPS).

METHODS

We developed the fully automated QualityIQ patient simulation platform with real-time evidence-based feedback and gamified peer benchmarking. Each case included workup, diagnosis, and management questions with explicit evidence-based scoring criteria. We recruited practicing primary care physicians across the United States into the study via the web and conducted a cross-sectional study of clinical decisions among a national sample of primary care physicians, randomized to continuing medical education (CME) and non-CME study arms. Physicians “cared” for 8 weekly cases that covered typical primary care scenarios. We measured participation rates, changes in quality scores (including MIPS scores), self-reported practice change, and physician satisfaction with the tool. The primary outcomes for this study were evidence-based care scores within each case, adherence to MIPS measures, and variation in clinical decision-making among the primary care providers caring for the same patient.

RESULTS

We found strong, scalable engagement with the tool, with 75% of participants (61 non-CME and 59 CME) completing at least 6 of 8 total cases. We saw significant improvement in evidence-based clinical decisions across multiple conditions, such as diabetes (+8.3%, P<.001) and osteoarthritis (+7.6%, P=.003) and with MIPS-related quality measures, such as diabetes eye examinations (+22%, P<.001), depression screening (+11%, P<.001), and asthma medications (+33%, P<.001). Although the CME availability did not increase enrollment in the study, participants who were offered CME credits were more likely to complete at least 6 of the 8 cases.

CONCLUSIONS

Although CME availability did not prove to be important, the short, clinically detailed case simulations with real-time feedback and gamified peer benchmarking did lead to significant improvements in evidence-based care decisions among all practicing physicians.

CLINICALTRIAL

ClinicalTrials.gov NCT03800901; https://clinicaltrials.gov/ct2/show/NCT03800901
Ortiz Nicolás, J. C. y Alatorre Gúzman, D. (Comps.). (2019). Innovación Social y Diseño. UNAM. ISBN: 9786073025683
Authors: Hernández Palomino Ana Elena
Published: December 2021

Se describen y analizan las principales aportaciones del libro Innovación Social y Diseño, una obra compilada por dos académicos mexicanos: Dr. Juan Carlos Ortiz Nicolás y Mtro. Diego Alatorre. Se enfatiza en los objetivos didácticos y pedagógicos para la enseñanza y práctica del diseño de una obra que ayuda al lector a comprender la trayectoria de esta disciplina; una travesía donde el diseñador se convierte en un agente de cambio y se conduce hacia la praxis de la innovación social. En este libro, investigadores y académicos brindan aportes teóricos y describen procesos y alcances de la innovación social para el diseño, coincidiendo en que las bondades de este enfoque no solo recaen en el éxito del desarrollo de productos innovadores y/o el provecho de los negocios, sino que también pueden influir positivamente en la calidad de vida de las personas a través de la construcción de relaciones sistémicas que pueden ser socialmente beneficiosas.
Social Innovation Studies, un paso adelante en la construcción del campo de la innovación social
Authors: Cote Luz Andrea , Ricci Emilio
Published: December 2021

Los estudios teóricos y bibliométricos realizados sobre la innovación social (IS) indican con frecuencia que, pese al protagonismo que ha ganado en las estrategias de organismos multilaterales y en las estructuras gubernamentales y las políticas públicas de una diversidad de países, el campo adolece de claridad conceptual e investigativa. La falta de revistas especializadas y redes de coautoría habrían incidido en esta situación. A nivel internacional, el enfoque de la IS ha sido marcado principalmente por Europa y Norteamérica, regiones en las que la investigación y la publicación científica se han visto estimuladas por el ascenso del término en programas de desarrollo. No obstante, en Latinoamérica, la IS ha tenido sus propias características y merece un tratamiento con marcos conceptuales pertinentes. Social Innovation Studies (SIS) busca reunir la atomizada publicación latinoamericana en la materia y convocar a los autores de la región para entablar un diálogo internacional basado en un análisis de la realidad regional que aborde un amplio espectro, desde enfoques micro sustentados en análisis de casos, hasta enfoques macro que relacionen la IS con los grandes procesos de cambio social.
Innovative Study on Microstructural Change in Duplex Stainless Steel in Corrosive Media
Authors: Banerjee Sumit
Published: December 2021

Abstract: Duplex Stainless Steel was developed long back in 1930 and gradually finds its wide application because of its high strength, good weldability, good toughness and resistance to stress corrosion cracking. This alloy finds its application in pressure vessels, bridges, process plants and also in typically down to minus 50 degree centigrade applications. However, because of its high alloy content thermal conductivities of duplex stainless steel are low. Casting this alloy is difficult and can be industrially used after proper heat treatment. In this present study corrosion rates were measured for CD4MCu in terms of weight loss/unit area/hour and microstructures were observed in different corrosive medium with time as variable.
Comparative Study of Soil Samples and its Physico Chemical Parameter from Wadwani Tehsil
Authors: Shitre Dr. Praven V.
Published: December 2021

Abstract: India is one of the populated countries and Indian economy is highly depending on agriculture field. Indian farming is the main source of income for most of the population. So farmers are always curious about yield prediction. To increase yield production many factors are responsible like soil, weather, rain, fertilizers and pesticides. In the present study we are investigate the soil samples for its physico-chemical analysis in Wadwani Tehsil. The main purpose of present study is analyse the fertility level of the soil with the help of pH, EC, Organic Carbon, Nitrogen, Potassium, Phosphorous, Sulpher, Zinc etc. and recommend essential nutrients necessary in Wadwani Tehsil Marathwada region Maharashtra. Six representative samples were obtained and analysed for its pH, EC, Phosphorus, Potassium, and other important nutrient useful for agricultural. Keywords: Soil Properties, Nutrient Parameter, pH, EC, P, K, S, Zn, Mn, Beed.
Romper con la razón ilustrada: Una propuesta para generar empatía con los seres humanos de las naciones originarias
Authors: Mora Martínez Roberto
Published: December 2021

El presente escrito busca promover la empatía con la población de las naciones originarias, a través de exponer su pensamiento filosófico y sabiduría. Un punto de suma importancia, el cual se expone en este trabajo, es que su estructura original, esto es prehispánica, se ha perdido, por lo que las referencias citadas se sustentan en la manera como han sido reelaboradas en el presente.

De tal modo que, el conocimiento transmitido, el cual se caracteriza por considerar la unidad de intelecto y sentimientos, constituye una opción a la ya perimida noción de razón universal, objetiva y desinteresada, defendida en el pensamiento europeo.

Expongo un ejemplo sobre la manera como el contexto social influye en la percepción negativa de los indígenas, abordo, entre otros datos, la experiencia del boliviano Alcides Arguedas. Finalmente se combinan las propuestas de diversos especialistas como los indígenas Miguel Hernández y Carlos Huamán con los estudios de Luis Villoro, para sustentar una propuesta alternativa a la razón moderna.
Dolor perineal en relación con las tasas indiscriminadas de episiotomía
Authors: Dos Santos Gustavo Gonçalves
Published: December 2021

Sr. Editor, de acuerdo con el artículo: "Caracterización del dolor perineal postparto en puérperas"(1), vengo a través de esta Carta a difundir el conocimiento técnico y científico sobre las notas del manuscrito publicado en el año 2016 en la Revista Universidad y Salud. Además de ser Enfermero Obstetra y Profesor, confieso a la Junta Editorial, a los lectores y a los autores del manuscrito que todas las producciones científicas son extremadamente relevantes y significativas en el campo de la Educación y la Investigación. Por esta razón, utilizaré este medio para hacer mis anotaciones relacionadas con las prácticas profesionales y el uso indiscriminado de la episiotomía, especialmente en Brasil.
Ejercicio y educación mejoran equilibrio y la calidad de vida en mujeres con incontinencia urinaria de esfuerzo
Authors: Pérez-Cimma Nashari , Cigarroa Igor , Zapata-Lamana Rafael , Sepúlveda-Martin Sonia , Espinoza-Pulgar Pamela , Sarqui Carla
Published: December 2021

Introducción: La incontinencia urinaria por esfuerzo (IUE) tiene una alta prevalencia en mujeres adultas, afectando variables psicológicas, sociales y funcionales como la disminución de capacidad de equilibrio, debido a una escasa contribución en los movimientos del tronco hacia una corrección postural. Objetivo: Determinar los efectos de un programa basado en ejercicio muscular de piso pélvico y educación sobre el equilibrio estático y la calidad de vida en mujeres con IUE. Materiales y métodos: Participaron 18 mujeres con IUE durante 12 semanas en 10 sesiones de ejercicio muscular de piso pélvico y educación (hábitos de higiene, micción, ingesta de líquidos). Pre y post-intervención se evaluó equilibrio estático mediante oscilografía postural y calidad de vida mediante el International Consultation on Incontinence Questionnaire Short-Form (ICQ-SF). Los datos fueron analizados con la prueba no paramétrica de Wilcoxon. Resultados: Se encontró una disminución significativa en el área de desplazamiento del centro de presión en el subtest ojos abiertos (p=0,027) y en el subtest ojos cerrados (p=0,006). Disminuyó la sintomatología asociada a IUE (p=0,0001). Conclusiones: Pos-intervención mejora equilibrio estático y calidad de vida, confirmando los efectos positivos de este programa que pueden servir de orientación a profesionales de la salud que trabajan con mujeres con IUE.
Funcionalidad familiar, soporte de amigos y rendimiento académico en estudiantes de odontología
Authors: Tamayo-Cabeza Guillermo , Hernandez-Torres Arleth , Diaz-Cardenas Shyrley
Published: December 2021

Introducción: Los factores relacionados con la funcionalidad familiar en estudiantes universitarios podrían asociarse con la deserción académica e impactar de manera negativa sobre el rendimiento académico. Objetivo: Describir las relaciones entre las características sociodemográficas y familiares, con la funcionalidad familiar, el soporte de amigos y el rendimiento académico en los estudiantes de odontología de una universidad pública de la ciudad de Cartagena. Materiales y métodos: Estudio de corte transversal, con una muestra de 438 estudiantes. Se utilizó un instrumento tipo encuesta sobre variables sociodemográficas, características familiares y de la vivienda. Los datos fueron analizados a partir de estadística descriptiva y análisis bivariados con la prueba Chi cuadrado de Pearson. Resultados: Se observó una relación estadísticamente significativa entre la edad y la funcionalidad familiar (p=0,0029). Asimismo, se obtuvo una relación significativa entre la procedencia y el soporte de amigos (p=0,0230), así como entre la baja escolaridad y la funcionalidad familiar (p=0,0018). Conclusiones: La identificación de los factores que se relacionan con la funcionalidad familiar y el soporte de amigos pueden contribuir a determinar qué aspectos deben considerarse para el diseño e implementación de intervenciones académicas dirigidas a estudiantes del programa.
Graph Picture of Linear Quantum Networks and Entanglement
Authors: Chin Seungbeom , Kim Yong-Su , Lee Sangmin
Published: December 2021

The indistinguishability of quantum particles is widely used as a resource for the generation of entanglement. Linear quantum networks (LQNs), in which identical particles linearly evolve to arrive at multimode detectors, exploit the indistinguishability to generate various multipartite entangled states by the proper control of transformation operators. However, it is challenging to devise a suitable LQN that carries a specific entangled state or compute the possible entangled state in a given LQN as the particle and mode number increase. This research presents a mapping process of arbitrary LQNs to graphs, which provides a powerful tool for analyzing and designing LQNs to generate multipartite entanglement. We also introduce the perfect matching diagram (PM diagram), which is a refined directed graph that includes all the essential information on the entanglement generation by an LQN. The PM diagram furnishes rigorous criteria for the entanglement of an LQN and solid guidelines for designing suitable LQNs for the genuine entanglement. Based on the structure of PM diagrams, we compose LQNs for fundamental N-partite genuinely entangled states.
PRÁTICAS DISCURSIVAS DA EDUCAÇÃO ESPECIAL NO BRASIL
Authors: Costa Daniel Marques , Hattge Morgana Domênica
Published: December 2021

O presente artigo tem como objetivo analisar as práticas discursivas e a produção de sentidos acerca da Educação Especial no contexto brasileiro. Para isso, percorreu-se, por meio de um estudo teórico, o movimento histórico e legal da Educação Especial no Brasil desde o período imperial até os dias atuais. A partir desse recuo no tempo, foi possível acompanhar as mudanças e as transformações por que passou essa modalidade de ensino em nosso país e, sobretudo, perceber como os jogos de poder e as relações de dominação estabelecem discursos em determinados momentos históricos de nossa sociedade. Foi possível, ainda, caracterizar esse percurso da Educação Especial no Brasil em três diferentes momentos: o primeiro, em que a Educação Especial é identificada como processos de reclusão, processos esses que têm suas marcas evidenciadas do período imperial até o ano de 1960; o segundo, como processos de integração, com forte expressão durante as décadas de 1960 a 1990; e o terceiro, em que a Educação Especial, a partir da década de 1990, é destacada dentro da ordem discursiva instituída pelo imperativo de Estado, o que a faz assumir, dois importantes papéis na educação das pessoas com necessidades específicas. Um deles é de servir como instrumento para a captura e o controle da conduta desses sujeitos por parte do Estado; e o outro, de atuar como potência, interpondo-se a esse controle e criando, assim, linhas de fuga capazes de valorizar e potencializar a vida dessas pessoas.
EDUCAÇÃO FÍSICA NA EDUCAÇÃO DE JOVENS E ADULTOS: DESAFIANDO OS DOCENTES
Authors: Freitas Adenir Machado de , Neuenfeldt Derli Juliano
Published: December 2021

Na Educação de Jovens e Adultos (EJA), há uma relação entre educação e trabalho. Os discentes são trabalhadores, jovens que buscam sua primeira oportunidade de emprego, aqueles que já frequentaram a escola e buscam regressar pela necessidade de uma melhor escolaridade, uma exigência do mercado de trabalho. Esse contexto desafia os professores de Educação Física escolar em suas práticas pedagógicas. Assim, este estudo teve por objetivo investigar dificuldades e aspectos positivos percebidos por professores de Educação Física da rede pública de ensino de um município do Vale do Taquari/RS, ao ministrarem aulas para alunos da EJA. A pesquisa, que se caracteriza como qualitativa, entrevistou quatro professores de Educação Física. Com relação às dificuldades, uma delas é que os alunos chegam exaustos devido ao trabalho. Outra questão que interfere nas aulas são os problemas sociais dos alunos que afetam a estrutura familiar. Ainda, uma terceira refere-se à diferença de faixa etária. A idade dos alunos varia entre 15 e 62 anos, o que dificulta a proposta das aulas. Quanto aos aspectos positivos, os professores comentam que a Educação Física, ao ensinar sobre as práticas corporais, contribui para conhecerem melhor o próprio corpo. Apesar das dificuldades, os professores contam com total apoio da direção de suas escolas.
Forlagenes priser stiger, budgetterne falder...
Authors: Englev Karin Bettina
Published: December 2021

Den tvungne, årlige to-procents besparelse 2016-2022 betyder, at brugere kommer til at stå uden adgang til litteratur, som er central for deres uddannelse eller forskning.
Editorial: Corporate board structure, strategy and performance in uncertain times
Authors: Osinubi Igbekele Sunday
Published: December 2021

Corporate managers make choices that seek to improve the performance of their organisation. These decisions involve interpreting and framing the environment, developing and implementing programmes and services, and creating processes and structures to monitor and control resources for optimal impact (Brown & Iverson, 2004). Board performs a critical function to monitor environmental trends that might affect organisational performance. The strategy adopted by the corporate board will have a considerable impact on their performance. The literature also suggests that the composition of the board will be contingent upon the characteristics of the firm’s external environment, the demands of its strategy and the salient contextual factors and the past financial performance of the company (Pfeffer & Salancik, 1978). These issues are addressed in the collection of high-quality papers in this issue of Corporate Board: Role, Duties and Composition.
Adding behavior to rationality on M&A deals analysis: Deviations over specialist’s usual praxis and their sources
Authors: López Domínguez Ignacio
Published: December 2021

Value creation may not be enough when considering deals. Avoiding deviations over mergers and acquisitions (M&A) advisor’s standards is a useful behavioral add-on to deals rationality. The investigations on this theme revealed the presence of many different approaches and practices in the decision-making process and managing companies among different countries. This paper is focused on Spain through research built by in-depth interviews and surveys to specialists that shows the main three factors with a capacity to produce deviations and the main deviations created. The factors are the financing needs of the acquirer, the need to do the deal by the seller, and the different nature and role, whether industrial, managerial, or financial of the participants. Deviations found are agreements out of specialists’ usual outputs and affect deal pricing. The presence of these factors should allow capacities of alert, analysis, and bargaining and increase the value of planning, training, and management at deals frames. Rationality based on value creation might be enhanced by the fulfillment of the advisors’ criteria. The main contribution of the paper is that, to avoid deviations, might be considered a behavioral contribution to complement rationality in the complex and uncertain universe of M&A deals.
Learners’ Willingness to Communicate in a Foreign Language: The Role of Informal Digital Learning of English
Authors: Nugroho Arif
Published: December 2021

The trend of online teaching and learning in the age of the COVID-19 pandemic has driven contemporary students to learn English in an informal context outside the classroom. Drawing on this issue, the present study is at the cutting edge of examining the role of Informal Digital Learning of English (IDLE) in affecting students’ willingness to communicate in a foreign language. A total of 156 (male=63; female=93) Indonesian EFL students participated in survey research upon invitation.  The data are obtained by means of an online questionnaire consisting of three parts: (1) willingness to communicate, (2) IDLE, and (3) demographic data. The hierarchical regression analysis results reveal that Frequency of IDLE, Receptive IDLE activity, and Productive IDLE activity are the positive predictors of EFL learners’ willingness to communicate in English as a foreign language. The results indicate that the Indonesian EFL learners are motivated to communicate in English when engaging in a range of IDLE activities. In other words, it is implied that IDLE activities (both productive and receptive) potentially build the communication behavior of Indonesian EFL learners, who learn English as a foreign language and possess a culturally homogeneous society.
Exact mathematical Formula that connect 6 dimensionless physical constants
Authors: Pellis Stergios , Greece Stergios Pellis
Published: December 2021

In this paper are a new formula for the Planck length ℓpℓ and a new
formula for the Avogadro number NA. Also 9 Mathematical formulas that
connect dimensionless physical constants. The 6 dimensionless physical
constants are the Proton to Electron Mass Ratio μ,the Fine-structure
constant α,the ratio Ν1 of electric force to gravitational force between
electron and proton,the Avogadro number NA,the Gravitational coupling
constant αG for the electron and the gravitational coupling constant
αG(p) of proton.
Meir-Keeler condensing operators and applications
Authors: Hadj Amor , Traiki Abdelhak
Published: December 2021

Motivated by the open question posed by H. K. XU in [39] (Question 2:8),
Belhadj, Ben Amar and Boumaiza introduced in [5] the concept of Meir-Keeler
condensing operator for self-mappings in a Banach space via an arbitrary
measure of weak noncompactness. In this paper, we introduce the concept of
Meir- Keeler condensing operator for nonself-mappings in a Banach space via
a measure of weak noncompactness and we establish fixed point results under
the condition of Leray-Schauder type. Some basic hybrid fixed point theorems
involving the sum as well as the product of two operators are also
presented. These results generalize the results on the lines of
Krasnoselskii and Dhage. An application is given to nonlinear hybrid
linearly perturbed integral equations and an example is also presented.
5. Facilitating Behavior Change and Well-being to Improve Health Outcomes:Standards of Medical Care in Diabetes—2022
Authors:   American Diabetes Association Professional Practice Committee
Published: December 2021

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc22-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc22-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
12. Retinopathy, Neuropathy, and Foot Care: Standards of Medical Care in Diabetes—2022
Authors:   American Diabetes Association Professional Practice Committee
Published: December 2021

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc22-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc22-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
17. Diabetes Advocacy: Standards of Medical Care in Diabetes—2022
Authors:   American Diabetes Association Professional Practice Committee
Published: December 2021

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc22-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc22-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
Identity, place and values. On construction and internalization of festival normalities on the examples of music festivals in Poland
Authors: Szymkiewicz Aleksy
Published: December 2021

The aim of this paper is to compare of how two different festivals stimulate specific norms and perceptions, and therefore to present the way in which the visions of the festival cities are reproduced by the festival audience based on the axio-normative orders contained in the missions of the events. Based on the shared symbols and life strategies promoted by festivals, participants (re)build their identity which they manifest in chosen cultural practices. The article attempt to answer the following question: what is shared by festival-goers? Are the main motivations for participating in the vent due to shared musical tastes or also specific values and lifestyles, and consequently a common identity? It has been shown that the values promoted during festivals are declared by their organizers – they are present in the visual identification, seminars, workshops, etc. Festivals create their narratives based on symbols such as logos, attitude smartphones, or festival slogans which contain condensed axio-normative systems that create the boundaries of the community. It influencesthe behavior of festival goers: the city’s vision, ways of spending free time, and their identity. The places where the fieldwork was conducted were: “Henryk Rasiewicz National Festival of Unbreakable and Independent Songs in Kraków”, “Ostróda Reggae Festiva” in Ostróda, and the “Song of Our RootsFestival” in Jarosław.
Tidili Centre – stolica gminy. Embrion struktury miejskiej w środowisku wysokogórskim Maroka
Authors: Vorbrich Ryszard
Published: December 2021

Niniejsze opracowanie przedstawia historię powstania w ukrytej wśród szczytów Atlasu Wysokiego niewielkiej osady zwanej Tidili Centre, stanowiącej dziś rodzaj „embrionu” struktury urbanistycznej. Analiza, odwołująca się do koncepcji procesów długiego trwania, przedstawia kontekst przyrodniczy, historycznyi społeczno-polityczny towarzyszący powstawaniu tego mikromiejskiego środowiska. Osada powstała „na surowym korzeniu” na tradycyjnych ziemiach plemienia Ait Tidili, stając się formalnie stolicą gminy. Pełniąc wiele funkcji gospodarczych, społecznych (administracyjnych) i kulturalnych, omawiana osada tworzy ramy przestrzenne społeczności lokalnej o heterogenicznym charakterze. Jest też wyrazem zmian, jakie zaszły na tym obszarze na przestrzeni czterech dekad, gdzie dotychczas stosunkowo zamknięta i jednorodna lokalna (subregionalna) społeczność włączona została do szerszego systemu wspólnoty narodowej.
SUBJECT AREA “TECHNOLOGY” AND FORMATION OF REGIONAL EDUCATIONAL STRUCTURES
Authors: LISTVIN ALEXANDER A. , GARTH MARINA A.
Published: December 2021

The article considers the role of the subject area “Technology” as the integration basis for the content of general education in the technological training of schoolchildren in the conditions of infrastructure modernization. The authors reveal the relationship between technosphere transformations and secondary vocational education infrastructure, higher education and content tracks in the subject area “Technology”, its role in regional educational systems that ensure the quality of training personnel taking into account the priorities of regional development.
FOREIGN EXPERIENCE IN EXPERT EXAMINING THE QUALITY OF EDUCATIONAL ACTIVITIES AT UNIVERSITIES (BY THE EXAMPLE OF UNIVERSITIES IN AUSTRALIA)
Authors: ROGOZIN ANDREY YU.
Published: December 2021

The article considers foreign experience while analyzing the quality of educational activities at universities. The paper justifies the need to analyze the Australian experience as best and practically unexplored by specialists. The author analyses the Australian system of higher education and the system of examining university activities, comparing the Australian experience with the Russian one, underlying positive and negative features. In the conclusion the author speaks about the necessity of further analyzing Australian steps in the expert examination of university educational activities and the necessity to develop sustained interaction with employers.
ETHNOLINGUISTIC COMMENTARY ON THE DERIVATIONAL-PHRASEOLOGICAL NEST OF A WORD PECH' IN THE NORTHERN RUSSIAN DIALECT DISCOURSE
Authors: DYACHKOVA IRINA N.
Published: December 2021

The article analyzes the cultural and semantic features of the derivational-phraseological nest of the word pech' in the Northern Russian dialects (mainly in the Russian dialects of Karelia and the border regions). Based on the linguistic data, the author reconstructs the idea of pech' in the traditional culture of the Russian North; analyzes the content of the derivational paradigm for the lexeme pech '; determines its secondary meanings associated with the development of space outside the house. The article shows the reflection of pagan ideas and practices in the semantic structure of the word and its derivatives, the interaction between the conceptual fields of “pech’” and “house”, “pech’” and “family”.
Manifestação do Sagrado no conto O defunto (1895) de Eça de Queiroz (1845-1900)
Authors: Rocha Denise
Published: December 2021

Na terceira fase de sua produção literária, José Maria Eça de Queiroz (1845-1900) dedica-se à escrita de obras de conteúdo religioso - hagiografias e manifestações divinas -, entre outras. Baseado em uma narrativa exemplar, citada no Sermão XXV de Maria Rosa Mística, do Padre António Vieira, Eça escreve o conto, O defunto (1895), a respeito do poder da oração do Rosário e da ajuda de Nossa Senhora do Pilar. A temática de louvor à Virgem e a seus milagres tem tradição literária na Península Ibérica, e foi eternizada nas Cantigas de Santa Maria, de Afonso X, o Sábio (1221-1284).
Derechos Humanos en la era digital
Authors: Araújo Luis Felipe De Jesus Barreto , Santos Elenice Rolemberg
Published: December 2021

El estudio se sitúa en el debate sobre la libertad de expresión, su supuesta restricción y su confrontación con otros derechos fundamentales. Además, busca demostrar la importancia de los derechos humanos para que las personas mantengan su derecho a la libertad de expresión. Sin embargo, esta investigación buscó demostrar los impactos de la libertad de expresión en Internet, es decir, analizó los límites del derecho de un individuo a expresarse a costa del derecho del otro en virtud de la imagen, la moral y el tiempo. También, para sustentar los resultados de la investigación, se decidió estudiar las decisiones del tribunal superior brasileño para refutar o confirmar, mientras se estudia, el enfrentamiento de la libertad de expresión en la esfera virtual y otros derechos fundamentales. Se concluye que, ya existe una jurisprudencia de los tribunales superiores brasileños que tienden a garantizar que el individuo que viola los derechos fundamentales de los demás, debe indemnizarlo.
Vacunas para Covid-19: seguridad, elaboración y distribución
Authors: Bonilla Medrano Nathaly , Simancas-Racines Daniel , Montesinos-Guevara Camila
Published: December 2021

Debido a la emergencia sanitaria global causada por la pandemia del COVID-19, tanto la comunidad científica como organizaciones públicas y privadas, juntaron recursos para el desarrollo de vacunas contra la COVID-19. Normalmente, el proceso de creación y aprobación de una vacuna suele tardar varios años, por lo que, organizaciones internacionales como la FDA han otorgado una Autorización por Uso de Emergencia (EUA) para poder agilizar su distribución. El proceso de creación de una vacuna tiene la fase preclínica y las fases clínicas, en las cuales, se analizan su seguridad, eficacia e inmunogenicidad. Sin embargo, no es suficiente la manufactura de la vacuna, sino también garantizar el monitoreo en su seguridad (pos-aprobación) , distribución global y una apropiada divulgación científica a cerca de la misma. Para una apropiada campaña de vacunación , es importante determinar las limitaciones socio-económicas y demográficas de cada país, al igual que los problemas de inequidad en la distribución de vacunas globalmente. Esta revisión, resume la literatura existente acerca de la seguridad de las vacunas que actualmente se suministran en el Ecuador, además, busca informar a los lectores sobre la elaboración de las vacunas y de los retos que enfrenta la inmunización contra el COVID-19
Development of chemical education and science in Lviv Polytechnic school (1877–1918)
Authors:   Lviv Polytechnic National University, Blazhivskyi K. І.
Published: December 2021

On the 150th anniversary occasion of the Department of Chemical Technology at the Lviv Polytechnic National University founding, the activities of chemical departments and faculties at the time of Polytechnic School in 1877–1918 and the conditions of study of students was covered. Creation and transformation of chemical departments and the role of their leaders was considered. Scientific-pedagogical and public activities of famous scientists and teachers such as August Freund, Yulian Medvedskyi, Bronislaw Pawlewski, Roman Zaloziecki, Stefan Niementowski, Ignacy Moscicki, their contribution to development of Lviv Polytechnic and Galicia was characterized.
Study of the composition of drugs for the treatment of diseases of the nose cavity
Authors:   Lviv Polytechnic National University, Parashchyn Zh.P. , Lobur I. P. ,   Lviv Polytechnic National University, Kyrychuk A.O. ,   Lviv Polytechnic National University, Bryda O. R. ,   Lviv Polytechnic National University, Stadnytska N. E. ,   Lviv Polytechnic National University
Published: December 2021

Drugs of group R01, according to the АTC- classification used in the treatment of diseases of the nasal cavity by composition and dosage form, were studied. The dependence of the therapeutic effect of drugs on the chemical structure of the active substance, possible combinations of active substances belonging to different pharmacological groups (sympathomimetics, corticosteroids, and antihistamines), which determine their specific effect on the human body, are analyzed. These active substances are found in both mono- and multi-component drugs. In combination drugs, other compounds of natural and synthetic origin are also used to enhance the therapeutic effect.