bluuebunny/crossref_metadata_2025 huggingface dataset:
Pattern and trend of cancer in Saurashtra region in Gujarat state of India, a hospital-based study
Authors: Saini Surendra K. , Srivastava Shelly , Patel Pritesh , Sarvaiya Jitesh
Published: January 2024

Background:

Cancer is growing concern for every country. Reliable data is a source to define the magnitude of the problem, which then helps to plan for necessary action. This epidemiological study involves the collection and analysis of hospital registry data to assess the quantum of the problem of cancer over a five-year period from 2012–16 and to plan priority action.

Materials and Methods:

Hospital-based data for five years from 2012–2016 was retrieved from the department of radiotherapy at M. P. Shah Government Medical College, Jamnagar, Gujarat, India, and analysed to define the magnitude of the problem. All data was studied using Microsoft Excel 2016.

Results:

A total of 7355 patients were registered between 2012 and 2016, out of which 62 percent were male. Cancers of the cervix and uterus were discernibly less common in the Saurashtra region and accounted for only 12.37% of all cancers in females. Lung cancer was the leading cancer as a single site in males (24.13% of all cancers in males) and breast cancer in females (37.36% of all cancers in females). Head and neck cancer, all sites clubbed, was most common in males (42%). Jamnagar taluka represented around 50% of all cases at the study center.

Conclusion:

Tobacco-related cancers were most common in the male population, and stringent implementation of a national tobacco control program is the most appropriate measure to curtail incidences and hence mortality in this male population. Non-modifiable risk factors like gender-related cancer were more common in the female population, and resource-appropriate screening is a suitable option for these diseases. A population-based cancer registry is required to further define the pattern pertinently, or an epidemiological study is required to find causes of the noticeably lower incidence of cancer of the cervix,.
Epithelial myoepithelial carcinoma: A case report
Authors: Kaur Ravinder , Melgandi Wineeta , Rathi Arun Kumar , Singh Kishore , Rahman Fazlu , Mandal Shramana
Published: January 2024

Epithelial myoepithelial carcinoma is a rare tumor with the parotid gland being the most common primary site of origin. The tumor may also very rarely originate in minor salivary glands of the soft palate. Due to the rarity of its occurrence and histogenesis, clear-cut therapeutic guidelines are not defined. The present report describes the case of a 56-year-old female patient who was diagnosed to have epithelial myoepithelial carcinoma (EMC) of the minor salivary gland of the soft palate, Stage T2 N0 M0 (Stage group II). The patient was treated with radical radiotherapy followed by adjuvant chemotherapy and is alive with no evidence of disease after 12 months following the end of treatment.
Evaluation of the efficacy of adjuvant radiotherapy versus chemoradiotherapy in patients with salivary gland tumors
Authors: Aral İpek P. , İnan Gonca A. , Gökçe Ezgi , Gani Zerrin , Ergün Dilem , Arslan Nalan , Akinci Muhammet B. , Tezcan Yılmaz
Published: January 2024

Aims:

The aim of this study was to compare the efficacy of adjuvant radiotherapy (RT) versus adjuvant chemoradiotherapy (CRT) in patients with salivary gland tumors (SGTs).

Materials and Methods:

Data from patients who underwent adjuvant RT for a diagnosis of SG cancer at Ankara Atatürk Education and Research Hospital, Ankara Numune Education and Research Hospital and Ankara Bilkent City Hospital between September 01, 2009 and September 01, 2022 were analysed retrospectively. We evaluated the efficacy of RT alone versus CRT in these patients in terms of acute response, treatment tolerance, overall survival (OS), and disease-free survival (DFS).

Results:

Fifty-five patients who underwent RT between September 14, 2009 and August 04, 2022 at Ankara Atatürk Education and Research Hospital, Ankara Numune Education and Research Hospital and Ankara Bilkent City Hospital were included in this study. Eight patients who did not meet the study criteria were excluded; thus, the analysis was performed for 47 patients. The median follow-up period was 60 months (range: 6-160 months). The median patient age was 53 years (range: 18-86 years). Thirty-nine patients (83%) had parotid tumors and eight patients (17%) had submandibular cancer. The time from surgery to RT was 48 days (range: 20-126 days). Intensity-modulated radiotherapy was administered to all patients and the median RT dose was 66 Gy (range: 52-70 Gy). Concomitant chemotherapy (CCT) (40 mg/m2 of cisplatin weekly) was administered to 13 patients (27.7%). Acute adverse events were observed in 17 patients (36.2%). Interruption of RT was noted for only six patients (12.8%), and this proportion did not differ significantly between the CRT and RT-only arms (P = 0.538). Acute side effects were observed in 17 patients (36.2%), and there were no significant relationships between acute side effects and the administration of CCT (P = 0.112). Recurrence was observed in 10 patients (21.3%). All recurrences were locoregional and no distant metastases were observed during the follow-up period. The median DFS of the patients was 48 months (range: 4-160 months), 1-year DFS was 86%, 2-year DFS was 83.5%, and 5-year DFS was 77.9%. There was no statistically significant difference in DFS between the adjuvant CRT and RT-alone arms (P = 0.114). At the date of last follow-up, 14 patients (29.8%) had died. The median OS of the patients was 58.5 months (range: 6-160 months), 1-year OS was 91.4%, 2-year OS was 86.8%, and 5-year OS was 78%. There was no statistically significant difference in OS between the adjuvant CRT and RT-only arms (P = 0.453).

Conclusion:

Stage was identified as the most important prognostic factor for DFS and OS. No significant differences in OS, DFS, or acute side effects were observed between the CRT and RT-only arms. Additional studies are needed to identify the subgroup of SGT patients for which CRT is most warranted.
Three-way Philadelphia Translocation [t(46, XX, t(9;22;16) (q34;q11.2;q24)] in Chronic Myeloid Leukemia: A Report of Two Cases with Review of the Literature
Authors: Bhardwaj Mohit , Mishra Sourav K. , Gupta Aastha , Mehta Prashant , Sharma Shivani , Mohanty Sambit K.
Published: January 2024

Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm that is genetically characterized by the presence of the Philadelphia (Ph) chromosome. Variant Ph translocation has been observed in 5% to 10% of the CML cases. In the previous studies, many different types of variant Ph translocations have been observed involving chromosomes 1p36, 3p21, 5q13, 6p21, 9q22, 11q13, 12p13, 17p13, and 10p15. According to the published literature, only two cases with the complex translocations involving long arm of chromosome 16 at band q24 have been reported. We report two female patients with complex translocation (three-way) involving chromosomes 9, 22, and 16 at breakpoint q24 and both patients responded well to Imatinib. The present study included 469 patients of clinically diagnosed CML patients who were referred for cytogenetic analysis to our laboratory. Cytogenetic analysis was performed by GTG banding, and the karyotype was designated according to the International System for Human Cytogenetic Nomenclature. Fluorescence in situ hybridization (FISH) analysis was performed for complex and variant BCR-ABL cases. Of total 469 cases, 248 patients showed classical Ph chromosome [t(9;22)(q34;q11.2)], 198 cases were normal, and 23 patients had variant and complex Ph chromosome translocation. Two patients showed three-way translocation involving long arm of chromosomes 9, 22, and 16 at band 9q34, 22q11.2, and 16q24. In this report, patients with variant Ph translocation did not have a significantly different outcome as compared to the classical translocation. Both cases responded well to Imatinib.
Asymptotics of multivariate sequences in the presence of a lacuna
Authors: Baryshnikov Yuliy , Melczer Stephen , Pemantle Robin
Published: January 2024

We explain a discontinuous drop in the exponential growth rate for certain multivariate generating functions at a critical parameter value in even dimensions

d \geq 4

. This result depends on computations in the homology of the algebraic variety where the generating function has a pole. These computations are similar to, and inspired by, a thread of research in applications of complex algebraic geometry to hyperbolic PDEs, going back to Leray, Petrowski, Atiyah, Bott and Gårding. As a consequence, we give a topological explanation for certain asymptotic phenomena appearing in the combinatorics and number theory literature. Furthermore, we show how to combine topological methods with symbolic algebraic computation to determine explicitly the dominant asymptotics for such multivariate generating functions, giving a significant new tool to attack the so-called connection problem for asymptotics of P-recursive sequences. This in turn enables the rigorous determination of integer coefficients in the Morse–Smale complex, which are difficult to determine using direct geometric methods.
Combate penal às fake news? Sobre a relação da teoria da criminalização com a verdade
Authors: Soares Hugo
Published: January 2024

Given the unsatisfactory state of the debate on the relationship between criminalization theory and truth, this paper aims to discuss the limits of its criminal protection. To this end, the two different forms of protection, direct and indirect, are analyzed, and their problems, limits, and specificities are considered and discussed. In this context, a brief exploration of the current state of Criminalization Theory is also promoted, debating the insufficiency of considerations exclusively guided by the theory of legal good and the insertion of so-called deontological barriers in this theoretical framework. Ultimately, it is concluded that the direct criminal protection of truth will always be illegitimate because it violates what has been called the deontological truth barrier, while its indirect criminal protection will only be legitimate in cases where an untruth poses at least a concrete danger to other protected legal good.
A Study on the Challenges and Legal Issues arising from Chinese investment in Bangladesh Natural Resources and Infrastructure
Authors: Rashid Al-Mamnur
Published: January 2024

This study focuses on the challenges and legal issues surrounding Chinese investment in Bangladesh's natural resources and infrastructure. It looks at the impact of Chinese investment on the country's resources and infrastructure, including any legal and regulatory issues that may arise. The study may examine how Bangladesh's laws and regulations protect the country's natural resources and infrastructure from foreign investment, and whether these laws are adequate to ensure that the country's resources are being used sustainable and in a manner that benefits the local communities. Additionally, the study may look at the role of international law and international organizations in mediating disputes between Bangladesh and Chinese investors. I have mentioned foreign investments in natural resources of Bangladesh e.g. natural gas, petroleum oil, coal and water resources. Until now, China only invests in a couple of sectors relating to natural resources. These investments are infrastructure projects e.g. power generation, construction, port establishment, agro-processed product, electrical and electronics, light engineering, roads, railways, power plants, and water treatment facilities, etc.
This is a second generation Chinese BIT that incorporated general Characteristics of BITs of that era. Under this BIT, Regarding the dispute of expropriation, an ad hoc arbitral tribunal can be formed which would determine its own procedure, but the first negotiation shall take place between the parties to solve the dispute. Under these agreements, the disputes shall be settled by applying generally recognized principles of international law accepted by the parties.
The Calcutta Marwaris and the Swadeshi Movement: In the Context of Boycott and Swadeshi Politics (1905-1907)
Authors: Shaikh Imran
Published: January 2024

At the dawn of the 20th century, an organized struggle against the partition of Bengal significantly influenced the trajectory of Indian politics. The Swadeshi movement engendered political extremism within the realm of Indian nationalism, leading a contingent of educated Bengalis to take up arms against British rule. In these circumstances, Bengali leaders adopted the policies of 'Boycott' and 'Swadeshi' to undermine British economic interests in Bengal. This paper seeks to explore the role played by the Marwari community of Calcutta in the anti-partition movement of 1905. During that era, the Marwaris were integral to the European trading system. They procured raw materials from various parts of the country for export and served as distributors of foreign products in the local market. Marwari traders were aligned with the British in the realm of commerce. Given this context, it is natural to question how the Marwari traders of Calcutta reacted to the boycott of foreign goods. What if we were to uncover, albeit sparingly, instances of Marwaris supporting the anti-partition boycott movement in history? This paper aims to address the following questions to comprehend the involvement of Calcutta's Marwaris in the 1905 Swadeshi Movement. Firstly, to what extent did the policy of boycotting foreign goods succeed within the Swadeshi movement? Secondly, what was the impact of the 'Boycott' and 'Swadeshi' policies on the Calcutta Marwaris? And thirdly, did the Calcutta Marwaris indeed participate in the Swadeshi Movement, and if so, what motivated their involvement? Most prevailing studies have dismissed the participation of the Marwari Community of Calcutta in the Swadeshi movement. This paper aims to uncover the answers to these questions and shed light on the extent of the Marwari community of Calcutta's involvement in the Swadeshi movement.
Node Replication: Theory And Practice
Authors: Kesner Delia , Peyrot Loïc , Ventura Daniel
Published: January 2024

We define and study a term calculus implementing higher-order node
replication. It is used to specify two different (weak) evaluation strategies:
call-by-name and fully lazy call-by-need, that are shown to be observationally
equivalent by using type theoretical technical tools.
Sexual Behaviour in Autistic Children: An Applied Behaviour Analysis Approach
Authors: Grigorescu Carmen Gabriela
Published: January 2024

This study focuses on the sexual behavior of children with autism, providing a detailed account of behavioral aspects in this specific developmental domain. Using Applied Behavior Analysis (ABA) methods, the research aims to investigate and understand how children with autism exhibit sexual behaviors within the unique context of their disorder. The diversity of sexual behaviors in this group of children is explored by thorough observation and assessment, while identifying potential influences of individual and environmental factors. Applied Behavioural Therapy (ABA) is an evidence-based, effective and scientifically founded intervention for autistic children. ABA is focussed on understanding and changing unwanted, problem behaviors by using behavioral principles. The therapy is tailored to the individual needs of the child, aiming to develop social, communication, and academic skills.
PENGARUH DIGITAL MARKETING DAN CITRA MEREK TERHADAP VOLUME PENJUALAN PRODUK KOPI KEDERA PADA PT. MULKI ABADI MANAGEMENT DI MEDAN
Authors: Rabudin Rabudin , Zahri Cut , Zikri T.M
Published: January 2024

Tujuan dari penelitian untuk mengetahui pengaruh digital marketing dan citra merek terhadap volume penjualan pada PT. Mulki Abadi Management di Medan. Jenis data yang digunakan dalam penelitian ini adalah data kuantitatif yang menggunakan survey dan kuisioner atau angket kapada konsumen Kopi Kedera pada PT.Mulki Abadi Management di Medan. Hasil penelitian menunjukkan bahwa: Hasil tes uji t statistik digital marketing sebesar 2,917 lebih besar t tabel yaitu 1,668 dengan nilai signifikansi 0,005 < 0,05 hal ini menunjukan variabel digital maketing berpengaruh signifikan terhadap variabel volume penjualan. Hasil tes uji t statistik citra merek sebesar 4,546 lebih besar t tabel yaitu 1,668 dengan nilai signifikansi 0,000 < 0,05 hal ini menunjukan variabel citra merek berpengaruh signifikan terhadap variabel volume penjualan. Hasil uji F dapat disimpulkan bahwa digital marketing dan citra merek secara bersama-sama berpengaruh signifikan terhadap volume penjualan yang dibuktikan dengan hasil uji F-hitung > F-tabel sebesar 51,114 > 3,138 dan nilai signifikansi (0,000 < 0,05). Jadi, dapat disimpulkan bahwa secara simultan variabel digital marketing dan citra merek berpengaruh terhadap volume penjualan pada PT. Mulki Abadi Management di Medan.
PENGARUH HARGA TIKET DAN CITRA PERUSAHAAN TERHADAP KEPUTUSAN PEMBELIAN PADA PT. ANGKASA TOUR & TRAVEL MEDAN
Authors: Gauri Beby Sofia , Amri M , Alfirah Alfirah
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pengaruh harga tiket dan sitra perusahaan terhadap keputusan pembelian pada PT. Angkasa Tour & Travel Medan.PT. Angkasa Tour & Travel adalah salah satu agen travel yang melayani paket wisata ke luar negeri, urus paspor, visa dan kitas. Populasi merupakan sumber data dalam penelitian tertentu yang memiliki jumlah banyak dan luas. Populasi dalam penelitian ini adalah konsumen yang pernah melakukan keputusan pembelian tiket di PT. Angkasa Tour & Travel Medan sebanyak 255 konsumen., jumlah sampel yang digunakan setelah dibulatkan yaitu sebanyak 72 konsumen. Teknik analisa yang dipergunakan untuk menjawab hipotesis dengan analisis regresi linier.Hasil pengaruh Harga Tiket terhadap Keputusan Pembelian diperolehsignifikansi 0,004 (t < 0,05) sehingga Harga Tiket secara parsial berpengaruh signifikan terhadap Keputusan Pembelian.Hasil pengaruh Citra Perusahaan terhadap Keputusan Pembelian diperoleh nilai signifikansi 0,082 (p > 0,05) sehingga Citra Perusahaan secara parsial tidak berpengaruh signifikan terhadap Keputusan PembelianJika dilihat dari nilai signifikan uji F hitung adalah 0,004 yaitu < 0,05 yang berarti hal ini menunjukan bahwa variabel Harga Tiket dan Citra Perusahaan secara simultan berpengaruh signifikan terhadap Keputusan Pembelian.
PENGARUH KUALITAS PELAYANAN DAN PENERAPAN SISTEM E-BILLING TERHADAP KEPUASAN WAJIB PAJAK DI KANTOR PELAYANAN PAJAK PRATAMA MEDAN BARAT
Authors: Tanjung Desi , Rangkuti Sahnan , Al Firah Al Firah
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pengaruh kualitas pelayanan dan penerapan sistem e-billing terhadap kepuasan wajib pajak di Kantor Pelayanan Pajak Pratama Medan Barat. Sampel penelitian ini berjumlah 100 responden dari total populasi sebanyak 239.151 wajib pajak dan menggunakan metode kuantitatif. Pengumpulan data melalui kuesioner dan analisis data dilakukan dengan menggunakan uji regresi berganda. Hasil penelitian menunjukkan bahwa variable kualitas pelayanan secara parsial berpengaruh positif dan significant erhadap kepuasan wajib pajak denganthitung> ttabel sebesar 4,561>1,661 berarti Ho ditolak dan Ha diterima. Variabel penerapan sistem e-billing secara parsial berpengaruh positif dan signifikan terhadap terhadap kepuasan wajib pajak denganthitung> ttabel sebesar 2,637 >1,661 berarti Ho ditolak dan Ha diterima. Sedangkan secara simultan diperoleh adanya pengaruh yang positif dan signifikan antara kualitas pelayanan dan penerapan sistem e-billing terhadap kepuasan wajib pajak dengan nilai Fhitung>Ftabelsebesar 24,383>3,090 berarti Ho ditolak dan Ha diterima. Berdasarkan hasil koefisien determinasi yang diperoleh sebesar 0,335 maka 33,5% variasi variabel kepuasan wajib pajak ditentukan oleh kedua variabel independen yaitu kualitas pelayanan dan penerapan sistem e-billing, sisanya dipengaruhi oleh variabel lain.
ANALISIS PERANAN MANAJEMEN PRODUKSI DALAM MEMINIMALISIR PRODUK GAGAL PADA PT. SUMATERA HAKARINDO DI MEDAN
Authors: Aurel Nurul , Nasution Umar Hamdan , Al Firah Al Firah
Published: January 2024

Penelitian ini bertujuan untuk mengetahui dan menganalisa bagaimana peran, kendala dan solusi manajemen produksi dalam meminimalisir produk gagal terhadap PT.Sumatera Hakarindo Medan.Identifikasi masalah dalam penelitian ini meliputi terjadinya kesalahan dalam mengontrol mesin, Bahan yang tidak sesuai seperti bahan rusak atau koyak yang terjadi pengerjaan ulang dalam produksi, dan produksi yang belum optimal sehingga dalam percetakan tidak sesuai dengan standar yang telah ditetapkan.Metode penelitian yang digunakan adalah kuanlitatif. Jenis data yang digunakan adalah dataprimer dan sekunder. Teknik pengumpulan data mencakup pengumpulan data, reduksi data, observasi dan wawancara untuk menganalisa laporan, penyajian data, penarikan kesimpulan data PT. Sumatera Hakarindo Medan. Hasil penelitian menunjukkan bahwa kesalahan proses produksi tidak hanya dari sisi operator, namun karena quality control yang tidak teliti dalam melakukan pengecekan bahan. Seperti bahan koyak,bahan rusak, pewarnaan tidak merata dan tidak sesuai ukuran (standarisasi).Setiap adaproduk gagal pasti ada solusi untuk perbaikan karena jika terus terjadik esalahan dan pengerjaan ulang akan mengeluarkan biaya dan terhambatnya prosesproduksi lanjutan. PT. Sumatera Hakarindo Medan meminimalisirkan produk gagal saat proses produksi agar konsumen lebih percaya dan meningkatkan jumlah pemesanan produknya
Cover Desember 2023
Authors: Desember 2023 Cover
Published: January 2024

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Investigating Pre-Columbian Gold and Copper in Costa Rica – Ores, Mines and Artefact Production
Authors: Gassmann Guntram , Klein Sabine , Schäfer Andreas , Welk Elias , Wester Katrin
Published: January 2024

The wealth of pre-Columbian gold, copper and guanín (an alloy consisting mainly of gold and copper; also tumbaga) artwork of Costa  Rica suggests that exploitation of its abundant ore deposits goes back way before the Spanish conquest. The name of Costa Rica itself in fact alludes to the large numbers of golden metal objects worn by the indigenous peoples upon arrival of the conquistadors. Up to now, however, very little is known about pre-Columbian mining in the country or the raw material provenance of these artefacts.In a transdisciplinary project, we aim to reconstruct the metallurgical process chain by combining (mining) archaeological research with geochemical analysis of local ores and metal artefacts using a combination of different techniques. We identified four major gold and  copper districts with different mineralisation types, which are the focus of our fieldwork-based research. They are surveyed for  potential signs of pre-Columbian metal production and sampled for ores and their processing remains. On the other side of the process chain, we focus on the metal artefacts in museum collections. They are systematically registered in a database, which serves as a basis to identify correlations with the geochemical signatures of the artefacts, and to retrace potential links to possible areas of origin or different workshops. Once the necessary basic data have been collected, we will focus on economic and socio-cultural aspects of  metal production and circulation. The results from Costa Rica will be put into perspective of New World early metallurgy and can provide a starting point for future research between Mesoamerica and the Isthmo-Colombian region.
Does Every Picture Really Tell a Story?
Authors: Baetens Jan
Published: January 2024

The present article deals with the forgotten genre of the film photonovel and the magazines that published this kind of movie adaptations in the decade between 1955 and 1965. It studies the various models that were copied or appropriated by this genre that was most popular in Italy and France. The main focus lies on the manner in which the layout principles of these magazines manipu-lated the narrative and sequential principles of the movies they adapted. How did they succeed in offering new forms of visual montage that enabled them to combine storytelling on the one hand and portrait photography on the other? Finally, the paper discusses the differences between the better-known movie story magazines which fictionalized the movies while illustrating them with set pictures, and the film photonovel, in which word and image combinations were directly inspired by the photonovel magazines.
Die Wohnzeitschrift als Wäʼende-Moderatorin
Authors: Wagner Alexander
Published: January 2024

This paper deals with the ›Wende‹ volume (1990) of NEUES WOHNEN, a GDR home design magazine, having previously operated as kultur im heim for many years. The aim is to show how during the ›Wende‹—the period following the Peaceful Revolution of 1989—the sphere of East German housing, rarely focused on by media at that time, was negotiated in a printed periodical during the process of the GDR-dissolving German reunification. Doing so, the journal’s gaze is a specifically ›East German‹ one, confronted with new epistemic ingredients and actors when opening GDR-specific ways of negotiation. With special attention to the print order and semantics circulating between the issues, individual magazine sections are selected to demonstrate two aspects: how the magazine faces problems of providing home design models in which Eastern German identities can be lived out as Federal German ones; and how, through these very efforts, the restitution of the value ›bourgeois‹ (›bürgerlich‹) becomes important for the journal’s self-understanding after the ›Wende‹.
AGNI AND IT’S ROLE IN THE HEALTH AND DISEASE
Authors: M S Keertan , Shete Hemlata
Published: January 2024

Agni is the factor governing the process of digestion &transformation. Agni is responsible for the digestion, absorption, and assimilation of ingested food. Some scholars opined that the functional form of agni exists as pitta,
i.e., agni resides in the body as pitta. The varieties of agni have been enumerated in the Ayurvedic texts according
to the functions and site of action; Agni has been divided into 13 types, i.e., one Jataragni, five Bhutagni, and
seven Dhatvagni. Jatharagni is the most important, digesting four kinds of food and transforming them into Rasa
and Mala. The five Bhutagnis act on the respective Bhutika portion of the food, nourishing the Bhutas in the
body. The seven Dhatvagni act on the respective dhatus; each Dhatu is broken into three parts. In this way, the
entire transformation process consists of two types of products – Prasad (essence) and Kitta (excrete). The former
is taken for nourishment while the latter is thrown out, which otherwise defiles the body if it stays longer. The
disease origin and pathogenesis involve the disturbance and vitiation of agni. So, the effective way to tackle this is
to protect and maintain the agni. The ultimate essence of treatment lies in the correction of Agni, as it is the primary driving force in initiating the disease process.
A CLINICAL STUDY TO EVALUATE THE EFFICACY OF MANJISHTADYA TAILA
AND Its MODIFIED FORM OF CREAM IN TWAK VAIVARNYA
Authors: Z Sha Summaiyah , B Sathyanarayana , Nayak Vatsala
Published: January 2024

External beauty has gained a lot of attention & demand in ancient times as well as in today’s era. Twak Vaivarnya
refers to the abnormal pigmentation of the skin, often resulting in uneven patches or dark spots. It is a common
disorder affecting any age group. It affects the sex invariably. It is not limited to any particular class of society.
Vyanga (dark spots on face) is a condition of localized hyper melanosis which affects only the skin of the face.
Topical applications mentioned in modern cosmetics containing synthetic or chemical substances are known to
have several adverse effects including local hypersensitivity reactions. Hence, there is always a demand for safe
and effective topical applications to manage hyperpigmented skin diseases. A total of 30 candidates were selected
for the present study. In Control Group 15 candidates were given classically prepared Manjishtadya taila and in
Study Group 15 candidates were given with Manjishtadya taila cream in Randomized open label parallel group
exploratory study. A comparative clinical study was planned into Twak vaivarnya to elicit whether the modified
tropical dosage form is showing equal or comparable clinical efficacy in clinical scenario. The MASI score was
considered to assess the effect of treatment. Score was compared before and after treatment both in Group A and
Group B, highly significant result was observed with P-0.000.
In the present study, Manjishtadya taila and Manjishtadya taila cream both showed equal effectiveness, but statistically Manjishtadya taila had better results.
CLINICAL EFFICACY OF ERAND SNEHA IN MANAGEMENT OF ACUTE NE-CROTISING PANCREATITIS: A CASE REPORT
Authors: H. Solanki Nirali , A. Patel Naiya , Jaybhaye Sulakshana R. , Kendre Manchak
Published: January 2024

Acute pancreatitis with local and systemic complications should be managed through a multi- disciplinary approach. Delays in assessment or mismanagement may lead to serious consequences. The existing treatment of this disease is mollifying and expensive. Cost-effective management of acute necrotizing pancreatitis
with Ayurveda medicines within time constraintsand without any complications is encouraging. CASE PRESENTATION: In this case study, a 45-year-old male patient’s diagnosis of pancreatitis was established on the basis of
the revised Atlanta classification. As per morphological classification, the patient was of necrotizingpancreatitis and
severity grade was moderate as there were local complications. MANAGEMENT AND OUTCOME: The patient
was hospitalized and prescribed Murchit Erand Sneha 100ml at 10 pm daily. The result was assessed by applying
a numerical pain assessment scale to subjective and objective findings. On the 25th day patient was found free
from signs and symptoms. DISCUSSION: In pancreatitis, Srotorodha is an important phenomenon, and Erand
Sneha causes Sampraptivighatana by its Srotoshodhana effect. CONCLUSION: Management of acute necrotizing pancreatitis by using Erand Sneha within time constraints and without any complications is encouraging that
needs to be further evaluated on a large number of subjects to bring some concrete conclusions and better treatment modality.
A ROLE OF AYURVEDA IN THE MANAGEMENT OF KARNABADHIRYA (SEN-SORINEURAL DEAFNESS) - A CASE STUDY.
Authors: Dhayagude Latabai , Magar Sunita
Published: January 2024

Acharya Sushruta described Badhirya in 28 Karnagata rogas in Shushrut Samhita. [1].Karna Badhirya is a medical problem that is considered a disability in all age groups of people. Hearing impairment among elderly people
is a significant issue, and a person with hearing loss may be unable to hear. There is a rise in cases of hearing loss
reported post-pandemic among the younger generation, too. Lack of communication makes the person frustrated,
lonely, and depressed [2. In the present study, pre-and post-treatment hearing loss was assessed on an audiometry
scale. A 45-year-old male came to OPD complaining of decreased hearing capacity and tiredness at the end of the
day. Audiometry report showed moderate sensorineural hearing loss in the bilateral ear and treated with Nasya
with Madhukadi tail(4) 3 cycles, three cycles of Madhukadi tail Karnapoorana(5)
, Sarivadi vati6) 250mg thrice a
day with lukewarm water or milk for one month. Pre- and post-audiometry revealed that his hearing capacity improved from moderate to mild in both ears. Sensory neural hearing loss occurs when there is a problem in the sensory apparatus cochlea or the pathway of conduction of nerve impulses to the brain(3). SNHL can be peripheral or
central. It can be congenital or acquired. Decreased hearing capacity results from damage to hair cells, which can
be managed by Ayurveda treatment nasya, Karnapoorana with Vatashaman chikitsa. With this study, we can treat
this type of hearing loss without any surgical intervention and help them live their life better.
AYURVEDIC OF CEREBRAL PALSY: A CASE REPORT
Authors: Langote Vrushali P. , Bholane Rajesh , Ghadage Indrajeet , Hase Pramod
Published: January 2024

Cerebral palsy is a common chronic motor disability among developmental disorders. Cerebral palsy is the leading cause of childhood disability affecting cognitive function and development. The worldwide incidence is 1.5 to
3 per 1000 live births. Cerebral palsy is known as a non-progressive neuromotor disorder of cerebral origin. Motor disorders of cerebral palsy are accompanied by disturbances of sensation, perception, cognition, communication, and behavior. In Ayurveda, there is no single condition that exactly shows similarity with cerebral palsy.
Various panchakarma procedures like Sarvang Snehan, Shalishatik Pind Sweda, and Matra Basti are found to be
beneficial in the management of cerebral palsy in children. The present study reported a case of cerebral palsy
diagnosed and observed marked improvement.
smart working y su futuro normativo en España: propuestas a partir de la experiencia italiana
Authors: Ruiz Saura José Enrique
Published: January 2024

Recientemente y, sobre todo, a partir de la llegada de la pandemia, ha aumentado el interés por implantar alternativas que permitan llevar a cabo el trabajo a distancia. En este sentido, el smart working supone una clara ruptura con las rigideces clásicas en torno a un horario y lugar de trabajo definido. No obstante, al igual que ocurrió en su momento con el teletrabajo, la regulación de esta realidad no sigue un desarrollo homogéneo en los países de nuestro entorno. Muestra de ello es que Italia, a diferencia de lo que ocurre en España, sí está generando en los últimos años contenido normativo para regular el smart working, tanto de forma heterónoma como autónoma. El presente trabajo pretende abordar esta situación y aspira a hacer aportaciones que puedan ser útiles de cara a un futuro debate regulatorio sobre el smart working en nuestro país.
Determinants of company bankruptcy before and during the Covid 19 Pandemic
Authors: Haris  , Sandra Amelia
Published: January 2024

Financial distress or financial difficulty is a condition where the company cannot fulfill its long-term and short-term obligations. If this condition is allowed to drag on, the company will either go bankrupt or be liquidated. Financial distress is measured using the Springate. The initial sample was 25 companies listed on the Indonesia Stock Exchange before 2018, of which only 22 companies were found eligible. Among them, nine companies are considered outliers. Therefore, only 13 firms were considered the effective sample. Since the study context is three years, we arrive at 39 data units finally used as the sample. The data source was obtained from the official website of the Indonesia Stock Exchange. Multiple linear regression shows that liquidity positively influences the Springate value, indicating decreased financial distress. Business diversification and leverage have no significant effect on financial distress. The conclusions may be different if different methods are used. Further research is suggested for the Zmijewski or Grover model for more convincing results. Further research can use the Zmijewski or Grover models.
Plagiarism Check
Why is the smartphone market in Indonesia declining?
Authors: Siagian Dergibson , Dema Yosef
Published: January 2024

Technology, particularly communication and information technology, is essential for everyone. As this technology advances, competition among cell phone manufacturers becomes more intense. This is the primary reason that mobile manufacturing companies compete to innovate in order to create mobile products that will catch the attention of market consumers. Cell phones appear to be a basic human requirement. But there is a new irony for Indonesia. Despite a 1.05% increase in population, the smartphone market in Indonesia fell by 11.9% in the first quarter of 2023 compared to the same quarter in 2022. The goal of this study is to determine which factors influence purchase intentions and which factors are the most likely cause of a decrease in purchasing intentions. The study's findings show that the four independent variables, product quality, brand image, brand prestige, and brand trust, all have a positive and significant effect on purchase intention. If there is a decrease in purchase intention, it is reasonable to suspect that the cause is the smallest value, which is far below the other three independent variables.
Plagiarism Check
Implementación del modelo tríada de riesgos, para determinar la probabilidad de falla en ductos: caso corrosión externa
Authors: Betancur-Ríos Juan David , Rojas-Cataño Nora Yamile
Published: January 2024

En este documento se describe y se trata un caso de aplicación en la industria de transporte de hidrocarburos por ductos del denominado algoritmo probabilístico de la tríada de riesgos discutido por Kent Muhlbauer (o algoritmo del Modelo de Referencia de Riesgo Cuantitativo), para establecer la probabilidad de falla (PoF) de un evento, en particular de la amenaza corrosión externa. El modelo utiliza matemática probabilística para combinar las variables y capturar tanto los impactos individuales como la acumulación de efectos menores, a través de las compuertas lógicas OR y AND. El uso de estas compuertas lógicas en modelos de riesgos representa una mejora evidente sobre la mayoría de los métodos más antiguos, ya que permite obtener una mejor representación de la forma en que se comportan los parámetros que materializan una amenaza. En este modelo, las variables que afectan la PoF se agrupan en tres categorías o elementos: exposición, mitigación y resistencia, que se representan en función de la amenaza o mecanismo de daño potencial al cual está sujeto el activo en estudio. Luego de obtener el valor de PoF, este se contrasta con los valores numéricos asociados con la probabilidad de falla en la Tabla 4.2 de API RP 581, se cruza con los resultados de CoF y de este modo se obtiene un ranking de riesgo que permite optimizar los recursos al aplicarlos a los activos de mayor riesgo. Se presentan los resultados luego de aplicarlos a la amenaza corrosión externa.
Aplicación web para práctica con vectores y soporte educativo bajo el modelo de Educación Basada en Web
Authors: Peredo-Valderrama Rubén , Peredo-Valderrama Iván
Published: January 2024

La propuesta presenta una aplicación web para práctica con vectores en el plano cartesiano xy, siendo una herramienta de apoyo en materias como: mecánica, cálculo vectorial, álgebra lineal, electromagnetismo, etc., constituyendo una herramienta avanzada donde los estudiantes practiquen sus saberes de una manera práctica, en conformidad con el modelo de Educación Basada en Web (Web Based Education, WBE por sus siglas en inglés). Los vectores son un concepto extensamente empleado en diferentes materias, pero este concepto es complejo, complicado de comprender, y ante la crisis sanitaria por COVID-19 que seguimos viviendo hasta el momento, ha expuesto la necesidad de herramientas de apoyo para educandos y educadores, con el objetivo de complementar sus clases diarias, con actividades prácticas para crear experiencias más enriquecedoras en las aulas. La propuesta presentada busca producir actividades prácticas multimedia con vectores, para ecuaciones, suma y resta de vectores; a través de la personalización de los vectores para multiplicación escalar configurando los coeficientes de la ecuación del vector, renderizando las características de los vectores como: ángulo, componentes del vector y magnitud. La propuesta presentada se ajusta con la designada Educación 4.0, apoyando proyectos y competencias con vectores, proveyendo experiencias prácticas más enriquecedoras, incorporando de manera innovadora la tecnología en el proceso enseñanza/aprendizaje con vectores. Las aportaciones de la propuesta en el Front-end se basa en el modelo de componentes con las siguientes ventajas: conquista de la complejidad, manejo del cambio, y maximiza la reutilización de las partes del proyecto. La utilización de patrones de software ha permitido mejorar la arquitectura de la propuesta mejorando: composición, escalabilidad, maximización de la reutilización y mantenibilidad. El CRUD de la propuesta ha posibilitado la elaboración de ejercicios multimedia interactivos, reconfigurables y dinámicos.
Evaluación de la incidencia de la geometría del área de reflexión en el rendimiento óptico de un prototipo artesanal de concentrador cilindro-parabólico
Authors: Tarazona-Romero Brayan Eduardo , Ascanio-Villabona Javier Gonzalo , Sandoval-Rodriguez Camilo Leonardo , Rincón-Quintero Arly Darío
Published: January 2024

Este artículo tiene como objeto evaluar la incidencia de la geometría del área de reflexión en el rendimiento óptico de un sistema a baja escala de concentrados cilindro-parabólico. El sistema fue desarrollado y probado para calentar agua o generar vapor de agua en las Unidades Tecnológicas de Santander, ubicadas en Bucaramanga, Colombia. Se tuvieron en cuenta factores ópticos del prototipo real para realizar un análisis de trazado de rayos de monte Carlo, aplicando la Herramienta SolTrace. El sistema de concentración real, fue sometido a una comparación con dos sistemas geométricamente diferentes, es decir, un concentrador con dimensiones inferiores al sistema real y uno con dimensiones mayores, con el fin de determinar los rendimientos ópticos y las relaciones de concentración, para determinar la relación existente entre estos dos parámetros y el rendimiento de la unidad. Los resultados obtenidos, mostraron que el área de reflexión afecta directamente el rendimiento óptico y la relación de concentración del dispositivo, evidenciando que, a mayor área de concentración, mayor rendimiento del equipo.
Truck Chassis Design and Analysis
Authors: De Aguiar João Batista , De Aguiar José Manoel
Published: January 2024

Commercial trucks of medium size are nowadays object of redesign of their structural system in the intent of increasing size or load capacity. The chassis is an essential element in this task. Many times, while keeping the front and rear overhangs of the chassis fixed, the inter-wheel distance is increased, sometimes with inclusion of an additional shaft, to allow that larger load containers with more capacity be used. Reconfigured geometrically, it has to support static and dynamic loads. In this sense a model of the ladder type chassis, post initial design, is submitted to alterations. Geometry, materials and loading are considered in a design method for hyperstatic conditions. Response of the model, using the finite element method, is presented to characterize diverse loadings. A set of critical sections is observed. Based upon the obtained results, the adequacy of the implemented method is verified.
Investigación científica sobre tecnologías empleadas en quemadores de biomasa tipo pellets a pequeña escala, como potencial energético alternativo: una revisión bibliométrica
Authors: Rincón-Quintero Arly Darío , Del Portillo-Valdés Luis Alfonso , Lengerke-Perez Omar , Rondón-Romero Wilmar Leonardo , Sandoval-Rodriguez Camilo Leonardo , Tarazona-Romero Brayan Eduardo
Published: January 2024

La investigación se centra en la implementación de un software de visualización de redes bibliométrica denominada VOSviewer, donde se procesan los registros obtenidos en la literatura científica, identificando los recientes avances en calderas de biomasa (caso de estudio: pellets) a pequeña escala, aplicando una metodología en análisis de redes y vigilancia de bases de datos, desarrollando redes con palabras clave, coautoría y acoplamiento bibliográfico, graficas que permiten visualizar las tendencias y resaltan el comportamiento de la comunidad académica sobre una determinada temática. Los autores con mayor relevancia, recomiendan la adición de caolín en biomasas, pudiéndose disminuir las emisiones contaminantes. También, destacan la implementación de tecnologías que controlen el flujo de aire primario y secundario en la combustión, repercutiendo en una mejora en la eficiencia, todo esto, con la extracción continua de cenizas sin tener que detener o afectar el proceso de combustión y el uso de filtros para material particulado.
Evaluación numérica a la fatiga de prótesis tumoral de rodilla
Authors: de la Mora-Ramírez Tomas , Coutiño-Moreno Elvis , Maldonado-Onofre Daniel , Aparicio-Urbano José
Published: January 2024

En los últimos años, el rendimiento mecánico de polietileno de ultra alto peso molecular (UHMWPE) ha atraído una gran cantidad de interés en aplicaciones de prótesis articulares. La importancia clínica de la fatiga y las propiedades a la fractura de las piezas fabricadas con UHMWPE depende del dispositivo protésico. Los mecanismos de desgaste abrasivo y adhesivo usualmente prevalecen en los insertos acetabulares recuperados, observando que las superficies dañadas por fatiga se presentan a menudo en insertos tibiales. Por lo tanto, la resistencia al desgaste es de gran importancia en los componentes protésicos, ya que a mayores presiones de contacto de la articulación hacen que las propiedades de fatiga y fractura sean más relevantes. Se puede concluir así que las formulaciones de grado médico del UHMWPE deben representar un equilibrio entre las consideraciones de diseño, resistencia al desgaste, resistencia a la oxidación, propiedades de fatiga y a la fractura. Por lo que una de las principales consideraciones para el diseño de algún dispositivo con cargas variables es el diseño por fatiga, evitando grietas a nivel micro, macro y como consecuencia falla súbita del sistema. Provocando como consecuencia un reemplazamiento total de la pieza o en el peor de los casos catástrofes donde se involucra vidas humanas. El objetivo de la presente investigación es proporcionar un análisis de fatiga y fractura, a través de una evaluación numérica a los bujes de material de UHMWPE utilizados en la articulación de la prótesis de rodilla. Se realizó un estudio de fatiga a la pieza buje tomando en consideración una posición en cuclillas de 130 grados de flexión del fémur con respecto a la tibia, mostrando resultados de la localización en donde inicia el daño en el buje, así como su tiempo de vida en años. Los resultados indican un ciclo de vida de 15.8 años antes de llegar a la falla del material.
Análisis de sistema de potencia para computadora de vuelo de un nano satélite CubeSat utilizando COTS
Authors: Eulopa-Hernandez Jhonatan Fernando , Gallardo-Mercado Hector Giovany , Padilla-Pérez Diego Alfredo
Published: January 2024

Los dispositivos CubeSats se concibieron con uno de los objetivos de proporcionar a los estudiantes experiencias en el diseño, construcción y pruebas aeroespaciales a escalas reducidas. Debido a esto, los CubeSats poseen ventajas competitivas en comparación con otros satélites; enfatizando el costo, flexibilidad y uso de productos comerciales listos para utilizar (COTS). Asimismo, la placa de potencia de estos dispositivos juega un papel crucial en el sistema de energía, ya que se encarga de distribuir la energía eléctrica para cada uno de los componentes del satélite, de manera segura y eficiente. No obstante, el uso de electrónicos no diseñados para misiones espaciales suele comprometer el rendimiento y confiabilidad de nuestro dispositivo. Por tanto, el análisis de la placa PCB es de suma importancia para garantizar el correcto funcionamiento del CubeSat, salvaguardando su integridad y los subsistemas dependientes. Este documento plantea el análisis de una placa de potencia para la computadora de vuelo, empleando sistemas redundantes, de control y registro de fallos, así como el uso de componentes COTS para su implementación, adaptación y alcance en cualquier entorno industrial, educativo y comercial; con la finalidad de redituar mayormente el funcionamiento del dispositivo.