bluuebunny/crossref_metadata_2025 huggingface dataset:
Morphological and Histological Studies of Artesunate on the Developing Cerebral Cortex of Wistar Rat Foetuses
Authors:   Department of Human Anatomy, Faculty of Basic Medicine, Ahmadu Bello University, Zaria, Nigeria, Samuel Emmanuel , Ivang Andrew ,   Department of Human Anatomy, Faculty of Basic Medicine, Ahmadu Bello University, Zaria, Nigeria, Ibegbu Augustine ,   Department of Human Anatomy, Faculty of Basic Medicine, Ahmadu Bello University, Zaria, Nigeria
Published: December 2023

The longstanding use of artemisinin and its derivatives, mainly artesunate among pregnant women is recommended as first line treatment for malaria especially in endemic area like Nigeria. The present study investigated the morphological and histological effects of artesunate on the developing cerebral cortex of Wistar rat foetuses. Twenty healthy female Albino Wistar rats of average weight of 165 g were grouped into 4 with each group containing 5 rats. The rats were fed daily and water was allowed ad libitum. The animals were mated overnight with sexually matured males and were separated into different cages after confirmation of pregnancy. Oral doses of 0.2 mg/kg (low dose, LD), 0.4 mg/kg (medium dose, MD) and 0.8 mg/kg (high dose, HD) body weight of artesunate were administered to pregnant rats in LD, MD and HD groups respectively, from the 8th to the 12th day of gestation. Group 1 rats were the control, and received distilled water on the same days. The results showed a significant reduction in the morphometry of some body parts. The mean foetal body weights were 5.33 g, 5.14 g, 4.67 g and 3.78 g in the Control, LD, MD and HD groups respectively, while the mean crown-rump lengths were 3.67 cm, 3.43 cm, 3.00 cm and 3.00 cm in the Control, LD, MD and HD groups respectively. The histological examinations revealed some neurodegenerative changes in the developing cerebral cortex of Wistar rat foetuses. These neurodegenerative changes include reduction in thickness of the cortical zones, cell clustering and chromatolysis of the cells of cerebral cortex. The results showed that artesunate when administered in high dosages could be dangerous to the developing foetuses
Responses to Aqueous Leaf Extract of Luffa aegyptiaca Mill on Mefloquine-Induced Seizure in Rat Using Open Field Test
Authors:   Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Science, University of Port Harcourt, Choba, Nigeria, David Lekpa , Fawehinmi Hakeem ,   Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Science, University of Port Harcourt, Choba, Nigeria, Ihunwo Amadi ,   Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Science, University of Port Harcourt, Choba, Nigeria,   School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Published: December 2023

Neuro-behavioural responses to Luffa aergyptiaca mill on mefloquine-induced seizure was investigated in rats. Twenty five male Wistar rats (190-250 g) were assigned into 5 groups with five rats per group, namely; control group, mefloquine group only (seizure, 4.28 mg/kg), mefloquine and then diazepam (seizure + diazepam, 5 ml/kg), mefloquine and then low dose Luffa aergyptiaca mill group (seizure + low dose Luffa, 400 mg/kg), and mefloquine and then high dose of extract (seizure + high dose Luffa, 1200 mg/kg). Doses of mefloquine and luffa extract were administered to the rats according to their body weight. After thirty (30) minutes of administration, each rat was placed subsequently in the centre platform of the open field and then observed for five (5) minutes. Line crossing, central square entry, central square duration, stretch attends posture, number of faecal droppings, urination, grooming, and frequency of rearing were recorded with a video camera. Precaution was taken to ensure that no external stimulus evoked anxiety in the rat. Line crossing and rearing were significantly lower in the MFQ group than those of the control and other treated groups. No significance difference was observed between control and treated groups for centre square entry, centre square duration and grooming. There was significant difference for stretch attend posture, freezing time, urination and defecation between control and other groups. Increased line crossing shows anxiety reduction in the open field. Hence these results do suggest that aqueous extract of leaf of Luffa aergyptiaca mill can revoke anxiety in rats.
Pleurotus tuber Regium: Ethanolic Extract Improves Spatial Learning and Memory in Rats but Alters Cerebral Cytology
Authors:   Department of Anatomy, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria, Akpantah Amabe , Chimdindu Emeka-Emeh Chimdindu,Emeka-Emeh ,   Department of Anatomy, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria, Eluwa Mokutima ,   Department of Anatomy, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria, Udonkang Mfoniso ,   Department of Medical laboratory Sciences, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria, Isamoh Theresa ,   Department of Anatomy, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria, Igiri Anozeng ,   Department of Anatomy, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria
Published: December 2023

This work was carried out to determine possible toxic effects of Pleurotus tuber regium (an edible fungus) on the histology of the cerebral cortex (prefrontal cortex), spatial learning and memory in rats after its consumption. Twenty one adult Wistar rats weighing 150-200g were used. The animals were randomly divided into three groups: control, low and high test groups. The control group received distilled water while the test groups received 25mg/kg and 50mg/kg of the ethanolic extracts of Pleurotus tuber regium as 0.5 ml and 1ml for the low and high doses, respectively. Administration was done orally with the aid of orogastric tube for 4 weeks. The tests for visuo spatial learning and memory were carried out concurrently with the administration. The animals were sacrificed 24 hours after the last administration after being anaesthesized with diethyl ether. The brains were preserved in bufferred formaldehyde, and were processed and stained with haematoxylin and eosin method. Results showed dose dependent atrophy in the cells of the cerebrum. The swim latency and quadrant duration were significantly higher (p < 0.05) in the 50 mg/kg group (high dose group) implying that the extract had a dose dependent enhancing effect on learning and memory. In conclusion, the extract of Pleurotus tuber regium improved learning and memory in rats but presented untoward effect at a higher dose.
Impaired Cognitive Performance and Metabolic Disturbance in Streptozotocin-Nicotinamide Induced Type 2 Diabetes Mellitus and the Protective Effect of Nigerian Propolis
Authors: Amin Abdulbasit , Saliu Halima , Solomon Emmanuel , Shehu Tajudeen , Imam Aminu , Abdulmajeed Wahab , Alli-Oluwafuyi Abdulmusawwir , Ibrahim Ridwan , Owoyele Bamidele
Published: December 2023

Defects in insulin signaling and oxidative stress are implicated in cognitive dysfunction in diabetes. This study evaluated the effects of propolis on cognitive impairment in streptozotocin-nicotinamide model of type 2 diabetes mellitus in Wistar rats. Diabetes was induced by single intraperitonieal administration of streptozotocin (65 mg/kg) 15 min after nicotinamide (110 mg/kg) had been adminstered. Diabetic animals were treated with glibenclamide (5 mg/kg), propolis (200 and 300 mg/kg), or normal saline for 4 weeks after which spatial memory was assessed with the Morris’ water maze (MWM). At the end of the study the animals were euthanized and blood collected via cardiac puncture while the brain was homogenized. Insulin was assayed from plasma while malondialdehyde (MDA), superoxide dismutase (SOD), gluthatione (GSH) and catalase were assayed from brain homogenate. Homeostatic model assessment (HOMA) was used as marker for insulin resistance. Significant rise in blood glucose, plasma insulin, and brain MDA (P < 0.05) with reduction in SOD, GSH, and catalase levels were observed in the diabetic group. Treatment with 200 and 300 mg/kg propolis and glibenclamide significantly decreased blood glucose, plasma insulin, and MDA (P < 0.05) and increased brain levels of SOD, GSH and catalase. Propolis (200 and 300 mg/kg) also significantly (P < 0.05) decreased escape latency in the MWM in comparison to the diabetic group. Nigerian propolis thus seems to protect against impaired cognitive performance in experimental diabetes mellitus.
A Review on Air Pollution and a Link with Neurodegenerative Diseases in Nigeria
Authors:   Department of Anatomy, Faculty of Basic Medical Sciences, Nile University of Nigeria, Abuja, Nigeria, Ajagbe Abayomi , Onigbinde Oluwanisola ,   Department of Anatomy, Faculty of Basic Medical Sciences, Nile University of Nigeria, Abuja, Nigeria, Ajiboye Ebenezer ,   Department of Physiology & Anatomy, Ajayi Crowther University, Oyo, Nigeria, Ajenikoko Michael ,   School of Biomedical Sciences, Kent State University, Ohio, United States of America, Shittu Lukeman ,   Department of Research and Development, Jireh Laboratories International LLC, Alief, Texas, United State of America, Dabi Yosef ,   Department of Medical Laboratory Science, Wollega University, Ethiopia, Usende Ifukibot ,   Department of Veterinary Anatomy, Faculty of Veterinary Medicine, University of Abuja, Abuja,  Nigeria
Published: December 2023

Pollution is a common and inevitable situation, encompassing environmental threats and virulent composites from the air, water, soil, and food. Air pollution is becoming a global health challenge, affecting millions of lives. Although many of these pollutants have been identified, this paper is reviewing the established link between air pollution and neurodegenerative disease due to the increase in cases of neurodegenerative disease in middle- and low-income countries like Nigeria. This article reviewed the establishment of a possible relationship between air pollution and neurodegenerative diseases in Nigeria and Africa. Different literature sources were reviewed to identify the sources of air pollution, determine the level of awareness among citizens on the effects of air pollution, know the incidence of neurodegenerative diseases in air-polluted areas, life expectancy in such areas, existing diseases caused by air pollution, and their relationship with neurodegenerative diseases. Available literature on heavy metal pollutants in the brains of animal models from different zones of Nigeria and evidence of neurodegeneration in different animal species was also reviewed. In conclusion, one major setback is that there is no specific data on the prevalence of neurodegenerative diseases in major air-polluted areas in Nigeria, hence, the need for awareness to alert occupants and citizens to neurodegenerative diseases and their connection with air pollution. It is also advised that the government implement steps to solve these difficulties, such as the employment of biodegradation and bioremediation in the removal of contaminants.
Immunohistochemical Investigations of the Thalamic Region in Rats Following Combined Exposure to Metals and Restraint Stress
Authors:   Department of Human Anatomy, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria, Anadu Victor ,   Laboratory for Experimental and Translational Neurobiology, University of Medical Sciences, Ondo, Nigeria, Okeowo Oritoke ,   Department of Physiology, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria,   Laboratory for Experimental and Translational Neurobiology, University of Medical Sciences, Ondo, Nigeria, Adejuwon Joy ,   Department of Human Anatomy, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria, Akinola Olamide ,   Department of Human Anatomy, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria, Akinnagbe Endurance ,   Department of Human Anatomy, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria, Ijomone Omamuyovwi ,   Department of Human Anatomy, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria,   Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA,   Laboratory for Experimental and Translational Neurobiology, University of Medical Sciences, Ondo, Nigeria
Published: December 2023

Chronic exposure to stress has been linked to the perturbation of normal brain functioning. Further, metal overexposure due to their increasing applications can negatively impact brain health. Combined exposure to stressful events and metals is common but has not yet been studied. Thus, this study focused on the thalamic region for its role as a vital relay station in the brain to investigate apoptotic and microglia activation, oxidative stress regulation, and myelin damage following co-exposures to restraint stress and metals, manganese (Mn) and nickel (Ni). Thirty-six adult male rats were divided into six groups and, respectively, exposed to the following for 15 days: control group (normal saline), stress group (3 hours of restraint stress daily), Mn and Ni only groups (intraperitoneal injection of 25 mg/kg of metals), and stress + metal groups received Mn or Ni prior to being subjected to restraint stress. Following treatments, immunohistochemical procedures were used to evaluate relevant neurochemical markers. Results show significantly increased activation of caspase-3 in stressed, metal-only, and combined stress-plus-metal treatments, particularly with Mn treatments. Also, the results show a varying response to Iba1, the microglia activation marker. Furthermore, the study reports significant decreases in Nrf2 (nuclear factor erythroid 2-related factor 2) expression that is potentiated by combined stress and metal treatments as well as altered myelination-linked proteins, Olig2 (oligodendrocyte lineage transcription factor 2), and MBP (myelin basic protein). Overall, the result from this study indicates that the combination of stress and metal exposure could exacerbate the neurotoxic impact of metal toxicity or stressful events.
Impact of Macroeconomic Factors on Stock Market: Empirical Evidence from the Philippines
Authors: John E. Endres Erick
Published: December 2023

The study analyzes the short and long-run relationship between the Philippine Stock Exchange Index and macroeconomic variables industrial production rate, inflation rate, interest rate and foreign exchange rate. In particular, the paper examines secondary data from January 2009 to December 2019 with the use of Autoregressive Distributed Lag (ARDL) to estimate causality function; F-Bounds Test and Wald Test to confirm long-run relationship; and Error Correction Term (ECT) to determine the adjustment of short-run errors towards long-run equilibrium. The results show that industrial production rate and interest rate have a significant negative long-run and positive short-run relationship, respectively, while the foreign exchange rate has both significant positive short-run and negative long-run correlation with the stock market.
The Influence of E-Wom and Digital Marketing on Purchasing Decisions at Shopee Marketplace in Palembang City
Authors: Changreani Evelyn , Manalu Anggriani Boru , Purb Rizki Fatricia , Putri Destriana
Published: December 2023

The purpose of this study was to analyze the influence of Electronic Word of Mouth (E-WOM) and Digital Marketing on purchase decisions made by consumers on the Shopee marketplace, especially in Palembang City. The use of E-WOM and Digital Marketing has increased significantly with the development of social media and e-commerce. The research method used was a causality approach with quantitative data collected from 100 Shopee application users in Palembang City through an online questionnaire. The research results showed that E-WOM and Digital Marketing significantly influenced the purchasing decisions made on the Shopee marketplace. Every improvement in online reviews (E-WOM) regarding Shopee led to an increase in purchase decisions. Additionally, an effective Digital Marketing strategy also contributed positively to consumer purchase decisions. The use of technology and online media, particularly related to the Shopee marketplace, was recognized as an important factor in consumer behavior. This study helps to understand the importance of E-WOM and Digital Marketing in online marketing, with a focus on consumers in the city of Palembang. The practical implications of this study are that companies can improve their digital marketing strategies and manage online reviews effectively to positively influence consumer purchase decisions.
Analisis Faktor Supply Tenaga Kerja Terdidik Lulusan Universitas Muhammadiyah Yogyakarta
Authors: Arindra Lutfiah Putri , Dewanti Diah Setyawati
Published: December 2023

Pendidikan adalah modal utama masyarakat untuk dapat bersaing dalam dunia pekerjaan dan diharapkan dengan tingginya pendidikan yang dimiliki oleh seorang individu dapat berpengaruh kedalam produktifitas kerja individu itu sendiri. Hal ini akan menjadikan seorang individu lebih siap latih dalam melakukan pekerjaan yang akan memacu tingkat produktifitas tenaga kerja. Penelitian ini bertujuan untuk menganalisis supply tenaga kerja terdidik lulusan Universitas Muhammadiyah Yogyakarta. Variabel yang digunakan dalam penelitian ini yaitu variabel IPK, lama studi, jenis kelamin, tingkat perusahaan dan gaji sebagai variabel independen dan lama mencari pekerjaan merupakan variabel dependen. Penelitian ini menggunakan analisis Unvariat dan Bivariat dengan bantuan alat analisis SPSS versi 25.00. Hasil penelitian ini menunjukkan bahwa IPK, lama studi dan gaji memiliki hubungan dengan lama mencari pekerjaan lulusan Universitas Muhammadiyah Yogyakarta, sedangkan jenis kelamin dan tingkat perusahaan tidak memiliki hubungan dengan lama mencari pekerjaan lulusan Universitas Muhammadiyah Yogyakarta.
Analisis Faktor Ekonomi, Sosial, Lingkungan dan Kelembagaan Terhadap Kesejahteraan Pedagang Kaki Lima Malioboro Pasca Relokasi di Teras Malioboro 1
Authors: Pratama Panggih Abdi , Wardani Dyah Titis Kusuma
Published: December 2023

Penelitian ini dibuat untuk mengetahui kondisi Kesejahteraan yang dialami oleh pedagang kaki lima Malioboro pasca relokasi di Teras Malioboro 1. Penelitian ini menggunakan metode probability sampling dengan cara stratified random sampling. Jumlah sampel yang digunakan pada penelitian ini sebanyak 254 responden. Metode yang digunakan untuk mengumpulkan data yaitu angket kuisioner yang terdiri dari Variabel Kesejahteraan, Ekonomi, Sosial, Lingkungan, dan Kelembagaan. Pengambilan data responden penelitian dilakukan dengan cara turun langsung ke lapangan dan menyebar kuisioner dengan instrumen penelitian menggunakan skala likert. Hasil penelitian ini menjelaskan bahwa (1) Faktor Ekonomi berpengaruh positif dan signifikan terhadap Kesejahteraan pedagang kaki lima Teras Malioboro 1 pasca relokasi.. (2) Faktor Sosial berpengaruh positif dan signifikan terhadap Kesejahteraan pedagang kaki lima Teras Malioboro 1 pasca relokasi. (3) Faktor Lingkungan berpengaruh positif dan signifikan terhadap Kesejahteraan pedagang kaki lima Teras Malioboro 1 pasca relokasi. (4) Faktor Kelembagaan berpengaruh positif dan signifikan terhadap Kesejahteraan pedagang kaki lima Teras Malioboro 1 pasca relokasi. (5) secara parsial dan simultan seluruh Variabel Ekonomi, Sosial, Lingkungan, dan Kelembagaan berpengaruh positif terhadap Kesejahteraan pedagang kaki lima pasca relokasi.
Determinan Ketimpangan Pendapatan di Seluruh Provinsi di Sumatera
Authors: Julihanza Agra , Khoirudin Rifki
Published: December 2023

Penelitian ini bertujuan untuk mengetahui pengaruh pertumbuhan ekonomi, jumlah penduduk, upah minimum, inflasi, investasi terhadap ketimpangan pendapatan antara Provinsi di Sumatera mengunakan data tahun 2015-2021. Metode analisis data yang digunakan adalah analisis regresi data panel. Hasil penelitian menemukan bahwa pertumbuhan ekonomi dan investasi memiliki pengaruh negative tidak signifikan terhadap ketimpangan pendapatan, jumlah penduduk dan investasi memiliki pengaruh positif dan tidak signifikan terhadap ketimpangan pendapatan, dan upah minimum memiliki pengaruh negative signifikan terhadap ketimpangan pendapatan antara Provinsi di Sumatera. Secara Bersama-sama pertumbuhan ekonomi, jumlah penduduk, upah minimum, inflasi, investasi berpengaruh signifikan terhadap ketimpangan pendapatan.

 

This research aims to determine the effect of economic growth, population, minimum wage, inflation, investment on income inequality between provinces in Sumatra using data from 2015-2021. The data analysis method used is panel data regression analysis. The research results found that economic growth and investment had an insignificant negative influence on income inequality, population and investment had a positive and insignificant influence on income inequality, and the minimum wage had a significant negative influence on income inequality between provinces in Sumatra. Together, economic growth, population, minimum wage, inflation, investment have a significant effect on income inequality.
Pengembangan Website ‘BALASAN’ Sebagai Upaya Peningkatan Minat Belajar Bahasa Isyarat Indonesia
Authors: Ramadhan Fija , Fatiha Luthfia Jayyida Ainaya , Krisanti Haeranisa Bella , Rozan Daffa , Z Caezario Rafie Anggara
Published: December 2023

This website development uses fun and interactive methods. This website collaborates with GERKATIN which provides Bisindo classes which discuss understanding the world of the Deaf, how to communicate with the Deaf, and learning the basics of Indonesian Sign Language to build inclusive communication relationships. In this web development, there are 3 Bisindo service options that can be chosen according to your needs. One of the services is the Bisindo class, where we can take direct (face to face) classes accompanied by experienced Deaf teachers. To be able to take this class you can choose a level, namely level 1 & 2. The class schedule starts when the class quota has been met. Each class is held 10 times according to the schedule determined by GERKATIN.
Peningkatan Permohonan Dispensasi Perkawinan (Dini) di Pengadilan Agama Akibat dari Perubahan Sosial
Authors: Safira Amanda Aurelia , Pratiwi Amalia Mega , Melan Melan , Saputra Stanislaus Michel
Published: December 2023

Marriage is a sacred bond that unites two individuals with the support of society and religious organizations. However, in the ever-changing social dynamics, the phenomenon of early child marriage has become a big problem in Indonesia. This article examines the increase in marriage applications in Religious Courts as a result of social changes that conflict with the rights of children and adults. Law Number 16 of 2019 concerning Amendments to Law Number 1 of 1974 concerning Marriage sets the minimum age limit for marriage. This change has a significant impact on children's basic rights as well as their physical and psychological development. The author also examines the impact of implementing the revised minimum age for marriage policy in 2019 on the rate of child marriage in Indonesia. The research method we use is a normative legal approach in terms of methodology. By considering these issues, this research provides an in-depth understanding of the challenges facing the marriage system in Indonesia as well as the social and regulatory changes that may impact efforts to overcome these challenges.
Proposed Value Proposition and Business Model for VMCS Advisory Indonesia
Authors:   School of Business Management, Institut Teknologi Bandung, Makki Elvera Nuriawati
Published: December 2023

The development of the business world and leadership in various industries depends on critical factors, including the role of corporate communications and public relations. Since the beginning of civilization, communication has facilitated the development of relationships between people and institutions, increasing reputation and spreading knowledge. With the advancement of the digital world, strategic communication has become increasingly important for managing reputation, both personally and institutionally. In a democratic climate and era of openness, strategic communication becomes more critical and must align with the mission, vision, and business goals. Various challenges arise, especially in formulating communication strategies, handling management issues and crises, coordinating between functions, and implementing communication campaigns; hence, external communication experts are needed to help nurture a company’s relationship with its stakeholders. This opportunity becomes the basis for establishing a communications and social impact consultant, PT Viem Advisory Indonesia (VMCS, abbreviation of Vera Makki Communications and Social Impact), in 2020. This study aims to formulate a value proposition, followed by proposing a business model that supports the value proposition and uses a qualitative descriptive analysis that takes data from interviews with representatives of communications industry experts, academicians, business leaders, and media. In addition, secondary data collection was also carried out, supported by a review of academic literature, basic theory, and conceptual frameworks, which systematically guided the start of a business in the communication and social impact consulting field. With this foundation, this study describes the business analysis, solutions, and recommendations to build VMCS with the right value proposition and business model. This study is designed so that VMCS can become a leader in the communications industry, with the uniqueness of not only focusing on profits in the business world but also prioritizing social impact and sustainability.
The Impact of Perceived Value and Attitude towards Purchase Intention at Sambel Branding Restaurant
Authors:   Institut Teknologi Bandung, Indonesia, Debora Rima , Aprianingsih Atik ,   Institut Teknologi Bandung, Indonesia
Published: December 2023

Sambal is a traditional Indonesian spice that has been an essential component of Indonesian cuisine for centuries. Today, it is considered a staple spice in all Indonesian dishes. The popularity of sambal has attracted many new restaurants of varying scales to enter the spicy food market and utilize the “Sambel” brand as their restaurant attraction. Jakarta, which is one of the eight primary cities in Indonesia, ranks fourth with the most restaurant dine-in visits in 2022. As per the data provided by the Central Statistics Agency (BPS), there are 6,780 restaurant units in Indonesia of medium to large scale. Jakarta secures the top spot as the province with the most medium-scale restaurants in Indonesia, with 3,062 units in 2021. Sambel Korek DNO is one of the dining places in Jakarta with the Sambel, the central outlet is located in Sumur Batu Kemayoran. This establishment is the highest contributor to the sales of Sambel Korek DNO as compared to other establishments. The significant consumption levels of Jakartans and their fondness for spicy cuisine drive new entries to launch their street food stalls, small establishments, and restaurants under the Sambel brand, causing an increase in competition. However, the sales of DNO Korek Sambal did not meet the target this year due to a decline in the number of customers dining at this outlet. This could be attributed to low brand awareness, as many other eateries also use the “Sambel” branding. Additionally, customers’ perception of quality may be influenced by the similarity in offerings with other major players in the “Sambel” market, such as Waroeng SS and Sambal Bakar Indonesia. This research wants to analyze whether perceived value and attitude could mediate brand awareness and perceived quality toward purchase intention for potential customers and existing customers. This research is conducted using SPSS and PLS-SEM. Resulting that Attitude has no mediating effects on brand awareness and perceived quality towards purchase intention. However, perceived quality has mediating effects on brand awareness and perceived quality towards attitude, which has a significant influence on purchase intention.
Implementation Strategy “3R CIRCULAR ECONOMY” To Achieve SDG Target 11.6 “Municipal Waste Management” In Cipaganti Village, Bandung City (Study at the Cihampelas Mandiri Unit Garbage Bank)
Authors:   School of Economics and Business, Telkom University, Indonesia, Nurrochman Miftah Meinaldi , Lubis Ratna Lindawati ,   School of Economics and Business, Telkom University, Indonesia
Published: December 2023

Good municipal waste management is very important for a sustainable urban order. Good municipal waste management can reduce negative impacts on the environment, public health and natural resources. The application of a Garbage Bank is one of the solutions for good municipal waste management. This is due to the concept of a Garbage Bank which is aligned with sustainable city management. One of the principles that is effective in helping the performance of waste management at the Garbage Bank is a circular economy based on 3R (reduce, reuse, and recycle). The application of this concept needs to be supported by campaigns involving various activities such as outreach, education, training and promotion which aim to increase public awareness about the importance of sustainable waste management. This study aims to examine the Garbage Bank campaign strategy as an effort to support the achievement of Target 11.6 of the Sustainable Development Goals (SDG), namely “Urban Waste Management”, by implementing a 3R-based circular economy approach in Cipaganti Village, Bandung City. This study uses a qualitative approach with a case study method of a Garbage Bank in Cipaganti Village, Bandung City. Data was collected through in-depth interviews, participatory observation, and analysis of related documents. The key informants in this study were community members, related stakeholders, and the management of the Waste Bank in Cipaganti Village. The results of this study are expected to provide a better understanding of the effectiveness of the Garbage Bank campaign strategy in realizing SDG Target 11.6 in Cipaganti Village, Bandung City, as well as provide guidance for the government and related organizations in planning and implementing sustainable waste management activitiesgovernment and related organizations in planning and implementing sustainable waste management activities.
Applying an Analytical Hierarchy Process for Decision Making Business Strategy in CV. Optik President
Authors:   Master of Business Administration, School of Business & Management, Bandung Institute of Technology, Fernando Niko , Sarjono Putro Utomo ,   Master of Business Administration, School of Business & Management, Bandung Institute of Technology
Published: December 2023

Vision is one of the vital organs of the human body which has a very fundamental role for life. With good eyesight, this can help people improve their quality of life. The eyeglass market is anticipated to develop over the next several years as a result of a variety of factors, including expanding populations, a demographic shift toward older age groups, and changing lifestyles characterized by a higher reliance on digital gadgets. Of course, the COVID-19 pandemic is also one of the factors that increases eye disease because most people use gadgets in their lives, causing symptoms of digital eye strain. In this way, this is a supporting factor in the development of the optical market. The market is expanding the fastest in the Asia Pacific region, with a growth rate of 13.5%. Offline optical retail stores provide significant promise and value. These physical businesses provide customers with an immersive and tangible shopping experience that is unmatched by internet shopping. To guarantee that customers receive accurate prescriptions and distinctive eyewear options, optometrists and store staff offer customized services like frame fittings, professional eye exams, and expert lens consultations. In actual storefronts, customers may physically try on frames to assess fit, comfort, and style. Trained staff members are available to provide timely assistance. Furthermore, a wide range of eyewear options, including designer brands and niche goods, are usually available in these stores, giving customers the opportunity to peruse and select from a diverse inventory. Furthermore, optical retail stores foster confidence and trust, particularly among those who appreciate in-person interactions or have certain vision needs that necessitate expert guidance. By looking at this market development, the company wants to expand, targeting West Karawang, East Karawang and Cikarang as targets for opening their branches. using the Analytical Hierarchy Process (AHP) method will be able to improve the quality of decision making that will be produced by the company starting from developing criteria and sub-criteria which can ultimately determine the best alternative. The results of this research provide recommendations for new criteria and sub-criteria for the company and also determine which location of the three alternatives the company will provide.
Stock Valuation and Dividend Policy Decision of PT ELSA INDONESIA, TBK
Authors:   School of Business and Management, Bandung Institute of Technology, Utomo Muhammad Rizki , Damayanti Sylviana Maya ,   School of Business and Management, Bandung Institute of Technology, Noveria Ana ,   School of Business and Management, Bandung Institute of Technology
Published: December 2023

Oil shortages began in 2015 due to underinvestment caused by ESG policy. Oil firms need the funds to finance their new refinery, rig, and exploration since most western countries are switching from oil to alternative energy. Geopolitical and economic instability, fear of a downturn, and rising inflation have harmed the worldwide Oil and Gas services market Since Russia invaded Ukraine in 2022, oil prices rose to USD122/barrel for WTI and USD128/barrel for Brent. WTI fell to USD80/barrel and Brent to USD86/barrel by 2022, despite mid-year volatility. PT Elnusa Tbk is an integrated oil services company through its subsidiaries, offers services that include geophysical data, drilling, and oilfield services. The objective of this research is proposes to evaluate the financial performance, valuation and making a recommendation for ELSA regarding its cash. Two methods of valuation are utilized to estimate ELSA’s intrinsic value: absolute valuation and relative valuation. Discounted Cash Flow to the Firm (DCF) model is used for absolute valuation, meanwhile Price to Book Value (PBV) and Price to Earning Ratio (P/E Ratio) methods are used for relative valuation. Dividend policy and buyback share projection is conducted to find the best decision for ELSA. By referring to absolute valuation, ELSA’s intrinsic value is estimated at IDR639/share. By referring to relative valuation using PBV and P/E methods, ELSA’s intrinsic value is calculated at IDR 564/share . These numbers are significantly higher than ELSA’s current price at IDR 378/share, thus providing relatively high margin of safety.in the following stage ELSA will keep on paying dividends to the shareholders. With ELSA DPR 33,25% in 10 years ELSA will have 4,756,289 million in 10 years and the cash could be for management risk if a big crisis or force majeure.
Improving Market Strategy in E-Commerce Platform in Jakarta (Case Study of Steggo Frozen Meat Distributor)
Authors:   Master of Business Administration, School of Business and Management, Institut Teknologi Bandung, Jl. Ganesha No.10 Bandung 40132, Indonesia, Aditama Anugerah , Aprianingsih Atik ,   Master of Business Administration, School of Business and Management, Institut Teknologi Bandung, Jl. Ganesha No.10 Bandung 40132, Indonesia
Published: December 2023

In 2022, Indonesia anticipates a surge in e-commerce users, forecasted to hit 178.94 million from 158.65 million, indicating sustained growth. Projections foresee a rise to 196.47 million users by 2023, persisting for four years. STEGGO aims to leverage this trend, employing internal STP and Marketing Mix (4Ps) and external PESTEL, Competitor, and Customer Analyses. SEM-PLS will decipher insights from surveys, linking the marketing mix to customer attitude and purchase intention. Surprisingly, promotional efforts exhibit a negative correlation to customer attitude for STEGGO products. The analysis aims to guide STEGGO to target the right niche within the frozen meat distributor competition. Notably, product, price, and place significantly influence customer attitude, impacting purchase intentions by shaping customer acceptance for product re-purchase.
Business Model Innovation to Optimize Revenue Growth in the B2C Sector of Research Service Providing Institution: Case Study at Nano Riset Indonesia
Authors:   Master of Business Administration, School of Business and Management, Bandung Institute Technology, Akbar Naufal Bintang , Prasetio Eko Agus ,   Master of Business Administration, School of Business and Management, Bandung Institute Technology
Published: December 2023

This research explores business model innovation at Nano Riset Indonesia NRI, a leader in nanotechnology research, focusing on enhancing revenue growth in the Business-to-Consumer (B2C) sector. The thesis presents an in-depth narrative of NRI’s business model, critically examining its internal operations and external market environment. Employing a holistic methodology, it blends quantitative and qualitative analyses, utilizing frameworks like VRIO, Porter’s Five Forces, and the Business Model Canvas to evaluate NRI’s position and identify areas for innovation. Key focuses include improving consumer value propositions and strengthening customer relationships, all while maintaining cost efficiency. Central to the thesis is a strategic vision for a reimagined business model, tailored to the unique demands of the B2C market. This proposed model aims to financial improvement but also to cultivate a sustainable business growth and adaptability in the dynamic field of research services.
Quality Improvement for Sleeve Shirt X Using Lean Six Sigma Approach at PT X
Authors:   Universitas Katolik Parahyangan, Sutrisno Albertus N.
Published: December 2023

PT X, a key player in the garment industry, faces operational challenges, including inefficient motion in packing and product defects. Current state analysis reveals a lead time of 3,424.90 seconds, with a value-added time of 3,054.90 seconds. Direct observations attribute motion wastage during packing to suboptimal hand movements, stemming from inadequate training in motion time measurement. The future state map proposes packing process improvements through motion time measurement, reducing time from 87.27 to 86.32 seconds, with a lead time of 3,423.95. From January to December 2014, total production reached 239,359 units, with 30,702 defective products. The main defect, stitch breakage in short-sleeved shirts ‘X,’ occurred 15,386 times. Current process capability stands at 3.690 Sigma. Using the 5W+1H method, addressing the root cause of stitch breakage reduced defects to 15,316, with process capability improving to 3.952 Sigma, a 0.262 improvement. Post-improvement analysis estimates an added value in quality costs at Rp1,943,297,372. Lean Six Sigma implementation aims to minimize defects and lead times, enhancing profitability.
A FAMILY OF 82Q EXPONENTIAL HYBRID METHODS FOR SOLVING IVPS IN ODES
Authors:   Department Of Mathematics and Statistics, University of Port Harcourt, Rivers state,  Nigeria., M. Alex , F.E. Bazuaye ,   Department Of Mathematics and Statistics, University of Port Harcourt, Rivers state,  Nigeria.
Published: December 2023

In a recent paper, a new class of exponential general linear methods of second stage seventh order for the numerical solution of first order initial value problems in ordinary deferential equations was derived. In this paper, we derive the new class of higher order extended exponential general linear methods for the numerical solution of first order initial value problems in ordinary deferential equations. The numerical results obtained by the new method for some problems show its superiority in efficiency and accuracy for solving problems for which the proposed general linear method is appropriate
Sources and Levels of Natural Growth Promotants for Redbro Chicken
Authors:   Ilocos Sur Polytechnic State College, Ablog Mark Reagan B.
Published: December 2023

Fortification of animals’ diets with antibiotics in promoting the growth and development has increased the public’s concern about the safety of animal products and their adverse effects on human health and natural immunity. The study conducted at Mabilbila Sur, Santa, Ilocos Sur from January 12, 2021 to February 28, 2021. The study determined the best sources (garlic, oregano, turmeric) and levels (2g, 4g, 6g) of natural growth promotants and their interaction as an alternative to antibiotics. It aimed to determine the effects on the growth performance, carcass trait, sensory traits, and economic analysis of red broiler chicken. One hundred eighty (180) experimental birds were distributed into nine treatments (6 chicken/pen) including one floating control replicated thrice in a Strip-Split Plot Design. Supplementation of four grams turmeric infusion resulted to the heaviest chicken thus, higher profit above feed cost. Most efficient feed conversion attained with the supplementation of two grams garlic and oregano.
Effect of Serum Breadfruit Leaf Extract (Artocarpus Altilis) on TNF-Α and Sod Levels (Experimental Study on Guinea Pigs Exposed to UVB Light)
Authors:   Postgraduate student of Biomedical Sciences, Faculty of Medicine, Universitas Islam Sultan Agung, Jl Kaligawe KM 4 Semarang 50012, Winarni Nani , Harlisa Pasid ,   Department of Biomedical Sciences, Faculty of Medicine, Universitas Islam Sultan Agung, Jl Kaligawe KM 4 Semarang 50012, Subchan Prasetyowati ,   Department of Biomedical Sciences, Faculty of Medicine, Universitas Islam Sultan Agung, Jl Kaligawe KM 4 Semarang 50012
Published: December 2023

Continuous exposure to ultraviolet B (UVB) light can increase the amount of melanin, causing hyperpigmentation on the skin. This process involves the important role of Tumor Necrosis Factor-α (TNF-α) and Superoxide Dismutase (SOD). Artocarpus Altilis contain flavonoids that have anti-inflammatory potential, can reduce TNF-α levels and increase SOD which affects the melanogenesis process. To determine the effect of administering Artocarpus Altilis extract serum on TNF-α and SOD levels in guinea pigs exposed to UVB. This research is an in vivo experimental study with Post Test Only Group design, which was conducted at the IBL FK Laboratory (Integrated Biomedical Laboratory Faculty of Medicine) Unissula. A total of 30 male guinea pigs were divided into 5 groups, namely: Group 1 sham, group 2 negative control, group 3 treated with 2% Artocarpus Altilis extract serum, group 4 treated with 4% serum and group 5 treated with 6% serum. Then analyzed using the One-way ANOVA test to determine differences between groups. The lowest mean TNF-α levels were found in group P2 (4.958), other values were P1 (5.820), P3 (5.964), KS (6.069) and KN (5.811). Meanwhile, the average SOD levels in all groups were not much different, P2 (5.802), P1 (5.975), P3 (5.906), KS (6.054) and KN (6.000). In the One-way ANOVA test on TNF-α and SOD there was no significant difference, p>0.05. Administration Artocarpus Altilis extract serum, especially 4%, caused a decrease in TNF-α levels but was not significant, and there was no increase in SOD levels, in guinea pigs exposed to UVB light.
A Comprehensive Review of FACTS Controllers in Nigeria Power Systems Network for Enhanced Performance on Variable Loads
Authors:   Department of Instrumentation and Control, Total Energies Limited, Port Harcourt, Nigeria, Odion Joshua , Nelson Chukwu F. ,   Department of Electrical and Electronic Engineering, Akwa Ibom State University, Ikot Akpaden, Nigeria, B. Inyang Aniekan ,   Department of Electrical/Electronic, Akwa Ibom State Polytechnic, Ikot Osurua, Nigeria, Ekpa Andikan K. ,   Department of Electrical/Electronic, Akwa Ibom State Polytechnic, Ikot Osurua, Nigeria, Essien Uduak J. ,   Department of Electrical/Electronic, Akwa Ibom State Polytechnic, Ikot Osurua, Nigeria
Published: December 2023

Interest on FACTS controllers in the scientific and engineering community have increased due to their high reliability, low cost, and absence of infrastructural overhauling. In the context of global sustainability, it is required that FACTS controllers must fulfill physical, technological, and environmental requirements, through design and optimization studies. This study provides a comprehensive evaluation of the state-of-the-art technologies relevant to multi-objective optimization and performance analysis of FACTS controllers. Types, general overview, FACTS deployed in the Nigerian power systems and multi-objective location optimization and their impact were discussed. Several efficient optimization strategies from recent research works are highlighted and compared, showing that there are research gaps on the integration of advanced control algorithms and use of robust optimization methods.
Towards the Unification of Inheritance Law in Indonesia: Challenges and Opportunities in the Context of Religious and Cultural Diversity
Authors:   Fakultas Hukum, Universitas Prof. Dr. Hazairin., S.H., Bengkulu, Indonesia, Pratiwi Wiwit ,   Fakultas Hukum, Universitas Prof. Dr. Hazairin., S.H., Bengkulu, Indonesia, Fitri Sherly Nelsa ,   Fakultas Hukum, Universitas Prof. Dr. Hazairin., S.H., Bengkulu, Indonesia
Published: December 2023

This research examines inheritance law in Indonesia which is very pluralistic and not uniform, consisting of civil inheritance law regulated in the Burgerlijk Wetboek (WB), customary inheritance law regulated in their respective customary inheritance laws based on the existing kinship system (patrilineal, matrilineal, and parental), and Islamic inheritance law regulated in Islamic law. In heading towards the unification of inheritance law in Indonesia, there are challenges and opportunities that must be faced due to the diversity of religions and cultures that exist in Indonesia. This research uses normative research methods. The subject matter will be studied juridically normative and juridically philosophical with a systemic and comparative juridical approach. The nature of this research is descriptive, namely describing the overall object that is explored and collected systematically. The approaches used in this research are statute approach and conceptual approach. In this research, library materials in the form of secondary data are used as the main source. Secondary data includes primary legal materials, secondary legal materials and tertiary legal materials. These various data can be obtained through literature studies or online data searches. Data collection provides verification, correction, supplementation, and itemization of each other. Will be analyzed qualitatively after being collected. The results of this study, to unify inheritance law in Indonesia can be done by adjusting the elements of the applicable legal order within the framework of the legal system. In each legal system consists of 3 (three) sub-systems, namely legal substance, legal structure, and legal culture. Furthermore, to create opportunities for the unification of inheritance law in Indonesia, the steps that can be taken are studies and research related to the inheritance law system that applies in Indonesia; dialogue and discussion between stakeholders; submitting proposals and discussions at the legislative level to make rules for the unification of inheritance law in Indonesia; conducting socialization and education to the public about the importance of unification of inheritance law; and after the unification of inheritance law is passed, implementation and evaluation of its implementation are carried out.