bluuebunny/crossref_metadata_2025 huggingface dataset:
SARS-CoV-2 Infection in One Cat and Three Dogs Living in COVID-19-Positive Households in Madrid, Spain
Authors: Miró Guadalupe , Regidor-Cerrillo Javier , Checa Rocio , Diezma-Díaz Carlos , Montoya Ana , García-Cantalejo Jesús , Botías Pedro , Arroyo Javier , Ortega-Mora Luis-Miguel
Published: November 2021

In this study, we describe SARS-CoV-2 infection dynamics in one cat and three dogs from households with confirmed human cases of COVID-19 living in the Madrid Community (Spain) at the time of expansion (December 2020 through June 2021) of the alpha variant (lineage B.1.1.7). A thorough physical exam and nasopharyngeal, oropharyngeal, and rectal swabs were collected for real-time reverse-transcription PCR (RT-qPCR) SARS-CoV-2 testing on day 0 and in successive samplings on days 7, 14, 21, and 47 during monitoring. Blood was also drawn to determine complete blood counts, biochemical profiles, and serology of the IgG response against SARS-CoV-2. On day 0, the cat case 1 presented with dyspnea and fever associated with a mild bronchoalveolar pattern. The dog cases 2, 3, and 4 were healthy, but case 2 presented with coughing, dyspnea, and weakness, and case 4 exhibited coughing and bilateral nasal discharge 3 and 6 days before the clinical exam. Case 3 (from the same household as case 2) remained asymptomatic. SARS-CoV-2 detection by RT-qPCR showed that the cat case 1 and the dog case 2 exhibited the lowest cycle threshold (Ct) (Ct < 30) when they presented clinical signs. Viral detection failed in successive samplings. Serological analyses revealed a positive IgG response in cat case 1 and dog cases 3 and 4 shortly after or simultaneously to virus shedding. Dog case 2 was seronegative, but seroconverted 21 days after SARS-CoV-2 detection. SARS-CoV-2 genome sequencing was attempted, and genomes were classified as belonging to the B.1.1.7 lineage.
Perforated Steel Stud to Improve the Acoustic Insulation of Drywall Partitions
Authors: Arjunan Arun , Baroutaji Ahmad , Robinson John
Published: November 2021

Steel studs are an inevitable part of drywall construction as they are lightweight and offer the required structural stability. However, the studs act as sound bridges between the plasterboards, reducing the overall sound insulation of the wall. Overcoming this often calls for wider cavity walls and complex stud decoupling fixtures that increase the installation cost while reducing the floor area. As an alternative approach, this research reveals the potential of perforated studs to improve the acoustic insulation of drywall partitions. The acoustic and structural performance is characterized using a validated finite element model that acted as a prediction tool in reducing the number of physical tests required. The results established that an acoustic numerical model featuring fluid-structure-interaction can predict the weighted sound reduction index of a stud wall assembly at an accuracy of ±1 dB. The model was used to analyze six perforated stud designs and found them to outperform the sound insulation of non-perforated drywall partitions by reducing the sound bridging. Overall, the best performing perforated stud design was found to offer improvements in acoustic insulation of up to 4 dB, while being structurally compliant.
An Official Outbreak Investigation of Acute Haemorrhagic Diarrhoea in Dogs in Norway Points to Providencia alcalifaciens as a Likely Cause
Authors: Jørgensen Hannah Joan , Valheim Mette , Sekse Camilla , Bergsjø Bjarne Asbjørn , Wisløff Helene , Nørstebø Simen Foyn , Skancke Ellen , Lagesen Karin , Haaland Anita Haug , Rodriguez-Campos Sabrina , Sjurseth Siri Kulberg , Hofshagen Merete , Jarp Jorun , Tronerud Ole-Herman , Johannessen Gro Skøien , Heggelund Monica , Rygg Sasja , Christensen Ellen , Boye Mette , Gjerset Britt , Sandvik Morten , Soltvedt Eiril Moen , Wolff Cecilia
Published: November 2021

An outbreak investigation was initiated in September 2019, following a notification to the Norwegian Food Safety Authority (NFSA) of an unusually high number of dogs with acute haemorrhagic diarrhoea (AHD) in Oslo. Diagnostic testing by reporting veterinarians had not detected a cause. The official investigation sought to identify a possible common cause, the extent of the outbreak and prevent spread. Epidemiological data were collected through a survey to veterinarians and interviews with dog owners. Diagnostic investigations included necropsies and microbiological, parasitological and toxicological analysis of faecal samples and food. In total, 511 dogs with acute haemorrhagic diarrhoea were registered between 1 August and 1 October. Results indicated a common point source for affected dogs, but were inconclusive with regard to common exposures. A notable finding was that 134 of 325 faecal samples (41%) cultured positive for Providencia alcalifaciens. Whole genome sequencing (WGS) of 75 P. alcalifaciens isolates from 73 dogs revealed that strains from 51 dogs belonged to the same WGS clone. Findings point to P. alcalifaciens as implicated in the outbreak, but investigations are needed to reveal the pathogenic potential of P. alcalifaciens in dogs and its epidemiology.
Applying FABRIC as a Tool to Understanding Architectural and Landscape Icons in a Time of Travel Restrictions
Authors: McIntosh Jacqueline , Marques Bruno
Published: November 2021

Iconic architecture and landscape architecture are most often understood through photographic media that mediates between the idea and the reality for those learning to design. The drastic lockdown responses to COVID-19 and the limitations on local and international travel highlighted the importance of the visual and the potential of the virtual. However, visual media can also be understood as systems that go far beyond a strict representation of an object. In this climate where publicity, politics, and perception play ever more crucial roles, representations of iconic architecture and landscapes increasingly blur the boundaries between the imaginary and the tangible. This paper examines the experience of iconic architecture and landscape in four iconic European cities (Paris, Barcelona, Seville, and Lisbon) as seen through the eyes of fifty postgraduate architecture, interior architecture, and landscape architecture students from New Zealand. It compares their understanding of a building or landscape from its photographic image before engaging with the physical reality. Students were asked to first identify iconic architecture and landscape, then closely analyze and document the essential qualities which established its pre-eminence. A subsequent visit to each of the places provided the opportunity for comparison and the testing of the realities and fictions of the icons themselves. Our research finds that today’s architecture students are savvy and sophisticated consumers of technology. It also presents FABRIC (finding, assimilating, being, reflecting, introspecting, and concluding), a conceptual framework that offers additional scaffolding for educating design students through experiential learning in a time of travel restrictions.
Chemical Characterization, Source, and SOA Production of Intermediate Volatile Organic Compounds during Haze Episodes in North China
Authors: Feng Xinxin , Zhao Jinhu , Feng Yanli , Cai Junjie , Yan Caiqing , Chen Yingjun
Published: November 2021

The growth of secondary organic aerosols (SOA) is a vital cause of the outbreaks of winter haze in North China. Intermediate volatile organic compounds (IVOCs) are important precursors of SOA. Therefore, the chemical characteristics, source, and SOA production of IVOCs during haze episodes have attracted much attention. Hourly time resolution IVOC samples during two haze episodes collected in Hebei Province in North China were analyzed in this study. Results showed that: (1) the concentration of IVOCs measured was within the range of 11.3~85.1 μg·cm−3 during haze episodes, with normal alkanes (n-alkanes), polycyclic aromatic hydrocarbons (PAHs), branched alkanes (b-alkanes), and the residue unresolved complex mixture (R-UCM) accounting for 8.6 ± 2.3%, 6.8 ± 2.2%, 24.1 ± 3.8%, and 60.5 ± 6.5% of IVOCs, respectively. NC12-nC15 in n-alkanes, naphthalene and its alkyl substitutes in PAHs, b-alkanes in B12–B16 bins, and R-UCM in B12–B16 bins are the main components, accounting for 87.0 ± 0.2%, 87.6 ± 2.9%, 85.9 ± 5.4%, 74.0 ± 8.3%, respectively. (2) Based on the component characteristics of IVOCs and the ratios of n-alkanes/b-alkanes in emission sources and the hourly variation of IVOCs during haze episodes, coal combustion (CC), biomass burning (BB), gasoline vehicles (GV), and diesel vehicles (DV)were identified as important emission sources of IVOCs in Hebei Province. (3) During haze episodes, temporal variation of the estimated SOA production based on different methods (such as IVOCs concentration, OC/ECmin tracer, and the PMF model) were similar; however, the absolute values were different. This difference may be due to the transformation of IVOCs to SOA affected by various factors such as SOA production from different IVOC components, meteorological conditions, atmospheric oxidation, etc.
Thermal Response of Spring–Summer-Grown Black Gram (Vigna mungo L. Hepper) in Indian Subtropics
Authors: Banerjee Purabi , Mukherjee Bishal , Venugopalan Visha Kumari , Nath Rajib , Chandran Malamal Alickal Sarath , Dessoky Eldessoky S. , Ismail Ismail A. , El-Hallous Ehab I. , Hossain Akbar
Published: November 2021

The thermal environment of a crop is one of the prime factors enhancing growth and production by regulating its physiological processes at different phenophases. To study the impact of thermal regime on spring–summer-grown black gram (variety Pant Urd 31), an experiment was conducted with different sowing dates (from the first to the third week of March), soil application of cobalt (Co) and foliar sprays of potassium (K) and boron (B) in various combinations in the split–split plot design during 2020 and 2021. The first-week-of-March-sown crop recorded more accumulated growing degree-days (GDD), photothermal units (PTU) and heliothermal units (HTU) with a longer duration than the later sown crop. Higher daily mean temperature during the reproductive stage of the later sown crop compelled it to complete the phenophases earlier than the normally sown crop, leading to yield reduction. Soil application of Co at 4 kg ha−1 and foliar sprays of K at 1.25% and B at 0.2% mitigated the adversities of excess heat irrespective of sowing dates. Variations in GDD and HTU, respectively, explained variations of about 75.8% and 87.3% in the final dry matter accumulation and of 72.9% and 84.8% in seed yield through polynomial regressions in the respective years. The maximum mean thermal use efficiency (TUE) for biomass production (0.24 g m−2/°C/day−1) and seed yield (0.11 g m−2/°C/day−1) were observed with Co soil application and combined foliar sprays of K and B due to higher dry matter production or seed yield with lower heat units accumulation in the first sown crop.
TGFβ1 Secreted by Cancer-Associated Fibroblasts as an Inductor of Resistance to Photodynamic Therapy in Squamous Cell Carcinoma Cells
Authors: Gallego-Rentero María , Gutiérrez-Pérez María , Fernández-Guarino Montserrat , Mascaraque Marta , Portillo-Esnaola Mikel , Gilaberte Yolanda , Carrasco Elisa , Juarranz Ángeles
Published: November 2021

As an important component of tumor microenvironment, cancer-associated fibroblasts (CAFs) have lately gained prominence owing to their crucial role in the resistance to therapies. Photodynamic therapy (PDT) stands out as a successful therapeutic strategy to treat cutaneous squamous cell carcinoma. In this study, we demonstrate that the transforming growth factor β1 (TGFβ1) cytokine secreted by CAFs isolated from patients with SCC can drive resistance to PDT in epithelial SCC cells. To this end, CAFs obtained from patients with in situ cSCC were firstly characterized based on the expression levels of paramount markers as well as the levels of TGFβ1 secreted to the extracellular environment. On a step forward, two established human cSCC cell lines (A431 and SCC13) were pre-treated with conditioned medium obtained from the selected CAF cultures. The CAF-derived conditioned medium effectively induced resistance to PDT in A431 cells through a reduction in the cell proliferation rate. This resistance effect was recapitulated by treating with recombinant TGFβ1 and abolished by using the SB525334 TGFβ1 receptor inhibitor, providing robust evidence of the role of TGFβ1 secreted by CAFs in the development of resistance to PDT in this cell line. Conversely, higher levels of recombinant TGFβ1 were needed to reduce cell proliferation in SCC13 cells, and no induction of resistance to PDT was observed in this cell line in response to CAF-derived conditioned medium. Interestingly, we probed that the comparatively higher intrinsic resistance to PDT of SCC13 cells was mediated by the elevated levels of TGFβ1 secreted by this cell line. Our results point at this feature as a promising biomarker to predict both the suitability of PDT and the chances to optimize the treatment by targeting CAF-derived TGFβ1 in the road to a more personalized treatment of particular cSCC tumors.
IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model
Authors: Zhang Cuiping , Delawary Mina , Huang Peng , Korchak Jennifer A. , Suda Koji , Zubair Abba C.
Published: November 2021

Mesenchymal stem cells (MSCs) are used in various studies to induce immunomodulatory effects in clinical conditions associated with immune dysregulation such as graft versus host disease (GvHD). However, most of these clinical trials failed to go beyond early phase 2 studies because of limited efficacy. Various methods have been assessed to increase the potency of MSCs. IL-10 is an anti-inflammatory cytokine that is known to modulate immune responses in GvHD. In this study, we evaluated the feasibility of transfecting IL-10 mRNA to enhance MSC therapeutic potential. IL-10 mRNA engineered MSCs (eMSCs-IL10) maintained high levels of IL-10 expression even after freezing and thawing. IL-10 mRNA transfection did not appear to alter MSC intrinsic characteristics. eMSCs-IL10 significantly suppressed T cell proliferation relative to naïve MSCs in vitro. In a mouse model for GvHD, eMSCs-IL10 induced a decrease in plasma level of potent pro-inflammatory cytokines and inhibited CD4+ and CD8+ T cell proliferation in the spleen. In summary, our studies demonstrate the feasibility of potentiating MSCs to enhance their immunomodulatory effects by IL-10 mRNA transfection. The use of non-viral transfection may generate a safe and potent MSC product for treatment of clinical conditions associated with immune dysregulation such as GvHD.
High Glucose-Induced Apoptosis Is Linked to Mitochondrial Connexin 43 Level in RRECs: Implications for Diabetic Retinopathy
Authors: Sankaramoorthy Aravind , Roy Sayon
Published: November 2021

Diabetic retinopathy (DR) is one of the most common causes of vision loss and blindness among the working-age population. High glucose (HG)-induced decrease in mitochondrial connexin 43 (mtCx43) level is known to promote mitochondrial fragmentation, cytochrome c release, and apoptosis in retinal endothelial cells associated with DR. In this study, we investigated whether counteracting HG-induced decrease in mtCx43 level would preserve mitochondrial integrity and prevent apoptosis. Rat retinal endothelial cells (RRECs) were grown in normal (N; 5 mM glucose) or HG (30 mM glucose) medium for 7 days. In parallel, cells grown in HG were transfected with Cx43 plasmid, or empty vector (EV), as control. Western blot (WB) analysis showed a significant decrease in mtCx43 level concomitant with increased cleaved caspase-3, Bax, cleaved PARP, and mitochondrial fragmentation in cells grown in HG condition compared to those grown in N medium. When cells grown in HG were transfected with Cx43 plasmid, mtCx43 level was significantly increased and resulted in reduced cleaved caspase-3, Bax, cleaved PARP and preservation of mitochondrial morphology with a significant decrease in the number of TUNEL-positive cells compared to those grown in HG alone. Findings from the study indicate a novel role for mtCx43 in regulating apoptosis and that maintenance of mtCx43 level could be useful in preventing HG-induced apoptosis by reducing mitochondrial fragmentation associated with retinal vascular cell loss in DR.
Association of Barley Root Elongation with ABA-Dependent Transport of Cytokinins from Roots and Shoots under Supra-Optimal Concentrations of Nitrates and Phosphates
Authors: Vysotskaya Lidiya , Timergalina Leylya , Akhiyarova Guzel , Korobova Alla , Fedyaev Vadim , Ivanov Igor , Kudoyarova Guzel , Veselov Dmitry
Published: November 2021

Changes in root elongation are important for the acquisition of mineral nutrients by plants. Plant hormones, cytokinins, and abscisic acid (ABA) and their interaction are important for the control of root elongation under changes in the availability of ions. However, their role in growth responses to supra-optimal concentrations of nitrates and phosphates has not been sufficiently studied and was addressed in the present research. Effects of supra-optimal concentrations of these ions on root elongation and distribution of cytokinins between roots and shoots were studied in ABA-deficient barley mutant Az34 and its parental variety, Steptoe. Cytokinin concentration in the cells of the growing root tips was analyzed with the help of an immunohistochemical technique. Increased concentrations of nitrates and phosphates led to the accumulation of ABA and cytokinins in the root tips, accompanied by a decline in shoot cytokinin content and inhibition of root elongation in Steptoe. Neither of the effects were detected in Az34, suggesting the importance of the ability of plants to accumulate ABA for the control of these responses. Since cytokinins are known to inhibit root elongation, the effect of supra-optimal concentration of nitrates and phosphates on root growth is likely to be due to the accumulation of cytokinins brought about by ABA-induced inhibition of cytokinin transport from roots to shoots.
Numerical Analysis of an Earthen Masonry Structure Subjected to Blast Loading
Authors: Tse Demiana , Pereira João M. , Lourenço Paulo B.
Published: November 2021

Historic monuments and construction capture the knowledge of civilizations of the past and are a source of pride for people of the present. Over the centuries, these buildings have been at risk from natural and man-made causes. The Alhambra, a UNESCO World Heritage Site in Granada, Spain, is one of such places. This paper aims to evaluate the structural performance of the Torre de la Vela, a tower in the Alhambra, under blast loads. The loads were based on historical records of barrels of gunpowder and were modeled as simplified pressure profiles using existing empirical equations. The effect of impulsive loading on the material properties was accounted for using dynamic increase factors, determined experimentally by previous authors. The model was created using finite element methods (FEM) and the problem was solved using explicit dynamic analysis available in Abaqus/Explicit. Using the failure volume damage index, a blast load applied outside and inside of the building would create a low damage level, which should be treated with caution given the occurrence of localized damage. The removal of elements exceeding a given damage threshold led to more visible damage patterns than the Concrete Tension Damage option in Abaqus.
Apparent Power Laws Can Occur without Criticality
Authors: Schulman Lawrence S.
Published: November 2021

Power laws often lead to the conclusion that self-organized criticality is at work. This is not the case, and power laws can also occur away from criticality or can occur for other reasons.
Free Convective Heat Transfer in a Closed Gap between Concentric Semi-Hemispheres
Authors: Baïri Abderrahmane , Alilat Nacim , Martín-Garín Alexander , Adeyeye Kemi , Millán-García José-Antonio , Roseiro Luis
Published: November 2021

Free convective heat transfer in the closed gap between concentric semi-hemispheres is quantified by means of a numerical approach based on the volume control method using the SIMPLE algorithm. The average Nusselt number is determined for several configurations obtained by varying the cavity’s aspect ratio between 0.15 and 1.5, while the Rayleigh number varies within the 5.33 × 103–4.50 × 108 range. The results show that the correlations available in the literature dealing with concentric whole spheres cannot be used for the configuration treated here. The new correlation between the Nusselt and Rayleigh numbers proposed in this work can be applied in various engineering sectors, such as in the electronic packaging considered in this present work, buildings, and architecture.
Economic Development of the European Union in the Relation of Sustainable Development—Taxonomic Analysis
Authors: Jędrzejczak-Gas Janina , Barska Anetta , Wyrwa Joanna
Published: November 2021

The purpose of this paper is a multidimensional assessment of the diversification of economic development in EU countries in the context of the progress in the implementation of the concept of sustainable development in 2014 and 2019. The issues discussed in this article are topical and important, given that the spatial disparity of economic development in the EU has never been so pronounced as it is today. While there is a wealth of studies on economic development in the literature, research on the comprehensive approach to this problem in the relation of sustainable development appears to be rather scarce. The article emphasizes the role of energy in economic growth. Authors used taxonomic measures. They were constructed on the basis of selected methods of multidimensional comparative analysis. By using the Hellwig method and the TOPSIS method, taxonomic measures were constructed, and linear ordering of the EU countries was carried out. In addition, using the so-called threshold method, the clustering of EU countries was carried out. The analysis involved 27 EU countries. The conducted research revealed significant disproportions between the respective EU countries in terms of the level of economic development in the relation of implementing the concept of sustainable development. It seems justified to take action aimed at eliminating the differences between the countries in the analyzed aspect. It is necessary both to intensify efforts at the level of individual Member States and the EU, oriented towards pro-development activities.
Solar-Powered Cellular Base Stations in Kuwait: A Case Study
Authors: Baidas Mohammed W. , Hasaneya Rola W. , Kamel Rashad M. , Alanzi Sultan Sh.
Published: November 2021

With the rapidly evolving mobile technologies, the number of cellular base stations (BSs) has significantly increased to meet the explosive demand for mobile services and applications. In turn, this has significantly increased the capital and operational expenses, due to the increased electricity prices and energy consumption. To generate electricity, power plants mainly rely on fossil fuels, which are non-renewable energy resources. As a result, CO2 emissions also increase, which adversely affect health and environment. For wireless access technologies and cellular networks, BSs are the largest power consumer, and the network energy consumption is mainly dominated by the network infrastructure, which makes the telecommunications sector liable for energy consumption as well as CO2 emissions around the globe. Alternatively, solar energy is considered as an eco-friendly and economically attractive solution, due to its cost-effectiveness and sustainability. In this paper, the potentials of photovoltaic (PV) solar power to energize cellular BSs in Kuwait are studied, with the focus on the design, implementation, and analysis of off-grid solar PV systems. Specifically, system components, such as the number of PV panels, batteries, and converters needed for the design are determined and evaluated via HOMER software, with the focus on minimizing the net present cost (NPC). A comparison between various PV, diesel generator (DG), and battery bank (BB) system configurations is also performed. Moreover, a comparison of system deployment area will be presented for different PV panels that have different output power and panel sizes, in addition to utilizing a solar tracking system. It is revealed that utilizing a hybrid system configuration (i.e., PV-DG-BB) decreases fuel consumption per year by almost 95% in comparison to the conventional DG-only based electric systems. Not only that, but utilizing a pure off-grid solar PV system (i.e., PV-BB) can significantly reduce the total NPC while completely eliminating CO2 emissions; however, at the expense of more land.
Performance Evaluation of Harmonic Reduced Non-Overlap Winding Wound Rotor Synchronous Machine
Authors: Garner Karen S. , Kamper Maarten J. , Loubser Andrew T.
Published: November 2021

The analysis and performance evaluation of a harmonic reduction strategy of a non-overlap winding wound rotor synchronous machine is conducted in this paper. The harmonic reduction strategy utilizes phase-shifts between coil currents to reduce sub- and higher-order harmonics. The design is performed on a 3 MW wound rotor synchronous machine with a 16/18 pole/slot combination. The application results in a lowered torque ripple and an increased efficiency of the designed machine. The manufacturing and testing of a 3 kW prototype to ascertain the effectiveness of the design is also presented. The practical measurements correlate successfully with the theoretical results.
The Effect of Temperature-Pressure Conditions on the RDF Gasification in the Atmosphere of Steam and Carbon Dioxide
Authors: Śpiewak Katarzyna , Czerski Grzegorz , Bijak Karol
Published: November 2021

This research aimed to assess the process conditions, temperature and pressure, on the gasification of alternative refuse-derived fuel (RDF) in the atmosphere of steam and carbon dioxide on a laboratory scale using a fixed bed reactor. For this reason, the selected RDF were analysed, including proximate and ultimate analysis, mercury content and ash composition. After that, isothermal gasification measurements using the thermovolumetric method were performed under various temperatures (700, 750, 800, 900 °C) and pressures (0.5, 1, 1.5 MPa), using steam and carbon dioxide as gasifying agents. The obtained results showed that in the entire analysed range, the increase in temperature positively affect both the steam and CO2 gasification of RDF. The formation rates of main components (H2 and/or CO) of the resulting gas, as well as yields of gas components and maximum carbon conversion degrees increase. However, this positive effect was the greater, the lower the process pressure was. In turn, the effect of pressure was more complex. In the case of RDF steam gasification, an increase in pressure had a negative effect on the process, while when using carbon dioxide as a gasifying agent, an improvement of most analysed parameters was observed; however, only at low temperatures, 700–750 °C.
Advances in Dual-Three-Phase Permanent Magnet Synchronous Machines and Control Techniques
Authors: Zhu Ziqiang , Wang Shensheng , Shao Bo , Yan Luocheng , Xu Peilin , Ren Yuan
Published: November 2021

Multiphase electrical machines are advantageous for many industrial applications that require a high power rating, smooth torque, power/torque sharing capability, and fault-tolerant capability, compared with conventional single three-phase electrical machines. Consequently, a significant number of studies of multiphase machines has been published in recent years. This paper presents an overview of the recent advances in multiphase permanent magnet synchronous machines (PMSMs) and drive control techniques, with a focus on dual-three-phase PMSMs. It includes an extensive overview of the machine topologies, as well as their modelling methods, pulse-width-modulation techniques, field-oriented control, direct torque control, model predictive control, sensorless control, and fault-tolerant control, together with the newest control strategies for suppressing current harmonics and torque ripples, as well as carrier phase shift techniques, all with worked examples.
Voltage Rise Regulation with a Grid Connected Solar Photovoltaic System
Authors: Stephen Akinyemi Ayodeji , Musasa Kabeya , Davidson Innocent Ewean
Published: November 2021

Renewable Distributed Generation (RDG), when connected to a Distribution Network (DN), suffers from power quality issues because of the distorted currents drawn from the loads connected to the network over generation of active power injection at the Point of Common Coupling (PCC). This research paper presents the voltage rise regulation strategy at the PCC to enhance power quality and continuous operation of RDG, such as Photovoltaic Arrays (PVAs) connected to a DN. If the PCC voltage is not regulated, the penetration levels of the renewable energy integration to a DN will be limited or may be ultimately disconnected in the case of a voltage rise issue. The network is maintained in both unity power factor and voltage regulation mode, depending on the condition of the voltage fluctuation occurrences at the PCC. The research investigation shows that variation in the consumer’s loads (reduction) causes an increase in the power generated from the PVA, resulting in an increase in the grid current amplitude, reduction in the voltage of the feeder impedance and an increase in the phase voltage amplitude at the PCC. When the system is undergoing unity power factor mode, PCC voltage amplitude tends to rises with the loads. Its phase voltage amplitude rises above an acceptable range with no-loads which are not in agreement, as specified in the IEEE-1547 and Southern Africa grid code prerequisite. Incremental Conduction with Integral Regulator bases (IC + PI) are employed to access and regulate PVA generation, while the unwanted grid current distortions are attenuated from the network using an in-loop second order integral filtering circuit algorithm. Hence, the voltage rise at the PCC is mitigated through the generation of positive reactive power to the grid from the Distribution Static Compensator (DSTATCOM), thereby regulating the phase voltage. The simulation study is carried out in a MATLAB/Simulink environment for PVA performance.
Evaluation of Energy Price Liberalization in Electricity Industry: A Data-Driven Study on Energy Economics
Authors: Tabatabaei Tayebeh Sadat , Asef Pedram
Published: November 2021

This study aims to evaluate the effects of price liberalization on energy consumption intensity, because price liberalization leads to improved productivity, energy consumption management, and consumption reform. Although the energy consumption of large-scale factories and industries has increased dramatically, and the energies losses have an increment in the power transmission lines, this policy can result in decreasing the energy consumption intensity due to the changes in consumption patterns. If there is a correlation between two variables, the price can be a valid variable to control cost and increase consumption efficiency. The augmented Dickey–Fuller (ADF) and the Chi-squared tests are also employed to investigate the maneuverability of these variables in the first-order contrast. In this case study, the energy consumption intensity response to price changes using the data gathered between 1988–2020, has gained a confidence interval of these reactions at 95%. The proposed vector autoregressive (VAR) model has forecasted the action and reaction of the end-user, to investigate the future shocks between 2020–2050, considering a new price shock, in the Iranian energy market for the first time. The research findings have shown that energy price liberalization leads to the energy intensity improvement, however, the end-user (shocking) reactions should be investigated to implement a more sustainable policy that eases the new energy price rises.
Power Sharing and Control Strategy for Provisionally Coupled Microgrid Clusters through an Isolated Power Exchange Network
Authors: Ferdous S.M. , Shahnia Farhad , Shafiullah GM
Published: November 2021

The two common mechanisms of load-shedding and renewable curtailment can prevent provisional overloading and excessive generation and the subsequent unacceptable voltage and frequency deviation in standalone microgrids (MGs), which makes MGs less resilient and reliable. However, instead of enabling load-shedding or renewable curtailment, such overloading or over-generation problems can be alleviated more efficiently and cost-effectively by provisionally interconnecting the neighboring MGs to exchange power amongst themselves. In such a scheme, the interconnected MGs can supply their local demand, as well as a portion of the demand of the adjacent MGs. In order to implement this strategy, a three-phase ac link can be used as the power exchange network, while each MG is coupled to the link through a back-to-back power electronics converter, in order to maintain the autonomy of each MG if they are eachoperated under different standards. This paper proposes a suitable decentralized power management strategy without a communication link between the MGs to achieve power-sharing amongst them and alleviate unacceptable voltage and frequency deviation along with the required control technique for the power electronic converters, which can be implemented at the primary level based on the measurement of the local parameters only. To this end, one of the converters should always regulate the dc link voltage while the other converter should operate in droop control mode when the MG is healthy and in constant PQ mode when overloaded or over-generating. Suitable status detection and mode transition algorithms and controllers were also developed and are proposed in this paper. The performance of the proposed power exchange and control mechanisms were evaluated and verified via PSIM®-based numerical simulation studies. The stability and sensitivity of the proposed power exchange topology are also analyzed against several critical design and operational parameters.
Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia
Authors: Soukup Sebastian Tobias , Stoll Dominic Alexander , Danylec Nicolas , Schoepf Alena , Kulling Sabine Emma , Huch Melanie
Published: November 2021

The intake of isoflavones is presumed to be associated with health benefits in humans, but also potential adverse effects of isoflavones are controversially discussed. Isoflavones can be metabolized by gut bacteria leading to modulation of the bioactivity, such as estrogenic effects. Especially bacterial strains of the Eggerthellaceae, a well-known bacterial family of the human gut microbiota, are able to convert the isoflavone daidzein into equol. In addition, metabolization of genistein is also described for strains of the Eggerthellaceae. The aim of this study was to identify and investigate gut bacterial strains of the family Eggerthellaceae as well as the narrowly related family Coriobacteriaceae which are able to metabolize daidzein and genistein. This study provides a comprehensive, polyphasic approach comprising in silico analysis of the equol gene cluster, detection of genes associated with the daidzein, and genistein metabolism via PCR and fermentation of these isoflavones. The in silico search for protein sequences that are associated with daidzein metabolism identified sequences with high similarity values in already well-known equol-producing strains. Furthermore, protein sequences that are presumed to be associated with daidzein and genistein metabolism were detected in the two type strains ‘Hugonella massiliensis’ and Senegalimassilia faecalis which were not yet described to metabolize these isoflavones. An alignment of these protein sequences showed that the equol gene cluster is highly conserved. In addition, PCR amplification supported the presence of genes associated with daidzein and genistein metabolism. Furthermore, the metabolism of daidzein and genistein was investigated in fermentations of pure bacterial cultures under strictly anaerobic conditions and proofed the metabolism of daidzein and genistein by the strains ‘Hugonella massiliensis’ DSM 101782T and Senegalimassilia faecalis KGMB04484T.
Phenotypic Variability of MEGF10 Variants Causing Congenital Myopathy: Report of Two Unrelated Patients from a Highly Consanguineous Population
Authors: AlMuhaizea Mohammad , Dabbagh Omar , AlQudairy Hanan , AlHargan Aljouhra , Alotaibi Wafa , Sami Ruba , AlOtaibi Rahaf , Ali Mariam Mahmoud , AlHindi Hindi , Colak Dilek , Kaya Namik
Published: November 2021

Congenital myopathies are rare neuromuscular hereditary disorders that manifest at birth or during infancy and usually appear with muscle weakness and hypotonia. One of such disorders, early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD, OMIM: 614399, MIM: 612453), is a rare autosomal recessive disorder caused by biallelic mutations (at homozygous or compound heterozygous status) in MEGF10 (multiple epidermal growth factor-like domains protein family). Here, we report two unrelated patients, who were born to consanguineous parents, having two novel MEGF10 deleterious variants. Interestingly, the presence of MEGF10 associated EMARDD has not been reported in Saudi Arabia, a highly consanguineous population. Moreover, both variants lead to a different phenotypic onset of mild and severe types. Our work expands phenotypic features of the disease and provides an opportunity for genetic counseling to the inflicted families.
Family-to-Work Interface and Workplace Injuries: The Mediating Roles of Burnout, Work Engagement, and Safety Violations
Authors: Siu Oi Ling , Ng Ting Kin
Published: November 2021

Past research has primarily investigated the role of the negative side (family-to-work conflict; FWC) of the family-to-work interface in workplace safety outcomes and neglected the positive side (family-to-work enrichment; FWE). Moreover, the mechanism underlying the relation between the family-to-work interface and workplace safety has not been well studied. From the perspectives of the job demands-resources model as well as conservation of resources theory, this study endeavors to extend the current literature on workplace safety by evaluating the mediating roles of burnout, work engagement, and safety violations in the associations of FWC and FWE with workplace injuries. Two-wave longitudinal survey data were obtained from 233 Chinese employees in two high-risk industries (nursing and railways). The hypothesized longitudinal mediation model was analyzed with the structural equation modeling technique. It was revealed that the association of FWE with workplace injuries was mediated by work engagement and then safety violations. Burnout was found to mediate the association of FWC with workplace injuries. Safety violations were also found to mediate the association of FWC with workplace injuries. The present findings offer insights into the underlying mechanisms by which the family-to-work interface influences workplace injuries.
Control and Prevention of SARS-CoV-2 Outbreaks among Healthcare Workers from 129 Healthcare Facilities in Mexico
Authors: Pineda-Santoyo César , Campos-Romero Abraham , Luna-Ruiz Esparza Marco A. , López-Luna Liliana E. , Sánchez-Zarate Martha E. , Zepeda-González Abraham , Fernández-Rojas Miguel A. , Alcántar-Fernández Jonathan
Published: November 2021

Few reports have shared the workflows to reduce SARS-CoV-2 infections among risk groups, including healthcare workers (HCWs). This study describes an occupational health program implemented to reduce the incidence of COVID-19 and establishes a back-to-work algorithm in HCWs of 129 Salud Digna outpatient care clinics in Mexico. This program was composed of training plans, screening SARS-CoV-2 infections, the containment of infections, follow-up COVID-19 cases, and continuing supervision in addition to the steady supply and training for the correct use of PPE. From 16 April 2020 to 15 April 2021, 7376 individuals were enrolled, of which 423 were excluded because they did not meet the inclusion criteria or refused the follow-up. In the cohort studied, we found a COVID-19 incidence of 35.4% (2610 individuals), lower hospitalization (0.11%), ICU (0.04%) and lethality rate (0.04%). Additionally, 85.9% of COVID-19 cases tested negative for SARS-CoV-2 after 14 days of the first positive test with an average isolation time of 26–33 days. Finally, 99% of people received personal protective equipment and adequate training to use it. Our results show that the program implemented reduced the hospitalization ICU admission and lethality in HCWs; we consider this workflow to help other workplaces offer safe conditions for HCWs and patients.
A Systematic Review of a Polyvagal Perspective on Embodied Contemplative Practices as Promoters of Cardiorespiratory Coupling and Traumatic Stress Recovery for PTSD and OCD: Research Methodologies and State of the Art
Authors: Poli Andrea , Gemignani Angelo , Soldani Federico , Miccoli Mario
Published: November 2021

Baseline respiratory sinus arrhythmia (RSA) has been proposed as a transdiagnostic biomarker of stress vulnerability across psychopathologies, and a reliable association between PTSD, OCD and lower resting RSA was found. Contemplative practices have been linked to the activation of the vagus as well as to an increased RSA that, according to the polyvagal theory, reflects the activation of the ventral vagal complex (VVC) and may promote PTSD and OCD recovery. PubMed and Scopus databases were selected to conduct a search following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) 2020 guidelines, and A MeaSurement Tool to Assess systematic Reviews-2 (AMSTAR-2) was used to appraise the methodological quality for this systematic review. Six articles met the inclusion criteria (one cross-sectional study, one study with pre-post measurements, two cohort studies and two RCT studies). Mindfulness-related interventions promoted parasympathetic activity, an increased vagal tone and improvements in PTSD and OCD symptoms. According to the polyvagal theory, mindfulness-related and compassion-related meditations would be conceptualized as neural exercises expanding the capacity of the ventral vagal complex to regulate the present state and to promote resilience. Clinical and methodological issues are discussed.
Elite Badminton Is Getting Older: Ages of the Top 100 Ranked Badminton Players from 1994 to 2020
Authors: Abián Pablo , Simón-Chico Luis , Bravo-Sánchez Alfredo , Abián-Vicén Javier
Published: November 2021

The purpose of this study was to determine the evolution of the age of badminton players in the top 100 of the World Ranking for men and women from 1994 to 2020. Data were collected from badminton players participating in the top 100 World Rankings (4800 entries: 1233 players; 595 men and 638 women) from 1994 to 2020. The mean age of the top 100 and the average highest ranking of the players were analysed for both genders. The mean age of the male players in the World Ranking increased from 23.7 ± 3.2 years in 1994 to 26.3 ± 4.4 years in 2020 (p < 0.001) and in female players, from 22.8 ± 3.8 years in 1994 to 24.7 ± 3.3 years in 2020 (p < 0.001). In addition, women recorded a younger age at entry into the top 100 and when reaching their best ranking. Additionally, there has been a clear increase in Asian players in the top 100 of the World Ranking in recent years, reaching over 60%. These data could be used to develop and organise training plans in this sport, optimising and maximising players’ performance.
Sleep Disorders in Early Childhood and the Development of Mental Health Problems in Adolescents: A Systematic Review of Longitudinal and Prospective Studies
Authors: Lam Lawrence T , Lam Mary K
Published: November 2021

The association between sleep problems, particularly sleep disorders, and mental health has long been studied and recognized. However, the causal relationship between sleep disorders, particularly during early childhood, on mental health problems in adolescence are yet to be established. From a preventive perspective, it is important to understand the causality of mental health problems in adolescents so that intervention measures can be derived and implemented as early as possible for maximum effectiveness. To provide more precise information on the effect of early childhood sleep disorders on mental health problems during adolescence, a systematic review was conducted on longitudinal and prospective studies reported in the literature. Following the PRISMA guidelines with an extensive search of the literature 26 studies were identified. Seven of these identified studies satisfied all selection criteria with sufficient data on the effect of early childhood sleep disorders and mental health problems in adolescence. Information was extracted and analyzed systematically from each study and tabulated. The overall results obtained from these studies indicate a significant and possible causal relationship between early childhood sleep disorders and the development of mental health problems, such as anxiety, depression, and ADHD in adolescence. These results are discussed with regards to the theoretical and practical implications as well as preventive strategies.
Differences in Work Disability Duration for Immigrants and Canadian-Born Workers in British Columbia, Canada
Authors: Senthanar Sonja , Koehoorn Mieke , Tamburic Lillian , Premji Stephanie , Bültmann Ute , McLeod Christopher B.
Published: November 2021

This study aimed to investigate differences in work disability duration among immigrants (categorized as economic, family member or refugee/other classification upon arrival to Canada) compared to Canadian-born workers with a work-related injury in British Columbia. Immigrants and Canadian-born workers were identified from linked immigration records with workers’ compensation claims for work-related back strain, connective tissue, concussion and fracture injuries requiring at least one paid day of work disability benefits between 2009 to 2015. Quantile regression investigated the relationship between immigration classification and predicted work disability days (defined from injury date to end of compensation claim, up to 365 days) and modeled at the 25th, 50th and 75th percentile of the distribution of the disability days. With a few exceptions, immigrants experienced greater predicted disability days compared to Canadian-born workers within the same injury cohort. The largest differences were observed for family and refugee/other immigrant classification workers, and, in particular, for women within these classifications, compared to Canadian-born workers. For example, at the 50th percentile of the distribution of disability days, we observed a difference of 34.1 days longer for refugee/other women in the concussion cohort and a difference of 27.5 days longer for family classification women in the fracture cohort. Economic immigrants had comparable disability days with Canadian-born workers, especially at the 25th and 50th percentiles of the distribution. Immigrant workers’ longer disability durations may be a result of more severe injuries or challenges navigating the workers’ compensation system with delays in seeking disability benefits and rehabilitation services. Differences by immigrant classification speak to vulnerabilities or inequities upon arrival in Canada that persist after entry to the workforce and warrant further investigation for early mitigation strategies.