bluuebunny/crossref_metadata_2025 huggingface dataset:
VDR mRNA overexpression is associated with worse prognostic factors in papillary thyroid carcinoma
Authors: Choi June Young , Yi Jin Wook , Lee Jun Hyup , Song Ra-Yeong , Yu Hyeongwon , Kwon Hyungju , Chai Young Jun , Kim Su-jin , Lee Kyu Eun
Published: February 2017

The purpose of this study was to assess the relationship between vitamin D receptor gene (VDR) expression and prognostic factors in papillary thyroid cancer (PTC). mRNA sequencing and somatic mutation data from The Cancer Genome Atlas (TCGA) were analyzed. VDR mRNA expression was compared to clinicopathologic variables by linear regression. Tree-based classification was applied to find cutoff and patients were split into low and high VDR group. Logistic regression, Kaplan–Meier analysis, differentially expressed gene (DEG) test and pathway analysis were performed to assess the differences between two VDR groups. VDR mRNA expression was elevated in PTC than that in normal thyroid tissue. VDR expressions were high in classic and tall-cell variant PTC and lateral neck node metastasis was present. High VDR group was also associated with classic and tall cell subtype, AJCC stage IV and lower recurrence-free survival. DEG test reveals that 545 genes were upregulated in high VDR group. Thyroid cancer-related pathways were enriched in high VDR group in pathway analyses. VDR mRNA overexpression was correlated with worse prognostic factors such as subtypes of papillary thyroid carcinoma that are known to be worse prognosis, lateral neck node metastasis, advanced stage and recurrence-free survival.
Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality
Authors: Bancos Irina , Hazeldine Jon , Chortis Vasileios , Hampson Peter , Taylor Angela E , Lord Janet M , Arlt Wiebke
Published: February 2017

Objective

Mortality in patients with primary adrenal insufficiency (PAI) is significantly increased, with respiratory infections as a major cause of death. Moreover, patients with PAI report an increased rate of non-fatal infections. Neutrophils and natural killer (NK) cells are innate immune cells that provide frontline protection against invading pathogens. Thus, we compared the function and phenotype of NK cells and neutrophils isolated from PAI patients and healthy controls to ascertain whether altered innate immune responses could be a contributory factor for the increased susceptibility of PAI patients to infection.

Design and methods

We undertook a cross-sectional study of 42 patients with PAI due to autoimmune adrenalitis (n = 37) or bilateral adrenalectomy (n = 5) and 58 sex- and age-matched controls. A comprehensive screen of innate immune function, consisting of measurements of neutrophil phagocytosis, reactive oxygen species production, NK cell cytotoxicity (NKCC) and NK cell surface receptor expression, was performed on all subjects.

Results

Neutrophil function did not differ between PAI and controls. However, NKCC was significantly reduced in PAI (12.0 ± 1.5% vs 21.1 ± 2.6%, P < 0.0001). Phenotypically, the percentage of NK cells expressing the activating receptors NKG2D and NKp46 was significantly lower in PAI, as was the surface density of NKG2D (all P < 0.0001). Intracellular granzyme B expression was significantly increased in NK cells from PAI patients (P < 0.01).

Conclusions

Adrenal insufficiency is associated with significantly decreased NKCC, thereby potentially compromising early recognition and elimination of virally infected cells. This potential impairment in anti-viral immune defense may contribute to the increased rate of respiratory infections and ultimately mortality in PAI.
Índice temático de los números 51 a 60 (Subject Index of Issues 51-60)
Authors: Dirección Letras
Published: February 2017

Índice temático de los números 51 a 60 Subject Index of Issues 51-60
Índice general de los números 51 a 60 (General Index of Issues 51-60)
Authors: Dirección Letras
Published: February 2017

Índice general de los números 51 a 60General Index of Issues 51-60
Apuntes para una tipología de la semiosfera literaria en Roberto Bolaño (Notes for a Typology of the Literary Semiosphere in Roberto Bolaño)
Authors: Soto Bogantes Carlos
Published: February 2017

Desde la semiótica de la cultura (Lotman) se propone un acercamiento textual a la narrativa de Roberto Bolaño. Se acude a los conceptos de semiosfera y el texto en el texto. El análisis se centra en algunos elementos significativos, la memoria, entre ellos. Se procura sistematizar el modelo de semiosfera literaria a partir de la obra del escritor chileno.From the perspective of the semiotics of culture (Lotman), a textual approach is proposed for the narrative of Roberto Bolaño. Reference is made to semiosphere and the text within the text. The analysis focuses on significant elements, such as memory. The aim is to systematize the model of literary semiosphere in the works of the Chilean writer.
Pengaruh Ion Na+, Ion Hg2+ dan Ion Cr3+ Terhadap Kinerja Sensor Potensiometri Ion Timbal (II) Tipe Kawat Terlapis Berbasis Pirofilit
Authors: Fardiyah Qanitah , Berlianti Barlah , Rosemiyani Ika
Published: February 2017

Generally ionophores  (active materials) in a potentiometric is derived from organic compounds. In this research used ionophores derived from ainorganic compounds that pyrophyllite. Potentiometric sensors lead (II) ions based on pyrophyllite as ionofor has been developed. The electrode had  polyvinilchloride (PVC) as polymer matrix and dioctylpthalate (DOP) as plasticizer. It showed a good Nernstian slope of 29.33 mV/decade, a lead linear range concentration between 10-1- 10-5 M, and detection limit of 8.054 x10-6 M  (equal with 1.669 ppm of lead). By using the electrode, the objectives of this research were to investigate the effect of interfering ions  Na+, ion Hg2+ and ion Cr3+ to the performance of the potentiometric sensors lead(II) ion based pyrophyllite coated wire type. The selective coefficients (kij) were determined using the mix solution methode  at  10-3 M of interfering ion. The result showed that the potentiometric sensors lead(II) ions based  on pyrophyllite coated wire type could be used optimally at  pH 5. The potentiometric sensors lead(II) ion based pyrophyllite coated wire type showed a good selectivity for interfering ions (Na+, Hg2+, dan Cr3+) and showed no interference to the performance of the potentiometric sensors lead (II) ion based pyrophyllite coated wire type with selectivity order of Pb2+> Hg2+> Cr3+> Na+. DOI :http://dx.doi.org/10.15408/jkv.v0i0.3144
Penentuan Hidrokuinon dalam Sampel Krim Pemutih Wajah secara Voltammetri Menggunakan Screen Printed Carbon Electrode (SPCE)
Authors: Mulyasuryani Ani , Savitri Alfita
Published: February 2017

Hydroquinone in whitening face cream has been banned since 2008, but is still found facial bleaching creams containing hydroquinone. Therefore, in this study have been developed voltammetric method for the determination hydroquinone in face whitening cream. This study has been carried out optimization of pH and measurement conditions. Optimizationof pH has been done in cyclic voltammetry, while the optimization of measurement carried out by differential pulse voltammetry. In this study, using a screen printed carbon electrode with a three electrode system. The results showed that the increase in pH causes a decrease in the anodic peak potential (Epa) of hydroquinone. The optimum conditions resulted at pH 2 in which the anodic current (Ipa) is the highest. The optimum condition resulted at high pulse 200 mV and scan rate at 15 mV/sec. The linear regression concentration is 1-100 μM, limit of detection is 0.015 μM and sensitivity is 0.0652 μM/µA. The results showed that the concentration of hydroquinone in the face whitening cream samples ranged from 0 to 0.02%DOI :http://dx.doi.org/10.15408/jkv.v0i0.3145.
Karakterisasi Karbon Aktif Asal Tumbuhan dan Tulang Hewan Menggunakan FTIR dan Analisis Kemometrika
Authors: Siregar Yusraini Dian Inayati , Heryanto Rudy , Lela Nur , Lestari Tri Heny
Published: February 2017

Activated carbon is widely used as an adsorbent in gas purification, refining pulp, and also for the purification of food products, among others, oil purification, refining cane sugar, beet sugar, corn sugar, eliminate the taste and odor of drinking water. Carbon active can be derived from plant and animal bone. This study aims to analyze the differences in spectral profile of activated carbon from plants and animal bones by using FTIR. The data combined with the results of FTIR analysis chemometrics to classify and categorize the data, so it is clear where the activated carbon from plants and animal bones. FTIR analysis methods combined with chemometrics analysis through modeling PCA (Principal Component Analysis) and PLS-DA (Partial Least Squares-Discriminant Analysis) is able to distinguish between activated carbon derived from plants (coconut shell) and animal bones (beef and pork). PCA with total diversity of 89% were able to classify the samples of activated carbon plant and animal bones. PLSDA models successfully predicted the test sample is based on a sample group of activated carbon raw material. Manufacture of activated carbon predictive models with PLS calibration generates R2, R2 predictions, RMSEC, and RMSEP respectively by 0.9787389, 0.9662152, 0.0687364 and 0.0928362. The results showed that FTIR spectra and can be used to distinguish chemometrics activated carbon derived from plant and animal bonesDOI :http://dx.doi.org/10.15408/jkv.v0i0.3146.
Penggunaan Kitosan sebagai Koagulan Alami dalam Perbaikan Kualitas Air Danau
Authors: Hendrawati Hendrawati , Sumarni Susi , Nurhasni .
Published: February 2017

Treatment of groundwater and surface water is still dirty often done using synthetic coagulant poly aluminum Cloride (PAC). In fact, its use may pose a risk to health and more expensive. This study was conducted to see the effect of chitosan from shrimp shell waste as a natural coagulant coagulant synthetic substitute. Chitosan at a concentration of 20 ppm lower the lake water turbidity of 94.43%, lowering the pH, decreases the amount of bacteria ± 99.18%. Lower levels of dissolved metals in the water of the lake, such as manganese, magnesium and iron. Chitosan does not change tempeatur lake water and water treatment results. Chitosan not lower BOD value and not lower levels of calcium. DOI :http://dx.doi.org/10.15408/jkv.v0i0.3148
Fat Reduction in Improving the Quality of Chicken Feet Gelatine for Functional Food Application
Authors: Melanie Hakiki , Susilowati Agustin , Iskandar Jeti M , Laelatunur Meilita
Published: February 2017

Fat reduction has been performed on crude gelatin extracted from chicken feet (shank) through curing process using sodium hydroxide and acetic acid in various proportions. This study was conducted to evaluate the best fat reduction condition by the addition of acetic acid at concentrations of 0, 2.5 and 5% (v/v) with decantation time 0, 6 and 12 hours on crude gelatine from curing process at a ratio of 1% acetic acid; 1% acetic acid with 1% NaOH; 1% acetic acid and 3% NaOH and without curing (initial gelatine). The analysis was carried out to determine the composition of gelatin and their byproducts to total solids, total fat and fat binding capacity. The results showed that the variation in the ratio of the addition of acetic acid and decantation time affect the composition of fat and fat-binding ability. Based on fat binding capacity (FBC), treatment of chicken feet gelatin with curing of 1% acetic acid and 3% NaOH and continued by the addition of 5% (v/v) acetic acid with a 12-hour decantation time resulted in gelatin with the best FBC of 7.4 g/g, fat content 1.0248% and total solids 2.7575%.DOI : http://dx.doi.org/10.15408/jkv.v0i0.3149
Aplikasi Metode SDS-PAGE (Sodium Dodecyl Sulphate Poly Acrylamide Gel Electrophoresis) untuk Mengidentifikasi Sumber Asal Gelatin pada Kapsul Keras
Authors: Hermanto Sandra , Saputra Fahrur Rahman , . Zilhadia
Published: February 2017

Gelatin as the main ingredient of capsules is still a problem for a moslem. Most of gelatin production remains largely derived from non-halal materials. One of gelatin source is came from collagen of the skin and bones of bovine or pork. The main of study is determine the source of gelatin used in hard capsules by using SDS-PAGE (Sodium Dodecyl Sulphate Gel electrophoresis Poly Acrylamide) method. In the early stages, optimization of standards bovine and pork gelatin were hydrolyzed by pepsin at pH 4.5 and 60°C for 1 hour, 2 hours, and 3 hours. Gelatin hydrolyzateswere analyzed by SDS-PAGE to determine the optimal hydrolysis time. Identification of gelatin hydrolyzate fragments were carried by molecular weight. Hydrolysis time optimization throught applied to identify the source of hard gelatin capsules in the samples obtained from market and compared with the simulation of hard gelatin capsules. The results showed there were of specific bands of bovine gelatin with a molecular weight of 11,4 kDa; 34 kDa; 47kDa and specific bands of pork gelatin with a molecular weight of 24.7 kDa; 28 kDa; and 60 kDa. Similar results were obtained on a sample of hard capsules with bands of protein fragments that were identical to bovine gelatinstandard. Based on the results,each of the samples were tested contain of bovine gelatin respectively. DOI :http://dx.doi.org/10.15408/jkv.v0i0.3150
Kuersetin dan Kuersetin-3-O-Glukosida dari Kulit Batang Sonneratia Alba (Lythraceae)
Authors: Horizon . , Pujiastuti Betry , Kurnia Dikdik , Sumiarsa Dadan , Supratman Unang , Shiono Yoshihito
Published: February 2017

Two flavonoid compounds, quercetin (1) and quercetin-3-O-glucoside (2) have been isolated from the bark of Sonneratia alba (Lythraceae). Chemical structure of both compounds were determined on the basis of spectroscopic data and comparison with those spectra data previously reported. Compound 1 and 2 exhibited antibacterial activity against Gram-positive bacteria, Staphylococcus aureus and Streptococcus mutans with MIC values of 51.2; 48.8; 72.5; dan 100.7 µg/mL respectively.DOI :http://dx.doi.org/10.15408/jkv.v0i0.3151
Biosorpsi Ni2+ oleh Nannochloropsis Salina pada Medium Terpapar Ca2+
Authors: Hala Yusafir , Zakir Muhammad , Suryati Emma , Azis Karuniawati
Published: February 2017

Research on biosorption of Ni2+ by N. salina in Ca2+ exposed medium has been done.  This study aimed to determine the growth and efficiency of N. salina towards Ni2+ in Conwy Medium with addition of Ca2+.  Exposure of mixed ions of Ni2+ 5 ppm and Ca2+ with variation of concentrations 10, 30, 50 ppm was conducted at the beginning of the growth of N. salina.  The growth of N. salina was observed every day by counting the number of N. salina population using a microscope and haemocytometer.  The concentration of metal ions after the exposure was determined by atomic absorption spectrophotometer.  The growth of N. salina in medium with exposed metal ions is lower than the control.  The maximum sorption efficiency of Ni2+ as a single ion is 55.2%. After exposure of mixed ions of Ni2+ and Ca2+ with variation of concentrations 10, 30, 50 ppm, the sorption efficiency of Ni2+ in sequents are 17.6%; 17.8%; and 19.6%; while the maximum sorption efficiency of N. salina towards Ca2+ are 5.1%; 7.1%; and 4.0% respectively.DOI :http://dx.doi.org/10.15408/jkv.v0i0.3153
Aktivitas Antioksidan dan Kandungan Komponen Bioaktif Sari Buah Namnam
Authors: Adawiah Adawiah , Sukandar Dede , Muawanah Anna
Published: February 2017

Antioxidant is a compoud  inhibit that have an important role in protecting health due to it can absorb free radical molecules and inhibit oxidative reaction which cause anykinds of diseases. This study aims to determine the chemical compositition and antioxidant  activity of namnam juice, characteristic of namnam. In this experimental, proximat analysis, TPC, TFC, Vitamin C, antioxidant activity were evaluated. Namnam juice contains 996.03 mg/L of phenolics, 421.09 mg/Lof flavonoids, 121.44 mg/100mL of vitamin C and high antioxidant activity with IC50 5µL/mL.DOI :http://dx.doi.org/10.15408/jkv.v0i0.3155.
Preparation and Characterization Of Co3O4 Nano Powder
Authors: Yanti Pepi Helza , Mukhtar Akmal , Astarina .
Published: February 2017

Synthesis of Co3O4 has been done using Co(NH3)4.6H2O and KOH as precursors with molar ratio 1:1 M with precipitation method. Several of calcination temperature were done to learn type of mineral phase and crystalinity of Co3O4 synthesized. The XRD analysis revealed that calcination temperature influence crystalinity and mineral phase of Co3O4 prepared and calcination temperature at 700 oC has highest intensity and crystalinity that others. Analysis of particle size was examined using Schererr equation, and the results showed that particle size decrease with calcination temperature. The particle size at  700 oC was = 32.387 nm. Analysis morphology of Co3O4 was examined using SEM technique, and the result revelaed Co3O4 have nearly spherical.DOI :http://dx.doi.org/10.15408/jkv.v0i0.3176.
Peningkatan Mutu Briket dari Sampah Organik dengan Penambahan Minyak Jelantah dan Plastik High Density Polyethylene (HDPE)
Authors: Septhiani Silvia , Septiani Eka
Published: February 2017

The objective of this research was to looking for the alternative fuel to overcome the limitations of natural resources by using organic garbage and to investigate the improvement quality of biobriket after HDPE and cooking oil addition. Making biobriket with carbonitation organic garbage was a method that is used. The result of the research suggests that the quality of biobriket increased after HDPE and cooking oil addition.  The analysis of water biobriket showed that HDPE was decreased from 13.99% to 13.88% and biobriket of cooking oil is 9.39%. More over the decreasing also happened to the content of the ash, from 25% to 23% biobriket HDPE and 20% to biobriket of cooking oil. Calorific biobriket 4703.27 cal/g, the increasing of HDPE biobriket was 5009.16 cal/g and biobriket of cooking oil 6245.66 cal/g. DOI :http://dx.doi.org/10.15408/jkv.v0i0.3567.
Prevalencia de defectos de desarrollo del esmalte en dentición temporal, en una población bogotana
Authors: Osorio Tovar Johana Patricia , Naranjo Sierra María Claudia , Rodriguez Godoy Mauricio
Published: February 2017

Objetivo Determinar en un área con fluorización sistémica, la prevalencia de defectos de desarrollo del esmalte en dentición temporal de niños/niñas entre 4 y 6 años de un colegio público de Bogotá, Colombia.Método En 153 escolares se realizó muestreo aleatorio simple obteniendo 62 niños sistémicamente sanos en quienes se valoraron clínica y detalladamente los dientes.  La examinadora fue calibrada con una experta en el índice modificado de Defectos de Desarrollo del Esmalte de la Federación Dental Internacional obteniendo Kappa interexaminador de 0,9 e intraexaminador de 0,8. Se contó con consentimiento informado y aprobación del estudio por parte del Comité de Ética de la Facultad de Odontología de la Universidad Nacional.Resultados La prevalencia de DDE fue de 74,2 % (IC 95 % 62,1-83,4) distribuidos en: opacidades demarcadas 86,9 % (IC 95 % 74,3-93,3), opacidades difusas 76,1 % (IC 95 % 62,4-85,7) e hipoplasias 2,2 % (IC 95 % 0,4-11,1). La combinación de defectos más frecuente en un mismo individuo fue opacidades demarcadas y difusas. El maxilar más afectado fue el superior 54,6 % y los dientes más comprometidos fueron los segundos molares 56 %. El promedio de dientes afectados con DDE por individuo fue de 4,7 ± DE 2,6.Conclusiones La alta prevalencia de defectos de desarrollo del esmalte encontrada, así la severidad haya sido baja, debe alertar a órganos decisores en salud para ejercer controles orientados a prevenirlos. Se deben realizar más estudios con metodologías estandarizadas para llegar a conocer la prevalencia global de los defectos.
Frecuencia de dermatomicosis y factores asociados en población vulnerable de la ciudad de Manizales. Colombia. 2011
Authors: Estrada Salazar Gloria Ines , Chacón-Cardona José A.
Published: February 2017

Resumen:Objetivo: Determinar la frecuencia de las dermatomicosis en personas de diferentes instituciones de atención social en la ciudad de Manizales durante el año 2011. Método: Mediante la toma de muestras de los sitios que presentaban algún tipo de lesión sospechosa de ser una micosis cutánea, se hizo un análisis directo con KOH y cultivo en medios de Saboureaud y Mycosel. Se aplicó un instrumento de recolección de información para establecer  factores asociados con la presencia de estos microorganismos.Resultados: Los hongos levaduriformes encontrados con mayor frecuencia fueron: Candida albicans, Trichosporon sp, y los mohos saprofitos Penicillium sp, fusarium sp; seguido de hongos dermatofitos como: Trichophyton mentagrophites, Trichophyton rubrum, Epidermophyton floccosum y Microsporum gypseum. Las lesiones secas y descamativas se encontraron con mayor frecuencia. El compartir baños y vivir en hacinamiento y el uso de elementos comunes fueron los factores asociados más importantes en este estudio.Conclusiones. Las dermatomicosis son frecuentes en poblaciones vulnerables y se asocian a diferentes factores muy similares a los encontrados en otros estudios de igual naturaleza.    Palabras clave: dermatomicosis, onicomicosis, jóvenes, ancianos, factores asociados. Summary:Objective: To determine the frequency of ringworm in people of different social care institutions in the city of Manizales in 2011.Method: Using the sampling sites that had some kind of suspicious lesion from a cutaneous mycosis, direct analysis with KOH and culture media was Saboureaud and Mycosel. An instrument of data collection was used to establish factors associated with the presence of these microorganisms.Results: The yeast found most frequently were: Candida albicans, Trichosporon sp and Penicillium molds saprophytes sp, Fusarium sp, followed by dermatophyte fungi such as Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum. Dry scaly lesions were found more frequently. The shared bathrooms and living in overcrowded and the use of common elements were the most important in this study associated factors.Conclusions: Dermatomycoses are common in vulnerable populations and are associated with different very similar to those found in other studies of the same nature factors. Keywords: ringworm, onychomycosis, young, old, associated factors.
Calidad bacteriológica del agua para consumo en tres regiones del Perú
Authors: Tarqui Mamani Carolina Beatriz
Published: February 2017

Objetivos Determinar la calidad bacteriológica del agua para consumo en tres regiones del Perú. Materiales y Método Se realizó un estudio transversal. La recolección de datos se realizó en Cajamarca, Huancavelica y Huánuco durante el 2012-2013. El muestreo fue probabilístico, estratificado multietápico. Incluyó 706 viviendas. Se evalúo presencia de coliformes totales y E. coli mediante el kit Readycult ®. Se recolectó 100 mL de agua utilizada para preparación de alimentos. La determinación de cloro residual se realizó mediante análisis semicuantitativo (Chlorine Test®). Se estableció como concentración ideal de cloro residual ≥0,5 mg/L. El análisis de datos se realizó mediante muestras complejas con factor de ponderación. Se calcularon porcentajes y chi cuadrado. Se definió buena calidad bacteriológica: agua con cloro libre adecuado, ausencia de coliformes totales y E. coli. Se solicitó el consentimiento informado del jefe del hogar.Resultados Del total de muestras evaluadas, 78,6 % tuvieron coliformes totales en Cajamarca, 65,5 % en Huancavelica y 64,1 % en Huánuco, El 72,0 % tuvieron E. coli en Cajamarca, 37,4 % en Huancavelica y 17,5 % Huánuco. En Cajamarca, el 8,6 % de las muestras de agua fueron de buena calidad bacteriológica, mientras que en Huancavelica fue 4,3% y en Huánuco, 7,2 %.Conclusiones La mayoría de las muestras de agua tuvieron mala calidad bacteriológica evidenciándose coliformes totales. Las tres cuartas partes de los hogares de Cajamarca, la tercera parte de Huancavelica y casi la quinta parte de Huánuco tuvieron E. coli en el agua de consumo humano.
How can we promote and facilitate effective study skills in medical students?
Authors: Shaw Sebastian Charles Keith
Published: February 2017

This article was migrated. The article was marked as recommended. In my early years of medical school I always felt that I never learnt how to learn. When studying an MSc in Medical Education, it became apparent to me that this feeling may be commonplace amongst other medical students.Study skills can be defined as "the effective use of appropriate techniques for completing a learning task..." These are of vital importance in any educational setting - allowing learners to tackle and absorb information appropriately and efficiently. Although study skills are recognised as an essential ability, they may be overlooked by many medical curricula. This paper therefore aims to provide insight into the self-directed learning process and the development of appropriate study skills.The self-directed learning process is discussed - using an adapted form of the Self-directed Learning Cycle of Butler and Winne. This involves: the domains of learning; identifying learning deficits; setting learning goals; identifying efficient learning strategies; monitoring progress and strategy modification; and reaching goals. I also discuss the importance of learning style recognition, maintaining the desire to learn and possible methods for the assessment of study skills in medical students.Effective study skills are a vital tool in the medical student's arsenal against the vast quantity of information presented to them. These allow the learner to appropriately filter and assimilate information. When both understood and mastered, an individual can adapt these to the fit needs of various knowledge requirements.Through the understanding of memory and the core principles of learning, educators can hope to promote and facilitate the development of such study skills. In doing this, we can help our students to become self-sufficient, effective members of the medical community.
A Model for Sustaining Evidence-Based Practices in a Statewide System
Authors: Lang Jason M. , Randall Kellie G. , Delaney Michelle , Vanderploeg Jeffrey J.
Published: February 2017

Over the past 20 years, efforts have been made to broadly disseminate evidence-based practices (EBPs). However, the public health impact of EBPs has yet to be realized and most EBPs are not sustained. Few structured models exist for disseminating and sustaining EBPs across large systems. This article describes the EBP Dissemination and Support Center (DSC) model and how it was used to sustain trauma-focused cognitive behavioral therapy (TF-CBT) across Connecticut. More than 600 clinicians at 35 agencies have been trained and nearly all agencies have sustained TF-CBT for up to 9 years. More than 6,200 children have received TF-CBT and have shown improvements in outcomes and quality indicators. Recommendations are made for using or adapting the DSC model.
Building Field Agencies' Capacity to Prepare Staff and Social Work Students for Evidence-Based Trauma Treatments
Authors: Strand Virginia C. , Popescu Marciana , Way Ineke , Jones Annette Semanchin
Published: February 2017

Preparing MSW students to use an evidence-based approach to practice and implement empirically supported treatment protocols is imperative for social work education. Both classroom education and field experience are needed. Six schools of social work collaborated with field agencies to assist them in developing the capacity to implement evidence-based trauma treatments (EBTTs) and train social work students in these models. The study used a multisite, interrupted-time series design to assess organizational readiness to implement EBTTs at an agency. Faculty used the National Implementation Research Network implementation framework in their consultation with agencies. Findings from three agencies are used to explore the tasks in each implementation stage. Implications include the possibility of leveraging the motivation of field agencies to collaborate with schools of social work in order to implement evidence-based practice. Results also point to the relevance of using an implementation framework to guide capacity building.
Behaviour of anchored pile wall excavations in clays
Authors: Ali Jamal , Khan Abdul Q.
Published: February 2017

A database of 35 case histories of anchored pile walls, collected mainly from Chicago, Boston, Texas and Washington, DC, USA as well as Taiwan, has been evaluated to predict the performance of deep excavations in clays. Various factors (including excavation depth, undrained shear strength, wall bending stiffness, factor of safety and pile embedment) affecting the deformation characteristics of excavations supported by anchored pile walls are presented and compared with findings of previous researchers. The normalised maximum wall displacement δHmax/He falls in the range of 0·1–0·7% and the location of δHmax is at a depth of 0·4He to 1·0He. Normalised maximum ground surface settlement δVmax/He is in a range of 0·1–0·4%. The ratio of maximum surface settlement to maximum lateral displacement falls in the range of 0·7–1·4, with an average value of 1·0. Maximum wall displacements are dependent on undrained shear strength and factor of safety and decrease with an increase in these factors. Maximum wall displacements decrease by increasing wall stiffness and most of the cases are bounded by values of EI/He between 35 MNm and 120 MNm. The effect of system stiffness is more pronounced in soft clays whereas deformations in stiff clays are less dependent on system stiffness.
Uncertainty, Curreny Exess Returns, and Risk Reversals
Authors: Husted Lucas , Rogers John , Sun Bo
Published: February 2017

In this paper we provide strong evidence that heightened uncertainty in the U.S. real economy or financial markets significantly raises excess returns to the currency carry trade. We posit that this works through the influence of uncertainty on global investors' risk preferences. Macro and financial uncertainty also lower foreign exchange risk reversals, an effect that is particularly strong for high interest rate portfolios. Our results are consistent with the idea that an increase in uncertainty regarding the U.S. economy or financial markets increases investors' risk aversion, which in turn drives up the expected returns and the cost of protection against crash risk in the FX market.
EDUCAÇÃO ÉTNICO-RACIAL NA ESCOLA: A LEI 10639/2003 E OS DESAFIOS DA INTERDISCIPLINARIDADE PARA ALÉM DAS AULAS DE HISTÓRIA
Authors: GEVEHR DANIEL LUCIANO , DE ALVES DARLÃ
Published: February 2017

Analisa-se o ensino da cultura afro-brasileira e africana no contexto escolar, a partir de uma perspectiva interdisciplinar. Iniciamos o estudo, a partir de um levantamento que procurou reunir publicações nacionais sobre o tema da cultura afro-brasileira e africana. A partir deste levantamento, discutimos as diversas possibilidades de abordagem do tema são tornadas obrigatórias a partir da publicação da Lei 10639/2003. A Lei que determina o ensino de cultura afro-brasileira e africana na educação básica permite a proposição de ações e práticas pedagógicas, que tratam da cultura afro-brasileira e africana a partir de projetos interdisciplinares no currículo escolar. Para tanto, discutimos a aplicação de uma proposta interdisciplinar realizada em uma escola da rede municipal de Campo Bom (RS).
Imhotep renasce na sala de aula: a utilização do filme A Múmia (1932) no ensino de História do Egito
Authors: Fortes Lia Cristine , Balém Wellington Rafael
Published: February 2017

: Tanto o ensino de História quanto o cinema como recurso didático, como fonte e como História têm sido amplamente debatidos atualmente, demonstrando o interesse e a importância dessas temáticas. Neste artigo discutimos o papel de um filme específico no ensino de História do Antigo Egito no processo de formação de professores. Para isso, analisamos as experiências de exibição e análise do filme “A Múmia” (Universal, 1932) a partir das problemáticas levantadas pelos alunos da licenciatura em História da Universidade de Caxias do Sul. Partimos de algumas metodologias básicas para o uso de cinema em sala de aula e, então, entramos em aspectos mais específicos da exibição, do conteúdo e da análise de “A Múmia”. Justificamos esta escolha por este ser um filme que consolidou a “múmia” no imaginário popular como uma personagem de terror e mistério, influenciando diretamente as dezenas de filmes sobre o tema produzidos até os dias de hoje. Defendemos, assim, a necessidade de uma abordagem que permita aos alunos estabelecerem relações dialógicas entre a historicidade das temáticas das quais o filme trata e a historicidade da obra em si, superando visões generalistas e reducionistas sobre determinados aspectos da história egípcia.
Entre a norma e o fato urbano-metropolitano: possibilidades e limitações das inovações institucionais para a gestão territorial na Região Metropolitana de Campinas-SP / Between the standard and the urban and metropolitan fact: possibilities and limitations of institutional innovations for territorial management in the Metropolitan Region of Campinas-SP
Authors: Moreira Junior Orlando
Published: February 2017

Resumo

A ideia central deste trabalho é apresentar as possibilidades para a gestão e o planejamento urbano e regional advindas com as inovações institucionais trazidas pela Constituição de 1988 e pelo Estatuto da Cidade de 2001. Para exemplificar, é utilizado o caso do processo de regionalização, em especial, a criação legal de região metropolitana, tendo como referencial empírico a Região Metropolitana de Campinas-SP. A partir deste caso, é possível identificar os desafios enfrentados na transposição do plano das ideias para o plano da aplicação daquilo que consta nos documentos oficiais. Isto evidencia um descompasso entre a norma e o fato urbano e metropolitano, ampliando os desafios para o estabelecimento de uma governança metropolitana efetiva.

Abstract

The central idea of this paper is to present the possibilities for the management and urban and regional planning stemming from the institutional innovations introduced by the 1988 Constitution and the 2001 Statute of the City. As an example we use the case of the regionalization process, in particular the legal creation of the metropolitan area, with the empirical reference of the Metropolitan Region of Campinas-SP. From this case it is possible to identify the challenges faced in the implementation plan of the ideas for the transition from the of the ideas to the implementation of the plan of what appears in official documents. This reflects a mismatch between the standard and the urban and metropolitan fact, increasing the challenges for the establishment of an effective metropolitan governance.
Territorio, elites y redes socio-institucionales en la Provincia de Córdoba, Argentina, hacia el siglo XX. Modelos en disputa, industrialismo vs agronegocios / Territory, elites and socio-institucional networks in the province of Córdoba, Argentina, to the twentieth century. Models in dispute, industrialism vs agribusiness
Authors: Emiliozzi Analia Laura , Donadoni Mónica Adriana , Civitaresi Héctor Martín
Published: February 2017

Resumen

El análisis de la emergencia y consolidación de redes de distinta naturaleza y alcance asigna una importancia creciente dentro de los estudios territoriales. Diferentes autores consideran al territorio como un conjunto de relaciones políticas, económicas, sociales, culturales y ecológicas que se caracterizan como una red construida sobre una historia territorial.

En este artículo se hace hincapié en la estructura espacial y económica en la región sur de la provincia de Córdoba, Argentina, con foco en la ciudad de Río Cuarto, identificando las redes socio-institucionales construidas por las élites dominantes y sus principales vínculos a través del tiempo.

Abstract

Analysing emergence and consolidation of networks from different nature and scope assigns increasing importance within territorial studies. Different authors consider to territory as a set of political, economic, social, cultural and ecological relationships characterized as a network built on a territorial history. This article emphasises in the spatial and economic structure in the southern region of the province of Cordoba, Argentina, with focus in Rio Cuarto City, identifying the institutional networks built by dominant elites and their main links through time.

Resumo

A análise da emergência e consolidação de redes de diferente natureza e alcance atribui uma importância crescente nos estudos territoriais. Diferentes autores consideram o território como um conjunto de relações econômicas, sociais, culturais, ecológicas e políticas, caracterizados como uma história construída sobre uma rede territorial. Este artigo enfatiza a estrutura espacial e econômica na região sul da Província de Córdoba, Argentina, com o foco na cidade de Rio Cuarto, identificando as redes institucionais construídas pelas elites dominantes e suas principais ligações através do tempo.
A construção de sentidos pela Argumentação na Língua: blocos semânticos em um debate sobre o Estatuto da Família
Authors: Lopes Marildo De Oliveira , Pereira Márcia Helena De Melo , Da Silva Adilson Ventura
Published: February 2017

Este artigo objetiva discutir, por meio de uma análise linguística, a construção de sentidos possibilitada pelos encadeamentos argumentativos evocados nas falas dos deputados Ronaldo Fonseca e Jean Wyllys, em um debate acerca do Estatuto da Família - Projeto de Lei 6.583/13 - que objetiva restringir o conceito de família aos casais heterossexuais e filho (s). Essa análise se dá à luz da Teoria dos Blocos Semânticos (TBS), criada por Oswald Ducrot e Marion Carel (2005), fase mais expressiva da Teoria da Argumentação na Língua (ANL). A TBS defende que a argumentação está na própria língua e que discursos são evocados por meio de encadeamentos argumentativos – que são a combinação de dois segmentos de um enunciado, unidos pelos conectores PORTANTO (DC) e NO ENTANTO (PT), que estabelecem interdependência semântica entre eles. Um encadeamento argumentativo pertence a um bloco semântico composto de quatro aspectos argumentativos. Para atingir nosso propósito, transcrevemos o debate em questão, realizamos um estudo bibliográfico acerca do tema e prosseguimos com a análise do nosso corpus. Selecionamos dois excertos das falas de cada debatedor que melhor ilustram a evocação de encadeamentos argumentativos. Isso nos possibilitou elaborar quatro aspectos argumentativos para o bloco semântico defendido por cada deputado e mais quatro aspectos argumentativos que compõem o bloco oposto. Nossos dados comprovam que a própria língua possui orientação argumentativa e que os sentidos são construídos a partir da argumentação. Além disso, confirmamos que a argumentação é materializada na relação entre entidades linguísticas.
Norma jurídica da LEI MARIA DA PENHA EM AÇÃO: análise pragmático-cognitiva
Authors: Rauen Fábio José , Ribeiro Ana Claudia Souza
Published: February 2017

Neste artigo, guiados pela noção teórica de conciliação de metas de Rauen (2014), analisamos como a norma jurídica da Lei Maria da Penha é acionada em um caso de oferecimento de representação contra um agressor e solicitação de medidas protetivas à vítima. A análise sugere que a petição inicial se organizada em torno da norma jurídica, pois a seção de fatos qualifica o representado como transgressor da norma dispositiva, a seção de direitos destaca sanções para a transgressão, e a seção de pedidos decorre destas premissas. Os dados indicam que o texto funciona como hipótese abdutiva antefactual habilitadora, ao viabilizar que o juiz faça inferências similares e defira as medidas pela força lógica da conjunção dos fatos com o texto da Lei.
Argumentação
Authors: Souza Antonio Escandiel de
Published: February 2017

O presente texto trata-se de uma resenha da obra intitulada "Argumentação", de José Luiz Fiorin, publicada no ano de 2015 pela Editora Contexto, com ISBN: 978-85-7244-886-4.
Significação e argumentação
Authors: Carel Marion
Published: February 2017

Je me propose dans cet article de revenir sur la question très générale de la signification des mots. Quelles valeurs en effet une langue associe-t-elle aux mots et à quoi servent ces valeurs dans la détermination du sens de nos discours ? La réponse actuellement banale est que les mots décrivent le monde et que leurs significations, systématiquement exprimées, s’ajoutent, brique après brique, pour déterminer le sens de nos discours. C’est cette réponse banale que je vais discuter. M’appuyant sur les travaux d’Anscombre et Ducrot, je défendrai l’hypothèse que la signification des mots est, non pas informative, mais argumentative. Je ne veux pas dire par là que parler consiste en un effort pour persuader. Parler ne consiste pas plus à persuader qu’à décrire le monde. Ce que je défends, c’est que parler consiste à construire un texte, à entrelacer les mots, à les mettre en regard, ou encore à les présenter comme se généralisant ou s’exemplifiant, à les opposer. Parler consiste à construire un texte qui, entrant dans une conversation, à la fois fera écho au discours de l’autre et contraindra sa réponse.
INTERNET E RELIGIÃO: O CANDOMBLÉ DE YOUTUBE
Authors: Dos Santos Messias Ivan , Alberto Ferreira Danon Carlos
Published: February 2017

Objetivo: Este texto defende que a internet democratizou a dinâmica das relações humanas e, mais especificamente, da cultura religiosa. O canal Youtube é um modo de consagração e radicalização do modelo democrático virtual, na medida em que as religiões, inclusive a Umbanda e o Candomblé, participam, promovem-se e se potencializam através da exposição de vídeos. Métodos: Os vídeos de entrevistas, testemunhos, festas religiosas, músicas e ritos no site Youtube  são analisados sob enfoque filosófico e sócio-político de teóricos da comunicação como  Pierry Levy, Muniz Sodré, J. Burguess, os quais contribuem nas reflexões sobre virtualização, mídia, informação, cultura e sociedade; autores como Altair T`Ogun, José Beniste, Márcio de Jagun, V. Betancourt reforçam esta escrita através de materiais e textos sobre tradição e dinâmica religiosa. Discussão: Por isso, em um segundo momento das reflexões, este texto mostra o quanto a perda e a debilidade física são produtoras de cultura. Ao contrário do que se pensa, a internet conserva e fortalece as tradições e a identidade religiosa; aumenta a possibilidade de aprendizagem e acesso a saberes antes escondidos. Os relatos no Youtube sobre vivência e trajetória dos indivíduos revelam que a cultura também provém da dor e da doença - consequentemente, apresentam outra abordagem sobre tradição, ancestralidade e oralidade. Enfim, este artigo focaliza a interação entre tecnologias da informação e religião, entre condicionamento corporal e cultura.
PSICANÁLISE E UNIVERSIDADE: A EXPERIÊNCIA DO ESTÁGIO EM PSICOLOGIA CLÍNICA COM ORIENTAÇÃO PSICANALÍTICA
Authors: Da Silva José Antonio Pereira , Coelho Maria Thereza Ávila Dantas , Pontes Suely Aires
Published: February 2017

Este estudo tem como objetivos: analisar o conteúdo da produção de literatura sobre a prática de estágio supervisionado em psicologia clínica, com orientação psicanalítica, e refletir sobre a formação do psicólogo, suas dificuldades e desafios. Trata-se de uma revisão de literatura sistemática, através da qual se realizou o levantamento de artigos nacionais e estrangeiros para mapear a produção do conhecimento acerca da experiência de estágio supervisionado em psicologia clínica com orientação psicanalítica. A pesquisa foi feita no SCIELO.ORG, BVS-PSI e Portal de Periódicos-CAPES/MEC, através das palavras-chave: estágio, psicologia clínica e psicanálise. Os artigos mostram que há uma tensão própria à relação da psicanálise com a universidade. Para que haja trabalho clínico, essa tensão não poderá ser tomada pelo estagiário no registro da impotência, mas do impossível que precisamente convoca ao trabalho, destacando-se que é preciso se perguntar qual é a clínica possível, a partir da psicanálise, no contexto universitário. Os pesquisadores demonstram que o estágio supervisionado em clínica-escola pode se constituir como um espaço formador e transformador para o estudante de psicologia e seu posicionamento ético ante a diversidade. Verifica-se que essa experiência não é sem consequência para pacientes, estagiários e supervisores. Recorrendo a noções cruciais da psicanálise, os autores mostram como, na formação do psicólogo clínico de orientação psicanalítica, trata-se, sobretudo, de suportar e assentir com as posições éticas às quais o estágio convoca.
RELAÇÃO ENTRE A AUTOPERCEPÇÃO DO ESTADO DE SAÚDE E A AUTOMEDICAÇÃO ENTRE ESTUDANTES UNIVERSITÁRIOS
Authors: Dantas Coelho Maria Thereza Ávila , Dos Santos Vanessa Prado , Do Carmo Maria Beatriz Barreto , De Souza Adailton Conceição , Xavier França Carolina Pereira
Published: February 2017

Objetivo: Relacionar criticamente a autopercepção acerca do estado de saúde e doença e a prática de automedicação entre estudantes de um curso de saúde. Metodologia: Utilizou-se um questionário semi-estruturado sobre as concepções de saúde e doença e práticas de autocuidado entre estudantes de um curso de saúde na cidade de Salvador, Bahia. Resultados: Responderam ao questionário503 estudantes, dentre os quais 82% se perceberam como saudáveis, 82% procuravam assistência médica quando doentes e apenas18% referiram a prática da automedicação. Entre os que se percebiam como doentes, houve significativamente uma maior frequência de referências à automedicação como prática adotada, quando comparados aos que se referiram como saudáveis(30% versus 16%) (p=0,04). Conclusão: O estudo sugere uma relação entre a autopercepção do estado de saúde e a automedicação como prática adotada, entre os pesquisados. O baixo percentual de automedicação encontrado nesta amostra de ingressantes, quando comparado a estudos com indivíduos em processo mais avançado de formação profissional, pode servir como um alerta aos cursos de saúde, apontando para a própria caminhada dentro do curso como um elemento que influencia a prática da automedicação.
DE ‘MESTRE EXPLICADOR’ A ‘MESTRE IGNORANTE’: CONSIDERAÇÕES SOBRE O PAPEL DO TUTOR NO MÉTODO DA ABP (APRENDIZAGEM BASEADA EM PROBLEMAS) NUM CURSO DE PSICOLOGIA EM SALVADOR, BAHIA - RELATO DE EXPERIÊNCIA
Authors: Barbosa Guedes Lidiane de Fátima , Do Carmo Maria Beatriz Barreto
Published: February 2017

Trata-se de um relato de experiência decorrente do encontro de duas professoras-tutoras iniciantes no trabalho com o método da ABP, no curso de Psicologia da EBMSP. A Aprendizagem Baseada em Problemas (ABP) é uma metodologia ativa de ensino-aprendizagem, na qual os papéis de professores e alunos assumem formas e lugares distintos daqueles representados pelo referencial da pedagogia tradicional, sendo o professor deslocado para o lugar de tutor. No presente relato de experiência, a obra filosófico-literária “O mestre ignorante: cinco lições sobre a emancipação intelectual”, do filósofo francês Jacques Rancière, foi tomada como analisador do papel do tutor no método da ABP. A referida obra aborda uma situação experimental de aprendizagem na qual os alunos aprendem na ausência da explicação do professor-mestre. Discute-se neste trabalho as perspectivas de embrutecimento e emancipação, decorrentes do processo de ensino-aprendizagem, a partir dos referenciais do método da ABP. Concluímos que a presença viva e forte do corpo do mestre/tutor impulsionará a emancipação intelectual dos estudantes, apontando para o Princípio da Igualdade como estratégia central da aprendizagem sem mestre explicador, mas não sem mestre.