bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital-Twin-Based Real-Time Optimization for a Fractional Order Controller for Industrial Robots
Authors: Liu Xuan , Gan He , Luo Ying , Chen Yangquan , Gao Liang
Published: February 2023

Digital twins are applied in smart manufacturing towards a smarter cyber-physical manufacturing system for effective analysis, fault diagnosis, and system optimization of a physical system. In this paper, a framework applying a digital twin to industrial robots is proposed and realizes the real-time monitoring and performance optimization of industrial robots. This framework includes multi-domain modeling, behavioral matching, control optimization, and parameter updating. The properties of the industrial robot are first modeled in a digital environment to realize the strong interactive and all-around 3D visual monitoring. Then, behavioral matching is performed to map the virtual system to the physical system in real time. Furthermore, the control performance of the system is improved by using a fractional order controller based on the improved particle swarm optimization algorithm. This framework is applied to the experimental verification of real-time control optimization on an industrial robot. The time-domain performance is improved in the simulation and experimental results, where the overshoot is promoted at least 42%, the peak time is promoted at least 32%, and the settling time is promoted at least 33%. The simulation and experimental results demonstrate the effectiveness of the proposed framework for a digital twin combined with fractional order control (FOC).
Telomere Length, a New Biomarker of Male (in)Fertility? A Systematic Review of the Literature
Authors: Fattet Anne-Julie , Chaillot Maxime , Koscinski Isabelle
Published: February 2023

Male factors are suspected in around half cases of infertility, of which up to 40% are diagnosed as idiopathic. In the context of a continuously increased resort to ART and increased decline of semen parameters, it is of greatest interest to evaluate an additional potential biomarker of sperm quality. According to PRISMA guidelines, this systematic review of the literature selected studies evaluating telomere length in sperm and/or in leukocytes as a potential male fertility biomarker. Twenty-two publications (3168 participants) were included in this review of experimental evidence. For each study, authors determined if there was a correlation between telomere length and semen parameters or fertility outcomes. Of the 13 studies concerning sperm telomere length (STL) and semen parameters, ten found an association between short STL and altered parameters. Concerning the impact of STL on ART results, the data are conflicting. However, eight of the 13 included studies about fertility found significantly longer sperm telomeres in fertile men than in infertile men. In leukocytes, the seven studies reported conflicting findings. Shorter sperm telomeres appear to be associated with altered semen parameters or male infertility. Telomere length may be considered as a new molecular marker of spermatogenesis and sperm quality, and thus is related to male fertility potential. However, additional studies are needed to define the place of the STL in the assessment of individual fertility.
A Novel DLG1 Variant in a Family with Brugada Syndrome: Clinical Characteristics and In Silico Analysis
Authors: d’Apolito Maria , Santoro Francesco , Santacroce Rosa , Cordisco Giorgia , Ragnatela Ilaria , D’Arienzo Girolamo , Pellegrino Pier Luigi , Brunetti Natale Daniele , Margaglione Maurizio
Published: February 2023

Background: Brugada syndrome (BrS) is an inherited primary channelopathy syndrome associated to sudden cardiac death. Overall, variants have been identified in eighteen genes encoding for ion channel subunits and seven genes for regulatory proteins. Recently, a missense variant in DLG1 has been found within a BrS phenotype-positive patient. DLG1 encodes for synapse associated protein 97 (SAP97), a protein characterized by the presence of multiple domains for protein–protein interactions including PDZ domains. In cardiomyocytes, SAP97 interacts with Nav1.5, a PDZ binding motif of SCN5A and others potassium channel subunits. Aim of the Study: To characterize the phenotype of an Italian family with BrS syndrome carrying a DLG1 variant. Methods: Clinical and genetic investigations were performed. Genetic testing was performed with whole-exome sequencing (WES) using the Illumina platform. According to the standard protocol, a variant found by WES was confirmed in all members of the family by bi-directional capillary Sanger resequencing. The effect of the variant was investigated by using in silico prediction of pathogenicity. Results: The index case was a 74-year-old man with spontaneous type 1 BrS ECG pattern that experienced syncope and underwent ICD implantation. WES of the index case, performed assuming a dominant mode of inheritance, identified a heterozygous variant, c.1556G>A (p.R519H), in the exon 15 of the DLG1 gene. In the pedigree investigation, 6 out of 12 family members had the variant. Carriers of the gene variant all had BrS ECG type 1 drug induced and showed heterogeneous cardiac phenotypes with two patients experiencing syncope during exercise and fever, respectively. The amino acid residue #519 lies near a PDZ domain and in silico analysis suggested a causal role for the variant. Modelling of the resulting protein structure predicted that the variant disrupts an H-bond and a likelihood of being pathogenic. As a consequence, it is likely that a conformational change affects protein functionality and the modulating role on ion channels. Conclusions: A DLG1 gene variant identified was associated with BrS. The variant could modify the formation of multichannel protein complexes, affecting ion channels to specific compartments in cardiomyocytes.
Hereditary Cancer Syndrome in a Family with Double Mutation in BRIP1 and MUTYH Genes
Authors: D’Elia Giovanna , Caliendo Gemma , Passariello Luana , Albanese Luisa , Makker Jasmine , Molinari Anna Maria , Vietri Maria Teresa
Published: February 2023

Hereditary cancer syndromes predispose to several types of cancer due to inherited pathogenic variants in susceptibility genes. We describe the case of a 57-year-old woman, diagnosed with breast cancer, and her family. The proband belongs to a family with a suspected tumor syndrome, due to other cancer cases in her family from the paternal and maternal sides. After oncogenetic counseling, she was subjected to mutational analysis with an NGS panel analyzing 27 genes. The genetic analysis showed two monoallelic mutations in low penetrance genes, c.1187G>A (p.G396D) in MUTYH and c.55dup (p.Tyr19Leufs*2) in BRIP1. One of the mutations was inherited from the maternal side and the other from the paternal side, suggesting two different cancer syndrome types in the family. MUTYH mutation was related to the onset of cancers on the paternal side, as confirmed by the occurrence of the same mutation in the proband’s cousin. BRIP1 mutation was found in the proband’s mother, indicating that it was related to the cancer cases observed on the maternal side, including breast cancer and sarcoma. Advances in NGS technologies have allowed the identification of mutations in families with hereditary cancers in genes other than those related to a specific suspected syndrome. A complete oncogenetic counseling, together with molecular tests that enable a simultaneous analysis of multiple genes, is essential for the identification of a correct tumor syndrome and for clinical decision-making in a patient and his/her family. The detection of mutations in multiple susceptibility genes allows the initiation of early risk-reducing measures for identified mutation carriers among family members and to include them in a proper surveillance program for specific syndromes. Moreover, it may enable an adapted treatment for the affected patient, permitting personalized therapeutic options.
Networks as Biomarkers: Uses and Purposes
Authors: Alfano Caterina , Farina Lorenzo , Petti Manuela
Published: February 2023

Networks-based approaches are often used to analyze gene expression data or protein–protein interactions but are not usually applied to study the relationships between different biomarkers. Given the clinical need for more comprehensive and integrative biomarkers that can help to identify personalized therapies, the integration of biomarkers of different natures is an emerging trend in the literature. Network analysis can be used to analyze the relationships between different features of a disease; nodes can be disease-related phenotypes, gene expression, mutational events, protein quantification, imaging-derived features and more. Since different biomarkers can exert causal effects between them, describing such interrelationships can be used to better understand the underlying mechanisms of complex diseases. Networks as biomarkers are not yet commonly used, despite being proven to lead to interesting results. Here, we discuss in which ways they have been used to provide novel insights into disease susceptibility, disease development and severity.
Reconceptualizing Somatic Dysfunction in the Light of a Neuroaesthetic Enactive Paradigm
Authors: Consorti Giacomo , Castagna Carmine , Tramontano Marco , Longobardi Mauro , Castagna Paolo , Di Lernia Daniele , Lunghi Christian
Published: February 2023

Background: Palpatory findings are considered a central element of osteopathic practice, especially when associated with a patient’s altered regulative functions than with named somatic dysfunctions. Although osteopathic theories for somatic dysfunction could be plausible, the clinical applicability of the concept is debated, especially because it is largely related to simple cause–effect models of osteopathic care. In contrast to a linear kind of diagnosis of a “tissue as a producer of symptoms”, this perspective article aims to provide a conceptual and operational framework in which the somatic dysfunction evaluation process is seen as a neuroaesthetic (en)active encounter between osteopath and patient. Subsections relevant to the subject: To summarize all concepts of the hypothesis, the enactive neuroaesthetics principles are proposed as a critical foundation for the osteopathic assessment and treatment of the person, specifically addressing a new paradigm for somatic dysfunction. Conclusions, and future directions: The present perspective article represents a proposition to blend technical rationality informed by neurocognitive and social sciences, and professional artistry clinical experience informed by traditional tenets, to overcome the controversy around somatic dysfunction, rather than dismissing the concept.
Swimmers with Down Syndrome Are Healthier and Physically Fit than Their Untrained Peers
Authors: Querido Ana , Costa Mário J. , Araújo Dália , Sampaio António R. , Vilas-Boas João P. , Corredeira Rui , Daly Daniel J. , Fernandes Ricardo J.
Published: February 2023

While there are positive benefits from physical activity participation for individuals with Down syndrome, little is known about the effects of swimming training. The aim of this study was to compare the body composition and physical fitness profile of competitive swimmers and moderately active (untrained) individuals with Down syndrome. The Eurofit Special test was applied to a group of competitive swimmers (n = 18) and a group of untrained individuals (n = 19), all with Down syndrome. In addition, measurements were taken to determine body composition characteristics. The results showed differences between swimmers and untrained subjects in height, sum of the four skinfolds, body fat %, fat mass index and all items of the Eurofit Special test. Swimmers with Down syndrome exhibited physical fitness levels near to the Eurofit standards, although lower fitness levels were attained by these persons when compared to athletes with intellectual disability. It can be concluded that the practice of competitive swimming seems to counteract the tendency for obesity in persons with Down syndrome and also helps to increase strength, speed and balance.
Application of Color Doppler with 3- and 4-Dimensional Ultrasonography in the Prenatal Evaluation of Fetal Extracardiac and Placental Abnormalities
Authors: Leung Kwok-Yin
Published: February 2023

Using color Doppler flow imaging or high-definition flow imaging with three-dimensional volume or spatio-temporal image correlation (STIC) in the glass-body mode allows displaying both gray-scale and color information of the heart cycle-related flow events and vessel spatial relationship. Conventionally, STIC in the glass-body mode has been used to examine the fetal heart and assess heart defects. Recently, a novel application of STIC in the visualization of abdominal precordial veins and intraplacental vascularization in singleton pregnancies has been reported. The aim of this present review is to discuss the use of color Doppler with three- and four-dimensional ultrasonography in the evaluation of extracardiac, placental, umbilical cord and twin abnormalities with examples. The glass-body mode is complementary to conventional 2D ultrasonography. Further studies are required to investigate use of the glass-body mode in the assessment of intraplacental vascularization in singleton and twin pregnancies.
Psychometric Properties of the 11-Item De Jong Gierveld Loneliness Scale in a Representative Sample of Mexican Older Adults
Authors: Giraldo-Rodríguez Liliana , Álvarez-Cisneros Teresa , Agudelo-Botero Marcela
Published: February 2023

Recent studies have focused on the negative effects of loneliness on health and quality of life in older adults. The De Jong Gierveld Loneliness Scale (DJGLS) has been widely used and has proven to be a valid and reliable instrument for loneliness assessment. However, research on this topic and on the validation of measurement scales among the older population is still incipient. The objective of this study was to examine the psychometric properties of the Spanish version of the 11-item DJGLS in Mexican older adults. Data from a representative sample of cognitively intact older adults aged 60 years and over (mean, standard deviation [SD]) age = 72.0 years (SD 8.1) from two Mexican cities (n = 1913), interviewed face to face at their homes during 2018–2019, were analyzed. The psychometric properties of the DJGLS were examined, including (1) construct validity, examined by Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA), discriminate validity and convergent validity, (2) reliability, calculated using Cronbach’s alpha. The overall data quality was high, and the scaling assumptions were generally met with few exceptions. Using EFA and CFA, the findings showed that the DJGLS presents a two-factor structure (Social Loneliness and Emotional Loneliness), with 11 items that explain 67.2% of the total variance. Reliability is adequate at the full-scale level (Cronbach´s α = 0.899), also for the two subscales Social and Emotional Loneliness (Cronbach´s α = 0.892 and 0.776, respectively). These results highlight that most participants with a low score for depressive symptoms and or with a high social support score belonged to the “No loneliness” group. The results showed that the Spanish version of the 11-item DJGLS is adequate for use in Mexican older adults and should be used not only for loneliness screening but also for social and emotional loneliness assessment.
Can Acupuncture Improve the Flexibility of Hamstring Muscles? A Randomized, Blinded, and Controlled Pilot Study
Authors: Carvalho Rui Miguel , Machado Jorge , Santos Maria João , Matos Luís Carlos
Published: February 2023

(1) Background: The lack of flexibility is frequently reported as a risk factor for hamstring muscle damage. Acupuncture, a therapeutic tool of traditional Chinese medicine (TCM), may play a role in both treatment and prevention by improving muscle strength, microcirculation, and reducing muscle soreness. The primary objective of this pilot study was to examine the immediate effects of acupuncture on hamstring muscle stretching and on the pain or discomfort reported during stretching. (2) Methods: To mitigate heterogeneity effects, and due to the small sample size, the study employed a crossover design in which each participant was tested at three different moments of the experimental period with verum (true acupuncture in selected acupoints), sham (fake acupuncture in zones of the skin not corresponding to any known acupoint but near the selected acupoints), and placebo (stimulation of the selected acupoints with a stainless steel wire and cannula, without puncturing) stimulations. Flexibility and pain or discomfort were assessed using the seat and reach test (SR) and a visual analogic scale (VAS). (3) Results: Significant changes in flexibility were observed after verum acupuncture (p = 0.03), while no significant changes were seen in sham and placebo (p = 0.86 and p = 0.18, respectively). No significant differences were found in pain or discomfort during any of the stimulations (verum, p = 0.55; sham, p = 0.50; placebo, p = 0.58). (4) Conclusions: The results of this pilot study suggest that acupuncture may improve flexibility in the hamstring muscles, though it does not significantly affect pain or discomfort during stretching.
Determinants of Physical Activity among Children with Disabilities
Authors: Alghamdi Salmah , Alsaigh Rasha
Published: February 2023

Maintaining children’s physical activity levels is crucial to preventing obesity and improving their health and well-being. However, achieving the recommended daily level of 60 min of moderate-to-vigorous intensity physical activity can be difficult for children with disabilities. Moreover, children with disabilities spend less time engaging in physical activity than their typically developing peers. This study aimed to assess the personal, environmental, and social determinants of physical activity among children with disabilities. This quantitative, cross-sectional study was conducted through an online survey of a convenient sample, including 125 parents of children with disabilities aged between 5 and 18 years from different regions in the Kingdom of Saudi Arabia. Approximately 40.8% of the participants were aged between 41 and 50 years, and 57.6% (the participants and friends of their children) did not engage in regular exercise. Statistically significant differences were observed between the perception of children’s health and physical activity summary scores and the engagement of children’s friends in physical activity and physical activity summary scores. Efforts should be made to reinforce parents’ perceptions of their children’s health regarding physical activity and to support the social determinants of physical activity that ensure their children’s friends’ engagement. Specialized interventional studies are needed to support parents with children.
Be Prosocial My Friend: The Social Disconnection Model of Perfectionism in Adolescents Immersed in Competitive Sport
Authors: Rodríguez-Franco Alvaro , Carlo Gustavo , Valdivia-Moral Pedro , González-Hernández Juan
Published: February 2023

The aim of the present study is to explore the relationships between cognitive–behavioral patterns of perfectionism in the context of competitive sport and both prosociality and aggressiveness in a sample of adolescents competing in federated sports. A cross-sectional and non-randomized study was designed using a selective methodology on a sample of adolescents (N = 234) competing in federated sports. Scales to assess aggressiveness, perfectionism, prosocial behavior, and competitiveness were administrated. The results show that as age increases, prosocial behaviors increase and aggressive behaviors and competitiveness decrease, while there was no one significant perfectionist tendency. Competitiveness showed a direct relationship with aggressive (positive) and prosocial behaviors (negative). Self-oriented perfectionistic behavior showed a direct and significant relationship with prosocial behaviors, but no significant relationship with aggressive responses. As P-SP and P-OD tendencies increased, significantly smaller links were shown with prosocial behaviors, but greater links were shown with aggressive behaviors. A path (mediation) model showed a positive and predictive relationship with aggressive behaviors and a negative relationship with prosocial altruistic behaviors. The negative influence of criticism from significant figures in their environment and unrealistic expectations about their performance are relevant to difficulties in self-regulating social relationships in adolescents. Hence, it is a challenge to promote prosocial resources (as a protective value for aggressive behaviors) in the face of the early angst of young athletes, who put their maturity to the test under conditions of high pressure and demands. The present study continues to reinforce the line drawn on perfectionism and prosocial development in young people in sports contexts where young people, measured early on according to their performance, can accentuate and deepen competitive tendencies that alter their adaptive and self-regulatory capacities, as well as their psychosocial projection.
I Don’t Want to Be Thin! Fear of Weight Change Is Not Just a Fear of Obesity: Research on the Body Mass Anxiety Scale
Authors: Styk Wojciech , Wojtowicz Ewa , Zmorzynski Szymon
Published: February 2023

Anxiety is one of the psychological factors associated with body weight experienced by people attempting to live up to expectations of an ideal body shape. The stigma of excessive or too low body weight and the stigmatization of people because of it is becoming a widespread problem with negative psychological and social consequences. One effect of the strong social pressure of beauty standards dependent on low body weight is the development of eating disorders and negative societal attitudes toward overweight or obese people. Research conducted to date has mainly focused on one dimension of weight-related anxiety—the fear of getting fat. Ongoing research has also revealed the other side of weight-related anxiety—fear of weight loss. Therefore, the purpose of the present project was to develop a two-dimensional scale to diagnose the level of weight-related anxiety and to preliminarily test the psychometric properties of the emerging constructs. Results: the BMAS-20 weight-related anxiety scale in both Polish and English versions was developed and its psychometric properties were confirmed. The components of body weight-change anxiety that emerged were: anxiety about getting fat and anxiety about losing weight. It was found that both AGF and ALW may have a protective function related to awareness of the negative consequences of poor eating and the health risks associated with it. Above-normal levels of anxiety may be a predictor of psychopathology. Both AGF and ALW are associated with symptoms of depression.
Online Physical Exercise and Group Sessions to Increase and Maintain Physical Activity in Individuals with Type 2 Diabetes: A Single-Arm Feasibility Study
Authors: Mortensen Sofie Rath , Pedersen Mathilde Espe , Skou Søren T. , Ried-Larsen Mathias
Published: February 2023

Current physical activity interventions for individuals with Type 2 diabetes do not accommodate the needs of the individual in terms of content, time, and location. The aim of this study was to evaluate the feasibility and acceptability of an 8-week high intensity online physical exercise intervention combined with online group meetings and supported by an activity watch in individuals with Type 2 diabetes. This study was designed as a one-armed feasibility study and the intervention was developed using a co-creation approach. A total of 19 individuals with Type 2 diabetes participated in eight weeks of 30 min online physical exercise intervention followed by 30 min online group meetings in smaller groups once a week. Outcomes included pre-defined research progression criteria, secondary measurements of health parameters, and participant feedback. Most research progression criteria reached a level of acceptance, with the exception of participant recruitment, burden of objectively measured physical activity, and adverse events, where changes are needed before continuing to an RCT. Combining online physical exercise with online group meetings supported by an activity watch is feasible and acceptable in individuals with Type 2 diabetes with a higher educational level compared to the general population with Type 2 diabetes.
Changes in Mental Health, Emotional Distress, and Substance Use Affecting Women Experiencing Violence and Their Service Providers during COVID-19 in a U.S. Southern State
Authors: Schweinhart April , Aramburú Camila , Bauer Rachel , Simons-Rudolph Ashley , Atwood Katharine , Luseno Winnie Kavulani
Published: February 2023

Research conducted during the COVID-19 pandemic has revealed many unintended consequences of mandated safety precautions, including increased perpetration of intimate partner violence (IPV), increases in substance use, and worsening mental health conditions. We conducted a repeated, cross-sectional survey of survivors of IPV, a longitudinal survey of service providers working in an IPV shelter, and interviews with both. We conducted surveys at the beginning of the pandemic and nearly half a year later to assess mental health and, for clients, substance use. Results showed that two small samples of survivors living in the shelter in 2020 and 2021 experienced both mental health decline and increased use of substances. Qualitative data from in-depth interviews suggest that COVID-19-related restrictions mirrored survivors’ experiences of power and control in violent relationships. Further, IPV service providers—essential workers during COVID-19—experienced stress associated with reports of burnout and mental fatigue. This study suggests that community-based organizations can help mitigate the impacts of COVID-19 on survivors of IPV but should avoid adding additional work for staff as service providers experienced mental and emotional stress.
Does Internet Use Promote Subjective Well-Being? Evidence from the Different Age Groups Based on CGSS 2017 Data
Authors: Yan Yurong , Deng Yuying , Igartua Juan-José , Song Xiagang
Published: February 2023

Mobile Internet technology has developed so rapidly that the Internet has become indispensable in everyday life. There is a continuous debate about the relationship between internet use and subjective well-being. In contrast to observing whether one has Internet access, this paper focuses on three dimensions of Internet usage: frequency of use, online relationship size, and Internet proficiency. Based on the Chinese nationwide data collected in 2017, the results of the ordinary least squares regression model demonstrate that Internet use has a significant positive association with subjective well-being. In addition, this study also discovers that the effect of Internet use on the subjective well-being of individuals of different ages is heterogeneous; middle-aged individuals benefit from more frequent Internet use and larger-scale networks; the young and older adults benefit from organizing communication in groups. The results of this study can provide targeted suggestions for improving the subjective well-being of different age groups in Internet use.
Quality of Life and Psychosocial Well-Being among Intersex-Identifying Individuals in Puerto Rico: An Exploratory Study
Authors: Esteban Caleb , Ortiz-Rodz Derek Israel , Muñiz-Pérez Yesibelle I. , Ramírez-Vega Luis , Jiménez-Ricaurte Coral , Mattei-Torres Edna , Finkel-Aguilar Victoria
Published: February 2023

Purpose: Intersex is an umbrella term used to describe the diversity or differences in the characteristics of physical sexual development. Approximately 1.7% of the population are born intersex, and 1 in every 2000 babies at birth presents genital variation. Unfortunately, there is a lack of research on the health of intersex-identifying persons in Latin America. This study aimed to document experiences of discrimination and violence among self-identifying intersex individuals in Puerto Rico and to determine if there is a significant difference in the quality of life, psychological well-being, and social well-being between intersex-identifying and endosex individuals. Methods: This was a quantitative method pilot study with a cross-sectional approach and exploratory comparative group design. An online survey was used, where a total of 12 self-identifying intersex adult participants were recruited, and 126 endosex adult participants served as a comparative group. Results: The findings show that 83% of the participants reported experiences of discrimination and different types of violence due to their intersexuality. There was a significant difference between the intersex-identifying and endosex groups in psychological well-being, including in three of its dimensions (positives relations, autonomy, and environmental mastery). However, there were no significant differences between the groups in quality of life or social well-being. Conclusion: The findings of this study provide a preliminary understanding of the health disparities of intersex-identifying individuals in Puerto Rico and suggest the need for more profound research, especially the inclusion of other Caribbean and Hispanic countries. The findings also preliminarily imply the need for local and global interventions to reduce physical and mental health disparities and to improve health, quality of life, and well-being among intersex-identifying individuals.
Perception and Practice of Workplace Violence Prevention and Its Associated Factors among Employers at Healthcare Facilities in Melaka, Malaysia
Authors: Mohamad Yazid Mohd Nizam , Nik Husain Nik Rosmawati , Daud Aziah , Osman Yelmizaitun , Mustapa Normazura , Abdul Hadi Azlihanis
Published: February 2023

Workplace violence (WPV) is a major public health concern, especially among healthcare workers. There is a negative perception and poor practice of healthcare employers towards WPV prevention. This study aims to determine the perception and practice towards WPV prevention and its associated factors among healthcare employers in Melaka, Malaysia. A cross-sectional study was conducted by recruiting 162 healthcare employers, using a validated questionnaire and utilised linear regression analysis. The participants had a mean percentage of 67.2% for perception and 80% for practice towards WPV prevention. The perception towards WPV prevention is associated with the following characteristics: female (adjusted ß = −3.95; 95% CI: −7.81, −0.09; p = 0.045), Indian ethnicity (adjusted ß = 16.04; 95% CI: 2.34, 29.74; p = 0.022), other ethnicities (adjusted ß = 25.71; 95% CI: 8.94, 42.47; p = 0.003), degree holder (adjusted ß = 4.35; 95% CI: 0.15, 8.54; p = 0.042), masters holder (adjusted ß = 7.63; 95% CI: 1.11, 14.14; p = 0.022), and enough funds (adjusted ß = −5.46; 95% CI: −9.25, −1.67; p = 0.005). Meanwhile, the practice towards WPV prevention is significantly associated with Chinese ethnicity (adjusted ß = −9.25; 95% CI: −18.36, −0.14; p = 0.047), Indian ethnicity (adjusted ß = −14.97; 95% CI: −29.48, −0.46; p = 0.043), other ethnicities (adjusted ß = 23.55; 95% CI: 5.59, 41.51; p = 0.011), degree holder (adjusted ß = −4.41; 95% CI: −8.67, −0.14; p = 0.043), and availability of standard operating procedure for reporting WPV (adjusted ß = 6.07; 95% CI: 1.58, 10.57; p = 0.008). The high perception and practice towards WPV prevention and its associated factors among healthcare employers provide evidence-based input to improve the existing measures for WPV prevention.
Using Rapid-Cycle Change to Improve COVID-19 Vaccination Strategy in Primary Care
Authors: Hunt Lindsay S. , Sullivan Erin E. , Susa Jordan , Chaufournier Roger , Joseph Claudine , Phillips Russell S. , Meisinger Kirsten
Published: February 2023

During the COVID-19 pandemic, misinformation and distrust exacerbated disparities in vaccination rates by race and ethnicity throughout the United States. Primary care, public health systems, and community health centers have shifted their vaccination outreach strategies toward these disparate, unvaccinated populations. To support primary care, we developed the SAVE Sprint model for implementing rapid-cycle change to improve vaccination rates by overcoming community outreach barriers and workforce limitations. Participants were recruited for the 10-week SAVE Sprint program through partnerships with the National Association of Community Health Centers (NACHC) and the Resilient American Communities (RAC) Initiative. The majority of the participants were from community health centers. Data were evaluated during the program through progress reports and surveys, and interviews conducted three months post-intervention were recorded, coded, and analyzed. The SAVE Sprint model of rapid-cycle change exceeded participants’ expectations and led to improvements in patient education and vaccination among their vulnerable populations. Participants reported building new skills and identifying strategies for targeting specific populations during a public health emergency. However, participants reported that planning for rapid-pace change and trust-building with community partners prior to a health care crisis is preferable and would make navigating an emergency easier.
Prevalence and Factors Associated with Anxiety and Depression in Peruvian Medical Students
Authors: Piscoya-Tenorio Jorge L. , Heredia-Rioja Walter V. , Morocho-Alburqueque Noelia , Zeña-Ñañez Sandra , Hernández-Yépez Palmer J. , Díaz-Vélez Cristian , Failoc-Rojas Virgilo E. , Valladares-Garrido Mario J.
Published: February 2023

During medical training, students are exposed to stressors that deteriorate mental health. This study determined depression and anxiety prevalence and their associated factors in students from four medical schools in northern Peru. A cross-sectional study was conducted among medical students from Lambayeque, Peru. The Goldberg Anxiety and Zung Depression tests were applied. The dependent variables were depression and anxiety, and their association with covariates (age, sex, type of university, socioeconomic level, experience, family problem, and physical activity) was evaluated. Prevalence ratios were calculated using generalized linear models. Of 482 students, the prevalence of anxiety was 61.8% and depression was 22.0%. A severe level of anxiety was observed in 6.2% in the group between 16 and 20 years old. It was observed that private university students had higher frequencies of having depression (PR = 2.01) and anxiety (PR = 1.35); males had a lower risk of anxiety (PR = 0.82), but higher risk of depression compared to females (PR = 1.45). Performing physical activity decreased the prevalence of depression (PR = 0.53); however, it increased the frequency of anxiety (PR = 1.26). Having family problems increased the prevalence of anxiety (PR = 1.26). Medical students from private universities experienced higher rates of depression and anxiety. Depression and anxiety were associated with gender and physical activity. These findings highlight the importance of mental health promotion due to its link with quality of life and academic performance.
Experiences of Preconception Counseling among Pregnant Women with Preexisting Diabetes: Opportunities to Improve Patient-Centered Care
Authors: Marshall Cassondra J. , Parham Lindsay , Hubbard Erin , Irani Roxanna A.
Published: February 2023

Available research suggests that patients with diabetes do not regularly receive preconception counseling, but information on patients’ experiences of counseling is scant. We conducted a qualitative study involving semi-structured interviews with 22 patients between October 2020 and February 2021. Pregnant patients with preexisting diabetes were recruited from a specialty diabetes and pregnancy clinic at a large academic medical center in Northern California. Interviews were transcribed, coded, and analyzed using an inductive and deductive content analysis approach. A total of 27% reported they did not have any pregnancy-related discussions with a health care provider before pregnancy. Of those that did, many sought out counseling; this was often connected to how “planned” the pregnancy was. Few participants, nearly all with type 1 diabetes, reported having a formal preconception care visit. Participants described receiving information mostly about the risks associated with diabetes and pregnancy. While participants who sought out counseling generally reported their providers were supportive of their desire for pregnancy, there were a few exceptions, notably all among patients with type 2 diabetes. The varied experiences of participants indicate gaps in the delivery of pre-pregnancy counseling to patients with diabetes and suggest counseling may vary based on diabetes type. There are opportunities to improve the patient-centeredness of counseling.
Crisis, What Crisis? The Effect of Economic Crises on Spending on Online and Offline Gambling in Spain: Implications for Preventing Gambling Disorder
Authors: Chóliz Mariano
Published: February 2023

(1) Background: In the period between 2008 and 2020, the world experienced two global economic crises that affected people’s way of life and well-being: the financial crisis of 2008 and that precipitated by the COVID-19 pandemic. Despite the crises’ radically different causes, their consequences for economic activity have been equally dramatic; (2) Methods: This article analyzes the consequences of both crises on gambling spending in Spain and compares traditional (offline) games with more recent online offerings. The data were collected from databases maintained by the Spanish government and gambling companies; (3) Results: The paper offers two main conclusions. The first is that, while traditional (offline) gambling has been significantly affected by economic crises, online gambling has exhibited consistent growth since its legalization. The second is that the measures implemented to resolve the two economic crises differed significantly and thus had different impacts on spending on the various types of gambling; (4) Conclusions: The key conclusion is that purchasing power (measured in terms of GDP) can only explain spending on less addictive gambling games, such as lotteries. However, the availability and accessibility of games are both directly related to spending on games of all types.
Contribution of Accessibility to Urban Resilience and Evacuation Planning Using Spatial Analysis
Authors: Tsai Meng-Ting , Chang Hung-Wen
Published: February 2023

Cities evolve and change with economic development and population growth, and urban planning laws in Taiwan have regulations that should be comprehensively reviewed every six years. Most current government policies aim to add new disaster prevention shelters or rescue stations. An economical way to improve the disaster prevention capabilities of urban planning is through examining or reviewing spatial structures and disaster prevention plans from the perspective of citizens or residents. The UN Office of Disaster Risk Reduction (UNDRR) launched the Making Cities Resilient Campaign policy to enhance disaster-resistant and sustainable urban environments through integrated disaster mitigation, reduction, response, and evacuation plans. This study used space syntax to ascertain evacuation route features using geometric distance analysis. There was 31.61% efficiency in relation to accessible roads on a comprehensive map. We could clearly see that since the areas in the first quadrant were relatively close to accessible roads, and there was an area that was not connected to the existing evacuation channels. The increased number of channels was more accessible and extensive. Such suggestions are helpful for government departments to prepare for disaster management. The spatial characteristics of the physical environment are explained by the accessibility and efficiency of axial maps and visibility analyzed by space syntax. Our findings reveal that space syntax is an important application when examining evacuation maps.
Distributed Acoustic Sensing Based on Microtremor Survey Method for Near-Surface Active Faults Exploration: A Case Study in Datong Basin, China
Authors: Song Ao , Ren Junjie , Liu Aichun , Zhang Guangwei , Lei Xiaoqiong , Zhang Hao
Published: February 2023

Active fault detection has an important significance for seismic disaster prevention and mitigation in urban areas. The high-density station arrays have the potential to provide a microtremor survey solution for shallow seismic investigations. However, the resolution limitation of the nodal seismometer and small-scale lateral velocity being inhomogeneous hinder their application in near-surface active fault exploration. Distributed acoustic sensing (DAS) has been developed rapidly in the past few years; it takes an optical fiber as the sensing medium and signal transmission medium, which can continuously detect vibration over long distances with high spatial resolution and low cost. This paper tried to address the issue of near-surface active fault exploration by using DAS. We selected a normal fault in the southern Datong basin, a graben basin in the Shanxi rift system in north China, to carry out the research. Microtremor surveys across the possible range of the active fault were conducted using DAS and nodal seismometers, so as to obtain a shallow shear wave velocity model. Meanwhile, we applied a Brillouin optical time domain reflectometer (BOTDR) and distributed temperature sensing (DTS) to monitor the real-time fluctuation of ground temperature and strain. Our results show that the resolution of the deep structures of the fault via the microtremor survey based on DAS is lower than that via the seismic reflection; whereas, their fault location is consistent, and the near-surface structure of the fault can be traced in the DAS results. In addition, both the BOTDR and DTS results indicate an apparent consistent change in ground temperature and strain across the fault determined by the DAS result, and the combination of surface monitoring and underground exploration will help to accurately avoid active faults and seismic potential assessment in urban areas.
Is There Any Difference in the Quality of CPR Depending on the Physical Fitness of Firefighters?
Authors: Lee HyeonJi , Ahn JiWon , Choi Youngsoon
Published: February 2023

(1) Background: The purposes of this study were to develop a physical fitness evaluation program for new firefighters, to investigate whether there is a quality difference in performing CPR for cardiac arrest patients according to physical strength, and to provide basic data to improve CPR quality. (2) Methods: The subjects of this study were fire trainees who were appointed as firefighters for the first time in G province from 3 March 2021 to 25 June 2021. The age of the subjects was 25–29 years old, and their experience of working as a firefighter was less than three months. According to the purposes of the study, the researcher composed the Physical Fitness Evaluation Program, including the physical fitness evaluation method and steps, and requested a content expert group to modify and supplement the ‘physical fitness assessment program’. The subjects were divided into four groups according to their levels of physical strength, and CPR was performed for 50 min in groups of two. A high-end Resuscitation Anne Simulator (Laeadal, Norway) mannequin was used to evaluate the quality of CPR. (3) Results: When comparing the difference in CPR quality, there were statistically significant differences in the number of chest compressions and compression depth, but all groups met the CPR guidelines. In the case of this study, it is thought that high-quality CPR could be performed because the subjects’ average age was low and they continued to exercise to improve their physical strength for their role. (4) Conclusions: It was concluded that the fitness level of new firefighters confirmed by this study was sufficient for general high-quality CPR. In addition, for high-quality CPR, continuous management is required by developing a continuous CPR education and physical training program for all firefighters.
Recognizing and Responding to Anti-Science in Environmental and Public Health Research and Practice
Authors: Øvretveit John
Published: February 2023

This perspectives article considers the challenges posed by anti-science and how we can use research to respond more effectively. In public health, the challenges were more visible and the impact more serious during the COVID-19 pandemic. In part, this was due to a more organized anti-science and effective use of narrative methods. Regarding climate change, the role of anti-science represents a critical issue, but perhaps more recognized in environmental research and practice. The article draws on a narrative review to show some of the research into the nature of anti-science and the challenges it poses. It proposes that, as researchers, practitioners, and educationalists, we can be more effective if we make more use of recent research in the sciences of communications, behavior, and implementation, and shows some of the resources we can use to help our work be more relevant in the new era in which we are living.
Patient-Reported Outcomes and Experiences Assessment in Women with Breast Cancer: Portuguese Case Study
Authors: Coelho Anabela , Kendir Candan , Barrenho Eliana , Klazinga Niek , Paiva Cláudia , Abreu de Sousa Joaquim , Gonçalves-Monteiro Salomé , Redondo Patrícia , Bastos Ana , Nogueira Armanda , Guedes Fábio Botelho , Costa Andreia Silva , Gaspar Tânia
Published: February 2023

In 2020, female breast cancer was the most commonly diagnosed cancer worldwide, representing the type of cancer with the highest incidence among women and the second most common cause of cancer death among women in all OECD countries. The conventional measures addressing the burden of breast cancer by measuring mortality, incidence, and survival do not entirely reflect the quality of life and patients experience when receiving breast cancer care. The main objective of this study is to capture patient-reported outcomes and experiences in women with breast cancer in Portugal using methods developed for international benchmarking purposes, such as the OECD Patient-reported Indicators Surveys. The study included 378 women with breast cancer, with the age distribution being 19.8% aged 15 to 49 years and 80.2% aged 50 years and over. The data collection procedure and analysis followed the “OECD Breast Cancer Patient Reported Outcomes Working Group” protocol, allowing subsequent comparability with data from other OECD member countries. Most women were satisfied with the treatment outcome regarding the shape of their lumpectomy breast when wearing a bra (96.1%) and with the equal size of both breasts (78.3%). Findings on the WHO QOL-BREF showed that women manifest a lower score in well-being when compared with the general population or populations living with chronic diseases. This study shows the feasibility of implementing and using patient-reported metrics (PROM and PREM) in breast cancer services in Portugal. Measuring PROMs and PREMs from Portuguese women receiving breast cancer care provides insightful evidence into the quality and value of cancer care.